baber/WOPTO huggingface dataset:
Patent CR-20160496-A (CR)
Title: Inhibidores espirocíclicos sustituidos de la autotaxina
Inventor: XIE ZHIFENG
IPC: C07D221/20
Filed: 2015-04-03
Abstract: La presente invención se refiere a compuestos según la fórmula I: y sales farmacéuticamente aceptables, síntesis, intermedios, formulaciones, y métodos de tratamiento con las mismas enfermedades, incluyendo cáncer, homing de linfocitos, inflamación crónica, dolor neuropático, enfermedades fibróticas, trombosis, y prurito colestásico, mediados al menos en parte por ATX.
Patent CR-20190204-A (CR)
Inventor: SCOTT JAMES STEWART
IPC: C07D471/04
Filed: 2017-10-13
Abstract: La memoria descriptiva se refiere a compuestos de Fórmula (I):(I) y a sales farmacéuticamente aceptables de los mismos, a procesos e intermedios usados para su preparación, a composiciones farmacéuticas que los contienen y a su uso en el tratamiento de trastornos proliferativos celulares.The specification relates to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, to processes and intermediates used for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of cell proliferative disorders.
Patent EC-SP003858-A (EC)
Title: Metodo de fabricacion de barras de reposteria
Inventor: LEFEBVRE RENE
IPC: A23G9/24
Filed: 2000-12-28
Abstract: La presente invención se relaciona a un método para la fabricación de barras individuales de repostería que comprende un centro en tres dimensiones y al menos una capa de material de repostería a base de azúcar cocida que reviste en parte al menos al centro. El método comprende la calibración de al menos una banda continua (7) de material de repostería sobre un rodillo de enfriamiento(4); el desprendimiento de la banda y el depósito de la banda (7) sobre una base (3) por contacto de estar sensiblemente según un plano (p) adyacente a la superficie/línea de contacto más elevada de la base de repostería para revestir; la banda es llevada al momento del depósito a un estado viscoplático tal que la banda (7) es apta a deformarse bajo su propio peso para revestir en parte al menos las caras de la base por debajo de la superficie/linea de contacto.
Patent EC-SP055717-A (EC)
Title: Conjugados de polimero con antigenicidad disminuida. metodos de preparacion y usos de los mismos
Inventor: MARTINEZ ALEXA
IPC: A61K47/48
Filed: 2005-04-05
Abstract: Se proporcionan métodos para la preparación de conjugados de una variedad de componentes bioactivos, especialmente proteínas, con polímeros solubles en agua (por ejemplo, polietilenglicol y derivados del mismo), cuyos conjugados tienen antigenicidad e inmunogenicidad reducidas comparadas con conjugados similares preparados utilizando polietilenglicol que contiene un grupo metoxilo u otro alcoxilo. La invención también proporciona conjugados preparados por dichos métodos, composiciones que comprenden dichos conjugados, kits que contienen dichos conjugados o composiciones y métodos de uso de los conjugados y composiciones en protocolos terapéuticos y de diagnóstico.
Patent EC-SP056122-A (EC)
Title: "espuma zebra"
Inventor: REYES CAMPANA MARTES
IPC: A99Z99/00
Filed: 2005-10-25
Abstract: La pigmentación tipo ZEBRA en continuo en un proceso de producción de espuma, en forma de líneas verticales con la posibilidad de ser en diferentes colores, combinaciones, anchos y numero de líneas así como diferente forma de líneas, como recta irregular ó regular, ondulada ó en zigzag, es un proceso que solo es posible llevarlo a cabo por medio de un dispositivo mecánico diseñado por el acoplamiento de varios elementos formando una UNIDAD, encargada de llevar a cabo los pasos : -SEPARACION-MEZCLA-PIG MENTA CION-REPARTICION Y -VACIADOLa finalidad de la invención, es la de producir por medio de un dispositivo llamado UNIDAD ZEBRA, un producto que:a) Técnicamente sea infalsificable.b) Crear una espuma con un sello característico de quien lo produce.c) Es un producto novedoso y presenta una armonía estética.d) No ofrece ninguna desventaja técnica ni física.e) No afecta las propiedades originales del producto.f) Crea un producto con una característica permanente de identificación.g) Característica imborrable, una vez aplicada al producto.DESCRIPCION DE LOS DIBUJOSLos detalles característicos de este novedoso dispositivo se muestran claramente en la siguiente descripción y en los dibujos que se acompañan, así como una ilustración de aquel, y siguiendo los mismos signos de referencia para indicar las partes de las figuras mostradas.La figura 1.- es la perspectiva convencional del elemento múltiple primario.La figura 2. - es la perspectiva convencional del elemento mezclador estático y su acoplamiento.La figura 3.- es la perspectiva del múltiple secundario, válvula neumática reguladora de presión y conductor flexible con su acoplamiento.La figura 4.- es la presentación de la línea general completa desde la salida del múltiple primario hasta la conexión con el recipiente contenedor de los materiales, cuando es empleado un múltiple secundario.La figura 5.- es la presentación de la línea general, completa desde la salida del múltiple primario hasta la conexi6n con el recipiente de los materiales, cuando se usa la línea directa sin el empleo de un múltiple secundario.La figura 6.- es la presentación del recipiente contenedor de los materiales y las partes involucradas en su uso para recibir los caudales individualmente.
Patent EC-SP056242-A (EC)
Title: Mezclas fungicidas
Inventor: STIERL REINHARD
IPC: A01N43/90
Filed: 2005-12-21
Abstract: La presente invención se refiere a mezclas fungicidas, que contienen 1)	el derivado de triazolopirimidina de la fórmula I, y2)	una pirimidinanilida de la fórmula II, en la que R significa metilo, ciclopropilo ó 1-propinilo, en una cantidad sinergética activa, procedimientos para combatir hongos nocivos de la clase de los oomicetos con mezclas del compuesto I con uno de los compuestos II y el uso del compuesto I y uno de los compuestos II para la obtención de tales mezclas, así como productos que contienen estas mezclas.
Patent EC-SP066269-A (EC)
Title: Derivados de diaril y arilheteroaril urea como moduladores del receptor 5-ht2a de serotonina útiles para la profilaxis y tratamiento de desórdenes relacionados con el mismo
Inventor: TEEGARDEN BRADLEY
IPC: C07D405/12
Filed: 2006-01-05
Abstract: La presente invención se refiere a ciertos derivados de pirazol de Fórmula (I) y a las composiciones farmacéuticas de los mismo, que modulan la actividad del receptor de serotonina 5TH2A Los compuestos y las composiciones farmacéuticas de los mismos están dirigidas a métodos que son útiles para la profilaxis o tratamiento de la agregación de plaquetas, para la enfermedad de las arterias coronarias, infarto de miocardio, accidentes isquémicos transitorios, angina, apoplejía, fibrilación auricular, reducción del riesgo de formación de coágulos de sangre, asma o síntomas del mismo, agitación o un síntoma, desórdenes de conductismo, psicosis inducidas por fármacos, psicosis excitativa, síndrome de Gilles de la Tourette', desorden maníaco, psicosis orgánica o de NOS, desorden psicótico, psicosis, esquizofrenia aguda, esquizofrenia crónica, esquizofrenia de NOS y desórdenes relacionados, desórdenes del sueño, desórdenes relacionados con diabetes, y similares.La presente invención se refiere también al método de profilaxis o tratamiento de desórdenes intermediados por el receptor de serotonina 5HT2A en combinación con el antagonista del receptor D2 de dopamina tal como haloperidol, administrado por separado o en forma conjunta.
Patent EC-SP088223-A (EC)
Title: Método para el tratamiento de los frutos del café
Inventor: FRANZIN MAURICIO DA SILVA
IPC: A23F5/02
Filed: 2008-02-25
Abstract: La presente invención se refiere a un método para el tratamiento de los frutos del café, ya sea con piel y pulpa o en condición pulposa, al promover la desinfección de los frutos del café, con el objeto de evitar la fermentación de los granos, mediante microorganismos y para neutralizar algunas composiciones químicas metabólicas que son liberadas durante la fermentación inicial, para mantener inalterado o mejorar el sabor y aroma, para controlar la acidez del café a niveles deseables, y para garantizar la calidad del producto final, ya que estos microorganismos pueden ser patogénicos o endofíticos.
Patent EC-SP088356-A (EC)
Title: Pigmentos luminiscentes encapsulados
Inventor: DE CORTE DAVID
IPC: C09B67/08
Filed: 2008-04-09
Abstract: La presente invención se refiere a pigmentos luminiscentes encapsulados, que se encapsulan en una cubierta polimérica. Otros aspectos de la invención son composiciones de polímeros que contienen estos pigmentos luminiscentes encapsulados y su uso en dispositivos electrónicos y películas agrícolas.
Patent EC-SP099484-A (EC)
Title: Indazoles sustituidos con amida como inhibidores de
Inventor: JONES PHILIP STEPHEN
IPC: A61K31/4439
Filed: 2009-07-03
Abstract: La presente invención se refiere a los compuestos de Fórmula (I): y sales farmacéuticamente aceptables, estereoisómeros o tautómeros de los mismos que son inhibidores de la enzima poli(ADP-ribosa) polimerasa (PARP) y por tanto útil en el tratamiento del cáncer, enfermedades inflamatorias, lesiones por reperfusión, afecciones isquémicas, apoplejía, insuficiencia renal, enfermedades cardiovasculares, enfermedades vasculares distintas de las cardiovasculares, diabetes, enfermedades neurodegenerativas, infección retroviral, daño retiniano o senescencia de la piel y daño en la piel inducido por radiación UV, y como quimio- y/o radiosensibilizadores para tratamiento de cáncer.
Patent EC-SP982534-A (EC)
Title: Nuevo metodo de tratamiento
Inventor: SMITH STEPHEN ALISTAIR
IPC: C07D209/90
Filed: 1998-06-16
Abstract: La presente invención se refiere a un método para el tratamiento de diabetes mellitus y procesos asociados a la diabetes mellitus en un mamífero, cuyo método comprende administra una cantidad eficaz, no tóxica y farmacéuticamente eficaz de un sesibilizador a la insulina y un secretagogo de insulina a un mamifero con necesidad de ello.
Patent FI-20002793-A (FI)
Inventor: GREENE MORTON
IPC: G01S/
Filed: 2000-12-20
Abstract: A radio frequency automatic identification system detects targets which include solid resonators resonating at several frequencies, attributing information to the frequencies at which the target resonates. Preferred resonators are quartz crystals, which according to the invention, may be made by a process of heating quartz to soften it and cutting crystals to approximate size and resonant frequency. Resonators produced by such a process may be measured to determine their actual resonant frequency, and preferably the crystals may be sorted into predetermined frequency windows in accordance with their measured resonant frequency. A set of resonators having frequencies corresponding to predetermined data can be selected from the sorted groups of resonators and incorporated into a target. A preferred target is an ink-like material having a plurality of resonators disposed in a matrix which is radio frequency transparent at the frequency of interest. Targets maybe detected by repetitively sweeping the frequency of the interrogating signal through a range which includes the information-bearing range of the system. <IMAGE>
Patent FI-20002891-A (FI)
Inventor: MYLLYMAEKI PETRI JUKKA
IPC: H04B17/00
Filed: 2000-12-29
Abstract: A method for estimating a receiver's location in a wireless communication environment having several channels. Each channel has at least one signal parameter that varies with location differently from the other channels. A set of calibration data is determined for each calibration point, each set including the location and at least one measured signal parameter for each of several channels. The calibration data serve as a basis for a statistical model of the signal parameters versus a receiver's location. A set of observed signal parameters is determined, the set including at least one signal parameter for each of several channels at the receiver's location. A location estimate approximating the location of the receiver is determined on the basis of the statistical model and the set of observed signal parameters.
Patent FI-20020024-A (FI)
Inventor: WANG LINGHSIAO
IPC: H04L12/54
Filed: 2002-01-08
Abstract: A system and method for implementing a control channel in a packet switched communications network. In a computer network, such as a local area network (LAN) it is known to utilize the Ethernet for distributing communications between stations. The Ethernet employs a standard frame format that includes header frames and, in particular a preamble frame which may be used to provide synchronization information between switching devices or nodes. The preamble frame is not required in a Gigabit Ethernet implementation and the present invention employs a portion of the preamble frame to implement a control channel between switching devices.
Patent FR-1198872-A (FR)
Inventor: GERTSCH ERNST
IPC: A63C9/085
Filed: 1958-02-14
Granted: 1959-12-10
Abstract: 827,119. Skis. GERTSCH, E. Feb. 11, 1958 [Feb. 14, 1957], No. 4479/58. Class 132(1) A ski-stopping device comprises a brake lever pivoted to the ski which, on release of the ski-fastening moves from an ineffective to an effective position protruding downwardly beyond the sliding surface of the ski to brake the detached ski. Ski-boot 2 has bolts 20 at its front and rear by which it is held in a safety binding comprising a front part 3 and a rear bolt 22 both secured to the ski 1 . Bolt 22 is movable manually against the tension of a spring 21 by a lever 23. A lever 6 of stiff sheet material is pivoted on a pin 5 mounted in members screwed to the sides of the ski and is biased to its vertical position, chain dotted lines Fig. 1, by a torsion spring. The rear arm 6a of the lever 6 carries a transverse terminal portion 6b which during skiing is held against the ski by the toe of the ski-boot thus holding lever 6 in its inoperative position. When the boot is removed suddenly, e.g. when the skier falls, the lever is released, end 6c engages the snow and the ski is prevented from sliding away. The lever may be locked in its inoperative position during transport by the end of a part slidable by means of flap 9a in grooves 10a in a member 10 secured to the ski and having a part 10b which covers pivot 5 and sping 7 (Fig. 2, not shown). As shown in Fig. 3, boot 2 is retained in a foot plate 13 at whose front end there is a pin 14 engaging a recess in a support 15 adjustably fastened to ski 1 by longitudinal slots. Hinged to a lateral part of support 15 there is a brake lever 17 spring biased to the position shown in chain dotted lines and having an extension 19 normally held under foot plate 13.
Patent GB-1046073-A (GB)
IPC: F16L11/08
Abstract: 1,046,073. Flexible pipes. INSTITUT FRANCAIS DU PETROLE, DES CABBURANTS ET LUBRIFIANTS. Jan. 21, 1964 [Jan. 22, 1963], No. 2652/64. Heading F2P. An armouring 4 consisting of two layers of wires are helically wound with inverse pitches over a core 1 of rubber or synthetic plastics material, each layer having an inclination of between 55 and 60 degrees in relation to the axis of the pipe and the armouring is covered by a sheath 5. At least two longitudinal tension-resisting wires 6, 7 substantially parallel to the axis of the pipe are secured to the sheath, and the core 1 is provided with two diametrically opposite, longitudinal notches 2, 3. In modifications,(a)the wires 6, 7 are disposed at an angle to the plane of the notches, and (b) there are three longitudinal wires angularly spaced apart by 120 degrees.
Patent GB-1051434-A (GB)
IPC: C08F279/02
Abstract: 1,051,434. Impact polymers. FOSTER GRANT CO. Inc. March 5. 1964 [March 5. 1963], No. 9446/64. Heading C3G. Impact polymers are prepared by a method comprising the steps of (a) dissolving a minor proportion of a natural rubber or a synthetic rubber derived from a conjugated diene in a major proportion of a liquid alkenyl aromatic monomer, (b) partially polymerizing the solution obtained to a pre-polymer of desired solids content, (c) admixing a low molecular weight alkenyl aromatic hydrocarbon polymer (i.e. such a polymer having a viscosity average molecular weight not exceeding 40,000) with the prepolymer and (d) further polymerizing the mixture so produced to a desired degree of conversion. The polymerization effected in steps (b) and (d) may be an emulsion or preferably, a bulk or suspension process. Additional liquid alkenyl aromatic monomer may be added in step (c). Suitable rubbers include natural crepe rubber, butadiene-styrene copolymers, in which the butadiene units may be stereoregular, butadiene-acrylonitrile copolymers, and polybutadiene or polyisoprene which may be stereoregulated. Styrene is preferred as the aromatic monomer, and the aromatic hydrocarbon polymer may be derived from styrene, vinyl toluene, vinylxyiene, ethyl vinylbenzene, isopropylstyrene and ethylvinyltoluene. In examples, the polymerization steps are effected using lauroyl peroxide as catalyst and dodecyl mercaptan as a molecular weight modifier.
Patent GB-1052632-A (GB)
IPC: B62D29/04
Abstract: 1,052,632. Cushions. LANTOR Ltd. and IMPERIAL CHEMICAL INDUSTRIES Ltd. Nov. 14, 1962 [Nov. 22, 1961], No. 41755/61. Heading A4M. [Also in Divisions B5 and D1] A cushion, e.g. for vehicle upholstery, comprises a mouldable laminated sheet material and an underlayer of foamed polyurethane, polyvinyl chloride, polystyrene or rubber. The sheet material comprises a thermoplastic sheet, e.g. of polyvinyl chloride, or other vinyl polymers, polypropylene, acrylonitrile-butadiene-styrene copolymers, or mixtures of these with polyvinyl chloride, bonded to a layer of non-woven fabric of thermoplastic fibres themselves bonded with a thermoplastic or non-thermoplastic bonding agent, the fibres being of polyvinyl chloride, polyvinyl chloride-acrylonitrile copolymer, polypropylene, or an acrylic polymer, and the bonding agent comprising plasticized polyvinyl chloride, polyvinylidene chloride, or other vinyl polymers, or polyacrylonitrile. The sheet material (which may be embossed) and the bonded fibre fabric laminated thereto may be moulded, e.g. into hollow form with the fabric as the inner layer, and the moulded body may be filled with a foamable mix of polyurethane prepolymer to form the cushion after foaming, the fabric providing an improved bonding surface for the foam.
Patent GB-1053043-A (GB)
IPC: G03C1/76
Abstract: 1,053,043. Coated surfaces. GEVAERT PHOTO-PRODUCTEN N.V. Jan. 23, 1964 [Jan. 25, 1963], No. 2943/64. Headings B2E and B2K. [Also in Divisions C3 and G2] In examples, mixtures of aqueous gelatin and aqueous lattices formed by emulsion polymerization of butadiene with alkyl esters of acrylic or methacrylic acid are coated onto glass plates and stretched subbed polyethylene terephthalate film.
Patent GB-1053247-A (GB)
IPC: B23K35/26
Abstract: 1,053,247. Alloys. PHILCO CORPORATION. Sept.4, 1963 [Sept.4, 1962], No.34933/63. Heading C7A. [Also in Division H1] A silver wire is attached to a transistor (see Division H1) by means of a solder containing tin, zinc and/or cadmium, and either about 0À01-0À04% or about 1% by weight of gallium.
Patent GB-1053519-A (GB)
IPC: A47K10/48
Abstract: 1,053,519. Hand dryÚrs. WARMEX Ltd. Oct. 5, 1964; No. 40559/64. Heading A5R. [Also in Division A4] A hand dryer comprises a cabinet 1, 2 containing means 8, 9 for discharging warm air from the bottom of the cabinet for a predetermined time under the control of a timing device 10, a removable holder for a stack of interleaved towels and means operable by withdrawal of a towel to actuate the timing device. A front compartment 1 of the cabinet, which has a bottom opening for the discharge of hot air. contains a blower 8, a main heater 9a controlled by the timing device and a preheater 19 which is controlled as desired by a manual switch. The rear compartment 2 receives a removable holder containing interleaved paper towels, the towels being so stacked that a portion of the bottom towel T hangs through bottom openings in the holder and the rear compartment. The holder is supported by rollers 4, 5 so that the hanging portion of the bottom towel passes over an operating roller 7. As the bottom towel is withdrawn, it rotates the operating roller. A blade 13, carried by a rocker arm 14 which is supported by the operating roller, then interrupts a beam of light between a lamp 12 and a photo-electric cell 11 to set the timing device in operation and cause the discharge of hot air for a predetermined time. When the towel has been withdrawn, the rocker. arm and blade are returned by gravity to their initial positions.
Patent GB-1054659-A (GB)
IPC: E02D15/06
Abstract: 1,054,659. Pipe couplings. INSTITUT FRANCAIS DU PETROLE, DES CARBURANTS ET LUBRIFIANTS. Feb. 21, 1964 [Feb. 21, 1963; Sept. 27, 1963], No. 7429/64. Heading F2G. [Also in Division E1] In apparatus for forming subaqueous structures (Divisions E1-E2) a flexible pipe T is attached to a container by means of a socket K. As shown pin D holds the end E of the pipe in co-operation with the socket K. To release the pipe a collar U is dropped along the pipe, the collar being of sufficient mass to compress spring R 2  so that the extremity of lever arm S relaxes lever arm L and allows spring R 1  to disengage pin G. The seal between the end E and socket K is effected by joint J which may be annular or toroidal. Fig. 5A (not shown) illustrates pin D as a shear pin which is fractured when pipe T is hauled up.
Patent GB-1226440-A (GB)
IPC: B63B27/18
Filed: 1968-12-13
Abstract: 1,226,440. Transhipping at sea. GENERAL ELECTRIC CO. Ltd., 9 Dec., 1969 [13 Dec., 1968], No. 59449/68. Heading B8E. In a high-line apparatus for transhipping at sea, one or both ends of the cable are supported on pivoted arms 5, Fig. 2, provided with means 8 for receiving a trolley 1, the arrangement being such that when the arm is lowered to set down a load the effective high point of the cable is transferred from a point inwards of the end of the arm, i.e. the pivot 9, to a point further out along the arm at or in the vicinity of the trolley. Fig. 4 shows the disposition of the apparatus in the lowered position of the arm 5. Figs. 5 and 7 show an embodiment in which the trolley is pulled along a jack-stay 14 by a cable 23. In Fig. 8 an arm 35 is supported by a jackstay 36 which passes over a pulley 38 and is pulled down into the unloading position by a cable 47. When the apparatus is in position C the hauling cable 49 is paid out to lower the load to the ground.
Patent GB-1227375-A (GB)
IPC: C07D241/52
Filed: 1968-07-09
Abstract: 1,227,375. 2 - Methyl - 3 - cyano - quinoxaline di-N-oxides. FARBENFABRIKEN BAYER A.G. 9 July, 1968 [8 Aug., 1967], No. 32749/68. Addition to 1,187,991. Heading C2C. The invention comprises quinoxaline di-N- oxides of the formula wherein R represents hydrogen, halogen or an alkyl, alkoxy, carbalkoxy, carboxylic amide or sulphonamido group, in which the amide groups may be mono- or di-alkyl-substituted, and the preparation thereof by heating to 40-80‹ C., in a water-miscible organic solvent, 5-methyl-isoxazole, or an isomeric mixture of 4- and 5-methylisoxazoles, with at least an equimolar amount, based on 5-methylisoxazole, of an alkali metal hydroxide or alcoholate and reacting the resulting solution, if desired after cooling to 15-25‹ C., with an equimolar amount, based on 5-methyl-isoxazole, of a benzofuroxane of the formula in a water-miscible organic diluent in the presence of at least equimolar amounts, based on benzofuroxane, of ammonium chloride and ammonia at 20-80‹ C. Specified solvents and diluents include alcohols, cyclic ethers, dimethylformamide and acetamide and dimethylsulphoxide. Examples relate to the preparation of compounds in which R is hydrogen, chlorine, a methyl and a methoxy group.