baber/WOPTO huggingface dataset:
Patent WO-2020123769-A1 (WO)
Title: Génération et cryoconservation de cellules endothéliales cornéennes de grade clinique dérivées de cellules souches pluripotentes
Inventor: RIAZUDDIN S AMER
IPC: A61K35/30
Filed: 2019-12-12
Abstract: La présente invention concerne la génération et la cryoconservation de cellules endothéliales cornéennes (CEC) de grade clinique dérivées de cellules souches embryonnaires humaines (hESC) et de cellules souches pluripotentes induites (iPSC) par l'intermédiaire du lignage de cellules de crête neurale (NCC) au moyen de sang périphérique en tant que source donneuse et les hESC maximisent la disponibilité de ces cellules vitales pour traiter la maladie endothéliale cornéenne en tant qu'alternative aux cornées donneuses pour des greffes d'endothélium cornéen (CE) et d'autres applications.
Patent WO-2020142357-A1 (WO)
Title: Structure de tige d'un article chaussant comprenant un élément de manchon
Inventor: COOPER AARON AC
IPC: A43B23/02
Filed: 2019-12-27
Abstract: La présente invention concerne une structure de tige d'un article chaussant comprenant une tige, un élément de manchon et un montage Strobel. La tige comprend un élément de tige extérieur et un élément de tige intérieur. L'élément de manchon comprend une première extrémité couplée à l'élément de tige extérieur et une seconde extrémité couplée à l'élément de tige intérieur. L'élément de manchon est replié sur lui-même au niveau d'un pli pour définir une ouverture de cheville. Le montage Strobel est couplé à la tige et coopère avec la tige pour définir au moins partiellement un vide recevant le pied.
Patent WO-2020160115-A1 (WO)
Inventor: SCHULTE JAMES PATRICK II
IPC: C08G73/10
Filed: 2020-01-29
Abstract: La présente invention concerne un procédé de fabrication d'une composition de dianhydride de biphénol comprenant le chauffage d'une première solution contenant un tétraacide de biphénol de formule (I) dans laquelle Ra, Rb, p et q sont tels que définis dans la description ; au moins un des ions de sodium, des ions de calcium, des ions de zinc, des ions d'aluminium, des ions de fer, des ions de phosphate, des ions de sulfate, des ions de chlorure, des ions de nitrate et des ions de nitrite ; et un solvant non halogéné. La première solution est chauffée dans des conditions efficaces pour fournir une seconde solution comprenant le dianhydride de biphénol correspondant, le ou les ions de sodium, les ions de potassium, les ions de calcium, les ions de zinc, les ions d'aluminium, les ions de fer, les ions de phosphate, les ions de sulfate, les ions de chlorure, les ions de nitrate et les ions de nitrite, et le solvant non halogéné.
Patent WO-2020180793-A1 (WO)
Inventor: IANCHULEV TSONTCHO
IPC: A61K31/4178
Filed: 2020-03-02
Abstract: The present disclosure provides methods and devices for delivering pilocarpine to the eye. In certain aspects, the disclosure provides method for delivering a composition comprising pilocarpine to an eye of a subject in need thereof as a micro-dose stream of droplets. In certain embodiments, the method treats or alleviates one or more symptoms of presbyopia, in particular presbyopia in adults 40 years of age or older, in the subject in need thereof. In certain embodiments, the present disclosure utilizes relatively high concentrations of pilocarpine in the solution to be administered and as a single active agent.
Patent WO-2021061187-A1 (WO)
Inventor: HSU I-MING
IPC: H05B45/40
Filed: 2020-03-02
Abstract: An apparatus is for auxiliarily detecting a defect of a lighting device including LED sets, and includes voltage detector circuits connected respectively to the LED sets, a load circuit connected to the LED sets in parallel, a switch circuit connected between the load circuit and a ground, and a control circuit connected to the voltage detector circuits and the switch circuit. Each of the voltage detector circuits detects a voltage drop across a corresponding one of the LED sets. The control circuit controls the switch circuit to switch between a conducting state to make an electric connection between the load circuit and the ground, and a non-conducting state to break the electric connection according to the voltage drops.
Patent WO-2020190634-A1 (WO)
Title: Ensemble rétroviseur à refroidissement amélioré
Inventor: VEENMAN STEVEN J
IPC: B60R1/04
Filed: 2020-03-12
Abstract: L'invention concerne un ensemble rétroviseur comprenant un dispositif de rétroviseur ; un boîtier contenant le dispositif de rétroviseur ; une cavité délimitée par le boîtier et le dispositif de rétroviseur ; une première carte de circuit imprimé comportant un processeur et disposée à l'intérieur de la cavité ; une seconde carte de circuit imprimé en communication avec la première carte de circuit imprimé et disposée à l'intérieur de la cavité ; au moins une nervure comportant un bord extérieur et s'étendant depuis le boîtier dans la cavité ; et un canal dont les parois latérales sont délimitées par une partie du boîtier, ladite nervure, et une partie de la seconde carte de circuit imprimé. Un dispositif de déplacement d'air peut aspirer de l'air à travers le canal. Un joint peut être utilisé pour rendre les parois latérales du canal généralement étanches à l'air.
Patent WO-2020186085-A1 (WO)
Title: Oxygen monitoring and control system
Inventor: COMMERFORD BERNARD LAWRENCE
IPC: A61M16/20
Filed: 2020-03-12
Abstract: An Automatic Supplemental Oxygen Control unit, a portable device that automatically monitors and adjusts the flow of supplemental oxygen to the subject in response to the oximetry and other readings derived from sensors attached to the subject and the oxygen source and provides programmed responses to physical inputs from such sensors to provide a closed loop oxygen delivery system.
Patent WO-2020191233-A1 (WO)
Title: Methods and compositions for editing nucleotide sequences
Inventor: LIU DAVID R
IPC: C12N9/12
Filed: 2020-03-19
Abstract: The present disclosure provides compositions and methods for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The nucleotide change can include a single- nucleotide change (e.g., any transition or any transversion), an insertion of one or more nucleotides, or a deletion of one or more nucleotides. More in particular, the disclosure provides fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named an PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap, which is homologous to a strand of the targeted endogenous DNA sequence to be edited, but which contains the desired one or more nucleotide changes and which, following synthesis by the polymerase (e.g., reverse transcriptase), becomes incoporated into the target DNA molecule. Also disclosed herein are various methods that leverage prime editing, including treating trinucleotide repeat contraction diseases, installing targeted peptide tags, treating prion disease through the installation of protection mutations, manipulating RNA-encoding genes for the installation of RNA tags for controlling the function and expression of RNA, using prime editing to construct sophisticated gene libraries, using prime editing to insert immunoepitopes into proteins, use of prime editing to insert inducible dimerization domains into protein targets, and delivery methods, among others.
Patent WO-2020205642-A1 (WO)
Title: Method and system for data futures platform
Inventor: BLAIKIE III ALFRED BLAIR
IPC: G06Q40/00
Filed: 2020-03-27
Abstract: A system, method, and platform for performing transactions for data. The data is grouped. The data is associated with a platform. Transaction information for the data is received. One or more transactions are performed based on the transaction information. The verification of the transaction is provided.
Patent WO-2021201860-A1 (WO)
Inventor: LIBSTER DIMA
IPC: C08G77/04
Filed: 2020-04-01
Abstract: There is described an intermediate transfer member for digital offset printing, comprising: a cured silicone release layer formed by curing a curable silicone release formulation comprising: a polyalkylsiloxane containing at least two vinyl groups having a weight average molecular weight of 60,000 g/mol or less; a polyalkylsiloxane containing two vinyl groups having a weight average molecular weight of at least 65,000 g/mol; a polyalkylsiloxane cross-linker containing at least two Si-H bonds; and a catalyst or a photoinitiator. There is also described a method of producing an intermediate transfer member, and a curable silicone release formulation for an intermediate transfer member.
Patent WO-2020210410-A1 (WO)
Title: Defect candidate generation for inspection
Inventor: PLIHAL MARTIN
IPC: G01N21/95
Filed: 2020-04-09
Abstract: Systems and methods for detecting defect candidates on a specimen are provided. One method includes, after scanning of at least a majority of a specimen is completed, applying one or more segmentation methods to at least a substantial portion of output generated during the scanning thereby generating two or more segments of the output. The method also includes separately detecting outliers in the two or more segments of the output. In addition, the method includes detecting defect candidates on the specimen by applying one or more predetermined criteria to results of the separately detecting to thereby designate a portion of the detected outliers as the defect candidates.
Patent WO-2021211106-A1 (WO)
Title: Coated substrates for electronic devices
Inventor: CHANG CHI HAO
IPC: G06F1/16
Filed: 2020-04-15
Abstract: A coated substrate for an electronic device can include a substrate, a physical vapor deposition layer over the substrate, and an anti-fingerprint layer over the physical vapor deposition layer. The physical vapor deposition layer can include an alloy of gold and platinum. The anti-fingerprint layer can include an ultraviolet radiation-cured polymer mixed with an anti-fingerprint material. The anti-fingerprint material can include a silane, a fluorinated polymer, a hydrophobic polymer, or a combination thereof.
Patent WO-2020219404-A1 (WO)
Title: Syringe for detecting pressure change
Inventor: LI-YU LIN
IPC: A61M5/20
Filed: 2020-04-21
Abstract: The invention provides a syringe for detecting pressure change. The syringe includes a barrel defining a reservoir for receiving a constituent, a piston movable within the reservoir and a plunger. The barrel further includes a proximal and a distal end with an outlet, an engaging member with a pair of fingers formed on an outer periphery of the barrel and a rib extending from the outer periphery of the barrel, disposed proximally to the engaging member. The plunger includes a first and second plunger part and a baseplate supporting the first and second plunger parts. The first plunger part is partially received by the reservoir and slidably engaged with the piston. The second plunger part further includes at least one stop ledge on the periphery of the second plunger part to which the fingers of the engaging member releasably latch, and a compartment for a first biasing member with first and second ends which engage with the rib and the baseplate respectively.
Patent WO-2020263389-A1 (WO)
Inventor: KOLOURI SOHELL
IPC: G06F21/57
Filed: 2020-04-21
Abstract: L'invention concerne un système de détection d'attaques par porte dérobée dans les réseaux neuronaux profonds à convolution (CNN). Le système compile des spécifications d'un CNN pré-entraîné en un modèle exécutable, ce qui se traduit par un modèle compilé. Un ensemble de motifs révélateurs universels (ULP) est passé à travers le modèle compilé, ce qui se traduit par un ensemble de sorties de modèle. L'ensemble de sorties de modèle est classifié et utilisé pour déterminer la présence d'une attaque par porte dérobée dans le CNN pré-entraîné. Le système exécute une réponse en fonction de la présence de l'attaque par porte dérobée.
Patent WO-2020219870-A1 (WO)
Inventor: SIMPSON BRYAN
IPC: A61K48/00
Filed: 2020-04-24
Abstract: CRISPR/Cas9-mediated genome editing holds clinical potential for treating genetic diseases, such as spinocerebellar ataxia type 2, which is caused by mutations in the ATXN2 gene. Here, compositions and methods for the treatment of spinocerebellar ataxia type 2 are provided. In some embodiments, a composition providing a vector encoding a guide RNA of the disclosure and a vector encoding a Cas9 protein or nuclease domain thereof of the disclosure are provided for use in the treatment of spinocerebellar ataxia type 2.
Patent WO-2020227642-A1 (WO)
Inventor: HANSSON KENNY MIKAEL
IPC: A61K38/39
Filed: 2020-05-08
Abstract: This disclosure relates to mRNA therapy for (i) the promotion and/or improvement of wound healing, (ii) the prevention and/or reduction of scar formation at a wound, (iii) the reduction of the visibility of a scar, and/or (iv) the treatment of epidermolysis bullosa. mRNAs for use in the invention, when intradermally (e.g., using microneedles) or topically administered  in vivo , encode a wound healing polypeptide (e.g., a growth factor, a cytokine, a chemokine, a protease inhibitor, or a collagen).
Patent WO-2020243414-A1 (WO)
Inventor: PAHKALA JANNE
IPC: H03L7/06
Filed: 2020-05-29
Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to bypass sensed signals in power converters. The disclosed methods, apparatus, systems and articles of manufacture provide an apparatus to bypass sensed signals in power converters, the apparatus comprising: a first single shot circuit to, during runtime of a power converter, generate a clock signal based on an adaptive delay, the adaptive delay based on a count value of a counter (526); a pulse comparator (514) coupled to an adaptation pulse generator, the pulse comparator (514) to, during runtime of the power converter: compare a first duration of the adaptation pulse to a second duration of a reference pulse; and adjust the count value of the counter (526); and a ready detector (542) coupled to the pulse comparator (514), the ready detector (542) to, in response to a trigger event, transmit, during runtime of the power converter, the count value to a second single shot circuit.
Patent WO-2020263659-A1 (WO)
Title: Filtres d'ondes acoustiques à échelle divisée
Inventor: MCHUGH SEAN
IPC: H03H9/60
Filed: 2020-06-17
Abstract: L'invention concerne des dispositifs à filtre et des procédés de fabrication de dispositifs à filtres. Le dispositif à filtre comprend une première puce et une seconde puce. La première puce comporte un premier empilement de matériau et contient un ou plusieurs résonateurs en série d'un circuit à filtre en échelle. La seconde puce comporte un second empilement de matériau et contient un ou plusieurs résonateurs en dérivation du circuit à filtre en échelle. Le premier empilement de matériau et le second empilement de matériau sont différents.
Patent WO-2021003092-A1 (WO)
Inventor: HUSKEY MERRIE MICHELLE
IPC: E21B43/10
Filed: 2020-06-29
Abstract: A production string and method of preventing accumulation of a compositional material in a production string. An inhibitor strip is disposed in a fluid inflow device of the production string. Fluid is received at the inhibitor strip in the fluid inflow device from a formation. The inhibitor strip includes a chemical inhibitor that interacts with a chemical in the fluid to reduce the production of the compositional material in the production string.
Patent WO-2021003480-A1 (WO)
Inventor: ZHANG XIAOWEI
IPC: G01N31/22
Filed: 2020-07-06
Abstract: An electrochemical aptamer-based (E-AB) sensor is disclosed. The sensor is a closed bipolar electrode having a first end and a second end. The first end comprises an electrochromic material. The second end comprises an electrocatalyst and an oligonucleotide aptamer tethered to the second end. Further, the oligonucleotide aptamer is labelled with a redox indicator.
Patent WO-2022019922-A1 (WO)
Title: Transmission power control
Inventor: LAGNADO ISAAC
IPC: H04W52/22
Filed: 2020-07-24
Abstract: In some examples, an electronic device comprises a wireless transceiver to transmit a packet and a processor coupled to the wireless transceiver. The processor is to update a running average of a radiation level over a time period. The running average is based on a quantity of packets transmitted by the wireless transceiver during the time period and a radiation level associated with the quantity of packets. The processor is to determine whether the running average exceeds a threshold and to control transmission power for the packet based on the determination and based on a destination of the packet.
Patent WO-2021050295-A1 (WO)
Title: Interactive display system with multifunctional privacy switch
Inventor: BRISTOL PETER WESLEY
IPC: H04M1/725
Filed: 2020-08-28
Abstract: An interactive display system may include (i) a housing surrounding at least a portion of a display region, (ii) a camera for capturing images via a camera opening defined in the housing, (iii) a microphone for capturing audio content, and (iv) a privacy switch assembly including a sliding member that is movable between a plurality of set positions. The plurality of set positions may include (i) a first position at which a field of view of the camera is unobstructed and the microphone is active, (ii) a second position at which a shutter of the privacy switch assembly blocks the field of view of the camera or the microphone is disabled, and (iii) a third position at which the shutter blocks the field of view of the camera and the microphone is disabled. Various other systems, devices, assemblies, and methods are also disclosed.
Patent WO-2021042028-A1 (WO)
Inventor: TANNU SWAMIT S
IPC: G06N99/00
Filed: 2020-08-31
Abstract: L'invention concerne un procédé de calcul quantique comprenant : la réception d'instructions de programme ; l'exécution des instructions de programme sur une machine quantique pour une pluralité d'essais afin de générer une pluralité de résultats ; la combinaison de la pluralité de résultats de l'exécution pour chaque essai de la pluralité d'essais ; et la détermination d'un résultat de programme de l'exécution sur la base de la combinaison de la pluralité de résultats.
Patent WO-2021046366-A1 (WO)
Title: Autonomous operations in oil and gas fields
Inventor: KRISTENSEN MORTEN
IPC: E21B47/005
Filed: 2020-09-04
Abstract: The present disclosure relates to a system that is operable to receive an execution plan and execute a control operation on one or more equipment based operations within the execution plan. The one or more operations may include a data capturing operation associated with a resource site. In one embodiment, the system may be operable to execute at least a first operation in response to a success variable of the data capturing operation indicating a successful execution of the data capturing operation. The first operation may include a quality control operation that is executed by comparing at least one characteristic of the captured data to an expected characteristic to generate quality state data. The quality state data may have one of an acceptable status and an undesirable status. In response to the quality state data indicating an acceptable status for the quality control operation, executing at least a second operation.
Patent WO-2021061947-A1 (WO)
Inventor: GALEOTTI JOHN
IPC: G06K9/00
Filed: 2020-09-24
Abstract: L'invention concerne un système, un procédé et un produit programme d'ordinateur pour l'analyse d'images médicales spatiotemporelles à l'aide d'un réseau neuronal artificiel. Le procédé comprend la capture d'une série d'images médicales d'un patient, la série d'images médicales comprenant un mouvement visuel d'au moins une entité, le suivi de données spatiales variant dans le temps associées à la ou aux entités sur la base du mouvement visuel, la génération de données spatiotemporelles par corrélation des données spatiales variant dans le temps avec la série d'images médicales, et l'analyse de la série d'images médicales sur la base d'un réseau neuronal artificiel comprenant une pluralité de couches, une ou plusieurs couches de la pluralité de couches combinant, chacune, des caractéristiques tirées d'au moins trois échelles différentes, au moins une couche de la pluralité de couches du réseau neuronal artificiel étant configurée pour apprendre des relations spatiotemporelles sur la base des données spatiotemporelles.
Patent WO-2021076480-A1 (WO)
Inventor: SHIFLETT MARK BRANDON
IPC: C07C19/03
Filed: 2020-10-13
Abstract: Processes for separating an azeotropic mixture are provided. In an embodiment, such a process comprises exposing an azeotropic mixture comprising a first (hydro)fluorocarbon and a second (hydro)fluorocarbon to an ionic liquid comprising a cation and a non-fluorinated anion at a temperature and a pressure at which the ionic liquid absorbs more of one of the first and second (hydro)fluorocarbons than another of the first and second (hydro)fluorocarbons as determined on a mass basis to form a (hydro)fluorocarbon-containing ionic liquid and a processed azeotropic mixture.
Patent WO-2021108280-A1 (WO)
Title: Système et procédé de fonctionnement de dispositifs de régulation de débits entrants
Inventor: AL-QUWAISIM HUSSAIN
IPC: E21B23/00
Filed: 2020-11-21
Abstract: Dispositif de régulation de débits entrants (« ICD ») (26) dans une colonne de production (34) d'un puits de forage (10) qui est utilisé pour réguler un flux de fluide à travers l'ICD (26). L'ICD (26) peut être ajusté en réponse à une force externe qui est sélectivement appliquée par un actionneur (65) qui comprend un ensemble à logement inférieur (« BHA ») (50). Le BHA (50) est déployé sur un tube spiralé (32) et ancré dans le puits de forage (10) pour isoler le tube spiralé (32) de forces résultantes ou de contre-forces générées lors de l'ajustement de l'ICD (26). Le fluide est éventuellement injecté dans le tube spiralé (32) en surface et dirigé dans le puits de forage à partir du BHA (50). L'actionneur (65) comprend un bras (54) de verrouillage. L'actionneur est équipé d'un profil (58) qui correspond à un profil (60) sur l'ICD (26) pour faciliter l'enclenchement entre le bras (54) et l'ICD (26).
Patent WO-2021108478-A1 (WO)
Inventor: KIDAMBI PIRAN RAVICHANDRAN
IPC: H01M4/92
Filed: 2020-11-25
Abstract: Disclosed herein are proton transport membranes and methods of making and use thereof. The proton transport membranes comprise: a two-dimensional (2D) material having a top surface and a bottom surface; wherein the two-dimensional material comprises graphene and hexagonal-boron nitride in an atomic ratio of from 100:0 to 0:100. In some examples: the top surface is functionalized with a first functional moiety and the bottom surface is not functionalized; the top surface is functionalized with a first functional moiety and the bottom surface is functionalized with the first functional moiety; or the top surface is functionalized with a first functional moiety and the bottom surface is functionalized with a second functional moiety, the second functional moiety being different than the first functional moiety. In some examples, the two-dimensional material is doped with a substitutional dopant in an amount of from greater than 0 atomic% (at%) to less than 100 at%.
Patent WO-2021113624-A1 (WO)
Inventor: GONZALEZ RICARDO ALONSO
IPC: F24F11/52
Filed: 2020-12-04
Abstract: In some examples, a device includes an analog display configured to indicate a current temperature and one or more temperature set points. Additionally, the device includes processing circuitry is configured to control a set of light-emitting diodes (LEDs) to emit one or more optical beams to reflect off of a projection ring onto the analog display. The one or more optical beams are a first color if the current temperature is lower than a set point temperature of the one or more set point temperatures. The one or more optical beams are a second color if the current temperature is greater than the set point temperature of the one or more set point temperatures.