baber/WOPTO huggingface dataset:
Patent CA-3007565-A1 (CA)
Inventor: MONTEMAGNO CARLO
IPC: A61K9/50
Filed: 2018-06-07
Abstract: Smart pH-sensing microencapsulation system programmed to actively respond to environmental pH change has long been considered a key technology in pharmaceutical industries and food sciences. Maintenance of both stability of active materials in harsh gastrointestinal (GI) tract environments and release at target site-specific pH is a major obstacle in oral drug/vaccine development. In this study, we developed a first-of-its-kind drug delivery system with pH-responsive macropores. Opening and closing of these macropores depend on pH  to meet the critical requirements of intestine-targeted drug delivery system, providing stability in stomach and rapid release in intestine. To this end, we developed pored hollow microparticles (MPs) made of anionic copolymer using an Oil-in-Water (O/W) emulsion method. We observed that freeze-drying of MPs induced closure of macropores on their surface, probably due to the decrease of glass transition temperature via surfactant incorporation and/or physicochemical characteristics of polymer-water and polymer-polymer interaction during dehydration process.  The closing and opening behavior of the sealed macropore on MPs in response to pH change were confirmed after being subjected to simulated gastric pH (2-hr incubation at pH 2.0) and intestinal pH (4-hr incubation at pH 7.1), respectively. Time dependent release behavior of ingredients through pH-sensing pores was tested using two different types of model drugs (sulforhodamine b and 100 nm sized fluorescent nanoparticles). The intact, closed structure of the dye-encapsulated macropore was maintained in simulated gastric environment. Subsequent exposure of the same sample to simulated intestine environment induced pore opening, which caused release of the ingredients from MPs. To demonstrate the applicability of our microencapsulation system for active biomolecules, lactase enzymes were encapsulated in MPs.  Theses MPs displayed more than 15 times higher protections than commercial lactase formulations, indicating the protective activity of the MP system against harsh GI conditions.  This study showed that taking mutual advantages of solid and hollow architectures, microparticles with a pH-responsive macropore exhibited easy solvent-free loading and protection of ingredients in unfavorable pH by closing pores, and triggered their release in targeted pH by opening pores. Ultimately, our MP system with a pH-sensing macropore strives to usher a new area of research in smart drug delivery systems and advance the current oral drug delivery technology by solving major challenges in targeted delivery of pH-sensitive therapeutic agents.
Patent CA-3007890-A1 (CA)
Inventor: DIHORA JITEN ODHAVJI
IPC: A61K8/11
Filed: 2017-01-04
Abstract: Microcapsule slurries can be formed from a phosphate ester and a multivalent ion. The microcapsules can encapsulate a core material misicible with the phosphate ester. The phosphate ester can be lipophilic and insoluble in aqueous solutions.
Patent CA-3008263-A1 (CA)
Title: Wireless charging system for smartdevices, kit and method for using the same
Inventor: DESHAIES PATRICK
IPC: H02J7/00
Filed: 2018-06-13
Abstract: A charging system for wirelessly charging a smartdevice positioned over the charging system is disclosed. The system has a charger connectable to an electrical power source for charging the smartdevice and can be inserted inside a furniture through an opening located at its top surface; a fixing element compatible with the opening and affixed to the charger for maintaining the charger fixably engaged inside the opening below the top surface; and a removable cap for capping the fixing element. When the removable cap is made of a transparent material, the charging system further comprises an advertising message presented on a support affixed to the bottom surface of the transparent cap, the message being then visible through the transparent cap. Alternatively, the top surface of the removable cap comprises the advertising message. Advantageously, the system enhances replaceability of the advertising message.
Patent CA-3008635-A1 (CA)
Title: Procede d'infusion de resine pour la fabrication de composites renforces par des fibres
Inventor: MEEGAN JONATHAN EDWARD
IPC: B29C48/475
Filed: 2016-12-15
Abstract: L'invention concerne un procédé d'infusion de résine qui incorpore une approche de fusion à la demande. Le procédé comprend : (a) l'utilisation d'une composition de résine durcissable sous la forme d'un bloc de résine congelée (20) ; (b) la liaison du bloc de résine congelée (20) à un orifice d'entrée d'une extrudeuse chauffée (22), qui comprend au moins une vis rotative (24) logée à l'intérieur d'un cylindre chauffé (25) ; (c) la fusion progressive du bloc de résine congelée (20) au niveau de l'orifice d'entrée et l'introduction concomitante de la résine fondue dans le cylindre chauffé (25) pour produire une résine liquide ayant une viscosité appropriée pour l'infusion de résine ; (d) l'introduction en continu de la résine liquide sortant de l'extrudeuse dans un moule, qui contient une préforme fibreuse ; et (e) l'introduction de la résine liquide dans la préforme fibreuse, le bloc de résine congelée (20) fournissant une quantité de composition de résine suffisante pour l'infusion de toute la préforme fibreuse.
Patent CA-3011166-A1 (CA)
Title: Sterilization device and methods
Inventor: TAGGART DANIEL
IPC: A61L2/22
Filed: 2017-01-13
Abstract: A portable sterilization device comprises: an external housing unit; a sealable sterilization chamber located within the external housing unit; a sterilant delivery device comprising a nebulization element and one or more sterilants, wherein the nebulization element is configured to convert the sterilants into an oxidative aerosol sterilant and deliver the oxidative aerosol sterilant into the sterilization chamber; an ozone delivery device configured to deliver ozone into the sterilization chamber; an airflow circulation assembly; a control panel; and a power source operatively associated with the control panel. The control panel is configured to execute an operation to provide simultaneous delivery of the oxidative aerosol sterilant and the ozone into the sterilization chamber. The sterilization device and method address an unmet need for sterilizing surgical equipment in emergency medical situations in remote locations where modem sterilization equipment is not available.
Patent CA-3011716-A1 (CA)
Inventor: ALLOTT MARK T
IPC: B01D35/147
Filed: 2017-01-18
Abstract: La présente invention concerne un élément de filtre (16) qui peut comprendre un élément tubulaire (26) définissant un espace interne (32), et un élément de retenue (34) associé à une première extrémité (28) de l'élément tubulaire (26), l'élément de retenue (34) étant configuré de manière à être couplé à un premier boîtier (14). L'élément de filtre (16) peut comprendre en outre un élément de siège de vanne (36) dans l'espace interne (32). L'élément de siège de vanne (36) peut comprendre une ouverture de siège de vanne (38) configurée pour former un joint d'étanchéité aux fluides avec un clapet de vanne (40). L'élément de filtre (16) peut comprendre en outre des premier et deuxième bouchons (42, 46) associés aux extrémités (28, 30) de l'élément tubulaire (26). L'élément de filtre (16) peut comprendre en outre un milieu filtrant (50) autour de l'élément tubulaire (26), et le deuxième bouchon (46) peut être configuré pour former un joint d'étanchéité aux fluides (76) entre l'élément de filtre (16) et un passage de drainage (24) dans un deuxième boîtier (18), de sorte que, lorsque l'élément de filtre (16) est séparé du deuxième boîtier (18), le fluide s'écoule depuis l'élément de filtre (16) dans le passage de drainage (24).
Patent CA-3013655-A1 (CA)
Title: Procede et dispositif de codage/decodage d'image
Inventor: CHEN HUANBANG
IPC: H04N19/52
Filed: 2016-09-08
Abstract: L'invention concerne un procédé et un dispositif de codage/décodage d'image permettant d'améliorer la précision de codage/décodage. Le procédé consiste à : déterminer, en fonction d'une première règle prédéfinie, N unités codées parmi des unités codées adjacentes d'une unité à coder, un mode de prédiction de mouvement des N unités codées étant identique à celui de l'unité à coder ; générer, en fonction d'un vecteur de mouvement d'une nième unité codée, un nième groupe de vecteurs de mouvement à l'aide d'un premier algorithme prédéfini, n traversant l'ensemble des entiers positifs ne dépassant pas N ; déterminer, à partir de N groupes de vecteurs de mouvement obtenus en fonction d'une seconde règle prédéfinie, un groupe de vecteurs de mouvement en tant que groupe de vecteurs de mouvement optimal ; déterminer, en fonction du groupe de vecteurs de mouvement optimal, une règle de pixel prédite de chaque unité de pixel dans l'unité à coder au moyen d'un second algorithme prédéfini ; et coder une valeur résiduelle prédite de chaque unité de pixel et un ID d'indice du groupe de vecteurs de mouvement optimal pour obtenir un flux correspondant à l'unité à coder.
Patent CA-3013815-A1 (CA)
Title: Activation de carte securisee sur une option de fichier destinee a des applications marchandes electroniques
Inventor: PURVES THOMAS
IPC: G06Q20/08
Filed: 2017-03-17
Abstract: La présente invention peut autoriser un utilisateur à transférer des données sur une carte de transaction qui a été entrée dans une application de paiement afin d'être "sur un fichier" avec un marchand. Ainsi, le consommateur n'a pas à entrer une information de paiement électronique à nouveau comme la donnée est transférée de l'application de paiement à l'application marchande où la carte est ensuite maintenue sur un fichier.
Patent CA-3014117-A1 (CA)
Title: Pinhole-spy-camera and car-antenna assembly
Inventor: SZKODZINSKI ANDRZEJ
IPC: B60R11/04
Filed: 2018-08-14
Abstract: The invention is an assembly comprising a car antenna and a pinhole camera where said pinhole camera is positioned in the tip of said car antenna, and said camera transmits live video to a display device inside the vehicle for live viewing by the driver and/or passenger(s). The antenna/camera assembly is mounted to the roof of a car, and in all respects resembles an inconspicuous car antenna. A miniature pinhole camera (or spy-camera) is positioned/hidden in the tip of the car antenna and the pinhole camera is pointed in the forward direction of the vehicle. The miniature size of the pinhole camera makes the camera position visually inconspicuous and thus ideal for adaptation to vehicle design or stealth/spying or surveillance applications. The use of the car antenna shaft as a vertical support structure for the camera makes the invention low cost, easily to integrate with vehicle design and ideal for adoption by the global automotive industry.
Patent CA-3015122-A1 (CA)
Inventor: GUPTA ASHISH
IPC: E04H12/34
Filed: 2018-08-23
Abstract: A method of building and operating a land-based drilling rig with a high-capacity mast include providing a platform collapsed on a substructure over a proposed well drilling location and building the high-capacity mast in a horizontal condition by attaching a lower portion of the high-capacity mast to the platform. The high-capacity mast having an opening formed therein sized to accommodate four Range 2 pipes or three Range 3 pipes. The high-capacity mast may be raised from the horizontal condition to a vertical condition by pushing the side of the high-capacity mast to pivot the high-capacity mast about a pivot point on the platform. The platform may be raised from a collapsed condition to a raised condition over the substructure. Some implementations include dual racking boards on the high-capacity mast.
Patent CA-3017029-A1 (CA)
Title: Microwave-assisted medical technologies and apparatus therefor
Inventor: BELANGER JACQUELINE M R
IPC: A61N5/02
Filed: 2017-04-05
Abstract: There is disclosed a method of treating affected external or surface tissue comprising the steps of providing a source of affected external or surface tissue; generating a source of microwave energy; transmitting said microwave energy into said affected external or surface tissues; exposing said affected external and surface tissues to said microwave energy to raise the local temperature to thereby ablate, remove, coagulate or otherwise alter said affected external and surface tissues. There is also disclosed an apparatus for the treatment of affected external and surface tissues comprising a microwave energy source generator, a means to transmit said microwave energy into said affected external or surface tissues, a means to control the exposure of said affected external and surface tissues to said microwave energy to raise the local temperature to thereby ablate, remove, coagulate or otherwise alter said affected external and surface tissues; and optionally a means to control the repetition of steps a) to d) multiple times until the ablation, removal, coagulation or otherwise alteration is complete, the period between each sequence of steps a) to d) being optionally cooled, and the location of said concentrated electric field being varied.
Patent CA-3017503-A1 (CA)
Inventor: SCHULTER DREW
IPC: A61C5/00
Filed: 2017-03-10
Abstract: A dental prosthesis and a process for design and manufacturing, incorporating a dental implant framework and veneering overlay that will be designed and manufactured simultaneously and permanently fixated to one another.
Patent CA-3021300-A1 (CA)
Title: Cooking apparatus and method of using the cooking apparatus
Inventor: BLOND LAURENT
IPC: A47J36/32
Filed: 2017-04-28
Abstract: Cooking apparatus (A) comprising a cooking system (SYS) exhibiting a cooking site, a communication unit (UC) able to exchange information with a remote terminal (T) according to a communication protocol, the communication unit (UC) being designed to receive a cooking parametrization information item (ipc) comprising a set of coefficients (C1, C2,, Cn), a control and command unit (CC) for the cooking system (SYS) comprising a processor (P) designed to regulate a cooking temperature according to a cooking setpoint. The control and command unit (CC) is designed to be disposed in a first configuration in which the said cooking setpoint is dependent on the selected category of food, or alternatively in a second configuration in which the said cooking setpoint is dependent on the set of coefficients (C1, C2,, Cn) received by the communication unit (UC).
Patent CA-3021939-A1 (CA)
Inventor: GOODELL DAVID J
IPC: F16D65/10
Filed: 2018-10-24
Abstract: A brake drum usable in a vehicle includes a substantially cylindrical wall having an end surface at one axial end thereof, with the substantially cylindrical wall defining a radially inwardly facing wear surface to be engaged by a friction lining upon brake actuation during operation of the vehicle. A radially extending drum section is joined by way of a corner section to another axial end of the substantially cylindrical wall and, together with the substantially cylindrical wall and the corner section, forms a drum interior volume. To provide for discharge of particles from the drum interior volume, the substantially cylindrical wall has a circumferentially extending cut away section in the wear surface located adjacent to the one axial wall end.
Patent CA-3023846-A1 (CA)
Title: Element de boitier et procede de fabrication de cet element
Inventor: WINKLER SEBASTIAN
IPC: A61N1/375
Filed: 2017-05-11
Abstract: Élément de boîtier, destiné en particulier à des dispositifs implantables, comprenant au moins une partie de paroi de boîtier qui présente une ouverture de type fenêtre pour le passage d'ondes électromagnétiques, cette ouverture étant fermée hermétiquement par formage d'une ébauche constituée d'un matériau perméable aux ondes électromagnétiques.
Patent CA-3026728-A1 (CA)
Title: Schemas posologiques de la vortioxetine destines a une apparition rapide de l'effet antidepresseur
Inventor: MORILLO CONNIE SANCHEZ
IPC: A61P25/24
Filed: 2017-06-28
Abstract: L'invention concerne un schéma posologique comprenant l'administration simultanée de deux compositions pharmaceutiques, la première composition pharmaceutique étant une composition comprenant de la vortioxétine ou un sel de qualité pharmaceutique de cette dernière, pour une administration quotidienne unique par voie orale, et la seconde composition pharmaceutique étant une composition comprenant de la vortioxétine ou un sel de qualité pharmaceutique de cette dernière, qui, associée à ladite première composition, permet d'atteindre rapidement une concentration plasmatique stable de vortioxétine chez ledit patient, ladite concentration plasmatique stable étant identique à la concentration plasmatique stable de vortioxétine obtenue par l'administration audit patient de ladite première composition seule.
Patent CA-3029435-A1 (CA)
Inventor: THOMAS MATHILDE
IPC: A61K8/9789
Filed: 2016-09-12
Abstract: The invention relates to a composition for topical application containing at least one combination of (a) polyphenols selected from proanthocyanidin monomers and oligomers (OPC), hydroxystilbenes, flavonoid monomers and oligomers, and derivatives and mixtures thereof, (b) a spruce extract comprising at least one lignan selected from: hydroxymatairesinol, secoisolariciresinol, conidendrin, lariciresinol and liovile. It also relates to the cosmetic use of such a combination for combating the signs of ageing of the skin or hair and nails or the effects of pollution, and a cosmetic treatment method using said combination.
Patent CA-3029817-A1 (CA)
Inventor: WANG YINGJIE
IPC: C12Q1/68
Filed: 2019-01-11
Abstract: The invention relates to the canola variety SCV528587. Provided by the invention are the seeds, plants, plant parts and plant cells of the canola variety SCV528587. Also provided by the invention are methods for producing canola plants by crossing the canola variety SCV528587 with itself or another canola variety and plants produced by such methods.
Patent CA-3031425-A1 (CA)
Inventor: SLASSI ABDELMALIK
IPC: A61K31/538
Filed: 2016-10-31
Abstract: The present application relates to novel heterocycle derivatives of Formula (I), to processes for preparing them, pharmaceutical compositions containing them, and their use thereof in the treatment or prevention of acute and/or chronic neurological disorders such as psychosis, epilepsy, schizophrenia, Alzheimer' disease, cognitive disorders and/or memory deficits, as well as chronic and acute pain and other related CNS disorders.
Patent CA-3032024-A1 (CA)
Title: Application de conducteurs electriques sur un substrat electriquement isolant
Inventor: LANDA BENZION
IPC: H05K3/20
Filed: 2017-07-28
Abstract: L'invention concerne un procédé d'application d'un conducteur électrique sur un substrat électriquement isolant, qui consiste à utiliser une membrane flexible avec un motif de rainure formé sur une première surface de celle-ci, à charger les rainures avec une composition comprenant des particules conductrices. La composition est ou peut être rendue électriquement conductrice. Une fois la membrane chargée, la première surface rainurée de la membrane est mise en contact avec l'avant et/ou l'arrière du substrat. Une pression est ensuite appliquée entre le substrat et la membrane de sorte que la composition chargée dans les rainures adhère au substrat. La membrane et le substrat sont séparés et la composition dans la rainure est laissée sur la surface du substrat électriquement isolant. Les particules électroconductrices de la composition sont ensuite frittées pour former un motif de conducteurs électriques sur le substrat, le motif correspondant au motif formé dans la membrane.
Patent CA-3032703-A1 (CA)
Title: Method of information provision and electric carrier system
Inventor: LU CHUN-TING
IPC: B60L58/10
Filed: 2019-02-01
Abstract: A method of information provision is implemented by an electric carrier system which includes an electric carrier device storing a carrier identifier and carrier information, a power supply device providing electrical energy to the electric carrier device, and storing reference carrier identifiers and battery information, and an electronic device communicable with the electric carrier device and a server. The method includes : by the electric carrier device when in communication with the electric device, transmitting to the electronic device, integrated information including the carrier and battery information; and by the electronic device which is in communication with the server, transmitting the integrated information to the server.
Patent CA-3033121-A1 (CA)
Title: Metallurgical vessel lining with enclosed metal layer
Inventor: JANSSEN DOMINIQUE
IPC: B22D41/02
Filed: 2017-08-16
Abstract: A lining structure 30 for a refractory vessel contains a first layer 34; a second layer 42, in communication with the first layer, containing a metal layer or component; and a third layer 50, in communication with the second layer 42. The metal component 64 in the second layer may contain filled transverse passages, between the surface of the second layer in contact with the first layer 44 and the surface of the second layer in contact with the third layer 46, producing support structures 68 to maintain the structural integrity of the refractory vessel in use.
Patent CA-3033486-A1 (CA)
Title: Method of detecting pre-fire situations arising as a result of electrical circuit faults
Inventor: LESIV ALEKSEY VALERYEVICH
IPC: G08B17/08
Filed: 2016-08-10
Abstract: The present invention relates to the field of fire safety and electrical engineering, and more particularly to methods of detecting pre-fire situations arising as a result of the local overheating of electrical equipment, and is intended for preventing fires caused by electrical wiring faults, particularly faults in wiring devices. The claimed method is based on measuring the amount of low-boiling substances in the atmosphere of a protected space, said substances being contained in capsules which have a rupture temperature in a range of 80-200ºC and which are fastened to current-carrying components. If said components reach a corresponding temperature, the capsules rapture, causing the substances to be released into the environment. The technical result of the claimed invention is an increase in the likelihood of early detection of a pre-fire situation.
Patent CA-3033741-A1 (CA)
Inventor: VIJAYAN KANDASWAMY
IPC: C12Q1/68
Filed: 2017-08-15
Abstract: Provided are compositions, methods and systems for determining the sequence of a template nucleic acid using a polymerase-based, sequencing-by-binding procedure. An examination step involves monitoring the interaction between a polymerase and template nucleic acid in the presence of one or more nucleotides. Identity of the next correct nucleotide in the sequence is determined without incorporation of any nucleotide into the structure of the primer by formation of a phosphodiester bond. An optional incorporation step can be used after the examination step to extend the primer by one or more nucleotides, thereby incrementing the template nucleotides that can be examined in a subsequent examination step. The sequencing-by-binding procedure does not require the use of labeled nucleotides or polymerases, but optionally can employ these reagents.