baber/WOPTO huggingface dataset:
Patent CA-2262668-C (CA)
Title: Inhibitors of cathepsin k
Inventor: VEBER DANIEL F
IPC: A61P31/12
Filed: 1997-08-07
Granted: 2006-05-09
Abstract: This invention relates to compounds of formula (I), wherein A is C(O) or CH(OH); R1 is (1), (2), (3) or (4); R2 is H, C1-6alkyl, C3-6cycloalkyl-C0-6alkyl, Ar-C0-6alkyl, Het-C0-b6alkyl, R5C(O)-, R5C(S)-, R5SO2-,~R5OC(O)-, R5R'NC(O)-, R5R'NC(S)-, adamantyl-C(O)-, or (5); R'' is H, C1-6alkyl, Ar-C0-6alkyl, or Het-C0-6alkyl; R''' is H, C2-6alkyl, C3-6cycloalkyl-C0-6alkyl, Ar-C0-6alkyl, or Het-C0-6alkyl; each R3 independently is H, C2-6alkenyl, C2-6alkynyl, Het, Ar or C1-6alkyl op-tionally substituted by OR', SR', NR'2, R'NC(O)OR5, CO2R', CO2NR'2, N(C=NH)NH2, Het or Ar; R4 is H, C1-6alkyl, C3-6cycloalkyl-C0-6alkyl, Ar-C0-6alkyl, Het-C0-6alkyl, R5C(O)-, R5C(S)-, R5SO2-, R5OC(O)-,~R5R'NC(O)-, R5R'NC(S)-, R'HNCH(R')C(O)-, or R5OC(O)NR'CH(R')C(O)-; each R5 independently is C3-6cycloalkyl-C0-6alkyl, Ar-C0-6alkyl, Het-C0-6alkyl, Ar-C0-6alkoxy, Het-C0-6alkoxy, or C1-6alkyl option-ally substituted by OR', SR', NR'2, R'NC(O)OR5, CO2R', CO2NR'2, N(C=NH)NH2, Het or Ar; R6 is H, C1-6alkyl, Ar-C0-6alkyl, or Het-C0-6alkyl and R7 is H, C1-6alkyl, C3-6cycloalkyl-C0-6alkyl, Ar-C0-6alkyl, Het-C0-6alkyl, R5C(O)-, R5C(S)-, R5SO2-, R5OC(O)-, R5R'NC(O)-, R5R'NC(S)-, R'HNCH(R')C(O)-, or R5OC(O)NR'CH(R')C(O)-; or R6 and R7 are connected to form a pyrrolidine, a piperidine, or a morpholine ring; each R' independently is H, C1-6alkyl, Ar-C0-6alkyl, or Het-C0-6alkyl; R* is H, C1-6alkyl, C3-6cycloalkyl-C0-6alkyl, Ar-C0-6alkyl, or Het-C0-6alkyl; Y is a single bond or O; each Z independently is CO or CH2; and n is 0, 1, or 2; or a pharmaceutically acceptable salt thereof, which are inhibitors of cysteine proteases, particularly cathepsin K, and are useful in the treatment of diseases in which inhibition of bone loss is a factor.
Patent CA-2263381-C (CA)
Inventor: BODIN JAN-OLOF
IPC: E05B65/19
Filed: 1997-08-15
Granted: 2005-10-18
Abstract: A hood and fender assembly mounting and latch system for use with a pivotally mounted hood and fender assembly (42) of an over-the-highway tractor. A hex shaped torsion bar and damper (312) is used to assist in the opening and closing of the hood and fender assembly. The latch system includes a receiver assembly (82) attached to the frame (22).  A pin assembly (162) is attached to the hood and fender assembly at a distal location relative to a hinge (44). The receiver assembly receives the pin assembly when the hood and fender assembly is in a position enclosing the engine. The receiver assembly has a lock lever (104) which is movable between a latched position at which it engages the pin assembly and an unlatched position. A cable (68) connects a handle (66) with the lock lever for moving the lock lever between the latched and unlatched positions.
Patent CA-2265557-C (CA)
Inventor: FIELDING STUART
IPC: A61H7/00
Filed: 1997-09-12
Granted: 2005-11-22
Abstract: Selon l'invention, on crée, chez l'homme, un effet analogue à l'effet de pincement de la queue, au moyen d'un appareil permettant d'appliquer une pression variable localisée à la colonne vertébrale. La pression appliquée peut être commandée manuellement, par télécommande et/ou automatiquement. Une application sélective de la pression peut susciter un nombre de changements chez l'homme, par exemple une augmentation de l'appétit, un changement du comportement sexuel, une augmentation du flux sanguin allant au cerveau, et/ou une augmentation de la sécrétion de neurotransmetteurs, y compris de la dopamine, de la sérotonine et de la noradrénaline. Cet effet est utile pour le traitement de la maladie de Parkinson, des troubles dépressifs, des accidents cérébro-vasculaires et d'autres états pathologiques.
Patent CA-2265842-C (CA)
Inventor: NICHOLS KATHLEEN M
IPC: H04N21/2381
Filed: 1997-06-30
Granted: 2005-08-09
Abstract: Bi-directional communications system in a CATV network utilizing cell-based Asynchronous Transfer Mode (ATM) transmissions. Packet data existing in any one of several different formats are first converted into ATM cells by a headend controller. Individual cells are then assigned a virtual connection by the headend controller. Based on the virtual connection, the cells can be prioritized and routed to their intended destinations. The cells are transmitted in a shared radio frequency spectrum over a standard cable TV network. A subscriber terminal unit demodulates the received RF signal and processes the cells for use in a computer. Likewise, computers may transmit packet data to their respective subscriber terminal units which are sent to the headend controller over the same CATV network. Hence, the present invention offers a flexible, effective, economic, and fully integrated multimedia bearer system granting immediate support for Internet services, traditional voice telephony, and digital video services over a CATV network.
Patent CA-2267676-C (CA)
Title: Procede de communication sans fil avec un appareil medical implante
Inventor: KOSLAR MANFRED
IPC: A61N1/372
Filed: 1997-11-03
Granted: 2003-05-13
Abstract: L'invention concerne un procédé de communication sans fil avec un appareil médical, notamment implanté dans le corps humain. Un signal d'entrée de message (S1, g4) est soumis à une modulation angulaire dans un émetteur (2 à 8, 16 à 26) puis envoyé à un récepteur (11 à 15, 29 à 37) par un canal de transmission. L'émetteur produit des impulsions à modulation angulaire, portant le message et présentant un spectre de fréquences, de telle manière que ces impulsions puissent subir une compression temporelle dans le récepteur (11 à 15, 29 à 37) au moyen d'un filtre dont le temps de transit est fonction de la fréquence, notamment d'un filtre de dispersion (13, 32, 33) pour obtenir des impulsions de durée réduite et d'amplitude élargie par rapport aux impulsions reçues. De plus, les impulsions émises par l'émetteur conservent au moins une partie des informations constituant le message après avoir subi une nouvelle modulation ou un nouveau codage de la technique des communications, et/ou au moins une partie des informations constituant le message est appliquée en plus de la modulation angulaire.
Patent CA-2270106-C (CA)
Title: Nucleic acid purification and process
Inventor: HAJ-AHMAD YOUSEF
IPC: C07H1/06
Filed: 1999-04-23
Granted: 2006-03-14
Abstract: The invention disclosed is particularly directed to a process for the purification of DNA, and is especially useful for the isolation of biologically active plasmid DNA. The process is initiated by binding the DNA to silicon carbide particles, either in the presence or absence of chaotropic agents. The bound DNA is subsequently eluted from the resin in low salt buffer or water. The resulting purified DNA is substantially free of proteins and is shown to be biologically active. The scope and diversity of the process is demonstrated here since this process can be used for the isolation of RNA and genomic DNA as well as the purification of PCR products and isolation of DNA from agarose gel slices.
Patent CA-2273992-C (CA)
Inventor: HARRIS JOHN J
IPC: B29C70/24
Filed: 1997-12-22
Granted: 2004-07-13
Abstract: An ultrasonic fastening system wherein an ultrasonic transducer (48) is used to insert a plurality of fasteners (12) supported by a compressible member (10) into two components (14, 16) to be joined or a single composite part to be reinforced.
Patent CA-2276335-C (CA)
Title: Nitride semiconductor device
Inventor: SENOH MASAYUKI
IPC: H01S5/32
Filed: 1998-01-08
Granted: 2006-04-11
Abstract: A nitride semiconductor device including a light emitting device comprises a n-type region of one or more nitride semiconductor layers having n-type conductivity, a p-type region of one or more nitride semiconductor layers having p-type conductivity and an active layer between the n-type region and the p-type region. In such devices, there is provided a super lattice layer comprising first layers and second layers which are nitride semiconductors having a different composition respectively. The super lattice structure makes working current and voltage of the device lower, resulting in realization of more efficient devices.
Patent CA-2277522-C (CA)
Inventor: MAJCHROWICZ MICHAEL
IPC: A63B59/14
Filed: 1999-07-16
Granted: 2005-06-28
Abstract: An articulated handle for hockey sticks. This articulated handle extends downwards and outwards from the top of the stick handle. The articulated handle is compound angled and forms a grip for the user. In use, the player holds the stick in one hand at about the center of the handle as before. The upper hand holds the articulated handle. The articulation creates a natural position for holding the stick.  Moreover, it gives the user considerably more power and control. Finally, the articulated handle reduces the stress placed on the user's wrist, thereby reducing or eliminating stress injuries. Although this handle is designed for use with hockey sticks, it can also be used on any handled implement, such as shovels, rakes, hoes, tennis rackets, or other similar implements.
Patent CA-2293562-C (CA)
Title: Single-source gas actuation for screw compressor slide valve assembly
Inventor: BEEKMAN DENNIS M
IPC: F25B49/02
Filed: 1998-06-18
Granted: 2004-10-12
Abstract: The position of a screw compressor slide valve in a refrigeration system is controlled using compressor discharge gas sourced from a location where the gas is relatively oil-free and has undergone little or no pressure drop subsequent to its discharge from the compressor's working chamber.
Patent CA-2299638-C (CA)
Inventor: MORIYASU SEI
IPC: B24B53/00
Filed: 2000-02-28
Granted: 2008-01-15
Abstract: A conductive grindstone 12, a circular disk-like discharge electrode 14 with an outer rim 14a that can access a machining surface 12a of the grindstone, an electrode rotating device 16, a position controlling device 18 that controls the relative position between the outer rim of the electrode and the grindstone, a voltage applying device 20 for applying voltage pulses between the grindstone and the electrode, and a mist-supplying device 22 that supplies pressurized conductive mist between the grindstone and the electrode are provided. The pressurized conductive mist is a mixture of a low-conductivity aqueous solution and compressed air. A plasma discharge is generated between the grindstone and the electrode by means of this pressurized conductive mist, and the grindstone is subjected to truing. In this way, grindstone essentricity and deflection can efficiently be removed, the grindstone does not deform, high-accuracy truing is achieved, the power supply can be compact with a small power output, no complicated control circuit or control device is needed, and consumable parts such as the electrode can easily be manufactured and remachined.
Patent CA-2299683-C (CA)
Inventor: DALLAS L MURRAY
IPC: E21B33/068
Filed: 2000-02-28
Granted: 2004-06-22
Abstract: A wellhead isolation tool permitting a high fluid flow rate during a well treatment to stimulate production is described. The wellhead isolation tool includes a mandrel to be inserted into a wellhead. The mandrel is sealed in a tubing hanger above back pressure valve threads to isolate the pressure sensitive components of the wellhead from fluid pressure used in the well treatment, and has a lower section extending past the back pressure valve threads and tubing threads into the tubing to protect the threads from washout. The mandrel is locked down with a mechanical lockdown mechanism having a broad range of adjustment. The advantages are that no special tubing hanger is required for use with the mandrel, and a fluid flow rate enabled by the tool during the well treatment is significantly higher than a fluid flow rate enabled with conventional wellhead isolation tools.
Patent CA-2302545-C (CA)
Inventor: MCCARTHY MICHAEL P
IPC: A61K47/48
Filed: 1998-08-19
Granted: 2012-04-03
Abstract: L'invention concerne une méthode de désassemblage-réassemblage de particules voroïdes du papillomavirus. Les VLP ainsi obtenues présentent une homogénéité accrue, ainsi que des épitopes de papillomavirus neutralisants, conformationnels, et constituent, par conséquent, des agents prophylactiques et diagnostiques utiles. En outre, on peut utiliser ces VLP pour encapsuler des fractions voulues, par exemple, des agents thérapeutiques ou diagnostiques, ou des AND "marqueurs", et les VLP obtenues utilisées comme vecteurs d'administration in vivo ou comme pseudovirions permettant d'évaluer l'efficacité d'un vaccin.
Patent CA-2302677-C (CA)
Inventor: POON KAR-FAT
IPC: H04B17/00
Filed: 1998-09-07
Granted: 2007-11-20
Abstract: The present invention relates to test transmitter for verifying the positioning of antennas in a mobile telecommunications system and a method for manufacturing such a test transmitter that is particularly well suited for indoor use. A mobile terminal is modified so that it can transmit in the downlink frequency band, and preferably so that it can transmit one or more of the signal types used for downlink signalling, used in the mobile telecommunications system.
Patent CA-2309599-C (CA)
Title: Improvements in or relating to displacement assays
Inventor: BERRY MARK JOHN
IPC: G01N33/553
Filed: 1998-11-23
Granted: 2009-03-17
Abstract: Disclosed is a method of detecting the presence of an analyte of interest in the sample, the method comprising the steps of: reversibly immobilising on a first surface a displaceable moiety; exposing the first surface to a sample comprising the analyte of interest, the analyte of interest specifically displacing the displaceable moiety from the first surface; causing the displaceable moiety displaced from the first surface to contact a second surface bearing a capture moiety which specifically binds to the displaceabl e moiety, so as to capture the displaceable moiety on the second surface, said capture generating a detectable signal; and detecting the signal.
Patent CA-2312161-C (CA)
Inventor: KONISHI RYOICHI
IPC: C05F17/02
Filed: 2000-06-22
Granted: 2008-10-07
Abstract: The present invention provides a composting accelerator for a plant-derived material, which accelerator comprises wheat bran and/or low-grade flour powder and an organic waste matter and/or organic fertilizer, and optionally a specific composting assistant; and a compost producing process comprising adding, to a plant-derived material, wheat bran and/or low-grade flour powder and an organic waste matter and/or organic fertilizer and optionally a specific fertilization assistant and carrying out composting.
Patent CA-2313662-C (CA)
Title: Pivotal edge cleaning brushes for vacuum cleaner
Inventor: MCCORMICK MICHAEL J
IPC: A47L9/04
Filed: 2000-07-10
Granted: 2006-05-23
Abstract: A vacuum cleaner includes a housing having a handle pivotally mounted to a nozzle assembly. An agitator is received in an agitator cavity formed in the nozzle assembly. A suction fan and suction fan drive motor are carried on the housing. An edge cleaning brush is pivotally mounted to the nozzle assembly along a lateral edge of the nozzle assembly adjacent the agitator cavity. The brush includes a body having a series of apertures for receiving cleaning bristles and a pair of opposed mounting lugs. The edge cleaning brush is received in a recess with the mounting lugs held in a pair of opposed mounting openings in the nozzle assembly.
Patent CA-2314544-C (CA)
Inventor: BOURDELAIS JEAN-MARC
IPC: H04H20/76
Filed: 2000-07-10
Granted: 2008-03-25
Abstract: Audiovisual reproduction consoles such as jukeboxes (100.1-n) are connected by telephone and modem (30) to a central server (10) which has a database (11) containing operational data and songs and a manager (12) linked to an Internet service provider (14). An operator using a PC (20) is able to make choices through the Internet to control songs played on each jukebox and also to monitor operational data
Patent CA-2328694-C (CA)
Title: Procede psa pour l'elimination de la majeure partie du dioxyde de carbone d'un gaz humide a haute temperature
Inventor: SIRCAR SHIVAJI
IPC: B01D53/047
Filed: 2000-12-15
Granted: 2004-08-10
Abstract: Un procédé et un appareil d'adsorption modulée en pression ou sous vide sont utilisés pour la séparation et la récupération de certains composants gazeux, comme le dioxyde de carbone dans des mélanges de gaz chaud contenant de la vapeur d'eau. Le procédé comprend l'introduction du mélange de gaz d'alimentation à une température élevée dans une extrémité d'alimentation d'une colonne adsorbeuse contenant un adsorbant. L'adsorbant adsorbe de préférence au moins un composant adsorbable. Un effluent adsorbeur, débarrassé du composant adsorbable, est retiré d'une extrémité de produit de la colonne adsorbeuse. La colonne adsorbeuse est dépressurisée sous la pression atmosphérique et puis purgée à la vapeur pour retirer un effluent contenant un mélange avec au moins un composant adsorbable et H2O. Ensuite, la colonne adsorbeuse est mise sous pression en introduisant un gaz débarrassé du composant adsorbable. Les étapes sont répétées de façon cyclique.
Patent CA-2330281-C (CA)
Title: Fibre optique d'amplification optique et procede de fabrication d'un tel fibre
Inventor: ISHIKAWA SHINJI
IPC: C03B37/018
Filed: 2000-02-25
Granted: 2008-09-16
Abstract: La présente invention concerne un fibre optique d'amplification, muni d'une structure permettant des caractéristiques de gain uniforme ou des caractéristiques d'oscillation dans des bandes de longueur d'onde plus larges. Le fibre optique d'amplification est muni d'une deuxième région dopée comprenant une première région dopée incluant un centre d'axe optique et présentant un diamètre supérieure à celui de la première région dopée. Le procédé de fabrication consiste en l'ajout d'au moins un parmi Al2O3, P2O5, Y2O3 et B2O3 dans la deuxième région dopée en tant qu'oxydes d'éléments à valences différentes de celles des cations constituant les principaux matériaux dudit fibre optique. On ajoute, un parmi Er, Nd, Tm, Pr en tant qu'éléments de terre rare en sus desdits oxydes dans la première région dopée.
Patent CA-2330457-C (CA)
Inventor: DIDILLON BLAISE
IPC: C10G29/10
Filed: 2001-01-02
Granted: 2010-03-30
Abstract: Procédé d'élimination de mercure et éventuellement d'arsenic d'une charge hydrocarbonée comprenant : 1) une distillation de la charge hydrocarbonée de façon à obtenir au moins une coupe légère et au moins une coupe lourde. 2) un traitement d'au moins une dite coupe lourde lequel traitement comporte deux étapes : - une première étape de mise en contact de la coupe dite lourde avec de l'hydrogène et un catalyseur. - une deuxième étape consistant à faire passer l'effluent de la première étape sur une masse de captation de mercure, éventuellement d'arsenic.
Patent CA-2330943-C (CA)
Title: Hair treatment compositions
Inventor: ELLIS FRANCES
IPC: A61K8/00
Filed: 1999-05-15
Granted: 2009-12-01
Abstract: The invention provides a hair treatment composition such as a shampoo or conditioner suitable for topical application to hair for the repair and prevention of damage, comprising (i) cholesterol, and (ii) a hair benefit agent which is a mixture of a basic amino acid and a fatty acid. Preferably the cholesterol and hair benefit agent are compounded into a dispersion of multilamellar vesicles, stabilised with nonionic surfactant.
Patent CA-2331514-C (CA)
Title: Radiation protective device
Inventor: FISHMAN STEVEN J
IPC: A61B19/00
Filed: 1999-05-07
Granted: 2008-10-28
Abstract: The present invention is a bioimplantable device for adjusting the position of and/or shielding selected tissues of a human body during radiation therapy. The device includes a selectively inflatable hollow structure formed from a biocompatible material, an inflation port in communication with the hollow structure effective to communicate an inflation material to within the hollow structure and at least one tissue fixation element disposed on the hollow structure. In another embodiment, the device is a multi-layer structure which can be implanted to block radiation and/or displace tissues from the path of the radiation.
Patent CA-2334010-C (CA)
Inventor: BOBROW MARK NORMAN
IPC: C09B11/28
Filed: 1998-06-04
Granted: 2009-09-08
Abstract: L'invention concerne de nouveaux substrats contenant du p-hydroxycinnamyle pouvant être utilisés dans le dépôt catalysé d'enzymes reporteurs pour amplifier le signal détecteur et élargir la plage de détection de dosages. La figure représente la détection d'antigènes précoces de cytomégalovirus au moyen du dépôt catalysé d'enzymes reporteurs pour amplifier le signal détecteur.
Patent CA-2347343-C (CA)
Title: A method for preemptive screen rendering
Inventor: BALLANTYNE IAN
IPC: G06F3/14
Filed: 2000-05-10
Granted: 2007-11-27
Abstract: A method of rendering screen of a computer display device under conditions requiring frequent repainting of the screen is disclosed. The display is a part of a computer system running an application under control of an operating system. The application detects the onset of conditions requiring frequent repainting of the screen by checking messages sent by the operating system to the application's message queue. The application then starts the repainting of the screen based on the information retrieved from the queue while checking periodically the message queue to see if the originally detected conditions still apply. If this is the case, the application terminates the original repainting operation and starts a new repainting operation based on the updated information retrieved from the message queue. This cycle is repeated until it is determined that the originally detected conditions no longer apply, in which case a final complete repaint of the screen takes place. The method is particularly useful for the display of a graphically complex scene during a navigation operation, such as panning or zooming, when complete repainting of the scene as the navigation progresses fails to provide to the user an acceptable visual feedback of the navigation progress.
Patent CA-2348415-C (CA)
Title: Method for gold deposition
Inventor: BRAUN EREZ
IPC: C12Q1/68
Filed: 1999-10-27
Granted: 2010-09-07
Abstract: A method for depositing gold on a substrate is provided. By this aspect, nucleation centers are bound, deposited or formed at one or more sites on the substrate, the substrate is then contacted with a treatment composition which comprises soluble gold-providing agent from which gold is deposited onto a nucleation center to yield gold metal deposits. The method of the invention may be used for a variety of image enhancing techniques as well as diagnostic and analyte detection techniques.
Patent CA-2353162-C (CA)
Inventor: SCHMITT-LEWEN MARTIN
IPC: B41F35/06
Filed: 2001-07-16
Granted: 2009-06-16
Abstract: A method for clearing a re-imageable printing form (36), particularly one from which the ink has been washed, is characterized in that the printing form (36) is treated with a liquid or gaseous clearing solution (42). A device for clearing a re-imageable printing form (36) from which the ink has been washed is characterized by a device (44) for applying liquid or gaseous (42) clearing solution to the printing form (36).
Patent CA-2356930-C (CA)
Inventor: PIETRAS BERND-GEORG
IPC: E21B19/16
Filed: 1999-11-29
Granted: 2007-02-20
Abstract: An apparatus for facilitating the connection of tubulars using a top drive, the apparatus comprising a supporting member (13) connectable to said top drive (3) characterised in that it further comprises an internal tool (30) for engaging said tubular (7) and an external clamping device (39) for engaging said tubular (7).