baber/WOPTO huggingface dataset:
Patent SG-10201806693X-A (SG)
Title: Anti-myostatin antibodies and methods of use
Inventor: RUIKE YOSHINAO
Filed: 2017-06-16
Abstract: ANTI-MYOSTATIN ANTIBODIES AND METHODS OF USE 5 The disclosure provides anti-myostatin antibodies and methods of making and using the same. Nucleic acids encoding the anti-myostatin antibodies and host cells comprising the nucleic acids are also provided. The disclosure also provides polypeptides containing a variant Fc region and methods of making and using the same. Nucleic acids encoding the polypeptides and host cells comprising the nucleic acids are also provided. 10 Figure 1
Patent SG-10201901329S-A (SG)
Title: Method and system for performing a planning process of a railway service
Inventor: NORRIS MARTIN JOHN E
Filed: 2019-02-15
Abstract: METHOD AND SYSTEM FOR PERFORMING A PLANNING PROCESS OF A RAILWAY SERVICE 5 Method for performing a planning process of a railway service comprising the steps of: - acquiring (200), using sensors (300), train data relative to measured movement of trains 10 along a railway track (302), and reference data relative to a reference timetable of trains trips; - generating, with an elaboration unit (308), a reference three dimensional graph (20) including a three dimensional cylinder (21) and associating a reference Cartesian system (XYZ) to the cylinder (21); 15 - calculating, with the elaboration unit (308), coordinates of history points and reference points for each train in the reference Cartesian system (XYZ) as a function respectively of said train and reference data, the coordinates of the history and reference points in a planar direction (XY) of the reference Cartesian system (XYZ) being function of a train position corresponding respectively to said train and reference data, and the coordinates 20 of the history and reference points in a vertical direction perpendicular to the planar direction (XY) being function of a time associated with said train position respectively in the train and reference data, the coordinates of each history and reference points corresponding to a point belonging to the surface of the cylinder (21); - displaying on a display unit (310) the three dimensional graph and the history and 25 reference points; - planning, with a control unit (304), the railway service as a function of the data displayed on the display unit (310). Figure 3 30
Patent SG-10201908467R-A (SG)
Title: Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
Inventor: CORTE JAMES R
Filed: 2015-01-30
Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This 5 invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same. [No Figure]
Patent SG-10201909400R-A (SG)
Title: Device for delivering particles
Inventor: TSUI VICTOR
Filed: 2015-02-26
Abstract: DEVICE FOR DELIVERING PARTICLES A delivery device is disclosed that can have a cylinder holding pressurized gas and a cassette holding particles. When the delivery device is actuated, the delivery device can spread the particles over a large target area, with a reasonably uniform distribution over that target area, and can operate quietly. The particles can be held in a cassette. The cassette can be configured to release or discharge over 70% of the particles during use. The device can have a safety interlock to prevent or minimize the risk that the device will be unintentionally activated. The device can have a silencer. (Figure 1b)
Patent SG-11201407801V-A (SG)
Title: Methods for use of mixed multifunctional surfaces for reducing aggregate content in protein preparations
Inventor: GAGNON PETER
IPC: C07K1/18
Filed: 2013-02-06
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 5 December 2013 (05.12.2013) WIPOIPCT (10) International Publication Number WO 2013/180648 A1 (51) International Patent Classification: C07K1/16 (2006.01) C07K16/00 (2006.01) C07K1/18 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/SG2013/000047 6 February 2013 (06.02.2013) English English (30) Priority Data: 61/653,904 31 May 2012 (31.05.2012) US (71) Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH [SG/SG]; 1 Fusionpolis Way, #20-10 Connexis, Singapore 138632 (SG). (72) Inventor: GAGNON, Peter; 20 Biopolis Way, #06-01 Centres, Singapore 138668 (SG). (74) Agent: SPRUSON & FERGUSON (ASIA) PTE LTD; P. O. Box 1531, Robinson Road Post Office, Singapore 903031 (SG). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: — with international search report (Art. 21(3)) 00 •t o 00 i-H o CJ (54) Title: METHODS FOR USE OF MIXED MULTIFUNCTIONAL SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS (57) Abstract: Methods for reduction of aggregate levels in antibody and other protein preparations comprising the steps of treat­ ment with an organic multivalent cation (e.g., ethacridine, chlorhexidine, or polyethylenimine) and treatment with composition a having combination of a surfaces bearing electronegative chemical moieties and surfaces bearing electropositive chemical moieties.
Patent SG-11201803832Q-A (SG)
Title: Method for manufacturing bone-regeneration material comprising biodegradable fibers by using electrospinning method
Inventor: KASUGA TOSHIHIRO
IPC: D01F6/62
Filed: 2017-04-28
Abstract: METHOD FOR MANUFACTURING BONE-REGENERATION MATERIAL COMPRISING BIODEGRADABLE FIBERS BY USING ELECTROSPINNING METHOD [Document Name] [Abstract] [Problem to be Solved] A new method for producing a bone-regeneration material in which a biodegradable fiber including PLGA contains calcium phosphate particles by electrospinning with commercial effectiveness and a new bone-regeneration material produced by the method is demanded. [Solution] A biodegradable fiber in which the calcium phosphate fine particles are dispersed substantially uniformly in the biodegradable fiber is produced by heating a PLGA resin in a kneader to soften the PLGA resin to a viscosity of 102 to 107 Pa s, mixing powder of calcium phosphate fine particles with the softened PLGA resin by providing the powder to the kneader while rotating the blade of the kneader; rotating the blade of the kneader with continuous force under the heating to knead the mixture so that thermal and mechanical energy is applied to the mixture to crush aggregates of calcium phosphate fine particles, and thereby prepare a composite of the PLGA resin and the calcium phosphate fine particles - 49 - dispersed therein; dissolving the composite with a solvent, and stirring for a predetermined time to prepare a spinning solution in which the PLGA resin is completely dissolved in the solvent and the calcium phosphate fine particles are dispersed without aggregation in the solvent in which the PLGA resin is dissolved; and electrospinning the spinning solution. [Selected Drawing] Figure 4 (1)
Patent SG-11201908205T-A (SG)
Title: Inverting mechanism for a machine for shaping glass items
Inventor: TIJERINA RAMOS VÍCTOR
IPC: C03B9/16
Filed: 2017-08-02
Abstract: INVERTING MECHANISM FOR A MACHINE FOR SHAPING GLASS ITEMS The present invention related to an inverting mechanism of a glass forming 5 machine which comprises: a supporting structure. A shaft horizontally located over the upper portion the supporting structure to rotate on its own axis. Drive means coupled to a shaft to provide rotational movement to the shaft to the left or right. A cylindrical body having a longitudinal opening in an eccentric reference axis, which is securely coupled to the shaft through its longitudinal opening, in an eccentric 10 position. At least one hollow cylinder coupled with each cylindrical body having attached supports to its outer part which are connected to neck ring holder arms so that, by means of a first sliding movement of the hollow cylinder on the cylindrical body, it provides a lateral movement to the right or to the left to open and close the neck ring holder arm supports in parallel and, by means of a rotational movement, it 15 moves the neck ring holder arms with a 180° movement from a parison mold to a finish blow mold. Figure 4
Patent AT-402792-B (AT)
Title: Independently operating breathing aid device
Inventor: REINDL GUENTHER
IPC: A61M21/00
Filed: 1996-03-11
Granted: 1997-08-25
Abstract: A breathing aid device is employed to help a person to achieve and retain slower, rhythmical lower abdomen breathing. This consists optionally of a combination of a mechanical device acting on the back of the prostrate person with short verbal statements reproduced to correlate with the breathing phases, extended in variants by the likewise breathing-phase correlated reproduction of images and films, for example with the aid of a multimedia computer. Optional provision of accompanying music and relaxing sounds. The advance consists in the provision of short naturally spoken texts, images or films reproduced in time- association with the breathing phases. After the recording of the time behaviour of an application of this breathing aid appliance on a user, the breathing aid can be provided - with the mechanical device switched off - by verbal statements alone, extended in variants to include films.
Patent AT-405040-B (AT)
IPC: B41F15/40
Filed: 1995-05-18
Granted: 1999-04-26
Abstract: Three hollow moulding beam (2) has the surface shell of its hollow profile (21) designed as a bonding surface over at least part of the total circumference of the moulding. In the longitudinal direction, it virtually covers the application width. The hollow profile is bonded to at least one other second profile (22-24,221,226), which has at least one surface complementary to the binding surface of the hollow profile. The planes are parallel and roughly equal in area, forming a one-piece construction of the beam.
Patent AT-409354-B (AT)
Title: Milling tool
Inventor: KIRCHBERGER PETER DIPL ING
IPC: B23C5/20
Filed: 1998-05-19
Granted: 2002-07-25
Abstract: The invention relates to a milling tool having a considerable longitudinal extent for the efficient machining of those surfaces of rotatable workpieces which are normal to or at an angle to the axis. Proposed according to the invention for this purpose is a tool 1 in which the number of the circumerentially arranged cutting elements 14 and/or their cutting-edge length varies over the longitudinal extent of the working surface 13. <IMAGE>
Patent DK-152231-B (DK)
Inventor: HANSEN GUNVER
IPC: F21S13/00
Filed: 1985-01-17
Abstract: A light fixture (1), preferably for candlelights (4), comprises a plurality of arms (2) interconnected about a vertical symmetrical axis (3) and preferably made of metal wire. The arms (2) are pivotably interconnected about the vertical symmetrical axis by means of a separate, rigid, and preferably elongated holder (5). Thus the arms (2) can be locked in predetermined angular positions by means of at least one loose annular locking means (6, 7) when the candelabrum (1) is used, whereas said arms (2) can turn freely about the symmetrical axis (3) and thereby be folded towards one another in such a manner that the light fixture (1) is flattened when the locking means (6, 7) are removed. In this manner a simple light fixture (1) is provided, the arms of which can be turned in a simple manner about a symmetrical axis after removal of one or more locking means and thereby be folded towards one another in such a manner that the light fixture in an advantageous manner only takes up little room when put away or transported.
Patent HU-201191-B (HU)
Inventor: SZABADOS MIKLOS
IPC: H04L25/38
Filed: 1988-01-20
Abstract: A találmány tárgya kapcsolási elrendezés mintavevő jel előállítására aszinkron soros adatátvitelhez az adatok csomagonkénti továbbításának esetére, amelyben fázisválasztó áramkör, pillanatérték tároló, a mintavételezés gyakoriságát meghatározó órajel frekvenciáját leosztó frekvenciaosztó áramkör és ezen frekvenciaosztó áramkört alaphelyzetbe állító impulzuselőállító áramkör van. A találmány lényege az, hogy a mintavételezés gyakoriságát meghatározó órajel (A) bemenet egyaránt rá van kapcsolva a fázisválasztó áramkör (1) egyik bemenetére és a pillanatérték tároló (2) egyik bemenetére, a vett adatjel (B) bemenet pedig rá van kapcsolva az impulzuselőállító áramkör (3) bemenetére, továbbá az impulzuselőállító áramkör (3) kimenete csatlakozik a pillanatérték tároló (2) másik bemenetéhez és a frekvenciaosztó áramkör (4) egyik bemenetéhez, a pillanatérték tároló (2) kimenete csatlakozik a fázisválasztó áramkör (1) másik bemenetéhez, a fázisválasztó áramkör (1) kimenete pedig a frekvenciaosztó áramkör (4) másik bemenetéhez csatlakozik, és ezen frekvenciaosztó áramkör (4) kimenete csatlakozik a mintavevő (C) jelkimenetre, (1, ábra)  0> A leírás terjedelme: 4 oldal, 1 ábra -1-
Patent HU-197706-B (HU)
Inventor: NEMETH GYULA
IPC: B65D47/20
Filed: 1987-01-26
Abstract: A találmány italkeverő- és adagolóberendezés, amelynek keverőedénnyel kapcsolatban álló sűrítménytartálya és a keverőedénybe torkolló vízbevezető csöve van. A találmány lényege, hogy a vízbevezető cső (2) a keverőedénybe (1) egy abba koncentrikusan be- nyúló injektorcsővel (3) torkollik, és a sürítménytartály (4) a keverőedény (1) palástján az injektorcső (3) tartományában kiképzett furathoz csatlakoz k ejtővezeték (5) révén (1. ábra)  ZafytL·   I .. .     LJ     j  I   -1-
Patent SE-334617-B (SE)
Inventor: FISCHER A
IPC: C07D403/04
Filed: 1965-01-20
Abstract: The invention relates to an amide or salt thereof or an imide of a dicarboxylic acid, e.g. oxalic, succinic, maleic, dichloromaleic or phthalic and a compound of the general formula <FORM:1086614/C2/1> where R1 is a phenyl or cyclohexyl radical and R2 is chlorine or bromine.  In an example reaction of 1-phenyl-4-amino-5-hydroxypyridazone-(6) with dichloromaleic acid gives the dichloromaleimide of 1-phenyl-4-amino-5-hydroxypyridazone-(6) which is reacted with phosphorus and hydrochloride, thionyl chloride or phosgene to produce 1-phenyl-6-dichloromaleimido-5-chloropyridazone which on hydrolysis yields 1-phenyl-4-dichloromaleamido-5-chloropyridazone-(6). In another example by reacting 1 - phenyl - 4 - amino - 5 - chloropyridazone with oxalylchloride there is produced N - [4 - (1 - phenol - 5 - chloropyridazone - 6)-yl]-ozamic acid.ALSO:Plant growth regulants contain as active ingredients an amide or salt thereof or an imide of a dicarboxylic acid and 1-phenyl-4-amino-5-chloropyridazone-(6); 1-phenyl-4-amino-5-bromopyridazone - (6), 1-cyclohexyl-4-amino-5-chloropyridazone-(6) or 1-cyclohexyl-4-amino-5-bromopyridazone-(6) and a solid or liquid carrier material.  Specified active ingredients are 1-phenyl-4-amino-5-chloropyridazone-(6)-oxalamide, 1-phenyl-4-amino-5-chloropyridazone-(6) -oxalamide sodium salt.
Patent YU-49359-B (YU)
Inventor: BRAEUNLICH GABRIELE
IPC: C07D405/12
Filed: 1996-03-05
Abstract: N-(3-benzofuranil)urea derivati opste formule (I) u kojoj A i D su isti iil razliciti i predstavljaju vodonik, prav ili razgranat acil ili alkoksikarbonil, od kojih svaki ima do 6 ugljenikovih atoma, ili prav ili razgranat alkil koji ima do 6 ugljenikovih atoma, koji moze biti supstituisan karboksilom ili alkoksikarbonilom koji ima do 6 ugljenikovih atoma, fenoksi ili benzoil, ili predstavljaju halogen, karboksil, cijano, nitro, trifluorometil, trifluorometoksi, ili grupu formule -OR5, -S(O)a R6, -(O-CH2-CO)b-NR7R8, -CO-NR9R10, -SO2-NR11R12 ili -NH-SO2R13, u kojima R5, R6, R8, R9, R10, R11 i R12 su isti ili razliciti i oznacavaju vodonik, cikloalkil koji ima 3 do 6 ugljenikovih atoma, benzil ili 5- do 7- clani zasicen ili nezasicen heterociklicni prsten koji ima do 3 heteroatoma iz niza koji cine N, S i O i kojem moze da se pripoji fenilni prsten i koji moze biti supstituisan istim ili razlicitim supstituentima iz niza koji cine halogen, cijano, nitro, ili prav ili razgranat alkil koji ima do 6 ugljenikovih atoma, ili oznacavaju prav ili razgranat alkil, alkenil, ili acil od kojih svaki ima do 8 ugljenikovih atoma, ili oznacavaju fenil, koji moze biti mono- ili di-supstituisan istim ili razlicitim supstituentima iz niza koji cine nitro, halogen, karboksi ili prav ili razgranat alkoksikarbonil koji ima do 6 ugljenikovih atoma, ili R5 oznacava hidroksilnu zastitnu grupu ili prav ili razgranat alkoksikarbonil koji ima do 6 ugljenikovih atoma, ili oznacava prav ili razgranat alkil koji ima do 8 ugljenikovih atoma, koji je supstituisan sa karboksilom, hidroksilom, sa pravim ili razgranatim acilom ili alkoksikarbonilom, od kojih svaki ima do 6 ugljenikovih atoma, fenoksil, benzoil ili 5- ili 7-clani nezasiceni heteroprsten koji ima do 3 hetero atoma iz niza koji cine N, S i/ili O, koji moze biti supstituisan sa halogenom, cijanom, nitro ili sa pravim ili razgranatim alkilom koji ima do 6 ugljenikovih atoma ili R5oznacava grupu formule SO2R14, u kojoj R14 oznacava fenil, trifluorometil ili prav ili razgranat alkil koji ima do 4 ugljenikova atoma, a oznacava broj 0, 1 ili 2, b oznacava broj 0 ili 1, R7 oznacava vodonik ili pravi ili razgranat alkil koji ima do 4 ugljenikova atoma, R13 oznacava aril, koji ima 6 do 10 ugljenikovih atoma, trifluorometil ili prav ili razgranat alkil koji ima do 6 ugljenikovih atoma, R1 predstavlja vodonik, prav ili razgranat alkil koji ima do 6 ugljenikovih atoma, zastitnu amino grupu ili grupu formule -CO-R15, u kojoj R15 oznacava hidroksil, prav ili razgranat alkoksikarbonil koji ima do 6 ugljenikovih atoma, cikloalkil koji ima od 3 do 6 ugljenikovih atoma, piridil, pirolidinil ili prav ili razgranat alkil koji ima do 8 ugljenikovih atoma, koji moze biti supstituisan halogenom, karboksilom ili sa pravim ili razgranatim alkoksikarbonilom koji ima do 6 ugljenikovih atoma, ili oznacava fenil, koji moze biti supstituisan sa hidroksilom, karboksilom ili sa pravim ili razgranatim alkoksi ili alkoksikarbonilom od kojih svaki ima
Patent YU-48537-B (YU)
Inventor: INZ KOTORAS PEPI DIPL
Filed: 1993-02-26
Abstract: Umivaonik sa tuš kadom je opremljen, od ranije poznatim podnim sifonom (G), zavesom (D) sa štipaljkama (J) i klizačem (I), tuš baterijom (F) i kadicom (C), ali se sastoji i od mehaničkog sklopa od sanitarne plastike sa čeličnim ojačanjima za čije potpuno razumevanje treba pročitati opis pronalaska, a sklop je naznačen time, što kada (A), dok leži na podu, svojim otvorom (A4) naleže na podni sifon (G) pri čemu odignuti rubovi kade sprečavaju bočno oticanje vode, a rub prema dovratniku (B) dozvoljava samo rotaciju kade (A) oko dovratnika (B), pa ako se kada rotira do vertikalnog položaja automatski se formira vertikalna obrtna osovina jer se izvrši međusobno uklapanje čelikom ojačanih delova i to redom (A1) i (B1), (A2) i (B2), (A3) i (E1), a važno je napomenuti da je dovratnik (B) zalepljen za pod, dok je umivaonik (E) konzolno vijcima pričvršćen na zid i klasično vezan za kanalizacionu mrežu, a kao što i kada (A) poseduje utore (A5) za vešanje ploče (H), tako i umivaonik (E) poseduje utore za istu namenu, pa se ploča (H) preko čeličnih držača (H1) može zakačiti za oba navedena elementa, a važno je uočiti da se svi metalni delovi konstrukcije izvode od nerđajućeg čelika, s tim da su delovi (A2) i (A3) aksialno pomične osovine (trnovi sa čeličnim oprugama), dok je deo (E1) običan čelični prsten za razliku od delova (A1), (B1) i (B2) koji su oblika polulopti, pa svi metalni delovi zajedno, nazvani metalna ojačanja, omogućuju rotaciju kade (A) oko horizontalne i oko vertikalne ose.
Patent YU-45315-B (YU)
Title: Drum for sprinkling thick solutions of highly abrasive material
Inventor: SVARRER L
IPC: B05B3/10
Filed: 1986-04-09
Abstract: The atomizer wheel is provided along the circumference of its external wall (3) with a number of ejection apertures, in which wear-resistant ceramic linings (7) are arranged by means of replaceable steel bushings (8). The steel bushings (8) and/or the linings (7) project somewhat into the annular chamber of the atomizer wheel and the bushings are sealed against the external wall (3) with sealing rings (11). Moreover, each bushing (8) is provided in its inner surface facing the associate lining (7) with a flat recess (13) extending on either side of the inner surface of the external wall (3). Thereby, the steel bushings (8) may be resiliently deformed without transferring excessive stresses to the linings (7).
Patent ZA-83606-B (ZA)
Title: Expandable van top tent assembly
Inventor: LANGE JACK
IPC: B60P3/34
Filed: 1983-01-28
Abstract: The top of the van includes a perimetrical wall defining an opening (20) with a hinged cover panel (16) which opens to a horizontal position on one side of the van. A tent or enclosure (26) is secured by the edges, around the perimetrical wall of the opening and around the free edges of the cover panel. A plurality of hoop braces (34, 35, 35A) are hinged to the wall and to the cover panel and the flexible enclosure is secured to these hoops so that the hoops are erected when the cover panel is opened. The cover panel is supported horizontally in the opened position by means of tension cables (45) extending from the other edge of the opening, to the hoop braces to thwich it is secured, and is then secured to the distal edge (18) of the cover panel by the other end thereof thus eliminating any need for vertical supports. If desired, a flexible porch (57) can be detachably secured around the three edges of the cover panel when open, and can depend therefrom to the ground. Access to the upper tent portion is from the interior of the van through the opening in the roof thereof uncovered when the cover panel is open.
Patent ZA-87552-B (ZA)
Title: New dihydrobenzofuran-and chroman-carboxamide derivatives,processes for the preparation thereof and use thereof as neuroleptics
Inventor: FRANCESCHINI JACQUELINE
IPC: C07D/
Filed: 1987-01-26
Abstract: The invention relates to new dihydrobenzofuran- and chroman-carboxamide derivatives of the general formula:   <IMAGE> (I) in which R and R' are each hydrogen or methyl; n is 1 or 2; m is 1 or 2; Z is either   <IMAGE> (a)   wherein R1 and R2 are lower alkyl, or <IMAGE> (b)  wherein R3 is alkyl, alkenyl, cycloalkyl-alkyl, cycloalkenyl-alkyl, X is H, NH2, methoxy, or methyl and Y is H, Cl, cycloalkylmethylsulfonyl, alkylsulfamoyl or alkylsulfonyl and to their pharmacologically acceptable acid addition salts and their optical isomers, to the processes for the preparation thereof and to the use thereof as medicaments, especially as neuroleptics.