baber/WOPTO huggingface dataset:
Patent DK-0721510-T3 (DK)
Inventor: ACRES BRUCE
IPC: A61K35/76
Filed: 1994-09-28
Granted: 2003-11-17
Abstract: Use of a viral vector contg. in its genome a DNA fragment (I) contg. ≥ 1 gene encoding all or part of an agent (A) that modulates the immune and/or inflammatory response for the treatment of cancer in mammals is new. (A) can be a cell surface co-stimulatory molecule, a chemokine, a monoclonal antibody against a lymphocyte surface maker, a super antigen characteristic of an infectious organism (bacterium, virus or parasite), a polypeptide with adjuvant activity or esp. a cytokine. Also claimed is the use of a viral vector with positive tropism for cancer cells contg. in its genome a DNA fragment including ≥ 1 gene, encoding an agent able to destroy cancer cells, under control of appropriate expression elements, for selective delivery of the agent to cancerous tumours.
Patent DK-0672374-T3 (DK)
Inventor: MASSEY RAYMOND DENNIS
IPC: A47J31/56
Filed: 1995-03-14
Granted: 1998-09-21
Abstract: A continuous boiling water unit is disclosed and comprises a water heating tank (1) containing an electric heating element (2) near the bottom of the tank (1) and a level control tank (3) mounted alongside the heating tank (1). An interconnecting steam communication port (21) is located between the level control tank (3) and the heating tank (1), together with a draw-off connection (23) and a flow connection (10). There further comprises an electronic temperature sensor in the form of a thermister (50) operable to sense the temperature of water in the heating tank (1), and upon sensing boiling of the water in the heating tank (1), operable to cause cut-off of the supply to the heating element (2). <IMAGE>
Patent DK-0714645-T3 (DK)
Inventor: GABRIEL STEFAN M
IPC: A61F2/38
Filed: 1995-11-30
Granted: 2000-07-31
Abstract: A modular knee prosthesis includes a femoral component having a pair of spaced apart condylar portions each having a superior articulating surface and an inferior surface, and a boss structure disposed between and connecting the condylar portions. The prosthesis further includes an elongate stem member that mounts within the medullary canal of a distal portion of a femur, a collar and at least one securing bolt. The collar mounts upon the external end of the stem member, and has a distal surface that is substantially transverse to a longitudinal axis of the stem member when mounted thereon. The collar distal surface and the inferior surface of the boss structure define a selected mounting angle therebetween, and the securing bolt, which is adapted to mount within an aperture formed in the boss structure, has a head portion with a spherical first surface from which an elongate shaft portion extends. The shaft of the securing bolt can be disposed at a generally centrally located position or at a non-centrally located position on the head portion of the bolt. <IMAGE>
Patent DK-0697248-T3 (DK)
Inventor: CHAMPSEIX HENRI
IPC: B01L3/00
Filed: 1995-08-16
Granted: 2001-01-22
Abstract: Reactant distributor comprises a number of airless supple pockets and is dimensioned to fit on the side of the device, ensuring the connection of the pockets by opening their valves. The distributor (1) also contains several retractable pockets (14) full of reactant, arranged near the base. The valves (13) open at the bottom of the distributor, while at least one retractable pocket (15) intended for waste is placed near the top of the distributor. The distributor is mounted on a horizontal support plate which slides along the side of the device. Opening mechanisms for the valves (13) cross openings in this plate.
Patent DK-0741785-T3 (DK)
Inventor: GOLDSTEIN STEVEN A
IPC: C12N15/87
Filed: 1995-02-21
Granted: 2000-04-10
Abstract: Disclosed are methods, compositions, kits and devices for use in transferring nucleic acids into bone cells in situ and/or for stimulating bone progenitor cells. Type II collagen and, particularly, osteotropic genes, are shown to stimulate bone progenitor cells and to promote bone growth, repair and regeneration in vivo. Gene transfer protocols are disclosed for use in transferring various nucleic acid materials into bone, as may be used in treating various bone-related diseases and defects including fractures, osteoporosis, osteogenesis imperfecta and in connection with bone implants.
Patent DK-0757796-T3 (DK)
Inventor: SCHUSTER MARTIN
IPC: G01R15/16
Filed: 1995-04-19
Granted: 1999-03-22
Abstract: A device for connecting a voltage display apparatus to a sensor which is capacitively coupled to a conductor of a high-voltage power supply system comprises a circuit (2) which has an input for the electrical voltage delivered by the sensor and an output for connecting the voltage display apparatus. The circuit (2) is accommodated in a closed housing (1) of a preassembled module. Emerging from the housing (1) is a coaxial cable (5) which is connected at one end to the input of the circuit (2) and which is provided at its other end with a connector plug (8). An earthing connection (6) is connected to a ground point of the circuit (2). At least one socket-contact pair (3, 4), forming the output of the circuit (2), is used to produce a plug connection with the voltage display apparatus.
Patent DK-0768941-T3 (DK)
Inventor: KRENCHEL HERBERT
IPC: B28B3/20
Filed: 1995-07-07
Granted: 2000-06-26
Abstract: Shaped bodies of particulate material are produced by introducing an easily flowable slurry of water and particulate material into a mold with perforated walls and applying a sufficiently high pressure to the slurry in the mold so as to express a sufficient proportion of the liquid to allow physical contact and interengagement between the particles. The extrusion is carried out continuously in an extension process including: (A) introducing the slurry under high pressure, (B) conveying the slurry through a shaping section to (C) a draining and consolidation section with drain holds or slits ( 3 ), to leave the extruder through (E) an exit section in the form of a solid body ( 4 ).
Patent DK-0785781-T3 (DK)
Inventor: WYTHES MARTIN JAMES
IPC: A61P17/02
Filed: 1995-10-05
Granted: 2002-03-18
Abstract: The invention provides the use of a compound formula (I) wherein R1 and R2 independently represent H or C1-C6 alkyl, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment of: dermatological disorders; peripheral neuropathies; arthritis; gastrointestinal or urogenital disease; headache associated with substances or their withdrawal; tension headache; pediatric migraine; post-traumatic dysautonomic cephalgia; orofacial pain; allergic or chronic obstructive airways diseases, glaucoma or ocular inflammation; or prophylaxis of migraine
Patent DK-0752396-T3 (DK)
Inventor: BASTIAN WOLFGANG
IPC: C04B28/34
Filed: 1996-07-04
Granted: 2003-02-24
Abstract: The inorganic foam material consists of (by wt.): (a) 40-90 pts. of a soln. contg. 20-70% Al(H2PO4)3 and 30-80% water; (b) 5-55 pts. of a mixt. contg. 10-70% MgO, 10-70% mica, 10-70% Al(OH)3 and 2-20% MnO2; and (c) 1-30 pts. of a foam former contg. 3-33% H2O2 and 67-97% water. Also claimed is a process for the prodn. of the above inorganic foam material.
Patent DK-0941315-T3 (DK)
Inventor: MIZZEN LEE
IPC: A61K39/04
Filed: 1997-11-25
Granted: 2006-05-15
Abstract: The present invention relates to a vaccine for inducing an immune response to an antigen in a vertebrate (e.g., mammal) comprising an antigen and all or a portion of a stress protein or all or a portion of a protein having an amino acid sequence sufficiently homologous to the amino acid sequence of the stress protein to induce the immune response against the antigen. In a particular embodiment, the present invention relates to vaccines and compositions which induce a CTL response in a mammal comprising an antigen and all or a portion of a stress protein. In another embodiment, the invention relates to vaccines and compositions which induce an immune response to an influenza virus in a mammal comprising an antigen of the influenza virus and all or a portion of one or more stress proteins. The invention also relates to vaccines and compositions for inducing a CTL response to a tumor-associated antigen comprising a tumor-associated antigen and all or a portion of the stress protein. The invention also relates to vaccines and composition for suppressing allergic immune responses to allergens comprising an allergen and all or a portion of a stress protein.
Patent DK-1023051-T3 (DK)
Inventor: STARK PAUL
IPC: A61K47/12
Filed: 1997-12-05
Granted: 2003-09-01
Abstract: An oral morphine multiparticulate formulation for once-daily administration to a patient, comprising sustained release particles each having a core containing water soluble morphine and an osmotic agent, the core being coated with a rate-controlling polymer coat comprised of ammonio methacrylate copolymers in an amount sufficient to achieve therapeutically effective plasma levels of morphine over at least 24 hours in the patient.
Patent DK-0952619-T3 (DK)
Inventor: KESPER HEINRICH
IPC: H01M10/52
Filed: 1998-04-20
Granted: 2004-08-09
Abstract: A catalytic hydrogen/oxygen recombination unit (1) for batteries has a space (6) connected to the battery connection channel by an opening and to the atmosphere by an ignition suppressing element.
Patent DK-0971710-T3 (DK)
Inventor: WEICHSELBAUM RALPH R
IPC: A61K31/4741
Filed: 1998-03-25
Granted: 2004-09-27
Abstract: Combination of low doses of irradiation and chelerythrine results in increased apoptosis in tumor cells. The doses of either irradiation or chelerythrine alone are such that increased apoptosis or decreased tumor growth or proliferation would not be expected.
Patent DK-1016473-T3 (DK)
Inventor: BUERGEL LONKA
IPC: B21D22/12
Filed: 1999-12-15
Granted: 2004-08-02
Abstract: To give a rounded profile to edges and corners of shaped workpieces, with small radii, the shaping action is wholly through the use of high pressure fluids at the edge/corner zones. The shaping mold gives expansion zones (8) at the edge/corner areas (7) of the workpiece, where the workpiece is fitted into a shaped recess together with an insert (6) to expand the corner/edge zones into the expansion spaces by expanding units (9) of tough and flexible polymer or metal materials.
Patent DK-1071805-T3 (DK)
Inventor: HAWKINS LYNDA K
IPC: C12N15/09
Filed: 1999-04-19
Granted: 2011-09-26
Abstract: Adenoviral vectors, including mutant adenoviruses, that have restriction sites in the E3 region, that facilitate its partial or total deletion, or select genes contained therein, and compositions and methods for substituting heterologous gene(s), if desired, which gene(s) will exhibit an expression pattern, both in terms of timing and degree of expression, similar to the endogenous adenoviral gene that it replaces, and further optionally including mutations in other parts of the adenoviral genome, including certain E1B or E1A regions, and that have applications for diagnosing or treating disease, preferably disease involving unwanted cell growth, including cancer.
Patent ES-2226736-T3 (ES)
Inventor: DEVALLEZ ALAIN
IPC: B61F1/10
Filed: 2000-05-12
Granted: 2005-04-01
Abstract: The bodywork for a railway wagon has a chassis with a bogie and suspension and couplings. The bogie has a load traverse on w a part (A) of the chassis is in contact., the secondary suspension and the linkages. The chassis part has a welded structure wit sections (1,2,7,8) assembled without the load traverse.
Patent ES-2220452-T3 (ES)
Inventor: GUTMAN ARIE
IPC: C08G18/32
Filed: 2000-04-23
Granted: 2004-12-16
Abstract: The invention relates to polyaldimines of formula [1] and their use within moisture curable one part polyurea compositions.wherein j is an integer of 3 to 30 and R2 is unsubstituted homocyclic or heterocyclic aryl radical or alkyl, alkoxy, alkylthio or halogen substituted homocyclic or heterocyclic aryl radical.
Patent ES-2207497-T3 (ES)
Inventor: DOYLE KEVIN J
IPC: A61P9/14
Filed: 2000-03-28
Granted: 2004-06-01
Abstract: This invention relates to compounds formula (I) and pharmaceutically acceptable salts thereof which are inhibitors of protein kinase activity, to pharmaceutical compositions containing these pyrazoles and to processes for preparing these pyrazoles.
Patent ES-2216888-T3 (ES)
Inventor: KURRIS JOHANNUS WILHELMUS PASC
IPC: F16L11/12
Filed: 2000-05-10
Granted: 2004-11-01
Abstract: The plastic pipe (1) comprises liquid tight and/or gas tight inner plastic layer (2) provided with an outer plastic layer (3). The outer plastic layer can be deformed plastically under influence of local load.  The hardness of outer plastic layer is lower than that of inner plastic layer. Plastic deformation of outer plastic layer takes place under load which is lower than that which leads to plastic deformation of inner plastic layer. The foaming level of outer layer is 15-85% preferably 20-50%. At least one of plastic layer comprises PVC or ABS. The outer plastic layer is permeable to gas and/or liquid.
Patent ES-2218174-T3 (ES)
Title: Procedimiento de tratamiento del cabello que usa compuestos amino organicos.
Inventor: ELLIS FRANCES ANN
IPC: A61K8/42
Filed: 2000-06-22
Granted: 2004-11-16
Abstract: Un procedimiento para reducir la pérdida de la cutícula de la fibra del cabello de cabello tratado con una composición oxidante, como un decolorante de cabello, comprendiendo el procedimiento la etapa de poner en contacto el cabello, o bien antes o después del tratamiento del cabello con la composición oxidante, con una composición protectora de cutícula que comprende un compuesto amino orgánico seleccionado de: (i) aminoácidos básicos; (ii) urea; (iii) guanidina; (iv) sales y/o derivados de cualquiera de (i) a (iii); (v) mezclas de cualquiera de (i) a (iv).
Patent ES-2232476-T3 (ES)
Inventor: SAUERLAND MANFRED
IPC: E05C9/02
Filed: 2000-07-24
Granted: 2005-06-01
Abstract: The invention relates to a bar lock for locking preferably the doors of a switch cupboard or similar doors or shutters. Said bar lock comprises a base plate or escutcheon mounted on the exterior of the door leaf or the shutter. The system is further provided with an actuator that extends through the door leaf or the shutter in a section and that actuates at least one stay bar that can be displaced in the longitudinal direction along the inner side of the door leaf or shutter.
Patent ES-2338749-T3 (ES)
Inventor: ALVAREZ-BARON STOOF SANTIAGO
IPC: H04W4/14
Filed: 2000-09-22
Granted: 2010-05-12
Abstract: The present invention consists of an electronic device which allows remote management of printers, copiers and/or fax machines (henceforth remote units), that is, without requiring connection to a computer. It consists of three main modules: an SMS terminal; a controlling card; and the case. The controlling card consists of a digital system comprising a central processing unit such as a microcontroller, and a set of peripheral integrated circuits which define the following functions for the system:     1) the series connection of the SMS terminal, such as by a UART 2) connection to the remote unit by a port extension chip, such as integrated 8255.   3) Storage of the program and data in a local memory. 4) Management of the error protection and power system.
Patent ES-2215733-T3 (ES)
Inventor: ALBERG RANDALL L
IPC: A61F13/49
Filed: 2000-09-28
Granted: 2004-10-16
Abstract: A mechanical fastener tape tab laminate comprising a tape tab backing having at least a first distal end portion, an inner tab portion and second distal end portion, the second distal end portion provided with a mechanical fastener material, the first distal end portion provided with an adhesive layer for attachment to a disposable absorbent article, the tape tab backing further having a folded tape portion comprising a backing having an adhesive layer on an outer face and having at least an inner leg portion and an outer leg portion, the outer leg portion having an exposed adhesive provided for attachment to the disposable absorbent article, the inner and outer leg portions separated by at least one fold, the folded tape portion backing having a line of weakness along the at least one fold, wherein the line of weakness is provided on a portion of the tape tab backing spaced from the first distal end portion.
Patent ES-2367475-T3 (ES)
Inventor: MARSHALL CHRISTOPHER
IPC: C07K16/00
Filed: 2000-10-16
Granted: 2011-11-03
Abstract: Isolated polypeptides or polypeptide chains are modified by di-tyrosine cross-linking such that they retain at least one functional activity. In one embodiment, the isolated polypeptide or polypeptide chains comprise at least one di-tyrosine cross-link, wherein at least one tyrosine of the di-tyrosine cross-link originates from a point mutation to tyrosine, and wherein the di-tyrosine cross-linked protein retains at least one function displayed by the protein in the absence of di-tyrosine cross-linking. In another embodiment, the di-tyrosine cross-linked polypeptide or polypeptide chain has enhanced stability compared to the same polypeptide or polypeptide chain in the absence of di-tyrosine cross-linking. A method for stabilization of a polypeptide or polypeptide complex, by the introduction of intra-polypeptide and/or inter-polypeptide di-tyrosine bonds, which simultaneously maintains the structure and function of the polypeptide or polypeptide complex is also described.
Patent ES-2223613-T3 (ES)
Inventor: KOLTERMANN ANDRE
IPC: C12N15/10
Filed: 2000-11-08
Granted: 2005-03-01
Abstract: A method for the production of biopolymers with modified properties wherein at least one cycle comprising the following steps is completed:(a) providing a population of single-stranded polynucleotide molecules, wherein individual polynucleotide molecules comprise homologous and heterologous sequence segments and wherein individual ones of said single-stranded polynucleotide molecules can form double-stranded polynucleotide molecules with other ones of said single-stranded polynucleotide molecules within said population;(b) forming double-stranded polynucleotide molecules from the population of single-stranded polynucleotide molecules provided according to step (a) comprising double-stranded polynucleotide molecules with different heterologous sequence segments;(c) partially and exonucleolytically degrading the single-strands of the double-stranded polynucleotide molecules produced according to step (b); and(d) temple-directed single-stand synthesizing the degraded ends of the partially degraded double strand produced according to step (c),wherein steps (c) and (d) may be carried out sequentially or contemporaneously.
Patent ES-2192185-T3 (ES)
Inventor: HAAKE ANDRE
IPC: E05F15/44
Filed: 2001-01-25
Granted: 2003-10-01
Abstract: The safety switch rail has a number of contact elements (1,2), each incorporating a number of contact lines (5,6), positioned one after the other along a deformable hose (3), with the contact points between their corresponding contact lines separated upon deformation of the hose. The contact lines may be positioned eccentrically relative to each contact element, with an expander wire (9) fitting through the center of each contact line.
Patent ES-2237508-T3 (ES)
Inventor: FIDKOWSKI ZBIGNIEW TADEUSZ
IPC: F25J3/02
Filed: 2001-05-03
Granted: 2005-08-01
Abstract: The process recovers NF3 from a multicomponent fluid containing NF3, one or more components less volatile than NF3, and one or more components more volatile than NF3. The process uses a first distillation column and a second distillation column, each distillation column having a top and a bottom. The process includes the following steps: feeding the multicomponent fluid to the first distillation column at a first feed location below the top of the first distillation column; feeding a cryogenic liquid to the first or second distillation column adjacent the top of the first or second distillation column; withdrawing a mixture containing NF3 from the first distillation column; feeding the mixture to the second distillation column at a second feed location; separating NF3 from the mixture in the second distillation column; and removing a stream of NF3 from the second distillation column.
Patent ES-2220652-T3 (ES)
Title: Procedimiento para la fabricacion de una carcasa tubular de entrehierro.
Inventor: MATERNE THOMAS
IPC: B29C63/38
Filed: 2001-12-15
Granted: 2004-12-16
Abstract: Procedimiento para la fabricación de una carcasa tubular de entrehierro de plástico para bombas con carcasa tubular de entrehierro, especialmente para bombas de calefacción o de agua de refrigeración, preferentemente en el sector del automóvil, caracterizado porque a) un tubo de pared delgada hecho de un plástico se tensa en un mandril con capacidad de abrirse, b) el tubo se recubre o se envuelve con una capa que le proporciona rigidez, c) antes del recubrimiento, o bien durante o después de envolver el tubo, se aplica una resina sintética líquida encima del tubo para crear una unión entre el tubo y la capa que le proporciona rigidez, d) a continuación se endurece el conjunto tensado en el mandril, durante un tiempo predeterminado, a un programa de temperaturas predeterminado, donde el programa de temperaturas se elige de modo que el material termoplástico del tubo extrudido forme una estructura cristalina durante un paso de recocido, e) el mandril se quita del tubo después del tratamientoa temperatura.
Patent ES-2252168-T3 (ES)
Title: Generador de gotas de tinta e impresora equipada.
Inventor: DUNAND ALAIN
IPC: B41J2/025
Filed: 2001-04-10
Granted: 2006-05-16
Abstract: Generador (33) de gotas de tinta para una impresora de inyección de tinta en la que se fracciona un choro de tinta en gotas, comprendiendo específicamente el generador: - un cuerpo (133) del generador, - al menos un generador (14) de ondas acústicas en forma de un cuerpo alargado en una dirección axial a los chorros de tinta, teniendo cada generador (14) una superficie (16) vibratoria perpendicular a la dirección axial de los chorros, alojándose al menos una parte que comprende la superficie (16) vibratoria de cada generador (14) en un alojamiento (13) del cuerpo (133) del generador (33) de gotas, - al menos una cavidad (6) resonante destinada a contener tinta, estando formada cada cavidad (6) eventualmente por una primera parte únicamente en una parte (1) principal de dicho cuerpo (133) del generador (33) y en este caso por una segunda parte en una prolongación (2) de dicho cuerpo del generador enlazada de manera estanca al cuerpo (1) principal del generador, teniendo cada cavidad una llegada (11) de tinta, estando cada cavidad delimitada específicamente por una placa (39) de toberas (36) y por una pared lateral secante a la placa de toberas, definiendo la intersección de la pared (7-10) lateral y de la placa (39) de toberas una primera línea plana de contorno de la pared lateral, incluyendo la placa de toberas una pluralidad de toberas (36) alineadas según una dirección axial de las toberas perpendicular a la dirección axial de los chorros, definiendo la dirección axial de los chorros y la línea axial de las toberas un plano de los chorros, - generador (33) caracterizado porque la pared (7-10) lateral de cada cavidad (6) resonante es secante a la placa (39) de toberas perpendicularmente a ésta a lo largo de toda la primera línea de contorno de esta pared, estando formada la primera línea de contorno por dos segmentos (7, 8) iguales paralelos entre sí y a la dirección axial de las toberas, teniendo cada segmento (7, 8) dos extremos, un primer y un segundo extremo, estando los dos primeros extremos de cada uno de los segmentos (7, 8) enlazados entre sí mediante una primera línea (9) curva, y estando los dos segundos extremos de cada segmento enlazados entre sí por una segunda línea (10) curva.