baber/WOPTO huggingface dataset:
Patent DK-1456346-T3 (DK)
Inventor: PALLI SUBBA REDDY
IPC: A01N37/28
Filed: 2002-02-20
Granted: 2012-05-29
Abstract: This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a novel ecdysone receptor/invertebrate retinoid X receptor-based inducible gene expression system and methods of modulating gene expression in a host cell for applications such as gene therapy, large-scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.
Patent DK-1434919-T3 (DK)
Inventor: DINCEL BURAK
IPC: E04C2/34
Filed: 2002-10-10
Granted: 2009-04-20
Abstract: An elongated building element (14) to form a series of walls (10) to (13). The elements (14) each have longitudinally extending flanges (21) that snap engage with longitudinally extending grooves (19) in the next adjacent element (14). Accordingly the wall (10) is constructed by joining the elements (14) in a direction transverse their general direction of extension. If so required the elements (14) may be filled with concrete.
Patent DK-1450929-T3 (DK)
Inventor: MEI FENG
IPC: F01N3/02
Filed: 2002-12-05
Granted: 2005-11-21
Abstract: A diesel soot filter medium (11) comprises at least a first (12) and second layer (13). Both first and second layer have a layer volume VLq and a layer filtering surface SLq, where SLq is the accumulation of all mantle surfaces of the fibers present in this layer q. The first layer has a SL1/VL1-ratio of less than 32500m<2>/m<3>, and the second layer has a SL2/VL2-ratio being more than 1.1x SL1/VL1. <IMAGE>
Patent DK-1336708-T3 (DK)
Inventor: TALPE JOSEPH JR
IPC: E05B13/00
Filed: 2003-02-11
Granted: 2010-08-23
Abstract: The lock comprises a frame (5), at least one bolt (4), in particular a latch bolt which projects in a predetermined direction out of the frame, a bolt operating mechanism (26, 31, 32) and means (20, 24) for mounting at least one hand operated actuating element (21) for said bolt operating mechanism on the frame so that this actuating element can rotate on the frame according to a rotation axis (25) extending in particular perpendicular to said predetermined direction. The bolt (4) comprises a shaft portion (38) and at least one laterally projecting lock wing (39) and is rotatably mounted on the frame according to a further rotation axis (37) extending in said predetermined direction, the bolt operating mechanism being arranged to rotate the bolt (4) between a first angular orientation, wherein the lock wing (39) of the bolt is in the locking position, and a second angular orientation, wherein the lock wing of the bolt is in the unlocking position. The latch bolt (4) is made of at least a first (40) and a second part (38) which are screwed onto one another.
Patent DK-1435830-T3 (DK)
Inventor: BROUILLON ANDRE
IPC: A61B1/00
Filed: 2003-03-14
Granted: 2009-03-23
Abstract: A package consists of an outer peelable sachet of a film material to hold a non-metallic blade (L) in sterile conditions. After opening the sachet the blade can be attached to a handle (M). Once it is fastened the sleeve can be turned inside out to cover the handle while the laryngoscope is in use.  A package consists of an outer peelable sachet with an inner sleeve (G) of a film material less than 100 micrometer thick to hold the non-metallic blade (L) in sterile conditions. After opening the sachet the blade can be attached to the handle (M) without touching it. Once it is fastened the sleeve can be turned inside out to cover the handle while the laryngoscope is in use, and after use the sleeve can be turned back over the blade, which can be detached from the handle and disposed of.
Patent DK-1480634-T3 (DK)
Inventor: CHUNG KIWON
IPC: A61K31/56
Filed: 2003-02-06
Granted: 2011-11-14
Abstract: This invention provides a method of treating, preventing, suppressing, inhibiting or reducing the incidence of benign prostate hyperplasia in a male subject, by administering to the subject a selective androgen receptor modulator (SARM) and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or any combination thereof as described herein. This invention also provides a method of treating a subject suffering from hair loss, comprising the step of administering to the subject a therapeutically effective amount of a 5-α reductase enzyme type 1 and/or type 2 inhibitor, wherein said inhibitor is a selective androgen receptor modulator (SARM) and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or any combination thereof as described herein. This invention also provides a method of inhibiting a 5-α reductase type 1 and/or type 2 enzyme, comprising contacting the enzyme with an effective 5-α reductase inhibitory amount of a selective androgen receptor modulator (SARM) and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or any combination thereof, as described herein.
Patent DK-1573058-T3 (DK)
Inventor: VAN BLOKLAND HENRICUS JOHANNES MARIA
IPC: C12N15/63
Filed: 2003-12-02
Granted: 2012-01-16
Abstract: The present invention relates to the production of proteins in a cell or host cell. The invention uses a TRAnscription Pause (TRAP) sequence to enhance a protein expression characteristic of a protein expression unit. The TRAP sequence is thought to prevent, at least in part, formation of antisense RNA or to, at least in part, prevent transcription to enter the protein expression unit. In one embodiment, the invention provides a method for expression of at least one protein of interest in a cell comprising providing the cell with at least one protein expression unit that comprises a promoter functionally linked to an open reading frame encoding at least one protein of interest, characterized in that the protein expression unit further comprises at least one TRAP sequence and wherein the TRAP sequence is functionally located downstream of the open reading frame and at least in part prevents formation of antisense RNA. In another embodiment, the TRAP sequence is functionally located upstream of the promoter and at least in part prevents transcription to enter the expression unit. Preferably, the expression protein unit further comprises at least one STabilizing Anti-Repressor sequence.
Patent DK-1593172-T3 (DK)
Inventor: MELZNER DIETER
IPC: C08J5/22
Filed: 2003-12-19
Granted: 2007-11-12
Abstract: Membrane electrode array (MEA) for polymer electrolyte fuel cell with operating temperature up to 250[deg]C has membrane of basic polymer(s), sandwiched between 2 flat gas distribution electrodes that are charged with dopant and act as dopant reservoir for the membrane. After pressure and heat treatment, the doped membrane is proton-conducting and firmly bound to the electrodes. When doped, its conductivity is not less than 0.1 S/m at a temperature not less than 25[deg]C. Independent claims are also included for the following: (1) polymer membrane for an MEA, consisting of a polymer containing basic polymer(s), with a mechanical stability of over 110 N/mm 2> breaking strength and over 6% elongation at room temperature; (2) polymer electrolyte fuel cells for an operating temperature up to 250[deg]C with the specified MEA between bipolar plates.
Patent DK-1603580-T3 (DK)
Inventor: HELENEK MARY JANE
IPC: A61K31/555
Filed: 2003-05-13
Granted: 2008-10-06
Abstract: A method of treating Restless Leg Syndrome, includes administering to a subject an iron complex having an iron release rate greater than IDI. The iron release rate is determined at a concentration of at least 2,000 mug/dl.
Patent DK-1452122-T3 (DK)
Inventor: GREY NICHOLAS GERALD
IPC: A46B13/02
Filed: 2002-07-19
Granted: 2006-04-03
Abstract: A surface cleaning apparatus comprising a body (1; 106) having a forward compartment (9; 114) with an opening in a lower surface thereof; and an elongate rotatable brush arrangement (11; 116) provided within and extending across the forward compartment (9; 114) of the body (1; 106). The brush arrangement (11; 116) has bristles adapted to extend through the opening in the forward compartment (9; 114) as the brush arrangement (11; 116) is rotated. The lower front region of the body (1; 106) is chamfered to increase the extent to which the bristles protrude from the body (1; 106) in the region of the chamfer such that, when the apparatus is inclined relative to a surface to be cleaned, contact between the bristles and the surface to be cleaned is increased. <IMAGE>
Patent DK-1700317-T3 (DK)
Inventor: LEVY DANIEL N
IPC: B29C48/475
Filed: 2004-12-21
Granted: 2009-02-23
Abstract: The invention provides an insulated wire having a conductor and an insulator of paste extruded PTFE fine powder around the conductor. The paste extruded insulator has at least one closed continuous longitudinal air channel spaced apart from the conductor. The invention further provides a process for forming an insulator around a conductor by paste extruding lubricated PTFE fine powder in an extrusion device comprising a die, mandrel, and at least one channel-forming member. The die and mandrel form a converging chamber leading to an extrusion orifice and the channel-forming member is positioned in the orifice. The mandrel has a central bore for supplying the conductor. Lubricated PTFE fine powder is forced through the chamber and out of the exit of the orifice as a lubricated green extrudate around the conductor forming an insulator with at least one closed longitudinal air channel spaced apart from the conductor.
Patent DK-1596015-T3 (DK)
Inventor: KINTSCHER MATTHIAS DIPL ING
IPC: E04G21/12
Filed: 2005-05-03
Granted: 2011-10-24
Abstract: The device (V) for the fixing and lifting of especially prefabricated reinforced concrete components has a protective box (2) and at least one flexible rope element (S) passing through the box and which has a rope loop (3) and end anchor (4). The rope loop and/or the end anchor of the flexible rope element assumes at least in sections an angle of between 0 and 45 degrees in relation to the base (2') of the protective box, and may be between 5 and 25 degrees.. An independent claim is included for a concrete component, and especially a prefabricated reinforced concrete component.
Patent DK-1688370-T3 (DK)
Inventor: PFAU DIETER
IPC: B65D90/08
Filed: 2005-12-15
Granted: 2008-02-04
Abstract: Container (1) comprises an outer wall (5, 6, 7, 8) which can be detachedly fixed to a frame (4). Preferred Features: The outer wall has several detachable planar wall elements. The container has an opening with a door (9) which pivots outward. The outer wall supports a functional module (10), e.g. a fitting, tool or component cupboard. The outer wall is heat- and sound-insulated. One outer wall is connected via a fixing group to a frame element, e.g. a corner support and/or a cross-piece of the frame.
Patent DK-1737807-T3 (DK)
Inventor: HANSON JOE J
IPC: C07C49/327
Filed: 2005-03-31
Granted: 2012-01-16
Abstract: The present invention provides a method of preparing 1-acetyl-1-chlorocyclopropane from 1,3-dichloro-2-pentanone by reaction with base in the presence of a phase transfer catalyst. The reaction may be run in the presence of an organic solvent and in a continuous or batch process.
Patent DK-1835021-T3 (DK)
Inventor: MIWA TAKEHIRO
IPC: A23K20/00
Filed: 2005-12-28
Granted: 2011-04-18
Abstract: The present invention provides a novel bacterial cell composition which comprises cells of  Butyrivibrio fibrisolvens  having the ability to produce butyric acid, a cultured material thereof or an extract thereof, and a method for inhibiting carcinogenesis, a method for immunostimulating, a method for preventing or treating a pathogen, a method for preventing or treating an inflammatory bowel disease and a method for preventing or treating an allergic disease, which use the same.
Patent DK-1819825-T3 (DK)
Inventor: PANNURI SACHIN
IPC: C07H21/04
Filed: 2005-12-12
Granted: 2010-05-31
Abstract: Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereoselectively one of a pair of chiral amines in which the amino group is bound to a non-terminal, chirally substituted, carbon atom.
Patent DK-2011301-T3 (DK)
Inventor: SONNEGA MARCO ALEXANDER HENK
IPC: H04L29/06
Filed: 2006-07-13
Granted: 2011-10-17
Abstract: A method of and system for secure data transmission between a client and a third party computer arrangement. The method includes authenticating a user of the client by a security server via a communication session; making available a key pair by the security server, the key pair including a public key and a private key; and performing the secure data transmission between the client and the third party computer arrangement while using the key pair. The key pair having a limited life time defined by: a predetermined duration in time, a predetermined number of communication sessions, or a predetermined number of actions.
Patent DK-1816717-T3 (DK)
Inventor: STAMER GERNOT
IPC: H02G3/04
Filed: 2007-01-20
Granted: 2010-10-25
Abstract: The support has a head (2) adjustable against a body (10), and a carriage (20) vertically adjustable at the body. A clamping spring (3) is provided for pressurizing the head against a frame cover. A tensioning device is provided for tensioning the clamping spring, and is supported at the carriage. The tensioning device exhibits an operating lever (30) with a lifting unit (32) for a pressing rod (4) and/or for the clamping spring. The tensioning unit exhibits a clamping unit (31) that clamps the carriage at the body. The carriage comprises a spring guide that is pressed against the body.
Patent DK-1808438-T3 (DK)
Inventor: STEINER SOLOMON S
IPC: C07K1/36
Filed: 2000-06-29
Granted: 2014-10-27
Abstract: A method is provided for purifying a peptide or a protein comprising: providing a peptide or protein composition containing an impurity to be removed; forming a complex of the active agent with a complexing agent thereby displacing the impurity; and, removing essentially all of the impurity from the complex. A composition is provided comprising such a purified peptide complexed with a complexing agent. Microparticles comprising monomeric or dimeric insulin complexed with a complexing agent, wherein the insulin is substantially free of zinc, may be used in medicine to deliver insulin to a patient. Also provided is a formulation for use in medicine comprising insulin complexed with a complexing agent which, when administered to a patient in an effective amount, produces a peak blood insulin concentration in the patient that simulates a normal response to eating, wherein the formulation is suitable for non-intravenous administration.
Patent DK-1860413-T3 (DK)
Inventor: LANTZ LOREN
IPC: G01J5/02
Filed: 2003-01-06
Granted: 2010-08-23
Abstract: A probe cover (20) is provided including a tubular body extending from a proximal end (24) to a distal end (26). The proximal end defines an opening configured for receipt of a distal end of a thermometer The distal end of the tubular body is substantially enclosed by a film (36). The distal end includes at least one end rib (38) disposed about an inner circumference thereof At least one end rib is configured to engage the distal end of the thermometer such that the distal end of the thermometer is spaced apart from the film. The body may extend in a tapered configuration from the proximal end to the distal end. The end rib can include a transverse portion disposed along a surface of the film. The end rib may include a longitudinal portion extending along the body The longitudinal portion may extend proximally along the body and the transverse portion may project along a surface of the film such that the longitudinal portion and the transverse portion cooperate to receive the distal end of the thermometer The body may define at least one longitudinal rib projecting from an inner surface thereof The body may define at least one protuberance projecting from an inner and/or an outer surface thereof The longitudinal rib and/or the protuberances can be configured to facilitate nesting of a second probe cover.
Patent DK-1925638-T3 (DK)
Inventor: SCHRENK VOLKER
IPC: C08J3/18
Filed: 2007-10-24
Granted: 2010-11-01
Abstract: Use of a synthetic wax oxidate (I) having a number-average molecular weight of 300-1000 g/mol measured via high-temperature GPC according to ASTM D 6474-99 and an acid number of 15-60 mg potassium hydroxide (KOH)/g as determined according to DIN 53 402, as a processing aid for molding mass comprising a polar polymer having repeating units, is claimed, where at least 60% of the repeating units contain at least one of ester-, amide-, sulfone- and imide groups. Independent claims are included for: (1) the molding mass comprising the polar polymer and (I) (0.05-1.5 wt.%); and (2) a molding part for optical applications, produced from the molding mass.
Patent DK-1987063-T3 (DK)
Inventor: PETZELBAUER PETER
IPC: A61K38/36
Filed: 2007-02-23
Granted: 2010-01-04
Abstract: The invention relates to peptides and peptide derivatives of the following general Formulas (Ia) and (Ib) as well as in particular anti-inflammatory drugs containing these peptides.
Patent DK-2121920-T3 (DK)
Inventor: NIELSEN LARS SOEGAARD
IPC: C07K16/00
Filed: 2008-02-27
Granted: 2011-11-21
Abstract: The invention relates to a procedure for linking cognate pairs of VH and VL encoding sequences from a population of cells enriched in particular surface antigen markers. The linking procedure involves a multiplex molecular amplification procedure capable of linking nucleotide sequences of interest in connection with the amplification, in particular polymerase chain reaction (multiplex PCR). The method is particularly advantageous for the generation of cognate pair libraries as well as combinatorial libraries of variable region encoding sequences from immunoglobulins. The invention also relates to methods for generation of chimeric human/non-human antibodies and expression libraries generated by such methods.
Patent DK-2270050-T3 (DK)
Inventor: SUPER MICHAEL
IPC: A61K31/00
Filed: 2006-12-21
Granted: 2013-08-12
Abstract: Pharmaceutical compositions comprising specific anti-CD19 B4 antibodies with modified variable regions in combination with chemotherapeutic agents are disclosed. The modified anti-CD19 variable region polypeptides have alterations to one or more framework regions or complementarity determining regions of the heavy chain variable region or light chain variable region, thereby to reduce a T-cell response. Moreover the specific anti-CD19 antibodies are expressed in good yields in YB2/0 cells and elicit improved ADCC.
Patent DK-2418276-T3 (DK)
Title: A microorganism strain for production of recombinant proteins
Inventor: LEONHARTSBERGER SUSANNE DR
IPC: C12N1/00
Filed: 2007-01-29
Granted: 2014-02-24
Abstract: New microbial strain comprises a gene coding for a recombinant protein that is secreted during fermentation and a mutated gene that codes for a host protein and has a mutation such that expression of the host protein is reduced. Independent claims are also included for: (1) producing a microbial strain as above by transforming a host cells with the gene for the recombinant protein, culturing the cell in a fermentation medium so that the recombinant protein and host proteins are secreted into the medium, characterizing the host proteins, and reducing or preventing expression of a gene coding for one of the host proteins; (2) producing a recombinant protein by culturing a microbial strain as above in a fermentation medium and then separating the medium from the cells of the microbial strain.
Patent DK-2256494-T3 (DK)
Inventor: SAIDARA FRANK
IPC: G01N33/487
Filed: 2005-05-20
Granted: 2017-04-10
Abstract: A device, comprising: a sensor input capable of receiving a signal from a sensor, the signal being based on a sensed physiological characteristic value of a user; 
a memory for storing a plurality of measurements of the sensed physiological characteristic value of the user from the received signal from the sensor; and 
a display for presenting a graphical representation of the plurality of measurements of the sensed physiological characteristic value preferably continuously in real time.
Patent DK-2659881-T3 (DK)
Inventor: BUSER THOMAS
IPC: A61K47/36
Filed: 2012-04-30
Granted: 2018-02-05
Abstract: Delayed release of a drug to the colon is achieved from a delayed release formulation comprising a core and a coating for the core. The core comprises a drug and the coating comprises an inner layer and an outer layer. The outer layer comprises a mixture of a first polymeric material which is susceptible to attack by colonic bacteria, and a second polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a third polymeric material which is soluble in intestinal fluid or gastrointestinal fluid, said third polymeric material being selected from an at least partially neutralised polycarboxylic acid and a non-ionic polymer. In embodiments in which the third polymeric material is a non-ionic polymer, the inner layer comprises at least one of a buffer agent and a base. Advantages of formulations according to the present invention include accelerated release of the drug when exposed to colonic conditions and reduction or elimination of a food and/or alcohol effect on drug release after administration.
Patent DK-2591795-T3 (DK)
Inventor: DISNEY MATTHEW D
IPC: A61K38/16
Filed: 2008-02-25
Granted: 2018-05-07
Abstract: Disclosed are RNA targeting compounds having the formula : wherein j is an integer from 1 to 100; each i is the same or different and is zero or an integer from 1 to 100; each Z<SUP>1</SUP> represents the same or different linking moiety; each R<SUP>1</SUP> is the same or different and represents an alkyl group or an aryl group; each Q<SUP>1</SUP> represents the same or different RNA binding ligand; Q<SUP>2</SUP> is an alkyl group; Q<SUP>3</SUP> is a halogen, an alkyl group, an aryl group, or an amine. Also disclosed are RNA targeting compounds that include a polymer backbone and two or more pendant RNA binding ligands that are bound to the polymer backbone. Methods for using the subject RNA targeting compounds to treat myotonic dystrophy and other diseases are also disclosed, as are compounds that can be used to prepare the subject RNA targeting compounds.
Patent DK-0428752-T3 (DK)
Inventor: FUNABIKI MASAKI
IPC: B01D53/94
Filed: 1990-06-08
Granted: 1994-10-03
Abstract: Exhaust gas purificn. catalyst consists of a monolithic support coated with a catalytic layer which contains activated alumina; at least one Pt gp. element (such as rhodium); cerium oxide; a copptd. oxide of zirconium stabilised by cerium; and opt. a zirconium cpd. The copptd. oxide of Zr stabilised by Ce pref. contains 99-75% by wt. (esp. 95-85%) Zr oxide and 1-25% (esp. 5-15%) Ce oxide. The catalyst is produced by coating the support with a slurry contg. the above components, and firing.
Patent DK-0482016-T3 (DK)
Inventor: HEINTKE HANS-EBERHARD
IPC: A45D26/00
Filed: 1990-06-27
Granted: 1995-06-12
Abstract: The invention described has a motor (2) housed in a casing (1), plus a drive device (9, 11, 13) and a plucking head (5). In order to avoid pinching the skin, and for work on small areas of skin and precise contours, the device has a work surface consisting of the end of a hollow cylinder (7) (=the plucking head (5)). Inside the hollow cylinder (7) is a gripping device with gripper arms (16) which are acted on by a rotating cam (19).