baber/WOPTO huggingface dataset:
Patent CA-3071011-A1 (CA)
Title: Methods and compositions for heterologous reprna immunizations
Inventor: VOGELS RONALD
IPC: A61K39/00
Filed: 2018-07-27
Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
Patent CA-3077583-A1 (CA)
Title: Prefabricated part with a concrete body
Inventor: PREDL MANFRED
IPC: F16L9/08
Filed: 2020-04-07
Abstract: ABSTRACT A prefabricated part comprises a concrete body that has the form of a pipe section with two pipe ends and a pipe inner side. The pipe inner side is lined at least in some areas by a lining made of plastic material connected to the concrete body, and at least one of the pipe ends is covered at least in some areas by a molded part made of plastic material connected to the concrete body. At least the pipe end, which is covered at least in some areas, has a connecting joint in order to connect the pipe end to a pipe end of a further prefabricated part. The lining consists of a thermoplastic material and the molded part consists of a thermosetting plastic. The lining and the molded part are connected to each other in a sealed manner. Date reçue/Received Date 2020-04-07
Patent CA-3079917-A1 (CA)
Inventor: VOIX JEREMIE
IPC: A61B5/00
Filed: 2018-10-29
Abstract: A system and method for training a classification module of nonverbal audio events and a classification module for use in a variety of nonverbal audio event monitoring, detection and command systems. The method comprises capturing an in-ear audio signal from an occluded ear and defining at least one nonverbal audio event associated to the captured in-ear audio signal. Then sampling and extracting features from the in-ear audio signal. Once the extracted features are validated, associating the extracted features to the at least one nonverbal audio event and updating the classification module with the association. The nonverbal audio event comprises one or a combination of user-induced or externally-induced nonverbal audio events such as teeth clicking, tongue clicking, blinking, eye closing, teeth grinding, throat clearing, saliva noise, swallowing, coughing, talking, yawning with inspiration, yawning with expiration, respiration, heartbeat and head or body movement, wind, earpiece insertion or removal, degrading parts, etc.
Patent CA-3082843-A1 (CA)
Inventor: SWENSON DAVID CARL
IPC: G01F23/26
Filed: 2019-02-13
Abstract: Un système, tel qu'un moteur avec un carter contenant de l'huile ou un fluide mélangé à de l'huile, a un réservoir contenant un liquide qui s'étend jusqu'à un niveau du fluide. Une structure de support de jauge supporte une jauge sur celle-ci de telle sorte que la jauge s'étend dans le fluide au-delà du niveau du fluide, et de telle sorte que la jauge puisse être retirée manuellement de la structure de support de jauge par un utilisateur. Un système électrique est connecté à la jauge, et le système électrique détecte électriquement le niveau du fluide sur la base d'une caractéristique électrique de la jauge qui varie avec le niveau variable du fluide lorsque la jauge s'étend dans celui-ci. La caractéristique électrique peut être la capacité de la jauge détectée par charge et décharge séquentielles de la jauge pour produire un signal électrique en ondes carrées dont la fréquence correspond au niveau du fluide.
Patent CA-3083794-A1 (CA)
Inventor: JUNGNICKEL UWE
IPC: A46B5/00
Filed: 2018-12-13
Abstract: An oral care implement comprises a head and a handle, the head being repeatedly attachable to and detachable from the handle. The head is at least partially made from a material having a density from about 0.5 g/cm³ to about 1.2 g/cm³, while the handle is at least partially made from a material having a density from about 2.1 g/cm³ to about 3.1 g/cm³.
Patent CA-3083847-A1 (CA)
Inventor: INGHAM ALAN
IPC: C07C29/151
Filed: 2018-11-29
Abstract: A process for the co-production of methanol and ammonia is described comprising the steps of: (a) forming a first synthesis gas stream by reacting a first portion of a hydrocarbon feedstock and steam in a steam reformer, (b) forming a second synthesis gas stream in parallel to the first synthesis gas stream by reacting a second portion of the hydrocarbon feedstock with an oxygen-containing gas and steam in an autothermal reformer, (c) synthesising methanol from a first process gas comprising the first synthesis gas stream, and (d) synthesising ammonia from a second process gas prepared from the second synthesis gas stream, wherein a purge stream containing hydrogen is recovered from the methanol synthesis step (c) and a portion of the purge gas stream is fed to the autothermal reformer and/or the second synthesis gas in step (b).
Patent CA-3086598-A1 (CA)
Title: Systeme hote/secteur optimise pour la production de vaccins protecteurs mono- et multivalents sooun/'i a base de levure kluyveromyces lactis
Inventor: HUHRLIMANN HANS CASPAR
IPC: A61K39/12
Filed: 2018-12-19
Abstract: L'invention concerne des levures recombinantes Kluyveromyces lactis (K. lactis) capables d'exprimer très efficacement une ou plusieurs protéines étrangères et pouvant être utilisées comme vaccin pour produire une réponse immunitaire protectrice contre des agents pathogènes. En particulier, l'invention fournit des souches de K. lactis pour le clonage ciblé d'acides nucléiques codant pour des antigènes étrangers dans le génome de levure de la souche de K. lactis, qui est caractérisée en ce que la souche de K. lactis comporte des cassettes d'expression pour des antigènes étrangers intégrées au locus KIURA3-20 (KLLA0E22771g) et/ou au locus KIMET5-1/ (KLLA0B03938g) en alternative ou en complément au locus K/MC4. L'invention concerne également les vecteurs d'expression intégratifs et les méthodes de production des souches de K. lactis de l'invention et leur utilisation comme vaccins.
Patent CA-3091019-A1 (CA)
Title: Systeme de marchandisage
Inventor: LIM JANE YU XIN
IPC: A47F1/12
Filed: 2019-02-13
Abstract: L'invention concerne un système (1000) permettant d'afficher des marchandises (M) comportant un premier élément de plateau (100) comportant un passage (12) s'étendant à partir d'une première extrémité (106) du premier élément de plateau (100) jusqu'à une seconde extrémité (108) du premier élément de plateau (100). Le passage (12) comporte un lit de support (110) s'étendant parallèlement à un axe longitudinal (AT) du passage (12) et une rampe (112) s'étendant à partir du lit de support (110) jusqu'à la seconde extrémité (108) selon un angle oblique. Le système (1000) comporte en outre un second élément de plateau (200) comportant le passage (12). Le second élément de plateau (200) est reçu par la première extrémité (106) du premier élément de plateau (100) et peut être actionné entre une première position et une seconde position. Dans la première position, le passage (12) présente une première longueur (LE) et dans la seconde position le passage (12) présente une seconde longueur (LR). Le système (1000) comporte en outre un poussoir (300) disposé à l'intérieur du passage (12) et pouvant être actionné entre une première position adjacente à la rampe (112) et une seconde position espacée de la rampe (112).
Patent CA-3092432-A1 (CA)
Title: A container with child resistant means
Inventor: SHEAHAN MARK
IPC: B65D50/04
Filed: 2019-02-22
Abstract: A container (2) with child resistant means, which container (2) comprises: (i) a body portion (4) for receiving a product; (ii) a top (6) for opening and closing the body portion (4); (iii) locking means (10) for locking the top (6) to the body portion (4); (iv) opening means for unlocking the locking means (10) and enabling the top (6) to be moved to open the body portion (4), and the container (2) being such that: (v) the locking means (10) is a push-operated locking means (10) which operates by pushing the top (6) onto the body portion (4); (vi) the opening means (19) is a squeeze-operated opening means (19) which operates by simultaneously squeezing of the top (6) at two opposed locations (19) only; and (vii) the push-operated locking means (10) and the squeeze-operated opening means (19) enable the body portion (4) to be closable and openable using only one hand on the top (6) and without having to rotate the top (6) relative to the body portion (4).
Patent CA-3094241-A1 (CA)
Inventor: SHUSTER JEFFREY
IPC: C07K16/28
Filed: 2019-03-27
Abstract: La présente invention concerne des compositions et des procédés permettant d'identifier des sujets susceptibles de bénéficier de l'utilisation d'un agent thérapeutique. La présente invention utilise la spécificité d'anticorps monoclonaux thérapeutiques pour un épitope unique afin de déterminer si un anticorps monoclonal thérapeutique interagit avec une matière biologique dans/d'un patient. Le complexe cible comprend : 1. un anticorps A, l'anticorps A étant un anticorps monoclonal thérapeutique potentiel, ou un fragment de celui-ci, comprenant (a) une région variable spécifique d'un épitope d'intérêt, et (b) une région constante humaine ; et 2. un anticorps B, l'anticorps B reconnaissant la région constante humaine de l'anticorps A.
Patent CA-3095669-A1 (CA)
Title: Systemes et procedes permettant de carbonater un liquide dans un recipient, et de detecter des niveaux de dioxyde de carbone dans une source de dioxyde de carbone
Inventor: WOOD BARRY P
IPC: B67D1/08
Filed: 2019-03-22
Abstract: La présente invention concerne un système ou un procédé qui permettent de carbonater un liquide et qui incluent la réception, dans un récipient fermé hermétiquement d'un carbonateur d'un système de distribution de boissons, d'une quantité de liquide prédéfinie, l'identification d'un niveau de carbonatation prédéfini associé à une substance aromatisante, et le réglage d'une pression cible du récipient fermé hermétiquement sur la base du niveau de carbonatation prédéfini. La pression cible est sélectionnée parmi une pluralité de pressions cibles différentes. Le système ou le procédé peuvent également comprendre le dégagement de dioxyde de carbone sous pression à partir d'une source de dioxyde de carbone dans ce récipient fermé hermétiquement contenant la quantité prédéfinie du liquide jusqu'à ce qu'une pression interne dudit récipient fermé hermétiquement soit sensiblement égale à la pression cible. Ledit système ou ledit procédé peuvent aussi inclure la distribution, dans un récipient de boisson, de la substance aromatisante et du liquide à partir du récipient fermé hermétiquement du carbonateur.
Patent CA-3097063-A1 (CA)
Inventor: GRICE CHERYL A
IPC: C07D295/205
Filed: 2019-05-14
Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
Patent CA-3097296-A1 (CA)
Inventor: ZOUHRI YOUSSEF
IPC: G06Q50/18
Filed: 2020-10-23
Abstract: A method for determining relevant search results includes provided a searchable database containing a plurality of source documents with corresponding citations. The source documents and the corresponding citations have keywords. The keywords are extracted from the source documents and citations using a parser and are stored in the searchable database in association with the source documents and citations. The citations are linked to their source documents in a graph databased based upon the keywords shared between them.
Patent CA-3097877-A1 (CA)
Inventor: CHALFANT LOUIS
IPC: B25H3/02
Filed: 2020-11-03
Abstract: A tool case for attaching to a belt for storing a multi-tool having an open (or unfolded) position and a closed (or folded) position. The tool case includes a front portion and a back portion. A compartment is formed between the front portion and the back portion and is configured to receive and retain a multi-tool in both the open position and the closed position.
Patent CA-3099055-A1 (CA)
Title: Improved pharmaceutical formulations
Inventor: SONAVANE GANESHCHANDRA
IPC: A61K9/00
Filed: 2019-04-25
Abstract: A free-flowing solid pharmaceutical formulation comprising one or more active ingredients and a blend comprising sorbitol and liquid paraffin, a package containing the formulation, a process for the manufacture of the formulation and the use of the blend in the formulation.
Patent CA-3108806-A1 (CA)
Title: Reagents based on a tertiary amine backbone to introduce chemical functionality in nucleic acids and sequence-controlled polymers
Inventor: SLEIMAN HANADI F
IPC: C07H19/056
Filed: 2019-08-09
Abstract: It is provided an achiral, non-nucleosidic backbone for phosphoramidites that can be inserted with high yields in nucleic acid strands and sequence-controlled oligo(phosphodiester)s through solid phase synthesis (SPS) using a DNA synthesizer. From this backbone, platforms with useful chemical handles were synthesized, further functionalized, transformed into phosphoramidites and attached to nucleic acid strands and sequence-controlled oligo(phosphodiester)s. The backbone is based on a tertiary amine with a 3-6 carbon spacer between the central nitrogen and the two external hydroxyls. The spacer has been optimized to increase coupling yields and stability.
Patent CA-3113311-A1 (CA)
Inventor: GOKE DENNIS
IPC: A01M1/02
Filed: 2019-09-16
Abstract: La présente invention concerne la détection d'arthropodes (organismes bénéfiques et/ou nuisibles) dans une région, dans laquelle poussent des plantes, à l'aide d'une caméra.
Patent CA-3114210-A1 (CA)
Title: Percussion fuse
Inventor: LABENDA THOMAS
IPC: F42C11/02
Filed: 2019-08-27
Abstract: The invention relates to a percussion fuse having an active sensor, which generates a sensor voltage, having a filter circuit consisting of a high pass and at least one low pass, in order to be able to adjust dynamic percussion characteristics. The invention further relates to an operating state switch, which can transition the percussion fuse into one of two operating states, specifically into an activated and a deactivated operating state. To this end, the operating state switch is switched into one of the two operating states by means of a safety voltage. In the active operating state, the sensor voltage is supplied directly to the threshold value switch and in the deactivated operating state, the sensor voltage is held below the threshold value of the threshold value switch by an input limiter.
Patent CA-3117705-A1 (CA)
Title: Baling machine with containment apparatus
Inventor: OLDS EMORY
IPC: B09B3/00
Filed: 2019-10-25
Abstract: A baling machine including a gathering ram and a hopper with a charging chamber is disclosed. The hopper can include a pair of flat doors and an actuator that can move the flat doors to apply compression force to material placed in the hopper. The compression force applied by the flat doors can improve efficiency of the baling machine by increasing the amount of the material compacted by each stroke of the gathering ram.
Patent CA-3124101-A1 (CA)
Inventor: AMMIRANTE MASSIMO
IPC: A61K31/58
Filed: 2019-12-18
Abstract: L'invention concerne des composés de pipéridinedione ayant la structure suivante (I) dans laquelle RN, R1, R2, R3, R4, X, L,V, m, et n sont tels que définis dans la description, des compositions comprenant une quantité efficace d'un composé de pipéridinedione, et des procédés de traitement ou de prévention d'une maladie médiée par un récepteur des androgènes.
Patent CA-3125881-A1 (CA)
Inventor: ZHA SHITONG
IPC: F25B1/00
Filed: 2021-07-26
Abstract: A cooling system implements various processes to improve efficiency in high ambient temperatures. First, the system can flood one or more low side heat exchangers in the system. Second, the system can direct a portion of vapor refrigerant from a low side heat exchanger to a flash tank rather than to a compressor.  Third, the system can transfer heat from refrigerant at a compressor suction to refrigerant at the discharge of a high side heat exchanger.
Patent CA-3127064-A1 (CA)
Title: Production of synthesis gas and of methanol
Inventor: ALAMRO MARWAN
IPC: C01B3/48
Filed: 2020-03-06
Abstract: A system comprising a catalytic partial oxidation (CPO) reactor to produce, from a CPO reactant mixture, a CPO reactor effluent characterized by a hydrogen to carbon monoxide (H2/CO) molar ratio and a M ratio defined as (H<sub>2</sub>-CO<sub>2</sub>)/(CO+C=<sub>2</sub>); a water- gas shift (WGS) reactor configured to produce a hydrogen enriched reactor effluent from at least a portion of the CPO reactor effluent, wherein the hydrogen enriched reactor effluent is characterized by a H<sub>2</sub>/CO molar ratio that is greater than the H<sub>2</sub>/CO molar ratio of the CPO reactor effluent; and a CO<sub>2</sub> separator operable to remove a portion of the CO<sub>2 </sub>from the hydrogen enriched reactor effluent to yield the syngas, wherein the syngas is characterized by a M ratio that is greater than the M ratio of the CPO reactor effluent and of the hydrogen enriched reactor effluent. Processes for producing the syngas and producing methanol therefrom are also provided.
Patent CA-3128953-A1 (CA)
Title: Process for the production of a bio-oil using a rosin-containing oil
Inventor: KUGGE CHRISTIAN
IPC: C10G1/06
Filed: 2020-02-07
Abstract: The present invention relates to a process for producing bio-oil comprising depolymerized lignin using a rosin-containing oil.
Patent CA-3131590-A1 (CA)
Inventor: Wang ji jun
IPC: G01B11/00
Filed: 2020-11-25
Abstract: The present application discloses an overlooking-type golf ball detection method, applied to a golf system with a top camera configured for detecting a golf ball provided with a mark thereon. The method comprises: calibrating a camera: converting an image coordinate system of the camera into a world coordinate system; positioning a golf ball: acquiring coordinate data of the golf ball by performing a global positioning on an entire first frame picture captured by the camera after the ball is served; and for a subsequent frame picture captured by the camera after the ball is served, predicting a falling point range of the golf ball and obtaining a local picture of the frame picture according to the falling point range, and acquiring coordinate data of the golf ball by performing a global positioning on the local picture; calculating parameters; and detecting a rotating speed of the golf ball.
Patent CA-3132204-A1 (CA)
Inventor: WANG MINGHAN
IPC: C07K14/705
Filed: 2020-04-07
Abstract: Chimeric antigen receptors (CARs) specific to F0LR1, vectors encoding the FOLR1 CAR, recombinant host cells comprising the FOLR1 CAR (CAR-Ts or CAR-NKs), and methods of using the CAR-Ts or CAR-NKs to treat a disease associated with the expression of FOLR1 thereof are described. Humanized anti-FOLRl monoclonal antibodies and antigen-binding fragments thereof are also described.
Patent CA-3132550-A1 (CA)
Title: Collagen peptide-based medicament compositions and devices and methods of production and use thereof
Inventor: SCHLUMPF RICHARD E
IPC: C07K14/47
Filed: 2020-04-22
Abstract: The present invention is in the fields of medicinal chemistry, biotechnology and pharmaceuticals. The invention provides compositions comprising one or more collagen mimetic peptides, optionally attached to one or more therapeutic compounds or one or more imaging compounds, for use in methods of treating, preventing, ameliorating, curing and diagnosing certain diseases and physical disorders in humans and veterinary animals, particularly anterior and posterior segment ocular diseases and physical disorders, paraocular and extraocular diseases and physical disorders, and nerve or nervous system diseases and physical disorders, as well as methods of manufacturing such compositions. The invention also provides medical devices comprising one or more such compositions of the invention. The invention also provides methods of use of such compositions and devices in treating and diagnosing certain diseases and physical disorders in humans and veterinary animals, including anterior and posterior segment ocular diseases or disorders, paraocular and extraocular diseases and physical disorders, and nerve or nervous system diseases or disorders.
Patent CA-3136458-A1 (CA)
Title: Health-care device
Inventor: TSAI CHING-FU
IPC: A61H39/04
Filed: 2021-03-31
Abstract: HEALTH-CARE DEVICE ABSTRACT OF THE DISCLOSURE A health-care device includes a work piece having an operating end and a opposite working end to perform a health-care work on a specific part or an acupoint of a body part of a user; a work body at its lower part the operating end is mounted so that a specific working relationship between the working end and the specific part or the acupoint is maintained; and a device positioning piece connected to the work body for maintaining a specific positional relationship between the working end and the specific part or the acupoint. Date Recue/Date Received 2021-10-15
Patent CA-3137179-A1 (CA)
Inventor: VEILLEUX GUY
IPC: B62D21/20
Filed: 2021-10-29
Abstract: Light-weight beam assembly and truck trailer using the same are disclosed herein. The light-weight beam assembly is a beam being a single unitary continuous piece comprising at least two cutouts cut through, at least one vertically extending supporting member and a plurality of reinforcement members. Two beams may be connected by a plurality of transversal members for use in a truck trailer.
Patent CA-3137419-A1 (CA)
Inventor: GRAY GEOF J
IPC: A01B73/02
Filed: 2021-11-03
Abstract: A tillage implement has a frame connectable to a towing vehicle and at least two transverse rows of secondary tillage tools mounted on the frame, the at least two transverse rows comprising a row of main rollers mounted on the frame rearward of all other rows of the at least two transverse rows. The implement also has a transverse row of auxiliary rollers mounted rearward of the row of main rollers, the transverse row of auxiliary rollers independently pivotable vertically about a transverse pivot axis. The implement has at least one ground-engaging wheel. Independent pivoting of the row of auxiliary rollers allows an operator to increase tillage/field finish on the go or as needed.
Patent CA-3140498-A1 (CA)
Inventor: CHAMPION ELISE
IPC: C12P19/34
Filed: 2020-05-26
Abstract: The present invention relates to variants of Terminal deoxynucleotidyl Transferase (TdT), each of which (i) has an amino acid sequence selected from SEQ ID NO8 10-35, or a functionally equivalent sequence, with at least an amino acid substitution at the position corresponding to residue C302 (with respect to SEQ ID NO: 1) or a functionally equivalent residue in SEQ ID NO8 10-35, respectively, (ii) is able to synthesize a nucleic acid fragment without a template and (iii) is able to incorporate a 3'-O-modified nucleotide into the nucleic acid fragment.
Patent CA-3141524-A1 (CA)
Title: Antimalarial hexahydropyrimidine analogues
Inventor: DE HARO GARCIA TERESA
IPC: C07D239/22
Filed: 2020-08-17
Abstract: A series of 2-imino-6-methylhexahydropyrimidin-4-one derivatives, and analogues thereof, substituted in the 6-position by an arylcarbonylaminophenyl or heteroarylcarbonylaminophenyl moiety, being potent inhibitors of the growth and propagation of the Plasmodium falciparum parasite in human blood, are beneficial as pharmaceutical agents, especially in the treatment of malaria.