baber/WOPTO huggingface dataset:
Patent AU-2020203709-B2 (AU)
Title: Treatment of hormonal disorders of growth
Inventor: BECKERS ALBERT
IPC: A61K38/12
Filed: 2020-06-04
Granted: 2022-09-29
Abstract: The present invention refers to a GPR101 inhibitor, antagonist or inverse agonist or inverse 
agonist for use in preventive and/or therapeutic treatment of diseases selected from the group 
consisting of acromegaly and gigantism and to methods for preventive and/or therapeutic treatment 
of diseases selected from the group consisting of acromegaly and gigantism wherein to a subject 
GPR101 inhibitor, antagonist or inverse agonist is administered.  
Further, the present invention provides a GPR101 agonist for use in preventive and/or 
therapeutic treatment of disorders selected from the group consisting of dwarfism, short stature, 
hypopituitarism and a disease of low levels of pituitary hormone secretion and to methods for 
preventive and/or therapeutic treatment of diseases selected from the group consisting of dwarfism, 
short stature, hypopituitarism and a disease of low levels of pituitary hormone secretion wherein to 
a subject GPR101 agonist is administered.  
The present invention also provides GHRH inhibitors, antagonists or inverse agonists and 
GH antagonists for use in the therapeutic treatment of X-linked acrogigantism (X-LAG syndrome).  
In addition, the present invention refers to a method of increasing body mass and/or body 
size of lifestock comprising administering to livestock an effective amount of GPR01 agonist.  
Further, the present invention is directed to a non-human transgenic animal, comprising as 
expressed transgene a gene encoding GPR101 or overexpressing endogenous GPR101 gen.
Patent AU-2020321757-B2 (AU)
Title: Mobile robot and method for calculating moving distance of mobile robot
Inventor: JANG JAEWON
IPC: B25J11/00
Filed: 2020-01-29
Granted: 2023-10-26
Abstract: The present invention relates to a mobile robot and a method for measuring the moving distance of the mobile robot, and to a mobile robot and a method for measuring the moving distance of the mobile robot, the mobile robot comprising: a spin mop which has a laterally rotatable rotation plate so as to slide and move; an encoder, which acquires one or more pieces of data from the rotation plate so as to transmit same to a control unit; a sensing module, which senses an external situation so as to acquire data about a moving distance and/or a moving speed for a predetermined period of time; and the control unit for processing data, and thus calculating a moving distance or a rotation angle from the data acquired by the encoder, and correcting the moving distance or the rotation angle on the basis of the data acquired by the sensing module, so as to calculate an accurate final moving distance or rotation angle.
Patent AU-2020398022-B2 (AU)
Title: Thiazololactam compound as ERK inhibitor and use thereof
Inventor: LI YI
IPC: A61P35/00
Filed: 2020-12-07
Granted: 2023-04-27
Abstract: Provided are a thiazololactam compound, and the use thereof in the preparation of a drug for treating ERK-related diseases. Specially, the present invention provides a compound as shown in formula (III) or a pharmaceutically acceptable salt thereof.
Patent AU-2021200140-B2 (AU)
Title: Pyrazole derivatives as plasma kallikrein inhibitors
Inventor: DAVIE REBECCA LOUISE
IPC: C07D403/06
Filed: 2021-01-12
Granted: 2022-06-02
Abstract: The present invention provides a selection of compounds of formula (1) and includes compositions 
comprising such compounds, the use of such compounds in therapy (for example in the treatment or 
prevention of disease or condition in which plasma kallikrein activity is implicated), and methods of 
treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.  
A R6 I 
O&Z-R5 
/ H R7 N 
0 B 
Formula (1)
Patent AU-2021215172-B2 (AU)
Title: Accelerated scrolling and selection
Inventor: ALONSO RUIZ MARCOS
IPC: G06F3/048
Filed: 2021-08-11
Granted: 2022-11-17
Abstract: The present disclosure includes generally relates to scrolling and selecting items. An 
electronic device having a display and a touch-sensitive surface displays a user interface with 
a list of items. The items can be scrolled and selected using different techniques. Some 
embodiments include a technique for entering an edit mode to select and scroll items on the 
user interface. Some embodiments include a technique for scrolling to select items on the 
user interface. Some embodiments include a technique for displaying a scroll progress 
indicator for scrolling items on the user interface.
Patent AU-2021308755-B2 (AU)
Title: Scaling method based on a pointwise superposition procedure and system thereof
Inventor: PALLADINO MARCO
IPC: G06F30/23
Filed: 2021-07-12
Granted: 2023-11-02
Abstract: A scaling method for simulating any manufacturing process employing a moving heat source is disclosed. The method is intended to melt or sinter a material, wherein the heat source is driven according to a defined path. The method requires a meso-scale model, which evaluates the physical quantities representative of the process-induced thermal history and residual stress and strain fields for each set of process parameters employed for the given material. The meso-scale results, obtained by modeling one or multiple scan lines, are transferred to the elements of the macro-scale finite element mesh based on the defined path. The scaling is performed pointwise and followed by an averaging operation on the values of the physical quantities computed inside each element of the macro-scale finite element mesh. Finally, a macro-scale simulation is executed for evaluating the residual stresses and distortions arising throughout the entire manufacturing process.
Patent AU-2022202210-B2 (AU)
Title: Systems And Methods For Using Solid High-Level Disinfection Chemistries To Produce Disinfectant Solutions
Inventor: MATTA JOHN
IPC: A61L2/18
Filed: 2022-03-31
Granted: 2023-08-03
Abstract: S.N -' 
jY;' F; 
112 
HP~T~ ~ rr~iF TER 
41PUMP 
FIG. 1 
Systems and methods for using solid high-level disinfection chemistries to producing 
disinfectant solutions. In an embodiment, an apparatus comprises: a first container 
and a second container. The first container is configured to receive water, sodium 
percarbonate and tetraacetylethylenediamine. The water, the sodium percarbonate, 
the tetraacetylethylenediamine react within the first container to produce a mixture 
comprising peroxyacetic acid. The second container is in fluid communication with 
the first container, wherein the second container is configured to receive an acid and 
the mixture. The mixture and the acid mix in the second container to produce a 
disinfectant solution having a pH between 5.0 and 7.0.
Patent JP-5088983-B2 (JP)
IPC: A01N37/32
Filed: 2000-04-14
Granted: 2012-12-05
Abstract: Binders (I) that consist of alkyd resins based on vegetable oils and/or acrylate dispersions and have a pH of 7 or less in w are used to stabilize hydrolysis-sensitive active ingredients in aqueous systems. Independent claims are also included for the following: (1) aqueous systems comprising at least one hydrolysis-sensitive active ingredient in combination with (I); (2) use of (I) in combination with hydrolysis-sensitive active ingredients to protect aqueous systems against microbial att and (3) (I) in combination with hydrolysis-sensitive active ingredients.
Patent JP-4707798-B2 (JP)
IPC: C07C209/54
Filed: 2000-05-29
Granted: 2011-06-22
Abstract: Process for the production of diaminodiphenylmethane and its higher homologues products, which comprises reacting aniline, or one of its derivatives, and formaldehyde, or a compound capable of producing formaldehyde under the reaction conditions, in the presence of a zeolite in acid form having a spaciousness index ranging from 2.5 to 19.
Patent JP-4838410-B2 (JP)
IPC: C25C7/00
Filed: 2000-06-09
Granted: 2011-12-14
Abstract: Electrolysis cell comprises a moving alkali metal amalgam-containing anode, an alkali metal ion-conducting solid electrolyte, and a cathode. The solid electrolyte and the cathode are separated from each other by a liquid electrolyte.
Patent JP-3922425-B2 (JP)
IPC: G07D9/00
Filed: 2000-08-30
Granted: 2007-05-30
Abstract: The present invention provides a bill receiving/processing machine, which has a simple configuration having no temporary reserving section, and has no need of manually sorting the approved bill even in the case where a fault is generated, and can rationally carry out cancel processing with respect to a transaction such that a bill has been already sent to a stacker after money kind discriminating/counting handling is completed. The bill receiving/processing machine is characterized by including: a fault detection means for detecting a generation of fault in money receipt transaction after second time excluding the first time transaction; an alarm means for giving an alarm such that a fault is detected by the fault detection means; and a fault recovery processing section which again places the bill on the hopper when the alarm means gives the alarm of a generation of fault, receives the total bill adding a bill of the present money receipt transaction and a approved bill before the money receipt transaction in the stacker in accordance with the money kind, and distinguishes a received money data of the present money receipt transaction from a received money data of the previous money receipt transaction. <IMAGE>
Patent JP-4707828-B2 (JP)
IPC: B65H29/68
Filed: 2000-12-14
Granted: 2011-06-22
Abstract: The system has a circulating braking belt (24) performing periodic deceleration and acceleration phases with a braking section (24.1) that passes over a suction region (27.1) of a suction mechanism acting through the braking section. The suction region is covered by a sheet (3) deposited on the braking section throughout a deceleration phase. Independent claims are also included for the following: a sheet processing rotation printing machine.
Patent JP-3520260-B2 (JP)
IPC: H01T13/46
Filed: 1998-07-08
Granted: 2004-04-19
Abstract: A very unique universal bi-directional firing spark plug for any spark-ignited internal combustion engine is described. This spark plug eliminates misfire and improves gas mileage, peaks engine performance, horsepower, and increases the RPM range. This unique spark plug is made of an elongated or non-elongated body with an electrical connector at one end. An absolute aerodynamic semispherical dome or sphere electrode is secured to the other end of the body. At least one absolute aerodynamic semicircular electrode is also secured to the body adjacent to the dome or sphere electrode such that the semicircular electrode has its inner surface equidistantly spaced from the dome or sphere electrode's surface. The electrodes can be fabricated from various metals, alloys, and/or precious metals and can also be coated with various metals, alloys, and/or precious metals. Alternate embodiments of the invention include two, three or four or more semicircular electrodes, all of which have a surface equidistantly spaced from the aerodynamic semispherical dome or sphere electrode along its complete arc length.
Patent JP-4380912-B2 (JP)
IPC: C10M129/18
Filed: 1998-09-14
Granted: 2009-12-09
Abstract: Products formed from polycarboxylic acids and epoxides form useful lubricity additives.
Patent JP-3517642-B2 (JP)
IPC: G01N33/50
Filed: 1999-03-18
Granted: 2004-04-12
Abstract: The present invention concerns a method for the determination of apoptotic products in samples taken from patients in which apoptosis is induced as a result of disease or therapy, which is characterized in that the concentration of the apoptotic products in samples taken from patients is correlated with the effectiveness of the therapy and thus serves as a follow-up for the therapy. The present invention in particular concerns a method in which the concentration of nucleosomes is determined in serum samples of tumour patients in order to assess the effectiveness of tumour therapy. Furthermore the present invention also concerns the use of a method according to the invention to determine the effectiveness of therapy in tumour patients who are subjected to a radiotherapy or chemotherapy treatment as well as in patients after an acute ischaemic event or after hypothermia treatment.
Patent JP-4357122-B2 (JP)
IPC: G01N21/17
Filed: 1999-12-13
Granted: 2009-11-04
Abstract: A moisture sensor for detecting moisture on the surface of a transparent material. The moisture sensor includes one or more emitters for producing emitter signals which are influenced by moisture on the transparent material, and one or more detectors for receiving the emitter signals. The detector produces a detector output signal which is filtered and amplified in a pre-demodulation gain and filtering circuit to remove some of the unwanted signal components including noise from ambient light and EMI. Digital Signal Processing filtering is used after the moisture signal is demodulated to a dc signal to discern small signal changes due to moisture events in the presence of large amounts of the noise created by the pre-demodulation gain circuit. The DSP filtering includes a low pass filter stage and a band pass filter stage implemented by a microcomputer using First In First Out shift registers, summing elements and division elements.
Patent JP-4615732-B2 (JP)
IPC: C08L83/04
Filed: 2000-01-31
Granted: 2011-01-19
Abstract: Curable liquid silicone rubber compositions that are curable to form silicone elastomers which are useable as fire resistant sealants. These compositions have low heat release and form hard chars on burning, and comprise:(A) a liquid polyorganosiloxane polymer described by the formula where each R1 is independently selected from the group consisting of alkyl, alkenyl, aryl, and halogenated alkyl groups having from 1 to 18 carbon atoms, each R2 is independently selected from the group consisting of hydroxyl, alkoxy, alkenyl, and alkynyl groups, and x is an integer having a value of from about 10 to 1500,(B) a cross-linking organosilicon compound having at least 3 silicon-bonded reactive groups,(C) a catalyst capable of promoting the reaction between the silicon-bonded R2 groups of Component A and the silicon-bonded reactive group of Component B,(D) wollastonite, and(E) an optional reinforcing filler.
Patent JP-4112181-B2 (JP)
IPC: A61F9/007
Filed: 2000-02-22
Granted: 2008-07-02
Abstract: A mini capsulorhexis valve device is composed of a curved, flexible discoid flap-valve member shaped to align with an ocular lens capsular bag inner surface, and a curved, flexible retainer member shaped to align with an ocular lens capsular bag outer surface, the curved, flexible retainer member being attached at a fastening point to the curved, flexible discoid flap-valve member. Attachment of the curved, flexible discoid flap-valve member to the curved, flexible retainer member may be via bonding with a silastic adhesive. In a method of accessing an ocular lens, the mini capsulorhexis valve device establishes a portal controlling access to an ocular lens. The method may include inserting a cannula through the mini capsulorhexis valve device to permit removal of a crystalline lens matrix and replacement thereof with a capsular filling material. The method may also include injecting a cytotoxic agent into a lens capsule, during which leakage of the injected cytotoxic agent is prevented by the mini capsulorhexis valve device. The method may further include adjusting the refractive power of capsular filling material by adding or removing capsular filling material from the lens capsule during lens replacement surgery or post-surgically.
Patent JP-5255741-B2 (JP)
IPC: G02B5/18
Filed: 2000-05-19
Granted: 2013-08-07
Abstract: A multilayer surface comprising at least two layers, said layers having different refractive indexes such that selective wavelengths/colours are transmitted and or reflected. The layers are preferably laid onto a transparent substrate. The surface can be used as an anti-counterfeit device. A method of determining whether an article is counterfeit comprising: providing such a surface; determining its transmission/absorption characteristics of particular colour(s); matching these up with the expected characteristics to determine whether the surface is counterfeit. This may comprise observing the reflected or transmitted colour at two different angles of incidence or detecting changes in the polarisation state of transmitted light.
Patent JP-4687936-B2 (JP)
IPC: G10L13/08
Filed: 2001-03-22
Granted: 2011-05-25
Abstract: The present invention relates to a voice output apparatus capable of, in response to a particular stimulus, stopping outputting a voice and outputting a reaction. The voice output apparatus is capable of outputting a voice in a natural manner. A rule-based synthesizer 24 produces a synthesized voice and outputs it. For example, when a synthesized voice "Where is an exit" was produced and outputting of the synthesized voice data has proceeded until "Where is an e" has been output, if a user taps a robot, then a reaction generator 30 determines, by referring to a reaction database 31, that a reaction voice "Ouch!" should be output in response to being tapped. The reaction generator 30 then controls an output controller 27 so as to stop outputting the synthesized voice "Where is an exit?" and output the reaction voice "Ouch!". Thereafter, the reaction generator 30 controls the read pointer of a buffer 26 controlled by the read controller 29 such that the outputting of the synthesized voice is resumed from the point at which the outputting was stopped. Thus, the synthesized voice "Where is an e, Ouch!, xit?" is output. <IMAGE>
Patent JP-3340728-B2 (JP)
IPC: C08F4/60
Filed: 2001-08-03
Granted: 2002-11-05
Abstract: High activity, stereoregular olefin polymerization catalysts are produced from an organoaluminum cocatalyst, a selectivity control agent and a procatalyst obtainable from a magnesium-containing, titanium-containing procatalyst precursor also containing at least one of alkoxide, optionally substituted phenoxide or trialkylborate moieties. The catalysts are useful in the polymerization or copolymerization of lower α-olefins, particularly propylene.
Patent JP-3464655-B2 (JP)
IPC: C07B61/00
Filed: 2001-08-08
Granted: 2003-11-10
Abstract: A process for the production of a hydro(halo)fluorocarbon which comprises heating an  alpha -fluoroether in the vapor phase at elevated temperature.  alpha -fluoroethers are obtained by reacting a non-enolizable aldehyde with hydrogen fluoride to form an intermediate and reacting the intermediate with an alcohol or a halogenating agent. Novel  alpha -fluoroethers are also provided.
Patent JP-4033675-B2 (JP)
IPC: F03D80/10
Filed: 2000-07-08
Granted: 2008-01-16
Abstract: Rotor blades for wind power installations of varying design configurations are known. Irrespective of the geometrical configuration of the rotor blades, all rotor blades are generally of a uniform color; typically. The rotor blades of the present invention better integrate a wind power installation into the landscape view, to improve environmental compatibility and to reduce the impact of the foreign body. That is to be achieved in particular in respect of installations with large rotor diameters (more than 40 m). A rotor blade comprising a rotor blade connection and a rotor blade tip and a surface which is arranged therebetween and which is divided into at least two regions which differ in respect of lightness and of which the lighter region is arranged closer to the rotor blade connection than the darker region which is of a natural shade and/or daylight sky shade and/or background shade.
Patent JP-5296279-B2 (JP)
IPC: C08F285/00
Filed: 2000-12-21
Granted: 2013-09-25
Abstract: Foamable modified polystyrene resin particles which are foamable modified polystyrene resin particles (d) comprising modified polystyrene resin particles (c) containing a blowing agent (e); the modified polystyrene resin particles (c) comprising a polystyrene resin and rubber polymer particles (b) being dispersed in the resin, wherein the rubber polymer particles (b) are dispersed uniformly throughout a continuous phase of the polystyrene resin or in a state of a density of the particles (b) being higher in a center portion of the resin particle than in a surface layer portion thereof, and the modified polystyrene resin particles (c) are modified polystyrene resin particles prepared by impregnating a monomer mixture consisting essentially of a styrene monomer and a conjugated diene monomer and comprising the styrene monomer in a larger amount than the conjugated diene monomer, into polystyrene resin particles (a) and carrying out copolymerization.
Patent JP-4845076-B2 (JP)
IPC: A61P29/00
Filed: 2001-02-15
Granted: 2011-12-28
Abstract: The invention relates to a series of pyrrolopyrimidinone derivatives of the formula ( 1 ): wherein R<SUP>1 </SUP>is H; C<SUB>1</SUB>-C<SUB>3 </SUB>alkyl optionally substituted with one or more fluoro atoms; or C<SUB>3</SUB>-C<SUB>6 </SUB>cycloalkyl; R<SUP>2 </SUP>is H; a halogen atom; C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl optionally substituted with OH, C<SUB>1</SUB>-C<SUB>3 </SUB>alkoxy, C<SUB>3</SUB>-C<SUB>6 </SUB>cycloalkyl, or with one or more fluoro atoms; C<SUB>3</SUB>-C<SUB>6 </SUB>cycloalkyl; C<SUB>2</SUB>-C<SUB>6 </SUB>alkenyl; or C<SUB>2</SUB>-C<SUB>6 </SUB>alkynyl; R<SUP>3 </SUP>is H; C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl optionally substituted with OH, C<SUB>1</SUB>-C<SUB>3 </SUB>alkoxy, C<SUB>3</SUB>-C<SUB>6 </SUB>cycloalkyl, or with one or more fluoro atoms; C<SUB>3</SUB>-C<SUB>6 </SUB>cycloalkyl; C<SUB>2</SUB>-C<SUB>6 </SUB>alkenyl; or C<SUB>2</SUB>-C<SUB>6 </SUB>alkynyl; R<SUP>4 </SUP>is C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl optionally substituted with C<SUB>3</SUB>-C<SUB>6 </SUB>cycloalkyl or with one or more fluoro atoms; C<SUB>2</SUB>-C<SUB>6 </SUB>alkenyl; C<SUB>2</SUB>-C<SUB>6 </SUB>alkynyl; or C<SUB>3</SUB>-C<SUB>6 </SUB>cycloalkyl; and R<SUP>5 </SUP>is SO<SUB>2</SUB>NR<SUP>6</SUP>R<SUP>7</SUP>; NHSO<SUB>2</SUB>NR<SUP>6</SUP>R<SUP>7</SUP>; NHCOCONR<SUP>6</SUP>R<SUP>7</SUP>; NHSO<SUB>2</SUB>R<SUP>8; </SUP>NHCOR<SUP>8; </SUP>or phenyl or heterocyclyl either of which is optionally substituted with one or more fluoro atoms or C<SUB>1</SUB>-C<SUB>3 </SUB>alkyl.
Patent JP-5568701-B2 (JP)
IPC: C08F2/00
Filed: 2001-03-02
Granted: 2014-08-13
Abstract: The present invention relates to a method for reducing/suppressing sheeting or agglomerates during polymerisation of olefins, especially during the fluidised bed gas phase polymerisation of olefins. In particular, the present invention relates to a method for reducing/suppressing sheeting or agglomerates during the product grade transition and/or catalyst transitions occurring during polymerisation of olefins.
Patent JP-4796732-B2 (JP)
IPC: C07D413/12
Filed: 2001-04-27
Granted: 2011-10-19
Abstract: Provided herein are novel and useful compounds having a tryptase inhibition activity, pharmaceutical compositions comprising such compounds, and methods treating subjects suffering from a condition, disease, or disorder that can be ameliorated by the administration of an inhibitor of tryptase, e.g., asthma and inflammatory diseases, to name only a few.