baber/WOPTO huggingface dataset:
Patent CA-2447690-A1 (CA)
Title: Kindling fluorescent proteins and methods for their use
Inventor: CHUDAKOV DMITRY
IPC: C07K14/435
Filed: 2002-05-24
Abstract: Kindling fluorescent protein compositions and nucleic acids encoding the same, as well as methods for using the same, are provided. The kindling fluorescent proteins are characterized in that they become brightly fluorescent proteins, from an initial non-fluorescent or low fluorescent state, upon exposure to a kindling stimulus, which fluorescent state may be reversible or irreversible.  The subject protein/nucleic acid compositions find use in labeling protocols, e.g., in labeling proteins, organelles, cells and organisms, etc., in a variety of different types of applications. Also provided are systems and kits for use in practicing such applications.
Patent CA-2451251-A1 (CA)
Title: Spray-applied cellulose insulation and method
Inventor: LANTHIER ALAIN
IPC: F16L59/04
Filed: 2003-11-27
Abstract: A spray-on cellulose insulation and method of application is described herein. The insulation comprises cellulose and an adhesive having gelling properties during application, preferably polyvinyl alcohol. The cellulose includes an additive which triggers gelling of the adhesive upon application to the cellulose. The cellulose preferably also includes a crosslinker for the adhesive. The additive and the crosslinker may be the same, which means the crosslinker is sufficiently alkaline to also trigger the gelling of the adhesive upon application of the adhesive to the cellulose. The gelling of the adhesive allows a reduction in the level of moisture added to the cellulose fibres to below 20%, resulting in an insulation with rapid drying times, reduced risk for fungal growth, lower applied densities and a total moisture content below 30% on an oven dry basis.
Patent CA-2454241-A1 (CA)
Title: Pneumatic construction or bridging element
Inventor: TO FREDERICK E
IPC: E01D15/12
Filed: 2002-03-27
Abstract: The structural or bridge element is constructed from a sheath (1) made of textile fabric, preferably of low extensibility, which is covered in an airtight manner with a flexible plastic. Secured longitudinally within the sheath 1 are a plurality of textile webs of low extensibility in an assembly of mutually parallel planes. The thread profile of first layers 4 of the fabric of the webs 3 is turned through approximately 45° in relation to the longitudinal axis of the bridge element. Second layers 5, each arranged within the same web 3 as the first layer 4, have a thread profile which is selected to be parallel and perpendicular to the longitudinal axis of the bridge element. Bars 6 are arranged on the outside of the sheath 1, respectively in each plane of the webs 3, and are secured within shackles on the sheath 1. The sheath 1 is supplied with compressed air within the range of a few 100 mB.  Wherever the bridge element is laid onto the ground of a cutting 8, the sheath 1 is strengthened by means of a protective covering 9.     Fig. 1
Patent CA-2454860-A1 (CA)
Title: Hybrid interferon/interferon tau proteins, compositions and methods of use
Inventor: LI WAYNE
IPC: C07K19/00
Filed: 2002-08-12
Abstract: The present invention relates to hybrid interferon fusion proteins formed of an interferon-.alpha. protein where the C-terminal region of the interferon- .alpha. protein is replace by C-terminal region of interferon-.tau.. Also described are nucleic acid sequences encoding the interferon fusion proteins , expression vectors containing such sequences, and therapeutic applications o f the interferon fusion proteins. The therapeutic applications include antiviral, anticellular proliferation, and anti-inflammatory applications. O ne advantage of the interferon fusion polypeptides of the present invention is that they have lower cytotoxic side effects when used to treat cells.</SDOAB >
Patent CA-2454938-A1 (CA)
Title: Servo-valve control device and servo-valve control system with abnormality detection
Inventor: YAKUSHI KOJI
IPC: F02D41/20
Filed: 2004-01-07
Abstract: A servo-valve control device for controlling servo-valve opening. The servo-valve opening follows a target by inputting signals of a servo-valve opening target value and of an actual servo-valve opening. The control device has a controller, which is constructed to receive a signal of difference between the servo-valve opening target value and the actual servo-valve opening, and to generate a servo command signal for driving the servo valve. The control device also has an extended observer, which is constructed to receive the actual valve opening signal and the servo command signal, and to estimate an input-terminal disturbance signal added on the servo valve. The control device also has a modification part, which is constructed to modify the servo command signal by subtracting the estimated input-terminal disturbance signal output from the extended observer, from the servo command signal.
Patent CA-2456035-A1 (CA)
Inventor: CALS-GRIERSON MARIE-MADELEINE
IPC: A61K31/44
Filed: 2004-01-29
Abstract: La présente invention concerne l'utilisation de N-arylméthylène éthylènediaminetriacétates, N-arylméthylèneiminodiacétates ou N,N'-diarylméthylène éthylènediamineacétates, leurs sels ou complexes métalliques, pour augmenter la production de monoxyde d'azote dans ou sur la peau ou le cuir chevelu ou les muqueuses ainsi qu'un procédé d'application de monoxyde d'azote dans ou sur la peau, le cuir chevelu ou les muqueuses. Elle concerne également un procédé de traitement cosmétique mettant en ouvre ces composés, en tant que donneurs de NO.
Patent CA-2456703-A1 (CA)
Title: Method of skin exfoliation with the use of a phosphosugar
Inventor: COLLINS DONALD F
IPC: A61Q19/08
Filed: 2002-08-07
Abstract: The invention relates to a method for the exfoliation of skin, comprising applying to the skin a composition containing an effective amount of a phosphosugar. The invention also relates to a method for increasing glycosaminoglycan levels in skin, comprising applying to the skin a composition containing an effective amount of a phosphosugar. In a preferred embodiment, the phosphosugar is mannose-6-phosphate.
Patent CA-2458486-A1 (CA)
Inventor: GORDON DAVID
IPC: A47G21/00
Filed: 2002-08-26
Abstract: A plastic cutlery item (10, 20, 30), fabricated primarily from a plastic material, such as polystyrene, having a metallic coating (14, 24, 34) that imparts to the cutlery item the appearance of metal cutlery or silverware. T he plastic cutlery or tableware items are molded using traditional injection molding techniques, and subjected to a vacuum metallizing process in an individualized non-contiguous manner, where a thin metallic layer is deposit ed on at least one of their surfaces. In the most preferred embodiment of the invention the plastic cutlery or items are molded from a light-transmitting grade of Polystyrene resin and are coated with a thin stainless steel layer through vacuum sputtering deposition on only one of the surfaces.
Patent CA-2459824-A1 (CA)
Title: Cleaning composition with terpene and hydrogen peroxide
Inventor: JOHNSON LOUIS B
IPC: C11D1/22
Filed: 2004-03-05
Abstract: A cleaning composition uses a terpene such as D-limonene or orange oil, a nonionic surfactant, a single anionic surfactant, an anti-oxidant, hydrogen peroxide, and the balance deionized water.
Patent CA-2466443-A1 (CA)
Title: Traitement selectif des tumeurs exprimant l'interleukine 13
Inventor: PURI RAJ
IPC: A61K47/48
Filed: 2002-11-08
Abstract: La présente invention concerne une méthode de traitement de tumeurs qui expriment un récepteur de l'interleukine 13 (IL-13). La méthode consiste à introduire directement dans la tumeur, une cytotoxine qui a pour cible le récepteur Il-13. L'agent cytotoxique peut être introduit par un moyen d'apport potentialisé par la convection au moyen d'un cathéter approprié ou d'un autre dispositif. Lorsqu'on utilise un cathéter potentialisé par la convection, la méthode implique de positionner la pointe d'au moins un cathéter au voisinage immédiat de la tumeur. Une fois le cathéter positionné, ce dernier est connecté à une pompe qui envoie l'agent actif au cathéter qui l'apporte, par sa pointe, à la tumeur. Un gradient de pression produit par la pointe du cathéter est maintenu pendant la perfusion.
Patent CA-2467393-A1 (CA)
Title: Tubular core assemblies for rolls of paper or other sheet material
Inventor: KEWIN DANIEL D
IPC: B65H75/18
Filed: 2004-05-17
Abstract: A tubular core assembly for a roll of paper or other sheet material has a hollow cylindrical core member of metal or plastic material, the core member having at least one lug projecting radially inwardly from an inner surface thereof adjacent to each end of the core member. Each lug is longitudinally spaced from the respective adjacent end of the core member, and an annular plastic end member is located within each opposite end portion of the core member and is a friction fit therein.  Each end member has a notch at its longitudinally inner end receiving the lug adjacent to the respective end of the core member to facilitate transmission of torque and axial chuck pressure from the end members to the core member.
Patent CA-2468138-A1 (CA)
Title: Semi-trailer suspension air spring control system
Inventor: PIERCE PHILLIPPI R
IPC: B60G17/005
Filed: 2002-12-17
Abstract: An automatic pneumatic control system (30) for the air springs (16) of a semi-trailer air-ride trailing beam-type axle/suspension system (11). A plurality of conduits (38,42,44) and valves (32,35,41,43) of the control system pneumatically interconnect one or more sources of compressed air (31,39), the vehicle parking brakes (37) and the suspension air springs (16). The control system (30) incorporates a vented two-position two-way pilot valve (52) for controlling inflation and deflation of each air spring (16). The valve (52) closes when air pressures in a pair of control system sensor lines (45,51) differ, thereby enabling complete or nearly complete deflation of the air spring (16) it controls before the parking brake (37) is set, thereby minimizing or eliminating the problems of trailer drop and walk during loading of an empty trailer, heretofore caused by complete or nearly complete deflation of the air springs (16) only after the parking brakes (37) are already set.
Patent CA-2468352-A1 (CA)
Title: Cast parts with enhanced wear resistance
Inventor: PONCIN CLAUDE
IPC: B22D19/00
Filed: 2002-09-30
Abstract: The invention concerns a cast wear part with its structure reinforced by at least a type metal carbide, and/or metal nitride, and/or boride, and/or metal oxides, and/or intermetallic compounds, referred to below as constituents. The invention is characterized in that the raw materials used as reagents for said constituents have been introduced in a mould (1) before casting in the form of compacted powder inserts or preforms (3) or the form of slurries (4), and the reaction of said powders has been activated in situ by casting a metal, forming a porous conglomerate in situ, and said metal has infiltrated the porous conglomerate, thus forming a reinforced structure leading to inclusion of said constituents in the structure of the metal used for casting, thereby creating a reinforcing structure on the wear part (2).
Patent CA-2468553-A1 (CA)
Inventor: UCHIYAMA HIROMI
IPC: B26B19/04
Filed: 2004-05-27
Abstract: An outer cutter formed with hair introduction slits and attached to an electric shaver in a substantially inverted U-shape, in which recessed portions, in which the shaving surface side of the outer cutter is recessed, are provided adjacent to one or both end portions of the slits, so that the end portions of the slits are formed as hair introduction openings that introduce hair.
Patent CA-2468860-A1 (CA)
Inventor: CLARK CHRISTOPHER J
IPC: G01R31/3185
Filed: 2002-11-12
Abstract: An embedded electronic sxstem built-in self-test controller architecture that facilitates testing and debugging of electronic circuits and in-system configuration of programmable devices. The system BIST controller architecture includes an embedded system BIST controller, an embedded memory circuit, an embedded IEEE 1149.1 bus, and an external controller connector. The system BIST controller is coupled to the memory circuit and the IEEE 1149.1 bus, and coupleable to an external test controller via the external controller connector. The external test controller can communicate over the IEEE 1149.1 bus to program the memory and/or the system BIST controller circuitry, thereby enabling scan vectors to be debugged by the external test controller and then downloaded into the memory for subsequent application to a unit under test by the system BIST controller.
Patent CA-2469601-A1 (CA)
Inventor: DOBSON PHIL
IPC: A01K61/00
Filed: 2004-06-02
Abstract: The present invention provides for an off-shore unitary fish farming apparatus, comprising: a plurality of floatable fish containers aligned sequentially having attachment means for flexibly connecting the containers to maintain the containers in a predetermined relationship to one another, a dampening means attached to at least one of the containers to reduce current and wave and also deflect any floating debris away from the containers, a fish feed tank for holding, mixing and distribution of fish feed slurry to each of the plurality of fish containers, the fish tank having a securing means for attaching the dampening means to the tank; a feed dispenser for radially dispensing fish feed in the container directly beneath the water surface, anchor means to anchor the apparatus to an aquatic floor, the anchor means allowing radial movement of the tank around an anchor position and a crane mounted on the fish feed tank.
Patent CA-2470221-A1 (CA)
Title: Pressure-cast component made of highly ductile and resilient aluminium ally
Inventor: BRUSETHAUG STIG
IPC: B22D17/00
Filed: 2002-12-17
Abstract: The invention concerns a component, in particular a safety, structural or ground connection component of a motor vehicle, cast under pressure made of an aluminium alloy with the following composition (in wt. %): Mg: 1.0-4.5; Si: 0.2-1.3; Cu < 0.3; Zn < 0.1; Fe < 0.3, Ti < 0.3 and at least an element for reducing adherence to the mould: Mn (0.3-1), Cr (0.1-0.4), Co (0.1-0.4), V (0.1-0.4) and Mo (0.1-0.4), other elements < 0.05 each and 0.15 in total, the rest being aluminium.
Patent CA-2470519-A1 (CA)
Title: Heteroaryl substituted pyrrole modulators of metabotropic glutamate receptor-5
Inventor: SMITH NICHOLAS D
IPC: A61P25/20
Filed: 2002-12-17
Abstract: Pyrrole compounds selected from the group consisting of 3-(1-pyridin-2-yl-1H-pyrrol-3-yl)benzonitrile;  2-[3-(3-chlorophenyl)-1H-pyrrol-1-yl]pyridine;  2-[3-(3-methoxyphenyl)-1H-pyrrol-1-yl]pyridine;  3-(3-pyridin-2-yl-1H-pyrrol-1-yl)benzonitrile; 2-{1-[3-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl}pyridine;  2-[1-(3,5-dichlorophenyl)-1H-pyrrol-3-yl]pyridine; 2-[1-(3-methylphenyl)-1H-pyrrol-3-yl]pyridine;  2-[1-(3-methoxyphenyl)-1H-pyrrol-3-yl]pyridine;  3-[3-(1,3-thiazol-2-yl)-1H-pyrrol-1-yl]benzonitrile;  3-fluoro-5-(3-pyridin-2-yl-1H-pyrrol-1-yl)benzonitrile;  3-(3-bromo-4-pyridin-2-yl-1H-pyrrol-1-yl)-5-fluorobenzonitrile;  3-fluoro-5-(3-methyl-4-pyridin-2-yl-1H-pyrrol-1-yl)benzonitrile;  3-(3-chloro-4-pyridin-2-yl-1H-pyrrol-1-yl)-5-fluorobenzonitrile;  3-fluoro-5-[3-(1H-pyrazol-1-yl)-1H-pyrrol-1-yl]benzonitrile;  2-chloro-6-(3-pyridin-2-yl-1H-pyrrol-1-yl)pyridine;  2-(pyridin-3-yloxy)-6-(3-pyridin-2-yl-1H-pyrrol-1-yl)pyridine;  2-chloro-4-methyl-6-(3-pyridin-2-yl-1H-pyrrol-1-yl)pyridine;  3-chloro-5-(3-pyridin-2-yl-1H-pyrrol-1-yl)benzonitrile; 2-{1-[3-fluoro-5-(pyridin-3-yloxy)phenyl]-1H-pyrrol-3-yl} pyridine;  3-bromo-5-(3-pyridin-2-yl-1H-pyrrol-1-yl)benzonitrile;  3-methyl-5-(3-pyridin-2-yl-1H-pyrrol-1-yl)benzonitrile;  3-fluoro-5-[3-(1,3-thiazol-2-yl)-1H-pyrrol-1-yl]benzonitrile; and pharmaceutically acceptable salts thereof, are characterized by being substituted directly with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, and are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorder and panic, as well as in the treatment of pain, circadian rhythm disorders, and other diseases.
Patent CA-2473623-A1 (CA)
Title: Covered endoprosthesis and delivery system
Inventor: CULLY EDWARD H
IPC: A61F2/844
Filed: 2000-01-21
Abstract: The present invention is an improved endovascular device particularly useful for use in transjugular intrahepatic portosystemic shunt (TIPS) procedures. The device employs a two-part stent-graft construction that provides a low permeability membrane to line the shunt and an uncovered stent portion designed to reside in the portal vein. The device provides numerous benefits over previous stems and stent-grafts used in TIPS procedures, including being more compact to deliver, being easier to accurately deploy, a controlled compacted surface with tucked apices, an improved stent winding pattern, and being more flexible in delivery and use.
Patent CA-2477762-A1 (CA)
Title: Peptides for use in antitumor immunotherapy
Inventor: BENLALAM HOUSSEM
IPC: C12N15/09
Filed: 2003-03-04
Abstract: The invention concerns the use of immunogenic peptides representing T epitopes presented by the MHC I, derived from Melan-A, MAGE-A6, gp 100, tyrosinase and NY-ESO-1 antigens for the diagnosis or treatment of melanomas in HLA-B35 subjects.
Patent CA-2478519-A1 (CA)
Title: Process for loading and thermodynamically activating drugs on polymers by means of supercritical fluids
Inventor: BRESCIANI MASSIMO
IPC: A61K9/14
Filed: 2003-03-07
Abstract: The present invention refers to a process of loading drugs in a thermodynamic activated form into polymers by means of supercritical fluids. The process includes a pre-treatment step of the cross-linked polymer with pure supercritical fluid to allow a higher degree and a more rapid kinetic of drug loading into cross-linked polymers and also a higher thermodynamic activation of the drugs.
Patent CA-2478570-A1 (CA)
Title: Appareil et systeme de traitement de donnees, procede de commande de l'acces memoire
Inventor: LE THINH M
IPC: G06F13/16
Filed: 2002-03-04
Abstract: Dans la présente invention, un processeur de données comprend une mémoire pourvue d'éléments de stockage disposés en colonnes et un certain nombre de décodeurs de colonnes lesquels disposent chacun d'un port d'accès mémoire. Le processeur de données comprend une pluralité d'éléments de traitement et chacun des ports de mémoire peut être respectivement couplé à au moins un des éléments du processeur, de sorte que chaque élément de processeur peut accéder à au moins une colonne d'éléments de stockage.
Patent CA-2480110-A1 (CA)
Title: Indicator attachment mechanism and method and apparatus for removing indicators from hangers
Inventor: GOULDSON STANLEY F
IPC: B65C7/00
Filed: 1996-02-02
Abstract: A molded plastic garment hanger having an improved indicator attachment device is disclosed, wherein the hanger has a hook with an upstanding web to be received within a downwardly opening cavity of a molded plastic indicator having side walls formed with openings. The web is formed with attachment means in the form of a resilient plastic detent formed with a laterally projecting portion positioned to engage the opening to prevent removal of the indicator from the hook unless the resilient detent is physically displaced from the opening to facilitate release of indicator from the hook. A method and apparatus for removing the indicator from the hook is also provided by inserting a pin defined on a first plate into the indicator to displace the indicator attachment mechanism and thereby release the indicator from the indicator attachment mechanism without damaging either the indicator or the indicator attachment mechanism. The present invention contemplates automated as well as manual removal of the indicator from the hook of a hanger and provides a method and device therefor.
Patent CA-2480138-A1 (CA)
Inventor: LEVINSON R SAUL
IPC: A61P19/10
Filed: 2003-03-21
Abstract: This invention relates to a novel transcellular drug delivery system suitable for controlled delivery of a therapeutically active material across various membranes. The transcellular drug delivery system has a bioadhesive unilamellar vesicle defining an amphiphilic exterior and an aqueous interior, wherein a therapeutically active ingredient is contained inside the aqueous interior.
Patent CA-2480411-A1 (CA)
Title: Composite sol, process for producing the same, and ink-jet recording medium
Inventor: KATO HIROKAZU
IPC: B82Y10/00
Filed: 2003-03-25
Abstract: A composite sol containing colloidal composite particles which have a partic le diameter as measured by the dynamic light scattering method of 20 to 500 nm and comprise colloidal silica particles having a diameter as determined from the specific surface area of 3 to 100 nm and aluminum phosphate with which t he colloidal silica particles are bonded to one another or are coated and bonde d to one another; a coating composition for ink-receiving layer formation whic h comprises the composite sol; and an ink-jet recording medium having an ink- receiving layer comprising the composite sol.
Patent CA-2481722-A1 (CA)
Inventor: KAVANAGH BROCK R
IPC: E04B9/10
Filed: 2003-03-27
Abstract: A connector for a main tee of a suspended ceiling grid that has improved sel f- aligning and connection force properties. The connector has an end tab (21) with a forward portion bent at a lead angle and a receiving pocket (22) with an outwardly flared entrance that, with an opposed identical connector, cooperate to provide smooth horizontal alignment. The end portion, additionally, includes an edge profile that vertically aligns itself with th e receiving pocket (22) of the opposed connector. The receiving pocket (22) includes a spring-like resilient wall that limits the assembly force to overcome interference with projecting lock lances even when the connectors a re nearly out of dimensional tolerance. The spring-like pocket wall, shape of t he lock lance, and reinforcing beads contribute to an improved audible click signaling that a connection has been completed. The lock lance works with a relief groove to augment self-alignment of the connectors.
Patent CA-2482310-A1 (CA)
Inventor: BARON STEPHANE
IPC: A61H33/00
Filed: 2004-09-22
Abstract: An electromagnetic treatment system and method of use in combination with a bathtub or shower enclosure and preferably, but not exclusively, a therapeutic type enclosure provided with a therapeutic device to subject a user person to a therapeutic treatment, as well as an electromagnetic treatment. The electromagnetic treatment system comprises an electromagnetic coil attached to an outside surface of the wall of the therapeutic enclosure and surrounds a space in the enclosure where a user person is disposed to undergo an electromagnetic treatment. A pulsating voltage generator is connected to the electromagnetic coil for generating a pulsating electromagnetic about the coil. The electromagnetic field is oriented relative to the space. A control circuit controls the generator and a remote control, which is secured to the therapeutic enclosure and accessible to a user person, actuates the generator through the control circuit.
Patent CA-2487994-A1 (CA)
Title: Hydraulic cement based on calcium phosphate for surgical use
Inventor: BOHNER MARC
IPC: A61L27/12
Filed: 2003-05-13
Abstract: The hydraulic cement is based on calcium phosphate for surgical use. It comprises a first component comprising .alpha.-tricalcium phosphate powder particles, a second component comprising calcium sulphate dihydrate, and a third component comprising water. Furthermore the hydraulic cement does not contain more calcium sulfate hemihydrate (CSH) than 10 % of the total amount of said calcium sulphate dihydrate (CSD). This cement has the advantage that it has not a very basic component such as TTCP, consists of a limited amount of components, sets fast, and is easy to mix.