baber/WOPTO huggingface dataset:
Patent DE-69524448-D1 (DE)
Inventor: HOLLAND JOHN W
IPC: B01J13/02
Filed: 1995-10-02
Granted: 2002-01-17
Abstract: The present invention provides a fusogenic liposome comprising a lipid capable of adopting a non-lamellar phase, yet capable of assuming a bilayer structure in the presence of a bilayer stabilizing component; and a bilayer stabilizing component reversibly associated with the lipid to stabilize the lipid in a bilayer structure. Such fusogenic liposomes are extremely advantageous because the rate at which they become fusogenic can be not only predetermined, but varied as required over a time scale ranging from minutes to days. Control of liposome fusion can be achieved by modulating the chemical stability and/or exchangeability of the bilayer stabilizing component(s). The fusogenic liposomes of the present invention can be used to deliver drugs, peptide, proteins, RNA, DNA or other bioactive molecules to the target cells of interest.
Patent DE-69525375-D1 (DE)
Inventor: JANACEK JAROSLAV
IPC: A61M29/02
Filed: 1995-12-29
Granted: 2002-03-21
Abstract: A dilation catheter for use in performing angioplasty procedures. The catheter includes a relatively long catheter shaft which has two lumens. A relatively short guidewire receiving tube is thermally bonded to the distal end of the shaft, with its lumen approximately aligned with one of the lumens of the catheter shaft and a stiffening wire positioned therein. A dilation balloon, preformed with a shape that enables it to be used in an offset configuration, is thermally bonded to the distal and proximal ends of the tube, with its lumen aligned with the remaining lumen of the catheter shaft. The balloon and tube together define channels for the perfusion of blood past the balloon, which channels remain open even when the balloon bears against the tube during the inflation thereof.
Patent DE-69527732-D1 (DE)
Inventor: KUUSENTO JAAKKO
IPC: B25D17/06
Filed: 1995-05-23
Granted: 2002-09-12
Abstract: PCT No. PCT/FI95/00280 Sec. 371 Date Nov. 24, 1997 Sec. 102(e) Date Nov. 24, 1997 PCT Filed May 23, 1995 PCT Pub. No. WO96/37345 PCT Pub. Date Nov. 28, 1996A percussion piston for use in a drilling apparatus includes a drill bit and at least three tubular parts which increase in diameter in a direction extending from the drill bit toward a rear end of the piston. The piston further includes flanges positioned between the tubular parts and a first corresponding delivery space at the rear end of the piston. At least two additional corresponding delivery spaces are positioned between the first corresponding delivery space and the drill bit. Channels allow the transport of pressurized hydraulic fluid to and from the first and additional corresponding delivery spaces such that an energy pulse produced by impact of the piston on the drill bit is almost completely absorbed by the drilled object.
Patent DE-69535024-D1 (DE)
Inventor: COHEN-HAGUENAUER ODILE
IPC: C12N7/04
Filed: 1995-11-30
Granted: 2006-07-06
Abstract: The present invention relates to novel cell lines, so-called transcomplementation cell lines, which enable the packaging of recombinant retroviral RNAs carrying nucleotide sequences of interest. The present invention aims at transferring and expressing these sequences in eucaryotic target cells. The invention also related to expression vectors for the transcomplementation of defective retroviral vectors.
Patent DE-69535680-D1 (DE)
Inventor: BURKE RAE LYN
IPC: C12Q1/70
Filed: 1995-07-21
Granted: 2008-02-21
Abstract: The present invention relates generally to modified secreted viral proteins, to the genes which express these proteins and to antibodies produced against such proteins, and to the use of these materials in diagnostic and vaccine applications. In particular, the present invention describes deletion of the transmembrane region only and retention of at least part of the cytoplasmic domain itself or fusion with at least part of an alternate cytoplasmic domain. The result will generally be the secretion of proteins which are normally membrane-bound (nonsecretory). This invention greatly increases the efficiency of secretion of the derivative protein. Specific viral proteins of interest include, but are not limited to, those from CMV, HSV, EBV, VZV, HCV, HIV, and influenza.
Patent DE-69605322-D1 (DE)
Inventor: PEIPER URI
IPC: A61L2/20
Filed: 1996-08-27
Granted: 1999-12-30
Abstract: PCT No. PCT/IL96/00090 Sec. 371 Date Apr. 23, 1998 Sec. 102(e) Date Apr. 23, 1998 PCT Filed Aug. 27, 1996 PCT Pub. No. WO97/09071 PCT Pub. Date Mar. 13, 1997The present invention provides a method for sterilization of objects including the steps of placing the object that should be sterilized in a closed vessel; placing the closed vessel between two high voltage electrodes; applying a high voltage between the electrodes and converting the oxygen in the air inside the closed vessel into ozone; and keeping the sterilized object inside the closed vessel as long as needed. A "closed vessel" includes also any form of closed container or any closed plastic bag. The closed vessel may or may not have internal electric conductors. Furthermore, the invention provides a device for ozone sterilization of objects for use in the method. The device for sterilization comprises a sterilization chamber; two parallel high voltage electrodes located inside the chamber and connected to a high voltage transformer; a closed vessel with or without internal electrodes located between the two high voltage electrodes and the object to be sterilized is placed inside the vessel; and two parallel insulators located between the two high voltage electrodes and the closed vessel.
Patent DE-69606391-D1 (DE)
Inventor: CHISHOLM THOMAS
IPC: H01L21/027
Filed: 1996-12-11
Granted: 2000-03-02
Abstract: PCT No. PCT/EP96/05528 Sec. 371 Date Aug. 29, 1997 Sec. 102(e) Date Aug. 29, 1997 PCT Filed Dec. 11, 1996 PCT Pub. No. WO97/25735 PCT Pub. Date Jul. 17, 1997An electron beam pattern-writing column comprises an emitter and an extractor (14, 15) for generating a low-energy electron beam (13), a series of three electrostatic triple element lenses (17, 18, 21) for focussing the beam, and an electrostatic double deflector (20), which is disposed ahead of the final lens (21), for deflecting the beam to scan a substrate (11) on which a pattern is to be written. After focussing and deflection of the beam have been carried out by the electrostatic components, which are low power and thus have no significant heat output, the beam electrons are accelerated by the final element (21c) of the final lens (21) into a high-energy beam with the required strength for high-quality pattern writing.
Patent DE-69610614-D1 (DE)
Inventor: TROKHAN DENNIS
IPC: D21F11/00
Filed: 1996-01-24
Granted: 2000-11-16
Abstract: The invention comprises a method for applying a curable resin, such as a photosensitive resin, to a substrate such as a papermaker's dewatering felt. The method comprises the steps of providing a substrate; providing a curable liquid resin; providing a second material different from the curable liquid resin; applying the second material to the substrate to occupy at least some of the voids in the substrate intermediate the first and second surfaces of the substrate; applying the curable resin to the substrate; curing at least some of the resin to provide a resin layer on the substrate; and removing at least some of the second material from the substrate, wherein at least some of the second material is removed from the substrate after applying the curable resin to the substrate.
Patent DE-69611403-D1 (DE)
Inventor: ITO LARRY N
IPC: C07C17/358
Filed: 1996-07-04
Granted: 2001-02-08
Abstract: Allylic geminal dihalogen compounds such as 3,3-Dichloropropene coming, for example, as an intermediate boiling byproduct stream from a process of making allyl chloride by the chlorination of propylene, are converted into 1,3-dihalo allylic compounds such as cis- or trans-1,3-dichloropropene or a mixture of these by contact in the liquid phase with an alumina, silica or zeolite catalyst possessing a predominance of basic sites and a particle size of 0.15 mm to 12.5 mm and /or an alkali or alkaline earth content of 0.1 to 10 weight percent.
Patent DE-69614850-D1 (DE)
Inventor: RYBERG MOUSINHO DE FIGUEIREDO
IPC: G07F7/00
Filed: 1996-05-02
Granted: 2001-10-04
Abstract: A testing apparatus which is arranged to execute selectively commandable preprogrammed operations comprises a credit memory (12) for storing a credit balance and input means (14, 16) for inputting a credit code defining a predetermined credit sum into the apparatus which is arranged, upon an input of a credit code, to check the validity of said code (block 31) and, if the code is found to be valid, to increase the stored credit balance by the sum corresponding to said code (block 34), the apparatus being further arranged, upon a command for an operation subject to a charge, to check whether the stored credit balance amounts at least to a sum corresponding to the stipulated charge for said operation and to permit an execution of said operation only if this is the case (block 22) and to decrease the stored credit balance by said sum (block 26) in connection with the execution of said operation (block 25).
Patent DE-69619667-D1 (DE)
Inventor: HAKANSSON LEIF
IPC: G01N33/48
Filed: 1996-05-10
Granted: 2002-04-11
Abstract: The present invention relates to a method of predicting the therapeutic response of a drug directed towards a cancer in a human patient using samples of blood cells taken from the patient at different times. The method comprises the steps of culturing cells from the samples in a suitable medium; adding a stimulator of proliferation and an immuno-modulating drug of the cells to the culture; and assaying the proliferation of the cells in the culture; comparing the assay of proliferation with a previously made analysis demonstrating correlation between the proliferation of the cells and parameters of the therapeutic response of the drug in the human patient.
Patent DE-69621532-D1 (DE)
Inventor: BARON LIONEL
IPC: A61B17/15
Filed: 1996-08-21
Granted: 2002-07-11
Abstract: The apparatus has a gantry frame (1) and two pairs of runners (21, 22; 31, 32) over and parallel to each other. They form trailing sections (21B, 22B; 31B, 32B) at the leading side of the frame, and leading sections (21A, 22A; 31A, 32A) on a plane at right angles to the frame. The leading and trailing sections of the lower pair (2) of runners are firmly fixed, and slide together in relation to the frame. The leading and trailing sections of the upper pair of runners (3) are not bonded, so that the leading sections (31A, 32A) of the upper pair can slide separately. The rear sections of the upper pair are both bonded to the frame.
Patent DE-69622382-D1 (DE)
Inventor: CORBETT EDMUND
IPC: B66C1/42
Filed: 1996-03-21
Granted: 2002-08-22
Abstract: PCT No. PCT/AU96/00152 Sec. 371 Date Sep. 19, 1997 Sec. 102(e) Date Sep. 19, 1997 PCT Filed Mar. 21, 1996 PCT Pub. No. WO96/29273 PCT Pub. Date Sep. 26, 1996A lifting device suited for use in lifting and handling heavy slabs, sheets of material, or panels generally includes a frame comprising side-plates, the upper ends of which are rigidly secured together by cross-members. The lower portion of one side-plate is angled downwardly and away from the other side-plate. A carriage is arranged between the lower portion of the one side-plate and a movable jaw for vertical movement with respect to the frame. The movable jaw is mounted for horizontal sliding movement on the cross-members between the side-plates. The carriage is suspended from a tension-member, which is guided for vertical movement by the cross-members and has its upper end secured to (or formed as) a lifting lug. When the lifting device is placed over, for example, a slab to be lifted, the carriage is raised by lifting the tension-member, and the slab is clamped sufficiently tightly to be lifted.
Patent DE-69622990-D1 (DE)
Inventor: KANKAANPAEAE-ANTTILA BARBARA
IPC: A21D2/00
Filed: 1996-01-19
Granted: 2002-09-19
Abstract: PCT No. PCT/FI96/00042 Sec. 371 Date Jul. 18, 1997 Sec. 102(e) Date Jul. 18, 1997 PCT Filed Jan. 19, 1996 PCT Pub. No. WO96/22027 PCT Pub. Date Jul. 25, 1996The invention relates to a process for producing a product containing flax proteins and flax mucilage, in which process linseeds are cold and/or hot pressed and, if desired, further extracted with a suitable solvent for separating the linseed oil, the resulting pressed and crushed flax is alkali extracted and the insoluble fibre is separated, the alkaline extract is precipitated with an acid and a lower alkanol for producing a precipitate containing proteins and mucilage, the lower alkanol is separated from the precipitate and the resulting preparation is used as such or it is dried and possibly mixed with suitable adjuvants. The invention also relates to a flax protein product containing flax mucilage and its use in food processing, especially in baking.
Patent DE-69633374-D1 (DE)
Inventor: ANDRUS WINFIELD SCOTT
IPC: A61B17/00
Filed: 1996-11-11
Granted: 2004-10-21
Abstract: An apparatus and method for the treatment of diseases of the prostate, including BPH and prostate cancer, utilizing transurethrally applied focussed ultrasound energy to produce hyperthermal and thermotherapeutic effects in diseased tissue are disclosed. A first preferred embodiment of the apparatus relies on visual control; and a second preferred embodiment of the apparatus incorporates an integrated ultrasonic imaging and therapy transducer. The apparatus and method feature the close proximal placement of the ultrasound transducer to the diseased tissue to be treated, resulting in less attenuation of the beam and deposition of a greater fraction of the total emitted ultrasound energy in the selected portion of the diseased tissue. The ultrasound energy passes atraumatically through the urethral wall and other tissue not targeted. At the focal point of the ultrasound energy, substantial heating of diseased tissue to produce hyperthermal effects therein occurs, and even higher thermotherapeutic temperatures are attainable to produce coagulative necrosis of diseased tissue. <IMAGE>
Patent DE-69634357-D1 (DE)
Inventor: BRENNER S
IPC: A61K31/66
Filed: 1996-06-03
Granted: 2005-03-24
Abstract: PCT No. PCT/US96/08284 Sec. 371 Date Dec. 3, 1997 Sec. 102(e) Date Dec. 3, 1997 PCT Filed Jun. 3, 1996 PCT Pub. No. WO96/39149 PCT Pub. Date Dec. 12, 1996Disclosed is a method for treating and preventing bone loss in patients by administering a formulation of anhydrous alendronate sodium. Also described is a pharmaceutical dosage form of said anhydrous alendronate sodium, being anhydrous 4-amino-1-hydroxy-butylidene-1,1-bisphosphonic acid, monosodium salt, in a pharmaceutically acceptable excipient.
Patent DE-69637332-D1 (DE)
Inventor: WILLIAMS LEWIS T
IPC: C07H21/04
Filed: 1996-09-27
Granted: 2008-01-03
Abstract: The invention provides a therapeutical composition for epithelial wound repair that is a combination of PDGF and KGF. Further, the invention provides a composition for epithelial wound repair that is a therapeutic combination of PDGF, KGF and IGF. Additionally, the invention provides a therapeutic composition of PDGF, KGF, IGF and IGFBP for epithelial wound repair
Patent DE-69637430-D1 (DE)
Inventor: DOOLEY COLETTE T
IPC: C07K5/10
Filed: 1996-06-03
Granted: 2008-03-27
Abstract: The present invention provides novel opioid peptides which are selective for the kappa opiate receptor. In one embodiment, the kappa-selective opioid peptides have the general structure (D)Phe-D4-E5-F6 (SEQ ID NO. 29), wherein D4 is (D)NapAla or (D)Phe, E5 is (D)Nle, Trp, or (D)Ile, and F6 is (D)Arg or (D)ChAla.
Patent DE-69702666-D1 (DE)
Inventor: BENOIT JEAN-PIERRE
IPC: B01J13/02
Filed: 1997-09-24
Granted: 2000-08-31
Abstract: The invention concerns a method for preparing microcapsules containing an active substance coated with a substantially polar polymer film, characterized in that it consists in the following steps: suspending an active substance insoluble in a substantially polar polymer solution in an organic solvent, said substantially polar polymer being insoluble in liquid or supercritical CO2, said organic solvent being soluble in liquid or supercritical CO2; contacting the suspension with liquid or supercritical CO2 so as to extract the solvent from the polymer in a controlled manner and ensure the coacervation of the polymer; substantially extracting the solvent by means of supercritical CO2 and draining off the CO2/solvent mixture; recuperating the microcapsules in the form of dry powder. The invention also concerns microcapsules containing an active substance coated with a substantially polar polymer selected among the group consisting of polysaccharides, cellulose derivatives, acrylic, methacrylic polymers or derivatives of esters of vinyl, polyesters, polyamides, polyanhydrides, polyorthoesters and polyphosphazenes, characterized in that the polymer film has low surface energy and is free from organic solvent and in that the microcapsules are obtainable by said method.
Patent DE-69704146-D1 (DE)
Inventor: COLOMBO EZIO
IPC: B65G57/18
Filed: 1997-10-08
Granted: 2001-04-05
Abstract: A rotary electromagnetic head for automatic stackers of iron sections originating from a rolling mill comprises an expulsion device provided with a bar (13) rotating together with the head (10) but also provided with simultaneous movement relative to the head (10). Said relative movement is caused by a cam (15) against the action of a counteracting spring (20). <IMAGE>
Patent DE-69710614-D1 (DE)
Inventor: HOMYONFER MOSHE
IPC: G02F1/1524
Filed: 1997-11-27
Granted: 2002-03-28
Abstract: A method for the preparation of nanoparticles of metal oxides containing inserted metal particles and to metal-intercalated and/or metal-encaged "inorganic fullerene-like" (hereinafter IF) structures of metal chalcogenides obtained therefrom is provided, which comprises heating a metal I material with water vapor or electron beam evaporation of said metal I material with water or another suitable solvent, in the presence of a metal II salt, and recovering the metal II-doped metal I oxide, or proceeding to subsequent sulfidization, yielding bulk quantities of metal II-intercalated or metal II-encaged IF structures of the metal I chalcogenide. The metal II salt is preferably an alkaline, alkaline earth or transition metal salt, most preferably an alkali chloride. The intercalated and/or encaged IF structures are usable as lubricants. They also form stable suspensions, e.g. in alcohol, and electrophoretic deposition from said suspensions yields thin films of the intercalated IF materials, which have a range of potential applications.
Patent DE-69713898-D1 (DE)
Inventor: SLARK TREVITHICK
IPC: C08F8/14
Filed: 1997-12-17
Granted: 2002-08-14
Abstract: The present invention describes a process for the making of a copolymer of the general formula (I)wherein A is a residue of at least one (meth)acrylate monomeric species, B is a residue of at least one monomeric species copolymerizable with A, R is a (meth)acrylate functionalized pendant ester group, X1 and X2 are terminal groups which may be the same or different, n and p are both at least one and are chosen such that the copolymer has a number average molecular weight of more than 2000.
Patent DE-69715590-D1 (DE)
Inventor: EKBLOM KARL
IPC: B65B25/14
Filed: 1997-05-28
Granted: 2002-10-24
Abstract: A method and apparatus for wrapping cardboard and paper rolls for protection during shipping and handling. The rolls are wrapped in a strip of wrapping material, that has a width which does not exceed the length of the roll. The roll is transferred to the wrapping station on a transporter and is stopped using a mechanical positive stop so that a edge of the cylindrical part of the roll is aligned with a first edge of the wrapper roll mounted in the wrapping station. When the roll is stopped, a first layer of the wrapper is wound on the roll. Then, if the length of the roll is greater than the width of the wrapper, the relative position of the roll and the wrapper is changed so that the second edge of the cylindrical part of the roll is aligned with the second edge of the wrapper roll, and a second layer of wrap is wound on the roll.
Patent DE-69718907-D1 (DE)
Inventor: RYAN O
IPC: G06T3/00
Filed: 1997-05-29
Granted: 2003-03-13
Abstract: Fingerprinting and fingerprint detection techniques are described which, unlike typical fingerprint systems used to conceal video signals, are compatible with all conceivable forms of signal compression systems while still allowing viewing of the video signal. The fingerprint technique is based on the principle of applying very slight local spatial distortion to the pixels in a video image, and the like, by means of selected warp patterns. Thus the technique provides means for conveying, within the video signal, selected information in the form of the fingerprint which is detectable electronically but which is not noticeable to a critical viewer who is watching the video signal. That is, the resultant fingerprinted video signal will appear to be identical to the undistorted video signal. The fingerprint detection technique provides for the recovery of the conveyed information which may comprise an instruction to prevent the fingerprinted video image from being copied, messages which allow identifying the source and date of an unauthorized copy of the video image, etc.
Patent DE-69727202-D1 (DE)
Inventor: DUNN JAMES M
IPC: H04M3/56
Filed: 1997-11-04
Granted: 2004-02-19
Abstract: A conference server system, for internal use in the public switched telephone network (PSTN), links to public data communication networks (e.g. the Internet) for distributing computer displayable data between participants in voice telephone conferences. The server system includes a computer sub-system for storing data generated by the participants and distributing the data in coordination with voice presentations of respective participants. Data so stored and distributed includes computer-displayable data. Other data handled by the computer subsystem represents commands and functional requests issued by participants which pertain to the handling of computer-displayable data and voice parameters of the conference. conference participants, having separate and concurrent access to both the PSTN and the data network, receive and view computer-displayable data prepared by one of the participants in coordination with the respective voice conference. The conference server system connects to voice conference management resources of the PSTN in a manner enabling the server system to control voice parameters of a voice conference in response to data requests received from participants (e.g. requests from hearing-impaired participants for enhanced audio service), as well as enabling the conference management resources to control functions performed in respect to distribution of displayable data in response to spoken requests uttered by the participants, when the telephone system contains appropriate speech recognition equipment. <IMAGE>
Patent DE-69737751-D1 (DE)
Inventor: PENNER DONALD
IPC: A01H1/04
Filed: 1997-07-08
Granted: 2007-07-05
Abstract: Sugar beet plants which are resistant to imidazolinone herbicides are described. The sugar beet plants are derived from susceptible cells by selection for mutant imidazolinone resistant cells with the herbicide. The resistant plants derived from the cells can be grown in fields where imidazolinones have been used for weed control.
Patent DE-69803052-D1 (DE)
Inventor: MARKHAM ALEXANDER FRED
IPC: A61K35/76
Filed: 1998-02-24
Granted: 2002-01-31
Abstract: The invention relates to the use of anti-herpetic sensitive viruses in the treatment of diseases and particularly cancer. More specifically, the invention concerns the genetic manipulation of viruses that are susceptible to anti-herpetic agents so as to enhance their sensitivity to said agents and/or reduce their pathogenicity.