baber/WOPTO huggingface dataset:
Patent EP-3526799-A1 (EP)
Inventor: FROMMERT MONA
IPC: G16H30/40
Filed: 2018-01-08
Abstract: Disclosed is a computer-implemented method of determining an atlas element. The method encompasses acquiring model image data which describes at least one fixed element (an anatomical element such as an anatomical body part, for example a rib). Patient image data is acquired which describes an improvable element (an anatomical element such as an anatomical body part, for example heart). Next, region data is acquired, for example by assigning a homogeneous grey value to a region of the model image. The patient image is matched to the model image, wherein no matching is performed within the region. A transformation for mapping the improvable element into the region is determined based on matching. Several patient images are then mapped into the region and superimposed. An atlas element is determined based on the superimposed images. The method may be repeated using the determined anatomical atlas element as constraint to detect further atlas elements.
Patent EP-3574101-A1 (EP)
Inventor: LABS MATHIAS
IPC: C12N15/90
Filed: 2018-01-30
Abstract: La présente invention concerne des complexes moléculaires artificiels comprenant au moins une nucléase site-spécifique et un domaine d'accueil de modèle de réparation interagissant directement avec celle-ci au moins, ledit domaine d'accueil de modèle de réparation interagissant avec au moins une séquence d'acide nucléique de modèle de réparation. Le complexe artificiel peut en outre comprendre au moins un domaine d'interaction. Les complexes moléculaires artificiels sont conçus pour médier la réparation d'une séquence cible d'ADN dans un organisme procaryote ou eucaryote avec une précision élevée d'une manière ciblée et peuvent ainsi être utilisés pour l'ingénierie génomique dans une cellule ou un organisme procaryote ou eucaryote, ou pour l'édition d'un génome viral. L'invention concerne également des procédés de modification d'au moins une séquence cible d'ADN dans une cellule procaryote ou eucaryote ou un génome viral, par exemple, pour le développement de traits, ou pour le traitement d'une maladie. L'invention concerne en outre un procédé de fabrication d'une plante, d'une cellule végétale, d'un matériau végétal, ou d'un dérivé, ou d'une descendance de celle-ci comprenant au moins un complexe moléculaire artificiel ou édité par au moins un complexe moléculaire artificiel.
Patent EP-3580251-A1 (EP)
Title: Thermoplastisches polyurethan
Inventor: ROY NABARUN
IPC: C08G18/66
Filed: 2018-02-13
Abstract: Die vorliegende Erfindung betrifft thermoplastische Polyurethane erhältlich oder erhalten durch Umsetzung mindestens einer Polyisocyanatzusammensetzung, die 4,4'-MDI und mindestens ein weiteres Polyisocyanat enthält, mindestens eines Kettenverlängerers der allgemeinen Formel (I), und mindestens einer Polyolzusammensetzung. Weiter betrifft die vorliegende Erfindung ein Herstellungsverfahren für derartige thermoplastische Polyurethane sowie die Verwendung eines erfindungsgemäßen thermoplastischen Polyurethans oder eines thermoplastischen Polyurethans erhältlich oder erhalten nach einem erfindungsgemäßen Verfahren zur Herstellung von Extrusionsprodukten, Filmen und Formkörpern.
Patent EP-3752915-A1 (EP)
Title: System for live migration of virtual machines with assigned peripheral devices
Inventor: SEREBRIN BENJAMIN CHARLES
IPC: G06F9/48
Filed: 2018-02-14
Abstract: Hardware transactions or other techniques, such as custom PCIe handling devices, are used to atomically move pages from one host's memory to another host's memory. The hosts are connected by one or two non-transparent bridges (NTBs), which make each host's memory and devices available to the other, while allowing each host to reboot independently.
Patent EP-3586172-A1 (EP)
Title: Real-time correction of calibration constants of a bore-hole logging tool using a reference detector
Inventor: TEAGUE PHILIP
IPC: G01V5/12
Filed: 2018-02-22
Abstract: An x-ray based litho-density tool for measurement of formation surrounding a borehole is provided, the tool including at least an internal length comprising a sonde section, wherein said sonde section further comprises an x-ray source; at least one radiation measuring detector; at least one source monitoring detector; a plurality of sonde-dependent electronics; and a reference detector, wherein the reference detector is used to monitor the output of the x-ray source such that the reference detector's output effects corrections to the outputs of the detectors used to measure the density of the materials surrounding the borehole in order to correct for variations in the x-ray source output. Tool logic electronics, PSUs, and one or more detectors used to measure borehole standoff such that other detector responses may be compensated for tool standoff are also provided. Shielding, through-wiring, wear-pads that improve the efficacy and tool functionality are also described and claimed.
Patent EP-3600308-A1 (EP)
Inventor: CANAUD GUILLAUME
IPC: A61K31/4439
Filed: 2018-03-29
Abstract: The invention relates to a method for treating mitochondrial genetic diseases. The inventors have worked with primary fibroblasts from patients and control individuals and collected protein lysates for western blotting. Importantly, they observed that the genetic mitochondrial disorders, show a significant increase in phosphorylation of ribosomal protein S6 (pS6) compared to control fibroblasts, indicative of hyperactivated mTOR signaling. Patients with mitochondrial disorders and controls cells were treated for 48 hours with DMSO or BYL719. All lines from patients with mitochondrial diseases show reduced membrane potential, determined by TMRE staining intensity, and abnormal morphology, fragmentation and the presence of depolarized (low TMRE staining) mitochondria. Treatment with BYL719 attenuated these phenotypes in all MELAS fibroblasts while having no overt impact on the control cells. Similar experiments using flow cytometry confirmed membrane potential (TMRE) rescue by BYL719 treatment in MELAS fibroblasts.
Patent EP-3612320-A1 (EP)
Title: Druckreinigungsvorrichtung, verfahren zum betreiben einer druckreinigungsvorrichtung und verfahren zum erkennen eines schlauchvorsatzes
Inventor: RUTTKAY TIBOR LEVENTE
IPC: F04B17/03
Filed: 2018-04-12
Abstract: Bei einer Druckreinigungsvorrichtung (100) mit einer Druckerzeugungseinheit (120) zur Druckbeaufschlagung eines Fluids und zur Abgabe eines druckbeaufschlagten Fluids über einen Schlauchvorsatz (150), bevorzugt über eine Handpistole oder über eine Reinigungsspritze,wobei die Druckreinigungsvorrichtung (100) in mindestens zwei unterschiedlichen Betriebsmodi betreibbar ist,sind der Druckerzeugungseinheit (120) ein bevorzugt elektrischer Drucksensor (220) zur Ermittlung eines jeweils aktuellen Betriebsdrucks und/oder ein Durchflussmengensensor zur Ermittlung einer jeweils aktuellen Durchflussmenge sowie eine Steuervorrichtung (240) zugeordnet, wobei die Steuervorrichtung (240) dazu ausgebildet ist, die Druckererzeugungseinheit (120) insbesondere auf der Basis von einem jeweils eingestellten Betriebsmodus in Abhängigkeit von einem jeweils aktuellen ermittelten Betriebsdruck und/oder einer jeweils aktuellen ermittelten Durchflussmenge zu steuern.
Patent EP-3622080-A1 (EP)
Inventor: CHAYOT ROMAIN
IPC: C12P5/02
Filed: 2018-04-19
Abstract: Described are methods for the production of isobutene wherein the enzymatic conversion of 3-methylcrotonic acid into isobutene is achieved by making use of an FMN-dependent decarboxylase associated with an FMN prenyl transferase, wherein said FMN prenyl transferase catalyzes the prenylation of a flavin cofactor (FMN or FAD) utilizing dimethylallyl phosphate (DMAP) into a flavin-derived cofactor, wherein said method further comprises providing said DMAP enzymatically. Moreover, described are methods for the production of isobutene wherein the enzymatic conversion of 3-methylcrotonic acid into isobutene is achieved by making use of an FMN-dependent decarboxylase associated with an FMN prenyl transferase, wherein said FMN prenyl transferase catalyzes the prenylation of a flavin cofactor (FMN or FAD) utilizing dimethylallyl pyrophosphate (DMAPP), wherein said method further comprises providing said DMAPP enzymatically.
Patent EP-3615931-A1 (EP)
Inventor: WEINSTOCK MARK
IPC: A61B5/15
Filed: 2018-04-25
Abstract: L'invention concerne un corps de séparation (100) servant à séparer une première d'une deuxième phase d'un liquide dans un contenant (200) de forme tubulaire. Le corps de séparation comporte un corps flottant (110) élastique pourvu d'un bord étanche (112) périphérique en forme de cercle vu d'en haut, destiné à venir en appui de manière étanche sur le côté intérieur du contenant de forme tubulaire dans une position étanchéifiée. Un corps de ballast (120) est fixé sur le côté inférieur du corps flottant. La densité du corps de ballast est plus importante que la densité du corps flottant, et la densité de l'ensemble du corps de séparation se situe dans une plage de valeurs comprise entre la densité de la première phase et la densité de la deuxième phase du liquide. Le corps flottant comporte un rétrécissement (114) local et, dans la zone du rétrécissement, une membrane (116).
Patent EP-3609386-A1 (EP)
Inventor: CANNELLA FERDINANDO
IPC: A61B5/00
Filed: 2018-04-12
Abstract: Device for detection of the tactile sensitivity of a user, comprising a base frame (1) and a mechanical system (2) attached to said base frame (1), which mechanical system (2) is movable relatively to said base frame (1 ) and which mechanical system (2) has a resting area (3) for the fingertip of at least one finger of said user. The mechanical system (2) comprises a plurality of movable plate-shaped members (21) arranged side by side to each other in such a way that said resting area (3) is defined by the thicknesses of at least part of the upper edges (211) of said plate-shaped members (21). Each plate-shaped member (21) is connected to an actuator (23) which can be operated to independently move each plate-shaped member (21) from a minimum height position to a maximum height position, a control unit being further provided which is adapted to operate said actuators (23).
Patent EP-3606559-A1 (EP)
Inventor: MEJIA ONETO JOSE MANUEL
IPC: C07H5/04
Filed: 2018-04-06
Abstract: Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of agents at the location of the tetrazine-containing biomaterial in a subject. The compositions and methods have applications in the treatment of various diseases or conditions including cancer, tumor growths, and bacterial infections.
Patent EP-3621837-A1 (EP)
Inventor: VEENEMAN JAN PETER
IPC: F16B2/22
Filed: 2018-05-11
Abstract: Mobile accommodation, comprising a wall (10) with a wall opening (20) bounded by an edge. Received in the wall opening is a casing frame (30) which is intended and configured to comprise an openable or non-openable panel (25). The casing frame extends outside the wall opening on a first side of the wall while it is fixed in the wall opening by means of fixation means. The casing frame comprises for this purpose an insertion cavity (35) accessible from an opposite side of the wall. The fixation means comprise at least one fastening clip (60) which at a first outer end comprises an insertion member (65) which protrudes into the insertion cavity (35) in order to effect a durable mutual connection therein, and at a second outer end supports directly or indirectly on the wall.
Patent EP-3642687-A1 (EP)
Inventor: PETRZIK LENARD
IPC: G05G5/06
Filed: 2018-05-23
Abstract: The invention relates to a rotary control device (1) for a vehicle comprising a user interface surface (3), in particular a knob, that is embodied to rotate with respect to a housing (5) of the device (1) around a rotational axis (7) of the device (1), further comprising a sensor unit (9) for monitoring the orientation and/or rotational movement of the user interface surface (3) with respect to the housing (5), a processing unit (11), and a communications interface (13) for transmitting control signals (Ts) according to an output (Op) from the processing unit (11), said output (Op) being generated by the processing unit (11) on the basis of sensor data (Ds) from the sensor unit (9).
Patent EP-3614998-A1 (EP)
Inventor: CHANG DEBORA W
IPC: A61Q5/02
Filed: 2018-04-25
Abstract: A hair care composition comprising from about 10% to about 25% of one or more surfactants; from about 0.01% to 10% of one or more surfactant soluble antidandruff agents; from about 0.1% to 10% of one or more anionic polymers from about 0.01% to 5% of one or more cationic polymers; wherein the composition has a deposition efficiency of greater than 1.2X that of a control composition wherein the control composition comprises 14% SLE1S, no polymeric constituents, 1% of the surfactant soluble antidandruff agent at a pH of about 6.
Patent EP-3479042-A1 (EP)
Title: Unité d'échange de chaleur pour dispositifs à pompe à chaleur, plus précisément un évaporateur de production et de stockage de glace
Inventor: MILA MIROSLAW
IPC: F28D1/04
Filed: 2018-04-16
Abstract: L'invention concerne une unité comprenant deux échangeurs de chaleur similaires (2.1, 2.2) compris dans le circuit d'agent thermodynamique par l'intermédiaire de collecteurs d'entrée (7.1, 7.2) et de collecteurs de sortie (8.1, 8.2). Les collecteurs d'entrée (7.1, 7.2) sont reliés aux collecteurs de sortie (8.1, 8.2) au moyen de canaux d'écoulement tubulaires perpendiculaires (5.1, 5.2). Les sections finales (10.1, 10.2) des raccords des canaux d'écoulement (5.1, 5.2) au collecteur de sortie (8.1, 8.2) sont courbées hors de la plaque du radiateur (4) commune aux deux échangeurs (2.1, 2.2), d'une dimension (e) supérieure à la moitié de la somme des diamètres extérieurs des collecteurs d'entrée (7.1, 7.2) et de sortie (8.1, 8.2). Des distributeurs à buse tubulaire, comportant de nombreux orifices de buse du côté dirigé de manière coaxiale vers les canaux d'écoulement (5.1, 5.2), sont introduits à l'intérieur des collecteurs d'entrée (7.1, 7.2). Les diamètres des orifices de buse augmentent successivement à partir de l'extrémité d'alimentation en agent thermodynamique. Les distributeurs à buse du premier (2.1) et du second (2.2) échangeur sont intégrés aux extrémités adjacentes des deux collecteurs d'entrée (7.1, 7.2). Les échangeurs de chaleur (2.1, 2.2) sont superposés afin d'alterner leurs sections longues droites des canaux d'écoulement (5.1, 5.2) dans le plan du radiateur (4) et sont reliés à une même plaque commune du radiateur (4).
Patent EP-3652033-A1 (EP)
Title: Method for operating a hybrid vehicle
Inventor: HORNBACHNER JOHANNES
IPC: B60W20/15
Filed: 2018-06-06
Abstract: The invention relates to a method for operating a hybrid vehicle, particularly a diesel hybrid vehicle, comprising an internal combustion engine (12) and an electric drive (14). According to the invention, a total power applied in order to drive the vehicle is divided according to a distribution ratio to the internal combustion engine (12) and the electric drive (14). At least in one transient mode of the internal combustion engine (12), dynamic parameters are used to determine an optimal load point of the internal combustion engine (12).
Patent EP-3639444-A1 (EP)
Title: Frequency offset estimation
Inventor: Ernström Per
IPC: H04L27/00
Filed: 2018-06-15
Abstract: P72243 WO1 34 ABSTRACT A radio node (14) is configured to perform frequency offset estimation. The radio node (14) in this regard receives a first set (22-1) of reference symbols of a reference signal during respective time resources, and determines a first frequency offset estimate (26-1) using the first set (22-1) of reference symbols. The radio node (14) also receives a second set (22-2) of 5 reference symbols of the reference signal during respective time resources, e.g., using the same local oscillator frequency for down conversion as with the first set (22-1). The radio node (14) further determines, based on the first frequency offset estimate (26-1), a second frequency offset estimate (26-2) using the second set (22-2) of reference symbols. In some embodiments, the radio node (14) determines a third frequency offset estimate as a sum of the first and 10 second frequency offset estimates, and tunes a local oscillator frequency, or performs frequency offset compensation, based on the third frequency offset estimate. [Fig. 2]
Patent EP-3638148-A1 (EP)
Inventor: SCHERER JOHANNES
IPC: A61C8/02
Filed: 2018-05-23
Abstract: Die Erfindung betrifft ein Dentalimplantatsystem umfassend wenigstens ein Zahnimplantat (1) sowie ein separates Abutment (2), welches an dem Zahnimplantat (1) durch eine Befestigungsschraube (3) befestigbar oder befestigt ist. Die Erfindung sieht vor, dass das Zahnimplantat (1) aus einem ersten Material besteht, welches einen Elastizitätsmodul zwischen 15 GPa und 75 GPa aufweist, und dass das Abutment (2) aus einem zweiten Material besteht, welches einen Elastizitätsmodul größer als 100 GPa aufweist, wobei die Befestigungsschraube (3) aus dem ersten Material oder aus dem zweiten Material besteht. Mit diesen Maßnahmen ist beim Gebrauch des Dentalimplantatsystems eine Reduzierung der Neigung zur Ausbildung einer Periimplantitis möglich.
Patent EP-3645544-A1 (EP)
Title: Multiple coupling&oxidation method
Inventor: FUNDER ERIK DAA
IPC: C07H19/06
Filed: 2018-06-26
Abstract: The present invention relates to the field of stereodefined phosphorothioate oligonucleotides and to stereodefining nucleoside monomers and methods of synthesis of stereodefined oligonucleotides using said monomer. Herein are disclosed oligonucleotide enhanced synthesis methods where within a single elongation cycle there are repeated coupling and oxidation steps. The method results in an enhanced yield and higher purity of stereodefined phosphorothioate oligonucleotides
Patent EP-3612189-A1 (EP)
Inventor: LEONOV GERMAN
IPC: A61K31/7088
Filed: 2018-05-31
Abstract: The disclosure relates to the assembly of Virus Like Particles [VLPs] using packaging native and artificial packaging signals and their use in vaccines and immunological compositions and the methods of vaccination or immunisation against human and animal viral pathogens.
Patent EP-3635051-A1 (EP)
Inventor: THUILLIEZ JULIEN
IPC: C08F210/02
Filed: 2018-06-06
Abstract: The present invention relates to an ethylene and 1,3-butadiene copolymer containing ethylene units, butadiene units and 1,2-cyclohexanediyl cyclic structural units, and bearing, at one of its chain ends, an alkoxysilyl or silanol function, the functional group F 1 .
Patent EP-3811359-A1 (EP)
Inventor: KRACUN ALEKSANDAR
IPC: G10L21/00
Filed: 2018-06-25
Abstract: A method (400) includes receiving text input data (302) for conversion into synthesized speech (160) and determining, using a hotword-aware model (320) trained to detect a presence of a hotword (130) assigned to a user device (110), whether a pronunciation of the text input data includes the hotword. The hotword is configured to initiate a wake-up process on the user device for processing the hotword and/or one or more other terms following the hotword in the audio input data. When the pronunciation of the text input data includes the hotword, the method also includes generating an audio output signal (304) from the text input data and providing the audio output signal to an audio output device (118) to output the audio output signal. The audio output signal when captured by an audio capture device of the user device, configured to prevent initiation of the wake-up process on the user device.
Patent EP-3582325-A1 (EP)
Inventor: HAYASHI KENJI
IPC: H01Q23/00
Filed: 2018-02-08
Abstract: A planar antenna includes a multilayer ceramic body10having an upper surface and a lower surface, and including a plurality of ceramic layers stacked together, at least one radiation conductor31positioned at one of interfaces between the plurality of ceramic layers in the multilayer ceramic body or on the upper surface of the multilayer ceramic body, a ground conductor32positioned at another one of the interfaces between the plurality of ceramic layers in the multilayer ceramic body or on the lower surface of the multilayer ceramic body, and a low-dielectric-constant region115positioned in the multilayer ceramic body between the radiation conductor and the ground conductor, and having a plurality of hollow portions.
Patent EP-3638075-A1 (EP)
Inventor: GIOVANNINETTI STEFANO
IPC: A47B13/02
Filed: 2018-06-15
Abstract: The frame comprises a first part (2) resting on a plane and a second part (3) interlockingly fastened to the first part (2). The first part (2) comprises four vertical uprights (4a and 4b) and a plurality of internally hollow bodies defined by a sleeve with a vertical axis (5, 6, 7 and 8) housing a portion of the respective vertical upright (4a and 4b) and by a sleeve with a horizontal axis (5a, 6a, 7a and 8a) housing the axial end of a respective horizontal bar (13, 15 and 17). The sleeves with a vertical axis (5, 6, 7 and 8) are freely rotatable about the axis of the respective upright (4a and 4b) so that the first part (2) can take a configuration with reduced overall dimensions and a prismatic shaped configuration on which the second part (3) is arranged. The first part (2) defines an inner space housing a first instrument (9), the second part (3) supports a second instrument (10) and the faces of the first part (2) are shaped so as to allow the hooking and the arrangement of members and the passage of assembling means between the inner and outer instruments of the first part (2) and supported by the second part (3).
Patent EP-3682042-A1 (EP)
Title: Method for pretreating aluminum materials, particularly aluminum wheels
Inventor: SEBRALLA LARS
IPC: C09D133/02
Filed: 2018-09-11
Abstract: The present invention relates to a method for pretreating aluminum materials, particularly aluminum wheels, wherein an aluminum material is successively i) cleaned and subsequently rinsed, ii) optionally subjected to alkaline pickling and subsequently rinsed, iii) optionally contacted with an aqueous composition comprising at least one mineral acid, iv) optionally rinsed and v) contacted with an acidic aqueous composition comprising a) at least one compound selected from the group consisting of titanium, zirconium and hafnium compounds and b) at least one linear terpolymer prepared by controlled radical polymerisation and comprising vinylphosphonic acid monomeric units, hydroxylethyl- and/or hydroxylpropyl-(meth)acrylate monomeric units and (meth)acrylic acid monomeric units, vi) optionally rinsed, vii) optionally contacted with another aqueous composition, viii) optionally rinsed and ix) optionally dried. Further, the invention relates to a corresponding composition as well as the use of the materials treated according to the method.
Patent EP-3678725-A1 (EP)
Inventor: ISAACSON S RAY
IPC: A61M25/00
Filed: 2018-08-22
Abstract: A connector device includes a connector. An electrical lead wire is positioned in the connector. The electrical lead wire is configured to provide communication between the connector device and an external device. In certain embodiments, the electrical lead wire includes a contact point on a surface of the connector for electrically coupling the connector device to the external device. In addition to or as an alternative to the electrical lead wire, the connector device may include an optical coupling or channel in the connector configured for optical light transmission between the connector device and the external device.