baber/WOPTO huggingface dataset:
Patent BR-112022021957-A2 (BR)
Title: Imidazopirimidinas como moduladores de il -17
Inventor: XIAOHUA XUE
IPC: A61P29/00
Filed: 2021-04-28
Abstract: IMIDAZOPIRIMIDINAS COMO MODULADORES DA IL-17. A presente invenção revela compostos da Fórmula I: ou sal farmaceuticamente aceitável do mesmo, em que R1 , R2 , R3 , R4 e R5 estão definidos no relatório descritivo, bem como métodos de preparo e uso dos compostos aqui revelados para tratar ou melhorar uma síndrome, distúrbio e/ou doença mediada por IL-17.
Patent BR-112022022003-A2 (BR)
Title: Método para aprimorar imunogenicidade de antígeno de proteína/peptídeo
Inventor: LIANGZHI XIE
IPC: A61K39/00
Filed: 2021-04-29
Abstract: MÉTODO PARA APRIMORAR IMUNOGENICIDADE DE ANTÍGENO DE PROTEÍNA/PEPTÍDEO. Trata-se de um método para aprimorar a imunogenicidade de um antígeno de proteína/peptídeo, em que o método compreende conjugar um antígeno de proteína/peptídeo com um açúcar para formar um conjugado de antígeno de glicoproteína/peptídeo, que aprimorou a imunogenicidade em comparação com um antígeno de proteína/peptídeo não conjugado. Em particular, o método envolve conjugar um patógeno, tal como um antígeno de proteína de superfície viral ou um fragmento do mesmo, com um polissacarídeo, em particular um polissacarídeo capsular de Streptococcus pneumoniae. O conjugado com imunogenicidade aprimorada pode ser usado para prevenir ou tratar doenças causadas por patógenos, em particular doenças causadas por coronavírus.
Patent CZ-63292-A3 (CZ)
Inventor: OUHRABKA JIRI
IPC: F23K3/00
Filed: 1992-03-04
Abstract: Samospádové zařízení pro dávkování druhotných sypkých
paliv do kotlů s posuvným roštem je tvořené ze zásobníku
na druhotná paliva /24/ ukončeným regulačními elementy
dávkování /23/ nalézající se nad propadovou skříní /21/,
která je na spodním konci uzavíratelná klapkou /22/ nalézající
se v mezeře /12/, oddělující těleso kotle /10/ a hlavu
kotle se zásobníkem na uhlí /11/.
Patent CZ-70492-A3 (CZ)
Title: Analogs of carboxy-terminal octapeptide (b-23-b-30) of a human insulin chain with a modification in positions b-24 and b-25
Inventor: BARTH TOMISLAV RNDR DRSC
IPC: C07K14/62
Filed: 1992-03-10
Abstract: The synthetic analogues of the carboxyterminal sequence of the B-chain of human insulin with a variation of amino acids in position B-24 and/or in position B-25 of the general formula:Gly-X-Y-Tyr-Thr-Pro-Lys-Thr23 24 25 26 27 28 29 30whereX is D-Phe Y is D-Phe (substance I)X is L-Phe Y is L-p-MePhe (substance II)X is L-Phe Y is D-p-MePhe (substance III)X is L-Phe Y is L-p-EtPhe (substance IV)X is L-Phe Y is D-p-EtPhe (substance V)X is L-p-MePhe is L- Phe (substance VI)X is D-p-MePhe Y is L- Phe (substance VII)X is L-p-EtPhe Y is L- Phe (substance VIII)X is D-p-EtPhe Y is L- Phe (substance IX)The substances are prepared by synthesis on a solid phase using the Boc/Biz protective strategy from the hydroxylbenztriazolic esters of individual amino acids whose possible side hydroxyls are protected, the hydroxyl of tyrosine by the 2.5-dichlorobenzyloxycarbonyl group, and the hydroxyl of threonine by the benzyl group.
Patent CZ-35399-A3 (CZ)
Inventor: WEBER NORBERT
IPC: F15B1/14
Filed: 1997-06-06
Abstract: Způsob zhotovení membránového zásobníku s kovovým
tělesemzásobníku a pružně poddajným oddělovacímčlenem,
zvláště ve tvarumembrány (17) v následujících krocích: a)
přivedení trubky (1) do rotace podéljejí delší osy; b)
předehřátíjednoho konce (5) trubky (1) za účelemtváření
tažením za tepla metodou vytlačování válcováním; c)
válcování konce (5) trubky pomocí nejménějednoho
zaoblovacího nože při cíleném ohřevujeho pracovní oblasti
(11) na vně vyhnutém límci (9); d) měření pracovní teploty
v pracovní oblasti tlakového nástroje běhemtváření aregulace
teploty na hodnotu pro optimální tváření; e) vytvoření vnitřní
prstencové drážky (15) ve střední části truhly (1); f) vsazení
sestavy membrány (17) do kruhové drážky (15) pomocí
příslušného upínacího prstence (19); a g) vytvoření druhého
dna (23) na druhém konci (21) v krocích podle b) a c).
Patent CZ-40295-A3 (CZ)
Title: Holder of a nozzle plate and spinning beam
Inventor: KRETZSCHMAR WILLI
IPC: D01D4/00
Filed: 1994-06-20
Abstract: Mounting system for spinarette jets has holders at the spinning beam for jet plates to be inserted upwards from below, with a twisting locking action. The supports at the mantle surface and the holding component within the holder face each other radially. Also claimed is a spinning beam with holders (2) near the jet plates (9) with shoulders (23) extending inwards, opposite the supports (24) at the jet units (6). The jet units (6) can rotate in the holders (2) so that the supports (24) and shoulders (23) slide against each other to lock the jet units (6) axially within the holders (2).
Patent CZ-9900745-A3 (CZ)
Inventor: MUSIL ADOLF ING
IPC: A61L9/03
Filed: 1999-03-02
Abstract: Reduktor plynů s mikrobiálním účinkem, zejména k přeměně
ozónu na kyslík tvořený válcovitým tělesem (1), válcovitým
pláštěm (2) a válcovitým pouzdrem (3) umožňuje záchyt
mikroorganismů a přeměnu plynů.
Patent SK-12196-A3 (SK)
Title: Spread with aqueous continual phase
Inventor: UNDERDOWN JEFFREY
IPC: A23D7/015
Filed: 1994-07-20
Abstract: PCT No. PCT/EP94/02396 Sec. 371 Date Jan. 23, 1996 Sec. 102(e) Date Jan. 23, 1996 PCT Filed Jul. 20, 1994 PCT Pub. No. WO95/03707 PCT Pub. Date Feb. 9, 1995A water-continuous spread containing from 0.1 to 20 wt. % of fat, said spread being a W/O/W emulsion comprising hydrolysed starch with a DE of 1-6 in the external phase at a concentration above its critical gelling concentration, said spread having a stress strain relation with a maximum stress occurring at a strain of 0.001-1, the maximum stress at this strain being 0.01 to 100 kPa and with a ratio of plastic stress and the maximum stress of 0.1 to 1.
Patent SK-21193-A3 (SK)
Title: Process for assessing the quality of an object or state
Inventor: BRANDES BERND
IPC: G01N27/00
Filed: 1991-09-17
Abstract: A method and apparatus is provided for monitoring a variable in a system. Actual values of the variables are sensed to produce sensed values. An initial threshold is set below an initially sensed value by a predetermined difference. Thereafter, the threshold is selectively maintained constant and adjusted to follow below the sensed values by a difference which is a function of the sensed values if the sensed values remain constant or increase, with the threshold remaining constant if the sensed values decreases. The threshold is compared with the sensed values and an indication of an unsatisfactory quality is provided if the sensed values fall below the threshold.
Patent SK-30295-A3 (SK)
Title: Device for color photograph printing
Inventor: ZOGGIA ANTONIO
IPC: G03B27/73
Filed: 1994-06-08
Abstract: PCT No. PCT/IT94/00079 Sec. 371 Date Mar. 2, 1995 Sec. 102(e) Date Mar. 2, 1995 PCT Filed Jun. 8, 1994 PCT Pub. No. WO95/02849 PCT Pub. Date Jan. 26, 1995A device for printing color photographs on photosensitive paper having a segmented filter positioned relative to an inverting and focusing lens at a point where an original image projected through the lens at the paper is inverted. The segmented filter has colored segments corresponding to the primary colors to which the photosensitive paper is sensitive. The colored segments each have a surface area in a ratio corresponding to the relative sensitivity of the paper to the color of the segment. In an alternate embodiment, the filter has equal sized colored components and is moved with respect to an optical axis of the lens to adjust the intensity of each filtered monochromatic image projected onto the paper.
Patent SK-62198-A3 (SK)
Inventor: DLOUHY JAN
IPC: E04C1/40
Filed: 1998-05-11
Abstract: Stavebný prvok z biohmoty pozostávajúci z vonkajšej
steny, vnútornej steny, bofiných stien, ktoré tvoria zámky,
a z otvorov obsahuje 77 % až 90 % hmotn. na báze
drevnej štiepky, 5 až 8 % hmotn. cementu, 4 až 8 %
hmotn. vody a prísad, pričom zámok je tvorený perom
(6) a jeho tvarom zodpovedajúcou drážkou (8), kde pero
(6) prvou klinovou plôškou (5) prechádza do prvej
rovnej plochy (4) a jemným zaoblením krajov (3) do
vonkajšej steny (1) a druhou klinovou plôškou (7) do
drážky (8), ktorá treťou klinovitou plôškou (9) prechádza
do druhej rovnej plochy (10) a jemným zaoblením
krajov (3) do vnútornej steny (2). Stavebný prvok ďalej
obsahuje farbivá. Stavebný prvok okrem výplňových
vnútorných otvorov (II) obsahuje aj izolačné vonkajšie
otvory (13).
Patent SK-77198-A3 (SK)
Title: Consumer article comprising a wc basket unit and re-fill bottle
Inventor: TURK ERICH
IPC: E03D9/02
Filed: 1996-12-05
Abstract: A packaging configuration includes a lavatory basket and a refill bottle assembly interconnected for storage, shipping and sale. The refill bottle assembly includes a refill bottle containing a cleaning agent for refilling the container of the lavatory basket during use, and a closure cap for sealing attachment with the outlet of the refill bottle. The lavatory basket includes a container for holding and selectively dispensing the cleaning agent, and a securing element extending therefrom. The container is configured to be releasably attached to a concave upper surface of the closure cap of the refill bottle by means of a projection tab on the closure cap in locking engagement with a corresponding recess in a wall of the container. A releasable connection is provided between the securing element and the refill bottle assembly to further secure the container to the refill bottle assembly.
Patent CH-685658G-A3 (CH)
Title: Dual function analogue wrist watch
Inventor: SCHLUP WALTER
IPC: G04B47/04
Filed: 1994-04-06
Abstract: An outer ring (3) is attached to the casing of the watch (1) by means of a hinged joint (6) attached near to the point of attachment of the strap. The ring has two opposed faces (7,8) each of which can be made visible by turning the ring about the hinge and folding it down on to the casing in the corresponding direction. One of the two ring faces may provide a decorative finish, whilst the other may provide an indication of the time zones around the world. The hinge for the ring is mounted at the 12 o'clock position around the watch face, whilst the fastening is mounted at the 6 o'clock position.
Patent CH-676307G-A3 (CH)
IPC: F41G3/26
Filed: 1987-11-02
Abstract: The arrangement for shot simulation with a shot simulator and at least one target is characterized in that the target has a device for emitting light of a wavelength outside the visible wavelength range and the shot simulator has a receiving device for the light. The shot simulator also possesses a device for measuring the period of time between the detection of the target as a result of the emitted light and the firing of a simulated shot. By means of this arrangement, the reaction time required by the gunner between the detection of the target, the identification of the latter and the firing of a shot and a hit can be measured effectively.
Patent CZ-161992-A3 (CZ)
Title: Filament of a hollow three-lobe cross-section and a plate-like spinning nozzle for producing thereof
Inventor: YEH LING
IPC: D01D4/02
Filed: 1992-05-28
Abstract: A multilobal synthetic polymeric filament has a single approximately axially extending central void. The total cross-sectional void area of the filament is between about 3 and about 10 percent void. <IMAGE>
Patent CZ-872188-A3 (CZ)
Title: Mobile machine for distributing and profiling of a track ballast bed
Inventor: THEURER JOSEF ING
IPC: E01B27/02
Filed: 1988-12-23
Abstract: Track-mobile machine (1) for distributing and profiling the bedding ballast of a railway track formed from sleepers and rails, with a machine frame supported on rail-mounted bogies and having a driving gear (10) and a driving cabin. On the machine frame (6), there is provided a levelling arrangement or ballast plough arrangement (21) which is height-adjustable via a drive and which extends from one longitudinal side of the machine to the other or from one sleeper end region to the one lying opposite. There is assigned to the central section, situated between the rails, of the levelling arrangement or ballast plough arrangement (21), or its central plough elements or working elements (22), an additional ballast conveyor (23) provided in the track-centre region. This is formed by at least one sweeping brush (27, 28) with radially projecting flexible sweeping elements (29), which is height-adjustable via a drive (24), designed to be rotatable about an axis (25) running in the longitudinal direction of the machine and connected to a rotary drive (26). 
<IMAGE>
Patent CZ-130794-A3 (CZ)
Title: Method of exhausting dust fro a reactor and apparatus for making the same
Inventor: RUELLE JEAN-JACQUES
IPC: B65G53/08
Filed: 1994-05-27
Abstract: Process for discharging a reactor by means of a device including at least one densification zone (3) in which the volume available for the powder is decreased without, however, compacting it. Device for discharging a reactor, including at least one densification zone. <IMAGE>
Patent CZ-147393-A3 (CZ)
Title: Process for preparing phytostigminecarbamate derivatives from phytostigmine
Inventor: LEE GEORGE E
IPC: C07D487/04
Filed: 1993-07-21
Abstract: This application relates to a new process for the preparation of a product of the formula   <IMAGE> (I)  wherein R, R1, R2, X and m are as defined within, which process comprises preparing treating a compound such as physostigmine to form eseroline which is then treated with an appropriate compound or its equivalent. Acetic acid is added to the reaction mixture after the formation of eseroline.
Patent CZ-154697-A3 (CZ)
Title: Use of non-peptidic antagonists of bradykinin for treating and prevention of chronic fibrogenetic diseases of livers, acute diseases of livers and complications connected therewith
Inventor: HEITSCH HOLGER
IPC: A61K31/4709
Filed: 1997-05-20
Abstract: Use of non-peptide bradykinin antagonists and their salts is claimed to treat chronic fibrogenetic liver disease (liver cirrhosis and liver fibrosis), acute liver disease and to prevent complications. Preferably the non-peptide bradykinin antagonist is a compound of formula (I). D-D' = X3=X2-X1=N, X4-C(R3)=N, N=C(R3)-X4, X4-CO-X4, CR3)=C(R3)-O; E = 1-4C alkyl, 1-4C alkylthio, 1-4C alkoxy (all optionally substituted by F), H, halo etc.; X1-X3 = N or optionally substituted CH; X4 = O, N or NR7; R1, R2 = H, halo, 1-4C alkyl or 1-4C alkoxy; R3 = H, halo, 1-6C alkyl, 6-12C aryl, (1-3C alkyl)(6-12C aryl), 3-5C alkenyl, 1-4C alkoxy, CO2H etc.
Patent CZ-157896-A3 (CZ)
Title: Highly active catalytic system for poly/ethyleneterephthalate/ synthesis
Inventor: PO RICCARDO
IPC: C08G63/82
Filed: 1996-05-30
Abstract: In the present invention, a class of catalysts is described, to be used in the polycondensation stage in the synthesis of poly(ethylene terephthalate), constituted by a composition of metal derivatives in quantity so that the content of these in the final polymer is below 130 ppm.
Patent CZ-161394-A3 (CZ)
Title: The use of protein exhibiting activity on lysplasminogen or progenitor
Inventor: EIBL JOHANN DR
IPC: A61K38/48
Filed: 1994-07-01
Abstract: A treatment of ischemia and the attendant reperfusion injury entails the administration plasmin and plasmin-forming proteins, including lys-plasminogen and similar substances. Lys-plasminogen, which can be obtained from the proteolytic cleavage of glu-plasminogen, has been found to have a protective effect on tissue that has been injured by ischemic conditions. The administration of lys-plasminogen can used to treat subjects during the time of reperfusion and after reperfusion has already occurred. Lys-plasminogen also can be administered in conjunction with clot lysis therapies, such as those that employ tissue plasminogen activator and the like. <IMAGE>
Patent CZ-170398-A3 (CZ)
Title: Process and apparatus for for controlling distribution of brake power in a vehicle
Inventor: PRUHS UWE
IPC: B60T8/24
Filed: 1997-09-04
Abstract: The invention concerns a process and a device for controlling the distribution of braking force between the front and rear axles of a vehicle. At least when travelling curves, the braking force is individually adjusted on the rear wheels so that the difference between the speed of the rear wheel and a front wheel speed assumes predetermined values.
Patent CZ-178698-A3 (CZ)
Title: Body temperature controlling slips
Inventor: CHUNG SEUN YUNG
IPC: A41B9/02
Filed: 1996-12-11
Abstract: PCT No. PCT/KR96/00238 Sec. 371 Date Jun. 12, 1998 Sec. 102(e) Date Jun. 12, 1998 PCT Filed Dec. 11, 1996 PCT Pub. No. WO97/21363 PCT Pub. Date Jun. 19, 1997Men's pants (shorts or briefs) have a Y type separation band (2) or a U type separation band (22) inside thereof together with separation pads (7, 77) to separate the testicles from the body, the penis from the testicles, and the penis from both hips. Complete separation around the male genitals is achieved without effort by wearing these pants. A penis band (3) formed with an elastic band (4, 44) and clips (5, 55) is sewn to a center part of a waist band (6) in an I shape. A penis hole (14) can be adjusted by moving the two clips (5, 55) up and down according to the individual location and size of the penis (101). A lower part (88) below the clip (5) helps to increase separation between the testicles and the penis.
Patent CZ-179693-A3 (CZ)
Inventor: BITTNER MIROSLAV
IPC: E04B9/22
Filed: 1993-09-01
Abstract: Obklad sestává z kotevních šroubů (2), v pravidelných odstupech uchycených na obkládané ploše (1), na kotevních šroubech (2) mezi horní opěrou (3) a dolní šroubovací opě- rou (4) za okraj (5) uchycených kazet (6) a z krycích lišt (7), sevřených mezi kazetami (6), spojenými navzájem bočně pomocí pružných tahových elementů (8) napjatých mezi úchyty (9) kazet (6).
Patent CZ-192698-A3 (CZ)
Inventor: SCHALLER PAVEL
IPC: D06F7/00
Filed: 1998-06-18
Abstract: Pomůckakpraní, zejménav bubnových pračkách, tvořenátělesem
/1/, dutýma kulovitým, s povrchems výstupky!2J nebo otvory/5/
I různých tvarů a kulovitýmtělesem/3/ vdutině/4/tělesa/l/,jiné,
Ί menší velikosti tělesa/1/.
Patent CZ-201432-A3 (CZ)
Inventor: SEDLÁČEK VLASTIMIL
IPC: F01D9/04
Filed: 2014-01-16
Abstract: ﻿Způsob výroby dýzového segmentu se provádí tak, že tělo dýzového segmentu se vysoustruží do tvaru písmene „U“, kdy do vzniklých ramen (1) těla dýzového segmentu se vyříznou otvory (2) pro lopatky (3). Po vložení lopatek (3) se osoustruží obě vnější části ramen (1) těla dýzového segmentu a segment se vloží do nosiče (4). Spojovací dno (5) těla dýzového segmentu se odsoustruží, čímž se vytvoří přístup k lopatkám (3).
Patent CZ-237493-A3 (CZ)
Title: Process for preparing novel metal complexes of n-beta-hydroxyalkyltri -n- carboxyalkyltri-1,4,7,10-tetraazacyclododeca and n-beta-hydroxyalkyltri -n- carboxyalkyl-1,4,8,11-tetraazacyclotetradecane derivatives
Inventor: PLATZEK JOHANNES DR
IPC: C07D257/02
Filed: 1993-11-05
Abstract: A novel process is described for the preparation of metal complexes of N- beta -hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclo-dodecane and N- beta -hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraaza-cyclotetradecane derivatives.
Patent CZ-286496-A3 (CZ)
Title: Eye preparation containing hydrophilic polymer responsive to ions and inorganic salt in a ratio, at which it exhibits low viscosity
Inventor: LEHMUSSAARI KARI
IPC: A61K9/00
Filed: 1995-03-29
Abstract: PCT No. PCT/FI95/00167 Sec. 371 Date Mar. 15, 1996 Sec. 102(e) Date Mar. 15, 1996 PCT Filed Mar. 29, 1995 PCT Pub. No. WO95/26712 PCT Pub. Date Oct. 12, 1995The present invention is directed to an ophthalmic composition in the form of a topical aqueous solution consisting essentially of an ophthalmologically active agent containing basic groups, an ion sensitive, hydrophilic polymer containing acidic groups in an amount of 0.004 to 1.5% by weight, at least one salt selected from the group of inorganic salts and buffers in a total amount of from 0.01 to 2.0% by weight, and optionally a wetting agent and a preservative, the ratio between salt and polymer being such that the solution exhibits a viscosity of less than 1000 mpas, and the pH of the solution is 4.0 to 8.0. The composition contains a sufficient amount of polymer to provide for a controlled absorption of the drug into the eye, its viscosity having been reduced to provide for better handling characteristics.
Patent CZ-296296-A3 (CZ)
Title: Set for opening and closing valve closures
Inventor: ZEUSNIK JOACHIM
IPC: F16K31/50
Filed: 1996-10-10
Abstract: The fitting opens or closes a shut-off valve (11) which is underground, or in a position which is difficult to access. It has a square rod (2) which can reach as far as the valve, and which is especially in the form of a telescopic rod which is secured by a locking system. The rod has a sleeve tube (5,6) which can be inserted into a bell-shaped element (7,8) which surrounds the connection between a coupling sleeve (14) and a valve spindle (12). The coupling sleeve has a spacer (24) which is associated with the bell-shaped element, in order to prevent the rod from being pulled from the spindle. The spacer combines with a sealing disc (16), which acts as a stop, and which forms a dirt seal towards the valve, while a sealing disc (3) on an edge cap (4) which is connected to the rod, seals towards the free end of the latter.
Patent CZ-317398-A3 (CZ)
Title: Jet chamber of flat textile drying ovens
Inventor: ONDROUCH VLASTIMIL ING
IPC: D06B1/02
Filed: 1998-10-02
Abstract: The invented jet chamber of a flat textile drying ovens contains at least one trough-like section (1) being provided with a nozzle plate (5) and a drying air inlet hole (10). The jet chamber is separated in transversal direction over all the trough-like sections (1) into a front section (6) and a rear section (7), whereby both these sections (6, 7) are coupled with each other in detachable manner.
Patent CZ-339597-A3 (CZ)
Title: Valve mechanism
Inventor: KARLSSON PER
IPC: F16K31/363
Filed: 1996-04-24
Abstract: PCT No. PCT/SE96/00545 Sec. 371 Date Jan. 16, 1998 Sec. 102(e) Date Jan. 16, 1998 PCT Filed Apr. 24, 1996 PCT Pub. No. WO96/34219 PCT Pub. Date Oct. 31, 1996A valve device for influencing an overpressurized flow of media comprises a control valve for controlling the flow of media, and a closing valve which is either totally open or totally closed to stop the flow. The valves are arranged in a common valve housing and can seal independently of each other against a common valve seat. The valve seat presents an outlet side which forms the outlet channel of the valve device. The valve device can be made compact, and the number of necessary redirections of the flow of media is minimized.
Patent CZ-359098-A3 (CZ)
Title: Circumferential structure for elevator machinery
Inventor: MARTINI ANGELO
IPC: B66B11/00
Filed: 1997-05-05
Abstract: Containing structure (10) for a lift machinery, the structure being made of metal or other suitable material, consisting of a housing (18) in which at least one of the constituent walls is defined by leaves hinged to a permanent wall (14) of the building or to another wall of the housing (18). The object of the present invention is to provide a containing room or structure for lift machinery, occupying very little space and at the same time providing enough space for maintenance work. A permanent fixed room within the building for the lift machinery is not required.
Patent ES-461198-A3 (ES)
Title: A method and a concentrator for concentrating the heating effect of rays emitted from a source of energy moving in a trajectory.
IPC: F24J/
Filed: 1977-07-30
Abstract: This invention refers to a method and a system for using radiant energy, and more particularly, it refers to a concentrator, a method and a system for concentrating rays emitted from an energy source and deriving work from the heating effect of the concentrated rays.