baber/WOPTO huggingface dataset:
Patent CA-2584758-A1 (CA)
Title: Mix, some of best and novel cloning techniques
Inventor: VOON GERARD
IPC: C12N15/85
Filed: 2007-04-02
Abstract: Three parts of animal Cloning techniques not well known just below are to be incorporated to all the techniques below (Source of Cells):     1. Leaving the host's cytoplasm - and proteins all is left in the Oocyte (which we will try fertilized or unfertilized) except the nucleus is removed.   2. The second is to starve the tissue cultured cells (which has the DNA you want to clone) before micro injection into the host Oocyte and electrical or heat shock to fuse the injected DNA with the host Oocyte cytoplasm. This seems to be the trick to cause the cells to multiply into a blastocyst.   3. We also plan to add ligase and polymerase, polyethylene glycol and other such DNA  helping binding enzymes (ase... ) to the DNA donor to be cloned animal/person/plants.     Sources of cells include (the following techniques are more cloning then in vitro since the resulting tissue are the same DNA as the Adult, making the artificially grown organs, neurons and muscles blood, bone marrow cells compatible, and solving the tissue rejection problem:
Patent CA-2585735-A1 (CA)
Title: Novel compounds of substituted and unsubstituted adamantyl amides
Inventor: LE PHUONG THI QUY
IPC: C07D241/04
Filed: 2005-10-20
Abstract: The present invention relates to compounds with the formula (I) or a pharmaceutically acceptable salt thereof: The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of 11-~-hsd-1, the method comprising administering to a mammal an effective amount of a compound of formula (I).
Patent CA-2587143-A1 (CA)
Inventor: HANSEN HANS J
IPC: A61K39/395
Filed: 2005-12-08
Abstract: Methods and compositions for immunotherapy of inflammatory and immune-dysregulatory diseases, using multispecific antagonists that target at least two different markers are disclosed. When the multispecific antagonist reacts specifically with a target associated with an inflammatory or immune-dysregulatory disorder, with a pathologic angiogenesis or cancer, or with an infectious disease, it also binds specifically with at least one proinflammatory effector of the immune system or at least one coagulation factor. Thus, the multispecific antagonist contains at least one binding specificity related to the diseased cell or condition being treated and at least one specificity to a component of the immune system. The multispecific antagonists are used in the treatment of various diseases that are generated or exacerbated by, or otherwise involve, proinflammatory effectors of the innate immune system or coagulation factors.
Patent CA-2588063-A1 (CA)
Title: 2-methylene-19,21-dinor-1.alpha.-hydroxy-bishomopregnacalciferol
Inventor: DELUCA HECTOR F
IPC: A61K31/59
Filed: 2005-11-18
Abstract: Compounds of formula I are provided where X1 and X2 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
Patent CA-2589496-A1 (CA)
Title: Defoamer emulsion compositions for pulp mill applications
Inventor: SHEEPY JOHN M
IPC: C08K5/00
Filed: 2005-12-08
Abstract: An oil-in-water emulsion useful as a defoamer for pulp and paper mill applications is described. The defoamer has an oil blend (of a triglyceride oil or a mixture of triglyceride oils and silicone), a stabilizing agent (to make the oil blend stable in the emulsion), hydrophobic silica particles, surfactants, dispersants, and other components. The emulsion is usable directly at low concentrations to control foam.
Patent CA-2590836-A1 (CA)
Title: Compositions for articles comprising replicated microstructures
Inventor: COYLE DENNIS JOSEPH
IPC: C09D4/00
Filed: 2005-12-01
Abstract: The present invention provides novel curable compositions useful in the preparation of light management films and other optical articles. The curable compositions comprise (a) at least one silicone-containing surfactant, (b) at least one a multifunctional (meth)acrylate having structure I; in certain embodiments (c) at least one nanoparticulate filler; and in certain embodiments, (d) at least one monofunctional (meth)acrylate. The curable compositions may be cured to provide the corresponding cured compositions and articles made therefrom.
Patent CA-2592026-A1 (CA)
Title: Thermoplastic compositions and method of use thereof for molded articles
Inventor: WINOWIECKI KRIS W
IPC: C08K5/09
Filed: 2005-12-21
Abstract: A polyolefin composition containing elastomers (plasticizers), crystalline polypropylene, modified by mixing with polybutene-l and a coupling agent and a bicyclic dicarboxyl acid salt nucleating agent and/or a lubricant which comprises an unsaturated fatty acid ester which acts as a surface modifier in a molded article is described. The composition is adapted to be used with pigments to make finished molded articles which have an appearance of paint covered by a clear coat and which are scratch resistant and have good low temperature (-30 ~C) impact properties.
Patent CA-2593137-A1 (CA)
IPC: A47F3/00
Filed: 2007-07-05
Abstract: An adjustable pusher tray mountable on a top of a shelf for holding objects thereon. The tray includes a platform adapted to be mounted on the top of the shelf; and at least one pushing device adapted to be mounted on the platform for pushing the objects towards a front of the tray. Each pushing device has a longitudinal plate adapted to be mounted on the platform, a pusher tab slidably mounted on the longitudinal plate, and a coiled spring having one end mounted on the pusher tab and another end mounted on the longitudinal plate for biasing the pusher tab against the objects positioned between the pusher tab and the front of the tray.
Patent CA-2595717-A1 (CA)
Inventor: SUZUKI HIROMASA
IPC: B01J23/46
Filed: 2006-01-19
Abstract: A catalyst for purifying exhaust gases includes a support substrate, and a catalytic loading layer. The support substrate has an exhaust-gas flow passage. The catalytic loading layer is formed on a surface of the exhaust-gas flow passage, and is composed of a porous oxide support and a catalytic ingredient. The catalytic loading layer includes an Rh area, and an oxidizing area. On the Rh area, rhodium is loaded as the catalytic ingredient. The oxidizing area is formed on an exhaust-gas flow downstream side with respect to the Rh area. On the oxidizing area, a catalytic ingredient exhibiting an oxidizing activity at least is loaded. Also disclosed is an exhaust-gas purification controller using the same.
Patent CA-2597349-A1 (CA)
Inventor: FORT PHILIPPE
IPC: A61K31/513
Filed: 2006-02-10
Abstract: Pyrimidine derivatives (I) are used as acetylcholinesterase inhibitors. Pyrimidine derivatives of formula (I) are used as acetylcholinesterase inhibitors. R 1, R 3 = H or optionally unsaturated 1-6C (cyclo)alkyl (optionally substituted by OH or halo); R 2 = aryl group (optionally substituted) or 1-4C optionally unsaturated (cyclo)alkyl (optionally substituted by halo, OH or heterocycle containing 1-5C and 1-5 heteroatoms selected from O, S or N); X 1 = S, N or O; X 3-X 5 = C or N, provided that no more than two are N; and Y 1 = O or S. Independent claims are also included for: (1) an insecticidal composition (II) comprising (I) together with a support to use (II) as an insecticide; and (2) an insecticidal kit comprising (II) associated with a diffusion means allowing the application of (II) on agricultural, dwelling, forest, marshy, steppe and/or savanna zones. [Image] ACTIVITY : Insecticide; Neuroprotective; Nootropic. MECHANISM OF ACTION : Acetylcholinesterase inhibitor. The ability of (I) to inhibit acetylcholinesterase was tested. The results showed that 5-[(5-methyl-2-furyl)methylene]-1-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione exhibited IC 50 value of 1.57 mu M and 0.65 mu M against mutated and normal acetylcholinesterases respectively.
Patent CA-2597833-A1 (CA)
Title: Pyrazolopyrimidines
Inventor: HEINEMANN ULRICH
IPC: A01N43/56
Filed: 2006-02-07
Abstract: The invention relates to the pyrazolopyrimidines of formula (I), wherein R1, R2, R3, R4, R5, and X are defined as in the description. The invention also relates to methods for producing said substances and to the use thereof for controlling undesirable microorganisms.
Patent CA-2599054-A1 (CA)
Inventor: AUSTIN MICHAEL
IPC: A61F2/84
Filed: 2006-02-01
Abstract: A medical appliance is provided that includes an outer sheath (13) adapted to enclose a self-expanding stent (12) in an inner space before deployment of the self-expanding stent and an inner sheath (16) arranged between the outer sheath and the self-expanding stent before deployment of the self-expanding stent. The inner sheath includes longitudinal slits (21a - 21d) that extend from a distal end of the medical appliance to the proximal end. The longitudinal slits form a plurality of inner sleeve tails (20a - 20d). The medical appliance also includes an actuator (70) adapted to move the outer sheath with respect to the inner sheath during deployment of the self-expanding stent. The actuator is adapted to cause the outer sheath to move proximally. A method of deploying a self-expanding stent is provided. A method of loading a delivery mechanism is provided.
Patent CA-2599669-A1 (CA)
Inventor: SUGIMOTO YOSHIKAZU
IPC: G01N33/537
Filed: 2006-02-28
Abstract: It is intended to establish an immunoassay method for human OPRT. An assay method for human orotate phosphoribosyltransferase protein using an anti-human orotate phosphoribosyltransferase antibody that recognizes an epitope present in an amino acid region between positions 86 and 108 from the N-terminus of human orotate phosphoribosyltransferase and an anti-human orotate phosphoribosyltransferase antibody that recognizes an epitope present in an amino acid region between positions 454 and 474 from the N-terminus of human orotate phosphoribosyltransferase in combination.
Patent CA-2600820-A1 (CA)
Title: Device and method for the treatment of diseased tissue such as tumours
Inventor: PACEY ANDREW
IPC: A61B18/14
Filed: 2006-03-09
Abstract: A device for the treatment of tumours comprising an elongate catheter (102), a plurality of flexible needles (402) confined within the catheter which, when extended therefrom, take up a curved form and which, together, define a structure for surrounding a tumour to be treated; the needles being arranged to heat and embolise a shell of tissue surrounding the tumour, thereby cutting off the tumour's blood supply. The invention further extends to a method of treatment using such a device.
Patent CA-2601724-A1 (CA)
Title: Composes en serie triterpenes tetracycliques, leurs procedes de preparation, leurs applications comme medicaments et les composes pharmaceutiques les renfermant
Inventor: GUILLOU CATHERINE
IPC: C07J71/00
Filed: 2006-01-13
Abstract: La présente invention concerne un alcaloïde triterpénique de formule général e suivante (I). Elle concerne en outre son procédé de fabrication et son utilisation à titre de médicament.
Patent CA-2602585-A1 (CA)
Inventor: ELLIS PHIL RONALD
IPC: G01N33/53
Filed: 2006-03-30
Abstract: The invention relates to a method for determining a prognosis for a cancer by quantifying vitamin receptor expression on the cancer cells. The method comprises the steps of quantifying vitamin receptor expression on the cancer cells, and determining a prognosis for the cancer. The invention also relates to methods and kits for determining the presence of vitamin receptors on cancer cells to select patients that should be treated with a therapy that utilizes vitamin receptor targeting and to develop a treatment regimen for such patients. The invention further relates to kits for performing the methods.
Patent CA-2603143-A1 (CA)
Inventor: HUNT TERRENCE J
IPC: A61K38/48
Filed: 2006-07-24
Abstract: A high potency botulinum toxin pharmaceutical composition comprising two excipients (such as albumin and sodium chloride) in a weight to weight ratio of between about 1 and about 100.
Patent CA-2603146-A1 (CA)
Title: Method and apparatus for singular value decomposition of a channel matrix
Inventor: OLESEN ROBERT LIND
IPC: H04B7/02
Filed: 2006-03-30
Abstract: A method and apparatus for decomposing a channel matrix in a wireless communication system are disclosed. A channel matrix H is generated for channels between transmit antennas and receive antennas (202). A He.pi.nitian matrix A=HHH or A=HHn is created (204). A Jacobi process is cyclically performed on the matrix A to obtain Q and DA matrixes such that A=QDAQH (206).  DA is a diagonal matrix obtained by singular value decomposition (SVD) on the A matrix. In each Jacobi transformation, real part diagonalization is performed to annihilate real parts of off-diagonal elements of the matrix and imaginary part diagonalization is performed to annihilate imaginary parts of off -diagonal elements of the matrix after the real part diagonalization. U, V  and DH matrixes of H matrix are then calculated from the Q and DA matrices. DH  is a diagonal matrix comprising singular values of the H matrix (208).
Patent CA-2605789-A1 (CA)
Inventor: KIM HEE SEUNG
IPC: H04M1/72412
Filed: 2006-04-25
Abstract: L'invention concerne un système de commande de lecteur RFID et un procédé associé. Un protocole de commande d'un lecteur RFID et une unité de commande du lecteur RFID d'un téléphone mobile sont définis. Des messages, des informations, des commandes, des réponses et des notifications sont établies et transmises entre le lecteur RFID et l'unité de commande de celui-ci.
Patent CA-2606258-A1 (CA)
Inventor: KIM CHOON-GIL
IPC: C07D257/04
Filed: 2006-04-21
Abstract: Azole compounds containing carbamoyl group and pharmaceutically useful salts thereof are described. The compounds are effective anticonvulsants which are used in the treatment of disorders of the central nervous system, especially as anxiety, depression, convulsion, epilepsy, migraine, bipolar disorder, drug abuse, smoking, ADHD, obesity, sleep disorder, neuropathic pain, stroke, cognitive impairment, neurodegeneration, stroke and muscle spasm.
Patent CA-2607021-A1 (CA)
Inventor: SHAW STEPHANIE
IPC: C07D473/38
Filed: 2006-05-05
Abstract: This application concerns certain 2-phenylamino-6-aryl amino-, 6-aryloxy-, and 6- arylthio- purines, -azapurines and -deazapurines. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV  treatment.
Patent CA-2608917-A1 (CA)
Title: Waveguide transitions and method of forming components
Inventor: PAYNTER JEFFREY
IPC: H01P3/12
Filed: 2007-10-31
Abstract: A waveguide transition for transitioning from an overmoded waveguide to another waveguide is provided, where one end of the waveguide is configured to connect to a rectangular waveguide and the other end is configured to connect to an elliptical waveguide. The transition has an internal shape having top and bottom walls and two side walls. The top and bottom walls are shaped to join smoothly with waveguides at each end of the transition, while the side walls diminish in height along the length of the transition. The waveguide transition may employ mode filtering to suppress unwanted higher modes. A method of forming waveguide components is also disclosed, involving thixoforming of components in single pieces, the components having internal shapes configured for mold core removal.
Patent CA-2609389-A1 (CA)
Title: Combination therapy comprising a diaryl urea compound and a pi3, akt kinase or mtor inhibitors (rapamycins) for cancer treatment
Inventor: SCHEURING URBAN
IPC: A61K31/4412
Filed: 2006-05-13
Abstract: The present invention relates to pharmaceutical compositions and combinations for treating cancer, comprising a diaryl urea compound e.g. 4 {4- [3- (4-chloro-3-trifluoromethylphenyl) -ureido] -3-fluorophenoxy}-pyridine-2-carboxyli.sigma. acid methylamide and an PI3K/AKT signaling pathway inhibitor.  The PI3K/AKI signaling pathway inhibitor comprises PI3 inhibitors {like celecoxilo, viridins, wortmannins} , AKT kinase inhibitors {like perifosine, triciribine} and mTOR inhibitors {like the rapamycins temsirolimus and evorolimus}.
Patent CA-2610064-A1 (CA)
Title: Vectored air web handling apparatus
Inventor: SOLBERG BRUCE JEROME
IPC: B65H5/22
Filed: 2006-05-31
Abstract: A web control device is provided as a generally cylindrical hollow bar having a plurality of holes disposed thereon. Each of the plurality of holes is capable of providing fluid contact between the central portion and the outer portion of web control device. The web control device provides contact-less support of a moving web material and can reduce the Poisson lateral contraction in a moving and/or tensioned web material without wrinkling or significantly stretching the moving web material.
Patent CA-2610445-A1 (CA)
Inventor: HOHMANN ARNO
IPC: A61C5/64
Filed: 2006-06-01
Abstract: The present invention is directed to a system for storing and dispensing a substance and a method for air free filling of the same. The system comprises at least one compartment for storing a predetermined amount of a substance, wherein said compartment has a back end and a front end for filling and dispensing the substance, respectively. The system further comprises a vent, a movable front plug and a displaceable piston for sealing the compartment at the back end, wherein the compartment defines a predetermined volume between the vent and the movable front plug within the compartment downstream of said piston.
Patent CA-2614957-A1 (CA)
Title: Cable data service method
Inventor: DESAI BHAVESH N
IPC: H04L12/56
Filed: 2002-02-19
Abstract: A data receiving system having at least one input. The data receiving system includes a demodulator system for receiving packets in parallel over multiple channels. A tunneling destination, which is coupled to the demodulator system, receives and serializes the packets from the demodulator system.
Patent CA-2615794-A1 (CA)
Title: Nonwoven fabric and method and apparatus for manufacturing same
Inventor: SWISCZ PAUL
IPC: D04H3/07
Filed: 2000-01-10
Abstract: An apparatus for fabricating a unique nonwoven fabric which has the appearance of a woven fabric includes a supply station for parallel warp yarns, a support structure for orienting the parallel warp yarns into a cylindrical orientation, a weft yarn applicator for wrapping weft yarns around the cylindrically oriented warp yarns after an adhesive scrim has been overlaid onto the warp yarns, a heating station for activating the adhesive and a cooling station for setting the adhesive, and a cutter for severing the cylindrically formed fabric laminate so that it can be flattened and wrapped onto a take-up roller.  The weft yam applicator including a rotating drum wherein a plurality of spools of weft yarn material are mounted in circumferentially spaced relationship and a tensioner is provided for applying the weft yam material around the warp yarns in a predetermined tension which may be the same as, greater than, or less than the tension in the warp yarns.
Patent CA-2617086-A1 (CA)
Title: An aerobic compost tea making device
Inventor: WILSON TIMOTHY J
IPC: C05F17/02
Filed: 2008-01-25
Abstract: The device and method invented provides a unique means to extract and multiply, by the millions, beneficial aerobic microbes found in compost and vermicompost to b e applied to soil and plants in liquid form. This liquid has been named compost tea colloquially. Compared to many compost tea making devices being sold, the invented device is truly simple and can be dismantled and cleaned in under twenty minutes. Most of the parts are not glued and can be pulled apart. The device and method uses air pumps alone to actually circula te the water and can be used with or without a mesh extractor. This is achieved by the insertion of an air diffuser into the piping used, which infuses the water with oxygen while circulating the water, into either, an extractor containing compost or a body of water containing compost. Concurrently additional diffusers infuse the body of water with oxygen.</SDO AB>
Patent CA-2618786-A1 (CA)
Inventor: MATSUDA KUNIO
IPC: G01N27/406
Filed: 2006-04-11
Abstract: Disclosed is a hydrogen gas sensor whose sensing function is hardly affected by the outer space, or a hydrogen gas sensor which hardly affects the outer space. Specifically disclosed is a hydrogen sensor (10) comprising a first electrode (12), a second electrode (14) and an electrolyte (16) which is in contact with these electrodes. The first electrode and the second electrode are made of materials having different chemical potentials to a hydrogen gas.  Namely, the first electrode contains a material having a relatively high chemical potential, and the second electrode contains a material having a relatively low chemical potential. The hydrogen gas sensor senses a hydrogen gas basing on the value of an electromotive force generated between the electrodes, and this sensor is characterized in that at least the joint portion of the electrolyte and the first electrode and the joint portion of the electrolyte and the second electrode are covered with an outer coat (20) which has hydrogen selective permeability.
Patent CA-2620783-A1 (CA)
Title: Methods and apparatus for cardiac valve repair
Inventor: DEEM MARK E
IPC: A61B17/04
Filed: 2000-04-07
Abstract: The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles.  These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools (30, 36, 56) which are introduced to a heart chamber.  Preferably, the tissue structures will be temporarily grasped and held into position prior to permanent attachment.
Patent CA-2624014-A1 (CA)
Title: Semiconductor optical element and external cavity laser having the semiconductor optical element
Inventor: MORI HIROSHI
IPC: H01S5/14
Filed: 2006-09-27
Abstract: It is possible to provide a semiconductor photo-element having an oblique end face of appropriate reflectivity and an oblique end face of low reflectivity and capable of being applied to an EC-LD or SLD and to provide an external resonance laser having the semiconductor photo-element. The semiconductor photo-element includes a waveguide (1G) containing a stripe-shaped active layer formed on a semiconductor substrate (11) and a first end surface (1TL) and a second end surface (1TH) which are cleavage planes parallel to each other. The normal line of the first end face (1TL) and the optical axis of the waveguide (1G) in the vicinity of the first end face (1TL) define a first angle (.phi.L) which is not zero. The normal line of the second end face (1TH) and the optical axis of the waveguide (1G) in the vicinity of the second end face (1TH) define a second angle (.phi.H) which is not zero and different from the first angle (.phi.L). A first spot size (.omega.L) in the width direction of the waveguide (1G) in the vicinity of the first end face (1TL) is different from a second spot size (.omega.H) in the width direction of the waveguide (1G) in the vicinity of the second end face (1TH).
Patent CA-2625521-A1 (CA)
Inventor: EASON JIMMY W
IPC: C22C29/08
Filed: 2006-10-11
Abstract: An earth-boring drill bit having a bit body with a cutting component formed from a tungsten carbide composite material is disclosed. The composite material includes a binder and tungsten carbide crystals comprising sintered pellets. The composite material may be used as a hardfacing on the body and/or cutting elements, or be used to form portions or all of the body and cutting elements. The pellets may be formed with a single mode or multi-modal size distribution of the crystals.