baber/WOPTO huggingface dataset:
Patent AU-2018323950-A1 (AU)
Title: System and method for preparing a soft tissue graft
Inventor: KAM ANDREW
IPC: A61F2/08
Filed: 2018-08-28
Abstract: A system and method for loading a suture construct on a soft tissue graft with a graft assembly. The graft assembly includes a frame with an opening extending between a proximal end and a distal end. The frame has a wall with a first side extending to a first edge and a second side extending to a second edge. A lumen extends between the first side and the second side and a plurality of channels extend through the wall between the first edge and the second edge. The graft assembly also includes a transverse hole extending through the proximal end of the frame and a pin removably inserted into the transverse hole.
Patent AU-2018346511-A1 (AU)
Title: Multivalent antigens stimulating Th1 and Th2
Inventor: SOON-SHIONG PATRICK
IPC: C07K14/47
Filed: 2018-10-04
Abstract: Compositions, methods, and uses of recombinant nucleic acids to elicit Th1- or Th2-biased immune responses in an individual are presented. In some embodiments, the nucleic acid includes a first nucleic acid segment encoding a MHC-II trafficking signal and a second nucleic acid segment encoding a polytope peptide and a Th1-specific polarizing epitope or a Th2-specific polarizing epitope. Optionally, the Th1-specific polarizing epitope or the Th2- specific polarizing epitope is part of the polytope peptide. The recombinant nucleic acid can be inserted in a viral, bacterial, or yeast expression vector so that the recombinant protein encoded by the recombinant nucleic acid can be expressed in an antigen presenting cell of an individual to elicit Th1- or Th2-biased immune response in the individual.
Patent AU-2018350968-A1 (AU)
Title: Method for estimating the effectiveness against rheumatoid arthritis of a T-lymphocyte co-stimulation modulator agent
Inventor: COURTIER ANAÏS
IPC: G01N33/68
Filed: 2018-10-18
Abstract: The present invention concerns a method for estimating the effectiveness of treatment by a modulator agent of the co-stimulation of T-lymphocytes cells in a patient with rheumatoid arthritis and who has had inadequate response to at least one prior biotherapy, consisting of analysing a biological sample of said patient for the expression of a set of biomarkers, the results of which make it possible to determine whether said agent is a treatment which will engender a beneficial response for said patient. The present invention also concerns a system for estimating the effectiveness of said treatment in said patient comprising means for measuring or receiving data concerning the expression of said biomarkers and means for processing these data, configured to estimate the effectiveness of said treatment in the patient. The biomarkers include at least two biomarkers chosen from the group consisting of C4b-Binding Protein (C4BP), C-Reactive Protein (CRP), Cartilage Oligomeric Matrix Protein (COMP), Fibronectine (FN) and Lipopolysaccharide-Binding Protein (LBP).
Patent AU-2018359655-A1 (AU)
Title: Vector construct
Inventor: LØSET GEIR ÅGE
IPC: C12N15/10
Filed: 2018-11-05
Abstract: The present invention provides a vector construct comprising the following components: (i) a sequence encoding a signal peptide which directs proteins into the Tat secretory pathway; and (ii) a sequence encoding a fluorophore fused to a sequence encoding a pVIII phage coat protein. Nucleic acid molecules comprising components (i) and (ii) are also provided, together with phage particles comprising such vectors or nucleic acid molecules and expressing a fluorophore-pVIII fusion protein on the surface. Methods for producing such fluorescent phage particles are also provided.
Patent AU-2018372211-A1 (AU)
Title: Heterocyclic compounds as PRMT5 inhibitors
Inventor: VADIVELU SARAVANAN
IPC: A61K31/4725
Filed: 2018-11-23
Abstract: The compounds of Formula I, Formula Ia, and Formula Ib are described herein along with their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds inhibit PRMT5 and are useful as therpeautic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease and the like.
Patent AU-2018447669-A1 (AU)
Title: Adjustable receptacles
Inventor: HUNT EDWIN R
IPC: B30B9/16
Filed: 2018-10-31
Abstract: An effluent collector includes a filtrate receiving portion having a filtrate opening, and a pressate receiving portion having a pressate opening. The effluent collector includes a diverter barrier adjustably positioned above the pressate receiving portion. The diverter barrier is configured to adjustably direct at least a portion of a flow path toward or away from the pressate receiving portion.
Patent WO-2020047616-A1 (WO)
Inventor: FREEMAN TOM
IPC: E06C7/18
Filed: 2019-09-06
Abstract: La présente invention concerne un système de protection antichute pour une échelle, le système de protection antichute comportant une pluralité d'éléments de barrière pouvant être déplacés entre un état fonctionnel et un état escamoté. Les éléments de barrière coopèrent dans l'état fonctionnel pour constituer une barrière de protection pour au moins une partie de l'échelle, la barrière de protection définie par les éléments de barrière dans l'état fonctionnel aménageant un chemin clos pour un utilisateur de l'échelle.
Patent AU-2019204385-A1 (AU)
Title: A drain grate assembly
Inventor: MAXWELL RONALD
IPC: E06B7/14
Filed: 2019-06-21
Abstract: The present invention relates to a drain grate assembly for a building threshold. The 
assembly includes a drain grate and a sill for receiving and mounting at least one door 
or window. The assembly further includes a holder including portable parts and for 
holding the drain grate and the sill. Advantageously, the same portable part may be 
used for receiving the drain grate, whereas an appropriate portable part can be used to 
form the holder depending upon the width required for the sill.
1/4 
100 
102 104 
Figure 1 
100 
218 \4 224a 224b 216 
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206a 200 222a 2 
206b212a 24 212b 250 
10610 
110 
Figure 2
Patent AU-2019214050-A1 (AU)
Title: Method for suppressing discoloration of external composition containing adenosine phosphate and tranexamic acid
Inventor: OGIHARA MIYOKO
IPC: A61Q19/00
Filed: 2019-01-30
Abstract: The present disclosure provides an external composition containing an adenosine phosphate and/or a salt thereof and a tranexamic acid and/or a salt thereof, the external composition containing a particular chelating agent and/or an organic alkali pH adjuster.
Patent AU-2019232941-A1 (AU)
Title: Wearable medication administration device
Inventor: WALSH JESSICA
IPC: A61M5/20
Filed: 2019-09-20
Abstract: A medication administration device and method of its use is provided. The device has a flexible tube having an administration end, an activation end and a lumen between the ends. An administration assembly is attached to the administration end. An activation assembly is attached to the activation end. A syringe is disposed within the lumen. The syringe contains the medication and has a first end and an opposite second end. A plunger is disposed within the lumen and operatively connected to the first end of the syringe. A rupturable seal is provided to the second end of the syringe, which end is approximate to the administration end. The activation assembly activates the plunger to break the rupturable seal to establish a fluid communication between the second end of the syringe and the administration assembly. Accordingly, transportation of the medication from the syringe to the medication administration assembly through the medication administration end is allowed. WO2015/095095 PCT/US2014/070438
Patent AU-2019236659-A1 (AU)
Title: Animal identification tag
Inventor: TOWNSEND GRANT
IPC: A01K11/00
Filed: 2019-09-25
Abstract: An animal identification ear tag includes a male pin and a female portion that receives the male pin on application of the tag to an animal's ear. The tag includes 5 a single piece moulded panel which extends from a first end at the base of the male pin to a second end where the female portion is arranged. The tag may thus form a closed loop after application to an animal's ear. The female portion includes an opening configured to receive an end of the male pin including a locking shoulder, and a plurality of locking projections positioned around the periphery of the opening 10 and extending towards the centre of the opening, the locking projections being configured to cooperate with the locking shoulder to lock the male pin to the female portion after application of the tag to an animal's ear. (0 (D0 C~Q) coo -.. 00_
Patent AU-2019261666-A1 (AU)
Title: Uses for and article of manufacture including HER2 dimerization inhibitor Pertuzumab
Inventor: ALAVATTAM SREEDHARA
IPC: A61K39/395
Filed: 2019-11-04
Abstract: The present application describes uses for and articles of manufacture including Pertuzumab, a first-in-class HER2 dimerization inhibitor. In particular, the application describes methods for extending progression free survival in a HER2-positive breast cancer patient population; combining two HER2 antibodies to treat HER2-positive cancer without increasing cardiac toxicity; treating early stage HER2-positive breast cancer; treating HER2-positive cancer by co-administering a mixture of Pertuzumab and Trastuzumab from the same intravenous bag; treating HER2-positive metastatic gastric cancer; treating HER2-positive breast cancer with Pertuzumab, Trastuzumab and Vinorelbine; treating HER2-positive breast cancer with Pertuzumab, Trastuzumab and aromatase inhibitor; and treating low HER3 ovarian, primary peritoneal, or fallopian tube cancer. It also describes an article of manufacture comprising a vial with Pertuzumab therein and a package insert providing safety and/or efficacy data thereon; a method of making the article of manufacture; and a method of ensuring safe and effective use of Pertuzumab related thereto. In addition the application describes an intravenous (IV) bag containing a stable mixture of Pertuzumab and Trastuzumab suitable for administration to a cancer patient. 11843590_1 (GHMatters) P96260.AU.3 otog 00 ccl U') (D ( r- 0 V 0- 0 + Qr 0 0D NO) a 0 (s C I Mc0f-ooL tT c C el/n ralu'S96~ + oM N +C
Patent AU-2019274813-A1 (AU)
Title: Treatments
Inventor: HAMPSON IAN
IPC: A61K31/513
Filed: 2019-05-23
Abstract: The present invention concerns pharmaceutical compositions formulated for dermal application comprising a therapeutically effective amount of lopinavir and ritonavir in a pharmaceutically acceptable vehicle and wherein the weight ratio (w/w) of lopinavir: ritonavir is between 9:1 and 18:1. Such compositions are useful for treating, or preventing, skin cancers and premalignant dermal conditions.
Patent AU-2019276173-A1 (AU)
Title: Immunogenic product comprising IL-4 and/or IL-13 for treating disorders associated with aberrant IL-4 and/or IL 13 expression or activity
Inventor: GROUARD-VOGEL GÉRALDINE
IPC: A61P37/08
Filed: 2019-05-29
Abstract: The present invention relates to an immunogenic product comprising a cytokine conjugated with a carrier protein, wherein the cytokine is selected from the group comprising IL-4, IL-13 and mixtures thereof, and wherein the carrier protein is CRM197. The present invention further relates to a method for manufacturing the immunogenic product of the invention. The present invention also relates to the therapeutic use of the immunogenic product of the invention for treating an inflammatory disorder associated with aberrant IL-4 and/or IL-13 expression or activity.
Patent AU-2019282825-A1 (AU)
Title: Multimeric proteins for detecting a carbohydrate and/or treating a siglec-mediated disorder
Inventor: PENG LI
IPC: A61P35/00
Filed: 2019-06-07
Abstract: The invention relates generally to polypeptides comprising a lectin domain, multimeric proteins comprising the polypeptides, and use of the polypeptides or multimeric proteins in the detection of a carbohydrate (
Patent AU-2019283460-A1 (AU)
Title: Improvements in, or relating to, applicators
Inventor: CALDER DAVID BAIN
IPC: A61D7/00
Filed: 2019-06-06
Abstract: Disclosed is an applicator, and a handle for an applicator. The applicator has at least one barrel and a piston moveable within the at least one barrel to stroke between a variable first position and a second position. In use, movement of the piston towards the first position can draw a first fluid into the barrel, and movement of the piston towards the second position can force the first fluid out of the barrel. The barrel has at least one fluid inlet valve to allow the fluid to flow into the at least one barrel at least under action of the piston, and at least one fluid outlet valve to allow the first fluid to flow out of the at least one barrel at least under action of the piston. A handle has a piston actuator assembly, housed at least in part within a body of the handle, operable to move the piston towards the second position to dispense the first fluid from the applicator. The piston actuator has a first actuating component driven by a user operated handle to pivot and tension a first biasing component, a second actuating component held in position against a force of the first biasing component, a first trigger component that holds the second actuating component in place until a required force is reached by the first biasing component, or a second trigger component releases the first trigger component. The second actuating component is then released and driven by the force of the first biasing component to in turn drive the piston toward the second position. The movement of the first actuating component is independent of the stroke of the piston.
Patent AU-2019286654-A1 (AU)
Title: System and method for monitoring process water treated with a biocide using an oxygen sensor
Inventor: BARAK AYALA
IPC: C02F1/50
Filed: 2019-06-03
Abstract: A system and method for monitoring process water treated with a biocide is provided. The system includes a biocide feeding unit and a dissolved oxygen sensor. The dissolved oxygen sensor works in two modes, a biocide feeding mode and a background mode, and alerts an operator when the dissolved oxygen value indicates a fault in the system. A drop in dissolved oxygen during feeding can indicate faulty production of biocide or biocide degradation, both of which can lead to unwanted disinfection by-products.
Patent AU-2019293378-A1 (AU)
Title: Lubricating oil compositions
Inventor: PALAZZOTTO JOHN D
IPC: C10M141/06
Filed: 2019-06-24
Abstract: Disclosed is a natural gas engine lubricating oil composition which comprises: (a) a major amount of an oil of lubricating viscosity having a kinematic, (b) greater than about 2 wt. % but less than about 4 wt. %, based on the total weight of the natural gas engine lubricating oil composition, of one or more phenolic antioxidants, (c) about 0.1 to about 1 wt. %, based on the total weight of the natural gas engine lubricating oil composition, of one or more aminic antioxidants, (d) one or more metal dithiophosphates, and (e) one or more alkali metal or alkali earth metal phenate detergents having a TBN of about 150 to about 250 on an oil free basis, wherein the one or more alkali metal or alkali earth metal phenate detergents provide at least about 0.10 wt. % of alkali metal or alkali earth metal to the natural gas engine lubricating oil composition.
Patent AU-2019300203-A1 (AU)
Title: Ophthalmic compositions containing a nitric oxide releasing prostamide
Inventor: PILOTAZ FRÉDÉRIC
IPC: A61K47/14
Filed: 2019-07-10
Abstract: The present invention provides aqueous ophthalmic compositions in the form of solution comprising hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester and macrogol 15 hydroxystearate as the only solubilizing agent, and a method for their preparation.
Patent AU-2019320631-A1 (AU)
Title: Water electrolysis apparatus
Inventor: SUZUKI KEITA
IPC: C25B9/00
Filed: 2019-08-08
Abstract: Control of the aperture of an oxygen pressure control valve (21) comprises: a first feedback control for controlling, on the basis of the internal tank pressure detected by a first internal tank pressure-detecting unit (22), the aperture of the oxygen pressure control valve (21) so that the difference between the internal tank pressure and a predetermined target pressure is reduced; and a first feedforward control for controlling the aperture of the oxygen pressure control valve (21) on the basis of the electric current detected by an electric current-detecting unit (15). Control of the aperture of a hydrogen pressure control valve (26) comprises: a second feedback control for controlling, on the basis of the internal tank pressure detected by a second internal tank pressure-detecting unit (27), the aperture of the hydrogen pressure control valve (26) so that the difference between the internal tank pressure and the target pressure is reduced; and a second feedforward control for controlling the aperture of the hydrogen pressure control valve (26) on the basis of the electric current detected by th electric current-detecting unit (15).
Patent AU-2019327667-A1 (AU)
Title: Data deduplication and data merging
Inventor: MORGAN PHILIP JOHN BOYD
IPC: G06F16/483
Filed: 2019-08-27
Abstract: A system (100) for data deduplication and data merging. The system receives attributes associated with data sets from a plurality of sources (102). The system includes a data store (104) that stores: original attributes (106) associated with existing data sets, the attributes including an identifier associated with each data set; merged sets of attributes (108); and an index associating the original attributes and the merged sets of attributes. A processing device (112) is configured to: receive new attributes (114) associated with a data set, wherein the new attributes include a new identifier; and compare the new attributes (114) with the merged sets of attributes to determine a common identifier. Based on the new attributes, the processor updates a set of merged attributes associated with the common identifier, and stores a new index record, or updated index record, that associates the new attributes with the updated set of merged attributes associated with the common identifier.
Patent AU-2019361779-A1 (AU)
Title: A series of compounds for treatment of skin diseases and other conditions
Inventor: NANDY SANDIP K
IPC: C07C59/68
Filed: 2019-10-13
Abstract: Compounds and methods related to the prevention and treatment of diseases and conditions, some of which are facilitated by melanogenesis are disclosed. Specifically, the present subject matter includes a series of compounds and compositions and their use for anti-melanogenic and antioxidant activity. This subject matter also includes the treatment of skin disorder due to acne vulgaris and related inflammatory and post inflammatory hyperpigmentation. Methods for synthesizing contemplated compounds are also disclosed.
Patent AU-2019369917-A1 (AU)
Title: Use of cysteine or salt thereof for cryoprotecting lactic acid bacteria
Inventor: SHIN DONG JOO
IPC: C12N1/04
Filed: 2019-10-28
Abstract: The present application relates to use of cysteine or a salt thereof for the protection, growth acceleration and/or stability improvement of lactic acid bacteria.
Patent AU-2019382919-A1 (AU)
Title: Production of immobilised bacteriophage
Inventor: MICHAEL MATTEY
IPC: B01J19/08
Filed: 2019-11-22
Abstract: Bacteriophage is covalently attached to a substrate by (a) combining (i) substrate with (ii) bacteriophage, wherein prior to or during the combining (i) or (ii) or both (i) and (ii) are activated, and wherein (b) during the combining the bacteriophage is contained within a liquid droplet of average diameter 150 microns or less.
Patent AU-2019387368-A1 (AU)
Title: Platelets as delivery agents
Inventor: MOSKOWITZ KEITH ANDREW
IPC: C07K16/28
Filed: 2019-11-27
Abstract: In some embodiments provided herein is a method of preparing cargo-loaded platelets, comprising: treating platelets with a cargo and with a loading buffer comprising a salt, a base, a loading agent, and optionally ethanol, to form the cargo-loaded platelets.
Patent AU-2019411483-A1 (AU)
Title: A nutritional composition comprising 2'-Fucosyllactose (2' FL) to improve the gastrointestinal barrier
Inventor: GARCIA-RODENAS CLARALUCIA
IPC: A23L33/21
Filed: 2019-12-11
Abstract: The present invention relates to nutritional compositions comprising 2'- Fucosyllactose (2'FL) for use in improving the gastrointestinal barrier. In particular, the present invention relates to improving gastrointestinal barrier in an infant, a young child or children aged above 3 years to 8 years.
Patent AU-2019425998-A1 (AU)
Title: Energy-saving and consumption-reducing belt conveyor
Inventor: PENG SUHUA
IPC: B65G39/12
Filed: 2019-07-17
Abstract: A belt conveyor, comprising a rack, and a drive roller, a redirection roller and supporting rollers which are supported on the rack, wherein the supporting rollers are divided into an upper supporting roller (1) and a lower supporting roller (2); an upward moving section and a downward moving section of the belt are supported by the upper supporting roller (1) and the lower supporting roll (2) respectively; the upper supporting roller (1) is installed on a first support, and the lower supporting roller (2) is installed on a second support; the first support comprises a first cross beam (4) and a plurality of first supporting racks (5); and the second support comprises a second cross beam (6) and second supporting racks (7). The first supporting racks (5) are respectively arranged alternately on the first cross beam (4), and the second supporting racks (7) are respectively arranged alternately on the second cross beam (6). The present belt conveyor may achieve three points on different dimension lines forming a face, thereby increasing effective contact points, enlarging a touch surface, reducing the weight of the supporting rollers, reducing friction, and reducing damage to the supporting rollers.
Patent AU-2019440748-A1 (AU)
Title: Method, device and apparatus for controlling touch operation mode, and storage medium
Inventor: GU YICHANG
IPC: G06F3/041
Filed: 2019-11-26
Abstract: The present invention relates to the technical field of computers. Disclosed are a method, device and apparatus for controlling a touch operation mode, and a storage medium. The method comprises: responding to a received mode trigger operation; selecting a touch operation mode corresponding to the mode trigger operation as a triggered initial touch operation mode; monitoring an operation duration in the initial touch operation mode; and determining and controlling execution of a current touch operation mode according to the operation duration.
Patent WO-2021113920-A1 (WO)
Inventor: GUO ZAIPING
IPC: H01M4/1395
Filed: 2020-12-11
Abstract: Disclosed is a method of fabricating an anode for a lithium-ion battery, comprising the steps of: mixing a silicon/graphite/carbon material, one or more linear polymers, one or more conductive polymers, one or more self-healing polymers, and one or more rubber polymers to produce a slurry; coating the slurry onto a metallic member; and drying the metallic member with coated slurry to form the anode. Also disclosed is an anode and a lithium-ion battery. Also disclosed is a multi-functional polymer binder including one or more linear polymers, one or more conductive polymers, one or more self-healing polymers, and one or more rubber polymers.