baber/WOPTO huggingface dataset:
Patent UA-117963-C2 (UA)
Title: Passive depressurisation system for pressurised receptacles
Inventor: LABORDA RAMI ARNALDO
IPC: G21D3/06
Filed: 2014-05-05
Abstract: The invention relates to a depressurisation system characterised in that it comprises a main valve (8) provided with a pneumatic actuator having an opening spring (10), which valve can be connected by one end to a pressurised receptacle (1) housing a gas inside, and connected to the atmosphere by the other end, said opening spring (10) defining a predetermined mechanical pressure, such that when the pressure inside the pressurised receptacle (1) is higher than the predetermined mechanical pressure the main valve (8) is closed, and when the pressure inside the pressurised receptacle (1) is lower than the predetermined mechanical pressure the main valve (8) is open, allowing the gas of the pressurised receptacle (1) to be released into the atmosphere. The system does not require an external energy supply, permitting the system to adequately perform its function, even in accident scenarios with a total loss of electrical energy.
Patent UA-119573-C2 (UA)
Title: Compositions
Inventor: BENCIC NENAD
Filed: 2015-10-01
Abstract: Disclosed herein is an aqueous solution comprising from 80 mg A/mL to 400 mg A/mL of a sulfomethylated polymyxin and a cartridge containing the same. In addition it is disclosed an aqueous solution for use in therapy.
Patent UA-118525-C2 (UA)
Title: Спосіб діагностики ускладненого перебігу хронічної серцевої недостатності у хворих з поєднаним перебігом ішемічної хвороби серця й ожиріння
Filed: 2018-01-31
Abstract: Винахід належить до медицини, а саме до кардіології, терапії та ендокринології, та може бути використаний для діагностики ускладненого перебігу хронічної серцевої недостатності у хворих з поєднаним перебігом ішемічної хвороби серця й ожиріння за поліморфізмами генів (ангіотензиногена, фактору некрозу пухлин-п). Cпосіб діагностики ускладненого перебігу хронічної серцевої недостатності включає оцінку рівнів маркерів ризику в сироватці крові у хворих з поєднаним перебігом ішемічної хвороби серця й ожиріння, при якому проводять дослідження алельних поліморфізмів Met235Thr гена ангіотензинтогена, G-308A гена фактора некрозу пухлин-п методом полімеразної ланцюгової реакції з електрофоретичної детекцією результатів з використанням наборів реактивів «SNP-ЕКСПРЕС», визначають рівень інсуліну крові натщесерце методом імуноферментного аналізу, вимірюють індекс маси тіла, кінцевий систолічний об'єм і фракцію викиду з наступним розрахунком за формулою: ризик серцево-судинних ускладнень = 1/(1+Exp(-Y)), де Y = інсулін × 2,18 + індекс маси тіла × 3,04 + кінцевий систолічний об'єм × 2,97 + фракція викиду × 1,64 + генотип Т/Т поліморфного локусу М235Т гена ангіотензиногена × 1,23 - генотип А/А поліморфного локусу G-308A гена фактора некрозу пухлин-п × 2,18 - 2,88; змінні, що входять до рівняння, кодують як 1 за наступних умов: інсулін > 19,76 мкОД/мл; індекс маси тіла > 27,6 кг/м2; кінцевий систолічний об'єм > 186 мл; фракція викиду < 33 %; наявність генотипу Т/Т поліморфного локусу М235Т гена ангіотензиногена та генотипу А/А поліморфного локусу G-308A гена фактора некрозу пухлин-п, якщо умови не виконуються, змінні кодують 0, та при значенні ризику серцево-судинних ускладнень ≥ 70 % діагностують ускладнений перебіг хронічної серцевої недостатності.
Patent UA-125747-C2 (UA)
Title: Methods and compositions for treating conditions associated with an abnormal inflammatory responses
Inventor: GLICK GARY D
Filed: 2016-09-01
Abstract: This disclosure features chemical entities (e.g., a compound exhibiting activity as a mitochondrial uncoupling agent or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof; e.g., a compound, such as niclosamide or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof; e.g., a compound, such as a niclosamide analog, or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof) that are useful, e.g., for treating one or more symptoms of a pathology characterized by an abnormal inflammatory response (e.g., inflammatory bowel diseases) in a subject (e.g., a human). This disclosure also features compositions as well as other methods of using and making the same.
Patent UA-121899-C2 (UA)
Title: ЗАСТОСУВАННЯ ГІДРОБРОМІДУ 2-[(5,6-ДИГІДРО-4Н-[1,3]ТІАЗИН-2-ІЛ)-ФЕНІЛАМІНО]-1-(4<sup>1</sup>-МЕТОКСИФЕНІЛ)-ЕТАНОНУ ЯКІСПОЛУКИ, ЩО ПРОЯВЛЯЄ АНАЛГЕТИЧНУ АКТИВНІСТЬ
Filed: 2018-04-17
Abstract: Гідробромід 2-[(5,6-дигідро-4Н-[1,3]тіазин-2-іл)-феніламіно]-1-(41-метоксифеніл)-етанону, що проявляє аналгетичну активність (FT000183). Винахід належить до фармацевтичної хімії та медицини. Показано, що на моделі "гаряча пластина" заявлена сполука в дозах 1/10 від LD50, 25 мг/кг та еквімолярній ED50 диклофенаку натрію переважає препарат порівняння -диклофенак натрію та складає +304,0 %, +225,0 % і 120,2 % зміни латентного періоду реакції відповідно. В той же час як у диклофенаку натрію ці показники становлять лише +137,2 % та 109,09 % відповідно. Таким чином, запропонована біологічно активна сполука, яка може стати основою для розробки нового аналгетичного засобу з протизапальною дією.
Patent UA-120015-C2 (UA)
Title: Спосіб виробництва кисловершкового масла
Filed: 2018-06-14
Abstract: Винахід стосується способу виробництва кисловершкового масла, який передбачає пастеризацію вершків, охолодження до температури дозрівання, внесення бактеріального препарату, дозрівання, сколочування, причому до складу бактеріального препарату входять мезофільні культури видів Lactococcus lactis subsp lactis та Lactococcus lactis subsp diacetylactis, попередньо активований бактеріальний препарат вносять у кількості 10 г/т, для дозрівання застосовують ступінчатий температурний режим для значень йодного числа молочного жиру 29,1-34,5 за температури 8-9 °С протягом 2 год., далі за температури 21-22 °С протягом 6 год. і за температури 13-14 °С протягом 7-10 год., а для значень йодного числа молочного жиру 34,6-40,1 за температури 21-22 °С протягом 6 год., далі за температури 13-14 °С протягом 4 год. і за температури 8-9 °С протягом 6-9 год.
Patent UA-120896-C2 (UA)
Title: Фармацевтична композиція у формі оральної суспензії протимікробної та гепатопротекторної дії
Filed: 2018-07-04
Abstract: Винахід належить до фармації та медицини, зокрема до фармацевтичних композицій, що складаються з компонентів синтетичного та рослинного походження, виконаних переважно у формі оральної суспензії та виявляють протимікробну та гепатопротекторну дію.
Patent UA-121528-C2 (UA)
Title: N-АРИЛАЛКІЛ-4-МЕТИЛ-2,2-ДІОКСО-1H-2<font face="Symbol">l<sup>6</sup></font>,1-БЕНЗОТІАЗИН-3-КАРБОКСАМІДИ, ЯКІ ВИЯВЛЯЮТЬ АНАЛГЕТИЧНУ ТА ПРОТИЗАПАЛЬНУ АКТИВНІСТЬ
Filed: 2019-01-10
Abstract: Винахід належить до хіміко-фармацевтичної промисловості і стосується біологічно активних речовин, зокрема похідних бензотіазинкарбонових кислот, а саме N-арилалкіл-4-метил-2,2-діоксо-1H-2λ6,1-бензотіазин-3-карбоксамідів, які виявляють аналгетичну та протизапальну активність. 8
Patent UA-127872-C2 (UA)
Title: Macrocyclic compound and use thereof
Inventor: MATSUMOTO SHIGEMITSU
Filed: 2019-12-04
Abstract: A compound represented by the following formula (I): wherein each symbol in the formula is as described herein or a salt thereof has an NRF2 activating activity, and is expected to be useful as a preventive or therapeutic agent for diseases associated with oxidative stress, in particular, hepatic disease (for example, non-alcoholic steatohepatitis (NASH)), cardiovascular disease (for example, heart failure or pulmonary arterial hypertension), lung disease (for example, chronic obstructive pulmonary disease (COPD)), kidney disease (for example, chronic kidney disease (CKD) or acute kidney injury (AKI)), central nervous system disease (for example, Parkinson's disease), mitochondrial disease (for example, Friedreich motor ataxia, mitochondrial myopathy), inflammatory disease (for example, multiple sclerosis (MS), inflammatory bowel disease (IBD)), sickle cell disease, cancer, or the like.
Patent UA-73990-C2 (UA)
Title: Substituted bicyclic derivatives for the treatment of abnormal cells growth
Inventor: KATH JOHN CHARLES
IPC: A61P35/00
Filed: 2001-06-14
Abstract: The invention relates to compounds of the formula (1) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R3, R4, R5, R11, m and p are as defined herein. The invention also relates to methods of treating abnormal cell growth m mammals by administering the compounds of formula (1) and to pharmaceutical compositions for treating such disorders which contain the compounds of formula (1). The invention also relates to methods of preparing the compounds of formula (1).
Patent UA-87958-C2 (UA)
Title: Ifnar2 mutants, their production and use
Inventor: SCHREIBER GIDEON
IPC: C07K19/00
Filed: 2002-12-31
Abstract: The present invention relates to mutant polypeptides of the beta chain of the type I IFN receptor (IFNAR2 mutant) with enhanced affinity for interferon-beta as compared to the wild type protein for prolonging the effect of IFN-beta in vivo and to use of said mutant polypeptides for the preparation of medicinal agent for the treatment of multiple sclerosis, rheumatoid arthritis, myasthenia gravis, diabetes, ulcerative colitis and lupus, chronic granulomatous disease, condyloma acuminatum, juvenile laryngeal papillomatosis, hepatitis A or chronic infection with hepatitis B and C viruses, hairy cell leukemia, Kaposi's sarcoma, multiple myeloma, chronic myelogenous leukemia, non-Hodgkins's lymphom or melanoma.
Patent UA-76023-C2 (UA)
Title: Method for regeneration of alloys in shock waves
Inventor: DIDYK ROSTYSLAV PETROVYCH
IPC: C22B34/00
Filed: 2004-08-16
Abstract: Method for regeneration of tungsten cobalt alloy, including working alloys to be renerated by shock waves in the presence of vacuum-treated medium with the parameter of rarefaction 10-2-10-3 mm Hg.
Patent UA-77768-C2 (UA)
Title: Cathepsin cysteine protease inhibitors, pharmaceutical composition based thereon and a process for preparation thereof
Inventor: BAYLY CHRISTOPHER I
IPC: C07D213/89
Filed: 2003-02-28
Abstract: This invention relates to a novel class of compounds that are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
Patent DE-10006852-C5 (DE)
Title: Verfahren und Vorrichtung zum Fügen von Werkstückteilen mittels eines Energiestrahls, insbesondere Laserstrahls
Inventor: HASCHKE IGOR
IPC: B23K26/02
Filed: 2000-02-16
Granted: 2004-08-26
Abstract: Verfahren zum Fügen von Werkstückteilen mittels eines Energiestrahls, insbesondere Laserstrahls, unter Verwendung eines Zusatzwerkstoffes, der in Form eines Drahtes mittels einer Drahtzuführungseinrichtung zugeführt wird, wobei der Draht auch als mechanisches Tastelement verwendet und die am Energiestrahl abschmelzende Drahtspitze kraftschlüssig entlang der Werkstückoberfläche geführt wird, dadurch gekennzeichnet, dass auf einer Vorschubbahn einer Führungsmaschine die Kontur eines von den zu verbindenden Werkstückteilen (7, 8; 9, 10) definierten Stoßes über die Drahtspitze im Schmelzbadrand angetastet wird, wobei  a) der Energiestrahl (1) mit einer Einrichtung fokussiert wird, die mit der Drahtzuführungseinrichtung automatisch mitbewegt wird, wobei die Drahtzuführungseinrichtung relativ zu der Einrichtung zur Fokussierung des Energiestrahls bewegbar ist und der Bezugspunkt für die Nachführung des Energiestrahlfokus am Schmelzbadrand liegt, oder  b) die am Energiestrahl (1) abschmelzende Drahtspitze (4) kraftschlüssig entlang einer seitlichen Führungsfläche des von den zu verbindenden Werkstückteilen (7, 8; 9, 10) gebildeten Verbindungsstoßes geführt wird, wobei der Energiestrahl (1) und die...
Patent DE-102011078830-C5 (DE)
Title: Gebäudetür
Inventor: LIEB HANS-DIETER
IPC: E05F15/70
Filed: 2011-07-07
Granted: 2020-04-02
Abstract: Gebäudetür, mit- einem Türrahmen,- einem bewegbar an dem Türrahmen angeordneten Türflügel,- einer Antriebsvorrichtung zum elektromotorischen Verstellen des Türflügels relativ zu dem Türrahmen und- einem Steuergerät zum Steuern der Antriebsvorrichtung,- einem mechanischen Endanschlag,wobei der Türflügel bei einem Öffnen über einen Verstellweg von einer geschlossenen Stellung in eine Endstellung, in der der Türflügel geöffnet ist, überführbar ist, wobei der mechanische Endanschlag einen maximalen Öffnungsweg des Türflügels begrenzt,dadurch gekennzeichnet,dass der Verstellweg (α, α') zwischen der geschlossenen Stellung (Pzu) und der Endstellung (PEND, PEND') kleiner ist als der maximale Öffnungsweg und das Steuergerät (4) ausgebildet ist, die Endstellung (PEND, PEND') zu speichern und die Antriebsvorrichtung (2) derart anzusteuern, dass der Türflügel (10) beim Öffnen nicht über die Endstellung (PEND, PEND') hinaus bewegbar ist, wobei bei einem manuellen Öffnen des Türflügels (10) das Steuergerät (4) die Antriebsvorrichtung (2) bei Erreichen der gespeicherten Endstellung (PEND, PEND') zum Blockieren einer Bewegung des Türflügels (10) über die Endstellung (PEND, PEND') hinaus ansteuert, wobei das Steuergerät (4) ausgebildet ist, mehrere Endstellungen (PEND, PEND') zu speichern, wobei das Steuergerät (4) zum Einstellen unterschiedlicher Endstellungen (PEND, PEND') schaltbar ist und ausgebildet ist, ein manuelles Führen des Türflügels (10) aus einer ersten gespeicherten Endstellung (PEND) in eine zweite gespeicherte Endstellung (PEND') als Befehl zum Schalten von der ersten Endstellung (PEND) zur zweiten Endstellung (PEND') zu erkennen.
Patent DK-10987-D0 (DK)
Inventor: HOLLESEN BASSE SVEN AAGE
IPC: A47C1/032
Filed: 1987-01-09
Abstract: PCT No. PCT/DK88/00002 Sec. 371 Date Aug. 26, 1988 Sec. 102(e) Date Aug. 26, 1988 PCT Filed Jan. 7, 1988 PCT Pub. No. WO88/04902 PCT Pub. Date Jul. 14, 1988.A chair comprises a seat (6), a back (7) and a frame (2, 3, 4, 5). In order to give the user a comfortable opportunity to change his position during the use of the chair, the positions of both the chair (6) and the back (7) are readjustable with respect to the frame. The angular position of the seat is readjustable from a first position to a more backward inclined position and the back (7) is readjustable from a first position to a more backwardly inclined position. The back (7) is during the readjustment lowerable with respect to the seat (6) in order to avoid movements between the body and the clothes of the user during the readjustment of the chair.
Patent DK-130585-D0 (DK)
Inventor: RUOFF-SCHAEFER RUDOLF
IPC: F16L59/135
Filed: 1985-03-22
Abstract: An insulating material for pipes which consists of a layer of insulation and a sleeve that surrounds the pipe with the insulating layer being asymmetrically arranged relative to the pipe which is to be insulated.
Patent DK-139389-D0 (DK)
Inventor: LOTZE MARION
IPC: C04B41/88
Filed: 1989-03-21
Abstract: For dishwasher-resistant decorations on tableware consisting of silicate materials, bright rare metal preparations are used which consist of one or more organo-compounds of rare metals, an organic carrier and a flux of organic metal compounds, the flux containing an organic silicon compound having three and/or four hydrolysable groups on the silicon atom in quantities of 0.1 to 4 mol of silicon per mol of rare metal.
Patent DK-298484-D0 (DK)
Inventor: SOELL ERNST
IPC: E06C7/18
Filed: 1984-06-19
Abstract: 1. A device for shifting a safety means for climbers from a first climbing path (4) to a second climbing path (5), said safety means comprising a slide (8) moving along a longitudinal guide path (2) and having a releasable lock against downward movement, characterized in that a short portion (1) of the longitudinal guide path (2) is slidable in parallel along a transverse guide path (3) between the first climbing path (4) and the second climbing path (5).
Patent DK-393288-D0 (DK)
Inventor: ANTONIADES HARRY N
IPC: A61K35/14
Filed: 1988-07-14
Abstract: Healing an external wound or regenerating bone of a mammal by administering to the mammal a composition containing purified platelet-derived growth factor and purified insulin-like growth factor.
Patent DK-409184-D0 (DK)
Inventor: HEDENBERG GUNNAR
IPC: A21B1/22
Filed: 1984-08-28
Abstract: The preparation starts from dry and/or wet ingredients. The apparatus comprises at least one mixing - kneading - and heat treatment station (13, 14). The object of the invention is to provide a baking apparatus by means of which food products such as bread can be produced without any real manual work involved, without soiling vessels and utensils and which can be programmed so that a correct fermentation process under the right temperature conditions is provided. This has been achieved by the fact that in the mixing- and kneading station (13) there are arranged means (11) for holding and/or displacing at least one flexible vessel (12). e.g. a plastic bag, which contains or is intended to receive said ingredients, and that the mixing- and kneading means (87, 88) of the first station are arranged to mix the ingredients and work the mass located in the vessel (12) by outer mechanic agitation of the vessel.
Patent DK-413488-D0 (DK)
Inventor: BROZE JR GEORGE JOHN
IPC: C07K14/745
Filed: 1988-07-22
Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
Patent DK-420285-D0 (DK)
Inventor: HOEIER ERIK
IPC: A23C19/028
Filed: 1985-09-16
Abstract: In a process for producing cheese from milk, an inactive milk-clotting enzyme and optionally chymosin or another suitable proteolytic enzyme is added to the milk, optionally simultaneously with or after adding a starter culture, to form a curd, at least part of the inactive enzyme is activated, and the resulting curd is converted to the ripened cheese. The milk employed is preferably concentrated milk, and the inactive milk-clotting enzyme is preferably prochymosin.
Patent DK-457688-D0 (DK)
Inventor: LAKE HAROLD
IPC: H05K3/46
Filed: 1988-08-16
Abstract: A process for making additive multilayer circuit boards wherein an insulating film (16 preferred a photo-processible film) is bonded to a pre-existing multilayer structure and selected areas of the insulating film are removed down to underlying metal sites (14) for electroless plating. All of the apertures in the insulating film are then electrolessly plated full of metal flush to the upper surface. Additional patterned composites are applied and plated up as desired to create blind vias and new conductor patterns layer by layer. In a preferred embodiment the insulating film (28) supports a patterned conductive metal foil (30) and is bonded foil pattern side down to the substrate. In an alternate process a foil clad composite is bonded to an existing substrate foil side up. The insulating layer is selectively etched through windows photoetched in the foil layer. The voids in the insulator layer expose copper sites on the underlying composite. The voids are plated full of metal to form vias and the foil layer is photoetched to make a conductor pattern. The process is repeated to make a multilayer PWB.
Patent DK-593886-D0 (DK)
Inventor: BENDER PAUL ELLIOT
IPC: C07D233/84
Filed: 1986-12-10
Abstract: This invention relates to 4,5-diaryl-2-(substituted)imidazoles or pharmaceutically acceptable salts thereof, for use in inhibiting the 5-lipoxygenase pathway of arachidonic acid metabolism, to methods for their preparation and to pharmaceutical compositions containing them.
Patent DK-623884-D0 (DK)
Inventor: WUHRMANN JUAN CARLOS
IPC: C11D3/18
Filed: 1984-12-21
Abstract: Foam regulators particularly suitable for use in surfactant-containing compositions, comprising a mixture of paraffin hydrocarbons and hydrophobic silica, preferably admixed with a carrier.
Patent NO-883605-D0 (NO)
Inventor: FISHER ABRAHAM
IPC: A61P25/28
Filed: 1988-08-12
Abstract: The (+)-cis-, (-)-cis-, (+)-trans- and (-)-trans- forms of 2-methylspiro(1,3-oxathiolan-5,3 min )quinuclidine <CHEM> are prepared by optical resolution of each of the (+/-)-cis- and (+/-)-trans-isomers. These compounds find application in treating diseases of the central nervous system in mammals, especially diseases due to a deficiency in the central cholinergic system. Biological tests indicate that the (-)-cis-form, as well as the (+/-)-cis-isomer, shows particular promise for treating senile dementia of Alzheimer's type.
Patent NO-885208-D0 (NO)
Inventor: TIMELL HANS
IPC: B65H67/06
Filed: 1988-11-23
Abstract: PCT No. PCT/SE88/00031 Sec. 371 Date Sep. 5, 1989 Sec. 102(e) Date Sep. 5, 1989 PCT Filed Feb. 1, 1988 PCT Pub. No. WO88/07494 PCT Pub. Date Oct. 6, 1988.The disclosure relates to an apparatus for the arrangement and preparation of cores (13) intended for use as reel cores in papermaking in a number of stations with tools for carrying out a number of working operations in and/or on each one of the ends of the cores (13), the stations being disposed in side-by-side relationship and having opening and closing grippers (16) for fixedly retaining the core (13) which is to be arranged and prepared, in each respective station during the execution of one or more working operations therein, the opening and closing grippers (16) being disposed on the one, free end of an arm (17) which is located at each end of the core (13) and which, at the opposite end in relation to the opening and closing grippers (16), is pivotal about a shaft (18) located beside the station. Furthermore, the arms (17), with the opening and closing grippers (16), are interconnected for simultaneous pivoting about the shaft (18) for transferring a core (13) substantially non-rotatably fixedly held by the grippers (16), from the above-mentioned station to the immediately subsequent station, in which open grippers (16) are arranged to be closed about the core (13) and thereby grasp and fixedly retain the core (13) in an orientationally controlled position before the preceding grippers (16) are opened for release of the core (13).
Patent NO-885345-D0 (NO)
Inventor: ERIKSSON BROR
IPC: B27G13/00
Filed: 1988-11-30
Abstract: The invention relates to a debarking means for rotation ring type barking machines, and of the type comprising a plurality of swinging arms (1) yieldably engaging the circumference of an unbarked log and each formed at its free end with a seat (4) for a debarking means (2) detachably mounted by means of a bolt connection (3). The debarking means has a leading edge (7) serving as a cutting edge and a trailing support edge or surface (8) adapted to engage a shoulder (5) on the seat (4) to prevent turning of said debarking means relative to the arm. The support edge (8) extends obliquely in relation to the cutting edge (7), more particularly along the entire width of the debarking means and between two side edges of said means which are of different length.
Patent NO-885478-D0 (NO)
Inventor: WIGGLESWORTH PAUL
IPC: B01F3/08
Filed: 1988-12-09
Abstract: An apparatus (10) for making a post-foaming gel comprising, a first cylinder (12) having a chamber (14) and a slidable piston (16) separating the chamber (14) into a first compartment (18) to receive a gel base and a second compartment (20), a second cylinder (22) having a chamber (24) and a slidable piston (26) separating the chamber (24) into a first compartment (28) to receive the gel base and a second compartment (30), a conduit (38, 40) connecting the first compartments (18, 28) of the first and second cylinders (12, 22), a device (72) for reciprocating the pistons in the first and second cylinders (12, 22) to cycle the gel base through the conduit (38, 40) between the first compartments (18, 28) of the first and second cylinders (12, 22), and a device (42) for introducing a foaming agent to the gel base while it is being cycled between the cylinders (12, 22).