baber/WOPTO huggingface dataset:
Patent CA-2263957-A1 (CA)
Title: Diarylmethyl piperazine derivatives as delta opioid agonists
Inventor: MIDDLETON DONALD STUART
IPC: A61K31/00
Filed: 1999-03-03
Abstract: Compounds of the formula (I) - shown below - are described.     (see fig. I) The compounds are useful in the manufacture of a pharmaceutical composition for preventing or treating inflammatory diseases such as arthritis, psoriasis, asthma, or inflammatory bowel disease, disorders of respiratory function, gastro-intestinal disorders such as functional bowel disease, functional GI disorders such as irritable bowel syndrome, functional diarrhoea, functional distension, functional pain, non-ulcerogenic dyspepsia or others associated with disorders of motility or secretion, urogenital tract disorders such as incontinence, as analgesics for treating pain including non-somatic pain, or as immunosuppressants to prevent rejection in organ transplant and skin graft.
Patent CA-2265304-A1 (CA)
Inventor: WYNNE-EDWARDS ROBIN ALEXANDER
IPC: G01N27/12
Filed: 1999-03-15
Abstract: A method and system for determining concentrations of gases in an unknown gas mixture using stored data voltage profiles obtained by measuring such profiles of known gases.
Patent CA-2265318-A1 (CA)
Title: Hydroformylation of olefin feeds containing dienes
Inventor: DRENT EIT
IPC: C07B41/02
Filed: 1999-03-15
Abstract: A process for the hydroformylation of a feed comprising compounds having a single ethylenically unsaturated group by reaction thereof in the liquid phase with carbon monoxide and hydrogen in the presence of a catalyst system comprising a) a source of palladium cations; b) a source of anions; c) a source of at least one bidentate ligands of the formula R1R2M1RM2R3R4 (I) wherein M1 and M2 independently represent a phosphorus, arsenic or antimony atom, R represents a bivalent bridging group containing from 1-4 atoms in the bridge, R1 and R2 independently represent a substituted or unsubstituted hydrocarbyl group, or together represent a bivalent substituted or unsubstituted cyclic group whereby the two free valencies are linked to M1, and R3 and R4 independently represent a substituted or unsubstituted hydrocarbyl group, or together represent a bivalent substituted or unsubstituted cyclic group whereby the two free valencies are linked to M2; and d) a source of halide chosen from the group of chloride, iodide and bromide and mixtures thereof; characterized in that the ethylenically unsaturated feed comprises one or more dienes and/or further multiply unsaturated alkenes to an amount of 0.005 - 5 wt% based on the total amount of ethylenically unsaturated compounds in the feed, and in that component b) of the catalyst system comprises a source of anions of an acid having a pKa value, measured in aqueous solution at 18 °C, of between -1 and 4.
Patent CA-2265810-A1 (CA)
Inventor: RALPH LOREN E
IPC: H03D7/14
Filed: 1997-09-17
Abstract: A thick film construct and quadrature coupler for use in fabricating devices such as IQ modulators, IQ demodulators, vector modulators, image reject mixers, and multi-channel mixers. The thick film construct includes a dielectric substrate base with a metallized backside, a first metal trace deposited on the non-metallized side of the substrate base, a dielectric layer deposited over and around the first metal trace, and a second metal trace deposited on the dielectric layer. The first and second metal traces are aligned over their widths and lengths so to form a balanced transmission line structure where the first and second metal traces represent top and bottom lines in the balanced structure. This thick film structure serves as the foundation for microwave capacitors, mixers, and other transmission line based structures, including a quadrature coupler. The quadrature coupler which, in turn forms the basis for more complex devices, includes an input port, an isolated port, in-phase output port (I-port), and quadrature phase output port (Q-port).
Patent CA-2268862-A1 (CA)
Title: Melting apparatus and method for melting metal
Inventor: WIGCHERT ALBERTUS JOHANNES MAR
IPC: F27D3/00
Filed: 1997-10-09
Abstract: Melting apparatus for melting a metal, such as aluminium, compris-ing a melting chamber, a burner chamber and a passage which extends between the melting chamber and the burner chamber and which has an inlet opening on the melting-chamber side and an outlet opening on the burner-chamber side for allowing molten metal to pass from the melt-ing chamber to the burner chamber, circulation means being suitable for transferring molten metal from a first or suction connection to the burner chamber to a second or pressure connection to the melting chamber. Ac-cording to the invention, the residual bath when changing the metal com-position is minimised and productivity maximised.
Patent CA-2268875-A1 (CA)
Inventor: KYDONIEUS AGIS
IPC: A61K31/23
Filed: 1997-10-17
Abstract: The invention relates to compositions of skin-derived lipids that inhibit the ability of microorganisms to adhere to skin, inhibit the reproduction of microorganism and are toxic to microorganisms. The invention includes the two fatty acids shown below the derivatives or analogs thereof: derived as shown in the figure.
Patent CA-2275398-A1 (CA)
Inventor: CELNIKER GEORGE WILLIAM
IPC: G01V11/00
Filed: 1997-12-18
Abstract: A method, computer system, and computer program for analyzing geological data sampled from a subsurface region and an analysis of the geological data stored in a geoscience model on a magnetic media, including building a simulation input model from the geoscience model. A method, computer system, and computer program for analyzing geological data sampled from a subsurface region, the geological data and an analysis of the geological data being stored in a geoscience model on a magnetic media, including constructing a boundary for dividing the region into a first sub-region and a second sub-region; storing on the magnetic media the shape of the boundary as a parametric function whose parameter density can vary. A method, computer system, and computer program for analyzing geological data sampled from a subsurface region, the geological data and an analysis of the geological data being stored in a geoscience model on a magnetic media, including dividing the region into sub-regions, in each of which a material property varies without discontinuities.
Patent CA-2276755-A1 (CA)
Title: Branched structures for supporting multiple electrode elements
Inventor: WHAYNE JAMES G
IPC: A61F2/958
Filed: 1997-12-11
Abstract: A catheter assembly comprises a first branch (44) having a first axis, a second branch (32) extending in a non-parallel relationship with respect to the first axis and at least one electrode (28) carried by the second branch body (32). In use, the first branch body (44) can be located within a pulmonary vein within the left atrium, while the electrode (28) carried by the second branch body (32) is located in contact with endocardial tissue outside the pulmonary vein. Ablation energy can be transmitted from the electrode (28) to contacted endocardial tissue while the first branch (44) body is located within the pulmonary vein.
Patent CA-2277716-A1 (CA)
Inventor: CHANG CHIH-CHEN
IPC: B60N3/04
Filed: 1999-07-12
Abstract: The present invention relates to a chain shape lamp, comprising of several chain rings stringing together. Wherein the chain ring is a detachable hollow tube, thereby locate bulbs and wire the cord at inside. The chain shape lamp provided by the present invention has a simple structure, easy assembling, and convenience for locating the bulbs and wiring the cord features, and meeting the necessary of large-scale production.
Patent CA-2278023-A1 (CA)
Title: Modulateurs de l'activite du recepteur d'insuline
Inventor: VILLAR HUGO O
IPC: A61K31/655
Filed: 1998-01-15
Abstract: L'invention concerne des procédés servant à identifier les composés qui possèdent au moins une caractéristique sélectionnée dans le groupe constitué d'une composition qui (a) module l'activité de la kinase du récepteur d'insuline; et/ou (b) potentialise l'activation insulinique du récepteur d'insuline; et/ou (c) potentialise la stimulation par l'insuline de l'absorption du glucose dans les cellules; et/ou (d) stimule l'absorption du glucose dans les cellules possédant le récepteur d'insuline; et/ou (e) baisse la glycémie chez les sujets diabétiques; et/ou (f) stimule la phosphorylation de IRS-1; et/ou (g) stimule l'activité de la kinase PI¿3?; et/ou (h) stimule la translocation de GLUT-4. Les compositions efficaces possédant ces caractéristiques modifient la conformation du domaine à deux lobes de la kinase cytoplasmique ou, de préférence, se lient à des sites ayant été identifiés comme site de liaison des modulateurs dans la chaîne .beta. du récepteur d'insuline. L'invention permet également de moduler l'activité du récepteur d'insuline, d'activer l'absorption du glucose par les cellules, et de produire d'autres effets importants en rapport avec le traitement et la surveillance du diabète grâce à l'utilisation de composants répondant à la formule (1) dans laquelle chaque Ar est indépendamment un fragment aromatique; chaque A est indépendamment un substituant accepteur de protons; chaque R est indépendamment un substituant non interférant; m est 0, 1 ou 2; n est 1-6; et chaque élément de liaison est indépendamment -CH¿2?-, -N=N-, -CH=CH-, -NHCO- ou -NHCONH- ou leur isostère, n étant égal à 1 et au moins un Ar devant comprendre au moins deux cycles aromatiques condensés. On peut aussi utiliser les composés du type de la formule (1) pour étudier l'activité structurelle afin d'identifier les caractéristiques responsables des activités correspondantes.
Patent CA-2281785-A1 (CA)
Title: Transparent liquid detergent containing alkylbenzenesulfonate anionic surfactant and sodium silicate
Inventor: UNO MINORU
IPC: C11D1/52
Filed: 1998-12-17
Abstract: A water-base transparent liquid detergent which contains an alkylbenzenesulfonate anionic surfactant, liquid sodium silicate, a polyoxyethylene alkyl or aryl ether nonionic surfactant, and an alkyl ether sulfate salt anionic surfactant.
Patent CA-2282901-A1 (CA)
Title: Furnace for producing dental prostheses
Inventor: ROHNER GOTTFRIED
IPC: A61C13/20
Filed: 1999-09-17
Abstract: A muffle furnace for producing dental prostheses has a muffle into which dental material is placed and a drive to which a piston is connected. The piston is moveable by the drive into the muffle to apply pressure onto the dental material. A pressure sensing device for measuring pressure applied to the dental material is provided. The pressure sensing device has a pressure sensor and a deformation member having a first side and a second side. The first side of the deformation member is subjected to a counter force of the piston and the second side of the deformation member is fixedly attached to the muffle furnace.
Patent CA-2282931-A1 (CA)
Title: A contact center system capable of handling multiple media types of contacts and method for using the same
Inventor: KORZENIOWSKI GARY E
IPC: H04Q3/64
Filed: 1999-09-21
Abstract: A contact center system and method employing a plurality of agent workstations, and which includes a queuing component, capable of receiving contacts of different media-types, such as telephone calls, e-mails, facsimiles, web chat, voice over internet protocol, and so on, and maintaining the different media types contacts in a common queue while awaiting routing to the agent workstations. The system further comprises a routing component which routes the queued contacts to the agents based on criteria of the contacts, criteria of the agents, or both. A media changing component of the system is capable of changing a media-type of any of the media-type contacts to generate a changed media-type contact, while the queuing component is capable of entering the changed media-type contact in the common queue, and the routing component is capable of routing the queued changed media-type contact to at least one of the workstations. A contact handling component initiates an event at any of the workstations in response to the contact being routed to the workstation, so that an agent at the workstation can handle the contact as appropriate.
Patent CA-2284107-A1 (CA)
Title: Activation of peptides
Inventor: CLARKE DAVID JOHN
IPC: A61K47/48
Filed: 1998-03-18
Abstract: A method of producing a peptide, the function of which may be altered in a reversible and/or competitive manner, optionally confined to an active site thereof, is described. The peptide produced according to the method is usable in assays, purification methods and in medicine.
Patent CA-2286033-A1 (CA)
Title: Butterfly valve
Inventor: TUBARO BRUNO
IPC: F16K31/53
Filed: 1998-04-06
Abstract: A throttle valve comprising a throttle plug (3), which cooperates with a valve seat (2, 5, 6), having a substantially annular gasket (5) which, when the throttle plug (3) is in the closing position, adheres with a certain compressive force, transverse to the flow direction, against the peripheral end edge of the plug (3). According to the invention, at least a part of the compressive force acting between the gasket (5) and the end edge of the plug (3) is exerted by the hydrostatic pressure of the fluid intercepted when the valve is in the closing condition. The gasket (5) has compression surfaces (605), in a radially outer position with respect to the surface contacting the peripheral end edge of the plug (3), turned opposite the contact surface between the gasket (5) and the plug (3), and being oriented in such a way that at least one of their directional components is parallel to the flow, in order to generate a compression perpendicular to the flow. Said surfaces (605) are accessible and exposed to the intercepted fluid.
Patent CA-2286118-A1 (CA)
Title: Aromatics alkylation
Inventor: MAZZONE DOMINICK NICHOLAS
IPC: C07C2/66
Filed: 1997-04-15
Abstract: Alkyl aromatic compounds are prepared by alkylating an alkylatable aromatic compound with a paraffin alkylating agent under alkylation reaction conditions in the presence of catalyst comprising synthetic porous crystalline material characterized by an X-ray diffraction pattern including interplanar d-spacings at 12.36 ~ 0.4, 11.03 ~ 0.2, 8.83 ~ 0.14, 6.18 ~ 0.12, 6.00 ~ 0.10, 4.06 ~  0.07, 3.91 ~ 0.07, and 3.42 ~ 0.06 Angstroms.
Patent CA-2286288-A1 (CA)
Title: Monoclonal antibody recognizing the n-glycolylated-galacotose-glucose sialic acid oligosaccharide in malignant tumors and composition that contains it
Inventor: VAZQUEZ LOPEZ ANA MARIA
IPC: C12P21/08
Filed: 1999-02-05
Abstract: The present invention relates to the branch of immunology and human medicine, in particular to the generation and selection of a monoclonal antibody which recognizes the oligosaccharide N-glycolylated-galactose-glucose sialic acid (NGcNeu-Gal-Glu) present in malignant tumors. One of the objects of this invention is to provide a monoclonal antibody of the IgG1 type which has the characteristic of recognizing with a high specificity the oligosaccharide sequence N-glycolylated-galactose-glucose sialic acid present in malignant mammary tissues as well as in melanomas and tumors of the liver, stomach, colon, rectum and kidney. It also has the capacity of causing direct cytolysis in tumoral cells which carry said oligosaccharide sequences and, as a consequence, can be used for the diagnosis and treatment of certain neoplasic diseases. Another object of the present invention is to provide the hybridome producing said monoclonal antibody, as well as the pharmaceutical composition containing it, for the treatment of neoplasic diseases.
Patent CA-2286888-A1 (CA)
Title: Settler plate supports with integral outlets for individual flow channels and methods of collecting liquid from each flow channel
Inventor: MEURER CHARLES LONNIE
IPC: B01D21/08
Filed: 1999-10-15
Abstract: Improved settlement of solids is provided, while minimizing problems in collecting clarified liquid from a clarifier, by controlling the flow of clarified liquid from a given one of many flow channels of a clarifier. Such control is by causing a substantial amount of that flow of clarified liquid to be collected immediately as that flow exits the given flow channel. Such collection of the substantial amount, if not all of that flow of the clarified liquid from the given flow channel, minimizes if not eliminates, the mixing of the flow from all of the flow channels of a clairfier. As a result, during normal settling operations the flow of the clarified liquid from the given flow charmel is substantially isolated. During such normal operations, the isolated flow may be separately sampled for examination of the performance of the separate flow channel. If too many solids are present in the clarified liquid from that separate flow channel then one or both of the plates that define that separate flow channel may be removed and replaced. Servicing operations of removal and replacement of the one or both plates are performed without interrupting the normal settling operations of the other flow channels.
Patent CA-2287342-A1 (CA)
Title: Monofilaments with split ends
Inventor: RACKLEY ROBERT L
IPC: D01F6/60
Filed: 1997-04-24
Abstract: Monofilaments with split ends. The monofilaments can be used to form toothbrush bristles having flagged or feathered tips. Each of the monofilaments has a plurality of internal fusion lines and at least four voids, wherein the voids comprise between 5 and 20 % of the cross-sectional area of the monofilaments. Preferably, the monofilaments each have a diameter in a range of 0.0025 to 0.012 inches, and have a hexalocular or an octalocular configuration.      The monofilaments are manufactured by extruding a plurality of thermoplastic polymeric streams, rotating a plurality of cutting blades above 1000 rpm, and placing a plurality of cutting blades in contact with end portions of the plurality of thermoplastic polymeric streams to form split ends.
Patent CA-2290589-A1 (CA)
Title: Dual trailing arm vehicle suspension
Inventor: PIERCE WILLIAM C
IPC: B60G11/26
Filed: 1998-05-19
Abstract: A suspension system for a vehicle includes a longitudinally extending frame, an axle (44) connected to the frame for relative movement with respect thereto, an air spring (38) mounted between the frame and the axle to yieldably support the axle with respect to the frame, and upper (22) and lower (24) trailing arms attached to each side of the frame. A first torsion bar (58) extends between and is rigidly attached to the upper trailing arms and a second torsion bar (60) extends between and is rigidly attached to the lower trailing arms. The torsion bar cooperates with the springs during deflection of the suspension system with respect to the frame to thereby yieldably resist relative movement between the trailing arms and the frame. In one embodiment, the upper and lower trailing arms are parallel to each other. This arrangement results in load equalization between the suspension assemblies. Any relative torque caused by deflection of the trailing arms is equally distributed between both torque bars. In another embodiment, the upper (63) and lower (64) trailing arms are non-parallel, and arranged such that when the trailing arms pivot due to road conditions or vehicle loading, fore and aft movement of the air spring and axle due to arcuate swing of the trailing arms is minimized.
Patent CA-2290763-A1 (CA)
Inventor: NOTARGIACOMO MASSIMO
IPC: G02B6/42
Filed: 1999-11-25
Abstract: An external analog modulation system is described, comprising an electro-optical modulator with a double output and a driving circuit.      In particular, it comprises an optical source, an electro-optical modulator, an electrical modulating signal and a driving circuit for said electro-optical modulator, said electro-optical modulator having two optical outputs, supplying a first and a second modulated optical signal, which are complementary to each other, each of said two optical outputs of said modulator being connected to an optical coupler having a branch supplying a portion of modulated optical signal and connected to an optical receiver, capable of generating a first and a second electrical control signal correspondingly in response to a first frequency of said first and second analog modulated optical signals, in which said driving circuit comprises a circuit generating an electrical pilot signal at a second frequency, equal to half of said first frequency, added to said electrical modulating signal; a conversion circuit capable of producing a continuously converted signal proportional to the difference in amplitude between said first and said second electrical control signal; and a bias circuit capable of generating a bias signal in response to said control signal.
Patent CA-2292212-A1 (CA)
Title: Panel attachment system
Inventor: KRIEGER KEVIN
IPC: E04F13/08
Filed: 1999-12-15
Abstract: A wall system comprising a plurality of rectangular rigid prefinished panels mounted on a wall support structure with main, runners and cross runners. The main runners serve to lock the panels onto the support structure and with the cross runners serve to prevent the panels from warping due to adverse moisture conditions. The main runners are configured to space the panels from the wall support structure to encourage uniform humidity conditions at the front and rear of the panels. Clips that secure the panels to the main runners are fixed adjacent the top and bottom panel edges at different set-offs to obtain an advantageous nesting of panels for reduced packaging volume.
Patent CA-2295693-A1 (CA)
Title: Mutant .alpha.-amylase having introduced therein a disulfide bond
Inventor: DAY ANTHONY G
IPC: C11D3/386
Filed: 1998-06-29
Abstract: Novel .alpha.-amylase enzymes are disclosed in which one or more disulfide bonds are introduced into the enzyme via addition or substitution of a residue with a cysteine. The disclosed .alpha.-amylase enzymes show altered or improved stability and/or activity profiles.
Patent CA-2296177-A1 (CA)
Title: Side wall for an ink fountain of a printing machine
Inventor: FINA RAFFAELE
IPC: B41F31/18
Filed: 2000-01-17
Abstract: The side wall (5) for an ink fountain of a printing machine, comprises at least two plates (11, 14) fixed some distance apart and an intermediate plate (13) having a front edge (13a) in the shape of an arc of a circle mounted between said plates in such a way that it can be shifted and tilted, said front edge being intended to come into contact with the circumference of an ink fountain roller (6) via press means (18, 19) acting on said intermediate plate. The wall comprises a slideway (10) in which the plates (11, 14, 13) are mounted, the slideway having a reinforced region (12) on one of its sides which is intended to be close to said ink fountain roller (6).
Patent CA-2297183-A1 (CA)
Inventor: FOLAN MICHAEL ANTHONY
IPC: A61K35/54
Filed: 1998-07-23
Abstract: Medicaments formed from maternal immune secretion having biological activity characteristic of human saliva and other mucosal secretion and which is tolerated by humans can be used for the treatment and/or prophylaxis of conditions of the human body such as the buccal cavity characterised by a loss of normal mucosal or the normal biological properties thereof. The secretions are suitably egg fluid or milk from a domestic animal or replicas thereof.  These secretions can be enriched with the native immunoglobulin found therein so that they have a potency which approximates that of hyperimmunised immunoglobulin. The medicaments have particular application in the treatment and/or prophylaxis of oral infection, dental caries, conditions of the buccal cavity characterised by inflammation, xerostomia and halitosis.