baber/WOPTO huggingface dataset:
Patent EA-201992226-A1 (EA)
Title: Агонисты npra, композиции и их использование
IPC: C07K1/107
Filed: 2018-03-21
Abstract: Настоящее изобретение раскрывает производное натрийуретического пептида формулы (I) и композиции, содержащие производное натрийуретического пептида формулы (I),где z представляет собой 1, x представляет собой целое от 2 до 4 и y представляет собой 3; или z представляет собой 0, x представляет собой целое от 0 до 4 и y представляет собой целое от 1 до 3; жирный ацил содержит от 12 до 24 (например, от 12 до 18) атомов углерода; В представляет собой лизин или аргинин; G представляет собой глицин; NP представляет собой натрийуретический пептид; если присутствует (жирный ацил)- ковалентно связывают с N-концом в (B); (жирный ацил)-(B)- ковалентно связывают с N-концом в (G); и (жирный ацил)-(B)-(G)- ковалентно связывают с N-концом в NP. Производное натрийуретического пептида в соответствии с раскрытием и его композиции можно использовать при лечении заболеваний, таких как гипертензия, сосудистый застой и заболевание сердца.
Patent EA-201992292-A1 (EA)
Title: Контейнер для долгоживущих радиоактивных отходов от низкого до высокого уровня активности
IPC: G21F5/005
Filed: 2018-04-05
Abstract: Изобретение относится к контейнеру для радиоактивных отходов, содержащему стальную внешнюю стенку, стальную внутреннюю стенку, расположенный между двумя стальными стенками слой свинца, стальное дно, стальную крышку, объем расположенного внутри контейнера кварцевого песка, по меньшей мере один внутренний сосуд/кассету/внутреннюю камеру, по меньшей мере, частично закрытый по окружности объёмом кварцевого песка, и расположенные внутри контейнера радиоактивные отходы. Внутренний сосуд может быть изготовлен из нержавеющей стали и может содержать низкоуровневые радиоактивные отходы. Альтернативно сосуд(ы) может быть изготовлен из керамики и может содержать высокоуровневые радиоактивные отходы. В одном предпочтительном варианте осуществления контейнер может содержать внутренний стеллаж, на котором расположены внутренние сосуды.
Patent EA-201992684-A1 (EA)
Title: Материалы и способы конструирования клеток и пути их применения в иммуноонкологии
IPC: C12N15/60
Filed: 2018-05-11
Abstract: Материалы и способы получения клеток с отредактированным геномом, сконструированных для экспрессии конструкции химерного антигенного рецептора (CAR) на поверхности клетки, и материалы и способы редактирования генома для модулирования экспрессии, функции или активности одного или нескольких генов клетки, связанных с иммуноонкологией, а также материалы и способы лечения пациента с применением сконструированных клеток с отредактированным геномом.
Patent EA-202190358-A1 (EA)
Title: Способы генной терапии для контроля функции органов
IPC: C12N15/86
Filed: 2019-07-31
Abstract: Предложены способы и композиции для контроля функции висцерального органа. Например, указанные способы и композиции применимы для предотвращения, ингибирования или лечения заболевания в результате контроля, например регулирования функции органа. В одном варианте осуществления в орган доставляют вирусные векторы, и вирус инфицирует нерв, который регулирует функцию органа. В одном варианте осуществления вирусный вектор представляет собой ретроградный вектор. В одном варианте осуществления вирусный вектор кодирует генный продукт, активность которого контролируют экзогенно доставляемыми агентом или энергией. Таким образом, доставка агента или энергии контролирует функцию органа.
Patent EA-202192601-A1 (EA)
Title: Иммунотерапевтические композиции и их применение
Filed: 2020-03-30
Abstract: Описаны комбинированные виды терапии для лечения рака, включающие иммуностимулирующие слитые молекулы, которые включают фрагмент для нацеливания на иммунную клетку и цитокиновую молекулу; а также иммунная клетка, нагруженная белковыми наногелями, которые включают обратимо поперечно связанную цитокиновую молекулу и полимер, а также лекарство и составы на их основе, и способы их применения и получения.
Patent ES-2187230-A1 (ES)
Title: Improvements to hydroponic or conventional irrigation and fertilisation installations
Inventor: SOLSONA ESTRADE JAUME
IPC: A01G25/16
Filed: 2000-03-06
Abstract: Improvements to hydroponic or conventional irrigation and fertilisation installations.The improvements are based on a controller and peripherals for conventional or hydroponic irrigation and fertilisation according to parameters of conductivity, acidity, solar radiation, temperature, rain, relative humidity, soil humidity, evaporation, trunk or fruit swelling, etc. Models with up to 200 irrigation valves, 6 engines, 8 fertilisers, 2 acids or bases, shakers, filters, alarms, etc., with configurable digital and analogue inputs. It can include CE and pH injection and drainage probes, bioclimatic probes, level probes, etc. It is equipped with 24 irrigation and fertilization programmes with probe conditions, automatic development curves, drainage, etc., and multiple error, event, etc. history logs. It links to a personal computer, acts on valves via radio, regulates the irrigation pressure, mixes two different quality waters, and provides information and control via short GSM telephone messages.
Patent ES-2186487-A1 (ES)
Title: Microporous crystalline material (itq-15), method for the preparation thereof and its use in processes for separating and transforming organic compounds
Inventor: CORMA CANOS AVELINO
IPC: C01B39/48
Filed: 2000-10-11
Abstract: A microporous crystalline material of a zeolitic nature that, in a calcinated and anhydrous state, has a chemical composition represented by the formula: X (M1/nXO2) : y YO2 : z GeO2 : (1-z) TO2 wherein x has a value below 0.2, y has a value below 0.1, z has a value below 1, with at least one of x, z and y being above zero M is H+ or at least an inorganic cation with a +n charge X is at least one chemical element with a +3 oxidation status Y is at least one chemical element with a + oxidation status and T is at least one chemical element with a +4 oxidation status (Si, Ti, Sn, V), this material having a specific X-ray diffraction pattern. A method for preparation of the material and its use as a catalyst in organic compound separation and transformation processes is also described.
Patent ES-2189618-A1 (ES)
Title: Set of boron-based solid propellants comprises amorphous products with aluminum, magnesium and coke as reduction agent decreasing boron oxide formation
Inventor: MOTA JOSE MANUEL
IPC: C10L5/40
Filed: 2001-01-26
Abstract: Boron-based fuels obtained using powder technology, for civilian and military rocket reactors and engines, with an amorphous structure, to which is added a reducer such as aluminium, magnesium, coke, etc. The fuel can have a boron content of up to 99% weight.Boron generates a large amount of combustion heat per unit of volume, hence its great usefulness for use in solid propellants. The problem lies in the formation of superficial boron oxide during heating, delaying ignition and decreasing combustion yield, since part of this occurs outside the engine.The solution provided is the inclusion of a chemical reducer to the boron structure. Thus, the oxides will continue to decrease even as they are produced during the ignition process.
Patent ES-2178594-A1 (ES)
Title: Procedure for controlling the enumeration of the absolute count of cells or other particles present in a sample
Inventor: ORFAO DE MATOS CORREIA E VALE
IPC: G01N15/10
Filed: 2001-02-20
Abstract: Procedure for controlling the enumeration of the absolute count of cells (or other particles) present in a sample. The procedure consists of the following: to prepare, in known quantities and proportions, a mixture or stock solution of two or more populations of reference particles of differing characteristics to add a known quantity of this mixture of reference particles to a known volume of the sample which contains the cells (or other particles) to be counted to measure, in a flow cytometer, the sample containing both the cells (or other particles), the events of which are to be counted, and the mixture of different populations of reference particles to calculate the absolute number of cells (or other particles) present in the sample to be counted and to check that the proportion between the different reference particles present in the sample measured concurs with the proportion that exists between them in the initial mixture or stock solution which contained the different populations of reference particles prior to adding it to the sample.
Patent ES-2190331-A1 (ES)
Title: Inlet and exhaust valve system for engines.
Inventor: RODIL MENDEZ JOSE LUIS
IPC: F01L13/00
Filed: 2001-03-29
Abstract: Inlet and exhaust valve system for engines.Applicable both to explosion and internal combustion engines in which each cylinder (3) has a mechanical inlet valve (8) and another for exhaust, driven by the camshaft (9). Each chamber (3) also includes at least one inlet valve (12) and another for exhaust of the electromechanical type, each fitted with electromagnetic coils (14) and (15), one for opening and one for closing, controlled by an electronic control unit (17) which controls the timing of the opening and closing of the said valves (12) as well as the time they remain open or closed, in order to obtain the maximum efficiency of the engine and minimum fuel consumption, the said electronic unit (17) generating a train of valve (12) control pulses based on information received from a series of sensors, namely a rotation sensor (18) and an angular rotation sensor (23), which work with a toothed wheel (22), a pressure sensor (25), fitted with a membrane (26) connected to the inlet manifold (9) and optionally sensors that detect the temperature of the engine, the inlet air, or any other parameter that influences the conditions of explosion or combustion of the mixture in the chamber (3).
Patent ES-2204298-A1 (ES)
Title: Flushing device for toilet cisterns
Inventor: BLANCO GUTIERREZ JOSE
IPC: E03D1/14
Filed: 2002-07-16
Abstract: The invention relates to a quantified water-saving device which performs a controlled dual flush by means of a single button. The inventive device is adapted to a cistern using an impervious element (2) and the cover is fixed using an adjustable anchoring bridge (7). Said device comprises a float assembly consisting of two floats, namely an upper float with greater floating power (11) and a lower float with less floating power (12), and a rocker-type connecting part (13) which ensures that the aforementioned floats act in a co-ordinated, alternating manner. In this way, when the button (10) is pressed, the toilet is flushed in the following manner: 1) when the button is pressed once, without having to be held down, a pre-fixed volume of liquid is partially emptied in a controlled manner under the main action of the upper float (11) and 2) when the button is pressed a second time, without having to be held down, during the refilling operation following the aforementioned partial flush, the tank is fully emptied under the main action of the lower float (12).
Patent ES-2234408-A1 (ES)
Title: Water saving device for use in water tank of closet, has outlets provided on main water tank, where water tank is directly connected to secondary reservoir, and water washing unit and dishwasher provided on water tank
Inventor: AHMED GUMAA BUSHARA
IPC: E03D5/00
Filed: 2003-07-11
Abstract: The device has a water washing unit (2) and a dishwasher (3) provided on a main water tank (6). A washing machine and the water tank are located in a closet (1). A secondary reservoir receives water through connection units (4, 5). The water tank is directly connected to the secondary reservoir. Outlets (7, 10) are provided on the water tank.
Patent ES-2292273-A1 (ES)
Title: Use of luminescent ruthenium (II)-type pigments in security documents, the process and device to detect them
Inventor: ORELLANA MORALEDA GUILLERMO
IPC: C07F15/00
Filed: 2004-07-13
Abstract: Luminescent pigments (1) of the type used in security documents or goods (2), or the combination of several luminescent pigments (1), which have specific luminescent characteristics such that the illumination response of each luminescent pigment (1) is different, enabling these security documents to be coded (2), and the method and device used to detect these luminescent pigments.
Patent ES-2259878-A1 (ES)
Title: Set of concrete and mortar mixed reinforcing fibers consists of twisted, heated, molded and shaped products
Inventor: PALACIOS GAZULES SERGIO
IPC: D01F8/06
Filed: 2004-08-03
Abstract: The set of concrete and mortar mixed reinforcing fibers comprises products of variable size, length and shape. Also claimed is a process making the fibers. CLAIMED PROCESS - The process twists, heats, molds and cuts the fiber materials.
Patent ES-2250004-A1 (ES)
Title: Controller for activation of space devices or electronic components, includes emitter module with signal emitter for irradiating visible light, coded by pulses or in frequency, towards optical sensor of receiver module
Inventor: ROCASALBAS ARGEMI JORDI
IPC: H05B37/02
Filed: 2004-09-30
Abstract: The controller includes an emitter module and a receiver module. The emitter module has a signal emitter for irradiating visible light in sensible parallel rays that can be oriented by a user for direct incidence to the optical sensor of the receiver module. The visible light is coded by pulses or in frequency.
Patent ES-2301361-A1 (ES)
Title: Material with fullerene-type structure, production method and applications thereof
Inventor: CAMERO HERNANZ MANUEL
IPC: C23C16/34
Filed: 2006-05-12
Abstract: The invention describes a carbon-based material with fullerene-type structure and more specifically consists of sp2 hybridization carbon partially hydrogenated up to an atomic content of 35%, preferably between 5 and 35%. The method for producing it is performed on a substrate at low temperature - between 25 and 300 DEG C - using the plasma-assisted chemical vapour deposition (PACVD) technique, containing, within it, highly energized ions and applicable to non-heat-resistant materials covering a wide range of applications. These materials are useful for the production of, for example, mechanical or optical devices, magnetic means, aircraft wings, glasses and plastics or photodetectors.
Patent ES-2320074-A1 (ES)
Title: Storage box
Inventor: LOPEZ MASAGUE MANUEL
IPC: B65D5/10
Filed: 2007-05-14
Abstract: The storage box is formed from a sheet provided with a plurality of folding lines defining a parallelepiped provided with six faces, one of said face being a hinged lid (2), and it is characterised in that the opposed face to said hinged lid comprises a first sector (1a) provided with an oblique folding line (7a) that defines a first joining zone (8a) a second sector (1b) also provided with an oblique folding line (7b) that is joined to said first sector (1a) in said first joining zone (8a) a third sector (1c) provided with an oblique folding line (7c) that defines a second joining zone (8c) and a fourth sector (1d) that is joined to said third sector (1c) in said second joining zone (8c). It permits to obtain a box that can be mounted by itself.
Patent ES-2356975-A1 (ES)
Title: Door for accesses of elevator apparatuses, elevator apparatus and method for operating said door
Inventor: MURUA XABIER
IPC: B66B13/08
Filed: 2008-12-19
Abstract: The invention relates to a door for accesses of elevator apparatuses, elevator apparatus and method for operating said door, which allows improving the efficiency of the space occupied by the elevator apparatus, improving its ergonomics and safety, comprising at least two leaves (1, 1') configured to move between a closed position, in which said leaves (1, 1') close an access (2, 3) of the elevator apparatus, said leaves (1, 1') being opposed at their side edges (4) and said side edges (4) being flush with one another, and an open position, in which said access (2, 3) is open, said leaves (1, 1') being opposed at their faces (5). The method for operating said door between the closed position and the open position comprises a first phase in which the leaves (1, 1') move without relative movement and being laterally connected to one another and a second phase in which the leaves (1, 1') move with relative movement and being laterally disconnected from one another.
Patent ES-2347121-A1 (ES)
Title: Multipotent stem cells obtained from an adult thymus
Inventor: TINAHONES MADUENO FRANCISCO JOSE
IPC: C12N5/0775
Filed: 2009-04-24
Abstract: The present invention relates to multipotent stem cells derived from the thymus and, preferably, from the fatty tissue, capable of differentiating and producing cells with the characteristics of specialised cells, and to the methods for obtaining such cells. Said cells can be used for preparing drugs and pharmaceutical compositions for the prevention or treatment of lesions and degenerative or genetic diseases, as well as for assessing the cellular response to biological or pharmacological agents. Furthermore, the present invention relates to the use of fatty cells from the thymus of mammals for inducing angiogenesis in at least one isolated endothelial cell as well as to a method for achieving said induction.
Patent ES-2469265-A1 (ES)
Title: Methods for selecting therapy for cutaneous t-cell lymphoma
Inventor: PIRIS PINILLA MIGUEL ANGEL
IPC: C12Q1/68
Filed: 2012-11-14
Abstract: The invention relates to a method for selecting a therapy for the treatment of a patient with cutaneous T-cell lymphoma (LCCT), said method comprising determining the presence of a mutation in the PLCG1 gene in a sample from said patient, and selecting the therapy according to the mutational profile of the patient.
Patent ES-2530214-A1 (ES)
Title: Analytical immunosensor device and method for constructing same
Inventor: DOMINGUEZ CANAS ELENA
IPC: G01N33/53
Filed: 2013-02-19
Abstract: The invention relates to an analytical immunosensor device and to a method for the constructing same, based on the sequential deposition of self-assembled monolayers of polymers and affinity elements, applicable for the detection and quantification of any target antigen or analyte in a liquid sample, and allowing the implementation of the "quasi-reagentless" or "reagentless" displacement assay, the minimisation of the non-specific adsorption and, as a result, the reduction of the detection limit. Said device is designed on the basis of a sensor surface covered with polymer monolayers (redox or non-redox) on which are deposited sub-monolayers of affinity elements, in order to subsequently carry out the affinity reaction with an antigen, pseudo-antigen or a hapten marked with a protein, preferably an enzyme (redox or non-redox) or a nanoparticle, allowing said method for constructing the device to develop "a la carte" immunosensors, with an electrochemical, optical and/or piezoelectric transduction of the signal.
Patent JO-P20180034-A1 (JO)
Title: The Combinatorial Methods of High Pressure and Temperature Process ‎ ‎ (HPTP) for Producing Texturized Meat Products and the Improved Meat ‎ Products Obtained from The Methods Thereof
Inventor: KUMKANOKRAT WARAPORN
Filed: 2018-04-11
Abstract: A method of preparing a meat product is disclosed. The method can comprise providing meat having a first texture, the first texture comprising a plurality of loosely-bound or unbound pieces of the meat. The meat with the first texture can be placed in a chamber. The temperature and the pressure in the chamber can be simultaneously increased to change the first texture to a second texture comprising a single unified body of meat, the second texture of the meat being sliceable.
Patent JO-P20190303-A1 (JO)
Title: Wear assembly
Inventor: CHRISTOPHER M CARPENTER
Filed: 2006-02-17
Abstract: A wear assembly for securing a wear member to excavating equipment that includes a base having a nose and a wear member having a socket. The nose and socket are each provided with one or more complementary stabilizing surfaces in central portions thereof.
Patent JO-P20200276-A1 (JO)
Title: Magl inhibitors
Inventor: BUZARD DANIEL J
Filed: 2019-05-14
Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
Patent RS-20120536-A1 (RS)
Title: Method for automatic selection of the test sequences of commands
Inventor: PEKOVIĆ VUKOTA
IPC: H04B17/00
Filed: 2012-12-04
Abstract: The invention covers a method for intelligent selection of the test sequences of commands (combination of commands) to be used in automated functional testing of multimedia devices. The combination of commands that the user is selecting represents one test sequence of commands. Each test sequence of commands is modeled by a diagram of the transition probabilities. Each command characterizes one state in a state diagram. The method involves the analysis of all test sequences of commands in order to select the optimal test sequences of commands and defining the number of their repetitions in order to achieve a given accuracy testing. Besides the transition probabilities the selecting of optimal test sequence of commands is based on the belonging of the current test sequence to a particular group of commands with the aim to optimize the testing process.
Patent RS-20191679-A1 (RS)
Title: The movable curtain for protection, above all, from the sun
Inventor: PETRIĆ ĐORĐE
IPC: E04H15/00
Filed: 2019-12-26
Abstract: The movable curtain for protection, above all, from the sun, belongs to the field of construction, and in general, it can belong to the field of current life needs, that is, the design of sports fields. The invention consists of two curtains (1, 2) which are in the form of a right triangle whose one cathetus is longer than the other cathetus and four hollow poles (5, 6, 7, 8) whose one end is firmly connected to the ground in the corners of the space which needs to be protected from the sun. The other ends of the pole (5, 6) and the pole (7, 8) are tightly and pivotally interconnected to a spool (3, 4) made of aluminum alloy. The other ends of the pole (5, 8) and the pole (6, 7) are interconnected with the cable (9, 10). Inside the pole (5, 7) sprocket (18) is inserted and firmly connected, driven by a synchronous motor (37) which is supplied with a brake. Inside the pole (6, 8) is a tightly coupled pulley (23) which is driven by a synchronous motor (38) which is supplied with a brake. Along the hypotenuse of the curtain (1, 2), a rope (33) is firmly connected, and along the median straight line of the triangle shaped curtain, above the shorter cathetus, a rope (34) is firmly connected. The curtain (1, 2) is tightly connected to the spool (3, 4) by a shorter cathetus, and one end of the ropes (33, 34) is also tightly connected to the spool (3, 4). When unwinding the curtain (1, 2), the motor (38) winds the rope (33) onto the reel (29) by pulling the curtain (1, 2), and the motor (37) holds the curtain (1, 2) wound on the spool (3, 4) ). In the winding process, the process is reversed to keep the curtain (1, 2) flat in the winding process on the spool (3, 4).
Patent TR-201107481-A1 (TR)
Title: Vildagliptinin efervesan formülasyonları.
Inventor: CIFTER UEMIT
IPC: A61K9/46
Filed: 2011-07-29
Abstract: Buluş oral yolla ve suda disperse edilerek uygulanan efervesan kompozisyonu olup, vildagliptin veya vildagliptinin farmasötik olarak kabul edilebilir bir tuzunu, bir asit ve bir karbonat içeren partiküller ile bu partiküllerin içine yerleştirildiği hava ve nem bariyeri özellikli ambalaj içermesi ile karakterize edilmektedir.