baber/WOPTO huggingface dataset:
Patent CA-2218166-C (CA)
Inventor: NEVILLE DAVID M
IPC: A61K39/395
Filed: 1996-04-12
Granted: 2012-08-14
Abstract: Provided is a method of treating an immune system disorder not involving T-cell proliferation, comprising administering to the animal an immunotoxin comprising a mutant diphtheria toxin moiety linked to an antibody moiety which routes by the anti-CD3 pathway, or derivatives thereof under conditions such that the disorder is treated. Thus, the present method can treat graft-versus-host disease. Also provided is a method of inhibiting a rejection response by inducing immune tolerance in a recipient to a foreign mammalian donor tissue or cells, comprising the steps of: a) exposing the recipient to an immunotoxin so as to reduce the recipients' peripheral blood T-cell lymphocyte population by at least 80 %, wherein the immunotoxin is anti-CD3 antibody linked to a diphtheria protein toxin, wherein the protein has a binding site mutation; and b) transplanting the donor cells into the recipient, whereby a rejection response by the recipient to the donor organ cell is inhibited, and the host is tolerized to the donor cell.
Patent CA-2218189-C (CA)
Inventor: HECHT KURT
IPC: F21V29/505
Filed: 1996-11-27
Granted: 2001-02-06
Abstract: A high speed imaging apparatus for CCD based scanners comprises a housing having separate compartments which complement modular assemblies installed therein. A decoder compartment houses components as sociated with locating and decoding an image. An optics compartment houses the mirrors and associated optics for reflecting the s ubject image onto the CCD detector. A lighting compartment includes high intensity lamps and the associated components for illuminating an object to be imaged. The lighting compartment includes a heat management system which removes the heat from the high intensity lamps an d prevents heat from migrating to other compartments within the housing.
Patent CA-2229266-C (CA)
Title: Polyaluminum chlorides and polyaluminum chlorosulfates methods and compositions
Inventor: DULKO JAMES M
IPC: C01F7/786
Filed: 1996-08-29
Granted: 2001-10-16
Abstract: The present invention is directed to a process for the production of polyaluminum chlorides and polyaluminum chlorosulfates useful as coagulants in water treatment. In addition, the invention is directed to the products made by the disclosed processes.
Patent CA-2229850-C (CA)
Inventor: VANDERKLAAUW PETER M
IPC: B66F1/00
Filed: 1998-02-18
Granted: 2002-05-07
Abstract: The present invention provides a plurality of block-like building elements which may be bolted to each other to form a variety of support structures without the use of heavy hoisting equipment. Some of the building elements have a generally U-shaped appearance when viewed in plan, i.e., the building elements are open or slotted on one side so that a hydraulic cylinder or other lifting device may be inserted into the interior of the building element, or into a post formed from a stack of connected building elements. The lifting device may be used to preload the support structure. Advantageously, the lifting device may be used to progressively lift a load to a higher elevation by elevating the load a sufficient distance to enable the addition of an additional building element. The lifting device may then be repositioned within the structure for further elevating the load.
Patent CA-2230492-C (CA)
Title: Human growth hormone variants
Inventor: CLARK ROSS G
IPC: C12N15/63
Filed: 1996-09-20
Granted: 2009-05-26
Abstract: Human growth hormone variants are disclosed having enhanced affinity for the growth hormone receptor. Also disclosed are human growth hormone variants conjugated to one or more chemical groups, such as poly(ethylene glycol), which is believed to prolong the in vivo half-life of the variants.
Patent CA-2232194-C (CA)
Title: Figure location detecting system
Inventor: MONDEN AKIRA
IPC: F27D99/00
Filed: 1998-03-16
Granted: 2001-05-29
Abstract: A figure location detecting system is designed to detect a location of a first figure (e.g., search fingerprint) within a second figure (e.g., file fingerprint). Particularly, the system is designed to correctly match characteristic points of the first figure with characteristic points of the second figure even if the first figure contains a plenty of similar characteristic points whose characteristics are similar with each other and/or even if the first figure is (partially) distorted. Herein, the system creates matching characteristic point pair candidates each corresponding to a pair of a first characteristic point, corresponding to one of the characteristic points of the first figure, and a second characteristic point corresponding to one of the characteristic points of the second figure. The matching characteristic point pair candidates are created on the basis of relative characteristics which are calculated for proximity characteristic points which exist in proximity to the first and second characteristic points respectively. Then, the system narrows down the matching characteristic point pair candidates to matching characteristic point pairs by removing wrong  matching characteristic point pair candidates, each of which is detected as a wrong match in consideration of a matching situation of the proximity characteristic points. Coordinate matching parameters are produced with respect to each of the matching characteristic point pairs.          Thus, the system outputs most concentrated coordinate matching parameters which values of the coordinate matching parameters sequentially produced concentrate in most frequently.
Patent CA-2232359-C (CA)
Inventor: BAILEY BOBBY J
IPC: C08K5/3435
Filed: 1998-04-24
Granted: 2003-07-08
Abstract: Stabilized solution-dyed fiber is made by melting a polyamide which is amide monomers polymerized in the presence of at least one mono or dicarboxylic acid chain regulator and at least one hindered piperidine compound, coloring the melted polyamide, and spinning the colored polyamide into fibers that have about 40% or better retained tenacity after 2125 kJ exposure to xenon arc radiation as per AATCC Test Method 16-1993, "Colorfastness to Light," Option E. Copper stabilizers are unnecessary.
Patent CA-2235009-C (CA)
Title: Mecanisme de verrouillage a detente brusque pour cadre de levage de depanneuse
Inventor: YOUNG CHARLES E
IPC: B60D1/145
Filed: 1996-11-07
Granted: 2001-09-04
Abstract: Ensemble (25) support de roues et appareil de remorquage de véhicule. Ledit ensemble (25) support de roues comporte une rampe (26) et une paire de bras de levage (31A, 31B). Chaque bras de levage (31A, 31B) est constitué d'un segment (32) de bras d'extension fixé transversalement à la rampe (26), et d'un segment (33) de bras de contact doté d'un point de pivotement destiné au montage pivotant dudit bras à proximité de l'extrémité du segment (32) de bras d'extension, à distance de la rampe (26). Le segment (33) de bras de contact est constitué d'un segment (35) de bras d'actionnement et d'un segment (34) de bras de saisie qui s'étendent dans des directions différentes à partir du point de pivotement. Une paire d'actionneurs (41) linéaires sont fixés pivotants au mât (26), chacun possédant un segment (36) de bras fixe et un segment (37) de bras mobile. Le segment (36) de bras fixe de chaque actionneur linéaire est fixé transversalement au mât (26) et le segment (37) de bras mobile de chacun est fixé pivotant à un mécanisme (40) de verrouillage à détente brusque.
Patent CA-2238985-C (CA)
Title: Tapered bearing housing
Inventor: MAIER MARTIN D
IPC: F16C17/03
Filed: 1997-10-16
Granted: 2003-06-24
Abstract: A bearing structure having an annular cage (124) and an annular housing (114 ) that optionally mate at frustogeometrical surfaces (115a, 125) for supportin g and positioning a rotatable shaft (102) of a turbomachine and that optionall y provides a squeeze film damper between the frustogeometrical surfaces of the  annular cage and the annular housing. A bearing structure having an annular cage (124) and an annular housing (114) that optionally mate at frustogeometrical surfaces (115a, 124) for supporting and positioning rotatable shaft (102) of a turbomachine and that optionally provides an externally adjustable squeeze film damper between the frustogeometrical surfaces of the annular cage and the annular housing. The squeeze film dampe r is defined by two annular squeeze film seals (156a, 158a) positioned in respective annular squeeze film seal grooves (156, 158) formed in the frustogeometrical radially outer surface of the annular cage (124). Lubrican t is also delivered to the squeeze film damper which serves as the damping medium.
Patent CA-2240854-C (CA)
Inventor: JACQUEMET CHRISTIAN
IPC: C09K23/00
Filed: 1998-07-17
Granted: 2002-12-10
Abstract: The present invention relates to the use of a copolymer, in which at least one of the monomers has a surface-active structure, as a dispersing agent or crushing aid for mineral substances in aqueous suspension, regardless of the nature of the mineral substance.
Patent CA-2248676-C (CA)
Inventor: LIEBESKIND LANNY S
IPC: C07F7/18
Filed: 1997-05-06
Granted: 2003-03-25
Abstract: L'invention se rapporte au produit de réaction d'un organosilane possédant éventuellement un groupe organique non hydrolysable, mais possédant un ou plusieurs groupes hydrolysables, avec un polyol contenant au moins trois groupes hydroxy, deux de ces groupes hydroxy étant séparés par au moins trois atomes intermédiaires. L'invention se rapporte également à des composés d'organosilisane rendus stables à l'eau, à une composition stable à l'eau obtenue à partir du produit ou composé et l'eau, un procédé de traitement de substrat consistant à mettre ce dernier en contact avec le produit, le composé ou la composition sur une durée suffisante pour traiter le substrat, et à un substrat traité sur lequel adhère le produit, le composé ou la composition.
Patent CA-2249034-C (CA)
Title: System and method for using a window mechanism to control multicast data congestion
Inventor: SABNANI KRISHAN KUMAR
IPC: H04L69/40
Filed: 1998-09-29
Granted: 2003-04-15
Abstract: A system and method for using a window mechanism to control transmission of a multicast in a computer network to curb congestion.  In one embodiment, the system includes: (1) a packet monitor that tracks, for each receiver of the multicast, unacknowledged packets transmitted to each receiver and (2) a multicast manager, associated with the packet monitor, that controls transmission of further packets of the multicast to prevent the unacknowledged packets transmitted to any of each receiver from exceeding a maximum number associated with each receiver.
Patent CA-2251742-C (CA)
Title: Drug complex
Inventor: KITAGUCHI NOBUYA
IPC: A61K47/48
Filed: 1997-04-15
Granted: 2001-12-11
Abstract: Disclosed is a drug complex of a drug having a hydroxyl group, which is capable of controlling the rate of the release of the drug therefrom in blood, the drug complex being represented by the following formula (1):  A-B-C (1) wherein A represents at least one carrier selected from the group consisting of saccharides each having a car- boxyl group, polyethylene glycols each having a carboxyl group, aliphatic carboxylic acids each having a carboxyl group, and derivatives thereof each having a carboxyl group; B represents at least one spacer comprised of a compound having a amino group and a carboxyl group; C represents at least one drug having a hydroxyl group, wherein the carrier A is bonded to the spacer B through an amide bond formed between the carboxyl group of the carrier A and the amino group of the spacer B; and the spacer B is bonded to the drug C through an ester bond formed between the carboxyl group of the spacer B and the hydroxyl group of the drug C. The drug complex of the present invention is capable of not only surely controlling the rate of release of the drug therefrom, but also enhancing the transferability of the drug to target tissues and the pharmacological effect of the drug.
Patent CA-2257322-C (CA)
Title: Thiazole derivatives
Inventor: HILPERT KURT
IPC: A61K31/445
Filed: 1998-12-30
Granted: 2003-11-04
Abstract: Compounds of formula I                      as well as pharmaceutically usable salts and esters thereof, wherein R1, R2 and R3 have the significance given in claim 1, inhibit the binding of adhesive proteins to the surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. They can be used in the form of pharmaceutical  preparations in the control or preventon of neoplasms, tumour metastasing, osteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosis following vascular intervention, psoriasis, arthritis, kidney failure as well as infections caused by viruses, bacteria or fungi.
Patent CA-2264822-C (CA)
Title: Cocoa components, edible products having enhanced polyphenol content, methods of making same and medical uses
Inventor: SCHMITZ HAROLD H
IPC: A23L9/10
Filed: 1997-09-08
Granted: 2008-03-25
Abstract: Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.
Patent CA-2266312-C (CA)
Inventor: PALLEY IGOR
IPC: B65D90/02
Filed: 1997-04-11
Granted: 2006-10-17
Abstract: Blast resistant and blast directing container assemblies (11, 12, 13) for receiving explosive articles and preventing or minimizing damage in the event of an explosion. The container assembly (11, 12, 13) comprises a container of blast resistant material and a blast mitigating material (14) located within the container. The container is collapsible for storage when empty. The container assemblies have utility in aircraft, where weight is an important consideration, as cargo holders or containment devices in the passenger cabin. They also are useful as transport devices for hazardous materials such as gunpowder and explosives, e.g., bombs and grenades.
Patent CA-2274149-C (CA)
Inventor: PODDUTURI SUREKHA
IPC: A61K38/02
Filed: 1997-12-09
Granted: 2008-07-15
Abstract: Described are peptides and compounds that bind to and activate the thrombopoietin receptor. Such peptides and compounds are useful in methods for treating haematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labelled peptides and compounds.
Patent CA-2280597-C (CA)
Title: Process for coating the flow channels in a monolithic catalyst carrier with a coating dispersion
Inventor: KRAMPE WILLI
IPC: B05D7/24
Filed: 1999-08-19
Granted: 2008-06-03
Abstract: The invention relates to a process for coating the flow channels in a monolithic, cylindrically shaped catalyst carrier with a coating dispersion, wherein the carrier has two end faces which are connected to each other by flow channels arranged parallel to the axis of the cylinder, by vertically aligning the axis of the cylindrical carrier, placing a predetermined amount of coating dispersion from a storage container on the upper end face of the carrier and drawing the dispersion through the flow channels under suction, removing excess coating dispersion from the flow channels by emptying the flow channels under suction, returning the excess dispersion to the storage container and fixing the dispersion coating by calcination. The process is characterised in that the coating dispersion is drawn through the flow channels under suction at a rate of flow of 0.1 to 1 m/s and that after completion of passage under suction the excess coating dispersion is removed from the flow channels by applying a suction impulse from below, wherein the suction air is drawn through the flow channels under suction at a rate of flow between 40 and 1 m/s and the excess coating dispersion discharged with the air stream is separated from the air stream within a time of less than 100 ms after discharge from the catalyst carrier.
Patent CA-2282816-C (CA)
Title: Self-aligning prefabricated door frame assembly
Inventor: BARR GERALD L
IPC: E06B1/10
Filed: 1999-09-21
Granted: 2006-11-28
Abstract: The invention is a prefabricated door assembly for installation in a rough-in door frame. The assembly includes a pair of vertically extending door jambs having inter-engaging casings and a header unit spanning the upper ends of the door jambs. The header unit includes a header board or jamb having inter-engaging horizontal casings. Both horizontal and vertical casings have pin nails protruding from their tongue portions which engage the jambs lightly during transport and installation prior to final nailing in place. The assembly also includes L-shaped brackets affixed to the upper outer corners which join and fasten the vertical and horizontal jambs together. The assembly may be packaged as a kit, which may include hinges, shins and/or shimming hardware.
Patent CA-2287944-C (CA)
Inventor: JENSEN EARL M
IPC: E21B43/16
Filed: 1997-05-01
Granted: 2006-03-21
Abstract: A method of producing fluids from a subterranean formation (10) through a single well (1) in a network of separate well-bores, comprising the steps of forming a well (1) having a horizontal section (3) located within the formation (10), completing and equipping such well (1) to produce fluids from the formation (10), producing fluids from th e formation through such well (1); forming at least one additional well (2) having a horizontal section (4) located within the formation (10) such that such well (3) is in fluid communication with the first well (1), without intersecting with the horizontal section (3) of the first well (1), and using such additional well (2) as a conduit within the formation to allow and cause fluids contained in the formation which dra in or flow into the horizontal section (4) of such additional well-bore, to flow to and be produced through the first well-bore (1).</SDOA B>
Patent CA-2296213-C (CA)
Title: Distributed subscriber management
Inventor: SKEMER TERRY
IPC: H04L12/28
Filed: 2000-01-14
Granted: 2009-04-14
Abstract: A Distributed Subscriber Management system is disclosed which controls acces s to a network preventing unauthorized traffic through the access network and providing centralized access control between User Networks. The system in accordance with the invention provides controlled access through the use of one of several technologies including user authentication, using PAP, CHAP, RADIUS, TACACS+, or other standard authentication means. The preferred system allows setup maintenance , and tear- down of the user connection and allows users to choose their destination as opposed to tying a user to a single destination. The system also preferably provides fo r the administration of the assignment and release of network addresses. The invention also provides a Distributed Subscriber Management (DSM) method for performing use r authentication for an external network at an access control node, which external network is connected to the access control node by means of an Access Network while the access control node is connected to a plurality of User Networks. The method includ es the steps of receiving a connection request from a user located on one of the User Networks; interrogating the user for userid and password information; encrypting the userid and password information; transmitting the encrypted information, via the Access network, to an authentication server attached to one of a plurality of external networks ; decrypting the information at the authentication server; and transmitting an authentication message from the authentication server of the external network to the access control node via the Access Network. The preferred method includes the additional step of challenging al l data leaving the access control node. The authentication server of the external network normally employs one of Radius, PAP, CHAP, and TACACS or TACACS+.
Patent CA-2297473-C (CA)
Inventor: TAKAHIRO NUMAI
IPC: G01C19/64
Filed: 2000-01-21
Granted: 2003-11-18
Abstract: A gyro comprises a first laser adapted to generate a first laser beam propagating in a direction as a main mode of operation, a second laser adapted to generate a second laser beam propagating in a direction as a main mode of operation. The gyro may have a beat signal detection means and a photodetector for receiving the first and second laser beams. The first laser beam and the second laser beam have different respective oscillation frequencies and interfering with each other.
Patent CA-2298238-C (CA)
Inventor: CURATOLO WILLIAM JOHN
IPC: A61K31/44
Filed: 2000-02-09
Granted: 2005-10-25
Abstract: Controlled release dosage forms for low solubility drugs are disclosed wherein an amorphous solid dispersion of the drug is coated with a non-dissolving and non-eroding coating that controls the influx of water to the core so as to cause extrusion of a portion of the core, as well as a method of treating a disease or disorder comprising administering such dosage form to a person.
Patent CA-2302360-C (CA)
Title: Fluorination of proteins and peptides for f-18 positron emission tomography
Inventor: GRIFFITHS GARY L
IPC: A61K51/10
Filed: 1998-09-03
Granted: 2005-11-15
Abstract: Thiol-containing peptides can be radiolabeled with fluorine-18 (F-18) by reacting a peptide comprising a free thiol group with an F-18-bound labeling reagent which also has a group that is reactive with thiols. The resulting F-18-labeled peptide s may be targeted to a tissue of interest using bispecific antibodies or bispecific antibody fragments having on arm specific for the F-18-labeled peptide or a low molecular weight hapten conjugated to the F-18-labeled peptide, and another arm specif ic to the targeted tissue. The targeted tissue is subsequently visualized by clinincal positron emission tomography. The method for radiolabeling thiol-containing peptides with fluorine-18(F-18), comprises reacting a peptide comprising a free thiol grou p with a labelling reagent having the general formula 18F-(CH2)m-CR1,R2-(CH2)n-X, wherein: n is 0, 1 or 2; m is 0, 1 or 2; and n+m is 0, 1, or 2; X is selected from the group consisting of hydroxyl, cyano, iodide, bromide, chloride, azide, tosylate, mesylate, nosylate, triflate, unsubstituted maleimide, maleimide substituted with one or two alkyl groups, and 3-sulfo-maleimide; and R1 and R2 are the same or different and are selected from the group consisting of iodide, bromide, chloride, azide, tosylate, mesylate, nosylate, triflate, hydrogen, -CONH2, carboxyl, hydroxyl, sulfonic acid, tertiary amine, quaternary ammonium, unsubstituted maleimide, maleimide substituted with on or two alkyl groups, 3-sulfo-maleimide, unsubstituted alkyl, substituted alkyl, -COOR',-CONR'2, or COR', wherein the substituents of the substituted alkyl groups are selected from the group consisting of -CONH2, carboxyl, hydroxyl, sulfonic acid, tertiary amine and quaternary ammonium and wherein R' is a C1-C6 alkyl or phenyl.