baber/WOPTO huggingface dataset:
Patent EA-201992359-A1 (EA)
Title: Трициклические соединения в качестве ингибиторов киназы гликогенсинтазы-3 (gsk3) и их применение
IPC: A61K31/4745
Filed: 2018-04-05
Abstract: Настоящее изобретение относится к соединениям формулы (I) и их солям, сольватам, гидратам, полиморфам, сокристаллам, таутомерам, стереоизомерам, меченным изотопами производным и их пролекарствам. Предложенные соединения могут быть полезны для ингибирования киназ, например киназы гликогенсинтазы-3 (GSK3). Предлагаемые соединения способны селективно ингибировать GSK3 по сравнению с GSK3 и/или другими киназами. Настоящее изобретение дополнительно относится к фармацевтическим композициям, наборам и способам применения, каждый из которых включает указанные соединения. Соединения, фармацевтические композиции и наборы могут быть полезными для лечения заболеваний, связанных с аберрантной активностью GSK3 (например, синдрома ломкой Х-хромосомы, синдрома дефицита внимания с гиперактивностью (СДВГ), судорожных припадков у детей, умственной отсталости, диабета, острого миелоидного лейкоза (ОМЛ), аутизма и психиатрического расстройства).
Patent EA-201992630-A1 (EA)
Title: Способы лечения заболеваний глаз антагонистами aplnr и ингибиторами vegf
IPC: C07K14/71
Filed: 2018-05-04
Abstract: Изобретение представляет способы лечения, профилактики или снижения тяжести заболевания глаз. Способы по данному описанию включают в себя введение субъекту, нуждающемуся в этом, терапевтической композиции, содержащей антагонист APLNR, такой как анти-APLNR антитело, в сочетании с антагонистом фактора роста эндотелия сосудов (VEGF) (например, афлиберцепт).
Patent EA-202091100-A1 (EA)
Title: Модульная система переработки
IPC: C10G53/16
Filed: 2018-11-09
Abstract: Изобретение относится к системе переработки, содержащей по меньшей мере одно устройство повышения давления; по меньшей мере одно устройство разделения; по меньшей мере одну секцию конверсии; по меньшей мере один клапанный узел между по меньшей мере одним устройством повышения давления и по меньшей мере одной секцией конверсии; по меньшей мере один клапанный узел между по меньшей мере одной секцией конверсии и по меньшей мере одним узлом разделения; где секция конверсии содержит по меньшей мере два параллельных узла конверсии; где каждый узел конверсии содержит по меньшей мере одно нагревательное устройство, по меньшей мере одно реакторное устройство и по меньшей мере одно охлаждающее устройство.
Patent EA-202092200-A1 (EA)
Title: Индуцирующие т-клетки комбинации композиций вакцин и их применение
IPC: A61K39/12
Filed: 2019-04-04
Abstract: В настоящем документе представлены комбинации вакцин и способы усиления индуцированного антигенспецифическими Т-клетками ответа у нуждающегося в этом субъекта. Способы объединяют системную вакцинацию с первой композицией, содержащей нереплицирующийся вирусный вектор, кодирующий антиген или иммуноген, содержащий один или более эпитопов CD8+ Т-клеток; и/или второй композицией с мицеллами, содержащими связанные с фторуглеродом пептиды, причем каждый пептид, связанный с фторуглеродом, характеризуется i) длиной от 15 до 75 аминокислотных остатков; ii) происхождением от антигена или иммуногена первой композиции и iii) содержанием одного или более эпитопов CD8+ Т-клеток первой композиции из антигена или иммуногена для индукции антигенспецифических CD8+ Т-клеток; и, необязательно, третьей композицией, содержащей композицию иммуномодулятора.
Patent EA-202092981-A1 (EA)
Title: Антитела к l1cam и их применение
IPC: C07K16/28
Filed: 2019-06-27
Abstract: В данном изобретении предложены антитела, которые специфически связываются с L1CAM, и композиции, содержащие такие антитела. В данном документе также предложены способы предотвращения или лечения заболеваний или патологических состояний, которые включают опухоль, с использованием антител к L1CAM.
Patent EA-202191124-A1 (EA)
Title: Лекарственная форма для лечения и профилактики гриппа и орви
IPC: A61P31/12
Filed: 2019-10-22
Abstract: Изобретение относится к химико-фармацевтической промышленности и медицине и касается новой жидкой лекарственной формы для перорального введения для лечения и профилактики гриппа и ОРВИ, содержащей 2-(имидазол-4-ил)этанамид пентандиовой-1,5 кислоты в эффективном количестве и вспомогательные вещества.
Patent EA-202191355-A1 (EA)
Title: Стабилизированные f-белки rsv до слияния
Filed: 2019-11-12
Abstract: Изобретение относится к стабильным F-белкам респираторно-синцитиального вируса (RSV) до слияния, к иммуногенным композициям, содержащим указанные белки, и к их применениям для профилактики и/или лечения инфекции, вызванной RSV.
Patent EA-202192135-A1 (EA)
Title: Гербицидные смеси
Filed: 2020-02-04
Abstract: В изобретении предусматривается композиция, содержащая (A) соединение формулы (I)где R1 представляет собой метил или метокси, R2 представляет собой водород, метил или этокси и A представляет собой замещенную гетероарильную группу, или его N-оксид, или солевую форму и (B) один или несколько дополнительных гербицидов; а также применение таких композиций в осуществлении контроля растений или подавлении роста растений.
Patent ES-2190376-A1 (ES)
Title: Machine for automatic resining of flat boards for construction, comprises chassis leaning on both supports, provided with driving equipment and reducer from which rotary shaft is projected
Inventor: MUNOZ ALBINANA JOSE
IPC: B28B11/04
Filed: 2001-12-14
Abstract: Machine to apply resin automatically to plates or flat pieces in the construction industry. This is installed on the bed of a roller conveyor and supported by a set of vertically-moving, telescopic columns, which support the motor for driving the resin application device. This is able to regulate the uniform spread of resin over the surface of the plate or tile, automatically fed by a vertical pipe that is primed by a set of electrically-operated valves with a controlled, fixed amount, proportional to the size of the tile or plate by a bar sensor in the resin application device. It is driven by the passing of the tiles, which are moved by the conveyor.< IMAGE >The fixed portion (5) of the columns (3,4) is provided which rotates over the lower end (7) on the support foot (8) and a movable portion (6) is guided telescopically in the fixed portion of the column. A chassis (41) leaning on both supports, is provided with a driving equipment (20) and reducer (21) from which the rotary shaft (22) is projected.
Patent ES-2215440-A1 (ES)
Title: Resin compound based dental cavity sealing kit includes cooled composite blocks in a base, for polymerisation and compensation of the accompanying shrinkage
Inventor: DE LA TORRE MORENO FRANCISCO J
IPC: A61C5/50
Filed: 2002-02-01
Abstract: The resin compound based dental cavity sealing kit has small cooled composite blocks introduced into a base applied to the dental cavity, for polymerisation. Once the cooled material reaches mouth temperature (37 degrees C) it expands, partly compensating the polymerisation contraction, with decrease in the polymerisable material consumption.
Patent ES-2214102-A1 (ES)
Title: System for evacuating smoke and hot gases in industrial establishments of e.g. building, has retaining element releasing parallelogram mechanism, cover covering passages, and frame mounted on window of profiled sheet
Inventor: CARRANZA GARCIA ANTONIO
IPC: F24F7/02
Filed: 2002-07-05
Abstract: The system has two stiffeners formed by two angle profiles (9, 10) that are fixed in a frame (3) and a profiled sheet (5), which is connected with upstream and downstream end portions of a frame assembly (1). The frame assembly and a cap assembly (2) are linked together. A cover (16) is attached to a rotating mechanism. A parallelogram mechanism is mounted on a frame body (19), which is fixed at a top part of the frame. A retaining element releases the parallelogram mechanism. The cover covers passages (4, 6). The frame is mounted on a window of the profiled sheet.
Patent ES-2232285-A1 (ES)
Title: Floating wind turbine, has shaft provided with submerged portion of inverted stem unit, set of floating units are provided with inverted stem unit, and air securing units attached with stem
Inventor: CASAS TOJO CASTOR
IPC: F03D13/25
Filed: 2003-05-13
Abstract: The turbine (9) has a shaft (1) provided with a submerged portion of an inverted stem unit (3). A set of floating units (4) are provided with the inverted stem unit. The floating units are connected at a base of a stem (10). Air securing units are attached with the stem.
Patent ES-2239878-A1 (ES)
Title: Fusion protein containing a dimerisation domain and an autotransporter domain
Inventor: FERNANDEZ HERRERO LUIS ANGEL
IPC: C12N1/02
Filed: 2003-06-06
Abstract: The invention relates to fusion proteins containing the beta -autotransporter domain of the IgA protease of Neisseria gonorrhoea and the leucine zippers of the Jun and Fos eukaryotic transcription factors. The invention also relates to a method of generating the aforementioned proteins and to the uses of same.
Patent ES-2247890-A1 (ES)
Title: Optical metrology method which is used to determine the three-dimensional topography of a hole
Inventor: LAGUARTA BERTRAN FERRAN
IPC: G01B11/25
Filed: 2003-10-10
Abstract: An optical metrology method for conical orifices according to the invention consists in arranging the object having the orifice under a microscope with the greater diameter opening facing illumination means and centring it in the field of view of observation means and bringing it into focus using wide-field illumination on the smaller diameter opening so as to measure its diameter and major defects. Subsequently, the focus plane is changed and the contour of the orifice is measured by projecting a sequence of patterns measuring the position of the points along the contour of the orifice when the images of the projected pattern and their reflection on the inner walls of the orifice are superimposed on the plane of the camera of the apparatus. The method is repeated and the data describing the contours measured in different planes are processed to obtain a three-dimensional geometrical representation and the characteristic parameters of the inner topography of the orifice.
Patent ES-2273535-A1 (ES)
Title: Hydraulic vibratory system for harvesting of fruit trees has rubber blocks to prevent transmission of vibrations to tree whose trunk is held by clamps
Inventor: TRASSIERRA PLAZA ANA MARIA
IPC: A01D46/26
Filed: 2004-05-05
Abstract: A circular mass moves either by revolving about a vertical axis connected to a hydraulic motor or linearly moving towards or away from the axis on a horizontal plane to vary the amplitude of vibration. Movement is effected by driving two bowlers at one end of the axis through a hydraulic circuit. Clamps hold the tree trunk while rubber blocks prevent the vibrations from being transmitted to the tree.
Patent ES-2289944-A1 (ES)
Title: Mechanism for massaging the lower parts of a user's legs
Inventor: CANTO GARCIA ENRIQUE
IPC: A61H15/00
Filed: 2006-07-21
Abstract: It comprises two pairs of massaging discs (1a, 1b) connected to an actuating mechanism (4) and joined in a fixed and eccentric manner and in convergent inclined planes to respective rotary axes (A, B), the discs being designed for massaging opposite sides of the lower part of a leg (3a, 3b) at least one clutch mechanism (5) with an internal housing (6) that comprises two stop elements (6a, 6b), a channel (6c) of arcuate vertical cross section between said stop elements (6a, 6b) and a projection (6d) between the stops (6a, 6b) an intermediate massaging element (15, 18, 21) whose massaging surface is at least semicylindrical and is actuated by performing a transverse movement over the surface to be massaged an intermediate massaging element consisting of a plate (27) provided with vibration means for applying a vibrating massage and means for regulating the distance between the discs (1a, 1b 2a, 2b), in order to adapt to the size of the part to be massaged.
Patent ES-2302452-A1 (ES)
Title: Aryl thioether derivatives synthesizing method involves reaction between aryl and thiol group, where reaction takes place in presence of copper compound and diamine derivative using water as solvent
Inventor: CARRIL GARCIA MONICA
IPC: C07C321/30
Filed: 2006-11-24
Abstract: The method involves reaction between aryl and thiol group. The reaction takes place in the presence of a copper compound and a diamine derivative using water as a solvent. The derivatives include 6 to 18 carbon aryl or 2 to 18 carbon heteroaryl with 1 to 4 heteroatoms selected from nitrogen, oxygen and sulphur, replaced with one or multiple substituents selected from alkyl or hydroalkyl, alkoxy, acyl, amino, hydroxy, nitro, halogen and aryl group.
Patent ES-2308910-A1 (ES)
Title: Biaxial solar tracker
Inventor: GRANT THOMAS
IPC: F24S50/20
Filed: 2006-12-05
Abstract: The invention comprises a fixed platform (1) bearing a circular rail (2), supporting rolling elements to which is attached a mobile frame (4) with a sloping structure (5) which holds a number of solar panels (P), grouped in rows (H), the panels (P) of each row (H) being connected to corresponding support shafts (E1-E4), supported on said sloping structure (5), and means for moving the frame (4) and shafts (E1-E4) in accordance with a predetermined configuration. The frame (4) includes a base (B) with attached thereto said rolling elements and the sloping structure (5) is raised above said base (B), at a distance from the fixed platform (1) and formed by two supporting beams (6, 7) that delimit an oblique plane and are separated from each other by a distance greater than the diameter of the rail (2).
Patent ES-2304882-A1 (ES)
Title: Method and system of detection of viewing of objects inserted in web pages
Inventor: ALMENAR BELENGUER PEDRO
IPC: G06Q30/00
Filed: 2007-04-10
Abstract: The invention relates to a method and system for detecting the display of objects inserted in web pages. The method comprises downloading (12) a web page from a web server (2) to a web browser of a customer, said web page including information regarding a detection function for detecting the display on the screen of the web browser of the objects inserted in the web page downloading (14) the objects to be inserted in the web page from an inserted object provider server (3) to the customer's web browser inserting said objects in the web page associating the detection function with the inserted objects the web browser sending (15) a message with the identifier of the displayed object to a hit measurement server (4) each time the detection function detects that an object has been correctly displayed monitoring the displays of said objects in the hit measurement server (4).
Patent ES-2340118-A1 (ES)
Title: Biomass concentration measurement device and method and use of an electronic chip element for measuring said biomass concentration
Inventor: MUNOZ BERBEL XAVIER
IPC: C12M1/34
Filed: 2008-01-16
Abstract: The invention relates to a device for measuring the biomass concentration of a medium, including: means for measuring the change in electric impedance produced by the presence of biomass, and control and processing means for determining the biomass concentration from said means in order to measure the impedance change. The invention is characterised in that the impedance change measurement means include at least two electrodes having a suitable configuration to allow the measurement of the capacitance change of the double electric layer of the electrode/solution interface, produced by the electrostatic adhesion of the biomass. The invention is also characterised in that the processing and control means determine the biomass concentration from a calibration curve that correlates the capacitance change value with the biomass concentration. The invention also relates to the method used to measure the biomass concentration of the medium using impedance change measurement means. The invention further relates to the use of an electronic chip element for measuring biomass concentration.
Patent ES-2335562-A1 (ES)
Title: Heteromolecular metal-humic (chelate) complexes
Inventor: GARCIA-MINA FREIRE JOSE MARIA
IPC: C08H7/00
Filed: 2008-02-19
Abstract: Heteromolecular metal-humic organic complexes of the type: (A)n-(Metal)x-(B)m where A is one or several humic complexes which may be totally or partially sulfonated or may have been treated with an amine in order to protect the carboxylic groups from interacting with polyvalent cations, and B is a non-humic complexing (organic chelating agent) compound, the biological and chemical stability whereof allows for protection of the metal and the multitoothed molecule involved in the complex against degradation phenomena, both chemical and microbiological, having the beneficial effect of humic acid, as an effective plant growth and nutrition stimulant and as a metabolic and immune system activator in animals and humans.
Patent ES-2364309-A1 (ES)
Title: Transparent electrode based on combination of transparent conductive oxides, metals and oxides
Inventor: PRUNERI VALERIO
IPC: C23C14/00
Filed: 2010-02-19
Abstract: The invention relates to an electrode comprising a transparent conductive oxide (TCO) and an ultra thin metal film (UTMF) deposited on the TCO. In addition the UTMF is oxidized or covered by an oxide layer. In this way the underlying TCO is protected/compatible to other materials and the loss of transparency is reduced.
Patent ES-2386885-A1 (ES)
Title: Hydrophobic/hydrophilic molecular switch, device containing said switch and method for controlling surface hydrophobicity
Inventor: VECIANA MIRO JAUME
IPC: G01N33/48
Filed: 2011-02-08
Abstract: The switch comprises: a solid substrate having, anchored on the surface thereof, functionalized molecules of polychlorotriphenylmethyl (PTM) in a radical or anion oxidation state, such that said molecules form a hydrophobic surface, a hydrophilic surface or a surface with hydrophobic areas and hydrophilic areas and means for reversibly changing the oxidation state from radical to anion or vice versa locally on the substrate. The invention also relates to the memory device containing said switch, as well as to a module for conditioning the signal and a module for processing same. The switch and the device containing the switch are particularly suitable for use in the field of microfluidics, as biomolecule dispensers or biosensors, in the production of tags or markers or in the field of self-cleaning surfaces.
Patent ES-2444711-A1 (ES)
Title: Method and device for determining chloride migration coefficients of partially water-saturated concretes
Inventor: ANTON GIL CARLOS
IPC: G01N27/26
Filed: 2012-07-26
Abstract: The invention relates to a device and method for determining chloride migration coefficients, comprising a first ionic conducting gel having an NaCl matrix (2, 22), in which: the first ionic conducting gel is in contact with a concrete test piece (3, 23) and is connected via an electrode (1, 21) to the negative pole of a power supply and the electrical circuit is closed with a second ionic conducting gel having an NaNO 3 matrix (4, 24) connected via a second electrode (1, 21) to the positive pole of the power supply. A similar arrangement, in which the ion in the matrix is replaced with other types of ions, allows the introduction of species and facilitates the movement thereof through the concrete for other purposes, such as, for example, the incorporation of cationic inhibitors.
Patent ES-2530915-A1 (ES)
Title: Bioinspired antifungal systems
Inventor: SEGURA TANIA
IPC: A01N37/12
Filed: 2013-06-14
Abstract: Bioinspired antifungal systems. The invention relates to novel systems based on substrates containing covalently bonded ergosterol molecules that can comprise antifungal compounds imitating the joining of the antifungal agent to the wall of the fungi. When the systems of the invention loaded with antifungal agents are in the presence of fungi, the transfer process is accelerated as a competition is established for the antifungal agent between the ergosterol of the systems of the invention and the ergosterol of the wall of the fungi. The systems according to the invention are useful for the prevention of colonisation by fungi and/or for the treatment of infections by fungi, in applications such as systems for the release of antifungal active substances, and packagings or coverings for work surfaces.
Patent HR-P20201526-A1 (HR)
Inventor: JUROŠ IVO
IPC: E02D29/14
Filed: 2020-09-23
Abstract: Poklopac šahte (1) sadrži hidrauličku instalaciju (20) koja je odgovorna za zaključavanje poklopca šahte na način da se hidrauličkim agregatom preko hidrauličkih utičnica (13) hidrauličkim cilindrima (3) potiskuje elastični opružni natezač (5) i klin (6) u utore na obruču šahte (1). Otključavanje se vrši na način da se hidrauličkim agregatom i hidrauličkim cilindrima (3) uvlače elastični opružni natezač (5) i klin (6) u unutrašnjost poklopca šahte (2). Da bi hidraulički agregat mogao spojiti na hidrauličke utičnice (13), potrebno je otvoriti poklopac (10), a to je moguće napraviti pomoću kartice koja se stavlja u utor za karticu (15) i nakon toga elektronički uređaj u kutiji za elektroniku (16) šalje signal aktuatoru (7) koji ima ulogu otključavanja i zaključavanja poklopca (10). Otključavanje je moguće samo ako je kartica registrirana, u protivnom, aktuator (7) neće dobiti signal za otključavanje.The manhole cover (1) contains a hydraulic installation (20) which is responsible for locking the manhole cover in such a way that the hydraulic unit pushes the elastic spring tensioner (5) and the wedge (6) into the grooves of the shaft ring (1) through the hydraulic sockets (13) by hydraulic cylinders (3). Unlocking is done by pulling the elastic spring tensioner (5) and the wedge (6) into the interior of the manhole cover (2) with the hydraulic power unit and hydraulic cylinders (3). In order to be able to connect the hydraulic power unit to the hydraulic sockets (13), it is necessary to open the cover (10), which can be done with a card inserted in the card slot (15) and then an electronic device in the electronics box (16) sends a signal to the actuator (7) which has the role of unlocking and locking the cover (10). Unlocking is only possible if the card is registered, otherwise the actuator (7) will not receive an unlock signal.
Patent HR-P20201924-A1 (HR)
Inventor: ŠKULIĆ IVAN
IPC: F02D15/02
Filed: 2020-12-02
Abstract: Izum se odnosi na novi sistem pretvorbe linearnog kretanja klipa (2) u rotaciono kretanje koljenčastog vratila (7) posredstvom polužnog mehanizma, koji se sastoji od stapajice (3), specifične poluge (4) i ojnice (5). Poluga (4) je na jednom svom kraju (u točki C) spojena svornjakom sa ojnicom (5), dok je drugim svojim krajem vezana svornjakom za kućište motora (u točki A). Stapajica (3) spojena je jednim krajem za klip (2), dok je drugim krajem spojena za polugu (4) (u točki spajanja B). Pri tome je navedena ojnica (5) svojim drugim krajem vezana za rukavac (6) koljenastog vratila(7). Pod djelovanjem klipa (2) u fazi ekspanzije, poluga (4) se zakreće oko točke A pri čemu prenosi silu potiska klipa (2) na ojnicu (5). Navedena ojnica (5) spojena je svojim drugim krajem na rukavac (6) te djeluje na zakretanje koljenastog vratila (7).The invention relates to a new system for conversion of linear piston movement (2) in rotary crankshaft movement (7) by levering mechanism, which consists of a rod (3), a specific lever (4) and a connecting rod (5). The lever (4) is connected at one end (at point C) with a connecting rod bolt (5), while at the other end it is connected with a bolt to the motor housing (at point A). The piston rod (3) is connected at one end to the piston (2), while the other end is connected to the lever (4) (at the connection point B). In this case, said connecting rod (5) is connected at its other end to the sleeve (6) of the crankshaft (7). Under the action of the piston (2) in the expansion phase, the lever (4) rotates around point A, transmitting the thrust force of the piston (2) to the connecting rod (5). Said connecting rod (5) is connected at its other end to the sleeve (6) and acts to rotate the crankshaft (7).