baber/WOPTO huggingface dataset:
Patent AU-692292-B2 (AU)
Title: Methods of preparing organs for cryopreservation and subsequent transplantation
Inventor: FAHY GREGORY M
IPC: A01N1/02
Filed: 1995-08-11
Granted: 1998-06-04
Abstract: The invention relates to the field of organ and tissue perfusion. More particularly, the present invention relates to a method for preparing organs, such as the kidney and liver, for cryopreservation through the introduction of vitrifiable concentrations of cryoprotectant into them. To prepare the organ for cryopreservation, the donor human or animal, is treated in the usual manner and may also be treated with iloprost, or other vasodilators, and/or transforming growth factor  beta 1. Alternatively, or additionally, the organ which is to be cryopreserved can be administered iloprost, or other vasodilators, and/or transforming growth factor  beta 1 directly into its artery. The invention also relates to preparing organs for transplantation by a method for the removal of the cryoprotectant therefrom using low (such as raffi nose, sucrose, mannitol, etc.), medium (such as agents with intermediate molecular weights of around 600-2,000) and high (such as hydroxyethyl starch) molecular weight agents osmotic buffering agents. The invention is also directed to new post-transplantation treatments such as the use of transforming growth factor  beta 1, N-acetylcysteine and aurothioglucose.
Patent AU-617778-B2 (AU)
Title: Sonic generator
Inventor: NYBERG CHRISTOPHER A
IPC: B02C17/08
Filed: 1989-03-31
Granted: 1991-12-05
Abstract: A sonic generator comprises a resonant bar (11), a housing (20) and magnetic excitation (13) units connected between the resonant bar (11) and the housing (20). The magnetic excitation units (13) are connected to the bar (11) at highly stressed points using a mounting connection (14) which is a sleeve having an inside diameter slightly greater than the outside diameter of the bar (11). A resilient elastomer (21) such as urethane is mounted between the sleeve (14) and the resonant member (11). The sonic generator may be used for grinding purposes and, in particular, may be used to grind material exceptionally fine with reduced power consumption. The bar (11) is substantially unrestrained so as to allow substantially free vibration. <IMAGE>
Patent AU-784761-B2 (AU)
Title: Biallelic markers related to genes involved in drug metabolism
Inventor: BLUMENFELD MARTA
IPC: C12Q1/68
Filed: 2000-03-24
Granted: 2006-06-08
Abstract: The invention provides polynucleotides including biallelic markers derived from genes involved in the biotransformation of xenobiotics such as drugs and from genomic regions flanking those genes. Primers hybridizing to regions flanking these biallelic markers are also provided. This invention also provides polynucleotides and methods suitable for genotyping a nucleic acid containing sample for one or more biallelic markers of the invention. Further, the invention provides methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype.
Patent AU-668384-B2 (AU)
Title: Controlled release ACTH containing microspheres
Inventor: KHAN M AMIN
IPC: A61K38/35
Filed: 1993-03-12
Granted: 1996-05-02
Abstract: ACTH polymeric controlled release systems are described wherein the ACTH retains good biological activity and is released over an extended period of time following administration by injection. In the preferred embodiment, the ACTH polymeric microspheres are made using very cold temperatures to freeze the polymer-ACTH mixtures into polymeric microspheres with very high retention of biological activity and material. Sustained release of biologically active ACTH is achieved when the microspheres are tested in vitro, extending over a period of greater than one day to several months. Altered release can be achieved by inclusion of degradation modifiers, pore forming agents, and stabilizers of the ACTH.
Patent AU-668581-B2 (AU)
Title: Continuous ultrasonic devulcanization of vulcanized elastomers
Inventor: ISAYEV AVRAAM
IPC: B29K105/24
Filed: 1993-06-16
Granted: 1996-05-09
Abstract: This invention relates to a continuous ultrasonic method for breaking the carbon-sulfur (C-S), sulfur-sulfur (S-S), and if desired, carbon-carbon (C-C) bonds in a vulcanized elastomer. It is well known that vulcanized elastomers having a three-dimensional chemical network, cannot flow under the effect of heat and/or pressure. This creates a huge problem in the recycling of used tires and other elastomeric products. Through the application of certain levels of ultrasonic amplitudes in the presence of pressure and optionally heat, the three-dimensional network of vulcanized elastomer can be broken down. As a most desirable consequence, ultrasonically treated cured rubber becomes soft, thereby enabling this material to be reprocessed and shaped in a manner similar to that employed with uncured elastomers.
Patent AU-2001246519-B2 (AU)
Title: Process and apparatus for the production of a detergent bar
Inventor: MANI SUDHIR
IPC: C11D13/16
Filed: 2001-03-29
Granted: 2004-01-15
Abstract: In an apparatus and process for manufacturing a detergent bar, the bar comprises a first distinct zone comprising a first component and at least a second distinct zone comprising a second component. In an injection step, the first and second components are injected into the mould cavity via nozzle means having a first orifice through which the first component is injected. The second component is injected through a second orifice of the nozzle means. The first and second components solidify in the cavity to form the bar. The interface between the zones may be non-planar and/or such that the zones cannot be separated by a unidirectional cut. The first and second zones may respectively comprise detergent and a benefit agent. The first and second zones may differ in texture.
Patent AU-757616-B2 (AU)
Title: Microbial arachidonic acid (ARA) for use in marine feed
Inventor: BEUDEKER ROBERT FRANCISCUS
IPC: A23K1/18
Filed: 1999-06-17
Granted: 2003-02-27
Abstract: A marine feed composition is described comprising microbially derived arachidonic acid (ARA) or ARA in the form of a triglyceride. The ARA is suitably produced by a fungus, such as of the genus Mortierella, although the feed composition itself is free of microbial cells. These forms of ARA have been found to give better growth and pigmentation promotion in marine organisms (shrimps and fish) than corresponding phospholipid forms of ARA from fish oil. The ARA can be in the form of an oil, e.g. an oil-in-water emulsion or may first be fed to larvae, rotifers or nauplii which are themselves included in a composition as "live" feed for larger organisms.
Patent AU-670814-B2 (AU)
Title: Foundry mixes containing a polyether polyol and their use
Inventor: CARPENTIER WILLIAM G
IPC: C08L75/00
Filed: 1993-09-01
Granted: 1996-08-01
Abstract: This invention relates to foundry mixes which comprise a dry foundry aggregate and a polyurethane-forming foundry binder. The binder components include a polyether polyol component and an organic polyisocyanate component which is cured with a liquid tertiary amine catalyst. The foundry mixes are used to prepare foundry shapes made from foundry mixes by a no-bake process. The resulting foundry shapes are used to cast metal parts from ferrous and non ferrous metals.
Patent AU-674546-B2 (AU)
Title: Hydrogel laminate, bandages and composites and methods for forming the same
Inventor: KUNDEL NIKHIL K
IPC: A61L15/60
Filed: 1993-12-14
Granted: 1997-01-02
Abstract: The present invention provides processes by which a polymeric hydrogel can be securely adhered to a substrate to form a hydrogel laminate with greatly improved delamination resistance. The laminate is formed by casting onto a polymeric adhesive-coated substrate an aqueous solution of hydrophilic polymer, then exposing this composite to ionizing radiation which cross-links the hydrophilic polymer to form a hydrogel and also induces copolymerization of the hydrophilic polymer and the adhesive polymer.
Patent AU-773610-B2 (AU)
Title: New ATPase assay
Inventor: WHITE PETER
IPC: C12Q1/34
Filed: 2000-06-15
Granted: 2004-05-27
Abstract: The present invention uses the principle that phosphomolybdate binds to hydrophobic surfaces to isolate the phosphomolybdate complex from other phosphate-containing molecules and further uses the SPA concept to bring a radiolabeled phosphomolybdate complex in close contact with a scintillant for measurement by scintillation counting. Generally, the present invention provides an assay for detecting and measuring the amount of orthophosphate (Pi) in an aqueous reaction mixture, wherein the amount of Pi released is separated from the reaction mixture by: adding a solution of molybdate to the reaction mixture to form a phosphomolybdate complex; and contacting the phosphomolybdate complex with a hydrophobic surface, wherein the surface is capable of being separated from the aqueous reaction mixture to allow measurement of the Pi. Particularly, this invention provides an assay for measuring the ATPase activity of enzymes, more particularly, the HPV E1 helicase.
Patent AU-581967-B2 (AU)
Title: Cross-linkable extrudable composition
Inventor: HOWELL BARRY GEORGE
IPC: C08K3/22
Filed: 1986-02-05
Granted: 1989-03-09
Abstract: A flame-retardant cross-linkable polymer composition for extrusion which is capable of producing non-porous products comprises: at least one flame-retardant filler of the class that evolve substantial amounts of bound water on heating at temperatures above a value Td that lies in the range 120 DEG -250 DEG  C.; a compatible ethyelene copolymer base in which the filler is dispersed; a hydrolysable unsaturated silane; and a free-radical grafting initiator having a half-life of less than 10 minutes at a temperature 25 DEG  C. below Td.
Patent AU-649611-B2 (AU)
Title: Bicycle suspension system
Inventor: KNAPP THOMAS D
IPC: B62J1/06
Filed: 1990-04-18
Granted: 1994-06-02
Abstract: The invention comprises a system for a bicycle or similar vehicle to allow shock isolation at the location of the seat or handle bar mounting or other locations. The suspension system includes a hydraulically actuated system as well as a variable rate progressive dampening assembly. The hydraulic fluid is also utilized to lubricate the moving portions of the system to promote proper function and extend the useful life thereof. The system also has a variable spring preload to accommodate different sized riders. The system is cost effective and yet extremely durable and may be retrofit for use with existing bicycles.
Patent AU-675473-B2 (AU)
Title: Moisture-hardening polyurethane fusion adhesive
Inventor: HEIDER ROLAND
IPC: C09J5/06
Filed: 1993-11-16
Granted: 1997-02-06
Abstract: PCT No. PCT/EP93/03216 Sec. 371 Date May 25, 1995 Sec. 102(e) Date May 25, 1995 PCT Filed Nov. 16, 1993 PCT Pub. No. WO94/12552 PCT Pub. Date Jun. 9, 1994The hot-melt adhesive of the invention includes A) at least one polyurethane prepolymer of a) at least one polyisocyanate, in particular, toluene diisocyanate and/or MDI, b) at least one polyalkylene glycol at a concentration of more than 10% by weight based on total hot-melt adhesive, in particular, polypropylene glycol, c) at least one polyester glycol, preferably of at least two polyester glycols having different glass transition temperature, and B) optional additives such as d) a resin, particularly a hydrocarbon resin, and e) a stabilizer, particularly toluenesulfonyl isocyanate. Preferably, the hot-melt adhesive has a melt viscosity ranging from 10 to 300 Pa.s at 130 DEG  C. The PU prepolymer has only one single Tg in the DSC diagram. The hot-melt adhesive is notable for its high creep resistance with similarly high initial and final strength. Thus, it is predominantly used in the shoe industry, particularly in coating machines integrable in the shoe production line not including a pre-crosslinking stage using steam or a drying channel. Preferably, the hot-melt adhesive is produced using the single step process.
Patent AU-531556-B2 (AU)
Title: Tripeptides
Inventor: GOLDSTEIN GIDEON
IPC: A61K38/22
Filed: 1980-03-11
Granted: 1983-08-25
Abstract: There are disclosed new biological active polypeptides:wherein A is deamino-LYS or LYS; X is a suitable neutral aliphatic amino acid residue; e.g., one selected from the group consisting of SER, ALA, 2-Me-ALA, GLY, LEU, THR, D-SER, D-ALA, D-THR, allo-THR, D-LEU, and SAR; B is GLN-R', decarboxy-GLN, orand R' is a substituent which does not substantially affect the biological activity of the tripeptide.These polypeptides have the capability of inducing the differentiation of T lymphocytes as measured by the acquisition of the thymic differentiation antigen Th-I, as well as B-lymphocytes as measured by the acquisition of the differentiation antigen Bu-i. The polypeptides are thus useful in thymic function and immunity areas such as in treatment for congenital absence of thymus. Also provided are therapeutic compositions and methods for use of the polypeptides.
Patent AU-624958-B2 (AU)
Title: A process for the continuous manufacture of wall elements and an installation which utilizes such a process
Inventor: EYNDE J VAN DEN
IPC: E04C2/52
Filed: 1990-06-05
Granted: 1992-06-25
Abstract: Procedure for the continuous manufacture of wall elements, characterized in that the different walls are effected continuously on a suitable transport system whereby these walls are assembled in vertical position on this transport system and whereby this procedure consists of at least the following steps; the placing of upper and lower beams (1); the connecting together of the extremities of these upper and lower beams (2) placed behind each other without taking into consideration the length of the walls to be effected with regard to the length of these upper and lower beams; the installation of the windows and doors (3); the placing of the vertical posts (4); the placing of a first covering (5); the installation of electricity wires, sanitary pipes and utility pipes (6); the installation of insulating material (7); the installation of the second covering (8); the sawing out of the coverings at the location of the doors and/or windows (9); the sawing off to measure of the different walls (10).
Patent AU-692429-B2 (AU)
Title: Magnetotherapy apparatus
Inventor: OSTROW ALVIN S
IPC: A61N2/02
Filed: 1993-12-08
Granted: 1998-06-11
Abstract: A magnetotherapy apparatus includes an applicator wrap segmented into a grid of hinged panels. The wrap is adapted to be placed around an injured body member to provide a brace or preform for a conventional cast. Each of the panels further includes a magnetic coil for generating an electromagnetic field directionally oriented perpendicular to a target area. The magnetic fields generated in the adjacent panels are of opposite polarity and cumulatively interact for deeper magnetic flux penetration. An electrostimulation component includes stimulator pads which are selectively energized to provide muscle and/or transcutaneous nerve stimulation for pain sedation. Alternatively, the stimulator pads are used for an electrophoretic pharmaceutical delivery system wherein electrically charged porous pads are in fluid communication with a drug medium.
Patent AU-602866-B2 (AU)
Title: Macroscopically expanded three-dimensional polymeric web for transmitting both dynamically deposited & statically contacted fluids from one surface to the other
Inventor: OUELLETTE WILLIAM ROBERT
IPC: A61F13/15
Filed: 1986-05-30
Granted: 1990-11-01
Abstract: A macroscopically expanded, three-dimensional fluid-handling polymeric web having first and second surfaces located in substantially parallel planes which are remote from one another. The web includes a multiplicity offluid-handling capillary networks of macroscopic cross-section for rapidly transmitting fluids which are dynamically deposited on the first surface of said web to the second surface of said web using the dynamic and gravitational head of the fluid as a primary driving force. Each of the macroscopic cross-section capillary networks originates as an aperture in the first surface of the web and has a continuously interconnected sidewall extending in the direction of the second surface of said web. The continuously interconnected sidewall terminates to form at least one aperture in the second surface of said web, whereby the bulk of the dynamically deposited fluid is transmitted from the first surface to the second surface of said web by the macroscopic cross-section capillary networks. The first surface of the web in which the macroscopic cross-section capillary networks originate further includes a multiplicity of fluid-handling capillary networks which are substantially smaller in cross-section than the macroscopic cross-section fluid-handling capillary networks. The smaller fluid-handling capillary networks exhibit a degree of capillary suction sufficient to transmit static fluid contained on the surface of objectswhich contact the first surface of said web generally in the direction of the second surface of said web by capillary attraction. In a preferred embodiment the smaller fluid handling capillary networks are oppositely oriented from the macroscopic cross-section capillary networks to provide improved visual and tactile impression as well as to enhance the volume of dynamically deposited fluid which flows into the macroscopic cross-section capillary networks.
Patent AU-727474-B2 (AU)
Title: Ascites valve
Inventor: LEVEEN HARRY
IPC: A61M1/00
Filed: 1996-05-24
Granted: 2000-12-14
Abstract: A device for the transfer of body fluids which accumulate in the peritoneum cavity into the vascular system comprising a peritoneal tube connected to the inlet chamber of a hollow plastic implanted valve assembly, causing a valve to open and passing the fluid under pressure into a second chamber from where the fluid is conducted through a venous tubing which is connected to the jugular vein of the patient. The valve assembly comprises a plastic housing with an inlet and outlet, the peritoneal tube being secured to the inlet leading to an inlet reservoir located within the valve housing and the venous tube being secured to the outlet leading from the outlet reservoir located within the valve housing. The valve housing defining a valve seat and having a flexible diaphragm valve which rests against the valve seat and moves away from said valve seat in response to pressure exerted thereon to permit flow of the body fluid from the peritoneum through the valve housing and into the venous tubing which is threaded into a major intrathoracic vein via the internal jugular vein or other alternate access veins.
Patent AU-707862-B2 (AU)
Title: Helper virus-free aav production
Inventor: FERRARI FORREST K
IPC: C12N7/00
Filed: 1996-06-06
Granted: 1999-07-22
Abstract: A method for the production of adeno-associated virus stocks and recombinant adeno-associated virus stocks that are substantially free of contaminating helper virus is described. The method utilizes transfection with helper virus vectors to replace the infection with helper virus used in the conventional method.
Patent AU-595227-B2 (AU)
Title: Electronic surveillance system and transceiver unit therefor
Inventor: CHATWIN IAN MALCOLM
IPC: H04B1/38
Filed: 1986-07-23
Granted: 1990-03-29
Abstract: PCT No. PCT/AU86/00209 Sec. 371 Date Mar. 18, 1987 Sec. 102(e) Date Mar. 18, 1987 PCT Filed Jul. 23, 1986 PCT Pub. No. WO87/00711 PCT Pub. Date Jan. 29, 1987.A transceiver unit for an electronic surveillance system is internally coded with an address-number for identification within the system and is adapted to receive input from sensors detecting alarm conditions. The unit is switchable from an idle condition wherein it transmits digital data relevant to its address-number and status but does not recognize input from a sensor, to a primed condition wherein it transmits digital data relevant to its address-number and status information indicating an alarm condition. The unit is able to receive digital data from other similar units sequentially and display information relevant to the identity and status thereof. In a security system a plurality of such units communicate with each other and in turn transmit the digital data to all the other units of the system simultaneously, either by hard wiring thereto, radio link or other transmission medium. An alarm condition detected by one unit is recognized at all other units of the system. Remote switching of a unit from idle to primed by any of the other units is disclosed.
Patent AU-652126-B2 (AU)
Title: 5-(1-aminocyclohexyl)-2(1H)-pyridinone and related compounds
Inventor: EFFLAND RICHARD CHARLES
IPC: A61P25/04
Filed: 1990-08-16
Granted: 1994-08-18
Abstract: There are described compounds of the formula   <IMAGE>   where n is 1,2 or 3; R1 is hydrogen, formyl, loweralkylcarbonyl, arylloweralkylcarbonyl, loweralkyl, arylloweralkyl,   <IMAGE>   R5 and R6 being independently loweralkyl or alternatively the group <IMAGE>   taken as a whole is   <IMAGE> +TR   <IMAGE>  R2 is hydrogen, loweralkyl, loweralkenyl, arylloweralkyl, -CH2C 3BOND CH, <IMAGE> +TR   <IMAGE>   R7 and R8 being independently loweralkyl or alternatively the group   <IMAGE>   taken as a whole is   <IMAGE>  R3 is hydrogen or loweralkyl; and R4 is hydrogen or loweralkyl; which compounds are useful as analgesic agents and also for treating various memory dysfunctions.
Patent AU-782456-B2 (AU)
Title: Intradermal delivery device including a needle assembly
Inventor: ALCHAS PAUL
IPC: A61M5/158
Filed: 2000-10-09
Granted: 2005-07-28
Abstract: A drug delivery device including a needle assembly (20) facilitates making intradermal injections using a variety of drug container types such as a syringe . A hub (22) supports the needle (24) while a limiter (26) surrounds the needle. The limiter includes a skin engaging surface (42) that is adapted to be received against the skin of an animal to be intradermally injected. A forward end (40) of the needle extends beyond the skin engaging surface a selected distance to limit a depth that the needle penetrates into the animal's skin. <IMAGE>
Patent AU-545185-B2 (AU)
Title: Hybrid cell line
Inventor: KUNG PATRICK CHUNG-SHU
IPC: G01N33/50
Filed: 1981-01-06
Granted: 1985-07-04
Abstract: Hybrid cell line for production of monoclonal antibody to an antigen found on normal human monocytes and granulocytes. The hybrid is formed by fusing splenocytes from immunized BALB/cJ mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
Patent AU-646233-B2 (AU)
Title: Method for producing secretable glycosyltransferases and other golgi processing enzymes
Inventor: PAULSON JAMES C
IPC: C12N15/09
Filed: 1990-10-24
Granted: 1994-02-17
Abstract: A method for genetically engineering cells to produce soluble and secretable Golgi processing enzymes instead of naturally occurring membrane-bound enzymes. Cells are genetically engineered to express glycosyltransferases which lack both a membrane anchor and a retention signal. The resulting altered enzyme becomes soluble and secretable by the cell without losing its catalytic activity. Secretion of the soluble glycosyltransferase by the cell provides for increased production and simplified recovery of glycosyltransferases.
Patent AU-779324-B2 (AU)
Title: Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent
Inventor: MCPHILLIPS ANDREA M
IPC: A61K31/352
Filed: 2000-08-15
Granted: 2005-01-20
Abstract: A formulation of delta-9-tetrahydrocannabinol in a semi-aqueous solvent, such as 35:10:55 alcohol:water:propylene glycol (v/v), produces a stable clear solution near the solubility point of the drug. Because delta-9-tetrahydrocannabinol has poor affinity for the formulation, it is able to partition out and transport across cell membranes to reach the bloodstream quickly. This has been demonstrated by the comparative tmax values achieved in single dose intravenous and 14 day multiple dose inhalation studies conducted in dogs and rats.