baber/WOPTO huggingface dataset:
Patent AT-E421686-T1 (AT)
Inventor: FICKENSCHER KARL DR
IPC: G01N33/48
Filed: 1999-11-12
Granted: 2009-02-15
Abstract: A multi-cuvette rotor (I) for an automatic biological fluid analyzer, is new and has measuring cuvettes of different design as well as chambers of different geometries arranged in a same or different implementation, which receive different volumes of fluid. The parts of (I) are attached together and are able to produce measurements.
Patent AT-E367666-T1 (AT)
Inventor: PAVLOVIC SLOBODAN
IPC: H01R13/719
Filed: 1999-11-25
Granted: 2007-08-15
Abstract: An electrical filter connector assembly comprises first electrical terminals (18) having female contact areas (38), two ferrite hoods (20) provided as two separate members and separately mounted on respective ones of the first terminals over the female contact areas (38) and second electrical terminals having male contact areas (48) located in the female contact areas (38) of the first terminals, at least one of said ferrite hoods being made of electrically conductive material. <IMAGE>
Patent AT-E208355-T1 (AT)
Inventor: SCHLEGEL SIGURD
IPC: B01D21/00
Filed: 1999-02-15
Granted: 2001-11-15
Abstract: The invention relates to a round settling tank (1) for separating sludge from waste water. This type of tank comprises an inlet (2) to allow the waste water to flow into the settling tank (1), a clearing device for the settled sludge which scrapes along the base (7) of the settling tank (1), as well as a withdrawing device (8) for the sludge and an outlet (10) for the clear water. According to the invention these settling tanks operate with turbulence in the separating area and a stilled water flow in other areas. The waste-water inlet (2) discharges at the height of the thickening and evacuating layer (11) such that the settling capacity is raised considerably.
Patent AT-E217922-T1 (AT)
Inventor: DE GIOVANNI GIUSEPPE
IPC: D06G3/04
Filed: 1999-04-20
Granted: 2002-06-15
Abstract: A device has been realized for turning tubular textile products inside out, in which a tubular body (22), designed for the purpose, is moved between an idle position and a working position for executing this operation. Active means of suction on the tubular body (22) create a flow of air inside said body when it is in its operative position, and pick-up means (21), placed at the operative position of the tubular body (22), hold the textile product (3) and fit it externally onto the tubular body. Once the product (3) has been fitted onto the tubular body (22), this latter moves from the working position towards the idle position gradually drawing on the textile product and thus completely automating the reversing process.
Patent AT-E231748-T1 (AT)
Inventor: LEMOINE ALAIN
IPC: B05D3/12
Filed: 1999-03-17
Granted: 2003-02-15
Abstract: Powders or granules are deposited on a film (10) or on a band (100) by means of several rollers (1,2,3,4) which are driven at a constant speed by a conveyor (5). There are several vacuum tables (20,21,22) which are given an alternate oscillatory movement of low amplitude. The support is tensioned in its movement direction.
Patent AT-E253045-T1 (AT)
Inventor: ROMERO ARTHUR GLENN
IPC: A61P25/00
Filed: 1999-05-07
Granted: 2003-11-15
Abstract: Compounds of Formula I and their pharmaceutically acceptable salts having selective dopamine D3 receptor activity suitable for treating central nervous system disorders. Formula I: R1 is independently H or a C1-C8 alkyl including isomeric forms thereof; R2 is H, C1-C3 alkyl, a halogen, OCH3 , OCF3, CF3, CN, SCH3 or NHCOCH3; and R3 is H, C1-C3 alkyl, a halogen, OCH3 , OCF3, CF3, CN, SCH3 or NHCOCH3.
Patent AT-E264466-T1 (AT)
Inventor: DUPOIRON FRANCOIS
IPC: F16L11/08
Filed: 1999-07-30
Granted: 2004-04-15
Abstract: A flexible tubular pipe having an internal sheath and a pressure vault around the sheath with a helically would short pitch metal wire. The metal wire has an I-shaped cross-section with a narrowed central web and greater thickness internal and external flanges. Recesses in at least one set of the flanges enable fastening elements to be installed for holding to adjacent wire windings. The ratios of widths of the flanges, height and width of the wire, moments of inertia in the width wise and radial direction are disclosed.
Patent AT-E261340-T1 (AT)
Inventor: NIEMAN JAN
IPC: B01J29/16
Filed: 1999-07-15
Granted: 2004-03-15
Abstract: The invention pertains to a carrier composition comprising (a) at least 30 wt % of a synthetic cracking component, based on the total weight of the carrier composition, which comprises oxidic compounds of one or more trivalent metallic elements, tetravalent metallic elements, and divalent metallic elements, said cracking component comprising elemental clay platelets with an average diameter of 1 mum or less and an average degree of stacking of 20 platelets per stack or less, and/or comprising a cogel with a saponite content CA of less than 60 %, in which the total of sodium and potassium amounts to less than 1 wt %, based on the total weight of the cogel, and (b) 1 -25 wt % of a zeolite Y, based on the total weight of the carrier composition, with a unit cell size below 24.35 å. The invention further pertains to a catalyst comprising said carrier composition and at least a hydrogenation metal, and a process for converting heavy feedstock into middle distillates using said catalyst.
Patent AT-E232430-T1 (AT)
Inventor: DUNN JOSEPH A
IPC: B21D26/02
Filed: 1999-09-02
Granted: 2003-02-15
Abstract: A process of mechanical hydroforming, in which a hollow tube is caused to expand against the interior surface of a die that surrounds the tube by hydraulic pressure applied to a liquid that fills the interior of the tube, is improved by coating the part of the exterior surface of the tube that comes into contact with the die surface against which it expands with a wax that is solid at normal room temperature but can be maintained fully melted and in contact with air, without showing any visible evidence of decomposition, at a temperature that is at least 75 degrees C. Preferably, the wax is applied to the surface to be hydroformed by spraying from melt onto the surface while the latter is maintained above the melt temperature of the wax. Shortly after the wax has been thus applied to the surface, the wax is cooled until it solidifies. Most preferably, the wax is an "oxidized hydrocarbon" wax that is about 95% hydrocarbon and 5% straight chain carboxylic acids and contains a wide variety of molecular weights of both hydrocarbons and carboxylic acids.
Patent AT-E320138-T1 (AT)
Inventor: MARTINIERE JEAN-PIERRE
IPC: H04N7/173
Filed: 1999-12-17
Granted: 2006-03-15
Abstract: The invention concerns a device assembling the utilities and the uplink/return channels of a mobile telephone device (DES), and the display and downlink channel of a receiver terminal (TRi) served by a diffusion network (RDi) in an equipment interacting with data servers (SD1-SDj) capable of being queried by the device and displaying their pages in the terminal designated among or together with others from the device (DES). The device (DES) calls a management server (SG) so that a reception server (SAi) diffuses an identifier of the terminal and of the data of a data server (SDj) with an identifier so as to be recognised by the receiver terminal. The data server (SDj), designated in a broadcast list, displayed in the terminal, is called by the management server (SG). Through the management server (SG) communications are set up between the device (DES), data server (SDj) and the terminal (TRi).
Patent AT-E349908-T1 (AT)
Inventor: BAVONE JOSEPH M
IPC: A23C19/09
Filed: 1999-11-29
Granted: 2007-01-15
Abstract: Certain coating formulations provide an adhesive effect that enhances points of contact between the individual pieces of food to be joined in deep-fried unified food servings. Batter mixes for restaurant food coating compositions in accordance with the present invention contain 35%-75% adhesion component, 2%-11% viscosity component, and 5%-50% crispness component. Batter mixes for processor food coating compositions in accordance with the present invention contain 30%-70% adhesion component, 10%-25% film-forming component, 3%-9% viscosity component, and 8%-40% crispness component. Both compositions may additionally contain 0.1%-2% leavening component, 0.1%-15% flavoring component, 0.1%-1% coloring component, and/or 0.1%-1% processing aid. Also provided are unified food serving products that are characterized by a persistent crispy, crunchy texture and produced by a process that includes: providing multiple pieces of a food to be cooked; applying a "back of the house" food coating composition to each piece of food while in a mold; immersing the mold in a heated deep-frying medium to cook the food and join the pieces into a unified food serving reflecting the shape of the mold; and removing the unified food serving product from the deep-frying medium and the mold. Another process provides unified food serving products, characterized by a persistent crispy, crunchy texture, produced by the process of providing multiple pieces of a food to be cooked; applying a "processor" food coating composition to each piece of food; individually freezing each piece of food; adding the frozen pieces of food to a mold; immersing the coated pieces of food in a mold in a heated deep-frying medium to cook the food and join the pieces into a unified food serving reflecting the shape of the mold; and removing the unified food serving product from the deep-frying medium and the mold.
Patent AT-E256958-T1 (AT)
Inventor: RUNG MARTIN
IPC: H04R1/40
Filed: 1999-11-12
Granted: 2004-01-15
Abstract: Microphone array which comprises a multiple of microphones which are arranged in an elongated element or housing, in which the individual microphones in the microphone array are arranged in pairs. The individual microphones in each pair are disposed on each their side of a centerline for the microphone array, where the signals from the microphones are summated in the formation of the output signal from the microphone array. The microphones on each side of the centerline of the microphone array are disposed with non-equidistant spacing between them, and low-pass filters are coupled between each microphone and a summation link, in that the microphones associated with one and the same pair are connected to low-pass filters having the same cut-off frequency. The cut-off frequency for the low-pass filters is different for each pair of microphones, in that the cut-off frequency is lowest for that pair of microphones which lie furthest away from the centerline, and is higher the closer the pair of microphones lies to the centerline. The microphone array is arranged in such a manner that the distances between the microphones and the cut-off frequencies for the low-pass filters are mutually adjusted in relation to one another.
Patent DE-00915597-T1 (DE)
Inventor: LOTVEIT BARD
IPC: B60C27/18
Filed: 2000-04-06
Abstract: A device to be fitted on a vehicle wheel (1) of a predetermined size, comprises a belt (3) intended to encircle the tread (4) of (1). The internal circumference of (3) is at least 4% larger than the largest circumference of (1) due to which the device remains intact on (1). The device to be fitted on (1) of a predetermined size comprises (3) intended to encircle (4) of (1) and is held in place by flexible inner and outer side portions (5,8). The inner side of the wheel is tightened by an elastic member (7). The internal circumference of (3) is at least 4% larger than the largest circumference of (1). An independent claim is also included for a method for fitting the device. The wheel is rotated by means of the vehicle and the remaining part of the inner side portion is moved to a position where it is permitted to assume its place on inside of (1) and pull (3) in place along (4) of (1).
Patent DE-08017758-T1 (DE)
Inventor: HOPKINS LAWRENCE
IPC: F04D25/16
Filed: 2004-03-19
Abstract: A fan array fan section in an air-handling system comprising a plurality of fan units (200) arranged in a fan array and positioned within an air-handling compartment (202). One preferred embodiment may include an array controller (300) programmed to operate the plurality of fan units (200) at substantially peak efficiency. The plurality of fan units (200) may be arranged in a true array configuration, a spaced pattern array configuration, a checker board array configuration, rows slightly offset array configuration, columns slightly offset array configuration, or a staggered array configuration.
Patent DE-309005-T1 (DE)
IPC: A21C3/02
Filed: 1988-01-26
Abstract: System for forming a laminate consisting of dough and fat, comprising in a single reducing station (1 min , 1 sec ) first (12, 16; 29, 31) and second (13, 17; 29, 33) reducing means which are each suitable for receiving a first (8) and second (10) ingoing layer consisting of dough and fat and for delivering a first (9) and second (11) outgoing layer, less thick than the respective ingoing layers, a laminating station (2 min ) which is suitable for receiving the first outgoing layer (9), and for partially placing on each other of parts of the first outgoing layer (9) for forming and delivering the second outgoing layer (10), with a displacement direction opposite to the first outgoing layer (9), and comprising first to fourth conveyor means (4 to 7), having essentially parallel running conveyance directions for conveying the layers (8 to 11) thereon.
Patent DE-1094759-T1 (DE)
Inventor: MANGIONE PAOLO
IPC: A61B17/70
Filed: 1999-04-27
Abstract: A backbone osteosynthesis system for anterior fixing comprising first and second arms, each capable of receiving bone screws and a longitudinal plate for rigidly linking the arms, the plate being in one single piece with the first arm. The system comprises a way to adjust the second arm in a longitudinal position on the plate.
Patent ES-2173826-T1 (ES)
Title: Dispositivo y metodo para determinar cortocircuitos raros.
Inventor: OHTA MANABU
IPC: B60R16/023
Filed: 2001-08-30
Abstract: Un dispositivo de determinación de cortocircuitos raros para determinar si ha tenido lugar en un circuito de carga un cortocircuito raro que resulta de la generación de calor que excede un valor predeterminado, incluyendo el dispositivo de determinación de cortocircuitos raros un sensor (2) para detectar una corriente de carga que uye a través del circuito de carga y para generar una señal de detección, y un circuito de determinación (6) conectado al sensor para determinar si ha tenido lugar una cortocircuito raro, estando caracterizado el dispositivo de determinación de cortocircuitos raros porque: el circuito de determinación calcula uno de un primer parámetro y un segundo parámetro cada intervalo de tiempo predeterminado basándose en la señal de detección, reriéndose el primer parámetro a un primer período de tiempo durante el cual la corriente de carga excede un valor de corriente de referencia predeterminado, y reriéndose el segundo parámetro a un segundo período de tiempo durante el cual la corriente de carga es menor o igual que el valor de corriente de referencia predeterminado, en donde el circuito de determinación acumula el calculado de los parámetros cada intervalo de tiempo predeterminado para calcular un valor de parámetro acumulativo y determina si ha tenido lugar un cortocircuito raro basándose en el valor de parámetro acumulativo.
Patent ES-2209673-T1 (ES)
Inventor: ZEIRA ELDAD
IPC: H04B1/69
Filed: 2001-04-30
Abstract: The present invention is a method and system for controlling downlink transmission power levels in a spread spectrum time division communications system having frames with time slots for communication, which receives at a user equipment(UE) a downlink communication from a base station and determines an error rate of the received communication. The UE then produces power level adjustments for each of the time slots based in part on the error rate and transmits an uplink communication to the base station which includes the power level. In response to the power level adjustments and (or) other information, transmission power level is set for each time slot in the downlink communication.
Patent ES-2033629-T1 (ES)
Title: Conector de paneles.
IPC: E04B2/74
Filed: 1991-04-19
Abstract: UN CONECTOR PARA UN PANEL DE SEPARACION DE UNA OFICINA QUE TIENE UN MARCO DEL PANEL RECTANGULAR EN LOS BORDES DEL MISMO Y UN CANAL DE CONDUCCION METALICO (56) FORMADO EN UNA PARTE SUPERIOR DEL PANEL. EL CONECTOR CONECTA DE MANERA RIGIDA LOS MARCOS DEL PANEL RECTANGULARES A LOS BORDES LATERALES E INCLUYE BLOQUES CUNEIFORMES SUPERIORES E INFERIORES (70, 130) SOBRE LOS BORDES DEL PANEL Y BLOQUES DE ACOPLAMIENTO (110, 120) ADAPTADOS PARA SUJETAR LOS BLOQUES CUNEIFORMES Y ACOPLAR LOS BLOQUES CUNEIFORMES DE MARCOS ADYECENTES ENTRE SI. UN TUBO DE ACOPLAMIENTO (96) CONECTA LOS BLOQUES DE ACOPLAMIENTO. EN LA PARTE SUPERIOR DE LOS BLOQUES CUNEIFORMES SE HA FORMADO UN CANAL DE CONDUCCION METALICO (56) Y AL MENOS UN BLOQUE CUNEIFORME TIENE UNA CONFIGURACION EN U CON UNA SUPERFICIE CUNEIFORME FORMADA EN UN RECODO DE LA U, LAS PIERNAS DEL BLOQUE CUNEIFORME SE EXTIENDEN HACIA ARRIBA A LO LARGO DE LOS LADOS SUPERIORES DEL PANEL Y EN REGISTRO CON EL CANAL DE CONDUCCION METALICO. SE PUEDE MONTAR UN CONECTORDE CAMBIO DE ALTURA (180), QUE TIENE UN ADAPTADOR DEL BLOQUE CUNEIFORME EXTRAIBLE, AL LADO DEL MARCO DEL PANEL PARA CAMBIAR LA ALTURA SIN UTILIZAR UN SEPARADOR O ESQUINA. UN TUBO DE ACOPLAMIENTO PUEDE FORMAR UN SEPARADOR O ESQUINA ENTRE PANELES ADYACENTES. EL TUBO DE ACOPLAMIENTO ES RECTANGULAR EN LA CONFIGURACION DE LA SECCION TRANSVERSAL Y PUEDE TENER REVESTIMIENTOS COMETICOS ACOPLADOS AL MISMO. SE PUEDE MONTAR TAMBIEN UNA EXTRUSION DE RELLENO (150) EN LAS PARTES LATERALES DEL TUBO DE ACOPLAMIENTO ENTRE LOS BLOQUES CUNEIFORMES SUPERIOR E INFERIOR PARA RELLENAR EL ESPACIO ENTRE ELLOS. UN CONECTOR DE BASE CONSTA DE UNA PLACA BASE, UNA CUBIERTA BASE Y UN POSTE. LA PLACA BASE ESTA MONTADA EN LA PARTE INFERIOR DEL TUBO DE ACOPLAMIENTO, EL POSTE ESTA MONTADO EN LA PLACA BASE Y SE EXTIENDE HACIA ABAJO DEL MISMO Y LA CUBIERTA BASE ESTA MONTADA A LA PLACA BASE Y AL POSTE Y SE EXTIENDE HACIA ABAJO DESDE UNA PARTE INFERIOR DEL TUBO DE ACOPLAMIENTO.
Patent ES-2104519-T1 (ES)
Title: Maquina de separacion de fallos utilizando fisica cualitativa.
Inventor: CLARK ROBERT T
IPC: G06F11/22
Filed: 1995-04-04
Abstract: LA PRESENCIA DE ERRORES PARTICULARES EN UNA MAQUINA SE DETERMINA (58) POR LA UTILIZACION DE SUSPENSION RESTRINGIDA Y UN MODELO DE FISICA CUALITATIVA DE LA MAQUINA. LAS SEÑALES DE LA MAQUINA RECIBIDAS PUEDEN SER PROPAGADAS (69) A TRAVES DEL MODELO Y LOS IMPLICANTES DE LOS VALORES ASIGNADOS A LAS VARIABLES PUEDEN DETERMINARSE Y OTRAS VARIABLES PUEDEN RESTRINGIRSE (187) SEGUN LA UNION DE LOS IMPLICANTES. EL USUARIO PUEDE OBSERVAR UNAS INDICACIONES SOBRE LA EJECUCION DEL PROCESO EN LA PANTALLA (72) DE PRUEBA DE LA MAQUINA QUE PROVOCA UN CAMBIO EN LA CONFIGURACION DE LA MAQUINA. EL TIEMPO DE LA EJECUCION DE LA PRUEBA PUEDE SER UN FACTOR PARA EL USUARIO EN LA ELECCION DE LA PRUEBA OPTIMA QUE SE VA A LLEVAR A CABO. EL MODELO DE FISICA CUALITATIVA (310) DE LA MAQUINA PUEDE SER CONSTRUIDO UTILIZANDO UNA INTERFAZ DE USUARIO GRAFICA (302) QUE PERMITE LA SELECCION Y LA INTERCONEXION DE LOS COMPONENTES DE LA MAQUINA (306) PARA EL MODELO DE TAL FORMA QUE EL USUARIO PUEDE DEFINIR UN DOMINIO DE REFERENCIAPARA PROPORCIONAR LAS DEFINICIONES DE LOS ESPACIOS DE VALOR CUALITATIVO DE LAS VARIABLES DEL MODELO. SE PUEDEN UTILIZAR TAMBIEN PLANTILLAS DE PRUEBA GENERICAS EN EL DESARROLLO DEL MODELO.
Patent ES-2106702-T1 (ES)
Title: Producto para el teñido oxidativo del cabello.
Inventor: BALZER WOLFGANG R DR
IPC: A61Q5/10
Filed: 1996-10-09
Abstract: LA INVENCION TRATA DE UN COMPUESTO QUE TIÑE DE FORMA OXIDATIVA LOS CABELLOS, QUE CONTIENE COMO SUSTANCIA ACTIVA UNA MEZCLA COMPUESTA DE 2-(2,5-DIAMINOFENIL)ETANOL Y 4-AMINO-2-AMINOMETILFENOL.
Patent ES-2118675-T1 (ES)
Title: Tapa de cierre roscada para recipientes.
Inventor: BREUER HANS-WERNER
IPC: B65D41/04
Filed: 1996-05-10
Abstract: SE PROPONE UNA TAPA (1) ROSCADA FABRICADA DE PLASTICO, TENIENDO LA TAPA EN SU SUPERFICIE INTERIOR DE LA PARTE SUPERIOR (4) DE LA TAPA UN LABIO (8) DE CIERRE CIRCULAR DE UNA RESISTENCIA A LA FLEXION DADA QUE, CUANDO LA TAPA ESTA ROSCADO, CIERRA HERMETICAMENTE LA BOCA (2) DEL RECIPIENTE DE SU SUPERFICIE CILINDRICA (2'') INTERNA DE LA BOCA. SITUADO A UNA DETERMINADA DISTANCIA RADIAL HACIA EL INTERIOR DEL LABIO DE CIERRE SE ENCUENTRA UN NERVIO (8) CIRCULAR QUE SE EXTIENDE HACIA ABAJO CON UNA SECCION AHUSADA DESDE LA SUPERFICIE INTERIOR DE LA PARTE SUPERIOR DE LA TAPA, PERO QUE NO SE EXTIENDE TANTO HACIA ABAJO COMO EL LABIO SELLANTE, DE FORMA QUE, CUANDO LA TAPA SE ENROSCA, EL NERVIO HACE CONTACTO CON EL LABIO DE CIERRE Y LO PRESIONA CONTRA LA SUPERFICIE INTERNA DE LA BOCA DEL RECIPIENTE.
Patent CY-1110035-T1 (CY)
Inventor: LACROIX OLIVIER
IPC: B65G39/14
Filed: 2006-08-28
Abstract: The retention device includes a tilting support on which a conveyance roller (7) is mounted. The support consists of two cheek-plates (13A), and two slots to accommodate an axle of the roller.
Patent CY-1108859-T1 (CY)
Title: Παραγωγα κιναζολινης και πυριδοπυριμιδινης
Inventor: CARTER MALCOME CLIVE
IPC: C07D405/04
Filed: 2009-03-06
Abstract: Αποκαλύπτονται χημικές ενώσεις με χημικούς τύπους (IV) και (VIII) καθώς και μέθοδοι για την παρασκευή τους:
Patent CY-1113603-T1 (CY)
Title: Εντομοκτονο βαμβακι cot102ones
Inventor: ELLIS DANIEL MURRAY
IPC: C12Q1/6888
Filed: 2012-09-04
Abstract: Η παρούσα αίτηση αναφέρεται σε διαγονιδιακό φυτό βαμβακιού, ανθεκτικό σε έντομα. Ειδικότερα, αναφέρεται σε ένα συγκεκριμένο συμβάν, προσδιοριζόμενο ως COT102. Η αίτηση επίσης αναφέρεται σε πολυνουκλεοτίδια, τα οποία είναι χαρακτηριστικά του COT102 συμβάντος, σε φυτά που περιλαμβάνουν τα εν λόγω πολυνουκλεοτίδια και σε μεθόδους ανίχνευσης του COT102 συμβάντος. To COT102 συμβάν παρουσιάζει ένα νέο γενότυπο που περιλαμβάνει δύο κασέτες έκφρασης. Η πρώτη κασέτα περιλαμβάνει έναν κατάλληλο υποκινητή για έκφραση σε φυτά λειτουργικά συνδεδεμένα με ένα γονίδιο που κωδικοποιεί μία VIP3A εντομοκτόνο τοξίνη, χρήσιμη στον έλεγχο ενός ευρέος φάσματος ζιζανίων λεπιδοπτέρων εντόμων και ένα κατάλληλο σήμα πολυαδενυλίωσης. Η δεύτερη κασέτα περιλαμβάνει ένα γονίδιο το οποίο, όταν εκφράζεται, μπορεί να χρησιμοποιηθεί ως επιλέξιμος ιχνηθέτης.
Patent CY-1123785-T1 (CY)
Title: Μια διεργασια για την παρασκευη μιας εκ του στοματος χορηγουμενης μορφης δοσολογιας πολλαπλων μοναδων τροποποιημενης αποδεσμευσης της ηλεκτρικης δοξυλαμινης και υδροχλωρικης πυριδοξινης
Inventor: SAURA I VALLS MARC
IPC: A61K9/48
Filed: 2021-01-27
Abstract: Η παρούσα εφεύρεση σχετίζεται με μια διεργασία για την παρασκευή μιας εκ του στόματος χορηγούμενης μορφής δοσολογίας πολλαπλών μονάδων τροποποιημένης αποδέσμευσης περιλαμβάνοντας μια πλειάδα σβόλων τροποποιημένης αποδέσμευσης της δοξυλαμίνης ή άλατος εξ αυτής και σβόλων τροποποιημένης αποδέσμευσης της πυριδοξίνης ή ενός άλατος εξ αυτής• όπου η διεργασία περιλαμβάνει επικάλυψη των σβόλων της δοξυλαμίνης έχοντας την εσώτερη ενεργή στοιβάδα επικάλυψης και την ενδιάμεση εντερική στοιβάδα επικάλυψης• και των σβόλων πυριδοξίνης έχοντας την εσώτερη ενεργή στοιβάδα επικάλυψης, όπου το βήμα επικάλυψης περιλαμβάνοντας ταυτόχρονο ψεκασμό ενός μείγματος που περιλαμβάνει τους παράγοντες επικάλυψης εντερικής και τροποποιημένης αποδέσμευσης και παράγοντες σχηματισμού-πόρων προσθήκης σε μορφή κόνεων.
Patent CY-1124917-T1 (CY)
Title: Παρασκευη στερεων συμπλοκων κυκλοδεξtρινης για παραδοση οφθαλμικου δραστικου φαρμακευτικου συστατικου
Inventor: LOFTSSON THORSTEINN
IPC: A61K47/69
Filed: 2022-01-25
Abstract: Η παρούσα δημοσιοποίηση σχετίζεται με οφθαλμικές συνθέσεις που περιέχουν στερεά σύμπλοκα δραστικού φαρμακευτικού συστατικού και κυκλοδεξτρίνης, με τη μέθοδο παρασκευής τους και τις χρήσεις τους. Οι συνθέσεις μπορεί να περιλαμβάνουν ένα σύμπλοκο δραστικού παράγοντα φαρμάκου/κυκλοδεξτρίνης ουσιαστικά διαλυμένο σε ένα υδατικό όχημα οφθαλμικών σταγόνων. Η οφθαλμική σύνθεση έχει γενικά τη μορφή ενός μικροεναιωρήματος που περιλαμβάνει ένα σύμπλοκο δραστικού παράγοντα που έχει μια διάμετρο μικρότερη από περίπου 100 μm.