baber/WOPTO huggingface dataset:
Patent CY-1114831-T1 (CY)
Title: Πολυγωνικος καδος για υγροποιημενο φυσικο αεριο
Inventor: EZZARHOUNI ADNAN
IPC: F17C3/02
Filed: 2013-10-02
Abstract: Κάδος (1) στεγανός και/ή θερμικά μονωμένος, περιλαμβάνοντας μια φέρουσα κατασκευή (4), έναν στεγανοποιητικό φραγμό και/ή έναν θερμικά μονωτικό φραγμό, παρουσιάζοντας ο εν λόγω στεγανοποιητικός φραγμός και/ή ο εν λόγω θερμικά μονωτικός φραγμός κυλινδρικό σχήμα και περιλαμβάνοντας ένα κατακόρυφο τοίχωμα (2) κι'ένα τοίχωμα πυθμένα (3) όπου το εν λόγω κατακόρυφο τοίχωμα παρουσιάζει μια πληθώρα κατακόρυφων φύλλων (8, 8'), περιβάλλοντας η εν λόγω φέρουσα κατασκευή το εν λόγω κατακόρυφο τοίχωμα, και όπου το εν λόγω τοίχωμα πυθμένα εμπεριέχει μια πληθώρα ορθογωνικών στοιχείων (5), κατανεμημένων σε τομείς, είδωλα εκ περιστροφής οι μεν των δε, με τις ακμές των ορθογωνικών στοιχείων ενός εκ των εν λόγω τομέων να είναι αντίστοιχα παράλληλες και κάθετες στο ένα εκ των εν λόγω κατακόρυφων φύλλων (8), χαρακτηριζόμενος από το ότι ο αριθμός των εν λόγω κατακόρυφων φύλλων είναι το διπλάσιο του αριθμού των εν λόγω τομέων.
Patent CY-1116041-T1 (CY)
Title: Μεσα και μεθοδοι για τη θεραπευτικη αγωγη νεοπλασματικων νοσων
Inventor: BAEUERLE PATRICK
IPC: C07K16/46
Filed: 2015-02-25
Abstract: Εδώ παρέχονται φαρμακευτικά μέσα και μέθοδοι για την πρόληψη, θεραπευτική αγωγή ή βελτίωση ανώδυνου ή επιθετικού λεμφώματος Β-κυττάρων τύπου μη Hodgkin (Β NHL) και Β-κυτταρικής λευχαιμίας που περιλαμβάνουν τη χορήγηση μιας κατασκευής αμφιειδικού αντισώματος μονής αλυσίδας σε ένα υποκείμενο που χρήζει αυτής και τη χρησιμοποίηση της ρηθείσας κατασκευής αμφιειδικού αντισώματος μονής αλυσίδας για την παρασκευή μιας φαρμακευτικής σύνθεσης για την πρόληψη, θεραπευτική αγωγή ή βελτίωση ανώδυνου ή επιθετικού λεμφώματος Β-κυττάρων τύπου μη Hodgkin (Β NHL) και Β-κυτταρικής λευχαιμίας, διά της οποίας η ρηθείσα κατασκευή πρόκειται να χορηγηθεί επί τουλάχιστον 1 εβδομάδα σε καθορισμένες ημερήσιες δόσεις. Επιπλέον, η εφεύρεση αναφέρεται σε κιτία που περιλαμβάνουν μια κατασκευή αμφιειδικού αντισώματος μονής αλυσίδας που πρόκειται να χρησιμοποιηθεί σύμφωνα με την παρούσα εφεύρεση.
Patent CY-1116253-T1 (CY)
Title: Νεα μεθοδος συνθεσης του (2ε)-3-(3,4-διμεθοξυφαινυλ)προπ-2-ενονιτριλιου και εφαρμογη στη συνθεση της ιβαβραδινης και των αλατων προσθηκης αυτης με ενα φαρμακευτικως αποδεκτο οξυ
Inventor: CARRANZA MARIA DEL PILAR
IPC: C07C253/30
Filed: 2015-05-07
Abstract: Μέθοδος σύνθεσης της ένωσης του τύπου (I): Εφαρμογή στη σύνθεση της ιβαβραδίνης και των αλάτων προσθήκης αυτής με ένα φαρμακευτικώς αποδεκτό οξύ και των ένυδρων αλάτων της.
Patent CY-1117203-T1 (CY)
Title: Διαλυτα «βαριας αλυσιδας-mono» αντισωματα
Inventor: GROSVELD FRANKLIN GERARDUS
IPC: C07K16/12
Filed: 2016-02-17
Abstract: Η παρούσα εφεύρεση παρέχει ένα υψηλής συγγένειας, αντιγονοειδικό, διαλυτό βαριάς αλυσίδας-μόνο αντίσωμα το οποίον δεν έχει χαρακτηριστικά αμινοξικών υποκαταστάσεων που σχετίζονται με καμηλοειδή και έχει FR2 υποκαταστάσεις που δεν ανιχνεύονται σε αντισώματα τα οποία περιλαμβάνουν βαριά και ελαφριά αλυσίδα• δείχνει αυξημένη καθαρή υδροφοβικότητα μέσα στην CDR1 και έναν αυξημένο αριθμό φορτισμένων αμινοξέων που υπάρχουν σε CDR3• και περιλαμβάνει μία ή περισσότερες αμινοξικές υποκαταστάσεις μέσα στο πλαίσιο β-πτυχωτού ελάσματος οδηγώντας σε αυξημένη καθαρή υδροφοβικότητα μέσα στο FR1 και έναν αυξημένο αριθμό φορτισμένων αμινοξέων που υπάρχουν σε FR3. Επίσης παρέχονται VH πεδία που έχουν τις ίδιες ιδιότητες, γονιδιακά τμήματα για την παραγωγή τους, μέθοδοι για την παραγωγή τους, διαγονιδιακά ζώα και χρήσεις των VH πεδίων του αντισώματος σε θεραπεία.
Patent CY-1119507-T1 (CY)
Title: Μεθοδος για την παραγωγη ηλεκτρικης ενεργειας, καθως και χρηση ενος εργαζομενου μεσου
Inventor: BOZEK EWA
IPC: F01K25/10
Filed: 2017-10-17
Abstract: Η εφεύρεση αφορά μια μέθοδο για την παραγωγή ηλεκτρικής ενέργειας με τη βοήθεια τουλάχιστον μίας πηγής θερμότητας χαμηλής θερμοκρασίας (2), όπου πραγματοποιείται μια κυκλική διεργασία VPT (1, 10, 100). Για την αύξηση του βαθμού απόδοσης της κυκλικής διεργασίας VPT προτείνεται η χρήση ορισμένων εργαζόμενων μέσων.
Patent CY-1119782-T1 (CY)
Title: Συζευγματα πυρρολοβενζοδιαζεπινης-αντισωματος αντι-cd22
Inventor: VAN BERKEL PATRICIUS HENDRIKUS CORNELIS
IPC: C07K16/30
Filed: 2017-12-18
Abstract: Συζεύγματα απομονωμένου εξανθρωπισμένου αντισώματος αντι-CD22 με διμερή PBD.
Patent CY-1120800-T1 (CY)
Title: Μεθοδοι και συνθεσεις για την in vivo ενεργοποιηση του σχηματισμου παγκρεατικων βητα κυτταρων
Inventor: DOIRON BRUNO
IPC: C12N15/67
Filed: 2018-07-18
Abstract: Οι υλοποιήσεις της εφεύρεσης διεγείρουν τρία επίπεδα φυσιολογίας των βήτα κυττάρων: (i) μεταβολισμό γλυκόζης, (ii) λειτουργία υποδοχέα μεμβράνης, και (iii) παράγοντες μεταγραφής που οδηγούν στον in vivo σχηματισμό βήτα κυττάρων στο πάγκρεας με σκοπό τη θεραπευτική αντιμετώπιση του διαβήτη. Σε ορισμένες όψεις, οι μέθοδοι περιλαμβάνουν την ενσωμάτωση τριών επιπέδων κυτταρικής φυσιολογίας: μεταβολισμό, λειτουργία υποδοχέα μεμβράνης και γονιδιακή μεταγραφή. Η ενσωμάτωση πολλαπλών επιπέδων κυτταρικής φυσιολογίας παράγει μια συνεργιστική επίδραση στον σχηματισμό βήτα κυττάρων.
Patent GR-940300052-T1 (GR)
Title: Protein having cytokin type activity, recombinant DNA coding for this protein, transformed cells and microorganisms.
Inventor: CAPUT DANIEL
IPC: C12R1/865
Filed: 1994-08-31
Abstract: The present invention relates to a protein possessing a cytokine type activity, or a precursor of this protein, which comprises the following amino acid sequence (a1): <IMAGE> in which Xaa represents Asp or Gly.o
Patent HR-P20110111-T1 (HR)
Title: New hybrid system for brassica napus
Inventor: STIEWE GUNTHER
IPC: A01H5/10
Filed: 2011-02-15
Abstract: SUMMARY OF THE INVENTION   This invention relates to a nuclear conditional male sterility system in Brassica napus. Embodiments of the invention provide for the (male sterile) prebasic female (MsMsrfrf), the (male fertile) maintainer line (msmsrfrf), the (male sterile) basic female line (Msmsrfrf), and hybrid lines. Further provided are methods for the production of those lines. Further embodiments of the invention relate to markers associated to the sterility, fertility and maintainer alleles and the use of those markers in providing a hybrid system.
Patent SI-1785370-T1 (SI)
Title: Insulated cup
Inventor: D AMATO GIANFRANCO
IPC: B65D21/02
Filed: 2005-11-11
Abstract: Cup (1) with an internal wall (2) and an external sleeve (5), the sleeve being formed from a blank (10) of corrugated material comprising a corrugated layer (6) and a substrate Iayer (7) and being arranged such that the substrate layer (7) faces towards the internal wall of the cup. A first end (12) of the blank (10) is overlapped at least partially by a second end (14) of the blank in an overlapping area (19). Further, the sleeve (5) is adhesively attached to the internal wall of the cup (1) at least by a first area (15) of adhesive being provided on an inner side of the sleeve on the first end of the blank and by a second area (17) of adhesive being provided on an inner side of the sleeve on the second end of the blank. The second area (17) of adhesive is provided at a distance from the overlapping edge (13) of the blank, thereby attaching each end of the blank (10) separately to the internal wall of the cup (1).
Patent SI-1735278-T1 (SI)
Title: Histamine h3 receptor agents, preparation and therapeutic uses
Inventor: BEAVERS LISA SELSAM
IPC: C07D405/10
Filed: 2005-03-25
Abstract: The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof, which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases.
Patent SI-2135836-T1 (SI)
Title: Two-part telescopic arm of a crane
Inventor: STEINDL HANNES
IPC: B66C23/00
Filed: 2006-04-03
Abstract: The arm has crane extendable two-piece telescope arm with a crane-lateral exterior partial arm (3) and an end sided internal partial arm (4). The crane arm has piping, which leads to connections within the end area of the buckling arm. The connections are covered partly by a cover (21) detachably arranged at the end area of the buckling arm (1). The distance of the connections of the hose lines (5) is accessible. An independent claim is also included for a telescope arm with the cover with a u-shaped cross section.
Patent SI-1838933-T1 (SI)
Title: Giessvorrichtung und Verfahren zur Herstellung von stapelbaren ineinandergreifenden Ziegeln mit einer glatten oder gepragten Oberflache
Inventor: CHAUSSEE DOMINIC
IPC: B28B7/00
Filed: 2006-01-09
Abstract: A molding equipment and method to mold stackable inter-engaging bricks, blocks, stones and the like and bricks, blocks, stones and the like produced therewith are disclosed. The molding equipment comprises a main structure which contains individual cavities. Each cavity preferably has a middle structure to which a brick separating element can be attached. Without the brick separating element, each cavity can form two attached splittable bricks whereas with the brick separating element attached, each cavity can hold two individual smooth or embossed face bricks. The size and shape of the stackable inter-engaging bricks is such that once out of the mold but still in an uncured form, the brick can stand on its side without falling down, being damaged, buckling or being otherwise deformed during the manufacturing process.
Patent SI-2992292-T1 (SI)
Title: Adaptive cloaking method and device
Inventor: MULLER SYLVAIN
IPC: F41H3/00
Filed: 2014-05-02
Abstract: An adaptive masking method for an element in a field of operations. According to this method, at least one cover allowing to cover the element is implemented, the cover carrying at least one image generator network connected to an image synthesizer coupled to a camera. According to this method, the camera is positioned so as to cover both a portion of a background of the element and the entire cover, the image synthesizer controlling the at least one image generator network so as to minimize the contrast and optionally the frequency deviation between the background and the cover. The device implementing such a method is described.
Patent TR-201801747-T1 (TR)
Title: Kül parti̇külleri̇nde yanmamiş karbon i̇çeri̇ği̇ni̇n azaltilmasina yöneli̇k bi̇r si̇stem
Inventor: PRAKASH SHAMRAO KARVE
IPC: F23G5/00
Filed: 2016-08-05
Abstract: Açıklanan sistem, makine mühendisliği alanı ile ilgilidir. Sistem, külde mevcut karbon içeriğini azaltmaktadır. Kül partikülleri, bir ilk huniden bir karbon yakma ünitesine taşınır. Kül partikülleri bir ilk huni tarafından sağlanan bir sıvılaştırma ortamı ile karbon yakma ünitesinde sıvılaştırılır ve bu şekilde kül partiküllerinde bulunan yanmamış karbon yakılarak artık kül ve baca gazları üretilir. Bir siklon ayrıcı, baca gazlarının 7,5 mikrondan büyük kül partikülleri bulunan ilk kısmını ayırır ve baca gazlarının uçucu kül içeren ikinci kısmını iletir. İkinci kısımdaki ısı, bir ısı geri kazanımı ünitesiyle açığa çıkarılır. Baca gazlarının ikinci kısmı, baca gazlarındaki uçucu küllerin ayrılması için bir hava kirliliği kontrol ünitesine iletilir. Baca gazları, ikinci körük ile atmosfere verilir.
Patent DE-3486348-T2 (DE)
Inventor: CARTE MICHEL
IPC: G01F15/16
Filed: 1984-06-13
Granted: 1995-03-23
Abstract: The gas-meter has a measuring unit with casing forming two measuring compartments. Each of these is divided by a diaphragm into two chambers, while a distribution surface contains four ports, each connected to a chamber by an internal passage. A moving distributor is mounted on the surface, being coupled by levers to the diaphragms.   The casing comprises a central block, to which two side covers are fixed. The block incorporates all the components forming the internal passages.
Patent DE-3587604-T2 (DE)
Inventor: YOUNG MARK S
IPC: G06F3/06
Filed: 1985-12-19
Granted: 1994-03-24
Abstract: A method and apparatus for transferring data between a disk and a CPU is disclosed comprising a pair of toggling header buffers and a pair of toggling data buffers. In operation, data is transferred between a sector on a disk and one of the data buffers under the control of one of the header buffers. While the data in the header buffer is being transferred between the data buffer and a CPU, data is transferred between an adjacent sector on the disk and the other data buffer under the control of the other header buffer. The rate of transfer of data between the data buffer and the CPU is higher than the rate of transfer of the data between the disk and the other data buffer. This provides sufficient time to check the data transferred from and to the CPU for errors and to address a new sector on the disk prior to the completion of the data transfer of the previous sector between the disk and the data buffer. By means of the method and apparatus disclosed, all sectors in a track on a disk can be transferred between a disk and a CPU within a single revolution of the disk.
Patent SI-0750444-T2 (SI)
Title: Radiant heater and method for its manufacture
Inventor: WILDE EUGEN
IPC: H05B3/00
Filed: 1996-06-18
Abstract: The method involves pressing a heat barrier film (15) in a special form as a tablet (12) of disposable heat resistant material with an essentially flat surface. The heat conductor (17) is attached to the surface with partial embedding in the heat barrier material. The tablet is placed in an empty carrier shell (23) as a one-piece heat barrier. The partial embedding is performed in the vicinity of protruding attachment feet (22) of the heat conductor. The hear conductor is placed in an insertion tool (16) and pressed into the surface of the tablet with its embedded parts.
Patent DE-60002741-T2 (DE)
Inventor: CHEN YE-MON
IPC: C10G11/00
Filed: 2000-09-01
Granted: 2004-03-18
Abstract: A catalytic cracker riser reactor is connected to a regenerator standpipe through which hot, regenerated catalyst enters the riser bottom region. A hydrocarbon feed, such as gas oil, and dispersing gases, such as steam, are introduced through a single bottom entry nozzle assembly. The nozzle assembly comprises three concentrically arranged conduits. An inner conduit provides a passageway for a first dispersing gas and terminates in a first cap having at least one outlet passage for discharging the first dispersing gas in a generally radially outward and upward direction. The first conduit and first cap are enclosed by a second conduit and second cap, the annulus formed thereby providing a passageway for a liquid hydrocarbon feed. The second cap also has at least one outlet passage for discharging the mixture of hydrocarbon feed and first dispersing gas into the riser reactor in a radially outward and upward direction. A first dispersing gas enters the inner conduit and proceeds to the first cap into a mixing zone located in the vicinity of the discharge passage between the first and second caps. Hydrocarbon feed enters the second conduit, continues through an annulus to the second cap and is mixed with the first dispersing gas in the mixing zone, resulting in the formation of a fine two-phase mixture of small dispersed bubbles in heavy petroleum hydrocarbon liquid. As the fine two-phase mixture passes through the outlet passage into the riser reactor to contact with regenerator catalyst, the two-phase mixture suddenly expands, forming a fine atomization of heavy petroleum hydrocarbon feed with narrow droplet size evenly distributed across the riser reactor.
Patent DE-60003846-T2 (DE)
Inventor: BARON A
IPC: A61P9/10
Filed: 2000-10-27
Granted: 2004-06-03
Abstract: Disclosed is a process of making substituted pyrazoles (I) from substituted benzophenone hydrazones (II) with a variety of 1,3-bifunctional substrates (III) under acid conditions. The pyrazole compounds are useful for making pharmaceutical compounds. In said formula, wherein X is chosen from -CN and -C(O)-R3 wherein if X is CN then R3 in the product formula (I) is amino.
Patent DE-60007021-T2 (DE)
Inventor: REGGIANI GIUSEPPE
IPC: B65G57/16
Filed: 2000-04-13
Granted: 2004-06-03
Abstract: The apparatus comprises a screw device (10) arranged to deliver the articles one at a time, in a manner spaced from the others, after withdrawing them from a vertical pile resting on it, means for counting the articles delivered by the screw device (10) and, downstream thereof, a continuous track (20) along which the articles slide in a stacked arrangement and which leads the stacks containing a predetermined number of articles to a final station (50) in which the stacks are positioned horizontally or inclined; finally a rotary device (30) accompanies the stacks of articles of predetermined number and urges them one at a time along said track (20) from the point in which they leave the screw device (10) to the final station (50). <IMAGE>
Patent DE-60011406-T2 (DE)
Inventor: WOLFF SIEGFRIED
IPC: A61G5/10
Filed: 2000-03-27
Granted: 2005-06-30
Abstract: A device for collecting urine includes a container kept at vacuum, an interface locatable at the urethral opening of a person and a pump operable to create a vacuum within the container. A sensor senses the presence of urine at the interface and opens a valve to allow the pumping of urine from the interface to the container.
Patent DE-60016185-T2 (DE)
Inventor: IKUTA YOSHIAKI
IPC: G03F1/62
Filed: 2000-09-13
Granted: 2006-03-02
Abstract: It is characterized by having a pellicle sheet made of a synthetic quartz glass having an OH group concentration of at most 100 ppm and containing substantially no oxygen deficient defect. It is particularly preferred that the OH group concentration is at most 10 ppm, and the internal transmittance is at least 80 %/cm at a wavelength of 157 nm. <IMAGE>
Patent DE-60021103-T2 (DE)
Inventor: ADAMS DAVID CHARLES
IPC: B01J19/24
Filed: 2000-10-06
Granted: 2006-05-18
Abstract: An emulsion polymerization process using a reactor having one or more circulation loops with one or more inlets for raw material, one or more inlets for a carrier liquid in which the polymer to be formed is insoluble, and one or more outlets for polymer emulsion; and one or more driving means for continuously circulating the reactor charge within the circulation loop. An emulsion polymerization process includes charging the reactor with raw material, including monomers, and with the carrier liquid, including stabilizers, and optionally other additives; then continuously feeding the loop reactor with the raw material and with the carrier liquid; and continuously withdrawing part of the reactor charge from the reactor at a rate equal to the rate of total raw material and carrier liquid feeding. The carrier liquid, or water phase, consists wholly or partially of washings used for washing one or more parts of the same or a different polymerization reactor and/or associated equipment. The invention also pertains to a loop reactor for carrying out such process.
Patent DE-60022722-T2 (DE)
Inventor: FIELDING ROBERT MICHAEL
IPC: F24F8/15
Filed: 2000-11-15
Granted: 2006-06-29
Abstract: A system for treating air for supply to an enclosed space in which it is to be breathed, comprises an inlet through which air can enter the system from atmosphere for supply to the enclosed space, and a regenerative adsorption assembly comprising at least two chambers which contain an adsorbent material, arranged so that air flowing in the inlet for supply to the enclosed space can pass through one of the chambers for adsorption of contaminants before supply to the enclosed space while adsorbent material in another of the chambers is purged of adsorbed contaminants. A recirculation path is provided for supplying air from the enclosed space to the inlet to be mixed with air from atmosphere before it is supplied to the enclosed space. The system includes means for adjusting the resistance to flow of air through the recirculation path according to the resistance that is provided to the flow of air from atmosphere into the enclosed space.
Patent DE-60023894-T2 (DE)
Inventor: LONG T
IPC: E04C2/04
Filed: 2000-06-16
Granted: 2006-07-27
Abstract: Precast insulated concrete wall panels are made by pouring a first concrete layer into a form. An insulation layer is then supported above the first concrete layer so as to create a space therebetween. The second concrete layer is then poured on top of the insulation layer before the first concrete layer has cured. Connectors are anchored in the first and second concrete layers so as to tie the layers together. After the first and second concrete layers have cured, the wall panels can be lifted, transported, and assembled into a wall structure. An intermediate layer of concrete can be poured into the air gap of the wall panels such that the panels define the form for the intermediate concrete layer and become an integral part of the wall structure. The wall structure may extend below or above grade and may be multi-tiered. The edges of the wall panels are contoured so as to interlockingly matingly engage when assembled into the wall structure. Notches may be provided in the upper edge of the wall panels so as to receive floor or roof joists.
Patent DE-60024638-T2 (DE)
Inventor: RABE ELLIOT
IPC: A61K8/89
Filed: 2000-08-17
Granted: 2006-08-17
Abstract: Disclosed are stabilized electrostatically-sprayable topical compositions and methods of treating the skin by electrostatic application of such compositions. The compositions comprise:a) from about 2% to about 90% of a liquid insulating material;b) from about 2% to about 90% of a conductive material;c) from about 0.1% to about 35% of a particulate material which is insoluble and immiscible in the composition; andd) from about 0.5% to about 30% of a thickener for stabilizing the composition.The liquid insulating materials and conductive materials present in the composition are sufficiently miscible or soluble in the composition such that they are in substantially one phase.
Patent DE-60026172-T2 (DE)
Inventor: EMERICKS ANDERS
IPC: H04M19/00
Filed: 2000-12-15
Granted: 2006-10-12
Abstract: A subscriber line interface circuit ( 1 ') for supplying line current (IL') to a two-wire transmission line connected to a load (RL'), comprises a single current amplifier ( 3 '). That single current amplifier ( 3 ') is to be connected with its output terminal to one (B') of the wires (A', B') of the transmission line, while the other wire (A') of the transmission line is to be connected to a voltage source (V 1 ') that can be provided within the subscriber line interface circuit ( 1 ') or external thereto.
Patent DE-60031004-T2 (DE)
Inventor: CORNELIUS S
IPC: H04L29/06
Filed: 2000-11-09
Granted: 2007-02-01
Abstract: An electronic security scheme and security system for a communications network facilitates the preventing of unauthorized access to an internal resource of an entity's internal computer system. A server includes a first set of ports for communication between an external communications network and the server. The server has a second set of ports for communications between an internal communications network and the server. A first firewall is interposed between the server and the external communications network. The first firewall is coupled to the first set of ports to provide at least one interconnection between the first set of ports and the external communications network. A second firewall is interposed between the server and the internal communications network. In one embodiment, the second firewall is coupled to the second set of ports to provide in a nonnegative integer number of interconnections between the second of set ports and the internal communications network.