baber/WOPTO huggingface dataset:
Patent EP-3797105-A1 (EP)
Title: Methods and compounds for the treatment of genetic disease
Inventor: ANSARI ASEEM
IPC: C07D403/14
Filed: 2019-05-22
Abstract: The present disclosure relates to compounds and methods for modulating the expression of  dmpk, atxnl, atxn2, atxn.3, cacnala, atxn7, ppp2r2br tbp, htt, jph3r ar , or  atnl  and treating diseases and conditions in which  dmpk, atxnl, atxn2, atxn3, cacnala, atxnl, ppp2r2b, tbp, htt, jph3, ar , or  atnl  plays an active role. The compound can be a transcription modulator molecule having a first terminus, a second terminus, and oligomeric backbone, wherein: a) the first terminus comprises a DNA-binding moiety capable of noncovalently binding to a nucleotide repeat sequence CAG or CTG; b) the second terminus comprises a protein-binding moiety binding to a regulatory molecule that modulates an expression of a gene comprising the nucleotide repeat sequence CAG or CTG; and c) the oligomeric backbone comprising a linker between the first terminus and the second terminus.
Patent EP-3579086-A1 (EP)
Inventor: ZHOU HAITAO
IPC: G06F3/01
Filed: 2019-02-18
Abstract: Provided are a method and apparatus for turning on a screen, a mobile terminal and a storage medium. The method comprises that: when a change in a moving state of a mobile terminal meets a preset unlocking condition, a structured light image sensor is activated for imaging; a depth map obtained by the imaging of the structured light image sensor is acquired; a face depth model is constructed according to the depth map; a position of pupils is identified from the face depth model; and when the position of the pupils is within a specified region of eyes, the screen of the mobile terminal is controlled to turn on.
Patent EP-3827413-A1 (EP)
Title: Depth ray layer for reduced visual noise
Inventor: ESSELSTROM TYLER P
IPC: G06T15/00
Filed: 2019-06-19
Abstract: The described technology includes a depth ray shader stored in memory and executable to receive a depth map defining a depth in association with each pixel in a three-dimensional scene and define a color gradient between a first pixel value and a second pixel value, wherein each sequential step in the color gradient between the first pixel value and the second pixel is assigned to a corresponding depth of increasing magnitude relative to a reference point. The depth ray shader is further executable to provide an instruction to a graphics engine to cause the graphics engine to apply a depth ray layer to a select portion of the three-dimensional scene, the depth ray layer altering each pixel in the selected portion to assume a pixel value defined within the color gradient to correspond to a depth of the pixel specified by the depth map.
Patent EP-3837929-A1 (EP)
Inventor: ADRIAN JASON DAVID
IPC: H05K7/14
Filed: 2019-06-25
Abstract: A server node is provided that includes a processor and a network interface controller mounted in a chassis configured to be inserted into a server node slot of a server node grid. The chassis includes a blind-mate connector system on a back side that includes a blind-mate power connector and a blind-mate network connector configured to blind-mate with a corresponding blind-mate power connector and a corresponding blind-mate network connector of the server node slot of the server node grid. As the server node is inserted into the server node slot, the blind-mate power connector is configured to blind-mate with the corresponding blind-mate power connector of the server node slot before the blind-mate network connector blind-mates with the corresponding blind-mate network connector of the server node slot, such that the blind-mate power connector provides alignment guidance for the blind-mate network connector.
Patent EP-3827325-A1 (EP)
Inventor: KIEMELE KENNETH LIAM
IPC: G06F3/0481
Filed: 2019-06-20
Abstract: Examples are disclosed that relate to refining virtual mesh models through physical contacts. For example, a hand-mounted mobile device, such as a wearable glove, may be used to create and/or emphasize specific points within a virtual mesh model of a physical environment. An indication of physical contact of an interface of the mobile device with a physical object may be obtained via a touch sensor of the mobile device. A location and/or an orientation of the interface of the mobile device during the physical contact with the physical object may be identified based on sensor data obtained from one or more positioning sensors. Location data indicating the location may be stored in a data storage device from which the location data may be referenced. In an example, refinement of a virtual mesh model of a physical environment containing the physical object may be prioritized based on the location data.
Patent EP-3741421-A1 (EP)
Title: Implantable microneedle and manufacturing method therefor
Inventor: YANG SEUNG YUN
IPC: A61M37/00
Filed: 2019-01-17
Abstract: The present invention provides an implantable microneedle and a manufacturing method therefor. An implantable microneedle according to the present invention comprises a coating layer for covering at least one part of the surface of a tip part of the microneedle. When exposed to moisture, the coating layer can be separated from the tip part of the microneedle and thus be implanted.
Patent EP-3827619-A1 (EP)
Title: Transmission of network slicing constraints in wireless networks
Inventor: ANDREWS DANIEL
IPC: H04W48/18
Filed: 2019-07-19
Abstract: A 5G network communicates per-slice constraints for QoS parameter values froma centralized unit (CU) to a MAC scheduler of a distributed unit (DU). The CU communicates these per-slice constraints, rather than or in addition to per-DRB constraints, to the MAC scheduler over the CU/DU interface. In some implementations, the CU/DU interface is an F1 air interface as defined in specification 38.473 in the 3GPP standard. In some implementations, the DU provides per-slice performance feedback over the CU/DU interface. Based on such feedback, the CU may adjust the per-slice QoSconstraints.
Patent EP-3815353-A1 (EP)
Inventor: LIU XINQIAO
IPC: H04N5/355
Filed: 2019-06-28
Abstract: In one example, a method comprises: enabling a photodiode to, in response to incident light, accumulate residual charge, and to transfer overflow charge to a first charge storage device and a second charge storage device when the photodiode saturates; disconnecting the second charge storage device from the first charge storage device; enabling the photodiode to transfer the residual charge to the first charge storage device to cause the charge sensing unit to output a first voltage; quantizing the first voltage to generate a first digital value to measure the residual charge; connecting the second charge storage device with the first charge storage device to cause the charge sensing unit to output a second voltage; quantizing the second voltage to generate a second digital value to measure the overflow charge; and generating a digital representation of the incident light intensity based on the first digital value and the second digital value.
Patent EP-3959301-A1 (EP)
Inventor: SEGUES BERTRAND
IPC: C12M1/02
Filed: 2019-04-25
Abstract: The invention relates to a method for characterizing the activity of a culture comprising microalgae, the method comprising the steps of: supplying a sample of the culture from a bioreactor to a chamber fluidically connected to the bioreactor; illuminating the sample in the chamber; measuring the concentration of dissolved oxygen in the sample in order to determine a rate of oxygen production by the illuminated sample. The invention also relates to a device and an apparatus for characterizing a culture comprising microalgae.
Patent EP-3817801-A1 (EP)
Inventor: CAMPBELL SUSAN ROSEMARY
IPC: A61M1/00
Filed: 2019-07-02
Abstract: Systems, catheters, and methods for accessing and treating along the central nervous system are disclosed. An example method may control operation of a pump (104) of pump/filtration system (100) to facilitate removing cerebrospinal fluid from a patient, filtering the cerebrospinal fluid with a filter module (112) to remove waste product, and returning the filtered cerebrospinal fluid to the patient. Operation of the pump may be adjusted based on a value related to a measure sensed by a sensor (108) in communication with a lumen carrying cerebrospinal fluid through the filtration system.
Patent EP-4005023-A1 (EP)
Title: Method and apparatus to selectively utilize antennas of an antenna array
Inventor: BARABASH DARRELL WILLIAM
IPC: H04B7/06
Filed: 2019-07-26
Abstract: A method, apparatus and computer program product are provided disable one or more antennas of an antenna array in order to achieve a predefined objective while selectively utilizing the remainder of the antennas of the antenna array. The one or more antennas to be disabled are selected in a manner to avoid appreciable impact to the fidelity of the resulting array radiation pattern. For example, the method, apparatus and computer program product may disable certain antenna elements based upon the distance of the antenna elements from a predefined location relative to the antenna array, such as the distance from the center of the antenna array, and may selectively utilize the remainder of the antenna elements such that an active portion of the antenna array approximates a circular array which results in an array radiation pattern for which the fidelity is maintained.
Patent EP-3860911-A1 (EP)
Inventor: HAGAN CHRIS
IPC: B64C27/20
Filed: 2019-08-09
Abstract: A drone docking system (10) for multicopter drone (50) comprises a docking station (20) having a receiver (26). The receiver (26) is adapted to connect to a docking formation (52) mounted atop the drone (50) such that when the drone (50) is docked with the docking station (20), the drone (50) is suspended from and below the docking station (20). A fail-safe mechanical connection (56, 32) is provided to connect the docking formation (52) to the receiver (26). One or more electromagnets (34, 58) may be used to connect the docking formation (52) to the receiver (26), which electromagnets (34, 58) are suitably controllable to provide a smooth transition between docked and free-flight states of the drone (50) and optionally to guide the docking formation (52) into alignment with the receiver (26). The drone (50) suitably has a payload rendering it useful for surveillance and crime prevention/detection purposes.
Patent EP-3759079-A1 (EP)
Inventor: JOHN VARGHESE
IPC: C07D405/10
Filed: 2019-02-28
Abstract: The present disclosure provides various compounds, compositions, and methods of BACE inhibition that interact with both BACE and APP to increase selectivity of the inhibitor. Compounds presented herein exhibit desirably low IC50 values and permeability across the blood-brain barrier.
Patent EP-3608323-A1 (EP)
Inventor: XU WEIPING
IPC: A61K31/335
Filed: 2019-03-01
Abstract: The present invention relates to pyran-fused ring compounds, preparation methods thereof and use thereof, especially to pyran-fused ring compounds usable for preparing Halichondrin, Eribulin, or analogues thereof, preparation methods thereof and use thereof. Use of any of the compounds of formula (I) to (XIII) of the present invention in preparation of Halichondrin B, Eribulin, analogues thereof or C1-C13 moieties thereof. Provided in the present invention are intermediates usable for preparing Halichondrin B, Eribulin, or analogues thereof, especially the key product of C1-C13 moieties, preparation methods thereof and use thereof. The starting material for the synthesis pathway of the present invention is inexpensive and readily available with sustainable source and reliable quality. Since the structural characteristics of the reactants of theirself are made full use in choosing the method of constructing the chiral centers, the efficiency in the synthesis is considerably increased, the difficulty in and the risk on quality control of the product are reduced; and using a highly toxic and expensive high-valent osmium catalyst is avoided, which have the cost and environmental friendliness significantly improved.
Patent EP-4021861-A1 (EP)
Inventor: GAZZELLI MAURO
IPC: C02F1/32
Filed: 2019-08-30
Abstract: A device (1) for distributing mineralized water, said device comprising: - an inlet (3), for loading water from an external source (100); - a distillation unit (2), connected to the inlet (3) and configured to provide a distillation of an amount of water at least partially through heating, wherein said distillation unit (2) in turn comprises, or is operatively connected to, at least an heater (4) configured for providing heat in an amount sufficient to heat the amount of water at least up to a boiling temperature; - a water distributor (5) configured for transferring a predetermined amount of distilled water (D) extracted from the distillation unit (2), to a removable container (10), the water distributor (5) being provided with an outlet nozzle or aperture (6) configured to face in use on said container (10); - a mineralization unit (7) interposed between the distillation unit (2) and the outlet nozzle or aperture (6), said mineralization unit (7) being configured for accessing the inner cavity of a disposable capsule (20), containing a mineralized fluid solution or powder (M) in said cavity, for extracting at least part of said mineralized fluid solution or powder (M) from the capsule (20) and/or being configured for emptying the capsule (20) from the mineralized fluid solution or powder (M), and transferring at least part of the mineralized fluid solution or powder (M) from the capsule (20) to the water distributor (5); - the device, optionally through the water distributor (5), being configured to mix the mineralized fluid solution or powder (M) with the predetermined amount of distilled water (D) transferred by the water distributor (5) to the removable container (10).
Patent EP-3830445-A1 (EP)
Inventor: HEINRICH ULF
IPC: H02B1/54
Filed: 2019-08-27
Abstract: The invention relates to a shock absorber (1) for a high-voltage device. The shock absorber (1) comprises a rod element (5) having an outer thread (19) running about a longitudinal axis (17) of the rod element (5), two holders (7, 8) which support the rod element (5), a rotational element (9) which runs like a ring about the rod element (5) and has an inner thread (21) engaging into the outer thread (19), and a carrier element (3) which is mounted on the rotational element (9) in such a way that rotations of the rotational element (9) about the longitudinal axis (17) decouple from the carrier element (3).
Patent EP-3771004-A1 (EP)
Title: Binder composition for nonaqueous secondary battery electrode, conductive material paste composition for nonaqueous secondary battery electrode, slurry composition for nonaqueous secondary battery electrode, nonaqueous secondary battery electrode, and nonaqueous secondary battery
Inventor: MURASE TOMOYA
IPC: H01M4/139
Filed: 2019-03-14
Abstract: Provided is a binder composition for a non-aqueous secondary battery electrode that can form a slurry composition for a non-aqueous secondary battery electrode having excellent viscosity stability and a non-aqueous secondary battery having excellent cycle characteristics. The binder composition for a non-aqueous secondary battery electrode contains: a polymer that includes a monomer unit including a functional group that is bondable with a cationic group and a (meth)acrylic acid ester monomer unit; and an organic compound that includes at least two cationic groups. The binder composition for a non-aqueous secondary battery electrode has a viscosity change rate of 400% or less when left at rest at a temperature of 60°C for 30 days.
Patent EP-3658814-A1 (EP)
IPC: F16M11/18
Filed: 2019-03-18
Abstract: A load-stabilizing apparatus includes a load-connecting member configured to carry a load, a parallelogram mechanism connected to the load-connecting member, and a stabilizing motor drivingly connected to the parallelogram mechanism. The stabilizing motor is configured to drive the parallelogram mechanism to deform, such that the parallelogram mechanism drives the load-connecting member to move.
Patent EP-3856766-A1 (EP)
Title: Formulations of glucagon-like-peptide-2 (glp-2) analogues
Inventor: GIEHM LISE
IPC: A61K38/26
Filed: 2019-09-27
Abstract: Liquid formulations of GLP-2 analogues that make them suitable for long term storage as liquids and/or that makes them especially suitable for delivery by a drug delivery device are described. Solid compositions comprising acetate salts of glucagon-like peptide 2 (GLP-2) analogues useful for making the liquid formulations are also described. The development of these liquid formulations is based on the finding that acetate present in the formulation that originates from the GLP-2 analogues has an effect on the viscosity of the formulation, that during long term storage at 2-8°C of GLP-2 analogues, the concentration dependence for covalent oligomer formation is inversely dependent on increasing concentration of the GLP-2 analogue, and that GLP-2 analogues used in the formulations are not compatible with phosphate buffer commonly used in the prior art to reconstituted powdered or lyophilized GLP-2 compositions.
Patent EP-3778180-A1 (EP)
Inventor: IWATA TOSHIO
IPC: B29C45/18
Filed: 2019-03-27
Abstract: [Object]A method is provided which produces an injection molded article that includes a fiber-reinforced resin composition and attains a high fiber content and superior mechanical characteristics, in particular, impact resistance.[Solution]The method for producing an injection molded article including a highly-filled fiber-reinforced resin composition includes a step of charging a first resin feedstock including a thermoplastic polymer (A) into an injection molding machine through a first inlet port; a step of charging a second resin feedstock into the injection molding machine through a second inlet port disposed downstream of the first inlet port, the second resin feedstock including a masterbatch that includes long fibers (D) impregnated with a resin mixture including a thermoplastic polymer (B) and an acid-modified polyolefin (C); a step of melt-kneading the first resin feedstock and the second resin feedstock together in the injection molding machine to give a fiber-reinforced resin composition melt; and a step of injection molding the fiber-reinforced resin composition melt in a mold, the first resin feedstock being charged intermittently or continuously from the start to the end of the charging of the second resin feedstock.
Patent EP-3779004-A1 (EP)
Inventor: SHIMADA HIROKI
IPC: A41D31/00
Filed: 2019-03-25
Abstract: A task is to provide a cloth which is advantageous in that the cloth has extremely excellent flame retardancy, and further has excellent washing shrinkage resistance and excellent hand as well as excellent antistatic properties, preferably in that the whole of the cloth can be uniformly dyed, and a fiber product, and the task is achieved by obtaining a cloth using a spun yarn which comprises a meta-type wholly aromatic polyamide fiber, a modacrylic fiber, and a conductive fiber.
Patent EP-3779932-A1 (EP)
Inventor: KOMIYAMA TAKAFUMI
IPC: H04L9/32
Filed: 2019-03-31
Abstract: The present invention simplifies the signature handling for a block for which consensus was formed in a blockchain network which requires signatures from a plurality of nodes to form consensus for the adoption of a block. After completion of the setup, a first node 110 sends a first message including a generated block to N nodes (S301). Each node evaluates the validity of the block on the basis of the rule for consensus formation (S302). If the block is valid, the node sends, to each node, a second message which includes a signature si, by a secret key share f(x<sub>i</sub>), with respect to a hash value h of the block for which consensus is to be formed (S303-1). After k signatures are collected at jth node, the node merges these signatures to generate a signature corresponding to a public key PK (S304). A block for which consensus is to be formed has a signature SK·h appended thereto and is added to the blockchain of each node (S306).
Patent EP-3866931-A1 (EP)
Inventor: LEHMANN FREDRIK
IPC: A61P35/00
Filed: 2019-10-17
Abstract: La présente invention concerne un composé de la formule (I), ou son sel de qualité pharmaceutique (formule I), chaque R 1 -R 30  étant indépendamment sélectionné dans le groupe constitué de H et du deutérium, et au moins l'un de R 1 -R 30  étant le deutérium avec un niveau isotopique supérieur au niveau isotopique naturel du deutérium. L'invention concerne également des compositions pharmaceutiques contenant les composés, ainsi que les utilisations des composés.
Patent EP-3871068-A1 (EP)
Inventor: EITEN JOSHUA BENJAMIN
IPC: G06T19/00
Filed: 2019-10-16
Abstract: The construction of virtual-reality environments is more efficient with adjustable virtual user input devices that accommodate user physical limitations. Adjustable virtual user input devices can be adjusted along pre-established channels, which can be anchored to specific points in virtual space, including a user's position. Adjustable virtual user input devices can be bent in a vertical direction, bent along a horizontal plane, or other like bending, skewing, or warping adjustments. Elements, such as individual keys of a virtual keyboard, can be anchored to specific points on a host virtual user input device, such as the virtual keyboard itself, and can be bent, skewed, or warped in accordance with the adjustment being made to the host virtual user input device. The adjustability of virtual user input devices can be controlled through handles, which can be positioned to appear as if they are protruding from designated extremities of virtual user input devices.
Patent EP-3782070-A1 (EP)
Inventor: DEROO RICHARD
IPC: G06F119/22
Filed: 2019-10-31
Abstract: A method for performing a design rule check of a computer aided design (CAD) file corresponding to a geometry of a tool for use in a process for making an article from a starting material. Design rules defined to avoid a geometry of the tool documented as causing an inefficiency in a non-printing or non-platemaking operation of the process are stored in a computer. A design rule checking (DRC) module of the computer processes the CAD file relative to the stored design rules, identifies violations, automatically suggests design changes responsive to each violation, receives a user input responsive to suggested design changes, and modifies the CAD file in response to the user input. Non-transitory computer readable media containing code for implementing the method and related CAD systems are also described.
Patent EP-3887300-A1 (EP)
Title: Montagevorrichtung und verfahren zum automatisierten bohren von löchern in gebäudewände mit einer automatisierten erkennung von verschleissmarken am bohrer
Inventor: CAMBRUZZI ANDREA
IPC: B25J9/16
Filed: 2019-11-12
Abstract: Die Erfindung betrifft eine Montagevorrichtung (14) und ein Verfahren zum automatisierten Bohren von Löchern (15) in Gebäudewände. Die Montagevorrichtung (14) verfügt über eine Bohrvorrichtung (40) mit einem Bohrer (41), eine optische Erfassungseinrichtung (35) zur Erfassung eines digitalen Bilds (42) zumindest eines Teils des Bohrers (41) der Bohrvorrichtung (40) und eine Steuerungseinrichtung (37) zur Ansteuerung der Bohrvorrichtung (40) und der optischen Erfassungseinrichtung (35). Die Steuerungseinrichtung (37) ist dazu vorgesehen, das genannte digitale Bild (42) auszuwerten und dabei einen Zustand des Bohrers (41) zu beurteilen.