baber/WOPTO huggingface dataset:
Patent DE-69637001-T2 (DE)
Inventor: MARTIN MARK T
IPC: C07K16/00
Filed: 1996-06-06
Granted: 2007-12-06
Abstract: Electrochemiluminescent-labels and enzyme substrates, which preferably are conjugated, are used in immunoassays and electrochemiluminescence is generated catalytically. In conventional electrochemiluminescence immunoassays, an anti-analyte antibody molecule can give rise to typically 6-8 electrochemiluminescence-active ruthenium atoms, while in the present invention, each enzyme-labeled anti-analyte molecule can give rise to thousands of electrochemiluminescence-active ruthenium atoms per second. An exemplary immunoassay is based on a catalytic process employing beta-lactamase-conjugated anti-analytes which enzymatically hydrolyze electrochemiluminescent-labeled substrates, making them strongly electrochemiluminescent. The electrochemiluminescence signal generated by each anti-analyte molecule (i.e., each analyte molecule) is much greater than with the conventional method. Accordingly, greater sensitivity can be gained in the measurement of low concentrations of a given immunoassay analyte.
Patent DE-69704613-T2 (DE)
Inventor: MAUBRU MIREILLE
IPC: C09B1/51
Filed: 1997-05-20
Granted: 2001-08-30
Abstract: PCT No. PCT/FR97/00885 Sec. 371 Date May 20, 1998 Sec. 102(e) Date May 20, 1998 PCT Filed May 20, 1997 PCT Pub. No. WO97/44004 PCT Pub. Date Nov. 27, 1997The invention discloses a capillary dyeing composition comprising at least one direct dye, wherein the composition further comprises a cross-linked polymer with acrylic units and alkyl C10-C30 acrylate units. The invention also discloses the use of cross-linked polymer with acrylic units and alkyl C10-C30 acrylate units in or for the production of a capillary dyeing composition comprising at least one direct dye, to improve the tinctorial power of the composition, particularly after storage at below about 10 DEG  C., and in particular at about 4 DEG  C. The invention also discloses a method for preserving the tinctorial power of the composition, particularly after storage at below about 10 DEG  C., of a dyeing composition containing at least one direct dye, wherein an effective amount of the cross-linked polymer is added to the composition.
Patent DE-69708935-T2 (DE)
Inventor: GUENTHER HERBERT
IPC: B29C45/27
Filed: 1997-12-19
Granted: 2002-04-18
Abstract: A hot runner nozzle structure provides insulation to reduce heat transfer to a utilizing tool and to increase accuracy of temperature measurement and control. A shaft foot (48) of extremely low heat conductivity is used to separate a point of contact between a feed tube shaft (17) and the tool (27). The shaft foot (48) may be formed of titanium for example. An insulating cap (53) of extremely low heat conductivity surrounds the shaft foot (48) in the vicinity of the nozzle tip (26). The cap (53) may be formed of PEEK or of titanium for example. Gaps may be provided between the insulating cap (53) and shaft foot (48) and/or between the shaft foot (48) and feed tube shaft (17). In an alternate embodiment having smaller dimensions, an insulating ring (54) is provided at the end of the feed tube shaft. The structure, combined with a positioning sleeve surrounding the feed tube shaft, permits placing a heat sensor (34) extremely close to the nozzle tip (26) in order to obtain more accurate temperature control. <IMAGE>
Patent DE-69708943-T2 (DE)
Inventor: DEL FABBRO CLAUDIO
IPC: F22B1/28
Filed: 1997-01-22
Granted: 2002-04-25
Abstract: An atmospheric pressure stem generator associable to a cooking oven comprises a water reservoir (1) and electric heater elements (22). The reservoir (1) is substantially box-shaped and has one side closed by at least one removable wall plate (3), so that the interior of the reservoir (1) is accessible for servicing. The heater elements (22) fixedly secured to the removable wall plate, permitting calcine deposits to be readily removed therefrom. The steam generator further comprises a rod (17), preferably associated to an emergency steam outlet pipe (15), and extending into the reservoir (1) down to below the lowest water elevel therein. Extraction of the rod permits the user to ascertain the amount of calcine deposits and the presence of a sufficient water supply. Object/Advantage: Ensuring maximum reliability of the steam generator. <IMAGE>
Patent DE-69711746-T2 (DE)
Inventor: KOSKINEN JUKKA
IPC: B05C5/02
Filed: 1997-02-18
Granted: 2002-08-14
Abstract: The invention relates to an assembly for preventing plugging of a narrow, slot-orifice-type jet nozzle 6 used in a paper and board coater in which jet nozzle extends over the entire cross-machine width of the web being coated, said coater comprising an application chamber (11), a coating mix infeed channel (10) connected thereto and a slot orifice (6) as well as at least one infeed port for feeding the coating mix into said application chamber (11). According to the invention, an easily cleanable strainer element (12) is placed close to the applicator apparatus, said strainer serving to separate aggregates of the coating mix that otherwise could plug the slot orifice (6). <IMAGE>
Patent DE-69726540-T2 (DE)
Inventor: WILKINS ANTHONY JOHN JOSEPH
IPC: F01N3/02
Filed: 1997-09-30
Granted: 2004-09-30
Abstract: An emission control system for internal combustion engines which emit carbonaceous soot particles, comprises a first catalyst effective to oxidise NO to NO2 and a second catalyst effective at least to oxidise hydrocarbons, carbon monoxide and volatile organic fractions, each catalyst being supported on a honeycomb flow-through monolith comprising a plurality of cells, each defined by a cell wall, whereby soot particles trapped on or within said second catalyst monolith are combusted in the NO2-containing gas from said first catalyst, and wherein the first catalyst is supported on a flexible metal monolith whereby flexing and/or vibration of the honeycomb cell walls serves to minimise the collection of soot particles thereon. <IMAGE>
Patent DE-69728377-T2 (DE)
Inventor: POWERS B
IPC: C12N9/04
Filed: 1997-01-09
Granted: 2005-01-20
Abstract: Mutants of 2,5-diketo-D-gluconic acid reductase A an enzyme used to produce 2-keto-L-gluconic acid, a precursor of ascorbic acid (vitamin C), are prepared by site-directed mutagenesis. These mutants may exhibit one or more of the following characteristics: improved temperature stability, increased resistance to substrate inhibition, increased turnover of the substrate by the enzyme and increased affinity for the substrate.
Patent DE-69737326-T2 (DE)
Inventor: CHAMBON PIERRE
IPC: C07K16/18
Filed: 1997-07-11
Granted: 2007-11-22
Abstract: The present invention concerns a nuclear receptor (NR) transcriptional mediator. More specifically, isolated nucleic acid molecules are provided encoding transcriptional intermediary factor-2 (TIF2). Recombinant methods for making TIF2 polypeptides are also provided as are TIF2 antibodies. Screening methods are also provided for identifying agonists and antagonists of the activation function AF-2 of nuclear receptors, for identifying agonists and antagonists of the AD1 activation domain activity of TIF2, and for identifying agonists and antagonists of the AD2 activation domain activity of TIF2.
Patent DE-69801224-T2 (DE)
Inventor: KERNEVEZ NELLY
IPC: C30B11/00
Filed: 1998-05-15
Granted: 2002-05-16
Abstract: The invention concerns a device for the solidification and continuous control of crystal growth in an electrically conductive doped material or alloy, based on a liquid or a molten bath, for continuously monitoring crystal growth in said doped material or alloy, in particular for continuously monitoring the dope content in the doped material or the alloyed element content in the alloy. The device is characterised in that it has two cavities using the "Seebeck Monogradient" process whereby the means for electrically short circuiting a first liquid of the non-doped material or the pure unalloyed element in thermal equilibrium with a first solid thereof, and a second liquid of said doped material or of said alloy in thermal equilibrium with a second solid thereof, consist in an isothermal and conductive passage with reduced dimension, connecting the two cavities.
Patent DE-69805700-T2 (DE)
Inventor: FLASSAYER CLAUDE
IPC: H01L31/02
Filed: 1998-03-04
Granted: 2003-11-06
Abstract: The system (2) has a luminous source (4) and a photo-sensitive sensor (6) designed to be displaced with respect to each other. The sensor is designed to generate, when it is illuminated by the beam (8) from the source, an electric signal representing the position of the source with respect to the sensor. The sensor has a number of layers deposited on a support (10) with a transparent high resistance layer (12) designed to form a potentiometer track and a photo-sensitive layer (14) designed to deliver electrical charges when it is illuminated by the beam from the source. A metallic layer (16) is designed to collect the electrical charges generated by the photo-sensitive layer. The photo-sensitive layer (14) has a PIN junction deposited between the high resistance layer (12) and the metallic layer (16) so as to form a photo-diode.
Patent DE-69811502-T2 (DE)
Inventor: PAASONEN A
IPC: D21G1/02
Filed: 1998-06-11
Granted: 2003-07-24
Abstract: A covered roll structure employed in the manufacture of a paper machine roll comprises a core roll having a substantially cylindrical outer surface, a sleeve of removable material surrounding the core roll outer surface, a sleeve of compressible material surrounding the sleeve of removable material, and a sleeve of polymeric material surrounding the sleeve of compressible material and the sleeve of removable material.
Patent DE-69817598-T2 (DE)
Inventor: HARTNAGEL PHILIP
IPC: B60H1/00
Filed: 1998-10-30
Granted: 2004-03-18
Abstract: A tube assembly for an auxiliary heating and air conditioning system includes an inner tube extending longitudinally, an outer tube extending longitudinally and disposed over the inner tube, the outer tube including a plurality of ribs for locating the inner tube approximately concentric to the outer tube, at least one connector tube, and at least one connector interconnecting the at least one connector tube and the outer tube to allow fluid flow between the inner tube and the outer tube.
Patent DE-69820130-T2 (DE)
Inventor: SHAMSHOUM EDWAR S
IPC: C08F10/00
Filed: 1998-02-05
Granted: 2004-07-29
Abstract: An olefin polymerization process in which at least two introductions of hydrogen are made during the olefin polymerization reaction. Suitable catalysts include metallocenes of the general formula (Cp)<sub>m</sub>TiX<sub>n</sub>, wherein Cp is a substituted or unsubstituted cyclopentadienyl ring, X is a halogen, m=1-2, n=2-3, and wherein m+n=4, and conventional Ziegler-Natta catalysts blended with or modified by such metallocenes.
Patent DE-69825583-T2 (DE)
Inventor: MARTINEZ ALONSO CARLOS
IPC: C12N15/02
Filed: 1998-03-19
Granted: 2005-08-11
Abstract: The present invention relates to a method for determinating cytokine receptor, especially growth hormone receptor (GHR), activation, by the use of an antibody capable of discriminating between an activated and an inactive cytokine receptor conformation, especially GHR or growth hormone binding protein (GHBP) conformation, the method comprising: contacting the antibody and the cytokine receptor to form a complex, contacting a candidate ligand to the complex, measuring the antibody binding to inactive cytokine receptor and thereby discriminating between an activated and an inactive conformation. The invention also relates to an antibody directed to the hinge spanning subdomains I and II of the growth hormone receptor extracellular region and which is capable of discriminating between an activated and an inactive receptor conformation. The invention also relates to the use of the antibody for e.g. characterization of growth hormone receptor interactions and for screening for compounds stabilising die dimerization of GHR.
Patent DE-69829479-T2 (DE)
Inventor: CHERIAN GEORGE
IPC: A23L7/109
Filed: 1998-08-18
Granted: 2005-07-28
Abstract: A process for the production of a pre-cooked, high moisture, shelf-stable or refrigerated acidified filled pasta having a filling within a dough skin which includes mixing pasta ingredients together to form a pasta dough, sheeting the dough to a sheet to form the skin of the filled pasta, encasing a filling having a water activity of from 0.93 to 0.97 and a pH of from 4.6 to 5.6 within the dough sheet to give a raw filled pasta, cooking the raw filled pasta in acidified water to a pH of 4.6 to 5.6 and a moisture content of from 45% to 65% by weight and a water activity of 0.94 to 0.995, and finally packaging the cooked pasta either with heat processing or under modified atmospheric conditions.
Patent DE-69831990-T2 (DE)
Inventor: HIRAI HIROYUKI
IPC: G03C7/12
Filed: 1998-03-18
Granted: 2006-05-24
Abstract: An electroluminescence device comprising a transparent substrate having thereon at least:     a color filter layer;   a transparent electrode; at least one organic compound layer including a light-emitting layer; and   a back electrode, in this order, wherein said color filter layer has red, green and blue pixel patterns formed by a process which comprises:   applying a coating solution of a silver halide photographic layer onto said transparent substrate to form a photographic material; patternwise exposing said silver halide color photographic material to light; and then subjecting the exposed silver halide color photographic material to color development.     <IMAGE>
Patent DE-69903842-T2 (DE)
Inventor: KOMOROWSKI S
IPC: F16H7/12
Filed: 1999-09-15
Granted: 2003-09-18
Abstract: A belt tensioner for tensioning a belt for a motor vehicle comprises a pivot shaft, a pivoting structure mounted for pivotal movement on the pivot shaft, and a pulley mounted for rotation on the pivoting structure. A spring biases the pivoting structure in a direction that moves the pulley mounted on the pivoting structure into tensioning engagement with the belt. A bolt is constructed and arranged to mount the belt tensioner on the motor vehicle engine mount. The bolt is constructed and arranged to be tightened to a predetermined extent for installing the tensioner of the motor vehicle, the predetermined extent is the same extent to which the bolt is tightened during normal operation of the tensioner. A clamping structure applies a predetermined clamping force on the pivot shaft after the bolt is tightened to the predetermined extent. The predetermined clamping force is sufficiently large to maintain the pivot shaft in perpendicular relation to the engine mount and prevent tilting of the pivot shaft when the tensioner is moved into installed tensioning engagement with the belt, yet sufficiently small to permit manual movement of the pivot shaft relative to the mounting bolt for adjusting the amount of tension applied by the tensioner to the belt.
Patent DE-69925585-T2 (DE)
Inventor: CHATFIELD NEVILLE
IPC: C12N1/21
Filed: 1999-03-25
Granted: 2006-07-13
Abstract: The invention provides a bacterium attenuated by a non-reverting mutation in each of the aroC gene, the ompF gene and the ompC gene. The bacterium is useful as a vaccine. The bacterium may, for example, be an attenuated strain of E. coli useful in vaccination against diarrhoea.
Patent HU-E034161-T2 (HU)
Title: Solid forms containing meloxicam with improved buccal taste and process for their preparation
Inventor: STROPPOLO FEDERICO
IPC: A61K9/20
Filed: 2007-06-11
Abstract: A solid dosage form of meloxicam containing an acid and sugars or polyalcohols or a mixture thereof.
Patent TR-200000384-T2 (TR)
Inventor: REESE COLIN BERNARD
IPC: C07F9/165
Filed: 1998-08-10
Abstract: A process for the synthesis in solution phase of a phosphorothioate triester is provided. The process comprises the solution phase coupling of an H-phosphonate with an alcohol in the presence of a coupling agent to form an H-phosphonate diester. The H-phosphonate diester is oxidised in situ with a sulfur transfer agent to produce the phosphorothioate triester. Preferably, the H-phosphonate and alcohol are protected nucleosides or oligonucleotides. Oligonucleotide H-phosphonates which can be used in the formation of phosphorothioate triesters are also provided.
Patent TR-200001005-T2 (TR)
Title: Hidrofobik olarak değiştirilmiş poli (asetal veya ketal-polieter), poliüretan ve poliakrilatın girdaplı polimer süspansiyonu.
Inventor: BURDICK CHARLES LEE
IPC: C09D7/00
Filed: 1998-10-15
Abstract: Suda çözünebilen hidrofobik olarak degistirilmis poliüretanlar, poliakrilatlar ve poli(asetal-veya ketal-polieterler) ve karbon ihtiva eden tuzlar, çökertme islemi ve bunlarin sulu sistemlerde yogunlastirici olarak kullanilmasi.
Patent TR-200001009-T2 (TR)
Title: İnsan vücudunun dengesini yenileyen bir aparat.
Inventor: BARDON ALAIN
IPC: A63B22/18
Filed: 1998-10-13
Abstract: Bu bulus, insan vücudunun dengesinin yenilenmesine iliskin ve ana eleman olarak tedavi edilmekte olan hastayi desteklemek için salinim hareketi ile çalisan bir platformdan (2) olusmaktadir. Bahsedilen platform, bir motor elemanla çalismaktadir ve salinim hareketini ve geri dönüsümlü dönme hareketini bir merkez destek noktasi (6) etrafindan almaktadir. Bahsedilen salinim ve dönme hareketinin genligi, hizi ve bunlarin degistirilmesi aparatin kullanimi esnasinda saglanabilmektedir.
Patent TR-200001841-T2 (TR)
Title: Gazlarda azot protoksit tenörünün düşürülmesi için katalizör.
Inventor: NEVEU BERNARD
IPC: C01B39/44
Filed: 1998-12-16
Abstract: Bu bulus nisbeten düsük temperatürlerde çalisan, gazlardaki azot protoksit tenörünün düsürülmesine yönelik bir katalizör ile ilgili olup, burada katalizörün aktivitesi su buharinin mevcudiyetine karsi pek de duyarli degildir ve hidrotermik degradasyona karsi iyi bir mukavemet arzeder ve katalizör demir ile esanji yapilan ferrieritten hazirlanir. Bu bulus düsük bir N2O  muhtevasina sahip olan gazlarin (örnegin, nitrik asit üreten tesislerde nesredilen ve de nitrik asit kullanilarak organik bilesiklerin oksitlenmesi esnasinda nesredilen yüksek N2O muhtevali gazlarin) muamele edilmesinde faydalidir.
Patent TR-200002402-T2 (TR)
Title: Aspartil proteaz inhibitörü ön-ilaçlar.
Inventor: HALE MICHAEL R
IPC: A61K31/496
Filed: 1998-12-23
Abstract: Bu bulus, aspartil proteaz inhibitörleri olan sülfonamidler sinifindan ön-ilaçlarla ilgilidir. Bu bulus bir sikkinda, HIV aspartil proteaz inhibitörleri olan, ve su içinde uygun çözünürlüge, agizdan yüksek biyolojik temin edilebilirlige sahip olmalari ve aktif bilesenin canli ortamda kolaylikla açiga çikarilabilmesi ile tanimlanan yeni bir ön-ilaç sinifi ile ilgilidir. Bu bulus ayrica, bu ön-ilaçlari ihtiva eden farmasötik terkiplerle ilgilidir. Bu bulusa ait ön-ilaçlar ve farmasötik terkipler, hap yükünü azaltmak ve hastanin tedavi programina riayet etmesini artirmak için çok uygundurlar. Bu bulus ayrica memelileri bu ön-ilaçlar ve farmasötik terkiplerle tedavi etmeye yönelik yöntemlerle de ilgilidir.
Patent TR-200003713-T2 (TR)
Title: Homosistein ve C-reaktif proteinin seviyelerinin düşürülmesi.
Inventor: ANDERSON PAMELA WANG
IPC: A61P9/10
Filed: 1999-06-04
Abstract: Söz konusu bulus ihtiyaci olan bir memeliye  homosistein ve/veya C-reaktif protein seviyelerini düsürmek maksadiyla, etkili olacak miktarda formül (I)'e uygun bir terkibin ya da  farmasötik tuzunun ya da solvatinin verilmesinden mürekkep bir yöntem ile ilgilidir.
Patent TR-200101021-T2 (TR)
Inventor: ASMUSSEN BODO
IPC: A61K31/325
Filed: 1999-01-08
Abstract: Pharmaceutical composition comprising (S)-N-ethyl-3-[1-dimethylamino)ethyl]-N-methyl-phenyl-carbamate in free base or acid addition salt form and an anti-oxidant. Said pharmaceutical compositions may be delivered to a patient using a transdermal delivery device.
Patent TR-200103331-T2 (TR)
Title: Tepkime kabında birikmenin engellenmesi
Inventor: CHADWICK PAUL
IPC: B01J19/00
Filed: 2000-05-15
Abstract: Sülfanasyon tepkime karisimina maruz kalan yüzeyleri, yüzeyde manganez dioksit olusturulan bir tabaka içeren bir manganez kaynagi ihtiva eden bir akiskan ile ön muamele edilmis olan bir sülfa(na)syon tepkime kabinada, kirletici materyalin birikmesinin engellenmesi için bir yöntemdir
Patent TR-200200007-T2 (TR)
Inventor: NAHMIASNANNI MARCO
IPC: B60C9/18
Filed: 2000-07-04
Abstract: A high performance tire includes a carcass provided with at least one carcass ply, a belt including two or more layers of reinforcing cords parallel to each other in a layer and crossed with respect to those of an adjacent layer, applied circumferentially on the carcass, a radially-external layer of circumferentially-oriented reinforcing cords applied on the belt, and a tread band comprising an underlayer and an external layer. The underlayer may have a hardness which is substantially constant over a temperature range between 23° C. and 100° C. The underlayer may also have an elastic modulus which is substantially constant over a temperature range between 70° C. and 100° C. Additionally, the underlayer may be made from an elastomer compound comprising reinforcing fibers and hardening resins. Further, the underlayer may have a hardness and an elastic modulus which remain substantially constant between 70° C. and 100° C. A method for making the tire is also disclosed.
Patent DE-602004000386-T2 (DE)
Inventor: CAPORUSSO ALESSANDRO
IPC: F15B11/048
Filed: 2004-02-25
Granted: 2006-11-02
Abstract: A hydraulic circuit for linearly driving a machine-tool slider in both directions, comprising an hydraulic cylinder (5) whose piston rod (4) is connected to a slider and which is fed with pressurized fluid from a reservoir (14) by a pump (15) through a three-position four-way valve (18), a check valve (12-13), and between the last ones, a pair of throttling valves (19, 19') which are mounted symmetrically each other and operated to generate an increased pressure in either one or the other chamber, which is at the moment in a low pressure, of the hydraulic cylinder (5) in order to slow down said slider in its work motion in both directions of linear travelling when a programmable interval is approached from a predetermined position for each working pass. Situated in the bypass (190, 190') of each throttling valve (19, 19'), among the same valves (19, 19') and the hydraulic cylinder (5), is a manual flow control valve (20, 20'). <IMAGE>
Patent DE-602004000415-T2 (DE)
Inventor: LORENZO JUAN A
IPC: A61M25/12
Filed: 2004-06-04
Granted: 2006-11-23
Abstract: A balloon catheter stent delivery system (10) for treating a patient comprising a catheter shaft (14) extending from a catheter proximal end to a catheter distal end and defining a longitudinal axis. A substantially inelastic balloon (12) is affixed to the catheter shaft near its distal end, the balloon having a central inflatable portion between a proximal collar and a distal collar each of which is affixed to the catheter shaft. In an initial configuration, the balloon is deflated, pleated and wrapped around the catheter shaft. A stent (34) is crimped around the inflatable portion of the deflated balloon in the initial configuration. A distal tip is defined by a portion of the catheter extending distally of a point where the distal collar of the balloon meets the catheter shaft; the distal tip having a length along the longitudinal axis of 2.5 millimeters or less. The distal tip defines more than one cam surface which tapers in the distal direction. A first of the cam surfaces defines an angle of 5-20 degrees with respect to the longitudinal axis, located within 0.254 millimeters of the catheter distal end. A second of the cam surfaces defines an angle of 18-35 degrees with respect to the longitudinal axis, located within 2.0 millimeters of the catheter distal end. This allows the cam surfaces to gently urge the balloon catheter to more smoothly follow the desired path during advancement to a desired site for treatment.A method of making such a balloon catheter stent delivery system is also disclosed.