baber/WOPTO huggingface dataset:
Patent DK-2357230-T3 (DK)
Inventor: KREITER SEBASTIAN
IPC: C12N15/67
Filed: 2006-09-28
Granted: 2014-06-02
Abstract: Nucleic acid molecule comprising (in 5'-3' transcription direction) (a) a promoter; (b) a transcriptable nucleic acid sequence or a nucleic acid sequence for inserting in to a transcriptable nucleic acid sequence; (c1) a first nucleic acid sequence, which corresponds to the 3'-non-translated region of a gene or is derived from it; and (c2) a second nucleic acid sequence, which corresponds to the 3'-non-translated region of a gene or is derived from it, is new. Independent claims are included for: (1) a nucleic acid molecule comprising (in 5'-3' transcription direction) (a) a promoter; (b) a transcriptable nucleic acid sequence or a nucleic acid sequence for inserting in to a transcriptable nucleic acid sequence; and (c) a nucleic acid sequence with a transcription under control of (a), where the nucleic acid sequence codes for a nucleotide sequence of at least 20 sequentially arranged A-nucleotide in the transcript; (2) a nucleic acid molecule obtained after linearization; (3) a RNA obtained by transcription, preferably in vitro transcription, with the nucleic acid molecule under control of (a); (4) a method for in vitro transcription of a selected RNA molecule, in order to increase its stability and/or translation efficiency, comprising coupling of a first nucleic acid sequence (b1), which corresponds to the 3'- non translated region of a gene or is derived from it, at the 3'-end of the nucleic acid sequence (a), which is transcriptable into RNA molecule; coupling of a second nucleic acid sequence (b2), which corresponds to the 3'-non-translated region of a gene or is derived from it, at the 3'-end the first nucleic acid sequence (b1), and in vitro transcription of obtained nucleic acid; (5) a method for the translation of a selected RNA molecule, in order to increase the expression, comprising coupling of the first nucleic acid sequence (b1); coupling of the second nucleic acid sequence (b2), and translating the mRNA that is obtained through transcription of the obtained nucleic acid; (6) an in vitro transcription of a selected RNA molecule, in order to increase its stability and/or translation efficiency, comprising coupling of a nucleic acid sequence (b), which codes for a nucleotide sequence of at least 20 sequentially arranged A-nucleotides, at the 3'-end of a nucleic acid sequence (a), which is transcriptable in to RNA molecule, and in vitro transcription of the obtained nucleic acid; (7) a method for the translation of a selected mRNA molecule, in order to increase its expression, comprising coupling of a nucleic acid sequence, which codes for a nucleotide sequence of at least 20 sequential A-nucleotides, at the 3'-end of the nucleic acid sequence (a), and translating mRNA, which is available by transcription of the obtained nucleic acid; and (8) a RNA obtained by the in vitro transcription of a selected RNA molecule.
Patent DK-2709613-T3 (DK)
Inventor: OLDACH DAVID W
IPC: A61P31/14
Filed: 2012-09-14
Granted: 2018-02-26
Abstract: This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.
Patent DK-2841456-T3 (DK)
Inventor: ANDERSEN METTE DAHL
IPC: C07K16/28
Filed: 2013-04-25
Granted: 2018-08-13
Abstract: Provided are compositions and methods relating to human CD30L antigen binding proteins. Compositions described herein include: human CD30L antigen binding proteins, polynucleotides encoding human CD30L antigen binding proteins, vectors comprising these polynucleotides, host cells, and pharmaceutical compositions. Methods of making and using each of these compositions are also provided.
Patent DK-0405298-T3 (DK)
Inventor: BINDER DIETER DR
IPC: A61K31/45
Filed: 1990-06-19
Granted: 1994-06-06
Abstract: Thienopyran derivatives of the general formula   <IMAGE> I  in which the radial  <IMAGE>  denotes one of the formulae  <IMAGE>  R denotes hydrogen or a radical -CN, -CHO, -CH=NOH, -CONH2 or -COOR1, R1 denotes the radical (C1-C4)-alkyl and n denotes an integer 3, 4 or 5, and a process for their preparation, pharmaceutical preparation and their use for the treatment of diseases which can be cured by activation of membrane K+ channels, such as high blood pressure and asthma.
Patent DK-0413289-T3 (DK)
Inventor: DIANA GUY DOMINIC
IPC: C07D271/06
Filed: 1990-08-13
Granted: 1995-03-27
Abstract: Compounds of the formulas <CHEM>  wherein:  Y is an alkylene bridge of 3-9 carbon atoms;  R min  is lower-alkyl or hydroxy-lower-alkyl of 1-5 carbon atoms; R1 and R2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and R8 is hydrogen or lower-alkyl of 1-5 carbon atoms, with the proviso that when R8 is hydrogen R min  is hydroxy-lower-alkyl, are useful as antiviral agents, particularly against picornaviruses, including numerous strains of rhinovirus.
Patent DK-0427634-T3 (DK)
Inventor: DUMAS JEAN-LOUIS
IPC: A44C5/20
Filed: 1990-11-08
Granted: 1994-04-05
Abstract: This fastener comprises two elements (3, 4) connected to the band (1), the first element (3) including a pin (9) adapted to be fitted into retaining bearing surfaces (12) defined by hooks (13) on the second element (4), and a clasp (11) associated with the pin (9) and capable of being swung over and locked onto the second element (4). The second element (4) is provided with a safety hook (16) pivotally mounted on a transverse pin (10) of the second element and capable of being clipped onto the pin (9) of the first element (3) before the clasp (11) is swung over onto the second element (4). The fastener may be easily adjusted with one hand and does not require the provision of adjustment orifices on the band and hides the free end portion of the band, this end portion of the band being indeed interposed between the surface of the object surrounded by the band and the end portion (1a) of the band carrying the first element (3).
Patent DK-0458823-T3 (DK)
Inventor: GANDOLFI CARMELO A
IPC: C07D413/00
Filed: 1990-02-15
Granted: 1994-02-21
Abstract: A process for the optical resolution of racemic 1,4-dihydropyridines, containing isothioureido groups. Salification of racemic isothioureas with optically active acids produces diasteroisomeric mixtures of isothiouronium salts, that, using conventional techniques, are separated in the individual components to give optically pure isothioureides of 1,4-dihydropyridines and salts thereof with conventional acids. Said optically pure 1,4-dihydropyridines can then be subjected to desulphuration and to different transformations to give other enantiomerically pure and therapeutically useful 1,4-dihydropyridines.
Patent DK-0463286-T3 (DK)
Inventor: BRANDAUER OTTO
IPC: B29C31/06
Filed: 1991-01-23
Granted: 1994-11-21
Abstract: A central control and computer system 7 is used for the charging of processing machines 6. It allows any number of processing machines 6 to be charged from any number of material containers 1 (silos) via a common blower 5. Each individual feeding station 4 is flexibly fastened to a load cell 8. The data determined at the load cell 8 are alternately switched to a single control and computer system 7 in multiplex mode. <IMAGE>
Patent DK-0446776-T3 (DK)
Inventor: SCHNEIDER WILFRIED
IPC: E06B3/62
Filed: 1991-03-06
Granted: 1994-11-07
Abstract: A sealing profile, in particular for sealing between a window frame and the associated window pane, comprises a compound profile cross-section with different wall thicknesses, the sealing profile in the longitudinal direction having one or more through-cavities. To ensure reliable and permanent sealing against moisture and heat loss, at least one cavity of the sealing profile is filled with a filler material. Furthermore, the wall of the filled cavity facing the area to be sealed is made thin in relation to the other wall thicknesses. After the window pane has been fitted, the cavity thus tears open and the filler material can emerge for sealing purposes. In the method for producing such a sealing profile by extruding, at least one cavity is formed before the sealing profile emerges from the die and then, directly after the cavity has been formed, filler material is introduced into the cavity in the emergence region. <IMAGE>
Patent DK-0452873-T3 (DK)
Inventor: KURODA TAKESHI
IPC: A61K31/4427
Filed: 1991-04-16
Granted: 1996-07-29
Abstract: Disclosed are naphthyridine derivatives represented by formula (I)   <CHEM>  wherein: X represents hydrogen; lower alkyl; aralkyl; substituted or unsubstituted aryl; substituted or unsubstituted aromatic heterocyclic group; -NR<1>R<2> wherein R<1> and R<2> independently represent hydrogen or lower alkyl; <CHEM> wherein W represents N or CH, Z represents a single bond, oxygen or NR<3> (wherein R<3> represents hydrogen, lower alkyl or benzyl) and n1 and n2 represent an integer of 1 to 3; or substituted or unsubstituted thiazolinyl; and     Y is a single bond or alkylene and pharmaceutically acceptable salts thereof. The compounds show potent anti-inflammatory activity and are expected to be useful in treating rheumarthritis.
Patent DK-0488338-T3 (DK)
Inventor: KOMATSU AKIRA
IPC: H04R1/00
Filed: 1991-11-29
Granted: 1995-10-02
Abstract: The invention relates to a body-felt sound unit having a vibration transmitting member (2) imbedded in a human body support member (8), for example, a chair, a bed, etc., and an electro-mechanical vibration transducer (4) attached to the vibration transmitting member (2), the transducer (4) generating mechanical vibration on receipt of a low-frequency current, thereby transmitting the vibration to the human body (9). The vibration transmitting member (2) comprises a flat plate- or net-shaped member (3) of a relatively large area, and the electro-mechanical vibration transducer (4) is attached to the vibration transmitting member (2) such that the direction of vibration generated from the transducer (4) coincides with the direction of the width of the vibration transmitting member (2) so as to transmit transverse vibration to the vibration transmitting member (2). Even if the vibration transmitting member (2) is thin, the apparent rigidity becomes high, so that the transmission of vibration is effectively made. <IMAGE>
Patent DK-0488497-T3 (DK)
Inventor: YOSHINO AKIRA
IPC: C23C2/02
Filed: 1991-08-06
Granted: 1996-03-04
Abstract: To form a plating coat on steel works, the works are held in a fluorine- or fluoride-containing gas atmosphere in a heated condition to thereby remove oxidized scales such as SiOx, MnOx and the like on the surface layer of the work and form a fluoride layer to prevent forming oxidized scale newly. The fluoride layer is easily eliminated by the action of flux added to a plating bath or by holding the fluorinated steel works in an atmosphere containing hydrogen prior to dipping in the plating bath to activate the steel surface. The activated steel surface is improved in compatability with the plating bath and the like to realize a good quality plating coat formation.
Patent DK-0466612-T3 (DK)
Inventor: PEPIN REGIS
IPC: A01N37/18
Filed: 1991-06-11
Granted: 1994-12-27
Abstract: The present invention relates to a process for the control of fungal disease of plants by applying to the leaves of the plants: a) 2-(4-chlorobenzylidene)-5,5-diemthyl-1-(1H-1,2,4-triazol-1-ylmethyl)-1-cyclopentanol; b) one or more fungicides suitable for protecting against the said fungal diseases and to compositions which may be used in the process.
Patent DK-0458940-T3 (DK)
Inventor: PARMENTIER MARC
IPC: C07K14/72
Filed: 1990-12-12
Granted: 1996-11-11
Abstract: The invention concerns a polypeptide possessing thyrotropin receptor activity,  characterised in that it comprises the amino-acid sequence shown in fig 11, or a fragment thereof, or an amino-acid sequence derived from this sequence by substitution or deletion of any of the amino-acid residues indicated in fig 11, or by insertion of additional amino-acid residues.
Patent DK-0499920-T3 (DK)
Inventor: GAVIRAGHI GIOVANNI
IPC: A61K31/455
Filed: 1992-02-08
Granted: 1998-01-26
Abstract: The use of (E) -4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6 -dimethyl-3,5-pyridinedicarboyxlic acid diethyl ester (lacidipine) for the treatment and/or prevention of arteriosclerosis.
Patent DK-0514749-T3 (DK)
Inventor: HEIMANN BRUNO
IPC: B05B15/06
Filed: 1992-05-13
Granted: 1995-09-18
Abstract: To improve a hand shower having at least one shower jet generating device and a handle on which a releasable connection for a hose conduit for feeding in the water is provided, it is proposed that a quick acting coupling for a plug connection of the hose conduit be provided in the handle, at least one transverse locking bow for the coupling of the plug connection being arranged in the handle in a manner which allows the said bow to be displaced to a limited extent radially. 
<IMAGE>
Patent DK-0522435-T3 (DK)
Inventor: LAUFS FRITZ DR
IPC: B41N3/08
Filed: 1992-07-01
Granted: 1995-07-24
Abstract: The invention relates to a fountain concentrate (damping concentrate) which essentially contains 
 
  a) 1-15% by weight of buffer substances, 
  b) 2-20% by weight of an additive which comprises one or more of the substances water-soluble polysaccharides, polyglycols and polyhydric alcohols, 
  c) 2-10% by weight of preservatives, 
  d) 0.01-5% by weight of nonionic, low-foam surfactant, comprising one or more of the substances tertiary acetylene glycol, ethylene oxide surfactant, propylene oxide surfactant, fatty alcohol ethoxylates, fatty acid ethoxylates and siloxane alkoxylates, 
  e) 1-35% by weight of a compound of the formula
 C4H9-O[-CH2-CH2-O]n-H
 where n is an integer from 1 to 10, or a mixture of these compounds, 
  f) 0.1-10% by weight of 2-ethyl-1,3-hexanediol and 
  g) 25-90% by weight of water.
Patent DK-0511867-T3 (DK)
Inventor: DABORA REBECCA L
IPC: A61P9/00
Filed: 1992-04-30
Granted: 1996-09-09
Abstract: A process is disclosed, for the formation of simvastatin, which comprises the sequential acylation of a diol lactone to form a bis acylated intermediate followed by selective deacylation and lactone ring closure to form simvastatin.
Patent DK-0533433-T3 (DK)
Inventor: CAUFIELD CRAIG EUGENE
IPC: A61K38/13
Filed: 1992-09-15
Granted: 1997-05-12
Abstract: Use of rapamycin (I) opt. in combination with cyclosporin A for mfr. of a medicament for treating immunoinflammatory skin or bowel diseases in mammals is new. Pref. the medicament is adapted for oral, parenteral, intranasal, intrabronchial, topical, transdermal or rectal admin. The medicament is in unit dosage form, each unit contg. 0.001-100 pref. 0.1-50 esp. 0.3-25 mg/kg (I).
Patent DK-0519903-T3 (DK)
Inventor: EIBL JOHANN DR
IPC: A61K45/06
Filed: 1992-06-16
Granted: 2003-01-27
Abstract: The invention relates to a drug which can be administered parenterally and has a thrombolytic effect and contains activated protein C which is free of thrombin activity and contains no antibodies against protein C or activated protein C, which drug is characterised in that it is free of serum amyloid P and of infectious agents. The drug according to the invention is very suitable for dissolving venous thrombi and has no side effects, such as fall in fibrinogen or bleeding.
Patent DK-0589924-T3 (DK)
Inventor: LOWE JOHN ADAMS III
IPC: C07D215/42
Filed: 1992-05-05
Granted: 1996-09-30
Abstract: PCT No. PCT/US92/03571 Sec. 371 Date Dec. 14, 1993 Sec. 102(e) Date Dec. 14, 1993 PCT Filed May 5, 1992 PCT Pub. No. WO92/06079 PCT Pub. Date Apr. 16, 1992The present invention relates to novel fluoroalkoxybenzylamino derivatives of nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula    <IMAGE>  I  wherein Q, X1, x2 and X3 are as defined below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders.
Patent DK-0560730-T3 (DK)
Inventor: KOTTIRSCH GEORG
IPC: C07D309/30
Filed: 1993-03-08
Granted: 1996-10-28
Abstract: Pseudopeptides of formula I in free or salt form <CHEM> wherein A, B, R1, X, Y and m are defined as in claim 1, and their use in the prophylactic and acute treatment of thrombosis.
Patent DK-0672043-T3 (DK)
Inventor: VANDENBERK JAN
IPC: A61P43/00
Filed: 1993-07-06
Granted: 2001-08-27
Abstract: The invention is concerned with novel compounds of the formulathe pharmaceutically acceptable acid addition salts thereof and the stereochemically isomeric forms thereof, whereinX is oxygen or sulphur; R1 is hydrogen or halo; R2 is hydrogen, C1-4alkyl, phenylmethyl or halophenylmethyl; Alk is C1-4alkanediyl; -Z-A- is a bivalent radical selected from the group consisting of -S-CH2-CH2, -S-CH2-CH2-CH2-, -S-CH=CH-, -CH=CH-CH=CH-, -C(=CHR3)-CH2-CH2-CH2-, -CH=CH-O-, -CHR4-CH2-CH2-, -CHR4-CH2-CH2-CH2-, -CHR4-CH2-CH2-CH2-CH2-; in said bivalent radicals one hydrogen may be replaced by C1-4alkyl; R3 is phenyl or halophenyl; each R4 independently represents hydrogen, hydroxy, phenylmethyl or halophenylmethyl. Pharmaceutical compositions of said compounds and use as a medicine.
Patent DK-0670892-T3 (DK)
Inventor: SASISEKHARAN RAMNATH
IPC: C12N9/88
Filed: 1993-11-30
Granted: 2005-08-15
Abstract: A single, reproducible scheme to simultaneously purify all three of the heparin lyases from F. heparinum to apparent homogeneity is disclosed herein. The kinetic properties of the heparin lyases have been determined as well as the conditions to optimize their activity and stability. Mono-clonal antibodies to the three heparinases are also described and are useful for detection, isolation and characterization of the heparinases.
Patent DK-0654968-T3 (DK)
Inventor: DE FAIRE JOHAN
IPC: A01N63/10
Filed: 1993-08-17
Granted: 1999-07-19
Abstract: PCT No. PCT/SE93/00684 Sec. 371 Date Feb. 10, 1995 Sec. 102(e) Date Feb. 10, 1995 PCT Filed Aug. 17, 1993 PCT Pub. No. WO94/04033 PCT Pub. Date Mar. 3, 1994The present invention relates to an anti-microbial composition for non-pharmaceutical cleaning of contaminated materials, bodies and surfaces, especially contaminated liquids and gases. The composition comprises at least one anti-microbially active protein which has been isolated from mussels, preferably together with glycogen. A quick test for qualitative testing of possibly contaminated liquids, especially drinking water, is also disclosed. The quick test comprises a test tube containing a predetermined amount of the anti-microbial composition. A predetermined amount of the liquid is added to the test tube, shaken and allowed to sediment. The quality of the liquid is determined by a quality indicator extending along the tube.
Patent DK-0732579-T3 (DK)
Inventor: BONGARDT WOLFGANG
IPC: G01B11/30
Filed: 1995-08-18
Granted: 2002-04-29
Abstract: The sheet of glass to be examined (1) is placed horizontally in a support frame (2) and is illuminated uniformly with white light from a source (4). The light falling on the glass plate is reflected on to a screen (6). The image appearing on this screen is captured by one or several colour video cameras (12-15). For each primary colour, and for each point on the image the luminance is determined, and the relative colour reaction for each colour is calculated by dividing the luminance value for one colour by the sum of the luminance values for that point. These relative colour fractions are then compared with predetermined reference values.
Patent DK-0720269-T3 (DK)
Inventor: PLUMER LOUIS
IPC: H02P23/24
Filed: 1995-09-29
Granted: 1998-09-21
Abstract: The control unit (14) is designed to stop operation of the motor (2) when an overload exceeds a set value. The unit (14) includes a device (8) for measuring phase shift between one of several parameters: voltage or current (U1,U2,I2,I3) of the principal phase (1) and/or the auxiliary phase (2) and another of these parameters. The unit (14) interrupts the supply to the motor (2) when the measured delay time is less than a set value contained in memory (13).
Patent DK-0746580-T3 (DK)
Inventor: KLUTH HERMANN
IPC: B65D83/14
Filed: 1995-02-16
Granted: 1999-05-25
Abstract: A composition useful for the production of foam plastics from disposable pressurized containers is provided. The composition comprises at least one polyisocyanate or isocyanate prepolymer, at least one catalyst for the reaction of the isocyanate group with the OH group, at least one blowing agent and at least one foam stabilizer. One day at the latest after application from said disposable pressurized container, the residue of said composition left in the pressurized container has a diisocyanate monomer content of less than 5.0% by weight, based on the residual contents of the emptied container.
Patent DK-0773759-T3 (DK)
Inventor: BAERVELDT GEORGE
IPC: A61M27/00
Filed: 1995-08-01
Granted: 2000-05-22
Abstract: An implant for use in the treatment of glaucoma is disclosed wherein the implant comprises an elastomeric plate having a non-valved elastomeric drainage tube attached thereto. The plate is curved so as to conform to the spherical anatomy of the eyeball. An annular sloped wall extends from the plate and surrounds the opening of the drainage tube into the plate. The plate is inserted beneath Tenon's capsule and sutured to the sclera utilizing temporary and non-dissolving permanent sutures. The annular wall provides a temporary sealing surface against the sclera. The drainage tube is tunnelled through the sclera and cornea and inserted into the anterior chamber, thus providing fluid communication between the anterior chamber and the elastomeric plate. The annular wall around the tube forms a temporary seal which restricts the drainage of aqueous fluid until formation of the bleb is completed. After bleb formation occurs, the temporary sutures around the wall are removed or dissolve. Once the temporary sutures are gone, the portion of the plate that is not stitched to the sclera floats within the bleb and breaks the seal between the implant and the sclera. Once the seal is broken, unrestricted flow between the anterior chamber and bleb is maintained.
Patent DK-0784719-T3 (DK)
Inventor: JANNACH HELMUT
IPC: D06F58/02
Filed: 1995-10-04
Granted: 2000-04-03
Abstract: PCT No. PCT/AT95/00192 Sec. 371 Date Jun. 30, 1997 Sec. 102(e) Date Jun. 30, 1997 PCT Filed Oct. 4, 1995 PCT Pub. No. WO96/10670 PCT Pub. Date Apr. 11, 1996The invention relates to a device for drying protective suits, for which the suit is put over a supporting framework, which consists of tubes and reaches into all extremities of the suit, the tubes having outlet openings at their ends for warm air that has been blown in. The supporting framework 1; 101 is formed by tubular hoops 2, 3, 4, 5; 102, 103, 104, 105; 102', 103', 104', 105' which, in the area of the feet and hands of the protective suit, have bends 6, 7, 8, 9; 106, 107, 108, 109; 106', 107', 108', 109', in which the outlet openings 21; 121 for the drying air are disposed. An additional connecting piece 124; 124', which optionally can be shut off, is provided at the common manifold 18, 118, 118' for supplying detergents and disinfectants, it being possible preferably to shut off the drying air line before the connecting piece 124 also by means of a valve 125.
Patent DK-0846577-T3 (DK)
Inventor: RODEWALD HELMUT
IPC: B60C11/12
Filed: 1997-11-27
Granted: 2002-02-04
Abstract: The tread has incisions both in the shoulders (A, C) and central region (B). The improvement is that in the shoulder regions the incisions are thinner than in the central region.
Patent DK-0820877-T3 (DK)
Inventor: TAZAKI HIROSHI
IPC: G09F9/37
Filed: 1997-07-22
Granted: 2001-08-13
Abstract: A magnetic migration display panel comprising a dispersion liquid layer composed of a magnetic particle, a dispersion medium composed of an organic solvent, a thickening agent composed of fatty acid his-amide with a hydroxyl group having a melting point of 120 DEG C to 160 DEG C, and if desired a coloring material, on a substrate.