baber/WOPTO huggingface dataset:
Patent WO-2018190239-A1 (WO)
Title: ポンプ装置
Inventor: KOKUBO NOBUKI
IPC: F04D29/041
Filed: 2018-04-05
Abstract: モータによりインペラを駆動して流体を流通させたときに、インペラがポンプ室を区画するケース体の側に引き寄せられることを抑制できるポンプ装置を提供すること。インペラ（７）はケース体（５）とモータ（３）の端壁部（４）により区画されたポンプ室（６）に配置される。インペラ（７）はシュラウド（１２２）からモータ（３）の端壁部（４）の側に突出する裏羽根（１２５）を有する。インペラ（７）が駆動されてポンプ室（６）を流体が流通すると、裏羽根（１２５）は、インペラ（７）とモータ（３）の端壁部（４）との間から流体（Ｗ３）を掻き出す。これにより、インペラ（７）とモータ（３）の端壁部（４）との間に負圧（Ｆ２）が発生するので、この負圧（Ｆ２）によって、インペラ（７）がモータ（３）の端壁部（４）の側に引き寄せられる。裏羽根（１２５）は当該インペラ（７）を端壁部（４）の側に吸引する吸引力（負圧（Ｆ２））を発生させる吸引力発生機構（１４０）として機能する。
Patent WO-2019193741-A1 (WO)
Inventor: KANAZAWA Seigo
IPC: G06T11/60
Filed: 2018-04-06
Abstract: La présente invention a pour objet de fournir une technologie permettant de corriger, autant que possible, une ligne discontinue ayant des intervalles espacés de manière irrégulière en une ligne discontinue ayant des intervalles espacés de manière régulière, même sans modifier une séquence de points. À cet effet, une unité d'acquisition (11) acquiert sélectivement des parties de ligne continue (23), comprenant chacune un segment de ligne (24) reliant au moins deux points parmi une pluralité de points (21) compris dans une séquence de points, et des parties vides (27), comprenant chacune un espace vide entre au moins deux points parmi la pluralité de points (21). Sur la base de plis dans les segments de ligne (24) et/ou de plis dans des segments de ligne virtuelle (28), une unité de correction (12) corrige la longueur des parties de ligne continue (23) et/ou des parties vides (27).
Patent WO-2018216399-A1 (WO)
Inventor: ADACHI HIDETO
IPC: G07G1/01
Filed: 2018-04-16
Abstract: La présente invention concerne un système de gestion d'historique d'achats comprenant un serveur de gestion d'historique d'achats et un dispositif terminal d'informations. Le serveur de gestion d'historique d'achats stocke des données d'historique d'achats d'un produit acheté dans un magasin par un consommateur, en association avec des premières informations d'identification de produit. Le dispositif de terminal d'informations stocke des secondes informations d'identification de produit. Les premières informations d'identification de produit peuvent être associées de manière unique aux secondes informations d'identification de produit. Les données d'historique d'achats sont des informations n'identifiant pas un consommateur, ce qui fait en sorte que des consommateurs individuels ne peuvent pas être personnellement identifiés.
Patent WO-2019021557-A1 (WO)
Title: Laminated body and flexible device provided with said laminated body
Inventor: NISHIO NAOTAKA
IPC: B32B17/10
Filed: 2018-04-25
Abstract: Provided is a laminated body comprising a thinned glass plate and a resin film which are bonded together by means of an adhesive and having excellent bending resistance. A laminated body according to the present invention has a configuration in which a glass plate having a thickness of 150 μm or less and a resin film are laminated together via an adhesive layer, and has a bending resistance of 10 or more according to the following test. Bending resistance test: A set of operation comprises bending the laminated body by 180° from a stretched state so as to have a bending radius of 3 mm in a direction in which a surface of the glass plate becomes concave, and then stretching the laminated body again. The operation is performed at the rate of 43 sets per minute, and the number of the sets when a crack has occurred in the laminated body is regarded as an index of the bending resistance.
Patent WO-2019207687-A1 (WO)
Inventor: HIRATA KAZUNORI
IPC: B25J9/06
Filed: 2018-04-25
Abstract: L'invention concerne un robot articulé horizontal pourvu : d'une base (20) ; d'un bras comprenant une pluralité d'éléments de bras ; et d'une main (1) agencée de manière à être décalée par rapport à la pointe du bras (200) dans un premier plan parallèle à un plan dans lequel fonctionne le bras (200), ladite main (1) étant conçue pour tourner autour d'un axe de rotation positionné dans le premier plan.
Patent WO-2018207744-A1 (WO)
Inventor: KAMIMURA MITSUHIRO
IPC: A61K38/08
Filed: 2018-05-07
Abstract: L'invention concerne un support de transport  in vivo , ledit support de transport  in vivo  transportant dans le corps une substance amphotère chargée négativement, qui comprend un gel de silice. Le complexe de la présente invention comprend une substance amphotère chargée négativement et un support de transport  in vivo  capable d'adsorber/ de désorber la substance amphotère, le support de transport  in vivo  comprenant un gel de silice.
Patent WO-2019003689-A1 (WO)
Title: Projection indication device, baggage sorting system, and projection indication method
Inventor: MORIYAMA TAKAAKI
IPC: H04N5/74
Filed: 2018-05-16
Abstract: A projection indication device that generates a projection image to project on baggage on the basis of the result of reading baggage specification information included in a label attached to the baggage, wherein: the projection indication device comprises a processor and a memory; and the processor, in cooperation with the memory, detects the occurrence of an error, generates a projection image indicating the occurrence of the error when the occurrence of an error is detected, and indicates the projection of the projection image on the baggage for which the error occurred.
Patent WO-2018225519-A1 (WO)
Title: 溶接条件設定装置及び溶接条件設定方法
Inventor: SATO KAZUTAKA
IPC: B25J13/02
Filed: 2018-05-24
Abstract: 溶接ロボットシステムにおける溶接動作の各種条件を設定するための溶接条件設定装置であって、溶接ロボットの駆動を制御するため溶接ロボットに接続された制御装置と、作業者に対し情報を表示すると共に、制御装置へ指示等を入力するため制御装置に接続された教示操作盤とを有し、教示操作盤に、溶接の種類の特徴を表現した図柄からなる溶接記号を表示し、作業者が、溶接記号により溶接の種類を選択し指定する。
Patent WO-2018235555-A1 (WO)
Title: Service plug
Inventor: YAMADA GO
IPC: H01R13/629
Filed: 2018-05-30
Abstract: Provided is a service plug that is equipped with a first connector housing, a second connector housing (20), and a lever (30), wherein when the lever (30) is at a first operation position, the lever (30) has, at a terminal end (E) of a cam groove (34), a stopping wall (38) that prevents a cam pin within the cam groove (34) from falling in a direction in which the second connector housing (20) makes a transition from an engagement state to a disengagement state.
Patent WO-2019239455-A1 (WO)
Title: Endoscope light source device, endoscope light source system, and endoscope
Inventor: KAMEE HIROYUKI
IPC: A61B1/07
Filed: 2018-06-11
Abstract: An endoscope light source device 1 is provided with: an optical fiber 70 that guides a part of emitted light emitted from a light source 20 and entering from a fiber end surface 70SA; a ferrule 31 that has a ferrule end surface 31SA having an opening of a through hole H31 having the optical fiber 70 inserted therein, that includes a scattering body for scattering, in the inside thereof, the other part of the emitted light entering the ferrule end surface 31SA, and that emits scattered light caused by scattering from a side surface 31SS; and an optical sensor 40 that is disposed around the side surface 31SS of the ferrule 31 and that receives the scattered light.
Patent WO-2019009106-A1 (WO)
Title: Actuator, valve, fluid supply system, and semiconductor production device
Inventor: MIURA TAKERU
IPC: F15B15/14
Filed: 2018-06-22
Abstract: Provided are an actuator, a valve, a fluid supply system, and a semiconductor production device that make it possible for variations in an opening/closing speed to be reduced by means of a simple configuration. A valve (1) that comprises: a body (10) that has fluid passages (11b, 11c) formed therein; a diaphragm (15) that opens/closes the fluid passages; a stem (26) that can move toward and away from the diaphragm (15) to make the diaphragm (15) open/close the fluid passages (11b, 11c); a pressure-reducing valve (40) that is provided inside a casing and reduces the pressure of a drive fluid that is supplied from the outside to a prescribed pressure; and a drive part (30) that is provided inside the casing and uses drive fluid that the pressure-reducing valve (40) has reduced to the prescribed pressure to drive the stem (26).
Patent WO-2019009131-A1 (WO)
Title: Retractable auxiliary step for vehicle decorated with aerodynamic parts
Inventor: NAKAZATO TOMOKI
IPC: B62D37/02
Filed: 2018-06-26
Abstract: [Problem] The objective of the present invention is to decorate a front surface of an auxiliary step with an aerodynamic part to integrate the auxiliary step with the aerodynamic part, thereby improving the appearance and achieving differentiation. [Solution] A vehicle in which aerodynamic parts are attached to a vehicle body lower portion of the vehicle is provided with an auxiliary step which eliminates a height difference when boarding and alighting, by causing a running board to project outward from a retracted position, in which the auxiliary step is retained in an existing vehicle step lower portion of a boarding and alighting opening of the vehicle, toward a forward lower portion, which is a boarding and alighting side of a vehicle step, in conjunction with opening and closing of a door, characterized in that a front surface of the auxiliary step serves as a portion of the aerodynamic parts.
Patent WO-2020008565-A1 (WO)
Inventor: NISHIO NAOKI
IPC: H01M4/36
Filed: 2018-07-04
Abstract: Selon un mode de réalisation, l'invention concerne une électrode positive. L'électrode positive comprend une couche contenant un matériau actif d'électrode positive, le matériau actif d'électrode positive comprenant un oxyde composite de lithium-manganèse et un oxyde de lithium-cobalt. La couche contenant un matériau actif d'électrode positive comporte une surface dans laquelle une pluralité de pics d'énergie de liaison d'Al, dans le spectre de spectroscopie photoélectronique à rayons X, sont compris dans la plage de 70-78 eV. La couche contenant un matériau actif d'électrode positive satisfait la formule relationnelle 0<H/(G+H)≤0,1. Dans la formule, G représente le pourcentage en poids de l'oxyde composite de lithium-manganèse dans le matériau actif d'électrode positive ; H représente le pourcentage en poids de l'oxyde de lithium-cobalt dans le matériau actif d'électrode positive.
Patent WO-2020021700-A1 (WO)
Title: Refrigeration cycle device
Inventor: NISHIYAMA TAKUMI
IPC: F25B6/02
Filed: 2018-07-27
Abstract: This refrigeration cycle device (100) uses a non-azeotropic refrigerant mixture. The refrigeration cycle device (100) is provided with a compressor (1), a first heat exchanger (3), a pressure reducing device (4), a second heat exchanger (5a), a third heat exchanger (5b), and a blower device (7). The blower device (7) delivers air to the second heat exchanger (5a) and the third heat exchanger (5b). The non-azeotropic refrigerant mixture circulates in a first circulation direction through the compressor (1), the first heat exchanger (3), the pressure reducing device (4), the second heat exchanger (5a), and the third heat exchanger (5b). The flow resistance of the second heat exchanger (5a) is higher than the flow resistance of the third heat exchanger (5b). The blower device (7) forms a flow parallel to the flow of the non-azeotropic refrigerant mixture flowing through the second heat exchanger (5a) and the third heat exchanger (5b).
Patent WO-2019054075-A1 (WO)
Title: Abnormal portion detection system
Inventor: SATO YASUSHI
IPC: G06T7/00
Filed: 2018-08-02
Abstract: The present invention specifies, clearly and in detail, the place of an element that has an abnormal portion in a large-scale facility such as a photovoltaic power station or a bridge. Provided is an abnormal portion detection system 10 having an imaging device 500 and a user terminal 300. The imaging device 500 is provided with: an imaging unit 550 that captures an image of a facility; and a transmission unit 512 that transmits the image to the user terminal 300. The user terminal 300 is provided with: a reception unit 312 that receives the image from the imaging device 500; a storage unit 320 that stores a drawing which is a drawing of the facility and which has pieces of information indicating the places of elements constituting the facility; an abnormal portion detection unit 314 that detects an abnormal portion of each element on the basis of the image; a composition unit 315 that generates a composite image in which the drawing and the image are superimposed on each other such that the contour of each element illustrated in the drawing and the contour of the element in the image are associated with each other; and an abnormal portion output unit 316 that, on the basis of the composite image, outputs place information of the element the abnormal portion of which has been detected, to a display device 330.
Patent WO-2020031371-A1 (WO)
Title: Imaging device, accessory, and camera system having imaging device and accessory
Inventor: UEDA HARUHISA
IPC: H04N5/225
Filed: 2018-08-10
Abstract: This imaging device is characterized in that: said imaging device has a first mount part and a first cylindrical member configured in a color differing from that of the first mount part, the first cylindrical member being arranged in the circumferential direction of the first mount part; an accessory has an external portion, a second mount part, and a second cylindrical member configured in a color that differs from that of the second mount part and is of a similar color to that of the first cylindrical member, the second cylindrical member being arranged in the circumferential direction of the second mount part; contact is made between the first mount part and the second mount part when the accessory is mounted on the imaging device; and the first and second cylindrical members are exposed to the outside regardless of whether the accessory is attached to or detached from the imaging device.
Patent WO-2019082499-A1 (WO)
Title: Gasket
Inventor: FURUBAYASHI JUN
IPC: F16J15/10
Filed: 2018-08-27
Abstract: A gasket (100) is provided with: an outer peripheral-side seal part (10) having an outer peripheral-side base section (11), a first lip section (12), and a second lip section (13); an inner peripheral-side seal part (20) having an inner peripheral- side base section (21), a third lip section (22), and a fourth lip section (23); and a connection part (30). The height (H1) of the outer peripheral-side seal part (10) and the height (H2) of the inner peripheral-side seal part (20) are mutually equal.
Patent WO-2019045090-A1 (WO)
Title: Method for producing influenza ha split vaccine
Inventor: TAKAHASHI YOSHIMASA
IPC: C07K14/11
Filed: 2018-09-03
Abstract: Provided is a method for producing an influenza HA split vaccine that produces antibodies that bind to the HA stem region of influenza, which is less likely to undergo antigenic mutation. Acid treatment of the influenza HA split vaccine is performed. An influenza HA split vaccine that produces antibodies that bind to LAH of the HA stem region is obtained by performing acid treatment. This influenza HA split vaccine has excellent protective ability against influenza virus infections of different antigenicity.
Patent WO-2019054474-A1 (WO)
Title: Alkaline earth metal titanate crystal laminate
Inventor: TACHIKAWA TAKASHI
IPC: H01G4/12
Filed: 2018-09-14
Abstract: Provided are a new type of crystal laminate of an alkaline earth metal titanate having improved catalytic activity, and a method for the production thereof.　This crystal laminate comprises alkaline earth metal titanate crystals as constituent units and is characterised in that the crystals serving as constituent units are cubic, tetragonal or orthorhombic, have a primary particle size of no more than 500nm, and are layered with an orientation in the direction of the {100} planes of said crystals.
Patent WO-2020065755-A1 (WO)
Title: 表示装置、マルチモニタシステム、映像信号伝送方法、表示方法
Inventor: DOI YUTA
IPC: H04N5/66
Filed: 2018-09-26
Abstract: 入力される映像信号に対して信号処理を行う映像信号処理部（６００）と、前記映像信号処理部の機能が正常であるか否かを検出する故障検出部（６１０）と、前記故障検出部の検出結果に基づいて、前記映像信号処理部の機能が正常である場合に、前記映像信号処理部によって信号処理された後の映像信号を、前記後段の表示装置に出力し、前記映像信号処理部の機能が正常ではない場合に、前記映像信号処理部に入力される映像信号を、自表示装置にデイジーチェーン接続された後段の表示装置に出力する信号スイッチ部（６２０）と、を有する。
Patent WO-2019082597-A1 (WO)
Title: Clutch device
Inventor: KOBAYASHI YUKI
IPC: F16D43/20
Filed: 2018-09-28
Abstract: Provided is a clutch device with which different desired torque values can be set without allowing an assist torque and a slipper torque to influence each other. This clutch device 100 is provided with a center clutch 105 and a pressure clutch 111 that hold a clutch plate 104 which is disposed facing a friction plate 103 which is rotationally driven by a driving shaft. The center clutch 105 is provided with a center-side assist cam surface 106a and a center-side slipper cam surface 106b. The pressure clutch 111 is provided with a pressure-side assist cam surface 112a and a pressure-side slipper cam surface 112b. The positions in radial directions of the contact surfaces of the center-side assist cam surface 106a and the pressure-side assist cam surface 112a and the contact surfaces of the center-side slipper cam surface 106b and the pressure-side slipper cam surface 112b, are formed in mutually different positions.
Patent WO-2019073830-A1 (WO)
Title: Positive electrode composition for lithium ion secondary batteries, positive electrode for lithium ion secondary batteries, and lithium ion secondary battery
Inventor: OSUMI SHINICHIRO
IPC: H01M4/62
Filed: 2018-09-28
Abstract: The present invention provides a positive electrode composition for lithium ion secondary batteries, which enables easy achievement of a lithium ion secondary battery that has a low internal resistance, while exhibiting excellent output characteristics, cycle characteristics and low-temperature characteristics. A positive electrode composition for lithium ion secondary batteries, which contains a conductive agent and an active material that is capable of absorbing and desorbing lithium ions, and which is characterized in that: the active material is composed of a lithium nickel cobalt manganese composite oxide; the conductive agent is composed of a carbon black and carbon nanotubes; the carbon black has a BET specific surface area of 100-400 m2/g and a DBP absorption of 210-380 ml/100 g; and the carbon nanotubes have an average diameter of 7-15 nm.
Patent WO-2019087783-A1 (WO)
Inventor: NISHINO TATSUKI
IPC: H04N5/369
Filed: 2018-10-17
Abstract: 本技術は、ＳＰＡＤを用いて測距を行う場合の測距精度を向上させることができるようにする撮像装置及び撮像システムに関する。 撮像装置は、ＳＰＡＤ（単一光子アバランシェフォトダイオード）と、前記ＳＰＡＤに直列に接続されている抵抗成分と、前記ＳＰＡＤへの光子の入射を示す受光信号を出力する出力部と、前記受光信号の出力に同期してパルス信号を出力するパルス生成部とをそれぞれ有する画素部が配置されている画素アレイ部を備え、前記画素部は、前記ＳＰＡＤと前記抵抗成分との間に接続され、前記パルス信号に同期してオフするスイッチと、前記パルス信号に同期して、前記抵抗成分を介して前記ＳＰＡＤに流れる入力電流を引き込むことにより、前記ＳＰＡＤへの前記入力電流の流れを抑制する引き込み部とのうち少なくとも１つを有する。本技術は、例えば、距離画像を撮影するカメラに適用できる。
Patent WO-2019078264-A1 (WO)
Title: Actuator
Inventor: HOKUTO Daisuke
IPC: F16H57/029
Filed: 2018-10-17
Abstract: An actuator (10) comprises: a first housing part (41); a second housing part (42) that forms a storage space (44) together with the first housing part (41); and fastening members (43) that fasten the first housing part (41) and the second housing part (42). The first housing part (41) has: a sealing surface (62) that is in contact with the second housing part (42); fastening sections (63) into which the fastening members (43) are screwed; and ribs (74). The fastening sections (63) are formed so as to protrude outward when viewed in a direction perpendicular to the sealing surface (62). The ribs (74) are within a range enveloping the first housing part (41) when viewed in a direction perpendicular to the sealing surface (62) and are positioned at locations adjacent to the fastening sections (63). The ribs (74) are formed on the side opposite the second housing part (42) with respect to the sealing surface (62), and have, on the sealing surface (62) side, a parallel surface (75) with respect to the sealing surface (62).
Patent WO-2019078327-A1 (WO)
Title: Inflammation evaluation system, evaluation method, program, and non-transient recording medium
Inventor: OKUYA TERUHISA
IPC: A61B5/107
Filed: 2018-10-19
Abstract: A problem to be addressed by the present disclosure is to mitigate decreases in evaluation precision. An evaluation system (6) comprises an acquisition part (60) for acquiring a measurement value measured by a measurement device (7) on a skin measurement site (51), the measurement value including an erythema value and an intensity value (melanin value) for a color different from that of the erythema. The evaluation system (6) according to a first aspect comprises an evaluation part (61) for evaluating an inflammation on the basis of the erythema value included in a plurality of measurement values acquired with the acquisition part (60). The evaluation part (61) selects, from among the plurality of measurement values, a measurement value having an intensity value (melanin value) within a prescribed range as an evaluation-candidate measurement value. The evaluation part (61) evaluates the inflammation on the basis of the erythema value included in the evaluation-candidate measurement value.
Patent WO-2019078351-A1 (WO)
Title: Led illumination device
Inventor: OKUMURA MASAHIRO
IPC: B60Q3/82
Filed: 2018-10-19
Abstract: A substrate (23) is fixed to the rear surface side of an inside frame (5). An LED light source (17a) is mounted approximately at the center of the rear surface of the substrate (23). A light emitting surface of the LED light source (17a) is inserted into a through-hole (25a) of a light reflection plate (21a). An outer reflection frame (19) is positioned on the rear surface side of an outside frame (3). Using the inside frame (5) as a reference, the substrate (23) on which the LED light source (17a) is mounted and the light reflection plate (21a) are positioned on the outer reflection frame (19) side (the rear surface side of the inside frame (5)). Furthermore, using the inside frame (5) as a reference, a lens (10), or an inner lens (7) and an outer lens (9), form a convex-shaped part on the side opposite to the outer reflection frame (19) (the front surface side of the inside frame (5)). The convex-shaped part formed by the lens (10), or by the inner lens (7) and the outer lens (9), is a light extraction part which extracts light from the first LED light source.
Patent WO-2019082996-A1 (WO)
Title: Sealing agent for organic electroluminescent display elements
Inventor: SASAKI MAKIKO
IPC: H05B33/04
Filed: 2018-10-25
Abstract: A sealing agent for organic electroluminescent display elements, which contains (A) an acyclic alkanediol di(meth)acrylate having 6 or more carbon atoms, (B) a cyclic monomer and (C) a photopolymerization initiator, and wherein the cyclic monomer (B) contains a cyclic monofunctional (meth)acrylate and a cyclic bifunctional (meth)acrylate, while satisfying the following formula (I) and formula (III). (I): 8 mPa·s ≤ η ≤ 50 mPa·s (III): γ/2η < 0.9 m/s (In the formulae, η represents the viscosity as measured at 25°C with use of an E-type viscometer; and γ represents the static surface tension as measured by a pendant drop method.)
Patent WO-2019102832-A1 (WO)
Inventor: SAKOH RYUSUKE
IPC: C09D171/02
Filed: 2018-11-05
Abstract: 撥水撥油性、耐摩耗性に優れた硬化被膜を形成できるフルオロポリエーテル基含有ポリマー、及び該ポリマー及び／又はその部分（加水分解）縮合物を含む表面処理剤、並びに該処理剤で表面処理された物品を提供する。　下式のフルオロポリエーテル基含有ポリマー。 Ｒｆ1－［Ｎ（Ｖ）β（Ｅ）γ］α　（１） Ｒｆ1－［Ｑ－（Ｇ）δ－（Ｅ'）ε－Ｂ］α　（２） （Ｒｆ1は１価又は２価のフルオロオキシアルキレン基含有ポリマー残基、Ｎは３～８価の有機基、Ｖは水酸基又は加水分解性基含有１価の基、Ｅはオキシアルキレン基と水酸基又は加水分解性基とを有する１価の基、αは１又は２、β、γは１～６、β＋γは２～７。Ｑは単結合又は２価有機基、Ｇは水酸基又は加水分解性基含有２価の基、Ｅ'はオキシアルキレン基と水酸基又は加水分解性基とを有する２価の基。ＢはＨ、アルキル基又はハロゲン原子、δは１～１０、εは１～１０。）
Patent WO-2019093468-A1 (WO)
Title: 間葉系幹細胞からインスリン産生細胞を製造する方法、インスリン産生細胞、細胞構造体および医薬組成物
Inventor: NAKAMURA KENTARO
IPC: C12N5/071
Filed: 2018-11-09
Abstract: 本発明の課題は、間葉系幹細胞から、十分なグルコース応答性を有するインスリン産生細胞を製造する方法、十分なグルコース応答性を有するインスリン産生細胞、上記インスリン産生細胞を含む細胞構造体、および医薬組成物を提供することである。本発明によれば、（ａ）複数個の生体親和性高分子ブロックと、複数個の間葉系幹細胞とをインキュベートすることによって細胞構造体を製造する工程、（ｂ）工程（ａ）においてインキュベートする前の間葉系幹細胞、工程（ａ）においてインキュベートしている間葉系幹細胞、または工程（ａ）で製造した細胞構造体のいずれか一以上を、ＧＬＰ－１受容体作動薬を含む培地中で培養する工程、および（ｃ）工程（ａ）または工程（ｂ）で得られた細胞構造体を、水溶性ビタミンおよび肝細胞増殖因子を含む培地中で培養する工程を含む、間葉系幹細胞からインスリン産生細胞を製造する方法が提供される。