baber/WOPTO huggingface dataset:
Patent CA-3128271-A1 (CA)
Inventor: GUAN ZHICHAO
IPC: G01N33/543
Filed: 2020-01-03
Abstract: L'invention concerne un procédé de détection quantitative d'une unique molécule et un système de détection associé, qui peuvent être utilisés pour détecter quantitativement un niveau moléculaire unique de protéines, de petites molécules et de molécules d'acides nucléiques. Le procédé de détection et le système de détection marquent une molécule à détecter en utilisant des nanoparticules renforcées par des signaux in situ et dotées de propriétés optiques par des technologies de modification chimique et de reconnaissance de molécules, de telle sorte que le signal d'une seule molécule peut être capturé et reconnu par un dispositif d'imagerie optique. Une détection quantitative à ultra-haute sensibilité de la molécule à détecter est réalisée par collecte de statistiques sur le nombre de signaux associés aux nanoparticules renforcées par des signaux in situ.
Patent CA-3128356-A1 (CA)
Title: Internet of things label for factory and warehouse applications
Inventor: WILLIAMS JOHN DALTON
IPC: H05K1/02
Filed: 2021-08-16
Abstract: Systems, apparatuses and methods may provide for label technology that includes a flexible substrate and a flexible circuit coupled to the flexible substrate, the flexible circuit including a power source, a microcontroller, a plurality of sensors, one or more transceivers, and an antenna. The microcontroller may be configured to identify sensor readings in one or more signals from the plurality of sensors and send the sensor readings to one or more of a central computer or a computer network via one or more standard wireless transmission protocols, wherein at least one of the sensor readings is sent in a push communication.
Patent CA-3129865-A1 (CA)
Title: Constitutively active chimeric cytokine receptors
Inventor: LIN REGINA JUNHUI
IPC: C07K14/435
Filed: 2020-02-28
Abstract: Provided herein are constitutively active chimeric cytokine receptors (CACCRs). When present on chimeric antigen receptor (CAR)-bearing immune cells, such CACCRs allow for increased immune cell activation, proliferation, persistence, and/or potency. Also provided are methods of making and using the CACCRs described herein.
Patent CA-3130236-A1 (CA)
Inventor: MARIKAR MOHAMMED
IPC: G06F16/901
Filed: 2021-09-09
Abstract: Embodiments generally relate to real-time profile search interfaces and web services with the ability to real-time search for and view details on entities and visualizations of the network. The computer service enables real-time profile search of entities and performs a sequence of data aggregation heuristics to present a consolidated view of an individual.
Patent CA-3131428-A1 (CA)
Inventor: CURRAN JERALD WAYNE
IPC: A61M25/10
Filed: 2020-03-27
Abstract: Methods and systems for using mechanical circulatory support concurrently with a biologic therapy (e.g. a gene therapy vector). Particular adaptations include a cardiac therapy method in which a blood vessel such as a coronary artery or blood vessel is occluded, followed by injecting a gene therapy vector or biologic distal to the occlusion site and waiting a certain amount of time, while using the mechanical circulatory support system to provide circulatory support to the patient.
Patent CA-3131734-A1 (CA)
Inventor: REID TERENCE K
IPC: B01D61/16
Filed: 2020-02-24
Abstract: La présente invention concerne des systèmes et des procédés pour augmenter l'élimination de substances perfluoroalkylées et d'autres contaminants composés organiques récalcitrants de l'eau, et en particulier l'eau souterraine et potable, à l'aide de charbon actif en poudre submicronique.
Patent CA-3143231-A1 (CA)
Inventor: MARCHAND BENOIT
IPC: G06F15/16
Filed: 2020-06-05
Abstract: Un système donné à titre d'exemple, un procédé et un support accessible par ordinateur pour attribuer une pluralité de tâches à une pluralité de nuds informatiques peuvent comprendre, par exemple, la réception de premières informations relatives aux nuds informatiques, les premières informations pouvant comprendre un certain nombre de curs dans chacun des nuds de calcul, la génération de secondes informations en séparant le nombre de curs dans chacun des nuds de calcul, et l'attribution des tâches aux nuds de calcul sur la base des secondes informations. Les premières informations peuvent en outre comprendre (i) une distance d'une connexion réseau entre chacun des nuds informatiques, et (ii) une bande passante de la connexion réseau. Les secondes informations peuvent être générées sur la base des tâches. Les secondes informations peuvent être générées sur la base d'un certain nombre de dimensions des tâches. Les tâches peuvent être attribuées sur la base d'une minimisation d'un nombre de communications entre les nuds.
Patent CA-3143555-A1 (CA)
Title: Peptides and uses thereof
Inventor: GEARING ANDREW
IPC: A61P25/04
Filed: 2020-07-08
Abstract: Disclosed herein are methods and compositions for treating or preventing neuropathic pain in a subject, the method comprising administering to a subject a therapeutically effective amount of prolactin, or a functional variant thereof, wherein the functional variant comprises a peptide of formula (I) or a pharmaceutically acceptable salt thereof: R1 -C-R-I-X1 -X2-X3-X4-N-C-R2 (I) (SEQ ID NO:1, excluding R1) wherein X1 is an amino acid residue selected from isoleucine (I) and valine (V); X2 is an amino acid residue selected from histidine (H) and tyrosine (Y); X3 is an amino acid residue selected from aspartic acid (D) and asparagine (N); X4 is an amino acid residue selected from asparagine (N) and serine (S); R1 is selected from the group consisting of YLKLLK (SEQ ID NO: 31 ), LKLLK (SEQ ID N0:32), KLLK (SEQ ID N0:33), LLK, LL, K or R1 is absent; and R2 is G (glycine), or R2 is absent.
Patent CA-3145984-A1 (CA)
Inventor: SNIDER GEORGE E
IPC: C10G31/06
Filed: 2022-01-18
Abstract: The invention generally relates to a modular crude oil refinery (MCOR). The MCOR is designed for smaller scale deployment with a capacity to process in the range of 3,000-4,000 barrels of crude oil per day in a single production unit and with the potential to scale to over 100,000 barrels per day with linked production units. More specifically, a MCOR includes a low temperature, low pressure primary separation reactor, condensing system and recirculation systems operating in a closed loop configuration that enable the production of both heavy and light hydrocarbon products with substantially no emissions. The MCOR has the capability to receive and process crude-oil feedstocks of varying API gravity and be controlled to produce a variety of both heavy and light products including cleaner-burning bunker fuels, jet fuels, diesel fuels, gasoline fuels and asphalt binders.
Patent CA-3147036-A1 (CA)
Title: Systeme d'investigation
Inventor: VANDERLAND WILLIAM SIDNEY
IPC: G06Q10/02
Filed: 2020-07-10
Abstract: L'invention concerne un procédé qui consiste à : recevoir des données de billet et de facture ; comparer les données de billet et de facture à des règles afin d'identifier des anomalies ; générer une interface utilisateur graphique affichant des informations relatives aux anomalies et des options sélectionnables pour attribuer les anomalies à des comptes d'utilisateur ; en réponse à la réception d'une sélection d'option pour attribuer une anomalie particulière à un compte d'utilisateur, stocker des données attribuant l'anomalie particulière au compte d'utilisateur ; en réponse à la réception d'une demande d'accès au compte d'utilisateur, générer une interface utilisateur graphique affichant des informations relatives à l'anomalie particulière.
Patent CA-3148519-A1 (CA)
Inventor: ORTIZ GARCIA JUAN P
IPC: A61B17/04
Filed: 2020-10-15
Abstract: A filament cutting device includes an outer sheath. A bushing is coupled to a distal end of the outer sheath and defining a first radial cavity extending radially inwardly through a wall of the bushing and configured to capture a portion of a filament. An actuation wire is slidably extendable within the outer sheath and bushing and an engaging body comprising a second radial cavity defined along a length of the engaging body is coupled to a distal end of the actuation wire. Relative axial movement of the bushing and engaging body cause the filament to be severed. This is illustrative of a disclosed embodiment, and other embodiments are also disclosed.
Patent CA-3150061-A1 (CA)
Inventor: BENENATO KERRY
IPC: A61K47/24
Filed: 2020-08-06
Abstract: La présente invention concerne des compositions de nanoparticules lipidiques (ou LNP de l'anglais « lipid nanoparticle ») de l'administration de cellules cibles qui permettent une administration améliorée d'agents, par ex., des acides nucléiques, tels que des ARN thérapeutiques et/ou prophylactiques, des cellules cibles, en particulier des cellules hépatiques et/ou spléniques. Les LNP comprennent une quantité efficace d'un lipide de potentialisation de l'administration de cellules cibles de telle sorte que l'administration d'un agent par une LNP d'administration de cellules cibles est améliorée par comparaison avec une LNP manquant d'agent de potentialisation de l'administration de cellules cibles. L'invention concerne également des procédés d'utilisation des LNP d'administration de cellules cibles destinés à l'administration d'agents, par ex., l'administration d'acides nucléiques, destinés à l'expression protéique et destinés à moduler l'activité des cellules cibles.
Patent CA-3150925-A1 (CA)
Title: Method and system for analysing biomechanical activity and exposure to a biomechanical risk factor on a human subject in a context of physical activity
Inventor: PROJETTI MAXIME
IPC: A61B5/11
Filed: 2020-08-13
Abstract: The invention relates to a method for analysing the biomechanical activity of a human subject and the exposure to a biomechanical risk factor in a context of physical activity, which comprises collecting signals from sensors of one or more muscles of the subject, collecting signals representing the movement of the subject, and processing these signals to extract signals representative of the vibratory behaviour of the muscle or muscles of the subject. This method also comprises detecting a drift of the vibratory signals in relation to a frame of reference of the vibratory behaviour of said muscle or muscles in the context of physical activity, and predicting a physiological break time necessary for the subject's muscles to recover their reference vibratory behaviour.
Patent CA-3151630-A1 (CA)
Title: A method for controlling a vibrating prilling bucket in a urea prilling process
Inventor: MARRONE LEONARDO
IPC: B01J2/02
Filed: 2020-09-01
Abstract: A method for controlling a prilling bucket in the prilling of a a urea melt (UM) including: feeding the urea melt to a prilling bucket (1) which vibrates under the action of a magnetostrictive device (2), wherein the vibration of the bucket is controlled, as a function of the amount of urea melt to be prilled, by the following steps: acquisition of a time-varying input signal (3) which represents the flow rate of urea melt fed to the prilling bucket; generation of a first signal (5) and of a second signal (6), independently from each other, as a function of said input signal (3); generation of a third signal (10) having a frequency which is modulated by said first signal and an magnitude which is modulated by said second signal, and use of said third signal to drive said magnetostrictive device (2).
Patent CA-3151991-A1 (CA)
Inventor: VENNERI PAOLO FRANCESCO
IPC: G21C1/12
Filed: 2020-10-04
Abstract: An enhanced architecture for a nuclear reactor core includes several technologies: (1) nuclear fuel tiles (S-Block); and (2) a high-temperature thermal insulator and tube liners with a low-temperature solid-phase moderator (U-Mod) to improve safety, reliability, heat transfer, efficiency, and compactness. In S-Block, nuclear fuel tiles include a fuel shape designed with an interlocking geometry pattern to optimize heat transfer between nuclear fuel tiles and into a fuel coolant and bring the fuel coolant in direct contact with the nuclear fuel tiles. Nuclear fuel tiles can be shaped with discontinuous nuclear fuel lateral facets and have fuel coolant passages formed therein to provide direct contact between the fuel coolant and the nuclear fuel tiles. In U-Mod, tube liners with low hydrogen diffusivity retain hydrogen in the low-temperature solid- phase moderator even at elevated temperatures and the high-temperature thermal insulator insulates the solid-phase moderator from the nuclear fuel tiles.
Patent CA-3153493-A1 (CA)
Inventor: WELLS RICHARD
IPC: A61B5/11
Filed: 2017-11-03
Abstract: Linvention concerne des systèmes et des procédés d'affichage de mouvements cliniques de réalité augmentée qui peuvent utiliser un dispositif de réalité augmentée pour afficher des aspects d'un mouvement clinique. Les systèmes et les procédés peuvent utiliser un dispositif de capture de mouvement pour capturer le mouvement clinique. Le procédé peut comprendre l'analyse d'informations concernant le mouvement clinique pour déterminer un trajet de mouvement tridimensionnel représentant au moins une partie du mouvement clinique, et mettre à jour automatiquement une région de trajet de mouvement tridimensionnel et une cible virtuelle en réponse à un mouvement dun utilisateur. La région de trajet de mouvement tridimensionnel et la cible virtuelle sont affichées dans lenvironnement de réalité augmentée relativement à lobjet physique dans lenvironnement réel.
Patent CA-3155545-A1 (CA)
Title: Process for the purification of hyaluronic acid sodium salt, conducted in organic solvent
Inventor: STUCCHI LUCA
IPC: C08B37/00
Filed: 2020-10-19
Abstract: The present invention relates to a process for the preparation of pharmaceutical, injectable or ophthalmic grade hyaluronic acid, or a salt thereof, for use in the dermocosmetic or pharmaceutical field or in medical devices, which comprises dissolution of hyaluronic acid or a salt thereof in organic solvent, a heat cycle, and recovery of the product by precipitation and successive washes in organic solvents.
Patent CA-3157584-A1 (CA)
Inventor: FREASIER JAMES
IPC: A61L29/06
Filed: 2020-11-11
Abstract: A catheter configured to release nitric oxide and chlorhexidine providing anti-platelet and antimicrobial properties is manufactured by impregnating a thermoplastic polyurethane catheter extrusion with a nitric oxide releasing compound and with chlorhexidine. Thereafter, the impregnated catheter extrusion is coated with a polyurethane coating comprising chlorhexidine and/or a nitric oxide releasing compound. In the impregnating step, the catheter extrusion may be exposed to a solvent having the nitric oxide releasing compound and chlorhexidine dissolved therein. The solvent is removed from the catheter extrusion. In the coating step, the impregnated catheter extrusion may be dip coated in a polymer solution comprising polyurethane and chlorhexidine and/or a nitric oxide releasing compound in a suitable solvent. The nitric oxide releasing compound, impregnated and/or coated, may be selected from s-nitroso-n-acetylpenicillamine (SNAP), s-nitrosoglutathione (GSNO), and mixtures thereof. The chlorhexidine, impregnated and/or coated, may be selected from chlorhexidine diacetate, chlorhexidine base, chlorhexidine gluconate, and mixtures thereof.
Patent CA-3158754-A1 (CA)
Title: Introducteur pour instrument electrochirurgical
Inventor: HANCOCK CHRISTOPHER PAUL
IPC: A61B18/14
Filed: 2020-09-02
Abstract: Divers modes de réalisation concernent un introducteur pour introduire un instrument électrochirurgical dans un corps d'un patient. L'introducteur comprend : un élément tubulaire définissant une lumière à travers laquelle l'instrument électrochirurgical peut être inséré ; et un ensemble de refroidissement configuré pour éliminer la chaleur de l'élément tubulaire. D'autres modes de réalisation concernent un système électrochirurgical comprenant un instrument électrochirurgical et un introducteur.
Patent CA-3159776-A1 (CA)
Title: Dispositif de surveillance personnel portable et procedes associes
Inventor: STINSON SEAN
IPC: G01N21/00
Filed: 2017-10-03
Abstract: La technologie de linvention concerne un dispositif de surveillance personnel portable et des procédés associés. Cette technologie permet en particulier daméliorer la capacité de systèmes de dispositifs de surveillance personnels par lactivation de fonctions telles que des communications bidirectionnelles échangées au moyen du dispositif de surveillance personnel ; lassociation de menaces possibles avec un ou plusieurs emplacements ; et la détermination dynamique demplacements sécurisés et de trajets dévacuation potentiels Linvention concerne également des dispositifs de surveillance qui améliorent la détection de menaces ou de risques possibles en permettant lutilisation dune unité de base avec divers modules de capteur de remplacement.
Patent CA-3161218-A1 (CA)
Inventor: BOURASSA SHELDON
IPC: H04R25/00
Filed: 2022-06-01
Abstract: Abstract: I wear hearing aids and I had difficulty inserting them into my ears. Hard to see the side of my head and big fingers. I was losing interest in wearing them quickly as they were too hard to insert. I've tested several different diameters and strengths of small tubes to grab hold of the hearing aid and speaker wire of the hearing aid to push the hearing aid into my ears. The best tube is 3/16" diameter, soft enough not to hurt your ear, with a slot cut into the tube to hold the speaker wire. Tube is 1 1/2" long, the slot is %" cut down the length of the tube with a small "v" cut at the top of the slot to hold onto the speaker wire. A1/2" cap glued on at the opposite end of the tube with a silicone rubber adhesive to hold onto while inserting the hearing aid. Total length of the insertion tool assembled is 1 ~" long I put my hearing aids in and out twice a day. This tool works so well that I  do not hesitate to take the hearing aids in and out more than once a day. I now wear my hearing aids all the time. Claim or Claims: I am the sole inventor and claim exclusive privilege and property of this invention.  I designed it, constructed it and tested it. Date Recue/Date Received 2022-07-18
Patent CA-3165347-A1 (CA)
Inventor: ALONSO MICHAEL N
IPC: A61P37/06
Filed: 2021-01-21
Abstract: The invention relates to programmed death-ligand 1 (PD-L1) binding agents, nucleic acids comprising the inventive binding agents, vectors and cells comprising the inventive nucleic acids, and compositions thereof. The invention also relates to methods of producing the inventive binding agents, methods for treating a disease, disorder, or condition in a mammal, and methods for enhancing or reducing or inhibiting an immune response in a mammal.
Patent CA-3166906-A1 (CA)
Title: Manhole base liner and method for manufacturing a manhole base liner
Inventor: PREDL MANFRED
IPC: B29C63/02
Filed: 2017-12-06
Abstract: In aspect disclosed herein, the present disclosure provides a method for producing a formed part having a base body and at least one pipe connection opening, comprising:  creating a negative foun of the formed part; at least regionally wrapping the negative form with a flexible film, and creating the base body by molding a material in a liquid or pasty state on the negative form; wherein at least one transition strip and/or at least one pipe socket is arranged on the negative form and is molded to the base body.
Patent CA-3169281-A1 (CA)
Title: Special light effects system
Inventor: KRAUTHAMER AKIVA MEIR
IPC: A63F13/42
Filed: 2021-03-09
Abstract: A special effects system includes a retroreflective target, an object comprising one or more light sources disposed on an end of the object, where the end of the object is spatially oriented to face the retroreflective target such that light from the one or more light sources is emitted onto the retroreflective target, and a controller communicatively coupled to the one or more sensors and the one or more light sources, wherein the controller comprises a processor configured to adjust the light from the light source based in part on the on the one or more signals output by the one or more sensors, wherein the signals are indicative of a position of the object, or a condition of the one or more light sources.
Patent CA-3169668-A1 (CA)
Title: Systemes alimentes par batterie pour luminotherapie et procedes associes
Inventor: JOHNSON PATRICK LAMBERTH
IPC: A61N5/06
Filed: 2021-02-26
Abstract: L'invention concerne des systèmes de luminothérapie alimentés par batterie capables de délivrer 2 à 10 joules par cm2 de l'énergie lumineuse vers une zone de traitement cible couvrant plus de 700 cm2 de la surface du corps de telle sorte que la lumière pénètre à une profondeur de 2 à 8 mm au-dessous d'une surface de la peau de la zone de traitement cible.
Patent CA-3170829-A1 (CA)
Title: Treatment of cerebral palsy using fibroblasts
Inventor: ICHIM THOMAS
IPC: C12N5/00
Filed: 2021-02-12
Abstract: In some aspects, disclosed herein are methods and compositions for treatment or prevention of cerebral palsy using fibroblasts or derivatives thereof. Disclosed herein are fibroblasts and derivatives thereof capable of inducing neurogenesis and/or reducing inflammation in a subject. In some cases, the disclosed methods comprise use of conditioned fibroblasts. Fibroblasts may be conditioned with agents capable of enhancing therapeutic efficacy, for example oxytocin and/or human chorionic gonadotrophin (hCG).
Patent CA-3174925-A1 (CA)
Inventor: VIARD ANDREA
IPC: B32B5/26
Filed: 2021-03-11
Abstract: The invention relates to a reinforcing material (1) made of a unidirectional reinforcing layer (2) formed of one or more carbon reinforcing threads (3), combined with a layer of polymeric fibres (4, 5), on each of its faces, chosen from non-woven webs, the polymeric portion of the reinforcing material representing between 0.5 and 10% of the total weight of the reinforcing material (1), and preferably between 2 and 6% of its total weight, the unidirectional reinforcing layer (2) comprising one or more reinforcing threads (3) twisted individually according to a twist of 3 to 15 rpm, preferably 6 to 12 rpm.
Patent CA-3175594-A1 (CA)
Inventor: GREGORIS RAFFAELLA
IPC: B32B27/12
Filed: 2021-02-12
Abstract: The patch product comprises a membrane substrate suitable to be absorbed by the skin and based on natural polymers, as well as at least one active ingredient. It can be packaged in a wrapping comprising a support base, on which the patch product is placed, and a coating layer that acts as protection for the patch product.
Patent CA-3176171-A1 (CA)
Title: Systeme monte sur une barre de support et procede d'indication de proximite minimale pour vehicule de manege
Inventor: KISH SHAWN MICHAEL
IPC: B60R22/00
Filed: 2021-05-11
Abstract: Des aspects de la divulgation concernent un procédé, un appareil et un système pour retenir un passager dans un véhicule de manège. Le système comprend un siège de manège et un système de retenue conçu pour retenir le passager contre le siège de manège. Le système de retenue comprend une barre transversale destinée à être placée contre le passager, une barre de support ayant une première extrémité de barre de support accouplée à la barre transversale et une seconde extrémité de barre de support accouplée de façon rotative à un pivot monté sur une partie arrière supérieure du siège de manège et un rabat accouplé à la barre de support. Le rabat est conçu pour s'insérer dans, ou être extrait de, une fente formée à l'intérieur d'une structure latérale de siège lorsque la barre de support est mise en rotation autour du pivot et indiquer si la barre transversale a atteint une position fermée minimale pour retenir le passager sur la base d'une position d'un marquage sur le rabat par rapport à la fente.