baber/WOPTO huggingface dataset:
Patent AU-2015283850-A1 (AU)
Title: GLS1 inhibitors for treating disease
Inventor: CZAKO BARBARA
IPC: A61K31/4439
Filed: 2015-07-02
Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS I mediated diseases, such as cancer, having the structure of Formula I. Methods of inhibition GLS I activity in a human or animal subject are also provided. Accordingly, the inventors herein disclose new compositions and methods for inhibiting glutaminase activity. The present disclosure relates to new heterocyclic compounds and compositions, and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of GLS 1 activity in a human or animal subject are also provided for the treatment of diseases such as cancer.
Patent AU-2015305610-A1 (AU)
Title: Systems and methods for tissue containment and retrieval
Inventor: DO ALEXANDRA
IPC: A61B17/34
Filed: 2015-08-18
Abstract: Systems and methods for tissue containment and retrieval are disclosed. The containment system includes a primary chamber interconnected with a secondary channel extending from the primary chamber. A tissue specimen is mobilized inside a body cavity and placed into the primary chamber through a first opening. The first opening is pulled through a first incision or orifice and the narrower secondary channel is placed at a second incision or orifice. A second opening at the end of the secondary channel permits observation via a scope inserted through the second opening of the tissue specimen in the primary chamber undergoing morcellation via the first opening. Other systems and methods for deployment, containment, debulking and sealing of the second opening to create a closed system for the safe retrieval of the tissue specimen are provided.
Patent AU-2015316795-A1 (AU)
Title: New polypeptides
Inventor: ABRAHMSEN LARS
IPC: C07K14/735
Filed: 2015-09-17
Abstract: The present disclosure relates to dimers of engineered polypeptides having a binding affinity for the neonatal Fc receptor FcRn, and provides an FcRn binding dimer, comprising a first monomer unit, a second monomer unit and an amino acid linker, wherein said first and second monomer unitseach comprisesan FcRn binding motif. Said FcRn binding dimerbinds FcRn with higher capacity compared to said first monomer unitor second monomer unit alone.The present disclosure also relates to the use of said FcRn binding dimeras an agent for modifying pharmacokinetic and pharmacodynamic properties and as a therapeutic agent.
Patent AU-2015318324-A1 (AU)
Title: Crystalline forms of tyrosine kinase inhibitors and their salts
Inventor: WU JAY JIE-QIANG
IPC: C07D261/20
Filed: 2015-09-02
Abstract: The disclosure relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzoate, including the polymorphic form A, mixtures of the polymorphs, process for the preparation thereof and the use thereof in a pharmaceutical composition containing thereof.
Patent AU-2015326436-A1 (AU)
Title: A method for treating wastewater
Inventor: DE KERCHOVE ALEXIS
IPC: C02F1/52
Filed: 2015-09-28
Abstract: The invention relates to a method for treating wastewater (5). This is achieved by using a coagulant that aggregates a phosphorus- containing substance. The method comprises the step of: executing a reaction phase having a biological treatment phase and a subsequent chemical treatment phase. The chemical treatment phase comprises the first substep of mixing the wastewater (5) while injecting (17) a predetermined dose of the coagulant into the basin (1), the injection (17) taking place at a location (17) in which the speed of the wastewater is equal to or more than 0,5 m/s in order for the coagulant to contact and coagulate the phosphorus-containing substances, wherein the injection (17) of the dose of the binding compound into the basin (1) is performed during a time period equal to or more than a time period required to accomplish two mixing turnovers of the wastewater (5) and equal to or less than a time period required to accomplish seven mixing turnovers of the wastewater (5), and the second substep of mixing the wastewater (5) such that an average speed of the wastewater (5) in the basin (1) is equal to or more than 0,1 m/s and equal to or less than 0,4 m/s, in order to flocculate the coagulated substance.
Patent AU-2015353903-A1 (AU)
Title: Electronic shifting of a transmission
Inventor: NELSON STEPHEN L
IPC: F16H61/02
Filed: 2015-11-18
Abstract: A recreational vehicle (10) is provided including a power source (42), such as an engine or an electric motor, and a transmission (48) having a variable gear ratio. A sub-transmission (56) coupled to an output of the transmission includes a plurality of selectable gear configurations including at least one of a forward gear, a neutral gear, a reverse gear, and a park gear. An electronic controller (36) is operative to electronically control the gear configuration of the sub-transmission.
Patent AU-2015407701-A1 (AU)
Title: Outdoor unit
Inventor: TAKEUCHI Yuto
IPC: F24F1/22
Filed: 2015-08-31
Abstract: This outdoor unit has a first terminal block and a second terminal block which are disposed side by side in the vertical direction, and has a terminal block fixing device provided with a first terminal block fixing plate to which the first terminal block is attached and a second terminal block fixing plate to which the second terminal block is attached. The terminal block fixing device has a first fixing surface of the first terminal block fixing plate and a second fixing surface of the second terminal block fixing plate, the first terminal block being fixed on the first fixing surface, and the second terminal block being fixed on the second fixing surface. The first fixing surface and the second fixing surface are configured at different angles.
Patent AU-2015412144-A1 (AU)
Title: CPU and multi-CPU system management method
Inventor: LIU GANG
IPC: G06F1/32
Filed: 2015-12-29
Abstract: The present invention provides a multi-CPU system, where the multi-CPU system includes: at least two Quick-Path Interconnect QPI domains, a first node controller NC group, and a second node controller NC group; according to a CPU route configuration, there is at least one CPU that 5 can access a CPU in another QPI domain by using the first NC group; and there is at least one CPU that can access a CPU in another QPI domain by using the second NC group. According to this topology, hot swap of an NC can be implemented while the system is relatively slightly affected.
Patent AU-2016200825-A1 (AU)
Title: High dosage mucoadhesive metronidazole aqueous-based gel formulations their use to treat bacterial vaginosis
Inventor: NORDSIEK MICHAEL T
IPC: A01N43/50
Filed: 2016-02-09
Abstract: The present disclosure relates to mucoadhesive aqueous-based homogenous gel formulations of metronidazole (MTZ) for intravaginal application and their uses, for example to treat bacterial vaginosis. Particular compositions comprise high concentration, high dosage, 1% to 2% by weight formulations providing 60mg-Omg MTZ in a single application. These compositions also reduce the incidence of vulvovaginal candidiasis, which is a common occurrence following treatment for bacterial vaginosis. Compositions also comprise mucoadhesive gelling polymers and a solvent system comprising lower aromatic alcohols, lower alkylene diols and polyoxyalkeylenes, wherein the formulation can be free from solubility enhancers such as dextrins, cyclodextrins, niacin, niacinamide and surfactants.
Patent AU-2016200841-A1 (AU)
Title: Method for acquiring geophysical data by dynamically manipulating survey spread
Inventor: MALLING MICHAEL
IPC: G01V1/38
Filed: 2016-02-10
Abstract: Embodiments relate generally to marine geophysical surveying and, more particularly, embodiments relate to methods for acquiring geophysical data by dynamically manipulating survey spread in response a change in location of a target. A method may comprise actuating an energy source in a body of water, wherein a target for a marine geophysical survey system is located beneath a bottom of the body of water. The method may further comprise detecting energy generated by the energy source. The method may further comprise manipulating a position of a survey spread in response to a change in distribution of the target beneath the bottom of the body of water. 1 05,- -11510 7/K~-- 40--10 * -- 14 5/ 140140
Patent AU-2016201722-A1 (AU)
Title: Cancer immunotherapy and method of treatment
Inventor: BOT ADRIAN ION
IPC: A61K39/00
Filed: 2016-03-17
Abstract: H:\seh\Introvn\NRPortbl\DCC\SEH\983418 II.docx-17/03/2016 Abstract The instant disclosure relates to method for treating a cancer patient with an active immunotherapeutic, wherein the method include assessing a patient's pre-existing immunoreactivity to at least one target antigen, choosing an immunotherapeutic regimen based on the level of pre-existing immunoreactivity, and administering an active immunotherapeutic according to the regimen.
Patent AU-2016210755-A1 (AU)
Title: SIRP-alpha variant constructs and uses thereof
Inventor: DEMING LAURA
IPC: A61K38/17
Filed: 2016-08-05
Abstract: SIRP-ALPHA VARIANT CONSTRUCTS AND USES THEREOF The invention relates to compositions and methods of SIRP-a variant constructs including SIRP-a variants. The SIRP-a variant constructs may be engineered in a variety of ways to respond to environmental factors, such as pH, hypoxia, and/or the presence of tumor-associated enzymes or tumor associated antigens. The SIRP-a variant constructs of the invention may be used to treat various diseases, such as cancer, preferably solid tumor or hematological cancer. (4 (D4 U
Patent AU-2016214178-A1 (AU)
Title: Instrument for performing a diagnostic test on a fluidic cartridge
Inventor: ARLETT BEN
IPC: B01L7/00
Filed: 2016-02-02
Abstract: Instrument for performing a diagnostic test on a fluidic cartridge A cartridge reader is for carrying out a diagnostic test on a sample contained in a fluidic cartridge inserted into the reader. The fluidic cartridge comprises a fluidic layer comprising at least one sample processing region, at least one collapsible blister containing a liquid reagent, a pneumatic interface, an electrical interface and at least one mechanical valve. The reader comprises a housing; an upper clamp occupying a fixed position relative to the reader, anda lower clamp, movable relative to the first clamp, wherein the upper clamp and the lower clamp define a cartridge receiving region therebetween. The reader comprises a thermal module comprised in the lower clamp, wherein the thermal module comprises at least one thermal stack for heating the at least one sample processing region of the cartridge inserted into the reader. The reader comprises at least one mechanical actuator for actuating the mechanical valve comprised in the cartridge inserted into the reader.
Patent AU-2016215158-A1 (AU)
Title: Reliable control of high rotor pole switched reluctance machine
Inventor: KRISHNAMURTHY MAHESH
IPC: H02P6/185
Filed: 2016-02-04
Abstract: A system and method for reliable control of a high rotor pole switched reluctance machine (HRSRM) utilizing a sensorless reliable control system. The method comprising: energizing at least one of the plurality of stator phases; measuring a first current value and time taken by the first current value to reach a first peak value or preset threshold value of current; determining a self-inductance value; storing the self-inductance value and the first current value for each of the stator phases; measuring a second current value and time taken by an adjacent un-energized stator phase to reach a second peak value of current; determining a mutual inductance value; storing the mutual inductance value and the second current value for each of the stator phases; estimating a rotor position utilizing the self- inductance and mutual inductance values; and controlling the HRSRM based on the estimated rotor position.
Patent AU-2016231600-A1 (AU)
Title: Talent Share
Inventor: BOOTHROYD ANDREW
IPC: G06Q30/02
Filed: 2016-09-22
Abstract: TALENT SHARE TalentShare will be the first platform (website & app) for the entertainment industry, giving live music, drama, dance, poets, fire artists and many more the opportunity to share their skills to everyone. Their profile on the platform is free for them to advertise & promote themselves. Anybody then hosting a party, venues, corporate functions, pubs, clubs will be able to view all performers in one place & book them if their available using the platform.
Patent AU-2016245324-A1 (AU)
Title: Conveyor pulley monitoring apparatus
Inventor: LUTZU ANTONIO
IPC: B65G39/02
Filed: 2016-04-08
Abstract: A monitoring apparatus for a conveyor pulley, wherein the conveyor pulley is fastened to a pulley shaft using a locking device. The monitoring apparatus comprises sensing means capable of detecting and measuring one or more physical phenomena, activities or conditions associated with the conveyor pulley. The sensing means are integrated into a protective cover of the locking device.
Patent AU-2016246120-A1 (AU)
Title: Safety capsule for a container
Inventor: PAGANUZZI VALERIO
IPC: B65D50/04
Filed: 2016-03-30
Abstract: A safety capsule for a container, comprising: a cap (2) for closing the container, said cap comprising a thread (20) for connection to the container; a cover (3) for said cap (2), said cover (3) comprising a base (30) and a lateral wall (31 ) that extends from said base (30); said base (30) and said lateral wall (31 ) overlying said cap (2), said base (30) being at the opposite end with respect to a zone (4) of the capsule that comprises an intactness band (8) designed to be connected with the container; a press-fit engagement means (5) that sets said cap (2) and said cover (3) into operative communication, enabling transmission of motion from the cover (3) to the cap (2) for the purpose of making it possible to unscrew said cap (2); means (6) for preventing extraction of the cover (3) from the cap (2), comprising a first connecting means (61 ) for connecting the cover (3) to the cap (2) and that extends along a first imaginary annular line; the engagement means (5) and said first connecting means (61 ) being at least partly incorporated in said cap (2) and cover (3); means (27) for re-closing the cap (2) on the container after it has been opened, and comprising first and second flexible tabs (23, 32) incorporated on the cap (2) and on the cover (3), respectively.
Patent AU-2016268388-A1 (AU)
Title: Dispersions of holey graphene materials and applications thereof
Inventor: DUAN XIANGFENG
IPC: C01B32/192
Filed: 2016-05-26
Abstract: A method of forming a graphene-based material includes: (1) treating a mixture including an etchant and graphene oxide sheets to yield formation of holey graphene oxide sheets; (2) dispersing the holey graphene oxide sheets in a re-dispersal solvent to yield a holey graphene oxide dispersion including the holey graphene oxide sheets; and (3) treating the holey graphene oxide dispersion under reducing conditions to yield self-assembly of the holey graphene oxide sheets into a graphene-based material.
Patent AU-2016269641-A1 (AU)
Title: Systems and methods for conducting secure VOIP multi-party calls
Inventor: FER FRANCOIS
IPC: H04L29/06
Filed: 2016-05-27
Abstract: System and method for establishing secure conference calls. In one example system, a central conference call server establishes point-to-point connections with accessory devices comprising a secure element and connected to corresponding participant devices. The conference call server includes an interface to a plurality of secure elements configured to perform scrambling and unscrambling of media signals communicated to and from the accessory devices. In another example, one of the participant devices operates as the central conference call server. In other examples, participant devices communicate on a conference call via point-to-point connections between all accessory devices connected to the participant devices. The accessory devices include secure elements for decryption and encryption of media signals communicated between the accessory devices.
Patent AU-2016287728-A1 (AU)
Title: Confidential authentication and provisioning
Inventor: LE SAINT ERIC
IPC: H04L9/32
Filed: 2016-06-30
Abstract: Some embodiments provide systems and methods for confidentially and securely provisioning data to an authenticated user device. A user device may register an authentication public key with an authentication server. The authentication public key may be signed by an attestation private key maintained by the user device. Once the user device is registered, a provisioning server may send an authentication request message including a challenge to the user device. The user device may sign the challenge using an authentication private key corresponding to the registered authentication public key, and may return the signed challenge to the provisioning server. In response, the provisioning server may provide provisioning data to the user device. The registration, authentication, and provisioning process may use public key cryptography while maintaining confidentiality of the user device, the provisioning server, and then authentication server.
Patent AU-2016318210-A1 (AU)
Title: Modulable sports wheelchair
Inventor: FONTANESI SIMONE
IPC: A61G5/02
Filed: 2016-09-01
Abstract: The invention relates to a modulable sports wheelchair comprising a supporting frame, a front wheel, a pair of rear wheels and a sitting cage. The supporting frame is divided into a front half-frame connecting a support for the front wheel with a frame structure carrying the rear wheels. The frame structure has at least two longitudinal sides oriented in the movement direction of the wheelchair and two transverse sides spaced and oriented in the other direction such to form the cage, that therefore takes the shape of a compartment free from internal structural elements intended to receive an athlete with an optimal position for propelling the wheelchair depending on the level and type of disability of the athlete.
Patent AU-2016338775-A1 (AU)
Title: Pumps
Inventor: BORG DUSTIN
IPC: F04D29/32
Filed: 2016-10-11
Abstract: Pump designs are detailed. A pump may include a fan having one or more pass-through holes allowing ambient air to be drawn through a fan near a motor shaft bearing for cooling purposes. Alternatively or additionally, a pump may include modular stages to facilitate servicing and repair.
Patent AU-2016339949-A1 (AU)
Title: Single cell microfluidic device
Inventor: LEE ABRAHAM P
IPC: B01L3/00
Filed: 2016-10-12
Abstract: Methods of non-destructively obtaining the genotype of a plant cell from a plant sample are disclosed. The plant cell is isolated from a plant cell sample using an integrated microfluidic device. The integrated microfluidic device includes an individual cell trap located downstream from a microfluidic channel and, the microfluidic device is configured to trap the plant cell in the individual cell trap. mRNA is extracted from the plant cell by contacting the plant cell with an atomic force microscope (AFM) probe and by attracting mRNA from loci of interest to the probe end using a dielectrophoresis DEP force under the alternating current (AC) field applied to the probe. The genotype of the plant cell is determined from cDNA obtained from the extracted mRNA. Alternatively, the mRNA is analyzed to determine gene expression patterns of the plant cell.
Patent AU-2016340992-A1 (AU)
Title: Improved synthesis of honokiol
Inventor: JARACZ STANISLAV
IPC: A61K31/05
Filed: 2016-10-21
Abstract: Disclosed herein are improved methods for the synthesis of honokiol, as well as methods for the synthesis of 3,3'-di-tert-butyl-5,5'-dimethyl-[1,1'-biphenyl]-2,4'-diol, 3',5-dimethyl-[1,1'-biphenyl]-2,4'-diol, and 2,4'-dimethoxy-3',5-dimethyl-1,1'-biphenyl, 3,3',5,5'-tetra-tert-butyl-[1,1'-biphenyl]-2,4'-diol, and certain tetrasubstituted bisphenols, and uses therefor.
Patent AU-2016345552-A1 (AU)
Title: Sustained-release non-steroidal anti-inflammatory drug delivery
Inventor: NISKANEN ELINA
IPC: A61K47/02
Filed: 2016-10-31
Abstract: According to an example aspect of the present invention, there is provided a depot suitable for sustained-release drug delivery, said depot comprising a composite body comprising particles having at least one encapsulated active pharmaceutical ingredient The depot comprises 50 to 95 wt% of the composite body particles, said composite body particles comprising 0.1 to 80 wt% of active pharmaceutical ingredient, and the active pharmaceutical ingredient is a non-steroidal anti-inflammatory drug.
Patent AU-2016379332-A1 (AU)
Title: Trim dewaxing of distillate fuel
Inventor: PODSIADLO PAUL
IPC: C10G45/08
Filed: 2016-12-20
Abstract: Methods and catalysts are provided for performing dewaxing of diesel boiling range fractions, such as trim dewaxing, that allow for production of diesel boiling range fuels with improved cold flow properties at desirable yields. In some aspects, the methods can include use of dewaxing catalysts based on an MEL framework structure (ZSM-11) to provide improved dewaxing activity. In some aspects improved dewaxing is achieved operating at lower pressures and with higher amounts of organic nitrogen slip from hydrotreatment.
Patent AU-2016407730-A1 (AU)
Title: A new anti-foaming composition
Inventor: MAEKER DIANA
IPC: C09K8/60
Filed: 2016-05-25
Abstract: The present invention relates to an anti-foaming composition comprising an alkoxylated stand oil and/or an alkoxylated blown native oil and use thereof as an anti-foaming agent.
Patent WO-2017214676-A1 (WO)
Title: Unité de commande d'optimisation de module unique apte à faire fonctionner l'un parmi une pluralité de types différents de systèmes hvacr
Inventor: ROGERSON CHRISTOPHER JAMES
IPC: G05B15/02
Filed: 2017-06-15
Abstract: La présente invention concerne une unité de commande d'optimisation d'unité unique (100) apte à faire fonctionner un type connu quelconque de système de chauffage, de ventilation, de climatisation et de réfrigération HVACR (un système HVACR est représenté par le numéro de référence (101)), qui comprend tous les systèmes ACR. Le système HVACR (101) est sous la forme d'une unité de climatisation. L'unité de commande comprend une section de communication (102) pour communiquer avec un ou plusieurs terminaux d'unité de commande à distance sous la forme d'une application Web (103), et une section de commande (104). L'unité de climatisation du système HVACR (101) comprend au moins une unité de refroidissement comportant un compresseur, la section de commande étant associée de manière fonctionnelle au système HVACR (101) pour sélectivement activer ou désactiver ladite unité de refroidissement sur la base d'un ou plusieurs réglages reçus en provenance de l'application Web (103) par l'intermédiaire de la section de communication (102).
Patent WO-2018000031-A1 (WO)
Inventor: GOH SU KAH
IPC: C12Q1/68
Filed: 2017-06-27
Abstract: The present disclosure relates to the use of donor-specific cell-free DNAfor detecting organ transplant rejection, organ dysfunction or organ failure as well as organ transplant health. Donor-specific cell-free DNA is quantified using a probe-free quantitative PCR comprising the use of allele specific forward or reverse primers which fully hybridise to at least one donor specific deletion/insertion (DIP) allelic sequence.