baber/WOPTO huggingface dataset:
Patent SK-285135-B6 (SK)
Title: 1,3-Propane diol derivative and its use
Inventor: HORROBIN DAVID FREDERIK
IPC: A61K31/00
Filed: 1996-05-01
Abstract: Described is 1,3-propane diol derivative of structure (I), where R1 comprises an acyl group or aliphatic alcohol group derived from C12-30 preferably C16-30 fatty acid with two or more cis or trans double bonds and R2 is hydrogen or comprises an acyl group or aliphatic alcohol group as R1 the same or different, any other nutrient, drug or other bioactive residue for the manufacture of a medicament. There is also described the use of the 1,3-propane diol derivative for the manufacture of a medicament for therapy involving transport of a drug across lipid membranes.
Patent SK-277965-B6 (SK)
Title: METHOD OF PREPARATION OF CLONING SYSTEM cDNA FOR TRANSFORMATION AND EXPRESSION cDNA OF OVALBULINE OF COTURNIX JAPONICA IN PLANTS
Inventor: SIMUTH JOZEF
IPC: C12N15/82
Filed: 1992-12-30
Abstract: From vector pT4, containing cDNA is gained the fragment of of cDNA with partially splitting fragment cDNA, the gained fragment is after isolation cloned in to cloning place of plasmide PA 35, containing the promoter of mosaic virus of cauliflower CaMV35 S with dimension 560 bp and noncoding area of nopaline gene NOP, by origin of vector pPA 35 characterized by splitting with specific restrictive endonucleases, from vector pPA35 is by splitting with Eco RI and Hind III the express cassette CaMV 35 S-cDNA -NOP is splitedit is cloned in to Eco RI and Hind III of cloning place of plasmide pDE 1001, containing the gene for resistance to kanamicine and the cells of E. coli are transformed with gained vector from this cells vector pPDE 1001, containing express cassette cDNA and is isolated and integrated with pertaining carrier.
Patent SK-287607-B6 (SK)
Title: Method for locating compounds which are suitable for the treatment and/or prophylaxis of obesity
Inventor: HEBEBRAND JOHANNES
IPC: A61P1/00
Filed: 2001-07-12
Abstract: The method for locating compounds which are suitable for the treatment and/or prophylaxis of obesity, whereby the ability of the examined compounds to inhibit de novo lipogenase in mammals and/or humans is determined. Also disclosed is the use of compounds which are capable of inhibiting de novo lipogenase in mammals in the production of medicaments for the treatment and/or prophylaxis of obesity.
Patent CZ-306876-B6 (CZ)
Title: A non-dairy sunflower drink and the method of its production
Inventor: OUHRABKOVÁ JARMILA
IPC: A23C11/02
Filed: 2010-04-12
Abstract: The non-dairy sunflower drink is characterized by the fact that its base comprises 10.1 to 20 wt% of husked sunflower seeds in water, into which, after homogenization, up to 15 wt% of sugar and 0.03 to 0.05 wt% of common salt, optionally various flavourings and fortifying agents, are added.
Patent CZ-306525-B6 (CZ)
Title: A differential front planet gearbox with power split into two branches for driving the movement of the face worm of a coal cutter, especially in low seams
Inventor: ČERNÝ IVO
IPC: F16H37/08
Filed: 2016-09-15
Abstract: The differential front planet gearbox with power split into two branches for driving the movement of the face worm wheel of a coal cutter, especially in low seams contains the gearbox (7) which is fitted, on the input side (71), with the input pinion (101), and, on the output side, (72) with the first and second face worm pinions (3) and (4), which are at the same time directly meshed with the face worm wheel (2). The input pinion (101) is fitted with the primary front transmission (10) whose output wheel (103) is placed in the first axis of rotation (11). In the first axis of rotation (11), there are, in the in the subsequent order, further located also the differential planet transmission (20), the first planet transmission (30) and the first face worm pinion (3). The gearbox (7) also contains the secondary front transmission (50) with the input consisting of the pinion (207) of the differential planet transmission (20), which meshes with at least the output wheel (503) of the secondary front transmission (50). The output wheel (503) of the secondary front transmission (50) is placed in the second axis of rotation (12). In the second axis of rotation (12), there are, in the subsequent order, located also the secondary planet transmission (40) and the second face worm pinion (4).
Patent SK-285652-B6 (SK)
Title: Ultraphobic surface
Inventor: REIHS KARSTEN
IPC: C09K3/18
Filed: 1999-12-22
Abstract: A structured surface with ultraphobic properties has a surface topography in which the value of the integral of a function S(log f) = a(f).f, which gives a relationship between the spatial frequencies f of the individual Fourier components and their amplitudes a(f) is at least 0.5 between the integration limits log (f1/mu m-1) = -3 and log(f2/mu m-1) = 3. The surface consists of a hydrophobic or oleophobic material or is coated with a hydrophobic or oleophobic material.
Patent CZ-295470-B6 (CZ)
Title: Process for producing mica-containing insulating tapes, and the use of such tapes
Inventor: GSELLMANN HELMUT
IPC: H01B17/60
Filed: 1999-10-13
Abstract: 136:$Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided, as are methods for their preparation and for inhibiting the first-pass effect.
Patent CZ-289546-B6 (CZ)
Title: Lifting device
Inventor: ALTEN FERDINAND
IPC: B62D43/06
Filed: 2000-09-22
Abstract: In the present invention there is disclosed a lifting device for placing a spare wheel beneath a floor (1) of a vehicle. The device has a mounting plate (3) or frame for a spare wheel, whereby the mounting plate (3) or the frame is raised and lowered through the mediation of a cable (6) moved by a winch (8) and a locking bar that secures the lifting device from falling out when in the raised stowed position, whereby the locking bar is moved with the cable winch (8) by a drive element connected to the winch (8) by friction.
Patent CZ-298805-B6 (CZ)
Title: Arylalkanoyl pyridazine derivative, process of its preparation and pharmaceutical preparation in which it is comprised
Inventor: JONAS ROCHUS
IPC: A61P37/06
Filed: 1999-05-07
Abstract: In the present invention, there is disclosed an arylalkanoyl pyridazine derivative of the general formula I, in which B represents phenyl being unsubstituted or substituted with one or several Re3 groups, Q is missing or represents alkylene containing 1 to 4 carbon atoms, Re1 and Re2 represent independently on each other the group ORe4, -S-Re4, -SO-Re4, -SOi2-Re4 or Hal, Re1 and Re2 together can also represent -O-CHi2-O-,Re3 denotes the group Re4, Hal, OH, ORe4, OPh, NOi2, NHRe4, N(Re4)i2, NHCORe4, NHSOi2Re4 or NHCOORe4, Re4 represents the group A, cycloalkyl having 3 to 7 carbon atoms, alkylenecycloalkyl containing 5 to 10 carbon atoms in the alkylene moiety or alkenyl containing 2 to 8 carbon atoms, A denotes alkyl having 1 to 10 carbon atoms being optionally substituted with one to five fluorine and/or chlorine atoms, Hal is a fluorine, chlorine, bromine or iodine atom, and physiologically acceptable salts and solvates thereof are suitable, as phosphodiesterase IV inhibitors, for the preparation of pharmaceutical compositions intended for treating various diseases, such as allergies, asthma, chronic bronchitis, atopic dermatitis, psoriasis and other skin diseases, further inflammatory diseases, autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, Crohn's disease, diabetes mellitus or ulcerative colitis, osteoporosis, transplant rejection reactions, cachexia, tumor growth and metastases, sepsis, dysmnesia, atherosclerosis and AIDS.
Patent CZ-302012-B6 (CZ)
Title: Piperidine derivative and its use, process and intermediate for its preparation and pharmaceutical composition in which the derivative is comprised
Inventor: BREU VOLKER
IPC: A61P27/06
Filed: 2000-04-19
Abstract: In the present invention, there is disclosed piperidine derivative of the general formula I, wherein Re1 denotes naphthyl being optionally substituted with one to three alkoxy group containing 1 to 5 carbon atoms; Re2 represents phenyl or benzyl, optionally substituted by substituents independently selected from one to three halogen, cyano, Cl-C3-alkoxy and nitro groups; Re3 denotes H-[CH(ORe4)]i2, -CHi2 -O-CHi2- or Re3a-(CHi2)ik-[CH(ORe4)]i1-CHi2-O-; Re3a represents OH an alkoxy group having 1 to 3 carbon atoms; Re4 denotes hydrogen or alkyl containing 1 to 3 carbon atoms; k is 1 or 2, when R3a is hydrogen, k is 0; 1 is 1 or 2; and pharmaceutically acceptable salts thereof. There is also disclosed a process for preparing the above-described derivative by deprotecting the compound of the general formula II, intermediate of the general formula II as well as a pharmaceutical composition in which the derivative of the general formula I is comprised.
Patent CZ-297472-B6 (CZ)
Title: Process for preparing crystalline form I of clopidogrel hydrogen sulfate
Inventor: VEVERKA MIROSLAV
IPC: C07D495/04
Filed: 2002-08-27
Abstract: In the present invention, there is disclosed a process for preparing hydrogen sulfate (alpha S) of the alpha-(2-chlorophenyl)-6,7dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid methyl ester (clopidogrel hydrogen sulfate) of the general formula I, in crystalline form I, wherein the compound of the general formula I is separated out of a solution of clopidogrel in the form of a free base or a salt in a solvent selected from the series of primary, secondary or tertiary alcohols containing 1 to 5 carbon atoms, their esters with carboxylic acids having 1 to 4 carbon atoms or optionally from mixtures thereof.
Patent CZ-299154-B6 (CZ)
Title: Method for operating a windmill generating station system and windmill generating station system per se
Inventor: WOBBEN ALOYS
IPC: F03D9/25
Filed: 2002-04-12
Abstract: The invented method for operating a windmill generating station system with an electric generator driven by a rotor for the production of electrical power for an electrical user, in particular an electrical network is characterized in that in case of a short circuit within the electrical network or a similar operating failure during which voltage deviates by more than 20 percent from a reference value, an actuating and regulating device (10) switches on (10). The aim of this device is to regulate electric power supply to the network (6) without exceeding predetermined threshold values of current supplied to the network by the electric generator (12). The invention also relates to such windmill generating station system provided with an electric generator that is permanently connected to an electrical network (6) even when a short circuit or the like operating failure occurs and voltage deviates by more than 20 percent from a reference value. Such system comprises an actuating and regulating device (10) situated if front of external input (22) in the network (6) and intended for regulating delivery of electric power to the network (6) and to supplementing the network (6). Current supplied by the electric generator (12) achieves in case of a short circuit or another operation failure a predetermined threshold value.
Patent CZ-303422-B6 (CZ)
Title: Epothilone C, process for its preparation and its use as cytostatic and plant protection composition
Inventor: REICHENBACH HANS
IPC: C12P17/16
Filed: 1997-11-18
Abstract: The present invention relates to epothilone C of the indicated formula, process for its preparation, plant protection composition and a therapeutic agent intended for use as cytostatic containing the epothilone C.
Patent JP-6749741-B6 (JP)
Title: 気体噴出装置
IPC: B05B3/06
Filed: 2019-10-01
Granted: 2021-06-23
Abstract: 【課題】  気体を物体して噴射するためのノズルおよび気体噴出装置を提供すること。 
【解決手段】本発明のノズル１２０は、回転しながら空気流を噴射し、気体を受け入れる流体流路を備え、回転可能に保持された回転体１２６と、回転体１２６から内部が遮られずに延び、気体をオリフィス１２１ａ，１２ａｂから噴射させるノズル部材１２７と、回転体１２６およびノズル部材１２７を収容する保護カバー１３０と保護カバー内部で、オリフィス１２１ａ，１２１ｂを収容する空間を画定する底板１３１と、を備え、ノズル部材１２７は、回転体１２６に接合され、回転体１２６との接合部からノズル部材１２７の内径を保持してオリフィス１２１ａ，１２１ｂまで屈曲して延びている。 
【選択図】図４
Patent BR-PI0110506-B8 (BR)
Title: uso de inibidores de il-18 para o tratamento e/ou prevenção da aterosclerose
Inventor: ALAIN TEDGUI
IPC: A61K31/616
Filed: 2001-04-30
Abstract: "uso de inibidores de il-18 para o tratamento e/ou prevenção da aterosclerose". a invenção refere-se ao uso de um inibidor de il-18 para produção de um medicamento no tratamento e/ou prevenção da aterosclerose.
Patent BR-PI0313763-B8 (BR)
Title: imidazóis 2,4,5-trissubstituídos, seus usos, e composições farmacêutica e anti-microbiana
Inventor: AIPING H YOUNG
IPC: A23L3/3544
Filed: 2003-08-19
Abstract: imidazóis 2,4,5-trissubstituídos e seu uso como agentes antimicrobianos. a presente invenção refere-se a compostos de imidazol 2,4,5-trissubstituídos terapeuticamente eficazes, métodos de preparação do mesmo, e composições compreendendo os compostos sozinhos ou em combinação com outros agentes. a presente invenção provê ainda o uso dos compostos como agentes antimicrobianos. as propriedades antimicrobianas dos compostos incluem atividades antibacterianas e/ou antifúngicas.
Patent BR-PI9912177-B8 (BR)
Inventor: CHANG YI WANG
IPC: C07K14/47
Filed: 1999-06-21
Abstract: The present invention is directed to novel artificial T helper cell epitopes (Th epitopes) designed to provide optimum immunogenicity when used in peptide immunogens comprising B cell epitopes or peptide haptens, a target antigenic site of a target antigen for eliciting antibodies thereto. The artificial Th epitopes are covalently linked to the target antigenic site and optionally an immunostimulatory sequence to provide effective and safe peptide immunogens.
Patent DE-19616528-B8 (DE)
Inventor: BELLINGROEHR NORBERT
IPC: B21D51/46
Filed: 1996-04-25
Granted: 2012-01-05
Abstract: The invention relates to press-in lids for forming a snug sealing fit therebetween, the internal wall (20b) and a cover ring (30, 30a, 30b) which has two vertical wall sections pointing upwards. The object of the invention is to act against quick-leak filling fluids, paints or glazes by sealing means but that it should be possible to re-close the press-in lid so that the seal provided is just as efficient. It should also be possible to print on or coat the cover surface (20a) of the press-in lid (20, 20a, 20b), it being possible to dry or bake said print or coating at a high temperature to provide externally information identifying the container contents sealed by the lid. It is also proposed to provide a press-in lid which does not have a coating in the edge region thereof or only has a internal lacquer coating (22b, 22). A thin layer (32, 32a) protecting against leakage is only applied to sides of the cover ring on its vertical inner wall (30b). Said layer protecting against leakage consists, in particular, of polypropylene. The snug sealing fit is achieved between the vertical wall (20b) of the press-in lid and the thin layer protecting against leakage on the cover ring.
Patent EP-1319719-B8 (EP)
Inventor: SOBEK HARALD DR
IPC: C12N9/99
Filed: 2002-11-30
Granted: 2008-08-27
Abstract: The invention relates to a composition comprising a first modified thermostable enzyme exhibiting 3'exonuclease activity but essentially no DNA polymerase activity and a second modified thermostable enzyme exhibiting DNA polymerase activity, whereas the fidelity of an amplification process is enhanced by the use of the composition in an amplification process in comparison to the use of the single second enzyme in an amplification process and, whereas said first and said second modified thermostable enzyme is reversibly modified by an inhibiting agent which results in essentially complete inactivation of enzyme activity, wherein incubation of said first and said second modified thermostable enzyme in an aqueous buffer at alkaline pH at a temperature less than 25  DEG C for 20 minutes results in no significant increase in the activity of said first and said second modified thermostable enzyme, wherein incubation at a temperature greater than 50  DEG C in an aqueous buffer at alkaline pH results in at least tow-fold increase in enzyme activity in less than 20 minutes which allow formation of primer extension products.
Patent EP-1410721-B8 (EP)
Inventor: KOWALCZYK JOERG DR
IPC: A23L33/00
Filed: 2003-09-04
Granted: 2006-10-25
Abstract: Production of an enteral nutrition product from a mixture of water, fat, nitrogenous material and carbohydrates (including isomaltulose) comprises pasteurizing the mixture at at least 135degreesC for 10-30 seconds or autoclaving the mixture at at least 120degreesC for 5-15 minutes. The mixture is homogenized before or after pasteurization or autoclaving.
Patent EP-1911348-B8 (EP)
Inventor: NING TAO
IPC: A01K89/01
Filed: 2006-03-06
Granted: 2012-03-07
Abstract: A modularized fishing reel spool comprises a drag adjust knob, a brake device having two springs and washer stacks, a front lid, a core and a skirt. A turning support system of the spool comprises a two bearing system, a main shaft and a core shaft. Compared to conventional fishing reel spools, this invention provides a spool having advantages such as better structural design, wider adjustable brake range, superior line-loading force application, well-functioned water drainer system, low manufacturing cost and lower material usage.
Patent BR-PI0717208-B8 (BR)
Title: mistura fungicida, composição fungicida e método para o controle de doenças vegetais
Inventor: WONPYO HONG
IPC: A01N35/04
Filed: 2007-11-15
Abstract: MISTURA FUNGICIDA, COMPOSIÇÃO FUNGICIDA E MÉTODO PARA O CONTROLE DE DOENÇAS VEGETAIS. A presente invenção se refere a uma mistura fungicida que compreende (a) pelo menos um composto selecionado a partir dos compostos de Fórmula (1) N-óxidos, e seus sais, (1) em que G, D, R1 e R5 são definidos neste relatório descritivo, e (b) o composto de Fórmula (2), (2) e opcionalmente (c) um ou mais compostos descritos na descrição. Também está descrita uma composição fungicida que compreende uma quantidade eficaz como fungicida da mistura mencionada acima e pelo menos um componente adicional selecionado a partir do grupo que consiste em tensoativos, diluentes sólidos ou diluentes líquidos. Também está descrito um método para o controle das doenças vegetais causadas pelos patógenos fúngicos de vegetais que compreende a aplicação no vegetal ou em sua porção, ou na semente vegetal, de uma quantidade eficaz como fungicida da mistura mencionada acima (por exemplo, como uma composição descrita no presente).
Patent AU-2017348322-B8 (AU)
Title: Compositions and methods for treating EZH2-mediated cancer
Inventor: JIN JIAN
IPC: C07D401/12
Filed: 2017-10-27
Granted: 2021-12-23
Abstract: Methods for designing bivalent compounds which selectively degrade/disrupt EZH2 and compositions and methods of using such degraders/disruptors to treat EZH2-mediated cancer are provided.
Patent EP-1329458-B9 (EP)
Inventor: LARSEN BJARNE DUE
IPC: A61K38/22
Filed: 2000-07-12
Granted: 2012-09-12
Abstract: The present invention relates to novel peptide conjugates which have increased stability and are useful in the treatment of excess levels of blood glucose.
Patent EA-032501-B9 (EA)
Title: Methods and compositions for promoting acute wound and chronic wound healing
Inventor: REDDELL PAUL WARREN
IPC: C07D493/14
Filed: 2014-04-17
Abstract: The present invention relates to epoxy-tigliane compounds and their use in promoting acute wound and chronic wound healing. In particular embodiments, the epoxy-tigliane compounds are epoxy-tigliaen-3-one compounds. Methods of inducing or promoting acute wound and chronic wound healing as well as methods of reducing scarring and improving cosmetic outcomes upon healing of an acute wound and chronic wound are described. Compounds and compositions for use in acute wound and chronic wound healing are also described.
Patent DE-102007020207-B9 (DE)
Title: Werkzeug zur Beseitigung von Grat an den Stoßkanten von schräg verlaufenden Querbohrungen
Inventor: BEIER HANS-MICHAEL
IPC: B23B51/10
Filed: 2007-04-28
Granted: 2012-10-25
Abstract: Werkzeug zur Beseitigung von Grat an den Stoßkanten von schräg verlaufenden Querbohrungen mit einem Durchmesser von kleiner 10 mm in einem Bauteil, wie einem Motorblock, einem Einspritzsystem, einem Ventilblock, einer Kurbel- oder Getriebewelle, welches beim Einsatz rotatorisch und/oder translatorisch bewegt wird, aus einem Werkzeugschaft (1) mit Einspannende (2) und einem am werkzeugseitigen Schaftende als festes Lager angeordneten Stützkörper (6) besteht und mit einem rohrförmigen Schaftstück (11) verbunden ist oder das werkzeugseitige Schaftende als rohrförmiges Schaftstück (11) weitergefüh (6) mit einem Stift (7) verschlossen ist oder das Einspannende ein rohrförmiger, druckaufnehmender Schaft ist, der durch ein oder mehrere druckabbauende Spiralspannstifte mit einem werkzeugseitigen Schaftende, das einen einschiebbaren elastischen Stützkörper lose aufnimmt, verbunden ist, wobei das Schaftstück/Schaftende (11) mindestens einen in einem Durchbruch (9) beweglich gelagerten Schneidenkörper (8) mit einer Schneide (3), der eine Schulter aufweist, hält und ein unter Druck in die Durchgangsbohrung (5) des...
Patent DE-102014101539-B9 (DE)
Title: Warmformlinie und Verfahren zur Herstellung von warmumgeformten Blechprodukten
Inventor: NIESSE MAX
IPC: C21D8/02
Filed: 2014-02-07
Granted: 2016-08-11
Abstract: Warmformlinie mit einer Heizstation (1) und einer Umformstation (2) zur Herstellung von warmumgeformten und pressgehärteten Blechprodukten (31) aus Metallplatinen (6), wobei die Heizstation (1) ein Unterwerkzeug (3) und ein Oberwerkzeug (4) aufweist zwischen denen eine Metallplatine (6) zum Erwärmen aufnehmbar ist und das Unterwerkzeug (3) und/oder das Oberwerkzeug (4) eine elektrische Widerstandsheizung (7) mit zumindest einem Flächenheizelement aufweist und das Flächenheizelement eine Heizplatte (8, 8', 35, 40) ist, dadurch gekennzeichnet, dass die Heizplatte (8, 8', 35, 40) als Plattenkörper (9, 36, 41) aus einem elektrisch leitfähigen Material und der Plattenkörper (9, 36, 41) als Heizleiter (11, 38, 47) ausgebildet ist, wobei der Heizleiter (11) eine Länge besitzt, die länger ist als der kürzeste Abstand (k1, k2, k3, k4) zwischen den elektrischen Kontakten (12, 13) des Heizleiters (11).
Patent DE-112012001920-B9 (DE)
Title: Strahlung emittierender Halbleiterchip mit integriertem ESD-Schutz
Inventor: LÖFFLER ANDREAS
IPC: H01L33/14
Filed: 2012-04-26
Granted: 2021-07-22
Abstract: Strahlung emittierender Halbleiterchip (1) mit einer auf einem Nitrid-Verbindungshalbleitermaterial basierenden Halbleiterschichtenfolge (2) mit einem pn-Übergang umfassend- eine erste Schutzschicht (3), die gezielt eingebrachte Kristalldefekte (4) aufweist,- eine zweite Schutzschicht (5), die eine höhere Dotierung (n2) aufweist als die erste Schutzschicht (3), wobei die erste Schutzschicht (3) zum Schutz des Halbleiterchips (1) vor elektrostatischen Entladungspulsen vorgesehen ist,- eine aktive Zone (7) zur Strahlungserzeugung, die der ersten Schutzschicht (3) in Wachstumsrichtung (W) nachgeordnet ist, wobei- die Halbleiterschichtenfolge (2) eine weitere Schutzschicht (12) aufweist, wobei die weitere Schutzschicht (12) eine niedrigere Dotierung aufweist als die erste Schutzschicht (3),- die zweite Schutzschicht (5) zwischen der ersten Schutzschicht (3) und der aktiven Zone (7) angeordnet ist,- eine Injektionsschicht (6) zwischen der zweiten Schutzschicht (5) und der aktiven Zone (7) angeordnet ist,- die weitere Schutzschicht (12) zwischen der Injektionsschicht (6) und der aktiven Zone (7) angeordnet ist, und- im Betrieb des Halbleiterchips (1) ein elektrischer Widerstand der Halbleiterschichtenfolge (2) in Sperrrichtung in Bereichen mit Kristalldefekten (4) gegenüber Bereichen ohne Kristalldefekte (4) verringert ist, und die zweite Schutzschicht (5) aufgrund der höheren Dotierung den Stromfluss homogenisiert, so dass bei elektrostatischen Entladungspulsen elektrische Ladung homogen verteilt über die Bereiche mit Kristalldefekten (4) abgeleitet wird.