baber/WOPTO huggingface dataset:
Patent EP-0333282-B1 (EP)
IPC: A01N37/46
Filed: 1989-03-10
Granted: 1993-06-09
Abstract: Optically active compounds of formula I <CHEM>  wherein  Y and Z each independently is hydrogen, chlorine or fluorine; W is hydrogen, alkyl, haloalkyl, alkenyl, cycloalkyl, aryl, alkaryl, aralkyl or a group -N=CR<1>R<2> in which R<1> and R<2> each independently is hydrogen, alkyl, aryl, aralkyl, alkaryl or alkenyl, or R<1> and R<2> together form an alkylene group optionally interupted by one or more hetero atoms; and  R is benzoyl, may be prepared by benzoylating a starting compound of formula I, where R is hydrogen and possessing the R-configuration at C<2> , with a benzoylating agent in the presence of a solvent and a tertiary amine.
Patent EP-0344979-B1 (EP)
Inventor: LAFFERTY JOHN JOSEPH
IPC: A61K31/38
Filed: 1989-05-26
Granted: 1994-11-09
Abstract: Alpha-adrenoceptor antagonists having the formula: <CHEM> which are useful to produce  alpha -adrenoceptor antagonism, pharmaceutical compositions including these antagonists, and methods of using these antagonists to produce  alpha -adrenoceptor antagonism in mammals.
Patent EP-0354787-B1 (EP)
Inventor: OKU TERUO
IPC: C07D303/34
Filed: 1989-08-09
Granted: 1995-02-15
Abstract: An oxaspiro[2,5]octane derivative of the formula : <CHEM>  wherein  R<1> is carbamoyl;  lower alkylcarbamoyl;  hydroxy(lower)alkylcarbamoyl;  lower alkoxy(lower)alkylcarbamoyl;  lower alkylthio(lower)alkylcarbamoyl;  lower alkoxycarbonyl(lower)alkylcarbamoyl;  lower alkylcarbamoyloxy(lower)alkylcarbamoyl;  di(lower)alkylcarbamoyl;  N-[hydroxy(lower)alkyl](lower)alkylcarbamoyl; N-[hydroxy(lower)alkyl](lower)alkylcarbamoyloxy(lower)alkylcarbamoyl;  lower alkylcarbamoyloxy(lower)alkenoyl;  N-[heterocycliccarbonyloxy(lower)alkyl](lower)alkylcarbamoyl;  cyclo(lower)alkylcarbamoyl;  arylcarbamoyl;  haloarylcarbamoyl;  protected carbamoyl;  lower alkylthiocarbamoyl;  heterocycliccarbamoyl;  ar(lower)alkenoyl;  lower alkoxycarbonyl; heterocycliccarbonyl which may have lower alkyl, hydroxy, hydroxy(lower)alkyl, lower alkoxy(lower)alkyl or lower alkoxycarbonyl;  lower alkyl;  carboxy(lower)alkyl;  protected carboxy(lower)alkyl;  ar(lower)alkyl which may have halogen or lower alkoxy;  heterocyclic(lower)alkyl;  lower alkylcarbamoyl(lower)alkyl;  hydroxy(lower)alkenoyl;  acyloxy(lower)alkenoyl; or  diacyloxy(lower)alkenoyl;  R<2> is lower alkoxy and <CHEM>  or pharmaceutically acceptable salt thereof. A process for preparing the oxaspiro [2,5] octane derivative is also described, together with a pharmaceutical composition comprising the same as an active ingredient. The compounds exhibit angiogenesis inhibitory activity and are therefore useful in the treatment of, for example, tumours, rheumatoid arthritis, diabetic retinopathy and psoriasis.
Patent EP-0363024-B1 (EP)
Inventor: GARTNER HERBERT ALFONS
IPC: D21H21/10
Filed: 1989-09-11
Granted: 1994-06-29
Abstract: Water-soluble, high molecular weight, linear copolymers of diallyl dimethyl ammonium chloride and acrylamide, are prepared by emulsion copolymerization of a major portion of the acrylamide monomer via stage-addition, and the addition of a chain transfer agent at the conclusion of said copolymerization to prevent branching and cross-linking.
Patent EP-0367596-B1 (EP)
Inventor: COFFMAN ROBERT L
IPC: A61P7/00
Filed: 1989-11-01
Granted: 1993-12-22
Abstract: A method of preventing or reducing eosinophilia associated with certain immune disorders is provided. The method comprises administering an effective amount of an antagonist to human interleukin-5. Preferably, the antagonist is a blocking monoclonal antibody specific for human interleukin-5, or a fragment or binding composition derived therefrom.
Patent EP-0334810-B1 (EP)
IPC: B60B39/00
Filed: 1989-03-15
Granted: 1993-04-21
Abstract: The positioning and attachment of the auxiliary snow-chain device, intended to be arranged under a motor vehicle, is carried out with the aid of suspension locations, preferably three in number (101, 102, 103), which are integrally cast with a cage (1) housing means for driving a swivel arm (3) bearing a small wheel. Each suspension location is made up of a lug provided with a center bore (14) which is traversed by a threaded element having a diameter appreciably less than that of the bore. The top and bottom faces of each lug are rounded. The triangular arrangement of the lugs, which co-operate with components for integration with the vehicle, permits fine positioning at the same time as reliable attachment of the snow-chain device.
Patent EP-0402360-B1 (EP)
Title: Impedance synthesis multiple loop using filtering means
IPC: H04M3/22
Filed: 1988-12-24
Granted: 1993-10-13
Abstract: To supervise a telephone subscriber line (v'2, v'1) and provide it with adjustable AC and DC termination impedances from the exchange (v1, v2), these are supplied by an impedance synthesis multiple loop split into separate DC and AC loop parts by filters at the output of a sense amplifier in the common loop part and fed (e) through a Herter bridge. The amplifier AC output has however to be limited to avoid saturation by a larger DC signal. It now includes a Miller effect integrator output stage (A2) with a low pass frequency response supplying the DC loop and also feeding back an input stage (A1) so that the latter exhibits a high pass frequency response with a DC free output to drive the AC loop and the consequent ability to supply a larger AC output.
Patent EP-0372045-B1 (EP)
Inventor: STROBEL DONALD H
IPC: G08C19/16
Filed: 1989-04-19
Granted: 1996-02-07
Abstract: In a metering pulse generator, a metering element engages a spring member to effect a gradual bending movement in one direction followed by a rapid return movement during which a pulse signal is developed by a piezoelectric material on the spring member . Energy is absorbed during each such rapid return movement of the spring member to provide damping, inhibit oscillations and effect reliable generation of a single pulse signal which is applied to an amplifier for transmission to a monitoring station.
Patent EP-0394384-B1 (EP)
IPC: B01J20/28
Filed: 1989-07-15
Granted: 1993-05-19
Abstract: Dispositif permettant de recevoir des quantités déterminées de produits en vrac et d'en calculer les dimensions, comportant deux voies reliées entre elles et formant un tapis, entre lesquelles sont entreposés les produits en vrac, l'une des voies étant réalisée de manière à former des élévations en forme de coussins réparties sur la surface, ces élévations étant délimitées par des traverses de liaison, disposées longitudinalement et transversalement par rapport à cette voie et entrecroisées et reliées à l'autre voie. Pour réaliser un dispositif du type susmentionné, qui soit simple à construire et à utiliser et qui permette en outre de recevoir de manière durable des quantités déterminées de produits en vrac et de calculer leurs dimensions, il est proposé, dans le cadre de l'invention, que ce dispositif soit constitué de deux tapis (6) décalés de 180 degrés et disposés l'un par rapport à l'autre de telle manière que les élévations (2) en forme de coussins de l'une des voies (1) du premier tapis (6) se prolongent dans les espaces intermédiaires, formés par les traverses de liaison (3), du second tapis (6) et s'y insèrent du fait de leur forme, ces espaces intermédiaires formant des creux (7) correspondant aux élévations (2) en forme de coussins, et que les deux tapis (6) forment ensemble une couche de produits en vrac d'épaisseur uniforme. Les voies (1, 4) des tapis (3) sont constituées de voies en matériaux non tissés, les produits en vrac déposés entre ces voies étant des masses filtrées (5).
Patent EP-0440744-B1 (EP)
Inventor: LEE WEN-HWA
IPC: A61K48/00
Filed: 1989-10-30
Granted: 1997-12-10
Abstract: A method for gene therapy for cancers wherein chromosomal location of an inactive or defective cancer suppressing gene is established, a replacement gene which is preferably cloned is then used to replace the inactive or defective cancer suppressing gene in the chromosome. In addition to its uses in therapy, the present invention provides a means for prophylactically treating individuals having a genetic predisposition to cancer and provides an animal model for testing for carcinogenicity of environmental substances.
Patent EP-0387688-B1 (EP)
Inventor: RAULEDER HARTWIG DR
IPC: C07C41/16
Filed: 1990-03-08
Granted: 1993-12-08
Abstract: Monoalkyl ethers of alkylene glycols and oligoalkylene glycols are reacted completely with (meth)allyl halides or vinyl halides to give terminally monounsaturated glycol ethers as product, wherein initially complete reaction takes place with only one equivalent of alcoholate former, e.g. an alkali metal alcoholate or hydroxide, and two equivalents of glycol monoether, then reaction with one equivalent of alkenyl halide takes place, following which a mixture of product and glycol monoether is filtered off or distilled off from the alkenylmethallyl halide which is formed, then this mixture is reacted with the second equivalent of alcoholate from, whereupon the product is isolated by distillation after addition of a further equivalent of glycol monoether to the residue from the product isolation, and the first and subsequent steps in the reaction are then carried out again.
Patent EP-0392238-B1 (EP)
Inventor: FUCHS KARL-HEINZ
IPC: B65D47/34
Filed: 1990-03-24
Granted: 1995-01-25
Abstract: A dispensing facility (1) to be operated by pressure actuation has on an actuation handle (22) a foaming device (100) which is mounted from outside as an intrinsically enclosed unit by means of a plug-in connection and has in the flow path a foaming body (75) located essentially on the same axis as the dispensing orifice (80). With the aid of two pumps (2,50), to be actuated simultaneously, both a medium and compressed air are forced, after being mixed together, through the foaming body (75) and are foamed until they reach the outlet opening (80) in a final channel (81). As a result, a very good foam quality is achieved with a simple design. <IMAGE>
Patent EP-0388033-B1 (EP)
Title: Spray nozzle for fire control
IPC: A62C31/02
Filed: 1990-02-22
Granted: 1993-05-26
Abstract: A spray nozzle for fire control produces a spray of gas and liquid having an oval transverse cross-section and comprises a mixing chamber having an oval transverse cross-section adapted to induce a toroidal mixing pattern in pressurised gas and liquid introduced to the mixing chamber (6) through a plurality of inlets (10, 8). In a preferred embodiment the mixing chamber (6) is toroidal. The spray nozzle may be used in fire control systems in vehicles or other confined spaces.
Patent EP-0407089-B1 (EP)
IPC: C08L83/12
Filed: 1990-06-27
Granted: 1993-03-10
Abstract: A water-in-silicone oil transparent emulsion is made from a volatile polydimethylsiloxane (1 to 50% by weight), a silicone surfactant (0.1 to 20% by weight), at least one polyhydric alcohol (1 to 50% by weight) and water. The silicone surfactant comprises a polymer of dimethyl polysiloxane with polyoxyethylene and/or polyoxypropylene side chains having a molecular weight of from 10,000 to 50,000 and having the structure: <CHEM>  a having a value of from 9 to 115,  b having a value of from 0 to 50,  x having a value of from 133 to 673, y having a value of from 25 to 0.25.
Patent EP-0508980-B1 (EP)
Inventor: MAKOW DAVID M
IPC: B44F1/10
Filed: 1990-01-02
Granted: 1993-10-20
Abstract: In this invention, animation effects have been obtained in a device containing a light source illuminating a linear polariser (3) producing plane polarised light which is rotated in an electro-optical (2) cell/cells such as a Liquid Crystal or PLZT cell. The angle of the plane is changed at the required speed by a voltage applied to the electrodes (6) of the cell; this voltage being generated in an electronic circuit (8) or obtained from the output of a transducer or a manual voltage controller. The rotated plane polarised light is shining through a stationary set of at least two linear polarisers (1) placed side by side and oriented at different angles and then through a screen containing the art work (7). The emerging lighted image is perceived by the viewer (5) as a change or as an animated movement of the art work. Colour effects can also be obtained when a second electro-optical cell with a chromatic polariser or a chromatic retardation plate is used in a serial arrangement with the above device. In the prior art, the change of the angle of the plane polarised light was achieved by mounting the linear polariser on a mechanically rotated wheel. The introduction of electro-optical voltage controlled cells has many advantages such as in the speed of response, reduction of weight and power consumption, feasibility of new effects, flexibility of design and elimination of moving parts. The applications of this invention are in advertising and exhibition displays, animated signage, animated printed material, instrument readout indicators and monitors, works of art, and in the field of toys and games.
Patent EP-0455668-B1 (EP)
Inventor: BRIDGES IAN GEORGE
IPC: C12N15/29
Filed: 1990-01-26
Granted: 1999-04-14
Abstract: Three similar gene sequences are provided, the sequences being shown in the drawings, which are recovered from male flower parts of maize, specifically anther tissue. When one or more of these sequences are included in a gene construct, expression of an encoded protein is restricted to male parts of the plant. The sequences have utility in any application where expression in male flower parts is indicated, a specific application is in the control of expression of a disrupter protein which imparts male sterility when incorporated in a plant genome.
Patent EP-0454746-B1 (EP)
IPC: F16K31/50
Filed: 1990-01-09
Granted: 1993-07-28
Abstract: PCT No. PCT/EP90/00039 Sec. 371 Date Aug. 29, 1991 Sec. 102(e) Date Aug. 29, 1991 PCT Filed Jan. 9, 1990 PCT Pub. No. WO90/08282 PCT Pub. Date Jul. 26, 1990.A gate valve has a housing for a valve seat, and an attachment which extends outwardly from the housing and constitutes an extension thereof. A cap is secured to the attachment at the end of the latter remote from the housing, and a plate which traverses the attachment is held between the cap and the attachment. An externally threaded, non-rotary valve stem extends between the cap and the housing and passes through the plate. The valve stem meshes with an internally threaded, rotatable sleeve which receives the valve stem and is connected to a handwheel. The sleeve is at least partially confined by the cap and the plate, and both the cap and the plate are provided with bearing locations for the sleeve.
Patent EP-0465547-B1 (EP)
Inventor: JOHANSSON EVALD
IPC: B03C3/68
Filed: 1990-03-20
Granted: 1994-05-18
Abstract: PCT No. PCT/SE90/00174 Sec. 371 Date Aug. 13, 1991 Sec. 102(e) Date Aug. 13, 1991 PCT Filed Mar. 20, 1990 PCT Pub. No. WO90/11132 PCT Pub. Date Oct. 4, 1990.In a method for controlling the current pulse supply to the discharge electrodes of an electrostatic precipitator unit in order to achieve maximum separation of dust from gases conducted between the discharge electrodes and the collecting electrodes of the unit at issue, current pulses (I) with a given pulse current are supplied to the discharge electrodes. The pulse frequency is varied, and instantaneous values (Up, U(I=O), U(I=O+1.6)) corresponding to one another, for the voltage (U) between the discharge electrodes and the collecting electrodes are measured for a number of pulse frequencies. Then, the current pulse supply to the discharge electrodes is set to the pulse frequency at which the highest instantaneous value has been measured.
Patent EP-0422189-B1 (EP)
Inventor: PATEL MANSUKH M
IPC: A23G4/10
Filed: 1990-04-16
Granted: 1996-07-31
Abstract: The use of encapsulated salts to enhance flavor and sweetness characteristics of gum is disclosed. The gum of the present invention comprises gum base, a sweetening and bulking agent, a flavoring agent, and a salt encapsulated in a manner to delay its release from the gum composition during chewing. The encapsulated salt is made by standard coating and encapsulation techniques. The gum is made by standard mixing techniques, though it is preferred to mix the encapsulated salt into the molten gum base.
Patent EP-0476059-B1 (EP)
Inventor: POWELL MICHAEL J
IPC: C12R1/91
Filed: 1990-06-07
Granted: 1996-03-06
Abstract: Antigens capable of eliciting antibodies which can enhance the rate of chemical reactions at peptide bonds are disclosed. In particular, the rate of cleavage or formation of metastable peptide bonds, such as ASN-X, ASP-X, GLN-X, GLU-X, LYS-X, and HIS-Y-X, where X and Y are any amino acid, is enhanced by antibodies elicited by said antigen.
Patent EP-0451277-B1 (EP)
Inventor: SUGAWA KATSUSHI
IPC: H03G3/20
Filed: 1990-07-16
Granted: 1995-06-28
Abstract: An automatic gain control circuit that can be suitably used for communication equipment such as a radio receiver and communication equipment provided with such an automatic gain control circuit. Signals received by an antenna (20) pass through a first band-pass filter (21), an h-f amplifier stage (22), a mixer (24), a second band-pass filter (23) and an i-f amplifier stage (26), and are detected by a detector stage (27). The detected signals are output from an output terminal 28. A gain control voltage VAGC derived at the detector stage (27) from the output of the i-f amplifier stage (26) is fed to the first and second band-pass filters (21, 23) to shift the center frequencies in the passband of these filters from the received frequency by an amount corresponding to the voltage VAGC. Therefore, the gains decrease relative to the received signals in these filters.
Patent EP-0501977-B1 (EP)
Inventor: PRATOLONGO MODESTO
IPC: F16H1/32
Filed: 1990-10-23
Granted: 1995-05-24
Abstract: The device comprises a driving hub (4, 18) coaxially connected to one shaft (20) and oscillatably engaging a number of planetary gear elements (8, 25) homogeneously distributed around the axis of said hub. The planetary gear elements (8, 25) are engaged between a driven crown wheel (6, 21) which is coaxially fastened to a second shaft (3, 23) and an intermediate crown wheel (7, 24) oscillatably linked to the driven crown wheel (6, 21). The planetary gear elements (8, 25) driven in rotation by the hub (4, 18), are guided by the driven crown wheel (6, 21) and the intermediate crown wheel (7, 24) according to an elliptic path submitting them to a cyclic reciprocating movement relative to the axis of the driving hub (4, 18). An actuator (12, 35) tends to cause the driven crown wheel (6, 21) and intermediate crown wheel (7, 24) to rotate in opposite ways in view of transmitting resultant forces counteracting their being driven by the hub (4, 18) to the planetary gear elements (8, 25).
Patent EP-0500623-B1 (EP)
Inventor: WIEHN HELMUT
IPC: C08L97/02
Filed: 1990-11-05
Granted: 1994-04-13
Abstract: In the manufacture of synthetic foams and also especially in that of timber materials using urea-formaldehyde condensate binders, the mol ratio between urea and formaldehyde is decisive for the resultant final rigidity and the presence of free gaseous formaldehyde. In order, with a favourable mol ratio, to reduce the quantity of gaseous formaldehyde remaining in the timber material and at the same time to obtain effective fire resistance in both synthetic foams and timber materials adhesively secured with isocyanate, the invention proposes a combination of effective substances to be added to the initial raw materials as a granulate with a grain size of 80 to 1,500 my.
Patent EP-0485609-B1 (EP)
Inventor: KUME HIROSHI
IPC: G02F1/09
Filed: 1990-11-13
Granted: 1996-01-31
Abstract: An optical isolator comprising a polarizer, an analyzer, a Faraday rotor and a permanent magnet for magnetizing the Faraday rotor and inducing a Faraday effect. Degradation of isolation characteristics occurs near a critical temperature (0 °C or 70 °C) of a practical temperature range of from about 0 to 70 °C if adjustment and assembly are made in such a manner that maximum isolation is accomplished at the ambient temperature and for the wavelength used for the assembly. Therefore, the temperature position of maximum isolation is controlled by assembling the isolator at room temperature and for a wavelength which is shifted by a very small wavelength Δμ from the wavelength μ used so that maximum isolation can be obtained at an arbitrary use temperature by utilizing temperature dependence of the Faraday rotor.
Patent EP-0502223-B1 (EP)
Inventor: KOENIG ELMAR
IPC: A47C27/14
Filed: 1991-03-05
Granted: 1994-06-01
Abstract: The invention achieves this object by a two-part upholstered body (mattress 1) consisting of a soft elastic foam material whose parts (2 and 3) have a different compression hardness. The mutually facing surfaces have a sinusoidal profile (4) whose frequency (f) and amplitude (a) are variable. As a result, hard and soft zones can be formed in a targeted manner. <IMAGE>
Patent EP-0453773-B1 (EP)
Inventor: WACK HELMUT
IPC: E04G23/08
Filed: 1991-03-22
Granted: 1994-09-28
Abstract: A wrecking device for wrecking and comminuting, in particular, reinforced concrete consists of two hydraulically driven jaws (7, 8) cooperating in the manner of shears, of which one has at least two and the other at least three working strips (15-21) equipped with breaking teeth, said working strips all being arranged parallel next to one another and interlocking alternately with one another in the closed position. For efficient comminution of concrete, provision is made, in the jaw (8) with the largest number of working strips, for the two outer working strips (18, 21) to lie in a common plane perpendicularly to the closing movement, whereas the intermediate working strips (19, 20) are set back with respect to the closing movement. Furthermore, the reinforcement can be removed from reinforced concrete without problems and in the same working stroke by the fact that on the sides, facing one another in the closed position, of at least two adjacent working strips (16, 19) of the two jaws (7, 8), there are arranged between the breaking teeth (22, 23) cutting tools (31, 32) which are set back relative to the breaking teeth in the direction of the closing movement and move past one another in a shearing manner towards the end of the closing movement. 
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Patent EP-0469327-B1 (EP)
Inventor: TANIGUCHI NORIO C O MITSUI PET
IPC: B01J23/44
Filed: 1991-07-04
Granted: 1995-10-25
Abstract: In a process for producing purified terephthalic acid which comprises catalytically oxidizing p-xylene in liquid phase to produce crude terephthalic acid containing 4-carboxybenzaldehyde as a main impurity therein, and treating the crude terephthalic acid with hydrogen in the presence of a hydrogenation catalyst in a reaction vessel, thereby to produce purified terephthalic acid containing 4-carboxybenzaldehyde in an amount of fixed range in a stationary manner, there is provided an improvement which makes it possible for the treatment to reach the stationary state promtly after partial exchange of deactivated catalyst for a new one. The improvement comprises feeding into the reactor crude terephthalic acid which contains 4-carboxybenzaldehyde in an amount larger than that in the stationary state of the treatment, and treating the terephthalic acid until the treatment reaches the stationary state.
Patent EP-0467189-B1 (EP)
Inventor: SOTIRIU KORNELIUS DIPL-ING
IPC: F25D17/02
Filed: 1991-07-08
Granted: 1995-02-08
Abstract: The invention relates to a cold water unit with performance adjustment to the heat generation of objects to be cooled with constant cold water forward run temperature, in which there is in the cold water foward run circuit a heat exchanger which is flowed through by coolant and which compensates the difference between cooling output and thermal output to be led away. Known cold water units are at the same time of very great constructional outlay. This outlay is reduced by the present invention in that the condenser (2K) of the cold water unit is at the same time that part of the heat exchanger (2W), present for regulation of the water temperature of the cooling water, which is flowed through by the cooling agent. <IMAGE>