baber/WOPTO huggingface dataset:
Patent WO-2019191563-A1 (WO)
Title: Treatment of autoimmune and inflammatory disorders using antibodies that bind interleukin-17a (il-17a)
Inventor: CALZONE FRANK J
IPC: A61P43/00
Filed: 2019-03-29
Abstract: This application provides, inter alia, antibodies or antigen-binding fragments thereof, targeting IL-17A expressed on injured tissues associated with multiple diseases. These anti-IL- 17A antibodies, or antigen-binding fragments thereof, have a high affinity for IL-17A and function to inhibit IL-17A. The antibodies and antigen-binding fragments are useful for treatment of human diseases, infections, and other conditions that can be treated by inhibiting IL-17A mediated activity.
Patent WO-2019195659-A1 (WO)
Title: Cellular compositions derived from prior organ donors and methods of manufacture and use thereof
Inventor: DEITCHER STEVEN
IPC: C12N5/0789
Filed: 2019-04-05
Abstract: The invention provides compositions for establishing mixed chimerism in a subject. The compositions include CD34 +  cells and CD3 +  cells derived from an apheresis product obtained from a subject that has previously donated a solid organ. The invention also provides methods of making and using such compositions.
Patent WO-2019199843-A1 (WO)
Title: Ranking property listing search results
Inventor: XU TAO
IPC: G06Q10/00
Filed: 2019-04-09
Abstract: An online reservation system (15) is configured to receive requests from a guest for searching property listings (77) and to return property listings that satisfy the search criteria of the requests. The online reservation system uses a machine learning algorithm to rank the property listings returned by the search. The reservation system uses objective functions to determine parameters for each property listing and assign a ranking based on the parameters. A first objective function generates a parameter indicating an extent to which a property listing matches preferences of the guest, and is based on data about the guest's interactions with the reservation system. A second objective function generates another parameter indicating an extent to which the search request matches the preferences of the host associate with the property listing, and is based on data about the host's responses to reservation requests.
Patent WO-2019200148-A1 (WO)
Title: Systems and methods for registration and activation of temperature-sensing garments
Inventor: SHEN XUENING
IPC: A61B5/00
Filed: 2019-04-11
Abstract: A system for monitoring a patient includes a garment including a controller and one or more temperature sensors, and a receiving station configured to communicate with the garment over a wireless communication network. The garment may be operable in an inactive mode in which the controller samples the temperature sensors to generate a first set of temperature measurements, and an active mode in which the controller samples the temperature sensors to generate a second set of temperature measurements and the garment communicates the second set of temperature measurements to the receiving station, where the controller transitions the garment from the inactive mode to the active mode based at least in part on the first set of temperature measurements and/or other sensor data such as garment motion data and/or garment orientation data.
Patent WO-2019204417-A1 (WO)
Title: Obtaining cellular and dna material from human female reproductive system for various purposes including ovarian and endometrial cancer detection
Inventor: TEVLIN MAYA
IPC: G01N33/574
Filed: 2019-04-17
Abstract: Efficient harvesting of cells and DNA material from female reproductive system is made possible by processing gelatinous part of cervical mucus. Rinsing may be used to separate the gelatinous part of cervical mucus from the bulk of cervical cells. The harvested cells and DNA material may be used for diagnostic purposes including ovarian and endometrial cancer detection.
Patent WO-2019204467-A1 (WO)
Title: Autonomous optimization of intra-train communication network
Inventor: MANSFIELD EDWARD
IPC: B61L23/34
Filed: 2019-04-17
Abstract: A system for dynamically adjusting a configuration of an intra-train communication network includes an electronic device and a computer-readable storage medium. The computer- readable storage medium has one or more programming instructions that, when executed, cause the electronic device to receive one or more parameters values associated with a train consist, determine whether a potentially adverse condition that would affect intra-train communication for the train consist is anticipated based on at least a portion of the received parameters, in response to determining that the potentially adverse condition is anticipated, identify one or more updated network parameter settings that will assist in maintaining intra-train communication of the train consist during an occurrence of the potentially adverse condition by executing a machine learning model, and implement the identified one or more updated network parameter settings.
Patent WO-2019204546-A1 (WO)
Title: Device or method for cleaning spray equipment and a system retrofitted therewith
Inventor: MURRAY THOMAS
IPC: B05B15/555
Filed: 2019-04-18
Abstract: A cleaning device for use with an atomizer that applies paint to the surface of a component in a spray booth includes an external and internal surface in which a least a portion of one or more of the surfaces are coated with a conductive coating. This conductive coating comprises one or more fluoropolymers and may be static dissipative. The cleaning device further includes an exit port that has an aperture between about 2.54 - 7.62 cm located in the shroud of the device opposite the opening that receives the atomizer and near a bottom corner of the shroud. A kit used to retrofit existing paint spraying systems includes a fully assembled cleaning device and optionally, a regulator assembly capable of reducing the pressure of a cleaning fluid to about 80 psi. During installation, the regulator assembly is mounted external to the spray booth.
Patent WO-2019217140-A1 (WO)
Title: Immersive web-based simulator for digital assistant-based applications
Inventor: ZHANG XIONGQI
IPC: G06F11/36
Filed: 2019-04-30
Abstract: Immersive web-based simulator for digital assistant-based applications is provided. A system can provide, for display in a web browser, an inner iframe configured to load, in a secure, access restricted computing environment, an application configured to integrate with a digital assistant. The application can be provided by a third-party developer device. The system can provide, for display in a web browser, an outer iframe configured with a two-way communication protocol to communicate with the inner iframe. The system can provide a state machine to identify a current state of the application loaded in the inner frame, and load a next state of the application responsive to a control input.
Patent WO-2019241315-A1 (WO)
Title: Pde5 derived regulatory constructs and methods of use in immunotherapy
Inventor: SURI VIPIN
IPC: C12N15/12
Filed: 2019-06-12
Abstract: The present disclosure relates to tunable biocircuit systems for the development of controlled and/or regulated therapeutic systems. In particular, regulatable biocircuits containing destabilizing domains (DD) derived from mutant human cGMP-specific phosphodiesterase type 5 (PDE5) are disclosed. Especially, the present disclosure provides an effector module. Such effector module may include (a) a stimulus response element (SRE), wherein the SRE is a DD, said DD comprising at least one mutation relative to cGMP-specific 3',5'-cyclic phosphodiesterase (hPDE5; SEQ IID NO: 1) and (b) at least one payload, which is attached, appended or associated with sai SRE. The SRE may be responsive to one or more stimuli.
Patent WO-2019245977-A1 (WO)
Title: Toner avec dispersion de cire contrôlée
Inventor: HOLLOWAY ANN
IPC: G03G9/097
Filed: 2019-06-17
Abstract: L'invention concerne une composition de toner comprenant des résines de polyester de poids moléculaire faible et élevé. Elle comprend également un agent de libération, tel qu'une cire de polyoléfine, et un copolymère triséquencé ayant une structure de forme A-b-B-b-A, dans laquelle A est un bloc dur et B est un bloc souple. Le bloc dur est du styrène, tandis que le bloc souple est du butadiène/butylène. Lors d'une hydrogénation partielle, le copolymère permet d'améliorer la dispersion, la commande de mobilité et la taille de domaine de l'agent de libération.
Patent WO-2019246009-A1 (WO)
Inventor: DORBAN ANDREW MICHAEL
IPC: E21B34/00
Filed: 2019-06-18
Abstract: A downhole completion system and methodology is provided for use in a well. The downhole completion comprises a packer and a plurality of flow control sand screens. Each flow control sand screen has an inflow control device (ICD). The downhole completion further comprises at least one lower sand screen positioned below the plurality of flow control sand screens. The at least one lower sand screen is configured without an ICD. A flow restrictor is disposed between the plurality of flow control sand screens and the at least one lower sand screen.
Patent WO-2019246030-A1 (WO)
Inventor: CATE JAMES H DOUDNA
IPC: C12N15/81
Filed: 2019-06-18
Abstract: Engineered stable mating-competent Kluyveromyces yeast comprise inactivated  KAT1  and  ALPHA3  transposase genes, rendering the strain unable to switch mating types and unable to perform self-mating.
Patent WO-2020018235-A1 (WO)
Title: Beam-specific timing advance for timing response transmission for round-trip-time estimation
Inventor: SADIQ BILAL
IPC: H04W56/00
Filed: 2019-06-21
Abstract: Disclosed are techniques for determining a beam-specific timing advance for Round-Trip Time (RTT) estimation. In an aspect, a first node receives a plurality of beams transmitted by a second node on a wireless channel, selects a first beam from the plurality of beams for transmitting a timing response, determines a timing statistic, a timing difference, and a timing advance for the first beam, wherein the timing difference comprises a difference between the timing statistic and an earliest time of arrival of the plurality of beams, and wherein the timing advance comprises a multiple of the timing difference, and transmits the timing response for the first beam to the second node on the wireless channel, wherein the first node transmits the timing response after a time delay from the timing statistic of the first beam, wherein the time delay comprises a difference between a predetermined time delay and the timing advance.
Patent WO-2020014208-A1 (WO)
Title: Camk4 inhibitors for restoration of podocyte function in kidney disease
Inventor: FAHMY TAREK
IPC: A61P13/12
Filed: 2019-07-09
Abstract: A method of treatment and compositions for use therein are based on the discovery of how to stop immune complexes from forming and for reducing existing complexes in renal disease and how to restore podocyte function generally in kidney disease. In one embodiment, the method of treatment involves targeted delivery of Calcium/Calmodulin-dependent kinase 4 inhibitor to the kidney for treatment of patients with kidney pathologies and for replacement or augmentation of kidney dialysis. The studies demonstrate that CaMK4 is pivotal in immune and non-immune podocyte injury and that its targeted cell specific inhibition preserves podocyte structure and function, and is therefore effective in the treatment and even reversal of podocytopathies in autoimmune kidney disease such as SLE glomerulonephropathy and non-autoimmune kidney disease including focal segmental glomerulosclerosis.
Patent WO-2020033115-A1 (WO)
Title: Isolating a redirected biometric device to a remote session
Inventor: VAJRAVEL GOKUL THIRUCHENGODE
IPC: H04L29/06
Filed: 2019-07-17
Abstract: A redirected biometric device can be isolated to a remote session. Such session level restrictions can be implemented using a filter driver that is layered on top of the device driver stack for the redirected biometric device. When a biometric device is redirected by a user to a remote session, the filter driver can obtain an identifier of the biometric device and maintain a mapping between the identifier and the session ID of the redirecting user's remote session. Then, when an application executing on the server attempts to enumerate biometric devices, a hooking component can inspect and modify the corresponding response to remove any biometric devices that are not redirected to the same user session in which the application is executing. In this way, the application will not be able to discover any biometric devices that are redirected to other user sessions.
Patent WO-2020023537-A1 (WO)
Title: Derivatives of papaverine that are effective hypoxic tumor radiosensitizers
Inventor: DENKO NICHOLAS
IPC: A61K31/472
Filed: 2019-07-23
Abstract: Disclosed herein are compounds, compositions, and methods for inhibiting mitochondrial oxygen consumption in a cancerous tissue. The compounds, compositions, and methods can be used to treat a subject with hypoxic cancerous tissue.
Patent WO-2020028515-A1 (WO)
Title: Neuroprotective disruption of kv2.1/syntaxin interaction by small molecules
Inventor: AIZENMAN ELIAS
IPC: A61K31/16
Filed: 2019-07-31
Abstract: Disclosed herein are small molecule compounds capable of disrupting Kv2.1-syntaxin binding. The compounds are useful for treating a variety of neurological disorders, diseases, and injuries.
Patent WO-2020028552-A1 (WO)
Inventor: KERR WILLIAM
IPC: A61K31/565
Filed: 2019-07-31
Abstract: La présente invention concerne des procédés d'utilisation de compositions qui inhibent les inositol 5'-phosphatases contenant le domaine SH2 (SHIP) pour activer des cellules microgliales, ainsi que des procédés d'utilisation de telles compositions pour le traitement ou l'atténuation de troubles neurodégénératifs chez un sujet.
Patent WO-2020037098-A1 (WO)
Title: Novel organoleptic compounds
Inventor: VELIATH ELIZABETH D
IPC: C07C31/13
Filed: 2019-08-15
Abstract: The present invention relates to novel ((4,4,8-trimethyltricyclo[6.3.1.0 2,5 ]dodecan-1-yl)oxy) alcohols and their use as fragrance materials.
Patent WO-2020076446-A1 (WO)
Inventor: ZHOU YAN
IPC: H04B7/0404
Filed: 2019-09-06
Abstract: Aspects described herein relate to configuring active spatial relations in wireless communications. A capability indicating a number of active spatial relations supported for detecting downlink reference signals or generating uplink beams can be indicated to an access point. A configuration of spatial relations indicating a transmit filter of reference signals for use in transmitting uplink communications can be received from the access point and based on the capability. One or more of the reference signals received from the access point can be detected based on the configuration.
Patent WO-2020056390-A1 (WO)
Title: Bit-level data generation and artificial intelligence techniques and architectures for data protection
Inventor: OETKEN GARRETT
IPC: G06F11/00
Filed: 2019-09-13
Abstract: Techniques and architectures for representing data with one or more n-dimensional representations and/or using one or more models to identify threats associated with the one or more n-dimensional representations are described herein. For example, the techniques and architectures may determine one or more coordinates for one or more points based on one or more sets of bits in the data and generate an n-dimensional representation for the data based on the one or more points. The techniques and architectures may evaluate the n-dimensional representation with one or more machine-trained models to detect a threat associated with the data, such as malware or another threat.
Patent WO-2020076473-A1 (WO)
Inventor: PRYOR GLEN F
IPC: B65H23/00
Filed: 2019-09-19
Abstract: A cartridge for a food processing machine includes a base member, a stock roller drag brake, a nip roller, and a chute. The stock roller drag brake is rotatably attached to the base member. The nip roller is rotatably attached to the base member. The chute is attached to the base member.
Patent WO-2020076841-A1 (WO)
Inventor: LAGHATE MIHIR VIJAY
IPC: H04W72/12
Filed: 2019-10-08
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may determine, for a candidate UE uplink beam, a transmit power due to a maximum permissible exposure (MPE) constraint; estimate, for the candidate UE uplink beam, a receive power for a base station based at least in part on the transmit power due to the MPE constraint; determine a target receive power for the base station; and select the candidate UE uplink beam as an active UE uplink beam based at least in part on the estimated receive power for the base station and the target receive power for the base station. Numerous other aspects are provided.
Patent WO-2020081559-A1 (WO)
Inventor: STRASSER JOSEPH S
IPC: C21B13/12
Filed: 2019-10-15
Abstract: La présente invention concerne un procédé de refroidissement d'électrodes de four au moyen d'un liquide de refroidissement contenant des tensioactifs. Ce procédé peut être appliqué à des électrodes utilisées dans des fours à arc électrique et des fours de métallurgie à poche. Le procédé peut mettre en œuvre la pulvérisation du liquide de refroidissement sur l'électrode, de façon à abaisser la température de l'électrode et réduire la consommation d'électrode.
Patent WO-2020092173-A1 (WO)
Inventor: LIAO CHING-YU
IPC: H04W28/08
Filed: 2019-10-25
Abstract: L'invention concerne des systèmes et des procédés pour gérer un trafic accédant au service d'un réseau mobile terrestre public (PLMN) au niveau d'un réseau non public afin d'exécuter une dérivation locale pour un trafic sélectionné.
Patent WO-2020101866-A1 (WO)
Title: Double wing aircraft
Inventor: DIZDAREVIC FARUK
IPC: B64C39/08
Filed: 2019-10-28
Abstract: The present invention is a double wing aircraft with two fixed wings embodied as either a flying wing configuration or a double wing configuration having a fuselage with smaller external dimensions, larger airlifting area, thinner airfoils, and lighter airframe relative to prior art that altogether is resulting with lower drag, fuel consumption, harmful emissions, and noise, as well as higher speed, maneuverability, and flight safety, longer range, and shorter runway when compared to prior art.
Patent WO-2020112849-A1 (WO)
Inventor: RIEGER CRAIG G
IPC: G06F21/00
Filed: 2019-11-26
Abstract: A resilient security agent determines a cyber and/or physical health of a control system by, inter alia, communicating cyber-physical key data through cyber-physical control paths of the system, and determining error introduced by the communication. The resilient security agent may be further configured to verify the integrity of acquired cyber-physical state information. The cyber health of the control system may be evaluated by comparing the acquired cyber state information to one or more cyber state profiles. The physical health of the control system may be evaluated by comparing the acquired physical state information to one or more physical state profiles.
Patent WO-2021126153-A1 (WO)
Title: Three-dimensional printed polymer objects
Inventor: NAUKA KRZYSZTOF
IPC: B82Y30/00
Filed: 2019-12-16
Abstract: A three-dimensional (3D) printed object is described. The 3D printed object comprises a polymer. A surface of the 3D printed object comprises the polymer 5 and a UV absorbing colorant. The surface has a surface area roughness Sa (arithmetical mean height) of ≤5.0 μm. A method for preparing a three dimensional (3D) printed object having a smooth surface is also described.
Patent WO-2020139871-A1 (WO)
Title: Synthèse de novo polynucléotidique hautement précise
Inventor: PECK BILL JAMES
IPC: C07H21/02
Filed: 2019-12-23
Abstract: L'invention concerne des procédés, des systèmes, des compositions et des dispositifs destinés à la préparation de blocs de constructions de haute qualité, tels que des polynucléotides. Les procédés décrits dans la présente invention permettent un lavage efficace de réactifs, de solvants ou de sous-produits résiduels à partir d'étapes synthétiques précédentes pour permettre la génération de polynucléotides à faibles taux d'erreur. Les procédés décrits dans la présente invention permettent également de réduire les taux de suppression pendant la synthèse chimique d'acides nucléiques. En outre, les procédés et les dispositifs décrits dans la présente invention permettent la construction rapide et l'assemblage de grandes banques de polynucléotides hautement précis.
Patent WO-2020142432-A1 (WO)
Inventor: DUONG VAN
IPC: F16J15/3208
Filed: 2019-12-30
Abstract: A seal comprising: an annular body defining an inner sidewall and an outer sidewall extending from a base; and a plurality of energizing elements disposed within a recess between the inner and outer sidewalls, wherein at least two adjacent energizing elements of the plurality of energizing elements have different unit loads as compared to one another, and wherein the at least two adjacent energizing elements contact the inner sidewall.
Patent WO-2021150241-A1 (WO)
Inventor: BODEMANN SCOTT
IPC: F17C7/04
Filed: 2020-01-24
Abstract: L'invention concerne un système qui comprend un premier chemin d'écoulement conçu pour permettre un écoulement continu de gaz, le premier chemin d'écoulement comprenant une première pression, un module d'obstruction; et un mécanisme de sollicitation conçu pour positionner le module d'obstruction à l'intérieur du chemin d'écoulement afin de limiter mécaniquement l'écoulement traversant en réponse physique à la première pression incidente sur le mécanisme de sollicitation.
Patent WO-2020160077-A1 (WO)
Title: Échafaudages de tissus mous composites entièrement polymères biorésorbables imprimés en 3d
Inventor: AKAR BANU
IPC: A61L24/00
Filed: 2020-01-29
Abstract: L'invention concerne des encres photoréactives, des matériaux et des objets thermodurcissables (par exemple, des implants médicaux, des échafaudages, des dispositifs, etc.) fabriqués à partir de celles-ci, et des procédés de préparation et d'utilisation de ceux-ci.
Patent WO-2020160435-A1 (WO)
Inventor: CARCANO MARCO
IPC: H05B6/64
Filed: 2020-01-31
Abstract: La présente invention concerne un four pouvant comprendre un compartiment de cuisson conçu pour recevoir un produit alimentaire, au moins une paire de supports de grille disposés au niveau de parois latérales opposées de la chambre de cuisson, une grille conçue pour supporter le produit alimentaire suite à la mise en place de la grille sur les supports de grille, un ensemble isolant formant interface de grille comprenant un matériau isolant fournissant une barrière diélectrique entre la grille et les supports de grille, et un système de chauffage radiofréquence (RF) conçu pour fournir de l'énergie RF dans le compartiment de cuisson à l'aide de composants électroniques à l'état solide afin de chauffer le produit alimentaire. Les composants électroniques à l'état solide comprennent une électronique d'amplificateur de puissance et une électronique de commande conçue pour commander le fonctionnement de l'électronique d'amplificateur de puissance.
Patent WO-2020163756-A1 (WO)
Inventor: VERSTRAETE MARTHIJS
IPC: B01D46/52
Filed: 2020-02-07
Abstract: An air cleaner assembly includes a housing and a removable cover. A filter element is removably positioned in the housing. A two-part mating catch assembly includes a first part that is secured to the cover and a second part that is on one of the housing and the filter element. The first part and second part are positioned to releasably mate when the filter element is operably mounted within the housing.