baber/WOPTO huggingface dataset:
Patent DE-69033179-D1 (DE)
Inventor: DALE JAMES
IPC: C12Q1/6813
Filed: 1990-02-13
Granted: 1999-07-29
Abstract: A method for detecting a specific polynucleotide sequence in a material is disclosed. The method includes exposing said material to an oligonucleotide primer having a sequence complementary to part of said specific polynucleotide sequence wherein said primer binds to part of said polynucleotide sequence when present in said material. Primer bound to the polynucleotide sequence is extended wherein any extended primer includes a detectable element and/or a separation element. Any extended primer is then separated into a fraction wherein said fraction does not have detectable element not included in said extended primer. One then determines whether any extended primer is present in said fraction by assaying said fraction for said extended primer wherein the presence of said extended primer is indicative of the presence of the specific polynucleotide sequence in said material and the absence of said extended primer in said fraction is indicative of the absence of the specific polynucleotide sequence in said material.
Patent DE-69101378-D1 (DE)
Inventor: JORGENSEN ANKER STEEN
IPC: C07C323/12
Filed: 1991-04-23
Granted: 1994-04-14
Abstract: Novel [1]benzothieno[2,3-b]pyrazine-2,3(1H,4H)-diones or tautomeric forms thereof of the general formula (I)   <IMAGE> (I)  wherein R1, R2, R3 and R4 independently represent hydrogen, halogen, alkyl, alkoxy or trifluoromethyl. The compounds are useful for treating a central nervous system ailment associated with the NMDA receptor-associated glycine site.
Patent DE-69107057-D1 (DE)
Inventor: SORIANO LOUIS
IPC: H01B13/012
Filed: 1991-11-14
Granted: 1995-03-09
Abstract: PCT No. PCT/FR91/00896 Sec. 371 Date Sep. 15, 1992 Sec. 102(e) Date Sep. 15, 1992 PCT Filed Nov. 14, 1991 PCT Pub. No. WO92/10013 PCT Pub. Date Jun. 11, 1992.A device for manufacturing electrical wiring looms comprises temporary holding clips (11) for the wire ends with a high holding capacity, located on the linear conveyor between the transfer clips and an insertion station. The temporary holding clips comprise a base (14) carrying the clip body (15) which has recesses (16) separated by walls (17). The walls have at least one retaining lip (21) extending substantially along the opening (16A) of recesses (16). The flexible tubing (18) with predetermined length can be flattened and inserted into the recesses.
Patent DE-69108368-D1 (DE)
Inventor: EPEMA S
IPC: E05F15/56
Filed: 1991-12-24
Granted: 1995-04-27
Abstract: A door system of the swivel-sliding type for use in a vehicle, suitable in particular for a vehicle for public transport, said door system comprising at least one door panel; suspension means for said at least one door panel, which comprise a telescopic guide (5); and a drive system for said at least one door panel, wherein the drive system comprises at least one piston-cylinder assembly (29,30) of which a first movable part (29) is connected to the telescopic guide via a system of arms and rods so as to cause said telescopic guide in operation to perform a plugging movement, while a second part (30) of the piston-cylinder assembly is provided with a projection extending into a track (32) having a first section extending substantially transverse to said at least one door panel and an adjoining section extending substantially parallel to the telescopic guide, the projection forming a part of a pantograph construction mounted between a fixed pivot point and a point of atttachment on said door panel, said pantograph construction (33) transmitting the movement of the projection to the door. <IMAGE>
Patent DE-69114815-D1 (DE)
Inventor: HUERLIMANN KURT
IPC: E06B3/54
Filed: 1991-09-27
Granted: 1996-01-04
Abstract: The frame is formed from two profiles (1; 20) provided with means of being assembled by snap-fitting alone. One of the profiles (20) forms a rim (14) ensuring the holding of the panel (18). The first profile (1) is arranged to be fixed or to be supported by a wall or by a suitable chassis. <IMAGE>
Patent DE-69126446-D1 (DE)
Inventor: TAKASE AKIRA
IPC: C07C251/48
Filed: 1991-07-24
Granted: 1997-07-10
Abstract: A process for producing a E-isomer of the formula:wherein X is hydrogen, C<sub>1</sub>-C<sub>6</sub> alkyl, C<sub>1</sub>-C<sub>6</sub> alkoxy or halogen; A is -CONHCH<sub>3</sub> or -COOR; and R is C<sub>1</sub>-C<sub>6</sub> alkyl comprises reacting a Z-isomer of the formula [VI]:wherein X, A and R are as defined above, with an acid in a C<sub>1</sub>-C<sub>6</sub> alcohol.
Patent DE-69131979-D1 (DE)
Inventor: KIEFER C
IPC: C07K16/18
Filed: 1991-08-28
Granted: 2000-03-16
Abstract: A purified binding protein selected from the group consisting of insulin-like growth factor binding protein having an amino acid sequence which is at least 85% homologous to the amino acid sequence of FIG. 1 and fragments thereof comprising at least 10 consecutive amino acids of the sequence that are capable of binding to an antibody specific for the protein or to an insulin-like growth factor is described. Recombinant DNA molecules encoding the binding proteins and subsequences thereof are also described along with recombinant microorganisms and cell lines containing the DNA molecules and methods for preparing the binding proteins by growing the recombinant hosts containing the relevant DNA molecules. Antibodies to the protein, identified as IGFBP-6, which are useful in various diagnostic applications, are also described.
Patent DE-69201061-D1 (DE)
Inventor: KENWORTHY DAVID MICHAEL ANTHON
IPC: B29C65/34
Filed: 1992-01-29
Granted: 1995-02-16
Abstract: A closure for sealing the cutter guide tube of a pipe saddle fitting comprises a cap of thermoplastic material having a screw-threaded section (5) to enable releasable attachment of the closure to the tube, and a section (6) with a cylindrical surface incorporating a heating coil (8) to which a welding current is delivered to fix the closure permanently to the tube when the pipe joint has been completed and tested. <IMAGE>
Patent DE-69207571-D1 (DE)
Inventor: CEVASCO ALBERT A
IPC: C07C69/657
Filed: 1992-11-23
Granted: 1996-02-22
Abstract: There is provided a method of manufacture of dialkyl monohalomaleate and dialkyl monohalofumarate and mixtures thereof via a dehydrohalogenation of the appropriate dialkyl dihalosuccinate precursor in the presence of an aqueous base and a phase transfer catalyst.
Patent DE-69207863-D1 (DE)
Inventor: CHOPRA SHAM KUMAR
IPC: A61K31/405
Filed: 1992-11-10
Granted: 1996-03-07
Abstract: The invention relates to a device for the release of at least one active substance (e.g. ranitidine) into a fluid medium by dissolution comprising a covering, which is impermeable to the active substance and the fluid, having at least one aperture therein and defining a shaped cavity, the cavity being filled by a shaped core comprising the active substance, and wherein:   a) on exposure of the device to the fluid medium, a surface of the core is exposed and dissolution of the surface by the fluid medium causes a change in at least one dimension of the area of the surface, whilst the surface area of the exposed surface remains substantially constant over at least 50% of the total dissolution time of the core; or b) the active substance is disposed in a matrix of an inert insoluble excipient, the device being axially symmetrical, with its aperture being peripherally disposed so that the release surface of core which is exposed through the aperture is substantially cylindrical or part of a cylinder in shape, whereby to allow substantially constant release of the active substance over at least part of the dissolution time; and processes for its preparation.   <IMAGE>
Patent DE-69213227-D1 (DE)
Inventor: ELLENBERGER PETER
IPC: C08G59/44
Filed: 1992-02-14
Granted: 1996-10-02
Abstract: A storable cement-mortar dry mix, which comprises the components cement, aggregate, reaction resin and hardener in a single mixture, wherein the hardener is present as the reaction product of the hardener with an organic acid or a functional derivative thereof.
Patent DE-69215685-D1 (DE)
Inventor: DELALLE JACQUES
IPC: H01R4/22
Filed: 1992-09-03
Granted: 1997-01-16
Abstract: PCT No. PCT/GB92/01606 Sec. 371 Date Feb. 14, 1994 Sec. 102(e) Date Feb. 14, 1994 PCT Filed Sep. 3, 1992 PCT Pub. No. WO93/05546 PCT Pub. Date Mar. 18, 1993.An electrical terminal (1) for connection to one or more electrical wires comprises a conventional terminal portion (2) having a lug portion (3) and a hollow shank (4), a jacket (11) of polymeric insulation that extends over the shank, and a tapering hollow connection piece (6) for example in the form of a coiled wire. The tapering connection piece has an internal and external screw thread and is arranged partly within the end of the shank. It is capable of receiving one or more electrical wires so that they can be secured within the connection piece (6), and the connection piece (6) can be secured within the shank (5) by twisting the terminal about the wires. The jacket (11) is preferably formed from a heat-shrinkable sleeve, and the terminal preferably includes a quantity of solder (9) for forming a permanent electrical connection.
Patent DE-69219098-D1 (DE)
Inventor: SOLDI LIBORIO
IPC: F16K47/02
Filed: 1992-12-09
Granted: 1997-05-22
Abstract: The present invention relates to an anti-hammering sealing element for ceramics cartridges and discs,for mixing cocks or faucets and the like, characterized in that it comprises,on the fixed ceramics disc,at at least some ports for the inlet of cold and warm water,a protecting tubular portion,made of a comparatively rigid plastic material,which houses in its inside a gasket made of a material having a comparatively small stiffness. <IMAGE>
Patent DE-69219576-D1 (DE)
Inventor: OMETTO WALTER
IPC: B65D77/20
Filed: 1992-12-17
Granted: 1997-06-12
Abstract: The container (1) has a peel-off lid (2) heat-welded thereto. The weld includes an anchorage region (3), whereby the container (1) can be opened by peeling back the lid (2) and the lid (2) remains attached to the container (1) at the anchorage region (3). The anchorage region (3) includes an arcuate portion (4) having a spot-weld (5,6) at each end. <IMAGE>
Patent DE-69227081-D1 (DE)
Inventor: OHNOTA MICHIRO
IPC: A61K31/425
Filed: 1992-02-24
Granted: 1998-10-29
Abstract: A novel thiazolidine-2,4-dione derivative with hypoglycemic and aldose reductase inhibitory activities, represented by general formula (1), a salt thereof, a process for producing the same, and a pharmaceutical containing the same, wherein R<1> and R<2> may be the same or different from each other and each represents hydrogen, halogen, lower alkyl, hydroxy, lower alkoxy, nitro or amino which may be substituted by lower alkyl or lower alkanoyl; R<3> represents hydrogen or lower alkyl; A represents lower alkylene or carbonyl; and B and W are different from each other and each represents lower alkylene, carbonyl or a free bond. <CHEM>
Patent DE-69229677-D1 (DE)
Inventor: MACDONALD PETER
IPC: C07D241/08
Filed: 1992-10-22
Granted: 1999-09-02
Abstract: PCT No. PCT/GB92/01942 Sec. 371 Date Nov. 23, 1994 Sec. 102(e) Date Nov. 23, 1994 PCT Filed Oct. 22, 1992 PCT Pub. No. WO93/08172 PCT Pub. Date Apr. 29, 1993This invention provides a process for the preparing of (S) (+)-4,4'-(1-methyl-1,2-ethanediyl)-bis-(2,6-piperazinedione) (ICRF-187), by synthesizing a crude mixture comprising a 1,2-diaminopropane tetraacetic acid intermediate and byproducts; and then subjecting the tetraacetic acid intermediate, as part of the crude mixture, to ring formation in the presence of the byproducts, thereby producing ICRF-187 in commercially useful amounts.
Patent DE-69308851-D1 (DE)
Inventor: MASONI PIETRO
IPC: F16D41/10
Filed: 1993-07-02
Granted: 1997-04-17
Abstract: The invention relates to a speed variator in which the rotary motion of the drive shaft (1) is turned into oscillatory motion of variable amplitude via eccentric discs (2a, 2b) whose eccentricity can ce controlled by means of a control device (3) incorporated in the drive shaft (1) and the oscillatory motion is turned into rotary motion of the output shaft (9) via unidirectional drive systems (6) comprising a freewheel system. According to the invention , the speed variator is characterized in that the control device (3) for the eccentric discs (2a, 2b), incorporated in the drive shaft (1), is of hydraulic, pneumatic or electromechanical construction and in that the respective unidirectional drive systems (6a-6d) are reversible  in that they comprise a double acting freewheel system which is designed for driving the output shaft (9) in a first direction of drive and in a second, opposite direction of drive.
Patent DE-69316233-D1 (DE)
Inventor: SALVAGE RICHARD
IPC: H04R11/02
Filed: 1993-10-15
Granted: 1998-02-12
Abstract: This invention relates to electroacoustic transducers which incorporate a reed armature 17. Formations (25, 26, 27, 28 and 29) are provided for mounting the deflection of the reed 17. <IMAGE>
Patent DE-69326820-D1 (DE)
Inventor: GOLUNSKI STANISLAW EDMUND
IPC: C01B32/50
Filed: 1993-12-06
Granted: 1999-11-25
Abstract: A catalyst composed of metal oxide particles among which are uniformly incorporated, in order to reduce the operating temperature of the catalyst, palladium particles.
Patent DE-69327993-D1 (DE)
Inventor: COLLIN MARIANNE
IPC: C04B35/80
Filed: 1993-07-16
Granted: 2000-04-13
Abstract: According to the present invention there is now provided a method of manufacturing a whisker reinforced ceramic body comprising 2-50 % by volume whiskers and/or fibers and/or platelets and/or submicron particles in a ceramic matrix by powder metallurgical methods, i.e., dispersion in a suitable liquid, granulation, compaction and sintering. If the granulation is performed by freeze granulation a ceramic body with homogeneous structure with essentially no granule borders is obtained.
Patent DE-69332839-D1 (DE)
Inventor: HOHLA KRISTIAN
IPC: A61F9/01
Filed: 1993-09-30
Granted: 2003-05-08
Abstract: A apparatus and method for controlling an apparatus for removing tissue from the eye performs various types of corrections using a relatively large beam, but oscillating, or dithering, that being to prevent reinforcing ridges from being formed during the tissue removal process. Further, various types of correction, such as hyperopia and astigmatism correction, are performed using a large beam that is scanned over the area to be ablated using overlapping shots. Further, the epithelium in the area to be treated is removed using an infrared fluorescent dye to dye the epithelium, and then observing the fluorescent patterns from the epithelium area to be removed. Once a certain area is no longer fluorescent after laser shots, smaller shots are then applied, selectively removing the epithelium from the remaining regions. Again, the fluorescence patterns are observed, and the process is repeated until no epithelium remains. At this point, all of the epithelium is removed, and further a map is created of the initial epithelial thickness at each point in the area from which the epithelium was removed.
Patent DE-69401696-D1 (DE)
Inventor: RAMBAUD PASCAL
IPC: E01F9/627
Filed: 1994-11-09
Granted: 1997-03-20
Abstract: The support post (1) for a barrier for protecting against falling rocks includes a shaft (10) bearing on the ground (2) at its foot, and a base (11) on which the shaft (10) is fixed rigidly by means of gussets (15). An attachment rod (5) is driven substantially perpendicularly into the ground as far as an anchor (4) (cement block), according to the so-called exploded pile technique, and passes through a central region (11b) of the base. A coil spring (13) is threaded onto the rod and is held in compression by a nut (14). The base thus bears on the ground (2) by means of prestressing of the spring (13). The lateral forces on the post (1), resulting from the impact of rocks on the barrier, are compensated for by tilting of the base (11) about a tangent to its periphery (11a), against the compression of the spring (13). The stresses on the post are therefore damped, and positioning of the post requires only a single anchoring point. <IMAGE>
Patent DE-69431430-D1 (DE)
Inventor: KATO NAOKO
IPC: A61K38/00
Filed: 1994-03-02
Granted: 2002-10-31
Abstract: A dermal preparation for treatment of skin wounds containing as an active ingredient human blood coagulation factor XIII. This preparation may further contain aprotinin. The dermal preparation, when applied to damaged skin, especially burnt or scalded skin, can exert a superior delivery of the active ingredient, human blood coagulation factor XIII, to affected tissue, as compared with the case of intravenous administration, and can be administered without assistance of a physician.
Patent DE-69504465-D1 (DE)
Inventor: GALLUZZI CARLO
IPC: F42B7/04
Filed: 1995-12-15
Granted: 1998-10-08
Abstract: Shotgun pellets consist of virtually spherical bodies exhibiting a knurled surface made up of a plurality of protuberances (13) and depressions (14). The tips (15) of the protuberances constitute virtually deformable external surfaces of the pellets. The protuberances (13) may cover the entire surface of the pellet and have a virtually pyramidal shape, the height of these protruberances (13) with respect to the bottom of the depressions (14) being virtually between 0.15% and 20% of the pellet diameter, preferably around 5% and in any case greater than 15 mu m (micrometer). The pellet may be made from soft iron with Vickers hardness between 80 and 120 HV, preferably between 90 and 100 HV. <IMAGE>
Patent DE-69510243-D1 (DE)
Inventor: BOTTORFF KYLE J
IPC: D21H17/14
Filed: 1995-02-03
Granted: 1999-07-22
Abstract: A process of using paper in high speed converting or reprographic operations, the paper made under alkaline conditions and sized with a 2-oxetanone sizing agent that is not solid at 35 DEG C. Fine paper that is sized with a 2-oxetanone alkaline sizing agent and that does not encounter machine feed problems in high speed converting or reprographic machines, including continuous forms bond paper and adding machine paper, envelope paper, continuous forms bond paper and adding machine paper, and paper products of the processes, as well as certain novel sizing agents.
Patent DE-69512817-D1 (DE)
Inventor: REETZ MANFRED T
IPC: C11C1/04
Filed: 1995-03-04
Granted: 1999-11-25
Abstract: A process for the preparation of immobilized lipases through reaction on a silica matrix containing non-hydrolyzable organic substituents attached through Si-C bonds.
Patent DE-69515474-D1 (DE)
Inventor: HEED BJOERN
IPC: B21D13/04
Filed: 1995-05-02
Granted: 2000-04-13
Abstract: The invention regards a recuperative heat exchanger for the exchange of heat between two media across a heat transferring wall. According to the invention the heat transferring wall is made from a shaped patterned sheet which is folded repeatedly to form a multi-layered package (12) which is enclosed in a casing (15, 21), so that the sheet, owing to its configuration, after folding forms a package of alternating flow channels with connecting ports (22-25) for the two media at two opposite sides of the sheet package, said sheet being sealed against the casing at the bottom and the top of the package and at the two ends of the package so that leakage between the two media is prevented. The invention also relates to a method of producing such a heat exchanger.
Patent DE-69518240-D1 (DE)
Inventor: LAVON DEAN
IPC: A61F13/49
Filed: 1995-05-03
Granted: 2000-09-07
Abstract: An absorbent article having an expandable component. The expandable component comprises a compressed, resilient element disposed within an air impermeable envelope. The compressed element provides the absorbent article with a thin, low bulk profile prior to use of the disposable absorbent article, thereby reducing shipping and storage space. At the point of use of the absorbent article, the air impervious envelope is opened, thereby permitting entry of air into the envelope and expansion of the compressed element. In one embodiment the expandable component is a spacer for maintaining fecal void space in a disposable diaper. Alternatively, the expandable component can provide displacement of the topsheet relative to the backsheet along the longitudinal centerline of a sanitary napkin.
Patent DE-69519720-D1 (DE)
Inventor: BERGERUS CHRISTER
IPC: G01B21/08
Filed: 1995-09-08
Granted: 2001-02-01
Abstract: PCT No. PCT/SE95/01010 Sec. 371 Date May 8, 1996 Sec. 102(e) Date May 8, 1996 PCT Filed Sep. 8, 1995 PCT Pub. No. WO96/07871 PCT Pub. Date Mar. 14, 1996A measuring device is provided for measuring one or more properties, such as thickness and tension profiles of a thin object, especially a fabric. The measuring device includes an upper mobile member adapted to be placed on the top side of the thin object, a lower mobile member adapted to be placed on the bottom side of the thin object, directly below the upper mobile means, magnets for holding together the upper and the lower mobile members with the thin object in between without damaging the thin object, and a measuring device provided on at least one of the mobile members for measuring the properties of the thin object. The mobile members are moveable together or separately across the surface of the thin object.
Patent DE-69522342-D1 (DE)
Inventor: ASHWORTH ANTHONY
IPC: A61P35/00
Filed: 1995-12-22
Granted: 2001-09-27
Abstract: PCT No. PCT/GB95/03029 Sec. 371 Date Aug. 29, 1997 Sec. 102(e) Date Aug. 29, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/20180 PCT Pub. Date Jul. 4, 1996A piperazinedione of general formula (I): wherein R1 is selected from hydrogen; a group of formula -(NH)t-COR3 wherein t is 0 or 1 and R3 is an organic substituent as defined herein; a group of formula (D):  and a group of formula (E): and the pharmaceutically acceptable salts thereof are useful as modulators of multi-drug resistance.
Patent DE-69528605-D1 (DE)
Inventor: LARSEN PETER H
IPC: A23C3/00
Filed: 1995-07-17
Granted: 2002-11-21
Abstract: PCT No. PCT/SE95/00864 Sec. 371 Date Jan. 16, 1998 Sec. 102(e) Date Jan. 16, 1998 PCT Filed Jul. 17, 1995 PCT Pub. No. WO96/36238 PCT Pub. Date Nov. 21, 1996A method for continuous production of consumer milk with a variable fat content including microfiltration of a flow of skim milk. From the microfilter there is obtained a retentate flow and a permeate flow. The permeate flow of skim milk is subjected to a heat treatment and is then mixed with a partial flow of high temperature treated cream product in a desired amount. From this, there is obtained consumer milk with a good keeping quality.
Patent DE-69530855-D1 (DE)
Inventor: DUBROW S
IPC: G01N15/14
Filed: 1995-09-22
Granted: 2003-06-26
Abstract: An assay and sample mixture for the enumeration of fluorescently stained target components of a whole blood sample by an imaging instrument. The sample preparation method ensures that the amount of target components per unit of volume of the whole blood sample is preserved by elimination of certain non-quantitative preparation steps while producing an even hematocrit layer within a scan capillary. Typical target components include white blood cells that express certain surface antigens, such as CD-4 and CD-8 proteins. To inhibit aggregation of the red blood cells, a reagent is added to an aliquot of whole blood sample. The aliquot of whole blood is mixed and with a preselected amount of a fluorescent dye and ligand complex which tags the target components. The sample and fluorescent complex are allowed to incubate a sufficient amount of time to bind enough of the fluorescent complex to the target components to provide a fluorescent signal from the target components which will be distinguishable from the fluorescent signal from the unbound fluorescent complex in the sample. The resulting mixture allows the imaging instrument to detect peak intensities of fluorescence from the target components, thereby allowing the target components to be volumetrically enumerated with an improved level of accuracy and efficiency.