baber/WOPTO huggingface dataset:
Patent AU-2021202257-A1 (AU)
Title: Methods for treating brain metastasis
Inventor: MASSAGUE JOAN
IPC: A61K31/337
Filed: 2021-04-14
Abstract: METHODS FOR TREATING BRAIN METASTASIS 
Abstract 
The present invention relates to methods for treating brain metastasis by inhibiting gap 
junction functionality. It is based, at least in part, on the discovery that cancer cells expressing 
Protocadherin 7 and Connexin 43 form gap junctions with astrocytes that promote the growth of 
brain metastases, and that inhibition of Protocadherin 7 and/or Connexin 43 expression in cancer 
cells reduce progression of brain metastases. It is further based on the discovery that treatment 
with gap junction inhibitors tonabersat and meclofenamate inhibited progression of brain 
metastatic lesions and enhanced the anti-cancer activity of the conventional chemotherapeutic 
agent, carboplatin.
Patent AU-2021203692-A1 (AU)
Title: Systems, articles and methods related to providing customized cooking instruction
Inventor: YOUNG CHRISTOPHER CHARLES
IPC: G06Q50/12
Filed: 2021-06-04
Abstract: SYSTEMS, ARTICLES AND METHODS RELATED TO 
PROVIDING CUSTOMIZED COOKING INSTRUCTION 
ABSTRACT 
A method and of operation in a processor-based food preparation guidance system and 
cooking device, the method comprising: receiving, via a communications device, a 
request for preparation guidance for a food product; in response to the received request, 
causing an image or video in a first series of images or videos to be displayed by the 
communications device, wherein each image or video in the first series of images or 
videos depicts the food product after cooking the food product, wherein each image or 
video of the first series of images or videos depicts a different gradation of at least one 
first characteristic of the food product; receiving, via the communications device, a 
selection of one of the gradations of the at least one first characteristic of the food 
product; in response to receiving the selection of one of the gradations of the at least 
one first characteristic of the food product, causing an image or video of a subset of a 
second series of images or videos to be displayed by the communications device, 
wherein the subset of the second series of images or videos is determined from the 
second series of images or videos using the selection of one of the gradations of the at 
least one first characteristic of the food product such that the subset shows images or 
videos where an outcome of cooking the food product is possible or desirable with the 
first characteristic of the food product, wherein the subset includes a plurality of images 
or videos, wherein each image or video in the second series of images or videos depicts 
a different gradation of at least one second characteristic of the food product; receiving, 
via the communications device, a selection of one of the gradations of the at least one 
second characteristic of the food product; determining at least one food preparation 
parameter for the food product based at least in part on the received selections of one of 
the gradations of the at least one first characteristic and one of the gradations of the at 
least one second characteristic of the food product; and sending the at least one food 
preparation parameter to a cooking device; wherein the cooking device is configured to 
automatically cook the food product based at least in part on the at least one food 
preparation parameter.
Patent AU-2021206270-A1 (AU)
Title: Compositions and methods for the targeting of PCSK9
Inventor: OAKES BENJAMIN
IPC: C12N15/113
Filed: 2021-01-08
Abstract: Provided herein are systems comprising Class2, Type V CRISPR polypeptides, guide nucleic acids (gNA), and optionally donor template nucleic acids useful in the modification of a PCSK9 gene. The systems are also useful for introduction into cells, for example eukaryotic cells having mutations in the PCSK9 gene. Also provided are methods of using such CasX:gNA systems to modify cells having such mutations.
Patent AU-2021211131-A1 (AU)
Title: Foldable structure for a sunshade, a shutter or a fence
Inventor: MARIN RODRIGUEZ FRANCISCO JAVIER
IPC: E06B7/092
Filed: 2021-01-21
Abstract: A foldable structure for a sunshade, a shutter or a fence, comprising at least one guiding member (10); a plurality of displaceable elements (20) slidably connected to said guiding member (10) forming a row (2), a stroke end (54), a first actuator (31) connected to fist displaceable element (20) of the row (2), foldable spacers (40) connecting each pair of successive displaceable elements (20), and a spacer guide (50) including successive first portion (51), second portion (52), third portion (53), wherein the second portion (52) urge the foldable spacers (40) from a first folding position to a second folding position; and wherein a second actuator (32) produces a relative movement between the second portion (52) of the spacer guide (50) and the stroke end (54) to adjust the longitude of the third portion (53), said second actuator (32) being in coordination with the first actuator (31).
Patent AU-2021218004-A1 (AU)
Title: Constructs having a SIRP-alpha domain or variant thereof
Inventor: PONS JAUME
IPC: A61K39/395
Filed: 2021-08-16
Abstract: The present disclosure features signal-regulatory protein a (SIRP-a) polypeptides and constructs that 
) are useful, e.g., to target a cell (e.g., a cancer cell or a cell of the immune system), to increase 
phagocytosis of the target cell, to eliminate immune cells such as regulatory T-cells, to kill cancer 
cells, to treat a disease (e.g., cancer) in a subject, or any combinations thereof. The SIRP-a constructs 
include a high affinity SIRP-a D1 domain or variant thereof that binds CD47 with higher affinity than 
a wild-type SIRP-a. The SIRP-a polypeptides or constructs include a SIRP-a D1 variant fused to an 
Fe domain monomer, a human serum albumin (HSA), an albumin-binding peptide, or a polyethylene 
glycol (PEG) polymer. Compositions provided herein include (i) a polypeptide including a signal
regulatory protein a (SIRP- a) D1 variant and (ii) an antibody.
Patent AU-2021221695-A1 (AU)
Title: Bispecific antibodies against CD3epsilon and BCMA for use in treatment of diseases
Inventor: VU MINH DIEM
IPC: A61P35/00
Filed: 2021-08-25
Abstract: BISPECIFIC ANTIBODIES AGAINST CD3EPSILON AND BCMA FOR 
USE IN TREATMENT OF DISEASES 
ABSTRACT 
The disclosure relates to bispecific antibodies against CD3c and BCMA for use in the treatment 
of diseases. The disclosure provides methods of determining the responsiveness of a patient to 
such treatment and relates to diagnostic assays.
Patent AU-2021221774-A1 (AU)
Title: Database management and graphical user interfaces for managing blood glucose levels
Inventor: MCRAITH KEVIN
IPC: G06F15/00
Filed: 2021-08-25
Abstract: Methods and devices include database management and graphical user 
interfaces for measurements collected by analyzing blood.
Patent AU-2021243856-A1 (AU)
Title: Position correction using towed sensor
Inventor: SONNIER CARL JAMES
IPC: G01S7/539
Filed: 2021-03-25
Abstract: Aspects of the subject technology relate to a method of correcting sensor position. The method comprises transmitting one or more first pulses of a first frequency range towards a first portion of a seabed and one or more second pulses of a second frequency range towards a second portion of the seabed, and receiving a first set and second set of backscattered data. The method further includes processing the first and second set of backscattered data to form a first and second set of image data and comparing the first set and second set of image data. The method further includes creating one or more error vectors between the first set and second set of image data, and updating the first set of backscattered data based on the one or more error vectors to produce an updated set of image data.
Patent AU-2021245263-A1 (AU)
Title: Aziridine spinosyn derivatives and methods of making
Inventor: CALABRESE ANDREW
IPC: C07D491/04
Filed: 2021-10-11
Abstract: Compositions including derivatives of spinosyns of the following formulae and methods for 
the production of derivatives of spinosyns are provided. The spinosyn derivatives described 
herein include those functionalized on the C-5,6 double bond to provide an aziridine ring 
system. The method produces spinosyn derivatives that exhibit activity towards insects, 
arachnids, and nematodes and are useful in the agricultural and animal health markets.  
NH 
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Patent AU-2021250838-A1 (AU)
Title: Window antennas
Inventor: SHRIVASTAVA DHAIRYA
IPC: H01Q1/22
Filed: 2021-10-11
Abstract: WINDOW ANTENNAS 
ABSTRACT OF THE DISCLOSURE 
In one aspect, an apparatus is described that includes a transparent pane having a first surface 
and a second surface. An electrochromic device is arranged over the second surface that 
includes a first conductive layer adjacent the second surface, a second conductive layer, and an 
electrochromic layer between the first and the second conductive layers. The apparatus further 
includes at least one conductive antenna structure arranged over the second surface.
Patent AU-2021256776-A1 (AU)
Title: Method for obtaining a botanical extract
Inventor: ROIG ALMIRALL FRANCISCO JAVIER
IPC: A61K36/44
Filed: 2021-04-14
Abstract: The present invention discloses a method for preparing a botanical extract, characterised in that it comprises the steps of: (a) extracting plant matter with ultrapure water, and separating the solid plant matter from the liquid fraction; (b) concentrating the liquid fraction; (c) purifying the liquid fraction obtained in step (b) by tangential flow filtration.
Patent AU-2021260960-A1 (AU)
Title: Formulation, dosage regimen, and manufacturing process for heterodimeric Fc-fused proteins
Inventor: BIGELOW MITCHELL
IPC: A61K9/00
Filed: 2021-04-22
Abstract: The present invention relates to pharmaceutical formulations for heterodimeric Fc-fused proteins which are advantageous for achieving higher titers of the proteins during production, higher stability during storage, and improved efficacy when used as a therapeutic. Also provided are dosage regimens for such heterodimeric Fc-fused proteins and pharmaceutical formulations for use in treating cancer, such as locally advanced or metastatic solid tumor.
Patent AU-2021267945-A1 (AU)
Title: Modular systems configurable to enable multiple methods for producing edible extractions
Inventor: ALMAGOR OMRI
IPC: A47J31/46
Filed: 2021-07-05
Abstract: Disclosed herein is a system that includes several components that may be coupled in different configurations to form a modular, compact system that may produce a solution from a solute material via the application of a solvent for an individual's consumption. Each resultant modular system may be sized to be placed over a container to both receive the solution and enable an individual to drink the solution such as a beverage cup or mug in an embodiment. Several components of many of a system may be coupled to enable an individual or user to employ different method(s) to produce a desired solution.
Patent AU-2021273576-A1 (AU)
Title: Model integration tool
Inventor: INDURTHIVENKATA RAJESH
IPC: G06F9/44
Filed: 2021-11-24
Abstract: Certain aspects involve building and debugging models for generating source code 
executed on data-processing platforms. One example involves receiving an electronic data
processing model, which generates an analytical output from input attributes weighted with 
respective modeling coefficients. A target data-processing platform is identified that requires 
bin ranges for the modeling coefficients and reason codes for the input attributes. Each bin 
range identifies a valid range of input attribute values for a modeling coefficient. The reason 
codes indicate impacts of different input attributes on the analytical output. A user interface 
is provided for specifying bin ranges and reason codes. Bin ranges and reason codes are 
identified from input received via the interface. Modeling code is generated that implements 
the electronic data-processing model with the bin ranges and the reason codes. The processor 
outputs source code, which is generated from the modeling code, in a programming language 
used by the target data-processing platform.
Patent AU-2021276154-A1 (AU)
Title: System and method of in vivo testing for recently viable dental cellular debris
Inventor: CROSS RANDOLPH
IPC: A61B5/00
Filed: 2021-03-30
Abstract: A system and method of in vivo testing for recently viable dental cellular debris is disclosed herein. The present invention discloses a method and apparatus for detecting for the presence of cellular debris from an endodontic cavity and other areas of a tooth by testing for the presence of cellular debris such as Adenosine Triphosphate (ATP). The sample is collected from a tooth or endodontic cavity and combined with a chemical indicator which causes a detectable change in the indicator that is sensed by a luminescence reader. The level of ATP in a sample corresponds to the level of contamination still present in the tooth or endodontic cavity and can be used to determine what additional steps, if any, are necessary in order to clean and disinfect the tooth. This method of sampling the tooth or endodontic cavity allows for a rapid, chair-side, affordable, and easy to use method to determine the level of cellular contamination.
Patent AU-2021302483-A1 (AU)
Title: Attic vent fire protection system
Inventor: SHADE AMANDA E
IPC: E04D13/152
Filed: 2021-06-28
Abstract: A system that deploys attic vent covers when there is the immediate threat of fire, as well as methods and device relating thereto, is disclosed. This system includes varied cover types and deployment methods to utilize with a range of attic vents found suitable for use in residential and commercial construction.
Patent AU-2021304486-A1 (AU)
Title: Highly porous spider silk fibers
Inventor: GILAD HAIM MEIR
IPC: D01D5/38
Filed: 2021-07-05
Abstract: Compositions comprising a porous major ampullate spidroin protein (MaSp)-based fiber, wherein the fiber is characterized by a BET surface area of at least 100 m2/g are disclosed. Further, articles comprising the compositions and methods for producing same are disclosed.
Patent AU-2021386415-A1 (AU)
Title: Vial adapter
Inventor: HAMMERSHØJ PETER LUND
IPC: A61J1/20
Filed: 2021-11-29
Abstract: The invention regards a vial adapter, comprising two chamber parts in axial extension of each other, wherein the first chamber part is configured for slidably receiving at least a part of the vial crown, and the second chamber part is configured for slidably receiving at least a part of the vial body, wherein the first chamber part and/or the second chamber part comprises one or more ribs extending radially inwardly of the chamber wall.
Patent AU-2021391581-A1 (AU)
Title: Deuterated or partially deuterated n,n-dimethyltryptamine compounds
Inventor: RANDS PETER
IPC: C07D209/16
Filed: 2021-11-18
Abstract: The present invention relates to compounds of formula (I) as defined herein, which comprise a greater proportion of deuterium to protium than naturally found in hydrogen; and compositions, including pharmaceutical compositions, comprising these compounds and optionally analogous compounds of formula (I), which are not deuterium-enriched. These compounds and compositions are of use in therapy, in particular in the treatment of psychiatric or neurological disorders. Varying the amounts of the different compounds within the compositions of the invention allows tailoring of the compositions' therapeutic effects. A particularly efficient synthetic method which enables compounds of formula (I) and related compounds of formula (I') is also provided.
Patent AU-2021416090-A1 (AU)
Title: Crosslinked helix dimer mimics of sos and methods of using same
Inventor: ARORA PARAMJIT
IPC: A61K38/00
Filed: 2021-12-23
Abstract: This invention relates to macrostructures (and pharmaceutical formulations containing them) that include an antiparallel coiled-coil, wherein the antiparallel coiled-coil comprises a first coil of Formula I and a second coil of Formula II: T
Patent AU-2022200698-A1 (AU)
Title: A hinge and method of attachment
Inventor: MURAUER MICHAEL JOSEF
IPC: E05D11/10
Filed: 2022-02-03
Abstract: A hinge is described including: a leaf attachment assembly which includes a front leaf 
portion and a rear leaf portion, and an insert portion; the front leaf portion is coupled to 
the rear leaf portion by way of threaded fasteners; the leaf attachment assembly is 
arranged to fit about a region of a glass panel, and the insert portion is received in a cut
out section provided in the panel; the front and rear leaf portions include opposed 
substantially planar engagement surfaces to frictionally engage with opposite sides of 
the glass panel; the insert portion includes protruding lugs which are receivable in 
corresponding recesses provided in the cut-out portion; the threaded fasteners are 
operable to cause the leaf attachment assembly to adopt an installation configuration 
and an installed configuration; in the installation configuration, the front and rear leaf 
portions may be moved apart to such an extent that the clearance between the lugs and 
one of the engagement surfaces is greater than the width of the panel; and in the 
installed configuration the panel is clamped between the engagement surfaces of the 
front and rear leaf portions.
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Patent AU-2022202620-A1 (AU)
Title: Needle array for electroporation device
Inventor: CAMPILLO-AGUSTI ALEJANDRO
IPC: A61N1/04
Filed: 2022-04-20
Abstract: An electroporation device with a needle array removably attached thereto, the needle array 
having a body, a shroud movable with respect to the body between a rest position and one 
or more actuated positions, and an auto-lock assembly. Where the auto-lock assembly is 
adjustable between a locked configuration, where the shroud is not movable with respect 
to the body, and an unlocked configuration, where the shroud is movable with respect to 
the body, and where biasing the shroud from the rest position to the one or more actuated 
positions and back to the rest position adjusts the auto-lock from the unlocked 
configuration to the locked configuration.
Patent AU-2022204924-A1 (AU)
Title: Data collection cloud system for electronic gaming machines
Inventor: O’HARA JEREMIAH
IPC: A63F9/24
Filed: 2022-07-08
Abstract: An application program interface (API) provides functionality to store device data 
from multiple protocols. A collection server hosting the API is configured to receive a data 
structure from a first sending device comprising first sending device data, wherein the data 
structure comprises a static portion and a dynamic portion, wherein the static portion 
comprises identifying information for the sending device, and where in the dynamic portion 
comprises the device data; and store the device data in accordance with the data structure.  
18870410_1 (GHMatters) P119456.AU
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Patent AU-2022206792-A1 (AU)
Title: Treating refractory migraine
Inventor: BIGAL MARCELO
IPC: A61P25/06
Filed: 2022-07-21
Abstract: TREATING REFRACTORY MIGRAINE 
Abstract 
Disclosed herein are methods of treating or reducing incidence of migraine and/or at least one 
secondary symptom associated with refractory migraine in a subject having refractory migraine 
comprising administering to the subject a 5 monoclonal antibody that modulates the CGRP 
pathway. Compositions for use in the disclosed methods are also provided. Antagonist antibody 
G1 and antibodies derived from G1 directed to CGRP are also described.
Patent AU-2022237836-A1 (AU)
Title: Process for preparing risdiplam
Inventor: ADAM JEAN-MICHEL
IPC: C07D519/00
Filed: 2022-03-16
Abstract: The present invention relates to a process for the preparation of 7-(4,7- diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2- a]pyrimidin-4-one derivatives useful as pharmaceutically active compounds.
Patent AU-2022252098-A1 (AU)
Title: Recovery of metals from metallic or metal-bearing materials
Inventor: PRETORIUS GERARD
IPC: C22B1/00
Filed: 2022-03-31
Abstract: A method of treating a metallic or metal-bearing material includes, in an oxidative or reductive digestion step, contacting the metallic or metal-bearing material with a reagent selected from ferric chloride (FeCl
Patent AU-2022259667-A1 (AU)
Title: Efficient voxelization for deep learning
Inventor: HAMP TOBIAS
IPC: G16B15/00
Filed: 2022-04-14
Abstract: The technology disclosed relates to efficiently determining which atoms in a protein are nearest to voxels in a grid. The atoms have three-dimensional (3D) atom coordinates, and the voxels have 3D voxel coordinates. The technology disclosed generates an atom-to-voxels mapping that maps, to each of the atoms, a containing voxel selected based on matching 3D atom coordinates of a particular atom of the protein to the 3D voxel coordinates in the grid. The technology disclosed generates a voxel-to-atoms mapping that maps, to each of the voxels, a subset of the atoms. The subset of the atoms mapped to a particular voxel in the grid includes those atoms in the protein that are mapped to the particular voxel by the atom-to-voxels mapping. The technology disclosed includes using the voxel-to-atoms mapping to determine, for each of the voxels, a nearest atom in the protein.
Patent AU-2022270294-A1 (AU)
Title: Method for producing a cemented carbide material having a reinforced binder phase
Inventor: FRIEDERICHS HEIKO
IPC: B22F1/05
Filed: 2022-04-21
Abstract: The invention relates to a cemented carbide material, in particular a hard metal, comprising 70-95 wt.%, preferably 80-95 wt.%, tungsten carbide in dispersed form, and a binder phase, the binder phase comprising metallic binder material, the metallic binder material comprising Co, the binder phase comprising intermetallic phase material and/or the dissolved elements Ni and Al, said intermetallic phase material, if present, being formed according to the structural formula (M,Y)3 (Al,X), where M = Ni, Y = Co and/or another constituent, and X = tungsten and/or another constituent, said binder phase having the following chemical element composition: Ni > 25 wt.%, Al > 4 wt.%, and the remainder Co and dissolved binder constituents, for example W and/or C. Such a cemented carbide material is characterised by a high resistance to wear and at the same time a high breaking strength.
Patent AU-2023200060-A1 (AU)
Title: Dermal image capture
Inventor: CHIKKANARAVANGALA SHADAKSHARI D
IPC: G01N21/29
Filed: 2023-01-05
Abstract: A method of performing skin disease screening, the method comprising capturing an image 
of a skin surface with a pre-selected combination of light wavelength, lens magnification, and 
filtering, the skin surface including an area of interest; preprocessing the captured image of 
the skin surface; segmenting the preprocessed image by identifying boundaries between the 
area of interest and the skin surface, and partitioning the area of interest from the skin 
surface; extracting features from the segmented image; and providing a recommended skin 
disease diagnosis of the area of interest by performing one or more computer-aided 
algorithms that use the extracted features as inputs.  
Figure 17
17/26 
1700 
1702 
Preprocess Image 
Segment 1704 
Preprocessed Image 
1706 
Extract Features from 1 
Segmented Image 
1708 
Provide Recommended / 
Diagnosis to User 
1710 
Receive Diagnostic V 
Decision from User 
1712 
Send Image and V 
Diagnostic Decision 
FIG.17