baber/WOPTO huggingface dataset:
Patent CA-2577370-A1 (CA)
Inventor: GAO CHANGSHOU
IPC: C07K1/00
Filed: 2005-08-15
Abstract: The present invention relates to novel Fc variants of antibodies that immuno-specifically binds to Integrin .alpha.V.beta.3. The Fc variants comprise a variable region that immunospecifically binds to Integrin .alpha.V.beta.3 and a Fc region that further comprises at least one novel amino acid residue which may provide for enhanced effector function. More specifically, this invention provides Fc variants that have modified binding affinity to one or more Fc.gamma.R and/or C 1 q. Additionally, the Fc variants have altered antibody dependent cell-mediated cytotoxicity (ADCC) and/or complement dependent cytotoxicity (CDC) activity. The invention further provides methods and protocols for the application of said Fc variants of an antibody that immunospecifically binds to Integrin .alpha.V.beta.3, particularly for therapeutic purposes.
Patent CA-2578271-A1 (CA)
Inventor: FRITSCHI HUBERT
IPC: E04B1/76
Filed: 2007-02-12
Abstract: A construction element for heat insulation between a ceiling and a balcony is provided, which includes an insulating body and reinforcement elements crossing the insulating body that are connected to both construction parts. Here, horizontally adjacent to the insulating body, at least one additional insulating body is arranged, with an additional tensile reinforcement element being provided in a lower half thereof for earthquake stress, protruding in the horizontal direction in reference to the insulating body.
Patent CA-2578439-A1 (CA)
Title: A safety device for preventing overcharge of secondary batteries and secondary batteries therewith
Inventor: LEE JAE-HYUN
IPC: H01M10/50
Filed: 2005-07-21
Abstract: An object of the present invention is to provide the device for protecting a secondary battery safely from overvoltage and overheating caused by the overcharge by using simple safety device, which provides a contacted safety device which connects between a constant voltage element showing a discharge characteristic in the state of overvoltage and a MIT (metal insulator transition) element showing a discharge characteristic in the state of overheating. Each of the constant voltage element and the MIT element are connected in parallel between a cathode lead and an anode lead of the secondary battery. The contacted safety device has a characteristic combining a discharge/heat dissipation characteristic of the constant voltage element and a discharge characteristic of the MIT element which immediately responds to the heat dissipation of the constant voltage element, resulting in effect of preventing overcharge advantageously since the contacted safety device makes discharge in terms of 2 factors of voltage and temperature in case of overcharge.
Patent CA-2581355-A1 (CA)
Inventor: TARRES-CALL JORDI
IPC: A61K39/295
Filed: 2005-10-06
Abstract: A vaccine composition and method which is effective in preventing or ameliorating Avian Influenza Virus infection is set forth herein. The vaccine contains at least two inactivated strains of avian influenza virus, wherein the combined haemoagglutinin (HA) total is at least about 200 HA/dose of the vaccine composition, and wherein each of the strains presents at least about 128 HA/dose, and further wherein one of the strains has the same HA subtype as that of a challenge virus, and wherein at least one of the strains has a different NA subtype than the challenge virus.
Patent CA-2582303-A1 (CA)
Title: Instrumentality for sequestering liquids based on density: method and apparatus
Inventor: COELHO PHILIP H
IPC: A61M31/00
Filed: 2005-08-16
Abstract: An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into a device adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the device to control the operation of valves directing the collection of each component. The sensor may be reading one or more of the following characteristics: infrared, optics, density, weight, radioactive, fluorescense, color, magnetism, ultrasonic, capacitance wherein the characteristic is inherent in the blood and blood component or is an additive. Each component may then be separated into its own storage container. The preferred sensors include optics and weight. Besides blood density separation, the device may contain a solution including cells, proteins, subcellular particles or viruses which may be mixed with affinity media or antibodies prior to separation.
Patent CA-2588539-A1 (CA)
Title: Cold flow improvers for vegetable or animal fuel oils
Inventor: KUPETZ MARKUS
IPC: C10L1/19
Filed: 2007-05-15
Abstract: The present invention relates to a fuel oil additive comprising A) a copolymer of ethylene and from 13 to 17 mol% of at least one acrylic ester or vinyl ester having a C1-C18-alkyl radical and a melt viscosity V140 of not more than 80 mPas, and B) a comb polymer comprising structural units formed from B1) at least one olefin as monomer 1, which bears at least one C8-C18-alkyl radical on the olefinic double bond, and B2) at least one ethylenically unsaturated dicarboxylic acid as monomer 2, which bears at least one C8-C16-alkyl radical bonded via an amide and/or imide group, in which the parameter Q <IMG> in which w1 is the molar proportion of the individual chain lengths ni in the alkyl radicals of monomer 1, w2 is the molar proportion of the individual chain lengths n2 in the alkyl radicals of the amide and/or imide groups of monomer 2, n1 are the individual chain lengths in the alkyl radicals of monomer 1, n2 are the individual chain lengths in the alkyl radicals of the amide and/or imide groups of monomer 2, i is the serial variable for the chain lengths in the alkyl radicals of monomer 1, and j is the serial variable for the chain lengths in the alkyl radicals of the amide and/or imide groups of monomer 2 assumes values of from 23 to 27.
Patent CA-2589817-A1 (CA)
Title: Oral appliance with heat transfer mechanism
Inventor: ALTSHULER GREGORY B
IPC: A61N5/06
Filed: 2005-12-09
Abstract: Oral phototherapy applicators are disclosed that are sized and shaped so as to fit at least partially in a user~s mouth with a plurality of bristles of elongate shape coupled to an apparatus body. The applicators can be adapted to brush the user~s teeth and further include at least one radiation emitter coupled to the body to provide phototherapeutic radiation to a portion of the oral cavity other than tissue in contact with the bristles. In one embodiment, the applicator include a heat transfer element, such as, for example a fluid pump.
Patent CA-2594106-A1 (CA)
Title: Preparation of ketone amides
Inventor: KUO SHEN-CHUN
IPC: C07D401/06
Filed: 2006-01-05
Abstract: The present invention discloses a novel process to prepare ketone amides, which are useful intermediates for the preparation of antagonists of CCR5 receptor and therefore useful for the treatment of HIV virus infected mammals.  It specifically discloses a novel process to synthesize 1 -(2,4-dimethylpyrimidine-5-carbonyl)-4-piperidone, 1 -[(2,4-dimethyl-3-pyridinyl)carbonyl]-4-piperidone and related compounds. A salient feature of the invention is the use of a three-phase reaction medium with an organic phase and a buffer salt slurry. (formule I)
Patent CA-2595154-A1 (CA)
Title: Air inlet and method for a highspeed mobile platform
Inventor: WILLIE ROBERT H
IPC: B64D13/02
Filed: 2007-07-27
Abstract: An inlet apparatus and method for use with a cabin air compressor on a high speed, airborne mobile platform, such as a commercial or military aircraft. The apparatus includes a Pitot inlet of a desired shape that is supported outside an exterior surface of a fuselage of the aircraft by a diverter structure. The diverter structure diverts a low energy portion of a boundary layer so that the low energy portion does not enter the Pitot inlet. The Pitot inlet receives the higher energy portion of the boundary layer and channels a ram airflow to an inlet of a cabin air compressor. The apparatus provides a recovery factor (RF) of at least about 0.8 at a cabin air compressor (CAC) inlet face, which keeps the electric power required to drive the CAC within available power limits, while minimizing the drag of the inlet apparatus.
Patent CA-2598024-A1 (CA)
Inventor: THOMSEN LEON A
IPC: G01V3/38
Filed: 2006-02-21
Abstract: There is provided herein a system and method of acquiring, processing, and imaging transient Controlled Source ElectroMagnetic (t-CSEM) data in ways that are similar to those used for seismic data. In particular, the instant invention exploits the time- distance characteristics of t-CSEM data to permit the design and execution of t-CSEM surveys for optimal subsequent processing and imaging. The instant invention illustrates how to correct t-CSEM data traces for attenuation and dispersion, so that their characteristics are more like those of seismic data and can be processed using algorithms familiar to the seismic processor. The resulting t-CSEM images, particularly if combined with corresponding seismic images, may be used to infer the location of hydrocarbon reservoirs.
Patent CA-2598975-A1 (CA)
Inventor: DAHLHEIMER JOHN C
IPC: F16J15/34
Filed: 2007-08-27
Abstract: A mechanical face seal includes an elastomeric boot including a bellows portion extending radially from a tube portion. The tube portion includes a flanged end having a tapered surface on a leading end and a flat surface on a trailing end. A  spring is disposed around the tube portion and has a first end disposed against the boot. A seal washer is disposed around the tube portion and engages a second end of the spring. The seal washer includes a radially outwardly extending portion that engages the bellows portion. A seal seat is disposed around the tube portion and has a face surface that is engaged by the seal washer. The seal seat is supported by a grommet having a retention lip for engaging the tube portion.
Patent CA-2600292-A1 (CA)
Title: Water sanitization system having safety features and removable filter
Inventor: CALDWELL CHRISTOPHER B
IPC: C02F1/78
Filed: 2006-03-17
Abstract: A removable disposable air dryer cartridge is provided for a small enterprise water ozonation system. The cartridge includes an air inlet to receive atmospheric air, a desiccant material to remove moisture, and a dry air outlet for interfacing with the ozonation system to provide dry air to an ozone generator. This facilitates better ozonation of water in the system, since dry air reacts better in an ozone generator, achieving higher concentrations of ozone gas, thus resulting in a better "kill rate" when ozonated water is applied to bacteria. The air dryer can be provided as a chamber of a combined air dryer and water filter cartridge, the other chamber being a water filter chamber having a water filter for extracting large particles of material from the water stream in order to prevent damage to the system.
Patent CA-2600866-A1 (CA)
Title: System and method for controlling access to features of a medical instrument
Inventor: BATCH RICHARD M
IPC: G06F21/30
Filed: 2006-03-03
Abstract: An access key is required for operation of features of a medical instrument. A  control program is used to control access to the operating features of the medical instrument. All programs of the medical instrument are validated for operation of any and all of the features of the medical instrument either alone or in any combination. However access to use of those features or combinations of features of the medical instrument requires an access key that is recognized by the control program. The pump may be usable in a basic operational configuration without entry of any access key; however, more advanced features will be disabled unless the operator enters a correct access key to enable one or more of those features. Operator input for enabled features will be accepted by the instrument but operator input for disabled features will not be accepted. Disabled features are not displayed, nor is information about them displayed. By means of the invention, the medical instrument and all of its control programs are completely validated for all uses and modes of operation during manufacture; however, users are restricted from use of certain features by means of the requirement for an access key.
Patent CA-2600929-A1 (CA)
Title: Methods of humanizing immunoglobulin variable regions through rational modification of complementarity determining residues
Inventor: SIMON KENNETH
IPC: C07K16/00
Filed: 2006-03-06
Abstract: The present invention is based, at least in part, on the discovery that strategic modifications of non-human donor antibody CDR residue(s) can be used to humanize antibodies. Such modifications modulate the 3D structural fit between donor antibody CDRs and human acceptor antibody framework regions that comprise the variable domains of a CDR-grafted antibody. Whereas prior art methods of humanization have relied on making framework substitutions (in which selected human framework residues are backmutated to the corresponding amino acid residue present in the non-human donor antibody), the instant invention is based, at least in part, on a method of humanizing antibodies in which selected CDR residues, and optionally adjacent FR residues, are changed in order to accommodate differences in FR amino acid sequences between donor and acceptor antibodies.
Patent CA-2601132-A1 (CA)
Title: Use of n-methylglycine and pharmaceutical compositions comprising n-methylglycine for treating neuropsychiatric disorders
Inventor: COYLE JOSEPH
IPC: A61K45/06
Filed: 1999-04-14
Abstract: A pharmaceutical composition comprising (i) at least one agonist of the glycine site of an NMDA receptor and (ii) a second therapeutic agent which is a antipsychotic, antidepressant, psychostimulants or Alzheimer's disease therapeutic. The agonist is D-alanine, a salt of D-alanine, an ester of D-alanine, alkylated D-alanine, a precursor of D-alanine, D-serine, a salt of D-serine, an ester of D-serine, alkylated D-serine, a precursor of D-serine, D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, a precursor of D-cycloserine, or alkylated D-cycloserine. The pharmaceutical composition is substantially free of D-cycloserine when the agonist is D-alanine, a salt of D-alanine, an ester of D-alanine, an alkylated D-alanine, or a precursor of D-alanine. Where the agonist is D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, a precursor of D-cycloserine, or alkylated D-cycloserine, the pharmaceutical composition comprises an amount of the agonist equivalent to 105-500 mg of D-cycloserine.
Patent CA-2601768-A1 (CA)
Title: Search engine that applies feedback from users to improve search results
Inventor: RIOS GORDON P
IPC: G06F7/00
Filed: 2006-03-17
Abstract: The present invention is directed to methods of and systems for ranking results returned by a search engine. A method in accordance with the invention comprises determining a formula having variables and parameters, wherein the formula is for computing a relevance score for a document and a search query;  and ranking the document based on the relevance score. Preferably, determining the formula comprises tuning the parameters based on user input. Preferably, the parameters are determined using a machine learning technique, such as one that includes a form of statistical classification.
Patent CA-2609186-A1 (CA)
Title: Methods of synthesizing substituted 3-cyanoquinolines and intermediates thereof
Inventor: CHEAL GLORIA KAREN
IPC: A61P35/00
Filed: 2006-04-28
Abstract: The invention is directed to methods of making substituted 3- cyanoquinolines, including compounds according to the following formula: (IV) The methods are amenable to large scale manufacture, avoid the use of chromatographic separations, and provide stable, high purity product more efficiently than in the prior art.
Patent CA-2610089-A1 (CA)
Title: Process for the preparation of n,n´- disubstituted oxabispidines
Inventor: ENSOR GARETH
IPC: C07D498/08
Filed: 2006-06-12
Abstract: There is provided a process for the preparation of a sulfonic acid salt of formula I, or a solvate thereof, which process comprises hydrogenating a sulfonic acid salt of formula II,. or a solvate thereof; in the presence of a solvent system consisting essentially of water, a C3-5 secondary alkyl alcohol and no more than 15% v/v of another organic solvent, wherein the sulfonic acid salt of formula I is optionally, without isolation, converted to a compound of formula IX, or a pharmaceutically-acceptable derivative thereof, wherein R1, R2, R3, R6, R7, R8, A, B and D have meanings given in the description.
Patent CA-2612906-A1 (CA)
Inventor: VOON GERARD
IPC: G06N20/00
Filed: 2007-12-21
Abstract: Nano radio walkie talkies that 1) can be switched from walkie talkie connection to 2) cellular phone world wide network with a flip of a switch, and/or 3) VOIP - 4) intern et capability (possibly plug and play into a lap top or note book and/or back pack compute r) and/or 5) e--mail, and/or 6) television and/or 7) movies library, and/or 8) text messaging and/or 9) stock market e-device, and/or 10) book down load reader, and/or 11) music down loa d, and/or 12) satellite television, and/or 13) satellite radio, and/or 14) tech language translator, and/or 15) micro/macro pattern mining and ranking of importance schedule planner (alarm ), and/or 16) Artificial Intelligence, and/or 17) mobile office software and document work sharing. We could make the components optional - modular plug and play with either docking, wire/socket connection and/or router Wii.
Patent CA-2613615-A1 (CA)
Inventor: GILBOA GALIT
IPC: B62B7/06
Filed: 2006-06-26
Abstract: The present invention relates to a baby and toddler carrier and in particular to a novel and improved baby and toddler carrier to be used by a parent or other caretakers for carrying a baby in a secure and comfortable way, both for the adult and for the baby, in various carrying positions, the carrier includes an elastic back and neck support, harness straps, and buckles, all of which enable carrying the baby in at least five different carrying positions.
Patent CA-2622870-A1 (CA)
Inventor: GENTILE ALFONSO
IPC: A61P35/00
Filed: 2006-09-12
Abstract: This invention provides dosage forms of a compound of formula 1, 5-[(Z)-(5-fluoro-2-oxo-1,2- dihydro-3H-indol-3-ylidene) methyl]-N-[(2S)-2- hydroxy-3-morpholin -4- ylpropyl] -2,4- dimethyl-1H- pyrrole-3- carboxamide, or pharmaceutically acceptable salts or solvates thereof. The invention further provides methods of treating abnormal cell growth in a patient, such as cancers, by administering the dosage forms to the patient. The invention further provides methods of treating an angiogenesis- or VEGF- related ophthalmic disorder in a patient, by administering the dosage form to the patient.
Patent CA-2624388-A1 (CA)
Title: Anti-pop open macrofasteners
Inventor: RAYCHECK JEROMY THOMAS
IPC: A44B11/25
Filed: 2006-09-28
Abstract: A tab and slot closure system has a tab member, a slot member, and an anti-pop open device. The tab member has a tab element which has a first region and a second region. The first region includes a proximal edge, and the second region includes a distal edge. The tab element is attached to the substrate element along a line of attachment. The slot member has an inboard portion, an outboard portion, and a slot disposed between the inboard portion and the outboard portion. The anti-pop open device is disposed on either the tab member or the slot member and reduces the likelihood of the tab member unintentionally disengaging the slot member when the tab and slot closure system is fastened.
Patent CA-2624400-A1 (CA)
Inventor: MOIDU ABDUL JALEEL K
IPC: G02B26/02
Filed: 2008-03-06
Abstract: A vertical comb electro-static actuator for rotating a micro-electro-mechanical micro-mirror device about a tilt axis or rotation. The rotor comb fingers of the comb drive extend from a sub-frame of the micro-mirror, which includes a prestressed layer for bending the rotor comb fingers at an angle to the substrate and mirrored platform, enabling the platform, the hinges, the rotor comb fingers and the stator comb fingers to be formed in the same layer, i.e. the same etching step.
Patent CA-2624484-A1 (CA)
Inventor: VAN DE VEN HENRICUS JOANNES MA
IPC: C23C14/20
Filed: 2006-09-26
Abstract: Disclosed is a method for producing a reflective, waterproof, steam-permeable membrane. Said method encompasses the following steps: a waterproof, steam-permeable membrane is provided; a carrier foil is provided; the membrane is applied to the carrier foil; a metallic surface is attached to the free surface of the membrane via a vacuum-steam process; a waterproof, steam-permeable covering layer is applied; the carrier foil is removed. Also disclosed is a reflective, waterproof, steam-permeable membrane comprising a metal coating that is provided with a continuous covering layer. The inventive membrane is characterized that at least 80 percent of the surface of the active metal coating are preserved on the membrane after three washing processes according to DIN EN ISO 6330:2000.
Patent CA-2625151-A1 (CA)
Title: Microorganisms having bad smell removal activity of organic waste and use thereof
Inventor: PARK SE JOON
IPC: A01N63/32
Filed: 2006-10-19
Abstract: The present invention relates to novel microorganisms having the efficiency of removing an offensive odor from organic waste and the use thereof. More particularly, the novel microorganisms have the effects of preventing or removing the offensive odor from organic waste, killing insects and fungi, preventing decomposition, and promoting digestion and fermentation. The inventive microorganisms have the effects of preventing or removing the offensive odor from organic waste and killing noxious insects and plant pathogenic fungi, can be used as feed additives and antibiotic substitutes, and also are useful for the preparation of fermented healthy foods.
Patent CA-2627694-A1 (CA)
Inventor: BOCK THOMAS-MATHIAS
IPC: B64D11/00
Filed: 2006-10-24
Abstract: The invention relates to a luggage cabinet (2) which is intended, in particular, for an aircraft cabin. The invention comprises a cabinet having a lower face (8), an upper face (12), an open face for accessing the compartment in order to place luggage (22) in the compartment or remove luggage therefrom and a base (10) which is disposed opposite the open face of the compartment. The lower face (8) of the compartment is essentially flat on the side of the open face and is raised close to the base (10). In addition, a groove (28) is provided in the area in which the raised part (26) of the lower face is connected to the base (10), the concavity of said groove being oriented towards the upper face (12) of the compartment.
Patent CA-2630827-A1 (CA)
Inventor: SZYMONSKI KRZYSZTOF A
IPC: B65B25/14
Filed: 2006-06-22
Abstract: A dispenser, and associated method for producing such dispenser, for interfolded disposable sheets includes a dispensing container (10) defining an interior volume sufficient for receipt of a clip of interfolded disposable sheets, the container including a first wall (20) with a dispensing opening (42) defined by a removable panel (22). At least a portion of an adhesive material (50) is disposed at a location on the removable panel such that the adhesive is not exposed to the interior volume of the container in an adhesive state. A clip of interfolded disposable sheets (12) is inserted into the interior volume of the container. After insertion of the clip, the adhesive material is exposed in an adhesive state to the interior volume of the container and contact is made between the adhesive and the uppermost sheet of the clip of interfolded sheets such that the removable panel is attached to the uppermost sheet.