baber/WOPTO huggingface dataset:
Patent EP-1572211-B1 (EP)
Inventor: WANG SHUDONG
IPC: A61P9/00
Filed: 2003-12-18
Granted: 2008-02-20
Abstract: The present invention relates to the use of a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein (A) one of X and Y is S, and the other is N; or one of X and Y is NH or N-R<SUP>5</SUP>, and the other is C-R<SUP>6</SUP>; "a" is a single bond; "b", "c", "d", "e" and "f" are single or double bonds so as to form a heteroaryl ring; R<SUP>1 </SUP>is is R<SUP>7 </SUP>with the proviso that R<SUP>1 </SUP>is other than H or Me; or (B) one of X and Y is S, and the other is NH or N-R<SUP>5</SUP>; "a" and "d" are each double bonds; "b", "c", "e" and "f" are each single bonds; R<SUP>1 </SUP>is oxo; and R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, and R<SUP>6 </SUP>are each independently H or R<SUP>7</SUP>; R<SUP>7 </SUP>is a group (CH<SUB>2</SUB>)<SUB>n</SUB>-R<SUP>8</SUP>, wherein n is 0, 1, 2, 3 or 4 and wherein R<SUP>8 </SUP>is selected from alkyl, aryl, heteroaryl, heterocycloalkyl, F, Cl, Br, I, CF<SUB>3</SUB>, NO<SUB>2</SUB>, CN, OH, O-alkyl, O-aryl, O-heteroaryl, O-heterocycloalkyl, CO-alkyl, CO-aryl, CO-heteroaryl, CO-heterocycloalkyl, COO-alkyl, NH<SUB>2</SUB>, NH-alkyl, NH-aryl, N(alkyl)<SUB>2</SUB>, NH-heteroaryl, NH-heterocycloalkyl, COOH, CONH<SUB>2</SUB>, CONH-alkyl, CON(alkyl)<SUB>2</SUB>, CONH-aryl, CONH-heteroaryl, CONH-heterocycloalkyl, SO<SUB>3</SUB>H, SO<SUB>2</SUB>-alkyl, SO<SUB>2</SUB>-aryl, SO<SUB>2</SUB>-heteroaryl, SO<SUB>2</SUB>-heterocycloalkyl, SO<SUB>2</SUB>NH<SUB>2</SUB>, SO<SUB>2</SUB>NH-alkyl, SO<SUB>2</SUB>N(alkyl)<SUB>2</SUB>, SO<SUB>2</SUB>NH-aryl, SO<SUB>2</SUB>NH-heteroaryl, or SO<SUB>2</SUB>NH-heterocycloalkyl, wherein said alkyl, aryl, heteroaryl, and heterocycloalkyl groups are optionally substituted with one or more groups selected from halogeno, NO<SUB>2</SUB>, OH, O-methyl, NH<SUB>2</SUB>, COOH, CONH<SUB>2 </SUB>and CF<SUB>3</SUB>; in the preparation of a medicament for treating diabetes. The compounds of the invention also have applications in the treatment of CNS disorders, alopecia, cardiovascular disorders and stroke.
Patent EP-1565491-B1 (EP)
Inventor: BICKNELL ROY
IPC: C12N15/13
Filed: 2003-11-20
Granted: 2010-03-31
Abstract: A method of inhibiting angiogenesis in an individual in need thereof comprising administering an antibody that selectively binds to the extracellular region of human magic roundabout (MR) to the individual. An antibody that has the amino acid sequences i) to iii), the amino acid sequences iv) to vi), or the amino acid sequences i) to vi). i) S A S S S V S Y M Y ii) L T S N L A S iii) Q Q W S S N P L T iv) D Y N L N v) V I N P N Y G T T S Y N Q K F K G vi) G R D Y F G Y. A method of inhibiting angiogenesis in an individual in need thereof comprising administering the extracellular domain (residues 1-467) of MR, or a fragment thereof that inhibits angiogenesis, to the individual. A method of inhibiting endothelial cell migration and/or proliferation comprising administering the extracellular domain of MR, or a fragment thereof that inhibits endothelial cell migration and/or proliferation.
Patent EP-1544208-B1 (EP)
Inventor: TERANISHI HIROTAKA
IPC: A61P3/06
Filed: 2003-08-07
Granted: 2010-05-26
Abstract: The present invention provides pyrazole derivatives represented by the general formula: <CHEM> wherein R<1> represents H, an optionally substituted C1-6 alkyl group etc.; one of Q and T represents a group represented by the general formula: <CHEM> or a group represented by the general formula: <CHEM> while the other represents an optionally substituted C1-6 alkyl group etc.; R<2> represents H, a halogen atom, OH, an optionally substituted C1-6 alkyl group etc.; X represents a single bond, O or S; Y represents a single bond, a C1-6 alkylene group etc. ; Z represents CO or SO2; R<4> and R<5> represent H, an optionally substituted C1-6 alkyl group etc.; and R<3>, R<6> and R<7> represent H, a halogen atom etc., pharmaceutically acceptable salts thereof or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT1 and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications or obesity, and pharmaceutical compositions comprising the same, pharmaceutical uses thereof, and intermediates for production thereof.
Patent EP-1572602-B1 (EP)
Inventor: BRADY FRANK
IPC: C07B59/00
Filed: 2003-12-19
Granted: 2007-05-09
Abstract: The invention relates to a process for the production of an [18F]fluorohaloalkane which comprises treatment of a solid support-bound precursor of formula (I): SOLID SUPPORT-LINKER-SO2—O—(CH2)nX  (I) wherein n is an integer of from 1 to 7 and X is chloro, bromo or iodo; with 18F− to produce the [18F]fluorohaloalkane of formula (II) 18F—(CH2)n—X  (II) wherein n and X are as defined for the compound of formula (I), optionally followed by (i) removal of excess 18F−, for example by ion-exchange chromatography; and/or (ii) removal of organic solvent.
Patent EP-1537704-B1 (EP)
Inventor: SCHULZ EGON
IPC: H04L45/42
Filed: 2003-08-06
Granted: 2008-01-09
Abstract: Disclosed is a method in which a connection (V) is routed from a first mobile station (MS1) to a second mobile station (MS2) via at least one additional mobile station (MS3), pieces of positional information (PI1..3) being detected via said mobile stations (MS1, MS2, MS3). A central routing device (R) determines a route for the connection (V) based on the pieces of positional information (PI1..3). The routing device (R) generates routing information (RI) corresponding to the determined route and transmits said routing information to the mobile stations (MS1, MS2, MS3).
Patent EP-1567460-B1 (EP)
Inventor: LIGI SYLVAIN
IPC: C03C17/00
Filed: 2003-10-17
Granted: 2012-01-18
Abstract: La présente invention concerne un procédé de décoration d'un objet en verre, du type récipient ou bouteille, consistant à : (a) projeter sur l'objet en verre un produit à base d'émail, (b) disposer l'objet traité dans un four à des fins de cuisson, à une température comprise entre 600 et 650°C pendant 10 à 25 minutes, (c) refroidir l'objet en verre émaillé ainsi obtenu, (d) et réaliser une fenêtre transparente sur l'objet en verre, caractérisé en ce qu'il consiste : (e) à déposer sur l'objet en verre une préparation d'émail réfractaire présentant une température de fusion supérieure à 700°C, de sorte que le dépôt recouvre une zone correspondant à la fenêtre transparente à réaliser, ce dépôt étant effectué avant l'étape (a), et à (f) mettre en oeuvre l'étape (d) grâce à un retrait du dépôt de la préparation d'émail réfractaire par voie mécanique, à l'issue de l'étape (c).
Patent EP-1566382-B1 (EP)
IPC: C07D251/62
Filed: 2004-01-17
Granted: 2007-05-23
Abstract: Process to increase melamine yield and to improve dust separation in the melamine production from urea in fluidized-bed catalytic processes. Process to increase melamine yield and to improve dust separation in the melamine production from urea in fluidized-bed catalytic processes comprises: transferring the process gas (containing melamine, non-converted isocyanic acid, melam, melem and other higher molecular nitrogen compounds) of the fluid-bed reactor into a filter-reactor (consisting of one or more ring-reactors filled with catalysts) to convert isocyanic acid to melamine; and reconverting higher molecular nitrogen compounds (especially melam and melem) to melamine by reaction with ammonia in the process gas (where the catalyst fines present in the process gas are removed).
Patent EP-1568961-B1 (EP)
Inventor: HOTZ RENE
IPC: F24H9/12
Filed: 2004-02-18
Granted: 2009-07-01
Abstract: The radiator has distribution ducts in which an internal pipe (7) is provided. The internal pipe is arranged so that the heating medium flows through its front flow opening facing the inlet/outlet. The internal pipe has a projection (16), or disc-like member which occludes the cross-section between the internal pipe and the distribution ducts.
Patent EP-1462815-B1 (EP)
Inventor: CHABOT PETRAULT CHRISTINE
IPC: G01R31/36
Filed: 2004-03-01
Granted: 2008-05-14
Abstract: The system has a temperature calculation unit for determining temperature of a battery. An initialization calculation unit receives information related to a voltage measured at the boundaries of the battery. A calculation unit (30) of a Kalman filter receives the voltage measured at the boundaries and the temperature of the battery to determine a state of load of the initialized battery. Independent claims are also included for the following: (a) a process for determining a state of a load of a battery; and (b) an application of a process of determination of a state of a load of a battery.
Patent EP-1493368-B1 (EP)
Inventor: TURI MARIANO
IPC: B02C7/16
Filed: 2004-06-02
Granted: 2005-10-26
Abstract: Each grinding disc (5, 7) has dogs (10, 11) locking it against relative rotation. These are each gripped in the respective holder (4, 8). The design is such that the torque exerted upon them, tends to load the disc towards the locked position, during grinding. This fixes them in their holders.
Patent EP-1720443-B1 (EP)
Inventor: PECHERER EUGENY
IPC: A61B1/267
Filed: 2004-02-29
Granted: 2009-04-29
Abstract: A metal laryngoscope blade with a resiliently elastically deformable metal blade hook-on fitting for removable double snap engagement into an operative intubation position on a laryngoscope handle with a correspondingly sized handle hook-on fitting.
Patent EP-1615838-B1 (EP)
Inventor: ASSARSSON INGE
IPC: B65D63/10
Filed: 2004-03-25
Granted: 2006-08-02
Abstract: A device in a cable tie is disclosed. The device includes an elongate band part of a certain width and thickness, which at one end has an elongate insertion narrower than the band part and terminates in a grip tab, and at its other end has a locking head. The locking head has, on the one hand, a through-opening which is intended for the band part and has substantially the same width as the band part but a height greater than the thickness of the band part and, on the other hand, a slot-shaped recess in one transverse wall of the opening, the width of which recess is such that it will allow the insertion part to be inserted into the opening via the recess, forming a band loop. On the band part there is toothing and in the locking head a locking tongue provided with toothing, which are designed, by way of a positive interlock, to lock the band part in relation to the locking head. In the area around the connection of the insertion part to the grip tab, there are wing-like projections extending transversely and out from the insertion part, which are thinner than the grip tab and which towards the latter terminate in a ridge. In forming the band loop, the ridge is designed, with the projections inserted into the through-opening of the locking head and engaging with the opposing walls of the opening, to abut the locking head. The fact that the projections are of thinner than the grip tab creates a clearance interval between the insertion part and the locking tongue.
Patent EP-1617996-B1 (EP)
Inventor: LIGTENBERG HARALD
IPC: F16L59/14
Filed: 2004-04-14
Granted: 2007-06-13
Abstract: The invention relates to a process for producing pipe sleeves made of mineral wool for insulating pipelines or for reducing the sound level in pipeline systems, comprising the following steps: providing a nonwoven web (11) made of mineral wool which is provided with an uncured binder, winding up the nonwoven web (11) on a winding mandrel (2) of a winder, curing the binder. Here, at least one reinforcing layer (12, 13) is provided before the nonwoven web (11) runs into the winder, in such a way that during the winding the said reinforcing layer becomes a constituent part of the pipe sleeve produced as a result.
Patent EP-1636078-B1 (EP)
Inventor: CURRY CHARLES EDWARD
IPC: B60T8/26
Filed: 2004-06-09
Granted: 2006-12-27
Abstract: A tool is connected to each of the front and rear braking circuits of a vehicle and is used to detect the functioning of a valve in the rear braking circuit. Each tool (10) comprises clamping means (11) for clamping around the hose of the circuits and one or more strain gauges (19) for measuring strain of the clamping means (11) as a result of pressure changes within the hose. The strain gauges (19) are operable to produce a signal indicative of the pressure within the hose and any pressure difference between the hoses is noted.
Patent EP-1651522-B1 (EP)
Inventor: OLEANDRI MAURIZIO
IPC: B65B61/24
Filed: 2004-08-05
Granted: 2006-11-08
Abstract: Products ( 2 ) presenting bevelled or rounded corner edges ( 35 ) are advanced singly and in succession along a predetermined path (P), each enveloped in a wrapper ( 11 ) of parallelepiped box-like shape, and directed ultimately into a station ( 15 ) where each product ( 2 ) is subjected to a finishing step that consists in deforming at least one part of the wrapper ( 11 ) and causing it thus to adhere to the surface of the relative product ( 2 ), in particular at the bevelled or rounded corner edges ( 35 ); thereafter, the finished products ( 2 ) are stacked and wrapped in respective stick packs ( 36 ) of which the longitudinal corner edges ( 38 ) will hug the corner edges ( 35 ) of the stacked products ( 2 ), adapting to the contours of the bevelled or rounded profile.
Patent EP-1779695-B1 (EP)
Inventor: EKLUND CARL
IPC: H04L29/06
Filed: 2004-08-17
Granted: 2008-12-31
Abstract: The invention relates to a method for supporting a handover of a mobile station 1 from a first radio access unit 3, 8 of a wireless communication network 2 to a second radio access unit 4, 9 of a wireless communication network 2. In order to improve a context transfer in the case of a handover of the mobile station 1, the mobile station 1 transmits information about its activity state to the second radio access unit 4, 9 when it is to be handed over to the second radio access unit 4, 9. The invention relates equally to such a mobile station, to such a second radio access unit, to a wireless communication system comprising such a mobile station and such a second radio access unit, and to a software code causing the transfer of information at the mobile station.
Patent EP-1610727-B1 (EP)
Inventor: SHU MARK C S
IPC: A61F2/24
Filed: 2004-03-31
Granted: 2009-04-29
Abstract: A heart valve prosthesis has a frame that includes at least one outwardly extending annular flange adjacent to a suturing ring and a band comprising an inwardly extending annular flange that is capable of engagement with the annular flange of the frame. A tortuous path is formed between the annular flange of the frame and the annular flange of the band that can engage and restrain a suture placed between them. One or more split portions or tab portions on the band are adapted to lock the band in engagement with the flange of the frame. Such a device can be used to more easily replace a heart valve by advancing a sutures through a suturing ring on the valve and the valvular rim such that they are brought outward of the flange extending from the frame and then advancing the band over the valve and over the sutures at a proximal, outflow end of the valve until the band engages the flange and captures the sutures between the band and the flange.
Patent EP-1675699-B1 (EP)
Inventor: HAVRDA FRANZ
IPC: B23B27/04
Filed: 2004-09-22
Granted: 2007-05-09
Abstract: Cutting tool, such as for end-cut and longitudinal turning, and for cutting grooves in a workpiece, which has an end or major cutting edge and two side or minor cutting edges, each of which are connected to the end or major cutting edge by two outer corners. Additional corner chip-breakers are formed between each of the outer corners and the ends of a chip-guiding rib.
Patent EP-1644909-B1 (EP)
Inventor: MULLERIS JEAN-JACQUES
IPC: G09F27/00
Filed: 2004-07-09
Granted: 2011-04-13
Abstract: The system has a menu board (1) with a front opening (10) having a housing (100). The opening receives a removable digital control display device (2) that includes a front part formed by a flat display screen (200). The device (2) has a mechanical and electrical interface to establish a connection with a power supply source and to maintain the device (2) in the housing in a detachable manner.
Patent EP-1662922-B1 (EP)
Inventor: ABDILLA RICHARD
IPC: A41H1/10
Filed: 2004-09-17
Granted: 2008-07-02
Abstract: A plurality of body sizers comprise sample garments for temporary wear made of a different material to a corresponding plurality of garments for long-term wear. Each of the garments for long-term wear is made to a predetermined size based on the size of a respective one of the body sizers. The most appropriately sized one of the garments for long-term wear may be selected by gauging which of the body sizers is the best match to the actual size of at least part of a person's body. A body sizer comprises a sample garment for temporary wear formed into a single integral piece and comprises means for indicating a plurality of different predetermined sizes on which the sizes of a corresponding plurality of garments for long-term wear are based.
Patent EP-1691624-B1 (EP)
Inventor: JUDGE DAVID JOHN
IPC: A23G9/20
Filed: 2004-10-27
Granted: 2010-09-22
Abstract: A frozen aerated confection comprising freezing point depressants in a total amount of 26-40% weight by weight, the freezing point depressants having a mean number average molecular weight of less than or equal to 320, characterized in that the confection has an extensibility of at least 30% at -18° C.
Patent EP-1698440-B1 (EP)
Inventor: TAKENAKA TORU
IPC: B25J13/00
Filed: 2004-11-29
Granted: 2011-10-12
Abstract: Ground contact sections (10) of a mobile body (1) (mobile robot) having three or more ground contact sections (10) are classified into a tree structure such that each of the ground contact sections (10) is a leaf node and that an intermediate section is present between the leaf node and a root node having all the leaf nodes as descendent nodes. For each node (C-th node) having child nodes, the amounts of correction of target relative heights of ground contact sections (10) of the C-th node are determined. The above determination is made such that a relative relationship between an actual floor reaction force of each child node of the C-th node approaches a target floor reaction force of each child node of the C-th node. Joints of the mobile body (1) are operated to satisfy the target relative heights obtained by composing the correction amounts.
Patent EP-1820130-B1 (EP)
Inventor: RIVIERE-CAZEAUX LIONEL
IPC: G06F17/50
Filed: 2004-11-30
Granted: 2011-09-14
Abstract: At a particular stage in design of an integrated circuit, DFM improvements are identified which might conflict with design requirements applicable during a subsequent stage in the design flow. These DFM improvements are “reserved” that is, they are not implemented right away. However, an instance of a DFM-optimized version of this portion of the design is generated, characterized and stored. Meta information is associated with the reserved DFM improvements, for example locations in the design which correspond to the reserved DFM improvements are tagged. If, after the subsequent stage in the design flow, processing of the meta-information (tags) shows that the reserved DFM improvement does not actually conflict with the potentially-conflicting design requirement, the corresponding reserved DFM improvement is implemented, for example, by swapping-in the stored instance of the DFM-optimized version of this portion of the design.
Patent EP-1692458-B1 (EP)
Inventor: MUENZER ADOLF
IPC: G01B11/02
Filed: 2004-12-10
Granted: 2009-08-12
Abstract: A method for measuring pyramid size of pyramids outwardly extending on a textured surface of an object, which method involves emitting from a light source a light beam along a first direction onto a region of the textured surface, measuring an intensity of light received from that region along a second direction, and processing the measured intensity to obtain an average size of pyramids; and a device suitable for measuring pyramid size according to the method.
Patent EP-1699969-B1 (EP)
Inventor: ACKERMANN UWE
IPC: D06F58/04
Filed: 2004-12-23
Granted: 2008-03-12
Abstract: A drying basket for a clothes dryer, comprising a longitudinal support and a wire basket fastened thereto. A connecting device is integrally configured on the longitudinal support and can be engaged with an opening provided on the clothes dryer. For this purpose, an opening is provided on the clothes dryer in a section of the clothes dryer housing, with which the connecting device of a drying basket can be engaged.
Patent EP-1616878-B1 (EP)
Inventor: DESNOYERS LUC
IPC: C12N15/62
Filed: 2000-03-01
Granted: 2008-12-10
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent EP-1619818-B1 (EP)
Inventor: COURONNE SYLVIE
IPC: H04L7/00
Filed: 2005-07-22
Granted: 2010-03-10
Abstract: A wireless localizing system (10) has a reference cycle transmitter (RCT) (12), locally distributed base stations (14) and mobile devices (16) waiting to be localized, i.e. for fixing their position. A low-jitter cycle signal is generated centrally in the RCT. A reference cycle transmission signal is then generated from a reference cycle. Independent claims are also included for the following: (A) A method for deriving a regenerated reference cycle from a reference cycle transmission signal; (B) and for a bases station for a device for deriving a regenerated reference cycle from a reference cycle transmission signal.
Patent EP-1608119-B1 (EP)
Inventor: BINDER YEHUDA
IPC: H03K17/16
Filed: 2001-09-12
Granted: 2008-11-05
Abstract: A communication system (50) for concurrently carrying multiple distinct signals over multiple transmission-line segments, each having at least two conductors, comprises a first (15a, 15b) transmission-line segment carrying a first signal and a second (15c, 15d) transmission-line segment carrying a second signal distinct from the first signal. The first and second transmission-line segments are connected to each other at a single connection point (51a, 51b) to which a termination device (30) is connected. The termination device is operative to stop the first signal to pass to the second transmission-line segment, and to stop the second signal to pass to the first transmission-line segment.
Patent EP-1618889-B1 (EP)
Inventor: D HONDT ERIK
IPC: A61K39/00
Filed: 2000-09-27
Granted: 2011-02-23
Abstract: The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also provided are methods for preparing the vaccines.
Patent EP-1575067-B1 (EP)
Inventor: FERRUCCIO DIANIN
IPC: H01H31/28
Filed: 2005-03-08
Granted: 2006-09-27
Abstract: The switch has a fixed contact (4) with smaller dimension and electrically connected to a movable contact that has curved arms (2, 3) forming a branch. The contact (4) is engaged between a pair of fingers (21, 31), in closing position of the switch. A clevis and a spacer are connected to ends of the arms to permit lever effect that amplifies electro-dynamic pinch-off exerted on the contact (4) by the fingers.