baber/WOPTO huggingface dataset:
Patent EP-2203439-A1 (EP)
Inventor: CID-NUNEZ JOSE MARIA
IPC: C07D493/10
Filed: 2008-09-12
Abstract: The present invention relates to novel compounds, in particular novel pyridinone derivatives according to Formula (I) wherein all radicals are as defined in the application and claims. The compounds according to the invention are positive allosteric modulators of metabotropic receptors - subtype 2 ('mGluR2') which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. In particular, such diseases are central nervous system disorders selected from the group of anxiety, schizophrenia, migraine, depression, and epilepsy. The invention is also directed to pharmaceutical compositions and processes to prepare such compounds and compositions, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR2 is involved.
Patent EP-2191308-A1 (EP)
Inventor: SAHLIN JENNIFER J
IPC: B32B7/02
Filed: 2008-08-28
Abstract: A flexible light guide including a material having a tensile modulus of about 1 MPa to about 70 MPa, an absorbance in the visible spectrum of less than about 0.0279 cm- 1, a refractive index of about 1.35 to about 1.65, and a thickness of about 50 microns to about 700 microns.
Patent EP-2187197-A1 (EP)
Inventor: WATANABE NAOKI
IPC: G01Q30/04
Filed: 2008-10-22
Abstract: A controller (21) of a cantilever evaluation system (20) calculates a stream function value Èx(x, y; t + 1) and vorticity Éz(x, y; t + 1) at a subsequent time step t + 1 using boundary conditions according to displacement h(z; t) of a cantilever (C) and velocity h/t(z; t), a stream function value Èz(x, y; t) and vorticity Éz(x, y; t) in two-dimensional planes (S2-3). The controller (21) uses the calculated stream function value Èz(x, y) and vorticity Éz(x, y) to calculate a fluid drag force (Fliq) acting on the cantilever (C) (S2-6). The controller (21) substitutes the calculated fluid drag force (Fliq) into a displacement calculation equation (6) to calculate the displacement h(z; t + 1) of the one-dimensional beam at the subsequent time step t + 1 (S3-2). The controller (21) repeats such calculation for each grid point and further repeats it at each time step.
Patent EP-2214608-A1 (EP)
Inventor: HIGHLEY BRIAN
IPC: A61F2/16
Filed: 2008-11-07
Abstract: An ocular implantation device comprises a housing having a longitudinal axis, a needle configured to receive an implant, and a plunger and a rod operatively coupled together. The plunger and the rod are disposed in the housing and are collectively, translationally moveable along the longitudinal axis of housing. The rod is configured to be receivable within at least a portion of the needle to enable the rod to move an implant therethrough. An actuator is operatively engaged with the plunger such that movement of the actuator in a direction aligned with the longitudinal axis of the housing results in translational movement of the plunger and the rod along the longitudinal axis of the housing in order to deliver the implant through the needle to a target site. An alternative embodiment of the device uses a retractable needle to deliver the implant.
Patent EP-2208031-A1 (EP)
Title: Radiometrisches zwei-draht-messgerät zur messung des füllstandes
Inventor: DAMM HARTMUT
IPC: G01F23/288
Filed: 2008-11-07
Abstract: Es ist ein radiometrisches Messgerät zur Messung einer physikalischen Messgröße eines in einem Behälter (3) befindlichen Füllguts (1) und zur Ausgabe eines Messsignals, das einem gemessenen Messwert der physikalischen Messgröße entspricht, beschrieben, das über ein einziges Leitungspaar (17) verfügt, über das die Energieversorgung des gesamten Messgeräts erfolgt, und über das die Übertragung des Messsignals erfolgt, mit einem radioaktiven Strahler (5), der im Betrieb radioaktive Strahlung durch den Behälter (3) sendet, einem Detektor (7) mit einem Szintillator (9) und einem Photomultplier (11), der dazu dient eine durch den Behälter (3) hindurch dringende von der zu messenden physikalischen Messgröße abhängige Strahlungsintensität zu detektieren und in ein elektrisches Ausgangssignal (N) umzuwandeln, einer Messgerätelektronik (15), die dazu dient anhand des elektrischen Ausgangssignals (N) des Detektors (7) das Messsignal (M) zu erzeugen und über das Leitungspaar (17) zur Verfügung zu stellen, einem über das Leitungspaar (17) gespeisten Energiespeicher (27), einer Steuerung (45), die in Abhängigkeit von einer über das Leitungspaar (17) und den Energiespeicher (27) zur Verfügung stehenden Energie Messphasen auslöst, während denen das Messgerät die physikalische Messgröße misst, und die den Photomultiplier (11) ausschließlich während der Messphasen in Betrieb nimmt, wobei für den Betrieb des Photomultipliers (11) erforderliche hohe Spannungen während der Messphasen mittels einer Hochspannungskaskade (31) erzeugt werden.
Patent EP-2213309-A1 (EP)
Inventor: KUMON HIROMI
IPC: A61K35/761
Filed: 2008-11-05
Abstract: The present invention provides a drug capable of causing cancer cells to restore anticancer drug sensitivity in cases in which cancer has acquired resistance to an anticancer drug and inducing cell death in cancer cells. The present invention specifically provides a cancer cell death inducing agent comprising REIC/Dkk-3 DNA as an active ingredient and having effects of potentiating an anticancer drug for cancer cells having anticancer drug resistance.
Patent EP-2179335-A1 (EP)
Title: Circuit de communication électrique avec diagnostic de dérivation
Inventor: KITCHENER RENATO
IPC: H04L69/40
Filed: 2008-11-14
Abstract: L'invention porte sur un circuit de communication électrique comprenant une alimentation électrique ; une section de ligne réseau, une section de dérivation ; des moyens d'isolation disposés entre la section de ligne réseau et la section de dérivation ; un appareil de diagnostic connecté à la section de ligne réseau ; et un dispositif de terrain connecté à la section de dérivation. Le dispositif de terrain est apte à envoyer des signaux de données sur le circuit de communication, lesquels signaux de données comprennent une ou plusieurs fonctions de base. Le circuit de communication et/ou les signaux de données fonctionnent selon un ou plusieurs paramètres de fonctionnement normal prédéterminés. L'appareil de diagnostic est apte à détecter une ou plusieurs violations prédéterminées des paramètres de fonctionnement normal. Un module de diagnostic de dérivation est connecté à la section de dérivation et apte à surveiller des caractéristiques électriques de la section de dérivation. Le module de diagnostic de dérivation comporte des moyens d'interférence aptes à interférer avec le circuit de communication et/ou avec les signaux de données envoyés sur celui-ci, de sorte que les une ou plusieurs violations prédéterminées des paramètres de fonctionnement normal soient détectables par l'appareil de diagnostic sans que les une ou plusieurs fonctions de base des signaux de données ne soient affectées. En cas de détection d'un ou de plusieurs événements électriques prédéterminés dans la section de dérivation, le module de diagnostic de dérivation est également apte à activer les moyens d'interférence.
Patent EP-2226326-A1 (EP)
Inventor: SAKUMA ATSUSHI
IPC: C07F7/00
Filed: 2008-12-02
Abstract: [Problem] To provide a preparation process by which an organic alkali metal compound is obtained in a high yield and a process for preparing an organic transition metal compound using the organic alkali metal compound. [Means to solve the problem] A process for preparing an organic alkali metal compound, which is  characterized by  adding a compound represented by the following formula (2) in the reaction of an active proton-containing compound represented by the following formula (1) with an alkali metal compound.
       
     In the formula (1), R is a hydrocarbon group or an amino group and may contain a halogen atom, a silicon atom, an oxygen atom or a nitrogen atom, H is an active proton, and p is the number of hydrogen atoms abstracted in the reaction with the alkali metal compound.
       
     In the formula (2), R a  to R c  are each an atom or a group selected from a hydrogen atom, a hydrocarbon group, a heteroatom-containing group and a silicon-containing group and may be the same as or different from each other, and the neighboring substituents may be bonded to each other to form a ring.
Patent EP-2233717-A1 (EP)
Inventor: MARUTANI YOUICHI
IPC: F02B23/02
Filed: 2008-11-05
Abstract: In a diesel engine 1 with a fuel injection valve 5 for injection of fuel into a combustion chamber 6 to produce sprays 7 in the chamber 6, an axis L1 of the valve 5 is deviated radially outwardly of an axis L2 of a cylinder 2, so that the valve 5 is positioned close to an inner periphery of the cylinder 2. Nozzle holes 5a of the valve 5 are grouped into two groups with respect to a line formed by connecting, in plan view, the axis L1 with the axis L2. The sprays 7 injected from the nozzle holes 5a advance in a fan-like manner in the plan view and strike against the inner periphery of the cylinder 2 on a side away from the valve 5.
Patent EP-2227096-A1 (EP)
Title: Produits céréaliers comportant une quantité non édulcorante d'un édulcorant puissant
Inventor: MCARDLE RICHARD
IPC: A23L27/30
Filed: 2008-11-26
Abstract: Cette invention concerne des produits céréaliers comestibles, par exemple des céréales, des flocons d'avoine, des barres d'encas, etc., comprenant au moins un constituant céréalier et une quantité non édulcorante d'au moins un édulcorant puissant. La quantité non édulcorante de l'édulcorant puissant peut comprendre un édulcorant puissant naturel, un édulcorant puissant artificiel, ou un mélange des deux. La quantité non édulcorante de l'édulcorant puissant peut modifier le goût du produit céréalier comestible en réduisant ou en éliminant une ou plusieurs des caractéristiques gustatives indésirables, en créant ou en augmentant une ou plusieurs des caractéristiques gustatives désirables, ou une association des deux.
Patent EP-2342808-A1 (EP)
Inventor: SVENSSON JAN R
IPC: H02J3/18
Filed: 2008-11-07
Abstract: L'invention porte sur un convertisseur à cellules reliées en chaînes (16) comprenant une ou plusieurs phases S1, S2, S3. La ou les phases S1, S2, S3 comprennent chacune une ou plusieurs cellules de convertisseur connectées en série 20, 21, 22, 23; 30, 31, 32, 33; 40, 41, 42, 43. Le convertisseur à cellules reliées en chaînes (16) est caractérisé par une source d'alimentation (18) connectée à une cellule de convertisseur (20, 21, 22, 23; 30, 31, 32, 33; 40, 41, 42, 43) de l'une des une ou plusieurs phases S1, S2, S3. Un démarrage économique du convertisseur est décrit. L'invention porte également sur un procédé et un système compensateur statique correspondants.
Patent EP-2372132-A1 (EP)
Inventor: SANO KEISUKE
IPC: F02D45/00
Filed: 2008-12-26
Abstract: The present invention has its object to provide a control apparatus for an internal combustion engine including a variable valve operating mechanism which is capable of accurately and effectively identifying an abnormality-occurring cylinder during operation while preventing the deterioration of a catalyst. 
     A fuel injection valve 26 which is capable of injecting fuel for each cylinder is provided. Variable valve operating mechanisms 18 and 20 which is capable of halting the operation of the intake and exhaust valves in the closed state for each cylinder are provided. An abnormality evaluation index value is acquired during the operation of the internal combustion engine 10 and, based on the abnormality evaluation index value, an abnormality which has occurred in at least one cylinder in the internal combustion engine is detected. When the abnormality is detected, a cylinder halting to perform the halting of fuel supply and the halting of the valve operation in the closed state is executed with a first partial cylinder made up of at least two cylinders as the target. After the cylinder halting, with the cylinder to be halted being changed, a cylinder halting is executed with a second partial cylinder made up of at least one cylinder as the target. Based on the change in the abnormality evaluation index value associated with the changing of the cylinder to be halted, the abnormality-occurring cylinder is identified.
Patent EP-2366397-A1 (EP)
Inventor: KIMURA YUKO
IPC: A61K31/727
Filed: 2008-12-05
Abstract: A catheter lock solution which is a catheter lock preparation having a bacteriostatic property at physiological osmotic pressure without practically containing a bacteriostatic component such as a preservative, an antimicrobial agent, or an antibiotic and having high safety,  characterized in that  the preparation contains a weak acid having an acid dissociation constant (pKa) of 3.0 to 6.5 as a buffer, a pH of the solution is less than 6.0, preferably from 3.0 to about 5.5, an osmotic pressure ratio is from 0.5 to 3.0, and a pH change (variation) can be suppressed to less than the 6.0 with the weak acid, and a container containing the catheter lock solution.
Patent EP-2107628-A1 (EP)
Inventor: TANAHASHI HIDEAKI
IPC: H01M8/02
Filed: 2009-04-03
Abstract: A fuel cell module includes: an electrode member (2) having a membrane electrode assembly (20), which is formed from an electrolyte membrane (22) and a pair of electrode catalyst layers (23a,23b) that is disposed on both sides of the electrolyte membrane (22) in the thickness direction, and having a pair of porous layers (21a,21b) disposed on both sides of the membrane electrode assembly (20) in the thickness direction; a separator (3) disposed layered on the electrode member (2) so as to contact at least one of the porous layers (21a,21b); and an adhesive rubber member (4) sealing a peripheral edge portion of the electrode member (2), wherein the electrode member (2) and the separator (3) are integrated by the adhesive rubber member (4), and a tensile product of the adhesive rubber member is 1,500 MPa·% or more.
Patent EP-2111813-A1 (EP)
Inventor: MCKENNA NICOLE
IPC: A61B19/00
Filed: 2009-04-21
Abstract: A jaw angle detection system for an end effector assembly includes a first electrical contact that connects to a first jaw member and connects to a generator. A sensor connects to a second jaw member (or an actuator) and connects to the generator, and configured to move relative to the first electrical contact upon movement of the second jaw member (or the actuator) when the first and second jaw members are moved to close about tissue disposed therebetween. Information relating to the position of the sensor relative to the first electrical contact is relayed back to the generator to determine an angle between the first and second jaw members.
Patent EP-2062749-A1 (EP)
Inventor: RE FIORENTIN STEFANO
IPC: B60C9/18
Filed: 2004-06-15
Abstract: A tyre (3) for vehicles, which does not require pressurisation by means of a pressurised fluid, has a tread (16), two sidewalls (15), and two beads (8) attached to a wheel rim (2) made of elastomer material; the tyre is provided with at least one tubular reinforcement body (18) which is associated with the tread; each of the sidewalls have a respective homogeneous resilient annular membrane (24), a straight generatrix of which forms an angle (A) other than 90° with the axis (13) of the tyre (3); outer grooves (22) of the tread communicate with the interior of the tyre via a plurality of radial passages (20,21).
Patent EP-2233824-A1 (EP)
Inventor: RUUD ALAN J
IPC: F21V23/06
Filed: 2009-03-25
Abstract: A low-voltage LED lighting system and method for installation thereof in which the system includes: (a) at least one LED lighting fixture (20) each having one or more LEDs; (b) at least one remotely-located power driver (12); and (c) interconnections between the at least one LED fixture (20) and the at least one driver (12) using communication network cabling (62) and standard 8P8C network connectors (18). Preferred lighting fixtures (20) are recessed lighting fixtures adapted for ceiling mounting.
Patent EP-2112636-A1 (EP)
Inventor: SATO NAOKAZU
IPC: G07G1/01
Filed: 2009-04-20
Abstract: A scanner unit reads code information attached to a commodity. A RAM stores the code information read by the scanner unit as commodity-for-purchase information. The scanner unit, to confirm whether the commodity-for-purchase information stored in the RAM is correct, the scanner unit reads the code information of one part of the commodity-for-purchase. A CPU switches from reading for storage to reading for confirmation. It is determined whether information contained in the code information read by the scanner unit is stored in the RAM. A display displays a result of the determination.
Patent EP-2116258-A1 (EP)
Inventor: CUA DANIEL J
IPC: A61P27/00
Filed: 2006-08-30
Abstract: Drug products for use in treating autoimmune ocular inflammatory disease are disclosed, which involve administration of agents that antagonize one or both of IL-17 and IL-23 activity.
Patent EP-2116524-A1 (EP)
Inventor: STRELCHENOK OLEG
IPC: A61K31/203
Filed: 2002-03-05
Abstract: This invention relates to the synthesis of sodium salts of retinoyls derivatives, capable of potentiating the efficacy of therapeutically active compounds, for example cytotoxic compounds used in the treatment of cancer. These compounds have been shown to increase the pharmacological activity of a conventional paclitaxel formulation and to make it possible to manufacture a new formulation of paclitaxel, exhibiting improved solubility, improved storage properties, and increased therapeutic efficacy as shown in the enclosed examples.
Patent EP-2301374-A1 (EP)
Inventor: XU YUANZHI
IPC: G09F3/00
Filed: 2009-11-05
Abstract: The present invention discloses a kid identification wristband, which comprises a clip (1) and a band (2), wherein the clip (1) consists of a lid part (4) connected to a bottom part (3) through a connecting part (5). In the center of the bottom part (3) a positioning column (10) is provided, with two squeezing parts set symmetrically at the two sides of the bottom part (3). Retaining pawls (12) are provided on the lid part (4), and two inserting parts (6) with grooves (9) are disposed symmetrically at the two sides of the lid part (4) corresponding to the protruding parts (8) provided on said squeezing parts. An opening (13) is provided at the connecting part (5), and another narrow opening (14) is provided on the bottom part (3) some distance away from the connecting part (5). The band (2) is fastened to the clip (1) in such a way that one end of the band is fixed by the positioning column (10) and the other free end of band (2) passes through the narrow opening (14) of the bottom part and then the opening (13) of the connecting part (5) and is fastened between the bottom part (3) and the lid part (4). The advantages of the present invention are that the identification band can be fastened firmly and can be opened easily with merely two fingers as well as being easy and safe to operate.
Patent EP-2189358-A1 (EP)
Inventor: LU YEN-HO
IPC: B62J6/00
Filed: 2009-11-19
Abstract: This invention proposes a turning-light integrated grip for bikes. Its main features comprises: (1) An invisible wiring is hided inside the grip (10), and also (2) The turning signal light module is hided and protected inside a corresponding outer ring (30) so that aesthetic merits can be reached. (3) Automatic power-off electrical function makes the product more practical for uses. The whole invention helps to enhance the safety of bike riding, and aforementioned features help the product to be more practically for use and marketing.
Patent EP-2189311-A1 (EP)
Inventor: LE GOURVELLEC FRANCOIS
IPC: B60G13/00
Filed: 2009-11-23
Abstract: The axle has a suspension arm and another suspension arm (20) oscillating in a vertical plane around an axis, and a hub carrier (24) that is provided at a rear, where the hub-carrier supports a rear wheel (34). Each suspension arm has an opening that is vertical to a closed contour, located in a width of the arm. Each arm is passed through a hydraulic damper (10), where the base of the damper is located at the suspension arms. A reinforcement tube (30) is passed through the opening. The latter arm has a longitudinal body (22) connecting a front ring (4) to the hub carrier.
Patent EP-2172465-A1 (EP)
Inventor: GRAMMENOS WASSILIOS
IPC: C07D401/04
Filed: 2005-07-22
Abstract: 2-Pyridyl pyrimidine derivatives (I) are new. 2-Pyridyl pyrimidine derivatives of formula (I) and their salts are new. k : 0-3; m : 0-5; n : 1-5; R 1>halo, OH, CN, NO 2, 1-4C (halo)alkyl, 104C (halo)alkoxy, 2-4C alkenyl, 2-4C alkynyl, 3-8C cycloalkyl, (1-4C)alkoxy(1-4C)alkyl, NH 2, phenoxy (optionally substituted with halo or 1-4C alkyl), NHR, NRR, C(Ra)=NORb, SO pA 1> or COA 2>; or R 1>+R 1>1-4C (halo)alkylenedioxy; R : 1-4C alkyl or 1-4C alkylcarbonyl; Ra : H or 1-4C alkyl; Rb : 1-4C alkyl, 3-4C alkenyl or 3-4C alkynyl; p : 0-2; A 1>1-4C alkyl, or also NH 2, 1-4C alkylamino or di(1-4C alkyl)amino when p = 2; A 2>H, OH, 1-4C alkyl, 1-4C alkylamino, di(1-4C alkyl)amino, 2-4C alkenyl or 1-4C (halo)alkoxy; R 2>1-4C haloalkyl, 1-4C (halo)alkoxy, OH, halo, CN or NO 2, or R 2> can be H or 1-4C alkyl if n = 3-5 and/or k = 1-3 and/or at least one R 1> is other than halo, 1-4C (halo)alkyl and 1-4C alkoxy; and R 3>1-4C alkyl. An independent claim is also included for controlling phytopathogenic fungi by treating the fungi, or materials, plants, soil or seeds to be protected from fungal attack, with a compound (I). [Image] ACTIVITY : Plant antifungal. In a protective test against Alternaria solani on tomato plants, plants treated with 2-(5-methyl-6-phenyl-2-pyridyl)-4,5-pentamethylene-pyrimidine (250 ppm) suffered no attack, whereas 90% of untreated plants were attacked. MECHANISM OF ACTION : None given.
Patent EP-2204162-A1 (EP)
Inventor: SIMONNET JEAN-THIERRY
IPC: A61Q19/08
Filed: 2009-12-30
Abstract: Cosmetic use of at least one monosaccharide comprising mannose, and/or rhamnose to reduce or prevent the signs of skin aging or its appendages, is claimed. (1) a composition comprising the monosaccharide comprising mannose, and/or rhamnose, in a medium, where the composition does not comprise a tensioning agent and does not include the combination of xylitol and mannitol; and (2) a device comprising the monosaccharide comprising mannose and/or rhamnose, where the device is adapted for intraepidermal, intradermal and/or subcutaneously injection. ACTIVITY : Dermatological; Endocrine-Gen. MECHANISM OF ACTION : Collagen synthesis stimulator.
Patent EP-2116198-A1 (EP)
Inventor: VIOLA FRANK
IPC: A61B17/072
Filed: 2009-05-08
Abstract: The present disclosure relates to surgical fastener applying apparatus and the application of variable compression to tissue. More specifically, the presently disclosed surgical fastener applying apparatus act to limit the flow of blood through tissue immediately adjacent a cut-line formed therein to effectuate hemostasis, while maximizing the flow of blood through tissue more removed from the cut-line to limit unnecessary necrosis. In one embodiment, a surgical fastener applying apparatus is disclosed having a tool assembly coupled to a distal end thereof with first and second jaws respectively including an anvil and a surgical fastener cartridge. The surgical fastener cartridge includes, among other things, angled pushers that engage surgical fasteners of varying lengths.