Patent SG-11201908509T-A (SG)
Title: Biosensors for biological or chemical analysis and methods of manufacturing the same
Inventor: ZHONG CHENG FRANK
IPC: H01L21/8238
Filed: 2018-03-19
Abstract: 133-1 133B 160 165 170 ,-120A -J20 --120B 114 900 112 111 110 FIG. 9 :: 7 ,:antatgan 115 113 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 27 September 2018 (27.09.2018) WIP0 I PCT ill 1111u°11111DIVIIl °nolo mu oil iflo oimIE (10) International Publication Number WO 2018/175341 Al (51) International Patent Classification: HOlL 27/146 (2006.01) GO1N 21/64 (2006.01) HOlL 21/8238 (2006.01) GO1N 21/76 (2006.01) (21) International Application Number: PCT/US2018/023176 (22) International Filing Date: 19 March 2018 (19.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/473,970 20 March 2017 (20.03.2017) US (71) Applicant: COMPLETE GENOMICS, INC. [US/US]; 2904 Orchard Parkway, San Jose, California 95134 (US). (72) Inventors: ZHONG, Cheng Frank; c/o Complete Ge- nomics, Inc., 2904 Orchard Parkway, San Jose, California 95134 (US). LI, Shifeng; c/o Complete Genomics, Inc., 2904 Orchard Parkway, San Jose, California 95134 (US). (74) Agent: KAO, Dah-Bin et al.; Kilpatrick Townsend & Stockton LLP, Mailstop: IP Docketing - 22, 1100 Peachtree Street, Suite 2800, Atlanta, Georgia 30309 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (54) Title: BIOSENSORS FOR BIOLOGICAL OR CHEMICAL ANALYSIS AND METHODS OF MANUFACTURING THE SAME (57) : Embodiments of the invention provide an improved biosensor for biological or chemical analysis. According to embod- iments of the invention, backside illumination (BSI) complementary metal-oxide-semiconductor (CMOS) image sensors can be used to effectively analyze and measure fluorescence or chemiluminescence of a sample. This measured value can be used to help identify a sample. Embodiments of the invention also provide methods of manufacturing an improved biosensor for biological or chemical analysis and systems and methods of DNA sequencing. [Continued on next page] WO 2018/175341 Al 1111101110110101011E111MMOMOINIDEll100111110111110VOIMIE TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))