baber/WOPTO huggingface dataset:
Patent EC-SP088145-A (EC)
Title: Derivados bicíclicos como inhibidores de la cinasa p38
Inventor: ALMANSA ROSALES CARMEN
IPC: C07D209/46
Filed: 2008-01-28
Abstract: Nuevos derivados bicíclicos de fórmula I, donde los significados de los distintos sustituyentes son los indicados en la descripción. Estos compuestos son útiles como inhibidores de la cinasa p38.
Patent EC-SP088281-A (EC)
Inventor: JONES ROBERT M
IPC: C07D401/14
Filed: 2008-03-14
Abstract: The present invention relates to 4-[5-methyl-6-(2-methyl-pyridin-3-yloxy)-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester, pharmaceutically acceptable salts, solvates and hydrates thereof that are modulators of glucose metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity.
Patent EC-SP088982-A (EC)
Title: Métodos para tratar enfermedades autoinmunes utilizando una molécula de fusión taci-ig
Inventor: BROLY HERVE
IPC: A61K33/242
Filed: 2008-12-12
Abstract: En varias realizaciones, la presente invención suministra métodos y composiciones para el tratamiento de enfermedades autoinmunes, incluyendo artritis reumatoide, por ejemplo comprende la administración a un paciente que necesita de tal tratamiento una molécula de fusión TACI-Ig. En una realización la molécula de fusión TACI-Ig se administra en una cantidad suficiente para disminuir, suprimir o inhibir las funciones que inducen proliferación en BlyS y APRIL.
Patent EC-SP971998-A (EC)
Title: Desprendimiento controlado de esteroides del recubrimiento de azucar
Inventor: REGINALD BARCOMB JOSEPH
IPC: A61K9/36
Filed: 1997-01-15
Abstract: En una tableta farmacéutica que comprende una sustancia interna y un recubrimiento de azúcar, en el cual dicha sustancia contiene agentes no farmacéuticamente activos o uno o más agentes no esteroidales, farmacéuticamente activos que son convencionalmente administrados en conjunto con un esteroide hormonal, el mejoramiento que comprende la incorporación de un esteroide hormonal y un esteroide hormonal desprende el promediode control de la cantidad de celulosa micocristalina en dicho recubrimiento azúcar.
Patent EE-9900591-A (EE)
Inventor: MARCEL GEREBERNUS MARIA LUYCKX
IPC: C07D417/04
Filed: 1998-06-22
Abstract: This invention concerns compounds of formula (I), the N-oxide forms, the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof, wherein R<1> is hydrogen, C1-6alkyl, C1-6alkyloxy, C1-6alkylthio, amino, mono- or di(C1-6alkyl)amino, Ar<1>, Ar<1>-NH-, C3-6cycloalkyl, hydroxymethyl or benzyloxymethyl; R<2> and R<3> are hydrogen, or taken together may form a bivalent radical of formula -CH=CH-CH=CH-; R<4>, R<5> and R<6> are each independently selected from hydrogen, halo, C1-6alkyl, C1-6alkyloxy, trifluoromethyl, nitro, amino, cyano, azido, C1-6alkyloxyC1-6alkyl, C1-6alkylthio, C1-6alkyloxycarbonyl or Het<1>; or when R<4> and R<5> are adjacent to each other they may be taken together to form a radical of formula -CH=CH-CH=CH-; A is a bivalent radical of formula NR<7>, NR<7>-Alk<1>-X-, NR<7>-Alk<1>-X-Alk<2>-, O-Alk<1>-X-, O-Alk<1>-X-Alk<2>- or S-Alk<1>-X-; wherein X is a direct bond, -O-, -S-, C=O, -NR<8>- or Het<2>; R<7> is hydrogen, C1-6alkyl or Ar<2>methyl; R<8> is hydrogen, C1-6alkyl or Ar<2>methyl; Alk<1> is C1-6alkanediyl; Alk<2> is C1-4alkanediyl; Ar<1> and Ar<2> are optionally substituted phenyl; phenyl; Het<1> and Het<2> are optionally substituted heterocycles; having angiogenesis inhibiting activity; their preparation, compositions containing them and their use as a medicine.
Patent FI-20031371-A (FI)
Inventor: MIETTINEN ERKKI
IPC: H01F37/00
Filed: 2003-09-23
Abstract: An inductor arrangement for a frequency converter or corresponding electrical apparatus, the inductor arrangement comprising an input inductor coupled to the input side of the electrical apparatus and an output inductor (2) coupled to the output side of the apparatus, the input inductor comprising a core element (1) having yokes (7, 8) and columns, and several winding turns (3) for each phase formed around the core element (1). The output inductor (2) is provided in the inductor arrangement by placing a predetermined length of a conductor (4) of each phase in the output of said electrical apparatus adjacent to the core element (1) of the input inductor. <IMAGE>
Patent FI-20075434-A (FI)
Inventor: KOIVUSALMI EIJA
IPC: C07C/
Filed: 2007-06-11
Abstract: The invention relates to a process for producing saturated C5-C28 hydrocarbons, suitable as diesel fuels, kerosenes and gasolines, comprising the steps where feedstock derived from st starting material of biological origin, is subjected to a condensation step and subsequently subjected to a combined hydrodefunctionalization and isomerization step.
Patent GB-1050210-A (GB)
IPC: D04B1/02
Abstract: 1,050,210. Knitting machines; loop pile fabrics. AMES TEXTILE CORPORATION. Aug. 21, 1964 [Aug. 21, 1963], No. 34292/64. Addition to 990,075. Headings D1C and D1K. A circular knitting machine for the production of pile fabric has means for independantly measuring the loops of pile and the loops of body yarn. In one embodiment (Fig. 3) yarn measuring members 24', 25' are located in the cylinder of a machine and the bearded needles are located in the dial of the machine. In a second embodiment Fig. 4 (not shown), one set of yarn measuring members is replaced by a stitch wheel 100 of known type. In this embodiment the bearded needles are located in the cylinder of the machine. In a further embodiment Fig. 6 (not shown) the second set of yarn measuring instruments is replaced by a set of latch needles.
Patent GB-1054115-A (GB)
IPC: G11B17/14
Abstract: 1,054,115. Magazine spindles for automatic gramophones. GARRARD ENGINEERING Ltd. Oct. 17, 1963 [Oct. 17, 1962], No. 39362/62. Heading G5R. A magazine spindle for use with large-hole records, of the kind comprising an upper portion 1, Fig. 1, offset from a lower portion 2 to form a ledge 3 supporting the bottom record of a stack, and a horizontally disposed slide 6, 7 for ejecting a record, is characterized in that the ledge slopes downwardly. As shown in Fig. 2 the upper portion is provided with a slot 4 to form a shelf 5 for supporting the record above the bottom record on the side opposite the ledge 3. The slide is spring biased to the position shown in Fig. 1 with a pre-ejector portion 8 extending through the slot 4 flush with the upper portion of the spindle and a support portion 9 projecting outwardly to support the bottom record, the other end of the slide comprising a storage transfer portion 11 and an ejector portion 12 extending below the ledge 3. An ejector blade 13 is preferably arranged between portions 11 and 12 of the slide. An actuating lever 14 is coupled directly to the blade 13 and with lost motion to the slide. Initial movement of the actuating lever 14 by the cycling mechanism of a record changer normally causes the blade 13 to be inserted between the bottom record and the next record, and further movement of the lever moves the slide 6, 7 thereby withdrawing the support portion 9 and causing the ejector portion to move the bottom record off the ledge 3, the next record being moved on to the shelf 5 by the storage transfer portion 11. If the bottom record is too thick, the blade 13 will strike the wall of the record hole and moves the record in the direction of arrow 19, Fig. 5, displacing the slide against its spring, with the result that the record moves down the sloping portion 17 of the ledge 3 until the blade 13 can pass above it. To facilitate downward movement of the record the shelf 5 may be cut off along a chord parallel to the pre-ejector portion 8 of the slide, Fig. 8 (not shown). In addition the portion of shelf 5 that overhangs the lower spindle portion is sloped inwardly at its under side, and so is the upper portion 22 of the outer surface of the ejector portion of the slide, the lower portion being vertical for about the thickness of a record above the lower end of the shelf slope 17 to define more accurately the actual moment of ejection. If the bottom record is too thin, the blade 13 strikes the next record which is then held by friction between the blade 13 and the pre-ejector portion 8 of the slide; any slight downward movement is made good when the movement of the actuating lever 14 is reversed and the record slides up the slope 17 of the ledge.
Patent GB-1054922-A (GB)
IPC: B29C53/80
Abstract: 1,054,922. Making re-inforced plastic tubes. B.C.M. PLASTIC DEVELOPMENTS Ltd. July 11, 1963 [July 20, 1962], No. 27950/62. Heading F2P. [Also in Division D1] A pipe or tube is made by winding a composite fabric of glass or like fibres helically in layers on a mandrel 11 with the incorporation of molten synthetic resin, the tube then being rendered rigid by heat treatment, removed from the mandrel and cured. The fabric comprises inner and outer layers 1, 2 of side-by-side rovings of glass or like fibre which are fed between rollers 3, 4 together with an intermediate layer of a roving 6 which is fed zig-zag at the nip of the rollers by an eye 10, Fig. 1 (not shown) carried by a member 9 oscillated by levers 7, 8 which are actuated by a crank-pin and follower 12.
Patent GB-1056180-A (GB)
Abstract: 1,056,180. Potentiometric measurements. HITACHI Ltd. Nov.22, 1963 [NOV.26, 1962], No.46286/63. Heading G1U. Range changing facilities for a self balancing measuring potentiometer comprise a step variable resistor connected between the moving contact and the fixed terminal of the potentiometer P, the tap or switch S' of the step variable resistor being connected to the input signal source E 1 .  The signal E 1  from the step variable resistor and the signal E 1  are applied in opposition to the two inputs of a servo amplifier SA which controls a motor arrangement which effects automatic balancing of the potentiometer P. To avoid changes in sensitivity which will be involved in changing the divider ratio in this arrangement, a stepped resistor may be connected in series with E the tappings on the resistor being switched out by the switch S" which is coupled to the switch S'.
Patent GB-1228204-A (GB)
IPC: F42B10/34
Filed: 1968-09-06
Abstract: 1,228,204. Practice projectiles. DYNAMIT NOBEL A.G. 6 Sept., 1968 [6 Sept., 1967], No. 42656/68. Heading F3A. A practice projectile comprises a projectile body 2 having an axial bore extending throughout its length, and a discardable nose, e.g. of plastics material, having a core 3, the nose having an asymmetrical cross-section in relation to its longitudinal axis and/or a rearwardly open annular cavity 4 defined by the core 3 and a rupturable wall 5. The nose is rendered asymmetrical by means of a bore 8 and is a snap-fit on the projectile body 2. The core 3 may be hollow and the wall 5 of the nose can be strengthened with radial ribs. Upon firing, propellant gases cause the nose to be discarded by the projectile body whereupon the asymmetry of the nose causes the latter to be diverted from the trajectory of the projectile body and/or the propellant gases cause the wall 5 and core 3 to rupture to produce particles of shorter range than the projectile body.
Patent GB-1229710-A (GB)
IPC: F01L25/08
Filed: 1969-03-11
Abstract: 1,229,710. Valves. F. FISCHBACH. 11 March, 1969 [23 March, 1968], No. 12839/69. Heading F2V. Supplying or venting of either one or two working ports 3 and 5, is effected by connecting these either to a supply port 4 or to a venting chamber 2 having an outlet 6 leading therefrom, respectively, with both the direction of fluid flow as well as the quantity of such flow being controlled by a landed spool 8. The spool is maintained in a central or neutral position shown by the provision of two springs 11a and 11b which act between stops 12a, 12b and slotted supports 10a, 10b respectively, whilst movement of the spool towards the right, as seen in the drawing (Fig. 2, not shown), is effected by energizing a solenoid 14a which in turn attracts an armature 15a attached to the lefthand end of the spool, the degree of communication between ports 4 and 5 and ports 3 and 6 being determined by an adjustable stop 17b. Similar limiting control is provided by an adjustable stop 17a which is engaged by armature 15a upon soleniod 14b being energized. In a modification (Figs. 3 and 4, not shown), the spool ends have shafts (22) extending therefrom and beyond the housing, with movement limitation being achieved by providing those portions of the shafts extending beyond the housing with adjustable nuts which engage the housing, actuation of the spool being effected by applying fluid pressure to the appropriate end of the spool.
Patent GB-1232021-A (GB)
IPC: F02M1/16
Filed: 1967-03-02
Abstract: 1,232,021. Spray carburetters; intake passages. STANDARD-TRIUMPH MOTOR CO. Ltd. May 30, 1968 [March 2, 1967], No. 9814/67. Heading F1B. Rich mixture formed in a port passage 12, Fig. 4, of a carburetter 22 is discharged axially at 36 into the flow of secondary air from the passage 11 of the carburetter. The carburetter 22 is identical with that described in Specification 1, 232, 022 and has a suction actuated piston controlling the air-flow through passage 11, a metering pin on the piston controlling the fuel jet opening into the passage 12. The mixture flow is controlled by a throttle valve situated near the flange 53 connected to the engine intake manifold and the portions 35, 52 of the mixture passage may be heated by jackets 54, 55, supplied with exhaust gas or hot water. A suction-actuated annular disc valve 41, Fig.3 supported by a spector 44 on a sleeve 43 slidable along the mixture nozzle 36, deflects the secondary air into a stream surrounding the tube 36. When valve 41 reaches the wider portion 47, part of the secondary air is diverted to flow along the wall of the mixture passage 42 to prevent fuel being deposited thereon. A streamlined member 48, supported by a flange 51, further guides the air-flow around the mixture stream from nozzle 36. A pair of carburetters may be combined, Fig. 5 (not shown).
Patent GB-1237942-A (GB)
IPC: C08G18/38
Filed: 1968-10-18
Abstract: 1,237,942. Aminoalkylphosphonates. STAUFFER CHEMICAL CO. 18 Oct., 1968 [20 Oct., 1967], No. 49434/68. Heading C2C. [Also in Division C3] Compounds of the formula in which R 1  and R 2  are alkyl, haloalkyl, hydroxyalkyl or aryl radicals; R 3  and R 4  are H, alkyl, cycloalkyl, aryl, carboxyl, alkylene or heterocyclic radicals; or R 3  and R 4  together may represent a cycloalkyl or cycloaliphatic ring, R 5 , R 6 , R 7  and R 8  are hydrogen, hydroalkyl, lower alkyl or alkylene radicals and R 9  is hydrogen, alkyl, hydroxyalkyl or aryl are prepared by reacting a compound of the formula with a #-hydroxy alkylamine of the formula and then reacting the product with an appropriate diester of a phosphonic acid in the presence of an available free water content of less than 0À75 mole of water. These compounds may be used as fire-retardant agents in polyurethane polymers.
Patent GB-1238424-A (GB)
IPC: H01Q25/02
Filed: 1969-07-10
Abstract: 1,238,424. Aerials; radar. MARCONI CO. Ltd. 4 March, 1970 [10 July, 1969], No. 34776/69. Headings H4A and H4D. A sum and difference aerial arrangement comprises an aerial array consisting of a plurality of pairs of aerial elements, the elements (a 1 , b 1 ), (a 2 , b 2 ), (a 3 , b 3 ), (a 4 , b 4 ) of each pair being symmetrically disposed with respect to a centre point P (about which the array may be rotated). Sum and difference combiners SD1, SD2, SD3, SD4 are each connected to the two elements of a different pair. The sum terminals of all the combiners are connected to an adder AD1, and their difference terminals are connected to another adder AD2. In a radar incorporating the array, the signal for transmission is normally applied to the adder AD1, and received signals are taken for utilization from both adders AD1 and AD2. The arrangement as described is stated to allow satisfactory adjustments to be made of side lobe levels for both radiation diagrams, corresponding respectively to the sum mode and the difference mode. The combiners SD1 to SD4 may be strip-line couplers or waveguide couplers, for example, of the H-plane folded magic-T type.
Patent GB-1251937-A (GB)
IPC: F27D15/02
Filed: 1970-10-06
Abstract: 1,251,937. Cooling material discharged from furnaces. WEDAG WESTFALIA DINNENDAHL GROPPEL A.G. 6 Oct., 1970 [6 Oct., 1969], No. 47417/70. Heading F4B.  A grate cooler 1 for material discharged from a rotary furnace 3 comprises an additional cover 6 above the roof 5 defining therewith a plenum chamber 8 open to the atmosphere through slots 7 and connected to a fan 10 through one or more pipes 9 said fan discharging through a pipe 11 into the front of the cooler. The cover 6 is effectively part of the burner platform 4 and is made of ribbed plates.
Patent GB-1252418-A (GB)
IPC: G03C7/305
Filed: 1967-11-24
Abstract: 1,252,418. Pyrazolotriazbles. KODAK Ltd. 21 Nov., 1968 [24 Nov., 1967], No. 53560/67. Heading C2C. The invention comprises compounds of the formulµ where R 1  is H, an esterified carboxy group or a group whichsplits off during colour development and R 2  is a group of the formula =CHR 3  which splits off during colour development wherein R 3  is alkyl, aralkyl or aryl and wherein the positions 3 and 6 may carry substituents conventionally employed for photographic colour couplers. The compounds may be prepared by ring closure of compounds of the formulµ where R 6 , R 7  and R 8  are alkyl, aralkyl, aryl which may be substituted or NHR 9  where R 9  is alkyl, aralky or aryl which may be substituted. The group COOR 8  may be hydrolysed to COOH which may be split off. A halogen atom or a sulpho or phenylthio group may be introduced at position 7 by treating with halogen, oleum or C 6 H 4 SCl respectively. A phenoxy group may be introduced at position 7 by treating a 7-Br compound with sodium phenate. Further substituent groups may be introduced by known methods.
Patent GB-1252569-A (GB)
IPC: H01J5/02
Filed: 1968-12-17
Abstract: 1,252,569. Ion sources. ASSOCIATED ELECTRICAL INDUSTRIES Ltd. 26 Nov., 1969 [17 Dec., 1968], No. 59940/68. Heading H1D. In an ion source for a mass spectrometer at least two different vaporized samples are introduced through separate inlets 17 into respective regions of an evacuable ionization chamber 10 in which the movement of the vaporized samples between the regions is restricted, for example by a partition 11, ions are produced in each region 12 by electron beam bombardment, and an electrode system 13, 14, 15 and 16 is provided to accelerate the ions so formed into anion beam 20 which contains ions from both or all the samples. As shown, the ion exit slit 14 may have tapered edges, and the edge of the partition 11 adjacent slit 14 may be similarly shaped. The formation of a single ion beam 20 may also be facilitated by shaping the repeller plates 13, one plate 13 being provided for each region and mounted insulated from each other on a ceramic support 21. The several ionizing electron beams may be derived from a single or separate cathodes, and the ionizing energies of the electron beams are preferably, though not necessarily, the same. Opposite edges of the ion exit slit 14 may be insulated from each other so that different potentials may be applied thereto to optimize the performance from each half of the source. Chamber 10 is continuously evacuated via ion exit slit 14 by a pump located outside the chamber. In an example, nitrogen and heptocosa fluoro tributylamine were the samples used.
Patent GB-1256609-A (GB)
IPC: D06P1/613
Filed: 1969-12-18
Abstract: 1,256,609. Dyeing wool/synthetic fibre mixtures. FARBWERKE HOECHST A.G. 18 Dec., 1969 [18 Dec., 1968], No. 61736/69. Heading DIB. Fibre mixtures of wool and synthetic hydrophobic fibres in which the synthetic fibres are dyed or printed with disperse dyes are treated during or after the dyeing or printing process with an aqueous solution or emulsion of a polyglycol ether compound of formula: in which n is 1 or 2, R is a hydroxy group or an organic radical having no more than 30 carbon atoms of a compound which contains 1 or 2 hydrogen atoms capable of reacting with ethylene oxide or propylene oxide and Y is an integer, X is an integer or zero, Z is an integer or zero, such that when n is 1 Y is at least 20 the sum of X and Z being at least 15, or when n is 2, Y is at least 10 and, the sum of X and Z is at least 7, the molecular weight of the compound not exceeding 7000. Synthetic fibres used are polyacrylonitrile, cellulose acetate and linear polyesters, the compounds as above being prepared from ethylene and propylene oxides, with saturated or unsaturated straight chain or branched monohydric aliphatic alcohols, alkane diol, primary or secondary alkylamine, a saturated or unsaturated aliphatic carboxylic acid or amide, a phenol, or a mono-ordialkyl-phenol. The treatment with the above compounds may be effected at 60 to 90‹C using 0.2 to 5 gms per litre of the compound. The treatment removes the disperse dye from the wool portion of the mixture.
Patent GB-1257319-A (GB)
IPC: G05B23/02
Filed: 1968-11-20
Abstract: 1,257,319. Phase controlled systems; secret transmission. GENERAL ELECTRIC CO. Ltd. 20 Feb., 1970 [20 Nov., 1968], No. 55172/68. Headings H3A and H4R. A circuit for determining, or providing a response dependent upon a time displacement T u  between two signals having the same random or quasi-random waveform, comprises an arrangement e.g. Hilbert Transform network 8, for imposing quadrature phase shifts between discrete components of the same frequency in a frequency band in the two signals without introducing any gain variation with frequency and a correlator 4 e.g. of a quadrant multiplier 5 and a low-pass filter 6, to provide a correlation signal having a characteristic which is an odd function of time displacement. The circuit also includes a timing network 3 controlled in dependence of said output signal to produce a time delay equal to that of a test network 2. The test network may correspond to the delay involved in a signal utilization path such as target receiver path delay in a radar, or a portion of the system loop in a complex processing plant. The two signals may be derived from a single analogue random generator 1 or from a single or two identical digital quasi-random generators 10, 11 as shown in Fig. 6 connected to band-pass filters 14, 15. The two generators 10, 11, may be used in a voice communication system comprising a unit 20 supplying a transmitter 21 with speech at a constant power level i.e. eliminating variations at a syllabic rate, the speech being superposed on the quasi-random analogue signal. The signal path between the filter 14 and the Hilbert transform network 17 constitutes the unknown time delay and the P output of 17 and Q output of 18 are applied to a correlator 19 to produce a signal to be applied to circuitry (not shown) to control clock generator 11 so that the time delay in signal path 13, 15, 18 equals the above unknown time delay. The Generator 13 is synchronized to the generator 12 and subtraction of the noise output from 15 at S yields a pure speech signal restored to its original power level by unit 22. The system may be used as part of an analogue or digital communication link with a digital link inserted between generator 12 and band-pass filter 14 and an analogue link inserted between separate parts of the band-pass filter 14.