baber/WOPTO huggingface dataset:
Patent AU-2021297248-A1 (AU)
Title: LNP compositions comprising mRNA therapeutics with extended half-life
Inventor: REID DAVID
IPC: A61K48/00
Filed: 2021-06-23
Abstract: The disclosure features a polynucleotide encoding a polypeptide, which polynucleotide comprises: a 5'UTR described herein; a coding region comprising a payload and a stop element described herein; and a 3'UTR described herein, and LNP compositions comprising the same. The polynucleotides and/or LNP compositions of the present disclosure can: increase the level and/or activity of the payload by increasing the half-life and/or duration of expression of the polynucleotide encoding the payload or of the payload polypeptide. Also disclosed herein are methods of treating a disease or disorder in a subject using the LNP compositions of the present disclosure.
Patent AU-2021310447-A1 (AU)
Title: System for loading liquid natural gas
Inventor: AOUN BERNARD
IPC: F17C9/00
Filed: 2021-07-15
Abstract: The present invention primarily relates to a loading system (1) configured to transfer a cryogenic fluid (3) from a storage vessel (2) into a receiving vessel (4), the loading system (1) comprising at least one element (17) for circulating the cryogenic fluid (3) in the liquid state which connects the storage vessel (2) to the receiving vessel (4), a processing and/or consumption unit (26) of the cryogenic fluid (3) in the gaseous state originating at least from the receiving vessel (4) and a return line (28) of the cryogenic fluid in the gaseous state which connects the receiving vessel (4) with the processing and/or consumption unit (26), characterised in that the loading system (1) comprises at least one cooling unit (36) of the cryogenic fluid (3) circulating towards the receiving vessel (4) in the circulation element (17), the cold generated by the cooling unit (36) resulting from an evaporation of the cryogenic fluid (3) coming from the storage vessel (2).
Patent AU-2021313472-A1 (AU)
Title: Methods and compositions for treating lung conditions
Inventor: LEBOVITS CHAIM
IPC: A61P31/14
Filed: 2021-07-20
Abstract: The present invention provides compositions comprising mesenchymal stem cells (MSCs) and/or exosomes derived therefrom, mesenchymal stem cells secreting neurotrophic factors (MSC-NTFs) and/or exosomes derived therefrom, and methods for their use in treating adverse lung conditions, such as Coronavims-related acute respiratory distress syndrome (ARDS).
Patent AU-2021346784-A1 (AU)
Title: Method for working a plot of land by a fleet of at least two agricultural robots
Inventor: HOELLINGER MARIE
IPC: A01B69/00
Filed: 2021-09-14
Abstract: The invention relates to a method for working a plot of land (P) simultaneously by at least two agricultural robots (R1, R2, Ri) operating autonomously and independently, in accordance with instructions and/or commands transmitted by a common central management and control system (SC). The method is characterised in that it consists in subdividing said plot of land (P) to be treated into at least two distinct work zones (Z1, Z2, Zj) and allocating each work zone (Z1, Z2, Zj) exclusively to one of the agricultural robots (R1, R2, Ri), at least during the working phase in question, the width (Lz) of the majority of the work zones (Z1, Z2, Zj) being equal to a multiple, greater than or equal to 1 and preferably an integer, of the working width (Lr) of the agricultural robot (R1, R2, Ri) to which it is exclusively allocated, and in that, during work on the plot of land (P), work zones (Z1, Z2, Zj) not yet worked are exclusively allocated to the various agricultural robots (R1, R2, Ri), respectively, in a gradual manner according to the completion of the work undertaken by the agricultural robots in the various work zones allocated to them.
Patent AU-2021347814-A1 (AU)
Title: Tes-based cationic lipids
Inventor: KARVE SHRIRANG
IPC: A61K48/00
Filed: 2021-09-22
Abstract: The present invention provides, in part, TES-based lipid compounds of Formula (la), and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.
Patent AU-2021358736-A1 (AU)
Title: New compounds and their use as therapeutically active substances in the treatment and/or prevention of diseases involving the retinal pigment epithelium
Inventor: STEGER MATTHIAS
IPC: A61P27/02
Filed: 2021-10-05
Abstract: A method of treating and/or preventing disease wherein retinal pigment epithelium, including administering compound of formula (I) or pharmaceutically acceptable salt, racemic mixture, corresponding enantiomer or, if applicable, corresponding diastereomer, wherein: X is either NH or O, R
Patent AU-2021379260-A1 (AU)
Title: Aerosol-generating system with improved electrical connector
Inventor: AW SZE CHIEK
IPC: H02J7/00
Filed: 2021-11-12
Abstract: An electrically operated aerosol-generating system (100), an electrically operated aerosol-generating device (101), a charging unit (103) for an electrically operated aerosol-generating system (100), and an electrical connector for an aerosol-generating system (100). The electrically operated aerosol-generating system (100) comprises an aerosol-generating device (101), a charging unit (103) configured to receive the aerosol-generating device (101) and a first connector part (1) and a second connector part (21). The aerosol-generating device (101) has one of the first connector part (1) and the second connector part (21), and the charging unit (103) has the other one of the first connector part (1) and the second connector part (21). The first connector part (1) comprises: a first electrical contact (3); a second electrical contact (4) substantially circumscribing the first electrical contact (3); and a third electrical contact (5) substantially circumscribing the second electrical contact (4). The second connector part (21) comprises: a face (26) and a projection (27) arranged substantially centrally in the face (6); a first electrical contact (23) arranged on the projection (27); a second electrical contact (24) arranged at the face (26), spaced radially outwardly from the first electrical contact (23); and a third electrical contact (25) arranged at the face (26), spaced radially outwardly from the second electrical contact (23). The first and second connector parts (1, 21) are arranged such that when the aerosol-generating device (101) is received by the charging unit (103) the first and second connector parts (1, 21) electrically engage. The electrical contacts of the first and second connector parts (1, 21) are arranged such that when the first and second connector parts electrically engage: the first electrical contact (3) of the first connector part (1) electrically engages the first electrical contact (23) of the second connector part (21); the second electrical contact (4) of the first connector part (1) electrically engages one of the second electrical contact (24) and the third electrical contact (25) of the second connector part (21); and the third electrical contact (5) of the first connector part (1) electrically engages the other one of the second electrical contact (24) and the third electrical contact (25) of the second connector part (21), regardless of the angular position of the second connector part (21) relative to the first connector part (1).
Patent AU-2021401741-A1 (AU)
Title: Macrocycles and their use
Inventor: CUI JINGRONG J
IPC: A61K45/06
Filed: 2021-12-16
Abstract: The present disclosure relates to macrocyclic compounds, pharmaceutical compositions containing macrocyclic compounds, and methods of using macrocyclic compounds to treat disease, such as cancer.
Patent WO-2023230643-A1 (WO)
Inventor: GALIL NADER
IPC: A63B23/14
Filed: 2022-06-01
Abstract: L'invention concerne un dispositif d'entraînement contre résistance portable (1), qui a un premier bras (2) et un second bras (3), ayant chacun une extrémité proximale (4, 5) et une extrémité distale (6, 7), les extrémités proximales (4, 5) des premier et second bras (2, 3) étant fixées de manière articulée l'une à l'autre à un point de pivot (8). Un élément de sollicitation (9) exerce une force s'opposant à une rotation pivotante des premier et second bras (2, 3) l'un par rapport à l'autre autour du point de pivot. Un limiteur de mouvement (10) limite de manière ajustable la quantité de rotation pivotante entre les premier et second bras (2, 3). Un dispositif d'ajustement de tension (11) ajuste la quantité de force exercée par l'élément de sollicitation (9).
Patent WO-2023028655-A1 (WO)
Inventor: ROUX SHAUN
IPC: A47J43/27
Filed: 2022-09-01
Abstract: A liquid container is disclosed for use with a pod sealed capsule for the mixing of a beverage. The liquid container includes a container body for containing a liquid fluid; and a lid connectable to the container body. The lid includes a lid lower body having a collar connectable to the container body, an outlet in fluid communication with the container body for egress of the beverage from the container body and a pod piercing structure extending inwardly relative to the collar for piercing the pod sealed capsule. The lid further includes a lid upper body connectable to the lid lower body. The lid upper body has a pod sealed capsule receptacle for receiving a pod sealed capsule therein and an actuating mechanism for pressing the pod sealed capsule against the pod piercing structure and releasing its contents into the liquid fluid of the container body.
Patent AU-2022200051-A1 (AU)
Title: Gaming machine having separated feature games
Inventor: SATTERLIE ERIC
IPC: G07F17/32
Filed: 2022-01-06
Abstract: A gaming machine having three displays of (1) five mechanical reels, (2) five video 
reels and (3) a single multi-slice wheel. Gaming interaction between the three displays 
provides a base game on the mechanical reels from which (1) a first spinning-reel-type bonus 
game is triggered and (2) a second wheel-type bonus game is triggered.  
18360627_1 (GHMatters) P108953.AU.2
Patent AU-2022200404-A1 (AU)
Title: Method of operating a ride and a ride
Inventor: GRABITZ CHRISTIAN
IPC: A63G33/00
Filed: 2022-01-21
Abstract: The present invention provides a packaging box, including a box body; the box body is provided 
with an insertable zone; a dashed hole is disposed at an edge of the insertable zone. The 
insertable zone is round and may be completely or partially separated from the box body; there 
is an insertable zone on the box body. The packaging box provided by the present invention 
has an insertable zone. The detecting personnel need not find out an extra tubular fixed seat for 
use. Meanwhile, a packaging box is used to replace a tubular fixed seat, reducing the use cost 
of the detecting apparatus. Moreover, each lysis tube can be inserted into respective packaging 
box; and each packaging box is corresponding to respective detecting apparatus. Therefore, it 
is not easy to cause the misuse of lysis tubes during loading and detection procedure, thereby 
avoiding wrong detection because the lysis tube is taken by mistake.
1/4 
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Fig.2
Patent AU-2022205989-A1 (AU)
Title: Neutralizing antibodies to il-17a, fusion proteins thereof, and uses thereof
Inventor: WHITE DANIEL
IPC: C07K16/18
Filed: 2022-01-10
Abstract: Disclosed are compositions and methods related to anti-IL-17A antibodies and antigen binding fragments thereof. Additionally provided are bi-specific binding proteins comprising the anti-IL-17A binding domains. Additionally provided are methods of use for the compounds and compositions described herein in the treatment of inflammatory diseases and ocular disorders.
Patent AU-2022220861-A1 (AU)
Title: Lateral flow assay with sample adequacy line
Inventor: REN HUIMIAO
IPC: G01N33/53
Filed: 2022-02-11
Abstract: Immunoassay devices, systems, and methods described herein measure the presence of analytes of interest in a sample, as well as the presence of sample adequacy markers in a sample. The sample adequacy markers allow for the assessment of the quality, quantity, and composition of the sample. In one aspect, the sample adequacy marker in the sample includes human albumin. In another aspect, the sample adequacy marker in the sample includes lactotransferrin. The immunoassay devices, systems, and methods are able to distinguish between samples that do not contain an analyte of interest, and samples that are of insufficient adequacy to obtain an accurate result. The immunoassay devices, systems, and methods described herein can be implemented as part of a clinical, laboratory, or at-home testing system.
Patent AU-2022229030-A1 (AU)
Title: A therapeutic massage device
Inventor: CARDEN BRADLEY
IPC: A61H15/02
Filed: 2022-03-03
Abstract: A massage device has a generally cylindrical body comprising an internal battery and controller for a plurality of light source elements. The body defines an exterior surface comprising the light source elements arranged in a matrix to emit light from a surface area of the surface.
Patent AU-2022241559-A1 (AU)
Title: Parenteral non-systemic administration of buffering agents for inhibiting metastasis of solid tumors, hyperpigmentation and gout
Inventor: SAND BRUCE J
IPC: A61P35/04
Filed: 2022-09-29
Abstract: Parenteral dosing (other than direct systemic dosing) of pH raising and other anti
metastasis agents alone or in combination is effective and overcomes disadvantages of 
intravenous and oral administration in the treatment of solid tumors, melasma and gout.
Patent AU-2022242243-A1 (AU)
Title: Hydrogen production apparatus
Inventor: MIYAURA TAKUTO
IPC: C01B3/30
Filed: 2022-02-21
Abstract: The hydrogen production device 100 is equipped with: a first heating furnace 110 having a first housing tank in which a fluidized bed of a catalyst including one or more of iron, nickel, copper, and aluminum is formed and a heat transfer tube provided within the first housing tank, through which a heating medium passes; a second heating furnace 120 having a burner for burning a fuel to generate a combustion exhaust gas and a second housing tank in which a fluidized bed of the catalyst discharged from the first heating furnace is formed by the combustion exhaust gas; and a pyrolysis furnace 140 having a third housing tank in which a fluidized bed of the catalyst discharged from the second heating furnace is formed by a raw material gas including a hydrocarbon.
Patent AU-2022245228-A1 (AU)
Title: Mattress assemblies
Inventor: WHATCOTT RUSSELL B
IPC: A47C27/10
Filed: 2022-03-22
Abstract: A mattress that includes a bottom mattress assembly and a top mattress assembly that may be assembled with each other. An internal overlap may be associated with the bottom mattress assembly and protrude beyond a top of a bottom core of the bottom mattress assembly to define a receptacle for a base portion of the top mattress assembly. A cover top and a cover bottom may be placed over the assembly and secured to each other at a location vertically below an upper extent of the internal overlap. The mattress may be modular and, thus, include a bottom mattress assembly selectable from a plurality of different configurations of bottom mattress assemblies and/or a top mattress assembly selectable from a plurality of different configurations of top mattress assemblies. Methods for assembling bottom mattress assemblies and top mattress assemblies with one another to provide a complete mattress are also disclosed.
Patent AU-2022252310-A1 (AU)
Title: Flame retardants for battery electrolytes
Inventor: VARNADO CHARLES
IPC: H01M10/0567
Filed: 2022-03-31
Abstract: This invention provides nonaqueous electrolyte solutions for lithium batteries. The nonaqueous electrolyte solutions comprise a liquid electrolyte medium; a lithium-containing salt; and at least one brominated flame retardant.
Patent AU-2022254867-A1 (AU)
Title: Lignin-based fracturing fluids and related methods
Inventor: SOMERVILLE DESMOND ALEXANDER
IPC: C08L97/00
Filed: 2022-04-05
Abstract: Fracturing or fracking fluids are provided for fracturing a subterranean reservoir for hydrocarbon recovery and related methods. In some embodiments, the fluid comprises lignin, in particular technical lignin, and at least one strain of bacteria capable of biosurfactant production and/or a biosurfactant produced by at least one such isolated strain of bacteria. Also provided is a fracturing method for recovering hydrocarbons from a subterranean formation.
Patent AU-2022256155-A1 (AU)
Title: Spatial management of audio
Inventor: WOOD STUART JOHN
IPC: G06F3/0481
Filed: 2022-10-20
Abstract: The present disclosure generally relates to user interfaces for managing spatial audio. Some 
exemplary techniques include user interfaces for transitioning between visual elements.  
Some exemplary techniques include user interfaces for previewing audio. Some exemplary 
techniques include user interfaces for discovering music. Some exemplary techniques 
include user interfaces for managing headphone transparency. Some exemplary techniques 
include user interfaces for manipulating multiple audio streams of an audio source.
Patent AU-2022256732-A1 (AU)
Title: Rna compositions comprising a buffer substance and methods for preparing, storing and using the same
Inventor: PANZNER STEFFEN
IPC: A61K9/51
Filed: 2022-04-11
Abstract: The present disclosure relates generally to the field of RNA compositions comprising a buffer substance, methods for preparing and storing such compositions, and the use of such compositions in therapy.
Patent AU-2022268460-A1 (AU)
Title: Methods for compensating colors based on luminance adjustment parameters and the related display devices
Inventor: WANG TSUN-I
IPC: G09G5/02
Filed: 2022-04-29
Abstract: Methods (300, 310, 320) for compensating colors based on luminance adjustment parameters and the related display devices. An electronic device (100) comprises: a display comprising an array of pixels (210, 220, 230，240) and a control circuit (130) electrically connected to the display. Pixels (210，220，230，240) in the array comprise a plurality of first sub-pixels defining a first color area (401，501) in a chromaticity plane (400，500，800，1000，1100，1200，1300), a plurality of second sub-pixels defining a second color area (402，502) in the chromaticity plane (400，500，800，1000，1100，1200，1300) and a plurality of third sub-pixels defining a third color area (403，503) in the chromaticity plane (400，500，800，1000，1100，1200，1300). The plurality of first sub-pixels is associated with a first primary color, the plurality of second sub-pixels is associated with a second primary color, and the plurality of third sub-pixels is associated with a third primary color. The control circuit (130) is configured to receive an input image signal and generate a control signal to the display for driving each pixel of the display to output light in a virtual color gamut (817，1019，1117，1217，1219，1317). The virtual color gamut (817，1019，1117，1217，1219，1317) of the display includes a first virtual color gamut including a first chromaticity coordinate point of the first primary color, a second virtual color gamut including a second chromaticity coordinate point of the second primary color, a third virtual color gamut including a third chromaticity coordinate point of the third primary color, and a fourth virtual color gamut. The fourth virtual color gamut is among the first, second and third color areas (401，501，402，502，403，503) on the chromaticity plane (400，500，800，1000，1100，1200，1300) and does not overlap any of the first, second or third color areas (401，501，402，502，403，503).
Patent AU-2022271476-A1 (AU)
Title: Nitrogen fixation using refactored nif clusters
Inventor: VOIGT CHRISTOPHER
IPC: C12N15/03
Filed: 2022-11-18
Abstract: The invention relates to methods for promoting fixed nitrogen from atmospheric nitrogen, and 
related products. Endophytic bacteria having an exogenous nif cluster promote fixed nitrogen 
for cereal plants. See Fig. 1.
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Patent AU-2022277689-A1 (AU)
Title: Methods and compositions for treating hematological malignancies
Inventor: TSANG KWONG
IPC: C07K16/28
Filed: 2022-05-19
Abstract: NEO-201 has been shown to specifically bind and kill hematological malignancy cells, e.g., acute myeloid leukemia (AML), and multiple myeloma. Diagnostic methods, therapeutic methods, and combination therapies using NEO-201 optionally in combination with another agent are described. In some embodiments, the hematological malignancy is characterized by cancer cells which express O-glycans.
Patent AU-2022290645-A1 (AU)
Title: Compounds useful in the treatment or prevention of a prmt5-mediated disorder
Inventor: LA THANGUE NICHOLAS
IPC: C07D401/14
Filed: 2022-06-10
Abstract: The present disclosure relates to compounds suitable for the inhibition of protein arginine methyl-transferase (PRMT), in particular PRMT5. These compounds may be for use as therapeutic agents, in particular, agents for use in the treatment and/or prevention of proliferative diseases, such as cancer.
Patent AU-2023202032-A1 (AU)
Title: Surgical trays, instruments and methods for implanting a hip replacement prosthesis
Inventor: TERMANINI ZAFER
IPC: A61F2/36
Filed: 2023-04-03
Abstract: A trial acetabular cup for a reverse hip prosthesis.
Patent AU-2023203714-A1 (AU)
Title: Model integration tool
Inventor: INDURTHIVENKATA RAJESH
IPC: G06F9/44
Filed: 2023-06-14
Abstract: Certain aspects involve building and debugging models for generating source code 
executed on data-processing platforms. One example involves receiving an electronic data
processing model, which generates an analytical output from input attributes weighted with 
respective modeling coefficients. A target data-processing platform is identified that requires 
bin ranges for the modeling coefficients and reason codes for the input attributes. Each bin 
range identifies a valid range of input attribute values for a modeling coefficient. The reason 
codes indicate impacts of different input attributes on the analytical output. A user interface is 
provided for specifying bin ranges and reason codes. Bin ranges and reason codes are identified 
from input received via the interface. Modeling code is generated that implements the 
electronic data-processing model with the bin ranges and the reason codes. The processor 
outputs source code, which is generated from the modeling code, in a programming language 
used by the target data-processing platform.
Patent AU-2023204661-A1 (AU)
Title: Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
Inventor: MAHR ANDREA
IPC: C07K14/47
Filed: 2023-07-13
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in 
immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of 
cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone 
or in combination with other tumor-associated peptides that can for example serve as active 
pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or 
to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major 
histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T
cell receptors, and other binding molecules.