baber/WOPTO huggingface dataset:
Patent CA-2537548-A1 (CA)
Inventor: ZHANG JINFANG
IPC: B60R1/12
Filed: 2006-02-21
Abstract: An improved multifunction mirror display system that combines the display of projected and reflected data in a single console by compressively coupling, without the use of adhesives, a reflective element (e.g. two-way mirror) with an emitting element (e.g. a liquid crystal display) within a housing. Compressive coupling of a reflective element with an emitting element is achieved by urging: (1) a reflective element against an emitting element; (2) an emitting element against a reflective element; or (3) both a reflective element and an emitting element against one another. Such an improved multifunction mirror display system can be used with overland, air, water and/or amphibious vehicles, buildings or non-occupied structures like sign posts, bridges and/or guard rails.
Patent CA-2538037-A1 (CA)
Title: Amino-substituted ethylamino .beta.2 adrenergic receptor agonists
Inventor: LINSELL MARTIN S
IPC: A61K31/40
Filed: 2004-09-21
Abstract: The invention provides novel .beta.2 adrenergic receptor agonist compounds.  The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with .beta.2 adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
Patent CA-2538748-A1 (CA)
Title: Cobalamin conjugates for anti-tumor therapy
Inventor: WEINSHENKER NED M
IPC: A61K47/48
Filed: 2004-09-10
Abstract: The present invention provides a cobalamin-drug conjugate suitable for the treatment of tumor related diseases. Cobalamin is indirectly covalently bound to an antitumor drug via a cleavable linker and one or more optional spacers.  Cobalanin is covalently bound to a first spacer or the cleavable linker via the 5'-OH of the cobalamin ribose ring. The drug is bound to a second spacer of the cleavable linker via an existing or added functional group on the drug.  After administration, the conjugate forms a complex with transcobalamin (any of its isoforms). The complex then binds to a receptor on a cell membrane and is taken up into the cell. Once in the cell, an intracellular enzyme cleaves the conjugate thereby releasing the drug. Depending upon the structure of the conjugate, a particular class or type of intracellular enzyme affects the cleavage. Due to the high demand for cobalamin in growing cells, tumor cells typically take up a higher percentage of the conjugate than do normal non-growing cells. The conjugate of the invention advantageously provides a reduced systemic toxicity and enhanced efficacy as compared to a corresponding free drug.
Patent CA-2538864-A1 (CA)
Title: Thalidomide analogs as tnf-alpha modulators
Inventor: ZHU XIAOXIANG
IPC: A61K31/45
Filed: 2004-09-17
Abstract: Thalidomide analogs that modulate tumor necrosis factor alpha (TNF-.alpha.) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs . Also disclosed are methods of treating a subject with the analogs.
Patent CA-2539295-A1 (CA)
Title: Improved sirna molecule and method of suppressing gene expression with the use of the same
Inventor: HOHJOH HIROHIKO
IPC: C12N15/113
Filed: 2004-08-18
Abstract: An improved double-stranded RNA molecule having been improved to thereby control the gene expression inhibitory effect of an siRNA. Namely, a double-stranded RNA molecule capable of inhibiting the expression of a target gene in a cell by RNAi wherein one or more nucleotides from the 3~- or 5~-end of the sense strand in the double-stranded part are converted into nucleotides which are not complementary to the antisense strand. In the sense strand of the double-stranded part of this double-stranded RNA molecule, moreover, the number of the nucleotides which are complementary to the antisense strand enables the hybridization of both strands in the above-described cell.
Patent CA-2540165-A1 (CA)
Title: Native immunoglobulin binding reagents and methods for making and using same
Inventor: LI GANGZHOU
IPC: C12N5/06
Filed: 2004-10-06
Abstract: Isolated native immunoglobulin binding reagents including antibodies are provided, along with articles of manufacture, compositions and kits that include the native immunoglobulin binding reagents. Labeled reagents and subtrates that comprise samples or the reagents are provided. Method of screening for, making and using the reagents are also provided.
Patent CA-2541501-A1 (CA)
Title: Immunogenic composition and method of developing a vaccine based on factor h binding sites
Inventor: KARP NELSON M
IPC: A61K39/12
Filed: 2004-10-25
Abstract: An immunogenic composition able to provide an immune response to Human Complement Factor H binding on one or more HIV glycoproteins is disclosed, which is characterized by at least one binding site epitope of the glycoproteins. Such immunogenic composition wherein the glycoprotein comprises gp120, gp4l, or both glycoproteins gp120 and gp4l is hereby disclosed. Sialic acid is removed to enhance immune recognition of the composition and to impair Factor H binding. A medication having an inhibitive action on autoimmune response by specific inhibition of the cleavage of C3b by Factor H into inactive cell fragments.
Patent CA-2542132-A1 (CA)
Inventor: TEBBE DENNIS L
IPC: H05K1/02
Filed: 2004-10-18
Abstract: Method for fabricating a textured dielectric substrate (400) for an RF  circuit.The method can include the step (104) of selecting a plurality of dielectric substrate materials, each having a distinct combination or set of electrical properties that is different from the combination of electrical properties of every other one of dielectric substrate materials. Selecting a textured substrate pattern (106) which is comprised of at least two types of distinct areas respectively having the distinct sets of electrical properties, with each distinct area dimensioned much smaller than a wavelength at a frequency of interest. Cutting the dielectric substrate materials (202, 204) into a size and shape consistent with the distinct areas of the selected pattern so as to form a plurality of dielectric pieces (206,208). Arranging the dielectric pieces on a base plate (302) in accordance with the selected pattern to form the textured dielectric substrate.
Patent CA-2543121-A1 (CA)
Title: Stabilized intervertebral disc barrier
Inventor: MOORE ROBERT KEVIN
IPC: A61F/
Filed: 2004-10-21
Abstract: Resilient surgical meshes that, in some aspects, can be compressed or otherwise configured, for minimally invasive delivery in the intervertebral discs are provided. According to one or more embodiments, the surgical mesh can be robust, fatigue resistant, stable and capable of withstanding the dynamic environment generic to intervertebral discs.
Patent CA-2543405-A1 (CA)
Inventor: CHADWICK FORREST RYAN
IPC: E04C5/06
Filed: 2003-12-05
Abstract: L'invention concerne une ouverture constituée par un ou plusieurs éléments d'un support, utilisés pour former des connexions malléables avec d'autres éléments de renfort. Ladite ouverture peut être constituée par le positionnement, le recourbement, l'entrecroisement ou l'embranchement d'un ou plusieurs de ces éléments. Les supports peuvent être disposés en parallèle ou selon des plans d'intersection et reliés par l'utilisation des ouvertures sur l'emplacement ou fabriqués hors site. Ils peuvent être assemblés dans des structures ou dans des panneaux modulaires, ou faits sur commande, avec lesquels ces structures peuvent être établies, et inclus dans des injections de ciment. L'isolation et d'autres systèmes mécaniques peuvent être incorporés à ces renforts et systèmes de panneaux avant imbrication dans des injections de ciment. Les renforts formant des ouvertures peuvent également être employés pour incorporer des structures de la technique antérieure avec des propriétés améliorées. Les systèmes interconnectés résultants d'ouvertures, de renforts, d'isolation et d'autres systèmes sont généralement sont inclus dans les injections de ciment afin de donner des structures avec des interconnexions de ductilité supérieure et un comportement composite amélioré.
Patent CA-2543444-A1 (CA)
Title: Method and apparatus for drying bulk material, especially bark, sawdust, pretreated sludge or a mixture of these, use of a wire, method and apparatus for cooling waste water produced in a production process of pulp or paper, pulp mill and paper mill
Inventor: KINNUNEN JUHANI
IPC: F26B3/06
Filed: 2004-10-29
Abstract: Method and apparatus are provided for drying bulk material, especially bark, sawdust, pretreated sludge or a mixture of these. Also provided are a method and apparatus for cooling waste water produced in a pulp or paper production process. Certain embodiments include a pulp mill, paper mill and a novel way of using a wire. Other embodiments provide for cooling in one and the same heat exchanger the waste water produced in a pulp or paper production process while simultaneously heating the gas that cools the waste water. Heated gas extracted from the heat exchanger is conducted through one or several drying conveyers and through the material to be dried that is conveyed on the drying conveyer so as to dry the material with the heated gas.
Patent CA-2544389-A1 (CA)
Title: An intervertebral prosthesis
Inventor: GILL STEVEN STREATFIELD
IPC: A61F2/00
Filed: 2004-10-26
Abstract: The application relates to an intervertebral prothesis (1). In particular, to an articulating intervertebral disc prothesis. In use, the intervertebral prosthesis is fixed to the end plates of vertebrae following the surgical excision of a degenerative or ruptured disc. The intervertebral prothesis has substantially flat bone engaging surfaces (7, 9) with a macro-textured surface.
Patent CA-2545567-A1 (CA)
Title: Rotary conveyor tine stripper with anti-wrap relief and/or notching
Inventor: ANSTEY HENRY DENNIS
IPC: A01D89/00
Filed: 2002-12-27
Abstract: An overshot rotary conveyor includes a plurality of sets of flat tines welded to a cylindrical shaft at respective locations spaced across the shaft, each tine including a curved leading edge. Located on the opposite sides of each flat tine and having forward ends received about the cylindrical shaft is a stripper including upper and lower halves. The lower half is shaped to provide a clearance zone below flat planar sides of the upper half, and to provide a stripper edge at each side which is at the front of the clearance zone and acts to push crop carried over by the adjacent tine into the clearance zone where the crop drops away. Located ahead of the stripper edges at the opposite sides of the lower stripper half in the vicinity of the cylindrical shaft is a notch having the purpose engaging, and deflecting away from the conveyor shaft, any crop that may be carried past the stripper edge by the conveyor tine.
Patent CA-2548884-A1 (CA)
Title: Concrete reclamation apparatus
Inventor: CONNARD LESLIE R III
IPC: B28C5/42
Filed: 2005-01-10
Abstract: An apparatus (10) which is useful in the separation of solids from a diluted, wet, concrete mixture has (a) a free-standing first container (16) with a drain port (24) and a top opening (26), (b) a strainer (18) disposed within the first container (16), (c) a drain port shut-off valve (56), (d) a second container (20) capable of providing a reservoir for recovered liquid, and (e) a transfer conduit (22) for allowing effluent from the drain port (24) of the first container (16) to gravitate into the second container (20).
Patent CA-2549867-A1 (CA)
Title: Methode de fabrication d'une plaque d'acier a haute resistance a la traction
Inventor: OI KENJI
IPC: C21D8/02
Filed: 2005-07-06
Abstract: Méthode de production de tôle en acier à haute résistance mécanique, consistant à: couler un acier dont la composition chimique, en % en masse, est la suivante: C:0,02 à 0,18 %, Si: 0,05 à 0,5 %, Mn: 0,5 à 2,0 %, Al: 0,005 à 0,1 %, N: 0,0005 à 0,008 %, P: 0,03 % ou moins, S: 0,03 % ou moins, le reste étant constitué de Fe et d'inévitables impuretés; laminer à chaud l'acier obtenu afin que la tôle présente une épaisseur prescrite sans la refroidir jusqu'à son point de transformation Ac3, ou à une valeur inférieure, ou après l'avoir réchauffée à son point de transformation Ac3 ou à une valeur supérieure; soumettre ensuite la tôle laminée à une trempe directe ou à un refroidissement accéléré à partir de son point de transformation Ac3 ou d'une valeur supérieure, pour la refroidir jusqu'à 400 °C ou à une valeur inférieure; puis porter la tôle refroidie à une température telle qu'une section centrale dans le sens de l'épaisseur de la tôle atteigne une température maximale d'au moins 520 °C, avec une vitesse moyenne d'élévation de température dans cette section de la tôle d'au moins 1 °C/s dans une plage de température allant de 460 °C à une température de revenu prescrite qui est son point de transformation Ac1 ou une valeur inférieure, au moyen d'un appareil de chauffage directement connecté à la même ligne de production que celle d'un laminoir et d'un appareil pour réaliser la trempe directe ou le refroidissement accéléré. Cette méthode permet de produire une tôle en acier à haute résistance mécanique, qui présente par rapport aux tôles conventionnelles un meilleur équilibre entre la résistance à la traction et la résistance avant PWHT et après PWHT, et possède une résistance à la traction supérieure ou égale à 570 MPa (N/mm2), grâce à l'utilisation, dans le traitement de revenu pour l'obtention d'une tôle en acier éteinte puis revenue, d'une valeur spécifique pour la vitesse d'élévation de température dans la section de la tôle d'acier centrale dans le sens de l'épaisseur.
Patent CA-2550248-A1 (CA)
Inventor: CATTEAU FREDERIC
IPC: B65D53/02
Filed: 2006-06-14
Abstract: The package has a container (100) with an opening (105) and a wall (101) defining an inner cavity (102) to receive a product. A rim (108) extends around the wall, and a cover (200) closes the opening. A liner (300) arranged between the container and cover to form a sealed closure is separated from the cavity by a conical portion (111) of the container/cover when the container is closed by the cover. The container has a notch extending in a direction transversal to the liner when the container is closed, where the notch allows the insertion of a tool between the liner and the container/cover.
Patent CA-2550539-A1 (CA)
Title: Multiphase fluid characterization
Inventor: SCOTT BENTLEY N
IPC: G01F1/74
Filed: 2006-07-11
Abstract: Methods for determining and validating a first phase fraction of a gravitationally-separated multiphase fluid by conducting physical and electrical property measurements on samples of the fluid. The water content of crude petroleum oil is determined after the oil and water have begun to separate into phase layers such as occurs during un-agitated holding of the crude petroleum oil. A series of measurements of electrical properties such as permittivity and physical properties such as density is collected. The density minima can be used to generate hindsight determinations of average properties, such as the dry oil phase density, which in turn can be used to increase the accuracy of the water percentage in the oil determined by the permittivity and density methods. Flow weighted averages of water percentages by each method can be used to determine and validate the water content of the crude petroleum oil.
Patent CA-2551706-A1 (CA)
Title: Herbal product comprising cinnamon and bitter melon
Inventor: SOLOMON DAVID
IPC: A61P3/06
Filed: 2006-06-27
Abstract: A new herbal product comprising cinnamon (Cinnamomi cassiae: Cinnamonum verum) and bitter melon (Momordica charantia). Each of these ingredients is known to demonstrate therapeutic effects but the combination of the two ingredients demonstrates significant synergism and improved therapeutic effects.
Patent CA-2556427-A1 (CA)
Title: Smooth draw-down for formation pressure testing
Inventor: KISCHKAT TOBIAS
IPC: E21B49/08
Filed: 2005-02-17
Abstract: A method and apparatus for of determining a formation parameter of interest.  The method includes placing a tool into communication with the formation to test the formation and drawing down a test volume at an increasing draw rate during a first draw period and decreasing the draw rate during a second draw period to create a smooth draw down cycle. The draw down can be step-wise or continuous. The formation parameter is determined using formation rate analyis and characteristics determined during the draw down cycle.
Patent CA-2561498-A1 (CA)
Inventor: HUNT JAMES B
IPC: A61F2/06
Filed: 2005-03-23
Abstract: A stent-graft assembly (10) is provided for a variety of medical treatment.  The stent-graft assembly includes a stent (12) disposed between an inner layer of graft material (18) and an outer layer of graft material (20). The graft layers are effectively secured to the stent by attaching the graft layers together through openings in the structure of the stent. Relative movement between the graft layers and the stent is made possible by providing unattached margins between the attached areas of the graft layers and the edges of the stent openings.
Patent CA-2564041-A1 (CA)
Title: Universal medication carrier
Inventor: DOWNEY HARVEY E
IPC: H04Q9/00
Filed: 2004-12-15
Abstract: A medication carrier for administering individual doses of therapeutic products to a patient, in a non-sequential fashion. The medication carrier comprises a receptacle which stores individually sealed, unit dose packages in random order, allowing each unit dose package to be easily accessed and released in response to automated or manual extraction. The medication carrier includes an array of stalls and retaining means for securing the sealed unit dose packages within the stalls until a scheduled dosing time. The unit dose packages are oriented such that identifiers imprinted thereon can be easily read without removing the packages from the carrier.
Patent CA-2564362-A1 (CA)
Title: Method for the packaging of editorial products in plastic film and the relative packaging
Inventor: TASSI LAMBERTO
IPC: B65B9/06
Filed: 2006-10-11
Abstract: A method for the packaging of editorial products (11) in plastic film comprising the phases of unwinding a plastic film (12) from a bobbin (13) and feeding it in a longitudinal direction (F), applying preprinted self-adhesive labels (16) to the film (12) transversally with respect to the longitudinal direction (F) and distanced between each other by a pre-established length greater than the length of the editorial products (11), positioning the editorial products (11) on the film (12) in the space between two subsequent labels (16), folding the plastic film (12) over the editorial products (11), welding the plastic film (12) longitudinally and transversally with a first transversal welding line (22) to form two containment areas (100a, 100b) of the label (16) and editorial product (11) respectively, and also with a second transversal welding line (23) forming a head of a finished packaging (100,100') separated by means of the second transversal welding.
Patent CA-2564379-A1 (CA)
Title: Aerosol formulation for inhalation of beta agonists
Inventor: AVEN MICHAEL
IPC: A61K31/536
Filed: 2005-05-10
Abstract: The invention relates to a propellant-free aerosol formulation for inhalatio n, which comprises one or more compounds of general formula (1), wherein the groups R1, R2, R3 and X- are defined as in the claims and in the description .
Patent CA-2566395-A1 (CA)
Inventor: ROGAN PETER K
IPC: G01N33/48
Filed: 2005-03-28
Abstract: The present invention provides a novel method for selecting genomic hybridization probes. The method generally includes the step of selecting a genomic interval of interest, identifying at least one potential hybridization probe that has known coordinates within the interval of interest, applying a numerical method to sample the identified probe(s) based on its genome coordinates, and selecting a probe based on the result of the numerical method.
Patent CA-2566489-A1 (CA)
Inventor: LAKANIEMI ARI
IPC: G10L19/14
Filed: 2005-04-15
Abstract: The invention relates to a method for supporting an encoding of an audio signal, wherein a first coder mode and a second coder mode are available for encoding a respective section of an audio signal. The second coder mode enables a coding of a respective section based on a first coding model, which requires for an encoding of a respective section only information from the section itself, and based on a second coding model, which requires for an encoding of a respective section in addition an overlap signal with information from a preceding section. After a switch from the first coder mode to the second coder mode, always the first coding model is used for encoding a first section of the audio signal. This section can then be employed to generate an artificial overlap signal for a subsequent section, which is possibly to be encoded with the second coding model.
Patent CA-2568205-A1 (CA)
Title: Turbocombustion engine
Inventor: YADEGAR JERRY IRAJ
IPC: F02B73/00
Filed: 2005-05-26
Abstract: A turbocombustion engine for conversion of combustible fuel to rotating energy includes a cylinder, piston, connecting rod and crankshaft system for suction and compression and a rotor for expansion and exhaust. Combustible fuel is compressed within a combustion chamber separate from the cylinder and the combustion force applied directly to the rim of the rotor as in turbines with much larger capacity than the cylinder, converting the entire combustion force at maximum torque to rotating energy. The combustion chamber also includes a variable compression ratio system that constantly adjusts the compression ratio within the combustion chamber for optimum performance of the engine under all variables.
Patent CA-2573764-A1 (CA)
Inventor: SHIH NENG-YANG
IPC: A61P43/00
Filed: 2005-07-13
Abstract: This invention relates to compounds of Formula (1) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF- or combinations thereof.
Patent CA-2576351-A1 (CA)
Title: Tire management system
Inventor: FUKUMORI HAJIME
IPC: B60C23/04
Filed: 2007-01-26
Abstract: A receiving module selects frequencies to be used for data request signals from all channels if there is no channel prohibited from being used, and if there are channels prohibited from being used, the receiving module selects frequencies to be used for data request signals from channels other than the channels prohibited from being used. In the case failed in acceptance of measured data from a sensor module, the receiving module sets communication channels failed in acceptance of measured data predetermined times to prohibited channels from being used. In this manner, when the receiving module transmits the data request signals to the sensor module, frequencies of channels having jamming radio waves and the like could not be selected by the receiving module, thereby enabling the receiving module to select the frequencies of high probability in communication reception.