baber/WOPTO huggingface dataset:
Patent JP-4060372-B2 (JP)
IPC: C12Q1/6897
Filed: 1997-12-10
Granted: 2008-03-12
Abstract: A two-hybrid system that can detect homo- and heterodimeric protein interactions in E. coli and other cells. This system is useful for the same applications as a yeast two-hybrid system; i.e. interaction cloning, mapping protein interaction domains, analyzing protein interactions, detecting protein interactions and detecting modulators thereof. The invention concerns a prokaryotic host cell comprising: (a) a fusion protein having (i) a first DNA-binding domain and (ii) a first interacting domain; (b) a fusion protein having (i) a second DNA-binding domain and (ii) a second interacting domain capable of binding to the first interacting domain; and (c) a nucleic acid molecule having a reporter gene operatively linked to (i) a promoter, (ii) a first operator site capable of binding to the first DNA-binding domain, located upstream of the promoter, and (iii) a second operator site capable of binding the second DNA-binding domain, located downstream of the promoter of the reporter gene; wherein binding of the first interacting domain to the second interacting domain is signaled by altered expression of the reporter gene.
Patent JP-4317590-B2 (JP)
IPC: G08B29/12
Filed: 1996-02-01
Granted: 2009-08-19
Abstract: PCT No. PCT/DE96/00146 Sec. 371 Date Sep. 22, 1997 Sec. 102(e) Date Sep. 22, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/29609 PCT Pub. Date Sep. 26, 1996In the case of a multichannel monitoring device for monitoring system operating states, a test input (45a, 45b) is provided per channel (2, 3) on an evaluation and monitoring circuit for the purpose of testing the supply leads (7a, 7b) to the signalling units (1a, 1b) for freedom from damage. Either no filters or filters (47a, 47b) with a short settling time are provided in the supply lead to this test input (45a, 45b). As a result, testing requires only a very short time, so that the evaluation of the signalling units (1a, 1b) is interrupted only for a very short time. The time is so short that no dangerous system states can occur.
Patent JP-2912022-B2 (JP)
IPC: G11C7/00
Filed: 1996-03-12
Granted: 1999-06-28
Abstract: A circuit and method provide isolated modulation of SRAM bitline voltage levels for improved voltage bump retention testing of the SRAM cells. A first FET is connected to Vcc, bitline load gates of the SRAM cell, and test mode operation control logic. A second FET is connected to the bitline load gates, the test mode logic, and an external pin of the SRAM device. During test mode operation, the first FET disables Vcc to the bitlines, and the second FET enables the internal bitline voltage levels to be modulated by a voltage supply received through the external pin of the device. Modulation of the bitline voltage levels is isolated from normal operating voltage levels of peripheral circuitry such as the wordlines. An alternate embodiment provides a CMOS transmission gate in place of the second FET.
Patent JP-3937451-B2 (JP)
IPC: C09D7/00
Filed: 1996-04-23
Granted: 2007-06-27
Abstract: PCT No. PCT/EP96/01682 Sec. 371 Date Apr. 6, 1998 Sec. 102(e) Date Apr. 6, 1998 PCT Filed Apr. 23, 1996 PCT Pub. No. WO96/34062 PCT Pub. Date Oct. 31, 1996The invention relates to an aggregated silica gel which has been produced from silica gel particles having a particle size of 1 to 20 mu , a surface of 200 to 1000 m2/g and a specific pore volume of 0.4 to 2.5 ml/g and a binding agent selected from synthetic or natural phyllosilicate, pyrogenic silicon dioxide and organic polymers soluble in water or dispersible in water. Aggregation takes place by spray-drying a suspension having 1 to 25% solids. The product is suitable as a matting agent for coatings, as an antiblocking agent for polymer films and as a beer clarifying agent.
Patent JP-3318593-B2 (JP)
IPC: C09J7/20
Filed: 1997-03-28
Granted: 2002-08-26
Abstract: An impact absorptive material comprising a base material and a moment activator which can increase the amount of dipole moment in said base material.
Patent AU-2001230334-B2 (AU)
Title: Speed trap detection and warning system
Inventor: GROVES MARK DAVID
IPC: G08G1/0967
Filed: 2001-01-25
Granted: 2006-12-07
Abstract: A speed trap detection and warning system for a vehicle (9) comprises a GPS or mobile telephone signal receiver and processor which calculates the location of the vehicle (9), the speed thereof and the direction of travel thereof, a memory storing data defining the location of a number of speed traps (5, 6) and alerts the driver if the vehicle is within a predetermined distance of a speed trap and the vehicle's speed is greater than the road speed limit. Also disclosed is a system for calculating the location and speed of a vehicle (9), comparing the calculated data with stored data defining the locations of roads and the speed limits therefor, and alerting the driver if the vehicle's speed exceeds the speed limit for the road on which it is travelling. A further system is disclosed for displaying to the driver the speed limit for the road on which the vehicle is travelling.
Patent AU-2001231674-B2 (AU)
Title: Pattern
Inventor: STAUB RENE
IPC: B42D15/10
Filed: 2001-01-12
Granted: 2005-10-20
Abstract: A surface pattern (18) is in the form of a visually visible mosaic comprising a number of surface portions (8; 9; 15; 16; 17) and is embedded in a laminate (1) comprising at least a transparent cover layer (2) and a protective layer (5). The surface portions (8; 9; 15; 16; 17) are transparent, scatter or reflect incident light (10) or diffract the incident light (10) at microscopic relief structures (4). The surface portions (8; 9; 15; 16; 17) are at least partially covered with a reflection layer (3). At least one of the surface portions occupied by a microscopic relief structure (4), an area (16), is a ZOM-structure (4') with a predeterminedly slowly varying profile height h and a spatial frequency f, wherein the product of a predetermined limit wavelength lambdaG of the visible spectrum and the spatial frequency f is greater than or equal to one.
Patent AU-2001270101-B2 (AU)
Title: Conserved diaphanous-related formin autoregulatory domain (DAD)
Inventor: ALBERTS ARTHUR S
IPC: A61K38/00
Filed: 2001-06-22
Granted: 2006-05-25
Abstract: The Diaphanous-related formins (DRFs) constitute a subclass of FH proteins known for their ability to bind activated Rho subfamily of small GTP-binding proteins which link FH proteins to cellular signalling pathways. The present inventor has identified a new homology domain unique to the DRFs that termed the DRF-autoregulatory domain (DAD) in the extreme Cterminus. DAD is involved in intramolecular binding with the GTPase binding domain (GBD) of the DRFs. Disclosed herein are compositions and methods that can disrupt this binding, and cause changes in cells including actin polymerization and/or stabilization of actin fibers resulting in growth inhibition or cell death by apoptosis. A preferred composition is peptide or polypeptide of no more than about 130 amino acids comprising the DAD peptide having the amino acid sequence [GA]-[VA]-M-D-x-L-L-E-x-L-[KRQ]-x-[GA]-[SGA]-[AP] (wherein amino acids within a set of brackets are interchangeable and x means any amino acid). Fusion proteins comprising DAD are also disclosed as are nucleic acids and expression vectors encoding these peptides and proteins.
Patent AU-2001274268-B2 (AU)
Title: A rotary ski slope
Inventor: MCLAREN DAVID
IPC: E01C13/12
Filed: 2001-06-19
Granted: 2006-10-26
Abstract: A rotary ski slope comprising an inclined disc which is rotatable about an axis and has a diameter of at least 100 meters. The disc may be divided into a number of concentric rings ( 1 ) which are rotatable at different speeds. Means are preferably provided to circulate coolant across the entire under surface of the disc to prevent the snow from melting. The entire surface of the disc is preferably available for skiing with snow conditioning and grooming apparatus ( 49, 52 ) being mounted away from the surface, or selectively retractable from the surface. The upper surface of the disc may be non-planar to set up "wave" allowing a variety of skiing conditions to be provided.
Patent AU-2001291716-B2 (AU)
Title: Vaccination against host cell-associated herpesviruses
Inventor: FEHLER FRANK
IPC: A61K39/245
Filed: 2001-08-01
Granted: 2007-06-07
Abstract: The invention relates to the field of so-called host cell-associated herpesviruses such as Marek's disease like virus (MDV) of poultry and of Varicella Zoster Virus (VZV) of man and to vaccination against disease caused by these viruses. The invention provides a vaccine directed against an infection caused by an herpesvirus that is essentially host cell associated comprising a recombinant viral genome derived from said herpesvirus, said genome allowing recombination essentially free of said host cell.
Patent AU-2002217459-B2 (AU)
Title: Holder of contact lens for vitreous body operation, and holding part and connection part of contact lens for vitreous body operation
Inventor: TANO YASUO
IPC: A61F9/00
Filed: 2001-12-19
Granted: 2007-08-09
Abstract: In surgery of the vitreous body in an eyeball of a human body, a burden on and time of a surgeon is suppressed from being spent, a burden on the eyeball of a patient is greatly reduced, and further, the possibility of a complication after the surgery is also lessened. A holding apparatus 1, which is characterized in that it comprises eyelid opener portions 10a and 10b for pulling and opening upper and lower eyelids, a lens ring 30 for holding a surgical contact lens on the eyeball, and connecting portions 40a and 40b for connecting the eyelid opener portions 10a and 10b with the lens ring 30 of the surgical contact lens so that the surgical contact lens is held on the eyeball, is set on the eyeball of the patient, which makes it unnecessary to stitch of the lens ring 30 on the eyeball. <IMAGE>
Patent AU-2002235867-B2 (AU)
Title: Method for recycling pulp rejects
Inventor: MUENCHOW DIETER
IPC: D21H19/00
Filed: 2002-01-24
Granted: 2006-12-14
Abstract: The present invention relates to a process for recycling cleaner rejects from the preparation of paper, paperboard and cardboard and to their use for the preparation of paper in the paper stock or as a coating slurry for the paper industry.
Patent AU-2002332182-B2 (AU)
Title: Process for producing poly(ethylene-aromatic dicarboxylate ester) resin and resin product
Inventor: TSUKAMOTO RYOJI
IPC: C08G63/85
Filed: 2002-09-18
Granted: 2007-09-13
Abstract: Process for producing poly(ethylene-aromatic dicarboxylate ester) resin comprises subjecting a diester of an aromatic dicarboxylic acid and an ethylene glycol to condensation-polymerization in the presence of a catalyst comprising a mixture of titanium- and phosphorus- compounds. Process for producing poly(ethylene-aromatic dicarboxylate ester) resin comprises subjecting a diester of an aromatic dicarboxylic acid and an ethylene glycol to condensation-polymerization in the presence of a catalyst. The catalyst comprises a mixture of titanium- and phosphorus- compounds, and is obtained by regulating the concentration of P and Ti atoms of a reaction product of, or an unreacted mixture of, a P-containing compound component and a Ti-containing compound component. The titanium compound component contains one or more Ti-alkoxide compounds and a reaction product between a Ti-alkoxide and an aromatic polycarboxylic acid or its anhydride. The P-containing compound component contains at least one compound represented by general formula (1), (2) and (3). [Image] R 1>, R 2>, R 3>1-4C alkyl group; X : -CH 2- or group represented by (1a); R 4>2-18C alkyl or 6-20C aryl group; n : 1 or 2; p : 0 or 1 (when n = 1), and 0 (when n = 2); m, ma, mb : 0 or 1. The amount of the constituents of the catalyst satisfy the following relationships. 2 = M r i= 15 (a) 1 = (M p/ M r i) = 15 (b) 10 = (M r i+ M p) = 100 (c) M r iratio of the amount of Ti (mmol) contained in the catalyst to the total amount of mol of ethylene-aromatic dicarboxylate ester contained in the poly(ethylene-aromatic dicarboxylate ester); and M p : ratio of the amount of P (mmol) contained in the catalyst to the total amount of mol of ethylene-aromatic dicarboxylate ester contained in the poly(ethylene-aromatic dicarboxylate ester).
Patent AU-2002363589-B2 (AU)
Title: Use of a mixture of sodium hyaluronate and chondroitin sulfate for a treatment of osteoarthritis
Inventor: HERMIDA OCHOA ELIAS HUMBERTO
IPC: A61K31/715
Filed: 2002-11-13
Granted: 2007-11-29
Abstract: This invention is related to the use of a composition formed by sodium hyaluronate, sodium chondroitin sulfate and botulinum toxin type A for the treatment of dermal lines, and to the use of such composition in the manufacture of a product for such treatment.
Patent AU-2003233662-B2 (AU)
Title: Fas peptide mimetics and uses thereof
Inventor: HASEGAWA AKIHIRO
IPC: C07K14/525
Filed: 2003-05-23
Granted: 2010-04-01
Abstract: Exocyclic peptide mimetics that disable Fas were developed. A three dimensional model of the Fas receptor-ligand complex was constructed and structurally predicted regions of the receptor that were relevant to binding ligand were used to create constrained peptide mimetics. Exocyclic anti-Fas peptide mimetics were identified that block Fas receptor-ligand interactions, and modulate Fas biological activity both in vitro and in vivo. The mimetics are useful, e.g., for treating Fas-related pathologies.
Patent AU-2003236326-B2 (AU)
Title: A Therapeutic Agent for Impaired Gastric Accommodation
Inventor: HIGASHINO RAITA
IPC: A61P1/00
Filed: 2003-04-08
Granted: 2008-02-28
Abstract: A therapeutic agent for impaired gastric accommodation which contains as an active ingredient a compound represented by the general formula (1):   
(wherein R 1  represents a hydrogen atom, a hydroxyl group or a halogen atom; A represents a furyl group, a thienyl group, a thiazolyl group or an oxazolyl group; R 2  and R 3  each represents an alkyl group with 1 to 5 carbon atoms; and n represents an integer of 2 to 4), or an acid addition salt thereof.
Patent AU-2004208734-B2 (AU)
Title: A mouthguard
Inventor: BURNS PETER
IPC: A63B71/08
Filed: 2004-09-07
Granted: 2007-12-13
Abstract: A mouthguard ( 10 ) of "C" shaped configuration having a forward portion ( 11 ) from which there rearwardly diverges a pair of arms ( 12 ). The mouthguard ( 10 ) in transverse cross section is of a "U" shaped configuration. In one embodiment each arm ( 12 ) is provided with a ridge ( 22 ) which acts as a shield, while the forward portion ( 11 ) is thickened so as to provide a labial shield ( 23 ).
Patent AU-2004281152-B2 (AU)
Title: Cystatin C as an antagonist of tgf-b and methods related thereto
Inventor: SCHIEMANN WILLIAM P
IPC: A01N37/18
Filed: 2004-10-15
Granted: 2012-01-19
Abstract: Disclosed are Cystatin C (CysC) homologues, including CystC homologues that act as antagonists or inhibitors of transforming growth factor-β (TGF-β). Also disclosed are methods to identify CystC homologues that are antagonists or inhibitors of TGF-β and compositions and therapeutic methods using CystC and homologues thereof to regulate the activity of TGF-β, and TGF--βmediated tumor malignancy and invasion and other TGF--βmediated fibrotic or proliferative conditions and diseases.
Patent AU-2004296879-B2 (AU)
Title: Substituted piperazines
Inventor: PENNELL ANDREW M K
IPC: C07D405/04
Filed: 2004-12-08
Granted: 2011-11-17
Abstract: Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
Patent AU-2004314756-B2 (AU)
Title: Spring element for rail vehicles
Inventor: VOLKER GEDENK
IPC: F16F1/374
Filed: 2004-12-08
Granted: 2011-06-16
Abstract: The spring for use in rail vehicle suspensions comprises a rubber sphere (4) mounted between top (6) and bottom (8) plates. The sphere has longitudinal (14a - 14c) and transverse (16a - 16c) ribs over its surface which enclose polygonal fields (18a - 18c) between them.
Patent AU-2005213767-B2 (AU)
Title: Method and device for quantizing a data signal
Inventor: WABNIK STEFAN
IPC: G10L19/26
Filed: 2005-02-10
Granted: 2008-04-10
Abstract: Quantizing an information signal of a sequence of information values includes frequency-selective filtering the sequence of information values to obtain a sequence of filtered information values and quantizing the filtered information values to obtain a sequence of quantized information values by means of a quantizing step function which maps the filtered information values to the quantized information values and the course of which is steeper below a threshold information value than above the threshold information value.
Patent AU-2005245031-B2 (AU)
Title: Methods of treating cancer using IL-21 and monoclonal antibody therapy
Inventor: FOSTER DONALD C
IPC: C07K16/28
Filed: 2005-05-20
Granted: 2011-08-18
Abstract: Methods for treating cancer by co-administering a therapeutic monoclonal antibody with IL-21 are described. Exemplary monoclonal antibodies that can be used are rituximab, trastuzumab and anti-CTLA-4 antibodies. The enhanced antitumor of the combination therapy is particularly useful for patient populations that are recalcitrant to monoclonal therapy, relapse after treatment with monoclonal antibodies or where the enhanced IL-21 antitumor effect reduces toxicities associated with treatment using the monoclonal antibodies.
Patent AU-2005258161-B2 (AU)
Title: Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
Inventor: LOPEZ JUAN F
IPC: C12Q1/68
Filed: 2005-06-21
Granted: 2011-05-26
Abstract: The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.
Patent AU-2005274704-B2 (AU)
Title: Magnetic particle capture of whole intact organisms from clinical samples
Inventor: MC MILLAN RAY A
IPC: G01N33/543
Filed: 2005-07-19
Granted: 2011-09-15
Abstract: A method includes providing a sample (10) containing at least one whole, intact particle or organism (20) in a container (15); creating a mixture (25) comprising the sample (10), at least one magnetically-responsive particle (30), and a remainder; and providing the mixture (25) with a pH of less than about 7.0. By providing the mixture (25) with a pH of less than about 7.0, alteration of the surface charge properties of at least the one magnetic particle (30) occurs, thereby causing the at least one whole, intact particle or organism (20) to become non-specifically bound to the at least one magnetically-responsive particle (30) to form a complex.
Patent AU-2005281942-B2 (AU)
Title: Connecting module to be used in telecommunication and data technology
Inventor: NIJHUIS ANTONY
IPC: H04Q1/14
Filed: 2005-08-30
Granted: 2010-02-25
Abstract: A connection module that mounts to a frame includes a housing and electrical contacts positioned on different ends of the housing. A first fixing member defines a channel sized to receive at least a portion of a frame. A second fixing member is moveable relative to the first fixing member to extend at least partially across the channel of the first fixing member.
Patent AU-2006201512-B2 (AU)
Title: Replaceable nozzle for producing a frothed liquid
Inventor: ALFRED YOAKIM
IPC: A47J31/41
Filed: 2006-04-11
Granted: 2011-12-08
Abstract: Abstract: A nozzle (1) adaptable to the steam outlet of a coffee machine is designed to froth a 5 liquid such as e.g. milk. Said nozzle comprises in the direction of the steam flow path: - a steam inlet opening (3), - a restriction (4) with limited cross-section adapted to accelerate the velocity of the steam flow, and - at least one cavity (5) having a cross-section larger than the restriction (4) and from 10 which the frothed liquid can be drained. The nozzle further comprises an outer casing (30) comprising a smoothening reservoir (31) and a jet breaking surface (34) facing the opening (6) and at least one outlet opening (32) radially offset relatively to the opening (6) of the portion of the enlarged mixing cavity. The outer casing (30) is arranged at least partially around the tubular portion of mixing cavity (5). Figure 4 7z 5 31 - L2 6 35 L -32
Patent AU-2006225808-B2 (AU)
Title: Solar light pumped laser and cooling system of solar light pumped laser
Inventor: UCHIDA SHIGEAKI
IPC: H01S3/0915
Filed: 2006-03-10
Granted: 2011-09-08
Abstract: [PROBLEMS] To provide a solar light pumped laser and its cooling system. [MEANS FOR SOLVING PROBLEMS] The solar light pumped laser (10) performing laser oscillation by pumping a laser medium with solar light, comprises the laser medium (12), a containing device (14) that supports the laser medium (12) internally and is provided with a condensing optical element (22) for irradiating solar light condensed along the laser medium (12) while holding cooling liquid in a space between the laser medium (12) and the containing device (14), and a pair of optical reflection elements (16,18) arranged contiguously to the opposite ends of the laser medium (12). End of the containing device (14) has Brewster’s angle. The cooling liquid contains water that functions as an optical medium to form a water lens and, at the same time, cleans the condensing optical element (22).
Patent AU-2006241992-B2 (AU)
Title: Drug solution container package and method for manufacturing the same
Inventor: HITOSHI MORI
IPC: A61J1/10
Filed: 2006-04-19
Granted: 2011-11-03
Abstract: An object of the invention is to provide a housing body for a medical liquid container which can highly suppress degradation of a medical liquid, growth of bacteria or the like associated with oxygen permeation while maintaining properties required for a plastic medical liquid container such as heat resistance, impact resistance, flexibility, transparency and elution resistance to a plastic molding material and a process for producing the same. In order to achieve the object, a medical liquid is packed and sealed in a plastic medical liquid container whose oxygen permeability (25°C, 60% RH) within 12 hours after treated by steam sterilization or hot water sterilization is 200 cm/m⋅24h⋅atm or higher and oxygen permeability (25°C, 60% RH) in a steady state is 100 cm/m⋅24h⋅atm or lower, and the plastic medical liquid container is treated by steam sterilization or hot water sterilization, and then housed and sealed in an outer bag having an oxygen barrier property together with a deoxygenating agent.
Patent AU-2006284981-B2 (AU)
Title: A method for gravel or frac packing in a wellbore and for monitoring the packing process
Inventor: CORONADO MARTIN P
IPC: E21B43/267
Filed: 2006-08-30
Granted: 2011-09-08
Abstract: A method for gravel packing or frac packing in a borehole includes running a workstring to a target location, running an optic fiber to the location with the workstring and monitoring the target location with the optic fiber. A method for monitoring at least one parameter at a plurality of discrete locations at a gravel packing or frac packing location in a borehole including running a workstring to the gravel packing or frac packing location running an optic fiber to the gravel packing or frac packing location along with the workstring and monitoring the gravel packing or frac packing location at a plurality of discrete points along the gravel packing or frac packing location.