baber/WOPTO huggingface dataset:
Patent CA-2504041-A1 (CA)
Title: Stabilization of biomolecules in samples
Inventor: KREVOLIN MARK D
IPC: C12Q1/68
Filed: 2005-04-06
Abstract: This invention generally relates to stabilized non-blood-based samples in which microbial biomolecules in non-blood-based samples are stable at high temperatures. The stabilized non-blood-based samples include effective amounts of stabilization components to stabilize the microbial biomolecules in the samples.  Stabilization components are typically effective at low levels in these stabilized non-blood-based samples. This provides the advantage of minimizing reagent expenses related to the stabilized non-blood-based samples of the invention. The invention also provides methods of stabilizing microbial biomolecules in non-blood-based samples and related kits.
Patent CA-2505312-A1 (CA)
Title: Guidage de pression et de temperature dans un procede de revetement dans le moule
Inventor: STRAUS ELLIOTT J
IPC: B29C45/16
Filed: 2003-11-06
Abstract: L'invention concerne un procédé de revêtement dans le moule, dans lequel le moment où le substrat de revêtement est injecté sur une surface d'un substrat moulé est déterminé par la température et/ou par la pression du moule intérieur. La régulation du point auquel le revêtement dans le moule est injecté, en fonction de la température et/ou de la pression du moule intérieur, permet à l'opérateur de s'assurer que le revêtement dans le moule est injecté lorsque la surface du substrat moulé se trouve dans une condition idéale pour une adhésion de revêtement dans le moule.
Patent CA-2513281-A1 (CA)
Title: Pharmaceutical combination for the prevention or treatment of cardiovascular, cardiopulmonary, pulmonary or renal diseases
Inventor: MARK MICHAEL
IPC: A61K31/401
Filed: 2004-01-14
Abstract: The invention relates to a method for the prophylaxis or treatment of cardiovascular, cardiopulmonary, pulmonary or renal diseases, achieved by the improvement of endothelial function and the protection of organs, tissues and vessels when indications require a blood pressure check and a lipid level check, especially in patients that have been diagnosed with type 2 diabetes mellitus or if prediabetes is suspected. Said method is also used for preventing diabetes and prediabetes and for the treatment of metabolic syndrome and insulin resistance in patients with normal blood pressure. Said method involves the common administration of effective quantities of telmisartan or a polymorph or salt thereof and simvastatin. The invention also relates to suitable pharmaceutical compositions, containing telmisartan or a polymorph or salt thereof and simvastatin, as a combined preparation for simultaneous, separate or sequential use in the prophylaxis or treatment of said diseases.
Patent CA-2514171-A1 (CA)
Title: Method of immobilising hydrocarbons inside submerged containers or of transporting said hydrocarbon to the surface, using the properties of supercritical fluids at a great depth
Inventor: PRIETO BARRANCO JOSE
IPC: B01J3/00
Filed: 2004-01-26
Abstract: The invention relates to a method of immobilising a hydrocarbon contained inside a container submerged in the sea floor or of transporting said hydrocarbon to the surface using the pressure gradient between the pressure in the sea floor and the pressure generated at the lower opening of a hydrostatic column in which the fluid used as the supercritical fluid is gasified when same moves to non-extreme pressure conditions.
Patent CA-2514553-A1 (CA)
Inventor: WADDELL KEVIN K
IPC: E21B43/10
Filed: 2004-01-26
Abstract: A lubrication system for lubricating an interface (22) between one or more expansion surfaces (12 a) of an expansion device (12) and one or more interior surfaces (16a) of a tubular member (16) during a radial expansion of the tubular member (16) using the expansion device (12).
Patent CA-2518935-A1 (CA)
Inventor: KIM JOONHO
IPC: B65B1/30
Filed: 2003-05-07
Abstract: La présente invention a trait à un plateau d'ensembles de cassettes de comprimés pour appareil de distribution et d'emballage automatique de comprimés comportant des supports de cassettes de comprimés disposés d'un côté d'armoires et montés avec des cassettes de comprimés contenant des comprimés correspondants. Le plateau d'ensembles de cassettes de comprimés comporte : une paire de plateaux d'ensembles de cassettes de comprimés disposés de l'autre côté des armoires pour constituer des sections d'évacuation de comprimés selon des lignes verticales d'ensembles de cassettes de comprimés pour guider les comprimés évacués depuis la cassette de comprimés dans une unité d'emballage, dans lequel le premier plateau d'ensembles de cassettes de comprimés est relié à demeure à des armoires respectives, et comporte des moyens d'attache pour l'accouplement du premier plateau d'alignement de cassettes de comprimés au deuxième plateau d'ensembles de cassettes de comprimés, le deuxième plateau d'ensembles de cassettes de comprimés est divisé longitudinalement en un certain nombre de plateaux secondaires à espacement prédéterminé, et des moyens d'attache sont prévus respectivement dans les plateaux secondaires d'ensembles de cassettes de comprimés, et reliés aux moyens d'attache prévus dans le premier plateau d'ensembles de cassettes de comprimés, grâce à quoi les plateaux secondaires d'ensembles de cassettes de comprimés sont détachés séparément lors de nettoyage ou d'entretien pour ouvrir l'intérieur du canal d'évacuation de comprimés.
Patent CA-2519027-A1 (CA)
Inventor: SLEEP DARRELL
IPC: C07K14/76
Filed: 2004-03-15
Abstract: An agent having a greater half-life than naturally produced albumin in a patient with NS, the agent comprising an albumin-like first polypeptide bound to a second polypeptide, wherein the second polypeptide, when bound to the albumin-like first polypeptide is therapeutically inert and wherein if the agent consists of two albumin molecules, then they are covalently joined to one another other than solely by means of one or more cysteine-cysteine disulphide bridges.
Patent CA-2520386-A1 (CA)
Inventor: MUNSON ROBERT S JR
IPC: C07K14/285
Filed: 2004-03-24
Abstract: The invention relates to a mutation within the sap operon of an avirulent clone of a nontypeable strain of Haemophilus influenzae (NTHi). The invention also relates to the NTHi sap operon genes and the polypeptides encoded by these polynucleotide sequences. The invention also relates to a novel 110kDaNTHi outer membrane protein and the polynucleotide that encodes this outer membrane protein. Methods of screening for NTHi infecting, and treating and preventing NTHi related disorders are also contemplated.
Patent CA-2520460-A1 (CA)
Title: Use of fgf- 18 protein, target proteins and their respective encoding nucleotide sequences to induce cartilage formation
Inventor: WHITSETT JEFFREY ALLEN
IPC: C12N5/077
Filed: 2004-03-26
Abstract: The use of fibroblast growth factor (FGF)-18 protein, certain of its downstream target genes and respective expressed proteins, in particular sonic hedgehog (Shh), Shh protein, .beta.-catenin, .beta.-catenin protein, and the Wnt family of proteins that stimulate .beta.-catenin, and the respective nucleotide sequences encoding this protein, particularly for inducing cartilage formation, particularly for the purpose of generating, repairing, reconstructing, or de novo formation of, cartilaginous tissue. Therapies for which FGF-18 and the target proteins are useful include repair and reconstruction of various tissues in conducting airways such as the trachea, bronchi, lung and larynx caused by, for example, tracheal-bronchial abnormalities, tracheal-laryngo or bronchial malaria. Other therapies for which FGF-18 and the target proteins would be useful include other cartilaginous tissues, such as those of joint and skeletal tissue caused by, for example, arthritis and meniscus abnormalities in joints.
Patent CA-2523812-A1 (CA)
Title: Compliant venous graft
Inventor: DOUK NAREAK
IPC: A61F2/90
Filed: 2004-04-28
Abstract: A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by the tubular support, the venous graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.
Patent CA-2527166-A1 (CA)
Title: Apparatus for playing a flying disc throwing game
Inventor: MERCIECA TONY
IPC: A63F9/02
Filed: 2005-11-17
Abstract: The apparatus has a target which consists of two or more cylinders which rest on a support. The object of the game is to strike the cylinders with the flying disc from a distance so that they fall off the support. The cylinders are of unequal length such that striking the shorter disc by the flying disc when it is thrown a given distance requires greater skill than striking the longer cylinder when the disc is thrown the same distance. The support may be inflatable so that the game can be played in water.
Patent CA-2534831-A1 (CA)
Title: .delta.15-d-homosteroids having an androgenic effect
Inventor: WYRWA RALF
IPC: A61K31/12
Filed: 2004-08-19
Abstract: The invention relates to .DELTA.15-D-homosteroids of general formula (I), methods for the production thereof, and pharmaceutical compositions containing said compounds. The inventive compounds of general formula (I) are provided with androgenic activity.
Patent CA-2537612-A1 (CA)
Inventor: RUVOLO EDUARDO
IPC: A61K8/97
Filed: 2006-02-24
Abstract: The present invention features compositions comprising at least one compound of the formula I or formula II:    wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof, and the use thereof.
Patent CA-2538403-A1 (CA)
Title: Compositions and methods for treatment of cancer
Inventor: RUBINFELD JOSEPH
IPC: A61K31/16
Filed: 2004-07-13
Abstract: Compositions and methods for treatment of conditions related to the overexpression of EZH2, such as late stage prostate cancer, using a DNA  methylation inhibitor and/or a histone deacetylase inhibitor, optionally in combination with an EZH2 antagonist and/or an antineoplastic agent, to specifically target diseases associated with EZH2 over~expression. Further provided are reagents and kits for treatment of EZH2 overexpression.
Patent CA-2539118-A1 (CA)
Inventor: LECAMPION BRICE TANGUY ALPHONS
IPC: E21B47/02
Filed: 2004-09-16
Abstract: Method and apparatus for estimating a fluid driven fracture volume during hydraulic fracturing treatment of a ground formation. A series of tiltmeters are positioned at spaced apart tiltmeter stations at which tilt changes due to the hydraulic fracturing treatment are measurable by those tiltmeters. Tilt measurements obtained from the tiltmeters at progressive times during the fracture treatment are analysed to produce estimates of the fluid driven fracture volume at each of those times as the treatment is in progress. The analysis may be performed sufficiently rapidly to provide real time estimates of the fluid driven fracture volume and may also produce estimates of fracture orientation. The estimates of fracture volume may be compared with the volume of fluid injected to derive an indication of treatment efficiency.
Patent CA-2541271-A1 (CA)
Inventor: LESTER JOSEPH E
IPC: H01K7/00
Filed: 2006-03-30
Abstract: An incandescent lamp that emits infrared light and a method of making the lamp includes a filament assembly inside a polycrystalline aluminum oxide (PCA) envelope, where the filament assembly preferably has a coiled tungsten filament, solid metal ends of tungsten or molybdenum attached to the coiled tungsten filament, and leads at distal ends of the solid metal ends. End caps are attached to ends of the envelope and have openings through which a respective one of the leads extends, where the leads are each made of an electrically conductive material having a coefficient of thermal expansion compatible with the end caps, such as niobium. The leads are attached to the end caps with glass-ceramic sealing frits. The end caps and sealing frits seal a suitable gas inside the envelope.
Patent CA-2542448-A1 (CA)
Title: Moderating the effect of endotoxins
Inventor: BERGONZELLI GABRIELA
IPC: A23L33/00
Filed: 2004-10-12
Abstract: The present invention relates to the use of an oral composition comprising meat extract and peptones, separately or in combination, in the manufacture of an oral composition to treat the effects of infection by pathogenic bacteria such as Clostridium difficile. Such effects may include the failure of the integrity of the gut epithelial cells and diarrhoea as well as other COX-2 mediated effects.
Patent CA-2542874-A1 (CA)
Inventor: CORMIER MICHEL J N
IPC: A61P9/02
Filed: 2004-10-21
Abstract: The present invention provides methods and compositions for stabilizing dried nucleic acids with carbohydrates such as non-reducing sugars, polysaccharides, and reducing sugars. Preferably, the stabilized nucleic acids are coated on a microprojection member for transdermal delivery. The invention further provides compositions and methods that involve the use of DNase inhibitors to stabilize dried nucleic acids delivered directly into bodily tissues.
Patent CA-2543470-A1 (CA)
Title: An improved combustion apparatus and methods for making and using same
Inventor: OLSTOWSKI FRANEK
IPC: F23D14/62
Filed: 2004-10-21
Abstract: A combustion apparatus (200) is disclosed that improves oxidation efficiency without increasing either combustion apparatus size or residence time, where the apparatus includes a combustion zone (204) having a static mixing zone (208) along a length of the combustion zone.
Patent CA-2543906-A1 (CA)
Title: Heavy oil emulsion stabilizers containing saccharide based emulsion stabilizer
Inventor: SPRAGUE BARRY N
IPC: C09K23/56
Filed: 2004-10-28
Abstract: Heavy oil emulsions, comprising decant oils and No. 6, No. 5 and No. 4 oils, and water are stabilized by adding certain saccharide-based esters.  Preferably, the saccharide-based esters are naturally-occurring saccharide esters such as gallotannins, saponin, red gum, and the like.
Patent CA-2545036-A1 (CA)
Title: Child support with multiple electrical modes
Inventor: ENGLER JAMES R
IPC: A47D13/10
Filed: 2006-04-26
Abstract: A child receiving device is disclosed herein. The device includes a seat pivotally connected to a frame. The device may further include a power transmission line that connects to a remote power source such as an electrical outlet. The transmission line may be hidden within the frame, and may separate when a predetermined amount of force is applied to the line.   The child receiving device further includes an electrical device, an alternating current (AC) power supply connection, a direct current (DC) power supply connection, and a switch that selectively engages either the AC or DC power supply connections. The electrical device may operate in either a first operational mode, in which the power source is an AC power source, or a second operational mode, in which the power source is a direct current (DC) power source. The electrical device may be a motor that drives the motion of the seat.
Patent CA-2545827-A1 (CA)
Inventor: DOHNAL DIETER
IPC: H01H9/00
Filed: 2004-09-14
Abstract: The invention relates to a method for monitoring contact consumption in multiple contact switches of the load-switching type, wherein the selection and the switching is carried out in one step by the movement of switching contacts and which therefore do not have a separate diverter switch. Every time the multiple contact switch is actuated, the load current is measured.  The corresponding, previously stored rated stage voltages for the current switching and information on whether it was shifted "up" or "down", are used to calculate the switching currents of the breaking contacts, the consumption rates are determined on the basis thereof and the volume consumption is accumulated. Said accumulated value is compared with a previously determined threshold value; once this threshold value is reached, warning messages or other messages are generated.
Patent CA-2547997-A1 (CA)
Inventor: NAPIORKOWSKI JOHN J
IPC: H01R29/00
Filed: 2005-03-29
Abstract: A termination module for terminating TELCO wiring and subscriber wiring within a network interface enclosure at a subscriber premises includes a subscriber bridge having burglar alarm connections. The subscriber bridge includes a base, a pair of conductive contact elements disposed within the base and defining a plurality of connection terminals, and a base cap positioned over the base and the contact elements. The termination module provides a demarcation point for electrically disconnecting the subscriber wiring from the subscriber wiring and the subscriber bridge further includes burglar alarm connection points that permit a burglar alarm to be wired in series between the demarcation point and the contact elements such that the subscriber-owned equipment, including the burglar alarm, can be electrically disconnected from the TELCO wiring to fault test a telephone line.
Patent CA-2552049-A1 (CA)
Inventor: TODD BRADLEY L
IPC: E21B43/25
Filed: 2004-12-17
Abstract: The present invention relates to methods and compositions for treating subterranean formations, and more specifically, to improved methods and compositions for generating acids for use downhole, for example, to at least partially degrade the acid-soluble portions of filter cakes deposited in subterranean formations. In one embodiment, the present invention provides a method of degrading an acid-soluble portion of a filter cake comprising contacting the acid-soluble portion of the filter cake with an acid generated from an orthoester.
Patent CA-2554329-A1 (CA)
Title: Pyridinyl - or pyrimidinyl thiazoles with protein kinase inhibiting activity
Inventor: FISCHER PETER
IPC: C07D417/04
Filed: 2005-02-07
Abstract: The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salts thereof, wherein: Z1:1 is N or CH; ;Z2 and Z3 are each independently N or CR7; :Rl, R2, R3, R4, R5, R6, and R7 are each independently H, R8, or R9; each R8 is independently a hydrocarbyl group; and each R9 is independently halo, NO2, alkoxy, CN, CF3, S03H, SO2NR10R11, S02R12, NR13R14 (CH2)aCOOR15, (CH2)bCONR16R17, (CH2)CCOR18 or (CH2)dOH; a, b, c and d are each independently 0, 1 2 3 or 4; R10-18 are each independently H or alkyl; provided that when Rl and R2 are both H, Zl is CH; or Z2 is N; or Zl is CH and Z2 is N; and wherein the compound is other than 4-(4,5-dimethylthiazol-2-yl)-N-(3,4,5~trimethoxyphenyl)-2-pyrimidineamine or 4-(5-(2-hydroxyethyl)-4-methylthiazol-2-yl)~N-(3,4,5-trimethoxyphenyl)-2-pyrimidineamine. Further aspects relate to the use of compounds of formula (I) in the preparation of a medicament for treating one or more disorders selected from a proliferative disorder, a viral disorder, a CNS disorder, diabetes, stroke or alopecia.
Patent CA-2557642-A1 (CA)
Title: Ion channel modulators
Inventor: GALULLO VINCENT P
IPC: A61K31/4164
Filed: 2005-03-07
Abstract: The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of ion channel function, and treatment of disease and disease symptoms, particularly those mediated by certain calcium channel subtype targets.
Patent CA-2557912-A1 (CA)
Inventor: JOBBAGY MIKLOS
IPC: H04M1/253
Filed: 2004-11-02
Abstract: The subject of the invention is a set of equipment for secure direct information transfer over the Internet, which contains information transmitting terminal devices suitable for collaborating with an information forwarding network, taking part in the information traffic, the individual information transmitting terminal devices are equipped with a sender partial unit, a receiver partial unit and a storage partial unit comprising an ID-register containing a device identification signal, a C-register suitable for storing a coding key and a D-register suitable for storing a decoding key, where the C-register containing the coding key is in connection with the sender partial unit, and a coding key and a collaborating decoding key are allocated to the individual information transmitting terminal devices. The characteristic of the invention is that the storage partial unit (11) of each information transmitting terminal device (10) is completed with one or more temporary storage registers (15) for the temporary storage of the coding keys (26) of other information transmitting terminal devices (20), while the information forwarding network (30) is completed with at least one central traffic co-ordinating unit (40), the central traffic co-ordinating unit (40) has an MD-register (42) storing a master decoding key (42a) and a memory unit (43) containing base cells (43a, 43b) for storing the coding keys (16, 26) belonging to the individual information transmitting terminal devices (10, 20) and a master coding key (41a) collaborating with the master decoding key (42a) is allocated to the central traffic coordinating unit (40), and the C-registers (13a, 23a) of the information transmitting terminal devices (10, 20) are provided with a master coding key (41a) collaborating with the master decoding key (42a) stored in the MD-register (42) of the central traffic co-ordinating unit (40).
Patent CA-2558983-A1 (CA)
Title: Apparatus and method for measuring biological information
Inventor: HONG HYUNG-KI
IPC: A61B6/00
Filed: 2006-09-06
Abstract: An apparatus and method for precisely measuring various biological information of a user's body by using a single measuring apparatus enable precisely and effectively measuring biological information including body fat, pulse and a blood vessel aging degree. By measuring an infrared absorbance or infrared rays irradiated to a measurement target according to a modulation and tuning method and obtaining the information with reference to supplementary biological information obtained from a user, the plurality of biological information can be precisely measured at a low driving voltage through the modulation and tuning method by using a single infrared light source. Also, the measuring apparatus can be reduced in size by simplifying its construction and can be effectively integrated into various devices.
Patent CA-2561121-A1 (CA)
Title: Methods for conditioning plant somatic embryos
Inventor: GROB JAMES A
IPC: A01C1/00
Filed: 2006-09-27
Abstract: The present invention provides methods for conditioning plant somatic embryos. The methods include the step of exposing the somatic embryos to a gas stream having a selected moisture content for a period of time sufficient to change the moisture content of the somatic embryo to a desired moisture content, wherein the gas stream is produced using an ionomeric membrane.
Patent CA-2561414-A1 (CA)
Title: Hardener for epoxy resin and epoxy resin composition
Inventor: USUI TAKETOSHI
IPC: C08G59/18
Filed: 2005-03-30
Abstract: An amine hardener for epoxy resins which comprises an amine adduct (A) and a low-molecular amine compound (B) as major components, wherein the molecular weight distribution of the amine adduct (A), which is defined by the ratio of the weight-average molecular weight to the number-average molecular weight, is 3 or lower and the low-molecular amine compound (B) is contained in an amount of 0.001 to 1 part by mass per 100 parts by mass of the amine adduct (A).