baber/WOPTO huggingface dataset:
Patent CA-2552107-C (CA)
Title: Pyrrolotriazine compounds as kinase inhibitors
Inventor: FINK BRIAN E
IPC: A61P35/00
Filed: 2004-12-23
Granted: 2011-10-18
Abstract: The present invention provides compounds of formula (I); and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula (I) compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
Patent CA-2558661-C (CA)
Title: Load bearing biocompatible device
Inventor: BOYAN BARBARA D
IPC: A61L27/56
Filed: 2005-02-07
Granted: 2012-09-04
Abstract: Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided are implants suitable for load-bearing surfaces in hard tissue repair, replacement, or augmentation, and to methods of their use. One embodiment of the invention relates to an implantable spinal disc prosthesis.
Patent CA-2560529-C (CA)
Title: Cerebrum evaluation device
Inventor: SHIOMI KAKUICHI
IPC: A61B5/16
Filed: 2004-04-28
Granted: 2012-06-26
Abstract: There is provided a cerebrum evaluation device for evaluating the state of the cerebrum of a subject by analyzing a speech signal of the subject by using chaotic signal processing utilizing the periodicity of the signal. The cerebrum evaluation device evaluates the state of the cerebrum according to the speech signal uttered by the subject. The cerebrum evaluation device includes: a statistic information database containing chaotic index values of speech signals of a plurality of subjects; a speech signal acquisition unit for acquiring a speech signal; a chaotic index value calculation unit for calculating a chaotic index value of the speech signal by the chaotic signal processing utilizing the periodicity of the speech signal acquired; an evaluation unit for evaluating the state of the cerebrum of the subject according to the calculated chaotic index value by referencing the statistic information database;  and an output unit for outputting the result evaluated by the evaluation unit.
Patent CA-2561131-C (CA)
Title: Damping for electromechanical actuators
Inventor: EDSON RALPH D
IPC: G05B19/404
Filed: 2004-12-10
Granted: 2012-03-13
Abstract: Oscillation and other disturbance damping is provided for a system having a load driven by an electric motor. Damping is achieved using feedback in an active mode, where power is supplied in a normal operation mode of the electromagnetic actuator. A gear train or other mechanical advantage device is connected between the electromagnetic actuator output and a load, to form an electromagnetic actuator. Feedback is provided by measured force or torque transmitted between the actuator and load mass. In active damping, a high pass filter is used to receive feedback signals and filter out low frequency feedback. The motor coils of the motor are shorted, such as by using a switch.  The induced motor current acts to inhibit load oscillations. A number of resistors are in the short circuit to tailor the damping characteristics of the motor.
Patent CA-2573955-C (CA)
Title: Improvements for control of exhaust systems
Inventor: LIVCHAK ANDREY
IPC: F24C15/20
Filed: 2005-07-25
Granted: 2013-12-17
Abstract: Exhaust capture and containment are enhanced by means of automatic or manual side skirts, a sensitive breach detector based on interference effects, a combination of vertical and horizontal edge jets, and/or corner jets that are directed to the center diagonally from corners. Associated control functions are described.
Patent CA-2576300-C (CA)
Inventor: BECKER HEIKE
IPC: C11D1/72
Filed: 2005-09-13
Granted: 2013-12-24
Abstract: The invention relates to a phosphate-free cleaning formulations for a dish cleaning machine containing the following components: (a) 1-20 % by weight hydrophobically modified polycarboxylate, (b) 1-50 % by weight complexing agent selected from a nitrile-triacetic acid, triacetic acid hydroxyethylethylendiamine, tetracetic acid ethylenediamine, pentacetic acid diethylenetriamine, diacetic acid methylglycyne, glutaminic acid diacetic acid, iminodisuccinic acid, iminodisuccinic acid hydroxymine, disuccinic acid ethylenediamine, asparaginic acid diacetic acid and salts thereof group, (c) 1-15 % by weight non-ionic low-foaming detergents, (d) 0.1-30 % by weight bleaching and optionally a bleaching activator, (e) 0-60 % by weight additional detergents, (f) 0-8 % by weight enzymes, (g) 0-50 % by weight one or several types of additives, wherein from (a) to (g) is equal to 100 % by weight.
Patent CA-2584465-C (CA)
Title: Heterocyclic carbonyl compounds and their use as sgk-inhibitors
Inventor: DORSCH DIETER
IPC: C07D263/34
Filed: 2005-04-04
Granted: 2013-08-06
Abstract: The invention relates to novel heterocyclic compounds of formula (I):  (see formula I) in which R1 and R1a independently are an optionally substituted mono- or bicyclic saturated, unsaturated or aromatic carbo- or heterocycle; D is O, NH or S; W  is CX or N; T and T' are CX, N or CR, with the proviso that T and T' are not both CR; R  is -C(=O)-N(R2)[C(R2)2]n R1a; X is H, Hal, A, OR2, N(R2)2, NO2, CN, COOR2, CON(R2)2, NR2COA, NR2SO2A, COR2 or SO2NR2; R2 is H, A, -[C(R3)2]n-Ar', -[C(R3)2]n-Het', -[C(R3)2]n-cycloalkyl, -[C(R3)2]-OR3, -[C(R3)2]n-COOA or -[C(R3)2]n N(R3)2; R3 is H  or A; A is optionally branched and modified C1-10 alkyl; Ar' is optionally substituted phenyl, naphthyl or biphenyl; Het' is an optionally substituted mono- or bicyclic saturated, unsaturated or aromatic heterocycle; Hal is F, CI, Br or I, and n is 0, 1, 2 or 3. Said compounds are SGK-inhibitors and can be used in the treatment of SGK-related diseases and disorders such as diabetes, obesity, metabolic syndrome (dyslipidemia), systemic and pulmonal hypertension, cardiovascular diseases and renal diseases, and generally for any kind of fibroses and inflammatory processes.
Patent CA-2586495-C (CA)
Inventor: NORGAARD RAYMOND
IPC: D06C15/02
Filed: 2005-11-03
Granted: 2013-07-16
Abstract: The invention relates to an apparatus for producing nonwoven, fleece-like fiber products, said apparatuus comprising a transfer belt configured to transport an intermediate product on the underside of a transfer belt to a roller arrangement, said roller arrangement comprising four rotatable rollers that are arranged and configured to interact in pairs in constellations that can be selectively modified, wherein each of the four rollers has a rotational axis, and the four rotational axes run at least approximately parallel to each other.
Patent CA-2593140-C (CA)
Title: Inhibiteur ou promoteur de l'uridinediphosphate-glucuronosyltransferase2b (ugt2b)
Inventor: HU OLIVER YOA-PU
IPC: A61P25/04
Filed: 2005-12-13
Granted: 2013-08-13
Abstract: La présente invention concerne un inhibiteur de l'UGT2B qui peut augmenter la biodisponibilité des médicaments. L'inhibiteur de l'UGT2B est choisi parmi la capillarisine, l'isorhamnétine ou la ß-naphtoflavone, etc., ou leurs combinaisons, sous la forme de base libre ou des sels pharmaceutiquement acceptables. La présente invention concerne également un promoteur de l'UGT2B qui peut favoriser la fonction individuelle d'élimination des toxines du foie. Le promoteur de l'UGT2B est choisi parmi l'acide nordihydroguaïarétique, la wogonine, l'acide trans-cinnamique, etc., ou leurs combinaisons, sous la forme de base libre ou des sels pharmaceutiquement acceptables.
Patent CA-2600315-C (CA)
Inventor: KEUCHEL KENNETH
IPC: D04H3/009
Filed: 2005-03-07
Granted: 2012-08-14
Abstract: L'invention concerne une matrice adhésive polymère et un procédé de production de celle-ci, la matrice comprenant soit: 1) un polymère de Nylon 12 ou 11 comprenant une toile non tissée à épaisseur sensiblement uniforme ou des mélanges de ceux-ci, avec jusqu'à 40 % en poids d'un autre matériau polymère thermoplastique compatible; soit 2) une matrice fibreuse ou non fibreuse d'épaisseur sensiblement uniforme comprenant un polyamide à terminaison amine et à faible absorption d'humidité, de préférence, un polymère de Nylon 12 ou 11 à terminaison amine ou des mélanges de ceux-ci, avec jusqu'à 40 % en poids d'un autre matériau polymère thermoplastique compatible. L'invention concerne également un laminé composite multicouche comprenant au moins une couche de la matrice adhésive polymère selon l'invention positionnée entre une pluralité de couches fibreuses de renfort imprégnées d'une résine de liant et un procédé de production d'un tel laminé composite multicouche.
Patent CA-2602308-C (CA)
Inventor: TOERRING DITTE
IPC: A01K63/02
Filed: 2006-03-22
Granted: 2013-05-21
Abstract: A system for transporting live aquatic animals between shipping points, said system comprising water filled tank units 300 for containing the live animals in a life supporting aquatic environment during the transport; and a refrigerated marine container 200 provided with means 240, 250, 260 for cooling, aerating and circulating the water in said tank units at least during the transport; said system further comprising docking stations 100 situated at said shipping points, said docking stations comprising docking means for receiving said refrigerated marine container 200 containing said tank units 300; and means 120, 130, 140 for providing a life supporting aquatic environment for the live aquatic animals in said tank units 300 placed in said refrigerated marine container 200 while the refrigerated marine container 200 is attached to the docking station 100.
Patent CA-2604857-C (CA)
Inventor: BLISS PETER L
IPC: B01D53/053
Filed: 2006-04-04
Granted: 2015-06-30
Abstract: A portable oxygen concentrator includes a pair of sieve beds having first and second ends, a compressor for delivering air to the first ends of the sieve beds, a reservoir communicating with the second ends of the sieve beds, and an air manifold attached to the first ends of the sieve beds. The air manifold includes passages therein communicating with the compressor and the first ends of the sieve beds. A set of valves is coupled to the air manifold, and a controller is coupled to the valves for selectively opening and closing the valves to alternately charge and purge the sieve beds to deliver concentrated oxygen into the reservoir. An oxygen delivery manifold communicates with the second ends of the sieve beds for delivering oxygen from the reservoir to a user. Pressure sensors may be provided in the reservoir and/or delivery line for controlling operation of the controller.
Patent CA-2609367-C (CA)
Title: Safflower with elevated gamma-linolenic acid
Inventor: KNAUF VIC C
IPC: A23L33/00
Filed: 2006-05-22
Granted: 2014-08-19
Abstract: The present invention relates to compositions and methods for preparing gamma-linoleic acid (GLA) in safflower plants, particularly from seeds of safflower.  Nucleic acid sequences and constructs encoding one or more fatty acid desaturase sequences are used to generate transgenic safflower plants that contain and express one or more of these sequences and produce high levels of GLA in safflower seeds. Provided are transgenic safflower plants and seeds that produce high levels of GLA. Additionally provided are oils produced from seeds of this invention. The invention also relates to methods of treating a variety of diseases including nervous system disorders, inflammatory conditions, cancer and cardiovascular disorders using the oils of this invention.
Patent CA-2616277-C (CA)
Title: Marqueurs urinaires permettant de detecter un cancer de la vessie
Inventor: GUILFORD PARRY JOHN
IPC: G01N33/577
Filed: 2005-07-22
Granted: 2023-03-07
Abstract: La détection précoce des tumeurs a une importance primordiale pour la survie de patients atteints d'une tumeur, notamment d'une tumeur de la vessie. Des éléments de la famille des BTM ou des UBTM peuvent s'accumuler en grande quantité et de manière constante dans le tissu tumoral de la vessie et d'autres tissus tumoraux, et/ou dans l'urine des patients, et constituent ainsi des marqueurs du cancer de la vessie et d'autres types de cancer. Dans certains modes de réalisation, lorsque les BTM ou UBTM s'accumulent dans l'urine, la détection d'éléments de la famille des UBTM peut constituer une technique diagnostique efficace. Dans des modes de réalisation, les procédés PCR quantitatifs s'avèrent plus performants que les procédés faisant appel aux microréseaux. Dans d'autres modes de réalisation, la détection et la quantification d'une pluralité de BTM ou d'UBTM peuvent améliorer la sensibilité et la spécificité de la détection du cancer de la vessie, ce qui permet de disposer de procédés visant à déterminer le stade et le type du cancer de la vessie. L'invention concerne également des kits permettant une mise en oeuvre facile et pratique des procédés selon l'invention.
Patent CA-2627805-C (CA)
Title: Candleholder with a melting plate alignment feature
Inventor: KUBICEK CHRIS A
IPC: F21V35/00
Filed: 2006-11-02
Granted: 2011-05-24
Abstract: A candleholder (500) for a fuel element (110) , such as a votive candle, includes a melting plate (504) carried by a base portion (502) . The melting plate (504) is generally dish-shaped and disposed within a generally complementarily shaped recess (506) in a top end of the base portion (502). An alignment mechanism including an inner peripheral step (522) protruding into the recess and a complementary ledge (526) in a bottom surface of the melting plate (504) helps ensure that the melting plate is disposed at a predetermined position in the recess. The ledge (526) rests on the peripheral step (522) with an adhesive (166) disposed therebetween when the melting plate is in the predetermined position. A ring protrusion (530) from the base portion is disposed under a cavity (532) defined under a capillary lobe in the melting plate. The ring protrusion helps retain a magnet (528) in a predetermined location in the cavity and may also serve as part of the alignment mechanism.  The magnet may be used to help retain a ferro-magnetic wick holder of the votive candle on the capillary lobe .
Patent CA-2628637-C (CA)
Title: Rotary cutter device with integrated cooling system
Inventor: SHINN RICKEY D
IPC: B02C18/06
Filed: 2008-04-07
Granted: 2011-08-09
Abstract: A hydraulic cutter device incorporates a rotatable base including a plurality of spaced cutter teeth. A protective shield covers at least a portion of the base. A fluid cooler is located adjacent the protective shield, and defines a window for movement of ambient air from a relatively high-pressure area upstream of the fluid cooler to a relatively low-pressure area downstream of the fluid cooler. A hydraulic motor is adapted for rotating the base, and includes a plurality of hydraulic lines communicating with the fluid cooler. Rotation of the base creates a pressure reduction downstream of the fluid cooler causing ambient air flow into and through the fluid cooler to cool fluid moving into and from the hydraulic motor.
Patent CA-2628774-C (CA)
Title: Prise combinee pour un dispositif d'exercice
Inventor: HETRICK RANDAL
IPC: A63B21/002
Filed: 2006-11-07
Granted: 2013-08-20
Abstract: L'invention concerne un dispositif d'exercice présentant beaucoup de caractéristiques avantageuses, y compris la possibilité d'offrir à l'utilisateur une combinaison de prises et la possibilité de monter facilement le dispositif au mur. Un dispositif d'exercice décrit est un dispositif à résistance inélastique comportant une prise combinée qui comprend des prises de main et une boucle. On peut utiliser la prise de main et la boucle comme prise de pied ou bien n'utiliser que la prise de main pour la main. Le choix d'un accessoire de prise spécifique permet à l'utilisateur d'exercer des parties spécifiques de son corps et offre un plus grand nombre d'exercices possibles.
Patent CA-2637426-C (CA)
Inventor: HUMPHRIES GARY W
IPC: B65D25/14
Filed: 2008-07-10
Granted: 2014-09-23
Abstract: A thermal insulating liner for a container lid has a top sheet and a bottom sheet spaced by a core. The bottom sheet has an exterior metal foil layer. A side edge-to-side edge transverse cut line extends through the bottom sheet proximate each of two opposed ends of the liner. The liner has reduced thickness end margins extending between each said side edge-to-side edge transverse cut line and each of the opposed ends. A die to make the lid liner has a central well and, proximate each end of the die, an upward step to a land with an inside edge of the step having a ramp surface. A first cutting blade protrudes upwardly from the land and a second cutting blade protrudes upwardly above the land at each end of the die and above the level of the first cutting blade.
Patent CA-2639390-C (CA)
Inventor: JOBARD THIERRY
IPC: B60L7/08
Filed: 2008-09-02
Granted: 2017-05-09
Abstract: This device is an electrical safety brake designed for an electrical traction vehicle, in particular a rail vehicle, including a turning electromechanical machine (10) with permanent magnets having at least one coil with electrical terminals (13, 14, 15), a braking torque production (22) resistor device, an electromechanical switch (20) capable of safely connecting the electrical terminals (13, 14, 15) of the machine (10) to the braking torque production (22) resistor device. It is characterised in that the braking torque production (22) resistor device includes on the one hand a bipolar assembly (122) with at least one dissipation resistance, the assembly having two unique connection terminals and forming a common bipolar electrical charge flow terminal for all the terminals on the machine (13, 14, 15) and on the other hand the means to convert (120) currents from all the terminals (13, 14, 15) of the machine into a single current delivered to two unique terminals of the assembly with at least one dissipation resistance, the said conversion means (120) being exempt of active power switches.
Patent CA-2642612-C (CA)
Inventor: O'KEEFFE ERIC
IPC: B07B1/00
Filed: 2007-02-16
Granted: 2015-04-21
Abstract: A mobile material screening apparatus (100) for separating bulk particulate material into groups of particles of differing sizes comprises a support chassis (2), a horizontal screen box (3) housed within the support chassis (2) and an additional inclined pre-screening module (50) which is adapted to be demountably attached to the support chassis (2). The mobile screening apparatus (100) comprises five outputs. Foldable conveyors (7a, 8, 9, 910, 920) can be deployed outwardly from and stowed inwardly against the material screening apparatus. The provision of an inclined pre-screening module (50) provides relief to the horizontal screen box (3) by first removing the larger sized particles from the bulk material which can be returned to a crusher for recycling and serves also to increase the total number of grades of material separated by the screening apparatus.
Patent CA-2648568-C (CA)
Title: Orthogonal resource reuse with sdma beams
Inventor: DONG MIN
IPC: H04W16/02
Filed: 2007-04-20
Granted: 2012-09-25
Abstract: A wireless communication system can implement beamforming across multiple omni-directional antennas to create beams at different spatial directions. The communication system can arrange the beams in sets, with each set arranged to provide substantially complete coverage over a predetermined coverage area. The communication system can arrange the multiple SDMA beam sets to support substantially complementary coverage areas, such that a main beam from a first set provides coverage to a weak coverage area of the second beam set. The wireless communication system assigns or otherwise allocates substantially orthogonal resources to each of the beam sets. The wireless communication system allocates resources to a communication link using a combination of beam sets and substantially orthogonal resources in order to provide improved coverage without a corresponding increase in interference.
Patent CA-2648700-C (CA)
Title: Underbody thermal blanket
Inventor: PIERRE JOSEPH
IPC: A61F7/00
Filed: 2007-04-09
Granted: 2014-06-17
Abstract: An inflatable convective thermal blanket is designed to have at least one section on its top surface that has securely mounted thereon at least one fluid absorbent mechanism for absorbing fluids from a subject that is placed onto the blanket, or from fluids fallen onto the blanket from other sources. The one section is configured onto the blanket in such a way that it forms a well for collecting the fluids. The fluid absorbent mechanism, which may be in the form of a pad, would absorb the collected fluid to thereby minimize evaporative and cooling effects on the subject. Instead of mounting it on top of the blanket, the fluid absorbent pad may be mounted to the underside of the blanket, with appropriate holes and/or openings provided at the fluid collecting section, so that the collected fluids are drained onto the fluid absorbent pad. To enhance the input flow of air to the blanket, as well as to enable the blanket to be flatly folded for storage or shipping, a collapsible retainer mechanism is provided at the input port(s) of the blanket. The retainer mechanism opens up to a shape that facilitates the mating of an air hose to the input port. When folded to its collapsed position, the retainer mechanism, and the input port, would lie substantially coplanarly with the blanket. When configured to the position for accepting the air hose, the retainer mechanism is positioned substantially orthogonal to the blanket.
Patent CA-2648733-C (CA)
Title: Two step preparation of random polyoxadiazole copolymer and articles resulting therefrom
Inventor: LEE KIU-SEUNG
IPC: C08G73/08
Filed: 2007-04-26
Granted: 2014-10-28
Abstract: In a preparation of random polyoxadiazole copolymer by reaction of a mixture of oleum, hydrazine sulfate, terephthalic acid, and isophthalic acid, the improvement requires the addition of oleum in more than one step.
Patent CA-2649519-C (CA)
Inventor: LENZE FRANZ-JOSEF
IPC: B21D22/20
Filed: 2007-04-24
Granted: 2014-05-20
Abstract: A method for the press-hardening and tempered forming of blanks from high and/or very high strength steels is described. The blank is heated at least to austenitising temperature before the forming and then hot-formed in a forming tool, wherein the forming tool has a means for tempering. The blank is formed by means of contact surfaces of forming tool elements provided in the forming tool for forming. The contact surfaces are at least partially allocated to a plurality of temperature zones provided in the forming tool and a plurality of temperature zones of the forming tool is tempered during the forming by way of tempering means, in each case to pre-defined temperature values.
Patent CA-2651536-C (CA)
Title: Method and apparatus for inspecting joined object formed by friction stir joining
Inventor: OKAUCHI HIRONORI
IPC: B23K20/12
Filed: 2007-03-19
Granted: 2012-08-07
Abstract: This invention provides a method for inspecting a joined region and joining strength of a joined object formed by a spot friction stir joining process. In this method, an ultrasonic wave is introduced into the joined object from a backing face 25 opposed to a joining tool plunging face 24 and the ultrasonic wave reflected from the joined object 20 is taken in. In this case, the joining region 21 and the joining strength is estimated by observing a reflected wave of the ultrasonic wave in the vicinity of a position, along a reference direction Z, corresponding to an interface 27 of two joining members, without using the reflected wave of the ultrasonic wave reflected from the joining tool plunging face, thereby inspecting the joined object based on the estimation result. Thus, influence of a concave/convex shape of a joining mark 29 formed in the joining tool plunging face 24 can be avoided, and. the use of the ultrasonic wave for estimating the joined region 21 can achieve an inspection of joining quality without destroying the joined object 20.