baber/WOPTO huggingface dataset:
Patent CZ-293253-B6 (CZ)
Title: Process for preparing a drug carrier comprising particles of a pure active compound that is insoluble or only sparingly soluble in water, and the drug carrier per se
Inventor: MULLER RAINER H
IPC: C09K23/56
Filed: 1995-11-09
Abstract: Provided is a process for preparing a drug carrier comprising particles of a pure active compound which is insoluble or moderately soluble in water, or particles of a mixture of at least two compounds exhibiting such activity, wherein the active components are solid at room temperature. The preparation process is characterized in that a suspension of the active substance or a mixture of active substances are subjected to homogenization within a piston-gap homogenizer to form particles having average diameter, determined by photon correlation spectroscopy of 10 nm to 1,000 nm, whereby the proportion of particles larger than 5 microns in the total population being less than 0.1 percent (number distribution determined with a Coulter counter). Further disclosed is a drug carrier comprising particles of a pure 4-[N-(2-hyroxy-2-methylpropyl)ethanolamine]-2,7-bis-(cis-2,6-dimethylmorpholin-4-yl)-6-phenylpteridine, carbamazepine, tetracaine or prednisolone, having the above-specified average diameter and particle proportion.
Patent CZ-289923-B6 (CZ)
Title: Hepatitis C virus, shortened asialoglycoprotein, pharmaceutical composition containing thereof and its use
Inventor: RALSTON ROBERT O
IPC: C07K14/18
Filed: 1997-07-10
Abstract: In the present invention there is described hepatitis C virus i.e. HCV, a shortened asialoglycoprotein being selected from the group comprising asialoglycoprotein exprimed from E1 HCV region, which comprises deletion of a portion of a sequence being located within the region of amino acids 330 to 380 of E1 region numbered from the beginning of the HCV polyproteins and asialoglycoprotein exprimed from E2 HCV region, which comprises deletion of a portion of a sequence being located within the region of amino acids 660 to 830 of the E2 region numbered from the beginning of the HCV polyproteins. The invention further describes a pharmaceutical composition containing this asialoglycoprotein as well as its use for immunodiagnostic method for detection of antibodies against HCV.
Patent CZ-291386-B6 (CZ)
Title: Quinazoline derivatives functioning as VEGF inhibitors, process of their preparation and pharmaceutical preparations in which they are comprised
Inventor: THOMAS ANDREW PETER
IPC: C07D239/93
Filed: 1997-02-10
Abstract: The present invention relates to a quinazoline derivative of the general formula I wherein: Z represents -O-, -NH- or sulfur; m is an integer from 1 to 5; Re1 represents hydrogen, a hydroxy group or an alkoxy group containing 1 to 3 carbon atoms; R2 represents hydrogen; Re3 represents a hydroxy group, a halogen, an alkyl group containing 1 to 3 carbon atoms, an alkoxy group having 1 to 3 carbon atoms a trifluoromethyl group or a cyano group; Xe1 represents -O-, -CHi2-, -NRe7-, or -NRe8CO, (wherein Re7, and Re8 each represents hydrogen); Re4 represents a group which is alkenyl, alkynyl or optionally substituted alkyl, which alkyl group may contain a heteroatom linking group, which alkenyl, alkynyl or alkyl group may carry a terminal optionally substituted with 5 or 6 membered saturated heterocyclic group; and salts thereof, processes for their preparation, pharmaceutical compositions containing the quinazoline derivative of the general formula I or pharmaceutically acceptable salts thereof as active component. The quinazoline derivatives of the general formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent CZ-288165-B6 (CZ)
Title: Expansion joint for part of a railway track
Inventor: BENENOWSKI SEBASTIAN
IPC: E01B11/42
Filed: 1993-05-07
Abstract: The invented expansion joint (276, 278) for part of a railway track arranged on a bearing plate (214) has a first fixedly laid rail section and a second rail section that is slidable with respect to the first rail section, whereby the second rail section bears through the mediation of an area (B) against the firs section being provided with a curvature, whereby after loading said second rail section with transverse forces during sliding thereof, the free front end thereof follows a bending line (P). The curvature radius of the first, fixedly laid rail section corresponds in that area (B) against which the sliding second rail section bears to the sliding second rail section bending line (P).
Patent CZ-293719-B6 (CZ)
Title: Process for controlling amount of sialic acid present in glycoprotein produced by mammalian cell culture
Inventor: ETCHEVERRY TINA
IPC: A61K38/00
Filed: 1996-06-06
Abstract: In the present invention, there is described a process for controlling the amount of sialic acid present on an oligosaccharide side chain of a glycoprotein produced by mammalian cell culture which comprises: culturing the mammalian host cell in a production phase of the culture which is characterized by addition of  an alkanoic acid or a salt thereof to the cell culture at a concentration of about 0.1 mM to about 20 mM and maintaining the osmolality of the cell culture at about 250 to about 600 mOsm at a temperature of the cell culture maintained within the range of 30 to 35 degC. Described is also composition containing chimeras having adjusted amount of sialic acid.
Patent SK-281272-B6 (SK)
Title: Apparatus and method for packaging cheese
Inventor: MELI VINCENT A
IPC: B65B9/067
Filed: 1992-05-11
Abstract: An apparatus and method are provided for forming a hermetically sealed package for a slice of a food item. A web of thermoplastic material is first formed into a tubular arrangement with a hermetic longitudinal seal. To form the tubular arrangement, means are provided for folding a continuous web of thermoplastic material into V-folded condition and for continuously forming a hermetic seal along the open longitudinal edge of the V-folded web. The hermetic seal is formed between the inner surfaces of the front and rear faces of the web to define a tubular web member. The food item which has been formed into a soft mass, is then inserted into the tubular member and the tubular member is flattened to form a thin film tube. Means are provided for forming a hermetically sealed cross-seal which are disposed substantially transverse to the longitudinal forward moving direction of the web.
Patent SK-282107-B6 (SK)
Title: A method for manufacturing a material suitable for use as a top sheet of an absorbent disposable article, and one such material
Inventor: EKDAHL JOAKIM
IPC: B29C51/14
Filed: 1993-05-18
Abstract: PCT No. PCT/SE93/00442 Sec. 371 Date Nov. 18, 1994 Sec. 102(e) Date Nov. 18, 1994 PCT Filed May 18, 1993 PCT Pub. No. WO93/22995 PCT Pub. Date Nov. 25, 1993In a method of manufacturing material suitable for use as a top sheet in an absorbent disposable article, such as a sanitary napkin, an incontinence guard or a diaper, a laminate (1) comprised of a plastic film (2) and a layer of non-woven material (3) on at least one side of the plastic film is applied to a perforated supportive device (6) with one layer of non-woven material facing towards the supportive device. The plastic film is heated to a temperature above its softening temperature and there is generated between the two mutually opposing sides of the laminate a pressure difference of such magnitude that the plastic film will rupture within the regions of the holes in the supportive device so as to form openings (10) which lead to the associated non-woven material. A soft and smooth, liquid-permeable top sheet material is achieved.
Patent SK-278807-B6 (SK)
Title: Powder-actuated fastening tool
Inventor: FROMMELT MARKUS
IPC: B25C1/00
Filed: 1992-11-05
Abstract: Powder-actuated fastening tool consists of the shell (1) and the handle (7), where the guiding channel (9) is created and this channel is being used for inserting the band catridge (8) with hubs (8a) and this catridge is in a perpendicular direction related to the barrel axis. In the guiding channel (9), there are located the means (10) used for moving and the means preventing backward running for snap into the relives (8e), created on the longitudinal margins of the catridge (8). In a space of the catridge (8) input into the channel (9), there are created tow blocking mechanism in the opposite direction of each other, however they are located in the direction (x) closed to the catridge (8) moving, before means used for moving and before means (15) to prevent backward running and they are forcing into the cross-section of the guiding channel (9), and the orientation of sides is the same like the orientation of the longitudinal catridge (8) margins. The longitudinal dimension of the blocking mechanisms (13, 14). On the guiding end of the catridge (8), there are created guiding curves used to draw out the blocking mechanisms (13, 14) and these curves are created based on the elastic walls of the guiding channel (9) and they have the holding cams (13b, 14b) together with the blocking bossages (13a, 14b), located before the holding cams (13b, 14b), in the direction (x) related to the catridge motion, the contour of which is created by segment of a circle, in principle.
Patent SK-277724-B6 (SK)
Title: N-succinoyl-2-ethyl-6-methylaniline and method of its preparation
Inventor: SIDOOVA EVA
IPC: C07C227/14
Filed: 1989-10-16
Abstract: It was prepared till now unknown N-succinoyl-2-ethyl- -6-methylaniline formula I. Synthesis of this compound is realized by reaction 2-ethyl-6-methylaniline with anhydride cuccinic acid in benzene by reflux. The compound is antihelminic effective against model helmints Nippostrongylus brasiliensis and Hymenolepis nana.
Patent CZ-295192-B6 (CZ)
Title: Centrifugal jig
Inventor: KELSEY CHRISTOPHER GEORGE
IPC: B04B3/00
Filed: 1998-08-20
Abstract: In the present invention, there is disclosed a centrifugal jig having a container mounted for rotation about its longitudinal axis (22) the container having an axial region and a peripheral region separated from the axial region (32) by ragging material (41) which is radially restrained by a screen (30).  The peripheral region is composed of a series of hutch chambers (34) with reciprocating wall portions (45) located radially outside the screen (30), for repetitively dilating the ragging (45). Also disclosed is a hutch chamber (34)  construction applicable to both rotary and non-rotary jigs, having a reciprocating wall portion (45) which includes convergent wall surfaces leading to the hutch chamber (34) concentrate outlet (44).
Patent CZ-298862-B6 (CZ)
Title: Estrogen compound
Inventor: MILLER CHRISTOPHER PAUL
IPC: A61P3/06
Filed: 2000-09-11
Abstract: The present invention discloses tissue selective estrogen compounds of the general formula I wherein: Ri1 and Ri2 represent independently on each other, hydrogen, alkyl chain having 1 to 6 carbon atoms, benzyl, acyl containing 2 to 7 carbon atoms, benzoyl, (1) or (2); X denotes hydrogen, alkyl containing 1 to 6 carbon atoms, CN, halogen, trifluoromethyl, or thioalkyl having 1 to 6 carbon atoms; n is 1 through 3; with the proviso that at least one of Ri1 or Ri2 denotes (1) or (2). The above-described compounds are suitable for treating conditions such as bone loss or osteoporosis, osteoarthritis, hypocalcaemia, Paget's disease, osteomalacia and multiple myeloma. The compounds are also suitable for antiestrogen therapy.
Patent CZ-300686-B6 (CZ)
Title: Method for reducing amount of escitalopram-N-oxide in free escitalopram or its salt
Inventor: DANCER ROBERT
IPC: A61K31/343
Filed: 2006-06-22
Abstract: In the present invention, there is disclosed a method for reducing amount of escitalopram-N-oxide in free escitalopram or a salt thereof consisting in that the free escitalopram is dissolved in diethyl ether and escitalopram-N-oxide is removed as a solid material.
Patent CZ-304190-B6 (CZ)
Title: Application method of water-soluble clear lacquer to metallurgical product
Inventor: PODJUKLOVA JITKA
IPC: C09D4/02
Filed: 2012-12-11
Abstract: The present invention relates to a method of applying water-soluble clear lacquer containing 75 to 80 percent by weight of acrylate dispersion, 4.75 to 5.75 percent by weight of additive for wettability, dispersion and non- frothiness, 0.1 to 0.2 percent by weight of corrosion inhibitor, 2 to 10 percent by weight of a cross linking agent based on water-soluble zinc oxide complex, 0.5 to 2.0 percent by weight of on water-soluble organic corrosion inhibitor based on a mixture of potassium octadecanoate, tripotassium phosphate and 2,2,2´´-nitriloethanol, 5 to 10 percent by weight of anticorrosive pigment based on calcium and manganese oxyaminophosphate complex, and water to a metallurgical product, wherein the method is characterized in that the metallurgical product is preheated to a temperature in the range of 38 to 45 degC, followed by spraying under air pressure of 0.2 to 0.4 MPa a lacquer diluted by 10 to 15 percent by weight of water. Subsequently, the metallurgical product with lacquer applied thereto is freely dried in air for a period of 10 minutes at ambient temperature followed by drying at a temperature ranging from 68 to 78 degC for a period of 30 minutes. Then it is freely cooled down in air at ambient temperature. The invention further relates to a metallurgical product comprising on its surface a layer obtained by drying the lacquer, which layer has a dry transparent thickness in the range of 50 to 70 microns with a nano layer of iron compounds with thickness in the range of 25 to 50 microns.
Patent CZ-308465-B6 (CZ)
Title: Crankcase with a crankcase ventilation assembly
Inventor: PÁV KAREL
IPC: F01M13/02
Filed: 2019-07-09
Abstract: A crankcase with a crankcase ventilation assembly that also allows crankcase pressure to be reduced at low intake manifold pressure during low engine load and includes the crankcase (1), at least one cylinder (2), an air inlet (3), a pressure valve (4) and an intake manifold (5) comprising a throttle valve (6). The air inlet (3) is connected to at least one cylinder (2) via the intake manifold (5), and the crankcase (1) is connected to the intake manifold (5) behind the throttle valve (6) and to the intake manifold (5) in front of the throttle valve (6). The pressure valve (4) is located in the connection between the crankcase (1) and the intake manifold (5) behind the throttle valve (6). The assembly further comprises a control valve (7) connected to the pressure valve (4), to the intake manifold (5) in front of the throttle valve (6) and to the intake manifold (5) behind the throttle valve (6), and the control valve (7) is adapted to regulate the opening and closing of the pressure valve. (4).
Patent CZ-308923-B6 (CZ)
Title: Brush section of tunnel washing lines for washing labels from crates
Inventor: SRP DAVID
IPC: B08B9/36
Filed: 2020-07-08
Abstract: The brush section (1) of the tunnel washing lines (0) for labels washing from the crates (3) has a conveyor (2), rinsing with water (4), at least two left side brushes (5) on the left side of the washing space of the brush section (1) and at least two right side brushes (6) on the right side of the washing space of the brush section (1), the left side brushes (5) and the right side brushes (6) are circular and the centring of the left side brushes (5) lie on the left side line (a), which is parallel to the right side line (b) on which the centres of the right side brushes (6) lie, the left side line (a) and the right side line (b) are parallel to the axis (h) of the conveyor feed (2).
Patent SK-285773-B6 (SK)
Title: High axial flow glass coated impeller
Inventor: HEINZMANN MATTHIAS GEORG
IPC: B01F27/91
Filed: 2000-02-08
Abstract: The invention concerns a glass coated high axial flow impeller, including a hub and attached blades. The hub has a centrally located hole, where the hole has a central axis. The impeller has a plurality of angles and edges, all of which have a rounded configuration to permit glassing. The impeller further includes at least two variable pitch blades. Each blade has front and rear surfaces both defined by an inside edge having a leading end and a trailing end, an outside edge having a leading end and a trailing end, a leading edge connecting the leading end of the inside edge to the leading end of the outside edge and a trailing edge that connects the trailing end of the inside edge to the trailing end of the outside edge. The outside edge of each blade is from about 1.5 to 2.5 times the length of the inside edge. The blades are symmetrically attached to the hub at their inside edges; so that, their inside edges are at an angle of from about 45 to about 60 degrees from the central axis of the attached hub and their outside edges are at an angle of from about 50 to about 70 degrees from the central axis of said hub. The angle of the inside edges to the central axis of said hub is from about 6 to about 12 degrees less than the angle of the outside edges to the central axis. The hub and its attached blades are covered by a contiguous coating of glass.
Patent CZ-298482-B6 (CZ)
Title: Examination chair
Inventor: BORUTA IVAN
IPC: A61G13/00
Filed: 1999-11-17
Abstract: The present invention relates to an examination chair intended particularly for gynecological and urological examinations, comprising a base chair part (14) with a seat (22) and a backrest (24), and a support column (12) that has a column head (18), which can be adjusted in height through an adjusting drive (20) for example a spindle drive, on which the base chair part (14) is mounted. The backrest (24) is pivotally mounted on the column head (18) for movement about a horizontal pivot axis (28) and being so pivotable by a drive mechanism (30), the seat (22) being pivotally mounted on the backrest (24) for movement about a second pivot axis (36) parallel to the axis (28) and also connected to the backrest (24) by a four-corner linkage (38) that includes both pivot axes (28,36), a link axis (40) fixed to the seat, and a free link axis (42), the link (46) of the linkage (38) connecting the first pivot axis (28) to the free axis (42) being a first lever arm of a two-armed control lever (48) and cooperating with a stop (54) secured to the column to determine the fundamental position of the seat (22), the second lever arm (50) of the control lever (48) being designed to cooperate with a stop (60) being facedly coupled to the backrest (24).
Patent CZ-302459-B6 (CZ)
Title: Crystal modification 3 of sodium salt of 5-chloro-2-methoxy-N-[2-(4-methoxy-3-methyl-aminothiocarbonylaminosulfonylphenyl)ethyl]benzamide, process for its preparation, the modification for the use as medicament, pharmaceutical composition in which th
Inventor: ENGLERT HEINRICH CHRISTIAN
IPC: A61P43/00
Filed: 2000-04-04
Abstract: In the present invention, there is disclosed a crystal modification 3 of the sodium salt of 5-chloro-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonylphenyl)ethyl)benzamide, having in the X-ray diffraction diagram using Cu K[alpha]1 radiation characteristic X-ray reflections and the preparation of which comprises reacting 5-chloro-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonylphenyl)ethyl)benzamide with a basic sodium compound in a mixture of methanol and ethanol or a mixture of methanol, ethanol, and water and working at temperatures from about -10 degC to about +40degC or it can be prepared from a crystal modification 4, as well as the use thereof for the treatment and prophylaxis of cardiac arrhythmias, ischemic conditions of the heart, further for preventing sudden cardiac death etc. or as an inhibitor of ATP-sensitive potassium channel.
Patent CZ-301901-B6 (CZ)
Title: Pharmaceutical composition comprising lipase inhibitor and process for preparing thereof
Inventor: DE SMIDT PASSCHIER CHRISTIAAN
IPC: A61K47/12
Filed: 2000-09-11
Abstract: In the present invention, there is disclosed a pharmaceutical composition comprising at least one lipase inhibitor, at least one surfactant being selected from the group consisting of vitamin E (polyethylene glycol 1000) succinate (TPGS), poly(oxyethylene) stearates, poly(oxyethylene) alkyl ethers, poly(oxyethylene) castor oils, poly(glycolyzed) glycerides, lecithins and mixtures thereof, and at least one dispersant. The pharmaceutical composition of the present invention is prepared by mixing the individual components and is used for the preparation of medicaments intended for prevention or treatment of obesity.
Patent CZ-302837-B6 (CZ)
Title: Contact plug
Inventor: LAU THORSTEN
IPC: H01R43/24
Filed: 2002-04-19
Abstract: In the present invention, there is disclosed a contact plug having several contact elements, such as pins (2) arranged side by side in an injection-molded housing, wherein said pins are partially sprayed with a plastic shell (3) to a contact segment (1). The contact segments (1) are performed with diametrally projecting supports (8, 9) and with oppositely projecting supports (8, 9) in corner regions (4, 5, 6, 7) wherein the housing is sprayed into the contact segments (1).
Patent EP-1297389-B8 (EP)
Inventor: DUNNILL PETER
IPC: G05B1/00
Filed: 2001-06-26
Granted: 2010-02-03
Abstract: A development tool ( 2 ) includes a plurality of measuring tools ( 71 ) to ( 76 ) and an industrial process simulation device ( 60 ). The simulation device ( 60 ) simulates a whole industrial scale bioprocess in order to obtain acceptable operating parameters for the industrial scale bioprocess. The measuring tools ( 71 ) to ( 76 ) enable various significant properties of the biomaterial to be measured and evaluated using only a small test quantity of the biomaterial.
Patent EP-1704317-B8 (EP)
Title: Procede de regulation et dispositif de regulation pour un actionneur
Inventor: SCHUERZ WILLIBALD
IPC: F02D41/40
Filed: 2005-01-11
Granted: 2008-05-07
Abstract: L'invention concerne un procédé de régulation conçu pour un actionneur (1-4) d'un injecteur d'un système d'injection d'un moteur à combustion interne. Ce procédé comprend les étapes qui consistent : à prédéfinir une valeur prescrite (SOISOLL) pour le début de l'injection ; à déclencher électriquement l'actionneur (1-4) à un moment de déclenchement spécifique (tTRIGGER) à l'aide d'une énergie d'actionnement spécifique (E) ; à détecter une valeur réelle (SOI1IST, SOI2IST, SOI3IST, SOI4IST) au début de l'injection ; à déterminer un écart entre la valeur prescrite et la valeur réelle (?SOI1, ?SOI2, ?SOI3, ?SOI4) au début de l'injection, et ; à réguler l'énergie d'actionnement (E), en fonction de l'écart entre la valeur prescrite et la valeur réelle (?SOI1, ?SOI2, ?SOI3, ?SOI4) au début de l'injection, pour réguler le début de l'injection.