baber/WOPTO huggingface dataset:
Patent NZ-597910-A (NZ)
Title: Coupling device
Inventor: COOTE CLIVE
IPC: A63B9/00
Filed: 2010-06-18
Abstract: 597910 A coupling device (1) for releasably coupling tubes (10, 11) of a pole dancing pole is disclosed. The coupling device (1) comprises a body and a mechanism comprising a first threaded element (5) and a screw member (7) mating with each other. The mechanism is arranged to apply a force to an interior surface of at least one of the tubes (10, 11) by turning the screw member (7) with respect to the first threaded element (5). The mechanism is arranged such that, during operation of the mechanism a screw axis of the threaded element (5) and a screw axis of the screw member (7) remain substantially aligned with each other.
Patent NZ-598441-A (NZ)
Title: Boron-containing small molecules
Inventor: BAKER STEPHEN J
IPC: A61K31/343
Filed: 2006-02-16
Abstract: 598441 Disclosed are 1,3-dihydro-1-hydroxy-2,1-benzoxaborole derivatives as represented by the general formula (I), wherein R1b and R7b are hydrogen, and R11b and R10b are as defined herein; and wherein the compounds are 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 6-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 6-(3-cyanophenoxy)-1,3-dihydro-1-hydroxy-2,2-benzoxaborole, 6-(4-chlorophenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 5-(4-cyanobenzyloxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 5-(2-cyanophenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 5-[4-(N,N-diethylcamamoyl)phenoxy]-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 1,3-dihydro-1-hydroxy-5-[4-(morpholinocarbonyl)phenoxy]-2,1-benzoxaborole, 5-(3,4-dicyanophenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 6-phenylthio-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 6-(4-trifluoromethoxyphenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 6-(4-methoxyphenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 6-(4-methoxyphenyithio)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 5-(3-cyanophenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 5-(4-carboxyphenoxy)-1-hydroxy-2,1-benzoxaborole, and 1-hydroxy-5-[4-(tetrazole-1-yl)phenoxy]-2,1-benzoxaborole. Further disclosed is a pharmaceutical formulation comprising a compound as defined above and a pharmaceutically acceptable excipient, for the treatment of inflammation, and wherein said formulation may be formulated for administration to a site which is skin, nail, hair or skin surrounding the nail or hair.
Patent NZ-600206-A (NZ)
Title: Brassica plants yielding oils with a low total saturated fatty acid content
Inventor: ZHENG HONGGANG
IPC: A01H6/20
Filed: 2010-12-20
Abstract: Discloses a Brassica plant comprising a mutant allele at a fatty acyl-acly-ACP thioesterase A2 (FATA2) locus, wherein said mutant allele results in the production of a FATA2 polypeptide having reduce thioesterase actuvity relative to a corresponding wild-type FATA polypeptide. Further discloses seeds, production of oil and a method for making a Brassica plant.
Patent NZ-600355-A (NZ)
Title: Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
Inventor: RUEGGER COLLEEN
IPC: A61K47/00
Filed: 2008-10-09
Abstract: ABSTRACT - 600355 Discloses herein is a stable blend comprising (i) a compound selected from 2-amino-2-[2-( 4-octylphenyl) ethyl]propane-1,3-diol (FTY720) in free form, a pharmaceutically acceptable salt thereof, FTY720-phosphate, 1-{ 4-[1-( 4-cyclohexyl-3-trifluoromethyl-benzyloxyim i no )-ethyl]-2-ethyl-benzyl} -azetidine-3-carboxylix acid, and (ii) one or more of the following excipients: (a) Fillers selected from lactose monohydrate, lactose anhydrous, maize starch, sorbitol, sucrose, microcrystalline cellulose, dibasic calcium phosphate, maltodextrin, gelatin and/or (b) Binders selected from HPMC, L-HPC, povidone, HPC and/or (c) Disintegrants selected from maize starch, crospovidone, croscarmellose sodium, sodium carboxymethylstarch, pregelatinized starch, calcium silicate and/or (d) Lubricants selected from hydrogenated castor oil, glycerol behenate, magnesium stearate, calcium stearate, zinc stearate, mineral oil, silicone fluid, sodium lauryl sulfate, L- leucine, sodium stearyl fumarate, and/or (e) Flow regulators selected from colloidal silicone dioxide, talc and/or (f) Matrix formers selected from hydroxypropyl methyl cellulose, hydroxypropyl cellulose, methyl cellulose, ethyl cellulose, pullulan, starch, povidone and/or (g) Plastisizers selected from PEG 400, Dibutyl sebacate, sorbitol and/or (h) Flavoring agents selected from menthol, tutti fruit and/or (i) Sweeteners selected from sucralose, sodium saccharine.
Patent NZ-600572-A (NZ)
Title: Mesh infrastructure utilizing alternative communication paths
Inventor: MASON ROBERT T
IPC: H04L12/28
Filed: 2011-01-28
Abstract: Disclosed is a wireless network (112) comprising a control node (116) and a plurality of communication nodes (114) in wireless communication with the control node (116). Each of the communication nodes (114) have a wireless communication path to the control node (116) that is either a direct path or an indirect path through one or more other communication nodes (114) that serve as repeaters. For each communication node (114) in wireless communication with the control node (116), the control node (116) determines an alternative communication path and stores primary communication path information and alternative communication path information. The alternative communication path is determined based on which communication path of a plurality of communication paths has a lowest-level common parent node as a primary communication path.
Patent NZ-602528-A (NZ)
Title: Load bearing construction pile
Inventor: REID STEPHEN JAMES
IPC: E02D27/16
Filed: 2011-02-25
Abstract: 602528 Disclosed is a load bearing construction pile assembly (4) for structural support and the recovery and or storage of heat in the upper level of the ground. The pile assembly (4) comprises a pile (6) and a support manifold (8). The support manifold (8) is located at an upper end (10) of the pile (6). The pile (6) comprises an outer tube, inner tube and vortex manifold located at a lower end portion of the pile (6). When the vortex manifold is in use, fluid is passed downwardly through the inner tube and upwardly through an annular passageway. The annular passageway is defined between the inner and outer tubes. The vortex manifold induces swirling of the fluid so that it enters the annular passageway as a spiral flow.
Patent NZ-603915-A (NZ)
Title: Improvements in and relating to signs
Inventor: ROGERS JASON PAUL
IPC: G09F7/00
Filed: 2012-08-28
Abstract: A closed cell coreboard base for a sign having a display surface formed from a planar sheet of closed cell coreboard, where the base, in use, spans a distance X along an axis for and aft of the plane of the display surface, and wherein the base has a slot, dimensioned to frictionally receive, front and rear planar surfaces of the display surface, and wherein the axis of the slot Y is substantially perpendicular to the for and aft axis, wherein the distance X and effective depth of the slot are both sufficient to maintain the display surface in a substantially vertical orientation.
Patent NZ-604480-A (NZ)
Title: Morpholino pyrimidines and their use in therapy
Inventor: FOOTE KEVIN MICHAEL
IPC: C07D471/04
Filed: 2011-06-09
Abstract: The disclosure relates to pyrimidinyl compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification. The disclosure also provides processes for their preparation, pharmaceutical compositions containing them and their use in therapy. These compounds are suitable for the treatment of cancer or for the prevention or treatment of those tumours which are sensitive to inhibition of ATR kinase.
Patent NZ-619375-A (NZ)
Title: Highly reliable ingestible event markers and methods for using the same
Inventor: ROBERTSON TIMOTHY
IPC: A61B5/07
Filed: 2010-04-27
Abstract: An ingestible event marker comprises a support; a control circuit physically associated with the support to control the ingestible event marker; a first electrochemical material physically associated with the support and electrically coupled to the control circuit; a second electrochemical material electrically coupled to the control circuit and physically associated with the support at a location different from the location of the first material such that the first and second electrochemical materials are electrically isolated from each other and a membrane. The first electrochemical material is dissimilar from the second electrochemical material, and the first and second electrochemical materials are configured to produce an actual dipole having a predefined dipole length. The membrane is physically associated with the support and positioned relative to the first electrochemical material and the second electrochemical material to produce a virtual dipole having a length defined by the membrane. The virtual dipole length is larger than the actual dipole length and he first and the second electrochemical materials are configured to generate a voltage potential to power the control circuit when the first and the second electrochemical materials come into contact with an electrically conductive liquid at a target physiological site. A system comprising: an active agent; and the above described ingestible event marker is further disclosed.
Patent NZ-619379-A (NZ)
Title: Stabilized formulations containing anti-pcsk9 antibodies
Inventor: WALSH SCOTT
IPC: C07K16/40
Filed: 2012-07-27
Abstract: Discloses a liquid pharmaceutical formulation comprising: (a) 50±7.5 mg/mL to 250±37.5 mg/mL of an antibody or antigen-binding fragment thereof that specifically binds human proprotein convertase subtilisin kexin-9 (PCSK9), wherein the antibody comprises a heavy chain complementarity determining region (HCDR) 1 of SEQ ID NO:2, an HCDR2 of SEQ ID NO:3, an HCDR3 of SEQ ID NO:4, a light chain complementarity determining region (LCDR) 1 of SEQ ID NO:6, an LCDR2 of SEQ ID NO:7, and an LCDR3 of SEQ ID NO:8; (b) 10±1.5 mM histidine (pH 6.0±0.3); (c) 0.01±0.0015% w/v polysorbate 20; and (d) 10±1.5% sucrose.
Patent NZ-621969-A (NZ)
Title: Method of producing chocolate
Inventor: PAGGIOS KONSTANTINOS
IPC: A23G1/40
Filed: 2012-09-11
Abstract: The disclosure relates to a method of producing chocolate comprising mixing for 10-120 minutes a composition having a temperature of 35-50 degrees Celsius, the composition comprising chocolate base mass, and one or more surfactants; wherein the composition has a fat content of 22-30 wt% and a water content of at least 1.1 wt% relative to the total mass of the composition. The composition may comprise one or more of hydrated salts, hydrated sugars and hydrated sugar alcohols. The chocolate base mass may comprise milk chocolate, white chocolate or a mixture of milk chocolate and white chocolate. The heat-treatment may be exposing the composition to microwave radiation.
Patent NZ-622717-A (NZ)
Title: New aryl-quinoline derivatives
Inventor: CECCARELLI SIMONA M
IPC: C07D413/04
Filed: 2012-10-29
Abstract: The disclosure relates to aryl-quinoline derivatives having the general formula (I) which are fatty-acid binding protein (FABP) 4 and/or 5 inhibitors, for example dual FABP 4/5 inhibitors, for the treatment or prophylaxis of lipodystrophy, type 2 diabetes, dyslipidemia, atherosclerosis, liver diseases involving inflammation, steatosis and/or fibrosis, such as non-alcoholic fatty liver disease, in particular non-alcoholic steatohepatitis, metabolic syndrome, obesity, chronic inflammatory and autoimmune inflammatory diseases. An example of the disclosed derivatives is 6-chloro-2-cyclopropyl-4-phenyl-quinoline-3-carboxylic acid.
Patent NZ-623581-A (NZ)
Title: Wall structure and method
Inventor: CHAD BAX
IPC: E04B1/82
Filed: 2014-04-08
Abstract: Disclosed are a wall structure for a wall (10) of a building and a method of constructing a wall structure. The disclosure notes that materials used to construct walls which reduce the transmission of noise are often costly and therefore not often adopted. The wall structure comprises a first inner wall member (12); a second inner wall member (26); a first outer wall member (46); a second outer wall member (64); a first enclosed bulkhead (50) and a second enclosed bulkhead (68). The first inner wall member (12) extends between a first level (16) and a second level (14) of the building (2). The second inner wall member (26) extends substantially between the first (16) and second (14) levels. The first outer wall member (46) is connected to the first inner wall member (12) for forming a covering for the first inner wall member (12). The first outer wall member (46) extends in alignment with the first inner wall member (12) to a first distance in the direction between the first level (16) and the second level (14) to form a covered part of the first inner wall member (12) and an uncovered part (48) of the first inner wall member (12). The first outer wall member (46) has a first upper edge spaced from the first level (16). Similarly, the second outer wall member (64) is connected to the second inner wall member (26) to form a covering and extends in alignment with the second inner wall member (26) to a second distance to form a covered part and an uncovered part of the second inner wall member (26). The second outer wall member (64) has a second upper edge spaced from the first level (16). The first enclosed bulkhead (50) is located on a first side of the wall structure. The second enclosed bulkhead (68) is located on a second side of the wall structure. The first bulkhead (50) extends from the first level (16) in a direction towards a first side of the wall structure. The first bulkhead (50) extends from the first level (16) in a direction towards the second level (14) to a distance so as to contact the first outer wall member (46) to cover the uncovered part (48) of the first outer wall member (46). The second bulkhead (68) extends from the first level (16) in a direction towards a second side of the wall structure. The second bulkhead (68) extends from the first level (16) in a direction towards the second level (14) to a distance so as to contact the second outer wall member (64) to cover the uncovered part of the second outer wall member (64).
Patent NZ-624412-A (NZ)
Title: Inductively transferring electric energy to a vehicle using consecutive segments which are operated at the same time
Inventor: WORONOWICZ KONRAD
IPC: H01F38/14
Filed: 2012-11-09
Abstract: Disclosed is a system for inductively transferring electric energy to a vehicle (81) using an electric conductor arrangement for producing an alternating electromagnetic field and for thereby transferring the energy to the vehicle (81). The conductor arrangement comprises a plurality of consecutive segments (T1, T2, T3) extending in the direction of travel of the vehicle (81), which is defined by the track (83) or path of travel. Each segment (T1, T2, T3) is combined with an assigned controller adapted to control the operation of the segment (T1, T2, T3) independently of the other segments (T1, T2, T3). The controllers of at least two consecutive segments (T1, T2, T3), which follow each other in the direction of travel of the vehicle (81), or which follow each other opposite to the direction of travel, are connected to each other and/or to a central controlling device so that the at least two consecutive segments (T1, T2, T3) can be operated at the same time. Each segment (T1, T2, T3) comprises at least three alternating current lines for carrying phases of a multi-phase alternating current in order to produce the alternating electromagnetic field. The consecutive segments (T1, T2, T3) are electrically connected in parallel to each other to a current supply. The alternating current lines of each segment (T1, T2, T3) comprise a plurality of sections which extend transversely to the direction of travel of the vehicle (81). The transversely extending sections of the at least three alternating current lines of each segment (T1, T2, T3) form, if viewed in the direction of travel, a repeating sequence of phases of the alternating current, while the segment (T1, T2, T3) is operated under control of the assigned controller. Each complete repetition of the sequence of phases comprises one transversely extending section of each phase and the order of the phases is the same in each complete repetition. The controllers of the at least two consecutive segments (T1, T2, T3) and/or the central controlling device are/is adapted to operate the at least two consecutive segments (T1, T2, T3) so that the repeating sequence of phases continues from one segment (T2) to the consecutive segment (T3) and the order of the phases is the same in the at least two consecutive segments (T1, T2, T3) and in each transition zone of two of the at least two consecutive segments (T1, T2, T3).
Patent NZ-624976-A (NZ)
Title: Endplate for hot isostatic pressing canister, hot isostatic pressing canister, and hot isostatic pressing method
Inventor: LIPETZKY PETER
IPC: C22C1/04
Filed: 2012-11-12
Abstract: Disclosed is an endplate for a hot isostatic pressing canister for improving the powder filling characteristics of the cylinder without adding additional fill stems. The endplate comprises a central region, and a main region extending radially from the central region and terminating in a corner about a periphery of the endplate. The thickness of the endplate increases along the main region, from the central region to the corner, defining a taper angle. The corner includes an inner surface comprising a radiused portion by which the main region smoothly transitions into the lip. A hot isostatic pressing canister including at least one of the endplates also is disclosed, along with a method of hot isostatic pressing a metallurgical powder using the hot isostatic canister.
Patent NZ-625391-A (NZ)
Title: Human anti-ngf neutralizing antibodies as selective ngf pathway inhibitors
Inventor: TREANOR JAMES J S
IPC: G01N33/53
Filed: 2010-10-08
Abstract: Discloses use of an NGF antibody in the manufacture of a medicament for treating pain that is associated with a condition caused by increased expression of nerve growth factor (NGF) or increased sensitivity to NGF, wherein the antibody is to be administered in a pharmaceutical composition comprising: a pharmaceutically acceptable carrier and the isolated antibody, wherein the antibody comprises a light chain comprising SEQ ID NO: 44 and a heavy chain comprising SEQ ID NO: 40; wherein the NGF antibody is to be administered by subcutaneous injection, wherein the subcutaneous injection comprises multiple subcutaneous injections; wherein the NGF antibody dose is from 3 mg to 30 mg per subcutaneous injection, wherein the sequences are as defined in the complete specification.
Patent NZ-627668-A (NZ)
Title: Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography
Inventor: HICKMAN ROBERT K
IPC: C07K16/24
Filed: 2010-10-20
Abstract: Disclosed is a method for producing a host cell protein-reduced (HCP-reduced) anti-IL-13 antibody, or antigen-binding portion thereof, preparation from a sample mixture comprising an anti-IL-13 antibody, or antigen-binding portion thereof, and at least one HCP, said method comprising: (a) contacting said sample mixture with Protein A affinity chromatography resin, washing said affinity chromatography resin with a buffer comprising 25 mM Tris, 100 mM NaCl, pH 7.2, followed by a buffer comprising 20 mM sodium citrate/citric acid, 0.5 M NaCl, pH 6.0, and then with a buffer comprising 25 mM Tris, 100 mM NaCl, pH 7.2, and collecting an affinity chromatography sample; (b) subjecting said affinity chromatography sample to a reduction in pH thus forming a reduced pH sample, wherein reduced pH sample has a pH of about 3 to about 4; (c) adjusting said reduced pH sample to a pH of about 4.5 to about 8.5 and contacting said adjusted pH sample to an anion exchange material and collecting an ion exchange sample; (d) contacting said ion exchange sample to a hydrophobic interaction chromatography (HIC) material and collecting an HIC sample, wherein said HIC sample comprises said HCP-reduced antibody, or antigen-binding portion thereof, preparation.
Patent NZ-701052-A (NZ)
Title: Automatic injection device
Inventor: JULIAN JOSEPH F
IPC: A61M5/32
Filed: 2007-06-29
Abstract: An automatic injection device has a syringe movable within housing and having a barrel, hollow needle and plug, and has an actuator to push the syringe to inject and then expel fluid, with a window in housing to view fluid before injection
Patent NZ-723880-A (NZ)
Title: Process for preparing quinoline derivatives
Inventor: WILSON JO ANN
IPC: C07D413/12
Filed: 2012-10-22
Abstract: Disclosed herein is a process for preparing Cabozantinib, where the precursor 1-[(4-fluorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is prepared by (e) contacting 1,1 -cyclopropane dicarboxylic acid with thionyl chloride in a polar aprotic solvent; (b) adding 4-fluoroaniline and triethyl amine in a polar aprotic solvent to the mixture of step (e). subsequently this is converted to 1-(-Fluoro-phenylcarbamoyl)-cyclopropanecarbonyl chloride. The intermediate 4-Chloro-6,7-dimethoxy-quinoline is prepared from 6,7-dhnethoxy-quinoline-4-ol, followed by reaction with 4-Aminophenol to give 4-(6,7-Dimethoxy-quinoline-4-yloxy)-phenylamine, which is then reacted with 1-(4-Fluoro-phenylcarbamoyl)-cyclopropanecarbonyl chloride to give N-(4-{ [6,7-bis(methyloxy)quinolin-4-yl]oxy} phenyl)-N’-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Patent NZ-734396-A (NZ)
Title: Tube rack tool
Inventor: TAYLOR LOGAN M
IPC: B01L9/06
Filed: 2016-02-11
Abstract: Tools and methods are provided for removing a plurality of tubes from a rack of tubes. Tube rack tools include a base and/or top piece for receiving the rack of tubes. The base has a support surface for engaging the closed bottom of the plurality of tubes. The support surface can be curved such that the rack of tubes can be rocked about the curves support surface to dislodge the plurality of tubes from the rack. The top piece can be configured to engage the rack such that pressure on the top piece in the direction of the support surface applies a pressure on the rack without applying the pressure to the tubes. The tubes are dislodged from the rack by application of the pressure. Elements of the tube rack tool are also configured for securing the tubes within the rack or caps to the tubes.
Patent NZ-763585-A (NZ)
Title: Methods, kits and apparatus for expanding a population of cells
Inventor: GERMEROTH LOTHAR
IPC: C12N5/078
Filed: 2015-04-16
Abstract: The present invention relates to in vitro-methods of expanding a population of cells such as lymphocytes, comprising contacting a sample comprising a population of cells with a multimerization reagent. The multimerization reagent has reversibly immobilized thereon (bound thereto) a first agent that provides a primary activation signal to the cells and optionally, a second agent that provides a co-stimulatory signal. The invention also provides multimerization reagents, kits, arrangements and an apparatus for expanding cells.
Patent PT-100051-A (PT)
Inventor: CHARTRAIN PIERRE
IPC: F24C7/08
Filed: 1992-01-24
Abstract: The oven includes a cooking enclosure fitted with a movable door (3) hinged to the front face (2) of the said oven and equipped with a fastener (4) comprising a nose (5) and a notch (6). The fastener penetrates into an opening (9) in the front face in order to actuate a movable interlocking element (7). According to the invention, the interlocking element includes a pivoting wheel (20) positioned on a platen (14) fixed to the inner front face of the oven. The said wheel includes a first face (A) comprising two stop contacts (22 and 23), a safety interlock consisting of a locking finger (25) fixed to the second face (B) of the wheel and controlled by a safety pin (24) protruding through a slot (23') transversely to the first face (A) and intended, either to abut with the catch lock (26) of the platen, or to permit rotation of the wheel. Application to all closing devices. 
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