baber/WOPTO huggingface dataset:
Patent DE-69229482-T2 (DE)
Inventor: TSUCHIYA MASAYUKI
IPC: C12N15/13
Filed: 1992-04-24
Granted: 1999-11-18
Abstract: A reconstituted human antibody against a human interleukin 6 receptor (IL-6R), which is composed of: (A) an L chain composed of (1) the C region of a human L chain and (2) the V region of an L chain comprising the framework region (FR) of a human L chain and the complementarity-determining region (CDR) of the L chain of a mouse monoclonal antibody against a human IL-6R, and (B) an H chain composed of (1) the C region of a human H chain and (2) the V region of an H chain comprising the FR of a human H chain and the CDR of the H chain of a mouse monoclonal antibody against a human IL-6R. Since most of the reconstituted human antibody originates in human antibodies and the CDR is lowly antigenic, this antibody is lowly antigenic against human and hence prospective as a therapeutic agent.   <IMAGE>
Patent DE-69230499-T2 (DE)
Inventor: BRADEN MICHAEL
IPC: C08F265/06
Filed: 1992-11-17
Granted: 2000-07-06
Abstract: PCT No. PCT/GB92/02128 Sec. 371 Date Jun. 16, 1994 Sec. 102(e) Date Jun. 16, 1994 PCT Filed Nov. 17, 1992 PCT Pub. No. WO93/09819 PCT Pub. Date May 27, 1993.A curable composition of a monomeric heterocyclic acrylic or methacrylic ester and an acrylate or methacrylate polymer is used to promote tissue repair, especially cartilage repair.
Patent DE-69230747-T2 (DE)
Inventor: TONELLI CLAUDIO
IPC: B01J20/285
Filed: 1992-10-21
Granted: 2000-09-07
Abstract: A process for separating, or enriching, in non-functional, monofunctional and bifunctional species the perfluoropolyoxyalkylenes of formula (I): Z-O-Rf-Y where   Rf =   a perfluoropolyoxyalkylene chain comprising one or more monomeric units of formula <CHEM>   <CHEM>  CFXO (X = F, CF3), and optionally also units (-CF2CF2O-); Z, Y,   like or different from each other, are non-functional groups or functional groups -OH, with at least Z or Y in part of such perfluoropolyoxyalkylenes being or containing an -OH group, which consists in subjecting said perfluoropolyoxyalkylenes to column chromatography using, as eluents, non-polar fluorinated solvents, either alone or in admixture with polar solvents.
Patent DE-69231608-T2 (DE)
Inventor: SOUBRIER FLORENT
IPC: C12Q1/6876
Filed: 1992-06-24
Granted: 2001-06-13
Abstract: PCT No. PCT/FR92/00574 Sec. 371 Date Jan. 24, 1994 Sec. 102(e) Date Jan. 24, 1994 PCT Filed Jun. 24, 1992 PCT Pub. No. WO93/00360 PCT Pub. Date Jan. 7, 1993The invention discloses a method for detecting polymorphism in the angiotensin converting enzyme by means of a chain amplification technique, the aim being to detect whether or not the sequence of nucleotides 1451-1738 of intron 16 is present in the human angiotensin converting enzyme gene.
Patent DE-69233208-T2 (DE)
Inventor: LO SEK
IPC: C07F5/02
Filed: 1992-11-18
Granted: 2004-07-08
Abstract: Novel tetrazolylphenylboronic acids, methods for their preparation and methods for preparing biphenyltetrazole compounds which are angiotensin II receptor antagonists or which are useful intermediates to prepare angiotensin II receptor antagonists. <??>An illustrative biphenyl tetrazole compound is 2-n-butyl-4-chloro-1-Ä2'-(tetrazol-5-yl)-1,1'-biphenyl-4-yl)methylÜ-1H-imidazole-5-methanol, potassium salt.
Patent DE-69233237-T2 (DE)
Inventor: LITOVITZ A
IPC: A61B19/00
Filed: 1992-01-16
Granted: 2004-07-15
Abstract: An arrangement for inhibiting the adverse effect of an ambient time varying field having an electric component of 5 Kv/M or less and/or a magnetic component of 500  mu T or less on a living system. To provide protection, at least one of the characteristic parameters of said field to which the living system is exposed is changed within time intervals of less than 10 seconds. <IMAGE>
Patent DE-69233573-T2 (DE)
Inventor: TURNER LEIGH HOLBROOK
IPC: H04W4/02
Filed: 1992-04-03
Granted: 2006-06-14
Abstract: A system for handling of articles such as baggage or carrier cargo. The system uses the principle of electromagnetic communication in which an interrogator containing a transmitter generates an electromagnetic signal which is transmitted via an interrogator antenna system to an electronic label containing a label receiving antenna. The electronic label is attached to the article as they are processed. The label antenna receives a proportion of the transmitted energy and through a rectifier generates a dc power supply for operation of a reply generation circuit connected either to the label receiving antenna or a separate label reply antenna with the result that an information bearing electromagnetic reply signal is radiated by the label. <IMAGE>
Patent DE-69302502-T2 (DE)
Inventor: GAGNEUX YVES
IPC: B32B37/20
Filed: 1993-02-25
Granted: 1996-11-28
Abstract: Process of manufacturing a ski comprising a principal stage consisting in assembling the following elements in a mould, with heating, said elements including:     - a sliding sole (8),   - metal edges (7),   - at least one lower reinforcement element (9, 10),   - a core (5),   - at least one upper reinforcement element (4),   - a protective and decorative element (11), characterised in that at least one of the reinforcement elements (4, 9, 10, 14) consists of an actual reinforcement layer comprising, on one of its faces, a solid thermoplastic film (15, 16) secured to it in the hot state in a prior operation and having good properties of adhesion to the element with which it is intended to come into contact and to which it is intended to adhere to during the assembly stage. <IMAGE>
Patent DE-69307734-T2 (DE)
Inventor: PASTOR STEPHEN
IPC: C07F9/6574
Filed: 1993-11-22
Granted: 1997-10-09
Abstract: The amorphous solid modification of 2,2',2''-nitrilo[triethyl-tris-(3,3',5,5'-tetra-tert-butyl-1,1'-biphenyl-2,2'-diyl)phosphite] is obtained by melting said compound and rapidly cooling the melt. The amorphous solid is an effective process stabilizer for organic materials, especially polyolefins and particularly polypropylene.
Patent DE-69312051-T2 (DE)
Inventor: YANG TAI-HER
IPC: B60L11/18
Filed: 1993-03-29
Granted: 1997-10-30
Abstract: Since battery is convenient for mounting up, it is widely used for various kinds of appliances, such as electro vehicles, etc. But the kind of storage, or fuel, or thermal, or solar battery has physilcal basic voltage. Generally speaking, we shall choose its voltage and capacity by means of its multiple series and supply it in accordance with the need of load by means of stepped voltage, or control it by serial linear members, or operate it by chopped wave switches. This is an efficient circuit design mainly to provide a multi-output stepped compound voltage, and further to combine with a field intensity control to enable DC motor control circuit to provide continuous linear control among stepped voltages in relation to voltage output or the output by slow increase in speed or slow feedback reduction and further to control the motor by means of series with limited current of solid switch members or constant current output. <IMAGE>
Patent DE-69312176-T2 (DE)
Inventor: CHOU TA-SEN
IPC: C07H13/08
Filed: 1993-06-21
Granted: 1997-12-11
Abstract: A process for providing an alpha-anomer enriched ribofuranosyl sulfonate from a beta-anomer ribofuranosyl sulfonate; comprising treating a beta-anomer ribofuranosyl sulfonate or anomeric mixture thereof with a conjugate anion of a sulfonic acid source at elevated temperatures in an inert solvent.
Patent DE-69316067-T2 (DE)
Inventor: SUZUKI FUMIO
IPC: C07D473/12
Filed: 1993-04-08
Granted: 1998-07-02
Abstract: Disclosed are therapeutic agents for use in the treatment of Parkinson's disease, such agents being xanthine derivatives of the Formula (I) and their pharmaceutical acceptable salts: <CHEM> where R<1>, R<2> and R<3> are each H, C1-C6 alkyl or allyl; and R<4> is cycloalkyl of 3 to 8 carbon atoms, a - (CH2)n-R<5> group where n is an cycloalkyl of 3 to 8 carbon atoms, a - (CH2)n-R<5> group where n is an integer of from 0-4 and R<5> is an aryl group of 6 to 10 carbon atoms or a heterocyclic group, such aryl or heterocyclic group optionally being substituted by up to 3 substituent(s) selected from C1-C6 alkyl, hydroxy, C1-C6 alkoxy, halogen, nitro and amino; or     a <CHEM> group, where Y<1> and Y<2> are each H or CH3 and Z is a substituted or unsubstituted aryl or heterocyclic group as defined under R<5>.
Patent DE-69316691-T2 (DE)
Inventor: NAGOSHI SHIGEYASU
IPC: B41J2/21
Filed: 1993-09-23
Granted: 1998-06-04
Abstract: A recording scan is performed through a relative reciprocation of color recording heads to a recording material. The recording heads are provided with higher recording density than that of input image data, and each comprises a plurality of pixels (2 x 2) for a pixel of input image data. The mixed color of image are recorded in such a manner that their pixels (2 x 2) each are not subjected to superposition of ink of two colors or the more. Thus, it is possible to prevent an occurrence of variations in mixed color, and to record a high quality of color image without increasing a recording time. <IMAGE>
Patent DE-69320676-T2 (DE)
Inventor: FUNAWATARI TAKATSUGU
IPC: G11B33/04
Filed: 1993-03-25
Granted: 1999-03-11
Abstract: A method of packaging a casing (100) for a disc comprises covering an opening and cut outs (5,6) with a sheet shaped member (204) and applying a film in a tubular form so that superposed portions are formed on lateral sides of the casing and heating the superposed portions to fuse the ends of the film. <IMAGE>
Patent DE-69327718-T2 (DE)
Inventor: VIDEAU DIDIER
IPC: C10M169/04
Filed: 1993-07-05
Granted: 2000-08-10
Abstract: PCT No. PCT/FR93/00688 Sec. 371 Date Jan. 6, 1995 Sec. 102(e) Date Jan. 6, 1995 PCT Filed Jul. 5, 1993 PCT Pub. No. WO94/01518 PCT Pub. Date Jan. 20, 1994.An aqueous machining fluid including at least one fatty substance, at least one cyclodextrin and water is disclosed. Also disclosed is a process for making such machining fluid and a process for using the machining fluid to process workpieces, particularly metal pieces, by means of said aqueous machining fluids.
Patent DE-69401511-T2 (DE)
Inventor: LYGUM POUL
IPC: A22C7/00
Filed: 1994-07-13
Granted: 1997-07-24
Abstract: PCT No. PCT/NL94/00165 Sec. 371 Date Nov. 8, 1995 Sec. 102(e) Date Nov. 8, 1995 PCT Filed Jul. 13, 1994 PCT Pub. No. WO95/02337 PCT Pub. Date Jan. 26, 1995A shaping machine for dividing a deformable mass, such as a meat product, into separately shaped portions comprises a stock container, at least two piston-cylinder units for alternately feeding in the mass from the stock container to a shaping plate provided with shaped recesses, and also means for removing the shaped portions from the shaping plate. Valve means for connecting the cylinder alternately to the stock container arc also provided. The cylinders are accommodated next to each other in a housing which has a chamber connecting at one side to the shaping plate and at the other side to the cylinders, while the valve means also operate the connection between chamber and cylinders.
Patent DE-69401618-T2 (DE)
Inventor: ABUSLEME JULIO A
IPC: C08F2/20
Filed: 1994-05-05
Granted: 1997-07-10
Abstract: Fluorinated olefinic monomers, optionally in association with non-fluorinated olefins, are (co)polymerized in aqueous emulsion in the presence of a hydrophilic solvent and of a fluoropolyoxyalkylene having hydrogenated end groups and/or hydrogenated repetitive units. In this way it is possible to obtain high productivities, close to those obtainable using a hydrophilic solvent and a chlorofluorocarbon.
Patent DE-69401755-T2 (DE)
Inventor: VAN BERKEL WILHELMUS
IPC: C07C39/19
Filed: 1994-06-01
Granted: 1997-06-12
Abstract: PCT No. PCT/EP94/01792 Sec. 371 Date Jun. 20, 1996 Sec. 102(e) Date Jun. 20, 1996 PCT Filed Jun. 1, 1994 PCT Pub. No. WO95/02062 PCT Pub. Date Jan. 19, 1995The invention is a process for preparing 4-hydroxy-cinnamyl alcohols by enzymatically oxidizing 4-allyl-phenols using vanillyl alcohol oxidase. The oxidase converts eugenol and chavicol to coniferyl alcohol and coumaryl alcohol, respectively. The vanillyl alcohol oxidase may be obtained from Penicillium simplicissimum.
Patent DE-69404134-T2 (DE)
Inventor: CORNER ANTONIO
IPC: F26B5/04
Filed: 1994-03-21
Granted: 1997-10-30
Abstract: PCT No. PCT/EP94/00876 Sec. 371 Date Aug. 26, 1997 Sec. 102(e) Date Aug. 26, 1997 PCT Filed Mar. 21, 1994 PCT Pub. No. WO94/23255 PCT Pub. Date Oct. 13, 1994The invention relates to a stabilized vacuum apparatus for industrial hide driers with multiple evaporation beds. The apparatus includes a main vacuum source that can be connected to a series of evaporation beds to produce a negative pressure having a preset value in the beds, in steady-state operating conditions. There is a secondary vacuum source which is suitable to produce, in one bed at a time, a negative pressure which is close to the steady-state value, and there is a valve means to selectively connect each bed, which is initially at ambient pressure, first to the secondary vacuum source and then to the main vacuum source, so as to eliminate substantial pressure variations in the remaining beds when each bed is connected to the main vacuum source. The valve means includes, for each bed, a first electric valve on a line for connection to the outside environment, a second electric valve on a line for connection to the secondary vacuum source, and a third electric valve on a line for connection to the main vacuum source. There is also a control unit suitable to control the cyclic sequential opening and closure of the first, second and third electric valves of each bed.
Patent DE-69426773-T2 (DE)
Inventor: NAKAMURA KAZUFUMI
IPC: A01N43/56
Filed: 1994-08-01
Granted: 2001-06-13
Abstract: A pyrazole derivative represented by general formula (I) or a salt thereof, and a herbicide containing the same as the active ingredient, wherein R<1>, R<2>, X<1>, X<2>, X<3>, X<4> and n are each as set forth in claim 1. <CHEM>
Patent DE-69427552-T2 (DE)
Inventor: KASHIWAZAKI AKIO
IPC: C09D11/322
Filed: 1994-03-31
Granted: 2001-10-04
Abstract: An ink is provided which contains a pigment and a dispersing agent in an aqueous medium, and further contains at least one fine particulate white inorganic material selected from fine particulate titanium dioxide, and fine particulate alumina. An ink-jet recording method and an ink-jet recording apparatus are also provided. <IMAGE>   <IMAGE>
Patent DE-69430948-T2 (DE)
Inventor: JOLY ANDRE
IPC: C08L91/00
Filed: 1994-01-24
Granted: 2003-01-16
Abstract: An emulsion containing (a) a hydrocarbon binder including at least 80 % of a hydrocarbon matrix selected from straight-run, deasphalted or oxidized bitumens in a pure, fluidized or fluxed state, and regeneration binders; and (b) at least one natural or synthetic drying or semi-drying oil, or at least one stand oil thereof.
Patent DE-69523390-T2 (DE)
Inventor: STASIK ANTHONY
IPC: B60W10/10
Filed: 1995-07-27
Granted: 2002-05-16
Abstract: A control system and method for a vehicular semi-automatic mechanical transmission system (10) is provided for continuously informing the operator of available ratios and for permitting selection of a desired shift (GRT(2)), which will be immediately implemented, regardless of the previous selection or ongoing shift implementation, of engagement of a previously selected target ratio (GRT(2)). During a shift transient to engage a selected target ratio (GRT(1)), the display will show the maximum available upshifts and downshifts from the target ratio, and shift requests will be interpreted as requests for upshifts and downshifts from the initial target ratio (GRT(1)) into a new target ratio (GRT(2)). <MATH>   <MATH>
Patent DE-69524004-T2 (DE)
Inventor: DOBMEIER LUDWIG
IPC: B62D43/04
Filed: 1995-07-18
Granted: 2002-07-18
Abstract: A winch assembly (400) is provided including a single mounting bracket (410) for mounting the winch assembly directly to a frame (for example beams) of a vehicle having a front and rear. The mounting bracket (410) has a winch mounting area provided therewith, and a tire carrier (455) and cooperative flexible member (128) outlet area spaced from the winch mounting area towards the front of the vehicle. The mounting bracket is adapted to bolt directly to the frame members (for example beams) of a vehicle. The mounting bracket for the winch therefore obviates the need to provide welded or fastened reinforcing plates with the vehicle proximate the locations wherein the winch assembly is to be mounted.
Patent DE-69528287-T2 (DE)
Inventor: CHANDRAKUMAR SAMUEL
IPC: C07D277/34
Filed: 1995-10-10
Granted: 2003-07-31
Abstract: The present invention provides compounds of the formula Ar<1>-Q-Ar<2>-Y-R-Z and pharmaceutically acceptable salts thereof wherein Ar<1> and Ar<2> are optionally substituted aryl moieties, Z is an optionally substituted nitrogen-containing moiety which may be an acyclic, cyclic or bicyclic amine or an optionally substituted monocyclic or bicyclic nitrogen-containing heteroaromatic moiety; Q is a linking group capable of linking two aryl groups; R is an alkylene moiety; Y is a linking moiety capable of linking an aryl group to an alkylene moiety and wherein Z is bonded to R through a nitrogen atom. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of inflammatory diseases which are mediated by LTB4 production, such as proriasis, ulcerative colitis, IBD and asthma.
Patent DE-69530098-T2 (DE)
Inventor: MARTINSEN ORJAN G
IPC: A61B5/05
Filed: 1995-10-09
Granted: 2004-02-19
Abstract: PCT No. PCT/NO95/00184 Sec. 371 Date Apr. 10, 1997 Sec. 102(e) Date Apr. 10, 1997 PCT Filed Oct. 9, 1995 PCT Pub. No. WO96/10951 PCT Pub. Date Apr. 18, 1996In order to measure the moisture content in skin, especially in the keratinous layer (stratum corneum), at least two electrodes are employed, at least one of which electrodes is placed on the skin where moisture has to be measured, the electrodes are supplied with a periodic voltage with a frequency of less than 50 kHz, and the susceptance in the keratinous layer is measured beneath the electrode or electrodes. In an apparatus for measuring the moisture content in skin three electrodes are employed, a periodic voltage being applied to two of these. The susceptance is measured below one of the electrodes, uninfluenced by the other electrodes, the measurement thus being truly monopolar.
Patent DE-69530516-T2 (DE)
Inventor: HIRATA MITSUTERU
IPC: C07D239/69
Filed: 1995-12-19
Granted: 2003-12-24
Abstract: The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: <CHEM> Äwherein R<1> represents a lower alkyl group; each of R<2> and R<3> represents H, alkyl, or alkoxy; each of R<4> and R<5> represents H or alkyl; R<6> represents alkyl, -OR<7>, or -NR<8>R<9>; and n is a number between 0 and 3 inclusive (wherein each of R<7>, R<8>, and R<9> represents H, alkyl, aryl, aralkyl, amino, a heterocyclic ring, etc.)Ü, as well as to a medicine containing the derivative or salt as the active ingredient. The present compounds exhibit strong binding inhibitory activity against endothelin having potent vasoconstrictive effect and cell proliferation effect. Therefore, the compounds are effective as remedies for various diseases including circulatory diseases.
Patent DE-69534599-T2 (DE)
Inventor: SPRINGER J
IPC: A61K35/76
Filed: 1995-07-27
Granted: 2006-07-20
Abstract: The invention provides a two component system for use in association with one another comprising:   (a) a vector capable of expressing an enzyme at the surface of a cell; and (b) a prodrug which can be converted into an active drug by said enzyme, useful in the treatment of tumours.
Patent DE-69600667-T2 (DE)
Inventor: VERRELST WIM
IPC: C07C11/02
Filed: 1996-01-29
Granted: 1999-04-08
Abstract: A molecular sieve comprising a core having deposited thereon a surface layer, wherein the core is a zeolite containing silicon and at least one element selected from gallium and iron and the surface layer has a higher Si:Al ratio than that of the silicon:selected element ratio of the core, provides for lower branching in olefin oligomerization products.
Patent DE-69603242-T2 (DE)
Inventor: CREGUT MICHEL
IPC: B65F1/16
Filed: 1996-11-13
Granted: 2000-01-05
Abstract: The rubbish bin (1) comprises a collection tank (2) and cover (6) which can be displaced between open and closed positions. The cover is hinged (9) to the tank. The bin cover has a resistance for braking (11) during its passage from open to closed positions. This brake comprises a deformable elastic spring (12) fixed to the tank and to the cover. One end of the spring forming a rectilinear part is housed in an opening in the tank and its other end has a horizontally projecting support zone at right angles to an upper peripheral edge (5) of the tank. The spring projecting part is supported on a cover contact surface at a radial distance from the hinge axis (X). The spring is active during cover closing until it is almost closed and is inactive during the rest of cover travel.
Patent DE-69604155-T2 (DE)
Inventor: UPTON ALBERT
IPC: B26B9/00
Filed: 1996-03-28
Granted: 2000-03-09
Abstract: PCT No. PCT/GB96/00752 Sec. 371 Date Jan. 6, 1998 Sec. 102(e) Date Jan. 6, 1998 PCT Filed Mar. 28, 1996 PCT Pub. No. WO96/30173 PCT Pub. Date Oct. 3, 1996A knife blade including a cutting edge formed on a blank. One side of the edge is provided with a coating formed by a particulate material in a matrix. The matrix is softer than the particulate material, and the coating is such that a considerable number of the particulates project from the matrix thereby defining a cutting tip on the blade edge.
Patent DE-69613510-T2 (DE)
Inventor: RIPA GIORGIO
IPC: C01F17/17
Filed: 1996-04-19
Granted: 2001-10-25
Abstract: The invention refers to a novel process for the recovery of gadolinium and its complexing agent from aqueous solutions containing their complexes and/or salts of said complexes.
Patent DE-69613901-T2 (DE)
Inventor: LIEVENS HUGO
IPC: G08B13/24
Filed: 1996-05-20
Granted: 2001-10-31
Abstract: An antipiliferage tag comprising a soft-magnetic thin film (100) for use as an active element in an electronic article surveillance (E.A.S.) system. The film (100) has an easy axis (102) with a particular direction. The tag has been folded along at least one folding line (104) so that the tag comprises at least two layers which at least partially overlap with each other. The folding line (104) forms an oblique angle different from zero with the direction of the easy axis (102) so that the direction of the easy axis (102) in one layer is different from the direction of the easy axis (106) in another layer. In this way an antipiliferage tag which is insensitive to its orientation in a detection gate of an E.A.S. system is obtained.
Patent DE-69625239-T2 (DE)
Inventor: KLUG L
IPC: G01N33/574
Filed: 1996-09-19
Granted: 2003-11-06
Abstract: Diagnostic/prognostic methods are provided for screening for pathologies wherein an alteration in estrogen metabolism is indicative of a pathology or a susceptibility thereto which comprise detecting and/or quantifying directly in tissues and body fluids of mammals abnormal levels of estrone metabolites and their glucuronide conjugates. Particularly preferred methods involve the use of the 16OHE1-, 2OHE1- or 2MeoE1-glucuronide fraction, i.e., the fraction which contains the metabolite and its 3-glucuronide conjugate. Methods of preparing reagents to detect said 16OHE1-, 2OHE1-, and 2MeoE1-glucuronide fraction in tissues and body fluids are disclosed as well as test kits for performing the disclosed assays.
Patent DE-69633386-T2 (DE)
Inventor: STEPHENS ANDREW
IPC: C12Q1/68
Filed: 1996-05-01
Granted: 2005-09-22
Abstract: This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to peripheral blood mononuclear cells (PBMC), fibrin clots and carotid arteries are described.