baber/WOPTO huggingface dataset:
Patent IL-156339-A0 (IL)
Title: Indazolyl-substituted pyrroline compounds as kinase inhibitors
IPC: A61P11/06
Filed: 2001-12-06
Abstract: The present invention is directed to novel indazolyl-substituted pyrroline compounds of Formula (I): useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disorder.
Patent IL-157429-A0 (IL)
Title: Mounting and preparing a gemstone or industrial diamond for the formation of a mark on the surface thereof
IPC: A44C27/00
Filed: 2002-02-18
Abstract: To form a micro mark on the table (7a) of a diamond (7), a holder or dop (11) with the diamond (7) is spun, a photo resist is applied to the table (7a), the resist is baked by heating the base of the dop (11), and the dop (11) is transferred to the table (30) of apparatus for exposing the resist. The resist is exposed using an exposure radiation with a pattern which is a reduced image of a mask (35), working through an objective lens (38). The exposure radiation is projected by a radiation source (31) and can be 350 to 450 nm. In order to locate, orientate and focus the image, the radiation source (31) is arranged to project light in the wavelength range 500 to 550 nm, which does not affect the resist, forming a setting-up image on the table (7a), the setting-up image is viewed in an observation plane (44) through the objective lens (38) and a beam splitter (36). After exposure, the resist is developed and the exposed area of the table (7a) is then milled using a plasma.
Patent IL-164013-A0 (IL)
Title: Food additive
IPC: A23L13/60
Filed: 2004-09-09
Abstract: The invention relates to a food additive comprising carraghenate  tau  and sodium stearyl-2-lactylate (SSL). The inventive food additive, which has emulsifying and/or stabilising properties, can be used in the food industry and in the production of food products. <IMAGE>
Patent IL-173369-A0 (IL)
Title: Pharmaceutical combination of g-csf and plgf useful for blood stem cell
IPC: A61K38/18
Filed: 2006-01-26
Abstract: Combined pharmaceutical preparation containing G-CSF and P1GF as the active substances, are useful in the mobilization of blood stem cells in a patient or subject in need thereof.
Patent IL-174890-A0 (IL)
Title: Optimised micro-organism strains for nadph-consuming biosynthetic pathways
IPC: C12P7/18
Filed: 2006-04-10
Abstract: Strain (A) of microorganism that includes a deletion of at least one of the genes udhA, qor and/or pgi, provided that if (A) is a bacterium at least one of udhA and qor is deleted. Independent claims are also included for the following: (1) method for preparing (A); and (2) method for preparing a molecule of interest (I), the biosynthesis of which involves at least one NADPH-dependent reaction.
Patent IL-175649-A0 (IL)
Title: Novel method of preparing 3-fluorinated quinolines
IPC: C07D215/18
Filed: 2006-05-15
Abstract: Preparation of 3-fluoro-quinolines (I) (optionally substituted in the 5-, 6-, 7- and/or 8-position) involves heating a corresponding quinoline-3-diazonium tetrafluoroborate (II) in an inert organic solvent. Preparation of 3-fluoro-quinolines of formula (I) involves heating a quinoline-3-diazonium tetrafluoroborate of formula (II) in an inert organic solvent. [Image] R 1 - R 4H or F; linear, branched or cyclic alkyl (optionally substituted by 1-3 F, by OR 5 or by NR'R''); OR 6, NR' 1R'' 1 or COOR a; or phenyl or heteroaryl, both optionally substituted by one or more of the substituents given above or below; R 5H, alkyl or hydroxy-protecting group; R', R'' : H, alkyl or amino-protecting group; R 6H, phenol protecting group or alkyl (optionally substituted by 1-3 F, by OR 5 or by NR'R''); R' 1, R'' 1as for R', R''; or alkyl substituted by 1-3 F, by OR 5 or by NR'R''; and R aH, alkyl or carboxy-protecting group. An independent claim is included for (II) as new compounds.
Patent IL-178435-A0 (IL)
Title: Beta-carbolines useful for treating inflammatory disease
IPC: A61P35/00
Filed: 2006-10-04
Abstract: This invention provides beta-carboline compounds of formula  III-A-aa:    
wherein Q, G, R 1 , R 2 , R 3 , and R 6b  are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.
Patent IL-205789-A0 (IL)
Title: A rotary electric machine and the method for assembling it
Filed: 2010-05-16
Abstract: An electric machine (1) comprises; a casing; a stator (3) fixed to the casing and including at least one electrical winding (5); a rotor (4) housed in the casing and rotatably connected to the latter; an electronic circuit (8) for powering the winding (5) at least partly housed in the casing; a cover (2a) for closing the casing to form with the latter a sealed enclosure; a terminal strip (9), accessible from outside the sealed enclosure, for controlling and powering the electronic circuit (8); a heat sink, embodied by the cover (2a), for absorbing the heat produced, in particular, by the electronic circuit (8). The machine (1) also comprises elastic elements (12) operating between the stator (3) and the electronic circuit (8) in such a way as to press the electronic circuit (8) against the heat sink.
Patent RO-126272-A0 (RO)
Title: Set of elements and medical device meant to slow down tissue resorption
Inventor: VLĂDILĂ BOGDAN CONSTANTIN
IPC: A61C8/00
Filed: 2010-10-25
Abstract: The invention relates to a set of elements and medical devices meant to slow down tissue resorption in patients in which implant-prosthetic rehabilitation of teeth has been performed. According to the invention, the set includes a dental implant comprising an upper end provided with a central rod (1), made of titanium alloys, at a lower end of said rod (1) there being placed a self-threading leading tip (2) provided with a single or multiple-thread cutting screw (a1) and some cutting teeth (a2), a central jacket (3) preferably made of zirconium oxide which envelopes the rod (1) at a certain distance, so that a small empty space (a4) can exist or not between the jacket (3) and the rod (1), wherein a composition as powder or a tubular piece (4) to accelerate osseointegration is introduced, and a prosthetic blunt (5) placed within a recess (b3) of the upper end of the rod (1) on which a dental crown is made, as well as a composition for accelerating implant osseointegration, made of some substances normalizing the exchanges at the level of the cellular membrane and regulating the enzyme exchange, various implant elements and medical devices to be made of and with said composition.
Patent RO-132850-A0 (RO)
Title: Topical multi-particulate release systems based on bio-polymers with controlled release of an anti-inflammatory medicament and process for preparing the same
Inventor: GHICA MIHAELA VIOLETA
IPC: A61K47/18
Filed: 2018-05-31
Abstract: The invention relates to a multi-particulate system for controlled release of an anti-inflammatory medicament for treating burns of medium severity and to a process for preparing the same. According to the invention, the system consists, in gravimetric percentage related to 100 g of collagen gel, of a polymeric support consisting of a mixture of fibrillar collagen of type I having a content of 0.8...1.2% collagen as dry matter, up to 0.6% flufenamic acid and up to 1.2% dextran, up to 1.2% a reticulation agent of glutaraldehyde type, as well as 15...30% microcapsules comprising 2.50...7.50% gelatin, 0.25...0.75% soda carboxymethylcellulose, 1.60...2.40% flufenamic acid and 0.50...1.50% sodium alginate. The claimed process consists in previously mixing the collagen gel with the flufenamic acid solution, after which dextran is added, the pH is adjusted to 7.4 with sodium hydroxide solution 1 M and distilled water is added up to a final gel content of 0.8...1.2% collagen as dry matter, wherein 15...30% microcapsules are immersed and glutaraldehyde is added as solution with a concentration of 0.2...0.3% in distilled water, the hydrogel resulted being left for ageing at 4°C for 24 h and then it is lyophilised for 48 h, resulting in a multi-particulate system with flufenamic acid in free form and encapsulated, and in encapsulated form, respectively, with bi-phase controlled release of the medicament during 48 h.
Patent RO-134312-A0 (RO)
Title: Powering an electric locomotive of 5100 kw from a power supply wagon equipped with storage batteries for running on non-electrified railway lines
Inventor: TRANDAFIR ALEXANDRU
IPC: B60L58/10
Filed: 2019-10-15
Abstract: The invention relates to a power supply wagon equipped with storage batteries for powering an electric locomotive on non-electrified railway line sections. According to the invention, the power supply wagon is coupled to the electric locomotive of the train and comprises a set of storage battery blocks (BBA), capable of storing and delivering power to the locomotive, a single-phase 50 Hz step-down transformer (TRI) from 25kV to 0.4 kV, which supplies a high power charging supply source (SINC), a device (DMBat) for managing the charge and discharge of storage battery blocks which is provided with an air-conditioning installation for forcedly cooling the blocks, a high power converter included into the device (DMBat) which ensures the conversion of the DC current delivered by the storage battery blocks into a single-phase AC current, some flexible cables with high voltage connection plugs (PFr) at both ends of the power supply wagon.
Patent AP-2002002546-A0 (AP)
Title: Iron chelator delivery system.
Inventor: GWATHMEY JUDITH K
IPC: A61K9/127
Filed: 2000-12-29
Abstract: An iron chelator delivery system is disclosed. The system comprises iron chelator and a lipid carrier,e.g., a liposome. Methods for preparing and administering the iron chelator delivery system are also provided
Patent ZM-8085-A1 (ZM)
Title: A process for separating arsenic from acid solutions
IPC: C22B30/04
Filed: 1985-10-25
Abstract: The process for separating arsenic from acid solutions containing it along with other metals comprises contacting the acid acqueous solution with an organic solvent insoluble in water, having the general formula C6Rn(OH)mH6-(m+n), which extracts the arsenic, the arsenic being in turn stripped from the organic solvent by a countersolvent. Preferably, the organic exctractant is a mono- or di-alkylderivative of pyrocatechol or pyrogallic acid.
Patent IE-910200-A1 (IE)
Title: Triazolopyridines herbicides
IPC: C07D401/12
Filed: 1991-01-21
Abstract: Compounds usable as herbicides and having the formula (I)  in which: * X, Y and Z represent a hydrogen atom or a halogen atom or an alkyl or haloalkyl or alkoxy group, one at least of the radicals X, Y or Z having a meaning other than the hydrogen atom, * Ar represents a phenyl group, optionally mono- or polysubstituted by a lower alkyl or lower alkoxy or lower alkylthio or phenyl or phenoxy group or a halogen atom, or a heterocycle Het, * Het represents a 5- or 6-membered heterocyclic ring containing one or more heteroatom(s) such as sulphur, nitrogen or oxygen, this heterocyclic ring being optionally mono- or polysubstituted by a lower alkyl or lower alkoxy or lower alkylthio group or a halogen atom. The herbicide compositions containing the products of formula (I) and the weeding processes using the compounds of formula (I) or the compositions containing them.
Patent MA-19650-A1 (MA)
IPC: C07D311/30
Filed: 1982-11-24
Abstract: The invention concerns [oxo-4-4H-[1]-benzopyran-8-yl]-alcanoic acids and their derivatives, their manufacture, represented by the formula. <IMAGE>   where AR is hydrogen, a phenyl radical which may or may not be substituted thenyl, furyl, naphthyl, a lower alkyl, cycloalkyl, aralkyl radical; B is a linear or branched lower alkyl radical, either saturated or ethylinically unsaturated; R1 is hydrogen or a phenyl radical; X is hydrogen or a lower alkyl or alkoxy radical and n=1, as well as salts, esters, aminoesters and amides. Compounds and their derivatives may be used as medicines, in particular in the control of tumors.
Patent MA-19892-A1 (MA)
IPC: A61K31/325
Filed: 1983-09-03
Abstract: New benzenesulfonic esters of the formula I    <IMAGE>  I  and a process for their preparation are described. The new compounds are active against helminths and can thus be used as agents to counter worms in humans and animals.
Patent MA-28057-A1 (MA)
Title: Preparation cerealiere complete, naturelle et dietetique a vertus therapeutiques
Inventor: IBRAHIMI ILHAM
IPC: A23L33/00
Filed: 2005-01-19
Abstract: La présente invention consiste en une préparation céréalière complète, naturelle et diététique, à base d'une mouture grossière de plusieurs céréales complètes et d'autres graines à vertus thérapeutiques, pouvant constituer un repas ou compléter une alimentation mal équilibrée, sans aucun danger pour la santé.
Patent MA-28103-A1 (MA)
Title: Procede pour construire une fondation sur pilotis
Inventor: ZAGO ROBERTO
Filed: 2006-04-21
Abstract: L'invention co ncerne un procédé pour construire des fondations sur pilotis, comprenant une structure de fondation (1) construite sur le sol (2), cette dernière comprenant au moins un trou traversant (4), et un élément connecteur (5) fixé à la structure de fondation (1), adjacent au trou (4), et présentant au moins une partie (7) faisant saillie en avant. Les fondations sur pilotis comprennent également un pilotis (3) inséré dans le trou (4), et de nombreuses poussées sont appliquées de manière statique sur le pilotis (3), ce qui permet de guider le pilotis (3) dans le sol (2), au moyen d'un dispositif de poussée (21), situé au-dessus du pilotis (3), ce dernier coopérant avec une extrémité du pilotis (3), et étant relié à la partie faisant saillie (7) de l'élément de liaison (5), qui, lors de l'enfoncement du pilotis, agit comme un élément de réaction pour le dispositif de poussée (21).
Patent MA-20150472-A1 (MA)
Inventor: CHERAH YAHIA
IPC: A61K36/00
Filed: 2014-05-08
Abstract: يقدم هذا الإختراع تركيب للمستخلص مائي إنطلاقا من خليط ل 6 نباتات : الكمون ، ضرم ضيق الأوراق، إكليل الجبل، اليانسون، الشمرة الشائعة للإستعمال كدواء مهدىء للإظطرابات العقلية و الأعراض المرتبطة بها ، فحسب براءة هذا الإختراع، فالدواء يمتاز بنشاطه المهدىء ويسمح هذا الخليط بالرفع من فعالية gaba ( مستقبلات متصلة بحامل أيون الكلور) الذي يتدخل على مستوى الناقل العصبي بواسطة جملة من التفاعلات التفارغية، و تتمثل الوظيفة الرئيسية لل gaba في كبح الأنظمة الأحادية الأمين الأخرى مما يمكن من تفسير المفعول المهدىئ لهذه المحرضات
Patent MA-37506-A1 (MA)
Title: Utilisations thérapeutiques de protéines de facteur de croissance des fibroblastes 21
Inventor: MA YANFEI LINDA
IPC: A61P19/08
Filed: 2013-05-09
Abstract: La présente invention concerne des utilisations thérapeutiques de protéines de facteur de croissance des fibroblastes 21 (fgf21) humain.
Patent MA-43293-A1 (MA)
Title: Fermeture pour des recipients
Inventor: BERROA GARCIA JAVIER
IPC: B65D47/08
Filed: 2016-03-04
Abstract: La présente invention concerne une fermeture (1) pour des récipients qui comprend un corps cylindrique formé par la liaison articulées de deux éléments superposés, un élément inférieur (2) pourvu de moyens d'accrochage pour être retenus sur le col (20) du récipient, et un élément supérieur (3) pourvu d'une base supérieure (5) reliée à une paroi périmétrique (7), laquelle paroi périmétrique (7) comporte un rebord (9) qui permet l'ouverture de la fermeture (1), ledit rebord (9) comprenant une ailette (10) disposée de manière transversale à celui-ci et alignée sur une rainure (4) complémentaire prévue sur le bord supérieur de l'élément inférieur (2), ladite ailette (10) comprenant sur une surface intérieure un cordon (11) disposé de manière transversale à l'axe axial de la fermeture (1) pour effectuer l'accrochage de l'élément supérieur (3) au col (20) du récipient.
Patent MA-55180-A1 (MA)
Title: Méthode de détection des nids-de-poule sur la route
Inventor: TAHIRI MOHAMMED
IPC: G01B21/30
Filed: 2021-12-13
Abstract: Méthode de détection des nids-de-poule sur la route en crowdsourcing basée sur des capteurs de véhicule notamment de position gps et d’accélération comprenant les étapes de détection en temps réel d’accélération horizontale et verticale du véhicule et partager ces informations via le cloud afin de confirmer les emplacements des cavités de chaussé en analysant les différentes entrées des utilisateurs des véhicules équipés par le système d’identification.
Patent UY-23867-A1 (UY)
Title: Procedimiento para la preparacion de derivados del acido acetico
Inventor: HADVARY PAUL
IPC: C07D211/34
Filed: 1994-12-02
Abstract: La presente invención se refiere a nuevos derivados de ácido acético, a un procedimiento para su preparación y preparados farmacéuticos que contienen estos compuestos que pueden utilizarse especialmente para el tratamiento o profilaxis de enfermedades que están causadas por la ligazón de proteínas adhesivas a plaquetas sanguíneas y por la agregación de plaquetas sanguíneas y adhesión de célula - célula; especialmente para tratamiento de trombos de plaquetas sanguíneas, trombosis, ataque, infarto cardíaco, inflamación, arteriosclerosis u osteoporosis, o como antitumorales o para sanar heridas. En particular, el invento se refiere a derivados de ácido acético de fórmula (I), en donde: L es un grupo de la fórmula (L1) a (L5) (ver figura 2), en donde puede estar también presente como una oxima un grupo carbonilo presente en el grupo L y/o entre los grupos L y M que no esté enlazado en la forma de una amida; M es 1,4-piperidinileno enlazado vía el átomo de N al grupo ceto ó 1,4-fenileno opcionalmente sustituido; Q es O, CH2, NH, acilo-N ó alquilo inferior OC(O)N; T es NH2, NH-alquilo inferior, NH-alquilo inferior (COOH o COO-alquilo inferior), alcoxilo inferior o alqueniloxilo inferior sustituido. Se preparan disociando grupos protectores en los compuestos protegidos correspondientes o convirtiendo el grupo ciano en el grupo amidino en nitrilos correspondientes. Por ejemplo: (S)-4-(2-(4-(imino-2-(metoxi-etoxicarbonilamino)-metil)-benzoil-amino)-propionil)-fenoxiacetato de etilo.
Patent UY-24484-A1 (UY)
Title: Redes de telefonia celular, en particular criterio para reselección de estación movil de un canal de control o piloto en un sistema telefónico celular de acceso múltiple por división de tiempo digital (tdma) o acceso múltiple de división de código (cdma), respectivamente.
Inventor: LUPIEN FRANCIS
IPC: H04W60/04
Filed: 1997-03-07
Abstract: En una red telefónica celular TDMA o CDMA que incluye una pluralidad de áreas de registración y en los casos de reselección de celda por la estación móvil entre una celda ubicada en una primera área de registración y una celda ubicada en una segunda área de registración, la estación móvil efectúa mediciones de intensidad de señal de canal de control o piloto tomando en cuenta una histéresis de reselección convencional y una adicional de registración. La reselección es llevada a cabo por la estación móvil cuando la intensidad de señal medida en el canal de control o piloto con respecto a la celda de la segunda área de registración excede la intensidad de señal de canal de control o piloto medida con respecto a la celda de la primera área de registración en la suma total de la histéresis de reselección y de la de registración. Lo antedicho vuelve mas difícil obtener una reselección de celda en el área de interregistración con el beneficio de minimizar la posibilidad de incurrir en un consumo innecesario de recursos valiosos, internase inalámbrica celular y de sistema debido al hecho que la estación móvil se desplaza alternativamente entre las dos áreas de registración.
Patent UY-24608-A1 (UY)
Inventor: DR CARLO FARINA
IPC: A61K31/40
Filed: 1997-07-07
Abstract: A compound of formula (I): or a salt thereof, or a solvate thereof, wherein Ra represents a group R<SUB>5 </SUB>which is hydrogen, alkyl or optionally substituted aryl and Rb represents a moiety of formula (a): wherein X represents a hydroxy or an alkoxy group wherein the alkyl group may be substitued or unsubstituted or X represents a group NR<SUB>s</SUB>R<SUB>t </SUB>wherein R<SUB>s </SUB>and R<SUB>t </SUB>each independently represent hydrogen, alkyl, substituted alkyl, optionally substituted alkenyl, optionally substituted aryl, optionally substituted arylalkyl, an optionally substituted heterocyclic group or an optionally substituted heterocyclylalkyl group, or R<SUB>s </SUB>and R<SUB>t </SUB>together with the nitrogen to which they are attached form a heterocyclic group; R<SUB>1 </SUB>represents an alkyl or a substituted or unsubstituted aryl group; and R<SUB>2</SUB>, R<SUB>3 </SUB>and R<SUB>4 </SUB>each independently represent hydrogen, alkyl, aryl or substituted aryl; R<SUB>6 </SUB>and R<SUB>7 </SUB>each independently represent hydrogen, hydroxy, amino, alkoxy, optionally substituted aryloxy, optionally substituted benzyloxy, alkylamino, dialkylamino, halo, trifluoromethyl, trifluoromethoxy, nitro, alkyl, carboxy, carbalkoxy, carbamoyl, alkylcarbamoyl, or R<SUB>6 </SUB>and R<SUB>7 </SUB>together represent methylenedioxy, carbonyldioxy or carbonyldiamino; and R<SUB>8 </SUB>represents hydrogen, hydroxy, alkynoyl, alkyl, aminoalkyl, hydroxyalkyl, carboxyalky, carbalkoxyalkyl, carbamoyl or aminosulphonyl; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
Patent UY-26776-A1 (UY)
Title: Inhibidores de 3-hidroxi-3-metilglutaril-coenzima a reductasa y métodos.
Inventor: ROBL JEFFREY A
IPC: A61P3/06
Filed: 2001-06-15
Abstract: Se proporcionan compuestos de la siguiente estructura que son inhibidores de HMG CoA reductasa y por lo tanto son activos para inhibir la biosíntesis de colesterol, modular los lípidos en suero sanguíneo, por ejemplo, disminuir el colesterol LDL o incrementar el colesterol HDL, y tratar la hiperlidemia, dislipidemia, hipertrigliceridemia y aterosclerosis así como enfermedades de alzheimer y osteoporosis; y sus sales farmacéuticamente aceptables de los mismos.
Patent UY-30912-A1 (UY)
Title: Derivados de 4-pirazol amidas conteniendo carboxi, sales farmacéuticamente aceptables de los mismo, composiciones farmacéuticas conteniéndolos, procesos de preparacion y uso.
Inventor: STOCKER ANDREW
IPC: A61K31/415
Filed: 2008-02-12
Abstract: Se describe un compuesto de formula (I): y sales farmacéuticamente aceptables del mismo en donde los grupos variables se definen en la presente; su uso en la inhibicion de la 11BHSD1, procesos para su elaboracion y composiciones farmacéiticas que los comprenden.
Patent UY-31125-A1 (UY)
Title: Formas amorfas estabilizadas de mesilato de imatinib
Inventor: LKSHMAN PARTHIBAN
IPC: A61K31/495
Filed: 2008-06-06
Abstract: La invención se refiere a la forma amorfa estabilizada de la sal de adición de ácido metansulfónico de 4-(4-metilpiperazin-1-ilmetil)-N-[4-metil-3-(4-(piridin-3-il)-pirimidin-2-ilamino-)-fenil]-benzamida, composiciones farmacéuticas tales como cápsulas o tabletas que contienen esta forma, el uso de dicha forma en métodos de diagnóstico o, preferiblemente, para el tratamiento terapéutico de animales de sangre caliente, especialmente seres humanos, y al uso de principio de formulación estabilizando la forma amorfa de mesilato de lmatinib como un intermediario para la preparación de composiciones farmacéuticas.