baber/WOPTO huggingface dataset:
Patent DE-69729455-T2 (DE)
Inventor: STEINMAN M
IPC: A61K38/00
Filed: 1997-02-10
Granted: 2005-06-30
Abstract: We describe an improved method for generating sizable numbers of mature dendritic cells from nonproliferating progenitors in human blood. The first step or "priming" phase is a culture of T cell depleted mononuclear cells in medium supplemented with GM-CSF and IL-4 to produce immature dendritic cells. The second step or "differentiation" phase requires the exposure to dendritic cell maturation factor such as monocyte conditioned medium. Using this two-step approach, substantial yields are obtained. The dendritic cells derive from this method have all the features of mature cells. They include a stellate cell shape, nonadherence to plastic, and very strong T cell stimulatory activity. The mature dendritic cells produced according to this invention are useful for activating T cells.
Patent DE-69736432-T2 (DE)
Inventor: TORMO MAR
IPC: A61K31/70
Filed: 1997-10-03
Granted: 2007-03-01
Abstract: The present invention provides novel compositions and methods for use in the treatment of Bcl-2-associated diseases like cancer, specifically, in the treatment of follicular lymphoma (FL). The compositions contain antisense oligonucleotides that hybridize to Bcl-2 nucleic acids, the gene products of which are known to interact with the tumorigenic protein Bcl-2. Used alone, or in conjunction with other antisense oligonucleotides, these compositions inhibit the proliferation of FL cancer cells.
Patent DE-69800185-T2 (DE)
Inventor: PHILIPPE MICHEL
IPC: A61K8/00
Filed: 1998-04-16
Granted: 2000-10-26
Abstract: Salicylic acid salts of formula (I) are new. AR<-> S<2+> AR<-> (I). S<2+> = divalent inorganic cation; AR<-> = group of formula (II); and R5 = 3-15C optionally unsaturated aliphatic group.
Patent DE-69807491-T2 (DE)
Inventor: WHEELER ALFRED
IPC: C09D7/00
Filed: 1998-07-21
Granted: 2003-04-03
Abstract: A method for coating the surface of a substrate and a surface coating made according to the method Involves contacting the surface with a dispersion of a film forming polymer containing droplets of a suspended biliquid foam or emulsion. Then the dispersion is allowed to dry so as to coat the surface with a coating comprising the droplets trapped within a film of the polymer.
Patent DE-69811056-T2 (DE)
Inventor: DE PAOLI MARTIAL
IPC: B60J10/02
Filed: 1998-11-17
Granted: 2004-01-22
Abstract: The invention relates to a system for fitting a window into a bay, especially a window of a transport vehicle; the window is rapidly removable, especially to allow the evacuation of passengers in a vehicle. The window (1) is equipped, by bonding, with a frame (2), especially a metal frame, which itself is fixed to the body opening (3) by discrete mechanical fasteners (6). The latter are locked by systems which, for example, are unlocked from the inside of the vehicle. In one embodiment, the frame (16) is made of an elastomer and it has projections (17) on which locking members (18) bear.
Patent DE-69827810-T2 (DE)
Inventor: MCGREGOR DUNCAN
IPC: C12Q1/68
Filed: 1998-09-02
Granted: 2005-11-10
Abstract: There is described a method of isolating nucleotide sequences encoding target peptides from DNA libraries using DNA binding proteins to link the peptide to the sequence which encodes it. DNA libraries are prepared from cells encoding the protein of interest, or from synthetic DNA, and inserted into, or adjacent to, a DNA binding protein in an expression vector to create a chimeric fusion protein. Incorporation of the vector DNA into a carrier package, during expression of the chimeric fusion protein, results in the production of a peptide display carrier package (PDCP) displaying the DNA-bound fusion protein on the external surface of the carrier package. Employment of affinity purification techniques results in the PDCP particles containing sequences encoding the desired peptide to be selected and the desired nucleotide sequences obtained therefrom.
Patent DE-69833557-T2 (DE)
Inventor: BKAILY GHASSAN
IPC: C07J71/00
Filed: 1998-09-28
Granted: 2006-10-05
Abstract: The present invention relates to Ca<2+> channel blockers and more particularly to the R-type Ca<2+> channel blockers. More specifically, the invention relates to Ca<2+> channel blockers activity of Mandevilla velutina and Mandevilla illustris. The present invention further concerns saponin-like compounds isolated from Mandevilla species. The present invention also relates to the treatment of several pathologies that involve the nifedipine-insensitive but isradipine sensitive steady-state R-type Ca<2+> channel and the use of steady-state R-type Ca<2+> channel blockers in the treatment of these pathologies.
Patent DE-69906277-T2 (DE)
Inventor: CANDUSSO BRUNO
IPC: E06B3/263
Filed: 1999-05-18
Granted: 2003-12-18
Abstract: Profile for window and door frames which is formed by an outer metal profile (1, 2), a plastic profile (3, 4), a resin layer (5) and an inner wood fillet (6, 7). The plastic profile (3, 4) is coupled to the metal profile (1, 2) thanks to two plastic wings (8, 9) on the elastic profile engaged in grooves on the metal profile. The plastic profile (3, 4) is engaged to the wood fillet (6, 7) by the resin layer (5) which fills a channel formed by spacing the metal profile apart from the plastic profile by an arm between the two profiles.
Patent DE-69907890-T2 (DE)
Inventor: MCMILLIN K
IPC: G05D16/20
Filed: 1999-03-30
Granted: 2004-02-19
Abstract: A method and apparatus is disclosed for controlling the pressure of a reaction chamber (106) in wafer processing equipment. The disclosed apparatus and method uses a ballast port (150b) for inserting gas into the evacuation system, thereby controlling the pressure in the reaction chamber. The disclosed apparatus and method further uses estimation curves to estimate the desired position of a controlled gate valve (124) which is located between the reaction chamber and turbo pump (126). The disclosed apparatus and method achieves a set point pressure by prepositioning a throttle valve followed by repositioning the throttle valve based on the difference between a measure pressure and the set point pressure using proportional and integral control, wherein enablement of integral control is delayed for a pre-specified period.
Patent DE-69912338-T2 (DE)
Inventor: DUVALL TOD CHARLES
IPC: C08K3/16
Filed: 1999-03-25
Granted: 2004-05-06
Abstract: Flexible, semi-rigid, and rigid vinyl chloride polymer compositions comprising a latent mercaptan-containing heat stabilizer are substantially free from the offensive odour typically associated with mercaptans and are protected during processing by the degradation products of the latent (i.e., blocked) mercaptan which include a free mercaptan. The free mercaptan thus released enhances the activity of metallic-based heat stabilizers such as zinc carboxylates and organotin carboxylates and mercaptides in the polymer composition. Other products of the degradation are believed to include carbocations of the blocking moiety which are stabilized by a molecular structure in which the electron deficiency is shared by several groups. The latent mercaptan is selected from a 2-S-(tetrahydropyranyl)-thioalkanol, a carboxylic acid ester thereof, a 2-S-(tetrahydropyranyl)-thioglycolic acid, and an ester thereof.
Patent DE-69917026-T2 (DE)
Inventor: CROZET YVES
IPC: A61F2/00
Filed: 1999-06-22
Granted: 2004-10-28
Abstract: The intersomatic spine implant comprises a body, at least one anchoring element movable relative to the body to project from a contact face of the body making contact with a vertebra, and at least one cam slidable relative to the body and suitable for displacing the anchoring element relative to the body by the effect of a ramp engaging the anchoring element. The cam and the anchoring element are arranged so that the cam moves the anchoring element in two opposite displacement directions.
Patent DE-69922261-T2 (DE)
Inventor: HARDY BRITTA
IPC: G01N33/569
Filed: 1999-09-30
Granted: 2005-12-01
Abstract: The invention concerns novel DNA and amino acid sequences of monoclonal antibodies (mAbs) raised against lymphoblastoid cells and peptides to which the mAbs bind to. The invention also concerns diagnostic assays using said antibodies or peptides for detecting individuals with a high probability of having a malignant disease and, at times, for detecting an individual having a specific malignant disease. The invention further concerns pharmaceutical compositions comprising the mAbs or peptides of the invention for use in the treatment of various malignant diseases as well as methods for the treatment of malignant diseases using the mAbs or peptides of the invention.
Patent DE-69928280-T2 (DE)
Inventor: ZUPANICK A
IPC: E21B47/09
Filed: 1999-11-19
Granted: 2006-08-10
Abstract: Improved method and system subterranean deposits from the surface that substantially eliminates or reduces the disadvantages and problems associated with previous systems and methods. In particular, the present invention provides an articulated well with a drainage pattern that intersects a horizontal cavity well. The drainage patterns provide access to a large subterranean area from the surface while the vertical cavity well allows entrained water, hydrocarbons, and other deposits to be efficiently removed and/or produced.
Patent DE-69930554-T2 (DE)
Inventor: MEIRZION TAL
IPC: H04B7/185
Filed: 1999-10-28
Granted: 2007-02-01
Abstract: A VSAT terminal including an antenna, a microwave power amplifier, a microwave low noise amplifier, a transmitter coupled via the microwave power amplifier to the antenna, a receiver coupled via the microwave low noise amplifier to the antenna, a user VSAT interface, and a controller in communication with the user VSAT interface and in electrical connection with the microwave power amplifier and the microwave low noise amplifier for supplying power thereto, the controller being operative to provide a less-than-full electrical power supply to either of the amplifiers in the absence of a communication session and operative to provide a full electrical power supply to either of the amplifiers in the presence of a communication session.
Patent DE-69933897-T2 (DE)
Inventor: KANEKO TAKUSHI
IPC: A61P31/04
Filed: 1999-11-12
Granted: 2007-03-15
Abstract: This invention relates to compounds of the formula 1and to pharmaceutically acceptable salts and solvates thereof wherein X<1>, X<2>, R<2>, R<15>, R<16 >and R<6 >are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
Patent HU-E027826-T2 (HU)
Title: Antibodies against a proliferating inducing ligand (april)
Inventor: MEDEMA JAN PAUL
IPC: C07K16/28
Filed: 2010-02-23
Abstract: The present invention relates to a binding compound which binds to human APRIL. More specifically the invention provides, compositions of anti-APRIL specific antibodies and methods to use such antibodies in modulating the biological activity APRIL, particularly in inflammatory diseases, inhibition of cell proliferation and cancer.
Patent MD-3370515-T2 (MD)
Inventor: HALL WILLIAM JOHN
IPC: G01N33/558
Filed: 2016-10-21
Abstract: Sunt descrise forme de realizare a sistemului şi a metodei pentru analiza unui fluid de testare pentru a detecta infestările anterioare sau prezente de ploşniţe. Într-o variantă de realizare, metoda poate include primirea fluidului de testare pe o bandă de testare în cadrul dispozitivului de detectare. Banda de testare poate include o porţiune de reacţie şi o porţiune de reactiv care conţine un anticorp sau un fragment de legare la antigen care este conjugat la o particulă colorată. Lichidul de testare poate include antigenul de ploşniţă care reacţionează cu anticorpul conjugat. Dispozitivul de detectare poate include un prim şi un al doilea senzor optic pentru monitorizarea unei reacţii şi, respectiv, a intensităţii culorii de fundal. După trecerea unui interval de timp prestabilit, dispozitivul de detectare determină dacă antigenul de ploşniţe de pat este prezent în fluidul de testare utilizând intensităţile de culoare monitorizate şi pragurile minime şi maxime de intensitate a culorii asociate cu ploşniţele de pat. Apoi, dispozitivul de detectare emite un rezultat folosind un afişaj vizual.
Patent TR-200002118-T2 (TR)
Title: Baldırdaki ülserlerin ve dekubitik ülserlerin tedavisinde pudra müstahzarlarının kullanılması.
Inventor: BOHN MANFRED
IPC: A61P17/02
Filed: 1999-01-11
Abstract: Formülü (I) olan en asagi bir bilesigi içeren pudra müstahzarlari baldir ülserinin veya dekubital ülserlerinin tedavisi için uygundurlar. (sekil var)
Patent TR-200100054-T2 (TR)
Title: Paroksetin metansülfonat
Inventor: JACEWICZ WITOLD VICTOR
IPC: A61K47/36
Filed: 1999-04-23
Abstract: Paroksetin metansülfonat, hazirlama prosesleri, bunu içeren farmasötik terkipler ve terapide kullanimi açiklanmaktadir.
Patent TR-200101225-T2 (TR)
Inventor: MCINTIRE GREGORY LYNN
IPC: A61K49/00
Filed: 1999-11-05
Abstract: Radioactive sources, preferably radioactive seeds, for use in brachytherapy comprising a radioisotope within a sealed biocompatible container, wherein at least one part of a surface of the container is roughened, shaped or otherwise treated so that it is no longer smooth. The surface treatment may enhance the ultrasound visibility of the source and/or reduce the tendency of the source to migrate once implanted in a patient's body. Preferred radioisotopes are palladium-103 and iodine-125.</PTEXT>
Patent TR-200101383-T2 (TR)
Title: Tohumların işlenmesi için pestisit kompozisyonu
Inventor: SCHNEIDERSMANN FERDINAND MARTI
IPC: A01N47/40
Filed: 1999-11-15
Abstract: Mevcut bulus, Insekt ya da Akarina takimi örnekleri ve mikroorganizmalarin kontrol edilmesine yönelik en az dördül bir kompozisyon temin eder ve bu kompozisyon sunlardan olusur: (A) en az bir neonicotinoid ya da phenylpyrazole insektisidinin insektisit yönden etkili bir miktari ve (B1) en az bir phenylamide (acylalanine tipi), (B2) en az bir phenylpyrrole ve (B3) en az bir triazol içeren (B) en az üç fungusidin fungusit yönden etkili bir miktari.
Patent TR-200102239-T2 (TR)
Title: Beyaz kan hücreleri sayımını arttırmak için yöntem ve düzenlemeler.
Inventor: MACFARLAND RONALD TREVOR
IPC: A61K31/395
Filed: 2000-02-02
Abstract: Formül (I)'in bilesikleri kullanilarak hayvan deneklerdeki beyaz kan hücreleri sayimini artirmanin yöntemleri bildirilmistir. Bu bilesikler: Z-baglayici-Z' formülüne sahiptirler veya Z'nin üyelerinden 3-8'i nitrojen atomu olan 9-32 zinciri içeren kendi kendini tahdit eden bir poliamin oldugu ve bu bahsedilen nitrojen atomlarinin birbirinden en az iki karbon atomu ile ayrildigi, ve bahsedilen heterosikl'in, istege bagli olarak, nitrojenin yaninda ek heteroatomlar içerdigi ve/veya ek bir zincir sistemine eriterek birlestirildiginde onun eczacilikla ilgili kabul edilebilir tuzuna sahiptir.
Patent TR-200103605-T2 (TR)
Title: Bulk halinde sürekli filman prosesiyle üretilen ştapel elyaf.
Inventor: AHN JOHN S
IPC: D04H1/42
Filed: 2000-06-16
Abstract: Bu bulus sathi modifiye edilmis stapel elyaf, ve daha da özellikle tamamen akuple bulk halinde bir sürekli filaman (BCF) prosesi ile imal edilen poliester elyaf dolum malzemeleri ve elyaf kümeleri ile ilgilidir.
Patent TR-200201707-T2 (TR)
Inventor: VUILLAUME ANDRE
IPC: D04H3/11
Filed: 2000-11-16
Abstract: The invention concerns a method for producing a complex nonwoven fabric which consists in continuously producing a complex wherein a first web of a cellulosic fibres (4) is continuously sandwiched between two webs of spunbonded filaments (2, 7), and which consists in: producing a first web of spunbonded filaments (2), the bundle of extruded and drawn filaments being received on a mobile conveyor belt (3) in the form of a non-bonded lap; depositing on said web 92) by airlaid process a second web of cellulosic fibres (4); depositing on the textile web (4) a second web (7) of non-bonded continuous filaments; transferring the resulting complex onto an installation (9) for water-jet bonding and hydro-entanglement consolidation; and in drying the nonwoven mixed product and then recuperating it, for example in the form of a cloth wind-up (18).
Patent DE-602004003284-T2 (DE)
Inventor: GRAMPASSI ENRICO
IPC: F25C1/14
Filed: 2004-05-07
Granted: 2007-06-21
Abstract: A machine for dispensing icy beverages such as slushes, sorbets and the like, particularly coffee-flavored ones, comprising at least one tank (3) for containing an icy beverage (B), provided with at least one inlet (4) and at least one outlet (5), elements (7) for agitating the beverage (B), which are arranged inside the tank (3), and at least one refrigeration system (RS) provided with an evaporation unit (EU) associated with the tank (3), and elements (10) for sensing and controlling the temperature of the beverage (B) contained in the tank (3), which are functionally associated with the refrigeration system (RS). <IMAGE>
Patent DE-602004005036-T2 (DE)
Inventor: FAVRET UGO
IPC: D06F58/46
Filed: 2004-08-27
Granted: 2007-11-22
Abstract: A clothes drying machine comprises a drum (1), a fan (5) blowing a first flow of drying air through a drying-air conduit (2) and a motor (7) adapted to drive said fan (5). An auxiliary resistance (10) is placed inside said conduit (8), and means are provided that are able to selectively connect/disconnect said auxiliary resistance (10), preferably said auxiliary resistance (10) may be connected in series to the electric power supply of said electric motor.
Patent DE-602004008037-T2 (DE)
Inventor: PELLEGRIN YVON
IPC: H01L21/68
Filed: 2004-02-05
Granted: 2008-04-30
Abstract: The invention concerns an electrostatic chuck ( 250 ) comprising an upper ceramic ( 205 ) bearing the substrate ( 200 ) to be treated and a lower ceramic ( 215 ) bearing heating elements ( 225 ) and radio frequency electrodes ( 220 ), said ceramics being permanently bonded together. Said ceramics are preferably bonded together by heated glass and the lower ceramic is fixedly assembled to a pedestal, for example through a soldered bonding.
Patent DE-602004009766-T2 (DE)
Inventor: JITARU IONEL DAN
IPC: H02M3/158
Filed: 2004-03-10
Granted: 2008-08-28
Abstract: A DC-DC switching converter device (101), in particular a quarter-brick or eighth-brick device having an industry standard pin out, comprises a pulse-width modulation circuit (132) for driving a power converting switch, a trim connector (109) for adjusting an output voltage of the device, where the device (101) is designed such that the pulse-width modulation circuit (132) is synchronizable to an external oscillator by an external synchronization signal applied to the trim connector. A DC-DC converting circuit comprises a plurality of DC-DC switching converters (101) featuring trim connectors (109) for adjusting output voltages of the converters (101), whereby the converters (101) are connected such that they share a common input bus. It further features a system EMI (electromagnetic interference) filter common to all the DC-DC switching converters (101) and an external oscillator delivering an external synchronization signal to the plurality of DC-DC switching converters (101). The external oscillator is designed such that a frequency of the external synchronization signal is higher than a free running frequency of each of the plurality of DC-DC switching converters (101). The external oscillator is connected to the trim connectors (109) of the DC-DC switching converters (101).
Patent DE-602004010107-T2 (DE)
Inventor: ENING CHRISTIAN
IPC: B60C23/04
Filed: 2004-09-03
Granted: 2008-09-11
Abstract: The arrangement has a magnetic coupling coil (2) including a loop portion (2``) oriented, such that magnetic field in the coil is directed into the loop portion in a direction perpendicular to magnetic field induced by an excitation coil of an interrogation circuit. An antenna coil (10) of a transponder circuit (1), disposed in a winding of the loop portion, is oriented to be induced by the magnetic field induced by the loop portion.
Patent DE-602005002693-T2 (DE)
Inventor: CAPUZZI CARMINE
IPC: A47J31/00
Filed: 2005-08-04
Granted: 2008-07-17
Abstract: The appliance for making and dispensing beverages comprises: a first station (S1) for dispensing water under pressure; a second station (S2), installed downstream of the first station (S1), provided with means (15) for receiving and removably holding a capsule (50) containing water soluble substances; means (202) that punch capsule (50) and sprinkle the water under pressure into the same; conveying means (159A), for directing the water and the substances dissolved therein towards the outside of capsule (50); dispensing means (153), arranged downstream of capsule (50), for directing the water and the substances dissolved therein towards a first spout (90); a third station (S3), installed downstream of the first station (S1), comprising members (35) for the removable grip of a pod (500) containing infusion products; a boiler (901, 902), fed by the first station (S1), moved in approach/removal to and from said pod (500) and forming at the bottom first members cooperating with said gripping members (35) for defining members for holding the pod between the latter; members, associated to the lower portion of the boiler (901, 902), which introduce into pod (500) the heated water coming from the boiler itself (901, 902); conveying members (355) intended for channelling the infusion outwards of pod (500) itself; dispensing members (353) intended for directing the water and the substances dissolved therein towards a second spout (92); control means (C1) associated to a control unit (C) adapted for managing the operation of appliance (M).
Patent DE-602005005468-T2 (DE)
Inventor: KEY PETER
IPC: H04L12/56
Filed: 2005-07-15
Granted: 2009-04-23
Abstract: Known methods for estimating RTT are generally unsuitable for use by a simplex receiver. The term "simplex receiver" is used here to refer to a receiver or destination node which will not be sending data back to an associated transmitter or source node. Known methods typically involve sending specific data transmissions and this is not possible from a simplex receiver. This problem is addressed by making use of flow control mechanisms in communications protocols. By using the flow control mechanisms we have been able to enable a simplex receiver to estimate RTT without the need to send specific data transmissions from the simplex receiver. Advantageously this can be achieved for a simplex receiver provided as a software application provided on a processor such as a personal computer using a conventional operating system. No modification to the communications protocol itself is essential.
Patent DE-602005005756-T2 (DE)
Inventor: HORAN MARTIN
IPC: G01N31/00
Filed: 2005-09-27
Granted: 2009-04-09
Abstract: A liquid analyser has a reactor portion and an associated measurement portion. A sample pump is operable to deliver a liquid sample to a reactor vessel. A base pump supplys a base solution to the reactor vessel. An ozone generator supplies ozone to the reactor vessel. The liquid sample is oxidised in the reactor vessel by means of hydroxyl radicals which are generated using the base solution and ozone to reduce complex components of the liquid sample to their lowest state in solution. The oxidised sample solution is delivered to an optical detector in the measurement portion to determine the concentration of one or more selected materials such as nitrogen, phosphorous or a heavy metal in the oxidised sample solution.