baber/WOPTO huggingface dataset:
Patent NZ-606687-A (NZ)
Title: Ratio based biomarkers and methods of use thereof
Inventor: HEWITT STEPHEN M
IPC: G16B25/10
Filed: 2010-01-13
Abstract: A method of determining cancer prognosis for a subject with a cancer is disclosed. At least two cancer associated proteins in a sample from the subject are identified at least two cancer associated proteins comprise p-AKT and PTEN but not p-mTOR. The at least two cancer associated proteins in the sample are quantified. The at least two cancer associated proteins in the sample are normalised to obtain a normalized value for each cancer associated protein in the sample. The normalized value of the first cancer associated protein is compared with the normalized value of the second cancer associated protein to obtain a biomarker indicator that comprises a ratio of the normalized value of the first cancer associated protein to the normalized value of the second cancer associated protein; and the biomarker indicator is correlated with prognosis of the subject with cancer.
Patent NZ-610467-A (NZ)
Title: Pharmaceutical compositions of imidazoquinoline derivative compounds
Inventor: CAO YU
IPC: A61K9/16
Filed: 2011-12-01
Abstract: Provided is an oral pharmaceutical composition comprising an imidazoquinoline derivative compound of the general formula (I), wherein the variables are defined in the specification, Vitamin E TPGS and polyethylene glycol or polyethylene oxide. A preferred compound in the composition is 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile or 8-(6-methoxy-pyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl-3-trifluoromethyl-phenyl)-1,3-dihydro-imidazo[4,5-c]quinolin-2-one. Further provided are processes for making the compositions, a kit comprising the composition and instructions for its use and related uses of the compositions. The compositions are useful in the treatment of cancer.
Patent NZ-610948-A (NZ)
Title: 5,6-dihydro-imidazo[1,2-a]pyrazin-8-ylamine derivatives useful as inhibitors of beta-secretase (bace)
Inventor: TRABANCO-SUÁREZ ANDRÉS AVELINO
IPC: C07D487/04
Filed: 2011-12-21
Abstract: The present invention relates to novel 5,6-dihydro-imidazo[1,2-a]pyrazin-8-ylamine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer’s disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, cerebrovascular amyloid angiopathy, multi- infarct dementia, Down’s syndrome, dementia associated with stroke, dementia associated with Parkinson’s disease or dementia associated with beta-amyloid. Compounds of the disclosure include: (R)-N-{ 3-[8-amino-3-difluoromethyl-6-methyl-5,6-dihydroimidazo[1,2-a]pyrazin-6-yl]-4-fluorophenyl} -5-fluoropyridine-2-carboxamide, (R)-N-{ 3-[8-amino-2-chloro-3-cyano-6-methyl-5,6-dihydroimidazo[1,2-a]pyrazin-6-yl]-4-fluorophenyl} -5-fluoropyridine-2-carboxamide, (R)-5-methoxy-pyrazine-2-carboxylic acid [3-(8-amino-6-methyl-5,6-dihydro-imidazo[1,2-a]pyrazin-6-yI)-4-fluoro-phenyl]-amide, And (R)-tert-butyl [2-chloro-3-cyano-6-(2-fluoro-5-{ [(5-methoxypyrazin-2-yl)carbonyl]amino} phenyl)-6-methyl-5,6-dihydroimidazo[1,2-a]pyrazin-8-yl]carbamate
Patent NZ-619227-A (NZ)
Title: Glycolate formulation for preserving wood and like materials
Inventor: MAYNARD NIGEL PAUL
IPC: B27K3/52
Filed: 2012-07-27
Abstract: Disclosed are compositions and methods for use in treating lignocellulosic substrates such as lumber, wherein said compositions comprise a preservative or biocidal species, other than boron, in the form of a glycolate formed from a metal salt and a glycol. In a particular embodiment the preservative or biocidal species in the form of a glycolate is an octahedral copper glycolate coordination complex formed from a copper (II) salt and glycerol. The methods may be used for the purpose of, for example, preventing the growth of pest organisms, or for providing other specific properties to the substrate.
Patent NZ-630288-A (NZ)
Title: Process for preparing dasatinib monohydrate
Inventor: PUROHIT PRASHANT
IPC: C07D417/12
Filed: 2013-04-16
Abstract: Provided is a process for preparing N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4- byrimidinyl]amino]-5-thiazole carboxamide monohydrate or Dasatinib monohydrate (formula A). The process comprising the steps of: a) reacting the compound of Formula I with 1-(2-Hydroxyethyl) piperazine (Formula II) in the presence of acetonitrile solvent, an organic base and a phase transfer catalyst; b) heating the reaction mixture at 50-80°C; c) adding water to the reaction mass obtained in step b); d) cooling the reaction mixture to a temperature below 35 °C; e) filtering and drying the material obtained in step d); f) optionally purifying the product obtained from step e); g) isolating the crystalline Dasatinib monohydrate.
Patent NZ-702505-A (NZ)
Title: An electronic apparatus to aid learning
Inventor: HEMAHEMA-TAMATI SOPHIE TAUWEHE
IPC: G09B21/00
Filed: 2007-12-17
Abstract: An electronic apparatus to aid learning includes at least one processor and at least one memory including computer program code. The at least one memory and the computer program code with the at least one processor, causes the apparatus to perform at least the following: display a plurality of displayable components in the form of images on a display screen. Each component is arranged in groups of different types, and each group of components being arranged relative to at least one other group of components to form a preferred arrangement of group, and each component of each group including a discrete element from a range of element selections, and each element being represented in at least one source form and at least one target form. The at least one source form is a form or at least part of the form that is known to a learner, and the at least one target form is form or at least a part of the form that is intended to be learned by the learner. Each component within each group is selectable by a learner to form a pattern desired to be learned by the learner and the elements in the source forms is presentable in a manner to promote the learning of the target forms.
Patent NZ-715539-A (NZ)
Title: Methods for fixing hair and skin
Inventor: PRESSLY ERIC D
IPC: A61Q5/10
Filed: 2014-08-01
Abstract: Compositions, kits, and methods for repairing bonds, for example, disulfide bonds, in hair or on the skin are disclosed. The compositions provide improved conditioning benefit for dry hair or moisturize the skin. The compositions also provide a long lasting moisturized feel and smooth feel to the skin or hair, without feeling greasy. The compositions contain one or more compounds that covalently bind at least two thiol groups in the hair or on the skin. Use of the binding compositions prevents reversion of the repaired bonds to their free thiol state, for at least one week or one month, or more, after a single application of the composition. Improved methods of styling hair, for example permanent hair waving, hair curling, hair coloring or highlighting, and hair straightening, are also provided.
Patent NZ-721542-A (NZ)
Title: Method for utilizing a wireless connection to unlock an opening
Inventor: LOWDER SCOTT
IPC: H04M1/72415
Filed: 2014-12-19
Abstract: The present invention relates to door locks and in particular to controlling operation of door locks wirelessly by authorized users. Bluetooth technology, universally adopted by cell phone manufacturers, is one means of allowing low power and secure wireless access by authorized users for opening door locks. Although convenient for users, opening door locks using phones may result in inadvertent or unintentional unlocking of a door and difficulty in determining the location of a phone using Bluetooth on a desired side of a door. The present invention provides a method and system of operating a lock controlling access to an area secured by a physical barrier from a portable remote device. The method comprises providing a sound frequency detection device on each side of the barrier and operatively connected to a controller for the lock, sending a radio frequency identification signal from the portable remote device to the controller for the lock, receiving the radio frequency identification signal at the lock controller and identifying the remote device as an authorized user of the lock, sending a radio frequency signal from the lock controller to the remote device specifying a sound frequency identification signal to be sent from the portable remote device, sending a sound frequency identification signal from the portable remote device to the lock controller, attempting to detect the sound frequency identification signal with both sound frequency detection devices to determine the side of the barrier from which the sound frequency identification signal is sent from the portable remote device, receiving the sound frequency identification signal at the lock controller and identifying the remote device as an authorized user of the lock, and authorizing operation of the lock if both the radio frequency identification signal and the sound frequency identification signal indicate that the portable remote device is an authorized user.
Patent NZ-724989-A (NZ)
Title: Buprenorphine dimer and its use in treatment of gastrointestinal disorders
Inventor: SINGH NIKHILESH
IPC: A61K31/485
Filed: 2015-04-27
Abstract: The present invention provides a buprenorphine dimer compound, wherein the two buprenorphine portions are linked via an ethylene spacer, wherein the spacer is bonded to the two opioid molecules via an ether bond. Pharmaceutical compositions comprising such a buprenorphine dimer drug are also disclosed, and the use of such compounds in the treatment of gastrointestinal hyperalgesia generally and in particular diarrhea-predominant irritable bowel syndrome.
Patent NZ-730007-A (NZ)
Title: A lateral support for a seat
Inventor: SCARLETT ROYDON MARK
IPC: A61G5/12
Filed: 2017-03-13
Abstract: It is known for wheelchairs to have lateral pads for supporting the sides of the torso of a human user. It is convenient for the pads to be swung out of the way to enable the user easy access to the chair, and then swung back closer to the body and locked in place. It is an object of a preferred form of the invention to go at least some way towards achieving this. In a preferred form the invention there is a lateral support forming part of a seat, comprising a bracket 1, a hinge body 2, a forward plate 3 having padding and a lever 17. The lever 17 is arranged so it can be turned by hand to move a bolt 18 into a pin 5 whereby the hinge body is prevented from swinging about the pin. The lever 17 is also arranged so it can be subsequently turned by hand to cause a cam face 21 of the lever to ride along a complimentary engaging surface 22 of the hinge body. This forces the bolt 18 from the pin 5 thereby freeing the hinge body 2 to swing about the pin 5 and, as a consequence, to swing the plate 3 to facilitate access to the seat.
Patent NZ-739207-A (NZ)
Title: Golf ball game apparatus
Inventor: JOLLIFFE DAVID VICTOR
IPC: A63B71/06
Filed: 2016-07-08
Abstract: A golf facility comprising a ball game apparatus that comprises a plurality of coded balls, each ball having a respective circuit that has a chargeable battery, each circuit being arranged to transmit signals which vary in power in dependence upon the current motion of the respective ball, the facility further comprising a plurality of detector units, wherein movements of the balls are detected by the detector units, wherein data relating to the balls are stored in a database connected to the detector units, the data including the codes of the balls and codes relating to players to whom the balls have been allocated, the golf facility further comprising an apparatus configured to give an automatic indication of a player’s score, wherein the facility further comprises a battery charging system for charging the batteries contained within the balls, each ball is configured to temporarily store, and to intermittently transfer to the detector units and thence to the database, data relating to the movements of the ball and wherein the database further stores data relating to a history of charging cycles which have been applied to the batteries within the balls.
Patent NZ-761754-A (NZ)
Title: Acylated oxyntomodulin peptide analog
Inventor: YANG JAE-SUNG
IPC: C07K14/575
Filed: 2018-08-16
Abstract: The present invention relates to a novel peptide analog of acylated oxyntomodulin and a pharmaceutical composition for preventing and treating obesity or overweightness, or diabetes accompanied by obesity and overweightness, containing the same, wherein the peptides have dual activation efficacy on receptors of GLP-1/glucagon and increased in vivo half-life, which are superior to those of natural oxyntomodulin, and the pharmaceutical composition containing the same is effective in the treatment of metabolic diseases such as obesity and diabetes.
Patent NZ-765827-A (NZ)
Title: Continuous motion packaging machine with carton turning station
Inventor: FORD COLIN
IPC: B65G47/84
Filed: 2019-01-29
Abstract: An article packaging machine and method for turning article packs, the article packaging machine having a turner station for turning article packs moving though the packaging machine. The packaging machine includes a main conveyor (C) extending longitudinally from an upstream end to a downstream end and through the turning station (T). Article packs (11) are carried by the main conveyor spaced and sequentially in the downstream direction through the turner station. The turning station includes two opposed flight drive assemblies (13, 14). Each flight drive assembly includes two cam plates (21, 22) and a turner rod (50). Each cam plate includes an upper cam plate (21) and an associated lower cam plate (22) positioned over one another. Each cam plate defines a track (70) in which a cam follower (56) travels in order to progressively impart transverse movement to the turner rod (50). The turner rods contact the pack in two respective areas to turn the pack 90 degrees. In this operation, the distal ends of the turner rods extend past the pack side walls before being retracted. This extension of the turner rods controls the turning of the pack, especially at high speeds and keep the packs from overturning or turning past the desired amount.
Patent PT-100302-A (PT)
Inventor: GRANDMAIRE JEAN-PAUL
IPC: D06M13/148
Filed: 1992-03-26
Abstract: A fabric softening composition or article that is effective for its fabric softening purpose but preferably excludes ecotoxic quaternary ammonium salt, includes, as a fabric softening component, a PEC, which is an ester of pentaerythritol, an ester of an oligomer of pentaerythritol, an ester of a lower alkoxylated pentaerythritol or an ester of a lower alkoxylated pentaerythritol oligomer, with a suitable dispersing agent, which increases its fabric softening effect remarkably. The fabric softening component is preferably a partial higher fatty acid ester of pentaerythritol or a partial higher fatty acid ester of a pentaerythritol oligomer, the fabric softening composition is an aqueous emulsion or a particulate or powder composition (preferably with the dispersing carrier of the powder composition being a fabric softening bentonite), or is a softergent, and the fabric softening article is an absorbent material with PEC deposited on it or absorbed by it. Also within the invention are processes for softening fibrous materials, in washed laundry, by employing such compositions and articles, and processes for manufacturing described compositions.
Patent PT-100489-A (PT)
Title: Process for the removal of contaminants from used lubricant oil, additive for oil and re-refined oil thus obtained
Inventor: STEVENSON DOUGLAS JOHNSTONE
IPC: C10M/
Filed: 1992-05-14
Abstract: Single-stage process for re-refining used lubricant oils with a view to their reuse as top-grade lubricants. The process makes use of a chemical product and a clay which is activated by acid of the montmorillonite type in a reactor containing the said used oils at high temperatures for a specific period of time. The process dispenses with the need other stages, such as dehydration, thermal fractionation at high temperatures and pre-treatment with acid of the bottom products of the thermally fractionated or dehydrated oil, normally required in conventional systems. Consequently, the novel process requires a short processing time and provides high-grade lubricants with improved performance levels, which are superior to those of the conventional system. The removal of the sludges generated in the conventional stages of pre-treatment with acid also reduces the environmental problems of disposing of such sludges. The process also requires less capital investment and is easier and safer for plant personnel to carry out as it does not give rise to corrosion and does not require the handling of corrosive materials. The invention also relates to an additive for oil and to the re-refined oil obtained using the process of the invention.
Patent PT-103055-A (PT)
Title: Set of solid supports for toxic metal ions removal from aqueous media includes ligands giving high sequestration capacity for e.g. actinodes
Inventor: ESTEVES MARIA ALEXANDRA FEIJO
IPC: C22B3/00
Filed: 2003-12-22
Abstract: The set of solid supports for toxic metal ions removal from aqueous media has ligands of the hydroxypyrimidinofla type and is represented by the formula S-B-L, where (S) is e.g. an inorganic polymeric solid support, (B) is a covalent bond and (L) is the ligand. The supports have high sequestration capacities for e.g. Fe (III), metals of Group IIIA of the Periodic Table and actinides.
Patent PT-104305-A (PT)
Title: Relógio académico
Inventor: GASPAR MARCELO RUDOLFO CALVETE
IPC: G04B19/28
Filed: 2008-12-29
Abstract: O PRESENTE INVENTO DIZ RESPEITO A UM TIPO DE RELÓGIO COM O PONTEIRO DOS MINUTOS EXTENSÍVEL, E TEM COMO OBJECTIVO PROMOVER UMA VIVÊNCIA SIMPLIFICADA DA TRADIÇÃO DO QUARTO DE HORA ACADÉMICO . ESTE PONTEIRO EXTENSÍVEL É CONSTITUÍDO POR UMA EXTREMIDADE PRINCIPAL (1) QUE DÁ A INDICAÇÃO DO TEMPO REAL EM MINUTOS, UMA EXTREMIDADE SECUNDÁRIA (2) QUE DÁ INDICAÇÃO DO INTERVALO DE TOLERÂNCIA E UM ELEMENTO EXTENSÍVEL (3) QUE INTERLIGA AS DUAS EXTREMIDADES DO PONTEIRO. A ABERTURA E O FECHO DESTE PONTEIRO SÃO REALIZADOS POR ACÇÃO DE UM MECANISMO QUE PROMOVE A DESLOCAÇÃO DA EXTREMIDADE SECUNDÁRIA 2 DO PONTEIRO EXTENSÍVEL ACCIONADO POR UM CONJUNTO RODA DENTADA (4), CREMALHEIRA (5), MOLA DE FLEXÃO (6) E ALAVANCA MECÂNICA (7) . O ELEMENTO EXTENSÍVEL 3 PODE SER CONCEBIDO A PARTIR DE UMA PELÍCULA OU FILME EXTENSÍVEL, DOBRADA OU AINDA ENROLADA EM TORNO DA EXTREMIDADE PRINCIPAL 1, SENDO QUE O MATERIAL CONSTITUINTE DESTA PELÍCULA OU FILME PODE SER UMA MEMBRANA ELÁSTICA, UM TECIDO OU UM PAPEL, OU AINDA, OUTRO TIPO DE MATERIAL AJUSTADO À FUNÇÃO. ESTÃO PREVISTAS AINDA VARIANTES PARA O ELEMENTO EXTENSÍVEL DO PONTEIRO DOS MINUTOS, COMO É A DE UTILIZAR RESERVATÓRIO TRANSPARENTE, COM A GEOMETRIA DE 1/4 DE CÍRCULO QUE PODE SER ENCHIDO COM UM FLUIDO DE COLORAÇÃO ESCURA EM QUE A ALIMENTAÇÃO E O VAZAMENTO DO RESERVATÓRIO PODEM SER REALIZADOS POR ACÇÃO DE UM ÊMBOLO DE ACTUAÇÃO MANUAL IMPOSTO POR UMA ALAVANCA MECÂNICA. COMO ALTERNATIVA A ESTA ÚLTIMA SOLUÇÃO, PODE-SE USAR AINDA UM DISPLAY DE CRISTAIS LÍQUIDOS COM A FORMA DE 1/4 DE CÍRCULO ANEXADA ÀS EXTREMIDADES DO PONTEIRO EXTENSÍVEL.
Patent PT-104571-A (PT)
Title: Tijolo compósito de argila e limalha metálica
Inventor: BARTOLO PAULO JORGE DA SILVA
IPC: E04C1/40
Filed: 2009-05-13
Abstract: ESTA INVENÇÃO REFERE-SE A UM TIJOLO MACIÇO NO QUAL FOI INCORPORADA LIMALHA METÁLICA NO INTERIOR QUE LHE PERMITIRÁ RENTABILIZAR MELHOR A EMISSÃO DO CALOR ABSORVIDO APÓS EXPOSIÇÃO À CHAMA DA LAREIRA. ESTE TIJOLO SERÁ MAIS SUSTENTÁVEL, NÃO SÓ PORQUE RENTABILIZARÁ MELHOR A LIBERTAÇÃO DO CALOR, COMO PERMITIRÁ A REUTILIZAÇÃO DAS LIMALHAS METÁLICAS PROVENIENTES DOS DESPERDÍCIOS DAS INDÚSTRIAS METALÚRGICAS EVITANDO, DESTE MODO, RECORRER A NOVAS MATÉRIAS-PRIMAS EM ESTADO VIRGEM.
Patent PT-105497-A (PT)
Title: Processo de demolha de produtos alimentares salgados e suas aplicações
Inventor: SARAIVA JORGE MANUEL ALEXANDRE
IPC: A23L5/20
Filed: 2011-01-21
Abstract: A PRESENTE INVENÇÃO DESCREVE UM PROCESSO DE DEMOLHA DE PRODUTOS ALIMENTARES SALGADOS, NOMEADAMENTE BACALHAU SALGADO OU CARNE SALGADA, QUE COMPREENDE OS SEGUINTES PASSOS: - PREPARAÇÃO DO REFERIDO PRODUTO PARA A DEMOLHA EM RAZÕES VOLUMÉTRICAS VARIÁVEIS ATÉ PELO MENOS 1:20 -VOLUME DE PRODUTO:VOLUME DE ÁGUA DE DEMOLHA; - REALIZAÇÃO DA DEMOLHA A PRESSÕES ENTRE 5- 1000 MPA; - DESCOMPRESSÃO DO PRODUTO; - SEPARAÇÃO DA ÁGUA DE DEMOLHA. ESTE PROCESSO DIMINUI DE MODO MUITO SIGNIFICATIVO O TEMPO DE DURAÇÃO DA DEMOLHA, QUE PELOS PROCESSOS ACTUAIS DEMORA CERCA DE 24 HORAS. O PROCESSO APLICA-SE A QUALQUER TIPO DE PRODUTO, INDEPENDENTEMENTE DA ESPESSURA DO MESMO INTEIRO OU EM POSTAS, COMO LOMBOS, ASAS, ETC.
Patent PT-106012-A (PT)
Title: Método de encaminhamento geográfico para redes veiculares com ligações intermitentes
Inventor: RODRIGUES JOEL J P C
IPC: H04L1/14
Filed: 2011-11-07
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A UM NOVO MÉTODO DE ENCAMINHAMENTO GEOGRÁFICO PARA REDES VEICULARES COM LIGAÇÕES INTERMITENTES, O QUAL INTRODUZ UMA ABORDAGEM DIFERENCIADA AO ENCAMINHAMENTO DE UNIDADES PROTOCOLARES DE DADOS DESIGNADAS POR AGREGADOS, BASEADO NO PARADIGMA DE ''ARMAZENAMENTO, TRANSPORTE E ENVIO DE AGREGADO'' E NA UTILIZAÇÃO DE INFORMAÇÃO DE LOCALIZAÇÃO GEOGRÁFICA (1, 2) PARA AUXILIAR NA TOMADA DE DECISÕES DE ENCAMINHAMENTO (6, 7, 19, 20, 21, 22, 27, 28, 29). PARA AUMENTAR A PROBABILIDADE DE ENTREGA ATEMPADA DE AGREGADOS VIA ROTAS MULTI-SALTO, É COMBINADA A UTILIZAÇÃO DE UM ESQUEMA DE ENCAMINHAMENTO MULTI-CÓPIA COM UM LIMITE ESTRITO NO NÚMERO DE CÓPIAS CRIADO POR AGREGADO, COM UMA ESTRATÉGIA DE COMUTAÇÃO/DESPACHE (21, 22, 28, 29), E COM A UTILIZAÇÃO DE NOTIFICAÇÕES VIA RECIBOS ATIVOS (13, 14, 15, 16, 25).
Patent RO-90509-A (RO)
Inventor: HUBER LUDWIG
IPC: A01N25/10
Filed: 1984-11-30
Abstract: A controlled release composition of biologically active materials is prepared by reacting a biologically active agent, aqueous polyhydroxy polymer, inorganic salt, and optional filler(s), drying the product and then grinding the product to the desire particle size. The product is then used. for example, for controlling pests.
Patent RO-90954-A (RO)
Inventor: CASANOVA MARIA J
IPC: A61K31/4427
Filed: 1985-03-25
Abstract: 1,4-Dihydropyridine derivs. of formula (I) and their acid addn. salts are new. R = OH, 1-4C opt. branched alkoxy which may be substd., such as methoxy or methoxymethoxy, or 2 gps. R on adjacent atoms form an alkylenedioxy gp., such as methylenedioxy or ethylenedioxy n = 1,2 or 3 R1 and R2 = 1-4C opt. branched alkyl which may be substd., such as methyl, ethyl, propyl, isopropyl, butyl, isobutyl, methoxyethyl or 2-pyridylmethyl. -
Patent RU-94003905-A (RU)
Inventor: STEKOL NIKOV L I
IPC: A61Q19/04
Filed: 1994-01-28
Abstract: FIELD: cosmetics. SUBSTANCE: the following substances were added to the cosmetic base: 0.1-0.5 mas. p. vitamin D per 100 mas. p. composition and, additionally: 0.1-0.3 mas. p. hyaluronic acid ad 0.5-1 mas. p. angelicine. Before addition hyaluronic acid is dissolved in water and a mixture of vitamin D and angelicine is dissolved in alcohol. EFFECT: prolonged action, enhanced quality of sunburn.