baber/WOPTO huggingface dataset:
Patent NZ-600728-A (NZ)
Title: Heavy-duty axle-to-beam connection
Inventor: PIERCE PHILLIPPI
IPC: B60G9/02
Filed: 2011-01-17
Abstract: 600728 An axle-to-beam connection for axle/suspension systems includes a pair of U-bolt brackets that extend generally to or beyond a selected centerline of the axle. The U-bolt brackets are located a distance from one another so that the distance between the U-bolt brackets is equivalent to or preferably less than the outside diameter of the axle resulting in a slight deformation of the axle and a compressive preload between the axle and the U-bolt brackets when the axle is seated between the U-bolt brackets. A weld is placed between the U-bolt brackets and the axle at or beyond the horizontal centerline of the axle within the residual compressive stress field on the axle created by the interference fit of the axle into the U-bolt brackets. Means for securing connection of the axle to the beam includes a U-bolt or other similar means to provide additional locating support to the axle.
Patent NZ-612918-A (NZ)
Title: Solid forms of gyrase inhibitor (r)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1h-benzimidazol-2-yl]urea
Inventor: KRAWIEC MARIUSZ
IPC: C07D413/14
Filed: 2012-01-13
Abstract: The disclosure relates to crystalline forms of 8(R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]urea represented by formula (I) and hydrochloride and mesylate salts thereof, which inhibit bacterial enzymes gyrase and/or topoisomerase IV. Also disclosed are pharmaceutical compositions comprising said compound of formula (I) or its salts and their use for treating bacterial infection caused by Mycobacterium tuberculosis, Streptococcus pneumoniae, Staphylococcus epidermidis, Enterococcus faecalis, Staphylococcus aureus, Clostridium difficile, Moraxella catarrhalis, Neisseria gonorrhoeae, Neisseria meningitidis, Mycobacterium avium complex, Mycobacterium abscessus, Mycobacterium kansasii, Mycobacterium ulcerans, Chlamydophila pneumoniae, Chlamydia trachomatis, Haemophilus injluenzae, Streptococcus pyogenes or β-haemolytic streptococci.
Patent NZ-621483-A (NZ)
Title: Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
Inventor: CHUNTHARAPAI ANAN
IPC: C07K16/28
Filed: 2006-11-30
Abstract: Disclosed is an antibody that specifically binds to IL-22, wherein the antibody is (a) an antibody produced by hybridoma 11H4.4 (ATCC Accession No. PTA-7315) (b) an affinity matured form of the antibody of (a); (c) an antigen-binding fragment of the antibody of (a) or (b); or (d) a humanised form of the antibody of (a), (b), or (c).
Patent NZ-625401-A (NZ)
Title: Method for improved transformation using agrobacterium
Inventor: MILLER PAUL DAVID
IPC: C12N15/82
Filed: 2012-12-14
Abstract: Disclosed is a method for plant cell transformation comprising exposing immature embryo plant cells to Agrobacterium cells in a liquid medium containing a non-ionic trisiloxane surfactant, the surfactant having a concentration of 0.001 weight percentage to 0.08 weight percentage in the liquid medium, and wherein the non-ionic trisiloxane surfactant is not a trisiloxane alkoxylate.
Patent NZ-630213-A (NZ)
Title: Methods of treating bladder cancer
Inventor: DESAI NEIL P
IPC: A61P35/00
Filed: 2014-03-13
Abstract: Disclosed is a method of treating bladder cancer in an individual, comprising administering to the individual an effective amount of a composition comprising nanoparticles comprising a limus drug and an albumin. A preferred limus drug is sirolimus (rapamycin). In an embodiment the bladder cancer is non-muscle-invasive bladder cancer. In an embodiment the nanoparticle composition is administered in conjunction with BCG.
Patent NZ-706192-A (NZ)
Title: Mir-18b for use as a marker of cancer progression and target for therapies to treat cancer
Inventor: KASHANI-SABET MOHAMMED
IPC: C12Q1/68
Filed: 2013-09-19
Abstract: The disclosure provides methods for predicting and/or determining whether a subject has cancer based on the level of expression of miR-18b and methods for determining whether a cancer in a subject is progressing or regressing based upon the change of expression levels of miR-18b between two time points, wherein the expression levels of the miR18b gene are measured and the methylation status of a 2.5kB region upstream of the miR-18b gene is determined. The disclosure further provides methods to treat a subject with a cancer by administering a polynucleotide comprising miR-18b and/or an agent that enhances the expression of miR-18b.
Patent NZ-707336-A (NZ)
Title: Treatment methods using adenovirus
Inventor: BREITBART EYAL
IPC: A61K35/761
Filed: 2013-10-17
Abstract: The invention provides methods of reducing or decreasing a size of a tumor or eliminating a tumor or inhibiting, decreasing, or reducing neo-vascularization or angiogenesis in a tumor in a patient by administering an adenovirus comprising a nucleic acid construct comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter. Also provided is a homogeneous population of an adenovirus comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter and its uses thereof.
Patent NZ-709735-A (NZ)
Title: Method and apparatus for generating an infrared illumination beam with a variable illumination pattern
Inventor: JANSSEN COLIN
IPC: G08B13/181
Filed: 2013-01-28
Abstract: A method for generating an infrared (IR) beam for illuminating a scene to be imaged comprises providing at least two IR emitters, including a first IR emitter operable to emit a wide beam component of the IR beam, and a second IR emitter operable to emit a narrow beam component of the IR beam, wherein the wide beam component has a linear profile that has a lower standard deviation than a linear profile of the narrow beam component. The method also comprises selecting a desired linear profile for the IR beam, and selecting a power ratio of power directed to the first IR emitter and power directed to the second IR emitter that produces the IR beam with the desired linear profile when the narrow beam component and wide beam component are combined; and directing power to the first and second IR emitters at the selected power ratio to generate the wide and narrow beam components, and combining the generated wide and narrow beam components to produce the IR beam.
Patent NZ-716730-A (NZ)
Title: Methods, compositions, and devices for supplying dietary fatty acid needs
Inventor: MARGOLIN ALEXEY L
IPC: A23L33/00
Filed: 2013-02-14
Abstract: Provided is a method of preparing a nutritional formula comprising long chain-polyunsaturated fatty acids (LC-PUFAs) in the form of monoglycerides and free fatty acids prior to ingestion by a subject comprising exposing a liquid nutritional composition comprising LC-PUFA triglycerides and/or LC-PUFA esters to a lipase. Further provided is a nutritional formula prepared by this method, and its use for providing nutrition, for improving fat absorption, for improving cognitive ability, for preventing chronic lung disease, and for reducing the length of time a patient requires total parenteral nutrition. Additionally provided are devices comprising immobilised lipases useful in the method of preparation.
Patent NZ-720487-A (NZ)
Title: Seed treatment methods and compositions
Inventor: SMITH R STEWART
IPC: A01N43/16
Filed: 2012-09-10
Abstract: Disclosed herein is a method of enhancing plant growth, comprising treating a seed at least two years prior to planting with a flavonoid, such as chalcones, anthocyanidins, coumarins, flavones, flavanols, flavonols, flavanones, isoflavones, enistein, daidzein, formononetin, naringenin, hesperetin, luteolin and apigenin wherein, upon harvesting, the plant exhibits at least one of increased plant yield measured in terms of bushels/acre, increased root number, increased root length, increased root mass, increased root volume and increased leaf area, as compared to a plant harvested from a control seed, optionally a control seed treated with the flavonoid just prior to or within a week or less of planting.
Patent NZ-725331-A (NZ)
Title: Internet protocol based audio alert system
Inventor: THOMPSON PAUL
IPC: G08B3/10
Filed: 2015-04-01
Abstract: An internet protocol based audio alert system for managing security across a site has a network of a central server computer (12), a central client computer (14) and a remote client computer (30) communicating across the internet (16) with a plurality of programmable edge devices (18). The programmable edge devices (18) control the operation of audiovisual input means and audiovisual output means (20, 22, 24, 26) located across the site. The programmable edge devices (18) are programmed with software to enable them to store alert messages, which are short alert messages, and send the alert messages to the audiovisual output means where the alert messages are broadcast in response to triggers received by the audiovisual input means. The audiovisual output means include a loudspeaker assembly (22) connected to each programmable edge device.
Patent NZ-726323-A (NZ)
Title: Antimicrobial compositions
Inventor: PATTON THOMAS
IPC: A61K38/44
Filed: 2014-04-30
Abstract: Storage-stable compositions for generating antimicrobial activity are described. The compositions comprise an enzyme that is able to convert a substrate to release hydrogen peroxide, and an unrefined natural substance, such as a honey, that includes a substrate for the enzyme. In certain embodiments, the enzyme is a purified enzyme. In other embodiments, the substrate lacks catalase activity, and the enzyme is additional to any enzyme activity able to convert the substrate to release hydrogen peroxide that may be present in the unrefined natural substance. The storage-stable compositions do not include sufficient free water to allow the enzyme to convert the substrate. Use of the compositions to treat microbial infections and wounds is described, as well as methods for their production.
Patent NZ-728764-A (NZ)
Title: Breathable gas apparatus with humidifier
Inventor: LITHGOW PERRY DAVID
IPC: B29C41/22
Filed: 2004-06-21
Abstract: A breathable gas supply apparatus for treatment of respiratory disorders including a flow generator with an air inlet on a rear wall, the air inlet configured to provide a supply of ambient air to a blower of the flow generator; a water container with a first air opening (716), a second air opening (801), a top portion, a side surface having the second air opening therein and a bottom portion, the bottom portion having a heat conducting surface, the water container including a tub (698) to contain water and a tub lid (700) pivotably moveable relative to the tub, the first and second air openings being located on the tub lid, the water container including a tub seal (699) between the tub and the tub lid, the tub lid having a sloped surface to direct airflow downward towards the bottom portion of the water container; a base (rear cover 803 and front cover 602) with a heater (plate 632 with ceramic heater pad 800), the base being configured to receive the water container; a base lid pivotably attached to the base, the base lid having a locking mechanism to secure the water container; a lid seal between the base lid and the tub lid when the water container is received in the base; an outlet pipe for connection with an air delivery tube in use; a first gas flow port (676) aligned with and in a facing arrangement with the first air opening when the water container is received in the base; a second gas flow port (722) aligned with and in a facing arrangement with the second air opening when the water container is received in the base; and a peripheral seal (722) between the second gas flow port and the second air opening, the second air opening being surrounded by a substantially planar and substantially rectangular sealing surface of the water container that aligns with a substantially rectangular portion of the peripheral seal when the water container is received in the base to create a substantially sealed air path between the peripheral seal and the second air opening without the need to establish tubular interconnection between the base and the water container. The water container and the base include complementary configurations that facilitate alignment of the water container with respect to the base to ensure alignment between the first air opening and the first gas flow port. The water container is removable from the base and then refillable with water without requiring disengagement of the air delivery tube from the outlet pipe. The first air opening, the second air opening, the first gas flow port and the second gas flow port are part of a flow path between the flow generator and the outlet pipe when the water container is received in the base. The lid seal includes a channel which mates with a rim on the base lid.
Patent NZ-734628-A (NZ)
Title: (2s,4r)-5-(5’-chloro-2’-fluorobiphenyl-4-yl)-4-(ethoxyoxalylamino)-2-hydroxymethyl-2-methylpentanoic acid
Inventor: THALLADI VENKAT R
IPC: C07C233/56
Filed: 2016-02-10
Abstract: In one aspect, the invention relates to a compound of the structure: (1), or a pharmaceutically acceptable salt thereof, and a crystalline form of this compound, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this compound; methods of using this compound; and processes for preparing this compound.
Patent NZ-737924-A (NZ)
Title: Condensed imidazolylimidazoles as antiviral compounds
Inventor: YANG ZHENG-YU
IPC: C07D491/052
Filed: 2012-11-16
Abstract: Disclosed is a method for the synthesis of velpatasvir (methyl { (2S)-1-[(2S,5S)-2-(9-{ 2-[(2S,4S)-1-{ (2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl} -4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl} -1,11-dihydroisochromeno[4’,3’:6,7]naphtho[1,2-d]imidazol-2-yl)-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl} carbamate) or a pharmaceutically acceptable salt thereof, comprising: i) reacting tert-butyl (2S,4S)-2-[5-(2-{ (2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl} -1,11-dihydroisochromeno[4’,3’:6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate with hydrochloric acid in ethanol to provide the deprotected intermediate; and ii) contacting the crude product obtained in step i) in dimethylformamide with (R)-2-(methoxycarbonylamino)-2-phenylacetic acid, in the presence of diisopropylethylamine and COMU ((1-cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate) to form velpatasvir.
Patent NZ-756892-A (NZ)
Title: Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof
Inventor: VASILJEVA OLGA
IPC: C07K16/46
Filed: 2014-09-25
Abstract: The invention relates to polypeptides comprising an antibody or antigen-binding fragment thereof, a cleavable moiety and a masking moiety. The cleavable moiety is a substrate for a protease and comprises an amino acid sequence selected from the group consisting of: AVGLLAPP (SEQ ID NO: 31), ALGLLRLP (SEQ ID NO: 470), ALGLLSLP (SEQ ID NO: 471) and ASGLLRFP (SEQ ID NO: 472) . Further described are methods of making and using these polypeptides in a variety of therapeutic, diagnostic and prophylactic indications.
Patent NZ-761085-A (NZ)
Title: Spacecraft servicing devices and related assemblies, systems, and methods
Inventor: NICHOLSON JAMES GARRET
IPC: B64G1/00
Filed: 2018-07-20
Abstract: A spacecraft servicing system, comprising a spacecraft servicing device 180 carrying multiple detachable pods 102 which have at least one spacecraft servicing component. The spacecraft servicing device 180 is configured to transfer the pod 102 to a target spacecraft using the propulsion of the spacecraft servicing system. The spacecraft servicing device 180 is configured to remain in physical contact with the target spacecraft until the pod 102 is secured to the spacecraft, and then to leave. The spacecraft servicing component of the pod 102 comprises a thruster assembly configured to alter the orbit or a velocity of the target spacecraft which can allow life extension or better targeting of the spacecraft.
Patent PT-100506-A (PT)
Inventor: GOULAIT DAVID JOSEPH KENNETH
IPC: D04H1/42
Filed: 1992-05-20
Abstract: A female component is provided for engaging a complementary hook component in a refastenable fastening device. The female component comprises a nonwoven web secured to a backing. The nonwoven web has characteristics that are specifically suited for entangling and holding the hooks of the mating hook component. The nonwoven web has a basis weight of between about 6 and about 42 grams/meter2. The nonwoven web may comprise, among other types of nonwovens, a carded web with fibers between about 2.5 cm. and about 13 cm. long, or a spunbonded web with continuous length fibers. The denier of the fibers should be between about 0.5 and about 15. The total area occupied by any bonds between the fibers comprising the nonwoven web is less than about six percent of the total area of the web. The nonwoven web is secured to the backing, preferably autogeneously. The total area occupied by both the bonds between the fibers comprising the nonwoven web and by the bonds between the nonwoven web and the backing is between about 10 percent and about 35 percent of the total area of the female component. A fastening device having a hook fastening component and a female component that comprises the nonwoven female component of the present invention is also provided. The fastening device can be used on disposable articles, such as disposable diapers.
Patent PT-101104-A (PT)
Title: Improved hydraulic shaping device
Inventor: PACHECO JOSE ANTONIO BESSA
IPC: B21D5/00
Filed: 1992-11-30
Abstract: Device, especially of the ascending type, which essentially comprises a fixed upper apron 1 which carries a punch 9, a movable lower apron 2, which carries a die 10, hydraulic actuating means 3, 4 and a pedal 7 whereby the operator is able to control these actuating means and therefore the operation of shaping plates. The device according to the invention is characterized essentially in that means are provided which make it possible to accelerate the downward movement of the movable apron. In addition to this provision is also made for systems for regulating the depth of shaping in order to adjust and fix the movable apron in the structure of the machine, in order to damp the movable apron in its rapid downward movement and in order effortlessly to control the actuating means by means of a pedal controlled by the operator. Figures 1a, b and c. <IMAGE>
Patent PT-101152-A (PT)
Title: Dye-transfer-inhibiting enzyme detergent compositions
Inventor: BUSCH ALFRED
IPC: C11D3/386
Filed: 1992-12-22
Abstract: Detergent compositions which prevent the transfer of dye between fabrics during washing comprising an enzyme which has a peroxidase activity, hydrogen peroxide or a hydrogen peroxide precursor or an enzyme system capable of generating hydrogen peroxide, an additional oxidizable substrate and a cellulase, compositions characterized in that the cellulase accounts for at least 10% removal of immobilized carboxymethyl cellulose radioactively labelled in accordance with the C14 CMC method at 25 x 10-6% by weight of the washing test solution are described. In accordance with this invention a preferred cellulase essentially comprises a homogeneous component of endoglucanase which is immunoreactive with the monoclonal antibody created against a partly purified cellulase 43 KD derived from Humicola insolens DM 1800.
Patent PT-102106-A (PT)
Title: High-performance securing cable
IPC: D07B1/04
Filed: 1998-02-04
Abstract: Process for manufacturing a high-performance securing cable that is light in weight and easy to handle. To this end, the cable manufactured by the present process is presented as a cable that is easy to grip and that at the same time is balanced and durable. The cable that is the object of the present process consists of secondary cables (8 x 1) with four cords with an S-shaped twisting direction and four cords with a Z- shaped twisting direction, that are braided together. The secondary cables (8 x 1) are arranged in concentric layers and covered by a braided outer. <IMAGE>
Patent PT-105443-A (PT)
Title: Dispositivo e método para transformar representações ternárias em binárias e vise-versa
Inventor: MARTINS FERREIRA NELSON
IPC: H03M5/16
Filed: 2010-12-21
Abstract: A PRESENTE INVENÇÃO RELATA UM MÉTODO CONSIDERADO INOVADOR PARA CONVERTER PALAVRAS (CADEIAS DE CARACTERES) DO SISTEMA TERNÁRIO (NOS SÍMBOLOS 0, 1 E 2) PARA O SISTEMA BINÁRIO. O MÉTODO APRESENTANDO TEM POR BASE UM DISPOSITIVO, BASEADO NUMA MÁQUINA DE ESTADO FINITO, QUE PERMITE ESTABELECER UMA CORRESPONDÊNCIA BIUNÍVOCA ENTRE O CONJUNTO DAS PALAVRAS TERNÁRIAS (SEQUÊNCIAS DE ZEROS,UNS E DOIS) E O CONJUNTO DAS PALAVRAS BINÁRIAS (SEQUÊNCIAS DE ZEROS E UNS). O PROCESSO PODE SER INVERTIDO, PELA SIMPLES EXECUÇÃO DE CADA UM DOS SEUS PASSOS PELA ORDEM INVERSA, OBTENDO-SE ASSIM UM MÉTODO, TAMBÉM CONSIDERADO INOVADOR, PARA A CONVERSÃO DO SISTEMA BINÁRIO NO SISTEMA TERNÁRIO. O MÉTODO APRESENTA AINDA A CARACTERÍSTICA DE PERMITIR UM PROCESSAMENTO SEQUENCIAL PARA PALAVRAS DE GRANDE DIMENSÃO. ESTE PROCESSO TEM COMO PRINCIPAL APLICAÇÃO A TRANSFORMAÇÃO DE UM NÚMERO REPRESENTADO NO SISTEMA TERNÁRIO PARA O SEU EQUIVALENTE NO SISTEMA BINÁRIO, OU VICE-VERSA. OUTRAS APLICAÇÕES SÃO POR EXEMPLO O ENVIO DE INFORMAÇÃO CODIFICADA EM BINÁRIO POR CANAIS TERNÁRIOS OU AINDA O ENVIO DE SEQUÊNCIAS DE INFORMAÇÃO TERNÁRIA, DE COMPRIMENTO ARBITRÁRIO, BIT A BIT, DE ACORDO COM A SUA REPRESENTAÇÃO BINÁRIA. NO FUTURO, ESTA INVENÇÃO PODERÁ AINDA SER UTILIZADA NA COMUNICAÇÃO COM COMPUTADORES TERNÁRIOS.
Patent PT-106246-A (PT)
Title: Goniómetro cirúrgico
Inventor: MARTINS JOSE MANUEL RODRIGUES COSTA
IPC: A61B17/00
Filed: 2012-04-07
Abstract: O PRESENTE MODELO, DESIGNADO POR GONIÓMETRO CIRÚRGICO, É CONSTITUÍDO POR DOIS COMPONENTES: UMA BASE PRISMÁTICA RETANGULAR COM UM RECORTE PARA ADAPTAÇÃO AO GRANDE TROCÂNTER DO FÉMUR E UM COMPONENTE CIRCULAR SERVINDO PARA MARCAÇÃO DE ÂNGULOS DURANTE UMA CIRURGIA, ENTRE 0º E 60º, EM QUALQUER OSSO, QUANDO HÁ NECESSIDADE DE UMA REFERÊNCIA ANGULAR EM CASOS DE CORREÇÃO NO ALINHAMENTO DE DIÁFISE ÓSSEA.
Patent PT-106310-A (PT)
Title: Peças de vestuário com propriedades terapêuticas e o seu uso no tratamento da psoríase e outras doenças
Inventor: OLIVEIRA INES RAPOSO DE
IPC: A61K9/00
Filed: 2012-05-14
Abstract: A PRESENTE INVENÇÃO RELACIONA-SE COM PEÇAS DE VESTUÁRIO DESENHADAS DE ACORDO COM AS METODOLOGIAS CORRENTES NO DESIGN DE MODA, COM PROPRIEDADES TERAPÊUTICAS COMPREENDENDO MATERIAIS TÊXTEIS SUAVES E ANTI-ALÉRGICOS CUJAS FIBRAS CONTÊM MICROCÁPSULAS ACOPLADAS, QUE ENGLOBAM COMPOSIÇÕES FARMACEUTICAMENTE ACEITÁVEIS DE AÇÃO TÓPICA E CONTENDO MAGNETOS POSICIONADOS EM LOCAIS ESPECÍFICOS DAS REFERIDAS PEÇAS DE VESTUÁRIO. DESTA FORMA, A PRESENTE INVENÇÃO É ÚTIL NO TRATAMENTO DA PSORÍASE E DE OUTRAS DOENÇAS, NA MEDIDA EM QUE UTILIZA OS PRINCÍPIOS DA MEDICINA TRADICIONAL CHINESA, EM PARTICULAR A SINERGIA ENTRE A ACUPUNCTURA POR MAGNETOTERAPIA E A FITOTERAPIA INTEGRADOS NO VESTUÁRIO COMUMMENTE UTILIZÁVEL. A PRESENTE INVENÇÃO TEM ASSIM APLICAÇÃO NA INDÚSTRIA TÊXTIL, DO VESTUÁRIO E DE MODA, BEM COMO NA ÁREA DA SAÚDE, CONTRIBUINDO PARA A MELHORIA DA QUALIDADE DE VIDA DOS PACIENTES SUJEITOS A TRATAMENTO DAS DOENÇAS DE PELE, TAIS COMO A PSORÍASE, FUNCIONANDO TAMBÉM COMO UM COADJUVANTE AO TRATAMENTO DE PATOLOGIAS DE OUTRA NATUREZA.