baber/WOPTO huggingface dataset:
Patent DE-69527049-D1 (DE)
Inventor: AMMONS STEVE
IPC: C12N15/09
Filed: 1995-03-13
Granted: 2002-07-18
Abstract: Improved therapeutic uses of bactericidal/permeability-increasing protein (BPI) involve use of BPI protein product formulations in the form of physiologically stable dimeric associations of BPI protein product monomers characterized by enhanced in vivo biological activity. Preferred formulations include 50 percent or more by weight dimeric product.
Patent DE-69527633-D1 (DE)
Inventor: DECKER PETER
IPC: H04L1/00
Filed: 1995-10-23
Granted: 2002-09-05
Abstract: 1. The invention relates to a method for transmitting packet data in an air interface of digital cellular radio telephone system based on a hybrid forward error correction/automatic repeat request, i.e. FEC/ARQ type II. comprising the following steps for each packet: a) encoding the bits of the packet of user data, header and frame check sequence, using error correcting codes and storing the resulting bits for transmission at the sender side; b) transmitting of a predefined part of the encoded bits that is bigger than the original packet; c) collecting and storing all received data at the receiver side with a storage capacity big enough to store at least the encoded bits of one packet; d) deciding on transmission success at the receiver side, based on the stored data and sending a positive acknowledge (ACK) if the transmission has been decided to be successful and a negative acknowledgement (NAK) if not; e) checking at the sender side of the positive or negative acknowledgement (ACK or NAK) and going to step b) in case of negative acknowledge (NAK) otherwise in case of positive acknowledgement (ACK) the transmitting of the packet is being completed and the receiver storage is cleared. With this method optimum throughput in response to a fluctuation in the error rate on a packet radio channel is procided.   <IMAGE>   <IMAGE>
Patent DE-69531699-D1 (DE)
Inventor: HILGERS LUUK
IPC: A61K39/39
Filed: 1995-12-21
Granted: 2003-10-09
Abstract: Vaccine adjuvants comprising a sulpholipid polysaccharide in combination with an interface-forming constituent. The invention also provides a method for preparing a vaccine by emulsifying an aqueous solution of an antigen and a sulpholipid polysaccharide. The adjuvants are stable at high temperatures, and are at least as effective as conventional adjuvants. Their local toxicity, i.e. their reactogenicity, is generally lower than that of conventional adjuvants.
Patent DE-69602756-D1 (DE)
Inventor: CUTTITTA FRANK
IPC: A61P31/10
Filed: 1996-08-16
Granted: 1999-07-08
Abstract: The methods of the present invention demonstrate that adrenomedullin (AM) is expressed in human cancer cell lines of diverse origin and functions as a universal autocrine growth factor driving neoplastic proliferation. The present invention provides for AM peptides and AM antibodies useful in therapeutic, pharmacologic and physiologic compositions. The present invention additionally provides for methods of diagnosis, treatment and prevention of disease utilizing compositions comprising the AM peptides and antibodies of the present invention. The methods of the present invention also provide for experimental models for use in identifying the role of AM in pancreatic physiology. The methods pertaining to rat isolated islets have show that AM inhibits insulin secretion in a dose-dependent manner. The monoclonal antibody MoAb-G6, which neutralizes AM bioactivity, was show by the methods of the present invention to increase insulin release fivefold, an effect that was reversed by the addition of synthetic AM.
Patent DE-69610075-D1 (DE)
Inventor: HAYNES PHILIP ASHLEY
IPC: H04M1/05
Filed: 1996-01-25
Granted: 2000-10-05
Abstract: PCT No. PCT/GB96/00167 Sec. 371 Date Aug. 19, 1997 Sec. 102(e) Date Aug. 19, 1997 PCT Filed Jan. 25, 1996 PCT Pub. No. WO96/23373 PCT Pub. Date Aug. 1, 1996Audio apparatus comprises a base unit including circuitry for generating electrical signals representing sounds and at least one earphone adapted to receive the electrical signals and to reproduce sounds represented by the signals, in which the apparatus is provided externally with a terminal arranged so that it can be positioned in use in contact with or in close proximity to the surface of the user's body. The circuitry is arranged to supply to the terminal signals which are transmitted through the user's body, the or each earphone is provided with a terminal arranged so that it can be positioned in use in contact with or in close proximity to the surface of the user's body so as to receive signals transmitted from the terminal through the user's body, and the or each earphone includes receiving circuitry arranged to receive the signals. The earphones may be embodied in a pair of spectacles, and may be adjustable between a first position behind the ear and a second position in or more adjacent the ear.
Patent DE-69611770-D1 (DE)
Inventor: BOUWENS ELISABETH CORNELIA MAR
IPC: A23F3/16
Filed: 1996-08-21
Granted: 2001-03-22
Abstract: A method of inducing the formation of colour determining compounds in a tea-based food product, characterised in that the tea leaves are treated with an exogenous laccase, polyphenol oxidase or peroxidase, in combination with a pretreatment with a tannase. Also, a treatment with a fungal laccase form a Pleurotus species can be performed to enhance the colour of a tea-based product.
Patent DE-69615169-D1 (DE)
Inventor: JORGENSEN KROGH
IPC: A61P25/00
Filed: 1996-04-01
Granted: 2001-10-18
Abstract: The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
Patent DE-69620742-D1 (DE)
Inventor: TUUNANEN ARI
IPC: G01S5/00
Filed: 1996-01-19
Granted: 2002-05-23
Abstract: PCT No. PCT/FI96/00041 Sec. 371 Date Jul. 18, 1997 Sec. 102(e) Date Jul. 18, 1997 PCT Filed Jan. 19, 1996 PCT Pub. No. WO96/22547 PCT Pub. Date Jul. 25, 1996A method for determining the position of a feed beam (3a to 3c) of a rock drilling equipment so that first, the position of a base (1) of the rock drilling equipment relative to rock is determined in the general system of coordination and after that, the position of the feed beam (3a to 3c) relative to the base (1) is measured. Measuring devices (6a to 6c) fixedly mounted in the base (1) at a distance from one another and at least two measuring devices (9a to 9c, 10a to 10c) attached to the feed beam at a distance from one another at a predetermined position are used in the method, whereby at least some of the measuring devices comprise a transmitter and at least some a receiver, respectively. The position of the feed beam (3a to 3c) relative to the base is measured, for example, by using the propagation time of the oscillation energy transmitted by each transmitter to various receivers and by calculating on the basis of this the position of the measuring devices (9a to 9c, 10a to 10c) of the feed beam relative to the measuring devices (6a to 6c) mounted in the base (1) and based on this, by calculating the position of the feed beam relative to the base (1) and thus relative to the general coordination of the rock.
Patent DE-69621022-D1 (DE)
Inventor: VOLONTE CINZIA
IPC: A61P25/04
Filed: 1996-07-24
Granted: 2002-06-06
Abstract: This invention relates to the use of agonists or antagonists of P2 purinoceptors for the prevention of glutamate-evoked cytotoxicity and in particular use of Basilen Blue D-3G (Reactive Blue 2), Cibacron Blue 3GA and 5-adenylylimidodiphosphate (AMPPNP). In the presence of cytotoxic concentrations of glutamate, these compounds sustain cellular survival of central nervous system (CNS) neurons, such as for example postnatal rat cerebellar granule neurons.
Patent DE-69623435-D1 (DE)
Inventor: TSUTSUI HIROSHI
IPC: F16H61/04
Filed: 1996-06-20
Granted: 2002-10-10
Abstract: A control system for an automatic transmission, comprising: a fluid transmission unit (12) connected to an engine (10); a clutch (C1); a hydraulic servo (C-1); output RPM detecting means (47) for detecting the output RPM of the fluid transmission unit (12); oil pressure generating means for generating the oil pressure to be fed to the hydraulic servo; and a control unit (40). This control unit includes: booster means (105) for raising the oil pressure according to preset characteristics; change rate detecting means (103) for detecting the RPM change rate of the output RPM in a preset section at the applied of the clutch; and correction means (104) for correcting the characteristics by comparing the detected RPM change rate and a reference RPM change rate. The change rate detecting means (103) detects the RPM change rate only when the output RPM at the time of starting the engagement of the clutch (C1) is higher by a preset value than the maximum of the output RPM in the preset section. <IMAGE>
Patent DE-69625264-D1 (DE)
Inventor: VUILLEMIN BRUNO
IPC: C08L33/04
Filed: 1996-03-15
Granted: 2003-01-23
Abstract: New thermoplastic PVC compsns. comprising in addn. to PVC,heat resistant and shock resistant additives the heat resistant additive is a syndiotactic polymethyl methacrylate polymer with a degree of tacticity of at least 70%. Pref. the compsn. contains 30-99% PVC,1-70% of syndiotactic PMMA, and 1-30% of the anti-shock additive.
Patent DE-69627075-D1 (DE)
Inventor: LARRUCEA HENRY
IPC: A63C17/22
Filed: 1996-06-21
Granted: 2003-05-08
Abstract: A wheel for an in-line skate includes a hub having a central core. First and second anchors extend radially from the core. The anchors are positioned on the core in spaced apart relation to define a material-receiving volume between the anchors. A synthetic plastics material is moulded to the core, surrounding each of the anchors and filling the material-receiving volume. <IMAGE>
Patent DE-69631069-D1 (DE)
Inventor: NIKOLCHEV JULIAN
IPC: A61F6/06
Filed: 1996-05-21
Granted: 2004-01-22
Abstract: The invention provides intrafallopian devices and non-surgical methods for their placement to prevent conception. The efficacy of the device is enhanced by forming the structure at least in part from copper or a copper alloy. The device is anchored within the fallopian tube by imposing a secondary shape on a resilient structure, the secondary shape having a larger cross-section than the fallopian tube. The resilient structure is restrained in a straight configuration and transcervically inserted within the fallopian tube, where it is released. The resilient structure is then restrained by the walls of the fallopian tube, imposing anchoring forces as it tries to resume the secondary shape.
Patent DE-69634490-D1 (DE)
Inventor: MIAN ALEC
IPC: G01N33/49
Filed: 1996-12-05
Granted: 2005-04-21
Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The microsystem platforms of the invention are also provided having system informatics and data acquisition, analysis and storage and retrieval informatics encoded on the surface of the disk opposite to the surface containing the fluidic components. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.
Patent DE-69634726-D1 (DE)
Inventor: JACOBS KENNETH
IPC: C07K16/18
Filed: 1996-07-18
Granted: 2005-06-16
Abstract: An antibody that specifically reacts with a protein comprising an amino acid sequence selected from the group consisting of:  (a) the amino acid sequence of SEQ ID NO:2; (b) the amino acid sequence of SEQ ID NO:2 from amino acids 11 to 163; (c) the amino acid sequence of SEQ ID NO:2 from amino acids 29 to 163; (d) the amino acid sequence of SEQ ID NO:2 from amino acids 31 to 163; and (e) a fragment of the amino acid sequence of SEQ ID NO:2 having a CTLA-8 activity chosen from one or more of induction of expression or secretion of  gamma -IFN, IL-6, or IL-8, or inhibition of angiogenesis.
Patent DE-69637155-D1 (DE)
Inventor: BRISKIN MICHAEL J
IPC: C07K14/705
Filed: 1996-02-12
Granted: 2007-08-23
Abstract: The present invention relates to isolated and/or recombinant nucleic acids which encode primate MAdCAMs, and to proteins or polypeptides referred to herein as isolated and/or recombinant primate MAdCAMs. The invention further relates to recombinant nucleic acid constructs, comprising a nucleic acid which encodes a primate MAdCAM of the present invention, a portion thereof, or a variant; to host cells comprising such constructs, useful for the production of recombinant proteins; the use of nucleic acids and/or proteins in assays to identify inhibitors (e.g., antagonists) of primate MAdCAM function; and to antibodies reactive with primate MAdCAM, which are useful in in vitro methods, diagnostic and/or therapeutic applications. The invention also relates to the treatment of individuals, particularly humans, suffering from a disease (e.g., inflammatory bowel disease) associated with leukocyte recruitment to the gastrointestinal tract or other tissues, for example, as a result of binding of leukocytes to cells expressing the molecule MAdCAM (gut-associated endothelium), comprising administering to the individual an effective amount of an agent, such as an antibody which inhibits the binding of leukocytes to MAdCAM.
Patent DE-69702771-D1 (DE)
Inventor: BOUSFIELD ANTHONY
IPC: F25D11/00
Filed: 1997-10-01
Granted: 2000-09-14
Abstract: A refrigerator capable of being internally illuminated wherein the illumination is provided by an edge-lit panel of a substantially transparent material having two opposed surfaces of which at least one is within the refrigerator and on which a matrix of dots is applied so as to produce a light piping effect internally in to the refrigerator and wherein the light source of the edge-lit panel is located within the enclosed space of the refrigerator. One or more edge-lit panels may be used, which may be shelf of the refrigerator, or its side panels, back panel or roof panel. The edge-lit panel may be form from a transparent acrylic sheet, preferably containing an optical brightner. Protective transparent or translucent layer and a light diffuser may be applied to the surface carrying the matrix of dots. The refrigerators wherein the illumination provided by the edge-lit system according to the present invention have light more evenly distributed throughout the refrigerators and could be effectively illuminated by a light source of reduced wattage, thus reducing problems associated with dissipation of heat within the internal chambers of refrigerators.
Patent DE-69703579-D1 (DE)
Inventor: VAN DUIJNHOVEN GERARDUS
IPC: C08F20/22
Filed: 1997-02-12
Granted: 2000-12-28
Abstract: PCT No. PCT/NL97/00055 Sec. 371 Date Mar. 1, 1999 Sec. 102(e) Date Mar. 1, 1999 PCT Filed Feb. 12, 1997 PCT Pub. No. WO97/29903 PCT Pub. Date Aug. 21, 1997A method for producing optical rod-shaped graded-index polymer preform by making the composition of the preform near the core differ from the composition of the shell of the preform by polymerization with rotation of a mixture containing the starting substances, whereby a mixture comprising various monomers is rotated and that after achieving a distribution of the monomers, the polymerization is carried out with rotation of the mixture, or that a monomer and thermoplastic polymer-containing mixture, whereby said monomer is different from the monomer from which said polymer has been prepared, is rotated and that, after achieving a distribution of said monomer and polymer, the monomer present in said mixture is subsequently polymerized with rotation, in which both cases the rotation is carried out with a diameter dependent rotation velocity, represented by the following general equation: rpm>10,000 d-0.5 wherein: rpm=rotation velocity, revolutions per minute d=diameter of the preform (cm). The invention furthermore relates to optical lenses and fibres formed of the polymer preform thus produced.
Patent DE-69714729-D1 (DE)
Inventor: SLESINGER M
IPC: A47F11/10
Filed: 1997-04-12
Granted: 2002-09-19
Abstract: A modular furniture system is provided having vertical members with internal conductors. The conductors are coupled to a source of low voltage electrical power such that adjacent vertical members are of differing electrical polarity. Support members for use in the modular furniture system are designed to make electrical contact with the internal conductors when engaged in a vertical member. An electrical device, such as a light fixture, may be coupled between a pair of brackets engaged in vertical members of opposite polarity, energizing the electrical device. Embodiments are provided for use in merchandising displays and office partition systems.
Patent DE-69715924-D1 (DE)
Inventor: BASTIEN JEAN-PAUL
IPC: G06F9/445
Filed: 1997-04-25
Granted: 2002-10-31
Abstract: A receiver/decoder for use in a digital satellite radio or television system includes a decoder and means to accommodate a credit or bank card carrying a microprocessor, and means to interact with said microprocessor when the credit or bank card is inserted into an operative position in said receiver/decoder in order to enable data carried by said credit or bank card to be read and data to be input to the microprocessor carried by said credit or bank card. A PIN number may be transmitted to the receiver/decoder in a secure fashion by means of a remote controller, which is also described. Applications of the invention include Pay-Per-View television, teleshopping and telebanking. <IMAGE>
Patent DE-69725338-D1 (DE)
Inventor: LUKE RICHARD WILLIAM ARTHUR
IPC: C07K1/06
Filed: 1997-12-09
Granted: 2003-11-06
Abstract: The invention concerns pharmacologically useful peptide derivatives of the formula (I): P-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-Q, and pharmaceutically acceptable salts thereof, wherein either AA3 together with AA4, or AA4 together with AA5, or AA6 together with AA7 form a group of formula (II):in which Ra is selected from hydrogen and (1-4C)alkyl, and the remainder of AA1, AA2, AA3, AA4, AA5, AA6, AA7, and AA8 are L-amino acid residues; P is a hydrophobic residue; and Q is OH, NH2 or NRcRd. The invention further concerns processes for the manufacture of the novel peptide derivatives and the use of the compounds, and pharmaceutical compositions containing them, in treating MHC class II dependent T-cell mediated autoimmllne or inflammatory diseases, such as rheumatoid arthritis.
Patent DE-69731893-D1 (DE)
Inventor: VAN DER VEKEN GERMAINE
IPC: F03D1/04
Filed: 1997-10-21
Granted: 2005-01-13
Abstract: Wind engine device consisting of a wind power engine (2) and means (3) to increase the wind velocity in the direction of the wind power engine (2) when the wind velocities are low, whereby these means (3) contain at least a first wind guiding element (5) which narrows in a conical manner according to the direction in which the wind (W) blows towards the wind power engine (2), characterized in that this device (1) contains means (4) which make it possible to diminish the wind velocity, the wind force respectively, on the place where the wind power engine (2) is situated, which contain a second wind guiding element (9) which joins the exit (7) of the first element and which widens in a conical manner according to the direction in which the wind blows on the one hand, and adjustable means (10) to move the wind power engine (2) and the second wind guiding element (9) in relation to one another, such that the wind power engine (2) slides in further or less further in the second wind guiding element (9).
Patent DE-69739097-D1 (DE)
Inventor: WILLIAMS NIGEL EMLYN
IPC: G01C15/00
Filed: 1997-09-10
Granted: 2008-12-18
Abstract: A laser light referencing tool (100) comprises: laser means (314) for emitting a visible laser beam; portable power means (207, 208, 210) for powering the laser means; gravity-responsive directional means (300, 307, 208) for establishing a datum direction for the laser means; means (400, 404, 405) for attaching the tool to a generally vertical surface to be referenced; optical means (319) provided such that the visible laser beam is divergent in a single plane; and bearing means (206, 212) arranged such that when the tool is attached to the generally vertical surface by the attaching means (400, 404, 405), the gravity-responsive directional means (300, 307, 208) acts to establish the datum direction about the bearing means. The tool is arranged such that, in use, a line of light in the datum direction, or at a preset angle thereto, is projected by the laser means onto the generally vertical surface to which the tool is attached.
Patent DE-69803894-D1 (DE)
Inventor: GUILLAUMET GERALD
IPC: A61P25/28
Filed: 1998-04-23
Granted: 2002-03-28
Abstract: Benzodioxin and benzoxathiin derivatives of formula (I), their enantiomers, diastereoisomers, and salts with acids and bases are new: X, Y = S, O, CHq, CHSO or SO2, such that X, Y may not both be CHq; q = 0-2; Z = O or CH2; n = 0-4; A = -NR1R2 or a group -C(=T')NR6R7; R1 = H or 1-6C alkyl; R2 = -C(=T)R3; T = O or S; R3 = R'3 or -NR4R5; R'3 = H, 1-6C alkyl, 2-6C alkenyl, 1-6C alkynyl (sic), 3-8C cycloalkyl, cycloalkyl alkyl (all optionally substituted), or aryl or aralkyl; R4 = H or 1-6C alkyl; R5 = H, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, cycloalkyl, cycloalkyl alkyl (all optionally substituted) or aryl or arylalkyl; T' = O or S; R6 = H or 1-6C alkyl; R7 = H, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, cycloalkyl or cycloalkyl alkyl (all optionally substituted) or aryl or arylalkyl; R = H, 1-6C alkyl (optionally substituted), aryl or aralkyl; Ring A = optionally substituted by one or more halo, OH, 1-6C alkyl or alkoxy, CN, NO2, NH2 or trihaloalkyl; arylalkyl = 1-6C alkyl substituted by aryl; cycloalkyl alkyl = 1-6C alkyl substituted by 3-8C cycloalkyl; provided that when X, Z both = CH2, R = H, and A = NR1R2, then Y is not O; and when Z = O, n is not zero, and when Z = O and n = 1, then A is not CONEt2; when Z = CH2, n = 1, A = -NR1CSNR4R5, then R2 is not aryl; and when X = Y = O, the dotted lines in ring A are single bonds, R = H or CH2OH, then A is not NR1R2a; R2a = benzoyl (optionally substituted).
Patent DE-69806015-D1 (DE)
Inventor: SCHUMANN WERNER
IPC: C09B67/00
Filed: 1998-07-20
Granted: 2002-07-18
Abstract: Granular compacts (G) of a mixture of(A) at least one water-soluble dye or optical brightener, and(B) extender and, optionally,(C) at least one hydrophilic surfactant and/or(D) further additives, additionally containing(E) a dust-binding oil,are low-dust dry formulations of high bulk density which feature good dissolution, transportation and storage properties and are outstandingly suitable for the dyeing of the respective substrates.