baber/WOPTO huggingface dataset:
Patent EP-0568575-A1 (EP)
Title: Test et modele pour la maladie d'alzheimer
Inventor: HARDY JOHN ANTHONY
IPC: C12Q1/68
Filed: 1992-01-21
Abstract: Des systèmes servant de modèles pour la maladie d'Alzheimer comprennent une séquence d'ADN codant un fragment ou une isoforme de protéine précurseur d'amyloïde (APP) qui comprend une substitution d'acide aminé. L'acide aminé substitué dans la position d'acide aminé correspondant à la position de résidu d'acide aminé 717 d'APP 770 peut être autre que la valine. Des procédés servant à déterminer une prédisposition génétique à la maladie d'Alzheimer sont aussi décrits.
Patent EP-0542971-A1 (EP)
Inventor: MATHEWS LAWRENCE S
IPC: A61K39/395
Filed: 1992-05-08
Abstract: L'invention se rapporte à de nouvelles protéines réceptrices qui se caractérisent en ce qu'elles comportent, en partant de leur extrémité à terminaison N, les domaines suivants: un domaine de liaison de ligand, extracellulaire; un domaine trans-membrane, hydrophobe; et un domaine récepteur intracellulaire ayant une activité de type sérine kinase. Les récepteurs de cette invention peuvent en outre éventuellement comprendre un second domaine hydrophobe à leur terminaison amino. Ces protéines réceptrices se caractérisent en outre par le fait qu'elles présentent une affinité de liaison suffisante pour au moins l'un des éléments de la superfamille activine/FTC-beta des facteurs de croissance polypeptidiques, de sorte que des concentrations 10 nM de ce facteur de croissance polypeptidique occupe une proportion 50 % des sites de liaison de ces protéines réceptrices. Un élément préféré de cette superfamille de récepteurs se lie spécifiquement aux activines, de préférence aux inhibines, au facteur transformant de croissance-beta(FTC-beta), et à d'autres protéines du type non activine. Des séquences d'ADN codant pour ces récepteurs, des dosages utilisant ces récepteurs ainsi que des anticorps dérivés de ces récepteurs sont également décrits.
Patent EP-0626901-A1 (EP)
Title: Structures thermoplastiques moulees haut module recyclables renforcees a la fibre et leur procede de fabrication
Inventor: FISHER JOHN MICHAEL
IPC: C08J7/04
Filed: 1992-02-21
Abstract: L'invention concerne un procédé de préparation de structures composites renforcées recyclables présentant un fini de surface amélioré, qui consiste à chauffer une galette poreuse autoporeuse se composant d'un mélange intime homogène de fibres de renforcement haut module et de fibres agglomérées thermoplastiques à une température suffisante pour faire fondre le composé de résines et rendre la galette moulable, à placer ladite galette moulable dans un moule chauffé pour solidifier et pratiquement cristalliser le composé de résines, à introduire un enduit thermodurcissable contenant de la résine dans le moule, contre au moins une face de la structure cristallisée afin qu'au moins une face soit enduite, et à dégazer la structure enduite dans une moule pendant suffisamment de temps pour que l'enduit durcisse.
Patent EP-0587724-A1 (EP)
Inventor: STAUFFER CRAIG M
IPC: C23C16/455
Filed: 1992-05-29
Abstract: Module intégré (11) comportant un réservoir chauffé (44) servant à vaporiser le liquide utilisé pour le traitement de semi-conducteurs à l'aide de sources de liquide. Des vannes d'arrêt (20) ainsi qu'un limiteur proportionnel de pression (21) servant à réguler le flux de vapeur sortant du réservoir sont montés sur le module (11) de sorte que les vannes (20, 21) soient chauffées par simple conduction. Un manomètre de capacitance (19) également monté dans le module (11) comporte ses propres éléments chauffants (64A, 64B). Cet agencement permet d'éviter la condensation de la vapeur et d'obtenir des performances stables et une plus grande fiabilité.
Patent EP-0586573-A1 (EP)
Inventor: WAINWRIGHT NORMAN R
IPC: C12N15/12
Filed: 1992-05-15
Abstract: Protéines de liaisons/neutralisations d'endotoxine capables de lier une endotoxine in vivo, neutralisant ainsi l'effet toxique ou la bioactivité de l'endotoxine, lesquelles sont isolées d'une limule telle que la Limulus polyphemus, compositions pharmaceutiques et utilisations pharmaceutiques des protéines, procédé de purification desdites protéines et dosage pour endotoxine basés sur les protéines.
Patent EP-0619929-A1 (EP)
Inventor: WAKELAND CARL K
IPC: H04N9/75
Filed: 1992-06-30
Abstract: A method for merging first and second digital video signals generated by first and second video controllers, respectively, for merged transmission to a digital video decoder. The first video controller transmits the first digital video signal to the decoder while monitoring the signal to detect a luminance component which designates the boundary between a first image constructable from the first video signal and a second image constructable from the second video signal. When the luminance component is detected, a colorkey signal is generated by the first video controller and transmitted to the second video controller to initiate transmission of the second digital video signal to the decoder in place of the first digital video signal. The first video controller continues to monitor the first video signal until the absence of the luminance component is detected. The first video controller then transmits a second colorkey signal to the second video controller to terminate the second digital video signal and transmission of the first digital video signal to the decoder recommences.
Patent EP-0598749-A1 (EP)
Inventor: PORTNEY VALDEMAR
IPC: A61F2/16
Filed: 1992-07-09
Abstract: Système de lentilles ophtalmiques comprenant une lentille intra-oculaire (13a) adaptée à une implantation dans l'oeil (15a) ainsi que des lunettes (11a). La lentille intra-oculaire (13a) présente une partie de lentille intra-oculaire négative. Les lunettes (11a) comprennent un système à lentille positive destiné à orienter la lumière vers la partie de lentille négative de la lentille intra-oculaire (13a). Le système à lentille positive comprend une lentille positive (29) ainsi qu'une lentille négative (31) placée derrière ladite lentille positive (29).
Patent EP-0600926-A1 (EP)
Title: Weighing cell for an electronic balance.
Inventor: STAHL ALBRECHT
IPC: G01G7/06
Filed: 1992-07-24
Abstract: Described is a weighing cell for an electronic balance with two side walls (15, 16) which move parallel to each other as a function of the weight and in which are located two metal plates forming a condensor whose capacitance varies with the weight. One plate is a circuit board (17) which has a metal film (20) on the side facing the other plate (23) and which also carries the components (18, 19, 19') of the electric circuitry of the balance.
Patent EP-0597998-A1 (EP)
Inventor: COOK CHARLES R JR
IPC: F02D41/38
Filed: 1992-07-27
Abstract: Les circuits électroniques sont logés dans la rampe d'amenée de carburant et comprennent un agencement à microprocesseur permettant l'étalonnage dynamique de la rampe en usine sur toute sa plage de fonctionnement. La rampe est ensuite commandée par des données sérielles que lui transmet l'ordinateur de gestion du moteur.
Patent EP-0598010-A1 (EP)
Inventor: GALASSI CARLA
IPC: B24D15/00
Filed: 1992-07-24
Abstract: Patin en matériau souple et élastique servant au ponçage à la main de surfaces à l'aide de papier abrasif. Il possède un passage intérieur pour fluide communiquant avec l'extérieur par l'intermédiaire d'un manchon lui-même relié, par l'intermédiaire d'un tube, à une source de vide ou de fluide, ainsi qu'avec plusieurs trous traversant la face inférieure de traitement. Lorsqu'on emploie l'aspiration d'air, on a également prévu des évents menant jusqu'à l'extérieur et présentant une superficie de section moins grande que celle des trous d'aspiration. En outre, une chambre d'équilibrage du vide est formée dans ledit passage immédiatement après la mise en communication avec l'extérieur.
Patent EP-0600988-A1 (EP)
Inventor: SKONIECZNY JOSEPH P
IPC: G05D1/08
Filed: 1992-07-31
Abstract: Système (21) de commande de vol pour hélicoptère comportant une architecture de système de commande fondée sur un modèle qui fournit un signal coordinateur de commande de lacet au rotor arrière de l'hélicoptère afin de coordonner le vol de l'hélicoptère pendant un virage incliné. Ledit système de commande traite les informations provenant d'une série de capteurs (31) situés sur l'hélicoptère afin de fournir le signal de commande de lacet coordinateur sur une ligne de sortie (72) au rotor arrière (20) de l'hélicoptère.
Patent EP-0627130-A1 (EP)
Inventor: ROTH MICHAEL
IPC: H01R13/64
Filed: 1992-09-17
Abstract: Ce connecteur enfichable, composé d'une partie femelle en cuvette et d'une partie mâle enfichable dans la partie femelle et s'adaptant à celle-ci, possède dans chacune de ses zones terminales des nervures de sûreté qui donnent ensemble à la partie mâle une largeur supérieure au plus grand diamètre intérieur de la partie femelle. On évite ainsi un enfichage en biais et donc un endommagement des broches de connexion disposées dans la partie femelle.
Patent EP-0562088-A1 (EP)
Inventor: NILE JEFFERY G
IPC: A61B19/04
Filed: 1992-10-08
Abstract: There is disclosed a body contacting article, e.g. a surgeon's glove which comprises a first layer of a natural or synthetic elastomer and thereupon a layer of polymer comprising repeating units of the formula: [-CH2-CH(OR)-] and [-CH(CO2H)-CH(CO2R<1>)-] (I) or [-CH2-CH(R<4>)-] and [-CH(CO2H)-CH(CO2R<1>)-] (IA), wherein R is a lower alkyl group and R<1> is a lower alkyl group or a (lower) alkoxy (lower) alkyl group, and R<4> is hydrogen or a phenyl group.
Patent EP-0616696-A1 (EP)
Title: Gainage pour fibre optique
Inventor: STOCKMAN ANTHONY JOHN THE BLAC
IPC: G02B6/44
Filed: 1992-11-09
Abstract: Gainage pour fibres optiques et câbles de fibres optiques comprenant une longueur continue de tubulure, dont les parois sont conçues pour permettre de couder le tube selon un rayon prédéterminé et pour empêcher qu'il soit coudé selon un rayon inférieur au rayon prédéterminé. Les parois du tube (12) comprennent des parties (18) espacées les unes des autres lorsque le tube est droit, mais qui viennent en butée en (20) lorsque le tube est plié selon le rayon prédéterminé.
Patent EP-0617254-A1 (EP)
Inventor: COENEN WILFRIED DR ING
IPC: G01B11/06
Filed: 1993-03-25
Abstract: The invention relates to a method for determining the thickness of wheel rims or tyres on wheels of sets of railway wheels. In order to determine this thickness, it is proposed to illuminate the profile zones of the wheel which are relevant for a thickness to be determined, doing so by means of a light section or a light edge, and to use optical means to detect the light trace thereby produced. The trace is then digitised and the thickness is determined from the digitised values. In this case, the light edge is preferably to extend radially. <IMAGE>
Patent EP-0563984-A1 (EP)
Inventor: YABUSHITA YASUNORI
IPC: A61L33/00
Filed: 1993-04-02
Abstract: The antithrombotic intraocular lens of the present invention carries a fibrinolytic substance conjugatedly immobilized on its surface and, as such, lyses insoluble proteins such as fibrin deposited on the lens surface from the blood and exudate after implantation to fully retain its lens function. Furthermore, the present invention inhibits adhesion of the lens to the surrounding tissues and contributes to accelerated recovery after operation. The present invention further provides a simple method for immobilizing a fibrinolytic substance by conjugation on the surface of a variety of lens materials including silicones. Moreover, because the fibrinolytic substance is immobilized only to the surface of the lens material, the dynamic and optical properties of the intraocular lens are not adversely affected.
Patent EP-0569835-A1 (EP)
Inventor: LEOPARDI FRANCESCO
IPC: A61J1/05
Filed: 1993-05-05
Abstract: The invention relates to safety closing devices for containers of biological liquids and, particularly, for test tubes used for the drawing, transport and/or analysis of blood, of the type including an undercap and a cap, both made of a perforable material. 
     The undercap (2) and the cap (3) each include at least a central portion (4, 6), formed by one or more parts. 
     The central portion (4) of the undercap is sealingly locked by the front side on the edge (9) of the test tube (1) and the central portion (6) of the cap is sealingly locked on the side facing the undercap, by an axial pressure applied by locking means (13, 15; 14, 16), that can be only intentionally disengaged by an operator, and allow reciprocal mechanical coupling of the cap to the undercap and the assembly thereof onto the prearranged end (15) of the test tube.
Patent EP-0583564-A1 (EP)
Inventor: WINTER BEAT DR
IPC: C07C67/333
Filed: 1993-06-09
Abstract: The process consists of the isomerisation, using an acidic agent, of an epoxy ester of formula <IMAGE> in which R is used to denote a linear or branched lower C1-C6 alkyl radical and the wavy line defines a C-C bond of cis or trans configuration.
Patent EP-0591890-A1 (EP)
Title: Hand control system
Inventor: HEGG JEFFREY W
IPC: G05D1/00
Filed: 1993-10-04
Abstract: A servo controlled system is provided for electrically coupling the motions and applied forces of pilot and co-pilot control sticks (15, 55). Servo-coupling between the two control sticks is accomplished by detecting the position (17, 57) of the control sticks of respective controllers and/or detecting torque (101, 121) exerted on the control sticks. The position and torques signals are processed and employed in a feedback loop for each control stick to generate a feedback signal to motors (23, 63) to which the control sticks are mechanically coupled. The motors act on the control stick to simulate the feel of traditional mechanical controllers, and to cause the controllers to track each other's movements.
Patent EP-0590688-A1 (EP)
Inventor: ARONNE ARMAND J
IPC: B64D25/10
Filed: 1993-10-04
Abstract: Start-up electrical power modules (10) are utilized in electroballistic sequencing systems for initiating the ballistic sequence necessary for seat and canopy ejection in military aircraft. The power modules (10) utilize aircraft power to initiate the ballistic sequence necessary for ejection of the pilot or pilots. The power module (10) also comprises two independent internal power supplies (18,20) as back-up power sources in the event of total aircraft power failure. The power modules (10) are activated by the manual pulling action of an actuation shaft (22) by the pilot or by the automatic pushing action of the actuation shaft (22) by a piston once the pilot initiates the ejection sequence. Once the actuation shaft (22) is pulled into an armed position, dual switches (14,16) are activated thereby supplying electrical power from the aircraft or from the back-up power sources (18,20) to a signal conditioner and controller (12). The signal conditioner and controller (12) processes the signals and outputs a single direct current signal to a ballistic sequencer (52).
Patent EP-0594098-A1 (EP)
Inventor: LAZZARI GIANNI
IPC: G01H3/12
Filed: 1993-10-18
Abstract: A system is described for the detection and location of acoustic signals which can be used, for example, for the acquisition of voice messages or the like, in environments in which noises, echoes and reverberations are present. The system further enables an acoustic message (RS) cleared on the undesired components which are due to noises, echoes, etc. to be reconstructed. 
     In order to perform functions of this type, the system employs an array of microphones (P₀, P₁, P₂, P₃) and is based on the Fourier antitransform calculus of only the information of phases of the normalised cross power spectrum (Y₁, Y₂, Y₃) of pairs of signals (S₀, S₁, S₂, S₃), acquired from the microphones in the array (P₀, P₁, P₂, P₃).
Patent EP-0602473-A1 (EP)
Inventor: KLAUSING HELMUT DR
IPC: G01S13/90
Filed: 1993-12-03
Abstract: In a ROSAR apparatus, a comparator chip (11), in which imaging errors are found, is provided in the processor circuit for increasing and estimating the accuracy of resolution. This comparator chip acts on a chip (12) for correcting the range curvature error so that imaging errors are corrected. <IMAGE>
Patent EP-0578315-A1 (EP)
Inventor: SCHEFFEL KLAUS C O PHILIPS PAT
IPC: H04J3/00
Filed: 1993-07-01
Abstract: The invention concerns a synchronous transmission system with a circuit arrangement to determine the data bytes of a signal to be received or transmitted. This includes a control arrangement (2), which includes at least one counter (11) to mark the pointer bytes of each high bit-rate transport unit which may appear, and at least one counter (6) to mark the data bytes with a counter state of each high bit-rate transport unit which may appear. Also, the control arrangement (2) includes, for each group of low bit-rate transport units which may appear in each highest bit-rate transport unit which may appear, at least one position counter, which is provided to mark the data bytes with a counter state in a low bit-rate transport unit of the group. The control arrangement (2) is still provided at least for identification of the useful data bytes and pointer bytes, on the basis of the counter states and the information about the transport units of the signal. <IMAGE>
Patent EP-0604224-A1 (EP)
Inventor: HSIUNG HANSEN MAXWELL
IPC: C12N15/12
Filed: 1993-12-22
Abstract: The instant invention provides the porcine GRF receptor protein. The invention also provides DNA compounds encoding the pGRF receptor, recombinant DNA cloning and expression vectors comprising said DNA sequence, and recombinant host cells comprising said vectors. The invention also provides methods of making the pGRF receptor in recombinant and solid phase systems. The invention also provides methods of using the pGRF receptor in assay systems. The invention also provides methods of using said DNA sequences as probes to isolate and characterize GRF receptors and corresponding DNA sequences from other species.
Patent EP-0587459-A1 (EP)
Inventor: ELINGS VIRGIL B
IPC: G01B21/30
Filed: 1993-03-31
Abstract: An atomic force microscope in which a probe tip is oscillated at a resonant frequency and at amplitude setpoint and scanned across the surface of a sample in contact with the sample, so that the amplitude of oscillation of the probe is changed in relation to the topography of the surface of the sample. The setpoint amplitude of oscillation of the probe is greater than 10 nm to assure that the energy in the lever arm is much higher than that lost in each cycle by striking the sample surface, thereby to avoid sticking of the probe tip to the sample surface. Data is obtained based either on a control signal produced to maintain the established setpoint or directly as a function of changes in the amplitude of oscillation of the probe.
Patent EP-0591103-A1 (EP)
Inventor: KAESER ADOLF DR
IPC: C09B35/039
Filed: 1993-09-20
Abstract: The disazo dyes of the formulae (1), (2) and (3) listed in Claim 1 are particularly suitable for dyeing paper. Paper is dyed, using these dyes, in greenish yellow or yellow to red shades with good fastness properties.
Patent EP-0658420-A1 (EP)
Inventor: BONIFACI LUIGI
IPC: B65D65/40
Filed: 1993-12-16
Abstract: The present invention is a multilayer material for making packages adequate for containing dry materials, which exhibits a superior moisture protection and prevents the migration of greasy compounds through an ethylene vinyl alcohol copolymer barrier layer. This migration, beyond leading to stains and poor aesthetics, can jeopardize the strength of the package container. The multilayer material of the present invention is glued together for reforming into a packaging container, and not, as more commonly, heat sealed. To achieve this aim, the EVOH layer is sandwiched in between two layers of cardboard or paper. In this way the cardboard or paper layers of this multilayer material constitute the outermost layers. In reforming said multilayer material into a packaging container, starting from a single blank, the inner part of said container, made of cardboard or paper, can now be glued onto the outer part of said container, also made of cardboard or paper. The present invention does not need therefore more sophisticated assembling techniques, such as for example heat sealing, for the reforming into a packaging carton.
Patent EP-0564445-A1 (EP)
Inventor: RITTER KLAUS DIPL-ING
IPC: B21F23/00
Filed: 1993-04-01
Abstract: Device for the alternate feeding of different lengths of material from a supply of material to a processing installation, with a threading device (5) which can be swivelled out of a pick-up position by means of a working cylinder (15) into an insertion position determined by the working line (L) of the processing installation, the said threading device being provided with a feed roller which can be driven in both directions of rotation and with a contact-pressure roller which can be moved relative to the feed roller and is intended to press on the forward end of the length of material, with a clamping turret (7) which can be pivoted about a horizontal pivot axis (8) by means of a pivoting drive (22, 23, 24) and is provided with a plurality of clamping devices (27, 28, 29, 30, 31, 32) arranged on a circular arc around the pivot axis and intended to accept the forward end (E) of in each case one length of material from the threading device in the working line (L), and with a straightening unit arranged in the working line on the output side of the threading device and the clamping turret and having at least one straightening device with adjustable straightening rollers. <IMAGE>
Patent EP-0630414-A1 (EP)
Inventor: TRENT JEFFREY M
IPC: C12Q1/68
Filed: 1992-12-03
Abstract: The present invention provides rapid, reproducible procedures for generating chromosome region-specific probes (CRSPs) for diagnostic and research applications. Region-specific probes are provided by direct in vitro enzymatic amplification (PCR) of microdissected chromosomal or hybridized DNA from the chromosomal region of interest, followed by labelling for in situ hybridization to metaphase chromosomes and interphase nuclei. CRSP specificity can be further enhanced using a linker-based strategy, wherein linkered DNA (LDNA) sequences prepared from DNA libraries are hybridized to chromosomal DNA in situ, microdissected from the chromosomal region of interest and then directly amplified using the linker as primer. These procedures make it possible to generate a vast number of chromosome region-specific probes without microchemical manipulation after dissection and provide means for identifying cryptic chromosomal alterations previously not amenable to routine cytogenetic analysis. Probes generated by the methods of the present invention can also be used for screening any DNA library of interest.
Patent EP-0627218-A1 (EP)
Inventor: NAKAMICHI KOUICHI
IPC: A61K9/00
Filed: 1993-02-17
Abstract: Comprimé se dissolvant rapidement dans la cavité buccale, pouvant être réalisé simplement, sans avoir recours à une technique d'élaboration spéciale. Le comprimé renferme un alcool de sucre ou une matière analogue en tant qu'ingrédient principal. Il est réalisé par cristallisation en milieu humide, le mélange malaxé d'alcool de sucre ou de substance analogue étant mêlé à la substance active par moulage sous pression avant séchage. Ce comprimé peut être réalisé simplement par modification partielle du procédé classique et présente une stabilité physico-chimique satisfaisante.
Patent EP-0590109-A1 (EP)
Title: PRE-CIBLAGE DE PAIRE DE LIAISON $i(IN VIVO)
Inventor: POMATO NICHOLAS
IPC: A61K49/00
Filed: 1993-03-03
Abstract: Méthode de ciblage in vivo chez un patient d'une fraction fonctionnelle par administration d'une fraction de ciblage couplée à un composant d'affinité, de sorte que la fraction de ciblage ait une affinité pour les sites de liaison de la zone cible, et par administration d'un partenaire de liaison au composant d'affinité couplé à une fraction fonctionnelle de manière à localiser la fraction fonctionnelle dans la zone cible. De préférence, pour la réalisation d'une imagerie ou d'une thérapie in vivo, la fraction de ciblage est un anticorps et la fraction fonctionnelle est un radioélément. Le composant d'affinité peut être un nouvel analogue de méthotréxate.