baber/WOPTO huggingface dataset:
Patent JP-2023120165-A (JP)
Title: Heat exchanger module, method of manufacturing heat exchanger module, and pipe type heat exchanger with heat exchanger module
Inventor: YVES DE VOS
IPC: F28D7/16
Filed: 2023-02-15
Abstract: To provide a heat exchanger module and a pipe type heat exchanger with the module suitable to high-pressure use, especially, pressure use of fluid pressure of up to hundreds of bar.SOLUTION: A heat exchanger module 1 comprises several U-shaped pipes 30 for first fluid flow, and the U-shaped pipe 30 has two straight sections 31 and 35 connected by a U-shaped part 32. Entrance ends 33 of several U-shaped pipes 30 are connected to an entrance collector pipe 20, and exit ends 34 of several U-shaped pipes 30 are connected to an exit collector pipe 21. The two straight sections 31 and 35 of the U-shaped pipe 30 have different lengths so that a length axis of the entrance collector pipe 20 and a length axis of the exit collector pipe 21 are placed at mutually different heights with respect to the height of the heat exchanger module 1. There are also provided a method of manufacturing the heat exchanger module 1 and a pipe type heat exchanger with a plurality of heat exchanger modules 1.SELECTED DRAWING: Figure 1
Patent JP-2023057176-A (JP)
Title: Sole and shoe
IPC: A43B13/18
Filed: 2023-02-22
Abstract: PROBLEM TO BE SOLVED: To provide a sole for a shoe, in particular for a sports shoe, with a midsole. 
     SOLUTION: The midsole includes a first sole region, which includes particle foam. The midsole further includes a deformation region within the midsole, where the deformation region has a volume greater than that of a single expanded particle and is positioned to allow a sideward deformation of material of the first sole region under a pressure load on the sole. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023143761-A (JP)
Title: display device
Inventor: SASAKI TOMOO
IPC: G02F1/1345
Filed: 2023-03-01
Abstract: To solve an issue that an operator cannot see a connector when the operator is doing a connection work of a flexible flat cable in a configuration in which a color filter substrate is arranged closer to a backlight side than an active matrix substrate is and this causes reduction of the work efficiency.SOLUTION: In a display device, a flexible flat cable (1) for connecting a first circuit board (DA) and a second circuit substrate (TC) to each other is bent at more than one bending position so that the back surface of the cable in a first end faces a backlight side and the front surface of the cable in a second end faces a backlight side. The first end is connected to a first connector (KA) of the first circuit board and the second end is connected to a second connector (CB) of the second circuit board.SELECTED DRAWING: Figure 7
Patent JP-2023131162-A (JP)
Title: Systems and methods for robotic system with object handling
Inventor: FLORIS GAISSER
IPC: G06T7/11
Filed: 2023-03-08
Abstract: To provide a computing system designed to identify pickable regions of objects from among a group of objects.SOLUTION: The computing system includes at least one processing circuit configured to identify pickable regions of objects according to image information of the objects. Pickable regions are determined according to a surface cost map, indicating smoothness of regions of the image information, determined according to height differences and normal differences. Identification of pickable regions is used in a motion planning operation to transfer the objects.SELECTED DRAWING: Figure 4
Patent JP-2023152874-A (JP)
Title: Preparation method of liquid composition for solid electrolyte membrane formation, liquid composition for solid electrolyte membrane formation, and production method of solid electrolyte membrane
Inventor: DOI TOSHIHIRO
IPC: H01L21/316
Filed: 2023-03-24
Abstract: To provide a liquid composition for forming a solid electrolyte membrane consisting of oxides containing lanthanum and zirconium which does not specifically require an acid as a solvent, a preparation method thereof, and a production method of a solid electrolyte membrane.SOLUTION: In the preparation method of a liquid composition for solid electrolyte membrane formation, a mixture containing a long-chain carboxylate of a rare earth element and an alkoxide of zirconium or tantalum is refluxed in the presence of a carboxylic acid ester.SELECTED DRAWING: Figure 1
Patent JP-2023155188-A (JP)
Title: power conversion system
Inventor: LIU WEI-LIN
IPC: H02J3/46
Filed: 2023-03-31
Abstract: To provide a power conversion system in which a micro control unit acquires the current charge rate of a rechargeable battery on the basis of a charge state signal and acquires the external output power of the power conversion system on the basis of the voltage and current detected by a voltage and current meter.SOLUTION: When a micro control unit detects an occurrence of an off-grid of a commercial power supply, the micro control unit adjusts the frequency of AC power output by a power conversion system and switches the frequency of the AC power between three or more different frequencies on the basis of the external output power and the current charge rate of the rechargeable battery. As the current charge rate of the rechargeable battery increases, the frequency of the AC power is switched to a lower frequency.SELECTED DRAWING: Figure 2
Patent JP-2023085487-A (JP)
Title: sensor assembly
Inventor: SASCHA LUTZ
IPC: G01N27/28
Filed: 2023-04-06
Abstract: To provide an extracorporeal diagnostic sensor assembly having a plurality of parameters, quick without interference and capable of giving reliable results using a small sample volume.SOLUTION: A sensor assembly 1 consists of: two substrates 10A and 10B facing each other and including fluid conduits 2 and 4 for receiving a sample; and an electrochemical sensor including electrodes arranged on the two substrates 10A and 10B facing each other. A counter electrode 11C and reference electrodes 11B and 12B are formed on the substrate 10B; work electrodes 11A and 12A are formed on the substrate 10A; and thereby, a sensor assembly having simple geometry and a small size can achieve optimal sensor operation conditions in homogeneous and symmetrical electric field density.SELECTED DRAWING: Figure 1
Patent JP-2023082209-A (JP)
Title: Anti-obesity agent and food composition for prevention or treatment of obesity
Inventor: KIYOSE CHIKAKO
IPC: A23L33/105
Filed: 2023-04-06
Abstract: To provide a safe anti-obesity agent that can be taken daily, has no risk of side effect, and can be expected to have an excellent effect.SOLUTION: The problem is solved by an anti-obesity agent containing a ground product or extract of basil or coriander. The anti-obesity agent can be used to prevent or treat obesity.SELECTED DRAWING: None
Patent JP-2023089191-A (JP)
Title: Factor h potentiating antibodies and uses thereof
Inventor: TACO WILLEM KUIJPERS
IPC: A61P13/12
Filed: 2023-04-17
Abstract: To provide novel and improved therapeutic agents that bind to FH, useful in the treatment of disorders associated with unwanted or excessive complement activation.SOLUTION: The invention relates to novel, isolated, synthesized or recombinant antibodies or fragments thereof specific for factor H. The invention further relates to the use of such antibodies or fragments for inhibiting complement activation and treatment of disorders associated with complement activation.SELECTED DRAWING: None
Patent JP-2023103259-A (JP)
Title: Information processing device, data synchronization program, data synchronization method, data synchronization system, and terminal device
Inventor: AOKI KENGO
IPC: H04L67/1095
Filed: 2023-04-20
Abstract: To provide an information processing device, a data synchronization program, a data synchronization method, a data synchronization system, and a terminal device that suppress an increase in processing load and communication load in a situation that data of a plurality of user terminals are synchronized.SOLUTION: A server device 1 is connected, via a network, to a plurality of clients participating in a virtual space where a synchronization target object is to be synchronized between clients in a synchronization group consisting of clients who have ownership of the object and clients who do not have the ownership of the object. The server device comprises: data reception means 104 configured to receive a difference from the synchronization target object from the client having the ownership of the object; data update means 107 configured to update a plurality of replicas obtained by replicating the synchronization target object by using the difference and stored in a memory 12; and data transmission means 105 configured to transmit the difference to a client other than the client having the ownership among the plurality of clients.SELECTED DRAWING: Figure 3
Patent JP-2023099092-A (JP)
Title: Cargo loaded extracellular vesicles
Inventor: SHI JIAHAI
IPC: A61P35/02
Filed: 2023-04-27
Abstract: To provide stable extracellular vesicles for therapeutic or diagnostic purpose.SOLUTION: The application relates to extracellular vesicles derived from red blood cells and particularly, although not exclusively, extracellular vesicles derived from red blood cells containing a cargo. The cargo may comprise small molecules, proteins, nucleic acids or components of the CRISPR/Cas9 gene editing system. The extracellular vesicles derived from red blood cells may be used in the treatment of medical disorders such as a genetic disorder, inflammatory disease, cancer, autoimmune disorder, cardiovascular disease or a gastrointestinal disease. Also provided is a method for loading the cargo into the extracellular vesicles derived from red blood cells by electroporation.SELECTED DRAWING: None
Patent JP-2023095928-A (JP)
Title: Use of ezh2 inhibitors for treating cancer
Inventor: SCOTT DAIGLE
IPC: A61P37/04
Filed: 2023-04-28
Abstract: To provide methods of treating, identifying and/or selecting for treatment of a subject having a cancer in which an immune checkpoint protein is upregulated.SOLUTION: In certain embodiments, the methods for treating cancer in a subject in need thereof comprise administering, to the subject, (a) a therapeutically effective amount of an EZH2 inhibitor and (b) a therapeutically effective amount of an immune checkpoint inhibitor. In certain embodiments of the methods of the disclosure, the EZH2 inhibitor is tazemetostat.SELECTED DRAWING: None
Patent JP-2023093750-A (JP)
Title: game machine
Inventor: ICHIHARA TAKAAKI
IPC: A63F7/02
Filed: 2023-05-02
Abstract: To provide a game machine capable of further increasing game interest.SOLUTION: Light emission control means includes: first rainbow control execution means for executing first rainbow control that causes a plurality of light emitting units to emit light in a rainbow mode by satisfying a predetermined condition to which a profit is given; and second rainbow control execution means for executing second rainbow control that causes the plurality of light emitting units to emit light in the rainbow mode by satisfying a condition to which a profit is not given, different from a predetermined condition. When brightness adjustment operation is performed during the first rainbow control, the brightness can be adjusted while the plurality of light emitting units emit light in the rainbow mode, whereas when the brightness adjustment operation is performed during the second rainbow control, the brightness cannot be adjusted in a state where the plurality of light emitting units emit light in the rainbow mode.SELECTED DRAWING: Figure 198
Patent JP-2023106461-A (JP)
Title: flower picking method
Inventor: CHANG IN KOOK
IPC: A01G7/06
Filed: 2023-05-10
Abstract: To provide a flower picking method safe for bees.SOLUTION: A flower picking method for spraying a flower picking composition that is safe for bees at the time of spraying, the alcohol concentration in the flower picking composition is more than 0.2% (V/V) and equal to or less than 0.8% (V/V) when sprayed. The flower picking composition contains one or more kinds selected from C6 to C12 fatty alcohol, or one or more kinds selected from C10 to C18 aliphatic alcohol having one or more double bonds, and one or more kinds of emulsifiers. The C6 to C12 fatty alcohol is 1-hexanol, 1-heptanol, 1-octanol, 1-nonanol, 1-decanol, 1-undecanol, 1-dodecanol, 2-ethyl-1-hexanol, or cyclohexanol. the C10 to C18 aliphatic alcohol having one or more double bonds is oleyl alcohol. The alcohol concentration is 0.01 vol% to 0.8 vol%.SELECTED DRAWING: None
Patent JP-2023091076-A (JP)
Title: game machine
Inventor: WATANABE KAZUTERU
IPC: A63F7/02
Filed: 2023-05-15
Abstract: To provide a game machine capable of enhancing interest in a game.SOLUTION: A Pachinko machine 10 having a so-called limiting function for always setting a jackpot probability of a special pattern to a low-probability state each time when a predetermined number of jackpots occur is configured such that a "setting suggestive performance" is easily won as the number of winning times of a jackpot type disadvantageous to a player approaches the number of limit times. Also, the Pachinko machine 10 is configured so as to more concretely and easily suggest a winning probability of a lottery for executing a "setting suggestive performance" and contents of a probability setting value of the Pachinko machine 10 in the "setting suggestive performance" by winning a jackpot again in a situation in which a hold-back jackpot is won during a hold-back period.SELECTED DRAWING: Figure 8
Patent JP-2023103467-A (JP)
Title: Scaffold loading and delivery systems
Inventor: MARC HELMICK
IPC: A61F2/966
Filed: 2023-05-24
Abstract: To provide materials, devices, kits and methods that may be used for loading scaffolds into delivery devices and for delivery of scaffolds into the body of a patient, including delivery of scaffolds to the paranasal sinuses for treatment of chronic sinusitis, among other purposes.SOLUTION: Scaffold delivery systems are provided, which are useful for the loading and/or delivery of self-expanding scaffolds 420 that comprise a scaffold wall and have a scaffold lumen, a proximal scaffold end, a distal scaffold end, an inner luminal surface, and an outer abluminal surface.SELECTED DRAWING: Figure 4
Patent JP-2023120263-A (JP)
Title: exercise treadmill
Inventor: ROGER BATES
IPC: A63B22/02
Filed: 2023-06-12
Abstract: To provide techniques that help a user to coordinate treadmill handlebars gripping locations with desired intensity and/or step length.SOLUTION: A treadmill 100 has a front or rear set of first pulleys, and a looped belt. The pulleys are mounted on a roller tube rotating with the pulleys. An opposite end of the treadmill may have a second set of pulleys to support the belt. The roller tube is mounted on a stationary shaft using bearings on each side and a one-way device, e.g., a sprag clutch, that allows the pulleys to rotate in one direction. The rotation direction corresponds to the movement of the top of the belt from the front to the rear of the treadmill. The one-way device prevents the pulleys from rotating in the opposite direction, preventing the top of the belt from moving from the rear of the treadmill to the front.SELECTED DRAWING: Figure 4
Patent JP-2023107911-A (JP)
Title: Beer taste beverage, method for producing beer taste beverage, and method for improving sharpness of odd taste derived from barley/wheat in beer taste beverage
Inventor: SHINKAI TETSURO
IPC: C12C7/04
Filed: 2023-06-13
Abstract: To provide a beer taste beverage with a reduced carbohydrate content, in which the proportion of malt in the raw material is 50 mass% or more, however the sharpness of odd taste derived from barley/wheat is improved.SOLUTION: The present invention provides a beer taste beverage in which: the proportion of malt in the raw material is 50 mass% or more, the raw material including saccharides, and the carbohydrate content of the beer taste beverage is 1.0 g/100 ml or less.SELECTED DRAWING: None
Patent JP-2023184483-A (JP)
Title: 半導体基板の製造方法
IPC: H01L21/304
Filed: 2023-06-14
Abstract: 【課題】一態様において、接着剤の除去性に優れる洗浄剤組成物を用いた半導体基板の製造方法を提供する。【解決手段】本開示は、（１）ウエハを固定部材に接着剤で接着する工程と、（２）ウエハの固定部材との接着面の裏面を研磨する工程と、（３）ウエハの研磨された面を加工する工程と、（４）加工されたウエハと固定部材とを分離する工程と、（５）分離されたウエハに残留する接着剤を洗浄剤で除去する工程とを含む半導体基板の製造方法であって、前記工程（３）は、固定部材に接着剤で固定されたウエハを２３０℃以上の温度で加熱処理することを含み、前記工程（５）で用いる前記洗浄剤が、アルカノールアミン（成分Ａ）と下記式（Ｉ）で表されるグリコールエーテル（成分Ｂ）とを含有し、成分Ａの含有量が３５質量％以上８５質量％以下である洗浄剤組成物である、半導体基板の製造方法に関する。Ｒ－Ｏ－（ＥＯ）ｎ－Ｈ （Ｉ）【選択図】なし
Patent JP-2023115199-A (JP)
Title: game machine
Inventor: KAWAZOE TOMOHISA
IPC: A63F7/02
Filed: 2023-06-27
Abstract: To increase interest of a game.SOLUTION: A game machine having illumination on the outer frame may or may not execute a specific performance during a winning game. When the specific performance is executed, the illumination mode of illumination on the outer frame after the game is different from that in the case where specific performance is not executed.SELECTED DRAWING: Figure 66
Patent JP-2023139019-A (JP)
Title: Battery, manufacturing method thereof, metal terminal with adhesive film for metal terminal, and winding body for the adhesive film for metal terminal
Inventor: NAGAI ATSUSHI
IPC: H01M50/178
Filed: 2023-07-04
Abstract: To provide a battery appropriately suppressing opening of a packaging material in a portion, where an adhesive film is positioned, even in a case where an internal pressure of the battery rises.SOLUTION: The present invention relates to a battery comprising at least: a battery element including a cathode, an anode and an electrolyte; a packaging material sealing the battery element; and a metal terminal respectively electrically connected to the cathode and the anode and extending outside the packaging material. In the battery, an adhesive film for metal terminal is disposed between the metal terminal and the packaging material. The adhesive film for metal terminal successively comprises a first polyolefin layer, a substrate film containing polyethylene-naphthalate, and a second polyolefin layer. At least one of the first polyolefin layer and the second polyolefin layer contains acid-modified polyolefin. An angle θ formed from a direction Ymax which is a maximum intra-plane orientation direction of a naphthalene ring contained in the substrate film and a direction in which the metal terminal extends outside the packaging material is 45° or more and 135° or less.SELECTED DRAWING: None
Patent JP-2023153780-A (JP)
Title: Food products comprising milk proteins and non-animal proteins, and methods of producing the same
Inventor: Timothy Geistlinger
IPC: A23C11/06
Filed: 2023-07-07
Abstract: To provide food products which comprise milk proteins and non-animal proteins and have attributes identical or superior to milk and/or its derivative dairy products.SOLUTION: A dairy-like food product comprises: a single type of milk protein consisting of a recombinant β-lactoglobulin; one or more native and/or recombinant non-animal proteins and/or hydrolyzed non-animal proteins; and lactic acid bacteria; where i) the food product is essentially free of any milk protein other than the single type of milk protein consisting of a recombinant β-lactoglobulin, and ii) the recombinant β-lactoglobulin imparts a texture or taste of a dairy product to the food product. The dairy-like food product has a pH less than 7.SELECTED DRAWING: None
Patent JP-2023126643-A (JP)
Title: Optical transmission subassembly
Inventor: NAKAI YOSHIHIRO
IPC: G02F1/01
Filed: 2023-07-21
Abstract: To stabilize the characteristics of a modulator with a simple configuration.SOLUTION: Drive voltage VDD is divided into first voltage V1 applied to an optical modulator 30 and second voltage V2 applied to a transistor 42. Current ID is determined according to a control signal CS inputted to a first terminal 42a. The first voltage V1 is determined according to the characteristics of the optical modulator 30 on the basis of current Iph. Second voltage V2 changes corresponding to the first voltage V1. A submount 34 includes a signal line 44, a ground pattern 36 and a pad 46. The optical modulator 30 includes a first electrode 30p and a second electrode 30n. The first terminal 42a is directly connected to the signal line 44. A third terminal 42c is directly connected to the ground pattern 36. A second terminal 42b is directly connected to the pad 46. The pad 46 and the first electrode 30p are connected with a first wire W8 to each other.SELECTED DRAWING: Figure 4
Patent JP-2023153999-A (JP)
Title: Game machine
Inventor: TERAO KAZUMA
IPC: A63F5/04
Filed: 2023-08-09
Abstract: To make a player select an execution frequency of a pseudo game performance.SOLUTION: A game machine comprises a start switch, and can execute a pseudo game performance for temporarily stopping a reel on the basis of an operation of a stop switch. When a selection condition of the pseudo game performance is satisfied ([Yes] in a step S3032), a game progresses to a step S3033, and outputs a selection screen of an execution frequency of the pseudo game performance. In this state, a player is made to operate the start switch. When the start switch is operated ([Yes] in a step S3034), the game progresses to a step S3035, and the execution frequency of the pseudo game performance corresponding to the selection screen at the moment at which the start switch is operated is set.SELECTED DRAWING: Figure 438
Patent JP-2023171477-A (JP)
Title: 動脈系の機能性を測定するための装置
IPC: A61B5/022
Filed: 2023-10-04
Abstract: 【課題】血圧を測定し、および／または、内皮機能不全の徴候を得るための、使い方の易しい、動脈系の機能性を測定するための装置を提供する。【解決手段】個人の動脈系の機能性を測定するための装置は、動脈系に対して、４７５ｎｍから６００ｎｍの範囲の波長を有する電磁放射を出射し、動脈系から反射された電磁放射の一部を受信するためのフォトプレチスモグラフィセンサ（１０１）を備えている。装置は更に、フォトプレチスモグラフィセンサが電磁放射を動脈系に出射し、電磁放射を動脈系から受信するときに、動脈系に印加される機械的圧力を管理するための圧力装置（１０２）を備えている。反射された電磁放射の包絡線上の機械的圧力の結果は、動脈の拡張期血圧を決定するために、または、正常な内皮機能があるかどうかを決定するために使用できる。【選択図】図１ａ
Patent JP-2024001173-A (JP)
Title: 培養容器及び培養方法
IPC: C12M3/00
Filed: 2023-10-05
Abstract: 【課題】細胞等が培養容器に接着しやすく、細胞等の機能を正常に維持できる培養容器、及び培養方法を提供する。【解決手段】培養容器が、底面部材と、側壁部材とを有し、底面部材と側壁部材とが接合することで少なくとも一つの培養空間が形成され、底面部材の少なくとも一部が、少なくとも酸素透過層（Ｉ－ｂ）と、ガスバリア層（ＩＩ－ｂ）とを有し、ガスバリア層（ＩＩ－ｂ）が、酸素透過層（Ｉ－ｂ）の下に、酸素透過層（Ｉ－ｂ）から着脱可能に重ねられ、ガスバリア層（ＩＩ－ｂ）が、下記要件（５）を満たし、酸素透過層（Ｉ－ｂ）が、下記要件（６）を満たす。（５）温度２３℃、湿度０％の時の酸素透過度Ｐ（ＩＩ－ｂ）が３０００ｃｍ３／（ｍ２×２４ｈ×ａｔｍ）以下である（６）温度２３℃、湿度０％の時の酸素透過度Ｐ（Ｉ－ｂ）が前記Ｐ（ＩＩ－ｂ）の６．０倍以上である【選択図】図１
Patent JP-2023175932-A (JP)
Title: 遊技機
IPC: A63F7/02
Filed: 2023-10-05
Abstract: 【課題】興趣性が高い演出を実行可能な遊技機を提供すること。【解決手段】遊技機１では、大当たりに対する信頼度を示唆する複数の信頼度示唆演出を実行することが可能である。信頼度示唆演出には、例えば、第１態様の装飾図柄を表示しているときに実行可能な演出と、第２態様の装飾図柄を表示しているときに実行可能な演出とがある。第１態様の装飾図柄を表示しているときに実行可能な信頼度示唆演出には、例えば、保留アイコン変化演出、当該アイコン変化演出、擬似連演出、操作促進演出、背景演出、チャンス目演出、図柄変化演出等がある。また、第２態様の装飾図柄を表示しているときに実行可能な信頼度示唆演出には、例えば、当該アイコン変化演出、タイトル表示、操作促進演出、カットイン等がある。【選択図】図７
Patent JP-2024009946-A (JP)
Title: 抗ｐｄ－１抗体と他の抗体の組み合わせを含む組成物
IPC: A61K39/395
Filed: 2023-10-12
Abstract: 【課題】免疫チェックポイント抗体と第二抗体の組み合わせを含む医薬組成物を提供する。【解決手段】本発明は、第一抗体および第二抗体である抗癌剤の組み合わせを含む、医薬組成物を提供する。ある態様において、第一抗体は抗プログラム死－１(ＰＤ－１)抗体である。ある態様において、組成物は用量比固定製剤である。ある態様において、組成物を均一用量として投与する。疾患を有する対象を処置するためのキットもまた開示され、キットは、ここに開示する組成物の何れかの一定用量および疾患の処置のための本発明方法の何れかにおいて組成物を使用するための指示を含む。【選択図】なし
Patent JP-2023532377-A (JP)
Title: 医療用内視鏡プランジャ
IPC: A61B1/015
Filed: 2021-07-07
Abstract: 本発明は、前面の１つに開口する少なくとも部分的に中空の中央流路を有する中央ロッド（４０）と、流体ダクトに接続するためのシートを画定するヘッドとからなり、ヘッド（４１）及びチャネル（４０）は、弾性的手段によって接合される滅菌可能な医療内視鏡プランジャに関し、アセンブリは、可撓性の弾性ポリマーで作られる一体構造の単一部品からなることを特徴とする。
Patent JP-2023537215-A (JP)
Title: 無細胞核酸についてのヌクレアーゼに関連する末端シグネチャ分析
IPC: C12Q1/6883
Filed: 2021-07-13
Abstract: 無細胞ＤＮＡ末端シグネチャ／モチーフ及びＤＮＡ鎖間のオーバーハングのサイズに影響を与える組織におけるヌクレアーゼ発現を使用して、様々な実施形態が実施される。実施形態は、正常細胞と比較して異常細胞において異なって調節されるヌクレアーゼを同定することができる。実施形態は、ヌクレアーゼが、（ｉ）特定の配列末端シグネチャ、又は（ｉｉ）第１の鎖と第２の鎖との間に指定された長さのオーバーハングを有するＤＮＡ分子へと、ＤＮＡを優先的に切断することを決定することができる。パラメータは、特定の配列末端シグネチャに対応する末端配列を含むＤＮＡ分子の量及び／又は指定された長さのオーバーハングに正確に相関する測定された特性に基づいて、生物学的試料について決定することができる。このパラメータを使用して、組織タイプの特徴、臨床的に関連するＤＮＡ分子の画分濃度、又は生物学的試料中の組織タイプの異常レベルを決定することができる。【選択図】なし
Patent JP-2023533841-A (JP)
Title: プラズマ支援加工装置用の電圧波形発生器
IPC: H05H1/46
Filed: 2021-07-06
Abstract: プラズマ支援加工装置用の電圧波形発生器は、共通ノードと、第１のスイッチノードにおいて少なくとも２つの電圧レベルを切り替えるように動作可能な電圧供給回路と、第１のスイッチノードと共通ノードとの間に接続された第１のインダクタと、電圧供給回路を動作させるように構成された制御ユニットとを備える。