baber/WOPTO huggingface dataset:
Patent EP-0778049-B1 (EP)
Inventor: PLICCHI GIANNI
IPC: A61N1/365
Filed: 1996-12-03
Granted: 2004-02-18
Abstract: The adaptive heart pacemaker (H) described is characterized by the specialized use of a movement sensor to identify the patient's step frequency and the type of ambulation in order to determine the heart-stimulation frequency. The movement sensor may be constituted by an accelerometer (100) operating in the 0.1-100 Hz band and located inside the casing in mechanical continuity with metal walls thereof so as to permit transmission and hence detection both of inertial accelerations due to the patient's movement and of vibrations transmitted by the human body to the casing generally within the frequency band indicated above. The signal generated by the sensor (100) is amplified and filtered in two different frequency bands in order to select two components relating to inertial accelerations (200) in the 1-5 Hz range and relating to vibrations (300) in the 20-50 Hz band, respectively, these components being transmitted to different logic analysis units. These units perform a complex time discrimination of each individual signal and of their interaction, effectively identifying steps and eliminating artifacts as well as recognizing certain types of ambulation such as running and going down stairs. The data obtained relating to the step frequency and type of ambulation enable the stimulation frequency of the heart pacemaker in the atrium, in the ventricle, or in both, to be determined by means of programmable algorithms held in the control unit (CS) of the pacemaker. <IMAGE>
Patent EP-0727228-B1 (EP)
Inventor: COLIN BRUNO
IPC: G01N35/10
Filed: 1996-02-09
Granted: 2002-04-24
Abstract: For decontamination of a pipette type needle system, an electrically heated hollow needle (2) has a metal tube (3) in contact with the contaminated matter at its interior and/or exterior. Electrical energy is applied to the needle (2) at a level according to the electrical characteristics of the tube (3). This is determined in order to develop the heat needed to decontaminate the interior and exterior of the needle, without affecting its shape or structure. Also claimed is a needle (2) assembly with a hollow metal tube (3) with an active free end (3a) and another inactive end (3b). The intermediate tube section (3c) can be contaminated and decontaminated a number of times. An electrical connection (5) gives a current circuit with the needle (2) at the active (3a) and inactive (3b) ends. The control (4) sets the level of electrical energy applied to the needle (2).
Patent EP-0815325-B1 (EP)
Inventor: JERATH VIJAY
IPC: E01B31/12
Filed: 1996-03-01
Granted: 2002-07-31
Abstract: A steel rail comprising a plurality of individual rails welded together with any resulting excess material removed from the rail by a stripping process. The weld sites of the rail may be subjected to natural air and/or independent accelerated cooling and grinding or other surface material removal technique and/or peening process.
Patent EP-0871654-B1 (EP)
Inventor: LEHRER ROBERT I
IPC: A01N63/50
Filed: 1996-05-24
Granted: 2003-04-23
Abstract: Peptide-based compounds containing four invariant cycteine residues which have been optionally oxidized to contain two intramolecular disulfide bonds, or modified forms where the cysteines are replaced are useful as preservatives and in preventing, treating, or ameliorating viral or microbial infection in animals and plants, and in inactivating endotoxin. These compounds, in one embodiment, are of the formula:   A1A2A3A4A5C6A7C8A9A10 (1)   A11A12C13A14C15A16(A17A18)  and the N-terminal acylated and/or C-terminal amidated or esterified forms thereof, which is either in the optionally -SH stabilized linear or in a cystine-bridged form wherein each of A1 and A9 is independently a basic amino acid; each of A2 and A3 is independently a small amino acid; each of A5, A7, A12, A14 and A16 is independently a hydrophobic amino acid; A4 is a basic or a small amino acid; A10 is a basic or a small amino acid or is proline; A11 is a basic or a hydrophobic amino acid; A17 is not present or, if present, is a small amino acid; A18, is not present or, if present, is a basic amino acid; or a modified form of formula (1) and the N-terminal acylated and/or C-terminal amidated or esterified forms thereof wherein each of 1-4 cysteines is independently replaced by a hydrophobic amino acid or a small amino gacid.
Patent EP-0833842-B1 (EP)
Inventor: VERHEIJDEN GIJSBERTUS FRANCISC
IPC: A61K38/10
Filed: 1996-06-17
Granted: 1999-09-29
Abstract: The invention relates to the use of novel peptides in a peptide-induced tolerance therapy for the induction of tolerance to autoaggressive T cells associated with T-cell mediated articular cartilage destruction in autoimmune diseases, more specifically arthritis. The invention furthermore embraces pharmaceutical compositions comprising said peptides and a diagnostic method for the detection of autoreactive T cells in a test sample, said T cells being associated with T-cell mediated articular cartilage destruction in autoimmune diseases and test kits to be used in said method.
Patent EP-0837687-B1 (EP)
Title: Hapten modified tumor cell extract and methods of treating cancer
Inventor: BERD DAVID
IPC: A61K35/74
Filed: 1996-06-06
Granted: 2008-02-20
Abstract: A novel composition comprising a hapten modified tumor cell extract prepared from cancer cells, or cancer cell membranes or peptides obtained therefrom is disclosed. Also disclosed are methods of treating cancer comprising administering therapeutically effective amounts of cyclophosphamide and hapten modified tumor cell extracts, with or without adjuvants and cytokines. Also disclosed is a method of screening for cytokine production by tumors in order to determine the efficacy of treatment, wherein cytokin-specific nucleic acids from a patient tissue sample are amplified in order to produce a detectable signal.
Patent EP-0839400-B1 (EP)
Inventor: BOGNER GEORG
IPC: H01S5/02
Filed: 1996-07-16
Granted: 2003-06-04
Abstract: Die Erfindung bezieht sich auf ein Infrarot-Emitter-Bauelement mit einem handelsüblichen Lumineszenzdioden-(LED)-Gehäuse, welches zwei Elektrodenanschlüsse (13, 14) aufweist, von denen der eine einen wannenförmigen Reflektor (12) aufweist, und welches Gehäuse (11) ein optisch transparentes, elektrisch nichtleitendes Verkapselungsmaterial (16) aufweist. Erfindungsgemäß ist vorgesehen, daß in dem wannenförmigen Reflektor (12) des Lumineszenzdioden-(LED)-Gehäuses (11) ein Halbleiterlaserchip (1) befestigt ist. Der Halbleiterlaserchip (1) weist eine Quantenwannenstruktur auf, insbesondere mit einer gestrainten Schichtenstruktur, beispielsweise MOVPE-Epitaxieschichten mit der Schichtenfolge GaAlAs-InGaAs-GaAlAs. In dem optisch transparenten, elektrisch nichtleitenden Material (16) des Lumineszenzdioden-(LED)-Gehäuses (11) kann ein darin eingebrachtes Diffusormaterial (17) vorgesehen sein, welches hinsichtlich Art und Konzentration derart ausgebildet bzw. eingebracht ist, daß sich in Verbindung mit dem im Lumineszenzdioden-(LED)-Gehäuse (11) verkapselten Halbleiterlaserchip (1) eine Abstrahlcharakteristik bzw. eine Vergrößerung der wirksamen Emissionsfläche ergibt, die vergleichbar ist mit der einer handelsüblichen Infrarotleuchtdiode.
Patent EP-0840738-B1 (EP)
Inventor: BOMBARDELLI EZIO
IPC: C07C323/41
Filed: 1996-06-21
Granted: 2002-01-16
Abstract: The present invention relates to novel colchicine derivatives having antiproliferative, antineoplastic, antiinflammatory and muscle relaxant activities; said derivatives include novel colchine nitrogen amides for use either as such or after derivatization of the hydroxyl at C3 of the aromatic ring and at C10 of the tropolone ring. These novel compounds have a cytotoxicity on human tumoral cell lines comparable with colchicine but, in comparison with the latter, they are much more active on cells resistant to the usual antiblastics. The compounds can be included in pharmaceutical formulations useful for the intravenous, oral and topical administrations.
Patent EP-0840973-B1 (EP)
Inventor: SENTINELLI MAURO
IPC: H04M17/02
Filed: 1996-07-24
Granted: 2001-04-04
Abstract: Radio mobile terminal provided with an additional chip card reader of prepaid chip cards, which can be made available both on a terminal realized according to the TACS technology and on a terminal employing the GSM technology. The prepaid chip card embodies the payment means for the radio mobile telephone service.
Patent EP-0850457-B1 (EP)
Inventor: TRIAL FRANCOIS
IPC: G06K7/08
Filed: 1996-08-12
Granted: 2004-12-29
Abstract: Device for reading cheques, particularly the track comprising the account identification number, and comprising two stacked generally parallelepiped-shaped parts (1, 2) made from an insulating material and joined to each other so as to leave an intermediate longitudinal slot having a width that only allows one cheque (8) to be inserted therein. The upper part (1) has a first read head (4) for reading the cheques (8), and a second read head (4') for detecting surrounding electromagnetic interference and for correcting the signal from the first read head (4) so that the indiciae to be read on the cheque are restored without error. The signals from both heads (4, 4') are processed by an electronic card (7) located in a housing (6) in the upper part (1), two magnets (5, 5') being located on either side of the first read head (4).
Patent EP-0900075-B1 (EP)
Inventor: TIROSH OREN
IPC: C08G65/335
Filed: 1996-12-10
Granted: 2002-04-03
Abstract: Ether-linked phospholipids, derivatized at the polar head group with polyethylene glycol chains having molecular weights greater than 2,000 daltons, are disclosed. Lipid bilayers containing these phospholipids show high oxidative stability. Also disclosed is the use of PEG-derivatized ether-linked lipids in moisturizing and radiation-protective cosmetic compositions.
Patent EP-0792893-B1 (EP)
Inventor: SCHIMPERNA GIULIANA
IPC: C08F8/30
Filed: 1997-02-07
Granted: 2002-07-17
Abstract: Polyolefins modified by radical grafting with an unsaturated polyfunctional compound containing an imide group and an ester group having general formula (I): <CHEM>
Patent EP-0814336-B1 (EP)
Inventor: CHAPOTEAU EDDY
IPC: G01N33/84
Filed: 1997-06-09
Granted: 2004-11-10
Abstract: The present invention provides a reagent for extracting lead ions from a variety of biological matrices such as human whole blood that has been anticoagulated with either heparin or EDTA, and lyophilized human blood and bovine EDTA whole blood. The released lead is measured in situ with a colorimetric porphyrin reagent without further manipulation of the supernatant. The lead ion releasing reagent can be used in conjunction with a variety of assay formats for the determination of lead in various biological fluids.
Patent EP-0824149-B1 (EP)
Inventor: NISHI KAZUNORI
IPC: A61K38/00
Filed: 1997-08-13
Granted: 2006-06-21
Abstract: This invention relates to glutamine:fructose-6-phosphate amidotransferase, or its partial peptide or a salt thereof; a DNA coding for the protein; a recombinant vector; a transformant; a method for producing the protein; a pharmaceutical composition comprising the protein, its partial peptide or a salt thereof; and an antibody against the protein or its partial peptide. The protein, its partial peptide or a salt thereof, and the DNA are useful for a prophylactic or therapeutic agent for hypoglycemia. The antibody can be used in the assay of the protein, its partial peptide or a salt thereof. The protein, its partial peptide or a salt thereof is useful as a reagent for the screening for candidate medical compounds.
Patent EP-0849493-B1 (EP)
Inventor: HEITZIG JUERGEN
IPC: F16F13/10
Filed: 1997-12-11
Granted: 2002-11-13
Abstract: The damper has an automatic hydraulic mounting with an acoustic coupling. It has two damping chambers (16,18), the upper one (18) of which is enclosed by a pliable membrane (34). Projections (36) on the outer side of the membrane, and/or axial or radial grooves give the membrane an elastic air cushion coupling at a rubber elastic spring unit (4) and a limit disc (24). A non-return valve (32) links the hollow zone (22) towards the air cushion (38), operated by the membrane, with a connection on the other side between the air cushion (38) and the outflow channel (40) into the outside. The outflow channel has a controlled closure as a switched magnet or valve.
Patent EP-0819671-B1 (EP)
Inventor: RIONDEL M ALAIN
IPC: C07C213/10
Filed: 1997-06-26
Granted: 2001-10-31
Abstract: Aqueous stabilised unsaturated quaternary ammonium salt(s) of the following formula( I), R1 = H or Me; R = Me or benzyl; X = Cl, Br, I or -CH3-SO4, obtained by the reaction, in the presence of water, of N,N-dimethylaminoethyl (meth)acrylate of formula (II), with a quaternising agent of formula R-X (III), with R and X as above. The solution contains a stabiliser associated with the monomer (II) and also a metal sequestering agent chosen from diethylenetriamine penta-acetic acid, its pentasodium salt, N-hydroxyethyl-ethylenediamine triacetic acid and is trisodium salt. Also claimed, is their method of preparation.
Patent EP-0959656-B1 (EP)
Inventor: HATLO JAN KARE
IPC: A01C23/02
Filed: 1997-02-14
Granted: 2003-07-02
Abstract: PCT No. PCT/NO97/00049 Sec. 371 Date Feb. 5, 1999 Sec. 102(e) Date Feb. 5, 1999 PCT Filed Feb. 14, 1997 PCT Pub. No. WO97/29626 PCT Pub. Date Aug. 21, 1997In a method for periodic depositing of liquid manure such as a slurry in a soil (80) the slurry is injected in a concentrated jet (9) under pressure with the result that forms and fills a groove (6) in the soil, which groove (6) is preferably closed after the injection. A device (1) for use in the method comprises at least one nozzle (5) with a breaker element (10) for periodic interruption of or opening for an injection jet (9) in an outlet direction (P2), the nozzle preferably being provided as an opening from a chamber (3, 29, 35, 38, 52, 72) pressurized with slurry. The breaker element (10) may be rotatably mounted about a rotation axis (22) which is parallel to the nozzle's outlet direction (P2), and is located beside the nozzle (5), with the result that during a rotational movement of the breaker element periodically interrupts the injection jet (9).
Patent EP-0892870-B1 (EP)
Inventor: RYYNAENEN SEPPO
IPC: B28B1/50
Filed: 1997-04-09
Granted: 2000-04-12
Abstract: The invention relates to a method for producing ceramic products in the form of earth building layers or prefabricated building elements. Finely powdered soil material which contains clay and finely powdered waste is expanded in a mobile heating chamber (1) at the temperature of 800 - 1300 DEG C which is maintained by burning fuel in the heating chamber (1) when rotating a drum like heating chamber. <IMAGE>
Patent EP-0898772-B1 (EP)
Inventor: HYLIN MATS
IPC: G03B21/00
Filed: 1997-04-23
Granted: 2001-11-07
Abstract: The display system has projectors (22) at a number of public places, e.g. railway stations. The projectors are connected and controlled by local computers (34,38) that are linked through a communication system, e.g. radio (14), to a central computer system (10). Projectors are many places of different types can be linked to this system. Also connected to the central system are information mediators (24). These may be advertisers or any other source requiring to present public displays. The information suppliers can be allowed to directly book dispaly time slots through the central computer which then organised the distribution of the display material.
Patent EP-0904315-B1 (EP)
Inventor: BREUNIG STEFAN
IPC: C08G77/38
Filed: 1997-06-12
Granted: 2003-05-07
Abstract: The subject-matter of the invention is a process for the preparation of silicone oils which are weakly colored and low in turbidity by hydrosilylation of polyorganohydrosiloxanes with different or identical synthons comprising at least one hydrocarbon-comprising ring in which is included an oxygen atom, the said reaction being carried out in the presence of a heterogeneous catalytic composition comprising a metal chosen from the group consisting of cobalt, rhodium, ruthenium, platinum and nickel deposited on an inert support.
Patent EP-0912510-B1 (EP)
Inventor: BAKER RALPH THOMAS
IPC: C07D207/267
Filed: 1997-06-30
Granted: 2003-05-07
Abstract: A process for producing unsaturated nitrogen containing compounds such as enamides, enamines and aryl amines/amides is disclosed. A vinyl halide or aryl halide is reacted with an -NH- containing compound in the presence of a catalytic amount of a catalyst precursor composition comprising zero-valent nickel and an organophosphine ligand. One step coupling of vinyl halides and aryl halides with -NH- containing compounds is made possible by practice of this invention.
Patent EP-0917700-B1 (EP)
Inventor: BARRY DAVID ROBERT
IPC: G09F3/00
Filed: 1997-08-05
Granted: 2001-11-07
Abstract: A self-adhesive label comprising a self-adhesive base carried on a backing of release material, a multilaminar portion disposed on a first portion of the base, a layer of adhesive on a second portion of the base adjacent to the first portion, and a printed cover sheet having a first edge portion which is adhered to the base by the layer of adhesive, a central portion which extends over the multilaminar label, and a second edge portion opposite to the first edge portion which is arranged to be held against the backing of release material thereby to retain the self-adhesive label in a closed configuration. <IMAGE>
Patent EP-0935607-B1 (EP)
Inventor: WUCHERPFENNIG KAI W
IPC: C07K14/74
Filed: 1997-08-15
Granted: 2004-07-28
Abstract: The present invention is directed to the field of immunology. In particular, the present invention is directed to the design, production, and use of recombinant fusion proteins derived, in part, from the proteins of the human Major Histocompatibility Complex.                                        00000
Patent EP-0873676-B1 (EP)
Inventor: SIEBERS JOSEF
IPC: A01C7/08
Filed: 1998-04-11
Granted: 2003-07-02
Abstract: The seed outlets are connected to the seed container by tubes (12,13), a distributor with vortex pipe (10) and supply pipes. The distributor (11) and vortex pipe are formed in one piece with the vortex pipe having sinusoidal vortex segments (24,25) which run across the flow direction and are arranged close together. The vortex pipe is shorter than 15 cm. The distributor has outlets (16,17) which adjoin the last vortex segment and point outwards at roughly 45 degs. The supply pipe has a 90 deg. curve (15) adjoining the vortex pipe and provided with a distribution nose (28) at the transition to the inside of the curve.
Patent EP-0872455-B1 (EP)
Inventor: DIFRANK FRANK J
IPC: C03B7/10
Filed: 1998-04-15
Granted: 2003-01-29
Abstract: A parallel shear apparatus (10, 110) for sequentially shearing each of a plurality of streams of molten glass from a glass feeder into gobs for processing into glass containers by a glass forming machine. The apparatus has first and second opposed carriages (12, 14) which are reciprocable along parallel slides (18, 20) toward and away from one another, each of the carriages (12, 14) carrying one or more opposed knife elements (32, 34), corresponding to the number of streams of molten glass, and the opposed knife elements overlap at the innermost limits of their travel to perform the shearing action. Motion of the carriages (12, 14) is actuated by a unidirectionally acting servo motor (36), which imparts oscillating motion to a bell crank (22, 122) through a connecting rod (46, 146). The oscillating motion of the bell crank (122) imparts simultaneous, opposedc, rectilinear motion to the carriages through connecting rods (26, 30), which are pivotally attached to the servo motor at diametrically spaced apart locations. The servo motor is mounted on a pivoting bracket (40, 140) that is urged to its normal operating position by a pneumatic cylinder (144) and is spring biased (150) away from its normal operating position in the event of a stoppage. The pneumatic cylinder (144) is cushioned to minimize shock loads caused bys a sudden retraction of the servo motor mounting bracket (140) and is adjustably mounted relative to fixed structure of the shear apparatus. <IMAGE>
Patent EP-0891794-B1 (EP)
Inventor: BOREL RENE
IPC: A43B7/16
Filed: 1998-07-06
Granted: 2003-10-01
Abstract: The skate comprises a boot (2) and a frame (5) with a series of wheels (6) with their axles in a straight line and a plate (4) to be fixed to the boot sole. The boot has an internal wedge (21) positioned under the wearer's heel to give a difference between the angle of the heel and the front section of the foot on the level of the metatarses. The wedge is made from a shock absorbing and elastically deformable material such as polyethylene or closed-cell foam, and it is fitted detachably inside the boot so that it can be changed for others of a different height. The material used for the wedge is different to that used for the outer sole of the boot, and the two can be produced together by over-moulding or bi-injection.
Patent EP-0928913-B1 (EP)
Inventor: BOARDMAN THOMAS A
IPC: F16J15/12
Filed: 1998-12-23
Granted: 2003-10-22
Abstract: A static gasket for sealing mating flanges which are clamped together by at least one fastener. A carrier holds the seal in a groove and the seal is protected from over compression by a compression limiter which is inserted into an aperture in the carrier. The compression limiter is crescent shaped to permit the insertion of a fastener stud into a through hole formed between the compression limiter and the aperture in the carrier. <IMAGE>
Patent EP-0911910-B1 (EP)
Inventor: BONVALLAT PIERRE
IPC: H01R13/52
Filed: 1998-10-06
Granted: 2002-08-21
Abstract: A gel or grease sealant is injected from the rear of the cavity, rather than the previously used direct front sealing, ensuring that good sealing without air bubbles is produced.
Patent EP-0953519-B1 (EP)
Inventor: BRAGADINA GIOVANNI
IPC: B65F1/00
Filed: 1998-04-28
Granted: 2000-11-08
Abstract: A container for collecting rubbish in a differentiated manner comprises a first and a second holding chamber (5a,5b) separated by a dividing baffle (6) presenting a fixed upper portion (9) and a lower portion (10) able to oscillate around a horizontal axis to modify the volume ratio between the first and the second containment chamber (5a,5b). A cradle element (14) associated to a base wall (2) of the container (1) or extensible connecting organs associated to the movable wall (10) guarantee that the lower edge (10b) of the movable wall (10) is constantly maintained essentially in contact on the base wall (2) to prevent mixing of the waste contained respectively in one and in the other chamber (5a,5b). <IMAGE>
Patent EP-0963418-B1 (EP)
Inventor: JAMES PHILLIP RICHARD
IPC: A61L2/26
Filed: 1998-02-13
Granted: 2002-09-18
Abstract: A steam-sensitive ink comprises, as active ingredient, a tetrazolium salt. The ink may be coated on, or impregnated into, a substrate to form a steam sterilization indicator.
Patent EP-0910866-B1 (EP)
Inventor: WIJENBERG CHRISTOFFEL
IPC: H01J17/16
Filed: 1998-03-16
Granted: 2004-06-23
Abstract: Cette invention se rapporte à une lampe à décharge haute pression possédant une puissance nominale d'au maximum 100 W. Cette lampe est dotée d'une enceinte de décharge possédant une paroi céramique translucide ayant une épaisseur 'd'. Dans l'enceinte à décharge délimitée par la paroi sont disposées deux électrodes dotées chacune d'une pointe, les deux pointes d'électrode étant espacées l'une de l'autre d'une distance EA. L'enceinte de décharge contient un produit de remplissage ionisable comportant au minimum du sodium et un halogénure. Conformément à cette invention, l'épaisseur 'd' de la paroi est supérieure ou égale à 1 mm.
Patent EP-0964677-B1 (EP)
Inventor: REDER ROBERT F
IPC: A61F13/00
Filed: 1998-02-24
Granted: 2006-08-16
Abstract: A sustained release formulation of buprenorphine is new. The composition comprises a transdermal delivery device which provides a first order release of buprenorphine over a 3-day dosing interval so that a maximum plasma concentration of 20 10 1052 pg/ml is obtained. the device then provides zero order kinetics over at least 2 more days.