baber/WOPTO huggingface dataset:
Patent CA-2493679-A1 (CA)
Title: Methods for generating enhanced antibody-producing cell lines with improved growth characteristics
Inventor: KLINE J BRADFORD
IPC: C12Q1/02
Filed: 2003-07-21
Abstract: The use of mismatch repair (MMR) defective antibody producer cells offers a method to generate subclone variants with elevated protein production such as antibodies. Using MMR defective cells and animals, new cell lines and animal varieties with novel and useful properties such as enhanced protein production can be generated more efficiently than by relying on the natural rate of mutation. These methods are useful for generating genetic diversity within host cells to alter endogenous genes that can yield increased titer levels of protein production. By employing this method, two genes were discovered whose suppressed expression is associated with enhanced antibody production.  Suppressed expression of these genes by a variety of methods leads to increased antibody production for manufacturing as well as strategies for modulating antibody production in immunological disorders. Moreover, the suppression of these two genes in host cells can be useful for generating universal high titer protein production lines.
Patent CA-2493705-A1 (CA)
Inventor: FIMREITE DUANE
IPC: A23L1/30
Filed: 2003-07-21
Abstract: L'invention concerne une poudre contenant une quantité élevée d'acide linoléique conjugué (ALC) ou d'une autre huile. Cette poudre comprend des triglycérides contenant de l'ALC ou une autre huile souhaitée, des acides gras libres d'ALC ou d'une autre huile souhaitée, ou des esters alkyliques d'ALC ou d'une autre huile souhaitée. La poudre selon l'invention s'écoule librement et présente de bonnes propriétés organoleptiques. Ladite poudre peut être utilisée en tant que supplément diététique ou être combinée à des denrées alimentaires pour former un produit alimentaire consommable par les animaux ou les êtres humains.
Patent CA-2493923-A1 (CA)
Title: Nucleic acids and corresponding proteins entitled 191p4d12(b) useful in treatment and detection of cancer
Inventor: GE WANGMAO
IPC: A61K39/00
Filed: 2003-04-23
Abstract: A novel gene 191P4D12(b) and its encoded protein, and variants thereof, are described wherein 191P4D12(b) exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I.  Consequently, 191P4D12(b) provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 191P4D12(b) gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T  cells reactive with 191P4D12(b) can be used in active or passive immunization.
Patent CA-2494478-A1 (CA)
Title: Fluorescence correlation spectroscopy instrument
Inventor: BULSECO DYLAN A
IPC: G01N21/78
Filed: 2003-08-01
Abstract: Disclosed is a portable fluorescence correlation spectroscopy instrument tha t includes an excitation source (10), at least one of alight focusing element (12) positioned to receive light emitted by the excitation source, a detecto r (40a, 40b) for detecting light, the detector positioned to receive light emitted by a sample excited by the excitation source, and a correlator coupl ed to the detector, the correlator for processing data received at the detector and providing data including autocorrelation data, crosscorrelation data, or a combination thereof.
Patent CA-2494844-A1 (CA)
Inventor: KIRN DAVID
IPC: C12N5/08
Filed: 2003-08-11
Abstract: The present invention concerns methods and compositions for the treatment of cancer and cancer cells using altered poxviruses, including a vaccinia virus that has been altered to generate a more effective therapeutic agent. Such poxviruses are engineered to be attenuated or weakened in their ability to affect normal cells. In some embodiments, methods and compositions involve poxviruses that possess mutations that result in poxviruses with diminished or eliminated capability to implement an antiviral response in a host. Poxviruses with these mutations in combination with other mutations can be employed for more effective treatment of cancer.
Patent CA-2495049-A1 (CA)
Inventor: JAIN NIKHIL
IPC: H04L29/06
Filed: 2003-08-14
Abstract: In a wireless communication system, a method and apparatus of communicating between at least one base station and a core network is claimed. Signaling messages and voice streams are transported using packet-switched protocols (IP). A CIC field (Circuit Identity Code) is used to identify at least one VoIP streams. The CIC field may be interpreted as a UDP port number for the voice over IP stream. Also, a synchronization source or contributing source filed of a RTP header may be used as the CIC field (fig. 1).
Patent CA-2495144-A1 (CA)
Title: Methods and reagents for treating infections of clostridium difficile and diseases associated therewith
Inventor: EISENSTEIN BARRY
IPC: A61K47/10
Filed: 2003-08-29
Abstract: The invention features methods and compositions including rifalazil for treating Clostridium difficile.
Patent CA-2495857-A1 (CA)
Inventor: ZHANG ZHENGMING
IPC: H01M50/586
Filed: 2005-02-03
Abstract: The invention is a method for preventing short circuiting in a lithium ion battery. The battery has an anode made of intercalation compound, a cathode made of an intercalation compound, and a separator having a thickness of 25 microns or less sandwiched between the anode and the cathode. The method includes the steps of rounding or beveling the edge portion of the cathode, so that during charging when the anode and cathode expand and squeeze the separator, the rounded or beveled edge portion of the cathode cannot cut the separator.
Patent CA-2497785-A1 (CA)
Title: Computer physical security device
Inventor: CARL STEWART R
IPC: F16M13/00
Filed: 1996-02-07
Abstract: A locking apparatus for securing a portable electronic device having an internal surface and defining a security slot. The locking apparatus has a first engagement member including a first aperture, and a first flange at a first distal end of the first engagement member. A second engagement member is provided which includes a second aperture, and a second flange at a second distal end of the second engagement member. A locking mechanism adapted to pass through the first aperture of the first engagement member and the second aperture of the second engagement member maintains engagement of the first flange and the second flange with the internal surface of the portable electronic device to secure the device. The present invention provides a simple, yet efficient, solution to the problem of inhibiting theft of portable equipment.
Patent CA-2500101-A1 (CA)
Inventor: NAKANO KEIJI
IPC: C07F1/08
Filed: 2005-03-10
Abstract: A one-dimensional coordination polymer having a linear structure and represented by general formula (I) given below:   (see formula I) where M denotes copper or nickel, X denotes a halogen atom, R denotes a pyrazine derivative represented by general formula (II) given below, and n is an integer:   (see formula II) where each of Z1 and Z2, which may be the same or different, denotes an atomic group required for forming a carbon ring by joining with a methylene chain the carbon atoms in the 2-position and 3-position or the carbon atoms in the 5-position and 6-position of the pyrazine ring, and * denotes the binding position with M included in general formula (I).
Patent CA-2502075-A1 (CA)
Title: Method for the automatic configuration of an ip telephony device and/or data, system and device implementing same
Inventor: JOUSSET RICHARD
IPC: H04L12/24
Filed: 2003-09-16
Abstract: The invention relates to a method for the automatic configuration of an IP telephony device and/or data (21')from a data transmission network with packet switching, which enables the device to obtain a lease on a virtual sub-network (1d) while it is physically connected to another virtual sub-network (1c). In this way, for example, another device (11') can share the same physical access port (41) to the network via a switch (50), without the two devices necessarily receiving a lease on the same sub-network.
Patent CA-2506096-A1 (CA)
Title: Protection a usage unique de la lunette ou de la partie superieure d'un siege d'aisances
Inventor: FERNANDEZ MATEU ALBERT
IPC: A47K13/16
Filed: 2003-11-14
Abstract: L'invention concerne une protection à usage unique de la lunette ou de la partie supérieure d'un siège d'aisances. De par sa configuration, l'objet de l'invention élargit sa protection aux parties latérales et à la partie frontale du siège d'aisances. Cette protection (2) est constituée d'une pièce qui recouvre la lunette (3) du siège d'aisances ou son extrémité supérieure lorsqu'aucun couvercle ne protège l'utilisateur par rapport au siège d'aisances (11).
Patent CA-2510753-A1 (CA)
Inventor: WOOLFORD SCOTT
IPC: G06Q30/02
Filed: 2003-12-18
Abstract: L'invention porte sur un procédé de réalisation de moyens de fidélisation des clients afin que ceux-ci achètent des marchandises ou des services par l'intermédiaire d'un réseau de vendeurs, ce procédé consistant à offrir à un client une récompense chaque fois que celui-ci satisfait aux conditions de récompense établies par un vendeur participant au système, la récompense pouvant être honorée par un vendeur participant du réseau lorsque le client remplit les conditions de conversion, la conversion de la récompense aboutissant au fait que le vendeur rembourseur fournit au client une autre récompense.
Patent CA-2512658-A1 (CA)
Inventor: HAVERINEN HENRY
IPC: H04L12/56
Filed: 2002-05-30
Abstract: The present invention provides an access point device arranged to receive data packets from one or more client devices and transmit them along an area network characterized wherein the access point device comprises security means arranged to configure the client data packets such that they are directed only to one or more permitted area network device(s).
Patent CA-2512960-A1 (CA)
Title: Surgical instrument incorporating electroactive polymer actuator blocking lockout mechanism
Inventor: TIMPERMAN EUGENE L
IPC: A61B17/00
Filed: 2005-07-22
Abstract: A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. The handle produces multiple firing strokes to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. One or more electrically activated lockout mechanisms, such as electroactive polymer (EAP) actuators, are biased to prevent firing unless activated. One lockout is a spring-biased side pawl firing mechanism enabled by an EAP block actuator. Another is a firing trigger EAP lock. Yet another is a closure yoke EAP lock.  Yet a further one is a manual retraction EAP lock that locks the firing mechanism. Thereby, various sensed or commanded inputs may be incorporated to prevent inadvertent firing.
Patent CA-2513184-A1 (CA)
Inventor: NAPPER ANDREW
IPC: C12Q1/00
Filed: 2004-01-16
Abstract: Methods and compositions for evaluating nicotinamide-releasing activities are provided herein. Figure (1) is a schematic depiction of the chemical structures of 14C-NAD, 14C-NAD bound to a boronate-based affinity resin, and 14C-nicotinamide is quantitated after flowing through the affinity resin.
Patent CA-2525393-A1 (CA)
Title: Methods of delivering anti-restenotic agents from a stent
Inventor: LITVACK FRANK
IPC: A61F2/06
Filed: 2004-05-21
Abstract: A method for decreasing the level of restenosis following a stent (10) placement medical intervention involves the continuous administration of a dose of an anti-restenotic agent, such as paclitaxel, from the stent to vascular tissue in need of treatment in a controlled, extended and substantially linear drug release profile. The method of substantially linear extended release increases the therapeutic effectiveness of administration of a given dosage. In one example, a method of reducing restenosis includes delivering paclitaxel from a stent (10) to an artery at a minimum release rate of 1 percent of the total dosage of paclitaxel on the stent (10) per day throughout an entire administration period from the time of implantation of the stent (10) until the time that substantially all the paclitaxel is released from the stent (10).
Patent CA-2527012-A1 (CA)
Inventor: HORN BEN
IPC: E21B43/12
Filed: 2005-11-14
Abstract: Embodiments of the present invention provide methods and apparatus for reducing kinetic energy of a plunger within a plunger lift system. In one aspect, a lubricator is provided at a surface of a wellbore, the lubricator having a sealed, pressurized chamber therein to cushion the plunger upon impact. In another aspect, a method is provided for reducing the kinetic energy of the plunger by providing a compressed gas chamber within a lubricator, moving a kinetic energy-reducing surface which is partially bounding the chamber, and compressing the gas within the chamber to reduce kinetic energy of the plunger and cushion the impact force of the plunger.
Patent CA-2528152-A1 (CA)
Title: Compositions and methods for treatment of disease with acetylated disaccharides
Inventor: ESKO JEFFREY D
IPC: C07H15/04
Filed: 2004-06-01
Abstract: Compositions and methods for treatment of disease with acetylated disaccharides and analogs thereof are provided.
Patent CA-2532650-A1 (CA)
Title: Method and system for delivery of assistance data
Inventor: RUDOLF MARIAN
IPC: H04B7/212
Filed: 2004-07-16
Abstract: A method and system is disclosed for providing assistance data to wireless transmit/receive units (WTRUs). The assistance data includes information regarding the access point's neighboring access points. The assistance data is transmitted to WTRUs using multicast and/or broadcast type signaling and facilitates ring and handover of WTRUs from one access point to another.
Patent CA-2534767-A1 (CA)
Title: Three-way call detection using steganography
Inventor: MARTIN THOMAS J
IPC: H04M3/56
Filed: 2004-08-04
Abstract: Three-way call detection is an important component of correctional facility telephone equipment because it helps restrict calling access by certain persons to certain restricted telephone numbers. Various three-way call detection methods exist, but all of these implementations suffer from one major limitation - the detection accuracy is not as high as is desired by the industry. The present invention improves detection accuracy, using "steganography." Steganography involves hiding one set of data or signals within another signal or carrier in such a way that its presence is virtually imperceptible to the end recipient, and potential even the originator of the carrier signal. Television producers use steganographic methods to encode data in video signals for security, distribution monitoring, piracy-control, and other reasons. The present invention involves a device that connects to a telephone, either at the line or handset interfaces, and produces a known signal that is steganographically hidden within the user's normal voice signal. Detection equipment, residing at another location, monitors signals on telephone calls and tests for the presence of the hidden signal or data generated by the invention. Once detection is achieved, appropriate action, such as terminating or recording the call, may be taken. Improved accuracy is achieved by choosing the appropriate hidden signal(s) - ones that never occur in the course of normal conversation and never get generated by telephone company equipment. Once detected, the presence of the signal guarantees the call was made to the restricted party from a particular phone line.
Patent CA-2538139-A1 (CA)
Title: Method for designing an integrated security system for a facility
Inventor: NOVIKOV JURY VITALIEVICH
IPC: G08B13/00
Filed: 2003-08-27
Abstract: The inventive method for designing an integrated security system for an obje ct consists in selecting type and number of sensors for the system taking into consideration a user's requirements and possible security threats, arranging said sensors in the space of a protected room in such a way that it is cover ed by sensor served areas respecting duplication requirements and in carrying o ut expert evaluation of the designed system. The expert evaluation method consists in forming computer data bases in the form of mathematical models o f the sensors describing the served areas and particularities of industrial security sensors, storing model of the room protected by designed system in said computer memory, in forming the model of the integrated security system by disposing the sensor models obtained from the data bases on the room mode l, testing the operation of the formed model of the integrated security system which is used for analysing of the designed integrated security system and i n modifying it taking into consideration the results of analysis.
Patent CA-2543389-A1 (CA)
Inventor: POOLE DWIGHT R
IPC: F16B7/10
Filed: 2006-04-13
Abstract: An improved extension pole (20) is provided having relatively shiftable outer and inner bodies (24, 26) with a manually operable locking mechanism (28). The mechanism (28) includes a stationary component (44) secured to outer body (24), with a bidirectionally rotatable component (46) supported on the component (44). The rotatable component (46) has a projecting locking segment (60) disposed about the inner body (24), with the segment (60) being offset. When the mechanism (28) is in its unlocked condition, the centerline of the segment (60) is substantially coincident with the centerlines of the inner and outer bodies (24, 26), thereby permitting free reciprocation of body (26); upon rotation of the component (46), the locking segment (60) comes into direct, frictional, locking engagement with the inner body (26) along a contact arc (68).
Patent CA-2545212-A1 (CA)
Title: Mould cavity structure
Inventor: HOENISCH MAREK
IPC: B29C45/34
Filed: 2004-11-05
Abstract: The invention relates to a mold cavity for the production of hollow molded parts. Said mold cavity forms a molding chamber (5) and comprises a cavity (1) whose inner contour matches the outer contour of the molded part that is to be produced in at least some sections thereof, a core (2) whose outer contour matches the inner contour of the molded part that is to be produced in at least some sections thereof, and a supporting ring (3) which at least partially surrounds the core (2) at least when the mold cavity is closed. Said supporting ring (3) is provided with an inner cone (9) while the core (2) is provided with a corresponding outer cone (8). Said cones (8, 9) are configured such that the inner cone (9) of the supporting ring (3) enters in contact with the outer cone (8) of the core (2) at least when the mold cavity is closed. In order to provide a mold cavity or a core and a supporting ring which can easily be adjusted to different molded parts while being easy to produce, neither the inner cone (9) of the supporting ring nor the outer cone (8) of the core (2) is located directly adjacent to the molding chamber (5).
Patent CA-2547038-A1 (CA)
Title: Apparatus useful for positioning a device on an endoscope
Inventor: SPIVEY JAMES T
IPC: A61J15/00
Filed: 2006-05-15
Abstract: A medical apparatus and method useful for positioning a device, such as an endcap, on an end of an endoscope, is disclosed. The apparatus can exert a pulling force on the endoscope through the endcap while a pushing force is applied to the endcap.  The apparatus can be used to press an endcap onto the distal end of an endoscope without grasping by hand a sheath in those applications where the endoscope is disposed in a sheath.
Patent CA-2547720-A1 (CA)
Inventor: BAREGGI ALBERTO
IPC: H01B3/20
Filed: 2003-12-03
Abstract: The present invention concerns a cable for use in a predetermined voltage class, said cable for use in a predetermined voltage class, said cable comprising: - at least one conductor; a at least one extruded insulating lay er surrounding said conductor, said insulating layer being made from a non- crosslinked insulating material comprising at least one thermoplastic polyme r and at least one dielectric liquid, said insulating layer having a thickness such as to provide a voltage gradient on the outer surface of the cable insulating layer not smaller than 1.0 kV/mm; and - a protective element arou nd said extruded insulating layer having a thickness and mechanical properties selected to provide a predetermined impact resistance capability, said protective element comprising at least one expanded polymeric layer, said thickness being sufficient to prevent a detectable insulating layer damage upon impact of at least 25 J energy. The insulating layer thickness and the protective element thickness can be selected in combination to minimize the overall cable weight while preventing a detectable insulating layer damage upon impact of at least 25 J energy.
Patent CA-2551047-A1 (CA)
Title: Valve pin guiding tip for a nozzle
Inventor: BABIN DENIS
IPC: B29C45/28
Filed: 2004-11-04
Abstract: An injection molding apparatus includes a manifold and a nozzle, which is received in an opening in a mold plate, including a nozzle channel for receiving the melt stream from the manifold channel, the nozzle channel being aligned with a first axis. A nozzle tip is received in a downstream end of the nozzle. The nozzle tip includes a melt channel for receiving the melt stream from the nozzle channel of the nozzle. A valve pin guiding portion is provided at a downstream end of the nozzle tip including an outwardly extending flange having a peripheral edge that abuts an inner wall of the opening to align the melt channel with a second axis through a mold gate. A valve pin is movable through the melt channel to selectively open the mold gate. Wherein the nozzle tip is flexible in order to compensate for the first axis and the second axis being out of alignment.
Patent CA-2551415-A1 (CA)
Title: Thiazole derivatives and use thereof
Inventor: QUATTROPANI ANNA
IPC: A61K31/427
Filed: 2005-01-11
Abstract: The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
Patent CA-2552038-A1 (CA)
Inventor: TYGARD EDWARD
IPC: B66F9/14
Filed: 2006-07-14
Abstract: A manipulator for use with a lift truck includes a guide assembly mountable on a mast of a lift truck, a carriage assembly supported for movement along the guide assembly, and an arm assembly mounted on the carriage assembly for supporting a lift truck attachment such as a clamping apparatus. The arm assembly may include two arms pivotable with respect to each other about a substantially vertical axis. The manipulator can move a load in a widthwise direction of a lift truck and between opposite widthwise sides of a lift truck.
Patent CA-2552836-A1 (CA)
Inventor: LUBBE PIETER W
IPC: B65D43/26
Filed: 2006-07-19
Abstract: A cup lid comprising a base cup lid having a drink-through opening formed therein in a planar top portion thereof, and a rotatable stopper associated therewith so as to selectively provide a sealed and unsealed relationship between said drink-through opening and a opening in said rotatable stopper. The base cup lid and the rotatable stopper are mated to one another by the use of convoluted portions on each part which form a sliding tongue and groove relationship. The rotatable stopper has an actuator that can be used to move the rotatable stopper from a closed position wherein the opening in the rotatable stopper and the drink-through opening in the base cup lid, are not aligned, to an open position where the opening in the rotatable stopper and the drink-through opening in the base cup lid, are aligned. An easily operated resealable cup lid is provided.