baber/WOPTO huggingface dataset:
Patent WO-2019075358-A1 (WO)
Title: Bace1 inhibitors for the treatment of alzheimer's disease
Inventor: GHOSH ARUN K
IPC: C07D487/04
Filed: 2018-10-12
Abstract: Described herein are compounds of the formulae (I)-(III) as well as pharmaceutical compositions comprising such compounds and methods for using such compounds/pharmaceutical compositions for treating Alzheimer's disease.
Patent WO-2019079739-A1 (WO)
Title: Optimized bedside safety protocol system
Inventor: HANDLER JONATHAN ALAN
IPC: G16H40/60
Filed: 2018-10-19
Abstract: Therapy device systems, modules, and methods, include memory, one or more processors, in communication with the memory, a plurality of medical therapy devices, a plurality of patient monitoring devices, and a protocol execution module, configured to execute on the one or more processors. The protocol execution module displays a plurality of protocols. The protocol execution module receives a selected protocol, associated with an individual medical therapy device being one of a plurality of medical therapy devices and associated with an individual patient monitoring device being one of a plurality of patient monitoring devices. The protocol execution module executes the selected protocol with the individual medical therapy device.
Patent WO-2019094186-A1 (WO)
Title: Système de versements dynamiques de voyage dans une place de marché électronique
Inventor: BAYER LEX
IPC: G06Q50/10
Filed: 2018-10-23
Abstract: L'invention concerne des systèmes et des procédés destinés à analyser une politique d'annulation pour un élément de voyage afin de déterminer des paramètres de paiement spécifiés pour l'élément de voyage, et pour chaque paiement d'une pluralité de paiements par versements en nombre prédéterminé, calculer une période de paiement pour chaque paramètre de paiement spécifié pour l'élément de voyage d'après un laps de temps avant que le paiement ne soit échu afin de satisfaire chaque paramètre de paiement et le nombre prédéterminé de versements. Les systèmes et procédés permettent en outre de sélectionner un nombre de paiements par versements prédéterminés de la pluralité de paiements par versements en nombre prédéterminé qui comporte une période optimale de paiement entre un paiement du versement final et la date de début de l'élément de voyage, de générer un échéancier de versements d'après le nombre sélectionné de paiements par versements prédéterminés, l'échéancier de versements comportant une date et un montant pour chaque paiement de versement, et de faire en sorte que l'échéancier de versements soit présenté via le dispositif informatique.
Patent WO-2019094471-A1 (WO)
Title: Système de croissance verticale
Inventor: FYVOLENT DOUGLAS
IPC: A01G31/06
Filed: 2018-11-07
Abstract: L'invention concerne un système de culture qui comprend une tour de culture creuse comportant des unités de plantation conçues pour contenir des plantes disposées sur l'extérieur de la tour, les unités de plantation ayant un passage qui s'étend jusque dans l'intérieur de la tour. La tour comprend également un orifice de vidange à une extrémité et une buse de distribution d'eau à l'autre extrémité. La buse comprend des ouvertures de sortie en communication fluidique avec l'intérieur de la tour, une ou plusieurs ouvertures de sortie de buse pouvant être carrées. Une enceinte entoure la tour, et une ou plusieurs sources de lumière sont montées sur l'enceinte afin de diriger la lumière vers la tour. La tour et l'enceinte peuvent être reliées à un cadre de suspension qui suspend l'ensemble du système hors du sol. Le système peut comprendre un système d'irrigation en boucle fermée et un système de nettoyage à réservoirs multiples. Des variables de système, telles que le débit d'eau, la température, l'éclairage et le niveau de nutriments de l'eau peuvent être réglées par ordinateur.
Patent WO-2019094534-A1 (WO)
Inventor: BETTIOL JEAN-LUC
IPC: C11D11/00
Filed: 2018-11-08
Abstract: A detergent composition, preferably a manual dishwashing detergent composition, comprising a surfactant system and at least one fatty acid processing fusion enzyme, wherein the at least one fatty acid processing fusion enzyme comprises at least two catalytic domains: i.e. a hydroperoxy fatty acid producing domain and a hydroperoxy fatty acid converting domain, and methods of using such compositions.
Patent WO-2019094580-A1 (WO)
Title: Système à ultrasons doté de détail haute fréquence
Inventor: LIU KAI WEN
IPC: A61B8/00
Filed: 2018-11-08
Abstract: L'invention concerne un système d'imagerie ultrasonore, configuré pour servir d'interface avec un transducteur ultrasonore à double fréquence ayant un ou plusieurs réseaux d'ultrasons basse fréquence et un ou plusieurs réseaux d'ultrasons haute fréquence. Le système d'imagerie produit des impulsions de commande à la fois pour le réseau d'ultrasons haute fréquence et le réseau d'imagerie ultrasonore basse fréquence. Des signaux d'écho analogiques sont traités pour produire une image ultrasonore basse fréquence et une image ultrasonore haute fréquence qui sont affichées simultanément. Le tissu représenté dans l'image ultrasonore haute fréquence est une partie du tissu présenté dans l'image ultrasonore basse fréquence.
Patent WO-2019099360-A1 (WO)
Inventor: REED DAVID
IPC: H04L29/08
Filed: 2018-11-13
Abstract: Initializing a computing system using dormant pages includes marking a set of guest physical addresses as dormant. It further includes, for each node in a plurality of physical nodes, designating a set of real physical addresses for zeroing. An operating system is executing collectively across the physical nodes.
Patent WO-2019104109-A1 (WO)
Inventor: MARKSON CHRISTOPHER
IPC: G06K9/62
Filed: 2018-11-21
Abstract: Un procédé selon l'invention comprend la capture d'une première image d'un médicament contenu par un réceptacle. Le procédé consiste à créer une seconde image sur la base de la première image. Le procédé consiste à déterminer un premier sous-ensemble de pixels de la seconde image les plus susceptibles de correspondre au réceptacle. Le procédé consiste, pour chaque point, à traiter la seconde image le long d'un premier axe en : définissant une ligne croisant perpendiculairement le premier axe au niveau du point et en comptant le nombre de pixels situés le long de la ligne qui sont dans le premier sous-ensemble. Le procédé consiste à déterminer des premier et second maxima locaux des nombres. Le procédé consiste à estimer des positions des premier et second bords du réceptacle sur la base des positions des maxima locaux. Le procédé consiste à définir une ellipse sur la base des premier et second bords et à exclure d'un traitement ultérieur les zones de la première image à l'extérieur de l'ellipse définie.
Patent WO-2020036617-A1 (WO)
Title: Polymeric cell culturing surface having high cell adhesion
Inventor: TAHA AHMAD
IPC: C12M3/04
Filed: 2018-12-07
Abstract: A polymeric substrate has a plasma treated contact surface which is roughened, hydrophilic and has a higher oxygen atomic content than the interior portion. The treated contact surface has an enhanced cell adhesion, cell growth and cell recovery rate. During the treatment, the contact surface is contacted with a process gas introduced through a gas inlet near the treated surface and radio frequency electrical power is introduced in the process gas, forming a treated contact surface that has improved cell recovery compared to an untreated contact surface. The process gas optionally can be nitrogen gas, oxygen gas, or a gas that contains nitrogen atoms, oxygen atoms, or a combination of nitrogen and oxygen atoms. The process optionally improves cell recovery of a chicken embryo cell culture from the treated contact surface.
Patent WO-2019113592-A1 (WO)
Title: Système et procédés d'étalonnage d'appareil de poursuite laser
Inventor: MEURET MARK
IPC: G01S17/88
Filed: 2018-12-10
Abstract: L'invention concerne un système et un procédé d'étalonnage d'un appareil de poursuite laser. Le système comprend un système de support permettant un déplacement rapide et facile d'un artefact dans une position et une orientation désirées et pour le maintien de l'artefact dans la position et l'orientation. Un miroir d'alignement réglable est couplé à une première extrémité de l'artefact de sorte que le système d'alignement plus précis de l'appareil de poursuite laser puisse être isolé pour déterminer une longueur de référence de l'artefact. Des mesures supplémentaires sont alors effectuées pour exercer une ou plusieurs sources d'erreurs dans l'appareil de poursuite. Le système de support comprend un positionneur et une poutre de support pour le positionnement et le support de l'artefact. L'artefact est couplé à la poutre de support au moyen de pinces cinématiques qui sont conçues pour réduire ou éliminer les erreurs associées à une surcontrainte de l'artefact. L'artefact est mobile entre une configuration déployée destinée à être utilisée et une configuration escamotable pour faciliter le stockage et le transport.
Patent WO-2019190602-A1 (WO)
Inventor: BEJCEK ANDREW
IPC: A01D101/00
Filed: 2018-12-13
Abstract: A transmission speed control system for a walk-behind lawn mower includes a transmission, a transmission positioning assembly, and an electronic control unit. The transmission is tiltable about and operably engaged with a drive axle shaft. The transmission positioning assembly tilts the transmission between first and second angular positions. A belt tension between a drive belt and a transmission pulley of the transmission continuously increases from a minimum belt tension when the transmission is in the first angular position to a maximum belt tension when the transmission is in the second angular position. The rotational drive force exerted on the drive axle shaft by the transmission and a resulting driving speed of the lawn mower vary proportionally with the belt tension. The electronic control unit controls the transmission positioning assembly to tilt the transmission based on target and detected driving speeds.
Patent WO-2019118671-A1 (WO)
Title: Dispositifs et procédés de traitement de tissus
Inventor: BACHRACH NATHANIEL
IPC: A61M1/00
Filed: 2018-12-13
Abstract: L'invention concerne des dispositifs et des procédés de traitement et de récolte de tissu adipeux. Les dispositifs, systèmes et procédés de l'invention permettent de filtrer et de récolter de petites particules de tissu adipeux. Lesdits dispositifs, systèmes et procédés comprennent un dispositif présentant un volume de remplissage intérieur et un volume de collecte de déchets extérieur séparés par un filtre. Les fluides et les petits éléments moléculaires passent à travers le filtre pendant le traitement du tissu et peuvent être retirés, tandis que les tissus adipeux d'intérêt restent à l'intérieur du filtre pour être recueillis et réinjectés.
Patent WO-2019133531-A1 (WO)
Inventor: MAINOLFI NELLO
IPC: C07K16/28
Filed: 2018-12-21
Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
Patent WO-2020106307-A1 (WO)
Title: Aryl-aniline and heteroaryl-aniline compounds for treatment of birthmarks
Inventor: KINCAID JOHN
IPC: A61K31/136
Filed: 2019-11-20
Abstract: Provided herein are compounds and pharmaceutical compositions thereof for treating a birthmark in a subject in need thereof, wherein the compound is according to any one of formula (1), (II), (III), (IV), and (V). wherein X1, X2, X3, R1, R2, R2a, R13, R13a, R23, R23a, R23b, R33, R33a, R33b, R43, R43a, R51, R53, R53a, R53b, bond "a", and subscript n are described herein.
Patent WO-2019143566-A1 (WO)
Title: Fruit and vegetable-based fermentate compositions and methods of making and using the same
Inventor: HUNDT MATTHEW
IPC: C12N1/20
Filed: 2019-01-14
Abstract: A method for producing a fermentate including the steps of obtaining a fruit or vegetable extract, treating the extract with a hydrolytic enzyme, mixing the extract with a fermenting microorganism, water, and a growth media to produce a liquid composition; and incubating the liquid composition at a controlled temperature and a controlled pH to produce a fermentate. A method for killing or inhibiting the growth of a contaminating microorganism on or within a food product, and a food product including a fermentate having a cellular mass component from a fermenting microorganism, a fermented fruit or vegetable extract and a hydrolytic enzyme are disclosed. A fermentate produced by any one of the methods described is contemplated. The fermentate may be a concentrated liquid or a dry powder and has the ability to inhibit the growth of a contaminating microorganism by 100% when diluted to less than 5% (w/v).
Patent WO-2019160642-A1 (WO)
Inventor: RALPH ALEXANDER B
IPC: H04R7/12
Filed: 2019-01-17
Abstract: La présente invention concerne un haut parleur d'aigus (tweeter) à diaphragme comprenant une structure annulaire ayant une partie supérieure et une partie inférieure, et un diaphragme en forme de dôme ayant une périphérie fixée à la partie supérieure de la structure annulaire et une ouverture positionnée de manière concentrique au niveau d'un sommet du diaphragme en forme de dôme. Le haut parleur d'aigus à diaphragme comprend également un conduit acoustique ayant une première extrémité ouverte couplée à l'ouverture et une seconde extrémité ouverte s'étendant à l'opposé de l'ouverture. Le haut parleur d'aigus à diaphragme est configuré comme un résonateur de Helmholtz pour augmenter un niveau de sortie sur une plage de fréquences.
Patent WO-2019168636-A1 (WO)
Inventor: TROMBETTA STEVEN
IPC: A63F13/35
Filed: 2019-02-05
Abstract: Systems and methods for discovery and detection of events in interactive digital content are provided. A plurality of game titles may be hosted on a gaming network platform, and gameplay data in sessions involving the plurality of game titles may be tracked in real-time. Each session may be associated with a stream. One or more event criteria may be stored for each of a plurality of predefined events of interest. An event of interest may be identified when the tracked gameplay data for a session meets the stored criteria. A list of available streams identified as including the identified event may be sorted, and a subset of the available streams may be identified as being at a top of the list. A notification may be provided to a spectator device, the notification including a link to one of the streams in the subset. The criteria for the event of interest may also be updated based on subsequent game data and feedback ( e.g. , use of the link).
Patent WO-2019160812-A1 (WO)
Title: Polycrystalline diamond from vitreous carbon and transition metal free carbonate catalyst and method of producing
Inventor: STOYANOV EMIL T
IPC: B24D3/06
Filed: 2019-02-11
Abstract: A transition metal catalyst free polycrystalline diamond compact having enhanced thermal stability is disclosed herein. The diamond compact may be attached to a hard metal substrate. The polycrystalline diamond body includes a plurality of diamond grains bonded to adjacent diamond grains by diamond-to-diamond bonds. Sintering of the PCD and the formation of diamond-to-diamond bonding is achieved by transforming graphene treated diamond crystals that are blended with non-metal additives at high pressure and high temperature into a diamond compact that is free of transition metal catalysts. Non-metal additives include vitreous and other non-equilibrium forms of carbon as well as Sr-, K- and Ca-containing carbon sources.
Patent WO-2019168932-A1 (WO)
Inventor: LI ALBERT
IPC: C12Q1/68
Filed: 2019-02-27
Abstract: The present disclosure provides an in vitro reagent for evaluating xenobiotic metabolism in a cell culture based assay. The in vitro reagent is an admixture of a cell culture medium and isolated intestinal mucosa comprising villi wherein the intestinal mucosa was eluted from a lumen of the intestine. The isolated mucosa comprises metabolically competent cells. Addition of a xenobiotic test compound to the in vitro reagent allows metabolism of the test compound by the isolated intestinal mucosa comprising villi.
Patent WO-2019169053-A1 (WO)
Inventor: SCHULTZ CHRISTOPHER
IPC: G06F3/048
Filed: 2019-02-27
Abstract: A system allows a user to create new designs for apparel and preview these designs before manufacture. Software and lasers are used in finishing apparel to produce a desired wear pattern or other design. The system provides important insight to the apparel creation process, so that the user may effectively work with others or understand the impacts of changes with others.
Patent WO-2019173728-A1 (WO)
Title: Crispr-nanoparticles and methods of use in brain disorders
Inventor: LEE HYE
IPC: A61K9/127
Filed: 2019-03-08
Abstract: Described herein are compositions and methods for treating diseases and disorders of the brain using a non-viral nanoparticle delivery of CRISPR. Disclosed herein are compositions comprising CRISPR-Gold compositions comprising DNA oligonucleotides, RNA-directed nucleases and guide RNAs. The methods include modulating expression of a gene in a cell using said compositions, inducing site-specific DNA cleavage in a cell, and treating a subject having fragile X syndrome caused by increased metabotropic glutamate receptor 5 signalling using the compositions disclosed herein.
Patent WO-2019177979-A1 (WO)
Title: Systems and methods for optimizing engine operations in gensets
Inventor: PIPER ERIK L
IPC: B60W10/04
Filed: 2019-03-11
Abstract: A system comprises a generator and an engine coupled thereto. The engine is configured to provide mechanical power to the generator. A controller is coupled to the engine and the generator and is configured to compare an engine operating parameter value to a load demand value indicative of a load exerted by the generator on the engine. The controller determines that the engine operating parameter value fails to match the load demand value. The controller determines an engine operating parameter threshold value at which the engine operating parameter value failed to match the load demand value, and sets the engine operating parameter threshold value as a maximum allowable engine operating parameter value for the engine.
Patent WO-2019209422-A1 (WO)
Title: Gratings with variable depths formed using planarization for waveguide displays
Inventor: COLBURN MATTHEW E
IPC: G02B5/18
Filed: 2019-03-13
Abstract: A manufacturing system performs a deposition of an etch-compatible film over a substrate. The etch-compatible film includes a first surface and a second surface opposite to the first surface. The manufacturing system performs a partial removal of the etch-compatible film to create a surface profile on the first surface with a plurality of depths relative to the substrate. The manufacturing system performs a deposition of a second material over the profile created in the etch-compatible film. The manufacturing system performs a planarization of the second material to obtain a plurality of etch heights of the second material in accordance with the plurality of depths in the profile created in the etch-compatible film. The manufacturing system performs a lithographic patterning of a photoresist deposited over the planarized second material to obtain the plurality of etch heights and one or more duty cycles in the second material.
Patent WO-2019191325-A1 (WO)
Inventor: ARGO BRAIN
IPC: A23K20/00
Filed: 2019-03-27
Abstract: La présente invention concerne des probiotiques lyophilisés microencapsulés ainsi que des procédés de préparation et d'utilisation de ceux-ci. Plus spécifiquement, l'invention concerne des microcapsules à faible activité de l'eau destinées à être utilisées dans des produits cosmétiques, des produits de soins de santé et des aliments. L'invention concerne également des produits cosmétiques et des produits de soins de santé à faible activité de l'eau sans conservateur contenant les microcapsules probiotiques.
Patent WO-2019191767-A1 (WO)
Title: High hydrogen utilization and gas recycle
Inventor: SMITH GARY J
IPC: C12P1/00
Filed: 2019-04-01
Abstract: Provided herein are systems and methods for recycling and supplementing off-gas from a gas fed reaction process. The systems and methods are particularly useful for bioprocesses that convert hydrogen gas into one or more biosynthetic products. By maintaining separate hydrogen and oxygen feed gas streams, and forming a recycle gas that introduces a target component of the supply gas to the bioreactor within a target concentration range, the yields, productivities, and safety profiles of the bioprocess can be enhanced.
Patent WO-2019195458-A1 (WO)
Title: System and method to cue specific memory recalls while awake
Inventor: HOWARD MICHAEL
IPC: A61M21/00
Filed: 2019-04-03
Abstract: Described is a system for cueing a specific memory in a waking state. The system sends an initiation signal to a memory recall controller to select a stored stimulation pattern previously associated with a specific memory of an event. The system signals to a memory recall controller to initiate delivery of the selected stimulation pattern to a brain in a waking state for a duration of the event via a brain stimulation system. Following completion of the event, the system signals for the memory recall controller to stop the brain stimulation system from delivering the selected stimulation pattern.
Patent WO-2019199873-A1 (WO)
Title: Techniques for considering uncertainty in use of artificial intelligence models
Inventor: HALDER BIBHRAJIT
IPC: G05D1/02
Filed: 2019-04-09
Abstract: An infrastructure is provided for improving the safety of autonomous systems. An autonomous vehicle management system (AVMS) controls one or more autonomous functions or operations performed by a vehicle or machine such that the autonomous operations are performed in a safe manner. The AVMS uses various artificial intelligence (AI) based techniques (e.g., neural networks, reinforcement learning (RL) techniques, etc.) and models as part of its processing. For an inferring data point, for which a prediction is made by AVMS using an AI model, the AVMS checks how statistically similar (or dissimilar) the inferring data point is to the distribution of the training dataset. A score (confidence score) is generated indicative of how similar or dissimilar the inferring data point is to the training dataset. The AVMS uses this confidence score to decide how the prediction made by the AI model is to be used.
Patent WO-2019226254-A1 (WO)
Title: Audio/video device with viewer
Inventor: SIMINOFF MARK
IPC: G08B3/10
Filed: 2019-04-16
Abstract: An audio/video (A/V) device may include or accommodate a viewer through a barrier. For example, an A/V device may include a first component for installation on an exterior surface of a door, a second component for installation on an interior surface of the door, a viewer that extends through an opening in the door, and a flexible connector that electrically couples the first component and the second component. The A/V device may enable use of an existing hole in the door as part of a door viewer, while also providing the functionality of an A/V device. For example, the A/V device may be configured to receive an input using a button on the first component, generate image data using a camera on the first component, and send the image data to a network device.
Patent WO-2019209994-A1 (WO)
Title: Apparatus, system and method for detecting and monitoring inhalations
Inventor: POCREVA III JOHN
IPC: A61M15/00
Filed: 2019-04-24
Abstract: Described herein are an interactive apparatus and methods for sensing and measuring real-time characteristic patterns of a subject's use of a dry powder inhalation system. The inhaler device can be used in a wireless communication mode to communicate with a display to assess the subject's usage of the inhalation system concurrently as the inhalation is performed and thus the subject's inhalation can be evaluated as well as the performance of the inhalation system. The system can also detect the identity of the medicament, its dosage, lot, expiration, etc. and the characteristic profile of a dry powder formulation emitted from the inhalation system in use and allows effective delivery of powder doses. Data obtained can be transmitted to a digital application and can be analyzed for optimal therapeutic utility.