baber/WOPTO huggingface dataset:
Patent PT-1226269-E (PT)
Inventor: XU YUAN
IPC: C12N9/72
Filed: 2000-11-01
Abstract: A process is described for monitoring the effectiveness of a purification process in removing plasminogen activator (PA) endogenous to Chinese hamster ovary (CHO) cells from a sample containing human tPA or variants thereof. This process comprises incubating the sample with a protease capable of specifically cleaving the Arg275-Ile276 bond of human wild-type tPA and then with denaturing/reducing agents in respective amounts effective to reduce the disulfide bonds of human wild-type tPA; subjecting the sample to a reversed-phase high-performance liquid chromatography step, and analyzing the elution profile from the chromatography step for the amount of PA endogenous to the CHO cells present therein.
Patent PT-1164612-E (PT)
Inventor: BURMESTER HEINO
IPC: H01H35/14
Filed: 2001-06-06
Abstract: The device has a spherical inertial body (3) held in a rest position by a permanent magnet (2) with an opposing elastic conductive membrane (4) and circuit board (5). When stimulated the inertial body moves, impacts on the membrane and makes a contact between the conducting tracks. The cavity (1d) accommodating the inertial body causes a directionally selective triggering characteristic as a result of its shape.
Patent PT-1180609-E (PT)
Inventor: HSU TAI-PING
IPC: F16B25/00
Filed: 2001-06-19
Abstract: A screw (3, 5, 6) includes a shank portion (31, 51) and a head portion (311, 511) on one end of the shank portion (31, 51). The shank portion (31, 51) has a continuous spiral screw thread (32, 52, 62) with a plurality of turns formed thereon. The screw thread (32, 52, 62) has an upper thread surface (32a, 52a), a lower thread surface (32b, 52b), and a cutting line (32c, 52c) that interconnects the upper and lower thread surfaces at a radial edge of the upper and lower thread surfaces distal to the shank portion (31, 51). Each of at least some of the turns of the screw thread (32, 52, 62) is formed with from two to six adjacent concave facets (321, 521, 621) along the cutting line (32c, 52c). Each of the concave facets (321, 521, 621) has a radial width ranging from about 60 to 120 degrees. Each pair of the adjacent concave facets (321, 521, 621) forms a pointed corner (322, 522, 622) at the cutting line (32c, 52c). <IMAGE>
Patent PT-1171244-E (PT)
Title: Method and device for painting motor vehicle bodies
Inventor: HERWIG GERNOT
IPC: B05C13/02
Filed: 2001-01-30
Abstract: A process and apparatus for painting vehicle bodies in which the bodies are moved past at least one paint-applying application device with the aid of a conveyor system, said application device for its part being guided by an application machine, and in which faces of the vehicle body which have different inclinations are painted.
Patent PT-1294414-E (PT)
Inventor: HOEMANN CAROLINE D
IPC: A61L27/50
Filed: 2001-06-29
Abstract: The present invention relates to a new method for repairing human or animal tissues such as cartilage, meniscus, ligament, tendon, bone, skin, cornea, periodontal tissues, abscesses, resected tumors, and ulcers. The method comprises the step of introducing into the tissue a temperature-dependent polymer gel composition such that the composition adhere to the tissue and promote support for cell proliferation for repairing the tissue. Other than a polymer, the composition preferably comprises a blood component such as whole blood, processed blood, venous blood, arterial blood, blood from bone, blood from bone-marrow, bone marrow, umbilical cord blood, placenta blood, erythrocytes, leukocytes, monocytes, platelets, fibrinogen, thrombin and platelet rich plasma. The present invention also relates to a new composition to be used with the method of the present invention.
Patent PT-1393277-E (PT)
Inventor: GAMACHE DANIEL A
IPC: A61K31/165
Filed: 2002-05-17
Abstract: NF-kappaB inhibitors are useful for treating dry eye disorders and other disorders requiring the wetting of the eye.
Patent PT-1392446-E (PT)
Inventor: MACKEL WILFRIED
IPC: B04B9/12
Filed: 2002-05-23
Abstract: The invention relates to a centrifugal separator ( 100 ) comprising a centrifugal frame ( 40 ), a rotatable, vertically arranged, drive spindle ( 100 ) provided with a drum ( 12 ), and a motor ( 90 ) having a vertical rotor axis ( 91 ). The spindle ( 10 ) is rotatably mounted in a bearing pot ( 20 ) and is mounted in a manner that permits it to three-dimensionally move about a pivot (G) in relation to the centrifugal frame ( 40 ). The housing of the motor ( 90 ) is rigidly fixed to the centrifugal frame ( 40 ), with the rotor axis ( 91 ) of the motor ( 90 ) aligned with the longitudinal axis ( 11 ) of the drive spindle ( 10 ) when at rest. The motor rotor is connected to the spindle ( 10 ) at a coupling point (K) via a flexible coupling element ( 70 ). The spindle ( 10 ) is mounted in the bearing pot ( 20 ) at at least two interspaced bearing points ( 22, 24 ) by means of antifriction bearings. The bearing pot ( 20 ) is joined to the centrifugal frame ( 40 ) via elastic bearing elements ( 50 ).
Patent PT-1409467-E (PT)
Title: A n-acylsphingosine glucosyltransferase inhibitor
Inventor: HIRTH BRADFORD H
IPC: C07B61/00
Filed: 2002-07-16
Abstract: Disclosed is a novel enantiomeric synthesis of ceramide-like inhibitors of UDP-glucose:  N -acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis.
Patent PT-1567440-E (PT)
Title: Sheave assembly for an elevator system
Inventor: RICO FERNANDO
IPC: B66B11/00
Filed: 2002-11-25
Abstract: The elevator system has an elevator car (12) selectively movable along a guide rail and a machine positioned and supported atop of the rail. A sheave assembly (32) is supported on the car and accommodates the rail within a hoistway. The assembly has two sheave portions (54) rotatable about a common axis, with a spacing between the portions, where the rail extends into the spacing.
Patent PT-1546134-E (PT)
Title: Piperazine substituted aryl benzodiazepines
Inventor: SCHAUS JOHN MEHNERT
IPC: A61P25/18
Filed: 2003-07-28
Abstract: Described herein are compounds of formula (I) wherein: is an optionally benzo-fused five or six member aromatic ring having zero to three hetero atoms independently selected from N, S, and O; Alk is (C<SUB>1-4</SUB>) alkylene or hydroxy substituted (C<SUB>1-4</SUB>) alkylene; X is oxygen or sulfur; R<SUP>1 </SUP>is hydrogen, (C<SUB>1-6</SUB>) fluroalkyl, (C<SUB>3-6</SUB>) cycloalkyl, or (C<SUB>1-4</SUB>) alkyl, wherein the (C<SUB>1-4</SUB>) alkyl is unsubstituted or substituted with hydroxy, methoxy, ethoxy, OCH<SUB>2</SUB>CH<SUB>2</SUB>OH, or -CN; R<SUP>2 </SUP>is H, halogen, (C<SUB>1-6</SUB>) fluoroalkyl, (C<SUB>1-6</SUB>) cycloalkyl, OR<SUP>4</SUP>, SR<SUP>4</SUP>, NO<SUB>2</SUB>, CN, COR<SUP>4</SUP>, C(O)OR<SUP>4</SUP>, CONR<SUP>5</SUP>R<SUP>6</SUP>, NR<SUP>5</SUP>R<SUP>6</SUP>, SO<SUB>2</SUB>NR<SUP>5</SUP>R<SUP>6</SUP>, NR<SUP>5</SUP>COR<SUP>4</SUP>, NR<SUP>5</SUP>SO<SUB>2</SUB>R<SUP>4</SUP>, optionally substituted aromatic, or (C<SUB>1-6</SUB>) alkyl, wherein (C<SUB>1-6</SUB>) alkyl is unsubstituted or substituted with a hydroxy group; R<SUP>3 </SUP>is hydrogen (C<SUB>1-6</SUB>) fluoroalkyl, (C<SUB>2-6</SUB>) alkenyl, Ar, (C<SUB>1-4</SUB>)alkyl-Ar, or (C<SUB>1-4</SUB>) alkyl wherein (C<SUB>1-4</SUB>) alkyly is unsubstituted or substituted with a phenyl; R<SUP>4 </SUP>is hydrogen, (C<SUB>1-6</SUB>) alkyl, (C<SUB>1-6</SUB>) fluoroalkyl, or optionally substituted aromatic; R<SUP>5 </SUP>and R<SUP>6 </SUP>are independently hydrogen, (C<SUB>1-6</SUB>) alkyl, or optionally substituted aromatic, R<SUP>7 </SUP>is hydrogen, (C<SUB>1-6</SUB>) alkyl, (C<SUB>1-6</SUB>) fluoroalkyl, or optionally substituted aromatic; R<SUP>8 </SUP>and R<SUP>9 </SUP>are independently hydrogen, (C<SUB>1-6</SUB>) alkyl, or optionally substituted aromatic; Ar is optionally substituted phenyl, napthyl, monocyclic heteroaromatic or bicyclic heteroaromatic; Z<SUP>1 </SUP>and Z<SUP>2 </SUP>are independently selected from hydrogen, halogen, (C<SUB>1-6</SUB>) alkyl, (C<SUB>1-6</SUB>) fluoroalkyl, OR<SUP>7</SUP>, SR<SUP>7</SUP>, NO<SUP>2</SUP>, CN, COR<SUP>7</SUP>, CONR<SUP>8</SUP>R<SUP>9</SUP>, NR<SUP>8</SUP>R<SUP>9</SUP>, and optionally substituted aromatic; and all salts, solvates, optical and geometric isomers, and crystalline forms thereof. Also, described are the use of the compounds of formula (I) as antagonists of the dopamine D2 receptor and as agents for the treatment of psychosis and bipolar disorders, and pharmaceutical formulations of the compounds of formula (I)
Patent PT-1518918-E (PT)
Title: Fuels compositions and methods for using same
Inventor: COLUCCI WILLIAM J
IPC: C10L1/18
Filed: 2004-09-07
Abstract: A fuel composition and methods for using it for controlling deposit formation in a spark-ignition internal combustion engine, such as a direct injection engine, comprising a spark-ignition fuel, a detergent, and a deposit inhibitor compound. <??>The detergent is selected from a Mannich base detergent and a polyetheramine detergent. The deposit inhibitor compound comprises a succinimide compound or a Manganese compound.
Patent PT-1673365-E (PT)
Title: Process for the preparation of z-flupentixol
Inventor: MAIORANA STEFANO
IPC: C07D335/12
Filed: 2004-09-29
Abstract: The present invention relates to a process for the separation of flupentixol isomers, particularly, a process for the preparation of Z-flupentixol and the decanoate ester and novel synthetic intermediates thereof.
Patent PT-1775498-E (PT)
Title: Transmission for a motorized agricultural working vehicle
Inventor: PUBERT JEAN-PIERRE
IPC: A01B33/08
Filed: 2006-10-13
Abstract: The transmission has a planet gear (21) mounted pivoting around a delivery wheel to take two positions. A planet gear support (2) has two stop portions, where one of the portions contacts with a stop (103) of a case (1) and the gear is engaged with a pinion (122) of an intermediate wheel (12), in one of the positions. One stop portion (23) contacts a stop (102) of the case and the gear is engaged with a pinion (112) of the wheel (12), in the other position. The passage between the positions is controlled by a cable activated from a hand lever of an agricultural equipment e.g. lawnmower.
Patent PT-1803853-E (PT)
Title: Method for creation underground diaphragm walls carried out with control and adjustment of the vertical positions and diaphragm wall so manufactured
Inventor: MAURO GRAVA
IPC: E02D13/04
Filed: 2006-01-03
Abstract: The invention refers to a procedure for constructing diaphragm walls for reinforcing the land and diaphragm wall so manufactured.  The procedure involves constructing diaphragm panels adjacent to each other, continuously controlling and adjusting the verticality (both lengthways and crossways) and subsequently casting the concrete in the dig after positioning an appliance which is fitted with a device to control and adjust the verticality to guarantee perfect adherence between the faces of the joints in adjacent panels.  If required, when faced with extensive pressure or movement of the ground, the procedure provides the use of a flexible joint that guarantees a continuous barrier  The use of the described procedure is essential to guarantee the efficiency of the constructed product.
Patent PT-1726673-E (PT)
Title: Tool for coldforming operations with improved performance
Inventor: ENGSTROEM HAKAN
IPC: C22C29/08
Filed: 2006-05-19
Abstract: The present invention relates to a cemented carbide tool for the deep drawing operations, especially as the ironing dies, of the manufacturing of aluminium or steel beverage cans. The cemented carbide comprises WC with an ultra fine grain size and 5-10 weight-% Co, and including grain growth inhibitors (V and/or Cr) and with a specific relation between HV30 and cobalt content.
Patent PT-1960429-E (PT)
Title: Immunoglobulins directed against nogo
Inventor: HAMBLIN PAUL A
IPC: C07K16/22
Filed: 2006-12-14
Abstract: The present invention relates to antibodies to NOGO, pharmaceutical formulations containing them and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorder
Patent PT-2061436-E (PT)
Title: Ibuprofen-effervescent preparation having a high dissolution rate and method for the production thereof
Inventor: GRUBER PETER
IPC: A61K31/19
Filed: 2007-08-30
Abstract: Effervescent ibuprofen composition comprises active granules comprising a water-soluble ibuprofen salt and a base, and effervescent granules comprising an acid and a component that forms carbon dioxide. An independent claim is also included for producing a composition as above by a method in which the active granules are produced by intensively mixing ibuprofen free acid with a base without adding water. ACTIVITY : Analgesic; Antiinflammatory; Antipyretic. MECHANISM OF ACTION : None given.
Patent PT-2243405-E (PT)
Title: Capsule for preparing a drink and method for preparing a drink using such capsule
Inventor: ACCURSI GIOVANNI
IPC: A47J31/40
Filed: 2007-06-05
Abstract: A capsule for preparing drinks containing a substance to be extracted and comprising at least a first wall (2) designed to form an inlet wall for the water to be injected into the capsule, and a second wall (3) designed to form an outlet wall for a drink obtained by the interaction between the water and the substance to be extracted. The second wall (3) has at least one cut (10) extending in a linear fashion, substantially made without removing material from the second wall (3), and delimited by two adjacent portions (11) of the second wall drawn near one another. The cut (10) has a size and/or shape such that, after the adjacent portions (11) delimiting it have drawn near one another again if necessary, substantially, directly or indirectly, it prevents the passage of liquid and allows the passage of air, said adjacent portions being deformable towards the outside of the capsule in such a way to form an opening for the beverage flowing out. A method using such capsule for the preparation of a drink is also claimed.
Patent PT-744477-E (PT)
Inventor: HESCH ROLF
IPC: D01B1/14
Filed: 1996-05-14
Abstract: A process for removing wood or fibre from bast fibre washes is claimed. The raw material is subjected to a preliminary comminution before the removal to form pieces that are of a pourable or flowing consistency. The pieces are subsequently de-fiberised in a mill that rotates at a high speed.
Patent PT-749973-E (PT)
Inventor: DIETER ARLT PROF DR
IPC: C07F9/50
Filed: 1996-06-10
Abstract: Enantiomerically pure 5,5'-dichloro-6,6'-dimethoxybiphenyl-2,2'-diyl-bis-(disubstd. phosphine) cpds. of formula (I) are new. R = phenyl (opt. substd. by 1-3 of R<1>, OR<1>, NO2, NH2, NHR<1> and NR<1>2), 1-7C alkyl or 3-7C cycloalkyl; R<1> = 1-6C alkyl. N.B. Formula (I) as given in the specification is incorrect. Also new are complexes (A) of (I) with Gp. VIII metals, pref. rhodium, ruthenium or iridium.
Patent PT-876300-E (PT)
Inventor: BRYANT STEPHEN D
IPC: C02F1/00
Filed: 1996-09-27
Abstract: The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one thiourea to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one thiourea to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the bactaria. The thiourea used in the method of the invention has the following formula a compound of the formula: The present invention also relates to compositions containing thiourea compounds and useable in the above methods. The compositions comprise at least one thiourea in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
Patent PT-998292-E (PT)
Inventor: DAIFOTIS ANASTASIA G
IPC: A61P43/00
Filed: 1998-07-17
Abstract: Disclosed are methods for inhibiting bone resorption in mammals while minimizing the occurrence of or potential for adverse gastrointestinal effects. Also disclosed are pharmaceutical compositions and kits for carrying out the therapeutic methods disclosed herein. The compounds are bisphosphonates selected from the group consisting of alendronate, cimadronate, clodronate, tiludronate, etridronate, ibandronate, risedronate, piridronate, pamidronate, zolendronate, optionally in combination with a histamine H2 antagonist.
Patent PT-989846-E (PT)
Inventor: MAES DANIEL H
IPC: A61K9/00
Filed: 1998-09-22
Abstract: The present invention relates to a cosmetic or pharmaceutical emulsion for topical application to the skin comprising an irritating agent and at least one non-disruptive emulsifier. In a preferred embodiment the irritating agent is a retinoid. The invention also provides a method for decreasing the irritation on the skin caused by an irritating active agent in a topical cosmetic or pharmaceutical emulsion which comprises employing as an emulsifier at least one of an alkyl polyoside, a grafted water soluble protein on a hydrophobic backbone, and lecithin.
Patent PT-1035860-E (PT)
Inventor: BOHACH GREGORY I
IPC: C07K14/31
Filed: 1998-12-01
Abstract: Pyrogenic toxins, such as staphylococcal enterotoxins, modified in the disulfide loop region are provided. The modified toxins retain useful biological properties but have substantially reduced toxicity compared to the corresponding unmodified native toxin. The native pyrogenic toxins are typically modified by deletions within the disulfide loop region to produce modified enterotoxins having 100-fold or greater decrease in toxicity.
Patent PT-1040830-E (PT)
Inventor: LOURENCO LUDGERO SOUSA DA SILV
IPC: A61K31/423
Filed: 1998-12-21
Abstract: The present invention provides a medicament for neurodegenerative diseases comprising zonisamide or an alkali metal salt thereof as an active ingredient. The present medicament can be used in the prevention and treatment of neurodegenerative diseases such as Parkinson's disease, Huntington's disease, choreic syndrome and dystonic syndrome in mammals (including human).
Patent PT-985414-E (PT)
Inventor: HOWARD HARRY RALPH
IPC: A61K31/495
Filed: 1999-05-05
Abstract: A method for treating glaucoma and ischemic retinopathy in a mammal, comprising administering to said mammal a therapeutically effective amount of a compound of the formula <CHEM> or a pharmaceutically acceptable acid addition salt thereof, wherein n, X, Y and Ar are as defined in the specification.
Patent PT-1052246-E (PT)
Inventor: NAKAZATO ATSURO
IPC: C07C229/50
Filed: 1999-01-27
Abstract: Fluorine-containing amino acid derivatives represented general formula (I), pharmaceutically acceptable salts thereof or hydrates of the same, wherein X<1> represents hydrogen or fluorine; and R<1> and R<2> are the same or different and each represents hydrogen or lower C1-10 alkyl. These compounds are useful as drugs, in particular, group 2 metabotropic glutamate receptor agonists for treating and preventing psychiatric disorders such as schizophrenia, anxiety and associated diseases, depression, dipolar disturbance and epilepsy, and neurological diseases such as drug addiction, cognition disorder, Alzheimer's disease, Huntington's chorea, Parkinson's disease, motility disturbance associating muscular stiffness, cerebral ischemia, cerebral insufficiency, spinal cord lesion and head disturbance. <CHEM>
Patent PT-1113717-E (PT)
Inventor: WETTENDORF CHRISTOPH SCHULZE
IPC: A01K1/01
Filed: 1999-09-16
Abstract: The invention relates to a method for the disposal of excrements of animals kept in a stable, wherein solid manure is separated from liquid manure in the stable and separately removed from the stable and separately stored and/or subjected to further processing. The new system is characterized in that the removal of solid and liquid manure and storing/further processing thereof is effected before the onset of decomposition and in that further processing of the solid manure comprises at least the following steps: surface expansion of the fresh manure and drying of the manure with a humidity content preventing decomposition. The invention also relates to a device for implementing the method.
Patent PT-1127471-E (PT)
Inventor: ALLEN HYMEL JAMES
IPC: H04M3/533
Filed: 1999-09-30
Abstract: A wireless subscriber unit (30) contains an advertisement manager (56). The advertisement manager (56) is programmed to assign an advertisement icon (54) to a message indicator (46) on the display (42) of the wireless subscriber unit (30). Assignment of the advertisement icon (54) to the message indicator (46) associated with a message (26) may be based on a predetermined algorithm in the advertisement manager (56), or based on a notification received from the wireless communication system (10).
Patent PT-1021356-E (PT)
Inventor: HUBER HANS-PETER
IPC: B65D81/32
Filed: 1999-08-05
Abstract: The invention relates to a multi-chamber container comprising cups (1.1, 1.2) which are covered by a common covering film (1.4). The cups are separated from one another by a connecting element (1.5)on which the covering film is sealed in such a way that, when applying pressure on one of the cups, this cup is interconnected to one or more adjacent cups by removing the covering film from said connecting element. The sealing strength on the common edge, over which the covering film and cups are interconnected, is selected such that it is high enough to prevent the connection between the covering film and the cups from detaching in the edge area due to this pressure. This solution establishes many examples for application especially with respect to the type and composition of the media accommodated in one of the cups. This can concern the use of liquid media. Applicators of different types, especially of types which expand when moistened, can be accommodated in the cups so that the multi-chamber container can also, for example, be directly used for the transdermal application of liquid active substances.
Patent PT-1123542-E (PT)
Inventor: GUILLON JEAN-LOUIS
IPC: G09F3/03
Filed: 1999-10-19
Abstract: A sealing assembly designed to co-operate with a screw provided with a tightening slot by being mounted therein in such a manner that once said assembly is sealed the tightening slot is hidden in a manner that is not reversible except by destroying the seal, and further comprising a breakable drive suitable when the sealing assembly is subjected to a tightening action, for driving the screw in a tightening direction inside a receptacle provided for this purpose and for breaking once the screw becomes blocked, so as to prevent any loosening action being applied via the breakable drive.
Patent SG-22694-G (SG)
Title: Message service system network
Inventor: KEPLEY GARRY DUANE
IPC: H04M3/50
Filed: 1994-02-07
Abstract: This invention relates to business communication systems and, in particular, to a message service system network that interconnects a plurality of message service systems and provides a voice mail message transfer capability between voice mail message service systems. The voice mail message transfer is performed as a computer-to-computer data file transfer operation over high speed data lines. The data file consists of the digitally encoded and compressed voice mail message to which is appended the message sender's name and telephone number as well as the message recipient's telephone number.