baber/WOPTO huggingface dataset:
Patent NZ-237170-A (NZ)
Title: Substituted oxetanones and medicaments thereof.
Inventor: DERUNGS ROMANO
IPC: A61K31/337
Filed: 1991-02-20
Abstract: Novel oxetanones inhibiting pancreatic lipase, of the formula <IMAGE> in which Q, R<1> and R<2> have the meaning given in the description, are disclosed, which are prepared starting from the corresponding beta -hydroxycarboxylic acids.
Patent NZ-240476-A (NZ)
Title: 2,4-diaminoquinazoline derivatives; pharmaceutical compositions
Inventor: COE JOTHAM WADSWORTH
IPC: C07D491/056
Filed: 1991-11-05
Abstract: PCT No. PCT/US91/07254 Sec. 371 Date May 5, 1993 Sec. 102(e) Date May 5, 1993 PCT Filed Oct. 10, 1991.2,4-Diaminoquinazoline derivatives as potentiators of chemotherapeutic agents in the treatment of cancer.
Patent NZ-242396-A (NZ)
Title: 6-hydroxyalkoxy-pyrimidin-4-yl benzenesulphonamide derivatives; pharmaceutical compositions and preparatory processes
Inventor: BURRI KASPAR
IPC: A61P9/10
Filed: 1992-04-16
Abstract: Sulphonamides of the formula I, in which the symbols R<1>-R<6>, X, Y and n have the meaning given in the description and which are in some cases novel compounds, and salts thereof can be used as active compound in the production of drugs for the treatment of circulatory disorders, in particular hypertension, ischaemia, vasospasms and angina pectoris.
Patent NZ-270865-A (NZ)
Title: 7-phenyl-2,4,6-heptatrienoic acid derivatives; pharmaceutical and cosmetic compositions
Inventor: BERNARDON JEAN-MICHEL
IPC: A61Q5/00
Filed: 1995-04-04
Abstract: Polyenic cpds. of formula (I) and their salts and optical and geometric isomers, are new. R1 = -CH3, -CH2-O-R9, -CH2-O-CO-R10 or -CO-R11; R2, R3, R5 = H or lower alkyl; R4 = H; R6 = H, 1-20C alkyl, -O-CH2-O-CH2-CH2-O-CH3 or -O-R13; or R4+R6 together with the adjacent benzene ring form a naphthalene ring; R7, R8 = (i) H, (ii) 1-20C alkyl, (iii) cycloaliphatic gp., (iv) -O-CH2-O-CH2-CH2-O-CH3, (v) -O-R13 or (vi) -S(O)nR13; provided that R7 and R8 are not (i), (iv), (v) or (vi) at the same time; R9 = H or lower alkyl; R10 = lower alkyl; R11 = (a) H, (b) lower alkyl, (c) -N(R')R" or (d) -OR12; R', R" = H, lower alkyl, mono- or poly-hydroxyalkyl, aryl (opt. substd.) or an amino acid, peptide or sugar residue or together form a heterocyclic gp.; R12 = H, 1-20C alkyl, alkenyl, mono- or poly-hydroxyalkyl or opt. substd. aryl or aralkyl, or a sugar, aminoacid or peptide residue; R13 = H or 1-20C alkyl; n = 0, 1 or 2.
Patent NZ-273801-A (NZ)
Title: Crystalline anhydrous mycophenolate mofetil complexed as a salt with chloride, sulphate, phosphate, or acetate anion; intravenous formulations
Inventor: FU ROGER CHERNG
IPC: A61K9/00
Filed: 1994-09-12
Abstract: The crystalline anhydrous salt formed by complexing mycophenolate mofetil with an anion selected from the group chloride, sulfate, phosphate and acetate (in particular the hydrochloride salt), and pharmaceutical compositions, intravenous formulations and a kit thereof, and associated methods of treatment.
Patent NZ-301472-A (NZ)
Title: Control of pathogens with mixtures of saponin compounds and aromatic aldehydes
Inventor: EMERSON RALPH W
IPC: A01N25/00
Filed: 1995-12-29
Abstract: Methods and compositions employing saponin as synergist in combination with a natural product, such as an aromatic aldehyde, are provided for controlling the colonization and/or growth of plant and animal pathogens, such as fungi, insects, arachnids and non-aquatic mollusks, on materials such as plants, plant parts and agricultural products before, during, after and/or processing. The invention finds use in treating agricultural crops for pathogenic organisms which colonize the surfaces of plant parts and tissues and controlling the level of toxic metabolites present in consumable products derived from plant materials, as well as reducing the health risk associated with their consumption. A method of employing saponin to kill nematodes is also provided.
Patent NZ-332226-A (NZ)
Title: Process for the preparation of 6-(arylcarbonyl-4-oxiomo-dihydrobenzothiopyran herbicides and intermediates useful therein
Inventor: DOEHNER ROBERT FRANCIS
IPC: A01N43/18
Filed: 1998-10-07
Abstract: -(arylcarbonyl)-4-oximo-dihydrobenzothiopyran  herbicides of the formula 1 R1 and R2 are each independently C1-4alkyl W1 is -SCR4R5CR6R7COOH W2 is H or W1 and W2 may together with the carbons to which they are attached form a ring in which W1 and W2 represent  formula II R3, R4, R5, R6 and R7 are each independently H or C1-4alkyl Z is O or NOR8 and R8 is H, C1-4 alkyl or C1-4 haloalkyl or when Z is NOR8, the steroisomers thereof. Also claimed is the process for making this compound.
Patent NZ-332933-A (NZ)
Title: Food or drink utensil or container with frangible portion for re-attachment to selected other objects
Inventor: O'BRIEN JAMES PATRICK
IPC: B25G1/00
Filed: 1998-11-23
Abstract: Disclosed is a food or drink utensil or container having parts 105 and 110 separated by a frangible zone 110. The parts may be separated with subsequent recycling of the utensil prevented or discouraged in that these parts are not re-attachable to each other. However, a separated part is capable of re-attachable to further selected objects. Typically, selected parts 101,101',102,102' are re-attachable to each other to form a patterned structure 600, typically for competition and promotional purposes.
Patent NZ-335376-A (NZ)
Title: A cover for a food dispensary
Inventor: TRIPODI DOMINICO
IPC: A47F3/00
Filed: 1997-10-30
Abstract: A cover (12) for a food dispensary (10) that is configured such that in use human access to food arranged under the cover is substantially restricted to the use of an utensil (22).  Cover (12) includes, or is capable of interacting with, at least one opening (20) into the dispensary. The arrangement of cover (12) and the opening is such as to enable a receptacle (30) to be passed through the opening into the dispensary in use, so that food can be manipulated onto the receptacle using the utensil.
Patent NZ-500346-A (NZ)
Title: Improved methods for processing recombinant activated protein C by anionic chromatography, freeze-drying or filtration
Inventor: BAKER JEFFREY CLAYTON
IPC: C12N9/64
Filed: 1998-04-24
Abstract: Protein C is a serine protease and naturally occurring anticoagulant that plays a role in the regulation of homeostasis by inactivating Factors Va and VIIIa in the coagulation cascade. Human protein C is made in vivo primarily in the liver as a single polypeptide of 461 amino acids. A method of processing an aqueous solution of recombinantly produced human activated protein C (aPC), by conducting the processing at an ionic strength between 150 mM and 400 mM, at a temperature between 0 and 10 degrees Celsius and a pH of between 5.5 to 6.3 is described. The protein is essentially purified by chromatographic separation and concentrated by filtration.
Patent NZ-502139-A (NZ)
Title: Chimeric interleukin-6 soluble receptor/interleukin-6 fusion protein (sIL-6R/IL-6) to treat malignant melanoma cells
Inventor: REVEL MICHEL
IPC: A61P1/16
Filed: 1998-07-09
Abstract: Described are chimeric proteins constructed from the fusion of the naturally occurring form of the soluble IL-6 receptor and the naturally occurring form of IL-6.  These proteins are useful for treatment of cancer and liver disorders, enhancement of bone marrow transplantation, and treatment of other IL-6 related conditions.
Patent NZ-503155-A (NZ)
Title: Apparatus for making panels comprising cladding, a frame and insulation
Inventor: TEXTOR SCOTT ROSS
IPC: E04G21/16
Filed: 2000-03-01
Abstract: An apparatus for assembling panels of the type comprising a metal frame having cladding attached to each face thereof, comprises a plurality of linearly arranged spaced apart stations for combining panel components.  The stations are linked by a conveyor and include an initial station 1 comprising a first transporter for delivering a sheet of cladding from a supply thereof to a preset position on the conveyor at initial station 1.  An adhesive applicator GL1 is for applying adhesive in a desired pattern to the upper surface of the sheet of cladding and a second transporter is for delivering a frame from a supply (station 1B) thereof to the upper surface of the sheet cladding for affixing thereto with the frame aligned with the sheet of cladding.  A further station 4 is for receiving the partially assembled panel from initial station 2 via the conveyor to a preset position at the further station.  Further station 4 comprises an adhesive applicator GL4 for applying adhesive in a desired pattern to the upper face of the frame and a transporter is for delivering a sheet of cladding from a supply thereof to the upper face of the frame for affixing thereto with the upper sheet of cladding in alignment with the lower sheet of cladding.  A final station 6 is for receiving the completed panel from further station 4.
Patent NZ-503800-A (NZ)
Title: Bile acid salts of metals with physiological action and the use thereof in therapy
Inventor: BARTOLI ENZO
IPC: C07J9/00
Filed: 1997-10-09
Abstract: There is disclosed: Bile acid salts with metal selected from the group of iron (III), copper (I), copper (II), zinc, cobalt, molybdenum, platinum, gold, manganese, vanadium, selenium, tin, nickel; pharmaceutical compositions thereof and the use of these bile acid salts for the preparation of medicaments for supply of oligoelements to the enterohepatic circle or for iron therapy.
Patent NZ-506598-A (NZ)
Title: Methods for treating conditions mediated by integrin alpha-and beta subunits, aka the vitronectin receptor
Inventor: ROGERS THOMAS E
IPC: A61K31/70
Filed: 1999-02-22
Abstract: Described are compounds of formula (1) wherein X and Y are the same or different halo groups and pharmaceutically acceptable salts and isomers thereof useful as ávâ3 integrin antagonists.  They are useful in pharmaceutical compositions and in methods for treating conditions mediated by ávâ3 by inhibiting or antagonizing ávâ3 integrins. Another object is to provide pharmaceutical compositions comprising compounds described above.  Such compounds and compositions are useful in selectively inhibiting or antagonizing the integrin and therefore in another embodiment relates to a method of selectively inhibiting or antagonizing the ávâ3 integrin.  Further described is the treatment or inhibition of pathological conditions such as osteoporosis, humoral hypercalcemia of malignancy, Paget's disease, tumour metastasis, solid tumour growth (neoplasia), angiogenesis, including tumour angiogenesis, retinopathy including diabetic retinopathy and macular degeneration, arthritis, including rheumatoid arthritis, periodontal disease, psoriasis, smooth muscle cell migration and restenosis in a mammal in need of such treatment.  Additionally, such pharmaceutical agents are useful as antiviral agents, and antimicrobials.
Patent NZ-513091-A (NZ)
Title: An adhesive anchor and system for sealing boreholes
Inventor: IRWIN JAMES C
IPC: F16B13/14
Filed: 2001-07-23
Abstract: An adhesive anchor system for disposition within an adhesive material disposed within a bore hole of a substrate for anchoring a fastener within the substrate.  It comprises a ribbed anchor member (20) having a threaded opening extending between first and second opposite ends thereof.  Also a tube member (30) being substantially coaxially aligned with the threaded opening of ribbed anchor member (20), having a first end portion fixedly connected in an integral manner to the first end of ribbed anchor member (20) so as to facilitate insertion manipulation of the ribbed anchor member (20) into the adhesive material disposed within the bore hole of the substrate.  Also provided is a second end portion into which a fastener can be inserted for threaded engagement with the anchor member (20) so as to be anchored within the substrate.  A cap member (40) covers the second end of the opening of ribbed anchor member  (20) so as to prevent the adhesive material, disposed within the bore hole of the substrate, from entering the second end.
Patent NZ-520969-A (NZ)
Title: Device for cushioning of compression surfaces of a mamography unit.
Inventor: LEBOVIC GAIL
IPC: A61B6/00
Filed: 2001-03-06
Abstract: According to the present invention, improved methods and apparatus are provided for providing cushioning and other ergonomic surfaces on devices requiring the patient or tissue to be compressed, such as radiography machines, fluoroscopy units, mammography units and the like. In particular a radiolucent pad element is provided for releasable attachment to at least one surface of a compression device to be used under x-ray, for example, during mammography. The pad element of the present invention can be disposable or constructed to be reusable and in some cases may be applied directly to the patient's breast. Furthermore, a cushioned compression paddle or x- ray plate is provided wherein said compression paddle or x- ray plate and said cushion can be separately or integrally formed.
Patent NZ-522216-A (NZ)
Title: Novel deoxynucleoside kinase enzyme variants which decrease the lethal dose of nucleoside analogues
Inventor: KNECHT WOLFGANG
IPC: A61K45/00
Filed: 2001-05-07
Abstract: An isolated mutated polynucleotide encoding a multi-substrate deoxyribonulcease kinase enzyme is described wherein the mutated polynucletiode when compared to the non-mutated polynucleotide when transformed into a bacterial cell decreases at least 4 fold the lethal dose (LD100) of at least one nucleoside analogue selected from AZT (3'-azidion-3'-thymidine, ara-A (adenosine-arabinoside; Vivarabine), ara-C (cytidine-arabinoside), 2'3'-dideoxycytidine (ddC), 2',3'-dideoxyadenosine (ddA) and 2-chloro-2'-deoxyadenosine (2CdA). A vector construct comprising a polynucleotide that encodes the enzyme variant is described and the polynucleotide can be use dint e preparation of a medicament for inhibiting a pathogenic agent, such as a virus, a bacteria or parasite, tumor cell, autoreactive immune cell in warm-blooded animal.
Patent NZ-522505-A (NZ)
Title: Resorcinol-formaldehyde resins
Inventor: COLLINS PETER JAMES
IPC: C08G8/22
Filed: 2002-11-08
Abstract: A process for the production of a resorcinol-formaldehyde resin, comprising the steps of combining from about 0.6:1.0 to about 1.0:1.0 molar ratio of formaldehyde and an aqueous solution of resorcinol together in the presence of a sufficient amount of a pH adjustment chemical, wherein the amount of pH adjustment chemical is sufficient to adjust the pH such that the pH of the reaction mixture is less than about 5.0.
Patent NZ-522759-A (NZ)
Title: A stent having an integral valve at the tip of the lower end section
Inventor: RIX GERALD HENNER
IPC: A61F2/04
Filed: 2001-05-25
Abstract: An indwelling ureteral (ureteric) stent constructed of a hollow flexible tube with an upper end section (1), a substantially straight middle section (2) and a lower end section (3). The upper and lower sections are preferably coiled. The coiled upper section has a diameter between 1 and 2.5 cm that retains the upper section (1) of the stent in the kidney, and has perforations in the surface to allow drainage of urine from the kidney into the tube. The lower coiled section (3) of the stent is G-shaped. The tip of this lower section assumes the horizontal portion of the G shape and contains an integral valve (6). The integral valve (6) maintains an open flow of urine from the kidney to the bladder, but prevents the reflux of urine into the kidney during bladder contraction. The stent further comprises a small cuff or series of studs behind said valve against which a stent pusher may rest.
Patent NZ-533652-A (NZ)
Title: A paving system
Inventor: HEAVEN DARRYLL LAWRENCE
Filed: 2004-06-21
Abstract: A paving system having a portable receptacle or receptacles placed on a surface wherein the receptacle or receptacles are filled with payers to provide a surface which can be walked on, and wherein the payers are able to be removed from the receptacle or receptacles when desired; the receptacle or receptacles having ground engaging feet able to assist in stabilizing the receptacle or receptacles in the face of some areas of uneven underlying ground.
Patent NZ-534219-A (NZ)
Title: Method for enhancing cellulose and modifying lignin biosynthesis in plants
Inventor: CHIANG VINCENT L
Filed: 2000-05-18
Abstract: An isolated polynucleotide sequence is described to comprise a cellulose synthase promoter of SEQ ID NO:3, a sequence conservative variant thereof, or a functional fragment thereof which binds to a transcription factor in a plant cell. The polynucleotide is described to be a stress-inducible promoter, to comprise at least one MSRE (mechanical stress regulatory element), which can be a tree. A method of increasing expression of a cellulose synthase in a plant involves delivering into the plant a cDNA encoding a protein; and a method for reducing the expression of a cellulose synthase in a plant comprises delivering into the plant a DNA in an antisense orientation. Methods for increasing or reducing cellulose biosynthesis in a plant are also described.
Patent NZ-536087-A (NZ)
Title: Flexible packaging
Inventor: SCHROEDER ALFRED A
IPC: B31B50/64
Filed: 2003-04-16
Abstract: Methods and apparatus for forming and filling a flexible package are provided in which an evacuation device (26) and a fitment (20) are attached to a sheet of flexible material (16). The sheet of flexible material (16) is formed into a package that is filled and sealed.
Patent NZ-538026-A (NZ)
Title: A process for packaging food products in a high modulus, temperature-resistant multilayer film
Inventor: COOK HUBERT J
IPC: B32B7/02
Filed: 2003-08-20
Abstract: Disclosed is a packaging process comprising the steps of: (A) supplying an elongate multilayer film comprising: (i) a first layer comprising cyclic olefin copolymer having a glass transition temperature of at least 125 Deg C; (ii) a second layer comprising at least one member selected from the group consisting of cyclic olefin copolymer having a glass transition temperature of at least 125 Deg C, polyamide, polyester, and polystyrene; wherein the first and second layers are on opposite sides of a tensile axis of symmetry of the multilayer film, with the film exhibiting from 0 to 45 degrees of transverse edge curl, a yield point of at least 1200 psi at a temperature of 85 Deg C, and an elongation at break of from 0 to 300 percent at 85 Deg C; (B) placing a plurality of product units on the film at desired intervals; (C) forwarding the film having product units thereon, while: (D) forming a tubing from the film so that product is inside the tubing upon reconfiguring the film to a tubing around the product, with longitudinal edge portions of the film being adjacent one another once the film has been reconfigured; (E) forming a longitudinal seal along a segment of the adjacent edge portions of the film, to form a sealed tubing segment, with a single product unit being inside of the sealed tubing segment; (F) forming a first transverse seal across the sealed tubing segment at a first location which is downstream of the single product unit; (G) severing the film downstream of the first transverse seal, and (H) forming a second transverse seal across the sealed tubing segment at a second location which is upstream of the single product unit; and (I) severing the sealed tubing segment from the multilayer film upstream of the second transverse seal, whereby a discrete packaged product is formed with the single product unit surrounded by the multilayer film; and wherein the forwarding of the film having the product units thereon is carried out by pulling on the film tubing with a means for making the first transverse seal and thereafter with a means for making the second transverse seal, while both the means for making the first transverse seal and the means for making the second transverse seal are at a temperature high enough to seal an inside layer of the film to itself. This process is particularly suitable for packaging of cheese products such as an individual cheese block, a set of stacked slices of cheese or a set of shingled slices of cheese.
Patent NZ-540382-A (NZ)
Title: Methods of using and compositions comprising immunomudulatory compounds for the treatment and management of myeloproliferative diseases
Inventor: ZELDIS JEROME B
IPC: A61K31/454
Filed: 2003-04-13
Abstract: Disclosed is a use of an immunomodulatory compound selected from: 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1 ,3-dione; 3-(4-amino-1-oxo-1 ,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione; and a compound of formula (I), wherein one of X and Y is C=O, the other of X and Y is C=O or CH2,and R2 is hydrogen or lower alkyl; or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent, in the preparation of a composition for treating or preventing a myeloproliferative disease in a patient. Particular second active agents are capable of suppressing the overproduction of hematopoietic stem cells or ameliorating one or more of the symptoms of a myeloproliferative disease. Pharmaceutical compositions comprising the above immunomodulatory compound and the second active agents are also disclosed, wherein the immunomodulatory compound and the second active agent are present in the composition in complementary amounts or synergistically effective amounts for the treatment, prevention or management of a myeloproliferative disease.
Patent NZ-542230-A (NZ)
Title: System for spore detection
Inventor: REINISCH LOU
Filed: 2005-09-05
Abstract: A method of detecting the presence of bacterial spores in a sample is disclosed. The method comprises, non-destructively to the spores, carrying out the steps of assessing the sample for fluorescence, subjecting the sample to UV radiation, and then reassessing the sample for an increase in fluorescence relative to any fluorescence assessed in the first assessing step. The presence of fluorescence at the assessing step and an increase of fluorescence of the reassessing step is indicative of the presence of spores.
Patent NZ-547878-A (NZ)
Title: Lottery wherein a merchant selling entries to the lottery obtains at least one sale of goods funded from the prize pool
Inventor: CARTER MARK JOHN
Filed: 2006-06-13
Abstract: A lottery system comprises a draw comprising a plurality of entries, a centralised prize pool stored on a database and a prize set associated with the draw with prizes from the prize set being awarded to winning entries in the draw. The entries have an associated entry fee and are sold or distributed to players through at least one selected merchant on a merchant network. The prizes from the prize set include at least one custom lottery prize. The at least one custom lottery prize is funded from the prize pool such that, for participation in the lottery, the selected merchant and/or the related merchant is arranged to obtain at least one sale computed from the prize pool as a result of the at least one custom lottery prize.
Patent NZ-551323-A (NZ)
Title: Modulation of wrn-mediated telomere-initiated cell-signaling
Inventor: GILCHREST BARBARA A
IPC: G01N33/50
Filed: 2005-05-19
Abstract: Disclosed is a method of screening for a modulator of WRN comprising a) providing a cell that expresses WRN; b) contacting candidate modualtors with said cell under conditions in which the modulator is taken up by the cell; c) measuring a property of the cell associated with activation of the DNA damage response pathway selected from the group consisting of cellular proliferation, cellular viability, cellular morphology, senescence associated beta-galactosidase activity, phospohorylation of p53 or p95, phosphorylation of ATM, phosphorylation of H2AX, induction of S phase arrest or induction of apoptosis, Wherein a change in the property compared to a control indicates a modulator of WRN.