baber/WOPTO huggingface dataset:
Patent CA-2695510-A1 (CA)
Inventor: RAMSEIER THOMAS M
IPC: C12N15/10
Filed: 2008-08-04
Abstract: The present invention provides methods and compositions for producing heterologous protein with improved yield and/or quality. A library of randomized ribosomal binding site sequences is provided for the identification of a translation initiation region sequence optimal for expression of the heterologous protein. Also provided are novel ribosomal binding site sequences, and vectors and host cells having those sequences. The library of randomized sequences is useful for screening for improved expression of any protein of interest, including therapeutic proteins, hormones, a growth factors, extracellular receptors or ligands, proteases, kinases, blood proteins, chemokines, cytokines, antibodies and the like.
Patent CA-2702317-A1 (CA)
Inventor: HARBESON SCOTT L
IPC: C07D413/12
Filed: 2008-07-08
Abstract: This disclosure relates to novel HTV integrase inhibitors their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treatingy HTV infections. Formula I: or a pharmaceutically acceptable salt, solvate, or hydrate thereof, wherein: each of R1, R2a, R2b, and R3 is independently selected from CH3, CDH2, CD2H, and CD3; Y1 and Y2 are each independently selected from H or D; R4 is selected from: formula D:and D; and when each R is CH3, at least one Y is D.
Patent CA-2705711-A1 (CA)
Title: Method and system for using message services for control and interaction in content distribution
Inventor: HERLEIN GREGORY CHARLES
IPC: H04L29/08
Filed: 2008-11-18
Abstract: A method for using a message service for communication in a content distribution environment includes soliciting a response from a user where the user is instructed to respond using a message service and an advertised point of contact. In response to a received message, an action associated with the received message is initiated and the location for execution of the initiated action is identified using the point of contact information communicated by the user. In circumstances in which shoppers have text-message enabled cell phones, a shopper can be solicited, in a display presenting content, to text a message to an identified point of contact for additional related content. A  playout system can then play the requested additional content on a display in close proximity to the shopper, where the display is identified using the point of contact information communicated by the user in the message.
Patent CA-2706973-A1 (CA)
Title: Alginate biomaterials for the treatment of hepatic disorders
Inventor: ILAN YARON
IPC: A61K31/738
Filed: 2008-11-27
Abstract: The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention are based on the administration, preferably, systemic administration, of a therapeutically effective amount of at least one biocompatible alginate biomaterial, any modification thereof and any combination thereof. The invention further provides methods for sustaining serum albumin levels, and/or reducing serum AST and ALT, in subjects suffering from hepatic disorder. Still further, the invention provides methods for reducing apoptosis and inducing cell proliferation in a damaged liver tissue of a subject suffering of hepatic disorder, using the alginate biomaterial described by the invention.
Patent CA-2709869-A1 (CA)
Inventor: WILLIAMS NEAL
IPC: C08F242/00
Filed: 2008-12-16
Abstract: A method of making a polymerisable ethylenically unsaturated macromonomer comprising the steps of: i) providing a chosen unsaturated non-mineral oil or a mixture of unsaturated non-mineral oils having a first blend of triglycerides, ii) treating the mixture of oils with a transesterification catalyst to produce a second blend of triglycerides different to the first, iii) reacting the second blend of triglycerides with an enophile having an acid, ester or anhydride moiety to form an adduct, iv) reacting the adduct with an ethylencially unsaturated monomer having a moiety reactive with the acid, ester or anhydride moiety of the enophile to form an intermediate, v) reacting the intermediate of step (iv) with a chain extender having at least two moieties reactive with the acid, ester or anhydride moiety of the enophile to form the ethylenically unsaturated macromonomer.
Patent CA-2711063-A1 (CA)
Title: Mass memory device and storage system
Inventor: COURTEILLE JEAN-MARIE
IPC: G06F13/38
Filed: 2009-02-02
Abstract: The invention relates to a mass storage device that comprises a bus of the MII bus family, connected to a programmable component managing the reading from and writing to the memory. This architecture enables the implementation of the control module of the remote device, wherein the communication between the controller and the programmable component can be transferred onto an Ethernet link connected to the bus of the MII family.
Patent CA-2711794-A1 (CA)
Title: 1d05 pcsk9 antagonists
Inventor: CONDRA JON H
IPC: C12N9/64
Filed: 2009-02-06
Abstract: Antagonists of human propro-tein convertase subtilisin-kexin type 9('PC-SK9') are disclosed. The disclosed antago-nists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of condi-tions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists.  Methods of making PCSK9-specific antago-nists as well as methods of using the antago-nists for inhibiting or antagonizing PCSK9 function are also disclosed and form impor-tant additional aspects of the present disclo-sure.
Patent CA-2712512-A1 (CA)
Inventor: DEPERTHES DAVID
IPC: A61K8/64
Filed: 2009-01-21
Abstract: This invention relates to therapeutic compounds which are inhibitors of serine proteases, to pharmaceutical compositions thereof and to their use in the treatment of the human or animal body. More specifically, the present invention relates to a method for the treatment, diagnosis or prognosis of skin diseases comprising the administration to a subject in need thereof of a therapeutically effective amount of a Serine protease inhibitor.
Patent CA-2713343-A1 (CA)
Title: A materials handling vehicle having a steer system including a tactile feedback device
Inventor: WETTERER GEORGE ROBERT
IPC: B66F9/20
Filed: 2009-01-27
Abstract: A materials handling vehicle (10) is provided comprising a frame comprising an operator's compartment (30), wheels supported on the frame, at least one of the wheels being a steerable wheel (74), and a steer-by-wire system associated with the steerable wheel to effect angular movement of the steerable wheel. The vehicle further comprises a control apparatus. Steer-by-wire system comprises a control handle(90), a tactile feedback device(100) and a steer motor(120).  Control apparatus is configured to increase tactile feedback device signal in response to an operator entering operator's compartment in order to inhibit an operator from making a quick turn request via a control handle. Depending on whether an operator is located within or outside operator' s compartment the steerable wheel can be moved to the different corresponding angular ranges.
Patent CA-2716036-A1 (CA)
Inventor: CHEN CHAO
IPC: H01H13/7065
Filed: 2010-09-27
Abstract: A key assembly for use in an electronic device is provided. The key assembly includes a plurality of dome switches and a plurality of single-piece keycaps.  Each keycap identifies a row of keyboard characters. Each keycap has a plurality of character-representing portions separated by deforming portions. Each character--representing portion is associated with a separate one of the plurality of dome switches. The key assembly further comprises a plurality of actuators for activating the dome switches. Each actuator has a first side which is engaged by one of the character representing portions of the keycap. Each actuator has a second side which engages the dome switch associated with that character-representing portion. In a rest state in which the keycap is not depressed, at least some of the actuators preload at least some of the dome switches by exerting a force upon the dome switches.
Patent CA-2718050-A1 (CA)
Inventor: LAFFERTY TERRENCE P
IPC: A23L5/10
Filed: 2008-09-22
Abstract: A thermally insulated susceptor structure comprises a dimensionally stable corrugated base, a first susceptor, and a second susceptor. At least one of the first susceptor and second susceptor may circumscribe one or more microwave energy transparent areas that allow the transmission of microwave energy through the respective susceptor and/or create localized fields that enhance heating, browning and/or crisping of an adjacent food item.
Patent CA-2720732-A1 (CA)
Inventor: SKARIA SIMON
IPC: G06F17/21
Filed: 2009-04-02
Abstract: Examples are related to systems and methods for controlling access to document files on a document server. One example system includes document files stored on a document server, at least one of the document files referencing a file lock, and a document access processing module. The example document access processing module includes a file sharing processing module that determines a coauthoring status of a software application of a client computer requesting access to the document file, and a file lock processing module that stores one or more file locks and that controls the setting and resetting of file locks. The example document access processing module uses the coauthoring status of the software application and the file lock status of a document file to determine whether a software application is permitted to have write access to the document file.
Patent CA-2720762-A1 (CA)
Inventor: DESHMUKH SOUMITRA
IPC: B01J23/887
Filed: 2009-04-06
Abstract: Methods for controlling series or series-parallel reactions are described.  Novel microchannel apparatus having mesoporous structures adjacent to bulk flow paths are described. Methods of synthesizing formaldehyde from methanol are also described.
Patent CA-2721797-A1 (CA)
Inventor: ZABOW GARY
IPC: B81C1/00
Filed: 2009-04-20
Abstract: A magnetic resonance contrast agent has a medium, and a contrast structure dispersed in the medium. The contrast structure comprises a magnetic material arranged to create a local region of a local magnetic field such that nuclear magnetic moments of a material when arranged within said local region precess at a characteristic Larmor frequency about a total magnetic field in the local region while in use, the characteristic Larmor frequency being identifiable with the contrast structure, and the total magnetic field in the local region being a substantially spatially uniform magnetic field.
Patent CA-2723587-A1 (CA)
Title: Abrogating proinflammatory cytokine production during oncolytic reovirus therapy
Inventor: COFFEY MATTHEW C
IPC: A61K35/765
Filed: 2009-05-27
Abstract: Provided herein are methods for treating a proliferative disorder in a subject comprising administering to the subject one or more reoviruses and one or more agents that modulate expression or activity of pro-inflammatory cytokines. For example, the agents may inhibit expression or activity of pro-inflammatory cytokines.
Patent CA-2725379-A1 (CA)
Inventor: GERBER JAMES S
IPC: B23P11/00
Filed: 2009-11-19
Abstract: A float structure for a WEC is designed to have a tapered underside to reduce the impact due to wave slam and bending moments while providing little reduction in the surface area responding to the wave surface in order to maintain the beneficial power generating capability of a "flat" float. The underside of the float presents an inverted wedge section to decrease loads associated with wave slamming. The float may have a generally toroidal or elliptical configuration at and about the "still" water line with the generally submerged underside of the float having a cross section shaped to have one or more inverted triangular sections extending between the outer perimeter of the float and its center to reduce impact loading due to wave slamming while maintaining power producing capability.
Patent CA-2725792-A1 (CA)
Inventor: JOU YU-CHEUN
IPC: H04L1/00
Filed: 2009-06-09
Abstract: Techniques to increase capacity in a wireless communications system. In an aspect, systematic non-transmission, or "blanking," of minimal-rate frames transmitted in a communications system is provided. In an exemplary embodiment, eighth rate frames in a cdma2000 voice communications system are systematically substituted with null- rate frames carrying zero traffic bits. Provisions are nevertheless made for the transmission of certain designated as "critical" by, e.g., a vocoder. The receiver detects the presence of null rate or non-null rate transmissions and processes the received frames accordingly, including updating an outer loop power control only in response to non-null rate frames. Further techniques for changing the pilot transmission gating pattern to assist the receiver in detecting null rate frames are provided. In another aspect, early termination of a signal transmission over a wireless communications link is provided. In an exemplary embodiment, a base station (BS) transmits power control groups (PCG's) for a frame over a forward link (FL) to a mobile station (MS) until accurate reception of the frame is acknowledged by the MS over a reverse link (RL), possibly before all PCG's of the frame are received over the FL. Possible ACK signaling methods are defined for channels associated with a cdma2000 wireless communications system. In another exemplary embodiment, techniques for reverse link early termination are also provided.
Patent CA-2725828-A1 (CA)
Inventor: WHITEHEAD JAMES H
IPC: H02G3/12
Filed: 1999-11-24
Abstract: A poke-through device for installation in a hole extending through a floor structure of a building includes a body having upper and lower ends and sized for insertion within the hole. The upper end of the body defines an interface mounting region and the lower end is adapted to electrically communicate with a junction box. One or more electrical interfaces can be mounted in the interface mounting region, the interfaces being electrical outlets and/or data jacks. The device also includes a cover assembly having a floor plate and at least one access door, the door being movable between a closed position enclosing the interface within the device, and an open position providing access to the interface through the hole.
Patent CA-2725966-A1 (CA)
Inventor: RIEGER BRIAN
IPC: B60B35/00
Filed: 2010-12-20
Abstract: A novel spindle nut assembly is presented comprising the following three components: a washer, a locking snap ring, and a nut. Each of these three components function together, and in conjunction with the spindle of a vehicle axle, to affix a wheel hub assembly onto the spindle of an axle. The three components comprising the spindle nut assembly incorporate design features allowing the components to interlock and resist loss of preload compression on the hub assembly.
Patent CA-2727553-A1 (CA)
Title: Supercondensateur et son procede de fabrication
Inventor: LIU JIANYUN
IPC: B01D61/44
Filed: 2009-05-15
Abstract: L'invention porte sur un supercondensateur qui comprend une première électrode, une seconde électrode, un premier support ionique configuré pour entrer en contact avec la première électrode pour fournir une première voie conductrice des ions pour le transport d'ions vers et depuis la première électrode, et une première couche de retenue configurée pour retenir le premier support ionique entre la première électrode et la première couche de retenue. En outre, le supercondensateur comprend un électrolyte dispersé entre les première et seconde électrodes pour fournir les ions, un premier collecteur de courant configuré pour entrer en contact avec la première électrode et un second collecteur de courant configuré pour entrer en contact avec la seconde électrode. L'invention porte également sur un procédé de fabrication du supercondensateur.
Patent CA-2729731-A1 (CA)
Inventor: MARSCHKE DEAN DAVID
IPC: C12M1/12
Filed: 2009-06-16
Abstract: L'invention porte sur un appareil et un procédé pour la collecte d'une matière cible à partir d'un échantillon liquide comprenant des espèces cibles qui contiennent la matière cible. L'appareil comprend un conduit (12) d'écoulement de fluide en communication avec un milieu de filtration (18) ayant une dimension des pores conçue pour retenir les espèces cibles sur celui-ci et laisser passer, en tant que filtrat, un lysat contenant la matière cible souhaitée. Un conduit (30) d'agent de lyse communique avec le conduit d'écoulement de fluide et achemine l'agent de lyse vers le milieu de filtration (18) pour lyser les cellules cibles, ce qui libère de cette manière la matière cible intracellulaire souhaitée. L'agent de lyse peut être amené à recirculer dans le milieu de filtration (18) pendant un temps suffisant pour permettre à une quantité suffisante de lysat de circuler dans le système pour la collecte du lysat et un essai subséquent.
Patent CA-2730139-A1 (CA)
Inventor: BROOKER ALAN THOMAS
IPC: C11D3/22
Filed: 2009-07-14
Abstract: The present invention relates to a particle comprising: (a) solid film-forming polymeric material; (b) liquid fabric-softening component; and (c) cationically charged polymeric material.
Patent CA-2731574-A1 (CA)
Inventor: DEL CASTILLO NIETO JUAN CARLOS
IPC: A61K31/34
Filed: 2009-07-21
Abstract: The present invention relates to new 3-substituted 6-nitrooxy-hexahydrofuro [3,2- b]furane derivatives possessing a superior pharmacological activity in thrombosis and in coronary ischemia models.
Patent CA-2732701-A1 (CA)
Inventor: ALFONSO JORGE R
IPC: E04C5/16
Filed: 2011-02-25
Abstract: A support structure for retaining a reinforcing bar ("rebar") in stacked layers.  Such a structure includes a first support structure retaining a first rebar for a first mat.  The support structure further includes a second support structure retaining a second rebar for a second mat. The first support structure and the second support structure can have similar configurations. The second support structure includes a first layer engaging portion, a second layer engaging portion and a support portion for connecting said engaging portions. The second layer engaging portion may include a reinforcing receptacle which includes a channel open to receive a rebar. The channel is defined by sidewalls that extend radially outward from an inner end receptacle.  The sidewalls spread so that the rebar can pass retaining features on the walls of the channel and rest in a bar retaining portion as the rebar moves down the channel.
Patent CA-2733386-A1 (CA)
Inventor: FRANKE DIETMAR
IPC: A23P30/34
Filed: 2009-09-17
Abstract: La présente invention concerne un procédé de fabrication d'un article à fumer composé de tabac. Selon le procédé, le tabac est préparé à l'aide d'au moins un procédé d'extrusion, incluant un compactage avec augmentation de la pression et de la température ainsi qu'un traitement mécanique et un séchage rapide, par détente, du matériau au niveau d'une sortie de l'extrudeuse (1), un fluide de traitement (7) réchauffé étant amené, en tant que fluide caloporteur, vers le tabac se trouvant dans l'extrudeuse (1) pour apporter la chaleur de traitement. L'invention concerne en outre un dispositif de fabrication d'un article à fumer, composé de tabac, comportant une extrudeuse (1) qui effectue un compactage du tabac avec augmentation de la pression et de la température ainsi qu'un traitement mécanique et un séchage rapide, par détente, du matériau à la sortie de l'extrudeuse (1), un réchauffeur (11) étant adjoint à l'extrudeuse (1) et réchauffant un fluide de traitement (7), lequel est amené vers l'extrudeuse (1), en tant que fluide caloporteur, pour apporter la chaleur de traitement.
Patent CA-2733636-A1 (CA)
Inventor: ANDERSSON TOMMY
IPC: C07K14/435
Filed: 2009-08-13
Abstract: The present invention relates to a novel unbranched carbamate derivative, in particular N-butyloxycarbonyl derivative of certain Wnt5-.alpha. peptides and to their use in the treatment of melanoma or gastric cancer, as well as a method for treating melanoma as well as a pharmaceutical composition comprising the same derivative.
Patent CA-2733884-A1 (CA)
Title: High yielding soybean variety 91y61
Inventor: FABRIZIUS MARTIN A
IPC: A01H5/10
Filed: 2011-03-15
Abstract: According to the invention, there is provided a novel soybean variety designated 91Y61. This invention thus relates to the seeds of soybean variety 91Y61, to the plants of soybean 91Y61 to plant parts of soybean variety 91Y61 and to methods for producing a soybean plant produced by crossing plants of the soybean variety 91Y61 with another soybean plant, using 91Y61 as either the male or the female parent.
Patent CA-2735418-A1 (CA)
Inventor: HAUSER RAY L
IPC: A61L15/16
Filed: 2009-08-26
Abstract: A pressure-sensitive adhesive composition and an adherent coating composition are described having a reservoir of medication or other substance and capable of intimate contact with a target area of skin or other tissue, respectively, and rapid conveyance of the medication onto and/or into the target area. The adhesive composition is readily removed from the area of skin using water. Mixtures containing polyvinylpyrrolidone and glycerol have been found to dissolve a large number of medications while producing a self-tackifying, pressure-sensitive adhesive composition, or a brushable and/or sprayable adherent film, depending on the mixture. With the addition of a colorant, the extent of coverage and an estimate of the amount of adherent film delivered may be obtained. Application of the adherent film to provide anti-cancer medication to exposed tissue resulting from tumor resection is also described.
Patent CA-2735573-A1 (CA)
Inventor: MIRSCH JANI
IPC: G09F1/06
Filed: 2009-08-14
Abstract: An information presenting device. The device is arranged to be capable of assuming a first configuration, in which the device is flattened for transport or storage, and of assuming a second configuration, in which the device is extended and hence self-supporting. The device comprises at least two panels 4, made of a rigid material, which are joined together along the respective edges of at least two of the panels such that the device, having assumed the second configuration, forms a hollow cylinder, and at least one locking member 6, arranged between said panels 4, for continuously adjustable locking of the device in said first or second configuration, the locking member 6 comprising a first part 8a and a second part 8b, the first part 8a being slidably connected to the second part 8b and the locking member 6 being self-locking by a friction band coupling formed between contact surfaces of the first part 8a and the second part 8b of the locking member 6.
Patent CA-2735613-A1 (CA)
Inventor: STRAATMAN ANTHONY G
IPC: E03D3/12
Filed: 2011-04-04
Abstract: An apparatus for providing flushing fluid at different rates has a valve for controlling flow through a housing, the valve having a reset area to close the valve, a first bleed valve for constantly providing high pressure fluid to the reset area through a first path, a second bleed valve for providing high pressure fluid to the reset area through a second path, and an actuator. The actuator has a first position in which fluid is prevented from escaping from the second path, a second position in which fluid is allowed to escape from the second path and the second bleed valve is activated, and a third position in which fluid is allowed to escape from the second path and the second bleed valve is deactivated. If the second bleed valve is activated, the first bleed valve causes the reset area to close the valve in a first time period and if the second bleed valve is not activated the first and second valves cause the reset area to close the valve in a second time period wherein the second time period is less than the first time period.