baber/WOPTO huggingface dataset:
Patent CA-2444578-A1 (CA)
Title: Use of hypoxia inducible factor 2alpha for curing neonatal respiratory distress syndrome and as a target for the treatment of pulmonary hypertension
Inventor: COMPERNOLLE VEERLE
IPC: G01N33/74
Filed: 2002-04-24
Abstract: The current invention relates to the field of hypoxia-induced disorders and more specifically to the use of hypoxia inducible factor 2a.alpha. as a targ et in a method for the screening for molecules that can be used for the treatme nt of pulmonary hypertension. The invention further relates to the use of HIF- 2.alpha. and/or of the HIF-2a.alpha. inducible protein VEGF for the treatmen t of neonatal respiratory distress syndrome.
Patent CA-2446401-A1 (CA)
Title: Medical laminate with viral barrier
Inventor: WILBOURN KEITH
IPC: B32B27/12
Filed: 2002-05-01
Abstract: The present invention is directed to a nonwoven fabric construct in the form of a laminate material suitable for medical applications. The laminate includes a nonwoven fabric layer, and first and second polymeric film layers , with the resultant materials exhibiting superior viral protection in accordance with established testing procedures, ASTM F1671. In accordance wi th the present invention, the first and second polymeric film layers are co- extruded and adhered to one surface of the nonwoven fabric layer, with the second polymeric film layer being disposed between the first polymeric film layer and the nonwoven fabric layer. Notably, the first polymeric film layer comprises a blend of between about 0 to 100 % low density polyethylene, and between about 0 to 100 % linear low density polyethylene.
Patent CA-2446751-A1 (CA)
Title: Compositions de kavalactone et leurs methodes d'utilisation
Inventor: MCCLEARY JOEL
IPC: A61P25/02
Filed: 2002-05-13
Abstract: L'invention porte sur des méthodes d'utilisation de compositions bénéfiques pour la santé et en particulier sur des compositions contenant des kavalactones, ainsi que sur leur utilisation et leur préparation.
Patent CA-2451166-A1 (CA)
Title: Method and device for obtaining a sample with three-dimensional microscopy
Inventor: YOURASSOWSKI CATHERINE
IPC: G02B21/06
Filed: 2002-07-01
Abstract: The invention concerns a method for obtaining a sample with three-dimensional microscopy, in particular a thick biological sample, and the fluorescence field emitted by said sample. The invention is characterised in that it comprises: a step of measuring and recording, which consists in measuring and recording sequentially and independently the interferometric signals obtained by digital holography and the fluorescence signals, derived from the sample; a processing step which consists in combining said interferometric signals obtained by digital holography and said thus recorded fluorescence signals so as to reconstruct clear three-dimensional images of the sample itself and of the fluorescence field emitted by the sample at a given time.
Patent CA-2451278-A1 (CA)
Title: Methods and systems for identifying kinases, phosphatases and substrates thereof
Inventor: ORNATSKAIA OLGA
IPC: C12N9/12
Filed: 2002-06-26
Abstract: The instant invention provides methods to determine the phosphorylation status or sulfation state of a polypeptide or a cell using mass spectrometry, especially ICP-MS. The invention also provides methods for identifying a substrate for a kinase using mass spectrometry. This invention further provides business method to conduct a drug discovery business. The invention further provides methods to determine the kinase activity of a peptide, ie., kinase, or the phosphatase activity of a peptide, ie., phosphatase. The invention further provides methods for identifying an inhibitor or an agonist of the kinase activity of a kinase, or an inhibitor or an agonist of the phosphatase activity of a phosphatase. (1) illustrates an autophosphorylation kinase assay determined by P and S centent.
Patent CA-2452844-A1 (CA)
Inventor: BEINBORN MARTIN
IPC: C12N5/06
Filed: 2002-05-03
Abstract: The invention provides methods of identifying receptors having altered signaling. In particular, the invention provides a sensitive dose response assay for the identification of receptors having alterations in ligand dependent or ligand independent signaling.
Patent CA-2453935-A1 (CA)
Title: Improvements in automated bottle inspection apparatus and methods
Inventor: RUTLEDGE THOMAS SCOTT
IPC: G01N21/90
Filed: 2003-12-22
Abstract: Apparatus is provided to conduct an automated foam pick operation on a production bottling line, to withdraw a biased sample of suspect bottles based on abnormal foam characteristics, which sample is then directed to an automated full bottle inspection operation that is set to monitor bottles at a statistically validated sampling rate. A method fur conducting automated foam picking and candling in tandem operations is also provided.
Patent CA-2455401-A1 (CA)
Inventor: DRIGUEZ HUGUES
IPC: C07H17/04
Filed: 2002-07-26
Abstract: The invention concerns disaccharides of formula (I) derived from .alpha.-maltosyl fluoride, wherein R?1¿ and R?2¿ are such as defined in Claim 1. Said disaccharides are useful as glycosyl donors in transglycosylation reactions catalysed by glycoside-hydrolases or in transfer reactions catalysed by transglycosylases during the preparation of oligosaccharides or polysaccharides.
Patent CA-2458048-A1 (CA)
Title: Base frame for fixture
Inventor: CHIU MING-HSIANG
IPC: B25B1/02
Filed: 2004-02-20
Abstract: A base frame for holding fixtures used in woodwork includes an extruded body having a raised top central portion formed into a dovetailed open-topped upper channel, two lowered wing portions located at each lateral side of the upper channel and formed into two symmetrically identical open-topped side channels with a height difference between the tops of the upper and the side channels, and a big-size open-bottomed lower channel formed below said upper channel and said two side channels. With the height difference between the upper and the side channels, two base frames may be perpendicularly connected to each other in the same plane using a U-shaped connecting bracket flush with the top of the upper channel, or superposed with the upper channels facing toward each other by locking inserting blocks in each open-sided channel formed between two side channels at the same side of the two superposed base frames.
Patent CA-2458252-A1 (CA)
Title: Reflector mounting arrangement and method and clip for mounting a reflector in a fluorescent light fixture
Inventor: RABY FREDRICK R SR
IPC: F21V7/10
Filed: 2004-02-17
Abstract: A reflector mounting for fluorescent light fixtures in which a rectangular reflector sheet is formed and held in a trough shape by a series of bracket clips hooked to side edges thereof, the bracket clips having a hole receiving the light tube to thereby hold the reflector in the light fixture.
Patent CA-2459187-A1 (CA)
Title: Sector staging combustor
Inventor: HOWELL STEPHEN JOHN
IPC: F23R3/34
Filed: 2004-02-26
Abstract: A combustor (22) includes outer and inner liners (40,42) joined together by a dome (44) to define a combustor chamber (46). A row of air swirlers (48) is mounted in the dome and includes corresponding main fuel injectors (50) for producing corresponding fuel and air mixtures. Pilot fuel injectors (52) fewer in number than the main injectors (50) are mounted in the dome between corresponding ones of the swirlers (48).  Staged fuel injection from the pilot and main injectors is used for starting the combustor during operation.
Patent CA-2459674-A1 (CA)
Title: Flame barrier cushioning foams and upholstery layer construction incorporating such foams
Inventor: DEERY WILLIAM H
IPC: C08J7/04
Filed: 2004-03-05
Abstract: An upholstery construction for a mattress or an article of furniture includes a flame barrier foam sheet proximate to the back face of a surface fabric layer. The flame barrier foam sheet is formed by coating or impregnating a polyurethane sheet with an aqueous solution of one or more binder(s), such as but not limited to a polyvinyl chloride copolymer or an acrylic latex binder, and one or more flame retardant(s), such as but not limited to aluminum trihydrate or melamine. The flame barrier foam sheet with dried binder(s) and flame retardant(s) not only resists flame ignition but also retains its cushioning properties.
Patent CA-2461722-A1 (CA)
Title: Raccord destine a raccorder des ecarteurs de fenetres a vitres multiples
Inventor: TRPKOVSKI PAUL
IPC: C03C27/06
Filed: 2002-09-20
Abstract: L'invention concerne un raccord (30) pouvant comprendre une cavité centrale supérieure (42), des parois latérales (46, 48) comportant deux espaces (60, 62), des épaulements latéraux (52) comportant des canaux ainsi que des évidements (64). Les raccords de l'invention peuvent également comporter des trous traversant le plancher inférieur de la cavité centrale (42) jusqu'à la partie inférieure du raccord (30) et traversant les canaux inférieurs (76, 78) définis dans le raccord (30). Ces trous peuvent être formés par poinçonnage à travers le matériau d'écarteur, et forment de préférence des parties dentelées permettant la fixation des éléments d'écarteur audit raccord (30). Un produit d'étanchéité peut être injecté à travers les trous poinçonnés et les trous traversants dans le plancher de la cavité centrale dudit raccord. Le produit d'étanchéité injecté peut ainsi couler dans la cavité centrale (42), sur les parois latérales (46, 48) et dans les évidements latéraux (64), et dans les canaux inférieurs (76, 78).
Patent CA-2463523-A1 (CA)
Inventor: GALTEN JEREMY
IPC: B67D7/00
Filed: 2002-10-08
Abstract: A personal hydration system with component connectivity. The hydration system includes a fluid reservoir that may be housed within a pack. Drink fluid is drawn from the reservoir through a drink tube in fluid communication with the reservoir at one end and with a mouthpiece at the other. In some embodiments, the hydration system includes a manually actuated on/off valve downstream from the reservoir and/or a bite-actuated mouthpiece. The hydration system further includes a quick-connect assembly that fluidly interconnects components of the hydration system and which is configured to quickly release, and permit reattachment of, the detached or replacement components. In some embodiments, the hydration system includes a quick-connect assembly that is adapted to selectively couple a bite-actuated mouthpiece and a gas mask adapter to the hydration system's drink tube. In some embodiments, at least a portion, if not the entire, hydration system is formed from a chemically resistant material.
Patent CA-2463899-A1 (CA)
Inventor: GROSS JANE A
IPC: C07K14/47
Filed: 2002-10-16
Abstract: L'invention concerne de nouveaux polypeptides de ligands du facteur de nécrose tumorale, des polynucléotides codant lesdits polypeptides, et des compositions et des méthodes associées. Ces polypeptides peuvent s'utiliser dans des méthodes relatives à la réponse immunitaire ainsi que dans la mise au point de thérapeutiques immuno-régulatrices. L'invention concerne également des anticorps, des protéines de liaisons, des agonistes et des antagonistes des polypeptides de ligands.
Patent CA-2467279-A1 (CA)
Inventor: RUCHELMAN ALEXANDER L
IPC: C07D491/14
Filed: 2002-11-14
Abstract: L'invention concerne des composés de formule (I): dans laquelle A, B, W, Y, Z et R<sb>1</sb> ont les significations définies dans la description et les sels acceptables sur le plan pharmaceutique de ceux-ci. L'invention concerne également des compositions pharmaceutiques comprenant un composé de formule I, des procédés de préparation des composés de formule I, des intermédiaires utiles pour la préparation des composés de formule I et des méthodes thérapeutiques permettant de traiter un cancer au moyen des composés de formule I.
Patent CA-2469555-A1 (CA)
Title: Apparatus and method for sculpting the surface of a bone joint
Inventor: ENGH GERARD A
IPC: A61F2/958
Filed: 2002-06-14
Abstract: The present invention provides a method and device for restoring individual patient joint kinematics using minimally invasive surgical procedures. The instrumentation of the invention sculpts the articular surface of a first bone that normally articulates in a predetermined manner with a second bone. The instrumentation includes a bone sculpting tool and a mount for attaching the tool to the second bone. The implant system is comprised of implants that provide intraoperative surgical options for articular constraint and facilitate proper alignment and orientation of the joint to restore kinematics as defined by the individual patient anatomy.
Patent CA-2470343-A1 (CA)
Title: Compound of mercaptans usable in an ore floating process
Inventor: COMMARIEU ANNIE
IPC: B03D1/004
Filed: 2004-06-09
Abstract: Composition intended for the flotation of ores, comprising: from 70 to 95% of a combination (A) of n-dodecyl mercaptan (or NDM) and of tert-dodecyl mercaptan (or TDM), the NDM/TDM ratio by weight of which is between 0.5 and 1.5, and from 5 to 30% of a product (B) composed of one or more aromatic or aliphatic compounds comprising from 4 to 100 carbon atoms, preferably from 5 to 40, and having one or two -OH groups. Process for the recovery by flotation of metal compounds of value present in ores employing it.
Patent CA-2470573-A1 (CA)
Title: Procede et appareil pour mettre en place un stent dans une lumiere du corps
Inventor: FISCHER KIMBERLY ANN
IPC: A61F2/95
Filed: 2002-12-18
Abstract: L'invention concerne un procédé et un appareil permettant de mettre en place un stent, en particulier, mais non exclusivement, un stent auto-expansible, dans une lumière du corps. L'appareil comprend un tube extérieur présentant une extrémité proximale et une extrémité distale et dimensionné pour contenir un stent à l'état radialement replié, un tube intérieur placé à l'intérieur du tube extérieur, qui présente une extrémité proximale et une extrémité distale, et un élément de maintien qui comprend au moins un ballon gonflable porté par le tube intérieur à l'emplacement du stent chargé. Le ballon peut être gonflé avant la procédure de mise en place de sorte qu'il exerce une pression contre la surface intérieure du tube extérieure, bloquant ainsi le stent en position longitudinale entre le tube intérieur et le tube extérieur. Grâce à cette disposition, le tube extérieur peut coulisser vers l'extrémité proximale pour libérer le stent, ou vers l'extrémité distale, pour ramener le stent dans le dispositif de mise en place, cela sans glissement intempestif du stent.
Patent CA-2471506-A1 (CA)
Title: Components, systems and methods for forming a gasketless seal between components in an ultrahigh pressure system
Inventor: HOPKINS JORDAN J
IPC: F16J15/04
Filed: 2002-12-19
Abstract: Components, assemblies and methods for creating seals in ultrahigh pressure fluid containment systems, are shown and described. Embodiments of the invention allow abutting components of like materials to be compressed against each other without the need of an intermediate gasket or other structure, and reduce relative movement between the abutting parts to increase the useful life of the components. Embodiments of the invention incorporate a first component with a tapered mouth having a curved cross-sectional profile (108, 112), and a complementary component having a mouth with a linear cross-sectional profile (110, 114). The profiles contact each other at a tangential contact angle ranging between 40 and 68 degrees with respect to the radial axis of the components.
Patent CA-2471987-A1 (CA)
Title: Plasma surface processing apparatus
Inventor: KAWASAKI SHINICHI
IPC: C23C16/455
Filed: 2003-10-07
Abstract: In a plasma film forming apparatus, two first electrodes 51 connected to a power source 4 and two grounded second electrodes 52 are arranged in the order of the second electrode 52, the first electrode 51, the first electrode 51 and the second electrode 52. A first flow passage 50a formed between the central first electrodes 51 allows a raw material gas (first gas) for being formed into a film to pass therethrough. A plasma discharge space 50b of a second flow passage formed between the first and second electrodes 51, 52 on the both sides allows an excitable gas (second gas) to pass therethrough, which excitable gas is exited by plasma such that the raw material can be formed into a film, but that the excitable gas itself is merely excited but not formed into a film. Those gases are converged at a crossing part 20c between the first and second flow passages and blown off via a common blowoff passage 25a. By this, the apparatus composing members such as electrodes can be prevented from being adhered with a film.
Patent CA-2473502-A1 (CA)
Title: Complexes based on hetero-cyclobutenyl ligands
Inventor: NAGY SANDOR
IPC: C08F110/02
Filed: 2002-10-17
Abstract: A single-site olefin polymerization catalyst and method of making it are disclosed. The catalyst comprises an activator and an organometallic complex.  The complex comprises a Group 3 to 10 transition metal, M, and at least one anionic heterocyclobutenyl ligand that is bonded to M. Molecular modeling results indicate that single-site catalysts based on anionic heterocyclobutenyl ligands will have advantages compared with the performance of catalysts based on cyclopentadienyl and substituted cyclopentadienyl ligands.
Patent CA-2473568-A1 (CA)
Title: An integrated high-speed serial-to-parallel and parallel-to-serial transceiver
Inventor: ROKHSAZ SHAHRIAR
IPC: H04L25/02
Filed: 2003-01-17
Abstract: A transceiver includes a receiver section and a transmitter section. The receiver section includes a clocking circuit, a serial-to-parallel module, and compensation. The transmitter section includes a clocking circuit, parallel-to-serial module, and compensation. The compensation within the receiver section and transmitter section compensates for integrated circuit (IC) processing limits and/or integrated circuit (IC) fabrication limits within the clocking circuits, serial-to-parallel module, and parallel-to-serial module that would otherwise limit the speed at which the transceiver could transport data.
Patent CA-2477659-A1 (CA)
Title: Flow meter using an expanded tube section and sensitive differential pressure measurement
Inventor: JONES RICHARD T
IPC: E21B47/06
Filed: 2004-08-16
Abstract: A method and apparatus for measuring the flow rate of a fluid within tubi ng disposed within a downhole wellbore. The present invention provides an inver se Venturi meter inserted within tubing with an enlarged inner diameter portio n. Pressure differential is measured between the enlarged inner diameter portio n and another portion of the inverse Venturi meter. Flow rate is determined from t he pressure differential and the density of the fluid.
Patent CA-2480190-A1 (CA)
Inventor: ITSKOVITZ-ELDOR JOSEPH
IPC: A61F2/06
Filed: 2003-03-26
Abstract: The invention is a population of embryonic endothelial cells produced in vitro from human embryonic stem cells. The cells produce platelet endothelial cell adhesion molecule-1 and are vasculogenic. The cells may be combined with a cell support substrate, seeded on a polymer matrix, or combined with a cell-support substrate that is infused into a polymer matrix. The cells may also be injected directly into a tissue site.
Patent CA-2481338-A1 (CA)
Title: Payment terminal device for payment data exchange
Inventor: POLUTNIK ALEKSANDER
IPC: H04W84/04
Filed: 2002-04-16
Abstract: Disclosed is a terminal device (10) for payment data exchange comprising interfaces for coupling to a point of sale devices (26), to a mobile phone (14), and to a payment centre (1). The payment data exchange is performed on two different ways. In a first way from the payment terminal device (10) via the mobile phone (14) and the mobile voice network (5) to the authorisation centre (1) or, vice versa, from the payment centre (1) via the mobile voice network (5) and the mobile phone (14) to the payment terminal device (10), wherein the payment data are transferred between the payment terminal device (10) and the mobile phone (14) on voice information. On the second way the data are transferred directly from the terminal device (10) via e.g. the network (5) to the authorisation centre (1) and, vice versa, from the paymen t centre (1) via the network (5) to the payment terminal device (10).
Patent CA-2481592-A1 (CA)
Inventor: SHILLING MARK W
IPC: E04G21/00
Filed: 2004-09-17
Abstract: A siding support apparatus includes a rigid vertical member having an upper end and a lower end. An anchor block is provided for anchoring the vertical member in parallel spaced relation to a wall to which siding is to be applied.      A plurality of supports are positioned at uniform spaced intervals along the vertical member between the lower end and the upper end.
Patent CA-2481913-A1 (CA)
Inventor: GABRYSCH ALLEN D
IPC: E21B43/10
Filed: 2003-04-04
Abstract: A tool and method for treating an open hole just before expanding a screen (26) into position is described. The swage (16) is hydraulically driven and permits flow through it and out lateral ports (20) to impact the borehole wall. A cup seal assembly (22) below and a packer (14) up above insure that the fluid impacts the borehole wall with sufficient force to dislodge the mud cake. Another feature of the invention is that the surface treatment and screen expansion can be done in one trip. The pressurized fluid that drives the swage (16) also provides the fluid energy to prepare the borehole wall just before the screen (26) is expanded against it.
Patent CA-2483352-A1 (CA)
Inventor: YEH CHIAOLI
IPC: G01N33/574
Filed: 2000-11-16
Abstract: The present invention relates to the treatment of cancer with compounds that inhibit the activity of endo-exonuclease. Endo-exonuclease has been shown to be necessary for the repair of damaged DNA.  Compounds that inhibit the activity of endo-exonuclease have been shown to be particularly effective for treating cancer when used in combination with drugs that induce DNA breaks such as cisplatin and mitomycin C. These compounds have a synergistic effect when used in combination for inhibiting tumour growth. The invention includes pharmaceutical compositions for inhibiting tumour growth comprising a compound that inhibits endo-exonuclease activity. These pharmaceutical compositions preferably include compounds that induce DNA breaks. The invention includes methods of treating cancer with these pharmaceutical compositions and uses of these compositions to treat cancer. The preferred compounds that inhibit the activity of endo-exonuclease have low toxicity. One such compound is pentamidine. The invention also includes a method for diagnosing cancer and monitoring its progression. This aspect of the invention involves isolating serum from a patient; measuring the concentration of endo-exonuclease in said serum and determining whether said concentration is above a predetermined mean.
Patent CA-2483818-A1 (CA)
Title: Procede de production d'une bande de papier
Inventor: THOROE SCHERB THOMAS
IPC: D21F5/04
Filed: 2003-03-20
Abstract: L'invention concerne un procédé pour produire une bande de papier (12) au moyen d'une machine à papier (10) comprenant une caisse d'arrivée de pâtes (14) et une bande transporteuse sans fin (16) au moyen de laquelle la bande de papier est guidée à travers un interstice de pression (22) formé entre un cylindre sécheur (18) et une unité conjuguée (20). La caisse d'arrivée de pâtes est du type multicouche. Au moins deux sortes de pâtes sont acheminées à cette caisse d'arrivée de pâtes multicouche. A la sortie de l'interstice de pression, la bande de papier est enroulée au moyen d'un dispositif d'enroulement (24). Lors de cette opération, la dureté du rouleau formé (80) est de préférence influencée, en particulier commandée et/ou réglée, de façon prédéterminable. L'invention concerne également une machine à papier correspondante.
Patent CA-2485849-A1 (CA)
Title: Colloidal silica binder system
Inventor: KAROGAL NIKHIL
IPC: B23K35/362
Filed: 2004-10-21
Abstract: A welding flux that includes a flux agent, water glass and colloidal compound formed from small particles of silicon dioxide. The welding flux has a very low hygroscopicity, thus is well suited from low hydrogen electrodes.