baber/WOPTO huggingface dataset:
Patent PT-1124831-E (PT)
Inventor: KONSTANTINOVA ROUMIANA GUEORGU
IPC: A61P31/04
Filed: 1999-11-03
Abstract: Sodium salt of 3-(4-cinnamyl-1-piperazinyl)-iminomethyl rifamycin SV was synthesized. The compound shows high activity against Gram-positive and Gram-negative microorganims, Mycobacterium tuberculosis (including atypical and rifampicin resistant) and may be used in the medical practice. The sodium salt has formula (II). The process for preparation of the sodium salt consists of reacting equimolar quantities of 3-(4-cinnamyl-1-piperazinyl)-iminomethyl rifamycin SV and sodium ascorbate with addition of 30% methanol solution of sodium methylate, followed by filtration and removement of the solvent by distillation under reduced pressure. The compound can also be obtained from the sodium salt of 3-formil rifamycin SV, which is reacting with N1-amino-N4-cinnamypiperazin in medium of inert solvent at room temperature.
Patent SG-2387-G (SG)
Title: Sulphonamides, process for their preparation and medicines containing these compounds
IPC: A61K31/185
Filed: 1987-01-15
Abstract: The invention provides sulphonamides of the formula    <IMAGE>  (I) wherein R is a hydrogen atom or a lower alkyl radical; R1 is alkyl, aryl, aralkyl or aralkenyl, the aryl moiety of which in each case can be optionally substituted one or more times by hydroxyl, halogen, trifluoromethyl, lower alkyl or alkoxy or by acyl, carboxy or alkoxycarbonyl; n is 1, 2 or 3; and W is a valence bond or a divalent aliphatic hydrocarbon linkage and the physiologically acceptable salts, esters and amides of such compound. These compounds have excellent pharmacological lipid depressing activity and inhibit thrombocyte aggregation.
Patent SG-81787-G (SG)
Title: 1-b-d-arabinofuranosyl-(e)-5-(2-halogenovinyl) uracil-5'-phosphate, preparation thereof and use thereof
IPC: C07H19/10
Filed: 1987-10-09
Abstract: 1- beta -D-arabinofuranosyl-(E)-5-(2-halogenovinyl)uracil-5'-phosphates of the formula (I):   <IMAGE> (I)  and wherein X is halogen, pharmaceutically acceptable salts thereof, are produced by phosphorylation of the non-phosphorylated precursors of the compounds (I), and are useful as anti-viral agents.
Patent IE-37319-L (IE)
Title: Therapeutic ethers
IPC: A61K31/40
Filed: 1973-02-23
Abstract: 1429852 Amides WELLCOME FOUNDATION Ltd 23 Feb 1973 [25 Feb 1972 28 Feb 1972] 8920/73 Addition to 1380882 Heading C2C [Also in Division A5] The invention comprises amides of the formula wherein L is -Z-A-Z-, where Z is when m is 0 or 1 and X 2 , X 3 and X 4 are H or C 1-3 alkyl; and A is -O.CO.O- or a divalent radical of a dicarboxylic or monocarboxylic acid containing 2 to 14 carbon atoms and having respectively two ester linkages or one ester and one other linkage, to the rest of the molecule, or -CH 2 -, -(CH 2 ) 2 -, or where X and X 1 are H or C 1-3 alkyl ; R and R<SP>1</SP> are H, optionally substituted saturated aliphatic hydrocarbon group having 1 to 7 carbon atoms or an unsaturated aliphatic hydrocarbon group having 2 to 4 carbon atoms; R<SP>2</SP> and R<SP>3</SP> are H, C 1-4 alkyl, R<SP>5</SP>CO, R<SP>6</SP>CO where R<SP>5</SP> and R<SP>6</SP> are H, optionally substituted aliphatic C 1-7 hydrocarbyl, or unsaturated aliphatic C 2-4 hydrocarbyl or together with R and R<SP>1</SP> respectively form C 2-4 alkylene, provided that when L is other than -Z-A-Z- at least one of R<SP>2</SP> and R<SP>3</SP> is, as appropriate, the group R<SP>5</SP>CO or R<SP>6</SP>CO and when one or more of the groups R, R<SP>1</SP>, R<SP>5</SP> and R<SP>6</SP> is a saturated aliphatic C 1-7 hydrocarbyl group substituted by NH 2 , C 1-4 alkylamino or di-(C 1-4 alkyl) amino, acid addition salts thereof. The compounds are obtained by one of the following methods:- (a) reacting in liquid mediums compounds of the Formula III wherein Alk is an alkali metal, D is R or R<SP>1</SP> and E is R<SP>2</SP> or R<SP>3</SP> with compounds of the Formula IV where B is a reactive nucleophilic group or atom; (b) acylating amines of the Formula V wherein at least one of T<SP>1</SP>, T<SP>2</SP>, T<SP>3</SP> and T<SP>4</SP> is H and otherwise T<SP>1</SP> and T<SP>2</SP> are R<SP>1</SP>CO or RCO and T<SP>3</SP> and T<SP>4</SP> are R<SP>2</SP> and R<SP>3</SP> respectively; or (c) reacting in liquid medium compounds of the Formula VII where D is R or R<SP>1</SP> and E is R<SP>2</SP> or R<SP>3</SP> and P is H or an alkali metal with compounds of the Formula VIII wherein G is the moiety of the group A that interconnects the two terminal oxygen atoms thereof. 4<SP>1</SP>-(2-Hydroxyethoxy)acetanilide is made by reacting 4-acetamidophenol with 2-chloroethanol.
[GB1429852A]
Patent IE-890345-L (IE)
Title: Anoxic ammonia oxidation
IPC: C02F3/34
Filed: 1989-02-03
Abstract: A biological denitrification is provided in which ammonium ion is used as an electron donor in the denitrification. The process may advantageously be used under conditions of high ammonium ion concentrations in waste water or to remove ammonium ion from manure, soil or surface water. Microorganisms are described which may be used in these processes.
Patent FI-804047-L (FI)
Inventor: MAYER REINHART
IPC: C08B9/00
Filed: 1980-12-30
Abstract: The invention provides a process for the manufacture of viscoses from hemicellulose-containing cellulose pulps without requiring dialysis equipment. By addition of substances having a cross-linking or blocking action on the active groups of hemicellulose to the pulp before or during steeping it is possible to reduce the use of NaOH and CS2 in the manufacture of viscoses. The viscoses so obtained are distinguished by good filterability and low content of compounds causing formation of H2S in the spinning process.
Patent FI-810643-L (FI)
Inventor: STEINER GERD
IPC: A61K31/55
Filed: 1981-03-02
Abstract: 10-Substituted 5-cyanomethylene-dibenzo[a,d]-cycloheptenes, their pure cis- and trans-isomers, their N-oxides and their pharmaceutically tolerated addition salts with acids, processes for their preparation, therapeutic agents containing these compounds and their use as drugs, especially as sedatives, hypnotics or tranquilizers.
Patent FI-812657-L (FI)
Inventor: DAHLGREN JOENS ARTHUR
IPC: F28F3/08
Filed: 1981-08-27
Abstract: In a plate heat exchanger comprising a plurality of plates (10, 15) placed together to define heat exchange passages (18, 19) between pairs of adjacent plates, the plates being provided with turbulence generating corrugations which on adjacent plates intersect to define supporting areas at which the plates abut each other, at least one plate (10) of one or more pairs of adjacent plates has recessed supporting areas (13) whereby the volume of the passage (18) defined between said plates is reduced.
Patent FI-851046-L (FI)
Inventor: JONCKERS KEES
IPC: C07C273/04
Filed: 1985-03-15
Abstract: A process for the preparation of urea in which a carbamate- and free ammonia-containing urea synthesis solution is formed from carbon dioxide and excess ammonia in a synthesis zone at a pressure of 125-350 bar, at least a portion of the carbamate present in the urea synthesis solution is decomposed in a stripping zone at the pressure of the synthesis zone or at lower pressure by heat supply and countercurrent contact with a stripping gas, the carbamate decomposition products, together with a portion of the excess ammonia and the stripping gas, are removed from the stripping zone as a gas mixture, at least a portion of the gas mixture obtained is condensed in a condensation zone and the stripped urea synthesis solution is processed into a urea solution or solid urea. The process is characterized in that in the condensation zone also at least 30% of the equilibrium amount of urea achievable under the reaction conditions is allowed to form and the carbamate- and urea-containing mixture is supplied to the synthesis zone. By preference, urea formation is continued until 50-80 %, of the way to the equilibrium has been covered.
Patent FI-853624-L (FI)
Inventor: WUEST HANS-HEINER
IPC: C07C65/28
Filed: 1985-09-20
Abstract: 1-substituted tetralins of the formula I   <IMAGE>   where n, R1, R2, R3, R4, R5 and R6 have the meanings stated in the description, and their preparation are described. The compounds are useful for the treatment of disorders.
Patent IE-45636-L (IE)
Title: Testing for corrosion of the internal wall of a metal¹chamber
IPC: G01B21/32
Filed: 1977-07-18
Abstract: Device for the control of corrosion of the inner wall of a metal enclosure. 
[FR2360070A1]
Patent IE-43149-L (IE)
Title: 7-amino-acylamino-3-halo-cephem compounds.
IPC: C07D501/24
Filed: 1976-07-30
Abstract: 7 beta -[D-2-Amino-2-(1,4-cyclohexadienyl)-acetylamino]-3-Hal-3-cephem-4-carb oxylic acids, wherein Hal denotes halogen with an atomic number of up to 35, and pharmaceutically acceptable salts thereof are prepared, which compounds have antibiotic activity.
[US4089955A]
Patent IE-831715-L (IE)
Title: Analgesic and anti-inflammatory compositions
IPC: A61K31/485
Filed: 1983-07-21
Abstract: Novel analgesic and anti-inflammatory compositions of matter for use in eliciting an analgesic or anti-inflammatory response, said compositions comprising caffeine together with a selected non-narcotic analgesic/nonsteroidal anti-inflammatory drug or a selected narcotic analgesic, or both. When used in combination with the selected drugs, caffeine enhances the analgesic or anti-inflammatory response and also hastens its onset.
[GB2134786A]
Patent IE-871861-L (IE)
Title: Diphosphonic acids
IPC: C07F9/38
Filed: 1987-07-10
Abstract: The present invention provides disphosphonates of the general formula:   <IMAGE> (I)  wherein R1 is a straight-chain or branched, saturated or unsaturated aliphatic hydrocarbon radical of 1-9 carbon atoms which is optionally substituted by phenyl or cyclohexyl, R2 is cyclohexyl or cyclohexylmethyl, benzyl or a straight-chained or branched, saturated or unsaturated aliphatic hydrocarbon of 4 to 18 carbon atoms which is optionally substituted by phenyl or oxygen wherein the oxygen can be esterified or etherified, R3 is hydrogen or a straight-chain or branched alkyl of 1-4 carbon atoms, X is a straight-chain or branched alkylene chain of 1-6 carbon atoms and Y is hydrogen, hydroxyl or an amino group optionally substituted by alkyl radicals of 1-6 carbon atoms; as well as the pharmacologically acceptable salts thereof. The present invention also provides processes for the preparation of these diphosphonic acid derivatives and pharmaceutical compositions containing them for the prophyllaxis treatment of diseases or disturbances of calcium metabolism such as osteoporsis, Pagets disease, Bechterew's disease, bone metastases, urolithiasis, heterotropic ossifications, rheumatoid arthritis, osteoarthritis and degenerative arthrosis.
Patent IE-40024-L (IE)
Title: Application of strip material
IPC: B31B50/72
Filed: 1974-09-09
Abstract: An apparatus for adhering strips of predetermined length that previously have been severed from a running web of material to folded blank boxes which includes cutting the strips to length, advancing them by a conveyor seriatim past an adhesive activation station and then coordinating the leading edge of the strip with the arrival of the folded blank box at a roller assembly station where the strip is secured to the box and then discharged.
[US3955481A]
Patent IE-45708-L (IE)
Title: Zinc bacitracin additive
IPC: A23K20/195
Filed: 1977-10-16
Abstract: A zinc bacitracin composition for use as a feed supplement which possesses improved stability to heat, mechanical mixing and moisture when used in substantially dry animal feeds. Zinc bacitracin is precipitated by the addition of zinc cations, as in the range of between 0.5 to 0.7 g Zn++/g bacitracin to a bacitracin fermentation broth, and then concentrated to 25 to 35% dry matter. Finely divided carrier material, such as calcium carbonate, is then added to the extent of 50 to 100 weight percent based on the dry matter, and the mixture is agitated to get a uniform mix. The uniform mixture is then spray dried to produce substantially spherical particles of the zinc bacitracin composition.
[US4096246A]
Patent IE-802210-L (IE)
Title: Simultaneous analysis apparatus
IPC: G01N33/49
Filed: 1980-10-24
Abstract: Analysis apparatus which uses a solid reaction support designed to hold successively a quantity of first reagent such as a biological liquid which contains the substance to be analysed, and then a quantity of second reagent which contains a protein on which is fixed a biological indicator. The apparatus is constituted by an analysis rotor (1 ) which includes firstly a plurality of peripheral cells (2) each of which contains said reaction support (3) and secondly means which allow a washing liquid to be conveyed towards each cell, each of said cells (2) being provided with a peripheral orifice (7) for removing liquid and having an upper portion provided with a reagent inlet orifice (8) and a lower portion which accommodates said reagent.
[US4314968A]
Patent IE-822376-L (IE)
Title: Clip connector
IPC: H01R13/648
Filed: 1982-09-30
Abstract: 1. An integrally moulded clip connector comprising a moulded case (4) provided with securing clips (41) and release wings (42), a plurality of conductors (2) one of which is connected to a resilient and conducting grounding strip (5), and the others are connected to resilient and conducting elements (1) nipping with a given pressure stripped electric conductors of dimension d housed in electricity distribution ducts, said resilient and conducting elements (1) having the form of a U whose legs are spaced apart by a value e less than d, connector in which said resilient and conducting elements (1) each consist of a U-shaped element with jointing legs whose legs were spaced apart by a value e during moulding of the case.
[EP0077242A1]
Patent IE-822576-L (IE)
Title: Disconnectable electromagnetic jack
IPC: F02M31/06
Filed: 1982-10-27
Abstract: The present invention relates to a disconnectable electromagnetic eccentric actuator for controlling a mobile member for automatically adjusting a machine. The eccentric actuator comprises a ferromagnetic drive force transmitting screw and nut (of larger diameter than the screw) to convert into axial movement the cycloidal rolling movement of the screw relatively to the wall of the fixed nut, the latter itself forming an integral part of means for converting an electromotive force into a displaceable magnetomotive force whose resultant generated flux causes mutual adhesion, as well as said cycloidal relative movement of the screw and the nut. The screw disconnects when supply current is cut off. The invention is applicable to the automatic control of a flap for regulating the temperature of the intake air in heat engines.
[US4482828A]
Patent IE-843221-L (IE)
Title: Non-aqueous ivermectin formulation
IPC: A61K47/00
Filed: 1984-12-14
Abstract: Ivermectin, an antiparasitic agent which is insoluble and unstable in water, and other avermectin and milbemycin compounds, are formulated in glycerol formal and propylene glycol or in water and propylene glycol. These liquid formulations are suitable for parenteral administration for the treatment of parasitic infections and demonstrate improved efficacy and a broadened spectrum over previous formulations.
Patent NO-802727-L (NO)
Inventor: TILMAN PAUL ARTHUR
IPC: B65D33/24
Filed: 1980-09-12
Abstract: A closure strip (1) which incorporates a profiled closure element for use in resealable or reclosable bags is provided with a channel (4) in its surface which contacts a bag forming substrate material (6) for receiving adhesive (5). The presence of the channel ensures that a suitable thickness of adhesive is present at the time of bonding of the closure strip to the substrate. The invention also provides a method of making bag forming material by use of such a closure strip.
Patent NO-820811-L (NO)
Inventor: BRINT NORMAN TREVOR
IPC: F41C7/00
Filed: 1982-03-12
Abstract: A firearm especially for firing large calibre rounds such as rubber bullets and having a magazine (103) in which a plurality of rimmed rounds may be stacked in contact with one another, the magazine (103) being rechargeable at any stage of depletion. The firearm includes a catch (118) mechanism which locks a round in the breech on insertion, permits the rim of a round to ride forward over the rim of a previously-inserted round without fouling, and the extraction of a spent round rearwardly without its rim fouling a previously-inserted round. Mechanism for firing, automatic feed, and automatic extraction and ejection of spent rounds is described.
Patent NO-842064-L (NO)
Inventor: FALCH ERIK
IPC: C07D498/04
Filed: 1984-05-23
Abstract: Tetrahydroisoxazolol[4,5-c]pyridine derivatives of the formula: 
<CHEM>
 individual isomers and pharmaceutically acceptable acid addition salts thereof, wherein R1 is hydrogen, alkyl or phenyl-lower alkyl, in which the phenyl group may be substituted with halogen, lower alkyl or lower alkoxy; R2 is alkyl, alkenyl, alkynyl or phenyl-lower alkyl, in which the phenyl group may be substituted with halogen, lower alkyl or lower alkoxy; and R4 is hydrogen or alkyl. 
<??>The compounds are prepared by different methods. 
<??>The compounds have been found to posses strong acetylcholine agonistic activity in pharmacological tests and having few undesired side effects. 
<??>Pharmaceutical compositions of said compounds, and methods for the treatment of diseases involving acetylcholine malfunction are described.
Patent NO-850678-L (NO)
Inventor: SCHOU HERBERT WILLIAM DOECKER
IPC: A21D2/36
Filed: 1985-02-20
Abstract: A finely divided composition prepared by heating and extrusion of a mixture of a cereal flour or meal or starch on the one hand and a vegetable fibrous material on the other hand is included in the mixture from which bread dough for rye bread or coarse bread types based on rye or wheat meal combined with other cereal meals or flours is made. The composition exerts the same effect as the precooked starch used in the known art, but results in improved sliceability, improved taste and a more pleasant colour, together with a better gas retention and a better machinability. A preferred composition is made from about 40% of rye meal and about 60% of wheat bran. The extrusion is performed under conditions under which a certain degree of precooking of the starch or the cereal component of the composition will take place, preferably at such a temperature that a certain degree of roasting of the product will take place, such as a temperature of 150-180 DEG C. The extrusion results in expanded, relatively crisp granules, which are then comminuted in a hammer mill or disc mill into the final composition.
Patent NO-853773-L (NO)
Inventor: SALEEB FOUAD ZAKI
IPC: B01J20/04
Filed: 1985-09-25
Abstract: A carbon dioxide sorbent is disclosed which comprises calcium hydroxide at a level of from 70 to 95% by weight based upon the total dry weight of the sorbent, sodium hydroxide, potassium hydroxide or admixture thereof at a level of from 5 to 15% by weight, optionally calcium chloride at a level of from 5 to 15% by weight and less than 1.5% moisture. Also disclosed is a method for packaging coffee utilizing the carbon dioxide sorbent.
Patent NO-853880-L (NO)
Inventor: OJALA LAURI
IPC: A01J5/04
Filed: 1985-10-01
Abstract: A means for measuring milk drawn with a pipe milking machine, particularly in systems according to the Patent F1 65697, in which the milk is pumped from a centrepiece (2) by a vacuum pipe (4) with the aid of a pump (6) into a milk pipe (12) under normal pressure. The pump of said Patent operates under control by the pulsator of the milking machine. Hence follows that the piston strokes are different in length, and therefore their number does not give the exact milk quantity. As taught by the present invention, the operation of the pump takes place under control by vacuum so that the extreme positions of the pump's piston control a control valve (24, 24'). The control valve admits the vacuum alternatingly on either side (8, 10) of the upper part of the pump piston (7). The piston stroke length thus obtained is accurate enough, whereby the piston stroke with the aid of the readings of a counter (25) yields an accurate enough milk quantity measuring result. The means also enables a sample quantity of desired magnitude to be taken.
Patent NO-880191-L (NO)
Inventor: JOSEFSSON BJOERN
IPC: C07D207/404
Filed: 1988-01-18
Abstract: A new chiral reagent of formula (I), wherein X is halogen, an azide group or a succinimidyl group and wherein R is an alkyl group or a trifluormethyl group. The invention further relates to a method for derivatization, determination and preparative resolution of primary and secondary amino-containing compounds. The method comprises the steps of derivatizing the amino function by said reagent to form diastereomeric carbamates, which are determined by e.g. fluorimetry or absorptiometry after separation by liquid chromatography.
Patent NO-885338-L (NO)
Inventor: MILLER KENNETH A
IPC: C06B21/00
Filed: 1988-11-30
Abstract: A method is described of manufacturing emulsion explosives comprising (a) forming an oil-continuous emulsion at an elevated temperature, (b) incorporating a density reducing agent into the emulsion to sensitize it, (c) packaging the sensitized emulsion into a flexible tubing of desired diameter, (d) cooling the loaded tubing to a desired temperature, and (e) overwrapping the loaded tubing with an additional packaging material. After cooling, and before overwrapping, the continuous tubing can be cut into individual tubes of desired length, so that it is the individual tubes which are subsequently overwrapped.
Patent NO-892829-L (NO)
Inventor: JOVERO OLLI
IPC: B29C33/56
Filed: 1989-07-07
Abstract: The present invention concerns a metal-coated plastic product mould and a procedure for producing the same. The plastic product mould comprises a metallic mould surface blank (30) produced by deep drawing, liquid bulging or explosion shaping, or other thin-sheet technique, attached to a backing layer (40), the shape thereof being consistent with the shape of the mould surface blank (30).
Patent NO-893441-L (NO)
Inventor: BURLEY RICHARD
IPC: C08B3/06
Filed: 1989-08-28
Abstract: A process for making cellulose acetate from wood pulp takes wet wood pulp and instead of converting it into dry pulp sheet which is the usual feedstock for acetate, dries and mechanically separates the pulp into a cellulose flock using a pin mill through which a hot drying gas is passed. Deactivation of the cellulose is avoided by control of the drying gas exit temperature to 80 DEG C to 95 DEG C and of the moisture content of the cellulose flock to 4 to 15% by weight. The flock produced may be acetylated directly without any need for reactivation treatments additional to the normal activation with acetic acid.
Patent NO-902391-L (NO)
Title: Impregnert engangsklut for rensing og vedlikehold av harde overflater.
Inventor: BRUNET PHILIPPE
IPC: A47L/
Filed: 1990-05-30
Abstract: Impregnert engangsklut som består av et vevd eller ikke-vevd hydrofilt materiale, fremstilt ved våt- eller tørr-metode, og med en maksimal absorpsjonskapasitet for vann på minst 200 vekt-% i tørr tilstand, impregnert med en vandig blanding til et nivå som ikke overstiger 50% av den maksimale absorpsjonskapasitet,at den vandige blanding finnes i form av en vandig oppløsning som inneholder minst 4 vekt-%, basert på den totale vekt av den vandige blanding, av minst ett løsningsmiddel som er blandbart med vann, og minst én mineralsyre eller organisk syre i en mengde som er tilstrekkelig til å gi oppløsningen en sur pH.