baber/WOPTO huggingface dataset:
Patent AU-2870392-A (AU)
Title: Novel potent inducers of terminal differentiation and methods of use thereof
IPC: A61K31/16
Filed: 1992-10-05
Abstract: The present invention provides the compound having the structure: wherein each of R1 and R2 are independently the same as or different from each other; when R1 and R2 are the same, each is a substituted or unsubstituted arylamino, cycloalkylamino, pyridineamino, piperidino, 9-purine-6-amine, or thiozoleamino group; when R1 and R2 are different, R1=R3-N-R4, wherein each of R3 and R4 are independently the same as or different from each other and are a hydrogen atom, a hydroxyl group, a substituted or unsubstituted, branched or unbranched alkyl, alkenyl, cycloalkyl, aryl, alkyloxy, aryloxy, arylalkyloxy, or pyridine group, or R3 and R4 bond together to form a piperidine group and R2 is a hydroxylamino, hydroxyl, amino, alkylamino, dialkylamino or alkyloxy group; and n is an integer from about 4 to about 8. The present invention also provides a method of selectively inducing terminal differentiation of neoplastic cells and thereby inhibiting proliferation of such cells. Moreover, the present invention provides a method of treating a patient having a tumor characterized by proliferation of neoplastic cells. Lastly, the present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically acceptable amount of the compound above.
Patent AU-2912592-A (AU)
Title: Benzimidazole anthelmintic agents
IPC: C07D417/12
Filed: 1992-11-04
Abstract: PCT No. PCT/EP92/02564 Sec. 371 Date May 9, 1994 Sec. 102(e) Date May 9, 1994 PCT Filed Nov. 4, 1992 PCT Pub. No. WO93/10101 PCT Pub. Date May 27, 1993.Benzimidazole anthelmintic agents of the formula (I) and their non-toxic salts, wherein R1, which is in the 5(6)-position, is either H or certain stated substituents, "alk" is a methylene or ethylene group; R2 is cyano, C1-C4alkenyl, C2-C4 alkynyl, C2-C4alkanoyl, C1-C4alkoxy, C2-C4alkenoxy, aryl, heteroaryl, aryl-(C1-C4alkoxy) or heteroaryl-(C1-C4alkoxy), in which "aryl" means phenyl optionally substituted by 1 to 3 substituents each independently selected from halo, C1-C4alkyl, C1-C4alkoxy, C1-C4alkylthio, C1-C4alkylsulphinyl, and C1C4alkylsulphonyl in which "heteroaryl" means thienyl, furyl or pyridininyl all optionally substituted by 1 to 3 substituents each independently selected from halo, C1-C4alkyl, C1-C4alkoxy, C1-C4alkylthio, C1-C4alkylsulphinyl and C1-C4alkylsulphonyl; and R3 is a C1- C4alkyl group. The anthelmintic agents (I) are, unexpectedly, active topically and parenterally, and are thus suitable for spot-on, pour-on, or parental (especially in tramuscular) administration.
Patent AU-2943292-A (AU)
Title: Self-extinguishing polymeric compositions
IPC: B65G17/36
Filed: 1992-11-13
Abstract: Self-extinguishing thermoplastic polymeric compositions comprising a phosphorus derivative and condensation compounds obtained by means of the polymerization of polyaminic mixtures essentially constituted by derivatives of 2,4,6-triamino-1,3,5-triazine, having the general formula (I): <CHEM> with aldehydes, preferably formaldehyde. p
Patent AU-3009399-A (AU)
Title: Mu-1, member of the cytokine receptor family
Inventor: DONALDSON DEBRA
IPC: A61K38/17
Filed: 1999-03-17
Abstract: Polynucleotides encoding the MU-1 hematopoietin receptor superfamily chain and fragments thereof are disclosed. MU-1 proteins and methods for their production are also disclosed.
Patent AU-3042601-A (AU)
Title: Therapeutic morpholino-substituted compounds
Inventor: ROBERTSON ALAN D
IPC: C07D311/22
Filed: 2001-01-24
Abstract: Morpholino-substituted pyridopyrimidine, quinolone, and benzopyranone derivatives inhibit phosphoinositide (PI) 3-kinase, an enzyme that regulates platelet-adhesion processes. As a cansequence, the compounds in question have anti-thrombotic activity, as well as other pharmaceutical properties. PI 3-kinase generates 3-phosphorylated PI second messengers which stimulate platelet adhesion under blood-flow conditions. Because platelet adhesion is a necessary step in the formation of a thrombus, inhibition by these compounds of PI 3-kinase under such conditions inhibits or prevents thrombus formation. The compounds are useful in treating PI 3-kinase-dependent conditions including cardiovascular diseases such as coronary artery occlusion, stroke, acute coronary syndrome, acute myocardial infarction, vascular restenasis, atherosclerosis, and unstable angina; respiratory diseases such as asthma, chronic obstructive pulmonary diseases (COPD), and bronchitis; inflammatory disorders; neoplasms including cancers such as glioma, prostate cancer, small cell lung cancer, and breast cancer; and diseases linked to disordered white blood cell function, such as autoimmune and inflammatory diseases.
Patent AU-3164295-A (AU)
Title: Oxime ethers and their use as pesticides
Inventor: PFIFFNER ALBERT
IPC: A01N43/08
Filed: 1995-07-21
Abstract: Compounds of formula I are suitable for controlling and preventing infestation by microorganisms, insects and acarina on plants    <IMAGE>  (I)  and their possible isomers and mixtures of isomers, wherein a) X is CH2F or CHF2,  Y is CH and  Z is OCH3, or b) X is CH2F or CHF2,  Y is a nitrogen atom and  Z is OCH3 or NHCH3, and wherein R1 and R2 are each independently of the other hydrogen, cyano, C1-C12alkyl, halo-C1-C12alkyl, C2-C12alkenyl, C2-C12alkynyl, C3-C6cycloalkyl, cyclopropylmethyl, C1-C4alkoxy, C2-C12alkoxyalkyl, C1-C4alkoxycarbonyl, C1-C4alkylthio, C2-C5alkylthioalkyl; or an unsubstituted or mono- to tri-substituted ring having not more than 15 ring carbon atoms that may be multi-membered and that contains from 0 to 3 hetero atoms N, O or S, it being possible for that ring to be bonded via an aliphatic bridge having not more than 4 carbon atoms and/or via CO, oxygen or sulfur, as desired; or wherein R1 and R2 together with their common carbon atom form an unsubstituted or mono- to tri-substituted ring having not more than 15 ring carbon atoms that may be multi-membered and that contains from 0 to 3 hetero atoms N, O or S. They can be used in the form of commercially customary formulated compositions.
Patent AU-3255701-A (AU)
Title: Controlled urinary incontinence treatment
Inventor: FORSELL PETER
IPC: A61F2/02
Filed: 2001-02-08
Abstract: A urinary incontinence treatment apparatus comprises a restriction device implantable in a patient, for engaging the urethra or urine bladder to form a restricted urine passageway in the urethra or urine bladder. The restriction device is operable by an implantable operation device to change the restriction of the urine passageway. A control device is provided for controlling a source of energy, which may or may not be implanted, from outside the patient's body, to release energy for use in connection with the operation of the restriction device, i.e. to power the operation device.
Patent AU-3298100-A (AU)
Title: Immunostimulant bacterial membrane fractions in cancer treatment
Inventor: LIBON CHRISTINE
IPC: A61K35/74
Filed: 2000-03-15
Abstract: The invention concerns the use of a membrane fraction of gram-negative bacteria, in particular Klebsiella pnemoniae for preparing a pharmaceutical composition that is immunostimulant and/or capable of inducing an antitumoral immune response, designed in particular for treating and preventing cancers. The invention further comprises methods for preparing said membrane factions and pharmaceutical compositions containing them, in particular combined with anticancer compounds.
Patent AU-3307100-A (AU)
Title: Crosslinkable coating compositions
Inventor: OVERBEEK GERARDUS CORNELIS
IPC: C09D133/06
Filed: 2000-03-17
Abstract: An aqueous crosslinkable coating composition comprising i) an autoxidisably crosslinkable polymer, ii) a not autoxidisably crosslinkable vinyl polymer bearing carbonyl groups and iii) carbonyl-reactive groups to crosslink the vinyl polymer.
Patent AU-3418000-A (AU)
Title: Covalently closed immunostimulating nucleic acid molecule
Inventor: JUNGHANS CLAAS
IPC: A61P37/04
Filed: 2000-02-24
Abstract: Short deoxyribonucleic acid molecules that are partially single-stranded, dumbbell-shaped, and covalently closed, which contain one or more unmethylated cytosine guanosine motif (CpG motif) and exhibit immunomodifying effects. Such molecules can be used for immunostimulation applications in humans or vertebrates.
Patent AU-3512889-A (AU)
Title: New heparin derivatives and process for their preparation
Inventor: PIANI SILVANO
IPC: C08B37/10
Filed: 1989-05-24
Abstract: New heparin derivatives having antithrombotic activity, also endowed with reduced hemorrhagic and anticoagulant effects, obtained by treating in a basic medium heparins of various origin, optionally in the presence of alkali metal salts and of a reducing agent. The heparin derivatives obtained through this treatment show peculiar chemico-physical characteristics, like new signals at about 53 and 54 p.p.m. in the <1><3>C-NMR spectrum and a raise of the specific rotatory power, compared to that of the starting heparins, to values between +50 DEG  to +90 DEG . Said structural modifications produce an improvement of the biological properties of the heparin, substantially keeping the antithrombotic activity while diminishing the hemorrhagic effect in vivo and the anticoagulant activity in vitro.
Patent AU-3777397-A (AU)
Title: Frequency dividing circuit
Inventor: FOGG ANDREW
IPC: H03K23/66
Filed: 1997-08-01
Abstract: A frequency-dividing circuit comprises a digital accumulator capable of performing signed arithmetic and means for adding of a predetermined numerator to the content of the accumulator. Means are provided for subtracting a predetermined denominator from the content of the accumulator and further means detect if the value held in the accumulator has become zero or negative and establishing a delay setting value dependent upon the held value. Further means convert the delay setting value into a time delay inversely proportional to the magnitude of the delay setting value and the yet further means change the state of a digital output signal on expiry of the said time delay. A corresponding method is also disclosed.
Patent AU-4259599-A (AU)
Title: Method and device for preserving snow
Inventor: MORENT RALF
IPC: A63C19/10
Filed: 1999-05-11
Abstract: The invention relates to a method and device for preserving snow. A cooling mat device (2) is laid out on predetermined areas of a subbase (1) on which snow should be preserved. A coolant is fed to said cooling mat device via a coolant supply line (21), and the coolant is removed via a coolant return line (22).
Patent AU-4270096-A (AU)
Title: High purity N-(4-(N,N-bis(2-iodoethyl)amino)phenoscycarbonyl)-l-glutamic acid
Inventor: HEATON DAVID WILLIAM
IPC: C07C269/06
Filed: 1995-12-21
Abstract: PCT No. PCT/GB95/02997 Sec. 371 Date Jun. 23, 1997 Sec. 102(e) Date Jun. 23, 1997 PCT Filed Dec. 21, 1995 PCT Pub. No. WO96/20169 PCT Pub. Date Jul. 4, 1996A new salt of a prodrug useful in antibody directed enzyme prodrug therapy (ADEPT) is disclosed. A hydrogen iodide salt of the prodrug N-(4-[N,N-bis(2-iodoethyl)amino]phenoxycarbonyl)-L-glutamic acid is prepared which can be obtained in crystalline form. Preparation of the crystalline form of the prodrug enables preparation of the prodrug in highly pure form.
Patent AU-4272396-A (AU)
Title: Connecting element for wood-concrete composite structure
Inventor: KUTTEL RICHARD
IPC: E04B5/23
Filed: 1996-01-10
Abstract: The invention concerns a novel solution to the problem of providing a connection in wood-concrete composite structures. Wood-concrete connecting elements of this type can be used in the construction of new buildings or the renovation of old ones, and in bridge building. The novelty of the connecting element lies in the principle of the transmission of shearing forces between the wood (4) and concrete (5). The shearing forces are transmitted by a larger rod-shaped connecting element (1) via a plate (3) to a number of smaller rod-shaped connecting elements (2).
Patent AU-4384697-A (AU)
Title: The production of solid pharmaceutical forms
Inventor: BREITENBACH JORG
IPC: A61K9/20
Filed: 1997-09-11
Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.
Patent AU-4539401-A (AU)
Title: Endovascular device having a stent
Inventor: GREENBERG ROY K
IPC: A61F2/82
Filed: 2001-03-02
Abstract: A stent (10,20,30,40,50,58,60,80,90,100,150,254,256,300) having an inflatable member or a plurality of members affixed directly thereto. One type of inflatable member, or pair or plurality of members, may be affixed to the outer stent surface to expand upon inflation to seal against the vessel wall, and optionally to each other as well, and may be annular (14,18,20,42,46,82,94) or spirally (22,24,26,84) or asymmetrically (32,34,36) configured. In another embodiment a member (304), or pair of opposed members (306), can be affixed to the inner stent surface and used to occlude the lumen upon inflation. The device of the present invention can also be utilized with conventional stent grafts (152) to protect branch vessels that are involved in the aneurysm span.
Patent AU-4612997-A (AU)
Title: Device and method for comminution
Inventor: SAND JOHN
IPC: B02C13/16
Filed: 1997-10-16
Abstract: A device for comminuting raw materials like glass, rock, rubber buffings and the like, is disclosed. Raw material is propelled outwardly towards violent impact against a circular wall and then lifted by rapidly rising air for separation and possible return for further propelling outwardly towards impact against the circular wall.
Patent AU-4642900-A (AU)
Title: Displaying data on lower resolution displays
Inventor: KETRENOS JAMES P
IPC: G09G5/391
Filed: 2000-04-12
Abstract: Data intended to be displayed on a higher resolution display such as a non-interlaced display used as a computer monitor may be converted for display on a lower resolution display such as an interlaced display. The conversion may be done in a way that preserves the intended frame format while enhancing readability. For example, in one embodiment, the frames intended for non-interlaced display may be preserved in size for display in the same frame format on a lower resolution interlaced display. Local magnification may be selectively implemented for particular regions to enhance the readability of those regions. Upon selection, such local magnification may provide pixel loss and color corrections in addition to local magnification. In this way the frame format may be preserved while enhancing readability.
Patent AU-4716696-A (AU)
Title: On-load tap changer of a step switch
Inventor: NEUMEYER JOSEF
IPC: H01H25/06
Filed: 1996-01-31
Abstract: PCT No. PCT/EP96/00400 Sec. 371 Date Mar. 25, 1997 Sec. 102(e) Date Mar. 25, 1997 PCT Filed Jan. 31, 1996 PCT Pub. No. WO96/30922 PCT Pub. Date Oct. 3, 1996An on-load tap changer of a step switch has a force-storage unit which has a charging slide continuously movable by a bidirectionally rotatable drive shaft and an output part that when tripped suddenly follows the movement of the charging slide and rotates a switching shaft. Respective switches for each phase are each actuatable by respective actuating elements that coact with edges of respective concentric cams rotatable by the switching shaft. An axially movable switching unit is mounted on the switching shaft and the switching unit carries cam disks for actuating the switches, each cam disk being subdivided into an upper and a lower subdisk with different shapes. The switching unit is movable in a direction dependent on the rotation direction of the drive shaft into an upper or a lower position. In the upper position of the switching unit all of the lower cam subdisks and in the lower position of the switching unit all of the upper cam subdisks engage the actuating elements to actuate the respective switches.
Patent AU-4767296-A (AU)
Title: Personal care compositions and wipe products containing the compositions
Inventor: BLIESZNER KATHLEEN CLARE
IPC: A61K8/02
Filed: 1996-01-24
Abstract: Personal care compositions that are especially suitable for personal cleansing of the perineal area and protection against perineal dermatitis are disclosed. Preferred compositions include water, dimethicone, a polymeric emulsifier and optionally a water-soluble polyol, a pH-adjusting agent, an anti-microbial agent, and a chelating agent. Also disclosed are disposable wipe products containing a nonwoven or other substrate impregnated with the composition.
Patent AU-4919290-A (AU)
Title: Derivatives of pyrimidinyl-piperazinyl-alkyl azoles with anxiolytic and/or tranquilizing activity
Inventor: PINOL AUGUSTO COLOMBO
IPC: C07D403/12
Filed: 1990-02-07
Abstract: The invention relates to heterocyclic compounds which correspond to the general formula I 
<IMAGE>
 in which
 R1 represents a hydrogen atom or a halogen,
 n can have the values 1 to 6, and
 Het represents an azole or one of its derivatives, chosen from imidazole, indazole, tetrahydroindazoles, pyrazole and pyrazoline, which may be represented by the general formula II 
<IMAGE>
 in which
 A and B, which are always different, represent a carbon atom or a nitrogen atom, the dotted line indicating the possible presence of a double bond between positions 4 and 5, and
 R2, R3 and R4, which may be identical or different and can also form a part of another ring, aromatic or otherwise, represent a hydrogen atom, a halogen, a lower alkyl radical, a nitro radical, a hydroxyl radical, an oxo radical, an alkoxy radical, a cyano radical, a carboxyl radical, a carboxamido radical, an alkyl carboxylate radical, an aryl or substituted aryl radical, a sulphonic radical, a sulphonamido radical, substituted or otherwise on the amino group, or an amino or substituted amino radical of general formula III 
<IMAGE>
 in which
 R5 and R6, which may be identical or different, represent a hydrogen atom, an alkyl radical, an aryl radical, a heteroaryl radical, an alkenyl radical, an alkylcarboxy radical, an arylcarboxy radical, an alkylsulphonyl radical or an arylsulphonyl radical.
Patent AU-4947890-A (AU)
Title: Television transmission system compatible with conventional television standards
Inventor: HABERMANN WERNER
IPC: H04N7/00
Filed: 1989-12-07
Abstract: In the system disclosed, scanning is carried out on the image source side with a frame corresponding to an enlarged 16:9 picture ratio. On the emitter side, every fourth line of the picture signal is first isolated and the remaining lines are compressed. A 4:3 standard receiver reproduces a corresponding image in the "letter box" format. The 16:9 receiver should reconstruct the original picture signal. First solution: the isolated lines are expanded for the duration of a complete picture, modulated to a second picture carrier at the upper end of the transmission channel outside the standard intermediate frequency resonance curve, and then demodulated, expanded and reintroduced into the 16:9 receiver. Second solution: analog-coded line difference signals in the level between the black and synchronization pulses are transmitted in the freed spaces at the upper and lower edges of the picture, decoded in the 16:9 receiver and reused. Third solution: additional digital data, e.g. motion vectors, are transmitted in the spaces freed at the upper and lower edges of the picture, and used by the 16:9 receiver to interpolate the missing lines. Application to television receiving sets with 4:3 and 16:9 picture ratio.
Patent AU-5022699-A (AU)
Title: Spray cleaner for interior surface of pipeline
Inventor: MACNEIL GERARD
IPC: B08B9/049
Filed: 1999-07-27
Abstract: This application discloses an automated apparatus for cleaning the interior surface of a pipe. The device includes a vehicle which propels itself down the inside of the pipe. A cleaning system is fixed to the vehicle and uses arms to reach the walls of the pipe. At the end of each arm sits a spray nozzle assembly equipped with spray nozzles. The spray nozzle assembly rotates or oscillates to spray clean the pipe surface. The arms and spray nozzle assembly interchange with other such cleaning systems depending on the shape or type of pipe and the desired cleaning technique. The apparatus is tethered to a source of fluid under pressure and a power source both of which are located off-board the apparatus at a remote location. An operator supervises the device's operation, controlling the speed and direction of travel of the vehicle, the speed and direction of oscillation and rotation of the cleaning system, and the fluid pressure delivered by the spray nozzles.
Patent AU-5061090-A (AU)
Title: Aids therapy
IPC: A61K38/00
Filed: 1990-03-02
Abstract: The administration of CD4, particularly soluble CD4 and its derivatives, and the associated administration of immunogenic HIV-1 protein or vaccine material provides a useful procedure for the prevention and/or treatment of HIV-1 infections.
Patent AU-5202999-A (AU)
Title: Staged rotisserie
Inventor: MCCONNELL JAMES W
IPC: A47J37/04
Filed: 1999-05-20
Abstract: A staged rotisserie for cooking poultry includes a housing having an inlet end and an outlet end and a plurality of discrete heating stations spaced within the housing between the inlet end and the outlet end. A plurality of poultry spits are moved through the housing, each spit supporting a poultry thereon. An admission mechanism is provided for controlling admission of spits into the housing. An advancement and driving mechanism advances the spits through the housing in sequential fashion and drives the spits in rotation within the housing, and is operative to ensure that each spit resides within the housing for a pre-determined length of time to ensure that the poultry is properly cooked, thereby avoiding undercooking and overcooking.
Patent AU-5275186-A (AU)
Title: Improved process for preparing sucrose encrusted methylcellulose particles for use in bulk laxative compositions
Inventor: SHAH DHIREN N
IPC: A61K9/50
Filed: 1986-01-28
Abstract: The present invention relates to an improved process for preparing sucrose encrusted methylcellulose particles which readily disperse in cold aqueous liquids. These encrusted particles are suitable for use in bulk laxative compositions. In the improved process, hot sucrose syrup is mixed with powdered methylcellulose, dried and milled.
Patent AU-5321990-A (AU)
Title: Needling process for spunbonded composites
Inventor: SERAFINI FRANCO LUIGI
IPC: D04H3/10
Filed: 1990-04-12
Abstract: A process is disclosed for manufacturing a high strength composite structure by needling individual webs of initially spunbonded material and then needle-punching a stack of the individual webs to enmesh and entangle filaments across the webs, with little or no loss of the initial filament-related strength.
Patent AU-5575896-A (AU)
Title: Structure-based designed herbicide resistant products
Inventor: KAKEFUDA GENICHI
IPC: G16B15/20
Filed: 1996-04-19
Abstract: Disclosed herein are structure-based modelling methods for the preparation of acetohydroxy acid synthase (AHAS) variants, including those that exhibit selectively increased resistance to herbicides such as imidazoline herbicides and AHAS inhibiting herbicides. The invention encompasses isolated DNAs encoding such variants, vectors that include the DNAs, and methods for producing the variant polypeptides and herbicide resistant plants containing specific AHAS gene mutations. Methods for weed control in crops are also provided.
Patent AU-5656399-A (AU)
Title: Dairy product and method for preparing same
Inventor: VERMIN REINIER JOHANNES CHRIST
IPC: A23C9/12
Filed: 1999-09-14
Abstract: The invention relates to a method for preparing a dairy product, in which a medium comprising milk or a milk product is treated under aerobic conditions with a lactose-negative, food-technologically acceptable microorganism, and is then kept under anaerobic conditions for some time. Furthermore, the invention relates to a dairy product obtainable by this method.