baber/WOPTO huggingface dataset:
Patent AU-638064-B2 (AU)
Title: Glycosyl-etoposide prodrugs, a process for the preparation thereof and the use thereof incombination with functionalized tumor-specific enzyme conjugates
IPC: A61K47/48
Filed: 1990-10-19
Granted: 1993-06-17
Abstract: The present invention relates to glycosyl-etoposide prodrugs, process for their preparation and their use in combination with functionalised tumour-specific enzyme conjugates for the treatment of cancers, and it specifically relates to 4'-O-glycosyl-etoposides as prodrugs which can be cleaved to cytotoxic agents on exposure to tumour-specific enzyme conjugates, where the liberated agent is suitable, by reason of its cytostatic activity, for the treatment of cancers.
Patent AU-742176-B2 (AU)
Title: Suppression of malignancy utilizing ribonucleotide reductase R1
Inventor: WRIGHT JIM A
IPC: C12N5/09
Filed: 1998-03-18
Granted: 2001-12-20
Abstract: The present invention provides a method of modulating the malignant properties of a cell in a human or other mammal by contacting a neoplastic cell with a growth modulating amount of an expressible nucleic acid sequence for ribonucleotide reductase R1 of the mammal. The present invention also provides and uses a growth modulating amount of the ribonucleotide reductase R1 protein or biologically active peptide to modulate the malignant properties of a cell in a human or other mammal. The method provides for a generally elevated expression of the R1 component of mammalian ribonucleotide reductase. The expressible nucleic acid sequence can be in the form of a vector for gene therapy.
Patent AU-678239-B2 (AU)
Title: Elevator machinery
Inventor: AULANKO ESKO
IPC: B66B11/04
Filed: 1994-06-24
Granted: 1997-05-22
Abstract: The elevator machinery (26) comprises a motor (6) and its traction sheave (18). The rotor (17) is disc-shaped and air gap (ir) between it and the stator (14) forms a plane which is substantially perpendicular to the shaft (13). The stator (14) forms a ringlike sector (28) and is placed in an outer part and the traction sheave (18) is fixed to the rotor, between the stator (14) and the shaft (13). The diameter of the traction sheave is smaller than that of the rotor. The structure of the motor allows the use of traction sheaves (18) of different diameters (2*Rv) with rotors (17) of the same diameter. The motor is very flat, i.e. its length in the axial direction is small. <IMAGE>
Patent AU-725841-B2 (AU)
Title: P53 protein variants and therapeutical uses thereof
Inventor: CONSEILLER EMMANUEL
IPC: C07K14/82
Filed: 1996-07-17
Granted: 2000-10-19
Abstract: Proteins derived from the product of tumor suppressor gene p53 and having enhanced functions for therapeutical use are disclosed. The proteins advantageously have enhanced tumour suppressor and programmed cell death inducer functions, particularly in proliferative disease contexts where wild-type p53 protein is inactivated. Nucleic acids coding for such molecules, vectors containing same, and therapeutical use thereof, particularly in gene therapy, are also disclosed.
Patent AU-630778-B2 (AU)
Title: Float aerator
Inventor: NORDENSKJOLD REINHART VON DR
IPC: B01F13/00
Filed: 1991-01-07
Granted: 1992-11-05
Abstract: The invention relates to a floating aerator for introducing air into a stretch of water, in particular an activated sludge plant, having at least one air supply line extending over the water surface and at least one base aerator which is suspended below the water surface by means of a float mounted on the air supply line and at least one connecting line branching off from the air supply line and which introduces air into the stretch of water at that point. To simplify mounting and to improve the operation of such floating aerators, the invention proposes that the air supply line is constructed as a continuous hose line (3) and that the float comprises at least two shaped parts (6, 7) which form a float and which are mounted on the hose line and enclose the hose line (3) completely or partly in a through opening formed by the shaped parts. 
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Patent AU-680663-B2 (AU)
Title: Use of terpene compounds for reduced release of arachidonic acid and of inflammation mediators
Inventor: JUERGENS UWE R
IPC: A61K31/405
Filed: 1994-06-11
Granted: 1997-08-07
Abstract: PCT No. PCT/EP94/01900 Sec. 371 Date Feb. 23, 1995 Sec. 102(e) Date Feb. 23, 1995 PCT Filed Jun. 11, 1994 PCT Pub. No. WO94/28895 PCT Pub. Date Dec. 22, 1994Disclosed is a method of treatment of steroid requiring inflammatory diseases using certain saturated monocyclic and bicyclic terpene compounds. These compounds may be administered in the form of capsules resistant to gastric juice, infusion solutions or intramuscular injection solutions. Because these particular terpene compounds exhibit steroid-like effects but without the harmful side-effects of conventional corticosteroids, the use of corticosteroids is substantially reduced, and in some cases, completely eliminated. Therefore, these terpene compounds are also suitable for long-term therapy and prophylaxis.
Patent AU-741791-B2 (AU)
Title: Crosslinked biological products, process for obtaining such products, and their use as removers
Inventor: BONHOURE JEAN-PAUL
IPC: C08B31/00
Filed: 1998-04-01
Granted: 2001-12-06
Abstract: PCT No. PCT/FR98/00658 Sec. 371 Date Nov. 19, 1998 Sec. 102(e) Date Nov. 19, 1998 PCT Filed Apr. 1, 1998 PCT Pub. No. WO98/44004 PCT Pub. Date Oct. 8, 1998The invention relates to the field of biological chemistry, and to polysaccharides in particular. Specifically, it concerns biological products obtained as a result of the polymerization and crosslinking in an alkaline medium of a gel, comprised of wheat or spelt wheat flour, in the presence of a dual-function crosslinking reagent. The invention further relates to a process for obtaining said biological products, consisting in forming an aqueous dispersion of flour, rendering this dispersion alkaline by adding an alkaline metal hydroxide, performing polymerization and crosslinking in the presence of a dual-function crosslinking reagent, and drying the resultant gel to obtain a vitreous, lightly colored product with a solid substance content of between 75% and 85% which is then ground into hard particles of a predetermined size. The application of the invention is abrasive particles.
Patent AU-672515-B2 (AU)
Title: Filler block
Inventor: BASSE HARTWIG
IPC: C02F3/10
Filed: 1994-06-20
Granted: 1996-10-03
Abstract: Filler block (10) for making trickling filters or immersion trickling filters, as used for the biological treatment of waste water. The pipe sections (11) of which the filler block (10) is composed have a network-like jacket (12) in which the pipe sections (11) are bonded on the jacket side by jointing points (13) to prevent narrowings in the free cross-section of the pipe sections (11).
Patent AU-768520-B2 (AU)
Title: Triazolopurine derivatives, drug compositions containing the same and adenosine A3 receptor affinitive agents
Inventor: OKAMURA TAKASHI
IPC: A61P9/06
Filed: 2000-09-22
Granted: 2003-12-18
Abstract: Disclosed is triazolopurine derivatives represented by the general formula (I): <CHEM> wherein R<1> and R<2> are as defined in the description. This compounds exhibit affinity for adenosine A3 receptor and are therefore useful as the ingredient of pharmaceutical compositions.
Patent AU-730134-B2 (AU)
Title: Latent heat body
Inventor: FIEBACK KLAUS
IPC: A47G23/04
Filed: 1998-04-03
Granted: 2001-02-22
Abstract: The invention relates to a latent heat body comprising a paraffin-based storage material accommodated in a carrier material provided with recesses, wherein the carrier material is composed of individual elements, wherein capillary-type recesses are provided for the latent heat storage material between the elements of said carrier material. According to the invention, the latent heat body can contain a plurality of defined latent heat bodies which can be surrounded by a common sheath and the latent heat body contains a microwave-active substance. The invention also relates to a corresponding production method for said bodies.
Patent AU-608228-B2 (AU)
Title: Compositions for preventing graft rejection
Inventor: COHEN IRUN R
IPC: A61P37/00
Filed: 1987-06-25
Granted: 1991-03-28
Abstract: The invention relates to means for preventing or for delaying the rejection of allografts in humans and for the alleviation of and for treating autoimmune diseases in humans. The pharmaceutical compositions which are suitable to attain the above ends ard based on heparin, on N-desulfated, on N-acetylated heparin or other suitable derivatives of heparin. The dosage which is effective is one which is substantially lower than that required for obtaining an anticoagulant effect in mammals. It is generally of the order of about 1 per cent to about 10 per cent of the anti-coagulant effective dosage of such compounds.
Patent AU-679109-B2 (AU)
Title: Matrix metalloprotease inhibitors
Inventor: CASTELHANO ARLINDO L
IPC: C07F9/6561
Filed: 1994-07-27
Granted: 1997-06-19
Abstract: Compounds of formula (I), wherein the dashed lines denote optional double bonds; and when n is 1, 2 or 3; m is 3 or 4; A is -CH2-; R<1> is a) -CH2-R<4> where R<4> is mercapto, acetylthio, carboxy, hydroxyaminocarbonyl, N-hydroxyformamidomethyl, alkoxycarbonyl, aryloxycarbonyl, aralcoxycarbonyl, benzyloxyaminocarbonyl, or (i), where R<6> is optionally substituted aryl, wherein the aryl group is quinol-2-yl, naphth-1-yl, naphth-2-yl, pyridyl or phenyl; b) -CH(R<7>)-R<8> where R<7> is alkyl, hydroxy, amino, aminomethyl, alkylsulphonylamidomethyl, aralkylsulphonylamidomethyl, alkoxycarbonyl, alkoxycarbonylaminomethyl, alkylaminocarbonylamidomethyl, benzoxazoleaminomethyl, aminocarbonyl, or carboxy; and R<8> is carboxy, hydroxyaminocarbonyl, alkoxycarbonyl or aralkoxycarbonyl; c) -NH-CH(R<9>) -R<10> where R<9> is hydrogen, alkyl or aralkyl, and R<10> is carboxy, alkoxycarbonyl, aralkoxycarbonyl, phosphonyl or dialkylphosphonyl; R<2> is alkyl, cycloalkyl, cycloalkylalkyl or aralkyl; and R<3> is hydrogen, halo, alkyl or alkoxy; or when n is 2 or 3; m is 3 or 4; A is -N(R<11>)-, where R<11> is hydrogen or alkyl; and R<1>, R<2> and R<3> are as defined above; or when n is 0; m is 4, 5 or 6; A is -CH(R<12>)-, where R<12> is carboxy, alkoxycarbonyl or optionally substituted carbamoyl; and R<1>, R<2> and R<3> are as defined above; as single stereoisomers or mixtures thereof; or pharmaceutically acceptable salts thereof; are useful in inhibiting matrix metalloprotease activity in mammals.
Patent AU-574615-B2 (AU)
Title: Vacuum refining
Inventor: SCHWENNINGER RONALD LEE
IPC: C03B5/225
Filed: 1987-08-11
Granted: 1988-07-07
Abstract: In the process for refining glass or the like by vacuum, the collapse of foam is expedited by heating the headspace within the vacuum chamber.
Patent AU-593484-B2 (AU)
Title: Servo system for magnetic recording using optical gratings
Inventor: FORD VERNON E
IPC: G11B5/58
Filed: 1987-08-17
Granted: 1990-02-08
Abstract: Magnetic recording media, and magnetic recording systems using such media, are disclosed which incorporate a light-transmitting optical grating at least substantially coextensive with the magnetic recording area. A second light-transmitting optical grating is associated with the magnetic transducer or read/write head. A moire pattern is produced by light transmitted through both optical gratings, and changes in the moire pattern resulting from changes in the alignment of the optical gratings resulting from movement of the read/write head relative to the media are utilized to provide servo information to keep the magnetic transducer aligned with the magnetic track. Higher magnetic recording capacities may be obtained using such media and systems, since none of the magnetic recording area is used for servo information.
Patent AU-678067-B2 (AU)
Title: An installation for the reprofiling of tracks carried out on a railway line
Inventor: JAEGGI JEAN-PIERRE
IPC: E01B31/13
Filed: 1994-12-02
Granted: 1997-05-15
Abstract: The surface re-shaper consists of two milling units equipped with height control cylinders (4,5,6,) and each comprising a frame (8,9), rollers (18) and a milling tool (24,24'), mounted beneath a railway vehicle (2). The two frames are articulated relative to one another about a pivot (20) with its axis perpendicular to the lengthwise axis of the rail, and they are of different lengths. The milling tools are mounted on supports (22,22') which can slide vertically relative to the frames, and connected to jacks (23) which control their positions relative to the rail. The re-shaper also has a rail heater situated in front of the milling tools, and a cooler behind them. A collector with a suction channel or magnet gathers the material removed from the rail surface during re-shaping.
Patent AU-689512-B2 (AU)
Title: Process for the preparation of polyloefins
Inventor: KUBER FRANK DR
IPC: C08F10/00
Filed: 1994-12-21
Granted: 1998-04-02
Abstract: The present invention relates to a process for the preparation of a polyolefin by polymerisation of at least one olefin in the presence of a stereorigid metallocene compound containing, as ligands, at least two substituted or unsubstituted cyclopentadienyl groups bonded to one another via a monocyclic or polycyclic ring system, where at least one cyclopentadienyl group is fused to the monocyclic or polycyclic ring system.
Patent BG-52203-B2 (BG)
Title: Method for the preparation of 2-brom-alpha -ergocryptine-methanesulphonate
Inventor: JANACHKOVA MILKA I
IPC: C07D519/02
Filed: 1987-04-02
Abstract: The method can be used in human medicine for the treatment ofendocrine disorders and for the treatment of Parkinson's disease.It makes use of accessible reagents. The 2-brom--ergocryptine-methanosulphonate is produced by the reactionbetween ergocryptine and trialkylsylylation agent such ashexamethyldisalasan or trimethylchlorsylan in ratio 1 to at least3 molequivalents. The reaction occurs in inert solvent attemperature range from 0oC to boiling of the mixture. Afterreaction with 1 to 2 molequivalents the bromiding agent such asN-bromsuccinimide or N-bromcaprolactam at temepratures from -60 to50oC. The bromine derivative is washed in aqueous solution of softreducers, sodium carbonate and water. After the evaporation of thesolvent the sylyl protection is removed. The produced base isfiltered across floricyl and is purified after which it reactswith equimolar quantity of methanesulphonic acid in acetone mediumat -5 to 20oC. The bromization and sylylation is made in inertmedium.4 claims
Patent BG-52136-B2 (BG)
Title: Method for the simultaneous treatment of an acquired form of dysplasia of the permanent teeth in combination with teeth and jaw deformations in children
Inventor: APOSTOLOVA VENETA B
IPC: A61C7/00
Filed: 1989-05-23
Abstract: The method is applied in children dentistry. It restores the anatomical integrity of the permanent first molar teeth with dysplasia and corrests the ratio of dental arcs until the attainment of organatic closing grip. After making an imprint the working occlusion is determined after which the anatomical form of the first permanent molar teeth is functionally restored by cast inserts or crowns. Parallel to this an orthodontic apparatus is made thus achieving multiple contact between the teeth of the upper and lower jaw.
Patent DE-2008261-B2 (DE)
Title: Locking device for shut-off valve - has bolt to prevent unauthorised opening or closing of valve by screwing onto operating spindle
IPC: F16K35/06
Filed: 1970-02-23
Abstract: The shut-off valve is opened or closed by rotating handwheel which has an internal thread which engages the valve spindle. A cylindrical block is screwed on to the end of the spindle and locked by a screw. A bolt normally projects outside the block and comes into contact with the edge of the cylindrical housing and so prevents the valve being closed. The bolt is provided with a slot which engages a pin projecting from the plug which is locked by the pin. When the pin is removed a special key is used to rotate the plug which withdraws the bolt, allowing the valve to be closed.
Patent DE-2113234-B2 (DE)
Title: Centrifugal crusher with high throughput - has rotating grille with eccentrically located rotor operating in same sense
IPC: B02C17/00
Filed: 1971-03-18
Abstract: The aim of the design is to propose a centrifugal crusher with increased throughput. The crusher consists of housing (1) provided with inlet opening (2) on one of the side walls for the material feed. Inside the housing a grille (3) is rotating with subcritical speed. The grille consists of sets of rings assembled to create gaps between the individual rings which are held together by tie rods (5) and distancing blocks. Inside the ring a rotor (9) is provided with impact elements is rotating in the same direction as the grille. The rotor is positioned eccentrically in relation to the centre of the grill. The grille rotates on supporting rollers (7) which at the same time act as friction drive for the grille. The inner edges of the rings (3) are fitted with a number of bars (8) which in accordance with the sense of rotation of the grille lift up and drop the material onto the rotor.
Patent DE-2144688-B2 (DE)
Title: Vee belt transmission tensioning device - has hydraulic piston, slow speed piston and springs acting on jockey pulley with speed dependent pressure
IPC: F16H7/12
Filed: 1971-09-07
Abstract: A tensioner for a V-belt transmission prevents undesirable vibrations of the jockey pulley and furnishes the desired tension under any working conditions without overstressing the V-belt at any time. Below a certain speed, only a spring (9) acts through a slow speed piston (8) on the hydraulic piston (7) and through the cranked lever (5) on the jockey pulley. At rising speed, hydraulic fluid from the port (20) compresses the spring (9) and retracts the piston (8). The movement to the right of the piston (7) by the spring (26) frees the bore (22); hydraulic fluid now acts on the piston (7) and tensions the V-belt. A still higher pressure will throttle the port (22) until an equilibrium is established.
Patent DE-2146613-B2 (DE)
Title: Electrolyte concn. measurement - using expansion of an ion exchange membrane whose movement is detected by electrodes
IPC: H01M10/48
Filed: 1971-09-17
Abstract: Process for determining the concn. of an electrolyte soln. uses the osmotic expansion of an ion exchange membrane, used either on its own or attached to a neutral carrier. An a.c. electric field is developed in the electrolyte by means of two fixed contacts and the posn. of the membrane is determined by a third contact which moves between the other two. The membrane is firmly anchored at one end and tensioned by means of spring. A probe is attached to the end of the membrane and measures the field strength. The membrane can be in the form of a strip with the probe mounted on the end. It can take the form of a pair of two material arcs joined at each end. The field electrodes are mounted either side and the probe is mounted in the middle of one.
Patent DE-2204964-B2 (DE)
Title: Piano bottom plate with laminated resonant board - has spaced ribs fitted in middle section with spaced shoulders and flat fluting between
IPC: G10C3/06
Filed: 1972-02-03
Abstract: The resonant board front side carrier strips, while its near side is fitted with elongated, mutually spaced, ribs. The centrally placed ribs have weakened points, each consisting of a pair of shoulders. The latter are distanced in the rib long direction and extend across the direction of these ribs. Between the rib ends and the shoulders is provided an elongated fluting. Preferably this arrangement of weakened points is carried out on three central ribs. The fluting may be rather flat. The resonant board may be rectangular, the ribs forming a sharp angle with one board edge.
Patent DE-2212898-B2 (DE)
Title: Large site concrete bridge platform above heavy traffic - with alternating narrow slab structures and hollow box structures
IPC: E04B1/20
Filed: 1972-03-17
Abstract: Large-area bridge platform, made of site concrete, as required above railway tracks in a station, or other traffic routes, has a flat soffit for accommodation of building and traffic loads, and for service ducts, and comprises a number of stable multicellular hollow box structures combined with columns, separated by lengthways joint gaps. The platform overall cross-section is made up from a system of narrow slab structures (I,II) and the hollow box structures (III,IV), arranged alternately. The slab structures are also linked to the columns to produce stable, statically independent part structures. Two narrow slab structures of this type can be erected first, before the intervening box structures are made, to serve temporarily as travelling bridges for a wide-span gantry crane which assists in the erection of the latter.
Patent DE-2218919-B2 (DE)
Title: Information display with carrying case unfolded to form stand - has lid removed and hinged to base opposite way round
IPC: B42F13/40
Filed: 1972-04-19
Abstract: The carrying case, has the top and bottom (10, 11) of the case hinged together at two sides via a hinge pin (131), formed integrally with an extension wing (13) of one of the two, which fits into a corresponding opening (141) in an extension wing (14) of the other. The lid (11) fits within the projecting side edge (101) of the bottom (10) of the case and is formed at the opposite sides to the former hinges (131, 141) with further hinge parts (15) allowing the lid (11) to be fully removed and then hinged to the bottom (10) the opposite way round. Pref. the lid has additional hinge pins, each of which can fit into a guide slot in the projecting side edge (101) of the bottom of the case.
Patent DE-2236347-B2 (DE)
Title: Modular sockets for electrical equipment - have tongue and groove construction with positive location end stop
IPC: H01R13/514
Filed: 1972-07-25
Abstract: Identical socket mouldings interlink by means of a groove down one side, and a moulded ridge extending down the other. The slot and matched ridge extending down only part of the side length. At the front end of th groove is a stop which prevents the neighbouring moulding sliding beyond its correct position. Beyond this, a flat vertical flange is provided with a single fixing screw by which means either individual, or groups of, sockets can be attached to a panel. The sockets are thus fixed by one or two holding elements without any special frame or additional fastening plates.
Patent DE-2237854-B2 (DE)
Title: Line protection relay with polygonal characteristic - has shunt reactance to resistance ratio altered by onset of fault
IPC: H02H3/38
Filed: 1972-08-01
Abstract: A distance measuring circuit (1) is connected to an impedance shunt (Z's) whose resistance/reactance ratio corresponds to that of the system being protected. In series with the shunt is a resistor (R1) in parallel with a second resistor (R2) and a choke (L1). These individual components form a second impedance shunt (Zs) connected to a directional circuit (2). The partial shunt (Z's) assists in detecting a fault quickly, whereupon a realy (2) responds to insert the additional resistor (R2) by opening a switch (S) after the transients have decayed. The directional circuit (2) can then complete the protection operation.
Patent IE-S59994-B2 (IE)
Title: A greeting card
Inventor: DAWSON MICHAEL PHILIP
IPC: B42D15/02
Filed: 1994-01-25
Abstract: PCT No. PCT/IE94/00023 Sec. 371 Date Jul. 25, 1996 Sec. 102(e) Date Jul. 25, 1996 PCT Filed May 3, 1994 PCT Pub. No. WO95/19893 PCT Pub. Date Jul. 27, 1995A greeting or other card plays an appropriate aural message and serves as a presentation vehicle for a gift or other article such as a lottery ticket. The card includes a device for playing a tune or verbal message and has mounting slots for the article. When seated in the slots, the article interrupts the electrical circuit of the device, preventing playback of the tune or message. On removal of the article, a switch of the device closes to complete an electrical circuit which causes the aural greeting to sound.