baber/WOPTO huggingface dataset:
Patent CA-2999769-A1 (CA)
Title: Therapeutic compounds and methods of use thereof
Inventor: BERGERON PHILLIPE
IPC: A61P29/00
Filed: 2016-09-27
Abstract: The invention provides a compound of formula: or a salt thereof, wherein the variables RAA, n, ring A, ring B, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, and R9 have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.
Patent CA-2999973-A1 (CA)
Title: Administration d'agents actifs a l'aide d'une bande de nanofibres
Inventor: DILUCCIO ROBERT
IPC: A61K31/54
Filed: 2016-08-31
Abstract: Il est décrit un système et une méthode d'administration de taurolidine. Le système d'administration de taurolidine comprend une bande, ainsi qu'une taurolidine de nanofibres transportée par la bande de nanofibres. Le système d'administration de taurolidine est formé par mélange de taurolidine et de poly(lactide-co-glycolide) 14/86 ayant un poids moléculaire de 66 à 107 kilodaltons pour former une solution, puis par électrofilature de la solution pour former une fibre biodégradable ayant une taurolidine incorporée dans le corps de la fibre biodégradable.
Patent CA-3001993-A1 (CA)
Inventor: GLINER VADIM
IPC: G06T7/30
Filed: 2018-04-18
Abstract: A method includes, identifying, in a three-dimensional (3D) anatomical image of a patient organ, multiple anatomical points corresponding to respective predefined locations on a skin of the patient organ in a first coordinate system. Multiple positions in a second coordinate system, measured by a position sensor of a position-tracking system at the respective predefined locations on the skin of the patient organ, are received. At each predefined location, a distance is calculated between a respective anatomical point and closest bone tissue of the patient organ. Weights are assigned to the predefined locations based on respective distances between the anatomical points and the closest bone tissue. The first and second coordinate systems are registered, by correlating between the positions and the respective anatomical points using the assigned weights.
Patent CA-3003460-A1 (CA)
Inventor: LEE CATHERINE
IPC: A61F13/00
Filed: 2016-10-07
Abstract: A pramipexole transdermal patch for treatment of neurological disorders including Parkinson's disease that may be administered on a daily basis. The pramipexole transdermal patch of the present invention preferably comprises a drug-containing layer that comprises pramipexole or a pharmaceutically acceptable salt thereof at 2% to about 15% by weight of the dru- containing layer and at least two acrylic polymers wherein each polymer may further comprise carboxyl and/or hydroxyl functional groups. The pramipexole transdermal patch of the present invention may further comprise two or more permeation enhancers with combined pramipexole solubility of great than 50mg/mL.
Patent CA-3004628-A1 (CA)
Inventor: STUDER CHRISTIAN
IPC: G05B19/418
Filed: 2016-12-01
Abstract: A system (46) for monitoring and/or registering a position of a tool (10) in an elevator shaft (30) comprises a position measuring system (48) for measuring a position of the tool (10) relative to an elevator car (34); an elevation measuring system (50) for measuring an elevation of the elevator car (34) in the elevator shaft (30); and an evaluation system (52) designed to receive measured data from the position measuring system (48) and the elevation measuring system (50) and determine a position of the tool (10) relative to the elevator shaft (30) from the measured data.
Patent CA-3007895-A1 (CA)
Inventor: PHILIPPE NICOLAS
IPC: G16B50/00
Filed: 2016-12-16
Abstract: L'invention porte sur une architecture (100) pour l'analyse de données génomiques comportant notamment : - une pluralité de nuds applicatifs (101), chacun des nuds applicatifs comportant : o un système de calcul (102) comportant au moins un nud de calcul, le système de calcul (102) étant construit et agencé pour réaliser des calculs de génomique, o une interface homme-machine (103) construite et agencée pour communiquer avec le système de calcul (102), o une interface d'accès (104) à une base de connaissances, - une base de connaissances (105) construite et agencée pour communiquer avec la pluralité de nuds applicatifs (101), ladite base de connaissances (105) contenant des données génomiques.
Patent CA-3009690-A1 (CA)
Title: Structures composites incorporant des composantes fabriquees de maniere additive
Inventor: RILEY P GRAVES H
IPC: B33Y40/00
Filed: 2018-06-26
Abstract: Une méthode de fabrication dun composite comprend lapplication dune première couche composite à une surface doutillage dun outil positionnant un composant de fabrication additive sur au moins une partie de la première couche composite et lapplication dune deuxième couche composite sur au moins une partie de la couche composite et au moins une partie du composant de fabrication additive, qui est encastré entre la première et la deuxième couche composite.
Patent CA-3014549-A1 (CA)
Inventor: SCHOUENBORG JENS
IPC: A61N1/372
Filed: 2017-02-23
Abstract: In a method for implantation of a physically stabilized aggregate of living cells or tissue fragment is injected into a channel provided in soft tissue filled with an aqueous gel. Also discloses are methods of stabilizing such aggregates and fragments and of forming such channel in soft tissue as well as means for carrying out the methods.
Patent CA-3014838-A1 (CA)
Inventor: Cheng Hsin-Lin
IPC: F16H37/00
Filed: 2018-08-21
Abstract: A stepless transmission capable of operating continuously having a supportive rotating element; a plurality of transmission spheres disposed on the supportive rotating element; a plurality of driving rods rotatably connected to the transmission spheres; a power input clamping rotating element; a power output clamping rotating element, wherein the transmission spheres are disposed between the power input clamping rotating element, power output clamping rotating element and supportive rotating element; an accelerating planet gear train; a first decelerating planet gear train; a transmission shaft; a first one-way transmission rotating element connected between the transmission shaft and a carrier of the planet gear train; a second one-way transmission rotating element connected between the carrier of the planet gear train and a first carrier of the first decelerating planet gear train. Therefore, the stepless transmission capable of operating continuously to transmit power instantly and steadily.
Patent CA-3017775-A1 (CA)
Title: Controlling heating elements in a wind turbine system
Inventor: BADGER PAUL
IPC: F03D80/40
Filed: 2017-03-30
Abstract: Examples are generally directed to techniques for controlling a temperature of a blade in a wind turbine system. One example of the present disclosure is a method of controlling a temperature of a blade in a wind turbine system. The method includes setting a target temperature, inputting physical conditions of the blade and ambient conditions about the blade into a processor, outputting a minimum amount of energy to a heating element of the blade required to reach the target temperature based on the physical conditions and ambient conditions, and adjusting the energy provided to the heating element to reach the target temperature.
Patent CA-3019657-A1 (CA)
Inventor: HOCKE HEIKO
IPC: C08G18/79
Filed: 2017-05-03
Abstract: The invention relates to a method for producing a polyisocyanurate composite material, comprising the following steps: a) providing a polyisocyanate composition A) which contains monomer polyisocyanates at an amount of at least 2 wt. %, and b) catalytically trimerising the polyisocyanate composition A) in the presence of at least one fibrous filler material B) and a trimerisation catalyst C), to form the polyisocyanurate composite material, said trimerisation catalyst C) comprising at least one quaternary ammonium salt and/or a metal salt. The invention also relates to polyisocyanurate composite materials that can be obtained according to the claimed method, and to the use of same to produce a component and components consisting of or containing a claimed polyisocyanurate composite material.
Patent CA-3019990-A1 (CA)
Inventor: GOFF MALCOLM
IPC: E21B17/10
Filed: 2018-10-05
Abstract: A rod guide is provided for use on a rod string extending through a bore of a wellbore tubular. The rod guide has an elongate, generally cylindrical body configured to be connected in-line with a rod string, and a plurality of wheels rotatably fastened to the outside of the cylindrical body and configured to roll along the wellbore tubular. The plurality of wheels are angularly offset from each other to provide multiple rolling planes upon which the rod guide my roll, and can be arranged in series or in opposing pairs. The wheels also assist in centralizing the rod guide in the wellbore tubular. When arranged in a helical pattern, the wheels also facilitate rotation of the rod string.
Patent CA-3021573-A1 (CA)
Inventor: MASSON STEPHEN C
IPC: A61N1/36
Filed: 2016-04-13
Abstract: L'invention concerne un système de neuromodulation comprenant des électrodes de neuromodulation sur un support d'électrode qui peut être positionné à l'intérieur d'un vaisseau sanguin pour la stimulation transvasculaire de nerfs cibles. L'aire surfacique de la cathode, l'écartement cathode-anode et d'autres paramètres sont sélectionnés pour la capture de types spécifiques de nerfs (nerfs sympathiques, parasympathiques et/ou mixtes), de nerfs situés à des distances plus éloignées ou plus courtes par rapport à la paroi vasculaire, et également pour la capture d'un nerf approprié pour des types ciblés de nerfs.
Patent CA-3023956-A1 (CA)
Inventor: Hu fu-ming
IPC: A61B5/00
Filed: 2017-05-11
Abstract: A method is provided for predicting that a caregiver will order a blood transfusion during a treatment. The method includes obtaining, on a processor, first data that indicates values for one or more parameters of a characteristic of a peak of a Fourier transform of a continuous photoplethysmographic (PPG) waveform or a continuous electrocardiogram (ECG) waveform or both collected during the treatment. The method further includes applying, on the processor, coefficients to the values for the one or more parameters. The method further includes determining, on the processor, second data that indicates a prediction that the caregiver will order the blood transfusion during the treatment based on applying the coefficients to the values. The method further includes presenting on a display device output data based on the second data. An apparatus is also provided for predicting that the caregiver will order the blood transfusion during the treatment.
Patent CA-3024927-A1 (CA)
Inventor: READMAN MATT
IPC: F16J15/56
Filed: 2016-11-24
Abstract: A vent is provided between a sealing surface and a gap. An aperture to the vent on the sealing surface is relatively small so that fluid pressure does not act to deform the seal as it crosses said aperture. Said aperture is spaced off-set from the gap on the sealing surface. The off-set provides a portion of sealing surface adjacent the gap and between the gap and aperture against which the seal can contact. The vent acts to allow fluid to enter the gap before the seal starts to cross the gap and to therefore act to equalise pressure on either side of the seal. Consequently, as the seal transitions across the gap and the sealing between two parts is lost, the fluid pressure imbalance that would otherwise act to deform the seal into the gap has been reduced. The risk of seal damage during the transition has been reduced.
Patent CA-3025486-A1 (CA)
Title: Sondes oligonucleotidiques et utilisations de celles-ci
Inventor: DOMENYUK VALERIY
IPC: C40B20/04
Filed: 2017-05-25
Abstract: L'invention concerne des procédés et compositions pour identifier des oligonucléotides qui se lient à des cibles d'intérêt. Lesdites cibles comprennent des tissus, des cellules, des biomarqueurs circulants tels que des microvésicules, y compris ceux résultant de diverses maladies. Lesdits oligonucléotides peuvent être utilisés dans des applications diagnostiques et de thérapeutiques.
Patent CA-3026888-A1 (CA)
Title: Dispositif pour la diffusion de substances volatiles
Inventor: CABALLERO TAPIA MOISES
IPC: A61L9/12
Filed: 2017-06-07
Abstract: L'invention concerne un dispositif comprenant un réceptacle (1) qui définit un col (2), un liquide qui imprègne des moyens de diffusion (3, 4) étant logé à l'intérieur du réceptacle (1), caractérisé en ce que lesdits moyens de diffusion comprennent une bande souple (3) et une bande rigide (4) en contact l'une avec l'autre, la bande souple (3) étant en contact avec le liquide à l'intérieur du réceptacle ; le dispositif comprend également un élément de fermeture interne (5) qui s'adapte étroitement à l'intérieur dudit col (2) et un élément de régulation (6) complémentaire dudit élément de fermeture interne (5), la bande rigide (4) étant associée audit élément de régulation (6), dont la position détermine la surface de la bande rigide (4) disposée à l'extérieur du réceptacle (1). Il permet de réguler avec précision la surface exposée de la bande rigide, ce qui permet de réguler l'intensité du parfum dans une pièce.
Patent CA-3027044-A1 (CA)
Inventor: BENATUIL LORENZO
IPC: A61K31/337
Filed: 2017-06-07
Abstract: The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
Patent CA-3027175-A1 (CA)
Title: Cannula assembly for robotically assisted pressure regulated laparoscopic surgical procedures
Inventor: AUGELLI MICHAEL J
IPC: A61B34/30
Filed: 2017-07-11
Abstract: A cannula assembly for use in robotic surgery is disclosed that includes a robotic cannula having a housing with an open end and a tubular portion extending distally from the housing, the tubular portion being dimensioned to accommodate passage of a surgical instrument having a 12 mm diameter, an adapter assembly configured for engagement within the open end of the cannula housing and including a tubular body with a passage supporting a primary seal dimensioned to accommodate passage of a surgical instrument having a 12 mm diameter, and an insert tube dimensioned to extend through the passage of the body portion of the adapter assembly and the tubular portion of the robotic cannula, the insert tube including a head portion with a passage supporting a secondary seal dimensioned to accommodate a surgical instrument having an 8 mm diameter.
Patent CA-3027630-A1 (CA)
Title: International trade finance blockchain system
Inventor: DOWLING MICHAEL
IPC: G06Q40/00
Filed: 2017-06-30
Abstract: A method includes generating a blockchain-based letter of credit ("BLC") relating to a contract for a trade transaction between a seller and a buyer. The BLC defines documentary and supply chain flow payment trigger events. The BLC is stored and accessible via a blockchain. A plurality of documentary flow events related to the BLC are tracked and recorded on the blockchain, and are linked to the BLC. A plurality of supply chain flow events related to a physical status of a good involved in the trade transaction are tracked and recorded on the blockchain. Each of the plurality of supply chain flow events are linked to the BLC. Payment for the contract for the trade transaction is transferred to the seller in response to detecting occurrence of both of the documentary and supply chain flow events corresponding to the respective documentary and supply chain flow payment trigger events.
Patent CA-3028423-A1 (CA)
Title: Nitric oxide donors
Inventor: RIESINGER STEVEN
IPC: C07C29/08
Filed: 2017-06-21
Abstract: The present invention provides, in part a novel class of nonoate compounds which exhibit nitric oxide releasing activity and their pharmaceutically acceptable salts, esters and prodrugs. The compounds release nitric oxide upon activation by contact with plasma. The present invention also relates to the use of the disclosed compounds to deliver nitric oxide to treat disorders arising from nitric oxide dysregulation.
Patent CA-3029549-A1 (CA)
Inventor: COZMA CLAUDIA
IPC: A61K49/00
Filed: 2017-07-03
Abstract: The present invention is related to the in vitro use of lyso-Gbl as a draggable target in the development of a drug, and to antagonist of lyso-Gbl for use in the treatment and/or prevention of a disease, wherein the disease is Gaucher disease or Parkinson's disease
Patent CA-3034199-A1 (CA)
Inventor: GROSS GWEN MARIE LANPHERE
IPC: B01D39/20
Filed: 2017-08-24
Abstract: Carbon fiber composite additives, media incorporating the carbon fiber composites, and related methods are provided herein. In some aspects, a composition includes at least one medium; and a carbon fiber composite incorporated with the at least one medium, the carbon fiber composite including one or more carbon fibers with an epoxy resin matrix applied thereto to produce a composition having improved characteristics and filtration performance.
Patent CA-3038457-A1 (CA)
Title: Gate valve
Inventor: COWIE GAVIN DAVID
IPC: E21B29/04
Filed: 2017-11-07
Abstract: A gate valve apparatus comprises a housing defining a flow path, a first valve seat located within the housing around a periphery of the flow path and comprising a first peripheral seal surface, and a gate valve member which is moveable laterally across the flow path between a first position in which the flow path is open and a second position in which the flow path is closed. A first cutter is provided on an edge region of a first surface of the gate valve member to be moveable across the flow path with the gate valve member along a first cutting plane. A first seal pocket is defined by a depression in the first surface of the gate valve, wherein a second peripheral seal surface is provided within the first seal pocket. The first valve seat and the gate valve member are axially moveable relative to each other to permit a portion of the first valve seat to become received into the first seal pocket of the gate valve member when said gate valve member is located within its second position to provide sealing engagement between the first and second peripheral seal surfaces.
Patent CA-3039074-A1 (CA)
Inventor: KUMAR RAVINDRA
IPC: A61K38/18
Filed: 2017-10-04
Abstract: In some aspects, the disclosure relates to activin and/or GDF antagonists and methods of using activin and/or GDF antagonists to treat, prevent, or reduce the progression rate and/or severity of kidney disease, particularly treating, preventing or reducing the progression rate and/or severity of one or more kidney disease-associated complications.
Patent CA-3041343-A1 (CA)
Inventor: MANGETTE STEPHEN T
IPC: B66F9/075
Filed: 2017-11-10
Abstract: A method for adjusting the position of a steered wheel of a vehicle includes detecting a steering position value of a steering control device of a vehicle such that the steering position value corresponds to an angular position of the steering control device; calculating a traction speed breakpoint at or above which steering desensitization may occur; and defining a maximum commencement steer angle at or below which steering desensitization may commence. The method also includes determining if the angular position of the steering control device or an angular position of the steered wheel is equal to or less than the maximum commencement steer angle; detecting a traction speed of one of a traction motor or a traction wheel of the vehicle; determining if the traction speed is equal to or above the traction speed breakpoint; and calculating, by the processor, a steering desensitization value when the angular position of one of the steering control device or the steered wheel is equal to or less than the maximum commencement steer angle and the traction speed is equal to or above the traction speed breakpoint.
Patent CA-3042506-A1 (CA)
Inventor: TANNA NIKUNJ NARENDRA
IPC: G01N33/68
Filed: 2017-11-01
Abstract: La présente invention concerne des protéines de liaison pour la filamine A (FLNA). En particulier, l'invention concerne des anticorps dirigés contre FLNA. Un anticorps selon l'invention peut être un anticorps pleine longueur ou une partie de cet anticorps se liant à un antigène. L'invention concerne également des procédés de préparaion et des procédés d'utilisation des anticorps de l'invention dans des méthodes de diagnostic, de surveillance et de pronostic du cancer de la prostate.
Patent CA-3049399-A1 (CA)
Title: Image based train length determination
Inventor: OSWALD JAMES A
IPC: B61L25/02
Filed: 2019-07-10
Abstract: In a method of determining a length of a train, a first camera at the head of the train acquires a first image of a first object on or proximate a path of the train and a second camera at the end of the train acquires a second image of a second object on or proximate the path of the train. A controller determines a length of the train based on a first geographical location associated with the first object in the first image and a second geographical location associated with second object in the second image. The first and second geographical locations of the first and second objects can be determined from corresponding prerecorded images of the objects that are geotagged with the geographical locations of the objects.
Patent CA-3052070-A1 (CA)
Title: Anti-cxcr4 antibodies
Inventor: MCALLISTER ANDRES
IPC: C07K16/00
Filed: 2017-01-31
Abstract: The present invention relates to monospecific antibodies against CXCR4 or binding fragments thereof, to the use of such anti-CXCR4 antibodies or binding fragments in treating diseases whose pathogenesis is related to activation of CXCR4, as well as to pharmaceutical compositions comprising such anti-CXCR4 antibodies or binding fragments.
Patent CA-3053905-A1 (CA)
Title: Intermitter valve
Inventor: MCCASKILL LANE PATRICK
IPC: F16K31/00
Filed: 2018-02-15
Abstract: An intermitter valve for controlling the flow rate and/or pressure of a fluid produced from a well drilled into an oil and gas reservoir includes several seals between a seat connected to the valve body and a sleeve connected to a reciprocating stem. An O-ring disposed in an inner groove of the sleeve can be used to intermittently form an elastomer-to-metal seal against the seat. An O-ring disposed in an outer groove of the seat can be used to intermittently form an elastomer-to-metal seal against the sleeve. A surface proximate to the end of the sleeve can be used to intermittently form a metal-to-metal seal against a surface of the seat. The seat and the sleeve can be part of a valve kit for converting a production choke valve into a flow shut-off device.
Patent CA-3054890-A1 (CA)
Title: Appareil d'enregistrement du son, systeme sonore, procede d'enregistrement du son et moyen de support
Inventor: MATSUURA ATSUSHI
IPC: H04S7/00
Filed: 2018-03-14
Abstract: L'invention concerne un appareil, un système et un procédé, dont chacun permet : d'acquérir des données sonores générées à partir d'une pluralité de signaux sonores recueillis au niveau d'une pluralité de microphones ; d'acquérir, à partir d'un ou de plusieurs capteurs, le résultat de la détection de la position de l'appareil d'enregistrement du son à un instant donné pendant une période de temps lorsque la pluralité de signaux sonores est recueillie ; et de stocker, dans une mémoire, des données de position indiquant la position de l'appareil d'enregistrement du son détectée à l'instant donné, et des données sonores générées sur la base d'une pluralité de signaux sonores recueillis au niveau des microphones au moment où la position a été détectée, en association les unes avec les autres.
Patent CA-3056017-A1 (CA)
Inventor: KULANGARA CAROLINE
IPC: C07K14/005
Filed: 2018-03-22
Abstract: The present invention relates to self-assembling protein nanoparticles with built-in six-helix bundle proteins. Proteins or peptides comprising a loop region are stabilized by attaching them to six-helix bundle (SHB) proteins and integrating them into self-assembling protein nanoparticles (SAPNs).