baber/WOPTO huggingface dataset:
Patent AU-4998799-A (AU)
Title: Topical compositions comprising an opioid analgesic and an nmda antagonist
Inventor: KOLESNIKOV YURI
IPC: A61K31/706
Filed: 1999-07-15
Abstract: A topical opioid paradigm was developed to determine analgesic peripheral effects of morphine. Topical morphine as well as peptides such as [D-Ala2,MePhe4,Gly(ol)5]enkephalin (DAMGO) produced a potent, dose-dependent analgesia using the radiant heat tailflick assay. The topical drugs potentiated systemic agents, similar to the previously established synergy between peripheral and central sites of action. Local tolerance was rapidly produced by repeated daily topical exposure to morphine. Topical morphine tolerance was effectively blocked by the N-Methyl-D-Aspartate (NMDA) receptors antagonist MK801 and ketamine given either systemically or topically. NMDA receptor antagonists reversed pre-existing morphine tolerance. The activity of topical NMDA antagonists to block local morphine tolerance suggests that peripheral NMDA receptors mediate topical morphine tolerance. Morphine was cross tolerant to [D-Ala2,MePhe4,Gly(ol)5]enkephalin (DAMGO), but not to morphine-6β-glucuronide, implying different mechanisms of action. These observations have great importance in the design and use of opioids clinically. Topical pharmaceutical compositions comprising an analgesic that functions through an opiate receptor and an NMDA receptor antagonist for producing analgesia without inducing tolerance are described.
Patent AU-5014196-A (AU)
Title: Monoclonal antibody reacting specifically with fas ligand and process for producing the same
Inventor: KAYAGAKI NOBUHIKO
IPC: C07K16/28
Filed: 1996-03-21
Abstract: A monoclonal antibody reacting specifically with Fas ligands or the active fragment thereof; a process for producing a monoclonal antibody reacting specifically with Fas ligands; hybridomas producing a monoclonal antibody which reacts specifically with Fas ligands existing on the cell surface or soluble ligands; a method for detecting Fas ligands in a solution; and a kit for detecting Fas ligands which comprises a combination of monoclonal antibodies for Fas ligands.
Patent AU-5296896-A (AU)
Title: Method and device for obtaining a free disperse system in liquid
Inventor: KOZYUK OLEG VYACHESLAVOVICH
IPC: B01F3/08
Filed: 1996-02-20
Abstract: A method of obtaining a free disperse system in liquid which produces a controlled hydrodynamic cavitation by regulation of constriction ratio, volumetric flow rate, and degree of cavitation parameters. Selection of the parameters with regard to the properties of components of the fluid make it possible to effectively treat the components having a variety of physio-chemical characteristics. The invention further relates to the construction of a cavitation device wherein the geometry of a flow-constricting baffle body effectively increases the degree of cavitation to substantially improve the quality of an obtained free disperse system.
Patent AU-5395999-A (AU)
Title: Use of estrogenic and anti-estrogenic compounds as anti-fungal compounds
Inventor: GREEN SHAWN J
IPC: A61K31/56
Filed: 1999-08-10
Abstract: The present invention provides compounds that are useful for inhibiting the proliferation of fungi. The compounds are estrogenic derivatives, such as 2ME2, or anti-estrogenic compounds. The compounds may be used for treating infections of fungi in humans and animals, or to prevent or inhibit the growth of fungi on any surface.
Patent AU-5413400-A (AU)
Title: Process for making morphine-6-glucuronide and its analogues using haloglucuronate ester intermediates
Inventor: SCHEINMANN FEODOR
IPC: C07H13/04
Filed: 2000-06-20
Abstract: A process for manufacturing morphine-6-glucuronide and related compounds of the general structure of Formula 1:wherein optionally substituted morphine is conjugated with an optionally substituted member of a new class of intermediates, namely, 1-haloglucuronate esters, in the presence of iodine or an iodinium compound. The conjugation may be followed by conversion of R<1 >of Formula 1 into hydrogen and/or the removal of the ester groups from the glucuronic residue at R<2 >of Formula 1.
Patent AU-5421599-A (AU)
Title: Providing a service in a communication system
Inventor: DELLAVERSON LOU
IPC: H04W4/24
Filed: 1999-08-09
Abstract: A method of providing an information service in a communication system includes giving the user a plurality of options related to values of at least one communications parameter to be used during the provision of service, for selection therefrom by the user. Possible communications parameters are bandwidth, delay, error rate and communications route. The invention is particularly advantageous in network arrangements including cellular radio communication systems, such as UMTS.
Patent AU-5433496-A (AU)
Title: Synthetic peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus
Inventor: MOZES EDNA
IPC: A61K38/00
Filed: 1996-03-27
Abstract: Synthetic peptides based on a complementarity-determining region (CDR) of the heavy or light chain of a pathogenic anti-DNA monoclonal antibody that induces a systemic lupus erythematosus (SLE)-like disease in mice, and analogs, and salts and chemical derivatives thereof; dual peptides comprising two such peptides or analogs covalently linked to one another either directly or through a short linking chain; peptide polymers comprising a plurality of sequences of said peptide or analog thereof; and peptide polymers attached to a macromolecular carrier, are disclosed, and pharmaceutical compositions comprising them for the treatment of SLE in humans.
Patent AU-5479090-A (AU)
Title: Ceramic material and method for producing the same
Inventor: MACMILLAN SHAUN T
IPC: C04B28/26
Filed: 1990-05-04
Abstract: A method of providing a ceramic coating on a substrate, for example of aluminum, where a slurry of a zirconium compound such as zirconia and a silicate such as potassium silicate is coated on a substrate and cured at a temperature not exceeding 500<o>F.
Patent AU-5500486-A (AU)
Title: Process to preserve acid-producing bacteria
Inventor: BARACH JEFFREY T
IPC: C12R1/46
Filed: 1986-03-21
Abstract: Described is a method to stabilize or preserve acid-producing bacteria in a buffered solution. A carrier may be added that is not a specific substrate for the bacteria in order to give texture, most preferably the carrier being polyethylene glycol or sodium alginate. Optionally, other ingredients such as anti-oxidants, mold inhibitors, and/or salts may be added. These compositions may be stored at temperatures above freezing for a time from a few days up to about 2 months or longer.
Patent AU-5746500-A (AU)
Title: An anti-microbial silicone rubber composition and method making said composition
Inventor: HANKE BERNHARD
IPC: A01N59/16
Filed: 2000-06-16
Abstract: An anti-microbial body care cosmetic composition comprising in the part contacting the human or animal skin and/or mucosa and organic matrix containing homogeneously dispersed particles of a metallic silver having a particle size in the range of 1 to 50 nm (silver nanoparticles) in an amount providing on the surface of said part and anti-microbially effective but less than cytotoxic silver concentration.
Patent AU-5823090-A (AU)
Title: Composite plastic pipe
Inventor: DIERICKX PATRIECK
IPC: B29C70/08
Filed: 1990-06-29
Abstract: Composite plastic pipe, characterized in that it principally consists in the combination of an extruded pipe in thermoplastic synthetic material and a pultruded pipe or pipe obtained by pull winding in thermoplastic or preferably thermo-hardening synthetic material which fit closely.
Patent AU-5997090-A (AU)
Title: Arylpyrazole derivatives as anti-platelet agents
IPC: C07D403/06
Filed: 1990-07-30
Abstract: Compounds of the formula <CHEM>  wherein R<1> and R<2> each are independently hydrogen or phenyl, provided that R<1> and R<2> may not both be hydrogen;  m is an integer from 3 to 9;  n is an integer from 0 to 3 and the sum of  m+n is an integer from 5 to 12;  Z is O, S, SO, SO2, -CH=CH- or a direct bond;  A is <CHEM>  R<3> is hydrogen or C1-6 alkyl; and  R<4> is hydrogen, C1-4 alkyl or methylsulfonyl; and pharmaceutically acceptable salts or hydrates thereof are novel inhibitors of adenosine diphosphate and collagen-induced aggregation of human platelet-rich plasma and are particularly useful as inhibitors of mammalian blood platelet aggregation.
Patent AU-6148286-A (AU)
Title: Hydrocarbyl-substituted succinic acid/anhydride/amine terminated poly (oxyalkylene)
Inventor: FORSBERG JOHN W
IPC: C10N40/22
Filed: 1986-07-25
Abstract: A composition is disclosed which comprises a water-dispersible reaction product of (A) at least one compound represented by the formula  <IMAGE>  wherein R is a hydrocarbyl group of from about 8 to about 40 carbon atoms, with (B) at least one water-dispersible amine terminated poly(oxyalkylene). Aqueous concentrates and water-based functional fluids comprising these compositions are also disclosed. These reaction products are useful as shear-stable thickeners for such functional fluids.
Patent AU-6231390-A (AU)
Title: Isoxazoles herbicides
Inventor: ROBERTS DAVID ALAN
IPC: C07C49/794
Filed: 1990-09-07
Abstract: Compounds of formula <CHEM>  wherein R<1> represents: an optionally substituted alkyl, alkenyl, or alkynyl group ; or an optionally substituted cycloalkyl group; or an optionally substituted cycloalkenyl group ; or a group such as aryl, aralkyl, COOR<3>, COR<3>, CN, NO<2>, NR<3>R<4>, OR<5>, halogen atom. R2 represents a group such as NO<2>, CN, R<5>, S(O)mR<5>, SO2NR<3>R<4>, COOR<3>, COR<3>, CONR<3>R<4>, CSNR<3>R<4>, OR<5>, or alkyl substituted by OR<5>, or a halogen atom.  R<3> and R<4> represent H or an optionally substituted alkyl.  R<5> represents an optionally substituted alkyl  m represents zero, 1 or 2  n represents an integer from 1 to 5  p represents zero or 1 and agriculturally acceptable salts thereof. The herbicidal composition comprising these compounds and their application to crop protection.
Patent AU-6269786-A (AU)
Title: Steerable catheter with doppler means
Inventor: MILLAR HUNTLY D
IPC: A61B8/12
Filed: 1986-09-15
Abstract: A steerable catheter having a Doppler crystal at the tip to measure the velocity of blood in vivo-and inferentially the blood flow. The catheter includes two passageways, one passageway being exposed to the blood stream with the other passageway containing the electrical leads to the Doppler crystal. The one passageway is dimensioned for receiving a wire guide for accurately manipulating the catheter. Preferably, the catheter incorporates an inflatable angio-balloon operable to distend the blood vessel in the region of a stenosis. Thus, blood flow can be determined in the region of the stenosis before and/or after the vessel is distended. The passageways are preferably defined by a pair of generally concentric tubes with the Doppler crystal doughnut-shaped and sealingly disposed at the tip of the catheter.
Patent AU-6286680-A (AU)
Title: Production of acetic anydride
Inventor: KUBBELER HANS-KLAUS
IPC: C07C51/54
Filed: 1980-10-01
Abstract: The invention relates to an improved process for making acetic anhydride by reacting methyl acetate and/or dimethylether with carbon monoxide under practically anhydrous conditions, at temperatures of 350 to 575 K., under pressures of 1 to 300 bars, and in the presence of a catalyst system containing noble metals belonging to group VIII of the periodic system of the elements, or compounds thereof, iodine and/or its compounds, and an aliphatic carboxylic acid having 1 to 8 carbon atoms. The improved process is effected in the presence of a catalyst system containing, as additional ingredients, a heterocyclic aromatic compound, in which at least one hetero atom is a quaternary nitrogen atom, or a quaternary organophosphorus compound, and a zirconium compound being soluble in the reaction mixture.
Patent AU-6292890-A (AU)
Title: Food grade laked pigment dispersion composition
Inventor: SIGNORINO CHARLES A
IPC: A61K8/98
Filed: 1990-08-06
Abstract: Improved stable, fluid, aqueous dispersion compositions comprise a pigment, an alkali metal, alkaline earth metal or ammonium salt of a linear aliphatic substituted glycine such as a salt of ethylene diamine tetraacetic acid or nitrilo triacetic acid as a stabilizing agent, and water. The dispersion composition may additionally contain a lower alkanol such as methanol and/or a water soluble plasticizer such as propylene glycol. Coating compositions for use as a film coating for tablets and the like contain the above-described stable, fluid, aqueous dispersion composition, a water soluble plasticizer, a film coating resin, and water. The described fluid, aqueous dispersion compositions have been found to remain stable for extended periods exceeding six months.
Patent AU-6568400-A (AU)
Title: Rotary threshing and separation unit
Inventor: VISAGIE ANDRIE
IPC: B07B1/20
Filed: 2000-07-31
Abstract: A rotary threshing and separation unit, comprising a rotor housing (12) with a feeding zone, a separation zone and a discharge zone, parts of the circumferential housing being closed and other parts having openings, a threshing and separation rotor (16) arranged in said rotor housing, beater plates fixed on said threshing and separation rotor, main sucking air flow stream generating means (18) sucking a main air flow stream through the rotor housing, and auxiliary air flow stream generating means (18) sucking an auxiliary air flow stream through a space underneath the sieve means and baffle plates arranged in the space underneath the sieves, is disclosed. To improve the separating function of the baffle plates, it is suggested to releasably fix at least one baffle plate to the threshing and separation unit. Also disclosed is a grain loss sensor (44) fixed on a baffle plate (36) and an electronic control device (46) that adjusts the setting of at least one baffle plate.
Patent AU-6568794-A (AU)
Title: Multifunction hand-held device
Inventor: APPELHOFF HUBERT
IPC: B25F1/00
Filed: 1994-04-14
Abstract: PCT No. PCT/EP94/01150 Sec. 371 Date Oct. 20, 1995 Sec. 102(e) Date Oct. 20, 1995 PCT Filed Apr. 14, 1994 PCT Pub. No. WO94/23907 PCT Pub. Date Oct. 27, 1994A multifunctional hand-held device has a plate-like body around the circumference of which are shaped various tools which project from the body. Other tools having different functions are formed by recesses or indentations arranged around the circumference and formed in the plate-like body. An embodiment of the hand-held device looks approximately like a frog with a head, a neck and two legs. The device is made of metal.
Patent AU-6584994-A (AU)
Title: Low-molecular dna from sturgeon milt, a method of obtaining the dna and a pharmaceutical preparation based on it
Inventor: ASAFOV ALEXANDR VILENOVICH
IPC: A61P37/04
Filed: 1994-04-14
Abstract: The present invention relates to low-molecular DNA extracted from sturgeon milt and to a pharmaceutical preparation on its base. The invention also discloses a method for preparation of low-molecular DNA from sturgeon milt. A description is given of a new preparation based on low-molecular DNA for use in the capacity of a hemocorrector, inhibitor of viral activity, particularly HIV infection, and for treating lesions of the mucous membrane of different etiologies. Also disclosed is the use of low-molecular DNA as a universal cosmetic addition.
Patent AU-6703500-A (AU)
Title: Closing system, especially for motor vehicles
Inventor: KLEIN HELMUT
IPC: E05B81/64
Filed: 2000-08-26
Abstract: A closing system for doors having a container provided in a handle. The container has a touch surface that is placed in a window-type recess of the handle, and a switching element that is arranged in the container can be actuated by the touch surface. The switching element is used to switch the control electronics of the closing system between two states, namely a state that prevents opening of the door and a state that allows the door to be opened.
Patent AU-6758100-A (AU)
Title: Hyperpolarized gas transport devices and associated transport methods using permanent magnets
Inventor: HASSON KENTON C
IPC: F17C1/00
Filed: 2000-08-02
Abstract: A transport unit includes a plurality of permanent magnets arranged to provide a magnetic holding field for protecting hyperpolarized gas during storage and/or transport. The permanent magnets are configured in a relatively light weight manner to project a substantially cylindrical magnetic holding field or spherical holding field in space. The magnet arrangements can include primary magnets and field shaping secondary magnets which act to enlarge the region of homogeneity. The permanent magnet arrangement can also be provided with a cylindrical shaped flex sheet magnetically activated to provide the magnetic holding field. The permanent magnet arrangements do not require disassembly to insert or remove one or more containers of hyperpolarized gas in or out of the transport unit.
Patent AU-6876700-A (AU)
Title: Prostaglandin derivatives
Inventor: SATO FUMIE
IPC: A61P43/00
Filed: 2000-09-08
Abstract: A prostaglandin derivative represented by the formula: <CHEM> wherein X is a halogen atom in the  alpha - or  beta -position, Y is an ethylene group, a vinylene group or an ethynylene group, A is a group represented by the formula: O(CH2)n, S(O)p(CH2)n, O(CH2)qO(CH2)r, O(CH2)qS(O)p(CH2)r, S(O)p(CH2)qS(O)p(CH2)r or S(O)p(CH2)qO(CH2)r (wherein n is an integer of 1 to 5, p is 0, 1 or 2, q is an integer of 1 to 3, and r is 0 or 1), R<1> is a C3-10 cycloalkyl group, a C1-4 alkyl-C3-10 cycloalkyl group, a C3-10 cycloalkyl-C1-4 alkyl group, a C5-10 alkyl group, a C5-10 alkenyl group, a C5-10 alkynyl group or a bridged cyclic hydrocarbon group, R<2> is a hydrogen atom, a C1-10 alkyl group or a C3-10 cycloalkyl group, and m is 0, 1 or 2Ü, a pharmaceutically acceptable salt thereof or a hydrate thereof. The present invention is to provide novel PG derivatives having an excellent PGD2-like agonistic activity and a sleep-inducing action.
Patent AU-6922294-A (AU)
Title: Improved rail tie, tie plate and clip
Inventor: IGWEMEZIE JUDE ODIHACHUKWUNMA
IPC: E01B3/16
Filed: 1994-06-02
Abstract: A rail tie plate (410, 420, 440, 460, 478) comprises two elements each provided with a rail flange shoulder (414), a downward leg (421) and a lateral projection (422) whereby the tie plate can be installed on a plate member (21, 121, 221, 321) of a slotted steel tie (20, 120, 220, 320) by insertion of the projection (422) of each element into a respective slot and rotation of the element inwardly and downward. A tie plate (410, 420, 440, 450, 460, 478) having longitudinal shoulders (414) is provided with a downwardly facing abutment surface such as provided by an opening (424) laterally through each shoulder (414) on which a rail clip (430, 470, 482, 489) engages to bear on an upper side of the rail flange (416). Rail rollover is avoided by transferring rotational forces to the plate (410, 420, 440, 450, 460, 478) through the engagement of the clip (430, 470, 482, 489) on the shoulder (414) and resisting such rotational force at the connection between the tie plate (410, 420, 440, 450, 460, 478) and the tie (20, 120, 220, 320). A steel tie for incorporation in a rail track has a horizontal oblong rectangular plate member (21, 121, 221, 321) for connection transversely of the rail, and a web (23) or webs (123, 223, 323) extending vertically on the underside of the plate member (21, 121, 221, 321) and spaced inwardly from its longer sides. A ballast engaging plate member (33, 41, 133, 233, 333) may be connected on the tie on its underside and faces generally transversely of the rail or ends of the plate (21, 121, 221, 321) may be bent downwardly.
Patent AU-6930281-A (AU)
Title: Aqueous polyisocyanate lignin adhesive
Inventor: LAMBUTH A L
IPC: C08L75/04
Filed: 1981-04-08
Abstract: An aqueous polyisocyanate-lignin adhesive for use particularly in the manufacture of wood composition board comprises in admixture with each other an organic polyisocyanate and the lignin product resulting from the chemical pulping of lignocellulose.
Patent AU-6988391-A (AU)
Title: Method and apparatus for necking containers
IPC: B65D1/40
Filed: 1991-01-22
Abstract: A die necking method and apparatus for producing a smooth tapered wall between the container side wall and a reduced diameter neck includes a plurality of rotatable necking turrets that each have a plurality of identical necking substations each having a necking die. The necking dies in the respective turrets have an internal configuration to produce a necked-in portion on the container which has a first arcuate segment integral with the container side wall and a second arcuate segment integral with the reduced diameter neck. The necking substations also have a floating form control element that engages the inner surface of the container to control the portion of the container to be necked. The necked-in portion is reformed in each succeeding turret by dies to produce a smooth tapered wall between the arcuate segments.
Patent AU-7114687-A (AU)
Title: Arificial, absorbable ligament prosthesis
Inventor: BENICEWICZ BRIAN C
IPC: A61F2/08
Filed: 1987-04-07
Abstract: An absorbable ligament and tendon prosthesis is disclosed. The prosthesis is made from a polymer of L(-)lactide and may contain up to 10% glycolide as a comonomer. The polymerization mass includes an organo metallic catalyst present in a monomer to catalyst mole ratio of from 10,000 to 50,000 and a monofunctional alcohol, as an end cap, in a monomer to alcohol mole ratio of from 600 to 1400 to 1. The filaments of the prosthesis have diameters of from 3 to 15 microns and the total diameter of the prosthesis is between 20 and 80 mils.
Patent AU-7406281-A (AU)
Title: N-substituted aniline derivatives
Inventor: HAMPRECHT G
IPC: A01N43/82
Filed: 1981-08-13
Abstract: N-Disubstituted aniline derivatives of the formula    <IMAGE>  I where R is C1-C4-alkyl, C1-C4-alkoxy, C2-C4-alkoxyalkyl or halogen, R1 is C1-C4-alkyl or halogen, R2 is hydrogen, C1-C4-alkyl or halogen, R3 is CH[OR5]2, COOR5 or COSR5, R5 being C1-C4-alkyl, and R4 is unsubstituted or methyl-, nitro- or halogen-substituted 1,2,3-thiadiazol-4-yl or 1,2,3-thiadiazol-5-yl, and the manufacture thereof. The novel compounds have microbicidal properties.
Patent AU-7428298-A (AU)
Title: Catheter for measuring chemical parameters, in particular for introducing into biological tissues, liquids or the like
Inventor: HAINDL HANS
IPC: A61B5/00
Filed: 1998-04-02
Abstract: A catheter used to measure chemical parameters, in particular to be inserted into biological tissue, fluids or the like, comprising a feed duct running longitudinally through the catheter to its outer end for the purpose of feeding a liquid, further a return duct running through the catheter to return the liquid and a partly permeable tubular membrane at the end of the catheter and enclosing the flow path between the end of the feed duct and the return duct. This catheter is characterized in that the feed duct (26) substantially coaxially encloses the return duct (4), or vice-versa, in that the tubular membrane (16) forms at least in the vicinity of the catheter end an inner wall (10) of the radially external return duct or the radially external feed duct (26), that the feed duct (26) and the return duct (4) communicate with each other at the catheter end by at least one radial aperture (24) and in that spacers are provided which brace the inner wall (10) of the radially external tubular part (12) and/or of the tubular membrane (16) against the external wall (6) of the inner tubular part (2).The catheter can be manufactured in simple and economical manner and makes possible a small diameter and small dead space and allows measurement without substantial time-delay at a high measurement level.