baber/WOPTO huggingface dataset:
Patent EC-SP11011204-A (EC)
Title: Compuestos de quinazolina sustituidos
Inventor: MIDDLEMISS DAVID
IPC: A61K31/502
Filed: 2011-07-14
Abstract: La invención se dirige a ciertos compuestos novedosos, métodos para producirlos y métodos para tratar o mejorar un trastorno mediado por cinasa. Más particularmente, esta invención se dirige un compuestos de quinazolina sustituidos útiles como inhibidores de cinasa selectivos, métodos para producir tales compuestos y métodos para tratar o mejorar un trastorno mediado por cinasa, En particular, los métodos se relacionan con el tratamiento o mejora de un trastorno mediado por cinasa que incluye enfermedades cardiovasculares, diabetes, trastornos asociados con diabetes, enfermedades inflamatorias, trastornos inmunológicos, cáncer y enfermedades de los ojos tales como retinopatías o degeneración macular u otras enfermedades vitreorretinianas, y similares.
Patent EE-200200441-A (EE)
Inventor: ALLEGRETTI MARCELLO
IPC: A61K31/12
Filed: 2001-02-06
Abstract: N-(2-aryl-propionyl)-amides of formula (I) are described. The process for their preparation and pharmaceutical preparations thereof are also described. The amides of the invention are useful in the prevention and treatment of tissue damage due to the exacerbate recruitment of polymorphonuclear neutrophils (leukocytes PMN) at the inflammatory sites. In particular, the invention relates to the R enantiomers of N-(2-aryl-propionyl)amides of formula (I) for use in the inhibition of the chemotaxis of neutrophils induced by IL-8. The compounds of the invention are used in the treatment of psoriasis, ulcerative cholitis, glomerular nephritis, acute respiratory insufficiency, idiopathic fibrosis, and rheumatoid arthritis.
Patent EG-25476-A (EG)
Title: Frac pack casing saver
Inventor: CLEM NICHOLAS J
IPC: E21B43/04
Filed: 2009-04-23
Granted: 2012-01-15
Abstract: A deflection device keeps high velocity gravel slurry flow from directly impinging the wellbore wall in open hole and breaking loose the filter cake coating on the wall or, in a cased hole, prevents the direct impingement of gravel slurry on the casing which can cause wear from erosion. The slurry exist from an intermediate annulus in a crossover that is fitted with movable members that can be pivotally mounted for rotational displacement by the pumped slurry to act as a deflector to prevent or minimize direct impingement on the wellbore wall or casing. When the flow stops the deflectors can pivot back to their original positions. The deflectors can be simply replaced when worn.
Patent GB-187303937-A (GB)
IPC: C13B10/06
Filed: 1873-12-01
Granted: 1874-04-09
Abstract: 3937. Johnson, J. H., [Meritens, A. de, and Kresser, V.]. Dec. 1. Materials, fibrous; raw materials, treating; pro- cesses. -Relates to the treatment of bagasse or sugar-cane trash in order to produce paper pulp, a certain quantity of cane juice being also obtained. The material may be heated in a closed vessel by means of injected steam or otherwise and is then passed through mill rollers &c. in order to express any juice or saccharine matter, which may then be concen- trated for conversion into sugar or alcohol. The fibrous residue is washed in a cold and slightly alkaline solution which is afterwards acidulated, the material being reduced to fibrous cellulose which may then be bleached, compressed, and dried for delivery to the paper mill. Fig. 2 shows a machine in which the bagasse is conveyed on endless bands under a spray of hydrate of lime from a reservoir F, which has a heating-pipe and is supplied from a lower tank L. The liquid is also supplied to the stuff by a channel G, H, and rollers 1 cause it to penetrate the material. The material next passes between rollers 2, which regu- late the quantity of lime left in it, and then through rollers 3, which extract the juice, and other rollers 4 &c., which separate the fibres. A trough M collects the juice, which may be used for the defecation of the whole of the juices of the works.
Patent GB-189315115-A (GB)
Title: Improvements in Pneumatic Tyres.
Inventor: CALLAGHAN WILLIAM SAMUEL
Filed: 1893-08-08
Granted: 1893-10-28
Abstract: 15,115. Macneil, J. July 9. Wood, substitutes.-Gelatinous animal tissues, such as skins, sinews, &c., are spread out and dried, at first in the air and afterwards in a room below 150‹ F. They are then powdered in a disintegrating or shredding machine, and mixed with glue or gelatine soaked in water, and some bichromate of potash, and carbolic acid ; 65 to 75 parts of the powder may be mixed with 35 to 25 parts of glue and 1 or 2 of bichromate. The mixing is effected by stirring the materials together in a heated pan, or by a mincing-machine provided with a steam jacket to heat the drum to not above 250‹ F. The bichromate may be mixed with the other materials, or these may be mixed and afterwards soaked in bichromate solution. The composition can be rolled into sheets, or moulded.
Patent GB-189706785-A (GB)
Title: Improved Chain Gearing suitable for Cycles.
Inventor: SAHLMANN JOHANES OTTO
Filed: 1897-03-15
Granted: 1897-04-17
Abstract: 6785. Sahlmann, J. O. March 15. Drawings to Specification. Chain gearing.-The surfaces of the teeth of the wheels and of the rollers on the chains are fluted or roughened to ensure the rolling of one upon the other.
Patent GB-189707791-A (GB)
Title: Improvements in Lamps.
Inventor: HOMAN WILLIAM CLIFFORD
Filed: 1897-03-25
Granted: 1897-05-29
Abstract: 7791. Homan, W. C. March 25. Lanterns.-In those lanterns in which the body of the lantern performs the functions of a chimney, the lenses and reflectors are protected from the flame by detachable shields. In Fig. 2, the front hinged reflector D, with its lens B, is protected by a shield I with a glass or transparent centre, and the back reflector G has a similar shield J.
Patent GB-189711234-A (GB)
Title: Improvements in or relating to Gigantic Wheels for Recreation or other purposes.
Inventor: THOMASON JOHN
Filed: 1897-05-05
Granted: 1898-03-19
Abstract: 11,234. Thomason, J. May 5. Roundabouts.-Relates to gigantic wheels for recreation and other purposes, in which the wheel, in addition to rotating upon its axle, is carried backwards and forwards upon rails. The wheel A, having an axle F, cars C, and swings C', is supported on each side by rollers or wheels upon rails G, while toothed pinions H on the outer side of the rollers engage with horizontal racks I running alongside the rails, and supported by the framework J. The wheel is preferably driven by two ropes or hawsers ; one B, anchored at one end at L, passing round the wheel and a pulley 0, and over rollers P to a drum M on a shaft N ; the other B<1>, anchored at L', passing round the wheel to a drum M' on the shaft N. On rotating the shaft in the direction shown by arrows, the wheel rotates, and also travels to the left, while on reversing it travels to the right. Safety appliances to prevent overwinding &c. are provided.
Patent GB-189712785-A (GB)
Title: Improved Apparatus for Photographing Objects in Motion and for Projecting the Representations upon a Screen or other surface.
Inventor: DAY CHARLES AUBREY
Filed: 1897-05-24
Granted: 1898-05-07
Abstract: 12,785. Day, C. A., [Latham, W.]. May 24. Kinematographic apparatus.- Relates to an apparatus adapted for taking and projecting pictures of moving objects. The film 25 is drawn from the reel 24 by two smooth feedrollers 14<a> and 15", passes along the focal plane of the lens 31 between layers of fur 28<b> and layers of felt 26<c>, is then drawn forward Ly another pair of feedrollers 14 and 15, and is finally wound on to the receiving-spool 24<a>. The feed-roller 14<a> is driven from the roller 14 by a pitch chain, and the roller 14 is driven by a crank handle and toothed gearing. The pressure of the roller 15 on the roller 14 can be regulated by the screw 13, which raises or lowers the frame 10 in which the roller is mouted. The pressure of the roller 15<a> is independently regulated by a screw 19 and bell crank 16. The film is drawn intermittently through the focal plane by a crank-pin 44 fixed in a slot on the rotating disc 39. The receiving-spool 24" is driven by a friction band 27 from the roller 14". The lens 31 is used for taking the photographs, but is replaced by a condenser when the pictures are projected through the lens opposite. Cylindrical shutters 33 and 38 driven by toothed gear are used in each case.
Patent GB-189714520-A (GB)
Title: Improvements In and Relating to Electric and Other Auto-Cars.
Inventor: LEIGH HENRY HARRINGTON
Filed: 1897-06-15
Granted: 1897-07-17
Abstract: 14,520. Leigh, H. H., [Soc. Charles Milde fils et Compagnie, Mandos R., and Constant, A.]. June 15. Motor r o a d vehicles.-R e l at e s to electric and other autocars. The body of the vehicle, on which the accumulators are carried, is supported, as shown in Fig. 1, on a system of steel springs H and india - rubber blocks h, and the wheels are furnished with pneumatic or other elastic rubber tyres. The motor is designed to provide for differential driving of the wheels when the vehicle is travelling i n a curvilinear path. It is constructed with two independent armatures, and the field magnet is wound so that half is in series with one of the armatures and half in series with the other armature. The armature shafts drive a pair of countershafts from which motion is communicated to the road wheels through articulated lengths of shafting. The control of the motor is effected through the medium of a pair of barrel switches, Figs. 5 and 7, which interlock, by an arrangement resembling the Geneva stop, so that a wrong action of the driver is rendered impossible. A cut-out switch is also arranged to be operated by the brake-lever whenever the brake is put on, which can be closed again only when the controlling-switch is in the ' off' position.
Patent GB-189719745-A (GB)
Title: Improved Electro-magnetic Picking Mechanism for Looms.
Inventor: FAIRWEATHER WALLACE
Filed: 1897-08-27
Granted: 1898-01-08
Abstract: 19,745. Fairweather, W., [Klein, F. E.]. Aug. 27. Magnetic looms; picking-motions.-The shuttle A contains an electromagnet, and a series of electromagnets B', B' are arranged beneath the shuttle race. Suitable contacts and circuits are arranged so that the shuttle acts as the armature of a motor and the magnets B', B<2> as field magnets, or vice versÔ. Arrangements are described for continuous and for alternating currents. If a three-phase current is employed, a short-circuited armature is placed in the shuttle and the contacts are dispensed with. In the arrangement shown in Fig. 5, the shuttle is grooved to pass over pins E, which guide it and form contacts. The dents L of the reed which are opposite the pins have enlargements, as shown in Fig. 6, to prevent the warps from catching on the pins when the shed is being formed. When dressed or twisted warps are used, it is sufficient to round off the tops of the pins. In weaving wire fabrics, the sides of the pins are covered with insulating-material. Cam-pieces H<2> at each end of the lay actuate a commutator in the shuttle to reverse the circuit through the magnet for each right or left hand throw. In weaving with a single shuttle, the magnets B may be extended as far as the position of rest of the shuttle at each end. This arrangement is, however, inapplicable in connection with a change-box mechanism, so the device shown in Fig. 1 has been designed, in which the energy of the incoming shuttle is stored in the spring s and utilized to start the shuttle again. The spring s is held in a state of compression by the trigger w, released by the withdrawal of the bar x from beneath the lever u. The shuttle is kept in contact with the buffer u on the end of the spindle t by a spring catch y, which is released as soon as the spring s has moved the shuttle through a short distance.
Patent GB-189723466-A (GB)
Title: Improvements in or applicable to the purposes of Forced Draft, Heating Air, and the like.
Inventor: FORBES CHARLES STEWART
Filed: 1897-10-12
Granted: 1898-09-24
Abstract: 23,466. Forbes, Sir C. S. Oct. 12. Air, heating.-Air for warming and ventilaling buildings and for other purposes is heated by being drawn by natural or forced draught over one or more steam condensers 1 of the kind described in Specification No. 3027, A.D. 1897.
Patent GB-189805264-A (GB)
Title: Improvements in Salt for Dietetic Purposes.
Inventor: SHEARER JAMES GARRICK
Filed: 1898-03-03
Granted: 1899-03-03
Abstract: 5264. Shearer, J. G. March 3. Salt, common.-Salt for dietetic purposes is prevented from caking by mixing it with about 2 per cent. of magnesium carbonate.
Patent GB-189814449-A (GB)
Title: Improvements in Permutation Locks.
Inventor: HAAG JOSEPH
Filed: 1898-06-30
Granted: 1899-06-24
Abstract: 14,449. Haag, J. June 30. Locks, permutation.-A slide b fits in a dovetailed groove in a block a. Three studs d, d<1>, d<11> pass through holes in the block a, and through a hole f in the slide b of the form shown in Fig. 5. They are fixed to a plate c at the back by screws i. The shanks of the studs where they pass through the slide b have flats on them as shown at e in Fig. 7, so that, when turned to a proper position, they can enter the narrow parts of the slot in the slide b, so as to allow it to be slid along in the block a. The heads of the studs d, d<1>, d<11> are marked with letters or index numbers for setting them to the correct combination, and the heads may be attached to the shanks by a screw so as to allow the combination to be changed.
Patent GB-189824842-A (GB)
Title: Improved Coin-freed Apparatus for Displaying Stereoscopic Transparencies.
Inventor: ROSE JOHN
Filed: 1898-11-24
Granted: 1899-08-12
Abstract: 24,842. Rose, J. Nov. 24. Stereoscopes.-A skeleton drum consisting of two discs A connected by four rods is turned by hand to pass before the eyes an endless chain of transparencies while an electric lamp is maintained in circuit.. A pinion C on the drum shaft drives a wheel D which bears a flange D' having a gap that breaks the circuit at a spring terminal not shown. Normally a detent G pivoted on the axle of the flanged wheel locks the drum, but a penny dropped into a pocket H at the outer end dis. engages it as shown. One side of the coin pocket being hinged, it is opened by the gapped flange acting as a cam.
Patent GB-189902435-A (GB)
Title: Improvements in Lettered Advertisements or Sign Plates or Tablets.
Inventor: EATON THOMAS
Filed: 1899-02-03
Granted: 1899-06-17
Abstract: 2435. Eaton, T. Feb. 3. Advertising; signs; letters.-To a front plate, such as of brass, through which letters &c. are cut, a back-plate of a different colour, such as of zinc, is attached. The differently-coloured metals cause the letters &c. to show up distinctly, when the fitting of wax wears away.
Patent GB-189918556-A (GB)
Title: Improvements in Apparatus for Generating Acetylene Gas.
Filed: 1899-09-14
Granted: 1900-08-04
Abstract: 18,556. British Pure Acetylene Gas Syndicate and Talbot, C. E. Sept. 14. Acetylene.-Relates to acetylene generators of the kind in which the calcium carbide is allowed to fall into an excess of water, such for example as that described in Specification No. 18,207, A.D. 1896. The water tank 1 is of the form shown, and is supplied with water at a constant level by means of a cistern 3. Supported by the cover of this tank is a charging-chamber 4, closed at the bottom by a counterweighted flap 6 and at the top by a cover 7 dipping into an annular water seal. The carbide container 10 is divided into a number of compartments, each of which is closed at the bottom by a separator door 12, the catch of which can be released by a rod 14 on turning the cover 7. When one of these compartments is emptied, the carbide drops on to the flap 6, which opens and allows it to fall on to the uppermost of a series of grids 15, 16, and 17, of graduated mesh, the falling pieces being directed outwards by a conical spreader 20. Gas leaves the apparatus by the pipe 21. When the supply is cut off, the acetylene collects in the top of the tank, and forces the water back into the cistern 3, from which it escapes by an overflow pipe.
Patent GB-189918631-A (GB)
Title: Improvements in Locks and Devices for Securing the Doors of Railway Carriages and other Vehicles.
Inventor: ALLEN GEORGE BROMLEY
Filed: 1899-09-15
Granted: 1900-06-30
Abstract: 18,631. Allen, G. B., and Clarke, H. F. P. Sept. 15. Doors, locking simultaneously.-A cord or chain B running along the train operates bolts A securing all the doors simultaneously. One end of the cord is attached to a spring S, and the other to a handlever in the guard's van. The hand-lever may be arranged to operate cords on both sides of the train, so as to lock and unlock both sets of doors simultaneously. The bolt A may be Y-shaped as shown, the cord B being attached to the arms a<5>, and the third arm serving as the catch to secure the door.
Patent GB-189923826-A (GB)
Title: Improvements in Reproducing on Paper, Fabrics, or other Materials Facsimiles of Colored Originals.
Inventor: TRUCHELUT THEODORE
Filed: 1899-11-29
Granted: 1900-11-03
Abstract: 23,826. Truchelut, T., and Rochereau, A. A. Nov. 29. Lithographic stones, preparing designs on.-Relates to the reproduction of coloured originals upon paper, fabrics, or other materials. The originals are produced in the three primary colours, yellow, red, and blue ; iodide of mercury may be employed for the red, ferrocyanide of silver for the yellow, and a mixture of aniline-blue lake, or Prussian blue, mixed with lead sulphate. These colours are finely ground together with white of egg, gum, fish glue, or other agglutinating material. The prepared original is next treated with a solution of barium chloride, or of the chloride of some other alkaline earth metal, to which a little aldehyde has been added ; in this way the yellow of the original is caused to disappear. A photograph of the original, thus treated, is then taken, and, as the blue does not reproduce, only the red parts appear in the photographic reproduction. Next, the original is treated with potassium iodide, which causes the red to disappear and the yellow to reappear, and a second photograph is taken, in which the yellow parts of the original are reproduced. The original is then treated with potassium cyanide, and developed by means of sodium sulphide or other alkaline sulphide, and a third photograph of the original is taken, showing the blue parts. From the three photographic reproductions, printing-blocks are prepared for use in printing copies of the original. According to another process, lithographic, zincographic, or similar transfers are taken from the original, in which the yellow, red, and blue colours have been respectively obtained, by mixing the pigments with fatty matter, a chromium or other suitable salt, and a mercury or other suitable salt. A transfer of the red is obtained by using a plate or stone coated with gelatine, and a stone or plate coated with albumen is used in obtaining a transfer of the blue portions of the original. In a third method, the colours contain insoluble substances, such as tannates, chromium salts, or cachou, and are applied to a surface coated with gelatine, and moistened with water and some other substances, such as a chromate, pyrogallic acid, or the like. According to a fourth process, the colours are prepared similarly to the colours used in the first-described method, and are painted upon a transparent paper, celluloid or like surface. Prints are then made, by means of the transparent original, upon stones or metal plates.
Patent GB-189925465-A (GB)
Title: Improvements in and relating to Fluid-pressure Reducing and Regulating Devices.
Inventor: ALEXANDER THOMAS WILLIAM
Filed: 1899-12-23
Granted: 1900-02-24
Abstract: 25 465. Alexander, T. W., [Alexander, J. S. L., and Schoonmaker, A. G.]. Dec. 23. Regulators.-A fluid-pressure reducing and regulating valve, specially applicable for gas pressures, is shown in Fig. 1. The inverted bell 5 is screwed on to the valve stem, and is weighted, chiefly on one side, to keep the valve 8 in contact with its seat at one side, by metal blocks 13 and 18. The block 18 may, if desired, be arranged on the top of the bell. There is a liquid sealing-pit formed by the hollow flange 4, and the low-pressure chamber is separated from it by the partition 14 and the ball bearing 16, which allows the fluid to flow through. The ball bearing may be doubled, to prevent lateral deflection of the valve stem when the deflecting-block 18 is omitted, or a rigid star-shaped bearing may be employed.
Patent GB-190004430-A (GB)
Title: Improvements in Rings for Hydraulic Hat Presses.
Filed: 1900-03-08
Granted: 1900-12-22
Abstract: 4430. Moseley, A. H., and Macintosh & Co., C. March 8. Felt hats.-The ring c<1>, Fig. 2, for a hydraulic hat press has two internal oppositely-inclined faces, and is fitted into the body a of the hat so as to obtain a sharp corner when pressed in the mould b.
Patent GB-190005220-A (GB)
Title: Improvements in Gaiters or Coverings for the Legs.
Inventor: HILL THOMAS WATSON
Filed: 1900-03-19
Granted: 1901-03-19
Abstract: 5220. Hill, T. W. March 19. Methods of fastening; Lacing-fastenings. - Gaiters &c. are fastened by threading a lace through a series of pairs of holes A formed on the underflap so as to form loops C adapted to engage hooks, studs, buttons, &c. D secured to the other flap. The lace is finally drawn tight, and is secured by passing its end through holes G formed in the underflap. The positions of the holes A and hooks D may be reversed. The gaiter may be provided with button or spring fastenings, in addition to the lace.
Patent GB-190009790-A (GB)
Title: Improvements in and connected with Safety Stop Devices for Steam and other Motive Fluid Engines.
Inventor: WRIGHT JAMES KNOX
Filed: 1900-05-28
Granted: 1900-07-28
Abstract: 9790. Wright, J. K. May 28. Stop gear; steam pipes, preventing escape of steam on bursting of.-Relates to automatic safety stop devices for steam engines, applicable to fluidpressure engines generally. The apparatus acts to stop the engine, not only when either the maximum or minimum speed allowed is reached, or when the governor strap or the safety device breaks, but also if the steam pipe bursts. As shown in the general arrangement in Fig. 1, the stop valve is operated directly by a weight 35, and is held open by a cord 27, passing to the safety device contained in a casing 1, and shown on a larger scale partly in section in Fig. 2. The cord 27 passes round a drum 26 held by a detent 40 capable of being released by a sudden rise of the rod 3<1>. This is caused to take place whenever the governor shaft 3 reaches either its highest or lowest permissible position. The rods 3 and 3<1> have respectively a casing 4 and a plunger head 5, one sliding on the other and both acted on by a spring 6. The rods are normally extended in opposition to the spring and so held by a sliding stop 9, which through the medium of a three-armed lever 11 is withdrawn, either by a rise of the governor bringing the lever against a stop 12, or by a fall bringing it against the stop 13. A device for freeing the stop 9 from the lever 11, to permit of normal stoppage of the engine, is provided. The governor rod and connections are balanced by a weight 20. Arrangements may also be provided for enabling the detent 40 to be withdrawn from a distance ; for instance, a cord 45 acting on a lever on the spindle 43, or a weight 46 releasable by an electromagnet 49 and acting on the same lever. Fig. 6 shows the substitution of a fluid-pressure connection, between the drum 26 and the valve, for the cord connection. The drum in this case operates a cock, as shown, for breaking the connection by relieving the pressure.