baber/WOPTO huggingface dataset:
Patent PT-1059481-E (PT)
Inventor: JEAN-LUC MAHE
IPC: E21B33/127
Filed: 2000-06-08
Abstract: The automatic flow-limiting safety valve comprises a rigid core with an envelope which inflates when excessive flow causes a pressure drop exceeding a specified limit The rigid core (2) is connected to retainers (4a,4b) and also supports an inflatable envelope (5). The lateral wall (503) partially delimits an internal chamber (50). It also faces the internal wall (10) of the pipe (1). The admission valve (3) is calibrated to admit fluid selectively at the upstream end of the chamber, permitting envelope inflation, when the pressure drop exceeds a given threshold. The inflatable envelope blocks the pipe selectively and at least partially, by radial displacement of its sidewall towards the internal wall of the pipe. An Independent claim is included for the method of protecting against excessive flowrate in a pipe, using the unit above. Preferred Features: The core extends along the longitudinal axis (X). The retainers are claws (41-42), each fixed at one end to the core. When folded in, claw tips are close to the longitudinal axis. In the deployed position, the free ends are remote from the axis. Each claw tends to spring outwardly (biting into the pipe). The core has a set transverse diameter (S). The length of each claw exceeds the core radius. The device has an opening (231) in the tubular core wall, and hooked fastenings (611, 621) engaging them and holding the leading and trailing ducts (614, 624) in the body. The body contains a spring-loaded ball, working between these ducts under the action of applied pressure. The claws resemble umbrella spokes, locking the core in the pipe, against movement in opposing directions.
Patent PT-1201779-E (PT)
Inventor: HERRMANN STEPHAN
IPC: H01B1/02
Filed: 2000-10-27
Abstract: Electrical conductor is made from an aluminum alloy of the AlMgSi type containing (in wt.%) 0.4-0.6 silicon, 0.15-0.2 iron, maximum 0.03 copper, maximum 0.05 manganese, 0.4-0.6 magnesium, maximum 0.01 chromium, maximum 0.03 zinc, maximum 0.02 titanium, maximum 0.03 further alloying components, and a balance of aluminum. The alloy is present in the over-aged state T7. An Independent claim is also included for a process for the production of the electrical conductor comprising extruding the above alloy to a profile and hot ageing to produce the over-aged state T7. Preferred Features: The over-aged state T7 is produced by hot ageing in the region of 160-230 degrees C for 5-30 hours.
Patent PT-1248796-E (PT)
Title: Process for the purification of antithrombin-iii
Inventor: WINGE STEFAN
IPC: C07K14/47
Filed: 2001-01-18
Abstract: A process for the preparation of a solution comprising substantially pure antithrombin-III (AT-III), or an isoform thereof, said process comprising the use of a cation exchange gel wherein the cation exchanger groups are attached to the gel matrix via a linear polymer chain.
Patent PT-1366230-E (PT)
Title: Use of pigment dyes for dispersion dyeing from aqueous media
Inventor: SIEBER HELMUT
IPC: D06P1/44
Filed: 2002-01-21
Abstract: Use of pigments according to formula (I) <chemistry id="CHEM-US-00001" num="000
Patent PT-1348628-E (PT)
Inventor: JAVIER JORBA RIBES
IPC: A61L2/24
Filed: 2003-03-21
Abstract: The method comprises viewing by means of a magnetic recording camera (13) the zone (9,9') for the opening of vials (8,8') and for metered filling thereof and continuously recording said zones visually during the operation of the installation and simultaneously carrying out the identification marking of each full glass container, with indelible marking means (11), at the outlet of the installation. <IMAGE>
Patent PT-1465890-E (PT)
Title: Stable lansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol
Inventor: LIBERMAN ANITA
IPC: A61K31/4439
Filed: 2003-11-18
Abstract: The present invention provides a stable 2-(2-pyridylmethyl) sulfinyl-1H-benzimidazole (lansoprazole) comprising either greater than 500 ppm and not more than about 3,000 ppm water or greater than 200 ppm and not more than about 5,000 ppm alcohol, or both. The present invention provides a method of preparing a stable lansoprozole as well as a pharmaceutical composition containing same. The present invention further provides a method of purifying lansoprazole that is substantially free of sulfone and sulfide derivatives.
Patent PT-1585787-E (PT)
Inventor: HUI CHIN
IPC: C08G63/48
Filed: 2003-12-19
Abstract: Polymer compositions comprising a) a polymer substrate selected from the group consisting of the polyolefins, polyesters, polyamides and polylactic acids and b) a combination of i) at least one permanent antistatic additive selected from the group consisting of the polyetheresteramides and ii) at least one migratory antistatic additive selected from the group consisting of the alkylsulfonic acid salts, the alkyl diethanolamines and the alkyl diethanolamides, are effectively antistatic.
Patent PT-1567522-E (PT)
Title: Pyrimidine compounds
Inventor: WANG SHUDONG
IPC: C07D417/04
Filed: 2003-11-14
Abstract: The present invention relates to substituted pyrimidines of formula (I), their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders and/or viral disorders.
Patent PT-1530273-E (PT)
Title: Angle accessory for duct composed of two aslant assembled flaps
Inventor: JARRY PATRICE
IPC: H02G3/06
Filed: 2004-10-14
Abstract: The attachment has two male fitting units (114, 115) and two female fitting units (124, 125) on two flaps (110, 120), respectively. A wing (116) forms an obstacle defining at least an access passage (117) of the male units. The passage has a reduced height forcing the assembly of the flaps by aligning the flap (120) with a rotation axis of the flap (110) in order to engage the female units on the respective male units.
Patent PT-1590467-E (PT)
Title: Use of regulatory sequences for specific, transient expression in neuronal determined cells
Inventor: COUILLARD-DESPRES SEBASTIEN
IPC: C12N15/63
Filed: 2004-01-28
Abstract: The present invention relates to the use of regulatory sequences for mediating specific, early transient expression in proliverative neuronal determined cells. Furthermore, the uses of recombinant nucleic acid molecules comprising said defined regulatory sequences for mediating specific, early transient expression in proliverative neuronal determined cells as well as for the generation of non-human transgenic organisms and/or host cells are disclosed. In addition, the invention provides for transgenic non-human animals and/or host cells comprising said regulatory sequences and/or recombinant nucleic acid molecules. The invention also describes methods for the preparation of such vectors, host cells and transgenic non-human animals as well as methods for the detection and/or isolation of neuronal determined cells. Additionally, methods for screening of compounds capable of regulating neuronal determined cell activity, neurogenesis, stimulating proliferation of neuronally committed precursor cells and/or neuronal differentiation are provided and the invention also relates to methods for the detection and analysis of neuronal differentiation, neuronal migration and/or neuronal determination processes. Finally, the invention relates to diagnostic and pharmaceutical compositions comprising the regulatory sequences, recombinant nucleic acid molecules, host-cells or isolated neuronal determined cells described herein.
Patent PT-1528948-E (PT)
Title: Flame arrester
Inventor: LEINEMANN CHRISTOPH
IPC: A62C4/02
Filed: 2004-06-26
Abstract: A flame arrestor for a flowing explosive gas ( 4 ), having a flame barrier ( 10, 20, 30 ) with a large number of defined passage gaps ( 17, 18 ), whose gap cross section is set with regard to the properties of the flowing gas ( 4 ), is cooled effectively and secured against a flame flashback in the case of continuous combustion by the fact that second gaps ( 18 ) having a smaller gap cross section are arranged adjacent to the first gaps ( 17 ) having the selected gap cross section.
Patent PT-1844795-E (PT)
Title: Diffuser for volatile substances with multiple fragrances
Inventor: CASERTA ANDREA
IPC: A61L9/03
Filed: 2005-02-03
Abstract: It is of the type of those which are connected to the electric mains by means of a plug (1), incorporates a single container (6) equipped with a body of two or more independent receptacles (8) which hold different liquid fragrances in which respective wicks (2) are immersed and a lid (9) which closes the body (7) and renders the receptacles; (8) independent. The lid (9) comes with openings (10) in correspondence with the positions of the wicks (2) for the egress and vaporization of the fragrance by actuation of one or more resistance elements (3), located in opposition to said openings (10), by means of a manual pushbutton (4) or automatically in accordance with a pre-established program, diffusing the fragrances in a sequential or combined manner during predetermined intervals of time.
Patent PT-1748780-E (PT)
Title: Methods and related compositions for reduction of fat
Inventor: KOLODNEY MICHAEL S
IPC: A61K31/765
Filed: 2005-05-19
Abstract: Compositions and methods useful in the reduction of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include antiinflammatory agents, analgesics, dispersion or anti-dispersion agents and pharmaceutically acceptable excipients. The pharmacologically active detergent compositions are useful for treating localized accumulations of fat including, for example, lower eyelid fat herniation, lipodystrophy grid fat deposits associated with cellulite and do not require surgical procedures such as liposuction.
Patent PT-1984235-E (PT)
Title: Apparatus and method for reducing fluid drag on a submerged surface
Inventor: STUBBLEFIELD DONALD P
IPC: B63B1/38
Filed: 2006-01-27
Abstract: An apparatus and method for reducing surface friction drag on the hull of a surface vessel by entraining air into water flowing in the boundary layer flow along the hull. The apparatus creates a reduced pressure region by diverting a first portion of the flow away from the surface of the hull. An air pocket is formed in the reduced pressure region and a second portion of the flow is directed through the air pocket by nozzles, which acts as a plunging jet and entrains air into the boundary layer.
Patent PT-2029170-E (PT)
Title: Quality control methods for oil-in-water emulsions containing squalene
Inventor: KLEIN NORBERT
IPC: A61K39/39
Filed: 2007-11-06
Abstract: Measurements of the squalene content in oil-in-water emulsions can be used as a way of checking for problems during production. In particular, it has been found that a drop in squalene content can indicate that filtration problems occurred. Testing the squalene content in the final lots is easier than investigating the characteristics of the filter, and so a squalene assay simplifies the quality control of oil-in-water emulsions.
Patent PT-2121838-E (PT)
Title: Foam layer produced of a biodegradable polyester mixture
Inventor: SKUPIN GABRIEL
IPC: C08L67/02
Filed: 2008-02-11
Abstract: The invention relates to a foam ply based on a biodegradable polyester mixture, comprising i) from 70 to 5% by weight, based on the total weight of components i to ii, of at least one polyester based on aliphatic and aromatic dicarboxylic acids and on aliphatic dihydroxy compounds, and ii) from 30 to 95% by weight, based on the total weight of components i to ii, of poly-lactide, and iii) from 0.1 to 5% by weight, based on the total weight of components i to ii, of a copolymer which comprises epoxy groups and is based on styrene, acrylates, and/or methacrylates, and iv) from 0.5 to 15% by weight of additives; and v) from 0 to 50% by weight of inorganic or organic filler, and also to processes for production of the foam ply mentioned, and to the use of the foam plies for the production of moldings and foils, and also to moldings and foils comprising the foam plies mentioned.
Patent PT-2141155-E (PT)
Title: Prophylactic and/or therapeutic agent for hyperlipidemia
Inventor: TAKIZAWA TOSHIAKI
IPC: A61K31/423
Filed: 2008-03-28
Abstract: The invention provides a pharmaceutical composition for use in the prophylactic and/or therapeutic treatment of a disease selected from the group consisting of hyperlipidemia, familial hyperlipidemia, diabetes mellitus, and metabolic syndrome, the composition comprising (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl] -aminomethyl]-phenoxy]butyric acid or a salt thereof, or a solvate thereof, or a solvate of a salt thereof; and at least one statin, or a salt thereof, or a solvate thereof or a solvate of a salt thereof; with the proviso that the at least one statin is not pitavastatin.
Patent PT-2240482-E (PT)
Title: Cyclic azaindole-3-carboxamides, their preparation and their use as pharmaceuticals
Inventor: STEINHAGEN HENNING
IPC: C07D471/04
Filed: 2009-01-17
Abstract: The present invention relates to cyclic azaindole-3-carboxamides of the formula I, wherein A, R, R10, R20, R30, R40, Y1, Y2, Y3, Y4, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.
Patent PT-2264156-E (PT)
Title: Phytases
Inventor: KENSCH OLIVER
IPC: C12N1/20
Filed: 2005-10-17
Abstract: The present invention relates to enzymes and processes. In particular, there is described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme and variants thereof.
Patent PT-666252-E (PT)
Inventor: UDO ALBUS DR
IPC: C07C279/22
Filed: 1995-01-19
Abstract: Perfluoroalkyl-substd. phenylalkanoic acid guanidides of formula (I) and their salts are new: Ra, Rb = H, halogen, CN, OR6, 1-8C alkyl, 3-8C cycloalkyl, Or(CH2)aCbF2b+1 or NR7R8; r = 0 or 1; a = 0-4; b = 1-8; R6-R8 = H, 1-8C alkyl, 3-8C alkenyl, 3-8C cycloalkyl, or phenyl or benzyl opt. substd. by 1-3 of F, Cl, CF3, Me, OMe and NR9R10; R9, R10 = H, 1-4C alkyl or 1-4C perfluoroalkyl; x = 1-3; R1-R5 = H, 1-8C alkyl, 3-8C cycloalkyl, Or(CH2)aCbH2b+1, halogen or CN; provided that ≥ 1 of R1-R5, Ra and Rb = Or(CH2)aCbH2b+1.
Patent PT-877602-E (PT)
Inventor: EISTETTER KLAUS
IPC: A61K35/42
Filed: 1997-01-18
Abstract: A powdered pulmonary surfactant preparation containing a hydrophobic protein serving as a pulmonary surfactant is obtained by spray drying an organic solution or suspension containing a hydrophobic protein serving as a pulmonary surfactant and possibly other components. Obtained power preparations exhibit very good stability under storage, are easy to reconstitute and are also suitable for administration by inhalation.
Patent PT-946151-E (PT)
Inventor: HAMEL LAWRENCE G
IPC: A61K31/445
Filed: 1997-11-12
Abstract: A dosage form and a method are disclosed for delivering to a human patient a drug in an ascending amount over time.
Patent PT-975790-E (PT)
Inventor: THOMAS HASLER
IPC: A61K47/36
Filed: 1998-01-20
Abstract: The invention relates to a method for the isolation of polysaccharides, in particular for the separation of endotoxins from capsule polysaccharides of gram-negative bacteria. The polysaccharides isolated by this method are preferably used for the production of polysaccharide vaccines. The invention furthermore relates to vaccines containing polysaccharides isolated by the method described in this invention.
Patent PT-1054897-E (PT)
Title: Method for purifying prpres from a biological sample and applications
Inventor: DESLYS JEAN-PHILIPPE
IPC: G01N33/68
Filed: 1999-02-16
Abstract: The invention concerns a method for purifying PrPres from a biological sample to be used for qualitative and/or quantitative determination of the PrPres in said sample. The method essentially consists in: (1) incubating, during 30 seconds to 2 hours, at a temperature less than 80° C., said biological sample with a buffer solution A comprising at least a surfactant in an amount ranging between a quarter and four times the weight of the biological sample and optionally a protease, to form a suspension S1; (2) adding to said suspension S1 resulting from (1) a buffer solution B in an amount sufficient for thinning said suspension, which buffer solution B consists of a solvent or mixture of solvents, which does not solubilize the PrPres and has a constant dielectric ranging between 10 and 25; (3) centrifuging the suspension S2 resulting from step (2); and (4) solubilizing said pellet in a buffer solution C comprising at least a surfactant and/or at least a chaotropic agent, at a temperature ranging between room temperature and 100° C.
Patent PT-1100768-E (PT)
Inventor: GIANNESSI FABIO
IPC: C07C69/003
Filed: 1999-07-27
Abstract: R-(-)-carnitine is prepared by (a) conversion of (S)-3-hydroxy-4-butyrolactone [1] to alkyl (S)-4-halogen-3-hydroxy-butyrate [2] by reaction with a linear or branched C1-C7 alcohol (b), substitution of a CN group for the halogen of compound [2] to yield the alkyl ester of (R)-4-cyano-3-hydroxybutyric acid [3], (c) conversion of alkyl ester [3] to yield (R)-4-cyano-3-hydroxybutyramide [4], (d) cyclization of compound [4] to yield (R)-5-(cyanomethyl)-2-oxazolidone [5] via conversion of the amide function to isocyanate, (e) hydrolysis of compound [5] to yield (R)-4-amino-3-hydroxybutyric acid [6], and finally (f) methylation of the amino group of compound [6] to yield the end product (R)-carnitine.
Patent SG-73085-G (SG)
Title: Indole and indoline derivatives
IPC: C07D209/08
Filed: 1985-10-05
Abstract: Indole and indoline derivatives of the formula:  <IMAGE>  wherein indicates a double bond or a single bond between carbon atoms, R1 represents hydrogen, alkyl of 1 through 6 carbon atoms, or alkyl of 1 through 6 carbon atoms substituted by one or more than one of the same type of substituents selected from the hydroxy group, alkenyl groups of 2 through 5 carbon atoms, and alkanoyloxy groups of 2 through 7 carbon atoms, and one of the symbols R2 represents alkyl of 6 through 24 carbon atoms and the other symbol R2 represents alkyl of 1 through 24 carbon atoms or hydrogen, and R3 represents alkyl of 1 through 6 carbon atoms or hydrogen, are new compounds possessing useful pharmacological properties. They are of use in the treatment of diabetes mellitus, hyperlipoproteinaemic states, of atherosclerosis, and of associated conditions.
Patent SG-96791-G (SG)
Title: Process for preparing retinoyl chlorides
IPC: C07C401/00
Filed: 1991-11-15
Abstract: A process to prepare retinoyl chlorides, e.g., of the following formula (I): <CHEM> under very mild chlorinating conditions by the action of a reagent amount of dimethylchloroformamidinium chloride on a corresponding retinoic acid.
Patent SG-102487-G (SG)
Title: O-substituted alpha-ketocarboxylic acid oximes,processes for their preparation as well as medicaments containing these compounds
IPC: C07D295/18
Filed: 1987-11-24
Abstract: The present invention provides pyruvic acid oximes of the general formula:    <IMAGE>  (I)  wherein R is a hydrogen atom, a C3-C8 cycloalkyl, C1-C6 alkoxy, cinnamyloxy, phenylamino, phenyl-N-alkylamino or phenylthio radical or an aryl or aryloxy radical, the aryl moiety of which can be substituted one or more times by C1-C6 alkyl, C1-C6 alkoxy, halogen, hydroxyl, trifluoromethyl, amino, acetylamino, nitrile, nitro or methylenedioxy, A is a straight-chained or branched, saturated or unsaturated aliphatic hydrocarbon chain containing up to 10 carbon atoms, which can be substituted one or more times by halogen or hydroxyl, and R1 is a C1-C8 alkyl radical, which can be substituted one or more times by halogen, hydroxyl, nitrile, phenyl or carboxyl, or is a nitrile or formyl group, with the proviso that when R-A- is a methyl or ethyl radical, R1 is not a methyl radical or a nitrile group and when R-A- is a benzyl radical, R1 is not a methyl or benzyl radical; and the physiologically acceptable salts, carboxylic acid esters and amides thereof. The invention also provides processes for the preparation of these compounds pharmaceutical compositions containing them, and their use in combating hypoglycaemia.
Patent IE-880022-L (IE)
Title: Fencing tape
IPC: H01B5/00
Filed: 1988-01-06
Abstract: This invention provides a conductive tape for an electrifiable fence comprising a tape of woven or knitted construction having at least two conducting wires arranged longitudinally and integrally in the woven or knitted structure characterised by a bridging conductor carried in or on the knitted or woven structure and which is directed transversely across the two longitudinal conductors at intervals so that if a break occurs in one of the conductors the current path is capable of continuing via the bridging conductor.
Patent IE-800051-L (IE)
Title: Roller assembly
IPC: F16C29/06
Filed: 1980-01-11
Abstract: A roller assembly for supporting sliding doors on a track or rail comprises a plurality of short rollers (10) which are confined to run around an oval track (9a) formed in a two part housing (7). Some of the rollers (10) are engageable with the track through an elongate slot (13) in the base of the housing (7) so that load is distributed over several rollers. The housing (7) is mounted for adjustment in a carrier (5) which can be mounted on a door. The adjustment permits variations in height or levels to be accommodated.
[US4278306A]
Patent IE-800361-L (IE)
Title: Inhalers
IPC: A61M15/00
Filed: 1980-02-22
Abstract: An improvement in inhalation aerosol spray devices comprising a piezoelectric oscillator connected to an atomizer plate, where the improvement resides in that the working surface of the atomizer plate is coated with a thin elastomer film, whereby the particle spectrum of the aerosol generated by the device is significantly improved.
Patent IE-860677-L (IE)
Title: Antiviral formulation
IPC: C07H19/06
Filed: 1986-03-14
Abstract: 3'-azido-3'-deoxythymidine has been found to possess potent activity against human retrovirus infections particularly HTLV-I and HTLV-III infections.
[EP0291633A1]
Patent IE-41137-L (IE)
Title: 16-methyl -9ó- halo steroid esters and ethers.
IPC: A61K31/57
Filed: 1975-03-27
Abstract: 1510617 21 - Deoxy - 16 - methyl corticosteroid derivatives PLURICHEMIE ANSTALT 26 March 1975 [27 March 1974 (2) 10 May 1975] 12608/75 Heading C2U The invention comprises compounds of formula wherein X is Cl or F, and either (i) R 1 is OH or C 1-16 acyloxy and R 2 is tetrahydropyran-2-yloxy, or (ii) R 1 is C 6-16 acyloxy and R 2 is OH, or (iii) R 1 and R 2 are each C 1-16 acyloxy. Preparation of I is from the corresponding 11, 17-diols by conversion to their 11-(tetrahydropyran-2-yl) ethers or 11-(di- or tri-chloro- or fluoro-acetates), followed as appropriate by 17-esterification, selective 11-hydrolysis (or solvolysis in the presence of silica gel) and 11- esterification. 21 - Deoxybeclomethasone and its 16α- epimer are prepared from their 9,11-epoxy analogues by reaction with HCl. 21 - Deoxybeclomethasone 11 - propionate is prepared from its 11-(tetrahydropyran-2-yloxy) analogue by reaction with EtCO 2 H. Anti-inflammatory compositions for oral, topical and parenteral administration comprise a compound I and a carrier.