baber/WOPTO huggingface dataset:
Patent CA-2945812-A1 (CA)
Title: Trail receptor agonists for treatment of fibrotic diseases
Inventor: LEE KANG CHOON
IPC: A61K38/17
Filed: 2015-04-17
Abstract: Pro-apoptotic agents such as ligands and agonists of agonistic TRAIL receptors can induce or increase apoptosis of cells that cause fibrosis and underlying diseases such as liver, pancreatic, lung and skin diseases characterized by fibrosis, cirrhosis, or complications thereof. The compositions and methods can be used to selectively remove activated hepatic stellate cells (HSCs), the originators of liver fibrosis and cirrhosis, and activated pancreatic stellate cells (PSCs), the originators of pancreas fibrosis and pancreatitis, and can be effective to reduce or prevent further chronic fibrosis by simultaneously reducing multiple fibrosis-associated molecules secreted or induced by such activated stellate cells. The compositions are typically effective to target agonistic TRAIL receptors such as TRAIL-R1/DR4 and TRAIL-R2/DR5 that are selectively expressed in activated HSCs and PSCs in physiological conditions. Ligands and agonists that can be used to target agonistic TRAIL receptors include, but are not limited to, TRAIL-R1/DR4 and/or TRAIL- R2/DR5 agonists.
Patent CA-2946770-A1 (CA)
Inventor: MISENER CHRISTOPHER PAUL HARRISON
IPC: G07D9/00
Filed: 2016-10-28
Abstract: Systems and methods are provided for processing coin deposits and withdrawals in an automated banking machine (ABM). In one aspect, a cash management system is described.  The cash management system includes a coin sorter for accepting and discriminating between a plurality of denominations of coin; at least one coin roller coupled to the coin sorter, for rolling the plurality of denominations of coin output by the coin sorter; at least one rolled coin store coupled to the at least one coin roller, for storing rolled coin in the plurality of denominations output by the at least one coin roller; and a rolled coin dispenser coupled to the at least one rolled coin store, for obtaining rolled coin requested in a withdrawal.
Patent CA-2946864-A1 (CA)
Title: Methods of diagnosis and treatment of celiac disease in children
Inventor: ANDERSON ROBERT P
IPC: A61P1/04
Filed: 2015-04-24
Abstract: Provided herein are compositions and methods for treating and/or identifying children having or suspected of having Celiac disease.
Patent CA-2947031-A1 (CA)
Title: Composes et compositions d'induction de la chondrogenese
Inventor: CHOI HA-SOON
IPC: A61K31/351
Filed: 2015-05-12
Abstract: La présente invention concerne des composés de formule (I): ou un sel, un tautomère ou un stéréoisomère pharmaceutiquement acceptable de ceux-ci, les variables étant telles que définies dans la description. La présente invention concerne en outre des compositions pharmaceutiques comprenant de tels composés, et des méthodes d'utilisation de tels composés pour le traitement d'une lésion articulaire ou d'une blessure articulaire chez un mammifère, et pour induire la différenciation de cellules souches mésenchymateuses en chondrocytes.
Patent CA-2948595-A1 (CA)
Inventor: PARDAL FILIPE AUGUSTO EUGENIO
IPC: A61P25/24
Filed: 2014-05-09
Abstract: The present invention provides pharmaceutically acceptable salts of enantiomerically pure(R)-pirlindole and (S)-pirlindole compounds having an increased bioavailability profile for use in medicine.
Patent CA-2948685-A1 (CA)
Title: Device for adjusting girth of waistband of pants or skirt
Inventor: PARK HAE OH
IPC: A41D1/06
Filed: 2016-07-07
Abstract: The present invention generally relates to a device for adjusting girth of a waistband of pants or a skirt, in which the device can efficiently adjust the girth of a waistband of pants or a skirt in response to body changes such as a weight gain or loss. To achieve the above-mentioned object, the device of the present invention is configured as described hereinbelow. The waistband of the pants or the skirt is divided into a front waistband and a rear waistband, and the front waistband overlaps the rear waistband at an end part of the rear waistband. A guide rail is fixed to the rear waistband, and the rear waistband and the front waistband are connected to each other, and a latch engaging with a rack part is mounted to a sliding member, wherein an elastic member is fitted over a hinge pin at a middle part thereof.
Patent CA-2948695-A1 (CA)
Inventor: SEEGER DIRK
IPC: C09D7/65
Filed: 2015-04-23
Abstract: The present invention relates to a coating composition comprising at least one binder (A) comprising at least one polymeric resin (A1) and at least one crosslinking agent (A2), at least one anticorrosion pigment (B), and at least one organic solvent (C), where (B) is an alloy of Zn and Mg and optionally at least one further metal and/or semimetal, the coating composition having a pigment volume concentration (PVC) in a range from 5.0% to 25.0%, and comprising the anticorrosion pigment (B) in an amount in a range from 5.0 to 25.0 wt%, based on the total weight of the coating composition, to the use thereof for the at least partial coating of a metallic substrate with a primer coat, to a method for the at least partial coating of such a substrate with such a primer coat, to a substrate at least partially coated therewith, and to a component or article produced from such a substrate.
Patent CA-2948965-A1 (CA)
Inventor: BRENNAN DAVID J
IPC: C09D7/65
Filed: 2016-11-18
Abstract: The present invention relates to a compound which is a di- and/or a tristyrylphenol monoglycidyl ether adduct of the compound of Formula I: (see formula I) where m is from 1 to 60. The compound of the present invention is useful as an open time additive in coatings formulations.
Patent CA-2954050-A1 (CA)
Inventor: RIZZI ENRICO
IPC: F28F9/013
Filed: 2015-06-19
Abstract: Shell and tube heat exchanger (1) comprising a first outer shell (2) and a tube bundle (3), inlet and outlet interfaces communicating with the shell side and with the tube side for a first fluid and for a second fluid respectively, wherein the exchanger comprises a second shell (4) which is inside said first shell (2) and surrounds said tube bundle (3); said second shell (4) comprises at least one releasable longitudinal joint (32) and a plurality of longitudinal sections connected by releasable joints; said second shell (4) delimits the shell side of the exchanger (1)around said tube bundle (3), and further defines a flushing interspace (5) communicating with said shell side, said first fluid flows through said shell side along one or more longitudinal passages, and said first fluid and said second fluid are counter-current along said one or more longitudinal passages.
Patent CA-2955491-A1 (CA)
Inventor: HAMDOUN KARIM
IPC: B65D23/06
Filed: 2015-08-11
Abstract: A vented cap (30) adapted to accumulate an overflow of liquid from a reservoir (10) and vent gas from the reservoir to atmosphere. The vented cap includes an insert (35) and a shell (65). The insert includes a projection (50) extending longitudinally from a floor pan (40). The shell includes an outer skirt (70) joined to and extending longitudinally outwardly from the floor pan and is attached to a top (85). The top and the outer skirt define a headspace (90) between the floor pan and the top. The projection extends into a portion of the headspace and defines a projection aperture (60), allowing liquid and gas to flow into the headspace. The vented cap further includes a vent (100) in fluid communication between the headspace and atmosphere.
Patent CA-2957503-A1 (CA)
Title: Systeme de generation d'energie hydroelectrique a partir d'un canal a ecoulement hypocritique
Inventor: MALLIKARJUNA CHALLA BALAIAH
IPC: F02B9/00
Filed: 2015-08-04
Abstract: Cette invention concerne un système de génération d'énergie hydroélectrique à partir d'un canal à écoulement hypocritique. Ledit système comprend un canal de production d'énergie dévié à partir du canal à écoulement hypocritique pour générer de l'énergie hydroélectrique en modifiant un ou plusieurs paramètres d'écoulement de l'eau, ledit canal de production d'énergie comprenant une section d'admission, une ou plusieurs section(s) inclinée(s), une ou plusieurs section(s) de génération d'énergie et une section de récupération, un déversoir d'admission au niveau de la section d'admission du canal de génération d'énergie, reliant le canal à écoulement hypocritique au canal de génération d'énergie pour augmenter la vitesse de l'eau, ledit déversoir d'admission étant conçu sur la base d'une vitesse de décharge de l'eau à puiser à partir du canal à écoulement hypocritique, et un ensemble de turbines disposé dans le canal de génération d'énergie pour générer de l'énergie au moyen de l'eau déviée à partir du canal à écoulement hypocritique, le nombre des turbines dépendant de la longueur du canal de génération d'énergie.
Patent CA-2959712-A1 (CA)
Inventor: LI XIANFENG
IPC: A61K31/69
Filed: 2017-02-28
Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed. Such compounds have a structure which is: (see above formula) wherein X is H or F or OH; Y is selected from the group consisting of a bond, -O-, -S-, -NH-, substituted or unsubstituted alkylene, and substituted or unsubstituted heteroalkylene; and Z is a substituted or unsubstituted heterocyclic ring or ring system containing at least one endocyclic boron.
Patent CA-2962452-A1 (CA)
Title: Mountable display devices
Inventor: ZENOFF ANDREW
IPC: G06N5/04
Filed: 2015-07-28
Abstract: The present disclosure provides display devices and methods. A display device can include a visual curvilinear display mounted on a support member. A user may display or project media through the visual curvilinear display according to a display and/or location preference or schedule of the user. A controller in communication with said visual curvilinear display.
Patent CA-2964701-A1 (CA)
Title: Concepts de pivotement de tetes de coupe-bordures de pivotement a fil fixe
Inventor: ALLISS GEORGE E
IPC: A01D34/84
Filed: 2015-12-17
Abstract: L'invention concerne un ensemble tête de coupe-bordures destiné à être utilisé sur une machine de coupe de végétation. L'ensemble tête de coupe-bordures comporte un boîtier. Le boîtier a une surface supérieure, une surface inférieure, et peut avoir au moins deux zones en creux entre celles-ci. Des montants de pivot sont disposés autour de la tête de coupe-bordures. Un disque d'ancrage est disposé autour de chaque montant de pivot. Le disque d'ancrage est libre de tourner autour du montant de pivot à l'intérieur d'une plage. Chaque disque d'ancrage peut avoir deux canaux de fil de coupe-bordures s'étendant à travers celui-ci. Les deux canaux de fil de coupe-bordures sont joints par une rainure de bord ouvert qui s'étend le long d'un bord. Une longueur de fil de coupe-bordures est prévue pour chaque disque d'ancrage. Chaque longueur de fil de coupe-bordures a une première extrémité qui s'étend à travers le premier des canaux de fil de coupe-bordures, une seconde extrémité qui s'étend à travers le second des canaux de fil de coupe-bordures, et un coude qui se loge dans la rainure de bord ouvert.
Patent CA-2965499-A1 (CA)
Title: Systems and methods for clinical decision support and documentation
Inventor: PHILLIPS RICHARD C
IPC: G06F19/00
Filed: 2015-10-23
Abstract: Various implementations of methods and systems for computing a patient-specific medical report associated with a diagnosis and generating supporting documentation for the report are described in this disclosure. In some implementations, the medical documentation system can assist doctors in providing care to hospitalized patients. In some implementations, the medical documentation system can generate a patient-specific appeal letter in response to a medical claim denial. Results of patient data input into evidence-based models can be presented to a user thorough a graphical user interface (GUI), which can also allow the user to interact with the medical documentation system. In some implementations, the medical documentation system can generate an interactive graphical user interface (GUI) that can be used to analyze patient data.
Patent CA-2965699-A1 (CA)
Title: Application command control for small screen display
Inventor: SETO JULIE
IPC: G06F9/44
Filed: 2015-11-05
Abstract: Examples of the present disclosure describe application command control for small screen display. When detecting a display width associated with a processing device is equal to or less than a threshold value, the processing device launches an application command control programmed for display on small screens. The application command control interfaces with an application and comprises a plurality of top-level palettes and a plurality of drill-in palettes programmed for the application. A top-level palette for the application is vertically scrollable and comprises a collection of rows comprising one or more selectable command elements. A row of the one or more command elements of the top-level palette comprises a drill-in feature that when selected presents a drill-in palette. A drill-in palette is vertically scrollable and comprises one or more rows of selectable command elements.
Patent CA-2966963-A1 (CA)
Title: Procede et systeme servant a surveiller et a communiquer la vitesse de remplissage d'un recipient
Inventor: KEKALAINEN FREDRIK
IPC: G06Q10/00
Filed: 2015-10-26
Abstract: L'invention concerne un procédé servant à surveiller une vitesse de remplissage d'un récipient et à communiquer la vitesse de remplissage surveillée à un serveur, le récipient comportant au moins un premier capteur qui est un capteur de vitesse de remplissage dans un mode normalement non actif. Le procédé comporte l'étape consistant à recevoir un modèle de fonctionnement en provenance d'un serveur, le modèle de fonctionnement définissant un signal de réveil pour déterminer s'il faut initialiser une communication entre le capteur de vitesse de remplissage et le serveur, le modèle de fonctionnement définissant également un niveau prédéterminé de vitesse de remplissage comportant une valeur maximale prédéfinie de la vitesse de remplissage et/ou une valeur minimale prédéfinie de la vitesse de remplissage, dans lequel la communication entre le capteur de vitesse de remplissage et le serveur se produit uniquement quand le niveau prédéterminé de la vitesse de remplissage n'est pas satisfait ; l'étape consistant à détecter le signal de réveil ; l'étape consistant à mesurer la vitesse de remplissage du récipient au moyen du capteur de vitesse de remplissage ; l'étape consistant à comparer une vitesse de remplissage mesurée par rapport au niveau prédéterminé de la vitesse de remplissage défini dans le modèle de fonctionnement ; et l'étape consistant à communiquer la vitesse de remplissage mesurée au serveur uniquement si la vitesse de remplissage mesurée est égale ou supérieure à la valeur maximale prédéfinie de la vitesse de remplissage, et/ou si la vitesse de remplissage mesurée est égale ou inférieure à la valeur minimale prédéfinie de la vitesse de remplissage.
Patent CA-2967173-A1 (CA)
Inventor: CIRIO GABRIEL
IPC: G06F17/50
Filed: 2015-11-10
Abstract: La méthode consiste à: - récupérer la distribution des fils (1) de chaîne, des fils de trame (2) et des nuds (3) de croisement des fils; - décrire chaque nud (3) de croisement de fils par une coordonnée (x) de position 3D et deux coordonnées de glissement, la coordonnée (u) de glissement de chaîne et la coordonnée (v) de glissement de trame, qui représentent le glissement des fils de chaîne (1) et de trame (2); - mesurer les forces de chaque nud (3) de croisement des fils sur la base d'un modèle de force, les forces étant mesurées tant au niveau de la coordonnée de position (x) qu'au niveau des coordonnées (u,v) de glissement; - calculer le mouvement de chaque nud (3) de croisement des fils au moyen d'équations de mouvement dérivées qui font appel aux équations de Lagrange-Euler, et sont intégrées de manière numérique avec le temps, les équations de mouvement représentant la densité de masse répartie de manière uniforme le long des fils, ainsi que les forces mesurées et les conditions limites.
Patent CA-2969483-A1 (CA)
Inventor: SOMMERVOGEL LAURENT
IPC: G01K7/16
Filed: 2015-10-15
Abstract: Le procédé utilise au moins : - une ligne (22) composée d'au moins deux conducteurs isolés par un matériau dont l'impédance d'isolement (24) dépend localement de la température, ladite ligne parcourant ladite installation; - un réflectomètre (21 ) transmettant périodiquement un signal de réflectométrie à une extrémité de ladite ligne, ledit signal se propageant le long de ladite ligne, ledit réflectomètre mesurant les échos reçus et comparant les amplitudes desdits échos avec une référence donnée; un point chaud étant détecté lorsque les amplitudes d'un nombre donné d'échos successifs sont supérieures à ladite référence donnée, lesdits échos étant provoqués par une diminution locale de la valeur de ladite impédance d'isolement (24).
Patent CA-2969934-A1 (CA)
Inventor: LABERGE MICHEL GEORGES
IPC: H05H1/00
Filed: 2016-01-14
Abstract: Examples of system for generating vortex cavity are disclosed. The system comprises a vessel into which a fluid is injected through one or more inlet ports and a fluid circulating system configured to circulate the fluid through the vessel such that the fluid is removed from the vessel through an outlet port and is returned back into the vessel through the one and more inlet ports. A first spinner is mounted at one wall of the vessel while a second spinner is mounted at the opposite wall of the vessel such that the second spinner is at some distance away from the first spinner and it faces the first spinner. When the fluid circulating system starts circulating the fluid within the vessel a vortex cavity is formed that extends between the first and the second spinners so that one end of the vortex cavity sits on the first spinner while the opposite end of the vortex cavity sits on the second spinner.
Patent CA-2970051-A1 (CA)
Title: Radio frequency circuit, transmitter, base station, and user terminal
Inventor: WANG LIANGFANG
IPC: H03F1/07
Filed: 2014-12-11
Abstract: Embodiments of the present invention provide a radio frequency circuit, including: a first circuit and a second circuit. The first circuit is configured to: receive a first signal and a second signal; split the first signal into a third signal and a fourth signal, and split the second signal into a fifth signal and a sixth signal; adjust a phase of the fifth signal to obtain a seventh signal; and combine the seventh signal and the third signal into an eighth signal. The second circuit includes a primary power amplifier branch and a secondary power amplifier branch, the primary power amplifier branch includes an outphasing circuit, the secondary power amplifier branch includes a secondary power amplifier, the primary power amplifier branch is configured to process the fourth signal and the sixth signal, and the secondary power amplifier branch is configured to process the eighth signal. In the radio frequency circuit provided in the embodiments of the present invention, the second circuit at rated power can reach highest efficiency, so that an actual application requirement can be satisfied.
Patent CA-2970916-A1 (CA)
Inventor: WOODWARD ROBERT
IPC: C12Q1/68
Filed: 2015-03-13
Abstract: The present disclosure relates to methods of monitoring the status of an allograft in a transplant recipient, as well as to methods of monitoring and adjusting immunosuppressive therapies being administered to the transplant recipient.
Patent CA-2972148-A1 (CA)
Title: Composes benzazepine dicarboxamide
Inventor: HOVES SABINE
IPC: C07D223/16
Filed: 2016-03-03
Abstract: La présente invention concerne de nouveaux composés benzazépine dicarboxamide de formule (I) dans laquelle R1 à R4 sont tels que définis dans la description et dans les revendications, ainsi que des sels pharmaceutiquement acceptables de ceux-ci. Lesdits composés sont des agonistes de TLR et peuvent par conséquent être utiles comme médicaments pour le traitement de maladies telles que le cancer, les maladies auto-immunes, l'inflammation, le sepsis, l'allergie, l'asthme, le rejet de greffe, la réaction du greffon contre l'hôte, les immunodéficiences et les maladies infectieuses.
Patent CA-2974512-A1 (CA)
Title: Polymeric viscosifiers for use in water-based drilling fluids
Inventor: GALINDO KAY ANN
IPC: C09K8/04
Filed: 2015-03-31
Abstract: Systems and methods for drilling in a subterranean formation are disclosed. A method comprises providing a drilling fluid, wherein the drilling fluid comprises an aqueous fluid; a first polymer comprising 2-acrylamido-2-methylpropane sulfonic acid, vinylpyrrolidinone, pentaerythritol allyl ether, and methylenebisacrylamide; and a second polymer comprising acrylate, 2-acrylamido-2-methylpropane sulfonic acid, methacrylic acid, and allyloxy 2-hydroxy propane sulfonic acid. The method further comprises placing the drilling fluid into the subterranean formation and drilling a wellbore in the subterranean formation.
Patent CA-2976986-A1 (CA)
Inventor: LIU JIANQIU
IPC: H04N17/00
Filed: 2016-01-28
Abstract: Provided is an interference signal recording device, and a system and method using the device to locate a fault point of a cable television network, the method comprising: disposing an interference signal recording device at a front end of the cable television network, and disposing via a signal coupler another interference signal recording device on a cable branch of the cable television network, wherein both interference signal recording devices have a sampler; upon receipt of a pre-specified sampling timing signal from among downstream signals, sampling, by each of the interference signal recording devices, an interference signal; obtaining, by a computer and via the internet, two digital sampling value sequences of the interference signals sampled by the interference signal recording devices, and calculating a cross-correlation function of the two digital sampling value sequences; and determining, according to whether cross-correlation peaks caused by a fault point are present in a cross-correlation function image of the calculation result, whether a fault point is present on a signal transmission path at an installation location of a downstream signal coupler.
Patent CA-2980443-A1 (CA)
Inventor: SHLUZAS ALAN E
IPC: A61M5/31
Filed: 2015-04-24
Abstract: One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.