baber/WOPTO huggingface dataset:
Patent CA-3115680-A1 (CA)
Title: Conjugues anticorps-medicament (adc) a region fc mise sous silence et utilisations associees
Inventor: PALCHAUDHURI RAHUL
IPC: C07K16/28
Filed: 2019-10-23
Abstract: L'invention concerne des anticorps et des conjugués anticorps-médicament ayant une région Fc avec des substitutions conduisant essentiellement à une région Fc silencieuse. Les anticorps et les conjugués anticorps-médicament décrits ici sont utiles pour la déplétion de cellules et pour le traitement de diverses maladies hématopoïétiques, de troubles métaboliques et de cancers, par exemple de la leucémie myéloïde aiguë (AML), et de maladies auto-immunes, entre autres. Les compositions et les procédés décrits ici peuvent être utilisés pour traiter un trouble directement, par exemple, par déplétion d'une population de cellules auto-immunes CD45+ ou de cellules cancéreuses CD45+ ou CD117+. Les compositions et les procédés décrits ici peuvent également être utilisés pour préparer un patient pour une thérapie par greffe de cellules souches hématopoïétiques et pour améliorer la prise de greffes de cellules souches hématopoïétiques par déplétion sélective de cellules souches hématopoïétiques endogènes avant la procédure de transplantation.
Patent CA-3118095-A1 (CA)
Inventor: PRIESTAS JAMES ROBERT
IPC: G06N3/02
Filed: 2021-05-11
Abstract: An Artificial Intelligence (Al) based document processing system receives a request including one or more of a message and documents related to a process to be automatically executed. A process identifier is extracted and used for retrieving guidelines for the automatic execution of the document processing task. Machine Learning (ML) models, each corresponding to a guideline, are used to extract data responsive to the guidelines. Based on the responsive data meeting the approval threshold and the automatic document processing task executed, one or more of a recommendation to accept or reject the request, and a corresponding letter can be automatically generated.
Patent CA-3119585-A1 (CA)
Inventor: MORIN CAMILLE
IPC: E06B3/663
Filed: 2019-11-05
Abstract: The invention relates to an insulating glazing unit (1) forming a window or door opening panel, which is frameless around at least a part of its perimeter and which comprises at least two panes of glass (3, 4) that are spaced apart in pairs by a left-hand and a right-hand vertical spacer (2) that are made of glass and disposed respectively close to the left-hand and right-hand edges of the glass panes, and an upper and a lower horizontal spacer (5) that are made of a material other than glass and are disposed respectively close to the upper and lower edges of the glass panes. The insulating glazing unit also comprises, between each face of the horizontal spacers that is turned toward the outside of the insulating glazing unit and the edge of the glass panes, a metal profiled element (7), at least one end of the lower metal profiled element being fastened at least to the two glass panes by virtue of a structural adhesive. The invention makes it possible to provide an insulating glazing unit forming a window or door opening panel, which is frameless around at least a part of its perimeter, has good mechanical integrity and is shock resistant in spite of the spacers made of different materials.
Patent CA-3121178-A1 (CA)
Title: Dispenser latching system
Inventor: CUNEFARE KENNETH A
IPC: A47K5/06
Filed: 2019-12-04
Abstract: A dispenser comprising a body with a front side and a back side with the front side movably attached to the back side by a hinge, wherein the hinge includes pin receiving openings and the hinge is configured to move the front side between an open position and a closed position; and a locking device including pins and a pin housing for each of the pins and being configured to allow respective movement of the pins between a first pin position and a second pin position; and a dispenser key configured to magnetically move the pins from the first pin position to the second pin position to allow the front side to move from the closed position to the open position.
Patent CA-3122799-A1 (CA)
Title: Systems and methods for producing parts at elevated temperatures
Inventor: SUSNJARA KENNETH
IPC: B29C64/165
Filed: 2021-06-18
Abstract: A mold assembly for producing a part includes a first section, a second section movably coupled to the first section, and a cavity defined by the first section and the second section, the cavity being shaped to receive a part while the first section and the second section are movably coupled to each other. The mold assembly includes a joint formed by adjacent surfaces of the first section and the second section and a seal extending along the joint.
Patent CA-3123833-A1 (CA)
Title: Cyclic amine derivative as agent for promoting advillin function, and novel cyclic amine derivative and pharmaceutical use thereof
Inventor: NISHIMURA KAZUMI
IPC: A61K31/454
Filed: 2019-12-26
Abstract: The present invention addresses the problem of providing an advillin function promoter that comprises a low-molecular compound and is useful for treating neuroaxonal injury. The present invention provides an advillin function promoter that comprises, as an active ingredient, a cyclic amine derivative typically represented by chemical formula or a pharmacologically acceptable salt thereof.
Patent CA-3124621-A1 (CA)
Title: Novel fish coronavirus
Inventor: NYLUND STIAN
IPC: C12N15/50
Filed: 2020-02-04
Abstract: The invention relates to a novel fish virus, indicated to be a Coronavirus, which causes mortality in fish, and to methods of detecting said virus in fish, and related uses.
Patent CA-3127044-A1 (CA)
Inventor: CROOYMANS BRENNAN
IPC: A01C7/20
Filed: 2019-04-23
Abstract: ABSTRACT A singulating meter includes a seed disc with seed apertures rotates in a vertical plane through a seed reservoir. A horizontal seed tube has an inlet adjacent to the top of the seed disc and the seed apertures move along a seed aperture path toward the inlet. Pressurized air flows into the tube inlet, and through each seed aperture as it rotates upward out of the seed reservoir pushing a seed into each seed aperture which seed then moves along the seed aperture path through about 180 degrees of rotation to a release position at the top of the path where the seed is carried horizontally into the seed tube. An ejector pushes debris out of the seed apertures into the seed tube. Art alignment guide moves the singulator element of the meter into the operating position where same is magnetically secured. 25RR I 245v I Date Recue/Date Received 2021-08-04
Patent CA-3128502-A1 (CA)
Inventor: LI HAN
IPC: A61P35/00
Filed: 2020-02-03
Abstract: L'invention concerne des anticorps qui se lient spécifiquement à la molécule de jonction étroite humaine CLDN18.2 et ont des propriétés fonctionnelles qui les rendent appropriés pour une utilisation dans des immunothérapies à base d'anticorps d'une maladie associée à une expression aberrante de CLDN18.2.
Patent CA-3129518-A1 (CA)
Title: Mobile battery powered beverage distribution cart
Inventor: ALOBAIDI MOHAMMED
IPC: F25D11/00
Filed: 2020-02-21
Abstract: Disclosed herein are various mobile battery powered beverage distribution and marketing carts, kiosks, systems, and methods for operating, transporting, charging, maintaining, optimizing, and storing these mobile battery powered beverage distribution and marketing carts. The mobile battery powered beverage carts may generally comprise a wheeled base, upper workstation, at least one storage and/or refrigerated compartment, a battery, and a large viewing screen for displaying marketing and/or entertainment content thereon. The battery within the cart is configured to operate any electrical componentry on the cart, so that the cart can be independently operable away from any electrical wall outlets. These carts can be customized with any number of options or accessories to meet particular demands and be temporarily deployed to areas where demand, or crowd size, is highest.
Patent CA-3129602-A1 (CA)
Inventor: UHL ALBERT
IPC: F16B7/02
Filed: 2019-02-13
Abstract: L'invention concerne une douille de raccordement (1) et/ou une barre de traction-compression (2) comprenant au moins une douille de raccordement (1) comprenant un corps de base (3), une section d'accouplement (4) réalisée ou disposée sur la périphérie extérieure du corps de base (3) et un orifice de passage (5), la barre de traction-compression (2) présentant un premier joint d'étanchéité (6) qui assure l'étanchéité d'un espacement formé entre le corps de base (3) et un corps tubulaire (26), et la barre de traction-compression (2) présentant un deuxième joint d'étanchéité (7) qui referme au moins l'orifice de passage (5), le corps tubulaire (26) présentant sur sa périphérie intérieure au moins une section de contre-accouplement (27) correspondant à la section d'accouplement (4) de la douille de raccordement (1), l'au moins une douille de raccordement (1) et le corps tubulaire (26) étant, dans la position de montage, au moins en partie directement adjacents l'un à l'autre dans une zone de contact (28) formée par la section d'accouplement (4) et la section de contre-accouplement (27) et la zone de contact (28) étant rendue étanche vers l'extérieur par le premier joint d'étanchéité (6) et le deuxième joint d'étanchéité (7), de telle sorte qu'aucune humidité ne pénètre dans la zone de contact (28).
Patent CA-3132437-A1 (CA)
Inventor: THORSEN MITCHEL
IPC: A24F40/465
Filed: 2020-03-09
Abstract: L'invention concerne des dispositifs de fourniture d'aérosol. Un tel dispositif comprend un réceptacle conçu pour recevoir un matériau de génération d'aérosol (110), le réceptacle comprenant un suscepteur (132) qui peut être chauffé par pénétration par un champ magnétique variable. Le dispositif comprend en outre un élément isolant (128) s'étendant autour du suscepteur, l'élément isolant étant positionné à distance du réceptacle pour fournir un entrefer (202) autour du suscepteur. Le dispositif comprend en outre une bobine d'induction (224) s'étendant autour de l'élément isolant de telle sorte que l'élément isolant soit positionné entre la bobine d'induction et le suscepteur, la bobine d'induction étant conçue pour générer le champ magnétique variable. Un autre dispositif de fourniture d'aérosol de ce type comprend : un suscepteur conçu pour recevoir un matériau de génération d'aérosol, le suscepteur pouvant être chauffé par pénétration par un champ magnétique variable ; un élément isolant s'étendant autour du suscepteur, l'élément isolant étant positionné à distance du suscepteur ; une bobine d'induction s'étendant autour de l'élément isolant de telle sorte que l'élément isolant soit positionné entre la bobine d'induction et le suscepteur, la bobine d'induction étant conçue pour générer le champ magnétique variable ; et un couvercle externe (102) formant au moins une partie d'une surface externe du dispositif de fourniture d'aérosol, une surface interne du couvercle extérieur étant positionnée à distance d'une surface externe du suscepteur d'une distance comprise entre environ 4 mm et environ 10 mm.
Patent CA-3133564-A1 (CA)
Inventor: EL TAWY DALIA
IPC: F02C6/00
Filed: 2019-07-16
Abstract: System for hydraulic fracturing is provided. The system may involve a mobile hydraulic fracturing subsystem including a variable frequency drive (VFD) (12) electrically coupled to a generator (50). An electric motor (14) is driven by VFD (12). Harmonic mitigation circuitry (16) is configured to mitigate harmonic distortion by VFD (12). A hydraulic pump (20) is driven by motor (14) to deliver a pressurized fracturing fluid. VFD (12), harmonic mitigation circuitry (16), motor (14) and hydraulic pump (20) may be arranged on a mobile platform (24) so that a subsystem so arranged can be transportable from one physical location to another. In some disclosed embodiments, the hydraulic fracturing subsystem may be fitted on mobile platform (24) having size and weight not subject to laws or regulations requiring a permit and/or accompaniment by an escort vehicle to travel on a public highway, such as public highways in the United States and/or Canada.
Patent CA-3134249-A1 (CA)
Title: Adjustable packaging machine
Inventor: WEGNER THOMAS
IPC: B65B11/00
Filed: 2021-10-13
Abstract: An unwind station for a packaging machine may be configured to form wrappers having different sizes from a web of packaging material and supply the wrapper to a wrapping station. The unwind station may include a base configured to support the web of packaging material and a carriage configured to selectively slide in a longitudinal direction on the base. A rotating blade can be configured to periodically score the web to form a break line extending between lateral sides of the web. A first conveyor arm and a second conveyor arm may project longitudinally outward from the carriage. The first conveyor arm and the second conveyor arm can each include a low-speed conveyor configured to transport the web to a high-speed conveyor. The high-speed conveyor is configured to separate the wrapper from the web as the break line passes a shear point between the low-speed conveyors and the high-speed conveyors.
Patent CA-3135228-A1 (CA)
Inventor: FIELD RYAN
IPC: A61B5/00
Filed: 2020-04-09
Abstract: An exemplary photodetector system includes a plurality of photodetectors connected in parallel and a processor communicatively coupled to the plurality of photodetectors. The processor is configured to receive an accumulated output from the plurality of photodetectors. The accumulated output represents an accumulation of respective outputs from each of the plurality of photodetectors detecting photons during a predetermined measurement time period that occurs in response to a light pulse being directed toward a target within a body. The processor is further configured to determine, based on the accumulated output, a temporal distribution of photons detected by the plurality of photodetectors, and generate, based on the temporal distribution of photons, a histogram representing a light pulse response of the target within the body.
Patent CA-3135452-A1 (CA)
Title: Procede de production d'acide methanesulfonique anhydre a partir de methane et de so3
Inventor: BORGMEIER FRIEDER
IPC: C07C303/44
Filed: 2020-04-14
Abstract: La présente invention concerne un procédé de fabrication d'acide méthanesulfonique anhydre (MSA) ainsi que de l'acide méthanesulfonique fabriqué par ledit procédé et ses utilisations.
Patent CA-3138349-A1 (CA)
Inventor: VERHOEVEN JONAS
IPC: C07D493/04
Filed: 2020-06-11
Abstract: La présente invention concerne de nouveaux intermédiaires spirobicycliques utiles dans la synthèse d'analogues de nucléosides spirobicycliques.
Patent CA-3140313-A1 (CA)
Inventor: STRATULATE GARY WARREN
IPC: F04B5/02
Filed: 2021-11-24
Abstract: Embodiments provide for a double acting fluid end that may be used in high pressure fluid handling equipment, wherein the fluid end has an arrangement that acts upon both a suction and a discharge operation.
Patent CA-3140861-A1 (CA)
Inventor: CULBERTON NICHOLAS T
IPC: G16H20/13
Filed: 2020-06-10
Abstract: Various aspects described herein relate to presenting drug dispensing information. Data related to a plurality of dispensing events initiated by one or more employees, of an electronic drug dispensing system can be received. A set of dispensing events of the plurality of dispensing events can be determined as constituting possible misappropriation of drugs by the one or more employees. An alert related to the set of dispensing events can be provided based on determining that the set of dispensing events constitute possible misappropriation of drugs.
Patent CA-3141613-A1 (CA)
Title: Pre-vaporizing pipe, combustion assembly provided therewith and turbomachine provided therewith
Inventor: SAVARY NICOLAS ROLAND GUY
IPC: F23R3/32
Filed: 2020-05-25
Abstract: The invention relates to a pre-vaporizing pipe (5) for a combustion chamber of a turbomachine, comprising a generally elongate main body (50), comprising a first end portion (51) delimiting an inlet duct (52) in which a fuel injector is to be mounted, the body (50) having an external surface (500) having a first length (L1) that extends from the portion (51) to at least one first fuel outlet end piece (53), and a second length (L2) that extends the first length (L1) from the end piece (53) and that extends from the end piece (53) to a second fuel outlet end piece (54). According to the invention, inside the body (50) there is a first channel (55) connecting the duct (52) to the end piece (53) and a second channel (56) which is distinct from the first channel (55) and which connects the duct (52) to the end piece (54).
Patent CA-3142104-A1 (CA)
Title: Heatshield for a gas turbine engine
Inventor: DENISOVA KSENIA
IPC: F01D25/24
Filed: 2020-05-20
Abstract: A heatshield for a gas turbine engine, comprising a main body having a leading edge, a trailing edge, lateral edges, a first surface and a second surface. The first surface being exposed to a hot working gas in use passing through the gas turbine engine. The heatshield having a leading hook and a trailing hook each extending between the lateral edges, the leading hook and the trailing hook extending from the second surface. A stiffening structure extending from the leading hook to the trailing hook and free from direct contact or attachment to the second surface.
Patent CA-3147271-A1 (CA)
Inventor: ALAM JOHN JAHANGIR
IPC: A61K31/4545
Filed: 2020-07-12
Abstract: The present invention provides methods and compositions for treatment of Dementia with Lewy Bodies.
Patent CA-3149203-A1 (CA)
Title: Soybean variety 5pcrv00
Inventor: KALVIG ANDREA BETH
IPC: C12N5/04
Filed: 2022-02-17
Abstract: A novel soybean variety, designated 5PCRV00 is provided. Also provided are the seeds of soybean variety 5PCRV00, cells from soybean variety 5PCRV00, plants of soybean 5PCRV00, and plant parts of soybean variety 5PCRV00. Methods provided include producing a soybean plant by crossing soybean variety 5PCRV00 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PCRV00, methods for producing other soybean varieties or plant parts derived from soybean variety 5PCRV00, and methods of characterizing soybean variety 5PCRV00. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PCRV00 are further provided.
Patent CA-3150809-A1 (CA)
Title: Procede de fabrication additive d'un produit, dispositif de fabrication et forme posologique pharmaceutique solide
Inventor: BOGDAHN MALTE
IPC: B29C64/153
Filed: 2020-08-07
Abstract: La présente invention concerne un procédé de fabrication additive d'un produit comprenant une étape d'agencement de couche, moyennant quoi une couche (11) de petites particules (12) d'un matériau de produit est agencée, ledit procédé comprenant en outre une étape de solidification au cours de laquelle un faisceau laser (3) est dirigé sur des points prédéfinis (8, 9, 10) à l'intérieur de la couche (11) de petites particules (12) pour chauffer et raccorder les petites particules (12) du matériau de produit au niveau desdits points (8, 9, 10), ce qui permet d'obtenir au moins une zone solidifiée de matériau de produit à l'intérieur de la couche (11) de petites particules (12). Le produit est fabriqué en réalisant de manière répétée l'étape d'agencement de couche et l'étape de solidification, moyennant quoi chaque zone solidifiée de matériau de produit de la couche actuelle (11) est raccordée à une partie précédemment solidifiée du produit jusqu'à ce que le produit soit généré par des zones solidifiées interconnectées de matériau de produit raccordé. Dans l'étape de solidification, le faisceau laser (3) est divisé en au moins deux sous-faisceaux séparés (4) qui sont dirigés sur des points séparés (8, 9, 10) pour raccorder simultanément les petites particules (12) du matériau de produit au niveau de ces points séparés (8, 9, 10). Les au moins deux sous-faisceaux séparés (4) sont dirigés sur des points séparés (8, 9, 10) à une certaine distance l'un de l'autre.
Patent CA-3151188-A1 (CA)
Title: Multiple heatsink cooling system for a line voltage thermostat
Inventor: BRAVARD LIONEL
IPC: G05D23/19
Filed: 2015-07-03
Abstract: A line voltage thermostat having a multiple heatsink switch. A total switch may have a semiconductor switch mounted on each heatsink of the multiple heatsink switch.  The semiconductor switches of the respective heatsinks may be connected in parallel to represent the total switch. Each of the two or more heatsinks, having a semiconductor switch for switching, and in total conveying the same power as one equivalent switch with one total heatsink, may have higher maximum operating temperatures and higher thermal resistances than twice the thermal resistance of the one total heatsink. The two or more heatsinks may be situated within a housing of the line voltage thermostat, and be easier to distribute in the housing to achieve an efficient layout of a display and control buttons for the thermostat.
Patent CA-3153869-A1 (CA)
Inventor: SHEPHERD JUSTIN
IPC: B65D88/30
Filed: 2020-11-02
Abstract: Un récipient de stockage ondulé comprend une section boîte dotée d'une paroi supérieure, de parois latérales ondulées et de parois d'extrémité, une section conique en entonnoir s'étendant vers le bas à partir de la section boîte et un cadre supportant la section boîte et la section en entonnoir. Le cadre comprend des montants verticaux qui sont joints d'un seul tenant à la section boîte et à une section base formée sur l'extrémité inférieure des montants verticaux et supportant la section en entonnoir. La configuration du récipient de stockage ondulé fournit environ 600 pieds cubes de volume intérieur clos permettant de stocker entre 50 000 et 51 000 livres de matériau en vrac.
Patent CA-3154754-A1 (CA)
Title: 2'-deoxy-2',2'-difluorotetrahydrouridines with high purity and methods of making the same
Inventor: ZUEND GEMMA
IPC: C07H1/00
Filed: 2020-10-07
Abstract: The invention relates to methods of synthesizing 2'-deoxy-2',2'-difluorotetrahydrouridine with increased purity and uniform particle size distribution. In particular, methods of the invention include crystallization and isolation procedures rendering synthetic reaction intermediates. The invention further includes compositions comprising the final compound in highly pure form, including lower number of impurities and lower levels of individual and total impurities.
Patent CA-3155451-A1 (CA)
Inventor: TYTGAT OLIVIER
IPC: C12Q1/6818
Filed: 2020-09-22
Abstract: La présente invention concerne le domaine de l'empreinte digitale de l'ADN, par exemple dans le domaine médico-légal. Plus particulièrement, la présente invention concerne un procédé de génotypage de polymorphismes, tels que des répétitions en tandem courtes, reposant sur les propriétés d'extinction de la fluorescéine de la guanine. Ainsi, le degré de complémentarité entre un échantillon d'ADN amplifié et une sonde spécifiquement conçue, peut être évalué par mesure de l'intensité de fluorescence du fluorophore fixé à la sonde lors de l'hybridation ou de la fusion. Les sondes et le procédé de la présente invention sont bien appropriés pour être utilisés dans un dispositif portable, un dispositif d'analyse d'ADN moins coûteux et peut être appliqué dans d'autres domaines que la médecine légale, comme la fraude alimentaire, le diagnostic et de nombreux autres.