baber/WOPTO huggingface dataset:
Patent CA-2365901-A1 (CA)
Title: Tissue-specific and pathogen-specific toxic agents and ribozymes
Inventor: DOLAN JOSEPH
IPC: C12N7/00
Filed: 2000-04-14
Abstract: The present invention relates to the discovery, identification and characterization of toxic agents which are lethal to pathogens and methods for targeting such toxic agents to a pathogen or pathogen infected cells in order to treat and/or eradicate the infection. In particular, the present invention relates to toxic agents which target bacteria at different stages of the bacterial life cycle, which are delivered alone or in combination to bacteria or bacteria-infected cells. The invention relates to toxic agents which are lethal to diseased cells and methods for targeting such toxic agents to a diseased cell in order to treat and/or eradicate the disease. The present invention relates to promoter elements which are pathogen-specific or tissue-specific and the use of such promoter elements to achieve pathogen-specific or tissue-specific expression of the toxic agent(s) and/or ribozyme(s) of the present invention. Specifically, the invention relates to the delivery of one or more toxic gene products, antisense RNAs, or ribozymes, or combination thereof. The invention provides a novel system by which multiple pathogenic targets may be simultaneously targeted to cause the death of a pathogen, or cell infected with a pathogen. Further, the invention has important implications in the eradication of drug-resistant bacterium and bacterial pathogens. The invention provides a novel system by which multiple targets may be simultaneously targeted to cause the death of a diseased cell. The invention has important implications in the eradication of drug-resistant pathogens (such as antibiotic resistant bacteria) and drug-resistant diseased cells (such as drug-resistant cancer cells).
Patent CA-2369541-A1 (CA)
Title: Pesticidal tetrazole derivatives
Inventor: DEKEYSER MARK ACHIEL
IPC: C07D257/04
Filed: 2000-03-28
Abstract: Tetrazole derivatives of formula (I) wherein R is a substituted or unsubstituted phenyl group, hetercocyclic group, or benzo-fused heterocyclic group, which exhibit activity as insecticides and acaricides.
Patent CA-2370440-A1 (CA)
Title: Plastic drink-through cup lid with fold-back tab
Inventor: MAZZAROLO IVONIS M
IPC: B65D17/32
Filed: 2002-02-04
Abstract: A plastic drink-through lid of the type having a deck, a peripheral skirt, and a partially separable, preformed tab in the deck to form a drink-through hold which does not extend through the peripheral skirt. The tab has an upstanding thumb catch preformed thereon. The fold back hinge is formed in the deck immediately adjacent the tab and spaced less than about one-half of the lid radius from the periphery. This creates a very short throw which allows a user to open the tab and lock it back with the thumb of the same hand that is holding the cup.
Patent CA-2372016-A1 (CA)
Title: Turbine moving blade, turbine stationary blade, turbine split ring, and gas turbine
Inventor: TOMITA YASUOKI
IPC: F01D9/02
Filed: 2002-02-14
Abstract: The present invention provides a turbine moving blade, a turbine stationary blade, and a turbine split ring which are capable of restraining the deterioration and peeling-off of a thermal barrier coating easily and surely, and a gas turbine capable of enhancing the energy efficiency by increasing the temperature of combustion gas. The turbine moving blade provided in a turbine constituting the gas turbine includes a platform having a gas path surface extending in the combustion gas flow direction, and a blade portion erecting on the platform. The thermal barrier coating covering the gas path surface is formed so as to go around from the gas path surface to an upstream-side end face and a downstream-side end face of the outer peripheral faces of the platform.
Patent CA-2373346-A1 (CA)
Title: Alliage metallique a point de fusion eleve a forte tenacite et resistance
Inventor: TAKADA JUN
IPC: C22C1/04
Filed: 2000-07-07
Abstract: L'invention porte sur le matériau d'un alliage métallique à point de fusion élevé obtenu par un procédé dans lequel l'élément métallique destiné à former un nitrure constituant l'un des composants d'une solution solide du matériau formant l'alliage, et dont la phase principale est faite de Mo, de W ou de Cr, est soumis à une nitruration interne à basse température correspondant à sa température de recristallisation la plus élevée ou moins, puis on lui incorpore des particules ultrafines de nitrure qui y sont dispersées, ce qui accroît la température de recristallisation la plus basse du matériau formant l'alliage, puis on soumet le matériau nitruré intérieurement à une deuxième nitruration à sa température de recristallisation la plus basse ou plus pour y développer des particules précipités ultrafines de nitrure, le côté surface du matériau conservant la texture de déformation de la phase principale et formant une structure stabilisée. L'alliage présente nettement une ténacité et une résistance améliorées.
Patent CA-2374072-A1 (CA)
Title: Modular hip prosthesis
Inventor: FERNANDEZ JOSE
IPC: A61F2/30
Filed: 2001-03-13
Abstract: A modular hip prosthesis, comprising: (a) a proximal segment including a neck lockingly engageable with a femoral head component and a male tapered portion; (b) a distal segment having a proximal end and a distal tip, the distal segment further formed with a male tapered portion adjacent the proximal end thereof; and (c) a metaphyseal segment having a proximal end and a distal end, the metaphyseal segment preferably including a bone engaging outer surface portion, and further including an axial bore therethrough, the axial bore including first and second female tapered portions formed adjacent the proximal and distal ends thereof, respectively. The first female tapered portion of the metaphyseal segment is dimensionally configured to lockingly engage the male tapered portion of the proximal segment. The second female tapered portion of the metaphyseal segment is dimensionally configured to lockingly engage the male tapered portion of the distal segment. Optionally, a screw dimensionally configured to pass through aligned bores in the proximal, metaphyseal and distal segments is threadably engaged with a threaded bore formed in the proximal end of the distal segment.
Patent CA-2376228-A1 (CA)
Title: Autologous adoptive immunotherapy with primed antigen-specific t cells or b cells
Inventor: NEWELL MARTHA K
IPC: A61K39/395
Filed: 2000-06-16
Abstract: The invention relates to methods and compositions for promoting antigen- specific immune responses with an appropriate cytokine bias. More specifically, the present invention relates to methods of using autologous adoptive immunotherapy with antigen-specific, ex vivo-primed T cells or B cells to promote antigen-specific immune responses with a Th1 or Th2 cytokine bias.
Patent CA-2376762-A1 (CA)
Title: Multiple protocol smart card communication device
Inventor: RIBEIRO CARLOS EDUARDO
IPC: H04L69/14
Filed: 2000-03-24
Abstract: A communication link is established between the smart card and a computer using a valid smart card communication protocol. A smart card communication device determines the valid smart card communication protocol used by a smart card by polling a communication channel using a plurality of smart card communication protocols until a valid acknowledgement message is received. A radio frequency circuit is configured to communicate with the smart card using the valid smart card communication protocol. A digital signal processor having at least two demodulators demodulates an incoming data stream produced by the receiver in accordance with the valid smart card communication protocol m a dynamically reconfigurable manner.
Patent CA-2376974-A1 (CA)
Inventor: SPEER ULRICH
IPC: C09J7/30
Filed: 2000-06-14
Abstract: The invention relates to a simple and economical method for coating an optically readable data carrier, whereby a method and a device for coating said data carrier are disclosed. According to said method, a transparent adhesive film, is deposited upon a surface of the data carrier which is to be protected. A covering film is then placed on top of the adhesive film. An optically readable data carrier with a data-carrying surface which is covered by a transparent film and a covering film is also provided.
Patent CA-2379028-A1 (CA)
Inventor: HAYES FRED JOSEPH
IPC: A61K8/37
Filed: 2000-08-21
Abstract: On décrit des compositions antisudorifiques qui contiennent entre environ 0,1 % et environ 50 % en poids d'un actif antisudorifique solubilisé ( par exemple des matières contenant de l'aluminium ou des matières contenant de l'aluminium et du zirconium) et entre environ 0,1 % et environ 99,9 % en poids d'un polyol liquide contenant au moins deux groupes hydroxyle, le polyol liquide ayant des atomes de carbone adjacents à substitution hydroxy aux positions .alpha. et .beta. du polyol liquide mais pas plus de 4 atomes de carbone adjacents à substitution hydroxy dans le polyol liquide, ledit polyol liquide étant représenté par la formule (I) dans laquelle R représente un amide, ester, alkyle, éther ou silicone et contient au moins trois atomes adjacents sélectionnés dans le groupe formé par le carbone, l'oxygène non hydroxy, l'azote, la silicone et des combinaisons de ces derniers, ledit polyol liquide ayant une valeur ClogP comprise entre environ -4,0 et 2,0. Ces compositions antisudorifiques et les procédés d'application correspondants améliorent l'efficacité, le soin et la douceur des produits antisudorifiques. Ces compositions peuvent également être utilisées en tant que base ou en tant que matières intermédiaires pour formuler d'autres formes de produits antisudorifiques ayant une efficacité similaire. Formule (I)
Patent CA-2379813-A1 (CA)
Title: Nucleic acid sequences encoding polyenoic fatty acid isomerase and uses thereof
Inventor: METZ JAMES GEORGE
IPC: C12N9/90
Filed: 2000-07-28
Abstract: Nucleic acid sequences and methods are provided for producing conjugated fatty acids in host cells. Nucleic acid sequences are obtained from an algal sources which encode polyenoic fatty acid isomerase. The nucleic acid sequences can be used in expression constructs to direct the expression of the PFI sequences in host cells. Expression of PFI in transgenic host cells provides for the production of conjugated fatty acids in the host cell.
Patent CA-2381252-A1 (CA)
Title: 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission
Inventor: DRIZIN IRENE
IPC: A61K31/4439
Filed: 2000-09-14
Abstract: A series of 3-pyrrolidinyloxy-3'-pyridyl ether compounds, a method for selectively controlling neurotransmitter release in mammals using these compounds, and pharmaceutical compositions including these compounds.  Preferred compounds are 3-pyrrolidinylmethoxy-3'-(5'-and/or 6'-substituted) pyridyl ethers.
Patent CA-2382923-A1 (CA)
Inventor: MAY TREVOR
IPC: A47B57/40
Filed: 2002-04-17
Abstract: The locking connector interconnects a shelf supporting beam to an upright of  a knock-down storage rack. The locking connector includes a plunger which is connected to the connector and which is slidable between locking and unlocking positions.  The plunger, when in the locking position, is within one of a number of openings formed i n the upright with resulting locking of the upright to the connector. When the plunger is in the unlocking position, it is outside the opening thus allowing the upright to be separate d from the connector. The first embodiment of the locking connector includes a resilien t rod which is biased into a groove formed in the shank of the plunger when the plunger is in the locking position. The rod prevents the plunger from moving from the locking position  unless a force, opposed to the bias of the rod, is applied to the plunger to cause the rod t o withdraw from the groove. The second embodiment of the locking connector includes a housing which surrounds and protects the plunger. The third embodiment includes a guard fo r protecting the housing when the plunger is in the locking position.
Patent CA-2384476-A1 (CA)
Title: Oximeter sensor with functional liner
Inventor: GORSKI STEPHEN H
IPC: A61B5/00
Filed: 2000-09-08
Abstract: This invention is an improve non-invasive electro-optical sensor probe (10) that is initially L shaped to provide a mechanical means for accurate positioning of the sensor for subsequent use in connection with a patient appendage. The sensor further includes a leveling pad for at least partially surrounding a protruding sensor element (22, 24) to minimize protrusion of the element into the skin of a patient, and a functional liner (18) for use in pretest of the sensor prior to positioning on a patient.
Patent CA-2390387-A1 (CA)
Title: Method of diagnosing rheumatoid arthritis
Inventor: KONISHI YOSHITAKE
IPC: C12Q1/68
Filed: 2000-11-01
Abstract: This invention provides a method for diagnosing rheumatoid arthritis which comprises digesting human genomic DNA with a restriction enzyme EcoRI and detecting an about 7 kb DNA fragment which hybridizes with a probe having the base sequence of the position 159-424 in SEQ ID NO: 1, or which comprises digesting human genomic DNA with a restriction enzyme Dral and detecting an about 1.5 kb DNA fragment which hybrizes with a probe having the base sequence of the position 159-424 in SEQ ID NO: 1. The invention also provides a method for diagnosing rheumatoid arthritis which comprises stimulating the peripheral blood mononuclear cells in a subject with phorbol 12-myristate 13-acetate (PMA) and/or phytohemagglutinin (PHA), and comparing the amount of expression product in the peripheral blood mononuclear cells with the amount of the same product in the peripheral blood mononuclear cells in a healthy person stimulated by PMA and/or PHA, wherein the expression product is expressed from the base sequence of at the least 689-760 position in SEQ ID NO: 1.
Patent CA-2396118-A1 (CA)
Inventor: HASHA RICHARD
IPC: H05B37/02
Filed: 2000-02-03
Abstract: A method system for tracking the state of an entity (e.g., an object) on behalf of a client (e.g., an application program). The states of an entity include up and down. The tracking system of the present invention receives a request from a client to track the state of an entity. The tracking system then watches the state of the entity to detect when the entity enters the up state. When the entity enters the up state, the tracking system performs a behavior that is specified by the client to be performed when the entity enters the up state. When the entity is in the up state, the tracking system monitors the state of the entity to detect when the entity enters the down state. When the entity enters the down state, the tracking system performs a behavior that is specified by the client to be performed when the entity enters the down state. When the tracking system receives a request from the client for a pointer to the entity, the tracking system determines the current state of the entity and either provides a pointer to the entity or indicates that a pointer is not being provided.
Patent CA-2400493-A1 (CA)
Inventor: GRANGER JACQUES
IPC: B65D41/62
Filed: 2000-04-17
Abstract: La capsule (1) comprend une tête et une jupe et est caractérisée en ce qu'el le comprend deux parties assemblées: a) une partie intérieure (3) comprenant un e tête dite intérieure (30) et une jupe dite intérieure (31), typiquement d'ax e de rotation (12), assurant les fonctions dites techniques de ladite capsule,  b) une partie extérieure (4) assurant tout ou partie de la fonction de décoration de ladite capsule (1), de manière à pouvoir modifier à volonté l'aspect de ladite capsule (1) sans avoir à modifier lesdites fonctions techniques.
Patent CA-2401948-A1 (CA)
Inventor: WELCHER ANDREW A
IPC: A61K39/00
Filed: 2001-03-29
Abstract: Novel CD20/IgE-receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing CD20/IgE-receptor like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with CD20/IgE-receptor like polypeptides.
Patent CA-2404006-A1 (CA)
Title: Appareil et procede permettant de mettre a disposition des informations par l'intermediaire l'une interface utilisateur graphique comprenant un ecran tactile
Inventor: PETTERSSON JERRY
IPC: H04N5/91
Filed: 2001-03-23
Abstract: La présente invention concerne un appareil permettant de fournir des informations à un utilisateur. L'appareil comprend : des éléments permettant de fournir des informations visuelles à l'utilisateur, lesdits éléments de mise à disposition d'informations étant conçus pour mettre à disposition des zones actives d'une interface utilisateur fournissant des informations visuelles ; des éléments permettant d'enregistrer un certain nombre d'unités d'informations, chaque unité pouvant être identifiée de façon unique et comprenant des informations d'un premier type, associées à une image visuelle destiné à être mise à disposition par les éléments de mise à disposition d'informations, des informations d'un deuxième type, associées aux zones des éléments de mise à disposition d'informations qui sont actives durant la mise à disposition de l'image visuelle par les éléments de mise à disposition d'informations et, pour chaque zone active, des informations d'un troisième type, associées à l'unité d'information qui doit être mise à disposition sur les éléments de mise à disposition d'informations lorsque la zone active courante est activée ; des premiers éléments servant à identifier les informations de premier type de quelle unité d'informations doivent être mises à disposition sur les éléments de mise à disposition d'informations, les éléments d'identification étant conçus pour agir sur les éléments de mise à disposition d'informations pour qu'ils fournissent les informations de premier type de l'unité d'informations identifiée ; des deuxièmes éléments servant à identifier le moment où une zone active des éléments de mise à disposition d'informations a été activée durant la mise à disposition des informations du premier type d'une unité d'informations courante ; des troisièmes éléments servant à identifier laquelle des zones actives des éléments de mise à disposition d'informations a été activée ; des éléments de modification, se basant sur la zone identifiée par le troisième élément d'identification et les informations de troisième type de l'unité d'informations courante associées à la zone activée identifiée, les éléments de mise à disposition d'informations identifiant ensuite l'unité d'informations associée aux informations du troisième type de l'unité d'informations courante.
Patent CA-2404502-A1 (CA)
Inventor: BROWN JAMES L
IPC: C12Q1/66
Filed: 2001-03-29
Abstract: The present invention provides methods and compositions useful in the diagnosis and management of autoimmune diseases. In particular, the present invention provides an improved detection of thyroid stimulating autoantibodies for the diagnosis and management of Graves' disease. The methods of the present invention create starved cells that result in an improved signal-to-noise ratio following incubation in a salt and glucose solution.
Patent CA-2405168-A1 (CA)
Inventor: HANSEN PAUL E
IPC: A47K10/42
Filed: 2001-04-13
Abstract: L'invention concerne un emballage jetable d'essuie-tout absorbant l'huile se présentant sous forme de plusieurs feuilles discrètes renfermant une bande agglomérée formée par fusion-soufflage de fibres thermoplastiques. La bande présente une valeur d'opacité d'environ 65 au maximum, lorsqu'elle est exempte d'huile, et elle voit sa transparence se modifier d'au moins 30, lorsqu'elle est chargée avec environ 6 grammes d'huile au maximum par centimètre carré. Les essuie-tout sont contenus dans un emballage pourvu d'au moins une ouverture d'accès permettant à un utilisateur de saisir une seule feuille discrète de matière à essuyer.
Patent CA-2405855-A1 (CA)
Inventor: FISCHER SVEN
IPC: H04L27/00
Filed: 2001-04-26
Abstract: Dans les systèmes qui transmettent à la fois des signaux modulés GSM et des signaux modulés EDGE, les estimations de temps d'arrivée peuvent être améliorées sans nécessiter la détection du type de modulation utilisé sur le signal reçu. Selon l'invention, un signal reçu est démodulé initialement par un récepteur en fonction d'un premier schéma de démodulation. Ce signal démodulé est divisé en deux copies. La démodulation initiale étant prise en compte, une des copies est démodulée en fonction d'un autre schéma de démodulation, ce qui permet l'obtention d'un premier signal démodulé en fonction du premier schéma de démodulation et d'un second signal démodulé en fonction d'un second schéma de démodulation. Une séquence d'apprentissage est utilisée pour corréler les deux signaux qui sont ensuite additionnés selon un procédé d'intégration incohérente. Le résultat de l'intégration incohérente est utilisé pour estimer le temps d'arrivée du signal reçu.
Patent CA-2405929-A1 (CA)
Title: Rotor in a rotary electric machine
Inventor: EJIMA HIDEHIRO
IPC: H02K3/487
Filed: 2002-10-01
Abstract: A rotor structure is to be provided which can diminish stress concentration in teeth-wedge fitting portions located near magnetic poles of a rotor in a rotary electric machine. Teeth 6 have slant faces for abutment against slant faces of wedges 8 to retain the wedges in a fitted state between adjacent teeth, the wedges 8 having slant faces each formed at a predetermined angle relative to the radial direction of a rotor 1, and a circular arc is formed at each slant face rising position in the teeth 6. In this case, the radius of the circular arc formed at each slant face rising position 12 in a preset number of teeth 6 located near magnetic pole portions 7 of the rotor 1 is set larger that of the circular arc formed in the remaining teeth.
Patent CA-2408662-A1 (CA)
Title: Silicone removers
Inventor: SERVE WILFRIED
IPC: C11D3/36
Filed: 2001-04-28
Abstract: The present invention relates to the use of a surfactant composition and to the use of cleaning solutions which are obtainable by diluting the surfactant composition for removal of silicone-containing residues from surfaces.
Patent CA-2411660-A1 (CA)
Inventor: TROUET ANDRE
IPC: A61K47/48
Filed: 2001-06-11
Abstract: The prodrug of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by the enzyme Thimet oligopeptidase, or TOP. Also disclosed are methods of designing prodrugs by utilizing TOP-cleavage sequences within the conjugate and methods of treating patients with prodrugs of the invention.
Patent CA-2412378-A1 (CA)
Inventor: MARINZET BERNARD
IPC: F04B9/105
Filed: 2000-06-14
Abstract: The present invention provides a method and an installation for filtering a liquid using a membrane filter device. The technical sector of the invention is the field of manufacturing filter devices, in particular semipermeable membrane devices. In the invention, a pump (3, 4) for pressurizing a liquid has three pistons (24, 25, 26) connected to a common shaft (23) mounted to move in translation in three chambers (18a, 18b; 19a, 19b; 20a, 20b) that are in alignment; two of said pistons (24, 26) being identical and connected to the ends of the shaft (23), each separating one of the chambers (18, 20) into two cavities (18a, 18b, 20a, 20b).