Patent GB-894614-A (GB)
Title: Chemotherapeutic compositions for controlling plant rusts
Inventor: EPPERLY JEAN RAY
IPC: A01N47/24
Filed: 1959-12-23
Abstract: The invention comprises isopropyl 3-(3-chlorophenyl)carbazate, ethyl 3-(3-chlorophenyl)carbazate, ethyl 3 - (3 - nitrophenyl) carbazate, 2 - chloroethyl 3 - (2 - chlorophenyl) carbazate, 4 - chlorophenyl 3 - (4 - bromophenyl) carbazate, ethyl 3 - ethyl - 3 - phenylcarbazate, phenyl 3 - ethyl - 3 - phenylcarbazate, phenyl 3 - (2, 4 - dichlorophenyl) carbazate and 4 - chloro - 2 - butynyl 3-phenylcarbazate.  These are compounds of a general formula <FORM:0894614/IV (b)/1> in which R is alkyl or haloalkyl, alkenyl, alkynyl, aryl (including hydroxy-, halo-, nitro-, alkoxy-, and acyloxy-phenyl) aralkyl, or an alicyclic group; R1 and R2 represent the same or different groups including hydrogen, the groups represented by R above, and groups formed by joining R1 and R2 to form a cyclic secondary amino group in which the nitrogen is part of the ring, including monocyclic and polycyclic groups such as phthalimido, morpholino, pyrrolidino, piperidino, 1, 2, 3, 4 - tetrahydroisoquinolino, 1, 2, 3, - 4-tetrahydroquinolino, isoindolino, 4-methyl-1-piperazino, 3-hydroxypiperidino and 4-hydroxypiperidino, are prepared by reacting the appriate hydrazine of the formula <FORM:0894614/IV (b)/2> with an appropriate ester of chloroformic acid of the formula <FORM:0894614/IV (b)/3> R, R1 and R2 having meanings given above.ALSO:A composition for the control of plant rust which comprises a chemotherapeutic amount of a carbamate having the formula <FORM:0894614/VI/1> wherein R is an alkyl group, particularly a lower alkyl such as methyl, ethyl, propyl, isopropyl, butyl and pentyl, a haloalkyl group; an alkenyl group such as the allyl group; an alkynyl group, an aryl group, particularly a monocyclic group such as naphthyl, phenyl, or a nuclear-substituted phenyl group such as hydroxyphenyl, a halophenyl group such as chlorophenyl, the 3-nitrophenyl group, a lower alkoxyphenyl group such as methoxyphenyl, or a lower acyloxyphenyl group such as the acetoxyphenyl group; an aralkyl group, particularly in which the aryl moiety is monocyclic and the alkyl moiety is a lower alkyl group such as benzyl, phenethyl, or phenylpropyl; or an alicyclic group such as cyclopentyl or cyclohexyl; and R1 and R2 represent the same or different groups including hydrogen, the groups represented by R above, and groups formed by joining R1 and R2 to form a cyclic secondary amino group in which the nitrogen is part of the ring, including monocyclic and polycyclic groups such as phthalimido, morpholino, pyrrolidino, piperidino, 1,2,3,4 - tetrahydroisoquinolino, 1,2,3,4 - tetrahydroquinolino, isoindolino, 4 - methyl - 1 - piperazino, 3 - hydroxypiperidino and 4 - hydroxypiperidino, together with a solid inert carrier, e.g. talc, clay, diatomaceous earth, sawdust, calcium carbonate, and the like, with or without a surface-active agent or liquid inert carrier, e.g. water, kerosene, acetone, benzene, toluene, and the like in which the active agent may be either dissolved or dispersed.  Emulsifying and wetting agents may also be included.  Specified active ingredients are isopropyl 3-(3-chlorophenyl)carbazate, ethyl 3 - (3 - chlorophenyl)carbazate, ethyl 3 - (3 - nitrophenyl)carbazate, 2 - chloroethyl 3 - (2 - chlorophenyl)carbazate, 4 - chlorophenyl 3 - (4 - bromophenyl)carbazate, ethyl 3 - ethyl - 3 - phenylcarbazate, phenyl 3 - ethyl - 3 - phenyl-carbazate, phenyl 3 - (2,4 - dichlorophenyl)-carbazate, 4 - chloro - 2 - butynyl 3 - phenyl carbazate, ethyl 3 - phenylcarbazate, 2 - chloroethyl 3-phenyl carbazate, methyl carbazate.