baber/WOPTO huggingface dataset:
Patent EP-3838731-A2 (EP)
Title: Fahrrad-schaltwerk und anbindung eines schaltwerks an einem fahrrad-rahmen
Inventor: BRAEDT HENRIK
IPC: B62M9/125
Filed: 2020-12-10
Abstract: Es werden verschiedene Lösungen zur Anbindung eines Fahrrad-Schaltwerks an das Rahmenauge oder Ausfallende eines Fahrradrahmens vorgeschlagen. Gemäß einem ersten Aspekt der Erfindung kommt ein Halterungselement mit einem Halterungsbolzen zum Einsatz. Das Halterungselement ist mit einer Einführhülse ausgeführt. Erfindungsgemäß ist vorgesehen, dass wenigstens ein Element von der Einführhülse (20) und dem Halterungsbolzen (22) mit wenigstens einer Eingriffsformation (34) ausgeführt ist, welche dafür eingerichtet ist, zusammen mit wenigstens einem gegenüber der Einführhülse und dem Halterungsbolzen gesonderten Gegeneingriffselement (32) oder einer Gegeneingriffsformation (52) des jeweils anderen Element von der Einführhülse und dem Halterungsbolzen eine elastische Einschnapp-Halteverbindung oder eine bajonettartige Halteverriegelung herzustellen, die einen formschlüssigen Halteeingriff zwischen der Einführhülse (20) und dem Halterungsbolzen (22) realisiert.
Patent EP-3698631-A2 (EP)
Inventor: NOVOBRANTSEVA TATIANA
IPC: A61P37/02
Filed: 2010-05-05
Abstract: The invention relates to the field of delivery of nucleic acid-based agents to immune cells.
Patent EP-3691238-A2 (EP)
Inventor: MIKASHIMA KATSUO
IPC: G06T3/40
Filed: 2020-02-02
Abstract: An image forming apparatus (100) includes a conveyance part (5), an image forming part (9), a sheet detection sensor (60), a sensor unit (51), and a controller (74). The sheet detection sensor (60), in which a plurality of sensor blocks (60b) each with a plurality of sensor elements (60a) mounted thereon at specified intervals are arrayed in a sheet width direction, detects an edge position in the sheet width direction on a basis of scanning image data formed by reading of the sheet. The controller (74) is enabled to execute a calibration of inserting, into the scanning image data, interpolation pixels (Ip) for compensating an error between an edge position detected by the scanning image data and an actual edge position.
Patent EP-3839053-A2 (EP)
Inventor: MUNDHADA HEMANSHU
IPC: C12N15/00
Filed: 2016-01-27
Abstract: The present invention generally relates to the microbiological industry, and specifically to the production of L-serine or L-serine derivatives using genetically modified bacteria. The present invention provides genetically modified microorganisms, such as bacteria, wherein the expression of genes encoding for enzymes involved in the degradation of L-serine is attenuated, such as by inactivation, which makes them particularly suitable for the production of L-serine at higher yield. The present invention also provides means by which the microorganism, and more particularly a bacterium, can be made tolerant towards higher concentrations of serine. The present invention also provides methods for the production of L-serine or L-serine derivative using such genetically modified microorganisms.
Patent EP-3947418-A2 (EP)
Inventor: WARENIUS HILMAR M
IPC: C07K7/64
Filed: 2020-03-25
Abstract: The present invention relates to a cyclic peptide comprising an active region comprising the amino acid sequence X 1 X 2 X 3 X 4 X 5 X 6  or a salt, derivative, prodrug or mimetic thereof. X 2  and X 5  are arginine; and either: X 1  is (7-methoxy-coumarin-4-yl)-Ala-OH (Dac) and X 3 , X 4  and X 6  are any amino acid; or X 3  is sarcosine (Sar) and X 1 , X 4  and X 6  are any amino acid; or X 4  is 5,5-dimethylproline (dm Pro) or 3-amino-3-(2-naphthyl)propionic acid (Nap) and X 1 , X 3  and X 6  are any amino acid; or X 6  is Nap and X 1 , X 3  and X 4  are any amino acid. The present invention further relates to a pharmaceutical composition comprising the cyclic peptide and the peptide for use in medicine, and particularly cancer.
Patent EP-4171264-A2 (EP)
Inventor: TANU UR SAMANCI ASLI ELIF
IPC: A23L29/206
Filed: 2020-12-12
Abstract: The invention relates to a method for production of honey powder and comprises process steps of mixture of at least an auxiliary encapsulation agent selected from a group consisting of water soluble gum, maltodextrin, starch, gelatine, sodium caseinate pectin or mixture of them, measuring viscosity of mixture, adding Distilled water to mixture until viscosity value of 15-20 mPa.s is achieved, applying homogenization process, bringing temperature of mixture to 45°C, obtaining honey powder by drying at spray drier.
Patent EP-3926586-A2 (EP)
Inventor: LABBE HUGUES
IPC: H04N19/597
Filed: 2018-03-29
Abstract: Systems, apparatuses and methods may provide for technology that partitions a three-dimensional (3D) scene into a plurality of layers including at least a foreground layer and a background layer. Additionally, the foreground layer may be rendered at a first rate and the background layer may be rendered at a second frame rate, wherein the first frame rate is greater than the second frame rate. In one example, the foreground layer and the background layer are composited into a frame.
Patent EP-3961960-A2 (EP)
Inventor: HUANG CHUN-WEI
IPC: H04B7/0408
Filed: 2021-08-20
Abstract: A User Equipment, UE, monitors a first Physical Downlink Control Channel, PDCCH, via a first spatial Quasi-Colocation, QCL, assumption associated with a first Transmission Configuration Indicator, TCI, state, on a first monitoring occasion of a first Control Resource Set, CORESET, (1805). 
     Then, the UE monitors a second PDCCH, via a second spatial QCL assumption associated with a second TCI state, on a second monitoring occasion of a second CORESET (1810). 
     Both the first PDCCH and the second PDCCH schedule a Physical Downlink Shared Channel, PDSCH. 
     The UE determines an interval between the most recent monitoring occasion and the PDSCH (1815). If the interval is larger than or equal to a threshold, which is generally determined via the field timeDurationForQCL, the UE receives the scheduled PDSCH via a third spatial QCL assumption associated with a third TCI state, wherein the third TCI state is the TCI state of the PDCCH received on the monitoring occasion of the CORESET having the lowest CORESET identity, CORESET ID, between the CORESET ID of the first CORESET and the CORESET ID of the second CORESET (1820).
Patent EP-3998459-A2 (EP)
Inventor: SUBRAMANIYAN MUTHUSANKAR
IPC: H04W4/02
Filed: 2021-10-20
Abstract: Disclosed are methods, systems, and non-transitory computer-readable media for generating visual cues for spatial communication coverage. For instance, the method may include obtaining a proposed travel path for a vehicle; locating one or more communication channels accessible to an operator of the vehicle in an area that includes at least a portion of the proposed travel path; and analyzing one or more characteristics of the one or more communication channels to determine one or more positions within the area at which the one or more communication channels will be inaccessible to the operator. The method may further include calculating a present position and a velocity of the vehicle; determining communication channel availability; and presenting the communication channel availability to the operator via a graphical user interface.
Patent EP-4088554-A2 (EP)
Title: Buses de chalumeau de coupe à arc de plasma refroidi par liquide avec passages indépendants de la synchronisation
Inventor: CHEVALIER ADAM
IPC: H05H1/28
Filed: 2021-01-08
Abstract: La présente invention concerne une buse d'un chalumeau de coupe à arc de plasma refroidi par liquide. La buse comprend un corps de buse creux et une chemise de buse disposée autour d'une surface externe du corps de buse. La chemise délimite (i) une longueur le long de l'axe longitudinal central et (ii) un diamètre d'une pointe distale de la chemise au niveau de la région distale de la buse, la longueur étant supérieure à environ 1,5 pouce et un rapport de la longueur au diamètre étant supérieur à environ 1,4. La buse comprend également une entrée de liquide de refroidissement et une sortie de liquide de refroidissement délimitées entre le corps de buse et la chemise de buse au niveau de la région proximale de la buse. La buse comprend en outre une pluralité de canaux de fluide de refroidissement délimités par coopération entre le corps de buse et la chemise de buse. Les canaux de la pluralité de canaux de refroidissement s'étendent axialement entre la région proximale et la région distale de la buse.
Patent EP-4133293-A2 (EP)
Inventor: HSIEH ANDREW G
IPC: G01R31/36
Filed: 2021-01-08
Abstract: Systems and methods for acoustic signal based analysis, include obtaining acoustic response signal data of at least a portion of a battery cell, the acoustic response signal data comprising waveforms generated by transmitting one or more acoustic excitation signals into at least the portion of the battery cell and recording response vibration signals to the one or more acoustic excitation signals. One or more metrics are determined from at least the acoustic response signal data, the one or more metrics being determined based on correlation of the one or more metrics to one or more characteristics of battery cells and a reference model is generated from the one or more metrics. A test battery can be evaluated using the reference model. Actionable insights or recommendations can be generated based on the evaluation. The reference model can also be updated based on the evaluation.
Patent EP-4153619-A2 (EP)
Inventor: DUDKIN VADIM
IPC: C07K16/30
Filed: 2021-05-19
Abstract: Engineered antibodies useful for site-specific conjugation by a transglutaminase are described. Also described are methods of site-specific conjugation of the antibodies, the site-specifically conjugated antibodies, and pharmaceutical compositions and uses related to the site-specifically conjugated antibodies.
Patent EP-4172201-A2 (EP)
Inventor: BERNDT SANDRA
IPC: C07K16/24
Filed: 2021-06-25
Abstract: The present invention relates to tools and methods for the generation of antibodies which specifically bind chemokine receptors, such as CC or CXC chemokine receptors. Provided are isolated sulfated polypeptides and conjugates thereof, which can be used for example as antigens or for off target panning to facilitate the generation of anti-human, anti-cynomolgus, and/or anti-mouse chemokine receptor antibodies, e.g. for the generation of antibodies with fully human CDRs and/or other favorable properties for therapeutic use. The present invention furthermore relates to antibodies and conjugates thereof which can be obtained by applying the aforementioned tools and methods. Provided are antibodies specifically binding to human, cynomolgus and/or murine CCR8 with favorable properties for therapeutic use, such as cross-reactive antibodies, fully human antibodies, low internalizing (including non-internalizing) antibodies, and antibodies efficiently inducing ADCC and/or ADCP in Treg cells. Also provided are medical uses of the inventive antibodies or conjugates and/or treatment methods comprising the administration of these antibodies to a patient or subject, either alone or in combination. Biomarkers, stratification methods and diagnostic methods are finally provided to predict or evaluate responsiveness to anti-CCR8 antibody monotherapy or combination therapy. The invention furthermore provides tools and methods for producing the foregoing antibodies, pharmaceutical compositions, diagnostic uses of the antibodies, and kits with instructions for use.
Patent EP-4168287-A2 (EP)
Title: Carrier frame
Inventor: YUAN JIALIANG
IPC: B62B9/20
Filed: 2021-07-02
Abstract: The present invention discloses a carrier frame (100) including a first tubular member (1), a second tubular member (2), a third tubular member (3) and a folding unit (4) including a first rod (42), a linkage rod (43), a second rod (44) and a pivot frame (41) pivoted to the second tubular member (2). The first rod (42) is pivoted to the pivot frame (41) at a first pivot point and a second pivot point respectively. The linkage rod (43) is pivoted to the first tubular member (1) and pivoted to the pivot frame (41) at a third pivot point. The second rod (44) is pivoted to the third tubular member (3) and pivoted to the linkage rod (43) at a fourth pivot point. The second, third and fourth pivot points are located at the same pivot axis. The carrier frame (100) can be released and folded synchronously and has advantages that the carrier frame (100) is easy to fold, has a simple structure, and is convenient to operate.
Patent EP-4099968-A2 (EP)
Inventor: WIEMER MICHAEL WEST
IPC: G02C7/04
Filed: 2021-03-22
Abstract: An electronic intraocular device is implantable into the capsular bag of a wearer's eye. In some cases, the intraocular device may include a femtoprojector. The femtoprojector projects images onto the wearer's retina when the electronic intraocular device is implanted in the wearer's eye. Different haptic designs may be used to keep the femtoprojector in position. In some embodiments, an imager is contained in a contact lens worn by the wearer. Images captured by the contact lens imager may be relayed to the intraocular femtoprojector. In some cases, the intraocular device may include an electronic capsular tension ring with a femtoimager. The femtoimager may capture images of the wearer's retina, for example for purposes of monitoring eye health.
Patent EP-4225392-A2 (EP)
Inventor: HAECKER JUERGEN
IPC: A61M1/16
Filed: 2021-10-06
Abstract: Die vorliegende Erfindung betrifft einen Port (100) zum Herstellen einer Fluidverbindung zwischen wenigstens einer dem Inneren (I) einer Behandlungsvorrichtung (2000) zugeordneten Fluidleitung (2002) der Behandlungsvorrichtung (2000) und einem Konnektor (4001) einer dem Äußeren (Ä) der Behandlungsvorrichtung (2000) zugeordneten Fluidleitung (4002) eines fluidführenden Disposable (4000), wobei der Port (100) wenigstens eine erste Fluidführung (3) und eine zweite Fluidführung (5) aufweist. Die erste Fluidführung (3) hat wenigstens ein erstes Lumen (31) und eine erste endseitige Öffnung (32), welche zur Aufnahme und/oder Führung eines ersten, medizinischen Fluids und zum Herstellen der Fluidverbindung mit dem Konnektor (4001) vorgesehen sind. Die zweite Fluidführung (5) hat wenigstens ein zweites Lumen (51) und eine zweite endseitigen Öffnung (52). Die erste endseitige Öffnung (32) der ersten Fluidführung (3) ist, zumindest abschnittsweise, im zweiten Lumen (51) der zweiten Fluidführung (5) angeordnet. Es werden ferner eine medizintechnische Behandlungsvorrichtung und ein System vorgeschlagen.
Patent EP-4200287-A2 (EP)
Inventor: BOOTH RAYMOND
IPC: C07D307/94
Filed: 2021-08-19
Abstract: Compounds, compositions, and methods are provided for dual partial agonism of serotonin 5-HT 7  and 5-HT 1A  receptors. The enantiomerically pure 5- p henyl-2-amino t etralin (5-PAT) compounds can be used to treat or prevent substance use disorder, opioid use disorder, addiction, anxiety, psychosis, depression, autism spectrum disorder, fragile X syndrome, neurological disorders, neuropsychiatric disorders, repetitive behaviors, movement disorders, compulsions, tics, pain disorders, vasospastic disorders, migraine headache, seizures, epilepsy, social anxiety, addiction withdrawal, drug withdrawal, drug abuse, alcoholism, eating disorders, general inflammation disorders, miosis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, and gastrointestinal disorders.
Patent EP-4135340-A2 (EP)
Inventor: ZHU YONG
IPC: H04R1/34
Filed: 2022-03-29
Abstract: A sound-producing structure includes: a hollow piece (131); a sound-producing piece located in a hollow cavity (130) of the hollow piece (131); and a heat dissipation piece (150) located outside the hollow cavity (130), a first part of the heat dissipation piece (150) being located below the hollow piece (131) and a second part of the heat dissipation piece (150) being on a side wall of the hollow piece (131).
Patent EP-4101308-A2 (EP)
Inventor: MOLLO MARCO
IPC: A23P20/20
Filed: 2022-05-27
Abstract: Described herein is a system for depositing foodstuff material in the fluid state on a foodstuff product, comprising:- a conveying line (2) for feeding a plurality of foodstuff products (100) in a direction of advance (K);- at least one unit (10) for dispensing the foodstuff material on the foodstuff products (100) that advance on the conveying line (2), where the dispensing unit (10) comprises a plurality of rows of nozzles (11) arranged in a direction transverse to the direction of advance (K); and- a control unit (6) for controlling the dispensing unit (10),wherein said dispensing unit (10) comprises a valve device (20) associated to each individual nozzle (11') and designed to control the flow of the foodstuff material through the nozzle (11'),the valve device (20) comprising:- an open/close member (21);- a solenoid (24); and- a magnetic element (25) operatively connected to the open/close member (21) and mobile between a first position in which it closes the respective nozzle (11'), preventing dispensing of the foodstuff material therethrough, and a second position in which a passage is opened through the nozzle (11') for dispensing the foodstuff material.
Patent EP-4183806-A2 (EP)
Inventor: DA SILVA ANA PAULA GALVAO
IPC: C07K16/44
Filed: 2015-11-12
Abstract: The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include monoclonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them. Further provided are methods of using glycan-interacting antibodies to target cells and treat disease.
Patent EP-4301420-A2 (EP)
Inventor: DE CASTRO GONÇALVES DE ALMADA LOBO INÊS
IPC: A61L2/08
Filed: 2022-03-01
Abstract: La présente invention concerne un système de stérilisation activé par la lumière intégré réutilisable, ainsi qu'un procédé de préparation du système de stérilisation. De plus, la présente invention concerne un capuchon de cathéter comprenant le système de stérilisation activé par la lumière réutilisable.
Patent EP-4268119-A2 (EP)
Title: Smart port - multifunktionales lese/erkennungsgerät im sterilgutkreislauf
Inventor: LENZENHUBER FREDERICK
IPC: G06K7/00
Filed: 2022-08-02
Abstract: Die vorliegende Offenbarung betrifft einen Smart Port (1) zum Erfassen und Auslesen von medizinischen Produkten (2) mittels einer Vielzahl an, vorzugsweise modularen Modulen, welche jeweils mit unterschiedlichen Erfassungstechnologien vorgesehen und ausgebildet sind. Ferner betrifft die vorliegende Offenbarung ein System (17) mit einem Smart Port (1), einem Siebkorb (18) und darin einbringbaren Instrumentenhaltern (19), welcher die medizinischen Produkte (2) halten. Ferner betrifft die vorliegende Offenbarung einen Roboterarm (21 ) mit einem daran angebrachten oder darin integrierten Smart Port (1) sowie eine Vorrichtung mit einer künstlichen Intelligenz zum Erkennen und Beurteilen von medizinischen Produkten.
Patent EP-4223467-A2 (EP)
Inventor: BUCKS BRENT
IPC: B26D7/06
Filed: 2017-10-02
Abstract: Cutting head (100) for a centrifugal cutting apparatus, comprising cutting stations (101, 201, 301), each of which has a cutting element (105, 205, 305) at a leading end (104, 204, 304) and an inner wall extending from the leading end to a trailing end (107, 207, 307) and forming a product sliding surface (110, 210). The cutting stations (101, 201, 301) are assembled adjacent one another with a gap (109) between each pair of adjacent cutting stations, a rake-off angle θ R  being defined as the angle that a product slice deviates upon being cut by one of the cutting elements and exiting the cutting head through the respective gap, said angle being measured relative to a tangent line to the product sliding surface at the trailing end of the respective preceding cutting element. Each cutting station has a concave inner wall (110, 210) with a first part (108) having a first wall curvature R1 -1 , wherein a rear part (108'; 108") of the product sliding surface at the trailing end has a second, different wall curvature R2 -1  with respect to said first wall curvature R1 -1  to change the rake-off angle θ R .
Patent EP-4235777-A2 (EP)
Inventor: CHEN WEI
IPC: H01L25/065
Filed: 2021-02-10
Abstract: Multiple chip module (MCM) structures are described. In an embodiment, a module includes a first and second components on the top side of a module substrate, a stiffener structure mounted on the top side of the module substrate, and a lid mounted on the stiffener structure and covering the first component and the second component. The stiffener is joined to the lid within a trench formed in a roof of the lid.
Patent EP-4272738-A2 (EP)
Title: Anti-cd38 antibodies for treatment of acute lymphoblastic leukemia
Inventor: DOSHI PARUL
IPC: A61K31/475
Filed: 2015-02-25
Abstract: The present invention relates to combination therapies with anti-CD38 antibodies.
Patent EP-4302708-A2 (EP)
Title: Systems and methods for endoscopic submucosal dissection using magnetically attachable hemoclips
Inventor: DOBASHI AKIRA
IPC: A61B17/04
Filed: 2018-11-08
Abstract: A device for use in gastro-intestinal surgery comprising a set of two or more magnet-attached clips, each magnet-attached clip including a clip having a pair of jaws configured to move between open and closed configurations, a suture having a first end secured to one of the jaws, and a magnet attached to a second end of the suture.
Patent EP-4302791-A2 (EP)
Title: Systems and methods for improving control responsiveness during aspiration
Inventor: MERKEL BRETT R
IPC: A61M1/00
Filed: 2019-09-24
Abstract: An aspiration system to control vacuum pressure in an ultrasonic surgical handpiece to result in improved control responsiveness during aspiration is described. The system comprises a console comprising a vacuum pump, a surgical waste receiver, a clean side flow path, the clean side flow path positioned between the vacuum pump and the surgical waste receiver, a dirty side flow path, a fluid backflow device in communication with the dirty side flow path, a clean side venting mechanism in communication with the clean side flow path, and a second venting mechanism in communication with the fluid backflow device, wherein the dirty side flow path is positioned between the ultrasonic surgical handpiece and the fluid backflow device.
Patent EP-0005282-A2 (EP)
Inventor: STRIFFELER WERNER
IPC: H01B7/295
Filed: 1979-03-27
Abstract: Die Vergußmasse besteht im wesentlichen aus einem chlorierten aliphatischen oder aromatischen flüssigen Kohlenwasserstoff mit bei Raumtemperatur geringer Viskosität, einem in kleiner Menge im chlorierten Kohlenwasserstoff gelösten, als HCl-Akzeptor wirkenden, gegenüber aliphatischen Aminen inerten, cycloaliphatischen Epoxidharz, einem im chlorierten Kohlenwasserstoff löslichen niedermolekularen, brombegrenzten Polybutadien mit einer Viskosität von etwa 2 · 10<5> mPas bei Raumtemperatur, einem die Vernetzung bei Raumtemperatur ermöglichenden aliphatischen Polyamin oder Polyaminoamid und einer kleinen Menge Antimontrioxid. Ferner enthält die Masse einen mineralischen Füllstoff, Farbpigmente, Alterungsschutzmittel sowie bis zu 50 Volumenprozent eines gasförmigen Stoffes in feinverteiltem Zustand. Die Vergußmasse eignet sich vor allem zum Ausfüllen von Hohlräumen in elektrischen Apparaten, weist gute elektrische Durchschlagfestigkeit und einen niedrigen dielektrischen Verlustfaktor tgδ auf und ist selbstlöschend sowie kompressibel.