baber/WOPTO huggingface dataset:
Patent DE-69634907-T2 (DE)
Inventor: OOMURA YUTAKA
IPC: A61K38/00
Filed: 1996-04-25
Granted: 2006-05-18
Abstract: An object of the present invention is to offer a peptide fragment which is useful as a pharmaceutical agent, etc. In the peptide fragment of the present invention, a 1-29 amino acid residue peptide fragment of aFGF in which cysteine, an amino acid at 16-position, was substituted with another amino acid. In the passive avoidance learning test and the maze-learning test in water, the peptide of the present invention was confirmed to exhibit an excellent action of improving the learning and the remembering of the senility-accelerated mice in which remembering and learning abilities were reduced. The peptide fragments have also the protecting effects against the death of cerebral neurons caused by ischemia. As such, the substance of the present invention shows excellent improving actions to brain functions and protecting cerebral neurons. Accordingly, said substance is useful as a pharmaceutical agent against dementia and other diseases caused by reduction of various brain functions.
Patent DE-69702135-T2 (DE)
Inventor: DEVAUX FRANCOIS
IPC: G06F1/00
Filed: 1997-07-22
Granted: 2000-11-09
Abstract: A system for securely storing CD-ROM data including a CD-ROM having data encrypted at least in part with a cryptographic algorithm having a decryption key K, a CD-ROM drive for receiving the CD-ROM, an electronic decryption microcircuit embedded in the CD-ROM, means for exchanging information between the CD-ROM drive and the electronic decryption microcircuit embedded in the CD-ROM, and a chip card containing at least a part K1 of the decryption key K, any remaining part K2 of the decryption key K being in the electronic decryption microcircuit embedded in the CD-ROM. Also included is a secure means for securely exchanging information between the chip card and the electronic microcircuit embedded in the CD-ROM. Further, the electronic decryption microcircuit embedded in the CD-ROM includes an antenna which provides, without the presence of contact, both an electrical power supply to the decryption microcircuit from an external source and exchanges of information with the external source.
Patent DE-69702664-T2 (DE)
Inventor: JENTJENS GREGORIUS ANDRE CHRIS
IPC: B65G47/64
Filed: 1997-09-03
Granted: 2001-03-29
Abstract: PCT No. PCT/NL97/00506 Sec. 371 Date May 26, 1999 Sec. 102(e) Date May 26, 1999 PCT Filed Sep. 3, 1997 PCT Pub. No. WO98/09894 PCT Pub. Date May 12, 1998A conveyor for transporting objects. The vertically adjustable end of the first conveyor is positioned near the vertically adjustable ends of at least two further conveyors positioned one above the other. In a first position, the end of the first conveyor joins the end of one of the further conveyors. In a second position, the end of the first conveyor joins the end of the other of the further conveyors. The vertically adjustable ends of the conveyors are interconnected by means of a flexible connecting element including two parts extending from a guide mechanism in the direction of the ends of the conveyors. One part is connected to the first conveyor and the other part is connected to the further conveyors.
Patent DE-69704944-T2 (DE)
Inventor: SALA GIAMPAOLO
IPC: G07F7/00
Filed: 1997-06-09
Granted: 2001-12-20
Abstract: A container for a system to collect, manage, process and move photographic material, contained in wrappers of a defined form, for example rolls (24) is associated with an automatic device to collect the photographic material to be processed and also with at least a processing machine (13, 14) including its own data processing unit (41). The automatic collection device includes means to recognize the client (28), means (29) to input commands and aperture means (23) for the introduction of the roll (24). The container (30) includes a plurality of individually accessible locations to position the rolls (24) in an orderly manner and memorization means (12) solid with the container, the memorization means (12) being able to be functionally associated with the means to recognize the client (28) for the univocal identification of the specific roll (24) and with the data processing unit (41) of the processing machine (13, 14) to transfer the univocal identification of the specific roll (24), and the container (30) including closure means (43, 143) and cooperating with moving means (35, 46, 74), the container (30) cooperating with devices (65, 165) for the automatic extraction of the rolls (24).
Patent DE-69705055-T2 (DE)
Inventor: BRUNERIE MARC
IPC: A61K8/00
Filed: 1997-07-15
Granted: 2001-11-08
Abstract: Compounds with a 1,3-dioxane structure of general formula (I), wherein Z is pentyl or pent-2-enyl grouping (Z) or (E) and R is a hydrocarbon grouping, characterised in that they are prepared from apples or apple by-products, are disclosed. A method for synthesising said compounds by acetylising the corresponding 1,3-diol of general formula (II), wherein Z is as defined above, with an aldehyde of formula (a), wherein R is as defined above, is also disclosed. Furthermore, aromatic compositions containing the compounds with a 1,3-dioxane structure prepared according to said synthesis method, are disclosed.
Patent DE-69705275-T2 (DE)
Inventor: UEDA YASUYOSHI
IPC: C07C231/02
Filed: 1997-03-06
Granted: 2002-05-16
Abstract: A process for preparing N< omega >-trifluoroacetyl-basic amino acid from a basic amino acid and a trifluoroacetic ester which comprises: adding successively a trifluoroacetic ester to a basic aqueous liquid containing a basic amino acid and a basic pH adjusting agent at a concentration at which a total weight of the basic amino acid is about 5 to 40 % (w/v) relative to the volume of a charged solvent while maintaining the pH of the aqueous liquid in a range of 10.6 to 11.4 and the temperature at 20 DEG C or lower, thereby performing the reaction, and crystallizing and collecting N< omega >-trifluoroacetyl-basic amino acid from the aqueous liquid after the reaction.
Patent DE-69709079-T2 (DE)
Inventor: SCOCCO ROBERTO
IPC: G07F13/02
Filed: 1997-07-17
Granted: 2002-05-02
Abstract: The self-service device provides the distribution of the product from the original container (1) by means of a level sensor consisting of a photoelectric cell (6) connected on line (7) with a computer (8) also connected with a keyboard (10) and with an electronic valve (12). To draw the product, the customer digits the quantity of product to buy on the keyboard (10) so causing the going out of the same through the electronic valve (12) and its discharge, through an output device, into a carry-way container (17) placed in station (18). Said output device provides on a fixed frame (19) an air cylindr (20) controlled by an electronic valve for the vertical translation of the mobile part of the frame with two pipes with a 90 DEG  angle of which the horizontal pipe (23) gets into the other vertical pipe (25) with a larger diameter stabilized in a coaxial guide (26) of the fixed frame and providing a servomotor (27) to translate inside itself an axial pipe (28). When in non-delivery condition, the axial pipe (28) obstructs with its lower blocking end (31) with hole (35) the delivery mouth (33) sets between the inside wall (30) of the coaxial pipe (25) and the outside wall (34) of the axial pipe (28). On receiving of the delivering order of the product (13), the electronic valve (22) actuates the coming of the mobile part of the frame (23-25) to the lower limit stop with introduction into the container (17) of the lower tract (40) of the pipe (25) with blocking end (31) and conic gasket (42). The computer (8) then starts the servomotor (27) bringing in downward sliding the axial pipe (28) so opening, through the lowering of the blocking end (31), the delivery mouth (33) so that the product (13), through the horizontal duct (45) and vertical duct (46), comes out to the mouth (33) to fill up the container (17). <IMAGE>
Patent DE-69709658-T2 (DE)
Inventor: MATSUZAWA KENJI
IPC: B01J27/053
Filed: 1997-09-03
Granted: 2002-08-14
Abstract: A molded solid acid catalyst which is used in an isomerization reaction of hydrocarbons and the like, has high activity and excellent strength, and is easy to handle, and a process of preparing the same. This catalyst comprises a carrier comprising tetragonal zirconia and alumina and, supported thereon, a sulfuric acid component and optionally a group 8-10 metal component, wherein the specific surface area of the catalyst is not less than 150 m<2>/g. The catalyst can be prepared by kneading an aluminum hydroxide, a zirconium hydroxide and a compound containing a sulfuric acid component together, molding the mixture, firing the molding at a temperature capable of providing a tetragonal zirconia, and optionally further supporting a group 8-10 metal component and conducting firing at 300 to 700  DEG C.
Patent DE-69710770-T2 (DE)
Inventor: CATTABRIGA MATTEO
IPC: B41J15/16
Filed: 1997-10-14
Granted: 2002-07-18
Abstract: The device for stabilising the tension of a paper ribbon (2) is arranged in an ink-jet, vertical plotter, for tracing shapes for cloths. Said plotter is provided with a paper dragging system (1) comprising: a feeding roller (10), supporting a feeding web (3); a supporting and dragging roller (11), supporting said ribbon (2) near a printing head (4), and dragging said ribbon (2); a rewind roller (13), receiving said ribbon (2). The aforesaid device consists of oscillating tensioning means (30), which operates on the upper face (2a) of said ribbon (2), and which exerts on this latter a substantially constant force, against the dragging force exerted by the supporting and dragging roller (11).
Patent DE-69713514-T2 (DE)
Inventor: HINDSGAUL OLE
IPC: C07H3/04
Filed: 1997-11-07
Granted: 2003-01-09
Abstract: Disclosed are novel solid support matrices having a toxin-binding oligosaccharide covalently attached to a solid support through a linking arm which has at least 8 atoms separating the oligosaccharide from the solid support. The disclosed solid support matrices are useful for neutralizing toxins from disease-causing microrganisms.
Patent DE-69717619-T2 (DE)
Inventor: LAURSEN FIN G
IPC: E02D17/18
Filed: 1997-05-07
Granted: 2003-09-18
Abstract: In the construction of a steep embankment a planar front grid (2) is used, said grid being positioned with a given inclination corresponding to the completed embankment, immediately adjacent the front of the completed embankment. At a point in the earth formation behind the completed embankment an anchor element (5) is placed, and between the front grid (2) and the anchor element (5) one or more fixed anchors (4a, 4b) are established to secure the front grid (2) in relation to the anchor element (5). Furthermore, one or more layers of geo-net (7) are preferably placed or inserted below or above the anchor element (5) and behind the front grid (2). Finally, the area behind the front grid (2) is filled up, whereby the anchor element (5) is covered to provide the earth formation in the completed embankment. In this method is used a universally applicable system comprising a planar front grid, an anchor element and a number of anchor braces or struts, said system being immediately adaptable to a given application. <IMAGE>
Patent DE-69723085-T2 (DE)
Inventor: JOHNSON D
IPC: B21D51/26
Filed: 1997-07-17
Granted: 2004-05-06
Abstract: A can body embossing apparatus has a first mandrel with a first tooling member adapted to receive thereon a can body and a second mandrel with a second tooling member reciprocally movable from a first position distal the first tooling member to a second position proximate the first tooling member. In the second position, the can body side wall is engaged between the first tooling member and the second tooling member. The first tooling member defines one or more recessed portions therein and the second tooling member defines one or more protuberances extending therefrom and adapted to correspond with the recessed portions. The first mandrel and second mandrel are in mechanical communication throughout the reciprocal movement of the second mandrel such that the first and second tooling members rotate continuously with respect to each other and maintain a substantially constant relative position with respect to each other. The continuous side wall of the can body is conveyed between the first and second tooling members to effect the embossing of the side wall resulting in the formation of decorative embossed features in the side wall.
Patent DE-69729348-T2 (DE)
Inventor: SAVAGE STUART
IPC: B60S3/00
Filed: 1997-06-25
Granted: 2005-06-16
Abstract: An apparatus suitable for monitoring the efficiency of vehicle cleaning equipment, said apparatus comprising a test panel adapted to be temporarily secured to the exterior of a vehicle whilst it passes through the cleaning equipment, the face of the test panel which is exposed to the cleaning process being pre-coated with a known dirt loading, the surface of the test panel being adapted for non-destructive physical evaluation to determine the proportion of pre-coated dirt which has been removed during the cleaning process. <IMAGE>
Patent DE-69733020-T2 (DE)
Inventor: CARSON A
IPC: A61K47/48
Filed: 1997-10-09
Granted: 2006-02-16
Abstract: Immunostimulatory polynucleotide-immunomodulatory molecule conjugate compositions are disclosed. These compositions include a polynucleotide that is linked to an immunomodulatory molecule, which molecule comprises an antigen and may further comprise immunomodulators such as cytokines and adjuvants. The polynucleotide potion of the conjugate includes at least one immunostimulatory oligonucleotide sequence (ISS). Methods of modulating an immune response upon administration of the polynucleotide-immunomodulatory conjugate preparation to a vertebrate host are also disclose.
Patent DE-69736331-T2 (DE)
Inventor: KRIEG ARTHUR M
IPC: C12N15/117
Filed: 1997-10-30
Granted: 2007-08-09
Abstract: An isolated immunostimulatory oligonucleotide comprising two or more unmethylated CpG dinucleotides, and having a sequence including the following formula:  
5'N 1 X 1 X 2 CGTTN 2 3'  
wherein the immunostimulatory oligonucleotide includes a modified backbone, at least one nucleotide separates consecutive CpGs, X 1 X 2  is GpT or ApT, N 1  is any nucleotide that includes a 5' TC or TG, N 1  + N 2  is from 0-26 bases, and the immunostimulatory oligonucleotide is from 8-30 bases in length and begins with TC or TG at the 5' end, with the proviso that neither N 1  nor N 2  contains a CCGG quadmer or more than one CCG or CGG trimer.
Patent DE-69805267-T2 (DE)
Inventor: HAYASHI TAKETO
IPC: C07D473/32
Filed: 1998-11-10
Granted: 2002-10-02
Abstract: A purine derivative having a cyclopropane ring represented by the formula (I): <CHEM> wherein A is -CH2- group or -CO- group; X<1> is hydrogen atom, a halogen atom, an alkoxy group having 1 to 10 carbon atoms, or hydroxyl group; each of X<2>, X<3>, and X<4> is independently hydrogen atom or a halogen atom; R<1> is hydrogen atom, a halogen atom, or a protected or unprotected amino group; and each of R<2> and R<3> is independently hydrogen atom, a substituted or unsubstituted alkyl group having 1 to 7 carbon atoms, a substituted or unsubstituted aralkyl group having 7 to 11 carbon atoms, or a substituted or unsubstituted acyl group having 1 to 7 carbon atoms, with proviso that in a case where A is -CO- group, neither R<2> nor R<3> is a substituted or unsubstituted acyl group having 1 to 7 carbon atoms, and each of X<3> and X<4> is independently a halogen atom, and a process for preparing the same.
Patent DE-69806354-T2 (DE)
Inventor: BLOT ESTELLE
IPC: C09D4/06
Filed: 1998-03-09
Granted: 2003-01-23
Abstract: The invention concerns traffic paint compositions and a method for reducing the delay for resumption of traffic on a newly marked road with a traffic paint composition with base of a hardenable polymer solution in at least a reactive monomer which can be: a solution of one or several unsaturated polyesters in at least one ethylenically unsaturated monomer polymerizable with the unsaturated polyesters. and/or a solution of one or several (meth)acrylic polymers in at least one monounsaturated (meth)acrylic monomer and, optionally, at least one polyunsaturated (meth)acrylic monomer. This method is characterised in that the polymerisation of the hardenable solution is carried out in the presence of at least a halogenated dibenzoyl peroxide and dibenzoyl peroxide as polymerisation catalyst, and in the presence of a least one polymerisation reaction catalyst.
Patent DE-69809359-T2 (DE)
Inventor: BAGALINI DANTE
IPC: H01H83/02
Filed: 1998-09-14
Granted: 2003-09-04
Abstract: A circuit breaker 10 includes a primary housing 12 containing an operating mechanism 14, the operating mechanism 14 including a plurality of output conductors 16. An earth leakage sensing device comprising an oval-shaped core 20 is mounted in the primary housing 12. Electrically conductive elements 22 are mounted on the output conductors 16 and project through an oval-shaped opening defined by the core 20. Current sensing circuitry and earth leakage sensing circuitry are incorporated in a secondary housing 42, the secondary housing 42 being received within the primary housing 12. <IMAGE>
Patent DE-69813221-T2 (DE)
Inventor: PALUMBO GIANFRANCO
IPC: A61F5/451
Filed: 1998-06-26
Granted: 2004-03-25
Abstract: The present invention relates to a faecal management device with an increased level of comfort. The faecal management device comprises a bag having an aperture, and an anatomically-shaped flange, which surrounds the aperture. The flange provides for adhesive attachment to the perianal area of the wearer. In particular, the bag comprises a wall material having an inner surface and an outer surface with the outer surface being provided with a non-woven layer. In another aspect of the present invention, the faecal management device is used in combination with a disposable diaper. <IMAGE>
Patent DE-69815851-T2 (DE)
Inventor: RIEBE MICHAEL THOMAS
IPC: B05B9/04
Filed: 1998-07-27
Granted: 2004-04-22
Abstract: The invention is directed to a valve for an aerosol container for dispersing a suspension or solution of a medicament in a liquid propellant contained therein. The valve comprises a valve body defining an aperture, a seal mounted at the aperture, and a valve stem having a dispensing passage. The valve stem being slideably moveable through the seal such that in a first position the valve is closed to prevent the medicament and propellant from entering the dispensing passage. The valve stem also being such that in a second position the valve is open to allow the substance to be dispensed through the dispensing passage. The valve seal characterized in that it is constructed from a nitrile-containing rubber and micronized fluorine-containing polymer.
Patent DE-69826301-T2 (DE)
Inventor: DOLL J
IPC: C07D405/14
Filed: 1998-06-15
Granted: 2005-10-13
Abstract: Novel compounds of formula (1.0) are disclosed. In Formula (1.0) a represents N or NO, R<1> and R<3> are halo, R<2> and R<4> are independently H or halo provided that at least one is H, X is C, CH or N, and T represents a five or six membered heterocycloalkyl ring having one or two heteroatoms selected from S or O. Also disclosed are methods of inhibiting farnesyl protein transferase and methods for treating tumor cells.
Patent DE-69827179-T2 (DE)
Inventor: ERNI BERNHARD
IPC: A61P31/04
Filed: 1998-02-02
Granted: 2005-03-10
Abstract: The bacterial phosphotransferase system (PTS) as a drug target system catalyses the uptake and phosphorylation of carbohydrates. It is further involved in signal transduction, e.g. catabolite repression, chemotaxis, and allosteric regulation of metabolic enzymes and transporters. It is ubiquitous in bacteria but does not occur in eukaryotes. This uniqueness and the pleiotropic function make the PTS a target for the development of new antimicrobials. Assays are described that lead to the discovery of compounds which uncouple the PTS, by acting as protein histidine/cysteine phosphatases. Uncoupling of the PTS leads to inhibition of carbohydrate transport, repression of catabolite controlled genes (e.g. certain virulence genes) and depletion of phosphoenolpyruvate. Compounds from combinatorial libraries with high affinity for phosphoenolpyruvate-protein-phosphatase (Enzyme 1) serve as lead structures for the development of inhibitors and uncouplers of the PTS.
Patent DE-69827785-T2 (DE)
Inventor: KITAZAWA NORITAKA
IPC: C07D491/056
Filed: 1998-03-31
Granted: 2005-12-22
Abstract: A novel 1,4-substituted cyclic amine derivative represented by the following formula or a pharmacologically acceptable salt thereof: <CHEM> (wherein A, B, C, D, T, Y and Z represent each methine or nitrogen; R<1>, R<2>, R<3>, R<4> and R<5> represent each a substituent; n represents 0 or an integer of 1 to 3; m represents 0 or an integer of 1 to 6; and p represents an integer of 1 to 3.) The compound has a serotonin antagonism and is clinically useful as medicament, in particular, for treating, ameliorating and preventing spastic paralysis or central muscle relaxants for ameliorating myotonia.
Patent DE-69834416-T2 (DE)
Inventor: SNIDER R
IPC: H03B1/00
Filed: 1998-10-09
Granted: 2007-04-19
Abstract: A voltage controlled oscillator operable on two widely separated frequency bands, such as 900 MHz and 1.8 GHz for example. The voltage controlled oscillator includes two negative resistance generators (32, 34) which share a common tunable tank circuit (26) and a common impedance matched combiner circuit (28) which provides the RF output (36). The VCO uses only one varactor (30) to tune both frequency bands. Separate negative resistance generators (32, 34) are used to provide optimum frequency selectivity within each frequency band.
Patent DE-69838736-T2 (DE)
Inventor: NELLES JAKOB
IPC: A23L7/109
Filed: 1998-12-03
Granted: 2008-10-30
Abstract: An apparatus and process for producing reduced and low-fat, high-quality pasta filata cheese incorportaes a rice-based cheese substitute into freshly manufactured past filata cheese through a kneading, spraying process that preserves the integrity of the cheese's fiber structure. The rice based cheese substitute may be manufactured on-site with a heated double walled vessel equipped with a high shear mixer and recirculating shear pump.
Patent DE-69901157-T2 (DE)
Inventor: DE VRIES CORNELIS
IPC: B01D53/73
Filed: 1999-01-07
Granted: 2002-10-31
Abstract: The invention relates to a method of recycling a flue gas purification residue which, apart from small amounts of contamination, mainly contains CaCl2, NaCl, CaSO4 and Na2SO4, which method comprises the following steps:   (a) mixing the flue gas purification residue with wash water into a CaCl2 slurry; (b) filtering the CaCl2 slurry, whereby at least one CaCl2 filtrate stream is produced; (c) separating the at least one filtrate stream in a first fraction having a CaCl2 concentration that is lower than a predetermined value, and a second fraction having a CaCl2 concentration that is higher than said predetermined value; and (d) admixing the first fraction to the mixture obtained in step (a), step (a) involving the mixing of the flue gas purification residue with acidic wash water; step (c), the adjustment of the predetermined value of the CaCl2 concentration to a value such that step (d), when admixing the first fraction to the mixture of flue gas purification residue and acidic wash water resulting from step (a), yields a saturated (> 20%) CaCl2 slurry.