baber/WOPTO huggingface dataset:
Patent CA-2390285-A1 (CA)
Inventor: KARDAMI ELISSAVET
IPC: A61K38/18
Filed: 2002-06-11
Abstract: Fibroblast growth factor-2 (FGF-2) is acutely cardioprotective towards non-ischemic as well as ischemic myocardium. The potent mitogenic activity of FGF-2, however, may pose limitations to some of its clinical applications. In this study we examined whether a recombinant FGF-2 mutant (S117A) that is no longer mitogenic retains cardioprotective properties. Administration of S117A FGF-2 after 30 min of ischemia and during reperfusion of the ex vivo perfused rat heart resulted in significant protection (comparable to that of wild type FGF-2) against myocardial contractile dysfunction. In an in vivo study, rat myocardial infarction was induced by irreversible left coronary ligation; S117A FGF-2, or saline, were administered by direct intramyocardial injection into the ischemic left front ventricular wall. One day later: infarct size (assessed histologically), and plasma cTnT levels (assessed by Western blotting) were significantly decreased in the S117A FGF-2-, compared to the saline- treated control group, by 32.2% (P<0.01) or 28.5 % (P<0.01), respectively;systolic pressure, rates of contraction and relaxation and developed pressure, assessed in the Langendorff mode, were significantly increased in the S117A FGF-2 group compared to saline-treated group. One week after infarction, echocardiography showed significantly improved contractile function (ejection fraction, fractional shortening), in the S117A FGF-2 or wild type FGF-2 treated hearts compared to the saline treated group. At 6 weeks post infarction, however, S117 FGF-2-treated hearts had similar scar size and contractile function (systolic pressure, developed pressure, rates of contraction and relaxation, ejection fraction, fractional shortening) to the saline-treated group, while wild type FGF-2-treated hearts continued to display significantly improved contractility and reduced scar size. The wild type-, but not S117-, FGF-2-treated group had significantly increased microvessel density at or near the scar area. It is concluded that acute cardioprotection by FGF-2 against ischemia and/or reperfusion -induced contractile dysfunction and tissue damage is independent of its mitogenic/ angiogenic activity.   Thus the non-mitogenic, non-angiogenic S117 FGF-2 may serve as an agent of secondary injury prevention during early (one week) management of myocardial infarction and re-establishment of blood flow. Long-term protection of underperfused myocardium is likely to require increased vessel formation, and the mitogenic/angiogenic activity of wild type FGF-2.
Patent CA-2390649-A1 (CA)
Title: 5-aryl-1h-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them
Inventor: PASCAL JEAN-CLAUDE
IPC: C07D405/04
Filed: 2000-11-06
Abstract: The invention relates to 5-aryl-1H-1,2,4-triazole com-pounds of formula (I) in which R1, R2, R3 and R4 are as defined in the specification.These compounds are potent and selective COX-2 inhibitors.The invention also relates to pharmaceutical compositions comprising these compounds.
Patent CA-2391610-A1 (CA)
Inventor: BOIES ROBERT
IPC: A61F13/15
Filed: 2002-07-16
Abstract: Cette invention a pour but d'améliorer le comfort pour les personnes (hommes et femmes) souffrant de manque de contrôle de la vessie urinaire (incontinence) soit en dormant, soit éveillé, ce qui a pour effet de mouiller le matelas et/ou les caleçons (sous vêtement ) et le pantalon, selon la situation. L'avantage majeur de cette invention est que la pièce absorban t farine (no 10 pour femmes) peut être continuellement recyclée, c'est à dire être enlevée pour être lavée et réutilisée autant de fois qu'on le désire, contrairement aux appareils absorbant farine connus actuellement qui sont jetables après une seule utilisation; les utilisateurs doivent continuellement acheter de nouveaux appareils. L'appareil proposé ici a donc deux avantages intéressant s: il permets une amélioration du comfort de par sa conception technique même et permets des économies considérables d'argent long terme.
Patent CA-2395727-A1 (CA)
Inventor: MICHIE DAVID
IPC: G06Q30/00
Filed: 2000-12-21
Abstract: Périphérique informatique tel qu'une souris et un procédé destiné à la promotion d'un commerçant (34a) utilisant ce périphérique informatique (10). On fournit un service marketing à plusieurs commerçants qui sont intéressés par la promotion d'une activité commerciale. Le service marketing consiste à fournir des périphériques informatiques "spécifiques aux commerçants" aux destinataires présélectionnés ou directement au commerçant. Les dispositifs sont configurés de manière spécifique pour chacun des commerçants; cela consiste à programmer des informations sur le site Web associées au commerçant ou un signal de déclenchement d'accès au site Web dans les périphériques informatiques. Le logo de la compagnie, son adresse Web ou d'autres informations spécifiques au commerçant sont également présentes à la surface du périphérique informatique. Ces dispositifs spécifiques aux commerçants sont distribués entre les récipients présélectionnés, p.ex., entre les clients actuels ou potentiels ou les vendeurs du commerçant. Les destinataires peuvent automatiquement accéder à un ou plusieurs sites Web du commerçant en actionnant simplement l'interrupteur Web sur leur dispositif.
Patent CA-2396210-A1 (CA)
Title: Method for cloning animals with targetted genetic alterations by transfer_of long-term cultured male or female somatic cell nuclei, comprising artificially-induced genetic alterations, to enucleated recipient cells
Inventor: YANG XIANGZHONG
IPC: C12N5/10
Filed: 2001-01-04
Abstract: An improved method of nuclear transfer employing long-term cultured somatic cells as the donor cells and enucleated oocytes as the recipient cells to produce dividing cybrids. Such cybrids are useful for developing viable animals clones when nurtured in a suitable host environment.
Patent CA-2397632-A1 (CA)
Title: Appareil refrigerant
Inventor: NEWMAN BRIAN
IPC: F25D31/00
Filed: 2001-01-16
Abstract: Appareil réfrigérant (1) pour le refroidissement brusque de récipients à boisson (44), comprenant un réservoir à gaz liquide (3), en communication de fluide avec une buse de refroidissement (4), sous la commande d'une vanne (41) contrôlée par une unité de commande (6), de telle sorte que le récipient à boisson puisse être refroidi par une quantité dosée de gaz liquide vaporisé à partir de la buse de refroidissement. Le réservoir est muni d'un orifice de mise à l'air libre (36) destiné à empêcher une accumulation de gaz liquide vaporisé dans la tuyauterie et/ou le réservoir.
Patent CA-2397952-A1 (CA)
Inventor: MCMICHAEL JOHN
IPC: C12N15/45
Filed: 2000-12-22
Abstract: The present invention relates to a treatment for animals having canine distemper by administering a composition comprising an attenuated canine distemper virus a sub-vaccine virus level effective to alleviate symptoms canine distemper. The invention also provides a treatment for animals having canine distemper by administering a composition comprising an attenuated canine measles virus a sub-vaccine virus level effective to alleviate symptoms canine distemper.
Patent CA-2398599-A1 (CA)
Title: Systeme de radiocommunication comprenant un dispositif de station de base et un terminal de communication
Inventor: YOSHI ISAMU
IPC: H04W28/22
Filed: 2001-11-27
Abstract: Dans un système de radiocommunication doté d'un système HDR et d'un système IS-2000 intégrés, si une demande d'interruption est envoyée depuis un système IS-2000 en direction d'une station mobile (101) effectuant une communication par paquets à vitesse élevée dans le système HDR, une station de base (105) alloue une ressource de communication présentant un niveau de priorité de station mobile (101) supérieur au niveau correspondant à l'absence de demande d'interruption. Selon l'invention, on peut utiliser un système de radiocommunication combinant efficacement les services du système HDR et du système IS-2000 grâce à une exploitation appropriée de ces deux systèmes, ainsi qu'une station de base et un terminal de communication destinés à ce système de radiocommunication.
Patent CA-2400822-A1 (CA)
Title: Electric rotary machine
Inventor: TEMMEN KATRIN
IPC: H02K3/40
Filed: 2001-02-10
Abstract: The invention relates to an electric rotary machine (2), especially a high- voltage generator. The aim of the invention is to provide such a machine wit h a more efficient cooling and a good insulation. To this end, the high voltag e conductors (14) are embedded in channels (12) via a special ceramic powder embedding material (20). Said embedding material (20) has a good thermoconductivity, excellent electrical insulation properties and contains especially aluminum oxide and aluminum nitride as the powder components.</SD OAB>
Patent CA-2401281-A1 (CA)
Inventor: GOSWAMI SULIP KUMAR
IPC: A01H5/00
Filed: 2001-02-26
Abstract: L'invention concerne une plante transgénique à androstérilité cytoplasmique préparée par édition de l'ARN pour exprimer le gène nad 9 non édité permettant de désactiver la production d'ATP dans la mitochondrie des plantes, ainsi qu'un procédé de sa préparation. Ledit procédé consiste à cloner un gène nad 9 non édité par digestion du produit PCR obtenu à partir de l'ADN mitochondrial afin d'obtenir pNG3; à cloner la récolte à gène nad 9 non édité avec la séquence de ciblage sous le promoteur d'ubiquitine et le terminateur NOS pour obtenir pNG11; à co-bombarder des produits pNG11 comme indiqué dans le descriptif avec le gène hygromycine (produit pLAU6 hph) pour générer des plantes contenant le gène nad 9 non édité; à analyser le produit nad 9 (pNG11) à l'aide d'une plante de contrôle présentant un gène nad 9 édité, pGN10, pour déterminer la présence du gène nad 9.
Patent CA-2402442-A1 (CA)
Title: Verification facultative du contenu televisuel interactif
Inventor: DUREAU VINCENT
IPC: H04N21/43
Filed: 2001-03-08
Abstract: L'invention concerne un système et un procédé mis en oeuvre dans un système de télévision interactive, l'objet étant de réguler sélectivement la vérification du contenu télévisuel interactif livré à un destinataire avec notification d'identifier le contenu qui peut être éprouvé et, une fois le contenu éprouvé livré au destinataire, les procédures de vérification du contenu éprouvé sont bloquées. La notification peut être envoyée avant, ou en même temps que le contenu éprouvé. On peut l'envoyer par le même moyen de transmission que le contenu ou par un n'importe quel moyen de livraison. Elle peut identifier, positivement ou négativement, le contenu éprouvé; Elle peut utiliser des caractères de remplacement dans le processus d'identification. Le contenu éprouvé peut être identifié par sa source (par exemple un canal de confiance) ou par référence au contenu lui-même. La notification peut contenir une échéance au delà de laquelle elle n'est plus valable. La notification peut également contenir un identificateur et un numéro de version, de sorte qu'une notification ultérieure ayant le même identificateur et un numéro de version ultérieur annule et remplace la notification la précédant.
Patent CA-2407640-A1 (CA)
Inventor: LEBO STUART E JR
IPC: C04B28/02
Filed: 2001-04-11
Abstract: An improved non-dispersing set retarder additive for foamed cements, cement compositions containing the additive, and methods of cementing in a subterranean zone penetrated by a well bore are provided. The set retarder additive includes a blend of a sulfonated lignin, preferably a lignosulfonat e, with an alkali lignin, preferably a kraft lignin, having an organic sulfur content of 0-3.5 % by weight in a ratio of about 6:4 to 8:2. The methods are  basically comprised of the steps of preparing a foamed cement composition comprised of hydraulic cement, a non-dispersing set retarder, sufficient wat er to form a slurry, sufficient gas to foam the slurry and a foaming and foam stabilizing surfactant present in an amount sufficient to facilitate the formation of the foam and stabilize the foamed cement composition.
Patent CA-2408230-A1 (CA)
Title: Patient point of care computer system
Inventor: REEDER RYAN A
IPC: G06F19/00
Filed: 2001-05-04
Abstract: A patient monitoring system comprises a computer (12), an input device (22, 26, 28, 30, 34, 35, 36) coupled to the computer (12) and configured to input patient information, and first and second display screens (18, 20) coupled to the computer (12). The computer (12) displays a first portion of the patient information on the first display screen (18) and a screen portion of the patient information on the second display screen (20).
Patent CA-2410322-A1 (CA)
Inventor: OSMAN FARHAT
IPC: C12M1/00
Filed: 2001-05-22
Abstract: A device having a processing chamber, particularly for electroelution and/or  dialysis of a substance carried in a sample with respect to an external liqu id medium. The chamber is closed at one end and has an opening at the other longitudinal end sufficiently large to permit a sample, and in particular a gel contained sample, to be inserted thereinto. The chamber has a pair of portals laterally disposed with respect to the opening. The portals are covered with a typically tubular membrane, which is sealingly fixed onto an outside surface of the housing defining the chamber, typically by means of a  tubular sleeve having portals that align with the portals of the chamber, vi a an annular sealing arrangement. The device provides high yield recovery, sav es time, and allows for relatively easy handling specially regarding loading an d unloading of small volume of samples to be dialyzed or inserting the slice o f gel containing the macromolecule sample. The device may be used in an open manner by partially immersing the same in the liquid medium with the opening  above the liquid surface. Optionally, the device may be closed and hermetically sealed if so desired by means of a cap, and thus immersed in a liquid medium.
Patent CA-2411156-A1 (CA)
Inventor: OHARA MINORU
IPC: F01D11/08
Filed: 2002-11-05
Abstract: A tip of rotor blade which rotates is an abradable surface (14).  An inner wall of a shroud (20) as a jacket for the rotor blade is an abrasive surface (23). A part of an abrasive particle (13) protrudes from the abradable surface (14). When the tip of the rotor blade which rotates contacts the inner wall of the shroud, the protruding section (13a) of the abrasive particle slides with the abrasive surface (23) so as to be ground. By doing this, a turbine which can maintain an appropriate clearance between the rotor blade and the shroud and can be used for a long period under high-temperature conditions with easy restoration and remaking thereof.
Patent CA-2412108-A1 (CA)
Title: Message sender status monitor
Inventor: SMITH THOMAS M
IPC: H04L12/58
Filed: 2002-11-14
Abstract: A message sender status monitor is used to determine the communication status of the sender of an electronic message. In the case of email, upon the recipient opening an email, a query is launched to a "status registry" to determine if the sender of the email is currently logged in to the communication network, or if the sender is currently on the telephone, or currently using a cell phone, etc. This status information is then used by the recipient of the email to determine the communication medium used to send a reply to the email sender. For example, if the status information indicates that the message sender is currently logged in to the data network, the recipient can respond using "instant messaging" (considered, therefore, to be a more efficient type of response that merely responding with an email message).
Patent CA-2412903-A1 (CA)
Inventor: LINDBLOM PETER
IPC: G02B17/00
Filed: 2001-06-07
Abstract: The invention concerns a system for achieving an optical image of an object (136), and/or for achieving optical collimation (137) of light from a light source (130), comprising a concave mirror (131; 134), the surface normal of which forms an angle with the incident light in a beam. A negative lens (132;  133) that co-operates with the concave mirror is arranged in the incident and/or exit beam paths such that an image with eliminated or reduced imaging aberrations is achieved in a focal plane (135), and/or that the exit light from a light source (130) is collimated (137).
Patent CA-2412929-A1 (CA)
Title: Seed meter brushes forming a transport seed puddle
Inventor: HAGEN MATTHEW BRIAN
IPC: A01C7/04
Filed: 2002-11-27
Abstract: A seeding machine having a main seed hopper is in communication with a planting unit by a flexible tube. The planting unit has a horizontal working position and a vertical transport position. The main hopper supplies seed by gravity to the planting unit through the flexible tube. The planting unit is provided with a vacuum seed meter. The seed meter has a seed disc with a vacuum side and a working seed puddle side. An isolator brush; arranged in a chordal manner on the seed puddle side of the seed disc, defines the discharge area of the seed meter. A  first brush intersecting the isolator brush extends downwardly and radially inward along the seed disc. The first brush, together with the isolator brush, defines boundaries of a transport seed puddle when the planting unit is pivoted into its vertical transport position. A second brush extends downwardly and radially inward along the seed disc. The first and second brushes define a seed return gap through which seed from the top of the seed meter can be returned to the working seed puddle.
Patent CA-2413792-A1 (CA)
Inventor: WEGEHAUPT FRANK
IPC: B05B12/06
Filed: 2002-12-10
Abstract: Process and device for spraying a moving fibrous material web with at least one nozzle. The process includes feeding a spray medium volume flow of the at least one nozzle via at least one valve and damping or weakening pulsations occurring in the volume flow of the spray medium. The device includes at least one nozzle, at least one valve arranged to feed a spray medium volume flow to said at least one nozzle, and a damping element arranged to damp or weaken pulsations occurring in the volume flow of the spray medium.
Patent CA-2416540-A1 (CA)
Title: Fast-switching reversible electrochemical mirror (rem)
Inventor: ROWELL PETRA V
IPC: G02F1/1506
Filed: 2001-07-03
Abstract: A reversible electrochemical mirror (REM) includes a first electrode and a second electrode, one of which is substantially transparent to at least a portion of the spectrum of electromagnetic radiation. An essentially nonaqueous electrolytic solution, disposed between the first and second electrodes, contains ions of an electrodepositable metal having a molar concentration of more than 0.5 M. the electrolytic solution also contains halide and/or pseudohalide anions having a total molar concentration ratio of at least 2:1 relative to the concentration of the electrodepositable metal cations. A negative electrical potential applied to the first electrode causes deposited metal to be dissolved from the second electrode into the electrolytic solution and to be electrodepotsited from the solution onto the first electrode to form a mirror deposit, thereby affecting the reflectivity of the REM device for electromagnetic radiation. A positive electrical potential applied to the first electrode causes deposited metal to be dissolved from the first electrode into the solution and electrodeposited from the solution onto the second electrode, thereby decreasing the reflectivity of the REM mirror. It is usually necessary to apply a surface modification layer to the first electrode to ensure uniform nucleation so that a mirror electrodeposit having high reflectivity is obtained. The high molar concentration of mirror metal cations attained in essentially nonaqueous solvents by use of at least a 2:1 molar ratio of halide and/or pseudohalide anions to electrodepositable metal ions in the electrolyte provides the fast switching speed, inherent electrolyte stability, high deposit quality, good deposit erasure and long cycle life needed for practical applications.  Increases above this 2:1 molar ratio may be required to optimize the device performance.
Patent CA-2417790-A1 (CA)
Inventor: WOODSIDE SHANE H
IPC: G01M11/00
Filed: 2003-01-30
Abstract: A system for determining response characteristics, insertion loss and group delay, of an optical component by applying a sweeping wavelength optical signal that is modulated with an RF signal, measuring the insertion loss and group delay at a series of wavelengths and correlating the measurements to wavelengths. A method for synthesis of an effective modulation frequency in determining the group delay response characteristics of an optical component by obtaining a series of measurements over a sample optical spectrum using, a given modulation frequency and calculating a weighted average of the group delays in the series of measurements giving a result substantially equivalent to a measurement taken using a modulation frequency equal to the effective modulation frequency.
Patent CA-2418257-A1 (CA)
Inventor: PERRIER MICHEL
IPC: H01M50/414
Filed: 2003-01-30
Abstract: A metallic lithium rechargeable electrochemical accumulator, including at least one lithium metal electrode and at least one polymeric electrolyte gel. The accumulator is capable of operating at temperatures from −20 to 60° C., essentially without formation of lithium dendrites on the whole surface of the metallic lithium electrode. The above is also wherein a particularly long life, even with intensive use at low temperature. The rechargeable accumulator can be produced by use of a production method with particular application of temperature control during the specific production stages. As a result of the extremely high electrochemical performance of said accumulator, in particular the remarkable stability thereof, the accumulator can be used in new application fields such as hybrid vehicles, electric vehicles and emergency supply systems such as those of the UPS type.
Patent CA-2418434-A1 (CA)
Title: Processes for preparing 3.3-dimethylbutyric acid
Inventor: JACKMAN DENNIS E
IPC: C07C51/353
Filed: 2003-02-03
Abstract: A process for preparing 3,3-dimethylbutyric acid includes the steps of reacting trimethylpyruvic acid with a first portion of hydrazine to obtain a ketazine, and treating the ketazine with base and a second portion of hydrazine.
Patent CA-2418645-A1 (CA)
Title: Procede et appareil destines a un raccordement metallurgique et mecanique combinee
Inventor: DANIEL DAVID L
IPC: B23K1/00
Filed: 2001-08-23
Abstract: L'invention concerne un raccordement métallurgique et mécanique combiné servant à joindre des éléments, tels que des conduites (10, 20), la matière liante à diffusion amorphe (40) étant placée au niveau des surfaces d'appariement ou attenantes (34, 36) dans le joint mécanique. On comprime la matière liante sous pression et on applique de la chaleur pour provoquer la diffusion de ladite matière dans le raccordement mécanique.
Patent CA-2419357-A1 (CA)
Title: Polarization scrambler and optical network using the same
Inventor: IWATSUKI KATSUMI
IPC: G02F1/01
Filed: 2003-02-20
Abstract: To generate light with the degree of polarization zeroed and the spread of an optical spectrum suppressed even with temporal overlapping between optical pulses each of which is polarized orthogonally to the succeeding pulse, a polarization scrambler is provided with an optical pulse generator (10) that generates optical pulses with an intensity waveform repetition period T/2 and an electrical field period T in which the same intensity waveform is repeated every repetition period T/2 and in which phase is inverted every repetition period T/2, and an orthogonal polarization delay unit (20) which receives each of the optical pulses, separates the optical pulse into two optical pulses with orthogonal states of polarization, and relatively shifts the temporal position of one of the two optical pulses from that of the other optical pulse by (2n-1) T/4 (n is a natural number) to generate light in which each pulse is polarized orthogonally to a succeeding pulse.