baber/WOPTO huggingface dataset:
Patent CY-1110883-T1 (CY)
Title: Εγκατασταση για την παραγωγη και/ή συναρμολογηση προϊοντων
Inventor: WOBBEN ALOYS
IPC: E04H15/02
Filed: 2010-11-09
Abstract: Προτείνεται μία εγκατάσταση παραγωγής. Αυτή η εγκατάσταση παραγωγής αποτελείται από μία κατασκευή σκηνής (1), όπου η οροφή αυτής εγκατάστασης συγκρατείται από έναν τουλάχιστον φορέα (ορθοστάτης στήριξης 4) και στον ίδιο τον φορέα επίσης διαμορφώνεται συγχρόνως μία τουλάχιστον εγκατάσταση (2, 3) για την ανύψωση, ή βύθιση, ή κίνηση των προϊόντων ή των εξαρτημάτων τους, πχ μία κατασκευή γερανού. Επίσης γνωστοποιείται μία διάταξη παραγωγής με μία κεντρική αίθουσα, η οποία παρουσιάζει συνδεόμενες θέσεις για τη σύνδεση των μονάδων παραγωγής.
Patent CY-1112252-T1 (CY)
Inventor: SCHNEIDER BRYAN P
IPC: G01N33/50
Filed: 2011-11-22
Abstract: Methods for determining whether a patient in at particular risk of hypertension associated with anti-VEGF treatment or has a greater likelihood of benefiting from anti-VEGF therapy by screening a sample isolated from the patient for specific genomic polymorphisms.
Patent CY-1112624-T1 (CY)
Inventor: OJALA MIKA
IPC: F28F13/12
Filed: 2012-02-28
Abstract: The present invention relates to a single pipe collector for a heat pump installation. The collector comprises a pipe (12) intended for installation in a heat pump plant, in which pipe a heat transfer liquid circulates in a closed cycle for conveyance of heat that is absorbed from a heat source to a heat pump and return of the heat transfer liquid back to the heat source. The inward surface (14) of the pipe has an uneven surface structure that comprises indentations and/or elevations (16). The present invention also relates to heat pump plant comprising the collector.
Patent CY-1113473-T1 (CY)
Title: ΠΡΟΣΤΑΤΕΥΤΙΚΟΣ ΠΑΡΑΓΩΝ ΓΙΑ ΑΜΦΙΒΛΗΣΤΡΟΕΙΔΙΚΟ ΝΕΥΡΩΝΙΚΟ ΚΥΤΤΑΡΟ ΠΟΥ ΠΕΡΙΕΧΕΙ ΠΑΡΑΓΩΓΟ ΠΡΟΣΤΑΓΛΑΝΔΙΝΗΣ F2α ΩΣ ΔΡΑΣΤΙΚΟ ΣΥΣΤΑΤΙΚΟ
Inventor: ISHIDA NARUHIRO
IPC: A61P27/02
Filed: 2012-10-16
Abstract: Ένα αντικείμενο της παρούσας εφεύρεσης είναι να βρεθεί μια νέα φαρμακευτική εφαρμογή για ένα παράγωγο προσταγλανδίνης F2α. Έχει βρεθεί ότι το παράγωγο προσταλανδίνης F2α αναστέλλει τον προκαλούμενο από γλουταμικό θάνατο αμφιβληστροειδικού νευρωνικού κυττάρου με τρόπο που εξαρτάται από την συγκέντρωση σε εμβρυϊκά αμφιβληστροειδικά νευρωνικά κύτταρα αρουραίου, με άλλα λόγια, το παράγωγο προσταγλανδίνης F2α δρα απευθείας επί των αμφιβληστροειδικών νευρωνικών κυττάρων και δεικνύει προστατευτικό αποτέλεσμα. Ακολούθως, το παράγωγο προσταγλανδίνης F2α είναι χρήσιμο για την αποτροπή ή την θεραπεία μιας οφθαλμικής ασθένειας που συνδυάζεται με βλάβη αμφιβληστροειδικού νευρωνικού κυττάρου.
Patent CY-1113619-T1 (CY)
Title: Συσκευασια για αντικειμενα που σχετιζονται με καπνο
Inventor: HOLLOWAY STEVE
IPC: B65D85/10
Filed: 2012-11-27
Abstract: Συσκευασία (1) για αντικείμενα που σχετίζονται με καπνό που περιλαμβάνει εξωτερικό περίβλημα (2), ένα καπάκι (4) το οποίο προσαρμόζεται έτσι ώστε να κλείνει την άνω πλευρά του εξωτερικού περιβλήματος (2) και το οποίο μπορεί να περιστραφεί γύρω από γραμμή άρμοσης και ένα εσωτερικό περίβλημα (6). Το εσωτερικό περίβλημα (6) περιλαμβάνει πλειάδα αντικειμένων που σχετίζονται με καπνό και μπορεί να μετατοπισθεί στο εσωτερικό περίβλημα (2) από μια θέση απόσυρσης, σε μια προχωρημένη θέση, που επιτρέπει την πρόσβαση στα αντικείμενα που σχετίζονται με καπνό. Το άνοιγμα (20) στο εξωτερικό περίβλημα (2) εκθέτει μέρος του εσωτερικού περιβλήματος (2) και επιτρέπει την μετάδοση μιας δύναμης πάνω στο εσωτερικό περίβλημα (6) για την μετακίνηση του εσωτερικού περιβλήματος (6). Ο συνδετήρας (50) σπρώχνει το καπάκι (4) στην ανοικτή του κατάσταση όταν το εσωτερικό περίβλημα (6) μετακινείται στην προχωρημένη του θέση και τραβάει το καπάκι (4) στην κλειστή του κατάσταση όταν το εσωτερικό περίβλημα (6) κινείται προς τη θέση απόσυρσης του.
Patent CY-1113786-T1 (CY)
Title: Εξασθενημενοι ιοι πολιομυελιτιδας
Inventor: MACADAM ANDREW
IPC: A61K39/13
Filed: 2013-03-11
Abstract: Η εφεύρεση παρέχει εξασθενημένο ιό πολιομυελίτιδας ο οποίος δεν έχει αναντιστοιχία ζεύγους βάσεων στον μίσχο (α) ή (β) της επικράτειας V της περιοχής 5' μη-κωδίκευσης του γονιδιώματος αυτού, όπου τουλάχιστον επτά από τα ζεύγη βάσεων στους μίσχους (α) και (β) είναι τα ζεύγη βάσεων U-A ή A-U.
Patent CY-1116618-T1 (CY)
Title: Διαδικασια για την παρασκευη ενος διφαινυλο-2-υλοκαρβαμικου οξεος
Inventor: COLSON PIERRE-JEAN
IPC: C07D211/46
Filed: 2015-08-18
Abstract: Η εφεύρεση παρέχει μια διαδικασία για την παρασκευή ενός ενδιάμεσου προϊόντος που είναι χρήσιμο για τη σύνθεση του διφαίνυλο-2-υλοκαρβαμικού οξέος 1-(2-{[4-(4-καρβαμυλοπιπεριδιν-1-υλομέθυλο) βένζυλο] μεθυλάμινο}αίθυλο) πιπεριδιν-4-υλο εστέρα, και μια διαδικασία παρασκευής μιας κρυσταλλικής ελεύθερης βάσης του εστέρα.
Patent CY-1117886-T1 (CY)
Title: Υδροχλωρικη 4-[2-[[5-μεθυλ-1-(2-ναφθαλενυλ)-1η-πυραζολ-3-υλ]οξυ]αιθυλ]μορφολινη και επιδιαλυτωματα
Inventor: BERENGUER MAIMÓ RAMÓN
IPC: C07D231/22
Filed: 2016-08-08
Abstract: Η παρούσα εφεύρεση αναφέρεται σε πολύμορφα και επιδιαλυτώματα του υδροχλωρικού άλατος της 4-[2-[[5-μεθυλ- 1-(2-ναφθαλενυλ)-1Η-πυραζολ-3-υλ]οξυ]αιθυλ]μορφολίνης(Ρ027), σε διεργασίες για την παρασκευή τους και σε φαρμακευτικές συνθέσεις που τα περιέχουν.
Patent CY-1118829-T1 (CY)
Title: Ανασταλτικος vegf σταθερων και διαλυτων αντισωματων
Inventor: BORRAS LEONARDO
IPC: C07K16/22
Filed: 2017-04-12
Abstract: Η παρούσα εφεύρεση σχετίζεται με διαλυτούς και σταθερούς ανοσοπροσδέτες anti-VEGF που περιλαμβάνουν CDR από μονοκλωνικά αντισώματα κουνελιού. Τα εν λόγω αντισώματα είναι σχεδιασμένα για τη διάγνωση και/ή τη θεραπεία διαταραχών που προκαλούνται από τον VEGF. Επίσης περιλαμβάνονται τα υβριδώματα, τα νουκλεϊκά οξέα, οι φορείς και τα κύτταρα ξενιστή για την έκφραση των ανασυνδυαστικών αντισωμάτων της εφεύρεσης, μέθοδοι για την απομόνωση τους και η χρήση των εν λόγω αντισωμάτων στην ιατρική.
Patent CY-1121106-T1 (CY)
Title: Συζευγματα λιπαρων οξεων της κουετιαπινης, διαδικασια παρασκευης και χρησης της
Inventor: MICKLE TRAVIS
IPC: A01N43/00
Filed: 2019-01-14
Abstract: Η παρούσα τεχνολογία παρέχει μια νέα κατηγορία προφαρμάκων της κουετιαπίνης που μπορούν να συντεθούν με χημική σύζευξη λιπαρών οξέων στην κουετιαπίνη. Παρέχονται επίσης φαρμακευτικές συνθέσεις και μέθοδοι σύνθεσης συζευγμάτων της παρούσας τεχνολογίας. Επιπλέον, παρέχονται μέθοδοι θεραπείας των ασθενών με τις συνθέσεις της παρούσας τεχνολογίας.
Patent CY-1121419-T1 (CY)
Title: Αναστολη της φουκοσυλιωσης των πρωτεϊνων in vivo χρησιμοποιωντας αναλογα φουκοζης
Inventor: SENTER PETER
IPC: A61K31/7012
Filed: 2019-02-20
Abstract: Η εφεύρεση προβλέπει μεθόδους και συνθέσεις για την αναστολή της φουκοσυλίωσης των πρωτεϊνών, συμπεριλαμβανομένων των αντισωμάτων, in vivo με τη χορήγηση ενός αναλόγου φουκόζης.
Patent HR-P20090468-T1 (HR)
Inventor: TUERDI HUJI
IPC: C07D209/96
Filed: 2009-09-03
Abstract: Spoj formule (I): ili njegov stereoziomer ili farmaceutski prihvatljiva sol ili solvat, naznačen time što: prsten A je C6-10 aril supstituiran sa 0-5 R1, ili 5- do 10-člani heterociklus koji sadrži: atome ugljika i 1-4 heteroatoma izabrana od N, NR11, O i S(O)p, gdje je navedeni heterociklus supstituiran sa 0-5 R1;prsten B je fenil ili naftil supstituiran sa 0-4 R7, ili 5- do 10-člani heteroaril koji sadrži: atome ugljika i 1-4 heteroatoma u prstenu koji su izabrani od N, NR11, S(O)p i O, gdje je navedeni heteroaril supstituiran sa 0-4 R7;prsten D je supstituiran sa 0-5 R6a i izabran od: gdje je D1 jednako 5- do 7-člani karbociklični prsten ili 5-6-člani heterociklus koji sadrži: atome ugljika i 0-3 heteroatoma u prstenu koji su izabrani od N, NR11, O i S(O)p, i 0-2 karbonil grupe, i 0-3 dvogube veze; W je O ili S; X2 je -(CR16R17)S-, ili -(CR16R17)tC(O)(CR16R17)r-;R1 je, nezavisno u svakom slučaju, H, =O, F, Cl, Br, I, CF3, -CF2CF3, OCF3, -OCF2CF2H, -OCF2CF3, SiMe3, -(CRfRf)r-ORc, SRc, CN, NO2, -(CRfRf)r-NR12R13, -(CRfRf)r-C(O)Rc, -(CRfRf)r-CO2Rc, -(CRfRf)rC(O)NR12R13, -C(O)NR14(CRfRf)tN12R13, -(CRfRf)r-OC(O)NR12R13, -(CRfRf)rNR14C(O)NR12R13, -(CRfRf)r-NR14C(O)Rd, -(CRfRf)r-NR14C(O)ORh, -NR14(CRfRf)nC(O)Rd, -NR14CO(CRfRf)nORc, -(CH2)r-CR13(=NORc), -S(O)pNR12R13, -(CRfRf)r-NR14S(O)pNR12R13, -NR14SO2CF3, -NR14S(O)pRd, -S(O)2CF3, -S(O)Rd, -S(O)2Rd -OP(O)(OEt)2, -O(CH2)2OP(O)(OEt)2, 4,4,5,5-tetrametil-1,3,2-dioksaborolanil, C1-8 alkil supstituiran sa 0-2 Ra, C2-8 alkenil supstituiran sa 0-2 Ra, C2-8 alkinil supstituiran sa 0-2 Ra, -(CRfRf)r-C3-13 karbociklični prsten supstituiran sa 0-5 Rb, ili -(CRfRf)r-5- do 10-člani heterociklus koji sadrži: atome ugljika i 1-4 heteroatoma koji su izabrani od N, NR11, O i S(O)p, gdje je navedeni heterociklus supstituiran sa 0-5 Rb;alternativno, dva R1 na dva susjedna atoma ugljika su kombinirani sa atomima ugljika za koje su vezani, formirajući 5- do 10-člani karbociklični ili heterociklični prsten koji sadrži: atome ugljika i 0-3 dodatnih heteroatoma koji su izabrani od N, NR11, O i S(O)p, i 0-2 karbonil grupe, pri čemu je navedeni karbociklični ili heterociklični prsten supstituiran sa 0-4 Rb;R6a je, nezavisno u svakom slučaju, =O, F, Cl, Br, I, -(CRiRi)r-ORc, SRc, CN, NO2, CF3, OCF3, -CF2CF3, -OCF2CF2H, -OCF2CF3, -(CRfRf)r-NR12R13, -C(O)Rc, -(CRfRf)r-C(O)ORc, -(CRfRf)r-C(O)NR12R13, -(CRfRf)r-NR14C(O)Rd, -S(O)pNR12R13, -S(O)Rd, -S(O)2Rd, Si(Me)3, Si(C1-4 alkil)3, C1-4 haloalkil, C1-4 haloalkiloksi-, C1-4 alkiloksi-, C1-4 alkiltio-, C1-C4 alkil-C(O)-, C1-4 alkil-O-C(O)-, C1-4 alkil-C(O)NH-, C1-8 alkil supstituirn sa 0-1 Ra, C2-8 alkenil supstituiran sa 0-1 Ra, C2-8 alkinil supstituiran sa 0-1 Ra, -(CRfRf)r-C3-10 karbociklični prsten supstituiran sa 0-2 Re, ili -(CRfRf)r-5- do 10-člani heterociklični prsten koji sadrži: atome ugljika i 1-4 heteroatoma koji su izabrani od N, NR11, O i S(O)p, gdje je navedeni heterociklični prsten supstituiran sa 0-2 Re;alternativno, kada su dvije R6a grupe vezane za isti atom uglj
Patent HR-P20100557-T1 (HR)
Inventor: CAZELLES JEROME
IPC: C07D491/113
Filed: 2010-10-13
Abstract: Spoj formule (I): naznačen time što:-	A predstavlja ostatak molekule s antimalaričnom aktivnošću i/ili ostatak koji povećava biodostupnost, kojeg se bira između: ?	dušičnog heterocikla formule (II): u kojoj:-	R i R', koji su istovjetni ili različiti, od kojih svaki predstavlja jedan ili više supstituenata, koji zauzimaju različite položaje na prstenima na koje su vezani, te koje se bira između atoma vodika ili halogena, te -OH, -CF3, arilnih, heteroaril, alkilnih, -O-alkilnih, -NO2 ili -N(Ra,Rb) skupina, ili Ra i Rb, koji su istovjetni ili različiti, predstavljaju atome vodika ili nerazgranate, razgranate ili prstenaste alkilne skupine s 1 do 5 atoma ugljika; najmanje jedan od R ili R' nije atom vodika;-	R4 predstavlja atom vodika ili nerazgranati, razgranati ili prstenasti C1 do C5 alkilni radikal, ili R4 tvori, s atomom ugljika ili dušika, prisutnim u skupini -(Y1)p-(U)p'-(Y2)p''- u formuli (I), 5- do 8-eročlani prsten,-	radikali B1, C1, D1, B2, C2 i D2 predstavljaju atome dušika ili -CH= članove prstena, uzevši da bilo koji od radikala B1, C1 i D1 predstavlja atom dušika, a drugi radikali predstavljaju -CH= članove prstena, ili jedan od radikala B2, C2 i D2 predstavlja atom dušika, a drugi radikali predstavljaju -CH= članove prstena, ili jedan od radikala B1, C1 i D1 i jedan od radikala B2, C2 i D2 predstavljaju atome dušika, a drugi radikali predstavljaju -CH= članove prstena, ?	ostataka formula (IV), (V), (VI), (VII), (VIII), (IX) ili (X), u kojima R, R', Ra i Rb su kao što je definirano u ovom patentnom zahtjevu za spoj formule (II) i R5 predstavlja arilni radikal ili ostatak dušičnog heterocikla, izborno supstituiran s jednom ili više skupina R: R5-CHOH-				(IV) -	p, p' i p'', međusobno neovisno, predstavljaju 0 ili 1, gdje najmanje jedan od p ili p'' je 1,-	Y1 i Y2, koji su istovjetni ili različiti, predstavljaju nerazgranati, razgranati ili prstenasti C1 do C6 alkilenski lanac, koji izborno sadrži jedan ili više aminskih, amidnih, tioamidnih, sulfonilnih, sulfonatnih, sulfonamidnih, karbonilnih, tiokarbonilnih, karboksilnih, tiokarboksilnih, eterskih ili tioeterskih radikala, gdje je navedeni alkilenski lanac, izborno supstituiran s jednom ili više skupina, koje se bira između atoma halogena, hidroksilnih skupina, acetalnih skupina i nerazgranatih, razgranatih ili prstenastih C1 do C5 alkilnih radikala,-	U predstavlja aminski, amidni, tioamidni, sulfonilni, sulfonatni, sulfonamidni, karbonilni, tiokarbonilni, karboksilni, tiokarboksilni, eterski ili tioeterski radikal,-	Z1 i Z2, koji su istovjetni ili različiti, predstavljaju zasićeni ili nezasićeni nerazgranati, razgranati ili prstenasti C1 do C4 alkilenski radikal, gdje jedan od Z1 ili Z2 može biti odsutan, ili kombinacija Z1 + Z2 predstavlja policikličku strukturu koja sadrži N i spojni ugljik Cj,-	R1 i R2, koji su istovjetni ili različiti, predstavljaju atom vodika ili funkcionalnu skupinu koja može povećati topivost u vodi dvojne molekule,-	Rx i Ry zajedno tvore prstenasti peroksid
Patent SI-1507752-T1 (SI)
Title: Ceramic moulded body comprising a photocatalytic coating and method for producing the same
Inventor: THIERAUF AXEL
IPC: C04B41/00
Filed: 2003-05-28
Abstract: An oxide ceramic-based shaped article (A), having a surface which is self-cleaning on contact with rain or spraying with water, has a porous photocatalytically active oxide ceramic surface coating (I) with a specific surface of 25-200 (preferably 40-150) m2/g.  An Independent claim is included for the preparation of (A) by:  (a) forming a suspension by mixing photocatalytically active oxide ceramic powder, extender and/or adhesive and a liquid phase;  (b) applying a layer of the suspension to the oxide ceramic base material; and  (c) hardening the layer to form (I).
Patent SI-1550219-T1 (SI)
Title: Method and arrangement for arithmetically encoding and decoding binary states, corresponding computer program, and corresponding computer-readable storage medium
Inventor: MARPE DETLEF
IPC: H04N7/26
Filed: 2003-05-02
Abstract: The method involves dividing a value range specifying the interval width into representative interval widths and a value range specifying probabilities into representative probability states, defining rules that associate each interval width and probability and computing new interval widths using a representative interval width and probability state, various arithmetic operations and a probability estimation according to the defined rules. The method involves dividing a defined value range for specifying the interval width into representative interval widths and a definable value range for specifying probabilities into representative probability states and defining association rules that associate each interval width and each probability, encoding or decoding the binary states by computing new interval widths using a representative interval width and probability state, various arithmetic operations and a probability estimation in accordance with the defined association rules. Independent claims are also included for the following: (a) an arrangement with at least one processor and/or chip for arithmetically encoding and decoding binary states (b) a computer program for arithmetically encoding and decoding binary states (c) a computer-readable memory medium for storing a computer program for arithmetically encoding and decoding binary states (d) a method of downloading a computer program from an electronic data network, e.g. Internet.
Patent SI-1707349-T1 (SI)
Title: Thermally insulating panel
Inventor: MENTE MARKUS
IPC: B32B3/00
Filed: 2005-12-14
Abstract: The panel includes a porous layer (A) formed in a gas-diffusion-close sheathing, in which the porous layer has pore volume that is partly formed under vacuum. Protective layers (B,10), which are formed in non-under vacuum conditions, are laminated on opposite surfaces of the porous layer. The protective layers are made of mineral fiber layer and wood wool layer.
Patent SI-1591079-T1 (SI)
Title: Locking stent having multiple locking points
Inventor: FLEMING JAMES A III
IPC: A61L31/00
Filed: 2005-04-28
Abstract: A stent (100) includes a lattice of interconnecting elements defining a substantially cylindrical configuration having a first open end and a second open end. The lattice has a closed configuration and an open configuration. The lattice includes a plurality of adjacent hoops (102), wherein at least two hoops are movable to one or more discrete locked positions as the open configuration and at least one hoop interlocks with another hoop at the one or more discrete locked positions (150). Moreover, the stent can be made from a biodegradable or bioabsorbable material.
Patent SI-1732427-T1 (SI)
Title: Household appliance comprising a central actuating system
Inventor: MAZEJ STANISLAV
IPC: A47J43/00
Filed: 2005-03-30
Abstract: The invention relates to a juice extractor or juice centrifuge comprising an actuating element that can be displaced between an idle position and at least one operating position for starting and stopping a drive motor for driving a work tool that is covered by an appliance lid placed on the household appliance, according to the operating mode, and detached by unlocking means. The aim of the invention is to improve the handling of the household appliance. To this end, the actuating element is connected to the unlocking means and can be detached by being shifted into an unlocking position of the appliance lid, preventing the start-up of the drive motor. The inventive embodiment enables the household device to be started in an especially safe manner.
Patent SI-1831209-T1 (SI)
Title: Cdc25 phosphatase inhibitors
Inventor: SIDHU ALBAN
IPC: A61K31/00
Filed: 2005-12-16
Abstract: A subject of the present invention is novel compounds comprising 2 or 3 benzothiazole-4,7-dione- or benzooxazole-4,7-dione-type units, which inhibit the cdc25 phosphatases, in particular cdc25-C phosphatase. These compounds can in particular be used in the treatment of cancer.
Patent SI-2019114-T1 (SI)
Title: Process for the preparation of Drospirenone
Inventor: ANDRIOLO ERIKA
IPC: C07J53/00
Filed: 2007-07-26
Abstract: A process for the preparation of Drospirenone (I) according to the following scheme   
wherein the substituent R is defined in the description. The process improves the product yield and purity by reducing the formation of undesired side-products and is particularly convenient for industrial-scale manufacturing.
Patent DE-3650637-T2 (DE)
Inventor: VAN DER LELY CORNELIS
IPC: A01J5/017
Filed: 1986-01-22
Granted: 1998-04-02
Abstract: The appts. includes a milking parlour, a milking machine and at least one computer. The milking cluster (18) is provided with one or more sensors (33) which determine whether or not the cluster is correctly attached to teats of an udder. The milking operation is switched on only if it is determined that the milking cluster is correctly attached, and attachment repeated if correct attachment fails. A sensor (16) is also proVided to determine whether the animal is in the appropriate position in the milking parlour, the automatic milking operation being discontinued if it is determined that the animal is not in the correct position. An arrangement (2,3,12,27) may also be provided for correcting the posture or positioning of the animal.
Patent DE-3685888-T2 (DE)
Inventor: YAMAUCHI SHINKO
IPC: G06F5/00
Filed: 1986-02-14
Granted: 1993-07-01
Abstract: A binary code processor for processing binary codes which represent at least first and second types of information in different ranges of value comprises a memory (1) for storing the binary codes, a discriminator (3) for generating an identification code to distinguish the first and second information data from the memory (1), a subtractor (4) for compressing the range of value of the binary code in accordance with said identification code, a converter (6) for converting the compressed binary code and the identification code to decimal digital codes in accordance with the identification code, and a further memory (7) for storing the decimal binary codes.
Patent DE-3785864-T2 (DE)
Inventor: COHEN CHARLES MICHAEL DR
IPC: C07K19/00
Filed: 1987-02-20
Granted: 1994-01-20
Abstract: Disclosed is a process for producing a fusion protein comprising epidermal growth factor (EGF) attached through a Glu-residue to a leader. Treatment ofthe fusion protein with a Staphylococcus aureus V8 protease specific for cleaving peptides at a Glu-linkage produces large amounts of the 53 amino acid EGF sequence.The treatment conditions optimize production of the 53 and 51 amino acid EGFs relative to shorter analogs, and take full advantage of the selectivity of the protease.
Patent DE-3789405-T2 (DE)
Inventor: ROBINSON GRAHAM ERNEST
IPC: C07F7/18
Filed: 1987-06-15
Granted: 1994-07-14
Abstract: An improved process for preparing cephalosporins having a 7-position substituent of the formula:- <CHEM> wherein R<a> and R<b> represent hydrogen or alkyl or are joined to form a C3-5 cycloalkyl group, which comprises reacting a 7-amino cephalosporin with a compound of the formula:- <CHEM> wherein R<4> is hydrogen or an amino protecting group, R<1>, R<2> and R<3> are alkyl, aryl or arylalkyl and R<5> is the residue of a displaceable thioester group (R<5>SCO-) and subsequently removing the silyl group and, if necessary, the amino protecting group.
Patent TR-199900155-T2 (TR)
Inventor: DIGAN MARY ELLEN
IPC: A61K39/395
Filed: 1997-07-25
Abstract: En az bir insan serum albumin ögesine, istenirse bir peptit baglayici yoluyla füzyon edilen en az bir IgE-baglayici bölge içeren füzyon polipeptitleri ve bunlarin tuzlari, ve özellikle her birinin amino ve karboksi terminlerinde IgE (Fc RIalfa) beseri yüksek afinite alicisinin alfa-zincirinin hücre disi bir bölgesine füzyon edilen, HSA proteini içeren dimerik füzyon polipeptitler, bunlarin hazirlanmasi islemi, bunlarin hazirlanmasinda araci olan fonksiyonel olarak esit polipeptitler, ve polinükleotit ve oligonükleoit aracilar ve bunlarin vektörleri. Bunlar, IgE-kaynakli, atopik dermatitis, atopik astim ve kronik urtikarya gibi alerjik rahatsizliklar ve bunlarla baglantili rahatsizliklarin önlenmesi ve/veya tedavisi için kullanilmak üzere önerilmektedir.
Patent TR-199901318-T2 (TR)
Inventor: LEACH MATTHEW JAMES
IPC: C11D1/835
Filed: 1997-12-15
Abstract: Tarifname, hem bir yüzeyi temizleyen hem de yüzey üzerinde sonradan biriken kirin çözülmesine yardimci olacak sekilde bir katyonik yüzey aktif cismi katinin çökelmesini saglayan gelistirilmis bilesimleri açiklar. Bunlar, bir yüzey aktif cismi karisimini içerirler; bahsedilen yüzey aktif cismi karisimi asagidakileri içerir: a) toplam yüzey aktif cismine bagli olarak agirlikça en azindan %65 seviyesinde noniyonik yüzey aktif cismi; b) toplam yüzey aktif cismine bagli olarak agirlikça %1'den az bir seviyede anyonik yüzey aktif cismi; c) toplam yüzey aktif cismine bagli olarak agirlikça %0.1-35 seviyesinde, alkil zincirlerin en azindan %10 seviyesinde C18-C26 alkil gruplarini içerdigi bir mono yagli alkil dördüncül amonyum bilesigi olan bir katyonik yüzey aktif cismi; bahsedilen bilesim ayrica en azindan 8.0 degerinde bir pKa'ya sahip bir organik amini agirlikça en azindan % 0.5 seviyesinde içerir.
Patent TR-199901434-T2 (TR)
Inventor: BRUYN GERARD DE
IPC: B23Q3/18
Filed: 1997-12-23
Abstract: Bulus, en az bir parçanin (P) merkezlenmesi ve sikistirilmasini saglayan aletle (1) ilgilidir, parça kumanda için (1) içten geçen ve ayarli sistem için (1) bir destek saglayan bir üst yüzeyi gösteren karterin (2) uç noktasina tasinmis bir kumanda elemani (3), sikistirma elemanlarini (5), merkezleme konumu arasinda sikistirma elemanlarina (5) ait tahrik elemanlarini (6,7,8,10,11) ve (P) parçasi üzerinde destekte olan kumanda elemanin (3) disinda sikistirma takimlarinin (5) çikinti yaptigi sikistirma pozisyonlarinin çogunu içeren tipte bir geçis yolunu içermektedir. Bu bulusa göre, merkezleme ile sikistirma pozisyonlari arasindaki organlarin es zamanli olarak eksenel ve öteleme hareketini saglamak için bahsedilen tahrik elemanlari dizilmistir.