baber/WOPTO huggingface dataset:
Patent NZ-732895-A (NZ)
Title: Methods and compositions for targeted genetic modification through single-step multiple targeting
Inventor: MACDONALD LYNN
IPC: A01K67/027
Filed: 2015-12-18
Abstract: Methods and compositions are provided for making one or more targeted genetic modifications at a target genomic locus within a mammalian cell and for producing non-human animals comprising the modified genomic locus. The methods employ two or more large targeting vectors which are capable of recombining with each other and with the target genomic locus in a single genomic targeting step. The vectors each comprise a nucleic acid insert, wherein the combined size of these inserts is at least 100kb. The methods may also be employed in combination with a nuclease agent. Methods and compositions are also provided for enhancing homologous recombination at a target genomic locus in a cell. The methods employ two or more nucleic acids comprising one or more overlapping sequences. The methods may be employed in combination with a nuclease agent or without a nuclease agent.
Patent NZ-736131-A (NZ)
Title: Compositions and methods for the treatment of epilepsy and neurological disorders
Inventor: KANDULA MAHESH
IPC: C07D409/12
Filed: 2015-02-13
Abstract: The invention relates to the compounds of formula I and formula Ia or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of formula I or formula Ia; and methods for treating or preventing epilepsy, seizures and convulsions may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of epilepsy, seizures and convulsions.
Patent NZ-750268-A (NZ)
Title: Stunner
Inventor: JONES ARTHUR
IPC: A22B3/02
Filed: 2017-06-30
Abstract: An animal stunner for use in livestock/slaughterhouse operations has a piston slideable within an inner chamber, and a fire pressure chamber with an annular configuration disposed adjacent the rearward or central end of the inner chamber. A stunning rod is driven forward by the piston to stun the animal and rearward to retract the rod. A valve system alternately controls flow of the pressurized fluid from the fire pressure chamber to the rearward end of the inner chamber to move the piston and drive the stunning rod. A catch system holds and releases the stunning rod. A compressed fluid supply is used to retract the stunning rod between operation cycles. Handles employing triggers are used by the operator to hold the stunner and to activate the valve system, and cushion mount systems are attached between the handles and stunner housing to absorb shock while operating the stunner. The arrangement reduces wear on the moving parts, and reduces vibration and shock transmitted from the housing to the handle, reduces the volume of air needed as compared to prior art methods, and permits restriction orifices of desired sizes to be used thereby saving on total air volume usage by the stunner.
Patent PT-101085-A (PT)
Inventor: DANSEREAU RICHARD JOHN
IPC: A61P3/14
Filed: 1992-11-20
Abstract: The present invention is directed to a novel enteric-coated oral dosage form of a risedronate active ingredient comprised of a safe and effective amount of a pharmaceutical composition which is comprised of a risedronate active ingredient and pharmaceutically-acceptable excipients. Said dosage forms prohibit the exposure of the risedronate active ingredient to the epithelial and mucosal tissues of the buccal cavity, pharynx, esophagus, and stomach and thereby protects said tissues from erosion, ulceration or other like irritation. Accordingly, the said dosage forms effect the delivery to the lower gastrointestinal tract of said human or other mammal of a safe and effective amount of the risedronate active ingredient, and substantially alleviate the esophagitis or esophageal irritation which occasionally accompanies the oral administration of risedronate active ingredients.
Patent PT-103041-A (PT)
Title: Application of alkylated derivatives of melonamide for extraction by solvents of iron (III) in concentrated chlorinated solutions in industrial chemistry
Inventor: PAIVA ANA PAULA PEREIRA
IPC: C22B3/16
Filed: 2003-11-19
Abstract: The application of alkylated derivatives of melonamide is to the extraction by solvents of Fe (III) of concentrated chlorinated solutions in industrial chemistry, such as N,N'-diphenyl-N,N' dimethyl melonamide, N,N'-diphenyl- N,N'-dimethyl tetradecyl- melonamide and N,N'-dibutyl- N,N'-dimethyl melonamide to the recovery and/or removal of Fe (III) from concentrated chlorinated solutions is shown to be highly advantageous in comparison with commonly used methods. Thus, after an efficient contact of a solution 0.1 M of the compounds in 1.2 dichloroethane with equal volumes of solutions of chloridic acid of 8 to 12 M containing approximately 0.01 M in Fe (III) during 15 minutes, the metallic ion is quantitatively extracted for the organic phase, being re-extracted totally from the organic medium by new contact with an equal volume of water.
Patent PT-115381-A (PT)
Title: Aspersor circular ajustável.
Inventor: RAFAEL TOMÉ GONÇALVES ESCUDEIRO
IPC: B05B3/02
Filed: 2019-03-20
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A UM ASPERSOR CIRCULAR AJUSTÁVEL QUE TEM COMO FUNCIONALIDADE REGAR A TOTALIDADE DE UM CAMPO COM UMA FORMA QUADRANGULAR OU OUTRA E QUE COMPREENDE UMA GUIA (1) PARA QUE UM BOCAL DA ÁGUA (2) E UM CORPO CENTRAL (3) DO ASPERSOR, GIREM EM SIMULTÂNEO E CONCENTRICAMENTE, UM APARELHO DE FIXAÇÃO (5) E UM MECANISMO (7) DE DISPERSÃO DA ÁGUA E DE ROTAÇÃO CORPO CENTRAL (3) E DO BOCAL DA ÁGUA (2).
Patent PT-116410-A (PT)
Title: Gelados comestivéis nutracêuticos à base de ativos funcionais e seus usos
Inventor: ALEXANDRE CABRAL CRAVEIRO
IPC: A23G9/36
Filed: 2020-05-21
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO À PRODUÇÃO, AO PROCESSAMENTO E AO USO DE GELADOS COMESTÍVEIS COMO ALIMENTOS FUNCIONAIS E/OU SUPLEMENTOS. EM PARTICULAR, A PRESENTE INVENÇÃO UTILIZA EXTRATOS VEGETAIS NATURAIS DE FRUTAS E VERDURAS (BLENDS) COMO INGREDIENTES NUTRACÊUTICOS FUNCIONAIS, E WHEY PROTEIN E QUITOSANO COMO COMPONENTES FUNCIONAIS BASE NA SUA COMPOSIÇÃO E FORMULAÇÃO. O INVENTO TAMBÉM ABRANGE A INCLUSÃO DE OUTROS INGREDIENTES FUNCIONAIS, TAIS COMO, PECTINA, PROTEÍNA DO LEITE, FASEOLAMINA, FIBRAS, AGENTES ANTIOXIDANTES, ÁCIDOS GORDOS, PIGMENTOS, OUTROS EXTRATOS NATURAIS, TAIS COMO SPONDIAS MONBIM, ENTRE OUTROS. DEVIDO AS SUAS PROPRIEDADES BENÉFICAS PARA A SAÚDE E O BEM-ESTAR, A PRESENTE INVENÇÃO DESTINA-SE À PROGRAMAS DE EMAGRECIMENTO, PREVENÇÃO E TRATAMENTO DE DOENÇAS E SUPLEMENTAÇÃO DE AMINOÁCIDOS, PROTEÍNAS, VITAMINAS E MINERAIS, E PODE SE APRESENTAR NA FORMA DE SORVETES EM MASSA OU CREME, PICOLÉS, PALETAS, SMOOTHIES, TORTAS, COOKIES, BEBIDAS GELADAS E OUTRAS APRESENTAÇÕES.
Patent PT-118270-A (PT)
Title: Sistema de avaliação do conteúdo de inovação
Inventor: DIEGO TEIXEIRA
IPC: G06Q10/00
Filed: 2022-10-20
Abstract: A INVENÇÃO SE SITUA NO CAMPO TÉCNICO DOS SISTEMAS DE INOVAÇÃO. MAIS ESPECIFICAMENTE, A INVENÇÃO PROVÊ UM SISTEMA DE AVALIAÇÃO DE CONTEÚDO DA INOVAÇÃO QUE COMPREENDE DOIS SUBSISTEMAS: UM PRIMEIRO SUBSISTEMA DE AVALIAÇÃO DA ABRANGÊNCIA DA INOVAÇÃO, QUE CATEGORIZA A INOVAÇÃO DE ACORDO COM O NÍVEL DE NOVIDADE EM ESCALAS GEOGRÁFICAS; E UM SEGUNDO SUBSISTEMA QUE CATEGORIZA A INOVAÇÃO DE ACORDO COM QUATRO FATORES DE INFLUÊNCIA (GRAU DA INOVAÇÃO, NATUREZA DAS ATIVIDADES REALIZADAS, ENGAJAMENTO E BARREIRAS TECNOLÓGICAS). O SISTEMA DA INVENÇÃO PROPORCIONA ELEMENTOS OBJETIVOS E QUANTITATIVOS PARA UMA AVALIAÇÃO PRECISA SOBRE FRAGILIDADES E BENEFÍCIOS DE CADA PROJETO. DESSA FORMA, TRATA-SE DE UMA FERRAMENTA A SER APLICADA DIRETAMENTE NAS ESTRATÉGIAS PARA MINIMIZAÇÃO DOS RISCOS INERENTES ÀS INICIATIVAS INOVADORAS, O ELEMENTO CENTRAL DOS SISTEMAS DE GESTÃO DA INOVAÇÃO.
Patent RU-94013037-A (RU)
Inventor: MOVCHANJUK V M
IPC: B05D1/00
Filed: 1994-04-12
Abstract: FIELD: civil engineering, may be used for treating walls and foundations of buildings with water-repellent liquids. SUBSTANCE: elastic oscillations are generated with frequency of foundation material concurrently with injecting water-repellent liquids into holes drilled for 7 - 8 cm depth with spacing 150 - 250 mm. Complete treatment of the foundation is achieved for 20 30 minutes using elastic oscillation. EFFECT: elimination of ground water rise through capillaries. 6 cl, 1 dwg
Patent RU-94025008-A (RU)
Inventor: ZHELIGOVSKAJA N N
IPC: A61P35/00
Filed: 1994-07-08
Abstract: FIELD: pharmacy. SUBSTANCE: antitumor agent has cis-diamminedichlorodihydroxoplatinum (IV) as compound of platinum (IV) at concentration 10-25%, sodium hydrocarbonate at concentration 25-55%, and sodium alginate at concentration 40-60%. Antitumor agent containing cis-diamminedichlorodihydroxoplatinum (IV) shows activity at oral administration, nephrotoxicity absence, metastasis growth inhibition, high broad of therapeutic action spectrum. Agent can be used for treatment leukemia, adenocarcinoma, uterus cervix cancer, melanoma, sarcoma, Lewis carcinoma, hepatoma and other oncological diseases. EFFECT: enhanced effectiveness of agent.
Patent RU-94028395-A (RU)
Inventor: POLUKHIN V N
IPC: C03B37/10
Filed: 1994-07-22
Abstract: FIELD: optoelectronic engineering, glass technology, optical converters, and cathode-ray tubes. SUBSTANCE: for producing microchannel plate, channel fiber is drawn out of thermoplastic material, agglomerated into block with parallel channels which is mechanically treated to produce blank in the form of prismatic plate or straight cylinder with acute angles between channels axis and height not exceeding 17 deg., secured within mold embracing the blank, and channels are curved to set up inertia force within blank acting on blank mass in thermoplastic state in direction perpendicular to its height. EFFECT: enlarged functional capabilities.
Patent RU-94030067-A (RU)
Inventor: SANNIKOV JU N
IPC: A47C3/18
Filed: 1994-08-05
Abstract: FIELD: production of stools with single central support. SUBSTANCE: furniture article has carrier surface, vertical support and upper supporting unit composed of horizontal crossed connecting strips which are engageable to define slot for receiving retaining member. Furniture article is further provided with lower supporting unit attached to lower part of vertical support. Each supporting unit is composed of crossed horizontal connecting strips with central projections, whose inner surfaces define slot. Ends of vertical support are used as retaining members for upper and lower supporting units. Upper end of support is provided with shaped groove extending along perimeter of support end, with groove height being equal to that of connecting strip. Furniture article may be used in toy furniture sets and may be made from wood, preferably hard wood, as well as from plastic or metal material. EFFECT: simplified production and assembling process, improved quality, wider operational capabilities and enhanced reliability in operation. 3 cl
Patent RU-94037011-A (RU)
Inventor: SHKANOV O V
IPC: G07C3/00
Filed: 1994-10-03
Abstract: FIELD: automation and computer engineering. SUBSTANCE: device has primary transducer, which has detector, for example of temperature, analog-to-digital converter, first, second and third registers, read- only memory unit, dividing unit, multiplication unit, adder, subtraction unit, first, second, third, fourth and fifth comparison circuits, unit which generates increment of depleted resource part, control unit, first and second switches, memory unit, unit for setting of extreme permissible levels of characteristics, mode switch unit, unit for switching protection units, unit which generates signal that object operates under condition of limited resources, reserve switching unit, power clipping unit and unit for switching object off. Mode switching unit selects one of two modes: resource detection mode and mode for detection of extreme permissible levels of monitored characteristics. Resource level for current state is calculated in first mode by means of signals which are proportional to monitored characteristic of power production object. Rest of resource is calculated according to variable level of coefficient of depleted part of resource. When device is started, depleted part of resource is increased by level which is used at start. Then depleted part of resource is increased in real time conditions for stationary modes and calculated anew during each switch to new mode. Sequence of values of monitored characteristics which runs from zero to extreme permissible level is generated in second mode by unit for detection of extreme permissible levels of monitored characteristics. Level at which rest of resource reaches given level for protection of monitored power object is detected in memory unit and is shown on display. Then device is switched to first mode. EFFECT: increased functional capabilities due to calculation of state of power production object and detection of current extreme permissible level of monitored parameter.
Patent RU-94039820-A (RU)
Inventor: MODEEV V F
IPC: B21B45/04
Filed: 1994-10-24
Abstract: FIELD: rolled stock production, namely finishing descaler of wide strip hot rolling mills arranged behind flying shears of group of finishing stands of mill. SUBSTANCE: descaler includes struts, upper and lower feeding rollers with chocks mounted in ports of said struts; cross beam joining said struts and pneumatic cylinders for moving upper roller mounted on said cross beam. Chocks of upper roller are mutually connected by timing device in the form of axle. Said axle is arranged in parallel with rollers in bearings and has two levers rigidly secured to its ends. Said levers are jointly connected with chocks of upper roller by means of pins secured to chocks and placed in lengthwise grooves of said levers. EFFECT: enhanced quality of strip descaling, high reliability of descaler.
Patent RU-94040129-A (RU)
Inventor: OLEJNIKOV V E
IPC: B22C1/22
Filed: 1994-10-27
Abstract: FIELD: foundry. SUBSTANCE: hardener based on aluminium chloride aqueous solution is supplemented with 1.0-1.6 wt % ammonium citrate, which results in 1.28-1.44 times diminishing brittleness of cores. EFFECT: increased strength of cores. 2 tbl
Patent RU-94040162-A (RU)
Inventor: ZIGMUNT MARIAN ANDREVSKI
IPC: H01J9/20
Filed: 1994-11-02
Abstract: FIELD: television engineering. SUBSTANCE: color tube has shadow mask placed at viewing screen. Mask has shaped section with holes and peripheral skirt. Novelty is that skirt is inversely bent; its first part connected to shaped perforated section is directed away from screen and second part most distant from shaped perforated section, faces screen. EFFECT: improved design of shadow mask.
Patent RU-94040304-A (RU)
Inventor: SLOBODJANIK I P
IPC: C12H1/22
Filed: 1994-11-01
Abstract: FIELD: production of cognac-type beverages. SUBSTANCE: oak staves 10 mm thick are loaded into coated vessels into which alcohol is then poured in followed by keeping alcohol in contact with oak staves under periodically increased pressure owing to feeding compressed air from air bottle through bubbler into lower section of vessel under oak staves. After specified period of time, pressure is reduced to its normal value. Excess pressure value ranges from 2 to 5 atm, and period of keeping alcohol under excess pressure is 24-28 h. Period of keeping alcohol under normal pressure is the same. Number of pressure increase-decrease cycles depends on chosen excess pressure value, duration of the cycle, and organoleptic attributes of sampled cognac-type alcohol. EFFECT: enhanced efficiency of process.
Patent RU-94041517-A (RU)
Inventor: DOLGIKH V A
IPC: C01B17/04
Filed: 1994-11-16
Abstract: FIELD: methods of hydrogen sulfide disintegration used for gas purification from hydrogen sulfide. SUBSTANCE: aim is to increase output of photodissociation of hydrogen sulfide, effective disintegration of hydrogen sulfide in mixture with natural gas. Aim is realized by additional introduction in gas mixture composition of at least one component from group: oxygen, ozone, dry atmospheric air with following irradiation carried out by emission with photons energy exceeding threshold of oxygen-bearing molecule photodissociation. Ozone or mixture of ozone with dry atmospheric air or oxygen is added in composition of gas mixture, that is bearing HS and irradiation is carried out by emission with photons energy exceeding threshold of photodissociation. Irradiation of mixture of hydrogen sulfide with natural gas is carried out by emission with photons energy less than threshold of photodissociation. EFFECT: increased effectiveness of hydrogen sulfides dissociation.
Patent RU-94045473-A (RU)
Inventor: BOGOSLOVSKIJ S I
IPC: F02M25/10
Filed: 1994-12-28
Abstract: FIELD: mechanical engineering; internal combustion engine fuel system. SUBSTANCE: method comes to delivery of fuel-air mixture into cylinders with preliminary enrichment of air by ozone. Air enrichment with ozone is carried out at all operating duties. Concentration of ozone in air stream is 10-1.0% of amount of air. System for implementing the method has air duct 1, filter 2 with filtering element 3 and ozone generator 4 connected to storage battery and playing the part of barrier electric spark gap. Ozone generator 4 is installed after filtering element 3 in direction of air flow. EFFECT: improved combustion of fuel.
Patent RU-94046160-A (RU)
Inventor: DZHON MARTIN GREJG
IPC: B29L9/00
Filed: 1994-03-31
Abstract: FIELD: treatment of polymer materials. SUBSTANCE: polyethylene pipe is reinforced by two layers of polyethylene belt wound around pipe in opposite directions under tension. Composition of pipe includes carbon black, layers are not pigmented, have no additives and are transparent for IR radiation to which first main surface is subjected. Radiation is in nearest region of IR range and predominant part of radiated energy has wave length not less than 2.5 μm Layers absorb very small portion of radiation, its bigger portion is absorbed by outer surface of pipe. Thanks to this separation boundaries between second main surface of layer and first main surface of pipe as well as between second main surface of layer and first main surface of layer are heated to temperature at which layers interfused and welded by fusion to pipe. EFFECT: enhanced reliability of connection.
Patent RU-95100354-A (RU)
Inventor: SHATALOV V V
IPC: C07C17/389
Filed: 1995-01-11
Abstract: FIELD: purification and stabilization of ethane and propane coolants. SUBSTANCE: ampholites of special purpose based on vinyl pyridine and having specific characteristics during absorption of halogen substituted aliphatic acids and anhydrides thereof are used for the first time for purification of coolants from impurities. The claimed process makes it possible to purify coolant from impurities in single stage and to used sorbent in repeated sorption- regeneration cycles. Coolants purified by amphalites withstand "mirror" test become stable and remain viable when exposed to light for lengthy period of time (more than 6 months). EFFECT: more efficient sorption purification process.
Patent RU-95102682-A (RU)
Inventor: KOKORIN O A
IPC: E04H6/14
Filed: 1995-02-28
Abstract: FIELD: garages and car parks. SUBSTANCE: guide for each pulling chain of the conveyor is made in the form of single frame equipped with shaped beam, supports for installing conveyor sprockets and cantilevers for fastening the frame to the bearing case of the garage. Pulling chain is made as crawled with links and non-full- swing connecting hinges and equipped with U-shaped traverses with lateral sides. Support rollers are installed on the sides. Platform suspension cantilevers are secured to the traverse. EFFECT: enhanced reliability and safety in both normal operation and accidents due to breaking pulling chain. 1 cl
Patent RU-95102922-A (RU)
Inventor: KSAB ER RUIS DEL PORTAL
IPC: H02J13/00
Filed: 1995-02-27
Abstract: FIELD: counters concentrators. SUBSTANCE: counters concentrator in transformation center for consumption remote control system, in which indicator of consumption and auxiliary concentrators of counters using electrical line of low voltage are connected with main concentrators of counters and in this connection main concentrator is provided with modem to transfer data in low voltage electric line and is fed by the line and also has detector of faults and phase selection and is connected with computer of higher order by channel of telephone communication and with potable reading device. For the purpose it has infra-red beams interface and memory unit and is controlled by microprocessor. EFFECT: improved design.
Patent RU-95103687-A (RU)
Inventor: VETER V V
IPC: B23K35/40
Filed: 1995-03-13
Abstract: FIELD: welding; calcination of welding fluxes at their manufacture and in use. SUBSTANCE: temperature and duration of process depend on flux basicity and are calculated by formulas: T=211+308 ln(1+$$$); $$$, where T - calcination temperature, C; $$$ - calcination time, h; $$$ - flux basicity. EFFECT: provision of complete evacuation of moisture from flux without overheating and no adverse effect on flux welding properties.
Patent RU-95104850-A (RU)
Title: Method of production of steel-based monoplates
Inventor: KONDRASHIN JU A
IPC: B41N1/08
Filed: 1995-04-04
Abstract: FIELD: printing; offset printing. SUBSTANCE: the method offers production of monoplates on sheet metal, particular, on sheet steel. Monoplates are produced with the use of the known sheet-galvanizing line. Sheet is, first, degreased, then the surface is subjected to chemical activation and electrochemical chrome plating in bichromate electrolyte, dried, and light-sensitive layer is applied. EFFECT: higher efficiency.
Patent RU-95112131-A (RU)
Inventor: IBRAGIMOV N G
IPC: C08L59/02
Filed: 1995-07-12
Abstract: FIELD: fuels. SUBSTANCE: invention proposes original complex modifying agent of combustion involving polyhydroxymethylene, octogen and combustion catalyst. The use of this agent in combination with other components of ballistite fuel ensures to increase the index of combustion velocity dependence from pressure from 0.4-0.5 to 0.9 and above. EFFECT: enhanced effectiveness of agent.
Patent TW-200301178-A (TW)
Title: Method and apparatus for endpoint detection during chemical mechanical polishing
Inventor: PARIKH PRABODH J
IPC: B24B37/04
Filed: 2002-11-08
Abstract: An apparatus for in situ CMP endpoint detection is presented which includes a probe member for emitting and receiving light signals, a transparent plug mounted over the end of the probe, and a support member located about, and slidably engaged with, the outer circumference of the probe. In use, the plug is inserted into an opening in a polishing pad so that the top of the plug is recessed or coplanar with respect to the polishing surface of the pad and the support member is inserted into an opening in a platen such that a seal is formed between the platen and the support member. The probe member, plug, and/or support member may be disposable and replaceable either alone or in combination.