Patent SG-11201805374R-A (SG)
Title: Intradermal jet injection electroporation device
Inventor: MCCOY JAY
IPC: A61M5/24
Filed: 2016-12-28
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 6 July 2017 (06.07.2017) WIPOIPCT (10) International Publication Number WO 2017/117273 A1 (51) International Patent Classification: A61B 5/00 (2006.01) A61M 5/20 (2006.01) A61B 17/20 (2006.01) A61M 5/24 (2006.01) A61K 9/00 (2006.01) A61M 5/315 (2006.01) A61M 5/172 (2006.01) (21) International Application Number: PCT/US2016/068972 (22) International Filing Date: (25) Filing Language: (26) Publication Language: 28 December 2016 (28.12.2016) English English (30) Priority Data: 62/271,969 28 December 2015 (28.12.2015) US (71) Applicant: INOVIO PHARMACEUTICALS, INC. [US/US]; 660 W. Germantown Pike, Suite 110, Plymounth Meeting, PA 19462 (US). (72) Inventors: MCCOY, Jay; c/o Inovio Pharmaceuticals, Inc., 660 W. Germantown Pike, Suite 110, Plymouth Meet­ ing, PA 19462 (US). BRODERICK, Kate; c/o Inovio Pharmaceuticals, Inc., 660 W. Germantown Pike, Suite 110, Plymouth Meeting, PA 19462 (US). KEMMERRER, Stephen; c/o Inovio Pharmaceuticals, Inc., 660 W. Ger­ mantown Pike, Suite 110, Plymouth Meeting, PA 19462 (US). (74) Agent: HOFMEISTER, Todd, S.; Michael Best & Friedrich LLP, 100 East Wisconsin Avenue, Suite 3300, Milwaukee, WI 53202 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, [Continued on next page] (54) Title: INTRADERMAL JET INJECTION ELECTROPORATION DEVICE l> CJ l> 47 43 O CJ (57) : An jet injection and electroporation device for use with an agent cartridge defining a volume containing a pre-meas - ured dose of agent therein, the electroporation device including a housing having an axis extend therethrough, a nozzle at least par­ tially positioned within the housing, and a cavity sized to receive at least a portion of the agent cartridge therein. The device also in - eludes an array having a plurality of electrodes extending therefrom, a propulsion cartridge configured to operatively engage the cartridge when the agent cartridge is positioned within the cavity; and a power supply in electrical communication with the array. WO 2017/117273 A11II llll IIII III Hill III III III III fill 111 II 111 lllll 111 mill llll 111 llll TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, Published: TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, ~ Wlth ^national search report (Art. 21(3)) LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).