baber/WOPTO huggingface dataset:
Patent ES-2421538-T3 (ES)
Title: Proteasas no pancreáticas para controlar la concentración de colecistocinina (CCK) en plasma y para tratar el dolor
Inventor: MARGOLIN ALEXEY L
IPC: A61K38/48
Filed: 2004-10-29
Granted: 2013-09-03
Abstract: Una proteasa no pancreática seleccionada del grupo que consiste en seaprosa, pronasa y serrapeptasa parasu uso en el tratamiento de dolor abdominal asociado con insuficiencia pancreática, pancreatitis aguda,fibrosis quística o cirugía gastrointestinal posoperatoria; dolor abdominal asociado con enfermedades ytrastornos gastrointestinales seleccionados del grupo de malabsorción de proteínas (azotorrea), malabsorciónde lípidos (esteatorrea), diabetes mellitus, enfermedades ulcerosas y combinaciones de las mismas; dolorabdominal asociado con cólico biliar, colecistitis, colecistitis ascendente, colelitiasis, adicciones narcóticas,disfunción del esfínter de Oddi, vaciado gástrico retrasado o daño por quimioterapia, o dolor abdominalasociado con anorexia en un mamífero.
Patent ES-2285554-T3 (ES)
Inventor: DIAZ PHILIPPE
IPC: C07D403/06
Filed: 2004-12-08
Granted: 2007-11-16
Abstract: Novel compounds that are modulators of PPAR-type receptors having the structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and in the field of cardiovascular diseases, immune diseases and/or diseases linked to the metabolism of lipids), or, alternatively, into cosmetic compositions.
Patent ES-2298903-T3 (ES)
Inventor: HAHN HORST
IPC: B21C37/12
Filed: 2005-10-06
Granted: 2008-05-16
Abstract: Production of flexible internally smooth corrugated tube with an inner smooth metal band (4) of the same width as the outer bent metal band (2). The corrugated tube has a bent groove (16) passing along the center. Independent claims are included for: (1) a device for carrying out the process; (2) a corrugated tube with an inner band in stainless steel.
Patent ES-2360534-T3 (ES)
Title: Sistema de afeitado.
Inventor: WORRICK CHARLES
IPC: B26B21/22
Filed: 2005-03-03
Granted: 2011-06-06
Abstract: Una máquina de afeitar (10) que incluye un cartucho (12) y un mango (14), comprendiendo la máquina de afeitar: una carcasa (20) de cartucho que tiene un borde delantero (44), un borde trasero (46) y dos bordes laterales que se extienden desde el borde frontal hasta el borde trasero; una o más hojas de afeitar entre el borde delantero y el borde trasero de la carcasa de cartucho; caracterizado por que dicha máquina de afeitar además comprende un elemento conector (18) conectado a la carcasa de cartucho y que incluye un elemento flexionable que define al menos una parte de una abertura (178) que se extiende a través del elemento conector; y el mango incluyendo un elemento de interconexión del mango que incluye un saliente (166) que tiene un extremo distal (180) alargado y superficies laterales (182, 184) en ángulo que se extienden desde el extremo distal hasta una base (186) relativamente más pequeña, el extremo distal alargado del saliente teniendo una dimensión mayor que una dimensión de la abertura, de tal manera que la inserción del saliente en la abertura flexiona el elemento flexionable para fijar el elemento conector al elemento de interconexión del mango.
Patent ES-2427169-T3 (ES)
Title: Aparato para producción farmacéutica
Inventor: CLARKE ALLAN J
IPC: B67B7/00
Filed: 2005-06-09
Granted: 2013-10-29
Abstract: Un aparato (10) para producir una pluralidad de productos (3.000) farmacéuticos, que tienen cada uno uncomprimido (1.000) portador y una dosis de un agente (2.000) farmacéutico activo, comprendiendo el aparato (10):un módulo (420) de distribución que distribuye la dosis de un agente (2.000) farmacéutico activo sobre cadauno de, el comprimido (1.000) portador, en el que la dosis de un agente (2.000) farmacéutico activo es unagota (2.100) líquida; un miembro (200) de sujeción que soporta los comprimidos (1.000) portadores y un transportador (300) para mover dicho miembro (200) de sujeción por el aparato (10), caracterizado por que dicho módulo (420) de distribución se mueve con respecto a cada uno de loscomprimidos (1.000) portadores y dicho miembro (200) de sujeción en una dirección transversal altransportador (300) a medida que distribuye la dosis (2.000) y dicho miembro (200) de sujeción se mueve de manera continua por el transportador (300) a medida quedicho módulo (420) de distribución distribuye la dosis (2.000).
Patent ES-2330768-T3 (ES)
Inventor: BAECKE MARTIN
IPC: F04D23/00
Filed: 2005-10-05
Granted: 2009-12-15
Abstract: The invention relates to a side channel compressor, comprising a housing shell and a running wheel. The running wheel is mounted to be rotatable with respect to the housing shell to provide two annular sealing areas between the housing shell and the running wheel. The housing shell between the first and the second sealing area can be made of one piece. The gap dimensions of the first and second sealing areas can be adjusted by means of a disc spring/nut system or a wobble means. A fan impeller may be fixed on the motor shaft, and the housing shell can comprise cooling ribs, wherein the cooling ribs are arranged and formed such that the air conveyed by the fan impeller sweeps through the cooling ribs. One of the annular sealing areas can include a dead volume chamber. The housing shell may be a casting or a machined extruded profile.
Patent ES-2456017-T3 (ES)
Title: Tratamiento del cáncer con una combinación de un agente que perturba la ruta de señalización de EGF y un oligonucleótido que reduce los niveles de clusterina
Inventor: GLEAVE MARTIN
IPC: A61K31/7088
Filed: 2005-11-22
Granted: 2014-04-21
Abstract: Una combinación para tratar el cáncer en un sujeto mamífero, que comprende (i) un agente que es eficaz para el tratamiento del cáncer en el sujeto mamífero, y perturba la ruta de señalización celular de HER-2 pero incrementa el nivel de expresión de clusterina, siendo el agente un anticuerpo monoclonal específico para HER-2, un inhibidor de molécula pequeña de HER-2, un péptido o peptidomimético capaz de interferir con HER-2, o un oligonucleótido antisentido anti-HER-2, y (ii) un oligonucleótido antisentido o una molécula inductora de la interferencia del ARN, induciendo dicho oligonucleótido o molécula inductora de la interferencia del ARN el redireccionamiento del ARNm de clusterina y comprendiendo nucleótidos en una secuencia que es complementaria al ARNm de clusterina, y siendo adicionalmente eficaz para reducir la cantidad eficaz de clusterina en una célula cancerosa.
Patent ES-2297775-T3 (ES)
Inventor: MACKIEWICZ JOHN EDMUND
IPC: F16D65/095
Filed: 2006-02-17
Granted: 2008-05-01
Abstract: A disc brake (10) has an anchor (12) that is fixed to a housing (14) to align first (31) and second (33) rails and friction pads (36,40) for each of first (30) and second (32) friction members with radial surfaces (42a,42b) on a rotor (42). The friction pads (36,40) are respectively moved into engagement with radial surfaces (42a,42b) by an actuation force to develop a brake force and resulting reaction forces that are carried into the anchor (12) to oppose the rotation of the rotor (42) during a brake application. The anchor (12) has projections (70, 72) on the first rail (31) located in planes that are offset from radial engagement surfaces (42a, 42b) on the rotor (42). The friction members (36, 40) each have a carrier 34, 38) with an outwardly projecting lip (34a, 38a) on a first end through which the brake forces are transmitted into the projections (70, 72). Since the projections (70, 72) are offset, a moment is created by the reactions forces and as a result an axial component thereof is added to the actuation force during a brake application.
Patent ES-2321540-T3 (ES)
Title: Pastilla de oxido de combustible nuclear y procedimiento de fabricacion correspondiente.
Inventor: DELAFOY CHRISTINE
IPC: G21C3/62
Filed: 2001-11-27
Granted: 2009-06-08
Abstract: Pastilla (10) sinterizada de óxido de combustible nuclear, siendo la pastilla sensiblemente cilíndrica y a base de óxido de uranio enriquecido, caracterizada porque comprende entre 1200 ppm y 1750 ppm en masa de Cr2O3, que no se ha reducido durante la sinterización de la pastilla.
Patent ES-2326992-T3 (ES)
Inventor: GRUNERT JORN
IPC: H04L12/14
Filed: 2006-09-08
Granted: 2009-10-22
Abstract: The method involves registering a subscriber terminal over a network in a central system using a user account and storing network connections, addressing, services and quality of services in the terminal. A quality profile is configured based on a destination address or a connection between an end terminal and the subscriber terminal during an outgoing communication. Types of network communications of the terminals are included to configure a connection corresponding to the profile. The profile is determined based on a source address of a source terminal during incoming communication. Independent claims are also included for the following: (1) a device for controlling incoming and outgoing communication connections between subscriber terminals with a network terminal (2) a terminal that is registered in a central server system.
Patent ES-2312130-T3 (ES)
Inventor: JAHN STEFFEN
IPC: F01P3/20
Filed: 2006-03-20
Granted: 2009-02-16
Abstract: The invention is directed to a cooling system for an internal combustion engine of a vehicle to a vehicle comprising such a cooling system, and to a method for cooling an internal combustion engine of a vehicle, in particular a diesel railcar. The cooling system has a first cooling liquid passage 1 for conveying cooling liquid flowing from a cooling liquid outlet of said internal combustion engine 3 to an inlet of a radiator device 4, a second cooling liquid passage 2 for conveying cooling liquid from an outlet of said radiator device to an cooling liquid inlet of said internal combustion engine 3, and a heat accumulator 15 connected to the first cooling liquid passage. According to the invention the cooling system is relieved of heat load peaks by taking up heat peaks of the cooling liquid with the heat accumulator 15 during high heat load periods of the cooling system and by discharging the heat accumulator 15 during low heat load periods by transferring heat stored in the heat accumulator 15 to the cooling system and/or a heating system connected thereto.
Patent ES-2386974-T3 (ES)
Title: Formas cristalinas de la 4-metil-N-[3-(4-metil-imidazol-1-il)-5-trifluoro-metil-fenil]-3-(4-piridin-3-il-pirimidin-2-il-amino)-benzamida
Inventor: MANLEY PAUL
IPC: A61K31/506
Filed: 2006-07-18
Granted: 2012-09-10
Abstract: Una forma cristalina A sustancialmente pura de la sal de clorhidrato de 4-metil-N-[3-(4-metil-imidazol-1-il)-5-trifluoro-metil-fenil]-3-(4-piridin-3-il-pirimidin-2-il-amino)-benzamida que se caracteriza por un patrón dedifracción en polvo de rayos-X que tiene cuando menos un máximo seleccionado a partir deaproximadamente 8.5°, 11.0°, 11.5°, 17.2°, 18.8°, 19.2°, 20.8°, 22.1°, y 26.0º (grados 2θ); donde"sustancialmente pura" significa que más del 50% de las sal de clorhidrato de 4-metil-N-[3-(4-metil-imidazol-1-il)-5-trifluoro-metil-fenil]-3-(4-piridin-3-il-pirimidin-2-il-amino)-benzamida está presente en dicha formacristalina.
Patent ES-2380505-T3 (ES)
Inventor: ABBA FABIENNE
IPC: A61L15/58
Filed: 2006-10-10
Granted: 2012-05-14
Abstract: A hot melt adhesive composition, comprising a blend of components including about 10% to about 40% by weight of an elastomeric block copolymer, preferably styrene-isoprene-styrene (SIS) or styrene-butadiene-styrene (SBS), about 15% to about 70% by weight of a first midblock tackifying resin having a softening point of at least about 110° C. and having an aromatic content of at least about 1.5% by weight; about 0 to 55% of second midblock tackifying resin, about 5% to about 35% by weight of a plasticizer; and about 0% to about 20% by weight of an end block resin having a softening point lower than 125° C.; wherein the components total 100% by weight of the composition, the viscosity of the composition is equal to or less than about 20,000 mPa·s at 120° C., and is applied at a temperature lower that 150° C. and initial bond retention of the composition on elastic strands is at least about 60%. Also, the elastic modulus G′ of the composition is higher than about 5000 Pa, the vicous modules G″ is higher than about 50 Pa, and the tan delta value is between about 0.5 and about 60. Laminates, especially those used in disposable soft goods, and methods of making such laminates are also described. The adhesive composition and/or laminate may be used in making a variety of end products such as a disposable diaper, a sanitary napkin, a bed pad, a bandage, a surgical drape, a tape, a label, a plastic sheet, a nonwoven sheet, a paper sheet, a cardboard, a book, a filter, or a package.
Patent ES-2336263-T3 (ES)
Inventor: WEGENER DIRK
IPC: A47L15/50
Filed: 2007-07-31
Granted: 2010-04-09
Abstract: The dishwasher appliance (1) has one or more movable baskets (4), within a housing (2). At least one basket has rollers (5) on both sides riding on rails (6) set at an adjustable angle by ramps (8), for the basket to run out of the interior (3) automatically when the door (7) is opened.
Patent ES-2333370-T3 (ES)
Inventor: SCHUMANN DR UWE
IPC: C08G18/22
Filed: 2007-04-12
Granted: 2010-02-19
Abstract: Contact adhesive based on a polyurethane obtained by reacting aliphatic or alicyclic polyisocyanate with a functionality of not more than 3 with a combination of polypropylene glycol-based triols with mol. wts. (Mn) of not more than 1000 (triol A) and at least 1000 (preferably at least 3000) (triol B) respectively, using an NCO/OH ratio of 0.8-1.15 (preferably 0.95-1.05) and an OH group ratio (A/B) of up to 12, with an organic bismuth compound as catalyst, preferably a bismuth carboxylate. Polyurethane-based pressure-sensitive adhesive (I), in which the polyurethane is obtained by reacting (a) aliphatic or alicyclic polyisocyanate(s) with a functionality of not more than 3 with (b) a combination of polypropylene glycol-based triols (A) and (B) with number-average mol. wts. (Mn) of not more than 1000 and at least 1000 (preferably at least 3000) respectively, where the ratio of OH groups in (A) to those in (B) = between more than 0 and 12, the ratio of NCO groups to total OH groups = 0.8-1.15, preferably 0.95-1.05, and the catalyst is or contains an organic bismuth compound, preferably a bismuth carboxylate or derivative thereof. An independent claim is included for a method for the production of (I) by (a) placing the premixed triols and the isocyanate component in separate tanks (with other ingredients as required), feeding the polyol and isocyanate components through the mixing head or mixing tube of a multi-component mixing/metering unit by means of a precision pump, transferring the reacting mixture immediately to a belt of carrier material (preferably moving at constant speed), hardening the polyurethane in a heating channel and then winding the coated material into a roll.
Patent ES-2354477-T3 (ES)
Inventor: HANSSEN HUBERT JOSEPH FRANS
IPC: B65D47/24
Filed: 2007-05-30
Granted: 2011-03-15
Abstract: The invention relates to a closing valve (1) for a container for a fluid, comprising an outer jacket (6) connected or connectable to an opening (3) in the container or forming part of the container, an inner jacket (8) accommodated inside the outer jacket (6) and having an opening (9) through which the fluid can be fed to or withdrawn from the container, and a closing element (10) positioned inside the inner jacket (8) or between the inner jacket (8) and the outer jacket (6) and movable between at least a first position closing the opening and a second position clearing the opening (9), wherein at least the closing element (10) is made from a polymer material. The closing element (10) comprises a sealing member (30) and a spring (32), which urges the closing element (10) into the first position.
Patent ES-2352430-T3 (ES)
Title: Cartucho de varios componentes.
Inventor: HEUSSER ROLF
IPC: A61C5/64
Filed: 2007-09-07
Granted: 2011-02-18
Abstract: Cartucho de varios componentes con un depósito (1), que presenta cámaras (2, 3) para el alojamiento de diferentes componentes fluidos, en el que en el extremo de salida del depósito se proporciona una zona de dispensación (9), prolongando la zona de dispensación (9) las cámaras (2, 3) con forma de canal hacia las aberturas de dispensación (2', 3') en su extremo superior, pudiéndose dispensar los componentes a través de las aberturas de dispensación (2', 3') desde las cámaras (2, 3) a una cámara de mezcla (10, 10'), estando rodeada la cámara de mezcla por un elemento mezclador estático (8) dispuesto firmemente en el depósito (1) para la mezcla de los componentes y un tubo de descarga (5) aplicado en el elemento mezclador estático (8) y que se puede unir con el depósito (1) para la descarga de los componentes, si el tubo de descarga (5) está en su posición abierta, estando configurado el elemento mezclador estático (8) como elemento de guía para el desplazamiento axial del tubo de descarga (5) y proporcionándose elementos de seguridad (7, 7') en el depósito (1) y/o en el tubo de descarga (5) para evitar una retirada del tubo de descarga (5) del depósito (1) y siendo el contorno exterior del elemento mezclador estático (8) y el contorno interior del tubo de descarga (5) rectangulares o elípticos.
Patent ES-2344159-T3 (ES)
Inventor: BERTOZZI FRANCO
IPC: B62D35/00
Filed: 2007-09-26
Granted: 2010-08-19
Abstract: A system is described for controlling and managing the actions of inflation and deflation of inflatable spoilers made up of sub-systems, said system being able to monitor variations in the speed of the vehicle as this increases and decreases, and to generate one or more independent "inflation" signals and one or more independent "deflation" signals, to be sent to one or more of said inflatable spoiler sub-systems, upon reaching vehicle speed thresholds, for "inflation" and "deflation" respectively, said speed thresholds for "inflation" being higher than said speed thresholds for "deflation".
Patent ES-2337200-T3 (ES)
Inventor: CHEVAL PATRICE
IPC: A47F5/11
Filed: 2007-09-11
Granted: 2010-04-21
Abstract: The device has a rectangular shaped base (2) with median and lateral elongated openings (6, 7) that are situated at a distance from each other. A spacer (4) includes a portion (11) forming a clean spacer connected to a sign panel (3). The spacer has an extension (12), which is not connected to the panel, extending the portion from a side of the base, where the extension is folded with respect to the portion. The extension is engaged through the opening (6), folded against the base, and is engaged through the opening (7) by slight deformation to lock the extension in unfolding position.
Patent ES-2632642-T3 (ES)
Title: Agentes repelentes de plagas que comprenden geranilacetona
Inventor: PICKETT JOHN ANTHONY
IPC: A01P17/00
Filed: 2007-03-02
Granted: 2017-09-14
Abstract: Una composición que comprende geranilacetona como principio activo más un principio activo adicional que es la 6-metil-hepten-2-ona, en donde la 6-metil-5-hepten-2-ona y la geranilacetona están presentes en una proporción en peso de aproximadamente 1:1.
Patent ES-2402072-T3 (ES)
Title: Composición de glaseado tixotrópico gelificante en frío
Inventor: CELHAY FREDERIC
IPC: A23L29/00
Filed: 2007-02-08
Granted: 2013-04-26
Abstract: Composición de glaseado tixotrópico gelificado en frío que tiene un valor Brix en el intervalo de 20-65; que contiene almenos 0,1% en peso y menos de 2,5% en peso de pectina débilmente metoxilada-amidada (LMA) con un grado demetoxilación de 15-35% y un grado de amidación de 15-30%; y que contiene al menos 34% en peso de agua, donde losmono- y/o disacáridos representan al menos 90% en peso de la cantidad total del material de carbohidratos quecontiene la composición de glaseado, sin incluir pectina LMA, donde los disacáridos representan al menos 50% en pesodel material de carbohidratos que contiene la composición de glaseado, sin incluir pectina LMA; y donde dichacomposición, después de haber sido cortada suficientemente para hacerse vertible, forma un gel con una resistencia degel de al menos 10 g cuando se deja en reposo durante 60 minutos en condiciones inertes a una temperatura de 6 °C.
Patent ES-2561159-T3 (ES)
Title: Cánula con una carcasa protectora
Inventor: SARSTEDT WALTER
IPC: A61M5/32
Filed: 2007-03-16
Granted: 2016-02-24
Abstract: Cánula, de forma preferida con un soporte de cánula (1) en particular para un disposición de extracción de sangre, que presenta una carcasa protectora (102) basculante, cerrada perimétricamente excepto por una abertura de entrada de cánula (8) prevista entre paredes laterales (7a, 7b) mutuamente opuestas, proporcionada por al menos una pareja de laminillas (8a, 8b), conformada sobre las paredes laterales (7a, 7b), que converge hacia dentro en forma de tolva y allí forma una rendija de tolva (S) ensanchable, para un extremo de cánula libre (4a), caracterizada porque la carcasa protectora (102) se compone de dos partes de carcasa enchufadas concéntricamente una dentro de la otra, en donde una carcasa interior (2a) presenta la pareja de laminillas (8a, 8b) y una carcasa exterior (11) que abraza la carcasa interior (2a) está configurada como un manguito menos elástico con relación a la carcasa interior (2a).
Patent ES-2376364-T3 (ES)
Inventor: DUBOIS JEAN-LUC
IPC: C07C29/60
Filed: 2007-02-06
Granted: 2012-03-13
Abstract: The invention relates to a method for preparing acrolein from propylene, consisting of a first glycerol dehydration step preformed in the presence of a gas containing propylene and, more specifically, in the presence of the reaction gas originating from the propylene to acrolein oxidation step. The inventive method enables the use, in part, of renewable raw material, while increasing acrolein production.
Patent ES-2392996-T3 (ES)
Title: Procedimiento para la preparación de derivados de pirazolilaminoquinazolina que contienen un grupo fosfato
Inventor: PITTAM JOHN
IPC: C07F9/02
Filed: 2007-05-14
Granted: 2012-12-17
Abstract: Un proceso para preparar un compuesto intermedio de fórmula (II)fórmula (II)en la cual A es un heteroarilo de miembros que contiene un átomo de nitrógeno y que contiene opcionalmente 1, 2ó 3 átomos de nitrógeno adicionales;X es -NH- o -N(C1-4 alquilo)-;m es 0, 1, 2 ó 3;R1 es C1-6 alquilo sustituido con -OP(O)(OH)(OR) y sustituido opcionalmente además con 1 ó 2 grupos C1-4 alcoxi;R2 es hidrógeno o C1-6 alquilo sustituido opcionalmente con 1, 2 ó 3 grupos C1-4 alcoxi o -S(O)pR8 (donde p es 0, 1 ó2), o R2 es un grupo seleccionado de C2-6 alquenilo, C2-6 alquinilo, C3-6 cicloalquilo y C3-6 cicloalquilC1-4 alquilo;o R1 y R2, junto con el nitrógeno al cual están unidos, forman un anillo de 5 a 7 miembros, anillo que puede sersaturado, insaturado o parcialmente saturado, en donde el anillo está sustituido con un grupo seleccionado de -OP(O)(OH)(OR) y C1-4 alquilo, estando dicho C1-4 alquilo sustituido con -OP(O)(OH)(OR), y en donde el anillo estásustituido opcionalmente además con 1, 2 ó 3 grupos C1-4 alquilo;R3 es un grupo seleccionado de hidrógeno, halo, ciano, nitro, C1-6 alcoxi, C1-6 alquilo;R4 es hidrógeno o un grupo seleccionado de C1-4 alquilo, heteroarilo, heteroarilC1-4 alquilo, arilo y arilC1-4 alquilo,grupo que está sustituido opcionalmente con 1, 2 ó 3 sustituyentes seleccionados de metilo, etilo, ciclopropilo yetinilo;R5 se selecciona de hidrógeno, C1-4 alquilo, C2-4 alquenilo, C2-4 alquinilo, C3-6 cicloalquilo y C3-6 cicloalquilC1-4 alquilo;R6 y R7 se seleccionan independientemente de hidrógeno, C1-4 alquilo, C3-6 cicloalquilo, y C1-4 alcoxi;R8 es hidrógeno o C1-4 alquilo;en donde R es un grupo protector lábil en medio ácido seleccionado de terc-butilo, tritilo, p-metoxifenilo, bencilo ofenilo.