baber/WOPTO huggingface dataset:
Patent CR-20200561-A (CR)
Title: Novel peptides and combination of peptides for use in immunotherapy against nhl and other cancers
Inventor: SCHOOR OLIVER
IPC: C07K14/47
Filed: 2017-02-17
Abstract: <p>The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.</p>
Patent CR-20210252-A (CR)
Title: Method and apparatus for plasma treatment of liquids in continuous flow
Inventor: SAONA ACUÑA MAXIMILIANO
IPC: C02F1/46
Filed: 2018-11-16
Abstract: The invention refers to a method, reaction chamber and system for the treatment of liquids in continuous flow, characterized in that said method comprises the following steps: a) receiving a liquid for treatment in a reaction chamber through at least one inlet opening in said reaction chamber, directing said liquid for treatment to an inlet section of the reaction chamber; b) converting the flow of liquid for treatment in a biphasic liquid-gas flow in said inlet section; c) directing the biphasic flow to a central section of the reaction chamber, where an electric field is applied; d) ionizing the gaseous fraction of the biphasic flow that passes through said central section, as a result of the interaction between the biphasic flow and the applied electric field; e) sustaining an ionization regime generating non-thermal plasma throughout the central section of the reaction chamber, where said regime is kept by controlling the electric field applied in said central section; f) leading the biphasic flow under the ionization regime to a discharge section of the reaction chamber, apart from the central section, where the electric field is applied, generating the deionization of the gaseous fraction and causing the biphasic flow to reduce its velocity, which results in the condensation of biphasic flow; and g) removing a flow of treated liquid from said discharge section through at least one discharge opening in the reaction chamber.
Patent CR-20220566-A (CR)
Title: Compounds and methods for modulating splicing
Inventor: AGRAWAL ANANT A
IPC: C07D487/04
Filed: 2021-04-08
Abstract: , modulate nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as methods of use thereof.
Patent EC-SP961918-A (EC)
Title: Estructura de celdas para confinamiento
Inventor: BACH GARY M
IPC: E01C3/06
Filed: 1996-11-01
Abstract: Una estructura de celdas para confinamiento para confinar material, que tiene una pluralidad de cintas plásticas alargadas dispuestas una al lado de otras y unidas a ciertos intervalos, formando áreas cerradas, en donde la pluralidad de cintas es capaz de extenderse a lo ancho para formar una red de celdas unitaria. Las cintas forman paredes de celdas, en donde al menos unas de las paredes de celda tiene una pluralidad de aperturas,m cada una de un diámetro que varia entre aproximadamente 3mm y 17m. Preferentemente cada una de las paredes de celdas tiene una pluralidad de aperturas, en donde el área total de las aperturas en las paredes de celda es de entre 19% y 28% del área total de la pared de celda.
Patent FI-20050097-A (FI)
Title: Network element for frequency synchronization of base station in cellular radio network, generates speed correction factor based on deviation of local clock time from reference time
Inventor: WESBY PHILIP
IPC: H04B7/26
Filed: 2005-01-28
Abstract: Network element (300) with reference clock (302) is fixed to base station (102) with local clock (330) via asynchronous data transmission connection (312). Reference clock sends time stamp signal (308) over connection. Station (102) receives time stamp signal and calculates deviation of local clock time from reference time. Based on deviation, speed correction factor is output and applied to local clock. A frequency synthesizer (212) generates frequency based on the corrected local clock. An independent claim is also included for the method of performing frequency synchronization of base station.
Patent GB-1050469-A (GB)
Abstract: 1,050,469. Lactams. INVENTA A.G. FUR FORSCHUNG UND PATENTVERWERTUNG. Oct. 30, 1963 [Nov. 2, 1962], No. 42893/63. Heading C2C. Lactams are made by treating cycloaliphatic hydroxymethyl compounds with a nitrosylating agent, whereby nitrosylation and oxidation take place, and the oximes formed are then rearranged in the reaction mixture by treatment with oleum to form the corresponding lactams. Suitable as nitrosylating agents are dinitrogen trioxide in the presence of concentrated sulphuric acid, or nitrosyl sulphuric acid. Examples describe the conversion of hydroxymethylcyclododecane to dodecane lactam, hydroxymethylcyclohexane to #-caprolactam, and hydroxymethylcyclooctane to capryl lactam.
Patent GB-1051248-A (GB)
IPC: B41L13/04
Abstract: 1,051,248. Printing-machines. AGFA A.G. Nov. 8, 1963 [Nov. 10, 1962], No. 44188/63. Heading B6C. A printing machine provided with means for effecting adjustment of the circumferential registration comprises a coupling member 6 secured to the shaft 2 of a stencil cylinder 3, a second coupling member 7 in the form of a gear wheel in permanent engagement with the driving mechanism of the machine, and a screw device 9a, 9b adapted to couple the members 6 and 7 over an angular range on rotation of a nut 12, said nut 12 supporting a gear-wheel 13 arranged to be rotated by a manually operable key 16 having a toothed portion 16a and being displaceable on an axis parallel to the longitudinal axis of the screw device. The head 9a of the screw device is secured against rotation with respect to the gear-wheel 7 by a pin 10 and complete unscrewing of the nut 12 is prevented by a retaining disc 14. The key 16 is loaded by a spring 18 and can be pushed through an opening 15a in the machine cover 15 to engage its toothed portion 16a with the gear-wheel 13. A further toothed portion 16b on the key forms a detachable coupling by way of a pin 19 with the shaft 2. The key is used to release the coupling screw device and the cylinder 3 is then rotated as required with respect to the gearwheel 7 or the cylinder is held stationary and the gear-wheel 7 is rotated by a hand wheel 20. The nut 12 is then tightened again by the key 16. A friction spring 22 between the coupling members 6 and 7 prevents undesired relative displacement.
Patent GB-1051899-A (GB)
IPC: B42D5/00
Abstract: 1,051,899. Books. KINCRAFT Ltd. July 5, 1965 [July 18, 1964], No. 29230/64. Headings B6A and B6E. In a holder for note pads &c. 17, of the kind having a front cover 8 hinged at 7 to a U -section member 1 which may be integral with a backplate 2, a separate resilient split sleeve 9 is located in the member 1 for holding a pencil. The plate 2 and member 1 may be of sheet metal and engage a note pad 17 resiliently. The sleeve 9 is of sheet metal and comprises a flat base 10 seated on the plate 2, and two flat side walls 11 which, when the sleeve is inserted in position, curve at the ends 13 to follow the contour 5 of the member 1. The ends 13 of the sleeve 9 do not meet, and define a gap 12, and the base wall 10 has a raised portion 14 on the inner face to define a flexible tongue which accommodates different sizes of pencils 15, Fig. 4 (not shown).
Patent GB-1053409-A (GB)
IPC: E02F3/38
Abstract: 1,053,409. Slewing mechanism for jib-cranes. STEELFAB Ltd. Nov. 5, 1965 [Nov. 26, 1964], No. 48183/64. Heading B8B. [Also in Division E1 A crane or excavator boom 14 pivoted at 11 on a structure 13 is slewed by hydraulic rams 16, 17 through at least 180 degrees. Cylinders 18, 22 of the rams are pivoted at 19, 23 to the structure 13 and their piston rods 20, 24 are pivoted to a jib-supporting bracket 10 at 21, 25. To slew the boom clockwise from the position shown in Fig. 1, fluid is supplied to chambers 18a, 22b. The ram 16 tends to turn the boom clockwise with an effective lever-arm R1, whilst the ram 17 tends to turn the boom anticlockwise with an effective lever arm R2. Since R1 is greater than R2 the boom rotates clockwise, the limiting position being illustrated in Fig. 3 (not shown).
Patent GB-1053506-A (GB)
IPC: F16K11/078
Abstract: 1,053,506. Valves. SPEAKMAN CO. INCORPORATED. March 18, 1965 [March 23, 1964], No. 11583/65. Heading F2V. In a hot and cold water mixing tap, inlets 28, 29 to a mixing chamber within a shell 13, retained within valve body 10 by a snap ring 50 and provided in the base thereof with an outlet 21 to a tap, are obturated by an imperforate portion of a vertically displaceable cylindrical closure element 32, attached to an operating spindle 36 by a spider 33 and manually displaceable by a directly attached handle, which is provided in the lower part thereof with apertures 48, 49 (Figs. 5-7 and 12, not shown) whereby, with the element 32 raised, the apertures 48, 49 may be progressively aligned with inlets 28, 29 upon rotation of element 32 so that flow may occur entirely through one or other of the inlets or in progressively varying amounts through both inlets simultaneously, the total flow remaining substantially constant. Sealing 0-rings 18, 20 are retained by shell 13 to act around the inlets 28, 29 between the valve body 10 and closure element 32 and the shell 13 is sealed to the body 10 by circumferential 0-rings 14, 15 at either end thereof and sealing between inlets 28, 29 is effected by a diagonally situated 0-ring 16. Operating spindle 36 is provided with a vent 35 and is sealingly guided upon stud 30 fixed in the valve body 10 or, alternatively, the spindle may be sealingly guided within a blind bore in an upstanding portion of valve body 10 or may pass through an opening in the valve body base; each arrangement is pressure balanced to avoid "creeping" of the valve when in the partially open position. The diagonal 0-ring 16 may be replaced by O-rings 85, 86 (Figs. 17 and 20, not shown) retained within an annular polytetrafluoroethylene ring shaped to the surface of closure element 32 and provided with an 0-ring retaining skirt. In a further embodiment (Figs. 21-23, not shown) the valve may be used in a combination shower-bath installation with the valve outlet opening directly into the bath discharge port which is connected by an annular valve body passage to the diametrically opposed and upper shower outlet port whereby the force of the direct discharge into the bath port merely creates suction in the shower port to which flow is diverted when required by a further valve in the bath discharge faucet.
Patent GB-1053546-A (GB)
IPC: B60Q3/02
Abstract: 1,053,546. Vehicle rear view mirrors. WINGARD Ltd. June 28, 1963 [May 31, 1962], No. 30697/66. Heading B7J. A combined rear view interior mirror and lamp comprises a metal or plastics hollow arm 58 supporting a boss 57 mounting an adjustable mirror 56 and a lamp 61. A lamp lens 63 slidably engages with ribs on the boss (see also Fig. 3 (not shown).
Patent GB-1053814-A (GB)
IPC: H01H51/28
Abstract: 1,053,814. Electromagnetic relays. STANDARD TELEPHONES & CABLES Ltd. Sept. 18, 1964 [Sept. 20, 1963], No. 38187/64. Heading H2B. A contact assembly comprises at least one sealed magnetic reed contact unit 2 and a biasing magnet 3 embedded in a block 1 of insulating material. The block has a rigid projection 8 at one end and a projection 6 carried by a resilient tongue 7 at the other end and is inserted into a coil former by deflecting the projection 6 out of the path of the coil former, the projections 6 and 7 co-operating with the former to retain the contact assembly in its inserted position. The magnet may bias the contacts closed or merely hold them in position after actuation.
Patent GB-1054450-A (GB)
IPC: H01L29/00
Abstract: 1,054,450. Coating with glass; glass-metal materials. PHILCO CORPORATION. Sept. 25, 1964 [Sept. 26, 1963], No. 39156/64. Heading C1M. [Also in Division H1] The semi-conductor wafer of a silica coated planar silicon transistor (Fig. 2), is provided with further passivating coating by heating to 600 C. in an evacuated vessel containing vaporized high silica-borosilicate glass and tungsten. The vapour is generated by heating a tungsten filament wound round a borosilicate glass rod to 2000-2400 C., the actual temperature determining the tungsten content of the coating. This should be 16-20% by weight to ensure that the expansion coefficient of the glass matches that of silicon. Apertures are subsequently etched in the glass to accommodate contacts 26 to the transistor electrodes.
Patent GB-1054619-A (GB)
IPC: D03J5/00
Abstract: 1,054,619. Bobbin damps. E. KENK. Nov. 15, 1965 [Dec. 11, 1964; Jan. 9, 1965], No. 48321/65. Heading DIE. A bobbin clamp has resilient limbs which are divided into individual members. The bobbin clamp may be a single 'U' shaped member in which the individual members are produced by slitting the limbs longitudinally. or it may be formed of several 'U' shaped laminae which are secured together by bolts or rivets. The laminae may be pressed out or formed of spring steel wire. Extensions may be formed on the legs of the laminae Figs. 9 and 11 (not shown) which bear against the insides of the shuttle to give increased resilience. Nylon or other synthetic plastics material may be used in the formation of the laminae. Wear resistent plates may be provided on the inside of the shuttles for example where the said extensions bear upon them.
Patent GB-1226352-A (GB)
IPC: A47B95/04
Filed: 1968-03-26
Abstract: 1,226,352. Clips. W. G. COX & SON Ltd. 14 March, 1969 [26 March, 1968], No. 14506/ 68. Heading E2B.  A mirror 6, Fig. 2, is secured to a door panel 4 by a channel-shaped plastics clip 8 running along the edges of both and having a slightly inturned limb 10 gripping the mirror. The channel is secured by a notched flange 16 pressed into a groove 18 in the edge of the door and by a third limb 14 at the inside of the door. (For Figure see next page)
Patent GB-1227802-A (GB)
IPC: C01B33/10
Filed: 1968-07-05
Abstract: 1,227,802. Recovery of P 2 0 5  and/or F values. ARMOUR AGRICULTURAL CHEMICAL CO. 5 July, 1968 [7 July, 1967; 29 Nov., 1967], No. 32135/68. Heading C1A. P 2 0 5  and/or F values are recovered from dilute aqueous solution by mixing the solution with concentrated H 2 S0 4 , collecting fluorine and silicon containing vapours which are driven off by the heat of dilution of H 2 S0 4  and recovering the P 2 O 5  in dilute H 2 SO 4 . The fluorine and silicon containing vapours may be contacted with water to produce fluosilicic acid. The dilute H 2 S0 4  produced may be used to digest phosphate rock. The dilute aqueous solution is preferably drawn from a pond which is open to the atmosphere and which is supplied with wash waters from a plant manufacturing phosphate materials. Phosphate rock may be digested, filtered and washed to produce slurry and filtrate streams, at least one of which streams being recycled to the digestion step; the recycle stream which is in aqueous solution is treated with concentrated-H 2 SO 4  as above. The dilute aqueous solution from the pond may be first used as wash water for digested phosphate rock before being used to dilute the H 2 SO 4 . The phosphoric acid which is withdrawn from the digestion of phosphate rock may be concentrated under pressure which is maintained by a barometric condenser and concentrated H 2 SO 4  may be introduced into the barometric condenser in contact with vapours from the concentration zone to dilute the H 2 S0 4  which is then contacted with the recycle stream.
Patent GB-1229764-A (GB)
IPC: F04B7/02
Filed: 1970-01-27
Abstract: 1,229,764. Valves. F. W. SCHWING. 27 Jan., 1970 [5 Feb., 1969], No. 3835/70. Heading F2V. A control valve, which is suitable for use in conjunction with a concrete-conveying pump, comprises a closure member 2 having oppositely directed projections 19 within which are fixedly received valve operating shafts 4, a housing within which the valve member moves and which is formed from two abutting and identical bearing plates 20 terminated at each end by twopart stop plates 23, the bearing and stop plates together defining two ports 3 each of which registers with one duct leading from the pump, and a pair of piston and cylinder valve actuators 6. Each operating shaft 4 has secured to its end a piston 12 with such piston co-operating with a cylinder 13 secured by a nut 16 to the valve housing, the nut 16 also serving to adjust a packing 5 surrounding each shaft 4. Covering each shaft 4 and extending between its piston 12 and the valve member projection 19 is an erosion tube 10 the outer diameter of which is smaller than the inner diameter of the cylinder 13 such that an intermediate space 7 is formed therebetween, the space communicating via a line 8 with a tank 9 containing flushing liquid. In operation, a multi-way valve 25 determines the direction of movement of the operating shafts 4 and hence of the valve member 2. In consequence, if piston 12 moves in the direction of arrow a, flushing liquid is drawn into the space 7 and so cleans the portion of the shaft within such space. On the return stroke, with motion in the direction of arrow b, the flushing fluid and impurities entrained therein are returned to the tank 9 where such impurities settle, the tank 9 being made at least in part of transparent material to so facilitate viewing of the accumulation of impurities. In modifications (Figs. 5 and 6, not shown), the valve member may be carried by one shaft only, or alternatively, two valve members may be arranged in series in the longitudinal direction of one valve actuating rod.
Patent GB-1232159-A (GB)
IPC: H01J23/00
Filed: 1969-08-14
Abstract: 1,232,159. Magnetrons. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. 14 Aug., 1969 [17 Aug., 1968], No. 40736/69. Heading H1D. The cathode 3 of a magnetron is supported by coaxial conductors 2, 6 which pass through one of the pole shoes 10 of the tube and are terminated by a connection device comprising a plug 100 having an inner annular flange 102 which may be clamped to the inner conductor 6 and an outer annular flange 101 which forms an RF choke in conjunction with a tubular extension 105 of the outer conductor 2. The tube 105 is clamped to the end of the conductor 2 by a band 106. Power connections are made to lugs (not shown) held in position by screw 104 and by the clamping screw of clamping band 106. The anode structure comprises radial vanes 13 strapped alternately by rings 16, 17. The inner conductor 23 of output line 19, 23 is connected to a strap 15 which connects the vanes of two adjacent cavities. The output line terminates in an annular window 25 which may be inserted into a waveguide or resonant cavity.
Patent GB-1234682-A (GB)
IPC: F23Q7/10
Filed: 1969-02-21
Abstract: 1,234,682. Blowpipe burners. GRIESHEIM G.m.b.H. 21 Feb., 1969 [24 Feb., 1968], No. 9470/69. Heading F4T. To ignite an autogenous cutting torch, particularly in multi-torch cutting machines, the heating mixture of fuel gas and oxygen is introduced into the cutting oxygen duct and ignited therein or in a subsidiary duct connected thereto. In a first embodiment of cutting torch, Fig. 1, having inlets 11, 12, 13, for cutting oxygen, heating oxygen and fuel gas respectively, and a nozzle 22 with a cutting oxygen outlet 23 and a concentric circle of bores 24 for the heating mixture of oxygen and fuel produced within the torch, during ignition the cutting oxygen is turned off and part of the heating oxygen is diverted via a pipe 26 to an injector 28 where it creates suction in an annular passage connected to the cutting oxygen duct via a pipe 30. As the heating gas mixture leaves the bores 24, part is drawn into duct 21 and pipe 30, is ignited by an electrical incandescent igniter 33 screwed into pipe 30, and burns back to ignite the mixture issuing from the bores 24. An electromagnetic valve 31, open only when current flows through the igniter, controls passage of gas through pipes 26 and 30, and preferably a device is provided to carry out the ignition and switching current off operations automatically within about two seconds. A flame barrier 34 is disposed in pipe 30 between the valve 31 and the igniter, and the oxygen inlet has a non-return valve 14. In a second embodiment, Figs. 2, 3 (not shown), the igniter is disposed in the cutting oxygen duct downstream of a one-way valve interconnecting the cutting oxygen and heating gas mixture ducts, so that when the cutting oxygen is off, heating gas mixture flows past the igniter and the ignited gas continues to burn as far as the nozzle cutting oxygen outlet where it ignites heating mixture issuing from the heating mixture outlet bores. In operation, the cutting oxygen pressure prevents operation of the one-way valve. A flame barrier of porous, non-combustible material is disposed in the valve casing. In either embodiment, the fuel gas and heating oxygen inlets are provided with valves having control knobs calibrated from zero to eight so that the optimum mixture is obtained for any standard size of nozzle when both valves are set to the same predetermined work.
Patent GB-1238374-A (GB)
IPC: F16B31/02
Filed: 1968-07-30
Abstract: 1,238,374. Torque limited joints. HI-SHEAR CORP. 30 July, 1966 [31 July, 1967], No. 23845/68. Heading F2H. A joint adapted to be assembled to a predetermined torque level comprises a workpiece with a cylindrical hole, a pin 10 with a thread 13 and a collar 26 with an internal thread 37. The pin has a first diameter 15 on a portion 12 which is an interference fit in the hole in the workpiece and the threaded portion has a second diameter 16 which is no greater than diameter 15. Wrench engaging means 18 are provided in the form of a socket in the pin end 14. The collar comprises a bearing section 27 and a wrench engaging section 28. The bearing section has a bearing face 30 which contacts a face of the workpiece, and a bore comprising a counterbore 38 and the threaded bore 37. The wrench engaging section is joined to section 27 by a weakened portion formed by groove 29 such that on tightening the collar, the collar fractures at groove 29 when a predetermined tension is reached. The length of the counterbore 38 is such that when assembled, the incomplete threads 13a of the pin are not engaged by the collar threads such that the collar thread engages at least three complete convolutions of threads of the pin.
Patent GB-1238439-A (GB)
IPC: F16D13/64
Filed: 1970-05-21
Abstract: 1,238,439. Friction clutches. GENERAL MOTORS CORP. 21 May, 1970 [31 May, 1969], No. 24590/70. Heading F2C. A friction clutch plate comprises metal segments 35, 36 riveted to a support disc (32), Fig. 3 (not shown), each segment 35 having a central flat portion to which a friction lining 38 is adhered, and bentover edge portions 35a, 35b providing resiliency and hence cushioning clutch engagement. The segments 36 have adhered thereto a continuous friction lining 39 or, Fig. 5 (not shown), separate friction linings (40). The segments are preferably non-aligned as shown. As described, the clutch plate forms the driven disc (16), Fig. 1 (not shown), of a diaphragm spring engaged vehicle clutch in which the presser plate (18) is connected to the driving cover by resilient straps (19).