baber/WOPTO huggingface dataset:
Patent EA-017291-B1 (EA)
Title: Rage fusion proteins, formulations, and methods of use thereof
Inventor: MJALLI ADNAN M M
IPC: A61K38/17
Filed: 2007-04-25
Abstract: Disclosed are RAGE fusion proteins comprising RAGE polypeptide sequences linked to a second, non-RAGE polypeptide. The RAGE fusion protein may utilize a RAGE polypeptide domain comprising a RAGE ligand binding site and an interdomain linker directly linked to the N-terminus of an immunoglobulin C2 domain. Also disclosed are RAGE fusion protein formulations and the use of the RAGE fusion proteins and RAGE fusion protein formulations as therapeutics for RAGE-mediated pathologies.
Patent EA-012690-B1 (EA)
Title: Actuator device
Inventor: HODNEFJELL LARS GUNNAR
IPC: F16K31/04
Filed: 2007-07-02
Abstract: An actuator device (1) comprising an actuator housing (2) with a fitting (4) for connecting the actuator (1) to an object (6), a motor (28) which via transmission elements (30, 32, 38, 40) drives an output actuator shaft (12) of the actuator (1), where the actuator shaft (12) is rotationally disconnectable from the motor (28), the actuator shaft (12) being rotatable between two angular positions where the one angular position may correspond to the object (6) being in a first condition and the other angular position may correspond to the object (6) being in a second condition, and where the actuator (1) is provided with an element (14) for storage of mechanical energy, the element (14) by energy cut-off to the actuator (1) being releasably arranged to be able to displace a nut (44) being prevented from rotating around its longitudinal axis, along a screw thread (42); complementary fitting to the nut (44), and connected to the actuator shaft (12), whereby the actuator shaft (12) is rotated between the two angular positions.
Patent EA-017960-B1 (EA)
Title: 1,8-diazospiro[4,5]decane-8-carboxamide derivatives having antagonist activity against nk1 receptor
Inventor: ALVARO GIUSEPPE
IPC: A61P25/22
Filed: 2009-04-29
Abstract: Compounds of formula (I) or a pharmaceutically acceptable salt thereofwherein R is hydrogen or Calkyl; R1 is hydrogen, Calkyl, C(O)OH, C(O)NHor (Calkylene) R10; R2 and R3 are independently hydrogen, Calkyl or R2 together with R3 and together with the carbon atom to which they are attached form a Ccycloalkyl group; R4 is Calkyl, Calkoxy or halogen; R5 and R7 are independently hydrogen, hydroxy, halogen, C(O)NH, C(O)OH or (Calkylene) R10; R6 and R8 are independently hydrogen or halogen; R9 is hydrogen, (Calkylene) R10, C(O)NH, C(O)OH or R9 together with R form a 6 membered heterocyclic ring optionally containing a further heteroatom selected from oxygen, sulphur or nitrogen; R10 is hydrogen, halogen, hydroxy, C(O)NH, C(O)NH(Calkyl), C(O)N(Calkyl)or C(O)OH; n is 0, 1 or 2; processes for their preparation, to compositions containing them and to their use in the treatment of diseases and conditions for which antagonism of NK1 is beneficial.
Patent EA-020108-B1 (EA)
Title: Process for producing a methylsilicic acid hydrogel
Inventor: KABACHNYI GENNADII IVANOVYCH
IPC: C01B33/155
Filed: 2010-06-14
Abstract: The invention relates to the production of adsorbents and specifically to a process for producing a methylsilicic acid hydrogel. A working mixture comprising methyltriethoxysilane (MTES) and an aqueous solution of ethanol with ethyl alcohol in a proportion by volume of from 60 to 96.5%, a hydrolyzed mixture of hydrochloric acid and purified water, and an alkaline solution. The MTES is hydrolyzed in the presence of an acidic catalyst with subsequent alkaline treatment, the reaction mass is left to stand, and the resultant methylsilicic acid alcogel is comminuted and is then washed with purified water to give a hydrogel. The volume ratio of the MTES to the aqueous ethanol solution is 1:2.1, 1:2.4, 1:3, 1:3.3. The MTES is used in a proportion by mass of the basic substance of at least 98%. The MTES is hydrolyzed in a volume ratio of working mixture to hydrolyzing mixture of 3-3.5:0.7-1.5. The time for introducing the hydrolyzing mixture into the reaction mass is 30-40 min. The resultant reaction mixture is left to stand for 3-3.5 hours at pH of at least 3. After completion of the MTES hydrolysis, an alkaline solution is introduced into the resultant reaction mass at a temperature of 16-30°C, and then the resultant methylsilicic acid alcohydrogel is left to stand to mature for at least 7.5 hours; the maturing process is performed until a colorless intermediate with slight opalescence is produced. The comminuted methylsilicic acid alcohydrogel is washed with purified water at a rate of 2-4 l per hour. The invention makes it possible to increase the adsorption activity of the methylsilicic acid hydrogel by 2.0-3.9 times and to reduce the ethyl alcohol consumption by 30-40%.
Patent EA-024077-B1 (EA)
Title: Method for screening inhibitors/blockers of hiv-1, pseudo-hiv-1 particle replication and set for method realisation
Inventor: PRASOLOV VLADIMIR SERGEEVICH
IPC: C12Q1/00
Filed: 2012-06-27
Abstract: The invention relates to medicine, namely to molecular biology, and can be used for screening potential inhibitors/blockers of HIV-1 replication. The essence of the invention consists in method for screening inhibitors/blockers of HIV-1 replication, which includes addition of the tested inhibitor/blocker of HIV-1 replication to sensitive cells, and further addition of pseudo-HIV-1 particles to sensitive cells, detection of fluorescence of sensitive cells and determination of efficiency of impact of inhibitor/blocker of HIV-1 replication on pseudo-HIV-1 particles basing on the number of fluorescenting cells in transduced population. Said pseudo-HIV-1 particles include protein of envelope of vesicular stomatitis G virus, enzyme of HIV-1 reverse transcriptase, enzyme of HIV-1 intergrase, HIV-1 structural proteins, forming protein framework of viral particle and gene of green fluorescent protein (GFP), where enzyme of HIV-1 reverse transcriptase and enzyme of HIV-1 intergrase are mutant form. To realise the method for screening inhibitors/blockers of HIV-1 replication, disclosed is a set, which includes panel of pseudo-HIV-1 particles, including pseudo-HIV-1 particles in which integrase enzyme and enzyme of reverse transcriptase of HIV-1 are a form of wild type without drug resistance, cells of lines HEK-293, SC-1, Jurkat, CEM-SS and Kasumi-1 and DMEM medium with addition of 10% cattle embryonic serum, 4 mM of L-glutamine, 100 U/ml of penicillin, 100 mcg/ml of streptomycin for lines of cells HEK-293 and SC-1, RPMI-1640 medium with addition of 20% FCS, 4 mM of L-glutamine, 100 U/ml of penicillin, 100 mcg/ml of streptomycin for lines of cells Jurkat, CEM-SS and Kasumi-1; standard phosphate buffer PBS.
Patent EA-025300-B1 (EA)
Title: Method of making particulate material
Inventor: CUYPERS JEAN MARIE WILHELMUS
IPC: C04B18/02
Filed: 2010-06-22
Abstract: The invention relates to a method of making a particulate material comprising using mineral wool as base material comprising at least 80% particles with a size not more than 40 mm, and preferably having water content not more than 70%, subjecting the mineral wool base material to sintering by use of a pulse combustor and thereby forming a particulate material in the form of particles having size at least 80% not more than 20 mm. An apparatus for carrying out the method comprises means for size reduction of coherent mineral wool substrate and a reaction chamber in communication with a pulse combustor.
Patent EA-026351-B1 (EA)
Title: Apparatus for minimizing bypass in ammonia oxidation burners of industrial plants with burner diameters of 2-7 m in natural- or forced-circulation boilers
Inventor: FUCHS JUERGEN
IPC: C01B21/28
Filed: 2012-09-07
Abstract: The invention relates to a system of a burner basket for ammonia oxidation burners for industrial plants with burner diameters of 2-7 m in a natural- or forced-circulation boiler suitable for minimizing gas slip and for minimizing wave formation of means contained in the burner basket, and also for minimizing loss of means contained in the burner basket, wherein the burner basket has a wall (1) that is anchored in the ammonia oxidation burner and the burner basket has a gas-permeable bottom plate (2), which is placed on internal fittings of the forced circulation boiler, wherein the wall (1) and the gas-permeable bottom plate (2) are not mechanically connected to each other, and the wall (3) of the burner basket tapers conically towards the bottom plate at an angle of 5-20° from the perpendicular, and in all operating states of the ammonia oxidation burner there is a peripheral gap in the range from 5 to 10 mm between the wall (1) and the gas-permeable bottom plate (2).
Patent EA-025933-B1 (EA)
Title: Zero point calibration method and apparatus for pressure sensor of anesthesia machine
Inventor: ZHANG YAODONG
IPC: A61M16/00
Filed: 2013-10-22
Abstract: Disclosed are a zero point calibration method and apparatus for a pressure sensor of an anesthesia machine. The method comprises performing zero point calibration of an airway pressure sensor of the anesthesia machine (110); restarting and carrying out starting up self-testing (120); and judging whether pressure change values of the airway pressure sensor and an ambient pressure sensor are the same, and if the values are the same, performing zero point calibration of the ambient pressure sensor according to a zero point of the airway pressure sensor (130). The method can realize zero point calibration of a pressure sensor of an anesthesia machine by means of the simple operation, avoiding error in operation.
Patent EA-033451-B1 (EA)
Title: Process of asymmetric hydrogenation of ketals and acetals
Inventor: BONRATH WERNER
IPC: C07D317/50
Filed: 2013-12-18
Abstract: The present invention relates to a process of the asymmetric hydrogenation of ketals of unsaturated ketones or acetals of unsaturated aldehydes by molecular hydrogen in the presence of at least one chiral iridium complex of formula (III), wherein groups and symbols in formula (III) have the meanings defined herein. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced.
Patent EA-031991-B1 (EA)
Inventor: PARK JEONG BEOM
IPC: C08J7/12
Filed: 2014-04-25
Abstract: Изобретение, в целом, относится к способу получения дополнительно обработанных поверхностно сшитых водоабсорбирующих полимерных частиц; к дополнительно обработанной поверхностно сшитой водоабсорбирующей полимерной частице, полученной указанным способом; к множеству дополнительно обработанных поверхностно сшитых водоабсорбирующих полимерных частиц; к композиционному материалу, содержащему указанные дополнительно обработанные поверхностно сшитые водоабсорбирующие полимерные частицы или указанное множество дополнительно обработанных поверхностно сшитых водоабсорбирующих полимерных частиц; к способу получения композиционного материала; к композиционному материалу, полученному указанным способом; к применению дополнительно обработанной поверхностно сшитой водоабсорбирующей полимерной частицы или множества дополнительно обработанных поверхностно сшитых водоабсорбирующих полимерных частиц; к устройству для получения дополнительно обработанных поверхностно сшитых водоабсорбирующих полимерных частиц и к способу получения дополнительно обработанных поверхностно сшитых водоабсорбирующих полимерных частиц с применением указанного устройства.
Patent EA-037839-B1 (EA)
Title: Particles for the release of active ingredients
Inventor: RAMETSTEINER KARL
IPC: A01P19/00
Filed: 2015-11-11
Abstract: The invention relates to particles (1) with a controllable release of at least one pheromone, wherein a) the particle (1) has a core (2) which is surrounded by one or more layers (4, 6), and b) the core (2) and at least one layer (4, 6) surrounding the core (2) comprise at least one pheromone to be released, wherein the core (2) and/or at least one layer (4, 6) surrounding the core (2) comprise a substrate for binding or for absorbing the at least one pheromone to be released, wherein the substrate comprises zeolite, and the substrate is capable of dispensing the absorbed pheromone in a delayed manner.
Patent EA-033885-B1 (EA)
Title: ANTIMICROBIAL COMBINATION FOR CARBAPENEM-RESISTANT GRAM-NEGATIVE BACTERIA OF THE SPECIES ACINETOBACTER BAUMANNII PRODUCING METAL-β-LACTAMASE
Inventor: AFINOGENOVA ANNA GENNADIEVNA
IPC: A61P31/04
Filed: 2017-11-23
Abstract: The invention relates to the field of medicine, and more particularly to clinical microbiology and can be used to overcome the resistance of gram-negative microorganisms of the species Acinetobacter baumannii producing metal-β-lactamase (MβL), to carbapenems. The above technical result is achieved by the fact that clodronic or etidronic acids from the group of biphosphonates inhibit the standard reagent, i.e. recombinant metal-β-lactamase of P. aeruginosa expressed in Escherichia coli. The achieved result allowed to reveal the antimicrobial effect of the combination of clodroic or etidronic acids with carbapenems (imipenem or meropenem) regarding the reference strain A. baumannii ATCC BAA-747 resistant to carbapenems in presence of standard reagent MβL inactivating these antibiotics. The proposed technical solution allows to model generation of Gram-negative microorganism strains with different resistance level to carbapenems and assess the efficiency of metal-β-lactamase inhibition.
Patent EA-034840-B1 (EA)
Title: Metallic fastener with a threaded portion, process for coating same and coating composition for threads
Inventor: DE BRUINE PIETER ISAAC
IPC: F16B33/06
Filed: 2016-05-12
Abstract: The present invention provides a metallic fastener comprising a threaded portion, wherein at least part of the threaded portion is coated with a composition. The composition is hard, FDA-approved and essentially consists of (a) a paraffin wax with a melting temperature in the range of 50 to 70°C, (b) 1 to 5 parts by weight (pbw) of a resin per pbw of paraffin wax, (c) 0.1 to 0.25 pbw graphite per pbw of paraffin wax, and (d) 0.05 to 0.30 pbw of an FDA-approved silica per pbw of paraffin wax. Moreover, the present invention provides a process for coating a metallic fastener comprising a threaded portion, comprising the following steps: (i) providing a composition as defined above, (ii) maintaining the fastener or bringing it to a temperature in the range of 30 to 70°C, (iii) applying the composition at a temperature in the range of 100 to 170°C, (iv) optionally, removing surplus composition, (v) cooling the fastener to less than 100°C, (vi) finishing the fastener in a water bath, and (vii) drying the fastener. Also provided is a process for powder coating the metallic fastener.
Patent EA-035076-B1 (EA)
Title: Wall made up of an assembly of pallets, assembly modules, method for creating a building or a wall
Inventor: ESCRIVA JEAN-CLAUDE
IPC: E04B2/02
Filed: 2016-07-22
Abstract: The invention relates to a wall (100) comprising a framework of pallets (10) assembled in horizontally juxtaposed and vertically superposed vertical positions. In the wall, two juxtaposed pallets (10) of a row are immobilized with respect to one another by at least one horizontal assembly module (MH) collaborating along a long side (17) of each of the said juxtaposed pallets via protrusions (24) secured to a sole (21) of the horizontal module, collaborating with openings (171) formed on the long sides (17) of each of the said pallets between two successive blocks, an edge (14) and a sole (11). In the wall, vertically superposed pallets (10) are immobilized with respect to one another by at least one vertical assembly module (MV) collaborating along a short side (18) of each of the superposed pallets by crenels (32) secured to a base (31) of said vertical module, collaborating with canals (181) opening onto the short sides (18) of each of the said pallets between two successive blocks secured to a crossmember (13). Spacer modules are used to hold two walls apart to form the framework of a rampart.
Patent EA-038121-B1 (EA)
Title: Permanent magnet based electric machine having enhanced torque
Inventor: REDDY PATEL BHAGEERATH
IPC: H02K1/22
Filed: 2018-04-20
Abstract: An electric machine is presented. The electric machine includes a stator and a rotor disposed adjacent to the stator. The rotor includes a rotor core and permanent magnets disposed in contact with the rotor core to modulate torque exerted on the rotor.
Patent EA-039271-B1 (EA)
Title: Device and method for removal of pollutants from gas streams
Inventor: Weagle Glenn Eric
Filed: 2017-04-20
Abstract: A filtering device is provided for filtering pollutants from a gas stream. The device includes a cartridge comprising an inner perforated passage, an outer perforated jacket, one or more non-perforated ends and a sorbent bed contained between the inner passage and the outer jacket; and a outer shell containing the cartridge and having a first port in fluid communication with the inner perforated passage and a second port in fluid communication with the outer perforated jacket. A flowpath of the gas stream into any one of the first port or the second port, through the sorbent bed and out of the other of the first port or the second port is a bidirectional flowpath. A method is further provided for filtering pollutants from a gas stream. The method includes the steps of allowing the gas stream to flow into a filtering device in a first direction, the device comprising a cartridge having a sorbent bed contained therein; directing the gas stream to bend in a second direction differing from the first direction as it enters the sorbent bed; and allowing the gas stream to pass through the sorbent bed and to exit the device.
Patent EA-037725-B1 (EA)
Title: Drive of a downhole pump
Inventor: Leonov Vyacheslav Vladimirovich
IPC: F04B47/06
Filed: 2018-09-12
Abstract: The invention relates to oil production equipment and can be used for actuating submersible downhole plunger pumps in the operation of marginal wells. A drive of a downhole pump comprises a housing, a submersible electric motor with a protector, the drive shaft of which is coupled to the screw of a ball screw actuator that is movably coupled to the housing and is coupled to a rod which is sealed inside the housing. The interior cavities of the housing are filled with oil and are in communication with the borehole cavity via an elastic membrane. The drive shaft of the electric motor is connected to the ball screw actuator via a reverse reduction gear having a switching mechanism. The reverse reduction gear is switched only when the nut of the ball screw actuator (or of an additional ball screw actuator) arrives at its terminal positions, thus improving the operational reliability of the drive. The electric motor operates in a continuous mode, which increases the reliability and energy efficiency of the drive owing to the absence of repeated starting and stopping of the electric motor; consequently, a spike in current intensity upon start-up is avoided. Therefore, the solutions used in the invention make it possible to improve the reliability and energy efficiency of the drive of a downhole pump.
Patent ES-2162605-B1 (ES)
Title: Sistema modular de conmutacion en tiempo real para equipos electronicos de comunicaciones.
Inventor: ORTIZ GARCIA FERNANDO
IPC: H04Q1/14
Filed: 2000-05-24
Granted: 2003-04-01
Abstract: Sistema modular de conmutación en tiempo real para equipos electrónicos de comunicaciones, tanto de producción como de reserva, destinado para aquellos centros que por su criticidad requieren un servicio de operación ininterrumpido. Permite cambios de topología en casos de emergencia o simplemente para poder hacer pruebas para incorporar nuevos servicios o productos en un tiempo muy reducido. Consta de interfaces de línea de entrada/salida (LE)/(LS), bus de control(BC),fuente de alimentación conmutada (FAC) y sistema microprocesador de control y monitorización integrados (M) así como programas de control externo.
Patent ES-2189624-B1 (ES)
Title: Procedimiento para la concentracion de zumos.
Inventor: MENDOZA TURRO AGUSTIN
IPC: A23L2/12
Filed: 2001-02-19
Granted: 2004-10-16
Abstract: Procedimiento para la concentración de zumos. Comprende una primera fase en la que el zumo recién exprimido (1) es sometido a clarificación y ultrafiltración (3) obteniéndose un zumo clarificado (7), y pulpa o sólidos (5) que se guardan para una fase posterior, una segunda fase donde el zumo clarificado (7) es sometido a ósmosis inversa (9), hasta conseguir una concentración (13) de sólidos solubles y unas pulpas (11) que también se guardarán para una fase posterior, una tercera fase de concentración, donde el zumo (13) pasa por un generador de hielo líquido (15, 15a, 15b, 15n), tras lo cual dichos microcristales (51) se separan del líquido mediante centrifugación (19) o vacío, una cuarta fase (27) en la que se combinan los sólidos o pulpas con el concentrado (21) saliente de la centrifugación (19) o vacío.
Patent ES-2190897-B1 (ES)
Title: Matrices de conductos capilares de utilidad quimica y biologica.
Inventor: GANAN CALVO ALFONSO M
IPC: C40B40/12
Filed: 2002-02-04
Granted: 2005-02-01
Abstract: Matrices de conductos capilares de utilidad química y biológica. El objeto de esta invención es un procedimiento para la fabricación de matrices de conductos capilares para la realización in situ de procesos de interacción química o biológica, formada por láminas adheridas entre sí a lo largo de su superficie. Dichas matrices son de especial utilidad, pero no exclusivamente, mediante su sección en láminas, para producir micromatrices bidimensionales de sustancias químicas o biológicas. Los campos de aplicación de esta invención están relacionados con los campos en los que se emplean las metodologías de la Química Combinatoria, el Análisis Molecular por reconocimiento específico, y en particular para su uso en Biología, Biología Molecular, Bioquímica, Biotecnología, Genética, Medicina, Farmacia, etc. Además, este método puede aplicarse como técnica de impresión de muy alta resolución para la producción de sustratos en los que aparece una imagen indeleble aunque se desgaste y erosione la superficie indefinidamente.
Patent ES-2233212-B1 (ES)
Title: Cabezal de maquina herramienta.
Inventor: NICOLAS-CORREA JOSE-IGNACIO
IPC: B23Q16/10
Filed: 2001-04-19
Granted: 2006-11-01
Abstract: Cabezal de máquina herramienta que incluye un
dispositivo de posicionamiento con  división diferencial, de los
constituidos  por un cuerpo fijo (1) que dispone de  una corona con
dentado frontal con un número de dientes N1, un segundo cuerpo  (3)
portador de una segunda corona frontal con un número de dientes N2 y
un  tercer cuerpo intermedio (2) formado por dos dentados frontales
enfrentados que  posee en una de sus caras un número de dientes N1 y
en la opuesta un número de  dientes N2 coincidentes y en relación
con los dientes de las coronas de las  piezas (1) y (2),
caracterizado porque el valor del ángulo mínimo alcanzado en  el
posicionamiento, que viene dado por la diferencia entre el ángulo
entre  dientes de la primera corona y el ángulo entre dientes de la
segunda corona, es  un número decimal exacto. 
     Este ángulo mínimo de desplazamiento diferencial
es de 0,1º para lo cual los  números de datos son 144 y 150 dientes
respectivamente. Cuando el ángulo mínimo  diferencial es de 0,05º el
número de dientes es de 119 y 121, mientras que  cuando el ángulo de
desplazamiento diferencial es de 0,5º el número de dientes  es de
144 y 120.
Patent ES-2261028-B1 (ES)
Title: Filtro y superficies selectivas en frecuencia.
Inventor: SOROLLA AYZA MARIO
IPC: H01P1/20
Filed: 2004-08-20
Granted: 2007-11-16
Abstract: Filtro y superficies selectivas en frecuencia que comprenden un medio (11) de propagación guiado para energía electromagnética adaptado para alojar anillos (12) resonantes abiertos y/o anillos (12) resonantes abiertos complementarios dispuesto en un plano (13) transversal a la dirección de propagación del medio de propagación guiado.