baber/WOPTO huggingface dataset:
Patent CA-2428441-A1 (CA)
Inventor: HARTMANN DAN-PAUL
IPC: C12Q1/68
Filed: 2001-11-20
Abstract: L'invention concerne des dispositifs, des réseaux, des kits et des procédés permettant de détecter des biomolécules dans une section tissulaire (telle qu'un échantillon frais ou d'archives, un micro-réseau tissulaire ou des cellules rassemblées au moyen d'une procédure LCM) ou dans d'autres échantillons sensiblement bidimensionnels (tels qu'un gel électrophorétique ou un micro-réseau d'ADNc) par création de "copies à carbone" des biomolécules eluées à partir de l'échantillon et par visualisation des biomolécules sur les copies, au moyen d'au moins une molécule de détention (par exemple, des anticorps ou des sondes d'ADN) présentant une affinité spécifique pour les biomolécules à étudier. L'invention concerne également des procédés spécifiques permettant d'identifier le schéma des biomolécules (par exemple, des protéines et des acides nucléiques) dans les échantillons. L'invention concerne, en outre, d'autres procédés spécifiques permettant d'identifier et d'analyser des protéines et d'autres molécules biologiques produites par des cellules et/ou un tissu, notamment des cellules et/ou un tissu humains. L'invention concerne enfin une pluralité de membranes préparées et/ou traitées de manière différente, ces membranes pouvant être utilisées dans les procédés selon l'invention et permettant d'identifier et d'analyser des biomolécules.
Patent CA-2428708-A1 (CA)
Inventor: NIKNAFS HASSAN S
IPC: B01J19/30
Filed: 2001-11-06
Abstract: The invention provides a novel improved packing element having the basic shape of a polygon with arches (3) formed around the periphery by deforming the edge area in one direction and an area axially within the edge area to form arches (5) projecting in the opposite direction and providing an axially located aperture. Such packing elements can be conveniently formed using a simple cutting and stamping operation.
Patent CA-2430437-A1 (CA)
Title: Method of retrieving entities
Inventor: CRABTREE IAN BARRY
IPC: G06F17/30
Filed: 2001-12-11
Abstract: The present invention relates to a method of retrieving points that can be plotted in a predetermined area, where the locations of the points are indexed in an index that comprises regional data. The regional data defines a plurality of regions, and each region encompasses one or more of the points.  In addition, the index comprises linking data, which, for each region, identifies the point or points encompassed by that region. The method comprises the steps of:(i) reviewing the regional data in the index to identify regions that are wholly contained by the predetermined area; and(ii) reviewing the linking data to retrieve points encompassed by the identified regions.
Patent CA-2431444-A1 (CA)
Title: Multi-level stacking container
Inventor: RAGHUNATHAN NARAYAN
IPC: B65D21/06
Filed: 2003-06-09
Abstract: The present invention provides a container comprising a base configured to vertically support at least one object, a pair of opposed sidewalls projecting above the base and configured to retain the at least one vertically supported object on the base, each of the sidewalls having a top surface, an exterior surface, and a receptacle, wherein the exterior surface merges with the top surface to define an upper exterior edge, and wherein the exterior surface further merges with the receptacle to define a receptacle edge, and a support member pivotally mounted within the receptacles to facilitate pivotal movement of the support member relative to each of the sidewalls, the support member being configured to support a second identical container, wherein the upper exterior edge and the receptacle edge of at least one of the opposed sidewalls are configured to simultaneously oppose the support member during at least a portion of the pivotal movement such that the clearance between the support member and the upper edge is greater than the clearance between the support member and the receptacle. The present invention provides a container comprising a base configured to vertically support at least one object, a pair of opposed sidewalls and a pair of opposed endwalls, each of the sidewalls and the endwalls projecting above the base and configured to retain the at least one vertically supported object on the base, each of the sidewalls having an exterior surface defining a receptacle, and a support member pivotally mounted within the receptacles to facilitate pivotal movement of the support member relative to each of the sidewalls, the support member configured to support a second identical container, wherein at least one of the endwalls includes a support surface configured to support the support member, the support surface including at least two notches configured to permit application of a force to the support member by fingers of a human hand when the support member is resting on the support surfaces such that the application of the force displaces the support member from the support surface.
Patent CA-2431725-A1 (CA)
Title: Relocating context information in header compression
Inventor: KALLIOKULJU JUHA
IPC: G06F15/16
Filed: 2002-01-09
Abstract: A method of relocating the header compression context in a packet network which transmits packets having compressed headers. A connection is established between a mobile terminal and a first network entity and context information used with compression and decompression of the headers of the packets is stored at the mobile terminal and the first network entity. The context information updating is stopped in the mobile terminal and in the first network entity and after that, a snapshot of the compression and decompression context information is taken and stored in the first network entity. The connection between the first network entity and the mobile terminal is changed to a connection between the mobile terminal and a second network entity. The context information snapshot stored by the first network entity is transferred to the second network entity to be stored therein as the context information of the second network entity. The stored context information at the mobile terminal and the second network entity is then used for compression and decompression of the headers of the packets.
Patent CA-2432203-A1 (CA)
Title: Sustained release drug delivery devices with multiple agents
Inventor: PAPADOPOULOS PAVLOS
IPC: A61F9/00
Filed: 2001-12-27
Abstract: The present invention is directed to an improved sustained release drug delivery device for delivering multiple agents comprising a drug core, a unitary cup, and a permeable plug.
Patent CA-2435826-A1 (CA)
Title: Differentiation of stem cells to pancreatic endocrine cells
Inventor: MC KAY RONALD D
IPC: A61K35/12
Filed: 2002-01-24
Abstract: A method is provided for differentiating embryonic stem cells to endocrine cells. The method includes generating embryoid bodies from a culture of undifferentiated embryonic stem cells, selecting endocrine precursor cells, expanding the endocrine precursor cells by culturing endocrine cells in an expansion medium that comprises a growth factor, and differentiating the expanded endocrine precursor cells in a differentiation media to differentiated endocrine cells produced by this method are also provided.  Artificial islets are disclosed, as well as method for using the pancreatic endocrine cells and the artificial islets.
Patent CA-2437601-A1 (CA)
Title: Method for cold rolling metals using an aqueous lubricant comprising at least a carboxylic acid, a phosphate ester and a wax
Inventor: RAISON DOMINIQUE
IPC: C10M171/06
Filed: 2002-02-05
Abstract: The invention concerns a method for cold rolling metals using an aqueous lubricant comprising: (1) at least a mixture based on at least an acid selected among saturated or unsaturated mono- or poly-carboxylic acids, comprising 5 to 40 carbon atoms; at least an acid phosphate ester of formula (RO)¿x?-P(=O)(OH)¿x'?, wherein: R is a hydrocarbon radical, optionally polyalkoxylated; x and x' being equal to 3; the carboxylic acid and/or the acid phosphate ester being optionally neutralised by an organic or mineral base; and (2) at least a natural or synthetic wax exhibiting a melting point not less than 50 ·C and having an average particle size ranging between 0.5 and 10 µm. The use of said lubricant enables to increase the productivity of the method by at least 15 % relative to a method using a conventional lubricant.
Patent CA-2440222-A1 (CA)
Inventor: LETAVIC MICHAEL ANTHONY
IPC: C07D471/04
Filed: 2002-02-08
Abstract: The present invention relates to novel triazolo-pyridines of the formula I  wherein Het is an optionally substituted 5-membered heterocycle containing one to two heteroatoms selected from nitrogen, sulfur and oxygen wherein at least one of said heteroatoms atoms must be nitrogen; R2 is selected from the group consisting of hydrogen, (C1-C6) alkyl or other suitable substituents; R3 is selected from the group consisting of hydrogen, (C1-C6)alkyl or other suitable substituents; s is an integer from 0-5; to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the present invention are potent inhibitors of MAP kinases, preferably p38 kinase. They are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, repurfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
Patent CA-2443129-A1 (CA)
Inventor: PRESSMAN LORI
IPC: G02B6/036
Filed: 2002-04-12
Abstract: The invention features high index-contrast fiber waveguides (1301) that can be drawn from a preform. The invention also features materials for forming high index-contrast fiber waveguides (1301), and guidelines for their selection.  High index-contrast fiber waveguides (1301), which may include opical fibers and photonic crystal fibers, can provide enhanced radial confinement of an optical signal in the fiber waveguide (1301). Moreover, large optical energy densities can be achieved inside the high index-contrast fiber waveguides, making them attractive candidates for a number of applications.
Patent CA-2444668-A1 (CA)
Title: Method of providing a phosphorescent coating system through wet-on-wet application and a phosphorescent coating system thereof
Inventor: JAKOBI MICHAEL
IPC: C09D5/22
Filed: 2002-05-20
Abstract: A phosphorescent coating system and a method of providing the coating system on a substrate are disclosed. The method includes applying a color-providing composition, such as a pigmented basecoat composition, and applying a clearcoat composition. After application and cure, the color-providing composition forms a color-providing film layer, and the clearcoat composition forms a clearcoat film layer. The color-providing composition and the clearcoat composition are cross-linkable. Either one, or both, of the color-providing composition and the clearcoat composition include phosphorescent pigment. The color-providing composition is applied to the substrate to form an uncured film layer of the color-providing composition. Next, the clearcoat composition is applied wet-on-wet to the uncured film layer of the color-providing composition such that an uncured film layer of the clearcoat composition is formed on the uncured film layer of the color-providing composition.
Patent CA-2445598-A1 (CA)
Title: Methode et appareil de modelisation mathematique des diabetes
Inventor: HALL KEVIN
IPC: G16B5/10
Filed: 2002-04-29
Abstract: La présente invention concerne généralement un modèle mathématique et informatique de troubles afférents aux diabètes (par exemple, les diabètes humains de type 2) à l'intérieur du cadre du métabolisme à macronutriants multiples. Ce modèle comprend une représentation des mécanismes de régulation physiologique complexe dirigeant, par exemple, un métabolisme lipidique, un métabolisme protéique, et/ou un métabolisme glucidique. Dans un mode de réalisation, par exemple, le modèle peut prendre en compte l'interconversion entre des macronutriants, ainsi que leur digestion, leur absorption, leur stockage, leur mobilisation et leur utilisation adaptative, et la régulation endocrinienne de ces processus. Dans ce mode de réalisation, on peut simuler le modèle, par exemple, un groupe hétérogène des troubles afférents aux diabètes, à partir d'insuline résistant au diabète grave, et on peut prévoir les effets probables des interventions thérapeutiques.
Patent CA-2447565-A1 (CA)
Inventor: DEWEY CHARLES H
IPC: E21B23/04
Filed: 2003-10-31
Abstract: A lockable motor assembly for use in a well bore comprises a stator, a rotor rotatably mounted within the stator, and a selectively removable flow restriction means. The lockable motor assembly may further comprise holding means for rotationally fixing the rotor to the stator. The flow restriction means limits the flow rate of fluid downstream of the rotor, thereby substantially balancing hydraulic pressure above and below the stator.
Patent CA-2449510-A1 (CA)
Inventor: ILIUK ANDREY
IPC: E05B63/00
Filed: 2002-06-28
Abstract: A morticle lock for recessed installation into the edge of a door or door frame. Various inventive features include> (a) a deadlatching member moun ted on the bolt assembly, for pivoting movement, (b) the drive shaft (& hub) can be rotated in either a clockwise or anticlockwise direction to cause bolt retraction, (c) the drive shaft (& hub) can be locked against rotation o r not, by a locking means mechanically connected to the cylinder cam rotated by a key, (d) the drive shaft (& hub) can be locked against rotation or not, by a locking means mechanically connected to an assembly comprising, the bolt assembly interacting with a separately activated kick off member, such that on retraction of the bolt, depending on the position of the kick off member, th e hub is locked against rotation, (e) the bolt can be retracted by each of the key cylinder cam and the hub, in isolation.
Patent CA-2452270-A1 (CA)
Title: Method and devices for controlling loads connected to a power line
Inventor: VAN TICHELEN PAUL
IPC: H04B3/54
Filed: 2002-06-26
Abstract: The present invention is related to a method and devices for controlling at least one load connected to an AC power line. The method is based on the introduction of interruptions in the line voltage, which correspond to data being sent. The method centres on interruptions of variable length, yielding the opportunity of sending more data with a reduced number of interruptions. The invention is further related to a particular design of the transmitter a nd receiver. The transmitter is equipped with a means for measuring the line current. The receiver is equipped with a comparator with a feedback connection. The receiver is also capable of increasing momentarily the line current, which creates the possibility of sending information back towards t he transmitter.
Patent CA-2453612-A1 (CA)
Inventor: SEELEMANN DIRK A
IPC: G06F3/00
Filed: 2003-12-17
Abstract: There is provided a method and system for developing a transformation program to transform a data structure from a first format to a second format, the program including a plurality of coupled data transformation modules describing the transformation, the method comprising the steps of: generating a first transformation module of the plurality of transformation modules for assembling the program, the first module being a module type of a set of module types including a language constructed module type and a visually constructed module type;  extracting reference information from the first module for accessing the first module when stored in a memory; and updating a module registry to include a first entry corresponding to the reference information of the first module, the module registry configured for having reference information entries extracted from both the language constructed modules and visually constructed modules.
Patent CA-2454702-A1 (CA)
Title: Novel compounds
Inventor: GRIFFITHS DAVID
IPC: A61K31/381
Filed: 2002-07-19
Abstract: The invention relates to thiophene carboxamides of formula (I),wherein R1, R 2, R3, A, n and X are as defined in the specification, processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy.
Patent CA-2457477-A1 (CA)
Inventor: CHEN WEN
IPC: A23L7/104
Filed: 2002-08-27
Abstract: La présente invention concerne des polynucléotides, de préférence des polynucléotides synthétiques, qui codent les enzymes de maturation optimisés pour une expression dans les plantes. Ces polynucléotides codent des enzymes de maturation mésophiles, thermophiles ou hyperthermophiles, qui sont activées sous des conditions d'activation appropriées, de façon à agir sur le substrat désiré. L'invention concerne également des plantes transgéniques qui se mûrissent d'elles-mêmes, et des parties de plantes, notamment le grain, qui exprime l'une au moins de ces enzymes et présente une composition modifiée qui favorise le mûrissement de la plante et du grain. L'invention concerne enfin des procédés pour faire et utiliser ces plantes, par exemple pour produire des produits alimentaires dont le goût a été amélioré, et pour produire des substrats fermentables se prêtant à la production d'éthanol et de boissons fermentées.
Patent CA-2457671-A1 (CA)
Title: Process for the preparation of a 14-hydroxynormorphinone derivative
Inventor: LINDERS JOANNES THEODORUS MARI
IPC: C07B61/00
Filed: 2002-08-15
Abstract: The present invention relates to process for the preparation of a 14- hydroxynormorphinone derivative of formula (IV) comprising reacting the compound of formula (III), with a cobalt (II) oxidant in the presence of a mild base and air or oxygen as the cooxidant; wherein R1 is (1C-7C) alkyl optionally substituted with one or more chlorines, butenyl, vinyl, benzyl, phenyl or naphthyl; and R2 is benzyl or benzyl substituted with one ore more (1C-6C) alkoxy group or benzyl substituted with one or more halogen. The process is very suitable in the production of noroxymorphone.
Patent CA-2458488-A1 (CA)
Inventor: OBLACK MARK
IPC: A01K15/02
Filed: 2004-02-24
Abstract: A pet toy particularly designed for a pet for playing fetch and pulling. The pull toy includes a plurality of woven strands securing attached to a head. The head includes an opening through a portion of the strands remains secured to the head, the remaining portion of the strands extend out the opening and are of sufficient length to be grabable by a person or pet. The woven strands may be a rope body having a torso having arms and legs with an optional knot at the distal ends of the amps and legs, In other embodiments the woven strands may form an elongated strap with or without an handle, or a head having individual strands extending from the head. In the preferred attachment, the opening of the head is divided by a rib to form two compartments. The woven strands can be positioned about the rib with apex of the strands abutting one end of the rib and remaining portions positioned on either side of the rib through the two compartments and out through the opening to extend past the head.
Patent CA-2459936-A1 (CA)
Title: Building wall element
Inventor: DINCEL BURAK
IPC: E04C2/34
Filed: 2002-10-10
Abstract: An elongated building element (14) to form a series of walls (10) to (13). The elements (14) each have longitudinally extending flanges (21) that snap engage with longitudinally extending grooves (19) in the next adjacent element (14).  Accordingly the wall (10) is constructed by joining the elements (14) in a direction transverse their general direction of extension. If so required the elements (14) may be filled with concrete.
Patent CA-2460114-A1 (CA)
Inventor: MARTIN MARK
IPC: G01N33/68
Filed: 2002-09-10
Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.
Patent CA-2460170-A1 (CA)
Title: Appareil a laser multi-longueur d'onde et procede
Inventor: SALCEDO JOSE R
IPC: H01S3/137
Filed: 2002-09-13
Abstract: L'invention concerne une source laser à fibre optique capable d'émettre de multiples longueurs d'ondes utiles en même temps, notamment de multiples longueurs d'onde de grille UIT. Le laser comprend de préférence un amplificateur à fibre dopée par terres rares pompé par diode en tant que milieu de gain, un filtre périodique destiné à définir un premier ensemble de longueurs d'ondes de laser possibles correspondant à des longueurs d'onde de laser de grille UIT, et un filtre à résonance destiné à définir un sous-ensemble du premier ensemble de longueurs d'ondes. L'agencement est contenu dans un résonateur annulaire. Le résonateur annulaire peut être constitué, en partie ou en totalité, de fibre optique maintenant la polarisation. Le résonateur peut également comprendre des isolateurs optiques en ligne afin d'assurer un fonctionnement unidirectionnel et d'éliminer les réflexions indésirables. Un filtre d'aplatissement du gain peut aussi être ménagé dans le résonateur selon les caractéristiques de sortie voulues du laser. Le laser peut être conçu pour fonctionner dans un ensemble de modes longitudinaux monocavité. Le laser de l'invention peut également comprendre une commande de définition et de stabilisation de longueur d'onde et/ou de puissance de sortie.
Patent CA-2460382-A1 (CA)
Inventor: CHEN STEPHEN
IPC: B41J2/175
Filed: 2004-03-09
Abstract: A high capacity ink supply apparatus and particular an ink supply apparatus for inkjet printers mainly includes a high capacity tank, a duct and an ink cartridge. The high capacity tank has an air intake device to receive air and a check valve to allow the ink to flow in one direction. The ink cartridge is formed in a standardized fashion to be housed in a core trough of an imitated outer cartridge which is compatible with the original ink cartridge of a corresponding brand. Such a structure can increase ink storage capacity and reduce ink utilization cost and improve the applicability for various brands.
Patent CA-2461067-A1 (CA)
Inventor: HANATANI MINORU
IPC: C09D5/44
Filed: 2004-03-09
Abstract: A coating film-forming method, which method comprises coating a cationic electrodeposition coating composition onto a substrate, followed by heat curing to form a cured electrodeposition coating film, said cationic electrodeposition coating composition containing a base resin consisting of an amine-added epoxy resin (A) obtained by reacting an epoxy resin (a1) with at least one modifying agent selected from the group consisting of a polyhydric polyol (a2), an epoxy compound (a3) of the polyhydric polyol and a cyclic ester compound (a4), a polyphenol compound (a5) and an amino group-containing compound (a6), and a curing agent consisting of a blocked polyisocyanate curing agent (B) obtained by reacting at least one polyisocyanate compound (b1) selected from the group consisting of an aromatic polyisocyanate compound and an alicyclic polyisocyanate compound with at least one blocking agent (b2) selected from the group consisting of an oxime compound, aliphatic alcohols, aromatic alkyl alcohols and ether alcohols.
Patent CA-2462537-A1 (CA)
Title: Method for preparing a compound for interaction of active substances with a porous support using supercritical fluid
Inventor: JOUSSOT-DUBIEN CHRISTOPHE
IPC: A61K31/5415
Filed: 2002-10-11
Abstract: The invention concerns a method for preparing compounds for interaction of an active substance hardly soluble in an aqueous medium with a porous support. The invention is characterized in that it comprises the following steps: (a) mixing the active substance generated by supercritical fluid and the specific amount of porous support; (b) carrying out a molecular diffusion step by contacting in static mode a supercritical fluid with the mixture obtained at step (a) for the time required to improve the dissolution in the aqueous medium of the mixture obtained at step (a); (c) washing the interactive compound obtained at step (b) with a supercritical fluid flow; (d) recuperating the particles of the interactive compound thus formed. The invention also concerns a compound obtainable by said method.