baber/WOPTO huggingface dataset:
Patent CA-2986830-A1 (CA)
Inventor: NGUYEN TUAN HUY
IPC: C12N5/071
Filed: 2016-02-19
Abstract: The invention relates to the use of a laminin (LN) as a matrix for hepatic differentiation. The invention also relates to a method for inducing hepatic differentiation comprising the steps of: (i) providing a population of human pluripotent cells, (ii) culturing the population on a support coated with a laminin in a endoderm induction medium to produce a population of human DE cells, (iii) culturing said population of human DE cells on a support coated with a laminin in a hepatic induction medium to produce a population of human hepatoblasts-like cells, and (iv) optionally culturing said population of human hepatoblasts-like cells on a support coated with a laminin in a hepatic maturation medium to produce a population of human hepatocyte-like cells. The invention further relates to a population of human hepatoblasts-like cells or human fetal hepatocyte-like cells obtained by the method of the invention. The invention further relates to a population of human hepatoblasts-like cells expressing HNF4 a and expressing substantially AFP for use in a method of treatment of the human body.
Patent CA-2987799-A1 (CA)
Title: Skid structure for underwater seismic exploration
Inventor: FYFFE ROGER L
IPC: B63B27/00
Filed: 2017-03-30
Abstract: The present disclosure is directed to a skid structure for underwater seismic exploration. The system can include an underwater vehicle comprising a skid structure. A conveyor is provided in the skid structure. The conveyor includes a first end and a second end opposite the first end. A capture appliance is provided at the first end of the conveyor. The capture appliance includes an arm to close to hold a case storing one or more ocean bottom seismometer ("OBS") units, and to open to release the case. The capture appliance includes an alignment mechanism to align an opening of the case with the first end of the conveyor. A deployment appliance can be at the second end of the conveyor. The deployment appliance can place an OBS unit of the one or more OBS units onto the seabed to acquire seismic data from the seabed.
Patent CA-2989046-A1 (CA)
Inventor: BARROWS COREY KENNETH
IPC: A61F2/16
Filed: 2017-12-14
Abstract: The present disclosure relates to sensor systems for electronic ophthalmic devices. In certain embodiments, the sensor systems may comprise a first electrode configured to be selectively overlaid by one or more of an upper eyelid and a lower eyelid of a user, a second electrode configured to be selectively overlaid by one or more of an upper eyelid and a lower eyelid of a user, and a system controller cooperatively associated with the first electrode and the second electrode to receive a capacitance measurement therefrom, the system controller configured to determine a position of one or more of the upper eyelid and the lower eyelid in spatial coordinates based on the capacitance measurement received from the first electrode and the second electrode.
Patent CA-2989207-A1 (CA)
Title: Poignee de valise telescopique
Inventor: SCICLUNA PAUL V
IPC: A45C13/30
Filed: 2016-07-01
Abstract: L'invention concerne une poignée de valise télescopique comprenant un logement de poignée télescopique disposé à l'intérieur d'une valise, une section de poignée extensible inférieure, disposée de manière mobile à l'intérieur du logement de poignée télescopique, et une section de poignée extensible supérieure, disposée de manière mobile à l'intérieur de la section inférieure. Une goupille à ressort disposée à l'intérieur de la section supérieure se met en prise, de manière libérable, avec l'une d'une pluralité d'ouvertures le long de la longueur de la section inférieure afin de maintenir temporairement la section de poignée extensible supérieure en place. Un élément saillant à ressort se met en prise, de manière libérable, avec la section de poignée extensible inférieure afin de maintenir temporairement la section inférieure en place.
Patent CA-2990210-A1 (CA)
Inventor: KOZIARA JOANNA M
IPC: A61K9/24
Filed: 2016-06-29
Abstract: L'invention concerne une forme galénique orale solide comprenant du ténofovir alafénamide ou un sel pharmaceutiquement acceptable de celui-ci, et de l'emtricitabine ou un sel pharmaceutiquement acceptable de celle-ci.
Patent CA-2992064-A1 (CA)
Title: Alkenylphenoxy-substituted 1,1-diphenylethylenes, processes for their preparation, and their use
Inventor: EVSYUKOV SERGEY
IPC: C08G73/12
Filed: 2016-09-02
Abstract: The present invention relates to compounds according to formula (I) and to heat-curable compositions based on polymaleimide resin systems comprising such compounds as co-monomers: wherein R1 is hydrogen or an alkenylphenoxy group, R2 is an alkenylphenoxy group, and R3 is hydrogen or an alkyl group with 1 to 4 carbon atoms. The present invention also relates to crosslinked resins obtainable by curing such compositions. Compounds of the present invention can be used amongst others in fields like structural adhesives, matrix resins for fiber prepregs, moulding compounds, as well as structural and/or electrical composites.
Patent CA-2993757-A1 (CA)
Title: Suspension avant de vehicule a moteur
Inventor: RAFFAELLI ANDREA
IPC: B62K5/10
Filed: 2016-07-28
Abstract: L'invention concerne un train avant de véhicule à moteur (8) comprenant un châssis (16) de train avant, une paire de roues avant (10', 10") reliées par voie cinématique au châssis (16) de train avant au moyen d'un quadrilatère articulé, comprenant une paire d'éléments transversaux, articulé sur le châssis (16) de train avant de façon correspondante avec des charnières intermédiaires, lesdits éléments transversaux étant reliés ensemble, de façon correspondante avec des extrémités transversales opposées, au moyen de montants amenés à pivoter vers lesdites extrémités transversales de façon correspondante avec des charnières latérales, chacun des montants guide et supporte un demi-essieu d'une roue avant (10', 10") relié par voie mécanique à une broche de rotation de la roue avant (10', 10"), chaque montant s'étendant depuis une extrémité supérieure vers une extrémité inférieure et chaque broche de rotation de la roue avant (10', 10") étant comprise entre l'extrémité supérieure et l'extrémité inférieure du montant correspondant.
Patent CA-2995760-A1 (CA)
Title: Marqueur de croissance compacte du concombre
Inventor: VAN DER LINDE LILIAN
IPC: C12Q1/68
Filed: 2016-09-08
Abstract: La présente invention concerne un marqueur permettant d'identifier un plant de concombre présentant un phénotype de croissance compacte, caractérisé par une longueur internud plus courte et/ou une surface foliaire plus petite. Le marqueur comprend une mutation du gène Cullin1, ce qui donne des plants de concombre ayant une longueur internud plus courte et/ou une surface foliaire plus petite que les plants de concombre sans la mutation du gène Cullin1. Un plant présentant ce phénotype de croissance compacte ainsi obtenu est particulièrement approprié pour la culture suspendue. L'invention concerne en outre l'utilisation d'un gène Cullin1 de concombre modifié, ou d'une partie de celui-ci, pour identifier un plant de concombre présentant une longueur internud plus courte et/ou une surface foliaire plus petite.
Patent CA-3002150-A1 (CA)
Title: Tubage d'emplacement de forage a couplage integre et son procede de fabrication
Inventor: MOURRE DARREN EDWARD
IPC: E21B17/08
Filed: 2016-10-14
Abstract: L'invention concerne un joint de tubage intégré, un ensemble tubage et un procédé. Le tubage intégré comprend une partie tubulaire et une paire d'extrémités de joint tubulaire. La paire d'extrémités de joint tubulaire peuvent être positionnées au niveau d'extrémités opposées de la partie tubulaire. Au moins une parmi la paire d'extrémités de joint tubulaire comprend une extrémité refoulée, formée en une seule pièce avec la partie tubulaire. L'extrémité refoulée possède une résistance mécanique équivalente à celle de la partie tubulaire, et peut être reliée de manière correspondante à l'une de la paire d'extrémités de joint tubulaire d'un joint de tubage adjacent pour définir un raccordement de tubage intégré entre elles, l'efficacité du tubage étant ainsi optimisée.
Patent CA-3005038-A1 (CA)
Inventor: POST NICHOLAS JON
IPC: A61B34/30
Filed: 2016-11-03
Abstract: A robotic surgical systems and methods of operating the same are provided. The system comprises a surgical tool, a manipulator having a plurality of joints and supporting the surgical tool, and a controller. A virtual simulation represents the surgical tool as a virtual rigid body having a virtual mass including an inertia about at least one of the j oints. The controller determines an expected joint torque for the joint. The expected joint torque is compared to an actual joint torque of the joint to determine a joint torque difference. The inertia of the virtual mass about the joint is determined. An angular acceleration about the joint is computed using the joint torque difference and the inertia. The angular acceleration is projected to the virtual mass to determine an external force. The controller simulates dynamics of the surgical tool in the virtual simulation in response to the external force.
Patent CA-3005841-A1 (CA)
Title: Artificial mycolic acid membranes
Inventor: GUNDLACH JENS H
IPC: C12Q1/00
Filed: 2011-02-23
Abstract: Provided herein are artificial membranes of mycolic acids. The membranes may be unsupported or tethered. These membranes are long lived and highly resistant to electroporation, demonstrating their general strength. The mycolic acid membranes are suitable for controlled studies of the mycobacterial outer membrane and can be used in other experiments, such as nanopore analyte translocation experiments.
Patent CA-3007482-A1 (CA)
Title: Multifunctional superhydrophobic particles for chemical adhesion and blooming
Inventor: VENEMA PETER CRAIG
IPC: C07F7/08
Filed: 2015-12-07
Abstract: Provided herein is a multifunctional particle and methods of forming the same. The multifunctional particle includes a surface of the particle; a first moiety coupled to the surface and having at least one substantially hydrophobic appendage; and a second moiety coupled to the surface and having at least one appendage comprising a reactive functional group and a substantially hydrophilic repeating unit, whereby the particle is substantially superhydrophobic as a result of the substantially hydrophobic appendage, chemically reactive as a result of the reactive functional group, and migratory to a surface of a substantially hydrophobic matrix in which the particle may be included as a result of the substantially hydrophilic repeating unit. Additionally, antimicrobial functional groups may be coupled to the surface.
Patent CA-3011092-A1 (CA)
Inventor: BRODERICK JAMES
IPC: A61K39/395
Filed: 2017-01-12
Abstract: The present application provides compositions and methods for treating a patient with cancer, and in particular epithelial tumors and carcinomas, with antibodies directed to CD33- like Siglecs.
Patent CA-3011094-A1 (CA)
Inventor: ERPELDING BEN
IPC: F24F11/76
Filed: 2017-01-12
Abstract: An environmental control system for a building in a geographic location and having a heating, ventilation and air-conditioning (HVAC) system includes at least one computer-readable medium having instructions stored thereon that, when executed by at least one processing device in communication with the external application, enables the at least one processing device to receive weather data characterizing a weather forecast over a predetermined time period for the geographic location, receive free-cooling window data, determine, based on the weather data and free-cooling window data, an available free-cooling time window, and issue to the external application an executable command to the HVAC system to enter free-cooling mode during the available free-cooling time window.
Patent CA-3014375-A1 (CA)
Inventor: BROOKES RUSSELL
IPC: G01L19/08
Filed: 2018-08-16
Abstract: A system, method, and device for monitoring one or more sensors at a remote location. The system allows a user to register multiple sensors to the user's account. When the sensors are deployed at a remote location for measuring various properties of their surrounding environments, they collect data which is then transmitted to a server. The user may then monitor the data by connecting to the server via a client device, and receive alerts when the data satisfies certain conditions.
Patent CA-3019012-A1 (CA)
Title: Procedes d'utilisation de (2r, 6r)-hydroxynorketamine et de (2s,6s)-hydroxynorketamine dans le traitement de la depression, de l'anxiete, de l'anhedonie, de l'ideation suicidaire et de troubles de stress post-traumatiques
Inventor: WAINER IRVING
IPC: A61K31/135
Filed: 2017-03-27
Abstract: La présente invention concerne un procédé de traitement d'une dépression psychotique, d'une idéation suicidaire, d'un trouble disruptif avec dysrégulation de l'humeur, d'un trouble dépressif persistant (dysthymie), d'un trouble dysphorique prémenstruel, d'un trouble dépressif induit par substance/médicament, d'un trouble dépressif dû à un autre état pathologique, d'un autre trouble dépressif spécifique, d'un trouble dépressif non spécifique, d'un trouble de l'anxiété de séparation, d'un mutisme sélectif, d'une phobie spécifique, d'un trouble d'anxiété sociale (phobie sociale), d'un trouble de panique, d'une attaque de panique (spécificateur), de l'agoraphobie, d'un trouble d'anxiété généralisée, d'un trouble dl'anxiété induit par substance/médicament, d'un trouble d'anxiété dû à un autre état pathologique, d'un autre trouble de l'anxiété spécifique, d'un trouble d'anxiété non spécifique, ou de la fatigue, le procédé comprenant l'administration d'une composition pharmaceutique contenant une quantité active d'un agent actif, l'agent actif étant de la (2R,6R)-hydroxynorkétamine purifiée, de la (2S,6S)-hydroxynorkétamine purifiée, ou une combinaison de ceux-ci, ou un sel pharmaceutiquement acceptable de celui-ci, conjointement avec un vecteur pharmaceutiquement acceptable à un patient ayant besoin d'un tel traitement.
Patent CA-3020210-A1 (CA)
Title: Regulation aerodynamique de pales d'helice, de soufflante et d'eolienne avec des alesages et/ou une coupe et/ou un crantage
Inventor: CIRUS ROBERT
IPC: F04D29/38
Filed: 2018-10-10
Abstract: Une pale dhélice, une soufflante et une éolienne davion axial de faible charge caractérisées par le rapport daspect des pales faible; à proximité de lensemble des extrémités de pale, mais dans une distance appropriée, sont formées dans la pointe de chaque pale, qui sétend entre un côté pression et un côté aspiration, et un canal menant à lencoche formée à travers le corps de la pale entre les côtés. La distance entre lencoche et la pointe de la pale modifie le diamètre des pales de 1,2 % à 1,67 %, le long de la longueur de lencoche. Pendant lexploitation, lair sécoulant à travers cette ouverture élimine la turbulence formée à lextrémité des pales. Les vibrations en résonance survenant sur les pales et les éoliennes sont également réduites, ce qui étend la durée de vie des pales.
Patent CA-3022337-A1 (CA)
Title: In-situ chemistry stack for continuous glucose sensors
Inventor: RAO ASHWIN K
IPC: C12Q1/00
Filed: 2017-04-26
Abstract: Embodiments of the invention provide an in-situ polymerization technique for creating a glucose sensor chemistry stack. An analyte sensor comprises a crosslinked polymer matrix in contact with an electrode. The crosslinked polymer matrix is formed by exposing ultraviolet (UV) light to a polymer matrix mixture comprising a plurality of hydroxyethyl methacrylate (HEMA) monomers, one or more di-acrylate crosslinkers, one or more UV photoinitiators, and an oxidoreductase. The oxidoreductase is covalently linked to the crosslinked polymer matrix. In typical embodiments, the oxidoreductase is a glucose oxidase-acrylate bioconjugate. In one or more embodiments, the analyte sensor apparatus further comprises a glucose limiting membrane positioned over the crosslinked polymer matrix. The glucose limiting membrane is formed by exposing ultraviolet (UV) light to a glucose limiting membrane mixture comprising a plurality of hydroxyethyl methacrylate (HEMA) monomers, one or more di-acrylate crosslinkers, one or more UV photoinitiators, ethylene glycol, and water.
Patent CA-3024789-A1 (CA)
Inventor: SHUMATE JOHN LEWIS
IPC: B01D35/30
Filed: 2018-11-20
Abstract: A filter arrangement for an aquarium is disclosed. The filter arrangement can include a housing assembly, a pump assembly, a transfer tube assembly, and a valve assembly for controlling water flow through the transfer tube assembly. The transfer tube assembly can include a tube structure within which a valve body of the valve assembly is rotatably disposed. The tube structure can be formed from a first tube half mated to a second tube half to permanently secure the valve body within the tube structure. A valve operator can be connected to the valve body to advantageously allow a user to manipulate the flow of water through the transfer tube assembly. Control of water flow through the filter arrangement is beneficial for obtaining a desired water flow for a certain aquarium size and application and for reducing flow during certain periods, such as during feeding.
Patent CA-3026210-A1 (CA)
Title: Peptides servant a l'inhibition de la trypsine
Inventor: MCKINLEY SCOTT
IPC: C07K14/81
Filed: 2017-06-09
Abstract: L'invention concerne des peptides inhibant la trypsine. L'invention concerne également des compositions pharmaceutiques contenant ces peptides, ainsi que l'utilisation de ces peptides et compositions pharmaceutiques dans l'inhibition des enzymes trypsine.
Patent CA-3026392-A1 (CA)
Inventor: WARLICK JOHN F
IPC: A61B17/22
Filed: 2018-12-04
Abstract: A method of treating an infected implant by administering acoustic shock waves to an implant area or region encompassing an implantation, includes the steps of activating acoustic shock waves of an acoustic shock wave generator to emit acoustic shock waves and subjecting the implant area to acoustic shock waves stimulating the implant area or region. The emitted acoustic shock waves are focused or unfocused acoustic shock waves, or acoustic pressure waves, generated electrohydraulically, electromagnetically, radially, or via a piezo electric generating system.
Patent CA-3027420-A1 (CA)
Inventor: VASQUEZ-GOVEA ALEJANDRO DIZAN
IPC: G01S17/66
Filed: 2017-06-06
Abstract: The invention relates to an autonomously guided machine (10) comprising at least a steering body and a steering mechanism (13), said machine also comprising: a guide system (11) including an optical filter (17) which has a receiving surface exposed to the exterior and which can transmit light rays directed substantially in one direction and eliminate other light rays; a screen (18) that receives the filtered light; a digital camera (19) for capturing pixel resolution images of the screen (18); a pre-processing element for selecting the pixels corresponding to an incident planar laser beam received by the guide system (11), and filtered and projected onto the screen (18), and for generating a response detection image; a line generator for generating an estimate J of the coordinates of the detected lines based on the response detection image, involving the processing of the pixel columns pixels; and a locator which receives the estimate of the coordinates of the detected lines and calculates values representative of pixel columns based on said estimate and on parameters of the guide system (11), and subsequently calculates a distance yw from the guide system (11) to the planar laser beam in order to control the steering mechanism (13) so as to minimise this distance yw.
Patent CA-3028014-A1 (CA)
Inventor: HUANG ZHENHUA
IPC: A61P31/04
Filed: 2017-06-22
Abstract: La présente invention concerne une forme cristalline de 9-aminométhyle substutués des composés de tétracycline et un procédé de préparation associé, et en particulier une forme cristalline du composé représenté par la formule (I), un procédé de préparation d'une forme cristalline du composé représenté par la formule (I) et l'utilisation de la forme cristalline dans la préparation de médicaments pour le traitement et/ou la prévention de maladies infectieuses provoquées par des bactéries sensibles à la tétracycline et/ou des bactéries résistantes à la tétracycline.
Patent CA-3028597-A1 (CA)
Inventor: SBIANCHI FABIO
IPC: G06Q10/08
Filed: 2017-06-30
Abstract: L'invention porte sur un système informatique permettant la facturation dynamique d'assurance automobile. Un système informatique est décrit pour une facturation dynamique d'assurance de véhicule, comprenant un dispositif de stockage de données stockant des instructions et un processeur de données qui est configuré pour exécuter les instructions pour amener le système informatique à calculer des valeurs de risque associées à un ou plusieurs déplacements d'un véhicule sur la base, au moins en partie, de données télématiques associées au véhicule, et déterminer une valeur d'assurance sur la base, au moins en partie, des valeurs de risque.
Patent CA-3030543-A1 (CA)
Inventor: SEO INKWON
IPC: H04L1/00
Filed: 2018-04-24
Abstract: A method for receiving, by a terminal, downlink control information according to one embodiment of the present invention may comprise: receiving bundling information on REGs through upper-layer signaling; performing blind detection for PDCCH within a CORESET set on a plurality of OFDM symbols; and obtaining a DCI from the PDCCH. The terminal can: bundle, into one REG bundle, only REGs that are located on the same RB within the CORESET and correspond to other OFDM symbols, if the bundling information indicates a first value; bundle together, into one REG bundle, REGs that are located on the same RB within the CORESET and correspond to other OFDM symbols, as well as REGs that are located on another RB, if the bundling information indicates a second value; and perform blind detection for the PDCCH, assuming the same precoding for REGs which fall within the same REG bundle on the basis of a REG bundling result.
Patent CA-3033066-A1 (CA)
Inventor: AMOS DAVID
IPC: F16L53/00
Filed: 2017-08-03
Abstract: A wrapped heating assembly may be wrapped around a tubular member for heating the tubular member. The wrapped heating assembly includes an outer insulation sleeve and a pocketed heating system that is fixed to an inner surface of the outer insulation sleeve in a manner that forms longitudinal pockets that extend between a first end of the outer insulation sleeve and a second end of the outer insulation sleeve. One or more heater strips are each respectively inserted longitudinally into a corresponding one of the pockets, wherein heat is generated by the heater strips when electrical current flows through the heater strips for heating the tubular member in a wrapped position. Multiple wrapped heating assemblies may be daisy chained together by electrical connectors into a heating system with a single thermostat and linked to a single power source to accommodate a wide range of configurations of tubular member systems.
Patent CA-3033149-A1 (CA)
Inventor: BAWRI BINOD KUMAR
IPC: B28C5/00
Filed: 2016-12-28
Abstract: The present invention discloses a system and process for producing a variety of dry mix construction and ancillary construction materials (DMC) with improved structural properties. The said system and process employs a material classification unit (204) that classifies atleast one of plurality of raw materials (A, B, .. N) based on their particle size and physical properties. These classified raw materials are stored separately in material handling compartments (260) and are selected according to the construction grade requirements of the end user. The invention further involves the use of a material selection unit (210) which controls the functioning of various components of present invention. The said system and process also provides an easy means of reutilization of industrial waste products like fly ash, blast furnace slag to produce a variety of construction and ancillary construction materials.