baber/WOPTO huggingface dataset:
Patent DE-69013672-T2 (DE)
Inventor: CARLSSON PER
IPC: A61P25/00
Filed: 1990-01-03
Granted: 1995-03-30
Abstract: This invention is therapeutically useful tetralins and pharmaceutically acceptable acid addition salts thereof of formula (I), wherein X1 is halogen, CF3, -OR3, or -SR4; wherein R3 is alkyl(C1-C8); alkenyl(C1-C8), -CH2-cycloalkyl(C3-C8) or benzyl; wherein R4 is alkyl(C1-C3); wherein X2 is hydrogen, CF3 or halogen; wherein R7 is hydrogen or methyl; wherein R1 is hydrogen, alkyl(C1-C3), or cyclopropylmethyl; wherein R2 is -CH2-cycloalkyl(C3-C8), alkyl(C1-C8), -(CH2)q-R5 or -CH2CH2-Z-(CH2)rCH3; wherein R5 is phenyl, 2-thiophene or 3-thiophene; wherein Z is oxygen or sulfur; and wherein p is 1 or 2, q is 2 or 3, and r is 0 to 3; with the provisos that (1) when X1 is -OR3, X2 is halogen or CF3; and (2) when X1 is halogen, X2 is hydrogen, and p is 2, X1 is in a position other than the 8-position. These compounds are useful to treat central nervous system disorders.
Patent DE-69013677-T2 (DE)
Inventor: FAILLA CHARLES
IPC: F02F3/28
Filed: 1990-01-23
Granted: 1995-03-02
Abstract: A piston for a reciprocating piston internal combustion engine is provided with a reaction chamber (44, 144) communicating with a recessed area (42, 142) of the piston through a restricted continuous slot orifice (46, 146) that is configured to create a choked fluid flow condition between the combustion chamber (30, 130) and the reaction chamber at all engine operating speeds. Fuel is supplied to the reaction chamber and undergoes a controlled, cold frame reaction process while in intimate contact with the crown portion (54) of the piston (14). The reaction produces fuel radicals in sufficient quantity to seed subsequent fuel charges to properly condition the charge for predetermined desired ignition and combustion characteristics. The choking orifice (46, 146) ensures that outward flow of radicals from the reaction chamber is controlled to the extent that they will be maintained in the combustion chamber following an exhaust event of the combustion cycle so they will be available during a subsequent compression stroke of the piston for seeding the subsequent charge. The radical population in the subsequent charge conditions the charge to obtain dependable and predictable ignition in a compression ignition engine as well as knock free combustion at relatively lean air to fuel ratios in a spark ignited engine.
Patent DE-69015384-T2 (DE)
Inventor: FLAUGH MICHAEL EDWARD
IPC: A61K31/352
Filed: 1990-02-22
Granted: 1995-05-18
Abstract: The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes which exhibit binding activity at the serotonin 1A receptor and 3-aminochromane intermediates. The pharmaceutical compounds have the formula <CHEM>  in which R is C1-C4 alkyl, allyl, or cyclopropylmethyl; R1 is hydrogen, C1-C4 alkyl, allyl, cyclopropylmethyl, or aryl(C1-C4-alkyl);  R2 is hydrogen or methyl;  X is -CH2- or -O-; R3 is C1-C8 alkyl, aryl, substituted aryl, aryl(C1-C4-alkyl), substituted aryl(C1-C4 alkyl), or C5-C7 cycloalkyl;  n is 0, 1, or 2; and pharmaceutically acceptable acid addition salts thereof.
Patent DE-69015759-T2 (DE)
Inventor: LE BIHAN DENIS
IPC: H04L12/54
Filed: 1990-10-08
Granted: 1995-05-11
Abstract: The incoming cells of a input asynchronous time-division multiplex channel (mtr) are counted by a counter (FFB) assigned to each virtual circuit which is incremented on each incoming cell of the virtual circuit and decremented periodically. Clock signals define consecutively numbered cell times (ntc). Queue and chaining table (FAVE, FCVN) define a cell time queue (FAF, FAL, FAV) specific to each of the cell times, a virtual circuit being assignable to a cell time by writing its identifier into the corresponding cell time queue. A controller (MC) uses the content of the cell time queues (FAF, FAL, FAV) and, for each cell time, identifies a virtual circuit to be processed and decrements the counter (FFB) belonging to this virtual circuit. The controller further includes arrangements whereby any virtual circuit whose counter is not idle is assigned to one of the cell times to be decremented by virtue of the arrival of this cell time.
Patent DE-69016732-T2 (DE)
Inventor: GERVAIS CHRISTIAN
IPC: C07K5/06
Filed: 1990-09-28
Granted: 1995-06-01
Abstract: Process for solubilising peptide in a water-immiscible organic solvent, consisting in bonding a lipophilic group to the terminal carboxylic group of the said peptide via an amide or ester bond; this lipophilic group is characterised in that when it is bonded to L-serine a molecule is obtained whose solubility in water at 25 DEG C is lower than 30 g/litre. This lipophilic group is chemically defined and nonpolymeric. The invention also relates to a process for the synthesis of optionally protected peptides, in liquid medium, characterised in that it starts with an amino acid or a peptide solubilised in organic medium by a lipophilic A-L group bonded to the carboxylic functional group of the starting amino acid or peptide and in that the amino acids or the peptides to be condensed, which are activated on their acidic functional group and protected on their amine functional group and optionally on their side chain, are added. The peptides originating from the synthesis are optionally employed for the synthesis of medications, vaccines and agri-foodstuffs or plant protection products.
Patent DE-69024806-T2 (DE)
Inventor: EKETORP RAINER
IPC: C07K16/06
Filed: 1990-06-20
Granted: 1996-05-23
Abstract: A method is provided for cleansing a protein from multivalent metal ions bound thereto, these ions being released from the protein by exchanging the ions with monovalent metal ions, whereafter the multivalent metal ions are removed. The release and removal of these ions is effected, in particular, by diafiltration or gel filtration processes.
Patent DE-69102288-T2 (DE)
Inventor: YOUDIM MOUSSA B H
IPC: C12N9/99
Filed: 1991-01-02
Granted: 1995-02-09
Abstract: R-(+)-N-propargyl-1-aminoindane of formula (I) and its pharmaceutically acceptable acid addn. salts are new. (I) is prepd. by reacting R(-)-1-aminoindane with propargyl bromide or chloride in the presence of base (and opt. of solvent), then (I) is isolated by e.g. chromatography, distn. or selective extraction. The racemic starting material can be used instead and (I) then recovered by fractional crystallisation of salts formed with an optically active acid.
Patent DE-69103035-T2 (DE)
Inventor: BRISSONNEAU PIERRE
IPC: C21D8/12
Filed: 1991-01-28
Granted: 1995-03-23
Abstract: The process for aluminising a sheet of magnetic steel with oriented grains which has been subjected to at least one cold rolling, at least one intermediate annealing under hydrogen atmosphere, followed by a decarbonising annealing, the grains of the sheet being then in the primary recrystallisation state, is characterised in that a deposition of aluminium is carried out on the said sheet between two stages of a final annealing, the first stage of which produces a partial or total secondary recrystallisation of the grains of the sheet and the second stage of which allows the aluminium to diffuse and the impurities to be removed. 
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Patent DE-69111792-T2 (DE)
Inventor: SZITA JENO G
IPC: C09D167/00
Filed: 1991-10-29
Granted: 1995-11-30
Abstract: Sulfonimide cure catalysts are used with aminoplast crosslinking agents and resins capable of reacting with aminoplast crosslinking agents to prepare heat curable compositions capable of crosslinking to form coatings and articles. Liquid or solid curable compositions may be prepared. Solid sulfonimide catalysts used in combination with solid glycoluril type crosslinking agents are well suited for powder coating systems containing hydroxy- and carboxy-functional resins.
Patent DE-69123981-T2 (DE)
Inventor: GUILD BRAYDON
IPC: A61K35/44
Filed: 1991-10-31
Granted: 1997-06-05
Abstract: Retroviral vectors are disclosed which include an insertion site for genes of interest and are capable of expressing high levels of the protein derived from the genes of interest in a wide variety of transfected cell types. Also disclosed are retroviral vectors lacking a selectable marker, thus rendering them suitable for human gene therapy in the treatment of a variety of disease states without the co-expression of a marker product, such as an antibiotic. These retroviral vectors are especially suited for use in certain packaging cell lines.
Patent DE-69131258-T2 (DE)
Inventor: HANYU YUKIO
IPC: G02F1/141
Filed: 1991-03-01
Granted: 2000-03-02
Abstract: A ferroelectric liquid crystal element comprises a ferroelectric liquid crystal and a pair of substantially parallel substrates having opposite surfaces between which the ferroelectric liquid crystal is sealed. The substrates are provided with electrodes to which voltages are applied, and are subjected to one axis parallel orientation treatment (A) so as to orient the ferroelectric liquid crystal. The ferroelectric liquid crystal shows a Chevron layer structure. The pretilt angle  alpha of the liquid crystal to the orientation film is in the range 12 DEG -30 DEG , whereby a stable C1U orientation state is obtained at 90% density or more.
Patent DE-69200359-T2 (DE)
Inventor: MATTIUZZO MARIO
IPC: A43B5/04
Filed: 1992-02-21
Granted: 1994-12-22
Abstract: Plastic ski boot comprising: 
 
  - a shell (1) intended to receive the skier's foot and lower leg; 
  - a deformable shaft (collar) (3) articulated (4) relative to the shell (1), intended to enclose the lower leg and having a wide opening (15) in its rear part and, on the front of the flaps (7, 8), overlapping and interacting with members for closure (38, 37) and for gripping; 
  - a rigid rear cover piece (20) articulated relative to the shell (1) and intended to close off the rear opening of the deformable shaft (collar) (3); 
  - an inner (bootee) (40) intended to receive the skier's foot and lower leg, 
 characterised in that, in the use position, the rear cover piece (20) bears by abutting on the shaft (collar) (3) and is held up against the shaft (collar) (3) by a closure member (30, 31). 
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Patent DE-69208948-T2 (DE)
Inventor: PENMAN DAVID GERARD DR
IPC: G01N27/333
Filed: 1992-01-09
Granted: 1996-09-12
Abstract: PCT No. PCT/GB92/00049 Sec. 371 Date Oct. 13, 1992 Sec. 102(e) Date Oct. 13, 1992 PCT Filed Jan. 2, 1992 PCT Pub. No. WO91/18549 PCT Pub. Date Dec. 12, 1991.A pH electrode suitable for in vivo use is provided in a cannula 10, and comprises a reference electrode 14 consisting of a chloridized silver wire surrounded by a solid unbuffered internal reference material 16 comprising potassium chloride, silver chloride, citric acid and sorbitol as a hygroscopic agent. The material 16 is surrounded by a PVC sleeve 12. The tip of the cannula 10 has a pH sensitive polymer-based membrane 20 across its end. The reference material has a pH when hydrated of about 2 which is below the range of pH response of the membrane 20.
Patent DE-69210937-T2 (DE)
Inventor: ERICSON STEVE
IPC: F04D29/26
Filed: 1992-09-09
Granted: 1996-10-02
Abstract: A centrifugal pump having an impeller (38) which is associated with a motor and a drive shaft (16,14) and that is enclosed within a housing (28). The housing (28) is mounted in surrounding, spaced and non-contacting relationship, with respect to the impeller (38) and drive shaft (14) contains fluid inlet (26,26') through which fluids are directed by the impeller (28) to an outlet from the housing (28). Also provided is a pump which operates from remote locations.
Patent DE-69214513-T2 (DE)
Inventor: TSUSHIMA KENICHI
IPC: B41F27/12
Filed: 1992-05-28
Granted: 1997-05-15
Abstract: An apparatus for mounting a plate (81) on a plate cylinder (21) includes a pair of right and left support levers (68), a pair of right and left arms (72), a plate press roller (73), a plate press pad (70), and a spring member (80). The pair of support levers are supported on a support shaft (66) and driven to swing the support shaft. The support shaft is provided close to a circumferential surface of the plate cylinder to extend parallel with the axial direction thereof. The pair of arms are pivotally supported on the support shaft to be close to the pair of support levers. The plate press roller has two ends pivotally supported on the pair of arms and urges the plate against the circumferential surface of the plate cylinder when the plate is to be wound on the plate cylinder. The plate press pad is fixed on a holding member (69) to couple free end portions of the pair of support levers, and has an elastic surface for pressing a trailing-side of the plate. The spring member is interposed between the free end portion of at least one of the support levers and a free end portion of at least one of the pair of arms. <IMAGE>
Patent DE-69217583-T2 (DE)
Inventor: VINEL PAUL
IPC: H04L12/54
Filed: 1992-06-17
Granted: 1997-06-05
Abstract: According to the invention, the apparatus is of the type comprising a memory in which each virtual channel is assigned a context containing a data set defining the conditions for the evaluation of the data rate of this virtual channel and containing information resulting from earlier steps of this evaluation, a clock contrived to provide a current time and means of processing such that, on reception of each cell, the context of the virtual channel to which this cell belongs is read, this context serving as basis for the evaluation of the data rate, the said apparatus comprising means for proceeding to a cyclic exploration of the said contexts and, during this cyclic exploration, proceeding, for each context, to the incrementation of the contents of a counter of exploration cycles having an initial position, the said apparatus including means (SU) for identifying the virtual channels guaranteeing a minimum data rate and processing means (TR) comparing, for each virtual channel identified, the contents (LS) of the said counter of exploration cycles corresponding to the said identified virtual channel with a predetermined threshold value (S) in order to provide a signal (AL) for detecting cutoff of communication when the contents (LS) of the said counter reach the said predetermined threshold value (S). <IMAGE>
Patent DE-69221198-T2 (DE)
Inventor: RUGER WILLIAM B
IPC: F41A3/14
Filed: 1992-04-23
Granted: 1998-01-02
Abstract: Reinforcement elements are attached to the exterior surface of the slide of an automatic weapon to prevent cracking of the slide at its most vunerable locations.
Patent DE-69225778-T2 (DE)
Inventor: KOIDE KUNIHIRO
IPC: G01N27/30
Filed: 1992-11-26
Granted: 1998-11-19
Abstract: On the inner surface of sensor element (1) made of proton conductive solid electrolyte with perovskite structure and enclosed at its lower end, a reference electrode (2) constituted of porous electrode is formed, and a measuring electrode (3) constituted of porous electrode is formed on the outer surface thereof. And, the reference electrode and the measuring electrode are gas-tightly separated by sealing material. The sensor prove is inserted into ceramic sensor holding cup (10) and both are fixed in such a way that a part of the measuring electrode (3) extrude into said holding cup. Then, by dipping the holder into molten metal (19)by facing its opening part downwards, a space contacting with molten metal is enclosed in the holding cup. Thereby, reduction of solid electrolyte constituting the sensor element can be prevented, and hydrogen concentration in molten metal can be accurately measured without direct dipping the sensor element into molten metal. Thereby, it is possible to provide a sensor probe and a method for measuring hydrogen concentration in which hydrogen concentration can be continuously measured for long period and an apparatus with smaller size can be made. <IMAGE>
Patent DE-69227503-T2 (DE)
Inventor: MARUYAMA MASAO ITAMI WORKS OF
IPC: C22C29/08
Filed: 1992-08-27
Granted: 1999-04-22
Abstract: A hard alloy which is excellent in the machining characteristics as a tool and has high hardness, abrasion resistance, corrosion resistance and stiffness. The alloy comprises at least 80 wt. % of WC with a mean grain diameter of 2  mu m or less, 0.2-2 wt. % of Co, and the balance comprising at least one member selected among metals, carbides, nitrides and carbonitrides of the group IVa, Va and VIa elements of the periodic table, wherein said at least one member comprises at least one of Mo and Mo2C in an amount of 2.0-7.0 wt. % based on the alloy and COxWyCz is present in the sinter of the alloy. The addition of Mo or Mo2C and VC serves to inhibit the grain growth in the hard phase and improve the wettability of WC-Co. As a result, this alloy is excellent in the machining characteristics as the alloy for tools such as cutting, sliding and wire drawing dies and as a high- pressure water jet nozzle and has high hardness, abrasion resistance, corrosion resistance and stiffness.
Patent DE-69300491-T2 (DE)
Inventor: COCIANCICH ERMANNO
IPC: C07D305/14
Filed: 1993-01-27
Granted: 1996-03-07
Abstract: Processes for the extraction of taxol and derivatives thereof from roots of plants of the genus Taxus are described.
Patent DE-69305033-T2 (DE)
Inventor: HUSSEIN FATHI DAVID
IPC: C08F2/34
Filed: 1993-07-29
Granted: 1997-02-06
Abstract: An improvement in the process for producing sticky polymers in a fluidized bed reactor catalyzed by a transition metal catalyst in the presence of an inert particulate material prone to generate excessive negative charges in said reactor, by conducting the process in the presence of a composition comprising a mixture of an alcohol phosphate salt and a quarternary ammonium salt, which is dissolved in a suitable solvent.
Patent DE-69316998-T2 (DE)
Inventor: MOSS DENNIS
IPC: F02D41/14
Filed: 1993-12-17
Granted: 1998-10-01
Abstract: Oxygen sensor deterioration is detected by initially counting the number of fuel units required to change the output voltage of a nondeteriorated sensor between first and second voltages, and subsequently counting the number of fuel units required to change the output voltage of the sensor between the first and second voltages, as the sensor ages, until a subsequent count exceeds the initial count by a given amount. The method detects when the air/fuel ratio desired for normal engine operation drifts outside acceptable tolerance. The method detects and stores a first difference between air/fuel ratios, corresponding to first and second sensor output voltages, and then subsequently detects a second difference between air/fuel ratios, corresponding respectively to the first and second sensor output voltages. When the second difference exceeds the first difference by a given amount, deterioration is indicated.
Patent DE-69321725-T2 (DE)
Inventor: TANSKANEN JUHA
IPC: C03C25/10
Filed: 1993-05-10
Granted: 1999-05-06
Abstract: PCT No. PCT/FI93/00201 Sec. 371 Date Jan. 3, 1995 Sec. 102(e) Date Jan. 3, 1995 PCT Filed May 10, 1993 PCT Pub. No. WO93/25925 PCT Pub. Date Dec. 23, 1993.The invention relates to a method and an arrangement for coloring optical fibres, each fibre being drawn through an upper nozzle in a coloring tool into a color chamber, into which colorant is introduced, and further through a lower nozzle out of the color chamber. The colored fibre is passed onward through a quartz tube of a UV lamp curing the colorant. To reduce costs and to increase the production rate, the coloring tools are arranged close to each other in pairs in at least two different planes, and the fibres to be colored are drawn simultaneously through the coloring tools and further simultaneously through the quartz tube of the UV lamp common to the fibres to be colored.
Patent DE-69324337-T2 (DE)
Inventor: BLEAKLEY IAN STUART
IPC: C09C1/00
Filed: 1993-12-14
Granted: 2005-01-05
Abstract: There is disclosed a process comprising:     (a) providing an aqueous suspension of particulate kaolin clay; (b) introducing into the aqueous suspension a reagent comprising a source of alkaline earth metal ions and a reagent comprising a source of carbonate ions to precipitate an alkaline earth metal carbonate in the said aqueous suspension of the said particulate kaolin clay whereby the said particulate kaolin clay present at the start of the process becomes entrained in the alkaline earth metal carbonate to form a mixed aggregated material.
Patent DE-69328679-T2 (DE)
Inventor: CHRISTIE JULIE ANN
IPC: C11D3/33
Filed: 1993-07-16
Granted: 2001-01-11
Abstract: The present invention relates to a machine dishwashing composition comprising     from 1% to 80% by weight of detergent builder compound   oxygen-releasing bleaching agent from 0.05% to 2.5% by weight, preferably 0.1% to 1% by weight of paraffin oil,   nitrogen-containing corrosion inhibitor compound Most preferably the oxygen-releasing bleaching agent is incorporated such that the level of available oxygen measured according to the method herein is from 0.3 to 1.7, preferably 0.5 to 1.2
Patent DE-69330218-T2 (DE)
Inventor: FUJII TOSHIO
IPC: C12R1/865
Filed: 1993-06-18
Granted: 2001-10-11
Abstract: This invention disclosed herein provides an alcohol acetyl transferase ("AATase"), an AATase encoding gene and a yeast having an improved ester producing ability due to transformation with the AATase encoding gene. This invention also provides a process for producing an alcoholic beverage having an enriched ester flavor using the transformed yeast.
Patent DE-69332005-T2 (DE)
Inventor: HUGHES PHILIP FLOYD
IPC: A61K31/4353
Filed: 1993-01-14
Granted: 2002-11-14
Abstract: The invention concerns a derivative of rapamycin of general formula   <CHEM> and functional derivatives thereof which by virtue of immunosuppressive activity are useful in treating transplantation rejection host vs. graft disease, autoimmune diseases, and diseases of inflammation.
Patent DE-69401218-T2 (DE)
Inventor: FAUCONET MICHEL
IPC: C07C67/58
Filed: 1994-01-24
Granted: 1997-07-03
Abstract: An alkyl (meth)acrylate is prepared by a direct esterification (in 1) of (meth)acrylic acid by the corresponding alcohol, catalysed by H2SO4. The crude reaction mixture (B1), comprising the targeted ester, alcohol, (meth)acrylic acid, alkyl acid sulphate (alkyl hydrogen sulphate) and traces of H2SO4, is treated (in 3) with a base in order to neutralise the acid species, the resulting salts passing into the aqueous phase (A1), which is separated from the organic phase (O1) containing the targeted ester. The light products (L1), containing the alcohol, are recovered (in 4) from the aqueous phase and the waste water (E2) is discarded. The alkyl acid sulphate present in the aqueous phase (A1) resulting from the separation carried out after the neutralisation (in 3) is hydrolysed (in 8) to form, in this phase, alcohol and H2SO4, the acid species resulting from the hydrolysis are neutralised by introduction into the medium of a base and the resulting aqueous phase (A3) is sent to the alcohol recovery stage. Pollution of the waste water (E2), attributable to the alkyl acid sulphate, is thus avoided. <IMAGE>
Patent DE-69401346-T2 (DE)
Inventor: MIRET EMILI
IPC: B65D71/00
Filed: 1994-04-05
Granted: 1997-04-30
Abstract: PCT No. PCT/GB94/00725 Sec. 371 Date Nov. 1, 1995 Sec. 102(e) Date Nov. 1, 1995 PCT Filed Apr. 5, 1994 PCT Pub. No. WO94/22737 PCT Pub. Date Oct. 13, 1994A paperboard sleeve (10) for wrapping a plurality of brick-shaped containers (11) is disclosed. The sleeve has two opposed and interlocking base panels (21, 22) with flaps (32) formed as a part thereof, the flaps being sized and shaped to be folded back against protruding base tucks (13) formed on the bases of the containers. The engagement of the flaps against the base tucks on the bottom of the containers prevents the movement of the containers through the open ends of the paperboard sleeve after it is formed about the containers.