baber/WOPTO huggingface dataset:
Patent EP-3934663-A1 (EP)
Inventor: WOELFLE-GUPTA CAROLINE
IPC: A61K31/77
Filed: 2020-02-26
Abstract: Embodiments are directed towards methods of inducing caspase activity. The methods include contacting a cell with a treatment compound represented by the following Formula (I): where R 1  is selected from hydrogen or an alkyl group having from 1 to about 16 carbon atoms; R 2  is selected from a hydroxyl group, a tosylate group, an alkoxy group of the formula OR 3  where R 3  is selected from an alkyl group having from 1 to about 16 carbon atoms, or an ester group of the formula OCOR 4 , where R 4  is an alkyl group having from 1 to about 16 carbon atoms, and n is from 4 to 46,000, with the proviso that when R 1  is hydrogen and R 2  is a hydroxy group the treatment compound has a number average molecular weight from 10,100 to 2,000,0000 g/mol.
Patent EP-3953302-A1 (EP)
Inventor: RUIZ-GONZALEZ FRANCISCO-MANUEL
IPC: C01B33/158
Filed: 2020-04-09
Abstract: The application describes a process for producing a simple and inexpensive hydrophobic silica aerogel using a sodium silicate solution as a silica precursor.
Patent EP-3702516-A1 (EP)
Inventor: HUANG TAO
IPC: D06F39/02
Filed: 2020-01-16
Abstract: The disclosure relates to the technical field of washing machines and in particular relates to an additive auto-feeding device, including a water supply flow channel; a liquid storage box containing an additive inside; a suction structure capable of sucking the additive in the liquid storage box to the water supply flow channel and then transferring the additive along with water flow to a water outlet; and an anti-back suction device arranged at a pressure adjusting opening of the water supply flow channel, wherein when water enters the water supply flow channel, under the pressure effect of flowing water, the anti-back suction device is controlled to close the pressure adjusting opening; and when negative pressure is generated in the water supply flow channel, the anti-back suction device is controlled to open the pressure adjusting opening for adjusting the pressure in the water supply flow channel. A pressure adjusting device for automatically adjusting opening and closing of an air hole along with the pressure in a tube is arranged in a washing additive auto-feeding device provided in the disclosure, so as to correspondingly adjust the pressure in the tube and avoid existence of negative pressure in the tube, thus achieving the purpose of a backflow prevention function.
Patent EP-3969901-A1 (EP)
Inventor: HANSEN THOMAS STEEN
IPC: G01N33/49
Filed: 2020-05-14
Abstract: La présente invention concerne des procédés de détermination d'un paramètre de gaz sanguin et/ou d'un paramètre de panel métabolique de base dans un échantillon de sang comprenant la combinaison de l'échantillon de sang avec un anticoagulant et un agent antiplaquettaire, et la détermination dudit paramètre de gaz sanguin et/ou paramètre dans l'échantillon. Selon certains aspects, l'invention concerne la détermination desdits paramètres dans des échantillons qui ont été soumis à une contrainte pré-analytique.
Patent EP-4130560-A1 (EP)
Inventor: MARTINEZ WEBER FEDERICO
IPC: F21S8/06
Filed: 2020-04-02
Abstract: The present invention relates to an optical device that enables the projection of the light to be controlled such that it comes out parallel to a non-active multi-cell screening device, wherein said screening device is not illuminated by the light beam, the user perceiving the light with all its intensity, without loss of intensity due to the reflection of said screening device, wherein furthermore, due to the low profile thereof, the optical device enables same to be integrated into a luminaire with a reduced height dimension, which is also object of the present invention.
Patent EP-3976749-A1 (EP)
Inventor: BENSON HANNAH
IPC: C11D11/04
Filed: 2020-05-26
Abstract: A detergent composition for machine dishwashing comprising Z1) one or more ethoxylated glycerol esters of formula (I), prepared from ethylene oxide and one or more triglycerides of formula (II) in the presence of a calcium catalyst (C), characterized in that R1, R2 and R3 in formulae (I) and (II) are equal or different and are independently selected from saturated or unsaturated, linear or branched C7-C24 alkyl chains; m, n and o in formula (I) are equal or different and are each independently an integer number from 1 to 200 with the proviso that the number-average of the sum of m + n + o is greater than 5; and the calcium catalyst (C) is a catalyst obtainable by a reaction involving (A) calcium hydroxide and (B) a carboxylic acid comprising 3 to 40 carbon atoms, wherein the molar ratio of calcium hydroxide (A) to carboxylic acid (B) in the preparation of the catalyst (C) is from 1:1 to 1:5.
Patent EP-3983562-A1 (EP)
Inventor: LAMBRECHTS DIETHER
IPC: C12Q1/6883
Filed: 2020-06-17
Abstract: The present invention relates to biomarkers for predicting the risk of developing chronic allograft injury in a patient, and means and methods for (post-transplant) preservation of allografts and transplantation organs. In particular, a method to predict the risk of developing chronic allograft injury in a patient is presented based on age-related increase of methylation of CpGs. In particular, the allograft is a kidney.
Patent EP-3983742-A1 (EP)
Inventor: THOMSEN PETER
IPC: F28D1/02
Filed: 2020-06-15
Abstract: A heat exchanger (10) is disclosed for providing heat exchange between fluids (24, 25), comprising a pipe bundle (17) extending between first and second pipe connectors (13, 14) and configured to guide a second fluid (25) between the first and second pipe connectors (13, 14), the pipes (17a-17n) being distributed in layers (22) of pipes (17a-17n), wherein a plurality of pipes (17a-17n) of each of said layers (22) of pipes each comprises two bends (B1, B2), so that the respective pipe provides three substantially parallel flow path sections (S1, S2, S3), wherein the length (L1) of a longer (S1) of said flow path sections of the respective pipe is at least 1.7 times greater than the length (L2) of the other two shorter flow path sections (S2, S3) of said pipe, wherein a first (B1) of said bends (B1, B2) is provided between the longer flow path section (S1) and a first of said shorter flow path section (S2), and wherein the other (B2) of said bends is provided between said first, shorter flow path section (S2) and the other shorter flow path section (S3), wherein each of said layers of pipes (17a-17n) comprises two pipe subgroups (SG1, SG2), wherein the longer (S1) of said flow path sections of one of said subgroups (SG1, SG2) is connected to a first of said pipe connectors (13, 14), and wherein the longer (S1) of said flow path sections of the other of said subgroups (SG1, SG2) is connected to the other of said pipe connectors (13, 14), and wherein the bend (B2) between the two shorter flow path sections (S2, S3) of the respective pipes in one of said pipe subgroups (SG1) in the pipe layer (22) is arranged substantially opposite to bends (B2) extending between the two shorter flow path sections (S2, S3) of pipes in the other pipe subgroup (SG2) of the same pipe layer (22).
Patent EP-3912868-A1 (EP)
Inventor: Kazakov Korshunova
IPC: B60R22/347
Filed: 2020-01-17
Abstract: The invention relates to a supporting and securing device (1) that is fixed to a scooter-like vehicle (12) or similar by means of a gripping mechanism (5) to secure and grip a user (13) of the vehicle (12). The device (1) comprises a mechanism (6) configured to roll up and lock a belt (7) that surrounds the user (13), securing and supporting him or her and surrounding a part of his or her back. The mechanism (6) automatically adjusts to the user's position and comprises a pressing assembly (2) that allows the length of the unwound belt (7) to be fixed, and a coupling element (8) that connects to a main case (11). The invention also relates to the vehicle (12) comprising the described device (1). The invention falls within the technical field of parts of vehicles (1), more specifically vehicle safety belts or harnesses or ease of use while driving.
Patent EP-3913088-A1 (EP)
Inventor: ARAI SATOSHI
IPC: C21D8/12
Filed: 2020-01-16
Abstract: The method for manufacturing a grain-oriented electrical steel sheet is a method for manufacturing a grain-oriented electrical steel sheet including a strain region forming process of irradiating the grain-oriented electrical steel sheet having a base steel sheet (1), an intermediate layer (4) disposed to be in contact with the base steel sheet (1), and an insulation coating (3) disposed to be in contact with the intermediate layer (4) with an electron beam and forming a strain region (D) which extends in a direction intersecting a rolling direction of the base steel sheet (1) on a surface of the base steel sheet (1), wherein, in the strain region forming process, a temperature of a central portion of the strain region (D) in the rolling direction of the base steel sheet (1) and an extension direction of the strain region (D) is heated to 800°C or higher and 2000°C or lower.
Patent EP-3996836-A1 (EP)
Inventor: EVANS MARTIN
IPC: B01J8/00
Filed: 2020-07-08
Abstract: An addition system for introducing particulate material into an industrial process is disclosed. The addition system comprises a vessel for holding the particulate material, wherein the vessel has a top and a bottom; one or more weighing devices; a controller for controlling operation of the addition system; a base plate to support the vessel and optionally the controller; and three or more legs, each leg having an uppermost section that connects to the vessel and a foot that is connected to the base plate. The widest diameter of the vessel is less than the diameter of a circle drawn through the feet of the legs. The one or more weighing device are mounted on the base plate and support the legs of the vessel.
Patent EP-3921048-A1 (EP)
Inventor: WANG CALVIN S
IPC: A63B53/04
Filed: 2020-02-06
Abstract: Embodiments of golf club heads with energy storage characteristics are presented herein. In some embodiments, a golf club head comprises a hollow body comprising a strikeface, a heel region, a toe region opposite the heel region, a sole, a top rail and an inflection point. The inflection point provides increase bending of the strikeface thereby providing performance enhancement over clubs without an inflection point.
Patent EP-3880422-A1 (EP)
Inventor: HECK ANDREAS
IPC: F16B25/00
Filed: 2020-07-31
Abstract: Gezeigt wird ein System zum Befestigen eines Ankers (40) in einem Bohrloch in einem mineralischen Untergrund, insbesondere Beton, Mörtel oder Mauerwerk, umfassend einen Anker (40) mit einem Kernabschnitt und einem Gewindeabschnitt (51), und ein Furchwerkzeug (10) zum Furchen eines Innengewindes in dem Bohrloch, wobei das Furchwerkzeug (10) folgendes umfasst: einen Grundkörper (12) mit einem führenden und einem nachlaufenden Ende (12a, 12b), wobei ein Kraftangriff vorgesehen ist, über den ein Drehmoment zum Eindrehen des Furchwerkzeugs (10) in das Bohrloch und zum Furchen des Gewindes auf den Grundkörper (12) übertragbar ist, wobei der Grundkörper (12) eine Außenfläche hat, auf der ein Furchgewinde (18) ausgebildet ist, welches geeignet ist, das Innengewinde in die Wand des Bohrlochs zu furchen. Das Furchwerkzeug (10) weist an seinem führenden Ende (12a) ein Antriebselement (34) auf, welches geeignet ist, mit einem Kraftangriff des Ankers (40) oder eines Teils desselben zusammenzuwirken, der in das mit dem Furchwerkzeug behandelte Bohrloch einzuschrauben ist.
Patent EP-3741173-A1 (EP)
Title: Tsn support
Inventor: MARCO OLIVIER
IPC: H04W72/04
Filed: 2020-02-12
Abstract: Processes and systems for managing preconfigured resources, in particular wireless transmission resources. The disclosure particularly addresses the management of preconfigured resources in relation to Time Sensitive Network (TSN) data transmission. In addition to allocating periodic preconfigured resources, an allowed transmission window (ATW) is defined. The ATW defines which occurrences of the preconfigured resources may be utilised for transmission, in particular which uplink transmission resources may be utilised by a UE. The ATW may be aligned with the expected time of arrival of TSN data (typically the ingress time window) such that the TSN data can be promptly transmitted. The occurrences which occur outside of the ATW are not to be used for transmission and hence may be re-allocated by the base station for other uses.
Patent EP-3938788-A1 (EP)
Inventor: KIM SEONG JIN
IPC: G01N33/574
Filed: 2020-02-12
Abstract: The present application discloses a composition for use in diagnosing cancer, the composition comprising: an antibody or antigen-binding fragment thereof that specifically binds to a BAG2 polypeptide or fragment thereof.
Patent EP-4007752-A1 (EP)
Inventor: TAMAYO NURIA A
IPC: C07D413/12
Filed: 2020-08-03
Abstract: L'invention concerne des composés amide de formule (I) : et des compositions les contenant, et des procédés de préparation de tels composés. L'invention concerne également des procédés de traitement de troubles ou de maladies pouvant être traités par inhibition de la protéine du moteur de la kinésine KIF18A, tels que le cancer, le psoriasis, la dermatite atopique, un trouble auto-immun, ou une maladie intestinale inflammatoire, et analogues.
Patent EP-4007760-A1 (EP)
Inventor: PASCHALIDES NICHOLAS
IPC: A61P35/00
Filed: 2020-07-31
Abstract: The present invention is directed to a solid-state DMF solvate of relugolix and to solid-state anhydrous forms of relugolix designated as Form A and Form C of anhydrous relugolix. The present invention is further directed to processes for the preparation of the solid-state DMF solvate of relugolix and each of Form A, Form B, and Form C of anhydrous relugolix. The present invention also is directed to pharmaceutical compositions comprising the DMF solvate of relugolix or Form A or Form C of anhydrous relugolix, and to a method for treating disease using the DMF solvate of relugolix or Form A or Form C of anhydrous relugolix.
Patent EP-3930054-A1 (EP)
Inventor: TANG WEICHAO
IPC: C08F212/08
Filed: 2020-02-11
Abstract: A cross-linked SBR microsphere binder and a preparation method, and a lithium-ion battery containing the binder, the cross-linked SBR microsphere binder has a porous cross-linked structure, the cross-linked SBR microsphere has a particle size of 10 nm - 1 µm, and a porosity of 0.01% - 40%, and a pore diameter of the pore is greater than 0 and less than or equal to 200 nm. The lithium-ion battery containing the binder has advantages of better rate performance, low temperature performance, fast charge performance, and long cycle performance, compared with a lithium-ion battery containing a conventional SBR binder.
Patent EP-3929276-A1 (EP)
Inventor: MIYAUCHI YUKI
IPC: C12M1/34
Filed: 2020-02-03
Abstract: When the target (30) is not supplied, the binding via the binding part is maintained, and when the donor fluorescent molecule (11) is excited, energy is transferred to the acceptor fluorescent molecule (21) that is close to the donor fluorescent molecule (11). Then, the acceptor fluorescent molecule (21) exhibits fluorescence. When the target (30) is supplied, the target (30) is bound to the detection part to release the binding via the binding part, and the acceptor fluorescent molecule (21) is separated from the donor fluorescent molecule (11). Then, the donor fluorescent molecule (11) exhibits fluorescence.
Patent EP-3940240-A1 (EP)
Inventor: ENOSAWA HIDEKI
IPC: F04D19/04
Filed: 2020-03-09
Abstract: A thickness of deposited material just before a cause of a disruption to operation of a vacuum pump occurs is detected at a flow path position where the cause is to occur. A deposited material sensor is arranged, in a flow path of a gas from an inlet port to an outlet port, on an upstream side or a downstream side of a predetermined flow path position where a cause of disruption to operation of the vacuum pump is to occur. In addition, the deposited material sensor detects a presence or absence of deposited material at the arrangement position of the deposited material sensor, and the arrangement position of the deposited material sensor is a position where a thickness of the deposited material at the predetermined flow path position assumes a predetermined thickness that corresponds to a maintenance time of maintenance for suppressing the cause when a detection state of the deposited material sensor changes from deposited material absent to deposited material present.
Patent EP-3937982-A1 (EP)
Inventor: PANICKER RAJESH KRISHNAN GOPALAKRISHNA
IPC: A61K38/20
Filed: 2020-03-13
Abstract: The present disclosure relates to methods and compositions comprising derivatized-chitosan polyplexes reversibly coated with a polyanion-containing block co-polymer for the localized expression of IL-12 in mucosal tissues, preferably in combination with an IFN- 1 activator/inducer, for use in cancer immunotherapy.
Patent EP-3942342-A1 (EP)
Inventor: ISLAM NAHID
IPC: G02B6/38
Filed: 2020-03-13
Abstract: The present disclosure describes fusion spliced cable assemblies. An assembly may include a first and a second fiber optic cable, where an end of at least a first optical fiber from the first fiber optic cable is fusion spliced together with an end of at least a second optical fiber from the second fiber optic cable, the first optical fiber having a first length of prepared fiber extending from the spliced end of the first optical fiber to a transition point of the first optical fiber, the second optical fiber having a second length of prepared fiber extending from the spliced end of the second optical fiber to a transition point of the second optical fiber, where the transition point of the first optical fiber is a distance from the transition point of the second optical fiber, and where a total length of prepared fiber is the sum of the first length of prepared fiber for the first optical fiber and the second length of prepared fiber for the second optical fiber; a support configured to engage at least a portion of the total length of prepared fiber such that the distance between the transition points of each optical fiber is less than the total length of prepared fiber of the first and second optical fibers; and a transition housing coupled to the first and second fiber optic cables and surrounding the support. Fusion spliced cable assembly breakout kits are also provided.
Patent EP-4027823-A1 (EP)
Inventor: TAYLOR BRANT MICHAEL
IPC: A41D13/08
Filed: 2020-09-11
Abstract: A protective padding section includes an upper layer (36), an opposing lower layer (38) and a repeating array of cushioning regions (22) disposed between, and continuously bonded to, the upper layer and the lower layer. Each cushioning region has a same first cushion thickness. A repeating array of apertures (28) is disposed between the cushioning regions and each aperture extends through the padding section. The padding section has a first thickness and a first width and upon application of a force, the padding section expands in width from the first width to a second width greater than the first width and when the application of force is removed, the width of the padding section contracts to the first width.
Patent EP-4010878-A1 (EP)
Inventor: KHANSARI ZADEH SEYED MOHAMMAD
IPC: G06T7/73
Filed: 2020-09-15
Abstract: Generating and utilizing action image(s) that represent a candidate pose ( e.g. , a candidate end effector pose), in determining whether to utilize the candidate pose in performance of a robotic task. The action image(s) and corresponding current image(s) can be processed, using a trained critic network, to generate a value that indicates a probability of success of the robotic task if component(s) of the robot are traversed to the particular pose. When the value satisfies one or more conditions  (e.g. , satisfies a threshold), the robot can be controlled to cause the component(s) to traverse to the particular pose in performing the robotic task.
Patent EP-3951028-A1 (EP)
Inventor: TSUGE KENJI
IPC: C40B40/06
Filed: 2020-03-24
Abstract: The present invention addresses the problem of providing a novel method which is for preparing a DNA fragment for microbial cell transformation, and by which the combinatorial library of a long-chain DNA can be efficiently constructed and confirmation of the genotype of the obtained clone is facilitated. The present invention is a method for preparing a DNA fragment, which is for microbial cell transformation and has at least one insert DNA unit that includes a DNA containing an effective replication origin in a host microorganism and an insert DNA in which unit DNAs are linked, the method being characterized by including: (A) a step for preparing, through an OGAB method, a plurality of types of plasmids having an insert DNA unit in which a plurality of types of unit DNAs capable of being linked in a specific linking order are linked; (B) a step for decomposing a plasmid into unit DNAs by treating the plurality of types of plasmids prepared in the step (A) with a restriction enzyme suitable for each plasmid and preparing a mixed liquid of a plurality of types of unit DNAs; and (C) a step for preparing a long-chain DNA fragment by re-assembling the unit DNAs through the OGAB method by using the mixed liquid of a plurality of types of unit DNAs obtained in the step (B) .
Patent EP-4045500-A1 (EP)
Inventor: PLATZEK JOHANNES
IPC: C07B57/00
Filed: 2020-10-12
Abstract: Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von Acyloxymethylestern der (4S) -(4-Cyano- 2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-3-carbonsäure der Formel (IIa) durch Racematspaltung von der Verbindung der Formel (II) unter Verwendung einer Hydrolase. Die Erfindung betrifft auch ein Verfahren zur Herstellung von (4S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro- 1,6-naphthyridin-3-carboxamid der Formel (Ia), wobei das Verfahren die Racematspaltung von der Verbindung der Formel (II) unter Verwendung einer Hydrolase umfasst. Zudem betrifft die Erfindung auch die Verwendung einer Hydrolase in einem Verfahren zur Herstellung einer Verbindung nach Formel (IIa). Die Erfindung betrifft ferner die Verwendung einer Hydrolase in einem Verfahren zur Herstellung einer Verbindung nach Formel (Ia).
Patent EP-4044855-A1 (EP)
Inventor: PRESTIA IVAN
IPC: A24F47/00
Filed: 2020-10-16
Abstract: The present invention relates to a charger for charging an aerosol-generating device. The charger comprises a housing defining a cavity for receiving the aerosol-generating device to be charged. The cavity has an opening. At least one electrical contact is located in the cavity. A cover is slidable relative to the opening between an open position and a closed position. An inner surface of the cover faces the cavity when the cover is in the closed position and at least a portion of the inner surface of the cover defines a profiled engagement member that sloping into, or towards, the cavity when the cover is in the closed position. The cover, in the closed position, ensures that electrical communication is maintained between the charger and an aerosol-generating device received in the charger. The invention further relates to an aerosol-generating system comprising the charger and an aerosol-generating device and a method of using the aerosol-generating system.
Patent EP-4021608-A1 (EP)
Title: Composition for separation of an oil water mixture
Inventor: MARIN ADRIANO
IPC: B01D17/04
Filed: 2020-10-09
Abstract: The present invention relates to a method for the separation of an oily mixture from an aqueous mixture and a kit for use in said method.
Patent EP-3962955-A1 (EP)
Title: Antigen specific cd19-targeted car-t cells
Inventor: AFTAB BLAKE T
IPC: A61P35/02
Filed: 2020-04-29
Abstract: Disclosed are compositions and methods for targeted treatment of cancer, such as hematologic cancer. In particular, chimeric antigen receptor (CAR) T cells are disclosed that can be used with adoptive cell transfer to target and kill cancer cells with reduced antigen escape. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with hematologic cancer that involves adoptive transfer of the disclosed CAR T cells.