baber/WOPTO huggingface dataset:
Patent DE-69404632-D1 (DE)
Inventor: BUTLER Donald
IPC: A61K31/4427
Filed: 1994-02-24
Granted: 1997-09-04
Abstract: An improved process for the preparation of trans-6-(2-(substituted-pyrrole-1-yl)alkyl)pyran-2-ones by a novel synthesis is described where (alpha)-metalated N,N-disubstituted acetamide is converted in seven operations to the desired products, and specifically, a process for preparing (2R-trans)-5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1H-pyrrole-3-carboxamide, as well as other valuable intermediates used in the processes and prodrugs which are bioconverted to hypolipidemic and hypocholesterolemic agents and pharmaceutical compositions of the same.
Patent DE-69408335-D1 (DE)
Inventor: GOEBEL JUNGHANNS CARLO
IPC: B05D7/00
Filed: 1994-10-17
Granted: 1998-03-05
Abstract: The present invention relates to thermosetting powdered paints in various colors that contain bleeding pigments or colors which, when mixed together and subsequently applied with a particular two-coat cycle, allow to obtain uniform tints having a high hiding power that cannot be obtained with the thermosetting powdered paints used so far, which produce the phenomenon known as "salt-and-pepper" effect if their colors are different and they are mixed together.
Patent DE-69424674-D1 (DE)
Inventor: ROGERS D
IPC: H01H67/26
Filed: 1994-08-23
Granted: 2000-06-29
Abstract: A switching matrix includes at least two parallel circuit boards each having plural conductive traces and multiple matrix holes therethrough arranged to permit traces on one board to be connected to traces on the second board. Connection is achieved by means of a flexible non-conductive circuit jumper pin having a resilient conductive sleeve arranged to extend between an aligned pair of holes in the two boards. The holes are conductively plated to define female contacts to radially compress the conductive sleeve. Circuit jumper pins may be moved between different matrix positions manually or by a pick and place mechanism controlled from a remote location. In one embodiment, serving as a telephone cross-connect switch, connections are made in pairs, therebeing four circuit boards and two conductive sleeves on each pin, each sleeve interconnecting a pair of traces on a respective pair of boards. In this embodiment the pins are inserted to the first board and external connections to the matrix are made via plug-end connectors at the fourth board. Connections between the first and fourth boards are provided by jumper rods extending through aligned jumper holes defined in each board. Housekeeping holes are provided at the matrix periphery to jump signals between the first and second boards and between the third and fourth boards.
Patent DE-69425230-D1 (DE)
Inventor: NOMA TAKASHI
IPC: H01J9/02
Filed: 1994-12-16
Granted: 2000-08-17
Abstract: An electron-emitting device comprising a pair of device electrodes and an electroconductive film including an electron-emitting region is manufactured by a method comprising a process of forming an electroconductive film including steps of forming a pattern on a thin film containing a metal element on the basis of a difference of chemical state, and removing part of the thin film on the basis of the difference of chemical state. <IMAGE>
Patent DE-69425371-D1 (DE)
Inventor: BOURZAT JEAN-DOMINIQUE
IPC: C07D417/04
Filed: 1994-04-14
Granted: 2000-08-31
Abstract: A method for preparing 3-hydroxy (3R,4S)-2-azetidinones of general formula (Ia), and the use thereof for preparing taxoids, are disclosed. In general formula (Ia), Ar is an aryl radical.
Patent DE-69428206-D1 (DE)
Inventor: NAKANO JUN
IPC: C07D207/16
Filed: 1994-10-27
Granted: 2001-10-11
Abstract: Quinolinecarboxylic acid derivatives which are represented by the general formula (I) <CHEM> wherein R1 is a C1 to C6 alkyl group which may be substituted, a C2 to C6 alkenyl group which may be substituted, a C3 to C7 cycloalkyl group which may be substituted or an aryl group which may be substituted, R2 is hydrogen atom; a halogen atom; hydroxyl group which may be protected, amino group or a C1 to C6 alkylamino group each of which may be protected; a C1 to C6 dialkylamino group or a C1 to C6 alkyl group,  R3 is hydrogen atom or a C1 to C6 alkyl group,  A is nitrogen atom or <CHEM> wherein A' is hydrogen atom, a halogen atom, a C1 to C6 alkyl group, a C1 to C6 alkoxyl group which may be substituted, cyano group, or nitro group, and A' may form a ring with R1; the ring may include oxygen atom, nitrogen atom, or sulfur atom as a constituent atom; the ring may be substituted with a C1 to C6 alkyl group, X is hydroxymethyl group; aminomethyl group or amino group each of which may be protected, and salts thereof, and antibacterial agents which comprise the quinolinecarboxylic acid derivatives and salts thereof as active ingredients, and therapeutical methods thereby.
Patent DE-69428222-D1 (DE)
Inventor: MACLEAY RONALD E
IPC: C08F212/08
Filed: 1994-01-07
Granted: 2001-10-18
Abstract: Peroxy-terminated poly(epsilon-caprolactones) of formula (A-X)m-R-(X'-B)n (I), are new. A = H-(O-(CH2)5-C(O))y-; B = (i); m = 0-3; n = 1-4; (m+n) = 1-4; R1,R2 = 1-4C alkyl; R3 = 1-12C alkyl or 2-12C acetylenic; y = 0-10000; x = 4-22000; (y)(m)+(x)(n) = 4-22000; X,X' = -O- or -N(R4)-; R = opt. substd. aliphatic, alicyclic, aromatic or araliphatic (di-, tri- or tetra-) radical; when n+m = 1, R = opt. substd. radical selected from 1-20C aliphatic, 5-18C alicyclic, 6-14C aromatic, 7-22C araliphatic and (non)aromatic 5-12C heterocyclic; when n+m = 2, R = opt. substd. diradical selected from 2-20C aliphatic, 4-20C aliphatic interrupted by 1-3 -O-, -S- or -N(R4)- gps. in the chain provided that multiple heteroatoms are sepd. from each other and the diradical chain ends by at least 2C, 5-18C alicyclic, 6-12C aromatic where R is a hydrocarbon with 2 free valencies and an aromatic carbocyclic unit(s), and 7-22C araliphatic; when n+m = 3, R = opt. substd. triradical selected from 3-20C aliphatic, 5-18C alicyclic, 6-14C aromatic and 7-22C araliphatic; when n+m = 4, R = opt. substd. tetraradical selected from 4-20C aliphatic, 6-18C alicyclic, 6-14C aromatic and 7-22C araliphatic; R4 = H or opt. substd. 1-20C aliphatic, 5-18C alicyclic, 6-14C aromatic or 7-22C araliphatic; and substits. for R and R4 = Cl, Br, 1-8C alkyl, 1-12C alkoxy, 6-10C aryloxy and/or cyano, and additional substits. for R = 1-4C acyloxy and/or (meth)acryloyloxy.
Patent DE-69433939-D1 (DE)
Inventor: PRUSS P
IPC: A61F13/00
Filed: 1994-11-03
Granted: 2004-09-16
Abstract: A fibrogen-free substrate having as a hemostatic agent on a surface thereof a mixture of a clot-promoting amount of thrombin and an amount of epsilon aminocaproic acid (EACA) effective to accelerate the rate of blood clotting induced by the thrombin is useful as a hemostatic patch which is safe, inexpensive and which rapidly controls bleeding from a wound. A patch which rapidly stanches the flow of blood from a lesion on a parenchymal organ by pressing it against the surface of the organ for 3-5 minutes, is produced by applying thrombin, EACA and CaCl2 to a rigid sheet of biodegradable foam, such as an absorbable gelatin sponge, and compressing the dry sheet to produce a flexible sheet which conforms to the contour of the organ without the necessity of pre-moistening. The problem associated with thrombin-fibrinogen glues of adhesion of the wounded surface of the organ to adjacent tissue is avoided by applying the hemostatic agent to only the wound-contacting face of the sheet.
Patent DE-69509148-D1 (DE)
Inventor: ANDERSSON INGVAR
IPC: B41F13/20
Filed: 1995-02-06
Granted: 1999-05-27
Abstract: The different cylinders (1,3,6,7) of a printing unit in a rotary printing press are arranged in a vertical row under the impression cylinder (8) of the press and are rotatable in a frame (13) of the printing unit. Each cylinder is at each end rotatably journalled in a bearing housing (30,31), which is displaceable on a vertical bearing rail (39). A hydraulic cylinder (43) is arranged in the frame under the lowermost bearing housing in a stack thereof for lifting the bearing housings into engagement with each other or for lowering them. <IMAGE>
Patent DE-69510510-D1 (DE)
Inventor: FOGUET RAFAEL
IPC: A61P25/26
Filed: 1995-03-17
Granted: 1999-08-05
Abstract: PCT No. PCT/EP95/01007 Sec. 371 Date Feb. 20, 1996 Sec. 102(e) Date Feb. 20, 1996 PCT Filed Mar. 17, 1995 PCT Pub. No. WO95/25732 PCT Pub. Date Sep. 28, 1995The invention relates to new N-benzoylmethyl-piperidines of the general formula (I):    <IMAGE>  (I)  wherein X is a halogen atom, as well as their pharmaceutically acceptable addition salts. The compounds are potentially useful to treat depressions.
Patent DE-69514508-D1 (DE)
Inventor: ROSENGREN FRITZ
IPC: H04N1/00
Filed: 1995-04-10
Granted: 2000-02-17
Abstract: The invention relates to a method and arrangement for deriving an ancillary signal from a compressed digital video signal (e.g. MPEG). The DC coefficients of autonomously encoded pictures (I-pictures) are selected from the compressed signal. The ancillary signal thus obtained can be used for display in a (multi-) picture-in-picture television receiver. A decoder for decoding such an ancillary signal is considerably simpler and less expensive than a full-spec MPEG decoder.
Patent DE-69517050-D1 (DE)
Inventor: GRINDA JEAN-ROBERT
IPC: C07C69/587
Filed: 1995-07-17
Granted: 2000-06-21
Abstract: PCT No. PCT/FR95/00949 Sec. 371 Date Mar. 11, 1997 Sec. 102(e) Date Mar. 11, 1997 PCT Filed Jul. 17, 1995 PCT Pub. No. WO96/02488 PCT Pub. Date Feb. 1, 1996A process for the stabilization of polyunsaturated fatty acids and their alkyl esters wherein the polyunsaturated fatty acids or its alkyl or glyceryl esters is dissolved in an organic solvent and a hydroxy alkyl cellulose or a solution thereof in an inert solvent is added to the resulting solution and the solution is a dispersion evaporated to dryness under a inert gas to form the preparation in powder form which is useful for pharmaceutical formulations or cosmetic formulations.
Patent DE-69525060-D1 (DE)
Inventor: BECK R
IPC: A61K35/54
Filed: 1995-09-08
Granted: 2002-02-21
Abstract: The invention relates to an anti-inflammatory factor isolated from milk, methods of purifying the anti-inflammatory factor resulting in substantially or highly purified preparations and to methods for using this factor to remove adhered neutrophils from endothelial cells, to prevent the emigration of cells from the vasculature and to suppress the response of lymphocytes to foreign antigens.
Patent DE-69529517-D1 (DE)
Inventor: PASTAN IRA
IPC: A61K47/48
Filed: 1995-04-07
Granted: 2003-03-06
Abstract: PCT No. PCT/US95/04468 Sec. 371 Date Jan. 8, 1997 Sec. 102(e) Date Jan. 8, 1997 PCT Filed Apr. 6, 1995 PCT Pub. No. WO95/27732 PCT Pub. Date Oct. 19, 1995The present invention provides for circularly permuted ligands which possess specificity and binding affinity comparable to or greater than the specificity and binding affinity of the original (unpermuted) ligand. The invention further provides for novel chimeric molecules comprising a circularly permuted ligand joined to one or more molecules of interest.
Patent DE-69531408-D1 (DE)
Inventor: ROBERTSON PATRICIA MARY BECKET
IPC: B01L3/00
Filed: 1995-11-06
Granted: 2003-09-04
Abstract: The invention relates to body fluid testing to separate cells or other components of body fluid for appropriate testing or analysis. Hitherto, such as blood testing, has required considerable skill and considerable care in blood sample preparation, and in other areas such as the testing of foetal abnormality has predominately involved invasive techniques, frequently to the discomfort of the mother. The object of the invention is to overcome those disadvantages mentioned above, which objective is met by a means comprising at least one first chamber, a cooperating filter extending across the or each first chamber, at least one second chamber respectively to cooperate with the at least one first chamber, and one or both of said first and second chambers having a connection to vacuum. <IMAGE>
Patent DE-69532113-D1 (DE)
Inventor: DOLLE E
IPC: C07K5/06
Filed: 1995-03-29
Granted: 2003-12-18
Abstract: Disclosed are compounds, compositions and methods for inhibiting interleukin-1 beta  (1L- beta ) protease activity. The compounds, N-(pyrimidinyl)-aspartic acid  alpha -substituted methyl ketones and aspartic acid aldehydes, have the formula (I) set out herein. These compounds are inhibitors of 1 beta -converting enzyme and as such are useful whenever such inhibition is desired. For example, they may be used as research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which IL- beta  protease activity is implicated.
Patent DE-69532682-D1 (DE)
Inventor: KOVAC ZLATA
IPC: H01L21/56
Filed: 1995-09-20
Granted: 2004-04-15
Abstract: A method of making a microelectronic assembly including a compliant interface includes providing a first support structure, such as a flexible dielectric sheet, having a first surface and a porous resilient layer on the first surface of the first support structure, stretching the first support structure and bonding the stretched first support structure to a ring structure. The first surface of a second support structure, such as a semiconductor wafer, is then abutted against the porous layer and, desirably after the abutting step, a first curable liquid is disposed between the first and second support structures and within the porous layer. The first curable liquid may then be at least partially cured.
Patent DE-69603953-D1 (DE)
Inventor: CHARRIN JEAN-JACQUES
IPC: C08F6/00
Filed: 1996-05-06
Granted: 1999-09-30
Abstract: PCT No. PCT/FR96/00686 Sec. 371 Date Nov. 4, 1997 Sec. 102(e) Date Nov. 4, 1997 PCT Filed May 6, 1996 PCT Pub. No. WO94/34897 PCT Pub. Date Nov. 7, 1996A poly(vinyl alcohol) purification process is described, which includes heat treating a poly(vinyl alcohol) under agitation in an atmosphere unsaturated by water and with a water vapor mass content of 20 to 100%. The process of the invention may also include an additional drying step. A poly(vinyl alcohol) with an alcohol content, more particularly a methanol content, of lower than 1% and an ester content, more particularly a methyl acetate content, of lower than 1% is also described, which is provided in the form of flakes a few millimeters in size or of a powder with an average particle size advantageously higher than 600  mu m.
Patent DE-69605058-D1 (DE)
Inventor: WHITEHEAD MATTHEW
IPC: G08B29/18
Filed: 1996-12-20
Granted: 1999-12-09
Abstract: An event detection device comprising a sensing means for generating an output signal in response to the detection of an event, the device comprising a fault monitoring system which comprises: comparator means for comparing the output signal with a threshold signal and for activating a timed sequence processor when the output signal exceeds the threshold signal on a first occasion, the time sequence processor being adapted to activate a fault indicating circuit after a predetermined time interval unless the sensing means generates an output signal in response to the detection of an event on a second occasion within the predetermined time interval.
Patent DE-69606090-D1 (DE)
Inventor: WILLIAMS TERRY MICHAEL
IPC: C02F1/58
Filed: 1996-05-14
Granted: 2000-02-17
Abstract: A method of detoxifying biocide which is toxic to aquatic life comprising contacting said biocide with a water soluble organic thiol compound. Applications of the method are primarily for biocide spills or for industrial effluents which comprise biocide and must be detoxified prior to release into the environment, and must pass a photoluminescent bacterial assay. Kits are also disclosed.
Patent DE-69607108-D1 (DE)
Inventor: JADAUD ALAIN
IPC: H02G3/06
Filed: 1996-11-19
Granted: 2000-04-20
Abstract: The junction (10) between a main conduit (11) and a branch (12) is covered by an accessory (25) with two cheeks (26D,26G) each having frontal and lateral arms (27F,27L) joined at right angles by a beam in the corner (29). Between the cheeks are corresponding closure panels (30F,30L) having a cross-ruled network of lines of least resistance. The network enables the rectangular cut-out (34) to be made as required from e.g. the lateral closure panel (30L) along its free edge (33L) opposite the beam. The frontal arm (27F) of each cheek has a hook at each end for clipping over the body (15) of the main conduit.
Patent DE-69611060-D1 (DE)
Inventor: BRUN CLAUDE
IPC: C08F10/02
Filed: 1996-05-15
Granted: 2001-01-04
Abstract: Process for the formation of particles comprising magnesium chloride, includes contacting solid particles, an organic magnesium deriv., and a chlorinating agent for the magnesium deriv.. Also claimed are: (i) a particle contg. MgCl2; (ii) a cluster of particles contg. MgCl2; (iii) a polyolefin particle; and (iv) a cluster of polyolefin particles.
Patent DE-69619822-D1 (DE)
Inventor: SEINERA HENRI
IPC: C08J11/06
Filed: 1996-06-28
Granted: 2002-04-18
Abstract: A method for processing a substrate, in particular to enable recycling thereof, is disclosed. According to the method, pieces of the substrate are stirred in the presence of an abrasive medium including at least one particulate abrasive agent and at least one liquid. The method may be used for processing waste and/or coated substrates such as polymeric materials from vehicle bumpers and fenders. The resulting products are also disclosed.
Patent DE-69626390-D1 (DE)
Inventor: JONES V
IPC: G08G1/07
Filed: 1996-04-23
Granted: 2003-04-03
Abstract: For qualification for traffic preemption an area is defined and if the vehicle is in the area it can obtain preemption. The vehicle's position is determined, in one embodiment, by use of differential GPS.
Patent DE-69700280-D1 (DE)
Inventor: CANTERI CARLO
IPC: C09K17/22
Filed: 1997-03-18
Granted: 1999-07-22
Abstract: A method for increasing the bearing capacity of foundation soils for buildings consisting in providing a plurality of holes (1) spaced from each other deep in the soil, and in injecting into the soil, through the holes (1), a substance (3) which expands as a consequence of a chemical reaction, with a potential increase in volume of at least five times the volume of the substance before expansion; the expansion of the substance (3) injected into the soil producing compaction of the contiguous soil. <IMAGE>
Patent DE-69700870-D1 (DE)
Inventor: VIVIER DANIEL
IPC: B05B7/00
Filed: 1997-08-28
Granted: 2000-01-05
Abstract: The head, made with a divergent outlet (35) for the foam product, has at least two channels (36) which are fed with the fluid to be converted into foam. The channels are spaced evenly round the circumference of the head, and end at walls (37) lying perpendicular to the direction of ejection, emerging through apertures (38) at the base of the outlet (35) opposite a central boss (39) which is designed to cause the fluid flows to collide. The head is made from a moulded synthetic material with a conical outlet diverging in the direction in which the foam is ejected. It is basically in the shape of a bush with two inner conical ends, and a central section with the channels, walls and central boss which is rounded, especially hemispherical, in shape.
Patent DE-69708870-D1 (DE)
Inventor: SHIMP A
IPC: A61K6/838
Filed: 1997-06-20
Granted: 2002-01-17
Abstract: A process for producing spherical, non-porous hydroxyapatite particles having a size which does not exceed 250 microns and having a density of at least 3.00 g/cc. The process comprises agglomerating in the presence of water as the only additive hydoxyapatite powder feedstock having a purity of at least 97%, and having metallic impurities which do not exceed 500 ppm, to form hydroxyapatite particles having a size which does not exceed 350 microns. The particles are then dried and then sintered at a temperature from about 1,100 DEG  C. to about 1,200 DEG  C. to provide spherical, non-porous hydoxyapatite particles which do not exceed 250 microns and having a density of at least 3.00 g/cc. Such particles have a variety of medical uses, including bone replacement, implant coatings, and dental applications such as alveolar ridge augmentation, root extraction site fillings, restoration of periodontal osseous lesions, and soft tissue augmentations.
Patent DE-69713056-D1 (DE)
Inventor: MCCARTNEY J
IPC: G16H40/20
Filed: 1997-01-15
Granted: 2002-07-11
Abstract: A method and system for evaluating health care provider performance, forecasting health care resource consumption on a macroeconomic scale, and optimizing the allocation of health care resource. The method includes the steps of a) providing patient discharge data which includes an address field indicating one of a plurality of micro-geographical areas (MGAs) wherein a patient resides, b) establishing a referral population for a subject health care provider based upon the market share it has for each cohort in each MGA, c) calculating occurrence rates of medical service demand for the referral population, d) providing and applying population growth factors to the referral population thereby projecting it to a future time, e) applying the occurrence rates to the projected referral population thereby forecasting the consumption of health resources, and f) allocating health care resources in accordance with the forecast. The invention can also factor into the forecast the expected caseload demand from undeveloped or proposed communities. In addition, the invention optionally computes repatriatable caseload volume, i.e. medical service demand which has gone to another health care provider but could be handled by the subject health care provider, and adds this volume to the forecast. Finally, the invention provides for a method for efficiently allocating health resources amongst neighbouring health care providers, based on either current or forecasted medical service demand data.
Patent DE-69716454-D1 (DE)
Inventor: KEINAENEN KARI
IPC: G01N33/542
Filed: 1997-06-30
Granted: 2002-11-21
Abstract: This invention relates to a fluorescence-based immunoassay method for the detection of an analyte, or for the measurement of its concentration in a biological sample. The method is based on the ability of a multivalent analyte to induce aggregation of receptor molecules labeled with a fluorophore, which molecules are anchored to and are freely mobile on a lipid membrane, and thereby cause changes in the fluorescence.
Patent DE-69720146-D1 (DE)
Inventor: REID JOHN S
IPC: C04B35/66
Filed: 1997-12-01
Granted: 2003-04-30
Abstract: Ceramic bodies comprised mainly of zircon and wollastonite, with zircon being the dominant crystalline phase, show improved resistance to alkaline conditions at elevated temperatures than conventional bodies and excellent thermal stability.
Patent DE-69723329-D1 (DE)
Inventor: GORZA ROBERTO
IPC: A43C11/14
Filed: 1997-01-22
Granted: 2003-08-14
Abstract: A fastening device for sports shoes includes a lever arm (2), a traction element (6) articulated to a median portion of the lever arm and having a hook member (10) adapted to engage seats formed on the other flap to be fastened. A spring (11) is arranged in a seat (12) located below the traction member. <IMAGE>
Patent DE-69723473-D1 (DE)
Inventor: MEERS R
IPC: C07K5/08
Filed: 1997-10-15
Granted: 2003-08-14
Abstract: Peptide-lipid conjugates are incorporated into liposomes so as to selectively destabilize the liposomes in the vicinity of target peptidase-secreting cells, and hence, to deliver the liposomes to the vicinity of the target cells, or directly into the cells. The liposomes can thus be used to treat mammals for diseases, disorders or conditions, e.g., tumors, microbial infection and inflammations, characterized by the occurrence of peptidase-secreting cells.