baber/WOPTO huggingface dataset:
Patent CA-2216291-A1 (CA)
Title: Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
Inventor: WOLIN RONALD L
IPC: A61K31/445
Filed: 1996-03-20
Abstract: A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a novel compound of formula (Ia), (Ib) or (Ic) wherein: R and R1 are H, alkyl, halogeno, OH, alkoxy, NH2, alkylamino, dialkylamino, CF3, SO3H, CO2R3, NO2, SO2NH2, or CONHR4; n is 0 or 1; R2 is a group of the formula R5C(O)-, R5CH2C(O)-, R5C(R6)2C(O)-, R5SO2-, R5CH2SO2-, R5SCH2C(O)-, R5OC(O)-, R5NHC(O)-, R5C(O)C(O)-or R5SC(O)-; R5 is alkyl, aryl, arylalkyl, arylalkenyl, heteroaryl, heteroarylalkyl, heteroarylalkenyl or heterocycloalkyl; and R6 is alkyl or C(R6)2 is a carboxyclic ring; or pharmaceutically acceptable salts thereof.
Patent CA-2220208-A1 (CA)
Inventor: TAKENAKA KENJI
IPC: F24J3/00
Filed: 1997-11-05
Abstract: The viscous type heat generator includes a housing having a heating chamber and a heat radiating chamber.  A rotor is rotatably arranged in the heating chamber so that a viscous fluid is subjected to a shearing action to generate heat.  The rotor is fitted on a drive shaft in such a manner that the rotor can not rotate but can move axially relative to the drive shaft.  The front and rear end surfaces of the rotor have wedge effect producing means for correcting an axial offset of the rotor in the heating chamber by the wedge effect caused by the pressure of viscous fluid while the rotor is rotating.  This wedge effect producing means comprises at least three inclined recesses extending in the circumferential direction, the bottoms of which become gradually shallower in the direction opposite to the rotational direction of the rotor.  The inclined recesses are arranged at circumferentially regular intervals and at radially equal positions from the center of the rotor.
Patent CA-2220435-A1 (CA)
Title: Electrolytic pre-enrichment for the combined electrolysis and catalytic exchange process
Inventor: EVERATT ALLAN E
IPC: C01B5/02
Filed: 1996-05-10
Abstract: An electrolytic pre-enrichment of a feed stream to a combined electrolysis and catalytic exchange ("CECE") heavy water production process. A deuterium enriched liquid or vapour stream from electrolytic cells is applied as a feed of the first stage of a CECE deuterium enrichment process. By deploying a portion of available electrolytic cell capacity in the pre-enrichment stage, advantages are achieved, particularly where available electrical power fluctuates or when a "turned down" CECE process is desired.
Patent CA-2221106-A1 (CA)
Title: An interconnection system for viewing and controlling remote server computers
Inventor: HAFER KEVIN J
IPC: H04L29/08
Filed: 1996-08-22
Abstract: A computerized switching system for coupling a workstation to a remotely located computer. A signal conditioning unit receives keyboard and mouse signals generated by a workstation and generates a data packet which is transmitted to a central crosspoint switch. The packet is routed through a crosspoint switch to another signal conditioning unit located at a remotely located computer. The second signal conditioning unit applies the keyboard and mouse commands to the keyboard and mouse connectors of the computer as if the keyboard and mouse were directly coupled to the remote computer. Video signals produced by the remote computer are transmitted through the crosspoint switch to the workstation. Horizontal and vertical sync signals are encoded on to the video signals to reduce the number of cables that extend between the workstation and the remote computer. The signal conditioning units connected to the workstations include an onscreen programming circuit that produces menus for the user on a video display of the workstation.
Patent CA-2223584-A1 (CA)
Title: Crosslinking oligonucleotides
Inventor: TABONE JOHN C
IPC: C12Q1/68
Filed: 1996-06-07
Abstract: Oligonucleotides (ODNs) include a sequence that is complementary to a target sequence in single stranded RNA, or single or double stranded DNA, and an alkylating function which after hybridization alkylates the target sequence.  ODNs adapted for alkylating single stranded RNA, such as messenger RNA, are complementary to the target sequence in the Watson Crick sense. ODNs adapted for alkylating double stranded DNA have at least two alkylating functions and are complementary to the target sequence in the Hoogsteen or reverse Hoogsteen sense. With these ODNs both strands of the target sequence are alkylated. A  third class of ODNs have at least approximately 26 nucleotide units in a continuous sequence which are complementary to the target sequence of double stranded DNA, and the alkylating function is covalently attached to a nucleotide unit in the continuous sequence. Alkylation or cross-linking with this class of ODNs occurs in the presence of a recombinase enzyme.
Patent CA-2225342-A1 (CA)
Inventor: MODAVIS ROBERT A
IPC: C03C25/6208
Filed: 1997-07-29
Abstract: A method for side writing Bragg gratings, having minimal birefringence, in a waveguide structure is disclosed.  The method employs the orientation of the polarization direction of the writing light beam relative to the long axis of the waveguide structure together with the orientation of the intrinsic birefringence slow axis to effectively minimize birefringence in the subject grating.
Patent CA-2227930-A1 (CA)
Title: Sulfonamide-substituted compounds, process for their preparation, their use as a medicament or diagnostic, and a medicament comprising them
Inventor: GERLACH UWE
IPC: A61K31/382
Filed: 1998-01-27
Abstract: Compounds of the formula I (see fig. I) in which R(1) to R(8) and X have the meanings indicated in the claims, are useful for the production of medicaments having K+channel-blocking action; in particular for the production of a medicament for the treatment or prophylaxis of stimulated gastric acid secretion; of ulcers of the stomach and of the intestinal region; of reflux esophagitis; of diarrhea; of all types of arrhythmias, including ventricular and supraventricular arrhythmias; and of reentry arrhythmias and for the prophylaxis of sudden heart death as a result of ventricular fibrillation.
Patent CA-2228991-A1 (CA)
Title: Multi-detector gamma-gamma for measuring formation density
Inventor: WIJEYESEKERA NIHAL I
IPC: G01V5/12
Filed: 1998-02-09
Abstract: The present Invention is an improved method and tool for determining formation density by using an array of gamma-ray detectors. This invention can correct for large standoffs encountered in abnormally shaped boreholes and in particular for the increased standoffs typically encountered by mandrel tools. In this invention the collimated detectors have varying depths of investigation into the formation. At small standoffs a short spaced (SS) detector investigates mainly the mud and mudcake and a shallow layer of the formation. Unlike the SS a mid spaced (MS) detector has a deeper depth of investigation and is sensitive to borehole and formation even at increased standoffs. A long spaced (LS) detector is mainly sensitive to the formation density and its density reading is corrected by using the standoff information from the MS and SS detectors. In addition to measuring density this invention can measure the photo-electric factor (PEF) of the formation. Because photo-electric absorption preferentially removes low energy gamma-rays the tool housing needs to allow passage of low energy gamma-rays. This can be accomplished through the use of a window of a material with a low atomic number (Z) or through the use of a low-Z housing material like titanium. Typical window materials are beryllium and titanium. Housing materials can be titanium or for lower pressure requirements graphite or high-strength carbon compounds.
Patent CA-2231240-A1 (CA)
Inventor: ABRAMS RICHARD S
IPC: A61N1/38
Filed: 1995-10-11
Abstract: An electronic method and apparatus in electroconvulsive therapy (ECT) to automatically measure the electrical dosage of an ECT device at the time of stimulus, and to prevent delivery to the patient of a dosage that is substantially (e.g., more than 5 % or 25 milli-coulomb (mC), or 5 joules (J)) larger than the dosage selected by the operator. When the measured dosage varies more or less than a selected limited amount, or proportion, from the stimulus dial setting (e.g., 5 % or 25 mC or 5J), visible and/or audible signals are triggered and the device is blocked from delivering further stimuli without first being reset. The apparatus includes an output relay driver (17) connected to a high speed controller (27), which is in turn connected to a percent energy selector (23).
Patent CA-2233777-A1 (CA)
Inventor: AMENGUAL GUEDAN JUAN
IPC: H04B14/06
Filed: 1998-04-29
Abstract: Method of adaptive differential pulse code modulation, ADPCM, which fundamentally satisfies the recommendations 6.726 or 6.727 of the CCITT, being implemented in an ADPCM encoder whereby, given an input sample, a quantified difference signal (DQ) is obtained by subtracting from the input sample an estimated value of this sample, the estimated signal (SE), whereby a feedback loop is formed which includes a prediction module (27).   The prediction module (27) calculates, in the preceding frame, the estimated signal (SE) and a partial estimated signal of the sixth order prediction for the current frame sample. Consequently these operations are carried out in parallel with other of the algorithm, resulting in an overall speeding up of the encoding process.
Patent CA-2238246-A1 (CA)
Inventor: YAKO YUKO
IPC: G03F7/039
Filed: 1998-05-21
Abstract: A chemical amplifying type positive photoresist composition, excellent in various properties, and not form necking at the potion where the bottom antireflective coating and the resist film contact, which comprises (A) a resin which is converted to alkali-soluble from alkali-insoluble or alkali slightly soluble by the action of an acid, (B) an acid generator, (C) a tertiary amine compound and (D) a diphenyl sulfone compound, and a fine photoresist pattern can be formed in high precision using the photoresist composition.
Patent CA-2238387-A1 (CA)
Title: Absorbable mixture and coatings for surgical articles fabricated therefrom
Inventor: ROBY MARK S
IPC: A61L17/10
Filed: 1997-06-27
Abstract: Absorbable mixtures are fabricated from a predominant component of fatty acid ester mixed with a copolymer comprising a predominant amount of epsilon-caprolactone and a minor amount of at least one other copolymerizable monomer of other bioabsorbable monomers. These mixtures are useful in forming coating for surgical articles, including multifilament sutures.
Patent CA-2238980-A1 (CA)
Title: Procede permettant d'isoler efficacement des fractions d'espace periplasmique d'echantillons multiples de bacteries
Inventor: GLASER SCOTT M
IPC: C12M1/18
Filed: 1996-11-27
Abstract: L'invention concerne un dispositif à débit élevé permettant d'isoler simultanément des fractions périplasmiques d'échantillons multiples de cellules hôtes. Ce dispositif peut être conçu pour fonctionner en série. Le procédé consiste à utiliser un dispositif à débit élevé destiné à isoler des fractions périplasmiques d'échantillons multiples de cellules hôtes en reliant une chambre d'échantillon à une chambre à vide et à appliquer un vide à ladite chambre, (b) à enlever le milieu avec le vide et (c) à enlever la membrane extérieure des cellules hôtes, (d) à relier une chambre collectrice à la chambre à vide et à appliquer un vide à ladite chambre, de manière à recueillir les fractions périplasmiques des cellules hôtes. L'invention concerne également un poste de travail comprenant un ou plusieurs dispositifs à débit élevé destinés à isoler simultanément des fractions d'espace périplasmiques d'une pluralité d'échantillons de cellules hôtes et elle concerne également ledit dispositif.
Patent CA-2240722-A1 (CA)
Title: Dental care article for pets and process for producing the same
Inventor: KAMEI MASAHARU
IPC: A01K15/02
Filed: 1997-07-29
Abstract: There is provided an edible dental care article, that is so palatable to the taste of pets, clears residual food in the pet's mouth while chewed by a pet, thereby not only preventing adhesion of plaque and formation of dental calculus but giving a massage to the pet's gum. The edible dental care article for pets is characterized in that a casing material is processed in a thread-like manner, a string-like manner, or a thin-tube-like manner; one of the casing material or a combination of the casing material of several kinds, preferably combined with thread-like other proteins, carbohydrates or lipids, is twisted in a string-like manner; cord-like members are tied into a bundle or twisted together so as to make a rope-like member of a prescribed shape in conformity with the kind or size of a pet, with the twists of the rope-like member being treated so as not to loosen.
Patent CA-2241494-A1 (CA)
Title: Universal call access with reverse billing
Inventor: GILBOY CHRISTOPHER P
IPC: H04M15/00
Filed: 1998-06-25
Abstract: A method for billing a telephone call to a called party for a telephone call between a calling party and the called party, comprising the steps of receiving a predetermined access number; prompting for a destination number; determining if the destination number will accept the cost of the telephone call; and completing the telephone call to the destination number. The method may find potential application in a situation where, for example, a child may need to call home from a public telephone, say at a movie theatre or a mall, without using a calling card, credit card, collect charging, an operator, or coins.
Patent CA-2243536-A1 (CA)
Inventor: HASSE MARGARET HENDERSON
IPC: A61F13/15
Filed: 1997-01-16
Abstract: The present invention relates to a sanitary napkin having an adhesive with perfume carrying release agents. Preferably the release agents are microcapsules that release perfume upon removal of a release liner from the adhesive, and/or during the user's wear of the sanitary napkin, and/or upon the removal of the sanitary napkin from the user's undergarment. The perfume releases are either as fragrance bursts, diffusion or both.
Patent CA-2247061-A1 (CA)
Inventor: MIZUGUCHI HIROSHI
IPC: F02B61/04
Filed: 1998-09-11
Abstract: In an outboard marine drive, a tubular socket member is sealingly fitted into an opening formed on one side of the crankcase of the engine at a level corresponding to a normal engine lubricating oil level, and a transparent window member is sealingly fitted into an outer end of the tubular socket member. An engine cover covering the engine is provided with an opening aligned with the transparent window member so as to allow the level of lubricating oil in the crankcase to be inspected from outside the engine cover. The socket member may also be provided with an oil filler pipe bifurcating upwardly from the socket member at an oblique angle, and an oil drain pipe bifurcating downwardly from the socket member at an oblique angle so that filling and removing lubricating o il into and out of the crankcase of the engine can be easily accomplished without complicating the structure for managing engine lubricating oil.
Patent CA-2247063-A1 (CA)
Title: Treatment of macular edema
Inventor: HARRIS ALON
IPC: A61K45/00
Filed: 1997-02-25
Abstract: There is disclosed a method for treating and/or preventing macular edema and age-related macular degeneration which comprises topical administration of carbonic anhydrase inhibitors to the eye.
Patent CA-2247778-A1 (CA)
Title: Liquor oxalate stabilizers
Inventor: FARQUHARSON GRAEME J
IPC: C01F7/145
Filed: 1998-09-25
Abstract: A new and improved method for inhibiting the precipitation of sodium oxalate crystals in a Bayer process liquor is provided. In an embodiment, the method comprises the step of adding to the Bayer process liquor, after red mud separation, a minor effective amount of a liquor oxalate stabilizer selected from hydrocarbon-substituted amine oxide compounds and/or hydrocarbon-substituted betaine compounds.
Patent CA-2248572-A1 (CA)
Title: Process and system for the ofdm multi-carrier transmission of digital radio signals
Inventor: ZIMMERMANN GERD
IPC: H04H20/00
Filed: 1997-03-05
Abstract: Improvement of an existing DAB transmission system, so that a higher net data rate can be achieved while maintaining the same system quality, or the same system quality can be achieved with a much lower signal-to-noise ratio on the receiver side at the same net data rate. A symbol mapper is connected directly downstream from a convolution encoder instead of to the block generator, as in the case of the DAB system. A multi-stage channel encoder, to which the data substreams of a source date stream are distributed, is used. The source data stream is processed on the complex symbol level and not on the bit level, as in the case of known DAB systems.
Patent CA-2249666-A1 (CA)
Title: Macrophage stimulating protein for the treatment of gastrointestinal disorders
Inventor: ZHANG KE
IPC: A61K31/00
Filed: 1997-03-25
Abstract: Methods for treating gastrointestinal tract disorders by protection, regeneration and repair of intestinal epithelium are described. Macrophage stimulating protein is found to promote colony formation by crypt cells and may be involved in stimulating proliferation of intestinal crypt cells. Also described are pharmaceutical compositions for MSP  and methods for identifying substances that stimulate crypt cell proliferation.
Patent CA-2250247-A1 (CA)
Title: A method and device for waveguide connection
Inventor: HMAN OVE
IPC: G02B6/42
Filed: 1997-03-20
Abstract: Replicated polymeric microstructures have been used in the fabrication of optofibre waveguide connections, with the intention of simplifying the production of such connections, and therewith greatly reduce manufacturing costs. Fabrication is commenced from a silicon chip in which there have been etched grooves whose cross-sectional shape has been adapted to accommodate waveguides, such as optofibres. Firstly, the silicon chip is replicated by plating the silicon chip with nickel, for instance. The replication then serves as a model for producing a plastic copy of the silicon chip. This method of manufacture is able to produce waveguide accommodating grooves (2), such as optofibre accommodating grooves, to a very high degree of accuracy.  Furthermore, the method provides a high degree of freedom in the configuration of the grooves, and also enables branched grooves for receiving branched fibres to be produced. The waveguide connection can then be used with a waveguide, such as an optofibre, together with a light transmitter or light receiver.
Patent CA-2251749-A1 (CA)
Title: Procede d'inversion des donnees de traces de reflexion provenant de releves sismiques en 3 d et 4d
Inventor: HE WEI
IPC: G01V1/30
Filed: 1997-04-28
Abstract: L'invention porte sur un procédé permettant d'inverser les données de sismique réflexion en 3D obtenues par des relevés sismiques pour en tirer des modèles d'impédances relatifs à la zone souterraine et pour inverser les différents relevés sismiques en 3D (c.-à-d. en 4D) du même volume souterrain, séparées dans le temps pour permettre la migration dynamique des fluides de manière à pouvoir déterminer la structure à petite échelle et les zones de fluides et d'écoulement de fluides dynamiques dans le volume souterrain étudié. Le procédé, qui permet de cartographier et de quantifier les hydrocarbures disponibles d'un gisement, s'avère donc utile pour la prospection des hydrocarbures et la gestion des gisements. Un schéma d'inversion sismique obtenu par itération et contraint par les données réelles de diagramme de puits et utilisant une fonction de sources sismiques dépendant de la relation temps/profondeur sert à créer des modèles d'impédance à partir d'ensemble de données sismiques en 3D et 4D. Les valeurs de l'impédance peuvent être établies par zone de manière à mieux isoler les zones pétrolifères à faible impédance. Les données d'impédance tirées des relevés sismiques en 3D multiples couvrant ce même volume peuvent être comparées pour identifier les zones d'évolution dynamique et les couches rentables déviées. On peut également tirer des données d'impédance la saturation réelle en huile ou l'épaisseur nette de la nappe d'huile en vue de son utilisation pour l'évaluation quantitative de sites prospectifs de forage et la gestion des gisements.
Patent CA-2253905-A1 (CA)
Title: Highly flavored dental floss
Inventor: OCHS HAROLD D
IPC: A61C15/04
Filed: 1998-11-10
Abstract: A highly flavored dental article for cleaning the interproximal surfaces of the teeth such as dental floss comprising one filament having a water-insoluble coating. Flavorant and a flavor enhancer are provided on the outer surface of the coating and within the depth of the coating.
Patent CA-2254005-A1 (CA)
Title: Stability control apparatus for industrial vehicles
Inventor: SUZUKI MASAKATSU
IPC: B66F9/22
Filed: 1998-11-12
Abstract: An apparatus for restricting pivoting of a pivotal axle in a forklift. The forklift has an axle that is supported pivotally relative to a body frame. A damper is arranged between the body frame and the axle to permit and restrict pivoting of the axle. An electromagnetic valve locks the damper to restrict pivoting of the axle. The axle is free to pivot when the pivot angle of the axle relative to the body frame exceeds a predetermined reference angle. A controller refers to the pivot angle and other factors relating to vehicle stability when deciding whether to restrict pivoting of the axle.
Patent CA-2254151-A1 (CA)
Inventor: NAKAMURA YASUSHI
IPC: G01N33/545
Filed: 1998-11-17
Abstract: An immunological assay method for an antigen or an antibody, which method makes use of a reaction between an immune complex resulting from a reaction between a target antigen Ag or a target antibody AbAb1 to be measured and a corresponding antibody Ab1 or antigen Ag therefor and an antibody Ab2 that specifically reacts with the antibody that has formed the immune complex, to thereby measure antigen Ag or an antibody Ab1.  The method of the present invention enables establishment of assay systems which have heretofore been impossible; i.e., immunonephelometry making use of a monoclonal antibody, latex agglutination making use of a monoclonal antibody, and hemagglutination making use of a monoclonal antibody; assay systems based on EIA or RIA, in which a single species of antibody is employed; and assay systems based on latex agglutination or hemagglutination using a trace amount of antibody.
Patent CA-2257463-A1 (CA)
Title: Novel foamable compositions for rotational molding
Inventor: LEE CLIFFORD C
IPC: C08L23/04
Filed: 1997-06-04
Abstract: Novel molding compositions consisting essentially of a mixture of a skin-forming component and a foam core-foaming component physically dry-blended together. The skin-forming component comprises two distinct phases blended together, a high zero-shear viscosity material and a low zero-shear viscosity material. The foam core-forming component preferably comprises a foamable polymeric material including a suitable blowing agent. In a preferred embodiment, the three materials are selected from suitable homopolymers and copolymers of ethylene.
Patent CA-2258135-A1 (CA)
Title: Zipperless sleeping bag
Inventor: MCPHERSON MATHEW A
IPC: A47G9/08
Filed: 1999-01-06
Abstract: A zipperless sleeping bag with a foldable flap for extra warmth and a method for making the same is provided. The sleeping bag consists of a substrate comprising three portions, a body portion, a first cover portion and a second cover portion each of which is characterized by a longitudinal and lateral length, the three portions having substantially equally lateral lengths. The first cover portion is folded over the body portion and fastened thereto along the bottom and at least a part of the side edge of the portions. At least a part of the second cover portion is folded over the first cover portion and body portion. The second cover portion serves either as a foldable flap which can be folded over the first cover portion to provide extra warmth or as the primary cover in more temperate sleeping conditions.