baber/WOPTO huggingface dataset:
Patent BR-PI9710828-B1 (BR)
Title: processo para a produção da proteína do interferon beta-cis humano recombinante e proteína de interferon beta-cis humano recombinante
Inventor: ALEX FIORINI DE CARVALHO
IPC: C12N15/70
Filed: 1997-12-18
Abstract: patente de invenção para o <b>"processo para produção da proteína do interferon beta- cis humano recombinante e proteína de interferon beta-cis humano recombinante"<d>. a presente invenção diz respeito a proteína de interferon beta-cis humano e do processo de produção da proteina beta-cis humano recombinante produzida através de técnicas de engenharia genética, para ser empregada em uso clínico humano ou veterinário ou ainda em pesquisa. o dna contendo o gene para a proteína interferon beta-cis humano foi obtido realizando-se as seguintes etapas: (1) cultivo primário de células amnióticas humanas ,(2) infecção com o vírus sendai, (3)obtenção de mrna, (4) lise das células,(5) fracionamento de rna, (6) dissolução de rna, (7) extração de rna, (8) precipitação de rna, (9) sintese de primeira fita de cdna, (10) amplificação do dna, (11) fracionamento do dna, (12) purificação do dna, (13) digestão do dna, (14) clonagem, (15) ligação do dna ao vetor, 16) transformação das bactérias competentes, (17) seleção dos clones positivos, (18) seqüenciamento dos clones, (19) produção da proteína, (20) indução da bactéria,(21) lise da bactéria,(22) purificação da proteína. sendo que a proteína de interferon beta-cis humano recombinante apresenta na sua estrutura a seguinte seqüência de aminoácidos: met-ser-tyr-asn-leu-leu-gly-phe-leu-arg-ser-ser-asn-phe-gln-cys-gln-lys-leu-leu-trp-gln-leu-asn-gly-arg-leu-glu-tyr-asp-leu-lys-asp-arg-met-asn-phe-asp-ile-pro-glu-glu-ile-lys-gln-leu-gln-gln-phe-gln-lys-glu-asp-ala-ala-leu-thr-ile-<b>cys<d>-glu-met-leu-gln-asn-ile-phe-ala-ile-phe-arg-gln-asp-ser-ser-ser-thr-gly-trp-asn-glu-thr-ile-val-glu-asn-leu-leu-ala-asn-val-tyr-his-gln-ile-asn-his-leu-lys-thr-val-leu-glu-glu-lys-leu-glu-lys-glu-asp-phe-thr-arg-gly-lys-leu-met-ser-ser-leu-his-leu-lys-arg-tyr-tyr-gly-arg-ile-leu-his-tyr-leu-iys-ala-lys-glu-tyr-ser-his-cys-ala-trp-thr-ile-val-arg-val-glu-ile-leu-arg-asn-phe-tyr-phe-ile-asn-arg-leu-thr-gly-tyr-leu-arg-asn
Patent EA-006425-B1 (EA)
Title: System for detection one or more target(s) in a sample and methods therefor
IPC: C12Q1/68
Filed: 1998-12-21
Abstract: The present invention relates to compositions, apparatus and methods useful for concurrently performing multiple, high throughput, biological or chemical assays, using repeated arrays of probes. A combination of the invention comprises a surface, which comprises a plurality of test regions, at least two of which, and in a preferred embodiment, at least twenty of which, are substantially identical, wherein each of the test regions comprises an array of generic anchor molecules. The anchors are associated with bifunctional linker molecules, each containing a portion which is specific for at least one of the anchors and a portion which is a probe specific for a target of interest. The resulting array of probes is used to analyze the presence or test the activity of one or more target molecules which specifically interact with the probes. In one embodiment of the invention, the test regions (which can be wells) are further subdivided into smaller subregions (indentations, or dimples). In one embodiment of the invention, ESTs are mapped. In another embodiment, the presence of a target nucleic acid is detected by protecting the target against nuclease digestion with a polynucleotide fragment, and analyzing the protected polynucleotide by mass spectrometry.
Patent EA-005388-B1 (EA)
Title: High functionality bowl structure
IPC: A47J27/10
Filed: 2003-03-25
Abstract: High-functionality bowl structure comprising a hollow containment body capable of containing food to be cooked or warmed, the said hollow containment body having a base, the peculiarity of which is that it comprises a thermal base fixed to the said base and capable of transmitting heat from an external heat source into the said hollow containment body.
Patent EA-007718-B1 (EA)
Title: New heterocyclic oxime compounds, a process for their preparation and pharmaceutical compositions containing them
Inventor: LECLERC VERONIQUE
IPC: C07D277/68
Filed: 2004-07-27
Abstract: Compounds of formula (I),whereinX is oxigen or sulfur atom, or a CHgroup orR, R, R, Rand Rare as defined in the specification,A is alkylene chain as defined in the specification,B is an alkyl group or an alkenyl group,substituted by a group, or R, or B is a groupor R,D is a benzene, pyridine, pyrazine, pyrimidine or pyridazine nucleus.Medicaments.
Patent EA-013425-B1 (EA)
Title: Rapid dissolution formulation of a calcium receptor-active compound
Inventor: ALVAREZ FRANCISCO J
IPC: A61K31/137
Filed: 2004-09-10
Abstract: The present invention relates to a pharmaceutical composition comprising a therapeutically effective amount of a calcium receptor-active compound and at least one pharmaceutically acceptable excipient, wherein the composition has a controlled dissolution profile. The present invention further relates to a method of manufacturing the pharmaceutical composition, as well as a method of treating a disease using the pharmaceutical composition.
Patent EA-011813-B1 (EA)
Title: Fungicidal mixtures
Inventor: TORMO I BLASCO JORDI
IPC: A01N43/653
Filed: 2005-04-23
Abstract: Fungicidal mixtures containing as active components 1) dimethylamide-3-(3-bromo-6-fluoro-2-methylindole-1-sulfonyl)-[1,2,4]triazole-1-sulfonamide of the formula IAand 2) at least one active compound selected from the group comprising: A) strobilurins: azoxystrobin, dimoxystrobin, enemtroburin, fluoxastrobin, kresoxim-methyl, metominostrobin, orysastrobin, picoxystrobin, pyra-clostrobin or trifloxystrobin; in a synergistically effective amount, a method for controlling harmful fungi, with the aid of mixtures of compound (IA) and active substances from groups A) to O), the use of compounds (I) along with active substances from groups A) for producing such mixtures, and agents containing said mixtures.
Patent EA-009720-B1 (EA)
Title: METHOD OF REGULATING CONCENTRATION OF CHARGE CARRIERS IN PbSnSe ERITAXIAL LAYERS
Inventor: PASHAEV ARIF MIRDJALALOVICH
IPC: H01L21/36
Filed: 2007-06-11
Abstract: The invention relates to semi-conductors technology and can be used in designing semi-conductor devices, in particular, to highly sensitive infrared photodetector with maximum possible high working temperatures.The inventive feature of the method for regulating concentration of charge carriers in PbSnSe epitaxial layers is characterized in that the source is the PbSnSe alloys in the range of compositions X = 0.04 – 0.12 containing additionally Cr – 0.6 at % or In – 1 at %, using a narrow range of the source temperatures 480-490°C, substrate 390-400°C and additional selenium source 102-104°C.
Patent EA-013055-B1 (EA)
Title: Use of tetramic acid derivatives for the control of insects of the plant louse species (sternorrhyncha)
Inventor: FISCHER REINER
IPC: A01N25/00
Filed: 2006-01-17
Abstract: The invention relates to the use of tetramic acid derivatives of formula (I)where A, B, G, W, X, Y and Z have the meanings given before for the control of insects of the plant louse sub-order (Sternorrhyncha).
Patent EA-014635-B1 (EA)
Title: Vapor-permeable element in the composition of soles for shoes, a sole provided with such vapor-permeable element, and a shoe with such sole
Inventor: POLEGATO MORETTI MARIO
IPC: A43B7/12
Filed: 2006-06-20
Abstract: A vapor-permeable element (10, 210, 310, 410, 510, 610) to be used in the composition of soles for shoes, which comprises: a supporting frame (11, 211, 311, 411), which delimits substantially at least one large through hole (12, 512); a membrane (17, 117) which is impermeable to water and permeable to water vapor and is arranged above the supporting frame (11, 211, 311, 411) so as to cover at least the large through hole (12, 512); at least one vapor-permeable or perforated protective layer (19) for the membrane, which is arranged between the supporting frame (11, 211, 311, 411) and the membrane (17, 117), so as to cover at least the large through hole (12, 512).The membrane (17, 117) and the protective layer (19) are joined to each other at least at their perimeter edges, and they are connected to said supporting frame (11, 211, 311, 411); the protective layer (19) with the tread of the sole to which it is attached, is available for contact with the ground during the use of the sole.
Patent EA-017880-B1 (EA)
Title: Dry decorative finishing mixture
Inventor: BASHIROV ELKHAN GIDAYAT OGLY
IPC: B28B1/00
Filed: 2009-10-27
Abstract: The invention relates to building materials based on mixed lime-cement binders and can be used for producing finishing materials, in particular to making decorative finishing articles or for facade covering. A dry mixture is claimed for making a composite material based on lime-cement binder comprising a mineral filler and aggregate, a modified polymer binder, a plasticizing agent and an iron-oxide pigment. A method is also claimed for applying a building mortar made from dry mixture using a composite material to a finishing surface and a method for producing decorative finishing articles including manual or mechanized applying of mortar, leveling and final treatment of the surface and decoration of produced pattern.
Patent EA-017541-B1 (EA)
Title: In-mold molded product coating mold and in-mold molded product coating forming method
Inventor: TODA KENICHI
IPC: B29C45/16
Filed: 2009-03-06
Abstract: There are provided an in-mold molded product coating mold and an in-mold molded product coating forming method capable of enhancing sealability for preventing any leakage of a coating agent outside of a mold. An in-mold molded product coating mold comprises: a sealing portion molding cavity (45) being positioned outside apart from a mold cavity while including a first molding surface (32) which extends from a parting surface (46) of the mold cavity (40) in a mold mating direction of a stationary mold (20) and a movable mold (30) and is formed at either one of the stationary mold and the movable mold, a second molding surface (28) which extends from the parting surface in a mold opening/closing direction of the mold cavity (40) and is formed at the other of the above-described two molds, and a third molding surface (22C); which connects the first molding surface and the second molding surface to each other, and forming a sealing portion for sealing the first and second molding surfaces by filling a resin identical to or different from a resin (J); and pressers (23) and (24) for pressing a pressing surface of the sealing portion defined by the third molding surface under a predetermined pressure, so as to bring the sealing portion into press-contact with the first and second molding surfaces, respectively.
Patent EA-020927-B1 (EA)
Title: United electrical supply device with the dc bus
Inventor: SERGEEV SERGEJ PETROVICH
IPC: H02J9/04
Filed: 2011-11-25
Abstract: The invention relates to the field of electrical engineering and can be used to supply automation equipment for railways, computer centers, centers for data processing and storage, communication centers and other low-voltage electricity consumers supplied by independent single-phase/three-phase AC power sources. Combined system includes input devices (4) of feeders (1, 2), input device for diesel-generator (5), shield of emergency shutdown feeders (6), threshold devices monitoring exceeding the permissible voltage of feeder (7), separate AC/DC voltage converters (8), a separate accumulator battery, a separate device to automatically charge the battery (12), DC trip unit, isolating diodes, DC bus (20), separate unsynchronized (synchronized) DC/AC voltage converters (11) generating single-phase/three-phase voltage, devices of an automatic entry of reserve (15) (in case of using unsynchronized DC/AC voltage converters), AC voltage converters, separate DC/DC voltage converters, protecting devices against surge and switching overvoltage (16), device (18) for collection, processing and display of control and diagnostic information about the state of elements of the unit, parameters of input feeders and output of the unit, device for management and exchange of information with supervision systems, remote monitoring and control (19). Reliability of work is assured by creating installation which allows to ensure uninterrupted power supply of the units with different specifications while feeding from several single-phase/three-phase AC power sources.
Patent EA-021783-B1 (EA)
Title: Metal receiver of intermediate ladle for continuous metal casting
Inventor: AKSEL ROD LEV MOISEEVICH
IPC: B22D41/00
Filed: 2011-12-08
Abstract: The invention relates to metallurgy and can be used, in particular, in plants for continuous metal casting. A metal receiver of an intermediate ladle for continuous metal casting comprising a capacity having a bottom (7) and a closed side wall (1) with recesses (5), further has transition parts (3) located between a zone of metal charging (8) into the metal receiver and recesses (5), each transition part being formed by two edges (6) of the closed side wall (1), which converge in the direction to the axis of the recess forming an angle β therebetween not exceeding 90°, length L of each transition part is 1.0-6.0 of the recess A length, equal to the thickness of the side wall at the recess (5) place.
Patent EA-027308-B1 (EA)
Title: Therapeutic agent for motor disorders
Inventor: UESAKA NORIAKI
IPC: C07D495/04
Filed: 2010-04-28
Abstract: Provided is a method of treating and/or preventing a movement disorder which is a side effect of L-DOPA and/or dopamine agonist therapy, comprising administering an effective amount of a thiazole derivative represented by the formula (IC) or a pharmaceutically acceptable salt thereof. Provided is the use of a thiazole derivative represented by the formula (IC) or a pharmaceutically acceptable salt thereof for the manufacture of an agent for the treatment and/or prophylaxis of a movement disorder which is a side effect of L-DOPA and/or dopamine agonist therapy.
Patent EA-024911-B1 (EA)
Title: Lactobacilli with anti-oxidant action
Inventor: GROMPONE GIANFRANCO
IPC: A61K35/74
Filed: 2010-01-08
Abstract: The present invention relates to specific Lactobacillus strains with an anti-oxidant effect.
Patent EA-025194-B1 (EA)
Title: Semisolid aqueous pharmaceutical composition containing tapentadol
Inventor: REINHOLD ULRICH
IPC: A61K31/137
Filed: 2012-03-02
Abstract: The present invention relates to a semisolid aqueous pharmaceutical composition for topical and/or local administration containing tapentadol or a physiologically acceptable salt thereof, wherein the pH value of the aqueous phase of the composition is at least 5.5. The present invention provides such a semisolid pharmaceutical composition of tapentadol which have advantages over the pharmaceutical compositions of the prior art.
Patent EA-027422-B1 (EA)
Title: Process and system for dry recovery of iron-ore fines and superfines and magnetic separation unit
Inventor: YAMAMOTO MAURO FUMYO
IPC: B03C1/30
Filed: 2013-03-13
Abstract: The invention refers to a system and method for the totally dry treatment of iron-ore wastes from previous mining operations, suitable for both the processing of ore wastes deposited in barrages and wastes stored in piles. The invention solves the problems of magnetic separation processes that employ the wet and waste-dewatering way, eliminate the risks of throwing solid wastes into retention barrages bring, wherein in this system and this method the moisture degree of the ore is reduced by means of a mechanical stir dryer using natural gas to prevent contamination, then the wastes are sorted into various fractions and finally separated magnetically, the process being entirely dry.
Patent EA-026559-B1 (EA)
Title: Compounds and compositions for inhibiting the activity of abl1, abl2 and bcr-abl1
Inventor: FURET PASCAL
IPC: C07D407/14
Filed: 2013-05-09
Abstract: The invention relates to compounds of formula (I)in which Y, Y, Y, Y, Y, R, R, Rand Rare defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.
Patent EA-026910-B1 (EA)
Title: Track tamping machine having separately stimulated vibrating tamping tines
Inventor: HOFSTAETTER JOSEF
IPC: E01B27/16
Filed: 2013-09-27
Abstract: A tamping unit (2) of a machine for simultaneously tamping at least two sleepers (9) of a track (3), positioned one following the other with regard to a longitudinal direction (10) of the machine, has inner tamping tines (20) provided for simultaneous immersion into the same sleeper crib (18) and an outer tamping tine (19) at each end. Each tamping lever (14) mounted on a unit frame (11) so as to be pivotable about a pivot axis (13) is connected to a squeeze drive (15). Each squeeze drive (15) is mounted on a common eccentric shaft (21) having an eccentricity with respect to an axis of rotation (16). The eccentricity causing vibrations of the inner tamping tine (20) is configured differently as compared to the eccentricity causing vibrations of the outer tamping tine (19).
Patent EA-027610-B1 (EA)
Title: Method of mixing and grinding materials
Inventor: AFANASIEV ALEKSEY GAVRIILOVICH
IPC: B22C5/04
Filed: 2015-07-07
Abstract: The invention is related to grinding and mixing methods using centrifugal techniques and is designed for dry and wet grinding and mixing of materials in the form of lumps, grains or powders, and for preparation of mixtures used in various sectors of industry. A materials mixing and grinding method wherein grinding bodies and material to be ground are loaded into a rotatable working container on the inner surface of which a layer of ground material and grinding bodies is formed under action of centrifugal forces and processed by an immobile or rotating blade, wherein grinding bodies are separated by at least one blade from the ground material layer and guided to the wall of the working container, and the ground material is passed through slots and/or holes in the blade, the ground material passing through slots and/or holes in the blade is shifted along the working container rotation axis. The invention provides higher productivity of the grinding and mixing process, a shorter duration of the processing cycle, and a higher degree of dispersion (grinding fineness) of ground material.
Patent EA-031620-B1 (EA)
Title: Device for removal of blood vessel obstruction
Inventor: KHRUSTALEV BORIS MIKHAILOVICH
IPC: A61B17/3203
Filed: 2015-10-28
Abstract: The device relates to articles of medical equipment, and more particularly to devices for removal of blood vessel obstruction. The task of the invention is to enhance the efficiency of intravascular mass destruction and also to improve convenience of use. The set task is solved by suggesting a device for removal of blood vessel obstruction containing an ultrasonic oscillation generator, an ultrasonic transducer and a connected with it concentrator-waveguide connected with a liquid supply or aspiration line and made in the form of a stepped cylindrical tube with an internal hole with an olive-shaped working head formed on the distal end.
Patent EA-031149-B1 (EA)
Title: Animal protection system and arrangement
Inventor: STOLARSKI MAREK
IPC: A01M29/16
Filed: 2015-03-03
Abstract: The present invention relates to a system for the animal protection, emitting warning sound sequences and comprises at least one KUOZ container (2) of animal protection device connected to the at least one UOZ animal protection device (1). In addition, the KOUZ container (2) of animal protection device is connected with at least one SPS control device (24). The invention also relates to an animal protection arrangement comprising an acoustic transducer (5) connected to the memory (7) with acoustic signals. The memory (7) with acoustic signals is connected to an internal control circuit (8) which communicates with a device (9) for monitoring rail traffic. In addition, the internal control circuit (8) is connected to a KUOZ container (2) of the animal protection device, which is connected to at least one SPS control device (24).
Patent EA-032889-B1 (EA)
Title: Options to reduce product fouling in mto downstream recovery
Inventor: SENETAR JOHN J
IPC: C07C11/02
Filed: 2015-05-12
Abstract: A process is presented for removing the fouling problems associated with the product recovery in a methanol to olefins conversion process. The process includes passing the quenched methanol to olefins (MTO) process stream to a product separator, wherein an intermediate stream is generated and includes water and heavier hydrocarbons. The intermediate stream is processed to remove the buildup of heavier hydrocarbons.
Patent EA-034508-B1 (EA)
Title: Rail vehicle, method for driving said rail vehicle and method for producing said rail vehicle
Inventor: FORRER DANIEL
IPC: B61D3/02
Filed: 2016-02-29
Abstract: Provided are a rail vehicle (1), a method for producing and a method for driving the rail vehicle (1) which comprises at least one car body (2). The car body (2) comprises two car body ends (3, 4), each end region of which is supported on a respective wheel unit (5, 6). At least one wheel unit (5, 6) is designed to be driven. The rail vehicle further comprises a drive arrangement, wherein the drive arrangement comprises at least one transformer unit (7), at least one traction motor unit (9) and at least one power converter unit (8). The primary transformer unit (7) and the primary power converter unit (8) are arranged in the region of the first wheel unit (5). The primary transformer unit (7) and the primary power converter unit (8) are connected to the wheel unit (6) such that the traction motor unit (9) can be driven by the primary transformer unit (7) and the primary power converter unit (8).
Patent EA-035821-B1 (EA)
Title: Method and data entry device for the entry of data in electrical form
Inventor: BALINT GEZA
IPC: G06F3/0338
Filed: 2015-11-05
Abstract: Described herein is a method for the conversion of elementary finger movements and/or movement combinations of a user into respective characters and/or functions presented as electrical signals by using a hand held smart electronic including the steps of associating a group of the movements or movement combinations with respective ones of characters and/or functions prior to the beginning of the conversion step so that the movements take place in a region defined by a closed boundary line; in the associating step defining a predetermined number of special positions along the boundary line of the permitted region of movement; entering the required characters and/or functions in a consecutive sequence further including the steps of holding the device in a hand so that a free finger touches an upper surface thereof; moving the finger according to the movements or movement combinations associated with the character or function to be entered; providing haptic feedback to the user when the boundary line and any of the special positions has been reached; following the termination of the entry of a character or function slightly raising the finger, detecting the finger raising step and carrying out the conversion of the previously entered movement combination into the associated character or function; repeating the entering steps as long as all required characters or functions have been entered and converted.