baber/WOPTO huggingface dataset:
Patent CA-3002695-A1 (CA)
Inventor: WANG PENGFEI
IPC: C07C251/24
Filed: 2016-10-21
Abstract: The invention discloses a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, and a preparation method and application thereof. The amphiphilic hypocrellin derivative substituted by a group containing PEG, a quaternary ammonium salt or the like prepared according to the invention has an obvious red shift in its absorption spectrum and a significantly enhanced molar extinction coefficient, compared with the parent hypocrellin, can efficiently produce singlet state oxygen and other reactive oxygen species under photosensitive conditions; has different amphiphilicities and increased biocompatibility with cells or tissues by regulating its hydrophilicity and hydrophobicity; can meet the requirements of different clinical drugs, and solves the requirements of different drug delivery methods for different drug hydrophilicity and lipophilicity. Under identical conditions, the amphiphilic hypocrellin derivative photosensitizer according to the invention has higher ability to photodynamically inactivate tumor cells than the first and second generation commercial photosensitizers.
Patent CA-3003262-A1 (CA)
Title: Spexin-based galanin receptor type 2 agonists and use thereof
Inventor: SEONG JAE YOUNG
IPC: C07K7/08
Filed: 2016-11-30
Abstract: The present invention relates to an agonist of spexin-based galanin type 2 receptor and a use thereof. More specifically, the present invention provides a peptide-based agonist having improved specificity and stability to the galanin type 2 receptor, wherein the peptide-based agonist is involved in the regulation of physical functions in the body, such as feeding, anxiety, emotion, and addiction, in which the galanin type 2 receptor plays a role, thereby suppressing appetite, relieving anxiety disorders, and reducing the addiction to pleasure, and thus, the peptide-based agonist can be used to prevent or treat diseases induced by galanin type 2 receptor .
Patent CA-3005670-A1 (CA)
Inventor: CORDOVA ARMANDO
IPC: C08L1/26
Filed: 2016-11-23
Abstract: The present disclosure relates to the environmentally preparation of nanocellulose and derivatives thereof. The invention further relates to the preparation of cellulose derivatives.
Patent CA-3007977-A1 (CA)
Title: Procede et systeme de mesure pour l'acquisition et le traitement de donnees dans des etudes de tomographie a champs doux
Inventor: BORBAS KAROLY
IPC: A61B5/053
Filed: 2016-12-14
Abstract: L'invention concerne un système de mesure pour l'acquisition de données lors de l'analyse, par tomographie à champs doux, d'un objet, le système de mesure comprenant une unité de commande connectée à une unité d'excitation et à l'unité d'acquisition de données de mesure. L'unité d'excitation est connectée à une unité d'émission qui est couplée à l'objet étudié afin de créer un champ d'excitation dans l'objet. Les unités de réception sont couplées, une par une, à l'objet étudié et sont interconnectées par paires pour former des circuits de mesure afin de caractériser la réponse de l'objet détectée par les unités de réception en raison du champ d'excitation. Chacun des circuits de mesure comprend une unité de mesure présentant au moins une première et une deuxième entrée de mesure connectées aux première et deuxième unités de réception des circuits de mesure. Les unités de mesure de chaque circuit de mesure sont connectées à l'unité d'acquisition de données de mesure pour acquérir les données de mesure.
Patent CA-3009378-A1 (CA)
Title: Oligomeres d'acides nucleiques et leurs utilisations
Inventor: RICHARD DEREK
IPC: A61P35/00
Filed: 2016-12-23
Abstract: L'invention concerne des composés oligomères d'acide nucléique et leur utilisation dans des compositions et des procédés pour inhiber la prolifération, la survie ou la viabilité de cellules cancéreuses notamment les cellules cancéreuses de la prostate, du poumon, du pancréas, du sein, du col de l'utérus et des os.
Patent CA-3010524-A1 (CA)
Inventor: ARBESMAN RAY
IPC: B21D28/26
Filed: 2018-07-05
Abstract: A material includes a sheet of metal having a first face and an opposed second face, and a metal grain direction. The first face is textured with a first set of texturing features. Each texturing feature of the first set includes, respectively, a groove cut into the first face and extending along a groove axis, and a barb extending from the groove and away from the first face. The texturing features of the first set are arranged in a plurality of rows, and the groove axes of the texturing features in a given row extend generally parallel to the given row. The rows are generally non-perpendicular to the grain direction.
Patent CA-3010845-A1 (CA)
Inventor: GOLDAN AMIRHOSSEIN
IPC: H01L31/0376
Filed: 2017-01-09
Abstract: L'invention concerne un photomultiplicateur à puits multiples et à conformation de champ et son procédé de fabrication. Le photomultiplicateur comprend un détecteur à avalanche à puits multiples et à conformation de champ, comprenant un isolant inférieur, une couche photoconductrice a-Se et un isolant supérieur. La couche photoconductrice a-Se est positionnée entre l'isolant inférieur et l'isolant supérieur. Une région d'interaction de lumière, une région d'avalanche et une région de collecte sont disposées sur la longueur du photomultiplicateur et la région d'interaction de lumière et la région de collecte sont positionnées de chaque côté de la région d'avalanche.
Patent CA-3012669-A1 (CA)
Inventor: LIEN HUNG MEI
IPC: F24C1/02
Filed: 2018-07-27
Abstract: The present application discloses a multi-functional oven, including: a main oven body, an upper cover assembly rotatably connected with the main oven body, a charcoal tray having a plurality of through holes and arranged in the main oven body, , a grill disposed above the charcoal tray, a pellet stove assembly cooperating with the charcoal tray, and a gas oven assembly matching with the charcoal tray; the pellet stove assembly comprises a pellet burner located below the charcoal tray and a pellet feeding mechanism for conveying granular fuel to the pellet burner; the gas oven assembly comprises a gas burner located below the charcoal tray, and a gas supply device matching with the gas burner. Which can achieve using charcoal oven mode, pellet stove mode or gas oven mode for barbecuing, therefore, the barbecue oven has a variety of grilling modes.
Patent CA-3012728-A1 (CA)
Title: Dynamic noise mitigation device
Inventor: ALKAN ERDOGAN
IPC: H04B1/10
Filed: 2017-01-27
Abstract: The present disclosure provides methods and systems for mitigating signal noise. In implementations, the systems and methods perform operations including continuously determining an instantaneous power of a signal path. The operations also include determining a dynamic noise threshold by sampling the instantaneous power at different times and selecting a minimum of the instantaneous power sampled during the different times. The operations further include determining that the instantaneous power is less than the dynamic noise threshold. Additionally, the operations include blocking communication from the signal path. Further, the operations include iteratively updating the dynamic noise threshold.
Patent CA-3012920-A1 (CA)
Title: Methode de fabrication d'un module de lubrification d'une turbomachine
Inventor: CHENOUX MATHIEU
IPC: F01D25/20
Filed: 2018-07-31
Abstract: Une unité de lubrification de moteur de turboréacteur à double flux daéronef comprend de trois à cinq pompes superposées, et un corps logeant les pompes et comprenant un passage interne communiquant avec chacune des pompes. Le matériau du corps présente un empilement de couches dans un sens de lempilement, les pompes étant logées dans cet empilement. Le passage présente une extrémité dans le sens de lempilement des couches et un profil interne, par exemple triangulaire, avec deux lignes droites formant ladite extrémité et étant inclinées par rapport aux couches empilées. La production de lunité de lubrification comporte une fabrication additive en couches.
Patent CA-3013169-A1 (CA)
Title: Optical-fiber-compatible acoustic sensor
Inventor: AKKAYA ONUR CAN
IPC: G03F7/00
Filed: 2011-03-14
Abstract: An acoustic sensor system comprises a first acoustic sensor, a second acoustic sensor and a reservoir. The first acoustic sensor comprises a first reflective element and a first optical fiber positioned relative to the first reflective element such that light emitted from the first optical fiber is reflected by the first reflective element. An end of the first optical fiber and the first reflective element form a first optical cavity therebetween, comprising a liquid medium. The second acoustic sensor comprises a second reflective element and a second optical fiber positioned relative to the second reflective element such that light emitted from the second optical fiber is reflected by the second reflective element. An end of the second optical fiber and the second reflective element form a second optical cavity therebetween, comprising the liquid medium. The reservoir comprises the liquid medium and is in fluidic communication with the first and second optical cavities.
Patent CA-3014435-A1 (CA)
Inventor: KAWAOKA YOSHIHIRO
IPC: A61K39/145
Filed: 2017-02-17
Abstract: The invention provides a composition useful to prepare high titer influenza B viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza B virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, that confer enhanced growth in cells in culture, such as MDCK cells, or in eggs.
Patent CA-3014744-A1 (CA)
Inventor: GARAK JUSTIN
IPC: H03M13/00
Filed: 2017-02-07
Abstract: A first real-time content filter and a second real-time content filter are stored, the first real-time content filter being associated with a first predetermined limited input, and the second real-time content filter being associated with a second predetermined limited input, the first predetermined limited input being different from the second predetermined limited input. Content is captured of a subject, the content comprising video content. A first limited input is received. It is determined whether the first limited input matches any of the first predetermined limited input or the second predetermined limited input. The first real-time content filter is selected responsive to a determination the first limited input matches the first predetermined limited input. The content is edited using the first real-time content filter while the content is being captured.
Patent CA-3014792-A1 (CA)
Title: Compositions permettant d'ameliorer l'edition ciblee de genes et leurs procedes d'utilisation
Inventor: SALTZMAN W MARK
IPC: C07K14/00
Filed: 2017-02-16
Abstract: L'invention concerne des compositions et des procédés permettant d'améliorer l'édition ciblée de gènes et leurs procédés d'utilisation. Dans les modes de réalisation préférés entre tous, l'édition de gènes s'effectue à l'aide d'une composition d'édition de gènes comprenant par exemple des oligonucléotides formant des triplex, CRISPR, des nucléases à doigt de zinc, TALENS, ou autres, en combinaison avec un agent de potentialisation de modification de gène tel que le facteur de cellule souche (SCF), un inhibiteur de CHK1 ou d'ATR, ou une combinaison de ceux-ci. Une composition d'édition de gènes particulièrement préférée comprend des acides nucléiques peptidiques formant des triplex (PNA) substitués à la position ? pour améliorer l'affinité de liaison à l'ADN. Des compositions de nanoparticules destinées à l'administration intracellulaire de ladite composition d'édition de gènes et leurs avantages particuliers pour une utilisation dans des applications in vivo sont en outre décrits.
Patent CA-3015790-A1 (CA)
Title: A condition-responsive wearable device for sensing and indicating proximity of an article with a specific characteristic
Inventor: MOSSOBA MICHAEL BAKR
IPC: G08B21/02
Filed: 2018-08-29
Abstract: A condition-responsive wearable device for sensing and indicating proximity of an article with a specific characteristic includes a processor and a sensor.  The sensor is configured to detect an article with two or more information sources within a predetermined distance of the sensor. The information sources contain characteristic information of the article. The wearable device also includes a memory storing instructions that, when executed by the processor, cause the processor to receive predefined characteristic information, select detected characteristic information from at least two of the information sources to compare with the predefined characteristic information, and compare the selected detected characteristic information with the predefined characteristic information. The wearable device includes an indicator configured to generate an alarm in response to detecting a match between the selected detected characteristic information and the predefined characteristic information.
Patent CA-3016503-A1 (CA)
Title: Tool for facilitating removal of a broken exhaust manifold stud from a cylinder head and method of using same
Inventor: Roberto Marco
IPC: B23K37/04
Filed: 2018-09-05
Abstract: A tool for facilitating removal of a broken exhaust manifold stud from a cylinder head. The tool includes an aperture receiving a nut element thereinto and a mounting aperture. The tool is configured so that when a protruding exhaust manifold stud in received in the mounting aperture, the nut can be positioned adjacent the broken exhaust manifold stud for welding the latter and the former together.
Patent CA-3016842-A1 (CA)
Inventor: CAMBRUZZI ANDREA
IPC: B66B19/00
Filed: 2017-03-28
Abstract: The invention relates to a method and a mounting device for carrying out an installation operation in a lift shaft of a lift system. In the method according to the invention, a first elongate reference element (110) is introduced into the lift shaft (103) and oriented in a main direction of extent (108) of the lift shaft (103). In addition, a mounting device (1) is introduced into the lift shaft (103), which mounting device has a carrier component (3) and a mechatronic installation component (5) held by the carrier component (3). This mounting device (1) is displaced into a fixing position in the main direction of extent (108) of the lift shaft (103). The relative position of the carrier component (3) of the mounting device (1) is determined with respect to the first reference element (110) in the fixing position, with a sensor arranged on the installation component (5) being used for this purpose. The relative position of the first reference element (110) is determined with respect to at least two different sensor positions and thus positions of the installation component (5).
Patent CA-3020138-A1 (CA)
Title: Insecticidal cry toxins
Inventor: NARVA KENNETH E
IPC: A01N63/02
Filed: 2017-04-04
Abstract: Insecticidal toxins derived from Bacillus thuringiensis, polynucleotides encoding such toxins, use of such toxins to control Coleopteran plant pests, and transgenic plants that produce, and are protected, by these toxins are described.
Patent CA-3021376-A1 (CA)
Inventor: MASSEY JUSTIN
IPC: C02F1/32
Filed: 2016-04-25
Abstract: A UV disinfectant system may include a chamber having a wall that is transparent to a disinfecting radiation. Liquid may be flowed through the chamber for treatment by exposure to the radiation. The chamber may include a static mixer having vanes to impede laminar flow of the liquid during treatment. The vanes extend into the flow path of the liquid through the chamber. A gap is defined between the vanes and the transparent wall. A cabinet may house the chamber and radiation emitting bulbs. Blowers may be operably coupled to a temperature sensor and flow meter and positioned at a lower end and upper end of the cabinet to urge air out of the cabinet. The temperature sensor may include a thermocouple. The blowers may be variable speed blowers. The system may include a controller to control system operations. The controller may be remotely accessible to monitor or control operations.
Patent CA-3022164-A1 (CA)
Inventor: ZEMLOK MICHAEL
IPC: A61B90/00
Filed: 2017-05-23
Abstract: La présente invention décrit un support d'instrument chirurgical comprenant un chariot, un logement, et un ensemble entraînement. Le chariot est configuré pour la mise en prise avec un bras robotique chirurgical et pour soutenir une unité d'entraînement d'instrument. Le logement s'étend depuis le chariot et définit un canal. L'ensemble entraînement comprend une poulie, une courroie, et un élément annulaire. La poulie est disposée de manière à pouvoir tourner à l'intérieur du logement et en prise de manière fonctionnelle avec un moteur du chariot de sorte que l'actionnement du moteur fait tourner la poulie. La courroie est disposée de manière à pouvoir tourner à l'intérieur du logement et en prise de manière fonctionnelle avec la poulie de sorte que la rotation de la poulie effectue la rotation de la courroie. L'élément annulaire est disposé à l'intérieur du canal du logement et configuré pour la réception de manière non rotative d'une unité d'entraînement d'instrument. L'élément annulaire se trouve en prise de manière fonctionnelle avec la courroie de sorte que la rotation de la courroie effectue la rotation de l'élément annulaire.
Patent CA-3026334-A1 (CA)
Inventor: ISMAN MARSHALL A
IPC: G06F9/445
Filed: 2017-05-18
Abstract: A method includes analyzing, by a processor, a first version of a computer program, the analyzing including identifying a first process included in the first version of the computer program, the first process configured to perform an operation on data having a first format; and by a processor, generating a second version of at least a portion of the computer program, including omitting the first process and including in the second version of the at least portion of the computer program one or more second processes configured to perform a second operation on data of a second format different from the first format, wherein the second operation is based on the first operation.
Patent CA-3027468-A1 (CA)
Inventor: KIEKENS FILIP
IPC: A61K47/12
Filed: 2017-06-29
Abstract: La présente invention concerne le domaine de la conservation de micro-organismes, et en particulier un système à deux compartiments comprenant un premier compartiment comprenant des microcapsules avec des micro-organismes dans une composition non aqueuse dans le noyau desdites microcapsules, et un second compartiment contenant de l'acide organique aqueux. L'invention concerne en outre des procédés de conservation de micro-organismes, sur la base de ces systèmes, ainsi que des utilisations de ces systèmes pour la conservation de micro-organismes.
Patent CA-3028002-A1 (CA)
Inventor: TAREEN SEMIH U
IPC: C12Q1/68
Filed: 2017-06-27
Abstract: La présente invention concerne des procédés d'identification d'épitopes peptidiques d'une molécule de complexe majeur d'histocompatibilité (CMH) d'un antigène, tel qu'un antigène tumoral, un antigène auto-immun ou un antigène pathogène. Selon certains modes de réalisation, les procédés concernent l'utilisation d'un cytomégalovirus incluant une molécule d'acide nucléique codant pour l'antigène en vue d'infecter des cellules dans des conditions en vue de générer des épitopes peptidiques particuliers de l'antigène. L'invention concerne également des procédés d'identification de molécules de liaison de peptide qui se lient à un épitope peptidique dans le contexte d'une molécule de CMH. Selon certains modes de réalisation, la molécule de liaison de peptide est un récepteur de lymphocyte T (TCR) ou un anticorps, y compris des fragments de liaison à l'antigène de celui-ci et des récepteurs d'antigène chimériques (CAR) de ce dernier. L'invention concerne également des procédés de génie génétique de cellules incluant de telles molécules de liaison de peptide, et de telles cellules génétiquement modifiées, y compris des compositions et leurs utilisations en thérapie cellulaire adoptive.
Patent CA-3030869-A1 (CA)
Inventor: GROSECLOSE DENNIS WILLIAM
IPC: G01C21/20
Filed: 2017-07-18
Abstract: Methods and systems and method of tracking the location of an object. The method includes assigning a unique first device identifier, associating the first device with an object, and storing the unique identifier and an identifier for the object associated with the first device in a location server. The method also includes transmitting a first message containing the unique identifier, but not the first device location, receiving the first message at a second device, and transmitting a second message from the second device containing the unique identifier and a second device location. The method also includes, at the location server, receiving the second message, associating the location of the second device with the first device, storing the location of the second device, receiving a request for the location of the object, and in response to the request, providing the uni ue identifier and the second device location.
Patent CA-3033886-A1 (CA)
Inventor: LIMAN MARTIN
IPC: C12N7/00
Filed: 2017-08-14
Abstract: The invention relates to agents, compositions, uses and methods for a novel variant of the infectious bronchitis virus (IB-virus).
Patent CA-3034833-A1 (CA)
Inventor: PERSON TIMOTHY J
IPC: C09D7/63
Filed: 2011-09-23
Abstract: Les compositions polymères ci-décrites ont une tenue diélectrique améliorée. Ces compositions polymères contiennent une polyoléfine et un agent pour stabiliser la tension. Lagent pour stabiliser la tension est un diphénoxybenzène et/ou un benzanilide. Les présentes compositions polymères manifestent une teneur diélectrique améliorée quand elles sont appliquées à titre de couche isolante sur un câble dalimentation.
Patent CA-3036981-A1 (CA)
Title: Electrical insulation system based on epoxy resins for generators and motors
Inventor: BEISELE CHRISTIAN
IPC: H01B3/04
Filed: 2017-09-25
Abstract: Disclosed is an anhydride-free insulation system for current-carrying construction parts of an electric engine which comprises: (A) a mica paper or mica tape for wrapping parts of said electric engine that are potentially current-carrying during operation of the engine, which mica paper or mica tape is impregnable via vacuum pressure impregnation with a thermally curable epoxy resin formulation and comprises a complex of boron trihalogenide with an amine of the formula BX3 . NR1R2R3 or R1R2N-A-NR1 R2, wherein X denotes halogen, R1, R2 and R3 are each independently of the others hydrogen, C1-C12alkyl, C5-C30aryl, C6-C36aralkyl or C6-C14cycloalkyl, which can be unsubstituted or substituted by one or more C1- C12alkyl groups, A is a bivalent aliphatic aromatic or cycloaliphatic radical; (B) a thermally curable bath formulation for the vacuum pressure impregnation comprising bisphenol A diglycidyl ether and optionally bisphenol F diglycidyl ether, which formulation is substantially or, preferably, entirely free of thermally activatable curing initiators for the epoxy resin formulation.
Patent CA-3038520-A1 (CA)
Inventor: KUMAR SANDEEP
IPC: A01H5/10
Filed: 2017-09-08
Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a Panicum virgatum (Pavir.J00490) egg cell gene. Some embodiments relate to a promoter from a Panicum virgatum (Pavir.J00490) egg cell gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3' UTR from a Panicum virgatum (Pavir.J00490) egg cell gene that functions in plants to promote transcription of operably linked nucleotide sequences.
Patent CA-3039426-A1 (CA)
Title: Multifunctional zwitterionic polymer conjugates
Inventor: CHARLES STEPHEN A
IPC: C08F230/02
Filed: 2010-12-20
Abstract: CA3039426 ABSTRACT The disclosure pertains to random copolymer having the formula: Rs re r y' = (6121n RI Random copolymers as disclosed may be useful in preparing conjugates of biologically active agents. Date Regue/Date Received 2023-02-07