baber/WOPTO huggingface dataset:
Patent DE-69331643-D1 (DE)
Inventor: KEMPF DALE J
IPC: C07D413/12
Filed: 1993-12-16
Granted: 2002-04-04
Abstract: A retroviral protease inhibiting compound of formula (A) is disclosed for use in combination with other active pharmaceutical agents for treating a human infected by HIV. Intermediates and processes useful in the manufacture of compounds of formula (A) are also disclosed. <CHEM>
Patent DE-69332373-D1 (DE)
Inventor: POLAKOWSKA REGINA
IPC: C07H21/04
Filed: 1993-01-22
Granted: 2002-11-14
Abstract: The present invention relates to promoter elements from human type I transglutaminase (TGase I) genes for controlled gene expression of both human TGase I and heterologous proteins. These promoter elements permit tissue-specific expression of genes, e.g. for use in human gene therapy and for testing pharmaceutical agents with artificial skin. Additionally, the subject promoter elements can provide differential regulation under physiological conditions or in the presence of exogenously added factors including calcium and retinoic acid.
Patent DE-69408334-D1 (DE)
Inventor: GREENHALGH GEOFFREY
IPC: B29C35/16
Filed: 1994-10-11
Granted: 1998-03-05
Abstract: The invention relates to edge encapsulation of a glazing panel (20), e.g. for a vehicle. To allow satisfactory setting of a thin section (23), e.g. a lip, of an encapsulation (22) by radio frequency dielectric heating in a low cost, non-metallic mould operated at low injection pressures, the invention provides a mould (36) comprising a mould body composed of dielectric material shaped to receive the glazing panel (20), the mould body defining an elongate cavity (73) for receiving a liquid encapsulating material, which, in use, surrounds an edge portion of the glazing panel (20), characterised in that an electrically polarizable field shaping element (75) is provided within the mould body.
Patent DE-69411422-D1 (DE)
Inventor: NIEMINEN JUHA
IPC: B66B5/00
Filed: 1994-03-15
Granted: 1998-08-13
Abstract: The invention relates to a procedure for supplying and modifying the data required in the control system of an elevator and for displaying the instructions needed for installation, maintenance and adjustment on a display (13) comprised in the control system. According to the invention, the parameter data of the elevator control system and the instructions for each person carrying out maintenance work are stored in a separate storage unit (17). When modification or maintenance work is being carried out, a communication link is established between the storage unit (17) and the data storage means of a control unit (1) comprised in the control system, the data stored in the storage unit (17) is read and saved in the control unit (1) and the modifications and actions required by the data read from the storage unit (17) are carried out in the control unit (1). <IMAGE>
Patent DE-69416551-D1 (DE)
Inventor: GARCIA SALVADOR
IPC: B41J2/355
Filed: 1994-08-03
Granted: 1999-03-25
Abstract: Thermal printer with line head comprising a plurality of printing heating elements (2) designed, under the control of individual activation means (7, 8) and by means of memory dots (6; 46) of a printing register (5; 45), to print successive lines of dots on a support to be printed which is driven in transit against the head (1), the said printer being characterised in that it comprises means (10; 40) for the individual character addressing of the memory dots (6; 46). - Use in facsimile machines. <IMAGE>
Patent DE-69417241-D1 (DE)
Inventor: PEETERS ALEXANDER
IPC: F02B3/06
Filed: 1994-08-23
Granted: 1999-04-22
Abstract: PCT No. PCT/NL94/00199 Sec. 371 Date Feb. 26, 1996 Sec. 102(e) Date Feb. 26, 1996 PCT Filed Aug. 23, 1994 PCT Pub. No. WO95/06196 PCT Pub. Date Mar. 2, 1995In a gas combustion engine, which is manufactured by conversion of a diesel engine, the piston shape, the compression ratio, the air intake system and the exhaust gas system are modified. The exhaust gas system is split into two parts, each of which consists of an exhaust branch-piece and a catalyser, whereby catalysers of standard format can be employed, and the air intake system is made smaller, whereby the probability of backfire is reduced. The hollow in the piston already present in the diesel engine is enlarged in diameter and depth, in such a manner that the ratio of the diameter to the depth is equal to 30:11. In this manner, one achieves an optimal form with respect to heat extraction. In addition, enlargement of the hollow causes a lowering of the compression ratio to a value of 1:10, which is necessary when applying gas as a fuel. In addition, the edge of the piston near the top surface of the piston is bevelled, in order to compensate for extra expansion of the piston around the hollow, which extra expansion occurs as a result of the increased combustion temperatures. The costs of the above-specified conversion of a diesel engine to a gas combustion engine are hardly higher than those of a revision service of a diesel engine, so that there is no longer a financial obstacle to conversion to gas as a fuel.
Patent DE-69426804-D1 (DE)
Inventor: BEAVO JOSEPH A
IPC: C12N1/21
Filed: 1994-05-27
Granted: 2001-04-12
Abstract: The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides. <IMAGE>
Patent DE-69429178-D1 (DE)
Inventor: WIRKUS ANDREW
IPC: E04G21/18
Filed: 1994-08-15
Granted: 2002-01-03
Abstract: A glass brick wall (1) comprising a plurality of generally rectangular glass bricks (2) layed in horizontal runs between spaced elongated vertically extending support frame members (3), the wall having horizontally extending elongated separation strips (4) between adjacent horizontal runs, characterised in that, the vertical support frame members (5) present a face incorporating vertically spaced apertures (9) receiving said separation strips (4). <IMAGE>
Patent DE-69430071-D1 (DE)
Inventor: MITTAL K
IPC: C12N7/01
Filed: 1994-12-09
Granted: 2002-04-11
Abstract: The present invention relates novel live bovine adenovirus (BAV) expression vector systems in which part or all of one or both of the early region 1 (E1) and early region 3 (E3) genes are deleted and replaced by a foreign gene or fragment thereof and novel recombinant mammalian cell lines stably transformed with BAV E1 sequences, and therefore, express E1 gene products capable of allowing replication therein of a bovine adenovirus having an E1 deletion replaced by a heterologous nucleotide sequence encoding a foreign gene or fragment thereof and their use in production of (antigenic) polypeptides or fragments thereof for the purpose of live recombinant virus or subunit vaccine or for other therapies.
Patent DE-69430243-D1 (DE)
Inventor: FORTIER GUY
IPC: C08J3/075
Filed: 1994-11-24
Granted: 2002-05-02
Abstract: Novel bioartificial hydrogels consisting of a three-dimensional crosslinked mixture of: (a) a bifunctionalized polyethylene oxide, activated with an activating agent, dissolved in an aqueous solution; and (b) albumin type protein. The novel hydrogels are based on the crosslinking of albumin type protein of various sources including, for example, bovine serum albumin, lactalbumin or ovalbumin, with a bifunctionalyzed polyethylene oxide, most preferably polyethylene glycol, or a mixture of bifunctionalyzed polyethylene oxides preferably polyethylene glycol, of various molecular masses (Mr 2,000 to 35,000), dissolved in aqueous solution in adequate proportions. Also provided is a method and conditions for preparing the novel hydrogels. Also divulged are a variety of biomedical applications for the novel hydrogels. Additionally, it has been found that the mechanical properties of the novel hydrogels can be improved by adding to the casting solution unreactive polyethylen glycol or other inert polymer of high molecular masses (Mr>100,000). In general terms the novel hydrogels possess advantageous properties such as shape retention and shape memory, high water content (more than 94% (w/w) based on the dry weight of the hydrogel), good mechanical and optical properties.
Patent DE-69430746-D1 (DE)
Inventor: MCANALLEY H
IPC: A61L15/28
Filed: 1994-06-22
Granted: 2002-07-11
Abstract: A therapeutic medical device is described that is comprised of a dried hydrogel of a hydrophilic-hygroscopic polymer, such as an unmodified or modified polymeric carbohydrate, in the form of a solid foam. The dried hydrogel is prepared by preferably freeze-drying a hydrogel of this polymer in a liquid medium, such as water. The dried hydrogel can be sterilized by radiation or other means so that the sterilized product has a relatively indefinite shelf-life without refrigeration. The resultant dried hydrogel can be transformed into a hydrogel upon absorption of addition liquid medium. The described therapeutic device can serve as a dressing for a wound or lesion, drug delivery system, a hemostatic agent and a biologic response modifier. The described therapeutic device enhances the wound healing rate.
Patent DE-69500617-D1 (DE)
Inventor: HAEMMERLIN BERNARD
IPC: B62B5/02
Filed: 1995-12-20
Granted: 1997-10-02
Abstract: The two wheeled hand cart comprises a tubular chassis formed by two longitudinal side members (1,2) connected by two transverse struts (3,7). The side members carry at their front lower ends a loading plate (4). Above these lower ends are a pair of vertical webs (5,6) which support wheels. A main horizontal axle passes through the lower strut (7) on the ends of which are mounted , outside the webs, horizontal parallelogram shaped finned pivots (11,12). The sides parallel to these pivots (13,14) act, during their rotation, as axles (15,16) for the wheels (17,18). At rest, or in the absence of obstacles, the wheel axles are located in the plane vertical with and above the principal axle. When in contact with an obstacle , under the effect of the rearwards pull caused by the cart, the fins tip frontwards around the principal axle, in the direction of the loading plate. The wheels are thus driven frontwards and downwards and can then roll easily upwards along the obstacle. The cart can easily roll up and over obstacles in its path.
Patent DE-69511826-D1 (DE)
Inventor: AARTS MATHIAS LEONARDUS CORNEL
IPC: B65B31/02
Filed: 1995-11-22
Granted: 1999-10-07
Abstract: Method and apparatus for evacuating a vacuum package made from a thin-walled and flexible packaging material and filled with granular material. An open end of a filled package is folded in such a manner that a narrow gap is formed which constitutes an open communication between an interior and an exterior of the package. At least a part of the package is placed in a vacuum space and vacuumized for removing gasses from the package through the gap. Upon evacuation the package is sealed airtightly. Further, on at least a part of the packaging material defining the gap a force is exerted which reduces the gap width, so that the gap constitutes a filter for the granular material, whereby the granular material is retained inside the package during the evacuation of the package. <IMAGE>
Patent DE-69524105-D1 (DE)
Inventor: SOOKNANAN ROY
IPC: C12Q1/6865
Filed: 1995-07-13
Granted: 2002-01-03
Abstract: This invention relates to the use of a eukaryotic or prokaryotic DNA-directed RNA polymerase of a class that synthesizes cellular RNA, in a process for the amplification of a specific nucleic acid sequence or of its complement. It also relates to a new process for amplifying a specific nucleic acid sequence. The process includes one or more reactions which may take place in a single reaction vessel. In one instance, in a first reaction, the process includes providing a first RNA polymerase which uses a DNA first template to synthesize an RNA first template, and, in a second reaction, providing the RNA first template and a number of other reagents such that the reagents use the RNA first template to synthesize a DNA second template and an RNA second template. Thereafter a cycle ensues in which the reagents use the RNA second template to synthesize a DNA third template and multiple copies of the RNA second template. The RNA second template is the specific nucleic acid sequence or its complement. This invention includes a kit containing the reagents of this invention.
Patent DE-69524409-D1 (DE)
Inventor: CREIGHTON PADRAIG MARIAN
IPC: E04F21/04
Filed: 1995-06-09
Granted: 2002-01-17
Abstract: A template (1) for use in forming a stucco pattern (5) on a wall (3) which comprises a plurality of grooves (9) comprises two pairs of spaced apart guide members (10) which are pivotally connected together by hinges (12), and the respective pairs of guide members (10) are connected by adjustable connecting members (14). Guide surfaces (16) on the guide member (10) form a guide opening (20) for accommodating the blade (51) of a trowel (2) for guiding the trowel (2) over a plaster layer (6) for forming the grooves (9). Working surfaces (17) of the trowel blade (51) slidably engage the guide surfaces (16) as the trowel (2) is being urged along the guide opening (20) for forming the grooves (9). Parts (24 and 25) of the template (1) may be pivoted about the hinges (12) relative to each other so that the parts (24 and 25) of the template (1) may be placed on surfaces of walls extending at an angle to each other.
Patent DE-69526356-D1 (DE)
Inventor: HEY-SHIPTON L
IPC: H01F17/00
Filed: 1995-08-22
Granted: 2002-05-16
Abstract: Thin film epitaxial high temperature superconductors are patterned to form lumped capacitors and inductors on low loss substrates. A ground plane (20), preferably of high temperature superconductive materials or high conductivity materials, such as gold or copper is placed on the substrate opposite to the patterned elements. Various structures such as a planar spiral conductor (24), or a zig-zag or serpentine conductor (42) can be formed. Additional structures such as narrow band reject filters (52) and bandpass filters can be formed. Chebyshev, elliptic and quasi-elliptic filters can be formed from a plurality of band-reject structures (116). Similarly, quasi-elliptical bandpass filters using a plurality of series connected bandpass structures with planar cross-couplings (134, 136, 138) can be formed. <IMAGE>
Patent DE-69530197-D1 (DE)
Inventor: HERRMANN DIETER
IPC: A61K31/7068
Filed: 1995-05-23
Granted: 2003-05-08
Abstract: The present invention is directed to new nucleoside monophosphate derivatives of lipid ester residues of general formula (I) <CHEM>     wherein   R<1>   may be a straight-chain or branched, saturated or unsaturated alkyl chain having 1-20 carbon atoms, R<2>   may be hydrogen, a straight-chain or branched, saturated or unsaturated alkyl chain having 1-20 carbon atoms, X   represents sulfur, a sulfinyl or sulfonyl group;and   Nucl. represents     2',3'-Didesoxy-2',3'-difluorothymidine     2'-Desoxy-2'-aminoadenosine     2'-Desoxy-2'-azidoadenosine     2'-Desoxy-2'-azidocytidine     2'-Desoxy-5-fluorouridine     2-Fluoro-2'-desoxyadenosine their tautomers and their physiologically acceptable salts of inorganic and organic acids and/or bases, as well as to processes for their preparation, and to drugs containing said compounds.
Patent DE-69531414-D1 (DE)
Inventor: DAVIS BRUCE
IPC: H04N7/16
Filed: 1995-10-27
Granted: 2003-09-04
Abstract: A method for determining whether one or more of a plurality of data fields for a plurality of television stations of a database that stores program schedule information for an electronic program guide contains missing or invalid data characterised by: 
allowing a user to select a station from the plurality of stations for verification of at least one of the data fields for the selected station; 
allowing the user to select a time range for the verification of the data fields; 
automatically analysing the data fields for the selected station for errors, wherein the errors are comprised of invalid or missing data; 
listing the detected errors; and 
providing the user with the ability to correct the detected errors.
Patent DE-69533072-D1 (DE)
Inventor: SANDERS FREDERICK
IPC: G01N33/58
Filed: 1995-06-23
Granted: 2004-06-24
Abstract: PCT No. PCT/GB95/01478 Sec. 371 Date May 30, 1997 Sec. 102(e) Date May 30, 1997 PCT Filed Jun. 23, 1995 PCT Pub. No. WO96/01428 PCT Pub. Date Jan. 18, 1996Labelling techniques for specific binding agents are provided wherein the label used comprises a microcapsule containing a nucleotide, preferably in solid form and preferably in crystalline form. Preferred nucleotide is ATP. The presence of labelled agent is determined by disrupting the microcapsule and measuring the amount of nucleotide so released; that being related to the amount of binding agent and thus any related interaction with the target for that agent such as a specific DNA or microorganism.
Patent DE-69535684-D1 (DE)
Inventor: ROTH JACK
IPC: A61K33/243
Filed: 1995-04-24
Granted: 2008-02-21
Abstract: Use of an effective combination of a p53 protein or gene and a DNA damaging agent for the preparation of a medicament for the treatment of cancer, wherein said p53 protein or gene is administered prior to or after said DNA damaging agent.
Patent DE-69635925-D1 (DE)
Inventor: BAR-SHAVIT RACHEL
IPC: C12Q1/6886
Filed: 1996-08-08
Granted: 2006-05-11
Abstract: The present invention concerns a method for evaluating the metastatic tendency of tumor cells by determining the level of expression (mRNA level) of the gene coding for the thrombin receptor (ThR) or by determining the level of the thrombin receptor present on the membranes or within the tumor cells. A high level of either of the above indicates a high metastatic tendency, a low level indicates a low metastatic tendency and an intermediate level indicates a moderate metastatic tendency. The present invention further concerns a kit for use in the above method.
Patent DE-69637734-D1 (DE)
Inventor: YU GUO-LIANG
IPC: C12N1/21
Filed: 1996-08-16
Granted: 2008-12-11
Abstract: The present invention concerns a novel member of the tumor necrosis factor (TNF) family of cytokines. In particular, isolated nucleic acid molecules are provided encoding the endokine alpha protein. Endokine alpha polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic and therapeutic methods concerning TNF family-related disorders.
Patent DE-69720326-D1 (DE)
Inventor: CULLINAN GEORGE JOSEPH
IPC: C07D333/56
Filed: 1997-06-25
Granted: 2003-05-08
Abstract: The instant invention provides novel benzothiophene compounds of the formula <CHEM>  wherein:   R1 is -H, -OH, -O(C1-C4 alkyl), -O-CO-(C1-C6 alkyl), -O-CO-O(C1-C6 alkyl), -O-CO-Ar in which Ar is optionally substituted phenyl, -O-CO-O-Ar in which Ar is optionally substituted phenyl, or -O-SO2-(C4-C6 alkyl); R2 is -H, -OH, -O(C1-C4 alkyl), -O-CO-(C1-C6 alkyl), -O-CO-O(C1-C6 alkyl), -O-CO-Ar in which Ar is optionally substituted phenyl, -O-CO-O-Ar in which Ar is optionally substituted phenyl, -O-SO2-(C4-C6 alkyl), -F, -Cl, or -Br;   n is an integer from 3 to 8; R3 and R4 each are independently C1-C4 alkyl, or combine to form, with the nitrogen to which they are attached, piperidinyl, pyrrolidinyl, methylpyrrolidinyl, dimethylpyrrolidinyl, or hexamethyleneimino; with the proviso that when n is 3, then neither R1 nor R2 can be -O-SO2-(C4-C6 alkyl); or a pharmaceutically acceptable salt or solvate thereof.
Patent DE-69724252-D1 (DE)
Inventor: HALL JOHN E JR
IPC: F24D17/00
Filed: 1997-04-12
Granted: 2003-09-25
Abstract: A water saving device for use with domestic hot water systems of the noncirculating storage tank heater type uses a hydraulic motor to drive a water pump to pump water from the hot water pipe to a cold water pipe. Pumping begins when a hot water tap connected to the device is turned on and the water in the hot water pipe is cold. Pumping continues until a temperature sensing element senses that hot water has reached the water saving device and actuates a valve. When hot water is present at the device, the valve permits the hot water to pass directly to the tap instead of driving the hydraulic motor.
Patent DE-69732027-D1 (DE)
Inventor: HACHIYA HIROSHI
IPC: C08J3/12
Filed: 1997-07-15
Granted: 2005-01-27
Abstract: Disclosed is a method for producing a polycarbonate pellet, which comprises subjecting a melt-extruded polycarbonate to cooling and cutting in this or reverse order or simultaneously, wherein the cooling is performed using cooling water having an electric conductivity of 1 mS/cm or less as measured at 25  DEG C, and is also concerned with a polycarbonate improved with respect to the suppression of occurrence of crazing which can be obtained by the above-mentioned method. From the polycarbonate pellet obtained by the present invention, a molded polycarbonate product can be obtained which is improved with respect to the suppression of occurrence of crazing even when the product has experienced moist heat environment conditions. Therefore, the polycarbonate pellet of the present invention can be advantageously used for the production of a molded polycarbonate product which is suitable for use in fields (such as the medical field and food-related field) in which a molded polycarbonate product is repeatedly subjected to sterilization by means of hot water or steam, and an optical field (such as an optical disc) in which an optical defect caused by the occurrence of crazing in a molded polycarbonate product is a serious problem.
Patent DE-69737916-D1 (DE)
Inventor: KNUDSEN LISELOTTE BJERRE
IPC: A61P3/04
Filed: 1997-11-07
Granted: 2007-08-23
Abstract: GLP-1(1-45) or a fragment or an analogue thereof can be used in the preparation of a medicament for peripheral administration in the suppression of appetite or induction of satiety.
Patent DE-69738155-D1 (DE)
Inventor: GROB MATTHEW S
IPC: H04B7/005
Filed: 1997-06-06
Granted: 2007-10-31
Abstract: In a dispatch system, power of the forward link broadcast channel transmitted from a base station is controlled such that the power level is the minimum necessary and such that transmission of the forward link broadcast channel is terminated if no remote unit is located within the coverage area of the base station. In addition to transmitting a forward link broadcast signal, the base station monitors an access channel. A first remote unit in the base station coverage area receives and decodes the forward link broadcast signal. The first remote unit determines a signal quality of said forward link broadcast signal. If the signal quality is unacceptable, the remote unit transmits a power request access message. The base station responds to the request by increasing the transmission power of forward link broadcast channel. If no requests are received at the base station, the forward link broadcast channel is slowly decreased to a minimum. Transmission of the forward link broadcast channel may be terminated completely.