baber/WOPTO huggingface dataset:
Patent NZ-596487-A (NZ)
Title: 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES AND THE USE THEREOF AS PI3K INHIBITORS
Inventor: FURET PASCAL
IPC: A61K31/437
Filed: 2010-06-02
Abstract: Disclosed herein are compounds of formula (I), wherein X is O or S; Y is CH or N; R1 is a substituted or unsubstituted 5-membered heteroaryl; R2 is hydrogen,C1-C4 alkyl or C1-C4 alkenyl; R3 is a substituted or unsubstituted aryl or heterocyc!yl; and R4, R5 and R6 are hydrogen; and the use thereof in the treatment of a lipid and/or protein kinase dependent disease, such as proliferative disease, a benign or malignant tumor, a carcinoma of the brain, kidney, liver, adrenal gland, bladder, breast, stomach, gastric tumors; ovaries, colon, rectum, prostate, pancreas, lung, vagina or thyroid, sarcoma, glioblastomas, multiple myeloma or gastrointestinal cancer, colon carcinoma or colorectal adenoma or a tumor of the neck or head, an epidermal hyperproliferation, psoriasis, prostate hyperplasia, a neoplasia, a neoplasia of epithelial character, lymphomas, a mammary carcinoma or a leukemia, Cowden syndrome, Lhermitte-Dudos disease or Bannayan~Zonana syndrome, basal cell carcinoma, squamous cell carcinoma, actinic keratosis, a benign hyperproliferative skin disorder caused by inflammation, such as psoriasis or as a result of dysregulation of fibroblasts such as skin fibrosis, scleroderma or keloids, Exemplary compounds include: 8-(3,4-dimethoxy-phenyl)-1-(1,5-dimethyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one; 1-(2-ethyl-2H-pyrazol-3-yl)-8-(6-methoxy-pyridin-3-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one; and 5-[1-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyI-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl]-2-methoxy-N-methyl-nicotinamide.
Patent NZ-599774-A (NZ)
Title: Melanocortin-1 receptor-specific cyclic peptides
Inventor: YANG WEI
IPC: C07K7/50
Filed: 2010-11-23
Abstract: The disclosure relates to cyclic peptides of formula (VII), where the peptides are as defined in the specification. Xaa2 and Xaa6 are connected via a cyclic bridge. The peptides have use for preventing, ameliorating or treating melanocortin-1 receptor-mediated or responsive diseases, indications, conditions and syndromes. Specific peptides include: Ac-Nle-cyclo(Glu-His-D-Phe-Arg-Dab)-Trp-NH2 Ac-Nle-cyclo(Glu-His-D-Phe-Arg-Dap)-Trp-NH2
Patent NZ-600480-A (NZ)
Title: Flow generator message system
Inventor: OATES JOHN DAVID
IPC: A61M16/00
Filed: 2006-10-13
Abstract: 600480 A flow generator (10) for use with a continuous positive airway pressure (CPAP) system or a non-invasive positive pressure ventilation (NIPPV) system configured to supply breathable gas to a patient at a pressure elevated above atmospheric pressure, the flow generator comprising: a motor configured to generate the supply of breathable gas to a patient; at least one operation sensor (34) to generate signals; and a processor (18) coupled to the at least one operation sensor. The processor is configured to determine at least one identifying feature of a peripheral component that is coupled to the flow generator; discern the specific peripheral component based on the determined at least one identifying feature; and generate at least one message that relates to at least one of flow generator operation, flow generator service, flow generator use, patient health, peripheral devices and services, and patient treatment based on the discerned specific peripheral component.
Patent NZ-609524-A (NZ)
Title: Devices and systems for absorbing impacts
Inventor: DURUZ PAUL EDWARD
IPC: F16F7/00
Filed: 2007-05-10
Abstract: A C shaped barrier for protection of refrigeration walls from impact has a top part 210 at an acute inclined angle to an upright portion 190 for determining energy absorption due to twisting motion caused by selection of a particular included angle
Patent NZ-614063-A (NZ)
Title: Blower and pap system
Inventor: MOIR MICHAEL BRUCE
IPC: F04D29/66
Filed: 2012-02-22
Abstract: A wearable PAP system comprising a blower (510). The blower (510) includes a housing including an inlet and an outlet, a stationary component provided within the housing, an impeller positioned between the inlet of the housing and the stationary component, and a motor adapted to drive the impeller. The stationary component includes a tube portion structured to retain and align a pair of bearings (552, 554) that rotatably support a shaft (550), or rotor, to which the impeller is coupled. The tube portion includes a diameter in a side closest to the impeller that is sufficient size to accommodate adhesive to retain one of the bearings. The shaft (550) comprises a groove (551) that acts to reduce the stiffness of the shaft to attenuate mechanical resonances, lower the magnitude of imbalance, and/or reduce bearing frequency peaks in use. The diameter of the groove may be between 50% and 95% of the shaft outer diameter, and the width of the groove may be between 20% and 50% of the shaft outer diameter. Smaller grooves (not shown) may extend along the length of the shaft, particularly in a double helix configuration.
Patent NZ-614082-A (NZ)
Title: Pyrrolotriazinone derivatives as pi3k inhibitors
Inventor: BERNAL ANCHUELA FRANCISCO JAVIER
IPC: C07D487/04
Filed: 2012-04-26
Abstract: New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks). In one embodiment the derivative is (S)-2-(1-(9H-purin-6-ylamino)propyl)-3-phenylpyrrolo[1,2-f][1,2,4]triazin-4(3H)-one.
Patent NZ-622485-A (NZ)
Title: Shared cache used to provide zero copy memory mapped database
Inventor: NIMA GHAMSARI
IPC: G06F17/30
Filed: 2014-03-14
Abstract: Disclosed is a method for providing a plurality of applications with concurrent access to data in a cache. The method includes identifying a plurality of attributes of an expected data set to be accessed concurrently by the plurality of applications and allocating a memory space for a shared cache. The shared cache comprises a column data store configured to store data for each of the plurality of attributes of the expected data set in columns. The method also includes retrieving the expected data set from a database and populating the shared cache with the expected data set. The method further includes storing memory address locations corresponding to the columns of the column data store of the shared cache for access by the plurality of applications. Each application generates a memory map from memory locations in a virtual address space of each respective application to the stored address memory locations.
Patent NZ-711283-A (NZ)
Title: Compositions and methods for lowering triglycerides without raising ldl-c levels
Inventor: MANKU MEHAR
IPC: C12P7/64
Filed: 2010-06-15
Abstract: Disclosed is the use of ethyl eicosapentaenoate (EPA) in the manufacture of a medicament for preventing myocardial infarction and/or stroke in a subject on stable statin therapy, wherein: (a) the subject has previously been identified as having dyslipidemia, as being on stable statin therapy and as having a fasting baseline triglyceride level of about 200 mg/dL to about 500 mg/dL, optionally wherein said subject has established cardiovascular disease or has a high risk of developing cardiovascular disease; and (b) the medicament is formulated for daily administration to provide about 4 g of the ethyl eicosapentaenoate per day.
Patent NZ-714339-A (NZ)
Title: Door-frame hook for securing vehicle roof-top loads
Inventor: BUCHMAN YOSEF
IPC: B60R9/058
Filed: 2014-04-22
Abstract: There is disclosed a door-frame hook, for enabling a load strap, attached to a roof-top load carrier, on a vehicle, to engage a door frame of the vehicle so as to secure the load carrier onto the vehicle when the load strap is tightened, said hook being configured so that it may be anchored onto a frame ridge of said door frame and thereafter be, in part, covered by a sealer attached to said door frame and further configured so that said load strap may be attached thereto. The door-frame hook of the invention may, advantageously, remain in position, between the frame-ridge of the door frame and the sealer potter, regardless of the degree of tightness of the load strap or the degree of its pull on the hook, as well as when the load strap is unattached. Moreover, it does not harm the door sealer nor does it interfere in any way with its sealing function or with the shutting action of the door.
Patent NZ-715433-A (NZ)
Title: Sealing disk for a closure cap for containers, especially bottles
Inventor: KRÖGER RAINER
IPC: C12H1/056
Filed: 2014-07-01
Abstract: A sealing disc for a closure cap for a container having a closure cap for engagement with a neck of the container the container typically including a liquid fermented with yeast. The sealing disc includes a layered structure that is arranged in a sequence from a top layer to the lowest layer, said lowest layer being in use in contact with the opening of the container. The layered structure is comprised of multiple layers all of the same diameter and is comprised of: a top layer of a polymer foamed material arranged for contact at the closure cap; an active layer and a plastic foil; said active layer being applied to or worked into the plastic foil. The plastic foil is made from a polymer selected from ethylene homopolymers, linear copolymers of ethylene with one or more of α-olefines comprising 3 to 14 carbon atoms, polypropylene, unstretched polypropylene, oriented polypropylene, polyamide, oriented polyamide and polyethylene terephthalate and forms the lowest layer of the layered structure. The active layer includes an active substance which binds sulfur compounds, and the active substance is selected from copper, silver, gold, antimony, alloys thereof, salts thereof including oxides and hydroxides which react with the sulfur compounds.
Patent NZ-721204-A (NZ)
Title: System and method for object tracking anti-jitter filtering
Inventor: EVANSEN EDWARD G
IPC: G06T19/20
Filed: 2013-11-12
Abstract: Object tracking anti-jitter filtering systems and methods. A plurality of raw location points for a tracking tag attached to a tracked object is received. The raw location points are stored within a raw location points buffer. Raw location points within an averaging window are averaged to generate an averaged location point. The averaged location point is stored within an averaged location points buffer for use within the object tracking system. The duration of the averaging period is dynamically adjusted to include a desired number of the raw location points within the averaging period.
Patent NZ-722231-A (NZ)
Title: Interrogatory cell-based assays for identifying drug-induced toxicity markers
Inventor: SARANGARAJAN RANGAPRASAD
IPC: G01N33/53
Filed: 2012-09-07
Abstract: The instant application provides methods for identifying modulators of drug-induced toxicity by identifying, from a consensus causal relationship network generated by an artificial intelligence (AI) -based informatics platform, a causal relationship unique in drug-induced toxicity, wherein a gene, lipid, protein, metabolite, transcript, or SNP associated with the unique causal relationship is identified as a modulator of drug-induced toxicity.
Patent NZ-732808-A (NZ)
Title: Systems, devices and methods for dispensing oral transmucosal dosage forms
Inventor: CHIU EDMOND
IPC: A61J3/10
Filed: 2015-12-22
Abstract: An apparatus, comprising: a housing defining a passage and an exit port in fluid communication with the passage; an actuator hub rotatably disposed within a hub volume defined by the housing; and a pushrod coupled to the actuator hub and having a proximal end portion and a distal end portion, the distal end portion of the pushrod movable from a first position within the passage to a second position to move a drug dosage form through at least a portion of the passage to convey the drug dosage form through the exit port, a portion of the pushrod including the proximal end portion being wound about the actuator hub when the distal end portion of the pushrod is in the first position, the proximal end portion of the pushrod having a prefabricated bend of less than 180 degrees that dampens a deformation force produced during rotation of the actuator hub to move the distal end portion of the pushrod from the first position to the second position, a surface of at least one of the pushrod or the housing defining the passage having a contact reducing surface profile configured to substantially prevent negative acceleration of the distal end portion of the pushrod within the passage from the first position to the second position.
Patent NZ-733351-A (NZ)
Title: Combinations of modalities for the treatment of diabetes
Inventor: ORBAN TIHAMER
IPC: A61P3/10
Filed: 2013-06-27
Abstract: A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus by administering an effective amount of a fusion protein composition comprising a T-cell co-stimulation antagonist and a portion of an immunoglobulin molecule and an effective amount of a Type 1 diabetes autoantigen. The method includes, for example, administering a cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) molecule and a B-chain insulin vaccine. Pharmaceutical compositions are also provided herewith.
Patent NZ-739866-A (NZ)
Title: A bale wrapping apparatus and a method for wrapping a bale made from a crop product
Inventor: BAKER TIM
IPC: A01F15/07
Filed: 2016-07-28
Abstract: The application discloses a bale wrapping apparatus (100), comprising a wrapping table with bale rotating means (112, 122) to hold, control and rotate a bale for the application of a wrapping material, and dispenser means (300) configured to dispense the wrapping material from rolls, and a dispenser means rotational support (116) configured to rotate the dispensed wrapping material around a uniform and/or non-uniform bale of material around a central rotating axis, and a wrapping control system configured to power, control, adjust and/or regulate the dispensed wrapping material through the dispenser means (300) to a predefined stretch ratio within acceleration and/or deceleration zones within one or more 360 degree rotations of the dispenser means rotational support (116). Furthermore, the application discloses a method for wrapping a bale (200) made from a crop product by a bale wrapping apparatus (100).
Patent NZ-755863-A (NZ)
Title: Cushion for Patient Interface
Inventor: HITCHCOCK ROBIN GARTH
IPC: A61M16/06
Filed: 2006-01-12
Abstract: A cushion (10) for a patient interface that delivers breathable gas to a patient, the cushion including a nasal bridge region (16), a pair of side of nose regions (17), a pair of upper cheek regions (18), a pair of lower cheek regions (19) and a chin region (20). The cushion includes a base wall (28) and a membrane (32, Fig 8) connected to the base wall. The membrane has a thickness and includes a nasal bridge region, a pair of side of nose regions, a pair of upper cheek regions, a pair of lower cheek regions and a chin region adapted to form a continuous seal, respectively, on a nasal bridge region, a pair of side of nose regions, a pair of upper cheek regions, a pair of lower cheek regions and a chin region of a patient’s face. The thickness of the membrane in at least one of the nasal bridge region, the pair of side of nose regions, the pair of upper cheek regions, the pair of lower cheek regions and the chin region is different than the thickness in at least one other region. An exterior surface of the membrane in the nasal bridge region forms an elongated ridge having sloping sides that meet to form an elongated crest. The exterior surface of the membrane in the chin region extends from one lower cheek region to the other lower cheek region and forms a concave shape adapted to engage the patient’s chin region. The membrane in the nasal bridge region is configured to invert, in use, with a rolling edge to accommodate patients having a range of nasal bridge profiles.
Patent NZ-760296-A (NZ)
Title: Inter-penetrating elastomer network derived from ground tire rubber particles
Inventor: COE WILLIAM
IPC: C08K9/10
Filed: 2018-08-02
Abstract: A polymeric matrix comprises a crosslinked network of end-of-life tire derived rubber and at least one complementary polymer. The polymeric matrix encapsulates nano-carbon clusters comprising carbon black and/or graphene particles in a film of interfused asphalt molecules. The nano-carbon clusters are adapted to shield and/or stabilize the asphalt molecules from energy of polariton discharges generated at energy transfer regions.
Patent PT-103374-A (PT)
Inventor: SEQUEIRA ABREU ANTONIO MANUEL
IPC: A61N1/40
Filed: 2005-10-28
Abstract: The present invention refers to a device used to recharge the battery of electronic cardiac implants, like implanted pacemakers and defibrillators. It can be used to recharge the battery after an emergency requirement, such as: defibrillation or in diagnosis and or reprogramming of implants, during which no energy is demanded from the internal battery, seeing that the energy feed becomes guaranteed (accepted) by the proposed device. The invention is composed by three essential components: a generator (A), a transmitter unit (B) and a receptor coil (C). The generator is destined to produce an energy signal with determined amplitude and frequency and that is carried across through a coaxial cable to the transmitter unit (B). The emitted magnetic field is captured by the receptor coil (C) that is implanted inside the human body, generating a voltage with the absence of the Gibbs phenomenon. Furthermore, the battery recharging device guarantees the energetic supply of a communication channel between the exterior for diagnosis and/or implant reprogramming. In this case, there will be no demand of energy from the internal battery.
Patent PT-104071-A (PT)
Title: Baterias constituidas por ânodo de alumínio, usando liquido iónico como electrólito e com possibilidade de recarga
Inventor: CORREIA PEDRO BRITO
IPC: H01M4/50
Filed: 2008-05-26
Abstract: SÃO CONHECIDAS AS BATERIAS COM ÂNODO DE ALUMÍNIO USANDO ELECTRÓLITOS AQUOSOS, SEM POSSIBILIDADE DE RECARGA. SÃO TAMBEM CONHECIDAS BATERIAS QUE USAM LÍQUIDOS IÓNICOS COMO ELECTRÓLITO, MAS NÃO USAM ALUMÍNIO COMO ÂNODO. APRESENTAMOS UMA NOVA BATERIA QUE SE BASEIA NA UTILIZAÇÃO DUM ÂNODO DE ALUMÍNIO EM QUE OS ÁTOMOS DE ALUMÍNIO PASSAM DUMA FORMA REVERSÍVEL AO IÃO A13+, USANDO COMO ELECTRÓLITO UM LIQUIDO IÓNICO, E COMO CÁTODO DIFERENTES MATERIAIS COMO POR EXEMPLO COMPOSTOS DE MANGANÊS. A DIFICULDADE EM RECARREGAR ANTERIORES BATERIAS DE ALUMÍNIO RESULTAVA DO FACTO DO ELECTRÓLITO SER AQUOSO, O QUE LEVAVA Á FORMAÇÃO DE A1203, QUE PELA SUA ESTABILIDADE IMPEDIA A REVERSIBILIDADE DA PASSAGEM DE A13+ A ALUMÍNIO METÁLICO. A INTRODUÇÃO DE LÍQUIDOS IÓNICOS COMO ELECTRÓLITOS TORNA A BATERIA DE ALUMÍNIO RECARREGÁVEL. ESTAS BATERIAS TEM UM INTERESSE MUITO GRANDE PARA A SUBSTITUIÇÃO NOS MEIOS DE TRANSPORTE, DE COMBUSTÍVEIS FOSSEIS POR ENERGIA ELÉCTRICA. DE FACTO, AS BATERIAS RECARREGÁVEIS DE ÂNODO DE ALUMÍNIO PERMITEM DUMA FORMA BARATA ACUMULAR REVERSIVELMENTE UMA GRANDE CARGA ELÉCTRICA EM POUCO PESO E VOLUME.
Patent PT-105569-A (PT)
Title: Madre modular multifuncional
Inventor: MATOS SERGIO FRANCISCO DA SILVA
IPC: E04G11/52
Filed: 2011-03-16
Abstract: MADRE MODULAR MULTIFUNCIONAL CONSTRUÍDA EM AÇO ESTRUTURAL OU MATERIAL LEVE E RESISTENTE EQUIVALENTE, COM CONFIGURAÇÃO EM "U", É DOTADA DE FURAÇÕES AO LONGO DE TODO O SEU COMPRIMENTO, QUER NO DORSO (1 E 1-A), QUER NAS ILHARGAS (2 E 2-A), QUER NAS ABAS (3 E 3-A), ACOPLANDO AS DITAS MADRES UMAS NAS OUTRAS, ATRAVÉS DO DORSO, ILHARGAS OU ABAS, EM QUALQUER ÂNGULO, SENDO A FIXAÇÃO EFECTUADA ATRAVÉS DE PARAFUSOS INTRODUZIDOS NAS DITAS FURAÇÕES E DISPENSANDO QUALQUER SOLDADURA. AS ILHARGAS E AS ABAS POSSUEM QUINAGENS (2-B E 3-B), ADEQUADAS A FACILITAR O ENCAIXE E FIXAÇÃO DE MADRES. A MADRE PODE ACOPLAR POR SOBREPOSIÇÃO DO DORSO, POR UNIÃO DAS ABAS, POR UNIÃO DE ILHARGAS, POR UNIÃO DE ILHARGAS COM ABAS, ABAS OU ILHARGAS COM DORSO, PERMITINDO ACOPLAGEM DIRECTA OU INVERTIDA E TEM A FUNCIONALIDADE DE ASSUMIR, CONFORME SE DESEJE, O PAPEL DE VIGA, PILAR, TIRANTE OU TRAVE, SENDO ESPECIALMENTE INDICADA NA CONSTRUÇÃO DE VÃOS DE GRANDE DIMENSÃO EM PAVILHÕES OU CONSTRUÇÕES SIMILARES.
Patent PT-116961-A (PT)
Title: Modelo dinâmico de digestão gástrica e programa de computador
Inventor: ANA CRISTINA BRAGA PINHEIRO
IPC: G09B23/30
Filed: 2020-12-21
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A UM MODELO GÁSTRICO MODULAR IN VITRO COM NATUREZA DINÂMICA E ANÁLISE IN SITU, PARA MONITORIZAÇÃO EM TEMPO REAL DO PROCESSO DE DIGESTÃO DE ALIMENTOS, SISTEMAS DE LIBERTAÇÃO CONTROLADA, COMPOSTOS BIOATIVOS E FÁRMACOS. ESTE MODELO COMPREENDE PELO MENOS 7 MÓDULOS CAPAZES DE REPLICAR AS CONDIÇÕES FÍSICO-QUÍMICAS QUE OCORREM AO LONGO DA DIGESTÃO NO ESTÔMAGO HUMANO. A ENTRADA DO ESTÔMAGO ARTIFICIAL (4) PERMITE A ADIÇÃO DAS AMOSTRAS DE ALIMENTOS OU FÁRMACOS, ASSIM COMO DAS SOLUÇÕES ELETROLÍTICAS E ENZIMÁTICAS. APÓS DIGESTÃO DAS AMOSTRAS POR AÇÃO DO PADRÃO DE BANDAS PERISTÁLTICAS (8), ESTAS SÃO ENCAMINHADAS PELA SAÍDA (7) PARA POSTERIOR ANÁLISE NA CÂMARA DE ANÁLISE (18), COMPOSTA PELO SENSOR DE NÍVEL (17) E ESTRUTURA DE SUPORTE DA SONDA DE FIBRA ÓTICA (16), E POSTERIORMENTE, ELIMINADAS PELA SAÍDA DO SISTEMA (21 E 30). ESTE MODELO DE DIGESTÃO PERMITE ASSIM REDUZIR O ESFORÇO E TEMPO DE ANÁLISE E CUSTOS ASSOCIADOS.
Patent RU-94026545-A (RU)
Inventor: SHAMSIEV B G
IPC: H02M5/44
Filed: 1994-07-18
Abstract: FIELD: electric engineering, electric power supply of electronic devices and computers during mains voltage falls. SUBSTANCE: device has charge rectifier 1, which output is connected to redundant power supply 2 and high-frequency inverter 3, which control input is connected through commutator 4 to control unit 5, which sends modulating voltage, for example, by means of pulse series. During single half-period commutator 4 switches supply of modulating voltage between diagonals of bridge of high-frequency inverter 3, which outputs amplified double-polarity series of pulses. Said series is rectified by high-frequency rectifier 6 and is converted to single-polarity pulse voltage by means of smoothing filter 7. This voltage is supplied to input of low-frequency inverter 8, which switching is controlled by control unit 5. This results in output of sine-shaped voltage of 220 V and 50 Hz from low-frequency inverter 8. EFFECT: increased stabilization range, decreased size. 3 cl, 1 dwg
Patent RU-94030294-A (RU)
Inventor: DEMIN S B
IPC: G01F23/28
Filed: 1994-08-16
Abstract: FIELD: instrumentation engineering. SUBSTANCE: invention is aimed at check and measurement of levels of liquid and loose materials under special conditions. Ultrasound level gauge has magnetostrictive acoustic line 3 lowered into tank 1 with checked medium 2, acoustic absorber 4, reflectors 5,6, float with polarizer 7, generator 9 of recording pulses, selective reading amplifier 10, computation unit 11 and output wires 12, 13, 14. EFFECT: increased authenticity and precision of measurements of level, expanded application field, decreased influence of destabilization factors and simplified design. 1 cl, 3 dwg