baber/WOPTO huggingface dataset:
Patent NZ-589289-A (NZ)
Title: Polymer microgel beads and preparative method thereof
Inventor: HAWKETT BRIAN STANLEY
IPC: A61K41/00
Filed: 2009-05-15
Abstract: Disclosed are polymer microgel beads (a) having a polymeric matrix that can absorb and be swollen by an aqueous liquid, and (b) incorporating nanomagnetic particles, wherein a steric stabiliser is associated with the particles which are distributed substantially uniformly throughout the polymeric matrix, the steric stabiliser being a polymeric material that (i) forms at least part of the polymeric matrix of the beads, and (ii) comprises a steric stabilising polymeric segment and an anchoring polymeric segment, wherein the steric stabilising polymeric segment is different from the anchoring polymeric segment, and wherein the anchoring polymeric segment has an affinity. Also disclosed is a method for the preparation of the polymer microgel beads comprising providing a dispersion comprising (i) providing a dispersion comprising a continuous organic phase and a dispersed aqueous phase, the dispersed aqueous phase comprising hydrophilic liquid and nanomagnetic particles dispersed throughout the aqueous phase, the nanomagnetic particles being maintained in their dispersed state by a steric stabiliser, wherein the steric stabiliser is a polymeric material comprising: a) a steric stabilising polymeric segment and an anchoring polymeric segment, wherein the steric stabilising polymeric segment is different from the anchoring polymeric segment, and wherein the anchoring polymeric segment has an affinity toward the nanomagnetic particles and binds the steric stabiliser to the particles; and b) one or more reactive functional group; (ii) removing hydrophilic liquid from the aqueous phase; and (iii) promoting a reaction between the reactive functional groups of the steric stabilisers to thereby form the polymer microgel beads incorporating the nanomagnetic particles. The microgel beads are useful in hyperthermia treatments of tissue such as cancerous tissue. The beads are administered to a subject and exposed to a magnetic field, causing the beads to radiate heat at a target site.
Patent NZ-595986-A (NZ)
Title: A novel formulation of indomethacin
Inventor: DODD AARON
IPC: A61K31/405
Filed: 2010-04-23
Abstract: 595986 The present specification relates to methods for producing particles of indomethacin by dry milling indomethacin, a facilitating agent and a millable grinding matrix in a mill comprising a plurality of milling bodies. Also, compositions comprising indomethacin, medicaments produced using indomethacin in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of indomethacin administered by way of said medicaments are disclosed. Said particles having an average particle size is equal to or less than 2000nm and wherein the total combined amount of biologically active material and grinding matrix in the mill at any given time is selected from the group consisting of: 200 grams, 500 grams, 1 kg, 2kg, 5 kg, 10 kg, 20 kg, 30 kg, 50 kg, 75 kg, 100 kg, 150 kg, 200 kg, 500 kg, 1000 kg, 1500kg and 2000 kg. Exemplary compositions include compositions comprising milling matrices and facilitating agents such as the following together with indomethacin: sodium lauryl sulfate, tartaric acid, lactose, talc, kaolin, microcrystalline cellulose, xylitol, sodium chloride, glucose, sucrose and mannitol.
Patent NZ-596459-A (NZ)
Title: Phytases, nucleic acids encoding them and methods for making and using them
Inventor: WEINER DAVID P
IPC: C07H21/04
Filed: 2010-05-20
Abstract: 596459 Disclosed is an isolated, synthetic, or recombinant nucleic acid or amino acid sequence encoding a polypeptide having phytase activity wherein the polypeptide has at least one amino acid mutation from the sequence defined herein that improves the gastric lability of the polypeptide having phytase activity. SEQ ID NO: 2MKAILIPFLSLLIPLTPQSAFAQSEPELKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGELTPRGGELIAYLGHYWRQRLVADGLLPKCGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILERAGGSIADFTGHYQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPSELKVSADCVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFDLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL
Patent NZ-597575-A (NZ)
Title: Medical light source that flexibly conforms to non planar or curved surface on a patients body
Inventor: MCNEILL ANDREW
IPC: A61N5/06
Filed: 2010-04-29
Abstract: 597575 Disclosed is an apparatus for use in therapeutic and/or cosmetic treatment using light or phototherapy or conjunction with a medicament in photodynamic therapy to allow more effective treatment through improved contact with a patient's skin. The apparatus comprises a casing with electronics located within or attached to the casing and at least one light source. A chassis is located within the casing wherein along at least part of or substantially the whole length of the chassis there are channels on at least one or both sides of the chassis which supports a flexible electronic substrate. A protruding member in the chassis of the casing functions as a runner for the flexible electronic substrate. The casing includes a series of hinges which allow the apparatus to bend so as to adapt to and/or conform to a non-planar surface. The channels support the flexible electronic substrate and allowing the flexible electronic substrate to be free or substantially free to move along the channels. The chassis consists of an upper chassis and a lower chassis and the channels allow the upper chassis and the lower chassis to bend in tandem or substantially in tandem with the flexible electronic substrate being free or substantially free to move along the channels during bending and/or flexing.
Patent NZ-597655-A (NZ)
Title: Method for predicting efficacy of drugs in a patient
Inventor: LAZAR VLADIMIR
IPC: G16H10/60
Filed: 2010-07-06
Abstract: Disclosed is a method for predicting the relative efficacy of a plurality of drugs for treating a cancer in a patient comprising: - characterizing molecular anomalies of a tumour sample from the patient in comparison to a normal sample from the same patient, thereby determining the deregulated genes in the tumour; - providing a database comprising the target genes for each drug of the plurality of drugs; - determining a score for each drug of the plurality of drugs essentially based on the percentage of deregulated genes among the target genes for each drug in the tumour sample from the patient, thereby a higher score is predictive of a higher relative efficacy of the drug for treating the tumour in the patient.
Patent NZ-597912-A (NZ)
Title: Pegylated l-asparaginase
Inventor: ABRIBAT THIERRY
IPC: A61K47/48
Filed: 2010-07-06
Abstract: Patent No. 597912 Disclosed is a conjugate comprising an L-asparaginase from Erwinia having at least 80% identity to the amino acid sequence: ADKLPNIVILATGGTIAGSAATGTQTTGYKAGALGVDTLINAVPEVKKLANVKGEQFSNMASENMTGDVVLKLSQRVNELLARDDVDGVVITHGTDTVEESAYFLHLTVKSDKPVVFVAAMRPATAISADGPMNLLEAVRVAGDKQSRGRGVMVVLNDRIGSARYITKTNASTLDTFKANEEGYLGVIIGNRIYYQNRIDKLHTTRSVFDVRGLTSLPKVDILYGYQDDPEYLYDAAIQHGVKGIVYAGMGAGSVSVRGIAGMRKAMEKGVVVIRSTRTGNGIVPPDEELPGLVSDSLNPAHARILLMLALTRTSDPKVIQEYFHTY and polyethylene glycol (PEG), wherein the PEG has a molecular weight less than or equal to about 5000 Da.
Patent NZ-598403-A (NZ)
Title: Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
Inventor: MAIYURAN SUCHINDRA
IPC: C12N1/15
Filed: 2008-12-18
Abstract: An isolated polypeptide having cellulolytic enhancing activity, selected from the group consisting of: (a) a polypeptide comprising an amino acid sequence having at least 85% identity to the mature polypeptide of SEQ ID NO: 4; (b) a polypeptide encoded by a polynucleotide that hybridizes under at least very high stringency conditions with (i) the mature polypeptide coding sequence of SEQ ID NO: 3 (ii) the cDNA sequence contained in the mature polypeptide coding sequence of SEQ 10 NO: 3 or (iii) a full-length complementary strand of (i) or (ii); (c) a polypeptide encoded by a polynucleotide comprising a nucleotide sequence having at least 85% identity to the mature polypeptide coding sequence of SEQ ID NO: 3; and (d) a variant comprising a substitution, deletion, and/or insertion of one or more amino acids of the mature polypeptide of SEQ ID NO: 4.
Patent NZ-598929-A (NZ)
Title: Dual variable domain immunoglobulins and uses thereof
Inventor: GHAYUR TARIQ
IPC: C07H21/00
Filed: 2010-09-01
Abstract: Disclosed is a binding protein comprising first and second polypeptide chains, each independently comprising VD1-(X1)n-VD2-C-(X2)n, wherein: VD1 is a first variable domain; VD2 is a second variable domain; C is a constant domain; X1 is a linker; X2 is an Fc region; and n is 0 or 1; wherein the VD1 domains on the first and second polypeptide chains form a first functional target binding site and the VD2 domains on the first and second polypeptide chains form a second functional target binding site, and wherein the binding protein is capable of binding: (a) methotrexate (MTX) and CD3, wherein the variable domains that form a functional target binding site for MTX and the variable domains that form a functional target binding site for CD3 are as defined in the complete specification; (b) MTX and EGFR, wherein the variable domains that form a functional target binding site for MTX and the variable domains that form a functional target binding site for EGFR are as defined in the complete specification; (c) MTX and HER-2, wherein the variable domains that form a functional target binding site for MTX and the variable domains that form a functional target binding site for HER-2 are as defined in the complete specification; (d) MTX and CD-19, wherein the variable domains that form a functional target binding site for MTX and the variable domains that form a functional target binding site for CD-19 are as defined in the complete specification; or (e) MTX and CD-20, wherein the variable domains that form a functional target binding site for MTX and the variable domains that form a functional target binding site for CD-20 are as defined in the complete specification.
Patent NZ-601393-A (NZ)
Title: Retraction and distraction assemblies
Inventor: SEEX KEVIN
IPC: A61B17/02
Filed: 2012-07-23
Abstract: 601393 An assembly for use in a surgical procedure, including a frame capable of bone distraction and which receives and retains retraction arms for retraction of soft tissue during the surgical procedure; the frame including a first member including a recess which receives a first bone anchor and a second member which co-operates with the first member and receives a second bone anchor; the first member including at least one retaining arm which receives thereon a retractor arm; wherein, the second member is adjustable relative to the first member to allow distraction of bones to which the first and second bone anchors are attached.
Patent NZ-603317-A (NZ)
Title: An adaptive light sensitive switch which includes a processor and sensor for detecting ambient light level value
Inventor: FRASER STEVEN
IPC: F21S8/00
Filed: 2012-10-30
Abstract: Disclosed is an adaptive light sensitive switch. The switch includes a sensor for detecting an ambient light level value, a processor configured to communicate with the sensor and a memory for storing a computer executable computer program. The computer program is configured to direct the processor to adaptively switch a light on and off during a current night. The program includes computer executable software code for storing information based on the output of the sensor and determining, based upon said stored information, a duration of at least one calibration night, said at least one calibration night being prior to the current night. The program also includes code for estimating, based upon the duration of the at least one calibration night, a duration of the current night and switching the light on at or near a sunset time immediately preceding the current night, for a first proportion of said duration of the current night; subsequently switching the light off for a second proportion of said duration of the current night; and subsequently switching the light on for a remainder of the duration of the current night until at or near a sunrise time immediately following the current night.
Patent NZ-605799-A (NZ)
Title: Wdrpuh epitope peptides and vaccines containing the same
Inventor: TSUNODA TAKUYA
IPC: C12N15/09
Filed: 2009-12-03
Abstract: 605799 Disclosed is an isolated peptide of less than 15 amino acids, capable of binding to an HLA antigen which comprises an amino acid selected from sequences such as QLQGGITSI, KLLTDVGPA, SLSGSINGM, KVWDYNEGEV and so on.
Patent NZ-608406-A (NZ)
Title: Use of storage stable viscous phospholipid depot to treat wounds
Inventor: CHEN HAILIANG
IPC: A61P17/02
Filed: 2011-10-18
Abstract: Disclosed is a clear depot comprising a hydrophilic water-soluble pharmaceutically active agent(s) selected from the group consisting of a pharmaceutically acceptable salt of vancomycin, gentamicin, and a mixture thereof, water, a phospholipid, an oil, a pH adjusting agent, and a viscosity modifying agent selected from the group consisting of ethanol, isopropanol, and a mixture thereof, wherein the water present in the viscous depot is no more than about 2 wt % relative to the total weight of the depot. Also disclosed is its use for the prevention and/or treatment of a wound.
Patent NZ-610679-A (NZ)
Title: Method for producing refined vegetable oil
Inventor: BHAGGAN KRISHNADATH
IPC: C11B3/10
Filed: 2011-10-12
Abstract: 610179 Disclosed is a method of producing a refined, bleached and deodorised vegetable oil comprising degumming a vegetable oil, bleaching the degummed oil and deodorising the bleached oil, wherein the degumming, bleaching and deodorising conditions are selected to reduce the content of 3-chloropropane-1,2-diol and esters thereof in the deodorised oil to less than 8 ppm.
Patent NZ-621701-A (NZ)
Title: A transportation receptacle
Inventor: SZAKOS ANDREW
IPC: F25D3/08
Filed: 2014-02-25
Abstract: Disclosed is a transportation receptacle for securely holding a temperature-sensitive product and inhibiting movement of the product during transit, the transportation receptacle comprising: a moulded unitary receptacle body having a base and at least one side wall and a lid that, during use, define a chamber for the product; an insert shaped to be retained within chamber, the insert having one or more recesses or cavities for holding the product; a base cooling member for cooling the product, the base cooling member being shaped to be retained within the receptacle body between the base and the insert; a lid cooling member for cooling the product, the lid cooling member being shaped to be retained within the receptacle body between the insert and the lid; one or more side cooling members for cooling the product, the or each side cooling member shaped to be retained within the receptacle body between the insert and the side wall(s); a base diffuser shaped to be retained within the receptacle body between the base cooling member and the insert; and a lid diffuser shaped to be retained within the receptacle body between the insert and the lid cooling member.
Patent NZ-711004-A (NZ)
Title: Composite railway sleeper
Inventor: DE LISI GIOVANNI MARIA
IPC: E01B3/46
Filed: 2014-01-13
Abstract: A composite railway sleeper (1; 50; 100) comprising an outer coating shell (2; 51; 101) made of composite plastic material and a shaped structural core (3; 52; 102), made of a material comprising at least concrete contained within said outer coating shell (2; 51; 510; 101), wherein said outer coating shell (2; 51; 510; 101) presents in the upper outer face (2a; 51a; 101a) two distinct and opposite groups of grooves (4; 53) suitable to receive the angular guide plates (G) belonging to pre-assembled elastic type fastening systems (64) for the connection of two respective rails (R) with said railway sleeper (1; 50; 100).
Patent NZ-717987-A (NZ)
Title: Baggage conveyance tray
Inventor: FUJIO YOSHIHIKO
IPC: B65D47/40
Filed: 2014-10-17
Abstract: This baggage conveyance tray is for use with a sorting conveyor system for conveying baggage items at an airport, for example. A problem in using conveyance trays with sorting conveyor systems is luggage sliding off the tray. The baggage conveyance tray (1) is equipped with raised wall plate parts (6, 7) protruding on both the front and rear ends of the tray in the length direction thereof, that is, in the conveyance direction, extending in the right-left width direction of the tray. A baggage placement surface (8) located between the front and rear raised wall plate parts (6, 7) is concave along the length direction such that the center part in the right -left width direction is lowered while both the right and left sides are raised. Elongated protrusion parts (13) extending along the right-left width direction of the tray (1) are disposed on the baggage placement surface (8) at appropriate intervals in the length direction of the tray ( 1 ). The elongate protrusion parts (13) have a flat top surface, formed with a rough surface portion thereon, parallel to the front-rear length direction of the tray (1) in a longitudinal sectional shape along the front-rear length direction of the tray (1). The tray (1) is solidly and integrally molded by a molding method in which polypropylene beads are heated and expanded within a mold, and the rough surface portion is formed by means of a steam vent mark of the mold used at the time of molding the tray (1).
Patent NZ-725780-A (NZ)
Title: Method for selecting personalized tri-therapy for cancer treatment
Inventor: LAZAR VLADIMIR
IPC: C12Q1/68
Filed: 2015-06-15
Abstract: The present invention relates to a method for determining the best combinations of at least three drugs for treating cancer, which is based on the determination of the most relevant intervention points for an individual.
Patent NZ-734353-A (NZ)
Title: Improvements for a gas-powered fixing tool
Inventor: CORDEIRO PIERRE
IPC: B25C1/08
Filed: 2016-02-29
Abstract: The invention relates to improved combustion or precombustion chambers for a gas-powered fixing tool having reduced overall size of the chamber, thus reducing the travel time necessary for the flame to cross the chamber longitudinally, which commensurately reduces the duration of a firing cycle by the tool. In particular, described herein are combustion or precombustion chambers for a gas-powered fixing tool, comprising a casing defining a first combustion cavity having a generally elongate form of longitudinal axis X, and a second combustion cavity, ignition means, such as a spark plug being situated at a longitudinal end of said cavity and a longitudinal end of said first cavity, which is opposite said ignition means, being fluidically connected with said second cavity, wherein said first cavity has a variable cross section along said axis X, said first cavity having a generally staged form and comprising at least one first portion of cross section S1 and one second portion of cross section S2, with S1 smaller than S2, said ignition means being situated in said first portion.
Patent NZ-766444-A (NZ)
Title: Factor h binding protein variants and methods of use thereof
Inventor: BEERNINK PETER T
IPC: C07K14/22
Filed: 2015-07-22
Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided. In particular, the variant factor H binding protein comprises an amino acid substitution of the serine at amino acid 223 (S223) with arginine, and has an affinity that is 50% or less of the affinity of fHbp ID 1 for human fH, and wherein the variant induces a bactericidal antibody response to at least one strain of Neisseria meningitidis in a mammalian host.
Patent PT-100897-A (PT)
Inventor: HENRICSON KAJ
IPC: D21C11/06
Filed: 1992-09-24
Abstract: The sulphur content and/or the sulphur compound composition of a melt in a recovery boiler of a pulp mill is adjusted by bringing a gas into contact with the melt. The gas may be a gaseous sulphur compound or a reducing gas. Bringing the gas into contact with the melt increases the sodium sulphide content of the melt while decreasing the sodium carbonate content, so that the sulphidity of the melt increases. The sulphur-containing gas may be produced by pressure heat treatment of black liquor, so that the black liquor burned in the recovery boiler has a lower sulphur content and thereby reduces the boiler sulphur emissions, and boiler corrosion problems.
Patent PT-101461-A (PT)
Title: Liquid nutrient for newborn infants
Inventor: HOFFMEISTER-PAUL ASTRID
IPC: A23L1/304
Filed: 1994-02-14
Abstract: The invention relates to a liquid nutrient for newborn infants or for premature infants, which has a proportion of 10 to 45% by weight of maltodextrin; if a large amount of this liquid nutrient is administered, there is a risk of water intoxication.  The objective of the invention is therefore to prevent this water intoxication, irrespective of the amount of liquid nutrient supplied. To this end provision is made for the addition of electrolytes in the form of sodium, potassium and chloride to the liquid nutrient. By the addition of electrolytes, which are preferably added in the proportion of 20 to 40 mmol/l of sodium, 5 to 20 mmol/l of potassium and 20 to 60 mmol/l of chloride, water intoxication is reliably prevented, even in cases where high doses of the liquid nutrient are administered.
Patent PT-105209-A (PT)
Title: Pá para turbina eólica com baixa emissão de ruído em ambiente urbano
Inventor: HENRIQUES JOAO CARLOS DE CAMPOS
IPC: F01D5/14
Filed: 2010-07-20
Abstract: O PRESENTE INVENTO DIZ RESPEITO A UMA TURBINA EÓLICA DE EIXO HORIZONTAL (1), COM UMA RAIZ (7), UMA EXTREMIDADE (8), UM BORDO DE ATAQUE (9), UM BORDO DE FUGA (10), UM EXTRADORSO CONVEXO (11) E UM INTRADORSO (12) CÔNCAVO, CONVEXO OU EM FORMA DE FORMA DE ¿S¿. É CARACTERIZADA POR SER CONSTRUÍDA COM UM ÚNICO PERFIL COM MODIFICAÇÃO DA SUA LINHA MÉDIA DE MODO A SATISFAZER UMA DISTRIBUIÇÃO DE CARGA DO PERFIL AO LONGO DA CORDA AXIAL DA PÁ, COM REDUÇÃO DO PICO DE PRESSÃO NA SECÇÃO DA PÁ PARA ELEVADOS ÂNGULOS DE INCIDÊNCIA DO ESCOAMENTO E COM RECUPERAÇÃO DE PRESSÃO SUAVE ENTRE O PONTO DE SUCÇÃO MÁXIMA E O BORDO DE FUGA DO PERFIL, PERFIL ESSE QUE É CONSTITUÍDO PELAS SECÇÕES (17) AO LONGO DA ENVERGADURA, CONSTRUÍDAS A PARTIR DAS COORDENADAS ADIMENSIONAIS DA TABELA 1, COM UM COEFICIENTE DE PRESSÃO MÁXIMO DE 1,5 E REDUZIDA EMISSÃO DE RUÍDO DE ORIGEM AERODINÂMICA, EM QUE X/C E Y/C SÃO COORDENADAS ADIMENSIONAIS QUE CORRESPONDEM ÀS COORDENADAS E DIMENSÕES REAIS DO PERFIL DA SECÇÃO DA PÁ DIVIDIDOS PELO COMPRIMENTO DA CORDA (13) DA MESMA USADAS PARA A CONSTRUÇÃO DE UM PERFIL AERODINÂMICO (17).