baber/WOPTO huggingface dataset:
Patent CA-2379212-A1 (CA)
Title: Methods for determining the specificity and sensitivity of oligonucleotides for hybridization
Inventor: BURCHARD JULJA
IPC: C12Q1/68
Filed: 2000-07-14
Abstract: The present invention provides materials and methods which may be used to evaluate one or more different probes and select probes that are optimized for sensitivity and specificity for a particular target. In particularly preferred embodiments, the methods and compositions of the invention can be used to evaluate polynucleotide probes having different nucleotide sequences. The methods and compositions thereby allow a user to select a polynucleotide probe, (e.g.), having a particular nucleotide sequence, that is optimized for sensitivity and/or for specificity for a particular target polynucleotide molecule. In particularly preferred embodiments, the methods and compositions can be used to evaluate a plurality of probes simultaneously, such as on a microarray. Probes evaluated according to the methods of the invention can be selected for and used to detect a variety of molecules, including a variety of polynucleotides, such as genomic polynucleotides (e.g., genomic DNA) and genomic transcripts (e.g.), mRNAs or cDNA sequences derived from there) as well as gene copy numbers of specific transcripts, single nucleotide polymorphisms, (etc.).
Patent CA-2380470-A1 (CA)
Title: Load cell
Inventor: CHIMURA YUKIKO
IPC: G01G3/14
Filed: 2001-05-30
Abstract: A load cell 1 includes a strain body 2, a bridge circuit and a coating film 10.  The bridge circuit is formed of a strain gauge 7 arranged on the strain body 2. The coating film 10 is formed on the strain body 2, covers at least a portion of the strain body 2 attached to a member made of a metal material dissimilar to the strain body and a strain occurring portion of the strain body 2 except for a portion to be attached to the strain gauge 7, includes a coating layer made of resin having a glass transition temperature of 40°C or more, and has an electrical insulating property.
Patent CA-2380718-A1 (CA)
Title: Electronic automatic world-wide time/clock synchronization method
Inventor: SWOFFORD LARRY DON
IPC: G04G9/00
Filed: 2002-04-05
Abstract: A method, system and computer program product for determining time synchronization of a timing device is provided. Geographic position data is obtained from a device associated with the timing device. A current local time is calculated for a location of the device associated with the timing device based on the geographic position data. The timing device is then synchronized with the current local time.
Patent CA-2382049-A1 (CA)
Inventor: PICKARD JAMES
IPC: H02H3/02
Filed: 2000-08-15
Abstract: A system is disclosed for verifying the operativeness of a crowbar circuit which normally protects an electrical device in a series circuit with a power supply. The crowbar circuit includes means for sensing fault current in the series circuit and a crowbar switch responds to the sensing means for protecting the electrical device by directing the fault current away from the electrical device. The system includes verification testing means including a fuse and actuatable pneumatic switch connected together in series for, when said pneumatic switch is actuated, providing a short circuit across the crowbar switch to verify the operativeness of the crowbar circuit which, if not operative, causes the fault current to flow through and blow out the fuse.
Patent CA-2384186-A1 (CA)
Inventor: CHAU CHIU WO
IPC: C12Q1/68
Filed: 2000-09-17
Abstract: L'invention concerne un procédé et un appareil permettant de manipuler des biomolécules et des particules colloïdales au niveau de l'interface entre une électrode isolante, telle qu'une électrode d'oxyde de silicium, et une solution électrolytique. L'assemblage électrocinétique à régulation lumineuse des particules se trouvant au voisinage des surfaces repose sur la combinaison de trois éléments fonctionnels: l'assemblage électrique C.A. à champ induit d'agrégats planaires, la formation de l'interface électrolyte/silicium oxyde/silicium destinée à une commande spatiale du processus d'assemblage, et la commande en temps réel de ce processus d'assemblage par éclairage externe. La présente invention propose une série d'opérations fondamentales permettant de commander de manière interactive la création et le placement de réseaux planaires formés de différents types de particules et de biomolécules, et de modifier la forme et la taille de ces réseaux. Cette invention permet de préparer et de manipuler des échantillons destinés à des analyses diagnostiques et biochimiques dans une structure en réseau, et d'intégrer ces opérations de manière fonctionnelle. En outre, l'invention a trait à une procédé destiné à la création de surfaces de matériaux dotées de propriétés souhaitées, et à la fabrication de composants optiques fixés sur ces surfaces. Elle porte également sur un procédé et un appareil de génération programmable de motifs d'éclairage, et notamment sur un nouveau procédé et appareil servant à générer des motifs d'éclairage et à les projeter sur des surfaces planaires ou sur des interfaces planaires, notamment sur des interfaces constituées d'un semi-conducteur isolant électrolytique tel que décrit ci-dessus. Cela permet de créer des motifs ou des séquences de motifs au moyen d'un logiciel de conception graphique ou de dessin sur un ordinateur personnel, puis de projeter ces motifs ou ces séquences de motifs (motifs à temps variable) sur l'interface au moyen d'un panneau d'affichage à cristaux liquides (LCD), une configuration optique permettant la visualisation de ce panneau LCD sur une surface d'intérêt. L'utilisation de la technologie LCD offre une certaine souplesse et permet de maîtriser la présentation spatiale, les séquence temporelles et les intensités (échelles de gris) des motifs d'éclairage. Cette dernière propriété sert à créer des motifs présentant des changements abrupts d'intensité lumineuse ou des motifs dont les profils d'intensité changent graduellement.
Patent CA-2387118-A1 (CA)
Title: Method and device for mechanically sewing a double chain stitch seam
Inventor: REINDERS PETER
IPC: D05B1/10
Filed: 2000-12-21
Abstract: The aim of the invention is to provide a method for mechanically locking a double chain stitch seam.  The chain stitch is produced by means of an industrial sewing machine comprising a sewing needle and a sewing thread as well as by a main gripper comprising a gripper thread.  The sewing direction is reversed for locking purposes.  The aim of the invention is also to guarantee that the chain stitch seam is sewn in a simple and very precise manner by means of the inventive method and even when the sewing speed is high.  According to the inventive method and after the sewing direction has been reversed, the thread loop which is formed by the sewing needle underneath the web of fabric is received by the main gripper in the stitching rhythm of the sewing needle.   The thread loop is subsequently pushed on the main gripper against the working direction thereof by means of an auxiliary component that is driven in a synchronous manner by the sewing machine.  The needle thread which forms the thread loop is then joined with the gripper head and held in this position underneath the sewing level at a distance from the needle and the main gripper in front of said needle and gripper and in the forward sewing direction by means of said auxiliary component.  The joined thread area is moved in the forward sewing direction and a thread triangle formed by the needle thread rope that forms the loop is stretched in the gripper thread size that extends in parallel in relation to the main gripper and in the gripper thread area that leads to the joined area.  The sewing needle stitches into said triangle.  The thread triangle is subsequently held open by means of the auxiliary component until the next thread loop of the needle thread is formed.   The joined thread area is released by the auxiliary component approximately at the same time.
Patent CA-2388633-A1 (CA)
Title: Hand-held electricity powered corkscrew
Inventor: NIKOLIC DUSAN
IPC: B67B7/04
Filed: 2000-07-13
Abstract: A hand-held electrically powered corkscrew having a tubular body portion (5)  with a longitudinal axis and a handle (4) extending laterally therefrom, sai d body portion having an outer barrel (36) to receive the neck of a bottle in entered relation therein; a rotatable cork auger (10) means substantially co - extensive and co-axial with said barrel, wherein said handle is inclined fro m said body portion at an angle to the longitudinal axis less than 90 degrees to afford comfortable ergonomic use of the corkscrew.
Patent CA-2394602-A1 (CA)
Title: New modulators of dopamine neurotransmission
Inventor: WATERS SUSANNA
IPC: C07D405/04
Filed: 2000-12-22
Abstract: New 3-substituted 4-(phenyl-N-alkyl)-piperazine and 4-(phenyl-N-alkyl)--piperidine compounds of Formula (1), wherein X N, CH, or C, however X may only be C  when the compound comprises a double bond at the dotted line; R1 is OSO2CF3, OSO2CH3, SOR3, SO2R3, COR3, NO2, or CONHR3 and when X is CH or C R1 may also be CF3, CN, F, Cl, Br, or I; R2 is a C1-C4 alkyl, an allyl, CH2SCH3, CH2CH2OCH3, CH2CH2CH2F, CH2CF3, 3,3,3-trifluoropropyl, 4,4,4- trifluorobutyl, or -(CH2) - R4; R3 is a C1-C3 alkyl, CF3, or N(R2)2; R4 is a C3-C6 cycloalkyl, 2-tetrahydrofurane or 3-tetra-hydrofurane, as well as pharmaceutically acceptable salts thereof are disclosed. Also pharmaceutical compositions comprising the above compounds and methods wherein the above compounds are used for treatment of disorders in the central nervous system are disclosed.
Patent CA-2398032-A1 (CA)
Title: Open well plunger-actuated gas lift valve and method of use
Inventor: BOSLEY GORDON E
IPC: E21B43/12
Filed: 2002-08-13
Abstract: A system is provided for unloading accumulated liquids and enhancing the recovery of gas from a reservoir having diminished pressure. An annulus between a tubing string and casing is isolated by a packer and continually pressurized with a slipstream of compressed gas while the well continues to produce. A unique valve positioned in the tubing string is shuttled between a production position in which production fluids are permitted to bypass the valve to the surface and a lift position in which the bypass is blocked and an unloading port is opened to vent high pressure annulus gas to the tubing string above the valve, lifting accumulated liquids with it. Preferably, the valve is actuated to the lift position by the impact of a plunger dropped from a lubricator at the wellhead, when the pressure in the annulus has reached a predetermined threshold. When the gas has been vented and the pressure in the annulus drops, the valve is actuated to the uphole production position as a result of the higher reservoir pressure.
Patent CA-2398150-A1 (CA)
Title: Multi-depth focused resistivity imaging tool for logging while drilling applications
Inventor: BITTAR MICHAEL S
IPC: G01V3/24
Filed: 2001-01-22
Abstract: A resistivity tool for use in an LWD system includes a transmitter array with multiple transmitters (T1, T2, T3) positioned above a pair of receivers (R1, R2). The transmitters (T1, T2, T3) are selectively energized, causing current to be induced in the collar of the tool. The axial current in the tool collar is measured by the pair of receivers (R1, R2) to determine the amount of current that flows into the formation between the receivers (R1, R2). From this, the formation resistivity can be measured for each transmitter to provide multiple depths of investigation. A plurality of discrete electrodes (500) are positioned between the two receivers (R1, R2) to permit imaging of the borehole by obtaining azimuthally sensitive resistivity readings based upon the voltage level at each discrete electrode and the amount of current flowing into the formation.
Patent CA-2401511-A1 (CA)
Inventor: CHEN SHIPING
IPC: G02B21/00
Filed: 2001-03-13
Abstract: La structure de balayage de l'invention comprend un appareil qui transmet la lumière, et reçoit la lumière d'une zone pouvant être excitée par la lumière incidente sur un substrat devant être mesuré par la structure de balayage. L'appareil de transmission et de réception de lumière peut inclure une fibre optique qui comporte une extrémité proximale et une extrémité distale, et transmet une lumière présentant une certaine longueur d'onde ou une lumière présentant plusieurs longueurs d'onde variables pour exciter les échantillons sur le substrat. Cette fibre optique peut également recevoir simultanément une lumière éventuellement émise par des échantillons fluorescents sur le substrat. La structure de balayage peut aussi comprendre un support de la fibre optique pouvant parcourir des distances variables sur le substrat à mesurer ou à examiner. Des supports peuvent inclure des galvanoscanneurs ainsi que des faisceaux de suspension résonnants. Une source optique, p. ex. un laser, peut être couplée optiquement à l'extrémité proximale de la fibre optique. Cette source optique peut présenter une certaine longueur d'onde, mais plusieurs sources optiques présentant chacune une longueur d'onde différente peuvent également être utilisées simultanément par couplage des sources optiques en une seule fibre optique à l'aide de multiplexeurs en longueur d'onde, ou par placement de fibres optiques isolées présentant différentes longueurs d'onde au voisinage les unes des autres. Lorsque la lumière est transmise vers le bas en direction du substrat, à travers la fibre optique, cette dernière est suffisamment proche du micro-réseau du substrat, si bien qu'elle peut recevoir la lumière fluorescente émise.
Patent CA-2402720-A1 (CA)
Title: Door sill assembly having adjustable threshold
Inventor: FLINT RANDY L
IPC: E06B1/70
Filed: 2001-03-21
Abstract: A door sill assembly is provided with an adjustable threshold (22) and is made up of an elongated metal frame (36) for installation on the floor of the doorway. The metal frame is provided with a tongue and sloping sill portion (46), a vertically extending rib (48) and a shelf (50) located below and integrally oriented relative to the rib. The threshold rail (38) is supported on the frame member shelf portion upon two adjustable feet (64) for varying the relative height level of the rail. A plastic threshold cap (40) is sized to fit over the threshold rail and includes a pair of downwardly spaced ribs (82, 84) sized to securely fit over the vertical rib of the frame member to locate the threshold cap and rail relative to the frame member while providing limited vertical adjustment. The interior trim molding (44) is provided which is fixed relative to the frame member and oriented inboard of the threshold cap.
Patent CA-2403152-A1 (CA)
Title: Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
Inventor: JUNG BIRGIT
IPC: A61P11/06
Filed: 2001-03-31
Abstract: The invention relates to bicyclic heterocycles of the general formula (I), wherein R a to R d, A to C and X are defined as in claims 1 to 5. The invention further relates to the tautomers, stereoisomers and salts thereof, especially the physiologically salts with inorganic or organic acids or bases thereof, having valuable pharmacological properties, especially an inhibitory effect on tyrosine kinase mediated signal transduction. The invention further relates to the use of said compounds for treating diseases, especially tumor diseases, diseases of the lungs and the respiratory tract, and to the production of said compounds.
Patent CA-2406007-A1 (CA)
Title: Testing and cut-off device for telephone line
Inventor: BONVALLAT PIERRE
IPC: H04Q1/14
Filed: 2001-04-17
Abstract: A testing and cut-off device, intended to be interposed on a bifilar telepho ne or computer-related line in order to connect two incoming strands to two outgoing strands, comprises a testing well inside which are located, on the one hand, a couple of free terminals (32, 33) corresponding to the two incoming strands and, on the other hand, a couple of free terminals (41, 42)  corresponding to the two outgoing strands, and a cover (59) for closing the well. These two couples of terminals (32, 33, 41, 42) are electrically insulated with respect to one another, when the cover (59) is open, and each  terminal (32, 33, 41, 42) then becoming selectively accessible from the outside by a respective testing plug. The testing and cut-off device further  comprises means incorporating electrical contacts contained in the cover for  effecting the interconnection of these couples of terminals in two's when th e cover (59) is closed on the well. Said interconnection means incorporating electrical contacts contained in the cover (59), also comprise at least one means for galvanically linking the latter with at least one additional electrical member (66, 67) placed outside the well.
Patent CA-2406616-A1 (CA)
Title: Scanner utilizing light pipe with diffuser
Inventor: SAVANT GAJENDRA D
IPC: G06V30/224
Filed: 2001-02-27
Abstract: A scanner that can include a light source (3810) emitting light through a light pipe (3820) to a detector array. The light pipe can include a reflecti ve surface (3822) and a diffuser (3824). The reflective surface can reflect lig ht (3815), directly or indirectly towards the diffuser and the diffuser can diffuse the light out of the light pipe. The light pipe can further include a reflective groove that reflects ligth from the reflective surface towards th e diffuser. The diffuser can diffuse the light to an object that reflects the light to the detector array. The object may be a bar code, paper money, or a ny other object that can be scanned. The diffuser may be a variable diffuser.</ SDOAB>
Patent CA-2408554-A1 (CA)
Title: A method of controlling the display of a browser during a transmission of a multimedia stream over an internet connection so as to create a synchronized convergence
Inventor: WINE WILLIAM
IPC: H04N7/173
Filed: 2001-05-09
Abstract: The present invention relates generally to a system and method of controlling the display of sponsoring, advertising and/or hyperlinks or other web page controls during a multimedia stream transmission over an Internet connection.  Specifically, sponsoring, advertising and/or hyperlinks to accompany multimedia stream transmissions are selected so that they are "thematically appropriate" or "in context" with the content of the multimedia stream. In this way, the content of the sponsor, advertisement and/or hyperlink material is more likely to be properly targeted to the multimedia stream viewing audience. The presentation of the multimedia stream transmission is further enhanced by hyperlinks to related web sites associated with terms being used, details of particular topics, information on particular entities, and other view points.
Patent CA-2409617-A1 (CA)
Inventor: LANGHAM BARRY JOHN
IPC: A61P19/02
Filed: 2001-05-30
Abstract: L'invention concerne une 2,7-naphtyridine contenant des acides squariques représentés par la formule (I) : dans laquelle Ar?1¿ représente un groupe 2,7-naphtyridin-1-yle éventuellement substitué ; L?2¿ désigne une liaison covalente ou un atome ou groupe de liaison ; Ar?2¿ représente une chaîne aromatique ou hétéroaromatique éventuellement substituée ; Alk désigne une chaîne (A), (B), (C) ou (D), où R représente un acide carboxylique (-CO¿2?H) ou un dérivé ou biostère de celui-ci ; R?1¿ désigne un atome d'hydrogène ou un groupe C¿1-6? alkyle ; L?1¿ représente une liaison covalente ou un atome ou groupe de liaison ; Alk?1¿ désigne une chaîne aliphatique éventuellement substituée ; n désigne zéro ou le nombre entier 1 ; R?2¿ désigne un atome d'hydrogène ou un groupe hétéroaliphatique, cycloaliphatique, hétérocycloaliphatique, polycycloaliphatique, hétéropolycycloaliphatique, aromatique ou hétéroaromatique éventuellement substitué. L'invention concerne également les sels, les solvates, les hydrates et les N-oxydes desdits composés, qui, du fait qu'ils peuvent inhiber la liaison des intégrines à leurs liants, sont utilisés dans la prophylaxie et le traitement des troubles immunitaires ou inflammatoires ou des troubles impliquant une croissance ou migration inappropriée de cellules.
Patent CA-2409828-A1 (CA)
Inventor: LAUX VOLKER
IPC: A61P35/04
Filed: 2001-05-29
Abstract: The present invention relates to formulations based on at least one heparin, glycosaminoglycan or heparinoid and on a formulation base with a lipid component and a polymer component. The use of this formulation as drug form for oral administration of at least one heparin, glycosaminoglycan or heparinoid, and also a process for producing the formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as drug form, advantageously using melt extrusion, are described. The lipid component advantageously has active ingredient-promoting properties, while the polymer component is soluble or swellable. At least parts of the lipid component are embedded in a polymer matrix, preferably in the form of a molecular dispersion. The formulations can form emulsions in water or aqueous liquids.
Patent CA-2409974-A1 (CA)
Title: Lactobacillus reuteri glucosyltransferase
Inventor: VAN GEEL SCHUTTEN GERRITDINA H
IPC: A23L29/269
Filed: 2001-05-23
Abstract: The present invention describes a protein having glucosyltransferase activity.  This protein is derived from lactobacilli, which are food-grade microorganisms with the Generally Recognised As Safe (GRAS) status. The protein produces a glucan with a unique structure having 4-linked, 6-linked and 4,6-linked anhydroglucose units or in the presence of suitable acceptors, oligosaccharides. According to the invention lactobacilli capable of producing this glucan using the novel glucosyltransferase can be used as a probiotic or symbiotic.
Patent CA-2410845-A1 (CA)
Inventor: PEDNEAULT PIERRE
IPC: A62C3/02
Filed: 2002-12-04
Abstract: Système d'extraction d'air pour extraire l'air d'un bâtiment en flamme et ainsi déstabiliser les éléments nécessaires à un incendie soient : la chaleur, le combustible et l'oxygène par conséquent lorsqu'il y a élimination de l'oxygène il y a affaiblissement et extinction de l'incendie. Le système est relié à un camion vacuum et se compose d'une chambre de décompression que l'on installe à l'entrée du bâtiment, de plaque vacuum pour les fenêtres, d'une gaine tuyau comprenant un tuyau d'extraction de l'air et un tuyau d'eau rafraîchissant, jauge de sécurité de pression à zéro et une valve de pression zéro pour éliminer les dangers d'implosion, sac d'étanchéité pour obstruer les entrées et les sorties d'air du bâtiment . Au lieu d'approvisionner l'incendie en oxygène, le système en extrait cette dernière et ainsi élimine la fumée et abaisse la température du foyer d'incendie .
Patent CA-2411487-A1 (CA)
Title: Remote monitoring of consumables for a computer to plate imaging system
Inventor: MANNESS DOUGLAS
IPC: G06Q10/08
Filed: 2002-11-12
Abstract: In a system for monitoring the usage of consumable items in a computer to plate imaging line, usage data is transferred to a remote management information system (MIS), which may be run by a media vendor or other service company. The remote MIS system monitors the consumable inventory for a plant against pre-determined order points.      An order is initiated if the inventory falls below the pre-determined order point.