baber/WOPTO huggingface dataset:
Patent DE-68921282-T2 (DE)
Inventor: ALONSO KENNETH
IPC: C12P21/08
Filed: 1989-09-21
Granted: 1995-06-22
Abstract: Human-human hybridomas have been produced by the method of the invention which sensitizes human tumor cells in the human spleen cells prior to fusion with human fetal marrow, human lymphoblastoid or human plasma cell lines. The monoclonal and polyclonal antibodies produced by the hybridomas disclosed avoid the immune reactions caused by antibodies produced by interspecies hybridomas. IgM and IgA lines have been raised for use against each of the following tumors:  colon adenocarcinoma  lung adenocarcinoma  breast adenocarcinoma  mucoepidermoic carcinoma  hepatocellular carcinoma  leiomyosarcoma  melanoma  neurofibrosarcoma  squamous carcinoma of the tongue  squamous carcinoma of the anus  pancreas adenocarcinoma  lymphoblast (acute leukemia)  Mycosis Fungoides  oat cell carcinoma  prostate adenocarcinoma  esophageal squamous carcinoma  Ewing's  gastric adenocarcinoma  biliary adenocarcinoma  ovary adenocarcinoma (mucinous)  ovary adenocarcinoma (serous)  lymphoblast (lymphoma)  alveolar cell carcinoma glioblastoma n
Patent DE-68922292-T2 (DE)
Inventor: BES RICHARD FRANCOIS THEODOR
IPC: C09B67/02
Filed: 1989-12-19
Granted: 1995-09-21
Abstract: The invention relates to a method for the production of a pulverulent composition containing dyestuff and/or pigment composition particles, wherein in a plastic dispersed dyestuff and/or pigment composition particles are formed by mixing an aqueous paste containing dyestuff and/or pigment particles in a plastic emulsion, removing water and pulverizing the mass obtained. The dyestuff or pigment is preferably chosen from the spinel pigments, carbon black and organic pigments, and transparent iron oxide; the plastic is preferably chosen from polystyrene, polyethene, polyvinyl chloride and polyvinyl acetate. The particles as obtained can be mixed with a molten wax composition, such that the dyestuff and/or pigment composition particles de-agglomerate, whereafter the mixture is dispersed and left to solidify. The de-agglomerated particles are more particularly smaller than 5  mu  .
Patent DE-68923498-T2 (DE)
Inventor: PARR ALAN JAMES
IPC: B29C67/00
Filed: 1989-08-17
Granted: 1996-04-04
Abstract: A method of producing resin articles from a resin reaction system comprises the step of subjecting the resin reaction system to high frequency vibration during reaction.
Patent DE-68927921-T2 (DE)
Inventor: THILL GREGORY PATRICK
IPC: C12N1/16
Filed: 1989-05-12
Granted: 1997-07-17
Abstract: A process for the enhanced production of antigenic particles consisting essentially of hepatitis B S protein and preS2 protein. Also disclosed are novel DNA molecules and hosts transformed with these molecules.
Patent DE-68929277-T2 (DE)
Inventor: GRINTER TREVOR JOHN
IPC: C07D473/00
Filed: 1989-07-18
Granted: 2001-08-23
Abstract: A process for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt thereof: <CHEM>  which process comprises reacting a compound of formula (I): <CHEM> wherein the amino group is optionally protected, Y is iodo, optionally substituted benzylthio or (phenacylmethyl)thio, with a compound of formula (III): <CHEM> wherein Q is a leaving group, Rx and Ry are protected hydroxymethyl or acyloxymethyl, or group(s) convertible to hydroxymethyl or acyloxymethyl; and Rz is hydrogen or a group convertible thereto; and thereafter converting Y to X is hydroxy by means of hydrolysis, or to X is hydrogen by means of reduction; converting Rx and Ry when other than hydroxymethyl or acyloxymethyl, to hydroxymethyl or acyloxymethyl, optionally converting Rx/Ry hydroxymethyl to acyloxymethyl or vice versa, deprotecting the 2-amino group where necessary and converting Rz, (when other than hydrogen) to hydrogen; and optionally forming a pharmaceutically acceptable salt thereof.
Patent DE-69001929-T2 (DE)
Inventor: GILLIS HERBERT RUSSEL
IPC: C08G18/50
Filed: 1990-03-08
Granted: 1993-11-04
Abstract: A polyamine as obtainable by the hydrolysis of the reaction product of :(a) an organic compound having the formula :orwherein Q represents an organic residue, X represents oxygen or sulphur, Y represents a halogen atom or an aryloxy group, R is a polyvalent hydrocarbon radical, m is a whole number from 1 to 3 and n is a whole number of at least 2, and(b) a polyfunctional compound containing an amine group and at least one hydrolysable imino group.
Patent DE-69012594-T2 (DE)
Inventor: MCKEON ALICE
IPC: G01R31/28
Filed: 1990-01-08
Granted: 1995-05-04
Abstract: An analogue circuit or unit under test (34) is tested utilising automatic test equipment (30) and an interface unit (35) to apply stimuli to the circuit (34), the stimuli including supply potentials. A computer (32) analyses the circuit (34) as a network of nodes and modules to deduce a set of ranges of values at selected nodes, the ranges being determined from the set of the stimuli and a resultant set of test measurements, taken from nodes of the circuit by means of the interface (35) and automatic test equipment (30), taking into account tolerances in the stimuli, the measurements and the nominal parameters of components of the circuit. If there is inconsistency among the derived ranges the computer (32) treats as potentially faulty any module which could remove the inconsistency if the constraints imposed by that module were suspended. The computer (32) controls an iterative, hierarchical process involving repetition of the sequence of steps using different sets of stimuli and/or measurements and/or different analyses of the circuit into nodes and modules, in particular with analysis in terms of successively smaller modules. In this way, the location of faults can be progressively narrowed down and corresponding output information can be given in a device (40) such as a VDU or printer.
Patent DE-69014618-T2 (DE)
Inventor: GUTHRIE RODERICK I L
IPC: G01N33/20
Filed: 1990-04-27
Granted: 1995-04-13
Abstract: PCT No. PCT/CA90/00140 Sec. 371 Date Oct. 28, 1991 Sec. 102(e) Date Oct. 28, 1991 PCT Filed Apr. 27, 1990 PCT Pub. No. WO90/13014 PCT Pub. Date Nov. 1, 1990.A molten metal inclusion sensor comprises a single use disposable probe which is detachably connected to a support member. The probe may comprise a tube of heat resistant material having an inner electrode mounted on its interior wall and an outer electrode mounted on its exterior wall, the molten metal entering the tube interior through an orifice in its wall past a jet-preventer insert upon its immersion in the molten metal, whereupon the flow of metal with entrained inclusions is monitored by measuring the voltage between the electrodes. Alternatively the tube may be of electrically-conductive heat-resistant material and constitute the inner electrode. The flow may be assisted by a reduced pressure established within the tube, or may be slowed by a positive pressure to maintain the Reynolds number of the flow below 2000. The tube interior is divided by a narrow bore into two compartments so that metal enters one compartment and freezes in the bore so that it cannot enter the second compartment, protecting the vacuum source if provided and establishing the quantity of metal entering the probe. The orifice is closed by a meltable cover and the cover is protected by a meltable shield to enable the probe to be passed through an overlying slag layer without entry of slag to the probe interior. Various suitable materials are disclosed for the electrodes and for the body of the probe which should have a useful life in the bath of about 2 minutes.
Patent DE-69019077-T2 (DE)
Inventor: TANAKA SHOJI
IPC: C12N15/09
Filed: 1990-01-17
Granted: 1995-08-31
Abstract: Processes for the production of a peptide of the formula (III): R-X-NH2, wherein X-NH2 represents a C-terminal  alpha -amidated amino acid and R represents a remaining portion of the peptide, starting form any step in a series of the following steps:  (1) obtaining a fused protein of the formula (0):  P-R-X-Gly-B, wherein P represents a partner protein of the fused protein, X represents any amino acid residue, Gly represents a glycine residue, B represents a C-terminal basic amino acid or a basic oligopeptide, and R represents a remaining portion of the peptide, by a gene recombination method; (2) recovering the fused protein; (3) cleaving the fused protein to form a partner protein (P) and a peptide of the formula (I):  R-X-Gly-B; (4) separating the peptide (I) from the partner protein (P) on the basis of the difference of the isoelectric points thereof; (5) hydrolyzing the peptide (I) with carboxypeptidase B to form an intermediate peptide of the formula (II) R-X-Gly; and (6) treating the peptide (II) with a C-terminal  alpha -amidating enzyme.
Patent DE-69026784-T2 (DE)
Inventor: MITTENTHAL LOTHROP
IPC: H04L9/06
Filed: 1990-10-03
Granted: 1996-12-12
Abstract: Methods and apparatus for modulo 2 addition based encryption by block substitution techniques which allows use of the substitution scheme with relatively simple hardware. The block substitution, a one to one mapping of n bit binary numbers onto themselves, is based on the fact that certain permutations of the n bit binary numbers define a block substitution by modulo 2 addition of one permuted set of numbers to another, and that a subset of these define equations having an additive relationship when viewed as vectors. This allows the simple changing of the transformation on a frequent basis. Various properties of the transformations and methods of using the same are disclosed.
Patent DE-69028807-T2 (DE)
Inventor: HAYASAKI KIMIYUKI
IPC: B41J2/05
Filed: 1990-06-29
Granted: 1997-02-27
Abstract: A liquid injection recording head includes a drive integrated circuit (30) having a circuit (33) for setting a recording current energization time for electrothermal conversion elements. The setting circuit has a counter. The recording current energization time data can be set in the counter in the setting circuit in synchronism with a signal obtained by frequency-dividing a recording data transfer clock or with this clock signal supplied to a circuit arranged in the drive integrated circuit to align recording data.
Patent DE-69032550-T2 (DE)
Inventor: EFFLAND RICHARD CHARLES
IPC: A61K31/4427
Filed: 1990-06-26
Granted: 1999-02-18
Abstract: There are described compounds of the formula <CHEM>  where  n is 0 or 1; X is O or NR2, R2 being hydrogen, loweralkyl or loweralkylcarbonyl; Z is NO2 or NHR where R is hydrogen, loweralkyl, arylloweralkyl or loweralkylcarbonyl; and  R1 is <CHEM>   <CHEM> wherein R3 is hydrogen, loweralkyl or loweralkylcarbonyl; m is 1 or 2; each R4 is independently hydrogen or loweralkyl; and Y is hydrogen, halogen, loweralkyl, loweralkoxy or trifluoromethyl; which compounds are useful as topical antiinflammatory agents for the treatment of various dermatoses.
Patent DE-69033977-T2 (DE)
Inventor: MURAKAMI SHUJI
IPC: G11C29/04
Filed: 1990-02-26
Granted: 2002-11-28
Abstract: A circuit for repairing a defective memory cell is provided between a row or column decoder and a memory cell array. When the decoder has n output lines, the memory cell array includes at least (N + 1) row or column lines, where n is an integer. The repair circuit includes connection circuit for connecting the output lines of the decoder to the row or column lines, and a circuit for defining the connection of the connection circuit. The connection circuit includes n switching elements each of which is operable to connect one output line of the decoder to at least two row or column lines. The defining circuit defines the connection path of each switching element such that the output lines of the decoder is connected in one to one correspondence to successively located row or column lines excluding a row or column line connecting a defective memory cell. The defining circuit includes a series of laser programmable fuse elements provided between an operation voltage supply and a ground line. The repair circuit occupies a reduced area of a chip because of no spare decoder and nor program circuit and it carries out a reliable and fast memory repair because of the, reduced number of the fuse elements to be blown off. <IMAGE>
Patent DE-69100433-T2 (DE)
Inventor: GRAVELAND ARIS
IPC: A21D13/00
Filed: 1991-06-24
Granted: 1994-01-20
Abstract: Glucose oxidase is used to prevent the appearance, after thawing, of grey spots in frozen doughs. In particular, this can be used in puff pastry doughs.
Patent DE-69102049-T2 (DE)
Inventor: SOERENSSON OLLE
IPC: C11D3/08
Filed: 1991-10-28
Granted: 1994-09-01
Abstract: The invention concerns a solid alkalimetal silicate having a molar ratio SiO2:M2O from about 1.5 to about 3, in which M is an alkalimetal and substantially consists of sodium and optionally potassium. The silicate contains from about 7 to about 20% by weight of sodium carbonate based on the dry material and has a water content from about 14 to about 22% by weight. Further, the invention concerns a method of preparing the silicate above, use of the same and cleaning agent compositions containing such a silicate.
Patent DE-69104782-T2 (DE)
Inventor: DECAUDIN ROBERT
IPC: B01J23/72
Filed: 1991-06-21
Granted: 1995-05-18
Abstract: Process for the preparation of unsaturated bromides by reaction of hydrobromic acid with unsaturated alcohols, characterised in that the reaction is carried out in the presence of a metal or of a metal salt as catalyst. It is particularly useful for the production of allyl bromide.
Patent DE-69107049-T2 (DE)
Inventor: CAILLOT RAYMOND
IPC: H01Q1/12
Filed: 1991-11-27
Granted: 1995-06-22
Abstract: The antenna base (1) comprises, on the one hand, a tube (2) in which an antenna wire can slide and, on the other hand, an oblique lateral socket (4) fixed to the tube, and to which socket is connected up a coaxial cable intended to connect the base of the antenna to a receiver set. The base comprises a part (8) in light alloy, in particular zamac, able to establish a mechanical link between the tube (2) and the socket (4) so that the angle of obliqueness of the socket relative to the tube is ensured. The light alloy part (8) includes, in the region of the base tube, an open cylindrical sector (9) extending over a circumferential fraction, this sector including protuberances (11) in the radial direction which enable the said part (8) to be fixed onto the tube (2) by riveting these protuberances. <IMAGE>
Patent DE-69110864-T2 (DE)
Inventor: JORGENSEN PER
IPC: C12N15/09
Filed: 1991-01-18
Granted: 1996-03-28
Abstract: PCT No. PCT/DK91/00013 Sec. 371 Date Jul. 27, 1992 Sec. 102(e) Date Jul. 27, 1992 PCT Filed Jan. 18, 1991 PCT Pub. No. WO91/10732 PCT Pub. Date Jul. 25, 1991This invention relates to an enzyme which exhibits cellulase activity and is producible by a strain of Bacillus sp., NCIMB 40250, or a related Bacillus sp. strain, or a derivative of said cellulase. This invention also relates to an enzyme which comprises a core region derived from an endoglucanase combined with a cellulose-binding domain derived from another cellulase, or which comprises a core region derived from another cellulase combined with a cellulose-binding domain derived from an endoglucanase.
Patent DE-69112416-T2 (DE)
Inventor: WENDEBERG STAFFAN
IPC: B62D7/15
Filed: 1991-10-15
Granted: 1996-02-29
Abstract: Hydraulic steering device for steering the wheels (6) on a rear axle (5) of a truck relative to its front wheels (2). The wheels on the rear axle are steered by a servo motor (20) in a high-pressure circuit (19). The servo motor is controlled by a control valve (22), which is operated by a slave cylinder (14) in a separate low-pressure circuit (12). The displacement of the slave cylinder follows the displacement of a master cylinder (13) coupled into the low-pressure circuit, said master cylinder being coupled to the steering mechanism (8, 30) of the front wheels in order to provide a piston displacement dependent on the degree of turning of the front wheels.
Patent DE-69114002-T2 (DE)
Inventor: FANTACCI GIANFRANCO
IPC: B63H11/103
Filed: 1991-08-09
Granted: 1996-04-18
Abstract: The invention relates to a water jet propulsion apparatus for a vessel or a watercraft, in which the pump impeller (8) is fed with sea water only in its lower half through a water-inlet opening (15) provided at the forward end of the tubular impeller housing (1) underneath the level of the axis of the impeller shaft (7). If necessary, also the upper half of the pump impeller (8) may be fed with the exhaust gases from the motor, and/or with the motor-cooling water through an auxiliary inlet opening (16) provided over the level of the axis of the impeller shaft (7). <IMAGE>
Patent DE-69120393-T2 (DE)
Inventor: ROED GJERLOFF
IPC: A61B5/1477
Filed: 1991-02-04
Granted: 1997-02-06
Abstract: PCT No. PCT/DK91/00031 Sec. 371 Date Oct. 6, 1992 Sec. 102(e) Date Oct. 6, 1992 PCT Filed Feb. 4, 1991 PCT Pub. No. WO91/12523 PCT Pub. Date Aug. 22, 1991.The glass electrode comprises a membrane of ion sensitive glass. The membrane comprises a composite material consisting of a matrix of ion sensitive glass and a dispersed filling material therein having higher tensile strength than the matrix. The membrane of the glass electrode is particularly resistant to mechanical stress and the glass electrode is i.a. applicable in a tc Pco2 electrode of the Severinghaus-type.
Patent DE-69121046-T2 (DE)
Inventor: GOTOH TETSUYA
IPC: G02F1/065
Filed: 1991-04-12
Granted: 1997-01-09
Abstract: An organic nonlinear optical crystal having a secondary nonlinear optical effect, a process for producing the same, and various secondary nonlinar optical elements prepared therefrom. This crystal is a laminated organic nonlinear optical crystal comprising a plurality of noncentrosymmetrical organic single crystal layers, wherein the single crystal layers satisfy the following requirements: (1) al least two of the single crystal layers are in optical contact with each other, (2) at least two of the noncentrosymmetrical organic single crystal layers in optical contact with each other have refractive indices different from each other, and (3) at least one of the single crystal layers has an optically smooth crystal face.
Patent DE-69133383-T2 (DE)
Inventor: CRESPI B
IPC: C12N9/02
Filed: 1991-10-10
Granted: 2004-09-09
Abstract: An immortal human cell line stably expressing a multiplicity of cytochrome P450s is provided. Preferably, the cell line is MCL-5, which stably expresses cytochrome P450 IA1, IA2, IIA3, IIIA4, and IIE1, as well as microsomal epoxide hydrolase. The cell line is useful in mutagenicity, toxicity and metabolism studies.
Patent DE-69228564-T2 (DE)
Inventor: PARK CHUNG
IPC: C08J9/12
Filed: 1992-12-17
Granted: 1999-09-02
Abstract: Disclosed is a process for making low density, dimensionally-stable, extruded propylene polymer foam comprised primarily of an expanded propylene polymer material wherein the foam has a blowing agent comprising at least 15 percent by weight of one or more inorganic blowing agents. The foam has a density of from 10 to 150 kilograms per cubic meter, and an average cell wall thickness of less than 35 micrometers. Further disclosed is a foam obtainable from the process.
Patent DE-69311549-T2 (DE)
Inventor: DETHIER ALFRED
IPC: F22B29/04
Filed: 1993-04-30
Granted: 1997-11-13
Abstract: PCT No. PCT/BE93/00092 Sec. 371 Date Dec. 28, 1994 Sec. 102(e) Date Dec. 28, 1994 PCT Filed Apr. 30, 1993 PCT Pub. No. WO93/23702 PCT Pub. Date Nov. 25, 1993The invention relates to a boiler (1) wherein at least one steam generating circuit comprises an ejector (25) capable of providing induced circulation of water in the boiler in normal operating conditions. The corresponding water/steam separation reservoir (17) is arranged at any height with respect to the outlet collector (manifold) (15) of the evaporator device (11) of said circuit.
Patent DE-69315072-T2 (DE)
Inventor: YALOVEGA NIKOLAI VASILIEVICH
IPC: H02K3/28
Filed: 1993-06-29
Granted: 1998-04-16
Abstract: A stator comprises a magnetic circuit (1) whose separate slots internally accommodate coil groups (2, 3, 4: 2<1>, 3<1>, 4<1>) of two three-phase delta- and star-connected windings. Vectors (BU1V1, BV1W1, BW1U1; B1U1, B1V1, B1W1) of magnetic induction of each coil group (2, 3, 4; 2<1>, 3<1>, 4<1>) intersect an axis (5) of the magnetic circuit (1). The coil groups (2-2<1>; 3-3<1>; 4-4<1>) of like phases overlap one another in a cross-section of the stator and are displaced through 30 electrical degrees, while the three-phase windings are made close in power. In total, this provides substantially time and geometric orthogonality between pairs of the vectors (BU1V1 - B1W1; BW1U1 - B1V1; BV1W1 - B1U1) of one phase of one three-phase winding and the coil groups (3<1>, 4<1>, 2<1>) of the next phase of another three-phase winding.
Patent DE-69322672-T2 (DE)
Inventor: BOURREAU FRANK-YANN
IPC: B01F29/64
Filed: 1993-03-16
Granted: 1999-05-20
Abstract: Process for continuous surface treatment of particles in motion by means of a treatment agent, characterised in that     - the treatment agent is brought simultaneously and continuously; - the particles are in the form of elemental volumes in plug continuous lengthwise translation principal motion, the particles of each volume being additionally and simultaneously subjected to at least one rotational motion in a direction transverse to that of the main motion, and at least one vertical motion in an elemental space, in which all the walls in contact with the particles are continuously movable.   It applies to particles of all kinds, for example seeds.
Patent DE-69332519-T2 (DE)
Inventor: LEVER MICHAEL
IPC: A61K48/00
Filed: 1993-03-01
Granted: 2003-07-17
Abstract: The present invention relates to vectors and their use in gene transfer, In particular the invention provides a vector comprising nucleotides corresponding to the packaging nucleotides of a lentivirus, a heterologous gene, and, flanking the packaging nucleotide and the heterologous gene, sequences corresponding to those within and near the sufficient lentivirus LTR, for packaging, reverse transcription and integration of the vector into target cells and expression of the heterologous gene wherein said nucleotides comprise those corresponding at least substantially to the lentivirus 5' leader sequence and REV-responsive region.
Patent DE-69413024-T2 (DE)
Inventor: FELICI FRANCO
IPC: A61K35/76
Filed: 1994-05-05
Granted: 1999-02-04
Abstract: A process for the preparation of immunogens or diagnostic reagents that mimic an antigen or a pathogenic organism specific to a disease, essentially characterized by the following operations: identification of at least one antibody that reacts with the antigen or pathogenic organism specific to the disease; construction of phage libraries which display on the surface of the capsid oligopeptides, expressed from random sequence oligonucleotidic inserts introduced into a gene coding for a phage capsid protein using genetic manipulation techniques (for example, using a plasmid engineered for the purposes of the invention, the genetic map of which is shown in the figure); selection of the phages that display on the surfaces of the capsid antigenic oligopeptides recognized by said antibody; optional use of the selected phages and/or fragments thereof and/or their derivatives for the formulation of diagnostic kits for the specific pathogenic agent, or in general for the disease, including immunological disorders typical of so-called autoimmune diseases, with known or unknown etiology and/or pathogenesis; optional use of the selected phages and/or fragments thereof and/or their derivatives to induce a tolerance of the phenomena of hypersensitivity and/or allergy to compounds and/or natural or synthetic preparations; optional immunization of an organism by means of the selected phages and/or fragments thereof and/or their derivatives; and optional verification of the presence, in the serum of the immunized organism, of antibodies that recognize the above antigen or organism specific to the disease.