baber/WOPTO huggingface dataset:
Patent CA-3073257-A1 (CA)
Inventor: BAE HYUNSU
IPC: A61K38/16
Filed: 2018-04-30
Abstract: The present invention relates to a composition including melittin as an active ingredient for removing an M2-type tumor-associated macrophage (TAM), and more specifically, the present invention relates to a composition exhibiting an effect of selectively suppressing only M2-type tumor-associated macrophages among tumor-associated macrophages. The composition according to the present invention only suppresses M2-type tumor-associated macrophages without affecting M1-type tumor-associated macrophages or cancer cells, thus exhibiting anti-cancer and metastasis suppressing effects by blocking angiogenesis through control of the microenvironment of cancer cells, while reducing the side-effects of existing anti-cancer effects.
Patent CA-3073436-A1 (CA)
Inventor: EWELL EMILY STEED
IPC: D06M15/564
Filed: 2018-08-21
Abstract: The present invention relates to a multi-layer, breathable garment lining that can be re-used and is leakproof, and which has absorbent, antimicrobial, impermeable and vapour-dispersive properties. Such a lining is designed to prevent the leakage of body fluids, such as sweat, blood, vaginal fluids, menstrual fluid, urine, breast milk or post-surgery fluids.
Patent CA-3073949-A1 (CA)
Inventor: QUINN DEBORAH
IPC: A61M16/06
Filed: 2018-08-29
Abstract: L'invention concerne des méthodes d'utilisation d'oxyde nitrique inhalé pour le traitement de l'hypertension pulmonaire et/ou l'amélioration de la saturation en oxygène chez un patient souffrant d'une non-uniformité du rapport ventilation-perfusion (V/Q) et/ou d'une hypertension pulmonaire associée à une affection pulmonaire.
Patent CA-3075369-A1 (CA)
Inventor: VOTOLATO EARL
IPC: B26B27/00
Filed: 2013-07-10
Abstract: A cutting apparatus comprises a first arm, an opposable second arm, a first blade and a second blade orthogonal to the first blade. The first arm comprises or is coupled to a blade enclosing material that partially encloses the first blade at the first end and the second end in a manner that leaves the central portion of the blade unenclosed. The opposable second arm comprises or is coupled to a raised portion made of a first material. The raised portion partially encloses an anvil made of a second material different from the first material. A first segment of the central portion is sized and dimensioned to physically contact the raised portion and/or the anvil. The second blade is partially embedded in and extends entirely within a thickness of the first arm in a manner that exposes a portion of the second blade at a cutout.
Patent CA-3076658-A1 (CA)
Title: Method and system for vented rollout switch
Inventor: JOYNER GEORGE LEE
IPC: F24D19/10
Filed: 2020-03-23
Abstract: A furnace includes a gas burner exposed to a heat-exchange tube. An inducer is fluidly coupled to the heat-exchange tube and configured to induce draft air through the heat-exchange tube. A regulator is fluidly coupled to the gas burner. A  rollout shield is disposed adjacent to the gas burner. A rollout switch is disposed in the rollout shield. The rollout switch is electrically coupled to the regulator. At least one vent is formed through the rollout shield adjacent to the rollout switch. The vent provides a path for a rollout flame to the rollout switch.  The at least one vent is disposed on at least two sides of the rollout switch.
Patent CA-3077279-A1 (CA)
Inventor: ASHE WESTLEY S
IPC: G01B7/004
Filed: 2020-03-27
Abstract: Il est décrit un système comprenant un émetteur magnétique configuré pour générer des champs magnétiques; un capteur magnétique configuré pour produire des signaux d'après des caractéristiques des champs magnétiques; et au moins un système informatique configuré pour : entraîner la génération, par lémetteur magnétique, dune première pluralité de champs magnétiques à une première fréquence; recevoir une première pluralité de signaux du capteur magnétique; déterminer des données indicatives dune position et orientation du capteur magnétique à une première position du capteur magnétique; déterminer un terme de distorsion qui correspond à une première position du capteur magnétique; entraîner la génération, par lémetteur magnétique, dune troisième pluralité de champs magnétiques à la première fréquence; recevoir une troisième pluralité de signaux du capteur magnétique; et déterminer une deuxième position et orientation du capteur magnétique par rapport à lémetteur magnétique dans laquelle la première fréquence est supérieure à la deuxième fréquence.
Patent CA-3077518-A1 (CA)
Title: Synthetic antibodies against vegf and their uses
Inventor: FELLOUSE FREDERIC
IPC: C07K16/22
Filed: 2017-09-07
Abstract: 1TEM
Patent CA-3077630-A1 (CA)
Title: Adenovirus vectors and uses thereof
Inventor: UIL TACO GILLES
IPC: C12N15/86
Filed: 2018-10-30
Abstract: Provided herein are chimeric adenoviral vectors. The provided chimeric adenoviral vectors can be used to induce a protective immune response in a subject.
Patent CA-3077786-A1 (CA)
Title: Systems and methods for networked music playback
Inventor: COBURN ARTHUR
IPC: H04N21/242
Filed: 2012-12-21
Abstract: A method comprises: detecting a first input comprising an identification of a playback device; detecting a second input comprising an identification of an item on a controller, wherein multimedia content associated with the item is retrievable from a content provider; detecting a trigger, wherein the trigger is not the first input or the second input; and sending, in response to detecting the trigger, information regarding the multimedia content from the controller to the playback device, wherein the information comprises an identification of the multimedia content for playback by the playback device, and wherein the information causes (a) the playback device to retrieve, independent of the controller, the multimedia content from the content provider and (b) playback of the retrieved multimedia content.
Patent CA-3079665-A1 (CA)
Title: Plungers for drug delivery devices
Inventor: JAZAYERI JULIAN
IPC: A61M5/20
Filed: 2018-10-09
Abstract: A plunger configured as described herein provides geometry optimizations to minimize friction magnitude and variability during use by maintaining low deformation under large extrusion forces. More specifically, plunger embodiments described herein minimize a contact area between the plunger and a syringe or chamber, while also maintaining high contract pressures to maintain container closure integrity. Moreover, the plunger embodiments are configured to have minimal or no increase in the contact area under high loads associated with the delivery of viscous products.
Patent CA-3080277-A1 (CA)
Title: All-in-one lyophilized multivitamin emulsion for parenteral application
Inventor: ASSEGEHEGN GETACHEW
IPC: A61K9/107
Filed: 2018-10-22
Abstract: The invention relates to lyophilized products and reconstituted emulsions for parenteral application, which comprise all the 13 essential vitamins (A, D, E, Kl, C, B1, B2, B3, B5, B6, B7, B9, and B12) in a single container, as well as to methods for preparing them.
Patent CA-3084031-A1 (CA)
Title: Support pour la conservation d'echantillons biologiques et procede correle de production
Inventor: MARTELLO GIORGIO
IPC: B01L3/00
Filed: 2018-11-29
Abstract: Un support (1) pour la conservation d'un échantillon de matériau biologique comprend au moins un corps sensiblement rigide (6) en matière plastique moulée, comprenant au moins une première ouverture traversante (13) et au moins une première partie (3) d'une matrice absorbante (2) appropriée pour la conservation d'un échantillon de matériau biologique, fixée à l'intérieur de la première ouverture traversante (13). La première partie de la matrice absorbante (3) a au moins une première partie (28, 29) sans support à partir du corps (6) et suspendue à l'intérieur de la première ouverture traversante (13), la première partie (28, 29) étant directement accessible au contact.
Patent CA-3084848-A1 (CA)
Title: Crystal form of renal outer medullary potassium channel inhibitor and preparation method thereof
Inventor: WU GUAILI
IPC: C07D405/14
Filed: 2018-12-05
Abstract: The present invention provides a crystal form of a renal outer medullary potassium channel inhibitor and a preparation method thereof. In particular, the present invention provides crystal form III of a L-tartrate of a renal outer medullary potassium channel (ROMK) inhibitor (I) and a preparation method thereof. The crystal form III has good chemical stability and crystal form stability, and the crystallization solvent used has low toxicity and residue. Thus, the present invention can be better used in clinical treatment.
Patent CA-3085337-A1 (CA)
Inventor: BEIGELMAN LEONID
IPC: A61P31/00
Filed: 2018-12-14
Abstract: L'invention concerne des composés, des compositions et des méthodes pour traiter des maladies, des syndromes ou des troubles qui sont affectés par la modulation de STING. De tels composés sont représentés par la formule (I) suivante : dans laquelle B2,X2, R2a, R2b, R2c, Z-M-Y, Y1-M1Z1, B1, X1, R1a, R1b, R1c sont tels que définis dans la description.
Patent CA-3086820-A1 (CA)
Inventor: ASADA TAKUMI
IPC: A61K47/36
Filed: 2018-10-18
Abstract: Provided is a method for manufacturing a particle coated with fine particles capable of coating. A method for manufacturing a particle coated with fine particles capable of coating, the manufacturing method characterized by including a step for adding fine particles capable of coating to an inner core including a polymer and a target component, and, while rolling the mixture, performing coating while spraying a solvent capable of dissolving the polymer, the particle coated with fine particles capable of coating being a target-component-containing hollow particle which is coated.
Patent CA-3087655-A1 (CA)
Inventor: BASU SUJAY
IPC: A61P29/00
Filed: 2019-01-04
Abstract: The present disclosure relates to a series of tricyclic compounds, their tautomers, polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of treating conditions and diseases that are mediated by adenosine receptor (AR) activity. The disclosure also relates to process of preparation of these tricyclic compounds of Formula I. These compounds are useful in the treatment, prevention or suppression of diseases and disorders that may be susceptible to improvement by antagonism of the adenosine receptor. The disclosure also relates to the process of preparation of the tricyclic compounds, and to pharmaceutical compositions containing them. Formula (I) wherein D represents a tricyclic ring system selected from: Formula (II) or Formula (III).
Patent CA-3088251-A1 (CA)
Inventor: WANG SHUANGFEI
IPC: C02F3/28
Filed: 2020-07-28
Abstract: To promote anaerobic digestion and delay calcification, one or more signal molecules are used to regulate the microenvironment of anaerobic granular sludge. In the process of anaerobic granular sludge treatment of papermaking wastewater, AHLs (N-acyl Hyperserine Lactones) are added to papermaking wastewater before the papermaking wastewater enters the anaerobic reactor. This may occur when the proportion of microorganism in anaerobic granular sludge VSS/TSS is less than 0.6. Further, the addition of the one or more signal molecules changes the community structure of the bacteria and methanogens, promoting anaerobic digestion and delay calcification. Additionally, the microenvironment of granular sludge is regulated by adding one or more micro-signal molecules to improve the number of bacteria susceptible to calcification, improve the anaerobic digestion rate of sludge that has not been calcified, and delay the calcification rate.
Patent CA-3088427-A1 (CA)
Title: Mobile device for detecting the operating parameters of vibrating machines, and a method for use of the device
Inventor: SCHAEFER JAN
IPC: G01M5/00
Filed: 2018-09-07
Abstract: A mobile device for detecting the state parameters and operating parameters of vibrating machines. Measurement data detected by sensor units is wirelessly transmitted an evaluation unit. Each sensor unit is equipped with at least three acceleration sensors oriented orthogonally to each other, a gravity sensor for detecting the orientation/direction of a local coordinate system (Xi, Yi, Zi) defined by the at least three acceleration sensors, and an integrated circuit for processing the measurement data. At least four sensor units form a sensor network. The sensor units are detachably fastenable at a distance from each other with an undetermined orientation/direction to the vibrating machine. The evaluation unit transforms the local measurement data into a superordinate uniform coordinate system (Xo, Yo, Zo) taking into account the measurement data of the gravity sensor.
Patent CA-3088911-A1 (CA)
Inventor: BRAMLETT BRIAN WAYNE
IPC: G11C11/56
Filed: 2019-01-03
Abstract: Provided herein are compositions, devices, systems and methods for generation and use of biomolecule-based information for storage. Further provided are devices comprising addressable electrodes controlling polynucleotide synthesis (deprotection, extension, or cleavage, etc.) The compositions, devices, systems and methods described herein provide improved storage, density, and retrieval of biomolecule-based information.
Patent CA-3089370-A1 (CA)
Inventor: POST STEVEN W
IPC: F23L17/16
Filed: 2020-08-06
Abstract: A motor controller for a burner system includes an inverter that supplies current to a motor that rotates a draft inducer fan. A processor is coupled to the inverter and receives a signal from a system controller, and in response instructs the inverter to supply a first current, during a first period, to the motor to rotate the fan to produce a first mass flow through the burner system, the first mass flow having a first mass flow rate greater than a threshold to actuate a vacuum switch. The processor then instructs the inverter to supply a second current, during a second period starting at an expiration of the first period, to the motor to rotate the fan to produce a second mass flow through the burner system, the second mass flow having a target mass flow rate for normal operation of the burner.
Patent CA-3090644-A1 (CA)
Inventor: SAWADA RITSUKO
IPC: A61K49/00
Filed: 2014-08-26
Abstract: Il est décrit des compositions servant à produit un anticorps ou un fragment fonctionnel de celui-ci agissant contre lantigène Sialyl-Lewisa (sLea). Les compositions selon l'invention comprennent des polynucléotides codant un domaine variable de chaîne lourde et/ou de chaîne légère qui se lie à sLea. L'invention concerne également un anticorps isolé ou un fragment fonctionnel de celui-ci et des procédés de traitement ou de prévention d'une maladie, comme un cancer ou la formation d'une tumeur, l'anticorps ou son fragment fonctionnel comprenant un domaine variable de chaîne lourde et un domaine variable de chaîne légère, qui ont la séquence d'acides aminés présentée ici. De plus, il est décrit un conjugué dun anticorps ou dun fragment fonctionnel de celui-ci soit conjugué à un agent diagnostique, un agent détectable ou un agent thérapeutique, soit fusionné à lun de ceux-ci de manière à former un recombinant. Des méthodes de traitement, de prévention et de diagnostic dune maladie chez un sujet dans le besoin sont également décrites.
Patent CA-3096470-A1 (CA)
Title: Neutron imaging systems and methods
Inventor: RADEL ROSS
IPC: G21K1/02
Filed: 2019-04-11
Abstract: Provided herein are neutron imaging systems (e.g., radiography and tomography) systems and methods that provide, for example, high-quality, high throughput 2D and 3D fast or thermal neutron and/or X-ray images. Such systems and methods find use for the commercial-scale imaging of industrial components. In certain embodiments, provided herein are system comprising a plurality of independent neutron absorber-lined collimators (e.g., 4 or more collimators) extending outwards from a central neutron source assembly.
Patent CA-3096748-A1 (CA)
Title: Novel albicidin derivatives, their use and synthesis
Inventor: SUSSMUTH RODERICH
IPC: A61K31/4439
Filed: 2019-03-28
Abstract: The present invention relates to a chemical compound according to general formula (1).
Patent CA-3096995-A1 (CA)
Title: Set of panels with a mechanical locking device
Inventor: BOO CHRISTIAN
IPC: F16B12/26
Filed: 2019-04-17
Abstract: A method for dismantling a set and a set (1) comprising a first panel (10), a second panel (20a) and a mechanical locking device (30) for locking the first panel (10) to the second panel (20a), wherein the first panel (10) comprises a first edge surface (11) and a first panel surface (12), the second panel (20a) comprises a second panel surface (22), the first edge surface (11) is facing the second panel surface (22) in a locked position of the first and the second panel (10, 20a), the mechanical locking device (30) comprises a panel groove (133) at the second panel surface (22), a flexible tongue (6) positioned in the panel groove (133), a rod-shaped element (31) at the first edge surface (11) and an insertion groove (32) at the second panel surface (22) extending from the second panel surface (22) to the panel groove (133), the rod-shaped element (31) is configured to be inserted into the insertion groove (32) and the rod-shaped element (31) comprises a recess (34), the flexible tongue (6) is configured to cooperate with the recess (34) for a locking of the first panel (10) to the second panel (20a) in a first direction which is perpendicular to the second panel surface (22), and the panel groove (133) extending at an angle a in the second panel (20) in view of the second panel surface (22).
Patent CA-3099468-A1 (CA)
Inventor: ZHENG DUNMIN
IPC: G01S19/00
Filed: 2019-05-07
Abstract: Devices, methods, and systems for uplink synchronization in time division multiple access (TDMA) satellite network. In one embodiment, an earth-based satellite terminal is configured to communicate with a satellite hub through a satellite using the TDMA communication protocol. The earth-based satellite terminal is configured to determine its own location, a location of the satellite, estimate a distance between the location of the terminal and the location of the satellite, determine a Coarse Timing Advance based on the distance that is estimated, and transmit data to the satellite based on the Coarse Timing Advance and the TDMA communication protocol. The Coarse Timing Advance may allow uplink TDMA communication without a preamble transmission on a random access channel, the preamble transmission being required in many conventional systems.
Patent CA-3099627-A1 (CA)
Title: A chain annuloplasty ring, delivery system and related methods
Inventor: SOLEM KRISTIAN
IPC: A61B17/04
Filed: 2019-07-10
Abstract: An at least partial annuloplasty ring for transcatheter cardiac valve treatment is disclosed. The annuloplasty ring has a plurality of separate chain segments serially interlinked and articulated to a chain. The chain has a substantially elongate delivery configuration and a curved deployment configuration. At least one of said chain segments has at least one tissue anchor attached to it, wherein the tissue anchor is movably arranged at least partly within the chain segment in the delivery configuration and protrudes from the chain segment in the deployment configuration in order to anchor with cardiac tissue.
Patent CA-3103614-A1 (CA)
Inventor: BERGESON SUSAN E
IPC: A61K31/65
Filed: 2019-06-13
Abstract: L'invention concerne une méthode de traitement d'un trouble de l'usage de l'alcool (TUA), d'un trouble de l'usage d'une substance (TUS), de l'usage du tabac, de la douleur ou de troubles pro-inflammatoires consistant à : fournir à un sujet une quantité efficace d'une tétracycline modifiée ou d'un dérivé de celle-ci pour atténuer ou éliminer le TUA, le TUS, l'usage du tabac, la douleur, ou le trouble pro-inflammatoire, et la tétracycline modifiée ou le dérivé de celle-ci présentant une liaison réduite à un ribosome microbien et ayant la formule dans laquelle R1 représente un acétyle, R2 représente OH ou un acétyle, R3 représente un acétyle, R4 représente H ou un acétyle, et R5 représente un acétyle.
Patent CA-3103893-A1 (CA)
Inventor: FRANZONE JOHN B
IPC: A24F47/00
Filed: 2019-06-14
Abstract: Capsules are provided for holding material within a vaporization chamber of a personal or portable vaporization device. Each capsule comprises a cap and a cup, each with a corresponding base wall having air inlet/outlet holes therein. The capsules are provided with first and second standoff structures that position the respective capsule to avoid occlusion of the air inlet/outlet holes by surfaces of the oven and/or lid that form the vaporization chamber. During use of the vaporization device, the capsule design encourages air to flow through the material held within the capsule via the air inlet/outlet holes, rather than flowing around the capsule to bypass the material held therein. In some embodiments, the capsules include tamper-resistant features that prevent separation of the cap and cup once assembled, thereby protecting the material held within the capsule.
Patent CA-3103935-A1 (CA)
Inventor: MEMMELAAR BRYAN EDWARD
IPC: G16H50/70
Filed: 2019-06-17
Abstract: L'invention concerne un système pour afficher des objectifs de gestion de maladie à un patient, qui comprend une base de données d'utilisateur comprenant des données de gestion de maladie de patient mesurées ou des données de gestion de maladie de patient dérivées de l'utilisateur, une base de données de contenu comprenant des éléments de contenu associés à des choix de style de vie recommandés et des protocoles de gestion de maladie, et une interface utilisateur interactive. Le système comprend également une mémoire ayant des instructions qui vont, lorsqu'elles sont exécutées sur un processeur, effectuer un procédé comprenant la détermination d'un objectif de patient associé à l'amélioration de la gestion de maladie sur la base des informations d'utilisateur et des protocoles stockés pour la gestion de maladie, et l'affichage de l'objectif de patient à l'utilisateur sur l'interface utilisateur interactive, et la sélection d'un ou plusieurs éléments de contenu à partir de la base de données de contenu sur la base au moins de l'objectif de patient déterminé et des informations d'utilisateur et l'affichage du ou des éléments de contenu sélectionnés à l'utilisateur sur l'interface utilisateur interactive.
Patent CA-3107612-A1 (CA)
Inventor: FRANCIS JEREMY
IPC: A61K48/00
Filed: 2019-08-30
Abstract: This disclosure provides methods for treating, ameliorating, or reversing at least one symptom of amyotrophic lateral sclerosis (ALS) in a subject by increasing the amount of neuronal aspartate in spinal cord through administration of a therapeutically effective amount of a composition comprising a nucleic acid encoding ASPA or a functional fragment thereof.