baber/WOPTO huggingface dataset:
Patent EP-3572417-A2 (EP)
Inventor: UPASANI RAVINDRA B
IPC: C07J43/00
Filed: 2012-10-12
Abstract: Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I):where R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>3'</sup>, R<sup>4</sup>, R<sup>6a</sup>, R<sup>6a</sup>, R<sup>11a</sup>, and R<sup>11b</sup>are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, insomnia, anxiety, depression, traumatic brain injury (TBI), stress, and epilepsy.
Patent EP-3624340-A2 (EP)
Inventor: GAMBUZZA MICHAEL J
IPC: H03K17/785
Filed: 2019-08-19
Abstract: A latching relay includes a supply terminal, a load terminal, first and second coupling circuits, a latch circuit, first and second transistors, and a local supply node coupled to a capacitor. In one example, the supply terminal is coupled to a supply node and the load terminal is coupled to the load. The first and second transistors control the conductivity of a drive transistor coupled to the load. A microcontroller controls the latching relay to switch the load on and off. To enable the load, the microcontroller sinks current from the supply terminal and through the first coupling circuit. While the load is enabled, the capacitor is discharged. The latching relay is operable in a refresh mode in which current is pulsed through the first coupling circuit causing capacitor to be re-charged from the supply terminal. To disable the load, the microcontroller sinks current through the second coupling circuit.
Patent EP-3787952-A2 (EP)
Inventor: HOMANN MATTHIAS
IPC: B61G1/40
Filed: 2019-04-30
Abstract: Die Erfindung betrifft ein Überwachungssystem für ein Kuppel- und/oder Dämpfungselement eines Fahrzeugs, insbesondere Schienenfahrzeugs, wobei das Kuppel- und/oder Dämpfungselement wenigstens zwei relativ zueinander entlang wenigstens einer Bewegungsrichtung bewegliche Bauteile aufweist, mit wenigstens einem Geber und wenigstens einem Sensor, die eingerichtet und angeordnet sind, die Bewegung der beiden Bauteile entlang der wenigstens einen Bewegungsrichtung zu erfassen, wobei der Geber und der Sensor signalübertragend verbunden sind, sodass der Sensor ein vom Geber erzeugtes Signal erfasst. Das erfindungsgemäße Überwachungssystem ist dadurch gekennzeichnet, dass der wenigstens eine Geber und der wenigstens eine Sensor mit konstantem Abstand zueinander positioniert sind und ein die Signalübertragung modifizierendes Element vorgesehen ist, das mit einem der Bauteile oder in Abhängigkeit der Relativbewegung der Bauteile beweglich ist, um in Abhängigkeit seiner Position das übertragene Signal zu verändern.
Patent EP-3759302-A2 (EP)
Inventor: CHERUBINI LIONELLO
IPC: E06B9/174
Filed: 2019-02-25
Abstract: A connection head (10) comprises is provided with a first body indentation (92) to accommodate a support recess (54) with a second fixed support (12b) and a second body indentation (90) flanked by said first indentation (92), divided by a body edge (94). The head further comprises an element (200) applicable to the side surface (78), having an indentation (208'). When the element (200) is applied, the indentation (208') is connected to the second body indentation (90) of the main body (76) to accommodate at least one support bracket (30, 32, 34, 36) of a first fixed support (12a).
Patent EP-3820437-A2 (EP)
Title: Injection techniques for the treatment of cellulite
Inventor: VIJAYAN SAJI
IPC: A61K8/66
Filed: 2019-07-12
Abstract: The present disclosure relates to a method of treating cellulite on a thigh or buttock in a human subject by administering an effective amount of collagenase, and then assessing the reduction in the severity of cellulite by one or more scales.
Patent EP-3893980-A2 (EP)
Inventor: STIGALL JEREMY
IPC: A61B1/005
Filed: 2019-12-11
Abstract: In an embodiment, an intraluminal device is disclosed. One embodiment of the intraluminal device comprises a flexible elongate body comprising a distal portion configured to be positioned within a body lumen of a patient and a functional device disposed at the distal portion of the flexible elongate body, the functional device configured to obtain physiological data or perform a treatment within the body lumen. The intraluminal device further comprises a stiffening member moveably disposed within and along a longitudinal length of the flexible elongate body without extending beyond a distal end of the flexible elongate body, the stiffening member being moveable during an intraluminal procedure to selectively vary a stiffness of the intraluminal device.
Patent EP-3838930-A2 (EP)
Inventor: MARISSAL DANIEL
IPC: B01J19/00
Filed: 2013-03-07
Abstract: The present invention relates to a polymerisation process, in particular to a process for the polymerisation of monomer in a reactor, which process comprises contacting a first stream comprising vapour derived from the effluent withdrawn from the reactor with a feed stream to the reactor, said first stream comprising the majority of the vaporised components of the liquid medium in the effluent withdrawn from the reactor, and wherein at least 80% by weight of the first stream is in vapour form when brought into contact with the feed stream .
Patent EP-3828721-A2 (EP)
Inventor: WU YILING
IPC: G06F16/00
Filed: 2021-03-26
Abstract: A method and apparatus for converting an undirected relationship to a directed relationship, device, storage medium and a computer program product are provided. An implementation of the method includes: determining a graph of undirected relationships between a plurality of subjects based on time characteristics of co-occurrences among the plurality of subjects; acquiring time characteristic intervals of edges between an individual subject and related subjects thereof from the graph of the undirected relationships; sorting the time characteristic intervals, and traversing the time characteristic intervals according to a sorted order, to find a target time characteristic interval not overlapping with a traversed time characteristic interval; and obtaining a directed one-way edge of the individual subject, by using a related subject corresponding to the target time characteristic interval as an end vertex of the one-way edge and using the individual subject as a start vertex of the one-way edge.
Patent EP-4036240-A2 (EP)
Inventor: GEIJSEN NIELS
IPC: A61K31/205
Filed: 2014-08-28
Abstract: The invention relates to transduction compounds, buffers and methods for introducing molecules into cells. The invention also relates to methods of treatment, pharmaceutical compositions and other uses of the transduction compounds and buffers. The invention also relates to modified cells obtainable by the transduction compounds, buffers and methods of the invention.
Patent EP-4024045-A2 (EP)
Inventor: HOFFMEYER DANIEL
IPC: G01N30/24
Filed: 2021-12-20
Abstract: A sampling needle is provided for piercing a septum of a vial containing a sample and aspirating the sample from the vial. The needle may include: a tubular core having a lumen extending therethrough and a piercing end, wherein the tubular core is formed of a bioinert material; a hollow support encircling the tubular core with the piercing end extending outwardly from the support, wherein the support is formed of a rigid material; and a bioinert coating covering a portion of the support adjacent the piercing end, wherein the tubular core and the covering isolates the support from the sample.
Patent EP-4018953-A2 (EP)
Inventor: ROSENBERG AVIGDOR
IPC: A61B90/00
Filed: 2021-12-21
Abstract: In one embodiment, a catheter alignment system includes a catheter to be inserted into a body part, and including catheter electrodes to contact tissue at respective locations within the body part, a display, and processing circuitry to receive signals provided by the catheter, assess respective levels of contact of ones of the catheter electrodes with the tissue of the body part responsively to the received signals, find a direction in which the catheter should be moved to improve at least one of the respective levels of contact of at least one of the catheter electrodes responsively to the respective levels of contact of the ones of the catheter electrodes, and render to the display a representation of the catheter responsively to the received signals, and a direction indicator indicating the direction in which the catheter should be moved responsively to the found direction.
Patent EP-4114939-A2 (EP)
Inventor: MAGUIRE ABBIE MADELINE
IPC: C12N15/11
Filed: 2021-02-26
Abstract: Among other things, the present disclosure provides oligonucleotides, compositions, and methods for preventing and/or treating various conditions, disorders or diseases. In some embodiments, provided technologies comprise nucleobase modifications, sugar modifications, internucleotidic linkage modifications and/or patterns thereof, and have improved properties, activities and/or selectivities. In some embodiments, provided technologies target MAPT. In some embodiments, the present disclosure provides MAPT oligonucleotides, compositions and methods for preventing and/or treating MAPT-associated conditions, disorders or diseases, such as Alzheimer's Disease (AD) or Frontotemporal Dementia (FTD).
Patent EP-4210972-A2 (EP)
Title: Attelage de remorque comprenant un dispositif de verrouillage
Inventor: HETFLEISCH RAIMUND
IPC: B60D1/06
Filed: 2021-10-28
Abstract: L'invention concerne un attelage de remorque pour un véhicule automobile (90), qui comprend un bras d'attelage (20), ledit bras d'attelage (20) comprenant un élément d'attelage (27) et étant monté pivotant sur un support (11) qui est fixé ou qui peut être fixé au véhicule automobile (90), entre une position d'utilisation (G) et une position de non-utilisation (N) au moyen d'un palier pivotant (30) ; le support (11) ayant une section palier pivotant (15) pour le palier pivotant (30), et un élément palier de bras d'attelage (40) qui porte le bras d'attelage (20) est monté sur le palier pivotant de manière à pouvoir pivoter autour d'un axe de pivotement (D) au moyen d'un arbre de palier (32) ; l'attelage de remorque (10) comprend un dispositif de fixation (50) pour fixer le bras d'attelage (20) au moins dans la position d'utilisation (G), et le dispositif de fixation (50) comprend au moins un élément de fixation (51) qui est monté mobile entre une position de fixation (F) dans laquelle l'élément ou les éléments de fixation (51) entrent en prise avec une zone de réception à complémentarité de forme (45) et fixent en rotation l'élément palier de bras d'attelage (40) par rapport à l'axe de pivotement (D), et une position de libération (L) dans laquelle l'élément palier de bras d'attelage (40) peut être mis en rotation par rapport à l'axe de pivotement (D). L'élément ou les éléments de fixation (51) sont disposés dans une zone extérieure autour de l'arbre de palier (32) et peuvent être déplacés par rapport à l'élément palier de bras d'attelage (40) et au support (11) entre la position de fixation (F) et la position de libération (L), et l'élément de fixation peut être actionné par un corps d'actionnement de fixation (61) qui est monté mobile dans un canal de guidage d'arbre de palier (36) qui s'étend à travers l'arbre de palier (32).
Patent EP-4243618-A2 (EP)
Inventor: RUGGERI RICCARDO
IPC: A21C9/06
Filed: 2021-11-10
Abstract: Machine (1) for making filled pasta comprising a feeding station (2), configured for feeding a layer of fresh pasta (3) and a predetermined quantity of a semi-finished food product (4) to a coupling space (5) of said machine (1), and a coupling device (17) configured for coupling the layer of fresh pasta (3) and the predetermined quantity of semi-finished food product (4). The coupling device (17) comprises at least one pair of synchronised forming rollers (18) configured to rotate, respectively, on a first and a second rotation shaft (19, 20) and defining between the m the coupling space (5). Moreover, the coupling device (17) is configured for performing, at each rotation cycle of said forming rollers 18, the production of an element of filled pasta by progressively wrapping said layer of fresh pasta 3 around the predetermined quantity of semi-finished food product 4. The coupling device (17) is configured to rotate the forming rollers (18) at a variable speed, between a maximum speed and a minimum speed, during a single rotation cycle.
Patent EP-4267678-A2 (EP)
Title: Composition adhésive thermofusible
Inventor: BELLINI CLÉMENT
IPC: C08L93/04
Filed: 2021-12-07
Abstract: La présente invention concerne une composition adhésive thermofusible comprenant : au moins un copolymère séquencé de styrène; au moins une résine donnant du collant à base biologique; et éventuellement au moins un plastifiant choisi parmi : un acide gras estérifié; et une huile de support; la composition adhésive thermofusible ayant une température de transition vitreuse supérieure à 0 °C. La présente invention concerne en outre l'utilisation de ladite composition adhésive thermofusible pour lier deux substrats et un article comprenant ladite composition adhésive thermofusible.
Patent EP-4192580-A2 (EP)
Title: Methods of treating cardiac disorders and congestive heart failure and administering aav vectors
Inventor: O'CALLAGHAN MICHAEL W
IPC: A61P9/04
Filed: 2021-08-05
Abstract: The present invention relates to methods of administration of rAAV vectors in a single administration method comprising a series of sub-administrations of sub-doses of rAAV vectors. The present invention also relates to rAAV vectors comprising cardiac-specific promoters, cardiac-cell specific promoters, multi-cell cardiac specific promoters, and elements thereof. The invention also relates to rAAV vectors, pharmaceutical compositions and uses thereof in methods for treating cardiovascular disease, heart diseases and heart failure in subjects in need thereof.
Patent EP-4079935-A2 (EP)
Title: Two-coat single cure powder coating
Inventor: DECKER OWEN
IPC: C23C24/10
Filed: 2012-12-18
Abstract: The present invention relates to methods and systems for coating metal substrates. The methods and systems include sequential application of low flow and high flow powder coatings followed by a single simultaneous cure. The methods and systems include a marker that allows coating uniformity to be monitored and assessed during application. The described methods provide coatings with optimal surface smoothness and edge coverage.
Patent EP-4104854-A2 (EP)
Inventor: JOHNSON REED F
IPC: A61K39/12
Filed: 2017-03-31
Abstract: The present disclosure provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a coronavirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a coronavirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present disclosure provides a recombinant rabies virus vector comprising a nucleotide sequence encoding at least one coronavirus immunogenic glycoprotein fragment, as well as pharmaceutical compositions comprising the vaccine vectors.
Patent EP-4124293-A2 (EP)
Inventor: DENTON STERLING
IPC: A61B5/11
Filed: 2022-07-27
Abstract: A system and method for performing range of motion measurements in an unsupervised manner. A user equipment with one or more cameras may be used with an application on the UE using the one or more cameras to measure range of motion of a user of the UE. The patient may record movement of the part of the body of interest, such as the head. The movement may be recorded in three dimensions (e.g., calculated from two dimensional coordinates of an image) and processed by the application, and the three rotational angles calculated corresponding to the difference between the final position of the head and the initial position of the head at the beginning of the recording. As a result, facial recognition is used to improve monitoring of range of motion during surgical recovery in an unsupervised environment.
Patent EP-4241852-A2 (EP)
Inventor: KIM SUNG WUK
IPC: A61P37/02
Filed: 2015-04-30
Abstract: The present disclosure relates to an isolated anti-FcRn antibody, which is an antibody binding to FcRn (stands for neonatal Fc receptor, also called FcRP, FcRB or Brambell receptor) that is a receptor with a high affinity for IgG or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method of treating and diagnosing autoimmune diseases using the antibody. The FcRn-specific antibody according to the present disclosure binds to FcRn non-competitively with IgG to reduce serum pathogenic auto-antibody levels, and thus can be used for the treatment of autoimmune diseases.
Patent EP-4279195-A2 (EP)
Inventor: ERNDT ANDREAS
IPC: B21D26/033
Filed: 2023-05-19
Abstract: The present invention relates a method of manufacturing a hair cutting device with an outer metal shell, comprising the steps of forming the outer metal shell into a desired shape and mounting functional components for performing or helping to perform a personal care treatment into and/or onto said formed outer metal shell. Said forming the outer metal shell includes a hydraulic pressure forming step.
Patent EP-4235823-A2 (EP)
Inventor: KIM YE SEUL
IPC: H01L33/22
Filed: 2016-10-14
Abstract: A light emitting diode chip includes: a first conductive type semiconductor layer disposed on a substrate; a mesa disposed on the first conductive type semiconductor layer and including an active layer and a second conductive type semiconductor layer; an insulation layer covering the first conductive type semiconductor layer and the mesa, the insulation layer including at least one first opening exposing the first conductive type semiconductor layer and a second opening disposed on the mesa; a first pad electrode disposed on the insulation layer and electrically connected to the first conductive type semiconductor layer through the first opening; and a second pad electrode disposed on the insulation layer and electrically connected to the second conductive type semiconductor layer through the second opening. The first opening of the insulation layer includes a first region covered by the first pad electrode and a second region exposed outside the first pad electrode.
Patent EP-4290823-A2 (EP)
Inventor: BUCKLEY ADRIAN
IPC: H04L65/1104
Filed: 2011-01-14
Abstract: A system for communicating a message using a second signaling protocol is disclosed. The second signaling protocol provides a session control channel between a user agent (UA) and a network node and may include, for example the l1 protocol. The system identifies a first string to be transmitted within a first message, The first message is encoded in accordance with a first signaling protocol. The system associates the first string with a first key, and stores the first string and the first key in a database. The database associates the first string and the first key. The system encodes the first key within a second message, and transmits the second message using the second signaling protocol. The first string may include a plurality of data values. The system sorts the plurality of data values into an ordering, and associates each of the plurality of data values with a key.
Patent EP-4242861-A2 (EP)
Title: Audio, video and control system implementing virtual machines
Inventor: ROSENBOOM GERRIT EIMBERTUS
IPC: G06F13/42
Filed: 2018-12-21
Abstract: The system of the present technology includes an embodiment that provides a host audio, video and control operating system configured to establish or interact with one or more virtual machines, each with a guest operating system.
Patent EP-4286840-A2 (EP)
Inventor: CLARK ALASTAIR
IPC: G01N27/623
Filed: 2019-07-26
Abstract: An ion mobility spectrometry method comprising (i) applying a voltage difference between a first electrode of an ion gate and a second electrode of the ion gate to prevent ions from leaving a reaction region of an ion mobility spectrometer;(ii) opening the ion gate to allow the ions to travel from the reaction region into a modification region between the first electrode and the second electrode;(iii) applying a radio frequency, RF, voltage between the first electrode and the second electrode to fragment the ions in the modification region to provide daughter ions;(iv) allowing the daughter ions to travel from the modification region into a drift region of the ion mobility spectrometer towards a collector;(v) closing the ion gate; and(vi) determining the time of flight of the daughter ions from the ion gate to the collector.
Patent EP-4280629-A2 (EP)
Inventor: MICHAELSEN ANDERS HJERMØ
IPC: H04R25/00
Filed: 2021-09-15
Abstract: The present disclosure relates to a wirelessly rechargeable hearing device, a charger for a wirelessly rechargeable hearing device, and a system comprising a wirelessly rechargeable hearing device and a charger for the wirelessly rechargeable hearing device.
Patent EP-0007704-A2 (EP)
Inventor: JAMES ANTHONY HUGH
IPC: A61K8/73
Filed: 1979-06-22
Abstract: A method of preparing a hair conditioning product comprising incorporating an aqueous suspension of a metal salt of pyridinethione, especially zinc pyridinethione, wherein the salt is suspended using a cathionic suspending agent, in a liquid vehicle comprising a cationic hair conditioning agent.
Patent EP-0029345-A2 (EP)
Inventor: HUME KENNETH MICHAEL
IPC: B21D5/10
Filed: 1980-11-13
Abstract: Plate is rolled to form a substantially cylindrical article on apparatus comprising a support bed for the plate (13), a rotatable mandrel (20) with a gripper (36) for engaging an edge of the plate (13), and pressure rollers (17, 18) adjacent the mandrel (20) to engage said plate. An edge of the plate (13) is engaged by gripper (36) and the mandrel (20) is rotated to advance the plate (13) past said pressure rollers (17,18) to curve the plate into a cylinder shape, the mandrel (20) and said pressure rollers (17, 18) are relatively movable to create a force on the advancing plate (13) at least during the final stages of rolling to prevent relative movement of the plate (13) and mandrel (20).