baber/WOPTO huggingface dataset:
Patent AU-2016277685-B2 (AU)
Title: Modified proteins and peptides
Inventor: ASHMAN CLAIRE
IPC: C07K16/00
Filed: 2016-12-22
Granted: 2019-03-28
Abstract: The present invention relates to modified proteins and peptides that have reduced ability to bind to pre-existing antibodies. Such modified protein/peptide molecules can comprise C-terminal additions, extensions or tags and/or certain amino acid substitutions. Such modified molecules (e.g. 5 fusions and conjugates) comprise proteins, peptides, antigen binding molecules, antibodies or antibody fragments such as single variable domains e.g. human immunoglobulin (antibody) single variable domains, and also single variable domains derived from non-human sources such as a llama or camel, e.g. a VHH including a nanobody TM (described in e.g. WO 94/04678 and WO 95/04079 inter alia). The invention further relates to uses, formulations, compositions comprising such 0 modified C terminally extended and/or amino acid substituted molecules and also to methods of production and expression of these molecules.
Patent AU-2016278742-B2 (AU)
Title: Device having monitored device cooling
Inventor: LANZ BERNHARD
IPC: B23K9/007
Filed: 2016-06-13
Granted: 2018-12-06
Abstract: The invention relates to a device (1) for providing electric power, wherein the device (1) comprises: at least one integrated temperature sensor (3-1, 3-2), which measures an operating temperature profile of at least one component (2-1, 2-2) of the device (1), and a monitoring unit (5), which monitors the operating state of a device cooling of the device (1) on the basis of the at least one measured operating temperature profile and of the set power.
Patent AU-2016299438-B2 (AU)
Title: Method for deaerating a dialyser
Inventor: KLÖFFEL PETER
IPC: A61M1/36
Filed: 2016-07-27
Granted: 2021-04-08
Abstract: The invention relates to a method for deaerating a dialyser comprising a dialysate chamber, a blood chamber, and a semi-permeable dialyser membrane which separates these two chambers, wherein, in order to remove entrapped air present on the dialysate chamber-side surface of the membrane, an excess pressure in relation to the blood chamber is produced in the dialysate chamber once said dialysate chamber has been filled and before the blood chamber is filled.
Patent AU-2016317088-B2 (AU)
Title: Rate and place of stimulation matched to instantaneous frequency
Inventor: SCHLEICH PETER
IPC: H04R25/00
Filed: 2016-07-06
Granted: 2019-07-18
Abstract: A signal processing arrangement generates electrical stimulation signals to stimulation contacts in an implanted cochlear implant array. An input sound signal is decomposed into dominant psychophysically relevant frequency components, with each frequency component changing over time in frequency and level. Each frequency component is coded as a patient-specific, frequency-specific function of stimulation location, rate, and level to produce a sequence of requested stimulation events having an instantaneous frequency and level. And the electrical stimulation signals are generated from the requested stimulation events for delivery by the stimulation contacts to adjacent auditory neural tissue.
Patent AU-2016325487-B2 (AU)
Title: Conversion of biomass into methane
Inventor: MEHTA DHAIRYA DILIP
IPC: C07C1/20
Filed: 2016-09-23
Granted: 2019-04-11
Abstract: The present invention provides a process for producing methane from a biomass, biomass-containing and/or biomass-derived feedstock, said process comprising the steps of: a) providing in a hydropyrolysis reactor vessel a 5 hydropyrolysis catalyst composition, said composition comprising one or more active metals supported on an oxide-based support, said one or more active metals comprising at least one of cobalt and nickel and said one or more active metals being present in total in an amount 10 in the range of from 2 to 75wt% based on the overall weight of the catalyst composition; b) contacting the feedstock with said hydropyrolysis catalyst composition and molecular hydrogen in said hydropyrolysis reactor vessel at a temperature in the 15 range of from 300 to 600°C and a pressure in the range of from 0.50 to 7.50MPa, to produce a first product stream comprising char, catalyst fines and gases comprising hydrogen and hydrocarbons, of which hydrocarbons at least 70wt% is methane and, optionally, CO and CO2; and 20 c) removing said char and catalyst fines from said first product stream.
Patent AU-2016332560-B2 (AU)
Title: Hybrid continuous indexing tamper vehicle
Inventor: MAURICE PETER ROBERT
IPC: E01B35/00
Filed: 2016-09-26
Granted: 2021-07-29
Abstract: The present disclosure generally relates to an improved tamping operation where a rail tamping machine advances at different speeds during different stages of tamping and workhead assembly operation. The workhead assembly is also capable of moving longitudinally relative to the rail tamping machine frame when it is detected that the rail tamping machine is at an appropriate distance from a reference point. Related methods of tamping are also described.
Patent AU-2016339049-B2 (AU)
Title: Polymer blends
Inventor: REBIH FATIMA
IPC: C08L23/12
Filed: 2016-10-14
Granted: 2021-05-06
Abstract: Compatibilizer for a polymer blend, use of the compatabilizer in a polymer, a polymer blend comprising the compatabilizer, an article formed from the polymer blend, and methods for making the compatabilizer, polymer blend and article.
Patent AU-2016344030-B2 (AU)
Title: CpG reduced factor VIII variants, compositions and methods and uses for treatment of hemostasis disorders
Inventor: ANGUELA XAVIER
IPC: C12N15/864
Filed: 2016-10-31
Granted: 2021-05-06
Abstract: CpG reduced nucleic acid variants encoding FVIII protein and methods of use thereof are disclosed. In particular embodiments, CpG reduced nucleic acid variants encoding FVIII are expressed more efficiently by cells, are secreted at increased levels by cells over wild-type Factor VIII proteins, exhibit enhanced expression and/or activity over wild-type Factor VIII proteins or are packaged more efficiently into viral vectors.
Patent AU-2016344747-B2 (AU)
Title: Compositions and their use in food preservation
Inventor: MENEGHIN MARTINO
IPC: A23L3/3472
Filed: 2016-10-27
Granted: 2020-12-10
Abstract: The present invention relates to preservative compositions comprising at least two extracts selected from oak extract, grape seed extract and green tea extract. Said compositions are useful in the preservation of foods liable to lipid peroxidation.
Patent AU-2016379181-B2 (AU)
Title: Methods for preparing dry cross-linked tissue
Inventor: WANG WEI
IPC: A61L27/36
Filed: 2016-12-19
Granted: 2019-09-26
Abstract: A method of preparing dry cross-linked biological tissue. A processing solution is prepared that contains a cross-linking agent and an organic water-soluble liquid. Biological tissue is immersed in the processing solution for an effective period of time to substantially displace water from the biological tissue and substantially cross-link the biological tissue to form dry cross-linked biological tissue.
Patent AU-2016384357-B2 (AU)
Title: Transport and storage container of plastic for a filling material
Inventor: RICHTER BODO
IPC: H05F1/00
Filed: 2016-12-29
Granted: 2021-10-21
Abstract: The invention relates to a transport and storage container of plastic for a filling material, having an inner container (14) of polyethylene which is produced in the blow-molding method and which has a single-layer wall structure. The inner container (14) is accommodated by an outer container, which is open at the top and which contains at least one layer of electrically conductive plastic. The outer lateral surface of the inner container (14) is wrapped with an electrically dissipative flexible material (16), wherein at least one electrically conductive tab (18) covers at least part of the top side of the inner container (14).
Patent AU-2017203824-B2 (AU)
Title: Antimicrobial Sacrificial Floor Coating Systems
Inventor: KAUFOLD REBECCA S
IPC: C09D133/04
Filed: 2017-06-06
Granted: 2021-10-21
Abstract: Disclosed are antimicrobial sacrificial floor coatings systems including an 
antimicrobial sacrificial floor coating composition capable of reducing and/or preventing 
gram positive and gram negative bacterial growth on floors. Also disclosed is an antimicrobial 
5 sacrificial floor coating remover being readily capable of removing the antimicrobial 
sacrificial floor coating as desired from previously treated flooring surfaces. In certain 
aspects, the antimicrobial sacrificial floor coatings can include a nonionic acrylic polymer; a 
nonionic wax; and a cationic alkyl biguanide or salt thereof. The antimicrobial sacrificial floor 
coating may further include a cationic wax that further stabilizes the system during storage, 
0 application, and/or post-application to a floor surface. The antimicrobial sacrificial floor 
coating composition has a pH of less than 7 while exhibiting continuous antimicrobial 
properties from full cure on a floor surface up to 1 year post-application to the floor surface at 
a minimum contact time of 1 hour.  
5 
Page 60 of 60
Patent AU-2017204000-B2 (AU)
Title: Powder Container and Image Forming Apparatus
Inventor: KIKUCHI KENJI
IPC: G03G15/08
Filed: 2017-06-14
Granted: 2019-01-31
Abstract: Abstract A powder container is disclosed. In one aspect, the powder container comprises: an opening at one end of the powder 5 container in a longitudinal direction of the powder container; a container gear to rotate at least a portion of the powder container; an extension extending along the longitudinal direction of the powder container, the extension including at least one surface to guide the 10 powder container. The powder container further comprises a protrusion that protrudes in a radially outward direction away from a center longitudinal axis of the powder container and extends in the longitudinal direction of the powder container, the protrusion being disposed downstream 15 of the extension, relative to an attachment direction of the powder container and being disposed between the opening and the extension, relative to the longitudinal direction of the powder container. 0)L
Patent AU-2017204111-B2 (AU)
Title: Providing priming cues to a user of an electronic device
Inventor: MOUSSETTE CAMILLE
IPC: A61B5/16
Filed: 2017-06-16
Granted: 2019-01-31
Abstract: An electronic device can output a priming cue prior to outputting an alert on the electronic device. A priming cue can be a haptic priming cue, a visual priming cue, an audio priming cue, or various combinations of these priming cues. The priming cue can be perceived by a user either consciously or subconsciously and can increase a user's perceptual state for the alert.
Patent AU-2017209742-B2 (AU)
Title: Differentiation induction from human pluripotent stem cells into hypothalamic neurons
Inventor: SUGA HIDETAKA
IPC: C12N5/0793
Filed: 2017-01-18
Granted: 2022-12-01
Abstract: Provided is a method for efficiently inducing differentiation from human pluripotent stem cells into hypothalamic neurons. Also provided is a method for constructing a cellular structure that integrates pituitary tissue and hypothalamic tissue from human pluripotent stem cells. A cellular structure including hypothalamic tissue is obtained by a method including a step for suspension culturing human pluripotent stem cell spheroids in a medium including a low concentration of an osteogenic factor signaling pathway activator and a low concentration of a substance capable of acting on the Shh signaling pathway, and a step for also suspension culturing the cell spheroids obtained in that step in a medium including a low concentration of a substance capable of acting on the Shh signaling pathway. A cellular structure including hypothalamic tissue and pituitary tissue is also obtained by a method including a step for suspension culturing human pluripotent stem cell spheroids in a medium including an osteogenic factor signaling pathway activator and a substance capable of acting on the Shh signaling pathway, a step for also suspension culturing the cell spheroids formed in that step in a medium including an osteogenic factor signaling pathway activator and a substance capable of acting on the Shh signaling pathway, and a step for suspension culturing the cell spheroids obtained in that step in a medium suitable for simultaneous pituitary and hypothalamic induction .
Patent AU-2017213177-B2 (AU)
Title: Therapeutic compounds
Inventor: MARTIN BARRIE
IPC: A61K31/506
Filed: 2017-01-30
Granted: 2020-10-08
Abstract: The present invention relates to compounds that are antagonists of the orexin-1 receptor. The compounds have the structural formula (I) defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with orexin-1 receptor activity.
Patent AU-2017232554-B2 (AU)
Title: Powders and tablets comprising omega-3 fatty acid derivatives and methods for their production
Inventor: LIEN VESTLAND TINA
IPC: A23P10/47
Filed: 2017-03-15
Granted: 2020-05-14
Abstract: The present invention relates to methods of using surface active compounds(s) in the preparation process for powders comprising beta-cyclodextrin and omega-3 fatty acids and derivatives thereof and to the dry powders and tablets comprising surface active compounds(s) preferably diglycerides, beta-cyclodextrin and omega-3 fatty acids and derivatives thereof.
Patent AU-2017248416-B2 (AU)
Title: Self-orienting syringe and syringe to-injector interface
Inventor: COWAN KEVIN P
IPC: A61M5/145
Filed: 2017-10-16
Granted: 2019-12-05
Abstract: A syringe comprising: a barrel having a distal end, a proximal end, and a sidewall extending substantially circumferentially between the distal end and the proximal end along a longitudinal axis; and at least one engagement member protruding from a terminal portion of the sidewall in a proximal direction along the longitudinal axis, the at least one engagement member tapering axially in a direction from the distal end toward the proximal end, wherein the at least one engagement member is configured for engagement with a locking mechanism of a fluid injector to releasably position the syringe with a syringe port of the fluid injector, and wherein a taper of the at least one engagement member is configured to rotationally guide the syringe into alignment with the locking mechanism and axially eject the syringe upon rotation of the syringe. 22 , 12-, 41 4 2 210 -w2 ldgw- 32 \ / '39A 18 -- -20
Patent AU-2017251704-B2 (AU)
Title: Beta-substituted beta-amino acids and analogs as chemotherapeutic agents
Inventor: JANDELEIT BERND
IPC: A61P35/00
Filed: 2017-10-24
Granted: 2019-03-07
Abstract: Abstract p-Substituted p-amino acids, p-substituted p-amino acid derivatives, and p-substituted p-amino acid analogs and (bio)isosteres and their use as chemotherapeutic agents are disclosed. The p-substituted p-amino acid derivatives and p-substituted p-amino acid analogs and (bio)isosteres are selective LAT1/4F2hc substrates and exhibit rapid uptake and retention in tumors expressing the LAT1/4F2hc transporter. Methods of synthesizing the P-substituted p-amino acid derivatives and p-substituted p-amino acid analogs and methods of using the compounds for treating cancer are also disclosed. The p-substituted p-amino acid derivatives and p-substituted p-amino acid analogs exhibit selective uptake in tumor cells expressing the LAT1/4F2hc transporter and accumulate in cancerous cells when administered to a subject in vivo. The P-substituted p-amino acid derivatives and p-substituted p-amino acid analogs and (bio)isosteres exhibit cytotoxicity toward several tumor types.
Patent AU-2017254352-B2 (AU)
Title: Safety system, method and computer program for remotely controlled work vehicles
Inventor: IDBRANT MARCUS
IPC: G05D1/02
Filed: 2017-04-20
Granted: 2021-07-08
Abstract: The present disclosure relates to a safety system (100) for a remotely operated work vehicle (110). The safety system (100) works by continuously establishing a spatial relationship between the work vehicle (110) and a wireless remote control unit (130), wherein at least part of the information needed to establish the spatial relationship is carried as data in signals. The established spatial relationship is then used to control the work vehicle (110).
Patent AU-2017263457-B2 (AU)
Title: Vinylogous phenethylamines as neurotransmitter releasers
Inventor: BLOUGH BRUCE
IPC: A61K31/137
Filed: 2017-05-11
Granted: 2021-07-08
Abstract: The disclosure provides monoamine neurotransmitter releaser and/or monoamine uptake inhibitor compounds having biogenic amine transporter activity but lacking substantial activity at 5-HT
Patent AU-2017278462-B2 (AU)
Title: System providing a shared environment
Inventor: KEEFE JOHN ALEXANDER
IPC: A63F13/35
Filed: 2017-06-05
Granted: 2022-09-15
Abstract: The invention relates to a system (10) enabling at least one user (20) to engage with multiple devices (50) in a shared environment in a time (t) dependent manner. More particularly the system has been designed to facilitate interaction between different users, on different devices and different platforms (60). This is very different to systems allowing different players, playing the same game on different platforms to interact. Thus, the present Invention may allow software developers to work on given different areas of development and come together remotely and interact to experience a fuller or richer experience, it also enables applications in a wide variety of areas. The system (10), enables one or more users (20-1, 20-2) to engage with at least two devices (50a-e), which operate on different platforms (60a-e), In a time (t) dependent manner. It comprises a data management apparatus (DMA) (100) which will receive and collate data inputs (40-1, 40-2, 40-3) from the devices (50-1; 50-2, 50-3) providing experiences (30-1, 30-2, 30-3). and generate a merged standardized data output (70) which is relayed (92) back to the one or more users (20-1, 20-2) and their devices (50) where it is, demerged such that each device can access experiences for which it is enabled. The system (10) continuously monitors the one or more users devices (50a-e) and platforms (60a-e), determines if they are supported by the system (10), and will only attempt to read data (40-1, 40-2 40-3 from a device (50a-e) and platform (60a-e) supported by the system (10).
Patent AU-2017298984-B2 (AU)
Title: Methods of purifying Fc-containing proteins
Inventor: KAWOOYA JOHN K
IPC: C07K1/22
Filed: 2017-07-21
Granted: 2023-08-31
Abstract: The present invention relates to methods of purifying proteins containing Fc regions, such as antibodies and Fc fusion proteins. In particular, the present invention relates to a purification method resulting in reduced levels of aggregate protein comprising adsorbing an Fc region-containing protein to a temperature-responsive protein A resin and eluting the protein from the resin at a temperature below 35 C with an elution buffer comprising a chaotropic agent, a sugar alcohol, and at least one amino acid. Methods of separating fully assembled antibodies from half antibody forms thereof using the elution buffer are also described.
Patent AU-2017301936-B2 (AU)
Title: Enhanced process for selective salt recovery from wastewater and brines
Inventor: BESSENET SEBASTIEN
IPC: C01D5/16
Filed: 2017-07-27
Granted: 2019-11-14
Abstract: A process for treating wastewater or waste brines that include sodium, sulfate and chloride ions. In one embodiment, the waste brine is concentrated in a brine concentration unit (24) and thereafter directed to a Mirabilite crystallizer (28) that produces hydrated sulfate salt crystals and a first solution (29). The hydrated crystals are melted in a mirabilite melter (30) to form an aqueous sulfate solution that is directed to a sodium sulfate crystallizer (32) which produces sodium sulfate salt crystals. The first solution (29) produced by the Mirabilite crystallizer (28) is directed to a nanofiltration device (36) which produces a permeate stream and a reject stream (31) containing sulfate removed by the nanofiltration device (36). The permeate stream is directed to a sodium chloride crystallizer (40) that produces sodium chloride salt crystals. The reject stream (31) is recycled to the Mirabilite crystallizer (28). The waste brine may be produced by a coal to chemical or coal to liquid process.
Patent AU-2017316684-B2 (AU)
Title: System for neuromodulation comprising electrodes and means for determining an electrode fractionalization
Inventor: ZHANG TIANHE
IPC: A61N1/36
Filed: 2017-08-23
Granted: 2020-05-14
Abstract: A system includes electrodes on at least one lead (2280) configured to be operationally positioned for use in modulating a volume of neural tissue, a neural modulation generator configured to deliver energy using at least some electrodes to modulate the volume of neural tissue and a programming system configured to program a modulation parameter set, including determine electrode fractionalizations for the electrodes based on a target multipole. The modulation parameter set may include the electrode fractionalizations. The neural modulation generator may be configured to use the modulation parameter set to provide a linear electric field over the volume of tissue.
Patent AU-2017326133-B2 (AU)
Title: Pushchair accessory, and a transport assembly comprising a pushchair and such an accessory
Inventor: CHAUDEURGE JEAN-MICHEL
IPC: B62B9/28
Filed: 2017-06-19
Granted: 2022-10-13
Abstract: This accessory (20), such as a platform for a pushchair, comprises a frame (21), which is provided with at least one wheel (22), and a device (23) for reversibly connecting to the frame (11) of a pushchair (10), this device being supported by the frame. In order for this accessory to be able to be firmly, effectively, aesthetically and very easily connected to the pushchair, the device (23) is suitable for being attached between a left-hand upright (16G) and a right-hand upright (16D) of the pushchair (10), which respectively belong to a left-hand rear portion (11.1G) and to a right-hand rear portion (11.1D) of the frame (11) of the pushchair, which are parallel to each other and have respective faces, facing each other, in which a first female housing (18G) and a second female housing (18D) are respectively hollowed out, the device comprising: - first and second male elements that can move relative to the frame between a connection position, in which the first and second male elements are respectively received in a complementary manner in the first and second female housings when the device is attached between the left-hand and right-hand uprights of the pushchair, and a disconnection position, in which the first and second male elements are outside the first and second housings; and - a mechanism for activating the first and second male elements, this mechanism being suitable for: - jointly moving, through the action of only one hand of a user, the first and second male elements from their connection position to their disconnection position; and - automatically returning, in the absence of any action, the first and second male elements from their disconnection position to their connection position.