baber/WOPTO huggingface dataset:
Patent CA-2475953-A1 (CA)
Inventor: GALLAGHER PATRICIA E
IPC: C07K7/14
Filed: 2003-02-27
Abstract: La présente invention a trait à l'utilisation de peptide de l'angiotensine (1-7) en tant que traitement anticancéreux. Ainsi, dans un mode de réalisation, la présente invention comporte une composition pour l'inhibition de la croissance des cellules cancéreuses chez un individu comprenant une quantité pharmaceutiquement efficace d'un agoniste du récepteur de l'angiotensine (1-7) en vue de l'inhibition de la croissance ou la prolifération de cellules cancéreuses. L'application d'une quantité pharmaceutiquement efficace de l'angiotensine (1-7) ou de l'agoniste du récepteur de l'angiotensine (1-7) est associée à une expression accrue des gènes impliqués dans la suppression tumorale, l'apoptose et/ou l'inhibition de cycle cellulaire, et une réduction de l'expression d'oncogènes connus, des protéinekinases, et/ou de gènes de développement du cycle cellulaire. Les cancers traités par l'utilisation de ces procédés et compositions de l'invention comprennent les cancers présentant un récepteur de l'angiotensine (1-7), comprenant, mais de manière non exclusive, le cancer du sein et le cancer pulmonaire.
Patent CA-2477823-A1 (CA)
Title: Access guard for distributor modules
Inventor: NIJHUIS ANTONY
IPC: H01R9/24
Filed: 2003-02-21
Abstract: Disclosed is an access guard device for securing access to at least two distribution modules used in telecommunication and data technology. Each distribution module is provided with terminal sides comprising at least one system side and at least one subscriber side. Each terminal side is provided with at least one row of insulation displacement contact elements. The distribution modules are mounted on a mounting frame. At least one access to the system sides is secured by at least one locking device and at least one access to the subscriber sides is secured by at least one locking device. The access lock to the subscriber side of at least one distribution module can be unlocked independently of the other distribution modules.
Patent CA-2479572-A1 (CA)
Inventor: NEGRE CYRIL
IPC: F02G5/00
Filed: 2003-03-21
Abstract: Groupe de cogénération utilisant préférentiellement un groupe motocompresseur-motoalternateur équipé d'un réchauffeur thermique fonctionnant d'une manière autonome, en prélevant de l'air comprimé fourni par un ou plusieurs des étages de compression, qui est ensuite réchauffé pour accroître sa température et/ou sa pression, puis réinjecté dans les chambres d'expansion du moteur pour produire le temps moteur, dans lequel le chauffage de l'habitation est utilisé en tant que dispositif de réchauffage de l'air comprimé et pouvant être utilisé en réseau de proximité où chaque maison d'un groupe d'habitations (40, 40A,...) est équipée de tels groupes, reliés entre eux (41) et commandés par une centrale de gestion d'énergie (42) pour permettre de fournir l'électricité à chacune des habitations à partir d'un ou de plusieurs groupes qui pourront être activés successivement et/ou alternativement en fonction des besoins globalisés de l'ensemble des habitations du réseau.
Patent CA-2480571-A1 (CA)
Title: Selective, catalytic, thermal functionalization of secondary or aromatic c-h cyclic hydrocarbon bonds
Inventor: CHEN HUIYUAN
IPC: C07F5/02
Filed: 2001-03-01
Abstract: A catalytic process having more than 50 turnovers comprises thermally activating a catalysis, in the presence of a functionalizing reagent and a cyclic hydrocarbon comprising an aromatic compound or a cycloparaffin compound lacking primary C-H bonds. The catalyst comprises (a) a source of a transition metal; (b) a source of a 3 to 8, cyclic or non-cyclic, aromatic or non-aromatic, neutral, cationic or anionic, substituted or unsubstituted, electron donor moiety which does not dissociate under thermal reaction conditions; a.nd (c) a source of ligands capable of formally donating an electron pair to the transition metal (a) and which dissociate thermally; and wherein said functionalizing reagent comprises a source of B, C, N, O, Si, P, S, Ge, As, Al, or Se.
Patent CA-2481415-A1 (CA)
Title: Method and device for holding reclosable thermoplastic slider bags
Inventor: STANLEY DANIEL WARWICK JR
IPC: B65D33/25
Filed: 2003-04-02
Abstract: A holding device(20) for thermoplastic bags(50) utilizes bags having side panels(52) and a reclosable seal at one end thereof, the reclosable seal comprising a pair of opposed interlocking closure strips(56) and a slider(58) for opening and closing the closure strips(56). The holding device(20) comprises a support surface and a pair of elongate holding members (23,24) each having a proximal portion(33) adjacent the support surface and a distal portion(34) wherein the holding members define a channel(36) therebetween. The channel(36) has a first section(25) for receiving and enclosing a portion of the slider and a second section(26) for receiving only the closure strips(56) but not the slider(58). The channel(36) further has a slot(30) formed by the distal portions(34) of the holding members (23,24) wherein the slot(30) has a width sufficient to allow the side panels(52) of the thermoplastic bag(50) to enter the slot(30) but prevent passage of the closure strips(56) through the slot (30) .
Patent CA-2482598-A1 (CA)
Title: Peptide inhibitors of protein kinase c
Inventor: MOCHLY-ROSEN DARIA
IPC: A61K38/08
Filed: 2003-04-22
Abstract: PKC V5 isozyme-specific peptides are described. The sequences and compositio ns comprising the sequences are useful for treating diseases states associated with the PKC isozyme from which they are respectively derived. Methods of treatment, pharmaceutical formulations and methods of identifying compounds that mimic the activity of the peptides are also described.
Patent CA-2484828-A1 (CA)
Inventor: JOHNSON KIRK
IPC: A61F2/82
Filed: 2004-10-15
Abstract: A stent or other intraluminal medical device may be constructed utilizi ng multiple, individual, independent, self-expanding stent segments which are designed to interlock when constrained within a delivery sheath and uncouple upon deployment. The individual segments are releasably connected by a series of bridging elements and receptacles.
Patent CA-2488591-A1 (CA)
Title: Bearing material
Inventor: DUONG LOC QUANG
IPC: F16C33/14
Filed: 2004-11-30
Abstract: A journal bearing system includes a bushing and a journal pin within the bushing. At least one of the bushing and journal pin has an engagement surface with an engagement length comprising a base material and a solid lubricant. A concentration of the solid lubricant varies along the engagement length.
Patent CA-2491285-A1 (CA)
Title: Telecommunications device
Inventor: BROWN GORDON
IPC: H04M1/7243
Filed: 2003-06-27
Abstract: A telecommunications device (100) comprises a first connector (146, 146a, 150), a second data connector (170, 172) and a power supply (169). The first connector (146, 146a, 150) is arranged to communicate with a portable electronic apparatus (500). The second connector (170, 172) is arranged to communicate with a telecommunications network (173) such that a data connection is made between the portable apparatus (500) and the network. The power supply (169) is arranged to power the, or a, portable electronic apparatus (500).
Patent CA-2496324-A1 (CA)
Inventor: BETTACCHINI MARCELLO
IPC: B27C1/14
Filed: 2005-02-07
Abstract: A planer and thicknesser comprising a frame having a passage way which extends through the frame from one aperture in a wall of the frame to another aperture in a wall of the frame; an upper table having a front and rear sections mounted on the frame in such a manner in order to form a slot between the front and rear sections of the upper table; a cutting drum rotatably mounted within the frame such that an upper lengthwise section of the periphery of the cutting drum projects upwardly through the slot and a lower lengthwise section of the periphery of the cutting drum projects downwardly into the passage way; a lower table, substantially parallel to the upper table, mounted either within the passageway or forms the base of the passageway, below the cutting; a cover mounted above the upper table capable of being moved from a first position where it is adjacent the upper table and covers the lengthwise section of the periphery of the cutting drum which projects upwardly through the slot to a second position where it is above and away from the upper table characterised in that the cover can be moved perpendicularly relative to the plane of the upper table from the first position to the second position.
Patent CA-2497625-A1 (CA)
Inventor: RAMU ASHOK T
IPC: G06F17/00
Filed: 2003-09-10
Abstract: The present invention relates to a computer primary data storage system (46) that integrates the functionality of file backup (56) and remote replication (76) to provide an integrated storage system that protects its data from loss related to system or network failures or the physical loss of a data center.
Patent CA-2497907-A1 (CA)
Inventor: VELAZQUEZ HERB F
IPC: A61F2/00
Filed: 2003-05-20
Abstract: La présente invention a trait à un dispositif pour l'incontinence urinaire. Le dispositif est un dispositif vaginal souple comprenant une portion de base reliant une portion proximale d'une première branche et une portion proximale d'une deuxième branche pour constituer un configuration globalement en forme de C. Le dispositif comprend également un organe qui est un organe d'insertion, un organe de retrait ou les deux.
Patent CA-2498388-A1 (CA)
Inventor: BOISVERT ELISE
IPC: F21V21/096
Filed: 2005-02-04
Abstract: A magnetic base flashlight holder provides for the hands free holding of a flashlight enabling the user to perform any task using both hands freely while keeping the area of interest illuminated. The body of the base having a snaked shape contains two permanent fixed magnets under the base itself. The center of the base contains an exterior centered member having a first end and an opposite end. The member is a flexible neck providing rotation having the first end attached to the center of the base and the extended opposite end of the flexible neck having an open housing. The open housing contain a magnet which is mounted centrally into the housing and on the surface of the housing for receiving a magnetic object such as; a flashlight having a magnetic end.
Patent CA-2498868-A1 (CA)
Title: Power toothbrush
Inventor: GOLDFINE HENRY S
IPC: A46B17/08
Filed: 2003-09-17
Abstract: A power operated toothbrush comprises a hollow handle (12) and a head (14) mounted to the handle. A power drive assembly (16, 18, 20) is in the handle operatively connected to a movable section (24) in the head (14) for moving that section. Cleaning elements (30) extend outwardly from the movable section. A bumper (40) is secured to the peripheral side wall (42) of the he ad (14). The bumper is made of a soft yieldable material to prevent injury to t he teeth and gums and to act as a cushion to minimize high intensity vibration and to deaden sound which would result during use of the power operated toothbrush.
Patent CA-2500826-A1 (CA)
Inventor: VAN DE GEER BERNARDUS W G
IPC: B60N2/235
Filed: 2005-03-15
Abstract: A rotary seat recliner mechanism is provided including an inner gear disc, an outer gear disc, and a center gear disc. The inner gear disc has a first toothed recess. The outer gear disc has a second toothed recess. The center gear disc is supported for eccentric rotation between the inner and outer gear discs. The center gear disc includes a first gear portion and a second gear portion. The first gear portion meshingly engages the first toothed recess. The second gear portion meshingly engages the second toothed recess.
Patent CA-2502888-A1 (CA)
Inventor: LANDAU SERGIO
IPC: A61M5/28
Filed: 2003-08-28
Abstract: A method of manufacture for a drug cartridge assembly. The method includes providing a drug cartridge, providing a nozzle sub-assembly, and sterilizing the drug cartridge and nozzle sub-assembly. The method further includes assembling the drug cartridge and nozzle sub-assembly together in a configuration that enables ejection of liquid out of the drug cartridge through the nozzle sub-assembly. The method further includes filling the drug cartridge with a liquid, such as an injectable drug. The method may include separate sterilization of the drug cartridge and nozzle sub-assembly, using different sterilization processes. Portions of the method may be performed prior to sterilization within a first cleanroom, with subsequent steps being performed in a second cleanroom having a substantially lower particulate-per-volume rating than the first cleanroom.
Patent CA-2506103-A1 (CA)
Inventor: CHOPARD FABRICE
IPC: B01F5/06
Filed: 2003-11-07
Abstract: Cette invention se rapporte à un insert pour chambre de réacteur, ayant t une section transversale essentiellement carrée. La chambre comporte une entrée à l'une de ses extrémités et une sortie à l'autre extrémité, et au moins l'une des parois de la chambre du réacteur est constituée d'un matériau thermoconducteur ou d'une membrane. L'insert comprend un certain nombre d'unités qui sont disposées en rangées et qui, associées aux parois de la chambre, définissent un canal pour un fluide. Le canal part d'un premier côté de la chambre et passe par un second côté de la chambre et revient au premier côté, aller et retour plusieurs fois. Les unités sont disposées pour que le fluide s'écoule de force entre elles selon un trajet en serpentin. Cette invention se rapporte en outre à un réacteur qui comprend au moins une chambre de réacteur contenant un tel insert de direction d'écoulement.
Patent CA-2506157-A1 (CA)
Title: Treatment of diabetes
Inventor: SEELEY TODD W
IPC: A61K31/70
Filed: 2003-12-05
Abstract: The present invention relates to methods and compounds for regulating glucose metabolism, achieving glucose homeostasis, and decreasing blood glucose levels. Methods and compounds for treating or preventing diabetes, hyperglycemia, and disorders and conditions associated with altered or impaired glucose metabolism are also provided.
Patent CA-2509314-A1 (CA)
Title: Resin compositions
Inventor: YEH MAO-JUNG
IPC: C08L33/12
Filed: 2005-06-08
Abstract: The invention pertains to a resin composition capable of absorbing UV light, comprising inorganic particulates and a resin containing as a polymerized unit an acrylate monomer. The composition of the invention can be formulated into a coating for a substrate so as to impart UV resistance and good weatherability to the coated substrate.
Patent CA-2511763-A1 (CA)
Inventor: PROTTER ANDREW A
IPC: A61K31/425
Filed: 2003-12-05
Abstract: L'invention a trait à des méthodes destinées à traiter le diabète par l'administration d'inhibiteurs de la protéine kinase activée par des mitogènes p38. L'invention se rapporte également à des méthodes permettant de réduire la glycémie chez des diabétiques, par l'administration d'inhibiteurs de la protéine kinase activée par des mitogènes p38.
Patent CA-2513717-A1 (CA)
Title: Novel use of mifepristone and derivatives thereof as hedgehog protein signalling pathway modulators and applications of same
Inventor: RUAT MARTIAL
IPC: A61K31/56
Filed: 2004-01-22
Abstract: The use of estra-4,9-dien-3-one derivative steroid compounds (including D-homo-steroid analogs) (I) (i.e. mifepristone (Ia) and related compounds) as medicaments for modulating the hedgehog protein signaling pathway, and treating disorders involving tissue dysfunction associated with deregulation of the pathway, is new.  The use of steroid or D-homo-steroid compounds of formula (I) or their salts is claimed in the production of medicaments for modulating (i.e. activating or inhibiting) the hedgehog protein signaling pathway and treating disorders involving tissue dysfunction associated with deregulation of the pathway.  R1  =  1-18C organic group, containing at least one N, P or Si atom and bonded to the steroid nucleus via C;  R2  =  1-8C hydrocarbyl;  X  =  tri- or tetramethylene group (or unsaturated equivalent), completing a 5- or 6-membered, saturated or unsaturated ring, optionally substituted by one or more of Q1 (optionally substituted by one or more groups Q2) and/or Q2;  Q1  =  alkyl, alkenyl, aryl or aralkyl or up to 12C;  Q2  =  OH, CHO, COX1, OX2, COOX3, OCOX4, halo, SH, SX5, SOX6 or SO2X7;  X1 - X7  =  1-8C alkyl, 2-8C alkenyl, 2-8C alkynyl, 6-15C aryl or 6-15C aralkyl;  C = A = oxo (optionally in ketal-blocked form), CH-OH, CH-OY1, 'alkylcarboxylate -C(=H)(=O)-C(=O)-Y2' (sic), C=NOY3 or CH2;  Y1 - Y3  =  1-8C alkyl or 7-15C aralkyl;  A1 + A2  =  additional C-C bond or -O- (epoxide).
Patent CA-2516236-A1 (CA)
Title: Antibodies to c-met for the treatment of cancers
Inventor: EVANS MICHELLE L
IPC: C07K16/30
Filed: 2004-02-11
Abstract: Antibodies specific for c-Met, a protein tyrosine kinase whose ligand is hepatocyte growth factor (HGF), are provided. The antibodies and fragments 5 thereof may block binding of HGF to c-Met. Antagonist antibodies can be employed to block binding of HGF to c-Met or substantially inhibit c-Met activation. The c-Met antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treating cancer, pathological liver conditions, and ophthalmic diseases using the c-Met 10 antibodies are also provided.
Patent CA-2516295-A1 (CA)
Inventor: SHARROW JAMES S
IPC: A61M25/01
Filed: 2004-02-24
Abstract: A guidewire can include a shaft or core wire that has a distal section configured for access to a vascular treatment site and a proximal section configured for intervention at a vascular treatment site. At least a portion of the distal section of the shaft or core wire can have a diameter that is greater than a diameter of the proximal section.
Patent CA-2517227-A1 (CA)
Title: Transportable bicycle comprising a dismantlable-frame and reduced-size pedals and handlebars
Inventor: ELFANDI PATRICE
IPC: B62K15/00
Filed: 2004-01-08
Abstract: The bicycle has a framework, handle bar and lesser dimension pedals. An aperture of each section of tubes (9, 10) of the framework has an intermediate piece (101) with a radial bore parallel to each other to accommodate a cable switch. An axial bore (105) is prolonged by a wide portion (106) to accommodate a blocking system. A spring (111) propels a chassis to maintain bolts (108, 109) in the piece (101).
Patent CA-2518895-A1 (CA)
Inventor: METZGER TRACY ALAN
IPC: G06Q30/00
Filed: 2004-03-17
Abstract: L'invention concerne des systèmes et des procédés permettant d'effectuer des paiements par carte de crédit et de rapprocher l'inventaire et des transactions en liquide dans des véhicules mobiles, tels que, dans un mode de réalisation, à bord d'un aéronef de passagers. Le système met en oeuvre un dispositif portatif permettant d'effectuer des transactions de point de vente (POS) à distance. Dans un mode de réalisation, le dispositif portatif est un assistant numérique (PDA). Le système comprend un portail Internet en communication avec une base de données permettant d'entrer et de stocker des informations de transactions avant et après vente et d'inventaire pouvant être utilisées, notamment, aux fins de rapprochement.
Patent CA-2519299-A1 (CA)
Inventor: WYSOCKI THERESA
IPC: A61L15/28
Filed: 2005-09-14
Abstract: An absorbent article including a cover layer, a barrier layer and an absorbe nt system arranged between the cover layer and the barrier layer, the absorbent article being drapeable and possessing the absorbency attributes required of a sanitary napkin.
Patent CA-2519443-A1 (CA)
Inventor: FOX WILLIAM R JR
IPC: B28B19/00
Filed: 2004-03-17
Abstract: An apparatus and method for applying reference or grid markings to wallboard during the manufacturing process is disclosed. Reference or grid markings are applied to one sheet of cover paper (21A) at a location between the originating cover paper rolls and the cover paper creaser (50) or creasers (50). This is accomplished by locating and aligning multiple print heads (61) across the width of the continuously passing cover paper (21A), such that markings are ejected onto the cover paper (21A) in a specific and coordinated fashion. In addition to using any suitable commercially-available computer equipment to coordinate printer head (61) activity, this function is accomplished by attaching each print head (61) to a common horizontal support element (63) and provide individual adjustments that are perpendicular to, and with the directional flow of the passing cover paper (21A).
Patent CA-2520886-A1 (CA)
Inventor: CHEN SHIRLYNN
IPC: A61K9/48
Filed: 2004-03-23
Abstract: Disclosed are pharmaceutical compositions of hepatitis C viral protease inhibitors, and methods of using these compositions for inhibiting the replication of the hepatitis C virus (HCV) and for the treatment of an HCV  infection. These compositions are lipid based systems and comprise the hepatitis C viral protease inhibitor together with at least one pharmaceutically acceptable amine, at least one pharmaceutically acceptable base, at least one pharmaceutically acceptable oil and optionally one or more additional ingredients.
Patent CA-2524414-A1 (CA)
Title: Automated order mixing system
Inventor: LAFONTAINE DANIEL R
IPC: B65G1/137
Filed: 2005-10-26
Abstract: An automated order mixing system includes a mixing sub-system having a plurality of angled vertically stacked product guides feeding a mixing conveyor whereon a client's order of product cases is processed, the vertical stacking enabling the creation of a number of product feed paths within a relatively small floor space.
Patent CA-2525900-A1 (CA)
Inventor: STAGER BRADLEY R
IPC: B27C1/00
Filed: 2005-02-04
Abstract: A high speed planer head. Disclosed according to one aspect of the invention is a hub and a threaded member. The hub is axially disposed for rotation about an axis, and has a pocket for receiving a first knife against a supporting wall of the pocket. The threaded member has a frustoconical ramping portion for producing a wedging force against the knife when the threaded member is threaded into a threaded hole in the hub. According to another aspect of the invention, a second hub for carrying a second knife is provided, the second hub preferably being bolted to the first hub to that the hubs can be disassembled. The second knife preferably has two linear cutting edges and the second knife preferably has at least two curvilinear cutting edges and more preferably has four concave, semi-circular cutting edges that are spaced apart from one another with 90 degree rotational symmetry.
Patent CA-2526384-A1 (CA)
Title: Bone screw
Inventor: SCHLIENGER ANDRE
IPC: A61B17/86
Filed: 2004-02-23
Abstract: The invention relates to a bone screw (1) which comprises a shank (3) carrying a screw thread (2), and a front end (4) and a rear end (5). The external diameter "d" or the minor diameter "k" of the screw thread (2), in a center area (L4) of the shank (3), tapers from a larger dimension "d2" or "k2"  towards the front end (4) to a smaller dimension "d1" or "k1", whereby "d1"  and "k1" are unequal zero. The shank (3) is provided with a concentric, radially expandable sleeve (10). Said sleeve is positioned on the very part of the shank (3) which has the smaller external diameter "d1" or "k1".
Patent CA-2526851-A1 (CA)
Title: Method and apparatus for making preforms from glass fiber strand material
Inventor: KNUTSSON GORAN K
IPC: B29C43/02
Filed: 1997-11-27
Abstract: The present invention is directed to a method and apparatus for forming a preform from glass fiber strand material. The preform is formed by feeding continuous glass fiber strand material into a mold to form a continuous wool product in the mold; feeding a binder into the mold; compressing the mold to compact the wool product to a desired density; and heating the mold to cure the binder, such that a preform is formed having generally the shape of the compressed mold. The mold is then opened and the preform is removed from the mold.