baber/WOPTO huggingface dataset:
Patent NZ-335596-A (NZ)
Title: Diagnostic and therapeutic agents comprising microbubbles of a reporter, a surfactant and a vector
Inventor: KLAVENESS JO
IPC: A61K49/22
Filed: 1997-10-28
Abstract: Targetable diagnostic and/or therapeutically active agents, e.g. ultrasound contrast agents, having reporters comprising gas-filled microbubbles stabilised by monolayers of film-forming surfactants, the reporter being coupled or linked to at least one vector.
Patent NZ-336231-A (NZ)
Title: Bioremediation of trichloroethene (TCE) using butane utilising bacteria by providing butane as the primary food source
Inventor: PERRIELLO FELIX A
IPC: C02F3/00
Filed: 1997-11-05
Abstract: Butane-utilising bacteria are used to degrade hydrocarbon pollutants such as trichloroethene (TCE). In-situ or ex-situ techniques may be used to reduce or eliminate hydrocarbon pollutants from liquid, gas and solid sources. In a preferred embodiment, TCE concentrations in various aqueous environments are reduced by contacting a contaminated water source with butane-utilising bacteria in the presence of oxygen to degrade the TCE by co-metabolism or direct metabolism. Suitable butane-utilising bacteria include Pseudomonas, Variovorax, Nocardia, Chryseobacterium, Comamonas, Acidovorax, Rhodococcus, Aureobacterium, Micrococcus, Aeromonas, Stenotrophomonas, Sphingobacterium, Shewanella, Phyllobacterium, Clavibacter, Alcaligenes, Gordona, Corynebacterium and Cytophaga.
Patent NZ-500020-A (NZ)
Title: Process for preparing O-(3-amino-2-hydroxy-propyl)-hydroximic acid halides
Inventor: CSAKAI ZITA
IPC: A61K31/4453
Filed: 1997-12-05
Abstract: A process for preparing O-(3-amino-2-hydroxy-propyl)-hydroxymic acid halides of formula (I) wherein, R1 is phenyl, or pyridyl or thienyl or substituted phenyl, wherein the one or more substituent(s) may be halo and/or nitro; R2 and R3 are independently straight or branched lower alkyl; or R2 and R3 together with N form a 5 to 7-membered saturated heterocyclic group which may contain additional hetero atoms and may be substituted. The process involves reacting a carboxamide oxime of formula (II) wherein R1 is as specified above with reactive 3-amino-2-hydroxy-propane derivative diazotizing the O-substituted carboxamide oxime thus obtained with sodium nitrite in the presence of hydrogen halide and decomposing the diazonium salt.  If desired the optically active enantiomers may be separated and/or the resulting base may be reacted with an organic or mineral acid.  The carboxamide oxime of formula (II) is reacted with a 3-hydroxy azetidinium salt of formula (III) wherein R2 and R3 are a defined above and Y- is a salt forming anion, in a C1-4 alcoholic medium optionally containing water and made alkaline with an alkali hydroxide, and before diazotizing the O-substituted carboxamide oxime intermediate obtained, the reaction mixture is neutralised and the organic solvent is removed.
Patent NZ-500627-A (NZ)
Title: Hybrid propulsion system for road vehicles with three drive units coupled to power-splitting transmission
Inventor: BULLOCK KEITH JOSEPH
IPC: B60K6/12
Filed: 1998-04-17
Abstract: A hybrid propulsion system (100) is disclosed for use in road vehicle operations, which propulsion system includes a power splitting mechanical transmission, suitably a three shaft epicyclic gearbox (117, 118, 119), for coupling to a tailshaft (115) of the vehicle; a first drive unit (105) arranged for regenerative operation and coupled to the power splitting mechanical transmission (108); a second drive unit (110) arranged for regenerative operation and coupled, independently of said first drive unit, to the power splitting mechanical transmission (108); a third drive unit (113) for coupling, in parallel to said power splitting mechanical transmission, to the tailshaft; and propulsion control means (122) for coordinating operation of the drive units in accordance with a plurality of predetermined modes corresponding to a driving cycle of the vehicle. Two embodiments are disclosed, being suited to non-transit and transit operations, respectively. Methods for the optimal control of the hybrid propulsion system of each embodiment are also disclosed.
Patent NZ-507897-A (NZ)
Title: A wok or other cooking appliance with an electric heating element attached to the base
Inventor: EDMONDS NICHOLAS GRAHAM
IPC: A47J37/10
Filed: 2000-10-31
Abstract: A wok (1) includes a stainless steel cooking bowl (11) and a heating base (15) fixed to the bottom non-planar outside surface of the bowl.  The heating base includes a heating element (17) embedded on the cast body (16).
Patent NZ-507942-A (NZ)
Title: Viral chimeras comprised of CAEV and HIV-1 genetic elements
Inventor: DOUVAS ANGELINE
IPC: C12N15/09
Filed: 1999-04-30
Abstract: Disclosed is a polynucleotide, comprising portions of the genomes of caprine arthritis-encephalitis virus and HIV-1, resulting in a chimeric retrovirus referred to as a "CHIV." Also disclosed is a vaccine comprising a CHIV immunogen and a pharmaceutically acceptable carrier. A method of stimulating an immune response in vitro by contacting a lymphocyte with a therapeutically effective amount of a CHIV immunogen and a method of producing a CHIV viral preparation are also described.
Patent NZ-508375-A (NZ)
Title: Method for making composite board using phenol formaldehyde binder
Inventor: VERGARA ALEX
IPC: B27N3/08
Filed: 1999-06-23
Abstract: Wood composite boards are produced from a wood fibre treated with a slow curing, low alkalinity phenol formaldehyde (PF) resin. The resin treated wood fibre is consolidated and cured in a press using steam injection. The slow curing nature of the resin prevents pre-cure of the resin. The press using steam injection speeds curing so that boards can be produced in press cycles comparable to the curing of wood fibre treated with other resins in a press with no steam injection.
Patent NZ-508877-A (NZ)
Title: Composition for the prevention and/or treatment of osteoporosis and alterations due to menopause syndrome, comprising propionyl-L-carnitine and genistein
Inventor: CAVAZZA CLAUDIO
IPC: A61K31/205
Filed: 1999-06-17
Abstract: A composition that may take the form of a dietary supplement or of a medicament is disclosed which comprises as active ingredients propionyl L-carnitine or a pharmacologically acceptable salt thereof, and the isoflavone genistein (4',5,7-trihydroxyisoflavone) for the therapeutic treatment of osteoporosis and menopause syndrome.
Patent NZ-510103-A (NZ)
Title: Protein immunoreactive with anti-Ehrlichia canis and comprises a sequence of 688 amino acids, useful for inhibiting Ehrlichia canis infection
Inventor: WALKER DAVID H
IPC: A61K48/00
Filed: 1999-08-27
Abstract: Protein immunoreactive with anti-Ehrlichia canis and comprises a sequence of 688 amino acids, useful for inhibiting Ehrlichia canis infection. Disclosed is a 120-kDa protein gene of Ehrlichia canis, amplified by PCR using primers derived from the DNA sequences flanking the Ehrlichia chaffeensis 120-kDa protein gene. The recombinant E. canis 120-kDa protein contains 14 tandem repeat units with 36 amino acids each. The repeat units are hydrophilic and predicted to be surface-exposed. Also disclosed is that the recombinant E. canis 120-kDa protein is antigenic and reacts with sera from dogs convalescent from canine ehrlichiosis.
Patent NZ-511660-A (NZ)
Title: Weed and plant pests control apparatus and method
Inventor: SMITH ROBERT
IPC: A01M21/04
Filed: 1999-10-20
Abstract: A method of destroying or controlling unwanted vegetation and agricultural pests is disclosed. The method produces a jet stream of treatment fluid, being mixed combustion gas and superheated or dry steam for application to thermally destroy unwanted vegetation and posts. The method involves the use of a hydrocarbon burner and a water source.
Patent NZ-512708-A (NZ)
Title: Automated adjustable gluing apparatus for a packaging machine
Inventor: HENDRICKS TIMOTHY
IPC: B05C11/00
Filed: 2001-01-17
Abstract: An automated adjustable apparatus for dispensing glue includes a glue head assembly and an automated adjustment mechanism connected to the glue head assembly for adjusting the height of the glue head assembly to one of a plurality of predetermined heights corresponding to various heights of carton (19) configurations within a article grouping and packaging machine. The adjustment mechanism may include a first servomechanism such as pneumatic cylinders (70, 72) for moving the glue dispensing head into a plurality of predetermined height positions. The apparatus may include at least two glue dispensing heads (32, 34) on the service side of the machine into glue dispensing heads on the operations side of the machine and each independently controlled by actuation devices. Advantages include the elimination of manual adjustment on both the service and operations side of the machine to decrease changeover times. Additionally, the actuation device reduces the part number count over the prior art thus reducing component costs and maintenance costs
Patent NZ-514169-A (NZ)
Title: Automatically triggered slaughter bolt
Inventor: DOMIGAN IAN ROSS
IPC: A01M23/36
Filed: 2001-09-13
Abstract: The animal killing apparatus includes an impact rod (17) situated in the bore (3) of the device, a cartridge chamber (9), a firing pin (21) and an automatic triggering mechanism. The automatic triggering mechanism is arranged to trigger the firing pin whenever an animal is located within firing range of the device. Upon triggering the firing pin makes contact with a cartridge (8) in the cartridge chamber (9) causing detonation of the cartridge. Cartridge detonation in turn causes the impact rod  (17) to fire, impact the animal's head and thereby kill the animal. After firing the impact rod resets itself  via a resilient resetting means.
Patent NZ-515729-A (NZ)
Title: Flexible stretch-to-fit bags
Inventor: MEYER ERIC WALTER
IPC: B65D33/16
Filed: 2000-06-16
Abstract: The   present  invention  provides  a  flexible   bag comprising  at  least one sheet of flexible  sheet  material assembled  to  form  a  semi-enclosed  container  having  an opening  defined  by  a periphery. The  opening  defines  an opening  plane, and bag is expandable in response to  forces exerted  by  contents within the bag to provide an  increase in  volume  of  the bag such that said the accommodates  the contents placed therein.
Patent NZ-518638-A (NZ)
Title: Hyperimmunising a farm animal followed by administration of antigen to mammary gland to produce antibodies in farm animal milk
Inventor: LEE SANG HE
IPC: A61K39/395
Filed: 2000-10-31
Abstract: The present invention provides means and methods for obtaining an antibody in a mammary secretion product of a farm-animal comprising hyperimmunising said animal for the antigen via a mucosal passage of the farm animal, administering the antigen to a mammary gland and/or a supramammary lymph node of the farm animal and harvesting the milk of the farm animal. Particular antigens of interest include Toxins A and/or B of Clostridium difficile, and the antibody may be produced at a level of 200% of the average quantity present in the colostrum of the farm animal.
Patent NZ-519946-A (NZ)
Title: One-step coupling process for forming peptide linkages
Inventor: ALVHALL JORGEN
IPC: C07D205/04
Filed: 2001-01-30
Abstract: A process for the production of a compound of formula (I) is disclosed, which process comprises reaction of a compound of formula (II), with a compound of formula (III), wherein n R1, R2 and R3 are as defined in the specification. This process is a one-step process wherein peptide linkage is formed in which N-carboxyanhydrides (NCAs) are coupled to inter alia cyclic amino acid amide derivatives thereby producing the compound of formula (I).
Patent NZ-521182-A (NZ)
Title: Human antibodies against eotaxin comprising VH adn VL domains and their use
Inventor: VAUGHAN TRISTAN JOHN
IPC: A61P17/02
Filed: 2001-03-02
Abstract: A specific binding member that binds human eotaxin comprises an antibody VH domain comprising a VH CDR1, a VH CDR2 and VH CDR3 and further comprises an antibody comprising a VL CDR1, a VL CDR2 and VL CDR3, wherein the VH CDR1, the VH CDR2 and the VH CDR3 consist of the amino acid sequences of SEQ ID NO: 5, SEQ I D NO: 6, and SEQ ID NO:7 respectively. Also described is a specific binding member that binds eotaxin and comprises an eotaxin antigen-binding site formed by the CAT-212 VH domain (SEQ ID NO:2) and the CAT-212 VL domain (SEQ ID NO4). Methods for producing specific binding members or antibody VH or VL domains, host cells, nucleic acids and methods of obtaining specific binding members that bind eotaxin are described.
Patent NZ-521202-A (NZ)
Title: Method for the preparation of citalopram by reduction and its intermediates
Inventor: PETERSEN HANS
IPC: A61K31/343
Filed: 2001-03-07
Abstract: A method for the preparation of citalopram comprises reduction of a compound of formula (III) wherein X is a cyano group, or a group which can be converted to a cyano group, and where X is not a cyano group followed by the conversion of X to a cyano group, and isolation of citalopram in the form of the base or as a pharmaceutically acceptable acid addition salt thereof. Also described is the compound of formula (V) wherein X is a cyano group or a group which can be converted to a cyano group or an acid addition salt thereof and an antidepressant pharmaceutical composition comprising citalopram manufactured by the method described above.
Patent NZ-523564-A (NZ)
Title: Fumigation apparatus with absorption bed
Inventor: BRASH KENNETH GEORGE
IPC: A01M17/00
Filed: 2001-07-12
Abstract: A fumigation module that is attachable to the opening (e.g. door or window) of a chamber adapted to contain produce in need of fumigation. The module (8) has a fumigant inlet hole (12) to allow fumigant into the fumigation chamber, an extraction pipe (28) connected to another hole (30) with a fan (34) to remove a majority of the fumigant from the chamber and an absorption bed (40) designed to absorb some of the fumigant extracted from the chamber. In this way, the fumigant can be introduced and then removed from the chamber without the toxic fumigant chemicals being released into the air.
Patent NZ-526240-A (NZ)
Title: Non-water and non-solvent based material comprising a drying oil, an extender and a preservative and method for treatment of timber
Inventor: COBHAM PETER RAYNOR SOUNDY
IPC: A01N53/08
Filed: 2001-12-17
Abstract: A non-water and non-solvent based material for treating wood comprises a preservative and a carrier, the carrier being selected such that it remains mobile within the wood and provides for migration of the preservative within the treated wood. The carrier includes a drying oil selected from linseed oil, fish oil or another drying oil and an extender such as heating oil. The preservative includes an insecticide, termicide, fungicide, mouldicide or the like or mixtures thereof. The material may further comprises drying agent to accelerate drying of the drying oil. Also described is a method for treating wood by contacting the wood with the material.
Patent NZ-527790-A (NZ)
Title: Method and apparatus for disinfecting a product by surface treatment using a combination of steam and ultrasound
Inventor: KREBS NIELS
IPC: A61L2/07
Filed: 2002-03-27
Abstract: An apparatus and method for combating germs on the surface of products, in particular of food products, employing a combination of steam and ultrasound. Pressurized water is passed from steam chamber 10, through steam passage 3, to an opening 2, conveying the steam to a cavity 4, in which the steam is made to oscillate at a frequency which is preferably ultrasonic. The diffused oscillating steam 7 is directed towards solid products 8 which are moving along conveyor 9. The oscillations in the steam prevent the steam from heating the products excessively, while germs presents on the surface of the products are heated and killed.
Patent NZ-529476-A (NZ)
Title: Methods of manipulating and sequencing nucleic acid molecules using transposition and recombination
Inventor: BRASCH MICHAEL A
IPC: C12N15/10
Filed: 2000-10-25
Abstract: Generally described are methods, kits and compositions for use in manipulating nucleic acid molecules, particularly cloning, sequencing, amplifying and mutating such molecules. In particular, the use of recombination sites and recombinational cloning are described to manipulate, select and analyse nucleic acid molecules of interest.
Patent NZ-531913-A (NZ)
Title: Apparatus for filling container to threshold weight using dump hopper and make up filling apparatus
Inventor: HERMANS HENRICUS
Filed: 2004-03-23
Abstract: Container 10 is filled by dumping material accumulating in hopper 1, and by final fill material via auger 7. Container 10 is supported (typically via load cell 9) so as to be weighed during filling.
Patent NZ-534737-A (NZ)
Title: 2-amino-4-bicyclyl amino-6h-1.3.5-triazines, method for the production and use thereof as herbicides and plant growth regulators
Inventor: MINN KLEMENS
IPC: C07D495/04
Filed: 2003-02-06
Abstract: 2-Amino-4-bicyclylamiono-6 H-1, 3, 5-triazines, process for their preparation anduse as herbicides and plant growth regulators. Compounds of formula (I) and salts thereof are disclosed.
Patent NZ-537301-A (NZ)
Title: Therapeutic molecules and methods-1
Inventor: MORAND ERIC FRANCIS
IPC: C07C333/04
Filed: 2003-06-06
Abstract: Disclosed is the use of a compound of formula (I), for the treatment of diseases for which MIF cytokine or MIF biological activity is implicated, such as autoimmune diseases, solid or haemopoitic tumours and chronic or acute inflammatory diseases, wherein: X is selected from -O-, -S-, -C(R5)(R5')- or -N(R6)-, Y is selected from -N(R7)-, -O-, -S- or -C(R7)2-, Z is selected from -C(O)-, -C(S)-, -C(=NR6)-, -S(O)- or -S(O)2-, and the remaining substituents are defined herein.
Patent NZ-537687-A (NZ)
Title: Buffered formulations for concentrating antibodies and methods of use thereof
Inventor: YANG TZUNG-HORNG
IPC: A61K47/12
Filed: 2003-06-23
Abstract: A concentrated antibody composition comprising an antibody solution and histidine or acetate buffer at a concentration range of from about 2 to 28 mM, which composition does not contain an additional aggregate-reducing or viscosity-reducing additive.
Patent NZ-538464-A (NZ)
Title: Porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase
Inventor: PHELPS CAROL J
IPC: C12N5/06
Filed: 2003-08-21
Abstract: Described is a porcine animal, tissue, organ, cells and cell lines, which lacks any expression of functional alpha 1,3 galactosyltransferase (alpha 1,3GT). These animals, tissues, organs and cells can be used in xenotransplantation and for other medical purposes.
Patent NZ-539310-A (NZ)
Title: Regulation of aggrecan gene expression using specific and selective electrical and electromagnetic signals
Inventor: BRIGHTON CARL T
IPC: A61N1/32
Filed: 2003-09-24
Abstract: A device for the treatment of at least one of osteoarthritis, rheumatoid arthritis, cartilage injury, or cartilage defect is disclosed. The device includes a signal source that generates at least one specific and selective signal, electrodes, and one or more coils or other field generating devices. These devices are connected to the signal source so they receive the specific and selective signal, where they are operatively disposed with respect to the target cartilage tissue. The electrodes and coils or other field generating devices, upon receipt of the specific and selective signal causes the generation of an electric field that is specific and selective for up-regulating gene expression of aggrecan mRNA in the target cartilage tissue. The signal source controlling and varying the duration of the time of application of the specific and selective signal, where the signal has a duty cycle, is applied to the electrodes, one or more coils, or other field generating devices, so as to selectively up-regulate gene expression of aggrecan mRNA in the target cartilage tissue.
Patent NZ-539414-A (NZ)
Title: Machine designed as a centrifugal compressor applied as organic rankine cycle turbine
Inventor: BRASZ JOOST J
IPC: F04D29/44
Filed: 2003-11-12
Abstract: A machine designed as a centrifugal compressor is applied as an organic rankine cycle turbine by operating the machine in reverse. In order to accommodate the higher pressures when operating as a turbine, a suitable refrigerant is chosen such that the pressures and temperatures are maintained within established limits. Such an adaptation of existing, relatively inexpensive equipment to an application that may be otherwise uneconomical, allows for the convenient and economical use of energy that would be otherwise lost by waste heat to the atmosphere.
Patent NZ-540049-A (NZ)
Title: New expression system from Rhodococcus
Inventor: VAN DER GEIZE ROBERT
IPC: C12N15/74
Filed: 2003-12-02
Abstract: An isolated polynucleotide comprising the kstD promoter from Rhodococcus erythropolis. The polynucleotide can very advantageously be used as a controllable transcription activator. Said controlling function can be provided by providing said isolated polynucleotide with a nucleotide sequence encoding a transcription regulator of said promoter. In the present invention, such a transcription regulator may be externally induced, such as by introduction of steroidal compounds. In an alternative embodiment of the present invention the isolated polynucleotide may comprise the kstR gene or a homologue or a functional part thereof as the transcription regulator of the kstD promoter.
Patent NZ-541232-A (NZ)
Title: Pyrrolopyridazine derivatives
Inventor: ABE YOSHITO
IPC: C07D487/04
Filed: 2003-12-26
Abstract: Disclosed are pyrrolopyridazine derivatives of formula (I), their use as a medicament, the process for their preparation and use for the treatment of PDE-IV or TNF-alpha mediated diseases.
Patent NZ-541578-A (NZ)
Title: Use of polydextrose in edible products to synergistically enhance sweetness with other sweeteners
Inventor: LAURIDSEN KIRSTEN
IPC: A23L27/30
Filed: 2004-02-25
Abstract: The disclosure relates to the use of polydextrose for the sweetening of edible products. The disclosure relates especially to the use of polydextrose for synergistically enhancing the sweetness of sweet tasting sugar compounds selected from sucrose, fructose, glucose, lactose, maltose, maltulose, isomaltulose, galactose and mixtures or syrups thereof.
Patent NZ-544911-A (NZ)
Title: RG1 antibodies and uses thereof
Inventor: HARKINS RICHARD
IPC: C12Q1/68
Filed: 2004-07-20
Abstract: Disclosed are antibodies, and antigen-binding antibody fragments, directed against an RGI polypeptide. It further relates to methods for utilizing the antibodies, and antibody fragments, for diagnostic and therapeutic applications, in particular for cancer.
Patent NZ-546162-A (NZ)
Title: Therapeutic treatment
Inventor: MEHTA JAY LAL
IPC: A61K31/4184
Filed: 2004-09-22
Abstract: Disclosed is a combination comprising candesartan or a pharmaceutically acceptable salt thereof and rosuvastatin or a pharmaceutically acceptable salt thereof for use in the prevention or treatment of atherosclerosis.
Patent NZ-548124-A (NZ)
Title: Packaging unit for absorbent articles
Inventor: HANSSON ROY
IPC: B65D85/07
Filed: 2004-12-16
Abstract: A packaging unit (42) for absorbent articles (1) is disclosed. The packaging unit comprises a number of folded articles, the folded parts (11) of the articles being arranged towards one of the sides of the packaging unit. The fold areas of a number of absorbent articles are arranged at a distance from the side of the packaging and the fold areas of a number of the absorbent articles are arranged in direct contact (17) with the side of the packaging unit. The folded areas at a distance from the side of the packaging unit are offset by a distance of 5-50 mm in relation to the articles arranged with their folded areas in direct contact with the with the side of the packaging unit.