baber/WOPTO huggingface dataset:
Patent DK-2292788-T3 (DK)
Inventor: VAN EIJK MICHAEL JOSEPHUS THERESIA
IPC: G16B20/20
Filed: 2006-06-23
Granted: 2012-07-23
Abstract: The invention identifies PD-1 as a receptor for B7-4. B7-4 can inhibit immune cell activation upon binding to an inhibitory receptor on an immune cell. Accordingly, the invention provides agents for modulating PD-1, B7-4, and the interaction between B7-4 and PD-1 in order to modulate a costimulatory or an inhibitory signal in an immune cell resulting in modulation of the immune response. The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
Patent DK-2420593-T3 (DK)
Inventor: GONG QING
IPC: C23C18/20
Filed: 2011-07-14
Granted: 2013-07-08
Abstract: Metalized plastic substrates and a manufacturing method thereof are provided herein. The method includes providing a plastic substrate made of a plastic material, in which a plurality of accelerator particles is dispersed. The accelerator particles are made of a compound selected from the group consisting of: CuFe 2 O 4-6 , Ca 0 . 25 Cu 0.75 TiO 3-² , and TiO 2-Ã , and ´, ², Ã is deemed to be 0.05‰¤´‰¤0.8, 0.05‰¤²‰¤0.5, and 0.05‰¤Ã‰¤1.0. The method includes the step of removing plastic material in a determined area of a surface of the plastic substrate. The method further includes plating the exposed surface of the plastic substrate to form a first metal layer, and then plating the first metal layer to form a second metal layer.
Patent DK-3126617-T3 (DK)
Inventor: CARRAGHER PAUL
IPC: E21B31/00
Filed: 2015-08-14
Granted: 2018-08-20
Abstract: A first aspect of the invention provides a gas or oil well tubing having an annular packer mounted thereon, wherein the annular packer is formed from an eutectic alloy. By prefabricating the annular packer on the tubing it can be placed in situ from the outset and thus can be active by melting at any time to form a eutectic seal quickly and easily. An annular packer with by-pass conduits is also provided to enable cement to be pumped past the annular packer when it is in situ. The annular packer is further provided with conduit clearance means to clear cement from within the conduits.
Patent DK-0391311-T3 (DK)
Inventor: AMMERMANN EBERHARD DR
IPC: C07D405/14
Filed: 1990-04-02
Granted: 1994-04-05
Abstract: 1-Alkoxy-1-azolylmethyloxiranes of the general formula I <IMAGE>  in which R<1> and R<2> are identical or different and in each case represent C1-C8-alkyl, C3-C8-cycloalkyl, C5-C8-cycloalkenyl, tetrahydropyranyl, norbornyl, pyridyl, naphthyl, biphenyl or phenyl, it being possible for each of these radicals to be monosubstituted to trisubstituted by halogen, nitro, phenoxy, amino, alkyl, alkoxy or haloalkyl, each of which has 1 to 4 carbon atoms,  R<3> represents C1-C4-alkyl,  X represents the radical CH or N, and their acid addition salts and metal complexes which are tolerated by plants, fungicides containing these compounds, their preparation, and their use for controlling fungi.
Patent DK-0426098-T3 (DK)
Inventor: GRETZ NORBERT DR
IPC: A61K33/08
Filed: 1990-10-30
Granted: 1994-10-31
Abstract: Phosphate binders for oral prescriptions with alpha-keto-glutaric acid calcium salt as the active substance and, where appropriate, further organic or inorganic phosphate binders and additives.
Patent DK-0444302-T3 (DK)
Inventor: NYCZ COLLEEN M
IPC: G01N33/569
Filed: 1990-12-21
Granted: 1996-09-02
Abstract: A method for immunoassay for a ligand is performed on a porous membrane with alkaline phosphatase as the label. The assay protocol includes a wash step with an organic acid to deactivate endogenous alkaline phosphatase. The invention includes a kit of materials for performing the assay.
Patent DK-0384588-T3 (DK)
Inventor: THOMPSON BJORN J
IPC: B65D33/34
Filed: 1990-01-30
Granted: 1994-02-28
Abstract: A reclosable, hermetically-sealed flexible package which has an inner, hermetic peel seal (16) and a reclosure seal comprised of interlocking closure strips (17, 18) is provided with a tamper-evident feature (21) located peripheral to the reclosure seal. The tamper-evident feature (21) must be visibly disrupted to gain access to the reclosure seal.
Patent DK-0478680-T3 (DK)
Inventor: IDSUND AKE
IPC: A61B17/50
Filed: 1990-06-21
Granted: 1995-04-10
Abstract: A tweezer for removal of ticks has two legs (10, 12), connected at one end (11) by a loop formed spring, pinched together partly within a movable cylinder (26), which through the action of a coil spring (24) is pushed against the bent portions of the legs' (10, 12) end parts in order to exert a preset squeezing force between the end parts and their sharp edged gripping points (19). By retracting the cylinder (26) the gripping points (19) are opened and when the cylinder (26) is released, the legs' (10, 12) end portions and their gripping points (19) can grasp the tick (40) and its head (38) with such a predetermined force that the tweezer will lose its grip if the tick's head (38) has not first been loosened by turning. The turning is brought about by turning the cylinder (26), which maintains the predetermined pinching force by the help of the coil spring (24).
Patent DK-0532562-T3 (DK)
Inventor: OTTOW ECKHARD
IPC: C07J1/00
Filed: 1991-06-03
Granted: 1995-05-15
Abstract: PCT No. PCT/EP91/01018 Sec. 371 Date Nov. 30, 1992 Sec. 102(e) Date Nov. 30, 1992 PCT Filed Jun. 3, 1991 PCT Pub. No. WO91/18918 PCT Pub. Date Dec. 12, 1991.A process for the production of 10 beta -H-11 beta -(substituted phenyl) steroids of the formulae Ia or Ib set forth in the claims by reduction of a compound of the formula III:    <IMAGE>  (III)  followed by cleaving with a strong acid or partial cleaving with a less strong acid. Reduction with an electropositive metal in an electron-solvating solvent is preferred.
Patent DK-0486666-T3 (DK)
Inventor: ROBERTSON ALAN DUNCAN
IPC: C07D403/06
Filed: 1991-06-06
Granted: 1998-03-30
Abstract: Heterocyclic cpds of formula (I), and their salts are new n = integer from 0 to 3. W = gp of formula (i), (ii) or (iii). R = H or 1-4C alkyl, X = -0-, -S-, -NH- or -CH2-Y = 0 or S. The chiral centre inm (i) or (ii) is in its (S) or (R) form or is a mixt thereof in any proportion. Z = a gp of formula (iv), (v) or (vi), R1 and R2 are independently H or 1-4C alkyl. R3 = H or 1-4C alkyl. Also claimed are the use of (I) in pharmaceutical compsns and processes for their prepn. Pref n = 1, W = a gp of formula (i) wherein R = H, X = -0- and Y = 0 Z = a gp of formula (iv) or (vi) R1 = R2 = H or CH3.
Patent DK-0509080-T3 (DK)
Inventor: KAKKAR VIJAY VIR
IPC: A61K38/08
Filed: 1991-11-06
Granted: 2000-09-18
Abstract: Peptides useful as inhibitors or substrates of thrombin are of the formula whereinX is H, CH<sub>3</sub> or an N-protecting group;Y is [CH<sub>2</sub>]<sub>n</sub>-Q or where Q is H, amino, amidino, imidazole, guanidino or isothioureido and n is 1-5, preferably 3-5, or Y is nitrophenyl, cyanophenyl, aminophenyl, pyridyl or the side chain of His, or is C<sub>3</sub>-C<sub>9</sub> alkyl or C<sub>5</sub>-C<sub>10</sub> aryl or alkylaryl optionally substituted by up to three groups selected from hydroxy and C<sub>1</sub>-C<sub>4</sub> alkoxy,Z typically a boronate or phosphonate group, for example a boron joined to the residue of a diol,Aa<sub>1</sub> is D-Phe or selected from certain unnatural hydrophobic amino acids, andAa<sub>2</sub> is Pro or certain Pro analogues.
Patent DK-0598141-T3 (DK)
Inventor: LEBBAR THAMI
IPC: A23P10/25
Filed: 1992-11-17
Granted: 1997-07-21
Abstract: The present invention relates to a process for obtaining agar-agar that can be dissolved quickly in water at a temperature higher than its gelling temperature. It consists of using the classical agar-agar in the form of dried powder or dehydrated agar gel granules obtained after the operation of mechanical pressing or of freeze-thawing, and of passing it through a single-screw or twin-screw extruder. The process can be carried out in mixture with principally water and other products such as the locust bean gum, the guar gum, sugar, peptones or dispersants like the metarine, fatty acids or organic silicones. Such process allows to produce, at a reduced price, an agar-agar with properties of instantaneous dissolution in hot water at a temperature higher than its gelling temperature.
Patent DK-0563490-T3 (DK)
Inventor: BERNARD ALAIN
IPC: E04C5/16
Filed: 1992-06-09
Granted: 1997-06-02
Abstract: The invention relates to a method for making a mechanical concrete bar joint and to such a mechanical joint, and to a concrete bar permitting the implementation of the method, and to an installation for preparing concrete bars. It will be used in the concrete construction sector. The method involves joining at least one concrete bar (1) to another concrete bar (2), or to an anchoring point, by way of a tapped joining sleeve (3), the said concrete bar having a nominal cross-section  PHI , and at least one reinforced end (4), turned back and threaded, such that the thread root diameter d2 is equal to or greater than the nominal cross-section  PHI  of the bar. According to the invention, the reinforced end (4) is obtained by a double upsetting, a first axial one permitting an increase in the diameter of the concrete bar, and a second radial one during the threading by means of a rolling technique. <IMAGE>
Patent DK-0536071-T3 (DK)
Inventor: ARON JEROME
IPC: B60B33/02
Filed: 1992-10-02
Granted: 1996-09-02
Abstract: The present invention relates to a haymaking machine, especially a tedder-crop, comprising a framework carrying several rotors. Each rotor has a carrying spindle to which a small roller is connected. The said framework has a beam on which a coupling device is articulated. It is noteworthy in that it comprises a control member (21) for transposing the framework (1) together with the rotors (2) about the articulation (5) from a first working position into at least a second working position and that under the rotors (2) there are located means (55) which block the small rollers (19) with respect to their respective carrying spindles (16) in the first working position and which automatically release them when the machine is transposed into the second working position. <IMAGE>
Patent DK-0589998-T3 (DK)
Inventor: HOFMANN GEORG
IPC: B22D41/50
Filed: 1992-06-22
Granted: 2000-06-05
Abstract: The invention is directed to an immersion casting pipe for feeding molten steel from a casting vessel into a mold having wide side walls and narrow side walls for the production of flat products. The immersion casting pipe has a pipe piece which adjoins the casting vessel and expands in cross section in the direction of the narrow side walls of the mold. The pipe piece is provided with a central base member at the lower end which allows for outlet openings for the melt. For the purpose of developing an immersion outlet which allows higher slab withdrawal speed of up to 6 m/min with slabs measuring 50 to 100 mm in thickness and 600 mm to 2000 mm in width, the inner wall of the portion of the immersion casting pipe which widens in cross section forms flow channels in conjunction with the opposite wall parts of the base member. The axes of the flow channels enclose an angle  alpha  between 10 DEG  and 22 DEG , where the smaller angle corresponds to a distance of approximately 600 mm between the narrow side walls of the mold and the larger angle corresponds to a distance of 2000 mm or more between the narrow side walls of the mold. The distance between the wide side walls of the mold is 50 to 100 mm.
Patent DK-0602050-T3 (DK)
Inventor: CLARK ROSS G
IPC: A61K38/27
Filed: 1992-06-16
Granted: 1997-06-02
Abstract: A method is disclosed for stimulating a mammal's or avian's immune response, particularly immune-compromised mammals, by administration of IGF-I, alone or in combination with growth hormone. Preferably, the IGF-I is native-sequence, mature human IGF-I.
Patent DK-0595142-T3 (DK)
Inventor: LEI XIAO PING
IPC: D03D15/527
Filed: 1993-10-16
Granted: 1996-07-15
Abstract: In a method for the flame-retardant treatment of fabrics by impregnation with a condensate of a tetrakis (hydroxyorgano) phosphonium salt and, e.g., urea, the addition of one or more protonated and neutralized amines to the impregnation solution increases the efficiency of fixation of the phosphonium salt within the fibres, improves its uniform distribution within the system and leads to improved flame-retardant and water-resistant properties.
Patent DK-0556096-T3 (DK)
Inventor: BURNOUF MIRYANA NEE RADOSEVICH
IPC: A01N1/02
Filed: 1993-02-04
Granted: 1999-06-14
Abstract: The invention relates to a composition intended to stabilise blood plasma during pasteurisation, the blood plasma being whole or devoid of cryoproteins. The composition according to the invention makes it possible to pasteurise very large quantities of plasma (of the order of 60 litres). The invention also relates to the method for pasteurisation of the plasma using the stabilising composition. The pasteurised plasma obtained is intended for therapeutic use.
Patent DK-0613693-T3 (DK)
Inventor: HARDY CRAIG J
IPC: A61P17/00
Filed: 1994-03-02
Granted: 1999-08-23
Abstract: The invention provides water swellable wound dressing materials comprising from 5% to 50% of an alginate ester of a C1-C6 polyhydric alcohol; from 50% to 95% of a humectant consisting of one or more C1-C6 monohydric or polyhydric alcohols; and from 0% to 30% of water, the percentages being calculated by weight based on the weight of the material when anhydrous. The preferred alginate ester is propylene glycol alginate (PGA). The materials swell but do not dissolve in cold or warm water. Insolubility is achieved by the addition of polyvalent cations such as calcium ions, or by covalent cross-linking of the PGA, or by adding from 10 to 35% by weight of a water-swellable polysaccharide such as gelatin, or by adding from 5% to 20% by weight of a cationic polymer such as chitosan.
Patent DK-0675678-T3 (DK)
Inventor: FERGUSON MARK WILLIAM JAMES
IPC: A01K41/00
Filed: 1993-12-16
Granted: 1999-05-03
Abstract: PCT No. PCT/GB93/02565 Sec. 371 Date Aug. 23, 1995 Sec. 102(e) Date Aug. 23, 1995 PCT Filed Dec. 16, 1993 PCT Pub. No. WO94/13132 PCT Pub. Date Jun. 23, 1994A method of hatching eggs of avian species, especially chickens, which comprises carrying out at least one cycle of steps (a) and (c) as follows: (a) incubating the eggs in a first, baseline ambient environment which is normal for hatchery incubation of the eggs of the avian species in the prevailing climatic conditions and then during a sex-sensitive time window of embryonic development, (b) altering the ambient environment to shifted conditions for a period of time effective to bias the normal phenotypic sex ratio of the embryos, without significant adverse effect on the average mortality rate, and (c) thereafter restoring the incubation conditions to or towards normal and allowing the eggs to hatch. Preferably the ambient environment comprises a temperature of 37.5 DEG -38 DEG  C. and the shifted conditions comprise reduced temperature, especially a temperature maintained at about 22 DEG  C. for a period of from 18 to 42 hours. The method may be used to produce birds which are chromosomally male (ZZ) but phenotypically female or chromosomally female (ZW) but phenotypically male.
Patent DK-0691058-T3 (DK)
Inventor: ORTIZ LUIS R
IPC: H04M1/24
Filed: 1994-03-02
Granted: 1998-09-07
Abstract: A self-diagnostic system for checking all functions of a cellular-transceiver system having a cellular-interface unit (10), which interface unit (10) couples a standard telephone set (T,R) to a cellular transceiver, which interface unit (10) converts the DTMF or pulse-type dialing signals into digital format for transmission to the cellular transceiver in which, the dialed number made on the landline telephone may be used to call a number over the cellular system. The present invention not only monitors and checks the proper functioning of the transceiver and associated power supply (figure 11), but will also monitor and check the interface unit (10).
Patent DK-0710414-T3 (DK)
Inventor: HOHENACKER THOMAS
IPC: H04H60/31
Filed: 1994-04-14
Granted: 1997-12-22
Abstract: PCT No. PCT/EP94/01161 PCT Filed Apr. 14, 1994 PCT Pub. No. WO94/24785 PCT Pub. Date Oct. 27, 1994A device for storing picture information displayed on a television screen consists of a storage medium made of a photosensitive material which may be secured to the surface of the screen by an active adhesive layer on the screen.
Patent DK-0695265-T3 (DK)
Inventor: NEIDHART FRITZ
IPC: B65D19/40
Filed: 1994-04-29
Granted: 1998-02-23
Abstract: PCT No. PCT/GB94/00937 Sec. 371 Date Jan. 3, 1996 Sec. 102(e) Date Jan. 3, 1996 PCT Filed Apr. 29, 1994 PCT Pub. No. WO94/25355 PCT Pub. Date Nov. 10, 1994The present invention relates to transport containers with side walls connected to one another at their edges by clamps and with as a base a pallet which is also fastened to the side walls by clamps. The pallet is a four-sided pallet, with blocks arranged at the corners and possibly at predetermined distances along the edges of the base plate of the pallet and in the middle thereof. The outwardly directed side surfaces of the blocks are flush with the outer surfaces of the adjoining side walls. The transport container has skid planks which are fastened to the underside of the blocks. The outwardly directed side surfaces of the skid planks at least over part of their height, maintain a constant distance from the outwardly directed side surfaces of the block, and the distance is determined by the thickness of the side walls plus a handling play which is not greater than about half a wall thickness.
Patent DK-0679491-T3 (DK)
Inventor: KLOTZ BERND
IPC: B29C45/17
Filed: 1995-02-27
Granted: 2000-07-24
Abstract: The injection moulding machine, for the prodn. of hollow articles, has a core composed of an inner (11) and outer (12) sleeve, to be moved in a sliding action into a position to fill a wall hollow zone (19) and into a position to close the hollow zone. The inner sleeve (11) can slide axially in relation to the outer sleeve (12). The sleeve (11, 12) enclose a ring vol. (16) at the edge of the wall hollow zone (19) for connection through the relative sleeve sliding movement. A feed channel (15) between the sleeves (11, 12) can be connected to a compressed gas feed jet (14). A piston/cylinder unit (13) at the end of the core sleeves (11, 12) away from the wall hollow zone (19) is subjected to the pressure gas feed from the jet (14) to give an axial sliding movement of the base piston (17) formed as the container base in the inner sleeve (11). <IMAGE>
Patent DK-0746659-T3 (DK)
Inventor: PRESTON JOHN CLEMENT
IPC: E04F17/10
Filed: 1995-02-24
Granted: 2000-05-29
Abstract: PCT No. PCT/AU95/00094 Sec. 371 Date Sep. 12, 1996 Sec. 102(e) Date Sep. 12, 1996 PCT Filed Feb. 24, 1995 PCT Pub. No. WO95/23264 PCT Pub. Date Aug. 31, 1995A drop delivery debris disposal chute formed of a continuous trough sectioned body having an open face, and a plurality of cover elements each secured to span the open face to constitute a respective part of a closure wall of the chute, wherein each of a plurality of duct access openings in the closure wall is constituted by a gap between neighboring spaced apart cover elements, and at least two inlet structures supporting the duct fixedly mounted to a building floor and including an intake opening and an inclined race extending from the intake opening to a corresponding duct access opening, and wherein the spacing between neighboring duct access openings is established to bring each access opening into register with the race of a corresponding inlet structure by use of a cover sheet in overlapping relationship with a cover element.
Patent DK-0755403-T3 (DK)
Inventor: SUEHARA AKIHIRO
IPC: A61P31/04
Filed: 1995-04-26
Granted: 2000-02-14
Abstract: To provide a method of efficiently separate protective components of Bordetella pertussis. On the basis of differences in adsorbability to calcium phosphate gel formed by adding calcium ions to a Bordetella pertussis culture in the presence of excess phosphate ions, protective components of Bordetella pertussis are separated from the Bordetella pertussis culture. Traditionally, protective components of Bordetella pertussis have been separated using different purification methods for the respective components. According to the present invention, the use of the same means of purification for all subject components makes it possible to purify each component with high efficiency and high recovery rate, an aspect very advantageous for industrial production. It is also possible to efficiently produce an improved purified pertussis component vaccine comprising an effective combination of pertussis filamentous hemagglutinin (FHA), pertactin (PRN, 69K-OMP), pertussis fimbriae (FIM) and pertussis toxin (PT).
Patent DK-0817654-T3 (DK)
Inventor: GRABENKORT RICHARD W
IPC: A61M5/28
Filed: 1996-03-21
Granted: 2003-01-06
Abstract: A drug delivery system includes first drug (110) and second diluent (182) syringe assemblies which are respectively pre-filled with a drug concentrate and a liquid diluent. The diluent syringe assembly is positionable in operative association within a sterility maintenance sleeve (150) of the first syringe assembly so that the assemblies are joined in fluid communication. This fluid transfer connection permits the diluent to be transferred from the second syringe assembly into a sterile mixing chamber defined by a reciprocable stopper (134) in the first syringe assembly. Thereafter, the second syringe assembly can be moved with respect to the barrel of the first syringe assembly so that the resulting mixture can be delivered for patient administration.
Patent DK-0862659-T3 (DK)
Inventor: WILLEM DUYVESTEYN P C
IPC: C22B23/00
Filed: 1996-05-08
Granted: 2000-12-18
Abstract: A method is provided for recovering nickel from high magnesium-containing lateritic ores which also contain iron. The ores which are referred to as saprolitic ores are subjected to leaching with a mineral acid from the group consisting of HCl, H2SO4 and HNO3, HCl being preferred. Following leaching with HCl, for example, the pregnant solution obtained is separated from undissolved solids and the nickel preferably recovered by contacting the solution with a resin selective to nickel absorption. The raffinate remaining which contains iron and magnesium chlorides may be subjected to pyro-hydrolysis to produce their respective oxides and free HCl for recycle into the leaching system. The nickel is extracted from the resin using a stripping solution of said acid, and the nickel thereafter extracted from the nickel-loaded stripping solution.
Patent DK-0880156-T3 (DK)
Inventor: LINEK REINER
IPC: H01H50/54
Filed: 1997-10-11
Granted: 2002-07-15
Abstract: The switching device has parallel main (3) and auxiliary (4) contact pieces. At least one connector (7,6) each for the auxiliary and main contact pieces are arranged on the same side of the switching device. At least one Ohmic resistance (8) is connected between the main and auxiliary contact pieces of each phase. The auxiliary contact pieces are made before the main ones and broken after the main ones. Each resistance is arranged directly underneath the connector for the auxiliary contact piece in a hollow chamber (14) in a housing (13) of insulating material extending in the direction of the main contact piece's connector.