baber/WOPTO huggingface dataset:
Patent AU-2013206218-B2 (AU)
Title: Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
Inventor: XU LINA
IPC: C07D209/82
Filed: 2013-06-07
Granted: 2016-06-30
Abstract: POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF ARYL- AND HETEROARYLPROPIONIC ACIDS WITH VERY FAST SKIN PENETRATION RATE Abstract Striuture 1 Sntradar 2 The novel positively charged pro-drugs of aryl- and heteroarylpropionic acids in the general formula (1) 'Structure 1' and general formula (2) 'Structure 2' were designed and synthesized. The compounds of the general formula (1) 'Structure 1' and general formula (2) 'Structure 2' indicated above can be prepared from functional derivatives of naproxen, suprofen, a-methyl-(p-chlorobenzoyl)-5-methoxy-2 methylindole 3-acetic acid, flurbiprofen, carprofen, pranoprofen, benoxaprofen, alminoprofen, tiaprofenic acid, pirprofen, zaltoprofen, bermoprofen, loxoprofen, indoprofen, fenclorac, oxaprozin, fenbufen, orpanoxin, ketorolac, clidanac, and related compounds, (for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and pushes the pro-drug into the cytosol. The results suggest that the pro-drugs diffuses through human skin -100-130 times faster than do their parent drugs. It takes 2-4 hours for naproxen, suprofen, a-methyl-(p-chlorobenzoyl)-5-methoxy-2-methylindole 3-acetic acid, flurbiprofen, carprofen, pranoprofen, benoxaprofen, alminoprofen, tiaprofenic acid, pirprofen, zaltoprofen, bermoprofen, loxoprofen, indoprofen, fenclorac, oxaprozin, fenbufen, orpanoxin, ketorolac, clidanac, and related compounds to reach the peak plasma level when they are taken orally, but these prodrugs only took about 40-50 minutes to reach the peak plasma level when they are taken transdermally. In plasma, more than 90% of these pro-drugs can change back to the drug in a few minutes. The prodrugs can be used medicinally in treating any NSAIAs-treatable conditions in humans or animals. The prodrugs can be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of NSAIAs, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrugs enable naproxen, suprofen, a-methyl-(p-chlorobenzoyl)-5 methoxy-2-methylindole 3-acetic acid, flurbiprofen, carprofen, pranoprofen, benoxaprofen, almino, profen, tiaprofenic acid, pirprofen, zaltoprofen, bermoprofen, loxoprofen, indoprofen, fenclorac, oxaprozin, fenbufen, orpanoxin, ketorolac, clidanac, and related compounds to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of NSAIAs. Another great benefit of trans dermal administration of these pro-drugs is that administering medication, especially to children, will be much easier.
Patent AU-2013206283-B2 (AU)
Title: Gaming machine
Inventor: MIZUE HAYATO
IPC: A63F13/00
Filed: 2013-06-06
Granted: 2014-01-16
Abstract: GAMING MACHINE In a gaming machine including a symbol region (31) where reels having symbols (33) are arranged in predetermined arrangement, so that the symbols (33) are displayed in an arranged manner in longitudinal and transverse directions, there are provided a reel control unit that independently controls movement and stop of each of the reels, such that the symbols (33) appearing in the symbol region (31) change and a winning determination unit that determines whether the symbols appearing on a valid line set to span the reels form a predetermined winning pattern, when each of the reels is stopped, layers are set in the symbol region, and in the gaming machine, at least one reel is disposed in each layer, a symbol group is provided in at least one specific reel arranged in a specific layer of the layers in such a manner that symbols capable of forming at least portion of the winning pattern are arranged in the symbol group, at least one of the symbols capable of forming at least portion of the winning pattern overlaps the other reel in the other layer different from the specific layer, and that the symbol group move integrally with the specific reel, the symbols that are disposed in the symbol group in the specific reel can be viewed from a player, and when the symbol group is stopped on the valid line, the winning determination unit make the symbols disposed in the symbol group be included in a determination target and determines whether the winning pattern is formed. 7 D :1E
Patent AU-2013220367-B2 (AU)
Title: Polysiloxane based block copolymers
Inventor: TIAN YUAN
IPC: C08F299/00
Filed: 2013-02-14
Granted: 2016-06-09
Abstract: The invention is directed to polysiloxane based block copolymers that comprise siloxane untis and units derived from diol compounds comprising at least one pendant oligomeric or polymeric group. The block copolymers according to the invention surprisingly allows any glassware used during its preparation to be washed cleaned with water. The block copolymer can be used in ophthalmic lenses, and may be useful in providing contact lens formulations which are water processable.
Patent AU-2013251211-B2 (AU)
Title: Method and apparatus for packing chromatography columns
Inventor: RAHN PETER CHARLES
IPC: G01N30/60
Filed: 2013-10-30
Granted: 2015-09-03
Abstract: A portable tubular chromatography column having a tubular body with an inner diameter with first and second ends covered by first and second end caps, respectively, comprising: a bed of chromato graphic media placed between a first and second frit all located inside the body; a piston abutting the first frit and exerting a predetermined pressure on the bed; an adjustable locking mechanism having a support fastened to the body and having a threaded adjuster interposed between the support and the piston, such that rotation of the threaded adjuster increases or decreases the force the piston exerts on the bed. P/00/0 i l -CA
Patent AU-2013260930-B2 (AU)
Title: Production method of multiple panes
Inventor: ABE HIROYUKI
IPC: C03C27/06
Filed: 2013-05-16
Granted: 2016-06-02
Abstract: Provided is a manufacturing method that, despite being a simple process, makes it possible to manufacture multiple-pane glass that has no protrusions protruding from the outside surfaces of glass sheets. In this method for manufacturing multiple-pane glass, the periphery of a pair of glass sheets (2, 3) that are disposed opposite each other with a prescribed separation therebetween is sealed using a sealing material (4), forming between the glass sheets a space (A) that can be made airtight, and the pressure inside said space is reduced by evacuating the air therefrom via an evacuation port (7). After the pressure inside said space has been reduced, a region-forming material (5) disposed inside said space partitions said space into an evacuation-port region (B) that contains the evacuation port and a reduced-pressure region (C) other than the evacuation-port region.
Patent AU-2013263767-B2 (AU)
Title: Apparatus and method of managing a plurality of objects displayed on touch screen
Inventor: LEE SEUNG-MYUNG
IPC: G06F3/0484
Filed: 2013-11-28
Granted: 2019-01-31
Abstract: A method and an apparatus of managing a plurality of objects displayed on a touch screen are provided. The method includes determining whether at least two objects of the plurality of objects have been touched simultaneously on the touch screen, determining whether at least one of the at least two objects has moved on the touch screen, if the at least two objects have been touched simultaneously, determining the distance between the touched at least two objects, if the at least one of the at least two objects has moved on the touch screen, combining the touched at least two objects into a set, if the distance between the touched at least two objects is less than a predetermined value, and displaying the set on the touch screen. 4910703_1 (GHMatters) P95595.AU 28/11/13 DISPLAY PLURAL OBJECTS ON TOUCH SCREEN OF MOBILE DEVICE S502 AT LEAST NO TWO OBJECTS TOUCHED BY INPUT MEANS? MOVEMENT NO COMMAND INPUT FOR AT LEAST ON OF TOUCHED OBJECTS? MOVE AT LEAST ONE OF TOUCHED OBJECTSONTOUCH SCREEN 508 TOUCHED OBJECTS CONTACT? NO CHANGE SHAPES OF TOUCHED OBJECTS S512 TOUCHED NO OBJECTS WITHIN PREDETERM IN ED DISTANCE? DISPLAY TOUCHED OBJECTS IN S516 COMBINATION AS SET
Patent AU-2013271849-B2 (AU)
Title: Multi-word autocorrection
Inventor: WILLMORE CHRISTOPHER P
IPC: G06F17/27
Filed: 2013-06-03
Granted: 2016-05-12
Abstract: Methods and systems of multi-word automatic correction ("autocorrect") are provided. Autocorrect generally can select a corrected word based on a typed word and a dictionary of correctly- spelled words. Multi-word autocorrect can add to this functionality by revisiting the selection of an initial corrected word if a subsequently-typed word indicates that it would be more appropriate to instead select an additional corrected word. In some cases, an autocorrect system can make a multi-word correction based on a multi-word phrase in a dictionary, such as replacing "new york" with "New York" as described above. In other cases, an autocorrect system can make a multi-word correction to correct a mistakenly-typed delimiter character. In other cases, an autocorrect system can use grammar rules to obtain additional context information with each subsequently-typed word and make multi-word corrections on that basis.
Patent AU-2013280779-B2 (AU)
Title: Dimethyl-benzoic acid compounds
Inventor: BLANCO-PILLADO MARIA-JESUS
IPC: C07D401/04
Filed: 2013-06-20
Granted: 2015-09-10
Abstract: The present invention provides a compound of the Formula II: wherein A is: * R
Patent AU-2013349928-B2 (AU)
Title: Pesticidal mixtures
Inventor: BRAHM LUTZ
IPC: A01N63/30
Filed: 2013-11-12
Granted: 2017-04-13
Abstract: The present invention relates to pesticidal mixtures comprising one biological compound selected from the group consisting of Beauveria bassiana PPRI 5339, Metarhizium anisopliae FI-1045, Metarhizium anisopliae var. acridum FI-985 and Metarhizium anisopliae var. acridum IMI 330189 and one fungicidal or insecticidal or plant growth regulating compound and respective agricultural uses thereof.
Patent AU-2014200327-B2 (AU)
Title: Pneumatic tyre
Inventor: FUJITA MASAYUKI
IPC: B60C11/03
Filed: 2014-01-20
Granted: 2017-04-20
Abstract: PNEUMATIC TYRE Abstract A pneumatic tyre includes a tread portion (2) provided with a tread pattern with a designated rotational direction (N). The tread pattern includes a plurality of V-shaped main inclined grooves (3) that protrude toward the rotational direction and extend from one tread edge (Te) to the other tread edge (Te), a pair of connecting grooves (4) disposed both sides of a tyre equator (C) between the circumferentially adjacent main inclined grooves, and a center block (5) divided among the circumferentially adjacent main inclined grooves and the one pair of connecting grooves. The center block has a trapezoidal-like shape that comprises a laterally extending leading edge (9) and a laterally extending trailing edge (10) having an axial length larger than that of the leading edge. 3a 5 3a
Patent AU-2014200490-B2 (AU)
Title: Cooking release sheet materials and release surfaces
Inventor: WOERNER GRAHAM A
IPC: A47J27/00
Filed: 2014-01-30
Granted: 2015-07-16
Abstract: A cooking release material includes a layer comprisig fhuompolymer. The cooking release material has a major sauce having nucleation suctures in a density otat lkast 10 per squreinch. The co0ki ngreleas matena can clde a rn eentte the laycr coa*ted over the enforcement material. The cooing rease matel can iClude a second layer fOrming the major surface.
Patent AU-2014201061-B2 (AU)
Title: Detachable cargo transport board and container-platform dual-purpose rail wagon
Inventor: YI YONGFENG
IPC: B61D3/20
Filed: 2014-02-27
Granted: 2016-06-09
Abstract: The present application provides a detachable cargo transport board and a container-platform dual-purpose rail wagon. The transport board includes a board body, and multiple annular sleeves, each configured to cooperate with a locking member on each chassis unit of a container rail wagon, are fixed on the board body. The detachable cargo transport board according to the present application may be directly placed on the chassis of the container rail wagon, and in this way, the improved container rail wagon may be used as a platform rail wagon. The movement of the transport board with respect to the chassis may be confined by the cooperation between the annular sleeve and the locking member on the chassis unit. The switching between a container wagon and a platform wagon may be realized by dissembling and assembling the transport board, thereby obtaining a dual-purpose rail wagon. Thus the idleness rate or transportation with empty container may be reduced, and the utilization efficiency of the wagon is improved. The detachable cargo transport board has a simple structure and can be mounted quickly, thereby saving modification time and cost. 5155712 _1 (GHMatters) P96368.AU 27/02/14 Figure 4 30 10 302 302 Figure 5 100 30 30 100 30 100 Figure 6 5155712 _1 (GHMatters) P96368.AU 27/02/14
Patent AU-2014201338-B2 (AU)
Title: Flex cable and spring-loaded tube for tacking device
Inventor: WENCHELL THOMAS
IPC: A61B17/00
Filed: 2014-03-11
Granted: 2018-01-04
Abstract: FLEX CABLE AND SPRING-LOADED TUBE FOR TACKING DEVICE A surgical fastener applier (1000) is disclosed and includes a handle portion (100), a tubular member (200) extending from the handle portion (100) and defining a longitudinal axis ("A"), a drive member (240) rotatably supported in the tubular member (200) and in the handle portion (100), and a plurality of fasteners (300). The drive member (240) is configured to rotate while in a deflected condition with respect to the longitudinal axis ("A"). The drive member (240) includes a proximal portion (212), a central portion (244), and a distal portion (214), the central portion (244) being relatively more flexible configuration as compared to at least one of the proximal portion (212) and the distal portion (214). The plurality of fasteners (300) is disposed within the tubular member (200) and is configured to engage a portion of the drive member (240) such that rotational motion of the drive member (240) causes distal advancement of at least one fastener of the plurality of fasteners (300) through the tubular member (200). RI'l
Patent AU-2014203477-B2 (AU)
Title: Methods and devices for catheter advancement and delivery of substances therethrough
Inventor: SERINA EUGENE
IPC: A61M31/00
Filed: 2014-06-26
Granted: 2016-09-01
Abstract: Methods and devices for successively advancing a plurality of catheters over a guide element to a body tissue are described. In some of the methods, the guide element may be attached to the body tissue, which may be accessible minimally invasively. In certain variations, the guide element may not be detached from the body tissue after the catheters have been advanced over the guide element. The methods may further comprise deploying at least one implant from at least one of the plurality of catheters. In some variations, a method may comprise advancing a first delivery catheter to a first region of body tissue, deploying a first anchor from the first delivery catheter, where the first anchor is attached to a guide element, proximally withdrawing the first delivery catheter, advancing a second delivery catheter over the guide element, and deploying a second anchor from the second delivery catheter. 420 FIG. 4G 420 422 FIG. 4H 420 42 FIG. 41
Patent AU-2014228017-B2 (AU)
Title: Non-peptide BDNF Neurotrophin mimetics
Inventor: LONGO FRANK M
IPC: A61P25/28
Filed: 2014-03-14
Granted: 2018-08-30
Abstract: Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule.
Patent AU-2014236005-B2 (AU)
Title: Retail item management using wireless sensor networks
Inventor: RASBAND PAUL BRENT
IPC: G06K19/077
Filed: 2014-03-19
Granted: 2019-05-02
Abstract: A system for identifying handling events of an item is provided. The system includes at least one wireless sensor node, WSN, tag associable with the item. The WSN tag includes a transceiver and at least one sensor. The at least one sensor is configured to generate sensor data based at least in part on motion of the wireless sensor node. The WSN tag includes a memory configured to store at least one event filter and the sensor data. The WSN tag further includes a tag processor that is configured to filter the sensor data based on the at least one event filter. The tag processor is configured to determine whether an event occurred based on the filtering of the sensor data and generate even t data in response to determining an event occurred. The tag processor is configured to cause the transceiver to transmit the event data.
Patent AU-2014289059-B2 (AU)
Title: Novel salt of 3-[(3-{[4-(4-morpholinylmethyl)-1H-pyrrol-2-yl]methylene}-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl]-1,3-thiazolidine-2,4-dione, preparation thereof and formulations containing same
Inventor: LE FLOHIC ALEXANDRE
IPC: A61K31/5377
Filed: 2014-07-11
Granted: 2017-05-25
Abstract: The invention relates to a novel salt of 3-[(3-{[4-(4-morpholinylmethyl)-1H-pyrrol-2-yl]methylene}-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl]-1,3-thiazolidine-2,4-dione methanesulfonate having formula (II).
Patent AU-2014298172-B2 (AU)
Title: Apparatus for aligning radiation beams
Inventor: STACEY CRAIG DANIEL
IPC: G02B26/08
Filed: 2014-07-24
Granted: 2018-07-12
Abstract: Apparatus for co-aligning a plurality of laterally displaced radiation beams, each beam comprising a respective waveband, is disclosed. The apparatus comprises a collimating element for receiving each of said radiation beams with respective lateral displacements and a combining element for receiving each of said radiation beams passed by said collimating element to cause the radiation beams to become co-aligned. At least one of the collimating element and the combining element comprises an anti-reflection layer for minimising reflection of the radiation beams from the at least one element. The layer comprises an array of microstructured protuberances which extend away from at least a portion of a surface of the respective element, and which comprise a cross- sectional area which reduces along the length thereof, from a proximal end of the protuberance disposed proximate the surface to a distal end of the protuberance.
Patent AU-2014311608-B2 (AU)
Title: Swimming pool cleaner
Inventor: RIEF DIETER J
IPC: F04D29/00
Filed: 2014-08-21
Granted: 2018-07-05
Abstract: Disclosed herein are a steering system for a suction cleaning device, a locomotion system for a pool cleaner, and a turbine for use in an automatic cleaner. The steering system includes a fluid driven turbine that rotates a cam gear that is interconnected with a cam wheel for directing a drive pinion. The drive pinion is positionable in a plurality of positions to drive a nose cone that steers the suction cleaning device. The locomotion system includes first and second A-frame arms that respectively engage first and second bearings about first and second eccentrics of a turbine. Rotation of the turbine causes the first and second A-frame arms to rotate back and forth driving associated walking pod assemblies. The turbine includes a turbine rotor and a plurality of vanes connected to the turbine rotor. The plurality of vanes including lateral edges having lateral open regions to facilitate debris-removing efficiency.
Patent AU-2014363792-B2 (AU)
Title: Pharmaceutical compositions comprising dimethyl fumarate
Inventor: PLANELLS JIMENEZ MARIA
IPC: A61K9/28
Filed: 2014-12-05
Granted: 2019-11-14
Abstract: Pharmaceutical compositions are described comprising (a) dimethyl fumarate, (b) a diluent selected from monosaccharides, disaccharides, starch and starch derivatives, calcium and magnesium inorganic salts, sugar alcohols, and mixtures thereof, (c) microcrystalline cellulose and (d) croscarmellose sodium, wherein the dimethyl fumarate is not covered with a gastro-resistant coating. These compositions are intended for the treatment of some inflammatory autoimmune diseases or disorders.
Patent AU-2014364805-B2 (AU)
Title: Anti-CD3 antibodies and methods of use
Inventor: CHEN XIAOCHENG
IPC: C07K16/30
Filed: 2014-12-17
Granted: 2020-01-16
Abstract: The disclosure provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
Patent AU-2014402801-B2 (AU)
Title: Multi-zone actuation system using wellbore projectiles and flapper valves
Inventor: WALTON ZACHARY WILLIAM
IPC: E21B34/06
Filed: 2014-08-07
Granted: 2017-09-07
Abstract: An example sliding sleeve assembly includes a body that defines an inner flow passageway and one or more ports. One or more sensors are positioned on the body to detect wellbore projectiles that traverse the inner flow passageway, and a sliding sleeve is arranged within the body and movable between a closed position, where the sliding sleeve occludes the one or more ports, and an open position, where one or more ports are exposed. A flapper valve is arranged within the body and movable between an open configuration, where the flapper valve allows fluid flow through the inner flow passageway, and a closed configuration, where the flapper valve seats against a flapper seat defined on the sliding sleeve and prevents fluid flow through the inner flow passageway. An actuation sleeve is arranged within the body and movable to allow the flapper valve to move to the closed configuration.
Patent AU-2014412583-B2 (AU)
Title: Polar code rate matching method and apparatus, and wireless communications device
Inventor: SHEN HUI
IPC: H04N19/00
Filed: 2014-11-27
Granted: 2018-09-06
Abstract: Disclosed are a rate matching method and apparatus for a polar code, and a wireless communication device. The method comprises: according to the code length of a target polar code, and based on a Mason reversal algorithm, determining a first sequence; according to a pre-set rule, performing sort processing on the first sequence, to determine a second sequence; according to the first sequence and the second sequence, determining a mapping function; and according to the mapping function, interleaving the target polar code, to generate an interleaved output bit. By means of the rate matching method and apparatus for a polar code, and the wireless communication device in the embodiments of the present invention, by applying a Mason reversal algorithm to rate matching of a polar code, a structure of a bit sequence after the rate matching is caused to be more uniform, and a frame error rate of a punctured polar code can be reduced and the HARQ performance is improved, thus improving the reliability of communications. In addition, the present invention can be applied to a rate matching process for polar codes with various code lengths, which has good universality and practicability.