baber/WOPTO huggingface dataset:
Patent EP-4286415-A2 (EP)
Title: Humanized antigen-binding domains against cd19 and methods of use
Inventor: WILTZIUS JED J W
IPC: C07K16/28
Filed: 2018-04-24
Abstract: The invention provides a humanized anti-CD 19 antibody or antigen binding fragment thereof comprising a light chain variable (VL) region and a heavy chain variable (VH) region in which the humanized VL and VL regions are derived from the mouse anti-CD 19 clone FMC63 antibody; the humanized VL and/or humanized VH region comprise one or more amino acid substitutions in the framework region. The humanized anti-CD 19 antibody or antigen binding fragment may be part of a single chain variable fragment (scFv), a chimeric antigen receptor (CAR) or a T cell receptor (TCR). Other aspects of the invention relate to cells comprising the CAR or the TCR and their use in a T cell therapy.
Patent EP-4299095-A2 (EP)
Inventor: LEROUX JEAN
IPC: A61M16/00
Filed: 2022-02-10
Abstract: L'invention concerne un appareil à toux pour opérer des insufflations et exsufflations de gaz à un patient, comprenant une turbine motorisée et un circuit de gaz avec des lignes d'insufflation et d'exsufflation, un écran d'affichage (20), et des moyens de pilotage configurés pour commander la turbine et/ou l'affichage sur l'écran d'affichage (20) d'une animation vidéo mettant en oeuvre une première représentation graphique (30) symbolisant au moins les phases d'insufflation et d'exsufflation de gaz et une seconde représentation graphique (40) symbolisant le patient. Les dimensions des première et seconde représentations graphiques affichées sur l'écran d'affichage varient en corrélation et inversement les unes aux autres, avec les phases d'insufflation et d'exsufflation de gaz de manière à assister le patient pendant son traitement, en particulier en mode INEX. L'aspect et/ou la forme des première et/ou seconde représentations graphiques peuvent aussi varier en corrélation avec les phases d'insufflation et d'exsufflation de gaz.
Patent EP-0005082-A2 (EP)
Inventor: SEMP BERNARD ALBERT
IPC: C02F3/34
Filed: 1979-04-25
Abstract: A process for the reduction of the nitrate-nitrogen content of tobacco by microbial treatment is disclosed. Tobacco materials are subjected, under controlled conditions, to the action of a microorganism effective in its ability to degrade nitrates through biochemical reactions in which nitrogen gas is ultimately formed. The process is applicable for all types of tobacco materials such as tobacco filler, aqueous tobacco extracts, stems, and tobacco processing streams from various reconstitution processes, as well as tobacco processing effluent. Tobacco materials treated in accordance with this process, when incorporated into a tobacco smoking product, have been found to deliver a significantly reduced amount of oxides of nitrogen in the smoke.
Patent EP-0017226-A2 (EP)
Title: Hinge
Inventor: KALTENPOTH ULRICH
IPC: E05D3/06
Filed: 1980-04-02
Abstract: The subject on which the invention is based is to provide a hinge of simple manufacture and mounting and to ensure its cyclic movement, the mutually associated upper edges of parts connected pivotally to one another by means of the hinge being at a sufficient distance from one another in every phase of movement. This is achieved, according to the invention, in that the angle levers (5, 6) are of essentially U-shaped form, their long legs (8) are directed obliquely outwards and the guide tracks (11) are so designed that these are subdivided into three regions (12, 13, 14), the middle (12) of which extend approximately horizontally, whilst the inner (13) and outer (14) regions have inclinations directed obliquely downwards. The hinge is provided with indentations in the middle parts of the middle regions (12) of the guide tracks (11), the degree of the inclinations of the inner (13) and outer (14) regions of a guide track (11) being of different amounts. The degree of the inclinations of the outer regions (14) of the guide tracks (11) is greater than that of the inner regions (13).
Patent EP-0031432-A2 (EP)
Inventor: COX ALLEN RONALD
IPC: G11B5/105
Filed: 1980-11-14
Abstract: A magnetic head mount assembly for accessing data tracks recorded on a magnetic medium includes a mounting post (10), an arm (16) which supports the post in close-fitting engagement, and a yoke (18) on which printed circuit connections are disposed. An end portion of the post is slotted (28a, 28b) to receive electrical leads (22) for connection to a ferrite magnetic transducer core (24) which forms part of an otherwise ceramic air bearing slider (26) positioned over the slotted end portion of the post. The arm element is preferably of hollow frusto-conical form.
Patent EP-0023166-A2 (EP)
Inventor: ADES HENRI
IPC: G09F7/02
Filed: 1980-06-30
Abstract: Display device of the type comprising a panel wherein grooves are provided to fixe removable signs. The hooking means (7) of the small plates (5 and 6) on which the signs are reproduced are comprised of ribs slightly diverging from their base and of which the apex have the shape of hooks. Due to the relative resilience of the constituent material, the setting in place or the removal of a small plate is easily effected. A notch (27) facilitates the removal and provides for a reference means for the sign direction. The ends of the panels (2 and 3) are provided so that they may be superposed by jointing (4) and made integral by any known means. Applications: signalling and information at any public place (train stations, airports, theatres, restaurants, hospitals, offices, etc... and private place (commercial and industrial premises, etc...).
Patent EP-0036063-A2 (EP)
Inventor: TREBER WILLI O
IPC: B60J10/70
Filed: 1981-01-14
Abstract: 1. A clip-fastenable edge mask (2, 2a) for a bonded vehicle window (4), comprising a clip (1, 1a) which - viewed in cross-section - is V-shaped or U-shaped, which spaced from further clips (1, 1a) is arranged to be located in the region of the window edge and to be held by the vehicle window (4) and a window frame (3) and at least one leg (6) of which is provided with one or more externally disposed lips (7, 7a), the lip, or one of the lips, being positioned in the vicinity of the clip's base (8) and arranged to claw behind the inserted vehicle window (4), the clip also being provided with further lips for clippingly fastening the edge mask (2, 2a), characterized in that the edge mask (2, 2a) is provided with a web (13) extending from its rear face, that the clip (1, 1a) forms with the space enclosed by its legs (6, 9, 9a) a slip-in aperture for receiving the web (13) of the edge mask (2, 2a), that for the purpose of retaining the edge mask's (2, 2a) web (13), which at its free end is provided with a barb (12), the inner face of the one leg (6) of the clip (1, 1a) is formed with a recess (11), and in that the angle of tilt of the other leg (9, 9a) exceeds that of the clip (1, 1a) at insertion.
Patent EP-0035280-A2 (EP)
Inventor: KUMMERMEHR HANS
IPC: H05B3/74
Filed: 1981-03-04
Abstract: 1. Apparatus for heat insulation of a heat source (5), especially of the electric heater coil for a radiant hot plate for a cooker, having a containing dish (1) for a heat insulating material (2) located between the heat source and the base (4) of the containing dish, which comprises at least on insulating layer (9) adjacent the base comprising a micorporous oxide aerogel formed by flame pyrolysis, especially silicic acid aerogel, with, if desired, mineral fibre reinforcement and/or filler is pressed directly into the dish and compresses there, characterized in that the insulating layer (9), has, on its sides facing away from the base (4), a concave - as seen from the heat source- surface (fused surface layer 10) and/or that the base (4) of the dish (1) - seen from below - is convex and/or that the inner face of the base (4) of the dish (1) has securing means for the material of the insulating layer (9), to such an extent that the insulating layer (9)  can in no circumstances bow upwardly after release of the pressure of the press member that presses in the material.
Patent EP-0056448-A2 (EP)
Inventor: LICHT HEINZ ING GRAD
IPC: H01R13/646
Filed: 1981-10-28
Abstract: The invention relates to a socket (1) for an antenna for two- directional transmission and for a fitment to the walls of buildings. The socket (1) for the antenna contains a first coaxial socket (2) for extraction of radio signals and a second coaxial socket (3) for extraction of TV signals. According to the invention, a third connection (4) is provided. This is used for the reception of signals in a reversed channel leading to a central station which are used, for example, for text and video distribution, an ordering service or monitoring (fig 1). <IMAGE>
Patent EP-0035292-A2 (EP)
Inventor: SHEFFORD ROGER ALAN
IPC: C08J7/048
Filed: 1981-02-05
Abstract: The present application relates to enclosure members consisting essentially of solid, non-aromatic polymers that have a linear carbon to carbon backbone structure and having a plurality of free hydrogen atoms attached to the carbon atoms with a permeability to wet solvents and fuels of less than 1/50, optionally less than 1/200 of the permeability of untreated enclosure members having a thickness of 1 mm. Said low permeability is due to the presence of a coating on at least the inner surface of said enclosure members, having a portion of the hydrogen atoms replaced by sulphonic acid or sulphonate groups, consisting of a cured thin layer (of at least 2 µm) of condensation products of formaldehyde and melamine of formaldehyde and urea. Evidently the application relates also to a method of preparing said enclosure members.
Patent EP-0036251-A2 (EP)
Inventor: GARRATT JOHN DAVID
IPC: G01B11/00
Filed: 1981-02-19
Abstract: A polarising interferometer wherein at least one of the two measuring arms (13,14) contains an optical cube corner (16 or 19) devoid of coatings on its reflecting surfaces and with its refractive index selected so that the resulting retardation and orientation of the principal axes causes the cube cornerto act as a X/4 plate, the beam through the uncoated cube corner being reflected back through a movable end reflector (18 or 20) insensitive to tilt and lateral movement so that the uncoated cube corner acts as a X/2 plate on double transmission, and phase difference in the output beams is detected by an analyser (23, 26, 28) forming four spatially separated component beams respectively polarised at differing azimuth angles, which give two outputs in phase quadrature, of equal amplitude and free of d.c. offsets. The uncoated cube corner acting as a λ/4 plate on single transmission and a λ/2 plate on double transmission also has application to other polarising optical systems, especially where a coated cube corner has hitherto been used.
Patent EP-0061718-A2 (EP)
Inventor: NARITA MASAHISA
IPC: B41J19/18
Filed: 1982-03-25
Abstract: The present invention relates to a serial printer comprising the mechanism for selecting one type (15b) by moving the mounted printing wheel (15) and the carrier (6) for moving said mechanism on the print sheet (42). It is an object of the invention that the printing can be done at the maximum speed which is the optimum for the print wheel (15) even in case any kind of printing wheel is mounted and is characterized in that the carrier shifting speed can be changed in accordance with the intertia of printing wheel (15) and a shifting distance of printing wheel.
Patent EP-0074666-A2 (EP)
Inventor: SONE JUNICHI
IPC: H03K19/195
Filed: 1982-09-14
Abstract: A logic gate circuit utilizing the Josephson effect is disclosed which has very short gate delay time and wide operational margins and is feasible for a high degree of integration. The circuit comprises a group of N (N ≥ 2) of parallel branches, each branch consisting of a series connection of resistor (R 11 , R 12 , R 13 ) and a Josephson junction (J 11 , J 12 , J 13 ), connected in parallel, a chain of series connected N-1 resistors (R 21 , R 22 ) each connecting the junction points of resistor and Josephson junction of two adjacent branches, and a further Josephson junction (J 3 ) connecting an input terminal with one end of said chain of resistors. Each resistor and each Josephson junction has a predetermined resistance and critical current, respectively.
Patent EP-0077020-A2 (EP)
Inventor: TAMURA MASAO
IPC: H01L21/268
Filed: 1982-10-06
Abstract: The whole surface of a polycrystalline or amorphous semiconductor film (5) disposed so as to continuously cover the surface of a single-crystal substrate (3) and an insulating film (4) is irradiated with a laser beam or electron beam, thereby to selectively melt only those parts (5') of the polycrystalline or amorphous semiconductor film which overlie the insulating film. Thus, a single-crystal semiconductor film is formed on only the Insular inslating film (4) formed on the single-crystal substrate (3).
Patent EP-0057094-A2 (EP)
Inventor: MEGNA SALVATORE
IPC: A45D1/00
Filed: 1982-01-22
Abstract: A curling iron (10) has a tubular body (14) with bristles (46) and a handle (12). The bristles (46) are fixed in four bars (44) within the body (14) and extend outward for reciprocating movement through wall openings (42). Four actuator pins (36,38) fixed to each of two supports (50,52) extend at an angle (a) to slidably engage the bars (44) and move them radially when the supports (50,52) are moved together longitudinally by a slidably mounted tie rod (58). Four guide pins (48) fixed to the body (14) restrain longitudinal movement of the bars (44). An external manually operable sleeve (54) on the body (14) engages one support (52) for moving the supports (50,52) for retraction of the bristles (46), and a spring (100) biases the support (52) for automatic return to a position with the bristles (46) extended.
Patent EP-0098492-A2 (EP)
Inventor: ACKERT ROBERT JAMES
IPC: B21B15/00
Filed: 1983-06-27
Abstract: Railroad rails having improved wear resistance, are produced by controlled forced cooling from above the austenite transformation temperature, to produce rails having a fine pearlite metallurgical structure in the head portions (6) of the rails. Apparatus comprising a series of cooling headers (la, 1b) utilizing a liquid cooling medium, such as unheated (i.e. cold, or ambient temperature) water, alternating with a series of air zones (2a, 2b), is preferably arranged in line with the production rolling mill, to receive hot rails as they emerge from the mill, without the necessity of intervening reheating. A roller type restraint system (9) transports the rails through the cooling apparatus, while restraining them in the appropriate position. Each segment of the rail length is intermittently subjected to forced cooling by spray application of the liquid cooling medium, applied to the head portion (6) and the central portion of the base bottom (7) of the rail, with means being provided to prevent spray from impinging on the web and base tips of the rail: During the intervals between applications of forced cooling, heat soaks back from the web portion (4) of the rail, the operating parameters of the system being so arranged that the temperature of the rail remains essentially above the martensite formation temperature. A computerized control system discontinues the application of forced cooling, at a predetermined stop temperature, also above the martensite formation temperature. The apparatus and method are capable of producing rails having the desired fine pearlite structure in the head portion, on a consistent basis, notwithstanding wide variations in temperature between different rails, and different segments of the same rail, as they emerge from a conventional production rolling mill.
Patent EP-0128291-A2 (EP)
Inventor: ROBERTSON DAVID BRUCE
IPC: G09G5/36
Filed: 1984-04-05
Abstract: A word processing system is provided with separate data structures in system memory (4). One of these, the internal image, contains the calculated graphics image and another the operator's alphanumeric character input. When displaying, the two images are merged together with the annotation overlay effectively overlying the graphics overlay. In this way, if the operator erases something on the annotation overlay, the contents of the graphics overlay reappear. During the display of the calculated image and as the operator adds annotations to the display, conflicts between the graphics image and an alphanumeric character added by the operator are resolved in favor of the alphanumeric character. When a conflict does exist, the alphanumeric character is highlighted by video reversing to indicate that it is hiding a portion of the graphics image.
Patent EP-0151209-A2 (EP)
Inventor: DIETERICH ARTUR
IPC: E05D15/26
Filed: 1984-04-28
Abstract: With the exception of the one inwardly pointing door leaf 2, all the door leaves 3,4 of the multiple-leaf door of a portal 1 are suspended in pairs by in each case one supporting carriage 26, which moves along in a supporting rail 27 anchored above the portal. The outermost door leaf 4 of the multiple-leaf door is constructed as a swinging door. A closing element 19 which is fastened to the supporting carriage is provided for this swinging door. <IMAGE>
Patent EP-0140034-A2 (EP)
Inventor: TAKAGI KUNIHIKO
IPC: H02B13/055
Filed: 1984-09-03
Abstract: @ An adsorption device is provided for adsorbing decomposed gas and the like produced in a gas-insulated electric apparatus. The adsorption device has an enclosed casing for encasing an adsorbent, which is secured internally, externally, or outwardly in a spaced apart relation to one wall of said apparatus housing. Valve means are provided in inlet and outlet portions of said casing, and an access port for replacing the adsorbent is provided for said casing to be normally closed by a detachable cover plate.
Patent EP-0149841-A2 (EP)
Inventor: JESCHKE WILLI
IPC: B41F31/00
Filed: 1984-12-22
Abstract: It is assumed that the inking unit constituting the means for carrying out the method has, at most, two inking rollers of equal diameter which are assigned to the forme cylinder and to which an inking duct roller is assigned, and a relatively thick ink film from a zoneless metering device is reduced by means of an inking roller chain, and the printing forme is inked with a thin uniform ink film by means of the inking duct roller and the inking rollers. <IMAGE>
Patent EP-0119802-A2 (EP)
Inventor: SUGIURA SATOSHI C O PATENT DIV
IPC: A61B5/055
Filed: 1984-03-09
Abstract: A nuclear magnetic resonance diagnostic apparatus is described which has means (2) for generating high frequency pulses to be applied to an object to excitate nuclear magnetic resonance, the pulses being synchronisable with a cyclic noise component in the signal receiving system; means (9) for applying said high frequency pulses to the object and detecting the nuclear magnetic resonance signals evoked from the object; means (1) for phase demodulating the nuclear magnetic resonance signals received by said detecting means; means (2) for generating reference signals of the same frequency as, and synchronised with, the excitation pulses; means (12) for changing the phase of the reference signals generated by the reference signal generating means to provide first and second reference signals differing in phase 180°; means (13) for applying selectively the said first and second reference signals to said phase demodulation means; means (7) for inverting selectively the demodulated outputs obtained by said phase demodulation means; and means (7) for adding corresponding pairs of inverted and non-inverted signals of the demodulated outputs to eliminate the cyclic noise component.
Patent EP-0123491-A2 (EP)
Inventor: NILSSON VILGOT
IPC: B04B1/10
Filed: 1984-04-16
Abstract: A centrifugal separator for separating two liquid components from each other has normally continuously open outlets for both liquid components, an interface layer formed in the separating chamber between the separated liquid components being maintained at a predetermined radial level. The present invention concerns a special arrangement for continuous discharge of the light liquid component but intermittent discharge of the heavy liquid component. For this purpose a first outlet channel (20) in the centrifuge rotor for the heavy liquid component communicates through a calibrated opening (24) with a stationary second channel (23) outside the rotor, said second channel comprising a shut off valve (31). Sensing equipment (28) is arranged to sense when an interface layer formed in the separating chamber (8) of the rotor between the separated liquid components has moved radially inwards to a certain level (29), and provides a signal to a control unit (34) which opens the valve (31) for a time to allow the desired amount of heavy liquid component to be discharged from the separating chamber (8).
Patent EP-0142391-A2 (EP)
Inventor: SCHNEIDER GUENTER
IPC: G11B5/596
Filed: 1984-09-04
Abstract: The present invention employs, in a preferred embodiment, a pair of pulleys, one of which is fixed (11) and the other of which is movable (13) and each of which has substantially the same diameter. The pulleys each have an axial aperture which holds a bearing arrangement including a shaft. Mounted across the two shafts (15,17) is a pair of plates (19,20) which are interconnected and therefore act together as a rigid body. The rigid body, or rigid member, is movable in a rotary fashion. In addition, there is a flexible band member (23) which loops a substantial section of the movable pulley and, in a preferred embodiment, is disposed to come in frictional contact with the movable pulley and the fixed pulley. The ends of the band are secured to the fixed pulley and are held in tension. Accordingly, as the plates (19,20) (the rigid body) are moved in a rotary fashion around the center of the fixed pulley, the movable pulley is moved, relative to its associated shaft, in a counter direction in response to the friction force between the band (23) and the movable pulley (13). Hence, in the preferred embodiment, the movable pulley (13) effects a curvilinear translation. The read/write head assembly is moved radially across a plurality of tracks of a magnetic disk (40). In this way, the change in yaw, or skew, between the read/write head (39) and the tracks on the magnetic disk (40) is held to a minimum.
Patent EP-0154194-A2 (EP)
Inventor: ZOK URSULA
IPC: A63H9/00
Filed: 1985-02-08
Abstract: The moulded toys concerned are, in particular, dolls' heads comprising a soft body and a textile skin. A seamless, finished felt or knitted fabric web is subjected to heat in a mould comprising male part and female part and shaped into a profiled textile skin simulating the model of part of the moulding to be produced, the profiled textile skin is supported in an open negative mould simulating the same part-model and the opening of the negative mould is closed by a shell mould completing the shape of the moulding to be produced and the mould cavity is foam-filled with a reaction mixture which is introduced into the mould cavity in the area of the completing shell mould. <IMAGE>
Patent EP-0157142-A2 (EP)
Inventor: WERTH DEE ADOLPH
IPC: H01R13/658
Filed: 1985-02-19
Abstract: ® A continuous 360° electrically conductive seal about the back shell (30) of an electrically conductive connector shell (20) having teeth extending aftwardly from its end face (34) and around the braid shield (46) of a coaxial-type cable (40) connected to the back shell by an accessory boot (50) protects signal carrying conductors from EMI entry and the surrounding area from EMI leakage. A frusto-conical wall including an electrically conductive annular wall portion, such as provided by the inner wall (100) of an accessory ferrule (56), or of an electrically conductive annular cap (68, 78, 86) mounted in the ferrule is interference fit about the toothed end face of the connector shell so as to overlap and completely encircle the back shell at a point inwardly of the valleys (36) of the teeth.