baber/WOPTO huggingface dataset:
Patent EA-003753-B1 (EA)
Title: Method for producing 1-substituted 5- or 3-hydroxypyrazoles
Inventor: MAYWALD VOLKER
IPC: C07D231/20
Filed: 1999-11-06
Abstract: 1. A process for preparing a 1-substituted 5- and/or 3-hydroxypyrazole of the formulae I and II, respectively in which R<1> is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl or C1-C4-alkoxy, where these groups may be substituted by halogen, C1-C4-alkoxy, phenoxy, C1-C6-alkoxycarbonyl, C1-C6-alkylthiocarbonyl or by a cyclic ring system having 3-14 ring atoms, which comprises reacting c) an alkyl vinyl ether of the formula V in which R<2> is C1-C6-alkyl or C3-C6-cycloalkyl with phosgene VIa, "diphosgene" VIb or "triphosgene" VIc to give an acyl chloride of the formula VII d) converting this by elimination of hydrogen chloride into the corresponding 3-alkoxyacryloyl chloride of the formula VIII and e) esterifying this with an alcohol of the formula IX in which R<3> is C1-C6-alkyl or C3-C6-cycloalkyl to give the corresponding alkyl 3-alkoxyacrylate of the formula III, and reacting said alkyl 3-alkoxyacrylate of the formula III with a hydrazine of the formula IV in which R<1> is as defined above a) at a pH of 6-11 to give 5-hydroxypyrazoles of the formula I or b) at a pH of 11-14 to give 3-hydroxypyrazoles of the formula II. 2. A process as claimed in claim 1, wherein the reaction in step a) is carried out at from -30 degree C to 100 degree C. 3. A process as claimed in claim 1, wherein the reaction is carried out in the presence of a base. 4. A process as claimed in claim 1, wherein the base used is an alkali metal hydroxide, alkaline earth metal hydroxide or tertiary amine. 5. A process as claimed in claim 2, wherein a solvent is initially charged and the alkyl 3-alkoxyacrylate III and the hydrazine IV are simultaneously metered into the solvent. 6. A process as claimed in claim 5, wherein the solvent used is water, an alcohol, ether or a mixture of these. 7. A process as claimed in claim 1, wherein the reaction in step b) is carried out at from -30 degree C to 100 degree C. 8. A process as claimed in claim 7, wherein the reaction is carried out in the presence of a base. 9. A process as claimed in claim 8, wherein the base used is an alkali metal hydroxide, alkaline earth metal hydroxide, a tertiary amine or a mixture of these. 10. A process as claimed in claim 1, wherein the reaction in step c) is carried out at from -78 degree C to 100 degree C. 11. A process as claimed in claim 1, wherein the alkyl vinyl ether V is reacted with phosgene VIa, diphosgene VIb or triphosgene VIc in a molar ratio of from 0.1:1 to 1:1. 12. A process as claimed in claim 1, wherein the reaction in step d) is carried out at from 30 degree C to 80 degree C. 13. A process as claimed in claim 1, wherein the esterification in step e) is carried out at from -20 degree C to 80 degree C.
Patent EA-006164-B1 (EA)
Title: Use of extracts of the genus cimicifuga as organoselective medicines for treating genitourinary system disorders caused by sex hormones
Inventor: WUTTKE WOLFGANG
IPC: A61P15/00
Filed: 2002-09-16
Abstract: The invention concerns genus Cimicifuga extracts, and in particular of Cimicifuga racemosa, which are suitable for producing a pre-formulated agent for selectively treating and/or preventing diseases of the genitourinary system caused by sex hormones. Furthermore, the inventive extracts are suitable for treating and/or preventing post-menopausal infections of the bladder, and for treating benign and malign prostatic hypertrophy.
Patent EA-011014-B1 (EA)
Title: Heating and air-conditioning device
Inventor: SCHREIBER BERNHARD
IPC: F24F1/0323
Filed: 2004-09-24
Abstract: The invention relates to a device which can be used alternatively to heat and air-condition a space, such as a residential, working or storage premises or room or any other enclosed area.The inventive device consists of: a heating unit (1) comprising a closed firebox (2) and an air circuit which is used to release the calories produced by said closed firebox (2); and an optionally-reversible air-conditioning unit comprising at least two exchangers including an inner exchanger which is placed in an inner air circuit that communicates with the exterior by means of the aforementioned calorie-releasing air circuit in order to diffuse the air from inside the device externally. In addition, at least one of the exchangers is placed upstream and, preferably, at the outlet of the air circuit which is connected to the closed firebox (2).In this way, at least one air flow can be obtained at a suitable temperature and cooled if necessary, e.g. during hot periods, and additional calories or frigories can be permanently or occasionally supplied to the closed heating firebox, e.g. during cold periods.
Patent EA-009270-B1 (EA)
Title: Bill handling device
Inventor: YOSHIOKA KAZUEI
IPC: G07D11/00
Filed: 2006-06-16
Abstract: A bill processor includes a housing, a bill insertion slot, a bill transfer mechanism, a bill container and a bill pressing mechanism. The bill transfer mechanism transfers the bill inserted from the bill insertion slot and discharges the bill toward a bill pushing area positioned downstream. The bill pressing mechanism presses the bill discharged into the bill pushing area toward the bill container. The bill pressing mechanism includes a supporter attached to the housing, a pressing plate movable toward the bill container, a link member joining the supporter and the pressing plate. The link member has an opening and a moving member movable in the opening, and the moving member has a first end portion supported with respect to the supporter and a second end portion engaged with the pressing plate and movable with respect to the supporter.
Patent EA-011145-B1 (EA)
Title: Apparatus method and system for a data entry interface
Inventor: VAN DER HOEVEN STEVE
IPC: G06F3/023
Filed: 2005-03-11
Abstract: Apparatuses, methods and systems for the efficient entry of data on a device with a restricted set of input channels are disclosed. These apparatuses, systems and methods may employ a user interface which allows efficient entry of input. This interface may be tailored according to the device with which it is used, and the semantic meaning associated with the interface. To assist in the efficient entry of data, these apparatuses, systems and methods may disambiguate user input, provide an efficient way to specify the input exactly, or predict user input. These apparatuses, systems and methods may also adapt to the proclivities of a certain user, and incorporate user defined abbreviations and synonyms for frequently used inputs.
Patent EA-013341-B1 (EA)
Title: Choke valve device
Inventor: HUSVEG TRYGVE
IPC: B01D17/00
Filed: 2006-08-14
Abstract: An arrangement for a control valve (1) for controlling pressure and flow rate of a fluid, the fluid flowing via an inlet (16) into the control valve (1) being brought to rotate about a main flow axis (20) before the fluid, at least with reduced pressure or speed energy, flows via an outlet opening (12) from the control valve (1) and where at least one inlet port (14) communicating with the inlet (16) being provided tangentially in relation to an inlet portion (22) of the speed reduction chamber (6) located in the control valve (1), and where the speed reduction chamber (6), provided substantially concentric with the main flow axis (20), is divergent over at least the first portion of the main flow direction.
Patent EA-011787-B1 (EA)
Title: Compact fluorescent lamp
Inventor: LUCZENBACHER JAMES ISTVAN
IPC: H01J5/48
Filed: 2005-10-26
Abstract: Compact fluorescent lamp having a known base (1), a central hollow column (2), attached to the base (1), and the outer surface of which has a heat- and light-reflecting coating; a cap (3) closing the hollow column (2); and one or more light-radiating members (4) secured to the cap (3) and/or to the hollow column (2). The light-radiating members (4) start from the hollow column (2) and connect to electronic and electric elements and pass through the holes (3b) of the hollow column and/or the cap (3). The lamp further comprises a guide-ring (11) to support the light-radiating members (4) extending until or beyond the meeting boundary edge of the base (1) and the hollow column (2). The hollow column (2), the base (1), the cap (3) and the guide ring (11) are encompassed with the light-radiating members (4) extending in at least a direction parallel with the longitudinal axis of the lamp towards the base (1) and back and the light-radiating members (4) have curved sections (4a). The lamp is retrofit with conventional bulb sockets.
Patent EA-014538-B1 (EA)
Title: Method for mineralization of root tooth tissue
Inventor: DEDOVA LYUDMILA NIKOLAEVNA
IPC: A61K33/06
Filed: 2007-05-11
Abstract: The present invention relates to medicine, namely, dentistry, and may be used in the treatment of caries of a tooth root. The object of the invention is to improve the efficiency of remineralization of hard tooth tissues for the purpose of reducing treatment periods of progressive and/or rapidly progressive supragingival carious stains without dentine defects on the vestibular and/or oral surface of a tooth root. The method consists in the subsequent use, in the course of the medical treatment of demineralization of tissues of a tooth root for the purpose of cleaning a tooth root and for Ph normalization, of the following substances: sodium hydrogen carbonate; 0.01% Myramistin solution for suppressing the activity of pathogenic microflora and for enhancing focal defense reactions; calcium glycerophosphate and nanocrystalline calcium hydroxyappatite as remineralizing components, and finally a fluorinated photocurable dentine cylant (desensitizer) is applied for providing a long-term contact of the above medicaments with complex cavity of a tooth root and for reducing dentine sensitivity of exposed tooth roots. The affected surface of a tooth root is exposed to medicaments during 3 procedures for 2.5 minutes at one day interval.
Patent EA-015879-B1 (EA)
Title: Use of fungicides for increasing the quality and optionally the quantity of oil-plant products
Inventor: VANTIEGHEM HERVE R
IPC: A01G7/00
Filed: 2007-02-01
Abstract: The invention relates to the use of specific fungicides for increasing the quality and optionally the quantity of oil-plant products and to the use of said fungicides for reducing the brittleness of the seed coats of seed-oil plants. The invention also relates to oil-plant products obtained from oil plants that have been treated with said fungicides, e.g. oil or seeds from treated oil plants. The invention further relates to regenerative fuels, which contain the oil according to the invention and/or the conversion products thereof. Finally the invention relates to a method for improving combustion in motors and combustion plants, according to which the motors and plants are at least partly operated by a suitable oil-plant product, produced according to the invention.
Patent EA-017304-B1 (EA)
Title: Process for preparing heterocyclic derivatives
Inventor: BACCHI SERGIO
IPC: C07D401/04
Filed: 2007-03-30
Abstract: The present invention relates to a novel process, useful for preparing key intermediates of Formula (I) in the synthesis of various compounds, among them compounds which are potent and specific antagonists of D3 receptors. The compound of Formula (I) in which X is nitrogen; Het means aryl or heteroaryl (wherein aryl is an aromatic carbocyclic functional group, such as phenyl, biphenyl or naphthyl, and heteroaryl is a mono- or bicyclic aromatic heterocyclic ring having from 5 to 10 members and having at least one hetero atom selected from nitrogen, oxygen and sulphus), each of which may be substituted by 1 to 4 groups J, selected from halogen, C-Calkyl, C-Calkoxy, halo C-Calkyl, C-Calkenyl, C-Calkynyl, halo C-Calkoxy, -C(O)R, nitro, hydroxy, -NRR, cyano; Ris a C-Calkyl, -OR; Ris hydrogen or C-Calkyl; Ris hydrogen or C-Calkyl; R is H, C-Calkyl, aryl, benzyl; each of which may be substituted by 1 to 4 groups J; is obtained according to the following Scheme:in which step a means a reaction in basic conditions of compounds (NA) with 3- thiosemicarbazide derivatives; step b means a treatment with an inorganic base and n-propane phosphonic cyclic anhydride to reach basic pH value; stage c means final pH adjustment with 4-8 inorganic acids to give compounds of formula (II).
Patent EA-015191-B1 (EA)
Title: Shock-absorbing device
Inventor: GOLOVACH RUSLAN NIKOLAEVICH
IPC: F16F7/09
Filed: 2009-02-27
Abstract: The invention relates mainly to apparatuses of impact energy absorption for use in carriages and locomotives aimed at reducing longitudinal forces, working in a train at hitting of carriages. The inventive task is aimed at increasing of a shock absorbing device operation efficiency due to introduction of additional selective change the degree of absorption of the shock loading at its large and small values. The assigned task is characterized in that the shock-absorbing apparatus (fig. (2) comprising a multisurface body 1 with an internal friction surface, wherein the body includes friction wedges 4 together with a pressure wedge 3, the friction wedges being in contact with a support plate 5 located on a polymeric array, consisting of seriously arranged elastic blocks 6 separated by a laminated element 11 consisting of friction sectors with curved ends 14 positioned between the elastic blocks 6 and the inner friction surface 2 of the body 1. Moreover, it is preferable that the length of the friction surface 2 of the body 1 will exceed half of its length. An embodiment of the device provides increasing life-time of the curved ends of the friction sectors of the laminated element 11 making it corrugated, as well as applying an anti-friction coating on the side of the elastic blocks.
Patent EA-017333-B1 (EA)
Title: New process for the synthesis of 7,8-dimethoxy-1,3-dihydro-2h-3-benzazepin-2-one, and its application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
Inventor: LERESTIF JEAN-MICHEL
IPC: C07D223/16
Filed: 2009-06-19
Abstract: A process for the synthethis of a compound of formula (I)is used for the synthesis of ivabradine, its addition salts with a pharmaceutically acceptable acid.
Patent EA-015836-B1 (EA)
Title: A process for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl-2-naphtoic acid
Inventor: KALVINSH IVARS
IPC: C07C51/09
Filed: 2007-12-28
Abstract: A process for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid from 2-(1-adamantyl)-4-bromanisole is disclosed, based on transformation of 2-(1-adamantyl)-4-bromanisole into a Grignard's reagent by using metallic magnesium, anhydrous lithium chloride and dibromoethane followed by transmetalation with borates to 3-(adamantyl)-4-methoxyphenylboronic acid, which is converted into 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid esters by Suzuki-Miyaura cross-coupling reaction with alkyl-6-halonaftoates catalyzed by Pd [0] or Pd/phosphine ligands and followed by basic hydrolysis in ethylene glycol or 1,2-propanediol of ester thus obtaining 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid.
Patent EA-029149-B1 (EA)
Title: Pharmaceutical compositions comprising ceftaroline fosamil for treating bacterial infections
Inventor: THYE DIRK
IPC: A61K31/545
Filed: 2010-09-21
Abstract: The present invention relates to pharmaceutical compositions comprising ceftaroline fosamil for treating bacterial infections, such as complicated skin and structure infections (cSSSI) and community-acquired bacterial pneumonia (CABP), wherein the composition comprises about 200 to about 800 mg of ceftaroline fosamil and L-arginine and less than 2% of an L-arginine adduct.
Patent EA-025058-B1 (EA)
Title: Oral veterinary composition, use thereof in treatment and method of treatment by administration thereof
Inventor: DRAGET KURT INGAR
IPC: A61K31/496
Filed: 2011-04-11
Abstract: This invention provides an oral composition comprising a physiologically tolerable gelled oil-in-water emulsion, an attractant which is a chicken, beef, pork, lamb, rabbit or fish flavouring, and a veterinary drug, wherein the water phase of the gelled oil-in-water emulsion contains a physiologically tolerable gelling agent selected from gelatin, alginate, carrageenan and pectin. Also provided are the use of said composition in treatment of a non-human mammalian subject and a method of treatment thereof by oral administration of said composition.
Patent EA-022727-B1 (EA)
Title: Process for removing nitrous oxide from a gas stream
Inventor: ANGELIDES CHRISTOS ODYSSEA
IPC: B01D53/86
Filed: 2011-05-17
Abstract: A process is disclosed for the removal of nitrous oxide from a gas stream having a contaminating concentration of nitrous oxide to provide a gas stream with a significantly reduced concentration of nitrous oxide. The process includes passing the feed gas stream through a first heat transfer zone that is in heat exchange relationship with a product stream whereby heat is transferred from the product stream to the feed gas stream to thereby provide a heated gas stream; passing said heated gas stream to a reaction zone containing an NO decomposition catalyst and optionally a combination of other catalyst that provides for the decomposition of nitrous oxide or other contaminants and yielding therefrom a product stream having a reduced concentration of nitrous oxide; and passing the product stream to the first heat transfer zone to provide a cooled product stream.
Patent EA-023575-B1 (EA)
Title: Method for producing agglomerates having rubber and wax, agglomerates produced according to the method, and use thereof in asphalts or bitumen masses
Inventor: BUTZ THORSTEN
IPC: E01C5/00
Filed: 2011-07-10
Abstract: The invention relates to a method for producing a bulk material of agglomerates, wherein a composition of the agglomerate is made of rubber particles and wax, and to the use of said bulk material to produce asphalt or bitumen masses, wherein rubber is activated by swelling and using a swelling agent and a melt made of viscosity-reducing wax and of optional polyoctenamer is added, wherein the activated rubber particles are agglomerated by means of the viscosity-reducing wax and optional adhesion-improving substances, wherein the resulting larger volume leads to a viscosity reduction and the softening leads to a more intimate and more homogeneous wetting with the wax and, in the mixed good to be produced, a viscosity reduction remaining stable in the mixed good for <180 min and an increased stability of the cross-linking of the rubber molecules among each other after the agglomerates have been incorporated are achieved.
Patent EA-024026-B1 (EA)
Title: Novel salts and polymorphic forms of afatinib
Inventor: GIDWANI RAMESH MATIORAM
IPC: C07D405/12
Filed: 2011-11-23
Abstract: Afatinib salts and crystalline forms thereof are described in the present application and processes for their preparation. Crystalline forms of Afatinib are also described in the present application and processes for their preparation. The present invention also includes pharmaceutical compositions of such Afatinib salts and crystalline forms thereof or crystalline forms of Afatinib, methods of their preparation and the use thereof in the treatment of a patient in need thereof.
Patent EA-032678-B1 (EA)
Title: Nanoparticle smart tags for use in subterranean formations
Inventor: SARKAR DIPTABHAS
IPC: C09K8/62
Filed: 2012-09-21
Abstract: The present invention relates to nanoparticle smart tags and the use of nanoparticle smart tags in the detection of analyte. In particular, the present invention relates to nanoparticle smart tags that may be used in subgeologic formations to detect analytes of interest in real-time. One embodiment of the present invention provides a suspension having a nanoparticle smart tag analyte complex formed by an interaction having a nanoparticle smart tag and an analyte; and a subterranean treatment fluid.
Patent EA-029645-B1 (EA)
Title: Design method for three-dimensional curved airfoil section
Inventor: CHEN YUQI
Filed: 2013-04-10
Abstract: Disclosed is a design method for a three-dimensional curved airfoil section. The method comprises the following steps: collecting arc coordinate data of a conventional 2D airfoil section such as (x, y) and (x, y); according to the conventional airfoil section coordinate data, calculating an increment between x coordinate points of a chord; determining a radius of rotation R of the airfoil section to be arranged according to the design; creating a three-dimensional airfoil section arc coordinate (x, y, z), wherein yis a coordinate value of the thickness of the 2D airfoil section; and by this analogy, calculating a three-dimensional airfoil section arc coordinate cluster (x, y, z), etc. This method improves the aerodynamic profile of a blade by means of optimising a three-dimensional curved airfoil section, thereby increasing aerodynamic force efficiency of a rotary blade on the basis of the same materials and structural arrangement.
Patent EA-032006-B1 (EA)
Inventor: ANTLE VINCENT D
IPC: C08B37/16
Filed: 2013-10-21
Abstract: Изобретение относится к композициям алкилированного циклодекстрина с низким содержанием хлорида, а также способам их получения и применения. Способы согласно настоящему изобретению обеспечивают алкилированные циклодекстрины с низким содержанием агентов, разлагающих лекарственное средство, и хлорида.
Patent EA-028441-B1 (EA)
Title: Method and device for bending sheets of glass by running them on a bed of rolls
Inventor: THUILLIER SEBASTIEN
IPC: C03B35/18
Filed: 2013-10-02
Abstract: The invention relates to a device for bending sheets of glass running between a bed of upper rolls and a bed of lower rolls forming a shaping bed that pinches the sheets as they run, said shaping bed being disposed in a path having a curved profile in the running direction of the sheets of glass, said shaping bed comprising at least one roll of what is known as the rod/sheath type comprising a fixed metal rod preformed in a curved profile lengthwise and a flexible sheath that is able to rotate about said rod, said sheath being rotated about said rod. The roll of the rod/sheath type may comprise a metal rod preformed in a curved profile lengthwise and a flexible sheath that is able to rotate about the rod, said sheath comprising a first envelope made of a polymer material and a second envelope made of a flexible metal material disposed around the first envelope, the first and the second envelope rotating together as one.
Patent EA-035512-B1 (EA)
Title: Promoters suitable for heterologous gene expression in yeast
Inventor: MC GRATH JESSICA LEIGH
IPC: C12N15/81
Filed: 2015-01-29
Abstract: The present invention relates to the use of novel promoters for heterologous gene expression, preferably for expression of genes in organisms of the genus Yarrowia, to the genetically modified organisms of the genus Yarrowia, and to a process for producing biosynthetic products by cultivating the genetically modified organisms.
Patent EA-034080-B1 (EA)
Title: Electric connecting element for contacting an electrically conductive structure on a substrate
Inventor: SCHMALBUCH KLAUS
IPC: H05B3/84
Filed: 2015-03-11
Abstract: The present invention relates to an electric connecting element (1) for electrically contacting an electrically conductive structure (5) on a substrate (6), at least comprising two solid sub-elements (2, 3) made from different material, wherein the first sub-element (2) is provided in order to be soldered to the electrically conductive structure (5) and the second sub-element (3) is provided in order to be connected to an electric connection cable, wherein the first sub-element (2) and the second sub-element (3) are interconnected by means of at least one rivet (4).