baber/WOPTO huggingface dataset:
Patent HK-1078080-A1 (HK)
Title: Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
Inventor: HAYASHI YOSHIO
IPC: C07D409/14
Filed: 2005-11-11
Abstract: Compounds represented by the following structure (I) are disclosed: as are methods for making such compounds, wherein said methods comprise reacting a diacyldiketopiperazine with a first aldehyde to produce an intermediate compound; and reacting the intermediate compound with a second aldehyde to produce the class of compounds with the generic structure, where the first aldehyde and the second aldehydes are selected from the group consisting of an oxazolecarboxaldehyde, imidazolecarboxaldehyde, a benzaldehyde, imidazolecarboxaldehyde derivatives, and benzaldehyde derivatives, thereby forming the above compound wherein R<SUB>1</SUB>, R<SUB>1</SUB>', R<SUB>1</SUB>'', R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB>, and R<SUB>6</SUB>, X<SUB>1 </SUB>and X<SUB>2</SUB>, Y, Z, Z<SUB>1</SUB>, Z<SUB>2</SUB>, Z<SUB>3</SUB>, and Z<SUB>4 </SUB>may each be separately defined in a manner consistent with the accompanying description. Compositions and methods for treating cancer and fungal infection are also disclosed.
Patent HK-1083511-A1 (HK)
Title: Antibacterial amide macrocycles
Inventor: LAMPE THOMAS
IPC: A61K38/00
Filed: 2006-03-22
Abstract: The invention relates to antibacterial amide macrocycles, to methods for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of illness, especially bacterial infections.
Patent HK-1092353-A1 (HK)
Title: Thiazoles and oxazoles useful as modulators of atp-binding cassette transporters
Inventor: HADIDA RUAH SARAH
IPC: C07D417/04
Filed: 2006-08-24
Abstract: The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Patent HK-1097855-A1 (HK)
Title: Method of detecting probnp with a monoclonal antibody binding to the amino acid 41-46
Inventor: KLEMT VOLKER
IPC: A61K39/00
Filed: 2007-02-28
Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
Patent HK-1100175-A1 (HK)
Title: substituted oxindol derivatives and medicaments containing the same
Inventor: LUBISCH WILFRIED
IPC: A61K/
Filed: 2007-05-29
Abstract: 1-sulfonyl-2-oxo-2,3-dihydroindole derivatives (I) and their tautomers, enantiomers and/or diastereomers, prodrugs and salts are new. 1-sulfonyl-2-oxo-2,3-dihydroindole derivatives of formula (I) and their tautomers, enantiomers and/or diastereomers, prodrugs and salts are new. A : 6-10C aryl (optionally substituted); B : (partially) aromatic 6-10C mono- or bi-cyclic residue (optionally substituted); R 1>H, 1-6C alkyl, OH, 1-4C alkoxy, di(1-4C alkyl)amino, CN, carbamoyl, trifluoromethoxy, trifluoromethyl, bromo, fluoro, chloro, iodo, nitro, formamido, 1-4C alkylcarbonylamino or ureido; R 2>H, 1-4C alkyl, 1-4C alkoxy, chloro or fluoro; R 3>W-X-Y-Z; W : 1-4C alkylene, (0-4C alkylene)-O-(0-4C alkylene) or (0-4C alkylene)-NR 15>-(0-4C alkylene); R 15>H or 1-4C alkyl; X : CO, SO 2, C=NH or C=N-CN; Y : e.g. pyrrolidindiyl, piperazindiyl or piperidindiyl (optionally substituted); and Z : e.g. pyrrolidinyl, azepinyl or morpholino. The full definitions are given in the DEFINITIONS (Full Definitions) field. An independent claim is also included for two methods for preparing (I). [Image] ACTIVITY : Uropathic; Antithrombotic; Anticoagulant; Hypotensive; Cardiant; Antianginal; Antiischemic; Nephrotropic; Antiinflammatory; Antidiuretic; Hepatotropic; Antiulcer; Antiemetic; Antidepressant; Tranquilizer; Nootropic; Neuroprotective. MECHANISM OF ACTION : Vasopressin receptor antagonist, e.g. V 1a and V 1b receptor antagonist. N-(1-(2,4-dimethoxybenzenesulfonyl-5-chloro-2-oxo-3-(2-methoxyphenyl)-2,3-dihydro-1H-indol-3-yl) 4-(1-methylpiperidin-4-yl)-piperazine-1-carboxamide dihydrochloride (Ia) had affinity constant for the V 1a receptor below 100 nM, when tested by the method of Br. J. Pharmacol., 125 (1998) 1463.
Patent HK-1125226-A1 (HK)
Title: Packaging method of electric component
Inventor: MATSUMURA TAKASHI
IPC: H05K3/32
Filed: 2009-03-30
Abstract: A mounting method and a mounting device are provided, which can mount an electric component with high reliability by using an adhesive.  The present invention is a mounting method including the step of thermocompression bonding an IC chip 20 onto a wiring board 10 by using an anisotropic conductive adhesive film 7. During the thermocompression bonding, a top region of the IC chip 20 is pressed against the wiring board 10 with a predetermined pressure, and a side region of the IC chip 20 is pressed with a pressure smaller than the pressure applied to the top region of the IC chip 20. An elastomer having rubber hardness of 40 or more and 80 or less is used for a compression bonding portion 6 of a thermocompression bonding head 4. The anisotropic conductive adhesive film 7 contains a binding resin 7b having melting viscosity of 1.0 x 10 2  mPa · s or more and 1.0 x 10 5  mPa·s or less.
Patent HK-1208376-A1 (HK)
Title: Artificial antigen presenting cell for preparing cd8 cell suspension for use in the treatment of cancer cd8
Inventor: DEGRAW JULI
IPC: C12N5/0783
Filed: 2015-09-18
Abstract: T cell responses are often diminished in humans with a compromised immune system. We have developed a method to isolate, stimulate and expand naïve cytotoxic T lymphocyte precursors (CTLp) to antigen-specific effectors, capable of lysing tumor cells in vivo. This ex vivo protocol produces fully functional effectors. Artificial antigen presenting cells (AAPCs; e.g. from Drosophila melanogaster) transfected with multiple human HLA class I cancer antigens and defined accessory molecules, are used to stimulate CD8+ T cells from both normal donors and cancer patients. The class I molecules expressed to a high density on the surface of the Drosophila cells are empty, allowing for efficient loading of multiple peptides that results in the generation of polyclonal responses recognizing tumor cells endogenously expressing the specific peptides. The responses generated are robust, antigen-specific and reproducible if the peptide epitope is a defined immunogen. This artificial antigen expression system can be adapted to treat most cancers in a significant majority of the population.
Patent HK-1000785-A1 (HK)
Title: Oxygen-containing heterocyclic compounds
Inventor: KAWAKITA TAKASHI
IPC: C07D307/79
Filed: 1997-11-28
Abstract: An oxygen-containing heterocyclic compound represented by following Formula (I): <CHEM> wherein R<1> and R<2> independently represent hydrogen, lower alkyl, cyano, -(CH2)n-E-CO-F (wherein E represents a bond, O, or NH; F represents OR<6> or NR<7>R<8>; and n represents an integer of 0 to 4), or the like; R<1> and R<2> are combined to represent a saturated carbon ring together with a carbon atom adjacent thereto; or R<2>, and R<11> or R<13> described below are combined to form a single bond; R<3> represents hydrogen, phenyl, or halogen; R<4> represents hydroxy, lower alkoxy, or the like; A represents -C(R<9>)(R<10>)- or O; B represents O, NR<11>, -C(R<12>)(R<13>)-, or -C(R<14>)(R<15>)-C(R<16>)(R<17>)-; D represents (i) -C(R<18>)(R<19>)-X- (wherein X represents -C(R<21>)(R<22>)-, S, or NR<23>), (ii) -C(R<19a>)=Y- ÄY represents -C(R<24>)-Z- (wherein Z represents CONH, CONHCH2, or a bond), or NÜ, or (iii) a bond; and R<5> represents aryl, an aromatic heterocyclic group, cycloalkyl, pyridine-N-oxide, cyano, or lower alkoxycarbonyl; or a pharmaceutically acceptable salt thereof.
Patent HK-1003000-A1 (HK)
Title: Spiro compounds
Inventor: HAYAKAWA ISAO
IPC: C07D221/20
Filed: 1998-03-12
Abstract: A spiro compound of formula I: <CHEM> wherein a represents an integer equal to 0 or 1; b represents an integer equal to 2 through 5, inclusive; c represents an integer equal to 0 or 1; and d represents an integer equal to 0 through 2, inclusive; Z represents >CHR<1>, >NR<2>, >C=NOR<3>, an oxygen atom or a sulfur atom.
Patent HK-1011307-A1 (HK)
Title: Electrostatic spraying device
Inventor: JEFFERIES ANDREW
IPC: B05B5/16
Filed: 1998-11-27
Abstract: An electrostatic spraying device is provided with a container (16) for the liquid to be sprayed and a capillary structure (22) extending into the container. To maintain a substantially constant liquid level at the location where liquid is drawn into the capillary structure, the container is partitioned into two chambers one (68) of which is isolated from atmosphere and the other (66) of which is in communication with atmosphere. The capillary structure (22) extends through one chamber and the arrangement is such that the liquid level at the location where the capillary structure communicates with the liquid is maintained substantially constant over a wide range of variation of the liquid level within the other chamber. The upper end of the capillary structure may be provided with an oblique end face (50; 70, 72) to facilitate dispersal of the spray into the surroundings. <IMAGE>
Patent HK-1014197-A1 (HK)
Title: Automotive lubricant
Inventor: OSTYN MARCEL ALPHONSE JOSEPH
IPC: C10N10/04
Filed: 1998-12-24
Abstract: An automotive lubricant comprising a white oil basestock and one or more additives, at least one additive being an antioxidant. The white oil basestock may be blended with mineral oil and/or synthetic oil basestocks. The lubricant can be used, for example, as an engine oil, gear oil or automatic transmission fluid.
Patent IE-20020681-A1 (IE)
Title: DNA sequence imparting cytoplasmic male sterility, mitochondrial genome, nuclear genome, mitochondria and plant containing said sequence and process for the preparation of hybrids
Inventor: BUDAR FRANCOISE
IPC: C12Q1/68
Filed: 1991-09-20
Abstract: The present invention relates to a plant belonging to the genus Brassica possessing a genome which confers cytoplasmic male sterility on the said plant. It also relates to a method for preparing hybrid plants using such a plant, as well as a hybrid thus obtained.
Patent IE-20050093-A1 (IE)
Title: Mattress
Inventor: DALY PATRICK NOEL
IPC: A47C27/14
Filed: 2005-02-21
Abstract: A mattress construction comprises a base support layer, an outer covering supported if necessary by a suitable framework, and optional lining material placed above the base support layer and removably attached to the outer covering, at least one inflatable support structure on which a user of the mattress lies and a removable cover attached to the outer covering above the inflatable support structure. The inflatable support structure comprises an air impermeable envelope enclosing a body of foam material and preferably also includes a valve to regulate the air pressure within the envelope.
Patent IE-20050565-A1 (IE)
Title: Warewashing system
Inventor: MITCHEM DAVID ROY
IPC: A47L15/42
Filed: 2005-08-26
Abstract: A warewashing machine (1) has a water tank (9) connected to a water inlet (13). A water level switch (17) is adapted to operate when a water level within the tank means is below a predetermined level at which sufficient water is present to carry out a predetermined cycle of operation of the machine such as a rinse cycle. <Figure 2>
Patent IE-20060460-A1 (IE)
Title: Power management of multiple processors
Inventor: MUNGER WILLIAM C
IPC: G06F1/26
Filed: 2006-06-16
Abstract: An information handling system having a plurality of physical processors capable of operating in either a low power or a high power state, and capable of running logical processors that may execute program threads.  Each program thread is assigned to be executed in a respective logical processor.  The assignment of each program thread to the respective logical processor is determined by whether the program thread requires high-utilization or low-utilization of the plurality of physical processors in the information handling system.  To conserve power in the information handling system, high-utilization program threads are assigned to be executed in logical processors running in as few physical processors operating in the high power state, and low-utilization program threads are assigned to physical processors operating in the low power state.  To maximize execution speed of program threads in the information handling system, high-utilization program threads are assigned to be executed in logical processors running in different physical processors operating in the high power state, and low-utilization program threads are assigned to any physical processor.
Patent IT-MI931007-A1 (IT)
Inventor: ABUSLEME JULIO A
IPC: C08F/
Filed: 1993-05-18
Abstract: In a process of (co)polymerization in aqueous emulsion of fluorinated olefinic monomers it is added to the reaction medium a microemulsion of fluoropolyoxyalkylenes having hydrogenated end groups and/or hydrogenated repetitive units. A remarkable reduction in the reaction induction period is so obtained, with formation of a product with improved mechanical properties and higher thermal and chemical resistance.
Patent IT-MI940305-A1 (IT)
Inventor: GOVONI GABRIELE
IPC: C08F10/00
Filed: 1994-02-21
Abstract: PCT No. PCT/EP95/00544 Sec. 371 Date Dec. 8, 1995 Sec. 102(e) Date Dec. 8, 1995 PCT Filed Feb. 15, 1995 PCT Pub. No. WO95/22565 PCT Pub. Date Aug. 24, 1995A process for polymerizing olefins using a fluidized bed, in which the monomer entry point is located at a point above the bed height. A pre-polymerization step can be conducted using a Z/N catalyst along with an alkane diluent, and resultant liquid phase is introduced into the fluidized bed above the bed height. The process may use several reactors in series arrangement.
Patent IT-MI942442-A1 (IT)
Title: Procedimento e disposizione di misurazione atti a determinare il livello, la torbidita'ed un'eventuale quantita' di schiuma della
Inventor: WENTZLAFF GUNTER
IPC: D06F34/08
Filed: 1994-12-01
Abstract: Procedimento e disposizione di misurazione atti a determinare il livello, la torbidità ed un'eventuale quantità di schiuma della liscivia in una macchina lavatrice o lavastoviglie a comando automatico.Per mezzo della disposizione di misurazione uno o più fasci di raggi ottici vengono diretti sulla superficie fittizia della liscivia con rispettivamente un angolo di incidenza di 0° 90°. Le riflessioni vengono determinate per mezzo di uno schermo ricevitore della disposizione di misurazione per quanto concerne la loro tipologia di trasmissione e/oppure di ricezione, la loro diffusione e la loro attenuazione.Per effetto del procedimento di cui all'invenzione il livello, la torbidità ed un'eventuale quantità di schiuma della liscivia in una macchina lavatrice o lavastoviglie vengono determinati per mezzo di un unico sistema di misurazione.(Figura 2).
Patent IT-MI951808-A1 (IT)
Title: Macchina per maglieria in particolare macchina rettilinea per maglieria con aghi a pistone
Inventor: SCHNAIDT GERLINDE
IPC: D04B15/20
Filed: 1995-08-25
Abstract: Nel caso di una macchina per maglieria, in particolare macchina rettilinea per maglieria, con aghi a pistone mobili singolarmente in scanalature dell'ago di un letto degli aghi con un corpo dell'ago, con un uncino dell'ago e con un piede dell'ago, nonché con un pistone con un piede del pistone e con lamelle del pistone nel corpo dell'ago, che vengono allargate all'atto dell'avanzamento attraverso l'uncino dell'ago per immergere un ago prensile, in considerazione della fabbricazione di articoli a maglia con divisioni fini è previsto che le lamelle (1, 2) del pistone siano guidate nel corpo (3) dell'ago e il pistone sia guidato nella scanalatura (4) dell'ago del letto degli aghi.
Patent IT-MI951944-A1 (IT)
Title: Bastoncino di inchiostro solido
Inventor: JONES BRENT R
IPC: B41J2/175
Filed: 1995-09-19
Abstract: Si descrive una forma di bastoncino di inchiostro da usare in una tramoggia di alimentazione di bastoncini di inchiostro di una stampante, in cui i lati opposti del bastoncino di inchiostro sono rastremati o inclinati rispetto ad una linea orizzontale in modo che almeno una zona tra la sommità e il fondo del bastoncino di inchiostro sia ad una distanza dalla linea orizzontale maggiore di quella del punto di unione delle pareti laterali e il fondo del bastoncino di inchiostro. La sagoma o geometria del bastoncino di inchiostro può essere collegata ad un particolare colore.
Patent IT-MI952452-A1 (IT)
Title: Processo per produrre polveri nanometriche di ossidi metallici da cloruri metallici
Inventor: CASALE MARIACRISTINA
IPC: C01G23/07
Filed: 1995-11-24
Abstract: Vapori di cloruri metallici sono miscelati a vapori di un alcool e trascinati in una camera di reazione sotto l'azione di un raggio laser per formare i corrispondenti alcossidi e pirolizzare, così producendosi polveri le cui particelle sono ben cristallizzate ed hanno diametro compreso fra 5 nm e 20 nm.(Fig. 1/B).
Patent IT-MN910001-A1 (IT)
Title: Forno a gas adatto per cuocere pane prodotti di pasticceria e  particolarmente pizze mediante irraggiamento e conduzione
Inventor: MODENA LUIGI
Filed: 1991-01-24
Abstract: IL FORNO A GAS, ADATTO PER CUOCERE PANE, PRODOTTI DI PASTICCERIA E PARTICOLARMENTE PIZZE, MEDIANTE IRRAGGIAMENTO E CONDUZIONE, è costituito da un forno all'interno del quale il calore è trasmesso dal basso, mediante conduzione dalla platea in pietra refrattaria e dall'alto per irraggiamento, mediante i raggi infrarossi emessi dalla combustione del gas sulla superficie delle piastre di porcellana porosa. I fumi prodotti dalla combustione non vengono a contatto con i prodotti da cuocere.
Patent IT-NA930007-A1 (IT)
Title: Protesi esterna per incontinenza urinaria maschile
Inventor: COSTAGLIOLA BRUNO
Filed: 1993-03-31
Abstract: Questa protesi nasce per risolvere il problema dell'incontinenza urinaria maschile, in alternativa a vari sistemi (pannolini, pannolini mutandine, profilattico modificato alla sua estremità per consentire l'attacco di una busta delle urine, etc.). Esso sfrutta un sistema a diaframma, costituito da una membrana (I) di materiale lattice sottile, con un foro al centro di dimensione tale da consentire l'introduzione dell'asta maschile e mantenere un giusta tenuta, senza però costringerla; osservando le due figure nel riquadro sottostante si potrà capire facilmente il principio che viene sfruttato e mentre una è formata da una membrana (I), ghiera (2), cilindro (3), valvola unidirezionale (4), busta di raccolta (5), e tappo di scarico (6), e può essere contenuta nello slip ed il peso della busta piena potrà essere sorretto anche dai pantaloni, e per lo scarico basterà aprire il tappo di scarico e svuotare la busta in un comune water senza rimuovere la protesi; l'altro sistema è più semplice e funziona come catetere esterno, e si collega ad una busta normale delle urine, come nella figura.
Patent IT-RM950129-A1 (IT)
Title: Dispositivo tridimensionale di movimentazione piezoelettrica per  microscopia.
Inventor: CRICENTI ANTONIO
IPC: G02B/
Filed: 1995-03-03
Abstract: Dispositivo tridimensionale di movimentazione piezoelettrica per microscopia, particolarmente idoneo per essere inserito oppure aggiunto ad un sistema di microscopia (microscopio), costituito da due cilindri piezoelettrici (1) e (2) sui quali è montata una base magnetica (4) sulla quale viene posizionato il porta campione (6) che supporta il campione (7). Essosi colloca nel campo dell'ottica e più in particolare in quello della fabbricazione di microscopi o parti di essi. Il suo campo applicativo riguarda l'analisi di nuovi materiali a semiconduttori, sensori clinici, ottici da utilizzare nel campo biologico, bioingengneristico, per la visualizzazione di virus, stima di cellule anche e soprattutto tumorali, ecc.
Patent IT-RM950192-A1 (IT)
Title: Procedimento per il controllo della velocita' di rotazione di un compressore di un frigorifero.
Inventor: LEE KUN BIN
IPC: F25D11/02
Filed: 1995-03-28
Abstract: La presente invenzione consente di controllare differenti velocità di rotazione di un compressore che comprende un motore senza spazzole, secondo il valore della frequenza utilizzato in un frigorifero. Nel presente procedimento di controllo, quando il numero totale NO di volte che è stato aperto lo scomparto F oppure lo scomparto R, oppure l'intervallo di tempo complessivo tO di apertura dell'uno o dell'altro di detti scomparti, in un determinato intervallo di tempo, superano i valori rispettivi di riferimento, allora la velocità di rotazione del compressore viene aumentata di un valore prefissato. D'altra parte, quando l'intervallo di tempo ininterrotto di chiusura della porta, supera un determinato valore di riferimento, allora la velocità di rotazione del compressore viene diminuita di un valore prefissato.(FIG. 2).
Patent IT-RM950594-A1 (IT)
Title: Apparato elettronico per recepire ostacoli ad uso dei non vedenti
Inventor: CARDAROLA ALESSANDRO
IPC: A61F/
Filed: 1995-09-04
Abstract: Occhiale per non vedenti ad emissione di raggi infrarossi e la ricezione di questi riflessa da eventuali oggetti, il tutto a mezzo di diverse amplificazioni per rilevare le distanze. Nell'occhiale è inserito anche un rivelatore di colori.A corredo un emettitore e ricevitore posto in una scarpa rivelerà oggetti minuti nella deambulazione.
Patent IT-UD930053-A1 (IT)
Inventor: COLOMBI LUIGI
IPC: B32B37/00
Filed: 1993-03-31
Abstract: Device to apply in line a plastic coating to both sides of a support, the device being suitable to apply plastic films (11-111) continuously to supports (12) of a paper type, to woven fabrics, to metal sheets, etc. for the purposes of protection, reinforcement and/or surface finish, the support (12) being continuous or consisting of sheets and being fed along a plane (15) of application of the plastic coating, the device comprising calenders (16) which consist of at least one first heated chromium-plated steel roll (17) polished to a mirror finish and a second unheated rubberised roll (18) of a smaller diameter, the device comprising two substantially equal calenders (16a-16b) positioned in succession on the common and substantially horizontal plane (15) of application of the plastic coating to the support (12), the calenders (16a-16b) being arranged reciprocally rotated substantially by 180 DEG  in relation to the common plane (15) of application of the plastic coating, so that the respective surface of the support (12) affected by application of the plastic film (11-111) cooperates with the respective chromium-plated steel roll (17) polished to a mirror finish. <IMAGE>
Patent IT-VI950198-A1 (IT)
Title: Congegno meccanico applicabile ai trattori agricoli  per fresare  il terreno lungo i filari delle coltivazioni
Inventor: BEDIN ANGELO
IPC: A01B/
Filed: 1995-12-12
Abstract: Si tratta di un congegno meccanico applicabile ai trattori agricoli, per fresare il terreno lungo i filari delle coltivazioni in genere.- Il congegno in oggetto può essere mosso meccanicamente od idraulicamente e la sua posizione in altezza ed inclinazione rispetto all'orizzontale può essere scelta ed adattata dallo stesso operatore che guida il trattore durante la lavorazione del terreno.-L'albero dell'elemento fresante è sopportato ad entrambe le sue estremità ed il congegno può liberamente oscillare incontrando qualche ostacolo accidentale di qualsiasi genere.-