baber/WOPTO huggingface dataset:
Patent AU-2019397384-A1 (AU)
Title: Pneumatic valve/pressure vessel plastic metal composite cover with bayonet retention feature
Inventor: MULAKALA CHANDRA SEKHAR
IPC: F16B5/10
Filed: 2019-11-27
Abstract: A fastener-less valve cover plate assembly (20) that can be used to enclose a pressure chamber, such as a valve chamber of a relay valve. Installation of the components of the fastener-less valve cover plate assembly is simplified as compared to prior art cover plates utilizing fasteners, while still providing suitable performance. In addition, the fastener-less valve cover plate assembly is not readily disassembled with common tools thereby discouraging tampering.
Patent AU-2019403245-A1 (AU)
Title: Antibodies that neutralize hepatitis B virus and uses thereof
Inventor: CORTI DAVIDE
IPC: A61P31/20
Filed: 2019-12-18
Abstract: The present disclosure relates to antibodies, and antigen binding fragments thereof, that can bind to the antigenic loop region of hepatitis B surface antigen (HBsAg) and can neutralize infection of both hepatitis B virus (HBV) and hepatitis delta virus (HDV). The present disclosure also relates to epitopes to which the antibodies and antigen binding fragments bind, as well as to fusion proteins that comprise the antigen binding fragments, and to nucleic acids that encode and cells that produce such antibodies and antibody fragments. In addition, the present disclosure relates to the use of the antibodies and antibody fragments of the present disclosure in the diagnosis, prophylaxis and treatment of hepatitis B and hepatitis D.
Patent AU-2019440118-A1 (AU)
Title: Process for producing silicon metal-containing agglomerates
Inventor: RIMBÖCK KARL-HEINZ
IPC: C01B33/02
Filed: 2019-04-03
Abstract: The present invention provides a process for producing silicon metal-containing agglomerates which comprises agglomerating a mixture of finely divided silicon metal-containing particles having a particle size parameter dso of at most 250 pm and in the dry state a silicon metal content of at least 10% by mass, binder containing 90% to 98% by mass of silicon dioxide and having a specific surface area of 15 to 35 m
Patent AU-2019455073-A1 (AU)
Title: Image encoding method, image decoding method, encoder, decoder and storage medium
Inventor: WAN SHUAI
IPC: H04N19/117
Filed: 2019-06-25
Abstract: Disclosed are an image encoding method, an image decoding method, an encoder, a decoder, and a storage medium. Before encoding in accordance with MIP modes, an encoder uniformly modifies initial right shift parameters corresponding to different sizes and different MIP mode numbers according to offset parameters, wherein the offset parameters are used for indicating the right shift digits of predicted values; and during encoding in accordance with the MIP modes, performs encoding in accordance with the offset parameters. Before decoding in accordance with MIP modes, a decoder uniformly modifies initial right shift parameters corresponding to different sizes and different MIP mode numbers according to offset parameters, wherein the offset parameters are used for indicating the right shift digits of predicted values; and during decoding in accordance with the MIP modes, performs decoding in accordance with the offset parameters.
Patent AU-2020200400-A1 (AU)
Title: Oral care implement and filament therefor
Inventor: HOHLBEIN DOUGLAS J
IPC: A46B9/04
Filed: 2020-01-21
Abstract: An oral care implement (100) that includes a handle and a head (120). Cleaning elements (130) are coupled to the head and extend from the front surface (121) of the head. At least one of the cleaning elements is a first type of cleaning element that extends from a first end to a second end along a longitudinal axis and has a polygonal transverse cross-sectional shape. The first type of cleaning element has an outer surface having a plurality of elongated faces and a plurality of elongated edges. The first type of cleaning element is formed from a first component and a second component, the first and second components being different in at least one characteristic. An interface of the first and second components is located along at least one of the elongated edges. Figure 2 /-122
Patent AU-2020204451-A1 (AU)
Title: Lakes Based Seawater Vapour System - A permanent solution to fix Australian drought and wildfires
Inventor: HALES ZAN
IPC: A01G15/00
Filed: 2020-07-02
Abstract: A system for pumping seawater from the ocean into a number of selected locations in Australia to 
form a network of inter-supportive shallow saltwater lakes, to provide a base for continuous water 
evaporation. This evaporation will increase the chance of condensation, and thereby convert 
seawater to rain. A number of natural basins will be filled with water pumped from the ocean, which 
is ducted from the pump facilities via pipelines. The selection of locations for lakes is based on 
considerations including size, depth, temperature, and geophysical structure of the basins.
Patent AU-2020215684-A1 (AU)
Title: 2h-indazole derivatives as therapeutic agents for brain cancers and brain metastases
Inventor: GRECO MICHAEL NICHOLAS
IPC: C07D401/14
Filed: 2020-01-28
Abstract: Methods are disclosed for treating brain cancers or brain metastases from other cancers, or prevention of brain metastases, associated with CDK4 and/or CDK6 activities, where the methods comprise administering to a subject in need thereof a therapeutically effective amount of a compound of formula (I). Use of a compound of formula (I) for the manufacture of a medicament for treatment of brain cancer or brain metastases from other cancers, or prevention of brain metastases, associated with CDK4 and/or CDK6 activity is also disclosed.
Patent AU-2020234063-A1 (AU)
Title: Polypeptide with enhanced rate of spontaneous isopeptide bond formation with its peptide tag partner and uses thereof
Inventor: HOWARTH MARK
IPC: C12N15/85
Filed: 2020-03-13
Abstract: The present invention relates to a polypeptide that forms one part of a two- part linker in which the polypeptide spontaneously forms an isopeptide bond with a peptide tag, the second part of the two-part linker. Nucleic acid molecules encoding the polypeptide, vectors comprising said nucleic acid molecules,and host cells comprising said vectors and nucleic acid molecules are also provided. A kit comprising said two-part linker (i.e. peptide tag and polypeptide binding partner), and/or nucleic acid molecules/vectors is also provided. A method of producing the polypeptide (binding partner) and the uses of the polypeptide of the invention are also provided.
Patent AU-2020238002-A1 (AU)
Title: Macrocyclic compounds
Inventor: ZHANG JUNHU
IPC: A61P35/00
Filed: 2020-03-06
Abstract: Disclosed are macrocyclic compounds of formula (I) comprising a 2-carboxy indole ring. Such compounds, and their pharmaceutically acceptable salts, are useful as Mcl-1 (myeloid cell leukemia-1) inhibitors. The compounds may be used in treating a disease or condition, such as cancer.
Patent AU-2020239759-A1 (AU)
Title: User interfaces for enabling an activity
Inventor: ZHANG YONGJUN
IPC: G06F3/048
Filed: 2020-09-24
Abstract: The present disclosure generally relates to user interfaces for enabling an activity using a 
computer system. In some embodiments, exemplary user interfaces for invoking an activity 
associated with an application are described. In some embodiments, exemplary user interfaces 
for customizing displayed content based on circumstances under which the content was invoked 
are described. In some embodiments, exemplary user interfaces for managing applications that 
were used to enable activities are described. In some embodiments, exemplary user interfaces 
for managing settings for applications used to enable activities are described.
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Patent AU-2020252069-A1 (AU)
Title: Vector co-expressing truncated von Willebrand Factor and Factor VIII
Inventor: LI QI
IPC: C07K14/755
Filed: 2020-03-27
Abstract: The present invention relates to a co-expression vector that comprises both truncated von Williebrand Factor (vWF)-Fc DNA construct and B-domain deleted FVIII DNA construct in the same vector. By co-expressing FVIII and truncated vWF-Fc with one expression vector in cells, the present invention controls the ratio of gene templates for FVIII and vWF proteins, provides a higher protein ratio of FVIII to vWF during cell expression, that results in a better occupancy of FVIII in vWF, and creates a higher yield (>1000 IU/ml) and more stable expression of FVIII protein molecules. In one preferred embodiment, the truncated vWF contains mutations of cysteines in the D'D3 domain of vWF to reduce multimer assembly of recombinant vWF during expression, and thus increasing recovery and quality of FVIII.
Patent AU-2020253391-A1 (AU)
Title: Compositions containing brazzein
Inventor: PRAKASH INDRA
IPC: A23L2/60
Filed: 2020-04-01
Abstract: Compositions comprising brazzein (or analogs thereof), including sweetener compositions, flavor modifying compositions, sweetened compositions, flavor modified compositions are disclosed. Also disclosed are methods of improving the temporal profile, flavor profile and/or taste profile of sweetenable compositions, such as beverages.
Patent AU-2020263470-A1 (AU)
Title: Refuse collection vehicle positioning
Inventor: WILLIAMS ROBERT B
IPC: B65F3/02
Filed: 2020-04-23
Abstract: A refuse collection vehicle includes a fork assembly that is operable to engage one or more fork pockets of a refuse container, a lift arm that is operable to lift a refuse container, and at least one sensor that is configured to collect data indicating a position of the one or more fork pockets of the refuse container. A position of at least one of the fork assembly or the lift arm is adjusted in response to the data collected by the at least one sensor.
Patent AU-2020266170-A1 (AU)
Title: Process for preparing XPO1 inhibitors and intermediates for use in the preparation of XP01 inhibitors
Inventor: AUSTAD BRIAN CLINTON
IPC: C07D403/12
Filed: 2020-05-01
Abstract: The present invention provides an improved process for preparation of the (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid (referred to as compound of the structural formula (III)), which is a useful key intermediate for the synthesis of Selinexor ((Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide). The process comprises reaction of the compound of the structural formula (I) (as described herein) with the compound of the structural formula (II) (as described herein) in the presence of a catalyst, an organic base and an ether-containing solvent. The subsequent hydrolysis of the formed compound of the structural formula (IIIa) (as described herein) is performed without isolation of the compound of the structural formula (IIIa), providing compound of the structural formula (III) in high yield and stereoselectivity.
Patent AU-2020274717-A1 (AU)
Title: Composite biomaterials
Inventor: HICKEY RYAN
IPC: C12N5/07
Filed: 2020-05-14
Abstract: Provided herein are composite scaffold biomaterials including two or more scaffold biomaterial subunits, each including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure, the two or more scaffold biomaterial subunits being assembled into the composite scaffold biomaterial and held together via gel casting using a hydrogel glue; via complementary interlocking geometry of the two or more scaffold biomaterial subunits; via guided assembly based biolithography (GAB); via chemical cross-linking; or any combinations thereof. Methods for producing such scaffold biomaterials, as well as methods and uses thereof, are also provided.
Patent AU-2020283390-A1 (AU)
Title: Methods and apparatuses for patient-derived micro-organospheres
Inventor: SHEN XILING
IPC: C12M3/00
Filed: 2020-04-01
Abstract: Micro-Organosphers, including Patient-Derived Micro-Organospheres (PMOSs), apparatuses and methods of making them, and apparatuses and methods of using them. Also described herein are methods and systems for screening a patient using these Patient-Derived Micro-Organospheres, including personalized therapies.
Patent AU-2020291419-A1 (AU)
Title: Reusable urinary catheter kits
Inventor: MURRAY MICHAEL G
IPC: A61M25/00
Filed: 2020-06-10
Abstract: Kits are provided for storing, transporting, and sterilizing reusable urinary catheters. A reusable urinary catheter stored within a housing of the kit may be sterilized between uses using a sterilization fluid or sterilizing light. If the reusable urinary catheter is sterilized using a sterilization fluid, the housing may include a manually actuated or electromechanical pump to circulate the sterilization fluid through the housing. The reusable urinary catheter may include a funnel secured to a catheter shaft, with a plurality of lateral openings defined in the funnel, which provide fluid communication between an interior of the funnel and an external surface of the catheter shaft. By allowing fluid communication between the interior of the funnel and the external surface of the catheter shaft, the lateral openings allow for fluid sterilization of both internal and external surfaces of the catheter shaft.
Patent AU-2020325315-A1 (AU)
Title: Anti-NAMPT antibodies and uses thereof
Inventor: GARCIA JOE G N
IPC: C07K16/18
Filed: 2020-08-07
Abstract: Anti-nicotinamide phosphoribosyltransferase (NAMPT) antibodies, or antigen binding fragments thereof, are described, as well as methods for treating a subject having a (NAMPT)-associated local and/or systemic inflammatory disorder.
Patent AU-2020326589-A1 (AU)
Title: Materials and methods for multidirectional biotransportation
Inventor: GANESAN RAJKUMAR
IPC: A61P1/00
Filed: 2020-07-31
Abstract: A method is described for delivering a single domain antibody or a therapeutic molecule from an apical surface of a polymeric immunoglobulin receptor (pIgR)-expressing cell to a basolateral surface of the plgR-expressing cell comprising contacting the plgR-expressing cell with the single domain antibody or the therapeutic molecule, wherein the single domain antibody binds to plgR, and the therapeutic molecule comprises an agent and the single domain antibody. A method is also described for transporting such a therapeutic molecule to systemic circulation or lamina propria or gastrointestinal tract of a subject comprising administering the therapeutic molecule to the subject via oral delivery, buccal delivery, nasal delivery or inhalation delivery.
Patent AU-2020382545-A1 (AU)
Title: Energy efficient VPSA process with direct drive high speed centrifugal compressors
Inventor: ROSINSKI ANDREW C
IPC: B01D53/047
Filed: 2020-11-05
Abstract: The invention relates to a method and system for improving PSA/VPSA plant energy efficiency during times of reduced production demand and capital efficiency through optimizing feed, vacuum, and centrifugal product compressors to achieve lower energy consumption and lower unit gas product production cost. More specifically, the present invention relates to a new energy efficient PSA/VPSA turn down process and system which employs high speed direct drive centrifugal product compressor to achieve desired production. Significant lower energy consumption can be achieved by employing lower flow, and lower adsorption top pressure in the lower production range.
Patent AU-2020387990-A1 (AU)
Title: Methods of cancer treatment using anti-OX40 antibodies in combination with anti-TIM3 antibodies
Inventor: JIANG BEIBEI
IPC: C07K16/28
Filed: 2020-11-19
Abstract: Provided are methods of treating cancer or increasing, enhancing, or stimulating an immune response with non-competitive, agonist anti-OX40 antibodies and antigen-binding fragments thereof that bind to human OX40 (ACT35, CD134, or TNFRSF4), in combination with an anti-TIM3 antibody or antigen binding fragment thereof.
Patent AU-2020392128-A1 (AU)
Title: Formulations of ion channel modulators and methods of preparation and use of ion channel modulators
Inventor: MARTINEZ BOTELLA GABRIEL
IPC: A61K31/438
Filed: 2020-11-25
Abstract: The present invention is directed to, in part, compositions or dosage forms comprising fused heteroaryl compounds useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, neuromuscular disorders, trigeminal autonomic cephalalgia (TAC), migraine, cranial neuropathy or multiple cranial neuropathy, and cortical spreading depression (CSD)are also provided herein. In another aspect, the present invention provides a method of making ion channel modulators.
Patent AU-2020409711-A1 (AU)
Title: Synthesis of lactone derivatives and their use in the modification of proteins
Inventor: MORRIS ALEXANDER REDFERN
IPC: A61K47/54
Filed: 2020-12-18
Abstract: Site-specific modifications of proteins are desirable in biotechnological applications such as biopharmaceuticals, immunotherapy, vaccines, and are useful in chemical biology. Gluconoylation is a non-enzymatic, covalent, post-translational modification commonly observed on N-terminal His-Tags bearing proteins. We synthesized glucono-1,5-lactone derivatives, including azido variants for selective acylation. High yield acylation is achieved by simply mixing derivatives with target protein amidst diverse conditions of temperatures, aqueous buffers, excipients, or complex cell lysate.
Patent WO-2022087671-A1 (WO)
Title: Améliorations apportées ou relatives à la préparation et à la fourniture de canne à sucre à un broyeur de canne à sucre
Inventor: FITZMAURICE ALAN LEWIS
IPC: C13B10/10
Filed: 2021-10-28
Abstract: Une entrée de broyeur de canne est optimisée pour n'importe quelle condition de charge donnée et comprend un dispositif d'alimentation en amont du broyeur permettant de distribuer de manière régulable la canne en aval du dispositif d'alimentation afin de réduire les fluctuations de charge d'entraînement du broyeur. Un « éjecteur » (26) doté de lames d'extrémité incurvées assure une couverture complète sur toute la largeur du support de canne, et est entraîné dans le sens des aiguilles d'une montre à environ 175 tours par minute. Un protecteur de broyeur et d'écrasement en tandem magnétique retire le métal de la canne au-dessus d'une goulotte inclinée vers l'arrière (27). La goulotte comporte une fenêtre de visualisation (28) et un capteur de hauteur de canne (29). La goulotte dirigée vers l'arrière aide à ce que la cane frappe sa paroi avant (30) et la face de travail du dispositif de commande de hauteur de goulotte. Un rotor (31) de broyeur à dispositif d'alimentation à dents est situé dans un logement (32) de broyeur. Le logement (32) de broyeur a une configuration convolutée. Un dispositif d'alimentation (33) est posé directement au-dessus du logement (32) de broyeur, lequel dispositif d'alimentation comporte dans ce cas des roues (34) et (35) de dispositif d'alimentation à dents. Le dispositif d'alimentation fonctionne comme un déflecteur de vitesse pour le broyeur de façon à ce que la canne soit fournie à une vitesse optimale. Le débit à travers l'usine est basé sur la vitesse du dispositif d'alimentation.
Patent WO-2022104421-A1 (WO)
Title: Poignée de fusil harpon et fusil harpon
Inventor: ALAM RADWAN
IPC: A01K81/00
Filed: 2021-11-17
Abstract: L'invention concerne une poignée pour un fusil harpon et un fusil harpon complet. La poignée comprend un corps allongé s'étendant longitudinalement entre des extrémités avant et arrière opposées de celui-ci. L'extrémité avant du corps est conçue pour être adjacente à une extrémité arrière d'un canon d'un fusil harpon. Une partie d'une surface externe du corps comprend une surface de préhension, la surface de préhension étant disposée radialement autour d'un axe central et s'étendant longitudinalement dans la direction de l'axe central, l'axe central de la surface de préhension s'étendant sensiblement dans la même direction que l'axe longitudinal du canon du fusil harpon.
Patent AU-2021203836-A1 (AU)
Title: Methods and compositions for the activation of gamma-delta T-cells
Inventor: PAUZA CHARLES DAVID
IPC: G01N33/50
Filed: 2021-06-10
Abstract: The present invention relates generally to methods and compositions for gene therapy 
and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the 
treatment of various cancers and infectious diseases.
Patent AU-2021208776-A1 (AU)
Title: Radio frequency ablation catheter having function of moving guide wire
Inventor: DONG YONGHUA
IPC: A61B18/12
Filed: 2021-01-15
Abstract: A radio frequency ablation catheter having the function of a moving guide wire, comprising an electrode support (1), an elongated catheter main body (2) and a control handle (3) which are sequentially provided. The catheter main body (2) is provided therein with a cavity for the sliding of the moving guide wire (10). The distal end of the moving guide wire (10) passes through the catheter main body (2) and protrudes from the distal end of the electrode support (1), a soft guide wire (12) provided at the distal end of the moving guide wire (10) is always kept outside the electrode support (1), the proximal end of the moving guide wire (10) protrudes from the proximal end of the catheter main body (2) and enters the control handle (3), then, the proximal end of the moving guide wire (10) is fixed to a push member (8) provided on the control handle (3) or is fixed to a push member (8) provided outside the control handle (3), and the moving guide wire (10) is pushed forward or withdrawn under the action of the push member (8). By combining the moving guide wire (10) with the radio frequency ablation catheter, the radio frequency ablation catheter having the function of a moving guide wire (10) omits the action of withdrawing the moving guide wire (10) from the radio frequency ablation catheter, simplifying the operation of the moving guide wire (10), and facilitating movement of the radio frequency ablation catheter during surgery.
Patent AU-2021217126-A1 (AU)
Title: Arrangements for forming three-dimensional structures, and related methods thereof
Inventor: CHHAYA MOHIT PRASHANT
IPC: A61L27/00
Filed: 2021-02-03
Abstract: Embodiments relate to a method for forming a three-dimensional structure. The method includes determining one or more locations for positioning a sensing device based on structural coordinate information relating to a three-dimensional structure to be formed. The method further includes forming a portion of the three-dimensional structure based on the structural coordinate information. The method further includes positioning the sensing device at a location of the one or more locations.
Patent AU-2021221654-A1 (AU)
Title: Pliable explosive product and method of manufacture thereof
Inventor: MARTIN DREW ANTHONY
IPC: F42B3/02
Filed: 2021-08-25
Abstract: A pliable explosive product comprising a string of pliable explosive sections connected by a 
single detonating cord running through the sections along the length of the string, wherein the 
string comprises a toe end section and a plurality of subsequent sections, and wherein the toe 
end section is of greater diameter than the subsequent sections.
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Patent AU-2021231532-A1 (AU)
Title: Galacto-oligosaccharide having a terminal mannose residue, its preparation and application
Inventor: CAO LINQIU
IPC: A23L33/00
Filed: 2021-03-03
Abstract: The present invention provides a new type of galacto-oligosaccharide, having a mannose residue instead of a glucose residue at the reducing end. The invention also relates to compositions comprising this galacto-oligosaccharide, its preparation and use in nutritional compositions.