baber/WOPTO huggingface dataset:
Patent PT-1400628-E (PT)
Title: Embedded rail
Inventor: WOLFENDALE ROBIN
IPC: E01B21/00
Filed: 2003-09-10
Abstract: A rail track assembly comprises a concrete bed or beam 10 in which is embedded a rail 1 which is clad in an elastomer sheath 2, and coated within the sheath with a coating layer 3 of an electrically insulating and corrosion resistant material such as an epoxide or polyurethane resin. The running surfaces 16 are left exposed. A fabrication method comprises first abrading the surface of the rail, applying the coating 3, inserting the rail into the sheath 2 and casting the concrete bed about the sheathed rail. <IMAGE>
Patent PT-1474443-E (PT)
Title: Tolerogenic peptides from myelin basic protein
Inventor: WRAITH DAVID CAMERON
IPC: A61P25/00
Filed: 2003-01-30
Abstract: There is provided a peptide that is capable of binding to an MHC class I or II molecule without further processing (i.e., an apitope), which comprises a portion of the region 131-158 of myelin basic protein. In particular, there is provided an apitope which is selected from the following myelin basic protein peptides: 134-148, 135-149, 136-150, 137-151, 138-152, 139-153, 140-154. There is also provided the use of such a peptide in a pharmaceutical composition and a method to treat and/or prevent a disease using such a peptide.
Patent PT-1509600-E (PT)
Title: Plant thymidine kinases and their use
Inventor: MUNCH-PETERSEN BIRGITTE
IPC: A61K45/00
Filed: 2003-05-21
Abstract: This invention relates to novel plant thymidine kinases and their use in gene therapy. More specifically the invention provides novel thymidine kinases derived from tomato. In further aspects the invention provides novel polynucleotides encoding the tomato thymidine kinase of mutant thereof, vector constructs comprising the polynucleotide, host cells carrying the polynucleotide or vector, methods of sensitising cells to prodrugs, methods of inhibiting pathogenic agents in warm-blooded animals, methods for biocontrol of plants, methods of synthesizing monophosphates and pharmaceutical compositions comprising the plant thymidine kinases of the invention. In a preferred embodiment the invention provides a unique combination of a plant thymidine kinase and the nucleoside analog nucleoside analog AZT (3′-azido-3′-deoxythymidine) to treat abnormal cell growth.
Patent PT-1523911-E (PT)
Title: Spring core
Inventor: SCHMIDT GERD-UWE
IPC: A47C27/07
Filed: 2004-08-20
Abstract: The final assembly of a mattress often takes place far away from the spring producing factory, making the expenses for transport an important factor in particular in respect to the bulky, but lightweight quality of the item. Especially the strong helical springs (1) also used to sit on can be held during the transport in frames (2) made of carbon steel. The steel band used for the creation of the frames (2) is ideally approximately three times as wide as its thickness.
Patent PT-1525805-E (PT)
Title: Process of producing sterilised cooked rice packaged in containers
Inventor: FUKAYA TETSUYA
IPC: A23L5/10
Filed: 2004-10-04
Abstract: Sterilized cooked rice packaged in containers is produced by arranging on each of many shelves many containers each containing rice and cooking water, placing the shelves inside a retort and cooking the rice in each of the containers inside the retort at Fo value 0.1-1.5 by repeating a pressure increase inside the retort and a pressure reduction to cause the cooking water to boil at least once per minute.
Patent PT-1711169-E (PT)
Title: Extended release coated minitablets of venlafaxine hydrochloride
Inventor: BHATTACHARYA SAMPAD
IPC: A61K9/32
Filed: 2004-10-27
Abstract: The present invention relates to an extended release once daily pharmaceutical formulation comprising venlafaxine hydrochloride and pharmaceutically acceptable excipients. More particularly, the present invention relates to an extended release composition in the form of mini-tablets which are incorporated in hard gelatin capsules.
Patent PT-1712106-E (PT)
Title: Method and apparatus for providing end-to-end quality of service (qos)
Inventor: HSU LIANGCHI
IPC: H04L12/56
Filed: 2005-01-27
Abstract: An approach is provided for supporting end-to-end Quality of Service (QoS) control. A QoS profile identifier is generated that maps to a QoS parameter. The identifier is transmitted over the radio communication system to an end station, wherein the end station determines the QoS parameter based on the received identifier. The approach also provides an alert mechanism in which the end station transmits an alert message upon detecting a deviation from the QoS parameter.
Patent PT-1784169-E (PT)
Title: Polymeric adhesive matrix with salified carboxylic groups for transdermal use
Inventor: STEFANELLI PAOLA
IPC: A61K9/70
Filed: 2005-07-06
Abstract: Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a Tg lower than 0° C., whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention allow to prepare therapeutical systems for the controlled-release of active principles through the transdermal route, thus solving stability, solubility and/or bioavailability problems of the active ingredient within the matrix.
Patent PT-2093273-E (PT)
Title: Waterproof multiple rare-earth co-activated long-afterglow luminescent material
Inventor: ZHANG MING
IPC: C09K11/55
Filed: 2007-11-15
Abstract: The present invention relates to a waterproof multiple rare-earth co-activated long-afterglow luminescent material having its general chemical composition depicted by a formula aMO¢bAl 2 O 3 ¢cSiO 2 ¢dGa 2 O 3  : xEu¢yB¢zN, wherein a, b, c, d, x, y, and z are coefficients with the ranges of 0.5 ¤ a ¤ 2, 0.5 ¤ b ¤ 3, 0.001 ¤ c ¤ 1, 0.0001 ¤ d ¤ 1, 0.0001 ¤ x ¤ 1, 0.0001 ¤ y ¤ 1, 0.0001 ¤ z ¤ 1, M is Ca or Sr, N is Dy or Nd, wherein Sr (or Ca), Al, Si, Ga are main substrate matrix elements and Eu, B, Dy (or Nd) elements are activators. The waterproof multiple rare-earth co-activated long-afterglow luminescent material according to the present invention not only has advantage of a longer afterglow time, but also has water resistance greatly superior to rare-earth activated aluminate long-afterglow luminescent material in the prior art, and still keeps higher long-afterglow property after dipping into water for 60 hours, especially shows its superiority when working or used under the environment of dipping into water or dampness.
Patent PT-2113502-E (PT)
Title: Hydrazyde type compounds and the use thereof in pharmaceutical compositions for the treatment of cardiovascular diseases
Inventor: MARGUERIE GERARD
IPC: C07C251/86
Filed: 2005-01-31
Abstract: Hydrazide derivatives (I) and their acid addition salts are new. Hydrazide derivatives of formula (I) and their acid addition salts are new. R 1>, R 2>H, 1-6C alkyl or 1-6C tri- to hepta-fluoroalkyl; A : mono- or poly-cyclic aryl or heteroaryl; B : optionally substituted phenyl. [Image] ACTIVITY : Antilipemic; Antiarteriosclerotic; Vasotropic; Anorectic; Antidiabetic; Cerebroprotective; Hepatotropic. 2-Cyclopropyl-4-quinolinecarboxylic acid (2-hydroxy-4,6-dimethoxybenzylidene)hydrazide (Ia) gave 81% inhibition of lipoprotein (LDLox; not defined) accumulation in THP1 cells at a concentration of 2.5 mu M. MECHANISM OF ACTION : None given.
Patent PT-2177528-E (PT)
Title: Process for the preparation of mixtures of trifluoroacetyl glatiramer acetate using purified hydrobromic acid
Inventor: DOLITZKY BEN-ZION
IPC: C07K1/00
Filed: 2005-09-09
Abstract: The Subject invention provides an improved process for obtaining a mixture of polypeptides having nonuniform amino acid sequences, where each polypeptide consists essentially of alanine, glutamic acid, tyrosine and lysine where the resulting mixture of polypeptides comprises less than 0.3% brominated tyrosine and less than 1000 ppm metal ion impurities.
Patent PT-658232-E (PT)
Inventor: BOGEL HELMUT
IPC: B29C67/00
Filed: 1993-08-12
Abstract: A framework, in particular an at least partially hollow framework, has nodes and members. The nodes (14) are formed by at least a projection (30) on a hollow framework member (12) and by at least a further hollow member mounted and secured thereon. Also disclosed is a process for producing this framework and its use in land, air and water vehicles, in building construction, in civil and underground engineering, scaffolds, shelving systems and furniture.
Patent PT-688377-E (PT)
Inventor: CAROPRESO FRANK EDWARD
IPC: D21H21/20
Filed: 1994-02-24
Abstract: A method for repulping a wet strength paper is disclosed. Wet strength paper, which contains a wet strength resin, is agitated in water to form an aqueous slurry. An effective amount of a composition that contains a dry mixture of a persulfate and a base in the range of 90:10 to 10:90 is added either before or during agitation, and the slurry heated to produce pulp product for paper manufacture. The persulfate/base combination is capable of breaking down the wet strength resin and adjusting or maintaining the pH at a predetermined level without additional chemical treatment.
Patent PT-714418-E (PT)
Inventor: PAWELEK JOHN M
IPC: A01N43/38
Filed: 1994-08-11
Abstract: Synthetic melanins suitable for cosmetic uses are produced through oxidative polymerization of monomeric precursors that possess aromatic rings with ionizeable side groups. Agents that enhance adherence of the melanins to skin and hair are co-polymerized with the precursors to become part of the melanin molecules. Potential new precursors and adherence-enhancing agents are screened for efficacy by subjecting them to six separate synthetic procedures, and testing the resulting melanins for color, ultraviolet absorbance charcteristics, and substantivity (adherence) to skin and hair. Melanins of different colors can be blended together in cosmetic creams and lotions to complement the natural skin, eye, and hair colors of an individual. The synthetic procedures are amendable to industrial-scale production of cosmetic melanins. The materials reduce the incidence of solar damage to the skin.
Patent PT-885198-E (PT)
Inventor: THOMAS ANDREW PETER
IPC: A61K31/505
Filed: 1997-02-28
Abstract: The invention relates to quinazoline derivatives of formula (I) (wherein: R1 represents hydrogen or methoxy; R2 represents methoxy, ethoxy, 2-methoxyethoxy, 3-methoxypropoxy, 2-ethoxyethoxy, trifluoromethoxy, 2,2,2-trifluoroethoxy, 2-hydroxyethoxy, 3-hydroxypropoxy, 2-(N,N-dimethylamino)ethoxy, 3-(N,N-dimethylamino)propoxy, 2-morpholinoethoxy, 3-morpholinopropoxy, 4-morpholinobutoxy, 2-piperidinoethoxy, 3-piperidinopropoxy, 4-piperidinobutoxy, 2-(piperazin-1-yl)ethoxy, 3-(piperazin-1-yl)propoxy, 4-(piperazin-1-yl)butoxy, 2-(4-methylpiperazin-1-yl)ethoxy, 3-(4methylpiperazin-1-yl)propoxy or 4-(4-methylpiperazin-1-yl)butoxy; the phenyl group bearing (R3)2 is selected from: 2-fluoro-5-hydroxyphenyl, 4-bromo-2-fluorophenyl, 2,4-difluorophenyl, 4-chloro-2-fluorophenyl, 2-fluoro-4-methylphenyl, 2-fluoro-4-methoxyphenyl, 4-bromo-3-hydroxyphenyl, 4-fluoro-3-hydroxyphenyl, 4-chloro-3-hydroxyphenyl, 3-hydroxy-4-methylphenyl, 3-hydroxy-4-methoxyphenyl and 4-cyano-2-fluorophenyl); and salts thereof, processes for their preparation and pharmaceutical compositions containing a compound of formula (I) or a pharmaceutically acceptable salt thereof as active ingredient The compounds of formula (I) and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis
Patent PT-1019591-E (PT)
Inventor: VISSER DAVID DIRK
IPC: E04C2/30
Filed: 1997-11-28
Abstract: A building element (1) comprising an outer sheath and an inner core, the sheath being formed of a material having a greater tensile strength than compressive strength and the core having a greater compressive strength than tensile strength; wherein the outer sheath is longitudinally extending and has a first face (7) and a second face (8) which are spaced apart, first (9) and second (21) edges and a first and second end; wherein the first face (7) and the second face (8) are joined at the first (9) and second (21) edges to form the outer sheath as a continuous body, and wherein the first edge (9) and the second edge (21) are so shaped that the first edge (9) of one such building element (1) is adapted to locate in the second edge (21) of another such building element (1).
Patent PT-944855-E (PT)
Inventor: KROMAN FLEMMING
IPC: G02C5/00
Filed: 1997-12-11
Abstract: A pair of spectacles comprises two support elements (7) for engaging the nose of the wearer. Each support element comprises a pad (8) of an elastic material secured to a shank (10) with an enlarged head (11) adapted for retaining the support element relative to the rest of the spectacles by way of inserting the shank through said eyelet of the frame. According to the invention a peg (13) is inserted into the head end of the shank for providing a hard core inside at least part of the shank. Thus, easy mounting and safe retention are provided. The invention further comprises a blank for the manufacturing of the peg, and a method of manufacturing a pair of spectacles.
Patent PT-1032587-E (PT)
Title: Novel exendin agonist compounds
Inventor: PRICKETT KATHRYN S
IPC: C07K7/00
Filed: 1998-11-13
Abstract: Novel exendin agonist compounds are provided. These compounds are useful in treating diabetes and conditions which would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying.
Patent PT-924210-E (PT)
Inventor: TAMAI SATOSHI
IPC: A61P31/04
Filed: 1994-06-30
Abstract: Novel 3-Mercapto-1-(1,3-thiazolin-2-yl)azetidine derivatives represented by formula (IX) below or acid addition salts thereof <CHEM> wherein R is hydrogen, C1-C7 alkyl group which is unsubstituted or substituted by hydroxy, C1-C7 alkoxy or C1-C7 alkoxy-C1-C7 alkoxy group; group -COOR<1> (R<1> is hydrogen or C1-C7 alkyl group); or group -CONR<2>R<3> (R<2> and R<3> are, independently each other, hydrogen or C1-C7 alkyl and a process for producing these compounds.
Patent PT-1044427-E (PT)
Inventor: OTTERSTEIN KARL
IPC: G06K19/06
Filed: 1999-05-29
Abstract: The invention relates to a digital data carrier (1) with a carrier body (2) whose profile deviates from the standard outer diameter. The inventive digital data carrier is for playing in a standard CD-drive (6) which has a retractable tray (5) with a first receiving element (15) for data carriers with a larger standard diameter and a second receiving element (13) for data carriers with a smaller standard diameter. The digital data carrier has a centring aid on the side of the carrier body facing towards the tray, for centring in the second receiving element (13). Said centring aid consists of two ring pieces located opposite each other and adapted to the second receiving element (13).
Patent SG-22788-G (SG)
Title: Pyrrolidine derivatives
IPC: C07D207/27
Filed: 1988-04-05
Abstract: 2-(2-Oxo-1-pyrrolidinyl)acetic acids of the formula    <IMAGE>  III wherein R2 is hydrogen or lower alkyl and R11 is hydrogen, lower alkanoyl or another group readily cleavable by means of ammonia, are described. The compounds of formula III of the invention are useful to prepare the compound of formula I of the invention which are useful as medicaments, for example, in the form of pharmaceutical preparations.
Patent SG-56384-G (SG)
Title: Anti-inflammatory and immunoregulatory pyridines and pyrimidines
IPC: B29D99/00
Filed: 1984-08-13
Abstract: A series of 4-(2-hydroxyethylthiomethyl)pyridines and related compounds, and their pharmaceutically acceptable acid addition salts, having antiinflammatory and immunoregulatory activity are disclosed. Preferred compounds include 4-(2-hydroxyethylthiomethyl)pyridine itself, as well as 4-(2-hydroxyphenylthiomethyl)pyridine, 4-(2-hydroxy-1-propylthiomethyl)pyridine, 4-(3-hydroxy-2-butylthiomethyl)pyridine, 4-(2-hydroxyethylthiomethyl)pyrimidine, the acetate esters corresponding to the above compounds, and 4-(2,3-dihydroxy-1-propylthiomethyl)pyridine.
Patent IE-42626-L (IE)
Title: 6-arylpyrroloimidazoles
IPC: C07C205/04
Filed: 1976-01-22
Abstract: 1513742 2,3,6,7 - Tetrahydro - 5H - pyrrolo- (1,2 - a)imidazoles IMPERIAL CHEMICAL INDUSTRIES Ltd 16 Jan 1976 [31 Jan 1975] 4303/75 Heading C2C Novel Compounds I and their acid addition salts in which R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP> and R<SP>5</SP> are H or C 1-4 alkyl, R<SP>4</SP> is H or C 1-4 alkyl and Ar is optionally substituted aryl or Ar represents aryl which has a substituent adjacent the linking position which substituent together with R<SP>4</SP> represents C 1-3 alkylene and the aryl moiety may be further substituted are prepared by cyclizing a Compound II, III, IV, V, VI or VII. in which X is Hal, OH or a sulphonyloxy radical or hydrolysis and decarboxylation of an ester VIII or IX in which R<SP>6</SP> is C 1-6 alkyl and if desired (a) reducing NO 2 to NH 2 or acylating NH 2 in a compound in which Ar bears such substituents (b) forming a salt or (c) resolving a racemic compound into its enantiomers. Compounds II, III or IV are prepared by reacting a Compound X where Z is OEt with a compound XI or a Compound XIa Compounds X are prepared by reacting a pyrrolidone with EtOH under acidic conditions. Compounds XII are prepared by methods disclosed in Specification 1,140,188. Compounds V are prepared by reacting pyrrolidone XII with a Compound XI or XIa or when R<SP>1</SP>=H with X-CHR<SP>2</SP>-CN followed by reduction. Compounds I have anti-hypertensive activity and may be used in pharmaceutical compositions for administration orally or parenterally. The compositions may further contain vasodilators (glyceryl nitrate, pentaerythritol tetranitrate and isosorbide dinitrate); diuretics (chlorothiazide), other hypotensive agents (reserpine, bethanidine and guanethidine) and #-adrenergic blocking agents (propranolol).
[GB1513742A]
Patent IE-40759-L (IE)
Title: Stoma irrigating apparatus.
IPC: A63C9/086
Filed: 1975-03-06
Abstract: The present invention provides a stoma irrigating system including an irrigating cone which is soft on the inserted apex end but firm on the base end and is easily cleansed, a reservoir for irrigating fluid, a bag to be secured to the body of an ostomy patient, the bag having an opening surrounding the stoma of the patient, and with the bag having closeable means which permits the irrigating cone to be inserted into the stoma, and to which cone a tube communicating with the reservoir may be attached to direct irrigating fluid into the stoma and hence into the intestinal tract of the patient.
[US3910274A]
Patent IE-44652-L (IE)
Title: Processing glass sheets
IPC: C03B35/20
Filed: 1977-03-16
Abstract: A succession of glass sheets are processed, for example by heating, bending and toughening in the production of windshield glasses. Each glass sheet is suspended vertically in an elongated furnace from a transport member, and when hot is lifted from the furnace into the lowermost of a vertical series of treatment stations, for example a bending station followed by a toughening station, by a lifting device which engages the transport member. Subsequently the transport member is supported independently of the lifting device at a level above the furnace so that the lifting device can then be lowered to lift the next glass sheet from the furnace.
[US4094659A]
Patent IE-850925-L (IE)
Title: Removable labels
IPC: C09J7/38
Filed: 1985-04-12
Abstract: Removable label stock and a process for its preparation. The stock (10) comprises discontinuous emulsion adhesive segments (12) on at least a portion (14) of one side of a face thereof. The amount of adhesive present for contact with a smooth surface is from about 10 percent to about 30 percent of the amount of adhesive which would have occupied the portion if the face stock were continuously coated with the adhesive. The emulsion adhesive segments have an average height, relative to the surface of the face stock, of from about 15 to about 35 microns; a room-temperature storage modulus of from about 2 x 10<5> to about 1.5 x 10<6> Pascal at a deformation rate of about 10<4> radians per second, a room-temperature storage modulus of from about 4 x 10<4> to about 5 x 10<5> Pascal at a deformation rate of about 10<2> radians per second, a room-temperature storage modulus of from about 1 x 10<4> to about 8 x 10<4> Pascal at a deformation rate of about 10<-2> radian per second, and a room-temperature storage modulus of from about 6 x 10<3> to about 7 x 10<4> Pascal at a deformation rate of about 10<-3> radian per second; a 180<o> peel strength on a stainless steel panel, having a roughness of about 0.5 micro-inch, of from about 0.5 pound to about 2 pounds per inch at a coating weight of about 40 grams/m<2>; and a glass-transition temperature of less than 250<o> Kelvin.
Patent FI-830640-L (FI)
Inventor: QUARROZ DANIEL
IPC: C07D213/73
Filed: 1983-02-25
Abstract: Procedure for producing 2-aminopyridines having general formula: <IMAGE>   from 2-pyridine carboxylic acid-N-oxides having the formula:   <IMAGE>  wherein R is H or a -COOH group or an alkyl group having C1 to C8 or an aryl group, and n is a number between 1 and 4. The 2-pyridine carboxylic acid-N-oxide is converted with a lower aliphatic carboxylic acid anhydride and a tertiary amine in the presence of a carboxylic acid nitrile. The conversion product is hydrolyzed to the 2-aminopyridine compound.
Patent FI-853308-L (FI)
Inventor: LOEBEL KLAUS-DIETER
IPC: A61K47/00
Filed: 1985-08-29
Abstract: An aqueous injection solution contains 1-25% by weight of 2-hydroxy-N,N,N-trimethyl-ethanaminium salt of 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1) and, based on this salt, 5-8% by weight of propionic acid.
Patent IE-811010-L (IE)
Title: Acylanilides.
IPC: C07C317/50
Filed: 1981-05-07
Abstract: Novel 3,4-disubstituted-N-acylanilines of the formula:  <IMAGE> wherein R1, R2 and ring A are defined in claim 1; wherein R3 is hydrogen or alkyl of up to 4 carbon atoms, or is joined to R5 as stated below; wherein R4 is alkyl of 2 to 4 carbon atoms, or has the formula -CX1X2X3 wherein X1, X2 and X3, which may be the same or different, each is hydrogen, fluorine or chlorine; wherein R5 is hydrogen, hydroxy or alkoxy or acyloxy each of up to 15 carbon atoms, or is joined to R3 to form an oxycarbonyl group such that together with the  <IMAGE>  part of the molecule it forms an oxazolidinedione group; and wherein R6 is hydrogen or halogen. These compounds possess antiandrogenic activity and are useful for the treatment of androgen dependent or prostatic diseases. Representative of the compounds is 3,4-dichloro-N-(2-hydroxy-2-p-nitrophenylpropionyl)aniline. Also disclosed are processes for the manufacture of the compounds and pharmaceutical and veterinary compositions containing them.
Patent IE-881031-L (IE)
Title: Apparatus for attaching a catheter to a wound drainage bag
IPC: A61J1/05
Filed: 1988-04-07
Abstract: Apparatus for attaching a catheter to a bag includes a pair of coupling rings (10, 20) for trapping a part of the bag wall between them. A cutter having a blade of circular or closed loop form makes a cut in the trapped wall and an elastomeric member for gripping a catheter is connectable to the cutter or to one of the rings. The catheter is inserted in the elastomeric member and through the rings, the member serving as a gaiter.
[EP0286334A2]
Patent IE-37882-L (IE)
Title: Protection of parts of aluminium cell
IPC: G01K1/08
Filed: 1973-07-05
Abstract: Method of protection of electrically conducting parts in fluoride melts through which direct current flows in the electrolysis of aluminum oxide, comprising applying such an electrical potential to said parts that the direct current flowing through the fluoride melt cannot emerge from the parts at any place within the fluoride melt.
[US4124465A]