baber/WOPTO huggingface dataset:
Patent CZ-291323-B6 (CZ)
Title: Azaspirodecane derivatives, process of their preparation and medicament based thereon
Inventor: ADAM GEO
IPC: C07D401/04
Filed: 1999-06-08
Abstract: In the present invention there are disclosed azaspirodecane derivatives of the general formula I, in which Re1 represents cycloalkyl containing 6 to 10 carbon atoms being optionally substituted with alkyl having 1 to 6 carbon atoms or -C(O)O-alkyl, containing 1 to 6 carbon atoms, decahydronaphthalen-1-yl, decahydronaphthalen-2-yl, indan-1-yl or indan-2-yl, being optionally substituted with alkyl with 1 to 6 carbon atoms, decahydroazulen-2-yl, bicyclo[6,2,0]dec-9-yl, acenaphthen-1-yl, 2,3-dihydro-1N-phenalen-1-yl, 2,3,3a,4,5,6-hexahydro-1N-phenalen-1-yl or octahydroinden-1-yl, Re2 represents hydrogen, alkyl having 1 to 6 carbon atoms, =O or phenyl being optionally substituted with alkyl with 1 to 6 carbon atoms, a halogen or alkoxy containing 1 to 6 carbon atoms, A denotes cyclohexyl or phenyl, X represents -CH(OH)-, -C(O)-, -CHRe3-, CRe3=, -O-, -S-, -CH(COORe4)- or -C(COORe4)=, Y denotes -CHi2-, -CH=, -CH(COOe4)-, -C(COORe4)= or -C(CN)-, Re3 is hydrogen or alkoxy having 1 to 6 carbon atoms, Re4 represents  alkyl having 1 to 6 carbon atoms, cycloalkyl with 6 to 10 carbon atoms, phenyl or benzyl and either a or b is an optional further bond, in the form of a racemic mixture and their corresponding enantiomers and their pharmaceutically acceptable acid addition salts. The above described derivatives are intended for treating diseases connected with orphanine FQ (OFQ) receptor, which diseases comprise psychiatric, neurologic a physiologic disorders such as anxiety, stress disorders, depression, trauma, loss of memory due to Alzheimer's disease or another dementia, epilepsy and spasms, acute and/or chronic pain states, abstinence symptoms connected with withdrawal of addictive drugs, water balance control, Nae+ excretion, arterial blood pressure disorder and a metabolic disorder such as obesity.
Patent CZ-297954-B6 (CZ)
Title: Ziprasidone-based pharmaceutical composition and process for preparing large crystals of ziprasidone hydrochloride monohydrate
Inventor: BUSCH FRANK ROBERT
IPC: A61K47/26
Filed: 1999-06-14
Abstract: In the present invention, there is disclosed a pharmaceutical composition comprising crystalline ziprasidone free base or crystalline ziprasidone hydrochloride particles having a mean particle size equal to or less than about 85 microns and a pharmaceutically acceptable diluent or carrier. There is also disclosed a process for preparing large crystals of ziprasidone hydrochloride monohydrate, comprising the steps of: 1) dissolving ziprasidone free base in a solvent comprising tetrahydrofuran and water, in a volume ratio of about 22 to 35 unit volumes of tetrahydrofuran to about 1.5 to 8 volumes of water; 2) heating the solution resulting from step (1); 3) adding hydrogen chloride to the solution resulting from step (2); and 4) cooling the solution resulting from step (3).
Patent CZ-288848-B6 (CZ)
Title: Shut-down mechanism of glass forming machine
Inventor: JANDIK JOSEF
IPC: C03B9/453
Filed: 1996-10-17
Abstract: In the present invention there is described a shut-down mechanism of a glass forming machine comprised of a drive, interconnected by means of transmissions with a shifting element, whereby the drive consists of a first driving unit (1) and a second driving unit (2), which both are arranged on a foundation plate (3) in such a manner that their output shafts (4, 7) are parallel to each other. The output shaft (4) of the first driving unit (1) is coupled by means of a first transmission (5) with a hollow shaft (6) that is rotatably mounted on the foundation plate (3) and through the center of which passes the output shaft (7) of the second driving unit (2). The hollow shaft (6) supports a parallelogram consisting of a driver (8), at least two cranks (11) and the shifting element (12). In the driver (8), there are rotatably mounted at least two pins (9), which are interconnected by means of a second transmission (10) with the output shaft (7) of the second driving unit (2). Each pin (9) su
Patent SK-284089-B6 (SK)
Title: Printing machine with a cleaning device for printing carrier being fed
Inventor: MARKS MICHAEL
IPC: B41F23/00
Filed: 1998-07-24
Abstract: Printer with cleaner for sheet or length of printing carrier The cleaner has a compressed air pipe (1) possessing air-outlets with a diameter of 2 - 4, preferably 2.5 - 3 millimetres and pointing towards the conveyor web carrying the printing carrier. The air outlets extend at right angles to the direction of travel of the printing carrier. The compressed-air pipe is positioned in the middle inside a slot-shaped nozzle (2) connected to a vacuum fan (10). Part-slots are positioned on both sides of the compressed air pipe. The slot-shaped nozzle including the width of the compressed air pipe has a total width of 15 to 25 millimetres. the air outlets are spaced apart by 7 - 15, preferably 8 - 10, millimetres.
Patent SK-282137-B6 (SK)
Title: Device for measuring the quantity of heat supplied by a heating body
Inventor: KLEIN JOACHIM
IPC: G01K17/06
Filed: 1994-12-02
Abstract: The thermometer probes (7,8) communicate with the radiator (1) in a heat conducting connection. The amount of heat radiated from the radiator is computed from the measurement values of the two thermometer probes (7,8). The thermometer probes (7,8) are fitted in direct contact with the surface of the radiator. A curve is extrapolated from the probe values using a computer, which corresponds to the expected temp. profile of the radiator (1), and from which the amount of heat radiated from the radiator is computed.
Patent CZ-299501-B6 (CZ)
Title: Device for differential measurement of warm service water
Inventor: SAUER JAROSLAV
IPC: G01K17/06
Filed: 2005-04-15
Abstract: Warm water is supplied through a supply pipe via a supply sensor (11) of amount of water delivered to the object. Unused water flows back and returns through a recirculation piping to a source via a circulation sensor (12). An evaluation unit (15), forming part of the system, evaluates received pulses from the sensors (11 and 12), and transmits them to calorimetric units (13, 14). After arrival of a pulse of the circulation sensor (12) to the input ,BÆÆ of the evaluation unit (15) a flag is set for cancellation of a pulse on the input ,,A'' coming from the supply sensor (11). After arrival of the pulse ,,A'' the evaluation unit (15) verifies the flag setting and if the flag is set, the pulse ,,A'' is cancelled. Otherwise, addition and transfer to the calorimetric unit (13) take place. All pulses ,,B'' of the circulation sensor (12) are communicated via the evaluation unit (15) to the calorimetric unit (14). The supply sensor (11) of amount of water delivered to the object is mounted on the supply pipe, which sensor exhibit within the region of through flow Qt a longer period of pulses if compared with the circulation sensor (12).
Patent CZ-304301-B6 (CZ)
Title: Process for preparing magnetically conducting powders by making use of cavitation and apparatus for making the same
Inventor: CELKO LADISLAV
IPC: B22F9/00
Filed: 2012-09-19
Abstract: Process for preparing magnetically conducting powders is based on the principle of controlling a liquid flow in a cavitation line (1), where pulse pressure waves are generated within a nozzle (5) causing thus a cavitation cloud and implosion of cavitation bubbles with intensity of up to ultrasonic frequency of 24 kHz. The pulse pressure waves act on the surface of a material (6) to thereby causing liberation of particles (61) with particle size in the order of micrometer or nanometer units. The material (6) particles (61) are taken away from the nozzle (5) by a liquid medium into a collecting chamber (7), where they are trapped through the mediation of a magnetic element (8). Apparatus for carrying out the above-described process consists of a cavitation line (1) with a tank (2) for liquid built-in by means of a connecting pipe (11). The apparatus further comprises at least one pump (3), at least one shut-off valve (4) and at least one cavitation nozzle (5) comprised of a confuser (51) a cavitation chamber (52) and a diffuser (53), whereby said cavitation chamber (52) is adapted for placement of the material (6). For trapping the material (6) particles (61) separated by cavitation, the cavitation line (1) according to the present invention is provided with at least one collecting chamber (7), and a magnetic element (8) situated along the collecting chamber (7).
Patent CZ-308394-B6 (CZ)
Title: Headset for measuring the voice field
Inventor: GUŠTAR MILAN
IPC: H04R1/08
Filed: 2018-12-21
Abstract: The headset for measuring the voice field allows the voice field in front of the mouth to be measured, which is defined by the methodology of measuring the voice field, independently of the movements of the head and body of the examined person. The device consists of a headband holder (1) with an adjustable microphone (2) attached to the head cross (3). The headband (1) is in sections that adapt to the physiognomy of the person and the desired position of the microphone (2). The sections L of the sliding guide (4) and P of the sliding guide (5) with the sleeves (6) extend from the left and right sides. In the rear of the head, a 180° section of a semicircle (7) with an opening (8) for the microphone cable (9). In front of the person there is a section of 60° of a circular section (10) with a front section (11). The continuation L of the sliding guide (4) is a straight section (12) with an arc of 35° of the circular section (13) from the medial plane. Here, the sections on the left and right are firmly connected. The right here has a P end (14). The left one continues with the microphone holder (15) and the 180° microphone arc (16) downwards, where the microphone (2) is in the L hole (17).
Patent CZ-309499-B6 (CZ)
Title: Wire winding equipment and wire treatment system
Inventor: UEMOTO TOSHIFUMI
IPC: B65H54/00
Filed: 2020-12-21
Abstract: The wire winding device (100) includes a rotating shaft (110) of a rotating body and a rotating body for winding the wire (10) by rotation. The rotating body includes a rotating drum (120) rotating around the rotating shaft (110) of the rotating body, several wire support members (121) for supporting the wire (10), and several first spacers (240) on the rotating body on a stand (250) for the supporting elements (121). The first spacers (240) are adjustable in the rotating body to the first position and the second position. The first spacer (240) in the first position winds the wire (10) with the first winding diameter onto the rotating body outside the first spacer (240). The first spacer (240) in the second position winds the wire (10) with the second winding diameter onto the rotary body through the first spacer (240), the second winding diameter being larger than the first winding diameter.
Patent CZ-309853-B6 (CZ)
Title: A grenade launcher
Inventor: ZÁHORA JOSEF
IPC: F41C27/06
Filed: 2022-10-04
Abstract: The grenade launcher includes a barrel (10), a base (3) of the trigger mechanism and a breech (2). The base (3) of the trigger mechanism is adapted for mounting on the host clamping interface (1) and, on the opposite sides of the base (3) of the trigger mechanism, guide rails (5, 8) for sliding the barrel (10) are arranged. The host clamping interface (1) is clamped between the breech (2) and the base (3) of the trigger mechanism, and the breech (2) is provided with a cavity (11) that surrounds one of the guide rails (5) and the inner wall of the cavity (11) is pressed against this guide rail (5) by a catch (4), which can be inserted between this guide rail (5) and the wedge-shaped opposite inner wall of the cavity (11), and a pin (6), which is slidably mounted in a transverse recess in the breech (2) and equipped with a pressure spring (7), rests on this guide rail (5) from the inner side.
Patent CZ-298360-B6 (CZ)
Title: Installation kit for conduits
Inventor: BUHLA MICHAEL
IPC: E03D9/10
Filed: 2000-09-21
Abstract: In the present invention, there is disclosed an installation kit (1) for conduits, particularly for water mains being provided with a control rod (4) terminating close to a road cover. The control rod (4) lower end, having the form of a connecting sleeve (3), coupled in detachable manner with a conduit closure spindle. The control rod (4) is accommodated within a sleeve tube (5), whereby the installation kit (1) comprises a cover (8) of the sleeve tube (5) that centers the control rod (4) and that has a head section (9) fixing the sleeve tube (5) relative to the control rod (4) and being supported on the sleeve tube (5). The cover (8) further comprises a sliding disk (10) connected with the control rod (4) and turning relative the sleeve tube (5). Said head section (9) and the sliding disk (10) are coupled with each other by a latch connection. The head section (9) is provided with flexibly mounted and/or performed locking noses (2) and the sliding disk (10) is provided with counter-hooks (7), the shape and position of which correspond to the locking noses (2).
Patent CZ-301779-B6 (CZ)
Title: Rotary locking cylinder, key and modular system
Inventor: KELLER ERNST
IPC: E05B9/04
Filed: 2001-01-09
Abstract: In the present invention, there is disclosed a rotary locking cylinder (1) for a safety lock comprising a housing (5) and at least one armature (8) having a key channel (27) with tumblers which are provided to rotationally release the armature (8) with an associated key (17), with a driver (6) and with at least one extension element (3) attached to the active part (2) of the rotary locking cylinder(1), which has a housing (5) and a rotatable insert (9), wherein the invention is characterized in that least one extension element (3) is attached at a distance from the driver (6) outside on the active part (2) and in that the key (17) shank (19) is extended substantially to the length (A) of this extension element (3). There is also disclosed a corresponding key (17) for the above-described rotary locking cylinder (1) having a shank (19) with a front active part (20) and another part (21) between this active part (20) and a key (17) grip (18). Further disclosed is a modular system with several rotary locking cylinders (1), characterized in that the lengths (A) of the extension elements (3) and correspondingly the lengths (B) of the associated keys (17) are different.
Patent CZ-306327-B6 (CZ)
Title: Controlled release composition and process for preparing thereof
Inventor: YAMAMOTO KAZUMICHI
IPC: A61P35/00
Filed: 2002-06-28
Abstract: In the present invention, there is described a controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time. The controlled release composition of the present invention comprises: (1) an LH-RH luteinizing hormone releasing hormone derivative or a salt thereof in an amount of about 3 to about 24 percent by weight based on the total composition weight; and (2) a polymer composed only of lactic acid or salt thereof having a weight-average molecular weight of 17 000 to 26 000 in which the content of polymers having molecular weights of 5000 or less is about 5 percent by weight or less. The above-described pharmaceutical composition is useful for the use as a prophylaxis or medicament for the treatment of prostatic cancer, prostatic hyperplasia, endometriosis, uterine myoma, uterine fibroma, precocious puberty, and dysmenorrhea or breast cancer or as a contraceptive agent.
Patent SK-284893-B6 (SK)
Title: Triazepinones, process for their preparation and their therapeutic application
Inventor: RUGGIERO DANIEL
IPC: A61K31/00
Filed: 1999-01-11
Abstract: Triazepine derivatives of formula (I) and their pharmaceutically acceptable salts are described. Process for their preparation, in which a alpha-ketoaldehyde of formula (II) is reacted with a biguanide of formula (III) is described, too. Triazepinones are useful for preparing medicine for treatment of diabetes and its complications.
Patent AT-500379-B8 (AT)
IPC: C12N15/09
Filed: 2001-02-02
Granted: 2009-08-15
Abstract: The invention relates to antibodies with a specificity to an abnormally truncated form of tau protein, which is conformationally different from normal tau, and does not bind to normal tau protein, conformationally different tau proteins ("tauons") and diagnostic and therapeutical aspects in relation to Alzheimer's disease and related tauopathies.
Patent BR-PI0013875-B8 (BR)
Inventor: DEGELMANN HANSPETER
IPC: A23L27/30
Filed: 2000-09-09
Abstract: The present invention relates to an improved method of producing agglomerates and compressed products containing isomaltulose and/or hydrogenated isomaltulose.
Patent BR-PI0520870-B8 (BR)
Inventor: ESMIR GUNIC
IPC: C07D249/08
Filed: 2005-08-25
Abstract: A series of S-triazolyl ±-mercaptoacetanilides having general structure (I) are provided, where Q is CO 2 H, CONR 2 , SO 3 H,or SO 2 NR 2 . The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.
Patent BR-PI0812593-B8 (BR)
Title: Sensor de posição angular e método para determinar posição angular
Inventor: MARK ZAK
IPC: G01P3/487
Filed: 2008-06-06
Abstract: SENSOR DE POSIÇÃO ANGULAR. A invenção refere-se a um sensor de posição angular (24) e um método que se vale de um conjunto estacionário circular de sensores de hall (18) e um conjunto giratório circular de magnetos (16) dispositivos em torno de um eixo geométrico comum (22). Utiliza-se uma leitura periódica e simultânea de todas as saídas dos sensores de hall para determinar a velocidade angular.
Patent BR-PI1001316-B8 (BR)
Title: instalação de tratamento térmico de um fluxo de ar
Inventor: PHILIPPE VINCENT
IPC: B60H1/00
Filed: 2010-04-19
Abstract: instalação de tratamento térmico de um fluxo de ar. a invenção se refere a uma instalação de tratamento térmico de um fluxo de ar, compreendendo meios de mistura (20) para canalizar o fluxo de ar para meios de tratamento térmico (11, 12a, 12h) do fluxo de ar para obter um fluxo de ar misturado e meios de distribuição (29) do fluxo de ar misturado. a instalação de tratamento térmico comporta um alojamento único apto a receber indiferentemente: meios de mistura (20) e meios de distribuição (29) acoplados mecanicamente comandados por um órgão de comando (60) único, meios de mistura (20) e meios de distribuição (29) desacoplados mecanicamente respectivamente comandados por órgãos de comando (60a, 60b) independentes.
Patent AU-2009212311-B8 (AU)
Title: Modified leptin polypeptides and their uses
Inventor: KRAYNOV VADIM
IPC: A61K38/17
Filed: 2009-02-05
Granted: 2013-05-30
Abstract: Modified human teptin polypeptides and uses thereof arc provided.
Patent BR-112015001728-B8 (BR)
Title: composições de condicionador
Inventor: CHRISTIA CASUGBO
IPC: A61K8/34
Filed: 2013-07-24
Abstract: composição de condicionador trata-se de composição de condicionador que compreende de 0,4 a 8% em peso de álcool graxo que tem de 8 a 22 carbonos, de 0,1 a 2% em peso de componente de tensoativo catiônico, água e em que a composição tem uma massa de extração de 1 a 250 g.
Patent EP-2196199-B9 (EP)
Inventor: KNIPPER DR MARLIES
IPC: A61K31/00
Filed: 2006-01-19
Granted: 2014-12-31
Abstract: Use of a compound (I) interacting with brain-derived nerve growth factor (BDNF)-signal transduction cascade for the production of a medicament to treat phantom phenomena of acute tinnitus and/or phantom pain in human or animal. Independent claims are also included for: (1) diagnosing phantom phenomena of the acute tinnitus and/or phantom pain in human or animal, comprising supplying a biological sample, determining the level of the expression of BDNF in the biological sample, comparing the level with a reference value from a healthy organism, and correlating a level lying over the healthy organism with a positive diagnosis; and (2) treating phantom phenomena of the acute tinnitus and/or phantom pain in human or animal, comprising supplying a medicament that exhibits a substance interacting with BDNF signal transduction cascade, and applying the medicament locally to the organism, and optionally repeating the method. ACTIVITY : Auditory; Analgesic. MECHANISM OF ACTION : Brain-derived nerve growth factor (BDNF)-signal transduction cascade blocker; BDNF-signal transduction cascade inhibitor; Gamma aminobutyric acid receptor agonist; L-type-Ca ++>-channel antagonist; Cyclic adenosine monophosphate response element binding protein (CREP) antagonist; Glutamate antagonist; Mitogen activated protein-kinase-inhibitor; Calmodulin-dependent kinase-inhibitor; Tyrosine kinase linked receptor (trkB) antagonist. The ability of (I) to inhibit BDNF-signal transduction cascade was tested in cochlea. (I) Significantly removed the expressions of BNDF Exon-IV.
Patent EA-030168-B9 (EA)
Title: Method for monitoring operative conditions of thermal and/or catalytic cracking plants and related apparatus
Inventor: BUCCOLINI MARCO
IPC: G01N21/49
Filed: 2013-10-30
Abstract: The thermal conversion and/or catalytic plants, which can be found in the productive cycle of a refinery, are aimed at the utilization of the residues of the distillation of petroleum, otherwise destined for bitumen or combustible oil (products notoriously of low commercial value), so as to convert these products, in part, into lighter products of greater value. The conversion makes it possible to obtain considerable amounts of distilled products, such as gas, benzene, kerosene and diesel oil. The conversion process is carried out so as to maximize the yield of distilled products, thus lowering the overall yield of heavy residues. Adjustment of the operative parameters of the plants described above for the purpose of maximizing the yield of light products and managing the plants with controlled fouling conditions is carried out by means of methods for measuring aggregated asphaltenes and particles of carbon suspended in the bottom residue produced. The present invention proposes an improved procedure for determining the tendency of the bottom fluid to form fouling in determined plant conditions which definitively makes it possible to obtain better yields of light distillates, better control of the fouling occurring in the plant, and therefore a reduction of the associated energy consumption. In addition, the new procedure described in the patent makes it possible to determine on-line the tendency for fouling inasmuch as the analyzed sample does not require any handling.
Patent AU-2017294925-B9 (AU)
Title: Device for discharging multi-component adhesives onto a granular mixture, discharging method, and use of the device
Inventor: HUERLIMANN ADRIAN
IPC: B61D15/00
Filed: 2017-04-19
Granted: 2022-11-10
Abstract: The device for discharging multi-component adhesives consisting of at least two fluid components (A, B) onto a granular ballast bed (6) of a railway rail section (4) consists of at least two separate carriages, preferably three carriages (1, 2, 3). The carriages can be loaded into a vehicle or a trailer (48) by only two people in that the interior of the vehicle or the trailer is equipped with rails (50, 51) on which the carriages (1, 2, 3) can be rolled. Thus, the carriages can be transported on roadways so as to be brought to the location of use quickly and be put into operation, wherein the carriages are placed on the tracks (4) of the railway from the trailer (48) via retractable rails (51). The device allows adhesives to be applied onto a ballast bed (6) over long distances in a fully automated manner such that all specifications are met and the ballast bed is adhered such that normal train traffic can continue. The entire device can be loaded, transported, unloaded on-site, and put into operation by only two people.