baber/WOPTO huggingface dataset:
Patent RU-2769513-C2 (RU)
Inventor: TYKOCINSKI MARK L
IPC: C07K19/00
Filed: 2018-01-04
Granted: 2022-04-01
Abstract: FIELD: biotechnology. 
     SUBSTANCE: invention relates to fusion proteins PD1-4-1BBL, and can be used in medicine for treating cancer, cells of which express PD-L1. Constructing a fusion protein PD1-4-1BBL in the form of a homotrimer, containing at its N-end the amino acid sequence of programmed death 1 (PD1), and at its C-end amino acid sequence of ligand 4-1BB (4-1BBL), connected by means of linker from one glycine. 
     EFFECT: invention enables to obtain a fusion protein which is capable of binding PD-L1 and 4-1BB, activating said 4-1BB signaling pathway in a cell, expressing said 4-1BB and co-stimulation of immune cells expressing said 4-1BB. 
     11 cl, 1 tbl, 12 ex, 13 dwg
Patent RU-2759261-C2 (RU)
Inventor: PIMENOV ANDREJ BORISOVICH
IPC: G01F1/74
Filed: 2019-09-09
Granted: 2021-11-11
Abstract: Изобретение относится к технологии измерения расхода, включающей в себя системы для использования при измерении объемов добычи, включая двухфазную смесь из отдельных фаз, например смесь, содержащую нефтяную и газовую фазы. Техническим результатом изобретения является возможность разделения газово-жидкостной смеси непосредственно внутри измерительного трубопровода и измерение жидкой и газовой фазы, без использования сепаратора, разделения и сведения потоков отдельными трубопроводами. Указанный технический результат достигается за счет того, что разделяют поступающий многофазный поток на жидкий и газовый компонент с помощью вихревого потока, для чего используют геликоидальную турбину, которую вставляют внутрь измерительного трубопровода на оси, обеспечивая ей вращение с помощью двигательной установки, причем за турбиной по ходу движения потока соосно основному трубопроводу размещают трубу меньшего диаметра, которой образуют зазор между своей внешней поверхностью трубы меньшего диаметра и внутренней поверхностью трубопровода; на внешней или внутренней трубе размещают расходомеры жидкой фазы; а на выходе из внутренней трубы, где происходит естественное смешивание жидкой и газовой фаз и их совместное движение, либо до турбины, размещают расходомеры общей фракции; по разнице показаний между расходомерами определяют объем газовой составляющей смеси. 2 н. и 1 з.п. ф-лы, 1 ил.
Patent RU-2752629-C2 (RU)
Title: Panel and coating
Inventor: BOUCKE EDDY ALBERIC
IPC: E04F15/02
Filed: 2018-04-26
Granted: 2021-07-29
Abstract: FIELD: building.SUBSTANCE: invention relates to the field of building, particularly, to floor panels. The panel is comprised of at least one first connecting part and at least one second elastic connecting part. The first connecting part comprises a ridge and a recess formed between the ridge and the end, configured to receive at least a part of the ridge of the second connecting part of the adjoining panel, wherein the ridge and the recess are directed upward. The second connecting part comprises a ridge and a recess configured to receive at least a part of the upwardly directed ridge of the first connecting part of the adjoining panel, wherein the ridge and the recess are directed downward. The second connecting part comprises an elastic upper bridge part containing at least one elongated groove, facilitating deformation thereof.EFFECT: operational reliability of the panels.15 cl, 5 dwg
Patent RU-2750932-C2 (RU)
Title: Closing device
Inventor: VAN DER MOLEN PETER JAN
IPC: B65D75/58
Filed: 2018-04-19
Granted: 2021-07-06
Abstract: FIELD: packaging. 
     SUBSTANCE: invention relates to a closing device and to a container equipped with a closing device. The closing device contains pouring element (1) having a case (11) of pouring element with sealing part and tubular neck (13). The device additionally contains rotating plastic cap (2), which is made with the possibility of manual rotation from the closed position in the direction of opening. The cap has upper wall (21) and skirt hanging down (22) and has two diametrically opposite wing elements (24), which are molded from plastic as a whole and extend in a vertical plane outwards from the skirt in a lateral direction along the length of the wing element. Upper part (24b) of each of the two wing elements contains at least one upper projection (25) extending from base part (24a) along the height of the upper part and laterally along the length of the wing element to the length of the upper projection. The upper projection in the top view of the cap extends substantially in the direction of opening the cap and/or in the direction opposite to the direction of opening the cap, so that in the top view of the cap, the upper part of each of the two wing elements extends along the length of the wing element behind or outwards from the base part of the wing element in the direction corresponding to or opposite to the direction of opening, so that along the length of each upper projection in the section in the vertical plane in the direction of opening, the surface area of this at least one upper projection contributes at least the same contribution to the inertia moment as the surface area of the base part.  
     EFFECT: technical result is ensuring the possibility of reducing the amount of material forming the closing device. 
     15 cl, 9 dwg
Patent UA-71013-C2 (UA)
Title: iphosphate salt of derivatives OF 4''-SUBSTITUTED-9-DEOXO -9А-А3А-9А-HOMOERYTHROTROMYCIN AND PHARMACEUTICAL COMPOSITION THEREOF
IPC: A61P31/04
Filed: 2000-06-13
Abstract: This invention relates to a novel crystalline diphosphate salt of (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[(2,6-dideoxy-3-C-methyl-3-O-methyl-4-C- [(propylamino)methyl]--ribo-hexopryanosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)--D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentade-can-15-one that is useful as an antibacterial and antiprotozoal agent in mammals. This invention also relates to pharmaceutical compositions containing me free base of the diphosphate salt and the methods of treating bacterial and protozoal infections in mammals by administering the free base of the diphosphate to mammals requiring such treatment. The free base of the diphosphate salt of the present invention possesses potent activity against various bacterial and protozoal infections when given by parenteral application to mammals.
Patent UA-75299-C2 (UA)
Title: Method for producing an additional zonal image of a polyzonal digital aerospace picture
Inventor: MOSOV SERHII PETROVYCH
IPC: G06K9/46
Filed: 2005-03-28
Abstract: The proposed method for producing an additional zonal image of a polyzonal digital aerospace picture is distinctive by determining the spectral sensitivity of each existing channel for generating the zonal image, using the data so obtained for determining the required spectral sensitivity of the additional zonal image, and determining signals for generating the image elements. The advantage of the proposed method is enhanced quality in producing additional zonal images.
Patent UA-81036-C2 (UA)
Title: Intermediate for the preparation of therapeutically active imidazopyridines
Inventor: MUELLER BERND
IPC: C07D471/14
Filed: 2004-05-13
Abstract: The invention relates to the 1,5-naphthalene disulfonic acid addition salt of the compound of the formula (I), the compound according to the invention is a valuable intermediate for the preparation of therapeutically active compounds. (I)
Patent UA-83163-C2 (UA)
Title: Unit for transporting and cleaning tuberous roots
Inventor: BULHAKOV VOLODYMYR MYKHAILOVYCH
IPC: A01D33/08
Filed: 2007-06-12
Abstract: A unit for transporting and cleaning tuberous roots consists of a main frame, a feed conveyer, a baffle brush, a heap cleaner, arranged in series, and of an unloading conveyer. Inside a driving hollow cone, arranged vertically and forwarded downwards by vertex thereof, a divider is mounted as the one arranged as a console above the main driving shaft with a flange at the end, whereon an additional shaft with a flange, between which inclined and horizontal rods are arranged in cylindrical hinges, is disposed movably in the axial direction. In doing so the additional shaft is kinematically connected to a driving mechanism of oscillatory movement in the direction of longitudinal axis, and between the flanges of the main and additional shafts a compression spring is arranged.
Patent UA-84245-C2 (UA)
Title: Sour slag-forming mix for out-of-furnace treatment of steel
Inventor: PRAKHNIN VIACHESLAV LEONIDOVYCH
IPC: C21C5/06
Filed: 2007-12-10
Abstract: The invention relates to ferrous metallurgy, namely to sour slag-forming mix for out-of-furnace treatment of steel. A mix contains, w/w: skin of waste welded flux AH-60 or its analogues – 60-80, agglomerate screening – 10-15, fluor spar – 5-10 and silicate clay – other. The invention provides for high degree of purification of metal from oxidizing nonmetallics, low destructive action on sour lining of ladles.
Patent UA-96617-C2 (UA)
Title: Light emitting device for special purposes
Inventor: DZHUZHA OLEKSANDR MYKOLAIOVYCH
IPC: F21L21/00
Filed: 2009-07-30
Abstract: The invention relates to special means and can be used at protection of public order, at arrest of a person that has made a misdeed and as individual means of self-defense. A light-emitting device for special purposes includes light-emitting diodes of white and yellow color, switch of first mode, knob of second mode, switch of third mode, former-controller of voltage of first mode, voltage former of second mode, voltage former of thirds mode, light-emitting diode of blue color, light-emitting diode of red color and light-emitting diode of white color.
Patent UA-92292-C2 (UA)
Title: Process to physically deter fouling from a substrate in an aquatic fouling environment by means of antifouling coating composition based on curable polyorganosiloxane polyoxyalkylene copolymers
Inventor: WILLIAMS DAVID NEIL
IPC: C09D5/16
Filed: 2008-04-28
Abstract: A process to physically deter fouling from a substrate in an aquatic fouling environment, which process comprises forming on the substrate, before exposure to the said environment, a coating composition comprising (i) a curable polyorganosiloxane polyoxyalkylene block copolymer having at least two reactive groups X situated on the copolymer chain and (ii) an organosilicon crosslinking agent and/or a catalyst.
Patent UA-96856-C2 (UA)
Title: lock device and method for opening lock device
Inventor: BEHRENS HOLGER
IPC: B01J3/03
Filed: 2008-10-11
Abstract: The invention relates to a lock device (10, 10') having at least one individual lock (11) for the insertion of strip material (2). In order to be able to maintain or repair the lock device, particularly the individual locks thereof, without needing to remove strip material (2) from the lock device, the invention proposes that the individual lock be made of at least one first and one second part, wherein the two parts are connected to one another via a releasable connection in order to open and close the individual lock, and for at least one device (24, 25) to be provided for moving or displacing the first and second part of the individual lock relative to one another in or opposite the transport direction of the strip material (2) when the connection is open.
Patent UA-101974-C2 (UA)
Title: Method and apparatus for maintaining speech audibility in multi-channel audio with minimal impact on surround experience
Inventor: MUESCH HANNES
IPC: G10L21/00
Filed: 2009-04-17
Abstract: In one embodiment the present invention includes a method of improving audibility of speech in a multi-channel audio signal. The method includes comparing a first characteristic and a second characteristic of the multi-channel audio signal to generate an attenuation factor. The first characteristic corresponds to a first channel of the multi-channel audio signal that contaias speech and non-speech audio, and the second characteristic corresponds to a second channel of the multi-channel audio signal that contains predominantly non-speech audio. The method further includes adjusting the attenuation factor according to a speech likelihood value to generate an adjusted attenuation factor. The method further includes attenuating the second channel using the adjusted attenuation factor.
Patent UA-99042-C2 (UA)
Title: Process for the preparation of lipophilic complex of antimicrobic action
Inventor: HARIACHA OLHA VOLODYMYRIVNA
IPC: A61P31/04
Filed: 2011-02-22
Abstract: A process for the preparation of lipophilic complex of antimicrobic action consists in multiple extraction of plant raw material with organic solvent followed by evaporation up to extragent removal. Yellow bedstraw herb (Galium verum L.) is used as a raw material, the extraction is carried out with chloroform at general ration of raw material:extragent as 1:(10-12) up to solvent decolouring, at a permanently maintained temperature at 55-60° C with recirculation of of the extragent in closed cycle for 28-32 hours.
Patent UA-106592-C2 (UA)
Title: Кристалічна форма 2-тіазоліл-4-хінолінілоксипохідного, активного інгібітора hcv
IPC: A61K31/4709
Filed: 2009-09-14
Abstract: У заявці описані нові кристалічні форми сполуки (1) та її натрієвої солі й способи їх одержання, фармацевтичні композиції, що містять описані форми, та їх застосування для лікування вірусної інфекції гепатиту С (HCV):(1).
Patent UA-103075-C2 (UA)
Title: Prof. v.kondratov analog-to-digital converter
Inventor: KONDRATOV VLADYSLAV TYMOFIIOVYCH
IPC: H03M1/50
Filed: 2011-09-23
Abstract: An analogue-to-digital converter relates to computing and measuring engineering, specifically to parallel, series or parallel/series digital-to-analog converters of directional analog values: voltages, currents, flows, forces, pressure etc. to digital code. The convertor comprises an interface and a base analog-to-digital converter which implements a parallel, series or parallel/series conversion method ing from the known methods by introduction of an automatic switching unit, an adder, a reference source, a keyboard and a microcontroller, whose digital outputs are outputs of the analogue-to-digital converter. The proposed analogue-to-digital converter provides automatic excluding systematic errors at voltage analogue-to-digital conversion, in case of multiple conversions and statistical analysis of intermediate results according to a priori determined equation of digital values decreases a random component of error.
Patent UA-106983-C2 (UA)
Title: IMPROVED TEMPORARY bridge
Inventor: DESCHAMPS GEORGES-PAUL
IPC: E01D15/00
Filed: 2010-03-15
Abstract: The invention relates to a temporary bridge including two spans (1, 2), each comprising at least three bridge elements (3-5) to be stacked when the bridge is in a first so-called non-deployed position. Said bridge elements (3-5) are pivotably connected to one another, wherein two consecutive bridge elements (3-5) are connected to one another by at least two linking arms (7-9, 12, 13) mounted on the same side edge of said bridge elements (3-5). According to the invention, two consecutive linking arms (7-9, 12, 13) form a regular parallelogram with the two consecutive bridge elements connected by said arms, which can be deformed such that the movement of one bridge element relative to a bridge element immediately below in the stack of a span (1, 2) in said non-deployed position of said bridge causes the circular translation of said bridge element relative to said bridge element of said span immediately below. For at least one of said spans, at least one of the linking arms (8, 12, 13) is shared by three consecutive bridge elements. The bridge comprises a means for moving each bridge element (3, 4) stacked on another bridge element (4, 5) in the first position between said first position and a second position, referred to as a deployed position, in which the bridge elements are coupled together to form the bridge.
Patent UA-104899-C2 (UA)
Title: Preserving agent for water and feed
IPC: A23K20/195
Filed: 2010-08-03
Abstract: Antimicrobial compositions containing buffered propionic or acetic acid mixed with pelargonic acid.
Patent UA-105317-C2 (UA)
Title: Machine for production of pipes made of reinforced plastics
Inventor: DANILTSEV VOLODYMYR HRYHOROVYCH
IPC: B29C53/00
Filed: 2013-04-01
Abstract: The invention relates to the field of chemical engineering and can be used in particular for production of pipes made of polymeric composite materials including fiberglass pipes by continuous winding method. The purpose of the invention is to improve the machine for production of pipes made of reinforced plastics, in which due to use of such components as a main drive of a mandrel shaft, which provides basic rate of descent of a finished pipe, a mechanism of stacking protective tape and its actuator, an actuator of the mechanism for movement of a manufactured pipe, a heater of binder and cross reinforcing material, length sensors of individual sections of the manufactured pipe and a sensor for length control of the finished pipe, a receiving trolley with roller conveyors and a rail track, use of autonomous gear-motors as drives of the mechanisms for stacking the protective tape, a transfer mechanism of a manufactured pipe and a stacker of the longitudinal reinforcing material, the implementation in the form of a single unit of polymerization chambers and their location at the end of the mandrel before the descent of the finished portion of the pipe from the mandrel thus achieving the reduction of the number of substandard products in relation to the finished product at the expense of the machine design with broader functionality.
Patent UA-108271-C2 (UA)
IPC: C02F1/68
Filed: 2011-11-10
Abstract: Заявлений винахід належить до камери (8) витримування. Зокрема, винахід належить до камери (8) витримування, що забезпечує підвищення ефективності дії біоциду при очищенні води. Іншим аспектом заявленого винаходу є введення камери (8) витримування в обладнання для очищення води, зокрема в обладнання для очищення води з подачею води самопливом, що функціонують без використання електроенергії й нагнітання води, однак камера витримування, згідно з винаходом, може бути введена в обладнання для очищення води, що функціонують із використанням електроенергії й нагнітання води. Установлено, що камера витримування, обладнана простим виконавчим обладнанням, складається із завантажувальної ванни (5), плунжера й пружного елемента (7), що діють як механізм автоматичного керування процесом очищення, забезпечує достатню тривалість обробки води з використанням біоциду.
Patent UA-105468-C2 (UA)
Title: Multichannel meter of time intervals in pulse series
Inventor: LABINSKYI KOSTIANTYN MYKOLAIOVYCH
IPC: G04F10/00
Filed: 2013-07-08
Abstract: A multichannel meter of time intervals in pulse series comprises information reception RS flip-flops, time counter which inverting input and R reset input are connected to the bus of time pulses and to the bus of reference pulses, correspondingly, second counter which inverting input is connected to the bus of clock pulses, and Q-outputs of information reception flip-flops are connected to A address inputs of multiplexor which data D-inputs are connected to Q-outputs of corresponding information reception RS flip-flops which S-inputs are connected to corresponding input buses, RS flip-flop which S-input is connected to the bus of reference pulses. The meter additionally comprises n DC flip-flops and n EXCLUSIVE OR gates, buffer register, wherein C-inputs of DC flip-flops are connected to the bus of reference pulses, and D-inputs are connected to corresponding input buses and to first inputs of EXCLUSIVE OR gates, to which second inputs Q data outputs of DC flip-flops are connected. Data outputs of EXCLUSIVE OR gates are connected to S-inputs of information reception RS flip-flops to which R-inputs the bus of reference pulses is connected. Q-outputs of T-bit time counter and Q-outputs of the information reception RS flip-flops are connected to data D-inputs of the buffer register. C-input of the buffer register is connected to gating line of output data bus and to multiplexor output through AND gate, overflow output of P+T-bit time counter and Q-outputs of the buffer register are accessible for connection of microcomputer.
Patent UA-108776-C2 (UA)
Title: Method for diagnosis of local restrictions of reserves in tortuos coronary arteries in patients with coronary heart disease and coronary syndrome x
Inventor: SEBOV DENIS MYKHAILOVYCH
IPC: A61B5/05
Filed: 2013-07-22
Abstract: The invention relates to medicine, namely to cardiology, radiology and cardiovascular surgery, as well as fluid mechanics and can be applied for diagnosis of hemodynamic significance of coronary artery tortuosity in coronary heart disease (CHD ).
Patent UA-107768-C2 (UA)
Title: Вертикальний ендопротез сегмента хребта
Inventor: KORZH MYKOLA OLEKSIIOVYCH
IPC: A61F2/44
Filed: 2014-01-27
Abstract: Використання: при хірургічному лікуванні захворювань та ушкоджень хребта, зокрема його шийного відділу, під час виконання переднього спондилодезу з використанням штучних імплантатів, зокрема порожнистих сітчастих ендопротезів. Вертикальний ендопротез сегмента хребта являє собою центральний порожнистий шток з різноспрямованою від його центру різьбою, на яку нагвинчуються півкорпуси з зубцями на зовнішніх торцях та оснащених Г-подібними пластинами з отворами під гвинти, а також шток та півкорпуси мають наскрізні бічні отвори однакового діаметра, розташовані ярусами. Щонайменше один бічний отвір нижнього ярусу кожного півкорпусу має наскрізний проріз, який з'єднує вказаний отвір з торцем півкорпусу. Отвір з прорізом просторово орієнтований до того ж боку, з якого на півкорпусі розташована Г-подібна пластина. Технічні переваги: можливість максимально змінювати загальну довжину ендопротеза залежно від індивідуальних особливостей пацієнта; спрощення фіксації півкорпусів відносно штока; спрощення конструкції півкорпусів.
Patent UA-114555-C2 (UA)
Title: Спосіб одержання гідрохлориду 1-(трифлуорометил)циклопропанаміну
IPC: C07C211/62
Filed: 2015-10-09
Abstract: Винахід належить до органічної хімії, а саме до нового способу одержання гідрохлориду 1-(трифлуорометил)циклопропанаміну формули (1): EMBED ISISServer . В основі винаходу лежить препаративно простий і зручний в синтетичному плані двостадійний метод отримання цільової сполуки реакцією комерційно доступної 1-(трифлуороацетил)аміноциклопропанкарбонової кислоти з тетрафлуоридом сірки з подальшим зняттям захисної трифлуороацетильної групи з атома азоту проміжного продукту нагріванням у метанолі, насиченому хлоридом водню. Вихід цільової сполуки становить 65,3 %.
Patent UA-113360-C2 (UA)
IPC: A61L27/30
Filed: 2015-12-07
Abstract: Винахід належить до області медичної техніки і може бути використаний при виготовленні імплантатів для стоматології, травматології, ортопедії, судинної хірургії, різних видів пластичної хірургії. Імплантат містить основу, покриту оксидною плівкою, поверхня якої в зоні контакту з м'якими тканинами містить борозенки, нанесені лазером. Розміри борозенок становлять 5-300 нм, борозенки розташовані в заданому напрямку залежно від анатомічної локалізації і функціонального призначення імплантата з інтервалом 5-400 нм. Технічний результат: поліпшення адгезії і наступної інтеграції клітинних елементів м'яких тканин у структуру оксидної плівки, за рахунок чого досягається стійке і міцне, незмінне під впливом функціонального навантаження, з'єднання м'яких тканин з поверхнею імплантата, що, у свою чергу, дозволяє розширити функціональні можливості імплантата, що заявляється.
Patent UA-116484-C2 (UA)
Title: Antibacterial 2h-indazole derivatives
Inventor: GAUVIN JEAN-CHRISTOPHE
IPC: C07D413/10
Filed: 2014-12-09
Abstract: The invention relates to antibacterial compounds of formula (I) wherein R1 is H or halogen; R2 is alkynyloxy or the group M; R3 is H or halogen; M is one of the groups (A, В, C, D) wherein A is a bond, CH2CH2, CH=CH or C(C and R1A, R2A, R3A, R1B and R1C are as defined in claim 1; and salts thereof. EMBED ISISServer I A B EMBED ISISServer EMBED ISISServer C D EMBED ISISServer EMBED ISISServer