baber/WOPTO huggingface dataset:
Patent CA-2559848-A1 (CA)
Inventor: BENZ JOERG
IPC: G01N23/20
Filed: 2006-08-25
Abstract: The present invention provides crystals of carnitine palmitoyltransferase (CPT) and co-crystals of CPT with an inhibitor compounds that allow screening for novel inhibitors of CPT-2 by determining the structure of co-crystals based on the coordinates of the crystals disclosed herein.
Patent CA-2559896-A1 (CA)
Title: Conteneur ayant un anneau de prehension et poignee optionnelle
Inventor: SEMERSKY FRANK E
IPC: B65D23/10
Filed: 2005-02-25
Abstract: L'invention concerne un conteneur plastique comprenant une paroi latérale cylindrique élastiquement déformable et un anneau plastique en contact et intégré dans la surface externe de la paroi latérale. L'anneau plastique peut éventuellement comporter une poignée fixée à l'anneau. L'anneau plastique a une circonférence interne inférieure à la circonférence de la paroi latérale du conteneur plastique de telle manière que la surface externe de la paroi latérale du conteneur soit concave au niveau de son point de contact avec l'anneau plastique, fournissant ainsi une poignée dans la paroi latérale du contenant plastique.
Patent CA-2560166-A1 (CA)
Inventor: SCHWARTZ THUE
IPC: A61K38/17
Filed: 2005-03-17
Abstract: La présente invention concerne des agonistes du récepteur Y, qui sont sélectifs des récepteurs Y2 et Y4 par rapport au récepteur Y1, et qui sont utiles pour traiter, par exemple, l'obésité. Ces agonistes sont (a) des peptides à repli PP ou des analogues de peptides à repli PP qui comprennent: (i) une séquence d'acides aminés à reconnaissance de récepteur Y à terminal C, représentée par la formule -X-Thr-Arg-X?3¿-Arg-Tyr-C(=0)NR?1¿R?2¿ dans laquelle R?1¿ et R?2¿ sont indépendamment hydrogène ou alkyle en C¿1?-C¿6?; X est Val, lle, Leu ou Ala, et X?3¿ est Gln ou Asn, ou une variante à substitution conservatrice dans laquelle Thr est remplacé par His ou Asn et/ou Tyr est remplacé par Trp ou Phe, et/ou Arg est remplacé par Lys; et (ii) une séquence d'acides aminés à reconnaissance de récepteur Y à terminal N, représentée par la formule H¿2?N-X?1¿-Pro-X?2¿-(Glu ou Asp)- dans laquelle X?1¿ n'est pas présent ou est un radical acide aminé, et X?2¿ est Leu ou Ser ou des substitutions conservatrices de Leu ou Ser; ou lesdits agonistes comprennent (b) une séquence d'acides aminés à reconnaissance de récepteur Y à terminal C telle que définie dans (i) décrit ci-dessus, ladite séquence de reconnaissance de récepteur Y étant fusionnée à un domaine de séquence d'acides aminés amphiphile comprenant au moins une spire d'hélice alpha adjacente au terminal N de ladite séquence hexapeptidique, ladite spire étant contrainte dans une configuration hélicoïdale par une liaison covalente intramoléculaire, et éventuellement une séquence à terminal N qui débute par une séquence d'acides aminés à reconnaissance de récepteur Y telle que définie dans (ii) décrit ci-dessus.
Patent CA-2560624-A1 (CA)
Title: High performance business framework and associated analysis and diagnostic tools and processes
Inventor: MANN BRIAN
IPC: G06Q10/06
Filed: 2006-09-22
Abstract: Disclosed is a high performance business framework and related tools and processes for describing how known high performance businesses derive performance contributions from three building blocks. The present invention provides methods and tools for researching, measuring and quantifying these three building blocks to enable assessments to be made of various companies in various industries and methods and tools for enabling these various companies to identify and adopt solutions that enable them to model themselves after high performers.
Patent CA-2560832-A1 (CA)
Title: Canopy cover having a meshed portion
Inventor: MEYER TED H
IPC: E04H15/54
Filed: 2005-03-24
Abstract: A canopy system including a canopy frame and a canopy cover supported by the canopy frame. The canopy cover includes an inner solid portion, an outer sol id portion, and a meshed portion disposed between the inner and outer solid portions and disposed proximately to an outer periphery of the canopy cover.
Patent CA-2565262-A1 (CA)
Title: Nutritional formulations
Inventor: KIRSCHNER MITCHELL I
IPC: A61K9/64
Filed: 2005-05-11
Abstract: This invention relates to novel nutritional supplements comprising essential fatty acids and iron, as well as methods related thereto.
Patent CA-2565369-A1 (CA)
Inventor: BENINI BRYON E
IPC: F41B11/00
Filed: 2005-05-25
Abstract: A novel and unique pneumatic paintball marker having a variety of novel features, the first being an on/off compressed air control valve, positioned at the front of the marker below the barrel and adjacent to an in-line pressure regulator. Major innovations have been made in reducing the size and weight of the body of the marker, along with the construction of a new bolt assembly consisting of just four components and only moving part. An anti-chop eye electronic system insures that the paintballs are in proper position, and rubber ball detents are optionally added to hold the paintballs in place prior to firing the marker, so that the paintballs will not roll out the barrel.
Patent CA-2565568-A1 (CA)
Title: Pyrimidines as plk inhibitors
Inventor: REISER ULRICH
IPC: C07D239/48
Filed: 2005-05-13
Abstract: The present invention comprises compounds of general formula (1) (see formula 1) wherein A, X, Y, Z, R a, R b, R c, R1, R2 and R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or anomalous cell proliferation, and the use thereof for preparing a pharmaceutical composition with the above-mentioned properties.
Patent CA-2566351-A1 (CA)
Inventor: CEDERFERM JOSEPH
IPC: B05B/
Filed: 2005-05-17
Abstract: A shower or car-wash is provided with a heat-exchanger element of thin sheet metal mounted under or in the floor to pre-heat incoming cold water using heat re-covered from the spent sprayed water. The heat exchanger element (15) has a rec-tangle-wave shaped cross section thereby providing greater heat transfer area and being able to withstand heavy vertical loads. The vertical portions (13) of the rec-tangle wave may advantageously be provided with vertical reinforcing ribs in the form of depressions (6a, 6b) stamped in the metal.
Patent CA-2566359-A1 (CA)
Inventor: CARDARELLA L JAMES JR
IPC: F01D11/20
Filed: 2005-05-13
Abstract: In one embodiment, a low or high pressure turbine case (204) is machined on its outside surface to form circumferential notches (302). The notches may coincide with internal locations of seals (210) for the blades (208), or with "hot spots" that have been identified, for example. A stiffener ring (304) may be shrunk with an interference fit into each notch (302) through inducing temperature differentials between the ring and the case. The radially compressive circumferential force exerted by each ring can inhibit the low or high pressure turbine case from expanding as much as it would otherwise. In some applications, a stiffener ring can improve blade tip clearance or counterbalance "hot spots", stiffen the case, improve case cooling, or other benefits, depending upon the particular application. In one embodiment, notches may be avoided. In an alternate embodiment, C-rings, or multiple segmented rings, may be coupled together by hydraulic, electrical, or other means and actuated by a controller to exert adjustable radially compressive circumferential force. Other embodiments are described and claimed.
Patent CA-2567187-A1 (CA)
Inventor: DEHMESHKI JAMSHID
IPC: G06V10/28
Filed: 2005-05-13
Abstract: A method of detecting the extent of a lung nodule in a scan image comprises fine segmenting (14) a region around the nodule into foreground and background, filling holes within foreground areas (16), region growing the foreground (18) to identify an initial region of interest, determining a mask (20) by enlarging the initial region to contain background and to exclude other foreground regions, determining a spatial map (26) of connectivity within the mask to a point within the initial region, region growing (28) within the mask and determining the maximum edge contrast (30) during region growing. The region of maximum edge contrast identifies the extent of the nodule (32). The position of the nodule may a seed point identified by the user (12). Most preferably, an optimum seed point is determined by iterative determination of seed points (22, 24) so that the determined extent of the nodule is substantially independent of the precise location of the seed point identified by the user.
Patent CA-2567547-A1 (CA)
Title: Method for enhancing production of isoprenoid compounds
Inventor: KEASLING JAY D
IPC: A61K48/00
Filed: 2005-05-20
Abstract: The present invention provides methods of producing an isoprenoid or an isoprenoid precursor in a genetically modified host cell. The methods generally involve modulating the level of hydroxymethylglutaryl-CoA (HMG-CoA) in the cell, such that the level of HMG-CoA is not toxic to the cell and/or does not substantially inhibit cell growth, but is maintained at a level that provides for high-level production of mevalonate, IPP, and other downstream products of an isoprenoid or isoprenoid pathway, e.g., polyprenyl diphosphates and isoprenoid compounds. The present invention further provides genetically modified host cells that are suitable for use in a subj ect method. The present invention further provides recombinant nucleic acid constructs for use in generating a subject genetically modified host cell, including recombinant nucleic acid constructs comprising nucleotide sequences encoding one or more mevalonate pathway enzymes, and recombinant vectors (e.g., recombinant expression vectors) comprising same. The present invention further provides methods for identifying nucleic acids that encode HMG-CoA reductase (HMGR) variants that provide for relief of HMG-CoA accumulation-induced toxicity. The present invention further provides methods for identifying agents that reduce intracellular accumulation of HMG-CoA.
Patent CA-2568710-A1 (CA)
Title: Method for producing flexible, stretchable, and implantable high-density microelectrode arrays
Inventor: KRULEVITCH PETER
IPC: A61B5/296
Filed: 2006-11-23
Abstract: A high-density microelectrode array that is flexible and stretchable and can also be implanted within living tissue is provided. The microelectrode array includes at least first and second implantable and biocompatible polymeric layers in which a plurality of patterned conductive features, including metallic contact pads, metallic traces and metallic electrodes are sandwiched therebetween. Each metallic trace is located between a metallic contact pad and a metallic electrode and has substantially rounded corners and a zigzag pattern. The latter features are provided using stent technology. The present invention also provides a method of fabricating such a flexible, stretchable, and implantable microelectrode arrays which combined micromaching technology and stent technology as well as an implantable medical device that includes the inventive microelectrode array.
Patent CA-2568842-A1 (CA)
Title: Uwb location system for rescuing avalanche victims
Inventor: DANIELE NORBERT
IPC: G01S13/88
Filed: 2005-06-07
Abstract: The invention relates to a system for locating an ULB transmitter (120, 130) without a preliminary fixed reference with the aid of at least one assembly of at least three ULB search transceivers (20, 22, 24) comprising the first, second and third transceiver. The inventive method consists a) in synchronising said three ULB search transceivers disposed in three different points and in evaluating the relative position thereof, b) in receiving signals (121, 131) transmitted by a locatable transmitter by said three transceivers, c) in calculating the relative position of the locatable transmitter with respect to the three search transceivers according to the propagation time of signals transmitted by a locatable transceiver (120, 130) towards said three search transceivers.
Patent CA-2569777-A1 (CA)
Title: Method and apparatus for the drying of the printing plates for flexography
Inventor: DE CARIA RICCARDO
IPC: G03F7/16
Filed: 2005-06-08
Abstract: The present invention provides for an apparatus for the drying step of the printing plates for flexography, so as to let a solvent present inside the plates to evaporate, comprising a base element (9, 25) for carrying the printing plates (8, 26) and a lighting system (1, 23) above the printing for heating the printing plates by irradiation of visible light wavelengths.
Patent CA-2575547-A1 (CA)
Title: Substituted quinobenzoxazine analogs and methods of using thereof
Inventor: SCHWAEBE MICHAEL
IPC: A61P31/04
Filed: 2005-07-29
Abstract: The present invention relates to quinobenzoxazines analogs having the general formula: (1) or (2) and pharmaceutically acceptable salts, esters and prodrugs thereof; wherein V, A, X, Z, W, U and R5 are substituents. The present invention also relates to methods for using such compounds, such as in screening and for inducing apoptosis.
Patent CA-2579462-A1 (CA)
Inventor: PRINS MARTY L
IPC: A47B53/00
Filed: 2007-02-22
Abstract: An organization system according to the present invention generally includes a plurality of reconfigurable carts that can be positioned in the storage site in a generally side-by-side configuration. At least one of the carts can be movable from the storage site to the remote location independent of the other cart. The carts can include one or more selectively positionable partitions, such that the storage space is adjustably dividable into a number of defined reconfigurable modules for separable storage of the equipment.
Patent CA-2581637-A1 (CA)
Title: Liquid measuring vessel
Inventor: CHAN DAVID
IPC: G01F19/00
Filed: 2007-03-14
Abstract: The present invention relates to a liquid measuring vessel having a removable volume indicating clip.
Patent CA-2582620-A1 (CA)
Inventor: ANDERSON ROBERT O
IPC: B60Q11/00
Filed: 2007-03-22
Abstract: A system and method for associating a vehicle and vehicle trailer is described.  The system comprises one or more sensors that transmit information wirelessly to a tractor display unit. The tractor display unit determines whether the sensor is associated with a trailer to which it is connected and filters out messages from sensors that are not associated with its trailer. To determine which sensors are associated with its trailer, a processor in the tractor display unit synchronizes the reception of sensor messages with the reception of a synchronizing signal, such as a signal generated by operating an auxiliary power system, turn signal, or brake.
Patent CA-2584224-A1 (CA)
Inventor: CHU ZHI LIANG
IPC: A61K49/00
Filed: 2005-11-01
Abstract: The present invention relates to a method for identifying a glycemic stabilizing compound by: a) contacting a candidate compound with GPR41, and b) determining whether GPR41 functionality is modulated, where a modulation in GPR41 functionality is indicative of the candidate compound being a glycemic stabilizing compound. In addition, the invention relates to a method for identifying a glycemic stabilizing compound, comprising: a) contacting a candidate compound with GPR41, and b) determining whether GPR41 functionality is increased, wherein an increase in GPR41 functionality is indicative of the candidate compound being a glycemic stabilizing compound. Further, the invention relates to a method for identifying a glycemic stabilizing compound, comprising: a) contacting a candidate compound with GPR41, and b) determining whether GPR41 functionality is decreased, wherein a decrease in GPR41 functionality is indicative of the candidate compound being a glycemic stabilizing compound.
Patent CA-2586734-A1 (CA)
Inventor: PECK LAWRENCE R
IPC: B65B13/18
Filed: 2007-04-27
Abstract: A polymeric batten for supporting an associated load includes a main body having a base wall having a pair of opposing, spaced apart upstanding side walls extending upwardly from the base wall and a pair of opposing, spaced apart legs extending downwardly from the base wall. The legs are spaced from one another a predetermined distance and the side walls are spaced from one another a predetermined distance. The upstanding side walls and base wall define a generally U-shaped profile and the legs and base wall define a generally inverted U-shaped profile that defines a strap receiving region configured for receiving an associated strap material disposed around the load and the batten. A load strapping and supporting system is also disclosed.
Patent CA-2587349-A1 (CA)
Inventor: WARDLEY MICHAEL
IPC: E21B33/16
Filed: 2005-11-14
Abstract: Apparatus for use above and below a restriction (18) in a well bore and a method of operation is described. The apparatus comprises an upper element, such as a wiper (12) , operable in the well bore above the restriction and a lower element, which may be a lower wiper (14) , operable in the well bore below the restriction. A drop ball (38) sized to pass through the restriction is released from the upper element and thereby passes through the restriction to operate the lower element. In one embodiment, the apparatus is incorporated into a running tool, which may be used to hang liners by dimple forming.
Patent CA-2588578-A1 (CA)
Title: Procede de fixation d'un arbre de transmission flexible dans un inverseur de poussee et un tel inverseur de poussee
Inventor: MIRABAUD JOACHIM
IPC: F02K1/76
Filed: 2005-12-15
Abstract: II est présenté un procédé de fixation d'un arbre de transmission (9) flexible dans un cadre avant (1) d'un inverseur de poussée, ledit cadre avant étant réalisé à l'aide de deux éléments (2, 3) semi-circulaires entrouverts, ce procédé comprenant une étape au cours de laquelle une première extrémité (19) dudit arbre est rattachée à un système d~entrainement (7) fixé dans un élément (2) du cadre avant, caractérisé en ce qu'il comprend les étapes visant à :  positionner au moins un manchon de fixation (10) autour de l'arbre, -solidariser au moins un support de fixation (14) à l'inverseur, - raccorder la seconde extrémité (20) de l'arbre à un système d~entrainement (8) fixé dans l'autre élément (3) du cadre avant, - introduire en force chaque manchon de fixation dans un logement présenté par le support de fixation associé afin de maintenir l'arbre dans une position prédéterminée . De plus un inverseur de poussée utilisé dans l'aéronautique possédant un manchon de fixation (10) positionné autour de l'arbre de transmission est aussi présenté.
Patent CA-2593529-A1 (CA)
Inventor: BERENYI ANDREW
IPC: B62D35/00
Filed: 2005-12-05
Abstract: A deflector (10) for mounting at a rear of a vehicle (12), the deflector (10) being arranged, in operation, to project sidewards of the vehicle (12) as one or more ducts (22, 26, 28) to direct air from along a side (14) of the vehicle (12) through a region (30) behind the vehicle (12) and allow continuous airflow through the region (30) and behind the vehicle (12) to thereby reduce vacuum effect, the deflector (10) being adapted to move to a retracted condition, when not in use, to allow unobstructed opening of a rear door of the vehicle (12). Similarly a method of reducing drag of a moving vehicle by mounting of a deflector to the vehicle is disclosed.
Patent CA-2594146-A1 (CA)
Title: Systeme de ventilation de paroi de chambre de combustion
Inventor: LOCATELLI DAVID
IPC: F23R3/42
Filed: 2007-07-16
Abstract: Système de ventilation de paroi de chambre de combustion dans une turbomachine comprenant un compresseur centrifuge alimentant par un diffuseur une chambre de combustion, ce système comportant un caisson annulaire agencé radialement entre la chambre de combustion et un flasque aval du diffuseur et qui comporte une paroi radialement externe pour le guidage d'un flux d'air sortant du diffuseur, et une paroi radialement interne délimitant avec le flasque du diffuseur une voie de passage d'air sortant du diffuseur.
Patent CA-2594231-A1 (CA)
Title: Treating a tumor or the like with electric fields at different orientations
Inventor: PALTI YORAM
IPC: A61N1/32
Filed: 2005-12-27
Abstract: Cells that are in the late anaphase or telophase stages of cell division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like tumor cells, but does not harm normal cells that are not dividing. Since the vulnerability of the dividing cells is strongly related to the alignment between the long axis of the dividing cells and the lines of force of the electric field, improved results are obtained when the field is sequentially imposed in different directions. The field may also be rotated through 360~ by applying AC waveforms with different phases to the electrodes.
Patent CA-2595567-A1 (CA)
Inventor: TONCELLI DARIO
IPC: B29C48/76
Filed: 2006-01-26
Abstract: Method for producing articles which are not flat from a mix consisting of granulated inorganic materials and a hardening resin. After being compacted by means of vacuum vibrocompression on a flat forming support, the mix is transferred onto a form (300), the surface (350) of which has the same curvature as the article (100) to be obtained, and is left there until hardening of the mix is achieved. The articles made using this method and able to be used in various industrial and civil applications are also claimed.
Patent CA-2595610-A1 (CA)
Title: Antibodies directed to angiopoietin-2 and uses thereof
Inventor: KEYT BRUCE A
IPC: C07K16/22
Filed: 2005-12-19
Abstract: Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human mon-oclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementary determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobin molecules and monoclonal antibodies.
Patent CA-2598663-A1 (CA)
Title: Layer cutting apparatus
Inventor: BAGGIO LINDA
IPC: B26B3/00
Filed: 2006-02-22
Abstract: A layer cutting apparatus comprising a tray having an interior defined by a bottom and sidewall. A sleeve is at least partially disposed in the interior of the tray and a cutting line is attached to the sleeve. The cutting line is configured to be removed from the sleeve by pulling the line away from the tray at one point of the sidewall.
Patent CA-2602987-A1 (CA)
Inventor: MENGISTU TESFAHUN Y
IPC: B65D5/32
Filed: 2007-09-19
Abstract: A container configured to be selectively moved between a substantially flat position and a deployed position is provided. The container includes a first blank of sheet material for forming side walls of the container, and a second blank of sheet material for forming a bottom wall of the container. The first blank having an interior surface and an opposing exterior surface, a top edge and a bottom edge. The first blank includes a first side panel, a second side panel, a third side panel, a fourth side panel, a fifth side panel, and a sixth side panel wherein each of the side panels are coupled across a fold line. The first blank also includes end flaps extending from the bottom edge of each of the side panels wherein at least two of the end flaps includes a tab joint. The second blank having a plurality of side edges equal to a number of side panels of the first blank, each side edge having a width substantially equal to a width of the side panels of the first blank. The second blank is foldable and is coupled to at least one end flap of the first blank for forming a bottom wall of the container.