baber/WOPTO huggingface dataset:
Patent CA-2881679-A1 (CA)
Inventor: YANCOPOULOS GEORGE D
IPC: C07K16/40
Filed: 2013-08-12
Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind proprotein convertase subtilisin/kexin-9 (PCSK9) with greater affinity at neutral pH than at acidic pH. The antibodies disclosed herein may possess one or more amino acid changes as compared to antibodies that do not exhibit pH-dependent binding properties. For example, the present disclosure includes anti-PCSK9 antibodies which possess one or more histidine substitutions in one or more complementarity determining regions. The antibodies disclosed herein, with pH-dependent binding properties, remain in circulation and exhibit cholesterol lowering activity for prolonged periods of time in animal subjects as compared to anti-PCSK9 antibodies that do not exhibit pH-dependent binding properties. The antibodies disclosed herein are therefore useful for treating diseases and disorders related to elevated HDL cholesterol, wherein the antibodies disclosed herein can be administered to a patient at a lower dose and/or with less frequent dosing as compared to antibodies that do not exhibit pH-dependent binding properties.
Patent CA-2884734-A1 (CA)
Inventor: FOURNIER SEBASTIEN
IPC: B64B1/58
Filed: 2013-09-19
Abstract: An aircraft comprising a hydrogen-containing envelope, a water-collection system for collecting water from the envelope, an electrolyser to convert the water collected using the water-collection system into hydrogen, and a hydrogen- replenishment system for replenishing the envelope with hydrogen generated using the electrolyser. In one embodiment, generated hydrogen is also supplied to a hydrogen-fuelled propulsion system for propulsion of the aircraft.
Patent CA-2885870-A1 (CA)
Inventor: MURISON BRUCE
IPC: F04B17/04
Filed: 2013-09-26
Abstract: A device for use by an individual for sexual pleasure varying in form, i.e. shape, during its use and allowing for the user to select multiple variations of form either discretely or in combination and for these dynamic variations to be controllable simultaneously and interchangeably while being transparent to the normal use of the device, including the ability to insert, withdraw, rotate, and actuate the variable features manually or remotely. According to embodiments of the invention localized and global variations of devices are implemented using fluidics and electromagnetic pumps/valves wherein a fluid is employed such that controlling the pressure of the fluid results in the movement of an element within the device or the expansion/contraction of an element within the device.
Patent CA-2886660-A1 (CA)
Inventor: MCCONNACHIE PETER NAIRN
IPC: B62K11/00
Filed: 2015-03-31
Abstract: Heretofore, neither branded nor generic mobility devices, have provided for anyone to travel with the scooter operator or the wheelchair occupant. In addition mobility scooters and wheelchairs have not been connected together nor travelled tethered together with one operator and one or more companions close behind. My innovative concepts solve those limitations by providing methods of tethering, sharing of both motive battery energy and braking dynamics, provision of supplemental power to extend the operational range of mobility devices as well as providing safety features such as electric disc brakes on wheel chairs and security of equipment by installing battery chargers within the body framework of mobility scooters and wheelchairs as well as providing for supplemental power being supplied from mobility devices in tow..
Patent CA-2887978-A1 (CA)
Title: Removable heater for communication antenna
Inventor: SWAIN RICHARD LAWRENCE
IPC: H05B3/02
Filed: 2013-10-21
Abstract: A heater assembly including a foil heater having at least one slot. The heater assembly includes an insulating plate configured to electrically and thermally insulate the foil heater, the insulating plate having a central opening, at least one first mounting hole and at least one first fastening hole. The heater assembly includes a heat dissipation element configured to conduct heat from the foil heater to an exterior of the heater assembly, the heat dissipation element having at least one second mounting hole and at least one second fastening hole. The foil heater is between the insulating plate and the heat dissipation element. The at least one first mounting hole, the at least one slot and the at least one second mounting hole are aligned. The at least one first fastening hole, the at least one slot and the at least one second fastening hole are aligned.
Patent CA-2891113-A1 (CA)
Inventor: HANNON DAVID
IPC: A61M25/00
Filed: 2013-03-12
Abstract: A urinary catheter has a body and an outer layer surrounding at least a portion of the body. The structure of the body is varied and non-uniform so as to impart a varying flexibility along the length of the catheter. The frame may be injection molded, while the outer layer may be extruded. The frame may also, or alternatively, have selected regions or portions that include planar or spiral cuts or a coiled filament or corrugations or a multifilament braid or weave or mesh to impart a desired flexibility profile. The flexibility profile of a male urinary catheter may include alternating rigid and flexible regions, with proximal and distal rigid regions being configured to be positioned within the bladder and penis, with two flexible regions separated by a rigid region positioned between the penis and bladder when the catheter is deployed within a male urethra.
Patent CA-2892757-A1 (CA)
Title: Colorectal cancer classification with differential prognosis and personalized therapeutic responses
Inventor: SADANANDAM ANGURAJ
IPC: C12Q1/68
Filed: 2013-11-26
Abstract: The present invention relates to gene sets, the expression levels of which are useful for classifying colorectal tumors and predicting disease-free prognosis and response of patients to specific therapies that are either novel or currently available in the clinics for colorectal cancer patients.
Patent CA-2893111-A1 (CA)
Inventor: TAGHIZADEH NOUEI MEHRDAD
IPC: B33Y50/02
Filed: 2015-06-01
Abstract: A 2D/3D Scanner and printer (1) is provided. The system includes an enclosure having a 2D/3D scanner (2) a full color or mono 3D  printer; an embedded controller board with USB/WiFi connection built in, a 64 bit PC with ,multi core processor, a motorized turning table (5), a fully authorized and customized program (online/offline update available), and motorized rail for scanner position control (3).
Patent CA-2893458-A1 (CA)
Title: Poudre haute purete destinee a la projection thermique
Inventor: BILLIERES DOMINIQUE
IPC: C01F17/224
Filed: 2013-11-29
Abstract: Powder of particles, more than 95% by number of said particles exhibiting a circularity greater than or equal to 0.85, wherein said powder contains more than 99.8% of a rare earth oxide and/or of hafnium oxide and/or of yttrium aluminium oxide, as percentage by weight relative to the oxides, and has:  a median particle size D 50 of between 10 and 40 microns and a size dispersion index (D 90 - D 10)/D 50 of less than 3; - a percentage by number of particles having a size less than or equal to 5 ium which is less than 5%; - an apparent-density dispersion index (P < 50 -P)/P of less than 0.2, the cumulative specific volume of the pores which have a radius of less than 1 ium being less than 10% of the apparent volume of the powder, in which the percentiles Dn of the powder are the particle sizes corresponding to the percentages, by number, of n%, on the curve of cumulative distribution of the particle size of the powder, the particle sizes being classified in increasing order, the density P < 50 being the apparent density of the fraction of particles having a size less than or equal to D50, and the density P being the apparent density of the powder.   Poudre de particules, plus de 95% en nombre desdites particules présentant une circularité supérieure ou égale à 0,85, ladite poudre contenant plus de 99,8% d'un oxyde de terre rare et/ou d'oxyde d'hafnium et/ou d'un oxyde d'yttrium-aluminium, en pourcentage par masse sur la base des oxydes, et ayant: -une taille médiane de particule D 50 comprise entre 10 et 40 microns et un indice de dispersion de taille (D 90 -D 10 )/D 50 inférieur à 3; -un pourcentage ennombrede particules ayant une taille inférieure ou égale à 51µm qui est inférieur à 5%; -un indice de dispersion de densité  apparente (P <50 -P)/P inférieur à 0,2, le volume spécifique cumulé des pores ayant un rayon inférieur à 1  métant inférieur 1 à  10% du volume apparent de la poudre, dans laquelle les percentiles D n de la poudre sont les tailles de particule correspondant aux pourcentages, en nombre, de n%, sur la courbe de distribution cumulée de la taille des particules de la poudre, les tailles de particule étant classées par ordre croissant, la densité P <50 étant la densité apparente de la fraction des particules ayant une taille 20 inférieure ou égale à D 50, et la densité P  étant la densité apparente de la poudre.
Patent CA-2895159-A1 (CA)
Title: Delivery and recovery apparatus, method, and applications
Inventor: JEWELL STEPHEN W
IPC: G01V1/38
Filed: 2013-12-10
Abstract: Machinery and methods are described whereby a free flying, remotely operated vehicle (ROV) can safely capture and take on board lightly managed seismic sensor devices (payload) while they are in-transit via a surface vessel in a (deep) water column. ROV payload can be replenished without the need for the ROV to return to the surface vessel to receive additional payload and to do so without the need for heavy launch and recovery machinery. The reverse process of returning payload from the ROV to the surface vessel is also disclosed.
Patent CA-2896394-A1 (CA)
Inventor: AIZPURUA IPARRAGUIRRE JESUS MARIA
IPC: A61L31/06
Filed: 2013-12-26
Abstract: The invention relates to a modified polyaryletherketone (PAEK) polymer having surfaces chemically modified with azides, alkynes, thiols, maleimides, sulphonyl azides or thio acids, suitable for click reactions, and to a method for obtaining it. The invention further concerns conjugated biomaterials derived therefrom, PAEK-type materials having surfaces modified with an RGD (Arg-Gly-Asp) and/or OGP 10-14 (Tyr-Gly-Phe-Gly-Gly) peptidomimetic, and to a method for obtaining it. These materials are particularly useful for manufacturing medical devices. Finally, the invention also relates to a fluorescent PAEK material.
Patent CA-2897659-A1 (CA)
Inventor: FREDERICK LARRY D
IPC: G08B21/00
Filed: 2014-01-09
Abstract: Mechanized area controller systems and methods for coordinating the movement of workers and vehicles to improve safety are disclosed. Some embodiments of the methods include generating a magnetic field defining a first zone and detecting a response signal from a first device. Other method embodiments also include detecting a response signal from a second device and generating a danger signal when the first and second devices are both within the first zone. Some system embodiments include a magnetic field generator for defining a first zone and a first device configured to detect the first zone magnetic field and generate a first device response signal. Other system embodiments also include a second device configured to detect the first zone magnetic field and generate a second device response signal and a first controller configured to generate a danger signal when the first and second devices are both within the first zone.
Patent CA-2899511-A1 (CA)
Inventor: MAJEED MUHAMMED
IPC: A01N63/22
Filed: 2014-12-24
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
Patent CA-2901286-A1 (CA)
Title: Module de decompression
Inventor: SMITH ALAN
IPC: B05B9/04
Filed: 2014-02-10
Abstract: Système de circulation 10 de peinture et module de décompression 40 utilisé dans celui-ci. Le système de circulation 10 de peinture comprend une conduite d'alimentation 22 en peinture sous pression, une conduite de retour 34 au réservoir et un module de décompression 40. Le module de décompression 40 comprend : une première chambre d'écoulement 65 dans laquelle la peinture sous pression est apportée à ladite conduite d'alimentation 22 ; une seconde chambre d'écoulement 69 dans laquelle la peinture revient à ladite conduite de retour 34 au réservoir ; un orifice 42 reliant lesdites première et seconde chambres d'écoulement ; et un élément clapet 46 sollicité vers l'orifice de manière à bloquer ledit orifice. L'élément clapet 46 est mobile en réaction à une pression présente dans ladite première chambre d'écoulement 65 dépassant une pression de relâchement prédéfinie de manière à déplacer ledit élément clapet 46 pour qu'il ouvre ledit orifice 42. Cela permet à la peinture de s'écouler depuis ladite première chambre d'écoulement 65 jusque dans ladite seconde chambre d'écoulement 69, empêchant une panne de survenir dans le système de circulation 10 de peinture.
Patent CA-2904611-A1 (CA)
Title: Coated packaging
Inventor: WEIKART CHRISTOPHER
IPC: C23C16/02
Filed: 2014-03-11
Abstract: A vessel has an interior surface facing a lumen. The interior surface includes a tie coating or layer, a barrier coating or layer, and a pH protective coating or layer. The tie coating or layer can comprise SiOxCy or SiNxCy, where x is from about 0.5 to about 2.4 and y is from about 0.6 to about 3. The barrier coating or layer can comprise SiOx, wherein x is from 1.5 to 2.9. The barrier coating or layer reduces the ingress of atmospheric gas into the lumen. The pH protective coating or layer can comprise SiOxCy or SiNxCy, as well. In an embodiment, in the presence of a fluid composition contained in the lumen and having a pH between 5 and 9, the calculated shelf life of the package can be more than six months at a storage temperature of 4°C.
Patent CA-2906010-A1 (CA)
Inventor: SCHLAM ELLIOTT
IPC: C03C4/16
Filed: 2014-03-14
Abstract: An insulated glazing unit (100) includes a spacer (150) defining a framed area, first and second glazing panes (320) attached to the spacer (150), a pane conductive layer (322) on an inner surface of the first glazing pane (320), and a dielectric layer (324) disposed on the pane conductive layer (322). A shade (310) for use with the insulated glazing unit (100) is affixed to the first glazing pane (320). The shade (310) includes one or more layers selected from a resilient layer (316), a substantially transparent shade conductive layer (318), and an opaque shade conductive layer (325). When an electric drive is applied between the pane conductive layer (322) and the shade conductive layer (318, 325), a potential difference between the pane conductive layer (322) and the shade conductive layer (318, 325) causes the shade (310) to extend from a retracted configuration to an extended configuration. The shade (310) can further include at least one ink coating layer (340) including pigments that selectively reflect or absorb certain visible colors and infrared.
Patent CA-2906089-A1 (CA)
Title: Separation of impurities during extraction processes
Inventor: MCCAULLEY MICHAEL
IPC: C10G31/06
Filed: 2014-03-14
Abstract: A process for the removal of sulfur compounds from a hydrocarbon stream is disclosed. The process includes extractive distillation of a feed stock coupled with a solvent recovery column having a vapor side draw containing the sulfur compound impurities.
Patent CA-2906177-A1 (CA)
Title: Interlocking turret system
Inventor: PORTER JOHN
IPC: F41G1/38
Filed: 2014-03-15
Abstract: A turret system for use with a firearm scope is provided, wherein the turret system comprises a plurality of turrets connected in an interlocked and telescoping orientation. The system may include a first turret having a hollow body and a second turret that may be at least partially received within the hollow body of the first turret. The first turret can be selectively axially movable relative to the second turret such that the second turret may be at least partially exposed when the first turret is in a raised position and the second turret may be substantially covered when the first turret is in a lowered position. The first turret may include a first set of calibration data thereon tailored to a first set of shooting conditions and the second turret may include a second set of calibration data thereon tailored to a second set of shooting conditions.
Patent CA-2908678-A1 (CA)
Inventor: VAUCHEL GUY BERNARD
IPC: F02K1/62
Filed: 2014-06-05
Abstract: Inverseur de poussée d'une nacelle de turboréacteur, comprenant des grilles fixées aux capots mobiles Inverseur de poussée d'une nacelle de turboréacteur, comprenant des capots mobiles (10) qui reculent par rapport à un cadre avant (2) en entraînant par des vérins (20) le basculement de volets (8) se trouvant initialement repliés à l'intérieur de ces capots, pour fermer sensiblement la veine annulaire d'air froid (4), et en ouvrant des grilles (12) disposées autour de cette veine qui reçoivent le flux d'air froid pour le renvoyer vers l'avant, caractérisé en ce que les grilles (12) sont fixées aux capots mobiles (10) et coulissent avec eux.
Patent CA-2910159-A1 (CA)
Inventor: SALTSIDIS PANAGIOTIS
IPC: H04L12/709
Filed: 2014-04-23
Abstract: A method of configuring a set of conversation identifiers (IDs) at a network device in a distributed resilient network interconnect (DRNI) of a link aggregation group is disclosed. The method starts with initializing the set of conversation IDs, wherein the initialization includes setting entries of a Boolean vector associated with the set of conversation IDs to be a sequence of zeroes, and wherein the Boolean vector includes values indicating processing the set of conversation IDs through the single gateway or the single aggregator of the network device. The method continues with determining that distribution of the set of conversation IDs needs to be updated, setting values of an operational vector indexed by the conversation IDs, and setting values of the Boolean vector, wherein the Boolean vector lists whether the single gateway or the single aggregator of the network device is associated with each of the conversation IDs.
Patent CA-2911079-A1 (CA)
Title: Fluorinated carbonates as solvent for lithium sulfonimide-based electrolytes
Inventor: KALHOFF JULIAN
IPC: H01G9/022
Filed: 2014-05-02
Abstract: The present invention relates to an electrolyte solution comprising an electrolyte salt and an electrolyte solvent, wherein the electrolyte solvent comprises a fluorinated acyclic dialkyl carbonate, preferably an n-fluoro diethyl carbonate according to formula (1) as follows : C2H5-xFxCO3C2H5-yFy (1) wherein 1 = x = 5 and 0 = y = 5; in an amount in the range of = 10 wt % to = 100 wt %, referring to a total amount of the electrolyte solvent of 100 wt %, and the use of such fluorinated acyclic dialkyl carbonates for the prevention or suppresion of aluminum current collector corrosion in an alkali or alkaline earth metal-based electrochemical energy storage device, particularly in a lithium-ion battery or lithium polymer battery containing an electrolyte solution comprising an alkali or alkaline earth metal sulfonimide or sulfonmethide salt.
Patent CA-2912768-A1 (CA)
Inventor: BERNAR RODGER FRANCESCO
IPC: C10G49/00
Filed: 2015-11-24
Abstract: Systems and methods for partially upgrading a produced heavy hydrocarbon resource at the production site (at the pad or a central processing facility) using indirect hydrogen addition, comprising a blender for blending the hydrocarbon with a hydrogen donator and a reactor for elevating the mixture to a temperature sufficient to hydrogenate the hydrocarbon to an API level required for pipeline specifications. The partially upgraded hydrocarbon can then be transported by pipeline to a refinery for further processing. The presence of catalysts and on-site hydrogen production equipment conventionally required for upgrading is eliminated. Further, the need for diluent which is conventionally used to enable pipelineability of produced heavy hydrocarbon is reduced or eliminated, thus reducing the diluent freight cost and the required pipeline volume.
Patent CA-2913820-A1 (CA)
Title: Predicting properties of well bore treatment fluids
Inventor: ALBRIGHTON LUCAS D
IPC: G06F19/00
Filed: 2014-07-16
Abstract: Methods and systems for predicting properties of well bore treatment fluids are disclosed. An embodiment includes a method of predicting fluid properties comprising: determining an operational window for a well bore fluid system; collecting data at vertices of the operational window; and developing a model comprising predicted properties for a plurality of data points within the operational window, wherein developing the model uses Barycentric interpolation.
Patent CA-2914289-A1 (CA)
Inventor: ROSENZWEIG LARRY STEVEN
IPC: B32B18/00
Filed: 2015-12-10
Abstract: Article includes a substrate, a bond coat disposed on the substrate, an environmental barrier coating disposed on the bond coat, and a patterned abradable coating disposed on the second top coat. The environmental barrier coating includes an intermediate layer disposed on the bond coat, a sealing layer disposed on the intermediate layer, a first top coat disposed on the sealing layer, and a second top coat disposed on the first top coat. The first top coat is different from the second top coat.
Patent CA-2914461-A1 (CA)
Inventor: KANDULA MAHESH
IPC: C07D213/82
Filed: 2014-02-12
Abstract: The invention relates to the compositions of formula I or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprises a salt of metformin and the methods for treating or preventing metabolic syndrome, prediabetes and diabetes may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of diabetes mellitus, obesity, lipid disorders, hypertriglyceridemia, hyperglycemia, hyperinsulinemia and insulin resistance.