baber/WOPTO huggingface dataset:
Patent JP-2001524029-A (JP)
IPC: B01J49/30
Filed: 1998-05-08
Abstract: A method of treating an ion exchange material, the method including: (a) positioning at least two regions of ion exchange material between an anode and cathode electrode, wherein at least a portion of the two regions being in electrical contact and being separated by a non-ion specific permeable interface; (b) supplying water to the at least two regions; (c) applying an electric potential between the electrodes thereby causing generation of hydrogen ions at the anode and hydroxide ions at the cathode, which ions are caused to move through each region towards the oppositely-charged electrode and thereby displacing at least a portion of any anions or cations associated with the ion exchange material in each region such that the displaced anions and cations are also caused to move through the regions towards the oppositely charged electrode; and (d) removing at least some of the cations and/or anions formed during step (c) which reach the interface.
Patent JP-2002500760-A (JP)
Title: 車輪速度センサの偏差の補償方法
IPC: G01P21/02
Filed: 1998-04-18
Abstract: (57)【要約】
本発明は、信号を形成する要素がセンサホイール上に配置され、信号を形成する要素の所定の数に所定の角度を割り当てることにより、車輪速度の決定が行われ、ホイールがこの角度だけ回転する時間を評価することにより、車輪速度が決定され、信号を形成する要素の偏差およびまたは要素の位置決めの偏差を補償するために、各々の要素について、車輪速度の決定に用いられる補正係数が記憶され、この補正係数が走行運転中更新される、車輪速度センサの不正確さを補償するための方法に関する。センサによって測定された補正されていない車輪回転速度を、計算モデルに基づいて決められた車輪回転速度の基準値と比較し、この比較に依存して補正係数の更新を行う。
Patent JP-2001506138-A (JP)
IPC: C12N1/19
Filed: 1998-05-20
Abstract: The present invention relates to nucleic acids comprising a nucleotide sequence encoding at least a portion of an enzyme which catalyzes the synthesis of chitin in arthropods, inhibitors directed to said enzyme, and a method for developing said inhibitors.
Patent NZ-196561-A (NZ)
Title: Osmotic device for sustained drug delivery to fluid environment
Inventor: BONSEN P
IPC: A61K9/46
Filed: 1981-03-19
Abstract: An osmotically driven device for dispensing an active agent into a fluid environment is disclosed, which device comprises a semipermeable wall surrounding and defining an inner compartment containing an active agent having limited solubility in the fluid, an outlet passageway through the wall for connecting the compartment with the exterior of the device for dispensing the active agent, the device characterized in that the compartment contains a basic compound that generates carbon dioxide gas on being dispensed from the compartment, thereby improving the delivery of the active agent from the device.
Patent NZ-211186-A (NZ)
Title: Process for making fibre-reinforced thermoplastics
Inventor: COGSWELL F N
IPC: C08J5/06
Filed: 1985-02-21
Abstract: A method of producing a fibre reinforced structure by melt impregnation of continuous fibres with a thermoformable polymer melt comprising pre-wetting the filaments of the fibres with a composition containing a melt plasticiser forthethermoformable polymer, priorto introducing the pre-wetted fibres into the melt, optionally removing the plasticiser when the composition contains a polymer miscible with plasticiserto leave polymer coated filaments and introducing the pre-wetted filaments into a polymer melt, optionally a polymer melt containing a melt plasticiser for the melt and preferably removing the plasticiser from the composition by volatilisation.The pre-wetted polymer coated filaments are useful materials as reinforcing fibres for use in processes other than direct melt impregnation. They can be used in the process known as film stacking impregnation or in processes involving initial impregnation using particulate polymers or alternatively in conventional extrusion compounding.
Patent NZ-228942-A (NZ)
Title: Hypodermic needle shield; automatically deflects during use of needle
Inventor: DUFRESNE CHRISTOPHER MICHAEL
IPC: A61M5/32
Filed: 1989-05-02
Abstract: An arrangement of needle shield (10) is provided which may be attached to the hub (16) of a syringe or multiple blood sample holder (12), which shield (10) is flexible and moves out of the way of the needle point (48) for insertion into the skin, and which moves automatically over the contaminated needle (36) at the instant the needle (36) is removed from the skin for shielding the user from accidental needle stick. The arrangement is in one piece and includes an elongated hood-like body (18) which surrounds the needle (36), and includes at one end a blunt front end shield (20), and at the other end a mounting ring (17) for frictionally engaging the hub (16) of a needle holder (12) or syringe. The body (18) includes an integral lock (38) which snaps over the needle (36) for holding the shield body (18) of the invention over the contaminated needle (36).
Patent NZ-229513-A (NZ)
Title: Insect and mite repelling composition containing at least one acylated alpha-amino acid ester derivative
Inventor: KRUGER BERND-WIELAND
IPC: A01N37/46
Filed: 1989-06-13
Abstract: The present invention relates to the use of acylated  alpha -amino acid ester derivatives, some of which are known, as insect and mite repellents. 
<??>The derivatives used according to the invention have the formula 
<IMAGE>
 in which R<1> stands for hydrogen or for an optionally substituted alkyl, alkenyl or alkynyl radical, R<2> and R<5> are identical or different and stand for optionally substituted alkyl, alkenyl or alkynyl radicals and R<3> and R<4> stand for hydrogen, optionally substituted alkyl, aralkyl or aryl or, together with the atom to which they are bonded, form an optionally substituted monocyclic ring.
Patent NZ-234824-A (NZ)
Title: 11-substituted 19-norsteroid esters and pharmaceutical compositions
Inventor: MOGUILEWSKY MARTINE
IPC: A61P5/24
Filed: 1990-08-08
Abstract: Products of general formula (I): <IMAGE> in which R1 denotes an aliphatic hydrocarbon radical, R2 and R3, which are identical or different, denote a hydrogen atom or an alkyl radical, G denotes a hydrocarbon group containing from one to eighteen carbon atoms and optionally one or a number of identical or different heteroatoms, which is linked to the steroid nucleus by a carbon atom, and either X denotes XA, XA being a hydrogen atom, an alkyl radical, an arylalkyl radical or an acyl radical, and in this case Y denotes YA, YA being a group -B-O-CO-A-Z in which B denotes a saturated or unsaturated, linear or branched, divalent aliphatic radical, A denotes either a saturated or unsaturated, linear or branched, divalent aliphatic radical optionally interrupted or terminated by a divalent aromatic radical, or A denotes a divalent aromatic radical and Z denotes one of the functional groups -COOH or -SO3H, it being possible for these functional groups to be optionally converted into salt form or X denotes XB, XB being a group -CO-A-Z in which A and Z are as defined above and Y then denotes YB, YB being one of the groups chosen from -C IDENTICAL C-R4, -CH=CH-R4 or -CH2-CH2-R4, in which R4 denotes a hydrogen atom, a halogen atom, a trialkylsilyl radical, an alkyl radical or a phenyl radical, the said alkyl and phenyl radicals being optionally substituted.
Patent NZ-241572-A (NZ)
Title: Removing refrigerant from cooling system by passing it into adsorption vessel
Inventor: KIROL LANCE D
IPC: F28F1/12
Filed: 1992-02-10
Abstract: The invention disclosed herein relates to an apparatus for being detachably connected to a chemical or refrigeration system for selectively receiving and dispensing a gaseous refrigerant or chemical from and to that system, respectively, including a vessel having a chamber capable of maintaining a pressurized gas therein, gas inlet means for directing the gas: to and from the chamber, and connection means for connecting the gas inlet to a refrigeration or chemical system; a plurality of heat exchange conduits exposed in the chamber for directing heat exchange fluid therethrough and fluid inlet and outlet means communicating exteriorly of the vessel for directing the fluid to and from the conduits, respectively; and a solid adsorbent capable of alternately adsorbing and desorbing the gaseous refrigerant or chemical and positioned in thermal communication with each of the heat exchange conduits.
Patent NZ-242307-A (NZ)
Title: Hydrolysing water insoluble ester with a lipase using an aluminium salt to increase reaction rate
Inventor: YUKO FUJITA
IPC: D21C3/00
Filed: 1992-04-10
Abstract: The invention provides a process for hydrolysis of water-insoluble ester in the presence of a lipase derived from a strain of Humicola, Candida antarctica, Pseudomonas, Chromobacterium or Aspergillus at pH 3-7, characterized by the presence of an aluminium salt, and particularly to such a process for hydrolysis of resin in pulp. It also provides a method of increasing the rate of hydrolysis of water-insoluble ester in the presence of such a lipase, by incorporation of an aluminium salt. Addition of aluminium salt significantly increases the hydrolysis rate of esters in the presence of the above lipases. A strong increase of fat hydrolysis (from c. 50 % to c. 87 % hydrolysis) was found with as little as 10  mu M Al<+++>.
Patent NZ-242359-A (NZ)
Title: Substituted 3-(pyridinylamino)-indoles and benzo[b]thiophenes, pharmaceutical compositions and preparation thereof
Inventor: EFFLAND RICHARD CHARLES
IPC: C07D401/12
Filed: 1992-04-14
Abstract: The present invention relates to compounds of the formula I <CHEM>  where   R1   is hydrogen, loweralkyl, loweralkenyl, loweralkynyl, arylloweralkyl, aminoloweralkyl, loweralkylaminoloweralkyl, formyl, loweralkylcarbonyl, aminoloweralkylcarbonyl or loweralkoxycarbonyl;  the group -X-Y= is <CHEM>  R2 and R3 being independently hydrogen or loweralkyl; W   is hydrogen, halogen, hydroxy, loweralkoxy, arylloweralkoxy or <CHEM> where R4 is hydrogen, loweralkyl or arylloweralkyl; R5 is loweralkyl or arylloweralkyl; or alternatively the group <CHEM>  as a whole is <CHEM>  , R6 being hydrogen, loweralkyl, aryl or arylloweralkyl; and Z   is hydrogen, halogen, loweralkyl, nitro or amino; which are useful for alleviating various memory dysfunctions such as Alzheimer's disease, as modulators of neurotransmitter functions such as serotonergic and adrenergic, and as such are useful as antidepressants, anxiolytics, atypical antipsychotics, antiemetics, and for the treatment of personality disorders such as obsessive compulsive disorders.
Patent NZ-243558-A (NZ)
Title: Recombinant primate antibodies and their production
Inventor: CROWE JAMES SCOTT
IPC: C12N15/13
Filed: 1992-07-14
Abstract: This invention relates to the preparation of recombinant primate antibodies by DNA technology; Micro-RNA techniques for production of the same; recombinant non-human primate antibodies; formulations containing the same; the use of such antibodies in the prophylaxis and treatment of humans, and diagnostic uses of such antibodies.
Patent NZ-292847-A (NZ)
Title: A solid pharmaceutical dosage form contains codeine and a film forming agent or an anionic surface active agent to inhibit extraction of codeine by filtration and/or solvent extraction
Inventor: CHAN SHING YUE
IPC: A61K47/48
Filed: 1995-09-14
Abstract: A solid pharmaceutical dosage form containing codeine further includes a constituent which inhibits extraction of the codeine by filtration and solvent extraction without preventing release of the codeine in the digestive system. Suitable constituents include film forming agents, particularly cellulose derivatives at 1 to 10 % by weight, anionic surface active agents at 0.1 to 3 % by weight and ion exchange resins at 2 to 15 % by weight.
Patent NZ-296581-A (NZ)
Title: A method of identifying genes identified in a microorganisms ability to adapt to changes in its environment
Inventor: SHEA JACQUELINE ELIZABETH
IPC: C12N15/31
Filed: 1995-12-11
Abstract: A method for identifying a microorganism having a reduced adaptation to a particular environment comprising the steps of: (1) providing a plurality of microorganisms each of which is independently mutated by the insertional inactivation of a gene with a nucleic acid comprising a unique marker sequence so that each mutant contains a different marker sequence, or clones of the said microorganism; (2) providing individually a stored sample of each mutant produced by step (1) and providing individually stored nucleic acid comprising the unique marker sequence from each individual mutant; (3) introducing a plurality of mutants produced by step (1) into the said particular environment and allowing those microorganisms which are able to do so to grow in the said environment; (4) retrieving microorganisms from the said environment or a selected part thereof and isolating the nucleic acid from the retrieved microorganisms; (5) comparing any marker sequences in the nucleic acid isolated in step (4) to the unique marker sequence of each individual mutant stored as in step (2); and (6) selecting an individual mutant which does not contain any of the marker sequences as isolated in step (4).
Patent NZ-296848-A (NZ)
Title: Eye imaging system including hand held image capture unit with fibre optic to transmit light to eye
Inventor: SZIRTH BERNARD C
IPC: A61B3/117
Filed: 1995-11-14
Abstract: An eye imaging system having a hand held portable image capture unit connected by cable to a housing. The hand held unit includes a light fiber optic for transmitting light to the eye, imaging and focusing optics, and a charge coupled image device. The connecting housing provides an electrical power source, light source and viewing monitor for viewing an image of the eye.
Patent NZ-305822-A (NZ)
Title: Isolated presenilin genes and use in diagnosing Alzheimer's Disease
Inventor: ST GEORGE-HYSLOP PETER H
IPC: C12N15/12
Filed: 1996-04-29
Abstract: The specification describes the use of a presenilin protein to treat Alzheimer's disease.
Patent NZ-323790-A (NZ)
Title: A process of making aromatic ring fused cyclopentane derivatives indane carboxylates and intermediates
Inventor: ANDEMICHAEL YEMANE WOLDESELASS
IPC: C07C305/26
Filed: 1996-11-08
Abstract: A process for the preparation of 3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives of the formula 1 where A, B, C and D are carbon atoms or three of A, B, C and D are carbon atoms and one is nitrogen R1 is there formula 2 where the substituents R3, R4, and R5 are defined in the specification. The process occurs where Formula 10 to give formula 11 which is treated with an acid chloride to give formula 12, which is then reacted with 12a in the presence of a catalyst to form formula 13 which is reacted with copper complex, and then sodium methoxide in methanol, hydrogenating over Pa, treating with methyl bromoacetate, potassium carbonate in acetone/methanol followed by saponification with Lithium hydroxide, and finally treating the compound with sodium hydroxide to give the desired compound.
Patent NZ-331900-A (NZ)
Title: Catalyst for the preparation of vinyl acetate consisting of gold or palladium and boron
Inventor: ABEL ROLAND
IPC: C07C67/055
Filed: 1997-03-17
Abstract: The invention relates to a process for the preparation of vinyl acetate in a gaseous phase from ethylene, acetic acid and oxygen or gases containing oxygen while simultaneously forming low levels of high-boiling agents on a catalyst which contains palladium and/ or the compounds thereof, gold and/or the compounds thereof and alkali metal compounds on a carrier. The process is characterised in that the catalyst also contains boron or boron compounds.
Patent NZ-332068-A (NZ)
Title: Alpha, alpha-disubstituted arylalkylamine derivatives as calcilytic compounds
Inventor: VAN WAGENEN BRADFORD C
IPC: C07D317/58
Filed: 1997-04-04
Abstract: A compound having the chemical formula shown wherein: R1 is selected from aryl, alkyl, and cycloalkyl, 2-CN-phenyl, 2,3-dichloro phenyl, 2-nitro-phenyl, 2-cyano-3-chloro-phenyl, an optionally substituted pyridyl, an optionally substituted benzothiopyranyl, an optionally carbazole, or alkyl; R2 is selected from alkyl, cycloalkyl, alkyloxy, H, OH, =O, C(O)OH, C(O)O-alkyl, C(O)NHalkyl, C(O)N( alkyl)2, SH, S-alkyl, NH2, NH-alkyl, and N( alkyl)2; R3 and R4 are each independently alkyl or together cyclopropyl; R5 is either an optionally substituted naphthyl having one to four substituents independently selected from methyl, ethyl, isopropyl, methoxy, Cl, F, Br, and  haloalkyloxy; or a substituted phenyl having one to four substituents with at least one substituent in a meta or para position selected from alkyl, methoxy, Cl, F, Br, and  haloalkyloxy, provided that the substituted phenyl may also have 2 to 3 additional substituents; R6 if present is either hydrogen,  alkyl or  alkylenyl, wherein R6 is not present if R2 is =O; Y1 is a covalent bond, alkylene, or alkylenylene; Y2 is alkylene; Y3 is alkylene; Z is selected from a covalent bond, 0, S, NH, N- alkyl, alkylene, alkylenylene, and alkylynylene; Provided that: 1. if Z is either 0, S, NH, or N- alkyl, then Y1 is not a covalent bond; 2. Y1 and Z may together be a covalent bond; 3. R1 is not 6-CN-2-pyridyl; 4. if R5 is 3,4 dimethoxy-phenyl, then R1 is not CH3(CH2)5O-phenyl; 2-cyclopentyl-phenyl; 2-Cl-phenyl; 2-CN-phenyl; 2-(3-furanyl)phenyl; or 4-(1,2,-benzisothiazol); 5. if R5 is 4-methoxy-phenyl, then R1 is not 2-cyclopentyl-phenyl; 2-CH3-phenyl; 2-benzyl-phenyl; 3-CH3, 4-CH3SO2-phenyl; 4-(1,2,-benzisothiazol); 6. if R5 is 4-Cl-phenyl, then R1 is not 2-CH3-phenyl, 5-iso-propyl-phenyl; 2-CH3-phenyl; 4-CH3- phenyl; phenyl; 2-Cl-phenyl; 4-Cl-phenyl; 2-methoxy, 4-CH3CHCH-phenyl; 3,4 CH3-phenyl; 2,4 C113-phenyl; 2,3 CH3phenyl; 2-iso-propyl, 5-CH3-phenyl; pridyl; 1-imidazole; or 4 (1,2,-benzisothiazol); 7. if R5 is 3,5 dimethyl, 4-methoxyphenyl, then R1 is not 4-CH3, 6-CN-2-pyridyl; or thiophenecarboxamide; 8. R1 is not 3-cyano-2-pyridyl; and pharmaceutically acceptable salts and complexes thereof wherein the compound has an IC50 < 10 microM using the Calcium Receptor Inhibitor Assay. The compounds increase serum PTH levels and are useful in the treatment of diseases or disorders characterised by abnormal bone or mineral homeostasis, such as osteosarcoma, periodontal disease, fracture healing, osteoarthritis, rheumatoid arthritis, Paget's disease, humoral hypercalcemia malignancy and osteoporosis.
Patent NZ-334766-A (NZ)
Title: Windshield repair apparatus including crack repair fixture and method
Inventor: THOMAS JONATHAN P
IPC: B05C5/02
Filed: 1997-09-16
Abstract: A windshield repair apparatus of figure 20 includes a fixture (22) for holding an injector (24) wherein the fixture includes plastic legs (34-not shown) for slideably engaging a windshield (26) during sliding movement of the fixture.  A suction cup mechanism (32) enables selective mounting of the apparatus to the windshield (26).  The suction cup mechanism (32) selectively positions the suction cup so as to not interfere with sliding movement of the windshield repair apparatus across the windshield, and allows for deployment of the suction cup (32) against the windshield (26) at the desired time.  The fixture has engagement surfaces for the user's hand during handling of the windshield repair apparatus (20).
Patent NZ-335454-A (NZ)
Title: LH-RH peptide analogues and pharmaceutical compositions containing them
Inventor: DELANSORNE REMI
IPC: A61P15/10
Filed: 1997-11-12
Abstract: LH-RH peptide analogues of the general formula;  A1-A2-W-A3-A4-SPL-A5-A6-Pro-Z,  wherein, A1 is pGlu, AcSar or an aromatic D amino acid, A2 is a direct bond, His, DPhe, DpFPhe or DpClPhe, W is an aromatic L or D amino acid, A3 is Ala, Thr, Ser, DSer, Ser(OBzl) or MeSer, A4 is Tyr, Phe, cPzACAla, L or D Piclys, L or D NicLys or L or D IprLys, SPL is the spirolactam of formula I, A5 is an amino acid with a (C1-C8)alkyl or (C3-C6)cycloalkyl side chain, A6 is L or D (Arg, HArg, Lys, HLys, Orn, Cit, Hcit or Aph), where L or D (Arg and HArg) can be substituted by one or two (C1-C4)alkyl groups and L or D (Lys, HLys, Orn and Aph) can be substituted by an isopropyl, nicotinoyl or picolinoyl group and Z is GlyNH2, DAlaNH2, AzaGlyNH2 or NHR1 where R1 is a (C1-C4)alkyl optionally substituted by a hydroxy or one or several fluorine atoms, a (C3-C6)cycloalkyl or a heterocyclic radical selected from morpholinyl, pyrrolidinyl and piperidyl, and its pharmaceutically acceptable salts.
Patent NZ-501895-A (NZ)
Title: Process and apparatus for treating waste waters
Inventor: BRAUN ULRICH
IPC: C02F1/44
Filed: 1998-06-03
Abstract: A process for utilising waste waters which comprises the separate collection of gray water and/or black water and membrane filtration of the separately collected gray water and/or solids/liquid separation of the separately collected black water. This relates to a process for producing potable water from gray water or one or more of its partial streams. Moreover, an apparatus for producing potable water from gray water and an apparatus for utilising black water and its use is described.
Patent NZ-505977-A (NZ)
Title: Skimmed milk powder substitute and a method for its preparation; useful for the preparation of chocolate and other foods
Inventor: KRUGER CHRISTOF FRIEDRICH KARL
IPC: A23G9/40
Filed: 1999-02-03
Abstract: A skimmed milk powder substitute comprises an intimate mixture of: i) Total milk protein, milk protein concentrate or milk protein isolate ii) Non-fermentable sweetening and/or bulking agent iii) 0-40 weight parts of lactose per 100 weight parts of protein iv) 0-10 weight parts of fat per 100 weight parts of protein. v) One or more salts. Also described is a method for a chocolate product comprising: i) Mixing the skimmed milk powder substitute with cocoa liquor, cocoa butter and a sweetening and/or bulking agent. ii) Refining the mixture. iii) Conching the refined mixture. iv) Mixing the conched mixture with cocoa butter and lecithin v) Tempering the mixture. vi) Forming the tempered mixture into the chocolate product. Also described is a chocolate product made by the above method comprising less than 1% by weight of total fermentable carbohydrates.
Patent NZ-509033-A (NZ)
Title: Piperidine compounds useful as High affinity ligands for nociceptin receptor ORL-1
Inventor: TULSHIAN DEEN
IPC: C07D401/04
Filed: 1999-07-26
Abstract: A piperidine derivative or a pharmaceutically acceptable salt or solvate thereof has the formula (I) wherein: the dotted line represents an optional double bond formed by one of X1 or X2 with the carbon to which R3 is attached; X1 is R5-alkyl, R6-cycloalkyl, R7-aryl, R8-heteroaryl or R10- heterocycloalkyl; X2 is -CHO, -CN, -NHC(=NR26)NHR26, -CH(=NOR26), -NHOR26, R7- aryl, R7-arylalkyl, R7-arylalkenyl, R7-arylalkynyl, - (CH2)vOR13, -(CH2)vCOOR27, -(CH2)vCONR14R15, -(CH2)vNR21R22 or -(CH2)vNHC(O)R21 or X1 is a group of formula (2) and X2 is hydrogen or X1 and X2 together form a spiro group of formula (3); v is 0 to 3; n and q are independently 1 to 3; m and a is 1 or 2; provided that when n is 1 one of R16 and R17 is - C(O)R28 and p is 0 or 1; Q is CH2, O, S, SO, SO2 or NR17; R1, R2, R3 and R4 are independently H or alkyl or R1 and R4 or R2 and R3 or R1 and R3 or R2 and R4 together form an alkylene bridge; Z1 is R7-aryl; Z2 is R7-aryl or alkyl or Z1 and Z are together a group of formula (4); Z3 is hydrogen or alkyl; r, w and v are independently 0 to 3 provided that the sum of w and u is 1 to 3; ring A is fused R7-phenyl ring and R5 to R17, R21 to R26 and R28 are as defined in the specification limited by the provisos listed in the specification. The compounds are useful as nociceptin receptor inhibitors, which can be used in the treatment of pain, anxiety, cough, asthma, depression and alcohol abuse.