baber/WOPTO huggingface dataset:
Patent FI-875169-A0 (FI)
Inventor: YOKOYAMA NAOKATA
IPC: C07D471/04
Filed: 1987-11-23
Abstract: Compounds of the formula IA or IB <CHEM> wherein A represents an optionally substituted saturated divalent grouping which together with the two carbon atoms to which it is attached represents a fused 8, 9, 10, 11 or 12 membered carbocyclic ring selected from cycloocteno, cyclononeno, cyclodeceno, cycloundeceno and cyclododeceno; each unsubstituted or mono-, di-, tri- or tetra-substituted on carbon atoms within A by lower alkyl, lower alkylidene, C3-C7-cycloalkyl, hydroxy, acyloxy, oxo, lower alkoxy, aryl or aryl-lower alkoxy; and when disubstituted on the same carbon atom within A, said carbon atom in each ring is substituted by two lower alkyl or two aryl-lower alkyl groups, or by one lower alkyl or aryl-lower alkyl group and one group selected from hydroxy, lower alkoxy, aryl-lower alkoxy and acyloxy groups; or each disubstituted on the same carbon atom within A by straight chain alkylene of 2 to 6 carbon atoms forming the carbon to which the alkylene chain is attached a spiro-fused 3 to 7 membered ring; or each ring ring; R1 represents lower alkyl, phenyl, or phenyl substituted by one or two radicals selected from lower alkyl, lower alkoxy, halogen and trifluoromethyl; or R1 represents a five-membered unsaturated heterocyclic radical containing one hetero atom selected from sulfur, oxygen, and unsubstituted or lower alkyl substituted amino nitrogen, or a said radical containing two hetero atoms consisting of one imino nitrogen and one member selected from unsubstituted or lower alkyl substituted amino nitrogen, sulfur and oxygen; or R1 represents an unsaturated six membered heterocyclic radical containing one or two nitrogen atoms; or R1 represents a bicyclic benzo-fused five membered unsaturated heterocyclic radical containing one hetero atom selected from sulfur, oxygen and unsubstituted or lower alkyl substituted amino nitrogen; or R1 represents a bicyclic benzo-fused five membered unsaturated heterocyclic radical containing two hetero atoms consisting of one imino nitrogen and one member selected from unsubstituted or lower alkyl substituted amino nitrogen, oxygen and sulfur; or R1 represents a bicyclic benzo-fused 6-membered unsaturated heterocyclic radical containing one or two nitrogen atoms; or R1 represents any of said heterocyclic radicals mono- or di-substituted on carbon by lower alkoxy, lower alkyl or halogen; R2, R3 and R3' independently represent hydrogen or lower alkyl; or tautomers thereof; or a pharmaceutically acceptable salt thereof; are useful as benzodizepine receptor modulators for the treatment of nervous system disorders. Pharmaceutical compositions, methods of preparation and certain intermediates useful as benzodiazepine receptor modulators are also disclosed. They can be prepared for example by reacting a pyridin-4-one-3-carboxylate compound (III) with a compound of formula R @-NH-NH-R1(IV).
Patent FI-880348-A0 (FI)
Inventor: TOENSMANN ARMIN
IPC: E06B3/48
Filed: 1988-01-26
Abstract: A sliding door or sliding window (10) for closure of external walls of buildings, with a number of leaves (14) which are interconnected in an articulated manner and displaceable, is to be formed in such a manner that sealing which is simple and thermally insulating to the maximum extent is brought about with at the same time simple construction and embodiment. To this end, the leaves (14) which are in each case adjacent to one another and interconnected via a common hinge pin (16) so that there is one joint to be sealed per articulation point. Moreover, in each case only one hinge joint is required for the connection of two adjacent leaves (14). The guide devices for displacing the leaves along the horizontal frame beams (15) are connected to a hinge tongue which thus takes on the function of support for the guide devices as well as a hinge function. <IMAGE>
Patent FI-884511-A0 (FI)
Inventor: JARREAU FRANCOIS-XAVIER
IPC: C07J41/00
Filed: 1988-09-30
Abstract: The invention relates to androstane-17-carboxylic acid esters, represented by general formula (I):   <IMAGE>   wherein R1 represents a lower alkyl group containing 1 to 4 carbon atoms, a lower alkyl group containing 2 to 4 carbon atoms substituted by an amino group, or an aralkyl group from 6 to 12 carbon atoms, R2 and R3, which may be the same or different, represent a hydrogen atom or a lower alkyl group containing 1 to 4 carbon atoms, R4 represents a hydrogen atom, a hydroxy group or an acetoxy group, R5 represents a hydroxy or acetoxy group, or R4 and R5 represent together a divalent alkylenedioxy group, R6 represents a hydroxy group, a methoxy group, or an acetoxy group, R7 represents a methyl group or a hydroxymethyl group, R8 represents an hydrogen atom or a hydroxy group and <IMAGE>  represents either a   <IMAGE>  group or a   <IMAGE>  carbon atom having the double linkage in the 4- or 5-position of the steroid nucleus. Such esters are prepared by coupling reaction of the corresponding 14-azido-derivatives with a sugar, followed by a reduction. Application in therapy, especially in the treatment of heart failure.
Patent FI-892273-A0 (FI)
IPC: B29C45/44
Filed: 1989-05-10
Abstract: A container closure (122) comprises a cylindrical molded unitary member defining a top panel (122h) and a skirt depending from the top panel to an open end for securement to the container, the skirt being interiorly tapered (122f) at the open end. The taper begins flush with the outer surface of the skirt (122g) and ends in a first circumference extending radially of the central axis of such cylinder. The skirt further defines a bead (122d) extending radially interiorly of the skirt to a second circumference radially closer to the cylinder central axis than the first circumference. The closure provides sealing retention pressure in accordance with the radially interior extent of the bead and exhibits evidence of an initial removal from the container. In one embodiment, the bead is generally of semispherical configuration and flow passages (122d-1) may exist in the bead, preferably over less than the hemispherical extent thereof. In another embodiment; said skirt further defines front and rear locking tabs (220, 220A, 226) respectively mutually spaced perimetrically at a location above said tapered surface and a bead at a location below said top panel and said locking tabs. The method for making the closures involves the use of a stripper plate (118) to participate in part in defining a mold cavity.
Patent FI-895341-A0 (FI)
Inventor: CERUTTI PETER
IPC: C12Q1/686
Filed: 1989-11-09
Abstract: The invention relates to the direct detection of human papillomavirus DNA. The recently developed polymerase chain reaction has been modified in order to improve sensitivity and specificity. It is possible, by choosing suitable oligonucleotide primers (amplimers) and reaction temperatures, for individual HPV genes to be identified among the total cell 4 DNA and amplified to such an extent that non-isotopic detection is possible. In addition, the use of reverse transcription allows deliberate amplification of spliced mRNA and thus an indication of premalignant or malignant states or lesions.
Patent FI-914789-A0 (FI)
Inventor: WAGNER MANFRED
IPC: B01F23/10
Filed: 1991-10-11
Abstract: The invention relates to a gas burner, especially for glass melting furnaces, with a mixing pipe with a perforated mixing member for mixing burnable gas with air drawn in by the gas flow. 
<??>The new gas burner is characterised in that the perforated mixing member (2) is arranged on the end of an air suction pipe (5), which is movable in the direction of its longitudinal axis, and there is between the perforated mixing member (2) and the inner surface (11) of the mixing pipe (3) a sealing sleeve (10) which allows a movement of the perforated mixing member (2) in the direction of the longitudinal axis. 
<IMAGE>
Patent FI-921589-A0 (FI)
Inventor: EBERLEIN WOLFGANG
IPC: C07D471/04
Filed: 1992-04-10
Abstract: The invention relates to novel condensed diazepinones of the general formula I <IMAGE>  in which     B represents one of the divalent radicals <IMAGE> and   X, l, m, n and R<1> to R<7> are as defined in Claim 1, and in addition to their salts with inorganic or organic acids and a process for their preparation. The substances are used to improve or normalise disorders of cerebral perfusion due to arteriosclerosis, to treat diseases of the central nervous system, in particular Alzheimer's disease and Parkinson's disease, and as vagal pacemakers for the treatment of bradycardias and bradyarrhythmias, and also for improving memory power.
Patent FI-922865-A0 (FI)
Inventor: GUSS BENGT MIKAEL
IPC: C07K1/14
Filed: 1992-06-18
Abstract: The present invention relates to a new recombinant hybrid-DNA-molecule comprising a nucleotide sequence from S. aureus coding for a protein, or polypeptide, having collagen binding properties.
Patent FI-923591-A0 (FI)
Inventor: HERGET GERHARD
IPC: C09D7/62
Filed: 1992-08-11
Abstract: The invention concerns surface-modified flake-like substrates, as well as their production from particles coated with organic aluminium compounds. Organic silicon compounds may also be added to the modifying agent. Such substrates are highly suitable for use as substrates for other modified products and can be used in paints, printing inks, varnishes, coating powders, plastics, cosmetic preparations, and in bronzing processes.
Patent FI-925115-A0 (FI)
Inventor: EGRAZ JEAN-BERNARD
IPC: C11D3/37
Filed: 1992-11-11
Abstract: Water-soluble polymers and/or copolymers possessing enhanced biodegradability, and their applications are disclosed. Acrylic and/or vinyl polymers and/or copolymers containing acid groups, in which 35% to 90% of the active acid sites are neutralized by magnesium ions, the specific viscosity is at most 25, and biodegradability is enhanced. Their decomposition after 36 days is greater than 50% as measured by the modified Sturm test. These polymers can be used in industries as varied as: paper-making, paints, plastics, petroleum, drilling fluids, water treatment, detergents, cosmetics, textiles, inks, leather, grinding and/or splitting of minerals in water.
Patent FI-935486-A0 (FI)
Inventor: ROFFMAN JEFFREY H
IPC: G02C7/04
Filed: 1993-12-08
Abstract: An ophthalmic lens provides a cumulative ratio of distance to near focal length that is predominantly distance correction under high illumination, nearly evenly divided under moderate illumination, and favoring again distance vision correction under low level illumination. The lens is specifically adjusted to match the patient's pupil size as a function of illumination level, in the preferred embodiment by applying pupil size parameters as a function of age. This lens has the properties of matching both the distribution of near and distance focal vision correction to the type of human activity typically undertaken in various illumination conditions, as well as matching particular lens dimensions to suit the size of the pupil as a function of illumination intensity.
Patent FI-940913-A0 (FI)
Inventor: JOHNSTON JAMES A
IPC: H05K3/00
Filed: 1994-02-25
Abstract: A component for use in manufacturing articles such as printed circuit boards comprising a laminate of a sheet of copper foil and a sheet of metal or the like. A band of flexible adhesive joins the sheets around their borders and creates a protected central zone at the interface of the sheets. Islands of adhesive are located inwardly of the edges of the sheets through which tooling pin holes may be formed to facilitate handling of the foil.
Patent FI-941499-A0 (FI)
Inventor: CHEE U HIRAM
IPC: A61F5/00
Filed: 1994-03-30
Abstract: A device for occluding a blood vessel comprising a helical metal coil having at least one fibrous element attached to its proximal end wherein the fibrous element(s) extends in a sinusoidal wave configuration, the loops of which extend about individual windings at spaced intervals along the axis of the coil.
Patent FI-942258-A0 (FI)
Inventor: HAAG E KEITH
IPC: E04B1/12
Filed: 1994-05-13
Abstract: Cap means embodying the concepts of the present invention are adapted to secure one or more roof panel members to a modular building structure. Broadly, such a cap means has a horizontally disposed base portion that is adapted to engage a supporting member incorporated in, and presented from, the modular building. An inclined, plate portion is supported from the base portion. The plate portion is adapted to receive, and support, the roof panel. A locking member secures each roof panel to one or more inclined plate portions. The cap means may also provide a facia member which may be attached to the roof panels with connector that inhibit removal. The cap members can provide space for the installation of electrical cable in a location that can be accessed either before or after erection of the building.
Patent FI-951964-A0 (FI)
Inventor: MUELLER GEORG
IPC: B65H27/00
Filed: 1995-04-25
Abstract: The carrier or support roller has: (a) hollow cylindrical carrier mantle (1) pref. of steel, and (b) an outer coating (3) on the mantle surface. The coating (3) has a thickness of 5-12 mm, and pref. 6-8 mm. The coating (3) is of a low-wear elastomer and especially a nitrile or polyurethane rubber with a hardness of 65-80 Shore A and pref. 70-74 Shore A. An elastomer layer can be inserted between the roller mantle (1) and outer coating (3). <IMAGE>
Patent IL-66957-A0 (IL)
Title: Substituted urea derivatives,their preparation and their use as herbicides and plant growth regulators
IPC: C07D239/46
Filed: 1982-10-11
Abstract: N-phenylsulfonyl-N'-pyrimidinyl- and -triazinylureas of the general formula   <IMAGE>   and the salts of these compounds with amines, alkali metal or alkaline-earth metal bases or with quaternary ammonium bases have good selective, pre- and post-emergence, herbicidal and growth-regulating properties. The symbols in this formula have the following meanings: A is a C3-C6-alkynyl group, a C1-C6-alkyl group which is substituted by halogen, C1-C4-alkoxy, C1-C4-alkylthio, C1-C4- alkylsulfinyl, C1-C4-alkylsulfonyl, C1-C4-haloalkoxy, C1-C4-haloalkylthio, C1-C4-haloalkylsulfinyl or C1-C4-haloalkylsulfonyl, or it is a C2-C6-alkenyl group substituted by one of the above substituents, E is the methine group or nitrogen, X is oxygen, sulfur, or a sulfinyl or sulfonyl bridge, Z is oxygen or sulfur, m is the number one or two, R1 is hydrogen, halogen, C1-C5-alkyl, C2-C5-alkenyl, or a -Y-R6 group, R2 is hydrogen, halogen, C1-C5-alkyl, C2-C5-alkenyl or C1-C4-haloalkyl, or a group -Y-R6, -COOR7, -NO2 or -CO-NR8-R9, R3 is hydrogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkylthio, C1-C4-haloalkyl, C1-C4-haloalkoxy, halogen or alkoxyalkyl having at most 4 carbon atoms, R4 is hydrogen, methyl or ethyl, R5 is hydrogen, C1-C4-alkyl, C1-C3-alkoxy, methoxymethyl, cyanomethyl or cyanoethyl, R6 and R7 are each C1-C5-alkyl, C2-C5-alkenyl or C2-C6-alkynyl, R8 and R9 independently of one another are each hydrogen, C1-C5-alkyl, C2-C5-alkenyl or C2-C6-alkynyl, and Y is oxygen, sulfur, or a sulfinyl or sulfonyl bridge, and A can also be C2-C6-alkenyl when X is oxygen.
Patent IL-86342-A0 (IL)
Title: Process and intermediates for the preparation of certain histamine h2-antagonists
IPC: A61K/
Filed: 1988-05-11
Abstract: Cyclobutene derivs. of formula (I) are used in prepn. of cyclobutene derivs. of formula (V), or their non-toxic pharmaceutically acceptable salts, by (a) reacting (I) with a phenol deriv. of formula (III) in an inert solvent, or mixed aq./organic solvent, in presence of a base and opt. a catalyst to give a cpd. of formula (IV); and (b) reacting with an amine of formula R1NH2. - In formulae, R1 = H or lower alkyl; R2 and R3 = lower alkyl; or NR2R3 = pyrrolidino, methylpyrrolidino, piperidino, methylpiperidino, homopiperidino, heptamethyleneimino, or octamethyleneimino; R = lower alkyl or cyclohexyl; and X = leaving gp.
Patent IL-89520-A0 (IL)
Title: Isonicotinic acid amides,their preparation and their use for protecting plants against disease
IPC: C07D413/14
Filed: 1989-03-07
Abstract: Novel substituted isonicotinic acid amides of the general formula <IMAGE>  in which X in ortho/ortho'-position are equal and represent fluorine, chlorine, bromine or iodine; Q1 is unsubstituted pyridimin-4-yl, or pyrimidin-4-yl substituted by R1, R2 and R3; Q2 is unsubstituted pyrimidin-2-yl, or pyrimidin-2-yl substituted by R1, R2 and R3; Q3 is unsubstituted pyrimidin-5-yl, or pyrimidin-5-yl substituted by R1, R2 and R3; Q4 is pyridin-2-yl, pyridin-3-yl or pyridin-4-yl each of which is unsubstituted or substituted by R1, R2 and R3; Q5 is pyridazin-3-yl or pyridazin-4-yl each of which is unsubstituted or substituted by R1, R2 and R3; Q6 is unsubstituted pyrazin-2-yl, or pyrazin-2-yl substituted by R1, R2 and R3; R1, R2, R3 are hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl having from 1 to 3 halogen atoms, C1-C6alkoxy, C2-C6alkoxyalkyl, C1-C6thioalkyl, C1-C6haloalkoxy having from 1 to 5 halogen atoms, C3-C6alkenyloxy, C3-C6alkynyloxy, C3-C6thioalkenyl, C3-C6cycloalkyl, C3-C6cycloalkyl substituted by methyl, or nitro, cyano, the radical CH(OR4)2 or COOR4 in which R4 is C1-C4alkyl; also phenyl, phenoxy, thiophenyl, benzyl, benzyloxy or thiobenzyl; or phenyl, phenoxy, thiophenyl, benzyl, benzyloxy or thiobenzyl each substituted at least once by C1-C3alkyl, C1-C3-alkoxy, C1-C3haloalkyl having from 1 to 3 halogen atoms, halogen, nitro or by cyano; and also N(R5)R6 in which R5 and R6, independently of one another, are each C1-C6alkyl; and furthermore piperidinyl, pyrrolidinyl, morpholinyl, imidazolyl or triazolyl, or piperidinyl, pyrrolidinyl, morpholinyl, imidazolyl or triazolyl each substituted by C1-C3alkyl, C1-C3alkoxy, C1-C3haloalkyl having from 1 to 3 halogen atoms, halogen, nitro or by cyano. The novel active ingredients have plant-protecting properties and are suitable especially for the preventive protection of plants against attack by phytopathogenic microorganisms such as fungi, bacteria and viruses.
Patent IL-99184-A0 (IL)
Title: Nickel-cobalt-iron base alloy and articles made therefrom
IPC: C22C19/00
Filed: 1991-08-14
Abstract: A precipitation strengthenable, nickel-cobalt-iron base alloy and articles made therefrom are disclosed. The alloy contains controlled amounts of silicon, nickel, cobalt, iron, chromium, niobium, titanium, and aluminum which are critically balanced to provide a unique combination of high strength, good ductility, and controlled thermal expansion, together with good thermal stability and good oxidation resistance up to about 1200 degrees F. or higher.
Patent IL-99439-A0 (IL)
Title: Regulating nucleotide sequence for initiation of transcription
IPC: C12N/
Filed: 1991-09-08
Abstract: The invention relates to a recombinant nucleotide sequence, characterized in that it comprises: a regulatory sequence of the initiation of tanscription, this regulatory sequence containing a promoter in association with the motif GCACTC 9N GAGTGC, in which "N" signifies any one of the 4 bases thymine, guanine, adenine and cytosine; a sequence coding for a polypeptide, called "heterologous polypeptide", which is different from that naturally associated with the said promoter; the said coding sequence being positioned downstream from the said regulatory sequence of the initiation of transcription at a site which, under suitable conditions, would allow the expression of the polypeptide under the control of the said promoter.
Patent AU-PP967799-A0 (AU)
Title: Methods to implement sealing and electrical connections to single cell and multi-cell regenerative photovoltaic photoelectrochemical devices
IPC: H01G9/20
Filed: 1999-04-09
Abstract: A regenerative photoelectrochemical (RPEC) device comprising two substrates, wherein: one or both substrates are transparent and are coated with transparent electrical conductor (TEC) layer; one or more layers of porous wide band gap semiconductor is/are applied to selected area of said TEC layer and sensitised with dye; electrolyte is placed between said two substrates; hole(s) made in one or both said substrates to enable external electrical connection(s) to said RPEC device.
Patent AU-PQ797700-A0 (AU)
Title: Vaccine
IPC: A61K39/39
Filed: 2000-06-06
Abstract: The present invention relates to a vaccine composition comprising a carbohydrate polymer comprising mannose and flu antigen(s) (e.g. whole inactivated influenza virus) in admixture, and a method of immunising a subject comprising the step of administering the vaccine composition to a subject.
Patent FI-20001716-A0 (FI)
Inventor: KARLSTROEM JOHAN TORE
IPC: E04C3/14
Filed: 2000-07-27
Abstract: The present invention relates to a stud system where each respective stud ( 2 ) includes flanges ( 4, 4 a) which are directly attached to each other and which constitute an essentially monolithic entity. Said flanges are formed of a wane edge wood material ( 3 ) in such a manner that each respective flange includes a bevelled side portion ( 6 ) which is directed towards the inner portion of said stud. A side portion is formed as a contact surface ( 8 ) for intermeshing co-operation with a corresponding contact surface ( 8 ) at an adjacent flange. The present invention also relates to a method for manufacturing such studs where a first flange strip ( 4 ) is formed to include a generally toothed first contact surface ( 8 ) which is arranged in an inter-mesching disposition with a corresponding contact surface ( 8 ) at a corresponding second flange strip ( 4 a). Further, the present invention relates to a method at such stud systems. A side portion of respective opposite flanges ( 4, 4 a) are formed to include longitudinal tongue structures and two opposite flanges ( 4, 4 a) are compressed so that said opposite tongue structures will be positioned in a mutually intermeshing disposition.
Patent IL-108231-A0 (IL)
Title: Environmentally-friendly tampon assembly and its production
IPC: A61F13/15
Filed: 1993-12-30
Abstract: An environmentally-friendly tampon assembly of the type which includes an inner sleeve, an outer sleeve and an absorbent pledget has inner and outer sleeves which are fabricated from a biodegradable, flushable material such as paper. The outer sleeve has an inwardly extending tang for preventing movement of the pledget during retraction of the inner sleeve. The tang is also formed of biodegradable material, and may be formed of material which is from the same blank out of which the outer sleeve was formed. Six different methods of forming the outer sleeve and tang are disclosed.   <IMAGE>
Patent IL-108820-A0 (IL)
Title: Ophthalmic lens with anti-toxin agent
IPC: G02B1/04
Filed: 1994-03-02
Abstract: An ophthalmic lens for placement on the anterior surface of the eye is disclosed. The lens has impregnated in it or it has coated on its surface an ester of a polyhydric aliphatic alcohol and a fatty acid in which the alcohol residue has at least one hydroxyl group. The ester is present in an amount which is effective to prevent or decrease the release of bacterial toxins when the lens is exposed to those toxins. The lens is particularly well-suited for a soft hydrogel contact lens, and advantageously eliminates, minimizes or prevents keratitis. Bacterial keratitis is an infection of the cornea of the eye which may occur during extended wear of the lens and may cause ulceration of the cornea.
Patent IL-109685-A0 (IL)
Title: Gastric acid secretion inhibiting compounds
IPC: C07D215/40
Filed: 1994-05-19
Abstract: PCT No. PCT/SE94/00552 Sec. 371 Date Jul. 1, 1994 Sec. 102(e) Date Jul. 1, 1994 PCT Filed Jun. 8, 1994 PCT Pub. No. WO94/29274 PCT Pub. Date Dec. 22, 1994The present invention relates to novel quinoline derivatives of the formula   <IMAGE>   which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.