baber/WOPTO huggingface dataset:
Patent CA-2681978-A1 (CA)
Title: Heterocyclic spiro-compounds
Inventor: BENNACER BIBIA
IPC: C07D491/20
Filed: 2008-03-27
Abstract: The patent application relates to new heterocyclic compounds of the general formula (I), in which R, R1, R2, Q, T, n and p have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldosterone synthase inhibitors.
Patent CA-2684762-A1 (CA)
Inventor: BOLES ECKHARD
IPC: C12N9/90
Filed: 2008-03-20
Abstract: The present invention relates to novel expression cassettes and expression vectors, comprising three nucleic acid sequences for araA, araB and araD, each coding for a polypeptide of an L-arabinose metabolic pathway, in particular, a bacterial L-arabinose metabolic pathway. The invention particularly relates to expression cassettes and expression vectors, comprising codon-optimised nucleic acid sequences for araA, araB and araD. The invention further relates to host cells, in particular modified yeast strains containing the expression cassettes or expression vectors and expressing the polypeptides for the L-arabinose metabolic pathway, in particular, for the bacterial L-arabinose metabolic pathway. When using these modified host cells, arabinose is more effectively fermented by these cells, in particular into ethanol. The present invention is therefore relevant, inter alia, in connection with the production of biochemicals from biomass, such as bioethanol for example.
Patent CA-2686819-A1 (CA)
Inventor: INABA TAKESHI
IPC: F02B77/13
Filed: 2009-12-02
Abstract: An outboard motor S has an upstream intake silencer with an upstream expansion chamber, and a downstream intake silencer disposed under the upstream intake silencer. The upstream expansion chamber has a lower wall of a stepped shape including a raised part overlapping the downstream intake silencer in a plane and a lowered part without overlapping with the downstream intake silencer in a plane and at a level lower than that of the raised part. An upstream outlet passage of the upstream intake silencer is formed in the raised part. The downstream intake silencer has a stepped upper wall having a raised part, and a lowered part underlying the lower wall of the upstream expansion chamber in a plane and extending at a level lower than that of the raised part. A downstream inlet passage of the downstream intake silencer is formed in the lowered part of the upper wall. The respective stepped shapes complementary to each other of the lower wall of the upstream intake silencer and the upper wall of the downstream intake silencer are utilized for enhancing the intake noise reducing effect of the intake silencers and for forming the outboard motor in reduced vertical size by compactly stacking up the intake silencers.
Patent CA-2687060-A1 (CA)
Title: Multi power sourced electric vehicle
Inventor: BOYS JOHN TALBOT
IPC: H02J7/00
Filed: 2008-05-09
Abstract: An inductive power transfer (IPT) pad and system for the charging of elec tric and hybid electric vehicles. The batter of such a vehicle can be select ively coupled to a high power electrical supply for fast charging or a lower power electrical supply for charging using IPT. The batteries of the vehicl es are used in a system to control the load demand in an electricity network through variations of the frequency of power supplied.
Patent CA-2687218-A1 (CA)
Title: Methods of screening nucleic acids for single nucleotide variations
Inventor: DAHLHAUSER ERIC B
IPC: C12Q1/68
Filed: 2008-05-14
Abstract: Disclosed are methods and compositions for detecting variation in nucleic acids. The disclosed method compares the sequence of a nucleic acid of interest with the sequence of a reference nucleic acid to sensitively identify variations between the sequence of a nucleic acid of interest and the sequence of a reference nucleic acid. The disclosed method generally involves excision and replacement of selected nucleotides in nucleic acid strands hybridized to other strands. In the method, if the excised nucleotide was mismatched with the nucleotide in the other, hybridized strand, then the replacement nucleotide will not be mismatched. If the excised nucleotide was not mismatched with the nucleotide in the other, hybridized strand, then the excised nucleotide is not replaced. This difference allows detection of variation in the nucleic acid of interest. In some forms of the method, by replacing excised nucleotides with nuclease-resistant nucleotides, strands in which excised nucleotides are replaced will be resistant to nuclease digestion while strands in which excised nucleotides are not replaced will be sensitive to nuclease digestion. By exposing the hybridizing nucleic acids to nuclease following replacement of excised nucleotides, the strands in which excised nucleotides are not replaced can be destroyed by the nuclease while strands in which excised nucleotides are replaced can be preserved. The remaining strands can then be detected and whether the strand survived nuclease digestion can be noted. Strands that survive nuclease digestion are indicative of the presence of variation in the nucleic acid of interest.
Patent CA-2691459-A1 (CA)
Inventor: RUDGE DAVID ALAN
IPC: C07D405/12
Filed: 2008-07-04
Abstract: A compound of the formula (I): wherein: R represents one or more optional substituents on the fused cyclohexene ring; X can be NR X or CR X R Y; if X= NR X then n is 1 or 2 and if X= CR X R  Y then n is 1; if X= NR X, then R X is selected from the group consisting of H, optionally substituted C1-20 alkyl, optionally substituted C5-20 aryl, optionally substituted C3-20 heterocyclyl, optionally substituted amido, optionally substituted thioamido, optionally substituted ester, optionally substituted acyl, and optionally substituted sulfonyl groups; if X = CR X R Y then R X is selected from the group consisting of H, optionally substituted C1-20 alkyl, optionally substituted C5-20 aryl, optionally substituted C3-20 heterocyclyl, optionally substituted amido, optionally substituted thioamido, optionally substituted sulfonamino, optionally substituted ether, optionally substituted ester, optionally substituted acyl, optionally substituted acylamido, and optionally substituted sulfonyl groups and R.gamma. is selected from H, hydroxy, optionally substituted amino, or R x and R.gamma. may together form an optionally substituted spiro-C3-7 cycloalkyl or heterocyclyl group; R C1 and R C2 are both hydrogen, or when X is CR X R Y, R C1, R C2, R x and R y, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo. The compounds act as inhibitors of poly(APD-ribose)synthase, PARP-1.
Patent CA-2692158-A1 (CA)
Inventor: PETRI ELIZABETH
IPC: H04K1/00
Filed: 2008-06-17
Abstract: A system for making financial transfers between subscribers of a financial transfer service is disclosed.   The system may include a receiving subscriber interface (RSI), a sending subscriber interface (SSI), and an agent server (AS). The RSI may be configured to accept a set of invoice information including an identifier of a destination account. The SSI may be configured to accept a set of payment information including an identifier of a source account. The AS may be configured to receive the set of invoice information and create an invoice based on the set of invoice information. The AS may also be configured to transmit the invoice and receive the set of payment information.   The AS may also be configured to cause an amount of funds to be transferred from the source account on a source transfer network to the destination account on a destination transfer network via a primary transfer network.
Patent CA-2693358-A1 (CA)
Title: Digital broadcasting system and data processing method
Inventor: LEE CHUL SOO
IPC: H04N19/89
Filed: 2008-07-25
Abstract: A digital broadcasting system and a method of processing data are disclosed. A  receiving system of the digital broadcasting system may include a signal receiving unit, a demodulating unit, a demultiplexer, and an audio/video decoder. The signal receiving unit receives a broadcast signal including main service data and an RS frame including a plurality of MPH service data packets. The demodulating unit demodulates data of the RS frame. The demultiplexer identifies an MPH service data packet including an IP datagram of mobile service data with reference to an MPH  header of each MPH service data packet in the RS frame, and when a stuffing data is inserted in the identified payload of MPH service data packet, removes the stuffing data from the payload and separates an audio and video data from IP datagram of the mobile service data of the payload, and outputs the separated audio and video data.
Patent CA-2693747-A1 (CA)
Inventor: LAUZON VINCENT
IPC: G07F17/34
Filed: 2008-07-14
Abstract: The present invention relates to a reel-type slot machine having interactive spin action visual effects. The reel-type slot machine includes at least M reels, each reel having symbols associated with it; a video display for displaying a video image of a M N matrix of squares, each square associated with a symbol of a corresponding reel; and a spin actuator for initiating play and interactively producing spin action visual effects associated with the M x N matrix of squares by inputting a direction vector and speed, wherein the direction vector and speed respectively determine the direction and speed of the spin action visual effects. Preferably, the spin actuator is a trackball.
Patent CA-2693954-A1 (CA)
Inventor: NEWCOMB MARK D
IPC: A23K1/00
Filed: 2008-07-15
Abstract: A system for measuring starch gelatinization in a feed production system. The system includes a feed production system configured to generate an extruded feed from a feed mixture using a combination of steam and pressure to cook the feed in an extruder, a near infrared spectrometer configured to measure a degree of starch gelatinization for the extruded feed, and a starch gelatinization measurement engine configured to generate a measurement of the degree of starch gelatinization in the extruded feed.
Patent CA-2694238-A1 (CA)
Inventor: FLANDERS PAUL
IPC: A61K31/56
Filed: 2008-06-27
Abstract: The present invention relates to pharmaceutical compositions and in particular to suspension aerosol pharmaceutical compositions, processes to obtain them and their use in inhalation therapy.
Patent CA-2694898-A1 (CA)
Inventor: BERG-SLOT JOHANNA JACOBA
IPC: C07C15/04
Filed: 2008-07-28
Abstract: A catalyst composition which comprises: a) a carrier which comprises at least 30 wt% of a binder selected from silica, zirconia and titania; at least 20 wt% of a pentasil zeolite, having a bulk silica to alumina ratio in the range of from 20 to 150 and being in its H+ form; and less than 10 wt% of other components, all percentages being on the basis of total carrier; b) platinum in an amount in the range of from 0.001 to 0.1 wt%, on the basis of total catalyst; and c) tin in an amount in the range of from 0.01 to 0.5 wt%, on the basis of total catalyst; its preparation and use; are provided.
Patent CA-2695356-A1 (CA)
Inventor: GADINI COSTANZO
IPC: A47L15/44
Filed: 2008-08-06
Abstract: A support (40) contains a plurality of separate doses (46) of deliverable substances. The support is arranged to be operatively coupled to a long-life dispensing device. The support is intended to be either coupled to or inserted within the dispensing device, such that a relative movement of the support and at least one part of the dispenser body that is caused by an actuating system allows selectively delivering at least one substance dose. The support integrates reference means (49a), (49b) that are configured to provide, due to said relative movement, information on at least one of : -doses of the substance provided within the support, - a condition and/or a position of the support within the dispenser.
Patent CA-2698343-A1 (CA)
Inventor: WU ANNA M
IPC: A61K39/395
Filed: 2008-09-04
Abstract: The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis, prognosis, treatment, visualization, and the like.  The present invention also provides methods for the detection, visualization, and treatment of various cancers expressing PSCA.
Patent CA-2701405-A1 (CA)
Inventor: FONTAINE MIKE
IPC: F02K1/80
Filed: 2010-04-22
Abstract: A gas turbine engine case having a working fluid flow, includes inner and outer case portions defining an annular duct for directing the working fluid flow, and a plurality of struts positioned within the annular duct and extending between the inner and outer case portions. The struts are welded to the inner and outer case portions with a first weld along a peripheral line of the respective struts and with second weld, of fillet type, in selected locations for additionally connecting a portion of each strut to the respective inner and outer case portions.
Patent CA-2702869-A1 (CA)
Inventor: KRIESELS PETRUS CORNELIS
IPC: E21B7/20
Filed: 2008-11-19
Abstract: A method of drilling a wellbore (1) into an earth formation is disclosed. The method comprises arranging a drill string (6) and an expandable tubular element (8) coaxially in the wellbore, the drill string having an axially extending fluid passage (30), the tubular element surrounding the drill string and having a lower end bent (12) radially outward and in axially reverse direction so as to form an expanded tubular section (10) extending around a remaining tubular section of the tubular element, said lower end defining a bending zone of the tubular element, wherein an annular space is formed between the. drill string and the remaining tubular section.
Patent CA-2705453-A1 (CA)
Inventor: HARASYMIW GREGORY
IPC: A61K9/00
Filed: 2008-11-10
Abstract: Provided are compositions comprising aqueous solutions of valsartan suitable for oral administration, preferably in pediatric and geriatric populations. Methods for making such compositions and methods for their stabilization are provided.
Patent CA-2705709-A1 (CA)
Inventor: CHAVATTE KRIS
IPC: A61B17/34
Filed: 2008-11-13
Abstract: The present invention is directed to a porous or permeable containment device for implanting into the interior volume of a targeted vertebral body for use in restoring the anatomy of the targeted vertebral body. The containment device is expandable from an insertion configuration to an expanded configuration via, for example, a bone filler material. The containment device preferably permits the bone filler material to flow out of the containment device via, for example, one or more pores, one or more flow-directing tentacles, etc. so that the bone filler material may interdigitates with the surrounding bone tissue. The containment device is preferably configured to have a pre-determined, dog-bone'shape, when in the expanded configuration. The containment device preferably also includes one or more knobs or ribs to facilitate anchoring of the containment device to the surrounding bone tissue, one or more air or fluid evacuation pores to permit air or fluid from escaping from the interior volume of the containment device and/or one or more radiopacity rings or markers to enable a surgeon to locate and/or position the containment device under X-ray imaging.
Patent CA-2706359-A1 (CA)
Inventor: WORLEY EMMETT RONALD
IPC: B01D45/08
Filed: 2010-06-03
Abstract: An apparatus for separating natural gas from production streams comprising a liquid dispersion of water, sand, and natural gas is provided for. The separator comprises a vessel having an interior surface defining a spherical interior space. The interior space allows a production stream introduced therein to experience a velocity drop sufficient to allow separation of the natural gas from the sand and water components. The separator also comprises a stream inlet port in the vessel, a liquid drain in the lower end of the vessel, and a gas outlet port at the upper end of the vessel remote from the stream inlet port. A baffle is mounted in the interior of the vessel in the path of the production stream between the stream inlet port and the gas outlet port. The baffle is effective to spread and direct a high pressure production stream introduced into the interior space via the stream inlet port downward toward the liquid drain.
Patent CA-2715510-A1 (CA)
Inventor: ESCOLA PUIG-CORVE ALEJANDRO
IPC: E04H12/22
Filed: 2008-12-16
Abstract: The invention relates to a drilling/clamping device including a base body which can be extracted from the shaft or rod, provided at one end with a drilling head actuated by means of an electric motor housed inside the base body.  The base body also includes means for coupling to the shaft or rod, provided with means for actuating an electrical contactor element in order to actuate the electric motor. In addition, a rising/falling pivoted connection is provided between the coupling means and the base body, such that, when pressure is applied to the rod or shank the coupling means move axially and abut against the contactor element associated with the electric motor, thereby starting the electric motor.
Patent CA-2715672-A1 (CA)
Inventor: NELSON ALAN FREDERICK
IPC: A01N25/28
Filed: 2009-02-12
Abstract: The present invention relates, inter alia, to a herbicide formulation comprising:  (a) an aqueous phase; (b) an HPPD inhibitor in suspension in the aqueous phase; (c) an encapsulated chloroacetamide herbicide in suspension in the aqueous phase; (d) glyphosate and/or glufosinate or an agrochemically acceptable salt thereof, in solution in the aqueous phase, and (e) toluene sulfonic acid in an amount to provide a pH between about 3 and about 7. The invention further relates to a process for the preparation of an herbicide formulation of the invention and to a process for the control of unwanted vegetation.
Patent CA-2716951-A1 (CA)
Inventor: AHRENDT KATERI A
IPC: A61K31/437
Filed: 2009-02-27
Abstract: Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula (I) and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
Patent CA-2717745-A1 (CA)
Inventor: FRANK CHRISTOPHER
IPC: G06F17/30
Filed: 2009-03-04
Abstract: The present invention provides a system and mobile device for providing geographic information to a user. The system includes a mobile device that is wirelessly connected to a geographic database.  The mobile device includes a plurality of sensors for determining a first location and a first direction. A  controller is adapted to provide information requested based on local queries and distal queries. In addition, the controller can respond to thematic queries of each variety, wherein the database search is limited to objects, entities or features that fit within a selected theme. Finally, the controller is adapted to select and order query results based upon two- and three-dimensional query windows.
Patent CA-2718444-A1 (CA)
Title: Interaction control of cationic biocides using labile anionic polyelectrolytes
Inventor: KETELSON HOWARD ALLEN
IPC: C09K23/56
Filed: 2009-03-25
Abstract: Methods of inhibiting the uptake of cationic biocides into medical devices such as contact lenses and implants are described. Methods of stabilizing emulsions containing cationic biocides are also described. In particular, the present invention provides for the use of polymers acting as labile anionic polyelectrolytes to reversibly bind cationic biocides. The reversible binding can reduce the deleterious effects of cationic biocides while maintaining biocidal activity. Preferred polymers include galactomannan and polyvinyl alcohol.
Patent CA-2722749-A1 (CA)
Title: Device platform for medical procedures
Inventor: DILLON TRAVIS E
IPC: A61B19/00
Filed: 2009-04-24
Abstract: The present embodiments provide apparatus and methods suitable for facilitating positioning one or more medical components. In one embodiment, the apparatus comprises a rail member having proximal and distal ends and a generally longitudinal axis. A first connector is adapted to be selectively coupled to the rail member, and a first medical component is adapted to be coupled to the first connector. The first connector is disposed for selective longitudinal movement along the rail member, thereby permitting movement of the first medical component with respect to the rail member. In this manner, one or more components, such as a catheter and a needle, may be inserted into a human or animal body in a controlled fashion with respect to one another.
Patent CA-2723747-A1 (CA)
Inventor: MCCANN DANIEL
IPC: H04L9/14
Filed: 2009-05-05
Abstract: A system, peripheral device, and method for authenticating an encryption key before transmitting encrypted messages containing sensitive information are provided. Authentication of a client device during the coordination of data transfer among multiple computer devices is possible by providing a peripheral device that does not have a direct connection to a network, but rather, any message to be transmitted over the network must be relayed through a client device. Any sensitive information to be transferred to a remote device is in-serted into a message, then the message is encrypted in the peripheral device. This prevents any process running on the client device from fooling the client device into communicating confidential information to a third party rather than the desired remote computer, because the client device never sees the sensitive information in an unencrypted form; only the peripheral device has access to the sensitive information in an unencrypted form.
Patent CA-2723944-A1 (CA)
Inventor: BALZARINI JAN
IPC: A61K31/513
Filed: 2009-05-15
Abstract: The present invention relates to a combination of therapeutic agents comprising: (a) a cytosine-based anti-cancer drug and/or a purine-based anticancer drug and (b) a therapeutic agent selected from the group consisting of thymidine phosphorylase inhibitors, and antibiotics against Mollicutes bacteria. The present invention also relates to the simultaneous, separate or sequential use of said combination for the treatment of cancer in mammals, especially in humans. The present invention also relates to methods of treatment of cancer, preferably in mammals infected with Mollicutes bacteria.
Patent CA-2724206-A1 (CA)
Inventor: OCIO ENRIQUE
IPC: A61K33/243
Filed: 2009-05-18
Abstract: Methods for treating cancer by using compound PM00104, in particular, for treating multiple myeloma are provided.
Patent CA-2724449-A1 (CA)
Inventor: MANNING DAVID D
IPC: C07D487/04
Filed: 2009-05-28
Abstract: Novel 5-HT3 receptor modulators are disclosed, in particular compounds of the formula (See formula I) These compounds are used in the treatment of various disorders, including chemotherapy-induced nausea and vomiting, post-operative nausea and vomiting, and irritable bowel syndrome. Methods of making these compounds are also described in the present invention.
Patent CA-2724702-A1 (CA)
Inventor: CORNELIUS TIM
IPC: F03B13/10
Filed: 2009-04-14
Abstract: A central axis water turbine is described which comprises a turbine body having a central axis; a rotor mounted on the turbine body for rotation about the central axis, the rotor comprising a central hub supporting a plurality of blades, each blade extending from a blade root mounted on the hub to a blade tip; a generator driven by the rotor; and a housing surrounding the rotor and adapted to direct water flow towards the rotor, the housing converging from a front opening forward of the rotor to a nar-rower throat adjacent the turbine body; wherein the blades are splayed rearward from the blade root to the blade tip by a tilt angle of 1° to 20° from a plane perpendicular to the central axis.