baber/WOPTO huggingface dataset:
Patent ES-2735809-T3 (ES)
Title: Derivativos del ácido siálico para la derivatización y conjugación de proteínas
Inventor: JAIN SANJAY
IPC: C08B37/00
Filed: 2004-08-12
Granted: 2019-12-20
Abstract: Un procedimiento de producción de un derivativo aldehído de un ácido siálico en el que un material de partida que tiene una unidad de ácido siálico en el terminal reductor y una unidad de sacárido terminal en el extremo no reductor que tiene un grupo diol vecinal se somete a las etapas secuenciales de: a) oxidación selectiva preliminar para oxidar el grupo diol vecinal a un aldehído b) reducción para abrir reductivamente el anillo en la unidad de ácido siálico terminal reductor, por lo que se forma un grupo diol vecinal, y en el que el aldehído formado en la etapa a) también se reduce para formar un grupo hidroxi que no es parte de un grupo diol vecinal; y c) oxidación selectiva para oxidar el grupo diol vecinal formado en la etapa b) para formar un grupo aldehído.
Patent ES-2428967-T3 (ES)
Title: Dispositivo tubular de cierre de foramen oval permeable (FOP) con sistema de retención
Inventor: CHANDUSZKO ANDRZEJ J
IPC: A61B17/08
Filed: 2004-07-14
Granted: 2013-11-12
Abstract: Dispositivo de oclusión (20) para un defecto, adaptado para ser introducido en el cuerpo a través del sistemavascular, teniendo el dispositivo de oclusión (20) un lado proximal (40) y un lado distal (30) que cooperan para cerrarel defecto, un tubo central (22) dispuesto entre el lado proximal (40) y el lado distal (30), incluyendo los ladosproximal y distal (40, 30) del dispositivo de oclusión (20) hendiduras (41, 31) formadas axialmente en el dispositivode oclusión (20) para formar secciones de medio tubo (91a, 91b) y secciones de cuarto de tubo (92a, 92b, 93a, 93b),en el que las hendiduras (41) en el lado proximal (40) están desviadas rotacionalmente de las hendiduras (31) en lalado distal (30) alrededor de la circunferencia del dispositivo de oclusión (20) y las secciones de medio tubo (91a,91b) y las secciones de cuarto de tubo (92a, 92b, 93a, 93b) forman pétalos (32) cuando la longitud axial deldispositivo de oclusión (20) se acorta en un estado desplegado, en el que al menos dos secciones de medio tubo (91a, 91b) unidas al tubo central (22) forman cada una, una partede dos pétalos adyacentes (32a, 32b) que se extiende desde las al menos dos secciones de medio tubo (91a, 91b) yen el que al menos otras dos secciones de medio tubo (94a, 94b) unidas al lado proximal o distal (40, 30) deldispositivo de oclusión (20) forman cada una, una parte de dos pétalos adyacentes (32a, 32b) que se extiendedesde las al menos otras dos secciones de medio tubo (94a, 94b) en el que una primera parte de cada pétalo (32a) está formada por una sección de medio tubo (91b) unida al tubocentral (22) y una segunda parte de cada pétalo (32a) está formada por una sección de medio tubo (94a) unida allado proximal o distal (40, 30) del dispositivo de oclusión (20), estando dichas secciones de medio tubo primera ysegunda (91b, 94a) unidas por una sección de cuarto de tubo (92b) para formar el pétalo completo (32a).
Patent ES-2304631-T3 (ES)
Inventor: TSETI IOULIA
IPC: A61K31/198
Filed: 2004-11-18
Granted: 2008-10-16
Abstract: A device comprising an inhaler suitable for administration of a stable dry powder blend is described, which contains a blend comprising a thyroid hormone, in particular levothyroxine sodium, and other additives such as lactose particles, sodium starch glycolate, magnesium stearate, and talc silicified.
Patent ES-2387088-T3 (ES)
Title: Cartucho de tinta, aparato de registro de inyección de tinta, y conjunto de cartuchos de tinta
Inventor: MIYAZAWA HISASHI
IPC: B41J2/175
Filed: 2002-04-03
Granted: 2012-09-13
Abstract: Un cartucho de tinta adaptado para introducirse extraiblemente en una region de montaje (120, 121, 122, 123) deun aparato de registro que tiene una pluralidad de electrodos (106) y una aguja de suministro de tinta (102),incluyendo el cartucho de tinta (1):un orificio de suministro de tinta (4) conectable a la aguja de suministro de tinta (102), estando situado el orificio desuministro de tinta en un lado de extremo delantero en una direccion de introduccion del cartucho de tinta en laregion de montaje;paredes primera y segunda una enfrente de otra, siendo la primera pared sustancialmente paralela a la direccion deintroduccion del cartucho de tinta en la region de montaje;medios de memoria (7) que tienen una pluralidad de electrodos (7a) conectables a los electrodos (106) de la regionde montaje, estando dispuestos los electrodos de los medios de memoria (7) en la primera pared del cartucho, laprimera pared tiene una primera parte superficial en la que estan dispuestos los electrodos (7a) de los medios dememoria (7); el orificio de suministro de tinta (4) tiene un eje (A) que se extiende en una direccion de eje Y paralela ala direccion de introduccion,caracterizado por:un elemento de retencion (5) dispuesto en la primera pared y que tiene una porcion de enganche (5a) movil conrelacion a la primera pared que esta situada en un de extremo de salida, con respecto a la direccion de introduccion,con relacion a los electrodos (7a) de los medios de memoria (7), y que se puede enganchar con una porcion deenganche (107) de la region de montaje, donde los electrodos (7a) de los medios de memoria (7) se puedenconectar a los electrodos (106) de la region de montaje cuando la porcion de enganche (5a) del elemento deretencion (5) engancha con la porcion de enganche (107) de la region de montaje; dondela primera parte superficial esta a nivel o rebajado de una segunda parte superficial en la que esta dispuesto elelemento de retencion (5), yla porcion de enganche (5a) del elemento de retencion esta sustancialmente alineada con al menos uno de loselectrodos (7a) de los medios de memoria (7) en la direccion de eje Y.
Patent ES-2305935-T3 (ES)
Inventor: ROUSSEAU ROBERT A
IPC: A61B17/12
Filed: 1997-10-01
Granted: 2008-11-01
Abstract: A clip module (23) comprises: a module housing (32) which forms a cavity having first and second channels (72, 74) therein to house a ligation clip (26) and a pusher (34); a Y-shaped clip track (28) having two arms and a U-shaped clip body (30) with a slot for slidably engaging the clip track (28) and closing the arms of the clip track (28) about a vessel during application by the applicator (92); a frustoconical section (50) with opposing tapered beveled portions (66) that enhance visibility along the longitudinal axis of the module housing (32) and a reduced diameter section (52) for attachment to the applicator (92). In operation, module (23) is attached to the applicator (92) wherein an advancing element of the applicator (92) forces the pusher (34) inside the module housing (32). The pusher (34) then engages the clip body (30) which slides over the clip track (28) to ligate the vessel between two arms of the track (28).
Patent ES-2405601-T3 (ES)
Title: Conjunto de construcción con adoquines
Inventor: GEIGER PETER
IPC: E01C5/06
Filed: 2005-06-16
Granted: 2013-05-31
Abstract: Conjunto de construcción con cuerpos de piedra esencialmente rectangulares de material de hormigón conalturas uniformes y con superficies laterales verticales, con una pluralidad de cuerpos de piedra dispuestos en seriecon longitudes y anchuras iguales o de tamaño diferente, en el que el conjunto de construcción, especialmente parala formación de un paquete de instalación rectangular o cuadrado que puede ser agarrado con una máquina,comprende una pluralidad de series de cuerpos de piedra formados, dispuestos paralelos adyacentes entre sí, y enel que los conjuntos de construcción pueden formar en el compuesto de instalación, en la zona de las piedrasextremas de las series de cuerpos de piedra unas junturas continuas de forma lineal, y opcionalmente a través de lasustitución de conjuntos de construcción próximos, adyacentes a piedras extremas en serie de diferente longitud, sepuede conseguir la formación de junturas esencialmente en forma de meandro, en el que al menos una zona parcialde la superficie de limitación superior de los cuerpos de piedra está arqueada en forma de arco hacia fuera y unosapéndices dispuestos en las partes de patas de los cuerpos de piedra están dispuestos a distancia entre sí en lassuperficies laterales de las piezas de patas, en el que los apéndices forman cuerpos de apoyo para cuerpos depiedra adyacentes y los apéndices junto con apéndices de cuerpos de piedra adyacentes permiten la formación deespacios intermedios en las zonas de las junturas que sirven como orificios de paso del agua, caracterizado por queel conjunto de construcción comprende tanto adoquines como cuerpos de piedra, cuya relación entre longitud yaltura es inferior o igual al número 4, como también al menos una placa como cuerpo de piedra, cuya relación entrelongitud y altura es mayor que el número 4 y en el que los bordes de adoquines y de placas adyacentes presentanalturas diferentes.
Patent ES-2311903-T3 (ES)
Inventor: SCHMITT KARL-HEINZ
IPC: E01F15/04
Filed: 2005-06-23
Granted: 2009-02-16
Abstract: At least one U-shaped or trapezoidal support bar (13) which is open to a guide board (8) is installed between the guide board and a post (5). The longitudinal edges (15) of the support bar engage in longitudinal depressions (17) in the guide board.
Patent ES-2339674-T3 (ES)
Inventor: STAUDNER REINHARD
IPC: E01C9/04
Filed: 2005-08-19
Granted: 2010-05-24
Abstract: A railway level (10) crossing for road vehicles has a first group (26) of base panels (28) arranged parallel (L) with the rails. The crossing further has a second group (94) of panels arranged parallel (L) with the rails. Each group (24, 94) has a cover layer (96) assembled from panels linked by tie-bars. The panels are made of recycles automotive tyres.
Patent ES-2310309-T3 (ES)
Inventor: JAECKLIN VICTOR DR
IPC: F16H25/24
Filed: 2005-09-09
Granted: 2009-01-01
Abstract: The linear drive comprises a spindle (9). The rotating motion of the spindle (9) is transformed into a linear motion of a part of the transmission unit located in the output area (3) of the linear drive. The part is permanently linked to a joint element connecting the linear drive to the part to be adjusted. The connection can be released with an adjusting unit (14) in order to facilitate a motion of the linear drive independent of the motor (2). This particular adjustment is performed by manually rotating the spindle (9) and the part of the transmission unit in relation to each other in a predetermined direction.
Patent ES-2302132-T3 (ES)
Inventor: SERR MARTIN
IPC: D21F9/00
Filed: 2005-07-27
Granted: 2008-07-01
Abstract: The covering (2, 3) includes supporting locations on the side facing the fibrous web. Their density is in the range 1400/cm 2>to 1700/cm 2>or more. They are formed by thread crossing points in the weave, and run in the machine- and transverse directions. The thread configuration is circular or flattened in relation to the plane of the covering, especially elliptical in cross section. Diameter of the circular threads ranges from 0.13 mm down to 0.08 mm or less. The covering is a self-stitched binding (SSB). The covering is a membrane, the supports being formed by raised locations. These are points or hills (27) facing the fibrous web, elsewhere the surface is planar. Raised locations have a height of up to 0.08 mm and their diameter is 0.1-0.4 mm. The thickness is especially less than 0.58 mm. The number of empty spaces within the fabric on the side facing the fibrous web is less than or equal to the corresponding number on the opposite side. The side facing the web is ground down or calendered. In a variant, the raised portions are formed by a casting mold, injection molding, boring, or spark erosion. The fibrous web is produced a rate of up to 1800 m/min or more.
Patent ES-2314598-T3 (ES)
Inventor: LASSERRE PIERRE-ANDRE
IPC: B65D83/20
Filed: 2005-10-14
Granted: 2009-03-16
Abstract: The device has an actuator with a diffuser (40), and a trigger (60). The trigger is in support against the diffuser to move the diffuser to actuate a pump to dispense a product. The diffuser is connected, before the pump`s initial actuation, to a ferrule (30) by a bridge (50) in a position so that the diffuser is not in fluidic communication with the pump. The trigger has a stem limiting trigger`s movement to restrict pump`s actuation. The diffuser has a tube that extends along a perpendicular axis distinct from a longitudinal axis of the pump. An independent claim is also included for an utilization of a device for packaging and dispensing a product such as a cosmetic product, in the form of a cream, gel, foam or a spray.
Patent ES-2302170-T3 (ES)
Inventor: BENEDETTI PAOLO
IPC: B65D41/04
Filed: 2005-12-01
Granted: 2008-07-01
Abstract: There is described a method of producing plastic tops (1) for sealed containers of pourable food products; the method starts with a plastic sheet material having a layer of gas-barrier material, and includes the steps of forming a contoured body (11) having an annular base portion (2, 12), and a neck portion (3, 13), which projects from the base portion (2, 12), defines, with the base portion, a pour opening (5) of the container, and is closed, on the opposite side to the base portion (2, 12), by a disk-shaped member (15); applying a cap (8) to the neck portion (3, 13); making a cut (16) along the periphery of the disk-shaped member (15) and on the side facing the pour opening (5); and joining the disk-shaped member (15), by adhesion, to a portion (10) of the cap (8) superimposed on the disk-shaped member, so that the disk-shaped member (15) defines a layer of gas-barrier material of the cap (8).
Patent ES-2348161-T3 (ES)
Inventor: IWAMOTO TAKASHI
IPC: A61K39/00
Filed: 2005-03-11
Granted: 2010-11-30
Abstract: The present invention relates to the use of cytoxicity based on the effector function of anti-GFRA1 antibodies. Specifically, the present invention provides methods and pharmaceutical compositions that comprise an anti-GFRA1 antibody as an active ingredient for damaging GFRA1-expressing cells using antibody effector function. Since GFRA1 is strongly expressed in breast, gastric, liver, renal or lung cancer cells, the present invention is useful in breast, gastric, liver, renal or lung cancer therapies.
Patent ES-2297685-T3 (ES)
Inventor: HUTTON KENNETH M
IPC: F23J3/02
Filed: 2005-03-02
Granted: 2008-05-01
Abstract: A sootblower frame particularly adapted for long retracting-type sootblowers for cleaning of internal surfaces of large scale combustion devices. The frame, preferably formed from sheet metal stock, incorporates integrally formed surfaces and configuration features which provide for guiding and movement of the sootblower carriage assembly. The side panels of the frame further provide the surface for the mounting of the drive rack by which the carriage is advanced and retracted along the frame.
Patent ES-2293565-T3 (ES)
Title: Una puerta.
Inventor: COSTELLO TIMOTHY FRANCIS
IPC: E06B3/82
Filed: 2005-04-29
Granted: 2008-03-16
Abstract: Una puerta, que comprende un par de subunidades de plástico idénticas (11) unidas dorso con dorso, teniendo cada subunidad un revestimiento de plástico externo con una pluralidad de formaciones verticales (12) dispuestas sobre su superficie (13) que mira hacia adentro, no siendo visibles las formaciones verticales (12) desde el exterior de la puerta (10), y estando alineadas las formaciones verticales (12) de la subunidad (11) con las de la otra subunidad (11) para formar la puerta (10) que tiene una estructura monocasco.
Patent ES-2311986-T3 (ES)
Inventor: HELLBERG MARK R
IPC: A61K31/401
Filed: 2005-04-25
Granted: 2009-02-16
Abstract: The use of HMG-CoA reductase inhibitors (e.g., statins) to treat glaucoma, control intraocular pressure, preserve the trabecular meshwork, protect against ocular neurodegeneration and/or protect against glaucomatous retinopathy is described. The preferred HMG-CoA reductase inhibitors, which are statins having an RI value of 0.2 to 0.7 (e.g., pravastatin), are administered via topical application to the affected eye(s) of the patient.
Patent ES-2365023-T3 (ES)
Inventor: CRINE PHILIPPE
IPC: A61K47/64
Filed: 2005-04-21
Granted: 2011-09-20
Abstract: The invention relates to a pharmaceutical composition comprising a bone delivery conjugate having the structure Z-sALP-Y-Dn-X, wherein X is absent or is an amino acid sequence of at least one amino acid; Y is absent or is an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; Dn is a poly aspartate, wherein n=10 to 16; and sALP is a soluble alkaline phosphatase and uses thereof.
Patent ES-2317272-T3 (ES)
Inventor: KELLNER GERD
IPC: F42B12/20
Filed: 2005-06-21
Granted: 2009-04-16
Abstract: The aim of the invention is to obtain great final ballistic effectiveness of fragmentation bullets and warheads regardless of the impact speed while using as little explosive material as possible. Said aim is achieved by combining explosive shell (3) with a damming inner member (4) in connection with an accelerated outer jacket (2). This arrangement results in the best possible conversion of the explosive energy while offering great creative flexibility regarding the design. A wide range of additional possible effects is created by blast-compacting the inner damming member (4). Furthermore, the shape of the inner damming member allows the fragments to obtain a directionally controlled effect. Depending on the caliber and technical design, the amount of explosive material used can be reduced by 50 to 80 percent compared to conventional explosive bullets at comparable fragment speeds or sub-bullet speeds. The explosive material economized is available as additional effective mass. The accelerated jacket (2) can also be entirely or partly composed of preformed fragments or sub-bullets.
Patent ES-2293593-T3 (ES)
Inventor: JAWORSKI THOMAS
IPC: A01M1/20
Filed: 2005-06-29
Granted: 2008-03-16
Abstract: An apparatus for dispensing a volatile substance includes an electromechanical d ispenser (2) attached to a pivot arm (29), and a cartridge (60) for holding a pl urality of reservoirs (31) each containing a volatile substance. The cartridge (60) is rotatable such that any one of the reservoirs (31) can be positioned in an engagement position, in which the volatile substance can be dispensed. The c artridge (60) has a cam feature consisting of a contoured circumferential surfac e that alternately rises and falls. The pivot arm (29) operates in tandem with the cam feature such that, when the cartridge (60) is rotated, the dispenser alt ernately engages and disengages from successive reservoirs (31), and remains out of the path of motion traversed by the reservoirs (31) as the cartridge (60) ro tates from one engagement position to a subsequent engagement position. The ele ctromechanical dispenser (20) may be a piezoelectrically actuated vibratory type liquid atomization apparatus, and the volatile substance may be a fragrance.
Patent ES-2320360-T3 (ES)
Title: Formulacion farmaceutica que comprende un antibiotico, un triazol y un corticosteroide.
Inventor: HUQ ABU
IPC: A61K31/56
Filed: 2005-08-10
Granted: 2009-05-21
Abstract: Una composición farmacéutica para el tratamiento de una infección ótica en un animal que comprende orbifloxacina o una de sus sales farmacéuticamente aceptables; una cantidad antifúngicamente eficaz de un compuesto de triazol farmacéuticamente aceptable, furoato de mometasona monohidrato y al menos un vehículo farmacéuticamente aceptable, en la que dicha composición es una suspensión.
Patent ES-2378829-T3 (ES)
Inventor: BECQ FREDERIC
IPC: A61K31/55
Filed: 2005-10-14
Granted: 2012-04-18
Abstract: The invention relates to paullone derivatives for the production of medicaments for the treatment of mucoviscidosis and diseases related to protein addressing errors in cells, said derivatives being of general formula (1): wherein X-C-O, C-S-CH3, C-S, -C-NHOH, Z-C or N, Y- with the adjacent ring, a phenyl or thienyl group, the ring(s) of said derivatives being optionally substituted with one or more halogen atoms, hydroxy, alkylenehydroxy, alkynealkylenehydroxy, alkynehydroxycyclohexyl, alkyl, alkoxy, alkylenealkoxy, or alkylenecyano groups where the alkylene group is either saturated or unsaturated, the groups having a straight or branched chain with C1 to C18, said chain being optionally substituted with one or more hydroxy or amino groups, or one or more trifluoromethyl, -COM, -COOM, or -CH2COOM groups (where M=H, C1 to C18 straight or branched chain alkyl, optionally substituted with one or more hydroxy and/or amino groups) nitroso, or cyano, R5-H, or C1 to C5 alkyl and R12-H, or -C-CO2-(CH3)3 and the physiologically-acceptable salts and derivatives thereof.
Patent ES-2303699-T3 (ES)
Inventor: GIMBRES DAVID
IPC: F02B77/08
Filed: 2005-11-25
Granted: 2008-08-16
Abstract: The invention relates to a device for determination of the quantity of NOx emitted by a diesel engine ( 10 ) in a motor vehicle with common-rail fuel supply means ( 12 ) for the cylinders thereof, of the type comprising pressure recording means ( 32 ) in at least one cylinder of the engine and means ( 50 ), for determining the mass fraction of oxygen in the mixture admitted into the cylinder. Said device comprises means ( 58, 68 ), for determining a temperature of the flame front on combustion of the mixture, means ( 52 ), for determining the mass of fuel burnt in the cylinder and means ( 70 ), for calculating the quantity of NOx emitted by the combustion of the mixture in the cylinder as a function of the recorded pressure, the mass fraction of oxygen in the mixture, the temperature of the flame front and the mass of fuel burnt.
Patent ES-2444511-T3 (ES)
Title: Desespumantes para aplicaciones de pasta y elaboración de papel
Inventor: CHENG HUAI N
IPC: B01D19/04
Filed: 2005-12-08
Granted: 2014-02-25
Abstract: Una composición basada en aceite que se utiliza para controlar la espuma, que comprende: a) de aproximadamente el 6 a aproximadamente el 93 % en peso de al menos un aceite de triglicérido o mezclade aceite de triglicérido, b) de aproximadamente el 12 a aproximadamente el 93 % en peso de una silicona, c) de aproximadamente el 0,2 a aproximadamente el 12,0 % en peso de un agente de estabilización de siliconatriglicérido, d) de aproximadamente el 0,2 a aproximadamente el 12,0 % en peso de una sílice hidrófoba, e) de aproximadamente 0 a aproximadamente el 12,0 % en peso de uno o más agentes tensioactivos ydispersantes, f) de aproximadamente 0 a aproximadamente el 10 % de uno o más espesantes, y donde cada uno del aceite de triglicérido, mezcla de aceite de triglicérido, silicona, agente de estabilización desilicona-triglicérido así como agentes tensioactivos y dispersantes tienen puntos de evaporación instantáneasuperiores a 60 ºC (140 ºF).
Patent ES-2329275-T3 (ES)
Inventor: MEURS WILHELM
IPC: A01B61/04
Filed: 2006-05-19
Granted: 2009-11-24
Abstract: The reversible plow has an overload safety system comprising a hydraulic cylinder (9) mounted between the T-shaped plow-beam (2) and a console (6) connecting it to the machine frame (7). Diagonal supporting strips (15, 16) are pivoted on the console, their opposite ends being connected to the cylinder.