baber/WOPTO huggingface dataset:
Patent UY-36862-A (UY)
Title: Conjugados anticuerpo anti-dll3-fármaco y métodos de uso
Inventor: SCOTT J DYLLA
IPC: C07K16/30
Filed: 2016-08-19
Abstract: Se proporcionan nuevos anticuerpos anti-DLL3 y conjugados anticuerpo-fármaco, y métodos de uso de tales anticuerpos anti-DLL3 y conjugados anticuerpo-fármaco para tratar cáncer.
Patent UY-37097-A (UY)
Title: Purificación y decoloración de polímeros
Inventor: Justin Drew SEARCY
IPC: C08G63/90
Filed: 2017-01-27
Abstract: Los métodos de acuerdo con la presente invención decoloran un polímero al mezclar una solución del polímero con un fotocatalizador y al exponer la mezcla a luz ultravioleta; a modo de ejemplo no limitante, el polímero puede ser un polímero estrella y el fotocatalizador puede ser dióxido de titanio. Los métodos de acuerdo con la presente invención también utilizan un eliminador de metal, en algunas formas de realización un eliminador de metal en fase sólida, para eliminar un catalizador metálico de una solución polimérica; a modo de ejemplo no limitante, el catalizador metálico puede ser un catalizador metálico.
Patent UY-38665-A (UY)
Title: Agentes antiproliferativos para el tratamiento de pah
Inventor: BEHENNA DOUGLAS CARL
IPC: C07D471/04
Filed: 2020-04-16
Abstract: La presente invención se refiere a compuestos de la Fórmula I I en donde A, R1, R2, R3 y R4 son como se definen en la presente, y las sales de estos aceptables desde el punto de vista farmacéutico; a composiciones farmacéuticas que comprenden tales compuestos y sales; a métodos para usar tales compuestos, sales y composiciones para tratar hipertensión pulmonar y enfermedades relacionadas, tal como hipertensión arterial pulmonar; a métodos de usar tales compuestos, sales y composiciones para tratar el crecimiento anormal, tal como cáncer; y a procesos para elaborar tales compuestos, sales y composiciones.
Patent UY-38986-A (UY)
Title: Compuestos derivados de 3-(5-metoxi-1-oxoisoindolin-2-il) piperidin-2,6-diona, métodos de usos de los mismos y combinaciones farmacéuticas
Inventor: BONAZZI SIMONE
IPC: C07D413/14
Filed: 2020-12-16
Abstract: La presente divulgación se relaciona con composiciones farmacéuticas y compuestos de fórmula (I) y con su uso para reducir los niveles de expresión de los Motivos de Dedos de Zinc Ampliamente Interespaciados (WIZ), o para inducir la expresión de la hemoglobina fetal (HbF), y para el tratamiento de trastornos sanguíneos hereditarios (hemoglobinopatías, por ejemplo, beta-hemoglobinopatías), tales como la enfermedad de células falciformes y la beta-talasemia.
Patent YU-50198-A (YU)
Inventor: ROBERT PLATZ
IPC: A61K9/48
Filed: 1997-05-07
Abstract: Postupak za pripremu izuzetno finog praska bioloških makromolekula koji uključuje atomiziranje tečnih rastvora makromolekula, sušenje kapljica koje nastaju prilikom atomiziranja, i sakupljanje čestica koje nastaju kao rezultat sušenja. Odgovarajućom kontrolom svakog pojedinog koraka atomiziranja, sušenja i sakupljanja, mogu se pripremati izuzetno fine smeše praska koje imaju osobine posebno pogodne za plućno unošenje sa terapeutskim i drugim namenama.
Patent YU-51785-A (YU)
Title: Process for microencapsulation
Inventor: SCHER H B
IPC: A01N25/28
Filed: 1985-03-29
Abstract: Novel microcapsules are disclosed in which a liquid material which is substantially insoluble in water is enclosed within a solid permeable shell of etherified urea-formaldehyde polymer, prepared by a process which comprises: (a) providing an organic solution comprising said material and a urea-formaldehyde prepolymer in which from about 50% to about 98% of the methylol groups of said prepolymer have been etherified with a C4-C10 alcohol; (b) creating an emulsion of said organic solution in an aqueous solution comprising water and a surface-active agent, wherein said emulsion comprises discrete droplets of said organic solution dispersed in said aqueous solution; (c) causing in situ self-condensation of said urea-formaldehyde prepolymers by adding to said emulsion an acidifying agent and maintaining said emulsion at a pH of between about 0 and about 4 for a sufficient period of time to allow substantial completion of in sttu condensation of said resin prepolymers to convert the liquid droplets of said organic solution to capsules consisting of solid permeable polymer shells enclosing said liquid material; and (d) heating said emulsion to a temperature between about 20 DEG C and about 100 DEG C to cause curing of said in situ formed polymers.
Patent YU-52692-A (YU)
Title: Podsklop kočnice za vozilo
Inventor: MOINARD P
IPC: B60T7/04
Filed: 1992-05-20
Abstract: Pronalazak se odnosi na podsklop kočnice za vozilo koje ima motorski odeljak i putničku kabinu razdvojene pregradnim zidom (46), pri čemu taj podsklop obuhvata jedan pneumatski pojačavački servomotor koji se upravlja pomoću pedale (28) a pričvršćen je na pregradni zid (46), a taj servomotor sadrži, koaksijalno, prednje kućište (14), sa cilindričnim zidom, i zadnji poklopac (16), pri čemu u unutrašnjosti ima dve komore, (18, 20), razdvojene hermetički klipom (22) sa dijafragmom (26) koja obezbeđuje zaptivanje između dveju komora, glavni cilindar (10) pričvršćen za prednje kućiŠte (14) i najmanje jednu pedalu kočnice. Prema pronalasku, kućište (14) i poklopac (16) su izvedeni sa po jednim radijalnim perifernim obodom, pri čemu obod (52) poklopca naleže neposredno na obod (50) kućišta, a koji naleže na pregradni zid (46) sa strane putničke kabine, pri čemu poklopac (16) ima kružni ispust (56) koji se pruža u servomotor, i čiji unutrašnji kraj pritiska radijalno ivični kraj dijafragme (26) na cilindričan zid kućišta (14), a poklopac (16) ima više rebara (36) koja se pružaju od njegovog spoljne zida i od kojih neka rebra (36) obrazuju nosače (34) osovine (32) pedale (28).
Patent YU-63895-A (YU)
Inventor: MIROLJUB DIMIC
Filed: 1995-10-02
Abstract: Mikro bojler direktni ima za osnovu pronalaska podsklop grejača pokretnog (Sgp), sastavljenog od izolacionog cilindra (C), na čijim su krajevima hermetički zalepljeni metalni držači (D) sa urezanim navojem u centralnom otvoru, a nerastegnuta spirala grejača navijanjem krajeva obezbedjuje spoj između ulaznog držača (D) i ventila (V), čije telo pretstavlja klip presostata, a otvaranje ventila (V) vrši se pri naslonu na šuplji kontaktnik (K), te se sa protokom tečnosti istovremeno ostvaruje i električno kolo grejača, pod uticajem mrežnog napona priključenog na držače (D), i obratno, s obzirom da spirala grejača (G) povlači ventil (V) unazad. Konstrukcija podsklopa grejača nepokretnog (Sng), sastavljene od cilindara (C), rastegnute spirale grejača (G) i krajnjih držača (D), i podsklopa filtarskog uzemljivača (Sfu), sastavljenog od nerastegnute provodne spirale, zatvorene na jednom kraju, a drugim navijene u otvor držača (D), upotpunjuju varijantna rešenja pronalaska.
Patent BE-820139-A (BE)
Title: Scaffolding for supporting shuttering for concrete - has vertical pillars supporting horizontal elements
IPC: E04G11/48
Filed: 1974-09-20
Abstract: The shuttering elements support concrete for a floor or roof; primary horizontal beams are fastened to the vertical pillars to support the loads imposed on the shuttering elements, these horizontal beams lying parallel to each other. Each pillar has a fixed head at the top and a sliding head underneath, which can be brought up to lift the shuttering assemblies into place. The shuttering assemblies are rectangular with a pillar at each corner, and primary and secondary horizontal beams lie at 90 deg. to each other, the secondary beams being supported by the primary beams.
Patent BE-898985-A (BE)
Title: Procede pour la fixation de composes du soufre et additifs pour la mise en oeuvre de ce procede
Inventor: POLLMANN S
IPC: F23J7/00
Filed: 1984-02-22
Abstract: Pour la fixation de composés du soufre, qui se forment en tant que produits de réaction lors de la combustion de combustibles renfermant du soufre dans un foyer, par adjonction d'additifs, on utilise comme additifs un mélange d'un carbonate alcalin et d'un oxyde alcalino-terreux, par exemple un mélange de carbonate de sodium et d'oxyde de magnésium.
Patent BE-900457-A (BE)
Title: Procede de preparation de plasmide vecteur de clonage et plasmides ainsi obtenus.
IPC: C12N15/74
Filed: 1984-08-29
Abstract: Procédé de préparation d'un plasmide vecteur, caractérisé en ce qu'il comprend l'extraction d'un plasmide d'ADN cryptique à partir d'une souche de T. ferrooxidans, le clivage du plasmide de T.ferrooxidans et d'un second plasmide qui contient un gène de résistance au chloramphénicol à l'aide de la meme enzyme de restriction, et la liaison des plasmides pour former un plasmide de recombinaison.
Patent BE-901001-A (BE)
Title: Dispositif pour le depot electrolytique d'une couche d'un metal de recouvrement sur une bande metallique.
Inventor: MOORE J-P
IPC: C25D5/08
Filed: 1984-11-07
Abstract: Dispositif pour le dépot électrolytique d'une couche d'un métal de recouvrement sur au moins une des deux faces d'une bande métallique (3) se déplaçant à travers un bain électrolytique (2), comprenant au moins un rouleau conducteur creux (4, 5) coopérant avec une amenée de courant cathodique (13) s'étendant transversalement par rapport à la direction de déplacement de la bande et tournant autour de son awe, en contact avec la bande sensiblement à la meme vitesse circonférentielle que la vitesse de translation de cette dernière, au moins une anode étant prévue dans le bain électrolytique (2), en regard d'au moins une des faces de la bande (3) traversant ledit bain, l'amenée de courant cathodique comprend une série de contacts (13) montés en parallèle et repartis sur la surface cylindrique intérieure du rouleau.
Patent BE-902529-A (BE)
Title: Chewing-gum non calorique non cariogene.
IPC: A23G4/06
Filed: 1985-05-29
Abstract: Chewing-gum non cariogène, non calorique qui ne contient pas de matrice de sucre et qui comprend sur base pondérale, 92 à 99% d'un gomme de base, jusqu'à 3% d'aromatisants et jusqu'à 4% de glycérol. Outre les avantages diététiques, ce chewinggum offre l'intéressante particularité que son adhérence est sensiblement nulle aux dents et en particulier aux prothèses dentaires. Il peut etre fabriqué au moyen de gommes de base de composition variées.
Patent CA-1051145-A (CA)
Title: Method for producing wire-insulating-lacquer resins preferably suitable for application in the molten condition
Inventor: SCHADE GERHARD
IPC: C09D179/08
Filed: 1974-02-28
Granted: 1979-03-20
Abstract: ABSTRACT OF THE DISCLOSURE           The prevent invention relates to a process for the production of  a synthetic resin  suitable for use in the production of insulating lacquer coatings on wires, and the insulated conductors produced therefrom.  It comprises re-esterifying dimethyl terephthalate with tris-(hydroxyethyl)-iso-cyanurate, esterifying the re-esterification  product thus obtained with an anhydride of a polybasic  aromatic carboxylic acid contain-ing three or more carboxyl groups to yield product containing car-boxyl groups, stopping the esterification by adding, a diprimary amins and effecting polycondensation of the estorification product and the diamins until the resin being formed has a consistency which, at 140 to 160°C renders it suitable for application to a substrate from the malt, which process is carried out in the presence of from 0.3 to 1.5% by weight, based on the weight of all monomers which are incorporated in the resin, of an alcoholate of titanium and/or vanadium and/or zirconium added to the re-esterification reaction mixture.
Patent CA-1046829-A (CA)
Inventor: BUSCH WALTER
IPC: G03G5/02
Filed: 1974-12-06
Granted: 1979-01-23
Abstract: Abstract of the Disclosure This invention relates to an electrophotographic copying material for recording high-energy radiation images, which comprises a carrier having thereon an optically homogeneous, electrically con-ductive layer having a surface resistance not exceeding 1010 ohms, which layer has thereon an optically homogeneous photoconductive layer including an organic photoconductor, the copying material also including at least one high-energy radiation-amplifying layer separable from the combination of the carrier, the conductive layer and the photoconductive layer. The invention also relates to a process for the electrophotographic production of a high-energy radiation Image using the novel copying material.
Patent CA-1057393-A (CA)
Inventor: SATO NOBUAKI
IPC: G11B20/02
Filed: 1975-04-07
Granted: 1979-06-26
Abstract: ABSTRACT OF THE DISCLOSURE: One field interval of a composite color television signal is recorded on one recording track Or successive recording tracks which extend parallel to one another on a record medium such as a magnetic tape. During the reproduction of color television signals in a conventional VTR (video tape recorder), successive color television signals are reproduced from the successive record tracks by means of two signal reproducing heads which are switched alternately. A color video signal reproducing circuit has an automatic gain control circuit for controlling the output level thereof and a muting circuit by which an operation of the automatic gain control circuit is rested during the joint portion between each field of the video signals so as to prevent a color flicker from being appeared on a monitor television regardless of timing axis variations caused by undesirable jitter components produced by the speed relation between the tape transportation and the head rotation in the VTR.
Patent CA-1043816-A (CA)
Title: METHOD FOR THE PRODUCTION OF .beta.-NAPHTHOL
Inventor: TAKAHASHI MASAAKI
IPC: C07C7/14
Filed: 1975-04-14
Granted: 1978-12-05
Abstract: ABSTRACT OF THE DISCLOSURE:          .beta.-Naphthol can be produced in high yields by allowing propylene and naphthalene to contact each other for a period of from 0.05 to 5.0 hours at a temperature in the range of from 230 to 350°C under a pressure of from atmospheric pressure to 50 kg/cm2 G. in the presence of a catalyst, adding to the resul-tant .alpha.-isomer-containing .beta.-monoisopropyl naphthalene a specific solvent about 0.5 to about 10 times as great by weight to produce a mixture, cooling the mixture in conjunction with seed cystals added thereto to a temperature in the range of from -20°C to about -30°C thereby causing the .beta.-monoisopropyl naphthalene to crystallize out, subsequently separating the solid from the liquid at the existing crystallizing temperature and having the isopropyl group of the resultant high-purity .beta.-monoisopropyl naphthalene substituted with a hydroxyl group by oxidizing the high-purity .beta.-monoisopropyl naphthalene and subsequently decomposing the resultant hydroperoxide in an acidic state.  The solvent mentioned above is a compound having properties such that it forms no azeotrope with monoisopropyl naphthalene and shows a solidifying point which is lower than the eutectic point for .alpha.-monoisopropyl naphthalene and .beta.-monoisopropyl naphthalene and the mixture result ing from the addition of the compound to monoisopropyl naphthalene at all times shows a viscosity which is lower than that of mono-isopropyl naphthalene.  This compound is also possessed of a polar group.
Patent CA-1038201-A (CA)
Inventor: UPDEGRAVE WALTER C
IPC: F16H1/28
Filed: 1975-04-25
Granted: 1978-09-12
Abstract: ABSTRACT         A planetary drive system especially useful in the transmission of high torques is disclosed.  An internal ring gear is fixed to a base on which a rotator is mounted.  A plurality of planet gears mounted on the rotator engage the ring gear.  A driven sun gear imparts translational motion to the planet gears relative to the fixed ring gear, thereby driving the rotator.  The planet gears and sun gear are mounted to permit radial movement with respect to the ring gear so that the sun gear and planet gears are self-centering, and lack of perfect roundness of the ring gear can be accommodated.
Patent CA-1050765-A (CA)
Inventor: HARTWIG JUERGEN
IPC: C21B13/14
Filed: 1975-05-22
Granted: 1979-03-20
Abstract: ABSTRACT   A method is provided for producing steel from iron oxide-containing raw materials.  The raw materials are initially converted in a reduction furnace by direct reduction with a reducing gas, to a substantially metallized sponge iron.  The metallized sponge iron is then melted with the addition of additives and possibly fine scrap in a melting vessel filled with a metal melt.  Heat and carbon monoxide-containing exhaust gases are formed in the melting vessel due to the reaction of oxygen-containing gases with carbona-ceous material.  The heat is utilized in part to melt the sponge iron and the exhaust gases are utilized for the direct reduction   The melt is then transferred to a further vessel where it is further processed into steel by means of suitable metallurgical measures.  In the process, the entire, strongly-heated exhaust gas from the melting vessel is caused to react in a reactor with (1) carbonaceous material, and with (2) water vapor and/or car-bon dioxide.  After suitable conditioning, this exhaust gas is utilized for the direct reduction of the iron oxide-containing raw materials.  An exhaust gas is formed in the direct reduction furnace during the direct reduction, and part of this exhaust gas is conducted through a gas processing system and combined with the conditioned exhaust gas from the melting vessel to form the reducing gas used in the direct reduction furnace.
Patent CA-1046551-A (CA)
Inventor: STAATS HENRY N
IPC: B42D3/00
Filed: 1975-06-16
Granted: 1979-01-16
Abstract: ABSTRACT          A binding for a plurality of sheets of paper comprises a back spine having a thermally activatable cement to secure the plurality of loose sheets in the binding, a transparent front cover attached by a pressure sensitive adhesive to a front flap integral with the back spine and a back cover which is either integral with the back spine or attached by a pressure sensitive adhesive to a back flap which is integral with the back spine.
Patent CA-1053663-A (CA)
Inventor: MAKOVEC FRANCESCO
IPC: C07D209/28
Filed: 1975-07-11
Granted: 1979-05-01
Abstract: ABSTRACT    Anti-inflammatory antirheumatic compounds having the formula:                                                     (A) wherein n1 and n2 are 2 or 3, are prepared by reacting 5-methoxy-2-methyl-3-indolyl acetic acid with an N-hydroxyalkyl-N'-chloroalkyl-piperazine in an organic solvent in the presence of a condensation agent, to obtain the corresponding N'-(2 or 3)-chloroalkyl-N-(2 or 3)-(5-methoxy-2-methyl-3-indoleacetoxy)-alkyl-piperazine, amidating the N-atom in the indole group in the resulting compound by means of p-chloro-benzoyl chloride to obtain the corresponding N'-(2 or 3)-chloroalkyl-N-(2 or 3)-[1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetoxy]-alkyl-piperazine and reacting the latter compound with N-benzoyl-N',N'-di-n-propyl-DL-isoglutamine in an organic solvent in the presence of a stoichiometric amount of sodium bicarbonate.
Patent CA-1057313-A (CA)
Inventor: KESSEN GUNTHER
IPC: C07C29/17
Filed: 1975-07-31
Granted: 1979-06-26
Abstract: PROCESS FOR THE CONTINUOUS PRODUCTION OF     Abstract of the Disclosure An improvement in a process for preparing 2-ethyl hexanol wherein:         A)  One mole of n-butyraldehyde is condensed with another mole of n-butyraldehyde in a condensation zone in the presence of an alkali metal hydroxide wherein there is . formed 2-ethyl hexenal and higher condensation products;         B)  The resultant product is contacted with water to separate alkali metal salts therefrom, an organic phase comprising 2-ethyl hexenal and higher condensation products is separated therefrom and unused alkali metal hydroxide is recycled to the condensation zone;         C)  The organic phase is separated in a separation zone into a 2-ethyl hexenal rich fraction and a residual fraction having a major amount of higher condensation product;       D)  The 2-ethyl hexenal rich fraction is introduced into a hydrogenation zone containing hydrogen and a hydrogen-ation catalyst and therein hydrogenated to 2-ethyl hexanol, the improvement residing in recycling to the condensation zone at least a portion of the residual fraction containing the major amount of higher condensation product.
Patent CA-1042749-A (CA)
Inventor: WITTY MICHAEL E
IPC: B01L99/00
Filed: 1975-08-12
Granted: 1978-11-21
Abstract: CONTROLLED DEPTH ASPIRATION CANNULA    Michael E. Witty Abstract of the Disclosure A controlled depth fluid aspiration cannula is disclosed comprising an elongated tubular member terminating at the distal end with a wall and terminating at the proximal end with attachment means to provide a sealing fitment for a flexible conduit. Radially disposed orifices are positioned near the digital end, and a radially extending flange is positioned between the ends of the tubular member to provide controlled depth aspiration of fluid.
Patent CA-1074331-A (CA)
Inventor: KOSLOWSKY LADISLAV
IPC: C11B3/00
Filed: 1975-09-10
Granted: 1980-03-25
Abstract: ABSTRACT  OF  DISCLOSURE        Separation of an edible oil into liquid and solid fractions. The edible oil is dissolved in about 0.5-4 parts by weight of a solvent being a C2-C3 alkanol containing about 2 to 10% by weight of water and the solution is cooled to a temperature at which it separates into two liquid phases and a solid fraction crystallizes. The crystallized solid fraction floats in the upper liquid phase and is recovered therefrom. The liquid fraction of the oil is re-covered from the lower liquid phase.
Patent CA-1042058-A (CA)
Inventor: EVANS JOHN JR
IPC: H01J3/02
Filed: 1975-09-24
Granted: 1978-11-07
Abstract: CATHODE RAY TUBE GUN WITH ELLIPTICALLY APERTURED GRIDS               Abstract An in-line electron gun, for generating and directing a plurality of electron beams along co-planar paths through a color selection electrode to the screen of a cathode-ray tube, includes a plurality of in-line cathodes and a plurality of aligned apertured grids be-tween the cathodes and the color selection electrode.          The two grids nearest the cathodes have vertically ellip-tical apertures therein, with the elliptical apertures aligned with one of the electron beam paths having an elliptical shape different from the shapes of the other elliptical apertures in the two grids.
Patent CA-1044321-A (CA)
Inventor: CAPEK WILLIAM J
IPC: F02P17/00
Filed: 1975-12-12
Granted: 1978-12-12
Abstract: ABSTRACT OF THE DISCLOSURE        The disclosure describes an ignition system for an internal combustion engine fitted with a plurality of spark plugs. The engine rotates a distributor that includes a primary coil which induces voltages in a secondary coil The secondary coil voltages are sequentially distributed to the spark plug in order to operate the engine.  The engine is provided with a source of common potential, generally referred to as chassis ground. Improved apparatus for displaying the waveform of the voltage produced by the secondary coil includes an oscilloscope having a first input and a second input. A conductive probe is positioned close to the secondary coil, and a single conductor operatively connects the probe to the first input of the oscilloscope A second conductor operatively connects the second input of the oscilloscope to chasses ground so that the waveform of the voltage produced by the secondary coil is displayed on the oscilloscope.
Patent CA-1056725-A (CA)
Inventor: BAUDE FREDERICK JOHN
IPC: B65G67/12
Filed: 1976-01-28
Granted: 1979-06-19
Abstract: ABSTRACT OF THE DISCLOSURE     2-Alkoxyimino-N-carbamoyl-2-cyanoacetamides are unstable in the presence Or bases, even bases which are quite weak.  Fungicidal compositions of these compounds are stabilized by the addition of an acidulant.
Patent CA-1062850-A (CA)
Inventor: BIRANOWSKI JEROME B
IPC: C08J9/00
Filed: 1976-02-20
Granted: 1979-09-18
Abstract: THERMALLY STABLE, RIGID, CELLULAR                 ISOCYANURATE POLYURETHANE FOAMS                      ABSTRACT OF THE DISCLOSURE          Rigid isocyanurate urethane polymers useful for insulation purposes and characterized by unexpected and significantly superior thermal stability are achieved by incorporation therein of 2,3-dibromo-2-butene-1,4-diol, antimony oxide and hydrated alumina.