baber/WOPTO huggingface dataset:
Patent NZ-515993-A (NZ)
Title: DNA vaccines for pets and sport animals
Inventor: FISCHER LAURENT JEAN-CHARLES
IPC: A61K39/205
Filed: 2000-06-08
Abstract: A DNA vaccine is describes which improves the efficacy and protection induced by DNA vaccination against viruses of the family of Paramyxoviridae and against the herpes virus, in pets and sport animals. The improvement of DNA vaccination is achieved either by formulating the vaccine with a cationic lipid containing a quaternary ammonium salt, DMRIE, or by modifications in the nucleotide sequence coding for the antigen of interest in particular of deletions of the fragment of the nucleotide sequence coding for the transmembrane domain of the antigen of interest, and/or insertions of introns and/or insertions of nucleotide sequences coding for the signal peptides, or by adding GM-CSF, or by combinations thereof. The immunogen used in the vaccine is derived from canine distemper virus (CDV), kennel cough (parainfluenza-2 or CPI-2), canine herpes virus (CHV-1) and equine herpes virus type 1 and type 4 (EHV-1 and EHV-4).
Patent NZ-516487-A (NZ)
Title: Identification polypeptides and nucleotide sequences from an animal virus vector that bind plant-infecting viruses
Inventor: DEMEDEIROS RICARDO B
IPC: C12Q1/70
Filed: 2000-08-07
Abstract: Disclosed is a method for identifying virus-binding polypeptides (putative viral receptors) and the nucleotide sequences encoding them. The method uses a cDNA expression library made from the total mRNA of an animal virus vector and a freshly purified preparation of a plant-infecting virus. Also disclosed are polypeptides identified from the western flower thrips that bind to the tomato spotted wilt virus.
Patent NZ-518414-A (NZ)
Title: Hand-held surgical instruments that access interior body regions
Inventor: REILEY MARK A
IPC: A61B17/34
Filed: 2000-10-13
Abstract: A composite instrument (10) is provided comprising a first functional instrument (20) and a second functional instrument (40) when the first functional instrument (20) is coupled with the second functional instrument (40). A composite handle (12) for the composite instrument is provided comprising a first handle (22) and a second handle (42) when the first handle (22) is coupled with the second handle (42). The handle (12) makes possible the reliable transmission, with increased mechanical advantage, of both torsional and longitudinal loads by the physician to the composite instrument, while resisting relative rotation between the first and second instruments (20, 40). The instrument is sterilization sensitive, changing physical appearance after sterilization.
Patent NZ-518831-A (NZ)
Title: Shaped body comprising an amphiphilic outer phase and a lipophilic inner phase
Inventor: ROGASCH RAINER
IPC: B29C48/05
Filed: 2000-10-13
Abstract: A   solid  shaped  body  dosage  form  for  medicinal administration  purposes,  having  a  length  up  to  100mm, comprising   40%wt   of  a  poloxamer  as   an   amphiphilic continuous  phase and 50%wt of a lipophilic component  as  a disperse phase, and a pharmaceutically effective active.
Patent NZ-524619-A (NZ)
Title: Competitive rewards benchmarking system and method
Inventor: ZITANER ERIC
IPC: G06Q10/06
Filed: 2001-08-22
Abstract: A competitive rewards database system comprises: a computer database for storing a collection of records comprising a competitive rewards data contributed by a plurality of different entities, the database maintained on a storage medium accessible by each of the entities a plurality of member computer systems, each associated with one of the entities and coupled to the database via a data feed to support the communication of competitive rewards data of that entity to the database, wherein the computer database, responsive to a determination that a portion of the competitive rewards data received via the data feed from one of the member computer system comprises an entity specific raw data format that is not compatible with a database format for the database, is operable to use mapping data to convert the portion of the competitive rewards data having the raw data format to the database format and wherein the computer database, responsive to a request transmitted electronically by one of the members, is operable to process a plurality of the records to complete an analysis of the competitive rewards data associated with one or more of the members.
Patent NZ-525694-A (NZ)
Title: Identity-based distributed computing for device resources
Inventor: ALLES DAVID
IPC: G06F3/12
Filed: 2003-05-06
Abstract: A system comprises a first device associated with at least one identity and includes a first resource and is configured to provide access to the first resource by at least one other device associated with the identity with the first computing device provides information about the first resource according to a resource schema associated with the at least one identity and a second device configured to request access to the first resource and performing a computing task including using the first resource on the first device to perform at least part of the task.
Patent NZ-530782-A (NZ)
Title: Aminoisoxazole derivatives active as kinase inhibitors
Inventor: CAVICCHIOLI MARCELLO
IPC: C07D413/14
Filed: 2002-07-29
Abstract: Disclosed are aminoisoxazole derivatives of formula (I); wherein, R is an optionally substituted 5 or 6 membered heteroaryl group with from 1 to 3 heteroatoms selected among nitrogen, oxygen and sulfur, optionally further condensed with a 5 to 7 membered aromatic or non-aromatic carbocycle or heterocycle with from 1 to 3 heteroatoms selected among nitrogen, oxygen and sulfur; X is a divalent group selected from -N(R3)- and -O-; Y is a divalent group selected from -CH(R3), -CO-, -CONH- and -SO2-, or Y may also be a single bond when R is a hydrogen atom or a C cycloalkyl group; Further disclosed are: the use of compounds of formula (I) in the manufacture of a medicament for the treatment of diseases caused by and/or associated with an altered protein kinase activity in a mammal in need thereof; for example the disease is a cell proliferative disorder selected from the group consisting of cancer, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; and processes for their production.
Patent NZ-533811-A (NZ)
Title: Method of treatment of gastrointestinal disease and polymeric composition for use therein
Inventor: MELROSE GRAHAM JOHN HAMILTON
IPC: A61P1/00
Filed: 2003-01-17
Abstract: The use of a polymer comprising a derivative of poly(2-propenal, 2-propenoic acid) in the manufacture of a medicament for the treatment or prophylaxis of gastrointestinal disease in an animal is described. The derivative is formed by reaction between poly(2-propenal, 2-propenoic acid) and an organic compound containing one or more hydroxyl groups to form protected carbonyl groups.
Patent NZ-538022-A (NZ)
Title: A method of culturing pearls stimulated by nacre-originating proteins
Inventor: WAN ROBERT
IPC: A01K61/00
Filed: 2003-07-10
Abstract: The invention relates to a pearl culture method employing a recipient pearl-producing mollusc with a gonad. The inventive method consists in introducing a nucleus and a stimulant solution containing proteins and associated molecules of mother-of-pearl origin into the gonad of the pearl-producing mollusc.
Patent NZ-540062-A (NZ)
Title: An improved evaporator for a heat pump water heater
Inventor: ISLAM RAFIQUL
Filed: 2005-05-13
Abstract: An evaporator panel used in a heat pump water heater having an inlet and an outlet and at least one channel therebetween, said at least one channel traversing across said panel in a serpentine fashion, said panel including at least one aperture through said panel adjacent said at least one channel; including the method of making the evaporator plate.
Patent NZ-541823-A (NZ)
Title: Substituted N-aryl heterocycles, method for production and uses thereof as medicaments
Inventor: SCHWINK LOTHAR
IPC: C07D401/12
Filed: 2004-02-13
Abstract: Disclosed is a compound of formula I, wherein the substituents are as defined in the specification. The compounds have MCH-receptor antagonistic activity and are useful in the treatment of obesity and type II diabetes.
Patent NZ-542603-A (NZ)
Title: Synthesis of 2-chloromethyl-6-methylbenzoic acid esters
Inventor: MAIER CLAUS-JURGEN
IPC: C07D263/32
Filed: 2004-03-12
Abstract: Disclosed are 2-Haloalkyl benzoic acid derivatives of formula (I), methods of their production and use in the synthesis of PPAR agonists.
Patent NZ-547754-A (NZ)
Title: Packaging bag with a detachable gusset and a reclosable opening, and production machine and method
Inventor: DOUE PHILIPPE
IPC: B65D85/07
Filed: 2004-12-03
Abstract: A packaging bag 10 comprises at least one flap 24 formed at one end with the flap 24 folded back along a fold line 22 against a face of the bag body and held in this position by a detachable connecting element 32, and a recloseable closure element 50 which extends transversally to the fold line 22 along at least a substantial length of the bag body and along a full height of the flap 24.
Patent NZ-549746-A (NZ)
Title: Building assembly component consisting of an elongate cladding support member with a H shaped cross section
Inventor: TURCO ANGELO MICHAEL
IPC: E04D3/366
Filed: 2005-02-10
Abstract: This discloses a jointing system for supporting a plurality of cladding panels 10 relative to a building or building frame 11 where the panels 10 have slots 18 extending along the edges. The jointing system includes an elongate support member 40 substantially H shaped in cross-section and having a longer inner flange for fastening to the building or building frame 11, the inner flange being connected by a web to a shorter outer flange to form an elongate recess 30 on each side of the web for receiving sealing means therein, whereby when a cladding panel 10 is supported relative to the building or building frame 11 by the jointing system, the outer flange is received in the slot 18 along the edge of the cladding panel 10 and the sealing means cooperates with the panel 10 to substantially seal the space behind the cladding panel 10 against the ingress of moisture.
Patent NZ-549898-A (NZ)
Title: Optimized expression of HPV 52 L1 in yeast
Inventor: BRYAN JANINE T
IPC: C07K14/025
Filed: 2005-03-18
Abstract: Disclosed are synthetic DNA molecules encoding modified variants of the human papillomavirus protein HPV52 L1. Specifically, the present disclosure provides polynucleotides encoding HPV 52 L1 protein, wherein said polynucleotides are codon-optimized for high level expression in a yeast cell. Further disclosed are synthetic nucleotide molecules that are altered to eliminate transcription termination signals that are recognized by yeast. The synthetic molecules may be used to produce HPV52 virus-like particles (VLPs), and to produce vaccines and pharmaceutical compositions comprising the HPV52 VLPs. The vaccines of the present invention provide effective immunoprophylaxis against papillomavirus infection through neutralizing antibody and cell-mediated immunity and may also be useful for treatment of existing HPV infections.
Patent NZ-550043-A (NZ)
Title: A switched mode power supply and method of production
Inventor: HARRISON MICHAEL JOHN
Filed: 2006-09-21
Abstract: A switched mode power supply, allowing a half bridge converter to be used alone or in combination with another converter to form a full bridge converter, is disclosed. A common controller may be used for either half bridge or full bridge configurations. The modular approach simplifies design for a range of power supplies and reduces costs.
Patent NZ-551443-A (NZ)
Title: Chimeric adenoviruses for use in cancer treatment
Inventor: HARDEN PAUL
IPC: C12N7/00
Filed: 2005-05-24
Abstract: Provided is a recombinant chimeric adenovirus having a genome comprising an E2B region, which said region comprises nucleic acid sequences derived from two different adenoviral serotypes, wherein the said chimeric adenovirus is oncolytic and demonstrates an enhanced therapeutic index for a tumor cell.
Patent NZ-555893-A (NZ)
Title: Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
Inventor: RUKER FLORIAN
IPC: C07K19/00
Filed: 2006-01-05
Abstract: Disclosed is an immunoglobulin constant domain or part thereof of human origin comprising at least one structural loop region of any of a CH1 domain, a CH2 domain, a CH3 domain, CH4 domain or a CL domain, said at least one structural loop region comprising at least one modification enabling a binding of said at least one modified loop region to an epitope of an antigen wherein the unmodified immunoglobulin constant domain does not bind to said epitope, wherein said modification excludes the incorporation of a pharmacologically active peptide of 2 to 40 amino acids into an Fc domain.
Patent NZ-560237-A (NZ)
Title: A quilt tool for mariner's compass star pattern
Inventor: WILLIAMS DEBRA JUNE
Filed: 2007-08-01
Abstract: A quilt tool is disclosed being a transparent plate having six guidelines 1 to 6, apertures 7, elongate apertures 8 and a central pivot aperture 9. Further details are disclosed.
Patent NZ-566688-A (NZ)
Title: A fishing line hauler and method of controlling
Inventor: SCHERER PHILLIP SHANE
Filed: 2008-03-13
Abstract: A method of determining a desired course for a fishing line hauler including a course determination module is provided. That method includes determining the desired course of the hauler by the course determination module, monitoring at least one of a current heading of the hauler and a current direction of travel of the hauler, and setting the desired course based on one of the current heading and the current direction of travel.
Patent NZ-574237-A (NZ)
Title: N'-cyano-n-halogenalkylimidamide derivatives
Inventor: JESCHKE PETER
IPC: A01N43/40
Filed: 2007-07-07
Abstract: Disclosed herein are N'-cyano-N-halogenalkylimidamide derivatives of formula (I) where substituents are as defined within the specification, process for their preparation and their uses for controlling animal pests especially arthropods, in particular insects. Also disclosed is a compound useful in the preparation of said derivatives.
Patent NZ-576769-A (NZ)
Title: Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs
Inventor: TARASOVA NADYA
IPC: A61K38/00
Filed: 2007-11-06
Abstract: Discloses a method for handling a hydrophobic agent comprising (a) combining in an aqueous solution (i) the hydrophobic agent and (ii) an isolated peptide that comprises at least 10 amino acids, and is a structural analog of a transmembrane domain of an integral membrane protein, wherein one terminus of the peptide has one or more consecutive negatively charged residues, and (b) allowing the peptide to self-assemble into nanoparticles, wherein the nanoparticles comprise the hydrophobic agent. Further disclosed are features of the claimed nanoparticle wherein (i) the isolated peptide may be a G-protein coupled receptor or an ABC transporter (ii) the isolated peptide comprises a further addition of a hydrophilic oligomer to the negatively charged terminus of the peptide (iii) the hydrophobic agent is an anticancer agent.
Patent NZ-577438-A (NZ)
Title: ([3-azabicyclo[3.1.0]hex-3-yl]alkoxy)benzamide derivatives
Inventor: CASARA PATRICK
IPC: A61K31/166
Filed: 2009-06-04
Abstract: Disclosed are ([3-azabicyclo[3.1.0]hex-3-yl]alkoxy)benzamide derivatives as represented by the general formula (I), wherein: ALK represents an alkylene chain; W represents a group selected from -N(R')C(=O)-R and -C(=O)N(R')-R; wherein R and R' represent, each independently of the other, a hydrogen or a linear or branched alkyl group optionally substituted by one or more groups selected from halogen, hydroxy and alkoxy. Of particular importance are the compounds N-(4-{3-[(1R,5S)-3-azabicyclo[3.1.0]hex-3-yl]propoxy}phenyl)-N-methylacetamide, N-(4-{2-[(1R,5S)-3-azabicyclo[3.1.0]hex-3-yl]ethoxy}phenyl)acetamide, N-(4-{2-[(1R,5S)-3-azabicyclo[3.1.0]hex-3-yl]ethoxy}phenyl)-2-methoxyacetamide, 4-{3-[(1R,5S)-3-azabicyclo[3.1.0]hex-3-yl]propoxy}benzamide, 4-{2-[(1R,5S)-3-azabicyclo[3.1.0]hex-3-yl]ethoxy}benzamide, N-(4-{3-[(1R,5S)-3-azabicyclo[3.1.0]hex-3-yl]propoxy}phenyl)-2-methoxy-acetamide and N-(4-{3-[(1R,5S)-3-azabicyclo[3.1.0]hex-3-yl]propoxy}phenyl)acetamide. Also disclosed are pharmaceutical compositions which comprise at least one compound as defined above, optionally in combination with one or more pharmaceutically acceptable excipients, for use in the treatment of cognitive and psycho-behavioural disorders associated with cerebral ageing, with neurodegenerative diseases or with cranial traumas and also in the treatment of mood disorders, of schizophrenia and of cognitive disorders associated therewith, of sleep disorders, of sleep-waking rhythm disorders, of attention-deficit hyperactivity syndrome or obesity.
Patent NZ-579634-A (NZ)
Title: A towing pin coupling with a head and a latch
Inventor: MERKEL ROBERT
IPC: B60D1/00
Filed: 2009-09-14
Abstract: A coupling 1 adapted for attachment to a towing pin 32 such as carried by a vehicle, comprises a head 3, a latch 7, a hinge to allow relative rotational movement between the head 3 and the latch 7 about a hinge axis, and means for causing the relative rotational movement between the head 3 and the latch 7. The head 3 and the latch 7 comprise portions that are substantially complementary to the towing pin 32, and are adapted for receipt of the towing pin 32 between the portion of the head 3 that is substantially complementary to the towing pin 32 and the portion of the latch 7 that is substantially complementary to the towing pin 32. The means for causing the relative rotational movement between the head 3 and the latch 7, comprise a camming slot 13 formed in the latch 7 and comprising at least one camming surface, and a cam pin 9 moveable against the at least one camming surface to move the latch 7 relative to the head 3.
Patent NZ-581174-A (NZ)
Title: Replikin peptides and uses thereof
Inventor: BOGOCH SAMUEL
IPC: A61P31/04
Filed: 2002-03-26
Abstract: Provided are methods of identifying an emerging strain of influenza virus for diagnostic, preventive or therapeutic purposes and of selecting an influenza virus peptide for inclusion in a preventive or therapeutic influenza virus vaccine comprising: (1) analysing virus sequences for the presence and concentration of Replikin sequences, (2) selecting at least one Replikin sequence present in the strain of influenza virus as an influenza peptide for inclusion in the influenza virus vaccine, wherein said at least one Replikin sequence comprises 7 to 50 amino acid residues comprising: (a) at least one lysine residue six to ten amino acid residues from another lysine residue; (b) at least one histidine residue; and (c) at least 6% lysine residues. Further provided are corresponding methods of producing and using vaccines based on Replikin peptides. (62) Divided Out of 569772
Patent NZ-581917-A (NZ)
Title: Macrocylces and their uses
Inventor: LAMARCHE MATTHEW J
IPC: A61K31/429
Filed: 2008-06-03
Abstract: Disclosed are macrocycle compounds of formula I or a pharmaceutically acceptable salt, enantiomer, stereoisomer, rotamer, tautomer, diastereomer, atropisomer, or racemate thereof, including a pyridine N-oxide thereof; wherein the substituents are as defined in the specification. Also disclosed is the use of these macrocyle compounds in treating bacterial infection such as Staphyloccocus aureus, Streptococcus pneumoniae, Mycobacterium tuberculosis, Enterococci, Clostridium difficile, Propionibacterium acnes, Bacteroides fagiles, Neisseria gonorrhoeae and Branhamella catarrhalis.
Patent NZ-583059-A (NZ)
Title: Method and product of making a polymer-binder composite
Inventor: BARNAT JAMES J
IPC: C08L95/00
Filed: 2008-07-21
Abstract: Disclosed is a method of making a polymer-binder composite comprising: feeding greater than 50 wt. percent of at least one polymer and at least one binder into a high shear device. .
Patent NZ-583284-A (NZ)
Title: Cyclic depsipeptides from isolated chondromyces crocatus useful as inhibitors of kallikrein 7 and human neutrophil elastase
Inventor: KRASTEL PHILIPP
IPC: A61K38/15
Filed: 2008-08-14
Abstract: Disclosed herein is a cyclic depsipeptide having the structure of formula (I), wherein an ester bond is formed between the carboxy group of A7 and the hydroxyl group of A2, wherein the acyl residue X is CH3CH2CH(CH3)CO or (CH3)2CHCO, A1 is glutamine, glutamic acid, or a derivative thereof, A2 is threonine,A3 is leucine, A4 is Ahp, 3-amino-piperidine-2-one, proline, 5-hydroxy-proline or a derivative thereof, A5 is isoleucine, A6 is tyroxine, N-Me-tyrosine or a derivative thereof, A7 is isoleucine or valine;or a pharmaceutically acceptable salt thereof. Also disclosed is the extraction of said compound from isolated Chondromyces microorganism from the strain Chrondromyces crocatus (DSM 19329) as well as an alternative process for its preparation.
Patent NZ-587270-A (NZ)
Title: Security screen frame with members having interengaging portions so as to be relatively pivotable so that a screen can be received between them
Inventor: MILLIGAN MARK JOHN
IPC: E06B3/16
Filed: 2009-01-14
Abstract: The present disclosure relates to a frame for a security screen. The frame includes two frame members which can be releasably interconnected to define a channel in which a screen sheet of the security screen can be received. The frame members define formations that enable the members to pivot relative to each other. In one embodiment, the frame members define other formations that enable the members to be releasably caught together during assembly, and a tool can be inserted between one of the members and the screen sheet to engage with one of the other formations so that the frame members can be released.
Patent NZ-592754-A (NZ)
Title: Use of high pressure processing to aid in the hair or feather removal from animal carcasses/hides
Inventor: CANNON JERRY EARL
IPC: A22B5/00
Filed: 2009-10-21
Abstract: A method of removing external carcass portions from an animal carcass, the method comprising placing an animal carcass in a high pressure processing vessel, subjecting the animal carcass to a pressure of greater than 50 MPa, wherein the external carcass portions are loosened from the carcass, removing the animal carcass from the high pressure processing vessel, and applying a force to the external carcass portions to remove the external carcass portions from the animal carcass.
Patent NZ-592891-A (NZ)
Title: Expression vector and methods of producing high levels of proteins
Inventor: SINGH ARUN K
IPC: C07K14/715
Filed: 2006-06-19
Abstract: Disclosed is a mammalian expression vector which comprises at least the following five regulatory elements: a CMV (Cytomegalovirus) promoter; an intron; TPL (Tripartite leader); V A (virus associated) genes; and a bovine growth hormone polyadenylation sequence.
Patent NZ-594003-A (NZ)
Title: Cancer biomarkers
Inventor: STONE STEVE
IPC: C12Q1/6886
Filed: 2010-01-07
Abstract: Provided is a method of classifying cancer comprising determining the expression of a panel of genes comprising (a) at least four cell cycle genes chosen from Panel F or (b) at least eight cell-cycle genes chosen from Table 2, or at least 75% of cell cycle genes from a specified list of genes, wherein increased expression of said cell-cycle genes indicates a poor prognosis.