baber/WOPTO huggingface dataset:
Patent NZ-578824-A (NZ)
Title: Predicting response to a her dimerisation inhibitor based on low her3 expression
Inventor: AMLER LUKAS C
IPC: C12Q1/68
Filed: 2008-02-29
Abstract: Disclosed is the use of a HER2 dimerization inhibitor antibody that binds to a heterodimeric binding site of HER2 in the manufacture of a medicament for treating a patient with ovarian, peritoneal, or fallopian tube cancer, wherein the patient's cancer has been determined to express HER3 at a level less than the median level for HER3 expression in the cancer type. Said HER2 dimerization inhibitor antibody can be pertuzumab.
Patent NZ-581110-A (NZ)
Title: Production of chemicals from pyrolysis oil
Inventor: MCCALL MICHAEL J
IPC: C10G21/02
Filed: 2008-06-11
Abstract: Disclosed is a process for producing chemical precursors from pyrolysis oil comprising partially deoxygenating the pyrolysis oil to produce an intermediate stream comprising aromatic compounds, oxygenates and water separating the intermediate stream into a first stream comprising a water-soluble phase and a second stream comprising aromatic compounds and concentrating the first stream by removing water, thereby creating a concentrated organic phase.
Patent NZ-581313-A (NZ)
Title: A method for filling a container with liquid and pressurising the container before sealing it
Inventor: MELROSE DAVID MURRAY
IPC: B65B31/04
Filed: 2010-11-17
Abstract: Disclosed is a method of filling a container with a fluid (40). The fluid is introduced through an opening of the container so that it at least substantially fills the container. A sealing chamber (84) then encloses the opening into the container. The pressure within the sealing chamber is increased by introducing at least one liquid and/or gas creating an increased pressure within the headspace (23b) of the container. A seal or cap (80) within the sealing chamber seals the opening of the container under the increased pressure conditions before the pressure within the sealing chamber is released. The pressurised container resulting from this method is capable of providing increased top-load capability, and the container can therefore be made more light-weight than a non-pressurised container for a given top-loading.
Patent NZ-587417-A (NZ)
Title: Mobile system for improving the picking and preliminary processing of apples, citrus, stone fruit and like objects
Inventor: BRYAN VINCENT E
IPC: A01D46/24
Filed: 2009-02-13
Abstract: A mobile fruit picking system comprising, in modular combination, a mobile vehicle chassis with wheels and a plurality of pneumatic tubes for transporting picked objects from tree height to an object decelerator means or water bath, a first conveyor means for transporting objects from the decelerator along a predetermined path of travel where a scanner scans the surface of the fruit with reject fruit diverted to a reject hopper, a second downloader conveyor receives objects from the first conveyor and transports the received objects to hopper then has means to load a storage bin or delivery point. The chassis can engage and reposition the storage bin.
Patent NZ-588632-A (NZ)
Title: Improved Fertiliser Compositions comprising acidulated phosphate together with a source of both water insoluble cobalt and water soluble cobalt
Inventor: BROWN MICHAEL WESLEY
IPC: C12P3/00
Filed: 2010-10-18
Abstract: Disclosed herein is a mixed release rate composition characterised in that the composition comprises an acidulated phosphate together with a source of both substantially water insoluble cobalt and substantially water soluble cobalt. Also disclosed is a method for manufacturing a mixed release profile composition for application to pasture land comprising the steps of: mixing a source of substantially water soluble cobalt and a suitable glue with a suitable solvent to create a substantially water soluble cobalt source-mixture; exposing an acidulated phosphate granule to the substantially water soluble cobalt source-solvent mixture; removing excess solvent; and applying a powdered mixture of a substantially water insoluble cobalt, a powdered adsorbent compound to the substantially water soluble cobalt coated acidulated phosphate to provide an outer coating layer thereon.
Patent NZ-590023-A (NZ)
Title: Apparatus and method to locate an object within a pipeline using one fixed and one mobile ultrasonic acoustic transmitter and receiver
Inventor: PAULSON PETER O
IPC: G01S11/14
Filed: 2009-06-25
Abstract: Apparatus for locating an object in a pipeline, comprising a transmitting station having means for transmitting in the pipeline acoustic emissions having a frequency in the range from 20 KHz to 200 KHz; a receiving station having a receiver capable of receiving the acoustic emissions transmitted by the transmitting station, one of the receiving station and the transmitting station being located at a known position on the pipeline and the other of the receiving station and the transmitting station being located on the object; clock means to determine the time taken for the acoustic emissions to travel between the transmitting station and the receiving station and recording means on both the transmitting station and the receiving station for recording acoustic emissions.
Patent NZ-591052-A (NZ)
Title: Antigen-presenting scaffolds
Inventor: BURN PAUL LESLIE
IPC: A61K39/00
Filed: 2009-08-04
Abstract: Disclosed is an antigen-presenting scaffold having a rigid structure for presenting antigens to the immune system, wherein the compound has the formula: Scaffold-[L-(Antigen)t]y Wherein the scaffold comprises a group: Core-[Spacer]z Wherein the Core is selected from an aryl or heteroaryl group, an acetylenyl or vinyl group, a caged hydrocarbon group or a caged silicon containing group, and the Spacer is a group wherein each Spacer, alone or in combination with the Core, comprises at least one partially conjugated unbranched or branched moiety comprising at least two groups selected from aryl,heteroaryl, alkenyl, acetylenyl and carbonyl, and wherein L is a linking group or covalent bond, and the other substituents are as described within the specification. Also disclosed is the use of said compound in the manufacture of a medicament for treating or preventing a cancer, infectious disease, autoimmune disease or disease characterised by immunodeficiency.
Patent NZ-598881-A (NZ)
Title: Crystalline anti-human il-12 antibodies
Inventor: KRAUSE HANS-JUERGEN
IPC: C07K16/00
Filed: 2008-03-27
Abstract: NZ 598881 Disclosed is a crystal of an anti-human IL-12 antibody wherein said crystal has a length of about 2-500 ?m.
Patent NZ-600374-A (NZ)
Title: High voltage direct current cable having an impregnated stratified insulation
Inventor: MARITANO MAURO
IPC: B32B27/10
Filed: 2009-12-16
Abstract: 600374 A high voltage direct current cable (1) comprising at least one fluid impregnated stratified insulation layer (4) is disclosed. The cable comprises at least one electrical conductor (2) and at least one semiconducting layer (3). The at least one stratified insulation layer is made from windings of at least one paper-polypropylene laminate. The at least one stratified insulation layer is impregnated with at least one electrically insulating fluid having a kinematic viscosity of at least 1,000 cSt at 60°C. The laminate includes at least one paper layer having an air impermeability of at least 100,000 Gurley sec-1. This high air impermeability of the paper layer(s) enables reduced swelling of the polypropylene layer(s) during impregnation with a high viscosity insulating fluid, thus preventing delamination.
Patent NZ-600697-A (NZ)
Title: Core drilling tools with retractably lockable driven latch mechanisms
Inventor: DRENTH CHRISTOPHER L
IPC: E21B25/10
Filed: 2010-12-16
Abstract: A core barrel assembly (110) having a driven latch mechanism (128). The driven latch mechanism can lock the core barrel assembly axially and rotationally relative to a drill string. The driven latch mechanism can include a plurality of wedge members (300) positioned on a plurality of driving surfaces (304). Rotation of the drill string can cause the plurality of wedge members to wedge between an inner diameter of the drill string and the plurality of driving surfaces, thereby rotationally locking the core barrel assembly relative to the drill string. The driven latch mechanism further includes a retracted groove (305) adapted to lock the plurality of wedge members radially within the core barrel assembly, thereby allowing for faster travel within the drill string.
Patent NZ-603682-A (NZ)
Title: Electrical connector assemblies and methods for forming and using the same
Inventor: BUKOVNIK RUDOLF ROBERT
IPC: H01R4/36
Filed: 2008-07-14
Abstract: 603682 Disclosed is a sealed electrical connector (100) for use with a conductor (5A). The electrical connector (100) comprises a housing defining a port (144), a conductive member (110) disposed in the housing and flowable sealant (162). The port (144) includes an entrance opening (144C), an exit opening (144D) and a conductor passage extending between and communicating with the entrance (144C) and exit (144D) openings. The conductor passage is adapted to receive the conductor (5A) therethrough. The flowable sealant (162) is disposed in the conductor passage. The sealant (162) is adapted to allow insertion of the conductor (5A) through the sealant (162) to the conductive member (110). The sealant (162) thus provides a seal about the inserted conductor (5A) and the conductive member (110) as the conductor passes through the conductor passage. The sealant (162) is positively pre-pressurised by the insertion of compression members (190), prior to insertion of the conductor (5A) into the sealant (162).
Patent NZ-605584-A (NZ)
Title: Strains of agrobacterium modified to increase plant transformation frequency
Inventor: MERLO DONALD J
IPC: C12N15/84
Filed: 2011-07-29
Abstract: Discloses a method for transforming a plant, comprising contacting a cell of the plant with an agrobacterium strain having at least one pTi helper plasmid comprising a 14.8 Kpnl fragment of pSB1 that is deficient in RecA function and a pTi plasmid having at least one disarmed T-DNA region, the T-DNA region comprising at least a right T-DNA border and exogenous DNA adjacent to the border, wherein the plasmids have differing origins of replication relative to each other. Also discloses the Agrobacterium and plant.
Patent NZ-606246-A (NZ)
Title: Anticancer derivatives, preparation thereof and therapeutic use thereof
Inventor: Commerçon Alain
IPC: C07D487/04
Filed: 2011-07-25
Abstract: Disclosed herein is a pyrrolo[1,4]benzodiazepine (PBD) dimers of formula I, wherein the variables are defined in the specification, a process for preparing a conjugate with said compound, and use of said compound for preparing a binding agent. Examples of the compound include 4-{ 2-[(2-[2-(2-methoxy-ethoxy)-ethoxyl-ethyI)-2-methyl-(2-methyl-2-mercapto-propyl)aminol-ethoxyl-2.6-bis-[(S)-2-eth-(E)-ylidene-7-dimethoxy-1,2,3,11a-tetrahydropyrrolo[2.1c][1.41]benzodiazepin-5-one-8-yloxymethyl]-pyridine, and N-hydroxysuccinimidyl 4-([2-(2.6-bis-[(S)-2-eth-(E)-ylidene-7-dimethoxy-1,2,3,11a-tetrahydropyrrolo[2.1c][1.41benzodiazepin-5-one-8-yloxymethyl]-pyridin-4-yloxy)-ethyl]-(3-{ 2-[2-(2-methoxy-ethoxy)-ethoxyl-ethoxyl-propionyl)-amino]-butanoate.
Patent NZ-608763-A (NZ)
Title: Unicondylar meniscal bearing knee replacement
Inventor: O’CONNOR JOHN
IPC: A61F2/38
Filed: 2011-08-31
Abstract: Disclosed is a kit of parts for use in a unicondylar meniscal bearing knee replacement. The kit of parts comprises a plurality of meniscal bearings (24). Each bearing (24) comprises a body with a dished first bearing surface on one side and a second surface on the opposite side of the body. Each bearing (24) in the kit of parts has an entrapment, being the maximum depth of the dished first surface, of between 3.2mm and 3.8mm. The range of entrapments are provided such that bearings of different thicknesses have approximately the same entrapments, as opposed to greatly varying the size of the entrapment to the size of the patient. This enables easier fitting in larger patients, prevents overstuffing of a smaller patient’s joint, reduces the chance of dislocation and subsequently reduces post-operative pain.
Patent NZ-612474-A (NZ)
Title: Method for operating a dirt stop surface, dirt stop surface unit and dirt stop surface assembled therefrom
Inventor: MAGONY RICHÁRD
IPC: B60S3/04
Filed: 2011-11-25
Abstract: A method for operating a dirt stop surface and a modular unit for the dirt stop surface are disclosed. The dirt stop surface (1) is divided into surface units (4) which dispense a fluid flow on the surface to be cleaned such as the sole of a shoe or a wheel passing over the dirt stop surface. The proximity of the surface to be cleaned is sensed separately for each surface unit (4) and the fluid is dispensed only by the surface units (3) near the surface to be cleaned.
Patent NZ-620935-A (NZ)
Title: Novel estrogen receptor ligands
Inventor: CHENG AIPING
IPC: C07D409/10
Filed: 2012-08-02
Abstract: Disclosed are biphenyl and terphenyl compounds of formula (I), wherein the substituents are as defined in the specification. Also disclosed is the use of compounds of formula (I) for treating as estrogen receptor ligands that are preferably selective for the estrogen receptor β isoform. The compounds are useful for the treatment of diseases related to the estrogen receptor such as depressive disorders, anxiety disorders, Alzheimer’s disease, cognitive disorders, osteoporosis, elevated blood triglyceride levels, atherosclerosis, endometriosis, urinary incontinence, autoimmune disease, and cancer of the lung, colon, breast, uterus and prostate. Examples of a compound of formula (I) are: 2-(3 ,5-dimethylisoxazol-4-yl)-N’,4’-dihydroxy-5-methyl-[1,1’-biphenyl]-3 -carboximidamide 2”-ethyl-N’,4-dihydroxy-5’-propyl-[1,1’:2’,1”-terphenyl]-3’-carboximidamide 2-(2,4-dimethylfuran-3-yl)-4’-hydroxy-5-propyl-[1,1’-biphenyl]-3-carbonitrile
Patent NZ-625830-A (NZ)
Title: Apparatus and method for downhole steam generation and enhanced oil recovery
Inventor: TESSIER LYNN P
IPC: E21B36/02
Filed: 2010-01-15
Abstract: A downhole steam generator for enhanced oil recovery from a hydrocarbon reservoir accessed by a cased and completed wellbore comprising: a burner assembly within the cased wellbore positioned at the hydrocarbon reservoir, the burner assembly having a downhole burner; a high temperature brush seal having a stack of a plurality of flexible brush rings (300), the brush seal being adapted for sealing a casing annulus between the downhole burner and the cased wellbore, each flexible brush ring comprising an annular ring having a multiplicity of circumferentially space, radially inwardly extending slits (350) which are rotationally indexed from one another to misalign slits of the adjacent annular ring; and means for injection of water into the hydrocarbon reservoir above the brush seal.
Patent NZ-625973-A (NZ)
Title: Influenza virus vaccines and uses thereof
Inventor: VOGELS RONALD
IPC: C07K14/005
Filed: 2012-11-27
Abstract: Discloses an influenza hemagglutinin stem domain polypeptide comprising (a) an H1 HA1 N-terminal segment comprising the amino acids 1-52, covalently linked by a linking sequence of 0-10 amino acid residues to an H1 5 HA1 C-terminal stem segment comprising the amino acids 321-end of HAl, and (b) an influenza hemagglutinin HA2 domain, wherein the C-terminal amino acid residue of the HA1 C-terminal stem segment is glutamine (Q), serine (S), threonine (T), asparagine (N), aspartic acid (D) or glutamic acid (E), and wherein one or more of the amino acids on position 406, 409, 413 and 416 have been changed into an amino acid selected from the group consisting of S,T,N,Q,R,H,K,D,E and G, and wherein the polypeptides comprise a disulphide bridge between the amino acids of position 324 and 436; wherein the polypeptide comprises hemagglutinin stem domains from HA of the influenza virus A/ Brisbane/59/2007(SEQ ID NO:1) or A/California/04/2009 (SEQ ID NO: 159), and wherein the numbering is based on the numbering of amino acids of the H1N1 influenza strain A/Brisbane/59/2007(SEQ ID NO:1); and an influenza hemagglutinin stem domain polypeptide comprising (a) an H3 HA1 N-terminal segment comprising the amino acids 1-61, covalently linked by a linking sequence of 0-10 amino acid residues to an H3 HA1 C-terminal stem segment comprising the amino acids 323-end of HA1, and (b) an influenza hemagglutinin HA2 domain wherein the C-terminal amino acid residue of the HA1 C-terminal stem segment is glutamine (Q), serine (S), threonine (T), asparagine (N), aspartic acid (D) or glutamic acid (E) and wherein one or more of the amino acids on position 40l, 408, 411, 415 and 418 have been changed into an amino acid selected from the group consisting of S,T,N,Q,R,H,K,D,E and G, and wherein the polypeptides comprise a disulphide bridge between the amino acids of position 326 and 438; wherein the polypeptide comprises HA domains of A/Wisconsin/67/2005 (SEQ ID NO: 89) or A/Hong Kong/1/1968 (SEQ ID NO: 121), and wherein the numbering is based on the numbering of amino acids of the H3N2 influenza strain A/Wisconsin/67/2005 (SEQ ID NO: 89); wherein the sequences are as defined in the complete specification.
Patent NZ-627068-A (NZ)
Title: E-selectin antagonist compounds, compositions, and methods of use
Inventor: MAGNANI JOHN L
IPC: C07H15/207
Filed: 2012-12-21
Abstract: Methods and compositions using E-selectin antagonists are provided for the treatment and prevention of diseases and disorders treatable by inhibiting binding of E-selectin to an E-selectin ligand. Described herein are E-selectin antagonists including, for example, glycomimetic compounds, antibodies, aptamers and peptides that are useful in methods for treatment of cancers, and treatment and prevention of metastasis, inhibiting infiltration of the cancer cells into bone marrow, reducing or inhibiting adhesion of the cancer cells to endothelial cells including cells in bone marrow, and inhibiting thrombus formation. These E-selection antagonists have the general formula (Ia) below.
Patent NZ-628122-A (NZ)
Title: Methods and systems for providing file data for a media file
Inventor: ROGERS SIMON DARRYL
IPC: H04N21/854
Filed: 2013-01-24
Abstract: A method of providing file data for a media file of a pre-determined format from a file system (31) comprising a file record database (33) and a data store (32), wherein the media file corresponds to a programme consisting of a plurality of segments, and wherein the segments included in the programme are dynamically determined. The method comprises the steps of receiving details of the programme including the duration of the programme, and determining the layout of the media file in the pre-determined format from the received details of the programme, the layout including locations for essence data within the file. A file record for the media file in the file record database (33) is then created. In response to a request for the location of essence data within the file, a location given by determined layout of the media file is returned. Further, in response to an instruction that a segment is to be included in the programme, essence data corresponding to the contents of the segment is obtained. Then, in response to a request for a portion of essence data from the media file corresponding to a time period of the programme, essence data derived from the received essence data according to the determined layout of the media file is returned.
Patent NZ-629829-A (NZ)
Title: Anti-c5a antibodies and methods for using the antibodies
Inventor: ZHANG YUCHUN
IPC: C07K16/18
Filed: 2011-04-29
Abstract: Disclosed is the use of an isolated or recombinant antibody, or antigen-binding fragment thereof, comprising a light chain CDR1 comprising the amino acid sequence RASESVDSYGNSFMH, a light chain CDR2 comprising the amino acid sequence RASNLES, a light chain CDR3 comprising the amino acid sequence QQSNEDPYT, a heavy chain CDR1 comprising the amino acid sequence DYSMD, a heavy chain CDR2 comprising the amino acid sequence AIHLNTGYTNYNQKFKG, and a heavy chain CDR3 comprising the amino acid sequence GFYDGYSPMDY, for the manufacture of a medicament for the treatment of a C5a-associated complement disorder.
Patent NZ-701849-A (NZ)
Title: Arylethynyl derivatives
Inventor: JAESCHKE GEORG
IPC: C07D209/52
Filed: 2013-07-12
Abstract: The present invention relates to ethynyl derivatives of formula (I) wherein R1 is phenyl, which is optionally substituted by 1-2 halogen atoms; selected from fluorine or chlorine; or to a pharmaceutically acceptable acid addition salt in enantiomerically pure form. It has been found that the compounds of general formula (I) are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
Patent NZ-702608-A (NZ)
Title: Separator device
Inventor: DOWNIE SIMON
IPC: F24D19/00
Filed: 2013-05-21
Abstract: A separator device for removing particles from suspension in a liquid comprises: a housing (12), having first (19) and second (40) chambers with apertures (98) for ingress and egress of liquid into the first chamber (19); means (100) for setting up a swirl of liquid within the first chamber (19); apertures enabling flow of liquid between the first chamber (19) and the second chamber (40); means for setting up a swirl of liquid within the second chamber (40), the swirl in the second chamber (40) being in substantially the opposite direction to the swirl in the first chamber, and there being no substantial flow in the second chamber (40) which is in the same direction as the swirl in the first chamber (19).
Patent NZ-705614-A (NZ)
Title: Reconfigurable workstation support
Inventor: SCHIAVELLO PETER PAUL
IPC: A47B21/06
Filed: 2010-06-28
Abstract: An articulated connector configured to join a pair of cable reticulation beams. The articulated connector including a multiplicity of cable retaining segments (390) defining channel segments, with hinges and flexible members (384) between adjacent cable retaining segments. The flexible members relatively flexible in one direction but relatively stiff in another.
Patent NZ-706772-A (NZ)
Title: Aggrecanase inhibitors
Inventor: DURHAM TIMOTHY
IPC: C07D233/76
Filed: 2013-10-18
Abstract: The present invention provides compounds having the formula: wherein R1 is selected from methyl, ethyl, propyl, cyclopropyl, and dimethyl, or a pharmaceutically acceptable salt thereof, along with methods and intermediates for their preparation, and uses thereof. The compounds inhibit aggrecanase. The compounds can be useful for treatment of arthritis and in particular, osteoarthritis, as well as inhibiting cartilage erosion.