baber/WOPTO huggingface dataset:
Patent CA-3118881-A1 (CA)
Title: Composition for preventing and treating transplant rejection or transplant rejection diseases, comprising novel compound and calcineurin inhibitor
Inventor: CHO MI-LA
IPC: A61K38/13
Filed: 2019-11-07
Abstract: The present invention relates to a composition for preventing and treating transplant rejection or transplant rejection diseases, the composition comprising a novel compound and a calcineurin inhibitor. A co-administration, of the present invention, with respect to an in vivo or in vitro syngeneic (allogenic) model, a transplant rejection disease model, a skin grafting model and a liver transplant patient, 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg, 3) has an effect of inhibiting side effects, such as tissue damage, occurring in a single administration, 4) inhibits various pathogenic pathways, 5) inhibits the death of inflammatory cells, and 6) increases the activity of mitochondria, and thus mitigates side effects possibly occurring in the single administration of conventional immunosuppressants, and inhibits transplant rejection. Thus, the present invention may be used in the field of pharmaceutics relating to transplant rejection or various immune disorders possibly occurring after transplantation.
Patent CA-3119230-A1 (CA)
Inventor: DENAYER IWEIN
IPC: C12Q1/22
Filed: 2019-11-19
Abstract: Holder suitable for holding one or more biological indicators and/or one or indicators and one or more thermocouples, characterised in that the holder (1) consists of one or more basic parts (2, 3a, 3b), being at least one first basic part (2) wherein one or more biological indicators and/or one or more thermocouples can be placed in the basic part (2), the basic part (2) being provided, at the location where the biological indicator or indicators can be located, with one or more holes (5), wherein the holder (1) is provided with means (11) for securing the one or more thermocouples and/or biological indicators in the holder (1) and wherein at least one of the one or more basic parts (2, 3a, 3b) is flexible.
Patent CA-3121892-A1 (CA)
Title: Universal tube stub plug with seal port
Inventor: LANTZ JOHN C
IPC: F16L41/02
Filed: 2019-12-17
Abstract: A fluid substrate comprising a manifold including a circular opening, a tube stub plug coupled with the manifold at the circular opening, wherein an anti -rotation feature prevents the tube stub plug from rotating with respect to the manifold.
Patent CA-3122441-A1 (CA)
Title: Induced cavitation mixing apparatus
Inventor: SEABROOK JAMES ANTHONY
IPC: C10G21/08
Filed: 2020-01-02
Abstract: A cavitation mixing apparatus is provided for performing separations from solid material using subcritical liquid CO2. A cavitation inducing device inside a cavitation mixing vessel is held in place with a cavitation mixer mount comprising at least one fluid channel for equalizing gaseous pressure of CO2 around the cavitation inducing device. Also described is method of separating oils from a crude plant oil mixture by injecting crude plant oil into a pressurized mixing vessel comprising liquid carbon dioxide and mixing the crude oil with the liquid carbon dioxide under pressure using powered induced cavitation, the cavitation mixing vessel comprising an encapsulated cavitation inducing device.
Patent CA-3123026-A1 (CA)
Inventor: SINGER MICHAEL
IPC: A61M1/34
Filed: 2019-12-18
Abstract: Systems and methods for estimating the post-treatment ultrafiltration rate of a patient are provided. A medical device can be configured to determine an estimated post-treatment ultrafiltration rate based on one or more values associated with a patient prepared to undergo treatment with the medical device. The medical device can also be configured to compare the estimated post-treatment ultrafiltration rate with one or more threshold values. The medical device can be configured to have an alert module, which can be activated when the estimated post-treatment ultrafiltration rate exceeds the one or more threshold values.
Patent CA-3123455-A1 (CA)
Title: Data migration across saas applications
Inventor: VAN ROTTERDAM JEROEN MATTIJS
IPC: G06F16/958
Filed: 2020-01-23
Abstract: A client computing device includes at least one display, an embedded browser that includes first and second browsers, a migration user interface (UI) control and a processor. The first browser is to access a page from a source application for display, and the second browser is to access a form from a target application for display. The processor cooperates with the embedded browser in response to a user selecting the migration UI control to extract data from the displayed page, analyze the extracted data to determine a context of the data, and analyze the displayed form for target form fields. A pattern matching algorithm matches at least a portion of the extracted data to the target form fields. The matched extracted data is migrated to the displayed form as target data values associated with the target form fields.
Patent CA-3128076-A1 (CA)
Inventor: SHEIKH DANIEL
IPC: G06F16/35
Filed: 2021-08-12
Abstract: Systems and methods for processing extracted data from different data sources to classify the data as an intent, a concern, and an insight for a client using an intent/concern engine. The system has a handler to route the data to a client domain, a financial product domain, a client insight domain and a client concern domain in some embodiments. The system can determine action or task recommendation based on the intent, concern, and insight for the client using a business rule system, and transmits the action or task recommendation to an advisor interface.
Patent CA-3129814-A1 (CA)
Inventor: KENT JOSEPH
IPC: A47J19/02
Filed: 2021-09-02
Abstract: A juicer includes a container with a spout and a central support pillar extending upwardly from a floor of the container. A strainer having a handle and a reamer is configured to be removably supported by the container and the central pillar. The strainer is mounted for rotation by grasping the handle and rotating the strainer with respect to the container so that juice expressed from a fruit will flow down the reamer to the strainer, with pulp being captured by the strainer while juice flows through the through-holes provided in the strainer and into the container.
Patent CA-3132189-A1 (CA)
Inventor: MASON DEREK
IPC: G16B20/20
Filed: 2020-04-08
Abstract: La présente invention concerne des systèmes et des procédés pour effectuer des prédictions en classant une ou plusieurs propriétés d'une protéine de liaison telle qu'un anticorps, par exemple, une affinité ou une spécificité d'un anticorps pour un antigène. Le système peut comprendre un ou plusieurs modèles d'apprentissage automatique qui peuvent extrapoler des relations complexes entre la séquence d'acides aminés et une fonction. Le système peut être entraîné sur des données d'apprentissage de haute qualité générées par un seul site en deux étapes et une approche de balayage de mutation profonde combinatoire. Les modèles entraînés peuvent ensuite effectuer des prédictions sur de nouvelles séquences variantes générées in silico. La présente invention concerne des séquences d'acides aminés générées par les systèmes et les procédés décrits, et des utilisations des séquences générées pour produire des protéines à usage thérapeutique et diagnostique.
Patent CA-3132197-A1 (CA)
Title: Rna-guided dna integration using tn7-like transposons
Inventor: STERNBERG SAMUEL HENRY
IPC: C12N15/63
Filed: 2020-03-06
Abstract: In certain embodiments, the present systems and methods use Tn7-like transposons that encode CRISPR-Cas systems for programmable, RNA-guided DNA integration. For example, the CRISPR-Cas machinery directs the Tn7 transposon-associated proteins to integrate DNA downstream of a target site (e.g., a genomic target site) recognized by a guide RNA (gRNA).
Patent CA-3135845-A1 (CA)
Title: Systemes de culture cellulaire et utilisations associees
Inventor: MURTHY SHASHI K
IPC: G16B20/00
Filed: 2020-04-02
Abstract: La présente invention concerne des systèmes de surveillance et de commande de culture cellulaire comprenant un appareil de culture cellulaire associé fonctionnellement à un dispositif de commande. Le dispositif de commande comprend un processeur matériel couplé à une mémoire contenant des instructions exécutables par le processeur pour amener le dispositif de commande à recevoir des données associées aux cellules devant être cultivées ; à se connecter à une ou plusieurs bases de données pour recevoir des données de protocole de culture cellulaire ; et à déterminer un protocole de culture cellulaire pour les cellules à cultiver. L'invention concerne également des procédés de détermination d'un protocole de culture cellulaire qui comprennent la réception de données associées aux cellules à cultiver ; la connexion à une ou plusieurs bases de données pour recevoir des données concernant des protocoles de culture cellulaire ; et la détermination d'un protocole de culture cellulaire pour les cellules à cultiver.
Patent CA-3135878-A1 (CA)
Inventor: SERATE DUANE GO
IPC: G01N29/04
Filed: 2021-10-26
Abstract: A degradation monitoring system and a method for monitoring degradation of equipment are provided. The monitoring system includes a plurality of sensors applied to a surface of an internal component of the equipment, the internal component being subjected to a fluid causing degradation to the internal component during use of the equipment, the sensors being provided using a low profile substrate. The system also includes an output cable coupled to the plurality of sensors and being fed from an interior of the equipment to an exterior of the equipment to carry the signals acquired by the plurality of sensors to the exterior of the equipment. The system also includes a data acquisition module positioned in the exterior of the equipment, the data acquisition module being connected to at least one computing device for receiving and processing the signals acquired by the plurality of sensors.
Patent CA-3136471-A1 (CA)
Inventor: LAGASSE ERIC
IPC: A61K45/00
Filed: 2020-04-10
Abstract: Provided herein are methods and systems of transplant cells and growing an ectopic tissue in a lymph node of a subject. In certain embodiments, the methods and systems provided herein enable minimally invasive cell transplantation to treat patients in need thereof. In certain embodiments, the methods and systems provided herein include the use of ultrasound endoscopy.
Patent CA-3137613-A1 (CA)
Title: Handle assemblies for hand-held surgical instruments
Inventor: NICHOLAS DAVID A
IPC: A61B17/00
Filed: 2021-11-04
Abstract: A handle assembly includes a single-motor transmission assembly for actuating various functions of an attached end effector.
Patent CA-3139874-A1 (CA)
Title: Two-way communication in a medical device
Inventor: PEAKE GREGORY ROBERT
IPC: A61M16/00
Filed: 2020-05-15
Abstract: A system for providing continuous positive air pressure therapy is provided. The system includes a flow generator, a sensor, and a computing device. The computing device is configured to control operation of the flow generator based on sensor data. The computing device is further configured to display, on a display device, one or more questions relating to demographic and/or subjective feedback; responsive to displaying the one or more questions, receive one or more inputs indicating answers to the one or more questions; transmit the answers to a remote processing system; receive, from the remote processing system, settings determined based on the transmitted answers; and adjust control settings of the system based on the received settings.
Patent CA-3144568-A1 (CA)
Title: Method and apparatus for renovation works on a building
Inventor: HOLLOWAY MATHEW
IPC: B05B13/04
Filed: 2020-06-24
Abstract: The present application provides a method for renovation works on a building that has a plurality of building elements, for example walls. The method includes: receiving scan data of a building element of the building; (150) processing the scan data to determine at least one dimension of the building element and an initial property of the building element from the scan data; configuring (160) a building system for the building element to achieve a target property of the building element, the building system being configured according to the at least one dimension of the building element and according to the initial property of the building element; and generating instruction data (170) for fabricating the building system. There is also provided an apparatus for renovation works on a building that has a plurality of building elements, for example walls.
Patent CA-3145304-A1 (CA)
Inventor: QIAO WEIHUA
IPC: H04W48/12
Filed: 2020-07-09
Abstract: Une fonction de gestion d'accès et de mobilité (AMF) d'un premier réseau mobile terrestre public (RMTP) reçoit des informations d'état provenant d'une première fonction de réseau. Les informations d'état comprennent une indication de sinistre de réseau et l'identifiant d'un second RMTP. L'indication de sinistre de réseau indique une défaillance du second RMTP dans une zone de couverture. Sur la base des informations d'état, l'AMF détermine au moins une station de base du premier RMTP. L'AMF envoie un message de configuration à la ou aux station(s) de base. Le message de configuration comprend les informations d'état.
Patent CA-3152947-A1 (CA)
Title: Compositions and methods for the detection of a chromosomal translocation in brassica napus
Inventor: CHARNE DAVID GEORGE
IPC: A01H5/00
Filed: 2020-09-24
Abstract: Provided are compositions and methods for the detection of a chromosomal location in Brassica napus. This disclosure is generally related to the field of plant molecular biology, and in particular embodiments, to the field of detecting a chromosomal translocation within plants. In certain embodiments, the chromosomal translocation occurs between the N7 and N16 chromosomes of Brassica napus. In other embodiments, the chromosomal translocation is a homoeologous chromosomal reciprocal translocation. Accordingly, this disclosure provides compositions and methods for the identification, detection and utilization of such a chromosomal translocation.
Patent CA-3158354-A1 (CA)
Inventor: CHICK STEVEN
IPC: G01D3/00
Filed: 2019-10-25
Abstract: A pressure testing system (10) includes a plurality of pressure sensors (16) and a user interface (14). Each pressure sensor (16) includes a housing (20), a pressure transducer (18) to measure pressure and convert the measured pressure to pressure data, a sensor storage module (76) containing a unique identifier of the pressure sensor (16), a sensor communications module (32) for transmitting identifier data and the pressure data, and a representation (19) of the unique identifier carried on an external surface of the housing (20). The user interface (14) includes an interface storage module (112) containing a library of the unique identifiers, an interface communications module (114) for receiving the transmitted identifier data and pressure data, and a controller (110) for identifying the selected pressure sensor (16) and for confirming that that pressure sensor (16) is associated with the user interface (14) by matching the unique identifiers.
Patent CA-3162122-A1 (CA)
Title: Oral care implement, handle thereof, and oral care refill head therefor
Inventor: JI YANMEI
IPC: A46B7/04
Filed: 2019-11-25
Abstract: An oral care implement (1000) includes a handle (100) and an oral care refill head (200). The oral care refill head (200) is alterable between a first state in which it is separated from the handle (100) and a second state in which it is coupled to the handle (100). The oral care refill head (200) has a proximal edge surface (222) that defines an opening (230) into a sleeve cavity (221). The proximal edge surface (222) is inclined with a radial distance from a cavity axis (B-B) of the sleeve cavity (221). Similarly, the handle (100) has a gripping portion (110) that terminates at a distal end (112) and a stem (120) that protrudes from the distal end (112). The annular shoulder surface (116) is inclined downwardly and away from a stem (120) to facilitate mating of the oral care refill head (200) to the handle (100). The oral care refill head (200) may have features for securing the oral care refill head (200) to the stem (120) of the handle (100).
Patent CA-3163174-A1 (CA)
Title: Ensemble de jeu
Inventor: GOULOIS JULIEN
IPC: A63F13/95
Filed: 2020-11-19
Abstract: L'invention concerne un ensemble de jeu comprenant au moins un module de jeu (1) comprenant un élément de jeu (2) et un socle (3) équipé d'une carte électronique (6) comprenant des moyens de communication; un lecteur électronique (7) comprenant des moyens (8a, 8b) de connexion à un terminal (9c) permettant d'accéder à au moins une plateforme informatique (10) de fourniture d'au moins un service (11), ledit lecteur étant agencé pour connecter le module de jeu (1) audit terminal par interaction avec les moyens de communication de la carte électronique (6), afin de pouvoir utiliser une fonctionnalité (2a) offerte par ledit élément de jeu dans le service (11) fourni par ladite plateforme informatique, le module de jeu (1) comprenant en outre une matrice sphérique (18) dans laquelle sont enrobés l'élément de jeu (2) et le socle (3), ladite matrice sphérique permettant d'utiliser ledit module de jeu comme une bille de jeu.
Patent CA-3163374-A1 (CA)
Inventor: SMAKMAN PIETER
IPC: A61F5/058
Filed: 2020-12-19
Abstract: La présente invention concerne une orthèse (1) destinée à être portée sur une main humaine (2) pour limiter le mouvement d'au moins l'articulation carpo-métacarpienne (CMCj) du pouce et de préférence également de l'articulation métacarpo-phalangienne (MCPj)) du pouce (2-1), l'orthèse (1) comprenant une section de métacarpe (3), qui, lorsque l'orthèse (1) est portée sur une main, s'étend de part et d'autre des métacarpes des doigts 2-5, et une section de pouce (4), ladite section étant incurvée ou annulaire et s'ajustant autour du pouce (2-1), de préférence autour de la phalange proximale (6) du pouce (2-1). La section de pouce (4) est reliée à la section de métacarpe (3) par l'intermédiaire d'une section métacarpienne du pouce (7) qui, lorsque l'orthèse (1) est portée sur une main (2), s'étend le long et/ou autour du métacarpe du pouce (8).
Patent CA-3163479-A1 (CA)
Title: Process for preparing amines over a copper catalyst
Inventor: ERNST MARTIN
IPC: C07C209/26
Filed: 2020-11-24
Abstract: A process for preparing an amine by reacting an aldehyde and/or ketone with a nitrogen compound selected from the group consisting of ammonia and primary and secondary amines, followed by hydrogenation of the resulting reaction product in the liquid phase and in the presence of hydrogen and a heterogeneous copper oxide hydrogenation catalyst at a temperature of 20 to 230°C, wherein the aldehyde and/or ketone is reacted with the nitrogen compound either together with the hydrogenation in the liquid phase and in the presence of hydrogen and of the catalyst (alternative 1) or in a step preceding the hydrogenation (alternative 2), and wherein the catalytically active composition of the catalyst, prior to reduction with hydrogen, contains at least 24% by weight of oxygen compounds of copper, calculated as Cu.
Patent CA-3164700-A1 (CA)
Inventor: MENEGOTTO JEROME
IPC: A61K9/16
Filed: 2021-01-29
Abstract: The present invention relates to an amorphous solid dispersion comprising ABX464 and at least one pharmaceutically acceptable carrier. The present invention also concerns a pharmaceutical composition comprising said ASD, processes for their preparation, an ASD obtainable by specific processes, their use as a medicament and more particularly their use in the treatment and?or prevention of inflammatory diseases, diseases caused by viruses and/or cancer or dysplasia.
Patent CA-3164704-A1 (CA)
Inventor: CABAHUG ERIC F
IPC: F41G11/00
Filed: 2020-01-17
Abstract: Une arme à feu comprend un récepteur inférieur stockant une source d'énergie électrique et un récepteur supérieur fixé au récepteur inférieur. Un dispositif à axe de pivot fournit un point de pivotement mécanique entre les récepteurs supérieur et inférieur et un transfert d'énergie électrique depuis la source d'énergie électrique dans le récepteur inférieur vers au moins un rail accessoire fixé au récepteur supérieur. Ledit rail accessoire comporte des contacts électriques qui viennent en prise avec des contacts correspondants sur un dispositif accessoire électronique pour fournir l'énergie électrique au dispositif accessoire électronique.
Patent CA-3165313-A1 (CA)
Title: Data hierarchy protocol for data transmission pathway selection
Inventor: TURNER PETER JAMES
IPC: H04W40/34
Filed: 2020-12-18
Abstract: A dataflow hierarchy protocol is implemented by one or more devices to optimize how the one or more devices process datagrams for network communications. The dataflow hierarchy considers various available network pathways for dataflow. A device implementing the dataflow hierarchy selects one or more of the available network pathways to provide low latency in data communication with other devices. The device may sample various available network pathways to determine pathway metrics (e.g., latency) and select one or more network pathways based on the metrics. The available network pathways can include pathways through one or more intermediary nodes, such as pathways through a game server, pathways through a cell tower, and pathways through a network.
Patent CA-3166301-A1 (CA)
Title: Plate-forme pour la chromatographie liquide native-spectrometrie de masse
Inventor: WANG SHUNHAI
IPC: G01N30/84
Filed: 2021-01-29
Abstract: L'invention concerne des systèmes de chromatographie liquide native-spectrométrie de masse et des méthodes d'utilisation. Un système de chromatographie liquide native-spectrométrie de masse peut comprendre un système de chromatographie liquide permettant de séparer un échantillon ; et un système de spectrométrie de masse à ionisation par électronébulisation (ESI-MS) en communication fluidique avec le système de chromatographie liquide, le système d'ESI-MS comprenant un émetteur d'ionisation par électronébulisation à buses multiples et un système pour modifier un gaz de désolvatation et un spectromètre de masse, le spectromètre de masse étant conçu pour recevoir des ions et caractériser le rapport masse/charge des ions.
Patent CA-3170121-A1 (CA)
Title: Pyrrolo[2,3-b]pyridine-3-carboxamide compositions and methods for ameliorating hearing loss
Inventor: GNEDEVA KSENIA
IPC: C07D471/04
Filed: 2021-02-05
Abstract: N-(3-Substituted thiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamides and N-(3-substituted oxazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamides (I) and (II) are disclosed. The compounds activate Yap and inhibit Lats kinases. They are therefore useful for treating hearing loss.
Patent CA-3172047-A1 (CA)
Inventor: CHOI CHUL-HONG
IPC: C30B15/04
Filed: 2019-09-16
Abstract: Provided is a method for manufacturing a synthetic gemstone, which manufactures a synthetic gemstone from at least one of a hair, a fingernail, and a toenail separated from a person or an animal, the method including: extracting a biological material from at least one of the hair, the fingernail, and the toenail; preparing a mixed material by mixing the biological material with a gemstone material; and growing a synthetic gemstone on a crystal seed as a single crystal by melting the mixed material.
Patent CA-3172449-A1 (CA)
Title: Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
Inventor: MANTING ERIK HANS
IPC: C12N5/0783
Filed: 2021-03-26
Abstract: The present disclosure provides ex vivo methods which employ modified cells of leukemic origin to enhance the efficacy of adoptive cell therapy.