baber/WOPTO huggingface dataset:
Patent CA-1273934-A (CA)
Inventor: BROWN FREDERICK J
IPC: C07D209/08
Filed: 1985-10-18
Granted: 1990-09-11
Abstract: A B S T R A C T        HETEROCYCLIC AMIDE LEUKOTRIENE ANTAGONISTS     The invention provides a series of novel heterocyclic amides of the formula I in which the group A.CRa can be -CRb=CRa-, -CHRb-CHRa- or -N=CRa-, the amidic group Re.L can be Re.X.CO.NH, Re.X.CS.NH or Re.NH.CO attached at position 4, 5 or 6 of the benzenoid moiety, Z is an acid group selected from the group consisting of carboxy, an acylsulphonamide residue of the formula CO.NH.SOnRa and a tetrazolyl residue of the formula II, and the radicals Ra, Rb, Rc, Rd, Re, Rf, Rg, Rh, n, X, G1, Q and G2 have the meanings defined in the following specification.         The compounds of formula I are leukotriene antagonists.  The invention also provides pharmaceutically acceptable salts of the formula I compounds; pharmaceutical compositions containing the formula I compounds, or their salts, for use in the treatment of, for example, allergic or inflammatory diseases, or endotoxic or traumatic shock conditions; and processes for the manufacture of the formula I compounds, as well as intermediates for use in such manufacture.
Patent CA-1260944-A (CA)
Inventor: GUNTHER WOLFGANG H H
IPC: C09B23/02
Filed: 1985-10-23
Granted: 1989-09-26
Abstract: NOVEL OXACHALCOGENAZOLE DYES, PROCESSES FOR THEIR PREPARATION, AND    ARTICLES CONTAINING THESE DYES   Abstract of the Disclosure Methine dyes are disclosed which in alternate resonance forms can be represented by the formulae:                    wherein E represents an auxochrome; L represents a methine linkage; M represents a charge balancing counterion; m is zero or 1; X represents halogen or a pseudohalogen; and Z represents the atoms completing an aromatic nucleus.  The dyes can be formed by condensing a compound satisfying the formula:          wherein H* is an activated hydrogen and q is zero or 1, with a chromophore completing compound.  The dyes are useful in optical recording elements and in photo-graphic elements.
Patent CA-1250122-A (CA)
Inventor: SMITS PHILIPPUS R J
IPC: E04D5/12
Filed: 1985-10-25
Granted: 1989-02-21
Abstract: ABSTRACT           The invention relates to a roofing-material provi-ded with perforations and comprising a bituminized carrier with a non-sticking lower surface and destined for being applied on a substratum and for being covered by an upper layer,which may contain a carrier which is bituminized with modified bitumen, and which may be applied by means of a torch.   According to the invention the carrier of the roofing-material is bituminized with modified bitumen, and the perforations are so large that the upper layer can be directly applied on the roofing-material by means of a torch and can be adhered to the substratum via the perforations.
Patent CA-1263415-A (CA)
Title: Apparatus for aligning a wicketer stacking station with an edge of a web
Inventor: EBMEYER WILFRIED
IPC: B31B50/98
Filed: 1985-11-06
Granted: 1989-11-28
Abstract: ABSTRACT     Apparatus is provided for aligning with an edge of a tubular or semitubular plastic web a wicketer stacking station comprising transfer arms, which are mounted for rotation about an axis and serve to take over bags, which have been severed from a tubular or semitubular plastic web and closed by a seam weld.  Said arms are adapted to thread the bags formed with punched locating holes onto respective pairs of stacking pins provided on intermittently driven tensile means of an endless conveyor which constitutes a stacking line, whereby stacks are formed.  Said apparatus comprising means for sensing the position of said edge of the web and an actuator for transversely displacing the wicketer stacking station in dependence on the measured deviation of said edge.  In order to permit a simple and sensitive adjustment of the wicketer stacking station in response to a deviation of the web, the wicketer frame, in which the transfer arms are rotatably mounted, is provided with at least one transverse rail, which is supported on rollers or sliding surfaces of a carrying frame.  The wicketer frame is connected by a beam to an end frame, which receives the receiving end of the stacking line and is supported on a base frame and is longitudinally displace-able and rotatable through a small angle relative to said base frame.  The actuator is mechanically connected only to the wicketer frame adjacent to said transverse rail.
Patent CA-1263367-A (CA)
Inventor: BEST STEVEN A
IPC: C08F4/639
Filed: 1985-11-21
Granted: 1989-11-28
Abstract: ABSTRACT OF THE DISCLOSURE          A  vanadium-containing  catalyst  component  useful  for  the polymerization  of  olefins  to  polyolefins  having  a  high  molecular weight  and  a   broad  molecular  weight   distribution   comprising polymerizing the polyolefins in the presence of a catalyst comprising (A) a vanadium-containing catalyst component obtained by contacting an inert  support  material  with  a  dihydrocarbyl  magnesium  compound, optionally an oxygen-containing compound, a vanadium compound, a Group III metal halide, and (B) an aluminum alkyl cocatalyst.
Patent CA-1255306-A (CA)
Inventor: CARMOSIN RICHARD J
IPC: C07D211/22
Filed: 1986-01-07
Granted: 1989-06-06
Abstract: OCTAHYDROINDOLIZINE COMPOUNDS USEFUL AS ANALGESICS            ABSTRACT            Octahydroindolizidines of the formula (1):                            (I) where A is a 3-7 carbon or hetero-containing ring, R1 is a substituent and x is 0-3.  Also, pharmaceutical composition for treating pain and methods for synthesis and use as well as novel intermediates in the synthesis.
Patent CA-1270275-A (CA)
Inventor: KUGLER UWE H
IPC: F16L37/28
Filed: 1986-01-14
Granted: 1990-06-12
Abstract: IMPROVED FEMALE COUPLER FOR A FLUID CIRCUIT         Abstract of the Disclosure A female coupler for engagement with a male coupler which has a spring loaded check valve, the female coupler includes a main poppet valve biased to a normally closed position and movable by the check valve in the male coupler to a fully opened position, a piston responsive to fluid pressure in the female coupler to force the main poppet valve to an intermediate position and open the male coupler check valve, a flow check prevention valve for normally maintaining a predetermined pressure of the fluid acting on the piston, and a second poppet valve to relieve the fluid acting on the piston.
Patent CA-1254775-A (CA)
Inventor: CARTWRIGHT KENNETH L
IPC: B25B13/00
Filed: 1986-03-07
Granted: 1989-05-30
Abstract: REVERSIBLE WRENCH HAVING INSTANTANEOUSLY          GRIPPING FRICTION DRIVE            Abstract of the Disclosure The present invention is comprised of a handle having an enlarged head at one end with a cylindrical bore passing through it.  A drive element rotatably located in the bore has three equally spaced planar cam faces which are separated by circular segments having a radius approximately equal to the radius of the bore.          Elongate rollers which fit in the three semi-cylindrical portions of the bore remaining between the drive element and the periphery of the bore, have diameters which are approximately 0.002 less than the maximum distance bet-ween the cam faces and the periphery of the bore.  A selector rotatably attached to the drive element has three pairs of prongs with one of the prongs in each pair being located on each side of a roller.  A detent which is operative between the drive element and the selector causes the rollers to be completely wedged bet-ween the cam faces and the periphery of the bore when the selector head is rotated to either side of center and locks them in this wedged position during use.  This is accomplished by providing balls on one of the ele-ments and cavities on the other element which receives the balls a minimal amount intermediate their ends and more fully at their extremities with the balls being positioned at the extremities of the cavities when the rollers are in their fully wedged positions.
Patent CA-1259230-A (CA)
Inventor: BOLLE ROBERT
IPC: B63H21/32
Filed: 1986-03-24
Granted: 1989-09-12
Abstract: ABSTRACT OF THE DISCLOSURE             A marine propulsion device including a propeller shaft, a lower unit rotatably supporting the propeller shaft and including a lower unit exhaust passageway, a propeller adapted to be submerged in water and including an inner hub connected to the propeller shaft.  The propeller also includes an outer hub connected to and spaced from the inner hub and defining a propeller exhaust passageway having an inlet in communication with the lower unit exhaust passageway, and a plurality of blades extending from the outer hub rearwardly of the inlet, an opening for communicating the lower unit exhaust passageway with water outside of the outer hub, and a member located adjacent and rearward of the opening, and extending forwardly and radially outwardly with respect to the propeller shaft.
Patent CA-1249954-A (CA)
Inventor: VRIJSSEN GERARDUS A H M
IPC: H01J29/62
Filed: 1986-03-27
Granted: 1989-02-14
Abstract: PHN 11.330                12 ABSTRACT:     The invention relates to a method of manu-facturing a device in which a homogeneous electrical resistance layer of a resistive material having a resistivity of at least 10 ohm.cm is formed on an insulating substrate.  According to the invention a stable binder-free suspension containing ruthenium hydroxide and glass particles is provided on the insulating substrate from which a ruthenium oxide-containing electrical resistance layer is formed by heating.  The method according to the invention may be used successfully, for example, in the manufacture of cathode ray tubes.
Patent CA-1247113-A (CA)
Inventor: BLAISDELL CHARLES T
IPC: C07D307/84
Filed: 1986-04-22
Granted: 1988-12-20
Abstract: TITLE PROCESS FOR THE PREPARATION OF METHYL CARBAMATES         Abstract of the Disclosure A continuous, close-coupled method for making N-methyl carbamate pesticides which comprises con-tacting the methyl isocyanate in a vapor phase mix-ture containing methyl isocyanate and water with a selected oxime or phenol, said mixture being the reaction product formed by oxidizing monomethylform-amide.  An optional intermediate step for preparing the methyl isocyanate/water vapor phase reaction mix-ture for contact with the oxime or phenol is to remove therefrom a portion of the water without liquefying the methyl isocyanate by cooling the mixture to a temperature below the dew point of water but above the dew point of the methyl isocyanate.
Patent CA-1250570-A (CA)
Inventor: HOFMEISTER HELMUT
IPC: C07J1/00
Filed: 1986-05-09
Granted: 1989-02-28
Abstract: ABSTRACT OF THE DISCLOSURE        A process and novel starting materials for the production of 17.alpha. -ethynyl-17.beta. -hydroxy-18-methyl-4,15-estradien-3-one of Formula I                  ( I ) are disclosed.  Novel 17-ketone starting materials  have the Formula II                        (II), wherein R  is an alkyl residue of 1-3 carbon atoms and B    is the grouping      or         A    wherein R' is an acyl group of up to 10 carbon atoms.
Patent CA-1273259-A (CA)
Inventor: STODDART BARRY
IPC: C11D3/395
Filed: 1986-05-27
Granted: 1990-08-28
Abstract: ABSTRACT            Aqueous cleaning compositions displaying shear thinning behaviour are provided, comprising from 0.1% to 5% by weight C12-C15 alkyl amine oxides, together with from 0.05 to 0.5% by weight of an alkylated benzene or naphthalene sulphonate, at a weight ratio of amine oxide to alkylated benzene sulphonate of from 2.5:1 to 10:1. Compositions containing alkali metal hypochlorite bleach are disclosed in which the preferred alkylated benzene sulphonate is sodium cumene sulphonate.
Patent CA-1263128-A (CA)
Inventor: COLIMITRA THOMAS A
IPC: F16H1/00
Filed: 1986-07-10
Granted: 1989-11-21
Abstract: - 15 -                52,274 ABSTRACT OF THE DISCLOSURE     A remotely operated hand gear train for the orientation of an end effector has an external housing mounted onto a robot arm and defines a first axis A1.  A first housing is rotatably mounted within the external housing for movement about the first axis A1 and defines therein a second axis A2 which is substantially perpendicular to the first axis A1.  A second housing is rotatably mounted in the first housing for rotation about the second axis A2 and defines therein an axis A3 which is normal to axis A2 and radially spaced from axis A1.  A third housing is rotatably mounted in the second housing for rotation about axis A3 and has a gear rack circumferentially disposed about the end thereof.
Patent CA-1257514-A (CA)
Inventor: NEARY JOHN F
IPC: A01K1/01
Filed: 1986-08-29
Granted: 1989-07-18
Abstract: ABSTRACT     A self-drying pet litter box includes a box-like container having upwardly extending sides, a foraminous panel within the container and a structure for supporting the panel horizontally above the bottom of the container so that the upper surface of the panel will support particulate litter.  Means for heating the panel in order to destroy bacteria may also be provided.
Patent CA-1259585-A (CA)
Inventor: GILLISPIE JOHN G
IPC: B65D47/24
Filed: 1986-10-15
Granted: 1989-09-19
Abstract: Abstract A safety container having two openings, one having a pouring spout attached thereto, the second having a filler tube attached  thereto with  a  spring-biased  safety cap thereon,  a rigid carrying handle mounted between the pouring spout and the filler tube, and means extending below the carrying handle for opening  the  pouring  spout  and  simultaneously  lifting  the spring-biased safety cap.
Patent CA-1272363-A (CA)
Inventor: STEINMETZ HANS-WERNER
IPC: B29C65/00
Filed: 1987-05-29
Granted: 1990-08-07
Abstract: ABSTRACT OF THE DISCLOSURE      An adapting piece of thermoplastic material includes at least one welding sleeve portion with an electrical heating device formed by two heating mats arranged next to each other in circumferential direction.  The welding sleeve portion has at least one radial incision extending in axial direction.  By means of a clamping nut, the welding sleeve portion can be braced together with the heating elements against a tubular piece inserted in the welding sleeve portion.  As a result, the pieces are fixed and supported before and during welding.
Patent CA-1250435-A (CA)
IPC: B24B13/00
Filed: 1987-08-20
Granted: 1989-02-28
Abstract: ABSTRACT OF THE DISCLOSURE           A method and article of manufacture allows great accuracy in machining the edge of a face on a prism to a predetermined position respect-ive a feature carried on the face and formed by deposition of insulating material.  The preferred application for this invention is in accurately machining the transducing surface of a disk memory transducer assembly so that the throat height of the thin film head carried on an end face of the assembly has a precise value.
Patent CA-1245362-A (CA)
Inventor: SZETO LAI-WAN M AXSMITH CRES W
IPC: G01R23/16
Filed: 1987-10-26
Granted: 1988-11-22
Abstract: INVENTOR: LAI-WAN M. SZETO                   TITLE: APPARATUS FOR, AND METHOD       OF, MEASURING TIME DELAY                     ABSTRACT OF THE DISCLOSURE           An apparatus for, and method of, analysing a signal takes the Fourier Transform of both a first signal and a shifted signal, which has previously been subjected to a shift, for example a time-shift, relative to the first signal.  This gives sets of first and second frequency components corresponding respectively to the first signal and the shifted signal.  The arguments of at least one pair of corresponding first and second frequency components are calculated, and subtracted to give a phase difference.  From this phase difference, the time-shift or time delay of the corresponding constituent of the first signal can be determined.
Patent CH-550003-A (CH)
Title: N-hydroxyalkyl-iodomethanesulphonamides - which are non-ionogenic water-soluble radiopaque substances
IPC: A61K49/04
Filed: 1971-03-23
Abstract: Title cpds. of formula I-CH2-SO2-NR-R1 (I) (where R is CH3 or H and R1 is 2-hydroxyethyl, 2-(2-hydroxethoxy)-ethyl, 2,3-dihydroxypropyl or alpha, gamma-dihydroxyisopropyl) are radiopaque substances particularly of use in X-ray contrast agents for visualising fluid cavities (esp. in radiculography, myelography, myeloencephalography and ventriculography) which have the advantages of being non-ionogenic and very readily water-soluble and of having low osmotic pressure. (I) are prepd. by reacting a cpd. I-CH2SO2X with a cpd. Y-R11 and removing any possible OH-protecting gps. from the product (where one of X and Y is Cl, Br, I, alkylsulphonyloxy or arylsulphonyloxy and the other is -NH-R, and R11 is a gp. corresponding to R1 in which OH gps. are opt. masked by protecting gps. readily removable by careful hydrolysis or hydrogenolysis).
Patent CH-525237-A (CH)
Title: Penicillin derivs antibacterial
Inventor: KENNETH DAVID HARDY
IPC: C07D499/00
Filed: 1968-04-18
Abstract: (A) Penicillin derivs. (I) R = phenyl, substd. phenyl, furyl or thienyl. Preferred compounds have R = phenyl or 3-thienyl. (B) Non-toxic salts of A such as metal salts, ammonium- and substd. ammonium salts e.g. trialkylamines, procaine, dibenzylamine, N-benzyl-beta-phenethylamine, 1-ephenamine, N,N'-dibenzylethylenediamine, dehydroabietylamine, N,N'-bisdehydroabietylethylenediamine and other amines used for the forming of salts with benzylpenicillin. Anti-bacterial activity; where R = phenyl or 3-thienyl (I) are very active in the treatment of infections caused by Pseudomonas bacteria such as Ps.pyocyanea.
Patent CH-535767-A (CH)
Title: 1-phenethyl-4-arylamino-piperidines - with analgesic activity
Inventor: ERHARD SCHENKER
IPC: C07D211/58
Filed: 1970-04-25
Abstract: Title cpds. of formula (I) (where R1 is H, halogen, lower alkyl, alkylthio or alkoxy, CF3, NO2, NH2, CN or acetamido; R2 is 1-naphthyl, 1,2,3,4-tetrahydro-5-naphthyl or 5-indanyl opt. subst. in the aromatic ring by halogen, lower alkyl, alkylthio or alkoxy, CF3, NO2, NH2, CN or acetamido; and R3 is H or lower acyl; with the proviso that R2 is not subst. by NH2 when R3 is lower acyl) and their salts with acids are prepared by condensing a compound of formula (II) with a compound of formula (III) (where X is a residue which is split off under the reaction conditions to form XH, e.g. Cl, Br, I or the acid residue of an organic sulphonic acid) in an inert solvent in the presence of an acid binding agent and opt. converting the product into an acid addn. salt. Products in which R3 is H, R1 is other than NH2, and R2 is not substd. by NH2 may be reacted with cpds. furnishing a lower acyl residue so as to yield corresponding cpds. in which R3 is acyl.
Patent CH-512436-A (CH)
Title: Analgesic basic anthranilamide derivs
Inventor: BORGE ALHEDE
IPC: C07D265/26
Filed: 1968-07-02
Abstract: Cpds. of general formula (I) and their salts. R1 = H, 1-5 C alkyl (pref. Me) R2 = 2-5 C alkylene (pref. C2H4, C3H6) R3R4 = Me2, Et2 or MeEt R5,6 = H, 1-5 C alkyl, halogen, CF3; both is not = H and not para to NH As analgesics of low toxicity. No antipyretic or Straub effect in mice. As active as codeine, but not narcotic.
Patent DK-196282-A (DK)
Inventor: AALBERSE R C
IPC: G01N33/537
Filed: 1982-04-30
Abstract: The invention relates to a method for the assay of antibodies to soluble antigens in an aqueous sample, in particular in body fluids, such as blood serum or blood plasma, by contacting said sample with an antigen in vitro, wherein antibodies, if present, are bound by said antigens. The invention furthermore relates to a kit for the assay and detection of antigen-specific antibodies. According to the invention an antigen is used that is modified with a recognizable group, and said modified antigen is soluble in the test sample. The interaction between antigen and antibody takes place in homogeneous solution.
Patent DK-265990-A (DK)
Inventor: CHIEN YIE W
IPC: A61K31/565
Filed: 1990-11-06
Abstract: Transdermal absorption dose units for treating post- menopausal syndrome have been developed, which dose units comprise a supporting layer and an adjacent adhesive polymer layer in which at least a minimum effective daily dose of an oestrogen is microdispersed. At the present moment, preference is given to using the naturally occurring oestrogen 17-β-oestradiol or ethynyloestradiol, or combinations thereof together with a quantity of naturally occurring progestogen or a progestin in order to minimize any possible side-effects. The units employ bioacceptable adhesives and polymers. An additional polymer layer which is in close contact with the oestrogen-containing layer can also be used. Where appropriate, it is also possible to use a separating layer for producing the dose units, with this layer separating the two adhesive polymer layers and allowing the transfer of oestrogen from the first adhesive polymer layer during the treatment. This results in dose units which transdermally release at least minimum daily doses of the oestrogen for at least one day or for a number of days, such as a week. This results, finally, in a process for treating post menopausal syndrome using the novel dose units.
Patent DK-348987-A (DK)
Inventor: STEENHUISEN JOHANNES E
IPC: A61M5/00
Filed: 1987-07-07
Abstract: The invention relates to a holder for a plurality of disposable syringes, the syringes comprising a barrel (11), a needle connection means (19) on the front end of the barrel, in which or to which an injection needle (13) is or can be sealingly connected, and a finger grip (16), provided with an outwardly projecting flange (31) and optionally with a clamping sleeve (18) for a clamping connection around the rear open end of the barrel. The holder comprises comprises a strip (24) of flexible material one side of which comprises a number of resilient projections (23), distributed over the surface, for a detachable connection of the syringes in such a way that the rear end of the barrel or the rear face of the finger grip (16) adjoins the surface of the strip in a non-sealing manner.
Patent DK-355486-A (DK)
Inventor: HABERMANN PAUL
IPC: C12P21/02
Filed: 1986-07-25
Abstract: 1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A fusion protein of the general formula Met - Xn - D' - Y - Z in which n is zero or 1, X is a sequence of 1 to 12 genetically codable amino acids, D' is a sequence of about 70 amino acids in the region of the sequence of amino acids 23 - 93 of the D-peptide in the trp operon of E. coli, Y denotes a sequence of one or more genetically codable amino acids which permits the following amino acid sequence Z to be cleaved off, and Z is a sequence of genetically codable amino acids. 1. Claims for the Contracting State : AT A process for the preparation of a fusion protein of the general formula (1) Met - Xn - D' - Y - Z in which n is zero or 1, X is a sequence of 1 to 12 genetically codable amino acids, D' is a sequence of about 70 amino acids in the region of the sequence of amino acids 23 - 93 of the D-peptide in the trp operon of E. coli, Y denotes a sequence of one or more genetically codable amino acids which permits the following amino acid sequence Z to be cleaved off, and Z is a sequence of genetically codable amino acids, characterized by expressing a gene structure which codes for these fusion proteins in a host cell, and separating the fusion protein.