baber/WOPTO huggingface dataset:
Patent CA-3057899-A1 (CA)
Inventor: CHUAH LAY KHIM
IPC: C12N15/861
Filed: 2018-03-27
Abstract: La présente invention concerne des éléments régulateurs d'acides nucléiques qui sont capables de renforcer l'expression de gènes spécifiques au diaphragme, en particulier l'expression dans le diaphragme en tant que tel, ou en association avec l'expression dans le muscle cardiaque et/ou les muscles squelettiques. L'invention concerne également des méthodes utilisant ces éléments régulateurs et leurs utilisations. L'invention concerne également des cassettes et des vecteurs d'expression contenant ces éléments régulateurs d'acides nucléiques. L'invention est particulièrement utile dans des applications utilisant la thérapie génique, plus particulièrement la thérapie génique orientée sur le diaphragme, et à des fins de vaccination.
Patent CA-3067405-A1 (CA)
Inventor: BENDJAMA KAIDRE
IPC: C12N7/00
Filed: 2018-06-21
Abstract: The present invention generally relates to a personalized cancer vaccine comprising a recombinant poxvirus encoding one or more neopeptide(s) or a composition comprising such a recombinant poxvirus and a pharmaceutically acceptable vehicle as well as the use of said personalized cancer vaccine for treating a cancerous subject in need thereof. A specific embodiment is directed to a method of providing such a vaccine or composition comprising an identification step comprising a) extracting the DNA from a tumor sample and a non-tumor sample, b) selecting target regions, preferably the entire coding regions of the genome (exome), c) sequencing said target regions (e.g. the exome) from said extracted DNAs and d) identifying one or more tumor-specific mutation(s) by comparing the DNA sequences obtained from said tumor and non-tumor samples. Embodiments also include a method of treating cancer or preventing its relapse comprising administration of such a personalized cancer vaccine. The invention is of very special interest in the field of personalized immunotherapy, specifically for stimulating T cell immune response.
Patent CA-3069757-A1 (CA)
Inventor: MANOLAKOS ALEXANDROS
IPC: H04L5/14
Filed: 2018-07-25
Abstract: Selon un aspect, l'invention concerne un procédé, un support lisible par ordinateur et un appareil. L'appareil peut être une station de base ou un UE. Selon un aspect, l'appareil peut déterminer des emplacements pour un certain nombre de symboles DM-RS à transmettre dans une unité de planification d'un canal configuré dans un intervalle/mini-intervalle, un dernier symbole DM-RS pouvant être positionné un symbole avant un dernier symbole portant des données planifiées. Selon un autre aspect, l'appareil peut déterminer les emplacements pour les symboles DM-RS sur la base d'une sélection entre un premier ensemble de positions DM-RS prédéfinies et un second ensemble de positions DM-RS prédéfinies. Selon un autre aspect, l'appareil peut déterminer les emplacements pour les symboles DM-RS sur la base d'un nombre défini de symboles, les emplacements déterminés étant espacés selon le nombre défini de symboles. L'appareil peut transmettre les symboles DM-RS sur la base des emplacements déterminés.
Patent CA-3070245-A1 (CA)
Title: Bus steering system
Inventor: HALLUNDBAEK JORGEN
IPC: B62D7/18
Filed: 2020-01-29
Abstract: A steering unit (32) for a vehicle, notably a bus. The steering unit (32) is coupled with a suspension system and comprises: a support formed by a passenger platform and a wheel housing, a longitudinal axis, a steering knuckle (76) with an in-wheel engine (60) exhibiting a transversal rotation axis which is arranged transversally with respect to the longitudinal axis, an actuator mechanism (48) adapted for pivoting the steering knuckle. The steering knuckle (76) further comprises a lever (82) which is linked to the actuator mechanism (48) and which includes a transversal portion (94) extending transversally along the in-wheel engine (60). The invention is adapted for an articulated bus with at least two bodies, said bodies each exhibits four or eight identical and independent steering units (32).
Patent CA-3070788-A1 (CA)
Inventor: JEROMSON PETER JAMES
IPC: F16K11/22
Filed: 2018-08-08
Abstract: Deux problèmes rencontrés avec des vannes de mélange à commande électronique existantes à usage domestique sont leur taille et leur difficulté d'accès et de réparation de celles-ci. Leur taille implique qu'elles sont souvent cachées derrière les revêtements muraux, et en raison de la façon dont elles sont branchées dans la tuyauterie d'une maison, elles sont difficiles d'accès et à retirer pour la réparation ou le remplacement. La solution proposée dans la présente invention est une cartouche de vanne de mélange compacte et remplaçable qui peut être accouplée à un raccord fixe qui est branchée de façon permanente dans la tuyauterie d'une maison. La taille compacte permet à la cartouche d'être positionnée derrière le type de plaques de face amovibles qui sont souvent installées sur des vannes de mélange actionnées manuellement existantes. Des actionneurs de soupape simplifiés et une configuration compacte de mélange et de détection de température ont facilité l'obtention d'une taille compacte. L'accès à la cartouche de valve est d'accès facile, et elle peut être déboulonnée et retirée, sans avoir besoin d'une refonte complète de plomberie.
Patent CA-3072379-A1 (CA)
Inventor: THOMAS KURT J
IPC: C04B35/185
Filed: 2018-09-25
Abstract: La présente invention concerne la fabrication de produits céramiques par coulage de gel aqueux. Des exemples de produits céramiques comprennent des articles sanitaires, tels que des toilettes et des éviers. Le procédé comprend une étape de mise en suspension, une étape de mélange, une étape de moulage impliquant un coulage de gel aqueux, une étape de séchage, une étape d'émaillage et une étape de cuisson.
Patent CA-3073221-A1 (CA)
Inventor: KENDALL William Garnet
IPC: E21D20/00
Filed: 2018-08-28
Abstract: Disclosed herein are material handling systems for a roof bolter that provide the ability to store and manipulate a large number of roof bolts as well as reduce operator effort and provide improvements in safety, efficiency and accuracy of bolt installation. Examples of material handling systems for a roof bolter include a plurality of roof bolts and a storage pod including a plurality of spaced, fixed holders, each fixed holder receiving at least one of the plurality of roof bolts. The plurality of spaced, fixed holders include a first plurality of openings in a first aligned row extending in a first direction, and a second plurality of openings in a second aligned row extending in a second direction generally perpendicular to the first direction.
Patent CA-3080156-A1 (CA)
Inventor: IVESTER ALLEN
IPC: H04L51/10
Filed: 2018-10-23
Abstract: L'invention concerne une plateforme de messages configurée pour recevoir des données de message vidéo et corréler les données de message vidéo avec des données de livraison associées à un ou plusieurs articles, générer un bordereau de colisage ayant un identifiant unique, recevoir une demande de récupération de message basée sur l'identifiant unique et amener les données de message vidéo à être transmises à un dispositif d'utilisateur destinataire.
Patent CA-3080500-A1 (CA)
Inventor: SANBORN ALEXANDRA
IPC: C09K15/08
Filed: 2014-02-25
Abstract: Disclosed is a process for making HMF' or a derivative of HMF by dehydrating one or more hexose sugars in a reduced oxygen environment, in another, related aspect, a method for improving the stability and resistance to degradation of an HMF  product Involves adding one or more antioxidants to the HMF product.
Patent CA-3085208-A1 (CA)
Inventor: WEBER BEAT
IPC: A61K31/465
Filed: 2018-12-18
Abstract: The present invention relates to a method of separating racemic nicotine of Formula (l-a) as a mixture of the (R)- and (S)-enantiomers into the enantiomerically pure (S)- and (R)-nicotine represented by Formula (l-b) and (l-c), by adding a mixture of the L- and the D-enantiomer of a O,O'-disubstituted tartaric acid, wherein the molar ratio of the L- to the D-enantiomer is from 80:20 to 95:5, and obtaining the (S)-nicotine of formula (l-b), or by adding O,O'-dibenzoyl-D-tartaric acid and obtaining the (R)-nicotine of formula (l-c).
Patent CA-3091714-A1 (CA)
Inventor: BARRETT STEPHEN JOHN
IPC: H04L12/58
Filed: 2019-04-05
Abstract: Abstract A method at a network element for processing a first message destined for an intelligent transportation system station, the method including receiving from a sending entity, or generating, the first message at the network element; based on a source or contents of the first message, performing one of: discarding the first message; or modifying the first message to provide an indication to the intelligent transportation system station of checks the intelligent transportation system does not need to perform, thereby creating a second message; and forwarding the second message to the intelligent transportation system station.
Patent CA-3092320-A1 (CA)
Inventor: JIANG JING
IPC: A61K38/18
Filed: 2019-12-04
Abstract: The present invention relates to a bifunctional angiogenesis inhibitor having VEGF inhibitory activities and FGF inhibitory activities and capable of inhibiting VEGF and FGF dual factors or high sugar-induced cell proliferation, cell migration and/or lumen formation. The present invention also relates to use of the bifunctional vascular inhibitor for inhibiting retinal angiogenesis, such as diabetic retinopathy, age-related macular degeneration.
Patent CA-3094239-A1 (CA)
Title: Measuring a posterior corneal surface of an eye
Inventor: NEKRASSOV DANIIL
IPC: A61B3/107
Filed: 2019-05-08
Abstract: In certain embodiments, a system for measuring the posterior corneal surface of the cornea comprises cameras and a computer. Each camera generates image data representing a part of the eye posterior to the cornea. The image data describes locations of features of the part. The computer stores a description of the shape of an anterior corneal surface of the cornea, and applies a ray-tracing process to determine the shape of the posterior corneal surface. The ray-tracing process comprises defining rays, where each ray is traced from a camera, through the anterior and posterior corneal surfaces, and to the part of the eye. Constraints for the rays are determined, where the constraints are calculated using the description of the shape of the anterior corneal surface and locations of the features in the image data. Parameters are optimized, and the optimized parameters describe the shape of the posterior corneal surface.
Patent CA-3096175-A1 (CA)
Title: Raised planter
Inventor: ROY YVON
IPC: A01G9/02
Filed: 2020-10-15
Abstract: A raised planter is provided. The raised planter comprises a tray adapted for containing soil and a plurality of support posts mounted to the tray, the support posts being adapted for supporting the tray at a predetermined height above ground.
Patent CA-3097378-A1 (CA)
Title: Compositions et procedes pour la liberation prolongee de flecainide
Inventor: FISHEL ROBERT
IPC: A61K31/4458
Filed: 2019-04-16
Abstract: L'invention concerne de manière générale des compositions à libération prolongée. Spécifiquement, l'invention concerne des compositions biphasiques et triphasiques et des procédés pour contrôler la libération d'un médicament destiné à traiter une maladie cardiaque.
Patent CA-3098905-A1 (CA)
Title: Valveless fluidic switching flowchip and uses thereof
Inventor: CROMWELL EVAN FRANCIS
IPC: B01L3/00
Filed: 2019-04-30
Abstract: Provided are valveless microfluidic flowchips comprising fluid flow barrier structures or configurations. Further provided are systems and methods having increased fluid transfer control in a valveless microfluidic flowchip. The systems and methods can be used in the present valveless microfluidic flowchips as well as in currently available valveless microfluidic flowchips.
Patent CA-3099791-A1 (CA)
Inventor: GINTY DAVID D
IPC: C07D471/04
Filed: 2019-05-29
Abstract: La présente invention concerne de nouveaux analogues non benzodiazipèniques à restriction périphérique présentant une perméabilité de barrière hématoencéphalique réduite et des méthodes d'utilisation de ceux-ci pour réduire un dysfonctionnement tactile, une déficience sociale, et l'anxiété chez un sujet chez qui a été diagnostiqué un trouble du spectre autistique, un syndrome de Rett, un syndrome de Phelan-McDermid, ou un syndrome de l'X fragile, ou de traitement de la surréactivité tactile, de la douleur ou de l'allodynie mécanique.
Patent CA-3100478-A1 (CA)
Title: Ophthalmic laser surgical system and method implementing simultaneous laser treatment and oct measurement
Inventor: SIMONEAU MICHAEL J
IPC: A61B18/20
Filed: 2020-02-04
Abstract: In an ophthalmic laser surgical system, a real-time optical coherence tomography (OCT) measurement method acquires OCT data during laser treatment. The treatment laser beam and OCT sample beam are generated simultaneously, and the optical delivery system scans them simultaneously in the eye tissue, where the focus of the treatment laser beam and the focus of the OCT beam coincide with each other in space. While both beams simultaneously scanned in the eye tissue, the OCT device detects returned OCT light from the sample during a data acquisition period, and generates an OCT A-scan based on the detected OCT light. Based on the A-scan, a controller determines a structure of the eye in a depth direction relative to the focus of the OCT beam, and controls the operations ophthalmic laser surgical system accordingly. One exemplary application is the formation of an arcuate corneal incision in cataract surgery.
Patent CA-3101025-A1 (CA)
Title: Method for preparing an aqueous dispersion of metal oxide particles
Inventor: BANSAL VIPUL
IPC: C01G49/06
Filed: 2019-05-22
Abstract: A method for preparing an aqueous dispersion of metal oxide particles is disclosed. The method comprises the step of performing phase transfer of a plurality of metal oxide particles capped with hydrophobic ligands on a surface there of by contacting the metal oxide particles with a combination of tertiary amine and water to form a biphasic mixture, and agitating said biphasic mixture to produce an aqueous dispersion of metal oxide particles capped with hydrophobic ligands and tertiary amine ligands on the surface thereof.
Patent CA-3101158-A1 (CA)
Title: Splicable environmentally-friendly non-pvc advertising cloth made of a woven structure
Inventor: LIN I-CHIEN
IPC: G09F23/00
Filed: 2020-11-30
Abstract: ABSTRACT A splicable environmentally-friendly non-PVC advertising cloth made of a woven structure, wherein the advertising cloth comprising a mesh base layer (40); a first adhesion-promoting structural layer (10), which is a refractory and waterproof layer covering the front surface (43) and the rear surface (44) of the mesh base layer (40); a second adhesion-promoting structural layer (20) coated on the first surface (13) of the first adhesion-promoting structure layer (10); and a third adhesion-promoting structural layer (30) coated on the upper surface (24) of the second adhesion-promoting structure layer (20), therefore, waterproof and ink-absorbing structure arranged on a mesh base (40) layer, and the width of the advertising cloth (50) can be spliced unlimitedly as required by using high frequency splicing, making the environmentally friendly advertising cloth more applicable also improving the overall advertising effect and quality. Date Recue/Date Received 2020-11-30
Patent CA-3101591-A1 (CA)
Title: Implant corneen
Inventor: GROSSO EDOARDO
IPC: A61F2/14
Filed: 2019-05-31
Abstract: La présente invention concerne un implant cornéen (1) conçu pour corriger les irrégularités de la courbure cornéenne d'un sujet, l'implant (1) ayant un corps structurel (2) généralement en forme de dôme configuré pour imposer une courbure régulière aux portions cornéennes conçu pour être en contact avec l'implant, où le corps structurel comprend un anneau périphérique externe (10) et une structure réticulaire interne (20), la structure réticulaire interne (20) comprenant au moins une première et une seconde série de faisceaux (21, 22) en intersection l'une avec l'autre, les faisceaux (21) de la première série ayant une première extrémité respective (31) reliée à l'anneau périphérique externe (10), où la surface totale des parties de vide (24) à l'intérieur des mailles de la structure réticulaire (20) est comprise entre 50 et 99,9 % de la surface de la structure réticulaire (20).
Patent CA-3101616-A1 (CA)
Title: Apparatus and method for heat treating wood
Inventor: BLOYE DWIGHT FREDERICK
IPC: B27K5/00
Filed: 2020-12-03
Abstract: ABSTRACT  A method of heat treating a wood board comprises: passing a wood board from an input end to a discharge end of a conveyor; and heating the board with radiant heat as it is passes along the conveyor, the heating can be such as to provide significant charring of the wood. The wood board is then brushed with at least one rotating brush. An apparatus, for carrying out the method, has a conveyor for conveying a wood board having an input end and a discharge end. A radiant heater is located above the conveyor for heating the wood board, and a rotating brush is mounted for rotation above the conveyor, for brushing the wood board after heating.   Date Recue/Date Received 2020-12-03
Patent CA-3101790-A1 (CA)
Inventor: ROUITS ELISABETH
IPC: A61P35/00
Filed: 2019-05-29
Abstract: Methods of administering immunoconjugates that bind to CD37 are provided. The methods comprise administering an anti-CD37 immunoconjugate, optionally in combination with an anti-CD20 therapy, to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.
Patent CA-3102235-A1 (CA)
Inventor: AGUERA DAMIEN
IPC: H05K7/14
Filed: 2019-06-17
Abstract: The invention relates to an interconnection system for a rack of a system of an aircraft, the rack comprising at least one shelf comprising at least one frame for receiving an electronic device, the interconnection system comprising a so-called rear panel consisting of a printed circuit board, the rear panel comprising as many sockets as there are connectors of the shelf, each socket being connected to a connector, and at least one interface for connecting a so-called side panel consisting of an electronic board, the side panel comprising an interface for connecting the so-called rear panel and connectors allowing a connection to the system of the aircraft, the printed circuit board of the rear panel allowing a set of predefined electrical connections between the connectors and the interface, the electronic board of the side panel allowing the establishment of a set of electrical connections between the interface and the connectors to the system of the aircraft.
Patent CA-3102652-A1 (CA)
Title: Appareil agricole
Inventor: PAULESSEN GEORG
IPC: B66F9/06
Filed: 2019-06-05
Abstract: Pour assurer un fonctionnement sans heurts avec une conception économique de sa structure, un appareil agricole (1) comporte un cadre (10) pourvu d'une partie médiane (10a) et peut être relié à un tracteur à l'aide d'une région de montage (19) du cadre (10). L'appareil agricole comprend en outre une première roue de support (20) supportée par un premier mécanisme de support par rapport au cadre (10) et une deuxième roue de support (30) supportée par un deuxième mécanisme de support par rapport au cadre (10). L'appareil agricole est caractérisé en ce que les premier et deuxième mécanismes de support sont accouplés l'un à l'autre et sont reliés à un accumulateur d'énergie de mettre la première roue de support (20) et la deuxième roue de support (30) en force en concordance avec le cadre (10).
Patent CA-3103926-A1 (CA)
Inventor: BURNS BRIAN MATTHEW
IPC: B29C45/76
Filed: 2019-06-05
Abstract: Systems and approaches for controlling an injection molding machine and a mold forming a mold cavity and being controlled according to an injection cycle. The systems and methods include analyzing a model of at least one of the injection molding machine, the mold, and a molten material to determine initial values for one or more control parameters of the injection molding machine, and executing a run of injection cycles at the injection molding machine; measuring operation of the injection molding machine during a particular injection cycle of the run of injection cycles; determining one or more operational parameters exceed a threshold; and upon determining that the one or more operational parameters exceed the threshold, adjusting the one or more control parameters for subsequent injection cycles of the run of injection cycles.
Patent CA-3104602-A1 (CA)
Title: Device and method for transferring rotational power with a varying distance between input and output shafts and method of using same
Inventor: SARDES AHISHAY
IPC: B60G3/18
Filed: 2019-06-30
Abstract: Device and method for providing rotational power using power transmission are disclosed. The device enables multi -dimensional and angle-agnostic displacement of the rotational power output with respect to the input location and transference of high-torque and high-speed rotational movement, while preserving maximal efficiency and quick response. The device is a transmission gear that comprises at least two gear-links in a multi-link articulated gear (MLAG). Each of the links comprising at least two gear wheels. The transmission gear further comprising a common axis adapted to allow the links to rotate freely with respect to each other about the common axis and thus to allow change of the angle between the at least two links and thereby to change the distance between the input shaft and the output shaft.
Patent CA-3105836-A1 (CA)
Inventor: MANDAWEWALA KHUSHBOO ABHISHEK
IPC: D01F8/04
Filed: 2021-01-14
Abstract: A polymeric yarn composition haying antimicrobial and/or antibacterial properties includes: (i) an herbal masterbatch in a range of 0.01%w/w to 10%w/w, and (ii) a base polymer in a range of 90%w/w to 99.99%w/w. The base polymer may include one of polybutylene terephthalate (PBT) or polyethylene terephthalate (PET), or polyamides, or polypropylene. Further, the herbal masterbatch may include: (a) an herbal component includes Neem or Turmeric or combination thereof in a range of 1%w/w to 75%w/w, and (b) a carrier polymer in a range of 25%w/w to 99%w/w. The carrier polymer may same as the base polymer and may include one of: PBT, PET, polyamides or polypropylene. To make a polymeric yam, the herbal masterbatch and the base polymer may be melted and extruded together to obtain the polymeric yam haying the herbal component in a range of 0.01% to 10% in weight of the polymeric yam.
Patent CA-3106662-A1 (CA)
Inventor: RAHBEK JENS EG
IPC: E04B1/66
Filed: 2019-07-02
Abstract: The present invention concerns an interior insulation system with moisture control for an exterior building wall, said system comprising a first insulation element adapted for abutting the interior surface of the external wall; a second insulation element abutting said first insulation element; a vapour barrier covering the interior surface of the second insulation element; a support structure below the first and second insulation elements and supporting said first and second insulation elements; wherein the support structure comprises a gutter profile having a cavity with an upper opening and at least one ventilation opening, and wherein a third insulation element is provided in at least a portion of said cavity.