baber/WOPTO huggingface dataset:
Patent CA-2498731-C (CA)
Title: .beta.-l-2'-deoxynucleosides for the treatment of resistant hbv strains and combination therapies
Inventor: STANDRING DAVID
IPC: A61K31/7076
Filed: 2003-09-15
Granted: 2012-10-30
Abstract: It has been discovered that .szlig.-L-2'-deoxynucleosides are active against drug~resistant hepatitis B virus with mutations. A method for treating lamivudine resistant HBV (M552V) in a host is provided that includes administering a .szlig.-L-2'~deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug. In addition, a method for preventing lamivudine resistant HBV (M552V) mutation from occurring in a naïve host is provided that includes administering a .szlig.-L-2'-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug. A method for preventing and/or suppressing the emergence of the HBV double mutant (L528M/M552V) in a host is also provided that includes administering a (3-L-2'-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug.
Patent CA-2498805-C (CA)
Title: Hermetically sealed load cell
Inventor: HOPKINS RANDALL K
IPC: G01L1/04
Filed: 2003-09-29
Granted: 2011-05-17
Abstract: A load cell includes a strain gage on a narrow sensing section of a beam element, on a planar outer surface facing outwardly from the median plane extending longitudinally through the cell. A cup-shaped seal cap enclosing the strain gage is laser welded onto the outer surface of the beam element to form a hermetic seal. A wiring tunnel in the load cell body leads from inside the seal cap into an electronics cavity for wires to pass from the strain gage to electronic circuitry. The load cell body and seal caps, made of stainless steel or titanium, are hermetically sealed for use in harsh environments. The seal caps have a minimal influence on strain in the sensing sections. The load cell has a low-end capacity of 5 kg or less.
Patent CA-2500296-C (CA)
Inventor: PATRICK CHRISTOPHER
IPC: G01S19/29
Filed: 2003-10-17
Granted: 2012-10-16
Abstract: A method of and system for estimating a parameter of a local maxima or minima of a correlation function derived from a received signal . An interpolated local maxima or minima is determined. An interpolation offset is then derived, comprising a deviation between locations of the interpolated and sampled local maxima or minima of the function. An estimate of the parameter is derived from the interpolation offset.
Patent CA-2501526-C (CA)
Title: Dispositif d'occlusion vasculaire avec revetement elastomerique bioresorbable
Inventor: JONES DONALD K
IPC: A61B17/00
Filed: 2005-03-21
Granted: 2013-07-16
Abstract: Un dispositif d'occlusion vasculaire comprend une structure de support embolique, comme une spirale embolique, ayant un revêtement élastomérique biorésorbable disposé sur la surface de la structure de support qui sert à promouvoir la croissance de tissu contrôlée dans la structure de support embolique.
Patent CA-2507590-C (CA)
Inventor: MULLET WILLIS J
IPC: E05F15/20
Filed: 2003-11-10
Granted: 2009-06-02
Abstract: A system for signaling the position of a movable barrier includes a movable barrier; a motor coupled to the movable barrier for moving the movable barrier between limit positions; a position detection device that monitors the movable barrier to generate a barrier position signal; and an indication device that receives the barrier position signal and indicate a position of the movable barrier relative to the limit positions. The system also includes an operation mechanism for controlling the motor and at least one transmitter device which generates a transmission signal received by the operator mechanism to energize the motor. The system further includes a blocking switch which generates a blocking Signal received by the operator mechanism to prevent receipt of a transmission signal from a device other than one associated with the indication device.
Patent CA-2508139-C (CA)
Title: Mutants d'echappement du virus de la maladie de newcastle en tant que vaccins marqueurs
Inventor: ALEXANDER DENNIS JOHN
IPC: C12N7/00
Filed: 2003-12-03
Granted: 2009-09-22
Abstract: L'invention concerne un vaccin contre la maladie de Newcastle renermant un ou plusieurs immunogènes mutants de la souche du virus de la maladie de Newcastle appelée NDW. L'immunogène mutant est dépourvu du site de liaison antigénique sur la glycoprotéine F que reconnaît l'anticorps monoclonal mAb 54. L'invention concerne également des kits de réactifs et des procédés d'essai qui aident à faire la distinction entre des volailles vaccinées et des volailles susceptibles d'être infectées par le virus de la maladie de Newcastle de type sauvage.
Patent CA-2509635-C (CA)
Inventor: KEISER BRUCE A
IPC: D21H21/14
Filed: 1998-09-17
Granted: 2007-11-20
Abstract: The invention comprises a borosilicate retention aid composition and a method for improving the production of paper by addition of the borosilicate. The borosilicate may be utilized in conjunction with a high molecular weight synthetic flocculant and/or starch, with or without the addition of a cationic coagulant. The borosilicate material is preferably a colloidal borosilicate. Methods for the preparation of the borosilicate material are disclosed.
Patent CA-2510152-C (CA)
Title: Temporary, pharmacologically-inactive dental coating for the in situ protection of dental therapeutic agents from saliva and abrasion from chewing
Inventor: SYMINGTON JOHN MARSTON
IPC: A61K9/00
Filed: 2003-12-16
Granted: 2013-04-02
Abstract: Topical application of a pharmacologically-inactive, inert polymeric solution to teeth affords a temporary, protective barrier for pharmacologically-active compounds that have been previously applied topically to the tooth surfaces for caries reduction. In a method of use, an aqueous dispersion polymethylmethacrylate (PMMA) and a suitable plasticizer are applied topically to the tooth surface immediately after the topical application of chlorhexidine or fluoride. The inert coating thus formed is distinct from any pharmacologically-active substance, and remains on the tooth surface until abraded by the chewing of hard foods. In a composition of matter, the solution contains ammonio methacrylate copolymer, type B USP/NF of between 20% and 35%  w/w; triethyl citrate USP/NF of between 1% and 10% w/w; and purified water of between 60% and 70% w/w. The ammonio methacrylate copolymer is preferably EUDRAGIT RS 30 D brand available form Rohm GmbH.
Patent CA-2512610-C (CA)
Inventor: GREENBERG ROY K
IPC: A61F2/06
Filed: 2004-01-13
Granted: 2008-12-23
Abstract: An endoluminal prosthesis (40) comprises a prosthetic trunk (42) comprising a trunk lumen extending therethrough, a wall, and an anastomosis in the wall, wherein the prosthetic trunk has a circumference. The endoluminal prosthesis further comprises a prosthetic branch (44) comprising a branch lumen extending therethrough the anastomosis (46). The prosthetic branch is disposed longitudinally along and circumferentially about the prosthetic trunk.
Patent CA-2514386-C (CA)
Inventor: BALL WILLIAM T
IPC: E03C1/042
Filed: 2005-07-29
Granted: 2008-10-07
Abstract: Une prise d'eau murale ayant un tube d'entrée passant à travers un mur ayant une surface extérieure et intérieure et comprenant une rosace reçue par le tube d'entrée pour être placé contre la surface intérieure du mur à l'aide de griffes flexibles qui s'étendent radialement à partir d'un centre pour fixer la prise d'eau contre la surface extérieure du mur.
Patent CA-2518470-C (CA)
Inventor: HWANG SHYH-YUAN HENRY
IPC: C07C6/00
Filed: 2004-03-19
Granted: 2010-09-21
Abstract: La présente invention concerne des procédés améliorés, d'une part pour la production de composés aromatiques alkyliques en utilisant des catalyseurs zéolites, et d'autre part pour la réactivation périodique sur site des catalyseurs zéolites au moins en partie désactivés. Les traitements de l'invention se font généralement dans une tranche de réaction chargée de catalyseurs, le composé aromatique alkylique voulu étant produit à partir de composés aromatiques de base et d'oléfines, puis dans une tranche de séparation dans laquelle le produit voulu est isolé et récupéré. Les réactions d'alkylation, de transalkylation, et/ou d'isomérisation qui se produisent dans la tranche de réaction s'exécute en phase liquide ou en phase liquide partielle au-dessus des catalyseurs zéolites. Une partie au moins des catalyseurs zéolites employés dans la tranche de réaction est réactivée sur site, périodique ou lorsqu'on l'estime nécessaire, en prenant les catalyseurs désactivés, à température élevée et sensiblement en l'absence de produit de base oléfinique, et en les mettant en contact avec un courant de désorption aromatique comprenant le composé aromatique de base, le produit aromatique alkylique voulu, les sous-produits formés dans le traitement, ou certains de leurs mélanges, de façon à rétablir leur activité.
Patent CA-2518662-C (CA)
Title: Diagnosis of gynecological neoplasms by detecting the levels of oviduct-specific glycoprotein
Inventor: AUERSPERG NELLY
IPC: G01N33/574
Filed: 2004-03-11
Granted: 2014-06-17
Abstract: The present invention provides a method for detecting cancer in a patient. A  sample from the patient is provided, and the level of oviduct-specific glycoprotein (OGP) in the sample is determined and compared to a control sample. Increased levels of OGP in the sample as compared to the control indicates that the patient has cancer. In one aspect, the cancer is a gynecological cancer, such as ovarian cancer. Kits for conducting the methods of the invention are also provided.
Patent CA-2518821-C (CA)
Inventor: ENSINGER WILFRIED
IPC: E06B3/667
Filed: 2004-03-13
Granted: 2011-07-05
Abstract: In order to provide a spacer profile for an insulated glazing unit, which profile has a cross-section based on a rectangular shape, is provided with two parallel spaced side walls which, when said insulated glazing unit is assembled, will be placed against the panes of glass to be kept apart from each other, and is further provided with first and second transverse walls which extend between said side walls and of which the first will be adjacent to the edge of the glazing unit and the second will face the space between the panes, with the intention of enabling simple handling of said profile when assembling the spacer frame whilst maintaining a high absorptive capacity for water vapor, it is proposed that said spacer profile comprises a binder matrix and, embedded therein, a particulate adsorbent material for water vapor, and that the binder matrix is permeable to water vapor.
Patent CA-2519276-C (CA)
Inventor: SAITO KAZUKI
IPC: H01R13/193
Filed: 2004-03-12
Granted: 2008-09-09
Abstract: A connector for switching between the states of the connection and non-connection to a mating connector by a cam mechanism (6) movably installed in insulators (2, 3), wherein the cam mechanism comprises a first cam (6a) and a second cam (6b). The first cam is rotatable about an axis, slidable between first and second positions in a direction parallel with the axis, and energized toward the first position by an elastic member (8). The second cam is rotated in conjunction with the first cam to provide either of the connected state and non-connected state according to a rotating angle. The first cam comprises a locked part (6a2) engaged with the lock part (3b3) of the insulator in the rotating direction thereof when positioned at the first position and disengaged from the lock part when positioned at the second position.
Patent CA-2521768-C (CA)
Inventor: HONKANEN ANNIINA
IPC: A23L33/00
Filed: 2004-04-22
Granted: 2013-08-06
Abstract: The present invention relates to edible products with masked bitter, sour and/or astringent taste. The new products comprise a sweetening agent and from 0.2 to 25 % by weight plant sterol ester, wherein the amount of sweetening agent is reduced as compared to a regular product.
Patent CA-2523777-C (CA)
Inventor: BURWELL PHILLIP
IPC: A61N5/06
Filed: 2004-03-12
Granted: 2016-05-10
Abstract: Light generating devices for illuminating portions of vascular tissue, to render photodynamic therapy. In one embodiment, a light source array preferably including a plurality of light emitting diodes, a focusing lens, and a light diffusing element are included in a distal end of a catheter. A  balloon is optionally provided to interrupt blood flow that can block the transmission of light, and to center the apparatus in a blood vessel. Optical fibers optionally direct light from the light source to the diffusing element.  The light source array can have a radial or linear configuration and can produce more than one wavelength of light for activating different photoreactive agents. Linear light source elements are particularly useful to treat elongate portions of tissue in a vessel. One embodiment intended for use with a conventional balloon catheter integrates light sources into a guidewire.
Patent CA-2527141-C (CA)
Title: Polyhydroxy phenols and their use in binding p-selectin
Inventor: BIESSEN ERIK ANNA LEONARDUS
IPC: C07C229/16
Filed: 2004-05-07
Granted: 2012-03-27
Abstract: Polyhydroxy phenols, which are non-peptidic mimetics of galloyl peptides, and a process for the preparation of gallic acid derivatives using a gallic-acid providing moiety are provided as well as polyhydroxy phenol-containing pharmaceutical and nutraceutical compositions. The use of polyhydroxy phenols as a medicament and especially for the manufacture of a medicament for the prevention, treatment or diagnosis of a disease or a condition, wherein P-selectin is involved, is provided. The same compounds can also be used as targeting tools to P-selectin expressing cells or tissues in a composition, further comprising an active compound in a vehicle.
Patent CA-2527261-C (CA)
Inventor: SKILLIN CLIFFORD WAYNE
IPC: B65D47/08
Filed: 2005-11-17
Granted: 2012-10-02
Abstract: Un capuchon de distribution pour un récipient pour distribuer un liquide contenu dans celui-ci, comprenant un corps de fermeture adapté pour être monté sur le récipient. Le corps du capuchon a une paroi supérieure et une jupe dépendant de celle-ci vers le bas et un orifice de distribution positionné sur celle-ci. Une structure tubulaire de modulation d'écoulement dépend vers le bas à partir de la paroi supérieure du corps du capuchon. La structure tubulaire de modulation d'écoulement a une surface intérieure configurée et disposée pour contrôler l'écoulement de liquide à travers l'orifice de distribution et comprend au moins une fente capillaire dépendante. Éventuellement, le capuchon de distribution comprend en outre une structure de capture synérèse dépendante vers le bas à partir de la paroi supérieure pour empêcher le fluide de synérèse de s'écouler à travers l'orifice de distribution lors de la distribution du liquide contenu dans le récipient.
Patent CA-2531972-C (CA)
Inventor: STOLOWITZ MARK L
IPC: H01J49/40
Filed: 2003-07-14
Granted: 2011-11-29
Abstract: La présente invention concerne des dispositifs de présentation d'échantillon utilisés pour effectuer des mesures analytiques. Ces dispositifs ont été conçus pour permettre divers aspects de la manutention de liquides, tels que la conservation, le stockage, le transport, la concentration, le positionnement et le transfert. En outre, ces dispositifs permettent d'améliorer la détection et la caractérisation d'analytes. Lesdits dispositifs de présentation d'échantillon comprennent au moins un substrat possédant une pluralité de zones de mouillabilité différente. Cette invention a également pour objet des procédés d'analyse d'échantillons au moyen du dispositif de présentation d'échantillon susmentionné, ainsi que des procédés de conception des dispositifs de présentation d'échantillon.
Patent CA-2533099-C (CA)
Inventor: SNAGEL PAUL
IPC: E01F9/06
Filed: 2004-05-26
Granted: 2009-01-27
Abstract: A pavement marker includes a base (12) and at least one lens (17, 18) with retroreflective areas aligned to reflect headlights back toward a vehicle for producing a nighttime signal. The lens and/or the base are formed from resins that include a fluorescent material. At least a portion of the lens is free of the retroreflective areas to that the fluorescent material of the lens and/or the base produces a daytime signal emitted from or through the lens.
Patent CA-2533590-C (CA)
Inventor: MILLER CHERYL C
IPC: A23K1/18
Filed: 2004-09-03
Granted: 2013-03-12
Abstract: This invention is directed generally to compositions (including foods, supplements, treats, toys, etc.) for animal consumption, particularly compositions that tend to aid in weight loss or reduction in weight gain, and particularly compositions that comprise one or more medium chain fatty acid triglycerides ("MCT"). This invention also is directed generally to methods for using such compositions. This invention is further directed generally to processes for making such compositions.
Patent CA-2535570-C (CA)
Inventor: URMEY KIRK DAVID
IPC: B65D1/02
Filed: 1998-01-09
Granted: 2008-08-19
Abstract: A thermoplastic bottle, comprising: an asymmetric body means responsive to internal pressure by stretching in a vertical plane; and a bottom closure base means on the body means, the base means having an odd number of at least five projecting feet, one of the feet being aligned with the vertical plane of stretching so that at least three of the at least five feet remain in a plane of support during stretching in the vertical plane.
Patent CA-2546586-C (CA)
Inventor: VOLLERTSEN FRANK
IPC: B23K26/10
Filed: 2004-12-10
Granted: 2010-03-02
Abstract: The invention relates to an orbital welding device for mobile use in order to join a first pipe end (1) and a second pipe end (2) along a circumferential joint (3) by means of at least one weld seam (4), particularly for producing a pipeline (5) to be placed on land. The inventive device comprises a guide ring (6), which can be oriented toward the first pipe end (1) and the circumferential joint (3), and an orbital carriage (7) that can be motor-displaced along the guide ring (6) via an advancing device (8). On the orbital carriage (7), a laser welding head (12) for directing a laser beam (10) into a laser welding zone (13) is mounted in a manner that enables it to be oriented toward the circumferential joint (3) whereby enabling the production of the weld seam (4) along the circumferential joint (3) by displacing the orbital carriage (7). The laser beam (10) is produced by a high-power fiber laser beam source (9) located, in particular, on a mobile transport vehicle (35) while being situated at a distance from the orbital carriage (7), is guided by light guide (11) passing though a tube bundle (50) to the orbital carriage (7) and then supplied to the welding head (12). A significant advantage of the invention resides in the fact that the joining of two pipe ends by means of only one single welding process during a short period of time is made possible in the field with autonomous operation.
Patent CA-2552904-C (CA)
Inventor: BEST BRUNO
IPC: G01V1/145
Filed: 2005-01-21
Granted: 2014-05-13
Abstract: Seismic source comprising an actuator having a rotary part (104) and a reciprocative part (105), conversion means (109) in the form of corrugated surfaces to convert a rotation of the rotary part (104) into a reciprocal movement of the reciprocative part (105), and a vibrator body (106) that is connected to the reciprocative part (105) of the actuator by means of a spring (107).
Patent CA-2553123-C (CA)
Inventor: BARTON JOHN A
IPC: B65D81/05
Filed: 2005-01-07
Granted: 2009-04-14
Abstract: A system and method for a packaging system for the shipment of high explosive components is described. One or more explosive devices (20) are positioned in a tubing assembly having opposed ends and a thick wall of relatively low-density fibrous material, e.g. rolled paper tube. An impact absorbing element is positioned at each end of the tube (36). The impact absorbing element may include an end cap (38) positioned within each end of the tube, and a cushion formed of partial tubes (44) and an end cap (38). The complete assembly is sized to fit and be held in position by a standard shipping container.  Multiple perforating charges in a tubing assembly may face opposite sides of a charge divider (32). Shaped charges may have their concave openings filled with a jet interrupter (42), e.g. sand. Circular charges may include heat releasable fasteners, e.g. nylon screws, which allow the charges to separate in case of fire.
Patent CA-2553417-C (CA)
Inventor: KENNEDY THOMAS DUANE
IPC: B32B27/28
Filed: 1995-06-05
Granted: 2008-11-18
Abstract: Films containing a sealant layer composition comprising: (1) polyethylene homopolymer, and ethylene/ alpha-olefin copolymer, ethylene vinyl acetate copolymer, and ethylene/ acrylate copolymer; and (2) elastomer, plastomer, ionomer, and carboxyl-modified polyethylene; when sealed to another outer film layer comprising at least one member selected from the group consisting of ionomer, ethylene/acid copolymer, ethylene/vinyl acetate copolymer and ethylene/acrylate copolymer, have been discovered to provide a seal strength comparable to an ionomer to ionomer seal.
Patent CA-2556116-C (CA)
Inventor: CHINNADURAI MANOKAR
IPC: G01D3/10
Filed: 2006-08-11
Granted: 2013-07-30
Abstract: Exemplary embodiments of an improved scanning tool are disclosed. In various embodiments, the improved scanning tool uses at least one input capable of providing an indication of a desired operating mode of use; and an electronic control system configured to sense the desired operating mode indication, then select one of a plurality of operating system modes based on the desired operating mode indication.
Patent CA-2559133-C (CA)
Title: Apparatus and system for controlling signal filtering
Inventor: CHAN FRANK SIU HONG
IPC: H04M11/06
Filed: 2006-09-08
Granted: 2011-10-25
Abstract: According to embodiments of the present invention, there is provided an apparatus and system for controlling signal filtering. According to some non-limiting embodiments, a selective filtering apparatus is provided. The selective filtering apparatus comprises an input interface connectable to a source of a composite signal within a first frequency range and a filtering device, coupled to the input interface. The filtering device comprises a filter and an output interface, the filter being operable to filter the composite signal and output an output signal within a second frequency range, the second frequency range being a subset of the first frequency range; the output interface being connectable to at least a portion of an in-premises telephone wiring. The selective filtering apparatus further comprises a triggering module being operable to cause the output interface to selectively output one of the output signal and the composite signal responsive to detection of a triggering event.
Patent CA-2559831-C (CA)
Title: Ageing-resistant copolymers comprising polyamide blocks and polyether blocks
Inventor: MALET FREDERIC
IPC: C08K5/103
Filed: 2006-09-18
Granted: 2010-06-22
Abstract: The present invention relates to a copolymer composition comprising homo- or copolyamide polyamide blocks and polyether blocks and further comprising: a) 3 000 to 8 000 ppm of at least one phenolic antioxidant; b) 0 to 5000 ppm of at least one phosphorus or sulphur based antioxidant; c) 0 to 5000 ppm of at least one UV absorber;and d) 200 to 3000 ppm of at least one methylated HALS meaning hindered amine light stabilizer and/or 200 to 800 ppm of at least one nonmethylated HALS; ppm meaning parts per million of total composition. The compositions are useful in mainufacturing articles, such as shoe sole.
Patent CA-2561647-C (CA)
Title: Door locking system conversion adapter
Inventor: BROWN GERALD L
IPC: E05B63/14
Filed: 2005-03-30
Granted: 2012-11-06
Abstract: The present invention features a system and method for operating or operably connecting an American locking cylinder with a Profile mortise lock, wherein the American locking cylinder functions with the Profile mortise lock in place of a Profile locking cylinder. Essentially, the present invention provides a door lock cylinder conversion adapter that converts an American cylinder to be operable with a Profile mortise lock.