baber/WOPTO huggingface dataset:
Patent EP-1930428-B1 (EP)
Inventor: IDIRIS ALIMJAN
IPC: C12N15/09
Filed: 2006-07-31
Granted: 2010-12-01
Abstract: 酵母を宿主とした形質転換体における異種タンパク質の生産効率を向上させる。
　シゾサッカロミセス・ポンベ（Schizosaccharomyces　pombe）のプロテアーゼ関連遺伝子群（特にメタロプロテアーゼ遺伝子群とセリンプロテアーゼ遺伝子群）から選ばれる１種以上の遺伝子を削除または不活性化する、外来遺伝子を発現させるための宿主の構築方法、上記遺伝子を削除または不活性化した宿主、その宿主に外来遺伝子を導入してなる形質転換体、および、その形質転換体を用いた異種タンパク質の製造方法。
　プロテアーゼ関連遺伝子としては、psp3（SPAC1006.01）、sxa2（SPAC1296.03c）、ppp51（SPAC22G7.01c）およびppp52（SPBC18A7.01）からなる群から選ばれる１種以上の遺伝子、または、メタロプロテアーゼ遺伝子群およびセリンプロテアーゼ遺伝子群からなる群から選ばれる２種以上の遺伝子であることが好ましい。特に、psp3（SPAC1006.01）、isp6(SPAC4A8.04)、ppp53(SPAP14E8.04)の少なくとも３種が好ましく、さらにその３種にppp16(SPBC1711.12)を加えた４種、さらにそれにppp22(SPBC14C8.03)を加えた５種、の遺伝子削除または不活性化した宿主が好ましい。
Patent EP-1919321-B1 (EP)
Inventor: SOKOLOWSKI SUSAN L C O NIKE INC
IPC: A43B1/04
Filed: 2006-07-14
Granted: 2012-08-22
Abstract: L'invention concerne des chaussures qui comprennent un élément supérieur textile et un revêtement extérieur constitué d'un matériau textile tricoté, le revêtement extérieur comprenant une région présentant des nervures de stabilité et une seconde région sans nervure. La ou les régions comprenant des nervures de stabilité peuvent être situées, par exemple, le long d'un côté mi-pied latéral de l'élément supérieur ; le long d'une partie d'avant-pied de l'élément supérieur ; et/ou le long d'un côté mi-pied central de l'élément supérieur. D'autres chaussures comprennent un élément supérieur présentant des  éléments textiles extérieurs et intérieurs assemblés sans couture au niveau de l'ouverture réceptrice du pied de l'élément supérieur. La surface extérieure de cet élément supérieur peut également comprendre une ou plusieurs régions équipées des structures de stabilité. Les techniques d'assemblage textile sans couture permettent d'obtenir une jointure lisse, non encombrante et imperrespirante qui ne nécessite pas l'utilisation d'épaisses couches de matériau textile en contact avec le pied de l'utilisateur ou adjacentes audit pied.
Patent EP-1945846-B1 (EP)
Inventor: CIABATTINI ALBERTO
IPC: D06C19/00
Filed: 2006-11-08
Granted: 2010-01-06
Abstract: The machine has a path for passage of fabric in rope form (T) with a transfer system (7), such as a pneumatic system. Along the path said fabric (T) passes through a plurality of accumulation areas (3A, 3B; 3C, 3D; 3E, 3F) with alternate motion.
Patent EP-1945995-B1 (EP)
Inventor: FAYOLLAS PHILIPPE
IPC: F16M11/04
Filed: 2006-11-08
Granted: 2010-03-17
Abstract: System for positioning a component on a frame relative to a reference. It comprises a ball assembly (4), composed of a rod (6), a ball (8) fixed to the rod (6) and a ball joint clamping system (10, 12) mounted on the rod to fix the ball assembly relative to the component; a vee assembly composed of a rod (16), a vee (18) fixed to the rod (16) and a ball joint clamping system (20, 22) mounted on the rod to fix the vee assembly relative to the frame; an elastic connecting element (26) to keep the ball (8) in contact with the vee (18).
Patent EP-1888045-B1 (EP)
Inventor: SOULA GERARD
IPC: A61K9/50
Filed: 2006-05-24
Granted: 2010-09-08
Abstract: The invention relates to pharmaceutical compositions of acetylsalicylic acid-based microcapsules to selectively inhibit the COX in the portal vein and/or in the liver to reduce the production of thromboxane. Further, the pharmaceutical composition minimizes COX inhibition in the systemic circulation to optimize the inhibition of platelet aggregation. Certain embodiments also address methods of prevention and/or treatment of these diseases, using these oral compositions such as enhancing the safety of antithrombotic treatments. Other embodiments contemplate oral pharmaceutical compositions that combine acetylsalicylic acid with anti-platelet aggregation drugs, without inducing gastric side effects.
Patent EP-2004036-B1 (EP)
Inventor: MOLNAR GREGORY F
IPC: A61B5/375
Filed: 2006-12-05
Granted: 2011-07-20
Abstract: A method, apparatus, and system for treating patients suffering from movement disorders having the ability to determine one or more biomarkers indicative of a disease state. In some embodiments, the biomarker may be used as a closed-loop feedback signal to control the delivery of therapy (such as electrical stimulation or drug therapy), and which may also be used as an indication of therapy effectiveness. One embodiment uses electrodes placed in the brain to measure EEG or local field potential (LFP) signals, from which the one or more biomarkers may be determined.
Patent EP-1971585-B1 (EP)
Inventor: TRINKA PETER
IPC: C07D295/088
Filed: 2006-12-08
Granted: 2011-03-09
Abstract: The present invention relates to a process for the preparation of {2-[4-(alpha-phenyl-p-chlorobenzyl)-piperazin-1-yl]-ethoxy}-acetic acid-N,N-dimethylamide of the Formula (I) and enantiomers thereof. The compound of the Formula (I) or enantiomers thereof are important pharmaceutical intermediates suitable for direct transformation into non-sedating antihistamine type pharmaceutical active ingredients cetirizine and levocetirizine.
Patent EP-1818391-B1 (EP)
Inventor: SEIDEL GEORGE E
IPC: A61D19/02
Filed: 1998-12-31
Granted: 2015-06-17
Abstract: Artificial Insemination is achieved for sexed mammalian offspring in a commercially practical manner and with dosages of insemination sperm which were not previously thought to be practical for commercial implementation. Improved insemination systems particularly adapted to use for sex-selected sperm sorting include systems which achieve superovulation and then multiple embryo production with sexed embryos. These systems combine with other techniques, including techniques for enhanced sheath fluid (3) and other strategies which minimize stress on the sperm cells (18), and potentially, a 2.9 percent sodium citrate sheath solution for bovine species and a hepes bovine gamete media for equine species. Improved collection systems (14) and techniques for the process are describeb so that commercial application of sperm samples as well as the resulting animals may now be achieved in the field.
Patent EP-1808216-B1 (EP)
Inventor: VINCENT JEAN LOUISE
IPC: F17C7/02
Filed: 2005-06-27
Granted: 2010-06-16
Abstract: A method of dispensing an elevated pressure high purity fluid from an outer vessel having an outlet controlled by a valve, comprising; 
providing an outer vessel having an inner vessel containing a purification media connected to the outlet and an inlet of the inner vessel has a fluid flow control device that only allows high purity fluid to flow from an interior of the outer vessel to the outlet; 
opening the valve to flow elevated pressure high purity fluid through the fluid flow control device and through the purification media; 
purifying the high purity fluid of contaminants contained in the high purity fluid by interaction with the purification media; 
dispensing the high purity fluid through the outlet of the outer vessel; 
wherein the first portion of the high purity fluid dispensed from the inner vessel is separated from the high purity fluid dispensed after the first portion.
Patent EP-1915937-B1 (EP)
Inventor: COURTNEY STEPHEN BENJAMIN
IPC: A47L9/24
Filed: 2003-07-18
Granted: 2010-03-17
Abstract: A surface treating appliance (200), such as a vacuum cleaner, comprises a user-operable handle (212), a main body (210), a surface treating head (230) and a support assembly (220). The support assembly (220) is rollably mounted on the main body (210) for allowing the main body (210) to be rolled along a surface by means of the handle (212). The surface treating head (230) is connected to the main body by a yoke (235) and at least a part of the yoke (235) carries a fluid flow.
Patent EP-1923675-B1 (EP)
Inventor: ZWIKKER JAN MARINUS
IPC: G01F1/84
Filed: 2007-10-10
Granted: 2010-07-28
Abstract: Coriolis mass flowmeter comprising a flow tube, at least one tube position sensor provided with a light source and with a light detector for receiving light from the light source, and drive means for causing the tube to move about an axis, the above being arranged such that the tube or a projection fastened to the tube, for example a vane, moves through a light path between the light source and the light detector, wherein a first screen with a first light-transmitting opening is placed at the side of the light source and a second screen with a second light-transmitting opening is placed at the side of the light detector, wherein the first and the second opening are identical and are correspondingly oriented, and wherein the openings are mutually parallel and aligned so as to form a prismatic light beam on the detector.
Patent EP-1868355-B1 (EP)
Inventor: SICART JULIEN
IPC: H04L29/08
Filed: 2007-06-11
Granted: 2012-01-18
Abstract: The method involves receiving an access request, comprising a source address, from a terminal e.g. personal computer (30). The address and an identifier (ID-USR1) of a user account is obtained from the request. An association request from a terminal (10) is received. A gateway address and an identifier (MAC-10) of the terminal (10) is obtained from the association request. Another gateway address is obtained from the source address. The gateway addresses are compared, and the identifier of the terminal (10) is associated to the identifier of the account when the addresses are equal. Independent claims are also included for the following: (1) a device for associating an identifier of a terminal to an identifier of a user account (2) a computer program comprising instructions for implementing a terminal and user account identifiers associating method (3) a storage medium readable by a computer for storing the computer program comprising instructions for implementing a terminal and user account identifiers associating method.
Patent EP-1873096-B1 (EP)
Inventor: KOENIG KLAUS
IPC: B65H1/26
Filed: 2007-06-27
Granted: 2010-01-20
Abstract: The device has an outlet device (A) with a pile (1) of flat objects e.g. letter, which are standing at an edge. A feeding unit (F1) feeds the flat objects in an upright position towards the outlet device. Another pile (2) of flat objects, which are standing at the edge, is arranged on another feeding unit (H), which is formed and arranged above the feeding unit (F1) such that the pile (2) is movable to the end of the pile (1) or at the outlet device without contacting the feeding unit (F1) and is loadable at the feeding unit (F1).
Patent EP-1895066-B1 (EP)
Inventor: DROSTE STEFAN
IPC: E03D13/00
Filed: 2007-07-30
Granted: 2009-10-07
Abstract: The device has an enclosure (1) assigned to an inspection opening of a flush rinser or flush cistern. An operating unit (3) protrudes forward in a starting position opposite to a frame-shaped screen (4), and is provided with a plate-shaped pusher (5) at its front side. The pusher protrudes laterally opposite to a lateral surface of the operating unit. The distance of a narrow side of the pusher to the lateral surface of the operating unit is larger than the distance of a rear side of the pusher to a front side (4.1) of the screen in the starting position of the operating unit.
Patent EP-2055214-B1 (EP)
Inventor: WUETHRICH CHRISTOPH
IPC: A47J31/36
Filed: 2007-10-29
Granted: 2010-08-11
Abstract: The unit (1) has a brewing cylinder (6) with a cylindrical bore and upper and lower pistons (3, 4). The cylinder and the pistons are held in a frame (2) and are driven by a spindle (9) including a trapezoidal thread (8). A coffee powder feeding device fills a brewing chamber with coffee powder. A stripping element (19) serves to strip off the residual coffee powder that is discharged from the chamber through the lower piston after the brewing process. The spindle is supported by supporting units (31) on a region opposite to a threaded part (7a), where the units are attached to the frame.
Patent EP-1930562-B1 (EP)
Inventor: OISHI AKIFUMI
IPC: F16H37/08
Filed: 2007-11-20
Granted: 2009-04-15
Abstract: To provide a straddle type vehicle such as a motorcycle with a four-stroke engine and a belt type CVT, in which an axial length is restricted, a body frame (2) comprises a down frame (4) extending vertically. An engine unit (12) comprises a four-stroke engine (13), a belt type CVT, a clutch, and a crank case (51). A cylinder is arranged rearwardly of the down frame (4) with an axis thereof extending vertically. The clutch is provided between a secondary sheave shaft (38) and an output shaft. The crank case (51) is formed with an oil reservoir portion (51b), which is disposed below a crank shaft (20) to store a lubricating oil. The oil reservoir portion (51b) is formed so that a rear end thereof is positioned rearwardly of a front end of a secondary sheave. The crank shaft (20) is arranged so that an axis thereof is positioned below an axis of the secondary sheave shaft (38).
Patent EP-1849386-B1 (EP)
Inventor: FRIGERI PATRIZIO
IPC: A47J31/40
Filed: 2007-03-28
Granted: 2008-10-22
Abstract: The coffee maker (1) has a delivery member including a screw shaft (10) provided with a flight (13) for feeding a coffee powder i.e. caffeine, into and out of a brewing zone (24) in a common direction. An extraction zone (25) is in downstream of the brewing zone in which the powder is compacted and the essence of the powder is extracted, where the screw shaft extends along the brewing zone and along the extraction zone. A pitch of the flight in the region of the extraction zone is smaller than another pitch of the flight in the region of the brewing zone. An independent claim is also included for a method for the preparation of hot beverages.
Patent EP-2141800-B1 (EP)
Inventor: ISHIKAWA HIROYOSHI
IPC: H03F1/32
Filed: 2007-03-28
Granted: 2012-08-22
Abstract: 送信対象の入力信号のバーストによる送信増幅器のバースト歪を補償する歪補正制御装置であって；前記バースト歪の逆特性を有する歪補正係数を記憶する保持手段と；前記入力信号有無の切り替わりを知らせるバースト情報の受信を契機に、前記保持手段から読み出された前記歪補正係数を前記入力信号に乗算または加算する手段と；前記入力信号と、前の前記歪補正係数と、前記送信増幅器の出力信号としてフィードバックされる信号とに基づいて、適応アルゴリズムにより前記歪補正係数を更新し、更新した前記歪補正係数を前記保持手段に入力する更新手段とを備える。
Patent EP-2027313-B1 (EP)
Inventor: SCHARENBERG ANDREW M
IPC: C40B40/02
Filed: 2007-03-27
Granted: 2012-05-16
Abstract: Conformément à des aspects particuliers donnés à titre d'exemple, des propriétés de liaison et de clivage de site cible ADN d'endonucléases ciblées natives, variantes ou modifiées (HE) (par exemple, LAGLIDAG (LHE), HNH, His-Cys Box, GIY-YIG, I-SspI-type, et fusions, mutéines ou variantes de ces derniers ) en solution sont récapitulées sur la surface cellulaire (par exemple, comme évalué par analyse de cytométrie de flux) pour prévoir de nouvelles cellules exprimant une ou plusieurs surfaces cellulaires HE (par exemple, exprimant une ou plusieurs liaisons HE et spécificités de clivage), de nouvelles bibliothèques de cellules et de procédés à haut rendement pour l'évaluation de liaison de sites cibles, clivage de sites cibles. L'analyse rapide de HE et d'interactions LHE-ADN sur la surface cellullaire avec des options de tri concurrentes fournit un tri de bibliothèques à haut rendement permettant une identification rapide, une analyse et un isolement de nouveaux HE ou LHE ayant de nouvelles spécificités séquentielles. De telles nouvelles spécificités séquentielles obtenues par lesdits procédés fournissent de nouveaux procédés d'introduction d'événements de clivage de brins d'ADN ciblés, et de nouveaux procédés d'immunoprécipitation de la chromatine.
Patent EP-2035383-B1 (EP)
Inventor: OSTERMAIER JOHN J
IPC: C07F5/02
Filed: 2007-06-21
Granted: 2011-02-16
Abstract: A process for producing solid triphenylboron-pyridine (TPBP) spherical particles by separately feeding into a vigorously agitated reaction zone (i) a stream of pyridine and a (ii) stream comprising a solution of sodium hydroxide adduct of triphenylboron (TPBA) whereby the total concentration of TPBA in the combined feed streams is in the range of from 1 wt % to 6 wt %, and simultaneously removing a product stream from said reaction zone and recovering the triphenylboron-pyridine (TPBP) particles.
Patent EP-2049362-B1 (EP)
Inventor: PUDENZ CHRISTIAN
IPC: B60N2/58
Filed: 2007-08-31
Granted: 2011-04-06
Abstract: L'invention concerne un siège de véhicule climatisé, comprenant une partie de rembourrage de dossier ou siège inférieure (3) imperméable à l'air, une couche intermédiaire laissant passer l'air et un revêtement de rembourrage (6, 7, 8) balayé par l'air du côté de la couche intermédiaire, ce dernier étant divisé par des cloisonnements (13, 14) ancrés sur la partie de rembourrage imperméable à l'air, en des zones de rembourrage délimitées les unes par rapport aux autres, des ponts aériens (15) s'étendant transversalement aux cloisonnements étant prévus pour relier la couche intermédiaire entre les zones de rembourrage individuelles. Selon l'invention, une ventilation libre du siège et une fixation sûre et durable des cloisonnements sont obtenues, de manière simple du point de vue de la technique de fabrication et sans altérer le confort du siège, grâce à la conception plus étroite des ponts aériens (15) dans la direction longitudinale des cloisonnements (13, 14) que les zones de bord côté cloisonnement de la couche intermédiaire, et grâce à l'ancrage des cloisonnements sans couche intermédiaire des ponts aériens dans des sections de paroi (16) de la partie de rembourrage (3) adjacentes à ces derniers des deux côtés.
Patent EP-2174034-B1 (EP)
Inventor: CRIPPA CRISTIAN
IPC: F16D65/092
Filed: 2007-06-27
Granted: 2010-12-29
Abstract: A pad (20) for disc brakes comprises a plate (22) acting as the support for a friction material layer (24). The plate (22) extends past the friction material layer (24) at least at a radially outer portion (E) of the pad. At least one load (30a, 30b) is applied to the plate (22) and fixed thereto by means of clinching. This load changes the mass of at least one portion of the plate such as to obtain an inertia of the pad which substantially avoids the vibrations of the pad during the braking action which are suitable to cause noisiness of the disc brake. The load (30a, 30b) comprises at least one projection (32) suitable to be clinched to fix the load to the plate. The projection (32) is inserted within a hole (34) of the plate and clinched.
Patent EP-2102522-B1 (EP)
Inventor: KT PROJEKTENTWICKLUNGS-GMBH
IPC: F16D65/00
Filed: 2007-11-05
Granted: 2010-04-21
Abstract: The invention relates to a brake dust collector (10) for a disc brake (12) comprising a brake disc (18) and a brake caliper (16) clasping the latter. The brake dust collector (10) includes a housing (24) designed to clasp a portion of the brake disc (18) directly adjoining the brake caliper (16) in the main direction of rotation (R) of the brake disc (18). Provided arranged in the housing (24) is a brake dust retainer comprising a plurality of brake dust intake ports. To ensure practically total retainment of the resulting brake dust without detrimenting, indeed, even improving the cooling of the disc brake (12) the housing (24) features a plurality of air intake ports (34; 38) separate from the inner brake dust intake ports, making it possible to direct the inflow of air in the direction of the brake disc (18) and into the inner brake dust intake ports.
Patent EP-2087245-B1 (EP)
Inventor: SINGH SUMANJIT
IPC: F16B19/10
Filed: 2007-11-28
Granted: 2011-03-02
Abstract: The invention relates to a rivet (2) for connecting workpieces (11, 12), in particular a blind rivet, having a sleeve (1) with a shank (5) and a widened preformed head (13) adjoining thereto, and optionally a rivet mandrel (8) with a head (9), wherein an end of the shank (5) lying opposite the preformed head (13) if necessary can be deformed to form a driven head by drawing the rivet mandrel (8) into the sleeve (1). In order that during the placement of a rivet (2) a gap (10) between the rivet (2) and workpieces (11, 12) to be connected can be closed and a highly loadable connection can be achieved, at least one indentation (3) running axially and/or at least one slot running axially are provided in the shank (5), which indentation (3) or which slot (4) during the placement of the rivet (2) causes a radial expansion of the shank (5) of the sleeve (1) towards the workpieces (11, 12).
Patent EP-1944141-B1 (EP)
Inventor: VOGELBACHER THOMAS
IPC: A47C5/14
Filed: 2008-01-10
Granted: 2012-01-04
Abstract: The method involves gluing the several layers of the seat shell together using pressure and heat. It involves providing at least one of the two outer layers of the seat shell with flocking on the exterior surface prior to gluing to the other layers over at least part of its surface while still flat.
Patent EP-2095999-B1 (EP)
Inventor: HAPPLE WOLFGANG
IPC: B60R13/02
Filed: 2008-02-28
Granted: 2010-04-21
Abstract: Retaining strip has a weakening area (5) in the neighborhood to the direct molded stud (4) with ribs (6) arranged perpendicular to the longitudinal direction of the retaining strip. The ribs are designed as rib-shaped bars formed by slot-shaped recesses (7) that are arranged perpendicular to the longitudinal direction of the retaining strip and parallel to each other.
Patent EP-2159603-B1 (EP)
Inventor: WASLOWSKI KAI
IPC: G01S17/48
Filed: 2008-09-01
Granted: 2011-11-09
Abstract: The object identifying method involves limiting a monitoring area (310,312) on one side by a selected sensing distance (320,322). A light pulse is sent to the monitoring area, where the light pulse reflected on an object, is detected with a row (18) of a photosensitive element (20). The detected signal is integrated by a temporal integration window for the photosensitive element which receives a reflected light pulse, when an object is located in the sensing distance. The temporal integration window comprises two temporal successive sub-integration windows. An independent claim is included for an object identifying sensor for identifying an object in a monitoring area.
Patent EP-2033815-B1 (EP)
Inventor: RIEGER JOHANNES WERNER
IPC: B60C27/08
Filed: 2008-09-01
Granted: 2012-01-25
Abstract: The link assembly has a stud link, which comprises a fastening hole (11), which is bound by a wall and in which a ring member is hinged. Walls (51) of the fastening hole comprise two contact surfaces (52,53) in the contact area with the ring member. The contact surfaces lies at a distance from each other. The ring member is laminarly connected to the contact surfaces with its inner side (54) and between which a removable wall sections (55) lies.
Patent EP-2048234-B1 (EP)
Inventor: VAN URK HENDRIK
IPC: B01D15/38
Filed: 2000-01-31
Granted: 2012-12-19
Abstract: A process is provided for producing recombinant albumin, the process comprising culturing a fungal cell expressing a recombinant albumin coding sequence and obtaining the albumin, wherein the cell has a genetic modification which causes the cell to have at least a reduced capacity of mannosylation of the recombinantly-expressed albumin and wherein the culture medium is at least 1,000L and is of pH 5.3 to 6.8. A process for the preparation of a highly pure albumin solution is disclosed, the process comprising subjecting albumin (preferably expressed and secreted by transformed yeast) to a series of chromatographic steps. A process for reducing the level of nickel in an albumin solution is also disclosed, as is a recombinant albumin coding sequence comprising two or more in-frame translation stop codons.
Patent EP-2050520-B1 (EP)
Inventor: HEINZ RICHARD D
IPC: B21D7/08
Filed: 2008-10-14
Granted: 2011-10-05
Abstract: A cutoff unit (57) for cutting a variably swept continuous beam (56) extending from a roll forming mill (56) includes a pickup subassembly (60) for tracking a shape of the continuous beam (56), and a cutoff subassembly (61) that engages and supports sides of the continuous beam (56) while a blade (64) slices transversely through the continuous beam (56). A controller (55) connected to the roll forming mill (54) and to the cutoff unit (57) controls the cutoff unit (57) to allow pass through of the continuous beam (56), and is configured to actuate the pickup (60) and then actuate the blade (64) to cut the continuous beam (56) into longitudinally symmetrical beam segments (58), each having a center section (51) (swept or not) and with mirror-image equally-swept end sections (52).