baber/WOPTO huggingface dataset:
Patent NZ-270169-A (NZ)
Title: Use of benzothiophene derivatives in the proparation of medicaments for increasing thrombomodulin expression or increasing protein c activation
Inventor: CALNEK DAVID SCOTT
IPC: A61K31/38
Filed: 1994-12-19
Abstract: A method of increasing thrombomodulin expression comprising administering to a human in need of treatment an effective amount of a compound having the formula <CHEM>     wherein R<1> and R<3> are independently hydrogen, -CH3, <CHEM>  wherein Ar is optionally substituted phenyl; R<2> is selected from the group consisting of pyrrolidino, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof. Also encompassed by the invention is a method of inhibiting a thrombotic disorder or event which includes administering to a human in need thereof an effective amount of a compound of formula 1. Also encompassed by the invention is a method of increasing Protein C activation rate which includes the administration of a compound of formula 1.
Patent NZ-272384-A (NZ)
Title: Auger for distributing curtain of powdered or granular food through electrostatic field
Inventor: BURNS ROBERT E
IPC: A23L27/00
Filed: 1995-06-19
Abstract: A dry ingredient distributor is provided which includes an auger surrounded by a distribution tube having a number of openings for discharging granular or powdered material in a curtain along one half of the distribution tube. An electrostatic field generator is mounted to the distribution tube and vertically spaced from it at a preselected distance, and produces a uniform electrostatic field horizontally along the entire length of the distribution tube to generate an electrostatic field in the path of the food material exiting the outlets of the distribution tube.
Patent NZ-274074-A (NZ)
Title: Various dipeptide derivatives having a reduced carboxy group, the aldehyde being optionally substituted; pharmaceutical compositions
Inventor: CORDELL BARBARA L
IPC: C07K5/08
Filed: 1994-09-20
Abstract: This invention relates to compounds and pharmaceutical compositions, and methods for inhibiting or preventing the amyloid protein deposits in the brain which are associated with Alzheimer's disease and aged Down's syndrome patients. More particularly, it relates to the treatment of Alzheimer's disease.
Patent NZ-304052-A (NZ)
Title: Adhesives
Inventor: WEBSTER IAIN
IPC: C09J167/00
Filed: 1996-03-18
Abstract: There are described pressure-sensitive adhesives comprising polyurethanes, polyacrylates, silicones and polyesters which are UV-activated in a solventless system.  There are also described precursors to such pressure-sensitive adhesives, methods of their manufacture and articles comprising pressure-sensitive adhesives.
Patent NZ-329403-A (NZ)
Title: Treatment of B-cell lymphomas using a CD40 binding protein that inhibits the binding of CD40 to CD40L
Inventor: ARMITAGE RICHARD J
IPC: A61K39/395
Filed: 1994-12-21
Abstract: The specification describes a method for treating b-cell lymphomas characterized by neoplastic cells that express CD40.  The method involves administering a therapeutically effective amount of a CD40 binding protein in a pharmaceutically acceptable buffer. CD40 binding proteins include monoclonal antibodies to CD40, and CD40 ligand. CD40 binding proteins may also be used to prevent disease characterized by neoplastic cells that express CD40.
Patent NZ-330908-A (NZ)
Title: Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)piperidin-1-yl)-2 -(aryl)butyl)benzamides useful for the treatment of allergic diseases
Inventor: MAYNARD GEORGE DANIEL
IPC: C07D487/04
Filed: 1997-01-29
Abstract: Provided are substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)b utyl)benzamide derivatives of formula (I).  The compounds are useful as histamine receptor antagonists and tachykinin receptor antagonists. Such antagonists are useful in the treatment of allergic rhinitis, including seasonal rhinitis and sinusitis; inflammatory bowel diseases, including Crohn's disease and ulcerative colitis; asthma; bronchitis; and emesis. Preferred compounds are:  (+)- or (-)-N-Methyl-N-(4-(4-(l-(2-ethoxyethyl)-lH-benzimidazol-2yl-amino)pipe ridin-l-yl)-2-(4-fluorophenyl)butyl)-3,4,5trimethoxybenzamide or a mixture thereof.  (+)- or (-)-N-Methyl-N-( 4-( 4-( l-( 2-ethoxyethyl )-lH-benzimidazol-2- yl-amino)piperidin-l-yl ) -2(3,4- dichlorophenyl)butyl)benzamide or a mixture thereof.  (+)- or (-)-N-Methyl-N-(4-(4-(1-(2-(2,2,2-trifluoroethOxy)ethyl)- lH-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(4- fluorophenyl)butyl)-3,4,5-trimethoxybenzamide or a mixture thereof. (+)- or (-)-N-Methyl-N-( 4-( 4-(l-(4-fluorobenzyl)-lH-benzimidazol-2- yl-amino)piperidin-l-yl)-2-(4-fluorophenyl)butyl)-3,4,5trimethoxybenza mide or a mixture thereof.  (+)- or (-)-N-Methyl-N-(4-(4-(l-(fur-3-yl)-lH-benzimidazol-2-ylamino)piperidin -l-yl)-2-(4-fluorophenyl)butyl)-3,4,5trimethoxybenzamide or a mixture thereof.  (+)- or (-)-N-Methyl-N-(4-(4-(l-(fur-2-yl)-lH-benzimidazol-2-yI- amino)piperidin-l-yl)-2-(4-fluorophenyl)butyl)-3,4,5- trimethoxybenzamide or a mixture thereof.
Patent NZ-332275-A (NZ)
Title: Oven-baked french fries having deep-fried taste and texture
Inventor: KESTER JEFFREY JOHN
IPC: A23L19/12
Filed: 1997-04-16
Abstract: An oven-finished French fried potato product comprises from 32 % to 50 % bulk moisture and from 8 % to 25 % total fat and has a Texture Value of at least 200.  The Texture Value is the maximum force or the area under the force deformation curve during the first one-third of a specific compression test.  The product may be shoestring-cut fries. The product may have a surface water activity of less than or equal to 0.55.
Patent NZ-333312-A (NZ)
Title: Ultraviolet absorbing material comprising an aminosilane and ultraviolet absorbing plate
Inventor: ASANO TUYOSHI
IPC: C08G77/388
Filed: 1997-06-27
Abstract: An ultraviolet absorbing material is prepared by reacting: (a) an aminosilane compound of general formula (1) or a derivative thereof wherein R1 is C1-C10 alkylene or -(CH2)m-NH- (wherein m is an integer of 1 to 4); R2's are each independently hydrogen, hydroxyl, halogeno, C1-C10 alkyl or C1-C10 alkoxy, with the proviso that at least one of R2's is C1-C10 alkoxy; and n is an integer of 0 or above; with (b) an ultraviolet absorber having a carboxyl group in the molecule in such a way as to form an amide linkage resulting from the above aminosilane compound or derivative thereof. This material can form an ultraviolet absorbing layer and applicable to ultraviolet-absorbing glass (ultraviolet absorbing plate), optical devices and light modulators.
Patent NZ-334552-A (NZ)
Title: Device for containing and delivering a payload from a container
Inventor: MURPHY PETER F
IPC: B65D77/24
Filed: 1997-09-03
Abstract: A device for containing and delivering a payload from a container comprises a container, a closure tab which is pivotally connected to a lid and temporarily closes an orifice, and an actuating member which is pivotally secured to lid to actuate the opening of closure tab.  The device includes a capsule disposed within container for containing the payload.  A guide is supported within container and cooperates with the capsule to guide capsule to extend the payload through orifice when closure tab is actuated.
Patent NZ-336307-A (NZ)
Title: Interpolymer composition containing ethylene/alpha olefin interpolymer and cast stretch film therefrom
Inventor: VAN DUN JOZEF J
IPC: C08F210/02
Filed: 1997-11-06
Abstract: An interpolymer composition comprises: a) 10 to 90% by weight of a linear ethylene/a-olefin interpolymer being substituted with 0.01 long chain branches per 1000 carbons to 3 long chain branches per 1000 carbons and b) 10-90% by weight of a heterogeneous ethylene/a-olefin interpolymer having a broad composition distribution present in the composition.  The composition has a i) a viscosity (in poises) satisfying the following relationship:  log(viscosity at 100 rad/s)<4.4.3-0.8 log(I2); ii) a relaxation time (t) satisfying the following relationship:  log(t)>-1.2-1.3 log(I2) or iii) the component a) having two or more distinct ATREF peaks wherein: T2-T1[250C, Mv1/Mv2[1 and Mw/Mn[3 wherein I2 is the melt index of the interpolymer composition as determined in accordance with ASTM D-1238 condition 1900C/2.16Kg; T2 is the ATREF elution temperature of the highest crystallization peak; T1 is the ATREF elution temperature of the lowest crystallization peak; Mv2 is the viscosity average molecular weight at the ATREF peak having the highest elution temperature and Mv1 is the viscosity average molecular weight at the ATREF peak having the lowest elution temperature. The broad composition distribution means that the heterogeneous interpolymer has a linear fraction and has multiple melting peaks.  The heterogeneous interpolymer has a degree of branching of 2 or less methyls/1000 carbons in 10% or more of the interpolymer and a degree of branching of 25 or more methyls/1000 carbons in 25% or less of the interpolymer. A cast stretch film comprising the interpolymer composition as defined above is described.
Patent NZ-336338-A (NZ)
Title: Cryptographic medium containing a plastic base with metallic slivers embedded within, processing means and storage means
Inventor: WACK CARL J
IPC: G06K19/07
Filed: 1997-11-20
Abstract: A cryptographic medium including embedded metallic slivers. The particles provide a unique signature when the card is exposed to a radio frequency signal. The medium includes programming and storage capability, so that protocols for different types of transactions may be stored on the medium, along with personal information associated with the user of the token. The token may take the form of a plastic card, which includes an electronic module fabricated using a multi-chip module design and including the programming and storage capability. The design allows greater computing and storage capacity on the card. At least the electronic module is encapsulated in a plascon material, giving the overall card a more physically secure construction.
Patent NZ-337299-A (NZ)
Title: Game artillery piece, projectile propelled from barrel by foot operated thruster
Inventor: WELLS RONALD GRAEME
IPC: A63B65/12
Filed: 1999-08-17
Abstract: A user lies on the platform 56 gripping the handles 60 and pushes vigorously against a set of pedals positioned alongside the barrel of the cannon.  The strong shove on the pedals forces the plate 26 toward the end of the barrel 16 so that the plastic cannonball 12 is projected out of the end of the barrel.  The pedals are connected to the plate via bolts sliding in the slots 30 on each side of the barrel.
Patent NZ-511047-A (NZ)
Title: Method for treating geothermal fluids by removing contaminants
Inventor: KITZ KEVIN R
IPC: B01D5/00
Filed: 1999-10-22
Abstract: A turbine-condenser system for processing contaminated steam such as mercury, boron or arsenic introduced into the turbine, comprises: (1) a turbine-condenser system; (2) means, located between the final stage of the turbine and the entryway area of the condenser, for collecting moisture formed in the turbine and entrained in the steam prior to the steam being condensed by heat exchange with a coolant fluid; and (3) means for segregating the collected moisture from at least the majority of the steam condensed in the condenser. A steam turbine is surrounded by a shell having means in the exhaust area of the turbine for capturing liquid water produced during expansion of steam in the turbine.  The means is within the shell and located on an internal surface that is exposed to steam passing through the exhaust area. A condenser comprises: (1) a first chamber having an entryway for a vapor to be condensed; (2) means for collecting liquid within the first chamber; (3) a second chamber having an entryway communicating with the first chamber for recovering vapor not condensed in the first chamber; (4) means for condensing vapor in the second chamber by heat exchange across a surface with coolant fluid; (5) means for collecting liquid condensate in the second chamber separate and apart from liquid collected in the first chamber; and (6) means for introducing a coolant fluid, including coolant fluid exiting from surface condensing means into the first chamber to cause condensation of vapor therein by direct contact heat exchange with the coolant fluid.
Patent NZ-513949-A (NZ)
Title: Controlled-release compositions of betahistine
Inventor: FABIANI FLAVIO
IPC: A61K9/26
Filed: 2000-02-28
Abstract: A controlled-release tablet obtained by a) melt granulating betahistine or a pharmaceutically acceptable salt thereof with at least one fatty compound; b) mixing the granulate from step a) with said at least one hydrophilic capable of adsorbing water and with suitable excipients and c) subjecting to compression the mixture from step b).
Patent NZ-517204-A (NZ)
Title: Non-spilling detachable pouring spout
Inventor: VACHON LEANDRE
IPC: B67D7/06
Filed: 2000-08-30
Abstract: An improved pouring spout (1) detachably connected to a filling container (3) for transferring liquid into a receiving container (5).  The pouring spout (1) includes an inlet tube (11) for receiving liquid from the filling container (3), and an outlet tube (21) telescopically mounted to slide onto the inlet tube (11) for guiding liquid therefrom into the receiving container (5).  The spout (1) also comprises a liquid valve (31) which opens and closes automatically upon sliding of the outlet tube (21).  The pouring spout (1) further comprises an air passage (12) and an air valve (51) for regulating an air flow inside the spout (1) from the receiving container (5) into the filling container (3), such that the flow of liquid inside the spout (1) stops automatically when the receiving container (5) is full, thereby avoiding spillage of liquid.  The pouring spout (1) also resolves the problem of emanations related to the transfer of dangerous volatile and highly inflammable liquid.
Patent NZ-519692-A (NZ)
Title: Phenylpiperazinyl, -piperidinyl or -tetrahydropyridinyl derivatives
Inventor: RUHLAND THOMAS
IPC: C07D405/12
Filed: 2000-12-20
Abstract: Described are phenylpiperazinyl, -piperidinyl or -tetrahydropyridinyl compounds of formula (I), wherein: X is N, NR, CR, CHR, O or S, Z and Y are selected from N, C and CR, R is H, alkyl or acyl, U is CR4 or N, V is C, CH or N, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of psychosis, schizophrenia or affective disorders.
Patent NZ-526473-A (NZ)
Title: Pyrazole compounds useful as protein kinase inhibitors
Inventor: BEBBINGTON DAVID
IPC: A61K31/513
Filed: 2001-12-19
Abstract: Pyrazole compounds of formula (IV) are described. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, and for treating diseases such as cancer, diabetes, AlzheimersÆs disease, HuntingtonÆs disease, ParkinsonÆs disease, AIDS-associated dementia, amyotrophic lateral sclerosis, multiple scerosis, schizophrenia, cardiomycete hypertrophy, reperfusion/ischemia and baldness. The compounds are also useful in the manufacture of a medicament for enhancing glycogen synthesis or lowering blood levels of glucose, for inhibiting the production of hyperphosphorylated Tau protein or for inhibiting the phosphorylation of beta-catenin.
Patent NZ-529664-A (NZ)
Title: Method and aqueous composition for the production of improved pulp
Inventor: THOMPSON JACOB OWEN
IPC: D21C3/22
Filed: 2002-06-05
Abstract: Disclosed is an aqueous composition for improving properties of pulp produced, reducing the digester cycle time, or reducing the pulping or bleaching chemicals required in alkaline pulping processes. The composition comprising an alkaline composition of the digester, and at least one compound selected from the compounds of formula (I) to formula (IV), and amine oxides of the phosphonates of formula (I), wherein the compound is in an amount of 0.03% to 1% by dry weight of the wood chips in the digester.
Patent NZ-532123-A (NZ)
Title: Systems and methods for providing digital rights management compatibility
Inventor: CAPITANT PATRICE
IPC: H04N5/00
Filed: 2002-10-17
Abstract: A digital rights management (DRM) system that includes one or more conditional access devices, such as copy control information (CCI) compliant devices, and one or more license (L) compliant devices is described. The L-compliant devices interoperate with the conditional access devices, each L-compliant device and conditional access device sharing a common content access protocol and access information. The system includes an initiator coupled to the L-compliant devices to initialize one or more of the L-compliant devices.
Patent NZ-537203-A (NZ)
Title: Antimicrobial quinolones, their compositions and uses
Inventor: LEDOUSSAL BENOIT
IPC: C07D455/02
Filed: 2003-07-18
Abstract: Disclosed are 3-amino-piperidinyl derivatives of formula (I) wherein the substituents are as described in the specification. The disclosed quinolones are effective antimicrobials, particularly against resistant microbes and provide significant activity advantages including a favourable clastogenecity profile.
Patent NZ-542925-A (NZ)
Title: Use of cilicified microcrystalline cellulose to provide a tablet suitable for oral disintegration
Inventor: PLATTEEUW JOHANNES JAN
IPC: A61K9/00
Filed: 2004-04-16
Abstract: Silicified microcrystalline cellulose is used to provide a tablet with oral disintegration. The tablet contains at least 30% of the silicified microcrystalline cellulose and an effective amount of a pharmaceutically active agent. Particularly disclosed is a non-effervescent tablet for oral administration, comprising an effective amount of an active agent, an amount of at least 30% of silicified microcrystalline cellulose and a disintegrant, such that said tablet is orally disintegratable.
Patent NZ-546784-A (NZ)
Title: Linking transconnector for coupling spinal rods
Inventor: RYAN CHRISTOPHER J
IPC: A61B17/70
Filed: 2004-10-08
Abstract: A linking transconnector (10) is disclosed for coupling a first longitudinal spinal rod to a second longitudinal spinal rod. The linking transconnector generally includes a pair of hook engaging members (50) for engaging the longitudinal spinal rods, a lateral rod (20) for spanning a distance between the hook engaging members, and a locking element (100) which interconnects the hook engaging members with the rod. The locking element is configured to allow for multiple degrees of adjustment to permit the linking transconnector to accommodate for varying spinal rod alignments. The locking elements also permits the location of the lateral rod to be fixed relative to the hook engaging members once the desired position of the lateral rod with respect to the longitudinal spinal rods has been achieved. The locking element may also be able to fix the position of the lateral rod with respect to the hook engaging members by a force applied to the locking element.
Patent NZ-552324-A (NZ)
Title: Methods and reagents for the detection of melanoma
Inventor: WANG YIXIN
IPC: C12Q1/68
Filed: 2005-06-24
Abstract: Provided is a method of identifying a melanoma comprising the step of a. measuring the expression levels in a tissue sample of genes encoding mRNA corresponding to specified sequences of PLAB and L1CAM or PLAB, L1CAM and NTRK3, wherein the gene expression levels above pre-determined cut-off levels are indicative of the presence of a melanoma in the sample, and wherein the pre-determined cut-off levels are at least two-fold over-expression in tissue having metastatic melanoma relative to benign melanocyte or normal tissue.
Patent NZ-553989-A (NZ)
Title: Immunogenic bacterial vesicles with outer membrane proteins
Inventor: ADU-BOBIE JEANNETTE
IPC: C12N9/10
Filed: 2005-10-28
Abstract: Provided is an isolated Neisseria meningitidis bacterium, wherein: (i) the bacterium has a cell wall that includes peptidoglycan; and (ii) the bacterium does not express a protein having the lytic transglycosylase activity of MltA protein; (iii) the bacterium has a knockout of its mltA gene; and (iv) the bacterium has a knockout mutation of at least one further gene. Further provided are vesicles produced by the said bacterium and use of the bacterium for the manufacture of medicaments for inducing immune responses.
Patent NZ-569654-A (NZ)
Title: Device for filling of a container of collapsible type
Inventor: GUSTAFSSON PER
IPC: B65B39/10
Filed: 2007-02-01
Abstract: A device for filling a container (2) of a collapsible type with a liquid product is provided. The container (2) has a compartment which is defined by flexible walls and whose volume is dependent on the relative position of the walls and which communicates with the surroundings via a filling duct (3) of the container (2). The container includes a filling tube (4) with an end portion (6), which is insertable into the filling duct (3) of the container (2) for supplying a product to the compartment of the container (2) through the filling tube (4). The device includes a clamping means (5), which is adapted to grasp the end portion (6) and the filling duct (3) when the end portion (6) is inserted into the filling duct (3) to provide a seal between the end portion (6) and the filling duct (3). The clamping means (5) has gripping surfaces (9) which are arranged to cooperate with the circumferential surface of the end portion (6) in the state of the clamping means (5) grasping the filling duct (3) and the end portion (6) to provide the seal between the end portion (6) and the filling duct (3). Each gripping surface (9) has opposite edge portions, with a bead arranged in each edge portion. The end portion (6) has a circumferential surface which is formed of two opposite partial surfaces which each comprise a convexly curved central portion and a concavely curved side portion arranged on each side of the central portion. The partial surfaces are arranged with the convexly curved central portions facing away from each other. The side portions of the opposite partial surfaces on the respective sides of the central portions connect to each other in a converging manner, and each concavely curved side portion forms a recess in the neighbouring concavely curved central portion.
Patent NZ-570103-A (NZ)
Title: Compounds and methods for modulating protein trafficking
Inventor: BULAWA CHRISTINE
IPC: A61P3/10
Filed: 2007-01-26
Abstract: Disclosed the use of imine compounds represented by general formula (I), wherein X is O, S or NR and Y is NRR' or OH and the other substituents are disclosed within the specification, for treating cystic fibrosis.
Patent NZ-571142-A (NZ)
Title: Synthesis of acylaminoalkenylene amides such as (4R)-4-[N'-methyl-N'-(3,5-bistrifluoromethyl-benzoyl)-amino]-4(-3,4-dichlorobenzyl)-but-2-enoic acid N-[(R)-epsilon-caprolactam-3-yl]-amide hemihydrate useful as substance P antagonists
Inventor: PORTMANN ROBERT
IPC: A61K31/55
Filed: 2007-04-11
Abstract: Disclosed is a process for preparing compounds of formula I, or a solvate or hydrate thereof, where R is phenyl; R1 is hydrogen or C1-C7-alkyl; R2 is hydrogen, C1-C7-alkyl or phenyl; R3 is phenyl, naphthyl, 1H-indol-3-yl or 1-C1-C7-alkyl-indol-3-yl; and R5 is C3-C8-cycloalkyl, D-azacycloheptan-2-on-3-yl or L-azacycloheptan-2-on-3-yl, and the substituents can be substituted as defined in the specification. The compounds produced by the process are useful in the treatment of conditions associated with substance P and neurokinin.
Patent NZ-572460-A (NZ)
Title: A cable suspension device with cable slidable through securing means under mechanical overload
Inventor: EFRAIMSSON LARS
IPC: H02G7/04
Filed: 2006-04-28
Abstract: The present disclosure relates to problems how to keep cable arrangement functional, or at least make the damage as little as possible, after being exposed to different types of mechanical overloads . The problems are solved by methods and arrangements in which the securing means and the contact material of the securing means are arranged so that the cable can slide through the securing means when it is exposed to mechanical overloads .