baber/WOPTO huggingface dataset:
Patent CA-2471346-A1 (CA)
Inventor: JAMES PETER
IPC: G01N27/62
Filed: 2002-12-16
Abstract: The present invention is a method for analysis of at least peptides comprising extracting proteins from at least one set of cells; digesting the extracted proteins; derivatising the protein fragment mixture with an isotopically labelled reagent molecule; separating the protein fragment mixture by multi-dimensional chromatography; and analysing the protein fragment mixture by mass spectroscopy (MS) in parent ion or neutral loss scanning mode, thereby detecting or measuring the amounts of the labelled protein fragments. In a preferred embodiment, two sets of cells are combined in the method in order to compare the expression levels of two different states. Moreover, the invention relates to a kit for use in the present labelling method.
Patent CA-2471630-A1 (CA)
Title: Process for producing snack, snack and snack-like food
Inventor: HIROTO SAKIKO
IPC: A23L1/164
Filed: 2002-10-24
Abstract: A production method for snack cake which can produce cake providing a potato chip-like mouth feeling and using bread as a raw material. A piece of bread (1) having its brown-baked crust removed and sliced to at least 1 mm in thickness is pressurized and heated by a press device (2). When the water content of the bread (1) reaches almost 30 mass%, the bread (1) is removed from the press device (2) and is dried by hot air to about 5 mass%, whereby a processed food (snack cake before seasoned) having the outer edge portions thereof curled is obtained.
Patent CA-2472256-A1 (CA)
Title: Femoral head assembly with variable offset
Inventor: BURKINSHAW BRIAN
IPC: A61F2/30
Filed: 2004-06-25
Abstract: A proximal femoral head assembly having a variable offset that is selectively adjustable to conform to various anatomical conditions encountered during a femoral surgical procedure. The assembly includes a femoral head, a neck removeably connectable to the femoral head, and an adjustment mechanism.  The adjustment mechanism provides the neck with a plurality of different femoral offsets with respect to a femoral hip stem.
Patent CA-2472931-A1 (CA)
Title: Cup holder
Inventor: DARZINSKAS RAYMOND
IPC: B65D25/36
Filed: 2004-07-02
Abstract: A holder for a cup comprising a foamed plastic pliable sleeve having an open top and bottom for receiving said cup.
Patent CA-2473364-A1 (CA)
Title: Strand orientation alignment in strand coating systems and methods
Inventor: VALENTIN RICO R
IPC: B05C5/02
Filed: 2004-07-09
Abstract: A strand coating system and method including drawing (710) a strand having major and minor dimensions past an adhesive dispensing nozzle, orienting (720) at least a portion of the strand so that the major dimension of the strand is substantially parallel to a direction in which adhesive is dispensed from the adhesive dispensing nozzle as the portion of the strand is drawn past the adhesive dispensing nozzle, and applying (730) adhesive to the strand as the strand is drawn past the adhesive dispensing nozzle.
Patent CA-2477462-A1 (CA)
Title: Container, especially reusable container, comprising collapsible lateral walls
Inventor: BARTH CHRISTIAN
IPC: B65D/
Filed: 2003-02-28
Abstract: In a container, especially a returnable container, equipped with collapsible side walls the snap interlock in the corner region is in each case constituted by a pressure lever that can be pressed inwards and interacts with a locking catch situated on the side wall adjacent at the given edge.
Patent CA-2479875-A1 (CA)
Inventor: HANNING-LEE MARK A
IPC: H03M1/18
Filed: 2003-03-18
Abstract: A high speed analog to digital converter ("ADC") (12) that can be used in a detector system (10). The ADC is coupled to a detector (14) and a processor (18). The detector (14) generates an analog signal in response to the detection of a trace sample, such as an ionized molecule or a beam of light.  The processor (18) determines a baseline value and threshold value. Portions of the analog signal at or below the threshold are assigned the baseline value. The threshold typically corresponds to a value above the noise level in the system. The detector (14) thus removes undesirable noise from the readout value. The process can compensate for factors such as DC drift while providing accurate data regarding detection of the trace sample.
Patent CA-2480248-A1 (CA)
Title: Medical imaging apparatus
Inventor: ROBERTSON DUNCAN ALEXANDER
IPC: A61B5/01
Filed: 2003-03-26
Abstract: A medical imaging apparatus for imaging subcutaneous body temperature that comprises a detector (22) for sensing millimetre wave electromagnetic radiation and a collector for collecting radiation emitted from a patient's body and directing it along a collection path (20) to the detector. The collector is configured so that the collected radiation has a defined sensitivity profile across and along substantially the entire length of that path. The collected radiation may have a Gaussian or a Bessel sensitivity profile.
Patent CA-2482344-A1 (CA)
Title: Blanking station of a diecutting press
Inventor: JAQUET BERNARD
IPC: B26D7/06
Filed: 2004-09-22
Abstract: This blanking station of a diecutting press comprises an upper cradle (2) for a blanking device and gripper bars (23) for conveying the sheets in progress (4). This upper cradle comprises means (2a, 2b) for the removable mounting, alternately to a blanking device and to a delivery device (1) of non- severed sheets. This station further comprises at least one cam (24) for opening the grippers (23a) of the said gripper bars (23), mounted in removable manner.
Patent CA-2483046-A1 (CA)
Title: Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
Inventor: GOODRICH RAYMOND P
IPC: A61K35/14
Filed: 2003-05-06
Abstract: This invention provides methods for treating cellular blood components and other cells containing mitochondria to improve vital qualities of the cells by contacting the cells with a mitochondrial enhancer to the cells. Mitochondrial enhancers prevent damage to and rejuvenate mitochondria and cells containing mitochondria. Mitochondrial enhancers include alloxazines and related compounds, such as riboflavin. Cells are optionally treated with photoradiation to reduce pathogens with may be present, before, after, and/or during treatment with mitochondrial enhancer. Treating with mitochondrial enhancer enables utilization of higher photoradiation energies, which achieves better pathogen reduction. When platelets are treated with mitochondrial enhancer, treated platelets may be stored for longer times than untreated platelets before they are administered to patients.
Patent CA-2484554-A1 (CA)
Title: Diagnostic test for determining the concentration of transient proteolytic activity in composite biological media
Inventor: WAGENVOORD ROBERT
IPC: G01R33/465
Filed: 2003-05-01
Abstract: A method is provided for determining in real time the course of thrombin activity in a sample of blood or plasma as it appears in and disappears from the sample which comprises adding a thrombin substrate to the sample that, per unit time, produces a detectable signal in a quantity that bears relation to the amount of thrombin present. Simultaneously, in a control sample of the same blood or plasma in which thrombin generation is not triggered, the activity of a standard preparation with invariable thrombin activity is measured. The exact molar amount of thrombin present at any moment is obtained by comparison of the activity measured in clotting blood and the simultaneously measured calibrator. The method is useful inter alia for diagnosing hyper- and hypo-coaguable states, either congenital, acquired or drug-induced in humans and animals. Also provided is a kit for use in this method.
Patent CA-2485445-A1 (CA)
Title: Toothbrush head
Inventor: MANGAN EDWARD J
IPC: A46B7/06
Filed: 2004-03-09
Abstract: A toothbrush comprising a head having one or more tooth cleaning elements extending from the head. The head is divided into at least two portions which can be moved independent of each other. The toothbrush also comprises an electric motor having an output shaft, which when rotated causes vibration.
Patent CA-2487407-A1 (CA)
Title: Lever-actuated high-pressure gas tap adjustable to different bottlenecks
Inventor: PISOT PHILIPPE
IPC: F16K31/524
Filed: 2003-05-15
Abstract: The invention relates to a tap controlling the dispensing of a pressurized fluid, particularly a gas, comprising a valve body (1) that has an axis (XX) and is provided with an internal passage (10) for the fluid, which extends from an inlet port (8) to an outlet port (9), a fastening base (12) which has an axis (XX), coaxially supports the inlet port (8) of the internal passage (10), and the outer periphery of which is threaded, an outlet connection (4) which has an axis (BB) and supports the outlet port (9) of the internal passage (10), a manometer (5) which has an axis (AA) and the pressure-metering means of which is connected to the internal passage (10), an engaging member (11) which is disposed between the manometer (5) and the fastening base (12), and a lever (2) which pivots around an axis (YY) that runs perpendicular to the axis (XX) and cooperates with at least one valve (33) that acts upon the internal passage (10) such that the fluid can circulate or is prevented from circulating from the inlet port (8) to the outlet port (9) of the internal passage (10). The inventive tap is characterized by the fact that the height (H1) between the base of the engaging member (11) and the axis (BB) of the connection (4) ranges between 60 and 75 mm while the height (H3) between the base of the engaging member (11) and the axis (YY) of the lever (2) ranges between 50 and 110 mm. Also disclosed is a gas container comprising such a tap.
Patent CA-2487505-A1 (CA)
Title: Sliding axle alarm
Inventor: TRUDEAU CURTIS A
IPC: G08B3/06
Filed: 2004-11-09
Abstract: An alarm system that indicates to an operator the status of locking pins of a vehicle sliding axle assembly. The alarm system includes an alarm valve coupled to the locking pins and in fluid communication with an alarm. When the pins are unlocked from a vehicle component, the alarm valve is configured in an alarm mode to indicate the unsecured condition of the assembly. In this mode, air is diverted from the vehicle brakes to sound the alarm, thereby informing an operator that the pins are improperly engaged. In one embodiment, the alarm valve is in communication with or includes a pressure relief valve, which diverts a sufficient amount of air from the vehicle brakes so that the brakes cannot be released. When the pins are properly locked to secure the slider axle assembly, the alarm valve does not divert air from the brakes to sound the alarm.
Patent CA-2488003-A1 (CA)
Title: Method for dynamic representation of processes and computer program product implementing same
Inventor: LANG ROBERT
IPC: G06Q10/06
Filed: 2003-05-30
Abstract: A computer-based method for representing a project includes accessing a description of the project, generating a graphic display of at least a porti on of the project based on the description, and dynamically updating the graphi c display in response to a s change in the description of the project. A computer program product for representing a project includes instructions th at cause a processor to convert a description of the project into display instructions for displaying relative progress of the project relative to, bu t independently of, an expectation of progress and displaying a relative rate of progress of the project relative to, but independently of, an expectation of a rate of progress. The 10 computer program product is tangibly stored on machine readable media.
Patent CA-2489521-A1 (CA)
Title: Device for applying controlled and adjustable compression on a limb
Inventor: COUNORD JEAN-LOUIS
IPC: A61B17/00
Filed: 2003-06-18
Abstract: A tubular sleeve ( 40 ) comprises an anterior portion ( 16 ) of inextensible material that comes to bear against the tibial ridge, and a posterior portion ( 18 ) of extensible material covering the region to be compressed. These two portions are connected together along two connection generator lines ( 20 ). Inflatable balloons ( 22 ) are disposed on the inside face of the anterior portion, being interposed between the inextensible material and the tibial crest. Means ( 24, 26, 28 ) are provided for inflating each of the balloons differently to a respective given pressure so as to apply deformation to the anterior portion of the sleeve that is suitable for inducing a traction force that is exerted on the extensible posterior portion; this force is distributed regularly along the generator lines and acts perpendicularly thereto, and consequently leads to compression action on the compressible region of the limb.
Patent CA-2494386-A1 (CA)
Inventor: JOHNSTON RENEE
IPC: H04Q1/457
Filed: 2005-01-26
Abstract: The present invention relates generally to tone detection in echo canceling systems, and more particularly to a method of monitoring oscillations of adaptive filter coefficients for narrow band tone detection in echo cancellation systems. The invention is directed at improving communication in a telephone communication network having one or more hybrid connections. A method for detecting continuous tones in an echo canceling system having an adaptive filter is provided. Continuous tones have a deleterious effect on the performance of adaptive filters. In the present invention, the adaptive filt er coefficients are monitored. Oscillation of those coefficients indicates continuous tone presence.
Patent CA-2494594-A1 (CA)
Title: Article chaussant impermeable a l'eau et ventile
Inventor: GRANDINI GABRIELE
IPC: A43B17/08
Filed: 2003-03-04
Abstract: L'invention concerne un article chaussant qui comprend en combinaison : une semelle extérieure (11) comportant dans sa partie antérieure au moins une ouverture (12) d'aération formée à travers l'épaisseur de la semelle (11) ; un élément (13) du type grille placé dans cette ouverture (12) et servant d'écran, pour séparer et protéger l'intérieur de la chaussure du sol en contact avec la semelle (11) ; une feuille d'insertion (15) pliable faite d'une matière respirante et imperméable à l'eau, qui est incorporée dans la semelle (11) et positionnée à l'intérieur de celle-ci (11) de manière à recouvrir l'ouverture (12) ; une semelle intérieure (16) faite d'une matière respirante et imperméable à l'eau ; et une tige (17) faite d'une matière respirante et imperméable à l'eau.
Patent CA-2496515-A1 (CA)
Inventor: UDY DAVID B
IPC: B25H3/04
Filed: 2003-08-26
Abstract: A storage device (10) for compactly storing elongate tools (66) includes a plurality of receptacles (12) arranged in a support in at least front and rear substantially linear rows (16, 18). Each receptacle includes at least a lower receiving port (20) and an upper receiving aperture (22) in which a tool can be held when disposed through the upper receiving aperture and into the lower receiving port. The receptacles of the front row are forwardly splayed at a forward angle (b2) with respect to vertical (23) greater than the receptacles of the rear row. The receptacles within each row are laterally splayed with respect to vertical, with receptacles within each row being oriented at progressively increasing lateral angles (al, b l) with respect to vertical from receptacles at a center to receptacles at lateral ends of each row.
Patent CA-2499903-A1 (CA)
Title: Derives 1,4-di-piperidin-4-yl-piperazines substitues en 1,4 et leur utilisation en tant qu'antagonistes des neurokinines
Inventor: LEENAERTS JOSEPH ELISABETH
IPC: C07D471/04
Filed: 2003-10-07
Abstract: L'invention concerne des dérivés di-pipéridin-4-yl-pipérazines substitués en 1,4 possédant une activité antagoniste des neurokinines, notamment une activité antagoniste de NK¿1?, leur préparation, des compositions les contenant et leur utilisation en médecine, notamment pour le traitement du vomissement, de l'anxiété, de la douleur, de la pancréatite et du syndrome du côlon irritable. Les composés de l'invention peuvent être représentés par la formule générale (I), et comprennent également les sels d'addition d'acide ou de base de ceux-ci, des formes isomères stéréochimiquement de ceux-ci, la forme <I>N</I>-oxyde de ceux-ci et des promédicaments de ceux-ci, tous les substituants étant tels que définis dans la revendication 1. Compte tenu de leur capacité à avoir un effet antagoniste aux neurokinines en bloquant les récepteurs des neurokinines, et notamment aux actions de la substance P en bloquant le récepteur NK¿1?, les composés de l'invention sont utiles en tant que médicaments, en particulier dans le traitement prophylactique et thérapeutique d'états médiés par les neurokinines, tels que, par exemple, les troubles du SNC, notamment la dépression, les troubles de l'anxiété, les troubles liés au stress, les troubles du sommeil, les troubles cognitifs, les troubles de la personnalité, les troubles schizo-affectifs, les troubles alimentaires, les maladies neurodégénératives, les troubles addictifs, les troubles de l'humeur, la dysfonction sexuelle, la douleur et d'autres états liés au SNC ; l'inflammation ; les troubles allergiques ; le vomissement ; les troubles gastro-intestinaux, notamment le syndrome du côlon irritable ; les affections cutanées ; les maladies angiospastiques ; les maladies du collagène et fibrosantes ; les troubles relatifs à l'augmentation ou la réduction de l'immunité, les maladies rhumatismales et la régulation du poids.
Patent CA-2501924-A1 (CA)
Title: Non-nucleoside reverse transcriptase inhibitors
Inventor: SUND CHRISTIAN
IPC: C07D409/12
Filed: 2003-09-05
Abstract: A compound of the formula (Y): where; R1 is O, S; R2 is a nitrogen-containin g heterocycle; R3 is H, Cl-C3 alkyl; X is -(CR8R8')n-D-(CR8R8')m-; D is a bond , - NR9-, -O-, -S-, -S(=O)- or -S(=O)2-; n and m are independently 0, 1 or 2, R8 and R8' are independently H, C1-C3 alkyl, haloC1-C3alkyl, hydroxy, or R8 and R8' together with their adjacent C atom is -C(=O)-; R9 is independently H, C 1- C3 alkyl; E is CH2-, -CHOH-, -C(=O)-, -NR9-, -O-, -S-, -S(=O)2-; n and m are independently 0, 1 or 2; p and q are independently 0, 1 or 2, where p+q < = 2; R10 is an optionally substituted carbocycle or heterocycle; R11 is independently H, C1-C3 alkyl, halo substituted Cl-C3alkyl, hydroxy; have utility as HIV antivirals.
Patent CA-2503312-A1 (CA)
Title: Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
Inventor: AOUTHMANY MOUSTAFA M
IPC: C07C229/60
Filed: 2003-11-17
Abstract: A method and compositions for treating persistent pulmonary hypertension in human newborns that deploys an intravenous infusion of a modified drug formed by adding one or more of a predetermined chemical arrangement to an efficacious parent drug compound so as to retain efficacy while re-directing a preferred route and rate of the parent drug compound's metabolism to an inactive or very weakly active and non-toxic metabolite are disclosed. The chemical arrangement is ~-R-X-R'; wherein ~ is a phenyl, substituted aryl or heteroaryl system that is already present in the parent drug compound or is specifically added to the parent drug compound via a metabolically stable connection; R is an alkyl or alkene containing chain either branched or unbranched from 0 to 10 carbons that is already present in the parent drug compound or is added to the parent drug compound via a metabolically stable connection to ~; X is a carboxyl, sulfoxyl or phosphatyl function that is specifically added to the parent drug compound via a metabolically stable connection to R; and, R' is an added alkyl, alkenyl or aralkyl group either branched or 20 unbranched containing from 1 to 10 carbons, or is a structural element already present as an inherent portion of the parent drug compound.
Patent CA-2505504-A1 (CA)
Title: Breathing assistance apparatus
Inventor: WIXEY DAVID FRASER
IPC: A61M16/00
Filed: 2003-10-29
Abstract: The present invention may include an integral, separable or separate humidifier (100) which may be selectively configured to an inoperative or operative state. The switch over is dependent on the user or the seller havi ng access to an actuation tool to activate the humidifier. The Continuous Positive Airway Pressure (CPAP) device is initially available for use as a standalone CPAP (100). The heater plate being isolated by a covering shroud (102), the shroud (102) also forms a connection port for the CPAP blower outlet (104). The heated humidification hardware being disabled by the absen ce of the activation tool. Upgrade to a CPAP device including heated humidification is completed by the installation of the actuation tool. Remov al of the heater plate isolating shroud and/or installing the actuation tool enables the software controlled heated humidification hardware for heated humidifier operation. Other upgrades to functionality are also disclosed.</S DOAB>
Patent CA-2509121-A1 (CA)
Inventor: ALBIZURI LANDA INIGO
IPC: F16K5/02
Filed: 2005-06-03
Abstract: The cooking appliance (1) having a control panel (2) is equipped with one or more gas flow (Q) regulating valves, wherein the rotary regulator organ (6) is provided with various peripheral through holes (16-19). The control knob (9) being interchangeable for fitting to the actuating shaft (7), is chosen from the two units available, one and the other permitting different angular limit positions (A2, A3) for the supply of a constant minimum gas flow Qmin, through one of two successive holes (18, 19) calibrated each one for a different type of gas NG or LPG, one or the other hole being superimposed to a valve inlet duct (4) at a different angular position A2, A3. An integral lug (14) on the control knob (9) running into a slide groove (20) in the control panel (2), establishes a first rotation stop A2.
Patent CA-2509607-A1 (CA)
Title: Cytochrome c acetylation
Inventor: SOLOMON JONATHAN M
IPC: C12N9/80
Filed: 2003-12-15
Abstract: Modulation of cytochrome c acetylation, e.g., with a SIR polypeptide, enables interventions that modulate lifespan regulation and cell proliferation, e.g., by modulating apoptosis and/or mitochondrial function such as respiration.
Patent CA-2511816-A1 (CA)
Inventor: NEUMAN TOOMAS
IPC: C12Q1/68
Filed: 2003-12-24
Abstract: L'invention concerne des compositions et des méthodes permettant de diagnostiquer le cancer, de déterminer un pronostic pour le cancer, et d'identifier des sous-types de cancers pour une variété de cancers. L'invention concerne également des compositions et des méthodes de traitement du cancer.
Patent CA-2512827-A1 (CA)
Inventor: JENKINS DENNIS
IPC: A61F9/00
Filed: 2005-07-21
Abstract: An eye shield attachment can be used in combination with a safety helmet. The helmet has a front brim continuous with a rim extending along each opposite side of the safety helmet adjacent to a pair of rim slots in the rim of the safety helmet. The eye shield attachment has a lens and a right and a left structure. Each of the right and left structures has (a) a side frame adapted to be suspended below the rim and to extend toward the front brim, and (b) at least one tong adapted to be removably and dependently attached from below to a corresponding one of the rim slots in the helmet for supporting the side frame. The lens is attached distally between the right and the left structures and can pivot under the front brim between a lowered and a raised position and still remain subjacent to the front brim. The right and left structures are adjustable to provide an adjustable orientation of the lens while in the lowered position.