baber/WOPTO huggingface dataset:
Patent NZ-548619-A (NZ)
Title: Anthranilic acid derivatives, their preparation and use as inhibitors of dihydroorotate dehydrogenase
Inventor: JONSSON STIG
IPC: A61K31/195
Filed: 2005-02-04
Abstract: Anthranilic acid derivatives of formula (I), which are potent inhibitors of dihydroorotate dehydrogenase (DHODH), to be used for clinical treatment of autoimmune diseases, inflammatory diseases, organ transplant rejection and malignant neoplasia are disclosed. Also disclosed is a pharmaceutical composition comprising a compound of formula (I) in an amount giving a daily dosage of from 0.005 mg/kg to 10 mg/kg body weight, in particular from 0.025 mg/kg to 2 mg/kg body weight. These compounds and pharmaceutical compositions are particularly useful for preventing and treating acute and chronic inflammation, rheumatoid arthritis, multiple sclerosis, type-l diabetes, inflammatory bowel disease, psoriasis, transplant rejection and malignant neoplastic disease.
Patent NZ-549803-A (NZ)
Title: Method and system for centering a workpiece on the central axis of a cylindrical bore
Inventor: WISEMAN ROBERT B
IPC: G01D21/00
Filed: 2005-04-01
Abstract: A method for centering a work piece on the central axis of a cylindrical bore 100 in a body, the work piece including a rod, the method comprising: (a) inserting into an end of the bore 100 an arbor 300 having a cylindrical exterior surface matingly slidable within the cylindrical bore 100, the arbor 300 having a symmetrical reference pin protruding from an end of the arbor 300 coaxially with the central axis; (b) sensing the position of the reference pin in a plane transverse to the central axis and transmitting pin position data to a computer system 400; (c) computing a center of the reference pin from the pin position data and representing the reference pin center as a bore 100 axis target; (d) removing the arbor 300 from the bore 100 and inserting the work piece into the bore 100 with the rod protruding from the end of the bore 100; (e) sensing the position of the rod in the plane traverse to the central axis and transmitting rod position data to the computer system 400; (f) computing a center of the rod from the rod position data and representing the rod center as a rod target; and (g) adjusting the position of the rod to bring the rod target substantially coincident with the bore 100 axis target.
Patent NZ-555463-A (NZ)
Title: Unidirectional translation system for bone fixation with interengaging teeth for resilient engagement
Inventor: BARRALL BENJAMIN S
IPC: A61B17/70
Filed: 2005-11-30
Abstract: A fixation assembly (100) is described comprising at least two plates (10, 60), one of which may be a contoured plate (10) and one of which may be a securing plate (60). The contoured plate may have a plurality of teeth (50b, 52b), and the securing plate may have a resilient securing element (74). The teeth may be arranged so that the resilient securing element encounters progressive resistance as the plates are compressed by having the teeth in plural rows of increasing distance in a transverse extent.
Patent NZ-555948-A (NZ)
Title: Systems, methods, software, and interfaces for multilingual information retrieval
Inventor: MOULINIER ISABELLE
IPC: G06F17/30
Filed: 2006-01-04
Abstract: A system for multilingual information retrieval comprises a collection of documents; a set of one or more language-specific indices for the collection of documents and a server for interacting with the collection of documents and the set of language-specific indices. Each index includes stemmed and non-stemmed versions of terms contained in the documents. The server receives a query from a user. The query is associated with a set of one or more target languages. The server parses the query into one or more terms. Each term is associated with a corresponding language identifier and a stemmed version of the term. The server translates the original and stemmed versions of each term of the query into each of the target languages defining respective sets of one or more equivalent query terms. The server identifies a set of documents from the collection of documents for each of the target languages, with each set identified based on the equivalent query terms for the corresponding target language.
Patent NZ-560519-A (NZ)
Title: Lens delivery system
Inventor: TRAN SON TRUNG
Filed: 2007-08-10
Abstract: An intraocular lens delivery system is disclosed. The intraocular lens delivery system comprises a body, where the body has a first platform and a second platform, and the platforms are sized and shaped to receive components of a multi-component intraocular lens. Also includes is a first lid and a second lid for covering the first platform and the second platform, respectively, a nozzle on the distal end of the body, where the nozzle has a removable lid, a ring pusher associated with the first platform and adapted for reciprocal movement within the first platform, a plunger associated with the second open platform, and a removable shipping lock for preventing movement of the ring pusher.
Patent NZ-563335-A (NZ)
Title: An animal medication delivery device and a method for its use
Inventor: LEECH WAYNE FREDERICK
IPC: A61D7/00
Filed: 2007-11-26
Abstract: A delivery device for delivering a solid treatment into an orifice of an animal is disclosed. The delivery device 1 comprises a chamber 6 for the solid treatment, an outlet 7 for the solid treatment, and a displacement means 8 for the solid treatment. An actuator 4 activates the delivery force to be applied to the solid treatment via the displacement means which causes the solid treatment to exit the chamber through the outlet. A rearming mechanism is configured to apply a rearming force to the displacement member. A delivery force is configured such that that the rearming force applied to the rearming mechanism is separate to and greater than the delivery force.
Patent NZ-563849-A (NZ)
Title: One-piece container with a hollow needle able to be emptied in one stroke from thumb pressure
Inventor: WEIBEL-FURER LUDWIG
IPC: B67D7/74
Filed: 2006-05-18
Abstract: Disclosed is a container (1), for the housing and dispensing of a medicament, the container exhibits a volume of less than 5 ml. The container comprises a one-piece collapsible-tube-shaped case (6) which is sealed except an opening (4) for dispensing the medicament. The container is designed so that alteration of one region of the casing causes the release of the medicament. The container exhibits a hollow needle in the region of the opening, with the hollow needle being formed integrally with the opening. The casing of the container is at least partially elastic and the container is designed so it can be emptied in one stroke by pressure with the thumb.
Patent NZ-575655-A (NZ)
Title: Nutrient sensor
Inventor: ROE CHARLES R
IPC: A61K31/225
Filed: 2007-09-26
Abstract: Disclosed is the use of Fatty acids for the treatment of Catchexia by treating the effects of catabolism in a patient by providing the patient with an amount of an odd-chain fatty acid sufficient to increase the intracellular ratio of AMP to ATP and reduce the activity of AMPK.
Patent NZ-576693-A (NZ)
Title: Method of radio-sensitizing tumors using 4-methoxy-carbazoles compounds
Inventor: DIEBOLD JAMES L
IPC: A61K31/00
Filed: 2007-11-20
Abstract: A dosage regime formulated for application in the treatment of cancer in a mammal the regime comprising: (a) a radiosensitizing agent of formula (I); or a pharmaceutically acceptable salt form thereof, wherein, wherein the substituents are as defined in the specification (preferably the radiosensitizing agent is 7-methoxy-1,2,3,11-tetrahydro-5,11-diazabenzo[a]trindene-4,6-dione or 7-methoxy-5-(4-methyl-piperazin-1-ylmethyl)-1,2,3,11- tetrahydro-5,11-diaza-benzo[a]trindene-4,6-dione); and which is formulated for administration to cancer cells; and(b) a dosage of ionizing radiation which is formulated for administration to said mammal to irradiate mammalian tissue, preferably cancer cells.
Patent NZ-577660-A (NZ)
Title: Pressure limiting valve with dual back to back valve elements
Inventor: CRICHTON DAVID GORDON ARTHUR
IPC: E03B7/09
Filed: 2009-06-15
Abstract: A liquid pressure limiting valve has a unitary body 1c incorporating a liquid passage therethrough joining an inlet port 3 with an out port 4. The passage has a volumetric capacity commensurate to the volumetric capacity of a pipe in which the valve is intended to be "in-line" mounted. Mounted within the body 1c are two pressure limiting mechanisms 8 each including an opening and closing displacement element 17 operational in conjunction with an associated outlet aperture defined by valve seat 14. The outlet apertures and their associated valve mechanisms 8 form part of the liquid passage through the valve and in so doing they are arranged in parallel with one another. Each valve mechanism 8 has a volumetric capacity commensurate to one half of that of the inlet and outlet ports 3 and 4.
Patent NZ-579207-A (NZ)
Title: System and method for preparing a liquid beverage from a cartridge to reduce high pressure discharge from the cartirdige when pierced
Inventor: DENISART JEAN-LUC
IPC: A47J31/06
Filed: 2008-02-27
Abstract: Disclosed is a liquid drink brewing system to reduce the risk of high pressure hot liquid discharging from the capsule. The system for preparing a liquid beverage from a cartridge comprises the preparation machine containing a supply unit for supplying injection fluid or water to the cartridge. Also the machine contains a cartridge support to securely hold a cartridge and injection means that are able to move relative to the cartridge holder in order to inject an injection fluid into the cartridge. The cartridge comprises an injection surface; and is positioned in the supply unit in an injection position so that the injection surface of the cartridge is held in a plane inclined at less than 45 degrees relative to the horizontal plane. The injection means are offset from the highest side of the cartridge after engagement of the injection means against the injection surface of the cartridge.
Patent NZ-582490-A (NZ)
Title: 8-beta-substituted estratrienes as selectively active estrogens
Inventor: PETERS OLAF
IPC: C07J1/00
Filed: 2008-07-11
Abstract: The disclosure relates to 8beta-substituted estra-1,3,5(10)-triene derivatives of general formula (I), wherein the variables are as defined in the specification, their use as pharmaceutical active ingredients, which have in vitro a higher affinity to estrogen receptor preparations from rat prostates than to estrogen receptor preparations from rat uteri and in vivo a preferential action in the ovary in comparison to the uterus, their production, their therapeutic use and pharmaceutical dispensing forms that contain these compounds. These compounds are suitable for the treatment of estrogen-deficiency-induced diseases and conditions, such as peri- and postmenopausal symptoms, female infertility; for therapy of hormone-deficiency-induced symptoms in ovarian dysfunction;, for prophylaxis and therapy of inflammatory intestinal diseases, Crohn' s disease, inflammatory diseases of the skin, psoriasis, cardiovascular diseases, prostate- hyperplasia, prostate hyperplasia, diseases of the immune system, endometriosis; for the treatment of cancer of the colon and small intestine; and for the stimulation of hair growth.
Patent NZ-584476-A (NZ)
Title: Electric power cable connector for spacing transmission lines
Inventor: THOMPSON ANDREW JAY
IPC: H02G1/02
Filed: 2010-04-07
Abstract: A connector (10) for securing a high voltage electrical power cable (14) to a spreader rod (16) is disclosed. The connector has a body comprising a securing portion (18) arranged to secure to the spreader rod. First and second legs extend on either side of the body, each of the legs having a cable support with an abrasion resistant surface. At least one of the legs is resiliently biased relative to the body so that in use the leg urges the supported portion of cable towards the spreader rod.
Patent NZ-587795-A (NZ)
Title: Bombesin analog peptide antagonist conjugates
Inventor: MAECKE HELMUT
IPC: C07K7/08
Filed: 2009-02-27
Abstract: Provided is a bombesin analog peptide antagonist conjugate having general formula (1) [A-(B)n]x-C, wherein x is an integer from 1 to 3, n is an integer from 1 to 6, A is a metal chelator comprising at least one radionuclide metal, B is a spacer linked to N-terminal of C or a covalent bond, C is a bombesin analog peptide antagonist of sequence C-1 to C-3, wherein: C-1 is Xaa16 -Gln7-Trp8-Ala9-Val10-Xaa211-His12-Xaa313-Xaa414-ZH or C-2 is Xaa16 -Gln7-Trp8-Ala9-Val10-Xaa211-His12-Leupsi(CHOH-CH2)-(CH2)2)-CH3 or C-3 is Xaa16 -Gln7-Trp8-Ala9-Val10-Xaa211-His12- Xaa513-Xaa614-ZH, with defined substituents for Xaa. The metal chelator can be for trivalent or for pentavalent metals and can be selected from DOTA, NODASA, NODAGA, NOTA, DTPA, EDTA, TETA and TRITA. The compounds are useful for inhibiting bombesin receptors and gastrin releasing peptide receptors and can be used for radiolabeling and imaging various tumours.
Patent NZ-588352-A (NZ)
Title: Medical effector system
Inventor: BRUGGEMAN PAUL J
IPC: G16H10/60
Filed: 2005-08-24
Abstract: A medical effector system comprises a) a microprocessor-based bedside monitoring unit; b) a microprocessor-based procedure room and C) an umbilical cable. The microprocessor-based bedside monitoring unit has a bedside-monitoring unit host controller, has a first series of connection points for receiving patient inputs from patient monitoring connections has a second series of connection points for outputting patient outputs based on the received inputs, and has a display screen for displaying at least some of the patient outputs. a microprocessor-based procedure room unit having a medical effector, and The microprocessor-based procedure room has a medical effector, has a drug-delivery flow control assembly and a procedure-room-unit host controller with a memory containing a patient-monitoring and end-effector-scheduling program which is operatively connected to program inputs based at least in part on at least some of the patient outputs and controls, and/or advises a user to control, the medical effector based at least in part on the program inputs. The procedure room unit (PRU) has an individual PRU identifier and the bedside monitoring unit (BMU) has an individual BMI identifier. The umbilical cable has a first end attached or attachable to the second series of connection points of the bedside monitoring unit and has a second end attached or attachable to the procedure room unit. At least one of the first and second ends is detachable from the corresponding bedside monitoring unit or the procedure room unit, and the procedure-room-unit host controller and the bedside-monitoring unit host controller are operatively connected together when the umbilical cable is attached to the procedure room unit and the bedside monitoring unit.
Patent NZ-591544-A (NZ)
Title: Improved method of rna display
Inventor: HSIEH CHUNG-MING
IPC: G01N33/53
Filed: 2009-09-30
Abstract: Disclosed is a method of screening an scFv antibody RNA display library, the method comprising the steps of: (a) providing a puromycin or analogue thereof crosslinked single chain Fv (scFv) mRNA molecule, said molecule comprising an mRNA encoding a 5' scFv and a 3' spacer sequence, which molecule is crosslinked to a single stranded nucleic acid linker, the linker comprising a puromycin, or analogue thereof, at a 3' end and a Psoralen C6 at a 5' end; (b) in vitro translating the puromycin-crosslinked scFv mRNA molecule in the presence of a label under mildly reducing conditions such that a labeled puromycin-crosslinked scFv mRNA/protein molecule is formed; (c) purifying the labeled puromycin-crosslinked scFv mRNA/protein molecule; (d) subjecting the purified labeled puromycin-crosslinked scFv mRNA/protein molecule to antigen selection with at least one antigen; and (e) recovering the purified labeled puromycin-crosslinked scFv mRNA/protein molecules using affinity based magnetic beads.
Patent NZ-602234-A (NZ)
Title: A Cushioning System with a flexible sheet support and adjustable attachable padding cells to provide contoured padding
Inventor: SCARLETT ROUAND JAMES MORTIMER
IPC: A47C27/16
Filed: 2012-09-04
Abstract: 602234 Disclosed is a cushioning system for relieving pressure sores for wheelchair users. The system comprises a flexible sheet support, a plurality of padding cells of differing sizes and containing air and/or foam; and attachment means of hook and loop fasteners, associated in part with the sheet support and in part with the padding cells. The system is formed such that the cells are detachably engageable with the sheet support by way of the attachment means, and the number and size of cells is sufficient to enable a user to adjustably assemble cells with respect to the support sheet to provide contoured padding for at least part of the human body. The sheet support and the padding cells together provide a detachable cushion.
Patent NZ-603567-A (NZ)
Title: Crystalline ingenol mebutate
Inventor: OGBOURNE STEVEN MARTIN
IPC: A61K31/22
Filed: 2011-04-18
Abstract: ABSTRACT - 603567 The disclosure relates to a crystalline form of ingenol mebutate, methods of preparation thereof, and to its use. More specifically, the disclosure relates to the conversion of amorphous ingenol mebutate (ingenol-3-angelate, PEP005) to a crystalline form, which was characterized by single crystal X-Ray crystallography (XRC), attenuated total reflectance Fourier transform infrared (FTIR-ATR) spectroscopy and Differential Scanning Calorimetry (DSC). The crystalline form of ingenol mebutate is suitable for treating a wart, photodamage, actinic keratosis, superficial basal cell carcinoma and cancer or other condition involving neoplastic cells.
Patent NZ-605315-A (NZ)
Title: Lighting assembly for ceiling board
Inventor: WONG CHEE KEAT
IPC: F21V17/00
Filed: 2011-07-22
Abstract: A ceiling, in particular a ceiling board, with modularized composite LED lamps. The ceiling comprises a light bar (2), a ceiling board (1a, 1b). The ceiling is characterized in that a plurality of LED lamps are fixedly embedded in a light bar; the bar is mounted on the side edges of two adjoining ceiling boards fitted and held firmly by the standard ceiling grids.
Patent NZ-607743-A (NZ)
Title: Method and device for network traffic manipulation
Inventor: ORNAGHI ALBERTO
IPC: H04L29/08
Filed: 2010-08-03
Abstract: Disclosed is a method for manipulating the data traffic related to a target (20’) connected to a data communications network whose elements communicate according to the HTTP protocol. The method includes: - Passively intercepting, on the part of a traffic manipulation device (50) which comprises a proxy, a first HTTP request that originates from said target (20’). The first HTTP request comprises a first domain associated with a server (60) and a requested resource; - Sending, on the part of said manipulation device (50), a first HTTP response related to the first HTTP request. The first HTTP response comprises redirection instructions which in turn comprise a second domain; - Passively intercepting, on the part of the traffic manipulation device (50), a DNS query toward a DNS server (70) that originates from the target (20’). The first DNS query comprises a query to resolve the second domain with an IP address; - Sending, on the part of the manipulation device (50), a DNS response related to the DNS query. The first DNS response comprises the resolution of the second domain with the IP address of the proxy; - Receiving (10), on the part of the proxy, a second HTTP request that originates from the target (20’). The second HTTP request comprises the second domain and the requested resource; - Sending, on the part of the proxy, a third HTTP request toward the server (60). The third HTTP request comprises the first domain and the requested resource; - Receiving, on the part of the proxy, a second HTTP response originating from the server (60) and related to the third HTTP request. The second HTTP response comprises the requested resource; - Modifying, on the part of the proxy, the requested resource; and - Sending, on the part of the proxy, a third HTTP response to the target (20’). The third HTTP response comprises the modified resource.
Patent NZ-615210-A (NZ)
Title: Azole derivative
Inventor: ONO NAOYA
IPC: A61K31/506
Filed: 2012-03-15
Abstract: Provided are: a novel compound which binds to FKBP12 or a pharmaceutically acceptable salt thereof; and a novel therapeutic agent which contains the compound or a pharmaceutically acceptable salt thereof and is useful for the prophylaxis or treatment of alopecia. Specifically provided is a compound which is represented by formula (1) or a pharmaceutically acceptable salt thereof. (In formula (1), R represents a group represented by formula (2) or formula (3).) Compounds of the invention include: (S)-1-(2-(5-((3,4-dimethoxyphenoxy)methyl)-1,3,4-thiadiazol-2-yl)pyrrolidin-1-yl)-2,2-difluoro-2-(1-hydroxy-3,3,5,5-tetramethylcyclohexyl)ethanone, (S)-1-(2-(5-((3,4-dimethoxyphenoxy)methyl)-4H-1,2,4-triazol-3-yl)pyrrolidin-1-yl)-2,2-difluoro-2-(1-hydroxy-3,3,5,5-tetramethylcyclohexyl)ethanone, (S)-1-(2-(5-((3,4-dimethoxyphenoxy)methyl)oxazol-2-yl)pyrrolidin-1-yl)-2,2-difluoro-2-(1-hydroxy-3,3,5,5-tetramethylcyclohexyl)ethanone, (S)-1-(2-(5-((3,4-dimethoxyphenoxy)methyl)thiazol-2-yl)pyrrolidin-1-yl)-2,2-difluoro-2-(1-hydroxy-3,3,5,5-tetramethylcyclohexyl)ethanone, and (S)-2,2-difluoro-2-(1-hydroxy-3,3,5,5-tetramethylcyclohexyl)-1-(2-(5 -((pyrimidin-5-yloxy)methyl)isoxazol-3-yl)pyrrolidin-1-yl)ethanone.
Patent NZ-617621-A (NZ)
Title: Systems and methods for evacuating materials at a surgical site
Inventor: SCHULTZ LEONARD S
IPC: B08B15/04
Filed: 2012-04-19
Abstract: Disclosed is an evacuation apparatus for a surgical site. The apparatus comprises a housing (22) having a top surface (24), a bottom surface spaced from the top surface, and an outer side wall (28) extending at least partially between the top and bottom surfaces. The top surface, the bottom surface and the outer sidewall define an inner cavity (32) of the housing. An access opening (34) extends between the top surface and the bottom surface. An inner facing (36) is provided along a perimeter of the access opening. A generally porous support material is positioned adjacent to or in the inner cavity such that the support material resists the collapse of the housing. The inner cavity is provided in fluid communication with the access opening via the inner facing. One or more ingress apertures (38, see also 103; figure 2), formed in the outer side wall (28), are provided in fluid communication with the access opening. A filter media is positioned adjacent to or in the inner cavity, and is distinct from and outside the support material, such that a flow of fluid through the ingress apertures moves through the filter media. A vacuum source (14) is provided in fluid communication with the inner cavity to draw surgical byproduct into the inner cavity.
Patent NZ-620415-A (NZ)
Title: Cartridge and printing material supply system
Inventor: KODAMA HIDETOSHI
IPC: B41J2/175
Filed: 2012-12-26
Abstract: An inkjet printer cartridge (20) with angled electrical terminals (40) is described. The cartridge interlocks with a slot in a printer by way of a first locking portion (810) and a second locking portion (620), the second being higher on the body of the cartridge than the first. The first locking portion is designed to interact with a rotating lever.