baber/WOPTO huggingface dataset:
Patent AU-2016213759-A1 (AU)
Title: Transdermal delivery systems of peptides and related compounds
Inventor: YU CHONGXI
IPC: C07C323/22
Filed: 2016-08-10
Abstract: TRANSDERMAL DELIVERY SYSTEMS OF PEPTIDES AND RELATED COMPOUNDS Abstract RXF.- Y, Xj N R z n Structure 1 The novel positively charged pro-drugs of peptides and related compounds in the general formula (1) 'Structure 1' were designed and synthesized. The compounds of the general formula (1) 'Structure 1' indicated above can be prepared by standard peptide synthesis protocols. The positively charged amino group of the pro-drug of peptides not only makes the drugs soluble in water, but also bonds to the negative charge on the phosphate head group of membranes and pushes the pro-drug into the cytosol. The lipophilic portion (by modification of the polar groups with lipophilic alkyl groups) of the prodrugs will facilitate the entering of the drugs into the skin membrane. The results suggest that the pro-drugs diffuses through human skin -100 1000 times faster than do peptides and related compounds. In plasma, more than 40% of these pro-drugs can change back to the parent drugs in a few minutes. The prodrugs can be used medicinally in treating any peptides and related compounds-treatable conditions in humans or animals. The prodrugs can be administered transdermally for any kind of medical treatments and avoid proteolysis by proteolytic enzymes in the GI tract. Controlled transdermal administration systems of the prodrug enables peptides and related compounds to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of peptides and related compounds. Another great benefit of transdermal administration of these pro-drugs is that administering medication, especially to children, will be much easier.
Patent AU-2016219170-A1 (AU)
Title: Antibody therapeutics that bind CTLA4
Inventor: GRAY JOHN DIXON
IPC: C07K16/28
Filed: 2016-02-12
Abstract: The present disclosure provides compositions and methods and kits relating to anti-CTLA4 antibodies. More specifically, fully human antibodies that bind CTLA4, CTLA4-antibody binding fragments and derivatives of such antibodies, and CTLA4-binding polypeptides comprising such fragments are provided. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating a disease requiring either stimulation of immune responses or suppression. In one aspect, the present disclosure provides an isolated fully human anti-CTLA4 antibody of an IgG class that binds to a CTLA4 epitope with a binding affinity of at least 10
Patent AU-2016228132-A1 (AU)
Title: Used oil recycling pretreatment and filtration assembly
Inventor: KUTOWY OLEH
IPC: B01D36/04
Filed: 2016-03-02
Abstract: A filtration system suitable for recovering base stock from used lubricating oil and other applications passes feedstock over nano-filtration membranes in a serpentine flow. Pressure boosters installed in the openings separating consecutive stacks serve to restore lost pressure of the feedstock. As pretreatment a "knocking" non-blinding filter separates particulates from a feedstock by a knocking action that dislodges particulate matter which has come to rest on the screen. Further pretreatment includes a vacuum evaporator for flash evaporation of volatile components from a liquid and effecting the extraction of water and glycol from used engine lubricating oil. The liquid is heated or cooled when flowing over some of the surfaces to adjust for heat lost or acquired during exposure of the liquid surface to a gas or vacuum. Liquid moves on the surface of the discs under centrifugal force or a wiper blade guides the liquid as it moves over the support surface.
Patent AU-2016242282-A1 (AU)
Title: Intra-oral device for upper airway support
Inventor: HADAS NOAM
IPC: A61F5/56
Filed: 2016-03-27
Abstract: A device reduces breathing obstructions of a user. A base member removably couples to the upper or lower jaw of the user. An elastic support member couples to the base member and includes at least one contact surface for contacting at least one region of tissue. The elastic support; member moves between a retracted state and a deployed state, in the retracted state, the at least one contact surface spatially separates from the at least one region of tissue. In the deployed state, at least a portion of the elastic support member extends such that the at least one contact surface contacts the at least one region of tissue preventing at least partial collapse of at least a section of the upper airway. A control unit actuates an electro-mechanical drive arrangement to move the elastic support member between the retracted and deployed states.
Patent AU-2016260324-A1 (AU)
Title: Radio frequency identification tag delivery system
Inventor: OWNBY JOHN FIELDING
IPC: E21B34/14
Filed: 2016-05-13
Abstract: A system for operating a downhole tool includes a tag carrier; a RFID tag coupled with the tag carrier; and a control sub having a bore extending therethrough, the control sub comprising: an antenna located adjacent to the bore; and a stop for catching the tag carrier, wherein: the radio frequency identification tag is coupled with the tag carrier in relation to the stop and the antenna such that the radio frequency identification tag is aligned with the antenna when the tag carrier is caught in the stop, and the stop is operable to allow passage of the tag carrier through the stop after the tag carrier is caught by the stop.
Patent AU-2016297308-A1 (AU)
Title: Composition for stabilizing radiochemical purity of [18F]fluoro-dopa and method for preparing same
Inventor: LEE SANG JU
IPC: A61K51/04
Filed: 2016-07-22
Abstract: The present invention relates to a composition for stabilizing the radiochemical purity of [
Patent AU-2016298238-A1 (AU)
Title: Cooking appliance with direct contact cooking grate
Inventor: EVERETT JR DAVID WILLIAM
IPC: A47J37/10
Filed: 2016-07-26
Abstract: In a cooking appliance, the appliance generally includes at least one cooking grate having a first rail, a second rail, and a plurality of rods extending between the first and second rails in spaced relationship with each other, each of the plurality of rods having a respective heating element such that the at least one cooking grate facilitates directly contacting a food product with a plurality of the heating elements during cooking.
Patent AU-2016413311-A1 (AU)
Title: Absorbent article
Inventor: MIYAMA TAKUYA
IPC: A61F13/514
Filed: 2016-07-01
Abstract: The present invention provides an absorbent article using a cotton-containing nonwoven fabric as a surface sheet. The absorbent article causes hardly any discomfort, such as the feeling of being wet or sweaty, to a wearer thereof, and hardly causes skin irritation. In the absorbent article according to the present invention, a surface sheet (2) thereof is a nonwoven fabric which comprises at least two fiber layers including a first fiber layer (201) composed of cotton and thermoplastic resin fibers and a second fiber layer (202) composed of hydrophobic thermoplastic resin fibers. The nonwoven fabric is provided with: multiple protrusions (11) that protrude in the direction of a first surface (2a); and multiple recesses (12) that are each disposed between adjacent protrusions (11) so as to be indented in the direction of a second surface (2b), wherein the protrusions (11) each have a void part (14) opposite to the second surface (2b), and the nonwoven fabric exhibits weak acidity at least in the protrusions (11).
Patent AU-2017200680-A1 (AU)
Title: Method and apparatus for entropy coding video and method and apparatus for entropy decoding video
Inventor: KIM IL-KOO
IPC: H04N19/119
Filed: 2017-02-01
Abstract: Abstract Disclosed is a method for entropy coding and decoding a video. The method for entropy decoding the video comprises: obtaining from a bitstream a conversion unit valid coefficient flag, which indicates whether a conversion coefficient that is not 0 exists in a conversion unit; 5 determining a context model for arithmetic decoding the conversion unit valid coefficient flag, on the basis of conversion depth of the conversion unit; and arithmetic decoding the conversion unit valid coefficient flag on the basis of the context model that is determined.
Patent AU-2017204887-A1 (AU)
Title: Compounds and methods for enhancing erythropoiesis
Inventor: WU RONG-TSUN
IPC: A61P11/00
Filed: 2017-07-14
Abstract: Compounds and methods for enhancing erythropoiesis are provided. The compound comprises a chemical structure of the formula (I) indicated below, in which R is a glycosyl group. In addition to having an erythropoiesis effect, the compound of the formula (I) is effective in 5 enhancing erythropoietin formation, and increasing kidney function and expression of hepatocyte growth factor. The method includes the step of administering an effective amount of the compound of the formula (I) to a subject in need thereof and thereby results in an enhancement of erythropoiesis. (I) 0 -OH
Patent AU-2017235599-A1 (AU)
Title: Combination of drugs having different potency
Inventor: STOMBERG CARMEN
IPC: A61K9/24
Filed: 2017-03-17
Abstract: The invention relates to a three- dimensionally printed pharmaceutical dosage form comprising a first pharmacologically active ingredient and a second pharmacologically active ingredient; wherein the relative weight ratio of the first pharmacologically active ingredient to the second pharmacologically active ingredient in the pharmaceutical dosage form is within the range of from 10,000 : 1 to 1 : 1. The invention also relates to a process for the preparation of such pharmaceutical dosage form by three- dimensional printing, preferably by fused deposition modeling.
Patent AU-2017238392-A1 (AU)
Title: Mannose-derived antagonists of FimH useful for treating disease
Inventor: JANETKA JAMES W
IPC: C07H15/26
Filed: 2017-03-23
Abstract: The present invention relates to mannoside derivative compounds useful as inhibitors of FimH and methods for the treatment or prevention of urinary tract infection.
Patent AU-2017243431-A1 (AU)
Title: Device for the continuous and discriminated positioning of each blade of hydraulic turbines at vertical axis
Inventor: TULINO ROSARIO ROCCO
IPC: F03B17/06
Filed: 2017-03-28
Abstract: Device for the continuous positioning of each blade of free flow hydraulic turbines at vertical axis with instant impact angular positions always optimal for any different stream speed. Two coplanar floating disks connected to a levers system controlled by three separated electrical stepper motors compose the device. On varying the water stream speed blades specific paths happens along the orbital path of rotating barrel. The blades are equidistant placed at the edge of rotating barrel, while the electrical stepper motors are fixed to the external frame of the hydraulic turbine.
Patent AU-2017257978-A1 (AU)
Title: Blood cell lysis reagent
Inventor: GAO KUI
IPC: G01N33/50
Filed: 2017-04-26
Abstract: Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.
Patent AU-2017267543-A1 (AU)
Title: Access system and container for communal objects
Inventor: JUST PETER
IPC: G07C9/00
Filed: 2017-05-17
Abstract: Described are methods and systems for accessing shared communal objects. A physical object container holds and protects the objects, keeping them secure and protected for future use. The object container senses the state and status of the objects contained within it. The object container is only openable by authorized users. An information infrastructure backend coordinates the scheduling and usage of objects stored within the object container.
Patent AU-2017272356-A1 (AU)
Title: Compositions and methods for the treatment of human papillomavirus (HPV)-associated diseases
Inventor: JONES FRANK R
IPC: C12N15/12
Filed: 2017-06-02
Abstract: Methods and compositions for constructing and producing recombinant adenovirus- based vector vaccines are provided. In particular aspects, there are be provided compositions and methods involving adenovirus vectors comprising genes for target antigens, such as novel antigens of HPV E6 and/or HPV E7 for use in treatment methods that generate highly reactive anti-HPV and anti-tumor immune responses in subjects with preexisting immunity to adenovirus.
Patent AU-2017279650-A1 (AU)
Title: A stump height adjustment mechanism
Inventor: POPE AARON
IPC: E02D35/00
Filed: 2017-12-20
Abstract: Abstract There is provided a stump height adjustment mechanism which may be used for subfloor supportive stump stumping or restumping to account for I'd variations which may be caused by soil movement, house renovations and the like without requiring hitherto conventionally utilised packing. The mechanism may comprise a rectangular member; opposing side plates extending down from the rectangular member such that the rectangular member defines a lower face for resting on a top surface of a stump and the side plates define opposing inner faces for fastening against respective side surfaces of the stump adjacent the top surface. A height adjustable vertical threaded rod may extend upright through the rectangular member to support a bearer pressure plate at an upper end thereof. Figure 1
Patent AU-2017286888-A1 (AU)
Title: Technologies for managing application configurations and associated credentials
Inventor: MELLIERE PAUL L
IPC: G06F15/16
Filed: 2017-06-29
Abstract: Technologies for managing application configurations and associated credentials of a unified collaboration application include a centralized hub computing device configured to install an integration of a cloud-based application and establish a link the integration to a unified collaboration application. To do so, the centralized hub computing device is configured to receive configuration input for the integration from a user, store the configuration in an input application configuration database of the centralized hub computing device, and enable the application integration such that a communication channel can be established between the integration and the unified collaboration application via the centralized hub computing device. Additional embodiments are described herein.
Patent AU-2017310027-A1 (AU)
Title: Combination therapy for cancer
Inventor: LO KIN-MING
IPC: A61K39/395
Filed: 2017-08-11
Abstract: This invention relates generally to a combination therapy for the treatment of cancer, particularly to a combination of (i) a bifunctional molecule comprising a TGFßRII or fragment thereof capable of binding TGFß and an antibody, or antigen binding fragment thereof, that binds to an immune checkpoint protein, such as Programmed Death Ligand 1 (PD-L1) and (ii) at least one additional anti-cancer therapeutic agent.
Patent AU-2017317568-A1 (AU)
Title: Tagged nucleotides useful for nanopore detection
Inventor: TRANS ANDREW
IPC: G01N27/327
Filed: 2017-08-24
Abstract: The present disclosure relates to compounds comprising a negatively-charged polymer moiety which is capable of entering a nanopore and upon entering a nanopore in the presence of positive ions results in an increased flow of the positive ions through the nanopore. The present disclosure provides methods of preparing the compounds and for their use as nanopore-detectable tags, in particular, for nanopore-based nucleic acid detection and sequencing.
Patent AU-2017319596-A1 (AU)
Title: Computer implemented method, welding system and apparatus for multiple application banks
Inventor: Rickfjord Stefan
IPC: B23K31/00
Filed: 2017-08-30
Abstract: Various embodiments are generally directed to techniques for selecting among multiple application software modules by a bootloader (114) of a welding or cutting system (102). Techniques described herein includes a bootloader component (114) of a welding system (102) to determine that more than one application software module is available for the welding system (102). A display device (110) is configured to display user interface components configured to allow user selection of one or more application software module. An input device is configured to receive a selection of one of the one or more application software modules. A processor (106) of the welding system (102) is configured to execute the selected one or more application software modules.
Patent AU-2017323183-A1 (AU)
Title: Method for transmitting sonar data to an evaluation unit of a sonar system of an underwater vehicle and sonar system therefor
Inventor: ISSERSTEDT THORSTEN
IPC: G01S5/18
Filed: 2017-08-08
Abstract: The present invention comprises a method for transmitting sonar data (60) to an evaluation unit (24) of a sonar system (10) of an underwater vehicle, comprising the following steps: Converting ultrasonic waves to hydrophone signals (52) by means of a plurality of hydrophones (14); Converting (42) the hydrophone signals (52) to sonar data (60) by means of at least one microcontroller circuit (18), transmitting (44) the sonar data (60) to an evaluation unit (24), and evaluating (48) the sonar data (60) in the evaluation unit (24), the conversion (42) of the hydrophone signals (52) comprising the steps of digitizing (44) and compressing (58) the hydrophone signals (52) and the compression method (68) used during the compressing (58) being changed or varied by the microcontroller circuit (18) depending on the hydrophone signals (52). The invention further relates to a sonar system (10) for an underwater vehicle for receiving and evaluating underwater sound.
Patent AU-2017339555-A1 (AU)
Title: Manufacture of snack food chips
Inventor: BHASKAR AJAY RAJESHWAR
IPC: A23L7/13
Filed: 2017-10-06
Abstract: A method of manufacturing snack food chips, the method comprising the steps of: i. providing a first starch-containing component which comprises a cold water swelling starch, a second starch-containing component which comprises substantially ungelatinized starch, and a third starch-containing component which comprises corn masa flour; ii. forming a dough from a mixture of the first, second and third starch-containing components and water, wherein the dough comprises from 35 to 75 wt% corn masa flour, from 10 to 40 wt% of the second starch-containing component, and from 5 to 30 wt% of the first starch-containing component, each based upon the weight of dry ingredients of the dough, and the dough comprises from 25 to 35 wt% added water, based on the weight of the dough, wherein the dough is formed at a temperature of up to 30 °C by mixing dry ingredients of the dough with water for a period of from 3 to 60 seconds and the cold water swelling starch forms a gel matrix in the dough; iii. forming a dough sheet from the dough, wherein the dough sheet has a thickness of from 0.5 to 1.5 mm; iv. cutting a plurality of dough pieces from the dough sheet; and v. cooking the dough pieces to form a plurality of snack food chips.
Patent AU-2017345501-A1 (AU)
Title: Sonotrode and anvil for ultrasonic welding of plastics, method for producing a plastic container
Inventor: DE CUYPER DIRK
IPC: B29C65/08
Filed: 2017-10-18
Abstract: Combination of a sonotrode (1) and anvil (20), comprising a sonotrode/anvil surface (3, 21) and a first row of sonotrode/anvil welding contact elements (4, 22), whereby aforesaid first/second series of each aforesaid sonotrode/anvil welding contact element of a first row (11, 30) comprises a first/second adapted lateral surface (12, 31) that joins at least one part of aforesaid first/second plateau surface (9, 27) with at least one part of aforesaid sonotrode/anvil surface side (5, 23), whereby aforesaid first/second adapted lateral surface (12, 31) comprises a first/second curved surface (13, 32) positioned between aforesaid first/second plateau surface (9, 27) and aforesaid first/second substantially straight surface (14, 29), whereby aforesaid first/second curved surface (13, 31) has a convex outward arch. The welding contact element (4) is positioned in relation to aforesaid anvil welding contact element (22) such that aforesaid sonotrode welding contact element (4) is positioned during welding next to aforesaid anvil welding contact element (22) and is provided to form at least one part of a weld seam (80).
Patent AU-2017349496-A1 (AU)
Title: Metal recovery process
Inventor: BARKER WILL
IPC: C02F1/28
Filed: 2017-10-31
Abstract: The invention relates to a process for recovering metals from aqueous solutions or solid feedstocks such as ores and waste. In particular, the invention relates to a method of recovering a target metals using a microorganism.
Patent AU-2017361526-A1 (AU)
Title: Liquid allergen compositions and methods for making the same
Inventor: DOMBKOWSKI ASHLEY
IPC: A61K9/00
Filed: 2017-11-21
Abstract: Liquid mixed allergen compositions of two or more different allergens are provided. Also provided are methods of making liquid mixed allergen compositions and administering a liquid mixed allergen composition to a subject.
Patent AU-2017362598-A1 (AU)
Title: Medicament delivery device adapted for long term storage
Inventor: BOSTRÖM ANDERS
IPC: A61M5/20
Filed: 2017-10-30
Abstract: The present invention relates to a medicament delivery device comprising a housing (10); a medicament container holder (60) arranged to accommodate a medicament container (62) provided with a medicament delivery member (64); a power unit (81) arranged to act on said medicament container (62) for expelling a dose of medicament when activated; an activation mechanism (30, 48, 148) operably connected to said power unit (81), capable of activating said power unit; said activation mechanism (30, 48, 148) comprising a medicament delivery member guard (30) movable in a longitudinal direction in relation to said housing (10); said activation mechanism comprising a force element (148) arranged to bias said medicament delivery member guard (30) to a proximal extended position wherein said medicament delivery member (64) is covered; locking mechanism (40, 160) operably arranged to lock said medicament delivery member guard (30) in the extended position; that said locking mechanism (40, 160) comprises a number of locking elements (40) connected to said medicament delivery member guard (30) and flexible in a generally radial direction, that said locking mechanism further comprises a number of ledge surfaces (160) connected to said housing, wherein said locking elements (40) flex radially outwards and abut said ledge surfaces (160) when said medicament delivery member guard (30) is moved in the extended position, preventing any further movement of said medicament delivery member guard (30) in the distal direction. The invention is characterised by spaces (158) connected to said housing (10) in which said locking elements (40) are positioned in a non-tensioned state in a delivery mode of said medicament delivery device.
Patent AU-2017364814-A1 (AU)
Title: Keratin fiber treatment composition
Inventor: DOI RYOSUKE
IPC: A61Q5/06
Filed: 2017-11-28
Abstract: The purpose of the present invention is to provide a keratin fiber treatment composition that is capable of retaining the shape (style) of keratin fibers over an extended period of time and that also has an exceptional feel on use. The present invention pertains to a keratin fiber treatment composition characterized by containing a sugar alcohol. This keratin fiber treatment composition preferably also contains one or both urea and/or a urea derivative or a hair-styling resin. The pH of this keratin fiber treatment composition is preferably within the range of 4.0-7.5.