baber/WOPTO huggingface dataset:
Patent CA-2348529-A1 (CA)
Title: Conductance of improperly folded proteins through the secretory pathway
Inventor: EGAN MARIE E
IPC: A61K9/12
Filed: 1999-10-27
Abstract: This invention provides the methodology and agents for treating disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particularly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins. In particular, thapsigargin, cyclopiazonic acid, DBHQ or halothane can be used to allow the release of .DELTA.F508CFTR or of a secretion-incompetent variant null (Hong Kong) of .alpha.1-antitrypsin, in order to treat cystic fibrosis or chronic obstructive pulmonary disease (pulmonary emphysema) respectively.
Patent CA-2350868-A1 (CA)
Inventor: EBERTS DEBRA
IPC: A23K1/18
Filed: 2001-06-18
Abstract: A diet for mass rearing of insects that feed on hard, woody plant tissue, e.g., beetles including weevils that feed on hard, woody plant tissue, comprises a homogeneous mixture of first portion which is subjected to sterilization in an autoclave comprising water, agar and salt mix and optionally also yeast extract, casein and a sugar, and of a second portion which is not subjected to sterilization in an autoclave which comprises host plant part fed on by insect larvae, vitamin mix, and antimicrobial agent(s). A method for mass rearing of insects that feed on hard, woody plant tissue, e.g., weevils, e.g., Hylobius transversovittatus or Cyphocleonas achates Fahraeus, comprises placing first instar insect larvae on an artificial diet comprising ground host plant part, incubating the larvae on the diet in darkness at a temperature ranging from 15 to 30°C and a relative humidity ranging from 50 to 90%, and retrieving adults as they emerge.
Patent CA-2352932-A1 (CA)
Title: Customizable and upgradable devices and methods related thereto
Inventor: ESCOBOSA MARCUS
IPC: G08C19/28
Filed: 2001-07-11
Abstract: A customizable and an upgradable remote control is provided which may be customized or upgraded via a Web site or through other remote, and preferably interactive, processes. A database is provided which includes a plurality of functions of a consumer electronic device, such as a T.V. or and DVD player. A user selects among the plurality of functions at least one of the desired functions. In response to the user selection a virtual configuration is created to virtually configure the customized remote control. The virtual configuration may be downloaded to the customizable remote control. Preferably, the customizable remote control is provided with a plurality of preprogrammed standard keys and a plurality of configurable keys. A plurality of customized labels corresponding to the plurality of configurable keys may be provided separately or printed as part of the virtual configuration download process. More generally methods for providing a customized consumer electronic device are disclosed, including a preferred embodiment using a touch screen remote control. In one embodiment a database of command codes operable with a hand-held device is maintained. A user is allowed to access the database via a Web site.  The user may then download at least one of the plurality of command codes provided in the selection. The hand-held device may also be utilized in an interactive environment. Such an interactive environment may include pay-per-event access, and the like.
Patent CA-2354435-A1 (CA)
Title: Etablissement a distance de reglage automatique, au moyen de formules et parametres de jeux, par exemple a partir d'un terminal d'administration
Inventor: KLAYH JOHN
IPC: A63F13/12
Filed: 1999-12-16
Abstract: L'invention concerne un système de commande de jeu automatique comprenant : un jeu automatique comportant des pièces de jeu virtuel, manipulées lors du jeu, ainsi qu'un logiciel et matériel de commande, destinés à afficher et commander les pièces de jeu virtuel, un terminal d'administration destiné à entrer et conserver des paramètres se rapportant au jeu, ainsi qu'un réseau de téléchargement de paramètres, du terminal d'administration vers le jeu, le fonctionnement de ce jeu, comprenant des programmes logiciels et câblés conservés au niveau d'un emplacement différent du terminal d'administration, étant commandé par lesdits paramètres.
Patent CA-2356565-A1 (CA)
Inventor: DHAIDAN FALEH GH
IPC: B60R7/08
Filed: 2001-08-17
Abstract: The purpose of this invention is to solve and provide a convenient location for the Kleenex boxes in vehicles.
Patent CA-2357993-A1 (CA)
Inventor: SAKNO MICHAEL P
IPC: B28B23/00
Filed: 2001-09-18
Abstract: A cast-in-place coupling is positioned on concrete forms by detachable attachment means. The coupling may have breakaway tabs or may be frictionally engaged to a fitting fastened to a form. After concrete is poured the attachment means is separated from the coupling with minimum effort and inconvenience.
Patent CA-2361028-A1 (CA)
Title: Optical fiber and optical transmission line using the optical fiber
Inventor: TAMURA JUNICHI
IPC: G02B6/036
Filed: 2001-11-05
Abstract: An optical fiber for forming an optical transmission line suitable for the wavelength division multiplexing transmission by connecting to a positive dispersion optical fiber is provided. Outside a first glass layer (1), a second glass layer (2), a third glass layer (3) and a fourth glass layer (4) are sequentially disposed. The fourth glass layer (4) is to be a reference layer for a standard of a refractive index. A relative refractive index difference .DELTA.1 of the first glass layer to the reference layer is set 1.6% to 2.6%, inclusive, a relative refractive index difference .DELTA.2 of the second glass layer is set -0.65% to -0.4%, inclusive, and a relative refractive index difference .DELTA.3 of the third glass layer is set 0.15% to 0.5%, inclusive. A relationship among an outer diameter d1 of the first glass layer, an outer diameter d2 of the second glass layer and an outer diameter d3 of the third glass layer is set 2.5 <= (d2/d1) <= 3.0, and 1.5 <=  (d3/d2) <= 3Ø
Patent CA-2361645-A1 (CA)
Inventor: DITRICH KLAUS
IPC: C07C59/125
Filed: 2000-01-29
Abstract: Nouveau procédé de préparation d'esters de formule générale (I), à partir de composés contenus dans des solutions aqueuses, de formule générale (II), caractérisé en ce que (a) les composés de formule générale (II) sont extraits directement ou après avoir été séparés de leurs sels, en présence d'un alcool C1 à C8 et d'un solvant non miscible avec de l'eau, et (b) lesdits composés sont estérifiés en présence d'un catalyseur et d'un agent d'entraînement dans des conditions de distillation azéotrope avec un alcool C1 à C8, les étapes (a) et (b) pouvant être soit séparées concernant le temps et le lieu, soit menées dans une séquence à suite continue ou discontinue. Dans les formules (I) et (II), les substituants possèdent la signification suivante: R<1> = F, Cl, -OH, -O-alkyle C1-C10, R<2> = H, alkyle C1-C10, R<3> = alkyle C1-C8, Q = -OH, -O<-> K<+>, K<+> étant un cation alcalin ou alcalino-terreux, et n = 0, 1 ou 2.
Patent CA-2363079-A1 (CA)
Title: Formulations of hair cosmetics
Inventor: SANNER AXEL
IPC: C08G77/442
Filed: 2000-02-10
Abstract: The invention relates to the use of polymers which can be obtained by radical polymerisation of a) at least one vinyl ester of C1-C24-carboxylic acids in the presence of b) compounds containing polyether and c) optionally, one or more other copolymerisable monomers, followed by the at least partial saponification of the ester functions of the original monomers a), in formulations of hair cosmetics.
Patent CA-2363620-A1 (CA)
Inventor: SHAFER TERRY W
IPC: F04D29/44
Filed: 2001-11-22
Abstract: An electrical submersible well pump assembly has an inducer and diffuser for applying a positive pressure to the first pump stage. The pump assembly includes a centrifugal pump with a housing having a well fluid inlet and a number of pump stages. Each pump stage has an impeller and a diffuser. An inducer is mounted in the housing upstream of the impeller of the first pump stage. The inducer has a helical flight that is rotatable in unison with the pump. A diffuser is positioned between the inducer and the impeller of the first stage.
Patent CA-2364661-A1 (CA)
Inventor: LYDON RICHARD
IPC: G06K7/14
Filed: 2000-02-22
Abstract: A bar code scanning system and method for scanning a bar code (20) containing a key including successively scanning the bar code (20) and providing, for each scan, a plurality of data elements forming a scan fragment (100) for at least a portion of the bar code (20), identifying each fragment (100) containing a portion of a reference key (104), detecting when there has been a match between a reference key (104) and the identified key fragments, determining if a complete key (194) has been constructed from the key fragments, calculating a displacement between the key fragments which constructed the complete key (194), and aligning data fragments of the bar code (20) by placing each successive data fragment in alignment with the previous data fragment offset by the amount of the displacement.
Patent CA-2365074-A1 (CA)
Inventor: WOOD JEFFREY A
IPC: E02B7/54
Filed: 2001-12-17
Abstract: A fixable-seal sluice gate has a valve vise that forces a sluice-gate valve uniformly and tightly in sealing-surface contact with a domed seal ring that is fixable conveniently and removably intermediate a sluice-gate plate and a sluice-gate wall of a sluice-gate flange that encompasses a valve side of a sluice-gate aperture. A plate locator on the valve vice sets the sluice-gate plate in predetermined sealing- contact position for select structure of the fixable-seal sluice gate. The domed seal ring is a plastic material such as Hypalon® having predetermined toughness to resist particle embedment in combination with having predetermined softness for select uses and objectives. A dome flange on one or both sides of a base of the domed seal ring is bracketed removably to optionally the sluice-gate wall or the sluice-gate plate for rigid, reliable, long-enduring and yet quick and convenient attachment and detachment of the domed seal ring.
Patent CA-2366232-A1 (CA)
Title: Diagnosis of lysosomal storage disorders using saposins and other markers
Inventor: MEIKLE PETER JOHN
IPC: C12Q1/68
Filed: 2000-03-17
Abstract: The invention provides methods of diagnosing or monitoring lysosomal storage  disorders based on detecting levels of saposins, LAMPs and/or .alpha.- glucosidase in patient sample. Elevated levels of saposins and/or LAMPs are indicative of a disorder. Elevated levels of .alpha. glucosidase are indicative of some types of lysosomal storage disorders and decreased levels  of .alpha. glucosidase are indicative of other types of lysosomal storage disorder. In some methods, the profile of elevation of different saposins, LAMPs and .alpha. glucosidase allows distinction between different types of lysosomal storage disorder.
Patent CA-2367095-A1 (CA)
Title: Device of a tool spindle
Inventor: LIND BJORN
IPC: B23B31/00
Filed: 2000-01-19
Abstract: Supply unit for a tool spindle wholly or partially equipped with a moveable pulling rod (3) axially displaceable in the spindle axle (1) for firmly attaching the tool with a fluid supply system for displacing the pulling rod (3), with a fluid supply system for cooling a rotor (22) supported on the spindle axle for driving the spindle axle, a fluid supply system for cooling the tool, and a gas supply system for blocking fluid leakage in gaps between parts that move in relation to one another. The invention is distinguished in that the supply unit includes, for one or more of the said systems, at least one sensor that senses if a malfunction exists in the fluid and/or gas supply system, and, for one or more of the said systems, an accumulator (704, 164, 243) that from indicated malfunction signals obtained from one or more sensors feeds into the system or systems complementary and replacement fluid respectively gas to the tool spindle at the same time as the sensor or sensors deactivate the driving source of the spindle.
Patent CA-2367377-A1 (CA)
Title: Wearable aerosol delivery apparatus
Inventor: GARON MARK
IPC: A61M15/00
Filed: 2000-03-14
Abstract: The present invention relates to a wearable aerosol delivery apparatus for releasing an aerosol with an active ingredient into an oral or nasal passage of a user.  The apparatus comprises a housing comprising a first and a second surface, the first surface being adapted to be disposed against a wrist of the user, the housing defining a reservoir for containing the aerosol under pressure, an aerosol release mechanism connected with the reservoir for releasing a dose of the aerosol from the reservoir when actuated, and a fastener member attached to the housing to fasten the housing onto the user's wrist, whereby the apparatus is worn by the user and effective for delivering the active ingredient into the user's passage on demand.
Patent CA-2367549-A1 (CA)
Title: Local change of an image sharpness of photographic images with masks
Inventor: KRAFT WALTER
IPC: G06T5/20
Filed: 2002-01-14
Abstract: A process for the image sharpening of a photographic image with a multitude of image elements is disclosed, wherein a correction mask for the change of the image sharpness is determined from the image data representing the image to be corrected, whereby the elements of the correction mask for the change of the image sharpness locally describe the degree of contrast change to be carried out for the individual image elements, and whereby additional information relating to the image is used for the determination of the elements in addition to information on the local contrast.
Patent CA-2368309-A1 (CA)
Title: Variantes peptidiques du marqueur tumoral muc1 et leur utilisation
Inventor: MULLER STEFAN
IPC: C07K14/705
Filed: 2000-02-17
Abstract: L'invention concerne des variantes peptidiques du marqueur tumoral MUC1 et leur utilisation dans des agents antigènes et immunogènes. L'invention concerne plus proprement dit des variantes peptidiques de l'unité de répétition du MUC1 dans le domaine VNTR (variable number of tandem repeats = nombre variable de séquences répétées en tandem).
Patent CA-2368626-A1 (CA)
Title: Preparation au cilostazol
Inventor: YAMADA KEIGO
IPC: A61K31/4709
Filed: 2000-03-21
Abstract: La présente invention concerne une préparation au cilostazol pour laquelle on incorpore une fine poudre de cilostazol dans un agent dispersant et/ou solubilisant de façon à en augmenter la dispersabilité et/ou la solubilité. L'invention concerne également un procédé permettant d'augmenter l'absorbabilité d'un médicament faiblement soluble tel que le cilostazol, même dans la partie inférieure des voies digestives. En effet, ce médicament est difficile à absorber dans la partie inférieure des voies digestives lorsqu'on utilise le procédé conventionnel. Selon l'invention, le cilostazol s'absorbe en quantité suffisante, même dans la partie inférieure des voies digestives, pour avoir une action en tant que thrombolytique, et que médicament améliorant la circulation cérébrale, ou analogue.
Patent CA-2369590-A1 (CA)
Title: Sodium/proton antiporter gene
Inventor: FUKUDA ATSUNORI
IPC: C07K14/415
Filed: 1999-12-22
Abstract: The present inventors successfully cloned the rice Na+/H+  antiporter gene. It is possible to produce salt tolerant plants by using the isolated gene, or genes with equivalent functions.
Patent CA-2370432-A1 (CA)
Title: Crop seeder
Inventor: AUDIGIE JEAN-CHARLES
IPC: A01C19/00
Filed: 2002-02-05
Abstract: The seeder comprises a dosing device (4) driven by a mechanism (10) provided with an input shaft, a pinion and a control handle which rotates with the shaft.
Patent CA-2373764-A1 (CA)
Title: Herbicidal emulsifiable concentrates
Inventor: SCHMIDT FRIEDRICH
IPC: A01N25/30
Filed: 2000-06-27
Abstract: The invention relates to a non-aqueous, emulsifiable concentrate (EC) formulation for herbicidal crop protection active compounds which consists essentially of: a) 25 to 150 g/L of at least one fluorinated herbicidal compound; b) 400 to 900 g/L of one or more herbicidal alkyl phenoxyalkanoates; c) 10 to 100 g/L of at least one non-ionic surfactant; d) 10 to 100 g/L of at least one benzene sulfonate; e) 50 to 600 g/L of one or more solvent selected from the group consisting of aliphatic or aromatic hydrocarbons, methylated plant oils and water-miscible polar aprotic organic solvents; and f) optionally, up to 5 g/L of at least one defoamer; and to the use of such an emulsifiable concentrate as a herbicide.
Patent CA-2374092-A1 (CA)
Title: Process and apparatus for the digital production of a picture
Inventor: MAIER MICHAEL
IPC: H04N1/387
Filed: 2002-03-01
Abstract: For the production of a photographic picture from an original image image (V) present in electronic form, the digital image data of the original image are recorded, especially exposed, onto a sheet type picture carrier (P) by way of a digital recording arrangement. The picture carrier is thereby located in recording position on a recording platform (10). During the positioning of the picture carrier (P) on the recording platform the picture carrier is measured with respect to size and position relative to the recording platform (10) by a photoelectric scanning device (21). A  position and size correction is carried out on the basis of the thereby obtained measurement data. In the case of a photographic recording, this correction can be carried out by a corresponding adjustment of the projection optics. Alternatively, the image data of the original image image (V) are transformed by calculation and only the transformed image data are recorded on the picture carrier (P). The transformation of the image data consists essentially of an image shift and possibly an adaptation of the image size and, if required, an image rotation. Size variations and positioning errors of the picture carrier can be captured by the measuring of the picture carrier (P) on the recording platform (10) and the correction of the position and size depending on the data determined during the measurement, and the image to be reproduced can be optimally recorded on the picture carrier within the conventional tolerances.
Patent CA-2374630-A1 (CA)
Title: Computer system control via interface surface
Inventor: LAPSTUN PAUL
IPC: G06F3/0354
Filed: 2000-05-24
Abstract: A method of enabling a user to instruct a computer system to perform an operation via an interface surface and a sensing device. The interface surfa ce includes an interface, the interface including visible graphical information  and substantially invisible coded data. When the sensing device is placed by  the user into an operative position relative to the interface surface to designate at least some of the graphical information, it senses indicating data indicative of the operation using at least some of the coded data. The graphical information designated is at least partially indicative, to the user, of the operation. The operation indicated by the indicating data is th en performed in the computer system.
Patent CA-2376023-A1 (CA)
Inventor: KILPATRICK IAN CHARLES
IPC: C07D281/10
Filed: 2000-06-16
Abstract: The present invention provides a method of treating obesity and related conditions such as bulimia, anorexia, snacking, binge eating, non insolin dependent diabetes meltitus, hyperglycaemia, stress, hyperlipidaemia, and to aid to smoking cessation comprising the administration to a mammal, particularly a human, in need thereof of a therapeutically effective amount of a compound of formula (I) in which: n=0, 1 or 2; R1 and R2 independently represent H or alkyl of 1 to 4 carbon atoms (optionally substituted by one or more halo); R3 and R4 independently represent H or alkyl of 1 to 4 carbon atoms; or together represent a group of formula =NR12 where R12 represents H, hydroxy, alkyl of 1 to 4 carbon atoms, a phenyl or alkoxy of 1 to 4 carbon atoms; each alkyl, phenyl and alkoxy being optionally substituted with one or more halo; R5 represents: (a) H, (b) alkyl of 1 to 4 carbon atoms, (c) a group of formula-COR13 in which R13 represents H, alkyl of 1 to 4 carbon atoms or phenyl, when R3 and R4 represent H or alkyl (optionally substituted with one or more halo, or (d) or a group of formula -S(O)pR14 in which p=1 or 2 and R14 is alkyl of 1 to 4 carbon atoms or phenyl, when R3 and R4 represent H or alkyl (optionally substituted with one or more halo); each alkyl and phenyl being optionally substituted with one or more halo; R6 and R7 are each H; R8 to R11 independently represent H, halo, cyano, nitro, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, alkanoyl of 1 to 4 carbon atoms, carboxy, alkanoyloxy of 1 to 4 carbon atoms, carbamoyl (optionally substituted with alkyl of 1 to 4 carbon atoms), or sulphamoyl (optionally substituted with alkyl of 1 to 4 carbon atoms); each alkyl, alkoxy, alkanoyl or alkanoyloxy optionally substituted with one or more halo; their stereoisomers; and pharmaceutically acceptable salts thereof.
Patent CA-2376574-A1 (CA)
Inventor: DAWSON MARY M
IPC: A47L25/00
Filed: 2000-02-23
Abstract: The invention includes a first dispenser for providing a first dilute concentrate of a use solution in a bottle. This bottle is then used in a portable delivery/dilution device which provides for a second level of concentration of the use solution. The bottles in which the solution is plac ed has both a vertical and horizontal lockout. The horizontal lockout is useful  in making certain the right bottles are utilized with each dispenser and the  vertical lockouts are useful in guiding the bottle upwards as the first concentration of liquid is placed in the bottle. The portable delivery/dilution system is easily portable, easily filled with water which can be easily poured from a system after use. The battery is rechargeable an d can be used in most any application where spraying is desired.
Patent CA-2381239-A1 (CA)
Title: Dibenzopyrans as glucocorticoid receptor antagonists for treatment of diabetes
Inventor: LANE BENJAMIN C
IPC: C07D311/80
Filed: 2000-09-01
Abstract: The instant invention relates to compounds of formula (I) which are useful as antagonists of the glucocorticoid receptor and for treating diabetes in a mammal. In addition, any glucocorticoid receptor antagonist(s) is useful for the treatment of diabetes.
Patent CA-2384204-A1 (CA)
Title: Method and process for validating roaming, international cellular users
Inventor: GROOTWASSINK DAVID B
IPC: H04W74/00
Filed: 2000-09-11
Abstract: A roaming user requesting access to a roamed network is not given the service until it is first validated. The roamed network queries the HLR of the user through a SCP and provides the service only if the HLR validates the user.
Patent CA-2385855-A1 (CA)
Title: Addressable valve arrays for proportional pressure or flow control
Inventor: CABUZ EUGEN I
IPC: F16K31/02
Filed: 2000-09-22
Abstract: An addressable array (11, 37) is interposed between a source pressure (Ps) and an exit pressure (Pe) chamber. The array (11, 37) comprises a plurality of valves, the total open area of which define the opening between the source pressure (Ps) and the exit pressure (Pe). Also provided is an actuator for separately actuating each valve of the array between an open and a closed condition, whereby the total number of open valves determines the flow between the source pressure and the exit pressure. The preferred valves are electrostatically actuated valves including upper and lower electrodes addressable by a conductor, and are fabricated monolithically on a substrate.