baber/WOPTO huggingface dataset:
Patent CN-100522981-C (CN)
Title: 一种雷莫拉宁的纯化方法
Inventor: BIN XU
IPC: C07G11/00
Filed: 2006-02-24
Granted: 2009-08-05
Abstract: 本发明公开了一种雷莫拉宁的纯化方法，其包括将雷莫拉宁的粗提液浓缩物与部分硅胶混合，挥干溶剂，再将得到的固体混合物置于以硅胶为填充物的柱子上端进行柱层析，其中依次用丙酮、甲醇水溶液、以及甲醇与酸水的混合物作为流动相。本发明的提纯方法步骤简单，有机溶剂使用量明显减少，并具有较高的收率和纯度。
Patent CN-100506380-C (CN)
Inventor: ZAIKU XIE
IPC: B01J27/185
Filed: 2006-08-11
Granted: 2009-07-01
Abstract: 本发明涉及一种用于裂解汽油选择性加氢的催化剂，主要解决现有技术中存在难以制备低温活性高、抗干扰能力强、容胶能力高、稳定性好并具有良好的耐游离水性能的裂解汽油选择性加氢催化剂的技术问题。本发明通过采用以载体氧化铝重量百分比计，包括：(a)0.01～0.5%的活性组分金属钯或其氧化物；(b)0.01～0.8%的选自元素周期表中IA或IIA中的至少一种元素或其氧化物；(c)0.01～20.0%的选自元素周期表中IVA或VA中的至少一种元素或其氧化物；(d)氧化铝载体；其中氧化铝载体比表面积为40～160米 2 /克，总孔容为0.3～1.2毫升/克，孔直径＜30纳米的孔容占总孔容的5～60%，孔直径30～60纳米的孔容占总孔容的20～75%，孔直径＞60纳米的孔容占总孔容的20～60%的技术方案较好地解决了该问题，可用于裂解汽油选择性加氢的工业生产中。
Patent CN-100424145-C (CN)
Inventor: XIAOXUN LIU
IPC: C08G18/48
Filed: 2006-05-15
Granted: 2008-10-08
Abstract: 一种紫外光固化水性聚氨酯丙烯酸酯涂料树脂，主要用芳香族二异氰酸酯、聚乙二醇、多羟基羧酸、三元醇、甲基丙烯酸羟乙酯(或甲基丙烯酸羟丙酯)、三乙胺等原料制成，首先将聚乙二醇滴加到芳香族二异氰酸酯中，反应得到聚氨酯预聚体I；然后把多羟基羧酸加入到聚氨酯预聚体I中，再滴加二元醇，反应得到聚氨酯预聚体II；再把加有阻聚剂的甲基丙烯酸羟乙酯(或甲基丙烯酸羟丙酯)滴加到聚氨酯预聚体II中，反应得到聚氨酯丙烯酸酯齐聚物；往齐聚物中加入三乙胺进行成盐反应，再加入水，搅拌，乳化得到紫外光固化水性聚氨酯丙烯酸酯涂料树脂，这种涂料树脂具有极佳的水溶性、良好的柔韧性、较快的光固化速度，且用水稀释后的乳液稳定性很好。
Patent CN-100412343-C (CN)
IPC: F02N99/00
Filed: 2006-04-27
Granted: 2008-08-20
Abstract: 本发明的用于控制具有LPI发动机的车辆起动性能的方法，用于缩短根据停机时间预先确定的点火准备灯的最大开启时间，也就是说，根据燃料的气化率优化地预先确定点火准备时间，从而解决点火装置准备时间过长的问题。
Patent CN-100493522-C (CN)
Inventor: ZHENHUA HUANG
IPC: A61K36/074
Filed: 2006-05-30
Granted: 2009-06-03
Abstract: 本发明属于医药技术领域，公开了一种主要由苦参素、灵芝或灵芝多糖和香菇多糖制成的药物组合物，用于肝癌、肺癌、食道癌、胃癌、鼻咽癌、直肠癌、乳腺癌等及白细胞低下的治疗，也可用于肝炎、肝硬化、乙型肝炎病毒携带者，或可作为癌症手术前用药或用于联合放、化疗中。具有协同增效作用，且稳定性好，比单用同剂量的苦参素、灵芝或灵芝多糖、香菇多糖的效果大大提高，产生了意想不到的效果。该药物组合物可与药学上可接受的辅料混合制成任何一种临床上或药学上可接受的剂型，具有广泛的应用前景。
Patent CN-100582708-C (CN)
Title: 用于将车轮装到车轮平衡试验机上的起重设备
Inventor: MARCO MATTEUCCI
IPC: G01M1/02
Filed: 2006-05-18
Granted: 2010-01-20
Abstract: 用于将车轮装到车轮平衡试验机上的起重设备，包括支撑平台，用于将至少一个车轮装到车轮平衡试验机的基本水平的平衡轴上或从平衡轴上拆除；还包括所述平台的起重设备和处于基本平行于所述平衡轴方向的所述平台的滑动装置，其特征在于该起重设备包括在工作构造中将所述车轮保持在所述平台上的可拆除装置，在该工作构造中车轮本身的旋转轴线基本上平行于所述平衡轴。
Patent CN-100590396-C (CN)
Inventor: BERNHARD THOBE
IPC: G01F23/24
Filed: 2006-07-25
Granted: 2010-02-17
Abstract: 本发明涉及一种测量装置(10)，用于确定电导率LF的导电液体在垂直方向(z方向)上的液位高度变化时通过容器(5)的流量d(V(z))。具有一个电导率测量装置，其具有至少两个在z方向上延伸的电极(30a、b)。容器(5)和/或电导率测量装置(10a)这样设计，使其可以通过至少一个取决于V(z)的参数函数f p1 (V(z))进行说明。这些参数函数的至少一个必须具有与V(z)的指数关系。本发明还涉及一种测量元件(20)以及一种用于确定总流量d(V)的方法。
Patent CN-100563469-C (CN)
Title: 一种方便即食鲜海带制品加工方法
Inventor: JIANPING XU
IPC: A23L17/60
Filed: 2007-02-09
Granted: 2009-12-02
Abstract: 本发明涉及一种方便即食鲜海带制品加工方法，属于食品加工领域。海带经过清洗、烫漂、切丝、配料、包装工序，其特点是，在配料工序和包装工序之间设有斩拌工序，将切碎的海带放入斩拌锅中斩拌成0～10毫米的长度，配料工序中各组分的重量份为海带100～200重量份，卡拉胶8～20重量份，调味剂0.7～0.8重量份，增味剂0.01～0.5重量份，氯化钠0.5～1.5重量份，木糖醇1～30重量份，异Vc钠0.05～1重量份，山梨酸0.05～1重量份，螯合剂0.1～0.5重量份。实现海产品深加工和进一步增值，克服传统食用缺陷，补充人体所需的微量元素，发挥海带对人体的保健功能。
Patent CN-100450730-C (CN)
Title: 具有欠驱动自适应机构的拟人机械手
Inventor: SHUNCHONG LI
IPC: B25J15/08
Filed: 2007-06-07
Granted: 2009-01-14
Abstract: 本发明涉及一种具有欠驱动自适应机构的拟人机械手，属于机械技术领域。本发明是对加拿大多伦多大学TBM拟人机械手的改进，包括手指结构中的弹性杆机构和指间的差动机构。手指结构部分引进了长度可变的弹性杆机构，实现了单一手指对任意物体表面的自适应包络，克服了现有技术中手指灵活度不够的缺点；而差动机构部分，通过齿轮-齿条将驱动电机输出的旋转运动转换为直线运动，主动的齿条一端连接有一个齿轮，齿轮同时与两条被动齿条啮合，两条被动齿条分别与手指连接，通过被动齿条的前后运动带动手指完成抓握动作，从而实现手指间的欠驱动，即一个电机驱动两个手指运动，本发明改善了手指间的力分配问题，减小了功耗，利于机械手的小型化。
Patent CN-100531671-C (CN)
Inventor: XIANGDONG LIU
IPC: A61B5/103
Filed: 2007-11-06
Granted: 2009-08-26
Abstract: 本发明公开了一种双色激光扫描式医用静脉显示装置。红外激光器发出的红外激光经二相色性反射镜反射，可见光激光器发出的可见激光经全反射镜反射后再透过二相色性反射镜与所述红外激光组成共线光路，光束被行扫描镜、场扫描镜依次反射并扫描到待扫描皮肤区域，待扫描皮肤区域上方设有红外探测器，红外激光器、可见光激光器、行扫描镜、场扫描镜、红外探测器均由控制单元控制。本发明可用于临床诊疗中帮助医护人员快速准确找到病患者静脉血管的准确位置，尤其适用于婴幼儿、肥胖型及深肤色病患者。本发明精度高、可实时显示、使用方便，能有效提高静脉血管定位的速度和精度，减轻诸如静脉注射等医疗环节医患双方的可能负担。
Patent CN-100561985-C (CN)
Inventor: LI KONG
IPC: H04W28/10
Filed: 2007-09-27
Granted: 2009-11-18
Abstract: 本发明公开了一种基于业务优先级的流量控制方法及其系统，其中，该方法包括：参数配置步骤，配置所述流量控制系统在业务流量周期内允许接入的系统业务流量总数、各类业务的业务权重和业务优先级、各业务优先级对应的业务流量比率；负荷控制步骤，在业务请求接入时，判断在所述业务流量周期内当前已接入业务的业务流量总数是否小于所述系统业务流量总数，如果是，则获取所述业务的业务权重、业务优先级和所述业务优先级对应的业务流量比率，并根据获取的参数对所述业务进行流量控制。采用本发明有效地保证了负荷/流量控制效果，防止突发业务对系统的影响，使得低优先级业务突增时，不会影响高优先级业务的接入。
Patent CN-100594242-C (CN)
Title: 一种铁水脱硫渣稀渣剂
Inventor: DEGANG OUYANG
IPC: C21C1/02
Filed: 2008-07-28
Granted: 2010-03-17
Abstract: 本发明公开了一种改善铁水脱硫渣流动性能的铁水脱硫渣稀渣剂，由以下重量百分比的原料组成：萤石粉45～55%，锂辉石矿粉22～28%，工业纯碱15-20%，硼砂3～5%和氧化铁皮粉2～4%。其中，萤石粉中CaF 2 的含量≥85%，粒度≤0.178mm；锂辉石矿粉是由天然矿细磨制成，粒度≤0.150mm，其主要化学成分的重量百分比含量为：Li 2 O，0.8～1.5%；SiO 2 ，71～76%；Al 2 O 3 ，18～20%。氧化铁皮粉为轧钢氧化铁皮球磨制成，粒度≤0.178mm。工业纯碱中Na 2 CO 3 的含量≥98%。硼砂中Na 2 B 4 O 7 ·10H 2 O的含量≥95%。本发明以萤石粉、锂辉石矿粉、工业纯碱为主要原材料，能有效改善铁水脱硫渣流动性能，适合于渣量大、碱度高、粘度大、熔点高的脱硫渣的助熔，原材料成本低。
Patent CN-100591830-C (CN)
Title: 洗衣装置
Inventor: MYUNG-SIK KIM
IPC: D06F37/00
Filed: 2008-09-19
Granted: 2010-02-24
Abstract: 本发明公开了一种洗衣装置，包含有如下几个部分：壳体；设置于上述壳体的内部，并用于容纳衣物的滚筒；结合于上述壳体的前面的边角部分的外廓面板；结合于上述壳体的前面中心部，并形成有用于将衣物投放到上述滚筒的投放口的前面板；结合于上述外廓面板和前面板之间的位置，并构成上述壳体的前面的一部分的辅助面板。本发明中的洗衣装置，将可更加提高洗衣装置的耐久性。
Patent FR-68497-E (FR)
Inventor: WEXLER EMMANUEL
IPC: B29C65/48
Filed: 1955-07-13
Granted: 1958-04-30
Abstract: 802,292. Making containers and closures therefor. BASSAN, M. R. May 1, 1956 [May 12, 1955 ; July 13, 1955], No. 13408/56. Class 87(2). [Also in Group XVII] A process for the manufacture of containers having walls made of thin flexible sheets of thermo-weldable plastic material comprises injection moulding, at at least one of the extremities of the body, a reinforcing rib of the same plastic material onto those edges that are to be joined, the material being injected at a temperature sufficient to produce fusion of the plastic material constituting the thin walls. In Fig. 2, the mould comprises a dished outer part 33 having a gate 34, and a piston-shaped inner part 35 having an annular rubber gasket 36 for co-operating with a rim 37 on the part 33. In operation, a tube 38 of thermoplastic sheet material is stretched over the rubber gasket 36 and a thermoplastic end sheet 39 is placed on the inner part 35. The outer part 33 is then placed in position and a plastified thermoplastic material is injected through the gate 34 to form ribs uniting the tube 38 to the sheet 39. Strengthening ribs may at the same time be moulded onto the sheet 39. The container may be closed by flattening it at its upper end as in Fig. 4 and inserting the flattened end into an injection moulding machine for applying thereto a reinforcing strip 6 complete with handle 11, screwed spout 7 and screw cap 9. Fig. 6 is a cross-section through a mould for this purpose. It comprises two parts 20, 20a having cavities for making the parts 6, 7, 9 and 11, the spout-cavity 22 containing a core for forming the passage of the spout 7. The flattened top edges of the container walls 27 are inserted from below into the cavity 21, the base of the cavity 21 being sealed by a rubber gasket 29. An injection gate 25 is made in the mould part 21. Polyvinyl chloride and polythene are suitable plastics. Several different containers (see Group XVII) are described. The stiffening ribs may be reinforced by metal wires, fiber threads or other material of high tensile strength.
Patent MX-4026-E (MX)
Inventor: GROSZ ROLL FRIEDRICH
IPC: F28D7/10
Filed: 1978-03-31
Abstract: The heat exchanger is constructed with a plurality of fittings which are disposed in the flow passage. Each fitting is constructed of at least two groups of webs with the webs of each group disposed in spaced parallel relation and in angular relation to the axis of the flow passage. Also, each group of webs is disposed in crossing relation to the webs of the other group. The ratio of web width (b) to diameter (d) of the flow passage is in the range of from 0.08 to 0.5 while the ratio of web spacing (m) to the diameter (d) is in the range of from 0.38 to 0.9. The fittings permit improved heat transfer with reduced pressure losses and a relatively small total area.
Patent MX-5203-E (MX)
Inventor: EIZEMBER RICHARD FRANK
IPC: C07C67/00
Filed: 1978-07-17
Abstract: Hydrochloric acid in either 20-38% concentration or gaseous form is effective is removing nitrosamines from a number of dinitroaniline herbicides.
Patent PT-1176383-E (PT)
Inventor: KAATZ MICHAEL
IPC: F28F25/12
Filed: 2000-06-28
Abstract: The cooling tower has a cooling chamber (1) and water injection from horizontal spray jets (13). There is a first air entry (11) below the water injection and a second one (19) from the side above it. The second air entry runs through a tube (16) with two or more stages, projecting into the cooling chamber. The stages diminish successively in cross section.
Patent PT-1171173-E (PT)
Inventor: DIJK BASTIAAN PHILIP VAN
IPC: A61F2/82
Filed: 2000-04-13
Abstract: The invention relates to a stent manufactured from an alloy which contains at least 60% by weight, based on the weight of the alloy, of one or more metals selected from the group of gold, platinum, palladium and silver, silver being used only in combination with gold, platinum and/or palladium, and the alloy having a yield point of at least 200 N/mm<SUP>2 </SUP>and an elongation at break of at least 8%.
Patent PT-1224205-E (PT)
Inventor: PAUL BARRACLOUGH
IPC: A61P25/14
Filed: 2000-09-29
Abstract: The invention discloses the use of sapogenin derivatives in the treatment of cognitive dysfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed.
Patent PT-1386934-E (PT)
Title: Diagnostic agents for pancreatic exocrine function
Inventor: LIMITED TOKYO GAS COMPANY
IPC: A61K49/06
Filed: 1999-09-24
Abstract: The present invention provides a <13>C-labeled oligosaccharide or polysaccharide or a salt thereof excluding U-<13>C-maltose, <13>C-starch, 1-<13>C-maltotetraose and 1-<13>C-amylose; a derivative of the <13>C-labeled oligosaccharide or polysaccharide or salt thereof; a <13>C-labeled inclusion complex or a salt thereof, which comprises a cyclodextrin or a modified derivative thereof as a host molecule; a <13>C- or <14>C-labeled fluorescein ester compound or a salt thereof; and a diagnostic agents for pancreatic exocrine function comprising these compounds <13>C- or <14>C-labeled.
Patent PT-1509253-E (PT)
Title: Chimeric cd154
Inventor: CANTWELL MARK J
IPC: A61K38/00
Filed: 2003-05-23
Abstract: The present invention provides for an isolated polynucleotide sequence encoding a chimeric CD154, comprising a first nucleotide sequence encoding an extracellular subdomain of non-human CD154, preferably murine CD154, that replaces a cleavage site of human CD154, and a second nucleotide sequence encoding an extracellular subdomain of human CD154 that binds to a human CD154 receptor. The present invention also provides for the chimeric CD154 that is encoded by the above-described polynucleotide sequence, an expression vector and a genetic vector comprising the polynucleotide sequence, a host cell comprising the expression vector or the genetic vector, a process for producing the chimeric CD154, and methods for utilizing the expression vectors and genetic constructs containing the chimeric CD154 polynucleotide sequences.
Patent PT-1560578-E (PT)
Inventor: YANNIS TSOUDEROS
IPC: A61P1/04
Filed: 2003-11-04
Abstract: The use of distrontium 2-(N,N-di(carboxymethyl)amino)-3-cyano-4-carboxymethyl thiophene-5-carboxylate (I) (strontium ranelate) and its hydrates in medicines for the treatment of gastro-duodenal pain.
Patent PT-1428820-E (PT)
Inventor: SCHWARTZ JEAN-CHARLES
IPC: C07D295/096
Filed: 1999-07-29
Abstract: The present invention provides new non-imidazole alkylamine derivatives, and their use for preparing medicaments acting as ligands at the H 3 -receptors of histamine.
Patent PT-1467091-E (PT)
Title: Floating water current turbine with counter rotating coaxial rotors
Inventor: RIKSEN SVEIN
IPC: F03D9/00
Filed: 2002-07-08
Abstract: The present invention comprises a rotating member (400) designed for rotation actuated by currents in the body of water so as to function as energy supplier in a generator unit located in a body of water. The rotating member, as illustrated in Figure 7, is built up around a shaft (405) which is mounted (preferably at right angles) on a hub on the generator shaft. The rotating member according to one embodiment of the invention comprises an inner end piece (407) mounted on the shaft (405) at the attachment of the shaft to the hub, a tip (406) mounted at the outer end of the shaft, and a plurality of member sections (410) rotatably mounted on the shaft (405) between the end piece (407) and the tip (406). <??>Each member section (410) is individually selectively pivotal and adjustable about said shaft, in order that the rotating member as such can assume the optimal pitch in relation to the water current. <IMAGE> <IMAGE>
Patent PT-1671747-E (PT)
Title: Support for sanding apparatus
Inventor: COE ANDREW
IPC: B24B23/06
Filed: 2004-12-15
Abstract: A support stand (2) for a sanding apparatus having a housing, a motor, and a sanding belt of abrasive material adapted to be driven around a plurality of rollers by means of the motor is disclosed. The support stand (2) comprises a body portion (6) having recesses (10, 14, 18, 22) for engaging corresponding parts of the sanding apparatus to expose the sanding belt of the sanding apparatus, and a control knob (26) mounted to the body portion (6) to be accessible by a user's hand when the sanding apparatus is supported on the support stand (2). The support stand also has a wheel (36) having a friction belt (38) for engaging a belt speed adjustment knob of the sanding apparatus to enable adjustment of the speed of the sanding belt of the sanding apparatus in response to rotation of the control knob (26) in order to control the rate of removal of material by the sander.
Patent PT-1644336-E (PT)
Title: Nitrogen-containing heteroaryl compounds and their use in increasing endogeneous erythropoietin
Inventor: FLIPPIN LEE A
IPC: C07D217/26
Filed: 2004-06-04
Abstract: The present invention relates to compounds I suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin  in vitro  and  in vivo .
Patent PT-1663320-E (PT)
Title: Targeting of tumor vasculature using radiolabelled antibody l19 against fibronectin ed-b
Inventor: HILGER CHRISTOPH-STEPHAN
IPC: C07K16/46
Filed: 2004-09-01
Abstract: A specific binding member that binds human ED-B, wherein the specific binding member is labelled with an isotope selected from the group consisting of 76Br, 77Br, 123I, 124I, 131I and 211At and comprises an antigen-binding site that comprises an antibody VH domain and an antibody VL domain, wherein the antibody VH domain is selected from the group consisting of the L19 VH domain, and a VH domain comprising a VH CDR1, a VH CDR2 and a VH CDR3, wherein the VH CDR3 is the L19 VH CDR3 of SEQ ID NO.3, the VH CDR1 is optionally L19 VH CDR1 of SEQ ID NO.1, and the VH CDR2 is optionally L19 VH CDR2 of SEQ ID NO.2; and wherein the antibody VL domain is optionally selected from the group consisting of the L19 VL domain, and a VL domain comprising a VL CDR1, a VL CDR2 and a VL CDR3, wherein the VL CDR3 is the L19 VL CDR3of SEQ ID NO.6, the VL CDR1 is optionally L19 VL CDR1 of SEQ ID NO.4, and the VL CDR2 is optionally L19 VL CDR2 of SEQ ID NO.5; the L19 VH domain and L19 VL domain sequences being disclosed in Pini et al. (1998) J. Biol.Chem.273: 21769-21776; wherein the specific binding member comprises a mini-immunoglobulin comprising said antibody VH domain and antibody VL domain fused to eS2-CH4 and dimerized or comprises a whole IgG1 antibody molecule; also methods and uses employing such a specific binding member.
Patent PT-1658362-E (PT)
Title: Liquid dish cleaning compositions
Inventor: SZEWCZYK GREGORY
IPC: C11D1/22
Filed: 2004-08-27
Abstract: A liquid dish cleaning composition with desirable cleansing properties comprising two C<SUB>8-18 </SUB>ethoxylated alkyl ether sulfate surfactants, two anionic surfactant, an amine oxide surfactant, and water.
Patent PT-1619932-E (PT)
Title: Insulating element
Inventor: SOULARD DOMINIQUE
IPC: F24H1/00
Filed: 2005-07-06
Abstract: The insulating unit (5) has a central recess (13) that permits to reduce the weight of the insulating unit greater than ten percent. Notches (10, 11) rotate the insulating unit with respect to an adjacent insulating unit so as to provide an angular shift between successive insulating units and block translation of a conductor wire of a steatitic resistor. The unit (11) cooperates with the unit (10) of an adjacent insulating unit. An independent claim is also included for a heating unit constituted by assembling of a set of insulting units.
Patent PT-1769731-E (PT)
Title: Vaginal speculum arrangement
Inventor: BALAS KONSTANTINOS
IPC: A61B1/303
Filed: 2005-09-29
Abstract: The present invention relates to a vaginal speculum embodying an applicator for the uniform delivery of a standardized dose of a liquid diagnostic marker onto the woman's lower genital tract. The applicator comprises of a marker container and a mechanism for transferring a desirable quantity of its content to an injection probe for dispensing the marker onto the tissue surface. The probe may be a nozzle generating a desirable injection pattern, depending on the location of the tissues to be examined. The probe may be affixed to an extension rod, which may be mechanically coupled with the speculum blades. Optical, electronic imaging means, illumination means and treatment tools may be mounted onto the extension rod, which rod may be detachably attached to mechanical positioning systems or to imaging devices used in colposcopy. The disclosed speculum arrangement may be used as a tool for diagnostic and screening examinations and for the treatment of cervical and vaginal neoplasias.
Patent PT-1711558-E (PT)
Title: Syndiotatic polypropylene composition comprising a thermoplastic elastomer
Inventor: KARSTEN PETRUS
IPC: C08L23/12
Filed: 2005-01-28
Abstract: Polymer composition comprising a thermoplastic elastomer including styrene and isoprene and/or vinylisoprene units (SI) and a syndiotactic polypropylene (s-PP).
Patent PT-1721162-E (PT)
Title: Method of assessing rheumatoid arthritis by measuring anti-ccp and serum amyloid a
Inventor: JOHANN KARL DR
IPC: G01N33/564
Filed: 2005-02-23
Abstract: The present invention relates to a method aiding in the assessment of rheumatoid arthritis. The method especially is used in assessing the absence or presence of rheumatoid arthritis in vitro. It can be best practiced by analyzing biochemical markers, comprising measuring in a sample the concentration of anti-CCP and serum amyloid A and correlating the concentrations determined to the absence or presence of rheumatoid arthritis. To further improve the assessment of RA in a method of this invention the level of one or more additional marker may be determined together with anti-CCP and serum amyloid A and be correlated to the absence or presence of RA. The invention also relates to the use of a marker panel comprising anti-CCP and serum amyloid A in the diagnosis of rheumatoid arthritis and it teaches a kit for performing the method of the invention.
Patent PT-1910175-E (PT)
Title: Packaging with sealing lid and method for filling the package.
Inventor: HOWES ANDREW
IPC: B65D8/04
Filed: 2005-07-21
Abstract: A packaging for a pharmaceutical product comprising a body portion (10) having an opening (24) for dispensing the pharmaceutical product; and a lid portion (12) adapted to seal the opening by means of a projection (20) adapted to be received in the opening of the body, wherein the projection is adapted to form a substantially airtight bore seal with the opening.
Patent PT-1685840-E (PT)
Title: Use of tetrahydrofolates for modulating the homocysteine level
Inventor: ULMANN MARTIN
IPC: A61P9/00
Filed: 1998-06-05
Abstract: Use of tetrahydrofolates in natural stereoisomeric form for production of a pharmaceutical preparation to influence homocysteine levels, to treat and prevent cardiovascular disorders and to prevent neural tube deficiencies is new. The compounds are applied when a methylene tetrahydrofolate reductase deficiency or thermolabile methylene tetrahydrofolate reductase exists. Tetrahydrofolates in the natural (S) form assist remethylation of homocysteine, and therefore act as homocysteine level modulators. They are of use in prevention and treatment of conditions in which there is deficiency of cystathione beta -synthase and/or 5,10-methylene tetrahydrofolate reductases enzymes. These conditions include cardiovascular disorders, notably arteriosclerosis, and for neural tube deficiencies. The compounds can be used either alone, or in combination with other bioactives, notably vitamins, and especially those of the B-group, B6 and B12, which have synergistic action.
Patent PT-1752471-E (PT)
Title: Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
Inventor: RUEKER FLORIAN
IPC: C07K16/00
Filed: 2006-01-05
Abstract: An immunoglobulin variable domain or part thereof, comprising at least one structural loop region of a variable domain of the immunoglobulin heavy or light chain, said at least one structural loop region comprising at least one modification to provide a non-CDR binding site binding to an epitope of an antigen, which unmodified structural loop region does not bind to said epitope. as well as nucleic acid encoding said immunoglobulin and pharmaceutical preparations.
Patent PT-1744202-E (PT)
Title: Progressive spectacle lens
Inventor: GUILLOUX CYRIL
IPC: G02C7/06
Filed: 2006-04-21
Abstract: The lens has a complex surface having a cylinder value normalized to the addition of less than 0.8 in a circle of radius 20mm with respect to the center of lens. The rebound in the sphere quantity normalized to the addition on the circle is less than 0.04, and the progression length defined between fitting cross and a point on the meridian at which the mean sphere reaches 85% of progression of the addition, is 14mm or less. Independent claims are also included for the following: (1) method for correcting vision of presbyopic subject; and (2) method for fitting ophthalmic lens in visual equipment.
Patent PT-1976483-E (PT)
Title: Pharmaceutical device for the administration of substances to patients
Inventor: COSTA SAMODH DE
IPC: A61K35/08
Filed: 2006-11-21
Abstract: Biological materials such as vaccines can be stabilized in certain glassy materials soluble in water. It has been proposed to form these glassy materials as a powder suspended in a non-aqueous liquid for injection into a patient. This method is complicated by the need to find suitable compatible liquids and to stop the glassy particles from congregating in liquid. These problems have been obviated by supporting the glassy material on a porous membrane remote from the eluant. When the biological material requires administration, the eluant can be passed across the membrane dissolving the glass and causing the substance to be carried by the liquid into the patient.
Patent PT-1942754-E (PT)
Title: Electrical smoking system
Inventor: RIPLEY ROBERT L
IPC: A24F40/485
Filed: 2006-10-02
Abstract: A tobacco mass is heated to a temperature of about 150° to about 220° C. to release flavorful tobacco volatiles, which are entrained in air passing through the tobacco mass, and condensed to form an inhalable aerosol. The tobacco mass may have a rotationally symmetric shape, with at least part of its surface in heat transfer relationship with a heater. The heater may be an external shell, an internal rod, or a plate. A shell can enclose the heater and tobacco mass and define a preheating chamber for inflowing air. A mouthpiece, with or without a filter, may be arranged in fluid communication with the tobacco mass to direct the aerosol from the heating system.