baber/WOPTO huggingface dataset:
Patent WO-2021097072-A1 (WO)
Title: Tamper evident blister packaging
Inventor: COLLIER PAUL
IPC: B65D83/04
Filed: 2020-11-12
Abstract: A tamper evident package comprises a blister assembly defining at least one cavity, the opening of the at least one cavity being at least partially closed by a membrane. A sleeve housing the blister assembly is provided, the sleeve having a top side and a bottom side, the bottom side having a contact window that is aligned with the cavity. In addition, a package integrity feature is applied to the bottom side and covers the contact window. The package integrity feature is further applied to the membrane covering the cavity through the contact window.
Patent WO-2021097339-A1 (WO)
Title: Crystalline forms of c-c chemokine receptor type 4 antagonist and uses thereof
Inventor: ARNOLD DAVID
IPC: C07D487/04
Filed: 2020-11-13
Abstract: Crystalline forms of a C-C chemokine receptor type 4 (CCR4) antagonist, oral dosage forms of same and methods of using and preparing same, are provided.
Patent WO-2021108528-A1 (WO)
Title: Dérivés de carbazole polymorphes et leurs utilisations
Inventor: CASTRO ALFREDO C
IPC: A61K31/5365
Filed: 2020-11-25
Abstract: La présente invention concerne des formes de base libre et de sel, et des compositions et des procédés associés, utiles pour traiter diverses affections dans lesquelles le récepteur d'hydrocarbure aryle (AHR) est impliqué, par administration de petites molécules thérapeutiques qui agissent en tant qu'inhibiteurs de l'AHR.
Patent WO-2021119023-A1 (WO)
Inventor: SHERBENOU DANIEL
IPC: A61K31/505
Filed: 2020-12-08
Abstract: Multiple myeloma (MM) combination therapies based on protein translation inhibitors, immunomodulators, and bromodomain extra-terminal inhibitors. Methods are provided for treating multiple myeloma in a subject, including administering a therapeutically effective amount of at least one protein translation inhibitor and a therapeutically effective amount of at least one immunomodulatory drug (IMiD), administering a therapeutically effective amount of at least one protein translation inhibitor and a therapeutically effective amount of at least one BET inhibitor, and/or administering a therapeutically effective amount of at least one IMiD and a therapeutically effective amount of at least one BET inhibitor.
Patent WO-2021119443-A1 (WO)
Inventor: ZHOU XIAOYUAN
IPC: C07F7/08
Filed: 2020-12-11
Abstract: Described herein are methods for making alkenyl disiloxanes, comprising combining an alkenyl halosilane with a  bis -hydrido terminated alkyl disiloxane and adding the mixture to water, an acidic aqueous solution, or a basic aqueous solution. The ratio of the alkenyl halosilane to the  bis -hydrido terminated alkyl disiloxane is about 1:10 to about 10:1. The alkenyl halosilane and  bis -hydrido terminated alkyl disiloxane are mixed at about 20 °C to about 45 °C. In an example, no organic solvent is present. The reaction product is separated and washed with saturated NaHCO 3  solution (e.g., sodium bicarbonate).
Patent WO-2021126948-A1 (WO)
Title: Seamless edge application handover
Inventor: SEED DALE
IPC: H04W36/00
Filed: 2020-12-16
Abstract: An edge application handover client in a user equipment may use application client information, such as type service, provider, location, context, and sendee requirements, to assist seamless edge application handovers of application clients between edge application servers. For example, a handover client may use context information to determine an anticipated route of the user equipment, and thereby determine a next, edge application server for a handoff. The handover client may weigh the needs of multiple application clients m selecting servers for handovers. The handover client may issue requests to servers requesting assistance in handover operations, and may issue subscription requests to servers, and further may determine the success of handovers by monitoring application state synchronization or migration between edge application handover servers.
Patent WO-2021138562-A1 (WO)
Title: Compositions comprising bacterial species and methods related thereto
Inventor: PAPKOFF JACKIE
IPC: C12N1/20
Filed: 2020-12-31
Abstract: The disclosure relates generally to bacterial strains of the genus Collinsella, e.g., Collinsella ASMB bacterial strains, and compositions, e.g, pharmaceutical compositions, comprising such strains. The disclosure further relates to methods of using such strains and compositions for preventing or treating a disorder, e.g, a cancer, when administered to a subject in need thereof.
Patent WO-2022159067-A1 (WO)
Inventor: ROMERO MIKE
IPC: E03D9/00
Filed: 2021-01-19
Abstract: Un ensemble borne de toilettes de véhicule qui comprend une enceinte avec une pluralité de parois qui coopèrent pour définir un intérieur de toilettes, une porte d'entrée positionnée sur l'une de la pluralité de parois, et un ensemble tour positionné sur l'une de la pluralité de parois. Un évidement de désinfection est défini dans une surface avant de l'ensemble tour, et l'évidement de désinfection comprend un accès au désinfectant pour les mains à l'intérieur de celui-ci.
Patent WO-2021154757-A1 (WO)
Title: Nickel-containing catalyst composition having enhanced acidity for steam reforming processes
Inventor: ALSOLAMI BANDAR
IPC: B01J23/00
Filed: 2021-01-26
Abstract: Modified red mud catalyst compositions, methods for production, and methods of use in steam reforming, the composition comprising: red mud material produced from an alumina extraction process from bauxite ore; and nickel oxide, the nickel oxide present at between about 5 wt.% to about 40 wt.% of the modified red mud catalyst composition.
Patent WO-2021154818-A1 (WO)
Title: Monitoring system for care protocols
Inventor: LECAMWASAM HARISH
IPC: G16H40/60
Filed: 2021-01-27
Abstract: A monitoring system for care protocols, comprising sensors connected to electronic devices to input data from a patient, where sensors measure critical values from a patient; an interface for receiving data and allowing users to write and change process control in real time; a processor connected to the interface to receive input parameters, wherein the processor calculates output values based on the input parameters compared to the critical value to determine whether the output values are outside acceptable range; means for setting critical values, ranges of critical value, and alarm points when the critical values are outside of the range; where the interface receives critical patient parameters and the interface includes a manual input and a machine input from one or more sensors; and wherein the system calculates and monitors critical steps or values for a patient and enables the output values for monitoring or display, in real time.
Patent WO-2021158597-A1 (WO)
Title: Despiking reservoir properties
Inventor: ASHRAF MUHAMMAD
IPC: G01V99/00
Filed: 2021-02-03
Abstract: A computer system receives multiple datapoints of a geomechanical property of a hydrocarbon reservoir modeled by a three-dimensional (3D) grid. Each datapoint corresponds to a respective grid cell of the 3D grid. Each grid cell of the 3D grid is represented by 3D coordinates. For each grid cell of the 3D grid, the computer system generates a data component of the geomechanical property based on the 3D coordinates of the grid cell. The computer system adds the data component to a datapoint corresponding to the grid cell to provide an augmented set of datapoints. The computer system transforms the augmented set of datapoints into a Gaussian distribution using Gaussian approximation. The computer system simulates the geomechanical property of the hydrocarbon reservoir based on the Gaussian distribution using sequential Gaussian simulation. A display device of the computer system generates a graphical representation of the geomechanical property of the hydrocarbon reservoir based on the sequential Gaussian simulation.
Patent WO-2021178107-A1 (WO)
Inventor: COX KEVIN
IPC: H02G1/12
Filed: 2021-02-08
Abstract: An electric spinning pliers apparatus includes a housing, a plier head coupled to a rotatable shaft, and a head-operating handle. The housing may have a wire sleeve stripper, an iris door, one or more controls, and an indicator light. The electric spinning pliers apparatus utilizes the wire sleeve stripper to cut an outer sleeve of a group of wires, exposing individual wires. Each individual wire may be stripped by the iris door, while the plier head may grasp and rotate, via a motor, each of the individual wires into a single unit. The plier head may then twist a wire nut on the twisted wires.
Patent WO-2021173359-A1 (WO)
Inventor: GASIUNAS GIEDRIUS
IPC: C12N15/82
Filed: 2021-02-11
Abstract: Compositions and methods are provided for genome modification of a target sequence in the genome of a cell, using a novel Cas endonuclease. The methods and compositions employ a guide polynucleotide/endonuclease system to provide an effective system for modifying or altering target sequences within the genome of a cell or organism. Also provided are novel effectors and endonuclease systems and elements comprising such systems, such as guide polynucleotide/endonuclease systems comprising an endonuclease. Compositions and methods are also provided for guide polynucleotide/endonuclease systems comprising at least one endonuclease, optionally covalently or non-covalently linked to, or assembled with, at least one additional protein subunit, and for compositions and methods for direct delivery of endonucleases as ribonucleotide proteins.
Patent WO-2021167854-A1 (WO)
Title: Smart-learning and knowledge retrieval system
Inventor: VENKATASUBRAMANYAM GOPALAKRISHNAN
IPC: G06N20/00
Filed: 2021-02-15
Abstract: A computer-implemented method and a smart-learning and knowledge retrieval system (SLKRS) are provided for imparting adaptive and personalized e-learning based on continually artificially learned unique characteristics of a knowledge seeker. The SLKRS ingests data in multiple formats from multiple sources, merges the data into a knowledge base based on computed strengths of terms in the sources, and assimilates the merged data to generate experiences. In response to a query received from the knowledge seeker, the SLKRS retrieves and sends in an immersive format one of the generated experiences or an experience created based on an artificially intelligent understanding of the received query. The SLKRS receives feedback from the knowledge seeker and computes a score based on the feedback and the query to artificially learn unique characteristics of the knowledge seeker. The SLKRS generates interventions and improved experiences for the knowledge seeker based on the computed score.
Patent WO-2021168371-A1 (WO)
Inventor: BROWNE ADAM
IPC: E04B1/24
Filed: 2021-02-19
Abstract: L'invention concerne un appareil pour supporter un ou plusieurs tuyaux. L'appareil comprend une première tour, une seconde tour, et chaque tour comprend quatre colonnes verticales, et un premier ensemble de poutres horizontales. Chaque poutre est conçue pour s'étendre entre et relier deux des colonnes verticales par l'intermédiaire de colliers de liaison à moment biaxial. Les tours sont alignées pour supporter un premier tuyau sur des poutres à partir des deux tours le long d'un axe de support de tuyau primaire, et aucune des colonnes de la première tour n'est reliée à une colonne de la seconde tour par un collier de liaison à moment biaxial.
Patent WO-2021168444-A1 (WO)
Title: Analyte sensing device
Inventor: LIM SUNG H
IPC: C01B32/182
Filed: 2021-02-22
Abstract: A sensing device for detecting analytes within a package or container is disclosed. The sensing device may include a substrate, one or more electrodes, and a sensor array disposed on the substrate. The sensor array may include a plurality of carbon-based sensors coupled to the one or more electrodes. Each sensor may be configured to react with a unique group of analytes in response to an electromagnetic signal received from an external device. In some instances, a first sensor may be functionalized with a first material configured to detect the presence of each analyte of a first group of analytes, and a second sensor may be functionalized with a second material configured to detect the presence of each analyte of a second group of analytes. The second group of analytes may be a subset of the first group of analytes, and the second material may be different than the first material.
Patent WO-2021247132-A1 (WO)
Inventor: YANG CONNIE QIN
IPC: G06F11/34
Filed: 2021-04-05
Abstract: Systems and methods directed to generating a predicted quality metric are provided. Telemetry data may be received from a from a first group of devices executing first software. A quality metric for the first software may be generated based on the first telemetry data. Telemetry data from a second group of devices may be received, where the second group of devices is different from the first group of devices. Covariates impacting the quality metric based on features included in the first telemetry data and the second telemetry data may be identified, and a coarsened exact matching process may be performed utilizing the identified covariates to generate a predicted quality metric for the first software based on the second group of devices.
Patent WO-2021211391-A1 (WO)
Title: Continuous utility pole health monitoring based on finite element analysis and operational modal analysis using das
Inventor: DING YANGMIN
IPC: G08B21/18
Filed: 2021-04-11
Abstract: Aspects of the present disclosure describe distributed fiber optic sensing (DFOS) systems, methods, and structures that advantageously enable and/or facilitate the continuous monitoring and identification of damaged utility poles by employing a DFOS distributed acoustic sensing (DAS) methodology in conjunction with a finite element analysis and operational modal analysis. Of particular advantage and in further contrast to the prior art, systems, methods, and structures according to aspects of the present disclosure utilize existing optical fiber supported/suspended by the utility poles as a sensing medium for the DFOS / DAS operation.
Patent WO-2021216350-A1 (WO)
Title: Notification et commande de pompe à fluide basées sur une rétroaction contrôlée
Inventor: GRAY GEORGE
IPC: A61M5/142
Filed: 2021-04-15
Abstract: Un système de distribution de fluide selon la présente invention comprend une pompe à fluide et un système de gestion de fluide. Le système de gestion de fluide reçoit une entrée indiquant un fluide (tel qu'un médicament, une thérapie, etc.) d'un type particulier à administrer à un receveur. Le système de gestion de fluide mappe le type particulier du fluide à un ensemble de paramètres de patient devant être surveillés pendant l'administration du fluide au receveur. Pendant l'administration du médicament particulier au receveur, le système de gestion de fluide surveille la rétroaction du receveur pour chacun du ou des paramètres dans l'ensemble. Sur la base de la rétroaction, le système de gestion de fluide commande l'administration du fluide au receveur.
Patent WO-2021216503-A1 (WO)
Inventor: KMIEC ERIC
IPC: C12N15/113
Filed: 2021-04-20
Abstract: The disclosure provides a polynucleotide comprising: a first DNA sequence encoding a guide RNA (gRNA), wherein the gRNA comprises a DNA-binding domain and a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated endonuclease protein-binding domain, and the DNA-binding domain is complementary to a target sequence in an NRF2 gene; and a first promoter that is operably linked to the DNA sequence. The disclosure also provides vectors (e.g. AAV vectors), recombinant AAV (rAAV) and pharmaceutical compositions comprising the polynucleotides described herein. The disclosure further provides a method of treating cancer in a subject, the method comprising administering to the subject a therapeutically effective amount of a polynucleotide, vector, rAAV or pharmaceutical composition as described herein to the subject.
Patent WO-2021225976-A1 (WO)
Title: Safe use of bile acids and their salts as enhancers for nasal delivery of pharmaceuticals
Inventor: ZHANG JACK
IPC: C07K14/50
Filed: 2021-05-03
Abstract: The present disclosure introduces safe and effective pharmaceutical formulations for intranasal delivery. Specifically, the present disclosure introduces the safe clinical use of bile acids or salts thereof as an enhancer to exhibit improved bioavailability and tissue tolerance. In several embodiments, pharmaceutical formulations including bile acids or salts thereof are provided. In several embodiments, the formulations are suitable and/or configured for the intranasal (IN) delivery, methods of manufacturing such formulations, and methods of treating patients using such formulations. The pharmaceutical formulations comprising bile acids, salts of bile acids, and/or combinations thereof. In several embodiments, bile acids, salts of bile acids, and/or combinations thereof are configured for use as absorption enhancers.
Patent WO-2021226461-A1 (WO)
Title: Generation of optimized nucleotide sequences
Inventor: TRAN KHANG
IPC: G16B25/00
Filed: 2021-05-07
Abstract: A method for generated an optimized nucleotide sequence is provided. The method comprises at least normalizing a codon usage table and selection of codons for a given amino acid sequence based on the usage frequency of the codons in the normalized codon usage table. The method may comprise generating a list of a plurality of optimized nucleotide sequences encoding the amino acid sequence, filtering the list of optimized nucleotide sequences, synthesizing one or more optimized nucleotide sequence, and/or administering one or more synthesized optimized nucleotide sequence.
Patent WO-2021231540-A1 (WO)
Title: Bladder for article of footwear
Inventor: ELDER ZACHARY
IPC: A43B13/12
Filed: 2021-05-12
Abstract: A bladder for an article of footwear includes a plate, a first tensile layer disposed adjacent to a first side of the plate, and a second tensile layer disposed on an opposite side of the plate from the first tensile layer, the second tensile layer joined to the first tensile layer through the plate by a plurality of inner bonds. The bladder additionally includes a first barrier layer disposed adjacent to the first tensile layer and joined to the first tensile layer by a plurality of first outer bonds to form a first chamber, one or more of the first outer bonds interposed between adjacent ones of the inner bonds.
Patent WO-2021242969-A1 (WO)
Title: Procédé et système de changement de pas d'article
Inventor: ZIEGLER KELLY
IPC: B65B65/02
Filed: 2021-05-27
Abstract: L'invention concerne un procédé de changement de pas d'article. Le procédé peut consister à recevoir une série d'articles disposés selon un premier pas, mettre en prise les articles de la série d'articles séquentiellement avec une roue de préhension, déplacer les articles le long d'un trajet de déplacement avec la roue de préhension et déplacer les articles l'un par rapport à l'autre, du premier pas à un second pas pendant le déplacement des articles le long du trajet de déplacement avec la roue de préhension.
Patent WO-2021243091-A1 (WO)
Title: System for test and measurement instrumentation data collection and exchange
Inventor: KUHLMAN III FREDERICK
IPC: G08C17/02
Filed: 2021-05-27
Abstract: A method of capturing instrument data using a communications device includes recognizing an action performed by a user on the communication device, one of either transmitting or receiving a trigger message between the communications device and at least one instrument, storing instrument data in a memory on the at least one instrument, and transmitting the instrument data and user information to a network. A test system includes a test and measurement device having at least one communications link, a memory, and a processor configured to execute instructions that cause the processor to receive a message through the communications link, save instrument data into the memory, and transmit the instrument data to a remote location; and a communications device having at least one communications link, a memory, and a processor configured to execute instructions that cause the processor to recognize an action performed by a user, send the message to the test and measurement device, store associated information including user information, and transmit the user information to the remote location.
Patent WO-2021243134-A1 (WO)
Title: Footwear airbag with flexible electronic interconnect
Inventor: SCHNEIDER SUMMER L
IPC: A43B13/20
Filed: 2021-05-28
Abstract: Articles of footwear, systems, and methods include an upper portion, a lower portion, secured to the upper portion, the lower portion including an out-sole and an airbag assembly. The airbag assembly includes a first sheet and a second sheet forming a seal therebetween around a perimeter of the first and second sheets. The airbag assembly further includes an electronic assembly, comprising a circuit board and electrical conductors disposed on the circuit board, wherein an internal portion of the electronic assembly is disposed between the first and second sheets and within the seal formed therebetween and an external portion of the electronic assembly is disposed outside of the seal.
Patent WO-2021257566-A1 (WO)
Title: Synthesis of anthracitic networks and ambient superconductors
Inventor: BISHOP MATTHEW
IPC: C01B32/05
Filed: 2021-06-15
Abstract: Several variations of synthetic carbon materials are disclosed. The materials can assume a variety of properties, including high electrical conductivity. The materials also can have favorable structural and mechanical properties. They can form gas impenetrable barriers, form insulating structures, and can have unique optical properties.
Patent WO-2022011144-A1 (WO)
Title: Pipeline systems and methods for use in data analytics platforms
Inventor: COLCORD AARON
IPC: G06F7/00
Filed: 2021-07-08
Abstract: A data analytics system including an append-only first data store accessible to multiple clients and a second data store is disclosed. The data analytics system can be configurable to, in response to receiving first instructions from a first target system of a first client, the first target system separate from the data analytics system, create a first pipeline between the append-only first data store and the second data store. The first pipeline can be configured according to the first instructions to generate a client- specific data object and store the client- specific data object in the second data store. The data analytics system can be configurable to tear down the first pipeline upon completion of storing the client-specific data object in the second data store.
Patent WO-2022011257-A1 (WO)
Title: Systems and methods for temperature control in rf ablation systems
Inventor: OH SEIL
IPC: A61B18/12
Filed: 2021-07-09
Abstract: The present disclosure provides systems and methods for controlling temperature in a radiofrequency (RF) ablation system. A temperature control system includes a subtractor circuit configured to calculate a temperature error as a difference between a target temperature and a measured temperature at a tip of a cannula, and a proportional-integral-derivative (PID) controller coupled to the subtractor circuit and configured to apply an RF voltage to the tip of the cannula, the PID controller configured to determine the RF voltage based on the temperature error and a proportional coefficient, an integral coefficient, and a derivative coefficient of the PID controller. The temperature control system further includes a PID coefficient controller coupled to the PID controller, the PID coefficient controller configured to dynamically adjust the proportional, integral, and derivative coefficients of the PID controller during operation of the RF ablation system.