Patent DE-102011009854-A1 (DE)
Title: Sensor device for measuring analytes, comprises a housing having a measuring space, in which a biological component is arranged as a transducer, where the biological component is partially or completely covered by a planar area
Inventor: KOTTKAMP EIKE
IPC: G01N33/50
Filed: 2011-02-01
Abstract: The sensor device comprises a housing (12) having a measuring space, in which a biological component (22) is arranged as a transducer, where the biological component is partially or completely covered by a planar area, and is connected with the housing formed from a plastic injection molding for the analyte to measure a permeable covering agent (28). The covering agent: fixes the biological component in its position into the measuring space; limits an undesired movement of the biological component into the measuring space; and adjoins at the biological component in an area-wise manner. The sensor device comprises a housing (12) having a measuring space, in which a biological component (22) is arranged as a transducer, where the biological component is partially or completely covered by a planar area, and is connected with the housing formed from a plastic injection molding for the analyte to measure a permeable covering agent (28). The covering agent: fixes the biological component in its position into the measuring space; limits an undesired movement of the biological component into the measuring space; adjoins at the biological component in an area-wise manner; and/or is formed in a cap-like manner with a curved surface. The housing of an injection molded part is made of plastic. The covering agent: is overmolded in connection regions (30) for a connection with the housing with the plastic; is designed as a permeable network for the analyte to be measured or as permeable membrane for the analytes to be measured; is flexibly formed; and is springily stored at the housing in such a way that the covering agent is carried along at a size growth of the biological component. The sensor device has a lighting organ with which the biological component is partially illuminable and/or an optical control device with which the biological component is supervisable from an outside of the sensor device. The control device comprises an optical acquisition organ such as a lens or a camera, which is arranged in an inner side of the measuring space or in a wall limiting the measuring space. The optical acquisition organ is connected with a spacer with which light signals or electric signals originating from the optical acquisition organ are externally guided from the measuring space. The spacer is an optical waveguide with which the light signals are externally guidable from the measuring space. The optical acquisition organ is a permeable observation element for the light made of glasses, which are integrated in an external wall of the housing, by which the biological component is observable and/or optical detectable. The biological component is arranged on an inner side of the external wall. The observation element on a back side of the biological component is integrated into the external wall so that the back side of the biological component is observable from an outer side of the observation element. The measuring space of a first locked state incorporates a gaseous or liquid medium in which it is media-tightly closed, where the gaseous or liquid medium obtains the biological component, holds in a defined reference state, and/or is converted into a second state, in which the measuring space is unlocked and escapes from the measuring space into the gaseous or liquid medium. Supply- and/or derivatives externally lead to the measuring space, in which a locked state is closed by a closure unit for transferring the measuring space in the unlocked state of a removable and/or corrodible closure unit. A biological component is assigned to an unit for stimulating an electrode and/or an actuator such as a mechanical energy of an actuator transferred to the biological component, which is operatively connected with a transducer adjoining into the measuring space against the biological component dependent on reactions of the component due to an interaction with the analyte, electromagnetic or optical signals, where the transducer is optionally secured together with further electronic parts into the measuring space to the limiting wall. The transducer is optionally arranged with the further electronic parts on a stabilizing support material such as glasses, ceramic or silicon, where the support material is secured to the measuring space limiting wall. The support material is flexibly formed. The housing comprises a flow channel (16), by which the analyte inflows/outflows from the outside into the housing. The measuring space: is connected to the flow channel so that the analyte pours into the measuring space; and is immediately arranged in the flow channel, by which the analyte flows into the housing. The housing comprises a main flow channel. The biological component is spaced apart from the main flow channel in a chamber closed by a branch line connected with the measuring space. The sensor device further comprises a valve arranged into the housing, and/or a pumping device arranged in or on the housing. A control- and/or regulating device is arranged in or at the housing with which the valve and/or the pumping device is controllable and/or variable.