baber/WOPTO huggingface dataset:
Patent DO-P2007000012-A (DO)
Title: Derivados nuevos de urea ciclica, su preparacion y su utilizacion farmaceutica como inhibidores de cinasas
Inventor: HALLEY S A
Filed: 2007-01-12
Abstract: La invencion se refiere a nuevos productos de formula (I): en la que X1 Y X2 representan: ya sea el uno al hidrogeno y el otro al alquilo; ya sea el uno a -OCF3 0 -SCF3 y el otro a NH-CO-alquil-R3; ya sea X1 Y X2 forman con el radical fenil al que estan unidos un radical di-hidroindol opcionalmente sustituido; R representa piridilo o pirimidinilo sustituidos por NR1R2, representando R, hidrogeno o alquilo, y representando R2 alquilo opcionalmente sustituido, cicloalquilo, heterocicloalquilo, fenilo, pirimidinilo, piridilo, y CO-R3 con R3 que representa principalmente amina, alcoxi, heterocicloalquilo, arilo, ariloxi y heteroarilo; estando todos estos radicales opcionalmente sustituidos; y sus sales.
Patent DO-P2010000217-A (DO)
Title: Compuestos de 3h-[1,2,3] triazolo[4,5-d]pirimidina, su uso como inhibidores de mtor quinasa y p13 y sus sintesis
Inventor: AYRAL-KALOUSTIAN SEMIRAMIS
IPC: C07D487/04
Filed: 2010-07-14
Abstract: La invención se refiere a compuestos de 3H-[1 ,2,3]triazolo[4,5- d]pirimidina de Fórmula 1: o a una sal farmacéuticamente aceptable de los mismos, en la que las variables constituyentes son como se definen en el presente documento, a composiciones que comprenden los compuestos y a procedimientos para fabricar y usar los compuestos.
Patent DO-P2018000209-A (DO)
Title: Constructos de alfavirus vivo atenuado y métodos y usos de los mismos
Inventor: JILL ANN LIVENGOOD
IPC: C12N15/86
Filed: 2018-09-28
Abstract: La presente invención se refiere a alfavirus vivos atenuados que son incapaces de replicarse en células de mosquitos y de transmisión por mosquitos vectores. Otras modalidades se refieren a métodos para generar alfavirus vivos atenuados, constructos de los mismos y usos de estos alfavirus vivos atenuados en composiciones inmunogénicas. Otras modalidades se refieren a composiciones farmacéuticas que incluyen los alfavirus vivos atenuados y métodos para manufacturar estos virus vivos atenuados. Todavía otras modalidades se refieren a los usos de estas composiciones en kits para aplicaciones portátiles tales como vacunas contra la infección por alfavirus y métodos de los mismos.
Patent DO-P2020000009-A (DO)
Title: Implante dental
Inventor: FELIX ANDREAS MERTIN
IPC: A61C8/00
Filed: 2020-01-15
Abstract: La presente invención se refiere a un implante dental (1) que comprende un núcleo (2); una rosca (3); una primera región (12) y una segunda región (13), y un eje central (11); la superficie del núcleo (2) definiendo un ángulo (6) y un ángulo (7), y la superficie de rosca (3) definiendo un ángulo (8) y un ángulo (9). El diámetro (14) del núcleo (2) disminuye a una tasa en la primera región (12) hacia la extremidad apical (16), de modo que el ángulo (6) sea mayor que el ángulo (8) y el diámetro (14) del núcleo (2) disminuye a una tasa en la segunda región (13) hacia la extremidad apical (16), de manera que el ángulo (7) sea igual al ángulo (9). Además, la presente invención prevé un implante (1) que comprende al menos una cámara helicoidal (5), dicha cámara helicoidal (5) posee una profundidad y una longitud (5.1).
Patent GB-189709822-A (GB)
Title: Improvements in Drawers or Pants.
Inventor: ROBERTS MERCEDES ANNETTE
Filed: 1897-04-17
Granted: 1897-06-19
Abstract: 9822. Roberts, M. A. April 17. Drawers a n d pants, especially those for children, are provided with loops b at their lower ends to fit under the feet and prevent t h e drawers from rising up. The loops are preferably knitted in one with the drawers.
Patent GB-189710515-A (GB)
Title: Improvements in and relating to Means for Preventing the Refilling of Bottles.
Inventor: SIEGEL FREDERICK LUDWIG
Filed: 1897-04-27
Granted: 1897-07-10
Abstract: 10,515. Siegel, F. L. April 27. Stoppers; refilling, preventing.- Relates to means for preventing the refilling of bottles. The neck of the bottle is bulged to form two shoulders a, a<1>, between which is secured the cylindrical valve casing B. The casing is made i two sections b, b<1>, which are held in position by the cork rings C. The lower end of the casing is formed as a seating d for the spherical float valve D, which is normally held in position by the ball E. An inverted cup F is fixed between ribs d<1> on the casing, to receive and guide the balls E, D when the bottle is inverted. A shield G is fixed above the casing, to prevent tampering with the valve. The balls D, E permit the contents of the vessel to be poured out, but prevent refilling, the valve D acting as a float valve when the vessel is inverted, and being held on its seat by the ball E when the vessel is upright. A heavy ball is placed within the vessel to aid in unseating the valve when emptying the vessel. In a modification, the two parts of the casing are screwed together, and a stop-plate is provided within the casing to limit the movement of the valve.
Patent GB-189713925-A (GB)
Title: Improvements in or relating to Pumps Suitable for Inflating Pneumatic Tyres.
Inventor: GOODWIN HAROLD RICHARD
Filed: 1897-06-05
Granted: 1898-02-05
Abstract: 13,925. Goodwin, H. R. June 5. Inflating pneumatic tyres. A pump for inflating pneumatic tyres is provided at the bottom with an extension 7 for resting it upon the ground. A slot is left at the side of the extension to permit the fixed or removable flexible tube 6 to be extended in line with the pump when it is being attached to the tyre valve aud to be curved up at the side when the end of the pump is placed upon the ground. A foot-piece 12 is fitted to the extension 7, and is hinged as shown, or made in one with the part 7, or detachably fitted to it. The extension 7 is fixed to the pump barrel 1 or to the h o l l o w piston - rod according to the make of the pump.
Patent GB-189720490-A (GB)
Title: Improvements in and in the Manufacture of Certain Parts of Cycle Pedals.
Inventor: WHITEHOUSE ALFRED
Filed: 1897-09-07
Granted: 1898-05-14
Abstract: 20,490. Whitehouse, A. Sept. 7. Pedals.-The spindle a is grooved at a' to receive the balls e, and the bearing is completed by the socket d, cupped at d<1> and screwing into the cavity c<1> of the flush-ended plate c<2>. When the ball bearing is adjusted, the socket d is locked by the ring f. The inner end of the spindle has a collar a<3> which fits into a recess c<6> in the plate c<3>. The end plates c<2>, c<3> are formed integral with the halfside plates c<7>, c<8> which are chamfered at their overlapping ends and secured by bolts or rivets c<11>. In one modification, the socket d has a plain outer surface, and is screwed internally to engage a corresponding thread on the end of the barrel b which also receives the locking - ring. Fig. 14 shows a modification, in which the adjusting-socket d is provided with a milled flange d<4>, and the locking-device consists of a plate k screwed into a recess in the end plate c<2>.
Patent GB-189720998-A (GB)
Title: Improvements in and connected with Calculating Apparatus.
Inventor: SCHABADT ABRAHAM
Filed: 1897-09-13
Granted: 1898-09-03
Abstract: 20,998. S c h a b a d t, A. Sept. 13. Calculating - apparatus.-A series of endless bands c are provided with projections c' to be engaged by the finger, which run in slots d'. On either side of the slot the casing is marked with scales 1 to 9 and 9 to 1 for addition and subtraction respectively, but where the 5 should fall on one side a gap o is cut to show the graduations on the band underneath. The bands are marked 0 to 9 three times over, and whenever the band moves so as to change its indication from 9 to 0 in adding or 0 to 9 in subtracting, one of three pins g strikes a lever f, which, acting on the sliding rod h<1> or h or its equivalent, throws forward the slide e<1> or e over the next band of higher denomination. This indicates that 1 must be added or subtracted on the next band. For example, to add 7 and 8, the finger is placed opposite 7 on the addition scale at the side of the slot d<1> of the units band, and the projection c is forced back to the bottom of the slot. 7 will then appear in the gap o. The process is then rapeated with 8 and the units band will then show 5 in the gap o, while the slide e<1> will have been thrown forward. In pushing this slide back the finger is made to engage the projection c' below it and 1 is added to the tens band. By altering the numbers on the bands &c. the apparatus may be adapted for compound addition &c. in various coinage and weights.
Patent GB-189730477-A (GB)
Title: Improvements in Machines or Apparatus for Making Sanitary Pipe Traps with Curved Arms.
Inventor: GREEN THOMAS STANLEY
Filed: 1897-12-24
Granted: 1898-10-29
Abstract: 30,477. Green, T. S., and Wragg, S. Dec. 24. Moulding drain traps.-Clay is placed in half moulds G, which are forced together about a core constructed of a vertical portion A, fixed to the table B, and a curved arm C built up of a number of curved segments. The inner ends of the segments are retained in place by a plain ring E supported by a forked lever N, and dovetail projections at the outer ends interlock with recesses in an internal ring D. One of the segments is made with parallel sides to facilitate detachment from the moulded trap. The halves of the mould carry spring stop plates I which yield in the event of excessive pressure, and allow the surplus material to escape.
Patent GB-189730817-A (GB)
Title: Improvements in and relating to the Construction of Grain Elevators or Silos.
Inventor: JOHNSON ERNEST V
Filed: 1897-12-30
Granted: 1898-06-04
Abstract: 30,817. Johnson, E. V. Dec. 30. Grain silos.-Relates to the construction of the bins forming a grain silo or elevator. The bins are built of tiles of special form arranged between layers of steel beams which are placed at intervals of about six feet throughout the height of the silo. The said beams B are preferably I-shaped in crosssection, and are secured together by plates C of the shape shown at the corners of the bins. The beams are also tied together by bars G, G secured by nuts in coupling-pieces H which are provided with flanges which engage with the flanges of the beams B. The beams are further tied together by vertical rods F, F arranged at the corners and at the centres of the sides of the bins. The tiles D are formed with recesses for the said tie-rods F and for the purpose of forming ventilation passages in the sides of the bins ; for the same reason holes b<4> b' are punched through the web of the beams B to correspond with the passages through the liles. The tiles D are formed with interlocking edges as shown in the section, Fig. 4. The central row of tiles D<1> is formed with recesses along each edge as shown, and the row of tiles D<2> next the beams B is formed with recesses to fit the flanges of the said beams.
Patent GB-189730899-A (GB)
Title: Improvements in Centrifugal Separators.
Inventor: BERRIGAN JOHN JOSEPH
Filed: 1897-12-31
Granted: 1898-02-05
Abstract: 30,899. Berrigan, J. J. Dec. 31. Cream separators. -Improvements on the invention described in Specification No. 2837, A.D. 1889. The nest of conical plates fitted into the drum is divided up into sections by discs and rings d, d<1>. The Figure shows two arrangements.
Patent GB-189801204-A (GB)
Title: New or Improved Means or Devices for Connecting Together India-rubber or other Overshoes, for the purposes of Preventing them being Exchanged or Mispaired.
Inventor: HAHN AMALIE
Filed: 1898-01-15
Granted: 1898-05-07
Abstract: 1204. Hahn, A. Jan. 15. Fastening in pairs. - Overshoes are provided with fastenings to secure them in pairs to prevent accidental mispairing when left in a cloakroom &c. Fig. 3 shows a snap fastening similar to a glove fastener, one part being attached to the side of each shoe. In Figs. 4 and 5, a stud on one part has a projecting pin a' which can be passed through a slot b<1> in the other part and slightly rotated to fasten the pair. In Figs. 7 and 8, the stud a' has a head which engages a slot b<2> in the other part.
Patent GB-189805660-A (GB)
Title: Improvements in and connected with the Drain Holes and Gratings of Sinks, Drains, and Analogous Articles.
Inventor: HYDE GEORGE
Filed: 1898-03-08
Granted: 1898-12-23
Abstract: 5660. Hyde, G. March 8. Gratings for sink &c. outlets. The grating c is made with depending catches k which engage bayonetjoint fashion with undercut grooves i in a short flanged tube b which forms the outlet. In a modification, the grooves i are formed in the material of the sink &c.
Patent GB-189808758-A (GB)
Title: Improved Connections in Sleeve and Cuff Links.
Inventor: ELLIOT HENDERSON MCGILL
Filed: 1898-04-15
Granted: 1898-10-15
Abstract: 8758. Elliot, H. McG. April 15. Sleeve - Links. - The buttons B, C are connected by a spring hook A. The hook A is attached to one button B, and preferably has a swivel a<1> in the link.
Patent GB-189809806-A (GB)
Title: Improvements in the Manufacture of Metal Plates and other Articles usually Formed by Rolling.
Inventor: GOLDING JOHN FRENCH
Filed: 1898-04-28
Granted: 1899-02-04
Abstract: 9806. Golding, J. F. April 28. Casting.-Metal is run from a ladle G into a mould comprising two parts A, B, which are hinged together by a resilient metal plate D at the bottom and are heated by flame passing through cavities a<1>, b<1> in their walls. After the metal is poured into the moulds the two parts are brought together by toggle mechanism F, and the metal is forced into a sheet ; it is allowed to remain in the mould till it has cooled to a cherry red heat, at which temperature the atmosphere does not oxidize it excessively. Several moulds may be mounted on a revolving hydraulic table. Figured plates and other articles usually made by rolling may be produced in the apparatus, particularly plates for making the expanded metal described in Specification No. 3692, A.D. 1896.
Patent GB-189813546-A (GB)
Title: Improvements in Pneumatic Tyres.
Inventor: WELCH CHARLES KINGSTON
Filed: 1898-06-17
Granted: 1899-04-22
Abstract: 13,546. Welch, C. K. June 17. Tyres, pneumatic.- The inextensible jacket A, preferably of the form described in Specification No. 13,391, A.D. 1893, has an outer cover a formed from a thin sheet of unvulcanized or slightly-vulcanized india-rubber. The cover a may be formed as a tread-piece, or the tread may be thickened by several strips. The rubber strip is specially applicable to double-tube racing tyres, but it may be applied to other tyres.
Patent GB-189814867-A (GB)
Title: Improvements in Clips for Stretching Wire Mattresses.
Inventor: BROWN HENRY
Filed: 1898-07-06
Granted: 1899-07-06
Abstract: 14,867. Brown, H. July 6. Mattresses.-Clips A fixed to the end rail of the mattress frame by screws B have holes through which pass bolts C engaging the adjustable end bar D to which the spring surface is fixed. The spring surface can be made to extend to the full size of the frame.
Patent GB-189817204-A (GB)
Title: Improvements in Apparatus for Precipitating the Solid Particles of the Top-gases of a Blast-furnace from out of the Clear Water.
Inventor: ZSCHOCKE GOTTFRIED
Filed: 1898-08-10
Granted: 1899-08-10
Abstract: 17,204. Zschocke, G. Aug. 10. Fumes, treating.-Relates to means for separating the solid matter from water used for washing the gases from a blast furnace. The water from the wash tower A passes through a valve n into a sediment chamber b, whence it passes through a filter H into a chamber a, from which it may run off through pipes c to the trough h<1>. The circular valve n is pivoted on the upper circular part b<1> of the chamber b, and may be closed by turning the handle m. While the valve n is closed the water runs into the space B. The water in the chamber a may be run off through a valve d and pipe f into the trough h, and the matter in the chamber b may be discharged by opening the door g. The filter H may be of any suitable form, such as a sheet of felt between two perforated plates.
Patent GB-189818238-A (GB)
Title: Improvements in Wheel Building Machines for Bicycle or other Light Wheels.
Inventor: BATEY JOHN
Filed: 1898-08-25
Granted: 1899-08-12
Abstract: 18,238. Batey, J. Aug. 25. Drawings to Specification. Nuts, screwing into place.-Spoke nipples for light wheels, built by a special machine, are screwed on by a tool having a split chuck, carried by a brace, which is placed over the nipple and rests against the rim. The chuck is rotated from a handle by bevel gear. As the nipple is screwed up it is grasped more and more firmly by the serrated jaws of the chuck till it presses against the rim.
Patent GB-189822768-A (GB)
Title: Improvements in Methods of, and Apparatus for, Increasing the Volume of Sounds from Telephonic or Phonographic Instruments, and Transmitting such Sounds to Distances.
Inventor: SHORT HORACE LENOARD
Filed: 1898-10-29
Granted: 1899-09-23
Abstract: 22,768. Short, H. L. Oct. 29. Instruments, phonographic, operated by keyboard. -Relates to methods of increasing the volume of sounds, for the construction of musical instruments and other purposes. The principle involved consists in operating some form of valve so as to vary the passage of compressed air, steam, &c. in accordance with the vibratory motion of a diaphragm &c. acted upon by a phonograph cylinder or disc &c. Several modifications of the instrument are described, embodying various shaped valves and arrangements of the valve rods. The principle of sound magnifying is applied to a phonographic musical instrument in which rings of vibration are recorded on a phonographic cylinder 1, Fig. 18, several rings for notes of different quality being arranged for each note of a scale. Contact-styles 16 are arranged on valves 15 around the cylinder corresponding in number to the rings to each note. The sets of styles can be thrown into and out of gear by cam rods 18 as desired. The compressed air, after passing through the valves, is conveyed by channels 4 to an annular chamber leading to a sound trumpet. The supply of air to the valves is controlled from a keyboard provided with the necessary stops.
Patent GB-189822838-A (GB)
Title: Improvements in Driving Belts.
Inventor: LOECHERT CARL
Filed: 1898-10-31
Granted: 1898-12-10
Abstract: 22,838. L ÷ c - hert, C. Oct. 31. Belts and bands. -Wire ropes are riveted along the edges at the back of a driving-belt.
Patent GB-189901393-A (GB)
Title: Improvements in Urinals for Invalids Use.
Inventor: BAXTER JOHN EDWARD JOSEPH
IPC: A61G9/00
Filed: 1899-01-20
Granted: 1899-11-11
Abstract: 1393. Baxter, J. E. J., and Taffs, A. B. V. Jan. 20. Bed - pans. - To prevent spilling, the neck is made with an inward extension b. The pan is emptied through an opening closed by a plug c.
Patent GB-189903284-A (GB)
Title: Improvements in Heel-attaching Machines.
Inventor: RAYMOND FREEBORN FAIRFIELD
Filed: 1899-02-14
Granted: 1899-09-23
Abstract: 3284. Lake, H. H., [Raymond, F. F.]. Feb. 14. Heels; nailing.-Relates to a machine for (1) attaching a heel to a boot or shoe, and (2) spanking on a top-lift. As shown in Figs. 1 and 2, the frame of the machine consists of two side portions united by a central portion a<3> in which the shaft B is journalled. On this central portion is secured a boss S on which rotates a hexagonal hub carrying six jacks. The hub is locked in one of the required positions by one of the pins P, taking into a notch in the boss. By pressing on the lever p<5> the pin is removed, whereupon the hub can be rotated to bring another jack into the operative position. The jacks have stems screwed through nuts o<10> for their adjustment as regards height, and each is carried by a plate adjusted between guide-bars o<4> by screws o<12>, o<13>. The shoe is by these means accurately centered under the heel-attaching devices. The heel is attached and the top-lift spanked on by a reciprocating crosshead C, which is actuated by cranks on the shaft B. On a shaft m journalled in the crosshead is mounted a device D having six arms arranged alternately to hold a heel and a top-lift. Any other number of arms may equally well be used. As shown in Fig. 9, the loaded heel is held by springs e<14>, e<15>, secured to side pieces e<4>. When the crosshead moves downwards, the drivers force the nails through the sole to attach the heel, the nails being usually left projecting to receive the top-lift. The-top lift is held by the device shown in Fig. 6, which is similar to that described in Specification No. 5554, A.D. 1885, or by that shown in Fig. 7. After a heel has been attached, the device D is automatically rotated to bring the spanking-device into the operative position. Spring devices are described for centering the shoe to receive the heel. Fig. 16 shows one arrangement, in which the plates w, w<1> are pushed inwards by springs within the supporting-brackets w<6>. The plates are withdrawn by means of a treadle w<11> through the gear shown. The machine is driven by a pulley N loosely mounted on the shaft B and provided with a half clutch n. The other half n' is keyed on the shaft, and is moved longitudinally in one direction by a spring and in the other by a lever n<2>. A cam n<6> acting on a latch n' stops the machine after the shaft has made two revolutions and a heel has been attached and its top-lift spanked. In place of starting the machine by means of the treadle it may be started by the rotation of the hub carrying the jacks. On the side of the hub is secured a disc carrying six cams which through a rod actuate the latch n'.
Patent GB-189915988-A (GB)
Title: Improvements in the Quick Removal to a Distance of Town Refuse and in its Conversion into Manure.
Inventor: SEFTON-JONES HERBERT
Filed: 1899-08-04
Granted: 1900-07-14
Abstract: 15,988. Sefton-Jones, H., [Soc. Anon. des Engrais Complets]. Aug. 4. Manures; refuse, treating. - Collected refuse is tipped from the carts into large pits A, and is forked on to a conveyer consisting of an endless belt running on rollers 5, 6 and passing around end drums. The conveyer is placed in a tunnel which is covered by removable hatches 8. The material is prevented from falling off the conveyer to the bottom of the tunnel by bands 9 fixed a little above the conveyer. The conveyer delivers the refuse to an elevator formed of bands 14, connected together by rivets or other means, and provided with sheet-iron paddles 15 working between two fixed side pieces 16. The shaft of the lower drum is carried by two pivoted arms, so as to keep the belt taut. The refuse is delivered to stone or like crushers, from which it is lifted by a second similar elevator to the trucks &c., for conveying the broken and mixed refuse to the fields for use as manure.
Patent GB-189921639-A (GB)
Title: Improvements relating to Automatic Brakes for Railway and other similar Vehicles.
Inventor: PASS ERNEST DE
Filed: 1899-10-30
Granted: 1899-12-09
Abstract: 21,639. Pass, E. de, [Soc. des Freins Automatiques "Stop"]. Oct. 30. Brakes.-The buffer rods c, d on each vehicle are connected to a lever e, which is pivoted at f and is connected by a rope g to the brake block i. The bunching up of the carriages due to the slowing down of the locomotive causes the brakes to be automatically supplied. The upper ends of the rods e may be connected by a cord to enable the brakes to be applied by hand power from one end of the train, and each rod is provided with a spring k for taking off its brake immediately the carriages open out again.
Patent GB-189924007-A (GB)
Title: Improvements in Dobbies Employed in Looms for Weaving.
Inventor: BOULAYE BERNARD GALBOIS
Filed: 1899-12-02
Granted: 1900-10-06
Abstract: 24,007. Boulaye, B. G. Dec. 2. Loom pattern lags and pegs.-In dobby lattices the lags a are provided with pegs b, which are mounted upon a rod d in such a manner that they can be turned down out of action without being removed from the lag, and are held in either position by springs e.