baber/WOPTO huggingface dataset:
Patent CA-2369457-A1 (CA)
Inventor: GARST MICHAEL E
IPC: A61K38/00
Filed: 2000-04-04
Abstract: A method of treating a disorder in an eye, for example, an aqueous deficient dry eye state, phacoanaphylactic endophthalmitis, or uveitis, is provided. The method generally includes administering a therapeutically effective amount of a certain cyclosporin A derivative topically to the affected eye. The derivative may be administered as a solution, suspension or ointment in a pharmaceutically acceptable excipient.
Patent CA-2373441-A1 (CA)
Title: Hard, scratch-resistant coatings for substrates
Inventor: KRISKO ANNETTE
IPC: C23C14/34
Filed: 1999-08-05
Abstract: The transparent, hard, scratch-resistant, amorphous, easily washed coating on a transparent substrate, together with a method for its preparation. A substrate such as glass is introduced into a magnetron sputtering chamber, silicon is sputtered in an atmosphere of nitrogen and a hydrocarbon gas to produce on the substrate a film containing a carbide and a nitride of silicon. The film has a thickness in the range of about 30.ANG. to about 500.ANG., and its surface exhibits a contact angle with water below about 25°. The protective coating may be applied directly to a transparent substrate such as glass, or may be applied as a protective coating over an optical film stack carried by the substrate.  If desired, a glass substrate may be coated on one side with the optical film stack and on the reverse side with the protective coating.
Patent CA-2374899-A1 (CA)
Inventor: ENGLE EARLE W
IPC: A47K13/30
Filed: 2002-03-07
Abstract: A toilet includes a toilet bowl having a rim bounding a mouth. An attached toilet seat confronts the rim and an attached odor collector is capable of being activated moving air from the toilet bowl through the mouth and deodorizing the air. Shield structure between the rim and the toilet seat inhibits air from transferring between the toilet seat and the rim and channels air from the toilet bowl to the odor collector. A sensor is capable of sensing objects and activating the odor collector in response thereto.
Patent CA-2378913-A1 (CA)
Inventor: FARR STEPHEN J
IPC: A24F40/42
Filed: 2000-07-12
Abstract: A system is disclosed which makes it possible for a patient to be delivered gradually reduced amounts of nicotine over time thereby allowing the patient to be gradually weaned off of dependence on nicotine and quit smoking. The system is comprised of a means for aerosolizing a formulation and containers of formulation. The formulation is comprised of nicotine in a pharmaceutically acceptable carrier. Preferably, a plurality of containers are produced wherein the concentration of nicotine in the different containers oR different groups of containers is reduced. The patient uses containers with the highest concentration initially and gradually moves towards using containers with lower and lower concentrations of nicotine until the patient's dependence on nicotine is eliminated.
Patent CA-2383254-A1 (CA)
Inventor: NAPIER MARY A
IPC: A61K35/76
Filed: 2000-03-30
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent CA-2386189-A1 (CA)
Inventor: SANDS ARTHUR T
IPC: G01N33/50
Filed: 2000-10-02
Abstract: The nucleotide and amino acid sequences of several novel human G protein coupled receptors are described.
Patent CA-2387135-A1 (CA)
Title: Polymorphic forms of sertraline hydrochloride
Inventor: SCHWARZENBACH FRANZ
IPC: A61P25/22
Filed: 2000-10-23
Abstract: A crystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug. Furthermore, different crystalline forms of sertraline hydrochloride alcohol solvates, crystalline forms of sertraline hydrochloride hydrates, referred to hereinafter as polymorphic form CSC1, a process for the preparation of the amorphous form of sertraline hydrochloride, and different processes for the preparation of polymorphic forms I, II, V, and T1 are disclosed.
Patent CA-2387280-A1 (CA)
Inventor: PERRIN DIDIER
IPC: C02F1/32
Filed: 2002-05-23
Abstract: A cleaning system for a UV disinfection module having a pair of headers with  a multiplicity of lamps extending therebetween including a cleaning plate havi ng a multiplicity of openings therein, the openings having lamp wipers and arrang ed to substantially coincide with positions of the lamps to permit movement of the  plate between the headers, a rotatable screw extending between the headers and through the  plate, a motor operatively connected to rotate the screw, a screw adapter fixed to th e cleaning plate at a rotatable screw opening in the plate and including a substantially cylindrical tube having opposed openings, one of the openings being aligned with the rotatabl e screw opening and a thread nut connected to each of the opposed openings, each opposed opening having a threaded central bore sized to threadingly engage threads on the rotatable screw,  whereby rotation of the screw moves the cleaning plate between the headers.   -18-
Patent CA-2387396-A1 (CA)
Title: No-rub finishing compositions
Inventor: MATTON GEORGE
IPC: C08J3/09
Filed: 2000-10-27
Abstract: A self-leveling finishing composition capable of providing chemically resistant low profile coatings is described. The finishing composition comprises thermoplastic resin solids and thermosetting resin solids in a weight ratio of about 0.5:1 to about 11:1 and a solvent composition comprising a solvent capable of dissolving the thermoplastic resin solids component and a solvent miscible co-solvent capable of dissolving the thermosetting resin solids. The finishing composition is applied and dried to a dry-to-touch surface which is thereafter subjected to conditions capable of initiating polymerization of the component thermosetting resin solids. The finishing composition can be used as a substitute for more expensive or more labor intensive coating compositions in existing surface finishing protocols without compromise of surface quality and chemical resistance.
Patent CA-2390639-A1 (CA)
Title: Process and composition for preparing a lignocellulose-based product, and the product obtained by the process
Inventor: SHOSEYOV ODED
IPC: A01H5/00
Filed: 2000-10-19
Abstract: A process for the manufacture of a lignocellulose product, the process comprising the step of mixing in a reaction medium (i) a phenolic polymer being substituted with a phenolic hydroxy group;  (ii) a lignocellulose containing material having immobilized to a cellulosic fraction thereof a fusion polypeptide, the fusion polypeptide including an enzyme being capable of cat-alyzing the oxidation of phenolic groups and a cellulose binding peptide;  and (iii) an oxidizing agent. A composition of matter for use in the process and a lignocellulose product obtainable by the process are also disclosed.
Patent CA-2391468-A1 (CA)
Title: Smoke detector with sensor having improved mounting configuration
Inventor: OSMANI LULZIM
IPC: G08B17/10
Filed: 2000-11-09
Abstract: A smoke detector (30) has a geometry that locates a sensor or sensors (40) at or near a boundary layer of smoke movement thus facilitating smoke entry into the sensor and/or sensors (40). The sensors (40) are mounted so as to protrude from the bottom of a cover (32b) instead of into the cover (32b) of the detector (30).
Patent CA-2393562-A1 (CA)
Title: Detection of transmembrane potentials by optical methods
Inventor: TSIEN ROGER Y
IPC: C07D335/06
Filed: 2000-12-12
Abstract: Methods and compositions are provided for detecting changes in membrane potential in membranes biological systems. In one aspect, the method comprises: a) providing a living cell with a first reagent comprising a charged hydrophobic molecule which is typically a fluorescence resonance energy transfer (FRET) acceptor or donor, or is a quencher and is capable of redistributing within the membrane of a biological membrane in response to changes in the potential across the membrane; b) providing the cell with a second reagent that can label the first face or the second face of a biological membrane within the cell; c) detecting light emission from the first reagent or the second reagent. One aspect of this method involves monitoring membrane potential changes in subcellular organelle membranes in a living cell. Another aspect of the invention is the use of certain embodiments of the method for the screening of test chemicals for activity to modulate the activity of a target ion channel. Another aspect of the present invention is a transgenic organism comprising a first reagent that comprises a charged hydrophobic fluorescent molecule, and a second reagent comprising a bioluminescent or naturally fluorescent protein.
Patent CA-2393609-A1 (CA)
Title: Speed detecting device mounting structure for a vessel
Inventor: YASHIRO TOMOHIKO
IPC: B63B49/00
Filed: 2002-07-16
Abstract: To provide a speed detecting device mounting structure for a vessel (1) in which the paddle is prevented from being entangled with rubbish and seaweeds in the sea, and the paddle is prevented from being attached with sea-bottom mud or the like. In a vessel comprising a water jet pump provided at the rear portion of the vessel, a ship bottom plate (31) provided below the water jet pump, a speed detecting device (40) mounted on the ship bottom plate (31), and a paddle (61) of the speed detecting device (40) for detecting the flow rate of water flow and obtaining the propelling speed, the speed detecting device mounting structure for a vessel (30) is constructed in such a manner that the paddle (61) of the speed detecting device (40) is disposed on the upper surface of the ship bottom plate (31), an opening (32) is formed at the portion of the ship bottom plate (31) forwardly of the speed detecting device (40), and water taken through the opening (32) is guided to the speed detecting device (40).
Patent CA-2393656-A1 (CA)
Inventor: CRUMP CHET M
IPC: A61M16/00
Filed: 2000-12-04
Abstract: L'invention concerne un cathéter d'aspiration amélioré (200) qui comprend un collecteur (204) destiné à être fixé sur l'embout distal d'une sonde de ventilation trachéale de façon à former un circuit de ventilation, un cathéter (208) pouvant être introduit par ledit collecteur (204) dans ladite sonde de façon à aspirer les sécrétions provenant de la sonde et des poumons, et un mécanisme clapet, disposé adjacent au circuit de ventilation de façon à minimiser la quantité d'air prélevée dans le circuit de ventilation d'un patient pendant le nettoyage du cathéter. Dans un mode de réalisation préféré, le cathéter (208) peut être nettoyé plus à fond que les cathéters existants, tout en prélevant peu ou pas d'air dans le circuit de ventilation du patient.
Patent CA-2395500-A1 (CA)
Inventor: GRIEPENTROG GERD
IPC: H02P27/02
Filed: 2000-12-13
Abstract: Des moteurs asynchrones sont commandés à l'aide d'un gradateur diphasé ou triphasé qui comprend au moins deux paires de thyristors à couplage antiparallèle, qui sont activés à des moments définis. Selon l'invention, une onde fondamentale présentant la fréquence désirée est définie pour la première phase et, dans les autres phases est définie une onde fondamentale qui présente la même fréquence que celle de la première phase mais qui présente un décalage de phase d'une valeur correspondante. Pour chaque phase les moments d'activation pour lesquels la polarité est la même que celle de l'onde fondamentale respective sont marqués. Pour chaque phase sont utilisés les moments d'activation potentiels auxquels il y a un moment d'activation potentiel dans une des deux autres phases. Ces moments sont utilisés en tant que moments d'activation effectifs.
Patent CA-2395737-A1 (CA)
Title: Unit for production of track elements
Inventor: FAHRION OTMAR
IPC: B23K37/04
Filed: 2000-11-18
Abstract: According to the invention, a unit (10) is proposed for the production of track elements (25), which comprises a plurality of clamping devices (14) arranged one after another in the longitudinal direction of the unit. Provided in the clamping devices (14), there is in each case a pedestal element (16), which is fixed to the floor, and a clamping table (24) which is connected at least indirectly to the pedestal element (16). A portion of a track element (25) may be placed on each clamping table (24). In order to enable the prefabrication of track elements (25) whereof the curvature, longitudinal profile and camber are individually different, the clamping tables (24) are positionally adjustable with respect to the particular pedestal element (16).
Patent CA-2397262-A1 (CA)
Inventor: BLANCHARD JEAN CHARLES
IPC: A61P25/34
Filed: 2001-02-07
Abstract: The invention concerns the use of N-piperidino-5-(chlorophenyl)-1-(2,4-dichlorophenyl)-4--methylpyrazole-3-carboxamide to facilitate smoking cessation.
Patent CA-2398381-A1 (CA)
Title: Systeme et bouchon de cimentation instrumente
Inventor: KING CHARLES H
IPC: E21B47/01
Filed: 2001-10-25
Abstract: L'invention concerne un système de cimentation d'un élément tubulaire (11) dans un forage constitué d'un bouchon de cimentation (29). Le bouchon de cimentation (29) comprend au moins un capteur (41,43,47,49). Le système transmet une valeur mesurée par le capteur à un emplacement de surface. Il peut transmettre la valeur mesurée par le capteur par l'intermédiaire d'un câble (33) relié entre le bouchon (29) et l'emplacement de surface. Dans un autre mode de réalisation, le système peut transmettre de façon acoustique à l'emplacement de surface la valeur mesurée par le capteur.
Patent CA-2399109-A1 (CA)
Title: T cell receptor libraries
Inventor: KESSELS HELMUT WILHELMUS HUBER
IPC: C40B40/02
Filed: 2001-01-15
Abstract: The present invention provides a strategy for TCR-display that closely mimic s the in vivo situation, meaning at least a stable expression of TCRs to he displayed in mammalian cells exemplified b y retroviral insertion of a T cell receptor library into a TCR-negative T cell host. Such mammalian cell line TCR libraries, especial ly T cell line-displayed TCR libraries woud not only allow the selection of desirable TCRs by biochemical means. but also offer t he possibility to directly test the functional behavior of selected TCRs. By generating a TCR library that is diersified in its CDR3bet a structure, we were able to select novel TCRs that either share specificity with the parental TCR, or that have acquired a specificity  for a variant T cell epitope. A change in TCR specificity can be thought of as an increase in TCR affinity for the variant epitope.</S DOAB>
Patent CA-2400724-A1 (CA)
Title: Porous ferro- or ferrimagnetic glass particles for isolating molecules
Inventor: SAUER PHILIPPE
IPC: B03C1/00
Filed: 2001-03-22
Abstract: Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use of identifying or separating molecules of interest are also described. Kits comprising the porous, ferro-  or ferrimagnetic, glass particles are also provided.
Patent CA-2405340-A1 (CA)
Inventor: BUSTOS RAFAEL T
IPC: A47F1/12
Filed: 2002-09-25
Abstract: A product fronting assembly and method for fronting product is provided. In some embodiments, the assembly includes a base having a bottom, a front, a rear, and opposite sides. The assembly can also include a frame slidable within the base and having a front at least partially defining a handle and opposed sides coupled to the front of the frame. The opposed sides can be spaced a distance apart and between which product upon the base is received, and can be positioned to rest and slide upon the bottom and/or sides of the base. In some embodiments, the frame also includes a rear coupled to the opposed sides and movable by movement of the front of the frame to front product in the assembly.
Patent CA-2405509-A1 (CA)
Inventor: DIETZEL BERND
IPC: F16H61/12
Filed: 2002-02-01
Abstract: The invention relates to a method for early recognition of abnormal occurrences in the operation of automatic or automated gearboxes wherein at least one variable A kraftschl, directly or indirectly characterizing the strain on elements which are to be coupled to each other in a non-positive fit is continuously determined after an n-th shift at least until a synchronous rev speed is reached or during a maximum shift period T max; wherein the variable A kraftschlüssig characterizing the strain on the elements that are to be coupled is mathematically combined with the time, or if several variables A kraftschlüssig Exist, said variables are mathematically combined with each other and the product of said combination is added up in the form of a variable W sum; wherein the product thereof is compared with a first pre-definable or defined threshold value W max0 Which, if exceeded, defines a state from which damage can be deduced and the shift action is aborted.
Patent CA-2406804-A1 (CA)
Title: A method for sequestering a fluid within a hydrocarbon containing formation
Inventor: MAHER KEVIN ALBERT
IPC: E21B43/243
Filed: 2001-04-24
Abstract: A method for sequestering a fluid is disclosed, which method comprises sequestering the fluid within a portion of an in-situ heat treated hydrocarbon containing formation, such as a coal seam in which hydrocarbons have been pyrolysed, of which at least a portion has preferably a permeability of at least 100 millidarcy.
Patent CA-2407476-A1 (CA)
Title: A nutritional composition for dietary supplements
Inventor: KNUDSEN LEIF
IPC: A23L33/115
Filed: 2001-05-01
Abstract: By the present invention, a nutritional composition is provided for use as a  nutritional supplement to a diet on a regular basis, e.g. on a daily basis. The composition comprises vitamin compounds comprising a selection of vitamins, mineral compounds comprising a selection of minerals, and fish oil  granulate in dry pulverised form comprising eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Hereby, a comprehensive nutritional supplement i s provided by which the diet may be supplemented not only by minerals and vitamins but also by the omega-3 fatty acids EPA and DHA of the fish oil granulate. Side effects such as bad taste and smell are removed by using the  fish oil granulate.
Patent CA-2412537-A1 (CA)
Title: Procede pour produire des compositions de type sol-gel presentant une teneur reduite en solvant et une stabilite au stockage amelioree, et utilisation desdites compositions
Inventor: MAGER MICHAEL
IPC: C08G77/50
Filed: 2001-06-18
Abstract: L'invention concerne un procédé pour produire des matériaux (hybrides) inorganiques ou organiques-inorganiques par hydrolyse et condensation d'alcoxydes monomoléculaires ou à faible poids moléculaire, ainsi que l'utilisation de ces matériaux pour revêtir des surfaces et modifier des polymères organiques.
Patent CA-2413066-A1 (CA)
Title: Fluid permeable flexible graphite fuel cell electrode
Inventor: MERCURI ROBERT ANGELO
IPC: H01M50/528
Filed: 2001-06-21
Abstract: A membrane electrode assembly is provided. More particularly, an assembly is  provided which includes a pair of electrodes (20) and an ion exchange membra ne (550) positioned between the electrodes, at least one of the electrodes (10)  being formed of a sheet of a compressed mass of expanded graphite particles (80) having a plurality of transverse fluid channels (1400) passing through the sheet between first and second opposed surfaces of the sheet, one of opposed surfaces abutting the ion exchange membrane (550). The surfaces of a t least some of the transverse fluid channels (1400) have glassy carbon thereo n or therein.
Patent CA-2413758-A1 (CA)
Inventor: LESHO JEFFREY C
IPC: G08C17/00
Filed: 2001-06-27
Abstract: Un système de mesure quantitative comprend une unité externe (101a) et une unité interne (102a) permettant d'obtenir des mesures quantitatives de mélange à analyser, à l'intérieur du corps, par exemple. Dans un exemple de l'application du système, l'unité interne (102a) peut être implantée soit sous la peau, soit ailleurs dans le corps d'un sujet. L'unité interne (102a) contient des circuits opto-électroniques (102b), un composant desquels pouvant être constitué d'un dispositif de détection fluorescent. Les circuits opto-électroniques (102b) obtiennent des informations de mesure quantitative et modifient une charge (102c) en fonction des informations obtenues. La charge (102c) fait, à sont tour, varier la quantité de courant à travers la bobine (102d), laquelle est couplée à une bobine (101f) de l'unité externe (101a). Un démodulateur (101b) détecte les variations de courant induites dans la bobine externe (101f) par la bobine interne (102d) couplée à celle-ci, et applique le signal détecté aux circuits de traitement, tels qu'un compteur d'impulsions (101c) et une interface informatique (101d), en vue de traiter le signal dans un format lisible par un ordinateur afin de l'entrer dans un ordinateur (101e).
Patent CA-2414252-A1 (CA)
Inventor: FELD HARALD
IPC: B27G15/00
Filed: 2002-12-13
Abstract: In a cylindrical bore head tool including a shaft part with a head support structure and a bore head disposed on the bore head support structure, the bore head support structure with the shaft are an integral part made of tool steel and the cutting head is a sintered hard metal body, and the bore head support structure and the bore head include cooperating form-locking elements by which the bore head is centered on the bore head support structure and rotationally firmly engaged there-with.
Patent CA-2420860-A1 (CA)
Title: Device for electrical stimulation and sensing of muscles and nerves of the intravaginal cavity
Inventor: EINI MEIR
IPC: A61B5/0488
Filed: 2001-08-30
Abstract: A device for stimulating muscles and nerves defining and surrounding an intravaginal cavity of an individual and/or sensing tonus and/or electrical activity of muscles defining and surrounding an intravaginal cavity (10) is provided. The device (10) includes (a) a body (12) having memory properties such that when the body (12) is contracted and positioned within an intravaginal cavity of the individual the body (12) self expands to conform to a contour of the intravaginal cavity; and (b) at least one pair of electrode s (14) being attached to an exterior surface of the body (10) such that when t he body (10) is positioned within the intravaginal cavity, each electrode (14) of the at least one pair of electrodes (14) is biased against a wall of the intravaginal cavity. Thus they maintain electrical contact with the wall.</S DOAB>