baber/WOPTO huggingface dataset:
Patent CA-3109782-A1 (CA)
Inventor: HENDERSON MICHEAL LORENZO
IPC: B62D37/00
Filed: 2011-05-04
Abstract: A rain gutter component for managing airflow over a cargo enclosure is described, the rain gutter comprising a sloped surface extending between a leading edge and a trailing free edge, the rain gutter component being configured to be positioned adjacent to a roof of the cargo enclosure such that including the leading edge contacts the roof when secured to the cargo enclosure in an operating aerodynamic configuration, the rain gutter component extends from the leading edge across a first portion of the roof and then decreases as the rain gutter component extends towards the trailing free edge along a second portion of the roof, wherein the rain gutter component is adapted to be non-movably attached to the cargo enclosure such that the portion of the rain gutter component contacting the roof is maintained in a fixed position relative to the roof.
Patent CA-3113416-A1 (CA)
Inventor: MAZOR MEITAL
IPC: A61B18/02
Filed: 2019-09-18
Abstract: La présente invention concerne, dans des modes de réalisation, des méthodes de traitement de graisse viscérale, les méthodes comprenant les étapes consistant à identifier une graisse viscérale à traiter, insérer un dispositif laparoscopique dans la graisse viscérale à traiter, insérer un instrument de traitement dans le dispositif laparoscopique de telle sorte qu'une section de traitement distale du dispositif de traitement est placée dans la graisse viscérale, refroidir la section de traitement distale et la graisse viscérale adjacente à la section de traitement distale à une température de refroidissement inférieure ou égale à environ -20 °C, et réchauffer la section de traitement distale et la graisse viscérale adjacente à la section de traitement distale à une température supérieure à la température de refroidissement.
Patent CA-3115807-A1 (CA)
Title: Procedes de prise de decisions de traitement du cancer de la prostate
Inventor: WONG VIVIEN
IPC: G06K9/00
Filed: 2019-10-11
Abstract: L'invention concerne des procédés d'évaluation du risque de cancer de la prostate d'un patient. Les procédés sont également dirigés vers ou peuvent en outre consister à traiter le sujet et/ou à prendre des décisions de gestion de traitement sur la base de l'évaluation.
Patent CA-3115924-A1 (CA)
Title: Systems and methods for traffic priority systems
Inventor: CROSS BRAD
IPC: G08G1/0965
Filed: 2019-10-09
Abstract: Use of a mobile user device to identify the individual operating a vehicle, which, either alone or in conjunction with a vehicle control unit (VCU), may be used to establish vehicle priority in connection with traffic control systems. This provides for a system that provides priority for the individual based on their individual and current need for priority, as opposed to providing priority generally for a vehicle.
Patent CA-3116141-A1 (CA)
Inventor: YOSHIKAWA KENJI
IPC: C07D239/94
Filed: 2019-12-05
Abstract: Chromosomal translocation of the MLL (Mixed-Lineage Leukemia) gene is observed for infant leukemia and some poor-prognosis leukemia cases. MLL, as a result of chromosomal translocation, fuses with 70 or more various translocation partner genes at the amino terminus thereof to express an MLL fusion protein. Wild-type MLL constructs a transfer regulation complex that modifies the chromatin structure, and specifically methylates lysine at position 4 of histone H3, playing a very important role in the transcription regulation of gene clusters (for example, HOX gene cluster, etc.) involved in hematogenesis and neogenesis. Meanwhile, the MLL fusion protein, the expression thereof being induced by chromosomal translocation, has lost the histone methylation enzyme activity, but activates gene clusters (for example, HOX and MEIS1 genes, etc.) involved in the cell differentiation control permanently. As a result, abnormal cell proliferation and inhibition of differentiation induction of hematopoietic cells are triggered, which leads to onset of leukemia. Leukemia involving a mutant MLL gene has poor prognosis, and the standard treatment used for leukemia treatment today does not demonstrate full effectiveness. For this reason, the development of new regimen of therapy is in strong demand. Menin is a tumor-suppressor protein identified as a causal factor of multiple endocrine neoplasia type 1 (MEN1), which is one of autosomal dominant inherited neoplasia syndromes, characterized by the tumor formation in multiple endocrine organs. Menin is a ubiquitously expressed nucleoprotein, interacts with a wide variety of proteins, and is involved in various cellular processes. It is considered that the biological functions of menin can be tumor-suppressing or tumor-promoting, depending on the cell context. Menin interacts with the amido terminus of MLL1, and functions as carcinogenic cofactor that increases the transcription of gene clusters such as HOX and MEIS1. It is known that the interaction between menin and an MLL fusion protein is essential for abnormal activation of a series of gene clusters and onset of leukemia caused by the MLL fusion protein (non-patent documents 1 and 2). Thus, it is expected that inhibition of the interaction between menin and an MLL fusion protein contributes to the treatment and/or prevention of leukemia involving MLL gene chromosomal translocation and other leukemia/hematological cancer accompanied by constant expression of HOX and MEIS1 genes. Accordingly, for example, the creation of a drug that inhibits the interaction between menin and an MLL fusion protein is of great significance from the perspective of providing a novel option for cancer treatment. A plurality of compounds are already known to exhibit inhibitory activity against the interaction between menin and an MLL protein (patent documents 1 to 4, non-patent documents 3 to 5).
Patent CA-3116823-A1 (CA)
Title: Handoffs between access points in a wi-fi environment
Inventor: BENCHEIKH AHMED
IPC: H04W36/30
Filed: 2013-04-03
Abstract: Techniques disclosed herein include systems and methods for providing active mobility of Wi-Fi enabled devices within a given wireless local area network (WLAN). In general, techniques include dynamically commanding Wi-Fi enabled devices to disconnect from a corresponding access point in response to meeting predetermined conditions. A forced disconnect can be based on various criteria such as low-power or lost packet thresholds triggering the forced disconnect. Such techniques cause a Wi-Fi enabled device to disconnect from one access point and connect to another access point before a connection quality deteriorates to a point that causes noticeable interruptions in connectivity or a generally poor experience, thereby enabling a smooth transition among access points.
Patent CA-3120311-A1 (CA)
Title: Systems and methods for providing audio-video streams with alternative content
Inventor: ROBERTSON MARK W
IPC: H04N21/6587
Filed: 2021-05-31
Abstract: ABSTRACT Systems, devices, and methods for providing alternative content in audio-video streams are disclosed. A manifest data structure including data reflective of a plurality of content segments of an audio-video stream is generated. At least one alternative content indicator is obtained, each corresponding to and indicating one of the plurality of content segments as being an alternative content segment of one or more alternative content segments, wherein the one or more alternative content segments are a subset of the plurality of content segment . The manifest data structure is modified to remove data reflective of those of the plurality of content segments that are not indicated by the one of the alternative content indicators as being an alternative content segment. Upon receiving a request from a client device to view alternative content, the modified manifest data structure is sent to the client device. Date Recue/Date Received 2021-05-31
Patent CA-3121298-A1 (CA)
Title: Method and system for audio-visual live content delivery
Inventor: BALE SOPHIE
IPC: H04L29/08
Filed: 2018-11-28
Abstract: An audio-visual live content delivery system includes: a client (110) having access to a provider network (102) via a gateway (140); an audio-visual live content delivering equipment (120) comprising a multicaster for transmitting audio-visual live contents in multicast form via the provider network (102); a de-multicaster (150) being able to perform a conversion in unicast form of audio-visual live contents received in multicast form from the multicaster; and a controller (130) managing routing of requests to get audio-visual live contents. The client (110) performs a discovery procedure aiming at receiving information on potential presence and availability of the de- multicaster (150). When the client (110) intends receiving a targeted audio-visual live content, the client (110) sends to the controller (130) a request providing indication of presence and availability, or not, of the de-multicaster (150). Then the controller (130) decides how redirecting the client (110) to fulfill the request, according at least to the indication of presence and availability, or not, of the de-multicaster (150).
Patent CA-3125310-A1 (CA)
Title: Double stranded rna and uses thereof
Inventor: GONCALVES PEREIRA NOBRE RUI JORGE
IPC: A61K31/713
Filed: 2020-01-09
Abstract: The present disclosure relates to a non-invasive and allele-specific treatment, in particular for Machado- Joseph disease (MJD). The present disclosure uses RNA silencing technology (e.g. RNA interference) against exonic single nucleotide polymorphisms (SNPs) in the ataxin-3 gene, encoding the dominant gain- of-function mutant ataxin-3 protein, thereby resulting in an effective treatment for MJD. For that purpose, highly-target specific gene silencing RNAs, whose anti-sense sequences are complementary to SNPs that are in linkage disequilibrium with the disease-causing expansion, were designed and tested. Furthermore, this disclosure also relates to a selected adeno-associated viral vector, in particular serotype 9 (AAV9) as a gene delivery vector, upon which the said double stranded RNAs can be delivered into the central nervous system (CNS) by minimally invasive routes (e.g. intravenous administration), since this particular serotype efficiently crosses the blood-brain barrier (BBB).
Patent CA-3129953-A1 (CA)
Inventor: SAXENA PRATEEK
IPC: D21J7/00
Filed: 2020-03-12
Abstract: L'invention concerne un procédé comprenant les étapes suivantes : activation de la source de vide (10), injection d'une quantité de pâte dans la chambre de moule interne (3) à travers l'ouverture de moule (7), formant ainsi une préforme de cellulose sur la surface de moule interne (8), injection d'un fluide de déshydratation et de chauffage à travers l'ouverture de moule à une pression progressivement croissante jusqu'à une pression maximale, réalisant ainsi une étape de déshydratation et de séchage, la préforme de cellulose sur la surface de moule interne étant déshydratée et séchée, désactivation de l'injection de déshydratation et de fluide de chauffage, désactivation de la source de vide, et extraction du produit de cellulose moulée. L'invention concerne en outre une étape d'initiation de la rotation du moule (2) autour de l'axe central (4) du moule et d'augmentation progressive de la vitesse de rotation, de réception principale d'une vitesse de rotation maximale du moule au moins pendant une partie substantielle de l'étape de déshydratation et de séchage, et de diminution de la vitesse de rotation progressivement jusqu'à l'arrêt du moule.
Patent CA-3130183-A1 (CA)
Title: Systeme de commande synchrone d`ampoules et ampoules commandees de maniere synchrone
Inventor: WU QINGAN
IPC: H05B45/40
Filed: 2021-08-30
Abstract: Un système de commande synchrone dampoules comprend un appareil redresseur connecté à une tige de ligne en continu et une ligne neutre dune alimentation électrique externe, un appareil déchantillonnage connecté à lappareil redresseur ou à lalimentation électrique externe pour compter un nombre de changements dans un cycle et obtenir une longueur de cycle du courant alternatif ou dune impulsion de signal de commande de manière à fournir un signal de synchronisation et acquérir une entrée de signal de commande par un dispositif de commande externe, un appareil de commande pour la réception du signal de synchronisation et pour la commande de la sortie de signal de commande et/ou de synchronisation par lappareil déchantillonnage, un appareil dalimentation électrique dunité de commande principale connecté respectivement à lappareil redresseur et à lappareil de commande pour alimenter électriquement ce dernier, et un assemblage de diode électroluminescente (DEL) comprenant au moins une unité de DEL qui est connectée respectivement à lappareil redresseur et à lappareil de commande et qui est commandée par ce dernier.
Patent CA-3132681-A1 (CA)
Title: Processes for converting petroleum based waste oils into light and medium distillate
Inventor: KARL DANIEL BRUCE
IPC: C07C4/06
Filed: 2020-03-06
Abstract: The present technology relates to processes for converting PBWO into light and medium distillate such as usable diesel fuel, the processes generally comprising the steps of: boiling the PBWO to dehydrate the PBWO, heating the PBWO to produce PBWO hydrocarbon vapor, contacting the PBWO hydrocarbon vapor with a catalyst, and cooling the resultant vapor to liquid form through heat exchangers to produce light and medium distillate.
Patent CA-3132802-A1 (CA)
Inventor: Yuan yongan
IPC: C04B14/06
Filed: 2020-05-06
Abstract: Disclosed is a gypsum panel comprising a gypsum core comprising set gypsum and a colloidal material comprising colloidal silica, colloidal alumina, or both.
Patent CA-3133826-A1 (CA)
Inventor: YIP STEPHEN
IPC: G01N1/30
Filed: 2020-03-25
Abstract: A generalizable and interpretable deep learning model for predicting biomarker status and biomarker metrics from histopathology slide images is provided.
Patent CA-3135070-A1 (CA)
Inventor: LI XIN
IPC: A61K31/519
Filed: 2020-03-27
Abstract: The present application provides a pyrroloheterocyclic derivative, a preparation method therefor, and an application thereof in medicine. Specifically, the present application provides a novel pyrroloheterocyclic derivative as represented by formula (I), a preparation method therefor, a pharmaceutical composition comprising the derivative, and an application of the derivative as a therapeutic agent, particularly as an ERK inhibitor, wherein substituents in the formula have the same definitions as those in the description.
Patent CA-3137687-A1 (CA)
Title: Pluripotent cell aggregates and use thereof
Inventor: LAVON NETA
IPC: C12N5/0793
Filed: 2020-05-14
Abstract: The present invention relates to compositions and methods for mass production of pluripotent stem cells derived from non-human-animal, particularly in a form of aggregates suitable for a variety of uses, particularly to mass production of aggregates of bovine-derived pluripotent stem cells for use in cell grown meat cultures and in production of cell based meat products.
Patent CA-3138648-A1 (CA)
Inventor: WANG FENG
IPC: C07D491/10
Filed: 2020-05-21
Abstract: The present invention relates to an indole derivative-containing inhibitor, a preparation method therefor and an application thereof, and in particular, to a compound as represented by general formula (Ia), a preparation method therefor, a pharmaceutical composition comprising the compound, and the use thereof in treating related diseases such as cancer, inflammation, chronic liver disease, diabetes, cardiovascular disease, and AIDS as a kinase inhibitor, especially as a receptor tyrosine kinase inhibitor (TKI), more specifically, as an EGFR or HER2 inhibitor. The compound exhibits good inhibitory activity in EGFR and HER2 20 exon mutations.
Patent CA-3139958-A1 (CA)
Inventor: KAUPPINEN PASI
IPC: B62J43/00
Filed: 2020-05-28
Abstract: L'invention concerne une trottinette à neige (100), qui comprend - un cadre (10) comprenant une première extrémité (23) et une seconde extrémité (24), le cadre (10) formant une plateforme pour se tenir debout (25) pour un utilisateur (102), - une colonne de direction (21) reliée à la première extrémité (23) du cadre (10) de manière articulée pour diriger la trottinette à neige (100), - un mobile de direction (8) relié à l'extrémité inférieure (28) de la colonne de direction (21) pour supporter la trottinette à neige (100) sur une surface d'un substrat (104), - une unité d'entraînement de chenille (14) reliée à la seconde extrémité (24) du cadre (10) pour supporter la trottinette à neige (100) sur la neige (104) et pour transmettre une poussée à la surface du substrat (104), - un moteur électrique (2) pour entraîner l'unité d'entraînement de chenille (14), agencé à l'intérieur de l'unité d'entraînement de chenille (14), et - une batterie (11) pour stocker de l'électricité pour le moteur électrique (2). Le cadre (10) comprend un espace de batterie (32) formé dans le cadre (10) pour la batterie (11), l'espace de batterie (32) étant formé conjointement avec la première extrémité (23) du cadre (10) devant l'unité d'entraînement de chenille (14) dans la direction de déplacement de la trottinette à neige (100) de façon à diriger le poids de la batterie (11) sur le mobile de direction (8) afin d'améliorer la capacité de direction.
Patent CA-3142594-A1 (CA)
Title: Explosives based on hydrogen peroxide with improved sleep time
Inventor: KETTLE ANDREW
IPC: C06B23/00
Filed: 2020-06-05
Abstract: The present invention provides an explosive composition comprising hydrogen peroxide, fuel and one or more density stabilisers. The present invention also provides methods for preparing the compositions and method of using the compositions. 5
Patent CA-3144727-A1 (CA)
Inventor: GALZIN GUILLAUME
IPC: B64D13/08
Filed: 2020-07-24
Abstract: Air conditioning system for an aircraft cabin, comprising a primary exchanger (14) configured to cool collected air (12) originating from at least one aircraft compressor, a pre-compressor (18), an intermediate exchanger (20), a main compressor (22) configured to compress the collected pre-compressed air, a main exchanger (28) configured to cool the collected compressed air, and a water extraction loop, characterised in that the system comprises a pipe (108) for recovering at least part of the air from the cabin after it has passed through the cabin, and pipes for circulating the recovered air which are configured such that the recovered air consecutively passes through a secondary exchanger (34), the recovered air forming a first cold source for cooling the collected air again, a heat exchanger (20), the recovered air forming a second cold source for cooling the collected air, a turbine (48) for recovering energy, the recovered air forming an energy source.
Patent CA-3144846-A1 (CA)
Title: Novel boronic acid containing peptidomimetics as malarial serine protease inhibitors
Inventor: JIRGENSONS AIGARS
IPC: A61K38/55
Filed: 2020-04-09
Abstract: The invention relates to novel boric acid-containing peptidomimetics I, (I) acting as inhibitors of the malaria subtilisin-related serine protease (SUB). They are useful as medicinal preparations or as ingredients for the treatment of malaria.
Patent CA-3145410-A1 (CA)
Inventor: YANG GUANG
IPC: C07K16/28
Filed: 2019-07-02
Abstract: The present technology relates generally to compositions and methods of preventing or treating diseases associated with mutantleptin receptors, leptin deficiency or leptin dysfunction. The present technology also relates to administering the anti-leptin receptor antibodies in effective amounts to treat a subject suffering from, or predisposed to, a disease associated with mutant leptin receptors, obesity, leptin deficiency, leptin resistance, and/or hypoleptinemia.
Patent CA-3146687-A1 (CA)
Inventor: HU KEBIAO
IPC: A47H1/142
Filed: 2022-01-26
Abstract: A rod holder includes a first socket, the first socket located at the top of the rod holder, being C-shaped, and opening forward. A second socket is located below the first socket, is N-shaped, and opens downward. An U-shaped cradle resides opposite the first socket from the second socket and opens upward. A rod holder body has a first end connected to the first and second sockets and a second end connected to the cradle. The first and second sockets reside in a plane, and the cradle resides forward of the plane and the rod holder body extends rearward from the plane. The cradle may include one or more protrusions proximate to its opening. A method of installing a rod holder is also provided.
Patent CA-3147087-A1 (CA)
Title: Time-accurate cfd enhanced interpretation of strain-based flow measurement
Inventor: GYSLING DANIEL L
IPC: G01F1/20
Filed: 2020-08-12
Abstract: A system for measuring a velocity or volumetric fluid flow rate of a fluid flow passing within a pipe includes a SONAR flow meter configured to determine a measured velocity or volumetric rate of a fluid flow passing within a pipe. The system further includes a CFD analysis device configured to produce a simulated velocity or volumetric rate of the fluid flow passing within the pipe. The system further includes a processing unit in communication with the CFD analysis device and the SONAR flow meter. The processing unit is configured to produce at least one error function based on the measured velocity or volumetric fluid flow rate and the simulated velocity or volumetric fluid flow rate, and is configured to determine an adjusted velocity or volumetric fluid flow rate using the at least one error function and the measured velocity or volumetric fluid flow rate.
Patent CA-3148959-A1 (CA)
Inventor: LITTLE TROY M
IPC: B65D5/20
Filed: 2022-02-15
Abstract: A retail-ready container includes internal corner supports. The container is erected from a preassembly formed from a single blank. The blank includes a side panel, a bottom panel, and an auxiliary panel. Each of the side panel and the auxiliary panel include a plurality of sections connected by respective fold lines. The auxiliary panel is folded against the side panel and sections of the auxiliary panel are adhered to corresponding sections of the side panel. Fold lines of the side panel are laterally offset from fold lines of the auxiliary panel so that unfolding of the preassembly yields the container with internal corner supports.
Patent CA-3149118-A1 (CA)
Inventor: LEVY JEAN-CHRISTOPHE
IPC: H04B7/185
Filed: 2020-07-29
Abstract: The invention relates to a method for determining operational constraints for a first constellation of non-geostationary satellites (CONS_I) transmitting in the direction of a ground station (SV) with respect to a second constellation of non-geostationary satellites (CONS_V) linked to the station, the constraints comprising a maximum transmission power of the satellites of the first constellation, the method comprising: - determining triplets of limiting values (?, ?, I/N) of two angles (?, ?) and of an interference-to-noise ratio (I/N), the angles (?, ?) defining a position of a satellite (NGSO_I) of the first constellation with respect to the station and to a satellite (NGSO_V) of the second constellation and the interference-to-noise ratio being the ratio between the interference (I) transmitted by the first constellation over a link between the station and the satellite of the second constellation and the noise (N) of the link, the triplets being determined so that a distribution of signal-to-noise and signal-to-interference ratios (R) summed over a time interval is higher than a reference distribution (REF); - determining at least the maximum transmission power of at least one satellite of the first constellation on the basis of the triplets.