baber/WOPTO huggingface dataset:
Patent FI-943280-A (FI)
Inventor: WONG PATRICK S-L
IPC: A61K9/00
Filed: 1994-07-08
Abstract: The present invention is directed to a fluid-imbibing drug delivery device which is useful for the initial delayed delivery of an active agent formulation to a fluid environment of use, the initial delay period to startup or activation being of a predetermined length of time. The delivery of the agent formulation from the dispensing device, once begun, is continued over a predetermined prolonged period of time.
Patent FI-945227-A (FI)
Inventor: WAKIMASU MITSUHIRO
IPC: C07K14/575
Filed: 1994-11-07
Abstract: A cyclic hexapeptide represented by the formula:    cyclo[A-Asp(R<1>)-Y-NH-CHR<2>-CO-C-D-Trp(N<in>-R<3>)-]   (I> wherein A is a D-acidic- alpha -amino acid residue; Y is an acidic- alpha -amino acid residue; C is an L- alpha -amino acid residue; R<1> is a group represented by the formula: <CHEM> wherein X<1> and X<2> are independently H, C1-6 alkyl, C1-6 alkoxy, halogen or nitro, and may bind together to form a ring in cooperation with the adjacent carbon atom; R<2> is C1-6 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-C1-3 alkyl, C1-6 alkylthio-C1-3 alkyl, C3-7 cycloalkylthio-C1-3 alkyl, C1-5 alkoxy-C1-3 alkyl, C3-7 cycloalkoxy-C1-3 alkyl, C1-6 alkylthio, C3-7 cycloalkylthio, C1-5 alkoxy or C3-7 cycloalkoxy; R<3> is H, C1-6 alkyl, C3-7 cycloalkyl, -COR<4>, - COOR<5> or -CONHR<6>; when X<1>, X<2> and R<3> are all hydrogen atoms, R<2> is not an isobutyl group, or a saalt thereof, which exhibits excellent antagonistic action against endothelin receptors, particularly endothelin B receptors.
Patent FI-950800-A (FI)
Inventor: CASADO MICHEL
IPC: C07D231/44
Filed: 1995-02-21
Abstract: Process for the sulphinylation of heterocyclic cpds. comprises reaction of a deriv. of formula RS(O)X with a heterocyclic cpd. Het. R = 1-4C alkyl (opt. substd. by one or more halo); X = halo, hydroxy(or one of its salts), -NR2R3 or aryloxy; R2, R3 = 1-4C alkyl or haloalkyl; aryl = pref. phenyl (opt. substd. by one or more halo or 1-4C alkyl or haloalkyl); Het = a pyrrole, pyrazole, imidazole, oxazole, iso-oxazole, isothiazole, thiazole or triazole (all opt. substd. by one or more halo, amino, mono- or di-alkylamino, nitrile or aryl (opt. substd. by one or more halo and/or one or more alkyl, haloalkyl or SF5); provided that R is not n-butyl when Het = pyrrole and R is not methyl when Het = 2,5-dimethyl pyrrole. Intermediates RS(O)NH-Het are new.
Patent FI-951996-A (FI)
Inventor: VENET MARC GASTON
IPC: A61P31/04
Filed: 1995-04-26
Abstract: PCT No. PCT/EP93/02884 Sec. 371 Date Apr. 4, 1995 Sec. 102(e) Date Apr. 4, 1995 PCT Filed Oct. 19, 1993 PCT Pub. No. WO94/10164 PCT Pub. Date May 11, 1994The present invention is concerned with novel quinoline derivatives having anti-Helicobacter activity of formula    <IMAGE>  (I)  the pharmaceutically acceptable acid addition salts thereof, the stereochemically isomeric forms thereof, the quaternized forms thereof and the +E,uns N+EE -oxides thereof, wherein -A- represents a bivalent radical of formula -N=CH-CH=CH-(a), -CH=N-CH=CH-(b), -N=N-CH=CH-(c), -N=CH-N=CH-(d), -N=CH-CH=N-(e), -CH=N-N=CH-(f), -N=N-N=CH-(g), -N=N-CH=N-(h), or -CH=CH-CH=CH-(i); R1, R2, R3, R4, R5, R6 and R7 each independently represent hydrogen, halo, hydroxy, C1-4alkyloxy, C1-4alkyl, trifluoromethyl, amino, mono- or di(C1-4alkyl)amino or nitro, provided that when one substituent on a phenyl group is a nitro then the other substituents on said phenyl group are other than nitro; novel compositions comprising said compounds, processes of preparing said compounds and compositions and methods for treating subjects suffering from disorders or afflictions associated with Helicobacter infection.
Patent FI-960781-A (FI)
Inventor: SPEICH HELMUT
IPC: A61G7/10
Filed: 1996-02-21
Abstract: The hoist and support device comprises a mobile support column (2) which has at least one roller (11,12) near and on each side of its free end (10). The roller extends beyond the end of the support column. The roller axle (13) goes through the centre of the column end. The roller is pref. mounted on a pivot lever which has a pedal in the form of a two-armed lever spaced a little apart from the roller.
Patent FI-960980-A (FI)
Inventor: NOELLE RANDOLPH J
IPC: A61K35/28
Filed: 1996-03-01
Abstract: Methods for inducing antigen-specific T cell tolerance are disclosed. The methods involve contacting a T cell with: 1) a cell which presents antigen to the T cell, wherein a ligand on the cell interacts with a receptor on the surface of the T cell which mediates contact-dependent helper effector function; and 2) an antagonist of the receptor on the surface of the T cell which inhibits interaction of the ligand on the antigen presenting cell with the receptor on the T cell. In a preferred embodiment, the cell which presents antigen to the T cell is a B cell and the receptor on the surface of the T cell which mediates contact-dependent helper effector function is gp39. Preferably, the antagonist is an anti-gp39 antibody or a soluble gp39 ligand (e.g., soluble CD40). The methods of the invention can be used to induce T cell tolerance to a soluble antigen or to an allogeneic cell. The methods of the invention can also be used to induce tolerance in cases of bone marrow transplantation and other organ transplants and to inhibit graft-versus-host disease.
Patent FI-961085-A (FI)
Inventor: MAEENPAEAE MARKKU
IPC: E05B/
Filed: 1996-03-08
Abstract: The invention relates to a lock 1 in particular for locking a plane part 2 such as a door. The lock 1 is fastened, by a hinge or the like, in a support construction such as a door case, it being possible to open the part 2 when the lock 1 is in an open state. The part 2 comprises a front surface 2a located in the opening direction 6, and a rear surface 2b located on the opposite side, and the lock 1 comprises a locking means 4 and a lock box 3 for fastening in the door 2. The locking means 4 is arranged so as to project at least partly from the rear surface 2b of the part 2, and the locking means 4 is arranged so as to be transferable partly behind the support construction 5, the locking means 4 and the support construction 5 preventing opening of the part 2. <IMAGE>
Patent FI-961103-A (FI)
Inventor: LARSEN BJARNE RUDOLF EBBESKOV
IPC: C02F7/00
Filed: 1996-03-08
Abstract: The invention concerns a method for the oxidation and cleaning of aqueous environments ranging from lakes and streams to swimming pools. The invention also concerns a device for the practice of the method as well as the use of the device. The invention consists of a reaction vat (1) for submergence in liquid (100). In the reaction vat (1) there is a rotor which causes a downward rotating current in the reaction vat. Above the reaction vat (1) a mixture of ozone and UV-irradiated liquid is conducted and is in turn sucked down and mixed with the liquid that is to be conditioned during the rotating downward current. The invention can be used for the oxidation and disinfection of both sensitive biological environments such as lakes, streams, etc., and less sensitive environments like swimming pools and the like, since the conditioning ozone can either be ozone produced using UV-irradiation or so-called high tension ozone, also known as corona ozone.
Patent FI-964042-A (FI)
Inventor: URBY LARS
IPC: E05B47/00
Filed: 1996-10-09
Abstract: A lock mechanism includes a lock bolt mechanism (6), for instance a key actuated mechanism, having a lock bolt (20a) and a latch bolt mechanism (4) including a latch bolt (9) and actuated by a follower lever (17). Movement of the lock bolt (20a) between its terminal positions is generated and stepped-up, or geared, through the medium of a connecting rod (24) and a transmission lever (22). The mechanism also includes a locking lever (32) and a coupling lever (27) and a dogging lever (31) by means of which the follower lever (17) of the latch mechanism (4) can be actuated to retract the latch bolt (9), for instance by turning a key. The lock mechanism is constructed in accordance with a module system for adaptation to different backsets and centre distances, cylinder/knob. The lock mechanism is adapted to suit differing backsets by using one or more connecting rods (24) having one or more alternative points (24a) of pivotal attachment to the transmission arm. The remainder of the lock bolt mechanism remains essentially unchanged when making such adjustments, possibly with the exception of the coupling lever (27). With regard to the latch bolt mechanism, a press rod (10) having a length commensurate with a relevant backset is exchangeably mounted in position while the remainder of the latch mechanism (4) remains essentially unchanged. Quick-release levers (39) of different lengths commensurate with different cylinder-knob centre-to-centre distances can be exchangeably mounted on a pivot shaft (38) in the region of the edge of the lock housing distal from the latch and lock bolts.
Patent FI-971289-A (FI)
Inventor: JOHANSSON SIXTEN
IPC: B65D19/00
Filed: 1997-03-26
Abstract: PCT No. PCT/SE95/01089 Sec. 371 Date Apr. 11, 1997 Sec. 102(e) Date Apr. 11, 1997 PCT Filed Sep. 25, 1995 PCT Pub. No. WO96/11852 PCT Pub. Date Apr. 25, 1996A pallet having a plurality of parallel base beams, and a deck joined to the plurality of parallel base beams. The deck includes a web or sheet of material, which is folded to form a deck surface with a plurality of parallel panels adjoining each other, and a plurality of parallel projections on an underside thereof. Each base beam extends upward to contact the underside of the parallel panels, and includes at least one through-recess having a shape which corresponds to a cross-section of a corresponding one of the plurality of parallel projections. The corresponding parallel projection engages the recess thereby forming the pallet with a plurality of spaces to accommodate lifting forks between the plurality of parallel base beams. Lower surfaces of the plurality of parallel projections form lifting surfaces for the lifting forks.
Patent FR-1269903-A (FR)
IPC: D06M15/53
Filed: 1960-09-06
Granted: 1961-08-18
Abstract: Cellulose fibres are treated with an aqueous solution containing not more than 4% sodium hydroxide and then reacted with 0,1-5% ethylene oxide, based on the dry weight of the cellulose. Preferably, 1% to 3% sodium hydroxide solution is used at from 5 DEG -50 DEG C., and less than 3%, preferably about 1% ethylene oxide substitution is effected by reaction at from 20 DEG -90 DEG C. under conditions such that 50% conversion efficiency is attained.  The product is fibrous, exhibits improved whiteness stability on exposure to heat and light, and is substantially insoluble in 5% sodium hydroxide solution.  U.S.A. Specification 2,614,102 is referred to.
Patent GB-536345-A (GB)
Title: Improvements in or relating to firedamp-proof lamps
IPC: F21V25/12
Filed: 1940-01-17
Abstract: 536,345. Electric safety lamps. FRIEMANN & WOLF GES. Jan. 17, 1940, No. 1033. Convention date, Feb. 6, 1939. [Classes 75 (ii) and 75 (iv)] An electric lamp for use where firedamp may be present comprises a tightly enclosed housing of two or more metal jackets separated electrically by layers of vulcanized rubber 2. The outer jacket 1 carries the cables and a screwed ring 7 for retaining a protective grid 8 and a flanged globe 10 while other fittings 11 for carrying current are mounted on the inner jacket 3. The grid 8 is mounted on a ring 9 which screws into the ring 7. The ring 9 is split and provided with end abutments 14, 15. A screw 16 with triangular head 17 screws through the block 15 and bears on block 14. The ring 9 can be opened out by using a box spanner, with a triangular hole, on the head 17.
Patent GB-562163-A (GB)
Title: Chlorination of chromium bearing materials
IPC: C22B1/08
Filed: 1942-01-27
Abstract: 562,163. Chromium chloride. CLEVELAND, F. J. (Pittsburgh Plate Glass Co.). Jan. 27, 1942, No. 1156. [Class 1 (iii)] In the chlorination of chromium ores containing magnesium, a reagent is added to the material which will react with the magnesium to form a compound other than an oxide having a higher melting point than magnesium chloride and minimize sintering. Suitable reagents are fluorine or oxides of sulphur, phosphorus or nitrogen. The process may be conducted in an apparatus comprising a furnace 1 in which a charge of ore and carbon is subjected to the action of chlorine from tuyeres 3 and fiuorine or other agent from tuyere 4. Chromium chloride is condensed in a condenser 7 and iron chloride, if present, in a condenser 8. Specification 533,377 is referred to.
Patent GB-833614-A (GB)
Title: Improvements in ignition devices for internal combustion engines
IPC: F02P3/09
Filed: 1958-01-13
Abstract: 833,614. Ignition systems. COMPAGNIE GENERALE DE TELEGRAPHIE SANS FIL. Jan. 13, 1958 [Jan. 25, 1957], No. 1216/58. Class 7(4) [Also in Group XXXV] An ignition device for internal combustion engines comprises a capacitor 5 and a circuit for charging the same at a retarded rate via a transistor 1; 2, 3 which is periodically made conductive by a biasing pulse synchronized with the rotation of the engine shaft this capacitor being connected to discharge into the ignition coil 10, 12 through a coil 8 having a core 9 which is polarized to reach saturation near the instant when the charge on the capacitor is at its maximum value. The base 3 of the transistor is connected to a pulse supply 6 comprising for instance a small magneto or alternatively by a photo-electric cell preferably of the semi-conductor type associated with a luminous excitation source moving in synchronism with the engine shaft or else by a direct voltage supply associated with a breaker through which this source is connected to the base 3 for a very short-period during each revolution of the engine shaft. The secondary 12 of the ignition coil is connected to a distributer. Between the pulses supplied by the source 6 the transistor becomes non-conductive. The battery 13 charges the capacitor 5 to a potential of -12 volts for instance. The supply 6 then applies a negative voltage pulse on the base 3 of the transistor. The transistor is made conductive and a current can flow through the capacitor 5 and the coil 4. This current induces across the coil 7 a negative voltage of the same order of magnitude as the gating pulse provided by the source 6. The capacitor operates an oscillating discharge through the coil 4. The dimensions of the coil 8 and the polarization of the ferrite core 9 are so selected that this core reaches the satuation point at or near the instant when the voltage across the coil 8 is a maximum. The impedance of the winding 8 suddenly drops at this instant and the capacitor 5 suddenly discharges into the coils 8, 10. This produces the desired ignition spark. The time during which the ignition spark is produced is reduced and it is possible to increase the ignition frequency. In a modification a ferrite tube carrying a longitudinal winding is used the winding being connected in the circuit of Fig. 1 in lieu of the winding 8. The polarization is obtained by a permanent magnet which generates a field parallel to the axis of the tube.
Patent GB-523744-A (GB)
Title: An improved appliance for removing mud or dirt from boots or shoes
IPC: A47L23/22
Filed: 1939-01-13
Abstract: 523,744. Cleaning boots. PERCIVAL, L. K. Jan. 13, 1939, No. 1221. [Classes 19 and 138 (i)] A portable appliance for removing mud or dirt from boots or shoes comprises brushes or the like 7, 11 and a scraping appliance 5, if required, mounted in a slightly elevated position on a stick 1 which rests directly on the ground with a disc 4 to prevent it digging in too deeply. The stick can easily be turned into position for brushing each side of the boot or shoe. The handle 1 provides a support to the person using the cleaning appliance. The device is applicable to a sports seat in which the handle of the -stick forms seat.
Patent GB-227849-A (GB)
Title: An improved electromagnetic percussive tool
IPC: H02K33/18
Filed: 1925-01-15
Abstract: 227,849. Japolsky, N., and Kostenko, M. Jan. 16, 1924, [Convention date]. Percussive hand tools. - The striker of an electricallyactuated percussive tool contains no magnetic material and is traversed by an alternating current so as to reciprocate in a magnetic field produced by a direct current. The striker B, Fig. 13, is connected by flexible conductors B<1> with a source of alternating current and is guided by means of a projection C<1> in the field of the direct-current windings I, II. Springs may be inserted in front of and behind the striker, or a cylinder and piston may be employed behind the striker. Suitable guides may be used in place of the flexible conductors B<1>, or the striker B may itself form the secondary member of an alternating current transformer, as shown in Fig. 8, the primary windings III, IV of the transformer being wound on the same core as the direct current windings I, I<1>, II, II<1>.
Patent GB-675648-A (GB)
Title: Improved centrifugal separator for the continuous separation and discharge of solid matter from a liquid mixture
IPC: E02F3/18
Filed: 1951-01-17
Abstract: 675,648. Centrifugal separators. AKTIEBOLAGET SEPARATOR. Jan. 17, 1951 [Jan. 19, 1950], No. 1303/51. Class 23 The separator continuously separates solids from a liquid mixture, the solids being removed by a paring device 29 and pipe 30 from a chamber without contact with the atmosphere. The separated liquid, passing through an outlet 27, is also prevented from contact with the atmosphere. Liquid seals 37, 23 are used to prevent entry of air. Liquid and solids enter the apparatus through a port 8 and pass through passages 10, 17 to a chamber 13 and separating chamber 18. Solids, with part of the liquid, are discharged through channels 22 and exchangeable nozzles 33 which may be directed to assist in driving the rotor 2. The liquid passes through holes 20 into a chamber 21 and is led through a paring disc 24 to the outlet 27. The disc 24 and a further disc 36 act as liquid seals for the chamber 21, assisted by walls 23, 37, the latter being provided with holes 38 to allow passage of liquid into the chamber between walls 23, 37. This also prevents froth from escaping through the neck 7. A disc 35 is provided to prevent the ingress of liquid from the passages 17 passing into the chamber 28. The apparatus may be used in the separation of yeast-containing liquids, such as wine, and fermented sugar solutions containing yeast.
Patent GB-250997-A (GB)
Title: An improved means for advertising
IPC: G09F11/12
Filed: 1925-01-16
Abstract: 250,997. Preston, C. H. F., and Parkinson, R. H. Jan. 16, 1925. Reel and non-endless web apparatus. - An advertising apparatus comprises a series of travelling frames C moving round a closed track, each carrying two spring rollers G<1>, G<2> and preferably a sign P. Each roller has attached to it one end of a flexible poster web, each of which connects two frames. The sign P passes across the display face when one web is being wound up and another unwound. The mechanism for exposing the webs in turn comprises an endless moving chain F carrying a lug D which engages a projecting pin A<2> on each frame C which has come to, and is held by a catch in, the upper position, and draws it down the display face. After leaving the frame C at the bottom the lug D raises a bar M furnished with guide wheels O. The bar M carries pawls N which take under the pins A<2> and move the frames C forward, a rack and pawl &c. holding them in position. When a frame is descending the display face the displayed web is wound on a roller G<2>, and the new web off a roller G<1>, the other two rollers being held stationary by a pawl or pinion. The web is transferred from roller G<2> to roller G<1> during the travel of the frames C up the back of the apparatus, either by rack and pinion gearing, or by a difference in the tensions of the spring rollers. According to the Provisional Specification electric lamps may be arranged on rotatable frames acting as a border, and one of the rollers G', G<2> may be replaced by a bar.
Patent GB-1091938-A (GB)
Title: Improvements in or relating to flexible harrows
IPC: A01B19/08
Filed: 1966-01-12
Abstract: 1,091,938. Agricultural implements. W. AITKENHEAD. Oct. 4, 1966 [Jan. 12, 1966], No. 1389/66. Heading A1B. A flexible harrow of the type comprising a plurality of interlinked elements each produced by bending a length of steel rod to provide two spaced eyes B in a generally horizontal plane between two mutually divergent arms A each bent into a generally vertical loop E and then continued more or less at right angles to itself to form a tine or having secured thereto a separate tine D is characterized in that some or all of the elements are reinforced by a strut F which extends between the generally vertical loops E.
Patent GB-813007-A (GB)
Title: Improvements in silk screen printing
Inventor: NOBLE GEORGE
IPC: B41F15/36
Filed: 1957-01-14
Abstract: 813,007. Stretching fabrics. SCREEN PROCESS SUPPLIES Ltd. Jan. 8, 1958 [Jan. 14, 1957], No. 1426/57. Class 42 (1). [Also in Group XVI] Apparatus for stretching material to a silk screen printing frame comprises means for releasably securing a member in rotatable manner parallel to one side of the frame, means for releasably securing the screen printing material to the member and means for rotating the member while the material is secured thereto. To each of the sides 1b, 1c of the screen frame 1, Figs. 1 and 2, there is secured by means of a U-shaped abutment member 7 and a screw 8, a L-section clamp 3 having a rotatable bearing 4 for receiving a square section bar 5, the bearings having ratchets to prevent rotation of the bar counter-clockwise in Fig. 2. The screen 2 is secured to the side la of the frame and the free edge of the screen is passed round and secured to the bar 5 by a U-section channel member 9. The bar is then rotated by a handle 6. The screen is then secured to the side 1c and the clamps to the sides 1a, 1d, and the operation repeated in the transverse direction, using a shorter member 9.
Patent GB-391913-A (GB)
Title: Improvements in cylinder lock mechanism
IPC: E05B27/00
Filed: 1932-01-19
Abstract: 391,913. Locks. REYNOLDS, T. 0., Neachell Works, Moseley Village, Willenhall, and BURROWS, G. H., 62, Ruskin Street, West Bromwich, both in Staffordshire. Jan. 19, 1932, No. 1565. [Class 44.] In a lock of the kind comprising a number of wards 1 fixed in a cylindrical casing 2 and spaced apart by distance washers 3, each ward having a semicircular aperture 1a allowing rotation of a non-slotted part of the key 4, and a slot 1b which holds the key against rotation unless, a slot in the key registers with the ward, a rotatable barrel 18 is provided in the outer end of the casing, the barrel having a reduced portion bearing in an aperture in the rose 15, which is preferably integral with the casing 2. The barrel has a slot 17 shaped to allow insertion and removal of the key when the slot registers with a notch 19 in the rose. The barrel is held with the slot and notch in register by a spring plunger 14 which is pressed back to release the barrel for rotation by a projection 20 on the key which enters through notch 19. The wards are held against rotation by ribs 6 in the casing engaging notches in the wards. The inner end of the casing is closed by an apertured disc 24 riveted in place. Adjacent disc 24 is a rotatable disc 12 with a cruciform aperture, two limbs of which receive the T-head 10 of a bar 9 which serves to operate the bolt, not shown, and the other two limbs are engaged by the inner end of the key, which is notched to straddle the part 10. A spring washer 26 is interposed between disc 12 and the adjacent spacing washer. Within the rose 15 are attachment lugs 23 tapped to receive affixing screws inserted from the opposite face of the door. The casing may be die-cast, or built up from washers, projections on each washer engaging recesses on the face of the adjacent washer.