baber/WOPTO huggingface dataset:
Patent CA-2997809-A1 (CA)
Inventor: DURUM SCOTT
IPC: C07K16/28
Filed: 2016-10-07
Abstract: Antibodies and antigen binding fragments that specifically bind to IL-7Ra are disclosed. Nucleic acids encoding the antibodies and antigen binding fragments, and vectors including the nucleic acid molecules are also provided. Methods for detecting a ca cancer or a cell that expresses IL-7Ra using the antibodies and antigen binding fragments are disclosed, as is the use of the antibodies and antigen binding fragments to prevent and/or treat a subject with a cancer that expresses IL-7Ra, such as acute lymphoblastic leukemia.
Patent CA-2997949-A1 (CA)
Title: Procedes de traitement de troubles et d'affections cutanes en utilisant des haptenes
Inventor: CAUWENBERGH GERARD
IPC: A61K31/12
Filed: 2016-09-09
Abstract: L'invention concerne l'utilisation d'approches thérapeutiques pour traiter divers troubles et affections cutanés. En particulier, l'invention concerne le traitement de cancers cutanés et de la métastase cutanée de tumeurs solides, ainsi que l'élimination de tatouages, au moyen d'un haptène. L'invention concerne diverses formulations topiques comprenant un haptène pour le traitement de ces troubles et affections cutanés.
Patent CA-2997989-A1 (CA)
Inventor: WOODWORTH NATHAN
IPC: A01G3/00
Filed: 2018-03-12
Abstract: A plant trimming apparatus for trimming plant material is provided. The apparatus comprises a housing comprising an interior and a cylindrical wall and a plurality of openings through the cylindrical wall. A  cutting wire in the interior of the housing passes by the openings, wherein the plant material passing through the plurality of openings is trimmed by the cutting wire. The apparatus further comprises a spindle rotationally attached to the housing, the cutting wire attached to the spindle via a member, such that the cutting wire traces a cylinder when the spindle rotates, and an outlet in the housing for removing trimmed plant material.
Patent CA-2999485-A1 (CA)
Title: Procedes, systemes et produits de programme informatique pour determiner des distances d'objet et des dimensions de cible au moyen d'emetteurs de lumiere
Inventor: CHEN CHENG
IPC: A61B3/08
Filed: 2016-09-21
Abstract: La présente invention concerne des procédés, des systèmes et des produits de programmes informatiques pour déterminer des paramètres pendant une procédure chirurgicale. Une pluralité de motifs sont projetés sur un plan d'objet associé à une cible devant être soumise à imagerie. La pluralité de motifs sont manipulés de sorte que la pluralité de motifs se chevauchent au niveau d'un point commun indiquant une distance d'objet appropriée depuis la cible devant être soumise à imagerie.
Patent CA-3000064-A1 (CA)
Inventor: SANCHEZ GOMEZ SANTIAGO
IPC: B28D7/00
Filed: 2016-07-19
Abstract: The invention relates to a ceramic cutter having liquid-cooling by immersion of the cutting disc, comprising: a support frame (1); an electric motor (2) for actuating a cutting disc (3); a tray (4) containing water for cooling the cutting disc (3) by immersion; an auxiliary water tank (6), which is removable, disposed above the cooling tray (3) and provided with a gravity-driven water outlet (61, 62) for discharging water into the cooling tray (3), said outlet being accommodated in the tray (3) and being disposed at a height corresponding to a predetermined level of the water for cooling the cutting disc (3) by immersion.
Patent CA-3001103-A1 (CA)
Inventor: RICCI GIOVANNI
IPC: C08F36/06
Filed: 2016-12-23
Abstract: Process for the preparation of (co)polymers of conjugated dienes comprising polymerizing at least one conjugated diene in the presence of a catalytic system comprising at least one vanadium bis-imine complex having the general formula (I): <DIG>
Patent CA-3004191-A1 (CA)
Title: Timbres transdermiques
Inventor: WING SING TSANG RICKY
IPC: A61K9/70
Filed: 2016-11-22
Abstract: La présente invention concerne un timbre transdermique comprenant une formulation pharmaceutique, la formulation comprenant de la ropivacaïne ou un opioïde, un adhésif pharmaceutiquement acceptable comprenant jusqu'à 75 % en poids de silicone ou de polyisobutylène et entre 5 et 20 % en poids d'un mélange d'excipients. La présente invention concerne également des procédés de préparation d'une telle formulation pharmaceutique, ainsi que l'utilisation d'un tel timbre transdermique dans le traitement de la douleur (par exemple, la douleur nociceptive et/ou neuropathique).
Patent CA-3004450-A1 (CA)
Inventor: STICE STEVEN L
IPC: A61K35/30
Filed: 2016-11-16
Abstract: L'invention concerne des vésicules extracellulaires (VE) neurales et des procédés d'utilisation de ces VE dans le traitement d'une lésion de la moelle épinière, d'un accident vasculaire cérébral, d'un traumatisme craniocérébral et de maladies neurodégénératives.
Patent CA-3006557-A1 (CA)
Inventor: KNOENER CRAIG STEVEN
IPC: B23K9/095
Filed: 2016-12-13
Abstract: Ref. No. 66288-CA ABSTRACT The present disclosure generally relates to systems and methods for setting welding parameters. Provided is a welding system with an interface to receive three inputs;  the first relating to a parameter of power delivered to a welding torch from a welding power supply, the second relating to a rate of advancement of an electrode delivered to the torch from a wire feeder, and the third relating to whether the power and the rate of advancement of the electrode are automatically set. A color display device displays the power and rate of advancement of the electrode. The welding system also includes control circuitry to adjust and display the power and rate of advancement based at least in part on a selected diameter setting for the electrode and a selected material thickness for a work piece when the third input element is activated, with control based on the adjustment of the parameter of power and the rate of advancement.
Patent CA-3008023-A1 (CA)
Inventor: RUMINSKI PETER G
IPC: A61K31/44
Filed: 2016-12-30
Abstract: The present disclosure provides pharmaceutical agents of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods of using the pharmaceutical agents for the treatment of a variety of diseases and disorders are also provided.
Patent CA-3008921-A1 (CA)
Inventor: YU JINZE
IPC: B23K26/382
Filed: 2017-07-28
Abstract: A precise release hole making apparatus for a sustained release package of a grape preservative, comprising a machine frame (1), a winding and unwinding mechanical transmission mechanism (2), a pulse laser generator (3), a laser tube cooling system (4), and a smoke and paper scrap sucking apparatus (5). The winding and unwinding mechanical transmission mechanism (2) is mounted on the machine frame (1). The pulse laser generator (3) is vertically mounted on the machine frame (1) and perpendicular to a frame platform surface. The laser tube cooling system (4) is a closed cooling water circulation system for cooling a laser tube to ensure normal operation thereof. The smoke and paper scrap sucking apparatus (5) uses a vacuum pump and a pipeline to suck away smoke and paper scraps generated by laser hole making to keep clean the environment and a hole-make working surface. The apparatus greatly reduces costs by omitting a manual hole-drilling procedure before the use of a preservative, greatly improves the controllable release property of a grape preservative SO2, and improves the grape preservation quality and reliability.
Patent CA-3009923-A1 (CA)
Inventor: REEVELL TONY
IPC: A24F40/60
Filed: 2017-02-17
Abstract: There is provided a method of operating an electrically operated aerosol generating system (100) comprising a storage portion (113) for storing an aerosol forming substrate (115), at least one heating element (119) for heating the aerosol forming substrate, a sensor (111) for detecting an activation of the system, a clock, and electric circuitry (109) connected to the sensor. The method includes measuring a usage parameter (T2, T4, C1), comparing the measured usage parameter to a threshold value(T2mode, T4mode, C2), determining a usage profile of the system based on the comparison, repeating at different times of day the steps of initiating a monitoring procedure, measuring a usage parameter, comparing the measured usage parameter, and determining a usage profile, to determine the usage profile at different times of day, and selecting an operating mode of the system based on the determined usage profile associated with the current time of day. There is also provided an electrically operated aerosol generating system and a further method of operating in which the usage profile is determined by ending a monitoring procedure when the measured usage parameter exceeds a threshold value and comparing the duration of the monitoring procedure to a threshold duration to determine the usage profile.
Patent CA-3013679-A1 (CA)
Inventor: WOOD DENNIS
IPC: F16M11/42
Filed: 2018-08-09
Abstract: A camera slider assembly for supporting a camera thereon including a frame with a pair of rails and a carriage body that rolls longitudinally along the rails upon which a camera can be supported. A flywheel of conductive is supported on the frame and operatively connected to the carriage body for rotation about a flywheel axis responsive to displacement of the carriage body along the rails. A magnet movable on the frame relative to the flywheel acts as an eddy current brake to apply a controllable drag force to the flywheel rotation. The rails of the frame are indexed relative to one another using cross members having indexing surfaces, and clamping fasteners cooperating with ramped surfaces to urge the rails against the corresponding indexing surfaces as the clamping fasteners tighten the rails against the ramped surfaces.
Patent CA-3014025-A1 (CA)
Title: Outil de collecte de debris de fond de trou ayant une soupape amelioree
Inventor: HAUGLAND LASSE
IPC: E21B27/00
Filed: 2017-02-21
Abstract: L'invention concerne un outil de fond de trou (100) pour collecter des débris dans un puits de pétrole. L'outil de fond de trou (100) comprend : i) un logement (120) relié à une chambre de collecte (130-1, 130-2) pour recevoir des débris, le logement (120) ayant une ouverture (105) pour collecter les débris provenant du puits de pétrole, l'ouverture (105) étant en communication fluidique avec la chambre de collecte (130-1, 130-2) par l'intermédiaire du logement (120) ; ii) un arbre rotatif (110b) avec des pales de transport (119) disposées dans le logement (120) et s'étendant de l'ouverture (105) à la chambre de collecte (130-1, 130-2), l'arbre rotatif (110b) étant configuré pour transporter les débris de l'ouverture (105) à la chambre de collecte (130-1, 130-2) en utilisation fonctionnelle ; iii) une zone annulaire (121) définie entre l'arbre rotatif (110b) et une paroi interne du logement (120) ; et iv) une soupape (125) configurée pour maintenir les débris dans la chambre de collecte (130-1, 130-2), la soupape (125) étant située dans le logement (120) entre l'ouverture (105) et la chambre de collecte (130-1, 130-2), la soupape (125) comprenant en outre un élément joint d'étanchéité (125s) avec une partie mobile (125sm) montée dans la zone annulaire (121) et autour de l'arbre rotatif (110b), la soupape (125) étant ouverte lorsque la partie mobile (125sm) se déplace vers la chambre de collecte (130-1, 130-2), la soupape (125) étant configurée de telle sorte que la partie mobile (125sm) de l'élément joint d'étanchéité (125s) est uniquement mobile dans la direction vers la chambre de collecte (130-1, 130-2) lorsqu'il est fermé. L'outil de fond de trou de l'invention fournit une soupape, qui est ouverte facilement, nécessitant une très petite force, tout en fournissant en même temps un très bon effet d'étanchéité lorsque l'élément joint d'étanchéité est fermé.
Patent CA-3015419-A1 (CA)
Title: Weeping tile flapper valve
Inventor: ZHANG SHIJIE
IPC: F16K1/20
Filed: 2018-08-27
Abstract: A flapper valve (backwater valve) that is made of plastic and has a handle is used to drain weeping tile. The invention is useful in that the flapper valve can replace existing metal flappers that are present in weeping tiles installed prior to mid 1980's, and avoid basement flood caused by existing metal flappers that tend to rust and have no handle.
Patent CA-3015660-A1 (CA)
Inventor: HSU JER-YUAN
IPC: C07K14/475
Filed: 2017-03-03
Abstract: The present disclosure provides a protein complex, including a three-dimensional structure of the protein complex, that plays a role in regulation of body weight. In addition, the protein complex and components thereof, including three-dimensional structures thereof, find use in identifying agents that can be used to control body weight.
Patent CA-3016326-A1 (CA)
Title: Method for producing particles
Inventor: ONOUE SATOMI
IPC: A61K9/16
Filed: 2017-03-02
Abstract: A method for producing particles, the method including: applying vibration to a liquid including a physiologically active substance and included in a liquid-column resonance liquid-chamber to form a standing wave based on liquid column resonance, to thereby discharge the liquid from at least one discharging port, which is formed in an amplitude direction of the standing wave, to at least one region corresponding to at least one anti-node of the standing wave; and drying the liquid discharged, to thereby form particles.
Patent CA-3016444-A1 (CA)
Inventor: Guadagnoli Lucian Michael
IPC: B25F1/02
Filed: 2017-03-02
Abstract: A hand tool which can be a multibit fastener driver with an in-handle bit storage system. A fastener driver which can have bit storage system which can have a bypass angle which provide an exit path for a bit being removed from storage which is free of intersection with obstacles and achieves efficient removal of bits from bit storage chambers. A bit storage system which can have one or more bit retainers and/or one or more bit grips which reversibly maintain a bit in storage when the fastener driver is in any orientation. Methods, means and processes for effective and efficient bit storage and release of bits for use by an operator.
Patent CA-3016934-A1 (CA)
Inventor: BOUDON STEPHANIE
IPC: A61K8/67
Filed: 2018-09-07
Abstract: The present invention relates to the use of a composition for obtaining shiny, soft and elastic, smooth, moisturized and vital hair. The same composition is also used in a method for obtaining shiny hair.
Patent CA-3017842-A1 (CA)
Inventor: SCHNEIDER NORA
IPC: A61P25/00
Filed: 2017-03-30
Abstract: The present invention relates to a composition comprising choline for use in promoting, supporting or optimizing one or more of the following: (i) de novo myelination; (ii) brain structure; (iii) brain connectivity; (iv) intellectual potential; (v) cognitive potential; (vi) learning potential; and (vii) cognitive function; in an offspring of a female subject, wherein said composition is for administration to the female subject.
Patent CA-3019593-A1 (CA)
Title: Cosmetic material compositions
Inventor: CARLSON LAWRENCE
IPC: A61Q19/08
Filed: 2017-03-31
Abstract: A composition comprising: at least one compound of the chemical structure:[Formula should be inserted here] wherein x is and odd integer =3; y is an integer between 1 and 20; and Z is one of a monoatomic ion from Groups 14 through 17 having a charge value between -1 and -3 or a polyatomic ion having a charge between -1 and -3; or Z - Hx'Ox'-y' wherein x' is and integer greater than 3 y' is an integer less than x'; and Z' is one of a monoatomic cation, a polyatomic ion or a cationic complex; and at least one of a humectant emollient or carrier.
Patent CA-3022737-A1 (CA)
Inventor: VANGBERG-BRINKMANN KATHARINA
IPC: A47H1/13
Filed: 2018-10-31
Abstract: The mounting element (101) comprises: -    an elongate mounting member (102) having a first end (102.1), a second end (102.2), and a guide surface, -    an extension mechanism (104) arranged at the first end (102.1) and operable between: i) a retracted state, and ii) an extended state, a telescopic extender (1) arranged at the second end (102.2) and operable between a retracted configuration and an extended configuration. The telescopic extender (i) comprises: a slidable body to slide along the guide surface so as to lengthen the mounting element (101), and a locking member configured: i) to allow the slidable body to slide in the first translation direction, and ii) to prevent the slidable body from sliding in a second translation direction opposite the first translation direction.
Patent CA-3026286-A1 (CA)
Inventor: EDWARDS JOSHUA
IPC: G06T7/90
Filed: 2018-12-03
Abstract: A transaction card construction and computer-implemented methods for a transaction card are described. The transaction card has vector-formatted visible information applied by a laser machining system. In some embodiments, systems and methods are disclosed for enabling the sourcing of visible information using a scalable vector format. The systems and methods may receive a request to add visible information to a transaction card and capture an image of the visible information. The systems and methods may capture data representing the image. The systems and methods may also determine an ambient color saturation of the image. Further, systems and methods may translate the image based on the ambient color saturation of the image. The systems and methods may also map the translated image to a bounding box and convert the mapped image into vector format. In addition, the systems and methods may provide the converted image to a laser machining system.
Patent CA-3028183-A1 (CA)
Inventor: SANG RUI
IPC: C07F15/00
Filed: 2018-12-19
Abstract: Il est décrit un procédé pour lhydroxycarbonylation à Pd catalysé de diisobutylène : rapport acide sulfurique-ligand.
Patent CA-3029155-A1 (CA)
Inventor: NAKANO TAKUMA
IPC: A24D3/17
Filed: 2017-06-28
Abstract: A flavor inhaler that comprises: a tubular holder that extends from a mouthpiece end to a tip end; a combustion-type heat source that is provided at the tip end, contains activated carbon, and is loaded with a first flavoring; and a flavor source that is held inside the holder and is loaded with a second flavoring. The first flavoring includes at least one compound selected from the group that consists of anethole, 2-pinene, ß-citronellol, linalyl acetate, limonene, anisaldehyde, 4-terpineol, 2-ß-pinene, jasmone, sabinene, linalool, 1,8-cineole, phenethyl alcohol, and myristicin. The second flavoring includes at least one compound selected from the group that consists of a-terpinene, ?-terpinene, nerol, geraniol, and decanal.
Patent CA-3029325-A1 (CA)
Inventor: JAGER GERNOT
IPC: C07C209/68
Filed: 2017-06-27
Abstract: The invention relates to a method for producing aniline or products that are obtained by further chemical reaction of aniline (aniline derivatives), involving decarboxylation of aminobenzoic acid, particularly ortho-aminobenzoic acid, in which one portion of the previously formed crude aniline is recirculated in the decarboxylation step. The aminobenzoic acid is obtained enzymatically or chemically, preferably enzymatically.
Patent CA-3030350-A1 (CA)
Inventor: BARRETT STEPHEN JOHN
IPC: H04W4/08
Filed: 2017-07-10
Abstract: In some examples, a first push-to-talk (PTT) client that has access to a wide area network (WAN) performs distributed control for a PTT session in conjunction with distributed control for the PTT session performed by another PTT client in the PTT session, the distributed control by the first PTT client performed without use of any PTT server.
Patent CA-3031183-A1 (CA)
Title: Vesicule extracellulaire comprenant une proteine de fusion ayant une capacite de liaison de fc
Inventor: WIKLANDER Oscar
IPC: A61K39/395
Filed: 2017-07-21
Abstract: La présente invention concerne des agents thérapeutiques à base de vésicules extracellulaires (EV), les EV étant enrobées de protéines contenant des domaines Fc (tels que des anticorps) pour, entre autres, des applications de ciblage et thérapeutiques. L'enrobage des EV est obtenu au moyen de l'ingénierie des protéines des polypeptides EV de l'invention. Par conséquent, l'invention concerne des procédés d'enrobage d'EV, des EV en tant que tels, ainsi que des compositions pharmaceutiques et des applications médicales de telles EV enrobées de protéines contenant Fc.
Patent CA-3032252-A1 (CA)
Inventor: DEORE BHAVANA
IPC: C09D11/52
Filed: 2017-07-19
Abstract: An ink contains an admixture of a copper nanoparticle, a copper precursor molecule (e.g. a copper-aminediol complex), and a polymeric binder, the polymeric binder containing a polyester, polyimide, polyether imide or any mixture thereof having surface 5 functional groups that render the polymeric binder compatible with and/or soluble in a diol. The ink may be deposited on a substrate providing a trace that is conductive and directly solderable and has better mechanical strength than copper inks containing other types of polymeric binders.
Patent CA-3032565-A1 (CA)
Title: Control channel bandwidth determination
Inventor: CHEN WANSHI
IPC: H04L5/00
Filed: 2017-08-11
Abstract: Aspects of the disclosure relate to determination of bandwidth, frequencies, or a set one or more of subbands that carries a downlink control channel. In some examples, a set of one or more subbands that carries a downlink control channel may be determined based on a function of a predetermined reference resource location. The predetermined reference resource location may be a set of one or more subbands that carries one or more synchronization signals and a broadcast channel.
Patent CA-3034124-A1 (CA)
Title: Peptides de fusion avec des antigenes lies a des fragments courts de chaine invariante (cd74)
Inventor: BASSI MARIA ROSARIA
IPC: C07K14/705
Filed: 2017-08-23
Abstract: La présente invention concerne, entre autres, une protéine de fusion comprenant un polypeptide, le polypeptide étant constitué d'un fragment de chaîne invariante qui est lié de manière fonctionnelle à une séquence antigénique et le fragment de chaîne invariante étant constitué d'une partie des résidus 17-97 de SEQ ID NO: 1, où la partie comprend au moins 5 résidus contigus des résidus 77-92 de SEQ ID NO : 1.
Patent CA-3034259-A1 (CA)
Inventor: SETTLEMAN JEFF
IPC: A61K31/4523
Filed: 2017-08-22
Abstract: The subject matter described herein is directed to compositions comprising a MEK inhibitor, or a pharmaceutically acceptable salt thereof, and a multi-kinase inhibitor that targets PDGFRa, S6 and STAT3 or a pharmaceutically acceptable salt thereof, and their use in treating pancreatic cancer. In another aspect, disclosed herein are methods of treating pancreatic cancer by administering a MEK inhibitor, or a pharmaceutically acceptable salt thereof, and a multi-kinase inhibitor, or a pharmaceutically acceptable salt thereof. In another aspect, the combination of cobimetinib, or a pharmaceutically acceptable salt thereof, and ponatinib or a pharmaceutically acceptable salt thereof is administered in a composition or the combination is administered separately to treat pancreatic cancer.
Patent CA-3034559-A1 (CA)
Inventor: MANZ FLORIAN
IPC: B32B17/10
Filed: 2017-07-25
Abstract: The invention relates to a composite pane (1) for a head-up display, at least comprising a first pane (1.1) and a second pane (1.2), which are joined to each other via a composite layer (2, 3, 4), and a transparent, electrically conductive coating (10), wherein the composite layer (2, 3, 4) has a first thermoplastic film (2), a polyester film (3) and a second thermoplastic film (4), having a ratio of the thicknesses of the second thermoplastic film to the first thermoplastic film of 1.5:1 to 20:1.