baber/WOPTO huggingface dataset:
Patent CA-3069533-A1 (CA)
Inventor: PRESTRELSKI STEVEN
IPC: A61P3/08
Filed: 2018-07-14
Abstract: A method of treating congenital hyperinsulinism in a subject is disclosed. The method can include parenterally administering to the subject a first composition comprising a glucagon, a glucagon analogue, or a salt form of either thereof, and optionally administering to the subject a second composition comprising glucose, a glucose analogue, or a salt form of either thereof, wherein administration of the first composition sufficiently increases blood glucose level in the subject such that the second composition is not administered or the second composition is administered at a glucose infusion rate (GIR) of less than 8 mg/(kg*min).
Patent CA-3069583-A1 (CA)
Title: Injection device with flexible dose selection
Inventor: KEITEL JOACHIM
IPC: A61M5/50
Filed: 2017-09-25
Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a coupling assembly that is rotationally engaged with a snap element such that the snap element can rotate relative to the coupling assembly during both dose setting and dose delivery.
Patent CA-3070442-A1 (CA)
Title: Methods of protecting vascular integrity induced by targeted radiation therapy
Inventor: EICHENBAUM GARY
IPC: A61K38/22
Filed: 2018-07-26
Abstract: Methods of protecting vascular integrity in a subject exposed to a targeted radiation therapy are described. In particular, an effective amount of a thrombopoietin (TPO) mimetic, such as TPOm, is used to protect vascular integrity following the radiation therapy.
Patent CA-3071733-A1 (CA)
Inventor: ASH SIMON CHRISTOPHER
IPC: E21B23/10
Filed: 2020-02-06
Abstract: A downhole tool connection comprises (i) a tool (10) intended for downhole use and including a connection section (12) protruding therefrom in use in an uphole direction, the connection section (12) supporting two or more first connectors (16, 17, 18, 19, 21, 22, 23, 24) that are spaced from one another and operatively connected to the tool (10); and (ii) a cable carrier (26) that is moveable in an in use downhole direction towards the connection section (12). The cable carrier (26) supports (a) one or more cables (27) and (b) two or more second connectors (28, 29, 31, 32, 33, 34, 36, 37) that are spaced from one another and operatively connected to at least one said cable (27). Pairs of the first and second connectors are mutually connectable, on movement of the cable carrier (26) towards the tool connection section (12) so as to increase the proximity of the connectors of the pairs, in a manner effecting electrical transmission between the connectors of each pair, wherein at least one pair of the connectors connects inductively and at least one pair of the connectors connects conductively.
Patent CA-3075239-A1 (CA)
Inventor: KLOOSTER VAN DER
IPC: B29C63/10
Filed: 2018-07-16
Abstract: A tape application device (1) comprises a tube holder (9), a roll retainer (11), guide means (35) for guiding a tape (3) from the inside (7a) of a roll (7) to the outside of a tube (5) and displacement means for rotating around an imaginary axis and translating in the direction of the imaginary axis the tube holder, roll retainer and guide means relative to each other, such that the tape is pulled out of the roll on the inside and is helically wound on the outside of the tube. The roll retainer (11) has support means (26) which support the roll only on the outside, which support means are formed by suction cups (27). The guide means (35) are formed by a resilient helical tape guide (37) which, during operation, resiliently pushes with one end (37a) against the inside (7a) of the roll (7) and with the other end (7b) is present close to the tube (5).
Patent CA-3075333-A1 (CA)
Title: Plant health compositions comprising a water-soluble pesticide and a water-insoluble agrochemical
Inventor: ZHANG JUNHUA
IPC: A01N25/30
Filed: 2011-03-14
Abstract: A suspension concentrate composition comprising water and at least one water-soluble pesticide in solution therein, a surfactant component comprising at least one surfactant, and at least one water- insoluble agrochemical. The weight ratio of the surfactant component to the water-insoluble agrochemical is from 1:1 to 5:1. A first portion of the water-insoluble agrochemical comprising at least 10% by weight of the water-insoluble agrochemical is present as a solute in the surfactant component and a second portion of the water-insoluble agrochemical is present as a solid particulate. The water soluble pesticide concentration is at least 400 grams active equivalent per liter of the concentrate composition.
Patent CA-3076880-A1 (CA)
Title: A laser
Inventor: LAMB ROBERT
IPC: H01S3/08
Filed: 2018-11-02
Abstract: The laser has a housing comprised from a block of glass-ceramic. The block is machined (or otherwise formed) to define one or more channels that act as a waveguide in two dimensions for light within the laser resonator. The channels extend between cavities also formed within the block which retain optical components of the laser, e.g. one or more of the gain medium, cavity mirrors, intermediate reflectors etc. The positioning, shape and size of each cavity is bespoke for the optical component it holds in order that each optical component is retained in optical alignment rigidly against the sides of the cavity.
Patent CA-3080677-A1 (CA)
Inventor: VENKATESHAPPA CHANDREGOWDA
IPC: C07D401/14
Filed: 2018-11-06
Abstract: The compounds of Formula Ib, Formula Ia, and Formula I are described herein along with their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof. The process of preparation of the compounds of Formula Ib, Formula Ia, and Formula I is also described. The compounds described herein, their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof are 2-(benzyloxy)pyrimidine derivatives that are inhibitors of PD-1/PD-L1 activation.
Patent CA-3080772-A1 (CA)
Inventor: CROUCH JONATHAN
IPC: H02M7/00
Filed: 2014-02-10
Abstract: An arm assembly (16) is provided. The arm assembly (16) includes a heat exchanger assembly (30), a plurality of electrical components (50) thermally coupled to the heat exchanger assembly (30), and a number of electrical buses (70). Each electrical component (50) is coupled to, and in electrical communication with, one electrical bus (70). A sealing compound (100) is then applied to each electrical bus (70) and to a limited number of the electrical components (50).
Patent CA-3087376-A1 (CA)
Inventor: NIEMZCYK ANDREW
IPC: E02D3/08
Filed: 2019-01-08
Abstract: A device and method for loosening compacted soil, a plurality of tubular devices made from a resiliently compressible material having a hollow hub with a series of radially and circumferentially curving blades extending from the hub, a plurality of devices arranged in an array in soil to cause loosening of the soil as it seasonally expands and contracts and causes compression and subsequent expansion of the devices which in turn loosens the soil sufficiently to aerate the soil.
Patent CA-3087602-A1 (CA)
Title: Response message processing method, apparatus and storage mediumm
Inventor: LIN YANAN
IPC: H04W72/12
Filed: 2018-03-06
Abstract: Disclosed by the present invention is a response information processing method, comprising: a network device determines whether a user equipment sends the response information corresponding to the target data, and obtains the determination result; sending an instruction signaling carrying the determination result to the user equipment; and the user equipment determines, on the basis of the instruction signaling sent by the network device, whether to send the response information corresponding to the target data. Further disclosed are another response information processing method, a network device, a user equipment and a storage medium.
Patent CA-3089546-A1 (CA)
Inventor: BERTOLOTTI UMBERTO
IPC: B01D35/06
Filed: 2019-02-06
Abstract: The present invention relates to a device (1) for filtering a fluid circulating in a plumbing and heating system, said device comprising a body (2) which defines therewithin a filtration chamber (3) that is intended to have a fluid to be subjected to filtration pass through it. The body is provided with a first inlet/outlet opening (10), a second inlet/outlet opening (20) and a third inlet/outlet opening (30): each one of them sets the filtration chamber (3) in communication with the outside of the device and is associable with a line of the system so as to receive therefrom, or to send thereto, fluid entering, or exiting from, said body of the device. The device operates a passage of fluid through the filtration chamber (3), in a selective manner according to a plurality of operative configurations, from one opening among said first inlet/outlet opening (10), second inlet/outlet opening (20) and third inlet/outlet opening (30) to another opening among said first inlet/outlet opening (10), second inlet/outlet opening (20) and third inlet/outlet opening (30). The device further comprises: filtering members (40) that are housed inside the filtration chamber (3) and operatively interposed between the inlet/outlet openings to carry out filtering of the fluid passing through the filtration chamber; a flow-directing insert (70) that is housed inside the filtration chamber (3) and configured to channel the fluid passing through the filtration chamber, in each one of the operative configurations, so that the fluid passes at least partially through the filtering members (40).
Patent CA-3090733-A1 (CA)
Inventor: GNAM HANS-JURGEN
IPC: C08F6/12
Filed: 2019-02-07
Abstract: The invention relates to an extruder (30) comprising a housing (31), a first material inlet (32) for a mixture (46) at least consisting of a solvent and a dissolved medium, a material outlet (33), a screw (35), a screw drive (34), and at least one distillation region (36a-d) between the inlet (32) and the outlet (33), which allows an outflow of solvent, and a discharge line (43-45) for the solvent.
Patent CA-3096482-A1 (CA)
Inventor: BETTLE GRISCOM
IPC: A61K35/60
Filed: 2019-04-12
Abstract: L'invention concerne une composition pharmaceutique topique anhydre et homogène destinée au traitement de troubles de la peau et de plaies, ladite composition comportant de l'huile de foie de morue, de l'huile de chanvre, de la monolaurine, des triglycérides à chaîne moyenne ("MCT"), des acides gras libres, du sel de mer et une huile végétale sélectionnée dans le groupe constitué par le concentré d'huile de palme rouge, l'huile de noix de coco et l'huile de palme rouge, et une combinaison de celles-ci, ainsi que du collagène de poisson, du palmitate d'ascorbyle, un agent épaississant tel que de la cire d'abeille, un concentré de palme rouge et un ester de cétyle, éventuellement.
Patent CA-3096827-A1 (CA)
Title: Method and device for dynamic and seamless link selection
Inventor: BHARTIA APURV
IPC: H04W92/20
Filed: 2019-04-09
Abstract: A disclosed method is performed at an access point. The method includes receiving a request message from a client device, where the request message includes a request for an allocation of a wireless channel for the client device from the access point. The method further includes exchanging candidate and load information with a plurality of other access points. The method additionally includes selecting a preferred access point from the access point and the plurality of other access points based on the candidate and load information exchanged with the plurality of other access points. The method also includes facilitating the allocation of the wireless channel for the client device from the preferred access point.
Patent CA-3097874-A1 (CA)
Inventor: MCGOVERN DERMOT P
IPC: G01N33/50
Filed: 2019-04-24
Abstract: The present disclosure describes methods, devices and systems of diagnosing, prognosing, and treating subjects with moderate to severe forms of Crohn's disease (CD) that is characterized by stricturing and internal penetrating disease phenotypes. Also described are methods and kits for characterizing a subtype of CD, and identifying a subject as being suitable for a therapy to treat the CD.
Patent CA-3099063-A1 (CA)
Title: Systeme integre de fond de puits a plusieurs sous-systemes de telemetrie
Inventor: LOGAN AARON W
IPC: E21B44/00
Filed: 2014-02-25
Abstract: Abrégé de la divulgation : Un système de fond de puits comporte plusieurs sous-systèmes de télémétrie et un système de commande configurés pour obtenir de l'information auprès d'au moins un capteur et pour transmettre cette information à au moins un des systèmes de la pluralité des sous-systèmes de télémétrie. La configuration d'un tel contrôleur peut être modifiée de façon à changer d'information transmise dans un système de télémétrie donné et à changer la façon dont l'information doit être transmise dans le système de télémétrie considéré. Date Recue/Date Received 2020-11-12
Patent CA-3099096-A1 (CA)
Inventor: LOH YINCE
IPC: A61B5/026
Filed: 2018-06-07
Abstract: Apparatus and methods for diagnosing conditions consistent with the presence of cranial blood vessel blockage and large vessel occlusions (LVO's) using the framework of a small head-harness that is transportable, field-expedient, and durable, A single pulse set using ultrasonic or near- infrared energy is broadcast into a patient's brain allowing the apparatus to perform an area scan of the brain and detect and decipher cranial blood vessel blockage and LVO signal patterns. The interpretation of the pattern lies within the internal programming which produces a binary signal as to whether an LVO is suspected or not.
Patent CA-3099853-A1 (CA)
Inventor: LU CHEN
IPC: D21H17/25
Filed: 2018-05-14
Abstract: The present invention relates to a polymer composition comprising an anionic polymer composite having a synthesized polymer portion and a polysaccharide portion, obtainable by polymerizing vinyl monomers in the presence of the polysaccharide. The present invention further relates to a strength system and methods of production and use in providing a paper product.
Patent CA-3100576-A1 (CA)
Title: Scaffolds with stabilized mhc molecules for immune-cell manipulation
Inventor: HADRUP SINE REKER
IPC: A61K35/17
Filed: 2019-06-19
Abstract: The present invention relates to artificial antigen presenting cell (aAPC) scaffolds to provide cells with specific functional stimulation to obtain phenotypic and functional properties ideal to mediate tumor regression or viral clearance. In particular, the scaffolds of the present invention comprise stabilized MHC class I molecules comprising a heavy chain comprising an alpha-1 domain and an alpha-2 domain connected by a disulfide bridge, wherein said MHC class I molecules are free of antigenic peptide. The scaffolds can be loaded with antigenic peptide on demand, providing an agile platform for effective expansion and functional stimulation of specific T cells in a peptide- MHC-directed fashion.
Patent CA-3101066-A1 (CA)
Title: Crispr/cas and transposase based amplification compositions, systems and methods
Inventor: ZHANG FENG
IPC: C12Q1/68
Filed: 2019-06-26
Abstract: Provided herein are methods and systems for detecting a target nucleic acid sequence. The method comprises contacting an oligonucleotide comprising the target nucleic acid sequence with a transposon complex; inserting one or more T7 RNA promoters into the oligonucleotide using the transposase; and (c) amplifying the target nucleic acid sequence. The transposon complex may comprise a transposase and a transposon sequence comprising one or more T7 RNA promoters. The target nucleic sequence may be amplified by generating RNA oligonucleotides comprising the target nucleic acid sequence via transcription from the inserted one or more T7 RNA promoters. The amplified target nucleic acid may be detected using a CRISPR Cas13-based detection system.
Patent CA-3101369-A1 (CA)
Inventor: WALLACH TODD
IPC: G01N33/53
Filed: 2019-05-29
Abstract: Epileptic seizures, NES, NS, PNES or NEE are difficult to diagnose and are often difficult to distinguish from several conditions with similar presentations, and therefore, diagnosis of seizures is often a long, expensive, and unreliable process. This invention provides biomarkers for identifying and monitoring seizures and epilepsy, ES, NES, NS, PNES or NEE assays for measuring and assessing biomarker concentration, predictive models based on biomarkers and computational systems for diagnosing, monitoring and predicting therapeutic efficacy associated with seizures and epilepsy, ES, NES, NS, PNES or NEE in all clinical and healthcare settings. Diagnostic and treatment methods, systems, kits, and predictive models provided herein, provide quantitative and/or qualitative assessment in order to allow patients to proceed immediately to diagnostic and/or treatment protocols, and assess therapeutic treatment effectiveness.
Patent CA-3101715-A1 (CA)
Title: Autonomous floor cleaner and docking station
Inventor: BROWN ADAM
IPC: A47L11/40
Filed: 2020-12-03
Abstract: ABSTRACT An autonomous floor cleaning system includes an interlock for physically interlocking an autonomous floor cleaner with a docking station. The interlock selectively engages when the robot is docked at the docking station, and can automatically engage as when a predefined locking criterion is met. The interlock can remain engaged until a predefined unlocking criterion is met.  Methods for docking an autonomous floor cleaner with a docking station are disclosed. Date Recue/Date Received 2020-12-03
Patent CA-3104097-A1 (CA)
Inventor: CARTER JAMES
IPC: E04H4/14
Filed: 2019-06-21
Abstract: A laminar water feature is provided which includes a housing having a deck niche, a niche collar, a spacer ring, and a lid, a laminar vessel having an inlet, an annular pocket, a vertical baffle, a horizontal baffle, a light pipe, a plurality of screens, a cap having an outlet, and threading within an isolated light chamber for removably accepting a lighting source, and a pivot adjustment bracket having a handle with push button assembly, ridge, and detent configuration for fixedly rotatably adjusting the angle of the laminar vessel.
Patent CA-3104391-A1 (CA)
Title: Method for increasing the dosing precision of microfluidic pumps or valves, and welding apparatus and tensioning apparatus for carrying out the method
Inventor: FRISCHE NIKLAS
IPC: F04B19/00
Filed: 2019-11-29
Abstract: The invention relates to a method for increasing the metering precision of microfluidic pumps and valves based on a flexible cover film/membrane and a valve trough, in which the surface of the membrane, which faces the valve trough, is heated using a laser beam.
Patent CA-3108269-A1 (CA)
Title: Method of identifying a source component of particulate debris in an aircraft engine
Inventor: BRILLON LOUIS
IPC: F02C7/00
Filed: 2021-02-04
Abstract: The gas turbine engine can have a set of components, the components of the set all being made of material compositions of the same type having a common at least one main material element, the material compositions having distinct signatures in the form of a varying trace amount of one or more signature element, the distinct signatures varying from one component of the set to another.
Patent CA-3110580-A1 (CA)
Title: Resistance device and method
Inventor: COTIE WANDA JESSIE
IPC: A63B23/20
Filed: 2020-06-25
Abstract: Disclosed herein is a resistive device for insertion into a perineal orifice, such as anus or vagina, the device including: an operative portion for insertion into the perineal orifice, the operative portion including a plurality of bowed, resilient fins having proximal and distal ends, and a tip connected to the plurality of fins at the proximal ends for insertion into the perineal orifice. The resistive device also includes a base connected to the plurality of fins at the distal ends. A method of use is disclosed for inter alia exercising the Kegel muscles using the resistive device.
Patent CA-3113692-A1 (CA)
Title: Monovalent selective cation exchange membrane
Inventor: GU GEORGE
IPC: C25B13/08
Filed: 2019-09-25
Abstract: A monovalent selective ion exchange membrane is disclosed. The membrane includes a polymeric microporous substrate, a cross-linked ion-transferring polymeric layer on a surface of the substrate, and a charged functionalizing layer covalently bound to the ion-transferring layer by an acrylic group. A method of producing a monovalent selective cation exchange membrane is also disclosed. The method may include chemically adsorbing an acrylic intermediate layer comprising a chlorosulfonated methacrylate group to a cross-linked ion-transferring polymeric layer on a surface of a polymeric microporous substrate, aminating the chlorosulfonated methacrylate group to attach an amine group layer, and functionalizing the amine group layer with a charged compound layer to produce the cation exchange membrane. Water treatment systems including the monovalent selective cation exchange membrane and methods of facilitating water treatment including providing the monovalent selective cation exchange membrane are also disclosed.
Patent CA-3113703-A1 (CA)
Inventor: BIGOT AURELIEN
IPC: A01N43/80
Filed: 2019-09-20
Abstract: The present invention relates to compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds; to intermediates for preparing compounds of formula (I), to compositions comprising them and to methods of using them to combat and control insect, acarine, nematode and mollusc pests.
Patent CA-3114495-A1 (CA)
Inventor: BASTIAN CHARLOTTE
IPC: A23C17/00
Filed: 2019-10-03
Abstract: The invention mainly relates to a method for producing a phospholipid concentrate derived from a liquid dairy composition comprising at least caseins and phospholipids, characterized in that it comprises at least the steps of: - passing the dairy composition into an ion-exchange column on a cationic resin, - concentrating the phospholipids of the calcium-depleted dairy composition by means of controlled transmembrane pressure gradient microfiltration, and - recovering the retentate from the microfiltration and obtaining a phospholipid concentrate.
Patent CA-3118059-A1 (CA)
Inventor: CABOT ROSS
IPC: A24B15/167
Filed: 2019-10-31
Abstract: There is provided an aerosolised formulation comprising (i) water in an amount of at least 50 wt.% based on the aerosolised formulation; and (ii) at least one flavour; wherein the aerosolised formulation contains the at least one flavour in an amount of at least 70wt% of the said flavour present in the aerosolisable formulation from which the aerosolised formulation was formed.
Patent CA-3118286-A1 (CA)
Title: Fitting for connecting a main pipe liner to a branch conduit
Inventor: Bontus George
IPC: F16L41/08
Filed: 2019-10-30
Abstract: A fitting for connecting a branch conduit to a liner installed in a main pipe is configured to mechanically connect to the branch conduit as it is inserted into the branch conduit from inside the main pipe. The mechanical connection is established without rotating the fitting. The fitting can include a body having an outer shaft section for being received in the branch conduit and an inner flange section for opposing the liner within the main pipe. The fastener include one or more teeth that extend radially from the exterior of the shaft section. The teeth can be secured to the shaft section by deforming portions of the fitting body against the teeth. The flange section supports a gasket for sealing against the liner when the fitting is installed. The flange section can include a rim that maintains the gasket in the proper position.