baber/WOPTO huggingface dataset:
Patent BG-108069-A (BG)
Title: Animal breeding building with controllable ventilation
Inventor: MIHAJLOV NIKOLAJ
IPC: F24F13/06
Filed: 2003-08-07
Abstract: The invention relates to a building by means of which a facility is made to reduce the energy losses across the roof of the building in the winter, improve the exploitation of the energy of the outgoing air, and the parameters of the air, entering the building for the animal. It comprises external walls (1), having mobile panel (2), roof (3), inlet (4) and outlet (5) airducts fitted in them. Flaps (6) are mounted in the outlet ducts (5). The inlet (4) and outlet (5) airducts are fitted on the roof (3) of the building, being alternated. The inlet airduct (4) comprises a tube (7) conducting the air and former of flat air stream. The beginning of the outlet airducts (5) is close to the floor of the premise.
Patent BG-108494-A (BG)
Title: Pulmonary administration of chemically modified insulin
Inventor: PATTON JOHN S
IPC: A61K47/48
Filed: 2003-12-22
Abstract: The present invention provides active, hydrophilic polymer-modified derivatives of insulin. The insulin derivatives of the invention are, in one aspect, suitable to delivery to the lung and exhibit pharmacokinetic and/or pharmacodynamic properties that are significantly improved over native insulin. 77 claims, 14 figures
Patent BG-110482-A (BG)
Title: Bio mass produced from stain mycelium of higher fungi of high nutrition and biological value
Inventor: TOREV ATANAS
IPC: A01H15/00
Filed: 2009-10-01
Abstract: The present invention relates to a bio mass produced from stain mycelium of higher fungi, containing at least one bio mass produced from stain mycelium of higher fungus selected from the bio masses stain mycelium Lerista nuda LN-06/? NVIMSS 8658, stain mycelium Rolirorus sguamosus RS-64/? NBIMSS 8657 and stain mycelium Inonotus obliguus 05-M/ NVIMSS ? 8433, containing together with the cultural liquid also nutrition substances, particularly proteins, including free amino acids
Patent BG-111420-A (BG)
Title: Composition of an extract of the hippeastrum genus and separate components for the production of medicinal products and food supplements
Inventor: MAHRER CARLOS
IPC: C07D491/06
Filed: 2013-03-07
Abstract: The composition of an extract of the Hippeastrum genus and its separate components is intended for the production of medicinal products and food supplements. The composition contains in weight %: galanthamine from 40 to 98, haemanthamine from 0.01 to 35, narwedine from 0.01 to 10, secondary alkaloids which can be of the homolycorine, and/or tazethyne, and/or montanine and/or galantamine, and/or haemanthamine and/or lycorine type from 0.01 to 35 and non-alkaloid plant metabolites from 0.001 to 1, derived from a total extract of the Hippeastrum genus. The content of alkaloids can range in weight % from 0.01 to 99 and of non-alkaloid plant metabolites and/or different inactive excipients and/or solvents respectively from 1 to 99.9. The composition can be in dry or liquid form. It finds an application for isolating pure compounds such as galanthamine and haemanthamine. 8 claims
Patent BG-112772-A (BG)
Title: Method for adaptive in silico knowledge discovery based on big genomic data analytics
Inventor: IVANOVA DESISLAVA
IPC: G06F17/10
Filed: 2018-07-12
Abstract: A method for adaptive in silico knowledge discovery and decision-making based on big genomic data analytics, which contains two parallel and correlated computational phases, a machine learning phase and an operational phase, which overlap and perform simultaneously, with information exchange. Each phase operates over four types of computational workflows for data analysis - descriptive, diagnostic, predictive and prescriptive analysis. The descriptive, diagnostic, and predictive differentiated workflows are model-based, while the predictive differentiated workflows use models to construct recommendations for personalized therapy and target grouping rules for precision therapy. The input data are four sets - sequenced genomes, clinical test results, parameters of the patient's individual lifestyle and environmental factors. Within the machine learning phase, parallel differentiated workflows are built up, as those with the highest estimate for accuracy, precision and sensitivity are used to construct an integrated knowledge discovery workflow, with the following outputs: mapping of cancer-related genes, detection of mutations, personalized cancer diagnosis and recommendations for a target group for precise patient therapy. The output data is verified by an expert, and if necessary the data sets are modified and the differentiated workflows are performed again in the machine learning phase. The process is repeated iteratively until verification by the oncologist expert. The method is adaptive in terms of genetic, biological and medical aspects, as well as in the computational aspect - scalability, reconfiguration of hardware and software resources.
Patent BG-113473-A (BG)
Title: Utility management system
Inventor: STEFANOV IVAYLO
IPC: G06Q50/00
Filed: 2022-01-21
Abstract: The present invention relates to a utility management system - electricity, heat, water and natural gas, telecommunications, etc. - and will find application in industry and domestic end-users, in particular households, business customers and public institutions. The established utility management system consists of a potential customer connection module (1) linked to an enterprise resource management system (2), which is linked to a data exchange module (3) and a customer module (4). The components of the system are configurable and can be offered as a complete integrated solution, individually or in combination, and can also be integrated with external systems. All system modules are installed and run on workstations or servers. The Utility Management System provides an integrated business solution for managing the entire lifecycle associated with the provision of utilities.
Patent BG-113691-A (BG)
Title: Passive low-pressure apparatus for cooling at adversely elevated temperatures or for suppression of flaming in a protected electrical device
Inventor: Marek Duda
IPC: A62C37/00
Filed: 2023-04-19
Abstract: The passive low-pressure apparatus for reducing adversely elevated temperatures or for suppression of flaming in protected electrical devices according to the present invention is accommodated inside the protected electrical device and consists of carrying body (1) inside which there is some compressed cooling medium (3), wherein said carrying body (1) is also equipped with a charging valve (5) through which the cooling medium (3) is injected into the carrying body (1). Furthermore, there is a pressure gauge (2) for indicative passive control of the cooling medium inside the carrying body (1) and a pressure sensor (4) responsible for disconnecting the protected device from the power supply and connecting it to alarm equipment. Said carrying body (1) is an enclosed hollow compartment of any shape and size made of a plastic, metal or metal alloy, wherein the carrying body (1) is provided with at least one temperature detector, such as a thermal glass vial (6), which breaks inside the protected device when the temperature reaches elevated levels, whereupon the carrying body (1) is ruptured and the medium (3) spills inside the space of the protected electrical device and cools the adversely elevated temperature or suppresses any flaming in said protected electrical device. The thermal glass vial (6) can be attached to the carrying body by several mechanical methods, for example it can be screwed, glued, soldered and so forth. The activation of the apparatus, i.e. the breaking of the glass vial (6) due to the adversely elevated temperature and the resulting creation of a hole in the carrying body (1) through which the medium spills inside the protected electrical device, begins at 50 degrees Celsius.
Patent CN-1263378-A (CN)
Title: 变换器装置
Inventor: HIDEO OKAYAMA
IPC: H02M7/521
Filed: 2000-01-21
Abstract: 一种采用大容量自消弧型半导体器件,可同时实现大容量、低损耗、高可靠性和小型化的变换器装置。本装置由回收电容回收存储于2级或3级变换器电桥的电流变化率抑制器件群中的电能,电能再生电路将再生电能馈给直流电压电路。电能再生电路按与负荷电流的大小成正比地控制回收电容的充电电压。在同一直流电压电路连接有多台变换器电桥时,将其分成多个组,对每组不同的电能再生电路连接到各组的变换器电桥上。
Patent CN-1339917-A (CN)
Title: 视讯解压缩器对同步存储器的高效率存取架构
Inventor: CHEN WENKUAN
IPC: H04N5/91
Filed: 2000-08-25
Abstract: 一种视讯解压缩器对同步存储器的高效率存取架构,主要包括有一同步存储器及一存储器控制器,同步存储器包含有A存储器组及B存储器组,存储器控制器可供自同步存储器读取图像资料进行移动补偿及显示,图像的扫描线在同步存储器的AB存储器组的分布是以四条扫描线为一组周期性地排列,A存储器组是周期性地依序放置第4N+0及4N+1条扫描线,B存储器组则周期性地依序放置第4N+2及4N+3条扫描线,N为正整数。
Patent CN-1335983-A (CN)
Title: 光盘和光盘装置
Inventor: TAKASHI INOUE
IPC: G11B11/105
Filed: 2000-09-07
Abstract: 本发明提供一种适合于高密度记录的取样伺服格式的光盘,能够在不降低可重写信道区域的格式效率的情况下,形成控制信道区域,并且,提供一种光盘装置,能够通过简单的电路构成来在短时间内读出控制信息。为此,在光盘中,对于控制信道区域的各段,接在用与时钟标记、摆动标记和地址标记相同的压印预置凹坑来记录控制数据的数据区域之后,设置不存在压印预置凹坑的预定长度的空白。
Patent CN-1454288-A (CN)
Title: 排气管的防烫隔音设备
Inventor: LIU JEFFERSON
IPC: F01N1/00
Filed: 2000-08-18
Abstract: 本发明公开了一种排气管的防烫隔音设备，它包括一个内层金属板和一个外层金属板，其内、外层金属板相互接合而成为金属密封体，密封体内部是空的，将其中的空气抽尽使其成为高真空状态，利用高真空状态无热传导及声波传导的特点，使排气管所散发的高温与噪音不易传导至外层金属板，以达到防止人体直接烫伤及减少噪音的目的。
Patent CN-1340898-A (CN)
Title: 永磁转子
Inventor: SHINYA NAITO
IPC: H02K1/22
Filed: 2001-08-31
Abstract: 本发明的目的在于减少扭矩波动和减速下变动的扭矩。设嵌入于各对应层的狭缝部12A－12C中的永磁铁PM的长度,按从转子铁心11的外周侧观察的顺序,是L 1 、L 2 =(L 21 +L 22 )与L 3 =(L 31 +L 32 ),则满足关系式SL 2 <SL 3 <与L 1 <L 2 <L 3 。这样,当转子组装到旋转式电力装置中时,在由嵌入到狭缝部12A－12C的各个永磁铁PM分别产生的总磁通量φ 1 、φ 2 、φ 3 间成立下述关系:φ 1 <φ 2 <φ 3 。
Patent CN-1384452-A (CN)
Title: 用于对基于文本的产品进行评估的方法和系统
Inventor: MASAYUKI SAYA
IPC: G06Q30/02
Filed: 2002-04-29
Abstract: 一种系统和基于计算机的方法,用于在计算机环境中,根据例如关于客户已经阅读的文本内容的信息这样的标准信息,提供订制的内容评价和/或评论(或建议)。该系统包括第一(或图书)数据库、客户数据库、用于从数据库中搜索、检索和比较数据的数据库服务器、把数据库服务器连接到网络的网络服务器、以及通过网络连接到网络服务器的客户机。在一个实施例中,客户根据图书评价功能执行图书登记功能。在登记功能中,获得关于已经由客户所阅读的图书和其它期刊的信息,由数据库服务器所编辑并且存储在客户数据库中。
Patent CN-1414782-A (CN)
Title: 液晶显示器支架
Inventor: JUN-SOO CHONG
IPC: F16M11/12
Filed: 2002-08-26
Abstract: 一种液晶显示器支架，其包括基座部分；支架部分，其直立安装在基座部分上并具有将电缆容纳在其中的电缆容纳部分；铰轴，其与支架部分的直立方向交叉设置；第一旋转构件，其在铰轴上上下旋转；第二旋转构件，其可旋转地连接至第一旋转构件，并能沿平面方向旋转液晶显示器。利用这种结构，有可能在内部电缆型液晶显示器上使用倾斜和枢轴结构。
Patent CN-1507307-A (CN)
Inventor: ZHANG WEN
IPC: H05B37/02
Filed: 2002-12-11
Abstract: 一种光线强度自适应台灯，由光强探测器和台灯构成，其特征在于所述的台灯中设置有光强探测器，所述的光强探测器能实时地探测到外部环境的光强，并根据外部环境的光强调节可变电阻器，所述的可变电阻器的变化可以调节台灯的电流大小，进而实现了对台灯光强的调节。
Patent CN-1524302-A (CN)
Inventor: WILSON CHEIKY MICHAEL HAGO
IPC: H01M50/489
Filed: 2002-04-19
Abstract: 本发明涉及一种非均相纤维素电池隔膜(10)，该非均相纤维素电池隔膜由纤维素(12)和具有氢渗透性的聚合物的混合物制成，其用于锌基电池可表现出增强的通过膜的氢传输，同时保持低的电阻，并且表现出抗锌离子传输性，其可阻止锌树枝状晶体的形成。
Patent CN-1604875-A (CN)
Inventor: FENN PHILIP M
IPC: C03B17/06
Filed: 2002-12-10
Abstract: 提供用于通过溢流下拉熔制法制造平板玻璃的熔融玻璃供料系统。该供料系统包括包围第二管道(19)一部分的第一管道(9)，从而在两个管道之间形成熔融玻璃(31)的自由表面(21)。第一管道(9)和第二管道(19)的相互位置使得第二管道(19)的出口端(20)和自由表面(21)之间的空间关系不会在析晶敏感玻璃(如高硅液晶显示器玻璃)的片材制品中产生大量析晶缺陷(27，29)和大量气泡缺陷(35)。
Patent CN-1610774-A (CN)
Inventor: KELTOUM DREESEN
IPC: D05B7/00
Filed: 2002-12-20
Abstract: 本发明涉及用于将一块织物缝合到另一块织物上的机器，该机器包括装有特别包括缝纫机针(5)的针刺装置、一块织物和另一块织物的支持系统(8)、在支持系统(8)和机针(5)之间的相对移动机构(9)、一个用来给包括待针刺线圈的定位纱的一块织物的区域和机针(5)照相的照相机的机体(3)和影像处理和向移动机构和针刺装置发出指令的装置。此机器包括：保证一块织物和另一块织物的支持系统(8)相对于固定的机针(5)移动的机构(9)；和包括将一块织物和另一块织物的整体保持在相对固定的位置上的机构在内的支持系统。
Patent CN-1469595-A (CN)
Inventor: HIDEMOTO ASAKAWA
IPC: H04B10/03
Filed: 2003-05-30
Abstract: 本发明减少了所使用光纤的数量，而不损害环形网络系统的自我恢复功能。构成环形网络系统的多个节点的当前接口通过光纤被连接到一起，与此同时节点的备用接口通过光纤被连接到一起。然而，光纤被连接到并不涉及当前接口信号通信的那些每个当前接口的输入端和输出端，通过这种方法，光纤从输入端连成环路到输出端。
Patent CN-1649824-A (CN)
Inventor: HIROAKI HIBINO
IPC: C07D311/24
Filed: 2003-02-27
Abstract: 一种用于制备由式(4)表示的二羧酸化合物的方法：(4)(其中R 1 和R 2 相同或不同，并且各自为低级烷基；而波浪线表示该化合物是(E)异构体或(Z)异构体或它们的混合物)，其特征在于使由式(2)表示的化合物：(2)(其中R 1 、R 2 和波浪线的含义同上；而X 2 和X 3 中的一个为氢，而另一个为卤代基)，与由式(3)表示的硝基苯酚在碱存在下反应；一种用于制备由式(5)表示的硝基苯并吡喃酮化合物的方法：(5)(其中R 1 的含义同上)，其特征在于使所述二羧酸化合物或其羧酸与酸反应；一种用于制备氨基苯并吡喃酮化合物的方法，所述方法包括使所述硝基苯并吡喃酮化合物还原；和一种用于制备酰氨基苯并吡喃酮化合物的方法，所述方法包括使所述氨基苯并吡喃酮化合物酰化。
Patent CN-1652999-A (CN)
Inventor: JEREMY BARKER
IPC: H01M4/58
Filed: 2003-05-06
Abstract: 本发明的活性材料包括至少一种碱金属和至少一种能被氧化至较高氧化态的其它金属。优选的其它金属相应地选自过渡金属(周期表中第4－11族所定义的)，以及某些其它非过渡金属，例如锡、铋和铅。该活性材料可以通过单步反应或多步反应合成。在合成反应的至少一个步骤中，采用还原性碳作为起始原料。一方面，还原性碳由单质碳供给，优选为如石墨、无定形碳、碳黑等等的微粒形式。另一方面，还原性碳也可由有机前体材料，或单质碳和有机前体材料的混合物供给。
Patent CN-1653790-A (CN)
Inventor: HAMILTON THOMAS E
IPC: H04Q3/545
Filed: 2003-03-18
Abstract: 本发明提供了一种网络中的方法，该方法包括用应用程序接口(API，28)从应用程序接收消息，并将该消息从该API传递给移动业务交换平台(MSSP，22)内的控制进程(26)。还提供了一种系统，该系统包括连接至移动业务交换平台(MSSP)内的控制进程的网关通用分组无线业务支持节点(GGSN，20)，一组连接至该控制进程的全局联网的计算机，连接至该控制进程的应用程序接(API)，以及执行连接至该API的应用进程的应用系统(30)。
Patent CN-1665530-A (CN)
Inventor: STEPHANE DELBECQ
IPC: C12N15/09
Filed: 2003-07-09
Abstract: 本发明提供了免疫原性组合物，其包括融合蛋白和皂苷佐剂。所述融合蛋白包括融合于核心多肽N－端和/或C－端的异源疏水肽。所述核心多肽包括至少一个保护性表位。该组合物中皂苷佐剂以游离形式存在。同样提供的还有疫苗，其包括该免疫原性组合物以及任选的附加免疫活性成分。还提供了制备此类疫苗的方法、以及所述免疫原性组合物用于制造疫苗的用途。
Patent CN-1695224-A (CN)
Inventor: TODA NISHIMURA KIYOSHI WATANAB
IPC: H01J61/32
Filed: 2003-09-01
Abstract: 一种荧光灯(1)包括：通过以下步骤形成的灯泡(2)：加热外管径为12－20mm和管长为800－2500mm的一个直管形灯泡(2a)的弯曲部分－形成预定部分，以便通过弯曲加工提供多个弯曲部分(2c)和与弯曲部分(2c)相邻的直管部分(2b)，从而直管部分(2b)穿过弯曲部分(2c)基本设置在相同平面内；靠近一对端部(2d和2d)形成被密封在其中的电极(5和5)，以便形成穿过直管部分(2b)和弯曲部分(2c)的一个放电路径；在灯泡的内表面上形成荧光层(4)；和密封包括汞的放电媒质；和设置在灯泡(2)的端部(2d和2d)的灯头(6)；由此减少了形成在直管部(2b)的荧光层(4)的热退化，从而抑制了初始光通量的退化，可以以高效率进行发光。根据上述结构，可以提供一种荧光灯，它是紧凑型的并且能以高效率发光，并具有改进的光输出特性，并提供使用这种荧光灯的照明器具。
Patent CN-1723643-A (CN)
Inventor: JAY CAIN JOSEPH BIBB BILLHARTZ
IPC: H04W72/10
Filed: 2003-09-30
Abstract: 一种无线通信网络，包括多个移动节点(12)，每个移动节点包括收发信机(14)、连接到收发信机(14)的诸如相控阵列天线的定向天线(16)、和连接到收发信机(14)的控制器(18)。该控制器(18)为每个时帧调度各自的半永久时隙(18a)以建立与每个相邻移动节点的通信链路并在每个时帧中留下至少一个可用时隙。该控制器(18)还基于链路通信需求调度至少一个可用时隙也服务于与相邻移动节点的通信链路。该定向天线(16)在与每个相邻移动节点通信的过程中由控制器(18)指向每个相邻移动节点。该控制器(18)还基于链路通信需求通过分配时隙协调与每个相邻移动节点的通信。
Patent CN-1060178-A (CN)
Inventor: YANG LUO
IPC: H01F1/053
Filed: 1990-09-22
Abstract: 本发明涉及铁基合金和永磁材料领域，特别涉及

稀土永磁材料。本发明提供一种制备磁各向异性的

稀土-铁-硼合金薄带材料的制备方法及其专用设

备。本发明方法是将稀土-铁-硼合金在熔炼室内冶

炼，而在喷淬室内喷淬于水冷单辊上，熔炼室与喷淬

室彼此分开并仅由喷嘴相连，合金喷淬时，熔炼室与

喷淬室的压差为50～150毫米汞柱，单辊辊速为

16.5～21.5米/秒。使用本发明方法与设备能得到

成本低廉，磁能积高的各向异性微晶永磁材料，方法

与设备简易可行。
Patent CN-1052685-A (CN)
Inventor: HONGBIN WU
IPC: C09G1/14
Filed: 1991-01-11
Abstract: 皮革旅游鞋去污光亮剂及其制法属于皮革制品
洁净方法，本发明是一种以去污为主的洁净法，其特
征在于，它主要由多种表面活性剂、上光剂、胶体和保
湿剂以及去离子水组成，其他还有增白剂、抑菌防腐
剂和增溶剂等。它是一种胶体型油包水式的脂肪类
洁净剂，具有可以去除附着在皮革表面尘土中的钙、
镁等金属离子、油污染和水污染、抗静电以及制备工
艺简单、使用方便等优点。
Patent CN-1075668-A (CN)
Title: 烧结制品制备方法及其中所用的组合物
Inventor: HIGGINS WILLIAM A
IPC: C04B35/632
Filed: 1992-11-20
Abstract: 本发明涉及一种制备烧结型材的方法，该方法包
括下列步骤： 
     (1)由一种混合物成型成生坯体，所述混合物包
括主要量的至少一种无机料粉和一种或多种添加剂；
和(2)坯体的烧结。由本发明组合物制备的烧结制品
有比较高的烧结密度和粒径和比较低的孔体积。
Patent CN-1069017-A (CN)
Title: 卤代烃的氟化方法
Inventor: SHIBANUMA TAKASHI
IPC: C07C17/21
Filed: 1992-05-23
Abstract: 通过卤代烃与氟化氢在氟化催化剂存在下进行反应，可使卤代烃有效的进行氟化，催化剂是含有选自钌和铂的至少一种金属的部分氟化了的三氧化二铬。
Patent CN-1112908-A (CN)
Title: 硅砖的制造方法
Inventor: ICHIKAWA KENJI
IPC: C04B35/66
Filed: 1995-03-01
Abstract: 公开了一个烧制含二氧化硅为主要成分的硅石
料制造硅砖的方法，烧制前在硅石料中加入0.05～0.25wt％的熔化后又固化了的Na 2 O-CaO-SiO 2 和0.1～1.0wt％的铁氧化物(以Fe 2 O 3 计)。这有效地加速了二氧化硅向鳞石英的转变，提供了主要含鳞石英带有少量残留的二氧化硅和无定型玻璃的硅砖，并增进了硅砖的抗蠕变强度。
Patent CN-1156995-A (CN)
Title: 玻璃体结合蛋白受体拮抗剂
Inventor: ALI F
IPC: C07D405/14
Filed: 1995-06-29
Abstract: 本发明公开了玻璃体结合蛋白受体拮抗剂化合物，它们可用于治疗骨质疏松。这些化合物包含与杂环部分相连的纤维蛋白原受体拮抗剂模板。
Patent CN-1173953-A (CN)
Title: 通信业务控制交换设备
Inventor: YASUHIRO NISHIKAWA
IPC: H04L12/56
Filed: 1996-09-05
Abstract: 一种能控制所提供的通信业务的状态的交换机(1)包括分别为用户终端之间的通路配置的相互链接的呼叫控制存储器(131—1至131－M),其中存有用户终端提供的通信业务的所需形式的登记信息。交换机(1)还包括提供通信业务的所需形式的通信业务提供装置(121)和改变存储器(131—1至131－m)链接状况以改变通信业务形式的链接改变控制装置(122)。因此这样的一个单个交换机(1)就能提供各种通信业务形式。
Patent CR-20120211-A (CR)
Title: Métodos de síntesis y purificación de compuestos de heteroarilo
Inventor: HARRIS ROY L
IPC: A61K31/497
Filed: 2012-04-26
Abstract: En la presente se proveen métodos para preparar compuestos de heteroarilo teniendo la siguiente estructura: fórmula (I) o fórmula (II): en donde R1-R4 son como se define en la presente. Los compuestos de heteroarilo son útiles para tratar o prevenir cáncer, condiciones inflamatorias, condiciones inmunológicas, enfermedades neurodegenerativas, diabetes, obesidad, trastornos neurológicos, enfermedades relacionadas con la edad o condiciones cardiovasculares.
Patent CR-20140331-A (CR)
Title: Composiciones herbicidas que contienen bentazón y el inhibidor als y el inhbitor accasa
Inventor: MANN RICHARD K
IPC: A01N43/88
Filed: 2014-07-09
Abstract: Las composiciones herbicidas que contienen (a) bentazon-sódico y (b) un inhibidor de ALS y (c) un inhibidor de la ACCasa que controla las malezas susceptibles y resistentes en los cultivos, por ejemplo, arroz, trigo, cebada, avena, centeno, sorgo, choclo
Patent CR-20160309-A (CR)
Title: Inhibidores de serina/treonina cinasa
Inventor: DO STEVEN;
IPC: C07D498/16
Filed: 2014-12-03
Abstract: La presente invención se refiere a compuestos que tienen la fórmula I en dondeR1, X1, X2, X3 y X4como se define en la presente son inhibidores de la cinasa ERK. También se describen composiciones y métodos para tratar trastornos hiperproliferativos.
Patent EC-SP034648-A (EC)
Title: Construccion de cubierta-cielo raso con techo plano, compuesto,doblemente pretensado para edificaciones industriales con vano de gran distancia
Inventor: SKENDZIC MILOVAN
IPC: E04C3/17
Filed: 2003-06-11
Abstract: Las construcciones de cubierta - cielo raso con techo plano, compuesto, doblemente pretensado, para construir edificaciones con un gran vano, conlleva un espacio plano y elementos de ensamblaje prefabricados. Resuelven el problema de construir un techo plano con cielo - raso terminado en edificaciones con un gran vano en donde, además de un aspecto muy estético del cielo raso se reduce el volumen de calentamiento, se garantiza el espacio de la galería adecuadamente ventilado y aislado, gracias al cual las instalaciones pueden hacerse sin que se vean. La construcción en acero (2), interconectadas por medio de elementos verticales. La construcción se pre-tensiona dos veces mediante dos métodos independientes. La placa de concreto del techo se pretensiona céntricamente en el molde (6) y después de que la placa de concreto (1) he endurecido, la construcción superior en acero (2) se pre-tensa separando en el centro las dos mitades de acero (2) que enseguida se conectan. El pretensado de la placa del techo (1) se aplica para para eliminar o reducir las fisuras en el concreto mientras se pre-tensa la construcción superior mientras que la separación de las dos mitades de acero (2) se utiliza para controlar las deflexiones.
Patent EC-SP044966-A (EC)
Title: Compuesto polimorfo estable de flibanserina, procedimeinto industrial para su preparacion, y uso del mismo para preparar medicamentos
Inventor: BOMBARDA CARLO
IPC: A61P/
Filed: 2004-01-30
Abstract: Esta invención se relaciona con el polimorfo A de flibanserina (1), para un proceso técnico para la preparación del mismo, así como también para el uso del mismo para la preparación de medicamentos.
Patent EC-SP088486-A (EC)
Inventor: FEUERBACH DOMINIK
IPC: C07D471/08
Filed: 2008-05-30
Abstract: The present invention relates to compounds of formula (I)   
wherein 
n represents 0, 1, 2, 3, 4 or 5, 
R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate 
Y represents one of the following groups:   
in free base or acid addition salt form, to processes for their production to pharmaceutical compositions comprising them and for use as cholinergic ligands of n-AChR.
Patent EC-SP088744-A (EC)
Inventor: RACZ N SANDOR
IPC: A61B18/18
Filed: 2008-09-18
Abstract: An ablation instrument including a body and an ablating member is provided. The body includes a distal end and a surface with the ablating member coupled toward the distal end of the body. The ablating member includes a lesion wire extending through and along a portion of the surface of the body for creating lesions in a target tissue while the body serves to isolate surrounding tissue from the target tissue. A method of ablating a target area is also provided.
Patent EC-SP109962-A (EC)
Title: Nuevos compuestos antimicrobianos, su síntesis y su uso para el tratamiento de infecciones en mamíferos
Inventor: MAKAROV VADIM A
IPC: A61K31/5415
Filed: 2010-02-12
Abstract: La presente invención se refiere a nuevos compuestos antimicrobianos, a su síntesis y a su uso para el tratamiento de infecciones en mamíferos. La presente invención está dirigida a la generación de nuevos compuestos con actividad contra mycobacterias como nuevos fármacos potenciales contra la tuberculosis para superar problemas concernientes a la resistencia y a la intolerancia a fármacos. Este objetivo ha sido resuelto proporcionando compuestos de la fórmula 1, en donde R1 y R2 son, independientemente uno del otro, NO2, NR7R8, NHOR9, COOR9, CN, CONR10R11, CHO, F, Cl, Br, SO2NR12R13, alcoxi inferior, OCF3, mono-, di o trifluorometilo; R3 y R4 son, independientemente uno del otro, H, un radical alifático saturado o insaturado, lineal o ramificado con 1-3 miembros en la cadena, F, Cl, Br, alcoxi inferior; R5 es H, un radical alifático saturado o insaturado, halogenado o no halogenado, lineal o ramificado, con 1 -7 miembros en la cadena; R6 es un radical; donde X es un radical alifático saturado o insaturado, halogenado o no halogenado, lineal o ramificado, con 1-5 miembros en la cadena, o R5 y R6 juntos representan radicales bivalentes donde n es 1-4; R7 - R13 son, independientemente unos de los otros, H o un radical alifático saturado o insaturado, halogenado o no halogenado, lineal o ramificado, con 1-5 miembros en la cadena, fenilo, bencilo o R7 y R8 juntos, R10 y R11 juntos, R12 y R13 juntos, representan un radical alifático bivalente, lineal o ramificado, con 1-7 miembros en la cadena; R14 y R15 son, independientemente uno del otro, H, un radical alifático lineal o ramificado con 1-5 miembros en la cadena, F, Cl, Br, NO2, NH2, CF3.
Patent EC-SP972192-A (EC)
Title: Derivados de sulfonamida de la formula n-(4-aril- thiazol-2-yl)-y su uso
Inventor: CESURA ANDREA
IPC: C07D277/52
Filed: 1997-07-17
Abstract: El invento se refiere al empleo de derivados de sulfonamida de la fórmula general (gráfico), en donde R significa alquilo inferior, fenilo, bencilo, naftilo, piridilo o tienilo, opcionalmente sustituido por uno o más sustituyentes de alquilo inferior, alcoxilo inferior, alquilo inferior-carbonil-amino, halógeno, cicloalquilo, nitro, amino, metilendioxilo, fenoxilo benciloxilo y los anillos aromáticos pueden estar sustituidos a su vez, por nitro, halógeno o amino. R1-R4 significan hidrógeno, halógeno, hidroxilo, alquilo inferior, nitro, ciano, amino, alcoxilo inferior, benciloxilo, trifluorometilo o fenilo, opcionalmente sustituído por uno o más sustituyentes de alquilo inferior, trifluorometilo, nitro, amino o hidroxilo y en donde R1 y R2 o R2 y R3 juntos pueden formar un anillo de benceno que opcionalmente pueden estar sustituido por halógeno, trifluorometilo, nitro, alquilo inferior o alcoxilo inferior, y de sus sales farmacéuticamente aceptables como inhibidores de quinurenin-3-hidroxilasa en el control o prevención de tratornos neurodegenerativos, trastornos neurológicos resultantes de una activación del sistema inmune, o enfermedades psiquiátricas y respectivamente para la producción de medicamentos correspondientes.
Patent EC-SP972207-A (EC)
Title: Metodo para la sintesis de analogos de la hormona paratiroidea y del peptido relacionado con la hormona paratiroidea (caso ran 4105/190)
Inventor: ARZENO HUMBERTO
IPC: C07K14/47
Filed: 1997-07-29
Abstract: Se proporciona un proceso de condensación de fragmentos para la sintesis de análogos de la hormona paratiroidea(pth) y del péptido relacionado con la hormona paratiroidea (PTHrP), en el que los residuos amino ácidos (22-31) forman una élice alfa anfipática sintética.