baber/WOPTO huggingface dataset:
Patent NZ-718792-A (NZ)
Title: Combination therapy of an anti cd20 antibody with a btk inhibitor
Inventor: KLEIN CHRISTIAN
IPC: C07K16/28
Filed: 2014-11-04
Abstract: The present invention is directed to the combination therapy of an anti-CD20 antibody with a BTK inhibitor for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with a type I anti-CD20 antibody or an afucosylated humanized B-Lyl antibody and a BTK inhibitor.
Patent NZ-720708-A (NZ)
Title: Pre-moistened wipes for use in treating anal-rectal irritations and disorders
Inventor: AGISIM GARY ROBERT
IPC: A61K8/86
Filed: 2014-12-08
Abstract: Many people who suffer from anal rectal discomfort and disorders need fibrous sheet materials which are pre-moistened with a solution for improved cleansing without excessive skin irritation. The invention particularly concerns wet wipes, such as anal- rectal wipes, which comprises a solution comprising hamamelis water or witch hazel, to effectively treat anal-rectal disorders.
Patent NZ-725118-A (NZ)
Title: Container
Inventor: ICHIKAWA TORU
IPC: B65D1/28
Filed: 2015-02-26
Abstract: [Problem] To provide an easily disposable container, which stands on its own and can be held easily regardless of the amount of remaining contents even though the container body is configured from a laminate film and for which the volume of the container can be easily reduced after use. [Solution] The container (1) according to an embodiment is provided with: a body member (2) with an open upper end (2a), the body member being formed from a laminate film (10) so as to be capable of standing on its own; and a frame member (3), which is provided so as to bond to the outer circumferential surface of the open upper end (2a) of the body member (2) and which reinforces the rim of the open upper end (2a) so that the open upper end (2a) maintains a specified open shape. The frame member (3) has container-holding areas (4), which are provided where fingers contact the body member (2) when holding the body member (2) and which extend downward from the frame member (3) partway down the body member (2).
Patent NZ-726475-A (NZ)
Title: Antiviral compounds
Inventor: BACON ELIZABETH
IPC: C07D513/04
Filed: 2011-11-16
Abstract: Provided is a selection of hepatitis C virus (HCV) inhibitors with a imidazole-biphenyl-imidazole core. Further disclosed are compounds of the general formula (I), where W1a is selected from 101-116, 125 and 130, and the other variables are as defined in the specification.
Patent NZ-735093-A (NZ)
Title: Inhibitors of hepatitis c virus polymerase
Inventor: JACOBSON IRINA C
IPC: C07D307/84
Filed: 2016-03-23
Abstract: The present invention provides, among other things, compounds represented by the general Formula I: (I) and pharmaceutically acceptable salts thereof, wherein L and A (and further substituents) are as defined in classes and subclasses herein and compositions (e.g., pharmaceutical compositions) comprising such compounds, which compounds are useful as inhibitors of hepatitis C virus polymerase, and thus are useful, for example, as medicaments for the treatment of HCV infection.
Patent NZ-735250-A (NZ)
Title: Pyrrolidine carboxamido derivatives and methods for preparing and using the same
Inventor: CHOI GILDON
IPC: C07D207/10
Filed: 2016-07-08
Abstract: Pyrrolidine carboxamido derivatives, optical isomers thereof, and salts thereof that are able to prevent, improve, and/or treat inflammatory conditions, including inflammatory bowel disease, and methods for preparing and using the same are provided.
Patent NZ-740700-A (NZ)
Title: Methods and compositions for determining resistance to androgen receptor therapy
Inventor: SMITH NICHOLAS
IPC: C12Q1/68
Filed: 2013-07-26
Abstract: Described herein are modified androgen receptor polypeptides that are resistant to inhibition by an androgen receptor inhibitor. Described herein are compositions, combinations, and kits containing the modified androgen receptor polypeptides and methods of using the modified androgen receptor polypeptides. Also described herein are methods of using the modified androgen receptor polypeptides as screening agents for the identification and design of third-generation androgen receptor modulators. Also described herein are third-generation androgen receptor modulators that inhibit the activity of the modified androgen receptor polypeptides. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such androgen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions, including cancers, such as castration resistant prostate cancers, that are mediated or dependent upon androgen receptors.
Patent NZ-743945-A (NZ)
Title: Sliding gate valve plate
Inventor: COLLURA MARIANO
IPC: B22D41/22
Filed: 2017-01-24
Abstract: The present invention concerns a sliding gate valve plate for a molten metal gate valve having: - an upper surface, - a lower surface, said upper and lower surfaces being planar and parallel to one another, - a connecting outer surface connecting the upper surface to the lower surface and - a pouring channel fluidly connecting the upper surface (2) to the lower surface (3), said pouring channel having a pouring axis of symmetry (Xp), wherein the upper and lower surfaces have geometries defined by the following ratios: R1 = LOl1/LOu1, comprised between 50 and 95%, preferably between 57 and 92%, more preferably between 62.5 and 90%, R2 = LOl2/LOu2, comprised between 50 and 95%, preferably between 57 and 92%, more preferably between 62.5 and 90%, R3 = LAl1/LAu1, greater than or equal to 75%, preferably greater of equal to 90%, more preferably greater of equal to 95%, R4 = LAl2/LAu2, greater than or equal to 75%, preferably greater of equal to 90%, more preferably greater of equal to 95% LOu1 and LOu2 are two segments meeting at the pouring axis of symmetry, Xp, and which together form the upper longitudinal extent, LOu, defined as is the longest segment connecting two points of a perimeter of the upper surface and intersecting the pouring axis of symmetry (Xp); LAu1 and LAu2 are two segments meeting at the pouring axis of symmetry, Xp, and which together form the upper latitudinal extent, LAu, defined as the extent normal to and intersecting both the pouring axis of symmetry, Xp, and the upper longitudinal extent, and similarly, LOl1 and LOl2 are two segments meeting at the pouring axis of symmetry, Xp, and which together form the lower longitudinal extent, LOl, defined as is the longest segment connecting two points of a perimeter of the lower surface and intersecting the pouring axis of symmetry (Xp); LAl1 and LAl2 are two segments meeting at the pouring axis of symmetry, Xp, and which together form the upper latitudinal extent, LAl, defined as the extent normal to and intersecting both the pouring axis of symmetry, Xp, and the lower longitudinal extent. The segments have a geometry in that sliding gate valve plate further has a ratio of longitudinal segments (LOu1 and LOI1) connecting at the level of the pouring axis of symmetry (Xp), LOI1/LOu1 = R1 between 50 and 95% this reduces problems linked to air ingress (air penetration) and finning episodes (molten metal penetration)
Patent NZ-746439-A (NZ)
Title: Antibody-drug conjugate
Inventor: MASUDA TAKESHI
IPC: C07K16/28
Filed: 2013-10-10
Abstract: Provided is a method for producing an antibody-drug conjugate, in which a drug-linker structure represented by the following formula is conjugated to an antibody via a thioether bond, -(Succinimid-3-yl-N)-CH2CH2CH2CH2CH2-C(=O)-GGFG-NH-CH2-O-CH2-C(=O)-(NH-DX) comprising a step of treating the antibody in a reducing condition and thereafter reacting the antibody with a compound represented by the following formula: (maleimid-N-yl)-CH2CH2CH2CH2CH2-C(=O)-GGFG-NH-CH2-O-CH2-C(=O)-(NH-DX) wherein, (maleimid-N-yl)- is a group represented by the formula (a), wherein the nitrogen atom is a connecting position, (Succinimid-3-yl-N)- has a structure represented by the formula (b), which is connected to the antibody at position 3 thereof and is connected to a methylene group in the linker structure containing this structure on the nitrogen atom at position 1, -(NH-DX) represents a group represented by the formula (c) wherein the nitrogen atom of the amino group at position 1 is a connecting position, and -GGFG- represents a tetrapeptide residue of -Gly-Gly-Phe-Gly-.
Patent NZ-770095-A (NZ)
Title: Textile patient interface
Inventor: FORMICA JUSTIN JOHN
IPC: A61M16/06
Filed: 2015-11-26
Abstract: A patient interface for sealed delivery of a flow of air at a continuously positive pressure with respect to ambient air pressure to an entrance to a patient’s airways, comprising a plenum chamber (3200) connected to a seal forming structure (3100) comprising an air impermeable membrane comprising a first textile material (3109) having one or two nasal holes (3101) to direct the flow of air to the patient’s nares. The seal forming structure further comprises a foam undercushion (3114) that comprises a pair of alar sealing regions (3113) configured to compress into the corners of the patient’s nose, wherein the foam undercushion is shaped such that a first portion of the membrane is supported by the foam undercushion and a second portion of the membrane is not supported by the foam undercushion. An outer periphery (3115) of the membrane is joined to the foam undercushion with an airtight bond and the membrane is configured to cover the foam undercushion such that, in use, the membrane can inflate away from the foam undercushion and seal at the corners of the patient’s nose. The invention provides a seal forming structure that is comfortable for the user with less leakage of supplied air.
Patent PT-102151-A (PT)
Title: Methods of co-polymerisation of natural oils
IPC: C08K13/02
Filed: 1998-05-05
Abstract: The present invention deals with methods for the co- polymerisation of a mixture among oils with double bonds, by means of addition of sulphur or of cashew shell oil, at a temperature of around 150 degrees Celsius. The present invention also deals with the products obtained by said methods. These products are polymers which can be used, in the form of polyols, in the polyurethane industry.
Patent PT-103661-A (PT)
Title: Processo de preparação de minociclina base cristalina
Inventor: HEGGIE WILLIAM
IPC: C07C237/26
Filed: 2007-02-23
Abstract: O PRESENTE INVENTO DIZ RESPEITO A MINOCICLINA BASE CRISTALINA INCLUINDO TRÊS NOVAS FORMAS POLIMÓRFICAS, E REFERE-SE TAMBÉM A UM PROCESSO PARA OBTER MINOCICLINA BASE PURA SOB FORMA CRISTALINA EM QUE TODAS AS IMPUREZAS ESTÃO CONTROLADAS A VALORES BAIXOS, EM ESPECIAL A IMPUREZA 4-EPI MINOCICLINA.
Patent PT-106810-A (PT)
Title: Sistema de proteção de corrente cravada no crenque para bicicletas
Inventor: MIRANDA JO O CARLOS RIBEIRO
IPC: B62J13/06
Filed: 2013-02-27
Abstract: O PRESENTE INVENTO REFERE-SE A UM SISTEMA DE PROTEÇÃO DE CORRENTE QUE EM VEZ DE SER APARAFUSADO À RODA DENTADA (5) É CRAVADO NO CRENQUE (2) PARA O QUE SE CONSTRUIU UMA PROTECÇÃO DE CORRENTE INOVADA (9)COM UM DIÂMETRO INTERNO IDÊNTICO AO DIÂMETRO EXTERIOR DO CRENQUE(2)NA ZONA DE CRAVAMENTO.
Patent RU-94010146-A (RU)
Inventor: TOKAREV V A
IPC: A01B79/02
Filed: 1994-03-22
Abstract: FIELD: agriculture. SUBSTANCE: method involves presowing treatment of field; sowing and pre-emergence treatment operations. Seed sowing is conducted by four-row pattern with row spacing width of 20x40x20 cm and operating track of 140 cm. It allows yield to be increased by 40%. EFFECT: increased efficiency by reduced power consumption, elimination of herbicides from method and provision for usage of row-crop tractors without narrow tires or caterpillars. 2 cl, 1 dwg
Patent RU-94011334-A (RU)
Inventor: BALJAKIN K N
IPC: G01L7/20
Filed: 1994-03-30
Abstract: FIELD: instruments. SUBSTANCE: offered liquid barometer has closed vessel with colored liquid, for instance, water, and tube open on top and dipped into liquid. As water is 13.5 times tighter than mercury, width of scale and accuracy of readings is increased the same number of times. Barometer can be used in meteorology, school laboratories, etc. EFFECT: enlarged operating capabilities.
Patent RU-94011864-A (RU)
Inventor: BABAEV I K
IPC: B44D7/00
Filed: 1994-04-05
Abstract: FIELD: control over harmful bioagents (insects, microorganisms) destructing pieces of distemper paintings (ikons), polychromine wooden sculpture and decorative carvings, objects made of leather, fur, feathers, woolen textile, graphic materials, documents, books, etc; may be used in museums, book depositories, quarantine stations, customs houses, storehouses, shops, pawnshops and so on. SUBSTANCE: gear has chamber to treat displays, door with sealing to load/unload displays, fan for ventilation of chamber, fumigant, gas-dynamic path which includes confusor, second fan, heater, device for injection of fumigant and condenser placed in series. Inlet to gas-dynamic path is connected to upper part of space of chamber through air-tight gate. Outlet from gas-dynamic path is joined to lower part of space of chamber also through air-tight gate. Paradichlorinebenzol or thymol are chosen as fumigant. EFFECT: prevention of harmful effects of toxic components on personnel and environment, increased efficiency of process of treatment of displays, reduced time for their treatment.
Patent RU-94027930-A (RU)
Inventor: FOL KIN V JA
IPC: B23B5/14
Filed: 1994-07-22
Abstract: FIELD: machine-tool industry, method is used for complete working of pieces butts including cutting head off. SUBSTANCE: method of pieces butts working is exercised in special lathe with numerical program control and central drive. Lathe is equipped with two supports and two spindle stocks located on bed-frame between supports. Worked piece 2 is placed on prisms. Following operations are exercised: butt cutting, centering, drilling. Before them head cutting is exercised in two stages. At first using cutting tool 1 groove is cut through in piece 2 with capable to hold head back crosspiece d = 0.2 D with d - crosspiece diameter, D - blank diameter. After that head is finally separated by rotating disk saw 3 cutting crosspiece with piece fixed. Remaining ridge is removed by cutting tool. EFFECT: improved process. 1 cl, 6 dwg
Patent RU-94029680-A (RU)
Inventor: PITER BRJUS
IPC: B63B21/44
Filed: 1992-11-27
Abstract: FIELD: shipbuilding. SUBSTANCE: shipboard drawing anchor 1 has flue 8 and tail-piece 3 secured to flue 8. Shipboard anchor is used for draw embedding in bottom at anchorage by pulling anchor 1 mainly horizontally by tail-piece 3. Two modes of operation of anchor are proposed by means of lines passing between point of attachment (4A, 4B) of anchor chain and tail-piece and centroid of flue 7. Lines are varying. First line is used for draw sinking of anchor 1 and second line is used for drawing the sunken anchor; tension force at anchor may be directed upward due to increased holding power of anchor due to area of flue lying across relative to lifting force. Change of direction from first line to second line may be effected by means of tail-piece 3 swinging on axle; swinging is controlled by means of control devices which ensure selective swinging of tail-piece on axle. Two separate points (4A, 4B) for securing the anchor chain on tail-piece 3 are alternatively presented as first example with two separate chains secured to these points due to which two modes of operation of anchor are obtained by transfer operation from first chain to second one. Second example illustrates motion of single anchor chain by means of guide from first point of attachment (4A) to second point (4B). EFFECT: enhanced reliability.
Patent RU-94031203-A (RU)
Inventor: BRJUNO OBER
IPC: F26B3/347
Filed: 1992-12-22
Abstract: FIELD: product drying and spraying in solution or in suspended form in liquid. SUBSTANCE: method involves, essentially, injection of mentioned solution of suspension in crosswise direction into single-mode waveguide 3 wherein microwave radiation is propagated at standing wave mode. Device for implementing this method is shown in description of the invention. EFFECT: facilitated procedure. 1 dwg
Patent RU-94036710-A (RU)
Inventor: NISHEVA E S
IPC: G01N33/48
Filed: 1994-09-30
Abstract: FIELD: medicine, allergology. SUBSTANCE: before therapeutic effect patient blood is examined in vitro. Lymphocyte suspension is divided for two parts: control sample has solvent and experimental one has ketotifen solution at final concentration 100 ng/ml. Both samples were incubated for 2 h and content of nonadhesive lymphocytes in each sample is counted. Patient is diagnosed as therapeutically sensitive if content of nonadhesive cells in experimental sample is decreased by 30% and above as compared with that in control one. EFFECT: improved method of assay. 4 tbl, 2 ex
Patent RU-94041547-A (RU)
Inventor: LOPAEV V N
IPC: H04N13/00
Filed: 1994-11-17
Abstract: FIELD: television engineering. SUBSTANCE: stereoscopic image transmission is possible only with aid of stereo adapter on television camera. Stereoscopic image is displayed on TV, monitor, video projector screens with aid of mirror stereoscope in first case, polarized filters (polaroids) in second case. Mirror stereoscope will take the form of polarizing spectacles upon updating it. EFFECT: simplified method enabling each family to obtain stereoscopic image on their screen.
Patent RU-94044329-A (RU)
Inventor: KHERMANUS DE VIL ER STEJN
IPC: H01T13/39
Filed: 1994-12-21
Abstract: FIELD: electrical engineering. SUBSTANCE: in proposed glow plug or other electrode-igniter portion of one, both or all electrodes is made of material containing intermetallic compound with melting point exceeding 1400 C and featuring adequate thermal shock resistance, strength and electric conductivity. Intermetallic compound can form one phase of multiphase connection. Ruthenium aluminide is preferable for use as intermetallic compound. EFFECT: enlarged operating capabilities.
Patent RU-95103728-A (RU)
Inventor: DZHEJMS SALVATORE B JANKO
IPC: G06K19/10
Filed: 1995-03-15
Abstract: FIELD: secure identification. SUBSTANCE: method involves putting strip which has diffraction pattern on article to labeled. Said strip has area where sequential elements with diffraction pattern are located . Each element is used for diffraction of light which is received from light source from at least one of three chosen different planes. Diffraction pattern elements are exposed to light and variations in plane of diffracted light are measured in process of sequential illumination of these elements with diffraction pattern. First information representation is generated for changes in these plane. Said information representation is stored and each subsequent sequential illumination of elements with diffraction patterns and detection of changes in plane of diffracted light are used for generation of second information representation which is compared against first one in order to detect authenticity of this article. EFFECT: increased functional capabilities.
Patent RU-95106668-A (RU)
Inventor: ALLEN D URFER
IPC: C11D3/382
Filed: 1993-08-16
Abstract: FIELD: purification of solid surfaces. SUBSTANCE: concentrated compositions for purification of solid surfaces contain turpentine and/or terpenes together with nonionic and/or anionic surfactants. Said compositions are prepared as transparent liquids which retain their transparency after dilution. EFFECT: improves quality of desired product.
Patent RU-95111501-A (RU)
Inventor: CHESNOKOV B P
IPC: F02M25/025
Filed: 1995-07-11
Abstract: FIELD: engine engineering. SUBSTANCE: standard fuel feeding system is provided with an emulsifying member that is interposed between the dispergator and high- pressure fuel pump. EFFECT: enhanced stability of emulsion.
Patent RU-95115377-A (RU)
Inventor: NEDAJVODA A K
IPC: B64G5/00
Filed: 1995-08-31
Abstract: FIELD: rocketry; construction of pneumohydraulic and electric service lines of multi-stage launch vehicle and their connection with ground service lines. SUBSTANCE: oxidizer filling and draining pipes lines 13 and fuel filling and draining pipe lines 18, as well as plug connectors 24 for connection of launch vehicle with ground complex are mounted in separate detachable module located in parallel with axis of case of launch vehicle and connected with case by means of detachable load-bearing unit provided with pushers. Module case is divided by partition into two hermetic chambers: oxidizer chamber 10 and fuel chamber 11. Electric lines 22 and rocket holding engines are mounted on the outside of module case. EFFECT: increased weight of payload due to reduced weight of structural members of storages.
Patent SA-04250168-A (SA)
Inventor: ALSTERMARK EVA-LOTTE LINDSTEDT
IPC: C07C22/00
Filed: 2004-06-16
Abstract: يتعلق الاختراع الحالي بتوفير مركبات لها الصيغة (I) وعملية لتحضير تلك المركبات واستخدامها ق علاج حالات إكلينيكية تحتوى على الاضطرابات الدهنية (اضطراب الدهون فى الدم) سواء كانت مصاحبة بمقاومة الإنسولين أم لا، وطرق لاستخدامها العلاجى وتركيبات صيدلانية تحتوى عليها.
Patent TW-200300172-A (TW)
Title: Phytase-containing animal food and method
Inventor: WEBEL DOUGLAS M
IPC: A23L33/00
Filed: 2002-10-31
Abstract: A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
Patent TW-200417119-A (TW)
Title: Error amplifier, DC voltage conversion circuit and method thereof
Inventor: TZENG GUANG-NAN
IPC: H03F1/30
Filed: 2003-02-18
Abstract: The present invention discloses an error amplifier, DC-DC converter and method thereof, wherein the soft-start function of the DC-DC converter is set in the error amplifier. By adding the soft-start function, the output voltage of the error amplifier follows the slowly rising soft-start voltage when the DC-DC converter starts. When the soft-start voltage exceeds the steady-state output voltage of the error amplifier, the soft-start loses control of the error amplifier, and the error amplifier is totally controlled by the input end of the error amplifier. Thus, the output voltage jitter of the error amplifier and the DC-DC converter can be eliminated or greatly reduced.
Patent TW-200306722-A (TW)
Title: Address assigner and router
Inventor: MATSUDA YOSHINORI
IPC: H04L12/54
Filed: 2003-03-19
Abstract: A NAT router is disclosed in which the communication can be performed properly even in the application of writing the IP address information into the data section of the IP packet. The NAT router (100) assigns the address which same as the public IP address (B) assigned to the global interface of the router, to one computer (400a) connected to the internal network. The address which same as the public IP address (A) assigned to the upstream IP device (200), and the predetermined private IP address(X), are assigned to the local interface. Accordingly, the communication can be performed properly even in the case of the public IP address of the IP packet is written into the data section, and transmitted from the internal network to the external network.
Patent TW-200406419-A (TW)
Title: 5-Androsten-3 β- ol steroid intermediates and processes for their preparation
Inventor: WHITE MICHAEL J
IPC: C07J1/00
Filed: 2003-03-21
Abstract: The present invention provides 5-androsten-3 β-ol steroid intermediates and processes for their preparation.