baber/WOPTO huggingface dataset:
Patent DK-2858646-T3 (DK)
Inventor: FLYNN DANIEL L
IPC: A61P35/00
Filed: 2012-06-07
Granted: 2018-03-19
Abstract: The invention relates to dihydronaphthyridines and related compounds; compositions comprising an effective amount of a dihydronaphthyridine or a related compound; and methods for treating or preventing proliferative diseases comprising the administration of an effective amount of a dihydronaphthyridine or a related compound. The present invention discloses the unexpected utility of compounds that inhibit cKIT kinase across a broad range of c-KIT mutations, including complex occurrences of primary mutations (KIT exon 9 or 11) and secondary KIT mutations (exons 13, 14, 17 and 18) that may arise in individual, refractory GIST patients. Also unexpected is the utility of compounds of the present invention to inhibit the problematic exon 17 D816V c-KIT mutation, for which there is currently no effective therapy.
Patent DK-2860192-T3 (DK)
Inventor: JÄGER UTE
IPC: G01N33/574
Filed: 2006-10-12
Granted: 2018-01-02
Abstract: The present invention provides novel antibodies and functional fragments thereof specific for CD38, and methods of using the same for the treatment of diseases associated with CD38 expression, including hematological malignancies such as multiple myeloma.
Patent DK-0386647-T3 (DK)
Inventor: NILSSON PEKKA WALDEMAR
IPC: F16K47/02
Filed: 1990-03-02
Granted: 1993-09-27
Abstract: The invention relates to a damping means for pressure to be used in sanitary fittings, which reduces pressure shocks exerted on the pipework by the closing of the the sanitary fitting. The damping means for pressure shocks consists. of a plate-shaped body part (1), in which has been formed; cold and hot water passages (4) passing through the plate having openings (3) in their walls; chambers (10) communicating through the openings (3) with the cold and hot water passages (4) and through the outlet pipes (8) and the slots (6) with the supply pipe of the faucet; pressure damping members (5, 7) in the chambers (10) consisting of a spring (7) which in its rest position covers the openings (3); in case of a pressure shock the spring (7) retracts, the ball (5) withdraws from the mouth of the openings (3) and water can flow through the openings (3) to the chambers (10) and through the outlet pipes (8) and the slots (6) from the chambers (10) into the supply pipe of the faucet.
Patent DK-0430563-T3 (DK)
Inventor: YAMAMOTO KOZO
IPC: F16B23/00
Filed: 1990-11-21
Granted: 1994-03-14
Abstract: A threaded fastener having a groove (13) or projection in a head (2) for engagement of jointing equipment is disclosed. The groove (13) or projection is composed of a center portion (A) and a radial portion (B) extending radially, outward of circumference of the center portion (A). The radial portion (B) includes a straight portion (13a) for receiving torque constantly and a rounded corner (13b) to prevent stress concentration for providing substantial strength against press-molding and applied torque.
Patent DK-0470133-T3 (DK)
Inventor: MOORTELE GUIDO VAN DE
IPC: G01F15/00
Filed: 1990-04-23
Granted: 1994-07-11
Abstract: PCT No. PCT/BE90/00018 Sec. 371 Date Oct. 28, 1991 Sec. 102(e) Date Oct. 28, 1991 PCT Filed Apr. 23, 1990 PCT Pub. No. WO90/13765 PCT Pub. Date Nov. 15, 1990.Safety valve, characterized in that it principally consists of a housing (1), provided with an inlet (2) and and outlet (3); a main cut off valve (4) installed in the housing (1); and means working together with the flow of liquid which with the removal of liquid and after a lapse of time shut the main cut off valve (4), which are reset in their starting position each time an equal or almost equal pressure in the liquid is created at the inlet (2) and outlet (3) of the safety valve and which when the main cut off valve (4) is shut, hold it shut as long as a well defined drop of pressure remains in existence over the main cut off valve (4), whereby these means are driven by means of a by-pass, such by means of a channel (6) that is situated apart from the main passage (5).
Patent DK-0476960-T3 (DK)
Inventor: VESTBERG TORVALD
IPC: C08F255/02
Filed: 1991-09-17
Granted: 1995-12-18
Abstract: A method for preparing a polyolefine - vinyl polymer composite in which   a) 10-200 weight fractions of vinyl monomer and 0.01-4.0 weight fractions, based on 100 weight fractions of vinyl monomer, of a free radical polymerisation initiator are impregnated into 100 weight fractions of polyolefine particles by blending these at a temperature of 20-100 DEG C, while continuously or discontinuously adding 1-60% by weight of water based on the total weight of the vinyl monomer and the polyolefine, during the maintenance of the particle structure of the polyolefine; b) a water suspension is prepared by adding to the above-mentioned mixture after a completed impregnation suspension water, whereby the total quantity of water becomes 80-1000 weight fractions, based on 100 weight fractions of polyolefine and vinyl monomer, as well as a stabilising agent; c) the temperature of the water suspension is increased to polymerise the vinyl monomer.
Patent DK-0453378-T3 (DK)
Inventor: LOPEZ GEORGES ANTOINE
IPC: A61M39/16
Filed: 1991-03-28
Granted: 1994-09-26
Abstract: This protective structure for a connection site for medical use is of the type comprising sites (A) for connection to at least one valve (3) integral with a fixation palette (5), a casing (B) mounted slidably on the palette (5) and consisting of two half shells (8a-8b) made of synthetic material, articulated via their rear longitudinal walls, equipped on their front longitudinal walls with resilient closure means (16-17), and equipped with foam linings (15) comprising recesses for the flush fitting of the valves and tubings of the connection site. According to the invention, the half shells (8a-8b) are articulated, via hinges (20) which are independent and spaced apart, on the thinned longitudinal edges of a rear transverse wall (22) integral with a slide (23) and mounted movably on the palette (5), whilst the length of this palette (5) is at least equal to the travel (C) which it is necessary for the slide (23) to cover in order to gain complete access to the protective site via the two half shells (8a-8b) in the open position. <IMAGE>
Patent DK-0539479-T3 (DK)
Inventor: KRENITSKY THOMAS ANTHONY
IPC: C07H19/20
Filed: 1991-07-18
Granted: 1997-08-25
Abstract: 6-Alkoxy derivatives of Ara-G, and pharmaceutically acceptable esters thereof, are described as being useful in tumor therapy. Novel pharmaceutically acceptable esters, their preparation and pharmaceutical formulations containing them are also disclosed.
Patent DK-0544784-T3 (DK)
Inventor: WALLER CLIVE GREGORY
IPC: G01F23/38
Filed: 1991-08-23
Granted: 1997-07-28
Abstract: PCT No. PCT/AU91/00386 Sec. 371 Date Feb. 19, 1993 Sec. 102(e) Date Feb. 19, 1993 PCT Filed Aug. 23, 1991 PCT Pub. No. WO92/03718 PCT Pub. Date Mar. 5, 1992.A sensor (1) is provided for sensing the entrainment of a fluid of low specific gravity in a fluid of higher specific gravity, particularly the entrainment of refrigerant gas in refrigerant liquid. The sensor (1) is typically installed into a higher pressure liquid supply line (24) of a refrigeration system (26). The sensor (1) has a differential float (16) including a float member (54) pivoted about a pivot (56) in a chamber (14) coupled to the supply line (24). The float member (54) has a specific gravity greater than the specific gravity of both of the fluids in which it operates. However, the location of the pivot (56) intermediate of the length of the float member (54) gives a net specific gravity for the differential float (16) which is less than the specific gravity of one of the fluids. Hence, the differential float (16) can withstand a high pressure operation, say at 2MPa, and can operate as a float for detecting the presence or absence of the fluid of lower specific gravity in the fluid of high specific gravity. The differential float (16) can also be used as gauge snubber (20) or to replace refrigerant capillary control tubes.
Patent DK-0511516-T3 (DK)
Inventor: BROEKER MICHAEL
IPC: C07K14/39
Filed: 1992-04-03
Granted: 1996-01-02
Abstract: The invention relates to schizosaccharomyces specific proteins and antibodies against them. These proteins and antibodies can be used for the identification of the yeast genus schizosaccharomyces.
Patent DK-0524478-T3 (DK)
Inventor: HALTERBECK WALTER
IPC: B65G15/54
Filed: 1992-07-07
Granted: 1995-12-27
Abstract: A wire-link band for process purposes, especially as a paper-machine covering, has a plurality of wire spirals (2, 12, 22, 32) which are arranged next to one another and engage into one another and which have head arcs (3, 13, 23, 33) receiving insert wires (5, 15, 25, 35) and turn legs (4, 14, 24, 34) connecting said head arcs. So that it has as small a thickness as possible, drags less air volume with it and is more elastic, the turn legs (4, 14, 24, 34) of at least one part of the wire spirals (2, 12, 22, 32) between two respective head arcs (3, 13, 23, 33) change at least once the flat sides (7, 8; 17, 18; 27, 28; 37, 38) of the wire-link band (1, 11, 21, 31). <IMAGE>
Patent DK-0548825-T3 (DK)
Inventor: GRIESBACHER THOMAS DR
IPC: A61K38/08
Filed: 1992-12-18
Granted: 1997-11-03
Abstract: The invention relates to the use of bradykinin-antagonists of the formula    R<1> - A - B - C - E - F - G - J - K - R<2>   wherein R<1> represents hydrogen, C1-C4-alkanoyl which can be substituted by mercapto, hydroxyphenyl, (4-benzoyl)phenoxy or represents (4-benzoyl)benzoyl-Lys; A represents D-Arg or D-Lys or stands for a direct bond; B represents Arg which can be substituted by NO2 or toluol-4-sulfonyl or represents Lys which can be substituted by toluol-4-sulfonyl or CO-NH-C6H5, or stands for a direct bond; C represents Hyp-Pro-Gly, Pro-Hyp-Gly, Pro-Pro-Gly or dehydroPro-Hyp-Gly; E represents Thi, Phe, Leu or Cha; F represents Ser or Cys; G represents D-Tic, D-Phe or D-Hyp substituted by C1-C4-alkoxy; J represents Tic, Aoc or Oic; K represents Arg or Ahx or stands for a direct bond; R<2> is hydroxy or amino; and the physiologically tolerable salts thereof for the treatments of acute pancreatitis, to pharmaceutical agents containing them and to the use thereof for the preparation of appropriate pharmaceutical compositions.
Patent DK-0599950-T3 (DK)
Inventor: YOUNG MICHAEL JOHN RADLEY
IPC: A61B17/56
Filed: 1992-08-24
Granted: 1997-12-01
Abstract: A tool for use in removing plastics material from a hole comprises a work surface adapted to contact the material. Piezo electric transducer means operatively connected through a work horn to the work surface cause it to vibrate ultrasonically and thereby to heat locally the plastics material. A cavity is adapted to received heated plastics material. The cavity is connected to a working zone adjacent the work surface. The work surface comprises a head flange and on a reverse side thereof a substantially annular cutting edge formed on one side of a conical face angled to the general direction of the tool.
Patent DK-0587084-T3 (DK)
Inventor: ELSNER HELMUT DR
IPC: B60B17/00
Filed: 1993-09-06
Granted: 1995-11-06
Abstract: The invention relates to a single wheel with wheel hub motor for rail vehicles, the wheel hub motor driving the single wheel either directly or with intermediate connection of a gear system and the drive unit (1) which is formed from motor and gear system, or the motor, being integrated into the single wheel. The object of the invention has consisted in finding a suspension of the wheel tyre (3) on the drive unit (1) which is compact and insensitive to the operating temperatures, occurring during travelling mode, of the drive unit (1) and to the heat radiation of the drive unit. This object is achieved according to the invention in that the wheel tyre (3) of the single wheel is arranged fixed in terms of rotation directly on the outer surface (2) of the drive unit (1) with intermediate connection of an elastic intermediate layer (4) and of a thermally insulating intermediate layer (5). <IMAGE>
Patent DK-0641224-T3 (DK)
Inventor: BURRELL ROBERT EDWARD
IPC: A01N59/16
Filed: 1993-05-19
Granted: 1999-05-25
Abstract: Anti-microbial coatings and method of forming same on medical devices are provided. The coatings are formed by depositing a biocompatible metal by vapor deposition techniques to produce atomic disorder in the coating such that a sustained release of metal ions sufficient to produce an anti-microbial effect is achieved. Preferred deposition conditions to achieve atomic disorder include a lower than normal substrate temperature, and one or more of a higher than normal working gas pressure and a lower than normal angle of incidence of coating flux. Anti-microbial powders formed by mechanical working to produce atomic disorder are also provided. The invention extends to other metal coatings and powders similarly formed so as to provide enhanced solubility.
Patent DK-0637317-T3 (DK)
Inventor: RUCHETON MARCEL
IPC: C07K14/765
Filed: 1993-04-22
Granted: 2003-12-01
Abstract: PCT No. PCT/FR93/00395 Sec. 371 Date Oct. 24, 1994 Sec. 102(e) Date Oct. 24, 1994 PCT Filed Apr. 22, 1993 PCT Pub. No. WO93/21228 PCT Pub. Date Oct. 28, 1993Method for purifying an aqueous solution of raw albumin wherein contaminant proteins are bound by chromatography to a stationary solid phase, preferably a particulate phase, the purified albumin solution being collected as an effluent, in which a neutral phase charged with at least one compound chosen from the group formed by compounds containing C3 to C8 alkyl radicals and compounds containing sulfate groups is used as the stationary phase.
Patent DK-0641965-T3 (DK)
Inventor: HELLMIG WINFRIED TEXTILINGENIE
IPC: F16L11/08
Filed: 1994-09-05
Granted: 1998-09-28
Abstract: The invention relates to a hollow tubular element which is exposed to high humidity levels and high temperatures, especially a steam-resistant hose or the like, a compensator and an air spring, the hollow element comprising an inner layer and outer layer of elastomeric material and an embedded single-ply or multi-ply reinforcement and also, if appropriate, one or more additional intermediate layers of elastomeric material, the reinforcement being a hydrolysis-resistant aramid.
Patent DK-0654415-T3 (DK)
Inventor: SCHUETZ UDO
IPC: B65D41/08
Filed: 1994-11-14
Granted: 1998-09-23
Abstract: The lid (2) of a sheet-metal container (1) for transporting and for storing liquids has a central filling aperture (3) which is enclosed by a nozzle (5) which is moulded out of the lid and is perpendicular to the lid surface (4). A ring (6) of plastic or metal with an external thread (7) is fitted onto the nozzle (5) and is pressed downwards against the lid surface (4) by the outwardly rolled upper edge (8) of the nozzle (5). The threaded ring (6) is secured against rotation on the nozzle (5) by positive-locking connections (not illustrated). Screwed onto the threaded ring (6) is a plastic closure lid (11), into which a disc-like insert (12) of special steel is pressed. Between the outer edge (13) of the lid insert (12) and an annular projection (14) thereof, an annular groove (15) is moulded into the insert to receive a sealing ring (16) with which the closure lid (11) is sealed off against the outwardly rolled upper edge (8) of the nozzle (5). <IMAGE>
Patent DK-0677112-T3 (DK)
Inventor: SMEEKENS JOSEPHUS CHRISTIANUS
IPC: A23L29/244
Filed: 1993-12-28
Granted: 2003-07-21
Abstract: The present invention relates to a method for obtaining transgenic plants showing a modified fructan pattern as compared to non-transformed plants, comprising the steps of: a) preparing a DNA construct comprising one or more fructosyltransferase genes, or modified versions thereof, being operably linked to a promoter sequence active in plants and a terminator sequence active in plants; b) transforming a plant cell with the construct; and c) regenerating a transgenic plant from the transformed plant cell. Preferably, the 5' untranslated region of the fructosyltransferase gene is modified such that the expression of the fructosyltransferase is not negatively affected. The DNA construct may also comprise a targeting sequence upstream from the fructosyltransferase gene for directing the fructosyltransferase to a specific plant tissue or plant cell compartment. The fructosyltransferases produced in the transgenic plants change the fructan pattern of the plants, thus leading to different plant performance due to altered sink-source relations and yield, increased tolerance for drought, cold or other stresses, higher dry matter content, better taste and storability, and improved nutritional value. The plants are also suitable for use as raw material for fructan production.
Patent DK-0664962-T3 (DK)
Inventor: SHIMIZU SATOKO
IPC: A23L1/00
Filed: 1995-01-25
Granted: 2002-01-14
Abstract: A batter for application to a material for frying contains edible oils and fats, water, an edible moisture holding material having a moisture holding amount of not less than 100g/ 100g by a centrifugal method under 2000 G, a foaming agent having foaming force of not less than 50 mm when measured as a 0.1 wt% aqueous solution at 25 DEG C by Ross-Miles test, and an emulsion stabilizer. A material for frying contains a filling and a multi-layer formed externally of the filling, the multi-layer containing a layer of the aforementioned batter. A frozen fried material for microwave cooking is prepared by frying the material for frying and freezing the fried material.
Patent DK-0723857-T3 (DK)
Inventor: SCHWELLING HERMANN
IPC: B30B15/00
Filed: 1995-12-07
Granted: 1999-10-25
Abstract: Both the top side of the front door frame and the door angle piece on the housing side lie one hand-width above the top of the baling plunger plate when this is fully raised. The two parts (2a,b) of the fill shaft flap are joined to the door frame by gas springs etc in addition to their hinges (G,S) so that the free flap part (2b) can only be swung vertical when the flap as a whole has been horizontalised. An end stop (3a,b) limits the swivel movement of the free flap part in relation to the bottom flap part. Adjustable end stops (4,5) at the flap join at the free ends of the spacer bars (6) are mounted to the inside of the door. The two parts of the flap are of the same size, with the part hinged to the baling press frame (1) slightly deeper than part for preference. The frame of the front is finished as a hollow rectangular profile.
Patent DK-0727418-T3 (DK)
Inventor: SHIGENO KAZUHIKO
IPC: C07D249/04
Filed: 1995-08-30
Granted: 1999-09-13
Abstract: This invention is to provide a process for preparing 1-amino-1,2,3-triazole represented by formula (III): <CHEM> comprising cyclizing glyoxal bishydrazone represented by formula (I):   <CHEM> by reaction with an aqueous hydrogen peroxide solution in the presence of a catalytic amount of a transition metal oxide represented by formula (II): MmOn wherein M represents a transition metal atom; and m and n, which may be the same or different, each represent an integer of 1 to 5.
Patent DK-0784677-T3 (DK)
Inventor: TSYRLOVA IRENA
IPC: C12N5/0789
Filed: 1995-09-29
Granted: 2004-08-02
Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
Patent DK-0792215-T3 (DK)
Inventor: VERHAEG JOHN MARIA
IPC: A61G5/04
Filed: 1995-11-14
Granted: 2001-05-28
Abstract: A vehicle such as a wheelchair having wheels by which the vehicle is propelled and steered and castors which support a proportion of the vehicle's weight, has its castors provided with biasing means which resists swivelling movement of the castors from the straight-ahead position thereby resisting an oversteer condition of the vehicle.
Patent DK-0776160-T3 (DK)
Inventor: CRANDALL BRADFORD G JR
IPC: A01P3/00
Filed: 1995-12-29
Granted: 2000-07-31
Abstract: Methods and compositions employing saponin as synergist in combination with a natural product, such as an aromatic aldehyde, are provided for controlling the colonization and/or growth of plant and animal pathogens, such as fungi, insects, arachnids and non-aquatic mollusks, on materials such as plants, plant parts and agricultural products before, during, after and/or processing. The invention finds use in treating agricultural crops for pathogenic organisms which colonize the surfaces of plant parts and tissues and controlling the level of toxic metabolites present in consumable products derived from plant materials, as well as reducing the health risk associated with their consumption. A method of employing saponin to kill nematodes is also provided.
Patent DK-0772569-T3 (DK)
Inventor: PHILIPPE ANDRE
IPC: B01J32/00
Filed: 1996-05-28
Granted: 2000-06-26
Abstract: PCT No. PCT/FR96/00799 Sec. 371 Date May 9, 1997 Sec. 102(e) Date May 9, 1997 PCT Filed May 28, 1996 PCT Pub. No. WO96/38378 PCT Pub. Date Dec. 5, 1996A process is provided for the catalytic removal of sulfur compounds, such as hydrogen sulfide and sulfur dioxide, out of a gas by contacting the gas with catalyst composition containing a silicon carbide support and a catalyst component, such as a salt or elemental state of a metal, such as titanium, zirconium, yttrium, lanthanum, uranium, lead, molybdenum, iron, cobalt, copper, nickel, zinc and cadmium and an oxide of a metal, such as uranium, lead, calcium, magnesium and cadmium. The process may be conducted at a temperature above or below the dew point of sulfur.
Patent DK-0865241-T3 (DK)
Inventor: WAGNER PETER
IPC: C12N9/00
Filed: 1996-12-02
Granted: 2002-12-23
Abstract: A method for preparing a dough or a baked product produced from the dough, including adding to dough or dough ingredients an L-amino acid oxidase or a benzylamine oxidase in an amount effective to improve gluten strength, stickness, or rheological properties of dough, or specific volume of the baked product. Further includes are bread- or dough-improving compositions including an L-amino acid oxidase or a benzylamine oxidase.
Patent DK-0939599-T3 (DK)
Inventor: RYDIN ANDERS
IPC: A47L9/14
Filed: 1997-11-20
Granted: 2003-03-03
Abstract: A dust separator for a vacuum cleaner, in which the bag is sealingly connected to a rigid member that screens-off an air-flow passageway through the vacuum cleaner and has an opening with which the bag connects. The screening member is separate from the bag. Mounted at the orifice of the bag is a flange which functions to prevent the bag from being drawn through the opening in the screening member in the direction of air flow through the vacuum cleaner. The flange can be collapsed to enable it to be passed through the opening in the screening member when the bag is full.
Patent DK-0900410-T3 (DK)
Inventor: CARCIA PETER FRANCIS
IPC: G03F1/00
Filed: 1997-05-09
Granted: 2003-10-06
Abstract: Attenuating embedded phase shift photomask blanks capable of producing a phase shift of 180 DEG  and having an optical transmissivity of at least 0.001 at selected lithographic wavelengths <400 nm comprise at least one layer of an aluminum compound and at least one component that is more optically absorbing than the aluminum compound at selected lithographic wavelengths <400 nm and are made by depositing at least one layer of an aluminum compound and at least one component that is more optically absorbing than the aluminum compound onto a substrate.