baber/WOPTO huggingface dataset:
Patent EA-201991285-A1 (EA)
Title: Резьбовое соединение для стальных труб
IPC: F16L15/04
Filed: 2017-12-27
Abstract: Предложено резьбовое соединение для стальных труб, которое предотвращает истирание на уплотнительных поверхностях во время скрепления, обеспечивая высокие показатели уплотнения по завершении скрепления. Ниппель (10) содержит носик (112), содержащий коническую направляющую поверхность ниппеля (112a) и уплотнительную поверхность ниппеля (113), содержащую коническую поверхность (113a). Муфта (20) содержит участок (22) приема носика, содержащий коническую направляющую поверхность (22a) муфты, уплотнительную поверхность (23) муфты, содержащую коническую поверхность (23a) и буферную поверхность (24). Угол конусности конической поверхности (113a, 23a) содержит второй угол конусности, который больше угла конусности конических направляющих поверхностей (112a, 22a). Резьбовое соединение (1) сконструировано для удовлетворения условиям Dp2>Db2>Dp1 и Lb2>Lp2. Буферная поверхность (24), расположенная между конической направляющей поверхностью (22a) и конической поверхностью (23a) муфты, имеет длину 0,75 мм или больше и расположена снаружи от воображаемой плоскости (V), как определено вдоль радиальных направлений.
Patent EA-202090583-A1 (EA)
Title: Композиции на основе антител против a33 и способы их применения в радиоиммунотерапии
IPC: A61K51/04
Filed: 2018-09-21
Abstract: Настоящее изобретение, в целом, относится к композициям на основе иммуноглобулинов (например, антителам или их антиген-связывающим фрагментам), которые могут связываться и нейтрализовать активность белка A33. Антитела согласно технологии по настоящему изобретению применимы в способах обнаружения и лечения A33-положительного рака у нуждающегося в этом субъекта.
Patent EA-202090640-A1 (EA)
Title: Получение твердых лекарственных форм, содержащих антитела, путем наслаивания раствора/суспензии
IPC: A61K9/16
Filed: 2018-09-11
Abstract: Изобретение относится к способу получения твердых лекарственных форм для немедленного и продолжительного высвобождения, содержащих антитела и их функциональные фрагменты, путем наслаивания раствора/суспензии, необязательно покрытые покрытием для замедленного высвобождения; твердым лекарственным формам, полученным с применением указанного способа; и применению твердых лекарственных форм при местном лечении в желудочно-кишечном тракте пациента.
Patent EA-202190551-A1 (EA)
Title: Водо- и энергосберегающие системы и способы получения теста маса варкой с известью
IPC: A23L13/40
Filed: 2019-08-06
Abstract: Описаны водо- и энергосберегающие системы и способы получения теста маса варкой с известью. Такие способы в основном включают добавление воды к ядру кукурузы в первой заданной пропорции, при этом ядро кукурузы имеет эндосперм, зародыш, перикарп и корневой чехлик в качестве компонентов. Ядро кукурузы кондиционируют в первом кондиционере в течение первого заданного периода времени, чтобы произошло поглощение влаги в пределах первого заданного диапазона. Ядро кукурузы обрабатывают известью. Ядро кукурузы варят в варочном аппарате в среде пара. После варки ядра кукурузы к ядру кукурузы добавляют воду во второй заданной пропорции, и ядро кукурузы кондиционируют во втором кондиционере в течение второго заданного периода времени для поглощения влаги в пределах второго заданного диапазона. Ядро кукурузы размалывают в одной или более мельницах.
Patent EA-202192566-A1 (EA)
Title: МУЛЬТИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА К EGFRxCD28
Filed: 2020-03-20
Abstract: В изобретении предложены мультиспецифические антитела, которые связываются с EGFR и CD28 (EGFRxCD28), а также антитела к EGFR. Такие антитела можно объединять с дополнительным терапевтическим агентом, таким как антитело к PD1. Также представлены способы лечения раковых заболеваний (например, рака, экспрессирующего EGFR) путем введения антител (например, и их комбинаций с антителами к PD1). Антитела к EGFRxCD28 по данному изобретению охватывают нацеленную на опухоль иммунотерапевтическую тактику лечения, объединенную с ингибированием PD-1. Эти биспецифические антитела связываются с опухолеспецифическим антигеном (ОСА) (EGFR) одним плечом и с костимулирующим рецептором CD28 на Т-клетках другим плечом. Комбинированная терапия ингибиторами PD-1 специфически усиливает внутриопухолевую активацию Т-клеток, стимулируя Т-клетки с фенотипом эффекторной памяти без системной секреции цитокинов при различных изогенных моделях и моделях ксенотрансплантата опухоли человека. Объединение этого класса костимулирующих CD28 биспецифических антител с клинически валидированным лечением антителом к PD-1 обеспечивает хорошо переносимую терапию антителами со значительно усиленной противоопухолевой активностью.
Patent ES-2178561-A1 (ES)
Title: Ozonisation process and device for the treatment of water contaminated with pesticides and other agriculturally-based organic polluting elements
Inventor: RODRIGUEZ FERNANDEZ-ALBA AMADE
IPC: C02F1/72
Filed: 2000-08-22
Abstract: Ozonisation process and device for the treatment of water contaminated with pesticides and other agriculturally-based organic polluting elements in which the volume of water is introduced into a reactor, where a mix of air and ozone bubbled through the water. During the aqueous phase certain pH conditions and concentrations of hydrogen peroxide are maintained, generating a high concentration of special radicals that produce oxidation of the contaminants. This way, the original contaminants and the intermediate products are eliminated, resulting in the complete mineralisation or reduction to small very oxygenated organic molecules, oxalic acid, formic acid in safe levels that allows subsequent reuse and dumping of the water.
Patent ES-2237225-A1 (ES)
Title: Reversible outer door, has latch and lock washer provided with closure assembly that is provided with lock, light bulb, shield, handle, cap and wing, and door panels provided with internal closure unit
Inventor: BLANCO MARTINEZ JOSE LUIS
IPC: E06B11/06
Filed: 2002-04-09
Abstract: The door has a male hinge provided with a self-lubricating bearing and a safety plug. An adjusting nut is located on a pole. A female hinge is located on a sheet. A latch and a lock washer are provided with a closure assembly. The closure assembly is provided with a lock, a light bulb, a shield, a handle, a cap and a wing. Door panels are provided with an internal closure unit.
Patent ES-2246151-A1 (ES)
Title: Set of derivatives of 2-(2-(pyridylmethylsulphinyl)-(benzimidazole) comprises products of selective oxidation of 2-(2-(pyridylmethylthio)-benzimidazole by e.g. alkali metal hypochlorite
Inventor: CAMPS RAMIREZ DE CARTAGENA HEL
IPC: C07D401/12
Filed: 2004-07-09
Abstract: Preparing 2-(2-pyridylmethylsulfinyl)benzimidazole derivative or its salt, solvate, and hydrate, comprises subjecting sulfide compound or its salt or solvate to an oxidation reaction with alkali metal hypochlorite and an alkali metal hydroxide where the solvent is an 1-6C alkyl ester. Preparing 2-(2-pyridylmethylsulfinyl)benzimidazole derivative of formula (I) or its salt, solvate, and hydrate, comprises subjecting sulfide compound of formula (II) or its salt or solvate to an oxidation reaction with alkali metal hypochlorite and an alkali metal hydroxide where the solvent is an 1-6C alkyl ester. R1, R2, R3 : H, 1-3C alkyl, 1-3C alkoxy which may optionally be substituted by one or more F, and 3-1-3C alkoxy-1-3C-alkoxy and R4 : a radical selected from H and 1-3C-alkoxy, which may optionally be substituted by one or more F. [Image].
Patent ES-2277703-A1 (ES)
Title: Transgenic tomato plants with acquired resistance to pseudomonas syringae pv. tomato
Inventor: VERA VERA PABLO
IPC: C12N15/52
Filed: 2004-07-28
Abstract: The bacterial spot caused by pathogen Pseudomonas syringae pv. tomato (P. s. tomato) is a devastating disease affecting tomato plants. The invention shows that the mere inhibition of the expression of gene Ep5C , coding an extracellular cationic peroxidase is sufficient to impart marked resistance to P. s. tomato . Said inhibition found in tomato plants provides a resistance with no need for activation of defence pathways currently described and controlled by salicylic acid and jasmonic acid. In addition the invention shows that Ep5C is repressed at the transcription level in healthy plants through the formation of a stable complex including proteins and one cis acting element identified within the 5' region of the gene promoter. Said complex is disabled in tissue infected with P. s. tomato and shows maximum expression in the gene. Thus Ep5C gene as well as its promoter provides a new genetic asset to develop plants resisting to be bacterial spot disease.
Patent ES-2284308-A1 (ES)
Title: Drum for laundry washing machines
Inventor: GRACIA BOBED ISMAEL
IPC: D06F37/06
Filed: 2005-03-08
Abstract: A drum for front-loading laundry washing machines or the like comprises a cylindrical perforated strip (1) for letting through the water flow, at least one crusher (3), a rear drum closing disk (5), and means for joining the disk to the strip in the area of the end of the crusher (3) nearest to the disk. The joining means comprise a rear joining support (7), a stop (9) opposite the joining support on the other side of the disk, and pressure means (11) which join the stop to the rear joining support, with the disk and part of the end of the crusher lying therebetween. The stop (9) is concave and its edges are at least in part in contact with the end of the crusher (3).
Patent ES-2307376-A1 (ES)
Title: Table-tennis net assembly with a winder
Inventor: D ESTAIS MATHIAS
IPC: A63B67/04
Filed: 2006-03-08
Abstract: The table-tennis net assembly comprises a net and two supports each having a structure that includes means for fastening it to a side of a table. At least one net support includes a hollow net-winder spool. An elongate resilient element is mounted inside said spool. A first end thereof is secured to the spool and a second end thereof is secured to the structure of the support. The resilient element forms part of the means for actuating the spool when it is pivotally mounted on the structure of the support, and/or part of means for actuating the fastener means. The fastener means are preferably of the clamp type comprising a top jaw for bearing against the top face of the side of the table and a bottom jaw for bearing against the bottom face. The resilient element contributes to moving said two jaws relative to each other.
Patent ES-2339911-A1 (ES)
Title: Isolation of multipotent hypophysary cells and in vitro differentiation thereof
Inventor: ALVAREZ VILLAMARIN CLARA
IPC: A61K35/12
Filed: 2008-11-25
Abstract: The invention relates to the isolation of multipotent hypophysary cells and to the in vitro differentiation thereof. The method is based on the presence in multipotent hypophysary cells of a receptor of the external face of the membrane, GFRa2+, which is not present in other cells of the hypophysis. The isolation method uses antibodies directed against said receptor and techniques permitting the separation of the cells to which said antibodies have bound. Once isolated, the cells may be maintained in culture without being differentiated or they may be differentiated in order to produce cells that produce hypophysary hormones or cells having a neurone phenotype. Consequently, the cells isolated using said method can be used for the production of hypophysary hormones. In addition, antibodies directed against GFRa2+, coupled to signalling molecules, can be used to detect the presence of multipotent hypophysary cells in any sample.
Patent ES-2377069-A1 (ES)
Title: Safety glasses for clean rooms and method for securing same
Inventor: BEHAR FREDERIC
IPC: A41D13/11
Filed: 2009-03-04
Abstract: Safety glasses for clean room, comprising two lateral fastening buckles enabling securing for the user of said glasses by manipulating only said fastening buckles and without having to manipulate the rest of said glasses.
Patent ES-2363399-A1 (ES)
Title: Catalyst for selective oxidation of hydrocarbons
Inventor: GARCIA GOMEZ HERMENEGILDO
IPC: B01J23/10
Filed: 2010-01-20
Abstract: The present invention relates to a solid catalyst that includes a metal-organic reticular pattern and an agent promoting the generation of radicals, to a method for obtaining said catalyst and to the use thereof as a catalyst in the selective aerobic oxidation reaction of hydrocarbons.
Patent JO-P20190052-A1 (JO)
Title: 5-[2-(pyridin-2-ylamino)-1,3-thiazol-5-yl]-2,3-dihydro-1 h-isoindol-1 -one derivatives and their use as dual inhibitors of phosphatidylinositol 3-kinase delta & gamma
Inventor: KARABELAS KONSTANTINOS
Filed: 2017-06-16
Abstract: There are disclosed certain novel compounds (including pharmaceutically acceptable salts thereof) (I) that inhibit phosphatidylinositol 3-kinase gamma (PI3K?) and phosphatidylinositol 3-kinase gamma (??3??) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.Fig.
Patent JO-P20200002-A1 (JO)
Title: Novel anti-human ceacam5 antibody fab fragment
Inventor: HIRAYAMA KAZUNORI
Filed: 2018-07-06
Abstract: NOVEL ANTI-HUMAN CEACAM5 ANTIBODY FAB FRAGMENT ABSTRACT Provided are an anti-human CEACAM5 antibody Fab fragment expected to be useful in the diagnosis of a cancer, particularly, the diagnosis of colorectal cancer, breast cancer, lung cancer, thyroid gland cancer or a cancer resulting from the metastasis thereof, and a diagnosis approach using a conjugate comprising the Fab fragment. The present invention provides an anti-human CEACAM5 antibody Fab fragment comprising a heavy chain fragment comprising a heavy chain variable region consisting of the amino acid sequence represented by amino acid positions 1 to 121 of SEQ ID NO: 2, and a light chain comprising a light chain variable region consisting of the amino acid sequence represented by amino acid positions 1 to 112 of SEQ ID NO: 4, and a conjugate comprising the Fab fragment
Patent SG-103319-A1 (SG)
Title: Ink cartridge for ink jet recording device
Inventor: HISASHI MIYAZAWA
IPC: B41J2/175
Filed: 2001-10-19
Abstract: An ink cartridge for an ink jet recording device, includes: a container having an ink supply port (14); at least two ink chambers partitioned in the container, one (16) being located substantially in an upper section and the other (3) being located substantially in a lower section; an ink suction passage connecting a bottom region of the lower section ink chamber to a bottom region of the upper section ink chamber; and a negative pressure generating mechanism provided to a flow passage connecting the upper section ink chamber to the ink supply port.
Patent SG-124239-A1 (SG)
Title: Close proximity weapon id system
Inventor: LIONG TAY SIEW
IPC: G06K7/00
Filed: 2002-01-23
Abstract: A Close Proximity Weapon ID System comprising an ID Chip, Airborne Scanner and Portable Scanner. The ID chip, attached to the surface of a store, upon receipt of a transmission of a certain format, shall respond by transmitting a low power, close range, coded signal containing its ID information and pre-programmed data parameters and the said ID chip derives its operating power from the received transmission. The airborne scanner, mounted on the aircraft, is able to establish communication with ail the ID chips within the range of operation and read their ID information and associated data parameters. The portable scanner, for use on the ground, communicates with the ID chips fitted onto the stores loaded on the aircraft or in ground storage areas.
Patent SG-126910-A1 (SG)
Title: Method and apparatus for using solution based precursors for atomic layer deposition
Inventor: CE MA
Filed: 2006-04-27
Abstract: A unique combination of solution stabilization and delivery technologies with special ALD operation is provided. A wide range of low volatility solid ALD precursors dissolved in solvents are used. Unstable solutes may be stabilized in solution and all of the solutions may be delivered at room temperature. After the solutions are vaporized, the vapor phase precursors and solvents are pulsed into a deposition chamber to assure true ALD film growth.
Patent TR-201921786-A1 (TR)
Title: Isil püskürtme yolu i̇le çok katmanli serami̇k yapilar üretmek i̇çi̇n bi̇r metot
Inventor: ŞEBNEM SAYGINER
IPC: C23C4/00
Filed: 2019-12-26
Abstract: Buluş, çok katmanlı seramik geniş bantlı telsizin anten kaportası üzerinde ısıl püskürtme kaplama malzemeleri ile imal edilmesine yönelik bir metottur. Birleştirilmiş yapı, biriken katmanların kalınlığına ve dielektrik sabitine bağlı olarak ayarlanmış olan RF saydamlığı yanıtı göstermektedir. Genişbant performansı için elzem olan ve kırılganlıkları nedeni ile üretilmesi zor olan mikron altı kalınlıktaki seramik katmanlar, hızlı ve otomatik bir işlem ile büyük ve karmaşık nesnelerde biriktirilebilmektedir.
Patent TR-202000842-A1 (TR)
Title: Bi̇r analog gürültü üreteci̇
IPC: H03F3/19
Filed: 2020-01-20
Abstract: Mevcut buluşla, çok tonlu sinyallerin yükseltilmesi sırasında ortaya çıkan arakiplenim bozulmasının önlenmesi için bir gürültü sinyali oluşturan bir analog gürültü üreteci geliştirilmektedir. Bahsedilen analog gürültü üreteci, en az bir karıştırma sinyali (Vm) oluşturan en az bir sinyal oluşturucuyu (O); çok tonlu bir giriş sinyalini (Vin) bahsedilen karıştırma sinyali (Vm) ile karıştırarak bir ara frekans sinyali (Vif) oluşturulmasını sağlayan en az bir birinci karıştırıcıyı (1); birinci karıştırıcı (1) tarafından oluşturulan ara frekans sinyalini (Vif) bahsedilen karıştırma sinyali (Vm) ile karıştırarak bir çıkış sinyali (Vo) oluşturulmasını sağlayan en az bir ikinci karıştırıcıyı içermektedir.
Patent AR-022429-A1 (AR)
Title: Latas metalicas micro-reclavadas
Filed: 2000-01-26
Abstract: La presente invencion se refiere a una lata, poseyendo una reclavacion, formada por proceso de micro-reclavacion a través del cual es posible producirlatas de fijacion de las tapas y fondos en cuerpos de latas por proceso de microreclavacion, formando una micro-reclavacion.Esta lata micro-reclavada puede serproducida por materiales de 0.16 mm de espesura o menor, con alta dureza DR8 o DR9, o aluminio u otros materiales, para hacer las tapas y fondos. Comoresultado de este micro-cierre, fue obtenida una significativa reduccion de las dimensiones en el gancho del cuerpo y de la tapa, en la extension de lareclavacion, cambiando la capacidad volumétrica de la lata.
Patent AR-023890-A1 (AR)
Title: METODO PARA LA APLICACIoN INTERMITENTE DE MATERIAL EN PARTICULAS.
IPC: A61F13/15
Filed: 2000-05-09
Abstract: La presente está dirigida a un método y aparato para aplicar intermitentemente material en partículas a un substrato; se provee un suministro de materialen partículas desde una fuente de suministro hasta una válvula que tiene una fase de aplicaciond e polvo y una fase de recirculacion; la válvula está dispuestapara la fase de aplicacion de polvo para permitir que el material en partículas pase a través de la misma y caiga libremente por lo menos sobre una porcion delsubstrato; la válvula estádi spuesta en la fase de recirculacion para evitar el suministro del material en partículas sobre el substrato y para retener elmaterial en partículas dentro de la válvula para ser transportado de nuevo a la fuente de suministro.
Patent AR-029368-A1 (AR)
Title: Una composicion farmaceutica para tratar enfermedades mediadas por una quimioquina y su uso para la manufactura de un medicamento util como antagonistas de los receptores de la il-8
IPC: A61K31/36
Filed: 2000-06-14
Abstract: Se refiere a una composicion para el tratamiento de una enfermedad mediada por una quimioquina, seleccionada del grupo constituido por malaria, restenosis, angiogénesis, aterosclerosis, osteoporosis, gingivitis, liberacion hematopoyética indeseada de células madre, y enfermedades causadas por virus respiratorios, herpesvirus, y virus de la hepatitis incluyendo, pero sin limitarse a ellos, el virus de la hepatitis B y hepatitis C, donde la quimioquina se une a un receptor alfa o beta de la IL-8 en un mamífero, que comprende una cantidad efectiva de un compuesto de la formula (1) donde W, W1, Z, R13, R14, y v tienen sus significados dados en la memoria descriptiva y a su uso para la manufactura de un medicamento en el tratamiento de enfermedades mediadas por la quimioquina interleuquina-8 (IL-8).
Patent AR-030673-A1 (AR)
Title: Anteojo electroactivo
IPC: C07K14/54
Filed: 2000-06-30
Abstract: Un anteojo electroactivo que comprende una lente electroactiva; un armazon que sostiene la lente electroactiva; un detector de cambio de vision acoplado a la lente electroactiva; y un interruptor manual en comunicacion con el detector de cambio de vision; en donde el interruptor manual se adapta para corregir el detector de cambio de vision y permitir un enfoque manual selectivo de la lente electroactiva.
Patent AR-027315-A1 (AR)
Title: Acidos 2-alquilo-5-halogeno-pent-4-enecarboxilicos y su preparacion
IPC: C07C57/52
Filed: 2001-01-29
Abstract: Compuestos de la formula (1) en la forma de sus racematos y enantiomeros, preferiblemente compuestos de la formula (1a) en donde R4 es C1-6 alquilo, Z escloro, bromo o yodo y X es -OH, cloruro, bromuro, o yoduro, o X forma un grupo éster con el susti tuyente carbonilo, así como tambén sales de los ácidoscarboxílicos. Los compuestos son valiosos como intermediarios para la preparacion de delta-amino-gama-hidroxi-omega-arl-alcano-carboxamidas que exhibenpropiedades inhibidoras de la renina y podría n ser utilizadas como agentes antihipertensivos en preparaciones farmacéuticas.
Patent AR-030499-A1 (AR)
Title: Un material laminado de empaque y contenedores de empaque producidos de los mismos
IPC: B32B27/10
Filed: 2001-08-27
Abstract: La invencion se refiere a un material laminar de empaque y contenedores de empaque para alimentos líquidos producidos a partir de los mismos. El material laminar de empaque (10) incluye una capa de papel o carton (11) y recubrimientos externos, herméticos a líquidos (13 y 14) sobre ambos lados de la capa de papel o carton (11). A fin de impartir al material laminar de empaque (10) una mayor rigidez y de tal modo fabricar contenedores de empaque con propiedades de agarre mejoradas, el material laminar de empaque (10) presenta una capa adicional (12) de poliolefina rellena con mineral entre la capa de papel o carton (11) y uno de los dos recubrimientos externos, herméticos a líquidos (14).
Patent AR-033722-A1 (AR)
Title: Dispositivo para suministrar liquidos
Filed: 2002-05-09
Abstract: Un dispositivo para el suministro de líquidos resulta particularmente adecuado para dosificar los agentes de limpieza que se emplean en los banos. El líquido fluye desde un reservorio (10) por una manga interna (34) de un conector (24) hasta un recipiente (18) hasta que el nivel del líquido alcanza la boca (60) de la manga interna (34). Se perfora una red (32) de modo tal que el espacio (14) en el recipiente (18) queda abierto a la atmósfera. El líquido es absorbido (18) por un capilar (46) que se forma entre la pared el recipiente (18) y el conector (24) y se suministra a una almohadilla porosa (6). El agua fluye entonces por dicha almohadilla (6) y la placa de apoyo (8) para dispersar el líquido por el inodoro.
Patent AR-035128-A1 (AR)
Title: Una formulacion de vacuna novedosa que consiste de una vacuna de adn y un virus inactivado
Filed: 2002-08-14
Abstract: Una formulación de vacuna para inmunización profiláctica o terapéuticas de vertebrados contra infecciones causadas por los virus de vertebrados. La vacuna contiene un mínimo de dos componentes uno de los cuales es una vacuna de desoxiribonucleótido (ADN) que comprende una molécula de ADN que codifica un polipéptido del virus y el otro componente consisten de una forma inactivada del virus. Lo propuesto puede aplicarse para desarrollar vacunas basadas en virus inactivado de bajo costo que contienen una cantidad mucho más baja de dicho virus que las vacunas similares conocidas actuales de la técnica anterior. Se describe también un procedimiento para producir la formulación de vacuna y la aplicación de dicha formulación.