baber/WOPTO huggingface dataset:
Patent EP-1030675-B1 (EP)
Inventor: SYKES MEGAN
IPC: A61K35/15
Filed: 1998-11-13
Granted: 2009-08-12
Abstract: The inventors have discovered that hematologic disorders, e.g., both neoplastic (hematologic cancers) and non-neoplastic conditions, can be treated by the induction of mixed chimerism using myeloreductive, but not myeloablative, conditioning. Methods of the invention reduce GVHD, especially GVHD associated with mismatched allogeneic or xenogeneic donor tissue, yet provide, for example, significant graft-versus-leukemia (GVL) effect and the like.
Patent EP-1057150-B1 (EP)
Inventor: BENSEN BENT THORNING
IPC: G08B21/20
Filed: 1998-12-22
Granted: 2002-10-16
Abstract: A method and apparatus for detecting a fluid; said method comprising providing one or more oscillators transmitting electromagnetic energy; providing one or more resonant circuits receiving electromagnetic energy from the oscillators; bringing the fluid and the one or more resonant circuits into contact with each other so that the receptions of electromagnetic energy of the resonant circuits are changed; and detecting changes of the transmissions of the oscillators by changes in one or more characteristics thereof upon the changes in the receptions of the electromagnetic energy of the resonant circuits; and use thereof for the detection of fluid levels, empty containers, and leak of fluids from containers and bodies containing said fluids; e.g. for monitoring collection of drain fluid from a human or for monitoring leak of fluid from a human suffering from urinary and/or fecal incontinence. Further, a method and apparatus for detecting a temperature, and sensing devices for sensing an external parameter, in particular a fluid or a temperature.
Patent EP-1037649-B1 (EP)
Inventor: GREENWALD RICHARD B
IPC: A61K38/00
Filed: 1998-12-14
Granted: 2009-09-30
Abstract: L'invention concerne des prodrogues doubles contenant des formes de transport à base de polymères. Ces prodrogues polymériques présentent, de préférence, la formule (I) dans laquelle L1 est une fraction de liaison bifonctionnelle; dans la formule (a) B étant H, un groupe partant, un résidu d'une fraction contenant amine, ou un résidu d'une fraction contenant hydroxy; Y1-4 sont, indépendamment O, S ou NR12; R1, R4, R9, R10 et R12 sont, indépendamment, sélectionnés dans le groupe constitué par hydrogène, alkyles C1-6, alkyles ramifiés C3-12, cycloalkyles C3-8, alkyles substitués C1-6, cycloalkyles substitués C3-8, aryles, aryles substitués, aralkyles, hétéroalkyles C1-6, hétéroalkyles substitués C1-6; R2, R3, R5, et R6 sont, indépendamment, sélectionnés dans le groupe constitué par hydrogène, alkyles C1-6, alkcoxy C1-6, phénoxy, hétéroalkyles C1-8, hétéroalkcoxy C1-8, alkyles substitués C1-6, cycloalkyles C3-8, cycloalkyles substitués C3-8, aryles, aryles substitués, aralkyles, halo-, nitro-, cyano-, carboxy-, carboxyalkyles C1-6 et carbonylalkyles C1-6; Ar est une fraction qui, lorsqu'elle est comprise dans la formule (I), forme un hydrocarbure aromatique multisubstitué ou un groupe hétérocyclique multisubstitué; (m), (r), (s), (t), (u) et (v) sont indépendamment zéro ou 1; (p) est zéro ou un entier positif; et R11 est un polymère sensiblement non antigénique. La première prodrogue se libère après clivage de la partie polymérique de la prodrogue double, et la molécule parent est libère ensuite rapidement in vivo, de préférence après une réaction d'élimination du 1,6 ou 1,4 benzyle. On décrit des procédés de préparation des composés ainsi que des méthodes de traitement.
Patent EP-0963326-B1 (EP)
Inventor: SMITH SIDNEY T
IPC: B31B50/64
Filed: 1998-12-18
Granted: 2003-04-09
Abstract: L'invention concerne un réservoir (10) comprenant une première paroi latérale (12) possédant une première couche (104) et une deuxième couche (102). La deuxième couche (102) recouvre une partie de la première couche (104), de manière à définir une zone de recouvrement (106). Une bride de scellement (108) s'étend depuis la première couche (104) vers l'extérieur de la zone de recouvrement (106). Une deuxième paroi latérale (14) est reliée à la première paroi latérale (12) le long de la bride de scellement (108) afin de définir une chambre intérieure (23) entre lesdites parois. La deuxième paroi latérale (14) et la bride de scellement (108) définissent une première structure stratifiée (120) possédant un premier nombre de couches le long de la bride de scellement (108). La zone de recouvrement (106) et la deuxième paroi latérale (14) définissent une deuxième structure stratifiée (122) possédant un deuxième nombre de couches. Ce deuxième nombre de couches est supérieur au premier nombre de couches. Le scellement de ce réservoir (10) consiste à placer les bords périphériques de la première et de la deuxième parois latérales (12, 14) afin qu'ils s'alignent les uns sur les autres, de sorte que la zone de recouvrement (106) est pratiquement placée au centre au-dessus de la deuxième paroi latérale (14), puis à appliquer une énergie de scellement au premier nombre de couches afin de définir un joint périphérique. Un autre réservoir (200) approprié à des utilisations médicales comprend un premier élément plan (218), un deuxième élément plan (222), un premier joint (224) et un deuxième joint (226). Le premier élément plan (218) est constitué par un matériau polymère à couches multiples et comporte, de plus, un premier substrat (238) et une première couche (246). Cette première couche (246) est située sur une partie du premier substrat (238) afin de définir séparément une première zone de recouvrement (258) et une première bride périphérique contiguë (262). Le deuxième élément plan (222) est constitué par un matériau polymère à couches multiples. Le premier joint (224) permet de fixer une partie de la première zone de recouvrement (258) au deuxième élément plan (222). Le deuxième joint (226) est éloigné du premier joint (224) et permet de fixer une partie de la première bride périphérique (262) au deuxième élément plan (222).
Patent EP-1042599-B1 (EP)
Inventor: RIES-MUELLER KLAUS
IPC: F02D41/26
Filed: 1998-12-17
Granted: 2003-08-13
Abstract: L'invention concerne un moteur à combustion interne destiné, en particulier, à un véhicule automobile et pourvu d'un appareil de commande. Cet appareil de commande peut assurer un certain nombre de fonctions selon des écarts temporels et/ou en fonction du nombre de tours du moteur à combustion interne. En outre, cet appareil de commande peut déterminer une grandeur (RA) représentant sa charge et une grandeur (N) représentant le nombre de tours du moteur à combustion interne. Cet appareil de commande peut également réduire le nombre des fonctions assurées lorsque la grandeur (RA) représentant sa charge est supérieure à une valeur seuil de charge (ASW1).
Patent EP-0962338-B1 (EP)
Inventor: ALBERTI ALBERTO
IPC: B60B1/04
Filed: 1999-01-20
Granted: 2003-04-23
Abstract: A wheel for a tyre (T) having a plurality of detachable spokes (30) to connect a rim (11) and a hub (40, 50). The rim (11) is integrally provided with two tubular sections (12, 13), each of them being arranged in the space comprised between one of the flanges (24, 25) retaining the beads of the tyre (T) and the wheel transversal center plane (p). In a preferred embodiment, the seats (32, 33) at the ends of the spokes (30), onto which the fastening nipples (31) are screwed, are extended along opposed walls (22, 23) of the said tubular sections (12, 13).     USE : Wheels preferably for tubeless tyres of motorcycles. ADVANTAGES : The wheel has a big sturdiness with only a minimum increase in weight with respect to conventional constructions and can be manufactured easily at a reduced cost.   <IMAGE>
Patent EP-0981258-B1 (EP)
Inventor: KAFFENBERGER RUEDIGER
IPC: H04J3/16
Filed: 1999-07-17
Granted: 2007-04-11
Abstract: The method involves transmitting the signals in a synchronous digital transfer mode and characterizing each with at least one identifying signal transmitted as an associated sequence of bytes. The transmitted identification signal is compared with an anticipated one in at least one component of the transmission path (10). The anticipated identification signal is converted into a number that is stored in the component, and is compared with a received identification signal that can be converted into a number, if appropriate.
Patent EP-0992771-B1 (EP)
Inventor: HIRT GUENTER
IPC: G01J1/10
Filed: 1999-08-16
Granted: 2005-10-26
Abstract: The method involves using a photodiode (48) to measure the signal level of the sensor for light reflected by a mark and different background regions at several wavelengths. The adjoining mark and background levels are determined for each wavelength, and the differences between the mark and background levels are calculated. The wavelength producing the largest level difference is selected to operate the sensor. An Independent claim is included for a light contrast sensor.
Patent EP-0967193-B1 (EP)
Inventor: YOSHIZAWA TORU
IPC: C07C29/32
Filed: 1999-09-08
Granted: 2002-11-27
Abstract: The invention provide a method for producing a fluoroalcohol of the following formula (1): H(CFR<1>CF2)nCH2OH (wherein R<1> represents F or CF3, when n=1; R<1> represents F, when n=2) comprising reacting methanol with tetrafluoroethylene or hexafluoropropylene in the presence of a free radical source, wherein the reaction mixture is subjected to distillation either in the presence of a base or after contact of said reaction mixture with a base.
Patent EP-1058868-B1 (EP)
Inventor: KASK KALEV
IPC: G06T19/00
Filed: 1999-02-26
Granted: 2004-10-20
Abstract: An apparatus is provided for resolving a collision between a first face and a second face of a sheet metal part represented by a 3-D model. The faces collide with one another when a 2-D model of a flat sheet metal part, designed on a CAD system, is folded into the 3-D model displayed on the CAD system. The apparatus comprises a detecting means, an analyzing means and an eliminating means. The detecting means is for detecting each collision between the faces which become adjacent in association with folding the 2-D model into the 3-D model. The eliminating means is for eliminating the collision by designing a 2-D model of a modified flat sheet metal part which can be folded without causing the collision.
Patent EP-0996971-B1 (EP)
Inventor: VERHAAR ROBERTUS D J
IPC: H01L21/8247
Filed: 1999-04-22
Granted: 2004-07-14
Abstract: Lors de la fabrication de circuits intégrés munis d'une mémoire non volatile intégrée, on fabrique généralement la majeure partie de la mémoire d'abord et on fabrique ensuite la logique CMOS dans une deuxième série d'étapes d'un processus CMOS ordinaire. En séparant ces étapes du processus, il est possible d'optimiser sensiblement la mémoire non volatile sans altérer la logique. La présente invention permet d'optimiser davantage ledit processus en ce que, en particulier pour la périphérie de la mémoire et en concomitance avec les transistors (21, 24, 27) de la mémoire, on fabrique des transistors qui peuvent supporter une tension plus élevée que les transistors de la logique. Dans le cas d'une EEPROM, chaque cellule de la mémoire est munie d'un transistor haute tension de ce type, qui fonctionne comme transistor de sélection (22, 24). Sauf en ce qui concerne l'implantation des puits N (5), les transistors haute tension à canal P sont en grande partie fabriqués suivant les mêmes étapes de processus que les transistors à canal P de la logique, de façon que le nombre d'étapes de processus reste limité. En ajoutant un seul masque, on peut munir le circuit d'une mémoire flash ou d'une mémoire programmable une seule fois (OTP).
Patent EP-1073767-B1 (EP)
Inventor: COULL JAMES
IPC: C12Q1/68
Filed: 1999-04-29
Granted: 2009-11-25
Abstract: The present invention relates to methods, kits and compositions suitable for the improved detection, quantitation and analysis of nucleic acid target sequences using probe-based hybridization assays.
Patent EP-1100538-B1 (EP)
Inventor: KEATING MARK T
IPC: C12Q1/68
Filed: 1999-05-12
Granted: 2007-08-08
Abstract: The genomic structure including the sequence of the intron/exon junctions is disclosed for KVLQT1 and KCNE1 which are genes associated with long QT syndrome. Additional sequence data for the two genes ARE also disclosed. Also disclosed are newly found mutations in KVLQT1 which result in long QT syndrome. The intron/exon junction sequence data allow for the design of primer pairs to amplify and sequence across all of the exons of the two genes. This can be used to screen persons for the presence of mutations which cause long QT syndrome. Assays can be performed to screen persons for the presence of mutations in either the DNA or proteins. The DNA and proteins may also be used in assays to screen for drugs which will be useful in treating or preventing the occurrence of long QT syndrome.
Patent EP-1183909-B1 (EP)
Inventor: VONLANTHEN ANDI
IPC: H04R25/02
Filed: 1999-06-16
Granted: 2011-02-23
Abstract: The hearing aid has a hook-shaped equipment body with a curved longitudinal axis and containing acoustic/electrical converters, electrical/acoustic converters and electronic units. The equipment body has a one-piece, at least partially tubular closed housing part which has a removable cover to complete a tube. The interior has holders for stacked insertion of units. An independent claim is also included for a method of assembling a hearing aid.
Patent EP-1068744-B1 (EP)
Inventor: DRESSEL JAN
IPC: H04W76/12
Filed: 1999-04-01
Granted: 2008-12-17
Abstract: A method for setting up a connection between a mobile radio network and a destination call number in a private communication network via a mobile radio network gateway. According to the inventive method, a call request is transferred from a mobile terminal to the mobile radio network gateway. The mobile radio network gateway begins by setting up a connection to the desired destination call number of the private network and, once this has been successfully achieved, subsequently sets up a connection to the mobile terminal.
Patent EP-1109733-B1 (EP)
Inventor: GRAFFAGNINO ROBERTO
IPC: C14B1/62
Filed: 1999-09-10
Granted: 2002-07-24
Abstract: Apparatus (1, 1') for the collection, distribution and storage of flexible laminar elements, in particular of industrial hides (P) during various phases of their production, including a first support unit (2) and a second hide handling unit (3), adapted to be operatively supported by the first unit (2), the first and second units being provided with releasable connecting elements (7, 8, 9, 10) to allow their transfer both jointly and separately, the second unit including two rotating cylinders (18, 21) with substantially parallel axes, and flexible conveying device (22) for loading, unloading and stocking hides (P), said conveying device being provided with two extremity portions each respectively fixed to one of the cylinders.
Patent EP-1116257-B1 (EP)
Inventor: KUWANA YASUHIRO
IPC: H01J9/14
Filed: 1999-08-24
Granted: 2010-10-06
Abstract: An aperture grille for cathode ray tube which includes a frame having at least one cutout portion. The aperture grille further includes a color screening electrode having a plurality of grille tapes which are held in tension in the frame thus causing at least one stress level in an associated region of the frame. The cutout portion is positioned adjacent the region so as to reduce the stress level.
Patent EP-1149044-B1 (EP)
Inventor: BOERS ARIE
IPC: B01F15/02
Filed: 1999-11-09
Granted: 2004-01-21
Abstract: A lid member for an original container of a liquid paint component. The lid member is usable with a system for dispensing the paint component from its original container into a paint receptacle according to a paint formula to form a liquid paint mixture. The lid member includes a base portion that is adapted to releasably engage an open top of the paint component container. The base portion has a pour spout through which the paint component can be dispensed and a movable cover element. The cover element is movable between a closed state, wherein the cover element covers the pour spout and the liquid paint component is prevented from being dispensed, and an opened state, wherein the pour spout is uncovered and the paint component can be dispensed from its original container and into the paint receptacle. An operating arrangement on the cover element is releasably engagable by an operating device of the dispensing system that moves the cover element between its closed and opened states. An alignment mechanism on the lid member aligns the paint component, while a latching arrangement of the lid member releasably secures the paint component container to the dispensing system.
Patent EP-1133674-B1 (EP)
Inventor: MICHEL DIETER
IPC: H01L31/0203
Filed: 1999-11-25
Granted: 2004-05-06
Abstract: L'invention concerne un bloc de composants optoélectroniques, notamment l'unité d'exploration (1) d'un dispositif de mesure de la position. Ce bloc de composants comprend une puce optoélectronique (100) dans laquelle sont intégrés des récepteurs optiques (12,13) et une source lumineuse (11). La puce optoélectronique (100) est fixée sur un support en verre (16) selon la technique de connexion par puces à protubérances et est mise en contact électrique avec des tracés conducteurs (17) du support en verre (16). Pour stabiliser la structure de connexion par puces à protubérances, une matière de remplissage sous-jacente (20) est introduite entre la puce optoélectronique (100) et le support en verre (16). Afin d'éviter les phénomènes de lumière parasite, l'espace (25) entourant la source lumineuse (11) et maintenu exempt de matière de remplissage sous-jacente (20).
Patent EP-1144233-B1 (EP)
Inventor: FRENTZ GEORG
IPC: B60T8/17
Filed: 1999-12-09
Granted: 2003-04-23
Abstract: L'invention concerne un système de freinage à assistance au freinage hydraulique, qui comporte une unité d'actionnement hydraulique (2) comprenant un réservoir hydraulique (3), une pédale de frein (4), un transmetteur de pression de freinage (5) et un simulateur de course de la pédale (6), une unité hydraulique (7) comprenant un générateur de pression, un dispositif de frein sur roue hydraulique (8) et un appareil de commande (9) pour coordonner les fonctions de l'unité d'actionnement (2), de l'unité hydraulique (7) et du dispositif de frein sur roue (8). Le simulateur de course de pédale (6) comporte un volume de refoulement (10) variable, relié au réservoir hydraulique (3) par l'intermédiaire d'une conduite hydraulique (11). Afin de mettre au point des freins électro-hydrauliques faibles avec des moyens simples, il est prévu une conduite de retour (12) entre le dispositif de frein sur roue (8) et le volume de refoulement. Il en outre prévu dans la conduite hydraulique (11), entre le réservoir hydraulique (3) et le volume de refoulement (10) du simulateur de course de pédale (6), un clapet de retour (13) qui peut être déplacé dans une position de fermeture bloquant la conduite hydraulique en cas de panne (lorsque le système de freinage est défectueux).
Patent EP-1109558-B1 (EP)
Title: Formulations de ranolazine a liberation lente
Inventor: WOLFF ANDREW A
IPC: A61K31/495
Filed: 1999-09-09
Granted: 2002-05-22
Abstract: La présente invention concerne une formulation de ranolazine à libération lente qui contient un mélange intime de ranolazine et un liant à dépendance du pH et partiellement neutralisé, et ce, de façon à former un film qui est sensiblement insoluble dans un milieu aqueux de pH inférieur à 4,5, et soluble dans un milieu aqueux de pH supérieur à 4,5. Cette formulation, qui convient à une administration biquotidienne de ranolazine, permet de réguler la cadence de dissolution de la ranolazine et de maintenir la teneur de ranolazine dans le plasma humain entre 550 et 7500 ng de base/mL.
Patent EP-1131110-B1 (EP)
Inventor: METZNER HUBERT
IPC: A61L24/00
Filed: 1999-11-16
Granted: 2006-03-29
Abstract: A tissue adhesive is described, which contains three separate components, i.e.,a stabilized, essentially fibrinogen-free protein preparation that is of storage-quality in liquid state and contains the blood coagulation factor XIIIa stabilized protein preparation that is of storage-quality in liquid state and contains fibrinogen. A chaotropic substance of less than 0.28 mol/liter was added to said protein preparation to avoid or reduce the aggregation of fibrinogen, anda preparation containing thrombin,which are provided in one packaging unit prepared to be used together.Furthermore, stabilized, frozen or lyophilized protein preparations containing fibrinogen and Factor XIII are described. Said protein preparations contain fibrinogen- and Factor XIII which remains stable for more than four weeks after defrosting or reconstitution, as well as one or more added chaotropic substances in a quantity of less than 0.28 mol/liter which prevents or reduces the aggregation of fibrinogen and contain inorganic salts of <100 mmol/liter, preferably <50 mmol/liter.
Patent IE-87081-B1 (IE)
Title: Manufacturing electrosurgical instruments
Inventor: LEWIS MEURIG JONES
IPC: A61B18/00
Filed: 2016-01-13
Abstract: A jaw member for an electrosurgical instrument is manufactured by providing a jaw housing (18) having a longitudinal jaw section (19), and an electrically conductive plate (1). The electrically conductive plate is placed into a mould, and a first flowable insulating material (15) is injected into the mould such that the flowable material (15) forms one or more stop members (16)that project a predetermined distance from the electrically conductive plate. the jaw housing (18) and the electrically conductive plate (1) are then placed into a second mould, and a second flowable material (25) is injected into the mould to secure the electrically conductive plate (1) to the jaw housing (18). <Figure 5>
Patent IE-87229-B1 (IE)
Title: Improved transport equipment
Inventor: ANDREW GLASS
IPC: E01F9/00
Filed: 2019-09-03
Abstract: A method of manufacturing an item of traffic equipment , comprises moulding a main body from an elastomeric material in a mould at an elevated temperature; removing the main body from the mould wherein the main body is at an intermediate temperature between the elevated moulding temperature and ambient temperature; placing a pre-formed piece of a thermoplastic paint sheet material in contact with a surface of the main body at the intermediate temperature; and applying heat to an outward facing surface of the preformed piece of thermoplastic paint sheet material so as to cause bonding between the contacting surfaces of the pre-formed piece of thermoplastic paint sheet material and the main body. An item of traffic equipment, comprises a main body formed from a moulded elastomeric material having a relief pattern on its outer surface defining at least one recess; and a pre-formed piece of thermoplastic paint sheet material of substantially the same shape and size as the at least one recess fitted within the at least one recess; wherein the a pre-formed piece of thermoplastic paint sheet material is directly bonded to the main body. <Figure 2>
Patent IT-1264200-B1 (IT)
Title: Convogliatore pneumatico per prodotti, in particolare pacchetti di  sigarette.
Inventor: GIGANTE ANTONIO
IPC: B65G51/03
Filed: 1993-09-01
Granted: 1996-09-23
Abstract: Convogliatore (1) pneumatico per prodotti: 2), in particolare pacchetti di sigarette, in cui i prodotti (2) stessi vengono fatti avanzare lungo un canale (15) di trasporto, il quale presenta, in sezione, dimensioni approssimanti per eccesso quelle dei prodotti (2), ed è provvisto di almeno una parete inferiore (19) provvista di una successione di elementi di iniezione (21) per un fluido pneumatico in pressione, e di almeno una parete superiore (18) provvista di una successione di passaggi (25) di scarico appena sufficienti a garantire la fuoriuscita del fluido pneumatico; gli elementi di iniezione (2) essendo orientati in una direzione presentante una componente parallela ad una direzione (24) di avanzamento dei prodotti (2) lungo il canale (15); di trasporto.(Figura 4).