baber/WOPTO huggingface dataset:
Patent AU-2018282466-A1 (AU)
Title: Esketamine for the treatment of depression
Inventor: CANUSO CARLA
IPC: A61P25/24
Filed: 2018-12-21
Abstract: The present invention provides methods of maintaining stable remission or stable response achieved by a patient with depression following administration of a therapeutically effective amount of esketamine during an initial administration 5 phase, comprising continuing administration of a therapeutically effective amount of esketamine for at least five months during a subsequent administration phase. The present invention also provides methods for the long term treatment of depression in a patient, comprising administering to the patient in need of the treatment a clinically proven safe and clinically proven effective therapeutically 10 effective amount of esketamine for at least six months. In some embodiments, the depression is major depressive disorder or treatment resistant depression.
Patent AU-2018312095-A1 (AU)
Title: Ultrahigh efficiency spray drying apparatus and process
Inventor: BEETZ CHARLES PERSHING
IPC: B01D1/00
Filed: 2018-08-04
Abstract: Ultrahigh efficiency spray drying systems and processes, utilizing induction of localized turbulence in a drying fluid flow stream to produce spray dried product, having particular utility for low temperature spray drying operations. A method of processing a spray dryable liquid composition to form a spray dried product includes: generating a spray of the spray dryable liquid composition; contacting the spray of spray dryable liquid composition in a spray drying contact zone with a stream of primary drying fluid; injecting pressurized secondary drying fluid into the stream of primary drying fluid in the spray drying contact zone at multiple loci thereof to provide localized turbulence at said multiple loci; and recovering the spray dried product from the spray drying contact zone. Systems of the present disclosure are effective in achieving high-rate production of dry powder spray dried products, with substantially reduced capital equipment costs, energy requirements, and operating expenditures.
Patent AU-2018314280-A1 (AU)
Title: Treatment of ophthalmic conditions such as macular degeneration, glaucoma, and diabetic retinopathy using pharmaceutical agents that eliminate senescent cells
Inventor: HOPKINS JILL
IPC: A61K38/13
Filed: 2018-08-13
Abstract: This invention is based on the discovery that many eye conditions associated with aging are mediated at least in part by cells bearing a senescent phenotype. Senescent cells accumulate with age, and express factors that contribute to the pathophysiology of age related conditions. The data show that in age-matched patients, the severity of age-related conditions correlates with the abundance of senescent cells, and that clearing senescent cells can help abrogate the condition. Small molecule drugs that remove senescent cells from affected tissue in the eye are provided as part of this invention that have special efficacy in treating ophthalmic conditions. They not only inhibit progression of the disease, they can also reverse some of the pathophysiology - such as neovascularization and vaso obliteration - that lead to vision loss. These senolytic agents have an appropriate dose and specificity profile to be effective in the clinical management of previously intractable ophthalmic conditions.
Patent AU-2018329551-A1 (AU)
Title: A truffle configured cosmetic article
Inventor: AKRIDGE ROBB
IPC: A61Q19/00
Filed: 2018-08-29
Abstract: A truffle configured cosmetic article which includes a protective outer shell, an inner volume of cosmetic and a capsule positioned in the cosmetic containing active ingredients. An appliance is adapted to receive the article, heat and blend the article to produce a warm skin formulation which can be applied by the user. The article is produced with the use of a mold. A combination of wax and coconut oil is melted and applied to most of the interior surface of the mold, defining a volume into which a cosmetic is applied as well as a capsule additive. The article is then sealed with additional wax and coconut oil material. The article is then released and ready for use in the appliance or to be wrapped.
Patent AU-2018338728-A1 (AU)
Title: Rescue of central and peripheral neurological phenotype of Friedreich's Ataxia by intravenous delivery
Inventor: SAH DINAH WEN-YEE
IPC: C12N15/113
Filed: 2018-09-28
Abstract: Provided herein is an adeno-associated virus (AAV) particle comprising a capsid and a viral genome, wherein said capsid delivers the AAV particle to a nervous system, and wherein said viral genome comprises a polynucleotide sequence encoding Frataxin and one or more microRNA binding sites. Also, provided herein is a method for treating, ameliorating, and/or preventing a disorder in a subject stemming from a loss or partial loss of frataxin protein in the subject, wherein the method comprises: administering to the subject a therapeutically effective amount of a composition comprising an AAV particle comprising a capsid and a viral genome, wherein said capsid delivers the viral genome to a nervous system, and wherein said viral genome comprises a polynucleotide sequence encoding Frataxin and one or more microRNA binding sites, as described herein.
Patent AU-2018344100-A1 (AU)
Title: Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof
Inventor: QI YUXIN
IPC: C07C211/00
Filed: 2018-03-06
Abstract: The present application relates to methods of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or its derivatives in an environment-friendly way. The method uses L-glutamic acid as a starting material, which is first subjected to esterification reaction in the presence of an acidic reagent, and then reacted successively with 2-haloacetate and N-protecting agent, or with N-protecting agent and 2-haloacetate under a basic condition to obtain compound IV; then, the obtained compound IV is subjected to intramolecular condensation into a ring under the action of a strong base to obtain N-protecting group piperidine-5-one-2S-carboxylate (V). The obtained compound V is used for preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid (or ester thereof) through one of the routes below: Route 1: compound V is subjected to removal of protecting group, condensation with benzyloxyamine hydrochloride, imine reduction-chiral resolution, neutralization, and hydrolysis; Route 2: compound V is subjected to hydrolysis, removal of protecting group, condensation with benzyloxyamine hydrochloride, imine reduction-chiral resolution, and neutralization; Route 3: compound V is subjected to condensation with benzyloxyamine hydrochloride, imine reduction-chiral resolution, removal of protecting group, neutralization, and hydrolysis. All of the routes above may be implemented by a "one-pot" method.
Patent AU-2018386524-A1 (AU)
Title: Oligonucleotides comprising a phosphorodithioate internucleoside linkage
Inventor: BLEICHER KONRAD
IPC: C07H21/00
Filed: 2018-12-21
Abstract: The present invention relates to an oligonucleotide comprising at least one phosphorodithioate internucleoside linkage of formula (I) (I) as defined in the description and in the claim. The oligonucleotide of the invention can be used as a medicement.
Patent AU-2018392008-A1 (AU)
Title: Gripping apparatus and devices for plugging of pipes, orifices or connecting
Inventor: SUE TRACY
IPC: F16L55/11
Filed: 2018-12-21
Abstract: The disclosure relates to a gripping apparatus for use in connecting to a pipe wherein the pipe defines an inside radius, having: a body of the gripping apparatus; a wedge cone mounted on the body; at least one discrete gripping device slidably engaged with the wedge cone; and an actuation-retraction mechanism configured to actuate the at least one discrete gripping device. The actuation-retraction mechanism of the gripping apparatus may be a collective actuation-retraction mechanism in an exemplary embodiment. In further disclosed alternative exemplary embodiments, the actuation-retraction mechanism of the gripping apparatus may be a plurality of individual actuation-retraction mechanisms.
Patent AU-2019200377-A1 (AU)
Title: Down regulating gene expression in insect pests
Inventor: BEGHYN MYRIAM
IPC: C12N15/82
Filed: 2019-01-21
Abstract: ll:\aar\Interwovn\NRPortbl\DCC\AAR\12560066_l.docx-4/012017 The present invention relates to genetic control of infestation by insect pest species, particularly prevention and/or control of pest infestation of plants, using interfering ribonucleic acid (RNA) molecules. Compositions and combinations containing the interfering RNA molecules of the invention for use in topical applications, for example in the form of insecticides.
Patent AU-2019200539-A1 (AU)
Title: Predictive header height control system
Inventor: REED DANIEL
IPC: A01D41/14
Filed: 2019-01-29
Abstract: An agricultural vehicle comprises a chassis, a header carried by the chassis, an actuator system including a plurality of actuators linked to a frame of the header and configured to adjust an orientation of the header, a GPS device configured to output a GPS position of the vehicle, and a controller. The header includes a frame and one or more sensors carried by the frame. The controller is electrically coupled to the one or more sensors, the actuator system, and the GPS device. The controller is configured to receive from a memory a final orientation of the header associated with a GPS position at a second location on a last pass that is closest in distance to a GPS position at an upcoming location on the current pass, and activate one or more actuators to re-orient the header before the vehicle arrives at the upcoming location. CD cn co co CD CD Ir CN m < CD CD co elo r-E C:) c:o LO Cc CD oo -01 Nl 0 oil0 CD LO LO CD CD 04 LO C::) 0 c::) C") LL-1 cy') 'r.-
Patent AU-2019201226-A1 (AU)
Title: Rf tag antenna and method of manufacturing the same, and rf tag
Inventor: SUGIMURA SHIRO
IPC: H01Q13/08
Filed: 2019-02-21
Abstract: - 55 [Problem to be Solved] To provide an RF tag antenna capable of improving readability and a method of manufacturing the same, and an RF tag. [Solution] An RF tag antenna 10 according to an embodiment includes a first insulating substrate 40 having a first principal surface and a second principal surface, a first waveguide device 20 provided on the first principal surface, a second waveguide device 30 provided on the second principal surface, a power feeding part 50 electrically connected to the second waveguide device 30 at one end thereof, and a short-circuit part 60 electrically connected to the first waveguide device 20 at one end thereof and to the second waveguide device 30 at another end thereof, the first insulating substrate 40, the first waveguide device 20, the second waveguide device 30, the power feeding part 50 and the short-circuit part 60 form a plate-shaped inverted-F antenna that receives a radio wave transmitted from a reader, and an inductor pattern L formed by the first waveguide device 20, the short-circuit part 60, the second waveguide device 30 and the power feeding part 50 and a capacitor 93 formed by the first waveguide device 20, the second waveguide device 30 and the first insulating substrate 40 form a resonant circuit that resonates in a frequency band of the radio wave.
Patent AU-2019202190-A1 (AU)
Title: Digital transport of data over distributed antenna network
Inventor: ZHUANG QIANQI
IPC: H04H20/76
Filed: 2019-03-29
Abstract: DIGITAL TRANSPORT OF DATA OVER DISTRIBUTED ANTENNA A system for transporting data in a Distributed Antenna System (DAS) includes at least one Digital Access Unit (DAU) and a plurality of Digital Remote Units (DRUs) coupled to the at least one DAU. The plurality of DRUs are operable to transport signals between the plurality of DRUs and the at least one DAU. The at least one DAU includes: a data transport coder comprising: a framer, an encoder, a scrambler, and a serializer and a data transport decoder comprising: a deserializer, a decoder, a descrambler, a frame synchronizer, and a deframer.
Patent AU-2019203045-A1 (AU)
Title: Methods and systems for converting body movements to games inputs
Inventor: SONGHORI ARMIN
IPC: A61B5/103
Filed: 2019-04-30
Abstract: The present invention relates to a method and system for converting body movements to games inputs are described. The method includes the steps of receiving data relating to spatial orientation of a plurality of IMU sensors into a processing apparatus, and then comparing, in a processing apparatus, the relative spatial movement of a pair of IMU sensors disposed about a movable joint to produce a representation of the movable joint movement for input into a game engine plugin. The system includes a pair of sensors disposed in use about a movable joint, the pair of sensors wirelessly connected to a processing apparatus for comparing the relative spatial movement of the pair, to produce a representation of the movable joint movement for input to a game engine plugin.
Patent AU-2019206551-A1 (AU)
Title: Polishing or grinding pad with multilayer reinforcement
Inventor: TCHAKAROV TCHAVDAR V
IPC: B24B7/18
Filed: 2019-01-10
Abstract: A polishing or grinding pad (21; 121; 221) with a multilayer reinforcement (41; 43; 141; 143; 241; 243) is provided. In one aspect, a floor polishing or grinding pad assembly employs a flexible pad (31; 131; 231), at least two reinforcement layers or rings with different characteristics, and multiple floor-contacting tools (71; 171; 271) such as abrasive disks. In another aspect, a workpiece polishing or grinding pad assembly includes a flexible and rotatable pad, a polymeric reinforcement layer (43; 143; 243) coupled to the pad and a metallic reinforcement layer (41; 141; 241) to which are coupled abrasive tools. In yet another aspect, a floor-facing reinforcement is more flexible than a pad-facing reinforcement which is more rigid.
Patent AU-2019216976-A1 (AU)
Title: Virtual and augmented reality telecommunication platforms
Inventor: ORR ERAN
IPC: G06F3/01
Filed: 2019-02-11
Abstract: Provided herein are clinical evaluation and treatment as well as training protocols in virtual or augmented reality that create fully immersive environments, which enable real-time rendering for communication, specifically telecommunication, between two or more parties. In various embodiments, a virtual environment is provided to a first user at a first location. A first set of data comprising positional data of the first user is provided to a second user (
Patent AU-2019223520-A1 (AU)
Title: Game management system
Inventor: SHIGETA YASUSHI
IPC: A63F9/00
Filed: 2019-02-15
Abstract: Provided is a game management system which reliably grants points corresponding to an amount bet by a player. A game management system (100) for managing a casino game carried out in a casino facility is provided with a gaming table (4) for carrying out a game using gaming token money (9), a camera (2) which captures an image of the gaming token money (9) that has been bet, and obtains an image, a control device (50) which identifies the amount bet at each player position on the gaming table (4) on the basis of the position, type, and quantity of the gaming token money (9) in the image, a reader/writer device (5) which identifies players participating the game at each player position on the gaming table (4), and a point processing unit (612) which associates a member ID of each player identified by the reader/writer device (5) with the amount bet at each player position, identified by the reader/writer device (5), and stores the same in a recording device (62), wherein the point processing unit (612) has a configuration provided with a function of granting to each player identified by the reader/writer device (5) points corresponding to the amount bet by the player.
Patent AU-2019240569-A1 (AU)
Title: Signage layered display monitors
Inventor: WINSTON ERIC
IPC: A63F13/00
Filed: 2019-09-30
Abstract: A gaming signage system may include one or more movable displays. One or more movable displays may present first visual effects while the one or more moveable displays are in a first configuration in which at least one game feature presentation device is not viewable. In response to a trigger event indication (which may correspond to a base game event), the movable display(s) may move to a second configuration and reveal the game feature presentation device. The game feature presentation device may be used to present a bonus feature and/or to present a different aspect of the base game. Alternatively, at least a portion of a movable display may be hidden when in a first configuration. At least the portion of the movable display(s) may present a bonus feature and/or a different aspect of the base game when in the second configuration. 11664824_1 (GHMatters) P11181O.AU 250---4 15
Patent AU-2019252287-A1 (AU)
Title: Facilitating quality of service flow remapping utilizing a service data adaptation protocol layer
Inventor: LIU FEILU
IPC: H04W28/02
Filed: 2019-04-11
Abstract: Aspects directed towards Quality of Service (QoS) flow remapping are disclosed. In an example, upon detecting a mapping reconfiguration of a first QoS flow from a first data radio bearer (DRB) to another DRB, a Service Data Adaptation Protocol (SDAP) control protocol data unit (PDU) is generated indicating that a final SDAP data PDU associated with the first QoS flow has been transmitted on the first DRB. The SDAP control PDU is then transmitted via the first DRB. In another example, upon detecting a mapping reconfiguration of a first QoS flow from a first DRB to another DRB, an end marker parameter is set in an SDAP header of a first SDAP data PDU received from an upper layer after the mapping reconfiguration indicating that the first SDAP data PDU is a final SDAP data PDU associated with the first QoS flow transmitted on the first DRB.
Patent AU-2019252662-A1 (AU)
Title: Compositions and methods for stem cell transplant
Inventor: BEARD BRIAN
IPC: C12N15/63
Filed: 2019-04-11
Abstract: The present invention provides systems and methods for manufacturing and using gene corrected stem cells for gene therapy. In particular, herein provided are methods for treating Fanconi anemia in which a subject's stem cells are selected by a combination of high stringency CD34+ selection and low stringency CD34+ selection, genetically modified using a gene therapy vector encoding a FANC protein or a gene editing system, and administered to the subject.
Patent AU-2019262182-A1 (AU)
Title: Systems and methods for an embedded browser
Inventor: FLECK CHRISTOPHER
IPC: G06F9/54
Filed: 2019-05-03
Abstract: The present disclosure is related to systems and methods of monitoring data of a network application. An embedded browser of a client application on a client device may initiate a request to access a network application hosted on a server. The client application may, responsive to the request, establish a secure session to communicate data of the network application to the client application for rendering in a display region of the embedded browser. The client application may decrypt the data communicated via the established secure session to monitor the network application.
Patent AU-2019267711-A1 (AU)
Title: Nanofiber-hydrogel composites for cell and tissue delivery
Inventor: REDDY SASHANK
IPC: A61L27/48
Filed: 2019-05-09
Abstract: A soft tissue device can incorporate a composite material comprising a gel and at least one nanostructure disposed within the gel. A soft tissue device can further incorporate biologically active materials such as cells, tissues. A method for healing a soft tissue defect while promoting soft tissue regeneration can include applying a soft tissue device to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a soft tissue device for use in healing soft tissue defects can include providing a gel, disposing nanofibers within the gel, and a biologically active material.
Patent AU-2019275194-A1 (AU)
Title: Method for measuring a tree trunk, and a harvester
Inventor: LUNDGREN KARL
IPC: G01B5/00
Filed: 2019-04-12
Abstract: A harvester (1), comprising a harvester aggregate (2) for felling, trimming and preparing tree trunks, a first measuring device (I) provided in connection with the harvester aggregate (2) for measuring of at least one dimension of a tree trunk. The harvester comprises a second measuring device (II) for measuring a feature of the first measuring device, whereby said feature is an attribute reflecting the capability of the first measuring device to measure said dimension correctly, and a control unit (11) configured to make a comparison between an actual value (a) of the measured feature and a target value (β) of said feature, whereby the target value is indicative of a state of the first measuring device, where its measurement of said dimension is considered to be correct.
Patent AU-2019280914-A1 (AU)
Title: Plant growth regulator system
Inventor: WIKELEY PHILIP SIMON
IPC: A01N57/20
Filed: 2019-06-07
Abstract: The invention relates to a plant growth regulator system comprising a synergistic combination of prohexadione and ethephon. The invention further relates to a method for treating plants with at least prohexadione and ethephon, wherein a water based spraying liquid is sprayed on plants, wherein the liquid comprises water and suitable amounts of prohexadione and of ethephon, wherein the amount of prohexadione is between 20 and 400 g per hectare, and wherein the amount of ethephon is between 0 and 1000 g/ha. The plants are rape seed, flax or cereal crops. Cereal can be barley, oat, wheat, rye, triticale, grain or corn. The combination shows substantial synergistic effects on stem reduction, and therefore reduce risk of lodging and improve yield.
Patent AU-2019285491-A1 (AU)
Title: GLP-1 receptor agonists and uses thereof
Inventor: ASPNES GARY ERIK
IPC: A61P3/10
Filed: 2019-06-11
Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza- 5-aza-, and 7-aza-benzimidazoles as GLP-1 R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof (Formula I).
Patent AU-2019295330-A1 (AU)
Title: Surgical kit and method
Inventor: BEVERLAND DAVID
IPC: A61B17/17
Filed: 2019-04-29
Abstract: A surgical kit and method for performing a controlled resection of the neck of a femur during a hip replacement procedure. The kit includes a mounting portion. The mounting portion includes guide holes for inserting guide pins into the femoral head while the mounting portion is located on an anterior aspect of the femoral head. The kit also includes a body portion connected to the mounting portion. The body portion includes an opening for mounting the body portion on an intramedullary pin. The kit also includes a resection guide including guide holes having the same layout as the guide holes of the mounting portion, to allow the resection guide to be mounted on the anterior aspect of the femoral head with the guide pins inserted into the femoral head for positioning a resection plane indicator of the resection guide with respect to the neck of the femur.