baber/WOPTO huggingface dataset:
Patent EP-3650468-A1 (EP)
Title: Targeting metastasis stem cells through a fatty acid receptor (cd36)
Inventor: AZNAR BENITAH SALVADOR
IPC: A61K39/00
Filed: 2016-09-29
Abstract: Targeting metastasis stem cells through a fatty acid receptor. The disclosure provides the use of blockers or inhibitors of CD36 activity or expression for the treatment of oral squamous cell cancer (OSCC), particularly for the treatment of generated metastases and for diminish is generation from primary tumours. Apart from shRNAs, anti-CD36 antibodies are provided as blockers or inhibitors, especially those that block the binding of CD36 to oxidized LDL and fatty acids and their incorporation into cells, because the promotion of their transport is indicated as the mechanism by which CD36 promote metastases dissemination and growth. Also provided is a method for identifying candidates to anticancer agents, particularly for OSCC metastasis, among those that promote in CD36+ cells, in vivo or in vitro, effects associated to CD36 depletion or blocking such as decrease of growth accumulation of lipid droplets and decrease of size in the case of metastases.
Patent EP-3667650-A1 (EP)
Title: Electronic panel for road signaling, application process and its uses
Inventor: MAGALHÃES SEMANAS JOSÉ ARMANDO
IPC: E01F9/615
Filed: 2019-12-12
Abstract: A road signalling electronic panel (1), its application process and respective uses, for installation on a support surface in a predetermined signalling direction, comprising: signalling face comprising a plurality of light emitters arranged in a matrix along lines and columns of said emitters; a panel fixing structure to the support surface by the panel part opposite to that of the signalling face; wherein said fixing structure is configured to secure the panel such that the signalling face and support surface are arranged at a predetermined angle, herein referred to as installation angle (α, A); wherein said light emitters are coupled to the panel forming a predetermined angle between the light projection direction of the emitters and said signalling face, referred to herein as projection angle (β); wherein, in a section perpendicular to said support surface and parallel to the signalling direction, said installation (α, A) and projection (β) angles are interior alternating angles relative to the transverse formed by the signalling face; wherein the projection angle is greater than the installation angle.
Patent EP-3703331-A1 (EP)
Title: Systems and methods for network management
Inventor: LOISEAU FRANCOIS
IPC: H04L29/06
Filed: 2019-02-27
Abstract: Methods and systems are described for connecting to network services on a private network. A gateway device may coordinate communications between a client device on a public network and a host device on a private network. The client device may request to access the host device via the gateway device. The gateway device may authenticate the client device. The gateway device may transcode communications between the client device and the host device, thereby masking the address of the client device and the host device. The gateway device may maintain two different encryption methods between the client device and the gateway device, and the gateway device and the host device.
Patent EP-3839870-A1 (EP)
Inventor: FERNANDES LUIS FILIPE SANCHES
IPC: G06Q50/02
Filed: 2019-12-20
Abstract: The present invention refers to a methodology to determine the locations that are favourable to the implementation of systems for rainwater harvesting, within hydrographic basins, for agricultural and forestry applications, namely irrigation and fire fighting. The methodology consists in a data acquisition stage, that is, the survey of the physical characteristics of the hydrographic basins being studied, the socioeconomic and ecological data thereof, whereby all data is registered in georeferenced thematic maps; followed by a space evaluation stage, where a spatial multicriteria analysis is carried out, based on the georeferenced maps and on a range of dynamic and adaptive considerations according to the scenario in question; at the end a classification of the possible locations for rainwater harvesting systems is obtained, assuring an irrigation by gravitational flow as well as a smaller environmental impact.
Patent EP-3749236-A1 (EP)
Inventor: MÜLLER ANDREA
IPC: A61B17/32
Filed: 2019-02-06
Abstract: Disclosed is a system to be used for transmitting ultrasonic vibration, the system comprising a sonotrode (1) designed to vibrate in a stationary wave comprising at least one node position between the distal end (1.1) and the proximal end (1.2) of the sonotrode, and a guide shaft (2) with a through opening (3). During operation the sonotrode (1) extends through the through opening (3) of the guide shaft (2) and the distal end (2.1) of the guide shaft (2) is situated on a distal side of the most distal node position (Nl) of the sonotrode (1). The sonotrode (1) and the guide shaft (2) are adapted to each other for radial clearance (RC) between the sonotrode (1) and the guide shaft (2) to be a minimum (RC1) for a sonotrode portion (1.3) comprising the most distal node position (Nl).
Patent EP-3765499-A1 (EP)
Inventor: STEINIGER SEBASTIAN C J
IPC: A61K39/395
Filed: 2019-01-18
Abstract: The present disclosure encompasses novel anti-NGF antibodies, antigen binding proteins and polynucleotides encoding the same. The disclosure further provides use of the novel antibodies, antigen binding proteins and/or nucleotide of the invention for the treatment and/or prevention of NGF related disorders, particularly in for the management of pain.
Patent EP-3777452-A1 (EP)
Inventor: BROWN RUTH
IPC: H04W76/10
Filed: 2019-03-27
Abstract: A method of establishing bearers for a device in a wireless communication network, comprising: collecting for the device data over a period of time from communication sessions the device participates in, at least some of the communication sessions being supported by a default bearer and a dedicated bearer; calculating from the collected data a likelihood a dedicated bearer will be established for the device at one or more different times values, and predicting the dedicated bearer will be established for the device at a time value if the likelihood of establishment at that time value exceeds a specified threshold; and initiating establishment of the dedicated bearer to establish the dedicated bearer for the predicted time value.
Patent EP-3768368-A1 (EP)
Inventor: CLEMENS WILLIAM J
IPC: A61N1/05
Filed: 2019-03-20
Abstract: A distal electrode of an electrode assembly, for example, employed by an implantable medical electrical lead device, extends distally from a distal terminal end of a sleeve of the assembly; and the sleeve, which defines a longitudinal axis of the assembly, includes a plurality of channels that provide fluid communication between a steroid eluting component, which is seated in an external groove of the sleeve, and an area distal to the distal terminal end of the sleeve. Floors of some or all of the sleeve channels may angle toward the longitudinal axis of the assembly, being closer to the axis at the distal terminal end of the sleeve.
Patent EP-3776701-A1 (EP)
Inventor: STEINBACH ANDREW J L
IPC: C22C5/04
Filed: 2019-03-27
Abstract: La présente invention concerne un matériau de catalyseur pour la réduction d'oxygène nanoporeux comprenant au moins 90 collectivement de Pt, Ni, et Ta. Le matériau de catalyseur pour la réduction d'oxygène nanoporeux est utile, par exemple, dans des ensembles électrodes à membrane de pile à combustible.
Patent EP-3788107-A1 (EP)
Title: High strength additive manufactured articles
Inventor: ELLEITHY RABEH
IPC: C08L69/00
Filed: 2019-04-29
Abstract: A composition including, based on a total weight of the composition: 30 to 60 wt% of polycarbonate; 20 to 40 wt% of polybutylene terephthalate; 5 to 40 wt% of carbon fiber; 1 to 10 wt% of an ethylene acrylic ester terpolymer; and less than 5 wt% of glass fiber.
Patent EP-3775232-A1 (EP)
Title: Chemically-defined baculovirus expression system and cell culture medium
Inventor: YOVCHEVA MAYA
IPC: C12N5/00
Filed: 2019-04-11
Abstract: The present disclosure is related generally to systems and methods for high level expression of recombinant proteins from baculovirus in insect cells. In particular, the methods and systems described herein allow for high levels of baculovirus production in insect cells and/or high levels of protein production in insect cells using a chemically-defined, yeast lysate-free insect cell medium. The disclosure also relates to compositions and kits for culturing, transfecting, and/or producing recombinant protein in insect cells.
Patent EP-3781674-A1 (EP)
Title: Induction d'oligodendrocytes myélinisants dans des sphéroïdes corticaux humains
Inventor: TESAR PAUL
IPC: C12N5/079
Filed: 2019-04-16
Abstract: L'invention concerne une méthode de génération de sphéroïdes oligocorticaux à partir de cellules souches pluripotentes (humaines). Les sphéroïdes corticaux ainsi générés produisent des oligodendrocytes mûrs qui peuvent, par exemple, myéliniser des axones, et modéliser une maladie de la myéline et des effets de médicament.
Patent EP-3791394-A1 (EP)
Inventor: SCHMAUKE MATHIAS
IPC: G11C7/10
Filed: 2019-05-02
Abstract: Die vorliegende Erfindung betrifft einen statischen Direktzugriffsspeicher-Block (20) insbesondere für einen Empfangssensor, umfassend ein Speicherzellenfeld (21), einen Zeilenadressen-Dekodierer (22), einen Spaltendaten-Multiplexer (23), ein Lese- und Schreibmodul (24) umfassend einen Leseverstärker und einen Schreib-Treiber, eine Steuerlogik (25), einen Dateneingang (26) und einen Datenausgang (27). Der statische Direktzugriffsspeicher-Block (20) weist eine interne Speichertaktung auf. Erfindungsgemäß ist in den statischen Direktzugriffsspeicher-Block (20) mindestens ein Addierer (28) zum Addieren von durch den Dateneingang (26) eingegangenen Eingangsdaten integriert, wobei der mindestens eine Addierer (28) zwischen dem Dateneingang (26) und dem Lese- und Schreibmodul (24) angeordnet ist. Dadurch lassen sich die Lese- und Schreibvorgänge optimieren und so der Stromverbrauch senken. Die Erfindung betrifft außerdem einen Empfangssensor, insbesondere für ein Radar-oder Lidar-System, umfassend eine anwendungsspezifische integrierte Schaltung. Die anwendungsspezifische integrierte Schaltung umfasst mindestens einen erfindungsgemäßen statischen Direktzugriffsspeicher-Block (20).
Patent EP-3765937-A1 (EP)
Inventor: GU KAIWEN
IPC: G05D1/02
Filed: 2019-04-12
Abstract: Des aspects de la présente invention consistent à identifier et à répondre à des situations problématiques d'une flotte de véhicules aériens. Ceci peut consister à recevoir au niveau d'un ou plusieurs processeurs d'un ou plusieurs dispositifs informatiques de serveur une rétroaction de capteur provenant d'un AV de la flotte. Une situation problématique peut être identifiée à l'aide de la rétroaction de capteur. Une réponse d'atténuation pour la situation problématique liée à une mission attribuée au véhicule aérien peut être déterminée. La réponse d'atténuation peut être envoyée à l'AV afin d'amener le véhicule aérien à manœuvrer en fonction de la réponse d'atténuation et de répondre ainsi automatiquement à la situation problématique.
Patent EP-3804461-A1 (EP)
Inventor: MIRONOV OLEG
IPC: A24F40/465
Filed: 2019-05-24
Abstract: The present invention relates to a susceptor assembly for inductively heating an aerosol-forming substrate. The susceptor assembly comprises a multi-layer susceptor tube defining a cavity for receiving an induction coil inside the susceptor tube. The multi-layer susceptor tube comprises an inner tubular layer and an outer tubular layer surrounding the inner tubular layer. The inner tubular layer includes, preferably consists of a first electrically conductive material, whereas the outer tubular layer includes, preferably consists of a second electrically conductive material. An electrical resistivity of the first electrically conductive material is larger than an electrical resistivity of the second electrically conductive material. The invention further relates to an inductive heating assembly, an aerosol-generating article and an aerosol-generating system comprising such a susceptor assembly.
Patent EP-3793431-A1 (EP)
Inventor: TARNICERIU ADRIAN
IPC: A61B5/024
Filed: 2019-05-13
Abstract: A method for estimating the quality of a signal comprising: receiving a periodic signal comprising a first wave and a second wave; estimating similarity between the first wave and the second wave; assigning a weight for the second wave based on the similarity between the first wave and the second wave; classifying the second wave as non-reliable when the weight fails to exceed a predefined threshold.
Patent EP-3801689-A1 (EP)
Inventor: KIILERICH EBBE
IPC: A61M5/315
Filed: 2019-06-05
Abstract: A power unit (15) for use in an autoinjector (10) for driving a plunger (500) distally along an axis in an expelling movement so as to expel a drug from a held drug container, the power unit (15) comprising: a) a plunger (500) comprising retaining geometries (515) and defining radially protruding click protrusions (525), b) a drive spring (550) arranged in a tensed state with a force biasing the plunger (500) distally, and c) a power base (400) coupled to the drive spring (550) and the plunger (500), the power base (400) comprising a base part grounding the drive spring (550), and retaining elements (410) releasably engaging retaining geometries (515) of the plunger (500), the power base (400) further defining a resilient click arm (410) configured to cooperate with the click protrusions (525) of the plunger (500), the click arm (410) being moved radially to provide a click noise for each click protrusion that passes the click arm during the expelling movement, wherein the click arm (410) comprises a straining surface geometry (415d) arranged to cooperate, in a preparing step, with a tool (20) arranged distally relative to the click arm for moving the click arm (410) radially into a tensed state enabling the plunger (500) to be moved proximally. A method of assembling the power unit (15) is further disclosed.
Patent EP-3806739-A1 (EP)
Title: Temperature-insensitive membrane materials and analyte sensors containing the same
Inventor: BOMMAKANTI BALASUBRAHMANYA S
IPC: C08J5/18
Filed: 2019-06-11
Abstract: Membranes permeable to an analyte may overlay the active sensing region of a sensor to limit the analyte flux and improve the response linearity of the sensor. Temperature variation of the analyte permeability can be problematic in some instances. Polymeric membrane compositions having limited variation in analyte permeability as a function of temperature may comprise: a polymer backbone comprising one or more side chains that comprise a heterocycle; and an amine-free polyether arm appended, via an alkyl spacer or a hydroxy-functionalized alkyl spacer, to the heterocycle of at least a portion of the one or more side chains.
Patent EP-3826830-A1 (EP)
Inventor: KORSCH WOLFGANG
IPC: B30B15/30
Filed: 2019-07-12
Abstract: The invention relates to a device (10) for providing support lattices for use as inserts (12) in a pellet to a tableting machine (14) and to a method for producing a pellet which has an insert (12) in the form of a support lattice.
Patent EP-3802215-A1 (EP)
Inventor: LIPPI FABRIZIO
IPC: F03D13/40
Filed: 2019-05-29
Abstract: L'invention concerne un véhicule de marchandises (1), lequel véhicule a un châssis (6) avec au moins un pont de chargement (14) (15), une pluralité de chariots orientables (12) au-dessous du pont de chargement (14) (15) et un ensemble d'attachement et de support (18) pour la charge (2) à transporter, supporté par le châssis (6) ; l'ensemble d'attachement et de support (18) comportant une tête d'attachement (21) pour la charge à transporter, un système cinématique à barres multiples (28) pour coupler la tête de support (21) au châssis (6) et un actionneur (26) pour déplacer la tête de support (21) par rapport au châssis (6) avec un mouvement de roto-translation ; la tête de support (21) étant couplée au système cinématique à l'aide d'une charnière ayant un axe de charnière mobile (38) (39).
Patent EP-3738064-A1 (EP)
Title: System and method for implementing secure media exchange on a single board computer
Inventor: TUTIKA CHANDRA
IPC: G06F21/78
Filed: 2019-01-08
Abstract: An apparatus includes a single board computer (402) comprising a processing device (302). The apparatus also includes a touch screen display (404) coupled to the single board computer. The apparatus further includes at least one interface (310, 408) configured to be coupled to a storage device (304, 502). The processing device is configured to detect the storage device, perform a check-in process for the storage device, and generate a result of the check-in process for display on the touch screen display. To perform the check-in process, the processing device is configured to scan the storage device to identify any malware contained on the storage device, digitally sign one or more clean files on the storage device, and modify a file system of the storage device.
Patent EP-3802416-A1 (EP)
Inventor: MAZUBERT ALEX
IPC: C06B21/00
Filed: 2019-05-29
Abstract: The invention relates to a method for producing ammonium dinitramide (ADN) crystals, comprising: the addition of an ADN solution (S) in a polar solvent (S1) to a non-polar solvent (S2) that cannot dissolve ADN and is miscible with the polar solvent (S1), in a maximum quantity corresponding to a mass ratio of the polar solvent (S1)/(polar solvent (S1) + non-polar solvent (S2)) of 25%, in order to form an ephemeral emulsion of droplets of said ADN solution (S) in said non-polar solvent (S2), said droplets transforming into the desired ADN crystals by means of the inter-diffusion of the miscible polar and non-polar solvents (S1 and S2); the recovery of said crystals; and generally, the drying of the recovered crystals.
Patent EP-3743121-A1 (EP)
Inventor: ZURGIL NAOMI
IPC: A61L27/14
Filed: 2019-01-22
Abstract: L'invention concerne un dispositif de culture cellulaire et son procédé d'utilisation. Selon des modes de réalisation, le dispositif de culture cellulaire comprend une plaque comportant au moins un puits, un trou traversant étant formé au niveau d'une paroi de fond dudit puits, et une matrice d'hydrogel disposée dans le trou traversant. Le dispositif de culture cellulaire peut également comprendre une plaque optiquement transparente au fond du trou traversant.
Patent EP-3997234-A1 (EP)
Inventor: FABRITIUS DIRK
IPC: C07C49/643
Filed: 2019-07-08
Abstract: The present invention relates to a method for the stereo selective production of a trans-diol or a cis-diol or a hydroxyketone comprising the step(s) (i) conversion of a trans-diol or a cis-diol to a hydroxyketone and/or (ii) conversion of a hydroxyketoneto a cis-diol or a trans-diol, catalyzed by an enzyme, which is encoded by a nucleic acid sequence of SEQ ID NO: or wherein the enzyme comprises an amino acid sequence of SEQ ID NO: 2.The present invention also relates to the use of an enzyme encoded by a nucleic acid sequence of SEQ ID NO: 1 or wherein the enzyme comprises an amino acid sequence of SEQ ID NO: 2 for the conversion of a trans-diol to a cis-diol or for the conversion of a trans-diol or a cis-diol to a hydroxyketone and/or the conversion of a hydroxyketone to a trans-diol or a cis-diol.
Patent EP-3749943-A1 (EP)
Inventor: ENGSTRÖM CHRISTIAN
IPC: G01M15/00
Filed: 2019-01-31
Abstract: The present invention relates to a dynamometer test unit configured for use in a vehicle dynamometer system for dynamometer testing of a vehicle, the dynamometer test unit being configured to be connected to a wheel shaft of a vehicle, the dynamometer test unit comprising a power source having a stator and a rotor and being configured to, during testing, apply torque to a wheel shaft of the vehicle being tested, the power source being carried by a stator support, the stator being journaled in relation to the stator support, the dynamometer test unit further comprising means for measuring torque comprising an elastic strip, wherein the elastic strip connects the stator to the stator support, thereby restraining relative rotational movement between stator and stator support, and configured to transfer force between the stator and stator support, the elastic strip being firmly secured in a manner such that it is subjected to homogenous tensile prestress in a longitudinal direction of the elastic strip.
Patent EP-4000224-A1 (EP)
Title: Measuring round trip time in a mobile communication network
Inventor: SALKINTZIS APOSTOLIS
IPC: H04W88/06
Filed: 2019-07-18
Abstract: Apparatuses, methods, and systems are disclosed for measuring RTT. One apparatus (400) includes a processor (405) and a transceiver (425) that communicates (705) with a mobile core network via an interworking function. The processor transmits (710) a first request to establish a data connection between the apparatus and the mobile core network, wherein the first request includes a first indicator that the apparatus supports round trip time ("RTT") measurements, the RTT measurements calculated using messages transmitted via the data connection and using an encapsulation header. The processor receives (715) a first message from the interworking function and transmits (720) a second message to the interworking function, wherein the first message includes a first encapsulation header comprising an echo request indication wherein the second message includes a second encapsulation header comprising an echo response indication.
Patent EP-3843861-A1 (EP)
Inventor: MOLINARI ARTHUR PARKER
IPC: A63B41/08
Filed: 2019-07-26
Abstract: An inflatable sports ball having a bladder and a cover disposed about the bladder in provided. The cover may have an exterior surface that defines a plurality of plateau sections, a first plurality of indentations, and a second plurality of indentations that cooperate to define a topographical arrangement across the exterior surface. Each of the first plurality of indentations has a first indentation depth, a first indentation width, and a first maximum aspect ratio. The first maximum aspect ratio is defined as the ratio of the first indentation depth to the first indentation width. The second plurality of indentations has a second indentation depth, a second indentation width, and a second maximum aspect ratio. The second maximum aspect ratio is defined as the ratio of the second indentation depth to the second indentation width. The second maximum aspect ratio is greater than the first maximum aspect ratio.
Patent EP-3836844-A1 (EP)
Inventor: STIGALL JEREMY
IPC: A61B8/00
Filed: 2019-08-05
Abstract: Improved intraluminal imaging devices and methods of manufacturing the devices are provided. In one embodiment, an intraluminal imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion, an imaging assembly coupled to the distal portion of the flexible elongate member, the imaging assembly surrounding a lumen, and a tip member coupled to the imaging assembly, the tip member comprising a molded body including a guiding portion and an extended portion. The guiding portion extends distally of the imaging assembly, and the extended portion extends proximally of the guiding portion through the lumen within the imaging assembly. The tip member comprises a guidewire lumen extending through the guiding portion and the extended portion.
Patent EP-3755267-A1 (EP)
Inventor: GOTTARDI RICCARDO LUCA
IPC: A61K35/00
Filed: 2019-02-22
Abstract: Provided herein is a ligament ECM soluble fraction useful for the growth and regrowth of ligament tissue. Methods of preparation of the soluble fractions and use of the soluble fractions in growth or regrowth of ligament tissue also are provided.