Patent SG-11201903212Y-A (SG)
Title: Electronic driving circuit for driving electrodes of a microfluidic device for manipulation of particles, and corresponding analysis apparatus
Inventor: UCELLI MAURO
IPC: H03F3/217
Filed: 2017-10-18
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD 1101111 0 DOI HIM 011101 0 01111111 00111111111111111111111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\" WO 2018/073768 Al 26 April 2018 (26.04.2018) WIP0 I PCT (51) International Patent Classification: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, H03F 3/217 (2006.01) HO3F 1/32 (2006.01) DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (21) International Application Number: HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, PCT/IB2017/056482 KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (22) International Filing Date: OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, 18 October 2017 (18.10.2017) SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (25) Filing Language: Italian TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (26) Publication Language: English (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (30) Priority Data: GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, 102016000104760 18 October 2016 (18.10.2016) IT UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (71) Applicant: MENARINI SILICON BIOSYSTEMS EE, ES, FL FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, S.P.A. [IT/IT]; Via Giuseppe di Vittorio, 21 B/3, 40013 MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, Castel Maggiore (IT). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, (72) Inventors: UCELLI, Mauro; Via Verdi, 17, 44012 Bon- KM, ML, MR, NE, SN, TD, TG). deno (IT). TOMMASI, Andrea; Via Fermi, 70, 40055 Cas- tenaso (IT). MEDORO, Gianni; Via Gaspari, 5, 40033 Published: Casalecchio Di Reno (IT). — with international search report (Art. 21(3)) _ (74) Agent: NANNUCCI, Lorenzo et al.; c/o Studio Torta — S.p.A., Via Viotti, 9, 10121 Torino (IT). = (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, = AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, = (54) Title: ELECTRONIC DRIVING CIRCUIT FOR DRIVING ELECTRODES OF A MICROFLUIDIC DEVICE FOR MANIPU- LATION OF PARTICLES, AND CORRESPONDING ANALYSIS APPARATUS (57) : An electronic driving circuit (20) for a microfluidic device - (1), having a number of synchronized driving stages (22) to generate a re- POWER SUPPLY spective driving signal (Vi,V2,V3) for each electrode or group of electrodes 2, = i v„ , (4,6) of the microfluidic device, the driving signals having a desired ampli- _ = - FEEDBACK tude, frequency and -shift. Each driving has a -mode phase stage switching - MODULE = ' \"° '%; =111 II amplifier stage (22) to receive a clock signal (CK) and a target signal (V t ) and to generate, at an output (Out) thereof, an output signal (Vout) defining a — = ‘---25 GND = 22 = ) respective driving signal. The amplifier stage has: a switching module (23), coupled to a first internal node (N 1 ) and controlled by the clock signal for FEEDBACK v N selectively bringing the first internal node (N1) to a control signal (Y e ); a MOM. = — 29 N, N N, 111 filter module (25,26), coupled between the first internal node and the output, to provide the output signal; and a feedback module (29). = — 25 26 : 111 Il FEEDBACK MODULE GC .4 N2 MI esm NG PECONSTRI1CTION FILTER It ---- II/ 32 M 9c IN SVPRCHING-MODE 9D GENEPAIDR DC ET © POWER AMPUFIER ACTIVE P LOAD \ ... 1-1 Fig.3 0 C•1 O