Patent AU-2014201223-A1 (AU)
Title: Detection and monitoring of macrocyclic lactone resistance in nematodes
Inventor: PRICHARD ROGER
IPC: C12Q1/68
Filed: 2014-03-05
Abstract: The present disclosure concerns the determination of the resistance or the susceptibility of a nematode to a macrocyclic lactone anti-helminthic based on the characterization of the Dyf-7 gene (or Dyf-7 gene ortholog) or its corresponding gene products. The present disclosure also 5 provides tools and commercial packages for making such characterization. - 45 - CL CL CL aCIC 0-C M. 0. 0 L C .0 CLCCL M. a 1J % J J M J J1J | .I J1 %J J J J C Sli i : : l i i l : i I: .I l iii i ii : i I i i i i I Tj I W IE "m I [ I WI I I :T: 2 D2TT: O "rt 'T'! "01" I "'fT " C D "T"IIOM""I"I C "T W ""1"| 0 "'" "I 0 " m4IW LDI'QWNM.- CIM&IN r CDIMI NfuW CDININ M 4I"MIMNO CINl'M'.a O IDNIN CDw 6wX D A c A CD .O .6( C , LOA A .. L CD f, W rA - -'C I 1 zw I I I 1 I 1 ,O1= I I CD Cflfl CD A r CD rA. C- nn J C Jnn 13 J M A C r 01 1 A " m I A A!C . 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