baber/WOPTO huggingface dataset:
Patent CA-2884290-A1 (CA)
Inventor: SILACCI MELKKO MICHELA
IPC: A61P19/00
Filed: 2013-09-19
Abstract: The present invention relates to a polypeptide inhibiting the activity of glycosylated IL-17A, wherein the polypeptide comprises or consists of an amino acid sequence selected from the group consisting of: (a) GVTLFVALYDY(X1)(X2)(X3)(X4)(X5)(X6)DLSFHKGEKFQIL STHEYEDWWEARSLTTGETGYIPSNYVAPVDSIQ (SEQ ID NO: 1), wherein amino acid positions (X1) to (X6) may be any amino acid sequence; and (b) an amino acid sequence which is at least 85% identical to the amino acid sequence of (a), wherein the identity determination excludes amino acid positions (X1) to (X6) and provided that the amino acid sequence STHEYE (SEQ ID NO: 2) in amino acid positions 31 to 36 of SEQ ID NO: 1 is conserved. The invention also relates to fusion constructs, compositions and medical uses comprising said polypeptide.
Patent CA-2885665-A1 (CA)
Title: Method for the ex vivo expansion of hematopoietic stem and progenitor cells
Inventor: TURSKY MELINDA L
IPC: C12N5/078
Filed: 2012-09-21
Abstract: The present invention relates to hematopoietic cells, and more specifically to methods for long-term in vitro culturing and ex vivo expansion of hematopoietic cells. The present invention also provides compositions useful for culturing cells, such as media for culturing hematopoietic cells, specifically haematopoietic stem cells (HSC) and haematopoietic progenitor cells (HPC). The present invention further provides compositions including growth factor combinations and methods utilising altered growth and environmental conditions that are applicable in vitro culturing and to ex vivo expansion of HSC and/or HPC.
Patent CA-2888139-A1 (CA)
Inventor: DE BOE KRIS
IPC: B62D55/14
Filed: 2013-10-11
Abstract: A track assembly for traction of an off-road vehicle, the track assembly comprising a set of wheels and an endless track disposed around the set of wheels. The endless track comprises elastomeric material to flex around the set of wheels. The endless track comprises a plurality of drive/guide lugs projecting inwardly. The set of wheels comprises a drive wheel for imparting motion to the endless track. The set of wheels may comprise a first plurality of roller wheels for rolling on a first rolling path of the inner side and a second plurality of roller wheels for rolling on a second rolling path of the inner side such that the drive/guide lugs are located between the first rolling path and the second rolling path, as well as a third plurality of roller wheels for rolling on top of the drive/guide lugs.
Patent CA-2890420-A1 (CA)
Title: Double shaft drilling apparatus with hanger bearings
Inventor: BAUGHER DOUGLAS
IPC: E21B17/05
Filed: 2013-10-24
Abstract: A drilling apparatus includes a housing that defines a longitudinal axis. A power section of the apparatus includes rotor adapted to move with eccentric rotary motion with respect to the longitudinal axis in response to the passage of drilling fluids through the power section. A power transmission shaft has an upper end coupled to the rotor and movable with the eccentric motion of the rotor, and a lower end constrained to rotate in a concentric manner with respect to the longitudinal axis. A generally rigid torsion rod has upper and lower ends constrained to rotate in a concentric manner, and the upper end of the torsion rod is coupled to the lower end of the power transmission shaft.
Patent CA-2891280-A1 (CA)
Inventor: ZHAO R YONGXIN
IPC: C07F9/30
Filed: 2012-11-24
Abstract: Cell binding agent-drug conjugates comprising hydrophilic linkers, and methods of using such linkers and conjugates are provided.
Patent CA-2892484-A1 (CA)
Inventor: MAEDA SHUHEI
IPC: F16F1/36
Filed: 2014-12-18
Abstract: Provided is a rubber composition that is suitable for use in an air suspension for vehicles used in cold climates, said rubber composition exhibiting superior ozone resistance (as demonstrated by a dynamic ozone strain test) and cold resistance. Specifically provided is a cold-resistant rubber composition that includes a butadiene rubber, a chloroprene rubber, and a natural rubber or a rubber obtained by partially substituting a natural rubber with at least one specific rubber selected from the group consisting of styrene-butadiene rubbers and nitrile rubbers, wherein, with respect to a total of 100 parts by mass of the rubbers, the content of the butadiene rubber is 10-35 parts by mass, the content of the chloroprene rubber is 50-75 parts by mass, and the content of the natural rubber or the total content of the natural rubber and the specific rubber(s) is 10-35 parts by mass, and in cases when the specific rubber is present, the content of the specific rubber is preferably 10-60 mass% of the total content of the natural rubber and the specific rubber. Also provided is an air suspension for railway vehicles which uses the cold-resistant resin composition.
Patent CA-2892867-A1 (CA)
Inventor: MEYER JAMES M
IPC: E21B43/34
Filed: 2015-05-22
Abstract: Rich natural gas is first compressed, then ambient air cooled and separated into lean natural gas, NGL and water. Hydrate formation during decompression of the lean gas is precluded by either heating the lean natural gas or mixing the lean natural gas with methanol or other additive before depressurization. Similarly, hydrate formation in the NGL is also precluded by either heating the NGL or mixing the NGL with methanol or other additive before depressurization. The NGL is conditioned for storage and transport in common propane tanks by a stabilizer or two-phase separator. The lean natural gas can be used for internal combustion, liquefied natural gas, compressed natural gas or liquid fuel processing.
Patent CA-2893098-A1 (CA)
Title: Valve tronquee de protheses de valvule cardiaque
Inventor: BRUCHMAN WILLIAM C
IPC: A61F2/24
Filed: 2013-12-16
Abstract: La présente invention, selon des modes de réalisation, concerne des prothèses de valvule comportant des valves de forme particulière améliorant la caractéristique de flexion sans avoir recours à une valvule de grande longueur. Selon un mode de réalisation de la présente invention, une prothèse de valvule comprend un châssis de valves, plusieurs valves qui sont couplées au châssis de valves, chaque valve comportant un bord libre et une base. La base de chaque valve est tronquée, base dans laquelle la valve, lorsqu'on l'observe en coupe transversale, révèle une ligne dans un plan alpha sur le châssis de valves.
Patent CA-2896933-A1 (CA)
Inventor: MCCORMICK DANIEL F
IPC: A61F2/42
Filed: 2014-03-28
Abstract: A method and device to correct hammertoes. The device is a bone implant that includes an elongated body having a first threaded portion with a first thread pitch and a second threaded portion with a second thread pitch. When the implant is implanted into a joint and rotated about its longitudinal axis when mated with a driver bit, a target joint may be compressed using the pitch differential between the first and second threads. The first and second threads may also be disposed at opposing angles, to help prevent pistoning of the compressed bones. The implant can have one or two driving heads, to accommodate the different methods of insertion. The method involves surgically opening the PIP  joint, driving a first portion of a bone implant in one direction into one of the proximal and middle phalanges, aligning the toe such that the second portion of the implant is aligned with the other of the proximal and middle phalanges, and driving the implant in the opposite direction, using a driver bit inserted through the tip of the toe and through an intramedullary canal in the distal and middle phalanges, such that the second portion is driven into the other of the proximal and middle phalanges.
Patent CA-2899232-A1 (CA)
Inventor: IWAMOTO MITSUHIRO
IPC: A61P9/10
Filed: 2014-01-23
Abstract: The present invention provides a modified atrial natriuretic peptide that exhibits prolonged duration time in blood and maintains cGMP elevating activity. The present invention provides a modified peptide in which at least one sugar substance is linked directly through a glycosidic bond or via a linker structure to at least one hANP peptide, or a pharmaceutically acceptable salt thereof, a medicament comprising the modified peptide or the salt thereof as an active ingredient, etc.
Patent CA-2902275-A1 (CA)
Inventor: BOGGS JOSEPH H
IPC: B65D77/06
Filed: 2014-01-29
Abstract: A cartridge is provided that comprises a housing. The housing is configured to maintain a pouch within the housing. The cartridge comprises a top and a bottom. The cartridge comprises at least one top mating member at the top of the cartridge and at least one bottom mating member at the bottom of the cartridge. The at least one top mating member is asymmetric with the at least one bottom mating member. Each mating member is configured to match with a corresponding mating member of a cartridge frame or rack.
Patent CA-2903773-A1 (CA)
Inventor: WILLINGHAM STEPHEN
IPC: C07K16/28
Filed: 2014-02-26
Abstract: Methods are provided for treating a subject with a therapeutic dose of anti-CD47 agent by administering a primer agent prior to administering a therapeutically effective dose of an anti-CD47 agent to the subject. Turnover of cells begins with the induction of an apoptotic program or other cellular changes that mark them for removal, and the subsequent recognition of markers by phagocytes, including macrophages, dendritic cells, and the like. This process requires a specific and selective removal of unwanted cells.
Patent CA-2904586-A1 (CA)
Inventor: ZAGHOUANI HABIB
IPC: C12N5/16
Filed: 2014-03-10
Abstract: The disclosure relates generally to methods and compositions of treating or preventing diabetes mellitus by administering to a subject a composition comprising an amount of stem and/or progenitor cells and at least one antigen-specific therapy.
Patent CA-2909567-A1 (CA)
Title: Adjusting mobile device state based on user intentions and/or identity
Inventor: SCHILLINGS BENOIT M
IPC: H04W88/02
Filed: 2013-07-15
Abstract: In one embodiment, when a computing system is in a first state, a first set of inputs from one or more first sensors is detected. A first sensor value array is generated, and the first value array is fed as input to a first function generated by a first neural network. One or more first output values are calculated based on the first function, and a determination is made based on these first output values if a first action has occurred. If a first action has occurred, a second sensor value array is generated from a second set of inputs from one or more second sensors. The second sensor value array is fed as input to a second function generated by a second neural network. One or more second output values are calculated based on the second function, and the first state is exited based on these second output values.
Patent CA-2909995-A1 (CA)
Inventor: HERSLOF BENGT
IPC: A61K47/10
Filed: 2014-05-02
Abstract: The present invention provides topical pharmaceutical or cosmetic compositions comprising a pharmaceutical or cosmetic carrier comprising at least 3% by weight of phospholipid; at least 20 % by weight of C2-C4 alcohol;at least 0.05 % by weight keratolytic agent; and optionally,comprising up to 2 % by weight of water;and pharmacologically or cosmetically active agent dissolved in said carrier. The compositions are sprayable. Also disclosed is a method of preparing the composition and use thereof, as well as the pharmaceutical or cosmetic carriers as such.
Patent CA-2910321-A1 (CA)
Inventor: WEST ROBERT E
IPC: A61M5/19
Filed: 2014-04-24
Abstract: La présente invention concerne un dispositif d'injection doté de deux chambres à médicament et un ensemble aiguille de stylo de mélange, grâce auquel des posologies prédéterminées de deux médicaments peuvent être placées dans un réservoir mélangeur dans l'ensemble aiguille de stylo et administrés simultanément avec le dispositif d'injection.
Patent CA-2910992-A1 (CA)
Title: Elevator door with a door contact switch
Inventor: MULLER RUDOLF J
IPC: F16P3/14
Filed: 2014-05-27
Abstract: The invention relates to a switching device (4) for an elevator door (2) for providing a door contact signal (S). The switching device (4) comprises a magnet (20), a plurality of proximity sensors (22a, 22b; 22c, 22d), and a detection area (DR), which is adjoined by the proximity sensors (22a, 22b; 22c, 22d) and in which the magnet (20) can be moved. A sensor signal (24a, 24b, 24c, 24d) can be generated by each of the proximity sensors (22a, 22b; 22c, 22d) in at least one position of the magnet (20) in the detection area (DR), wherein the sensor signals (24a, 24b, 24c, 24d) are dependent on the distance from the magnet (20) to the proximity sensors (22a, 22b; 22c, 22d). The invention also relates to a method for providing a door contact signal (S) by means of said switching device (4).
Patent CA-2912315-A1 (CA)
Inventor: BIEL MARKUS CHRISTIAN
IPC: C11D7/32
Filed: 2014-05-13
Abstract: Aqueous solution comprising (A) in the range of from 30 to 60% by weight of a complexing agent, selected from the alkali metal salts of methylglycine diacetic acid and the alkali metal salts of glutamic acid diacetic acid, (B) in the range of from 700 ppm to 7% by weight of a polymer being selected from polyamines, the N atoms being partially or fully substituted with CH2COOH groups, partially or fully neutralized with alkali metal cations, ppm and percentages referring to the total respective aqueous solution
Patent CA-2912507-A1 (CA)
Title: Composes d'ammonium quaternaire et compositions d'inhibiteur d'hydrate gazeux
Inventor: GRAINGER NEIL
IPC: C09K8/035
Filed: 2014-07-31
Abstract: L'invention concerne des composés d'ammonium quaternaire et des compositions comprenant ces composés. Les compositions sont précieuses en tant qu'inhibiteurs d'hydrate gazeux dans les industries d'exploration, de récupération et de traitement de pétrole et de gaz. Ces composés et compositions présentent une biodégradabilité améliorée et une toxicité réduite par rapport à des matières de référence. Les composés d'ammonium quaternaire de la présente invention sont représentés par la formule (I), dans laquelle R représente un alkyle en C1-4, un aryle en C6-10 ou un C1-4alkyle-C6-10aryle ; R1 représente un hydrogène ou un groupe représenté par la formule -C(=0)X ; et R2 représente un hydrogène ou un groupe représenté par la formule -C(=0)Y, à condition que R1 et R2 ne représentent pas tous deux un hydrogène ; X et Y représentent chacun indépendamment un hydrogène, un alkyle en C1-6 ou un groupe alcényle en C1-6, et Z représente un alkyle en C4-24 ou un groupe alcényle en C4-24 ; chaque D représente indépendamment un alcylène en C1-4 ; et A- représente un anion.
Patent CA-2915156-A1 (CA)
Title: Attachable receptacle
Inventor: BEIJ JACQUES
IPC: A47L1/06
Filed: 2014-05-30
Abstract: The invention relates to a collector container (1) for a cleaning device (2), wherein the cleaning device (2) has an elongate main part (2a) with a centrally positioned handle element (2b) or a fastening element (2p) for a stem or handle, and a wiping blade (2c) is fastened to the main part (2a), and wherein the collector container (1) can be fastened or more particularly clipped to the main part (2a) of the cleaning device (2).
Patent CA-2917301-A1 (CA)
Title: Heat activated shrink films
Inventor: PHAM HOANG T
IPC: F16L47/22
Filed: 2014-07-02
Abstract: Shrinkable film layers having a blend of (i) one or more polymers with a high glass transition temperature, and (ii) one or more polymers with a low glass transition temperature are disclosed. Methods for preparing such film layers are also disclosed.
Patent CA-2919017-A1 (CA)
Title: Intermodal container and method
Inventor: YOUNG STEWART W
IPC: B65D88/02
Filed: 2016-01-22
Abstract: There is described an intermodal container that has been modified to include an alcove structure in one of the side walls. The alcove is sized for insertion and periodic removal of a portable toilet.
Patent CA-2921065-A1 (CA)
Inventor: JASMIN SIMON
IPC: H02J3/28
Filed: 2014-08-06
Abstract: A power control device for controlling electrical power transferred between an AC power grid and a load or between the AC power grid and an auxiliary power source. For example, the power control device may be configured to monitor an electrical characteristic of electrical energy supplied by the AC power grid to the load and to adjust a consumption of the electrical energy by the load when the electrical characteristic indicates that the AC power grid is no longer in a state of balance. As another example, the power control device may be configured to control an electrical energy injection process during which an injection of electrical energy from the auxiliary power source into the AC power grid is increased in relation to a detected rate of deviation of the AC power grid frequency. As yet another example, the power control device may be configured to adjust an injection of electrical energy into the AC power grid according to a magnitude of kinetic energy bleed from the AC power grid that is derived during an occurrence of a power generation deficit within the AC power grid.
Patent CA-2923674-A1 (CA)
Inventor: O'FLYNN PADRAIG M
IPC: A61M25/00
Filed: 2014-12-03
Abstract: A catheter assembly (10) includes a catheter (12) at least partially positioned within a sleeve (14). The catheter has a coating, which produces a low-friction surface on the catheter when treated with an activating fluid. A protective tip (16) is connected to the proximal end (18) of the sleeve (14) and has proximal (28) and distal (30) internal seals, with the proximal seal (28) at the proximal end (24) of the tip (16) or between proximal (24) and distal (22) ends of the protective tip (16). A cap (32) of the assembly has a projection (34), which is removably received within the protective tip (16) for sealing engagement with the proximal (28) and distal (30) seals to define a fluid reservoir (38) within the protective tip (16). An activating fluid is contained within the fluid reservoir (38). The projection (34) may be partially hollow to receive a portion of the catheter (12). The sleeve (14) may be relatively narrow or at least have a narrowed portion for better distribution of activating fluid to the surface of the catheter.
Patent CA-2924162-A1 (CA)
Inventor: VACHON LEANDRE
IPC: A63C19/00
Filed: 2014-10-20
Abstract: The tile (100) includes a monolithic support grid structure (102) having a rectangular configuration with four peripheral edges (104, 106, 108, 110). The support grid structure (102) includes a lattice framework of elongated rib members (120, 122) crisscrossing at right angle on the underside of the support grid structure (102) and defining a network of cells (124). The support grid structure (102) also includes a plurality of support members (130), each downwardly projecting from a corresponding intersection (128) between the crisscrossing elongated rib members (120, 122) and having a ground-engaging distal end with a tip (132) that is coincident with a common bottom plane. The tile (100) includes a plurality of tile edge connectors (140) that are positioned on the underside and made integral with the support grid structure (102).
Patent CA-2928334-A1 (CA)
Title: Corrosion-resistant refractory binder compositions and oil well completion and production operations
Inventor: AGAPIOU KYRIS
IPC: C09K8/03
Filed: 2013-12-18
Abstract: Corrosion-resistant refractory binder compositions may include high alumina cement, high-alumina refractory aluminosilicate material, and phosphorous material. Examples of high- alumina refractory aluminosilicate material include crushed firebrick, firebrick grog, refractory mortar, fire clay, mullite, fused mullite, and combinations thereof. The binder composition may be mixed with sufficient amount of fluid such as water to form a slurry and introduced into a wellbore penetrating a subterranean formation, where it may be allowed to set at a point downhole. Such compositions, once set, may exhibit enhanced corrosion and heat resistance. Such compositions, once set, may additionally be cured. Curing may take place at higher temperatures and/or pressures, and may furthermore increase temperature resistance and/or strength of the set binder composition. In addition, the inclusion of high-alumina refractory aluminosilicate material may provide for enhanced consistency in such binder compositions formulated from different batches of high-alumina refractory aluminosilicate material.
Patent CA-2929665-A1 (CA)
Title: Element de guidage, ensemble de guidage, systeme et procede pour separer les visceres evisceres de volailles abattues
Inventor: THRANE UFFE
IPC: A22C21/06
Filed: 2014-11-14
Abstract: Cette invention concerne un élément de guidage (4) servant à séparer les viscères éviscérés de volailles abattues comprenant une surface de support de séparation (41, 42) comportant une ouverture allongée (43) destinée à recevoir les viscères (1) de façon qu'au moins les intestins (15) et la vésicule biliaire (18) restent en suspens sous ledit élément de guidage (4) et que le foie (16) et le gésier (17) se retrouvent au-dessus dudit élément de guidage. L'ouverture allongée (43) s'étend à partir d'un bord avant de la surface de support de séparation et une partie distale de l'ouverture est décalée par rapport à une section proximale dans un sens sensiblement parallèle au bord avant. Un élément de préhension (3) peut être placé sous ledit élément de guidage pour se saisir d'une partie des intestins (15). Dans un procédé selon l'invention, l'élément de guidage (4) est amené au contact des viscères de façon que les intestins et/ou la vésicule bilaire s'engagent dans l'ouverture allongée.
Patent CA-2930683-A1 (CA)
Inventor: JOERN PAUL
IPC: B32B37/00
Filed: 2016-05-19
Abstract: A stiffened fuselage component (10) made of a fiber reinforced composite material, in particular for use in an aircraft, comprises a skin element (12) and a plurality of elongated stiffening elements (18) forming a stiffening element pattern comprising a plurality of node points (20) and being attached to an inner surface (16) of the skin element (12), wherein at least some of the node points (20) are defined by an intersection of at least two stiffening elements (18) at an acute angle or an obtuse angle, and wherein at least some of the elongated stiffening elements (18) are shaped so as to define an internal cavity (22) delimited by an inner surface (24) of the stiffening elements (18) and covered by the skin element (12).
Patent CA-2931321-A1 (CA)
Title: Procede d'agglomeration sous forme de boulette de minerais finement divises
Inventor: SAATCI ALPAYDIN
IPC: C22B23/00
Filed: 2014-12-16
Abstract: La présente invention concerne l'agglomération sous forme de boulette de particules de minerai finement divisé comprenant les étapes suivantes: a) mélanger des particules de minerai avec de l'eau à laquelle a été ajoutée des substances tensioactives, b) ajouter un liant et au moins un agrégat servant à la préparation d'un mélange d'agglomération sous forme de boulette, c) fournir le mélange d'agglomération sous forme de boulette à un dispositif d'agglomération sous forme de boulette, et d) traiter le mélange de d'agglomération sous forme de boulette dans le dispositif d'agglomération sous forme de boulette afin d'obtenir des boulettes par addition d'eau à laquelle a été ajoutée des substances tensioactives.
Patent CA-2931559-A1 (CA)
Inventor: VERHOEVEN WILLY J H
IPC: A61K9/00
Filed: 2014-12-08
Abstract: Described herein is an intra-vaginal drug delivery system comprising (i) a core comprising a first thermoplastic polymer and a first therapeutic agent, wherein the first therapeutic agent is dissolved in the first thermoplastic polymer, and (ii)a skin surrounding the core comprising a second thermoplastic polymer, wherein the first therapeutic agent is less permeable in the second thermoplastic polymer than the first thermoplastic polymer, and a second therapeutic agent in solid form, wherein the second therapeutic agent is loaded in a portion of the skin.