baber/WOPTO huggingface dataset:
Patent PT-711305-E (PT)
Inventor: LEHRER ROBERT I
IPC: A01N63/50
Filed: 1994-07-20
Abstract: Peptide-based compounds containing four invariant cysteine residues which have been optionally oxidized to contain two intramolecular disulfide bonds, or modified forms where the cysteines are replaced are useful as preservatives and in preventing, treating, or ameliorating viral or microbial infection in animals and plants, and in inactivating endotoxin. These compounds, in one embodiment, are of the formula:A1-A2-A3-A4-A5-C-A7-C-A9-A10-A11-A12-C-A14-C-A16-(A17-A18)(1)and the N-terminal acylated and/or C-terminal amidated or esterified forms thereof, either in optionally -SH stabilized linear or in cystine-bridged form wherein A1 and A9 are basic amino acids; A2, A3 and A10 are small amino acids; A5, A7, A12, A14 and A16 are hydrophobic amino acids; and A4 is a basic or a small amino acid; A11 is a hydrophobic amino acid; A17 is not present or, if present, is a small amino acid; A18 is not present or, if present, is a basic amino acid, and modified form of formula (1) wherein each of 1-4 cysteines is independently replaced by a hydrophobic amino acid or a small amino acid.
Patent PT-768429-E (PT)
Inventor: MULLER HARALD
IPC: E01B26/00
Filed: 1996-10-09
Abstract: The safety barrier has a holding bar (1) with a projecting support (5) for a barrier, in order to protect a rail section (3) on a track, and has equipment (4) to form a detachable fastening with the rail. The bar has a retaining region (6), which grips around the profile of the rail against the force of an elastic spring element (7). The element is in the form of a helical compression spring (17), which is supported against an abutment which limits the maximum possible travel of the retaining region in the direction of a retaining stop (9). The abutment is attached to a profile component (15) on the fixed retaining stop at a place which at a distance from the stop part (13).
Patent PT-848009-E (PT)
Inventor: RIJST MARCEL VAN DER
IPC: C07H15/252
Filed: 1996-12-16
Abstract: This invention relates to a novel method for the chemical preparation of epirubicin or acid addition salts thereof, in particular the HCl salt, from daunorubicin. This process avoids the disadvantages of the prior art. First daunorubicin is methanolized to obtain daunomycinone and daunosamine methyl ether in very high yields. Daunomycinone is converted to 14-acetoxy daunomycinone by bromination and acetoxylation, while daunosamine methyl ether is converted into an N-protected 4'-epi daunosamine. The choice of the protecting group of the amino group of the daunosamine methyl ether is important because it has to be removed after coupling the sugar with the aglycone without causing side reactions of the aglycone. Two protecting groups were selected: the trifluoroacetyl group and the allyloxycarbonyl group. After coupling the 14-acetoxy daunomycinone with the N-protected 4'-epi daunosamine, the obtained compound was converted to epirubicin; for the latter conversion two routes were developed, depending on the amino-protecting group.
Patent PT-737685-E (PT)
Inventor: RENARD PIERRE
IPC: C07F7/02
Filed: 1996-04-11
Abstract: Furo-, thieno- or pyrrolo-pyridine derivs. of formula (I), and their isomers and salts are new. X = O, S or NR7; R1-R4 = H, halo, OH, Ra or ORa; Ra = alkyl, haloalkyl, trialkylsilyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, or opt. substd. aryl or arylalkyl; either R5 = -A-B-Y; and R7 = H, alkyl, or opt. substd. aryl or arylalkyl; or R7 = -A-B-Y and R5 = as for R1-R4; A = 1-6C alkylene opt. substd. by one or more alkyl gps.; B = -NR6-C(=Z)- (B1), -NR6-C(=Z)-NH- (B2) or -C(=Z)-NR6- (B3); Y = H or Y1, but not H when B = B3; Y1 = alkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl or cycloalkylalkyl; Z = O or S; R6 = H, alkyl, cycloalkyl, cycloalkylalkyl, aryl or arylalkyl; provided that: (a) (I) is not N-(2-(1H-pyrrolo Ä3,2-cÜ pyridin-3-yl) ethyl)- acetamide; and (b) R7 is not phenyl when the N atom of the pyridine ring is in position 7 of the heterocycle, R1 = alkyl in position 4 of the heterocycle, and R2-R4 = H; alkyl, alkoxy = 1-6C; alkenyl, alkynyl = 2-6C; cycloalkyl = 3-8C; aryl = phenyl, naphthyl or pyridyl; substd. aryl or arylalkyl has one or more substits. selected from halogen, alkyl, alkoxy, OH and haloalkyl.
Patent PT-814861-E (PT)
Inventor: CHAWLA BRINDRA PAUL SINGH
IPC: A61M15/00
Filed: 1996-03-14
Abstract: PCT No. PCT/EP96/01092 Sec. 371 Date Sep. 10, 1997 Sec. 102(e) Date Sep. 10, 1997 PCT Filed Mar. 14, 1996 PCT Pub. No. WO96/28205 PCT Pub. Date Sep. 19, 1996The invention relates to an ultrasonic atomizer device (2) for a fluid (60), in particular a bronchospasmolytic agent, in which a propelling element (10) operable by an electronic circuit (6) to deliver the fluid to an atomization surface (28) that is also supplied with ultrasound waves from the electronic circuit (6) is provided in a housing (4), the propelling element (10) having a coupling member (32) which is meshing with a further coupling member (34) of a replaceable dosating unit (14) for transferring propelling power to the dosating unit (14) to effect a linear movement (68) of a piston (66) arranged in an ampoule (28) within the dosating unit (14). The invention also relates to a system comprising a device (2) as described and a dosating unit (14) inserted into that device (2).
Patent PT-821718-E (PT)
Inventor: PODOLA TORE
IPC: C09K3/10
Filed: 1996-04-09
Abstract: PCT No. PCT/EP96/01512 Sec. 371 Date Oct. 15, 1997 Sec. 102(e) Date Oct. 15, 1997 PCT Filed Apr. 9, 1996 PCT Pub. No. WO96/33249 PCT Pub. Date Oct. 24, 1996Described is a moisture-curing sealing and bonding compound made from completely synthetic polymers, the compound containing, to improve its non-sag properties, a triglyceride, either as the sole non-sag agent or in addition to prior art agents. The triglyceride should have a melting point over 40 DEG  C., preferably over 50 DEG  C., and be derived from saturated fatty acids with 8 to 26 C-atoms. Even without using thixotropic agents, compounds can be obtained which do not sag at temperatures over 40 DEG  C. Such joint sealants can be used to fill joints more than 35 mm wide without sagging.
Patent PT-863729-E (PT)
Inventor: CANELAS ALBERTO HERMINIO MANIQ
IPC: A61K31/00
Filed: 1996-09-26
Abstract: A simple and implantable sustained release drug delivery device with an inner core containing an effective amount of a low solubility agent covered by a non-bioerodible polymer coating layer that is permeable to the low solubility agent is disclosed. A method for treating a mammal to obtain a desired local or systemic physiological or pharmacological effect by surgically implanting such a sustained release drug delivery device into a mammal in need of treatment is also disclosed.
Patent PT-850926-E (PT)
Inventor: MATSUMURA YASUSHI
IPC: A61P27/02
Filed: 1997-12-22
Abstract: A fluorine-containing prostaglandin derivative of the formula (1) or a salt thereof, and a medicine containing it, particularly, as a preventive or therapeutic medicine for an eye disease: <CHEM> wherein A is a vinylene group or the like, R<1> is an aryloxyalkyl group or the like, R<2> and R<3> are hydrogen atoms or the like, and Z is OR<4>, therein OR<4> is a hydrogen atom or an alkyl group or the like.
Patent PT-819009-E (PT)
Inventor: EMPERAIRE JEAN-CLAUDE
IPC: A61P15/00
Filed: 1997-01-31
Abstract: The invention relates to medicaments for initiating ovulation comprising LH in an administrable form which ensures an increase in LH plasma levels for a period of some 40 to 60 hours.
Patent PT-931148-E (PT)
Inventor: DEISHER THERESA A
IPC: C12N15/18
Filed: 1997-10-16
Abstract: There is provided an isolated polynucleotide molecule encoding a fibroblast growth factor (FGF) homolog polypeptide selected from the group consisting of: a) a polynucleotide molecule comprising a nucleotide sequence as shown in SEQ ID. NO:1 from nucleotide 82 to nucleotide 621; b) allelic variants of (a); c) a polynucleotide molecule that encode a polypeptide that is at least 60% identical to the amino acid sequence of SEQ ID. NO:2 from amino acid residue 28 (Glu) to amino acid residue 207 (Ala); and d) a polynucleotide molecule comprising a nucleotide sequence as shown in SEQ ID. NO:6 from nucleotide 82 to nucleotide 621.
Patent PT-948661-E (PT)
Inventor: BELLIDO-GONZALEZ VICTOR
IPC: C23C14/06
Filed: 1997-12-10
Abstract: Disclosed is a metal sulphide coating composition of the formula MXSiVRYSZFW where M is one or more metals selected from: Mo, Ti, W, Nb, Ta, Zr, and Hf; Si is silicon; R is one or more elements selected from: C, B, Al, V, Cr, Fe, Co, Ni, Sm, Au, Cu, Zn, Sn, Pb, N, H, and O; S is sulphur; F is fluorine; X is 0.2 to 1.5; V is 0.02 to 3; Y is 0 to 4; Z is 0.2 to 6; and W is 0.01 to 6, and in which X, Y, Z, V, and W are given in amounts by atomic ratio. The compositions show good non-stick properties, low hydrophilia, and high stability.
Patent PT-994697-E (PT)
Inventor: SINGH NAGI ARWINDER
IPC: A61P31/00
Filed: 1998-06-11
Abstract: This invention provides rapamycin solid dosage unit which comprises a core and a sugar overcoat, said sugar overcoat comprising rapamycin, one or more sugars, and one or more binders.
Patent PT-1025179-E (PT)
Title: Use of an aqueous polyacrylic preparation for labelling
Inventor: ONUSSEIT HERMANN
IPC: C09J133/06
Filed: 1998-10-17
Abstract: Aqueous adhesive preparations, especially for labeling bottles, should have a high adhesion value and be odorless when removed again. To this end, aqueous preparations are utilized which contain 1 to 70 wt. % of a copolymer from acid group carrying monomers and hydrophobic monomers. If desired, the aqueous preparations can contain one or more admixture components for improving the wet adhesive strength and/or for adjusting the open time. If desired, said preparations can additionally contain preservatives, antifoaming agents, dyes and/or other common auxiliary agents. The inventive preparations can be utilized as labeling adhesives for attaching water permeable hydrophilic substrates to hard surfaces.
Patent PT-997393-E (PT)
Inventor: MARBLER CLAUDE
IPC: B65D77/28
Filed: 1999-07-02
Abstract: The bag(10) has a first section(32) to hold a liquid substance and a second section(34) separated fluidtight from the first section to accommodate a drinking straw section(42). The straw(38,42) leads from the first section into the second section, is connected fluidtight to the bag in the transition region, and has a valve element for opening and closing of the flow passage(37). The straw may have a joint movable between an open and closed position by hinging or twisting the straw section protruding into the second section.
Patent PT-1114220-E (PT)
Inventor: DYLLICK-BRENZINGER RAINER
IPC: D21H21/12
Filed: 1999-07-20
Abstract: Antifoams and/or deaerators are based on oil-in-water emulsions which contain, in the hydrophobic oil phase, at least one compound effective as an antifoam and/or deaerator and, if required, further components, the oil-in-water emulsions containing from 0.01 to 3% by weight of a water-soluble, amphiphilic copolymer having acid groups or of a water-soluble salt thereof as a stabilizer.
Patent PT-1120111-E (PT)
Title: Method for stabilising an active substance in a tablet
Inventor: WATANABE YASUSHI
IPC: A61K9/28
Filed: 1999-10-05
Abstract: A tablet including active substance affected by lubricant, wherein the tablet is comprised of compressed mixture of active substance and adjuvant except for lubricant, and lubricant exists only on the surface of the tablet but is not included in the tablet. Such a tablet production method comprising the steps of producing mixture of active substance affected by lubricant and adjuvant, mixing lubricant powder with positive pulsating vibration air for dispersion, spraying the lubricant powder dispersed by the positive vibration air on a lower surface of an upper punch, an upper surface of a lower punch and an inner circumferential wall of a die, and tabletting the mixture by means of the upper and lower punches and the die.
Patent SG-89890-G (SG)
Title: Steam iron
IPC: D06F75/26
Filed: 1990-10-31
Abstract: A steam iron comprises at least two heating elements (4, 6), of which at least one element (6) serves for heating a steam boiler (5) for steam production and at least one other element (4) serves for heating the sole plate. In order to obtain a substantially higher heat transfer between the iron and the fabric the iron is constructed in such a way that the heating element(s) for steam production deliver(s) a higher power than the element(s) for sole-plate heating. Suitably, the total power of the heating elements is at least 1400 W. The transfer of heat from the iron to the fabric is effected by steam condensation within the fabric, which proceeds considerably faster than by thermal conduction.
Patent SG-133392-G (SG)
Title: A mold clamping device
IPC: B29C45/67
Filed: 1992-12-29
Abstract: Clamping cylinder 22 slidably receives a clamping ram 26 whose front end is fixed on a movable board 20 of (e.g.) an injection molding machine (21,23-25) and which has a chamber opening in its rear face. The interior of the clamping cylinder 22 is divided into a rear chamber W and a front chamber X by the large-diameter piston section of the clamping ram 26. From the inner rear wall of the clamping cylinder 22 there projects, a mold opening piston having a front end which slidably fits in the chamber in the clamping ram 26. The opening piston has a large-diameter piston section which divides the chamber into a rear chamber Y and a front chamber Z which communicates with the atmosphere. A hydraulic controlling device 31-37 controls the connection of the chambers X,Y and Z to each other and to an oil pressure source 40. Thus it connects the chambers X and Y to the chamber W for high-speed mold closure. It connects the chamber W to the oil pressure source 40 and relieves the pressure in the chambers X and Y for tight clamping; and it connects the chamber Y to the oil pressure source and connects the chamber W to both the chamber X and the relief means 32 for opening the mold. Preferably, the effective pressure receiving area of the chamber Y is to be equal to the cross-sectional area of the chamber section of the clamping ram 26.
Patent IE-34928-L (IE)
Title: Container closure
IPC: B65D43/06
Filed: 1971-02-03
Abstract: 1352253 Container closures DART INDUSTRIES Inc 19 April 1971 [3 Feb 1970 27 Aug 1970] 20829/71 Heading B8T A closure 10 has radial pleats 18 in its topwall 14 which taper inwardly and downwardly to a plane central region 16 from an upwardly and outwardly sloping wall 26 with an outside diameter greater than the diameter of the mouth of the container. To fit the closure it is placed on the container and downward pressure is applied to the region 16. The pleats 18 collapse upon themselves displacing the wall 26 inwardly and the closure is pushed on until a bead 32 has snapped under the undercut below the sloping wall 36. Air expelled from the container egresses through gaps between ribs 25 on the inside of walls 33, 37. When the downward pressure is released the closure tends to regain its original shape and wall 26 sealingly engages wall 36. An additional seal may be provided between the container wall and a ridge on the inside of wall 37. To remove the closure the lip 12 is prised upwardly. The wall 37 may be omitted.
[GB1352253A]
Patent IE-800129-L (IE)
Title: Coin acceptor or rejector
IPC: G07D/
Filed: 1980-01-23
Abstract: A coin acceptor apparatus has circuitry for energizing a first coil so as to induce a signal in a second coil while a coin to be tested is passed between the coils. Circuitry is further provided for cancelling the signal induced in the second coil when a genuine coin passes between the coils, so that the resultant signal is reduced below a predetermined level. Also, the apparatus accepts the coin when the resultant signal is below the predetermined level, and rejects it when the signal is above the predetermined level.
[US4257512A]
Patent IE-820150-L (IE)
Title: Metal oxide varistor
IPC: H01C17/28
Filed: 1982-01-25
Abstract: Solderable, largely based metal electrodes for metal oxide varistors are fabricated by screen printing an electrically conductive, air-fireable base metal composition on a varistor material substrate. A distributed fine noble metal array is screen printed over the screened base metal and the varistor heated in air at a temperature of between approximately 500 DEG C. and 800 DEG C. The varistor leads are easily solderable to the noble metal array.
[US4441094A]
Patent IE-40588-L (IE)
Title: 3,4-dihydro-2-pyridone derivatives
IPC: C07D211/90
Filed: 1975-02-07
Abstract: 3,6-Diamino-3,4-dihydro-2-pyridones of the formula ##SPC1## Wherein R.sub.1 is straight or branched chain alkyl or alkenyl or said alkyl or alkenyl interrupted by 1 or 2 oxygen atoms; R.sub.2 is straight or branched chain alkyl; alkenyl; alkynyl; cycloalkyl; cycloalkenyl; cycloalkynyl; aryl unsubstituted or substituted by 1 to 3 of the same or different substituents selected from the group consisting of alkyl, alkoxy, halogen, nitro, cyano, trifluoromethyl, carbalkoxy and SO.sub.n -alkyl wherein n is 0 to 2; naphthyl; quinolyl; isoquinolyl; pyridyl, pyrimidyl, thienyl; or furyl; and R.sub.3 is straight or branched chain alkyl; or aryl unsubstituted or substituted by alkyl, alkoxy, nitro, trifluoromethyl or halo; Are produced by reacting a 4-ylidene-1,3-oxazoline-5-one of the formula ##SPC2## Wherein R.sub.2 and R.sub.3 are as above defined, with an amidinoacetic acid ester of the formula ##EQU1## or a salt thereof, WHEREIN R.sub.1 is as above defined, In the presence of an inert inorganic solvent and either in the presence of or in the absence of a catalytic amount of an alkali alcohol at a temperature of from about 20.degree. C to about 200.degree. C.[US4001259A]
Patent IE-830369-L (IE)
Title: Carburettor
IPC: F02M17/10
Filed: 1983-02-22
Abstract: A carburettor for an internal combustion engine has an air passageway in which air flow is controlled by a poppet valve in which fuel is fed from a tapered needle controlled valve readily variable for different fuels including CNG, LPG, Methanol and petrol. A movable assembly comprises the poppet valve connected to a movable wall, the latter separating a first and second pressure chamber and a low pressure control valve is manually programmable to take up a position relative to the movable assembly preferably the movable wall to control pressure in the first pressure chamber against a balancing pressure in the second pressure chamber and a biasing means to control the position of the poppet valve and the fuel valve and hence the power of an internal combustion engine on which the carburettor is fixed in accordance with selected positions of a manual control.
[US4455979A]
Patent IE-860535-L (IE)
Title: Encapsulated antineoplastic agents
IPC: A61K9/08
Filed: 1986-02-27
Abstract: Anthracycline anti-neoplastic agents are formulated in phospholipid micellular particles. In a preferred embodiment, the particles are in the form of vesicles which comprise an anthracycline agent, preferably daunorubicin, distearyl phosphatidyl choline, distearyl phosphatidyl glycerol and cholesterol, preferably in a molar ratio of about 1:2:0:0 to about 1:4:20:20. The vesicles are suspended in a low ionic solution such as 5% dextrose at pH 7.4.
Patent IE-31911-L (IE)
Title: Diphenylpyridazones
IPC: C07D403/06
Filed: 1968-05-16
Abstract: 1,157,045. Diphenyl-pyridazones. SEPERIC. 10 May, 1968 [19 May, 1967], No. 23462/67. Heading C2C. Novel pyridazones of formula wherein Ar and Ar<SP>1</SP>, which may be the same or different, are phenyl groups, or phenyl groups mono- or poly-substituted with halogen atoms, alkyl, hydroxy, alkoxy, alkylamino or trifluoromethyl groups, X is hydrogen or a lower alkyl group, of 1-4 carbon atoms, n is an integer equal to one or more, the various X's, when n is greater than one, not being necessarily identical, and Y is a dialkylamino group, or a heterocycle, alkyl substituted or not, containing a nitrogen atom, said heterocycle optionally having a second hetero atom and being bound to group (CHX) n by its nitrogen atom or by one of its nuclear carbons, and the acid addition salts of said pyridazones; are prepared by condensing α,γ-diphenyl-γ-ketonic acids, prepared by known processes, or an ester of such acid, with hydrazines of general formula H 2 N-NH-R, wherein R is hydrogen or a -(CHX) n -Y group wherein X, Y and n have the same meaning as above, to give a 4,6-diphenyl-pyridazinone of formula in which Ar, Ar<SP>1</SP> and R are as given above, which is dehydrogenated to the corresponding pyridazones, and when R is hydrogen, introducing group (CHX) n -Y by condensation of the 2- unsubstituted diphenyl-pyridazone with a halide of formula Z-(CHX) n -Y where X, n and Y are as above and Z is halogen. Pharmaceutical compositions of the above compounds having psychotropic and analgesic activity are administered orally, parenterally, rectally or by injection.
[GB1157045A]
Patent IE-44655-L (IE)
Title: Extracting energy from movement of water
IPC: F03B13/20
Filed: 1977-03-21
Abstract: This invention relates to apparatus for converting into useful energy movements imparted thereto by movement of water, preferably sea waves and/or sea currents, the apparatus comprising two or more interconnected members of which at least one is buoyant and which in use of the apparatus are movable relative to each other due to vertical motions of the water, at least one of said members being provided with or connected to means which in use of the apparatus is responsive to horizontal motions of the water, and means for converting the relative movements of said interconnected members and operation of the means responsive to horizontal motions of the water into useful energy, such as electricity.
[US4210821A]
Patent IE-840751-L (IE)
Title: Adhesive bandage and wrapper
IPC: A61F13/02
Filed: 1984-03-27
Abstract: An adhesive bandage and integral wrapper therefor is constructed of a continuous length of bulky, nonwoven bandage and wrapper material which is preferably a nonwoven fabric batt constructed at least in part of heatfusible fibers. The bandage pad is formed by a Z-fold in the bandage portion of the material. The adhesive wing portions of the bandage are compacted and fused prior to the application of a pressure-sensitive adhesive. The wrapper portion of the product may be entirely nonwoven fabric compacted and heat-fused and coated with an adhesive release surface, or may be formed in part of polyethylene or similar film. The wrapper material is folded around the bandage and sealed on three eges to totally enclose the bandage.
Patent IE-800761-L (IE)
Title: Naphthyridines
IPC: C07D471/04
Filed: 1980-04-15
Abstract: 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives are anti-secretory agents for use in the treatment of peptic ulcer disease.
[US4324893A]
Patent IE-850838-L (IE)
Title: Electrical capacitor
IPC: H01G4/18
Filed: 1985-04-02
Abstract: An electric capacitor formed of dielectric layers provided on at least one side with metal layers with coatings, and wherein the layers are formed of partially crystallized and pre-shrunk polyethylene terephthalate. The coatings are alternately electrically conductively connected to metal layers applied by the Schoop process with opposing polarity to end faces of the capacitor body. The dielectric layers are arranged to form a stack or are deformed to form a flat-pressed winding. The polyethylene terephthalate dielectric layers have a degree of crystallization of at least 50%, in particular at least 55%, measured by differential thermo-analysis in order to determine the melting point enthalpy. In a method for production of such a capacitor, the capacitor bodies provided with the metal layers are subjected to an additional heat treatment in which the temperature is increased from room temperature to a final temperature of 200 DEG  to 250 DEG  C. for 1 to 5 hours. This final temperature is held for a period of 1 to 65 hours, where the length of this holding time is inversely proportional to the final temperature.