baber/WOPTO huggingface dataset:
Patent CA-2433732-A1 (CA)
Title: Crystallizable polylactone copolymers prepared from mono-and di-functional polymerization initiators
Inventor: BEZWADA RAO S
IPC: C08G63/664
Filed: 2003-06-27
Abstract: The present invention is directed to absorbable polylactone copolymers prepared in part from about 2 to about 80 mole percent glycolide, utilizing a combination of a monofunctional polymerization initiator and a di-functional polymerization initiator, to achieve rates of crystallization of the copolymer of at least about 2 times faster than the rate of crystallization of a copolymer made by a similar process utilizing either the mono-functional or the di-functional polymerization initiator alone. Medical devices containing such copolymers are also disclosed.
Patent CA-2433985-A1 (CA)
Inventor: CHEUNG LING YUK
IPC: A23L1/30
Filed: 2003-06-27
Abstract: Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to treat hypertension (e.g., lower blood pressure) in a subject (e.g., a mammal) as a result of having been cultured in the presence of an alternating electric field having a specific frequency and a specific field strength. Also included are methods of making and using such compositions.
Patent CA-2436043-A1 (CA)
Title: Focusable virtual microscopy apparatus and method
Inventor: BACUS JAMES W
IPC: G06F17/30
Filed: 2003-02-24
Abstract: A virtual microscope slide includes images of a specimen for a given level of optical magnification which are associated and stored in a data structure. The forming of the data structure having the multiple Z-plane images preferably includes automatically focusing at a principal reference focal plane and capturing and digitizing an optically magnified reference Z-image and then shifting the specimen relative to the lens system by a predetermined increment to capture and digitize another Z-plane image. Preferably, a multiple sequence of Z-plane images above and below the reference image and captured arid digitized. For ease of retrieval and use, each reference image has its associated Z-plane images are formed in a stack that is sent over the Internet, or Intranet to a local computer storage for quick retrieval when a viewer wants to mimic a focusing up or down to better view a detail in an image. Thus, the resultant images are retrieved and displayed such that a virtual focusing capability is available to the user. The images can be formed with overlapping fields of depth, adjacent fields of depth, or wholly separated fields of depth.
Patent CA-2436415-A1 (CA)
Title: A polyethylene crosslinkable composition
Inventor: COGEN JEFFREY M
IPC: H01B3/44
Filed: 2002-02-27
Abstract: A composition comprising: (a) polyethylene; (b) as a scorch inhibitor, [1,3,5-tris(4-tert-butyl-3-hydrosy-2,6-dimethylbenzyl)-1,3,5,-triazine-2-4-6-(1H,3H,5H)-trione]; (c)a thioester; (d)a hindered amine stabilizer; and (e) an organic peroxide.
Patent CA-2436789-A1 (CA)
Inventor: SHARMA SHUBH D
IPC: C07K5/103
Filed: 2001-12-19
Abstract: The invention provides methods for identification and determination of target-specific folding sites in peptides and proteins, including a method for determining a secondary structure binding to a target of interest within a known parent polypeptide that binds to the target of interest. In one embodiment of the invention, a residue or mimetic containing a nitrogen atom and a sulfur atom available for binding to a metal ion is serially substituted for single residues in or inserted between two adjacent residues in a known primary sequence of a peptide or protein. The resulting sequence, which includes a minimum of the residue or mimetic containing a nitrogen atom and a sulfur atom available for binding to a metal ion and two residues on the amino terminus side thereof, is complexed with a metal ion, thereby forming a metallopeptide. The resulting metallopeptides are then used in binding or functional assays related to the target of interest, and the metallopeptide demonstrating binding or functional activity is selected. The invention further provides methods to determine the specific sequence and local three-dimensional structure of that portion of peptides or proteins that bind to a receptor or target of interest, or mediate a biological activity of interest and methods to determine the pharmacophore of receptors or targets of interest. The invention provides for defined pharmacophores or receptors or targets of interest and directed libraries for identification and determination of target-specific folding sites in peptides and proteins and for identification and determination of pharmacophores of receptors or targets of interest.
Patent CA-2437319-A1 (CA)
Title: Method and apparatus for detecting the synchronization timing of a signal
Inventor: FEBVRE PAUL
IPC: H04J3/06
Filed: 2002-01-30
Abstract: In a frame sync method, a receiver searches for the presence of an N-symbol long unique word pattern. For each possible frame sync detected, the receiver proceeds to demodulation and FEC processing. After each iteration of the FEC  decoder, the detected unique word pattern is compared to the expected one and the frame sync is detected if the number of unique word errors has decreased.
Patent CA-2438628-A1 (CA)
Title: Artificial proteins with reduced immunogenicity
Inventor: HAMILTON ANITA
IPC: A61K39/395
Filed: 2002-02-18
Abstract: The invention relates to artificial modified proteins, preferably fusion proteins, having a reduced immunogenicity compared to the parent non-modifie d molecule when exposed to a species in vivo. The invention relates, above all , to novel immunoglobulin fusion proteins which essentially consist of an immunoglobulin molecule or a fragment thereof covalently fused via its C- terminus to the N-terminus of a biologically active non-immunoglobulin molecule, preferably a polypeptide or protein or a biologically active fragment thereof. In a specific embodiment, the invention relates to fusion proteins consisting of an Fc portion of an antibody which is fused as mentioned to the non-immunological target molecule which elicits biological or pharmacological efficacy. The molecules of the invention have amino acid sequences which are altered in one or more amino acid residue positions but have in principal the same biological activity as compared with the non- altered molecules. The changes are made in regions of the molecules which ar e identified as T-cell epitopes, which contribute to an immune reaction in a living host. Thus, the invention also relates to a novel method of making su ch fusion proteins by identifying said epitopes comprising calculation of T-cel l epitope values for MHC Class II molecule binding sites in a peptide by computer-aided methods.
Patent CA-2438727-A1 (CA)
Inventor: HALL DAVID B
IPC: B81B3/00
Filed: 2001-10-11
Abstract: L'invention porte sur un micro-actionneur bistable form~ de deux tranches silicium sur isolateur fusionn~es au niveau d'une couche ~lectrique de contact, et comportant: un couvercle pr~sentant une rainure en V d~finissant un axe optique; une source de signal optique collimat~ plac~e dans la rainure et couplant un signal optique ~ un port optique situ~ dans la rainure; un ~l~ment de transfert; une surface de miroir plac~e sur l'~l~ment de transfert et bloquant ou r~fl~chissant le signal optique. L'~l~ment de transfert pr~sente un point de support ~ sa premi­re et ~ sa deuxi­me extr~mit~. La partie centrale de l'~l~ment de transfert comporte un miroir se d~pla×ant avec l'~l~ment de transfert ~ partir de l'axe de compression vers un premier et un deuxi­me ~tat incurv~. Le miroir bloque ou refl­te l'axe optique. Une structure dilatable applique une force de compression entre le premier et le deuxi­me point de support le long de l'axe de compression pour maintenir l'~l~ment de transfert dans le premier ou le deuxi­me ~tat incurv~. La partie centrale de l'~l~ment de transfert passe du premier ~tat incurv~ au deuxi­me ~tat incurv~ en traversant l'axe de compression pour d~gager l'axe optique.
Patent CA-2439613-A1 (CA)
Title: Appareil rotatif et methode de fonctionnement
Inventor: BODNAR ERNEST R
IPC: B21D28/36
Filed: 2003-06-27
Abstract: L'invention concerne un appareil rotatif (10) comprenant un premier assemblage rotatif de matrice (12) et un second assemblage rotatif de matrice (14) agencés, juxtaposés l'un à l'autre, sur des premier et second côtés respectifs du trajet de déplacement d'une bande de pièce à usiner, et fonctionnant de concert afin de réaliser des opérations sur une pièce à usiner (w) passant entre eux, chaque assemblage de matrice (12, 14) comportant un rotor principal (26, 28), monté rotatif, au moins un corps support de matrice (42), supporté par le rotor principal (26, 28), déportable par rapport au rotor principal (26, 28), des cames de commande (108, 110), connectées au corps support de matrice (42), des guides de came (100, 102, 104, 106), destinés à l'engagement des cames de commande (108, 110), et des paliers de corps support de matrice (54) montés sur le rotor principal (26, 28) destinés à supporter ce corps (42). Le corps support de matrice (42) peut se caler automatiquement sur la vitesse linéaire de la pièce à usiner (w), avant et après le contact. La matrice (50A, 50B) peut comporter une portion mobile (74) qui se déplace à l'intérieur ou à l'extérieur afin de réaliser une opération sélective sur la pièce à usiner (w). Les rotors principaux (26, 28) sont connectés par un train d'engrenages d'entraînement (22,24) avec réglage de rattrapage de jeu (138). Le procédé d'opération sur une pièce à usiner (w) permet de produire, sur la pièce à usiner (w), une série continue de formations et d'éviter la production de formations à des intervalles désirés afin de produire des longueurs recherchées.
Patent CA-2439863-A1 (CA)
Title: Storage container for liquids hazardous to water
Inventor: WYCHLACZ WERNER
IPC: B65D90/02
Filed: 2002-03-05
Abstract: The invention relates to a storage container for water-endangering liquids that comprises a leakage detection and restraint system. The aim of the invention is to provide a container that allows for a short-notice alarm system and that minimizes the collection volume, that is to ensure that the water-endangering liquid spreads as little as possible, as well as to reduce construction and maintenance costs. To this end, the storage container is characterized by the following features: a gutter (4) surrounding the tank (13) that is directly contiguous with the outer wall (2) of the storage container and that collects leaked liquid, at least one gutter outlet (14), at least one liquid collection container (6), and at least one detection system (12) for the water-endangering liquids. The gutter outlet (14) is adapted to guide the liquid collected in the gutter (4) to the liquid collection container (6) that is provided with the detection system (12).
Patent CA-2440075-A1 (CA)
Title: Advanced method and system for handling missed mobile calls
Inventor: SEIFERTH FRANK
IPC: H04M3/42
Filed: 2003-09-05
Abstract: The advanced method and system for handling missed mobile calls represents a progress in the art which allows wireless subscribers to be notified by any addressable, asynchronous delivery mechanism, including Short Message Service (SMS), Multimedia Messaging Service (MMS) and E-mail among others, when incoming telecommunications are missed as when they are otherwise unreachable (for instance, when the wireless device is turned off or outside coverage area) or busy. The notification would include the Calling Party Number, among other configurable variables, as to enable subscribers to the service to subsequently return the call to the originating party.
Patent CA-2442708-A1 (CA)
Title: Method for the diagnosis of alzheimer's disease and other prion related disorders
Inventor: SMALL DAVID HENRY
IPC: G01N33/68
Filed: 2002-01-23
Abstract: The invention provides a method for the diagnosis of dementia and transmissible spongiform encephalopathies in a subject by detecting the levels of glycoproteins that bind wheat germ agglutinin. The invention also provides a method for diagnosis of dementia and transmissible spongiform encephalopathies in a subject by comparing the levels of glycoproteins that bind wheat germ agglutinin with the glycosylation patterns of biomarkers, acteylcholinesterase and butyrylcholinesterase.
Patent CA-2444106-A1 (CA)
Title: Ventilation apparatus with integral intumescent fire and smoke stop and method of manufacturing same
Inventor: LENTINI JEFFREY
IPC: F24F7/06
Filed: 2003-10-03
Abstract: An improved ventilation assembly for preventing fire and smoke from undermining a fire rated surface. The ventilation assembly includes a housing having at least one side wall defining an interior space, and a top wall coupled to the side wall, with an inlet adjacent the at least one side wall and an outlet coupled to the housing. A fluid, such as air, flows between the inlet and the outlet. A fire shielding material is disposed within the interior space, where the fire shielding material expands upon the application of a predetermined amount of heat such that the fire shielding material obstructs the flow of the fluid between the inlet and the outlet.
Patent CA-2447768-A1 (CA)
Inventor: KORTENBACH JUERGEN A
IPC: A61B17/068
Filed: 2002-06-03
Abstract: An endoscopic surgical instrument for deploying a two part fastener having a male fastener part and a female fastener part, includes a tube having a proximal end and a distal end. An end effector is coupled to said distal end of said tube and is configured to hold the male fastener part and the female fastener part in opposed relation. An actuator is coupled to said proximal end of said tube and is configured to actuate the end effector. A shearing device may be positioned proximate the end effector to shear off a tip of the male fastener part after the male and female fastener parts are moved into locking relation. In addition, the surgical instrument may include a male fastener part having a shaft with a plurality of detent positions. Further, the male fastener part may include a base and a shaft pivotally connected to the base.
Patent CA-2450937-A1 (CA)
Inventor: STEFAS ELIE
IPC: G01N33/68
Filed: 2002-07-02
Abstract: The invention concerns a method for separating and/or detecting and/or identifying and/or quantifying in a biological material at least a prion protein (PrP), characterised in that it comprises a step which consists in separating and/or detecting and/or identifying and/or quantifying a (PrP/beta2GPI) complex consisting of at least a prion protein bound to at least a form of beta2GPI.
Patent CA-2452832-A1 (CA)
Title: Essai de criblage in vitro de la .gamma.-secretase
Inventor: KOSTKA MARKUS
IPC: A61P25/28
Filed: 2002-06-27
Abstract: L'invention concerne un procédé de criblage dans lequel des substances pouvant moduler l'activité de la .gamma.-sécrétase sont identifiées par incubation d'une source et d'un substrat d'activité de .gamma.-sécrétase avec une substance d'essai, et par détection d'un fragment C-terminal libéré à partir dudit substrat.
Patent CA-2454651-A1 (CA)
Inventor: UNGAR JEFFREY E
IPC: H01S5/0625
Filed: 2003-03-03
Abstract: L'invention porte sur un laser à semi-conducteur comportant une section de laser à rétroaction et une section d'amplification. La section de laser à rétroaction produit un faisceau laser présentant une intensité maximale pour une première longueur d'onde, que la section d'amplification transforme en faisceau de forte puissance. La section d'amplification présente un pic de gain optique pour une deuxième longueur d'onde décalée par rapport à la première. Ce décalage donne un faisceau de sortie présentant une largeur de raie beaucoup plus étendue que celle de la section de laser à rétroaction seule. Ladite largeur de raie est relativement stable même si une partie de la lumière se rétro-reflète dans le laser à semi-conducteur.
Patent CA-2455836-A1 (CA)
Title: Method and device for predicting the fertile phase of women
Inventor: MARETT DOUGLAS MICHAEL
IPC: A61B10/00
Filed: 2002-07-29
Abstract: A method and device to predict ovulation in a female human by measuring changes in the concentration of a number of ions in eccrine sweat is disclosed. The concentration, or changes in concentration, of one or more io ns are determined throughout the day and analyzed against predetermined pattern s in order to predict ovulation one to five days in advance. This permits the user to more accurately determine commencement of the fertile phase, which f or female humans is generally considered to be about four days prior to ovulati on to one day after ovulation. The concentration of the ions measured include sodium (Na+), potassium (K+), ammonium (NH4+), calcium (Ca2+), chloride (Cl- ) and nitrate (NO3-). To further increase the accuracy of the reading, a large number of readings can be obtained throughout a day and statistically analyz ed to determine the change over time. In addition, the concentration of two or more ions can be obtained to increase accuracy. Ratiometric measurements between two or more ions can be determined to increase accuracy and account for ion accumulation on the skin. Ratiometric measurements between ammonium (NH4+) and calcium (Ca2+) have been found to provide more distinct patterns because the concentration of these two ions change in opposite directions during the relevant period preceding ovulation.
Patent CA-2456081-A1 (CA)
Inventor: PLACE J WAYNE
IPC: F24F13/06
Filed: 2004-01-27
Abstract: An energy efficient air distribution system placed within the conditioned space of a building comprising a duct having an interior volume for conducting air.      One of the exterior surfaces may have an ornamental design providing the impression the device is actually cornice molding. An opening extends through the duct wall for releasing conditioned air from the duct interior into the conditioned space. Opening is positioned on the duct to be visibly obscured. In one embodiment, a flow control mechanism is positioned adjacent to the opening for controlling the amount of conditioned flowing through the opening.
Patent CA-2457669-A1 (CA)
Title: Autonomous weapon system
Inventor: GREENE BEN A
IPC: F41G3/16
Filed: 2001-10-17
Abstract: An autonomous weapon system including weapon (9) and weapon mounting system (7, 8) operable to point the weapon (9) in accordance with input control signals. The weapon system includes a sensor (2) to acquire images and other data from a target zone and an image processor (3) to process acquired image data and identify potential targets (1) according to predetermined target identification criteria. Targeting system (4, 5) provides input control signals to the weapon mounting system (7, 8) to point the weapon (9) for firing at potential targets (1). A control system operates targeting system (4, 5) and fires the weapon (9) at selected targets (1) according to a predetermined set of rules of engagement. The rules of engagement include combat, peacekeeping or policing scenarios. Remotely located operator (10) may amend the rules of engagement, or override the control system as required.
Patent CA-2458669-A1 (CA)
Inventor: SITNIK-NIETERS THERESA ANN
IPC: G01T1/20
Filed: 2002-08-21
Abstract: L'invention concerne un système (20) d'imagerie par rayonnement comprenant un scintillateur (26), un réseau (30) imageur et une couche (22) de lamination. La couche (22) de lamination fixe et couple de manière optique le scintillateur (26) au réseau (30) imageur. La couche (22) de lamination comprend un matériau de lamination ne contenant sensiblement pas d'espaces vides. La mise au point d'un système (20) d'imagerie par rayonnement consiste à déposer une couche (22) de lamination entre un imageur lumineux (24) et un scintillateur (26) pour former un sous-ensemble (150). L'imageur lumineux (24) comprend un réseau (30) imageur, une surface (34) de plaque d'imagerie et une pluralité de plots (32) de contact. Des étapes supplémentaires consistent à mettre le sous-ensemble (150) sous vide; à chauffer le sous-ensemble (150) à une température de liaison, exerçant une force de liaison sur le sous-ensemble (150), maintenant le vide, la température de liaison et la force de liaison jusqu'à ce que l'imageur lumineux (24) soit fixé au scintillateur (26), la couche (22) de lamination comprenant un matériau de lamination ne contenant sensiblement pas d'espaces vides.
Patent CA-2459164-A1 (CA)
Inventor: SLAVTCHEFF CRAIG STEPHEN
IPC: A61K8/00
Filed: 2002-08-30
Abstract: A cosmetic composition is provided which includes an organic sunscreen agent , a water-insoluble polymeric powder of porous particles, and an aqueous syste m wherein pH is less than 7. The porous particles remove the tackiness normall y associated with organic sunscreen agents and low pH systems thereby providin g a resultant composition of excellent skinfeel.
Patent CA-2459512-A1 (CA)
Title: Rotary tool
Inventor: COLANGELO LOUIS J III
IPC: B25B21/02
Filed: 2004-03-04
Abstract: A rotary tool, such as an impact wrench, includes a housing having a forward end and supporting a motor. The motor has a motor shaft extending axially through the housing and defining an axis. The rotary tool further includes a frame coupled to the motor shaft and rotatable relative to the housing about the axis in response to rotation of the motor shaft. The frame defines an interior space. The rotary tool also includes a piston supported by the frame and moveable axially in the interior space and an output shaft supported in the forward end of the housing and rotatable about the axis. The output shaft has a plurality of cams. The piston is engageable with the plurality of cams to intermittently hammer the output shaft.
Patent CA-2460665-A1 (CA)
Inventor: TRIEBEL FREDERIC
IPC: C12N15/09
Filed: 2002-09-17
Abstract: L'invention concerne des molécules se liant avec des cibles spécifiques qui comprennent des motifs Glu-Pro (EP) répétés. Il s'agit de molécules se liant avec une cible dans laquelle on trouve un motif EP de séquence [X- (EP)¿n?-Y-(EP)¿m?-Z]¿p?. Dans cette séquence, X, Y et Z, identiques ou différents, comprennent une séquence de 0 à 10 aides aminés, identiques ou différents; n et m son des entiers valant entre 0 et 20, de préférence entre 3 et 10, sachant qu'au moins l'un des entiers n ou m est différent de 0; et p est un entier compris entre 1 et 10. L'invention concerne également des compositions pharmaceutiques renfermant ces molécules, des anticorps vis-à-vis des molécules en question, et des procédés utiles pour le criblage de médicaments via lesdites molécules.
Patent CA-2462033-A1 (CA)
Title: Procede de formation d'une bande continue pour un separateur de type a bande
Inventor: WHITLOCK DAVID R
IPC: F16G1/00
Filed: 2002-09-27
Abstract: L'invention concerne une bande formée de première et seconde parties d'une feuille thermoplastique comportant, respectivement, des première et seconde pluralités de languettes montées à l'écart pour former des première et seconde pluralités d'ouvertures le long des premier et second bords correspondants des première et seconde parties de la feuille thermoplastique, la première pluralité de languettes étant reliées à la seconde pour joindre le premier bord au second bord. Par ailleurs, l'invention concerne un procédé de formation d'une bande en matériau thermoplastique, consistant d'abord à former des angles sur le premier bord de la première partie de la feuille thermoplastique ainsi que sur le second bord de la seconde partie de la feuille thermoplastique, à pratiquer ensuite des première et seconde pluralités d'ouvertures, respectivement, dans les première et seconde parties de la feuille thermoplastique, à placer ensemble les premier et second bords de façon à ce qu'ils se chevauchent, et enfin, à relier ensemble les première et seconde parties de la feuille thermoplastique.