baber/WOPTO huggingface dataset:
Patent CA-2629777-C (CA)
Inventor: BERK SCOTT C
IPC: A61P35/00
Filed: 2006-11-17
Granted: 2011-08-16
Abstract: The present invention relates to a novel class of substituted spirocyclic compounds, represented by the following structural Formula: I Wherein A, B and D are independently selected from CR1 2, NRla, C(O) and O; E is selected from a bond, CR1 2. NR1 a, C(O) and O; wherein at least one of A, B, D or E is CR1 2; and provided that when A is O, then E is not O; G is CRl 2; R is selected from NH2 and OH; These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing termin differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the compounds of the instant invention and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of these compounds in vivo.
Patent CA-2632780-C (CA)
Title: Combinaison de r,r-glycopyrrolate, de rolipram et de budesonide pour le traitement de maladies inflammatoires
Inventor: MAUS JOACHIM
IPC: A61P17/06
Filed: 2006-12-01
Granted: 2013-11-12
Abstract: La présente invention concerne de nouvelles combinaisons d'anticholinergiques, d'agonistes de récepteur .beta.2-adrénergique, d'inhibiteurs des PDE 4, de glucocorticoïdes, et d'antagonistes du récepteur de leucotriène, un procédé pour leur production et leur utilisation dans le traitement de maladies inflammatoires, de préférence de maladies respiratoires telles que l'asthme et les bronchopneumopathies chroniques obstructives (COPD) ou de maladies auto-immunes.
Patent CA-2637173-C (CA)
Inventor: SWANIKER HANSEN
IPC: C08J9/00
Filed: 2007-01-31
Granted: 2015-12-01
Abstract: Super-soft foam materials, optionally for use as medical dressings (200), are provided. The pads are made of a foam prepared from NCO-terminated prepolymers in combination with an aqueous phase including fatty alcohols and alkyl polysaccharides. The foam may optionally contain at least one medicinal agent.
Patent CA-2642835-C (CA)
Inventor: KAWAHARA TETSUYA
IPC: C07D405/14
Filed: 2006-10-13
Granted: 2014-12-02
Abstract: La présente invention a pour objet des sels de 2-[({4-[(2,2-diméthyl-1,3-dioxann-5-yl)méthoxy]-3,5-diméthylpyridin-2-yl}méthyl)sulfinyl]-1H-benzimidazole, ainsi que les cristaux et les formes amorphes desdits sels.
Patent CA-2645852-C (CA)
Inventor: DANLEY THOMAS J
IPC: H04R25/00
Filed: 2007-03-14
Granted: 2013-12-24
Abstract: A sound reproduction system (10) is disclosed in which a sound barrier (14) defines a horn passageway having an upstream (22) and a downstream section (24). A driver (12) is mounted at the throat (16) of the upstream section (22) so that its rearward directed output communicates with the downstream section (24). Output from the upstream section and the rearward directed output of the driver are merged at a tap point located at the beginning of the downstream section. By altering the respective areas and lengths of the upstream and downstream sections a variety of different frequency dependent responses are obtained. In one example, low-frequency response systems of heretofore unobtainable compact size are realized.
Patent CA-2647936-C (CA)
Title: Composition de liquide a lustrer et kit
Inventor: SCHULTZ MICHAEL A
IPC: C09G1/12
Filed: 2007-03-27
Granted: 2014-08-05
Abstract: L'invention concerne une composition de liquide à lustrer adaptée pour le lustrage d'une automobile et similaire comprenant entre environ 0,01 et environ 3 pour cent en poids d'au moins une cire à base de silicone, entre environ 0,20 et environ 10 pour cent en poids de composés de polyalphaoléfine, y compris entre environ 0,1 et environ 5 pour cent en poids d'au moins une polyalphaoléfine hyper-ramifiée, entre environ 6 et environ 60 pour cent en poids d'au moins un fluide de silicone polydiméthylsiloxane, entre environ 1 et environ 20 pour cent en poids d'au moins un silicone cyclique volatile, entre environ 0,25 et environ 3 pour cent en poids d'au moins un silicone amino-fonctionnel, entre environ 0,01 et environ 5 pour cent en poids d'au moins un absorbeur UV et un support provenant du pétrole à cet effet. La composition de liquide à lustrer peut être conditionnée avec un chiffon à lustrer en microfibre sous la forme d'un kit de lustrage. La composition de liquide à lustrer permet d'obtenir un poli durable de qualité professionnelle et peut être utilisée directement sur les composants en caoutchouc, en vinyle et en plastique sans laisser de résidus blancs, souvent associés aux compositions à lustrer conventionnelles.
Patent CA-2648130-C (CA)
Inventor: ROCH EVELYNE
IPC: H04L29/08
Filed: 2006-06-30
Granted: 2013-10-15
Abstract: An aspect of the present invention provides a method of establishing call controller communication in a multi-layer transport network where a plurality of signaling communications networks may exist within each layer. An interlayer call controller association is enhanced to provide associations of multiple client call controllers to a single server layer call controller. A method of collecting sets of associations related to a single server layer call is provided so that a sequence of client call controllers may be constituted. The plurality of signaling communications networks is then used to pass control information between call controllers in that sequence.
Patent CA-2651832-C (CA)
Inventor: ABBOUD MARWAN
IPC: A61B18/02
Filed: 2002-01-25
Granted: 2013-06-25
Abstract: A cryogenic medical system includes a medical device and a console connectable to the medical device at a connection point. The console controls the temperature of the medical device. The console includes a first cooling system directing coolant to the medical device at a first temperature along a coolant supply line and a second cooling system chilling the coolant within the coolant supply line to a temperature below the first temperature before the coolant reaches the connection point.
Patent CA-2655582-C (CA)
Inventor: AMIRAL JEAN
IPC: G01N33/53
Filed: 2007-06-25
Granted: 2014-12-30
Abstract: The invention relates to a method for the detection of heparin-dependent antibodies and the diagnosis of immune or autoimmune pathologies potentiated by a heparin substance, such as thrombocytopenia induced by heparin (HIT type II) as inducer drug. The invention is characterized in that said method comprises the steps consisting in: 1) reacting: at least one substance with high affinity for a heparin substance (SFA), consisting of any molecule or complex having a high affinity for a heparin substance, with at least one heparin substance (SH) so as to form a substance with high affinity for heparin-heparin substance (SFA-SH) complex, wherein the heparin substance is in slight or large excess, so as to be able to bind other substances with affinity for heparin; then with at least one potential antigenic substance capable of reacting with the heparin substance, thus forming a complex (Ag-SH); and, finally, with the plasma or the serum of a patient to be tested (preferably diluted to a dilution of the order of 1:100) potentially containing: an anti(Ag-SH) antibody material generated in the organism after administration of a heparin substance, and/or at least one immune complex consisting of an Ag-SH/anti(Ag-SH) antibody complex present in the plasma or serum of the patient capable of reacting with the substance with high affinity for the heparin substance-heparin substance (SFA-SH) complex, and then, 2) revealing the resulting (Ag-SH)-anti(Ag-SH) complex produced.
Patent CA-2655592-C (CA)
Title: Endless belt drive for vehicle
Inventor: MALLETTE BERTRAND
IPC: B62D9/00
Filed: 2005-12-21
Granted: 2010-09-21
Abstract: An endless belt system for a vehicle having a negative trail steering geometry is provided. The endless belt system replaces the wheels that steer a vehicle, particularly an all-terrain vehicle, to provide increased floatation over soft terrain. Also provided is a lower portion of an endless belt supported by a rail providing pivotal support to the contact area to increase response of the, endless belt system to uneven terrain. Also provided is a stopper to limit the steering angle of the endless belt system that is disposed on the vehicle such that a steering linkage of the vehicle does not bear a force created when the stopper is engaged.
Patent CA-2661388-C (CA)
Title: Device for grains dosing with air sealing
Inventor: ESTEVE VICTOR
IPC: B65D83/04
Filed: 2007-06-15
Granted: 2011-08-09
Abstract: Device for grains dosing with air sealing, comprehending a molded packaging in a way that the product within is not in direct contact with the air outside and is totally hermetical when closed, preserving its physical and chemical characteristics, therefore it is conformed basically by five pieces being one lid (1A), a container/bottle (2A), a mobile acting element (3A), a spring (4A) and a passage element (5A)1 where said lid (1A) is connected to a mobile sealing element, conformed by the container/bottle (2A), containing a fixed passage element (5A) at its top portion which may be connected to or screwed and at its bottom portion it is conformed the inlet (6A) of the dosing element; at the bottom portion of the body (1A) is provided a guide (7A) for the accommodation of the acting element (3A).
Patent CA-2663578-C (CA)
Inventor: KRAIMER JAMES V
IPC: G08C17/02
Filed: 2007-09-14
Granted: 2016-05-03
Abstract: A supplemental control system for a materials handling vehicle comprises a wearable control device, and a corresponding receiver on the materials handling vehicle. The wearable control device is donned by an operator interacting with the materials handling vehicle, and comprises a wireless transmitter and a travel control communicably coupled to the wireless transmitter. Actuation of the travel control causes the wireless transmitter to transmit a first type signal designating a request to advance the vehicle in a first direction. The receiver is supported by the vehicle for receiving transmissions from the wireless transmitter. A traction control of the vehicle is responsive to a receipt of the first type signal by the receiver to cause the vehicle to advance.
Patent CA-2664826-C (CA)
Inventor: YANG DAVID J
IPC: A61P35/00
Filed: 2007-07-02
Granted: 2015-09-29
Abstract: Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
Patent CA-2667529-C (CA)
Inventor: CEFAI JOSEPH JOHN
IPC: F04B35/00
Filed: 2007-10-25
Granted: 2014-10-21
Abstract: An actuator comprises a cavity (2) containing a working medium (3) that reversibly expands as it undergoes a phase change from a solid to a liquid state, a diaphragm (4) disposed adjacent the cavity such that expansion and contraction of the expandable working medium causes the diaphragm to deflect, and a semiconductor element (6) disposed in the cavity, wherein the semiconductor element is adapted to heat the working medium to cause it to undergo the phase change into the liquid state. The actuator may be used in a pump for an infusion system.
Patent CA-2670072-C (CA)
Inventor: UENO TAKAHITO
IPC: G03G21/16
Filed: 2007-12-25
Granted: 2015-09-15
Abstract: A rotating force transmitting part for a photosensitive drum for a main assembly of an image forming apparatus, wherein the main assembly includes a driving shaft having a rotating force applying portion including a coupling member capable of taking a rotational force transmitting angular position for transmitting the rotational force to the drum and a disengaging angular position in which the coupling member is inclined away from the axis of the drum from the rotational force transmitting angular position, wherein when the drum is dismounted from the main assembly in a direction perpendicular to the axis of the drum, the coupling member moves from the rotational force transmitting angµlar position to the disengaging angular position.
Patent CA-2670741-C (CA)
Title: Combinaison d'inhibiteur de l'histone-deacetylase et d'inhibiteur metabolique
Inventor: ATADJA PETER WISDOM
IPC: A61K45/06
Filed: 2007-11-30
Granted: 2016-04-12
Abstract: L'invention concerne une combinaison qui comprend : (a) un HDAI; et (b) un antimétabolite, pour un usage simultané, concurrent, séparé ou séquentiel, en particulier pour un usage dans le traitement de maladies prolifératives, plus particulièrement le MDS (Syndrome Myélodysplasique) ou l'AML (Leucémie Myéloïde Aiguë). L'invention concerne ainsi des compositions pharmaceutiques, comprenant une telle combinaison, et un procédé de traitement du MDS et de l'AML chez les mammifères, en particulier chez l'homme, avec une telle combinaison. La présente invention concerne en outre un conditionnement commercial ou un produit comprenant une telle combinaison.
Patent CA-2672331-C (CA)
Title: Method, system and apparatus for provisioning a communication client
Inventor: CLARK DAVID WILLIAM
IPC: H04L12/16
Filed: 2006-12-14
Granted: 2016-10-04
Abstract: According to embodiments of the present invention, there is provided a method, system and apparatus for provisioning a communication client. The method comprises receiving via a communication network a request from the communication client. The method further comprises determining a positioning object associated with the communication client. The method further comprises, based on the positioning object, determining a subscription profile associated with the communication client. The method further comprises, based on the subscription profile, compiling a configuration file.
Patent CA-2681180-C (CA)
Inventor: ANDREOLETTI GILBERT
IPC: A61K51/10
Filed: 2008-03-18
Granted: 2014-07-08
Abstract: The invention relates to a process for producing 228Th from a natural thorium salt, which comprises in succession: a) the separation of the radium from the other radioelements present in this salt, by at least one coprecipitation of the radium by barium sulphate, this coprecipitation comprising: i) the addition of sulphuric acid and a barium salt to an aqueous solution of said natural thorium salt in order to form a barium-radium sulphate coprecipitate and ii) the separation of the coprecipitate from the medium in which it has formed; b) the extraction of the thorium 228 coming from the decay of radium 228 from the coprecipitate thus separated; and, optionally c) the purification and concentration of the 228Th thus extracted. Applications: manufacture of radiopharmaceutical products useful in nuclear medicine, in particular in radioimmunotherapy for the treatment of cancers and AIDS.
Patent CA-2684669-C (CA)
Title: Ameliorations pouvant etre apportees a des machines de preparation de boissons et a leurs cartouches
Inventor: TANNER ROGER GEOFFREY
IPC: A47J31/06
Filed: 2008-05-16
Granted: 2013-11-05
Abstract: La présente invention concerne une tête de distribution d'une machine de préparation de boissons comprenant : un orifice d'admission orienté vers le haut pour amener l'eau vers une cartouche reçue dans la tête de distribution; un orifice d'évacuation orienté vers le bas pour faire sortir la boisson; un lecteur de code à barres comportant une fenêtre par laquelle peuvent être émis des signaux. L'orifice d'admission, l'orifice d'évacuation et la fenêtre du lecteur de code à barres sont alignés sur l'orifice d'évacuation se trouvant entre l'orifice d'admission et la fenêtre du lecteur de code à barres.
Patent CA-2684844-C (CA)
Inventor: MARSHALL DALE
IPC: E02D27/32
Filed: 2009-11-09
Granted: 2012-06-26
Abstract: There is described a wall structure for absorbing or transferring heat from or to the ground, the wall structure comprising a footing for the wall structure disposed in the ground below grade extending in the longitudinal direction of the wall structure, a vertical wall supported on and extending longitudinally in the direction of the footing, the vertical wall extending upwardly from the footing above grade to a predetermined height, and having upper, lower, interior, exterior and end surfaces, a sheath of insulation for enveloping the vertical wall's upper, end, interior and exterior surfaces and thermal conductors disposed in the wall structure to be in thermal communication with one another, at least some of the conductors extending outwardly from the footing into the ground, the thermal conductors facilitating heat transfer between the ground and the vertical wall.
Patent CA-2686168-C (CA)
Title: Dispositif et procede de commande de configuration d'ecran pour des contenus telediffuses captes par un recepteur de tele numerique
Inventor: AHN TAE-MIN
IPC: H04N21/643
Filed: 2009-11-17
Granted: 2015-10-13
Abstract: Linvention concerne une méthode et un appareil permettant de transmettre à un système de radiodiffusion numérique les données de diffusion reçues. Lappareil permettant de commander une configuration décran, dans un récepteur de radiodiffusion numérique, comprend ceci : une unité de réception et de conversion des données qui reçoit des données de tête, notamment les données de configuration du contenu de film en treillis envoyé par un réseau de radiodiffusion et qui convertit les données reçues en données de configuration décran de contenu; et une unité de configuration décran de contenu qui permet déditer les données de configuration décran de contenu converties par lunité de réception et de conversion des données; de disposer les données de configuration décran de contenu selon chaque catégorie dun élément daffichage dun terminal utilisateur; et deffectuer une opération de commande de façon à ce que la première catégorie et la dernière catégorie, parmi les multiples catégories affichées sur lélément daffichage, soient raccordées et affichées de façon cyclique.
Patent CA-2686819-C (CA)
Title: Outboard motor
Inventor: INABA TAKESHI
IPC: F02M35/10
Filed: 2009-12-02
Granted: 2012-01-10
Abstract: An outboard motor S has an upstream intake silencer with an upstream expansion chamber, and a downstream intake silencer disposed under the upstream intake silencer. The upstream expansion chamber has a lower wall of a stepped shape including a raised part overlapping the downstream intake silencer in a plane and a lowered part without overlapping with the downstream intake silencer in a plane and at a level lower than that of the raised part. An upstream outlet passage of the upstream intake silencer is formed in the raised part. The downstream intake silencer has a stepped upper wall having a raised part, and a lowered part underlying the lower wall of the upstream expansion chamber in a plane and extending at a level lower than that of the raised part. A downstream inlet passage of the downstream intake silencer is formed in the lowered part of the upper wall. The respective stepped shapes complementary to each other of the lower wall of the upstream intake silencer and the upper wall of the downstream intake silencer are utilized for enhancing the intake noise reducing effect of the intake silencers and for forming the outboard motor in reduced vertical size by compactly stacking up the intake silencers.
Patent CA-2688992-C (CA)
Title: Procede et systeme pour la conversion des messages d'initiation de session
Inventor: CLARK DAVID WILLIAM
IPC: H04L12/66
Filed: 2009-12-22
Granted: 2013-11-19
Abstract: Une entité de réseau comprenant une entrée pour recevoir un dispositif IP donné, un message d'initiation de session pour lancer une session de communication sur un réseau à base de paquets à l'aide d'un message d'initiation de session généré conformément à un protocole particulier d'initiation de session et une entité de traitement. L'entité de traitement est fonctionnelle pour détecter une caractéristique associée au dispositif IP donné, déterminer, au moins en partie selon la caractéristique associée au dispositif donné, un module d'interface donné d'une pluralité de modules d'interface pour le traitement du message d'initiation de session généré selon le protocole particulier d'initiation de session et entraîner le premier message d'initiation de session selon le protocole particulier d'initiation de session à être traité par le module d'interface donné pour convertir le premier message d'initiation de session dans un deuxième message d'initiation de session généré selon un protocole prédéterminé d'initiation de session.
Patent CA-2689447-C (CA)
Inventor: KEMP DOUGLAS ROY
IPC: B01J19/12
Filed: 2005-12-19
Granted: 2013-02-12
Abstract: An apparatus for irradiation of fluid with electromagnetic radiation, and in particular to an apparatus for irradiation of blood or other body fluids with ultraviolet radiation is provided. The apparatus comprises a housing having disposed therein at least one mount adapted for receiving an ultraviolet radiation source and at least one holder adapted for receiving a container of the fluid. The housing is adapted for operability between a first position, wherein the container may be placed in the holder and a second position, wherein the housing may form a capsule. The apparatus further comprises a control assembly for powering the ultraviolet radiation source. At least a portion of the inner surface of the housing is capable of reflecting the ultraviolet radiation.
Patent CA-2694341-C (CA)
Title: Vermin poison
Inventor: KNOX RICHARD
IPC: A01P11/00
Filed: 2007-09-28
Granted: 2013-04-30
Abstract: Use of an orally or nasally available formulation of Tretazicar for poisoning vermin. An orally available or nasally available formulation of Tretazicar, wherein in the orally available formulation the Tretazicar is protected from acid hydrolysis, and provided that the formulation is not solid Tretazicar in a gelatin capsule. A  formulation of Tretazicar in which the Tretazicar is protected from acid hydrolysis, wherein the formulation is present in a liquid form. A combination of Tretazicar and bait. A method of poisoning vermin comprising making available to the vermin an orally or nasally available formulation of Tretazicar and allowing the vermin to ingest or inhale the formulation of Tretazicar.
Patent CA-2696454-C (CA)
Inventor: CONWAY SCOTT T
IPC: E03B9/02
Filed: 2010-03-12
Granted: 2014-04-15
Abstract: A ball valve cartridge is disclosed. It is especially well suited for freezeless hydrant applications and any other application where it is positioned remotely from a handle or other actuating element. The cartridge contains a ball valve element and an internal stem with a key for rotating the ball valve element between open and closed positions. The stem has rotational stop elements that limit rotational movement of the stem and the ball valve element. In a yard hydrant application, a drain valve can be added to regulate the opening and closing of the drain hole. It has an operational range of a quarter turn or ninety degrees.