baber/WOPTO huggingface dataset:
Patent DE-69311887-D1 (DE)
Inventor: MOHACSI ERNO
IPC: A61P25/00
Filed: 1993-12-20
Granted: 1997-08-07
Abstract: The use of a compound of the formula: <CHEM>  wherein R<2> is aryl, heteroaryl or a group of the formula R<2><0> <CHEM> and R<1> is hydrogen, alkyl, a group of the formula -C(Y,Y<1>)CH2OH or -CH2W, wherein one of Y and Y<1> is hydrogen and the other is alkyl or both Y and Y<1> are alkyl and W is cycloalkyl, aryl or allyl and pharmaceutically acceptable salts thereof, for the manufacture of a medicament for reducing adverse effects of toxic injury to central neurons, particularly wherein the injury to central neurons is associated with ischemia, hypoxia, hypoglycemia, epilepsy, Huntington's disease or Alzheimer's disease, or for treating convulsions. The novel compounds of formula I wherein R<2> is substituted or unsubstitued pyridyl, thiazolyl, thienyl, phenyl, or a group of the formula R<2><0> and R<1> is hydrogen, alkyl, or a group of the formula -C(Y, Y<1>)CH2OH, wherein one of Y and Y<1> is hydrogen and the other is alkyl or both Y and Y<1> are alkyl, provided that when R<2> is pyridyl or phenyl, R<1> is other than alkyl, and pharmaceutically acceptable salts thereof.
Patent DE-69314118-D1 (DE)
Inventor: SKREBERGENE NILS
IPC: B21C37/12
Filed: 1993-03-03
Granted: 1997-10-30
Abstract: PCT No. PCT/GB93/00438 Sec. 371 Date Nov. 4, 1993 Sec. 102(e) Date Nov. 4, 1993 PCT Filed Mar. 3, 1993 PCT Pub. No. WO93/17803 PCT Pub. Date Sep. 16, 1993.A cutting apparatus usable in a machine having a forming head for helically winding a metal strip into a helically wound metal tubing and for issuing the helically wound metal tubing along a defined path. The apparatus includes a first mounting for supporting the forming head, and a carriage guided and longitudinally movable along the first mounting in a direction of travel parallel to the defined path. A cantilever boom has one end mounted to a first end of the carriage and a free end opposite to the one end. The boom extends generally parallel to the direction of travel. A cutting blade is connected to the free end of the cantilever boom and extends in a plane generally perpendicular to the direction of travel. A second mounting is guided with the carriage and is extendible in a direction generally perpendicular to the direction of travel. A rotary shaft is carried by the second mounting. A cutting wheel is mounted to the rotary shaft and extends in the plane generally perpendicular to the direction of travel to cooperate with the cutting blade. The cutting wheel is movable both toward and away from the cutting blade to penetrate a wall of the helically wound metal tubing interposed therebetween. A driving motor with a drive shaft is mounted on a second end of the carriage. A universally jointed transmission shaft couples the rotary shaft to the drive shaft of the driving motor and allows for the extending of the second mounting.
Patent DE-69325566-D1 (DE)
Inventor: KAHLE JAMES A
IPC: G06F9/38
Filed: 1993-12-27
Granted: 1999-08-12
Abstract: A method and system for permitting single cycle instruction dispatch in a superscalar processor system which dispatches multiple instructions simultaneously to a group of execution units (24) for execution and placement of results thereof within specified general purpose registers (62). Each instruction generally includes at least one source operand and one destination operand. A plurality of intermediate storage buffers (60) are provided and each time an instruction is dispatched to an available execution unit (24), a particular one of the intermediate storage buffers (60) is assigned to any destination operand within the dispatched instruction, permitting the instruction to be dispatched within a single cycle by eliminating any requirement for determining and selecting the specified general purpose register (62) or a designated alternate general purpose register (62). <IMAGE>
Patent DE-69325961-D1 (DE)
Inventor: CHATELIN ROGER
IPC: C08K5/13
Filed: 1993-09-30
Granted: 1999-09-16
Abstract: Use, in a plastic, of vanillin or of one of its derivatives, preferably ortho-vanillin or syringaldehyde to impart an ultraviolet radiation barrier effect to the said plastic, optionally in combination with an additive, for example a dye or an inorganic additive capable of modifying the UV spectrum of vanillin or of its derivative by shifting the absorption break region into the visible. Where a plastic film for packaging foodstuff products is involved, the additive is preferably an alimentary-grade dye, for example an E 110 or E 102 or E 104 yellow in a proportion of 0.01 to 0.1 % by weight. It may also involve a colloidal silica whose elementary particles can cluster in the said plastic film into agglomerates less than one micrometre in size.
Patent DE-69332413-D1 (DE)
Inventor: GRIMM A
IPC: A61K35/14
Filed: 1993-04-13
Granted: 2002-11-21
Abstract: The properties of two recombinant human IL-2 analogues with mutations at Arginine 38 (->Alanine) and Phenylalanine 42 (->Lysine) were analyzed and compared to those of native IL-2. These analogues were found to maintain their ability to bind to the intermediate IL-2 receptor, p75, while binding only minimally to the high affinity p55+p75 receptor complex. The analogues also maintained the ability to stimulate peripheral blood mononuclear cells to generate lymphokine activated killing (LAK). However, IL-1 beta  and TNF- alpha  secretion were significantly reduced in response to the analogues, as compared to the native IL-2 molecule. These analogues are therefore potentially valuable low-toxicity alternatives to IL-2 in human immunotherapy and adoptive immunotherapy treatment strategies.
Patent DE-69409110-D1 (DE)
Inventor: HIISMAEKI PEKKA
IPC: G21C5/00
Filed: 1994-05-24
Granted: 1998-04-23
Abstract: PCT No. PCT/FI94/00206 Sec. 371 Date Jun. 10, 1996 Sec. 102(e) Date Jun. 10, 1996 PCT Filed May 24, 1994 PCT Pub. No. WO94/29881 PCT Pub. Date Dec. 22, 1994The invention concerns a moderator material used for moderation of high-velocity neutrons, in particular of fission neutrons, to epithermal neutrons. The principal components of the moderator material are aluminum fluoride and aluminum metal, which have been formed into a dense composite substantially free of pores, wherein the material contains 20 to 50%-vol. of aluminum metal and 80 to 50%-vol. of aluminum fluoride. Further, the use of the moderator material in accordance with the invention in neutron capture therapy of cancer tumours is described, such as in boron neutron capture therapy (BNCT).
Patent DE-69409125-D1 (DE)
Inventor: LYONS DONALD
IPC: C09J151/00
Filed: 1994-12-06
Granted: 1998-04-23
Abstract: Blends of chloroprene homopolymers or copolymers with chloroprene/acrylate or chloroprene/methacrylate graft copolymers provide compositions especially useful as components of latex adhesive formulations.
Patent DE-69413599-D1 (DE)
Inventor: GILLIARD PIERRE
IPC: B29C48/09
Filed: 1994-05-25
Granted: 1998-11-05
Abstract: The tube exhibits moduli (moduluses) in tension, measured at 23@C, in the longitudinal direction and in the transverse direction, of at least 3000 MPa and an external diameter/thickness ratio lying between 10 and 100. This tube is particularly suitable for producing large-diameter pipelines for transporting using gravity and distributing fluids under pressure.
Patent DE-69422662-D1 (DE)
Inventor: HANSON RONALD L
IPC: C12N1/20
Filed: 1994-06-10
Granted: 2000-02-24
Abstract: An enzymatic hydrolysis method, wherein one or more C-10 acyloxy-bearing taxanes are contacted with an enzyme or microorganism capable of hydrolyzing said acyloxy groups to hydroxyl groups. Also provided is an enzymatic esterification method, wherein one or more C-10 hydroxyl-bearing taxanes are contacted with an acylating agent and an enzyme or microorganism capable of esterifying said hydroxyl groups to form acyloxy groups. Further provided is an enzymatic hydrolysis method, wherein one or more C-13 acyloxy-bearing taxanes are contacted with an enzyme or microorganism capable of hydrolyzing said acyloxy groups to hydroxyl groups. The methods are especially useful for the preparation of compounds which may be employed as intermediates in the preparation of taxanes such as taxol.
Patent DE-69504069-D1 (DE)
Inventor: ZHENG JOE
IPC: G06K7/14
Filed: 1995-06-01
Granted: 1998-09-17
Abstract: A method and system for decoding a two-dimensional optical symbol in the spatial domain. The system determines the orientation of an imaged symbol in the spatial domain by using a template to derive a correlation coefficient between radially adjacent signals at a given angle of the template and comparing the correlation coefficients as the template is rotated with respect to the image. The angle of the highest correlation coefficient corresponds to the orientation of a set of symbol axes which include contiguous elements whose centers are collinear. The system then locates each individual information-encoded element of the symbol by using segments of the symbol defined by the axes, first adjusting for each segment the axis position and element size for subsequent determination of the location of all elements for decoding. The system is disclosed as applied to a symbol constructed as a matrix of hexagonal information-encoding elements arranged in a square, with, at its center, an acquisition target consisting of six concentric rings of alternating light and dark reflectivity. Also disclosed is a method for locating an acquisition target consisting of a plurality of concentric rings of alternating levels of reflectivity (bulls-eye pattern) in two-dimensional symbologies. Such targets may be found even if they vary in size and tilt angle with respect to an imaging camera. Symmetry characteristics of the targets are used to locate the targets independent of the threshold level selected for determining transitions between rings of different reflectivity. <IMAGE>
Patent DE-69509764-D1 (DE)
Inventor: ROSSI TINO
IPC: C07F7/18
Filed: 1995-03-23
Granted: 1999-06-24
Abstract: PCT No. PCT/EP95/01114 Sec. 371 Date Jan. 3, 1997 Sec. 102(e) Date Jan. 3, 1997 PCT Filed Mar. 23, 1995 PCT Pub. No. WO95/26333 PCT Pub. Date Oct. 5, 19951. A process for the preparation of compounds of formula (I) wherein R1 is a hydroxyl protecting group    <IMAGE>  (I)  which comprises reacting the azetidinone (II) with the homochiral (2S)-2- methoxycyclohexane (III) or the complex thereof formed with one molecule of stannic chloide.    <IMAGE>  (II)   <IMAGE>  (III)
Patent DE-69513029-D1 (DE)
Inventor: ROLANDER ULF
IPC: C25F3/08
Filed: 1995-12-05
Granted: 1999-12-02
Abstract: There is disclosed a method for edge rounding of cutting tool inserts of cemented carbide or titanium based carbonitride alloys. An electrolytic method is used with an electrolyte which provides an even removal of both binder phase and hard constituent phases. The electrolyte comprises perchloric (HC104) sulphuric (H2SO4) acid, 2-15 vol %, and mixtures thereof in methanol or other suitable organic liquid. The method is easier to control than conventional mechanical methods and is particularly useful for providing very small edge radii of about 10  mu m which cannot be made by mechanical methods.
Patent DE-69516636-D1 (DE)
Inventor: FUNTEN MARC
IPC: E04B9/16
Filed: 1995-11-07
Granted: 2000-06-08
Abstract: The structure consists of supporting rails (14P, 14S) for the ceiling panels (12), connected to a framework (22) of I-beams suspended from the main ceiling (10). The lower flanges (26) of the I-beams have cut-away sections (23) at regular intervals to receive clips (35) connecting them to the rails. Each of the rails has a thicker portion (18) along its upper edge, and each clip (35) has two downward-pointing lugs with an aperture between them shaped to receive the upper edge of a rail.
Patent DE-69528092-D1 (DE)
Inventor: FREEMAN JEFFREY W
IPC: C08F4/69
Filed: 1995-02-17
Granted: 2002-10-17
Abstract: A process is provided to stabilize and/or reactivate an olefin production catalyst system which comprises contacting an olefin production catalyst system, either before or after use, with an aromatic compound.
Patent DE-69534872-D1 (DE)
Inventor: GOLSTEIN PIERRE
IPC: A61K31/00
Filed: 1995-01-03
Granted: 2006-05-11
Abstract: CTLA-8 antigen from a primate, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding the antigen. Uses of the reagents are also provided.
Patent DE-69605677-D1 (DE)
Inventor: FOWLER H
IPC: C25D17/12
Filed: 1996-07-10
Granted: 2000-01-20
Abstract: An existing, usually used radial lead anode in an electroplating cell is machined to a specific radius. This provides a curved, machined surface for the lead anode to serve as a support structure. A thin gauge, dimensionally stable sheet anode of a multitude of side-by-side strip anodes is formed, with each strip anode being typically formed to a larger radius then the radius of the support structure. The sheet anode strips may be precurved into a series of chords. The strip anodes are flexed into place onto the surface of the lead support structure. Fastening these strips and the support structure together can be accomplished by a series of fastening means attached to the back of each strip anode, which means can project into or through holes in the lead support structure. Electrical connection can be provided, such as through the fastening means, with the lead support structure serving as a current distributor member. The lead support structure, which may be slightly soluble in cell electrolyte, is protected by the sheet anode. Moreover, the sheet anode is readily removable, such as for renovation of an active anode coating.
Patent DE-69609298-D1 (DE)
Inventor: HAEBERLI ADRIAN
IPC: B65G47/02
Filed: 1996-12-10
Granted: 2000-08-17
Abstract: A machine for the formation of tablets of cosmetic product comprises feeding means (1, 12) of a cosmetic product in powder to a movable conveyor belt (2), so as to form a layer of cosmetic product (5) that is not levelled, levelling means (4) of the layer of cosmetic product (5) that is not levelled, placed downstream from said feeding means (1, 12) of the cosmetic product, to form a layer of levelled cosmetic product (5), and portioning and compression means (7) of the layer of cosmetic product for the formation of tablets of cosmetic product (35). The levelling means (4) comprise a plurality of thread-like elements (28), preferably wires made of steel, placed in circumferential succession and extending in a direction transversal to the direction of translation of said conveyor belt (2); the thread-like elements (28) are placed in rotation round a common axis of rotation, transversal to the direction of translation of the conveyor belt (2), in a direction such as to oppose the movement of translation of the layer of cosmetic product (5) that is not levelled on the conveyor belt. <IMAGE>
Patent DE-69617937-D1 (DE)
Inventor: ZIEGLER KARL
IPC: B23B31/11
Filed: 1996-04-23
Granted: 2002-01-24
Abstract: PCT No. PCT/AU96/00234 Sec. 371 Date Oct. 23, 1997 Sec. 102(e) Date Oct. 23, 1997 PCT Filed Apr. 23, 1996 PCT Pub. No. WO96/33833 PCT Pub. Date Oct. 31, 1996A rotatable machine tool such as a precision boring tool has a head (2) that is detachably mounted on a shank type driving element (3). The head carries a removable cutting tip (9) and includes a bearing point (8) that wedgingly seats within a transverse slideway (7) in driving element (3). A slide (11), which is mounted in through bore (20) in head (2), has a male member (10) attached thereto which passes through a slot (24) extending between the bore (20) and an end face (19) of the head (2). Male member (10) is received within a bore (12) in driving element (3). A clamping screw (13) in drive element (3) interacts with male member (10) to cam it inwardly thereby clamping head (2) in position on drive element (3). The head (2) is transversely adjustable within slideway (7) by loosening screw (13) and adjusting opposed screws (32, 33) in head (2) which act on male member (10). The invention provides a driving interconnection between the drive element (3) and head (2) that is highly rigid, provides for easy diameter-wise adjustment of the head and is readily able to be assembled and disassembled for exchange of one head for another.
Patent DE-69635272-D1 (DE)
Inventor: DEIGIN VLADISLAV ISAKOVICH
IPC: C07K5/10
Filed: 1996-02-28
Granted: 2006-02-23
Abstract: The invention relates to medicine, specifically, to methods of obtaining biologically active substances with immuno-regulating properties, and can be used in medicine and veterinary science and in experimental biochemistry. The fundamental problem addressed by the invention is that of producing a noval synthetic biologically active peptide with immuno-regulating properties and of the formula: X-Glu-Trp-Y, in which X is H or Gly, Ala, Leu, Ile, Val, NVal, Pro, Tyr, Phe, Trp, D-Ala, D-Leu, D-Ile, D-Val, D-NVal, D-Pro, D-Tyr, D-Phe, D-Trp, y-aminobutyric acid,  zeta  -aminocapronic acid; Y is Gla, Ala, Leu, Ile, Val, NVal, Pro, Tyr, Phe, Trp, D-Ala, D-Leu, D-Ile, D-Val, D-NVal, D-Pro, D-Tyr, D-Phe, D-Trp, y-aminobutyric acid zeta  - aminocapronic acid, -OH, mono- or di-substituted amide (C1 -C3). Peptide synthesis takes place in a solution by successive growth of a chain from the C termination of the molecules, using a strategy of maximum blocking of functional groups, starting from amino acid alkyl ether, using the method of activating the ethers and the method of mixed anhydrides using tributyloxicarbonyl amino acid.
Patent DE-69635726-D1 (DE)
Inventor: LINDSAY JOHN
IPC: G01N27/416
Filed: 1996-11-06
Granted: 2006-04-06
Abstract: The presence of a serviceable electrochemical gas sensor (1) in gas detecting apparatus is determined on the basis of the noise in the output of a sensor amplifier. A microcomputer (22) calculates mean, rms or variance values for the noise in the output of the amplifier (20) for successive periods. Each of these values is compared with the threshold and if it falls below the threshold, counter is incremented. When the counter reaches a target value, it is determined fault condition as arisen and an alarm (23) is operated. <IMAGE>
Patent DE-69705114-D1 (DE)
Inventor: BOYD E
IPC: A61P9/00
Filed: 1997-03-26
Granted: 2001-07-12
Abstract: The 4-[(thien-2-yl)methyl]-imidazoles of the formulae:   <IMAGE>   wherein R is hydrogen or methyl, X is hydrogen, C1-4alkyl, bromine or chlorine, and Y is hydrogen, C1-4alkyl, bromine or chlorine; with the proviso that X and Y are not both simultaneously hydrogen. have exceptional analgesic activity.
Patent DE-69706306-D1 (DE)
Inventor: ROHRBACH P
IPC: B01D47/02
Filed: 1997-06-19
Granted: 2001-09-27
Abstract: A unique filtration method and device (10) which continuously removes several gas phase contaminants from an air stream through the use of partially hollow wicking fibers (20) impregnated with a selected liquid which can capture the gas phase contaminants. The wicking fibers (20) are generally disposed parallel and are formed into a filter element (12) which extends from the air stream to be cleaned into another air stream which can strip and carry away the unwanted gas phase contaminants. The gas phase contaminants are conveyed to the stripping air stream by a concentration factor induced molecular migration. The air stream to be cleaned is directed through a compartment (16) across which the filter element (12) extends so the complete air flow is through filter element (12). Filter element (12) also extends into another compartment (18) through which the stripping air stream flows. The wicking fibers (20) include internal longitudinal cavities (22) each with a relatively small longitudinal extending opening (24). The wicking fibers (20) are filled with the selected contaminant removing liquid through capillary action by which the individual wicking fibers (20) rapidly draw the selected liquid, with which they come into contact, through the internal cavities (22). The absorption liquid remains within the wicking fiber cavities (22) and generally does not enter the space between the wicking fibers yet through the longitudinal openings (24) the liquid is in full communication with the air stream flowing past the fibers (20).
Patent DE-69716250-D1 (DE)
Inventor: MENDOLIA S
IPC: A61K8/88
Filed: 1997-03-28
Granted: 2002-11-14
Abstract: A base composition and corresponding cosmetic composition are disclosed which can be formed as solids (for example, gels or sticks) and which comprise a solvent which includes a silicone fluid (for example, a silicone oil such as cyclomethicone) and a thickening agent formed from a wax and a polyamide gellant wherein at least one of the wax and polyamide includes silicon-containing moieties (for example, siloxane groups to have a siloxane diamide wax to enhance compatibility of the silicone fluid in the composition). A cosmetically active material, such as a deodorant or antiperspirant active material, is included in the composition to form a solid cosmetic product (antiperspirant or deodorant product), which can be a clear product. Compositions of the present invention can be made with increased amounts of silicone fluid and with improved aesthetic such as decreased tack.
Patent DE-69716457-D1 (DE)
Inventor: JOHANSON JERRY R
IPC: B65D88/66
Filed: 1997-11-03
Granted: 2002-11-21
Abstract: An improvement to a hopper to promote the flow of solid particulate material includes mounting one or more walls of the hopper for limited oscillatory motion in a direction parallel to the wall and perpendicular to the desired flow direction, and then providing an actuator connected to the remainder of the hopper to impart such motion to the wall. The relative motion between the moving wall and the particulate material effectively rotates the friction force to the direction of relative motion, leaving the friction in the desired flow direction approaching zero. As a result, downward flow can occur on walls that are only shallowly inclined. The improvement is applicable to hopper-like structures in railroad cars and ships, where it facilitates discharge onto moving conveyors.
Patent DE-69719996-D1 (DE)
Inventor: VAN WIJCK GERARDUS
IPC: C07D251/62
Filed: 1997-06-11
Granted: 2003-04-24
Abstract: The invention relates to a method for the preparation of melamine from urea via a high-pressure process in which solid melamine is obtained by transferring the melamine melt leaving the melamine reactor to a cooling vessel where the melamine melt is cooled by means of liquid ammonia. The melamine melt is cooled to a temperature of between about 50° C. and about 350° C. by means of liquid ammonia, a mixture comprising ammonia and melamine being formed, after which all or part of this mixture is transferred to an expansion vessel, the composition being contacted with ammonia for about one minute to about five hours, following which solid melamine is liberated from the composition.