baber/WOPTO huggingface dataset:
Patent DO-P2004000867-A (DO)
Title: Recuperacion de metales preciosos utilizando un lixiviante de tiocianato
Inventor: WAN RONG YU
Filed: 2004-03-26
Abstract: Un material mineral que contiene metales preciosos es sometido a una lixiviacion acida con tiocianato para disolver los metales preciosos en la forma de complejos de metales preciosos-tiocianato. La alimentacion de solución de lixiviacion de tiocianato puede incluir una relacion molar alta de hierro ferrico a tiocianato. Los metales preciosos se pueden separar de la solución de lixiviacion de tiocianato prenada, tal como por transferencia de metales preciosos de los complejos de metales preciosos-tiocianato a complejos de metales preciosos-cianuro y despues cargar los complejos de metales preciosos-cianuro sobre un material adsorbente. El cianuro restante en la solucion de lixiviacion de tiocianato puede ser convertido en tiocianato para una lixiviacion adicional de metales preciosos.
Patent DO-P2009000172-A (DO)
Title: Metodo de extraccion y aparato para el dispositivo de prueba del flujo corporal de alta sensibilidad.
Inventor: GOULD MARTIN
IPC: B01L99/00
Filed: 2009-07-08
Abstract: Un método de extracción y aparatos se proporciona para la obtención rápida, segura y altamente sensible de cualquier prueba de una gran variedad de fluidos corporales incluyendo la saliva, sangre, orina u otros fluidos de abuso de drogas u otros analitos. El aparato incluye un tubo de extracción latchable para la obtención de muestras de fluidos corporales de un tema que esta adaptado para aprovechar al máximo la parte de la muestra de fluido corporal que ira en un frasco con un graduado la solución tampón, y un dispositivo de prueba que la muestra se ha recibido y tiras de prueba en la que se pueden insertar para determinar los niveles de abuso de drogas u otros analito en la muestra. En uno de los métodos de la invención, se imparte energía a la muestra y la solución tampón, por ejemplo, agitación, y esto facilita la reducción de la viscosidad de la muestra, por ejemplo la promoción de la ruptura de mucinas cuando la muestra de saliva.
Patent DO-P2009000177-A (DO)
Title: Uso de derivados de acido de piranona sustituidos para el tratamiento del sindrome metabolico
Inventor: URMANN MATTHIAS
Filed: 2009-07-13
Abstract: La invención se refiere al uso de derivados de acido de piranona sustituidos y de sus sales fisiológicamente aceptables para producir medicamentos para tratar el síndrome metabólico. Se describe el uso de compuestos de la formula I En la cual los radicales tienen los significados dados, así como sus sales fisiológicamente aceptables para producir un medicamento para tratar el síndrome metabólica.
Patent DO-P2013000084-A (DO)
Title: Peptidomimeticos de smac utiles como inhibidores de proteinas de apoptosis (iap)
Inventor: CHAREST MARK G
IPC: A61K31/427
Filed: 2013-04-16
Abstract: La presente invención se refiere a un compuesto de la fórmula (I); o sales farmacéuticamente aceptables del mismo, y al uso de estos compuestos para el tratamiento de enfermedades proliferativas, tales como cáncer, en mamíferos.
Patent DO-P2014000135-A (DO)
Title: Compuestos novedosos de benzopirano, composiciones y usos de los mismos
Inventor: KUSHNER PETER J
IPC: C07D311/00
Filed: 2014-06-16
Abstract: Se proveen compuestos de benzopirano con fuerte actividad anti-estrogénica y en esencia ninguna actividad estrogénica, que son OP-1038, que es 3-(4-hidroxifenil)-4-metil-2-(4-{2-[(3R)-3-metil-pirrolidin-1-il]etoxi}fenil)-2H-cromen-7-ol, y OP-1074, que es (2S)-3-(4-hidroxifenil)-4-metil-2-(4-{2-[(3R)-3-metilpirrolidin-1-il]etoxi}fenil)-2H-cromen-7-ol. OP-1074 es un anti-estrógeno puro cuando es probado en el modo agonista y un anti-estrógeno completo cuando se prueba en el modo antagonista. Estos compuestos son útiles para la fabricación de medicamentos útiles para el tratamiento o prevención de una variedad de condiciones que son modulados a través del receptor de estrógeno en mamíferos incluyendo humanos.
Patent DO-P2020000003-A (DO)
Title: Maquina termica canfigurada para realizar ciclos de calor y procedimiento para realizar ciclos de calor medio de dicha maquina termica
Inventor: SERGIO OLIVOTTI
IPC: F01K13/00
Filed: 2020-01-03
Abstract: Una máquina térmica (121) para realizar un ciclo de calor, funcionando la máquina térmica con un fluido térmico y comprendiendo una unidad de accionamiento (1) provista de un primer rotor (4) y un segundo rotor (5), teniendo cada uno tres pistones (7a, 7b, 7c; 9a, 9b, 9c) que se pueden deslizar en una cámara anular (12), en la que los pistones delimitan seis cámaras de volumen variable (13, 13, 13'; 14, 14, 14). La unidad de accionamiento comprende una transmisión configurada para convertir el movimiento rotatorio con las correspondientes velocidades angulares periódicamente variables primera y segunda (¿1, ¿2) de dicho primer y segundo rotor (4, 5), desplazados entre sí, en un movimiento rotatorio a una constante velocidad angular. La máquina térmica comprende además un tanque de compensación (44), configurado para acumular el fluido térmico comprimido desde la unidad de accionamiento, un regenerador (42) configurado para precalentar el fluido térmico, un calentador (41) configurado para supercalentar el fluido térmico que circula en la serpentina, un quemador (40), configurado para suministrar la energía térmica necesaria al calentador (41); en el que el regenerador (42), en comunicación fluida con la unidad de accionamiento (1), está configurado además para adquirir calor de energía del fluido térmico agotado y usarlo para precalentar el fluido térmico para su envío al calentador (41). La invención se refiere además a un procedimiento para realizar un ciclo de calor por medio de dicha máquina térmica.
Patent DO-P2023000107-A (DO)
Title: Compuesto de heteroarilcarboxamida
Inventor: HIDEYUKI WATANABE
IPC: A61K31/454
Filed: 2023-05-29
Abstract: Se proporciona un compuesto útil como principio activo de una composición farmacéutica para el tratamiento del cáncer relacionado con la activación de células inmunitarias o el cáncer resistente a la terapia con anticuerpo anti-PD-1/anticuerpo anti-PD-L1. 	Los presentes inventores han realizado estudios sobre un compuesto útil como principio activo de una composición farmacéutica para el tratamiento del cáncer relacionado con la activación de células inmunitarias o cáncer resistente a la terapia con anticuerpo anti-PD-1/anticuerpo anti-PD-L1, y han confirmado que un compuesto de heteroarilcarboxamida tiene un efecto inhibidor ¿ de DGK (DGKzeta), lo que conduce a la finalización de la presente invención. El compuesto de heteroarilcarboxamida de la presente invención tiene un efecto inhibidor ¿ de DGK y puede usarse como un agente terapéutico para el tratamiento de cáncer relacionado con la activación de células inmunitarias o cáncer resistente a la terapia con anticuerpo anti-PD-1/anticuerpo anti-PD-L1.
Patent EC-SP11011238-A (EC)
Title: METODO PARA MULTIPLICAR TEJIDO CELULAR DE Jatropha curcas
Inventor: ATEHORTUA GARCES LUCIA
IPC: C12N5/02
Filed: 2011-07-26
Abstract: El método de la presente invención comprende: Obtener un explante de la semillas de Jatropha curcas; Poner el explante derivado de la semilla de Jatropha curcas en un medio de cultivo; Romper las uniones intercelulares del tejido de los explantes, los que generan células individuales; Incubar por un tiempo determinado el medio de cultivo con las células individuales generadas, las cuales se multiplican; y, Extraer aceite de las células que se multiplicaron a partir de las células individuales generadas de los explantes derivados de la semilla de Jatropha curcas.
Patent EC-SP14013224-A (EC)
Title: Pirimidinas anilladas sustituidas y uso de las mismas
Inventor: Hübsch Walter
IPC: C07D519/00
Filed: 2014-02-28
Abstract: La presente solicitud se refiere a pirimidinas anilladas sustituidas novedosas, a procedimientos de producción de las mismas, al uso de las mismas solas o en combinaciones para el tratamiento y/o la prevención de enfermedades y al uso de las mismas para la producción de medicamentos para el tratamiento y/o la prevención de enfermedades, en particular para el tratamiento y/o la prevención de enfermedades cardiovasculares.
Patent EE-200100507-A (EE)
Inventor: AHOTUPA MARKKU
IPC: A23L1/30
Filed: 2000-03-09
Abstract: This invention relates to methods for prevention of cancers, certain non-cancer, hormone dependent diseases and/or cardiovascular diseases in a person, based on administering of hydroxymatairesinol to said person. The invention also concerns a method for increasing the level of enterolactone or another metabolite of hydroxymatairesinol in a person's serum thereby causing prevention of a cancer or a certain non-cancer, hormone dependent disease in a person, based on administering of hydroxymatairesinol to said person. Furthermore, this invention relates to pharmaceutical preparations, food additives and food products comprising hydroxymatairesinol.
Patent GB-189317514-A (GB)
Title: Improved Means of Protecting Timber Structures.
Inventor: SMITH WILLIAM
Filed: 1893-09-18
Granted: 1894-01-20
Abstract: 17,514. Smith, W. Sept. 18. Buildings, subaqueous.-Timber and timber structures are protected from sea-worms, damp, &c., by a covering of canvas, felt, cloth, or paper, soaked in an antiseptic asphalt composition, or soaked first in an antiseptic composition and then in asphalt.
Patent GB-189706361-A (GB)
Title: Improvements in Gill Boxes for Preparing Wool and other Fibre.
Inventor: THORNTON JOHN TYNE
Filed: 1897-03-11
Granted: 1898-02-12
Abstract: 6361. Thornton, J. T., and Kilner, A. J. March 11. Gill boxes or frames.-In place of the usual gill fallers a spiked roller A is used, the pins or gills a being set into the roller in an inclined position as shown. The roller is rotated in the same direction as that in which the fibre travels, and is cleaned by a rotary brush D.
Patent GB-189707111-A (GB)
Title: Improvements in Apparatus for Screening, Sorting, and Picking Coal.
Inventor: BUTLER WILLIAM FREDERIC
Filed: 1897-03-18
Granted: 1898-02-05
Abstract: 7111. Butler, W. F. March 18. Screening and sorting coal. -The trucks, corves, or tubs A which convey the coal from the pit's mouth deposit it on the inclined screens B, down which it passes by gravity The large coal is carried by travelling or picking belts C to the wagons C'. The nuts and dust which pass the screens fall through the hoppers D, which may have false screen bars, on to the travelling bands E, which convey them to the elevator F. The dust is separated from the nuts at the screen G and is discharged at H. The nuts pass to a three-way hopper, from which they may be conveyed by shoots K to mix with the large coal, or may be separately discharged, as desired. The belts C are built up of metal plates 0, Fig. 6, running on flanged hexagonal or other open drums R. The plate 0 may be perforated so as to further screen the coal.
Patent GB-189708231-A (GB)
Title: Improvements in Storage Batteries.
Inventor: REDFERN GEORGE FREDERICK
Filed: 1897-03-30
Granted: 1898-03-19
Abstract: 8231. Redfern, G. F., [Riordon, C.]. March 30. Secondary batteries.-Fig. 1 shows two cells, and Fig. 2 a single electrode, parts being broken away. Each electrode is made up by helically winding a rectangular lead strip D round a central grooved support A, and packing in the spaces between the coils with oxide D<1>. From about the centre of the helix a conducting-strip E is led to one of the binding-p )sts I, J, which have spherical heads ; the posts in adjacent cells are connected by grooved plates L and bolts M. The supports A are held in insulating-plates F, K, of which K forms a cover for the cell. The upper ends of the supports A are notched, and in the notches are held elastic bands H, which are attached at their lower ends to pins h, and serve both to hold the oxide in place and as separators.
Patent GB-189714729-A (GB)
Title: Improved Apparatus for Delivering Cigars into Boxes.
Inventor: WITT PETER MARTIN
Filed: 1897-06-17
Granted: 1897-07-31
Abstract: 14,729. Witt, P. M., and Eggers, J. H. June 17. Packing cigars.-The machine transfers cigars from the pressing - boxes into the labelled boxes ready for sale. The pressing-box is inverted, a loose lid being provided to it, and is held at the ends by the ends of the sliding pieces g, g<1> which are pushed down, extending the springs i, i<1>, until the loose lid rests on the table T. The framework is telescopic, so that, by means of the handwheel e, the fingers g, g<1> can be adjusted to fit boxes of various sizes. On releasing the spring catches h, h<1> the pressing-box is lifted and removed, the labelled box being then brought down upon the cigars which remain upon the table T. The height to which the box is raised is determined by the position of the setscrews or stops k, k<1> in the slots l, l<1>. In a modification, both ends of the casing are arranged to slide, each bearing a rack which engages with a pinion turned by the hand-wheel.
Patent GB-189714783-A (GB)
Title: Tobacco Pipe, Cigar, and Cigarette Holder.
Inventor: SIGURDSON JOHN
Filed: 1897-06-18
Granted: 1898-06-04
Abstract: 14,783. Sigurdson, J. June 18. Tobacco pipes and cigar and cigarette holders.- The stem of the pipe is telescopic, consisting of tubes 26, 27, 28 sliding one within the other. The mouthpiece 31 is fixed into the outer end of the inner tube 28, the inner end of which is closed by the piece 24, leaving a space or chamber for saliva. To the end of the piece 24 is connected one end of a t u b e 22 which winds round the inner bowl 4 and is connected to a nozzle 20 of a nicotine chamber 8. The inner bowl 4 rotates within the outer bowl 1, which is connected to the outer tube 26 by arms 30. A screw valve 15, 16 is provided for opening or closing the passage 6 to the bowl. A removable cigar or cigarette holder 18 passes through an opening in the outer bowl to the chamber 8. This cigar &c. holder is removed when the stem is to be drawn out and the inner bowl rotated. When the cigar &c. holder is used the passage 6 is closed by the valve. Cotton or other absorbent may be placed in the chambers.
Patent GB-189719579-A (GB)
Title: Improvements in Auto-motor Carriages or Vehicles.
Inventor: BREWER WILLIAM JOHN
Filed: 1897-08-25
Granted: 1898-11-25
Abstract: 19,579. Brewer, W. J., and Cooper, J. E. Aug. 25. Electric locomotives and motor vehicles. - The vehicle frame is supported on the main axles c, Fig. 8, through the medium of antifriction wheels d running loose on axles a. The axles a and c run in axle-boxes a', c<1> guided by horn-plates b, and are mutually constrained by the guide-boxes f, as shown in side elevation in Fig. 4. The collars e are divided and, in the case of electrically-propelled vehicles, may enclose insulating-material. The electric motor in such cases may be arranged and supported upon the axle a, as shown in Fig. 8. In a modification, two horn-plates may be provided on each side of the vehicle and the central portion of the axle a may be removably attached by couplings to short axles at each end, or may be entirely dispensed with. In other cases additional antifriction wheels may be provided for sustaining the lateral pressures on the axles. The fore-carriage may also be constructed with antifriction wheels. It is operated and controlled by a pinion gearing with a toothed segment fixed to the main frau.e. In order to adapt the vehicle for running on rails, guard lips or rollers may be provided, which are capable of being raised or depressed as required. The former, shown in Fig. 12, is given by way of example. The guard lip m is kept close to the wheel tread by means of a roller m<2> engaging with an undercut recess m<1> at the back of the wheel. In other examples in the Specification, vertical and horizontal guard-wheels are shown.
Patent GB-189727806-A (GB)
Title: Improvements in Electrical Switches.
Inventor: WATSON ALFRED
Filed: 1897-11-26
Granted: 1898-10-15
Abstract: 27,806. Watson, A. Nov. 26. Switches.-Figs. 1 and 2 show a single - pole switch. The contact-arm d, which may be formed of a single strip of metal bent in the middle, has its free ends bent inwards and normally slightly apart. When the arm is forced down between the fixed contacts or terminals b, c, these ends are forced together and give a good connection. The arm d, and also the handle g, are pivoted on a cross-pin e'. The handle is fitted with a shoe or collar g<2>, which gives a positive movement to the contact-bar, a spring f giving a quick break. For double-pole switches, two contact-bars are mounted on a spindle which is operated by a single handle.
Patent GB-189807683-A (GB)
Title: Improvements in Transport Wagons or Trucks for Slag.
Inventor: BOCHKOLTZ CONSTANTIN
Filed: 1898-03-30
Granted: 1898-06-04
Abstract: 7683. Bochkoltz, C. March 30. Axle-trucks; tip-wagons.-To enable tip-wagons to be coupled to ordinary trains, the axle-truck a, Fig. 1, is provided with a transverse plate b, which carries the buffers d at the required height. The wagon can be made to tip on either side, and the platform is retained in horizontal position by a hinged prop c, Fig. 3, which is locked in upright position by a hook D having an engaging tooth q.
Patent GB-189810287-A (GB)
Title: Improvements in Fenders, Fender Curbs, Fire Dogs, Ash Pans, Fire Screens, Coal Boxes, Coal Box Stands and Fire Iron Companions, and in the Mode of Manufacturing the same.
Inventor: ADDICOTT BENJAMIN
Filed: 1898-05-05
Granted: 1898-08-20
Abstract: 10,287. Addicott, B., and Holland, G., [trading as Addicott & Holland]. May 5. Fenders; fire-dogs; ashpans.-These articles are made from steel, wrought-iron, &c. bars M, M', M', cut to length and placed in chill moulds and connected together by pouring in molten metal, which forms cast-metal junctions and ornaments C. Suitably-formed ornamental rods may be chilled to the bars M and to one another in the same manner. For instance, tubes T are laid in the mould and connected to the parts E, C, A with hole a<1>. The ornaments or parts B may have screws dropped into holes a' and secured by nuts. The knobs K are cast in parts C, E. Fire-iron stands for suspending fire-irons are similarly made.
Patent GB-189810454-A (GB)
Title: Improvements in Railway Switches and Means for Operating same.
Inventor: KELLY BENGEL JOY
Filed: 1898-05-07
Granted: 1899-05-06
Abstract: 10,454. Kelly, B. J. May 7. Points and switches operated from railway vehicles &c. The pivoted rails 5 connected to a plate 8 are thrown to one side or the other by the arm 12 of a three-armed lever which is connected by cords &c. 29, 31, 40 to levers 23, 32, 41 placed between the rails of the main line and sidings. The ends of these levers project through the sides of open-topped boxes 26, 36, 45 into which an arm can be lowered from the vehicle or locomotive so as to operate the points. On the plate 8 connecting the tongues are mounted two bolts 21 which are operated by projections on the arm 12 of the three-armed lever acting through bell cranks 17. Suitable means, such as are indicated at 69, can be used for operating the points by hand. The appliance on the vehicles &c. for knocking over the levers 23, 32, 41 is shown in Fig. 3. It consists of a frame 53, pivoted at 50, which is normally lifted by the counterweight 65, but can be lowered by the handle 62 and locked in that position by a bolt 58. This bolt is connected by a bell crank 57 to a second pivoted frame 55, so that it is liberated when this frame strikes tops 46, 47, or 48 in the roadway.
Patent GB-189812385-A (GB)
Title: Improvements in and relating to Window Sash Fasteners and the like.
Inventor: TOMKINSON GEORGE
Filed: 1898-06-02
Granted: 1898-07-23
Abstract: 12,385. Tomkinson, G. June 2. Sash and like fastenings.-A leaf spring A is fixed at one end to the meeting-rail B of the lower sash, its free end having a pin C which can be depressed into a hole D. On turning the arm of an ordinary sash fastener into the locking position, the spring is first depressed, but automatically rises and locks the arm in this position till the spring is again depressed from the inside. The spring may be applied to any suitable fastening for windows, doors, fanlights, &c.
Patent GB-189813303-A (GB)
Title: An Improved Sight Payment Cash Receiver and Indicator for Counter use.
Inventor: PARER FRANCIS
Filed: 1898-06-14
Granted: 1898-08-06
Abstract: 13,303. Parer, F. June 14. Tills. - Consists of an exhibition chamber A, a shoot B therefrom, a locked drawer C which receives the gross payments, and a free drawer D for affording change. A vertical rod E supported by a spring is pulled down by a bevel F on the drawer, or can be operated by hand so as to sound a gong by the hammer g. Three hinged shelves H, H<1>, H<2> in the exhibition chamber are linked to this rod in such a way that, when the extreme ones are raised, the middle one is lowered, and vice versÔ.
Patent GB-189813745-A (GB)
Title: Improvements in Wheels and Pullies.
Inventor: IVES WILLIAM
Filed: 1898-06-21
Granted: 1899-06-17
Abstract: 13,745. Ives, W. June 21. Hubs.-Consists of an elastic hub or boss for wheels for cycles &c. Inflated tubes or other cushion tubes or rings e, e', enclosed in a casing b, b<1>, b<2>, forming the part of the hub to which the spokes are fixed, are passed alternately over and under cross-bars a<1> secured in the sides of the other part a of the hub. Instead of being side by side, the tubes may be one outside the other, and simply bear against the cross-bars which are placed between them. In another arrangement, the rings b<1>, b<2> are replaced by series of cross-bars. The two parts of the hub may be coupled by jointed links. The sides b may be bolted to the rings b<1>, b<2>, or they may be sprung into grooves therein, or secured by screw threads or by lugs and recesses.
Patent GB-189814294-A (GB)
Title: Improvement in Regulation of Rotary Transformer Direct Current Electromotive Force.
Inventor: LAMME BENJAMIN GARVER
Filed: 1898-06-28
Granted: 1899-04-29
Abstract: 14,294. Lamme, B. G. Feb. 10, [date claimed under Sec. 103 of Patents &c. Act, A.D. 1883]. Distributing; regulating; transformers; converting alternating and direct currents.-Relates to means for regulating the electromotive force of direct currents from rotary transformers or converters supplied with alternating current. In the arrangement shown in Fig. 1, the generator 1 supplies two-phase currents to a stationary transformer 2, 3, the secondary of which is divided into sections which may be connected as desired, through the switches 19, 20, with the rotary converter 14. A rheostat 16 is included in the field 15. The regulation of the electromotive force impressed on the direct-current circuit is obtained by varying the number of sections of the stationary transformer in the circuit and by varying the resistance in the field. Choking coils 17, 18 are included in the transformer circuit, or a separate coil may be included in each of the leads 6 ... 13.
Patent GB-189821260-A (GB)
Title: Improvements in Change Box Mechanism of Looms for Weaving.
Inventor: HATTERSLEY RICHARD LONGDEN
Filed: 1898-10-10
Granted: 1899-08-12
Abstract: 21,260. Hattersley, R. L., and Jackson, S. Oct. 10. Loom change-box motions.-Consists of additions to the mechanism described in Specification No. 18,267, A.D. 1890, for the purpose of reversing the pattern when required. Two sets of feelers or indicating - levers 16 are mounted loosely on a stud 20, and are formed with slots 21 to receive sliding-blocks connected by rods 29 to levers 30, 34, which are operated by rods 35, 36 and levers 37, 38 from the pattern surface 39. The sliding blocks carry projecting pins for operating the intermediate levers 54, 55 of the box motion. The levers 30, 34 are connected also by rods 50, 53 to the operating-catches 40, 41 and 51, 52 of the cylinders 7, 8 respectively, the catches of each cylinder being connected together at the top by a rod 46 and spring 47. The shifting of the sliding blocks in their slots reverses the action of the feelers on the box motion, and the shifting of the catches reverses the cylinders 7, 8, or brings them to rest.