baber/WOPTO huggingface dataset:
Patent NO-180750-B (NO)
Inventor: BELL ANDREW SIMON
IPC: A61P27/06
Filed: 1992-07-08
Abstract: Compounds of formula: <CHEM>  and pharmaceutically acceptable salts thereof,  wherein R<1> is H; C1-C3 alkyl optionally substituted with one or more fluoro substituents; or C3-C5 cycloalkyl; R<2> is H, or C1-C6 alkyl optionally susbtituted with one or more fluoro subtituents or with C3-C6 cycloalkyl; R<3> is C1-C6 alkyl optionally substituted with one or more fluoro substituents or with C3-C6 cycloalkyl; C3-C5 cycloalkyl; C3-C6 alkenyl; or C3-C6 alkynyl; R<4> is C1-C4 alkyl optionally substituted with OH, NR<5>R<6>, CN, CONR<5>R<6> or CO2R<7>; C2-C4 alkenyl optionally substituted with CN, CONR<5>R<6> or CO2R<7>; C2-C4 alkanoyl optionally substituted with NR<5>R<6>; hydroxy C2-C4 alkyl optionally susbtituted with NR<5>R<6>; (C2-C3 alkoxy)C1-C2 alkyl optionally substituted with OH or NR<5>R<6>; CONR<5>R<6>; CO2R<7>; halo; NR<5>R<6>; NHSO2NR<5>R<6>; NHSO2R<8>; or phenyl or heterocyclyl either of which is optionally substituted with methyl; R<5> and R<6> are each independently H or C1-C4 alkyl, or together with the nitrogen atom to which they are attached from a pyrrolidinyl, piperidino, morpholino, 4-(NR<9>)-piperazinyl or imidazoyl group wherein said group is optionally substituted with methyl or hydroxy; R<7> is H or C1-C4 alkyl; R<8> is C1-C3 alkyl optionally substituted with NR<5>R<6>; and R<9> is H; C1-C3 alkyl optionally substituted with phenyl; hydroxy C2-C3 alkyl; or C1-C4 alkanoyl; are selective cGMP PDE inhibitors useful in the treatment of cardiovascular disorders such as angina, hypertension, heart failure and atherosclerosis.
Patent SE-338012-B (SE)
Inventor: STEC F
IPC: B65D17/40
Filed: 1969-02-19
Abstract: 1,219,061. Easy opening cover for a container. CONTINENTAL CAN CO. Inc. 16 Jan., 1969 [11 March, 1968], No. 2681/69. Heading B8D. A rectangular easy opening panel 17 for a container has indentations 33 and a central depression 23 which receives the ring of a pull tab. Weakening line 21 defines the tear off panel and is spaced from a shallower line 22. A nose on the pull tab breaks the weakening line in the usual way and the tab body is secured to the panel between the depression 23 and the score line by an integral rivet 18.
Patent SE-319909-B (SE)
Inventor: FARNSWORTH R
IPC: G01S13/16
Filed: 1967-04-07
Abstract: 1,180,126. Wave-energy ranging. HUGHES AIRCRAFT CO. 3 April, 1967 [8 April, 1966], No. 15164/67. Heading H4D. In a digital target ranging system a control counter 13 and a range counter 14 are provided, a clock pulse gate 11 is terminated by the control counter when it is full, Fig. 2 (c), and the range counter is reset to zero by target returns, Fig. 2 (h), (k). In the embodiment a bi-stable circuit 19 is inhibited between the occurrence t 1  of a synchronizing signal from the pulse radar or laser transmitter and a signal corresponding to minimum range t 2 , Fig. 2 (e); a minimum and maximum range are utilized. Two modes of operation are described: in the " first-target " mode a circuit 16 is enabled from time t 0  to t 3 , Fig. 2 (f), and a gate 15, Fig. 2 (g) can pass target return signals during the period t 2 t 3 ; ,the range counter 14 counts from time t 1  until time t 3  when the first target is detected and the counter 14 is then reset to zero, Fig. 2 (h) by a pulse from a circuit 20. Counter 14 resumes a counting until counter 13 is full at time t 5  and the digital output from the complement side of each binary circuit in counter 14 represents range from the radar pulse transmission to the first target. In the " lasttarget " mode, circuit 16 is enabled in the interval t 0 t 4 , Fig. 2 (i), and gate 15 is open in the interval t 2 t 4 ; counter 14 counts from time t 1 , is reset to zero by the first target return K 1 , 2 (k), recommences counting, is reset to zero by the second target return K 2 , recommences counting and is reset to zero by the last target return k 3 , and counts until counter 13 is full. The complement outputs from counter 14 then represent the range of the last target detected.
Patent RS-51398-B (RS)
Inventor: SMRCEK BRANKO
IPC: E04B7/02
Filed: 2002-11-20
Abstract: Dvostruko prednapregnuta krovno-tavanska konstrukcija sa rešetkastom ravnom tavanicom za ekstremno velike raspone veće od 50 metara, koja sadrži tavansku rešetku (1), gornju gredu (2) i spojne štapove (3) oblika cevi koji spajaju gredu (2) sa tavanskom rešetkom (1) naznačena time, što se tavanska rešetka (1) sastoji od mnoštva malih prethodno proizvedenih delova (1.1) koji formiraju tavansku rešetku, pri čemu su tavanska rešetka (1) i gornja greda (2) prilagođene da budu prednapregnute.Prijava sadrži još 5 zavisnih patentnih zahteva.
Patent ZA-845301-B (ZA)
Title: Triazolo-pyrimidine derivatives,a process for preparing them and their therapeutic use as cardiotonics
Inventor: BARTHELEMY GERARD
IPC: C07D487/04
Filed: 1984-07-10
Abstract: This invention relates to triazolo-pyrimidine derivatives corresponding to the following formula:    <IMAGE>  I  wherein X represents a 2-pyridyl, 3-pyridyl or 4-pyridyl nucleus optionally substituted by at least one straight-chained or branched C1-4 alkoxy or alkyl or a hydroxy or cyano group, R1 represents hydrogen or a straight-chained or branched saturated or unsaturated C1-5 aliphatic group, and R2 represents a straight-chained or branched C1-4 alkyl group, and the pharmaceutically acceptable acid addition salts thereof with inorganic or organic acids. These compounds may be used in therapy, particularly on account of their cardiotonic activity.
Patent ZA-853889-B (ZA)
Title: Process of producing copper(ii)hydroxide
Inventor: PLOSS HARTMUT
IPC: C01G3/02
Filed: 1985-05-22
Abstract: Copper(II) hydroxide is produced by a reaction of copper oxychloride in an aqueous suspension with alkali hydroxide or alkaline earth metal hydroxide in the presence of a stabilizing agent and the product is separated and washed. To improve the stability of the copper hydroxide and to avoid a black coloring by copper oxide, inorganic silicon compounds which contain hydroxyl groups (SiOH) in the molecules or form such groups in an aqueous medium are added to the suspension. It is desirable to use particulate solid silicic acids or silicic acids which are soluble in water or colloidally dissolved.
Patent ZA-875489-B (ZA)
Title: Diphosphonic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing them
Inventor: BOSIES ELMAR
IPC: C07F9/6527
Filed: 1987-07-27
Abstract: The present invention produces alkyldiphosphonic acid derivative of the general formula:    <IMAGE>  (I)  wherein Het is a heteroaromatic five-membered ring containing to 3 heteroatoms which can be partly hydrogenated and optionally substituted one or more times by alkyl, alkoxy, phenyl, cyclohexyl, cyclohexylmethyl, halogen or amino, and two adjacent alkyl substituents can together also form a ring, Y is a hydrogen atom or a lower alkyl radical, X is a hydrogen atom, a hydroxyl group or an amino group optionally substituted by lower alkyl and R is a hydrogen atom or a lower alkyl radical, with the proviso that Het is not a pyrazole ring; as well as the pharmacologically acceptable salts thereof. The present invention also provides processes for the prepearation of these compounds and pharmaceutical compositions containing them useful for the treatment or prophylaxis of calcium metabolism disturbances or disease as for example osteoporosis, Bechterew's disease, bone metastases, urolithiasis, heterotropic ossifications, rheumatoid arthritis osteoarthritis or degenerative arthrosis.
Patent ZA-876081-B (ZA)
Title: Compressed air modifier
Inventor: SOLA ANTONIO
IPC: B01F23/10
Filed: 1987-08-17
Abstract: PCT No. PCT/AU87/00277 Sec. 371 Date Jun. 20, 1988 Sec. 102(e) Date Jun. 20, 1988 PCT Filed Aug. 19, 1987 PCT Pub. No. WO88/01195 PCT Pub. Date Feb. 25, 1988.An apparatus to introduce a vaporized chemical agent into a compressed air supply system comprising an air inlet (25), a chemical agent storage chamber (15), and an air/chemical agent mixing chamber (13) which includes a baffle means (14) to promote turbulence and extract liquid phase chemical droplets. There is a supply means (17) to spray a controlled quantity of the chemical agent into the mixing chamber and an outlet (20) to allow removal of extracted liquid phase chemical agent from the mixing chamber (13).
Patent ZA-904000-B (ZA)
Title: Retractile penis device
Inventor: STEER GRAHAM EMERY
IPC: A61F5/453
Filed: 1990-05-23
Abstract: A device for use by persons suffering from a retractile penis. The device includes an apertured convexly curved plate (10) with an attachment ring (20) whereby a condom-like urine channelling device (26) can have one of its ends sealingly attached to the plate (10). The plate (10) may be of a hollow construction containing a cushioning liquid or gel or may be a single wall having a foam pad backing (46).
Patent ZA-908280-B (ZA)
Title: Stabilization of isothiazolones
Inventor: LAW ANDREW BONAR
IPC: A61K8/368
Filed: 1990-10-17
Abstract: A composition comprising     (a) One or more 3-isothiazolones of the formula: <CHEM>  wherein Y is a (C1-C18)alkyl or (C3-C12), preferably (C5-C8), cycloalkyl each optionally substituted with one or more of hydroxy, halo, cyano, alkylamino, dialkylamine, arylamino, carboxy, carbalkoxy, alkoxy, aryloxy, alkylthio, haloalkoxy, cycloalkylamino, carbamoxy, or isothiazolonyl; an unsubstituted or halo-substituted (C2-C8), preferably (C2-C4) alkenyl or alkynyl; a (C7-C10)aralkyl optionally substituted with one or more of halogen, (C1-C4)alkyl or (C1-C4)alkoxy; or an aryl optionally substituted with one or more of halogen, nitro, (C1-C4)alkyl, (C1-C4)alkyl-acylamino, carb(C1-C4)alkoxy or sulfamyl; and  X and X1 are each independently hydrogen, chloro, or methyl; and (b) a metal salt comprising a copper, zinc, manganese, ferrous or ferric salt, the anion of which is an organic carboxylic acid of at least six carbon atoms, EDTA, 8-hydroxyquinolinate, gluconate, o-phenanthroline, quinolinate N,N-bis(2-hydroxy-5-sulfobenzyl) glycine, a lignosulfonate polymer, or a polyacrylate; and (c) a locus to be protected against the growth of algae, bacteria, or fungi, said locus being of:   (i) a metal working fluid (MWF) comprising at least one component selected from the group consisting of an alkanolamine, a petroleum sulfonate emulsifier, a boric acid ester or boric acid amide, a corrosion inhibitor, and a fatty acid; (ii) cooling tower water comprising corrosion inhibitors or scale inhibitors;   (iii) laundry dish water;   (iv) a cosmetic formulation;   (v) a fuel system;   (vi) an emulsion;   (vii) a solid protective or decorative film; (viii) a film-forming, substantially non-wood-penetrating, organic polymeric paint vehicle in the case where the salt is a manganese, ferrous or ferric salt   is disclosed, together with a method of stabilizing 3-isothiazolones in such loci using said metal salts.
Patent ZA-913214-B (ZA)
Title: Vaccine compositions
Inventor: PENNEY CHRISTOPHER L
IPC: A61K39/29
Filed: 1991-04-29
Abstract: Improved vaccine compositions comprising a long chain alkyl compound as an immunoadjuvant in combination with a homogeneous immunogenic polypeptide. The compositions of the invention are useful in activating the immune system to confer immunity to a host against the immunogen in a prophylactic manner.
Patent ZA-915468-B (ZA)
Title: Neuromuscular blocking agents
Inventor: HILL DEREK ANTHONY
IPC: A61K31/47
Filed: 1991-07-12
Abstract: 1R-$i(cis),1'R-$i(cis) isomer of a 2',2'-(3,11-dioxo-4,10-dioxatridecylene)-bis-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium) salt, substantially free from other geometrical and optical isomers thereof. The 1R-$i(cis),1'R-$i(cis) isomer has been found to have an advantageous combination of pharmacological properties, notably greater neuromuscular blocking potency, weaker histamine-releasing potency, and at equivalent levels of neuromuscular blockage, fewer potential adverse effects on the autonomic nervous system (sympathetic and parasympathetic blockade), in comparison with the known mixture of geometrical and optical isomers.
Patent ZA-923831-B (ZA)
Title: Drying process for tobacco material and apparatus for carrying out said process
Inventor: HIRSCH WERNER
IPC: A24B3/04
Filed: 1992-05-26
Abstract: In a drying process for improving the filling capacity of tobacco material, the cut and humidified tobacco material is conveyed in a stream of drying gas, dried within a tubular drying section and then separated from the drying gas. At a point where it is charged into the drying section, the drying gas has a temperature of at least 200 DEG C and a flow velocity of at least 30 m/sec. The flow velocity of the drying gas is reduced in the drying section. The flow velocity of the drying gas is in this case at most 100 m/sec at the point where it is charged into the drying section. Within the drying section, the flow velocity of the tobacco material is also reduced along with the reduction in the flow velocity of the drying gas in order to reduce the local heat transfer coefficient and the local mass transfer coefficient between the surface of the tobacco material and the surrounding drying gas. At the end of the drying section, the drying gas has a flow velocity of at most 15 m/sec and a temperature of at most 130 DEG C. <IMAGE>
Patent ZA-924166-B (ZA)
Title: Battery with intergral condition tester.
Inventor: WANG CHIH-CHUNG
IPC: G01R19/165
Filed: 1992-06-08
Abstract: The combination of an electrochemical cell having two external termini, a label and a covered cell condition indicator;   said cell comprising: a sealed cylindrical container an outer surface whereof provides one of said termini; a cover sealing said container; a further one of said external termini; and means for conducting electricity from the inner side of said container to said further terminus; said indicator being disposed externally of said sealed container and comprising a resistance heating element and a thermochromic display and said resistance heating element having two electrical contacts which in the operation of said indicator are electrically conducted to respective said termini, characterised in that a contact is disposed to contact one of said termini and the other contact is disposed at the other one of said external termini of said sealed cylindrical container, the first of said contacts being separated from electrical contact with a first of said termini by an apertured insulator on the side of said cell whereby in operation of said indicator said first contact may be brought into electrical contact with said first terminus by application of external pressure to cause it to pass through an aperture in said insulator and come into electrical contact with said first terminus, and whereby said electrical contact is broken by removal of said external pressure, and in that said indicator is positioned between the external surface of said label and one of said first termini; and further characterised in that said thermal insulator is the minimum thickness necessary to permit the cell condition indicator to function reliably, said thermal insulation being positioned between said resistance heating element and the external surface of said cylindrical container.   <IMAGE>
Patent ZA-927211-B (ZA)
Title: Novel carboxyalkyl derivatives useful as inhibitors of enkephalinase and ACE.
Inventor: WARSHAWSKY ALAN M
IPC: A61P7/10
Filed: 1992-09-21
Abstract: The present invention relates to compounds of the formula <CHEM>  wherein   B<5> and B<6>   are each independently hydrogen; hydroxy; -OR<6> wherein R<6> is a C<5>-C<8> alkyl or an Ar-Y group wherein Ar is aryl and Y is a hydrogen or C<5>-C<8> alkyl; or, where B<5> and B<6> are attached to adjacent carbon atoms, B<5> and B<6> can be taken together with said adjacent carbons to form a benzene ring or methylenedioxy; A   is a bond, methylene or oxygen, sulfur or NR<8> or NCOR psi wherein R<8> is hydrogen, a C<5>-C<8> alkyl or an Ar-Y- group and R psi  is -CF<7>, a C<5>-C<5><4> alkyl or an Ar-Y- group; R<7>   is hydrogen or -CH<6>OC(O)C(CH<7>)<7>; R<5>   is hydrogen, C<5>-C<8> alkyl or -CH<6>OC(O)-C(CH<7>)<7>; and n   is an integer 1 to 3, which are useful as inhibitors of enkephalinase and ACE.
Patent ZA-935095-B (ZA)
Title: Process for the flow-dynamic manufacture of deformable fibre mats having a high tensile strenght and apparatus for the manufacture thereof
Inventor: BIERBAUMER WILHELM
IPC: D04H1/732
Filed: 1993-07-14
Abstract: Disclosed is a process for dynamic-flow production of ductile, highly tear-resistant fiber mats from a fibrous web consisting of cellulose fibers impregnated with a binder and thermoplastic fibers and/or natural, vegetable fibers, where the apparatus, arranged in the flow direction of the material, consists of a web forming machine (1), a pair of press rollers (3, 4), a pair of draw-in rollers (5), a cylinder (6), an air channel (10) which is fed by ventilators (12) and fitted with one or more control members (25) in the form of one or more adjustable flaps, a venturi rod (7), a diffuser (13), a mat forming roll (15), feed rollers (16, 17), a surface weight measuring device (19), a needle machine (20), a flattening device (21), a cutting machine (22) and a stacking device (24). Disclosed also is the use of a ductile, highly tear-resistant fiber mat produced by the process as per the invention, where one or more of the fiber mats (23, 23') is used for producing form pieces by pressing at elevated pressure and temperature.
Patent ZA-942203-B (ZA)
Title: Sunshade
Inventor: STEINER WALTER
IPC: A45B11/00
Filed: 1994-08-26
Abstract: The sun umbrella has a central head with a number of relatively pivoted support rods, to which the umbrella sections (17) are attached and a support mast with a sliding element having attached support struts for holding the support rods. The umbrella sections are formed from a pleated material with the pleat fold lines extending radially relative to the central head, so that they fold together in a zigzag configuration when the umbrella is closed.
Patent ZA-952367-B (ZA)
Title: An identity card protected from unauthorized reproduction with a copying machine
Inventor: SOLMSDORF BERNHARD
IPC: B42D15/10
Filed: 1995-03-23
Abstract: A permit or access card has a laminated structure with a transparent cover (6) located over a metal layer (7) that is used to create an area providing protection against copying. The metal layer is formed over a layer (8) having specific optical characteristics and this is formed on an opaque layer (18). An identification pattern is formed in the metal layer with the aid of a laser. The layer beneath the metal layer has a specific optical characteristic corresponding to a part of the visible spectrum. The characteristics of the layer prevent the pattern alone or in combination with the metal layer from being exactly electrophotographically copied. The pattern may also be produced as a holographic image.
Patent ZA-959721-B (ZA)
Title: Halogenated esters useful as intermediates for insecticides
Inventor: BOWDEN MARTIN CHARLES
IPC: C07C69/675
Filed: 1995-11-15
Abstract: The invention provides novel compounds of formula:CF3-CXCl-CH(OH)CH2-C(CH3)2-CH2-CO2R(I)where X represents chloro or bromo and R represents hydrogen or alkyl of up to 4 carbon atoms, processes for preparing them and their use as intermediates in the preparation of insecticidal cyclopropane derivatives. Also provided are novel compounds of formula:BrCH2-CH2-C(CH3)2-CH2-CO2R(IV)wherein R represents alkyl of up to 4 carbon atoms, useful as intermediates in the preparation of the compounds of formula I.
Patent ZA-989800-B (ZA)
Title: Downloading of applications in a digital recorder
Inventor: SARFATI JEAN-CLAUDE
IPC: H04N5/00
Filed: 1998-10-28
Abstract: A method for downloading an executable application into a decoder 1 for a digital broadcast system, characterised in that the application is stored on a portable memory card introduced into a card reader 6, 7 in the decoder, the decoder reading and downloading the application from the card. Data may preferably be stored in the smartcard in a broadcast data format such as the MPEG format to permit the processing of such data in the same manner as the control unit 40 of the decoder processes data downloading by a broadcast transmission. The invention extends equally to a decoder and a memory card for use in such a method. <IMAGE>
Patent AT-414095-B (AT)
Title: Preparation useful e.g. to treat dry mucous membrane in oral and throat area comprises medical and/or food organic substance, flavor material, mucoadhesive substance, sugar (alcohol) and carrier substance e.g. fat and/or oil
IPC: A61K9/00
Filed: 2003-03-11
Granted: 2006-09-15
Abstract: Preparation (I) for the treatment of dry mucous membrane in the oral and throat area, which is accompanied by negative conditions e.g. swallowing difficulties, comprises at least a medically compatible and/or food organic substance; at least a medically compatible and/or food regulating certified flavor material; mucoadhesive substance; a sugar and sugar alcohol; and a carrier substance such as fat and/or oil and further a linking agent such as triglyceride and/or hydrophobic liquid, which exhibits lubricating action. Preparation for the treatment of dry mucous membrane in the oral and throat area, which is accompanied by negative conditions such as swallowing difficulties, foreign body sensation in the neck area and pharyngitis, comprises at least a medically compatible and/or food regulating organic substance (15-60 (preferably 20-25)%) such as citric acid, tartaric acid, maleic acid, gluconic acid, ascorbic acid, succinic acid or adipic acid, as a salivation promoting substance (5-25 (preferably 10-20)%); at least medically compatible and/or food regulating certified flavor material; at least a mucoadhesive substance (25-70 (preferably 50-65)%) such as modified cellulose, hydroxymethyl, hydroxyethyl, hydroxypropyl, hydroxypropylmethyl and sodiumcarboxymethylcellulose, polyvinylpyrrolidone, polyethyleneglycol, tragacanth, gum arabic, gelatin, agar-agar, polyacrylic acid and/or polycarbophil; a sugar and sugar alcohol such as glucose, fructose, mannose, maltose, sorbitol, xylitol, mannitol, and synthetic sweetener (saccharin, acesulfame, cyclamate, aspartame and/or its salts); and a carrier substance such as fat and/or oil (almond oil, peanut oil, olive oil, sesame oil, linseed oil, rapeseed oil, mawseed oil, behen oil, and/or neutral oil), and further a linking agent (triglyceride and/or hydrophobic liquid (silicone oil, liquid paraffins and/or low fatty acids (preferably isopropyl myristate, isopropyl palmitate, ethyl and/or oleyl oleate)), which exhibits lubricating action, where (I) is present as gel and in amount of 0.5-5 (preferably 2-3)%. Independent claims are included for: (1) a dental prosthesis-adhesive cream and/or hard gel comprising (I); and (2) a carrier substance of fat and/or oil useful in the manufacture of (I) for mouth area and disrupted area. ACTIVITY : None given. MECHANISM OF ACTION : None given.