baber/WOPTO huggingface dataset:
Patent SG-11201803593Q-A (SG)
Title: Engineered nucleic-acid targeting nucleic acids
Inventor: DONOHOUE PAUL
IPC: C12N15/113
Filed: 2016-12-02
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 8 June 2017(08.06.2017) WIPOIPCT (10) International Publication Number WO 2017/096328 A1 (51) International Patent Classification: C12N15/10 (2006.01) C12N15/113 (2010.01) C12N15/11 (2006.01) (21) International Application Number: PCT/US2016/064860 (22) International Filing Date: (25) Filing Language: (26) Publication Language 2 December 2016 (02.12.2016) English English (84) (30) Priority Data: 62/263,232 4 December 2015 (04.12.2015) US (71) Applicant: CARIBOU BIOSCIENCES, INC. [US/US]; 2929 7th Street, Suite 105, Berkeley, CA 94710 (US). (72) Inventors: DONOHOUE, Paul, Daniel; 2929 7th Street, Suite 105, Berkeley, CA 94710 (US). MAY, Andrew, Paul; 2929 7th Street, Suite 105, Berkeley, CA 94710 (US). (74) Agents: MCCLUNG, Barbara et al.; Caribou Bios­ ciences, Inc., 2929 7th Street, Suite 105, Berkeley, CA 94710 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) with sequence listing part of description (Rule 5.2(a)) < 00 n ON n O (54) Title: ENGINEERED NUCLEIC-ACID TARGETING NUCLEIC ACIDS 229 227 228 FIG. 2C (57) : The present disclosure provides engineered polynucleotide sequences that form scaffolds and nucleoprotein com­ plexes comprising such engineered polynucleotide sequences that form scaffolds and nucleic acid binding proteins. Nucleic acid se - quences encoding the engineered polynucleotide sequences that form scaffolds, as well as expression cassettes, vectors and cells comprising such polynucleotide sequences, are described. A variety of methods for making and using the engineered polynucleotide sequences that form scaffolds are also disclosed.
Patent SG-11201900868X-A (SG)
Title: Ido1 inhibitor and preparation method and application thereof
Inventor: ZHANG YANG
IPC: C07D413/12
Filed: 2017-08-02
Abstract: A compound as an indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor, and an application thereof in the field of IDO1-related diseases, and in particular a compound as shown in formula (I) and a pharmaceutically acceptable salts thereof.
Patent SG-11201908177R-A (SG)
Title: Method of electrochemically producing hydrogel, method of producing hydrogel with pattern formed of cells, hydrogel production apparatus, and transducer
Inventor: INO KOSUKE
IPC: C12M1/34
Filed: 2018-01-24
Abstract: [ OF THE DISCLOSURE] A hydrogel is formed by a reaction which is induced, in an electrolytic solution, by an electrode product electrochemically generated by electrodes installed in the electrolytic solution. An apparatus including an electrolytic tank with a bottom surface on which a two-dimensional array of working 5 electrodes is provided and a counter electrode installed in the electrolytic tank is prepared. An electrolytic solution containing a dissolved substance that causes electrolytic deposition of a hydrogel is housed in the electrolytic tank. By applying a predetermined voltage to one or more selected working electrodes of the two-dimensional array, a hydrogel with 10 a two-dimensional pattern corresponding to the arrangement of the selected working electrodes is formed.
Patent AT-393738-B (AT)
Title: Length-measuring method
IPC: G01S13/08
Filed: 1989-01-16
Granted: 1991-12-10
Abstract: In order to determine the length of columns of a liquid, solid or gaseous medium, a standing wave of known frequency, wavelength and/or wave velocity is generated in the medium column. The frequency of the wave is varied until at least two successive maxima (oscillation antinodes), two successive minima (oscillation nodes) or a minimum following a maximum are detected in the amplitude of the standing wave. The length of the medium column is calculated, given a known frequency and wave velocity of the standing wave generated in the medium column, using the formula 1, in which L is the length of the medium column, c is the wave velocity, fn is the frequency of the nth maximum, and fn-1 is the frequency of the (n-1)th maximum.
Patent AT-404906-B (AT)
Title: Method of removing deposits
Inventor: PRODINGER KARL DIPL ING DR
IPC: B08B9/00
Filed: 1995-03-09
Granted: 1999-03-25
Abstract: The invention proposes a process for removing deposits adhering to, in particular, submersed surfaces by treatment with a gaseous pressure medium, in particular steam, characterized in that the pressure medium treatment is superposed by an ultrasound treatment.
Patent AT-406169-B (AT)
Title: Three-dimensional, form-stable shaped article based on structured needlefelts
Inventor: HAMMERSCHMIDT JOHANN
IPC: D04H1/48
Filed: 1998-03-12
Granted: 2000-03-27
Abstract: Three-dimensional, form-stable shaped articles consisting of a two- or multilayered structure-needled needlefelt of thermoplastic fibres comprising a first layer of a mixture of polypropylene (PP) fibres and polyethylene (PE) fibres and a second and optionally further layers of a mixture of PP fibres and PE fibres; or of biconstituent fibres consisting of a mixture of PP and PE; or of a mixture of these biconstituent fibres and PP fibres and/or PE fibres, wherein the two layers are consolidated and connected together not only through needling but also through molten or fused fibres or fibre portions of the PE fraction of the two layers, and a process for producing these shaped articles.
Patent AT-397040-B (AT)
Title: Marker pole
IPC: A63C19/06
Filed: 1992-03-06
Granted: 1994-01-25
Abstract: An inflatable marker pole, especially a ski gate pole, wherein an airtight body of a flexible, elastic material which is substantially cylindrical in the inflated state and closed or closable at its two ends can be inserted into a holder anchored in the ground having a lengthwise section projecting above the ground which possesses a preferably central bore, open at the top, for receiving the body. In order for the individual parts of such a marker pole to be easily exchangeable, it is proposed that the body 4 be surrounded by an enclosure tube 5 of a flexible material, for example a synthetic fibre fabric, which preferably extends over the entire length of the body 4. <IMAGE>
Patent DK-158409-B (DK)
Inventor: REHNER HELMUT
IPC: G01N33/96
Filed: 1982-02-15
Abstract: Control serum containing (1) at least one compound of the formula: <IMAGE>  (I)  in which T is hydrogen or methyl, hydroxymethyl or methoxymethyl X is hydrogen hydroxymethyl or methyl when Y is hydroxyl, hydroxymethyl or NR2; Y is hydrogen, hydroxyl, hydroxylmethyl or NR2 and Z is hydroxyl or an -O-CH2-CH2OH group when Y is hydrogen or hydroxymethyl, or Z is hydroxymethyl or a carboxyl derivative or T is ethyl or isopropyl, X is hydrogen, or methyl, hydroxymethyl or methoxy, Y is hydroxy, hydroxymethyl or NR2 and Z is a carboxyl derivative; each R independently is hydrogen or an alkyl group with 1 to 2 carbon atoms optionally containing a hydroxy group and/or (2) at least one compound of the formula HO(CH2-CH2-O)nH, (II) in which n is an integer from 2 to 8, in an amount sufficient to reduce turbidities in reconstituted serum after previous lyophilization.
Patent HU-191511-B (HU)
Inventor: FORIAN GABOR
IPC: E05F15/04
Filed: 1983-01-25
Abstract: Die Erfindung bezweckt die Bereitstellung einer Aussenschwingtuer mit einer Betaetigungseinrichtung, die bei einfachem Aufbau auch die Sicherheitsbedingungen restlos erfuellt, keine kostspieligen und komplizierten Herstellungstechnologien benoetigt und auch in bestehenden Fahrzeugen leicht nachruestbar ist. Als Loesung ist nunmehr eine Aussenschwingtuer mit Betaetigungseinrichtung, wobei letztere einen mit einer Drehsaeule verbundenen Antrieb aufweist und auf der Drehsaeule mindestens ein Schwenkarm befestigt ist, der an einem Punkt der Aussenschwingtuer angelenkt ist, wobei erfindungsgemaess mindestens ein Punkt der Aussenschwingtuer waehrend ihrer Bewegung auf einem Teil eines Kreisbogens und mindestens ein sich vom vorherigen unterscheidender Punkt der Aussenschwingtuer waehrend mindestens eines Teiles ihrer Bewegung linear fuehrbar sind, wobei der auf dem Teil eines Kreisbogens gefuehrte Punkt der Aussenschwingtuer mit dem Schwenkarm der Drehsaeule verbunden ist. Fig. 3
Patent HU-192864-B (HU)
Title: Process for preparing new lipopeptides
Inventor: BASCHANG GERHARD
IPC: C07K5/06
Filed: 1984-01-23
Abstract: The invention relates to lipopeptides of the formula I,    <IMAGE> (I)  * = -R** = -R or -S*** = -R  in which each of Ra1 and Rb1, independently of the other, represents an aliphatic or cycloaliphatic-aliphatic hydrocarbon radical having from 7 to 21 carbon atoms that is optionally substituted by oxygen functions, or one of the radicals Ra1-CO- and Rb1-CO- represents hydrogen and the other of the radicals Ra1-CO- and Rb1-CO- represents an acyl radical, wherein Ra1 and Rb1 have the meanings given above, R2 represents an aliphatic or cycloaliphatic-aliphatic hydrocarbon radical having from 1 to 21 carbon atoms that is optionally substituted by oxygen functions, n=0 or 1, As DEG  represents a radical of the formula -O-Kw-CO- or -NH-Kw-CO- wherein Kw represents an aliphatic hydrocarbon radical having a maximum of 12 carbon atoms, As1 represents a D- or L- alpha -amino acid, each of Z1 and Z2, independently of the other, represents hydroxy or the N-terminal radical of a D- or L- alpha -aminocarboxylic acid, of an amino-lower alkanesulphonic acid or of a peptide having a maximum of 6 amino acids from the group consisting of D- or L- alpha -aminocarboxylic acids and amino-lower alkanesulphonic acids, and Z3 represents hydrogen or -CO-Z4 wherein Z4 represents hydroxy or the N-terminal radical of a D- or L- alpha -amino acid, of an amino-lower alkanesulphonic acid or of a peptide having a maximum of 6 amino acids from the group consisting of D- or L- alpha -aminocarboxylic acids and amino-lower alkanesulphonic acids, and the amides and esters of such compounds that contain carboxy groups. The novel lipopeptides have an immunity-stimulating action.
Patent MX-165919-B (MX)
Title: Mejoras en un aspersor miniatura giratorio para sistemas de irrigacion
Inventor: RUBINSTEIN ZVI
IPC: B05B3/04
Filed: 1985-11-13
Abstract: La presente invención se refiere a mejoras en un aspersor miniatura giratorio para sistemas de irrigación, en donde el aspersor comprende: una boquilla fija que se extiende verticalmente, teniendo un taladrado axial, una entrada en ella para comunicación con una tubería de suministro y una salida en la misma boquilla; caracterizadas las mejoras por: un desviador de flujo giratorio que tiene una entrada dispuesta a lo largo de un primer eje longitudinal que se comunica con la salida de la boquilla en coincidencia axial con la misma y que se fusiona con al menos una salida que se inclina a lo largo de un eje longitudinal, lateral a dicho primer eje, formada para asegurar la emisión de agua desde la misma en forma de chorro; y un deflector de agua giratorio asociado con dicho desviador de flujo giratorio, el deflector de agua teniendo al menos una pared deflectora y estando colocado de manera tal que en cualquier posición del desviador, al menos parte del flujo que proviene de la o las salidas de dicho desviador, sea desviado por las o al menos una de las paredes deflectoras en una dirección para provocar la rotación del desviador de flujo en la dirección opuesta; en donde el desviador de flujo es también movible lado a lado de dicho primer eje con relación a la boquilla durante el uso.
Patent YU-48885-B (YU)
Inventor: INZ VUCKOVIC VLADAN DIPL
Filed: 1996-12-23
Abstract: Sistem napajanja energijom niskonaponskih fluorescentnih lampi korišćenjem pulsirajuće jednosmerne struje, sastoji se od startera (8) vezanog paralelno sa fluorescentnom lampom (4) preko kontakata (7) i (5), izvora za napajanje naizmeničnom strujom iz gradske mreže (1) koji je redno vezan sa prigušnicom (2), naznač en time, što je Grecov ispravljački stepen (3), vezan sa jedne strane preko prigušnice (2) za izvor naizmenične struje (1), a sa druge, preko kontakata (6) i (5) za lampu (4) i što je ostvareno vezivanje lampe (4) preko tri kontakta (elektrode) na sistem napajanja tako što su dva kontakta na pozitivno polarisanom kraju lampe vezana u kratkom spoju tako da čine jedinstveni kontakt (5).
Patent YU-48188-B (YU)
Inventor: HARTMANN E
IPC: B30B9/26
Filed: 1992-08-19
Abstract: PCT No. PCT/CH92/00170 Sec. 371 Date May 28, 1993 Sec. 102(e) Date May 28, 1993 PCT Filed Aug. 26, 1992 PCT Pub. No. WO93/06988 PCT Pub. Date Apr. 15, 1993.The rod-shaped flexible core (6) of a drainage element (2) mounted in a pressing space (1) of a fruit press has several longitudinal grooves (8, 13) on its periphery, through which the extracted juice is conveyed to juice collecting spaces (5). The free ends of each drainage element (2) are detachably fastened by drainage locks (3) to juice collecting plates (4) bordering the pressing space (1). In the area of rigid drainage lock (3), through which the juice is guided, the longitudinal grooves (8) are widened, so that in this area, in which the flexibility of core (6) to assist the flow process is absent, the risk of clogging by solid sediment particles in the juice is prevented.
Patent RS-50246-B (RS)
Title: Ambroxol-containing lozenge
Inventor: MAERZ FRIEDER ULRICH
IPC: A61K31/137
Filed: 2000-07-07
Abstract: An amobroxol (I)-containing suckable tablet, based on a sugar alcohol matrix material, additionally contains a layered silicate (II), a polyethylene glycol (III) and optionally further auxiliaries, flavorings or aromas.  An Independent claim is included for the preparation of the tablet, by mixing the components conventionally and pressing the mixture into a tablet (preferably by direct pressing).
Patent AT-398082-B (AT)
Title: Treatment of fleece fibres
IPC: D01G15/20
Filed: 1993-06-18
Granted: 1994-09-26
Abstract: (To be reissued in later week based on complete specification).
Patent AT-402992-B (AT)
Title: Portioning device for chaff fodder pressed into round bales
IPC: A01F15/00
Filed: 1995-07-24
Granted: 1997-10-27
Abstract: Portioning device for chaff fodder pressed into round bales, in particular wrapped silage bales, with a conveying device 1, 10 which forms a trough 5 for receiving a fodder bale 4 and which, for the purpose of taking up the round bale 4 without entanglement, is formed either by a multiplicity of closely adjacent drivable smooth-walled rollers 1 or by a smooth-surfaced conveyor belt 10 laid loosely over two driving rollers 12 located at a distance from one another. This device is expediently capable of being moved, specifically in the longitudinal direction of the trough 5. <IMAGE>
Patent AT-400020-B (AT)
Title: Injection unit for an injection-moulding machine
Inventor: LAMPL ALFRED DIPL ING DR
IPC: B29C45/76
Filed: 1992-07-07
Granted: 1995-09-25
Abstract: An injection unit for injection-moulding machines for injecting a plurality of polymer components. Two melt cylinders 1, 2 in which plasticizing screws 3, 4 are arranged such that they can rotate and be displaced are provided.  The melt cylinders 1, 2 are connected via feed channels 8, 9 to a common injection channel 10, which leads to an injection nozzle 11. A shut-off slide valve 13 for the feed channels 8, 9 is provided and also injection pistons 5 with which the plasticizing screws 3, 4 can be displaced. A control device 16 is provided, by means of which the plasticizing screws 3, 4 can be displaced by the injection pistons 5 at different speeds over the same time period during the injection operation. Arranged in at least one of the feed channels 8 is a device 14 for viscosity measurement, which is connected to the control device 16 and by means of which the rate of advance of the associated plasticizing screw 3 can be controlled in dependence on the viscosity measurement during the injecting operation. <IMAGE>
Patent DK-165697-B (DK)
Title: Process for rapidly after-curing polyether polyurethane foamed material blocks
Inventor: GRISWOLD AZEL ALAN
IPC: C08G18/00
Filed: 1986-05-02
Abstract: A process for the rapid post curing of polyether polyurethane foam in the form of porous blocks in which the foam is subjected to a mixture of water vapor and gaseous ammonia, primary or secondary amines at a temperature of about 50 to 150° F. For a period of 1 or more minutes. The cured foam recovers its original dimensions when distorted or compressed after the distortion or compression force is released.
Patent DK-163064-B (DK)
Inventor: BANKERT RALPH ALLEN
IPC: C08F8/44
Filed: 1981-05-29
Abstract: Process of producing quaternary ammonium compounds from tertiary amines, without the use of epihalohydrin as the quaternization agent, comprising reacting an amino compound containing at least one tertiary amine group with an allyl halide to quaternize the amine and then reacting the quaternized product with hypohalous acid to convert the allyl substituents to halohydrin moieties.
Patent DK-162693-B (DK)
Title: Clothes hanger for hanging several items of clothing
Inventor: ROESCH WILHELM
IPC: A47G/
Filed: 1989-05-24
Abstract: PCT No. PCT/DE88/00420 Sec. 371 Date Jun. 13, 1989 Sec. 102(e) Date Jun. 13, 1989 PCT Filed Jul. 7, 1988 PCT Pub. No. WO89/02714 PCT Pub. Date Apr. 6, 1989.A garment hanger for supporting several articles of clothing. The garment hanger has a plurality of U-shaped carrying bars that are telescopically, rotatably and slidably mounted in a carrying element. The garment hanger can be hung on a closet clothes bar so that a plurality of articles can be hung in a narrow space. The garment hanger is configured so that if one of the carrying bars is pulled out, the carrying bars that remain in position act as counter weights to balance the entire garment hanger system.
Patent DK-164630-B (DK)
Inventor: LOCHER HERMANN
IPC: A47C1/032
Filed: 1985-10-02
Abstract: A reclining seat support (3) and a backrest support (4) are hinged on a chair frame with a support part (1) via a lever (7) by means of hinges (5, 8). Coupled to the backrest-side end of the seat support (3) is a link chain (15) which is connected at its other end to a slide (20) and a backrest (21). The link chain (15) causes the slide (20) to be moved downwards with the backrest when the chair is reclined. By this means, the pulling-out effect during the transition from the normal position into the reclined position of the lever is eliminated. However, if the chair frame is used as a chair without a link chain (15), although slightly less seating comfort is achieved by the reclining seat support, the expenditure is correspondingly less. <IMAGE>
Patent FI-66981-B (FI)
Inventor: KALBERER FELIX
IPC: F28D21/00
Filed: 1982-01-29
Granted: 1984-08-31
Abstract: Waste water is led into a container (1) through a inlet (4) at the top. A connection (20) between the inlet (4) and an outlet (21) having a check valve (22) comprises adjacent to the inlet (4) two inverted frusto-conical hollow bodies (24, 25) which are directly connected to each other. The connecting surface between the two hollow bodies (24, 25) is formed as a coarse screen (26). A round fine screen (30), which diverges downwardly, surrounds the hollow bodies (24, 25). Heat exchangers (31) are located in the space between the fine screen (30) and the wall (2) of the container (1). An outlet (5) terminates at the bottom of the container and connects with a riser (6) and via a bend (7) with the sewerage conduit (8). Through the coarse screen (26) the waste water reaches the container, and the heat can reach the heat exchangers (31) through the fine screen (30 ), so that practically uncontaminated water is present at the heat exchangers, and the need for cleansing is substantially diminished.
Patent FI-79706-B (FI)
Inventor: IDE JUNYA
IPC: C07D309/30
Filed: 1982-09-24
Granted: 1989-10-31
Abstract: Compounds of formula (I):   <IMAGE> (I)  [wherein X represents a hydrogen atom or a 2-methylbutyryl group, Y represents a hydrogen atom or a methyl group and R1 and R2 are the same or different and each represents an oxygen atom or a group of formula =N-OR3 (wherein R3 represents a hydrogen atom or an alkyl group)], the free hydroxy-carboxylic acids corresponding thereto and salts and esters of said acids may be prepared by oxidizing and, if necessary, oximating a corresponding ML-236A, ML-236B, MB-530A or MB-530B compound, and these compounds have valuable antihypercholesteraemic activity.
Patent FI-74039-B (FI)
Inventor: DRAWERT MANFRED
IPC: C08G69/34
Filed: 1983-10-04
Granted: 1987-08-31
Abstract: Polyamides which are alcohol-soluble at room temperature, are useful in formulating printing inks, and which comprise dimerized fatty acids, at least one aliphatic unbranched monocarboxylic acid and at least one aliphatic branched monocarboxylic acid as the acid component, and ethylenediamine and hexamethylenediamine as the amine component, and printing inks formulated therefrom.
Patent FI-87524-B (FI)
Inventor: WENZEL BRUCE E
IPC: A61K31/355
Filed: 1987-01-16
Granted: 1992-10-15
Abstract: A dry, particulate, free-flowing form of Vitamin E (α-tocoph­erol) is provided which includes a potency stabilizer for the Vitamin E. The potency stabilizers are hydroxy acids or amino acids such as ascorbic acid, citric acid, methionine and cysteine.
Patent FI-90766-B (FI)
Inventor: CHANDRARATNA ROSHANTHA A S
IPC: A61K31/455
Filed: 1987-12-22
Granted: 1993-12-15
Abstract: Retinoid-like activity is exhibited by compounds of the formula <CHEM> wherein A is pyridyl, furyl, thienyl, pyridazinyl, pyrimidinyl or pyrazinyl; n is 0-5; and B is H, -COOH and its esters, amides and pharmaceutically acceptable salts, -CHO and its acetal derivatives, -COR1 and its ketal derivatives where R1 is -(CH2)nCH3 where n is defined above, or -CH2OH and its ether and acyl ester derivatives; or a pharmaceutically acceptable salt.
Patent FI-106751-B (FI)
Inventor: BOUTIER PHILIPPE
IPC: F15B5/00
Filed: 1989-06-16
Granted: 2001-03-30
Abstract: The invention relates to a method and a device for detecting a moving glass sheet heated to a temperature above its softening point. A jet of pressurised gas, in particular compressed air, is sent through the path which the sheet of glass takes, and the variation in pressure of the jet when the latter is intersected by the sheet of glass is detected. <IMAGE>