Patent EA-001584-B1 (EA)
Title: Process and composition for the antiparasitic treatment of the surroundings of animals
Inventor: JEANNIN PHIIPPE
IPC: C05G3/60
Filed: 1997-07-17
Abstract: 1. Process for the antiparasitic treatment of sites infested or capable of being infested by darkling beetles, in which an effective amount of a composition comprising at least one compound corresponding to the formula (I)   in which: R1 is a halogen atom or a CN or methyl group; R2 is S(O)nR3 or 4,5-dicyanoimidazol-2-yl or haloalkyl; R3 is alkyl or haloalkyl; R4 represents a hydrogen or halogen atom; or an NR5R6, S(O)mR7, C(O)R7 or C(O)O-R7, alkyl, haloalkyl or OR8 radical or an -N=C(R9)(R10) radical; R5 and R6 independently represent a hydrogen atom or an alkyl, haloalkyl, C(O)alkyl, alkoxycarbonyl, S(O)rCF3 radical; or R5 and R6 can together form a divalent alkylene radical which can be interrupted by one or two divalent heteroatoms, such as oxygen or sulphur; R7 represents an alkyl or haloalkyl radical; R8 represents an alkyl or haloalkyl radical or a hydrogen atom; R9 represents an alkyl radical or a hydrogen atom; R10 represents a phenyl or heteroaryl group optionally substituted by one or a number of halogen atoms or groups such as OH, -O-alkyl, -S-alkyl, cyano or alkyl; R11 and R12 represent, independently of one another, a hydrogen or halogen atom and optionally CN or NO2 but H or halogen are preferred; R13 represents a halogen atom or a haloalkyl, haloalkoxy, S(O)qCF3 or SF5 group; m, n, q and r represent, independently of one another, an integer equal to 0, 1 or 2; X represents a trivalent nitrogen atom or a C-R12 radical, the other three valencies of the carbon atom forming part of the aromatic ring; with the proviso that. when R1 is methyl, then either R3 is haloalkyl, R4 is NH2, R11 is Cl, R13 is CF3 and X is N; or else R2 is 4,5-dicyanoimidazol-2 -yl, R4 is Cl, R11 is Cl, R13 is CF3 and X is =C-Cl, is applied to the said site. 2. Process according to Claim 1, in the formula (I) of which R1 is CN and/or R3 is haloalkyl and/or R4 is NH2 and/or X is CR12 and/or R11 and R1.2 are, independently of one another, a halogen atom and/or R13 is haloalkyl. 3. Process according to either of the preceding claims. in which the compound of formula (I) is 1-[2,6-Cl2-4-CF3phenyl]-3-CN-4-[SO-CF3]-5-NH2pyrazole, hereinafter known as compound A. 4. Process for the antiparasitic treatment of the surroundings of animals, in which an effective amount of a compound of formula (I) as defined in one of Claims 1 to 3 is applied. 5. Process according to one of the preceding claims. in which the treated sites are the floor or a litter or a liquid manure or a place or a building or a building for commercial rearing. 6. Process according to one of the preceding claims, in which the treated sites are the floor or a litter or a liquid manure or a place or a build ing or a building for commercial rearing intended to receive poultry. 7. Process according to one of the preceding claims, in which the treated sites are infested or capable of being infested by Alphitobius diaperinus. 8. Process according to one of the preceding claims, in which the treated sites are infested or capable of being infested by Dermestes maculatus, Tenebrio molitor or a darkling beetle from the Tenebrionidae family. 9. Process according to one of the preceding claims, in which the treatment is carried out at a frequency of less than once per month. 10. Process according to one of the preceding claims, in which the treatment is carried out at a frequency not exceeding once per rearing cycle. 11. Process according to one of the preceding claims, in which the treatment is carried out with a composition containing from 0.00001 to 95 % of active material(s) of formula (I), preferably 0.5 to 90 %.  12. Process according to one of the preceding claims, in which the treatment is carried out with a composition having a surface-active agent content of between 2 % and 40%. 13. Process according to one of the preceding claims, in which the treatment is carried out from a composition in the dispersible granule or suspen sion or emulsifiable concentrate form. 14. Process according to one of the preceding claims. in which the treatment is carried out from a composition in the form of a dispersible granule with a density of between 0.2 and 0.8, preferably between 0.3 and 0.6, and with a siz e of between 0.1 and 3 mm, preferably between 0.3 and 1.5 mm. 15. Process according to one of the preceding claims, in which the treatment is carried out by application of the active material of formula (I) at the rate of 0.05 to 100 mg per m<2>, preferably between 0.5 and 50 mg/m<2> and more preferentially still between 10 and 15 mg/m. 16. Process according to one of the preceding claims, in which the treatment is carried out in the absence of animals. 17. Process according to one of the preceding claims, in which a floor or litter or liquid manure is treated at the rate of 0.01 to 50 mg of active material of formula (I) per kg of ready-to-use litter, preferably of 0.1 to 10 m g/kg. 18. Animal litter comprising an effective amount of antiparasitic active material of formula (I) as defined in one of Claims 1 to 3. 19. Poultry litter comprising an effective amount of antiparasitic active material of formula (I) as defined in one of Claims 1 to 3. 20. Floor, comprising an effective amount of antiparasitic active material of formula (I) as defined in one of Claims 1 to 3. 21. Floor according to Claim 20, comprising between 0.05 and 100 mg per m<2>, preferably between 0.5 and 50 mg/m<2> and more preferentially still between 10 and 15 mg/m<2> of antiparasitic active material of formula (I). 22. Floor according to Claim 20, comprising between 0.01 and 50 mg of active material of formula (I) per kg of ready-to-use litter, preferably from 0.1 to 10 mg/kg. 23. Litter, comprising comprising an effective amount of antiparasitic active material of formula (I) as defined in one of Claims 1 to 3. 24. Litter according to one of Claims 18, 19, 23, comprising between 0.05 and 100 mg per m<2>, preferably between 0.5 and 50 mg/m<2> and more preferentially still between 10 and 15 mg/m<2> of antiparasitic active material of formula (I). 25. Litter according to one of Claims 18, 19, 23, comprising between 0.01 and 50 mg of active material of formula (I) per kg of ready-to-use litter, preferably from 0.1 to 10 mg/kg. 26. Liquid manure, comprising an effective amount of antiparasitic active material of formula (I) as defined in one of Claims 1 to 3. 27. Liquid manure according to Claim 26, comprising between 0.05 and 100 mg per m<2>, preferably between 0.5 and 50 mg/m<2> and more preferentially still between 10 and 15 mg/m<2> of antiparasitic active material of formula (I). 28. Liquid manure according to Claim 26, comprising between 0.01 and 50 mg of active material of formula (I) per kg of ready-to-use litter, preferably from 0.1 to 10 mg/kg.