baber/WOPTO huggingface dataset:
Patent CA-2511052-C (CA)
Title: Rotor blade for a wind power plant
Inventor: WOBBEN ALOYS
IPC: F03D1/06
Filed: 2003-12-19
Granted: 2009-07-14
Abstract: The present invention concerns a rotor blade for a wind power plant having an aerodynamic profile comprising a rotor blade leading edge and a rotor blade trailing edge. The invention also concerns a rotor blade tip for a rotor blade having an aerodynamic profile with a pressure and a suction side, wherein the rotor blade tip is curved or angled in its end region in t he direction of the pressure side of the rotor blade. In order further to reduce the levels of sound emission of wind power plants the rotor blade is curved or angled in its edge region in the directi on of the trailing edge of the rotor blade in the plane of the rotor blade. In that respect the invention is based on the realisation that, in the case of a rot or blade which does not go to a point at the tip, the effective rotor blade are a is maintained unreduced precisely in the outer region in which the effect is greatest. The curve or angling of the end region of the rotor blade however provides that the trailing edge is displaced rearwardly in the end region of the rotor blade so that the flow at the rotor blade trailing edge is detache d with a time delay in the outer region. Alternatively to attain the object of the invention a rotor blade can be developed in such a way that the 'outer region' narrows. That configuration of the rotor blade tip is based on the realisation that the decreasing blade depth results in a reduced flow around the blade tip as the energy thereof is previously distributed to the trailing edge vortices but at the same time the effective rotor blade area is also reduced. The angling of the rotor bla de tip provides that the effective rotor blade depth remains at its optimum as far as the angled rotor blade tip.
Patent CA-2511755-C (CA)
Title: 1-desamino-8-d-arginyl vasopressin analogs
Inventor: GOMEZ DANIEL E
IPC: C07K7/16
Filed: 2003-12-29
Granted: 2012-05-15
Abstract: 1. Analogs of 1-desamino-8-D-arginyl vasopressin with the following general formula Mpa-Tyr-Phe-X-Y-Cys-Pro-D-Arg-Gly-NH2 wherein, X is an amino acid of the group consisting of alanine, asparagine, glutamine, isoleucine, leucine and valine; and Y is an amino acid of the group consisting of asparagine, glutamine, isoleucine, leucine and valine. 2. Analogs of 1-desamino-8-D-arginyl vasopressin, as claim 1, with the following general formula (I):  wherein, X is an amino acid of the group consisting of alanine, asparagine, glutamine, isoleucine, leucine and valine; and is an amino acid of the group consisting of asparagine, glutamine, isoleucine, leucine and valine.
Patent CA-2513717-C (CA)
Title: Novel use of mifepristone and derivatives thereof as hedgehog protein signalling pathway modulators and applications of same
Inventor: RUAT MARTIAL
IPC: A61K31/575
Filed: 2004-01-22
Granted: 2012-04-17
Abstract: The use of estra-4,9-dien-3-one derivative steroid compounds (including D-homo-steroid analogs) (I) (i.e. mifepristone (Ia) and related compounds) as medicaments for modulating the hedgehog protein signaling pathway, and treating disorders involving tissue dysfunction associated with deregulation of the pathway, is new.  The use of steroid or D-homo-steroid compounds of formula (I) or their salts is claimed in the production of medicaments for modulating (i.e. activating or inhibiting) the hedgehog protein signaling pathway and treating disorders involving tissue dysfunction associated with deregulation of the pathway.  R1  =  1-18C organic group, containing at least one N, P or Si atom and bonded to the steroid nucleus via C;  R2  =  1-8C hydrocarbyl;  X  =  tri- or tetramethylene group (or unsaturated equivalent), completing a 5- or 6-membered, saturated or unsaturated ring, optionally substituted by one or more of Q1 (optionally substituted by one or more groups Q2) and/or Q2;  Q1  =  alkyl, alkenyl, aryl or aralkyl or up to 12C;  Q2  =  OH, CHO, COX1, OX2, COOX3, OCOX4, halo, SH, SX5, SOX6 or SO2X7;  X1 - X7  =  1-8C alkyl, 2-8C alkenyl, 2-8C alkynyl, 6-15C aryl or 6-15C aralkyl;  C = A = oxo (optionally in ketal-blocked form), CH-OH, CH-OY1, 'alkylcarboxylate -C(=H)(=O)-C(=O)-Y2' (sic), C=NOY3 or CH2;  Y1 - Y3  =  1-8C alkyl or 7-15C aralkyl;  A1 + A2  =  additional C-C bond or -O- (epoxide).
Patent CA-2528098-C (CA)
Title: Internally cooled gas turbine airfoil and method
Inventor: PAPPLE MICHAEL
IPC: F02C7/12
Filed: 2005-11-28
Granted: 2011-12-20
Abstract: An internally cooled airfoil for a gas turbine engine, wherein a plurality of elongated cooling fins are provided inside the concave sidewall between two crossovers.
Patent CA-2553915-C (CA)
Inventor: NISHIYAMA HIROSHI
IPC: A61K31/501
Filed: 2005-02-02
Granted: 2010-06-01
Abstract: A drug for inhibiting vascular intimal hyperplasia which is effective in the prevention of restenosis after percutaneous transluminal coronary angioplasty (PTCA) and stent placement in a blood vessel or effective in treatments for the progress thereof. The drug for inhibiting vascular intimal hyperplasia contains either a 3(2H)-pyridazinone compound represented by the formula (I):  (wherein R1, R2, and R3 each independently represents hydrogen or C1-6 alkyl;  X represents halogeno, cyano, or hydrogen; Y represents halogeno, trifluoromethyl, or hydrogen; and A represents optionally hydroxylated C1-8 alkylene) or a pharmacologically acceptable salt thereof.
Patent CA-2554905-C (CA)
Title: Device for determining the driving capability of a driver in a vehicle
Inventor: BRAUN UWE PETER
IPC: A61B3/11
Filed: 2005-01-24
Granted: 2012-10-16
Abstract: A device is described for determining the driving capability of a driver in a vehicle which has an illumination device for illuminating at least one of the driver's eyes, a picture taking device for taking pictures of the illuminated eye, an evaluation device which serves to evaluate the pictures taken by the picture taking device, and a data storage. The device is essentially characterised in that the illumination device illuminates with flash type light or intermittently at least one of the driver's eyes, the evaluation device comparing measured values taken for the driver's pupil reaction by means of the picture taking device with at least one normal value for a pupil reaction stored in the data storage, and when the normal value is not reached by the measured values for the pupil reaction, having an effect upon a control device such that the vehicle is prevented from starting up or a vehicle in operational state is prevented from being driven on after it has stopped.
Patent CA-2555527-C (CA)
Title: Roller activation apparatus
Inventor: TSAI CHIH-HSU
IPC: G06K7/00
Filed: 2006-08-04
Granted: 2008-09-02
Abstract: A roller activation apparatus includes a switch, a roller, a light generator and a light receiver. The roller contacts the switch. A wheel of the roller has at least an opening. A wheel surface of the roller is touched to activate the switch by inputting a card. The roller rotates based on a movement of the card. The light generator is disposed at a side of the roller and is for generating a light beam. The light receiver is disposed at another side of the roller and is for receiving the light beam through the opening of the wheel so as to generate a pulse signal.  The pulse signal corresponds to the movement of the card.
Patent CA-2557115-C (CA)
Title: Azabicyclo (3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors
Inventor: ARISTA LUCA
IPC: C07D495/04
Filed: 2005-02-21
Granted: 2012-10-02
Abstract: The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein G is selected from a group consisting of: phenyl, pyridyl, benzothiazolyl, indazolyl; p is an integer ranging from 0 to 5; R1 is independently selected from a group consisting of:  halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, C1-4alkanoyl; or corresponds to a group R5; R2 is hydrogen or C1-4alkyl; R3 is C1-4alkyl; R4 is hydrogen, or a phenyl group, a heterocyclyl group, a 5- or 6-membered heteroaromatic group, or a 8- to 11-membered bicyclic group, any of which groups is optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, C1-4alkanoyl; R5 is a moiety selected from the group consisting of:  isoxazolyl, -CH2-N-pyrrolyl, 1,1-dioxido-2-isothiazolidinyl, thienyl, thiazolyl, pyridyl, 2-pyrrolidinonyl, and such a group is optionally substituted by one or two substituents selected from: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, C1-4alkanoyl; and when R1 is chlorine and p is 1, such R1 is not present in the ortho position with respect to the linking bond to the rest of the molecule; and when R1 corresponds to R5, p is 1;  processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as modulators of dopamine D3 receptors, e.g. to treat drug dependency or as antipsychotic agents.
Patent CA-2558805-C (CA)
Inventor: SMITH ROSAMUND CAROL
IPC: A61K39/395
Filed: 2005-03-17
Granted: 2011-09-27
Abstract: A neutralizing epitope is identified within amino acids 40-64 of the mature form of human myostatin. Antibodies that bind this epitope fall within the scope of the invention and may be murine, chimeric, or humanized antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammals.
Patent CA-2559400-C (CA)
Inventor: KAINER KARL ULRICH
IPC: C22C23/06
Filed: 2005-03-03
Granted: 2014-04-15
Abstract: Procédé de fabrication de profilés (16) en matière métallique légère, en particulier en matière à base de magnésium, par extrusion à l'aide d'un dispositif d'extrusion hydrostatique (10). Selon ledit procédé, un volume de matière (15) est pressé à travers une matrice (14) possédant la forme du profilé voulu (16) pour former le profilé (16). Un affineur de grain est ajouté à la matière métallique légère pour former le volume de matière (15) utilisé dans le processus d'extrusion.
Patent CA-2560814-C (CA)
Inventor: BOTROS KAMAL K
IPC: F23G7/08
Filed: 2006-09-25
Granted: 2014-08-26
Abstract: Low pressure off gases such as from dry gas seals may be recompressed to a higher pressure using multiple tandem supersonic ejectors in which upstream ejectors operate at a higher nozzle exit Mach number than down stream ejectors and all ejectors are operated at exit Mach numbers greater than 1.
Patent CA-2560886-C (CA)
Title: Synthesis of boronic ester and acid compounds
Inventor: PICKERSGILL I FRASER
IPC: C07F5/02
Filed: 2005-03-24
Granted: 2014-08-12
Abstract: The invention relates to the synthesis of boronic ester and acid compounds.  More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
Patent CA-2561622-C (CA)
Inventor: DUMBAULD PATRICK L
IPC: A61B18/12
Filed: 2006-09-29
Granted: 2015-01-20
Abstract: An endoscopic forceps includes a housing having a shaft attached thereto, the shaft including a pair of jaw members disposed at a distal end thereof. The forceps also includes a drive assembly disposed in the housing which moves the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members are closer to one another for manipulating tissue. A pair of handles is operatively connected to the drive assembly and the handles are movable relative to the housing to actuate the drive assembly to move the jaw members. Each of the jaw members is adapted to connect to a source of electrical energy such that the jaw members are capable of conducting energy for treating tissue. The forceps also includes a first switch disposed on the housing which is activatable to selectively deliver energy of a first electrical potential to at least one jaw member for treating tissue in a monopolar fashion. A second switch is disposed on the housing and is activatable to selectively deliver energy of a first electrical potential to one jaw member and selectively deliver energy of a second electrical potential to the other jaw member for treating tissue in a bipolar fashion.
Patent CA-2564090-C (CA)
Title: Backup tong with swing arms
Inventor: STUART RANDOLPH
IPC: B25B13/50
Filed: 2005-04-26
Granted: 2011-01-18
Abstract: A backup tong (10) secures the tubular against axial rotation in response to rotation by a power tong. The backup tong plate (20) supports a pair fluid powered cylinders (32, 34), and a pair of swing arms (50, 52) each pivotally connected to the respective fluid powered cylinder. A left side cam plate (44) and a right side cam plate (46) are each provided for cooperation with a respective left side and right side cam follower (58, 60). The gripping head (30) provided on the backup tong plate, and a pair of gripping heads (62, 64) are provided on a forward end of each of the swing arms for gripping the tubular. A method of the invention includes supporting the fluid powered cylinders on the backup tong plate, and pivotally connecting the swing arms to the respective fluid powered cylinders. The cam followers move within respective cam plates during actuation of the cylinders.
Patent CA-2567581-C (CA)
Inventor: JOHNSON KARL F
IPC: C12N9/24
Filed: 2005-06-01
Granted: 2016-08-09
Abstract: The present invention relates to a novel endoglycoceramidase whose hydrolytic activity has been substantially reduced or eliminated, such that the enzyme is useful for synthesis of glycolipids from a monosaccharide or oligosaccharide and a ceramide. More specifically, the endoglycoceramidase is a mutant version of a naturally occurring endoglycoceramidase, preferably comprising a mutation within the active site or the nucleophilic site of the enzyme and more preferably comprising a substitution mutation of the Glu residue within the active site or the nucleophilic site. Also disclosed are a method for generating the mutant endoglycoceramidase and a method for enzymatically synthesizing glycolipids using this mutant enzyme.
Patent CA-2567658-C (CA)
Inventor: MELARA FRANCESCANTONIO
IPC: B60B33/00
Filed: 2005-01-28
Granted: 2013-04-09
Abstract: A self-orienting caster for pieces of furniture, comprising a pair of wheels (25, 26), which are supported so that they can rotate about a horizontal axis (A) by a supporting body (2), which has a cylindrical recess (4) that has a vertical axis (B) and is open upward and axially offset with respect to said horizontal axis (A), and in which a pivot (40) for the caster (1) is inserted rotatably, the pivot being insertable in a receptacle of the piece of furniture in which the caster is to be fitted, further comprising a through seat (5) formed in the body (2), a tubular element (6) that is driven through the seat coaxially to the horizontal axis (A) and has two cylindrical tubular portions (7, 8) that lie on opposite sides of the body (2) in order to rotatably support the wheels (25, 26), means (10-18) for the axial and rotational locking of the tubular element (6) in the seat (5) and means (19-22) for retaining the wheels (25, 26) on the tubular portions (7, 8).
Patent CA-2571479-C (CA)
Title: Systeme et procede de transport de fret
Inventor: ROOP STEPHEN S
IPC: B61B1/00
Filed: 2005-05-24
Granted: 2013-11-19
Abstract: Selon un mode de réalisation de l'invention, un système de transport de fret comprend une voie présentant une paire de rails et une plaque de réaction de moteur linaire disposée entre les rails ainsi qu'un véhicule de transport présentant une baie pour conteneurs intermodale universelle conçue pour recevoir une pluralité de conteneurs. Le véhicule de transport comprend un ou plusieurs systèmes de suspension présentant chacun une pluralité de roues en acier en contact avec les rails. Le système de transport de fret comprend également un système de propulsion à induction linéaire couplé au véhicule de transport et conçu pour travailler conjointement à la plaque de réaction de moteur linéaire afin de déplacer le véhicule de transport, ainsi qu'un système de commande couplé au système de propulsion à induction linéaire et conçu pour commander le déplacement du véhicule de transport.
Patent CA-2575951-C (CA)
Inventor: MELDAHL PAUL
IPC: G01V1/38
Filed: 2005-08-03
Granted: 2013-04-09
Abstract: A method of studying a surface using an interferometer, in which there is relative motion between the surface and the interferometer, the motion having a total velocity Vtot which includes a transversal or traversing component Vt and a longitudinal component V1. The method comprises: directing an object beam of coherent light to a measurement position at the surface, whereby there is relative motion between the surface and the measurement position; arranging an array of detectors on the interferometer in a lime extending generally in the transversal direction, the detectors being arranged to detect light rays with different angular directions, representing different sensitivity directions; producing a reference beam of coherent light which is coherent with the abject beam; combining the reference beam with the reflected object beam from the surface to produce a cross interference in the speckle pattern providing information about the relative motion of the surface and the interferometer; detecting the speckle pattern and the cross interference pattern with the detectors; determining which detector in the array has zero or minimum sensitivity to the total velocity Vtot of the motion, thereby identifying the detector with a sensitivity direction line that is normal to Vtot; monitoring the temporal change in which of the detectors has zero or minimum sensitivity, thereby ascertaining the change in direction of Vtot over time, brought about by changes in V1; and determining temporal changes in V1.
Patent CA-2576326-C (CA)
Title: Motor-driven surgical cutting and fastening instrument with mechanical closure system
Inventor: SHELTON FREDERICK E IV
IPC: A61B17/285
Filed: 2007-01-26
Granted: 2014-08-26
Abstract: A surgical cutting and fastening instrument is disclosed. According to various embodiments, the instrument includes an end effector comprising an elongate channel, a clamping member pivotably connected to the channel, and a moveable cutting instrument for traversing the channel to cut an object clamped in the end effector by the clamping member when the clamping member is in a clamped position. The instrument may also comprise a main drive shaft assembly for actuating the cutting instrument in the end effector, a gear drive train connected to the main drive shaft assembly, and a motor for actuating the gear drive train. The instrument may also includes a closure trigger and a firing trigger, separate from the closure trigger, for actuating the motor when the firing trigger is retracted. Also, the instrument may comprise a mechanical closure system connected to the closure trigger and to the clamping member for causing the clamping member to pivot to the clamped position when the closure trigger is retracted.
Patent CA-2578773-C (CA)
Title: Force control strut
Inventor: ADOLINE JACK W
IPC: F16F3/04
Filed: 2007-02-16
Granted: 2010-11-23
Abstract: A force control strut comprising an elongated housing having a straight guide tube with an inner surface, a rod member having an inner end reciprocally movable along the guide tube and an outer end extending outwardly from the housing, a guide member secured into the first end of the housing to form a bushing allowing reciprocation of the rod member between a retracted position and an extended position and a bottom plug fixed to the second end of the housing. A guide piston is secured to the inner end of the rod and is slidable along the inner surface of the housing. A coil spring is located between the piston and one end of the housing to bias the rod in a given direction in the housing. There is a damper mechanism combined with the movable rod and including a plunger reciprocally mounted in an elongated force controlling passageway inside the rod. The plunger is movable outwardly from the rod and has a distal end engageable with the bottom plug to force the plunger intro the force controlling passageway to dampen movement of the rod in the housing.
Patent CA-2579367-C (CA)
Title: Reformer exercise apparatus foot bar support
Inventor: ENDELMAN KEN
IPC: A63B23/00
Filed: 2005-08-30
Granted: 2010-01-26
Abstract: A reformer exercise apparatus has a generally rectangular frame having a head end and a foot end and including a pair of spaced apart parallel track members, a movable carriage mounted on the frame for movement along the track members between said head and foot ends against one or more springs connected between the carriage and the foot end of the frame and an adjustable foot bar assembly mounted at the foot end of the frame. The foot bar assembly includes a foot bar and a foot bar support bar that fits into a pair of support brackets. Each bracket is a generally block shaped body fastened to the foot end of the frame. The bracket has a plurality of vertically spaced, downwardly opening slanted slots therein for receiving the support bar, each slanted slot having an entrance portion extending upward to an enlarged support portion at a base of the slot for retaining the support bar therein. The enlarged support portion forms a pocket to positively retain the support bar. A lock block that removably fastens to the foot bar support bar may be slidably inserted into the support portion of the bracket to lock the support bar in the support portion of the bracket.
Patent CA-2580091-C (CA)
Inventor: KELLEHER PATRICK JOSEPH
IPC: E21B43/01
Filed: 2005-09-05
Granted: 2012-07-31
Abstract: Gas monitoring apparatus associated with a remotely operated seabed system, the apparatus including a detector which is adapted so as to enable detection and/or measurement in real time the interception of shallow gas in a bore hole. In one form the gas monitoring apparatus is suitable for use with a drilling rig for drilling into a sea bed, the drilling rig including a drill string. The gas monitoring apparatus includes a housing with a collecting chamber therein for receiving drilling fluid returns which result from a drilling operation. The apparatus further includes a discharge conduit for discharging the drilling fluid returns from the collecting chamber, the collecting chamber and discharge conduit being configured so that the drilling fluid is discharged in a stratified flow which includes a predominantly dissolved gas containing phase, and if present a free gaseous phase. A gas sensor is associated with the discharge conduit and positioned so as to sense any gas in the predominantly dissolved gas containing phase and transmit the measured gas concentration signal in real-time to a surface operating station. In another form the apparatus includes a gas monitoring probe assembly suitable for use with a drilling rig for drilling into a sea bed, the gas monitoring probe assembly including a housing attachable to one end of a drill string of the rig and which includes a gas sensor having a gas sensor face within the housing.