baber/WOPTO huggingface dataset:
Patent CA-3051780-A1 (CA)
Inventor: HUQ IFTIKHAR
IPC: B03B11/00
Filed: 2019-08-12
Abstract: An extractor for non-aqueous extraction of bitumen from oil sands is provided and includes a first horizontal assembly having an upstream end and a downstream end, a liquid outlet, and an oil sands feed inlet. The first assembly is configured to provide digestion and extraction of bitumen from oil sands while advancing solids in a downstream direction, and allowing solvent diluted bitumen to separate and accumulate above the solids while flowing counter-currently with respect to the advancing solids. The extractor includes a second assembly having an upstream end fluidly connected to the downstream end of the first assembly and a downstream end, a solvent inlet and a solids discharge. The second assembly is configured to convey the solids downstream while flowing solvent from the solvent inlet in an upstream direction counter-currently with respect to the conveyed solids, thereby removing bitumen from the solids and flowing into the first assembly.
Patent CA-3056236-A1 (CA)
Inventor: COX DAVID BENJAMIN TURITZ
IPC: C12N9/22
Filed: 2018-03-15
Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting Casl3b effector protein and at least one targeting nucleic acid component like a guide RNA or crRNA.
Patent CA-3057995-A1 (CA)
Inventor: TAILLON MICHEL
IPC: F16L3/015
Filed: 2018-04-04
Abstract: L'invention concerne un ensemble support pour des conduites hydrauliques. L'ensemble support comprend un cadre conçu pour retenir au moins un anneau dans son ouverture. Chaque anneau est conçu pour être fixé autour d'un seul tuyau hydraulique, le fixant ainsi simultanément dans le cadre. Chaque anneau peut tourner par rapport au cadre autour de son axe longitudinal, ce qui réduit la contrainte exercée directement sur la conduite hydraulique. L'ensemble support comprend en outre un second cadre dans lequel le cadre est fixé. Le cadre peut tourner autour d'un axe perpendiculaire à la rotation des anneaux, afin de réduire davantage la contrainte sur les conduites hydrauliques. L'ensemble support est fixé à une machine à actionnement hydraulique au moyen d'une plaque de base ou d'une équerre sur lesquelles le second cadre est fixé à demeure.
Patent CA-3058680-A1 (CA)
Title: Closure
Inventor: SCHERER STEPHAN
IPC: B65D41/00
Filed: 2017-05-23
Abstract: A closure (1) for sealingly closing a container neck (11) having a tubular body (2) with a top wall (4), an annular side wall (5), an intermediate wall (6) joining the side wall (5) to the top wall (4) and an annular tamper evidence band (3) frangibly connected to an open end (21) described by the side wall (5). The band (3) includes retaining cams (31) protruding from its inner surface (30). Each cam (31) has a lead-in ramp (32) for engaging, in use, the flange (12) of a container neck (11) as the neck (11) is introduced into the open end (21) of the body (2) and a stop (33) for engaging the flange (12) to separate the band (3) from the body (2) when the closure (1) is subsequently removed from the neck (11). Each lead-in ramp (32) has a central recess (34) therein.
Patent CA-3060721-A1 (CA)
Title: Method of diagnosing bladder cancer.
Inventor: ZWARTHOFF ELLEN CATHARINA
IPC: C12Q1/686
Filed: 2010-04-20
Abstract: The present invention relates to a method of diagnosing cancer in a subject comprising detecting in the DNA of said subject at least one hypermethylated CpG island associated with said cancer, wherein an elevation in the level of methylation in said CpG island of said subject, relative to the level of methylation in said CpG island of a control subject, is indicative of said CpG island being hypermethylated.
Patent CA-3061277-A1 (CA)
Title: Shelf
Inventor: WEBER BERNHARD
IPC: A47B57/26
Filed: 2018-05-15
Abstract: The invention relates to a rack comprising at least one longitudinal profile (1), which can be vertically aligned, to which retaining means can be attached, into which trays, cabinet elements or other shelf elements can be inserted, which retaining means are held in clamping fashion via clamping jaws (14) on the longitudinal profile (1). The clamping jaws (14) are attached to a first plate-shaped base body (12) and to a second plate-shaped base body (13), which are arranged lying one atop the other and can be moved against each other, guided by guiding means (16), and as a result the clamping jaws (14) can be tensioned against lateral surfaces of the longitudinal profile (1). A rotation axle of an eccentric (21) for moving the clamping jaws (14) is rotatably mounted in the first plate-shaped base body (12) and the eccentric body protrudes into a recess (24) of the second plate-shaped base body (13). A simply designed retaining means is thus obtained which can be easily clamped on the longitudinal profile (1).
Patent CA-3069812-A1 (CA)
Title: Control device for operating a fire extinguisher system and extinguisher nozzle
Inventor: SAUERBIER CARSTEN
IPC: A62C31/00
Filed: 2017-07-28
Abstract: The invention relates to a control device for operating a fire extinguisher system, wherein the fire extinguisher system comprises the following: at least one hose (3) having an extinguisher nozzle (4) arranged at the end of the hose (3) and to be operated by an operator, and by means of which a pressurized extinguishing fluid can be released; a conveying pump (5) for the pressurized conveying of the extinguishing fluid in the hose (3) towards the extinguisher nozzle (4); a first supply line (7) to the conveying pump (5) from a tank (8) of a fire extinguisher device, in particular a fire extinguisher vehicle (1); and a second supply line (9) to the conveying pump (5) from a stationary extinguishing fluid source (2), and wherein the control device comprises the following: a controller (11) positioned at a distance from the extinguisher nozzle (4) and functioning as an operations center; a control line (12) running along the hose (3) into the region of the nozzle-side end of the hose (3); as well as a display (16), wherein a radio device (13) connected to the control line (12) is provided in the region of the extinguisher nozzle (4) and is capable of converting signals from the control line (12) into radio signals (15) and outputting same, a radio device (14) to be carried by the operator of the extinguisher nozzle (4) is provided, which is capable of receiving radio signals (15) output by the radio device (13); and a display (16) to be carried by the operator of the extinguisher nozzle (4) is provided, on which information based on the transmitted radio signals can be displayed.
Patent CA-3072694-A1 (CA)
Title: 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
Inventor: BECKWITH ROHAN ERIC JOHN
IPC: A61K31/4545
Filed: 2018-08-23
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein R1,R2, Rx, XI, n, nl, and q are as defined herein, methods of making and use for the treatment of IKAROS Family Zinc Finger 2 (IKZF2)-dependent diseases or disorders or where reduction of IKZF2 or IKZF4 protein levels can ameliorate a disease or disorder.
Patent CA-3077106-A1 (CA)
Title: Error detection during hybridisation of target double-stranded nucleic acid
Inventor: HAYES MATTHEW JAMES
IPC: C12Q1/6834
Filed: 2018-09-27
Abstract: A series of hybridisations is performed for forming a target double-stranded nucleic acid from initial fragments, where each further hybridisation step hybridises the direct products of a pair of earlier hybridisation steps. For at least one further hybridisation step HF, both of the corresponding pair of earlier hybridisation steps HE comprise an error-detecting type of hybridisation step, which includes an error detecting operation to detect whether the hybridised fragments formed in the error-detecting type of hybridisation step HE comprise at least one erroneous hybridised fragment, and discarding at least part of the erroneous fragment to exclude it from a subsequent further hybridisation step. By detecting and removing erroneous fragments throughout a staged and controlled hybridisation process, erroneous fragments are prevented from diluting the pool of error-free fragments at each hybridisation step, to improve yield.
Patent CA-3078134-A1 (CA)
Inventor: PARKER JONATHAN MACDONALD
IPC: B64D11/00
Filed: 2018-09-24
Abstract: An emergency vision apparatus includes a housing for attachment underneath an instrument panel in a cockpit, the housing including a front opening, a front cover for the front opening, a bottom portion of the front cover being pivotably attached to the housing to allow the front cover to open and rotate downwardly; an inflatable enclosure made of airtight material and having an expanded form when deployed and a deflated form when not in use, the enclosure when in the deflated form is stored within the housing; first and second clear members disposed at respective first and second ends of the enclosure to enable a user to see through the enclosure when expanded and observe a source of visual information at a distal end of the enclosure while smoke or other particulate matter is in the environment; a first switch operably associated with the blower to activate the blower and thereby inflate the enclosure to the expanded form when the enclosure is to be deployed; and a tubular air passageway connecting the blower and the enclosure.
Patent CA-3078657-A1 (CA)
Title: Optimized bedside safety protocol system
Inventor: HANDLER JONATHAN ALAN
IPC: G16H40/60
Filed: 2018-10-19
Abstract: Therapy device systems, modules, and methods, include memory, one or more processors, in communication with the memory, a plurality of medical therapy devices, a plurality of patient monitoring devices, and a protocol execution module, configured to execute on the one or more processors. The protocol execution module displays a plurality of protocols. The protocol execution module receives a selected protocol, associated with an individual medical therapy device being one of a plurality of medical therapy devices and associated with an individual patient monitoring device being one of a plurality of patient monitoring devices. The protocol execution module executes the selected protocol with the individual medical therapy device.
Patent CA-3079623-A1 (CA)
Inventor: POTTER MARK
IPC: A24F40/10
Filed: 2018-10-24
Abstract: A cartridge for an aerosol provision device comprises a chamber for containing a liquid from which a flow of aerosol for inhalation by a user is generated. The cartridge comprises a first connector arrangement for releasably connecting the cartridge to a body portion of the device, and a second connector arrangement for releasably connecting to a container for a material. In use, aerosol flows through the material in the container before being inhaled by the user. The first connector arrangement is configurable in a locked configuration and in an un- locked configuration, and the first connector arrangement must be configured in the un-locked configuration for the cartridge to be removeable from the body portion. The first connector arrangement is configurable from the locked configuration to the un-locked configuration while the cartridge remains stationary with respect to the body portion.
Patent CA-3080583-A1 (CA)
Inventor: FENG CAN
IPC: H05B45/37
Filed: 2020-05-08
Abstract: An electronic assembly with multi-channel outputs may include a controller and a driver.  The controller may be configured to gate m channels of outputs thereof. The driver may be configured to provide n channels of modulated signal to the controller via n wires. The n is less than m. A lighting device using the electronic assembly may further include a plurality of lighting units. The driver may include a wireless communication module to receive control signal, and the driver is configured to modulate the input DC signal based on the control signal. The n wires may be aligned along a width direction of the substrate at the end of the substrate.
Patent CA-3082076-A1 (CA)
Inventor: BRACA ALDO
IPC: B82Y5/00
Filed: 2018-11-05
Abstract: A fusion protein, a nanoparticle composed by a plurality of monomers of said fusion protein, and uses thereof. A fusion protein based on the heavy chain of human ferritin is de- scribed, which includes at the N terminus of the protein at least one metalloproteinase cleavage sequence and a modified PAS polypeptide that acts as a masking polymer that in- creases the protein drug stability, as well as a nanoparticle composed of multiple monomers of said fusion protein, a nucleic acid encoding for said fusion protein, and diagnostic and therapeutic applications thereof.
Patent CA-3082443-A1 (CA)
Title: Process for removal of biofilm
Inventor: GLASBEY TREVOR OWEN
IPC: A01N37/16
Filed: 2018-11-07
Abstract: The present invention relates to a process for removing dry surface biofilm from a surface. The process comprises: (i) dissolving a powder-based composition into water wherein the powder-based composition comprises: a) a hydrogen peroxide source, b) an acetyl donor, c) an acidifying agent, and d) a wetting agent; (ii) allowing the solution to generate a biocidally effective concentration of peracetic acid; (iii) contacting the dry surface biofilm contaminated surface with the solution of peracetic acid for a period of time; and (iv) removing the solution.
Patent CA-3083770-A1 (CA)
Inventor: MISSLING CHRISTOPHER U
IPC: A61K31/13
Filed: 2018-11-28
Abstract: A method for lowering systolic blood pressure in a patient exhibiting resistance to a antihypertensive therapy with one or more drugs, the method comprising administering to the patient ANAVEX®2-73 at a dose and frequency effective to provide a reduction of at least about 3 mmHg in one or more blood pressure parameters selected from trough sitting systolic, 24-hour ambulatory systolic, and maximum diurnal systolic blood pressures.
Patent CA-3085155-A1 (CA)
Title: Systems and methods for supplementing on-demand media
Inventor: THOMAS WILLIAM L
IPC: H04N21/858
Filed: 2001-10-09
Abstract: Systems and methods for providing supplemental content with on-demand media in an interactive television application are described.
Patent CA-3085366-A1 (CA)
Title: Derives d'aminopyridine utilises en tant qu'inhibiteurs de la phosphatidylinositol phosphate kinase
Inventor: LINDSTROM JOHAN
IPC: C07D417/14
Filed: 2018-12-21
Abstract: L'invention concerne des inhibiteurs de PI5P4K utiles dans le traitement de cancers, de maladies neurodégénératives, de troubles inflammatoires et de maladies métaboliques, ayant la formule : (I) dans laquelle, A, B, R1, X1, X2 et W sont décrits dans la description.
Patent CA-3087210-A1 (CA)
Title: Safety climb attenuation apparatus
Inventor: TURCOTTE ALLEN GASTON
IPC: A62B35/00
Filed: 2018-12-19
Abstract: A safety climb attenuation apparatus provides a more robust and visually inspectable apparatus for climbing safety. In an upper bracket, a pivot arm is attached to a base that is disposed upon a structure. The upper bracket includes an attenuation member such as an elastic bushing, mounted on the pivot arm or the base, that resists pivoting of the pivot arm relative to the base when a safety cable attached to the pivot arm causes the pivot arm to pivot. In a lower bracket, a similar attenuation member is attached to a base disposed on the structure, with an anchor bolt connecting the cable to the attenuation member so that the attenuation member resists upward movement of the cable.
Patent CA-3087261-A1 (CA)
Title: Composes benzamide
Inventor: PINCHMAN JOSEPH ROBERT
IPC: A61K31/437
Filed: 2019-01-08
Abstract: L'invention concerne des composés de formule (I). Les composés selon l'invention, ainsi que leurs sels pharmaceutiquement acceptables et des compositions de ceux-ci sont utiles pour le traitement de maladies ou d'affections, notamment d'affections caractérisées par une prolifération cellulaire excessive, telles que le cancer et des tumeurs, ainsi que des infections virales telles que le VIH.
Patent CA-3087966-A1 (CA)
Inventor: OLSON RICHARD E
IPC: C12Q1/6876
Filed: 2019-01-11
Abstract: La présente invention concerne des oligonucléotides antisens, qui ciblent l'ARNm SNCA (par exemple, au niveau d'une jonction exon/intron) dans une cellule, conduisant à une expression réduite de la protéine SNCA. La réduction de l'expression de la protéine SNCA est bénéfique pour le traitement de certains troubles médicaux, par exemple, un trouble neurologique.
Patent CA-3089407-A1 (CA)
Inventor: PASQUAL MAURIZIO FRANCESCO
IPC: F25D21/08
Filed: 2019-01-25
Abstract: L'invention concerne un appareil. L'appareil comprend un fil résistif présentant une circonférence. L'appareil comprend en outre une première couche de fibre de verre disposée autour de la circonférence du fil résistif et le long d'une longueur du fil résistif. L'appareil comprend en outre une deuxième couche de fibre de verre. L'appareil comprend en outre une troisième couche de fibre de verre, la deuxième couche de fibre de verre étant disposée entre la première couche de fibre de verre et la troisième couche de fibre de verre, la troisième couche de fibre de verre formant une couche extérieure et entourant la deuxième couche de fibre de verre.
Patent CA-3093163-A1 (CA)
Inventor: VAN DER BURG GERRIT
IPC: E02B3/26
Filed: 2019-03-06
Abstract: La présente invention concerne une défense destinée à protéger un navire d'une paroi d'amarrage, comprenant un ensemble piston et vérin hydraulique conçu de telle sorte qu'une compression de la défense soit transformée en une force pour déplacer le piston dans le vérin. Des soupapes couplent le vérin hydraulique au réservoir qui est au moins partiellement rempli de gaz. Une soupape de surpression permet à un liquide hydraulique de s'écouler du vérin au réservoir lorsque la force de compression de la défense dépasse un seuil, ce qui permet à la défense d'être comprimée. Lorsque la force s'éloigne, une soupape de retour permet à un liquide hydraulique de revenir au vérin, contraignant le piston à se déplacer pour déployer la défense, suite au mouvement du navire à l'opposé de la défense. De cette manière, le mouvement oscillant est réduit. Une pluralité de telles défenses peut être combinée avec des dispositifs de maintien de câble d'amarrage avec un mécanisme similaire qui laisse filer le câble lorsque le mouvement du navire par rapport à la paroi d'amarrage provoque l'augmentation de la force sur le câble d'amarrage. L'énergie générée à partir de telles forces peut être utilisée pour réduire le mouvement du navire.
Patent CA-3093849-A1 (CA)
Title: Vesicules extracellulaires comprenant un agoniste de sting
Inventor: JANG SU CHUL
IPC: A61K39/395
Filed: 2019-03-22
Abstract: L'invention concerne des compositions comprenant des agonistes de STING encapsulés dans EV, p. ex., un exosome, et des procédés de production des compositions décrites. L'invention concerne également des méthodes de modulation d'une réponse immunitaire par administration d'une quantité thérapeutique de EV, p. ex., exosomes encapsulant des agonistes de STING. La réponse immunitaire peut être une réponse ???ß ou une activation des cellules dendritiques myéloïdes (mDC). Des méthodes de modulation d'une réponse immunitaire qui n'induit pas d'inflammation systémique par administration d'exosomes encapsulant des agonistes de STING sont en outre décrites.
Patent CA-3094607-A1 (CA)
Inventor: AOKI SHINYA
IPC: A61L24/00
Filed: 2019-03-05
Abstract: Disclosed is a hard tissue repair composition which comprises a monomer (A), a polymer powder (B), and a polymerization initiator (C), wherein the polymer powder (B) comprises a polymer powder (B - x) with an aspect ratio of at least 1.10; and among all of the powder particles in the components included in the hard tissue repair composition, the cumulative percentage of powder particles having an aspect ratio of 1.00 to less than 1.10 is at most 75 cumulative %. Also disclosed is a hard tissue repair kit having a member that divides the monomer (A), the polymer powder (B), and the polymerization initiator (C) included in the hard tissue repair composition into at least three in a given combination and stores the same.
Patent CA-3094802-A1 (CA)
Title: Rail bolt locking device
Inventor: DAVIES IFOR C
IPC: F16B39/10
Filed: 2019-04-05
Abstract: A rail bolt nut locking device comprising a member having a first planar section at one end of the member, and a second planar section at an opposite end of the member, a central, curved intermediate section located between the planar sections. The first and second planar sections are substantially flat but include openings which are adapted to be friction fitted around the nuts of rail bolts which have been used to hold a frog or rail joint bar in place on a railway rail. The intermediate section is preferably made of a resilient plastic, to allow relative movement of the first and second planar sections. The planar sections, when fitted to the rail bolts, prevents loosening of the rail bolt nuts, and the curved intermediate section can act to prevent the rail bolts from backing out of the openings provided for the rail bolts. A device and method to lock the rail bolts in place is provided.
Patent CA-3094916-A1 (CA)
Title: Multilayer hose for an infusion set for dispensing a fluid
Inventor: MARGGI ROLF
IPC: A61M39/08
Filed: 2019-03-26
Abstract: The invention relates to a multi-layer hose (1, 1') for an infusion set for dispensing a fluid, comprising an outer layer (1a, 1a') having a polyurethane (PU) and an inner layer (1b, 1b') having a high-density polyethylene (HDPE) and/or a polypropylene (PP).
Patent CA-3097886-A1 (CA)
Inventor: JOHNSTON JENNIFER
IPC: B01D39/16
Filed: 2019-04-22
Abstract: The present disclosure relates to methods of treating cancer comprising administering Parkin ligase activator or a pharmaceutically acceptable salt thereof to a subject who has a mutant form of a protein in the Rb checkpoint pathway. The Parkin ligase activator includes triazole compounds, such as compounds of formula (I), and pharmaceutically acceptable salts thereof as disclosed herein. R1, R2, R3, M1, M2, M3, L1, L2, and L3 are as defined herein.
Patent CA-3101969-A1 (CA)
Inventor: SLACK FRANK
IPC: C12N15/11
Filed: 2019-05-30
Abstract: La présente invention concerne des matériaux et des procédés de traitement du cancer, y compris le cancer lié au virus d'Epstein-Barr.
Patent CA-3102696-A1 (CA)
Inventor: SAXBERG TOM
IPC: C09J7/22
Filed: 2019-06-07
Abstract: The invention relates to a wash-off label. According to an embodiment, the face film of the wash-off label comprises biaxially oriented plastic film and configured to shrink asymmetrically so that a difference between the shrinkage of the film in machine direction and in transverse direction is at least 55%, when exposed to washing liquid comprising caustic soda and having temperature in the range of 65-85 ºC for equal or less than 5 minutes. The invention further relates to a use of the wash-off label and to a labelled article.
Patent CA-3108596-A1 (CA)
Title: Controlling wellbore equipment using a hybrid deep generative physics neural network
Inventor: MADASU SRINATH
IPC: E21B44/00
Filed: 2021-02-12
Abstract: A system includes equipment for at least one of formation of, stimulation of, or production from a wellbore, a processor, and a non-transitory memory device. The processor is communicatively coupled to the equipment. The non-transitory memory device contains instructions executable by the processor to cause the processor to perform operations comprising training a hybrid deep generative physics neural network (HDGPNN), iteratively computing a plurality of projected values for wellbore variables using the HDGPNN, comparing the projected values to measured values, adjusting the projected values using the HDGPNN until the projected values match the measured values within a convergence criteria to produce an output value for at least one controllable parameter, and controlling the equipment by applying the output value for the at least one controllable parameter.