baber/WOPTO huggingface dataset:
Patent EA-021100-B1 (EA)
Title: Improved detection of gene expression
Inventor: OTTO GAETAN
IPC: C12Q1/68
Filed: 2010-03-17
Abstract: The invention provides an oligonucleotide, primer or probe comprising the nucleotide sequence of any of SEQ ID NO. 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 44, 61, 62 or 63. The oligonucleotide, primer or probe is useful for the detection of the methylation status of a gene. The oligonucleotides find application in the diagnosis and treatment of cancer.
Patent EA-021656-B1 (EA)
Title: Remotely controlled portable launcher for portable anti-tank missile system
Inventor: SLADKOV ALEXEY KONSTANTINOVICH
IPC: F41G5/06
Filed: 2012-01-26
Abstract: The invention relates to weapons and can be used in anti-tank missile systems. In addition to armaments, the proposed device can be used in automatic video recording systems and other systems requiring mobile exercise of azimuth and position angle coordinates. The invention proposes a remotely controlled portable launcher for a portable anti-tank missile system, which includes a support bed with a tripod, an equipment container fixed on the bed, a movable turning platform connected to the equipment contained by means of a swivel joint. A new feature is that the equipment container of the launcher includes an electronic control system containing a processor PCB, a control PCB of power follow-up drives in horizontal and vertical planes, a video capture PCB, an interface converter, a start signal shaper; the processor PCB is connected via a cable with an external network interface to a remote control panel, and with an internal bus interface to the control PCB of power follow-up drives in horizontal and vertical planes, the interface converter, the video capture PCB and the start signal shaper; the control PCB of power follow-up drives has two output channels; the control PCB of power follow-up drives is electrically connected via one channel to a power follow-up drive in a horizontal plane, and via another channel it is connected to the power follow-up drive in a vertical plane; the interface converter is connected via an internal bus interface to the control PCB of power follow-up drives and electrically connected via a separate interface to a television laser guidance instrument installed on the movable turning platform of the launcher; the video capture PCB is electrically connected to a television channel of the television laser guidance instrument; the start signal shaper is electrically connected to a mechanism for missile launching from a transporter-launcher container installed on the movable turning platform of the launcher. Technical result of the invention consists in operational remote control of the portable launcher of the portable anti-tank missile system at searching, detection and recognition of a target, measurement of distance to the target, target pointing by means of a television laser guidance instrument, at provision of missile start from the transporter-launcher container, at guidance of the missile at the target using the television laser guidance instrument. Remote control of the portable launcher at safe distance provides for safety to a gunner at execution of a combat operation by a portable anti-tank missile system.
Patent EA-028012-B1 (EA)
Title: Cyclic amine-azaheterocyclic carboxamide
Inventor: HUCK BAYARD R
IPC: C07D405/14
Filed: 2011-07-28
Abstract: The invention provides novel cyclic amine-azaheterocyclic carboxamide according to Formula (I), Formula (II) and Formula (III), wherein all the substituents are disclosed in the claims, manufacture thereof, pharmaceutical compositions comprising it and use thereof for the treatment of hyperproliferative diseases, such as cancer.
Patent EA-035397-B1 (EA)
Title: Mutated protoporphyrinogen ix oxidase (ppx) genes
Inventor: GOCAL GREGORY F W
IPC: A01H5/00
Filed: 2011-08-02
Abstract: Provided are compositions and methods relating to gene and/or protein mutations in transgenic or non-transgenic plants. In certain embodiments, the invention relates to mutations in the protoporphyrinogen IX (PPX) gene. In some embodiments the invention relates to plants that are herbicide resistant.
Patent EA-022943-B1 (EA)
Title: Trpm8 receptor antagonists
Inventor: MORICONI ALESSIO
IPC: C07D307/56
Filed: 2012-01-27
Abstract: Compounds acting as selective antagonists of Transient Receptor Potential cation channel subfamily M member 8 (hereinafter referred to as TRPM8), having formula (I), wherein R is selected from H, Br, CN, NO, SONH, SONHR' and SONR', where R' is selected from linear or branched C-Calkyl; X is selected from F, Cl, C-Calkyl, NHand OH; Y is selected from O, CH, NH and SO; R1 and R2, independently one from the other, are selected from H, F and linear or branched C-Calkyl; R3 and R4, independently one from the other, are selected from H and linear or branched C-Calkyl; Z is selected from NR6 and R6R7N, where R6 and R7 independently one from the other, are selected from H and linear or branched C-Calkyl; R5 is a residue selected from H and linear or branched C-Calkyl; Het is a heteroaryl group selected from a substituted or not substituted pyrrolyl, a substituted or not substituted N-methylpyrrolyl, a substituted or not substituted thiophenyl, a substituted or not substituted furyl and a substituted or not substituted pyridinyl. Said compounds are useful in the prevention and treatment of pathologies depending on TRPM8 activity, such as pain, inflammation, ischaemia, neurodegeneration, stroke, psychiatric disorders, inflammatory conditions and urological disorders.
Patent EA-023950-B1 (EA)
Title: Solid state forms of cabazitaxel and processes for preparation thereof
Inventor: SIMO ONDREJ
IPC: C07D305/14
Filed: 2012-04-11
Abstract: The invention relates to solid state forms of Cabazitaxel, and processes for preparation thereof via novel synthetic intermediates, and formulations comprising one or more of the solid state forms of Cabazitaxel. The present invention further provides pharmaceutical compositions comprising one or more of the solid state forms of Cabazitaxel, and methods of treating hormone-refractory prostate cancer.
Patent EA-029974-B1 (EA)
Title: Filter system for an air intake of an aircraft engine, aircraft comprising same and method of retrofitting a filter system for an air intake of an aircraft engine
Inventor: BOYCE MARK EDWARD
IPC: F02C7/052
Filed: 2012-10-10
Abstract: Aircrafts, methods, and filter systems for air intakes of aircraft engines are disclosed. One example filter system includes a filter assembly having an interior, a first end defining a bypass opening, and a second end for coupling to an air intake of an aircraft engine to permit intake air from the interior to enter the air intake. The filter assembly defines a substantially annular cross-section and includes at least one filter media for removing contaminants from intake air entering the interior through the filter media. The filter system includes a bypass closure movable relative to the filter assembly between at least a first position and a second position.
Patent EA-027058-B1 (EA)
Title: Therapeutic use of imidazopyridine derivatives
Inventor: ALCOUFFE CHANTAL
IPC: A61P35/00
Filed: 2013-01-03
Abstract: The invention relates to the use of compounds corresponding to formula (I) in which Rand Rtogether form, with the carbon atoms of the phenyl nucleus to which they are attached, a 6-membered nitrogenous heterocycle corresponding to one of the formulae (A), (B) and (C) in which the wavy lines represent the phenyl nucleus to which Rand Rare attached, or of a pharmaceutically acceptable salt thereof, for preparing a medicament for the treatment of bladder cancer.
Patent EA-027880-B1 (EA)
Title: Bace inhibitors
Inventor: GREEN STEVEN JAMES
IPC: C07D513/04
Filed: 2014-06-11
Abstract: The present invention provides a compound of Formula IIIwherein A isand Z, R, R, R, and Rare as defined herein, or a pharmaceutically acceptable salt thereof.
Patent EA-031653-B1 (EA)
Title: Method and process arrangement of separating indium and arsenic from each other
Inventor: TAKALA HEIKKI
IPC: C22B58/00
Filed: 2014-12-18
Abstract: A method and process arrangement of separating indium and arsenic from a zinc-containing starting material, comprising low acid leaching, wherein the starting material is contacted with a first leaching liquor for obtaining a first leach solution comprising in leached form a first part of arsenic and zinc, solid-liquid separation for separating solid matter from the first leach solution, high acid leaching, wherein the solid matter is contacted with a second leaching liquor for obtaining a second leach solution comprising in leached form indium and a second part of zinc and arsenic and separating and recovering indium from the second leach solution.
Patent EA-029224-B1 (EA)
Title: Bicyclic heterocyclic derivatives as bromodomain inhibitors
Inventor: ABBINENI CHANDRASEKHAR
IPC: C07D413/14
Filed: 2015-01-06
Abstract: The present invention provides bicyclic heterocyclic derivatives of formula (I), which may be therapeutically useful, more particularly as bromodomain inhibitors:wherein R, R, R, R, L, L, Cy, Cy, X, n and dotted line have the meanings given in the specification, and pharmaceutically acceptable salts or pharmaceutically acceptable stereoisomers thereof that are useful in the treatment or prevention of diseases or disorders, in particular their use in treating diseases or disorders associated with bromodomain inhibitors. The present invention also provides preparation of said compounds and pharmaceutical formulations comprising at least one of bicyclic heterocyclic derivatives of formula (I), together with a pharmaceutically acceptable carrier, diluent or excipient thereof.
Patent EA-029270-B1 (EA)
Title: Method of shaping hair
Inventor: PAUL PREM KUMAR CHEYALAZHAGAN
IPC: A61K8/27
Filed: 2015-03-30
Abstract: The present invention provides a method of shaping hair comprising the following sequential steps: (i) topically applying to dry hair a hair treatment composition comprising from 0.1 to 25wt.% dispersed zinc oxide (by weight based on the total weight of the hair treatment composition); (ii) mechanically shaping the treated hair; (iii) drying the shaped hair; (iv) washing the dried hair at least once, and (v) mechanically re-shaping the washed hair. Hair shaped with the method of the invention remains shaped even after subsequent washing. The method of the invention is also particularly suitable for damaged hair such as oxidatively treated (e.g. bleached) hair.
Patent EA-031409-B1 (EA)
Title: Indolizine derivatives as phosphoinositide 3-kinases inhibitors
Inventor: BIAGETTI MATTEO
IPC: C07D473/02
Filed: 2015-06-16
Abstract: The invention relates to compounds inhibiting phosphoinositide 3-kinases (PI3K), to pharmaceutical compositions comprising them and therapeutic use thereof in the treatment of disorders associated with PI3K enzymes.
Patent EA-038495-B1 (EA)
Title: Method for carrying out reforming
Inventor: MORTENSEN PETER MOELGAARD
Filed: 2016-03-31
Abstract: The invention relates to a method for carrying out a reaction having a hydrocarbon stream as a reactant gas and with hydrogen rich synthesis gas as reaction product, in a reformer device, where the reformer device comprises a reaction chamber, said reaction chamber comprising a semi-permeable membrane, and a heating reactor for heating the reaction chamber, wherein: a. the hydrocarbon stream is admitted into the reformer device and brought into contact with a catalyst material arranged to catalyze a steam methane reforming reaction and to catalyze a water gas shift reaction within the reaction chamber, such that b. during the reaction, CO2 passes through the semi-permeable membrane, and c. the pressure within the reaction chamber is between about 15 and about 50 bars, and wherein the temperature within the reformer device during steam reforming is below about 800°C.
Patent EA-033840-B1 (EA)
Title: Method for testing building structure under above-limit short-term dynamic stress
Inventor: ODNOKOPYLOV GEORGY IVANOVICH
IPC: G01M7/08
Filed: 2018-10-29
Abstract: The invention can be used for testing elements and structures of buildings and facilities with assessment of their survivability degree when exposed to above-limit short-term dynamic stress. The tested structure is subjected to above-limit impact force through a distribution cross-beam placed on the structure with recording the beginning and end of the action of impact force. A dynamometer is used to determine the value of the maximum dynamic stress at the moment of destroying of the building structure. Sensors are used to measure and record instantaneous values of deflections and accelerations in a fixed time interval. The obtained data is processed with the help of a measuring-computational complex. Based on the weight of building structure, distribution cross-beam and dynamometer and acceleration values, inertial forces are calculated. Based on the values of the stress acting on the test structure, its deflections and occurring inertial forces, the values of the work of forces are found at each moment in the supporting points of the distribution cross-beam. Then, the survivability level factor is determined using the formulawhere d is the time of maximum deflection of the building structure (s); b is time of the maximum outward bend of the building structure (s); A(t) are the values of the work of forces in the set time interval. The technical result is in determination of survivability level factor based on the values of the performed work over a recorded time interval and assessment of the survivability level of the tested building structure using this factor.
Patent EA-035878-B1 (EA)
Title: Triple chamber prefilled injection device
Inventor: OROFINO ERNESTO
IPC: A61M5/20
Filed: 2017-04-28
Abstract: A prefilled injection device (100) includes a tubular body (3) closed at the front by a closing element (2) and provided with a first (9) and a second (8) chambers; a first liquid substance contained in the first chamber (9); a second solid or liquid substance, contained in the second chamber (8) and intended to mix with the first substance for the reconstruction of the injectable solution. The device is characterized by comprising a front chamber (17), defined between a front plug (27) and the closing element (2), said front plug (17) being empty so that the closing element (2) is separated by the second substance. If the contact between the active substance (or second substance) and the closing element (2) is avoided, it is not necessary to carry out any stability test of the active substance with the closing element.
Patent EA-038552-B1 (EA)
Title: Process for the preparation of piperazine ring for the synthesis of pyrazinocarbazole derivatives
Inventor: DA COSTA PEREIRA ROSA CARLA PATRICIA
Filed: 2018-04-20
Abstract: The invention relates to an improved process for the synthesis of piperazine ring, particularly for the preparation of heterocyclic compounds useful as intermediates in the synthesis of pyrazinocarbazoles such as the antidepressant Pirlindole. The process described is useful to prepare Pirlindole enantiomers or a pharmaceutically acceptable salt thereof.
Patent ES-2180388-B1 (ES)
Title: Procedimiento de fabricacion de platos utilizados para los campeonatos y entrenamientos de tiro con escopeta.
Inventor: BASCO SANTAMARIA FERNANDO
IPC: C04B33/04
Filed: 2000-08-24
Granted: 2003-12-16
Abstract: Procedimiento de fabricación de platos utilizados para los campeonatos y entrenamientos de tiro con escopeta, que comprende: someter a la arcilla a un proceso de molturación en un molino de martillos con parrilla cuyo eje gira a 900 revoluciones por minuto, obteniéndose un polvo de arcilla; introducir la arcilla en una amasadora con el 16% en peso de agua cuyo eje gira a 200 revoluciones por minuto. El producto así obtenido se somete a un extrusionado en vacío a una presión de tres atmósferas consiguiéndose una lámina de 0,5 centímetros de grosor sin oclusiones de aire. Esta lámina de arcilla se somete a un conformado en una prensa a una presión de 5 Kilogramos/cm{sup,2} obteniéndose mediante moldeo los platos después de efectuar el desmoldeo por aire. Los platos se someten a un proceso de secado a una temperatura de 120º C durante 12 horas y posteriormente a una cocción en un horno a 800º C durante una hora, transcurrido este tiempo los platos se envasan posteriormente.
Patent ES-2167281-B1 (ES)
Title: Reductor de presion y procedimiento de fabricacion y aplicacion correspondientes.
Inventor: MARTIN I LLORENS JORDI
IPC: A61M5/168
Filed: 2000-11-21
Granted: 2003-06-01
Abstract: Reductor de presión y procedimiento de fabricación y aplicación correspondientes, donde el reductor de presión es para el suministro de medicamentos a un paciente, preferentemente mediante una bomba elastomérica, y es apto para permitir el suministro de un caudal nominal fijo determinado de medicamento. Comprende un primer cuerpo (1) con una primera superficie y un segundo cuerpo (3) con una segunda superficie. Una vez montados ambos cuerpos la primera superficie queda substancialmente encarada con la segunda superficie. Una de las superficies presenta un rehundido (11) de tal manera que, en la posición montada, queda conformado un conducto. El procedimiento de fabricación comprende una etapa de inyección donde se conforman directamente los rehundidos (11), o bien unas etapas de grabado, por láser o de rectificado. El molde de inyección presenta unos resaltes realizados mediante un fresado, rectificado, electroerosión, grabado por láser, o grabado por ácido.
Patent ES-2197755-B1 (ES)
Title: Sistema constructivo de redes de evacuacion de aguas.
Inventor: CORCHERO RUBIO JOSE ALBERTO
IPC: B28B21/88
Filed: 2001-05-29
Granted: 2005-03-16
Abstract: Sistema constructivo de redes de evacuación de aguas, consistente en cavar una zanja, en la que en su fondo se deposita una capa de hormigón pobre, sobre la que se extiende una manguera de material elástico y resistente, acoplada por conducciones previstas a un compresor de aire, que inyecta éste hasta conseguir presión y diámetro previsto en la manguera que forma un encofrado elástico, sobre el que se vierte hormigón hasta su recubrimiento lateral y superior en unos 5cm, incluyendo una malla electrosoldada en forma de teja sobre dicho encofrado. Una vez fraguado el hormigón, se procede al desinflado del encofrado elástico y a la retirada de éste para posterior empleo, terminando la construcción mediante el relleno con material seleccionado la zanja y cerrando ésta, quedando la canalización apta para su empleo.
Patent ES-2189648-B1 (ES)
Title: Amortiguador de vibraciones.
Inventor: GRUNDEI MANFRED
IPC: F16F9/06
Filed: 2001-06-15
Granted: 2004-10-16
Abstract: Amortiguador de vibraciones que comprende un cilindro en el que va guiado un vástago de pistón axialmente móvil, estando montados en el vástago de pistón un primer pistón estacionario y un segundo pistón axialmente desplazable en contra de una fuerza de muelle, presentando el cilindro un recinto de trabajo del lado del vástago de pistón, un recinto de trabajo alejado del vástago de pistón y un recinto de trabajo entre los dos pistones, controlando unas aberturas de paso equipadas con válvulas una unión entre los recintos de trabajo, presentando el segundo pistón en cada uno de sus dos lados al menos un muelle de recuperación y estando el pistón montado con posibilidad de desplazamiento axial en dos direcciones en contra de los muelles de recuperación.
Patent ES-2199661-B1 (ES)
Title: Calzon absorbente desechable con elasticos de pierna mejorados.
Inventor: CORONA CARLOS ALBERTO
IPC: A61F13/49
Filed: 2001-12-20
Granted: 2005-04-01
Abstract: Calzón absorbente desechable con elásticos de pierna mejorados. La presente invención se refiere a un artículo absorbente desechable, tal como un calzón absorbente desechable que tiene elásticos en las áreas de cintura y de piernas, de manera que los elásticos de las piernas rodean completamente cada una de las piernas del usuario pero no cruzan la entrepierna del mismo, eliminando de esta forma tensiones que pudieran deformar el calzón y asegurando por otro lado una completa protección y comodidad para el usuario, ya que el calzón se ajusta mejor al usuario y se evitan escurrimientos por el área de entrepierna.
Patent ES-2281215-B1 (ES)
Title: Equipo soterrado para la recogida de residuos urbanos.
Inventor: PEREZ RUEDA PEDRO
IPC: B65F1/14
Filed: 2003-10-06
Granted: 2008-08-16
Abstract: Equipo soterrado para la recogida de residuos urbanos del tipo de los que incorporan un cuerpo (2) alojado en el interior de un foso (1) excavado en el terreno, cuerpo asistido por una tapa de cierre (5), basculante, con su correspondiente acceso tubular (7) para deposición de los residuos sobre los contenedores alojados en el interior del cuerpo (2), el sistema incorpora un sensor de seguridad de pisada (15), un sensor de avería, un sensor acústico-luminoso de tapa abierta, un seguro anti-caída de la plataforma de elevación (9) y la tapa (5) y dos juegos de trincas de seguridad que evita la caída accidental de dicha plataforma (9) cuando se encuentra elevada por tareas de mantenimiento en el interior del foso, todo ello en orden a conseguir una óptima seguridad tanto para los peatones que circulan en las inmediaciones del equipo como para los operarios durante las maniobras de recogida y mantenimiento.
Patent ES-2257174-B1 (ES)
Title: Base de enchufe con obturador de seguridad y bastidor multifuncional.
Inventor: AUBERT CAPELLA JOAQUIN
IPC: H01R13/453
Filed: 2004-09-15
Granted: 2007-06-01
Abstract: Base de enchufe con obturador de seguridad y bastidor multifuncional. Base de enchufe, con obturador de seguridad situado dentro de la cubierta (2) de material dieléctrico transparente y coloreado del cuerpo base (1) y con bastidor multifuncional (3) que permite su aplicación a las configuraciones de utilización "bipolar", tipo "francés" y tipo "schuko" mediante giro de 180º sobre el eje imaginario vertical, poseyendo un sistema de embornado en el interior de dicho cuerpo base (1), para conductores eléctricos de igual o distinto diámetro (6) (6a), disponiendo los cuerpos de contacto (5) necesarios para la correcta disposición de las clavijas y correspondientes tomas de tierra en las diferentes configuraciones citadas, siendo el obturador de seguridad (9), desplazable linealmente al incidir al unísono sobre él las dos espigas de una clavija (12), venciendo la acción del resorte (10) que, al retirar dichas espigas, devolverá al obturador a su posición de cierre, poseyendo además el bastidor (3) unas pestañas verticales (32) que se introducirán en los correspondientes alojamientos (37), quedando separado del cuerpo (1) según su posición después del aludido giro de 180º y permitiendo instalar la correspondiente configuración.
Patent ES-2307347-B1 (ES)
Title: Metodo y kit para diagnosticar el riesgo de desarrollar una enfermedad trombotica venosa.
Inventor: MARTINEZ MARTINEZ ANTONIO
IPC: C12Q1/6883
Filed: 2004-10-21
Granted: 2009-09-28
Abstract: Método y kit para diagnosticar el riesgo de
desarrollar una enfermedad trombótica venosa. 
     La presente invención describe un método  in
vitro  para diagnosticar el riesgo de  padecer un evento
trombótico venoso. Este método consiste en la detección simultánea 
de cuatro alteraciones genéticas a partir de una muestra de ADN de
un individuo y  posterior análisis mediante la reacción en cadena de
la polimerasa (PCR) y ensayo  inmunoenzimático (ELISA). La invención
también describe el kit de diagnóstico para la  detección de las
alteraciones genéticas asociadas al riesgo de padecer un evento 
trombótico venoso.