baber/WOPTO huggingface dataset:
Patent CA-2368420-A1 (CA)
Inventor: GOLDSBOROUGH ANDREW
IPC: C12P19/30
Filed: 2000-03-28
Abstract: The present invention provides a method of detaching a nucleic acid molecule  from a solid support to which it is attached, wherein an unconventional nucleotide is incorporated at a pre-determined site in said nucleic acid molecule, said method comprising selectively cleaving said nucleic acid molecule at the site of said unconventional nucleotide. The nucleic acid molecule may be a chimeric molecule comprising a nucleic acid (nucleotide sequence) and another molecular component of a different chemical nature. Th is aspect of the invention also provides a chimeric molecule (or construct) comprising a nucleotide linker sequence comprising a selectively cleavable unconventional nucleotide at a pre-determined site, coupled to a functional group, which may be an affinity binding group or a reporter group. The invention finds utility in a number of applications, for example molecular biology procedures such as nucleic acid synthesis, amplification or sequencing, nucleic acid isolation or in affinity-based separation or assay procedures.
Patent CA-2368705-A1 (CA)
Title: Treatment of combustible gas streams containing hydrogen sulphide
Inventor: SCHENDEL RONALD LUDWIG
IPC: B01D5/00
Filed: 2000-04-04
Abstract: A first combustible gas stream containing hydrogen sulphide is subjected to treatment in a first Claus plant including a first thermal Claus stage. Part of the hydrogen sulphide content of a second combustible gas stream containing hydrogen sulphide is burned in at least one further thermal Claus stage. The combustion is supported by oxygen-enriched air having an oxygen mole fraction of at least about 0.25 or by oxygen. Resulting sulphur dioxide reacts with residual hydrogen sulphide to form sulphide vapour which is condensed out of the effluent gas from the further thermal Claus stage to form a sulphur-depleted effluent gas stream. A first control signal is generated which is a function of the flow rate of the second gas. A second control signal which is a function of the hydrogen sulphide/sulphur dioxide mole ratio in the sulphur-depleted effluent stream is also generated.  The control signals are employed in setting the rate at which the combustion-supporting gas is supplied to the second thermal Claus stage.
Patent CA-2371174-A1 (CA)
Title: Cyclo-alkyl substituted benzimidazoles and their use as parp inhibitors
Inventor: MULLER REINHOLD
IPC: A61P31/04
Filed: 2000-04-11
Abstract: The invention relates to a compound of formula (I) or (II), wherein A  represents a saturated or mono-unsaturated carbocycle containing 3 to 8 carbon atoms which can also have a condensed benzol ring, whereby the rings can also be substituted with one or two different or identical radicals; R1 represents hydrogen, chlorine, fluorine, bromine, iodine, branched and unbranched C1-C6-alkyl, OH, nitro, CF3, CN, NR11R12, NH-CO-R13, O-C1-C4 alkyl; and R2 represents hydrogen, branched and unbranched C1-C6 alkyl, C1-C4 alkyl-phenyl. The invention also relates to the tautomeric forms, possible enantiomeric and diastereomeric forms, possible cis-trans isomers on the rings in A and their prodrugs. The substituted benzimidazoles of general formulas (I) and (II) are inhibitors of poly(ADP-ribose) polymerase (PARP), or poly(ADP-ribose) synthase (PARS), as it is also known and can be used for the treatment or prophylaxis of diseases which are associated with the increased enzyme activity of this enzyme.
Patent CA-2372071-A1 (CA)
Title: Vehicle anchor system for juvenile vehicle seat
Inventor: KAIN JAMES M
IPC: B60N2/28
Filed: 2002-02-15
Abstract: A juvenile seat assembly is provided for use with a vehicle seat. The assembly includes a juvenile seat for placement on the vehicle seat and a vehicle anchor system coupled to the seat. The juvenile seat includes a first pair of openings and a second pair of openings. The vehicle anchor system includes an anchor belt adapted to be coupled to a pair of anchor mounts provided in or near the vehicle seat. The anchor belt includes a strap having a central portion and opposite end portions, and a connector coupled to each end portion and adapted to be coupled to one of the anchor mounts. The anchor belt is threaded through the first openings to position the seat in a first, rearwardly facing position and the anchor belt is threaded through the second openings to position the seat in a second, forwardly facing position. The vehicle anchor system also includes a leash coupled to the juvenile seat and to the central portion of the anchor belt. The leash remains coupled to the seat and to the anchor belt when the anchor belt is moved between the first and second openings of the seat.
Patent CA-2372171-A1 (CA)
Title: Benzodiazepine derivatives for imaging thrombi
Inventor: DEAN RICHARD T
IPC: C07K5/023
Filed: 2000-04-14
Abstract: The invention provides compounds comprising glycoprotein IIb/IIIa receptor-binding benzodiazepine derivatives covalently linked to metal ion chelators.  The compounds of the invention may be labeled with a radionuclide such as 99mTc and used to image thrombi.
Patent CA-2373121-A1 (CA)
Title: Vector-mediated delivery of integrating transposon sequences
Inventor: MCIVOR R SCOTT
IPC: C12N15/09
Filed: 2000-05-11
Abstract: The present invention provides non-integrating vectors, preferably non-integrating viral vectors, that include a transposon, preferably a transposon and nucleotide sequences encoding a transposase, and most preferably a transposon, nucleotide sequences encoding a transposase, and nucleotide sequences encoding a polypeptide that regulates expression of the transposase.  Also provided are methods of using the non-integrating vectors.
Patent CA-2375072-A1 (CA)
Inventor: SHABAT DORON
IPC: A61K31/365
Filed: 2000-05-24
Abstract: The present invention provides a compound that includes an active therapeutic agent attached to a blocking moiety that is sensitive to the catalytic action of molecules having retro-aldol and retro-Michael catalytic activity, methods for making such compounds and methods of converting such compounds to active therapeutic agents using molecules having aldolase activity.
Patent CA-2380054-A1 (CA)
Inventor: NEVEU DOMINIQUE
IPC: F16B7/18
Filed: 2000-05-02
Abstract: The invention concerns a modular gripper designed to transport all types of materials: metal, cardboard, glass, plastic, wood, in all types of industries. It consists of several types of aluminium sections, and several types of mechanical components made of light alloy which, by virtue of their shapes, can be quickly assembled and manage all types of materials to be transported (see photograph 1). Said invention is particular designed for gripping parts made of material of all types such as metal, cardboard, glass, plastic, wood and others in all types of industries.
Patent CA-2382533-A1 (CA)
Title: Liquefracture handpiece
Inventor: COHEN DONALD M
IPC: A61M1/00
Filed: 2000-09-18
Abstract: A surgical handpiece having two coaxial tubes or channels mounted within a body. The first tube is used for as-piration and is smaller in diameter than the second tube so as to create an annular passage between the first and second tube. The annular passage communicates with a pumping chamber formed between two electrodes. The pumping chamber works by boiling a small volume of the surgical fluid. As the fluid boils, it expands rapidly, thereby propelling the liquid downstream of the pumping chamber out of the annular passage. The distal end of the annular gap is sealed by sealing together the distal ends of the first and second tube and a plurality of orifices or ports may be formed near the seal.  As the expanding gas is propelled down the annular gap, the gas/liquid stream is forced out of the distal orifices in a controlled and directed manner.
Patent CA-2383220-A1 (CA)
Title: Controlled release pellet formulation
Inventor: MULYE NIRMAL
IPC: A61P31/04
Filed: 2000-08-30
Abstract: The present invention describes an aqueous pharmaceutical coating formulation which can be used for coating core elements containing one or more medicaments to achieve controlled release. The coated pharmaceutical formulation provides a release of medicaments in a controlled manner at highly acidic environment such as that of stomach and shows relatively faster release in media with basic pH such as that of the intestine. The coating composition is a heterogenous mixture which comprises (a) at least 75 % by weight of a water insoluble polymer which is insoluble in both acidic as well as basic pH; and (b) 1 to 25 % by weight of an enteric polymer which is substantially insoluble in water at a pH  below 4.5 and which is substantially soluble in water at a pH between above about 6.0, said enteric polymer and water insoluble polymer being present in an amount effective to control the release of said medicament. The pharmaceutical composition comprises a solid medicament present in effective amounts and the coating composition thereover.
Patent CA-2384234-A1 (CA)
Title: Long haul transmission in a dispersion managed optical communication system
Inventor: WEI XING
IPC: H04B10/516
Filed: 2002-04-29
Abstract: Phase shift keying (PSK) or differential phase shift keying (DPSK) used as the coding scheme in a high bit rate, long haul dispersion-managed optical transmission system, in which the signaling format is RZ. The system can combine multiple individual channels with different wavelengths in a WDM or dense wavelength division multiplexed (DWDM) arrangement. Dispersion management can be provided using several techniques, such as by using dispersion managed solitons, quasi-linear transmission or conventional RZ transmission with pre-compensation and post-compensation.
Patent CA-2384684-A1 (CA)
Inventor: SHE XIAO-DONG JACK
IPC: B60J3/04
Filed: 2002-03-26
Abstract: Active type sun lens and frame vehicle sunglasses is for drivers use it to effective block sun and see clear the road traffic situation, which features are: 1. The sun lens is active, install able, change able in the active type frame; include seasons sun lens, mix colours or soft chrome sun lens. 2, The frame is active, can be install or can be change active type lens. 3. Each driver can choice, install or change various prefer of colours of active type sun lens oneself, use convenience and nice-looking colours.
Patent CA-2386826-A1 (CA)
Title: Use of l-carnitine and its alkanoyl derivatives as osmotic agents in solutions for peritoneal dialysis
Inventor: ARDUINI ARDUINO
IPC: A61K31/70
Filed: 1999-10-11
Abstract: The use of L-carnitine and its alkanoyl devivatives, optionally in the form of a pharmaceutically acceptable salt, as osmotic agents in the preparation of solutions for medical use, particularly for peritoneal dialysis, is described.
Patent CA-2387122-A1 (CA)
Title: Reaction of an organic compound with a hydroperoxide
Inventor: HARDER WOLFGANG
IPC: C07D301/12
Filed: 2000-07-31
Abstract: The invention concerns a method for reacting an organic compound with a hydroperoxide using at least a heterogeneous catalyst. Said method is characterised in that the pH and the temperature of the reaction medium are modified during the reaction.
Patent CA-2388679-A1 (CA)
Inventor: BERGER HEINZ
IPC: F42B35/00
Filed: 2002-05-31
Abstract: A measuring device for measuring the concentricity of cartridges (30, 31), more particularly rifle cartridges, is essentially composed of a main body (1) provided with chambers (2) for cartridges of one or a plurality of calibers. The cartridges are radially retained in the chambers by so-called diameter compensators (9) but rotatable about their longitudinal axis. In the area of the point (39) of the projectile, an access for a measuring means (3) is provided, e.g. a dial gauge, the latter indicating the deviation of the projectile from perfect concentricity by the magnitude of its deflection variation when the cartridge (30, 31) is rotated. An aligning device (4) that is preferably also provided allows to exert a lateral pressure on the projectile in order to obtain an improved concentricity.
Patent CA-2390009-A1 (CA)
Title: Flow cell for synthesis of arrays of dna probes and the like
Inventor: GREEN ROLAND D
IPC: C12Q1/68
Filed: 2000-11-08
Abstract: A flow cell which can be used in the synthesis of DNA probes on an active surface of the substrate includes a base having a central window opening and a registration surface against which the substrate may be mounted. A gasket having a central opening defining an active area is mounted on the active surface of the substrate and has inlet and output extension openings which extend away from the central opening. A press block is engaged against the gasket to fully enclose an active volume between the press block, the peripheral walls of the central opening in the gasket, and the active surface of the substrate. A press is mounted to the base to selectively press the press block against the gasket and hold it in position.        Channels in the press block extend to the extension openings in the gasket to allow flow of reagent into and out of the active volume, which is confined to the thickness of the gasket and can thus be minimized.    The press may include a press screw which can be turned to engage against the press block to hold it into position, and which can be fumed to release the press block from the gasket, allowing rapid and easy replacement of substrates.
Patent CA-2391881-A1 (CA)
Title: Composes de transfert, leur preparation et leur utilisation
Inventor: WOHLENBERG CLAUDIA
IPC: C12N15/87
Filed: 2000-11-17
Abstract: L'invention concerne l'utilisation d'un fragment carboxy-terminal de la protéine Ki-67 ou d'une partie active, d'un fragment actif ou d'un homologue de ce dernier, en tant que composé approprié pour le transfert intracellulaire et l'absorption ou la sécrétion cellulaire. L'invention concerne en outre des composés de transfert qui contiennent l'extrémité carboxy-terminale, mentionnée ci-dessus, de la protéine Ki-67, ainsi que des vecteurs la codant. L'invention concerne en outre des compositions pharmaceutiques et l'utilisation de la protéine de transfert comme excipient ou principe actif dans le traitement de maladies.
Patent CA-2392575-A1 (CA)
Title: Inverter
Inventor: HARADA SHIN
IPC: H02M7/537
Filed: 2000-07-28
Abstract: A low-loss inverter with high switching frequency is provided using inverter elements (S1-S6), which are SiC (Silicon Carbide) JFETs.
Patent CA-2394075-A1 (CA)
Inventor: GRIFFIN JOHN
IPC: E04C2/288
Filed: 2002-07-18
Abstract: Disclosed is a panel building component, method of making same, and method of fabricating a load-bearing, insulating building wall using the panels and concrete pour after the panels are positioned on site. The panel includes at least one foam core, vertical C-studs, a channel shaped foot member in engaging relationship with the bottom edge of the foam core and the bottom end of the C-studs, two siding member's, spacers to keep the foam core centered between the siding members prior to filling the panel with concrete, and the concrete itself. The foam core and C-studs arc fabricated shorter than the finished height of the panel so that rebar steel reinforcing rods can be laid horizontally such that when the panel is filled with concrete, the top portion will be a concrete and rebar tie bean. The method of making same is simply assembly of the foregoing components, less the concrete. The method of assembling a load-bearing wall includes fixing vertical rebar to the foundation, placing a first panel building component having a top void onto a foundation between vertical rebar, orienting the panel vertically so that the vertical rebar is disposed inside outwardly facing C-studs at the edges of each panel, placing a second panel building component having a top void onto the foundation, orienting the second panel in an upright position adjacent to the first panel between vertical rebars, positioning rebar horizontally in the top void of both panels, and filling both panels with concrete.
Patent CA-2394927-A1 (CA)
Inventor: WELLMAN WADE
IPC: E04F21/24
Filed: 2002-08-05
Abstract: " In pouring concrete for slabs on grade or concrete floors, after the concrete is placed in the forms, a rake, shovel, and vibrator is used to level the concrete to be screeded."
Patent CA-2398178-A1 (CA)
Title: Cabin pressure control system, method of controlling the actual pressure inside a cabin and outflow valve
Inventor: SCHEERER FRIEDRICH-JOACHIM
IPC: B64D13/04
Filed: 2001-11-27
Abstract: The invention relates to a cabin pressure control system (10), a method of controlling the actual pressure inside a cabin (50) and an outflow valve (14; 15; 16; 17), especially for use in said system (10) or said method. The invention provides communication of actual cabin pressure to the outflow valve (14; 15; 16; 17) and additionally a common data exchange line (22) connecting the components of the cabin pressure control system (10). The system (10) is highly redundant and reliable, guarantees the desired sophisticated pressure control even if one or several components fail and allows complete elimination of the previously used fully pneumatic safety valves.
Patent CA-2398956-A1 (CA)
Inventor: SATO MOTOHIDE
IPC: A61K31/5415
Filed: 2001-02-13
Abstract: Preventives and/or remedies for postoperative stress characterized by containing CRF antagonists.
Patent CA-2399798-A1 (CA)
Title: Process for purifying a liquid hydrocarbon product
Inventor: WEBER CORNELIS EVERARDUS
IPC: B01D61/14
Filed: 2001-02-16
Abstract: Process for purifying a liquid hydrocarbon product comprising 5% by weight o r less of high molecular weight contaminants having a molecular weight of at least 1000, wherein the product stream is contacted with a hydrophobic non- porous or nano-filtration membrane and the purified product stream is recovered as the permeate. Various liquid hydrocarbon products can be treate d including process streams containing as the main product styrene, isoprene, butadiene, pentadiene, dicyclopentadiene, piperylene, C2-C5 mono-olefins or acrylates.
Patent CA-2403935-A1 (CA)
Inventor: EVANS MICHAEL JOSEPH
IPC: H01M8/04
Filed: 2001-03-26
Abstract: A fuel cell or battery for providing useful electrical power by electrochemical means, comprises: at least one cell; at least one anode and at least one cathode within said cell, and ion-conducting electrolyte means for  transporting ions between the electrodes; characterised in that: fuel, oxida nt and said electrolyte means are present as a mixture.
Patent CA-2406626-A1 (CA)
Inventor: GRUBER GERHARD
IPC: A61K35/16
Filed: 2001-04-04
Abstract: The invention relates to a method for producing a haemostatically active preparation, which contains von Willebrand factors (vWF), from a fraction of  human plasmas by chromatographically purifying a plasma fraction containing vWF on an anion exchanger material that comprises the anion exchanger groups  on graft polymeric structures (tentacle materials), by collecting a fraction  containing vWF, followed by a purification of this fraction by means of gel permeation in order to produce a purified thermostable preparation containin g vWF, and by heating the preparation in order to inactivate viruses.
Patent CA-2406650-A1 (CA)
Title: Cationic diagnostic, imaging and therapeutic agents associated with activated vascular sites
Inventor: MICHAELIS UWE
IPC: A61K47/48
Filed: 2001-05-03
Abstract: Methods and associated compositions are described for enhancing the selective delivery of therapeutic, diagnostic and imaging agents to activated vascular sites, by modifying their charge or charge density.
Patent CA-2407024-A1 (CA)
Inventor: CHEN HENG-CHIEN
IPC: H04M1/72502
Filed: 2002-10-09
Abstract: A wireless digital Key Telephone System (KTS) includes at least one extension (14a). The extension (14a) contains an audio processing circuit (70) that is electrically connected to a central processing circuit (60), a speaker (72), and a microphone (74). The audio processing circuit (70) is responsible for transmitting audio signals output from the central processing circuit (60) to the speaker (72), and transmitting audio signals received by the microphone (74) to the central processing circuit (60). The extension (14a) also contains a network controller (66), which is electrically connected to the central processing circuit (60) and to a network port (68). The network controller (66) is responsible for the transmission of network signals between the central processing circuit (60) and the network port (68).
Patent CA-2407232-A1 (CA)
Inventor: WELLINGTON SCOTT LEE
IPC: E21B43/30
Filed: 2001-04-24
Abstract: A system for heating an underground hydrocarbon containing formation, such a s a coal or shale-oil deposit, comprises an elongate electrical conductor with in a heater well traversing the formation to provide radiant heat to at least a  portion of the formation during use such that pyrolysis of hydrocarbons is initiated, which conductor is at least partly surrounded by an electrical insulation layer which comprises a granular insulating mineral material whic h layer is encased in a corrosion resistant sheath, thereby providing an inexpensive and durable electrical heater.
Patent CA-2412208-A1 (CA)
Title: Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators
Inventor: SCHROEDER RIKKE L
IPC: A61P21/00
Filed: 2001-06-14
Abstract: The present invention relates to the use of substituted 3-phenyl oxindole derivatives having general formula (I), as modulators of the potassium KCNQ  channels, to pharmaceutical compositions comprising these compounds, and to methods of treatment herewith.
Patent CA-2416314-A1 (CA)
Title: Copy protection for optical discs
Inventor: HEYLEN RICHARD A A
IPC: G11B7/26
Filed: 2001-07-26
Abstract: A method of copy protecting optical discs uses the differences in capability between the encoder associated with a laser beam recorder and that in currently available CD writers. Digital sum value (DSV) is a property of the encoded data on CDs and, in order to maintain good DSV characteristics, the encoder often has a choice of the merge bits to insert between the symbols which carry the data. An encoder, which controls a laser beam recorder may be able to choose a pattern of merge bits which result in the overall DSV having optimal properties. During mastering of a CD, data patterns are added to the disc to provide an authenticating signature. These data patterns are chosen to cause DSV problems. However, the encoder of the laser beam recorder is able to write the authenticating signature accurately to the glass master. When a CD  writer is used to make a copy of the original disc it is provided with user data from the disc, but as this user data is the product of decoding, the information about the pattern of merge bits will have been discarded.  Currently available CD writers have been found to have difficulty writing an authenticating signature of the type described without producing a resulting CD which has severe readability problems. Thus, the copy disc written by the CD writer will result in a CD reader returning corrupted data or information signalling a read error.
Patent CA-2416964-A1 (CA)
Title: Method for drilling and completing boreholes with electro-rheological fluids
Inventor: SOLIMAN MOHAMED
IPC: E21B21/08
Filed: 2003-01-22
Abstract: A method is described for using an electro-rheological fluid as a drilling and completion fluid or as a well service or fracturing fluid. By adjusting the viscosity of the fluid through application of an electrical potential to the fluid, the fluid has enhanced flexibility and multiplicity of purpose over prior art fluids.