baber/WOPTO huggingface dataset:
Patent NZ-280293-A (NZ)
Title: Crystalline forms of 2-n.butyl-3-[[2'-(tetrazol-5-yl) biphenyl-4-yl]methyl]-13-diazaspiro[4,4]non-1-en-4-one and pharmaceutical compositions
Inventor: CARON ANTOINE
IPC: C07D403/10
Filed: 1995-10-19
Abstract: Prepn. of 2-n-butyl-3-((2'-(tetrazol-5-yl)-biphenyl-4-yl)methyl)-1,3-diaza- -spiro(4.4)-non-1-ene-4-one (I) comprises: (a) treating 2-n-butyl-3-((2'-cyanobiphenyl-4-yl)methyl)-1,3-diazaspiro(4.4) non-1-ene-4-one (II) with an alkaline azide and Et3N.HCl in an inert, polar, aprotic solvent and recovering (I) in the form of an alkaline salt in aq. soln; (b) neutralising to pH 4.7-5.3, and (c) crystallising the pptd. prod. (i) in a solvent contg. < 10 vol.% water to obtain (I) in form A (i.e. (IA)) having a specified X-ray diffraction pattern; or (ii) in a solvent miscible with water contg. > 10 vol.% water to isolate (I) in form B (i.e. IB)) which has a different specified X-ray diffraction pattern. Also claimed is the prepn. of (IB) comprising recrystallising (IA) or (I) in a solvent miscible with water contg. ≥ 10% water. (IB) having a specified X-ray diffraction pattern, m.pt. 185-186 degrees C. and IR absorption at 1537,1200 and 745 cm<-1> or obtd. by the above processes is new.
Patent NZ-286251-A (NZ)
Title: Reaction injection moulding of contact lenses using mixture of oxyalkylenepolyamines, polyisocyanates and acrylic esters which forms an interpenetrating polymer network upon curing
Inventor: HILL GREGORY A
IPC: C08G18/50
Filed: 1996-03-22
Abstract: The present process is directed to making a contact lens using the RIM process.
Patent NZ-304318-A (NZ)
Title: Perfluoroalkyl ethers comprising polysiloxane and their use
Inventor: HOPKEN JENS
IPC: B05D7/24
Filed: 1996-03-22
Abstract: PCT No. PCT/EP96/01255 Sec. 371 Date Dec. 22, 1997 Sec. 102(e) Date Dec. 22, 1997 PCT Filed Mar. 22, 1996 PCT Pub. No. WO96/31791 PCT Pub. Date Oct. 10, 1996The present invention describes a free radical polymerizable segmented macromonomer based on perfluoroelkyl ether, polysiloxane and divalent organic segments. This macromoner can be polymerized and used to form moldings, contact lenses, corneal implants and other biomedical articles.
Patent NZ-335614-A (NZ)
Title: Production of patterned abrasive surfaces
Inventor: WEI PAUL
IPC: B24D3/34
Filed: 1997-12-22
Abstract: Coated abrasives suitable for very fine abrading applications can be obtained by depositing a layer of a formulation comprising abrasive grits, fillers, grinding aid, additives and a binder resin on a substrate, treating the formulation to increase the viscosity and render it plastic but non-flowing, embossing a suitable pattern on the surface of the layer, and then curing the binder component of the formulation.
Patent NZ-501719-A (NZ)
Title: Polyallylamine polymers and their use in removing bile salts
Inventor: HOLMES-FARLEY STEPHEN RANDALL
IPC: A61P9/10
Filed: 1998-06-15
Abstract: A method for removing bile salts from a hypercholesterolemic patient with a serum LDL level of at least 130 mg/dL that includes administering to the patient a therapeutically effective amount of a non-absorbable amine polymer characterised by a repeat unit having formula (1), and salts thereof, where n is a positive integer and x is zero or an integer between 1 and about 4.
Patent NZ-502448-A (NZ)
Title: Tricyclic vasopressin agonists and medicaments containing these compounds
Inventor: FAILLI AMEDEO ARTURO
IPC: C07D498/04
Filed: 1998-07-24
Abstract: Described are compounds of general formula (I): wherein W is O or NH, optionally substituted, as well as methods and pharmaceutical compositions utilising these compounds for the treatment of disorder which may be remedied or alleviated by vasopressin agonist activity, including diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, bleeding and coagulation disorders, or temporary delay of urination.
Patent NZ-502531-A (NZ)
Title: Improved fixing anchor or screw
Inventor: GLOVER FRANK
IPC: F16B25/00
Filed: 1998-07-27
Abstract: A threaded fastener (1) is disclosed for anchoring into a substrate.  The fastener or screw comprises a core portion (2) having at least one helical continuous thread provided along a substantial portion of the length of the core.  The helical thread has a V-shaped cross section defining two flanks (4a, 4b) which subtend an angle of between 60 DEG and 90 DEG.  The thread has a helix angle of between 20 DEG and 45 DEG . The crest of the thread may be flattened, and the fastener (1) is especially suited to anchoring to a masonry substrate.
Patent NZ-502822-A (NZ)
Title: Stabilized mixtures of an iodopropynyl compound and a formaldehyde donor
Inventor: LUTZ PATRICK J
IPC: A61K9/08
Filed: 1999-06-18
Abstract: A highly stable liquid formulation having broad-spectrum preservative properties which constitutes an admixture of a dialkanol-substituted dimethylhydantoin DMH (from about 20 to 95 parts), an iodopropynyl compound (0.2 to 20 parts), a stabilizer of a hydantoin, urea or derivative thereof (1 to 30 parts), and a hydroxyl solvent (0 to 60 parts). Preferably the dialkanol-substituted dimethylhydantoin is 1, 3-dimethylol-5,5-dimethylhydantoin, the iodopropynyl compound is 3-iodo-2-propynylbutyl carbamate, the stabilizer is dimethylhydantoin, and the hydroxyl solvent is propylene glycol or butylene glycol. The preservative preferably has a total formaldehyde content of 5% and less than 0.2% of free formaldehyde.
Patent NZ-503571-A (NZ)
Title: Chronic, bolus administration of D-threo methylphenidate
Inventor: DARIANI MAGHSOUD M
IPC: A61K9/54
Filed: 1998-06-17
Abstract: Chronic bolus administration of D-threo methylphenidate is provided. The administration of the D-threo isomer eliminates adverse side effects associated with the DL racemate, and provides improved effectiveness. The compositions and methods of the invention are useful in treating nervous system disorders including attention deficit disorder, attention deficit hyperactivity disorder, and cognitive decline associated with systemic diseases such as acquired immunodeficiency syndrome.
Patent NZ-504620-A (NZ)
Title: Method for operating moving hearth reducing furnace with gap being continually maintained between discharging device, typically screw, and moving hearth
Inventor: TATEISHI MASATAKA
IPC: F27D99/00
Filed: 1999-08-26
Abstract: A moving hearth reducing furnace is operated, while a gap is provided between a discharging apparatus (1) for discharging reduced iron agglomerates from the moving hearth reducing furnace and the surface of the moving hearth (2). The gap prevents squeezing metallic iron powder formed by reduction of powder included in iron oxide agglomerates into the surface of the moving hearth and the formation of an iron sheet. An iron oxide layer formed on the moving hearth (2) during the operation can be periodically scraped off without shutdown of the furnace.
Patent NZ-505881-A (NZ)
Title: IL-1 delta DNA and polypeptides
Inventor: SIMS JOHN ERNEST
IPC: G01N27/447
Filed: 1999-01-08
Abstract: DNA encoding interleukin-1 (IL-1) delta polypeptides, processes for production of recombinant forms of the polypeptides, antibodies against these polypeptides and their uses.
Patent NZ-507070-A (NZ)
Title: Method and kit for obtaining fluids and cellular material from breast ducts
Inventor: LOVE SUSAN M
IPC: A61B10/02
Filed: 1999-04-28
Abstract: Methods, kits, and apparatus for obtaining cellular, chemical, and other materials from breast ducts are described. A single milk duct is accessed and washed with a washing fluid to obtain marker materials from the lining of the duct. The washing fluid is then collected, and the marker materials in the washing fluid identified and analyzed. Usually, the washing fluid is introduced using a syringe through a lumen of a dual-lumen catheter. The ductal volume is filled with the washing fluid and excess fluid flows outwardly through a second lumen of the dual-lumen catheter, from which it is collected. Methods and kits provide for collection of fluid and cells by a lavage procedure that includes applying external pressure to the breast to improve the yield of fluid and cells from the breast duct.
Patent NZ-514540-A (NZ)
Title: Phenyl derivative useful as inhibitors of IMPDH enzyme
Inventor: STAMOS DEAN
IPC: C07C275/42
Filed: 2000-03-17
Abstract: A phenyl derivative has the formula (A) wherein: each of R1 and R2 is independently hydrogen, -CF3, alkyl, alkenyl, alkynyl, alkyl-R7, alkenyl-R7, alkynyl-R7 or -R7, provided at least one of R1 or R2 is alkyl-R7, alkenyl-R7, alkynyl-R7 or -R7; wherein up to 4 hydrogen atoms in any of the alkyl, alkenyl or alkynyl are optionally replaced by R3, or one or both of R1 or R2 are optionally esterified to form a prodrug or R1 and R2 are alternatively taken together to form tetrahydrofuranyl, when R9 is hydrogen, (R)-methyl, (R)- ethyl or (R)-hydroxymethyl, one hydrogen atom in the tetrahydrofuran is replaced by -OR6 or -R7, and when R9 is (S)- methyl, (S)-ethyl or (S)-hydroxymethyl, one hydrogen atom in the tetrahydrofuran is optionally replaced by -OR6 or -R7 or when R9 is hydrogen, (R)-methyl, (R)-ethyl or (R)- hydroxymethyl and each of R1 and R2 are independently hydrogen, unsubstituted alkyl, or unsubstituted alkenyl or alkynyl, then the portion of the compound represented by - CH(R1)R2 is a C5-12 alkyl, alkenyl or alkynyl; each R3 is independently halo, CN, -OR4, or -N(R5)2; R4, R5, R6 and R8 are as defined in the specification, each R7 is a monocyclic or bicyclic ring system wherein each ring system comprises 3 to 7 ring atoms independently selected from C, N, O and S, no more than 4 ring atoms are selected from N, O or S, any CH2 is optionally replaced with C (O) and any S is optionally replaced with S(O) or S(O)2; R9 is hydrogen, (R)-methyl, (S)-methyl, (R)-ethyl, (S)- ethyl, (R)-hydroxymethyl or (S)-hydroxymethyl; R10 is -C=N or 5-oxazolyl, and R11 is halo, -O-alkyl, or -O-alkenyl or -O-alkynyl. The compounds are useful for treating or preventing an inosine-5'-monophosphate dehydrogenase disease or condition.
Patent NZ-515339-A (NZ)
Title: Use of macrolide compounds for the treatment of dry eye
Inventor: UENO RYUJI
IPC: C07D498/18
Filed: 2000-04-26
Abstract: Disclosed is the use of the macrolide FK506 in the production of a pharmaceutical composition for the treatment of dry eye.
Patent NZ-517428-A (NZ)
Title: Improvements in image recording apparatus and method
Inventor: LOCK ROY WILLIAM
IPC: G08G1/017
Filed: 2000-09-11
Abstract: An image recording apparatus is disclosed for recording traffic signal violations such as a traffic light signal changing to a red light. The apparatus includes means for capturing a first image substantially at an instant of time that a control signal changes its status and means for storing the first image at least temporarily. The apparatus includes means for detecting presence of a vehicle or object beyond a location at which the vehicle or object is required to stop in response to the change in status and means responsive to the detecting means for recording a first image in the event that the detecting means detects presence of the vehicle or object beyond the said location. The apparatus may include means for deleting the first image in the event that the detecting means does not detect presence of the vehicle or object beyond the said location.
Patent NZ-528837-A (NZ)
Title: A bottle stopper being an arrangement of a metallic cap and an aluminium cover having a plastic cap to hold the metallic cap in place
Inventor: GARCIA OMAR ALCIDES
IPC: B65D51/18
Filed: 2003-10-10
Abstract: A bottle stopper comprises: a metallic twist off cap having an internal plastic lining to seal about the mouth of a complementary bottle when the cap is fitted to the bottle; a locking member that is fitted over the cap in use; an external cover that is fitted over the locking member in use; a first locking means that acts between the cap and the locking member to prevent relative rotation therebetween when the locking member is fitted over the cap and a second locking means that acts between the locking member and the cover to prevent relative rotation therebetween when the cover is fitted over the locking member.
Patent NZ-531605-A (NZ)
Title: A system and method for customising call alerts
Inventor: DONNELLY PETER GERALD
IPC: H04M1/724
Filed: 2002-03-28
Abstract: This method is for selecting the nature and/or form of an alert used to announce a call made by a user participating in a customised alert service. The alert service configuration for the participating user is stored on one or more network accessible devices (18) providing the necessary information for the alert descriptor. A participating user (10) operates a first communications terminal (14) to make a call to a second communications terminal (22), this call being supported by the first's communications service (24), an alert descriptor from the customised alert service configuration is then identified for the particular participating user. The second communications terminal then fetches the chosen alert descriptor from a remotely connected network device (18) and announces the call by activating an alert using the chosen alert descriptor.
Patent NZ-532027-A (NZ)
Title: Remodeling and glycoconjugation of peptides
Inventor: DE FREES SHAWN
IPC: A61P31/04
Filed: 2002-10-09
Abstract: Disclosed is a covalent conjugate between a polymeric modifying group and a glycosylated or non-glycosylated peptide, wherein said polymeric modifying group is conjugated to said peptide via an intact glycosyllinking group, wherein said glycosyllinking group is interposed between and covalently linked to both said peptide and said polymeric modifying group, wherein said covalent conjugate is formed by contacting said peptide with at least one glycosyltransferase and at least one modified sugar donor under conditions suitable for said at least one glycosyltransferase to transfer a modified sugar moiety of said at least one modified sugar donor to said peptide, thereby forming said covalent conjugate, and wherein said modified sugar moiety comprises said polymeric modifying group.
Patent NZ-536317-A (NZ)
Title: Secreted and transmembrane polypeptides and nucleic acids encoding the same
Inventor: DESNOYERS LUC
Filed: 2000-03-01
Abstract: An isolated nucleic acid that encodes a polypeptide designated PRO4356 having the amino acid sequence in Figure 22 (SEQ ID NO:50) is described. The polypeptide is capable of inducing beta-cell precursor differentiation. Preferably the nucleic acid has the sequence of Figure 21 (SEQ ID NO:49) or that deposited under ATCC accession number 203868. Also described are host cells, antibodies, vectors and methods of producing the polypeptide.
Patent NZ-538060-A (NZ)
Title: A soil additive comprising claystone , limestone , dolomite and basalt
Inventor: TREERS HUW
IPC: C09K17/04
Filed: 2003-05-26
Abstract: A soil additive produced from crushing, grinding and blending specified source rocks wherein a final product contains at least basalt, limestone, dolomite and claystone. The final product may have a modal abundance of basalt in the range of 11-91%, limestone in the range of 1-59%, dolomite in the range of 0.025-30%, and claystone. Such additives may be produced by a method of: a. conducting analysis of mineralogy and/or crystalline structure of bulk rocks to determine the applicability of the bulk rocks to be used as a limestone source rock, a basalt source rock, a dolomite source rock or a claystone source rock, b. crushing each of the source rocks identified in the analysis, c. size analysis of each of the source rocks to determine whether each source rock is of a predetermined size, d. grinding of each of the source rocks, and e. blending of the source rocks to give a final blend containing limestone, basalt, dolomite, and claystone. The soil additive assists in ecologically sustainable development, and enhance various soil types, such as by preventing leaching of desirable nutrients, or remediation of acidic or alkaline conditions. Further, the presence of the claystone reduces the negative effects of the other components, such as the greenhouse gasses produces by limestone and dolomite.
Patent NZ-540927-A (NZ)
Title: Communication system for inductive power transfer system
Inventor: TETLOW STEVEN DOUGLAS
Filed: 2005-06-22
Abstract: Methods and apparatus for communication with inductive power transfer (IPT) pick-up devices are disclosed. The IPT system (1) has a primary conductive path (2) and a number of pick-ups (3) that receive energy from current in the primary path to supply a load. An instruction is transmitted over the primary path to a pick-up, the pick-up provides a response by supplying power to the load to induce a predetermined variation in the current in the primary conductive path, and the response is determined by detecting the variation in current.
Patent NZ-545670-A (NZ)
Title: Foot for post, pole or pile
Inventor: SMITH MICHAEL ALEXANDER
Filed: 2006-03-03
Abstract: A circular fence post footing comprising a steel plate having a circular flat base and a vertical panel folded along one side of the base to form an "L" profile footing, a bendable tab formed in the side of the base opposite the panel by slots in the base, and apertures provided in each of the vertical panel, base and tab to facilitate nailing of the circular foot to the flat bottom and sides of a post. The circular foot further comprises a steel tongue pressed from the flat steel base of the foot which protrudes from the base of the vertical panel at an angle of 90 degrees. The circular foot further comprises large apertures in both the vertical and horizontal surfaces of the foot to allow the retaining material to pass through the foot and securely engage the foot. In use a 360 degree engagement with the retaining material in which the post is embedded is provided.
Patent NZ-548786-A (NZ)
Title: Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates
Inventor: STUMPF ANDREAS
IPC: C07F7/18
Filed: 2005-02-04
Abstract: Disclosed are methods for making aldehydes and ketones, wherein the methods comprise: allowing the corresponding primary or secondary alcohol to react in the presence of trichoroisocyanuric acid, a compound of formula R1SR2 and a base. In one embodiment, the alcohol is a compound of formula (I) wherein R3 is a protecting group. Also disclosed are methods for making 3-O-protected morphine dienol carboxylates comprising allowing a compound of formula (I) to oxidize in the presence of a chlorine-containing compound and a compound of formula R1SR2; and allowing the product of the oxidation step to react with an acylating agent.
Patent NZ-550527-A (NZ)
Title: Selecting Lactobacillus that increase IL-10 and decrease TGF-beta-2 in breast milk
Inventor: BJORKSTEN BENGT
IPC: A61P29/00
Filed: 2005-05-30
Abstract: Disclosed is a method for selecting a lactic acid bacterial strain for administration to a woman for increasing the level of IL-10 at the same time as decreasing the level of TGF-beta-2 in the breast milk of the woman, comprising the steps of: (a) providing a strain of Lactobacillus to a non-human test mammal; (b) isolating cells from said test mammal, (c) evaluating the level of IL-10 and the level of TGF-beta-2 in supernatants collected from said cells, wherein an increase in the level of IL-10 and a decrease in the level of TGF-beta-2 at the same time in supernatant from said test mammal compared with that from control mice identifies a lactic acid bacterial strain; and (d) selecting said lactic acid bacterial strain. Also disclosed is a method of producing a composition comprising the lactic acid bacterial strain selected in (d). The composition can be used to increase anti-inflammatory activity in a woman's breast milk.
Patent NZ-551240-A (NZ)
Title: Method for identifying PDE5-modulators
Inventor: KANACHER TOBIAS
IPC: C12N9/88
Filed: 2005-05-18
Abstract: Disclosed is a polypeptide, comprising, functionally linked: (a) the GAFA domain and GAFB domain of a human phosphodiesterase 5 (POE5) and (b) the catalytic domain of an adenylate cyclase.
Patent NZ-552946-A (NZ)
Title: Pyrazole-substituted aminoheteroaryl compounds as protein kinase inhibitors
Inventor: CUI JINGRONG JEAN
IPC: A61K31/4439
Filed: 2005-08-15
Abstract: Disclosed is a compound of the pictured formula, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, wherein R1 is an optionally substituted pyrazole, A is a substituted phenyl, and wherein the substituents are as defined in the specification. Also disclosed is the use of the compound for treating abnormal cell growth.
Patent NZ-564110-A (NZ)
Title: Formulations for alteration of biophysical properties of mucosal lining
Inventor: WATANABE WIWIK
IPC: A61K47/12
Filed: 2006-05-18
Abstract: Provided is the use of an effective amount of a calcium salt formulation for the manufacture of a medicament for increasing surface viscoelasticity of the air-liquid interface of a mucus layer at the site of administration for reducing uptake of a pathogen.
Patent NZ-565831-A (NZ)
Title: Preparation of amorphous montelukast using agitated thin film drying
Inventor: PADI PRATAP REDDY
IPC: A61K31/47
Filed: 2006-07-20
Abstract: Disclosed is a process for preparing amorphous montelukast sodium which comprises removing the solvent from a solution comprising montelukast sodium using agitated thin film drying. Also disclosed is a process for preparing amorphous montelukast sodium comprising; a) dissolving montelukast in a solvent and recrystallizing montelukast; b) reacting recrystallized montelukast with tert-butyl amine to form a salt and recovering the solid product; c) dissolving the t-butyl amine salt of montelukast in a solvent and recrystallizing the t-butyl amine salt of montelukast; d) converting a recrystallized t-butyl amine salt of montelukast in to montelukast using an acid; e) reacting the obtained montelukast with a source of sodium in a solvent; f) removing the solvent from the solution using agitated thin film dryer; and g) isolating amorphous montelukast sodium.
Patent NZ-566138-A (NZ)
Title: Stowable clothes line assembly and cover
Inventor: LEIGHTON WAYNE
IPC: D06F53/00
Filed: 2006-08-04
Abstract: A clothes line assembly including: a support; a line carrier which is adapted to have attached thereto a plurality of lines to which clothing or other articles can be secured, the line carrier being operatively mounted to the support for movement between an in-use position in which it extends laterally from the support and a non-use position; the support including a support frame which is mountable to a wall or similar structure, the line carrier being pivotally mounted to the support frame for pivotal movement between the in-use and non-use positions; and a cover arranged so that when the line carrier is in the non-use position the cover and line carrier can adopt a stowed position in which the cover can conceal the line carrier from view, and in which the cover substantially abuts the lines and/or the line carrier, wherein the cover includes a panel operatively connected to the line carrier so that in an operative position with the line carrier in the in-use position the cover is disposed above and in spaced relation from the lines on the line carrier.