baber/WOPTO huggingface dataset:
Patent CA-3066948-A1 (CA)
Title: 3-hydroxybutyrate compounds for use in reducing liver fat
Inventor: CLARKE KIERAN
IPC: A61P1/16
Filed: 2018-06-22
Abstract: The present invention provides a compound for use in reducing liver fat in a subject, wherein the compound is selected from: (i) (R)-3-hydroxybutyrate; (ii) an ester of (R)-3-hydroxybutyrate; and (iii) an oligomer obtainable by polymerising (R)-3-hydroxybutyrate moieties; or a pharmaceutically acceptable salt or solvate thereof. The compound is particularly useful in subjects suffering from a fatty liver. The compound can be used to treat non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH) or non-alcoholic fatty liver (NAFL).
Patent CA-3067072-A1 (CA)
Title: Access control method and related product
Inventor: TANG HAI
IPC: H04W74/00
Filed: 2017-06-15
Abstract: Disclosed in embodiments of the present invention are an access control method and a related product. The method comprises: a user equipment obtains access category information of an access policy for uplink access, the access category information at least comprising first access category information separately defined by an access layer AS entity; and the user equipment initiates uplink access according to the access category information. The embodiments of the present invention help to reduce reservation overheads of access policy information of an NAS layer, reduce signaling overheads between the NAS layer and an AS layer and improve the access control efficiency of a user equipment in an NR system.
Patent CA-3067326-A1 (CA)
Inventor: HICKLIN STEVEN
IPC: G06N99/00
Filed: 2018-06-18
Abstract: In some aspects, a content-extraction system can receive a query from a client device and generate a result set of digital content responsive to the query. For instance, the content-extraction system can obtain, from a search system, a set of digital content matching one or more keywords. The content-extraction system can exclude digital content items lacking core content, digital content items with duplicative content, or both. In some aspects, the content-extraction system can determine, for one or more remaining digital content items, a content attribute score. The content-extraction system can select, as the result set of digital content, a subset of digital content based on the content attribute scores. The content-extraction system can output the result set to the client device.
Patent CA-3069268-A1 (CA)
Title: Method for dehydrating alcohols to obtain olefins, involving a step of catalyst selectivation
Inventor: ARIBERT NICOLAS
IPC: C07C1/24
Filed: 2018-07-10
Abstract: The invention relates to a method for dehydrating alcohols to obtain olefins, involving a reaction step and a step of catalyst selectivation.
Patent CA-3069709-A1 (CA)
Title: Birefringent intraocular lens
Inventor: KONDIS JOHN
IPC: G02C7/02
Filed: 2018-07-30
Abstract: A multifocal intraocular lens (MF-IOL) includes a circularly birefringent material with a right- handed index of refraction n R for a light with a right-handed polarization, and a left-handed index of refraction n I, for a light with a left-handed polarization; and haptics, to position the multifocal intraocular lens inside a capsule of an eye; wherein the multifocal intraocular lens has a right-handed optical power D R for the light with the right-handed polarization, and a left-handed optical power D L for the light with the left-handed polarization, wherein D I/D R=(n L-1)(n R-1). Some variations of the MF-IOL include stimulus-orientable optically anisotropic constituents. Some classes of the MF-IOL include a self-assembling optically anisotropic compound. A corresponding method of a making a MF-IOL is comprising providing stimulus-orientable optically anisotropic constituents as part of an intraocular lens; orienting the optically anisotropic constituents by applying a non-stretching stimulus; and locking-in the oriented optically anisotropic constituents to form the multifocal intraocular lens.
Patent CA-3070288-A1 (CA)
Title: Aqueous inkjet ink sets and inkjet printing methods
Inventor: LENAERTS JENS
IPC: C09D11/324
Filed: 2018-08-16
Abstract: A pigmented aqueous inkjet ink set for manufacturing decorative panels comprising: a) a cyan aqueous inkjet ink containing a copper phthalocyanine pigment; b) a red aqueous inkjet ink containing a red pigment selected from the group consisting of C.I. Pigment Red 254, C.I. Pigment Red 122, C.I. Pigment Red 176 and mixed crystals thereof; c) a yellow aqueous inkjet ink containing a pigment C.I Pigment Yellow 150 or a mixed crystal thereof; and d) a black aqueous inkjet ink containing a carbon black pigment;  wherein the aqueous inkjet inks contain a surfactant. An inkjet printing method for manufacturing decorative panels is also disclosed.
Patent CA-3071649-A1 (CA)
Title: Systeme d'echange d'ions pour extraction de lithium
Inventor: SNYDACKER DAVID HENRY
IPC: B01D15/36
Filed: 2018-08-01
Abstract: La présente invention concerne l'extraction de lithium à partir de ressources liquides telles que des saumures naturelles et synthétiques, des solutions de lixiviat à partir d'argiles et de minéraux, et des produits recyclés.
Patent CA-3073085-A1 (CA)
Title: Cd38 modulating antibody
Inventor: GOUBIER ANNE
IPC: A61K39/395
Filed: 2018-08-16
Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD38. In particular, the present disclosure provides sequences of anti-human CD38 antibodies. Antibodies and antigen-binding portions thereof including such sequences present features compatible with pharmaceutical manufacturing and development can be provided as fully human antibodies (e.g., fully human monoclonal antibodies or antigen-binding fragments) that can be useful for medical methods and compositions, in particular for treating cancer.
Patent CA-3073585-A1 (CA)
Title: Equipment inspection apparatus
Inventor: AUDET DANIEL
IPC: G01N21/954
Filed: 2020-02-25
Abstract: An inspection apparatus configured to provide assistance in the inspection of an object such as but not limited to a petrochemical vessel or pipeline. The inspection apparatus of the present invention includes a support pole wherein the support pole has an inspection assembly mounted to the second end thereof. The inspection assembly includes a base mount having an upper mounting plate and a lower mounting plate secured to the upper surface and lower surface respectively. A plurality of light mounts are secured to the upper mounting plate and the lower mounting plate each having a light secured thereto. The inspection assembly is moveably mounted to the support pole utilizing a first arm assembly and a second arm assembly. An additional pole member having a reel assembly with a steel cable is further included to provide control and manipulation of the inspection assembly.
Patent CA-3077176-A1 (CA)
Title: Diffuser with uplight
Inventor: ZHANG YINAN
IPC: F21V7/10
Filed: 2018-09-25
Abstract: The present disclosure is directed to an apparatus. The apparatus includes a light diffusion portion comprising a same shape and approximately a same two dimensional size as a bottom surface of a light source, a light redirection device coupled to a perimeter of the light diffusion portion, wherein the light redirection device redirects a first portion of light emitted from a light source in a direction opposite a second portion of light emitted from the light source that travels through the light diffusion portion, and at least one mechanical coupling member coupled to the light redirection device, wherein the at least one mechanical coupling member is to connect to a corresponding portion of the light source.
Patent CA-3079499-A1 (CA)
Title: Dispositif d'imagerie retinienne et procedes associes
Inventor: RAFAELI OMER
IPC: A61B3/14
Filed: 2018-11-04
Abstract: La présente invention concerne des dispositifs d'imagerie ophtalmique et des procédés associés mettant en uvre l'auto-alignement d'un utilisateur avec un axe optique du dispositif d'imagerie. Un dispositif d'imagerie ophtalmique comprend un ensemble d'imagerie ayant un axe optique, un ensemble boîtier et un ensemble de visualisation. L'ensemble boîtier est conçu pour reposer sur une surface horizontale pendant le fonctionnement de l'ensemble d'imagerie. L'axe optique est orienté à un angle compris entre 45 degrés et 85 degrés par rapport à la surface horizontale. L'ensemble de visualisation comprend une surface d'interface présentant une forme lui permettant d'être en contact avec la tête d'un utilisateur afin de stabiliser une position et une orientation de la tête de l'utilisateur par rapport à l'axe optique. L'ensemble de visualisation reçoit différentes positions et/ou orientations de la tête de l'utilisateur par rapport à l'axe optique en vue de permettre l'alignement, par l'utilisateur, de l'un des yeux de l'utilisateur avec l'axe optique.
Patent CA-3080776-A1 (CA)
Title: Sanitary installation
Inventor: STAMMEL THOMAS
IPC: A47K1/00
Filed: 2020-05-13
Abstract: Sanitary installation, comprising a ceramic or porcelain wash basin or wash stand and a vanity unit, wherein the vanity unit has at least one pull-out drawer having two side walls and a front wall, wherein the shape of the side walls and of the front wall conforms to the shape of the front and side end faces of the wash basin or wash stand, wherein the end faces are aligned with the side walls and the front wall and wherein the side walls, the front wall and the end faces are coated with a veneer, applied via an adhesive bond, or with a paint.
Patent CA-3082436-A1 (CA)
Inventor: SHPALL ELIZABETH
IPC: A61K35/28
Filed: 2018-11-16
Abstract: L'invention concerne des procédés de fabrication d'exosomes de qualité clinique dérivés de cellules souches mésenchymateuses (CSM). L'invention concerne en outre des procédés de chargement des exosomes avec des agents thérapeutiques, tels que pARNi. L'invention concerne également des méthodes de traitement de maladies par administration des exosomes de qualité clinique.
Patent CA-3083005-A1 (CA)
Inventor: EBERWEIN ZACHARY
IPC: A41D13/06
Filed: 2018-12-13
Abstract: Un vêtement (200, 200', 200") de la présente invention comprend une boucle fermée pouvant être tendue (220, 220', 220") pour stabiliser un genou humain (100). La boucle est conçue pour se déplacer librement le long d'un conduit (222, 222', 222") à l'intérieur du vêtement et est pourvue d'un tendeur (240, 240', 240", 940, 290"). Le conduit se croise sur lui-même entre le côté latéral et un côté médial sur le côté antérieur de la jambe, au moins l'un au-dessus (F, F', F", Y) et l'autre en dessous (E, E', E", X) du genou pour exercer une compression sur les ligaments du genou lorsque la boucle est tendue. Le conduit encercle la jambe inférieure au niveau d'une région distale du triceps sural, réalisant ainsi un ancrage à la jambe inférieure. Un ancrage (230) est situé au niveau ou au-dessus de la cuisse. Un procédé de stabilisation du genou à l'aide de la boucle pouvant être tendue consiste à positionner le vêtement de manière à assurer que le conduit suive un trajet prédéterminé sur la jambe qui place la boucle sur au moins l'un des deux ligaments collatéraux du genou et que le tendeur est actionné pour ajuster la compression sur les ligaments.
Patent CA-3083748-A1 (CA)
Inventor: SANTAMARIA PEDRO
IPC: A61P37/06
Filed: 2018-11-28
Abstract: Described herein are compositions and methods useful for treating autoimmune diseases and inflammatory disorders. The compositions and methods utilize ubiquitous, non-tissue specific antigens associated with major histocompatibility complexes (MHCs) and coupled to a nanoparticle core to induce regulatory T cells and regulatory B cells.
Patent CA-3084266-A1 (CA)
Inventor: UNGER DARRICK DAVID
IPC: A01N65/42
Filed: 2018-12-20
Abstract: The invention relates to sabadilla alkaloid emulsifiab!e concentrate compositions. The present invention further relates to methods of controlling pests by application of sabadilla alkaloid emulsifiable concentrate compositions.
Patent CA-3086759-A1 (CA)
Title: 1, 3, 4, 5-tetrahydro-2h-pyrido[4,3-b]indole derivatives for the treatment, alleviation or prevention of disorders associated with tau aggregates like alzheimer's disease
Inventor: NAMPALLY SREENIVASACHARY
IPC: C07D471/04
Filed: 2019-01-04
Abstract: The present invention relates to compounds of formula (I) that can be employed in the treatment, alleviation or prevention of a group of disorders and abnormalities associated with Tau (Tubulin associated unit) protein aggregates including, but not limited to, Neurofibrillary Tangles (NFTs), such as Alzheimer's disease (AD)
Patent CA-3092235-A1 (CA)
Inventor: PUENTENER KURT
IPC: C07H19/167
Filed: 2019-03-12
Abstract: The invention comprises LNA-dicarboxylic acid derivatives of the formula I or salts thereof, wherein R1 is a nucleobase or a modified nucleobase R2 is a hydroxy protecting group and n is an integer from 1 to 5. The LNA-dicarboxylic acid derivatives of the formula I can be used in preloaded solid supports of the formula III and as that serve as suitable start material for oligonucleotide synthesis.
Patent CA-3094117-A1 (CA)
Inventor: RUNGE JORN
IPC: H02J3/24
Filed: 2019-02-19
Abstract: L'invention concerne un procédé réalisé par au moins un appareil comprenant : la détermination d'un facteur de correction pour au moins un premier transformateur de tension disposé dans un réseau électrique, le facteur de correction étant indicatif d'une correction pour obtenir des valeurs mesurées correctes mesurées par au moins un premier transformateur de tension. La détermination du facteur de correction de l'au moins un premier transformateur de tension est au moins partiellement basée sur une première tension mesurée d'au moins un premier transformateur de tension et une seconde tension mesurée d'au moins un premier transformateur de tension. La deuxième tension de l'au moins un premier transformateur de tension est déterminée au moins en partie sur la base d'une fonction de transfert connue d'au moins un deuxième transformateur de tension, et la première tension de l'au moins un premier transformateur de tension est déterminée sans tenir compte de la fonction de transfert connue d'au moins un deuxième transformateur de tension ; la détermination d'un facteur d'étalonnage pour l'au moins un premier transformateur de tension, au moins en partie sur la base du facteur de correction déterminé ; et la délivrance ou la provocation de la délivrance du facteur d'étalonnage déterminé. L'invention concerne en outre un dispositif conçu de manière appropriée et un système.
Patent CA-3096137-A1 (CA)
Title: Surgical staple cartridge
Inventor: ESCHBACH MATTHEW
IPC: A61B17/064
Filed: 2020-10-14
Abstract: ABSTRACT A staple cartridge is adapted to enhance cell migration towards a wound site when staples are placed in tissue. In order to enhance cell migration, the staple cartridge is adapted to create an electrical potential within the tissue in the area of a wound or cut line. In embodiments, the electrical potential is created within the tissue by using staples in spaced rows formed of dissimilar metals having different anodic indexes to create a voltage gradient in the tissue to enhance cell migration toward the cut line. Date Recue/Date Received 2020-10-14
Patent CA-3099296-A1 (CA)
Inventor: WANG CHANG YI
IPC: C07K14/005
Filed: 2019-05-03
Abstract: The present invention is directed to novel heterologous promiscuous and artificial T helper cell epitopes (Th epitopes) designed to provide optimum immunogenicity of a target antigenic site. The disclosed Th epitopes, when covalently linked to a B cell epitope in a peptide immunogen construct, elicit a strong antibody response to the B cell epitope of the target antigenic site. The Th epitopes are immunosilent on their own, i.e., little, if any, of the antibodies generated by the peptide immunogen constructs will be directed towards the Th epitope, thus allowing a very focused immune response directed to the targeted antigenic site. The heterologous promiscuous Th epitopes provide effective and safe peptide immunogens that do not generate inflammatory, anti-self, cell-mediated immune responses following administration.
Patent CA-3102888-A1 (CA)
Title: Double-layer multi-strand cord with improved penetrability
Inventor: CHEVALLEY MARIANNA
IPC: D07B1/06
Filed: 2019-06-04
Abstract: The disclosed cord (50) comprises K > 1 helically wound inner strands (TI) and L > 1 outer strands (TE). Each inner strand (TI) comprises: - an inner layer (C1) consisting of Q = 2, 3 or 4 inner wires (F1); - an intermediate layer (C2) consisting of M intermediate wires (F2) wound at a pitch p2; - an outer layer (C3) consisting of N outer wires (F3) wound at a pitch p3. The average inter-strand distance E between two adjacent outer strands is at least 30 µm. p1 is different from p2 and/or the direction of the inner layer (C1) of each inner strand (TI) is different from the direction of the intermediate layer (C2) of each inner strand (TI). The intermediate layer (C2) of each inner strand (TI) is desaturated, and the outer layer (C3) of each inner strand (TI) is desaturated. The following applies to pitches p2 and p3: 0.33 = (p3-p2)/p3 = 0.45 if Q=2; 0.35 = (p3-p2)/p3 = 0.42 if Q=3; 0.28 = (p3-p2)/p3 = 0.43 if Q=4.
Patent CA-3108101-A1 (CA)
Inventor: SALVI DOS REIS NEY ROBINSON
IPC: F16L55/28
Filed: 2019-07-30
Abstract: Il est décrit un système de revêtement pour l'intégration d'un équipement modulaire d'intervention interne dans des conduits tubulaires, ledit équipement comportant une pluralité de modules, le système de revêtement comprenant une gaine renfermant, de manière intégrée, au moins un module de la pluralité de modules et au moins une partie d'au moins un composant antérieur ou postérieur par rapport à tout module susmentionné. Le système de revêtement pour intégration selon la présente invention assure l'intégration mécanique de tout l'équipement modulaire d'intervention interne, permettant son fonctionnement à l'intérieur de conduits tubulaires de manière plus sûre, efficace et avantageuse.
Patent CA-3109379-A1 (CA)
Inventor: BHATIA SANGEETA
IPC: G16B40/00
Filed: 2019-06-07
Abstract: Methods of the disclosure provide an analytical pipeline for mapping activity in a disease-specific manner. Any of a variety of diseases or medical conditions may be mapped using the analytical pipeline. In preferred embodiments, the pipeline uses expression data (e.g., from RNA-Seq) to identify proteases that are active in disease tissue and subject to differential expression relative to normal tissue. A machine learning classifier selects a subset of the proteases that identify the disease with a threshold sensitivity and specificity, in which the subset is small enough that a corresponding set of protease substrates may be assembled into a nanoparticle activity sensor that, when administered to a patient, are cleaved in the presence of disease tissue to release detectable analytes signifying presence of the disease.
Patent CA-3109531-A1 (CA)
Title: Foams based on thermoplastic elastomers
Inventor: GUTMANN PETER
IPC: C08L75/08
Filed: 2019-09-12
Abstract: The invention relates to particle foams of thermoplastic polyurethane, a styrene polymer, and a viscosity modifier, to molded parts produced therefrom, to a method for producing the particle foams and molded parts, and to the use of the molded parts for shoe midsoles, shoe insoles, combined shoe soles, cushioning elements for shoes, bicycle saddles, bicycle tires, damping elements, paddings, mattresses, supports, handles, protective films, in components in automobile interior and exterior areas, in balls and sports equipment, or as a floor covering.
Patent CA-3110036-A1 (CA)
Inventor: THONI LOTHAR
IPC: B60B27/06
Filed: 2019-08-27
Abstract: L'invention concerne un dispositif (1) destiné à des véhicules ferroviaires et comprenant un tube d'essieu sensiblement creux (2) qui s'étend le long d'une direction longitudinale (LR) et qui se termine par un premier flasque de roue (3), et un support de roue (5) qui s'étend dans la direction opposée à la direction longitudinale (LR) et qui comprend un palier de roue (5), un deuxième flasque de roue (6) et un mandrin (7) de forme conique. Le deuxième flasque de roue (6), le premier flasque de roue (3) et une roue intermédiaire (8) pourvu d'un moyeu de roue (9) sont reliés entre eux par une liaison par flasque et le mandrin (7) de forme conique du support de roue (4) s'insère par complémentarité de formes à l'espace intérieur du tube d'essieu (2) à travers à travers le moyeu de roue (9) de la roue (8) dans la direction opposée à la direction longitudinale (LR) et se termine au niveau de l'élément de fixation (11), moulé et disposé dans le tube d'essieu (2), et est relié à cet élément de fixation.
Patent CA-3114590-A1 (CA)
Inventor: CIMARRA MAURIZIO
IPC: F24C15/20
Filed: 2019-10-09
Abstract: A fume extractor hood (1) comprises a frame (2) configured to at least partially fit into a receptacle (100) formed in a ceiling (101); at least one lock member (9) located at one side (3a, 3b) of the frame (2), and comprising a deployable portion (10), adapted to be alternated between a deployed configuration in which it holds the frame (2) in the receptacle (100) and a retracted configuration in which it is entirely pulled back inside a perimeter of the frame (2) to allow the frame to be moved into and out of the receptacle (100), the lock member (9) comprises at least one elastic element (11) associated with the deployable portion (10) to bias it from the retracted configuration to the deployed configuration; the lock member (9) comprises a grip element (15) connected to the deployable portion (10) and arranged to be accessible when the frame (2) fits in the receptacle (100), the grip element (15) is able to move along a center axis (V) perpendicular to the sides (3a, 3b) of the frame, the grip element is adapted to be actuated to pull the deployable portion (10) back from the deployed configuration to the retracted configuration.
Patent CA-3115804-A1 (CA)
Inventor: ENNISHI DAISUKE
IPC: A61K31/475
Filed: 2019-10-15
Abstract: The present invention relates to gene expression profiles for B-cell lymphoma. More specifically, the present invention relates to gene expression profiles for diagnosis, prognosis or therapy selection for an aggressive B-cell lymphoma.
Patent CA-3117585-A1 (CA)
Inventor: SUN JING
IPC: H04W72/04
Filed: 2019-11-13
Abstract: A user equipment (UE) may receiving, from a base station, a synchronization signal block (SSB) of a set of quasi-collocated (QCL) SSBs, the SSB comprising an indication of a parameter indicating information associated with a plurality of downlink control channel locations corresponding to the set of QCL SSBs. The UE may determine, based at least in part on the parameter, the plurality of downlink control channel locations corresponding to the set of QCL SSBs. The UE may receive a downlink grant for a system information based at least in part on monitoring one or more downlink control channel locations of the plurality of downlink control channel locations. The UE may receive the system information based at least in part on the downlink grant. The UE may establish a connection with the base station based at least in part on the SSB and the received system information.
Patent CA-3118622-A1 (CA)
Title: A tube assembly for a gas turbine engine
Inventor: MISKIE RYAN
IPC: F01D9/06
Filed: 2021-05-14
Abstract: A tube assembly for a gas turbine engine includes a rigid tube having first and second ends for connection to first port and second ports on the gas turbine engine. The first and second ports have different orientations providing for different installation vectors. The tube assembly further includes a tube adapter adjustably connected to the second port and a coupling, which, is, in turn, adjustably mounted to a distal end of the tube adapter for connection with the second end of the tube.