baber/WOPTO huggingface dataset:
Patent JP-H0561307-B2 (JP)
Inventor: RII TEIMOSHII CHAARUZU FUIRITS
IPC: C08L81/04
Filed: 1990-01-02
Abstract: A method of manufacturing a polysulphide polymer, in particular for use as a sealant in the construction industry and the like. A liquid polysulphide prepolymer is partially cured with an oxidizing curing agent such as calcium peroxide, by adding a controlled amount of water. As the cure reaches the end of its induction stage, before the viscosity rises substantially, the reaction is stopped by dehydrating with a desiccant. This gives a stable liquid prepolymer which can later be cured without an induction period by exposure to moisture and optionally a further curative.
Patent JP-2846018-B2 (JP)
IPC: C12Q1/68
Filed: 1989-01-12
Granted: 1999-01-13
Abstract: The present invention is directed to improved methods for assaying specific nucleic acid sequences in a test sample and the reagents for carrying out the methods. In the general, the methods of the invention involve the synthesis of a double-stranded nucleic acid containing the nucleic acid sequence to be detected and a promoter, the synthesis of a multiplicity of RNA transcripts under the control of the promoter, and the detection of the specific RNA transcripts produced.
Patent JP-3559042-B2 (JP)
IPC: A23K20/189
Filed: 1994-06-16
Granted: 2004-08-25
Abstract: PCT No. PCT/DK94/00237 Sec. 371 Date Nov. 28, 1995 Sec. 102(e) Date Nov. 28, 1995 PCT Filed Jun. 16, 1994 PCT Pub. No. WO95/00121 PCT Pub. Date Jan. 5, 1995This invention relates to a directly compressible enzyme powder produced by mixing a liquid enzyme preparation with a suitable carrier, using the principle of wet granulation, whereby the step of freeze drying and spray-drying is avoided. The resulting enzyme powder has extraordinary good compression qualities and may directly be tabletted.
Patent JP-3381035-B2 (JP)
IPC: B29C41/04
Filed: 1994-06-13
Granted: 2003-02-24
Abstract: For the manufacture of substantially hollow-cylindrical castings (5), especially leading-in insulators for conductors under high voltage, a more or less liquid casting material (50) is introduced into a substantially hollow-cylindrical casting mould (2) that is driven in rotation. Before the introduction of the casting material, the casting mould is heated to a temperature above the gelling temperature of the casting material. The casting mould (2) filled with casting material (50) is driven in rotation until a casting (5) that is substantially set solid has been formed. The casting so formed is then removed from the casting mould. Before the introduction of the casting material into the casting mould, however, a substantially hollow-cylindrical mesh fabric (1) is introduced into the heated casting mould (2) concentrically to the axis of rotation (22) thereof, and only then is the casting material (50) introduced into the casting mould (2).
Patent JP-3058697-B2 (JP)
IPC: B62M3/00
Filed: 1996-06-19
Granted: 2000-07-04
Abstract: A crank-rod (20) of a bicycle can make a pushing force against a pedal (24) to be more effectively converted to a rotary force against a sprocket wheel (26) and, subsequently, a rear wheel of the bicycle, although the pedal is positioned between the positions of 90 DEG  and 45 DEG  where a rider can very forcefully step on the pedal (24) in a very comfortable position. The crank-rod (20) comprises a pedal-shaft fixing hole (21) at one end, a crank-shaft fixing hole (23) at the other end and a transmitting member (22) between the pedal-shaft fixing hole (21) and the crank-shaft fixing hole (23), in which the transmitting member (22) consists of a first portion (22a) constituting a main portion of the transmitting member (22) and a second portion (22b) operating as an arm for offsetting a longitudinal axis (A) of the first portion (22a) by an offset angle  theta  from a straight line passing through the centers of the pedal-shaft fixing hole (21) and the crank-shaft fixing hole (23), the transmitting member (22) being deformed to bend by maximum amount within an extent which does not exceed an elastic limit by a force applied during running the bicycle against the free end (FE) of the first portion (22a) in a direction perpendicular to the first portion (22a) and parallel with the second portion (22b).
Patent JP-2505268-B2 (JP)
IPC: C12N15/12
Filed: 1988-07-22
Granted: 1996-06-05
Abstract: The invention provides expression vectors containing the promoter, enhancer and substantially complete 5'-untranslated region including the first intron of the major immediate early gene of human cytomegalovirus. Further vectors including the hCMV-MIE DNA linked directly to the coding sequence of a heterologous gene are described, Host cells transfected with the vectors and a process for producing heterologous polypeptides using the vectors and the use of the hCMV-MIE DNA for expression of a heterologous gene are also included within the invention.
Patent JP-2868260-B2 (JP)
IPC: G06F15/78
Filed: 1989-06-12
Granted: 1999-03-10
Abstract: A system for scheduling instruction issuance in a vector register computer achieves increased efficiency of operation by performing pre-issuance checks to determine if resources requested by the instruction will be available when the instruction issues. A decoding apparatus first determines particular resources requested by the instruction, which includes apparatus for decoding vector register requests, functional unit requests, and address and scalar register path requests. Following decoding, a conflict resolution apparatus checks resource reservation flags to determine if the requested resources will be available when the instruction issues. If any requested resources will be busy, the system issues a primary conflict signal. At the scheduled instruction issuance time, the system again checks the resource reservation flags in response to the primary conflict signal. If the requested resources are still busy, the system generates a secondary conflict signal for as long as the requested resources remain busy. Finally, when the instruction issues, the system sets the resource reservation flags to reserve the requested resources for the instruction.
Patent JP-3953103-B2 (JP)
IPC: G06T7/66
Filed: 1996-07-26
Granted: 2007-08-08
Abstract: PCT No. PCT/EP96/03308 Sec. 371 Date Feb. 3, 1998 Sec. 102(e) Date Feb. 3, 1998 PCT Filed Jul. 26, 1996 PCT Pub. No. WO97/06409 PCT Pub. Date Feb. 20, 1997The invention relates to a process and device for the rapid detection of the position of a target marking. The target marking is picked-up by imaging optics and a local opto-electronic detector of a theodolite or tachymeter. Electric signals from the detector are rapidly evaluated in a pre-processing unit by formation of sum functions for determining coordinates of the target marking in such a way that the target marking is immediately automatically detected in coarse targeting and its further movement can be followed automatically. Its track data can simultaneously be recorded.
Patent JP-4222629-B2 (JP)
IPC: A61K38/18
Filed: 1996-08-27
Granted: 2009-02-12
Abstract: A novel growth factor, neurturin, is disclosed and the human and mouse amino acid sequences are identified. Human and mouse neurturin genomic DNA sequences have been cloned and sequenced and the respective cDNA sequences identified. The subcloning into vectors and the preparation of cells stably transformed with the vectors are also disclosed. In addition, methods for treating degenerative conditions, tumor cells and obesity; methods for detecting gene alterations and methods for detecting and monitoring patient levels of neurturin are provided. Methods for identifying additional members of the neurturin-GDNF family of growth factors are also provided.
Patent JP-2968335-B2 (JP)
IPC: G02F1/015
Filed: 1990-09-04
Granted: 1999-10-25
Abstract: By forming quantum well (QW) structures with two different heterojunctions having different band offsets it is possible to form QWs having built-in dipoles. The presence of a built-in dipole in a narrow enough well results in QWs having absorption edges which, unlike those of conventional QWs, can be shifted to the blue by application of an electric field of appropriate polarity.
Patent JP-2895231-B2 (JP)
IPC: C11D1/28
Filed: 1993-01-29
Granted: 1999-05-24
Abstract: Liquid compositions comprising acyloxy alkane sulfonic acid salt, paraffin, water, optional salt reactant, and optional fatty acid are provided which have improved stability and pumpability. Also a method of preparing and a method of storing these composition are provided utilizing temperature and particle size limitations. The composition, method of making, and method of storing the composition provide improved storage stability, pumpability, and a decrease in processing time for the incorporation of the composition into finished bar formulations.
Patent JP-3601834-B2 (JP)
IPC: H01J49/04
Filed: 1997-09-19
Granted: 2004-12-15
Abstract: Matrix assisted laser desorption/ionization is performed in a manner to thermalize large analyte ions in a plume of desorbed material for spectroscopic analysis. The thermalized ions have a low or zero mean velocity and are presented at a well-defined instant in time, reducing artifacts and sharpening the spectral peaks. In one embodiment the light is delivered to a matrix or sample holder having a cover, baffle or compartment. The baffle or compartment impedes or contains a plume of desorbed material and the analyte undergoes collisions to lower its mean velocity and directionality. Thus "thermalized" the analyte ions are passed to a mass analysis instrument. In a preferred embodiment an optical fiber butts up against a thin transparent plate on which the specimen resides, with the matrix side in a vacuum acceleration chamber. A mechanical stage moves the specimen in both the x- and y- directions to select a point on the specimen which is to receive the radiation. The use of a fiber optic illuminator allows the entire stage assembly to be subsumed essentially within the dimensions of a conventional stage. In other embodiments, a thermalizing compartment is provided in a capillary tube about the end of the illumination fiber and the sample matrix is deposited along the inner cylindrical wall of the tube, so the capillary forms a migration path to the outlet for thermalization of the desorbed analyte. In other embodiments microstructures having the shape of a small lean-to, overhang or perforated cover plate, or providing a high aspect surface texture, provide the necessary containment to promote thermalization of the released analyte. A thin layer or cover of fibrous or permeable material may also be used to thermalize the analyte before mass analysis, and in another embodiment this material may also act as the substrate. An automated instrument may include a fixed array of illumination fibers which are illuminated at different times to eject samples from a corresponding array of points on the specimen.
Patent JP-2908019-B2 (JP)
Inventor: CAPEL IFOR DONALD
IPC: A61H39/00
Filed: 1990-10-31
Granted: 1999-06-21
Abstract: PCT No. PCT/GB90/01670 Sec. 371 Date Jun. 15, 1992 Sec. 102(e) Date Jun. 15, 1992 PCT Filed Oct. 31, 1990 PCT Pub. No. WO91/06340 PCT Pub. Date May 16, 1991.An electrode for providing TCET, especially via the earlobes of the patient, comprises an electrical conductor for application to the skin, connected to a lead for supplying the TCET signal from a signal generating device, characterized in that the conductor comprises a generally conical needle point capable of penetrating the epidermis so as to provide good electrical contact over a very small area. The electrode can be used in the impedance of less than 100 k OMEGA ; and with apparatus for generating an electrical signal for use in TCET, adapted to provide a signal at a current of less than 200  mu A (0.2 mA), especially when adapted to provide an AC signal in which each positive pulse is relatively short and high without being spiked and the following negative pulse is relatively wide and low, the total amount of positive and negative charge being balanced. Methods of providing TCET treatment to patients using the electrode and apparatus are also provided.
Patent JP-4148533-B2 (JP)
IPC: A61K39/395
Filed: 1996-03-29
Granted: 2008-09-10
Abstract: The present invention provides a method for treating the inflammatory response of an established colitis in a subject with inflammatory bowel disease (IBD), comprising administering to a subject diagnosed with an established colitis from an IBD an amount of an antibody to interleukin-12 effective in reducing the colitis-inducing effect of interleukin-12. Also provided is a method for screening a substance for its effectiveness in reducing the inflammatory response of an established colitis comprising obtaining an animal having an established colitis; administering the substance to an animal; and assaying the animal for an effect on interleukin-12 which results in the reduction of the inflammatory response of the colitis, an amount of reduction of the inflammatory response greater than the amount of reduction produced by the administration of antibodies against interferon-gamma or tumor necrosis factor-alpha indicating an effective substance. Additionally, the present invention provides a method for screening a substance for its effectiveness in preventing inflammatory bowel disease comprising administering the substance to an animal susceptible to colitis; subjecting the animal to a treatment that will induce a colitis; assaying the animal for the development of a colitis; and comparing the effectiveness of the substance in preventing development of a colitis to the effectiveness of antibodies to interferon-gamma or tumor necrosis factor-alpha in preventing development of a colitis, a substance more effective in preventing the development of a colitis than antibodies to interferon-gamma or tumor necrosis factor-alpha indicating an effective substance.
Patent JP-2969179-B2 (JP)
IPC: A61K8/00
Filed: 1995-12-07
Granted: 1999-11-02
Abstract: PCT No. PCT/DE95/01745 Sec. 371 Date Jun. 6, 1997 Sec. 102(e) Date Jun. 6, 1997 PCT Filed Dec. 7, 1995 PCT Pub. No. WO96/17584 PCT Pub. Date Jun. 13, 1996A combination preparation for stimulating the growth of hair and, optionally, the growth of skin and nails with a combination of active ingredients comprising vitamins, enzymes, and amino acids develops its effects from within the body, in that the combination of active ingredients of the combination preparation is made as a component of a form of oral administration, and that it comprises at least: 1.25 wt. % provitamin A; 0.27 wt. % vitamin B1; 5.25 wt. % vitamins of the B2 group; 0.37 wt. % vitamin B6; 0.001 wt. % vitamin B12; 15.61 wt. % vitamin C; 2.5 wt. % vitamin E; 1.04 wt. % coenzyme Q 10; 0.02 wt. % methionine; and 0.018 wt. % cystine. To increase the effectiveness of the combination preparation, its use is described as a supplement to a topically applicable hair growth stimulant, in particular a thymus-containing therapeutical agent.
Patent JP-3213320-B2 (JP)
IPC: D21C5/02
Filed: 1993-04-14
Granted: 2001-10-02
Abstract: A process of de-inking waste paper can be operated under conditions using a simple combination of chemicals to result in a waste liquor that is substantially environmentally friendly. The process comprises forming a pulp from the waste paper in an aqueous medium that has a pH of between 6 and 9 and that is substantially free of dissolved phosphate and that includes an ink-dispersing amount of dispersing agent, and separating the ink from the pulp.
Patent JP-2809882-B2 (JP)
IPC: A47J36/02
Filed: 1994-01-21
Granted: 1998-10-15
Abstract: The process uses a perforated sheet (3) of a hard metal (4). Each hole (6) in this is made with a lip (5) whose end (7) projects towards the surface of the metal (1) to which it is to be added. The lips form an angle (A) with the surface of the sheet and their ends are perpendicular to the plane of the sheet (D). The sheet is pressed on to the surface of the softer metal so that the lips straighten and the metal creeps into the holes to anchor the sheet. <IMAGE>
Patent JP-2774382-B2 (JP)
IPC: G02C5/12
Filed: 1995-01-11
Granted: 1998-07-09
Abstract: A retainer for securing a nose pad on an eyeglasses frame, the retainer being composed of a flat, one-piece pad arm having a receiving opening in the form of an elongated hole, and a retaining element of plastic secured to the nose pad, the retaining element having a constriction and being receivable in the receiving opening of the pad arm to be locked in the receiving opening by engagement of the constriction in the opening. The pad arm is a bilaterally symmetrical structure having a first end in which the opening is formed, is made of material which extends continuously around the opening and is substantially inelastic around the opening. The opening cross section of the elongated hole is selected and the retaining element is formed such that when the constriction engages in the receiving opening, a transition surface of the retaining element is engageable with the pad arm for allowing the retaining element and the nose pad to be pivotable and tiltable relative to the pad arm.
Patent JP-3621420-B2 (JP)
IPC: G11B17/22
Filed: 1996-01-03
Granted: 2005-02-16
Abstract: The storage unit (90) has at least one storage device for holding data carriers, a read/write station (106) for the data carriers and a gripping and transfer device (92,102) for transferring individual data carriers (34) between the storage device and read/write station. Each storage device consists of a number of stacked carrier plates carried on a vertical column and rotatable by a drive device between stand-by and access positions. Each carrier plate has a number of fields in which data carriers can be inserted and at least one opening on a concentric circle line. The openings form a cylindrical shaft extending over the entire height of the storage device when all plates are in the stand-by position. The carrier plates are accessed by the gripping transfer device via the cylindrical shaft.
Patent JP-3767903-B2 (JP)
IPC: A61B17/32
Filed: 1996-02-15
Granted: 2006-04-19
Abstract: A surgical instrument includes a support member that extends distally from a base, carrying at a distal region a window defining an opening. A surgical tool at least partially disposed in the distal region is movable with respect to the window to cut tissue extending through the opening. A shield also at least partially disposed in the distal region is movable with respect to the window to at least partially cover the opening.
Patent JP-3664408-B2 (JP)
IPC: F16C9/04
Filed: 1995-03-23
Granted: 2005-06-29
Abstract: PCT No. PCT/DE95/00414 Sec. 371 Date Aug. 29, 1997 Sec. 102(e) Date Aug. 29, 1997 PCT Filed Mar. 23, 1995 PCT Pub. No. WO95/27857 PCT Pub. Date Oct. 19, 1995In order to take account of dimensional variations in crankcases and connecting rods, the lower bearing shell (9) in the unmounted state is formed such that the outer contour is in the shape of an arc having a radius ra and the inner contour has the shape of a semi-ellipse having semi-axes ai and bi. The bearing semi-axis ai passes through the vertex (19) of the lower bearing shell (9). When the bearing is mounted, the contour of the upper bearing shell (8) remains unchanged while the lower bearing shell (9) is slightly deformed such that its outer contour assumes the shape of a semi-ellipse having semi-axes aa and ba. The short semi-axis ba passes through the vertex (19) of the lower bearing shell (9).
Patent JP-3627062-B2 (JP)
IPC: A23L27/20
Filed: 1995-05-05
Granted: 2005-03-09
Abstract: PCT No. PCT/FR95/00588 Sec. 371 Date Nov. 7, 1996 Sec. 102(e) Date Nov. 7, 1996 PCT Filed May 5, 1995 PCT Pub. No. WO95/30688 PCT Pub. Date Nov. 16, 1995Novel sweetening compound characterized in that it is N-[N-(3,3-dimethylbutyl)-L- alpha -aspartyl]-L-hexahydrophenylalanine 1-methyl ester of formula:   <IMAGE>   and its method of preparation characterized in that an aqueous/alcohol solution of pH 4.5-5 of aspartame and 3,3-dimethylbutyraldehyde at room temperature is treated with hydrogen at a pressure of 3 bars in the presence of a catalyst based on platinum such as platinum black and platinum oxide and in that the product formed is purified by precipitation and filtration after evaporation in vacuo of the alcohol part of the solvent.
Patent JP-3342874-B2 (JP)
IPC: A61K31/4184
Filed: 1996-04-17
Granted: 2002-11-11
Abstract: The present patent application discloses compounds having the formula   <CHEM> or a pharmaceutically acceptable salt thereof or an oxide thereof wherein     R<3> is <CHEM>  wherein A, B and D each is CH, or one or two of A, B and D is N and the others are CH; R<11> is phenyl, benzimidazolyl, or monocyclic heteroaryl all of which may be substituted one or more times with substituents selected from alkyl, alkoxy, phenyl, halogen, CF3, amino, nitro, cyano, acyl, acylamino, phenyl and monocyclic heteroaryl; and one of R<6> and R<7> is hydrogen and the other is furanyl or isoxazolyl each of which may be substituted one or more times with substituents selected from halogen, alkyl, alkoxy and phenyl.   The compounds are useful for the treatment of various central nervous system disorders such as epilepsy and other convulsive disorders, anxiety, sleep disorders and memory disorders. <IMAGE>
Patent JP-3364658-B2 (JP)
IPC: A61P25/08
Filed: 1996-09-16
Granted: 2003-01-08
Abstract: Lyophilized pharmaceutical compositions containing botulinum toxin or botulinum neurotoxin and effective amounts of trehalose and methionine have a shelf life of up to 4 months or more at room temperature and above.\!
Patent JP-3442402-B2 (JP)
IPC: A61F2/06
Filed: 1997-05-20
Granted: 2003-09-02
Abstract: Continuously flat-woven implantable tubular prostheses have seamless woven sections which gradually change the number of warp yarns to smoothly transition, i.e., taper, from one diameter to another. Multi-diameter endoluminal grafts having a variety of shapes and configurations are made using a seamless weaving process without unacceptable voids or gaps in the tubular wall.
Patent ES-2262443-B2 (ES)
Title: Procedimiento de fabricacion de pisos de calzado y producto obtenido.
Inventor: URBAN BRU FRCO MANUEL
IPC: A43B13/12
Filed: 2006-02-07
Granted: 2008-03-01
Abstract: Procedimiento de fabricación de pisos de calzado y producto obtenido. Consiste en un piso de calzado que incorpora una membrana impermeable al agua, pero permeable al aire, complementada con unas aberturas del piso para obtener una buena ventilación de los pies a fin de evitar el sudor de los mismos. El procedimiento se caracteriza porque la membrana se integra en el piso durante el proceso de inyección del material del piso, sin tener que añadir adhesivo o cualesquiera otros elementos. A través de las aberturas del piso son visibles porciones de membrana que pueden mostrar distintos dibujos y decoraciones, pudiendo tener las aberturas cualquier distribución, formas y tamaños, según se desee.
Patent ES-2381950-B2 (ES)
Title: Liposomas con anticuerpos contra marcadores de la zona peri-infarto cerebral.
Inventor: CASTILLO SANCHEZ JOSE
IPC: A61K39/395
Filed: 2010-11-08
Granted: 2013-03-13
Abstract: Liposomas con anticuerpos contra marcadores de la zona peri-infarto cerebral. La invención se refiere a liposomas, marcados con una sustancia fluorófora como la rodamina o con un agente de resonancia magnética como el gadolinio, que incorporan en su superficie un anticuerpo dirigido contra la proteína de choque térmico HSP70, unido al liposoma por un resto maleimida, y que incorporan también en su composición PEG para aumentar su estabilidad y evitar respuestas inmunes. Dichos liposomas que acumulan en las células que sobreexpresan la proteína HSP70, por lo que pueden utilizarse para identificar dichas células, incluidas las que forman parte de la región peri-infarto cerebral, en la que se sobreexpresa dicha proteína. Los liposomas con gadolinio pueden también utilizarse en un procedimiento para obtener imágenes del cerebro por resonancia magnética a partir de las cuales se puede determinar la región peri-infarto, que será aquella en la que se acumulará más gadolinio (mayor contraste).