Patent DE-102010006439-A1 (DE)
Title: Equipment or system, in which blood is derived from body's blood circulation and through a filter with computer-drawn, nanometer precise structures, useful for automated killing or harming of HIV, bacteria and fungi
Inventor: MOESCH DOMINIK
IPC: A61M1/34
Filed: 2010-02-01
Abstract: Equipment or system, in which the blood is derived from the body's blood circulation and through a filter with computer-drawn, nanometer precise structures, by virtue of its porosity, of 200 nm (120-500 nm), is claimed, where only the blood plasma and HIV (diameter of 100-120 nm) contained in blood plasma can pass therethrough, so that the filter is additionally passable for the blood platelets with a diameter of 1500-3000 nm, contained in the blood plasma. Equipment or system, in which the blood is derived from the body's blood circulation and through a filter with computer-drawn, nanometer precise structures, by virtue of its porosity, of 200 nm (120-500 nm), is claimed, where only the blood plasma and HIV (diameter of 100-120 nm) contained in blood plasma can pass therethrough and the filter has a pore size of 3000-4500 nm, so that the filter is additionally passable for the blood platelets with a diameter of 1500-3000 nm contained in the blood plasma. Then, the HIV viruses contained in the blood plasma are irradiated by a radiation-generating element in order to make the HIV virus harmless or reproductively sterile, e.g. an electromagnetic radiation of appropriate wavelengths can be used (e.g. UV-C radiation, thermal radiation) or an ionizing radiation such as beta -radiation, gamma -radiation, X-rays, neutron beams, proton beams, ion beams, possibly even alpha -radiation. Alternatively, the HIV virus can be made reproductively sterile based on a vibration-generating element, where the HIV viruses are damaged using ultrasonic vibrations, or based on a destructive element, or using shearing forces, and such techniques used by the viruses in the vaccine preparation are comminuted, and these are given in fragmentary form, or the radiation-generating element can also be replaced by a filter with a small pore size, then the HIV virus cannot pass, so that they accumulate in the flow direction before this filter and can be aspirated. Thus, it can be achieved based on the newly developed filter with computer-drawn, nanometer precise structures, e.g. to release the blood of 90-99% of old reproductively sterile HIV virus before it is returned to the body's blood circulation. This is possible in part because the liquid flow rate of the filter often can be higher than the hemodialysis, for the following reasons: (a) the device does not rely on the slow and ineffective process of concentration equalization by reverse osmosis and not to a correspondingly low working pressure and efficiency; (b) in contrast to the dialysis, blood plasma is not lost, which only be regenerated again by the body, further no amino acids, antibodies, nutrients and minerals; (c) not only the pressure in the filter can often be higher than in hemodialysis, because for the filter also a much larger pore size is used than for a dialysis filter, e.g. the cross-sectional area of a single filter pore of the filter is 2500-9000000 times larger than the cross-sectional area of a filter pore of a dialysis filter, thus at the same time, the handling of the used filters is uncomplicated; (d) due to a continuous self-cleaning function during the filtering process, the filter performance can be further increased. After the irradiation by the radiation-generating element, the harmless HIV left in the blood and the blood is returned into the body's circulatory system, through the abandonment of innocuous HIV in the blood, while also giving one inoculation achieved. This vaccine is administered using the body's own HIV virus or HIV mutation variants, where antibodies are automatically produced in the course of immune response, which is resistant to HIV mutation, because the HIV mutation variants are itself the vaccine. As in dialysis, 10-hour treatment is possible, but also a continuous treatment, which lasts for several weeks or months, which in contrast to dialysis no blood plasma is lost, where no further amino acids, antibodies, nutrients and minerals are regenerated by the body; the purpose of treatment consists of e.g. restoration of the HIV to the initial stage, and appropriate treatment is carried out, e.g. every 7-10 years, or only when AIDS actually erupts, and then after the treatment, a number of HIV antibodies is provided by the immune system (as opposed to a primary infection, which also begins with the initial stages of HIV). To avoid coagulation of the blood in the filter, an anticoagulant agent such as heparin (multiple sugar) or a coumarin (vitamin K antagonist) is administered during the dialysis, and it is possible to reduce the dose of the corresponding means. In order to ensure the flow of blood within the device, e.g. the same techniques can be used as in the dialysis, and for the transport of blood, blood pumps are used, As in the dialysis, the device is practically integrated to the blood circuit (to treat blood products), within the device, the blood can flow in a circuit or the device can be traversed without a circulation of the blood, where the device has internal sensors and a screen. ACTIVITY : Anti-HIV; Antibacterial; Fungicide. MECHANISM OF ACTION : None given.