baber/WOPTO huggingface dataset:
Patent AT-E483618-T1 (AT)
Inventor: GAY JORDAN
IPC: B62M7/12
Filed: 1998-12-10
Granted: 2010-10-15
Abstract: A vehicle drive assembly with a motor configured for driving the vehicle and including a rotatably driven motor shaft. A first swing arm has a first end housing the motor and a second end pivotably and supportively attachable to a vehicle body, with an elongated portion joining the ends. The vehicle also has a gearbox housing configured for transmitting torque to a road surface through a road engaging member, and a transmission directly engaged with the motor shaft and housed within the gearbox housing. The transmission is configured for transmitting torque from the motor shaft to the housing. A second swing arm is pivotably and supportively attachable to the vehicle body. An axle is fixed to the second swing arm, received within the gearbox housing, and attached to the transmission such that the second swing arm is supported by the transmission. The transmission preferably includes a planetary gear reduction unit with a gear carrier rotationally fixed to the first swing arm and a plurality of gears operatively associated with the shaft and the gearbox housing to transmit torque therebetween. Preferably at least one of the gears is mounted to the gear carrier, more preferably a plurality of planetary gears is mounted to the gear carrier.
Patent AT-E226290-T1 (AT)
Inventor: SANDER EDMUND
IPC: B60K20/00
Filed: 1999-08-23
Granted: 2002-11-15
Abstract: The first end of a spiral spring (8) is fixed in place on a rotating inhibitor (6). The spiral spring is attached to a support (11) at a distance from its second free end (13). A step (14), matching the first end of the spiral spring, is provided on the casing (2) of the selector device near the axis of rotation of the inhibitor. A selector lever operating element (4) between a fixed bearing (9) and the support engages the spiral spring for unlocking.
Patent AT-E215657-T1 (AT)
Inventor: SCHMIDT MICHAEL E
IPC: E05G1/024
Filed: 1999-12-10
Granted: 2002-04-15
Abstract: The armour plate (20) has a stainless steel plate (21), e.g. V2A, which has a ceramic layer (25) on at least one side. Preferably, the ceramic layer is made up of individual plates, which are glued to the stainless steel plate. The armour plate may have openings (22). An Independent claim is included for a safe or strong box.
Patent AT-E292952-T1 (AT)
Inventor: AUDOUSSET MARIE-PASCALE
IPC: A61K8/00
Filed: 1999-10-25
Granted: 2005-04-15
Abstract: Composition for oxidation dyeing of keratinic fibers comprises: (a) developer(s) selected from p-aminophenol derivatives (I) and their acid-addition salts, but no additional developer selected from pyrimidine, pyrimidine derivatives, 2-(2-hydroxyethyl)-p-phenylenediamine and their acid-addition salts; and (b) a coupler selected from 1,3-bis(2-hydroxyethylamino)-2-methylbenzene and its acid-addition salts. Composition for oxidation dyeing of keratinic fibers comprises: (a) developer(s) selected from p-aminophenol derivatives (I) and their acid-addition salts, but no additional developer selected from pyrimidine, pyrimidine derivatives, 2-(2-hydroxyethyl)-p-phenylenediamine and their acid-addition salts; and (b) a coupler selected from 1,3-bis(2-hydroxyethylamino)-2-methylbenzene and its acid-addition salts. R1 = H, F, 1-4C alkyl, 1-4C monohydroxyalkyl, 2-4C polyhydroxyalkyl, (1-4C)alkoxy(1-4C)alkyl or monohydroxy(1-4C)alkylamino(1-4C)alkyl; and R2 = H, F, 1-4C alkyl, 1-4C monohydroxyalkyl, 2-4C polyhydroxyalkyl, 1-4C aminoalkyl, cyano(1-4C)alkyl or (1-4C)alkoxy(1-4C)alkyl, provided that one (and only one) of R1 and R2 is H. Independent claims are also included for: (1) a method for dyeing keratinic fibers comprising applying the oxidation dye composition and developing the color with an oxidizing agent added just before use or applied simultaneously or sequentially in an oxidizing composition; and (2) a kit comprising a compartment containing the oxidation dye composition and a compartment containing an oxidizing composition.
Patent AT-E253621-T1 (AT)
Inventor: BOLLE THOMAS
IPC: B27K3/52
Filed: 1999-03-10
Granted: 2003-11-15
Abstract: The invention relates to a method of protecting wood against light-induced degradation by treatment with a stain or impregnation which penetrates the surface of the wood comprising     a) at least one organic solvent;   b) a hindered amine compound of formula I or II <CHEM>  where   G1 and G2 are independently alkyl of 1 to 4 carbon atoms or are together pentamethylene, Z1 and Z2 are each methyl, or Z1 and Z2 together form a linking moiety which may additionally be substituted by an ester, ether, hydroxy, oxo, cyanohydrin, amide, amino, carboxy or urethane group,   E is oxyl or hydroxyl,   X is an inorganic or organic anion, and   where the total charge of cations h is equal to the total charge of anions j.
Patent AT-E304865-T1 (AT)
Inventor: SCHWARZ ALEXANDER
IPC: A61K31/715
Filed: 1999-04-15
Granted: 2005-10-15
Abstract: One aspect of the present invention relates to methods and compositions for attenuating xenograft rejection by administering, to an animal receiving the xenograft, an amount of a polymer-derivatized xenoantigen (hereinafter "xenopolymer") effective for inhibiting or lessening the severity of hyperacute rejection response (HAR), or other immunological response to the graft, that is dependent on the presence of the xenoantigen on the grafted tissues or cells. In certain embodiments, the xenopolymer is administered in an amount sufficient to neutralize host antibodies ("xenoreactive antibodies" or "XNA") immunoreactive with the xenoantigen. The xenopolymer may additionally, or alternatively, be used as a tolerogen (or anergen) for the xenoantigen, e.g., able to suppress, to some degree, the production/secretion of XNAs by the immune system of the host.
Patent AT-E225316-T1 (AT)
Inventor: COOWAR FAZLIL
IPC: C01G45/00
Filed: 1999-08-31
Granted: 2002-10-15
Abstract: An oxide LiMnO2 which has a layered monoclinic structure, and in which a minor part of the manganese may be replaced by another transition metal, is made by a two-stage process. Firstly NaXo2 with a layered structure of the alpha-NaFeO2-type is made by reacting stoichiometric amounts of a sodium salt and a salt of the metal X in solution so as to form a precipitate, drying and heat treating the precipitate at a temperature between 650 and 720° C. in air, and then rapidly cooling the precipitate to room temperature in air. Then the NaXO2 is subjected to ion exchange with a lithium salt in solution in a non-alcoholic solvent at a temperature between about 140 and 210° C. The resulting lithium manganese oxide can be used as the cathode material in a rechargeable lithium cell.
Patent AT-E314147-T1 (AT)
Inventor: TANAKA HAYAO AKITA SUMITOMO BA
IPC: B01L3/00
Filed: 1999-10-28
Granted: 2006-01-15
Abstract: A container for an immunologic assay in which the saturation adsorption of molecules for use in the assay is 1 x 10<-1> pmol/cm<2> or lower. The container is free from non-specific adsorption causative of reagent loss, sensitivity decrease, and precision decrease.
Patent AT-E247754-T1 (AT)
Inventor: AALAND OVE
IPC: E04G3/00
Filed: 1999-12-17
Granted: 2003-09-15
Abstract: Description is given of an arrangement of a working platform (16) which is suspended in a superjacent support construction, such as a ceiling construction, tier of beams or the like, with the working platform (16) being connected to the support construction by being mounted to a yoke construction (26), and that the platform (16) is arranged so that it can be raised or lowered in relation to the yoke construction. The arrangement is characterized in that the yoke construction comprises one or more extendable rods (40, 42, 44, 46), and with a given force can be brought to abut a superjacent support construction (12, 14) to in this way stabilise the relative position of the yoke construction/platform.
Patent AT-E290071-T1 (AT)
Inventor: KARLSSON ANNA
IPC: C12N15/09
Filed: 1999-12-10
Granted: 2005-03-15
Abstract: By inserting a DNA or RNA sequence comprising a subsequence showing a homology of at least 60%, preferably at least 80%, and most preferably at least 90% of the DNA sequence of SEQ. ID. NO. 1 into a cell, that cell will obtain a broad specificity for changing nucleoside analog prodrugs to active drugs by phosphorylation. Likewise this changement will occur at a high catalytic rate. Preferably the DNA sequence is inserted into the cell by transformation with a suitable virus or another suitable vector. Such viruses and vectors also constitute a part of the present invention.
Patent AT-E275582-T1 (AT)
Inventor: REGBERG TOR
IPC: G01N30/00
Filed: 1999-12-20
Granted: 2004-09-15
Abstract: A method for selectively enriching/removing a serum albumin from a mixture of other compounds by contacting said mixture with M-B-X where M is matrix, B the spacer and X the affinity ligand, with the provision that M may contain further groups X linked via a spacer. The characterizing feature is that the ligand X has been selected among serum albumin-binding structures complying with the formula (I) in which the free valence binds to the spacer B; R1-10 are selected from hydrogen, electron-withdrawing groups, such as halogens and lower alkyl groups (C1-10) that possibly are substituted with electron withdrawing groups, such as halogens; Z and Y are selected among oxygen, sulphur or nitrogen, with the provision that the nitrogen may carry a positive charge. A method for screening for ligands structures that, when attached to an affinity matrix, selectively bind serum albumin. The method has the characterizing feature that water-soluble compounds that exhibit a benzene ring fused to a 5-membered heterocycle containing two or three heteroatoms, preferably two, selected from nitrogen, oxygen and sulphur after having been attached to a matrix, preferably in the 2-position, are screened for selective binding to albumin.
Patent AT-E265673-T1 (AT)
Inventor: MCCARTY WILLIAM A
IPC: G01D9/00
Filed: 1999-10-22
Granted: 2004-05-15
Abstract: A vibration coupling stud for use in a vibration monitoring system includes digital memory and temperature sensing devices. Data is transferred between the vibration coupling stud and a vibration monitor. Data stored in the stud may include measuring point identification, prior measurement data, machine or bearing part numbers, and alarm limits.
Patent DE-19781677-T1 (DE)
Inventor: ZIGERLIG MAX
IPC: C08J9/08
Filed: 1997-06-17
Abstract: A flexible cleaning element for rotating brushes for automatic washing of vehicles, suitable for being attached to a rotating support and made of an expanded closed-cell synthetic resin is provided. The expanded synthetic resin includes a copolymer that is obtained by adding vinyl acetate to it.
Patent DE-674004-T1 (DE)
Inventor: MANDRAND BERNARD
IPC: C12N5/08
Filed: 1995-02-06
Abstract: Composition comprising two pathogenic and/or infective agents associated with multiple sclerosis, namely a first agent which consists of a human virus possessing reverse transcriptase activity and related to a family of endogenous retroviral elements, or a variant of said virus, and a second agent, or a variant of said second agent, these two pathogenic and/or infective agents originating from the same viral strain chosen from the strains designated, respectively, POL-2 deposited with the ECACC on Jul. 22 1992 under Accession Number V92072202 and MS7PG deposited with the ECACC on Jan. 8 1993 under Accession Number V93010816, and from their variant strains.
Patent CY-1107732-T1 (CY)
Inventor: PELISSON ISABELLE
IPC: A61K8/34
Filed: 2007-09-12
Abstract: Topically applicable skin depigmenting compositions, suited for treatment of such hyperpigmentary disorders as melasma and chloasma, contain a thus effective amount of at least one skin depigmenting active agent, for example hydroquinone or 4-hydroxyanisole, in admixture with a depigmentation-accelerating amount of adapalene (6-[3-(1-adamantyl)-4-methoxyphenyl]-2-napthanoic acid), and optionally with at least one sunscreen, formulated into a topically applicable, physiologically acceptable medium therefor.
Patent CY-1106919-T1 (CY)
Title: Μεθοδος για τη βελτιωση της σταθεροτητας μιας φαρμακευτικης συνθεσης
Inventor: FETZ ANDREA
IPC: A61K31/4535
Filed: 2007-10-08
Abstract: Η παρούσα εφεύρεση περιγράφει ειδικότερα μία μέθοδο για την σταθεροποίηση μίας φαρμακευτικής σύνθεσης η οποία συνίσταται στο να έρχεται σε επαφή η εν λόγω σύνθεση με ένα πολυμερές υλικό, μέθοδος η οποία περιλαμβάνει ειδικότερα το βήμα της αποστείρωσης με οξείδιο του αιθυλενίου.
Patent CY-1106976-T1 (CY)
Title: Εκλεκτικοι αγωνιστες ep4 υποδοχεα στη θεραπεια οστεοπορωσης
Inventor: CAMERON K O'KEEFE
IPC: A61P19/08
Filed: 2007-11-06
Abstract: Η εφεύρεση αυτή κατευθύνεται σε εκλεκτικούς αγωνιστές ΕΡ4 υποδοχέα προσταγλανδίνης του τύπου (Ι), όπου τα R2, Χ, Ζ και Q είναι όπως ορίζονται στη περιγραφή. Η εφεύρεση αυτή επίσης κατευθύνεται σε φαρμακευτικές συνθέσεις που περιέχουν αυτές τις ενώσεις. Αυτή η εφεύρεση κατευθύνεται επίσης σε μεθόδους θεραπείας καταστάσεων που εμφανίζονται με χαμηλή οστική μάζα, ιδιαιτέρως οστεοπόρωση, ευθραυστότητα, οστεοπορωτικό κάταγμα, μειονέκτημα οστού, ιδιοπαθητική απώλεια οστού της παιδικής ηλικίας, φατνιακή απώλεια οστού, γναθική απώλεια οστού, κάταγμα οστού, οστεοτομία, απώλεια οστού που συνδυάζεται με περιοδοντίτιδα ή προσθετική ενδοανάπτυξη σε ένα θηλαστικό που περιλαμβάνει χορήγηση αυτών των ενώσεων.
Patent CY-1113787-T1 (CY)
Title: Νεα διαδικασια για τη διαστερεοεπιλεκτικη ληψη μιας πρωτογενους χειρομορφης αμινης σε ενα στεροειδες
Inventor: BERNARD DANIEL
IPC: C07J41/00
Filed: 2011-11-02
Abstract: Η παρούσα εφεύρεση έχει ως αντικείμενο μια διαστερεοεπιλεκτική διαδικασία για τη λήψη μιας πρωτογενούς αμίνης σε ένα στεροειδές, που συνίσταται στη μείωση ενός όξιμου με το λίθιο σε αμμωνία σε χαμηλή θερμοκρασία μέσα σε ένα μείγμα αιθέρα - αλκοόλης.
Patent CY-1112431-T1 (CY)
Inventor: BOUSTANI ROLAND
IPC: A61F5/00
Filed: 2011-11-04
Abstract: The gastric ring comprises an elongate element that can be deformed into a loop between a distal end portion and a proximal end portion, together with closure means suitable for folding the elongate element into a loop and for fastening the distal and proximal end portions together once they have been moved close to each other while looping the ring. At least the elongate element is made of a material that is resorbable, preferably over a period of about or less than 2 years, e.g. of a poly-alpha-hydroxy acid. The elongate element is constituted by a proximal link, a distal link, and intermediate links hinged about pivot axes.
Patent CY-1115817-T1 (CY)
Title: Υποκατεστημενα αμινοπροπιονικα παραγωγα ως αναστολεις νεπριλυσινης
Inventor: COPPOLA GARY MARK
IPC: C07C233/47
Filed: 2014-11-13
Abstract: Η παρούσα εφεύρεση παρέχει μια ένωση του χημικού τύπου I’ ή ένα φαρμακευτικά αποδεκτό άλας αυτής, όπου τα R1, R2, R3, Β1, Χ και n ορίζονται στο παρόν κείμενο. Η εφεύρεση σχετίζεται επίσης με μια μέθοδο για την παρασκευή των ενώσεων της εφεύρεσης και τις θεραπευτικές τους χρήσεις. Η παρούσα εφεύρεση παρέχει περαιτέρω έναν συνδυασμό για φαρμακευτικά δραστικούς παράγοντες και φαρμακευτικές συνθέσεις.
Patent CY-1115838-T1 (CY)
Title: Μεθοδος για τη σταθεροποιηση φαρμακοτεχνικων μορφων που περιεχουν μικροοργανισμους
Inventor: RUDOLPH MARKUS
IPC: B65D81/26
Filed: 2014-12-18
Abstract: Η εφεύρεση αφορά σε μια μέθοδο για τη σταθεροποίηση στερεών φαρμακοτεχνικών μορφών, τα οποία περιέχουν τουλάχιστον ένα γένος μικροοργανισμών, καθώς και μια μονάδα συσκευασίας που περιλαμβάνει μια συσκευασία καθώς και μια στερεά φαρμακοτεχνική μορφή, η οποία περιέχει τουλάχιστον ένα γένος μικροοργανισμών.
Patent CY-1117386-T1 (CY)
Title: Διπλο καλυμμα για μπαταριες αποθηκευσης
Inventor: MARASCHI MARCO
IPC: H01M50/367
Filed: 2016-02-04
Abstract: Ένα κάλυμμα για μπαταρία αποθήκευσης, το οποίο απαρτίζεται από ένα κύριο στοιχείο κλεισίματος (1) με οπές φόρτωσης (33), ένα δευτερεύον στοιχείο κλεισίματος (4) στερεωμένο επάνω στο κύριο στοιχείο, και έναν αγωγό (52), διευθετημένο για την εκφόρτωση των αερίων που δημιουργούνται στο εσωτερικό του περιβλήματος της μπαταρίας. Το κύριο στοιχείο και το δευτερεύον στοιχείο μαζί σχηματίζουν μια δομή που μοιάζει με κουτί (3, 4), η οποία οριοθετεί έναν θάλαμο (6) σε επικοινωνία ροής με τις οπές, και στο εσωτερικό της οποίας οριοθετείται ένας λαβύρινθος, ο οποίος συνδέει τις οπές του κυρίου στοιχείου στον αγωγό εκφόρτωσης αερίων. Ο θάλαμος (6) υποδιαιρείται σε μια πληθώρα υποθαλάμου (6a, 6b, 6c), οι οποίοι βρίσκονται μεμονωμένα σε επικοινωνία ροής με έναν δίαυλο συλλογής (41) που επικοινωνεί με τον αγωγό εκφόρτωσης αερίων (52). Ο δίαυλος συλλογής (41) αποτελείται από ένα πρώτο και ένα δεύτερο διαμήκες τμήμα διαύλου (41a, 41b), τα οποία εκτείνονται κατά μήκος των απέναντι πλευρών του θαλάμου, και ένα εγκάρσιο τμήμα διαύλου (41c), το οποίο εκτείνεται κατά μήκος της κεντρικής γραμμής του θαλάμου και ενδοσυνδέει το πρώτο και το δεύτερο διαμήκες τμήμα διαύλου.
Patent CY-1125263-T1 (CY)
Title: Συνθεσεις και μεθοδοι για την αναστολη γονιδιακης εκφρασης της lpa
Inventor: Melquist Stacey
IPC: C12N15/113
Filed: 2021-11-08
Abstract: Περιγράφονται παράγοντες παρεμβολής RNA (RNAi) και συζεύγματα παράγοντα RNAi για αναστολή της έκφρασης του γονιδίου (apo(a)) LPA. Περιγράφονται επίσης φαρμακευτικές συνθέσεις που αποτελούνται από έναν ή περισσότερους παράγοντες RNAi LPA προαιρετικά με μια ή περισσότερες πρόσθετες θεραπευτικές. Η αποδέσμευση των περιγραφέντων παραγόντων RNAi LPA σε ηπατικά κύτταρα in vivo παρέχει αναστολή της γονιδιακής έκφρασης LPA και θεραπευτική αγωγή καρδιαγγειακών και σχετιζόμενων με καρδιαγγειακά ασθενειών.
Patent GR-890300116-T1 (GR)
Title: Method and device for compensating at the receiving side the phase noise of a transmitting laser and of a local laser in a coherent optical communication system with heterodyne detection
Inventor: BEKOOIJ JOHAN PIETER
IPC: H04B10/00
Filed: 1990-01-31
Abstract: The invention relates to a method for compensating, in a coherent optical communication system with heterodyne detection, at the receiving side phase noise of the transmitting and of the local laser. Characteristic of the present method is that the phase-noise compensation takes place in the LF domain. The two MF heterodyne signals (Imf and Pmf) are first demodulated into LF signals (in which there is still noise), which are subsequently substracted from one another, due to which the respective noise components cancel out each other. Preferably a local laser signal which is, qua frequency, between the two other HF signals is chosen. This offers the advantage that the two MF heterodyne signals can be modulated by one and the same demodulator; because for the compensation of phase noise the demodulated MF signals (Ilf respectively Plf) which are, qua phase noise, in opposite phase with regard to each other are then added to one another. The advantage of the method according to the invention is that the bandwidth for which the receiver has to be suitable is relatively small.
Patent GR-990300041-T1 (GR)
Title: New reagents and methods for erythrocyte lysis
Inventor: VAN AGTHOVEN ANDRE
IPC: C12N1/06
Filed: 1999-05-04
Abstract: A lysing reagent (I) for the cytometric analysis of leukocytes is new, and comprises a nitrogen containing heterocycle used at pH 4-9. An Independent claim is also included for a method for lysing erythrocytes comprising the action of (I) and a blood sample treated with an anticoagulant agent. The nitrogen containing heterocycle is used in concentrations of 0.01-0.2 M. The reagent further comprises chlorine as an anion to maintain the desired pH and a cation (especially carbonate, hydrogencarbonate or borate). The reagent further comprises a buffer, an anticoagulant agent and/or an aliphatic aldehyde.
Patent HR-P20100024-T1 (HR)
Inventor: LERESTIF JEAN-MICHEL
IPC: C07D223/16
Filed: 2010-01-13
Abstract: Postupak sinteze spojeva formule (I): pri čemu R1 i R2, koji mogu biti isti ili različiti, svaki predstavlja ravnu ili razgrananu skupinu (C1-C8)alkoksi ili tvore, zajedno s atomom ugljika koji ih nosi, 1,3-dioksanski 1,3-dioksolanski ili 1,3-dioksepanski prsten, naznačen time, da je spoj formule (VI): pri čemu su R1 i R2 ranije ovdje definirani, izložen reakciji katalitičke hidrogenacije, u ne-kiselom otapalu a potom se reakcijska smjesa filtrira kako bi se dobio spoj formule (I). Patent sadrži još 8 patentnih zahtjeva.
Patent HR-P20110957-T1 (HR)
Inventor: BALDWIN IAN ROBERT
IPC: C07D413/12
Filed: 2011-12-20
Abstract: Farmaceutski pripravak namijenjen za inhalacijsku primjenu, naznačen time što sadrži spoj formule (I) ili njegovu farmaceutski prihvatljivu sol: gdje: R1 jeC1-6alkil; C3-7cikloalkil ili C3-7cikloalkil(C1-4alkil)-, gdje je C3-7cikloalkil izborno supstituiran s jednim ili više supstituenata, koje se bira između =O i OH; C4-7cikloalkil, kondenziran s arilnim prstenom; Aril ili aril(C1-6alkil)-, gdje je aril izborno supstituiran s jednim ili više supstituenata, koje se bira između C1-6alkila, C1-6alkilCONR6-, C1-6alkilCO-, halogena, -CF3, -(CH2)mOH, -OCF3, C1-6alkoksi-, C1-6alkoksi(C1-4alkil)-, C1-6alkoksiC2-6alkoksi-, C1-6alkoksikarbonila, -CN, R4R5NCO, R7R8N-, R9R10NCONR11, HO(CH2)2-6O-, R12R13NSO2(CH2)m-, (4-morfolinil)C2-6alkoksi, -NR14SO2C1-6alkil, ariloksi, heteroarila (izborno supstituiranog s C1-6alkilom), CO2H, R21R22N(C1-4alkil)-, C1-6alkoksiCONR23(CH2)m-, arila (izborno supstituiranog s C1-6alkilom); Aril, kondenziran s C4-7cikloalkilnim prstenom, gdje je cikloalkilni prsten izborno supstituiran s jednim ili više =O; Aril, kondenziran s heterociklilnim prstenom, gdje je heterociklilni prsten izborno supstituiran s jednim ili više supstituenata, koje se bira između =O, -COC1-4alkila, C1-4alkila; Heteroaril ili heteroaril(C1-6alkil)-, gdje je heteroaril izborno supstituiran s jednim ili više supstituenata, koje se bira između: C1-6alkila, aril(C1-4alkil), C1-6alkoksi, halogena, C1-6alkoksiCO; iliHeterociklil, izborno kondenziran s arilnim ili heteroarilnim prstenom; R2 je vodik ili C1-6alkil; R34 je skupina formule: gdje R3 jeC1-6alkil, izborno supstituiran s jednim ili više supstituenata, koje se bira između -OH, -NR16COR15, -NR17R18, -CO2R24, C1-6alkoksiCONR25-, -CONR26R27, C1-6alkoksi-, C1-6alkilSO2NR33-, ili skupina s jednom od sljedećih formula: C3-7cikloalkil; Aril ili aril(C1-6alkil)-, gdje je aril izborno supstituiran s jednim ili više supstituenata, koje se bira između C1-6alkil-, halogen-, C1-6alkoksi-, -CO2R28, -CH2CO2H, -OH, arila (izborno supstituiranog s C1-6alkoksi skupinom), heteroarila, -CONR29R30, C3-7cikloalkoksi, C3-7cikloalkil(C1-6alkoksi)-, -CF3;Heteroaril ili heteroaril(C1-6alkil)-, gdje je heteroaril izborno supstituiran s jednomm ili više C1-6alkilnih ili -CONR29R30 skupina; iliHeterociklil, koji je izborno supstituiran s jednim ili više supstituenata, koje se bira između C1-6alkil-, C1-6alkilCO-, C3-7cikloalkilCO-, heteroarilCO- (izborno supstituiranog s jednom ili više C1-4alkilnih skupina), C1-6alkoksiCO-, arilCO-, R31R32NCO-, C1-6 salkilSO2-, arilSO2, -heteroarilSO2 (izborno supstituiranog s jednim ili više C1-4alkilnih ili C1-4alkilCONH- skupina); heterociklil je vezan na S(=O)n ostatak preko atoma ugljika; m je 0-6; n je 0, 1 ili 2; R19 je vodik ili C1-6alkil; R20 je vodik, C1-6alkil, halogen ili C1-6alkoksi; svaki od R4-18, R21-25, R28 i R31-33 neovisno predstavlja H, C1-6alkil; R26 i R27 neovisno predstavljaju H, C1-6alkil, C3-7cikloalkil ili heterociklil; R29 i R30 neovisno predstavljaju H, C1-6alkil, izborn