baber/WOPTO huggingface dataset:
Patent PT-1190132-E (PT)
Inventor: ROCHE BRUNO
IPC: D04H18/04
Filed: 2000-05-22
Abstract: A mechanism for the treatment of materials by pressurized water jets includes a body (1) for supplying water under pressure which includes a feeding chamber (2) extending over the whole length of the body, and wherein water under pressure is fed to the feeding chamber through a filter (4). The body also includes a distributing zone for distributing water under pressure over a whole treatment length against a plate (7) provided with micro-perforations which define water needles (8) directed against the surface (S) of the material to be treated. The material is supported by a carriage element subjected to a suction source eliminating the treatment water. Further, water transfer from the intake chamber (2) to the perforated plate (7), is done through a channel (22) with a rectangular cross-section extending over the whole length of the injector, from the periphery of the feeding chamber (2) up to the surface or the perforated plate (7), wherein the spacing between the side walls (21) of the channel and the height thereof produces a unidirectional and stable stream of water without turbulence.
Patent PT-1174535-E (PT)
Inventor: SCATIZZI MARIO
IPC: D06B23/10
Filed: 2001-06-08
Abstract: Apparatus for the automated preparation of solutions with combined metering system, of a type comprising a structure with a platform (1) upon which it is possible to position one or more containers for solid products, one or more bottle-like containers for liquid products, one or more containers for solutions, one or more empty and clean bottle-like containers, a carriage (2) movable onto said platform (1), characterized in that it comprises means (4), associated with said carriage (2), for the removal and handling of said bottles and for the removal, handling and actuation of at least said containers for solid products, and means (6) for preparing solutions and/or mixtures starting from the said solid substances. <IMAGE>
Patent PT-1280809-E (PT)
Inventor: MANZANARES IGNACIO
IPC: C07D317/00
Filed: 2001-04-12
Abstract: This invention relates to compounds of the formula: ##STR00001## wherein: the substituent groups defined by R.sub.1, R.sub.2 are each independently selected of H, C(.dbd.O)R', C.sub.1 C.sub.18 alkyl, C.sub.2 C.sub.18 alkenyl, C.sub.2 C.sub.18 alkynyl, or aryl; each of the R' groups is independently selected from the group consisting of H; OH; NO.sub.2; NH.sub.2; SH; CN; halogen; .dbd.O; C(.dbd.O)H; C(.dbd.O)CH.sub.3; CO.sub.2H; or C.sub.1 C.sub.18 alkyl, C.sub.2 C.sub.18 alkenyl, C.sub.2 C.sub.18 alkynyl, or aryl, each of which, independently, may be substituted with one or more substituents selected from the group consisting of halogen, cyano, hydroxy, nitro, azido; alkanoyl, carboxamido, alkyl, alkenyl, alkynyl, aryloxy, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, aminoalkyl, carbocylic aryl having 6 or more carbons, and aralkyl; X.sub.2 is OX.sub.1 or N(X.sub.1).sub.2 wherein each X.sub.1 is independently H, C(.dbd.O)R' where R' is as defined, C.sub.1 C.sub.18 alkyl, C.sub.2 C.sub.18 alkenyl, C.sub.2 C.sub.18 alkynyl, aryl, alkoxy, heterocyclyl, or two X.sub.1 groups together form a cyclic substituent on the nitrogen atom, or X.sub.1 is SO.sub.2CH.sub.3 when X.sub.2 is OX.sub.1, or N(X.sub.1).sub.2 is NHCOalkylCOOH, NHBiotin, NH(aa).sub.y where aa is amino acid acyl and Y is 1, 2 or 3 optionally with a amide terminal group, protected NHCOCH(NH.sub.2)CH.sub.2SH, NHCOalkenylaryl substituted with CF.sub.3, or m-methoxycarbonylbenzoylNH; wherein N(X.sub.1).sub.2 is not NH.sub.2; X.sub.3 is selected of OR.sub.1 where R.sub.1 is as defined, CN, (.dbd.O), or H; X.sub.4 is--H or C.sub.1 C.sub.18 alkyl; and X.sub.5 is selected of H, or R.sub.1 where R.sub.1 is as defined; provided that the compound is not ecteinascidin 583 or 597, which are useful for treating tumors.
Patent PT-1294714-E (PT)
Title: Thrombin receptor antagonists
Inventor: CHACKALAMANNIL SAMUEL
IPC: A61K31/444
Filed: 2001-06-13
Abstract: Heterocyclic-substituted compounds of formula (I) or a pharmaceutically acceptable salt thereof, are disclosed, wherein: Z is - (CH2)n-; (a); (b), wherein R 10  is absent; or, (c) wherein R 3  is absent; the single dotted line represents an optional double bond; the double dotted line represents an optional single bond; n is 0-2; Het is an optionally substituted mono-, bi- or tri-cyclic heteroaromatic group; B is -(CH 2 ) n3 -. wherein n 3  is 0-5, -CH 2 -O-, -CH 2 S-, -CH 2 -NR 6 -, -C(O)NR 6 -. -NR 6 C(O)-, (d), optionally substituted alkenyl or optionally substituted alkynyl; X is -O- or -NR 6 - when the double dotted line represents a single bond, or X is H, -OH or -NHR 20  when the bond is absent; Y is =O, =S, (H, H), (H, OH) or (H, C 1 -C 6  alkoxy) when the double dotted line represents a single bond or when the bond is absent, Y is =O, =NOR 17  (H, H). (H, OH), (H, SH), (H, C 1 -C 6  alkoxy) or (H, substituted-amino); R 22  and R 23  are independently -OH, -OC(O)R 30 , OC(O)NR 30 R 31 , or optionally substituted alkyl, alkenyl, alkynyl, heterocycloalkyl, aryl, cycloalkyl, cycloalkenyl, carbonyl, amino, alkoxy, alkenyloxy, alkynyloxy, heterocycloalkyloxy, cycloalkyloxy, or cycloalkenyloxy; or R 22  and R 10 , or R 23  and R 11 , can form a carbocyclic or heterocyclic ring; and the remaining variables are as described in the specification, Also disclosed are pharmaceutical compositions containing said compounds and their use as thrombin receptor antagonists and blinders to cannabinoid receptors.
Patent PT-1324652-E (PT)
Title: Transgenic drosophila melanogaster expressing beta amyloid
Inventor: COHEN DALIA
IPC: C12Q1/68
Filed: 2001-10-01
Abstract: Transgenic flies displaying altered phenotypes due to expression of the Abeta and C 99 portions of the human APP gene are disclosed. Use of these flies in a method to identify Drosophila genes and the human homologs of these Drosophila genes, that are potentially involved in Alzheimer's Disease, is also disclosed. The use of said human homologs as drug targets for the development of therapeutics to treat Alzheimer's Disease and other conditions associated with defects in the APP pathway, as well as pharmaceutical compositions comprising substances directed to these genes, are also disclosed.
Patent PT-1414396-E (PT)
Title: Personal care compositions
Inventor: EVISON JANE
IPC: A61K8/37
Filed: 2002-07-31
Abstract: There are described personal care compositions containing a) one or more dibenzoylmethane sunscreening agents; and b) a photostablising amount of a salicylate ester of formula (1): (2-OH)Ph-(CO)-O-R, wherein R represents an alkyl group consisting of a chain of from 7 to 16 carbon atoms substituted by at least one group selected from methyl and ethyl. The compound of formula (1) is preferably isodecyl salicylate or isotridecyl salicylate. The salicylate esters of formula (1) have a stabilizing effect on the compositions. The salicylate esters prevent or inhibit degradation of the sunscreening agents which would otherwise lead to a reduction in the efficacy of the sunscreening agents and an increase in the deleterious effects of exposure to sunlight on the user of the compositions or on the compositions themselves.
Patent PT-1472541-E (PT)
Title: Imaging agents and methods of imaging naaladase of psma
Inventor: KOZIKOWSKI ALAN P
IPC: G01N33/50
Filed: 2003-01-10
Abstract: The present invention relates to compounds particularly asymmetric urea compounds which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express NAALADase and/or PSMA. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express NAALADase and/or PSMA to which the compounds of the invention have an affinity.
Patent PT-1645929-E (PT)
Title: Communication card for mobile network devices and authentification method for users of mobile network devices
Inventor: LAUPER ERIC
IPC: G06F21/34
Filed: 2004-10-11
Abstract: A recoverable communications card (20) for a mobile network appliance (101;102) in which the communications card comprises a network interface for bidirectional transmission of data between the mobile network appliance and a network (30). The communications card comprises an identification module (23) for storing identification data of the users (40) and has a measuring device (21) for detecting biometric features (401,402) of a user (40). The communications card has an analysis module with a processor unit in which by using the analysis module at least one biometric feature of the user (40) can be compared with the stored identification data of the user. An independent claim is included for an authentification method for a user of a mobile network device.
Patent PT-1459945-E (PT)
Title: Vehicle with an airbag and an apparatus to ease the airbag`s deployment
Inventor: CHAUSSET FRANCOIS
IPC: B60R21/213
Filed: 2004-02-04
Abstract: The vehicle has a lining (20) interposed between a body (10) and an interior of the vehicle. An inflatable bag between the body and the lining is inflated by a bag inflation unit. A guidance strap extends between the body and the lining. The bag spreads itself inside the vehicle on inflation and pulls the straps. A mobile ramp draws the lining aside as the bag inflates in order to facilitate the clearance of the strap.
Patent PT-1716379-E (PT)
Title: Steam cracking furnace
Inventor: SPOTO MAURIZIO
IPC: F28F1/40
Filed: 2004-05-05
Abstract: An enhanced heat exchanger (10) consists of a tube (11) receiving heat from an external source. A fluid (F) to be heated flows through the free area created between the body (12, 12'), introduced inside the tube (11), and the tube itself. Both the tube (11) and the body (12, 12') heat the fluid (F). The body transfers to the fluid the energy received by the tube (11) by all the lo three modes of heat transfer: conduction, convection and radiation.
Patent PT-1663269-E (PT)
Title: Method for the production of a storage-resistant ivy leaf extract, and extract produced according to said method
Inventor: RUNKEL FRANK
IPC: B01J8/08
Filed: 2004-09-10
Abstract: Producing an ivy leaf extract containing hederacoside C and alpha -hederin comprising comminuting ivy leaves, steaming the comminuted leaves, extracting the steamed leaves with an extractant and optionally drying the extract, is new. Independent claims are also included for: (1) ivy leaf extract produced as above; (2) medicament comprising the extract. ACTIVITY : Antiinflammatory; Respiratory-Gen.; Antiasthmatic. No biological data given. MECHANISM OF ACTION : beta -Adrenergic receptor ligand.
Patent PT-1649667-E (PT)
Title: Self-managed mediated information flow
Inventor: JOHNSTON-WATT DUNCAN
IPC: H04L12/58
Filed: 2004-08-02
Abstract: The method also addresses failure detection and recovery.
Patent PT-1811864-E (PT)
Title: Liquid transition nutrition for infants
Inventor: SLIWINSKI EDWARD LUCIAN
IPC: A23L33/00
Filed: 2004-11-12
Abstract: Liquid composition suitable for supporting the transition period wherein the infant changes from a diet consisting of breast milk or liquid infant formula to solid foods with a viscosity 20-150 mPas, containing a digestible carbohydrate fraction and an indigestible carbohydrate fraction with at least 50 wt. % soluble indigestible oligosaccharide with a degree of polymerisation (DP) between 2 and 100.
Patent PT-1807434-E (PT)
Title: Thienopyridines as allosteric potentiators of the m4 muscarinic receptor
Inventor: ESTEBAN ALMUDENA RUBIO
IPC: A61K31/4365
Filed: 2005-10-18
Abstract: The present invention relates to selective allosteric potentiators of the Formula (I): or pharmaceutically acceptable salts thereof, for the treatment of disorders associated with M4 muscarinic receptors.
Patent PT-1777338-E (PT)
Title: A method for scrubbing flue gases
Inventor: HAEMAELAEINEN RISTO
IPC: D21C/
Filed: 2006-10-13
Abstract: In a method for processing flue gases, flue gases from an incineration
Patent PT-1932719-E (PT)
Title: Holding device for packing rods
Inventor: KLEY FRANK
IPC: B60P7/08
Filed: 2007-12-13
Abstract: Holding device comprises an operating element (4) formed as a rotary element (25) moving about a rotary axis and acting on adjusting units to bring the holding body (21) into a clamping position so that a first clamping element (27) presses against the holding rail when the rotary element rotates and/or a second clamping element presses against the holding rail in the axial direction of the rotary element. Preferred Features: The adjusting units have a rotary movement conversion device (31) which is connected to the rotary element. The rotary axis of the rotary element runs perpendicular to the front side of the holding rail.
Patent PT-1897643-E (PT)
Title: Milling cutter tool for high feed face milling
Inventor: FESTEAU GILLES
IPC: B23C5/20
Filed: 2004-10-05
Abstract: A cutting insert for milling operations, such as, face milling, slot milling, plunge milling, and ramping operations. The cutting insert exhibits a combination of favorable cutting edge strength, and unique cutting edge geometry, thus, allowing milling operations at relatively high feed rates. The cutting insert includes at least four cutting edges (12), wherein at least one of the cutting edges is a convex cutting edge. Certain embodiments of square cutting inserts will have four convex cutting edges which may be connected by nose corners (23). The convex cutting edge may comprise at least one of a circular arc, a portion of an ellipse, a portion of a parabola, a multi-segment spline curve, a straight line, or combinations of these. Wherein the convex cutting edge comprises a circular arc, the circular arc may have a radius greater than or equal to two times a radius of the largest circle that may be inscribed on the top surface.
Patent PT-2059525-E (PT)
Title: Split-core-particles for the presentation of foreign molecules, especially for vaccine applications, and method for their production
Inventor: NASSAL MICHAEL
IPC: C07K14/02
Filed: 2007-07-12
Abstract: Split core carrier for a foreign molecule against which an immune response is to be elicited comprises the N and C domains of a hepatitis B virus core protein as separate polypeptides, the foreign molecule being fused to the C-terminus of the N domain or the N-terminus of the C domain. The core protein is capable of binding capsid-like particles. An independent claim is also included for producing a carrier as above by expressing the foreign molecule and the N or C domain as a fusion protein or inserting a protease recognition sequence between the foreign molecule and the N or C domain and cleaving the product with the protease, and forming capsid-like particles. ACTIVITY : Antibacterial; Protozoacide; Virucide; Cytostatic. MECHANISM OF ACTION : Vaccine.
Patent PT-2091993-E (PT)
Title: Process for preparing modified polyisocyanate
Inventor: KAMIYAMA NOBUHIRO
IPC: C07C267/00
Filed: 2007-11-24
Abstract: Purpose: A process for preparing a liquid organic isocyanate having a carbodiimide group and/or an uretonimine group, excellent in storage stability. Solution: In a process for preparing a modified polyisocyanate by carbodiimidizing an organic polyisocyanate in the presence of a phospholine-based catalyst, silicon dioxide particles having a specific surface area of at least 400 m2/g and an oil absorption of at least 180 ml/100 g are used to adsorb and inactivate the catalyst to thereby terminate the carbodiimidization reaction.
Patent PT-2097400-E (PT)
Title: Fused substituted aminopyrrolidine derivative
Inventor: TAKEMURA MAKOTO
IPC: A61K31/47
Filed: 2007-12-28
Abstract: Intermediates of formula (Ia) or (Ib) are provided:   
wherein R 11  and R 21  represents a hydrogen atom or an amino-protecting group, and R 16  represents an amino-protecting group, useful for the production of quinolone synthetic antibacterial agent of formula (I) wherein substituents R 6  and R 7  taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure:
Patent PT-2222320-E (PT)
Title: Novel milk thistle extract, method for the production, and use
Inventor: NAGELL ASTRID
IPC: A61K36/28
Filed: 2008-12-23
Abstract: Procedure for producing a holy thistle flower extract with a silymarin-release rate of >= 80%, comprises obtaining an extract containing 15-85 wt.%, preferably 30-65 wt.% of silymarin with water-free alcohol, optionally filtering and concentrating the extract and subsequently drying and optionally comminuting. Independent claims are included for: (1) the holy thistle flower extract obtained by the above method, and exhibiting amorphous crystalline modification, where the crystalline portion amounts to less than 20%, preferably less than 7%; and (2) a pharmaceutical preparation comprising the extract. ACTIVITY : Hepatotropic; Antiinflammatory; Virucide; Anabolic; Antidote. MECHANISM OF ACTION : None given.
Patent PT-2158900-E (PT)
Title: Polymeric delivery formulations of leuprolide with improved efficacy
Inventor: DUNN RICHARD L
IPC: A61K/
Filed: 2001-09-21
Abstract: The present invention is directed to a flowable composition that is suitable for use as a controlled release implant. The flowable composition includes a biodegradable thermoplastic polyester that is at least substantially insoluble in aqueous medium or body fluid. The flowable composition also includes a biocompatible polar aprotic solvent. The biocompatible polar aprotic solvent is miscible to dispersible in aqueous medium or body fluid. The flowable composition also includes leuprolide acetate. The present invention is also directed to a method for forming the flowable composition. The present invention is also directed to a biodegradable implant formed in situ, in a patient. The biodegradable implant is formed by injecting a flowable composition within the body of the patient and allowing the biocompatible polar aprotic solvent to dissipate to produce a solid biodegradable implant. The present invention is also directed to a method of forming a biodegradable implant in situ, in a living patient. The method includes injecting a flowable composition within the body of a patient and allowing the biocompatible polar aprotic solvent to dissipate to produce a solid biodegradable implant. The present invention is also directed to a method of treating cancer in a patient. The method includes administering to the patient in need of such treatment an effective amount of a flowable composition of the present invention. The present invention is also directed to a method of reducing LHRH levels in a patient. The method includes administering to the patient in need of such LHRH reduction an effective amount of a flowable composition of the present invention. The present invention is also directed to a kit. The kit includes a first container and a second container. The first container includes a composition that includes a biodegradable thermoplastic polyester and a biocompatible polar aprotic solvent. The second container includes leuprolide acetate. The present invention is also directed to a solid implant. The solid implant includes a biocompatible thermoplastic polyester and leuprolide acetate. The solid implant has a solid or gelatinous microporous matrix, wherein the matrix is a core surrounded by a skin. The solid implant can further include a biocompatible organic solvent.
Patent PT-2259910-E (PT)
Title: Separating device
Inventor: HANSEN BERND
IPC: B26D5/08
Filed: 2009-02-07
Abstract: A separating device for cutting off individual containers (12) from a frame network made of a plastic material, particularly of polypropylene, has at least one punching device at least partially separating the containers (12) from a waste frame. Because the punching device can be moved by a ball screw drive (46) that can be driven by a drive unit, particularly in the form of an eclectic motor (48), along a punching axis (44) from a starting position to a punching position and back again, the separation can be done at high speed, determined by the screw shaft that can be driven by the electric motor.
Patent PT-2486041-E (PT)
Title: Hydroxyl, keto, and glucuronide derivatives of 3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile
Inventor: RODGERS JAMES D
IPC: A61P35/00
Filed: 2010-10-08
Abstract: The present invention provides hydroxyl, keto, and glucuronide derivatives of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile.
Patent PT-528678-E (PT)
Inventor: NISHITANI YASUHIRO
IPC: A61K31/41
Filed: 1992-08-18
Abstract: A pyrrolidylthiocarbapenem derivative represented by Formula I is provided: <CHEM> wherein R<1> is hydrogen or lower alkyl; R<2>, R<3> and R<4> are hydrogen, lower alkyl which can be substituted or an amino protecting group independently, or R<2> and R<3> together with a nitrogen atom to which R<2> and R<3> are bonded form a saturated or unsaturated cyclic group, or R<2>and R<4>, or R<3> and R<4> together with two nitrogen atoms and one sulfur atom in the sufamide group form a saturated or unsaturated cyclic group; each cyclic group can further include at least one atom selected from the group consisting of oxygen, sulfur and nitrogen, and each cyclic group can be substituted; X<1> is hydrogen or a hydroxy protecting group; X<2> is hydrogen, a carboxy protecting group, an ammonio group, an alkali metal or an alkaline-earth metal; and Y<2> is hydrogen or an amino protecting group.
Patent PT-598102-E (PT)
Inventor: HAUGEN DOUGLAS G
IPC: G02B26/02
Filed: 1993-05-27
Abstract: A method for electronically scanning a photodiode array that is sequentially illuminated by individual light beams by way of a shutter mechanism that has opening and closing transition times during which each light beam is only partially projected onto the array. An integrating light projected on the respective photodiodes of the photodiode array by each light beam over a predetermined period of time beginning after the opening transition time when the shutter mechanism is fully open and ending prior to initiation of the closing transition time while the shutter mechanism is still fully open and producing electrical signals corresponding to the light integrated by the respective photodiodes over the predetermined period of time and storing the electrical signals for subsequent use.
Patent PT-656178-E (PT)
Inventor: MARK DAVID A
IPC: A23L1/305
Filed: 1994-11-28
Abstract: Nutritional compsns. with an amino acid profile comprising less than 20% ammoniagenic acids, less than 0.2% arginine and at least 0.2% ornithine and/or citrulline, all based on total amino acids, are new. The compsns. may be used for enteral or parenteral (esp. peritoneal) feeding of patients with impaired ability to detoxify ammonia, e.g. those suffering from severe trauma, sepsis or renal or hepatic disease.
Patent PT-626385-E (PT)
Inventor: BULUSU A R C MURTY
IPC: A61K31/40
Filed: 1994-05-24
Abstract: The invention concerns the compounds of formula I <CHEM> wherein the substituents have various significances, in free form and, where such forms exist, in salt form. They can be prepared by various processes, e.g. by irradiation; oxidation; elimination; reduction; conversion by e.g. halogenation or acylation; deprotection of protected hydroxy groups; protection of free hydroxy groups; and separation of stereoisomeric mixtures into individual isomers. They are indicated for use as pharmaceuticals, especially as antiinflammatory, and as antiproliferative and antiinflammatory agents.