Patent SG-11201908706Q-A (SG)
Title: Method and apparatus for assessing diabetic circulatory complications
Inventor: CUCCIA DAVID
IPC: G01N21/25
Filed: 2018-03-22
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 27 September 2018 (27.09.2018) WIP0 I PCT o o Ho mEmo Imo VII IE (10) International Publication Number WO 2018/175787 Al (51) International Patent Classification: A61B 5/00 (2006.01) GO1N 21/25 (2006.01) (21) International Application Number: PCT/US2018/023856 (22) International Filing Date: 22 March 2018 (22.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/475,059 22 March 2017 (22.03.2017) US (71) Applicant: MODULATED IMAGING, INC. [US/US]; 17151 Gillette Avenue, Irvine, California 92614 (US). (72) Inventors: CUCCIA, David; 325 E. 19th Street, Costa Mesa, California 92627 (US). MAZHAR, Amaan; 306 1/2 Jasmine Avenue, Corona Del Mar, California 92625 (US). (74) Agent: ROBERTS, Kenneth, S.; One LLP, 4000 Macarthur Blvd., East Tower, Suite 500, Newport Beach, California 92660 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) = (54) Title: METHOD AND APPARATUS FOR ASSESSING DIABETIC CIRCULATORY COMPLICATIONS No Ole Diabete FIG. 30A N GC N N 00 O C (57) : Systems and methods directed to the assessment of circulatory complications due to advancement of diabetes. Embod- iments include an optical measurement device having a light source with one or more wavelengths and configured to illuminate an area of tissue, a detector configured to capture the light reflecting from one or more layers of the tissue at the one or more illumination wavelengths, a processor configured to compute, based on the detected signal of layer extracted circulatory data, one or more estimates of tissue vascular health, and a display or communication device (e.g., electronic data transfer) configured to store or report the tissue vascular health. In exemplary embodiments, the distribution of chromophores such as hemoglobin in different layers of skin is extracted using a combination of structured light in the visible and near-infrared regime.