baber/WOPTO huggingface dataset:
Patent EP-2911684-A2 (EP)
Inventor: FELBER BARBARA K
IPC: A61P37/04
Filed: 2013-10-23
Abstract: In one aspect, described herein are cyclical administration regimens for the administration of complexes comprising interleukin-15 ("IL-15") covalently or noncovalently bound to IL-15 receptor alpha ("IL-15Ra") to patients in order to enhance IL-15 -mediated immune function. In one aspect, these cyclical administration regimens achieve plasma levels of IL-15 above basal levels while minimizing the toxicity associated with IL-15 administration. In a specific aspect, the cyclical administration regimens are useful in the prevention, treatment, and/or management of disorders in which enhancing IL- 15-mediated function is beneficial, such as cancer, infectious diseases, immunodeficienices and lymphopenia. Also described herein are purified soluble forms of IL-15Ra, cells that recombinantly express soluble forms of IL-15Ra, and compositions comprising complexes of IL-15 covalently or non-covalently bound to soluble forms of IL-15Ra. Further described herein are host cells that recombinantly express IL15-Ra derivatives comprising a mutation or deletion in the extracellular domain cleavage site, including IL-15Ra derivatives comprising the extracellular domain of IL-15Ra and a transmembrane domain of a heterologous molecule. In addition, described herein are methods for propagating, activating and/or differentiating IL-15 responsive cells, comprising co-culturing an IL-15 responsive cell(s) with a host cell(s) that recombinantly expresses IL-15Ra, and isolating the IL-15 responsive cell(s) from the host cell(s). The IL-15 responsive cells that are immune cells can be administered to prevent, treat and/or manage various disorders, including cancer, an infectious disease, an immunodeficiency and lymphopenia. Further, described herein are methods of enhancing IL-15 -mediated immune function as well as methods for preventing, treating and/or managing disorders in which enhancing IL- 15- mediated function is beneficial, such as cancer, in a subject, the methods comprising administering to the subject a host cell that recombinantly expresses an IL-15Ra described herein.
Patent EP-2805873-A2 (EP)
Inventor: BICKEL THOMAS J
IPC: B62D5/04
Filed: 2014-05-02
Abstract: A redundancy system for a steering system having a primary controller (106) and a primary power source (108) is provided. The redundancy system includes a secondary controller (110) coupled to a secondary power source (112) and configured to manage control of the steering system, and an interface circuit (114) disposed between at least a first node (116) and a second node (118). The first node (116) is in electrical communication with the primary power source (108), and the second node (118) is in electrical communication with the secondary power source (112). The interface circuit (114) is configured to selectively engage a self-test of the primary power source (108) and the secondary power source (112), isolate a short at the first node (116) from the secondary power source (112), and isolate a short at the second node (118) from the primary power source (108).
Patent EP-2732994-A2 (EP)
Inventor: KIM JONGSU
IPC: B60H1/00
Filed: 2011-09-02
Abstract: The present invention relates to an air conditioner for a vehicle, which includes: a scroll case (120); a centrifugal fan (145) rotatably mounted inside the scroll case; an intake duct (150) aligned on one side of the scroll case (120) in an axial direction of the centrifugal fan (145); and a motor housing (140) coupled to the other side of the scroll case, the air conditioner comprising: a connection cover (130) coupled to one side of the scroll case (120) for connecting the intake duct (150) and the scroll case with each other; and including: an inlet ring (131) formed on an end portion thereof to guide the air introduced through the intake duct (150) to the inside of the centrifugal fan (145); and a dual ring (132) formed on the circumference of the inlet ring (131) and adapted to prevent a re-introduction of the air to the centrifugal fan.
Patent EP-2779473-A2 (EP)
Inventor: PRATT PATRICK
IPC: H04B1/52
Filed: 2014-03-06
Abstract: Transmitter noise cancellation may be applied on a channel by channel basis to active channels of an incoming radio frequency signal received at a receiver. A noise cancellation filter may be provided for each active channel in a predetermined signal band. Applying noise cancellation on a per active channel basis instead of to the entire receive band may substantially reduce the filtering requirement and number of filter coefficients or taps to save power and reduce manufacturing costs. Channelized transmitter noise cancellers, multi transmitter-receiver cross coupling cancellers, and hybrid full signal band and channelized transmitter noise cancellers are also provided.
Patent EP-2818767-A2 (EP)
Inventor: HOTEI TAKASHI
IPC: F16H63/18
Filed: 2014-03-06
Abstract: Two projection rows 98, 99 which are objects to be detected by two specified switches SB, SC; SA, SC among the three switches SA to SC are formed so as to change switching modes of the specified switches SB, SC; SA, SC from an OFF state to an ON state and to displace timings at which the specified switches are brought into an ON state from each other when a shift position is changed from at least one of a first speed position and a second speed position to a neutral position.
Patent EP-2778535-A2 (EP)
Inventor: HUTTUNEN JANNE
IPC: F24B9/00
Filed: 2014-03-14
Abstract: The invention relates to a heat recovery chimney (10) which comprises a flue pipe (11) for connection to a fireplace and a jacket pipe (12) fitted around the flue pipe so that the flue pipe (11) and the jacket pipe (12) delimit an annular water space. The water space is closed by end pieces (16) at both ends in the direction of the length of the chimney (10) to form a closed space. Heat-storing fluid is circulated in the water space and receives heat produced by flue gas directly from the flue pipe (11), from which fluid the heat is arranged to be utilized. A flow channel (13) is fitted inside the water space of the heat recovery chimney (10) and extends substantially from the bottom end of the water space to the top end thereof, to one end of which flow channel an inlet coupling (17) is connected to supply circulation fluid to the flow channel (13). The circulation fluid is discharged through the opposite open end of the flow channel (13) into the water space from which it is utilized through a fluid outlet coupling (18) connected to the jacket pipe (12) at the same end of the water space in the direction of the length of the heat recovery chimney (10) as the inlet coupling (17).
Patent EP-2806530-A2 (EP)
Inventor: KANAI YASUYUKI
IPC: H02M3/156
Filed: 2004-07-07
Abstract: A booster circuit (12) generates a boosted output by boosting a low voltage output supplied as a target to be boosted and feeds back a part of the boosted output, an output by the booster circuit itself, to the booster circuit as operation energy. An auxiliary booster circuit (13) outputs start-up energy generated based on a low voltage output to the booster circuit (12) as start-up energy that is necessary for starting up the booster circuit (12).
Patent EP-2868856-A2 (EP)
Inventor: JEANJEAN JULIEN
IPC: E06B3/972
Filed: 2014-11-04
Abstract: Die vorliegende Erfindung betrifft einen Eckverbinder (100, 200, 300) zum Verbinden auf Gehrung geschnittener Hohlprofile (1, 2) eines Fenster- oder Türrahmens. Um eine spielfreie Verbindung des Eckverbinders (100, 200, 300) mit den Hohlprofilen (1, 2) zu gewährleisten, ist es erfindungsgemäß vorgesehen, dass der Eckverbinder (100, 200, 300) von einem ersten Zustand, in welchem die beiden Schenkel (110, 120, 210, 220, 310, 320) in die jeweiligen Innenräume (4, 5) der Hohlprofile (1, 2) einführbar und herausnehmbar sind, in einen zweiten expandierten Zustand, in welchem die beiden Schenkel (110, 120, 210, 220, 310, 320) kraftschlüssig mit den jeweiligen Hohlprofilen (1, 2) verbunden sind, überführbar ist.
Patent EP-3039561-A2 (EP)
Inventor: BAKAEV ALEXANDER
IPC: G06F15/16
Filed: 2014-07-22
Abstract: A technique for joining a web conference on a mobile device includes running a program on the mobile device that displays a list of web conference invitations for web conferences scheduled to be held at or near the current time, receiving a user selection of one of the listed web conference invitations, and initiating a web conference for the selected web conference invitation using a web conference client installed on the mobile device. The technique enables mobile users to join web conferences quickly and with few manual operations.
Patent EP-2996938-A2 (EP)
Inventor: FUJINO MICHIMASA
IPC: E06B5/12
Filed: 2014-05-14
Abstract: An aircraft includes a fuselage including a plurality of frame members disposed at predetermined intervals in a longitudinal direction of the fuselage and a plurality of stringers extending substantially linearly in the longitudinal direction. The fuselage defines an aircraft interior. A compartment is located in the interior of the fuselage. The compartment defines an interior area. A first one window assembly is mounted to an upper portion of the fuselage for introducing daylight into the interior area. The first window assembly is flanked by adjacent frame members of the plurality of frame members and adjacent stringers of the plurality of stringers. The first window assembly includes a window pane, an inner cover and a retainer. The inner cover introduces daylight from the window pane into the interior area. The retainer secures the window pane and the inner cover to the fuselage.
Patent EP-2988105-A2 (EP)
Inventor: HEINTZ FRANK
IPC: G10L25/51
Filed: 2015-08-18
Abstract: Um ein Verfahren zur automatischen Erkennung und Klassifizierung von hörbaren akustischen Signalen in einem Überwachungsbereich derart auszugestalten, dass bei der Konfiguration durch den Anwender alle signalbeeinflussenden Faktoren mit in das jeweilige Erkennungsmodell einfließen, ist vorgesehen, dass zur Vorverarbeitung der akustischen Signale ein akustisches Sensorsystem (2) vorgesehen ist, welches mit einem Signalempfänger (1) in Verbindung steht, dessen Ausgangssignale parallel einem im akustischen Sensorsystem (2) angeordneten Modul für deren Aufzeichnung (3) und einem Modul zur Klassifizierung (4) zugeführt sind, dass mit dem Aufzeichnungs-Modul (3) eine Aufzeichnungsdatenbank (5) des akustisches Sensorsystems (2) verbunden ist, in welcher das Signal im Format einer Audiodatei gespeichert ist, dass zum Datenaustausch und zur Steuerung mit dem eine Schnittstelle (S1, S2) aufweisenden akustischen Sensorsystems (2) ein Modul zur Modellbildung (7) in Verbindung steht, welches über die Schnittstelle (S1,S2) die Aufzeichnungen importiert, aus ihnen entsprechende Modelle erzeugt und welches über die Schnittstelle (S1, S2) mit einer Modellbibliothek (6) des entsprechenden Sensorsystems (2) in Verbindung steht, in welcher das von einem Anwender in einer Trainingsphase ausgewählte Modell abgespeichert ist, dass das Klassifizierungs-Modul (4) mit der Modellbibliothek (6) verbunden ist und dass das Klassifizierungs-Modul (4) über eine weitere Schnittstelle (S3) mit einer Auswertungs-Applikation (8) in Verbindung steht, und für den Fall der Erkennung eines Signal, das Klassifizierungsergebnis an die Auswertungs-Applikation (8) sendet, so dass das akustische Sensorsystem (2) gleichermaßen als Aufzeichnungssystem für beliebige akustische Signale während einer Trainingsphase, als auch als Klassifikator (4) bekannter Signalmuster während einer Klassifizierungsphase dient und die dafür notwendigen Erkennungsmodelle aus den von dem Sensorsystem (2) vorher aufgezeichneten Signalen erzeugt und diese Modelle danach auch nur von diesem Sensorsystem (2) zur Klassifizierung eingesetzt werden.
Patent EP-3108661-A2 (EP)
Inventor: RAI PETE
IPC: H04H60/56
Filed: 2015-02-19
Abstract: Selon un mode de réalisation de la présente invention, un procédé mis en œuvre sur un dispositif informatique et permettant de déduire des métadonnées temporelles pour un contenu vidéo, consiste : à capturer des éléments temporels grâce à l'analyse d'au moins un aspect parmi un aspect audio, un aspect visuel et un aspect linguistique du contenu vidéo ; à interpréter, en fonction de déductions associées, les éléments temporels comme étant des états temporels ; à évaluer des combinaisons des états temporels conformément à un ensemble de règles afin de déduire des métadonnées temporelles, ces métadonnées temporelles étant associées à au moins une partie du contenu vidéo.
Patent EP-3137649-A2 (EP)
Inventor: ATTHOFF BJÖRN
IPC: H05K3/18
Filed: 2015-04-28
Abstract: There is disclosed a method for application of a metal on a substrate, comprising the steps: a) contacting at least a part of the surface of the substrate with at least one selected from: i) at least one initiator, and a polymerizable unit with the ability to undergo a chemical reaction to form a polymer, said polymer comprising at least one charged group, and ii) a polymer comprising at least one charged group. The contacting is achieved by contacting a pad with a plate comprising the at least one substance and subsequently contacting the pad with the surface of the substrate, thereby transferring the at least one substance to the surface of the substrate. Subsequently a metal layer is produced on the surface. Advantages include that the compactness of the applied metal layer increases compared to similar methods according to the prior art.
Patent EP-3160691-A2 (EP)
Title: Manipulator mit einem manipulatorarm
Inventor: PIDAN SERGEJ
IPC: B25J15/00
Filed: 2015-06-30
Abstract: Die Erfindung betrifft einen Manipulator mit einem Manipulatorarm (5), an dessen, einem freien Ende (6) ein Manipulatorflansch (8) vorgesehen ist, an dem ein Endeffektor (46) mit einer Applikationsvorrichtung (9) zur Bearbeitung eines Werkstücks (37) gehalten ist. Der Manipulatorflansch (8) ist um Handachsen (20, 21, 22) drehbar. Eine erste Handachse (20) erstreckt sich in Richtung der Längsachse (18) des Manipulatorannes (5), eine zweite Handachse (21) erstreckt sich quer zur ersten Handachse (20) und eine dritte Handachse (22) erstreckt sieh quer zur zweiten Handachse (21), wobei sich, die Handachsen (20, 21, 22) in einem gemeinsamen Schnittpunkt (26) schneiden. Eine auf die Applikationsvorrichtung (9) wirkende Bearbeitungskraft (33) ist über den Endeffektor (46) in den Manipulatorarm (5) abgeleitet. Damit bei einer mechanischen Arbeit auftretende Prozesskräfte nicht zu einer Beeinträchtigung der Bearbeitungspose des Manipulatorarms (5) führen, ist vorgesehen, die Applikationsvorrichtung (9) unter einem Anbindungswinkel (30) zur ersten Handachse (20) an dem Manipulatorflansch (8) festzulegen, derart, dass eine an der Applikationsvorrichtung (9) auftretende Bearbeitungskraft (33) in einer Richtung (31) auf den. Manipulatorarm (5) abgeleitet ist, die durch den Schnittbereich (25) der Handachsen (20, 21, 22) verläuft.
Patent EP-3195331-A2 (EP)
Title: Nanoparticules pour des applications d'imagerie par résonance magnétique
Inventor: WEI HE
IPC: H01F1/00
Filed: 2015-09-10
Abstract: L'invention concerne un procédé de préparation d'une nanoparticule revêtue qui consiste à décomposer un composé pour produire une nanoparticule, à oxyder la nanoparticule pour produire une nanoparticule oxydée, et à enrober la nanoparticule oxydée d'un ligand zwitterionique pour produire la nanoparticule enrobée. La nanoparticule ou la nanoparticule enrobée peut être utilisée dans l'imagerie par résonance magnétique.
Patent EP-3165154-A2 (EP)
Inventor: HEIKENFELD JASON C
IPC: A61B18/12
Filed: 2014-10-17
Abstract: A sweat sensing device (28) includes a plurality of sweat collection pads (40, 42, and 44) communicating with a sensor (36). Each of the pads (40, 42, and 44) is activated by electronics (34) that include a timing circuit which allows one or more of the pads (40, 42, and 44) to be activated at a selected time and subsequent deactivated after a defined period of time. This allows for selective collection of sweat from a plurality of pads over a prolonged period of time. Further, the devices can use a common microfluidic device (38) which both transports sweat activating substance, such as pilocarpine, to the surface of the skin (12) and directs sweat away from the skin (12) to a sensing device (28).
Patent EP-3383876-A2 (EP)
Inventor: ZANG LING
IPC: C09B5/62
Filed: 2016-12-02
Abstract: L'invention concerne un composé de capteur de vapeur chimiorésistif qui est destiné à la détection de vapeurs cibles et qui peut comprendre un noyau de pérylène tétracarboxylique diimide (PTCDI) selon la structure (I), où R peut être un groupe de régulation de morphologie ou -A'-D', A et A' peuvent être indépendamment un groupe de liaison, D et D' peuvent être indépendamment un donneur d'électrons puissant qui transfère des électrons au noyau PTCDI de façon suffisante pour former un radical PTCDI anionique du noyau PTCDI, et R1 à R8 peuvent être indépendamment un groupe latéral. Un capteur de vapeur chimiorésistif (100) destiné à la détection d'un composé cible peut comprendre un ensemble de nanofibres (105) formées du composé de capteur chimiorésistif et une paire d'électrodes (150A, 150B) orientées fonctionnellement autour de l'ensemble de nanofibres (105) pour permettre au courant électrique de passer d'une première électrode de la paire d'électrodes (150A, 150B) à travers l'ensemble de nanofibres (105) et à une seconde électrode de la paire d'électrodes.
Patent EP-3318208-A2 (EP)
Inventor: CASTANEDA ALFREDO
IPC: A61B17/80
Filed: 2012-12-13
Abstract: A volar distal radius plate includes a shaft and a head. The head includes a radial side that seats below the volar rim, and an ulnar side with two extending tabs that provide a buttress support to ulnar fragments from the volar rim. The tabs are contoured to be atraumatic to the overlying soft tissue. The tabs can be readily re- orientated to better approximate the volar rim and provide close support to the volar fragments. Each tab includes a single hole specifically sized to closely receive a K- wire in a fixed angle orientation, and which permits the K-wire to apply a bending load to a tab in situ to bend the tab about a lower recess between the tab and the remainder of the head. Therefore, the plate does not require a dedicated bender. The tabs can also accommodate sutures.
Patent EP-3261024-A2 (EP)
Inventor: COMANICIU DORIN
IPC: G06N3/02
Filed: 2017-06-01
Abstract: A method and apparatus for vascular disease detection and characterization using a recurrent neural network (RNN) is disclosed. A plurality of 2D cross-section image patches are extracted from a 3D computed tomography angiography (CTA) image, each extracted at a respective sampling point along a vessel centerline of a vessel of interest in the 3D CTA image. Vascular abnormalities in the vessel of interest are detected and characterized by classifying each of the sampling points along the vessel centerline based on the plurality of 2D cross-section image patches using a trained RNN.
Patent EP-3298972-A2 (EP)
Inventor: ROSSNEY MARK
IPC: A61B17/17
Filed: 2017-09-19
Abstract: Intramedullary nails, systems, and methods. The intramedullary nail may include a generally elongate body extending from a first, distal end to a second, proximal end. The distal end may include one or more openings configured to receive one or more bone anchors that extend transversely through the distal end intramedullary nail, and thereby configured to secure the distal end of the nail. The proximal end may also include one or more openings configured to receive one or more bone anchors that extend transversely through the proximal end of the intramedullary nail, and thereby configured to secure the proximal end of the nail. In some embodiments, the proximal end may further include a cross-locking feature, which includes a second bone anchor that interlocks with a first bone anchor, for example, for enhanced bone purchase and bony fixation.
Patent EP-3454360-A2 (EP)
Inventor: YAMAGUCHI TADASHI
IPC: H01L27/088
Filed: 2018-08-23
Abstract: A memory gate electrode and a control gate electrode are formed to cover a fin projecting from the upper surface of a semiconductor substrate. A part of the fin which is covered by the memory gate electrode and the control gate electrode is sandwiched by a silicide layer as a part of a source region and a drain region of a memory cell. This silicide layer is formed as a silicide layer.
Patent EP-3483914-A2 (EP)
Inventor: FUKUDA TOMOHISA
IPC: H01J37/244
Filed: 2018-11-07
Abstract: A charged particle beam device includes: a detection chamber flange 140; a detector 30; a detector holding stand 110 which holds the detector; a first shaft 120 which is slidably inserted into a guide hole 144 and connected to the detector holding stand, the guide hole being provided in the detection chamber flange. 
     The device may further include a first flange 170 which is attached to the detection chamber flange and has a spherical bearing; a second flange180 which is supported by the spherical bearing of the first flange; and a second shaft 122 which is slidably inserted into a guide hole 182 provided in the second flange and passes through a through-hole 146 in the detection chamber flange to be connected to the detector holding stand, each of the first shaft and the second shaft being provided with a flow channel 121,122 of a heat transfer medium for cooling or heating the detector.
Patent EP-3656106-A2 (EP)
Title: Systems and methods for packet spreading data transmission with anonymized endpoints
Inventor: JONES MICHAEL T
IPC: H04W12/02
Filed: 2018-07-19
Abstract: A packet-spreading data transmission system with anonymized endpoints facilitates enhanced fortified private communications between a plurality of arbitrary devices via a plurality of communication channels or networks. The data transmission system receives at a source endpoint device a message of arbitrary length. The message includes a destination address associated with a destination endpoint device. Both source endpoint device and the destination endpoint device are selected from a plurality of arbitrary devices. The received message are fragmented and agilely transmitted, via a plurality of communication channels, from the source endpoint device to the destination endpoint device.
Patent EP-3502648-A2 (EP)
Inventor: LAWSON LAWRENCE J
IPC: G01L5/16
Filed: 2014-07-10
Abstract: A balancing device (10b), a uniformity device (10u) and an apparatus (10", 10'''') including the balancing device (10b) and the uniformity device (10u) are disclosed. Each of the balancing device (10b) and the uniformity device (10u) includes at least one multi-axis transducer (50b, 50b', 114u a ) or three or more air spring members (114u b ). Methods are also disclosed.
Patent EP-3550804-A2 (EP)
Inventor: YEUNG MICHAEL
IPC: G06F11/07
Filed: 2019-02-22
Abstract: A system and method for paper jam prediction includes a processor, memory and a network interface. Ongoing paper jam data is received from an identified, networked multifunction peripheral. Service call data for the multifunction peripheral indicative of prior service calls is stored in the memory. A sampling window of the paper jam data prior to a service call date is defined and a point in the sampling window when no symptoms of a forthcoming paper jam were present is determined so as to define a prediction window. A relationship between paper jam data in the prediction window of the sampling window and paper jam data outside the prediction window in the sampling window is determined and incoming paper jam data is monitored relative to the relationship data. A paper jam warning is generated when monitored incoming paper jam data indicates a forthcoming paper jam on the multifunction peripheral.