baber/WOPTO huggingface dataset:
Patent DE-60334676-D1 (DE)
Inventor: GRIGNANI ANDREA
IPC: A61L31/08
Filed: 2003-02-21
Granted: 2010-12-09
Abstract: A process for making, on regions (12) of the surface of a stent (1), a deposit of an active substance (M), comprises: 
- providing the active substance (M) in at least one form chosen between a powder and a paste; and 
- depositing the active substance (M) on said regions (12) of the surface of the stent (1).  Preferably, the active substance (M) substantially consists of FK506, such as FK506 in the form of a powder with a grain size smaller than 15 micron or a paste with a base of FK506 with a viscosity not lower than 100,000 - 120,000 cps.
Patent DE-60335608-D1 (DE)
Inventor: BOLOTIN ELIJAH M
IPC: A61K9/12
Filed: 2003-02-27
Granted: 2011-02-17
Abstract: In part, the present invention is directed to biocompatible compositions comprising a carrier with a first metal binding domain, a metal ion, an active agent with second metal binding domain and optionally a protective chain covalently attached to the polymeric carrier.
Patent DE-68908963-D1 (DE)
Inventor: WAITE PETER DONALD
IPC: C22B21/06
Filed: 1989-06-09
Granted: 1993-10-14
Abstract: An apparatus and process are described for treating molten metal. The invention comprises: (a) a heated vessel (10) having inlet (11) and outlet (12) means for the continuous flow of molten metal downwardly through the vessel (10), (b) a perforated plate (16) extending horizontally across the vessel dividing it into an upper treatment section and a lower treatment section, this plate forming an intermediate treatment section, and (c) a device for injecting gas in the form of small discrete bubbles into the metal in the lower treatment section, this device comprising a hollow rotatable shaft (20) extending downwardly through an opening (30) in the plate (16) with drive means coupled to the upper end of the shaft (20), a vaned rotor (22) fixedly attached to the lower end of the shaft within the lower treatment section, with one or more passageways within the rotor for conducting gas from the interior of the shaft to the metal in the lower treatment section. When the gas is discharged through the rotor (22) and the rotor (22) is rotated, the gas is injected into the metal in the form of small discrete bubbles (61) which are uniformly dispersed within the lower treatment section. In a preferred embodiment of the invention the gas bubbles move from the rotor upwardly and outwardly in a generally conical pattern (60) to be distributed across the bottom of the perforated plate (16) and pass upwardly through the perforations thereof.
Patent DE-68912362-D1 (DE)
Inventor: KAPLAN ZVI
IPC: F41F1/00
Filed: 1989-03-01
Granted: 1994-03-03
Abstract: A method and apparatus for accelerating a projectile in a launching tube at a rate determined by the rate of combustion of a propellant charge (3-6, 34) disposed within the tube at the rear of the projectile. The method includes the steps of:      generating an electrical discharge for producing hot gases, and injecting the hot gases into a region of the launching tube in the rear of said projectile so as to interact with said propellant charge, thereby increasing its rate of combustion.
Patent DE-68928130-D1 (DE)
Inventor: WANG CHANG YI
IPC: A61K39/21
Filed: 1989-02-10
Granted: 1997-07-24
Abstract: This invention relates to a method using synthetic peptides as solid phase immunoadsorbents for the detection of antibodies to Human Immunodeficiency Virus (HIV) gp120, and, in particular, antibodies having HIV neutralizing capabilities. The amino acid sequences of the peptides correspond to segments of the external envelope protein gp120 of HIV. These peptides have been found to be highly immunogenic, and are reactive with antibodies in sera of patients with AIDS, ARC or HIV infected individuals. They can also be used to elicit the production of neutralizing antibodies to HIV. More specifically, the present invention is directed to the use of a synthetic peptide selected from the groups consisting of peptides containing twenty-eight and thirty-three amino acids in a prescribed sequence, their analogues and mixtures, corresponding to the HIV-gp120 external protein for the detection of antibodies to HIV-gp120. It is particularly useful for the dectection of antibodies having HIV neutralizing capabilities. The detection method includes an enzyme linked immunoassay and other forms of immunoassay procedures. The present invention also relates to a method for generating high titer antibodies to HIV gp120 protein in healthy mamals, including humans, by the use of the synthetic peptides, their analogues or mixtures in either a conjugated or a polymeric form as a key component in a synthetic vaccine for the prevention of AIDS.
Patent DE-69006860-D1 (DE)
Inventor: SUEHIRO MITSUGI
IPC: B01D53/34
Filed: 1990-01-04
Granted: 1994-04-07
Abstract: Disclosed are, in a method for purifying a high-temperature reducing gas in which sulfur compounds present in a high-temperature reducing gas are absorbed and removed by an absorbent according to a dry method, a method for purifying a high-temperature reducing gas which is characterized in that a reducing gas is supplied into a gas containing sulfurous acid gas which is discharged from a regeneration system for regenerating the absorbent which system forms a system together with an absorption system in which the sulfur compounds are absorbed with the absorbent, a resulting gas mixture is led through a reactor filled with a catalyst, the sulfurous acid gas and the reducing gas are let react with each other under pressurization so that simple sulfur is directly produced and collected as liquid sulfur; and the above method which is further characterized in that catalyst layers in the reactor in which the sulfurous acid gas and the reducing gas react with each other are divided into parts or made to have a plurality of stages, a heat exchanger and a sulfur condenser are disposed between these parts or stages, and the temperature control of these gases and the removal of sulfur produced in the reaction are carried out during the reaction.
Patent DE-69007013-D1 (DE)
Inventor: METERKO TIMOTHY A
IPC: C08G73/10
Filed: 1990-10-18
Granted: 1994-04-07
Abstract: Polyimide copolymers of the following formulas are disclosed: The first is a copolyimide of the recurring structure <CHEM> wherein AR may be either AR1 or AR2, wherein AR1 is represented by the following formula: <CHEM>  and wherein AR2 is represented by the following formula: <CHEM> provided that the molar ratio between AR1 and AR2 is in the range from 3:1 to 1:3 and wherein AR3 is selected from the group consisting of <CHEM>   The second is a block copolyimide in which the following two recurring structures exist as blocks wherein block 1 is <CHEM>  where AR1 is <CHEM>  and wherein block 2 is <CHEM>  where AR2 is <CHEM> provided that the molar ratio of block 1 to block 2 is in the range of 3:1 to 1:3 and wherein AR3 is selected from the group consisting of <CHEM>   These polyimides have unexpected properties which are useful in various electronic applications.
Patent DE-69014308-D1 (DE)
Inventor: BONNE ULRICH
IPC: F23N1/02
Filed: 1990-10-09
Granted: 1995-01-05
Abstract: In a combustion system, fuel flow and fuel composition are sensed, and energy flow in the combustion system is determined based on the fuel flow and the fuel composition. Air flow of combustion air is also sensed. The fuel-to-air ratio in the combustion system is controlled as a function of the energy or oxygen demand flow determined and the air flow sensed.
Patent DE-69016241-D1 (DE)
Inventor: FAURE JEAN-FRANCOIS
IPC: C22C21/10
Filed: 1990-04-03
Granted: 1995-03-09
Abstract: Al-based alloys of the 7000 series which have a high modulus (E >/= 74 GPa), a high mechanical strength (R0.2 >/= 530 MPa in the lengthwise direction), a good tenacity (KIC, lengthwise direction > 20 MPa  2ROOT m) and a good corrosion resistance under (O pressure >/= 250 MPa in the short transverse direction, lifetime >/= 30 days - ASTM Standard G 38-73). 
<??>The alloy according to the invention corresponds to the following weight composition:
 from 5.5 to 8.45% of Zr
 from 2 to 3.5% Mg
 from 0.5 to 2.5% Cu
 up to 0.5% Fe
 up to 0.5% Si
 other elements </= 0.05% each
 and up to 0.15% in all
 with
 0.1 </= Zr </= 0.5%
 0.3 </= Cr </= 0.6%
 0.3 </= Mn </= 1.1%
 
<??>It is preferably produced by the following process:
 a) a massive body which has the composition claimed above is formed by spray-deposition,
 b) this body is converted into a wrought product between 300 and 450 DEG C and then optionally when cold
 c) the wrought product is heat-treated by dissolving, quenching and annealing to a T6 or T7 state. 
<IMAGE>
Patent DE-69103096-D1 (DE)
Inventor: CANZIANI FRANCESCO
IPC: B65G1/04
Filed: 1991-03-08
Granted: 1994-09-01
Abstract: The unit includes an overhead line (1) along which a large number of trollies or sorting containers move. Each is provided with a moving base like a small rotating mat (10) enabling collection and depositing of packages to be sorted along the line (1). Each of these bases is mounted onto its respective trolley by way of a telescopic structure (8) and along the line (1) there are mechanisms to position each cell at a height corresponding to that of the collection devies where the packages are to be unloaded.
Patent DE-69112402-D1 (DE)
Inventor: UNGER PETER
IPC: A61M5/14
Filed: 1991-06-26
Granted: 1995-09-28
Abstract: The present invention relates to a method and to a device for separating blood present in a blood container (1) into components (34, 36, 35) by centrifuging the blood, and for transmitting at least one of three stratified components (34, 35) obtained by centrifugation in sterile fashion to a respective side container (2, 3) connected to the blood container (1) via a respective hose (4, 5). The fluid-actuatable displacement body (17) and the blood container (1) are placed in a cassette (12, 13) which, in turn, can be placed in a centrifuge cup (25). The displacement body (17) is in direct abutment with the blood container (1). The displacement body (17) surrounds half the blood container (1) and when fluid is delivered to the body, it will preferably expand, firstly at its lower part and then successively upwards. The cassette (12, 13) is preferably placed in one of two compartments (27) of an intermediate container (24), the other compartment (41) being intended to accommodate the side container (2 and 3 respectively).
Patent DE-69112637-D1 (DE)
Inventor: TAYLOR ANTHONY JAMES
IPC: A61K9/12
Filed: 1991-11-07
Granted: 1995-10-05
Abstract: Aerosol formulations comprising: (A) a medicament in particulate form and having a surface coating of a surfactant; (B) a hydrogen-containing fluorocarbon or chlorofluorocarbon propellant; and (C) a cosolvent having higher polarity than the propellant which cosolvent is present in an amount of up to 5 % w/w based upon propellant; and methods for their preparation.
Patent DE-69113806-D1 (DE)
Inventor: PARKER JEFFREY
IPC: G01B11/30
Filed: 1991-08-09
Granted: 1995-11-16
Abstract: This invention is a surface inspection system including a light source having a sharp edge between dark and bright and a video camera imaging this edge reflected from the surface. The light intensity of the light source is controlled using a light intensity sensor. An optical system focusses an image of the light source at the video camera with sufficient depth of focus to include the surface to be inspected. The exposure duration is set to prevent blurring if the surface to be inspected is moving. A surface quality computation apparatus computes at least one measure of surface quality, such as gloss, distinctness of reflected image and orange peel of the surface, from the video image signal. This surface quality computation apparatus preferably includes a frame grabber and a general purpose digital computer. Gloss is computed by determination of the maximum and minimum brightness slopes of the video image signal of the edge. Distinctness of reflected image is similarly computed and then corrected for the difference between the maximum brightness and minimum brightness of the video image signal. Orange peel is computed by determination of the periodicity variations of the positions of maximum and minimum brightness slope in the video image signal of the edge.
Patent DE-69115274-D1 (DE)
Inventor: YOSHINO AKIRA
IPC: C23C8/80
Filed: 1991-09-20
Granted: 1996-01-18
Abstract: An austenitic stainless steel screw having excellent non corroding properties and a high level of hardness is disclosed, together with a method for manufacture of such screws. A hard nitrided layer is formed on the surface of the austenitic stainless steel screw, and the nitrided layer is removed over predetermined parts such as the head and part of the shank of the screw.
Patent DE-69118189-D1 (DE)
Inventor: MOSCATTINI FEDERICO
IPC: B65G57/18
Filed: 1991-12-04
Granted: 1996-04-25
Abstract: The object of this invention is to provide a bar layers preparation method for packing plants, starting from bar layers which are caused to advance transversely in alternating number "n-1" and "n", of the kind utilizing:   a first overturning transfer system from above of one bar layer on the other (3-31-32) in order to form a double bar layer, the one upright and the other reverse, in association with: a second always from above transfer system (4-41), in order to transport said two superposed bar layers to a packing pocket (6), wherein the formation of said double bar layer is carried out through pick-up of one downward bar layer (F4) in order to carry it turned over the upward layer (F3). <IMAGE>
Patent DE-69120890-D1 (DE)
Inventor: MAYO SUSAN
IPC: C12N15/09
Filed: 1991-04-29
Granted: 1996-08-22
Abstract: Human lymphoid tissue is introduced into an immunocompromised host to provide opportunities to investigate the effect of stimuli on the human immune system and obtain information and products for the stimulus. Particularly, methodology is provided for the production of human monoclonal antibodies by introducing lymphoid tissue into an immunocompromised host, stimulating the B-lymphocytes with an appropriate immunogen, harvesting the tissue and immortalizing and/or cloning the B-lymphocytes under conditions to obtain a stable supply of monoclonal antibodies.
Patent DE-69124223-D1 (DE)
Inventor: SLAGA THOMAS
IPC: A23L1/305
Filed: 1991-02-04
Granted: 1997-02-27
Abstract: The present invention concerns a formulation of vitamins, minerals and other beneficial supplements. It is believed that the formulations of the present invention will not only extend longevity but also protect against diseases such as certain cancers and cardiovascular disorders as well as to facilitate immunological integrity in humans. More specifically, the invention is directed to a formulation and methods of manufacturing and administering a formulation containing vitamins and minerals in association with antioxidants, fish oils, enzymes, and amino acids. The formulations of the present invention provide synergistic relationships which have not previously been reported. As a preferred embodiment, the formulations of the present invention are manufactured as a sustained-release tableted dietary supplement and are intended as daily supplements.
Patent DE-69126535-D1 (DE)
Inventor: HUBBELL JEFFREY
IPC: A61K9/50
Filed: 1991-09-25
Granted: 1997-07-17
Abstract: This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as a "glue" to cause more than one biological substance to adhere together, or as carriers for biologically active species. Several methods for forming these membranes are provided. Each of these methods utilizes a polymerization system containing water-soluble macromers, species, which are at once polymers and macromolecules capable of further polymerization. The macromers are polymerized using a photoinitiator (such as a dye), optionally a cocatalyst, optionally an accelerator, and radiation in the form of visible or long wavelength UV light. The reaction occurs either by suspension polymerization or by interfacial polymerization. The polymer membrane can be formed directly on the surface of the biological material, or it can be formed on material, which is already encapsulated.
Patent DE-69132109-D1 (DE)
Inventor: HENDRICKSON ALAN F
IPC: H04M1/60
Filed: 1991-08-09
Granted: 2000-05-18
Abstract: A method for operating an apparatus for facilitating communications between an analog device and a digital device, which apparatus includes a plurality of signal processing circuits and a control circuit for controlling the signal processing circuits. Each of the signal processing circuits includes signal attenuators and signal burst discrimination circuitry. The apparatus is operable in a plurality of stable states, preferably in an idle stable state, a transmit stable state, and a receive stable state. The apparatus also is operable in a plurality of transitional states, including up-transition states and down-transition states. The method includes the steps of evaluating each of the signal processing circuits by the signal burst discrimination circuitry, responding to detection of a burst indicator by setting a state indicator to an appropriate up-transition state, incrementally adjusting the attenuators in the signal processing circuits to enhance performance of the apparatus until the attenuators are at predetermined settings, periodically checking for presence of the burst indicator, on detection of cessation of the burst indicator, setting the state indicator to an appropriate down-transition state, incrementally adjusting the attenuators to redistribute attenuation losses among the signal processing circuits, if no burst indicator is detected, continuing such redistribution until the apparatus returns to the idle stable state.
Patent DE-69203291-D1 (DE)
Inventor: BISHOP PETER TRENTON
IPC: C07F1/12
Filed: 1992-05-06
Granted: 1995-08-10
Abstract: A homogeneous compsn. for forming, on firing, a film of precious metal (I) selected from one or more of platinum, palladium, gold and silver, onto a substrate (II). The compsn. comprises: (i) polymeric resin (III); and (ii) a soln., in water and a co-solvent (IV), of a thiolate of (I). The compsn. contains 3-22 wt.% of (I) as the thiolate. (III), (IV) and the thiolate are such, that as the compsn. (on a substrate (II) dries and is progressively heated in firing, the water evaporates to leave a homogeneous compsn. of (III) and thiolate in the cosolvent (IV); subsequently, (IV) evaporates to leave a homogeneous compsn. of the thiolate in (III); finally, the thiolate decomposes to (I) while the resin (III) violatilises. Firing is carried out at 460-900 deg.C. The compsn. produces a bright film on firing. The compsn. can opt. contain precious metal powder or insoluble precious metal cpd. to produce a burnished film on firing which is subsequently burnished. Alternatively, the compsn. opt. contains an insol. matting agent to produce a self-burnishing film on firing.
Patent DE-69222516-D1 (DE)
Inventor: SOMMER ROLAND
IPC: A63B53/00
Filed: 1992-07-26
Granted: 1997-11-06
Abstract: PCT No. PCT/EP92/01697 Sec. 371 Date May 20, 1993 Sec. 102(e) Date May 20, 1993 PCT Filed Jul. 26, 1992 PCT Pub. No. WO93/02753 PCT Pub. Date Feb. 18, 1993.Sports equipment for ball games comprising a stroke portion and a shaft portion including a grip, in particular a tennis racket or a golf club, wherein mass particles are integrated into the equipment structure which are freely displaceable or freely movable thereto and which are provided in one or a plurality of chamber(s) the volume of each of said chambers being small relative to the interior volume of the stroke and/or the shaft portion. The stroke characteristics of the sports equipment can be variied depending from the distribution of the chambers within the structure and/or from the amount of the mass particles used. Stroke shocks are attenuated with the result that occurrence of "tennis elbow" is diminished.
Patent DE-69222855-D1 (DE)
Inventor: WALKER ROBERT
IPC: F01M13/02
Filed: 1992-07-29
Granted: 1997-11-27
Abstract: The combination apparatus silences and filters air flow and separates air-contaminant mixtures. An air filter joins an annular housing which has an outer wall and a channel defining a central axis, the channel having a primary gas inlet coupled to the air filter and a primary gas outlet and a channel wall. The apparatus has a secondary inlet port passing through the outer wall. A secondary outlet port defines an opening in the channel wall such that there is no straight line flow path between the secondary inlet and the secondary outlet. An air silencer is contained within the channel. A passageway between the secondary inlet and the secondary outlet is defined exteriorly by the outer wall and interiorly by the channel wall.
Patent DE-69230730-D1 (DE)
Inventor: DAUBIE CHRISTOPHE
IPC: C07D471/04
Filed: 1992-10-08
Granted: 2000-04-06
Abstract: Process for the preparation of benzo[b]naphthyridines of general formula: <IMAGE> in which R is a carboxyl, alkyloxycarbonyl, cyano, carbamoyl, alkylcarbamoyl, benzylcarbamoyl, hydroxyethylcarbamoyl or dialkylaminoethylcarbamoyl radical or a dialkylcarbamoyl radical in which the alkyl parts may optionally form, with the nitrogen atom to which they are attached, a 5- or 6-membered heterocycle optionally containing another heteroatom chosen from oxygen, sulphur or nitrogen and optionally substituted on the nitrogen by an alkyl radical, R' is H, alkyl, fluoroalkyl, carboxyalkyl, (3 to 6 C)cycloalkyl, fluorophenyl, difluorophenyl, alkyloxy or alkylamino, and Hal is halogen, and their salts, where such exist, characterised in that:   1) an amine of general formula: R'-NH-CH2-CH2-R'' in which R'' is alkyloxycarbonyl, cyano, carbamoyl, alkylcarbamoyl, benzylcarbamoyl, hydroxyethylcarbamoyl, dialkylaminoethylcarbamoyl or dialkylcarbamoyl in which the alkyl parts may optionally form, with the nitrogen atom to which they are attached, a 5- or 6-membered heterocycle optionally containing another hetero atom chosen from oxygen, sulphur or nitrogen and optionally substituted on the nitrogen by an alkyl radical, is condensed with a chlorofluoroquinoline of general formula: <IMAGE> in which R1 is an alkyl radical, the alkyl radicals mentioned above have 1 to 4 C and are straight or branched,   2) the fluoroquinoline of general formula: <IMAGE>  in which R1 is defined as above in 1), is cyclised, 3) the 1,2,3,4-tetrahydrobenzo[b][1,8]naphthyridine of general formula: <IMAGE> is oxidised and the ester obtained is then optionally converted to an acid and optionally converted to a salt.
Patent DE-69304037-D1 (DE)
Inventor: BALDI VALTER
IPC: B23P13/02
Filed: 1993-01-15
Granted: 1996-09-19
Abstract: The semifinished casting for an alloy road wheel (1) undergoes three successive machining operations in which material is removed by stages to produce an inner circumferential seating (7), destined to accommodate one bead (14) of a pneumatic tyre (13), a centre hole (10) coaxial both with the inner seating and with the axis of rotation (15) of the wheel, also a set of fixing holes (11) of which the axes describe a circle (12) centred on the axis of rotation, and finally, an outer circumferential seating (6) destined to accommodate the remaining bead (14) of the tyre (13), which is offset from the axis of rotation (15) in such a manner as to achieve a non-uniform distribution of mass, limited essentially to the part of the wheel (1) affording the outer circumferential seating (6), that varies progressively with the change in angular position around the axis of rotation (15) between a maximum and a minimum value. <IMAGE>