baber/WOPTO huggingface dataset:
Patent CA-2346539-A1 (CA)
Title: Compositions and methods for enhancing receptor-mediated cellular internalization
Inventor: EDWARDS DAVID A
IPC: A61L9/04
Filed: 1999-10-05
Abstract: Compositions and methods for improving cellular internalization of one or more compounds are disclosed. The compositions include a compound to be delivered and a biocompatible viscous material, such as a hydrogel, lipogel, or highly viscous sol. The compositions also include, or are administered in conjunction with, an enhancer in an amount effective to maximize expression of or binding to receptors and enhance RME of the compound into the cells. This leads to high transport rates of compounds to be delivered across cell membranes, facilitating more efficient delivery of drugs and diagnostic agents.  Compositions are applied topically orally, nasally, vaginally, rectally, and ocularly. The enhancer is administered with the composition or separately, either systemically or preferably locally. The compound to be delivered can also be the enhancer.
Patent CA-2352088-A1 (CA)
Title: High numerical aperture catadioptric lens
Inventor: WILLIAMSON DAVID M
IPC: H01L21/027
Filed: 2001-07-04
Abstract: A catadioptric projection optical system for use in photolithography used in manufacturing semiconductors having a quarter waveplate (12) following a reticle (10) and multiple aspheric surfaces and calcium fluoride lens elements. A quarter waveplate (12) following the reticle (10) eliminates asymmetry in reticle diffraction caused by polarized illumination. The use of additional aspheric surfaces reduces the number of lens elements and aids in reducing aberrations. Calcium fluoride elements are used in the lens group adjacent the wafer (50) to help minimize compaction. In one embodiment, only calcium fluoride material is used. The present invention provides a projection optics system having a numerical aperture of 0.75 for use with wavelengths in the 248, 193, and 157 nanometer range. The object and image locations are separated by a predetermined distance, making possible retrofitting of older optical systems. The present invention is particularly suited for use in semiconductor manufacturing and has improved imaging with less aberrations, particularly at shorter wavelengths.
Patent CA-2352630-A1 (CA)
Title: Gaming machine with concealed image bonus feature
Inventor: CASEY MICHAEL P
IPC: G07F17/32
Filed: 2001-07-06
Abstract: A gaming machine controlled by a processor in response to a wager, comprises a basic game and a bonus feature. The basic game includes a plurality of basic game outcomes. The plurality of basic game outcomes include a start-bonus outcome.  The bonus feature is triggered by the start-bonus outcome and indicated on a visual display. The bonus feature includes a selection stage succeeded by a bonus stage. In the selection stage, the visual display initially depicts an assemblage of selectable elements that conceal a unified image. The elements are successively selected by the player and/or processor to generate bonus-opportunity outcomes until an element is selected that produces a stop-selection outcome. The elements associated with each bonus-opportunity outcome are removed from the assemblage to reveal those portions of the unified image concealed by those elements. In response to the stop-selection outcome, the bonus feature proceeds to the bonus stage. In the bonus stage, each bonus-opportunity outcome generated in the selection stage earns the player an opportunity to win a respective bonus in the bonus stage.
Patent CA-2354255-A1 (CA)
Title: Compositions and methods for eliciting immune responses with a secretion-directed protein
Inventor: IATROU KOSTAS
IPC: C12N15/85
Filed: 2001-08-08
Abstract: The present invention relates to the use of nucleic acids which code for secretory fusion proteins to elicit immune responses. The secretory fusion protein comprises a signal sequence from a secretion competent protein, particularly a cytokine, which is linked in frame with the coding sequence of the antigen of interest which is normally intracellular. The nucleic acid encoding such a fusion protein is significantly more effective in its ability to elicit antibody production than the nucleic acid encoding the intracellular antigen.  The present invention thus provides for a method of generating antibodies as well as a method of eliciting protective immune response using such nucleic acids. Also provided are pharmaceutical compositions comprising these nucleic acids.
Patent CA-2357438-A1 (CA)
Inventor: TUREK JAMES A
IPC: H01R4/24
Filed: 2001-09-18
Abstract: A combination electrical connector and electrical switch comprises a three-sided shroud portion formed upon the electrical switch housing so as to ensure proper elec-trical connection of the electrical switch and electrical connector in a polarized manner. The electrical connector-comprises electrical contacts which include insulation dis-placement portions for electrical connection to external wiring, and blade reception portions for electrical connec-tion to blade members of the electrical switch wherein all electrical connections are solderless. The blade reception portions of the contacts comprise oppositely disposed, flex-ible members which are integrally connected together and which are able to self-generate the necessary forces to en-gage and retain the blade members of the electrical switch.
Patent CA-2358176-A1 (CA)
Title: Cleaning tool box
Inventor: PARK HYUK KOO
IPC: A47L13/51
Filed: 2001-10-01
Abstract: A cleaning tool box, the box including a body having a rear panel, left and right panels and upper and lower panels and left and right doors for opening and closing a front opening of the body, the box comprising: a partition panel positioned between the left panel and the right panel and assembled by the upper panel, the lower panel and the rear panel in order to partition an inner space of the body; a shelf positioned between the upper panel and the lower panel and secured by the left panel and the partition panel in order to partition an inner space of the body; a rag fixing rack positioned at an upper end between the right panel and the partition panel and fixed by the shelf, the right panel and the rear panel to allow free access by a rag and to stably secure a handle at the rag; a rag pad positioned between the rag fixing rack and the lower panel and fixed by the shelf and the right panel to allow a head part of the rag to be hitched thereat; and two water containers accommodated on floor of the body, such that filthy water and foreign objects flowing from rag can be instantly emptied from the water containers and drying efficiency of the rag is improved to remove generation of stench and to maintain a constant sanitary state.
Patent CA-2359181-A1 (CA)
Inventor: ALAMDARI HOUSHANG D
IPC: B22D27/20
Filed: 2001-10-15
Abstract: The invention relates to a grain refining agent for cast aluminum products containing titanium, comprising particles formed of a matrix of a ductile material, in which are uniformly dispersed boron particles having an average particle size of 0.1 to 10 µm. Where the cast aluminum products contain no titanium, the ductile material comprises titanium. The grain refining agent according to the invention does not require to be formed into a master alloy prior to being added to the molten aluminum to be cast.
Patent CA-2359727-A1 (CA)
Inventor: MURDOCH WILLIAM S JR
IPC: C07C67/03
Filed: 2000-02-04
Abstract: Disclosed herein is a process for depolymerizing and purifying contaminated post-consumer polyester. In the process, depolymerization is effected by way of glycolysis in an agitated reactor vessel. The process includes the steps of contacting a contaminated polyester with an amount of a glycol to provide a molar ratio of greater than about 1 to about 5 total glycol units to total dicarboxylic acid units at a temperature between about 150 to about 300 °C and an absolute pressure of about 0.5 to about 3 bars. This reaction is conducted for a time sufficient to produce, in the reactor, an upper layer having a relatively low density contaminant floating on top of a lower layer which includes a relatively high density depolymerized oligomer of the polyester, and separating the upper layer from the lower layer. The layers may be separated by removing the upper layer from the reactor in a first stream and removing said lower layer from the reactor in a second stream.
Patent CA-2361419-A1 (CA)
Inventor: LLOYD JOHN T
IPC: A47C3/00
Filed: 2001-11-06
Abstract: A collapsible chair for supporting a person includes a seat and a chest rest.  The chest rest may be adjusted longitudinally and rotationally when a cam lever is moved into an unlocked position. An adjustable face rest is connected to the chest rest.  The chair may also include an adjustable armrest, and detachable knee rests.
Patent CA-2362374-A1 (CA)
Title: Glitter containing filaments for use in brushes
Inventor: RUFFIN DAVID JAMES
IPC: D01F6/90
Filed: 2000-03-02
Abstract: A thermoplastic polymer monofilament oriented from 3.0-6.0 times its original length having a diameter of 125-600 microns and containing 0.2-5.0 % by weight, based on the weight of the monofilament, of glitter particles or film particles having a particle size of 50-400 microns in its longest diameter, a thickness of 2-50 microns and having a diameter to thickness ratio of at least 2 to 1 and wherein the longest diameter of the particle is not greater than 80 % of the diameter of the monofilament and that provide the monofilament with an attractive appearance. A core sheath monofilament is also part of this invention wherein the core is a thermoplastic polymer monofilament having a sheath of the same or different thermoplastic polymer containing the above described particles. These monofilaments are particularly useful in toothbrushes and cosmetic brushes.
Patent CA-2362971-A1 (CA)
Inventor: PERE EVE
IPC: C08F2/22
Filed: 2000-02-14
Abstract: The invention concerns a novel method for preparing latex by emulsion (co)polymerization of ethylenically unsaturated monomers, wherein the direct inline monitoring is carried out by Raman spectroscopy. The invention also concerns latex compositions obtainable by the emulsion (co) ploymerization method whereof the direct inline monitoring is performed by Raman spectroscopy. The invention further concerns a device for implementing said method, said device comprising a reactor, at least an optical probe, a Raman spectrometer, optical fibers, a computer and a regulating automaton.
Patent CA-2363471-A1 (CA)
Title: Snap hold frame
Inventor: SIBBETT PETER
IPC: E06B3/04
Filed: 2001-11-21
Abstract: An attachment mechanism for joining two parts together including a female member and a male member for insertion into the female member in a snap-fit relationship is disclosed. The attachment mechanism can be used to maintain two portions of a frame in removably associated.
Patent CA-2363842-A1 (CA)
Title: Chewable soft capsule having improved ingestion property and method for producing the same
Inventor: SHODAI HIDEKAZU
IPC: A23L29/00
Filed: 2000-02-23
Abstract: Soft capsules composed of the contents filled in a coating wherein the contents are in a solid or semisolid state at room temperature. These soft capsules may be chewable capsules containing a low-melting additive in the contents.      The content of the low-melting additive may be 10% or more based on the total weight of the contents and the melting point thereof may range from about 20 to 50 °C.      The low-melting additive may be selected from the group consisting of chocolate base, lard, coconut fat, macrogol (polyethylene glycol) and combinations thereof.
Patent CA-2364786-A1 (CA)
Title: A railway axle hub unit
Inventor: MORETTI ROBERTO
IPC: B61K9/12
Filed: 2000-02-29
Abstract: A railway axle hub unit of the type comprising an axle box housing (1) for supporting a bearing, is provided with a sensor body (3, 9) containing sensors (4, 5) for detecting vibration in the vertical direction and the horizontal axial direction. The sensor body is mounted onto a stationary support element (2, 1, 15) rigidly secured to the bearing, preferably an annular sealing insert. The sensors perform monitoring of the operation condition of the hub unit by generating and transmitting signals indicative of the detected level of vibration to an electronic processing unit mounted on board of the railway vehicle or the train. The processing unit is capable of signalling in real time an impending failure and/or a damaged condition associated with the monitored hub unit.
Patent CA-2365039-A1 (CA)
Title: Multilayer film and process for producing the same
Inventor: HATADA KENJI
IPC: C08J7/048
Filed: 1999-12-22
Abstract: A multilayered film which is excellent in quality and processability and can be safely and stably produced. The film is characterized in that it comprises a substrate and, formed thereon, a polymer resin layer and a vapor-deposited film of a metal and/or a metal oxide and that at least 80 wt.% of the polymer resin layer is accounted for by a polymer of an unsaturated compound having at least two ethylene bonds and/or acetylene bonds per molecule and having neither an acrylic nor methacrylic group. The film having a vapor-deposited metal coating is usable as a packaging film having gas-barrier properties, a film for capacitors, etc.
Patent CA-2366336-A1 (CA)
Title: Lampe a decharge a haute pression a reflecteur
Inventor: SCHALK SVEN
IPC: H01J5/62
Filed: 2001-01-12
Abstract: L'invention concerne un ensemble réflecteur-lampe à décharge haute pression, qui comporte: un réflecteur (2), une lampe à décharge haute pression (3), disposée dans l'axe du réflecteur (2), une première partie de culot (4), assemblée avec le col (16) du réflecteur (2), et une seconde partie de culot (5), placée devant l'ouverture de rayonnement et de sortie de lumière du réflecteur (2), se présentant sous la forme d'un embout mécanique. Selon l'invention, l'extrémité de la seconde alimentation en courant (18) de la lampe à décharge haute pression (3), conduite jusqu'à la seconde tige de lampe (10), est reliée électriquement directement à l'extrémité du second câble haute tension (7), et cette zone de connexion libre est incorporée à la seconde partie de culot (5). On obtient ainsi, dans cette connexion de lampe, une résistance aux hautes tensions et une décharge de traction élevées.
Patent CA-2367506-A1 (CA)
Inventor: IZAKI TERUAKI
IPC: C23C2/08
Filed: 2000-03-17
Abstract: A surface treated steel product which is prepared by tin-based plating or aluminum-based plating and is excellent in the resistance to corrosion, characterized as containing an intermetallic compound comprising one or more  Group IIa (alkaline earth metal) elements and one or more Group IVb elements  in a tin-based plating layer or an aluminum-based plating layer thereof. In the case of the tin-based plating layer, the intermetallic compound is preferably present in a massive form having a longer diameter of 1 .mu. or more and a ratio of a shorter diameter to a longer diameter of 0.4 or more, and in the case of the aluminum-based plating layer, the intermetallic compound is preferably present in a massive form having a longer diameter of  10 .mu. or more and a ratio of a shorter diameter to a longer diameter of 0. 4 or more.
Patent CA-2367720-A1 (CA)
Title: Cruiser awning
Inventor: TOMATSU SEIZOU
IPC: B63B17/02
Filed: 2002-01-11
Abstract: The present invention provides an awning, which is excellent in the appearance and the opening and closing operation. Roof cover 3 having a light shielding effect is provided so as to hang down forward above open cabin 2 of cruiser C, transparent window panel 4 is provided and inclined to be in parallel with said roof cover 3, said window panel 4 is made to freely open and close by sliding in the space X between the front end of the roof cover 3 and the front portion of the open cabin at the front side of the roof cover, the opening and closing operability of the window panel 4 is made excellent, and in particular, when the window panel 4 is closed, the form becomes streamline in appearance in which the wind is directed to fall forward from the window panel 4 to the roof cover 3.
Patent CA-2367827-A1 (CA)
Title: Systemes et compositions pour verres de lunettes en matiere plastique, et procedes associes
Inventor: BUAZZA OMAR M
IPC: B29D11/00
Filed: 2000-03-17
Abstract: Ce dispositif de préparation d'un verre de lunettes en matière plastique comprend une unité de revêtement et une unité de durcissement, et il est conçu, de préférence, pour permettre le fonctionnement à la fois de l'unité de revêtement et de l'unité de durcissement. En outre, il peut comprendre une unité de post-durcissement, ainsi qu'un module de commande. Ce module est conçu pour commander le fonctionnement de l'unité de revêtement, de l'unité de durcissement des verres et de l'unité de post-durcissement. L'invention concerne également une composition pour verres, pouvant contenir un monomère fonctionnel polyéthylénique de polyéther aromatique, un photoamorceur ainsi qu'un co-photoamorceur. Il est possible de durcir la composition formant le verre en appliquant une lumière activante, ou une lumière et une chaleur activantes.
Patent CA-2368185-A1 (CA)
Inventor: DENSMORE CHARLES L JR
IPC: A61K47/48
Filed: 2000-03-31
Abstract: The present invention demonstrates that polycationic, non-lipid:DNA formulations are resistant to nebulizer-induced degradation and are much mor e specific and efficient than lipid-based formulations in transfecting respiratory tract tissues in vivo. Results presented herein demonstrate that  polyethyleneimine (PEI) formulations are about 10-fold more effective than previous lipid-based formulations when delivered in vivo by jet nebulizer. Therefore, aerosolized polyethyleneimine-based formulations are provided herein for use in targeting gene therapy via the respiratory tract.
Patent CA-2368536-A1 (CA)
Inventor: OHRENBERGER GERD
IPC: F01N13/02
Filed: 2001-02-28
Abstract: A four stroke internal combustion engine having a flexible arrangement is disclosed such that the engine can be easily configured for supercharged or normally aspirated operation. The engine includes a cooling system that includes both closed loop and open loop cooling systems for improved cooling efficiency. A power take off housing located on one end of the crankcase.  Various engine components are operatively coupled to the crankshaft within the power take off housing including a cam shaft for a valve actuation assembly, a generator, an engine starting mechanism, a balance shaft, and a supercharger.  The engine contemplated in accordance with the present invention also includes a dry sump lubrication system having lubricant separator for separating lubricant from blow-by gas within the engine.
Patent CA-2370143-A1 (CA)
Title: Esters de l-carnitine ou de l-carnitines alcanoyles utilises comme lipides cationiques pour un apport intracellulaire de composes actifs d'un point de vue pharmacologique
Inventor: PISANO CLAUDIO
IPC: A61K9/127
Filed: 2000-04-11
Abstract: L'invention concerne des esters de L-carnitine et de L-carnitines alcanoyles, ces esters pouvant être utilisés comme lipides cationiques pour un apport intracellulaire de composés actifs d'un point de vue pharmacologique. Cette invention concerne également de nouveaux esters de L-carnitine et de L-carnitines alcanoyles de formule (I), dans laquelle les groupes R sont tels que définis dans la description.
Patent CA-2372654-A1 (CA)
Inventor: BOUGRI OLEG V
IPC: C12Q1/68
Filed: 2000-05-12
Abstract: Cette invention, qui a trait à de nouveaux gènes de résistance acquise dans des plantes, concerne également une méthode d'utilisation de ces gènes pour produire des plantes transgéniques résistant à la maladie.
Patent CA-2375605-A1 (CA)
Title: Peptide leukotriene receptor
Inventor: OTA TOSHIO
IPC: A61P9/08
Filed: 2000-09-13
Abstract: A cDNA encoding a novel LTC4 receptor is isolated. Provision of the LTC4 receptor which is a novel protein, enables binding experiments with the use of LTC4. By screening a compound modifying the activity of the LTC4 receptor on  the basis of these binding experiments, it becomes possible to develop drugs  targeting the LTC4 receptor.
Patent CA-2376229-A1 (CA)
Title: Procede de preparation de compositions detergentes granulaires
Inventor: BAKKER VERA JOHANNA
IPC: C11D17/06
Filed: 2000-05-26
Abstract: La présente invention porte sur un procédé de préparation d'une composition détergente granulaire présentant de bonnes propriétés à l'état de poudre. L'invention porte notamment sur un procédé dans lequel un liant liquide est mis en contact avec une substance particulaire solide dans un granulateur de fluidisation du gaz, la température du granulateur étant élevée durant le procédé.
Patent CA-2378921-A1 (CA)
Title: Lignee cellulaire comprenant le promoteur de la cyclooxygenase-2 (cox-2) et gene temoin, leur utilisation dans la recherche d'inhibiteurs selectifs de l'induction de la transcription de cox-2
Inventor: INIGUEZ PENA MIGUEL ANGEL
IPC: C12Q1/6897
Filed: 2000-07-11
Abstract: L'invention concerne une lignée cellulaire comprenant une construction d'ADN comprenant la totalité ou une partie d'une séquence promotrice du gène de la cyclooxygénase 2 (cox 2) et un gène témoin, liés opérationnellement de manière que cette séquence promotrice du gène de la cox 2 dirige l'expression de ce gène témoin en réponse à un stimulus adéquat. Ce procédé d'analyse consiste à mettre cette lignée cellulaire en contact avec le composé à analyser et à déterminer l'existence d'un signal, indiquant l'expression de l'activité, émis par le gène témoin. Ce procédé permet de rechercher des inhibiteurs sélectifs de l'induction au niveau de la transcription de la cox 2 par stimulus appropriés.
Patent CA-2383858-A1 (CA)
Title: Substituted phenyl sulfamoyl carboxamides
Inventor: TAKASUGI JAMES JAN
IPC: C07D249/08
Filed: 2001-04-30
Abstract: Novel uracil substituted phenyl sulfamoyl carboxamides (I) and salts thereof , where A = oxygen or sulfur; X1 = H, halogen, C1-C4-alkyl; X2 = H, CN, CS-NH2 , halogen, C1-C4-alkyl, C1-C4-haloalkyl; X3 = H, CN, C1-C6-alkyl, C1-C6- alkoxyalkyl, C3-C7-cycloalkyl, C3-C6-alkenyl, C3-C6-alkynyl, optionally substituted benzyl; R1, R2 = H, halogen, optionally substituted hydroxy, C1- C10-alkyl, C2-C10-alkenyl, C3-C10-alkynyl, C3-C7-cycloalkyl, phenyl, benzyl or C5-C7-cycloalkenyl, or R1 + R2 together with the atom to which they are attached form a 3- to 7-membered heterocyclic ring; Q is selected from Q1 to  Q40 as defined in the description. Use: as herbicides; for the desiccation/defoliation of plants.
Patent CA-2384070-A1 (CA)
Title: Improved aperture plate and methods for its construction and use
Inventor: BORLAND SCOTT
IPC: G03F7/40
Filed: 2000-09-08
Abstract: A method for performing an aperture plate (10) comprises providing a mandrel  (26) that is constructed of a mandrel body (28) having a conductive surface (30) and a plurality of non-conductive islands (32) disposed on the conducti ve surface. The mandrel is placed within a solution containing a material that is to be deposited onto the mandrel. Electrical current is applied to the mandr el to form an aperture plate on the mandrel, with the apertures having an exit angle that is in the range from about 30~ to about 60~.
Patent CA-2386724-A1 (CA)
Title: Ink cartridge
Inventor: SHINADA SATOSHI
IPC: B41J2/175
Filed: 2002-05-17
Abstract: In an ink cartridge (1), an opening of an ink flow groove 35 and an opening of an atmosphere communication recess 36 are formed in the front surface of a container main body (2), and sealed by a film (57), thereby constituting flow paths. (Fig. 3)