baber/WOPTO huggingface dataset:
Patent CA-2964629-A1 (CA)
Title: Ezh2 inhibitors and uses thereof
Inventor: BRADNER JAMES E
IPC: A01N43/00
Filed: 2015-11-06
Abstract: The present disclosure provides compounds of any one of Formulae (I) and (II). The compounds described herein are inhibitors of histone methyltransferases (e.g., enhancer of zeste homolog 1 (EZH1) and enhancer of zeste homolog 2 (EZH2)) and are useful in treating and/or preventing a broad range of diseases (e.g., proliferative diseases). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein. Further provided in the present disclosure are methods of identifying EZH1and/or EZH2 inhibitors.
Patent CA-2965423-A1 (CA)
Inventor: KRAGH KARSTEN MATTHIAS
IPC: C12N9/48
Filed: 2015-10-23
Abstract: A method for the production of a hydrolysate comprising: (a) admixing at least one protein or a portion thereof with: (A) at least one endoprotease; and (B) (a') at least one proline tolerant tripeptidyl peptidase or fermentate comprising a proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having: Proline at P1; and synthetic amino acids at P1; or (b') at least one proline tolerant tripeptidyl peptidase having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having: Proline at PV; and synthetic amino acids at PV; and (b) recovering the hydrolysate. The invention also relates to methods for producing a hydrolysate comprising the use of an endoprotease an exo-tripeptidyl peptidase of the S53 family and an aminopeptidase, to uses of a proline tolerant tripeptidyl peptidase, compositions, food and/or feed additive compositions comprising the same, as well as hydrolysates and uses of proline tolerant tripeptidyl peptidases.
Patent CA-2968721-A1 (CA)
Inventor: LEE DAVID SCOTT
IPC: A01H5/10
Filed: 2017-05-29
Abstract: The present invention is in the field of soybean variety CL1463739 breeding and development. The present invention particularly relates to the soybean variety CL1463739 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1463739 in a breeding program. The invention also relates to uses of soybean variety CL1463739.
Patent CA-2970972-A1 (CA)
Title: Procede et dispositif de conversion d'une version a plage dynamique elevee d'une image en une version a plage dynamique standard de ladite image
Inventor: ANDRIVON PIERRE
IPC: H04N9/64
Filed: 2015-12-09
Abstract: La présente invention concerne d'une manière générale un procédé et un dispositif de conversion d'une version à plage dynamique élevée (HDR) d'une image en une version à plage dynamique standard (SDR) de ladite image. Le procédé est caractérisé en ce qu'il convertit la version à plage dynamique élevée en la version à plage dynamique standard de l'image en fonction de : un premier indicateur (I1) qui indique la présence de paramètres de mappage des couleurs ; un deuxième indicateur (I2) qui indique si un dispositif est configuré pour convertir la version à plage dynamique élevée en la version à plage dynamique standard de l'image en tenant compte desdits paramètres de mappage des couleurs ; et un troisième indicateur (I3) qui indique si la conversion sans tenir compte desdits paramètres de mappage des couleurs est inhibée.
Patent CA-2972146-A1 (CA)
Title: Joint-sealing tape having predetermined geometry and sealing assembly having such a joint-sealing tape
Inventor: KLEIN MANFRED
IPC: E04B2/82
Filed: 2016-02-05
Abstract: The invention relates to a joint-sealing tape for sealing construction joints, in particular for sealing against sound and/or smoke and optionally against fire. In particular, the invention relates to a joint-sealing tape for sealing a joint between a first component and a second component, comprising a sealing element and an adhesive layer, said joint-sealing tape having a predetermined geometry. The invention further relates to a sealing assembly for sealing construction joints, in particular for sealing against sound and/or smoke and optionally against fire, comprising such a joint-sealing tape.
Patent CA-2973070-A1 (CA)
Inventor: SAVIAN SCOTT
IPC: A47B46/00
Filed: 2015-10-27
Abstract: An aircraft storage bin that includes an upper housing, and a bucket pivotally connected to the upper housing that cooperates with the upper housing to define a bin interior. The bucket includes a bottom, a front edge, first and second opposing side walls extending upwardly from the bottom and a center of gravity. The bucket pivots about a pivot axis with respect to the upper housing between an open position and a closed position. The center of gravity of the bucket is positioned below the pivot axis when the bucket is in the closed position.
Patent CA-2973534-A1 (CA)
Inventor: BEEKMANN ALFRED
IPC: F03D80/60
Filed: 2016-01-26
Abstract: The invention relates to a method for operating a plurality of wind energy installations (402), prepared for supplying electric power to an electrical supply system (422), that each have an aerodynamic rotor (106) with rotor blades (304) and an electrical generator (406) and also operating equipment (P). The invention proposes that the wind energy installations (402) are also operated while they are not connected to the electrical supply system (422), and in this case, at least one of the wind energy installations (402) produces electric power and inputs it into a local DC voltage system (404) that connects the wind energy installations (402) if it currently produces more power than it currently needs for supply to its own operating equipment (P), and/or its operating equipment (P) is supplied totally or in part with power from the local DC voltage system (404) if it currently produces less power than it currently needs for supply to its own operating equipment (P).
Patent CA-2973773-A1 (CA)
Inventor: MELLSTEDT HAKAN
IPC: C07D471/04
Filed: 2016-02-01
Abstract: Compounds of formula (I') or (I"): (see formula I')(see formula I") are disclosed, as well as pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising same. The disclosed compounds are useful in the treatment of malignant hyperproliferative disorders, obesity-associated metabolic complications, autoimmune disorders and inflammatory disorders.
Patent CA-2976755-A1 (CA)
Inventor: LIN RONG
IPC: A61K31/4045
Filed: 2016-02-17
Abstract: Treatment of multiple myeloma with a combination of panobinostat and bortezomib at specified doses adjusted for safety.
Patent CA-2977060-A1 (CA)
Title: Systemes de seringue, systemes de joint d'etancheite de piston, systemes de butee et procedes d'utilisation et d'assemblage
Inventor: CUPICHA MICHAEL
IPC: A61M5/178
Filed: 2016-02-19
Abstract: La présente invention concerne un système de seringue, des systèmes de joint d'étanchéité de piston, des systèmes de butée, et des procédés d'assemblage et d'utilisation des systèmes de seringue. Le système de joint d'étanchéité de piston comprend un élément joint d'étanchéité de piston et un élément tête de piston. Le système d'injection comprend un conteneur, un système de joint d'étanchéité de piston positionné à l'intérieur du conteneur, et un système de butée couplé à une extrémité du conteneur. L'invention concerne également un procédé d'assemblage d'un système d'injection, le procédé consistant à obtenir un conteneur, un système de joint d'étanchéité de piston, et un système de butée. Le procédé consiste également à insérer le système de joint d'étanchéité de piston dans une cavité à l'intérieur du conteneur. Le procédé consiste en outre à fixer le système de butée au niveau d'une extrémité du conteneur dans une ouverture de la cavité. Des procédés d'utilisation du système de seringue, des systèmes de joint d'étanchéité de piston et des systèmes de butée sont également décrits.
Patent CA-2977625-A1 (CA)
Inventor: VANDERPLOEG ERIC J
IPC: A61K9/14
Filed: 2015-12-29
Abstract: Systems and methods for preparing synthetic osteoinductive bone grafts are provided in which a porous ceramic granule, which may be incorporated within a biocompatible matrix material, is loaded with an osteoinductive agent. Loading of granules is facilitated in some cases by the use of low-pH buffers and pre-treatments.
Patent CA-2977878-A1 (CA)
Inventor: HOUSTON THOMAS SANDY
IPC: B21D53/00
Filed: 2011-10-21
Abstract: A structural component is provided comprising a base member comprising at least two sidewalls and a space therebetween, the base member having a predetermined curvilinear configuration formed using hot stretch forming. The structural component comprises at least one reinforcing member linear friction welded to the at least two sidewalls so that the reinforcing member is positioned at least partially within the space between the at least two sidewalls.
Patent CA-2978145-A1 (CA)
Title: Wastewater analyser assembly
Inventor: PERKINS KEITH
IPC: G01N33/18
Filed: 2016-03-04
Abstract: A wastewater analyser assembly comprises an overflow reservoir for receiving wastewater from an input. The overflow reservoir comprises a weir for wastewater to overflow and exit the overflow reservoir. There is a wastewater sample outlet in the overflow reservoir for passing wastewater from within the overflow reservoir to an analyser.
Patent CA-2980822-A1 (CA)
Title: Acrylic hair fixative copolymers and compositions
Inventor: LEBLANC JEAN-PIERRE
IPC: C08F220/56
Filed: 2016-04-20
Abstract: A hair fixative composition comprising a film forming polymer that is prepared from monomers comprising (a) 10- 30% by weight of one or more copolymerizable comonomers selected from the group consisting of N-alkyl (meth)acrylamide wherein the alkyl group thereof contains from 2 to 12 carbon atoms, wherein for at least one of said copolymerizable comonomers the alkyl group contains from 5 to 12 carbon atoms; (b) 14-21 % by weight of copolymerizable comonomers comprising acrylic acid and optionally one or more acidic copolymerizable comonomers selected from the group consisting of methacrylic acid, crotonic acid, itaconic acid, maleic acid, fumaric acid, and the (C1 -C4)alkyl half esters of maleic and fumaric acids; and (c) 40-76% by weight two or more copolymerizable comonomers selected from the group consisting of (C1-C12)alkyl(meth)acrylates, wherein at least one of said two or more copolymerizable comonomers is a (C1-C2)alkyl(meth)acrylate; said film forming polymer being optionally completely or partially neutralized with a basic reagent.
Patent CA-2982007-A1 (CA)
Title: Registry domain name management
Inventor: SLAUNWHITE DONALD
IPC: H04L12/16
Filed: 2017-10-11
Abstract: Methods and systems for managing domain names are disclosed. A server hosts a platform that interfaces with users. The server is operably coupled to the registry and domain management database, and receives transaction requests to assign tags to one or more domain names, the tags used as identifiers to associate information with the domain names. The server stores the domain names with one or more tags and associated information in the domain management database. The server receives a request to perform a registry event on a domain name and checks if there are tags associated with the domain name of which the event was requested.  If there is no assigned tag the server performs the registry event action. If there is an associated tag the server complies with the tag and associated tag information.
Patent CA-2982580-A1 (CA)
Inventor: LI ZHANMING
IPC: H01L29/41
Filed: 2017-10-16
Abstract: This invention relates to interdigitated electrodes for power electronic and optoelectronic devices where field and current distribution determine the device performance.  Described are geometries based on rounded asymmetrical fingers and electrode bases of varying width. Simulations demonstrate benefits for reducing self-heating and thermal power loss, which reduces overall on-state resistance and increases reverse break down voltages.
Patent CA-2982861-A1 (CA)
Inventor: ALLISON DANIEL S
IPC: A61K45/06
Filed: 2016-04-15
Abstract: The present invention is directed to antagonistic antibodies and antigen binding fragments thereof having binding specificity for PACAP. These antibodies inhibit, block or neutralize at least one biological effect associated with PACAP, e.g., vasodilation. In exemplary embodiments these antibodies and antigen binding fragments thereof may comprise specific VH, VL, and CDR polypeptides described herein. In some embodiments these antibodies and antigen binding fragments thereof bind to and/or compete for binding to specific epitope(s) on human PACAP. The invention is further directed to using these antagonistic anti-PACAP antibodies, and binding fragments thereof, for the diagnosis, assessment, and treatment of diseases and disorders associated with PACAP and conditions where antagonism of PACAP-related activities, such as vasodilation, mast cell degranulation, and/or neuronal activation, are therapeutically beneficial, e.g., headache and migraine indications.
Patent CA-2982921-A1 (CA)
Inventor: HULTEEN JOHN C
IPC: A62C2/06
Filed: 2016-03-30
Abstract: Described herein is a firestop for construction assemblies comprising a penetration wherein a packing material and a non-porous adhesive article are used to fill and seal the opening.
Patent CA-2984108-A1 (CA)
Inventor: DUSSAULT DONALD HERBERT
IPC: A61H31/00
Filed: 2016-05-23
Abstract: Disclosed is apparatus (1.50) for assisting a user during a cardiopulmonary resuscitation of a patient (40), said apparatus comprising: a force-transmission unit (10) having a lower plate (11) that can be placed on the chest of the patient (40), an upper plate (12) located at a distance from the lower plate (11) and a force sensor (13) arranged between the lower plate (11) and the upper plate (12) for detecting a force that can be exerted on the chest of the patient (40) by means of the upper plate (12) and the lower plate (11); a display device for generating at least one signal that can be perceived by the user; and an electronic control device for controlling the display device on the basis of the force detected by the force sensor, wherein the force-transmission unit (10) is embedded in a flexible mat (2).
Patent CA-2985154-A1 (CA)
Inventor: GROTHE SONJA
IPC: B01J21/06
Filed: 2016-05-13
Abstract: The invention relates to a powdered titanium oxide that has been inorganically treated with silicon, to a method for the production thereof, and to the use thereof in the production of catalysts, in particular for use as photocatalysts and as carriers for refinery catalysts. The catalyst material has an isoelectric point at pH 4.0 to 7Ø
Patent CA-2989332-A1 (CA)
Inventor: MOORE MARTIN L
IPC: A61K39/12
Filed: 2016-06-15
Abstract: This disclosure relates to multivalent enterovirus vaccine compositions and uses related thereto. In certain embodiments, the disclosure relates to vaccine compositions comprising multivalent, mixtures of enterovirus (for example HRV) serotypes or recombinantly produced variants or recombinantly produced viral capsid proteins. In certain embodiments, the disclosure relates to methods of immunization comprising administering an effective amount of compositions disclosed herein to a subject diagnosed with, exhibiting symptoms of, or at risk of an enterovirus infection.
Patent CA-2991040-A1 (CA)
Inventor: BORRELLO IVAN M
IPC: C07K19/00
Filed: 2016-06-29
Abstract: Dans certains aspects, les modes de réalisation de l'invention concernent des compositions et des procédés associés à des protéines transmembranaires chimériques. Les protéines chimériques transmembranaires peuvent comprendre le domaine extracellulaire d'un récepteur inhibiteur, et un domaine de signalisation intracellulaire qui peut activer une réponse immunitaire.
Patent CA-2995804-A1 (CA)
Inventor: BELL KEVIN
IPC: G03B15/06
Filed: 2018-02-21
Abstract: Systems and methods for simultaneous image acquisition are provided herein. An apparatus for simultaneous image capture may include a camera, and a chamber with an aperture, the camera oriented to capture light emitted through the aperture. The chamber may include at least first and second mirrors positioned inside the chamber with a defined angle between them, and a holder for an object to be imaged, the holder positioned inside the chamber between the first and second mirrors. In embodiments, the field of view of the camera includes at least portions of the first and second mirrors with respective portions of the object reflected by the first and second mirrors. Other embodiments may be described and/or claimed.
Patent CA-2996384-A1 (CA)
Inventor: LIMODEHI HAMID E
IPC: G01N21/77
Filed: 2018-02-23
Abstract: A humidity sensing method and system comprising a transmitter, comprising a fiber optic head and a light source comprising a single LED emitting a measuring light, a receiver, and a sensing assembly comprising a plurality of optical fibers each comprising a first end fed the measuring light, a transducer positioned along a length thereof, the transducer comprising a side-polished portion of the optical fiber, the side polished portion coated with a gold layer and a film of a hydrophilic material wherein the transducer modifies an intensity of the measuring light dependent on an ambient humidity, and a second end for feeding the modified measuring light to the receiver, wherein the receiver compares an intensity of the measuring light with an intensity of the modified measuring light deriving therefrom a corresponding humidity level and dew point temperature.
Patent CA-2996536-A1 (CA)
Title: Systems, methods and apparatus for presenting relevant programming information
Inventor: CARLSON JAY P
IPC: H04N21/482
Filed: 2016-08-26
Abstract: Various embodiments of systems, apparatus, and/or methods are described for presenting relevant programming information. A viewing action of an audiovisual event is detected on a receiving device. Data associated with the viewed audiovisual event is then retrieved. The retrieved data includes at least receiving device information and audiovisual event information. The retrieved data is then stored in a historical viewing database, and at least one scoring table is generated from the data in the historical viewing database. Programming information for a plurality of candidate audiovisual events that are available to be viewed is then organized based at least in part on the at least one scoring table and a selected time, and the organized programming information is output to a presentation device.
Patent CA-2999600-A1 (CA)
Inventor: FISCHER FRIEDRICH
IPC: A01J7/02
Filed: 2016-09-06
Abstract: The invention relates to milking equipment (10) comprising at least one, in particular four teat cups (12), wherein each teat cup (12) has a cup housing (14) and a teat cup liner (16), accommodated in the cup housing (14), having a head region (18) and a suction region (20). At the cup bottom (22) or at the end of the suction region (20) of the teat cup liner (16) there is a connection (26) for a milk tube (24). It is proposed that a mouth portion (32) of a sterile-air pressure line (34) be arranged in the head region (18) of the teat cup liner (16), sterile air with a volumetric flow rate (Vs) greater than a fluid extraction volumetric flow rate (Vm) at the milk tube (24) being passable through said sterile-air pressure line (34), such that a sterile-air overlay (84) is established in the head region (18) of the teat cup liner (16). In secondary aspects, the invention relates to a milking installation (60), to a teat cup liner (16) for the milking equipment (10) and to a milking method with sterile-air overlay. The invention prevents milked milk from being contaminated by contaminants and germs in the stable air, and so increased durability of untreated raw milk can be achieved.
Patent CA-3000646-A1 (CA)
Inventor: LEI JING
IPC: H04L5/00
Filed: 2016-08-25
Abstract: Aspects of the present disclosure provide techniques for design of synchronization signals for narrowband operation and other clean-slate, OFDM based systems such as enhanced component carrier (eCC) systems. An example method is provided for operations which may be performed by a BS to generate and transmit a dual-layer PSS, and correspondingly, techniques for a UE to detect the dual-layer PSS. The PSS may be generated utilizing a binary code cover and at least one sequence applied to a number of symbols within one or more subframes of a frame.
Patent CA-3002375-A1 (CA)
Title: Raccords de tuyauterie et douilles de raccord
Inventor: LAWRENCE BENJAMIN L
IPC: F16L21/03
Filed: 2018-04-23
Abstract: Une douille de raccord pour une connexion tubulaire comprend un boîtier de douille ayant une composition dalliage métallique et une partie détanchéité. Un joint détanchéité primaire est positionné à lintérieur de la partie détanchéité. Le joint détanchéité primaire comprend un matériau élastomère ayant une température de service. Une ou plusieurs bagues despacement sont positionnées à lintérieur de la partie détanchéité. Un joint détanchéité secondaire est positionné à lintérieur de la partie détanchéité. Le joint détanchéité secondaire comprend une composition métallique, dans laquelle le joint détanchéité secondaire a une température de fusion supérieure ou égale à la température de service du joint détanchéité primaire. Une ou plusieurs bagues de verrouillage sont positionnées à lintérieur de la partie détanchéité, chacune des une ou plusieurs bagues de verrouillage comprenant un élément de morsure défini le long dune circonférence interne de la bague de verrouillage.
Patent CA-3005211-A1 (CA)
Inventor: BALASUBRAMANIAN RAMAKRISHNAN
IPC: A61L2/16
Filed: 2016-11-11
Abstract: Methods of employing corrosion inhibitors with oxidizing and/or non-oxidizing biocides, such as peroxycarboxylic acids, to provide corrosion protected compositions are disclosed. Various corrosion inhibitors further provide biocidal efficacy in addition to the corrosion protection providing further benefits for application of use. Methods of employing corrosion protected biocide compositions, such as peroxycarboxylic acid compositions, for corrosion protection are particularly well suited for treating fluids intended to flow through pipes, namely in the energy industry, water and paper industries, etc. Methods providing suitable corrosion protection in comparison to untreated systems and corrosion protected systems using conventional corrosion inhibitors, such as quaternary amines and imidazolines commonly used in the industry, are disclosed.
Patent CA-3005251-A1 (CA)
Title: Lipides en tant que vecteurs synthetiques pour ameliorer le traitement et la presentation de l'antigene ex-vivo en therapie cellulaire dendritique
Inventor: CONN GREG
IPC: C07K17/04
Filed: 2016-11-14
Abstract: L'invention couvre l'utilisation de certaines catégories de lipides comprenant des lipides cationiques dans des thérapies cellulaires dendritiquesex-vivo. Les lipides cationiques améliorent l'absorption des antigènes, le traitement et la présentation des antigènes traités par des cellules dendritiques aux lymphocytes T CD8 + et CD4 + via les voies de présentation des classes I et II du CMH respectivement. L'absorption des antigènes via un lipide cationique par des cellules dendritiques entraîne une baisse sensible de la population des lymphocytes T régulateurs immunosuppresseurs dans les tumeurs et une augmentation significative de la tumeur ciblant des lymphocytes T cytotoxiques. La perte en lymphocytes T régulateurs et l'augmentation de cellules cytotoxiques spécifiques de tumeurs sont propices à une élimination efficace des tumeurs.
Patent CA-3006513-A1 (CA)
Inventor: DROCHE EMILE
IPC: A61F13/02
Filed: 2016-12-09
Abstract: Dressing for skin care, having a main compress covered by a membrane (2) with an adhesive contour (12) which extends beyond this compress and which is designed to be applied to the skin, this dressing having an inlet opening (6) for a treatment liquid (22) on the main compress, and the membrane having, on at least part of the surface opposite this compress, a permeability that permits exchange of gases.