baber/WOPTO huggingface dataset:
Patent DK-0440777-T3 (DK)
Inventor: HYMAN CAROLYN
IPC: A61K38/00
Filed: 1990-08-29
Granted: 1997-04-21
Abstract: The present invention relates to nucleic acid sequences encoding brain derived neurotrophic factor (BDNF), as well as BDNF protein produced in quantity using these nucleic acid sequences, as well as fragments and derivatives thereof. In addition, the invention relates to pharmacologic compositions and therapeutic uses of BDNF, having provided, for the first time, the means to generate sufficient quantities of substantially pure BDNF for clinical use. In a specific embodiment, BDNF may be used to promote the survival of substantia nigra dopaminergic neurons and basal forebrain cholinergic neurons, thereby providing a method for treating, respectively, Parkinson's disease and Alzheimer's disease. The invention also relates to antibodies directed toward BDNF or fragments thereof, having provided a method for generating sufficient immunogen. Further, by permitting a comparison of the nucleic acid sequences of BDNF and NGF, the present invention provides for the identification of homologous regions of nucleic acid sequence between BDNF and NGF, thereby defining a BDNF/NGF gene family; the invention provides a method for identifying and isolating additional members of this gene family.
Patent DK-0451801-T3 (DK)
Inventor: HOLMES WILLIAM SAMUEL
IPC: C01B25/10
Filed: 1991-04-10
Granted: 1994-04-05
Abstract: Chlorophosphorus compounds are produced in a loop apparatus wherein chlorine is added to a recycling medium comprising chlorophosphorus compound and elemental phosphorus.
Patent DK-0481756-T3 (DK)
Inventor: FUJIWARA HIROMICHI
IPC: A61K31/40
Filed: 1991-10-16
Granted: 1998-02-16
Abstract: A benzamide derivative represented by the formula: <CHEM> having a promoting activity of gastrointestinal tract and pharmacentical composition containing the same.
Patent DK-0451108-T3 (DK)
Inventor: MAGNOLLAY GILBERT
IPC: B29C48/30
Filed: 1991-03-28
Granted: 1995-04-03
Abstract: The extrusion head (2) is firmly attached to the adaptor element (11) which comprises coupling bushes (20) driven into the bores (19). The adaptor element (13) is equipped with bushes (21) and is firmly attached to the adaptor unit (9). The clamping jaws (30 and 26) are connected to the knuckle-joint articulated system (25, 24, 27, 28), which is actuated by a ram, such that the clamping jaws (26 and 30) move away from one another in order to release the adaptor elements and, in the other position, press the adaptor elements against one another by acting on the bevelled edges (16). 
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Patent DK-0594576-T3 (DK)
Inventor: HURSTING MARCIE J
IPC: C12P21/08
Filed: 1990-11-02
Granted: 2000-02-07
Abstract: Monoclonal antibodies and fragments thereof, with binding specificity for an epitope on the carboxy terminus of prothrombin activation peptide F1.2, which can be used in immunoassays to predict thrombosis by measuring the extent of activation of prothrombin. These monoclonal antibodies are also included in a kit for performing such immunoassays.
Patent DK-0535118-T3 (DK)
Inventor: KAVANAGH DEAN LYLE
IPC: C03C27/12
Filed: 1991-05-23
Granted: 1995-09-11
Abstract: A flexible, draw-formed laminate for a safety glazing comprising a transparent, thermoplastic carrier film which is shrink-stable during laminating formation of such safety glazing bonded to at least one layer of plasticized polyvinyl butyral, such film having a greater tensile modulus than that of the layer of plasticized polyvinyl butyral. The carrier film is preferably flexible polyester such as polyethylene terephthalate having one or more functional performance coatings or layers on its surface such as a multi-layered solar radiation control stack.
Patent DK-0501784-T3 (DK)
Inventor: MAHER ROBERT J
IPC: G06V10/70
Filed: 1992-02-26
Granted: 1999-06-23
Abstract: The acceptability of the appearance of objects (12) such as consumer products is determined by forming an initial discriminant function (F) as a composite of a relatively small number of images (I) which are known to be acceptable. This initial discriminant function is then used to gather statistical information (P, A, B, C) about how a first relatively large number of images compare to the initial discriminant function. Thereafter, this statistical information is used (318-324) to select or aid in the selection of acceptable images from a second relatively large number of images, and the images selected as acceptable are used (334) to refine the discriminant function. The refined discriminant function is then used (e.g., during actual product inspection (402-414)) to determine which objects have an acceptable appearance and which do not. <IMAGE>
Patent DK-0539204-T3 (DK)
Inventor: VON ITZSTEIN
IPC: A61K31/351
Filed: 1992-10-22
Granted: 1998-09-07
Abstract: N-Acetylneuraminic and derivatives of formula (I) <CHEM> (wherein R, R<1>, R<2>, R<3> and R4 are defined in the specification) pharmaceutical formulations thereof, their use in medicine, in particular as antiviral agents and methods for their preparation are described.
Patent DK-0538139-T3 (DK)
Inventor: ARSAC JEAN-FRANCOIS
IPC: C08L25/06
Filed: 1992-10-16
Granted: 1996-11-25
Abstract: Heat-sealable and peelable film for polystyrene containers, consisting of at least one film comprising a mixture (a) of polystyrene, (b) of one or more copolymer(s) of ethylene and of acrylic derivatives. Also a process for sealing a polystyrene container by means of the said film and the heat-sealed polystyrene container thus obtained.
Patent DK-0583339-T3 (DK)
Inventor: VON DER OSTEN CLAUS
IPC: C12R1/19
Filed: 1992-04-30
Granted: 1999-04-19
Abstract: PCT No. PCT/DK92/00138 Sec. 371 Date Nov. 11, 1993 Sec. 102(e) Date Nov. 11, 1993 PCT Filed Apr. 30, 1992 PCT Pub. No. WO92/19729 PCT Pub. Date Nov. 12, 1992The invention relates to stabilized subtilisin proteases wherein one or more prolines is substituted for a native amino acid at stabilizing positions defined both by the range of the dihedral angles in the primary structure present at the substitution site and by selected characteristics of the protease secondary structure in the vicinity of the substitution site, to nucleotide sequences that encode the stabilized proteases, and to host organisms that contain the nucleotide sequences encoding the stabilized proteases.
Patent DK-0592566-T3 (DK)
Inventor: SKELLY SUSAN M
IPC: C12R1/19
Filed: 1992-07-02
Granted: 1999-12-13
Abstract: Muteins of IL-6 and truncated IL-6 are prepared by recombinant DNA techniques. In the muteins, the cysteine residues that occur at positions, or at positions corresponding to positions, 45 and 51 of mature, native IL-6 have been replaced by other amino acids. The cysteine residues that occur at positions, or at positions corresponding to positions, 74 and 84 are retained. The molecule has biological activity that is at least comparable to that of native IL-6.
Patent DK-0609340-T3 (DK)
Inventor: BLANEY TED LEE
IPC: A61F13/49
Filed: 1992-10-20
Granted: 1997-03-17
Abstract: Disposable absorbent articles such as baby diapers or adult incontinent briefs provided with a refastenable adhesive fastening system. The adhesive fastening system preferably comprises a pair of tape tabs each having an adhesive surface which during use is adhered to a landing member having an adherence surface which may comprise only the backsheet that has no reinforcement for strength against tearing or may comprise a reinforced backsheet. The invention improves bond security while at the same time making the fastening system more easy to remove without tearing by careful optimization of the properties of the adhesive, the tape tab, and the landing member. In particular, it has been found that the adhesive fastening system should have a Standard Shear Hang Time of greater than about 1000 minutes per square inch. The surface characteristics, toughness, and elasticity modulus of the landing member is optimized while the adhesive aggressiveness (quick-stick) of the adhesive is optimized with preferred low coating weights of the adhesive and low calculated caliper for the landing member so as to provide an adhesive fastening system that bonds easily, holds securely and is refastenable.
Patent DK-0595467-T3 (DK)
Inventor: BARNETT CHARLES JACKSON
IPC: A61P35/00
Filed: 1993-09-24
Granted: 2000-09-18
Abstract: A process for preparing a 4-hydroxypyrrolo[2,3-d]pyrimidine without isolation or purification of intermediate products, of formula <CHEM>  wherein     R is NHC*H(COOR<1>)CH2CH2COOR<1> or OR<1>;     R<1> is H or a carboxyl protecting group;     the configuration about the carbon atom designated * is L;     n is 0 or 1; and     A is an aryl group which may be substituted;  or a salt thereof, which comprises     (a) halogenating a compound of the formula <CHEM>  wherein     R, R<1>, A and * are as defined above;     j is 0 or 1; (b) reacting 2,4-diamino-6-hydroxypyrimidine, or a salt thereof, with the reaction product from step (a), in the presence of a polar solvent; (c) optionally hydrolyzing the reaction product of step (b) when R of said reaction product is NHC*H(COOR<1>)CH2CH2COOR<1> and R<1> is a carboxyl protecting group; and (d) optionally salifying the reaction product of step (b), when R of said reaction product is NHC*H(COOR<1>)CH2CH2COOR<1> and R<1> is H, or of step (c).
Patent DK-0659049-T3 (DK)
Inventor: OLESEN TINE
IPC: A21D8/04
Filed: 1993-08-23
Granted: 2001-07-23
Abstract: A method of improving properties of a dough and/or a baked product made from dough by adding an enzyme preparation to the dough and/or to any ingredient and/or to any mixture of the dough ingredients, in which the enzyme preparation comprises a lipase derived from Humicola, and a second enzyme which is an amylase or a xylanase.
Patent DK-0658159-T3 (DK)
Inventor: BUZZETTI FRANCO
IPC: C07D401/06
Filed: 1994-05-26
Granted: 2000-12-18
Abstract: Oxindole, acrylamide, thioacrylamide and acrylonitrile compounds, and their pharmaceutically acceptable salts, which are useful as tyrosine kinase inhibitors.
Patent DK-0711546-T3 (DK)
Inventor: VALLET MAS JOSE ALBERTO
IPC: A61K9/00
Filed: 1994-09-07
Granted: 2001-04-23
Abstract: The ophtalmic solution comprises (a) the equivalent to 0.001-0,14 % of Diclofenac itself or an isomer, or a derivative or one of the pharmaceuticaly acceptable salts thereof; (b) the equivalent to a value of 0.001-0.45 % of Tobramicine, obtained from Tobramicine itself or from an isomer or a derivative or one of its pharmaceutically acceptable salts thereof; (c) optionally a solubilizer, an isotonizer, a pH damper, a viscosizer, a chelator, a preserving agent, and/or an excipient for pharmaceutical hydrogels. Application to the treatment of ocular and otic inflammations and/or infections.
Patent DK-0809468-T3 (DK)
Inventor: JOHNSON CHRIS E
IPC: A61F2/46
Filed: 1996-02-15
Granted: 2004-03-29
Abstract: A cutting guide for resecting a patient's proximal tibia to receive a tibial prosthesis is disclosed. The cutting guide comprises an instrument body (76) and mounting means for attaching the cutting guide to a rod (21) that tracks the patient's intramedullary canal (12) which enables the surgeon to reference surgical cuts with respect to the patient's intramedullary canal. The cutting guide also comprises a cutting element (78) for being driven longitudinally into the proximal tibia during use, and at least one cutting guide surface (90, 91) for guiding a saw instrument of the surgeon.
Patent DK-0819117-T3 (DK)
Inventor: PEREGO BRUNO
IPC: C07D211/90
Filed: 1996-03-14
Granted: 1999-11-08
Abstract: PCT No. PCT/EP96/01090 Sec. 371 Date Aug. 18, 1997 Sec. 102(e) Date Aug. 18, 1997 PCT Filed Mar. 14, 1996 PCT Pub. No. WO96/29310 PCT Pub. Date Sep. 26, 1996A method for the preparation of 4-(nitrophenyl)-dihydro-pyridines by reacting a benzaldehyde with an acetoacetate and reacting the resulting benzylidene derivative with an enamine derivative. Both reactions are catalyzed by dimethylamine benzoate or p-anisate.
Patent DK-0815065-T3 (DK)
Inventor: BLOCKEN WILFRIED
IPC: C04B18/20
Filed: 1996-03-14
Granted: 1999-08-23
Abstract: PCT No. PCT/EP96/01084 Sec. 371 Date Sep. 19, 1997 Sec. 102(e) Date Sep. 19, 1997 PCT Filed Mar. 14, 1996 PCT Pub. No. WO96/30315 PCT Pub. Date Oct. 3, 1996The invention concerns insulating mortar which displays very good heat-insulating properties. It contains at least 70 vol. %, preferably at least 80 vol. %, in particular at least 85 vol. %, recycled, comminuted hard polyurethane, the remainder consisting of cement and optionally additives as well as water for setting purposes.
Patent DK-0930883-T3 (DK)
Inventor: TEHIM ASHOK
IPC: C07D471/06
Filed: 1997-10-20
Granted: 2006-05-22
Abstract: A pharmaceutical composition comprising a compound of Formula I wherein R1 is selected from, inter alia, alkyl, aryl-loweralkyl, heterocycle-loweralkyl, loweralkyl-carbonate; optionally substituted amino; benimidaz-2-yl; optionally substituted phenyl; loweralkyl-(R5)(R6) wherein one of R5 and R6 is selected from H and the other is selected from carboxy, carboxy-loweralkyl and loweralkoxycarbonyl; NHCH2CH2OX wherein X represents an in vivo hydrolyzable ester; and R2 and R3 are independently selected from H, NO2, halo, di(loweralkyl)amino, cyano, C(O)OH, phenyl-S-, loweralkyl, and Z(O)OR7 wherein Z is selected from C and S and R7 is selected from H, loweralkylamino and arylamino; or pharmaceutically acceptable salts or certain in vivo hydrolyzable esters or amides thereof, in an amount effective to inhibit neurotrophin-mediated activity, and a suitable carrier, is described. The compositions are useful to inhibit undesirable neurotrophin-mediated activity such as the neurite outgrowth that occurs in some neurodegenerative disease states.
Patent DK-0880868-T3 (DK)
Inventor: KURTZ SCOTT DAVID
IPC: G10L19/04
Filed: 1997-11-04
Granted: 2005-03-14
Abstract: A wireless communication unit comprising means for transmitting data to a second communication unit using at least one of a plurality of data rates, at least one of a plurality of time slots, at least one of a plurality of modulation schemes, and at least one of a plurality of coding rates in a plurality of time division multiple access (TDMA) frames.
Patent DK-0878318-T3 (DK)
Inventor: AUF DER HEIDE CHRISTIAN
IPC: B41M1/40
Filed: 1998-05-06
Granted: 2002-03-11
Abstract: The tube is first printed and is then heat-shrunk into a circular shape and filled. The tube is first flat-printed symmetrically with the tube centre-line before the tube is bent into a ring. The initial printed image applied is distorted in comparison with the unfolded image. The distortion of the printed image is equal to the change in shape of the tube as a consequence of subsequent tube-shrink. A pre-print distortion factor is calculated which is related to the ring geometry and the heat-shrink characteristics of the plastics tube. The distortion factor relates to the centreline of the product in the filled ring and is positive, and is added to the longitudinal dimension of the printed image.
Patent DK-0856537-T3 (DK)
Inventor: VAN ERDEN DONALD
IPC: C08J11/00
Filed: 1998-01-28
Granted: 2003-10-06
Abstract: The present invention is a process of making strap using both post consumer and non-post consumer PET of wide distribution intrinsic viscosity (IV) through direct solid state polymerization in a non-peletized state to produce PET with an increased, heterogenous IV suitable for high performance strap extrusion. The process increases the IV of post-consumer resins, consisting principally of polyethylene terephthalate (PET), by preferably chopping the post-consumer plastic into flakes and chunks, rolling the flakes and chunks, preheating the flakes, and further heating the pre-heated flakes and chunks in an atmosphere of hot nitrogen gas, thereby increasing their intrinsic viscosity. PET polymers having increased viscosities provide a polymer useful in manufacturing a high performance strap material.
Patent DK-0879611-T3 (DK)
Inventor: SUDO MASAMICHI
IPC: A61M5/24
Filed: 1998-05-19
Granted: 2001-07-16
Abstract: There can be provided a sealing stopper for a syringe, having very high sealing property and sliding property, and a prefilled syringe using this sealing stopper and capable of preserving a medicament for a long time and operating in easy and precise manner during injecting. This syringe is also excellent in sanitary and operating property during a step of formulation or preservation of a medicament. In this sealing stopper for a syringe, a surface of the rubber body is laminated with a tetrafluoroethylene resin film or ultrahigh molecular weight polyethylene film having an average roughness Ra on the central line of the surface in a range of at most 0.05  mu m and a kinematic friction coefficient of at most 0.2. <IMAGE>
Patent DK-1032474-T3 (DK)
Inventor: LOEFFLER HELMUT
IPC: B05D5/00
Filed: 1998-11-05
Granted: 2001-11-19
Abstract: Process for producing a multi-layer lacquer finish, in which a surfacer coating compound is applied to a substrate optionally pre-coated with a priming layer and/or further coating layers, and a top coating comprising a color-imparting and/or special-effect-imparting base lacquer layer and a transparent clear lacquer layer, or a top coating comprising a pigmented one-layer top lacquer, is then applied, in which the surfacer coating compound which is used is one which either contains binders which are curable exclusively by free radical and/or cationic polymerization, wherein the said binders are cured by means of high-energy radiation, or is one which contains binders which are curable by free radical and/or cationic polymerization, wherein the said binders are cured by means of high-energy radiation, and additionally contains chemically cross-linking binders.
Patent DK-1090143-T3 (DK)
Inventor: FERGUSON MARK WILLIAM JAMES
IPC: C12N15/09
Filed: 1999-06-25
Granted: 2005-08-15
Abstract: The present invention relates to a method for quantifying the amount of active transforming growth factor beta (TGF- beta ) in biological samples. In particular the method comprising incubating cryosections of a tissue with cells which contain a TGF- beta  responsive expression vector having a structural region encoding an indicator protein and measuring the amount of said indicator protein expressed from the cells.
Patent DK-1108193-T3 (DK)
Inventor: FIEBACK KLAUS
IPC: B65D81/18
Filed: 1999-07-06
Granted: 2002-07-01
Abstract: The present invention relates to a latent heat body (1, 17, 20, 30, 39, 49, 50) with a paraffin-base latent heat storage material (7, 7',7'', 54, 55) lodged in a support material (5) having locating chambers. The invention aims at improving said latent heat body in such a way that it exhibits high heat storage capabilities while being easy to produce, that it exhibits sufficient structural resistance even when it is in a heated state and that the support material is automatically filled with latent heat storage material to the greatest possible extent. To this end, capillary locating chambers (6) for the latent heat storage material (7, 7',7'', 54, 55) are configured inside the support material (5) and the support material (5) contains a mineral matter with open capillary pore structure (8). The invention also relates to a method for the production of a latent heat body (1, 17, 20, 30, 39, 49, 50) with a paraffin-base latent heat storage material (7, 7',7'', 54, 55) lodged in a support material (5) having locating chambers. In order to enable easy and cost-effective production, the invention provides that the latent heat storage material (7, 7', 7'', 54, 55) be liquefied, that the previously liquefied latent heat storage material (7, 7', 7'', 54, 55) be fed to the self-suctioning capillary locating chambers (6) of the support material (5) and that a support material (5) be used which contains a mineral matter with open capillary pore structure (8).
Patent ES-2250035-T3 (ES)
Title: Catalizador para la purificacion de los gases de escape de motores diesel y proceso para su preparacion.
Inventor: DOMESLE DR RAINER
IPC: F01N3/10
Filed: 2000-03-01
Granted: 2006-04-16
Abstract: Catalizador para la purificación de los gases de escape de motores diesel que contienen al menos una zeolita y adicionalmente al menos uno de los óxidos de soporte óxido de aluminio, dióxido de silicio, dióxido de titanio, dióxido de circonio y silicato de aluminio y sus óxidos mixtos y en las zeolitas y óxidos de soporte al menos uno de los metales nobles platino, paladio, rodio, iridio, oro y plata, en forma de cristalitos con una granulometría media entre 1 y 6 nm, caracterizado porque los átomos de los metales nobles tienen un grado de oxidación medio menor que +2, 5, como promedio más de tres ligandos metálicos y menos de tres ligandos oxígeno.
Patent ES-2232339-T3 (ES)
Title: Rotor para ventilador, metodo para su fabricacion y ventilador.
Inventor: NUMOTO HIRONAO
IPC: F24F7/007
Filed: 2000-03-02
Granted: 2005-06-01
Abstract: Rotor utilizado en un ventilador, que comprende: un cubo (5) y una pala (6), en el que dicha pala incluye una parte de múltiples capas (7, 8), caracterizado porque dicha parte de múltiples capas incluye una capa rígida sólo en una superficie receptora de aire en el intradós (15) de dicha pala (6) e incluye una capa de espuma moldeada (8) adherida a dicha capa rígida en el extradós (16).
Patent ES-2211406-T3 (ES)
Inventor: HASBERG JOSEF
IPC: B65H75/36
Filed: 2000-04-06
Granted: 2004-07-16
Abstract: The storage appliance such as drum is contained in a mounting frame (4) which has an axle (3) with at least one bearing in w the storage appliance is pivot mounted. The bearing consists of two tubular elements (13), a bore-hole (15) and a cone (14) at o end. The storage appliance has a tubular section (7) holding the axle and possessing a conically widening opening (11) at both e The elements' cone matches the conical ends (12) of the opening in the tubular section. The axle has at least one especially dismantleable clamping element ( 19) by which the bearing elements are moved and clamped in relation to the tubular section.
Patent ES-2215598-T3 (ES)
Inventor: LUSCHER MARCEL
IPC: B23B31/22
Filed: 2000-06-26
Granted: 2004-10-16
Abstract: The unit (1) has a chuck (1) to clamp a work piece support, with a centring pin (22) on the chuck co-operating with second positioning devices on the work piece support. The pin and second positioning devices co-operate in pairs as alignment elements and position the work piece support in three orthogonal axes and the desired angle. A clamp device (12,18) fixes the clamping force of the work piece support in position at the chuck. The clamp device has a number of clamping balls (18) and an annular groove. The line of the clamping force of the clamp device lies in a cylindrical casing surface (MF) of the chuck, which is parallel the chuck axis (Z) and intersects the centring pin and second positioning devices.
Patent ES-2244404-T3 (ES)
Inventor: FEUILLOLEY GUY
IPC: F16K31/08
Filed: 2000-01-07
Granted: 2005-12-16
Abstract: The invention relates to an asepticizable valve characterized in that said valve comprises a needle (46) provided with a core (54) that is made of a magnetic material. The invention is further characterized in that the valve comprises a front permanent magnet (30) that maintains the needle (46) in a position in which it rests on a seat when closed and a rear permanent magnet (38) ensures that the needle is maintained in a rear position corresponding to a first flow. The invention is also characterized in that the front reel (32) is arranged to the rear of the front magnet (30), in that one of the reels is provided in order to maintain the needle (46) in an advanced intermediate position corresponding to a  second flow  and the electricity supply of the reels can be controlled in such a way that the needle is displaced between the furthermost positions and the intermediate position.