baber/WOPTO huggingface dataset:
Patent JP-4062365-B2 (JP)
IPC: A61K38/00
Filed: 1997-03-14
Granted: 2008-03-19
Abstract: External guide sequence (EGS) molecules for eukaryotic RNAse P are engineered to target efficient and specific cleavage of target RNA. Engineered RNA molecules are designed and synthesized which contain specific nucleotide sequences which enable an external guide sequence for RNAse P to preferentially bind to and promote RNAse P-mediated cleavage of target RNA molecules. Short External Guide Sequence (SEGS) molecules have been constructed that, when hybridized to a target molecule, provide a minimal structure recognized as a substrate by RNAse P. The SEGS/target structure is comprised of a structures similar to the A stem and the T stem of a tRNA, the natural substrate of RNAse P. The SEGS makes up only half of these stem structures. The other half of the stem structures is provided by the target molecule. By allowing the target molecule to form more of the RNAse P substrate structure, the disclosed SEGS molecules can be significantly smaller than previous EGS molecules. This makes SEGS molecules especially useful as therapeutic agents since they are easier to manufacture and administer in quantity.
Patent JP-4339402-B2 (JP)
IPC: C07D233/02
Filed: 1997-06-30
Granted: 2009-10-07
Abstract: The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel azolidinedione derivatives of general formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them.
Patent JP-4001636-B2 (JP)
IPC: C07D213/87
Filed: 1998-04-10
Granted: 2007-10-31
Abstract: A series of activated iodo-benzamide derivatives are described as antineoplastic and antiviral drug compounds. The compounds generally possess a chelating group, a thiol trapping group and an activating group. The presumptive mechanism of action in preventing cancer cell and virus replication is through inhibition of the binding of transcription factors to zinc finger binding domains. The compounds are effective in inhibiting growth of a variety of human and animal tumor and leukemia cell lines at low concentrations.
Patent ES-2212875-B2 (ES)
Title: Sistema de seguridad para encofrados planos de obra.
Inventor: NAVARRO PEREZ ANTONIO
Filed: 2002-02-18
Granted: 2005-06-01
Abstract: Sistema de seguridad para encofrados planos de
obra. 
     Sistema de seguridad para encofrados planos de
obra, de utilidad  para el montaje de encofrados planos de obra que
se adaptan a cualquier  superficie, de forma que el sistema
comprende un primer elemento (1),  definido por un perfil (2) base,
dotado, en proximidad a un extremo libre de  su cara superior, de un
cuerpo (3) tubular en posición vertical, en proximidad  al cual
dispone, respecto de su parte interior, un cuerpo (4) que define un 
cajeado (5) central en sentido ortogonal al perfil (2) base, y un
segundo  elemento (7), definido por un perfil (8) en forma de
"T" invertida, cuyas alas  presentan una sección en "U"
quedando unidas entre sí y con la parte  central del ala horizontal
abierta, y presentando en la cara superior del ala  central en
"U" invertida un cuerpo (9) tubular y a cada lado del mismo 
presenta un tornillo (10) de presión.
Patent ES-2234355-B2 (ES)
Title: Presurizador de envases contenedores de bebidas.
Inventor: BRUCART PUIG RAMON
IPC: B65B31/04
Filed: 2002-06-21
Granted: 2006-02-16
Abstract: Presurizador de envases contenedores de
bebidas. 
     Este presurizador comprende: un capuchón interno
provisto de unos medios para su  montaje sobre la boca del envase,
de una cavidad extrema para el alojamiento de  una válvula
antirretorno; y, opcionalmente, de un vertedor lateral con válvula 
de cierre y una cánula; un actuador externo, montado coaxialmente
sobre el  capuchón interno y con posibilidad de desplazamiento
longitudinal y, una válvula  unidireccional montada de forma
ajustada entre las superficies enfrentadas del  capuchón interno y
el actuador externo y que permite la entrada de aire del  exterior
hacia el interior del presurizador durante el avance del actuador en
un  sentido e impide la salida del mismo hacia el exterior durante
el avance del  actuador en sentido opuesto contrario.
Patent ES-2217942-B2 (ES)
Title: Instalacion para la depuracion de humos y gases.
Inventor: SANCHIS GRACIA ELSA
IPC: B01D47/06
Filed: 2002-11-13
Granted: 2005-06-16
Abstract: Instalación para la depuración de humos y gases Comprende una estación de recogida de humos y gases, una estación de pulverización de agua, una estación de lavado donde se separan y eliminan partículas sólidas, líquidos y gases en suspensión, que incluye un conducto que presenta un estrechamiento Venturi, un decantador de aguas con partículas precipitadas que pasan a un sistema de depuración, y un ventilador de aspiración. La estación de pulverización incluye unos rociadores que aplican agua pulverizada sobre los humos y gases contaminados a alta presión las cuales forman pequeñas gotas que son bombardeadas contra las partículas sólidas, líquidos o gases contenidos en los humos, produciendo su rotura, arrastre y mezcla con el agua de las gotas. La presión del agua pulverizada está comprendida entre 34,5 y 200 bar y preferiblemente entre 120 y 160 bar.
Patent ES-2463216-B2 (ES)
Title: Conexiones de redes de datos en paquetes para dispositivos inalámbricos de prioridad múltiple
Inventor: GUPTA VIVEK
IPC: H04W76/00
Filed: 2013-05-10
Granted: 2015-08-04
Abstract: Se desvele un dispositivo y un procedimiento para formar una conexión de red de datos en paquetes (PDN) en un equipo de usuario (UE) configurado en modo de prioridad de acceso dual. El procedimiento comprende el envío, desde el UE a una entidad de gestión de movilidad (MME), de un mensaje de petición de conectividad PDN que incluye un indicador de sustitución de prioridad de señalización NAS para indicar que la conexión PDN tiene un modo diferente de prioridad de señalización NAS al de una conexión PDN existente. La conexión PDN existente está operativa en un primer modo de prioridad de señalización. La conexión PDN existente se desactive en el UE. En el UE se establece una nueva conexión PDN, que actúa en un segundo modo de prioridad de señalización NAS.
Patent AU-2001240264-B2 (AU)
Title: Resin composition, molding material, and molded object
Inventor: ITOU KUNINORI
IPC: C08L61/14
Filed: 2001-02-05
Granted: 2005-06-16
Abstract: A phenolic resin composition in which the phenolic resin can be smoothly cured at a low temperature while inhibiting the generation of free formaldehyde and trapping free phenol. An epoxy compound is dispersed or dissolved as a hardener in an aqueous phenolic resin solution. The epoxy compound functions not only as a hardener for the phenolic resin but as a trapping agent for free phenol. The phenolic resin has been sulfoalkylated and/or sulfialkylated so as to have improved hydrophilicity.
Patent AU-2001263487-B2 (AU)
Title: Method, apparatus and design procedure for controlling multi-input, multi-output (MIMO) parameter dependent systems using feedback LTI'zation
Inventor: VOS DAVID W
IPC: G05B9/03
Filed: 2001-05-30
Granted: 2007-03-15
Abstract: A method and apparatus are provided for controlling a dynamic device having multi-inputs and operating in an environment having multiple operating parameters. A method of designing flight control laws using multi-input, multi-output feedback LTT'zation is also provided. The method includes steps of: (i) determining coordinates for flight vehicle equations of motion; (ii) transforming the coordinates for the flight vehicle equations of motion into a multi-input linear time invariant system; (iii) establishing control laws yielding the transformed equations of motion LTI; (iv) adjusting the control laws to obtain a desired closed loop behavior for the controlled system; and (v) converting the transformed coordinates control laws to physical coordinates.
Patent AU-2001270962-B2 (AU)
Title: Phospholipid derivatives of valproic acid and mixtures thereof
Inventor: KOZAK ALEXANDER
IPC: A61K31/352
Filed: 2001-07-10
Granted: 2006-03-16
Abstract: The present invention relates to compounds, which are phospholipid derivatives of valproic acid, to compositions comprising said compounds and their use for treating epilepsy, migraine, bipolar disorders and pain.
Patent AU-2002213707-B2 (AU)
Title: Agrochemical formulation aid composition and uses thereof
Inventor: BROWN WILLIAM G
IPC: A01N25/06
Filed: 2001-10-26
Granted: 2007-01-18
Abstract: There is provided an agrochemical formulation aid composition for preparing bioactive and sprayable agrochemicals, wherein various components for the composition were selected from mineral oil paraffinic distillate and/or aromatic hydrocarbon distillate; 2N-octanol; oleyl-cetyl; alcohol polyoxyethylene (2) oleylether; polyoxyethylene (8) nonylphenolethin and/or ethoxylated tallow amine blend; lauryl sulphate; fatty alcohol alkoxylate; terpenes, diammonium phosphate; tetrasodium ethylene diamine tetracetate; cab-o-sil; fatty acid methyl ester; (C18) free fatty acid blend; N-butanol; and methyl alcohol. Also provided are methods of preparing the formulation aid composition on site by mixing various components and methods of preparing sprayable and bioactive agrochemical systems using the formulation aid and non-formulated or formulated agrochemicals. Also provided are uses of the formulation aid in preparing sprayable and bioactive agrochemical systems for controlling pests.
Patent AU-2002225862-B2 (AU)
Title: Spinal fusion methods and devices
Inventor: MCKAY WILLIAM F
IPC: A61B17/58
Filed: 2001-10-24
Granted: 2005-05-12
Abstract: Methods, devices and compositions for fusing adjacent vertebrae, and otherwise localizing bone growth, are provided. In one form of the invention, a method for fusing adjacent vertebrae includes preparing a disc space for receipt of an intervertebral disc implant in an intervertebral disc space between adjacent vertebrae, inserting the implant into the intervertebral disc space and providing an osteoinductive composition that includes an osteoinductive factor in a pharmaceutically acceptable carrier. The carrier is advantageously substantially impermeable to efflux of the osteoinductive factor and is released as the carrier is resorbed or biodegraded. Preferred carriers include a hardened, resorbable carrier, such as a calcium phosphate cement that retains at least about 50% of the osteoinductive factors greater than about 2 days. Preferred osteoinductive factors are growth factors and include bone morphogenetic proteins and LIM mineralization proteins. In alternative forms of the invention, the method may be performed without utilization of a load-bearing spinal implant by disposing the osteoinductive composition in the disc space. The method is advantageously performed on lumbar vertebrae by a posterior approach. Intervertebral fusion devices and methods for their preparation are also provided.
Patent AU-2002246078-B2 (AU)
Title: Method for the selective and collective transmission of messages in a tmn network
Inventor: BURGER ALAN
IPC: H04Q3/00
Filed: 2002-01-31
Granted: 2006-07-20
Abstract: Messages in a telecommunications management network system run on ITU-T guidelines can be selected and/or delayed over a period and collected together. To achieve this, a mass event discriminator (18) is defined as an object class and a mass event processor (20) uses its access to the mass event discriminator to forward messages exclusively from a network element to a processing system. Independent claims are also included for a network management system with a message-classifying unit and forwarding devices and for a network management device for classifying and forwarding messages.
Patent AU-2002303881-B2 (AU)
Title: Plate and method for high throughput screening
Inventor: EVERETT KEITH
IPC: C12N5/04
Filed: 2002-05-29
Granted: 2008-01-10
Abstract: A multiple well plate and method for media exchange, including a body defining a plurality of cell wells each connected via a channel to one of a plurality of aspiration holes, is provided. The cell wells contain a porous, hydrophilic frit which is suspended on a ledge above a reservoir of fluid media and supports a tissue sample. The properties of the frit wick the fluid media upwards to supply the tissue sample with nutrients for growth and proliferation. Old media is aspirated from the wells by a liquid handling device which inserts a pipette tip into the aspiration holes. The pipette tip applies a suction pressure which draws the media out of the cell well, through the channel, into the aspiration hole and out through the pipette tip. New media is dispersed through the pipette tip and directly into the cell well.
Patent AU-2002320737-B2 (AU)
Title: Method for marking digital data
Inventor: PARK SUNG-WOOK
IPC: G11B27/30
Filed: 2002-12-19
Granted: 2005-12-22
Abstract: According to the invention, in DVD Stream recording a temporarily erased flag is introduced in order to indicate a cell to be erased temporarily. Necessary time stamps are set for complete Stream Object Units (SOBUs) to be erasable, enabling on-the-fly permanent erasure without any additional view into the streams, or quick permanent erasure as well as complete reconstruction of temporarily erased parts. <IMAGE>
Patent AU-2002345008-B2 (AU)
Title: Synchronous machine
Inventor: WOBBEN ALOYS
IPC: H02K11/00
Filed: 2002-06-06
Granted: 2005-10-27
Abstract: The present invention concerns a synchronous machine with preferably salient poles with pole windings which are galvanically connected together. The invention further concerns a wind power installation and a method of monitoring a synchronous machine of a wind power installation. The object of the invention is to develop a synchronous machine and a method of operating a synchronous machine, such that the risk of a fire is reduced. A synchronous machine comprising a rotor which has a plurality of poles which are each provided with at least one respective pole winding, wherein the pole windings of a plurality of poles are galvanically connected together by means of a first conductor through which an exciter current flows, characterized in that laid substantially parallel to the first conductor is a monitoring conductor which is acted upon or which can be acted upon with a predeterminable signal, that the monitoring conductor is coupled or connected to a device for detecting the signal and that upon an interruption in the first conductor same is or can be detected by a signal variation in the monitoring conductor and the device for detecting the signal is coupled to a control device which then at least reduces and preferably switches off the exciter current through the first conductor.
Patent AU-2003203143-B2 (AU)
Title: Amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes
Inventor: PETTERSSON INGRID
IPC: C07D409/06
Filed: 2003-01-27
Granted: 2009-05-14
Abstract: Novel amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes, use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, and a method of treatment employing these compounds and compositions. The compounds show a high and selective binding affinity to the histamine H3 receptor indicating histamine H3 receptor antagonistic, inverse agonistic or agonistic activity. As a result, the compounds are useful for the treatment of diseases and disorders related to the histamine H3 receptor.
Patent AU-2003204158-B2 (AU)
Title: Slowly digestable starch product
Inventor: SHI YONG-CHENG
IPC: A23L7/10
Filed: 2003-05-13
Granted: 2007-08-30
Abstract: This patent pertains to a slowly digestible starch prepared by debranching amylose-containing starches, particularly by pullulanase or isoamylase. Such slowly digestible starches are useful in edible products, including nutritional supplements.
Patent AU-2003262754-B2 (AU)
Title: Composite prosthesis
Inventor: HARTLEY DAVID ERNEST
IPC: A61F2/06
Filed: 2003-08-21
Granted: 2007-06-21
Abstract: A prosthesis assembly for deployment in an aorta to span an aortic aneurysm. The prosthesis assembly has at least first and second members ( 2,4 ) with an end portion ( 12 ) of one member ( 2 ) to be joined to an end portion ( 24 ) of the other member ( 4 ) when in and when expanded within a lumen of a patient. Each member ( 2,4 ) has a stent arrangement ( 10,25 ) associated with a graft arrangement ( 8,26 ). The end portion of one member has at least part of its stent arrangement on the inner surface of its graft arrangement and the end portion of the other member has at least part of its stent arrangement on the inner surface of its graft arrangement. Advantageously two stents are overlapped. The joining portions of the first and second members can have the same diameter.
Patent AU-2004265662-B2 (AU)
Title: UPs as modifiers of the beta catenin pathway and methods of use
Inventor: LICKTEIG KIM
IPC: C12Q1/48
Filed: 2004-08-12
Granted: 2010-12-16
Abstract: Human SULF genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of SULF are provided.
Patent AU-2004298396-B2 (AU)
Title: MRI contrast medium composition for oral administration
Inventor: JOHANSSON NILS-OLOF
IPC: A61K49/10
Filed: 2004-11-10
Granted: 2010-06-17
Abstract: The use of a physiologically acceptable manganese (II) compound and an uptake promoter in the form of one or more amino acids for the manufacture of an MRI contrast composition for oral administration and MRI examination of the liver, in a ratio of Mn to promoter higher than that at which coordination compounds between Mn and promoter are formed to a substantial degree; an MRI contrast medium composition for such use; and MRI contrast medium kit; and a method for imaging of a mammalian liver using such contrast medium composition.
Patent AU-2004309357-B2 (AU)
Title: Alpha-hydroxy amides as bradykinin antagonists or inverse agonists
Inventor: ANTHONY NEVILLE J
IPC: C07D271/06
Filed: 2004-12-17
Granted: 2010-10-07
Abstract: α-Hydroxy amide derivatives of the general formula (I) are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway. R2a is selected from (1) a group selected from Ra. (2) (CH2)nNRbC(O)Ra. (3) (CH2)nNRbSO2Rd. (4) (CH2)nNRbCO2Ra. (5) (CH2)k-heterocycle optionally substituted with 1 to 3 groups independently selected from halogen.nitro, cyano.ORa.SRa.C1-4 alkyl and C1-3 haloakyl wherein said heterocycle is (a) a 5-membered heteroaromatic ring having a ring heteroatom selected from N.O and S. and optionally having up to 3 additional ring nitrogen atoms wherein said ring is optionally benzo-fused; or (b) a 6-membered heteromatic ring containing from 1 to 3 ring nitrogen atoms and N-oxydes thereof. Wherein said ring is optionally benzo-fused. (6) (CH2)kCO2Ra. and (7) (CH2)C(O)NRbRc. R2b is OH or a group selected from R2a; or R2a and R2b together with the carbon atom to which they are attached form a 3- to 7-membered carbocyclic ring optionally substituted with 1 to 4 groups independently selected from halogen. ORa. C1-4 alkyl and C1-4 haloalkyl.
Patent AU-2005274798-B2 (AU)
Title: Retinal dystrophin transgene and methods of use thereof
Inventor: ROGER GAEDIGK
IPC: C12Q1/68
Filed: 2005-07-15
Granted: 2011-11-17
Abstract: Duchenne muscular dystrophy (DMD) is a progressive muscle disease that is caused by severe defects in the dystrophin gene and results in the patient's death by the third decade. The present invention utilizes the Double Mutant mice (DM) as an appropriate human model for DMD as these mice are deficient for both dystrophin and utrophin die at 3 months of age and suffer from severe muscle weakness, pronounced growth retardation, kyphosis, weight loss, slack posture, and immobility. Expression from a transgene of novel human retinal dystrophin Dp260 was shown to prevent premature death and reduce the severe muscular dystrophy phenotype to a mild clinical myopathy. Electromyography, histology, radiography, magnetic resonance imaging, and behavior studies concluded that DM transgenic mice grew normally, had normal spinal curvature and mobility, and had reduced muscle pathology. EMG and histologic data from transgenic DM mice showed decreased abnormalities to levels typical of mild myopathy, while the DM mice exhibited severe abnormalities commonly seen in human dystrophinopathies. The transgenic DM mice also had measurable movement levels comparable to those of untreated mice and controls.
Patent AU-2005287482-B2 (AU)
Title: Strain of Lactobacillus acidophilus having analgesic properties in the gastrointestinal system
Inventor: PIERRE DESREUMAUX
IPC: A23L33/00
Filed: 2005-09-21
Granted: 2011-08-25
Abstract: The invention proposes the use of at least one strain of Lactobacillus acidophilus to prepare a support administered to humans or animals with an analgesic purpose in the gastrointestinal system.
Patent AU-2005316918-B2 (AU)
Title: Oral compositions for prevention and reduction of bacterial adhesion to oral surfaces
Inventor: TAO XU
IPC: A61Q11/00
Filed: 2005-11-28
Granted: 2011-12-08
Abstract: The present invention encompasses an oral composition containing an anti-adhesion agent, preferably a cysteine protease and most preferably ficin. In another aspect, the cysteine protease is in combination with one or more ingredients, such as antibacterial agent and surfactant. The anti-adhesion agent mitigates interaction between a subject oral cavity and plaque-forming materials.
Patent AU-2006207831-B2 (AU)
Title: Data communication in electronic blasting systems
Inventor: MICHAEL LOWNDS CHARLES
IPC: F42C15/42
Filed: 2006-01-24
Granted: 2011-09-15
Abstract: An electronic blasting system (10) comprising a plurality of hardware components (12.1 to 12.n), wherein at least two of components of the plurality of hardware components (20, 26) are adapted to communicate with each other over short range radio link (30).
Patent AU-2006211443-B2 (AU)
Title: Fetal movement monitoring system and fetal movement information collecting device
Inventor: NISHIHARA KYOKO
IPC: A61B10/00
Filed: 2006-02-07
Granted: 2012-02-02
Abstract: A fetus movement monitoring system easily usable at home and capable of accurately collecting more detail information on fetus movement over a long time and analyzing it and a fetus movement information collecting device are provided. The fetus movement monitoring system comprises a fetus movement information collecting device (21) including a fetus movement sensor (22) for detecting the movement of a fetus in the mother’s body, a timer (25) for outputting time information, a memory (26), and storage control means (24) which receives the output signal from the fetus movement a sensor (22) and stores in the memory (26) the waveform information on the signal outputted from the fetus movement sensor (22) during the period from the time when the level of the output signal exceeds a predetermined threshold till a predetermined time elapses along with the time information on the time, and an analyzing device (40) for performing signal waveform reproduction and fetus movement type judgment on the basis of the waveform information and the time information stored in the memory (26), creation of an occurrence pattern of fetus movement, judgment whether or not the fetus is favorable on the basis of the occurrence pattern, and display output of the judgment result to a display (42).