baber/WOPTO huggingface dataset:
Patent NZ-574666-A (NZ)
Title: A medicament inhaler holder that uses optical means to count and display the number of doses used
Inventor: SOUTHERLAND GARTH CAMPBELL
Filed: 2009-02-05
Abstract: A device for monitoring patient usage of a medicament inhaler (4) is disclosed. The device includes a housing (3), an optical dose counter (13) and an electronics control module. The housing (3) is releasably attachable to, or around, the medicament inhaler (4). The optical dose counter (13) is associated with the housing (3). The counter (13) is adapted to determine when a dose of medicament has been dispensed by transmitting optical signals through the medicament inhaler (4). The electronics control module and/or the optical dose counter is adapted to monitor and/or store information relating to patient usage of the medicament inhaler. The arrangement and construction is such that the device is attachable to the medicament inhaler (4), and subsequently operable, without any modifications required to be made to the medicament inhaler (4).
Patent NZ-592905-A (NZ)
Title: Models of thrombotic thrombocytopenic purpura and methods of use thereof
Inventor: SCHWARZ HANS-PETER
IPC: A01K67/027
Filed: 2009-10-27
Abstract: Provided is a non-human animal model suitable for testing the efficacy of a therapeutic agent in the treatment of a blood clotting disorder, said animal model comprising a circulating level of recombinant von Willebrand factor (VWF) polypeptide sufficient to induce disseminated intravascular coagulopathy and an inability to break down recombinant VWF polypeptide, said disorder characterized by the presence of one or more blood clots in said animal model, wherein said disorder in said animal model is caused by administering recombinant VWF to the animal model at a dosage with thrombogenic potential.
Patent NZ-595386-A (NZ)
Title: Peptides for treatment and diagnosis of autoimmune disease
Inventor: MATOSSIAN-ROGERS ARPI
IPC: A61K39/00
Filed: 2006-08-09
Abstract: 595386 Disclosed are peptide derived from antibodies with reactivity against a GPI linkage epitope, wherein the peptide consists of the amino acid sequence: [LKE]-[RG]-[GML-[LTY]-[LTG]-[PGN]-[DY]-[YAF] Also disclosed are methods of expressing said peptide, vaccine compositions comprising said peptide, and the use of said peptide in the production of a medicament for treating diseases such as autoimmune diseases, cardiovascular diseases, glucose intolerance, etc.
Patent NZ-598906-A (NZ)
Title: Vesicular formulations
Inventor: HENRY WILLIAM
IPC: A61K51/00
Filed: 2010-08-20
Abstract: Disclosed is the use of a vesicular formulation in the manufacture of a medicament for the treatment of inflammatory dermatoses disorders (such as atopic eczema, dishydrotic hand eczema, plaque type psoriasis, seborrheic eczema or acne vulgaris), the vesicular formulation comprising one or more phospholipids and one or more non-ionic surfactants selected from polyoxythylene sorbitans, polyhdroxyethylene stearates or polyhdroxetylene laurylethers, in the absence of a pharmaceutically active agent.
Patent NZ-616166-A (NZ)
Title: Drug delivery device
Inventor: PLUMPTRE DAVID AUBREY
IPC: A61M5/315
Filed: 2012-03-22
Abstract: Disclosed is a resettable drug delivery device which is a pen-type injector. Resettable devices usually require a large number of component parts therefore making the devices large and bulky. The drug delivery device comprises a body (9, 11) having a resettable dose setting mechanism, cartridge holder (7) and means (13, 14) for releasably coupling the cartridge holder (7) to the body (9, 11) or the dose setting mechanism. The cartridge holder (7) receives a cartridge (8) containing at least one medicinal product. The means (13, 14) for releasably coupling the cartridge holder (7) to the body (9, 11) of the dose setting mechanism comprises a lug (13) formed on the cartridge holder (7) and the corresponding groove or slot (14) formed on the body (9, 11) or dose setting mechanism. The means (13, 14) are adapted and arranged such that an initial rotational coupling movement of the cartridge holder (7) relative to the body (9, 11) or the dose setting mechanism cause the cartridge holder (7) to move in a first axial direction relative to the body (9, 11) or the dose setting mechanism. A continued rotational coupling movement of the cartridge holder (7) relative to the body (9, 11) or the dose setting mechanism cause the cartridge holder (7) to move in a second axial direction which is contrary to the first axial direction relative to the body (9, 11) or the dose setting mechanism.
Patent NZ-620238-A (NZ)
Title: Novel zinc finger-like peptide compositions as potent agents in cancer prevention and treatment
Inventor: LEE MING-HUI
IPC: C07K14/47
Filed: 2012-07-12
Abstract: Disclosed is the use of a zinc finger-like peptide comprising: at least seven amino acids, wherein the sequence of the at least seven amino acids has 85-100% identity to a sequence represented by RRSSSCK, in the manufacture of a medicament for treating cancer in a patient in need thereof, wherein the cancer does not comprise skin cancer, and the medicament is to be administered via intravenous injection.
Patent NZ-623381-A (NZ)
Title: Oral immediate release formulations for substituted quinazolinones
Inventor: SHENOY NARMADA R
IPC: A61K31/517
Filed: 2012-10-31
Abstract: Disclosed are oral immediate release solid pharmaceutical formulations comprising a quinazolinone as an active ingredient and (i) from about 10% w/w to about 85% w/w of microcrystalline cellulose; (ii) about 4% w/w of sodium starch glycolate as a disintegrant; (iii) about 0.5% w/w of magnesium stearate; and (iv) about 2.5% w/w of colloidal silicon dioxide as a glidant. The pharmaceutical formulations are useful for regulating the expression of apolipoprotein A-I (ApoA-I) and as BET inhibitors, for the treatment and prevention of cardiovascular disease, and cholesterol- or lipid-related disorders, including, for example, metabolic syndrome, inflammatory disease, Alzheimer’s disease, atherosclerosis, diabetes, and cancer. The pharmaceutical active ingredient is selected from: 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)quinazolin-4(3H)-one; 2-(3-chloro-4-(2-hydroxyethoxy)phenyl)-5, 7 -dimethoxyquinazolin-4(3H)-one; 2-(4-(2-hydroxyethoxy)-3-methoxyphenyl)-5,7-dimethoxyquinazolin-4(3H)-one; 2-(4-hydroxy-3-(2-hydroxyethyl)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one; 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethylquinazolin-4(3H)-one; 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5-methoxyquinazolin-4(3H)-one; 2-(4-(2-hydroxyethoxy)-3-methylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one; 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one;
Patent NZ-700025-A (NZ)
Title: A process for detection and optional quantification of an analyte
Inventor: SENGUPTA NILANJAN
IPC: G01N33/53
Filed: 2013-02-14
Abstract: This invention relates to the detection and optional quantification of analyte in a biological sample, for in a case where the analyte is susceptible to forming a complex that makes it problematic to detect and quantify the analyte. In a preferred embodiment of the invention the process involves providing a modified citrate buffer to the sample prior to carrying out assay for said detection and optional quantification of the analyte within the biological sample. The buffer comprises sodium citrate, citric acid, polysorbate 20 and HCl, has a pH of 2.5-3.8 and is such that it facilitates dissociation of the complex.
Patent NZ-703323-A (NZ)
Title: Acrylamide compounds as histamine h3 receptor ligands
Inventor: NIROGI RAMAKRISHNA
IPC: C07D401/12
Filed: 2012-12-05
Abstract: The present invention relates to novel acrylamide compounds of formula (I), and their pharmaceutically acceptable salts and process of their preparation. The compounds of formula (I) are useful in the treatment of various disorders that related to Histamine H3 receptors, including cognitive deficits in schizophrenia, narcolepsy, obesity, attention deficit hyperactivity disorder, pain and/or alzheimer’s disease.
Patent NZ-704471-A (NZ)
Title: Oxygen scavenging plastic material
Inventor: Fava ‘flavio
IPC: C08K5/3435
Filed: 2013-09-11
Abstract: The invention relates to the use of an additive as oxygen scavenger in a plastic material, wherein (a) the plastic material is a polyester, a polyolefin, a polyolefin copolymer or a polystyrene, and the additive is (b) a compound having a comprising a group of formula (A) and (c) a transition metal catalyst. The invention allows for improved gas barrier plastic composition which are particularly useful in packaging industry.
Patent NZ-715328-A (NZ)
Title: Method and apparatus for determining position for a permanent magnet elevator motor
Inventor: BACKMAN JOHN
IPC: H02P6/04
Filed: 2014-07-08
Abstract: A system for determining the angular position of a synchronous motor includes an encoder with a friction wheel engaging a rotating surface of the motor. The friction wheel is spun by the rotation of the motor, and the encoder generates a signal corresponding to the angular position of the friction wheel. To compensate against accumulated errors arising from reliance upon the signal generated by the encoder, the invention utilizes an independent sensor to generate a pulse once per revolution of the motor. The independent sensor detects the presence of a target on the rotating surface of the motor and generates the pulse when the target is proximate to the sensor. A controller receives the signal corresponding to the angular position of the friction wheel as well as the pulse generated by the independent sensor to determine the angular position of the motor. Accordingly, the controller compensates the angular position of the motor each time the pulse is generated, correcting accumulated position error.
Patent NZ-723300-A (NZ)
Title: Compositions for the prevention and/or treatment of pathologies associated with alpha-glucosidase
Inventor: MAUGARD THIERRY
IPC: A61P3/10
Filed: 2015-02-18
Abstract: The invention relates to a composition comprising at least one XAP peptide, in which X is absent or a valine, for use thereof in preventing and/or treating hyperglycemia by inhibiting alpha-glucosidase. The invention also relates to the use of a hydrolysate of at least one protein, said protein comprising or consisting of at least 0.05% to less than 5% or of at least 5% of XAP units, in which X is absent or a valine, for use thereof in preventing and/or treating hyperglycemia by inhibiting alpha-glucosidase.
Patent NZ-725595-A (NZ)
Title: Compounds for treating brain cancer
Inventor: MEHRLING THOMAS
IPC: A61P35/04
Filed: 2015-03-26
Abstract: There is provided a compound of formula I or a pharmacologically acceptable salt thereof: for use in the treatment of a brain cancer selected from a MGMT positive astrocytic brain tumour, a metastatic brain cancer and primary CNS lymphoma and a method of treating said brain cancers in a patient in need thereof comprising administering to the patient said compound of formula I or a pharmacologically acceptable salt thereof.
Patent NZ-725966-A (NZ)
Title: N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide hydrochloride salts
Inventor: SHI BING
IPC: C07D239/42
Filed: 2015-06-11
Abstract: The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.
Patent NZ-733113-A (NZ)
Title: Methods of producing long acting ctp-modified growth hormone polypeptides
Inventor: HERSHKOVITZ OREN
IPC: C07K14/61
Filed: 2015-12-10
Abstract: Disclosed herein is a method for manufacturing a recombinant human growth hormone (h GH) modified by a CTP extension in a mammalian cells culture system. The modified-CTP hGH polypeptide of the current invention consists of one CTP attached to the amino terminus of the hGH and two CTPs attached to the carboxy terminus of the hGH (CTP-hGH-CTP-CTP) wherein the CTP units comprise high levels of O-linked glycans. In particular, the present invention relates to a MOD-4023 protein (CTP-hGH-CTP-CTP) comprising 4-6 O-linked glycans per CTP, resulting in glycosylation at between 13-18 O-linked glycosylation sites, wherein the protein modified with 15 glycosylation sites is the most intense. The highly glycosylated form of MOD-4023 results in longer extension of the growth hormone half-life.
Patent NZ-738187-A (NZ)
Title: Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same
Inventor: LEE HYUNHO
IPC: A61K31/4375
Filed: 2016-06-03
Abstract: The present invention relates to novel tricyclic derivative compounds of Formula I, and more specifically to tricyclic derivative compounds, optical isomers thereof, racemates thereof, or pharmaceutically acceptable salts thereof, which have excellent activity against PARP-1, tankyrase-1 or tankyrase-2. The tricyclic derivative compounds, optical isomers thereof, racemates thereof or pharmaceutically acceptable salts thereof according to the present invention have inhibitory activity against PARP-1, tankyrase-1, or tankyrase-2, and thus can be effectively used for the prevention or treatment of neuropathic pain, neurodegenerative diseases, cardiovascular diseases, diabetic neuropathy, inflammatory diseases, osteoporosis, or cancer.
Patent PT-105455-A (PT)
Title: Tratamento de águas residuais da indústria de queijo mediante processos em série de precipitação química, neutralização natural e biodegradação aeróbia
Inventor: CARVALHO MARIA DE FATIMA NUNES DE
IPC: B01D61/16
Filed: 2010-12-22
Abstract: A APLICAÇÃO DE PROCESSOS EM SÉRIE DE CLARIFICAÇÃO (PRECIPITAÇÃO QUÍMICA (PQ) SEGUIDO DE SEDIMENTAÇÃO POR CAMADAS), ESTABILIZAÇÃO NATURAL DE PH, POR CARBONATAÇÃO A PARTIR DO CO2 DO AR E BIODEGRADAÇÃO AERÓBIA (BA) CONSTITUEM UMA ALTERNATIVA EFICIENTE, ECONÓMICA E DE FÁCIL APLICAÇÃO NO TRATAMENTO DE ÁGUAS RESIDUAIS DA INDÚSTRIA DE QUEIJO (ARIQ), QUER FRESCAS QUER ARMAZENADAS. A ETAPA DE PRECIPITAÇÃO OCORRE PELA ADIÇÃO DE CAL HIDRATADA ATÉ À OBTENÇÃO DE UM PRECIPITADO ABUNDANTE QUE APRESENTA SEDIMENTAÇÃO POR ZONAS. A ETAPA DE CLARIFICAÇÃO PERMITE A OBTENÇÃO DE UM EFLUENTE CLARIFICADO E TRANSPARENTE, BIODEGRADÁVEL, COM REDUZIDO TEOR DE SÓLIDOS EM SUSPENSÃO,TURVAÇÃO, FÓSFORO, AZOTO, PROTEÍNAS, ÓLEOS E GORDURAS. O EFLUENTE CLARIFICADO SE COLOCADO AO ABRIGO DO AR É ESTÁVEL E MANTÉM AS SUAS PROPRIEDADES AO LONGO DO TEMPO. QUANDO EXPOSTO AO AR O PH DESCE ATÉ PRÓXIMO DA NEUTRALIDADE POR REACÇÃO COM O CO2 DO AR E PRECIPITAÇÃO DE CACO3. A ETAPA DECLARIFICAÇÃO PERMITE A APLICAÇÃO DO PROCESSO DE BA COM REDUÇÃO DO TEMPO DE RETENÇÃO (31-74%) E DA CONTAMINAÇÃO ORGÂNICA (100%) BEM COMO SE VERIFICA A SEDIMENTAÇÃO DAS LAMAS POR ZONAS.
Patent RO-86320-A (RO)
Inventor: WONG DAVID T
IPC: C07D491/04
Filed: 1983-02-28
Abstract: This invention relates to certain amino-5,6-diaryl-1,2,4--triazines and -pyrazines useful as activators of GABA and benzodiazepine binding.
Patent RU-94025330-A (RU)
Inventor: PIKUL V N
IPC: F03D3/04
Filed: 1994-07-06
Abstract: FIELD: wind-power engineering. SUBSTANCE: suspended from air intake guide ring is light-weight shell of convex-concave profile, turbine blading shell is transformed here with its exhaust edge into friction connection; cylindrical base of mentioned air intake has circular lip under drain lower edge; convex band edge of shell embraces mentioned edge with annular clearance so that this clearance is larger than that between lip and upper part of concave band; shell suspension ropes are uniformly arranged over circle and their top ends are inclined to turbine shaft; slot-like riffles are provided on inner surface of friction connection. Wind head acts on front sector of shell and on its side insert or sails built in concave outer part of mentioned shell and displaces suspended assembly in the direction of air flow. Shell runs into lip edge and inclines. In the process, windward part goes down and opposite side of same shell goes up. This transforms annular clearance between drain and convex band into vertical slits. Wind forced into front slit flows over cylindrical base and is expelled through rear slit by means of shell. In this way, wind jets charge shadow spiral channels. EFFECT: improved efficiency of weak wind utilization for low-power windmills.
Patent RU-94025764-A (RU)
Inventor: ATROSHCHENKO V A
IPC: H02M7/42
Filed: 1994-07-11
Abstract: FIELD: power conversion engineering; controlling and adjusting voltage inverter using beat method for shaping sine-wave output voltage. SUBSTANCE: novelty is that device has efficiency adjusting circuit set up of inverter input and output current sensors, multipliers, ripple filters, divider, adding assembly, Pl regulator, and relevant connections. EFFECT: reduced switching loss, improved efficiency.
Patent RU-94029660-A (RU)
Inventor: ABRAMOV A A
IPC: C23F13/04
Filed: 1994-07-29
Abstract: FIELD: electrochemical protection of underground facilities. SUBSTANCE: aggregate has cathode protection station, that has a row of identical channels 1 with input rectifiers 10, storage devices 16, converters 12, summing transformer 13 and output rectifiers 15 and output storing devices 16. Station has prefabricated bars 5, 6, 7, 8, 9, that provide transversal galvanic connections. Signals from current measuring transformers 14 outputs and from comparison electrode 18 output are fed to input of control unit 3. Control unit 3 controls operation of converters 12. EFFECT: increased reliability of aggregate work and quality of protection. 4 cl, 1 dwg
Patent RU-94036737-A (RU)
Inventor: GRANOVSKIJ G P
IPC: B23P19/04
Filed: 1994-09-29
Abstract: FIELD: automotive industry; clutches of heavy truck engines. SUBSTANCE: article is placed on plate and pressed to cover, and adjusting rods are driven to working sections of article levers. Depending on position of levers, i.e. exceeding or less than tolerable size, lever nuts are turned on or backed off by separate drives. When tolerable size is obtained, adjusting rods of spindle head are moved upwards and levers are prepared for upsetting. For this purpose cross is brought into contact with working sections of levers and 10-fold upsetting is carried out by moving cross rod upwards and downwards. After running-in of article members, checked size slightly changes, making it necessary to carry out final adjustment of size. With article mounted on engine, clutch accurately and reliably goes within the limits of engine overall dimensions and provides more reliable operation of engine. EFFECT: enhanced reliability of operation.
Patent RU-94038097-A (RU)
Inventor: KLJUCHKIN V V
IPC: C11B1/10
Filed: 1994-09-30
Abstract: FIELD: production of fat and protein. SUBSTANCE: method involves production of suspension of ground raw materials with water, treatment thus prepared suspension by ferments followed by its separation into fractions. Mentioned above raw material is ground in aqueous medium to size 100-200 μm. EFFECT: increases yield of desired products.
Patent RU-94039325-A (RU)
Inventor: ALEKSANDROV V V
IPC: H02M1/16
Filed: 1994-09-29
Abstract: FIELD: conversion equipment; diagnostics and protection of secondary pulsed power sources, including transistor ones. SUBSTANCE: energy is transmitted in the form of sinusoidal current. The value of the current and the rate of its change in the circuit of an inverter are measured. Measurement results are converted to the form: y = kI, where y is the converted signal; k is the constant; Iis the amplitude of the sinusoidal current in the inverter circuit. The measurement and conversion results are compared with a reference scale. Basing on results of the comparison, decision is made about actuation of executing mechanisms. Device has a current sensing unit and a current rate sensing unit in the resonance circuit of an inverter, a converter, a comparison circuit and a decision-making circuit. The converter has two reduction circuits, two squarers, a summator and a square-rooting circuit. The comparison circuit uses a reference scale. Outputs of the sensing units are connected with inputs of the respective reduction circuits. First outputs of the reduction circuits are connected with two inputs of the comparison circuits, their second outputs connected with inputs of the respective squarers. Outputs of the squarers are connected with the summator inputs. The summator output is connected with input of the square-rooting circuit whose output is connected with the third input of the comparison circuit. Fourth input of the comparison circuit is connected with a reference voltage source. Outputs of the comparison circuit are connected with inputs of the decision-making circuit. EFFECT: early and comprehensive diagnostics of inverter power circuits, which enables emergency switching within the range of safe operating conditions without using current limiters or damping circuits; better justified decision making to eliminate any accidental state by means more suited to that situation; simplified power circuits; improved thermal conditions; higher reliability and reduced weight and size of inverters; increased transistor loading; reduced cost of inverters and power sources on their basis.
Patent RU-94040318-A (RU)
Inventor: BARANOVA T I
IPC: E02D27/12
Filed: 1994-11-01
Abstract: FIELD: civil engineering. SUBSTANCE: foundation mat represents a system of such two pieces as truncated hollow pyramid with a cut in smaller base for being put on the pile and slab secured to larger pyramid base. Grating slab has a rest around its contour that covers the pyramid in a circle and takes thrust efforts arising from loading the foundation mat. EFFECT: lower materials consumption.
Patent RU-94042469-A (RU)
Inventor: SHTEFEN RANSOM
IPC: B64G1/00
Filed: 1994-01-13
Abstract: FIELD: rocket engineering. SUBSTANCE: control gear is designed for control over behavior of rocket carrier which is fitted with drive and useful load in flight. Rocket carrier has at least one control system and also at least one control element to change flight trajectory transverse to longitudinal axis of rocket. Control element is manufactured in the form of controlling wing mounted for turning which is located in side zone of rocket carrier. Actuating element is connected to controlling wind which is adjusted by control system so that measurement results of load of side wind prepared by sensitive elements are converted to compensate for lateral forces into setting of specified position of controlling wing. EFFECT: enhanced reliability of flight control.
Patent RU-94043724-A (RU)
Inventor: NIKOLAEV V A
IPC: B23P19/02
Filed: 1994-12-14
Abstract: FIELD: mechanical engineering; instrument engineering, electromechanical devices for assembling connections with interference and thrust against shoulder. SUBSTANCE: having press-fitted ring-type workpiece onto shaft with thrust against shoulder and switching off supply voltage, series of pulses of length tare formed on high-torque DC motor of electromechanical press by means of motor control system. These pulses provide repeated final step press-fitting operations. Each time when limiting value of current tin motor supply circuit is reached, drive is switching off to provided time delay tmaking it possible for shaft-ring system occupy the position where there is no mechanical stresses along axis of joint. EFFECT: improved quality of joint.