baber/WOPTO huggingface dataset:
Patent CA-3003102-A1 (CA)
Title: Dosage regimens of melphalan flufenamide for treatment of multiple myloma
Inventor: LINDBERG JAKOB
IPC: A61K31/223
Filed: 2016-12-01
Abstract: The present invention providesmelflufen (melphalan flufenamide; L-Melphalanyl-4- fluoro-L-phenylalanine ethyl ester), or a salt thereof, for use in the treatment or prophylaxis of multiple myeloma, wherein a dosage of melflufen (excluding the mass of any salt) is administered as a parenteral dosage at an infusion rate of 1.0 to 1.8 mg/min. Also provided is melflufen, or a salt thereof, for use in the treatment or prophylaxis of a cancer, for example a solid cancer, wherein a dosage of melflufen is administered as a parenteral dosage at an infusion rate less than 0.8 mg/min (for example 0.3 to 1.0 mg/minor for example 0.3 to 0.8 mg/min).
Patent CA-3003834-A1 (CA)
Inventor: VONDRELL RANDY M
IPC: H02K16/00
Filed: 2018-05-03
Abstract: A propulsion system includes a combustion engine, a propulsor, and an electric machine configured to either be driven by the combustion engine or configured to drive the propulsor. The electric machine defines an axis. The electric machine includes a rotor extending along and rotatable about the axis, and a stator having a plurality of winding assemblies, the plurality of winding assemblies spaced along the axis of the electric machine, each winding assembly operable with the rotor independently of an adjacent winding assembly during operation of the electric machine.
Patent CA-3005125-A1 (CA)
Inventor: DEB AMITABHA
IPC: C12N7/02
Filed: 2016-11-18
Abstract: The invention provides lentiviral preparations containing a sulfonic acid buffer, such as 1,4-piperazinediethanesulfonic acid (PIPES), 2-(N-morpholino)ethanesulfonic acid (MES), and 3-morpholinopropane-1 -sulfonic acid (MOPS), a sodium citrate buffer, or a phosphate buffer. The invention additionally encompasses methods of lentiviral purification as well as methods of transducing human cells.
Patent CA-3005151-A1 (CA)
Inventor: SCHALLER MICHAEL PAUL
IPC: A61F2/16
Filed: 2016-09-16
Abstract: Un contenant pour implant (120) conçu pour contenir un implant oculaire est décrit ici. Le contenant pour implant peut s'accoupler de manière amovible à un dispositif de pose d'implant et permettre au moins l'alignement partiel du dispositif de pose avec l'implant oculaire pendant le chargement de l'implant oculaire sur le dispositif de pose.
Patent CA-3007658-A1 (CA)
Inventor: CHADHA AJAY
IPC: D02G3/36
Filed: 2016-12-16
Abstract: A textured fabric for an implantable bioprosthesis is provided. The textured fabric can include a woven base layer and a plurality of loops projecting from the woven base layer. The plurality of loops are formed from a composite core-sheath yarn. The core can be made of a material that is different from the sheath. The core material can be selected to impart strength and resiliency to bending and the sheath material can be selected to impart a larger surface area or texture that facilitates cellular or tissue in-growth.
Patent CA-3008712-A1 (CA)
Inventor: RUUTTU JARI
IPC: A22C25/16
Filed: 2016-12-16
Abstract: A method for preparing a fish product. In the method, a slaughtered fish is filleted in pre-rigor state, skin is removed from the fillet in pre-rigor state, the skinless fillet is arranged in a pre-salting process in pre-rigor state and allowed to remain there for the pre-salting period, the fillet is removed from the pre-salting process, the fillet is arranged in its transport package, in which it is subjected to a second salting process, and the fillet is allowed to remain in the transport package for at least one day.
Patent CA-3013586-A1 (CA)
Inventor: FRAZER BRANDON
IPC: B64F5/60
Filed: 2018-08-08
Abstract: Various embodiments of the present disclosure provide an aircraft engine monitoring system. Generally, the aircraft engine monitoring system includes an engine monitoring device and one or more sensors configured to sense engine parameters of an engine of an aircraft and to generate and send signals representing the sensed engine parameters to the engine monitoring device, which stores them as engine performance data. An external device is communicatively connectable to the engine monitoring device to retrieve the engine performance data if both (1) the engine monitoring device determines that the external device is a trusted device and (2) the external device determines that the engine monitoring device is a trusted device, the engine monitoring device is configured to encrypt and securely transmit some or all of the engine performance data to the external device.
Patent CA-3014060-A1 (CA)
Inventor: STEWART DOUGLAS
IPC: A23K20/163
Filed: 2017-02-23
Abstract: The present disclosure relates to coextruded pet food compositions and/or to methods for producing the same. The disclosure provides, for example, a method for producing a pet food, comprising: (i) extruding a first composition from a first extruder through a die at a first rate of exit from the die; and (ii) extruding a second composition from a second extruder through the die at a second rate of exit from the die, wherein the first rate of exit from the die is higher than the second rate of exit from the die, to produce a coextruded pet food that comprises about 30% to about 50%, by weight, of the first composition and about 50% to about 70%, by weight, of the second composition. Moreover, the coextruded pet food compositions of the present disclosure may include, for example, at least about 3% cheese and/or at least about 5% bacon.
Patent CA-3017278-A1 (CA)
Title: Drill chuck adaptor system and method
Inventor: DRAGON STEVE W
IPC: B23B51/12
Filed: 2018-09-13
Abstract: A drill chuck adaptor system including: a drill chuck adaptor tool including a socket body, a lug-receiver, and a threaded-member; as such the drill chuck adaptor system enables the drill chuck adaptor tool for effective use. The drill chuck adaptor tool is defined by the socket body, the lug-receiver, and the threaded-member; the lug-receiver, and the threaded-member extending outwardly from (on) opposing ends of the socket body. The socket body is removably couplable to an impact-driver-tool via a lug of the impact-driver-tool being received by the lug-receiver and the threaded-member is able to be removably coupled to a drill chuck such that the drill chuck is able to be driven via the impact-driver-tool.
Patent CA-3018780-A1 (CA)
Inventor: ROBINSON JOHN
IPC: A61M25/02
Filed: 2017-03-20
Abstract: A medical component securement device includes a strap and a first medical component holder attached to the strap. The strap includes a number of openings spaced along the length of the strap that enables one or more auxiliary medical component holders to be removably attached to the strap. The first medical component holder may include two members that pivot about a pivot axis to open and close the first medical component holder.
Patent CA-3019504-A1 (CA)
Title: Bees attracting and bee tranquilizing composition and their use in agriculture, horticulture and apiculture
Inventor: SWIETOSLAWSKI JANUSZ
IPC: A01N35/02
Filed: 2016-04-19
Abstract: The invention relates to a bee attracting and bee tranquilizing composition having a form of an oil/water emulsion in aqueous phase, wherein the oil phase contains citral (3,7-dimethylocta-2,6-dienal), eugenol (4-aliyl-2-methoxyphenol) and an oil carrier in an amount of 10% to 50% by weight of the composition, the weight ratio of citral to eugenol is in a range from 1 to 10, and more preferably in a range from 1.7 to 5, and the aqueous phase contains a sweetener in an amount of 15% to 60% by weight based on the total weight of the aqueous phase. Said sweetener is preferably selected from the group including: sacharose, fructose, glucose, sugar, inverted sugar syrup, maltose syrup and mixtures thereof. The invention also relates to methods and uses of such a composition for increasing the productivity of a crop area requiring bee pollination in agricultural and/or horticultural environments, as well as methods and uses of such a composition for increasing the efficiency of introducing a replacement queen bee to a new bee colony, of joining bee colonies and for tranquilizing bees in apiculture applications.
Patent CA-3019949-A1 (CA)
Inventor: DALLAN ANDREA
IPC: B23K26/08
Filed: 2018-10-05
Abstract: The present invention concerns an apparatus for laser or plasma cutting of pieces P from laminar material wound in coil, comprising: - a cutting station 10, provided with at least one cutting head 11 movable within an operative cutting area 12, located above a receiving cavity 13 for the cutting swarf T; - means 21, 22 for positioning a portion of the laminar material in the operative area on a cutting plane m located above the receiving cavity 13, wherein such positioning means are intended to keep the portion blocked on the cutting plane during cutting operations, suspended in the air and longitudinally stretched above the cavity; and - an electronic control unit 200. The apparatus comprises at least one movable device 100 for selective collection of the machined pieces P. The movable device 100 defines a continuous collection surface 101 and is movable underneath the cutting plane and parallel to it between an active position, wherein it is positioned inside the operative cutting area closing the cavity between the cutting plane and the bottom of the cavity, and a passive position, wherein it is positioned outside the operative cutting area outside the cavity. The electronic control unit is programmed to control the movement of said movable collection device 100 between the two positions in coordination with the execution of the cutting operations, in such a way that that the movable device is in the passive position when the cutting head is performing cutting operations that generate swarf T, letting such swarf free to fall by gravity inside the cavity 13, and is instead in the active position when the cutting head is performing cutting operations which lead to the complete detachment of the pieces P from the skeleton S so that such pieces P are collected by the movable device separately from the swarf T and from the skeleton, which is retained by the positioning means on the cutting plane m above the movable device 100.
Patent CA-3020258-A1 (CA)
Inventor: SETO MASAHIRO
IPC: C21D8/00
Filed: 2017-04-06
Abstract: An austenite stainless steel that has a chemical composition containing, in mass%, 0.015% or less of C, 1.00% or less of Si, 2.00% or less of Mn, 0.05% or less of P, 0.030% or less of S, not less than 16.0% but less than 22.0% of Cr, 11.0-16.0% of Ni, 2.5-5.0% of Mo, not less than 0.07% but less than 0.15% of N, 0.20-0.50% of Nb, 0.005-0.040% of Al, 0-0.080% of Sn, 0-0.0060% of Zn, and 0-0.030% of Pb, the remaining portion being Fe and impurities, and that satisfies [MoSS/Mo = 0.98] (MoSS: amount of Mo solids dissolved in Mo steel).
Patent CA-3021025-A1 (CA)
Inventor: ZUNIGA SAGREDO JUAN
IPC: B64C3/26
Filed: 2018-10-16
Abstract: The present invention provides an access cover for an aircraft hole that comprises a plurality of holes, an inner surface, a plurality of first projections protruding from the inner surface, and a plurality of fixing means configured to fix the access cover to a supporting structure of the aircraft hole. The fixing means comprises a male fixing element having an outer threaded surface, the male fixing element being configured to pass through a hole, and a locking element comprising a threaded hole and an extended portion, wherein the outer threaded surface of the male fixing element is configured to thread with the threaded hole of the locking element.
Patent CA-3022494-A1 (CA)
Inventor: ADAMS RALPH
IPC: C07K16/18
Filed: 2017-04-28
Abstract: The present disclosure relates to a method of modulating the half-life of a binding domain specific to a serum carrier protein by mutating the sequence and a modulated binding domain specific to a serum carrier protein.
Patent CA-3022513-A1 (CA)
Inventor: OLSON ERLEND
IPC: B64G1/10
Filed: 2017-05-03
Abstract: A system for re-using GEO-allocated communications spectrum in a LEO satellite constellation based communications system, such that the LEO satellite originated signals will not appear in the beam-width of GEO-pointed earth station antennas, and satellites configured to provide communications by manipulating their respective beam transmissions, which may include a forward beam and rearward beam whose angles are controlled to project the beam and reduce or eliminate the potential for interference with GEO-pointed earth station antennas. The system and LEO satellites may provide substantially 100% coverage of an earth station located anywhere on the surface of the earth, without coordination with the GEO satellites or GEO-pointing ground stations. The system also may provide earth stations that are configured to enhance the isolation between the GEO communications system and the LEO communications system using the same spectrum to reduce the potential for GEO-pointed earth station antennas from picking up the LEO communication.
Patent CA-3024440-A1 (CA)
Inventor: BEK ROBIN
IPC: A61M1/00
Filed: 2014-04-08
Abstract: A fluid management system for use in a tissue resection procedure includes a controller. An inflow pump is operated by the controller and configured to provide fluid inflow through a flow path to a site in patient's body. An outflow pump is operated by the controller and configured to provide fluid outflow through a flow path from the site in patient's body. A motor driven resecting device may be provided for resecting tissue at the site. The controller is configured to actuate an inflow pump and an outflow pump in response to various signals and various algorithms are provided to provide malfunction warnings and assure safe operation.
Patent CA-3025657-A1 (CA)
Inventor: RUFINO BENOIT
IPC: C03C17/34
Filed: 2017-06-14
Abstract: The invention relates to a glass sheet including a tempered mineral glass substrate having, on one of the surfaces thereof, a transparent coating with low emissivity and, on said coating, a layer of enamel containing one or more ceramic pigments, the layer of enamel covering only one portion of the low-emissivity layer and leaving another portion thereof free, characterised in that at least 50 wt %, preferably at least 80 wt %, and in particular at least 95 wt %, of the ceramic pigments are selected among the ceramic pigments that reflect near infrared radiation (NIR) having a reflectance at 1000 nm, determined according to standard ASTM E 903, no lower than 40 % and a clarity L* of less than 30. The invention likewise relates to a method for manufacturing such a sheet and to an oven or refrigerator door containing such a sheet.
Patent CA-3026823-A1 (CA)
Inventor: BERESINI MAUREEN
IPC: C12N9/64
Filed: 2017-06-21
Abstract: The invention provides PCSK9 inhibitors, compositions comprising the PCSK9 inhibitors, and methods of identifying and using the PCSK9 inhibitors.
Patent CA-3028581-A1 (CA)
Title: Composition for treatment and/or nutrition of poultry
Inventor: CONNERTON IAN
IPC: A23K10/18
Filed: 2017-06-30
Abstract: A composition for the treatment and/or nutrition of poultry such as broiler chickens is disclosed as comprising (i) one more probiotics which are commensal selected from one or more of Bifidobacterium animalis, Collinsella tanakaei, Lactobacillus reuteri, Anaerostipes, Lactobacillus crispatus, Pediococcus acidilactici, Lactobacillus pontis, Faecalibacterium prausnitzii, Coprococcus catus, Roseburia intestinalis, Anaerostipes butyraticus, Butyricicoccus, Lactobacillus johnsonii, and Ruminococcus sp.; and (ii) a prebiotic material. The application also discloses the use of such a composition for the treatment of enteric disease in poultry, such as necrotic enteritis.
Patent CA-3028826-A1 (CA)
Inventor: FARRELL RON
IPC: A61M16/00
Filed: 2017-06-21
Abstract: A sedation device (1) has a housing (2) divided internally into a ventilator chamber (3) and an associated evaporator chamber (4) which overlap and are separated by a filter (5) mounted between the chambers (3, 4) and forming a common gas-permeable dividing wail between the chambers (3, 4), An inlet port (7) is provided at one end of the ventilator chamber (3) at a top of the housing (2) for connection to a patient ventilator in use. An outlet port (8) on the evaporator chamber (4) can be connected via a breathing tube to a patient. An evaporator (10) is mounted within the evaporator chamber (4) for delivery of a volatile sedative into the evaporator chamber (4) during use.
Patent CA-3028981-A1 (CA)
Inventor: HULSEMAN RALPH ALLEN
IPC: B81C1/00
Filed: 2017-06-23
Abstract: A label with improved physical properties comprising: a base layer having a microstructured area; a composite microstructure having a first, second and third set of microstructures disposed on the microstructured area; a dry lift force attributable to the composite microstructure greater than 7 pounds according to lift testing; a wet lift force attributable to the composite microstructure greater than 7 pounds according to lift testing; an adhesive layer affixed to the base layer for affixing the label to a container; and, thereby providing a microstructured label having improved gripping physical properties that can be affixed to a container.
Patent CA-3029576-A1 (CA)
Title: Procede d'amelioration de la qualite et de la quantite de la progeniture chez des mammiferes
Inventor: KENNEDY VICTORIA C
IPC: A61B5/00
Filed: 2017-06-30
Abstract: La présente invention concerne des procédés permettant de prédire la fertilité et/ou de confirmer le succès de la gestation et/ou de la taille des portées chez des mammifères. L'invention concerne également de nouveaux procédés et de nouveaux dispositifs pour tester sur le terrain des échantillons de mammifères en vue de la réussite de la gestation et de la prospérité de la reproduction (fécondité).
Patent CA-3031194-A1 (CA)
Inventor: MARASCO WAYNE A
IPC: C07K16/28
Filed: 2017-07-24
Abstract: The present invention comprises human monoclonal antibodies that bind to GITR (also known as glucocorticoid-induced tumor necrosis factor receptor). Binding of the invented antibody to GITR inhibits binding of its ligand, GITR-L, and can be used to treat cancer.
Patent CA-3032528-A1 (CA)
Inventor: EMIG CHRISTOPHER J
IPC: C07K16/00
Filed: 2017-09-14
Abstract: The present invention relates generally to the field of immune binding proteins and method for obtaining immune binding proteins from genomic or other sources. The present invention also relates to nucleic acids encoding the immune binding proteins in which the natural multimeric association of chains is maintained in the nucleic acids and the immune binding proteins made therefrom. For example nucleic acids encoding antibodies that are amplified from a B-cell using the methods of the invention maintain the natural pairing of heavy and light chains from the B-cell. This maintenance of pairing (or multimerization) produces libraries and/or repertoires of immune binding proteins that are enriched for useful binding molecules.
Patent CA-3033133-A1 (CA)
Title: Compositions for stimulation of mammalian innate immune resistance to pathogens
Inventor: DICKEY BURTON
IPC: A61P31/12
Filed: 2010-03-25
Abstract: Embodiments of the invention are directed to methods of treating, inhibiting or attenuating a microbial infection in an individual who has or is at risk for developing such an infection, comprising the step of administering an effective amount of a TLR9 agonist and a TLR 2/6 agonist to the individual.
Patent CA-3034508-A1 (CA)
Inventor: AHONIEMI HANNU
IPC: D21F1/66
Filed: 2016-09-01
Abstract: A process and an apparatus for producing nonwoven materials are disclosed. The process comprises the following steps: a) providing a three-phase (gas-liquid-solid) suspension containing air, water, fibrous material and a surfactant, b) depositing the suspension onto a moving carrier sieve to produce a fibrous web on the carrier, c) removing aqueous residue of the suspension through the carrier sieve, d)conveying the aqueous residue through one or more phase separation tanks in an essentially horizontal direction while providing a depressurised headspace above the aqueous residue, e) recycling the aqueous residue conveyed in step d) to step a), f)preferably pre-integrating the fibrous web.
Patent CA-3035377-A1 (CA)
Title: Methods and compositions for targeting t-cell cancers
Inventor: MARKOVIC SVETOMIR N
IPC: A61K31/337
Filed: 2017-08-31
Abstract: Described herein are compositions of binding agents and carrier proteins, and at least one therapeutic agent, wherein the binding agents are capable of binding an antigen expressed on T-cells and methods of making and using the same, in particular, as a T-cell cancer therapeutic. Also described are lyophilized compositions of binding agents and carrier proteins, and at least one therapeutic agent, and methods of making and using the same, in particular, as a T-cell cancer therapeutic.
Patent CA-3036193-A1 (CA)
Inventor: Nagpal Varun
IPC: G08G1/056
Filed: 2017-08-29
Abstract: An turn detection system is configured to determine headings or a course of a vehicle over a period of time and evaluate whether the vehicle has registered a turn based on these headings/course. In some arrangements, upon detecting a turn, sensor data may be collected to determine one or more characteristics or attributes of the turn. Such data may indicate a loss event associated with the turn and be used to calculate a probability or risk of loss given the various characteristics of the turn. These probabilities may further be applied to determine various costs and premiums.
Patent CA-3036996-A1 (CA)
Title: Fluid catalytic cracking process and apparatus for maximizing light olefin yield and other applications
Inventor: CHEN LIANG
IPC: B01J8/26
Filed: 2017-09-14
Abstract: Apparatus and processes herein provide for converting hydrocarbon feeds to light olefins and other hydrocarbons. The processes and apparatus include, in some embodiments, feeding a hydrocarbon, a first catalyst and a second catalyst to a reactor, wherein the first catalyst has a smaller average particle size and is less dense than the second catalyst. A first portion of the second catalyst may be recovered as a bottoms product from the reactor, and a cracked hydrocarbon effluent, a second portion of the second catalyst, and the first catalyst may be recovered as an overhead product from the reactor. The second portion of the second catalyst may be separated from the overhead product, providing a first stream comprising the first catalyst and the hydrocarbon effluent and a second stream comprising the separated second catalyst, allowing return of the separated second catalyst in the second stream to the reactor.
Patent CA-3037267-A1 (CA)
Title: Device for monitoring the use of blister packaged contents at a distance
Inventor: WILSON ALLAN
IPC: A61J1/03
Filed: 2019-03-20
Abstract: There is provided a device for monitoring the use of a blister package, strip package, vial or bottle contents at a distance. A processor is connected to a compact random or quasi-random n-microphone array and is programmed to detect the sound of the content being expelled from a blister cavity, strip package, or a cap being removed from a vial or bottle.  A content use data memory associated with the processor stores information relating to the expulsion or removal events. The processor is equipped with statistical means for differentiating the sound of the content being expelled, from the background noise, generating an electrical signal that is analyzed for relevance to content use events by the processor, and storing the resulting use data in memory. The processor may have an adaptive beam focussing algorithm to determine the direction of the source of the sound.
Patent CA-3037595-A1 (CA)
Inventor: BAHMANYAR MOHAMMAD REZA
IPC: A61B5/0215
Filed: 2017-09-20
Abstract: An implantable device for deployment inside a human or animal body, the device comprising at least one sensing component arranged to respond to an electrical signal having a known frequency band and at least one antenna comprising at least one antenna pole connected to the at least one sensing component, the antenna pole comprising at least one helical coil and a connecting stem.