Patent SG-11201811339S-A (SG)
Title: Sensors having integrated protection circuitry
Inventor: FUNG TRACY HELEN
IPC: G01N21/78
Filed: 2018-04-19
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111101111 0 1110101011111 011101 0 01111111111111111111111111111111111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2018/200300 Al 01 November 2018 (01.11.2018) WI PO I PCT (51) International Patent Classification: ANOV, Boyan; 5200 Illumina Way, San Diego, California GO1N 21/78 (2006.01) GO1N 35/00 (2006.01) 92122 (US). GO1N 21/77 (2006.01) (74) Agent: DIERKER, Julia Church et al.; Dierker & Ka- (21) International Application Number: vanaugh, P.C., 3331 W. Big Beaver Road, Suite 109, Troy, PCT/US2018/028265 Michigan 48084 (US). (22) International Filing Date: (81) Designated States (unless otherwise indicated, for every 19 April 2018 (19.04.2018) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (25) Filing Language: English CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (26) Publication Language: English DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (30) Priority Data: HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, 62/489,840 25 April 2017 (25.04.2017) US 19043 09 June 2017 (09.06.2017) NL KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, N20 OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (71) Applicant: ILLUMINA, INC. [US/US]; 5200 Illumina SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, Way, San Diego, California 92122 (US). TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (72) Inventors: FUNG, Tracy Helen; 5200 Illumina Way, San (84) Designated States (unless otherwise indicated, for every Diego, California 92122 (US). CAI, Xiuyu; 5200 Illumi- kind of regional protection available): ARIPO (BW, GH, _ na Way, San Diego, California 92122 (US). KWOK, Lisa; GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, 5200 Illumina Way, San Diego, California 92122 (US). UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, = TRAN, Hai; 5200 Illumina Way, San Diego, California TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, 92122 (US). SAMIEE, Kevan; 5200 Illumina Way, San EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, =_ Diego, California 92122 (US). QIANG, Liangliang; 5200 MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, Illumina Way, San Diego, California 92122 (US). BOY- = (54) Title: SENSORS HAVING INTEGRATED PROTECTION CIRCUITRY (57) : An example sensor includes a flow cell, a detection 1 • device, and a controller. The flow cell includes a passivation layer = having opposed surfaces and a reaction site at a first of the opposed = 3C surfaces. The flow cell also includes a lid operatively connected to = the layer to define a flow channel between the passivation partially 1 = 12 = 44 22 32 104 lid and the reaction site. The detection device is in contact with a second of the opposed surfaces of the passivation layer, and includes _ am 24 an embedded metal layer that is electrically isolated from other de- tection circuitry of the detection device. The is to IF AI .41:- controller ground = = W the embedded metal layer. = 0. : 72 _ = — = 1 ' •‘'• , • , . , , ' ma .04 0 • ------------------ ' 14\" „ , ommomi — WI 74 Il RIPI TM .4 en War Are 0 0 D18 1 - -- 104' N--, ---.... RErERENCE Il FIG. 12 GND © ei C [Continued on next page] WO 2018/200300 Al MIDEDIMOMOIDEIRDERIO 010 I HI I IHMEMOIS TR), OAPI (BF, BJ, CF, CG, CM, GA, GN, CI, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — as to the identity of the inventor (Rule 4.17(0) Published: — with international search report (Art. 21(3))