baber/WOPTO huggingface dataset:
Patent PT-2159230-E (PT)
Title: Anti-tnf antibodies, compositions, methods and uses
IPC: A61K39/00
Filed: 2001-08-07
Abstract: The present invention relates to at least one novel anti-TNF antibody, including isolated nucleic acids that encode at least one anti-TNF antibody, TNF, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
Patent PT-2496291-E (PT)
Title: Protective syringe sleeve
Inventor: BEEBE SCOTT W
IPC: A61M5/315
Filed: 2010-11-02
Abstract: A protective sleeve placed within the cylinder of a syringe, the sleeve protects a piston and a computer controlled device or human operator pushing the piston from material leaking past a piston assembly. The sleeve has lips or ridges at either end, one that is attached to the piston assembly at the output end of the syringe and a second lip that is attached with a retention plate at the far end of the syringe. The sleeve may have a bellows or accordion configuration that slides along the inner surface of the syringe cylinder without appreciably loading the drive mechanism.
Patent PT-619730-E (PT)
Inventor: ALAKHOV VALERY Y
IPC: A61P35/00
Filed: 1993-10-08
Abstract: Compositions of anti-neoplastic agents incorporate the agent in micelles of at least one block copolymer of poly(oxyethylene)-poly(oxypropylene) in which the ratio of (oxypropylene) blocks to the (oxyethylene) blocks is from about 0.25 to about 1.5 and the micelles have an average diameter of from about 10 to about 25 nm.
Patent PT-670104-E (PT)
Inventor: SCHIPPER JOB
IPC: A01F25/00
Filed: 1995-02-27
Abstract: A method of treating primed seeds which results in a prolongation of shelf life compared to optionally dried conventionally primed seeds of the same species having substantially the same moisture content (MC), wherein the primed seeds are subjected to a water stress, a heat treatment or a combination thereof and are subsequently-where desired- dried back to a desired MC and seeds obtainable by such a method.
Patent PT-800408-E (PT)
Inventor: PREVOST ANDRE
IPC: C11D1/22
Filed: 1995-12-29
Abstract: Disclosed herein is a synergistic cleaning and disinfecting composition for use in decontaminating biofilm-coated surfaces like fresh water lines providing water supply to dental instruments, these lines being susceptible to contamination by microorganisms and being susceptible to the formation of biofilm coatings on their inner walls, the composition comprising an effective amount of a detergent, an effective amount of a denaturing agent attacking the extracellular matrix formed between microorganisms and between microorganisms and the inner walls of these water lines and an effective amount of a bactericide for destroying the microorganisms.
Patent PT-840603-E (PT)
Inventor: LEVY RUTH
IPC: A61K9/20
Filed: 1996-07-18
Abstract: The present invention provides a pharmaceutical composition contains a therapeutically effective amount of L-DOPA ethyl ester and a carrier which comprises from 5.5 to 98.5% hydroxypropylmethyl cellulose, from 0.25 to 4.5% hydroxypropyl cellulose, and from 1 to 90% of a carboxyvinyl polymer.
Patent PT-861231-E (PT)
Inventor: HALLINAN E ANN
IPC: A61K31/155
Filed: 1996-09-09
Abstract: There is disclosed a novel amino alcohol amine derivatives of L-N6-(1-iminoethyl)lysine, pharmaceutical compositions containing these novel compounds, and to their use in therapy, in particular their use as nitric oxide synthase inhibitors.
Patent PT-866791-E (PT)
Inventor: MASCIADRI RAFFAELLO
IPC: C07D239/49
Filed: 1996-11-22
Abstract: Diaminopyrimidines of general formula I <CHEM>  wherein   R<1>   signifies hydrogen, R<2>   signifies C3-5- omega -carboxyalkyl; R<3>   signifies C1-5-alkyl; and their pharmaceutically acceptable acid addition salts have antibiotic properties and can be used in the control or prevention of infectious diseases.
Patent PT-888325-E (PT)
Inventor: BRYANS JUSTIN S
IPC: A61P25/06
Filed: 1997-01-02
Abstract: PCT No. PCT/US97/00255 Sec. 371 Date May 18, 1998 Sec. 102(e) Date May 18, 1998 PCT Filed Jan. 2, 1997 PCT Pub. No. WO97/29101 PCT Pub. Date Aug. 14, 1997Novel cyclic amino acids of formula (Ia) or (Ib) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, and neuropathological disorders. Processes for the preparation and intermediates useful in the preparation are also disclosed:
Patent PT-1002022-E (PT)
Inventor: SCHUMANN WERNER
IPC: C09B67/42
Filed: 1998-07-20
Abstract: Granular compacts (G) of a mixture of(A) at least one water-soluble dye or optical brightener, and(B) extender and, optionally,(C) at least one hydrophilic surfactant and/or(D) further additives, additionally containing(E) a dust-binding oil,are low-dust dry formulations of high bulk density which feature good dissolution, transportation and storage properties and are outstandingly suitable for the dyeing of the respective substrates.
Patent PT-1001929-E (PT)
Inventor: MARHOLD ALBRECHT
IPC: C07C253/30
Filed: 1998-07-18
Abstract: The present invention relates to a process for preparing 3-cyano-2,4-dihalogeno-5-fluoro-benzoic acid, to intermediates for carrying out the process and to processes for preparing these intermediates.
Patent PT-1062244-E (PT)
Inventor: KELLEY BRIAN D
IPC: C12N15/09
Filed: 1999-03-11
Abstract: Methods are provided for purification of Factor VIII polypeptides by immunoaffinity chromatography and ion exchange chromatography, in which the eluate from the immunoaffinity column is diluted with a solution comprising higher salt concentration, or lower non-polar agent concentration than that of the elution solution, prior to passing the diluted solution through the ion exchange column. The methods result in improved purification without significant yield loss.
Patent PT-1115512-E (PT)
Title: Chemical oxidation of volatile organic compounds
Inventor: WOODY BERNARD A
IPC: B09C1/02
Filed: 1999-05-04
Abstract: Volatile organic compounds are removed from contaminated soil by introducing one or both a water soluble peroxygen compound, such as a persulfate, and a permanganate into the soil, either in situ or ex situ, in amounts and under conditions wherein both the soil oxidant demand is satisfied and volatile organic compounds in the soil are oxidized. In a preferred embodiment, when both are used the peroxygen satisfies the soil oxidant demand and the permanganate oxidizes the volatile organic compounds. Sodium persulfate is the preferred persulfate and potassium permanganate is the preferred permanganate. The persulfate and the permanganate may be added to the soil sequentially, or may be mixed together and added as an aqueous solution.
Patent SG-7186-G (SG)
Title: Hybrid cell line for producing monoclonal antibody to a human monocyte antigen, antibody, and methods
IPC: G01N33/50
Filed: 1986-01-23
Abstract: Hybrid cell line for production of monoclonal antibody to an antigen found on normal human monocytes and granulocytes. The hybrid is formed by fusing splenocytes from immunized BALB/cJ mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
Patent SG-82692-G (SG)
Title: Injection moulding or press tool for working plastic materials
IPC: B29C33/42
Filed: 1992-08-18
Abstract: A die for processing a pliable plastic moldable material, particularly a plastic resin, has a cylindrical circular cross sectioned passage provided in the die wall. A marking device for the die comprises a ring body held space-fixed in the cylindrical circular cross sectioned passage of the die and a cylindrical circular cross sectioned central body received rotatable, coaxial, and stepwise lockable in the ring body. Both the front surface of the central body and the ring shaped front surface of the ring body form part of the embossing surfaces of the die. The rotatable front surface of the central body carries an indicating mark, while the space-fixed ring shaped front surface of the ring body adjoining the rotatable front surface of the central body is provided with a number of other marks, which can give the date or dates. The marking device can advantageously be constructed as a standardized part and is easily mounted in the die, without which the embossing die must be provided with additional marks on its embossing surfaces. For a case in which the marking assembly must be changed due to for example a date change, the central body is conveniently adjustable by a tool from the die space.
Patent IE-43076-L (IE)
Title: Conveyor apparatus for use in proofing dough
IPC: A21C13/02
Filed: 1976-01-15
Abstract: A dough proofing apparatus is for use in association with a dough forming apparatus having a dough piece receiving means which receives preformed dough pieces from a dough dividing machine and directs them toward a toroid forming apparatus wherein the proofing apparatus includes dough conveyance means for receiving and conveying dough pieces in a proofing mode of travel through a closed loop path of travel of the conveyor belt between generally adjacent dough entry and dough exit locations on the toroid forming apparatus. The conveyance belt is passed over vertically spaced pulleys with dough pieces retained thereon by adjacent dough support means on the conveyance belt which cooperate to form open-ended cage-like dough retaining receptacles for dough pieces as they travel on the conveyance means over and about the vertically spaced pulleys. In an alternative embodiment thereof, the conveyance means has its vertically spaced pulleys mounted on axes at various angles to one another in order to provide a change in axis of rotation for the conveyance belt of 180 DEG as it goes about the closed loop path of travel to reverse the inner and outer sides of the conveyance belt once per complete revolution. Alternative forms of dough receptacles are also disclosed.
[US3986446A]
Patent IE-32692-L (IE)
Title: Crossbar switch
IPC: H01H67/26
Filed: 1968-04-01
Abstract: 1,157,768. Cross-bar switch. 
INTERNATIONAL STANDARD ELECTRIC CORP. 21 March, 1968 [21 April, 1967], No. 13709/68. 
Addition to 1,124,932. 
Heading H1L. 
A cross-bar switch comprises a base-plate formed by a printed circuit board 1, Fig. 1, on which a number of resilient contact elements 5 are mounted, two rows only being shown, each contact element being anchored at one end to the board in electrical contact with a circuit on the board. 
The base is fixed to the lower surface of a frame 8 which accurately locates the lower ends of the contact elements and which carries on its upper surface the select and connect bars 12 and 13, only two of each being shown, which are movable by operation of the electromagnetic actuators 27 and 28. 
Mounted over the top of frame 8 is a contact support plate 38, the top surface of which is grooved, as at 41, to take stationary contact elements 40 in the form of springs, as described in Specification 1,100,875, which are held in place by ribs 44 on lid 39 which engage transverse grooves 98 in the support plate 38 and apply retaining pressure on the springs 40. 
The bottom surface of the support plate is grooved to provide an L-shaped guiding path for the free ends of the contact elements 5 between a position in which the elements 5 are out of contact with the fixed contact springs 40 and a position where they engage between adjacent turns of the spring. 
The select and connect bars are each resiliently biased in a direction away from the actuators 27 and 28 by spring- loaded tongue members in the walls 19 and 20 of the frame 8 and are displaced in the other direction when the actuators are energized. 
Each select bar 12 has a number of rectangular apertures through which respective movable contact elements pass and each connect bar has a number of rectangular apertures each having a tooth projecting into the interior thereof. 
Switch operation.-Normally, the movable contact elements, e.g. 57 and 58, Fig. 4, which shows only the active portions of the apertures in the select and connect bars, are biased by their own resilience into one corner of the bar apertures. 
To select a cross-point the connect bar is operated to the position shown in Fig. 5 then the select bar is operated as at 51 in Fig. 7, the connect bar is released, the tooth 56 carrying the movable contact to engage the fixed contact 59 and finally the select contact is released leaving the selected movable contact 58 still held, by the restoring spring action on the connect bar, in contact between adjacent turns of the fixed contact spring 59. 
To release the connection the connect bar is operated once again when the movable contact returns, by its own resilience, to its original position. 
(From GB1157768 A) 
[FR1527209A]
Patent IE-32710-L (IE)
Title: Retail display of razor blade dispensers
IPC: G09F23/06
Filed: 1969-03-31
Abstract: 1,235,205. Packaging. W I L K I N S O N SWORD Ltd. 21 March, 1969 [13 Nov., 1968], No. 53809/68. Heading B8C. [Also in Division A4] A display and packaging device comprises a mounting sheet 10, e.g. a card, to which a number of cards 13 carrying, e.g. a bubble package 15 of a razor blade dispenser 14 are detachably secured by tabs 12 integrally formed in the sheet entering bubble package card openings 13a, the spacing of the bubble cards being such that at most any one card does not overlap more than a part of another card.
[GB1235205A]
Patent IE-41533-L (IE)
Title: Thiomethyl ergolene derivatives
IPC: C07D407/02
Filed: 1975-02-12
Abstract: 1497681 6 - Methyl - 8 - mercaptomethylergolenes and ergolines SANDOZ Ltd 10 March 1975 [14 March 1974 23 July 1974] 9807/75 Heading C2 [Also in Division A5] Novel compounds of the Formula I wherein # is the group -CH = CH or and R is hydrogen; cyano; a 5- or 6-membered unsaturated heterocyclic radical attached through a ring carbon atom and having 1 to 3 heteroatoms, the first hetero atom being introgen, oxygen-or sulphur-and the second and third heteroatoms, if present, being nitrogen; or a 2- or 4-pyridyl monosubstituted by C 1-4 alkyl or alkoxy or chlorine, fluorine or bromine, with the proviso that when # is -CH=C< and the side chain in the 8 position has the #- configuration then R is other than 2-pyridyl, and acid addition salts thereof, may be prepared by reacting a compound of Formula II wherein X is a radical capable of being displaced by a thio group with a compound of the formula M5R wherein M is hydrogen or alkali metal or by reducing the -SCN group in a compound of the Formula I in which R is CN to -5N. 6 - Methyl - 8α - methanesulphonyloxymethyl ergoline-I is prepared by acrylation of 9,10- dihydro-isolysergol I with methane sulphonyl chloride. The compound I excluded by the proviso is the subject of Divisional Specification 1,497,682.
Patent IE-39349-L (IE)
Title: Remote control system for a stockpiling machine
IPC: B65G43/00
Filed: 1974-03-25
Abstract: 1459433 Automatic control POWERSCREEN INTERNATIONAL Ltd 27 March 1974 [30 March 1973] 15502/73 Heading G3N A remote control system for a stockpiling machine comprises a power supply, a transmitter 1, a receiver 2, and a decoder unit 3 which operates solenoid valves 5 through electronic switches 4. Transmitter 1 is crystal controlled and uses pulse sequence modulation or is a dual frequency transmitter. The receiver 2 has automatic gain control and is powered from a supply 30 comprising an alternator 31 a battery 32 and a voltage control unit 33. Decoder unit 3 includes a trigger detector circuit to prevent an intermediate signal state and a lock-out circuit to prevent simultaneous energization of more than one solenoid. A local control may be mounted on the stock-piling machine, the control being rendered operational by switch 6.
[GB1459433A]
Patent IE-790668-L (IE)
Title: Dressing glass fibres.
IPC: C03C25/26
Filed: 1979-08-08
Abstract: Sizing compositions comprising a combination of several adhesive agents capable of being cross-linked, an acrylic polymer and a coupling agent, are used to treat glass fibers in order to provide improved plastic reinforcing fibers especially suited to use in sheet molding compounds whereby molded articles, particularly large pieces formed therefrom, will have improved reinforcement and surface characteristics.[EP0004816A3]
Patent IE-780811-L (IE)
Title: Vaccine against newcastle disease
IPC: A61K39/17
Filed: 1978-04-24
Abstract: The invention relates to an avian vaccine and to the preparation thereof. The vaccine according to the invention is a Newcastle disease virus vaccine. Its active ingredient is the P/77/8 NDV strain. The vaccine of the invention is useful in the prevention of Newcastle disease by administration to chickens in the form of an aerosol.
[US4235876A]
Patent IE-870843-L (IE)
Title: Composition of fr-900506.
IPC: A61K31/395
Filed: 1987-04-01
Abstract: A solid dispersion composition comprising 17-allyl-1,14-dihydroxy-12-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methyl vinyl [23,25-dimethoxy-13, 19,21, 27-tetramethyl-11,28-dioxa-4-azatricyclo [22.3.1.0<4,9>] octacos-18-ene-2,3,10,16-tetraone and a water-soluble polymer, and processes for preparing such solid dispersion composition.
[EP0240773A1]
Patent IE-32228-L (IE)
Title: Diamond compacts
IPC: B01J3/06
Filed: 1968-07-29
Abstract: 1,240,526. Diamond compacts. GENERAL ELECTRIC CO. 1 Aug., 1968 [8 Sept., 1967], No. 36802/68. Heading C1A. A high strength coherent polycrystalline diamond compact consists essentially of a plurality of boron-doped diamond particles which particles contain at least 0.01% by weight boron; said compact containing no more than 2% by weight of a material other than diamond, such material if any being boron, tantalum, molybdenum, titanium and carbides of these elements; said compact having a density in excess of 91% of the theoretical density of single crystal diamond. The diamond particles are preferably less than 20 microns. The compacts may be produced by compacting the boron doped diamond particles with or without the additive material either as a matrix or coating on the diamond particles at a pressure in excess of 50 kilobars and a temp. in excess of 1300 C. to form the desired high strength coherent compact. The compacting step may be performed in a reducing environment.
[GB1240526A]
Patent IE-820924-L (IE)
Title: Sulfonic acid halides and amides.
IPC: C07C309/87
Filed: 1982-04-20
Abstract: The invention relates to trisubstituted sulfohalides, the process for their preparation and their use as intermediate products for the manufacture of novel compounds. The trisubstituted sulfohalides according to the invention correspond to the following general formula (I):    <IMAGE>  (I)  in which: X is a halogen atom, particularly bromine or preferably chlorine; R3 and R4 each represent, independently of one another, a lower alkyl radical having from 1 to 4 carbon atoms, A represents hydrogen, halogen, alkoxy radicals having from 1 to 4 carbon atoms, alkylsulfonyl groups having from 1 to 4 carbon atoms, or the group NO2, or CF3. The invention is useful in the manufacture of medicaments.
Patent IE-810928-L (IE)
Title: 1-(acylamino-aryloxy)-3-alkylamino-propan-2-ols sulfonamides.
IPC: C07C253/00
Filed: 1981-04-24
Abstract: This invention relates to compounds of the formula    <IMAGE>  (I) wherein R1 represents a linear or branched alkyl of from 1 to 20 carbon atoms; R2 represents a hydrogen or halogen atom, a linear or branched alkyl or alkoxy of from 1 to 4 carbon atoms, or a divalent group -CH=CH-CH=CH- or -(CH2)n-, in which n is an integer of from 3 to 5, with the free valences bonded in the o-position relative to one another; and R3 represents a linear or branched alkyl of from 3 to 10 carbon atoms, with the provisos that R3 is not tert.butyl when R1 is ethyl or propyl and R2 is a hydrogen atom and that R3 is not isopropyl when R1 is propyl and R2 is a hydrogen atom, or a non-toxic, pharmacologically acceptable acid addition salt thereof. The compounds of Formula I are useful for treatment and prophylaxis of diseases of the coronaries, for the treatment of hypertension, and for treatment of cardiac arrhythmia, particularly tachycardia.
Patent IE-780937-L (IE)
Title: Determination of sub-surface formation properties
IPC: E21B49/00
Filed: 1978-05-09
Abstract: The disclosure is directed to an apparatus and method for determining the water-filled porosity of formations surrounding a borehole. Alternatively, where porosity is known from other logging information, the disclosed techniques can be utilized for determining the conductivity of the water in formations surrounding a borehole or for determining water saturation. The formations are assumed to comprise a matrix, which may be any subsurface solid material, and fluids contained in the matrix, such as in pore spaces or interstices therein. In accordance with one embodiment, means are provided for deriving a first quantity which is representative of the attenuation of microwave electromagnetic energy propagating between spaced locations in the borehole, the first quantity being, for example, the attenuation constant, alpha . Means are also provided for deriving a second quantity representative of the relative phase shift of microwave electromagnetic energy propagating between the spaced locations, the second quantity being, for example, the phase constant, beta . Further means are provided for deriving a third quantity representative of the conductivity of the water in the formations surrounding the spaced locations. In the preferred form of the invention, the investigated formations are in the invaded zone surrounding the borehole and the conductivity of the water is determinable from the conductivity of the drilling mud being utilized and the nature of the mud filtrate resulting from invasion of the formations by the drilling mud. Means are also provided for generating a fourth quantity which is proportional to the product of the first and second quantities and inversely proportional to the third quantity. The generated fourth quantity is indicative of the water-filled porosity, phi w, of the formations adjacent the region of the spaced locations in the borehole. In alternative forms of the invention, where porosity is known, the conductivity, sigma w, or the apparent conductivity, sigma w', of the water in formations surrounding the borehole is determined.
[US4158165A]
Patent IE-810956-L (IE)
Title: 2-guanidinothiazole derivatives
IPC: A61K31/425
Filed: 1981-04-29
Abstract: Compounds of the general formula: <IMAGE> (wherein n is an integer from 2 to 4; R is hydrogen, C1-C6 alkyl (optionally substituted by hydroxy, cyano, amino or phenoxy), C3-C6 cycloalkyl, C2-C6 alkenyl (optionally substituted by phenyl or C2-C7 alkoxy-carbonyl), C4-C7 alkadienyl, C6-C12 aryl (optionally substituted by one to three groups selected from halogen, cyano, nitro, amino, C2-C10 dialkylamino, tetrazolyl, hydroxy, C1-C6 alkoxy, benzoyloxy, C2-C7 alkoxycarbonyl, sulfamoyl, C1-C6 alkylsulfonyl, C1-C6 alkanesulfonamido or C1-C6 alkanoyl), or a heterocycle (optionally substituted by halogen, C1-C6 alkyl or phenyl); and X is a single bond or thia), their 5-halo and alkyl derivatives and salts thereof are anti-peptic ulcer agents and histamine H2 receptor antagonists. The preparation of 1-chloro-3-[2- acetamidoethylthio)-2-propanone is described.
[GB2076397A]
Patent FI-812426-L (FI)
Inventor: GRIFFIN GERALD JOSEPH LOUIS
IPC: C08L3/02
Filed: 1981-08-05
Abstract: A starch/plastics composition has natural starch granules with surfaces modified to render them reactive with the plastics. Thus the starch granules may be reacted with sodium hydroxide prior to mixing with a polyester resin.