Patent SG-11201910019P-A (SG)
Title: Microorganisms and methods for producing cannabinoids and cannabinoid derivatives
Inventor: KEASLING JAY D
IPC: C12N15/52
Filed: 2018-04-27
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 01 November 2018 (01.11.2018) omits I E H 01010 MODE 011 (10) International Publication Number WO 2018/200888 Al WIPO I PCT (51) International Patent Classification: C12N 9/10 (2006.01) Cl 2P 7/22 (2006.01) C12N 15/52 (2006.01) Cl 2P 17/06 (2006.01) (21) International Application Number: PCT/US2018/029668 (22) International Filing Date: MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) W O 20 18/ 200888 Al 27 April 2018 (27.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/491,114 27 April 2017 (27.04.2017) US 62/569,532 07 October 2017 (07.10.2017) US (71) Applicant: REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, Oakland, California 94607 (US). (72) Inventors: KEASLING, Jay D.; 2150 Shattuck Ave., Suite 510, Berkeley, California 94704 (US). D'ESPAUX, Leo; 2150 Shattuck Ave., Suite 510, Berkeley, California 94704 (US). WANG, Jeff; 2150 Shattuck Ave., Suite 510, Berke- ley, California 94704 (US). LUO, Xiaozhou; 2150 Shat- tuck Ave., Suite 510, Berkeley, California 94704 (US). REITER, Michael; 2150 Shattuck Ave., Suite 510, Berke- ley, California 94704 (US). DENBY, Charles; 2150 Shat- tuck Ave., Suite 510, Berkeley, California 94704 (US). LECHNER, Anna; 2150 Shattuck Ave., Suite 510, Berke- ley, California 94704 (US). (74) Agent: OSMAN, Richard Aron; 530 Lawrence Expy #332, Sunnyvale, California 94085 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (54) Title: MICROORGANISMS AND METHODS FOR PRODUCING CANNABINOIDS AND CANNABINOID DERIVATIVES (57) : The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative.