baber/WOPTO huggingface dataset:
Patent JP-3127298-B2 (JP)
IPC: C07K14/315
Filed: 1990-07-31
Granted: 2001-01-22
Abstract: The present invention relates to the field of biotechnology and genetic engineering and in particular a novel nucleotide sequence which codes for a streptokinase, as well as the recombinant DNA obtained therefrom which is used for the transformation of various host organisms. The technical object which is pursued with the proposed solution is to produce the protein in commercially useful quantities, by the recombinant method, with the possibility of alternatively using different hosts to obtain a high-quality streptokinase capable of being used as a thrombolytic agent in the treatment of different disorders. The present invention is based on the isolation of a new gene which codes for streptokinase from Streptococcus equisimilis of type C (strain ATCC-9542) and the cloning and expression thereof in prokaryotic (E. coli) and eukaryotic (Pichia pastoris) hosts, for which it includes the vehicles of expression which contain the genetic sequences of said gene, as well as the microorganisms transformed with these vectors capable of producing streptokinase. The protein obtained thereby can be used in clinical medicine as a therapeutic agent, in the treatment of disorders such as thromboembolic obstructions including coronary thrombosis.
Patent JP-2801212-B2 (JP)
IPC: G01N33/68
Filed: 1988-08-18
Granted: 1998-09-21
Abstract: A trimeric aminoterminal propeptide of type III procollagen free of proteolytic activity that could degrade the propeptide may be used to produce an antibody specific to the trimeric propeptide and which has no affinity for the monomeric degraded propeptide. This antibody may be used to assay more accurately propeptide which is a measure of rate of production of collagen, which is useful in diagnosing e.g. fibrosis.
Patent JP-3324215-B2 (JP)
IPC: F01N11/00
Filed: 1993-08-30
Granted: 2002-09-17
Abstract: An air/fuel ratio sensor abnormality detecting device avoiding influence of degradation of O2 storage effect of a catalyst due to deterioration, includes linear air/fuel ratio sensors for linearly detecting the air/fuel ratio being employed as upstream side and downstream side air/fuel ratio sensors, delay period deriving means for deriving a gas response delay period between the both air/fuel ratio sensors on the basis of the results of detection of the upstream side and downstream side air/fuel ratio sensors while the air/fuel ratio feedback control is effected under lean condition of the air/fuel ratio, and abnormality detecting means for detecting abnormality of the downstream side air/fuel ratio sensor on the basis of the derived delay period. Since the gas response delay period is derived on the basis of the results of detection in the upstream and downstream side linear air/fuel ratio sensors in a air/fuel ratio lean range which is not influenced by the O2 storage effect, the derived delay period is not influenced by the deterioration condition of the catalyst so that the abnormality detection for the downstream side linear air/flow rate sensor can be done with high accuracy. By employing the linear air/fuel ratio sensors, stable lean condition can be realized.
Patent JP-3003400-B2 (JP)
IPC: H01G11/24
Filed: 1992-08-19
Granted: 2000-01-24
Abstract: PURPOSE:To obtain an electric double layer capacitor wherein its equivalent series resistance can be reduced easily without exerting a high pressure on an element. CONSTITUTION:Powdery activated carbon is mixed with a solution in which a phenol resin has been dissolved by 2-methoxyethanol, an activated carbon fiber is coated with this mixture, this assembly is heated and treated, and a polarizing electrode 1 is obtained. The polarizing electrode 1 is impregnated with an electrolytic solution, ft is then arranged in a recessed part formed by compression-bonding a ring-shaped gasket 4 and a conductive separator 2, and this pair is united via a porous separator 3, covulcanized and bonded. Thereby, it is possible to constitute an electric double layer capacitor whose equivalent series resistance is low and whose electrode is not cracked even when the polarizing electrode is made thin.
Patent JP-3828597-B2 (JP)
IPC: A61P9/06
Filed: 1995-09-08
Granted: 2006-10-04
Abstract: Benzoyl guanine derivs. of formula(I) and their salts are new. One of the substits. R1-R3 = Y-Ph-Ä(CH2)k-CHR7-CO-R8Ü; and the others = 1-8C alkyl, 2-8C alkenyl, (CH2)mR14, SO2NHC(=Y')NR18R19, H, halo, CN, Z(CH2)p-CqF2q+1, SOuR22, CONR23R24, COR25, SO2NR26R27, OR35 or NR35R36; Ph = phenylene (opt. mono- or di-substd. by Fl, Cl, CF3, Me, OH, OMe or NR37R38); R37, R38 = H or Me; Y = a bond, O, S or NR9; R9 = H or 1-4C alkyl; R7 = OR10 or NR10R11; R10 = H 1-8C alkyl, 1-8C alkanoyl, 1-8C alkoxycarbonyl, benzyl, or benzyloxycarbonyl; R11 = as R10 or trityl; R8 = OR12 or NR12R13; R12, R13 = H, 1-8C alkyl or benzyl; R14 = 3-8C cycloalkyl or phenyl (both opt. substd. by 1-3 F, Cl, CF3, Me, OMe, or NR15R16); R15, R16 = H or Me; Y' = O, S or NR20; R18, R19 = H, 1-8C alkyl, 3-6C alkenyl or (CH2)tR21; or R18+R19 = A; R21 = 5-7C cycloalkyl or phenyl, (both opt. mono- to tri-substd. by F, Cl, OMe or 1-4C alkyl); R20 = as R18 or amidine; Z = a bond, O, S or NR28; R22 = 1-8C alkyl, 3-6C alkenyl, (CH2)nR29 or CF3; R23, R25, R26 = as R22 or H; R24, R27 = H or 1-4C alkyl; or R23+R24, R26+R27 = A; A = (CH2)4 or (CH2)5 (both opt. having a CH2 replaced by O, S, NH, NMe or N-benzyl; R28 = H or 1-3C alkyl; R29 = 3-7C cycloalkyl or phenyl (both opt. substd. by 1-3 F, Cl, CF3, Me, OMe or NR30R31; R30, R31 = H or 1-4C alkyl; R35, R36 = H or 1-6C alkyl; or R35+R36 = (CH2)y (opt. having a CH2 gp. replaced by O, S, NH, NMe or N-benzyl); R4, R5 = H, 1-4C alkyl, F, Cl, OR32, NR33R34 or CrF2r+1; R32-R34 = H or 1-3C alkyl; k, n, t = 0-4; m, u, p = 0-2; q = 1-6; r = 1-4; and y = 4-7.
Patent JP-H0375521-B2 (JP)
IPC: A01N25/04
Filed: 1982-12-23
Abstract: Oil-in-water dispersions containing polyvinyl alcohol, surfactant and a salt with improved freeze-thaw and elevated temperature storage stability.
Patent JP-H0672113-B2 (JP)
IPC: C07C31/125
Filed: 1990-09-21
Abstract: The present invention relates to a process for the preparation of alcohols by reacting organic carbonyl compounds with hydrogen at increased temperature and optionally increased pressure, in two steps, where, in the first step, the gaseous carbonyl compounds are passed to a copper-containing catalyst and, in the second step, the liquid carbonyl compounds are passed to a nickel-containing catalyst. The carbonyl compounds are reacted in the first step to an extent of 80 to 99.5% of theory and in the second step by means of a support catalyst which contains nickel, aluminium oxide and zirconium dioxide. The carbonyl compounds used are aldehydes and their derivatives, in particular aliphatic unsaturated and saturated aldehydes.
Patent JP-H0588834-B2 (JP)
IPC: H01L21/027
Filed: 1985-11-22
Abstract: Disclosed is a radiation-sensitive composition, a recording material prepared therewith, and process therefor. The invention is suitable for the production of printing plates and photoresists. The composition contains a 1,2-quinonediazide or a combination of (1) a compound which, under the action of actinic radiation, forms a strong acid, and (2) a compound which possesses at least one acid-cleavable C-O-C bond, the solubility of which in a liquid developer is increased by the action of acid and, as the binder, a polymer having lateral crosslinking groups of the formula -CH2OR, in which R is a hydrogen atom, a lower alkyl group, acyl group or hydroxyalkyl group. After being exposed and developed, the composition can be thermally cured and results in an image stencil exhibiting a clean background.
Patent JP-H06104058-B2 (JP)
IPC: A61K35/66
Filed: 1988-10-21
Abstract: Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.
Patent JP-3097890-B2 (JP)
IPC: B24D3/28
Filed: 1993-11-09
Granted: 2000-10-10
Abstract: The invention describes a polyurethane having a softening temperature above 65 DEG C and being formed by the reaction, in the presence of a curing agent, of an isocyanate-terminated polymer with an hydroxyl-containing organic compound in proportions to provide a -NCO/-OH ratio of at least 1.5 to yield a crosslinked polyurethane comprising isocyanurate and/or oxazolidone structures. This polyurethane may be used as a binder, e.g. for composite abrasive wheels with improved thermal properties. Such an abrasive wheel is comprised of a fibrous substrate with abrasive particles adhered thereto by a crosslinked polyurethane binder comprising heterocyclic groups. The heterocyclic structures, such as isocyanurate and/or oxazolidone rings, in the binder system improve the thermal properties required for a tough, durable abrasive wheel.
Patent JP-S6310174-B2 (JP)
IPC: C04B35/56
Filed: 1986-11-27
Abstract: In a first stage, the aminolysis of a dichlorosilane and/or of a dichlorodisilane is carried out and the amine chloride formed is removed and, in a second stage, the aminolysate obtained during the first stage is reacted with at least one organosilicon compound chosen from an organochlorosilane, an organochlorodisilane, an organochloropolysilazane and an organochloropolydisilylsilazane containing at least three chlorine atoms per molecule, in the presence of a tertiary amine. A cationic polymerisation may be advantageously optionally carried out on the aminolysate obtained in the first stage. The polysilazanes thus treated exhibit a high heat resistance and can be employed especially as precursors of ceramic products, with a high yield of mineral product.
Patent JP-3570829-B2 (JP)
IPC: A61K8/00
Filed: 1996-10-24
Granted: 2004-09-29
Abstract: New composition (I) comprises a polymeric system (II) comprising an aqueous dispersion of particles of a film-forming polymer (III). (I) can be used for application to the skin or mucous membranes, particularly the lips, as make-up, protection and/or a non-therapeutic or therapeutic treatment. Also claimed is a lipstick containing (I).
Patent JP-3015867-B2 (JP)
IPC: A21C7/00
Filed: 1996-11-29
Granted: 2000-03-06
Abstract: Apparatus for dividing a long dough mass (200) into dough portions (210) of a predetermined length, and forming a continuous dough strip from the respective dough portions. A first transporter (20) transports the long dough mass (200) along a first conveying path (21). The first transporter includes a rotary cutter (31) for dividing the long dough mass into dough portions. A second transporter (40) receives the dough portions from the first transporter and transports them along a second conveying path (41). The first and second conveying paths are arranged so that the lengths of the dough portions extend substantially parallel to the width of the said continuous strip. A joining device (50) receives the dough portions and joins them to form the continuous dough strip. <IMAGE>
Patent JP-3719749-B2 (JP)
IPC: C08F214/26
Filed: 1995-12-28
Granted: 2005-11-24
Abstract: Tetrafluoroethylene (TFE) thermoprocessable copolymers comprising:       (A) from 0.1 to 15% by moles of a fluorodioxol of formula: <CHEM> wherein RF is a perfluoroalkyl having from 1 to 5 carbon atoms; X1 and X2, equal to or different from each other, are -F or -CF3; Z is selected from -F, -H, -Cl. (B) from 0 to 12% by moles of a perfluorinated monomer selected from hexafluoropropene (HFP) and perfluoropropylvinylether (PPVE), or their mixtures;   (C) TFE forming the remaining part to 100%; with the proviso that the total amount of the monomers (A) and (B) is lower than or equal to 20% by moles.
Patent JP-2857495-B2 (JP)
IPC: G01B11/06
Filed: 1990-12-20
Granted: 1999-02-17
Abstract: The present invention concerns a procedure for measuring the dimensions of a spacer consisting in: 
 
  - forming, on a substrate (1), an array of parallel strips (2) having a rectangular cross-section; 
  - producing spacers (7) on the lateral edges (6) of the parallel strips (2); 
  - illuminating the array with a light beam in order to produce a diffraction pattern whose envelope has a primary lobe and secondary lobes; 
  - measuring the sum of the light intensities of a predetermined number of spots belonging to the first secondary lobe; and 
  - and deriving from this the width  l  and the angle  THETA  of the spacer (7) by the following formulae:
  l  = k1 x IL1 + k2
  THETA  = k3 x IL1 + k4 
 
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Patent JP-3245418-B2 (JP)
IPC: C07D207/263
Filed: 1991-11-28
Granted: 2002-01-15
Abstract: 5-Substituted trans-1-piperazinoindan derivatives having general formula (I), wherein X is halogen, trifluoromethyl, alkyl, alkylthio, alkyloxy, hydroxy, alkylsulphonyl, alkyl- or dialkylamino, trifluoromethylthio or cyano; R is hydrogen, or alkyl, alkenyl, cycloalkyl, or cycloalkyl lower alkyl, optionally substituted with hydroxy, or R is a substituent (a), wherein n is an integer from 1 to 6; U is CH or N; Y is CH2, O, S or N-R<1>, R<1> being hydrogen or cycloalkyl, cycloalkylmethyl, alkyl or alkenyl optionally substituted with hydroxy or an optionally substituted phenyl group; W is O or S; Z is -(CH2)4-, (b), (c), where R<2> and R<3> are hydrogen or lower alkyl, -CH=CH-, -CH=CH-CH2-, optionally substituted 1,2-phenylene, 1,2-C6H4CH2- (to form a quinazolidinone or -thione ring system) or 1,2-C6H4CO- (to form a quinazolidindion or thioxoquinazolidinon ring system); and Ar is an optionally substituted phenyl, thiophene or furane ring; are selective, centrally acting 5-HT2 antagonists useful in the treatment of anxiety, depression, sleeping disorders, negative symptoms of schizophrenia and migraine.
Patent JP-H0535766-B2 (JP)
IPC: F16B12/20
Filed: 1987-02-13
Abstract: A fitting for the connection of construction elements, such as wooden construction elements. The fitting is made of two identical fish-belly shaped fitting components which insert into corresponding grooves in the construction elements. Each fitting element has harpoon-like webs to engage the construction elements. Opposite to the fish-belly portion of the fitting element is a blade and upon the blade is at least two hook heads spaced apart by at least the width of one hook head. In the connected position, the fitting components face each other and the two complementary fitting components grip one behind the other at the hook heads.
Patent JP-H0552751-B2 (JP)
Inventor: OLIVER ROY FREDERICK
IPC: A61L27/00
Filed: 1985-05-24
Abstract: A collagenous tissue preparation suitable for homotransplantation or heterotransplantion. The preparation is a non-resorbable, non-antigenic collagenous material which retains the natural structure and original architecture of the natural tissue. The material is substantially free of non-fibrous tissue proteins, glycoproteins, cellular elements and lipids. The tissue preparation is recolonized by host cells and revascularized after implantation into the host.
Patent JP-H0666949-B2 (JP)
IPC: H04N7/169
Filed: 1986-04-17
Abstract: A method and apparatus for creating a television signal and encrypting or decrypting the signal at the same time. Luminance and chrominance information are received by the apparatus and stored in separate television scan line stores. The stored liminance and chrominance information is read out from their respective stores at a frequency corresponding to a desired format or standard to create the television signal. The signal may be simultaneously encrypted or decrypted by delaying the time at which the luminance and/or chrominance information is read out in accordance with an encryption or decryption key.
Patent JP-3439762-B2 (JP)
IPC: G01N35/00
Filed: 1992-08-04
Granted: 2003-08-25
Abstract: A system which performs a plurality of independent analysis procedures simultaneously, possibly involving differing types of tissues and differing process steps, comprising a robotic device, which may cause the different tissue samples to be processed by processing stations, and a processor, which may select the next process step. The processor may direct the robotic device to interleave the differing process steps. The processor may select a next process step in response to timing information about the procedures, which may specify the start time and end time of each process step. The specified times may be exact or may be a range of times. The processor may determine the exact time for a step by generating a possible sequence of steps and examining that sequence for conflicts, adjusting that sequence in response to those steps with a specified range of times, and iterating the calculation over a plurality of possible sequences. The processor may also optimize the order in which process steps are performed to minimize the total time required by the system to complete the procedures, for example by generating a plurality of possible sequences, evaluating each sequence for total expected time, and selecting the best sequence available.
Patent JP-3481617-B2 (JP)
IPC: B01J20/32
Filed: 1992-08-07
Granted: 2003-12-22
Abstract: A method for the removal and concentration of desired ions such as Pd(II), Pt(IV), Pt(II), Pd(IV), Ru(III), Ru(II), Au(III), Os(IV), Au(I), Cu(I), Cu(II), Ag(I), and Hg(II) from a multiple ion source solution which may contain larger concentrations of other undesired ions including H+comprises bringing the source solution into contact with a compound comprising a thiol and/or thioether aralkyl nitrogen-containing ligand covalently bonded through an organic spacer silicon grouping to a solid inorganic support. The thiol and/or thioether aralkyl nitrogen-containing ligand portion(s) of the compound has an affinity for the desired ions to form a complex thereby removing the desired ions from the source solution. The desired ions are removed from the compound by contacting the compound with a much smaller volume of a receiving solution having a greater affinity for the desired ions than does the thiol and/or thioether aralkyl nitrogen-containing ligand portion of the compound. The process is useful in removing desired or unwanted ions from Rh and Ir concentrates, acidic waste streams, multiple platinum group metal refining streams, and other industrial or environmental streams. The invention is also drawn to the thiol and/or thioether aralkyl nitrogen-containing ligands covalently bonded through a spacer grouping to a hydrophilic inorganic solid support material. The preferred aralkyl group is benzyl.
Patent JP-3856822-B2 (JP)
IPC: C07D405/14
Filed: 1995-07-05
Granted: 2006-12-13
Abstract: Described is a process for preparing chiral compounds of the formula   <IMAGE>   wherein X1 and X2 are independently F or Cl, and Y is Cl, Br or I, comprising reacting a triol of the formula   <IMAGE>etone in the presence of a catalyst, then with a halogen selected from Cl2, Br2 or I2, or N-bromosuccinimide or N-iodosuccinimide.
Patent JP-4312261-B2 (JP)
IPC: F02D45/00
Filed: 1997-07-10
Granted: 2009-08-12
Abstract: A method of controlling an internal combustion engine during a warm-up period thereof including controlling at least one operational parameter of the engine as a function of at least a certain measure of the energy delivered to the engine since the start of the warm-up period of the engine to thereby provide improved combustion stability during said warm-up period. Preferably, the measure of the energy delivered to the engine is based on the amount of fuel delivered to the engine during the warm-up period.
Patent JP-3129733-B2 (JP)
IPC: A61P25/28
Filed: 1992-02-28
Granted: 2001-01-31
Abstract: PCT No. PCT/CA92/00090 Sec. 371 Date Dec. 23, 1993 Sec. 102(e) Date Dec. 23, 1993 PCT Filed Feb. 28, 1992 PCT Pub. No. WO92/15551 PCT Pub. Date Sep. 17, 1992.The invention relates to a series of propargylamines, their salts and pharmaceutical compositions containing a compound of formula (III) wherein R1, R3 and R4 are the same or different and represent hydrogen or a straight chain or branched lower alkyl; y is an integer ranging from 0 to 5; z is an integer ranging from 0 to 5; and R2 is a straight chain or branched alkyl, alkenyl, alkynyl, alkoxy, alkylthio or alkyl sulphinyl group having from 3 to 11 carbon atoms, said group being unsubstituted or substituted with at least one of the substituents selected from hydroxy, aldehyde, oxo, loweracyloxy, halogen, thio, sulfoxide, sulfone, phenyl, halogen-substituted phenyl, hydroxy-substituted phenyl, cycloalkyl having from 3 to 6 carbon atoms and heterocyclic substituents having between 3 and 6 atoms, of which form 1 to 3 are heteroatoms selected from O, S and/or N, and pharmaceutically acceptable salts thereof, in admixture with a pharmaceutically acceptable carrier, excipient or adjuvant. The compounds are useful as selective monoamine oxidase B inhibitors and have demonstrated neuroprotective properties in human and veterinary medicine.
Patent JP-2702580-B2 (JP)
IPC: B32B27/12
Filed: 1989-05-02
Granted: 1998-01-21
Abstract: A multilayer chemical barrier fabric is made up of a base sheet of nonwoven polypropylene laminated on one side to a multilayer film sheet having a film of ethylene vinyl alcohol sandwiched between films of nylon with a surface film if linear low-density polyethylene bonded to the outer film of nylon and laminated on the other side to a multilayer film sheet having a central film of polyvinylidine chloride, an inner film of ethylene vinyl acetate, and an outer film of low-density polyethylene. Fabrics having this structure show resistance to breakthrough within eight hours for all fifteen chemicals listed on the ASTM F1001 chemical test battery. A composite fabric having the above structure, but omitting the multilayer film that contains polyvinylidine chloride, is also disclosed.
Patent JP-3153866-B2 (JP)
IPC: B22D11/06
Filed: 1997-07-09
Granted: 2001-04-09
Abstract: A method for continuously casting thin metal products, the method comprising the operations of pre-heating a pair of refractory plates (7) for the lateral containment of a bath of molten metal constituted of a pair of counter-rotating rolls (1, 2) and of abutting said pair of plates (7) towards each lateral surface of the ends of said pair of rolls (1, 2), characterized in that it comprises the operations of applying a controlled elastic or elastic/plastic deformation to said pair of plates (7) at the contacting arc between the surface of the plates (7) and the peripheral portion of the ends of said rolls (1, 2), and controlling said elastic and/or elastic-plastic deformation of said pair of plates (7) during the whole casting process, so as to minimize the surface wear of the plates (7) and of the ends of the rolls (1, 2), and to guarantee the maintainment of a predetermined distance between said rolls (1, 2) and said plates (7) lower than a predetermined value, and to minimize the occurrence of leaks-of molten metal between said plates (7) and said end parts of said rolls (1, 2).
Patent JP-2972252-B2 (JP)
IPC: A61K47/48
Filed: 1989-06-12
Granted: 1999-11-08
Abstract: Test strip having at least one patch thereon and intended for use in occlusive epicutaneous testing in order to detect contact allergy to formaldehyde. The characteristic feature is that on at least one of said at least one patch the test substance is a reversible N-formaldehyde derivative of a carboxamide or -imide, said test substance being formulated in a dry vehicle.
Patent JP-3281380-B2 (JP)
IPC: F16H57/033
Filed: 1992-10-21
Granted: 2002-05-13
Abstract: The transmission has at least two sub-assemblies, each cooperating with a selection and control mechanism (29,31). The sub-assemblies comprise modular units (180a-d), each having a different axis (Da,Db,Dc) and linked together by a mechanical connecting member (2a,1b;2b,1c). The axes of the modules are arranged parallel to each other. In the case of three or more sub-assemblies, the mechanical connectors are arranged successively on alternate sides of the transmission. The sub-assembly modules are arranged in a straight or curved series configuration, and at least some of the modules may be coaxial.