Patent SG-11201907541T-A (SG)
Title: Systems for allergen detection
Inventor: GILBOA-GEFFEN ADI
IPC: C12M3/00
Filed: 2018-02-21
Abstract: FIG12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 30 August 2018 (30.08.2018) WIPO I PCT oimiolo VIII °nolo °Nonni! om IIII iflo oimIE (10) International Publication Number WO 2018/156535 Al (51) International Patent Classification: G01N 21/64 (2006.01) GO1N 30/88 (2006.01) C12M 1/34 (2006.01) G02B 27/00 (2006.01) C12M 3/00 (2006.01) GOOK 7/12 (2006.01) (21) International Application Number: PCT/US2018/018881 (22) International Filing Date: 21 February 2018 (21.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/461,332 21 February 2017 (21.02.2017) US (71) Applicant: DOTS TECHNOLOGY CORP. [US/US]; 16 Tech Circle, 2nd Floor, Natick, Massachusetts 01760 (US). (72) Inventors: GILBOA-GEFFEN, Adi; 31 Alden Rd., Way- land, Massachusetts 01778 (US). BABU BROWN, Renu- ka; 536 Glen Road, Weston, Massachusetts 02493 (US). KINTZ, Gregory J.; 206 Wavecrest Ave., Santa Cruz, Cal- ifornia 95060 (US). YOUNG, Adam J.; 82 Monroe Street, Dedham, Massachusetts 02026 (US). MURPHY, Patrick; 16 Valentine St., Cambridge, Massachusetts 02139 (US). ANTHONY, Joshua Glenn; 39 Sunset Rock Lane, Read- ing, Massachusetts 01867 (US). FLEMING, Paul; 3595 Granada Avenue, #176, Santa Clara, California 95051 (US). GORHAM, Brett; 2540 Capitola Road, Santa Cruz, Cal- ifornia 95062 (US). GRISWOLD, Ryan; 231 Los Gatos Blvd., Los Gatos, California 95030 (US). RICHARDSON, Bruce; 14801 Golf Links Drive, Los Gatos, California 95032 (US). (74) Agent: WARD, Donna T. et al.; DT WARD, P.C., 142A MAIN STREET, GROTON, Massachusetts 01450 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (54) Title: SYSTEMS FOR ALLERGEN DETECTION (57) : The present invention is drawn to devices and systems for allergen detection in a sample. The allergen detection system includes a sampler, a disposable analysis cartridge and a detection device with an optimized optical system. In some embodiments, the allergen detection utilizes aptamer nucleic acid molecules as detection agents. In some embodiments, the nucleic acids are conjugated to magnetic beads or solid surfaces such as glasses, microwells and microchips. [Continued on next page] WO 2018/156535 Al MIDEDIMOMOIDEIREEMOMOMEMMEOMEEN SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))