baber/WOPTO huggingface dataset:
Patent JP-3330706-B2 (JP)
IPC: C07D417/14
Filed: 1993-12-09
Granted: 2002-09-30
Abstract: The invention concerns quinazoline derivatives of the formula I <CHEM> wherein m is 1, 2 or 3 and each R<1> includes hydroxy, amino, ureido, hydroxyamino, trifluoromethoxy, (1-4C)alkyl, (1-4C)alkoxy and (1-3C)alkylenedioxy; and and Q is a 9- or 10-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a further heteroatom selected from nitrogen, oxygen and sulphur, or Q is a 9- or 10-membered bicyclic aryl moiety which heterocyclic or aryl moiety may optionally bear one or two substituents selected from halogeno, hydroxy, oxo, amino, nitro, carbamoyl, (1-4C)alkyl, (1-4C)alkoxy, (1-4C)alkylamino, di-[(1-4C)alkyl]amino and (2-4C)alkanoylamino; or a pharmaceutically-acceptable salt thereof; processes for their preparation; pharmaceutical compositions containing them; and the use of the receptor tyrosine kinase inhibitory properties of the compounds in the treatment of cancer.
Patent JP-H0429794-B2 (JP)
IPC: D21C9/00
Filed: 1988-12-13
Abstract: A process for preparing mechanical pulp and/or paper containing the mechanical pulp is described, wherein an acylglycerol lipase is used. The process according to the invention avoids the problems caused by the resins in the preparation of mechanical pulp and/or paper containing said pulp.
Patent JP-3737299-B2 (JP)
IPC: H01M8/06
Filed: 1998-12-03
Granted: 2006-01-18
Abstract: PROBLEM TO BE SOLVED: To provide a conversion method for generating electric power by using a temperature difference between a combustion area and an air supply pipe peripheral wall surface, by arranging a thermoelectric conversion element on the outer periphery or an inner peripheral wall surface of an air supply pipe in the combustion area of a cylindrical solid electrolyte fuel cell, and generating electric power by using combustion heat through unreacted fuel and surplus air at fuel cell operating time. SOLUTION: Air supplied to an air supply pipe is supplied to a solid electrolyte in a cell by turning back from a lower end part of an inner tube to react with hydrogen supplied through the outer wall of the cell to generate electric power. At this time, surplus air and unreacted hydrogen burn in a combustion area by passing through clearance between the outer periphery of the cell and a lower partition wall. The combustion area is also at a high temperature, similar to a cell temperature at power generation operation time, the temperature difference is generated between the temperature and an outer wall temperature of the air supply pipe, and a temperature difference ΔT when supplying air at the normal temperature depends on a condition such as a place and a fuel utilization factor, but becomes, for example, 600 to 900 deg.C.  Additionally, electric power from a cylindrical solid electrolyte fuel cell, electric power is obtained by using the temperature difference by a thermoelectric converting element arranged on an air supply pipe outer wall surface.
Patent JP-3955626-B2 (JP)
IPC: C08K3/00
Filed: 1996-05-10
Granted: 2007-08-08
Abstract: Oxygen-scavenging compositions comprising an oxidizable metal component, an electrolyte component and a solid, non-electrolytic, acidifying component and, optionally, a water-absorbant binder and/or a polymeric resin exhibit good oxygen-scavenging performance with improved oxidation efficiency relative to compositions containing oxidizable metal component and either an electrolyte or acidifying component but not both. The compositions can be used as an oxygen absorbent in packets or in combination with thermoplastic resins melt-fabricated into a wide variety of oxygen-scavenging packaging articles.
Patent JP-2783680-B2 (JP)
IPC: A61K31/473
Filed: 1992-01-07
Granted: 1998-08-06
Abstract: There are provided compounds of the general formula (I) <CHEM> wherein R<0> represents a hydrogen or halogen atom, or a C1-4alkyl, C1-4alkoxy, C1-4alkylthio, amino or nitro group; p represents 1; or when R<0> represents C1-4alkoxy may also represent 2 or 3; R<1> represents a hydrogen or halogen atom, or a C1-4alkyl, C1-4alkoxy or C1-4alkylthio group;  R<2> represents a hydrogen atom or a C1-4alkyl group; A represents an oxygen or a sulphur atom, a bond or a group (CH2)1NR<9> (where 1 represents zero or 1 and R<9> represents a hydrogen atom or a methyl group); B represents a C1-4alkylene chain optionally substituted by a hydroxyl group, except that the hydroxyl group and moiety A cannot be attached to the same carbon atom when A represents an oxygen or sulphur atom or a group (CH2)1NR<9>, or when A represents a bond B may also represent a C2-4alkenylene chain;  R<3> represents a hydrogen atom or a C1-4alkyl group;  m represents 1 or 2; R<4> represents a hydrogen or a halogen atom, or a C1-4alkyl, C1-4alkoxy or C1-4alkylthio group;  R<5> represents a hydrogen atom or a C1-4alkoxy group; R<6> represents a hydrogen atom or a C1-4alkyl or C1-4alkoxy group R<7> represents a hydrogen atom or R<3> and R<7> together form a group -(CH2)n-where n represents 1 or 2;  R<8> represents a hydrogen atom or a C1-4alkoxy group;  the group <CHEM> is attached at the benzene ring 3 or 4 position relate to the carboxamide substituent, provided that when the group is attached at the benzene ring 3 position then R<6> must be attached at the benzene ring 6 position;  and salts and solvates thereof. The novel compounds of formula (I) can sensitize multidrug-resistant cancer cells to chemotherapeutic agents and may be formulated for use in therapy, particularly to improve or increase the efficacy of an antitumour drug.
Patent JP-H0655178-B2 (JP)
IPC: A47G1/16
Filed: 1985-04-11
Abstract: A corner holding for mirrors and similar elements includes a base element and a plurality of holding members, with the base element being adapted, by breaking along the weakening lines formed by a cross-shaped recess, to be divided into four sections, and with a shape corresponding to the shape of the holding members being provided with locking pins for the introduction into locking holes of the base element of the sections which are furthermore provided with fixing holes. The base element includes a circular plastic plate adapted for division into four sections defined by the cross-shaped recess, while the holding member includes an outwardly open pocket adapted for reception of a mirror corner so that a mirror by way of four holding members can be fixed to base elements secured to a wall surface. With the holder, a considerable simplification is realized by the mounting of a given mirrors wall since the number of base elements and holding member always corresponds to the number of mirrors. The mounting of the mirrors, for example, requires the use of a base element divided into four sections together with four holding members, while the mounting of four mirrors for a mirror wall requires the use of one entire base element, four half base elements, and four quarter base elements, that is, in total, four entire base elements and sixteen holding members.
Patent JP-3288375-B2 (JP)
IPC: F16F7/00
Filed: 1992-06-30
Granted: 2002-06-04
Abstract: PCT No. PCT/DE92/00541 Sec. 371 Date Jan. 10, 1994 Sec. 102(e) Date Jan. 10, 1994 PCT Filed Jun. 30, 1992 PCT Pub. No. WO93/01355 PCT Pub. Date Jan. 21, 1993.A shock absorber component 7 is in the form of a flatly placeable strip, plate or mat and is especially for supporting the track of railroads. The shock absorber component 7 is placed between the superstructure 2 and the roadbed 1 of the track assembly. The shock absorber component 7 includes a core layer 8 having bonded rubber particles 12 and a cover layer 10 made of flexible material. The cover layer 10 surrounds this core layer 8. The rubber particles 12 of the core layer 8 are exclusively porous and the cover layer 10 is made of a compact rubber material. The cover layer 10 is vulcanized to the core layer 8.
Patent JP-2561337-B2 (JP)
IPC: A61F/
Filed: 1988-03-30
Granted: 1996-12-04
Abstract: Means for fixing a joint prosthesis the stem of which is provided with a friction surface (2). Said means comprises a substantially homogeneous mixture of a biologically compatible granular material in which the grains (3) have a substantially even particle size distribution and are substantially irregular and/or plastic. A method for fixing said joint prosthesis consists in that a cavity is reamed in the bone in which the prosthesis is to be applied, that grains (3) of biologically compatible material are applied in said cavity so as to form a grain bed, that the prosthesis is driven down into said grain bed until substantially the entire prosthesis stem is surrounded by the grains, that the grains are subjected to an external force, and that a device (5) for retaining the grains is applied on said bed around the prosthesis stem. <IMAGE>
Patent JP-3053428-B2 (JP)
IPC: A61K31/42
Filed: 1991-01-09
Granted: 2000-06-19
Abstract: Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof and pharmaceutical compositions containing such compounds are useful for treating inflammatory diseases in mammals.
Patent JP-3267969-B2 (JP)
IPC: D06P1/673
Filed: 1991-12-20
Granted: 2002-03-25
Abstract: A hydrophilic polymer, e.g., provided as a contact lens, is tinted by a method which incorporates a reactive dye into the polymer during formation of the latter. Following physical entrainment of the reactive dye in the polymer, the polymer is contacted with an aqueous solution of a base which catalyzes the reaction of the dye with the polymer. In this way, the dye becomes permanently covalently bound to the polymer.
Patent JP-3672041-B2 (JP)
IPC: H01J63/06
Filed: 1994-07-20
Granted: 2005-07-13
Abstract: A resonant microcavity display, comprising a thin-film resonant microcavity with a phosphor active region is disclosed. The microcavity comprises: a rigid substrate; a front reflector disposed upon the rigid substrate; a phosphor active region disposed upon the front reflector; and a back reflector disposed upon the active region. The display preferentially emits light that propagates along the axis perpendicular to plane of the display, due to its quantum mechanical properties. It exhibits high external efficiency, highly controllable chromaticity, high resolution, highly directional output and highly efficient heat transfer characteristics. For these reasons it provides a suitable display element for projection screen television, high definition television, direct view television, flat panel displays, optical coupling, and other applications.
Patent JP-2719233-B2 (JP)
IPC: A61P5/00
Filed: 1992-03-17
Granted: 1998-02-25
Abstract: PCT No. PCT/EP92/00572 Sec. 371 Date Jan. 17, 1994 Sec. 102(e) Date Jan. 17, 1994 PCT Filed Mar. 17, 1992 PCT Pub. No. WO92/19651 PCT Pub. Date Nov. 12, 1992.A luteinizing hormone releasing hormone antagonist peptide is provided which effectively decreases plasma levels of estrogens and androgens. The peptide exhibits increased levels of potency while at the same time minimizing histamine releasing properties, vascular permeability (or edematogenic effects), hypotension, poor water solubility an inadequate duration of action associated with luteinizing hormone releasing hormone antagonist peptides of the past.
Patent JP-3519082-B2 (JP)
IPC: B32B3/12
Filed: 1993-08-02
Granted: 2004-04-12
Abstract: An elastic, three-dimensional, fluid pervious, polymeric web is provided for use as a topsheet on an absorbent article. The web has a plurality of beam-like elements connected to one another forming apertures in the web. A plurality of the beam-like elements have permanently deformed sections which allow the web to extend when the web is subjected to tension providing an increased elasticity to the web.
Patent JP-3128237-B2 (JP)
IPC: A61F2/64
Filed: 1991-03-28
Granted: 2001-01-29
Abstract: PCT No. PCT/SE91/00240 Sec. 371 Date Oct. 1, 1992 Sec. 102(e) Date Oct. 1, 1992 PCT Filed Mar. 28, 1991 PCT Pub. No. WO91/15170 PCT Pub. Date Oct. 17, 1991.An artificial knee-joint provided with linkage mechanisms, where a thigh part and a lower-leg part are mutually connected by tow base linkage arms, each of which is pivotally connected at respective ends with both the lower-leg part and the thigh part, wherein the pivotal attachment points of the lower-leg part are disposed in moveable attachment elements which mutually coact in a manner such that the knee-joint will automatically either adopt a substantially locked or a moveable position, depending on the direction of the load acting on the knee-joint. The first attachment element is pivotally connected to the two base linkage arms extending from the thigh part and has three pivot points, whereas the second attachment element has two pivot points. The back base linkage arm extending from the thigh part is pivotally connected to both attachment elements. The second attachment element is provided with a lock-stop device which limits movement of the attachment element. When walking, the movement of the attachment elements function to automatically lock the knee-joint and to terminate a walking step in a natural fashion.
Patent JP-3250806-B2 (JP)
IPC: C07B57/00
Filed: 1992-10-21
Granted: 2002-01-28
Abstract: The present invention is directed to a compound of the formula (I)   <CHEM>  wherein R represents a hydrogen atom or an acyl, aroyl or cycloalkylcarbonyl radical or a residue of formula <CHEM>     R<5> represents an alkyl radical; R<6> represents an aryl or heteroaryl radical, or R<5> represents an alkylene chain attached to a carbon atom in an ortho position of the R<6> aryl or heteroaryl radical relative to a carbon of the R<6> aryl or heteroaryl radical linked to the propanoyl moiety; R<7> represents a hydrogen atom or an alkyl, aryl, alkoxy or aryloxy radical; and R' represents a hydrogen atom or an alkyl, aralkyl, acyl or aroyl radical;     and the pharmaceutically acceptable salts thereof. The invention is also directed to the preparation of these compounds, pharmaceutical compositions comprising the compounds and methods for their pharmaceutical use.
Patent JP-2513880-B2 (JP)
IPC: H01L33/00
Filed: 1989-07-12
Granted: 1996-07-03
Abstract: A method of making an opto-electronic component (13) comprises inserting a pre-assembled device carrier (1) into a mould, filling the mould (2) with light and/or thermally curable material, optically aligning the device assembly and, on achieving optical alignment, at least partially curing the material.
Patent JP-3294616-B2 (JP)
IPC: A61P29/00
Filed: 1996-08-08
Granted: 2002-06-24
Abstract: The present invention addresses 2-substituted aryl pyrroles, as well as compositions containing such compounds and methods of treatment. Cytokine mediated diseases refers to diseases or conditions in which excessive or unregulated production or activity of one or more cytokines occurs. Interleukin-1 (IL-1), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Tumor Necrosis Factor (TNF) are cytokines which are involved.
Patent JP-2902115-B2 (JP)
Inventor: GAETA LAURA S L
IPC: C07K14/00
Filed: 1992-11-19
Granted: 1999-06-07
Abstract: (A) An agonist analogue of amylin having aminoacid sequence (I) is claimed. In (I) A1 is Lys, Ala, Ser or H; B1 is Ala, Ser or Thr; C1 is Val, Leu or Ile; D1 is His or Arg; E1 is Ser or Thr; F1 is Ser, Thr, Gla or Asn; G1 is Asn, Gln or His; H1 is Phe, Leu or Tyr; I1 is Ala or Pro; J1 is Ile, Val, Ala or Leu; K1 is Ser, Pro, Leu, Ile or Thr; L1 is Ser, Pro or Thr; M1 is Asn, Asp, Gln or Asn; X, Y are residues having side chains which are chemically bonded to each other to form an intramolecular linkage; and Z is amino, alkylamino, dialkylamino, cycloalkylamino, arylamino, aralkylamino, alkoxy, aryloxy or aralkyloxy, with provisos. The peptides are pref. prepd. by solid phase synthesis. Pref. peptides include 25,28,29 Pro-h-amylin (Ia), des-'Lys 25,28,29 Pro-h-amylia and 18 Arg 25,28 Pro-h-amylin.
Patent JP-H066141-B2 (JP)
IPC: A61F13/00
Filed: 1989-09-14
Abstract: A wound dressing (10) is described which includes a flexible backing member (14) that can be vacuum formed to include a depression. A pressure-sensitive adhesive layer (16) extends across the depression side of the flexible backing member. A hydrogel material (12) is positioned in the depression of the flexible backing member and a release liner (18) extends over the exposed pressure-sensitive adhesive layer and the exposed hydrogel material, which release liner has a selective releasability whereby it can be removed from the wound dressing intact, leaving a portion of the pressure-sensitive adhesive and the hydrogel material exposed.
Patent JP-3944243-B2 (JP)
IPC: A61B17/04
Filed: 1997-08-13
Granted: 2007-07-11
Abstract: The suturing system includes a cannula that defines two adjacent lumens. One lumen carries a supply of anchor members that are joined together by a suture. The anchor members are moved by a supply rod, one at a time, from a lower lumen to an upper lumen. The upper lumen terminates in a sharpened tip that is pierced through tissue. The single anchor member that is moved into the upper lumen is then deployed into or behind the pierced tissue and the cannula is retracted. The rod for deploying the anchor member also temporarily blocks movement of additional anchor members from the lower to the upper lumen so that the surgeon can sufficiently tense the suture before piercing the tissue in an adjacent location and depositing a second anchor member. A series of anchor members joined by a continuous suture are deposited in this matter to suture together tissue. Also provided is a gun to which the cannula is mounted for one-handed operation of the system.
Patent JP-2823690-B2 (JP)
IPC: C12N15/18
Filed: 1991-07-22
Granted: 1998-11-11
Abstract: PDGF B-chain polypeptides characterized by the substitution or deletion of a lysine or arginine residue at position 27, 28, 32, 79, 80 or 81 of native B-chain are disclosed. Also disclosed are PDGF-like proteins containing the B-chain polypeptides. The polypeptides and proteins may be produced through the use of cultured cells transfected or transformed to express DNA molecules that encode the polypeptides. The PDGF-like proteins are useful as components of cell culture media and for accelerating the healing of wounds.
Patent JP-3149946-B2 (JP)
IPC: A61K38/095
Filed: 1990-09-14
Granted: 2001-03-26
Abstract: The present invention provides methods and compositions for inducing penile erections, sufficient for vaginal penetration, in a human male suffering from impotence. When the impotence is substantially only neurogenic, psycogenic or neurogenic and psychogenic, a method of the invention comprises (A) administering to the male by intracavernosal injection peptide N-terminal histidine C-terminal methionineamide and (B) sexually stimulating the male. When the impotence is caused by severe atherosclerosis, a method of the invention comprises (A) administering to the male by intracavernosal injection an amount of a physiologically acceptable composition comprising (1) a neuropeptide selected from the group consisting of human vasoactive intestinal peptide and peptide N-terminal histidine C-terminal methionineamide and (2) an alpha-adrenergic blocker, such as phentolamine or prazosin, and (B) sexually stimulating the male. The invention also entails a physiologically acceptable composition suitable for use in inducing, upon administration by intracavernosal injection, an erection, sufficient for vaginal penetration, in a human male suffering from impotence, which is caused by severe atherosclerosis, which composition comprises (1) a neuropeptide selected from the group consisting of vasoactive intestinal peptide and peptide N-terminal histidine C-terminal methionineamide and (2) an alpha-adrenergic blocker, such as phentolamine or prazosin.
Patent JP-3272727-B2 (JP)
IPC: C07D209/30
Filed: 1994-11-16
Granted: 2002-04-08
Abstract: A propenone derivative represented by general formula (I) and a pharmacologically acceptable salt thereof, wherein R<1> represents hydrogen, lower alkyl, lower alkanoyl, lower alkoxycarbonyl, lower alkylsulfonyl, aralkyl, (un)substituted aroyl, (un)substituted arylsulfonyl, (un)substituted heteroarylcarbonyl, (un)substituted heteroarylsulfonyl, diglycolyl or a group of formula (a), R<2> represents hydrogen, lower alkyl, halogen, (un)substituted aryl or (un)substituted heteroaryl; R<3> represents hydrogen, lower alkyl or (un)substituted aryl; and R<4>, R<5>, R<6> and R<7> represent each independently hydrogen, lower alkyl, lower alkoxy, aralkyloxy, hydroxy, nitro, halogen, trifluoromethyl or -NR<8>R<9>, wherein R<8> and R<9> represent each independently hydrogen, lower alkyl, lower alkanoyl, lower alkoxycarbonyl or (un)substituted aroyl. <CHEM>
Patent JP-3007907-B2 (JP)
IPC: H04Q3/545
Filed: 1993-12-29
Granted: 2000-02-14
Abstract: A telecommunications switch which may be configured to provide a variety of user-programmable communications or call processing services. Such services may be dynamically provided to any port served by the switch without reducing the number of time slots that would otherwise be available for calls. The switch includes a CPU/matrix card, one or more line cards for terminating analog or digital lines or trunks, and one or more programmable communications services cards, all of which are connected in communicating relationship by a series of buses. Each communications services card is independently programmable and includes a processor for processing messages received from the CPU/matrix card. The communications services card provides a basic platform onto which different types of modules may be mounted to meet the requirements of a particular application. One or more digital signal processing modules for performing tone generation, tone reception and call progress analysis may be mounted on a single communications services card. An ISDN PRI server module provides a centralized packet engine which, when programmed in an appropriate fashion, may be used as an ISDN D channel server or to provide packet switching services. Modules for performing other services such as speech recognition, ADPCM compression or tone generation may also be installed on the basic platform.
Patent JP-3142293-B2 (JP)
IPC: E04G1/20
Filed: 1991-08-28
Granted: 2001-03-07
Abstract: The invention relates to an arrangement in an elongated working platform (2) which at each end is carried by a mast via a drive support (8) movable along the mast. The drive support includes an electric motor unit by means of which the drive support is drivable along the mast, said drive support pivotally carrying the corresponding end of the platform. At each motor unit an operating means for manual release of a motor brake for lowering the platform in case of power failure, is connected to a levelling device (24-38). The levelling device is arranged to be triggered in order to prevent movement of a drive support resulting in deviation of the platform from a position essentially corresponding to the horizontal position, said transmission being arranged to return the operating means to a position activating the motor brake, if the manual release of the motor brake causes triggering of the levelling device.
Patent JP-3611328-B2 (JP)
IPC: B65H1/08
Filed: 1994-05-17
Granted: 2005-01-19
Abstract: The invention relates to a cassette (K) for use in a device for manufacturing booklets, each booklet comprising a cover (A) made up from two cover sheets with a spine therebetween and a sheaf of papers (B) inserted between the cover sheets. According to the invention, the cassette (K) contains a stack of covers (A), all of which are brought together such that the inside of the spine of a cover is located opposite the outside of the spine of an adjacent cover. The cassette (K) is provided with a first opening (K1) through which the covers may be fed out, and support means (K3) holding the stack of covers in a selected position in the cassette, The invention also relates to the filling of such a cassette. <IMAGE>