baber/WOPTO huggingface dataset:
Patent WO-2020243166-A1 (WO)
Inventor: IYER SMITA S
IPC: A61K39/21
Filed: 2020-05-27
Abstract: The present disclosure provides methods and compositions for enhancing an immune response in a subject undergoing HIV vaccination. In particular, the present disclosure provides adjuvants and methods for increased Th1 polarization of T cells in a subject in order to enhance the immune reaction against an HIV antigen.
Patent WO-2020263582-A1 (WO)
Inventor: TSAI CHIA-YANG
IPC: G06T5/00
Filed: 2020-06-11
Abstract: The disclosed method may include (1) receiving an input datum to be processed using a non-linear function to produce an output datum, (2) comparing the input datum to a plurality of indexes of a lookup table, where the indexes designate input endpoints of a plurality of piecewise-linear sections approximating the non-linear functions, and where the lookup table further includes, for each of the indexes (a) a slope of the piecewise-linear section corresponding to the index, and (b) an axis intercept of the piecewise-linear section corresponding to the index (2) selecting, based on comparing the input datum to the plurality of indexes, an index that designates the piecewise-linear section associated with the input datum, and (4) calculating, using the slope and the axis intercept corresponding to the selected index, the output data corresponding to the input datum. Video processing systems employing such a method are also disclosed.
Patent WO-2020264114-A1 (WO)
Inventor: BOVA ANTHONY S
IPC: C08G65/40
Filed: 2020-06-25
Abstract: A solid multiphase polymer blend material comprising: (i) a polyphenolic substance having a molecular weight of at least 500 g/mol; and (ii) a polyester having a molecular weight of at least 500 g/mol; wherein at least a portion of the polyphenolic substance is covalently bonded directly or through a linking moiety to the polyester. Methods for producing the blend material are also described, e.g., homogeneously melt blending a mixture comprising components (i) and (ii) under conditions resulting in covalent attachment of at least a portion of the polyphenolic substance directly or through a linking moiety to the polyester. Methods for producing objects made of the blend material by melt extrusion are also described.
Patent WO-2021007168-A1 (WO)
Inventor: LEI YUGUO
IPC: A61L27/38
Filed: 2020-07-06
Abstract: Embodiments of the disclosure provide a dissolvable or degradable artificial circulation system for engineering, culturing, and integrating large volume tissues. Also provided are methods of using large engineered tissues prepared using the degradable artificial circulation system for clinical applications and for various applications such as large-scale production of therapeutic or consumable products, drug discovery, and toxicity screening.
Patent WO-2021011491-A1 (WO)
Inventor: KRASIK GALINA
IPC: G16B40/20
Filed: 2020-07-13
Abstract: Systems and methods for disease diagnosis through the detection of multiple biomarkers by receiving concentration values of biomarkers, building a training set using the samples of the biomarkers, and performing correlation calculations on the biomarker concentration values to diagnose the disease.
Patent WO-2021021660-A1 (WO)
Inventor: POESS BERNHARD
IPC: G06F11/14
Filed: 2020-07-24
Abstract: In one embodiment, a method includes generating a handle that references a checkpoint for a service, sending the handle to the service, wherein the handle is configured to be used by the service to store one or more states of the service in the checkpoint, determining that the service needs to be restarted, restarting the service, accessing the handle for the checkpoint, and sending the handle for the checkpoint to the restarted service, wherein the handle for the checkpoint is configured to be used by the restarted service to restore the one or more states.
Patent WO-2021026056-A1 (WO)
Title: Ébauches de masque euv et procédés de fabrication
Inventor: XIAO WEN
IPC: G03F1/52
Filed: 2020-08-03
Abstract: Un élément réfléchissant les ultraviolets extrêmes comprend un empilement multicouche de couches absorbantes sur un empilement multicouche de couches réfléchissantes. L'élément comprend une couche d'espacement et une couche d'accord de phase. L'invention concerne également des procédés de fabrication d'éléments réfléchissant les ultraviolets extrêmes et des systèmes de lithographie comprenant des éléments réfléchissant les ultraviolets extrêmes.
Patent WO-2021030724-A1 (WO)
Inventor: ZHONG TIAN
IPC: H01L21/00
Filed: 2020-08-14
Abstract: Technologies for a strong rare-earth-ion interactions are disclosed. In the illustrative embodiment, a heterogeneous slot waveguide is formed with two layers of silicon surrounding a layer of Er:Y2O3, resulting in a waveguide that supports a TM mode with a strong confinement of electromagnetic field near the erbium dopants. The strong concentration of electromagnetic field and small mode volume allows for strong interactions between optical fields and the erbium dopants. In some embodiments, the slot waveguide structure may be configured as a microring resonator or a photonic crystal, resulting in small-mode-volume resonators with high Q-factors. In some embodiments, strong electro-optic and/or acousto-optic coupling may be achieved, resulting in quantum transducer able to coherently convert between signals in different systems.
Patent WO-2021030804-A1 (WO)
Inventor: JEON HYOUNGSUK
IPC: H04W74/08
Filed: 2020-08-17
Abstract: A wireless device transmits (3210) a first preamble via a cell. The wireless device receives (3220) a downlink grant for a random access response. The wireless device determines (3230) a failure to receive the random access response. The wireless device determines (3240), based on the failure and a time alignment timer of the cell, an uplink signal for transmission via the cell. The uplink signal is one of a second preamble and a negative acknowledgement. The wireless device transmits (3250) the uplink signal.
Patent WO-2021034778-A1 (WO)
Title: Carton and carton blank therefor
Inventor: PADILLA JESUS
IPC: B65D5/72
Filed: 2020-08-17
Abstract: Aspects of the disclosure relate to a carton and to a blank for forming the carton. The carton comprises a plurality of walls defining an interior for receiving the one or more articles. One of the plurality of walls includes an inner wall panel and an outer wall panel spaced apart from the inner wall panel to define a void therebetween. The carton comprises a dispenser having an inner dispensing opening provided in the inner wall panel and an outer dispensing opening provided in the outer wall panel and at least partially in registry with the inner dispensing opening to provide a dispenser opening for access to the interior of the carton. The dispenser comprises a slide panel disposed in the void between the inner wall panel and the outer wall panel.
Patent WO-2021035147-A1 (WO)
Title: Planning and control framework with communication messaging
Inventor: LUND BENJAMIN
IPC: G08G1/005
Filed: 2020-08-21
Abstract: Disclosed is a method and apparatus for operating a first device. The first device obtains environment information in proximity to the first device and receives one or more communication messages from a second device and the message(s) includes relevance criteria, wherein the relevance criteria indicates one or more devices, one or more sets of device characteristics, one or more lanes, one or more intersections or areas, one or more pedestrian paths or bicycle paths, one or more signal characteristics from the second device or any combination thereof. The first device determines whether the one or more communication messages are relevant to the first device based on the relevance criteria and the environment information and performs an operation in response to the determination of whether the one or more communication messages are relevant.
Patent WO-2021041250-A1 (WO)
Inventor: KEYT BRUCE
IPC: A61K39/395
Filed: 2020-08-21
Abstract: La présente invention concerne une molécule de liaison dérivée d'IgM isolée, par exemple, un anticorps IgM, un anticorps du type IgM ou une autre molécule de liaison dérivée d'IgM, comprenant au moins une chaîne lourde dérivée d'IgM variante, ladite chaîne lourde dérivée d'IgM variante comprenant une région constante de chaîne lourde d'IgM variante associée à un domaine de liaison qui se lie spécifiquement à une cible, au moins un motif de glycosylation lié à (N) de l'asparagine de la région constante de chaîne lourde d'IgM variante subissant une mutation pour empêcher la glycosylation au niveau de ce motif, et/ou au moins un motif de glycosylation lié à N étant introduit dans la chaîne lourde d'IgM variante.<i />
Patent WO-2021050920-A1 (WO)
Title: Ethylene oxide scrubbing sheet
Inventor: WARBURTON P RICHARD
IPC: B01D53/46
Filed: 2020-09-11
Abstract: An ethylene oxide (EtO) scrubbing sheet for the removing fugitive EtO emissions from, for example, sterilized medical devices and leaks from chemical plants. The scrubbing sheet comprises an acid impregnated layer, a second layer impregnated with an acid neutralizer, combined inside a gas porous protective membrane.
Patent WO-2021071628-A1 (WO)
Title: Conformal titanium nitride-based thin films and methods of forming same
Inventor: MUKHERJEE NILOY
IPC: C23C16/04
Filed: 2020-09-14
Abstract: The disclosed technology generally relates to forming a titanium nitride-based thin films, and more particularly to a conformal and smooth titanium nitride-based thin films and methods of forming the same. In one aspect, a method of forming a thin film comprising one or both of TiSiN or TiAIN comprises exposing a semiconductor substrate to one or more vapor deposition cycles at a pressure in a reaction chamber greater than 1 torr, wherein a plurality of the vapor deposition cycles comprises an exposure to a titanium (Ti) precursor, an exposure to a nitrogen (N) precursor and an exposure to one or both of a silicon (Si) precursor or an aluminum (Al) precursor.
Patent WO-2021055503-A1 (WO)
Title: Ion exchange membrane for a redox flow battery
Inventor: HAMMAD AHMAD D
IPC: B01D71/52
Filed: 2020-09-16
Abstract: Embodiments provide a redox flow battery, an ion exchange membrane for use in the redox flow battery, and a method for producing the ion exchanger membrane. The ion exchange membrane includes a base layer, a first hydrophobic layer, and a second hydrophobic layer. The base layer includes sulfonated poly(ether ether ketone). The base layer has a first surface and a second surface. The first hydrophobic layer includes a polydimethylsiloxane elastomer. The first hydrophobic layer is positioned on the first surface of the base layer. The second hydrophobic layer includes the polydimethylsiloxane elastomer. The second hydrophobic layer is positioned on the second surface of the base layer. The ion exchange membrane is configured to prevent cross contamination of the first electrolyte and the second electrolyte. The redox flow battery includes a first half-cell, a second half-cell, and the ion exchange membrane. The first half-cell includes a first electrolyte. The second half-cell includes a second electrolyte. The first half-cell and the second half-cell are configured to undergo a redox reaction to discharge and charge the redox flow battery.
Patent WO-2021067859-A1 (WO)
Title: 5-fluoronicotinamide derivatives and uses thereof
Inventor: MANDEGAR MOHAMMAD A
IPC: A61K31/496
Filed: 2020-10-02
Abstract: Provided herein is a compound of Formula (I), or pharmaceutically acceptable salt thereof, wherein R 1 , Y, X, and n are defined herein. Also provided herein are compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof, and methods of using a compound of Formula (I) or pharmaceutically acceptable salt thereof, e.g., in the treatment of heart disease.
Patent WO-2021086733-A1 (WO)
Inventor: WHITTEN CHRISTOPHER
IPC: G06F8/34
Filed: 2020-10-23
Abstract: A visual bot designer displays a user interface that has a visual authoring canvas and a property pane. It can also have a serialized file display pane. A user can provide authoring inputs on any of the user interfaces, and the visual bot designer computing system generates and displays updates on the other parts of the user interface.
Patent WO-2021087259-A1 (WO)
Inventor: REGAN CONNOR
IPC: B60B35/00
Filed: 2020-10-30
Abstract: In one aspect of the present disclosure, a wheel hub assembly is provided that includes a hub body having an outboard end portion and an inboard end portion, a bearing assembly, and a seal. The seal includes a seal case and a sleeve. The hub body and seal case are rotatable relative to the sleeve. The wheel hub assembly further includes a stop of the bearing assembly configured to resist movement of the sleeve toward the outboard end portion of the hub body as the hub body, bearing assembly, and sleeve are advanced together in an inboard direction along a vehicle spindle. The stop permits the bearing assembly to transfer a force applied in an inboard axial direction against the bearing assembly, such as by tightening of a spindle nut, to the sleeve and urge the sleeve along a vehicle spindle.
Patent WO-2021108116-A1 (WO)
Title: Dispositifs et systèmes pour réduire l'activation prématurée d'une sécurité d'aiguille
Inventor: SCHERICH MEGAN
IPC: A61M25/06
Filed: 2020-11-09
Abstract: Système de cathéter (10) comprenant un ensemble cathéter (12), qui comporte un adaptateur de cathéter (14) et un cathéter (22) s'étendant de à partir de l'adaptateur de cathéter. Le système de cathéter comprend un ensemble aiguille (24), qui comporte un corps (36), une embase d'aiguille (26) disposée de façon coulissante à l'intérieur du corps, et une aiguille d'introduction (28) fixée à l'intérieur de l'embase d'aiguille et s'étendant à travers le cathéter. L'ensemble aiguille comprend une surface d'arrêt accouplée au corps et un verrou d'activation (40) qui peut coulisser d'une première position à une seconde position par rapport au corps. Lorsque le verrou d'activation se trouve dans la première position, la surface d'arrêt peut entrer en contact avec le verrou d'activation et l'abaissement du verrou d'activation peut ainsi être empêché. Lors du coulissement du verrou d'activation de la première position à la seconde position, la surface d'arrêt ne peut pas entrer en contact avec le verrou d'activation qui peut ainsi s'abaisser.
Patent WO-2021118888-A1 (WO)
Inventor: AGARD RYAN
IPC: A61M5/142
Filed: 2020-12-04
Abstract: A drug-delivery device is provided including a drug reservoir configured to contain a fluid drug, a needle cartridge comprising a plurality of needle assemblies, a drive member, a pump, one or more springs, a loading button and a dosing button. The device is configured to use work done by the user in actuating the loading button to load the one or more springs. When the user actuates the dosing button after actuating the loading button, the device is configured to (i) release the one or more loaded springs to operate the drive member to drive a needle assembly that is in operational alignment with the drive member from a retracted position to an injection position, (ii) drive the pump to pump fluid drug from the drug reservoir through the driven needle assembly, and (iii) retract the driven needle assembly from the injection position to the retracted position.
Patent WO-2021042108-A1 (WO)
Title: Estimation de taux d'erreur binaire et correction d'erreur et systèmes, procédés et dispositifs associés
Inventor: CHEN DIXON
IPC: H04L25/49
Filed: 2020-08-04
Abstract: L'invention concerne des dispositifs de couche physique et des procédés associés permettant de déterminer des taux d'erreur binaire (BER) et de corriger des erreurs dans des signaux reçus par l'intermédiaire de supports de transmission partagés de réseaux locaux sans fil. Un dispositif de couche physique est configuré pour identifier des violations de codage dans un signal reçu, déterminer un taux des violations de codage dans le signal, et estimer un BER du signal pour qu'il soit égal au taux déterminé des violations de codage. Un dispositif de couche physique est configuré pour inverser un demi-symbole précédant ou suivant immédiatement une violation de codage sur la base, au moins en partie, des intégrités de signal du demi-symbole précédant immédiatement et du demi-symbole suivant immédiatement la violation de codage pour corriger une erreur binaire.
Patent WO-2021142341-A1 (WO)
Title: Autonomous control system and method using embodied homeostatic feedback in an operating environment
Inventor: BROWN MATTHEW
IPC: G06N3/08
Filed: 2021-01-08
Abstract: A machine-learning control system comprising an operating environment and a sensorium informationally coupled the operating environment. The sensorium comprises a set of sensors and a set of motors, both informationally coupled to a homeostatic network capable of achieving ultrastability within the operating environment. The control system builds a generative model of the operating environment by extracting, through sensorimotor feedback, state information relevant to network ultrastability associated with a particular control behavior and a set of environmental parameters identified within the operating environment. A modulating sensorimotor carrier wave signal may optionally be used to increase training speed of the machine-learning control system. The control system is adaptable to a variety of engineering solutions for autonomous control systems and data processing, such as, for example, autonomous vehicles, robotics, calibration, language processing, and computer vision. A homeostatic network debugger and automatic network topology generation algorithms using node-splitting conditions and functions are also described.
Patent WO-2021146266-A1 (WO)
Title: Methods and compositions for cancer immunotherapy
Inventor: DIAZ LUIS ALBERTO
IPC: A61P37/04
Filed: 2021-01-13
Abstract: In some embodiments the present invention provides methods useful for the treatment of MMR-proficient and/or microsatellite stable (MSS) cancers and also useful for enhancing the immunogenicity of MMR-proficient and/or microsatellite stable (MSS) cancer cells, enhancing the sensitivity of MMR-proficient and/or microsatellite stable (MSS) cancer cells to immune checkpoint blockade, inducing an MMR-deficient mutational signature in MMR-proficient and/or microsatellite stable (MSS) cancer cells, and/or increasing the frequency of both missense and InDel mutations in MMR-proficient and/or microsatellite stable (MSS) cancer cells. In some embodiments such methods involve administration of a combination of temozolomide and cisplatin, or a combination of temozolomide, cisplatin and an immune checkpoint inhibitor, to a subject in need thereof.
Patent WO-2021154682-A1 (WO)
Title: Tissue dosing for intraluminal local drug delivery
Inventor: CRAIG BRIAN H
IPC: A61K9/14
Filed: 2021-01-26
Abstract: Devices, systems and methods for localized delivery of a chemotherapy, hormonal therapy or targeted drug/biologic therapy to a target tissue area of an internal body organ of a patient. A catheter forms a sealed treatment chamber in a natural lumen extending through the target tissue area. Air is purged from the chamber, which is then filled with a liquid drug solution for an adequate treatment session time, solution volume and drug concentration to saturate the target tissue area, thereby providing the treatment. The drug concentration in the liquid soaking solution may be formulated to approximate the known maximum plasma concentration achieved during systemic delivery of the same drug. An integrated pressure relief circuit may be included to avoid unsafe pressure levels in the isolated chamber. The chamber is evacuated at the end of the treatment session.
Patent WO-2021162948-A1 (WO)
Title: Variable compression body anchor
Inventor: HUBER MEGHAN
IPC: A61H1/00
Filed: 2021-02-05
Abstract: In some embodiments, a body anchor for supporting an assistive device can include: a cuff to exert a compression force on a body part of a user; and one or more tensile elements having first ends and second ends. The first ends of the tensile elements can be configured to be attached to the assistive device. The second ends of the tensile elements can be arranged about the cuff to cause the compression force to vary in proportion to a load exerted by the assistive device.
Patent WO-2021168047-A1 (WO)
Title: Chocolate composition
Inventor: BAREY VANESSA
IPC: A23G1/48
Filed: 2021-02-18
Abstract: The present invention relates to a chocolate composition comprising at least 30 weight% of cocoa solids and less than 2 weight% of milk solids, based on the total weight of the chocolate composition, characterized in that it further comprises 0.5-15 weight% plant-based protein and 0.5-10 weight% of a plasticizer ingredient, wherein the chocolate composition is substantially free from soy protein.
Patent WO-2021173715-A1 (WO)
Inventor: BLAZEK PAUL
IPC: G06N3/00
Filed: 2021-02-24
Abstract: A computer-implemented technique for training an artificial neural network is disclosed. The technique includes obtaining a training sample for training the artificial neural network; determining multiple sub concepts within the training sample; processing the sub concepts to obtain differential neurons associated with the sub concepts, wherein the differential neurons provide a relative distinction between the sub concepts; integrating the differential neurons to obtain sub concepts neurons, wherein the sub concepts neurons provide an absolute distinction of sub concepts; and integrating the sub concepts neurons to obtain concept neurons that form an output of the neural network.
Patent WO-2021178484-A1 (WO)
Inventor: FANG SAMUEL
IPC: A61F2/30
Filed: 2021-03-03
Abstract: Implant systems and methods treatment of a joint include a distal portion, a middle portion, and a proximal portion. The distal portion may include a thread having a first thread minor, a first thread major, and a first pitch. The distal portion also may have a reverse cut, helical fenestration formed through the thread. The middle portion may be devoid of threads and may include a porous outer surface structure to promote bony integration, the porous outer surface structure having a leading end and a trailing end, with the leading end having a diameter larger than the first thread minor. The proximal portion may include a proximal thread having a second thread minor, a second thread major, and a second pitch. The second thread minor may be substantially the same width as the trailing end of the middle portion.
Patent WO-2021194705-A1 (WO)
Title: Casier de tête modulaire motorisé
Inventor: BUTLER BRIAN A
IPC: A61B17/70
Filed: 2021-03-03
Abstract: La présente invention concerne des systèmes, des instruments et des méthodes d'utilisation d'un instrument chirurgical. Les méthodes comprennent : la réception d'au moins une partie d'un objet externe dans un évidement d'une tige creuse ; la rotation d'un premier arbre disposé à l'intérieur de la tige creuse ; l'utilisation de la rotation du premier arbre pour provoquer un mouvement de translation d'un second arbre de l'instrument chirurgical dans une première direction à l'opposé du premier arbre et le long d'un axe central de l'instrument chirurgical ; l'application d'une force de poussée sur l'objet externe à l'aide du second arbre qui subit le mouvement de translation ; et l'entraînement d'un mouvement de translation du second arbre dans une seconde direction opposée à la première direction après que la force de poussée ait été appliquée à l'objet externe.