baber/WOPTO huggingface dataset:
Patent CA-2902172-A1 (CA)
Inventor: MURPHY ANDREW J
IPC: C07K16/24
Filed: 2014-03-12
Abstract: The present invention provides antibodies that bind to interleukin-33 (IL-33) and methods of using the same. The invention includes antibodies that inhibit or attenuate IL-33-mediated signaling. The antibodies of the invention may function to block the interaction between IL-33 and ST2. Alternatively, certain antibodies of the invention inhibit or attenuate IL-33-mediated signaling without blocking the IL-33/ST2 interaction. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human IL-33 with high affinity. The antibodies of the invention are useful for the treatment of diseases and disorders associated with IL-33 signaling and/or IL-33 cellular expression, such as inflammatory diseases, or allergic diseases.
Patent CA-2902367-A1 (CA)
Title: Device for controlling and balancing currents for dc/dc converters
Inventor: GARCIA SOTO GUILLERMO
IPC: H02M3/158
Filed: 2014-02-25
Abstract: L'invention concerne un dispositif de régulation et équilibrage des courants pour des convertisseurs DC/DC, entre une première et une seconde sources de tension, qui comprend : - n convertisseurs (C1, C2...Cn) reliés en parallèle à la première source de tension (11), - n inductances (L1, L2...Ln), reliées en sortie à la seconde source de tension (R) au travers de n liaisons, - n capteurs de courant (22) disposés sur chacune de ces liaisons, - une seule chaîne de régulation reliée en entrée à ces n capteurs de courant (23) et en sortie à ces n convertisseurs (C1, C2...Cn).
Patent CA-2904514-A1 (CA)
Title: Catheters urinaires compacts et leurs procedes de fabrication
Inventor: MURRAY MICHAEL G
IPC: A61M25/00
Filed: 2013-03-14
Abstract: L'invention concerne un ensemble cathéter compact (10) et des procédés de fabrication d'un tel ensemble cathéter. L'ensemble cathéter comprend un récepteur (14) et un sous-ensemble cathéter (16). Le sous-ensemble cathéter comprend un élément de prise (18) et un tube de cathéter (20) porté par l'élément de prise.
Patent CA-2904589-A1 (CA)
Inventor: BALASUBRAMANIAN SHANKAR
IPC: G01N27/327
Filed: 2014-03-10
Abstract: The present invention pertains to a hemolysis sensor, a hemolysis sensor system and methods of utilizing the hemolysis sensor or hemolysis sensor system to monitor or detect hemolysis in a sample, such as a whole blood sample, a plasma sample, a serum sample or hemolyzed blood. The hemolysis sensor responds to extracellular hemoglobin levels, for example, extracellular hemoglobin in a whole blood sample as a method for detecting hemolysis in whole blood.
Patent CA-2906868-A1 (CA)
Title: Produit et traitement permettant une normalisation de viscosite de mucus
Inventor: HEIFETZ PETER B
IPC: C07K16/18
Filed: 2014-03-17
Abstract: La présente invention concerne des compositions et des méthodes permettant de diminuer la viscosité et/ou la cohésivité du mucus ou d'une expectoration et/ou d'en augmenter la liquéfaction lorsqu'il est excessivement ou anormalement visqueux ou cohésif. La composition comprend une protéine ou un peptide contenant un site actif monocystéinique de thioréxidine à un état réduit et contient en outre éventuellement un système de réduction.
Patent CA-2907948-A1 (CA)
Inventor: WADE SARAH
IPC: A61F13/496
Filed: 2014-03-12
Abstract: An absorbent article comprising first and second belts. Portions of the first belt making up the leg openings may comprise non-linear portions. And, portions of the second belt making up the leg openings comprise non-linear portions. The article may comprise a center chassis that comprises barrier leg cuffs.
Patent CA-2908778-A1 (CA)
Title: Liquid application system
Inventor: GEHRER UDO
IPC: B27N3/18
Filed: 2014-04-04
Abstract: The invention relates to a liquid application system (1) for applying liquid to a material cake (100) transported on a conveyor device (3) having a liquid application device (7), wherein the conveyor device (3) has a porous section (9) on which the material cake (100) lies or which the material cake (100) contacts and which is permeable for a liquid to be applied, wherein the liquid application device (7) has an application device (11) via which the liquid to be applied can be applied to the side of the porous section (9) of the conveyor device (3) facing away from the material cake (100), and wherein the liquid application device (7) has an over-pressure chamber (13) having a first over-pressure relative to the environment by which the porous section (9) of the conveyor device (3) passes, wherein the applied liquid can be transported via the first over-pressure through the porous section (9) of the conveyor device (3) or held via the first over-pressure to the porous section (9).
Patent CA-2909062-A1 (CA)
Title: Systems and methods for spraying an aerosol
Inventor: LORD CHARLES
IPC: G08B15/00
Filed: 2014-03-07
Abstract: A system for spraying, according to various aspects of the present invention, includes a shuttle and a trigger switch. The shuttle and the trigger switch cooperate with discontinuous mechanical coupling. The trigger switch provides a discontinuity in bias against operation of the trigger switch by the user. Consequently, the user experiences tactile feedback before spray is released. Prior to tactile feedback, the system establishes a communication link. When spray is released, the system transmits a notice via the communication link. Such a system when equipped with pepper spray aerosol is advantageous for self-defense.
Patent CA-2910737-A1 (CA)
Title: Procede de fabrication d'un raidisseur ondule de palier a feuilles et raidisseur obtenu
Inventor: ROCCHI JEROME
IPC: F16C17/02
Filed: 2014-04-29
Abstract: L'invention concerne un procédé de fabrication d'un raidisseur ondulé de palier à feuilles dans lequel on part d'une tôle (15) en superalliage austénitique à base de nickel présentant une limite d'élasticité supérieure à 500 MPa, et on soumet la tôle (15) à au moins une étape de déformation plastique en flexion par emboutissage selon toute son épaisseur avec une énergie de déformation supérieure à 10 kJ en une durée inférieure à 10-5 s de façon à créer des ondulations.
Patent CA-2913735-A1 (CA)
Inventor: BOIES DANIEL
IPC: G06F17/27
Filed: 2014-06-05
Abstract: L'invention a pour objet d'utiliser des conditions environnementales, ainsi que d'autres informations, pour adapter une réponse d'un système de dialogue conversationnel. Les conditions environnementales peuvent être utilisées à différents moments au sein du système de dialogue conversationnel. Par exemple, les conditions environnementales peuvent être utilisées pour adapter la sortie du gestionnaire de dialogue (par ex. l'action de la machine). Parmi les informations d'état du dialogue utilisées par le gestionnaire de dialogue figurent des conditions environnementales relatives au déroulement actuel du dialogue, ainsi que conditions environnementales relatives à un ou plusieurs déroulements passés du dialogue. Les conditions environnementales peuvent également être utilisées après avoir reçu l'action de la machine pour adapter la réponse communiquée à l'utilisateur. Par exemple, les conditions environnementales peuvent affecter l'action déterminée de la machine ainsi que la façon dont l'action est communiquée à l'utilisateur. Le gestionnaire de dialogue et les composants de génération de réponses du système de dialogue conversationnel utilisent chacun les conditions environnementales disponibles.
Patent CA-2916186-A1 (CA)
Title: Forced moisture evacuation for rapid baking
Inventor: DEMING MATTHEW
IPC: A21B3/04
Filed: 2014-03-10
Abstract: A baking device (10) is provided. The baking device (10) includes a housing (20) enclosing a baking compartment (12) and an air handling compartment (14), the air handling compartment (14) and the baking compartment (12) being separated by a pressure panel (30) that defines a rear wall of the baking compartment (12), the pressure panel (30) including an aperture allowing fluid communication between the baking and air handling compartments. A blower wheel (40) is mounted in conjunction with the aperture, such that rotation of the blower wheel urges air movement from the baking compartment (12) and into the air handling compartment (14). A secondary blower (50) is arranged in fluid communication with the air handling compartment (14), wherein operation of the secondary blower (50) urges ambient air into the air handling compartment (14).
Patent CA-2917850-A1 (CA)
Inventor: MCBROOM ROGER L
IPC: C12N5/04
Filed: 2016-01-18
Abstract: The present invention is in the field of soybean variety SJ1210678 breeding and development.                                                                  The present invention particularly relates to the soybean variety SJ1210678 and its progeny, and methods of making SJ1210678.
Patent CA-2919516-A1 (CA)
Inventor: BURKIN DEAN
IPC: A61K31/335
Filed: 2013-09-10
Abstract: Disclosed herein are a7ß1 integrin modulatory agents and methods of using such to treat conditions associated with decreased a7ß1 integrin expression or activity, including muscular dystrophy. In one example, methods for treating a subject with muscular dystrophy are disclosed. The methods include administering an effective amount of an a7ß1 integrin modulatory agent to the subject with muscular dystrophy, wherein the a7ß1 integrin modulatory agent increases a7ß1 integrin expression or activity as compared to a7ß1 integrin expression or activity prior to treatment, thereby treating the subject with muscular dystrophy. Also disclosed are methods of enhancing muscle regeneration, repair, or maintenance in a subject and methods of enhancing a7ß1 integrin expression by use of the disclosed a7ß1 integrin modulatory agents. Methods of prospectively preventing or reducing muscle injury or damage in a subject are also disclosed.
Patent CA-2919609-A1 (CA)
Title: Compositions and methods for improving abiotic stress tolerance
Inventor: LI ZICHAO
IPC: C07K14/415
Filed: 2014-07-29
Abstract: The present invention relates to compositions and methods for improving the abiotic stress tolerance of plants. Plants and plant parts identified, selected and/or produced using compositions and methods of the present invention are also provided.
Patent CA-2919867-A1 (CA)
Title: Oversized actuator and actuator assembly for a pressurized plastic vessel
Inventor: CARPENTER MICHAEL SCOTT
IPC: B65D47/08
Filed: 2014-07-28
Abstract: An oversized actuator and actuator assembly for a plastic vessel (or container) configured to hold a product under pressure, such as, for example, a lotion, cream, spray, ointment, gel or foam. The oversized actuator and actuator assembly are configured to be attached to what is considered to be a common, standard-sized valve cup (typically about 1.0 to 1.5 inches across) fastened to a common or standard-sized neck portion for a plastic vessel. Therefore, the actuator and actuator assembly of the present invention does not require that the shoulder of the plastic vessel to which they are attached have specialized geometry molded into the shoulder or body portions of the plastic vessel in order to hold the actuator or actuator assembly in place on the plastic vessel.
Patent CA-2920681-A1 (CA)
Title: Laminated lithium-sulfphur cell
Inventor: LINDSTROM OVE
IPC: H01M10/052
Filed: 2014-08-13
Abstract: A lithium-sulphur electrochemical cell comprising a laminate comprising: a lithium anode comprising a layer of lithium metal foil or lithium metal alloy foil; a cathode comprising an active sulphur material; a porous separator disposed between the lithium anode and the cathode;and an electrolyte; wherein: the laminate is folded in a zigzag configuration; and the cathode is offset relative to the lithium anode in the laminate, such that the cathode is accessible from one side of the laminate and the lithium anode is accessible from an opposite side of the laminate.
Patent CA-2921083-A1 (CA)
Title: Cutting device and method of making
Inventor: STOWE CALVIN J II
IPC: E21B10/46
Filed: 2014-08-15
Abstract: A cutting device includes, at least one stack of cutting elements attached to a cutter surface having, a first element and a second element attached to the cutter surface, and a third element attached to the first element and the second element, the three elements being sized and shaped such that prior to attachment to the cutter surface the three elements are restable in a stable manner on the cutter surface due to gravity alone such that a plane-defined-surface defined by one of the two planes of a modified gilmoid of the third element positioned further from the cutter surface is oriented at an angle of about 35 to 55 degrees relative to the cutter surface.
Patent CA-2921522-A1 (CA)
Title: Appareil d'eclairage encastre mince
Inventor: GHASABI AMIR
IPC: F21V29/74
Filed: 2016-02-22
Abstract: Il est décrit un dissipateur de chaleur pour un appareil d'éclairage à diode électroluminescente. Le dissipateur de chaleur comprend un boîtier configuré pour recevoir des composants électroniques de commande servant à alimenter au moins une diode électroluminescente de l'appareil d'éclairage. Le boîtier comprend un creux composé d'au moins trois lobes creux, lequel creux a une forme qui lui permet de recevoir les composants électroniques de commande lorsque le dissipateur de chaleur s'attache à l'appareil d'éclairage. Le dissipateur de chaleur comprend également une ouverture donnant sur le creux dont la configuration permet d'introduire un connecteur pour brancher les composants électroniques de commande pouvant s'introduire dans le creux sur une source d'alimentation située à l'extérieur de l'appareil d'éclairage.
Patent CA-2922343-A1 (CA)
Inventor: MITCHELL JOHN CHRISTOPHER
IPC: B01D33/70
Filed: 2014-08-28
Abstract: A liquid solid separator tank has a motor driven recirculating belt having rollers placed therein processing a mixture of materials. The top belt brings wet materials into a collection trough having overflow weirs disposed externally. These weirs permit overflow liquids to flow down towards a main tank; then, a sump pump reintroduces water back into an influent basin to cleanse the mixture once again. Also, the action of a motor driven auger within the trough forces solids towards a dewatering box attached externally thereto. This box has a motor driven rotating cage mounted on moveable rollers and internally attached removable brushes that act to clean the outer surface of the cage as it moves in addition to a stationary high pressure wash. A shroud channels the influent liquid solid mixture towards a filtered water basin disposed directly underneath the lower belt portion permitting cleansed water to be removed therefrom.
Patent CA-2922918-A1 (CA)
Title: Single use laryngoscope handle
Inventor: ELBAZ AVIRAM
IPC: A61B1/267
Filed: 2014-08-20
Abstract: Single use laryngoscope handle for use in an ISO 7376 compatible dual component laryngoscope assembly with an illumination arrangement. The laryngoscope handle includes a plastic hand grip, a plastic end cap, and at least one plastic frangible member for engaging a hand grip and an end cap in a pre-actuated position of an end cap which is broken on application of a relatively minor manual detachment force to the end cap, thereby precluding subsequent use of the laryngoscope handle.
Patent CA-2922958-A1 (CA)
Title: Gene expression biomarkers of laquinimod responsiveness
Inventor: HAYARDENY LIAT
IPC: C12Q1/68
Filed: 2014-09-12
Abstract: This invention provides a method of predicting clinical responsiveness to laquinimod therapy in a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising evaluating expression of a biomarker in the subject. This invention also provides a method of treating said subject comprising determining whether the subject is a laquimmod-responder by evaluating expression of a biomarker. Also provided is laquinimod or a pharmaceutical composition comprising laquinimod for use in treating said subject, and a therapeutic package for use in dispensing to said subject, wherein the subject has been identified as a laquimmod-responder or expression of a biomarker in the subject is up-regulated or suppressed.
Patent CA-2923518-A1 (CA)
Inventor: BUNTING NATHAN
IPC: B60F5/00
Filed: 2016-03-10
Abstract: All-terrain construction vehicles are provided that can include: a central frame; a pair of axles, each of the axles extending substantially normally across an axis of the central frame and pivoting in relation thereto; and at least two pairs of wheels. The vehicles can include at least two pairs of levelers. The vehicles can include out-rigging operatively extending above the one axis and between an operator cab and fluid pump unit in at least one configuration, the pump and fluid therefrom operatively coupled to the axles and wheels, the axles, wheels, and pump being operatively controlled via an operator interface within the operator cab. The vehicle can include levelers along the one side of the axis of the frame configured to support a utility pole above the hydraulic fluid pump unit.
Patent CA-2925172-A1 (CA)
Title: Dispositif formant element mural de construction
Inventor: BOUTRY JEREMIE
IPC: E04B1/04
Filed: 2013-10-23
Abstract: La présente invention concerne un dispositif de construction (1), comprenant au moins un mur intérieur (8) et au moins un mur extérieur (9), caractérisé par le fait que ledit mur intérieur (8) est constitué d'un unique élément, conformé en L de manière à constituer une embase (11) tournée vers l'extérieur, l'extrémité extérieure de ladite embase (11) formant des moyens de réception (12) supportant ledit mur extérieur (9).
Patent CA-2929502-A1 (CA)
Inventor: LUO GUANGLIN
IPC: C07D409/04
Filed: 2014-11-03
Abstract: The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands, antagonists of the NR2B receptor and may be useful for the treatment of various disorders of the central nervous system.
Patent CA-2933811-A1 (CA)
Title: P2x3 and/or p2x2/3 compounds and methods
Inventor: THOMPSON SCOTT
IPC: A61K31/437
Filed: 2014-12-16
Abstract: The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R4 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient.
Patent CA-2934095-A1 (CA)
Inventor: BLOEMKER SHAWN C
IPC: G09B19/00
Filed: 2016-06-23
Abstract: A metal container with a combustible liner for use as a portable firefighting training unit. The combustible liner is formed of particle board sections loosely assembled inside the metal container with an opening in the liner in registry with an access opening in the metal container. The unit may be used to demonstrate various phenomena associated with a developing fire including the flammability of unburned products of combustion, hose stream techniques with a spray bottle filled with water, flashover and backdraft.
Patent CA-2934492-A1 (CA)
Inventor: DESHPANDE PRASAD KESHAV
IPC: A61P31/04
Filed: 2015-01-21
Abstract: L'invention concerne des composés de formule (I), leur préparation et leur utilisation pour la prévention ou le traitement d'une infection bactérienne. (I)
Patent CA-2936891-A1 (CA)
Inventor: FLITSCH FREDERICK A
IPC: H04W4/90
Filed: 2016-07-22
Abstract: Methods and apparatus to form a biometric based information communication system are described. In some examples, the biometric based information communication system comprises biomedical devices with sensing means, wherein the sensing means produces a biometric result.  In some examples the biometric based information communication system may comprise a user device such as a smart phone paired in communication with the biomedical device. A biometric measurement result may trigger a communication of a biometric based message.  The system may operate in a vehicular environment.
Patent CA-2937737-A1 (CA)
Inventor: SASHIN ALEXANDER
IPC: B23C5/24
Filed: 2015-01-27
Abstract: An adjustable insert cutting angle cutting tool has a tool holder with a cartridge receiving pocket and an insert cartridge for retaining a removable cutting insert. The insert cartridge is clamped in the cartridge receiving pocket by a clamping member operated by a separate single fastening member, and the insert cutting angle is adjusted by rotating the insert cartridge about a pivot axis in the tool holder, following release of the fastening member. The insert cartridge has opposing upper and lower surfaces generally facing in upward and downward directions and a peripheral suiface extending therebetween. The peripheral suiface has a non-planar abutment surface which makes contact with a side wall surface of the cartridge receiving pocket. The side wall surface has exactly two spaced apart abutment zones (Azl, Az2), and the abutment suiface makes contact with the two abutment zones (Az 1, Az2) for the insert cutting angle's whole adjustment range.
Patent CA-2938592-A1 (CA)
Inventor: APPLEMAN JAMES
IPC: A61K31/4418
Filed: 2015-02-07
Abstract: The present disclosure relates to methods for treating or preventing a fibrotic disorder or disease, wherein differentially expressed genes in subjects with said fibrotic disorder or disease are target for therapy using gene or protein modulators.
Patent CA-2938699-A1 (CA)
Inventor: VAKA SIVA RAM KIRAN
IPC: A61K9/00
Filed: 2015-02-05
Abstract: Disclosed are solid oral pharmaceutical compositions that that are intended to provide protection against overdose and tampering, as well as abuse deterrence. The compositions contain a plurality of granules or multi-particulates. A first population of multi particulates contains an API or drug susceptible to abuse, a polymer matrix, and an outer coating that contains a cationic pH dependent polymer. These multi particulates also contain a plasticizer and a surfactant. A second population of multi particulates contains a viscosity building polymer and an alkaline buffering agent. Compositions may further include a disintegrant, and/or additional viscosity building polymers and/or alkaline buffering agents and/or ion exchange polymers. Also disclosed are the methods of making and using the compositions.
Patent CA-2940824-A1 (CA)
Inventor: JUNGWIRTH DOUGLAS R
IPC: G01S7/481
Filed: 2016-08-31
Abstract: A method and apparatus for scanning a target region. A divergence of a laser beam during scanning of the target region is set. The laser beam is directed to different locations in the target region at a scan angle. The scan angle of the laser beam is set while the laser beam is directed to the different locations. Changing at least one of the divergence or an amount of change in the scan angle during scanning of the target region changes a resolution for the target region.