baber/WOPTO huggingface dataset:
Patent PT-1885695-E (PT)
Title: Indoline compounds
Inventor: LEBRETON LUC
IPC: A61K31/404
Filed: 2006-05-29
Abstract: Sulfonylindoline compounds (I) and their salts are new. Sulfonylindoline compounds of formula (I) and their salts are new. R 1 : H, halo, 1-4C alkyl, 3-4C cycloalkyl, 1-3C alkoxy, CF 3or OCF 3; R 2 : H or halo; R 3 : H or CF 3; R 4 : H or 1-3C alkoxy; Y 1 : 1-8C alkylene (optionally substituted by phenyl), a partially cyclized moiety or -(CH 2) n-W 1; W 1 : O or S; n : 2-4; Z : 1-4C alkyl, 3-4C cycloalkyl, CF 3, COR a, (hetero)aryl or heterocyclic e.g. phenyl, pyrrolidinyl, pyrrolidinylone, imidazolyl, pyridinyl, piperidinyl, piperazinyl or morpholinyl (all optionally substituted by 1-2 of halo, 1-4C alkyl, 3-4C cycloalkyl, 1-4C alkoxy, CF 3, nitro, N(R) 2, -CH 2-N(R) 2, OH, CN or -X-(C(R) 2) p-COR a); X : bond, O, S or NH; R a : OR or N(R) 2; R : H or 1-4C alkyl; and p : 0-4. Provided that simultaneously, R 1and R 3are not hydrogen. An independent claim is also included for the preparation of (I). [Image] ACTIVITY : Neuroprotective; Cardiovascular-Gen.; Antiinflammatory; Antilipemic; Anorectic; Antidiabetic. MECHANISM OF ACTION : Liver X receptor modulator. The ability of (I) to transactivate Gal4-liver X receptor after the transitory transfection in COS7 cells was tested. The results showed that (I) exhibited an EC 50value of less than 1 mu M.
Patent PT-2054669-E (PT)
Title: Burner with a protective element for ignition electrodes
Inventor: BOETTCHER ANDREAS
IPC: F23Q3/00
Filed: 2007-08-14
Abstract: The burner (2) for gas turbines has a protective sleeve (8) over its ignition electrode (7). The sleeve has a U-shaped cross-section.
Patent PT-668769-E (PT)
Inventor: HON DAVID N S
IPC: A61K33/24
Filed: 1993-11-04
Abstract: Higher concentrations of oak bark ash extract, i.e., greater than 20% by weight, are useful for the treatment of skin cancers. Lower concentrations of oak bark extract possess additional therapeutic properties not heretofore recognized. For example, preparations containing 40-80% oak bark extract are useful in the treatment of acute cancerous skin ulcers. In addition, synthetic mixtures containing potassium ions, zinc ions, calcium ions provide many of the same advantageous properties of oak bark extract. The inclusion of rubidium ions and sulfur is also advantageous for some applications.
Patent PT-877132-E (PT)
Title: Device for manually controlled handles
Inventor: AVVANZINI UGO
IPC: E05B63/18
Filed: 1998-05-08
Abstract: A device (1) for manually controlling handles, of the type comprising a body (2) for the containment of motion transmission means able to be inserted in a chamber with longitudinal development presented by a section bar of a movable frame; the device (1) presents on the containment body (2) means able to allow the association of a handle to the section bar, means comprising at least one pair of seats (7) distanced from each other by a value (H7) ranging from 22 and 30 mm. <IMAGE>
Patent PT-981381-E (PT)
Title: Polyhydroxyalkanoates for in vivo applications
Inventor: WILLIAMS SIMON F
IPC: C08G63/91
Filed: 1998-05-12
Abstract: Polyhydroxyalkanoates (PHAs) from which pyrogen has been removed are provided. PHAs which have been chemically modified to enhance physical and/or chemical properties, for targeting or to modify biodegradability or clearance by the reticuloendothelial system (RES), are described. Methods for depyrogenating PHA polymers prepared by bacterial fermentation processes are also provided, wherein pyrogens are removed from the polymers without adversely impacting the polymers' inherent chemical structures and physical properties. PHAs with advantageous processing characteristics, including low melting points and/or solubility in non-toxic solvents, are also described. The PHAs are suitable for use in in vivo applications such as in tissue coatings, stents, sutures, tubing, bone, other prostheses, bone or tissue cements, tissue regeneration devices, wound dressings, drug delivery, and for diagnostic and prophylactic uses.
Patent PT-955476-E (PT)
Inventor: ALBERT FRISCHMANN
IPC: F16B13/14
Filed: 1999-04-29
Abstract: The drilled hole(6) is filled with a hardening substance(5) so that after hardening of the substance the threads(4) of the screw(1) are embedded partially in the solid material(17) and partially in the mortar shell(13). The depth of penetration of the thread in the solid material is 30-50 per cent of the thread depth. The penetration depth of the screw is 5 to 10 times the screw's diameter. At the leading end of the screw shank(2) there is at least one slot(19) extending in the longitudinal direction.
Patent PT-1084080-E (PT)
Inventor: BOLTON JAMES R
IPC: C02F1/32
Filed: 1999-05-05
Abstract: A method for prevention of cryptosporidium oocysts and similar organisms in water by irradiating the water with ultraviolet light in a range of 200 to 300 nm in doses of about 10 mJ/cm2 to 175 mJ/cm2.
Patent PT-1082724-E (PT)
Inventor: KALCHER CONNY
IPC: G11B33/04
Filed: 1999-05-27
Abstract: A box for storing a storage medium, comprising two parallel walls. A first one of the walls has an outer surface with protruding studs, and a second wall has an outer surface with cavities for receiving the studs on another similar box. The studs and cavities are provided in respective rows allowing two or more boxes to be stacked either aligned or shifted, and a row of several boxes shifted relative to each other is self supported and can stand on a tabletop without any support.
Patent PT-1060520-E (PT)
Title: Frame made of shaped sections and designed for plate-like elements, and array of several such frames
Inventor: TOGGWEILER PETER
IPC: H02S30/10
Filed: 1999-07-01
Abstract: The invention relates to a frame made of shaped sections which preferably has a rectangular or square shape and is designed to receive plate-like elements having a front, a back and sides. At least one of the shaped sections has an L-shaped part so as to support the plate-like element at the back and hold it at the sides. Said shaped section can also present only one supporting surface so as to support the plate-like element only at the back. The other shaped sections comprise a first U-shaped part which is open towards the plate-like element and receives the edge area of said plate-like element. At least one of the shaped sections having a U-shaped part comprises a second U-shaped part which is open to the front or back. The array of plates and frames made of shaped sections provided for by the invention makes it possible, among other things, to use such arrays as roof elements.
Patent PT-1094791-E (PT)
Inventor: GOUTAY ERIC
IPC: A61K9/48
Filed: 1999-07-05
Abstract: The invention concerns liquid or pasty thixotropic compositions containing an active substance for filling capsules at room temperature. The compositions become fluid by the effect of shearing when they pass through the filling nozzle, then recover their consistency with sufficient intensity and rapidity to prevent, after filling any leak between the two capsule parts. Said compositions are characterized in that their rheological properties are specially adapted for filling and for optimal recovery of consistency. They are preferably in the form of dispersions supporting amphiphilic excipients. Said compositions enable the formulation of active liquid, pasty and even solid substances.
Patent PT-1107793-E (PT)
Inventor: LITZINGER DAVID C
IPC: A61K47/48
Filed: 1999-08-10
Abstract: The present invention relates to dextran-leptin conjugate compositions, and related methods of preparation, methods of use, and pharmaceutical compositions.
Patent PT-1128916-E (PT)
Inventor: WELSER WOLFGANG
IPC: B23K26/08
Filed: 1999-11-15
Abstract: Previous methods for producing a profile section with varying wall thicknesses such as extrusion moulding, extrusion drawing or rolling are expensive and do not meet modern requirements in terms of dimensional accuracy. The objective of the invention is to provide a low-cost method for the production of profile sections with varying wall thicknesses, while guaranteeing dimensional accuracy. Strips are used as a starting material. Said strips are continuously fed into a welding installation and welded to each other on a longitudinal edge before being formed in a forming device. This enables profile sections with varying wall thicknesses to be produced at low cost and in a quick manner by using strips with the appropriate wall thicknesses. By simply changing the strips it is possible to produce different profile sections with low set-up times. The dimensional accuracy provided by the method is primarily directed towards the dimensional accuracy of strips that are used as a starting material. The inventive method is particularly suitable for strips that are made of aluminium, for instance, or steel with a wall thickness of up to 30 mm.
Patent PT-1153032-E (PT)
Inventor: RAZAVI ABBAS
IPC: C08F4/44
Filed: 1999-12-13
Abstract: A metallocene compound having the general formula: CpAXMQ1Q2Cp'A'X'M'Q1'Q2' wherein Cp and Cp' are each independently a substituted or unsubstituted cyclopentadienyl moiety; M and M' are each independently a metal chosen from Group IV B transition metals and vanadium, and coordinate to Cp and Cp' respectively; X and X' are each independently a substituted or unsubstituted Group VA or VIA heteroatom and coordinate to M and M' respectively; A and A' are bridging groups between Cp and X and between Cp' and X' respectively and are independently chosen from -SiR'2-O-SiR'2-, -SinR'm-, -CnR'm- and -CR'2-SiR'2-CR'2-SiR'2-, in which each R'is independently H or hydrocarbyl having 1 to 20 carbon atoms, n is an integer in the range 1 to 4 and m=2n; each Q1, Q2 and Q1' and Q2' is independently a coordinating group which is hydrogen, halogen or hydrocarbyl having 1 to 20 carbon atoms and each of Q1 and Q1' is coordinated to both M and M'.
Patent CA-2607375-F (CA)
Title: Method for the purification of antibodies
Inventor: FALKENSTEIN ROBERTO
IPC: C07K1/18
Filed: 2006-05-23
Granted: 2006-11-30
Abstract: A method for the purification of immunoglobulins by ion exchange chromatography is described. The chromatographic method uses a weak ion exchange resin and a single step elution process for the purification of an immunoglobulin. Additionally a method for the determination of the salt concentration for the single step elution of an immunoglobulin from an ion exchange resin is described.
Patent SG-28351-G (SG)
Title: Method for transmitting a digital signal
Inventor: SCHOLZ WERNER DIPL-ING
IPC: H04L7/08
Filed: 1988-11-02
Abstract: In transmission, in particular recording, synchronisation information comprising a synchronisation word and an additional item of information are transmitted. A simple and reliable evaluation is to be created for both items of information. The synchronisation word at the same time contains the item of additional information and the synchronisation pattern (S). The synchronisation pattern (S) and the item of additional information are obtained by a different demodulation of the synchronisation word.   In particular for the recording of a digital signal. <IMAGE>
Patent IE-34054-L (IE)
Title: Foodstuff container
IPC: A47G19/26
Filed: 1970-03-11
Abstract: This invention is primarily directed to a supporting container or base for butter or the like that includes a recessed surface portion surrounded by a peripheral outwardly extending ledge and outside sealing surface adapted to mate with a cover having peripheral dimensions suitable to produce tapered fit between the two mating surfaces.
[US3709397A]
Patent IE-850325-L (IE)
Title: COMPLEXATION OF N-2-PYRIDYL-2H-1,2-BENZOTHIAZINE-3-CARBOXA¹MIDE,1,1-DIOXIDE WITH Ó,ß OR Ô-TYPE CYCLODEXTRINS
IPC: A61K31/54
Filed: 1985-02-11
Abstract: New inclusion compounds of 4-hydroxy-2-methyl-N-2-pyridyi-2H-1,2-benzothiazine-3-carboxyamide-1,1-dioxide with α, β or γ cyclodextrins, obtained by reaction of said cydodextrins and said 4-hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxyamide-1,1-dioxide in aqueous or water/organic solutions are described. The ratio between 4-hydroxy-2-methyl-N-2-pyridyil-2H-1,2-benzothiazine-1,1-dioxide and the cyclodextrins is comprised between 1:10 and 1:1; preferably, it is about 1:2.5.The compounds of the invention possess high antiinflammatory and analgesic activities, together with a considerably reduced gastrolesive action.
Patent IE-36260-L (IE)
Title: Steroidal silyl ethers
IPC: C07J1/00
Filed: 1972-04-06
Abstract: 1367735 Silyl ethers of 11-alkyl-3-hydroxyestratrienes G D SEARLE & CO 6 April 1972 [7 April 1971] 15838/72 Heading C2U [Also in Division A5] Novel steroids of the formula (wherein R is H or a trialkylsilyl radical; R<SP>1</SP> is a C 1-3 alkyl radical; and the alkynyl radical contains 2-7 carbon atoms) are prepared (i) when R is trialkylsilyl, by silylating the compounds wherein R is H or corresponding 3-ols, the compounds wherein R is H being in turn prepared by alkynylation of the corresponding 17-ones or by silylation in the 3-position only of corresponding 3-ols. Starting materials of the formula are prepared by silylation of the corresponding 3-ols. 11# - Ethyl - 17α - ethynylestra - 1,3,5(10)- triene - 3,17# - diol is prepared by oxidizing 3 - benzyloxy - 11 - hydroxy - estra - 1,3,5(10)- trien - 17 - one 17 - ethylene ketal (prepared by benzylation of the corresponding 3,11-diol) to the corresponding 11-one, reacting this with C 2 H 5 MgBr to give the corresponding 11#-ethyl- 11α-ol, refluxing this with concentrated hydrochloric acid in ethanol to give 3-benzyloxy- 11 - ethylestra - 1,3,5(10),9(11) - tetraen - 17- one, hydrogenating this to 11#-ethyl-3-hydroxyestra - 1,3,5(10) - trien - 17 - one and alkynylating this. 17α-Ethynyl-11#-(n-propyl)estra-1,3,5- (10) - triene - 3,17# - diol is prepared by reacting 3 - benzyloxy - 17# - hydroxy - estra - 1,3,5(10)- trien - 11 - one (prepared by benzylation of the 3,17 - diol) with allyl magnesium bromide to give 11 - allyl - 3 - benzyloxyestra - 1,3,5(10)- trien - 11,17# - diol, treating this with formic acid to give 11-allyl-3-benzyloxyestra-1,3,5(10),9- (11) - tetraen - 17# - ol 17 - formate, oxidizing this to the corresponding 17-one, hydrogenating this to 3 - hydroxy - 11# - (n - propyl) - estra- 1,3,5(10)-trien-17-one and ethynylating this. The novel steroids have use as chemosterilants for the control of nuisance animal populations, for which purpose they are conveniently incorporated in a bait containing an edible carrier. They may also be made up into pharmaceutical compositions with suitable carriers and used for their estrogenic, anti-fertility and pituitary inhibitory properties.
[GB1367735A]
Patent IE-42710-L (IE)
Title: Piperazine derivative
IPC: A61K31/495
Filed: 1976-03-05
Abstract: The invention provides a new piperazine derivative, 1-(4-fluoro-3-trifluoromethylthio-phenyl)-piperazine of the formula <IMAGE> and its pharmaceutically acceptable acid addition salts, which is useful as a medicament in human and veterinary therapy because of its anorexia-inducing effect.
[US4044132A]
Patent IE-31893-L (IE)
Title: Evaporators, sugar crystallization
IPC: C13B30/02
Filed: 1968-04-29
Abstract: 1,203,143. Evaporators; crystallization of sugar. ATELIERS BELGES REUNIS S.A. 30 April, 1968 [2 May, 1967], No: 20517/68. Heading B1B. An evaporator for producing uniform crystals from a solution, e.g. of sugar, comprises an elongated, generally horizontal chamber 1 which has a downwardly-inclined bottom and increases progressively in cross-sectional area from end A to end B, and is provided with a heat exchanger 12 formed by a series of vertical transverse walls connected in pairs by vertical longitudinal walls of relatively small width, the area of heating surface per unit length of chamber increasing from end A to end B. The interior of the heat exchanger is supplied with steam from source V. Sugar solution is introduced into chamber 1 through tubes 3 1 .. 3 7 and seed crystals are supplied through tube 5. A suspension of crystals in boiling solution ascends the vertical passages 18 through the heat exchanger on one side of the chamber, and the solution descends on the other side, so that the suspension advances in a helicoidal path from end A to end B. The grown crystals suspended in solution are discharged through conduit 7. Vapours are discharged through orifice 19, which may be connected to a condenser and vacuum pump. The sugar solution may be boiled at a temperature of 70‹C. In a modified evaporator, the chamber I is divided into compartments by transverse partitions having openings, and the steam chamber of the heat exchanger is divided into two sections each connected to the steam source by a separate valve-controlled line. The bottom of the evaporator chamber and the side near which ascending movement of the suspension occurs are provided with a heating jacket.
[GB1203143A]
Patent IE-40945-L (IE)
Title: Benzomorphane derivatives.
IPC: A61K31/341
Filed: 1975-03-07
Abstract: Novel 2-tetrahydrofurfuryl-6-7-benzomorphans of the accompanying formula I, in which R<1> denotes methyl, ethyl or propyl; R<2> denotes hydrogen, methyl or ethyl; R<3> denotes hydrogen or methyl; and R<4> denotes hydrogen, alkyl having 1 to 4 carbon atoms or acyl having 2 to 5 carbon atoms, are prepared by introducing the tetrahydrofurfuryl radical into appropriately substituted norbenzomorphans by the methods of N-alkylation. The resulting bases of the formula I can then be converted into their acid addition salts. The compounds of the formula I and their acid addition salts are distinguished by a therapeutically utilisable action on the central nervous system. Particularly to be emphasised is their analgesic action, which frequently exceeds that of morphine, without exhibiting the undesired side effects of morphine, e.g. the addictive action. <IMAGE>
[GB1496418A]
Patent IE-830531-L (IE)
Title: Enzyme-antibody conjugates associated by covalent bond
IPC: A61K39/44
Filed: 1983-03-11
Abstract: The present invention relates to new immunoenzymic conjugates resulting from a chemical coupling, by covalent bond, of an antibody or a fragment of antibody, which has retained the capacity of recognizing the selected antigen, with an enzyme capable of producing ammonium ions from natural substrates which are well tolerated in higher animal organisms. The invention also relates to a process for the preparation of these conjugates and the medicinal associations of said conjugates with an immunotoxin.
Patent IE-780651-L (IE)
Title: Device for controlling gas flow into vessels
IPC: F17C5/06
Filed: 1978-04-03
Abstract: Device for controlling gas flow into vessels without allowing undesired gas, such as outside air, from entering the vessel.
[US4131129A]
Patent IE-810960-L (IE)
Title: Push-button for switch
IPC: H01H13/705
Filed: 1981-04-29
Abstract: A push-button for use, for instance, on a telephone keypad, consists of a rectangular pad 7 of an insulating material in a cut out in a supporting frame 1,2 of the same material and coupled along one edge by an integral hinge 8 of reduced thickness, the pad being additionally supported by a pair of integral arms 11 extending between the end of the actuating portion 9 and the frame. As used in a telephone keypad the push-buttons are made in an integral one piece structure (20), which is fitted in the telephone with each push-button head (21) projecting through a hole in a cover plate (22). Below the structure 20 there is a dimple pad (23) with a dimple switch per push-button. The resilience of the button material plus the resilience of the dimple causes button restoration. <IMAGE>
[GB2084802A]
Patent IE-840998-L (IE)
Title: Carbostyril derivatives
IPC: C07D215/32
Filed: 1984-04-25
Abstract: A group of 5-(2-aminoethyl)-8- hydroxycarbostyril derivatives was prepared by deprotecting certain 8-alkoxy or benzyloxycarbostyrils. 5-[N-n- Propyl-N- (p-hydroxy-phenethyl)-2-aminoethyl] -8- hydroxycarbostyril has excellent presynaptic dopamine agonist activity.
Patent FI-853742-L (FI)
Inventor: LARSSON LARS ERIK
IPC: E21B17/00
Filed: 1985-09-27
Abstract: A drill steel (10) for percussion drilling has four longitudinally extending grooves (13) for removal of cuttings. The grooves (13) are shaped such that, in comparison with a hexagonal drill steel, there is obtained an enlarged space for cuttings and a less consumption of material with maintenance of the same resistance to bending.
Patent IE-41072-L (IE)
Title: Pesticide formulation
IPC: A01N25/14
Filed: 1975-05-28
Abstract: A user-friendly pesticidal composition with improved stability is prepared. The active ingredient and the carrier can be selected as desired. First, an intimate mixture of the pesticidal active substance, at least one surfactant and a liquid medium capable of sublimation are frozen. Then, the pressure above the frozen mixture is lowered below the triple point pressure of the liquid medium, and the medium is removed in the form of a gas. The pressure is kept below the pressure at which the medium can be in liquid form.
[GB1511834A]
Patent IE-821361-L (IE)
Title: Diamionic 5, 5'-azobis-salicylic acid composition
IPC: A61K47/48
Filed: 1982-06-08
Abstract: The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid.
[US4374932A]
Patent IE-861427-L (IE)
Title: Making drill bit blank
IPC: B23B51/00
Filed: 1986-05-29
Abstract: A plurality of blanks for drill bits are produced from a disc-shaped composite abrasive compact by first producing a plurality of sticks of polygonal shape end-on and thereafter longitudinally rounding each stick. The rounded drill blank is then fluted to produce a small diameter twist drill bit.
[US4694710A]
Patent IE-37012-L (IE)
Title: Detergent compositions containing enzymes
IPC: C11D1/14
Filed: 1972-12-14
Abstract: Enzyme-contg. washing and cleaning agent mixt. contains (A) 0.001-5 wt. % (w.r.t. total mixt.) of an enzyme, esp. 0.1-2 wt. % of a proteolytic enzyme, which when used as a 1% soln. of a cmpsn. similar to that of the invention, but in which all of anionic and cationic active ingredients are replaced by nonionic surfactants, gives a better cleaning effect than when used under the same conditions in a cmpsn. modified by replacement of the cationic active ingredients by anionic surfactants, and (B) 2-50 (5-30) wt. % surfactant mixt. consisting of (b) 10-19 (20-80) wt. % of a cationic surfactant and (c) 90-10 (80-20) wt. % of an anionic surfactant, where the relative amounts of (b) and (c) are expressed w.r.t. (b) + (c). Better cleaning power, esp. spot removal and some softening of textile may be achieved, depending on cationic component and cationic/anionic component ratio.
[BE792982A2]
Patent IE-891888-L (IE)
Title: Compressable ball launcher
IPC: A63B65/12
Filed: 1989-06-13
Abstract: A launcher for a soft compressible closed cell foam ball (30) which includes a cavity in which the ball (30) is forced into from the front of the barrel (20) and is held loosely therein and a plunger (23) coupled to the barrel (20) for causing the ball to be compressed and then spring out of the cavity accompanied by a loud popping sound.
Patent IE-41807-L (IE)
Title: Biguanide salts
IPC: C07C239/00
Filed: 1975-10-06
Abstract: Biguanide salts of the formula <IMAGE> I wherein R1, R2, R3 and n are as hereinafter set forth, are described. The aforementioned biguanides are useful as hypoglycemic agents.
[US4028402A]