baber/WOPTO huggingface dataset:
Patent NZ-290388-A (NZ)
Title: Use of heterocyclic compounds as dopamines-D3 ligands
Inventor: HELLENDAHL BEATE
IPC: A61K31/33
Filed: 1995-07-14
Abstract: Use of a compound of the formula Het-A-B-Ar and the salts thereof with physiologically tolerated acids, in the manufacture of a medicament for treating disorders that respond to dopamine D3 receptor antagonists, wherein: A is a straight or branched alkylene group which contains at least one group which is selected from among O, S, NR4, CONR4, NR4 CO, COO, and OCO; B is a radical of formulae (I); Ar is a phenyl, pyridyl, pyrimidyl or triazinyl, where Ar may have one to four substituents selected from the group consisting of OR4, alkyl, alkenyl, alkynyl, halogen, CN, CO2R4, NO2, SO2R4, SO3R4, NR4R5, SO2NR4R5, SR4, CF3, CHF2, a 5- or a 6-membered carbocyclic, aromatic or non-aromatic ring and a 5- or a 6-membered heterocyclic, aromatic or non-aromatic ring having 1 to 3 hetero atoms which are selected from O, S and N, where the carbocyclic or the heterocyclic ring is unsubstituted or substituted by alkyl, halogen, O-alkyl, OH, NO2 or CF3, and where Ar may also be fused to a 5- or 6-membered carbocyclic, aromatic ring or to a 5- or 6-membered heterocyclic, aromatic or non-aromatic ring having 1 to 3 heteroatoms which are selected from O, S and N, where the carbocyclic or the heterocyclic ring is unsubstituted or substituted by -alkyl, halogen, O-alkyl, OH, NO2 or CF3; Het is a group of formulae (II); R1, R2 and R3 are, independently of one another, H, halogen, OR5, NR4R5, SR4, CF3, CN or alkyl which is unsubstituted or substituted by OH, O-alkyl or halogen; R4 is H or alkyl unsubstituted or substituted by OH, O-alkyl or halogen; R5 is the meaning indicated for R4 or is COR4 or CO2R4.
Patent NZ-302042-A (NZ)
Title: Force sensing assembly for tabbing means of article destacker
Inventor: BACCO DAVID
IPC: B31B50/06
Filed: 1996-01-23
Abstract: A force sensing assembly measures a magnitude of a force generated at the tabs in a product delivery system. The product delivery system can be one in which a force is produced at the tabs by the weight of the stack, by a paddle pushing an end of the stack, or by another similar type of advancing mechanism. In a preferred embodiment, the force sensing assembly has a pair of tabs connected to a cross-bar which extends across the stack and which is connected to the frame of the feeder through a bell crank at one end and a lever at the other end. The bell crank has one arm connected to the cross-bar and a second arm connected to a load cell. The force at the tabs causes the lever and bell crank to rotate, with the force being transmitted through the bell crank, through a spring, and then to the load cell. The load cell generates a force signal which is supplied to a controller for adjusting the amount of force at the tabs. The controller adjusts the force by adding more products to the stack or by advancing the stack closer to the tabs. The load cell preferably has a stopper for preventing an excessive amount of force from reaching the cell.
Patent NZ-328283-A (NZ)
Title: Window stay able to be readily removed from a window frame
Inventor: FIGLIOLA UMBERTO
IPC: E05D7/12
Filed: 1998-07-08
Abstract: Window stay 10 is detachably engaged to mounting bracket 11.
Patent NZ-337780-A (NZ)
Title: Liquid nutritional formula containing hydrolysed protein and a fiber blend for management of infant diarrhea, colic and other maladies
Inventor: BERK DAVID F
IPC: A23L1/308
Filed: 1998-03-12
Abstract: A liquid nutritional formula which contain hydrolysed protein and/or amino acids and dietary fiber. The formula described overcomes the problems of product physical stability and high viscosities through the use of soluble/non-fermentable fibers in combination with a blend of insoluble/non-fermentable and soluble/fermentable fibers. The formula is directed to the use of physiologically effective levels of fibers in nutritional products that use hydrolysed protein and/or free amino acids for the source of amino nitrogen to treat colic, diarrhoea, short gut syndrome and other gastrointestinal maladies.
Patent NZ-500252-A (NZ)
Title: 6-(4-Methyl-piperazin-1-yl)-1H-indole derivatives useful as 5HT1A, 5HT1B and 5HT1D receptor antagonists
Inventor: WYMAN PAUL ADRIAN
IPC: A61K31/501
Filed: 1998-04-14
Abstract: An indole derivative of formula (I) or a salt thereof is disclosed wherein: Ra is a group of formula (i) or (ii) P1 is phenyl, bicyclic aryl, a 5 to 7 membered heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen and sulphur, or a bicyclic heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen and sulphur; R1 is hydrogen, halogen, alkyl, cycloalkyl, CO-alkyl, alkoxy, hydroxy, hydroxyalkyl, hydroxyalkoxy, alkoxyalkoxy, acyl, nitro, trifluoromethyl, cyano, SR9, SOR9, SO2R9, SO2NR10R11, CO2R10, CONR10R11, CO2NR10R11, CONR10(CH2)cCO2R11, (CH2)cNR10R11, (CH2)cCONR10R11, (CH2)cNR10COR11, (CH2)cCO2alkyl, CO2(CH2)cOR10, NR10R11, NR10CO2R11, NR10CONR10R11, CR10=NOR11, NR10COOR11 CNR10=NOR11; R10 and R11 are independently hydrogen or alkyl; c is 1 to 4; R2 is hydrogen, halogen, alkyl, cycloalkyl, cycloalkenyl, alkoxy, alkanoyl, aryl, acyloxy, hydroxy, nitro, trifluoromethyl, cyano, CO2R10, CONR10R11, NR10R11; a is 1, 2 or 3; P2 and P3 are independently phenyl, bicyclic aryl, a 5- to 7- membered heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen and sulphur, or a bicyclic heterocyclic group containing 1 to 3 heteroatoms selected from oxygen, nitrogen or sulphur; A is a bond or oxygen, S(O)m, carbonyl, CH2, -CH2CH2- or NR4; R4 is hydrogen or alkyl; m is 0 to 2; for formula (ii) R1 can also be an optionally substituted 5 to 7-membered heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen or sulphur; R2 and R3 are independently hydrogen, halogen, alkyl, cycloalkyl, cycloalkenyl, alkoxy, alkanoyl, aryl, acyloxy, hydroxy, nitro, trifluoromethyl, cyano, CO2R10, CONR10R11, NR10R11; b is 1, 2 or 3; Y is -NH-, -NR5-,  -CH2- or -O-; R5 is alkyl; V is oxygen or sulphur; D is nitrogen, carbon or a CH group; W is (CR16R17)t or (CR16R17)u-J t is 2, 3 or 4; R16 and R17 are independently hydrogen or alkyl; u is 0, 1, 2 or 3; J is oxygen, sulphur, CR16=CR17, CR16=N, =CR16O, =CR16S or =CR16-NR17; X is nitrogen or carbon; Rb is hydrogen, halogen, hydroxy, alkyl, trifluoromethyl, alkoxy, alkenyl, cycloalkyl optionally substituted by alkyl, or aryl; Re is hydrogen or alkyl; the dotted line is a single bond when X is nitrogen or a single or double bond when X is carbon. A pharmaceutical composition thereof is useful for treating CNS disorders.
Patent NZ-500429-A (NZ)
Title: Methods for using macrocyclic lactone compounds such as milbemycin and avermectin in combination with chemotherapeutic agents in tumor and other cells
Inventor: PRICHARD ROGER K
IPC: A61K45/06
Filed: 1998-04-29
Abstract: Described are methods for increasing the toxicity of a cytostatic hydrophobic chemotherapeutic agent against resistant tumor cells by administering a multidrug resistant reversing agent.  The multidrug resistant reversing agent is a macrocyclic lactone compound. Examples of the macrocyclic lactone compounds include the LL-F28249 alpha - lambda series of compounds, the 23-oxo or 23-imino derivative thereof, the avermectins, the 22,23-dihydro derivatives thereof and the milbemycins. Compositions comprising the macrocyclic lactone compounds and the chemotherapeutic agents are also described herein.
Patent NZ-501156-A (NZ)
Title: Azole compounds having a cyclic diamine structure and their use in treating high cholesterol related diseases
Inventor: HIRATA MITSUTERU
IPC: C07D277/74
Filed: 1998-05-26
Abstract: Compounds of formula (I) are inhibitors of acyl coenzyme A cholesterol acyltransferase (ACAT) and may be used for treating hyperlipemia, arteriosclerosis, cerebrovascular disorder, ischemic cardiopathy, ischemic entheropathy or aortic aneurysm. In formula (I); A is an optionally substituted divalent residue of benzene, pyridine, cyclohexane or naphthalene or is a vinylene group; Ar is an optionally substituted aryl group; X is -NH-, oxygen or sulfur; Y is -NR1-, oxygen, sulfur, sulfoxide or sulfone; Z is a single bond or -NR2-; R1 is hydrogen, optionally substituted C1-8alkyl group, optionally substituted aryl group or optionally substituted silyl C1-8alkyl; R2 is hydrogen, optionally substituted C1-8alkyl group, optionally substituted aryl group or optionally substituted silyl C1-8alkyl group; l is an integer of from 0 to 15; m is an integer of 2 or 3; and n is an integer of from 0 to 3.
Patent NZ-513370-A (NZ)
Title: 3-Phenylpyridine derivatives and their use as NK-1 receptor antagonists
Inventor: BOES MICHAEL
IPC: C07D401/04
Filed: 2000-02-15
Abstract: The invention relates to compounds of formula (I) wherein R is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; R1 is hydrogen or halogen; or R and R1 may be together -CH=CH-CH=CH-; R2 is hydrogen, halogen, trifluoromethyl, lower alkoxy or cyano; R3 is hydrogen, lower alkyl or form a cycloalkyl group; R4 is hydrogen, - N(R5)2, -N(R5)S(O)2-lower alkyl, -N(R5)C(O)R5 or a cyclic tertiary amine of the group (a); R5 is, independently from each other, hydrogen, C3-6-cycloalkyl, benzyl or lower alkyl; R6 is hydrogen, hydroxy, lower alkyl, -N(R5)CO-lower alkyl, hydroxy-lower alkyl, cyano, -CHO or a 5- or 6 membered heterocyclic group, optionally bonded via an alkylene group, X is -C(O)N(R5)-, -(CH2)mO-, -(CH2)mN(R5)-, -N(R5)C(O)-, or -N(R5)(CH2)m-; n is 0-4; and m is 1 or 2; and to pharmaceutically acceptable acid addition salts thereof. It has been shown that the above-mentioned compounds have a good affinity to the NK-1 receptor.
Patent NZ-514059-A (NZ)
Title: Polymorphic crystalline forms of celecoxib
Inventor: FERRO LEONARD J
IPC: A61K9/26
Filed: 2000-12-01
Abstract: Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory compound of low water solubility in a therapeutically effective amount, wherein the compound is present in the form of solid particles, about 25 % to 100 % by weight of which are smaller than 1 mm. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders and have particular advantages where rapid onset of therapeutic effect is desired. The novel Form I and Form II crystalline forms of celecoxib are described. The crystalline forms have unique chemical and physical properties relative to other solid state forms of celecoxib and are characterized by their powder x-ray diffraction (PXRD) patterns, differential scanning calorimetric (DSC) thermograms, and other physical characterizations.
Patent NZ-514667-A (NZ)
Title: Method for producing phytosterols from reduced quantities of methanol by crystallization
Inventor: MUSHOLT MARKUS
IPC: C11B13/00
Filed: 2000-03-31
Abstract: A process for the recovery of phytosterols from mixtures with fatty acid esters and methanol by crystallization known per se, filtration, washing and drying, wherein methanol is used in quantities of 25 to 75% by weight, based on the sterols and that after crystallization, the crude sterols are washed with fatty acid esters.  Suitable starting materials in this process include the distillation residues obtained, for example, as so-called deodorized condensates in the production of fatty acid methyl esters based on rapeseed oil, sunflower oil or tall pitch oil obtained from birch bark. These phytosterols are suitable for use as food additives.
Patent NZ-515285-A (NZ)
Title: Indole-type derivatives as inhibitors of p38 kinase
Inventor: MAVUNKEL BABU J
IPC: A61K31/395
Filed: 2000-05-19
Abstract: The invention is directed to methods to inhibit p38- alpha kinase using compounds of formula (1), and the pharmaceutically acceptable salts thereof, or a pharmaceutical composition thereof, wherein (a) represents a single or double bond; one Z2 is CA or CR8A and the other is CR1, CR12, NR6 or N wherein each R1, R6 and R8 is independently hydrogen or noninterfering substituent; A is -Wi-COXjY wherein Y is COR2 or an isostere thereof and R2 is hydrogen or a noninterfering substituent, each of W and X is a spacer of 2-6 ANGSTROM , and each of i and j is independently 0 or 1; Z3 is NR7 or O; each R3 is independently a noninterfering substituent; n is 0-3; each of L1 and L2 is a linker; each R4 is independently a noninterfering substituent; m is 0-4; Z1 is CR5 or N wherein R5 is hydrogen or a noninterfering substituent; each of l and k is an integer from 0-2 wherein the sum of l and k is 0-3; Ar is an aryl group substituted with 0-5 noninterfering substituents, wherein two noninterfering substituents can form a fused ring; and the distance between the atom of Ar linked to L2 and the centre of the alpha ring is 4.5-24 ANGSTROM .
Patent NZ-517083-A (NZ)
Title: Lingerie articles produced from cylindrical knitting comprising retaining characteristics
Inventor: QUERQUANT PIERRE-JEAN
IPC: A41C3/12
Filed: 2001-05-30
Abstract: Lingerie articles comprising at least a moulded region to create a retaining and supporting volume of at least a curved part of the human body, made from a tubular knitted fabric (1) formed with a first extensible and thermoformable material, provided with a ribbing (2) which forms one of the edges of the article elastically enclosing the body, the final shape of the article being produced by cuts performed in the tubular knitted fabric from the free end opposite the ribbing.  Each moulded volume region is lined by internal bonding of a least a lining (9) consisting of a second extensible heat-activated material whereof one surface is coated with an adhesive material capable of being heat-activated, the materials of the knitted fabric and of the lining having either thermoformed or elastic percent elongation, and the adhesive having an activating temperature such that they enable deformation induced by hot moulding of the moulded regions to provide them with volume without affecting the heat-bonded linkage, the first (1) and second (9) materials preserving their supporting and retaining capacity after moulding.
Patent NZ-523826-A (NZ)
Title: System and method for integrating public and private data
Inventor: STEITZ PHILIP W
IPC: G06F21/33
Filed: 2001-06-28
Abstract: A system for delivering integrated data available from a public data store and a private data store to a user system over a network comprises a web server configured to communicate with the user system via the network and an application server in communicate with the web server. The application server comprises at least one aggregation utility configured to receive and integrate data from the public and private data stores and an interactive presentation utility configured to format data from the at least one aggregation utility and to provide the integrated data to the web server for transmittal to the user system.
Patent NZ-526665-A (NZ)
Title: Seeding apparatus utilising concave disc mounted on swinging arm
Inventor: EXLER SELWYN VESEY STEWART
IPC: A01C5/06
Filed: 2003-06-23
Abstract: A seed depositing assembly 6/6' for use in a seeder, a seeder which uses multiple assemblies 6/6' and a kit for retrofitting existing seeders to use the assembly are disclosed. The assembly includes a concave cutting disc attached to a mount 7/7' linked to a swinging arm 8/8'. Each swinging arm 8/8' can move up and down but is forced downwards by a compression spring in place on guide rod 10/10'. Seed hopper 3 supplies seed to the assemblies through tubes 5. The use of the concave disc means that each seed depositing assembly 6/6' can be closely spaced to adjoining assemblies by having its bearing mounted within the concavity.
Patent NZ-527698-A (NZ)
Title: Fencing post or standard
Inventor: KAHN GEORGE S I
IPC: E04H17/08
Filed: 2003-08-19
Abstract: A fence standard comprising or including a member or assembly defining ground penetrating means and an up stand there from, a sleeve or winding of a non conductive material supported about at least part of said up stand, and as a conductive surround, an electrically conductive wrapping, winding or spring form supported about at least part of the sleeve, wherein the sleeve alone or the sleeve together with the up stand defines a region adapted to support a fence wire or the equivalent in electrical contact with said conductive surround thereby to energize the conductive surround from the wire in use.
Patent NZ-535937-A (NZ)
Title: Assaying for H,K-ATPase antibodies, H. pylori antibodies and pepsinogen I concentration for diagnosing the presence of possible gastritis
Inventor: MARDH SVEN
IPC: G01N33/68
Filed: 2003-03-21
Abstract: Described is a method for diagnosing possible presence of gastritis in a human by evaluating a blood sample. The method comprising assaying the blood sample for the presence of antibodies specific for H,K-ATPase, antibodies specific for Helicobacter pylori, and the concentration of pepsinogen I, whereby the presence of H,K-ATPase antibodies, Helicobacter pylori antibodies, and pepsinogen I concentration are compared between themselves and in relation to the respective values of H,K-ATPase antibodies, Helicobacter pylori antibodies, and pepsinogen concentration of a normal population, in a software related system. In this system, altered levels in the sample is indicative of gastritis, and whereby an altered level detection leads to the issuance of a remittance for further investigation with regard to gastritis.
Patent NZ-536430-A (NZ)
Title: Netting and fencing machine
Inventor: BERTUCH GRAEME
IPC: B65H16/00
Filed: 2004-11-08
Abstract: A netting and fencing machine comprising: a frame mountable to a vehicle by way of a bracket attached to the frame, the frame having a longitudinal upright member with an upper arm and a lower arm extending perpendicularly outward from the longitudinal member, each arm being provided with a rotary support and at least one rotary support is driven to rotate such that a spindle for netting or fencing material can be securely clamped between the supports and rotated to dispense or take up material; and a biased tension arm extending from the frame and around which material extends to facilitate in material retrieval.
Patent NZ-538408-A (NZ)
Title: A hot beverage making machine relying on heat from an internal combustion engine
Inventor: SHILLINGTON RORY BRENDAN
IPC: A47J31/00
Filed: 2005-02-23
Abstract: A hot beverage making machine relying on heat from an internal combustion engine (1), the device comprising: a first heat exchange circuit (4) to circulate a working fluid between a heat source (2) and a cold sink wherein the heat source is or is derived from hot combusted gases from the engine and wherein the cold sink is tank retained water (7) to which, in use, heat is transferred from the working fluid to the tank retained water; at least one closable opening to the tank to allow dispensing of fluid from the tank, the at least one opening selected from at least one of (i) an opening (12) to allow the dispensing of hot water vapour and (ii) an opening (10) to allow the dispensing of hot water; a coffee head (17) to retain ground coffee and to allow the passing of drinking water at a temperature above 50 degrees C therethrough for dispensing coffee to a container (18) for subsequent consumption, the drinking water being ducted from a source (15) via a heat exchanging means (14) to elevate the drinking water in temperature from its temperature at the source, the heat exchanging means relying on the heat energy of the engine to elevate the drinking water in temperature.
Patent NZ-540228-A (NZ)
Title: Intervertebral implant comprising joint parts that are mounted to form a universal joint
Inventor: AEBI MAX
IPC: A61F2/46
Filed: 2002-12-17
Abstract: An intervertebral implant (1), in particular an artificial intervertebral disc. The implant comprises a central axis (2), an upper part (10), designed to rest against the lower surface of a vertebral body lying directly above and a lower part (20), designed to rest against the covering surface of a vertebral body lying directly below. The upper part comprises a ventral side face (11), a dorsal side face (12), two lateral side faces (13, 14), an upper apposition face (15) and a lower face (16); the lower part comprises a ventral side face (21), a dorsal side face (22), two lateral side faces (23, 24), a lower apposition face (25) and an upper face (26); and the two parts (10, 20) can be displaced in relation to one another by means of a joint (30) that is situated between the two parts, the joint being a universal joint comprising two rotational axes (3; 4) running transversally to one another.
Patent NZ-540975-A (NZ)
Title: Bottom fish rig
Inventor: BRZOZOWSKI FRANK T
IPC: A01K91/00
Filed: 2005-06-28
Abstract: A bottom fish rig (12) for use in connection with fishing tackle is disclosed. The bottom fish rig has particular utility in connection with fishing tackle having a strong leader with a removable sliding c-weight (25) and a horizontal unilateral three pronged hook that resists snagging and reduces possible injuries. A horizontal unilateral three pronged hook (41) differs from the standard treble hook by having all three barbs (44, 45) oriented upwards in a 180 degree plane and that the horizontal unilateral three pronged hook is designed to lie flat on the surface. To attain this the rig includes an elongated leader having a hook end (14) and a line end (16), with the hook end having a leader hook loop (18) and the leader line end having a leader line loop (20). A split shot is crimped in front of a leader line loop to the leader. A second split shot is crimped to the leader about two-thirds of the length. A sliding c-weight is connected to the leader in this area. The c-weight has a first end having a first bore with an external slot on one side and a second end having a second bore with an external slot on the other side in which the leader is slid into and attached to the sliding weight. At the other end a snap and swivel is attached to the leader hook loop which is used to attach a horizontal unilateral three pronged hook.
Patent NZ-547205-A (NZ)
Title: Intermediates of substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)one derivatives
Inventor: GALLET THIERRY
IPC: A61P17/14
Filed: 2002-09-19
Abstract: 3-ketoesters having structural formula (IV) are disclosed, wherein R1 represents a 2, 3 or 4-pyridine ring optionally substituted by a C3-6 cycloalkyl group, a C1-4 alkyl group, a C1-4 alkoxy group, a benzyl group or a halogen atom, R5 is an halogen atom and R is an ethyl. These 3-ketoesters are used as intermediates in the manufacture of substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-A]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-A]pyrimidin-5(1H)one derivatives.
Patent NZ-551800-A (NZ)
Title: 3-(Heteroaryl-oxy)-2-alkyl-1-aza-bicycloalkyl derivatives as alpha7-nAChR ligands for the treatment of CNS diseases
Inventor: FEUERBACH DOMINIK
IPC: A61K31/439
Filed: 2005-07-13
Abstract: Provided are specified 3-(heteroaryl-oxy)-2-alkyl-1-aza-bicycloalkyl derivatives, wherein the methyl is in the trans-position in relation to the oxygen. The compounds can be used to treat psychotic or neurodegenerative disorders.
Patent NZ-551906-A (NZ)
Title: Lactam tachykinin receptor antagonists
Inventor: FINKE PAUL E
IPC: C07D207/27
Filed: 2005-06-17
Abstract: Disclosed is a compound of formula (I), and pharmaceutically acceptable salts, enantiomers, and diastereoisomers thereof. Also dislcosed is the compound in a medicament which antagonises the effect of Substance P, an undecapeptide, at its receptor site, blocks neurokinin-1 receptors, or treats a disease associated with an excess of tachykinins.