baber/WOPTO huggingface dataset:
Patent NZ-533223-A (NZ)
Title: Anti-il-6 antibodies, compositions, methods and uses
Inventor: GILES-KOMAR JILL
IPC: C07K16/24
Filed: 2002-10-26
Abstract: The present invention relates to at least one novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies derived from the murine CLB-8 antibody, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, methods of making and using thereof, including therapeutic compositions, methods and devices.
Patent NZ-536371-A (NZ)
Title: Process and plant for evaporative concentration and crystallization of viscous lactose-containing aqueous liquid
Inventor: HENNINGFIELD THOMAS DAVID
IPC: C13B30/02
Filed: 2003-03-21
Abstract: Disclosed is a process for evaporative concentration and crystallization of a viscous lactose-containing aqueous liquid, comprising: (a) introducing the lactose-containing aqueous 15 liquid having a dry solids content of 40-75% by weight into a zone and therein subjecting it to the following simultaneous measures: (i) progressive heating at a temperature above 40°C but below the maximum temperature for crystallization of alpha-lactose monohydrate from the liquid; (ii) removal of vapour evaporated from the liquid; and (iii) mechanical agitation able to provide a crystallization promoting decrease of the viscosity of the liquid with crystals formed and suspended therein; to progressively concentrate and simultaneously crystallize the agitated liquid; and (b) recovering the resulting slurry from said zone at a total solids content above 75% for cooling and optional disintegration and further drying.
Patent NZ-541945-A (NZ)
Title: Substituted p-diaminobenzene derivatives
Inventor: KHANZHIN NIKOLAY
IPC: A61K31/381
Filed: 2004-03-18
Abstract: Disclosed are aniline derivatives of formula I, wherein the substituents are as defined in the specification. The compounds are useful for the prevention, treatment and inhibition of disorders and diseases being responsive to opening of the KCNQ family of potassium ion channels, such as epilepsy.
Patent NZ-542495-A (NZ)
Title: 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators
Inventor: OWADA SHINGO
IPC: C07D231/18
Filed: 2004-06-04
Abstract: The present disclosure relates to preventive, therapeutic and improving agents having affinity for and agonistic action on the thrombopoietin receptor for diseases against which activation of the thrombopoietin receptor is effective. Specifically, it relates to pharmaceutical compositions of formula (1), variables of which are described in the specification, comprising compounds which increase platelets through stimulation of differentiation and proliferation of hematopoietic stem cells, megakaryocytic progenitor cells and megakaryocytes or compounds for therapeutic angiogenesis or with anti-arteriosclerosis action that stimulate differentiation and proliferation of vascular endothelial cells and endothelial progenitor cells.
Patent NZ-550176-A (NZ)
Title: Intervertebral disc prosthesis or artificial vertebral body
Inventor: STUDER ARMIN
IPC: A61F2/00
Filed: 2004-04-02
Abstract: Prosthetic intervertebral disc or intervertebral implant, comprising A) a middle part 2 having a central longitudinal axis 6, an upper end 4 and a lower end 5, B) an upper apposition plate 7, which is arranged across the longitudinal axis 6 on the upper end 4 of the middle part 2 and is suitable for coming in contact with the lower plate of a vertebra, C) a lower apposition plate 8 which is arranged across the longitudinal axis 6 on the lower end of the middle part 2 and is suitable for coming in contact with the upper plate of a vertebra, and whereby D) the middle part 2 comprises elastic means 19, wherein E) the elastic means 19 have a progressive spring characteristic, F) a centering is provided for the elastic means 19, and wherein G) the middle part 2 comprises a spring 12 arranged coaxially, acting as both a tension spring and a compression spring.
Patent NZ-553544-A (NZ)
Title: A rotor blade cover for daytime visual identification of a wind power installation
Inventor: WOBBEN ALOYS
IPC: F03D11/00
Filed: 2005-08-25
Abstract: A rotor blade cover for the temporary visual identification of a wind power installation is disclosed. The rotor blade cover includes a sheath (20) of at least one colour that has releasable fixing means (24, 25) for fixing the sheath to the rotor blade (10). In use, the sheath at least partially encloses the rotor blade (10).
Patent NZ-553619-A (NZ)
Title: Curable material mixing and delivery device
Inventor: PLISHKA MICHAEL
IPC: B67D7/60
Filed: 2007-03-06
Abstract: An apparatus and method are disclosed for mixing two components and delivering the mixture to a patient. The apparatus contains a mixing chamber for mixing a liquid component and a powder component. The liquid component and powder component are mixed within the mixing chamber by rotation of a collapsible mixing element (160). A plunger (210) is then advanced through the mixing chamber to force the mixture out of the mixing chamber and deliver the mixture to the patient.
Patent NZ-554471-A (NZ)
Title: System and method for automatic response piece information retrieval
Inventor: MILLS E
IPC: G06F9/26
Filed: 2005-10-06
Abstract: A computer implemented method for retrieving information from a response piece is disclosed. The method includes: electronically analysing the response piece during delivery item processing; identifying the response piece during delivery item processing; generating an image from the analysed response piece; processing the image; and providing the image to a user.
Patent NZ-560633-A (NZ)
Title: Flavonoid compounds and uses thereof
Inventor: DUSTING GREGORY JAMES
IPC: C07F9/12
Filed: 2006-03-10
Abstract: Disclosed is a substituted flavone derivative of formula (I) wherein the substituents are as disclosed in the description. Exemplary compounds are: 4'-(Benzyloxy)-3-(benzyloxycarbonylbutylcarbonyloxy)flavone; 4'-Hydroxyflavone 3-hemiadipate; and 3',4'-Dibenzyloxy-3-(benzyloxycarbonylbutylcarbonyloxy)flavone. Also disclosed is a pharmaceutical or vetinariary composition comprising a compound of formula (I). Further disclosed is the use of a compound of formula (I) for the preparation of a medicament for treating ischemia, reperfusion injury, atherosclerosis or damage caused by the administration of a therapeutic agent.
Patent NZ-560916-A (NZ)
Title: Biphenyl-N-(4-pyridyl) methylsufonamides
Inventor: GRAMMENOS WASSILIOS
IPC: A01N43/40
Filed: 2006-03-15
Abstract: Disclosed are biphenylsulfonamides of formula I wherein the substituents are disclosed within the specification. Also disclosed are processes for preparing the compounds of formula I. Also disclosed is the use of the compound of formula I for the treatment of phytopathogenic harmful fungi and for combating harmful anthropodes.
Patent NZ-568210-A (NZ)
Title: Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines
Inventor: O'HAGAN DEREK
IPC: A61K39/39
Filed: 2006-11-06
Abstract: Disclosed is an immunogenic composition comprising a split influenza virus antigen and an oil-in-water emulsion, wherein the emulsion comprises a squalene and a free surfactant comprising polyoxyethylene sorbitan ester in its aqueous phase and wherein said composition is monovalent. Also disclosed is the use of the composition in the manufacture of a medicament for raising an immune response against an influenza virus in a subject.
Patent NZ-568722-A (NZ)
Title: System and method for rapid input of data
Inventor: EVELEIGH SIMON F
IPC: G16H10/60
Filed: 2006-11-14
Abstract: A data input system comprises a display configured to display characters and a focus indicator, an input device and a processor. The focus indicator is positioned on the display to indicate at least one changeable character from among the displayed characters. The processor is in operable communication with the display and is programmed to control the display to display the characters and to position the focus indicator based on a predetermined criterion. The input device is configured to signal the processor to display a changed value for the at least one changeable character on the display. The processor changes the position of the focus indicator if the processor determines that the position of the focus indicator must change based on the changed valued for the at least one changeable character.
Patent NZ-578844-A (NZ)
Title: Human cytomegalovirus neutralising antibodies and use thereof
Inventor: LANZAVECCHIA ANTONIO
IPC: A61P31/22
Filed: 2008-01-03
Abstract: Provided is an antibody or an antigen binding fragment thereof with specified light and heavy chain sequences, which binds human cytomegalovirus (hCMV) and, inhibits infection of endothelial cells, epithelial cells, retinal cells, or dendritic cells by hCMV. Further provided are corresponding DNA sequences coding for the antibody and cells expressing the antibody. The antibodies can be used to treat hCMV infections.
Patent NZ-579880-A (NZ)
Title: (S)-2-{ [(2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino} -propionic acid isopropyl ester
Inventor: SOFIA MICHAEL J
IPC: A61P31/14
Filed: 2008-03-26
Abstract: Disclosed is (S)-2-{ [(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino} -propionic acid isopropyl ester or a stereoisomer thereof such as (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate. Further disclosed is a composition which comprises a compound as defined above and a pharmaceutically acceptable medium for the treatment of a condition that results from an infection by hepatitis C virus, West Nile virus, yellow fever virus, dengue virus, rhinovirus, polio virus, hepatitis A virus, bovine viral diarrhea virus or Japanese encephalitis virus.
Patent NZ-580701-A (NZ)
Title: Dpp-iv inhibitor including beta-amino group, preparation method thereof and pharmaceutical composition containing the same for preventing and treating a diabetes or an obesity
Inventor: KIM HEUNG JAE
IPC: A61P3/10
Filed: 2008-04-18
Abstract: Disclosed is a compound of formula (I), wherein the substituents are as defined in the specification, and processes for their preparation.  The compounds have inhibitory activity on dipeptidyl peptidase-IV (DPP-IV).
Patent NZ-580802-A (NZ)
Title: Aryloxy-and heteroaryloxy-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
Inventor: LIU SHUANG
IPC: A61K31/55
Filed: 2008-05-08
Abstract: Disclosed are 5-aryl-2,3,4,5-tetrahydro-lH-benzo[c]azepine derivatives as represented by the general formula I(A-E), wherein: X represents a phenyl, pyridyl, naphthyl or quinolinyl group optionally substituted with one or two R14 substituents; R1 is hydrogen or alkyl; R2, R3, R5, R6, R7, R8, R9, R10 and R11 are each H; R4 is H, halogen, alkyl, piperazinyl, phenyl, pyridyl, 2-oxo-pyridin-1-yl, pyrimidinyl, pyridazinyl, 6-oxopyridazin-1-yl, pyrazinyl, pyrazolyl, [1,2,4]triazolo[4,3-a]pyridinyl, [1,2,4]triazolo[1,5-a]pyridinyl, or 3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2-yl, optionally substituted R14; R12 is alkyl, optionally substituted with 1 to 3 R15 substituents; R13 is selected from the group consisting of NR10R11 and alkyl; R14 is independently selected at each occurrence from a substituent in the group consisting of halogen, OR12, NR10R11, S(O)2R13, CN, C(O)R13 and alkyl each optionally substituted with 1 to 3 halogen atoms; or a pharmaceutically acceptable salt thereof. Representative compounds include 8-bromo-2-methyl-5-phenoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepine, 2-methyl-5-phenoxy-8-(pyridazin-3-yl)-2,3,4,5-tetrahydro-lH-benzo[c]azepine, 5-(2-fluorophenoxy)-2-methyl-8-(pyrimidin-5-yl)-2,3,4,5-tetrahydro-1H-benzo[c]azepine, 2-methyl-5-(4-(trifluoromethyl)phenoxy)-2,3,4,5-tetrahydro-1H-benzo[c]azepine and 8-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(4-fluorophenoxy)-2-methyl-2,3,4,5-tetrahydro-1H-benzo[c]azepine. Further disclosed is a pharmaceutical composition which comprises a pharmaceutically acceptable carrier and a therapeutically effective amount of the compound as defined above, for treating a disorder selected from pain, attention deficit hyperactivity disorder (ADHD), cognition impairment, anxiety disorders, panic disorder, bipolar disorder, manic depression, obsessive compulsive disorder (OCD), posttraumatic stress disorder (PTSD), acute stress disorder, social phobia, simple phobias, pre-menstrual dysphoric disorder (PMDD), social anxiety disorder (SAD), major depressive disorder (MDD), postnatal depression, dysthymia, depression associated with Alzheimer's disease, Parkinson's disease, obesity, anorexia nervosa, bulimia nervosa, binge eating disorder, analgesia, substance abuse disorders, chemical dependencies, drug addiction, neurodegenerative diseases, Parkinson's disease, sleep related eating disorder, stress urinary incontinence (SUI), migraine, diabetic neuropathy, fibromyalgia syndrome (FS), chronic fatigue syndrome (CFS), sexual dysfunction, premature ejaculation, male impotence, and thermoregulatory disorders.
Patent NZ-585871-A (NZ)
Title: Milk collecting pieces with closable chambers
Inventor: AUBURGER MARKUS
IPC: A01J5/04
Filed: 2008-12-18
Abstract: A milk collecting piece shown in sectional plan view has a housing upper part with at least two intake nozzles and a housing lower part with at least two chambers (8, 9, 18, 19) which are each flow-connected to an outtake nozzle (25) via an outlet (10, 11, 16, 17).
Patent NZ-588796-A (NZ)
Title: Crystalline form of tenofovir disoproxil and a process for its preparation
Inventor: PHULL MANJINDER SINGH
IPC: C07F9/6561
Filed: 2008-07-30
Abstract: Disclosed herein is a crystalline Form C of tenofovir disoproxil having an XRPD pattern comprising peaks at 6.8, 23.2, 25.5 and 31.7 2-theta ± 0.2 deg., and having a melting point ranging from 61 Deg. C to 66 Deg. C,.which is prepared by a process comprising adding a solution comprising tenofovir disoproxil and an organic solvent to salt-saturated water, cooling the solution to a temperature below 0 Deg. C, whereby the crystalline Form C of tenofovir disoproxil precipitates, and optionally converting the crystalline Form C of tenofovir disoproxil to an alkali or alkaline earth metal salt of crystalline Form C of tenofovir disoproxil.
Patent NZ-589547-A (NZ)
Title: Dried rasagiline base having a water content less than 0.5 % by weight
Inventor: FRENKEL ANTON
IPC: A61K31/135
Filed: 2009-06-19
Abstract: 589547 Disclosed is solid rasagiline (also known as R(+)-N-propargyl-1-aminoindan / (R)-N-(prop-2-ynyl)-2,3-dihydro-1H-inden-1-amine) containing water at an amount of less than 0.5% by weight; wherein said rasagiline may be obtainable by exposing solid rasagiline to a temperature of between 23 DEGREE C and 35 DEGREE C and a pressure of between 4-47 mbar for an amount of time suitable to dry the solid rasagiline. Further disclosed is a pharmaceutical composition comprising crystalline rasagiline as defined above and a pharmaceutically acceptable carrier, wherein said crystalline rasagiline has an X-ray diffraction pattern having peaks at 8.5, 12.6, 16.1 and 16.9.
Patent NZ-592861-A (NZ)
Title: Pharmaceutical aerosol composition
Inventor: LULLA AMAR
IPC: A61K31/137
Filed: 2009-11-04
Abstract: 592861 PHARMACEUTICAL AEROSOL COMPOSITION. A pharmaceutical aerosol composition comprising at least one hydrofluoroalkane propellant; at least one active agent complexed with an adjuvant by the method: (a) mixing the active agent in an organic solvent; (b) heating the mixture from step (a) to a suitable temperature and adding water to form a clear solution; (c) adding the adjuvant to the solution from step (b); (d) concentrating the solution from step (c) under reduced pressure to form a residue; (e) washing the residue from step (d) with the same solvent used in step (a); and (f) drying the washed residue from step (e) to form a drug-adjuvant complex. and, optionally, at least one pharmaceutically acceptable excipient. Further disclosed is methods of using the aerosol formulation to administer for the treatment of mild, moderate or severe acute or chronic symptoms of a respiratory disorder with a medication selected from antiallergics, anticholinergics or bronchodilators such as tiotropium, salbutamol, beclomethasone, ipratropium, formoterol, aclidinium, salmeterol, fluticasone, budesonide, fenoterol, ciclesonide or mometasone
Patent NZ-597029-A (NZ)
Title: Microcapsules containing agrochemicals, processes for preparing them and their use
Inventor: MULQUEEN PATRIC JOSEPH
IPC: A01N25/04
Filed: 2006-12-22
Abstract: Disclosed herein microcapsules which comprise a biologically active compound and processes for the preparation and for the use of such microcapsules. Particularly disclosed is a product comprising microcapsules which themselves comprise (a) a polymeric shell; and (b) a core which comprises an agrochemical which has a melting point above 25C characterised in that the agrochemical is dispersed as a solid in a hydrophobic material which has a melting point greater than or equal to 25C but which does not exhibit a glass transition temperature, and where the agrochemical has a water-solubility in the range of 0.1 to 100 g/l at 20°C, and is selected from the group consisting of insecticides, herbicides, fungicides, acaricides, rodenticides, molluscicides and plant growth regulators. A process for preparing said product is also disclosed, comprising the steps (i) melting the hydrophobic material to form a hydrophobic liquid; (ii) dispersing the agrochemical in the hydrophobic liquid; (iii) emulsifying the hydrophobic liquid into an aqueous phase; (iv) optionally cooling the resultant emulsion; (v) causing an interfacial polymerisation reaction to occur at the interface between the hydrophobic liquid and the aqueous phase to produce a capsule suspension; and (vi) optionally allowing or causing the capsule suspension to cool.
Patent NZ-606493-A (NZ)
Title: Particulate substances comprising ceramic particles for delivery of biomolecules
Inventor: BARBÉ CHRISTOPHE JEAN ALEXANDRE
IPC: C01B33/18
Filed: 2011-08-15
Abstract: Disclosed is a particulate substance comprising: - particles of a ceramic matrix bearing a functional group, the functional group being capable of promoting penetration of the particles into cells and being distributed homogeneously throughout said particles; and - a biomolecule having hydrophilic properties disposed within pores of the particles, the biomolecule being releasable from the particles by dissolution of the ceramic matrix.
Patent NZ-609394-A (NZ)
Title: Quantification and characterization of allergens
Inventor: YOUNG SCOTT A
IPC: G01N33/00
Filed: 2011-08-22
Abstract: Discloses a method of determining an amount of lipid transfer protein (LTP) allergen in maize kernel, the method comprising: Partially purified maize-derived LTP allergen having a molecular mass of 9 kDa from ground maize kernel to form an extract; and determining the amount of the maize-derived LTP allergen in the extract using liquid chromatography with ultraviolet and mass spectrometric detection.
Patent NZ-617505-A (NZ)
Title: Thiazole compound and preparation method and use thereof
Inventor: DING JIAN
IPC: C07D417/04
Filed: 2012-05-07
Abstract: Disclosed herein is a class of thiazole compounds of general formula (I), wherein R1 is a thiazolyl or thiophenyl group and the other variables are defined in the specification, and the preparation method and use thereof. More particularly, disclosed is a derivative of natural product largazole, the preparation method thereof and the use in the field of antitumor and multiple sclerosis treatment as a histone deacetylase inhibitor.
Patent NZ-617655-A (NZ)
Title: Load cell for screw piling power head
Inventor: WAYNE MCILRAVEY
IPC: G01L5/10
Filed: 2013-11-12
Abstract: Disclosed is a load pin adapted to be combined with a machine suitable for driving a screw pile into the ground. The load pin includes an outer surface, a longitudinal axis extending between opposing ends and a medial portion having a center point along said longitudinal axis. A sensor (16) is combined with the pin and measures forces applied thereto. The sensor (16) is comprised of four gauges (R1, R3, R5, R7) which are electrically connected using a differential bridge electronic circuit. The sensor (16) is a shear type foil strain gauge sensor.
Patent NZ-619175-A (NZ)
Title: Stable crystal modifications of dotap chloride
Inventor: PLATSCHER MICHAEL WILHELM
IPC: C07C219/08
Filed: 2012-05-02
Abstract: The present disclosure relates to a process for preparing crystal modifications of racemic (2R,S)- and enantiomerically pure (2R)- resp. (2S)-DOTAP chloride (N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-1-propanaminium chloride, also known as (Z,Z)-N,N,N-trimethyl-2,3-bis[(1-oxo-9-octadecenyl)oxy]-1-propanaminium chloride or 1,2-dioleoyloxy-3-trimethylammonium propane chloride) and the hydrates thereof, and to the use of the compound for the preparation of pharmaceutical compositions. The process has a recrystallisation step involving slow cooling at a rate of 0.001°C to 0.1°C per minute.
Patent NZ-620418-A (NZ)
Title: Pharmaceutical compositions comprising rifaximin, processes for their preparation and their use in the treatment of vaginal infections
Inventor: VISCOMI GIUSEPPE CLAUDIO
IPC: A61K31/437
Filed: 2012-07-26
Abstract: Provided are pharmaceutical compositions comprising rifaximin granules useful in the treatment of vaginal infections. A preferred pharmaceutical composition comprises: (a) rifaximin granules comprising rifaximin in an amount from 2.5 mg to 200 5 mg and one or more intragranular excipients including at least one binder selected from the group consisting of corn starch, pregelatinized starch, arabic gum, lactose, maltodextrine, copolymer of 1 vinyl-2 pyrrolidone and vinylacetate (copovidone), saccharose and mixtures thereof; and (b) one or more extragranular excipients including at least one disintegrant wherein said extragranular disintegrant is selected from crospovidone, calcium silicate and mixtures thereof; in the form of a vaginal tablet, optionally coated with a film coating.
Patent NZ-625001-A (NZ)
Title: Combinations of antifungal compounds and tea tree oil
Inventor: REUVENI MOSHE
IPC: A01P3/00
Filed: 2012-11-08
Abstract: Disclosed are methods for treating a plant infection caused by a fungus of the phylum basidiomycota, comprising applying to the plant a combination of tea tree oil (TTO) and a synthetic fungicidal compound such as copper hydroxide. The composition is used to treat rust infection in coffee pants, garlic plants, green onions, and soybean.