baber/WOPTO huggingface dataset:
Patent NZ-334637-A (NZ)
Title: Hybride polypeptides, their encapsulation within a modified starch and administration of the starch to animals
Inventor: KEELING PETER
IPC: C12N15/82
Filed: 1997-09-30
Abstract: The present invention relates to a recombinant nucleic acid encoding a hybrid polypeptide which comprises a transit peptide for the translocation of the polypeptide into an appropriate organelles such as plastids, a starch-encapsulating region from maize starch synthase and a payload polypeptide, wherein said payload polypeptide can be either N- or C-terminal to the starch encapsulating region. The invention also relates to the expression vectors comprising said nucleic acid, and hosts comprising the said vector. Also, the invention encompasses methods of producing the hybrid polypeptide thereof from starch and particularly from starch granules, and industrial uses of the payload polypeptide recombinantly produced in said hybrid polypeptide wherein said payload polypeptide is a biologically active molecule.
Patent NZ-335231-A (NZ)
Title: Human fragments of insulin C-peptides of the sequence ELGGGPGAG or EGSLQ that have Na/K ATPase stimulating activity
Inventor: WAHREN JOHN
IPC: C07K14/62
Filed: 1997-09-26
Abstract: A peptide being a fragment of the human insulin C-peptide, the peptide comprising the sequence ELGGGPGAG or a fragment thereof, or the sequence EGSLQ or a fragment thereof, and having the ability to stimulate Na+K+ATPase activity. Further provided are biomimetic organic compounds exhibiting activation of Na+K+ATPase activity and/or cellular binding to renal tubule cells and fibroblasts at least at the level exhibited by the aforementioned peptides or their fragments. Such peptides and compounds have utility in combating diabetes and diabetic complications, or for stimulating Na+K+ATPase activity.
Patent NZ-335360-A (NZ)
Title: Use of products having enzymatic activity to produce food that when consumed induces antisecretory proteins
Inventor: LANGE STETAN
IPC: A23L7/20
Filed: 1997-11-14
Abstract: The use of products having enzymatic activity for the preparation of a food, including feed, inducing, when consumed, antisecretory proteins and the foods thus prepared. The products having enzymatic activity may for example be malted cereals.
Patent NZ-335867-A (NZ)
Title: Mobile ladder including a goods lift
Inventor: MOFFAT WILLIAM
IPC: E06C7/12
Filed: 1997-10-22
Abstract: A mobile ladder (10) including a goods lift (12) which can be driven between upper (FIG. 3) and lower (FIG. 4) positions. The ladder has a default-immobile state which can be overcome by a force manually applied to a handle. The ladder can then be moved and steered via the handle.
Patent NZ-336535-A (NZ)
Title: Application system for sliders at form-fill-seal machine
Inventor: MCMAHON MICHAEL J
IPC: B65B9/213
Filed: 1999-07-01
Abstract: The specification describes an FFS apparatus for making reclosable plastic bags with slider zippers.  The apparatus is best illustrated by figure 8 above wherein: (i)	a thermoplastic film(102) is fed continuously into a FFS machine (100) and wrapped around a collar (104) and filling tube (104) to bring the longititudinal edges (108,110) of the film (102) together to form a tube. (ii)	The interlocked zipper (10) which has sliders (54) preapplied to it is then fed in a continuous coil (112) between the longititudinal edges (108,110) of the film (102). (iii)	Vertical seal bars (114) seal the zipper flanges (24,42) to the longititudinal edges (108,110) to form the top of the bag. The sliders must be clear of the vertical seal bars so that the sliders do not interfere in the sealing of the zipper and are not crushed by the vertical seal bars.  It is critical that the zipper flanges are long enough to eliminate any interference between the sliders and the seal bars.
Patent NZ-500184-A (NZ)
Title: Trans-platinum compound for use in labelling biological molecules and diagnostic kit
Inventor: HOUTHOFF HENDRIK JAN
IPC: G01N33/543
Filed: 1998-04-09
Abstract: A trans-platinum based compound of formula (I) for use in a method for labeling a bio-organic molecule, wherein:  A represents a reactive moiety for attachment to a label;  D represents a reactive moiety for attachment to a bio-organic molecule; and  X1 and X2 represent the same or different inert moieties.
Patent NZ-506465-A (NZ)
Title: Derivatives of azetidine and pyrrolidine
Inventor: BROEKKAMP CHRISTOPHORUS LOUIS
IPC: C07D205/04
Filed: 1998-02-26
Abstract: A compound of formula (I) and pharmaceutically acceptable salt thereof having antidepressant activity that can be used in treating or preventing serotonin-related diseases is disclosed, wherein: A is an optionally unsaturated 5- or 6-membered ring, which may comprise a heteroatom selected from N, O and S and which may be substituted with oxo or (1-6C)alkyl; R1, R2 and R3 are independently H, (1-6C)alkyl, (1-6C)alkoxy, (1-6C)alkoxy-(1-6C)alkyl, carbo(1-6C)alkoxy or halogen; X is O or S; and n is 1 or 2; or, with the exception of 3-(naphth-1-yl-oxy)-pyrrolidin, 3-(5,6,7,8-tetrahydro-naphth-1-yl-oxy)-pyrrolidin and 3-[(1-methyl-indol-4-yl)oxy)]-pyrrolidin.
Patent NZ-508121-A (NZ)
Title: Mixtures of cyclic and linear poly L-lactates for use in the treatment of malignant neoplasms
Inventor: NAGASU YOUICHIRO
IPC: A61K31/765
Filed: 2000-11-13
Abstract: A method of preparing an anti-malignant tumor agent comprising a mixture of poly L-lactates that are cyclic and linear oligomers having degrees of condensation of 3 to 23, the method comprising dehydration condensation of L-lactic acid in a nitrogen atmosphere under stepwise reduced pressure and at an increasing temperature, drying ethanol- and methanol-soluble components in the resulting reaction solution under reduced pressured, subjecting the product to chromatography on a reverse phase ODS column, and after elution with 25 to 50% aqueous acetonitrile at pH 2.0, giving the mixture of poly L-lactates as a fraction eluted with 100% acetonitrile at pH 2.0.
Patent NZ-513729-A (NZ)
Title: System and method for processing financial transactions
Inventor: GIORDANO JOSEPH A
IPC: G07G1/00
Filed: 2000-02-18
Abstract: A network for processing retail sales transactions includes a customer transceiver with a unique customer number, a reader receiving the customer number and sending it to a point-of-sale device (34) where it is combined with transaction information to form a transaction entry. The transaction entry is sent through a merchant computer to a transaction processing system (26) having a customer database. The transaction processing system (26) references an entry in the customer database corresponding to the customer/transmitter ID number and routes the transaction entry to a payment processing system (16) specified in the customer database entry.
Patent NZ-515501-A (NZ)
Title: Use of pyrazolo[4,3-d]pyrimidin-7-ones, pyrazolo[3,4-d]pyrimidin-4-ones, quinazolin-4-ones, purin-6-ones, pyrido[3,2-d]pyrimidin-4-ones and tetracyclic derivatives to treat nitrate-induced tolerance
Inventor: ELLIS PETER
IPC: A61K31/4985
Filed: 1999-11-29
Abstract: Use of cyclic guanosine mono-phosphate (cGMP) phosphodiesterase (PDE) inhibitors from the group of: pyrazolo[4,3-d]pyrimidin-7-ones, pyrazolo[3,4-d]pyrimidin-4-ones, quinazolin-4-ones, purin-6-ones, pyrido[3,2-d]pyrimidin-4-ones and their tetracyclic derivatives in the manufacture of medicaments to treat nitrate-induced tolerance.
Patent NZ-516057-A (NZ)
Title: Mixing apparatus and method of mixing
Inventor: ANDREWES DAVID
IPC: B01L3/00
Filed: 2000-06-09
Abstract: Apparatus, instrument, device and a method of mixing are disclosed for conducting an assay. Apparatus includes a first and second inlet and an inlet port accommodating a filter and/or binder retaining means, the inlet port moveable relative to first and second inlets such that the port can be brought into liquid communication with each inlet, and a sample chamber (3, 5) comprising a paddle (100) which undergoes a reciprocating motion.
Patent NZ-523407-A (NZ)
Title: 3-Hydroxymethyl-benzo[b]thiophene derivatives and process for making the same
Inventor: SAITOU HIROSI
IPC: C07D333/56
Filed: 2002-05-02
Abstract: A method of producing a 3-hydroxymethyl-benzo[b]thiophene derivative without the possible concomitant formation of isomers is disclosed, which comprises selectively cyclizing a sulfoxide having X shown in the reaction scheme below, wherein R1 to R3 are, same or independently, a hydrogen atom, an alkyl group having 1 to 4 carbons, a trihalomethyl group, an alkoxy group having 1 to 4 carbons, an alkylthio group having 1 to 4 carbons, or a trihalomethoxy group; R4 is an acyl group; X is a halogen atom, a hydroxy group or an acyloxy group having 1 to 9 carbons.
Patent NZ-527119-A (NZ)
Title: Building method
Inventor: SMITH CRAIG WILLIAM
IPC: E04B1/26
Filed: 2003-07-21
Abstract: A building component comprising an elongate narrow base web (302) for securement to a top or bottom plate edge or face edge of a wall panel, and a plurality of elongate planar tie elements (303, 305) extending from opposed edges of the base web in a direction normal to the base web, the ties arranged in pairs with the ties of each pair located directly opposed across the elongate base, the ties being spaced at regular intervals along the elongate base. Also disclosed is a joist hanger (Figure 9); joist hanger bracket (Figure 4, item 409); method of building construction (Figure 17); a ventilation packer (Figure 2c); a corner arrangement (Figure 6).
Patent NZ-527124-A (NZ)
Title: Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
Inventor: ISFORT ROBERT JOSEPH
IPC: A61K48/00
Filed: 2002-03-06
Abstract: A method for identifying candidate compounds for regulating skeletal muscle mass or function, comprising: (a) contacting a test compound with a CRF2R receptor, (b) determining whether the test compound binds to the CRF2R receptor, (c) selecting those compounds that bind CRF2R receptor and further determining whether the test compound increases muscle mass or function in a skeletal muscle atrophy model system, and (d) identifying those test compounds that modulate muscle mass or function as candidate compounds for regulating skeletal muscle mass or function. Compounds identified by the above method are used in the manufacture of medicaments for increasing skeletal muscle mass or function in a subject.
Patent NZ-528505-A (NZ)
Title: Automated cleansing sprayer
Inventor: LINSTEDT BRIAN K
IPC: B05B3/10
Filed: 2002-04-12
Abstract: The invention is an automated sprayer for spraying the walls of a bath and shower enclosure with a cleanser. The sprayer has a housing that can be mounted inside the shower enclosure and that defines a tray in which an inverted bottle of cleanser is stored. The bottom of the tray has a tube extending downwardly along a longitudinal axis through which the cleanser can pass. A motorized head disposed beneath the tube can be rotated about the axis for metering cleanser from the bottle and spraying cleanser outward. The sprayer includes timer circuitry that delays commencement of a spray for a set time and automatically stops spraying after a predetermined period. The sprayer also includes a system for signaling the beginning of a spray cycle including audio and visual alarms. An automated method of cleaning the shower enclosure is also disclosed.
Patent NZ-531445-A (NZ)
Title: Three-step conversion of protected taxane ester to paclitaxel
Inventor: ZYGMUNT JAN
IPC: C07D305/14
Filed: 2002-04-25
Abstract: A method of producing paclitaxel from a protected coupled ester compound of formula (I) is disclosed, wherein P1 is a hydrogenatable protecting group, comprising the steps of (a) deprotecting the 7-O-position and 3'-N-position of the protected coupled ester compound to form a first intermediate compound of formula (II); (b) benzoylating the first intermediate compound at the 3'-N-position thereby to form a second intermediate compound of formula (III); and (c) deprotecting the second intermediate compound by replacing P1 with hydrogen in the presence of an acid. Also disclosed are chemical compounds that are useful in the production of paclitaxel.
Patent NZ-540155-A (NZ)
Title: Peptides that modulate gap junction intercellular communication (GJIC).for use in the treatment or prevention of pathologies associated with impaired GJIC
Inventor: LARSEN BJARNE DUE
IPC: A61P9/06
Filed: 2003-11-25
Abstract: Disclosed are dipeptides that facilitate the intercellular communication mediated by gap junctions. Applications comprise use in the treatment of diseases associated with impaired gap junction intracellular communication (GJIC). A peptide is represented by the general formula 1: wherein, if a is 1 then b is 0; wherein z is 1-7; p, q, x and y are selected from 0 or 1; wherein if x is 1 then y and q are 1 and p is 0; wherein if p is 1 then x and q are 0 and y is 1; and further, wherein if R1 is H then d is 0-8; wherein if R1 is not H then d is 0; wherein R1 is the side chain of an amino acid selected from the group consisting of alanine, arginine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, and valine ; wherein R2 is selected from the group consisting of NH2, NHR, NR2, NR3+H, OH, SH, RO, RS, RSO, RSO2, COR, CSR, COOH, COOR, CONH2, CONHR, CONR2, OCOR, and SCOR;, wherein R = alkyl, alkenyl, aryl, aralkyl, or cycloalkyl; wherein R3 = H or CH3; and wherein Rx is a hydrophobic group.
Patent NZ-543512-A (NZ)
Title: Interaction of PD-L2 with PD-1 transmits a negative signal to immune cells, downregulating immune responses
Inventor: FREEMAN GORDON
IPC: A61K48/00
Filed: 2001-06-28
Abstract: Provided is a use, in the manufacture of a medicament, of a combination of: i) a non-activating antibody that recognizes PD-L2, and ii) a non-activating antibody that recognizes PD-L1, thereby modulating the activity ofPD-L2 and/or modulating the interaction ofPD-L2 and its natural binding partner(s), for upregulating an immune response in a patient in need thereof, wherein PD-L2 is encoded by a nucleic acid molecule selected from a group consisting of: a) a nucleic acid molecule comprising a nucleotide sequence which is at least 70% identical to a specified nucleotide sequence, b) a nucleic acid molecule comprising a fragment of at least 50 nucleotides of a nucleic acid comprising the said nucleotide sequence, which includes at least 15 contiguous nucleotides, c) a nucleic acid molecule which encodes a polypeptide comprising an amino acid sequence at least about 71% identical to a specified amino acid sequence; d) a nucleic acid molecule which encodes a fragment of a polypeptide comprising the said amino acid sequence, wherein the fragment comprises at least 20 contiguous amino acid residues of the said amino acid sequence; and wherein the medicament is formulated for separate, sequential or simultaneous administration of i) and ii); and when the immune response is selected from the group consisting of severe combined immunodeficiency, multiple sclerosis, systemic lupus erythematosus, type I diabetes mellitus, lympho proliferative syndrome, inflammatory bowel disease, allergies, asthma, graft-versus-host disease, transplant rejection, immune response to infectious pathogens, immune system cancer, lymphoma and leukaemia. Further provided are related methods of identifying test compounds modulating binding of PD-L2 to PD-1.
Patent NZ-543968-A (NZ)
Title: Photo-activated disinfection
Inventor: COLLES MICHAEL JOHN
IPC: A61C1/08
Filed: 2004-05-21
Abstract: Disclosed is an apparatus that relates to photo-activated disinfection in an oral cavity (25). We describe a dental apparatus comprising a light source (20) producing light at a predetermined wavelength and power, and optical transmission means (21) to train the light from the light source onto at least one external side of a tooth (23). Preferably, the optical transmission means comprises at least one optical guide (21). In a preferred embodiment, the optical transmission means comprises a pair of substantially parallel elongate light guides, each light guide having a distal end provided with a reflective surface (22) inclined at 45° to the direction of light transmission along the light guides, the reflective surfaces of the light guides being opposed such that light rays (24) emitted from each light guide are parallel but opposite in direction. Preferably, the light source is a light emitting diode or array of light emitting diodes and the light has a wavelength of from 550 to 690 nm, more preferably from 600nm to 680nm, even more preferably from 625 to 660nm.
Patent NZ-545120-A (NZ)
Title: Fish protein hydrolyzate capable of lowering the concentration of cholesterol in plasma and triglycerides in the liver
Inventor: BERGE ROLF
IPC: A61P3/06
Filed: 2004-07-02
Abstract: Disclosed is the use of an enzyme treated fish protein hydrolysate material for the preparation of a pharmaceutical or nutritional preparation for the treatment and/or prevention of fatty liver, hypercholesterolemia or hyperhomocysteinemia in an animal and processes for its preparation.
Patent NZ-545364-A (NZ)
Title: HPV CD8+ T-cell epitopes
Inventor: HARDING FIONA A
IPC: C12Q1/68
Filed: 2004-08-23
Abstract: Provided is a method for determining a CD8+ T-cell epitope in a protein, comprising the steps of: (a) differentiating a solution of dendritic cells and a solution of naïve CD8+ T-cells from a single human blood source obtained from a human to produce a solution of differentiated dendritic cells; (b) preparing a pepset of peptides from said protein, wherein said pepset comprises said T-cell epitope; (c) combining said solution of said CD8+ T-cells and an anti -CD40 antibody to provide a T-cell and antibody solution, (d) combining said differentiated dendritic cells with each peptide separately in said pepset with said T-cell and antibody solution; and (e) measuring the proliferation of said T-cells in said step (d), to identify said peptide as a CD8+ T-cell epitope wherein said protein is not a human papillomavirus (HPV) protein. Further provided are methods of reducing allergenicity or increasing immunogenicity of a protein comprising modifying such identified epitopes.
Patent NZ-553879-A (NZ)
Title: Enhanced plant growth
Inventor: FLOREY LYNDA KAY
IPC: A01N65/00
Filed: 2007-03-15
Abstract: Disclosed is a method of enhancing growth of root crops, tuber crops, and/or vine crops (excluding tomatoes) comprising adding to a body of soil a humate or humate containing substance pre-mixed with a mineral or mineral containing substance where the pre-mix comprises an effective amount of a suitable sugar or sugar containing substance. Also disclosed is a plant growth enhancer for use with root crops, tuber crops, and/or vine crops (excluding tomatoes) comprising a humate or humate containing substance mixed with a mineral or mineral containing substance so that the mixture is able to deliver a synergistic benefit to crop soil in terms of enhancing plant growth wherein the mixture comprises an effective amount of a suitable sugar or sugar containing substance.
Patent NZ-554724-A (NZ)
Title: Biphenyl-3-yl acetic acids and derivatives thereof
Inventor: WILSON FRANCIS
IPC: C07C59/72
Filed: 2005-10-21
Abstract: The disclosure relates to biphenyl-3-yl carboxylic acids derivatives of formula (I) with the definitions of A, X, R1-R6 given in the specification, and/or a salt or ester thereof. Furthermore the disclosure relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of gamma-secretase activity.
Patent NZ-554909-A (NZ)
Title: Identification device and method for manufacturing thereof
Inventor: VAN WIJK ANTOON
IPC: A01K11/00
Filed: 2005-10-20
Abstract: An animal tag, possibly fitted with an electronic transponder, includes a male part with an arrow shaped element and a female part provided with a passage having a front end 3 and a rear end 4. The arrow shaped element can be inserted into the passage along the front end. The passage is provided close to the front end with at least one protruding element 8 and is partly closed close to the rear end by a closing part 9. The passage, including the protruding element, is manufactured integrally from a hard plastic material.
Patent NZ-556080-A (NZ)
Title: Substituted 4-phenyltetrahydroisoquinolines, methods for producing them, their use as drug, and drug containing them
Inventor: HEINELT UWE
IPC: C07D217/14
Filed: 2005-12-30
Abstract: Disclosed is a compound of formula I, wherein the substituents are as defined in the specification. The compounds are NHE inhibitors useful in the treatment of various diseases, and can be used, inter alia, for renal disease, for biliary dysfunction and for respiratory disorders such as snoring or sleep apnoea.
Patent NZ-566080-A (NZ)
Title: Needle assembly for a prefilled syringe system
Inventor: FABIAN ARTHUR
IPC: A61M5/32
Filed: 2006-08-03
Abstract: A needle assembly (10) for a prefilled injection syringe is described. A needle holder (12) has a needle (14) secured to it and is adapted to be secured to a syringe barrel of the injection syringe. A needle sheath (16) has a distal end forming a releasable sterile seal with the needle holder (12), and surrounds and shields the needle (14) . A needle seal (18) surmounts the needle tip and is arranged at least in part in the proximal end of the needle sheath (16) and closed off by a closure element (20). A closure connection between the closure element (20) and the needle sheath (16) is configured as a non-releasable and sterile barrier (54) produced by means of bonding or welding.
Patent NZ-566904-A (NZ)
Title: A dehumidifier which can select air outlets using a damper mechanism
Inventor: SHIBATA HIDEO
IPC: D06F58/00
Filed: 2007-01-12
Abstract: A dehumidifier which can discharge not only cold air, and cold air and mixed air, but also warm air from an air outlet in order to speed up drying of laundry and to finish the laundry well and to enhance dew condensation prevention function is disclosed. The dehumidification machine has at least an evaporator (15) and a condenser (16). It includes a first air blower and second air blower (20) and a damper mechanism. The first air blower introduces cool air from the evaporator into a first air path. The second air blower (20) introduces warm air from the condenser into a second air path. The damper mechanism is capable of selecting whether the cool air flow is blown out from a front-face side blowing outlet (8) or a back-face blowing outlet (11). It also selects whether the warm air flow is blown out from the front-face side blowing outlet or the back-face blowing outlet. At the time of shutdown of a refrigerating cycle the damper mechanism also selects that both air flows are blown out from the back-face blowing outlet (11).
Patent NZ-578204-A (NZ)
Title: Compositions comprising bile acid sequestrants for treating esophageal disorders
Inventor: CURRIE MARK G
IPC: A61K33/10
Filed: 2007-12-21
Abstract: Disclosed is a sustained-release pharmaceutical dosage form adapted for oral administration to a subject in need thereof, comprising a therapeutically effective amount of at least one bile acid sequestrant selected from colesevelam and colesevelam hydrochloride and a gastric-retention vehicle composition comprising one or more hydrogels, wherein said dosage form is adapted for use in preventing or treating an esophageal disorder selected from heartburn, erosive esophagitis, GERD, esophagitis, Barrett's esophagus, esophageal adenocarcinona and non-responsive GERD. Also disclosed is the use of the dosage form in the manufacture of a medicament for preventing or treating an esophageal disorder selected from heartburn, erosive esophagitis, GERD, esophagitis, Barrett's esophagus, esophageal adenocarcinona and non-responsive GERD.