baber/WOPTO huggingface dataset:
Patent IL-104124-A0 (IL)
Title: Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring
IPC: A61K31/4427
Filed: 1992-12-17
Abstract: Disclosed is a compound of formula (1.0) or a pharmaceutically acceptable salt or solvate thereof. Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier and an effective amount of a compound of formula (1.0). Further disclosed is a method of treating allergy (for example asthma), inflammation, hypertension, raised intraocular pressure (such as glaucoma), i.e., a method of lowering intraocular pressure, sleeping disorders, states of hyper and hypo motility and acidic secretion of the gastrointestinal tract, hypo and hyperactivity of the central nervous system (for example, agitation and depression) and other CNS disorders (such as Alzheimers, Schizophrenia, and migraine) comprising administering an effective amount of a compound of formula (1.0) to a patient in need of such treatment.
Patent IL-105758-A0 (IL)
Title: Indexable-insert drill
IPC: B23B51/00
Filed: 1993-05-20
Abstract: PCT No. PCT/EP94/01626 Sec. 371 Date Mar. 16, 1995 Sec. 102(e) Date Mar. 16, 1995 PCT Filed May 19, 1994 PCT Pub. No. WO94/27772 PCT Pub. Date Dec. 8, 1994A drilling tool having an elongated body with a longitudinal axis and provided with at least one insert receiving pocket and an indexable cutting insert for use with the drilling tool for performing drilling action is disclosed. The insert of the drilling tool includes a rake face, relief flank faces, a base, a plurality of cutting edges, each defined between the rake face and adjacent relief flank face and included between two adjacent cutting corners. Each cutting edge has at least one set of component cutting edges, each set having two pairs of component cutting edges merging in a common point, each pair comprising a first and a second component cutting edge merging via a bridging section directed towards a central line constituting or parallel to a median line of the insert and passing through the common point. The component cutting edges are oriented with respect to the central line so that an outermost extremity of the second component cutting edge is closer to a center of the insert and to the central line than the outermost extremity of the first component cutting edge. This ensures that during the drilling action, a line parallel to the longitudinal axis and passing through the outermost extremity of the first component cutting edge intersects the second component cutting edge and the extremities overlap.
Patent IL-107434-A0 (IL)
Title: Calcium channel blocking polypeptides from theraphosidae aphnopelma
IPC: A61P15/00
Filed: 1993-10-28
Abstract: Polypeptides isolated from the venom of the Theraphosidae aphonopelma spider block calcium channels in cells of various organisms and are useful in blocking said calcium channels in cells, per se, in the treatment of calcium channel-mediated diseases and conditions and in the control of invertebrate pests.
Patent IL-112656-A0 (IL)
Title: A thermal desorption process and apparatus
IPC: C07C51/47
Filed: 1995-02-15
Abstract: Described are preferred processes and apparatuses for thermally desorbing desired chemical products from resins to which they are adsorbed. The processes and apparatuses provide highly efficient use of applied heat throughout resin preheat, desorption and cooling phases.
Patent IL-117923-A0 (IL)
Title: Pyrido [2,3-d] pyrimidine derivatives and pharmaceutical compositions containing them
IPC: A61P35/00
Filed: 1996-04-16
Abstract: 6-Aryl pyrido[2,3-d]pyrimidine 7-imines, 7-ones, and 7-thiones o f formula (I) are inhibitors of protein tyrosine kinases, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating cancer, atherosclerosis, restenosis, and psoriasis.
Patent IL-133665-A0 (IL)
Title: Connector system
IPC: F16L37/00
Filed: 1998-07-03
Abstract: The connector system comprises an upstream tubular body (1) capable of being connected to a pressurized-fluid line and in which there is placed a first shutter (18) bearing against a seat (6) under the action of a spring (20) upstream of the shutter. A downstream tubular body (2), that can be plugged into the upstream tubular body (1) and is capable of being connected to a line receiving the pressurized fluid, contains a second shutter (49) bearing against a seat (38) under the action of a spring (51) downstream of this shutter and of spring force equal to or less that that of the spring (20). A push-rod (24) and a tubular wall (25) which are fixed to the first shutter (18) downstream thereof interact with a push-rod (55) fixed to the second shutter (49) upstream thereof and with an upstream edge (57) of the downstream tubular body (2). The upstream tubular body (1) is mounted in a socket (29) provided with a counterbore (31) and with a catching groove (32). The downstream tubular body (2) is housed in a plug (60) capable of being introduced into the counterbore (31) and provided with elastic tabs (63) with teeth (64) for clipping into the catching groove (32). An operating ring (67) that can move along the plug (60) comprises openings (69) forming ramps for withdrawing the clip-in teeth (64) from the catching groove (32).
Patent IL-134382-A0 (IL)
Title: Thyromimetic antiobesity agents
IPC: A61K31/195
Filed: 2000-02-03
Abstract: The invention relates to pharmaceutical compositions and methods useful in the treatment of obesity which methods comprise administering to animal, including a human or companion animal, in need of such treatment an effective amount of a compound of the structural formula <CHEM> or a pharmaceutically acceptable salt, racemate or enantiomer thereof, wherein     R is hydroxy, esterified hydroxy or etherified hydroxy; R1 and R2 are, independently, halogen, trifluoromethyl or lower alkyl; R3 is halogen, trifluoromethyl, lower alkyl, aryl, aryl-lower alkyl, cycloalkyl or cycloalkyl-lower alkyl, carbocyclic arylmethyl, carbocyclic aroyl, carbocyclic arylhydroxymethyl; or   R3 is the radical <CHEM>  wherein R8 is hydrogen, lower alkyl, aryl, cycloalkyl, aryl-lower alkyl or cycloalkyl-lower alkyl; R9 is hydroxy or acyloxy; R10 is hydrogen or lower alkyl; or R9 and R10, taken together with the carbon atom to which they are attached, form a carbonyl group;   R4 is hydrogen, halogen, trifluoromethyl or lower alkyl; R5 and R6 are, independently, hydrogen or lower alkyl or R5 and R6, taken together with the carbon atom to which they are attached, form a carbonyl group;   X is O, S or -NR7;   R7 is hydrogen or lower alkyl;   W is O or S; and Z is carboxyl or carboxyl derivatized as a pharmaceutically acceptable ester or amide.   The invention further provides for pharmaceutical compositions and methods of using the compounds of structural formula (I), or the pharmaceutically acceptable salts, racemates and enantiomers thereof, in combination with an anorectic agent, in treating obesity.
Patent IL-137500-A0 (IL)
Title: Pencil sharpener
IPC: B43L23/08
Filed: 2000-03-10
Abstract: There is described herein a sharpener for a carpenter's pencil having a centering collar mounted to an enclosure for relative rotation to generate the sharpening effect. Within the base enclosure there is a symmetrical pencil point contour surface and a blade mounted along the contour for cutting against the inserted pencil. The shape of the blade is either curved or formed from a plurality of sections to produce a narrow cut around the point extremity of the pencil and a wider cut further up the pencil shaft.
Patent IL-140072-A0 (IL)
Title: Formulations for controlling lice in humans
IPC: C11D3/20
Filed: 1999-06-21
Abstract: Safer pediculicidal formulations comprising a spinosyn, or a physiologically acceptable derivative or salt thereof, and a physiologically acceptable carrier, and methods of controlling lice infestations in a human with these formulations are provided.
Patent IL-145344-A0 (IL)
Title: Food complement and method for cosmetic treatment based on a grape extract rich in polyphenols
IPC: A61K31/352
Filed: 2000-03-13
Abstract: The invention concerns firstly a food complement for dietetic and/or cosmetic purposes, containing anti-lipase properties, for oral administration. Said food complement is characterised in that it comprises a grape extract rich in or enriched with polyphenols.
Patent IL-145565-A0 (IL)
Title: Pyridine-2,3-dicarboxylic acid diamides
IPC: C07D213/89
Filed: 2000-03-31
Abstract: The present invention relates to substituted aniline compounds of the formula 1in which R<21>, R<22 >and R<23 >have the meanings indicated in the description. The compounds according to the invention are intermediates for the preparation of herbicidally active pyridinedicarboxamide compounds.
Patent IL-154593-A0 (IL)
Title: 3-(heteroaryl acetamido)-2-oxoazetidine-1-sulfonic acid derivatives as antibacterial agents
IPC: A61P31/04
Filed: 2001-09-14
Abstract: The present invention relates to novel Syn isomers of racemates and optical isomers of 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids of the following formula: and their use in treating infections caused by gram-negative pathogenic bacteria.
Patent IL-155210-A0 (IL)
Title: Preparation of anthropodicidal oxadiazines
IPC: C07C69/757
Filed: 2003-04-02
Abstract: A method for making a compound of Formula I which is racemic or enantiomerically enriched at chiral center* comprising hydrogenating a compound of Formula V in the presence of a compound of Formula VII    
wherein:  R 1  is F, Cl, or C 1 -C 3  fluoroalkoxy,  R 2  is C 1 -C 3  alkyl, and  R 3  is CO 2 CH 2 (C 6 H 5 ).
Patent IL-161319-A0 (IL)
Title: Use of thymulin-like peptides for making pain-relieving medicines
Inventor: SAADE NAYEF
IPC: C07K7/06
Filed: 2002-10-08
Abstract: The present invention relates to the utilization of peptide analogues of thymulin that are inactive relative to the immune system, not comprising zinc and having anti-pain activity, for manufacturing a medicine for the treatment of pain.
Patent IL-162506-A0 (IL)
Title: Ovulation induction
IPC: A61P15/08
Filed: 2001-12-14
Abstract: The present invention relates to inducing ovulation in a female host comprising the administration of a non-polypeptide cyclic adenosine monophosphate (cAMP) level modulator selected from Roflumilast, Piclamilast and Arofylline to the female host. In another aspect, the invention provides for specific administration of the phosphodiesterase inhibitor prior to the luteal phase of the host's ovulatory cycle.
Patent IL-176455-A0 (IL)
Title: Method for the production of a thermoplastic optical conduit
IPC: B29D11/00
Filed: 2006-06-21
Abstract: A method of fabricating a light duct includes making the light duct as a single piece by injection molding a thermoplastic material in a mold (1) presenting a cavity of shape identical to that of the duct, the injection taking place through a feed orifice disposed on one side of said cavity over a face that is substantially parallel to the plane defined by axes (A-A′, B-B′), the feed orifice presenting a height h lying in the range 0.2 Hmax and Hmax, and a length l lying in the range 0.2 Lmoy and 0.8 Lmoy, the thermoplastic material being injected at a rate lying in the range 400 mm3/s to 1500 mm3/s.
Patent AP-2001002083-A0 (AP)
Title: Audio/video signal redistribution system.
Inventor: JEFFERY ROSS A
IPC: H04M11/08
Filed: 1999-07-30
Abstract: A system for redistributing a multiple input audio/video signals having a redistributing device equipped to receive signals in multiple formats and redistribute a selected signal to a user's premises over conductors, preferably existing twisted-pair telephone wire. The redistributing device is in interactive communication with a communications interface located in the user's premises which receives user-input contro signals and contains switching circuitry which routes the selected signal to the user's premises where it is received by the receiving unit such as a television receiver. A single redistributing device services an entire multi-user network from a common distribution point, and services multiple users independently. The system of the invention does not interfere with normal use of the telephone network, so users can interactively access services provided by the system and use the telephone at the same time.
Patent MC-2446-A1 (MC)
Inventor: LAUDINET C
IPC: F16B/
Filed: 1997-01-23
Abstract: In the foregoing summary, the inventor has described a servo-control device for controlling automotive vehicle clutches.This servo-control device is realised from a differential actuation system (differential comparator) not having a control device for overlap of distribution elements of the distributor.The inventor describes a method of control of overlap of distribution elements of the distributor, and claims the rights to the method.
Patent LU-86135-A1 (LU)
Title: Bromocriptine or its salt in lyophilised compsn. - for reconstitution in isotonic vehicle for ocular instillation
IPC: A61K9/19
Filed: 1985-10-23
Abstract: A lyophilisate capable of reconstitution in an isotonic vehicle to provide a stable formulation suitable for occular instillation comprises as active ingredient bromocriptine and one of its acid-addition salts.
Patent LU-87614-A1 (LU)
Inventor: NOLTE DOUGLAS A
IPC: E05B63/00
Filed: 1989-10-26
Abstract: A window lock having plural ramped 100, 110 keepers for a window sash and plural rollers 112 movably associated with a slider 40 mountable on a window frame to provide multi-point locking. The actuating mechanism provides for toggle positioning of the rotatable actuating handle 12 and associated drive link 70 to prevent movement of the lock mechanism by outside forces other than the handle. <IMAGE>
Patent MA-21607-A1 (MA)
Inventor: ITZHAK BARNOACH
IPC: B29C48/153
Filed: 1989-08-01
Abstract: Apparatus for forming a plastics coated metal tube comprising means for forming a continuous strip of metal into a U-shape and a forming sleeve for folding the strip into an overlapping tube. A mandrel (23) is also provided which extends through the forming sleeve and through a locating sleeve (30). The locating sleeve (30) centralises the tube as it passes over the mandrel and welding means are provided for welding the overlapping tube as it passes through the locating sleeve (30). According to the invention, the welding means comprises an ultrasonic welding wheel (32) and drive means for the welding wheel, the drive means being capable of driving the welding wheel (32) at a peripheral speed identical to the speed at which the overlapping tube is drawn past the wheel.
Patent MA-22531-A1 (MA)
Inventor: DJELOUH SALAH
IPC: A01M29/32
Filed: 1992-05-22
Abstract: Device for protection against birds, characterised in that:   - the support has the shape of a tong (2) equipped with a groove (5) having an inverted T shaped cross-section, and opens up, - the spikes (4) are needles equipped with a head (7) which is positioned in the groove (5).   <IMAGE>
Patent MA-37685-A1 (MA)
Title: Composés acide diméthyl-benzoïque inhibiteurs selectifs de l'ep4 pour utilisation dans le traitement d'etats pathologiques inflammatoires tels que l'arthrite
Inventor: BLANCO-PILLADO MARIA-JESUS
IPC: C07D401/04
Filed: 2014-12-23
Abstract: La présente invention concerne un composé de formule ii : dans laquelle a représente : * r1 représente ch3, cf3, ou f ; * r2 représente h, ch3, ou f ; * r3 représente ch3, och3, oh, f ; r4 représente oh ou ch2oh ; et * x représente ch ou n ; ces composés sont des inhibiteurs sélectifs de l'ep4 et sont utiles dans le traitement d'états pathologiques inflammatoires tels que l'arthrite.
Patent MA-44553-A1 (MA)
Title: Revêtement céramique-métal pour tubes d'échangeur de chaleur de récepteur solaire central et ses procédés de préparation
Inventor: BOSSMANN HANS-PETER
IPC: C23C28/02
Filed: 2017-07-12
Abstract: L'invention concerne des revêtements céramique-métal (11) pour des tubes d'échangeur de chaleur (10) d'un récepteur solaire central (120), et ses procédés de préparation. Les revêtements céramique-métal (11) comprennent au moins une phase céramique dispersée dans une matrice métallique et sont disposés le long des tubes d'échangeur de chaleur (10) afin d'améliorer le transfert de chaleur et de réduire l'oxydation des tubes d'échangeur de chaleur (10). L'invention concerne également des procédés de prépara
Patent MA-47392-A1 (MA)
Title: Bis-octahydrophénanthrène carboxamides et leurs conjugués protéiques
Inventor: MURPHY ANDREW J
IPC: C07C233/90
Filed: 2018-05-09
Abstract: L'invention concerne des composés, des compositions et des méthodes pour le traitement de maladies et de troubles associés au récepteur hépatique x, notamment les bis-octahydrophénanthrène carboxamides et les conjugués protéiques de médicaments (par exemple, anticorps) de ceux-ci.
Patent MA-53037-A1 (MA)
Title: Encre de securite luminescente a double emission et son utilisation
Inventor: MOUDAM OMAR
IPC: C09K11/77
Filed: 2021-04-07
Abstract: L‘invention se rapporte à une encre de sécurité luminescente comprenant un composite formé d’au moins un premier, respectivement au moins un second composant exerçant chacun un décalage luminescent descendant sous l’effet d’une unique excitation lumineuse, donnant lieu chacun à une émission de lumière distincte l’une de l’autre dans le spectre visible, l’émission lumineuse du second composant persistant au-delà de la suppression de l’excitation lumineuse unique. Applications comme marqueur d’authenticité, comme indicateur ou sceau de qualité, comme dispositif anti-fraude ou comme dispositif anti-contrefaçon.
Patent MA-53570-A1 (MA)
Title: Procédé de fabrication de comprimés à ingestion facile contenant un extrait sec de feuilles de ginkgo biloba
Inventor: HERRMANN JOACHIM
IPC: A61K9/20
Filed: 2020-01-08
Abstract: La présente invention concerne un procédé de fabrication d’un comprimé à désintégration rapide dont la durée de désintégration est supérieure à 15?Minutes, d’administration par voie orale d’un extrait sec de feuilles de ginkgo biloba, le poids total du comprimé étant compris entre 150 et 300?Mg pour 100?Mg de l’extrait de ginkgo présent. L’invention concerne également des comprimés à désintégration rapide contenant un extrait sec des feuilles de ginkgo biloba, lesquels comprimés sont plus faciles à ingérer que les comprimés utilisés à ce jour, en raison de leur petite taille. Selon un mode préféré de réalisation, les comprimés ne contiennent pas de lactose, et sont donc bien tolérés.
Patent UY-25710-A1 (UY)
Title: Sistema de entrega controlado de droga administrado oralmente, que provee control temporal y espacial
Inventor: STANIFORTH JOHN N
IPC: A61K9/52
Filed: 1999-09-14
Abstract: Composicion farmaceutica en forma de tabletas o capsulas que provee una combinacion de control temporal y espacial de la liberacion de una droga a un paciente para resultados terapeuticos efectivos. Esta composicion comprende una droga, un componente generador de gas, un agente dilatador, un agente viscoso y opcionalmente un polimero formador de gel. La composición farmacéutica donde la droga es seleccionda del grupo que esta compuesto por drogas terapéuticas, quimioterapéuticas, antibióticas, anticancerígenas, antimicosas, antifibrales, antiulceras, antivirales, antigota, cardiovasculares, antiflamatorio, respirarorias, inmunosupresoras, y reductoras de grasa, en dicha composición el generador de gas es un silfito, un carbonato, o una sal de bicarbonato, el agente dilatador comprende un superdesintegrador, el agente viscoso contiene una goma de carbohidratos, y el polimero formador comprende una sal soluble en agua de por lo menos un ácido poliurónico. Ini cialmente el agente viscoso y luego el gas el polimero formador de gel, forman una matriz de gel hidratada que ocluye el gas, causando que la tableta o cápsula floten para ser retenidas en el estomago o en la parte alta del intestino delgado (control espacial). Al mismo tiempo la matriz de gel hidratado crea un camino de difusión tortuoso para la droga, lo que resulta en un liberación sostenida de la droga (control temporal). Una formulación, preferida, de ciprofloxacin administrada una sola vez al día comprende 69,9% de base de ciprofloxacin, 0,34% de alginato de sodio, 1,03% de goma jántica, 13,7% de bicarbonato de sodio, 12,1% de polivinilpirrolidona de enlace cruzado, y opcionalmente otros excipientes farmacéuticos, la formulación está en forma de tabletas recubiertas o no, o en cápsulas.
Patent UY-26945-A1 (UY)
Title: Alcanosulfonatos de fenoxifenilo
Inventor: HEIL DR MARKUS
IPC: C07C311/09
Filed: 2001-09-24
Abstract: La invención se refiere a nuevos alcanosulfonatos de fenoxifenilo, a procedimientos para su preparación, a su uso para la preparación de medicamentos para el tratamiento y/o la profilaxis de enfermedades, especialmente para el tratamiento de dolencias y afecciones neurodegenerativas.
Patent UY-27899-A1 (UY)
Title: Producto absorbente
Inventor: AMP JOHNSON
IPC: A61F13/15
Filed: 2003-07-21
Abstract: El producto, presenta como ventajas una mayor capacidad de absorción y una mayor velocidad de transporte de fluidos, incluso después de descargas sucesivas, continuando para absorber y conducir rápidamente los fluidos corporales desde la región de descarga hasta el núcleo absorbente, 3, permitiendo su almacenamiento correcto; también, la capa de transferencia, 5, ofrece alta resistencia mecánica reduciendo la ocurrencia de colapso estructural de núcleo absorbente, 3 debido a la humedad combinada con la aplicación de fuerzas; además todas estas ventajas se logran manteniendo un costo de fabricación reducido para el producto absorbente, maximizando su potencial de penetración en el mercado.
Patent UY-28739-A1 (UY)
Title: Nuevos compuestos de piridin-2-ona útiles como inhibidores de trombina
Inventor: INGHARDT TORD
IPC: C07D401/14
Filed: 2005-02-04
Abstract: Se proporciona un compuesto de fórmula I en donde la línea punteada, R1, R2, R3a, R3b, A, D, E, G y L tienen los significados proporcionado en la memeoria descriptiva, siendo dichos compuestos útiles como inhibidores competitivos de serinproteasas similares a al tripsina ( o como profármacos de los mismos), tal como la trombina, y por lo tanto, en particular, en el tratamiento de condiciones en dondenla inhibición de la trombina resulta beneficiosa (por ejemplo, condiciones tales como tromboembolismos en donde resulte necesaria la inhibición de la trombina y/o condiciones para las cuales se indica una terapia anticoagulante).
Patent UY-29498-A1 (UY)
Title: Derivados de aminoácidos
Inventor: GRAHAM SHELLEY RENE
IPC: A61P3/14
Filed: 2006-04-26
Abstract: Derivados de Aminoácidos La presente invención se refiere a un método para tratar el dolor usando un compuesto de fórmula en la que R1, R2, R3 y R4 son como se han definido anteriormente. La invención también se refiere a ciertos nuevos derivados de fórmula (I).
Patent UY-30690-A1 (UY)
Title: Filtro funcional de pajita para beber
Inventor: BARON PETER
IPC: A47G21/18
Filed: 2007-11-06
Abstract: Un sistema dispensador que incluye un tubo alongado 9A, un receptáculo 1 que contiene un primer ingrediente activo 4, un filtro 10 que incorpora una membrana curva 42 y un segundo ingrediente activo incluido en el tubo entre el receptáculo y el segundo filtro. El líquido vehículo atraviesa la pajita primero y segundo se dispersan progresivamente en el líquido vehículo en la pajita en el punto de consumo.
Patent ES-177870-A1 (ES)
Title: Mejoras en o relativas a sistemas para contar impulsos eléctricos
IPC: H03K23/00
Filed: 1947-05-03
Abstract: Sistema para contar impulsos eléctricos caracterizado por un dispositivo contador eléctrico en el que la operación de contar se efectúa por medio de termistors.