baber/WOPTO huggingface dataset:
Patent NZ-553841-A (NZ)
Title: Method for enantioselective preparation of sulfoxide derivatives
Inventor: COHEN AVRAHAM
IPC: C07C315/02
Filed: 2005-10-05
Abstract: Disclosed is a method for the enantioselective preparation of sulfoxide derivative or their salts, represented by formula (Ia), wherein A is an optionally substituted pyridinyl group and B is a heterocyclic group comprising an imidazo-pyridinyl group, wherein an enantioselective oxidation of a sulphide of formula (I), using an oxidizing agent in the presence of a titanium(IV)-based catalyst and a chiral ligand comprising a cyclic beta- or gamma-amino-alcohol, in an organic solvent, followed as necessary by a salification by a base.
Patent NZ-572769-A (NZ)
Title: Apparatus for producing barrel stave including sensing means and cutting means
Inventor: ROBERTS IAN
IPC: B27H3/02
Filed: 2007-05-17
Abstract: Disclosed is an apparatus for producing a barrel stave for use in a barrel of predetermined diameter. The apparatus includes a sensing means that is used to measure the width of a stave work piece along the entire length of the stave work piece. There is a cutting means that is adapted to cut the stave work piece as a function of the width of the stave work piece along its entire length. The cutting means is also adapted to cut a longitudinal side edge of the stave work piece at an angle and a depth that is determined as a function of the barrel diameter. The resultant side edge is adapted for flush abutment at an inner surface of the barrel with the longitudinal side edge of an adjacent stave formed by the apparatus.
Patent NZ-576825-A (NZ)
Title: A reflector apparatus suitable for roads and vehicles or as an ornament
Inventor: LEVON LEIF
IPC: E01F9/619
Filed: 2009-05-07
Abstract: A safety reflector suitable for roads and vehicles, able to receive external ambient light 7 or other remote energy sources from at least two directions in order to luminesce or fluoresce a body 3 lodged in a tapered section between at least two reflectors 1 placed in close proximity to one another. The reflector may have lenses fitted in or near its tapered or converging end. Preferably the reflector is able to emit light at 360 degrees even when received light appears from one direction only. The reflector may be equipped with auxiliary diode lights powered by solar cells or transferring energy from a distantly located primary coil and a secondary coil housed within a safety device (not shown).
Patent NZ-581540-A (NZ)
Title: 5-Chloro-N-{ [2-oxopyridin-1(2H)-yl]-phenyl} -2-oxo-1,3-oxazolidin-5-yl]methyl} thiophene-2-carboxamide derivatives
Inventor: KRUGER JOACHIM
IPC: A61K31/4439
Filed: 2008-06-07
Abstract: Disclosed are 5-chloro-N-{ [2-oxopyridin-1(2H)-yl]-phenyl} -2-oxo-1,3-oxazolidin-5-yl]methyl} thiophene-2-carboxamide derivatives as represented by the general formula (I), wherein R1 represents chlorine, trifluoromethoxy, methyl, ethyl, n-propyl, methoxy, methoxymethyl or ethoxymethyl; R2 represents hydrogen or methyl, and R3 represents a substituted aminoalkyl group as defined herein. Further disclosed is a medicament which comprises a compound as defined above in combination with an inert nontoxic pharmaceutically acceptable auxiliary for the treatment and/or prophylaxis of sepsis, systemic inflammatory syndrome (SIRS), septic organ dysfunction, septic organ failure and multi organ failure, acute respiratory distress syndrome (ARDS), acute lung injury (ALI), septic shock and/or disseminated intra vascular coagulation.
Patent NZ-584101-A (NZ)
Title: Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Inventor: JACKSON SIMON MARK
IPC: A61K39/395
Filed: 2008-08-22
Abstract: Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
Patent NZ-585261-A (NZ)
Title: Pyrrolo [2, 3 -d] pyrimidin derivatives as protein kinase b inhibitors
Inventor: JOHNSON PAUL DAVID
IPC: A61K31/519
Filed: 2008-10-09
Abstract: Disclosed are pyrrolo [2,3-D] pyrimidin derivatives of Formula (I), wherein the substituents are as defined in the specification, and their use in the treatment of cancer including breast cancer. Also disclosed is a process for the preparation of compounds of Formula (I).
Patent NZ-587052-A (NZ)
Title: Method for instantaneous peak level management and speech clarity enhancement
Inventor: SMITH DESMOND ARTHUR
IPC: G10L15/20
Filed: 2009-01-29
Abstract: A method for improving the clarity of acoustic speech signals comprises continuously measuring the average level of an input signal; applying at least one gain value to the speech signal by a predetermined factor; and simultaneously clipping the peak values of the input speech signal by a pre-calculated amount. The speed of the clipping of the peak values is based upon the measured average level of the input signal; and whereby the soft high frequency unvoiced spoken components are perceptually enhanced.
Patent NZ-587804-A (NZ)
Title: Authentication system for inductive power transfer system
Inventor: TETLOW STEVEN DOUGLAS
IPC: H01F38/14
Filed: 2010-09-06
Abstract: Disclosed is an inductive power transfer system (IPT) node including a communication circuit for receiving a communication signal from another component of an IPT system. Also included is a processing means for detecting component authentication information or a component control instruction in the communication signal.
Patent NZ-596205-A (NZ)
Title: Derivatives of n-acyl-n'-phenylpiperazine useful (inter alia) for the prophylaxis or treatment of diabetes
Inventor: MCGEE KEVIN FRANCIS
IPC: C07D209/42
Filed: 2010-04-16
Abstract: The present disclosure relates to a compound represented by the formula wherein each symbol is as defined in the present specification, which has a superior RBP4-lowering action and is useful as a pharmaceutical composition for the prophylaxis or treatment of a disease or condition mediated by an increase in RBP4 such as diabetes and age-related macular degeneration. Examples of the disclosed compounds include N-{ [4-(2-tert-Butylphenyl)piperazin-1-yl]carbonyl} glycine, 3-[4-(2-tert-Butylphenyl)piperazin-1-yl]-3-oxopropanoic acid and [4-(2-tert-Butyl-4-chlorophenyl)piperazin-1-yl](oxo)acetic acid.
Patent NZ-597706-A (NZ)
Title: Daylighting devices and methods with auxiliary lighting fixtures
Inventor: JASTER PAUL AUGUST
IPC: E04D13/00
Filed: 2010-08-11
Abstract: 597706 A daylighting apparatus 10 comprises a tube 24 having a sidewall with a reflective interior surface, the tube 24 disposed between a transparent cover 20 configured to receive daylight and a diffuser 26 configured to be positioned inside a target area of a building. The tube 24 is configured to direct the daylight transmitted through the transparent cover 20 towards the diffuser 26. An auxiliary light fixture comprises a lamp 30 configured to provide illumination to the interior of the tube by emitting a cone of light. The lamp 30 is positioned such that light exiting the lamp along the angular centre of the cone of light propagates such that the light is incident on a surface other than the diffuser before propagating to the diffuser. A light control surface 32 extends from the sidewall of the tube 24 and is configured to redirect at least a portion of light emanating from the lamp 30 towards the diffuser 24. The light control surface 32 comprises a top edge and a base perimeter, the top edge abutting the sidewall of the tube and the base perimeter being substantially coplanar with a base of the lamp.
Patent NZ-598508-A (NZ)
Title: Method of preparing plant-derived proteins
Inventor: VEZINA LOUIS-PHILIPPE
IPC: C12N15/82
Filed: 2010-09-21
Abstract: 598508 Disclosed is a method of preparing plant derived proteins, or protein suprastructures, comprising: a. obtaining a plant or plant matter comprising plant-derived proteins or suprastructure proteins, b. digesting the plant matter using a cell wall degrading multi-component enzyme mixture comprising one or more than one cellulase to produce a digested fraction; c. filtering the digested fraction to produce a filtered fraction and recovering the plant-derived proteins, or suprastructure proteins, from the filtered fraction, wherein the protein suprastructures have a molecular weight from about 75 to about 1500 kDa.
Patent NZ-599794-A (NZ)
Title: Direct current circuit breaker with parallel connection of main breaker, auxiliary breaker and non-linear resistor
Inventor: HAFNER JURGEN
IPC: H01H9/00
Filed: 2009-11-16
Abstract: 599794 Disclosed is a device (13) for breaking a direct electrical current flowing through a power transmission or distribution line (14). The device (13) is comprised of a parallel connection of a main breaker (8) and a non-linear resistor (11). The main breaker (8) is comprised of at least one power semiconductor switch of a first current direction (4). The device (13) is further comprised of a series connection of a high speed switch (10) and an auxiliary breaker (9). The high speed switch (10) is comprised of at least one mechanical switch. The auxiliary breaker (9) has a smaller on resistance than the main breaker (8) and is comprised of at least one power semiconductor switch of the first current direction (4). The series connection of the high speed switch (10) and auxiliary breaker (9) is connected in parallel to the parallel connection of the main breaker (8) and the non-linear resistor (11). The device (13) is adapted to open the auxiliary breaker (9) upon receipt of an auxiliary breaker signal prior to a decision to open the main breaker (8) having been taken.
Patent NZ-600758-A (NZ)
Title: Antibodies to human programmed death receptor pd-1
Inventor: VAN EENENNAAM HANS
IPC: A61K39/395
Filed: 2008-06-13
Abstract: NZ 600758 Disclosed is an isolated antibody or antibody fragment, as defined in the specification, which binds to human programmed death receptor-1 (PD-l). The disclosed antibody or antibody fragment blocks binding of human PD-L1 and human PD-L2 to human PD-1. Also disclosed is the use of said antibody for the preparation of a medicament, wherein the medicament is for the treatment of cancer or an infection or an infectious disease.
Patent NZ-602103-A (NZ)
Title: Low emissivity and emi shielding window films
Inventor: VAN NUTT CHARLES N
IPC: C08J7/044
Filed: 2011-02-28
Abstract: Disclosed herein is a low emissivity and EMI shielding transparent composite film typically for use in association with window glazing and comprising a transparent film substrate having on one side thereof an underlayer of abrasion resistant hardcoat material with at least one infrared reflective layer covering the underlayer, typically a metallic layer which may be encased in metal oxide layers, which is then covered with a thin external protective top coat of a cured fluorinated resin.
Patent NZ-603896-A (NZ)
Title: 3-amino-5,6-dihydro-1h-pyrazin-2-one derivatives useful for the treatement of alzheimer's disease and other forms of dementia
Inventor: TRABANCO-SUAREZ ANDRES AVELINO
IPC: A61K31/495
Filed: 2011-06-27
Abstract: Abstract - 603896 Disclosed are 3-amino-5-[3-(aryl / heteroaryl)-phenyl]-5,6-dihydro-1H-pyrazin-2-one derivatives as represented by the general Formula (I) or stereoisomeric forms thereof, wherein R1 is selected from the group consisting of hydrogen, alkyl, mono- and polyhalo-alkyl, aryl and heteroaryl; R2 is selected from the group consisting of hydrogen, alkyl, mono- and polyhalo-alkyl, aryl and heteroaryl; X1, X2, X3, X4 are independently C(R3) or N, provided that no more than two thereof represent N; each R3 is selected from the group consisting of hydrogen, halo, alkyl, mono- and polyhalo-alkyl, cyano, alkyloxy, mono- and polyhalo-alkyloxy; L is a bond or -N(R4)CO-, wherein R4 is hydrogen or alkyl; Ar is homoaryl or heteroaryl; wherein homoaryl is phenyl or phenyl substituted with one, two or three substituents selected from the group consisting of halo, cyano, alkyl, alkyloxy, mono and polyhalo-alkyl; heteroaryl is selected from the group consisting of pyridyl, pyrimidyl, pyrazyl, pyridazyl, furanyl, thienyl, pyrrolyl, pyrazolyl, imidazolyl, triazolyl, thiazolyl, thiadiazolyl, oxazolyl, and oxadiazolyl, each optionally substituted with one, two or three substituents selected from the group consisting of halo, cyano, alkyl, alkyloxy, mono- and polyhalo-alkyl; or an addition salt or a solvate thereof. Representative compounds include 3'-(6-amino-2,4-dimethyl-5-oxo-2,3,4,5-tetrahydropyrazin-2-yl)-biphenyl-3-carbonitrile, 3-amino-5-[3-(5-methoxy-pyridin-3-yl)-phenyl]-1,5-dimethyl-5,6-dihydro-1H-pyrazin-2-one, 5-chloro-pyridine-2-carboxylic acid [3-(6-amino-2,4-dimethyl-5-oxo-2,3,4,5-tetrahydro-pyrazin-2-yl)-phenyl]-amide, 5-chloro-pyridine-2-carboxylic acid [3-(6-amino-2,4-dimethyl-5-oxo-2,3,4,5-tetrahydro-pyrazin-2-yl)-phenyl]-amide, 5-amino-3-(2,4-difluoro-biphenyl-5-yl)-1,3-dimethyl-2H-pyrazin-6-one, 5-amino-3-[2,4-difluoro-5-(5-methoxy-3-pyridyl)phenyl]-1,3-dimethyl-2H-pyrazin-6-one, 5-amino-3-(2,4-difluoro-5-pyrimidin-5-yl-phenyl)-1,3-dimethyl-2H-pyrazin-6-one, 5-chloro-pyridine-2-carboxylic acid [3-(6-amino-2,4-dimethyl-5-oxo-2,3,4,5-tetrahydro-pyrazin-2-yl)-4-fluoro-phenyl]-amide, 5-amino-1,3-dimethyl-3-(biphenyl-3-yl)-2H -pyrazin-6-one and 5-amino-1,3-dimethyl-3-(3-(pyrimidin-5-yl)phenyl)-2H-pyrazin-6-one. Further disclosed is a pharmaceutical composition comprising a therapeutically effective amount of a compound as defined above and a pharmaceutically acceptable carrier for the treatment of Alzheimer's disease, mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease and dementia associated with beta-amyloid.
Patent NZ-619294-A (NZ)
Title: Hcv genotype 4 replicons
Inventor: DELANEY WILLIAM E IV
IPC: G01N33/569
Filed: 2012-07-05
Abstract: Disclosed is a genotype 4a hepatitis C viral (HCV) RNA construct comprising a S’NTR, an internal ribosome entry site (IRES), a sequence encoding NS4A, and a 3 ‘NTR, wherein the RNA construct further comprises a mutation, as compared to a wild-type NS4A HCV 4a sequence, wherein the mutation is selected from Q34K, Q34R, or ES2V in NS4A, or combinations thereof. Also disclosed is an NS4A protein of HCV genotype 4a that comprises a mutation, as compared to the wild-type HCV 4a NS4A protein, selected from Q34K, Q34R, or E52V or combinations thereof.
Patent NZ-625636-A (NZ)
Title: Novel pyrrole derivatives
Inventor: ANDREW PETER WILLIAM
IPC: C07D417/04
Filed: 2012-12-05
Abstract: The disclosure relates to pyrrole derivative compounds of formula (I) which are cytolysin inhibitors, wherein R1, R2, R3, R4a and R4b are as defined in the specification. These compounds are suitable for use in the treatment of bacterial infections caused by bacteria selected from Streptococcus spp. (e.g. Streptococcus pneumoniae, Group A Streptococci or Streptococcus suis), Clostridium spp. (e.g. Clostridium perfringens), Listeria spp. (e.g. Listeria monocytogenes) or Bacillus spp. (e.g. Bacillus anthracis) which produce pore-forming toxins, such as cholesterol dependent cytolysins. These compounds are also suitable for the treatment of conditions selected from gas gangrene, gastrointestinal anthrax, inhalational anthrax, porcine meningitis, encephalitis, septicaemia/bacteraemia and pneumonia which are caused by bacteria other than pneumococcus.
Patent NZ-629873-A (NZ)
Title: Fishing tackle holder
Inventor: MARTYN JAMES WALLACE
IPC: A01K97/08
Filed: 2013-09-18
Abstract: A fishing tackle holder for removable attachment to a fishing rod comprising a tip and a butt, the fishing tackle holder comprising at least one containment region bounded by one or more side walls and one or more lower walls, and having an opening of sufficient size to receive fishing tackle into the containment region; wherein, when attached to the fishing rod, the fishing tackle holder is configured to be positioned such that the opening faces substantially along the fishing rod in the direction of the tip.
Patent NZ-631134-A (NZ)
Title: Motor drive system for respiratory apparatus
Inventor: SHADIE TIMOTHY NICHOLAS
IPC: H02M3/155
Filed: 2014-06-20
Abstract: A respiratory apparatus comprising a power supply 4210 coupled to a bus 4422, and a blower configured to generate a flow of breathable gas. The blower includes a motor 4144 powered by the power supply via the bus 4422. The motor 4144 generates energy at certain times. There is a transient absorption diode circuit 4400 on the bus 4422 between the motor and the power supply to absorb the energy generated. A second invention is a fault mitigation circuit.
Patent NZ-700218-A (NZ)
Title: Aqueous herbicide concentrates containing fatty acid alkyl esters, fatty acid amides, or triglyceride fatty acid esters and methods of use
Inventor: LIU LEI
IPC: A01P13/00
Filed: 2013-03-14
Abstract: Aqueous herbicide concentrates containing a herbicide (such as an auxinic herbicide), a surfactant, and a fatty acid alkyl ester, a fatty acid amide, and/or a triglyceride fatty acid ester and the use of aqueous herbicide spray mixtures incorporating such concentrates are described. The aqueous herbicide concentrates described herein include from 5 to 90 weight percent of a water soluble salt of a herbicide, from 0.1 to 20 weight percent of a surfactant, and from 0.1 to 20 weight percent of a fatty acid alkyl ester, fatty acid amide, and/or a triglyceride fatty acid ester. The aqueous herbicide concentrate is a transparent, homogeneous liquid that forms a stable emulsion upon dilution into a spray solution.
Patent NZ-700580-A (NZ)
Title: Compounds useful as inhibitors of atr kinase and combination therapies thereof
Inventor: POLLARD JOHN ROBERT
IPC: A61P35/00
Filed: 2013-04-05
Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase and combination therapies thereof. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I:wherein the variables are as defined herein.
Patent NZ-700952-A (NZ)
Title: Portable drill press
Inventor: NOWLAND CLAUDE ERNEST
IPC: B25H1/10
Filed: 2013-03-23
Abstract: A drill press comprises a hollow pillar with a base, a holder for a drill slidably mounted on the pillar and a clamp integral to the pillar for clamping the base to a work piece so that the drill is guided to the work piece. The clamp can be a G clamp with a jaw held by an arm which engages a threaded shaft housed in the pillar so that movement of the shaft raises and lowers the arm and the jaw. The drill press provides for a combination of a slidable holder and a moveable clamp to improve the versatility of the press allowing it to be used on a variety of different work pieces.
Patent NZ-701128-A (NZ)
Title: Conjugates for the prevention or treatment of nicotine addiction
Inventor: PRYDE DAVID CAMERON
IPC: A61K31/465
Filed: 2011-06-03
Abstract: Disclosed a hepten nicotine derivatives of formula (I). Also disclosed are conjugates comprising a moiety of formula (I) and an optionally modified carrier protein selected from bacterial toxoids, immunogenic substances, viruses, virus-like particles, protein complexes, proteins, polypeptides, liposomes and immuno-stimulating complexes.
Patent NZ-702803-A (NZ)
Title: Cns delivery of therapeutic agents
Inventor: SHAHROKH ZAHRA
IPC: A61P25/28
Filed: 2011-06-25
Abstract: Disclosed is a composition for intrathecal administration comprising a replacement enzyme for treating a lysosomal storage disease associated with reduced level or activity of a lysosomal enzyme, wherein the replacement enzyme is present in the composition at a concentration at or greater than about 10 mg/ml, the composition comprises phosphate at a concentration no greater than 50 mM.
Patent NZ-702943-A (NZ)
Title: Humanized il-7 rodents
Inventor: MURPHY ANDREW J
IPC: C07K14/54
Filed: 2013-06-14
Abstract: The present invention relates to a genetically modified rodent comprising in its germline a replacement of rodent IL-7 exons with human IL-7 exons 2 through 6 to form a humanized IL-7 gene, wherein the replacement is at an endogenous rodent IL-7 locus and the resulting modified rodent IL-7 locus lacks rodent animal IL-7 exons 2, 3, 4 and 5, and wherein the humanized IL-7 gene is under control of endogenous rodent IL-7 5’ regulatory elements. The present invention also relates to a method for making a rodent with a humanized IL-7 gene, comprising modifying the germline of the rodent by replacement of rodent IL-7 exons with human IL-7 exons 2 through 6 to form a humanized IL-7 gene, wherein the modification is at an endogenous rodent IL-7 locus and wherein the humanized IL-7 gene is under control of endogenous rodent IL-7 regulatory elements. The present invention also relates to a humanized IL-7 locus comprising a replacement of rodent IL-7 exons at an rodent IL-7 locus with human IL-7 exons to form a humanized IL-7 gene, wherein the humanized IL-7 gene comprises a rodent IL-7 exon 1, a human IL-7 exon 2, a human IL-7 exon 3, a human IL-7 exon 4, a human IL-7 exon 5 and a human IL-7 exon 6, and the humanized IL-7 gene is under control of rodent IL-7 5’ regulatory elements.
Patent NZ-709394-A (NZ)
Title: Drying system
Inventor: SELBY STEPHEN
IPC: F26B21/00
Filed: 2013-12-05
Abstract: Herein disclosed is a drier for drying boards, which more evenly dries the boards, having a reduced energy requirement and a reduced spatial requirement. The drier for drying boards comprises at least one conduit for directing airflow towards one of the faces of the board. The drier is configured such that at least a portion of the airflow travels across the face of the board along the longitudinal axis of the drier, the longitudinal axis of the drier being the axis along which the board travels as it is dried.
Patent NZ-709872-A (NZ)
Title: Spiro-lactam nmda receptor modulators and uses thereof
Inventor: LOWE JOHN
IPC: C07D487/10
Filed: 2014-01-29
Abstract: Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
Patent NZ-711526-A (NZ)
Title: Low dust joint compound and method of making the same
Inventor: FERRETTI JOHN T
IPC: C04B24/26
Filed: 2010-09-13
Abstract: Disclosed herein is a joint compound or wall repair composition and the method of making the same is disclosed that reduces the amount of airborne dust emitted during traditional sanding processes. Generally, such a reduction can be achieved by combining a first binder that has a high glass transition temperature (greater than 10 degrees Celsius) and a second binder that has a low glass transition temperature (–80 degrees Celsius to 10 degrees Cesius) with conventional joint compound compositions. The first and/or second polymers may be ethylene vinyl acetate, vinyl acetate, acrylics, styrene acrylics, and polyvinyl alcohol.