baber/WOPTO huggingface dataset:
Patent DE-69532197-D1 (DE)
Inventor: WEINER B
IPC: C07K16/10
Filed: 1995-05-17
Granted: 2004-01-08
Abstract: A method for treating an individual exposed to or infected with HIV is disclosed which comprises administering to said individual a therapeutically effective amount of one or more compounds which inhibit or prevent replication of said HIV by interfering with the replicative or other essential functions of Vpr expressed by said HIV, by interactively blocking the Vpr target in human cells, and thereby preventing translocation of the Vpr/target complex from the cytosol of said human cells to the nuclei of said cells, where Vpr carries on activities essential to replication of HIV. In preferred embodiments, the compound or compounds which interactively block the target are steroid hormone receptor antagonists, glucocorticoid receptor antagonists, or glucocorticoid receptor Type II antagonists, especially mifepristone (RU-486). Pharmaceutical compositions comprising these compounds, as well as a method for identifying them and a kit for use therein, are also disclosed.
Patent DE-69534046-D1 (DE)
Inventor: PINKEL DANIEL
IPC: G16B25/00
Filed: 1995-12-08
Granted: 2005-04-07
Abstract: The present invention provides methods of determining relative copy number of target nucleic acids and precise mapping of chromosomal abnormalities associated with disease. The methods of the invention use target nucleic acids immobilized on a solid surface, to which a sample comprising two sets of differentially labeled nucleic acids are hybridized. The hybridization of the labeled nucleic acids to the solid surface is then detected using standard techniques.
Patent DE-69534187-D1 (DE)
Inventor: BOEHM WOLFGANG
IPC: A61K35/14
Filed: 1995-05-15
Granted: 2005-06-09
Abstract: A method is provided for producing a sterile and pyrogen-free column containing coupled protein for use in removing a predetermined substance from the blood of a human subject. The method abrogates sterilization of the finished protein-containing product by providing sterile and pyrogen-free raw materials at each production step. The method provides a pathogen-free, purified solution of protein which binds to a predetermined substance in human blood such as LDL or immunoglobulin. Typically, the protein is anti-human LDL immunoglobulin or anti-human Ig immunoglobulin. The method also provides a sterile and pyrogen-free column matrix material such as an agarose which is chemically activated, either using CNBr and triethylamine or using 1,1'-carbonyldiimidazole. The sterile and pyrogen-free, activated matrix material and the pathogen-free, purified protein solution are combined under aseptic conditions to effect the coupling of the protein to the matrix material, and the protein-coupled matrix material is filled under aseptic conditions into a sterile and pyrogen-free housing to produce a sterile and pyrogen-free column.
Patent DE-69602253-D1 (DE)
Inventor: RAMBAUD PASCAL
IPC: E01F15/04
Filed: 1996-02-01
Granted: 1999-06-02
Abstract: A roadside crash barrier with shock-absorbing devices (3) arranged between the crash barrier rail (1) and the supporting posts (2). Each shock-absorbing device comprises two arms (3A, 3B) arranged in a V and designed to spread apart when a force is exerted on the rail, while absorbing the related energy by means of friction between the movable parts, and optionally by plastic deformation.
Patent DE-69610438-D1 (DE)
Inventor: THOREAU PHILIPPE
IPC: G07B15/06
Filed: 1996-12-18
Granted: 2000-10-26
Abstract: A method for data transfer for various applications between a on board unit (OBU), which comprises a processor, memory means and at least one interface to an external entitiy. A sequence of commands is exchanged over the interface and processed by the OBU in order to perform the respective task according to the application of the OBU and/or the external entity. The system for data transfer comprises a macro interpreter in the OBU to receive and interpret the macros from one of its interfaces.
Patent DE-69628433-D1 (DE)
Inventor: CABRE JOAN
IPC: C07D201/16
Filed: 1996-06-27
Granted: 2003-07-03
Abstract: A process for recovering 2,2-dimethylpropanoic acid in highly pure form from a mixture of 2,2-dimethylpropanoic acid and impurities which may be obtained in the production of a beta lactam antibiotic, by degrading impurities and separating off the volatile fragments.
Patent DE-69629914-D1 (DE)
Inventor: FURUYA SHUICHI
IPC: C07D519/00
Filed: 1996-02-07
Granted: 2003-10-16
Abstract: A thienopyrimidine derivative of formula (I) is effective as a prophylactic or therapeutic agent for the prevention or treatment of several hormone dependent diseases, for example, a sex hormone dependent cancer (e.g. prostatic cancer, cancer of uterine cervix, breast cancer, pituitary adenoma), benign prostatic hypertrophy, myeloma of the uterus, endometriosis, precocious puberty, amenorrhea, premenstrual syndrome, polycystic ovary syndrome and acne vulgaris; is effective as a fertility controlling agent in both sexes (e.g. a pregnancy controlling agent and a menstrual cycle controlling agent); can be used as a contraceptive of male or female, as an ovulation-inducing agent of female; can be used as an infertility treating agent by using a rebound effect owing to a stoppage of administration thereof; is useful as modulating estrous cycles in animals in the field of animal husbandry, as an agent for improving the quality of edible meat or promoting the growth of animals; and is useful as an agent of spawning promotion in fish.
Patent DE-69635959-D1 (DE)
Inventor: JAVITT DANIEL C
IPC: A61K31/22
Filed: 1996-12-05
Granted: 2006-05-11
Abstract: The amino acid glycine in an administered amount of above 0.4 g/Kg/day is used for treating symptoms of psychosis and of schizophrenia.
Patent DE-69701138-D1 (DE)
Inventor: BEUDON DIDIER
IPC: F24F9/00
Filed: 1997-04-09
Granted: 2000-02-17
Abstract: PCT No. PCT/FR97/00626 Sec. 371 Date Oct. 26, 1998 Sec. 102(e) Date Oct. 26, 1998 PCT Filed Apr. 9, 1997 PCT Pub. No. WO97/40325 PCT Pub. Date Oct. 30, 1997A fabric sheath (1) for the close protection of the conveyance of sensitive products by sterilized air stream diffusion, in particular in a substantially vertical direction is formed by a sealed wall (2) and a porous wall (3) extending longitudinally and axially along the sheath, the sheath defining a sterilized air supply duct (9). It comprises means (4) extending longitudinally along the sheath that ensure median sterilized air diffusion at a higher speed. The invention also features a washable or disposable laminar-flow hood, comprising a fabric sheath bounded at each end by a plane perpendicular to the axis of the fabric sheath.
Patent DE-69711274-D1 (DE)
Inventor: SUZUKI TATSUO
IPC: B60C27/00
Filed: 1997-06-27
Granted: 2002-05-02
Abstract: A fastening device (10a) for a tire slip preventing apparatus comprising a fastening band (20a) in which a non-extensible rope (21a) and a rubber band (25a) are endlessly connected to each other, and a fastening buckle (30a) having a pair of hooks, an engagement part (31a) and a cleat (32a) supported for pivotal motion, the fastening band being formed into a double loop shape (Li,Lo), a folded portion at one end of the fastening band being connected to the engagement part (31a) of the fastening buckle (30a) with a folded portion (22a) at the other end of the fastening band being passed over the cleat (32a) so that the fastening band forms an outer circumferential loop (Lo) and an inner circumferential loop (Li) to constitute the fastening device (10a) having a non-reversible self-lock mechanism in which the cleat (32a) is pivoted to clamp the folded portion (23a) around the cleat by a tension of the inner circumferential loop (Li), and the tire slip preventing apparatus being arranged in such a manner that joining portions at both ends of an anti-slip body wrapped around an outer circumference of a tire are connected to each other by the pair of hooks (36a,37a) so as to pass the fastening band along an edge of the anti-slip body on an outer surface of the tire, wherein the fastening device is constituted as a pair of fastening devices for right and left tires as viewed in the direction of vehicle travel and the pair of fastening devices are opposite to each other in the arrangement of the cleat (32a) and the engagement part (31a) of the fastening buckle as viewed from the outer surface of the tire so that the cleat (32a) is disposed ahead of the engagement part (31a) with respect to a tire rotation direction (R) in which a vehicle travels forward.
Patent DE-69716597-D1 (DE)
Inventor: BALIGA JAYANT
IPC: H01L29/872
Filed: 1997-05-09
Granted: 2002-11-28
Abstract: A Schottky rectifier includes MOS-filled trenches and an anode electrode at a face of a semiconductor substrate and an optimally nonuniformly doped drift region therein which in combination provide high blocking voltage capability with low reverse-biased leakage current and low forward voltage drop. The nonuniformly doped drift region contains a concentration of first conductivity type dopants therein which increases monotonically in a direction away from a Schottky rectifying junction formed between the anode electrode and the drift region. A profile of the doping concentration in the drift region is preferably a linear or step graded profile with a concentration of less than about 5x1016 cm-3 (e.g., 1x1016 cm-3) at the Schottky rectifying junction and a concentration of about ten times greater (e.g., 3x1017 cm-3) at a junction between the drift region and a cathode region. The thickness of the insulating regions (e.g., SiO2) in the MOS-filled trenches is also greater than about 1000  ANGSTROM  to simultaneously inhibit field crowding and increase the breakdown voltage of the device. The nonuniformly doped drift region is preferably formed by epitaxial growth from the cathode region and doped in-situ.
Patent DE-69719795-D1 (DE)
Inventor: BRAY JONATHAN
IPC: B65D75/58
Filed: 1997-11-19
Granted: 2003-04-17
Abstract: PCT No. PCT/GB97/03183 Sec. 371 Date May 12, 1999 Sec. 102(e) Date May 12, 1999 PCT Filed Nov. 19, 1997 PCT Pub. No. WO98/22367 PCT Pub. Date May 28, 1998A pack (1) for smoking articles such as cigarettes has a sealed enclosure of barrier material, with a resealable access aperture to the enclosure. A cover (7) over that aperture has on all its openable edges a permanently tacky surface overlapping over the barrier material there. The cover has a non-adhesive tab (10) to assist opening. An inner frame provides support to the barrier material adjacent to the aperture, allowing the adhesive cover to be pressed firmly against the barrier layer to aid resealing. The pack may be provided with or without an outer carton. If an outer carton is included, the carton may be of a generally rigid card material, and may have a flip-top configuration, may be a Laub+E,acu e+EE  box, or may have a shell-and-slide configuration. An inner frame provides support to the barrier material adjacent to the aperture, allowing the adhesive cover to be pressed firmly against the barrier layer to aid resealing. The pack may be provided with or without an outer carton. If an outer carton is included, the carton may be of a generally rigid card material, and may have a flip-top configuration, may be a Laub+E,acu e+EE  box, or may have a shell-and-slide configuration.
Patent DE-69730167-D1 (DE)
Inventor: JOHANSSON KENNETH
IPC: G01R15/14
Filed: 1997-10-08
Granted: 2004-09-09
Abstract: A device for monitoring partial discharges in high-voltage equipment (1), which has a high-voltage bushing (21, 22, 24) with a capacitive test tap (31, 33, 34). The device has an inductive current transducer in the form of a measuring coil (4) arranged around the high-voltage bushing, as well as signal-processing members (SB) which, for detection of partial discharges, are supplied with measurement signals from the coil (u) and from the test tap (i). The device further comprises a current path (36) which is coupled to the test tap and arranged outside the coil and which, together with the conductor (24) of the bushing, forms a current loop around the coil for signals (i) coming from inside the apparatus and originating from partial discharges.
Patent DE-69734127-D1 (DE)
Inventor: MENTO MARTIN FRANCO FELIX
IPC: B65F3/02
Filed: 1997-06-06
Granted: 2005-10-13
Abstract: The container (1) comprises an inverted truncated pyramid shaped body open at the top. It has a series of transverse upper bolts (4) for its lifting onto a lorry (3) provided with a crane. The lifting bolts are located inside the peripheral reinforcement of the top opening. In one of the container sides and in its base are side gyratory and extractable lifting rods mounted laterally in a bolt. Once the container is placed on the ground and the upper lifting bolts are released the container can be raised by its lower lifting bolts and tipped to allow its emptying. The upper lifting bolts are accessed through a wide upper window which communicates with a lower evacuation window. The independent lower bolts are mounted in cavities in the container corners.
Patent DE-69734512-D1 (DE)
Inventor: DRAKE CAROLINE RACHEL
IPC: C12N9/00
Filed: 1997-05-23
Granted: 2005-12-08
Abstract: A method for enhancing the expression of a tomato phytoene synthese gene in a plant while avoiding or reducing co-suppression involves the synthesis of a DNA which is altered in nucleotide sequence (SEQ ID NO:1) and is capable of expression of a protein, ideally identical to that of a protein already expressed by a DNA already present in the plant. This method ensures that sequence similarity between the two genes is reduced enough to eliminate the phenomenon of co-suppression, allowing the over-expression of a specific phytoene synthese protein.
Patent DE-69736325-D1 (DE)
Inventor: MOSSAKOWSKA EWA
IPC: C12N5/10
Filed: 1997-02-26
Granted: 2006-08-24
Abstract: A polypeptide comprising a portion of the sequence of the general formula (I): CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSG, of 6-23 amino acids in length and comprising sequence a) and/or b): a) GGRKVF, b) FELVGEPSIY multimeric and chimeric derivatives, pharmaceutiocal compositions containing them and their use in therapy.
Patent DE-69738555-D1 (DE)
Inventor: HARJU RAIMO
IPC: G01N21/25
Filed: 1997-04-22
Granted: 2008-04-24
Abstract: An optical instrument is provided for performing photoluminescence, absorption and chemical luminescence measurements from liquid and solid samples distributed on various sample support like microtitration plates. According to one embodiment of the present invention, it comprises a continuous wave lamp, a flash lamp, a novel optomechanical coupling unit, two detectors at the opposite side of the sample and a sample plate holder with full position addressable to measure every point of the sample support. <IMAGE>
Patent DE-69739360-D1 (DE)
Inventor: KAYE GORDON I
IPC: A61L2/18
Filed: 1997-04-21
Granted: 2009-05-28
Abstract: A method for safely treating and disposing of infectious biomedical waste and other hazardous materials is disclosed. The method involves alkaline hydrolysis of infectious agents contained in regulated medical waste or hazardous waste solutions. The infectious waste is immersed into a highly basic solvent which is then heated. The material containing the infectious agents is allowed to remain within the heated solvent until the hydrolyzable matter is fully digested, thereby forming a sterile solution and sterile solid waste. The sterile solution and solid waste may then be disposed of through standard means, such as in a sanitary sewage system or local landfill facility. The method also provides for the treatment of lipid soluble hazardous material contained in the regulated medical waste.
Patent DE-69809189-D1 (DE)
Inventor: MAHER DAVID P
IPC: G06Q20/00
Filed: 1998-09-21
Granted: 2002-12-12
Abstract: A method for performing electronic transactions, comprising receiving a long-term certificate, authenticating a user associated with the long-term certificate, and then sending a short-term certificate to the authenticated user. In addition, risk associated with the user can be evaluated, and this risk information, as well as other information, can be included in the short-term certificate.
Patent DE-69814477-D1 (DE)
Inventor: ANTONINI EMANUELE
IPC: A41B1/08
Filed: 1998-08-07
Granted: 2003-06-12
Abstract: The invention relates to a device permitting taking tennis balls from shorts despite the tennis shirt being out, and this without interfering with the player. It is constituted by a system of male (1,1') and female (2,2') snap members which, when snapped together, leave a free space (4), thanks to cutouts (3f,3f',3d,3d'), so that the player can take balls from the pockets of his shorts (5). The device according to the invention is particularly adapted for taking out tennis balls.
Patent DE-69822937-D1 (DE)
Inventor: NAGASE HIROSHI
IPC: C07D491/20
Filed: 1998-01-13
Granted: 2004-05-13
Abstract: The present invention provides an indolomorphinan derivative or a pharmacologically acceptable acid addition salt thereof, and an agent for curing and preventing cerebral disorders composed of the derivative and salt thereof, which is represented by the following formula (I): <CHEM> Äwherein R<1> represents cyclopropylmethyl or the like; R<2> and R<3> each represent hydroxy, methoxy, or the like; R<4> represents hydrogen, methyl, benzyl, 3-isothiocyanatopropyl, or the like; and (R<5>)m represents hydrogen, substituted benzo, or the likeÜ. It was apparent that the compounds of the present invention have the excellent effect of preventing damages of the cerebral nerve cells. Therefore, the compounds of the present invention are useful as medicines used for curing and preventing various cerebral diseases such as cerebral stroke, traumatic cerebral diseases, cerebral edema, and cerebral neurodegenerative diseases, ameliorating aftereffects thereof, and preventing the recurrence thereof by inhibiting various ischemic, hemorrhagic or traumatic cerebral disorders, and damages of the cerebral nerve cells caused by various nerve degenerations.
Patent DE-69828926-D1 (DE)
Inventor: WAMPLER RICHARD K
IPC: H02K7/14
Filed: 1998-07-13
Granted: 2005-03-17
Abstract: An implantable rotary sealless blood pump (11) is provided. The pump (11) includes a housing (12) having an inlet tube (13) on one end and an impeller casing (14) on the other end. A rotor (17) is mounted for rotation within the housing (12), with the rotor (17) having an elongated shaft portion (18) and an impeller (19) attached to the shaft portion (18). The impeller (19) is located within the impeller casing (14). Radial magnetic bearings (28,29) are carried by the shaft portion (18) and radial magnetic bearings (23,24) are carried by the housing (12) for maintaining the shaft portion (18) of the rotor (17) within the inlet tube (13) of the housing (12). A rotor motor (53) includes a plurality of permanent magnets (54) carried by the impeller (19) and a motor stator (56) including an electrically conductive coil (57) located within the housing (12). A ring of back iron (58) is carried by the impeller casing (14) to aid in completing a flux return path for the permanent magnets (54). A plurality of hydrodynamic thrust bearings are located outside of the axis of rotation of the rotor (17). The impeller (19) uses large axially thick blade sectors (49) with narrow blood channels (51) extending through the impeller (19), to minimize hemolysis and to increase the working surface of the blades (49). <IMAGE>
Patent DE-69835766-D1 (DE)
Inventor: SINGH BHAGIRATH
IPC: A61K48/00
Filed: 1998-12-11
Granted: 2006-10-12
Abstract: A peptide derived from apolipoprotein E termed apoEp1.B which includes amino acids 239-252 of the apolipoprotein E is described. The apoEp1.B peptide is a potent immune modulator that acts on a variety of immune cells. Interestingly, apoEp1.B is a dual modulator, capable of both inducing and suppressing an immune response. In particular, apoEp1.B has been shown to induce differentiation of stem cells into dendritic cells, to induce tumor cell differentiation and activation, to inhibit inflammation and to inhibit autoimmune disease.
Patent DE-69840528-D1 (DE)
Inventor: TANIGUCHI MASARU
IPC: C12N5/07
Filed: 1998-04-10
Granted: 2009-03-19
Abstract: An objective of the present invention is to provide NKT cell-activating agents, therapeutic agents for autoimmune diseases (for example, systemic lupus erythematosus, systemic sclerosis, ulcerative colitis, encephalomyelitis, multiple sclerosis and human type I diabetes), and abortifacients. The medicinal compositions according to the present invention comprise ±-glycosylceramides of the following formula (I), or a salt or a solvate thereof as an active ingredient.
Patent DE-69905433-D1 (DE)
Inventor: ROUX ROGER
IPC: F28B9/00
Filed: 1999-07-23
Granted: 2003-03-27
Abstract: The method involves feeding the hot liquid into a container (20) under low pressure to vaporize it and cool the remaining liquid. The vapor is fed to a second container for extraction of the hot gas. The first and second containers are connected by two connecting circuits which are operated repetitively to feed the material to the second container.
Patent DE-69909818-D1 (DE)
Inventor: YOO MOOHI
IPC: C07D487/04
Filed: 1999-11-10
Granted: 2003-08-28
Abstract: The present invention relates to pyrazolopyrimidinone derivatives of formula 1, their preparation method and pharmaceutical compositions containing the said derivatives. The compounds have efficacy on the treatment of impotence, one of male sexual dysfunctions with the side effects reduced.
Patent DE-69910642-D1 (DE)
Inventor: MATSUMOTO MASAKATSU
IPC: C07D493/04
Filed: 1999-03-10
Granted: 2003-10-02
Abstract: The present invention has its objects to provide a compound not only which is easy to handle, thermally stable, and high in emission efficiency, but also which can show high emission efficiency without coexisting enhancer in the system even in a protic solvent. The present invention is related to a 1,2-dioxetane derivative of general formula (I). <CHEM> Äwherein R<1>, R<2>, R<3>, R<4> and R<5> each independently represents hydrogen, alkyl or aryl; a pair of R<2> and R<3> and a pair of R<4> and R<5> may respectively be joined to each other to form a cycloalkyl group.
Patent DE-69913323-D1 (DE)
Inventor: FRITCHIE P
IPC: G01N35/00
Filed: 1999-02-10
Granted: 2004-01-15
Abstract: Methods of allocating resources in a system comprising at least two instruments are provided. In one such method, a list of tests to be performed by the system within a reaction vessel is generated. The list includes a number of reaction vessels used in performing each test to be performed by the system in a given time period. The list of tests is sorted according to the number of reaction vessels used in performing each test to be performed by the system in a given time period. A duplication percentage for the tests is determined. The duplication percentage is compared with the sorted list of tests. Resources associated with the tests are duplicated across the at least two instruments based on the comparison of the duplication percentage with the sorted list of tests such that at least one of the tests is performed by at least two of the at least two instruments.
Patent DE-69917885-D1 (DE)
Inventor: BAULT RICHARD V
IPC: A61B5/117
Filed: 1999-01-15
Granted: 2004-07-15
Abstract: A device for the authentication of a person by his fingerprints prior to an authorization of operations includes a housing having a track for sliding the finger and a sensor having a dimension less than that of the finger, disposed along the track for sliding the finger.
Patent DE-69918425-D1 (DE)
Inventor: DEAN WILLIAM
IPC: F02B29/04
Filed: 1999-04-14
Granted: 2004-08-05
Abstract: The fluid circuit arrangement comprises two circuit S. The first circuit has a heater and a heat exchange means. The second circuit has a heat exchange means, a cooler and a valve device which is responsive to a control means to bring the cooler into circuit in response to the temperature in the first circuit and optionally to other operating parameters.