baber/WOPTO huggingface dataset:
Patent EA-015861-B1 (EA)
Title: A method for industrial production of biocatalysts in the form of enzymes or microorganisms immobilized in polyvinyl alcohol gel, their use and devices for their production
Inventor: STLOUKAL RADEK
IPC: A61K9/00
Filed: 2007-03-06
Abstract: A method for the industrial production of the biocatalysts with biologically active material in the form of immobilized enzymes or microorganisms which are immobilized into the polyvinyl alcohol gel, and their use based on the fact, that the active biological material, formed by the mixture of free native or pretreated (aggregated) enzyme catalyst, or production microorganism, or part of them, and the polyvinyl alcohol gel, is used for their industrial production, the mixture is gelated and shaped in a stream of drying air at the temperature of 80°C to 15°C, considering the extent of the biologically active material, at the biocatalyst geometrical ratio of the surface to the volume kept larger than 7 mm, and consequently thus prepared biocatalysts can be cultivated or stored and then use in biotechnological processes in the conditions, which ensure given biotechnological process higher productivity, higher production and enzymatic stability, long-term and repeated usage or definable process control with consequence easy separation of the biocatalyst. The industrial production device, providing optimization of the biological carrier volume and surface in dependence on biologically active material extent, consisting of a casting mechanism (17) mounted in front of a drying channel (2), through which a continuous conveyor belt (1) runs, is equipped with at least one casting head (17) with two rows of casting needle injectors connected to a pressure tempered tank (15) and a compressor (16), the conveyor belt (1) and a drying system - the source (4) of a drying air, which is blown by means of ventilator into an air distribution system (6) with incorporated heating elements (5), which runs into the upper drying channel (2), and further the lower final drying channel (3) and a reswelling tank (7), between which a wiping and collecting device (9) is mounted, designed on the basis of mechanical wiping and high-pressure rinse, which is connected to a pipeline with integrated high-pressure pump (10) and low-pressure pump (11) running into a collecting reservoir (8) with cooling and further a rinse box (13) for continuous conveyor belt (1) final cleaning by jets connected to a low- pressure pump (14), which is connected to a rinse tank (12) by pipeline.
Patent EA-015499-B1 (EA)
Title: Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1
Inventor: WINNEROSKI LARRY LEONARD JR
IPC: A61K31/4015
Filed: 2007-04-25
Abstract: The present invention discloses novel compounds of Formula (I) having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11β-HSD type 1 activity.
Patent EA-015546-B1 (EA)
Title: Method for the power supply of an electronic component in a laminated glazing
Inventor: DEMEYERE MICHAEL
IPC: B32B17/10
Filed: 2008-03-12
Abstract: According to the invention, in order to ensure the power supply of an electronic component (8) of a laminated glazing including two superimposed glass sheets (2, 10) separated by a thermoplastic spacer (12), the electronic component (8) being provided between the two glass sheets, the electronic component (8) is connected to an AC source (11) by an electrically conducting circuit (6a, 6b) provided between the two glass sheets.
Patent EA-017992-B1 (EA)
Title: Sawing wire spool with two concentric drums as core
Inventor: GU JIANMING JACK
IPC: B21C47/28
Filed: 2008-12-19
Abstract: A spool (20) made of thick metal sheet for a fine metal wire comprises a core (22), and two flanges (24), coupled to the core (12). The core (22) comprises two concentric drums, an inner drum (26) with inner diameter d, and an outer drum (28) with outer diameter D. The spool changes the load distribution of side pressure on the flanges and further improves the structural rigidity of the spool to against deformation.
Patent EA-018848-B1 (EA)
Title: Immunologically active substance, process for preparing same, bioprobe based thereon, method for diagnostics of health state using bioprobe, pharmaceutical composition and method of treatment using pharmaceutical composition
Inventor: SHANIN VADIM YULIEVICH
IPC: A61P35/00
Filed: 2010-10-20
Abstract: The claimed group of inventions relates to bioengineering and can be used in different medicine branches for diagnostics of an individual's tissue state, treatment of said tissue diseases characterised by an uncontrolled tissue cell growth, requiring stop grow thereof by local lysis inside the organism provided obligatory control by treating with the same substance which can be a base for laboratory testing and pharmaceutical composition. The claimed technical solutions are based on the production of a novel class of substances having immune activity which are obtained from the tissue of an internal, transitory or transplanted organ, a neoplasm (tumor) in the organism of an individual, have specific activity in relation to antibodies/autoantibodies and are characterized by the presence of properties which make it possible to identify, using a laboratory procedure, the condition of the tissue of the internal organs in an individual under examination by means of identifying an antigen-antibody or autoantigen-autoantibody reaction occurring between the substance and a biological liquid taken from the individual under examination and which have partial organ and species synergy, which makes it possible to induce a response of the immune system of an organism of an individual on parenteral administration which results in local lysis of the tissue having organ and species affinity to the administered substance.
Patent EA-019498-B1 (EA)
Title: Analogues of neuropeptide y having at least one synthetic amino acid substitution
Inventor: DONG ZHENG XIN
IPC: A61K38/00
Filed: 2010-02-19
Abstract: The present invention relates to novel analogues of neuropeptide Y, pharmaceutical compositions containing the same, pharmaceutical formulations containing the same, and method of treating diseases or conditions mediated by neuropeptide Y-receptor binding. More particularly, the present invention relates to novel analogues of neuropeptide Y having at least one unnatural amino acid substitution, such as 4Hyp at position 34, that selectively bind to the neuropeptide Y1 receptor subtype compared to the neuropeptide Y2 receptor subtype.
Patent EA-025671-B1 (EA)
Title: Conveying apparatus and support device
Inventor: REIST WALTER
IPC: B65G15/60
Filed: 2010-05-07
Abstract: The invention relates to a moving conveying means (2) which extends in a planar manner, such as a conveyor belt or a mat top conveyor, for conveying piece goods (10) or bulk goods and which lies in a conveying apparatus. A group of rolling elements (5) comprising a plurality of rollers (3) is arranged between the conveying means (2) and a support element (7). The conveying means (2) moves relative to the rolling elements (5), wherein the rollers (3) roll on the conveying means (2) and on the support element (7), and the rollers are interconnected at a distance from each other by means of a flexible connecting element (4).
Patent EA-027621-B1 (EA)
Title: Length-adjustable exterior mirror arrangement
Inventor: LANG WERNER
IPC: B60R1/078
Filed: 2011-10-19
Abstract: Disclosed is an exterior mirror arrangement for motor vehicles, which has a holder (4) mounted on the vehicle; a housing (6) which is fastened thereto; and a holding member (8) for a vehicle exterior mirror, which is displaceably received in the housing (6). The housing (6) has a first housing portion (10) which is formed in one piece from plastic and which can alone guide the holding member (8), wherein a first fixing portion (72) of the first housing portion (10) mounted on the vehicle comprises a metal insert (82) molded into the first housing portion (10) to fix the first fixing portion (72) to the holder (4).
Patent EA-023401-B1 (EA)
Title: Fatty amides and their derivatives from natural oil metathesis
Inventor: ALLEN DAVE R
IPC: C09D7/63
Filed: 2011-10-25
Abstract: Fatty amide compositions and their derivatives are disclosed. The fatty amides comprise a reaction product of a metathesis-derived C-Cmonounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with a primary or secondary amine. Derivatives made by reducing, quaternizing, sulfonating, alkoxylating, sulfating, and sulfitating the fatty amide are also included. The amine reactant can be diethylenetriamine or (2-aminoethyl)ethanolamine, which provide imidazoline amides or esters, respectively. In one aspect, the ester derivative of the C-Cmonounsaturated acid or octadecene-1,18-dioic acid is a lower alkyl ester. In other aspects, the ester derivative is a modified triglyceride made by self-metathesis of a natural oil or an unsaturated triglyceride made by cross-metathesis of a natural oil with an olefin. The compositions are valuable for cleaners, fabric treatment, hair conditioning, personal care, antimicrobial compositions, agricultural uses, and oil field applications.
Patent EA-029232-B1 (EA)
Title: Composite pipe
Inventor: JONES MARTIN PETER WILLIAM
IPC: F16L11/08
Filed: 2011-12-05
Abstract: A pipe (200) comprises a pipe wall (202) formed of a composite material of a matrix and a plurality of reinforcing fibres embedded within the matrix. At least one longitudinal portion (204) of the pipe wall (202) comprises or defines a local variation in construction to provide a variation in a property of the pipe (200).
Patent EA-022437-B1 (EA)
Title: Pyridinyl- and pyrazinyl-methyloxy-aryl derivatives useful as inhibitors of spleen tyrosine kinase (syk)
Inventor: ATKINSON FRANCIS LOUIS
IPC: C07D403/12
Filed: 2012-03-08
Abstract: A compound of formula (I) or a salt thereof; which is an inhibitor of spleen tyrosine kinase (SYK) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory diseases and/or allergic conditions, in cancer therapy, specifically heme malignancies, and autoimmune conditions.
Patent EA-026289-B1 (EA)
Title: Biologically active food supplement in the form of colloid
Inventor: PROKOPIEVA LARISA ALEXANDROVNA
IPC: A23L29/25
Filed: 2013-12-19
Abstract: The invention is related to biologically active food supplements. A biologically active food supplement is made in the form of a colloid comprising: a) at least one biologically active ingredient; b) a liquid carrier including a structuring agent; c) acidity regulators; d) preservatives; e) flavours. As a biologically active ingredient, the food supplement may contain, in combination or separately, powder and/or dry extract of a medicinal plant or a mixture thereof, a macro- or microelement or a mixture thereof, and a vitamin or a mixture of vitamins. The liquid carrier including a structuring agent is made of substances of natural origin dispersed in glycerol, such substances including xanthan gum, guar gum, acacia gum, tragacanth gum, carob bean gum, konjac glucomannan. The biologically active food supplement features high bioavailability, good organoleptic properties, stability in storage. The biologically active food supplement is suitable for direct oral administering without dilution with water or other liquids and can be produced on an industrial scale at low cost without a need for any complicated devices and production stages.
Patent EA-033626-B1 (EA)
Title: AMINO-SUBSTITUTED IMIDAZO[1,2-a]PYRIDINECARBOXAMIDES, METHOD FOR PRODUCTION THEREOF, USE THEREOF AND MEDICAMENT COMPRISING SAME
Inventor: VAKALOPOULOS ALEXANDROS
IPC: A61K31/437
Filed: 2013-11-04
Abstract: The invention concerns amino substituted imidazo[1,2-a]pyridino-3-carboxamides defined in Claim 1. Another object of the present invention are methods for the production of the compounds according to the invention. Furthermore, the objects of the present invention are the use of the compounds according to the invention for producing a medicament for the treatment and/or prevention of heart failure, angina pectoris, hypertension, pulmonary hypertension, ischaemias, blood vessel diseases, renal insufficiency, thromboembolic diseases and arteriosclerosis, as well as a medicament comprising the compound according to the invention for the treatment and/or prevention of the above mentioned diseases.
Patent EA-027912-B1 (EA)
Title: Starch-based aqueous adhesive compositions and uses thereof
Inventor: BUWALDA PIETER LYKLE
IPC: C12P19/18
Filed: 2014-06-12
Abstract: The present invention relates to starch-based aqueous adhesive compositions and uses thereof. Provided is an aqueous adhesive composition comprising highly branched starch (HBS) obtained by treatment of starch or starch derivatives with a glycogen branching enzyme, and further comprising a carboxymethyl (CM) polysaccharide derivative, such as a carboxymethyl ether of starch, cellulose or a combination thereof. Also provided is a method for adhering a first substrate to a second substrate, comprising applying to at least said first or said second substrate said starch-based adhesive, and a glued or glueable product obtainable thereby.
Patent EA-032664-B1 (EA)
Title: Method for connecting a medical instrument to a position-detecting system
Inventor: KRUEGER TIMO
Filed: 2014-07-14
Abstract: The invention is related to a method for calibration of a localizing element disposed on a medical instrument by the working point of said medical instrument. For this purpose, a search sector is set in respect of the localizing element, a reference point is brought to the work point of the medical instrument tip, simultaneously the position and orientation of the localizing element are determined by a position-detecting system, and the localizing element is calibrated by the work point of the medical instrument when the work point of the instrument tip reaches the reference point. As a starting condition for calibration of the localizing element by the instrument tip, a check is performed whether the data on the reference point position are within the set search sector.
Patent EA-036156-B1 (EA)
Title: Heterodimeric antibodies that bind cd3 and tumor antigens
Inventor: MOORE GREGORY
IPC: C07K16/30
Filed: 2016-04-28
Abstract: The present invention is directed to novel heterodimeric antibodies.
Patent ES-2207991-B1 (ES)
Title: Sistema antiretroceso para vehiculos.
Inventor: CASARES CASADO VICENTE
IPC: B60T7/12
Filed: 2000-03-17
Granted: 2005-08-16
Abstract: Este sistema está destinado para ayudar a la conducción y contribuir a la seguridad, en todo tipo de vehículos. Impide, automáticamente, que el vehículo pueda retroceder de manera involuntaria cuando es detenido subiendo una pendiente, sin que el conductor tenga que accionar el freno ni realizar ninguna otra actuación, permitiéndole reanudar la marcha sin ninguna oposición. La activación del sistema es voluntaria por medio de un simple interruptor. Básicamente está compuesto por un "Detector del Sentido del Movimiento" (hacia adelante, o hacia atrás y de parada del vehículo), detectores de la situación de los frenos y de la marcha atrás y una "Unidad Electrónica de Control" que procesa las señales que recibe de estos elementos, controlando, a su vez, un sistema de freno de acción instantánea, un piloto y avisador acústico en el panel de instrumentos y la luz de marcha atrás.
Patent ES-2217892-B1 (ES)
Title: Sistema de fabricacion de placas para usos varios y placas resultantes.
Inventor: JIMENEZ FUENTES SANTOS
IPC: B44C5/04
Filed: 2000-06-07
Granted: 2006-02-01
Abstract: Sistema de fabricación de placas para usos varios y placas resultantes, del tipo de las empleadas para arte funerario, revestimientos en construcción tanto de exteriores como de interiores, mobiliario, etc., caracterizado porque sobre una placa a base de alabastrina, marmolina o similar, queda pintado cualquier motivo ornamental por medio de un film a modo de calcomanía o similar.
Patent ES-2192119-B1 (ES)
Title: Embrague de friccion.
Inventor: KIMMIG KARL-LUDWIG
IPC: F16D13/75
Filed: 1998-12-02
Granted: 2005-02-01
Abstract: Embrague de fricción para su empleo en una línea de transmisión, con un plano de apriete fijo al giro con respecto a una carcasa, pero desplazable axialmente con limitación, estando previsto entre la carcasa y el plato de apriete al menos un resorte de disco que impulsa al plato de apriete en dirección axial apartándole de la carcasa, presentando además el embrague de fricción un dispositivo de reajuste que garantiza un estado de sobretensión constante, al menos aproximadamente del resorte de disco durante la vida del embrague de fricción montado en la línea de transmisión, caracterizado porque el embrague de fricción presenta medios de levantamiento elásticos que tanto desplazan al plato de apriete axialmente con respecto a la carcasa, correspondiente al recorrido de desembrague del plato de apriete, al desembragarse el embrague de fricción, como también presentan un transcurso de fuerza progresivo al menos en este recorrido de desembrague.
Patent ES-2184603-B1 (ES)
Inventor: UGALDE BLANCO EMILIO
IPC: E05B47/06
Filed: 2001-03-20
Granted: 2004-10-01
Abstract: An internal lock (E) for safes and similar applications, with an outer console (A) that includes software with the instructions required by the user, which is connected by that passes through the wall of the safe to the lock. The latter includes a printed circuit linked to the one in the console and is operated by a power supply (D) connected to the mains. A simple mechanism composed of a latch (5), a motor (7), gears and a trigger are responsible for the operation of the latch, in accordance with the orders received.
Patent ES-2264287-B1 (ES)
Title: Pieza de embudo resistente a desgaste para testeros de cajones de persianas enrollables y el correspondiente metodo para producirla.
Inventor: ESTEVAN BELTRAN RAFAEL
IPC: E06B9/58
Filed: 2002-09-20
Granted: 2007-10-01
Abstract: Pieza de embudo resistente a desgaste para testeros de cajones de persianas enrollables y el correspondiente método para producirla. Para equipar cajones de persianas enrollables de lamas, se proporciona una pieza de embudo con un cuerpo de base (10), paredes de guía (2, 3) opuestas y generalmente paralelas entre sí con respectivas zonas de embocadura (20, 30) y de salida (21, 31), cuyas paredes de guía (2, 3) determinan un canal de deslizamiento (4) con una pared de fondo (40), teniendo además un apéndice de inserción en forma de mango (5) generalmente recto y alineado con el canal de deslizamiento (4) para acoplamiento a los respectivos carriles de guía de la puerta o ventana. Según la invención, la pared de fondo (40) tiene un recubrimiento (6) resistente a desgaste frente al esfuerzo de rozamiento y cizalla que en dicha zona ejercen los extremos de las lamas de persiana durante su desplazamiento, por ejemplo, en forma de placa metálica, con un cuerpo central (70) que forma la zona resistente a desgaste y aletas laterales (71) con taladros (72, 73) a través de los que puede penetrar el material plástico en que se moldea dicha pieza de embudo. La placa (7) se mantiene colocada en el molde (M) antes del proceso de inyección (I) mediante taladros de posicionamiento (74).
Patent ES-2211327-B1 (ES)
Title: Precursores opticamente puros de paroxetina.
Inventor: BAYOD JASANADA MIGUEL
IPC: C12P41/00
Filed: 2002-12-18
Granted: 2005-10-16
Abstract: Precursores ópticamente puros de paroxetina. Se describe la síntesis de precursores ópticamente enriquecidos de trans-4-(4- fluorofenil)-3-hidroximetilpiperidinas mediante un proceso biocatalítico basado en la resolución enzimática de derivados racémicos de fórmula general III (donde R3 es preferentemente fenilo o bencilo) empleando anhídridos cíclicos o el ácido de Meldrum (2,2-dimetil-1,3-dioxano-4,6-diona) como agentes acilantes del hidroxilo. Dependiendo de la enzima y las condiciones de reacción seleccionadas, es posible obtener cualquiera de los dos enantiómeros con alta pureza enantiomérica. Estos compuestos son importantes intermedios en la síntesis del antidepresivo paroxetina.
Patent ES-2223272-B1 (ES)
Title: Procedimiento para la transformacion de tableros de okumen en piezas diferenciadas con las capas interiores a la vista y de aplicacion diversa.
Inventor: ALVAREZ GONZALEZ JESUS
IPC: B32B21/13
Filed: 2003-06-17
Granted: 2007-07-01
Abstract: Procedimiento para la transformación de tableros de okumen en piezas diferenciadas con las capas interiores a la vista y de aplicación diversa que consiste en la utilización de un tablero (1) formado por un cuerpo (2) de aglomerado, revestido por láminas de okumen hasta obtener una superficie (4) ondulada sobre piezas (3), o bien las piezas (3) de superficie recta, consiguiéndose la obtención de piezas de balaustre (5) mediante el corte del tablero (1) en tiras de grosor adecuado utilizándose máquinas fijas o portátiles, en las cuales los discos de corte o labrado, están dotados de una inclinación apropiada.
Patent ES-2268918-B1 (ES)
Title: Tumbona dotada de un sistema nebulizador de agua.
Inventor: ASIAIN INSA OSCAR
IPC: A47C7/74
Filed: 2003-08-21
Granted: 2008-02-16
Abstract: Tumbona dotada de un sistema nebulizador de agua, siendo del tipo de tumbonas utilizadas para tomar el sol en diferentes lugares, de forma que la tumbona (1) incorpora un circuito hidráulico (2) presentando un conector (3) de conexión de una conducción desde una toma de agua, una llave (4) de paso del agua y una serie de microdifusores (5), quedando el circuito hidráulico (2) queda montado en la parte inferior de la tumbona (1) con la llave (4) de paso accesible al usuario y con los microdifusores (5) del agua distribuidos en la superficie de la tumbona (1).
Patent ES-2237317-B1 (ES)
Title: Sistema multiparametrico para el diagnostico de rechazo post-trasplante e inflamacion basado en la temperatura y la impedancia electrica tisular.
Inventor: CINCA CUSCOLLA JUAN
IPC: A61B5/042
Filed: 2003-11-07
Granted: 2006-11-01
Abstract: Sistema multiparamétrico para el diagnóstico de rechazo post- trasplante e inflamación basado en la temperatura y la impedancia eléctrica tisular. La presente invención se refiere a un método y a un equipo para diagnosticar y/o monitorizar episodios de rechazo de un órgano o tejido sólido tras un trasplante y/o la inflamación visceral de etiología infecciosa, autoinmune o tóxica. Un caso concreto es el del trasplante de corazón, pero puede ser aplicado en trasplantes de otros órganos y también en la implantación de tejidos biológicos. El método se basa en la medida de la temperatura local del órgano o tejido transplantado o inflamado y de su impedancia eléctrica a una o más frecuencias. La medida puede realizarse mediante catéteres o sistemas de medida implantados. En el caso de trasplante de corazón también puede realizarse mediante una sonda esofágica. En el caso de órganos o tejidos con una posición cercana a la superficie corporal las medidas pueden realizarse de forma no invasiva.
Patent ES-2267364-B1 (ES)
Title: Circuito y tecnica de modulacion para reducir armonicos particulares del espectro de la perturbacion en convertidores de potencia conmutados.
Inventor: GAGO BARRIO JAVIER
IPC: H03L7/00
Filed: 2004-11-23
Granted: 2008-03-01
Abstract: Circuito y técnica de modulación para reducir armónicos particulares del espectro de la perturbación en convertidores de potencia conmutados. Circuito integrado en el sistema de conmutación de los convertidores de potencia conmutados que consigue reducir selectivamente los armónicos de la frecuencia de conmutación que provocan interferencias conducidas en las líneas de alimentación del convertidor. El funcionamiento del circuito reductor se basa en la modulación en frecuencia de la señal de conmutación.