baber/WOPTO huggingface dataset:
Patent AT-E189960-T1 (AT)
Inventor: HELLMAN LARS T
IPC: A61K39/00
Filed: 1992-09-25
Granted: 2000-03-15
Abstract: PCT No. PCT/SE92/00673 Sec. 371 Date Mar. 23, 1994 Sec. 102(e) Date Mar. 23, 1994 PCT Filed Sep. 25, 1992 PCT Pub. No. WO93/05810 PCT Pub. Date Apr. 1, 1993The invention relates to a vaccine, preferably for human use, against IgE-mediated allergic reactions. The vaccine contains a protein having the entire amino acid sequence of the constant CH2-CH3 domains of the epsilon chain of the IgE molecule or a structurally stable unit of said amino acid sequence, the protein optionally being coupled to one or more heterologous carrier proteins, and optionally containing an adjuvant. The vaccine is injected, with or without adjuvant, to raise the concentration of endogenous anti-IgE antibodies in the plasma of allergy subjects. In practice, the vaccine can be used against all types of IgE-mediated allergies since the antibodies are not dependent of the antigen specificity of the IgE molecule but will reduce the total IgE pool of the subject. Therefore, the vaccine is aimed at being used for treatment of subjects having different types of IgE-mediated allergies. The increased concentrations of anti-IgE antibodies reduces the free pool of antigen-specific IgE, which thereby strongly reduces the risk for an allergen-mediated release of the physiologically highly active substances which are stored or produced in connection with granula release from mast cells and basophilic leucocytes.
Patent AT-E164282-T1 (AT)
Inventor: DELAKOWITZ BERND
IPC: H01R11/01
Filed: 1993-12-04
Granted: 1998-04-15
Abstract: The innovation relates to a distribution arrangement, especially for the main distribution frame of telephone and data lines, comprising a distribution rack, a distribution frame, pivotable frames, to terminate the system side and the subscriber side. To achieve the object of the innovation, i.e. to develop a distribution arrangement of the generic type in which the jumpering facilities and the adaptation to computerised switching system facilities are improved and in which the organisation of a main distribution frame is thereby optimised, the subscriber side and the system side are disposed adjacent to one another on a profile frame in modular form and are set up vertically on top of one another in relation to rack rows located next to one another. <IMAGE>
Patent AT-E169007-T1 (AT)
Inventor: FINCH HARRY
IPC: C07D243/12
Filed: 1993-01-15
Granted: 1998-08-15
Abstract: Compounds of general formula (I) <CHEM>  wherein R<1> represents a phenyl, C3-7cycloalkyl, C7-11 bridgedcycloalkyl or C1-6alkyl group which alkyl group may be substituted by a hydroxy, phenyl, C1-6alkoxycarbonyl, C3-7cycloalkyl, or C7-11 bridgedcycloalkyl group; R<2> represents a substituted or unsubtituted phenyl group (wherein the substitutents may be 1 or 2 of halo, C1-4alkyl, nitro, cyano, trifluoromethyl, trifluoromethoxy, C1-4alkylthio or (CH2)n R<4> wherein R<4> is hydroxy, C1-4alkoxy, CO2R<5> or NR<6>R<7>.  R<3> is phenyl optionally substituted by one or two halogen atoms;  R<5> represents hydrogen or a C1-4alkyl group;  R<6> and R<7> independently represent hydrogen or a C1-4alkyl group.  R<8> represents hydrogen or a halogen atom; m is zero, 1 or 2; n is zero or 1; are antagonists of gastrin and CCK-B receptors
Patent AT-E145894-T1 (AT)
Inventor: NAKAI HISAO
IPC: C07D295/18
Filed: 1993-09-17
Granted: 1996-12-15
Abstract: Amidinophenol derivatives of the formula (I): <CHEM> wherein R<1> and R<2> are (i) H, (ii) C1-4 alkyl, (iii) C1-4 alkoxy, (iv) C2-5 acyl, (v) halogen, (vi) NO2, (vii) benzoyl, (viii) COOR<4>(in which R<4> is C1-3 alkyl); A is bond, C1-4 alkylene, -C(R<5>)=C(R<6>)- (in which R<5> and R<6> are H or C1-4 alkyl); R<3> is (i) CON(R<7>)(R<8>), (ii) CON(R<9>)-CH(R<7>)(R<8>) or (iii) <CHEM> (in which R<7> and R<8> are (1) H, (2) phenyl, (3) C7-10 phenylalkyl, (4) pheny or C7-10 phenylalkyl substituted by 1or 2 C1-4 alkyl, halogen or R<1><1>-COOR<1><2> (in which R<1><1> is bond, C1-8 alkylene, C2-8 alkenylene, C2-8 alkynylene; R<1><2> is H, C1-4 alkyl, C7-10 phenylalkyl, phenyl, allyl, propargyl), (5) C1-10 alkyl, (6) C2-10 alkenyl having 1 to 3 double bonds, (7) C2-10 alkynyl having 1 or 2 triple bonds, (8) R<11a>-COXR<1><2>(in which R<11a> is (a) bond, (b) C1-8 alkylene, (c) C2-8 alkylene in which 1 or 2 carbon atoms in the main chain are replaced by sulfur, or sulfur and phenylene, (d) C2-8 alkenylene, (e) C4-8 alkenylene in which 1 or 2 carbon atoms in the main chain are replaced by sulfur, or sulfur and phenylene, (f) C2-8 alkynylene, (g)C4-8 alkynylene in which 1 or 2 carbon atoms in the main chain are replaced by sulfur, or sulfur and phenylene; X is -O- or -NH-), (9) C1-4 alkyl substituted by a 7-14 membered, bi- or tri-cyclic hetero ring containing one N atom, (10) C3-7 cycloalkyl); R<9> is (1) H, (2) C1-8 alkyl, (3) C7-10 phenylalkyl, (4) C2-10 alkenyl having 1 to 3 double bonds, (5) C2-10 alkynyl having 1 or 2 triple bonds, (6) R<1><1>-COOR<1><2>, (7) C3-7 cycloalkyl;  @  @ is 4-7 membered, mono-cyclic hetero ring containing 1 or 2 N atom; R<1><0> is H, C7-10 phenylalkyl or COOR<1><3>(in which R<1><3> is H, C1-4 alkyl or C7-10 phenylalkyl)); with the proviso that (i) both R<7> and R<8> do not represent hydrogen at the same time, and (ii) when at least one group in R<7>, R<8> and R<9> represents the group containing t-butyl ester, the other groups do not represent the group containing carboxy; or an acid addition salt thereof, have inhibitory activities on PLA2 and on various proteases such as trypsin, plasmin, thrombin, kallikrein, especially trypsin, and are useful for the prevention and/or the treatment of various inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis, severity in pancreatitis and multiple organ failure.
Patent AT-E169122-T1 (AT)
Inventor: MOONEN CHRIT T W
IPC: G01R33/20
Filed: 1993-02-26
Granted: 1998-08-15
Abstract: A method for enhancing the sensitivity of gradient-recalled echo imaging for T2* effects in dynamic magnetic resonance imaging which involves the step of delaying gradient-recalled echoes so that the gradient-recalled echoes are subjected to magnetic susceptibility effects for an extended period of time. The gradient-recalled echoes are delayed beyond a subsequent radio frequency pulse by applying an additional gradient which dephases any gradient-recalled echo of spins that are excited in the radio frequency repetition time period in which said gradient-recalled echoes are produced.
Patent AT-E140880-T1 (AT)
Inventor: WILDING PETER
IPC: A01K67/02
Filed: 1993-04-29
Granted: 1996-08-15
Abstract: Disclosed are devices and methods for the clinical analysis of a sperm sample. The devices comprise a solid substrate, typically on the order of a few millimeters thick and approximately 0.2 to 2.0 centimeters square, microfabricated to define a sample inlet port (16A) and a mesoscale flow channel (20, 40) extending from the inlet port (16A). In one embodiment, a sperm sample is applied to the inlet port (16A), and the competitive migration of the sperm sample through the mesoscale flow channel (20, 40) is detected to serve as an indicator of sperm motility. In another embodiment, the substrate of the device is microfabricated with a sperm inlet port (16A), an egg nesting chamber (16B), and an elongate mesoscale flow channel (20, 40) communicating between the egg nesting chamber (16B) and the inlet port (16A). In this embodiment, a sperm sample is applied to the inlet port, and the sperm in the sample is permitted to competitively migrate from the inlet port (16A) through the channel (20, 40) to the egg nesting chamber (16B), where in vitro fertilization occurs. The devices of the invention may be used in a wide range of applications in the analysis of a sperm sample, including the analysis of sperm morphology or motility, to assess sperm binding properties, and for in vitro fertilization.
Patent AT-E156379-T1 (AT)
Inventor: JUSTICE DONALD R
IPC: B01D17/12
Filed: 1993-05-13
Granted: 1997-08-15
Abstract: A series of horizontally extending drainage pipes forming a grid system are located at or below the level of a plume of liquid contamination. The drainage recovery pipes skim off the surface of the water table, along with the plume of contamination. This minimizes the time required for removal of water that needs to be pumped from the ground and cleaned. Once the contaminant is pumped from the ground, it is delivered to a conventional treatment system where it is cleaned and then the cleaned water is returned back to the ground water table. This cleaned water is reintroduced over the grid system and is drawn through the soil to flush out any remaining contaminants in the soil. Once the treated water reaches the water table, the liquid contaminants are usually less dense than water and rise towards the surface of the water table. The contaminants are then removed by the grid system for treatment.
Patent AT-E142980-T1 (AT)
Inventor: OERN KAUNO
IPC: B65G65/48
Filed: 1993-02-10
Granted: 1996-10-15
Abstract: The invention relates to a device for controlled feeding of particulate, flowing substance. The device consists of an outflow part (1) of a vessel containing the substance to be fed and a proportioning disk (4) rotated underneath its mouth opening at an operational clearance, a flow guiding structure (12) formed at the mouth opening of the outflow part (1) and opening spirally in the rotation direction of the proportioning disk (4) and forming an out flow opening (8), and a doctor blade (5) mounted away from the outflow opening (8) in the rotation direction of the disk for the purpose of removing the material from the disk. The diameter of the mouth opening of the outflow part (1) is no more than approximately half of the diameter of the proportioning disk (4), and the doctor blade (5) is placed at a distance of at least approximately half a rotation away from the outflow opening (8) in the rotation direction of the proportioning disk (4).
Patent AT-E147105-T1 (AT)
Inventor: RIZZO ANGELO MICHELE
IPC: C12P21/02
Filed: 1993-07-20
Granted: 1997-01-15
Abstract: A method for increasing both total antibiotic yield the selective production of factor A of the GE 2270 antibiotics consisting in the addition of vitamin B12 or its analogs having vitamin B12-like activity to the fermentation media of (Planobispora rosea) ATCC 53773 or any antibiotic GE 2270 producing mutant or variant thereof.
Patent AT-E283698-T1 (AT)
Inventor: SUFFIS ROBERT
IPC: A61K31/74
Filed: 1993-09-22
Granted: 2004-12-15
Abstract: Described is a fragrancing composition having fragrancing components that are not activated until, e.g., application to the skin of a human. The composition is alkaline or (if anhydrous) capable of producing an alkaline pH when in contact with water, prior to application, and includes (1) a vehicle such that when the composition is in contact with water, prior to application, the composition is at an alkaline pH; and (2) at least one potential fragrance that is at least one compound having little or no odor in the alkaline composition but which, e.g., is hydrolyzed in a lower pH environment to produce compounds having a relatively strong aroma. Upon application of the alkaline composition to the skin surface, the strong buffering capacity of the skin (the surface of which has a normal pH of 5.5-7.0) neutralizes alkalinity of the composition (lowers pH) so as to restore normal skin surface pH; the potential fragrance is then hydrolyzed at the lower pH to release the compound having relatively strong aroma. The potential fragrance can be incorporated as a component of a transparent (clear) deodorant stick composition for application to human axillary regions, the fragrance being released after application to the body.
Patent AT-E330606-T1 (AT)
Inventor: LIPTON STUART A
IPC: A61K9/70
Filed: 1993-09-22
Granted: 2006-07-15
Abstract: Disclosed is a method for decreasing NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a nitroso-compound that generates nitric-oxide or related redox species, in a concentration effective to effect neuroprotection. Also disclosed is a method for decreasing NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a nitroso-compound that generates nitric oxide (or a related redox species such as NO31 or NO+equivalent), or a physiologically concentration effective to cause such neuroprotection.
Patent AT-E131427-T1 (AT)
Inventor: FLOESER BERNHARD
IPC: B23H9/00
Filed: 1994-01-24
Granted: 1995-12-15
Abstract: In order to be able to assemble construction units which radially enclose the rotor of a turbine, these construction units must consist of two halves. It is conventional practice to largely complete, for example, an intermediate base first of all as a closed ring and then to separate it into a top and bottom part before assembly. The parting line resulting during the sawing must be compensated for upon assembly by expensive measures. According to the invention, an improvement is obtained owing to the fact that the parting line 1 is produced by electrical discharge wire cutting, and the cutting line, running in its basic direction along a division plane 4, of an erosion wire 5 specifically moves away from the division plane 4 at least once and then specifically runs towards it again. <IMAGE>
Patent AT-E171535-T1 (AT)
Inventor: KURR KLAUS-JUERGEN DIPL-ING
IPC: F16K7/12
Filed: 1994-04-26
Granted: 1998-10-15
Abstract: The damper has a damping volume (17) on the rear of a plate (9) which moves in a space and which separates the duct instantaneous pressure from the mean pressure of the hydraulic system. The rear of the plate is backed by a weak spring (15,17) to hold the plate in a mean reference position. The damping volume is linked to the hydraulic duct by a flow restriction (23) and the spring can be backed by a gas spring. Loading of the plate controls the damping frequencies while an active damping can be provided by a servo drive acting on a movable wall section. <IMAGE>
Patent AT-E167989-T1 (AT)
Inventor: LIN BANG H
IPC: A47G19/22
Filed: 1994-04-29
Granted: 1998-07-15
Abstract: A beverage container with a rotatable cover and an automatically extendable drinking straw. The container comprises an open ended body closed by a removable cap, straw means inserted through a conduit on the cap, a cover member rotatably fitted on the cap for rotation movement relative to the cap between a first position allowing the straw to extend through a slot of the cover member and a second position folding the straw means and closing the slot. A groove formed on the cap engages a raised spot formed on the inner edge of the cover member for indicating when the cover member is rotated to either the first or second position. The straw means comprises a first straw made of elastomeric material and a second straw made of rigid material and sized so that the first straw is held between the conduit and the second straw in a coaxial relation without the use of fastening elements. <IMAGE>
Patent AT-E176594-T1 (AT)
Inventor: STEINEL JR HEINRICH WOLFGANG
IPC: A01M1/20
Filed: 1994-08-03
Granted: 1999-02-15
Abstract: A heat exchanger is in contact with a heater and is located at the point at which the substance is to be evaporated. The device has a wall power point connection (5) which has primary and secondary rotational couplings inside the housing (1a, 1b). Each rotational coupling has contacts which can be connected to corresp. contacts of the other coupling. The contacts are displaced through 90 degrees in the rotational coupling sections so that electrical connections can be made between the power point contacts (6) and the heater.
Patent AT-E192430-T1 (AT)
Inventor: ALIG LEO
IPC: C07D401/12
Filed: 1994-11-26
Granted: 2000-05-15
Abstract: Acetic acid derivatives of the formula <IMAGE> in which L, M, Q and T have the meaning stated in the description, can be used for the treatment or prophylaxis of diseases caused by the binding of adhesive proteins to blood platelets, and by aggregation of blood platelets and cell-cell adhesion. They are prepared by eliminating protective groups in corresponding protected compounds or by converting the cyano group into the amidino group in corresponding nitriles.
Patent AT-E181040-T1 (AT)
Inventor: JANSEN ROLF-MICHAEL DR
IPC: C01B33/154
Filed: 1994-12-07
Granted: 1999-06-15
Abstract: The invention relates to a process for preparing modified SiO2 gels, known as "xerogels", and also to the xerogels thus prepared themselves and their use. The xerogels are prepared by acidifying an aqueous waterglass solution, polymerising the silicic acid thus formed by addition of a base to give an SiO2 gel, substantially washing the water from the gel using an organic solvent, reacting the gel with a silylation agent and then drying it at from -30 to 200 DEG C and at from 0.001 to 20 bar.
Patent AT-E204042-T1 (AT)
Inventor: KANGAS WILLIAM W
IPC: E02D29/16
Filed: 1994-01-24
Granted: 2001-08-15
Abstract: A shaped, water-expandable water-sealing article (12) used for sealing an area between a first section (32) of at least partially cured concrete and a second, adjacent section (34) of substantially uncured concrete to form a plurality of water-sealed concrete sections. The clay water sealing article (12) is in the shape of quadrilateral, preferably a trapezoid, and is disposed to bridge an area between the two sections of concrete. Upon hydration of the clay contained within the shaped water sealing article, expansion of the clay creates expansion forces extending from a corner of the article that is surrounded by the uncured concrete, wherein the corner has an included angle greater than 90 DEG , preferably at least 100 DEG . The expansion force developed by the expansion of the shaped water sealing article are absorbed by a substantially increased area of the uncured concrete as compared to expansion forces resulting from a clay-based water seal having a 90 DEG included angle at the corner (s) surrounded by the uncured concrete. <IMAGE>
Patent AT-E149962-T1 (AT)
Inventor: EGGER WALTER C
IPC: B65G47/31
Filed: 1994-08-23
Granted: 1997-03-15
Abstract: A conveying apparatus (1) for the conveyance of bottles (10) has an entry-side connecting conveyor (3), a main conveyor (2) and an exit-side connecting conveyor (7). In order to guarantee a reliable transfer of the bottles (10), even of those with stability insufficient for belt conveyance, from the entry-side connecting conveyor (3) to the main conveyor (2) and from the main conveyor (2) to the exit-side conveyor (7), there are provided in the transfer regions auxiliary devices (6, 8, 13, 16, 18) which specifically define the spatial orientation of the bottles (10) and thereby ensure a reliable transfer of the bottles (10) from one conveyor to the other (3, 2; 2, 7). Provision is made, furthermore, for the auxiliary devices (6, 8, 13, 16, 18) to be displaceable between an operative position and a position of rest. As a result, both PET bottles with a stability insufficient for belt conveyance and glass bottles can be transported on such a conveying apparatus (1). <IMAGE>
Patent AT-E181364-T1 (AT)
Inventor: CHANG YIN-FU
IPC: A01H1/00
Filed: 1993-12-13
Granted: 1999-07-15
Abstract: The present invention is drawn to the production of fertile transformed wheat plants. The method involved subjecting wheat tissues to high velocity microprojectile bombardment, selecting for transformed cells, and regenerating stably transformed fertile plants from the transformed cells.
Patent AT-E194292-T1 (AT)
Inventor: BERG ARNE
IPC: A61K9/107
Filed: 1994-03-16
Granted: 2000-07-15
Abstract: Oil-in-water emulsions in which the oil phase comprises condensed or dissolved oil-soluble gas/fluid or gas precursor are useful as ultrasound contrast agents. Such products contain insignificant amounts of free gas bubbles or microbubbles in their stored form and exhibit good storage stability, but may be designed to promote rapid microbubble generation immediately before or upon administration.
Patent AT-E149975-T1 (AT)
Inventor: LIAGRE FRANCOIS
IPC: B09B3/00
Filed: 1994-04-15
Granted: 1997-03-15
Abstract: PCT No. PCT/FR94/00426 Sec. 371 Date Feb. 12, 1996 Sec. 102(e) Date Feb. 12, 1996 PCT Filed Apr. 15, 1994 PCT Pub. No. WO94/24060 PCT Pub. Date Oct. 27, 1994The invention relates to apparatus for processing waste, in particular hospital waste, the apparatus including a gasification chamber (1) into which the waste is inserted to be subjected to degassing and to combustion, a post-combustion chamber (2) for the gases coming from the gasification chamber, and a melting chamber (3) in which the slag coming from the gasification chamber (1) is exposed to high temperature for vitrification purposes.
Patent AT-E166877-T1 (AT)
Inventor: SCHNUR RODNEY C
IPC: C07D487/04
Filed: 1994-03-14
Granted: 1998-06-15
Abstract: This invention relates to compounds of the formuladefined below. Such compounds are useful as oncogene inhibitors and antitumor agents.
Patent AT-E149555-T1 (AT)
Inventor: CHANG YEONG-HO
IPC: C09D5/03
Filed: 1994-06-13
Granted: 1997-03-15
Abstract: Provided are thermosetting powder coating compositions comprised of an aliphatic carboxyl resin, a  beta -hydroxylalkyl amide crosslinker, and a catalyst comprised of a C1-C18 carboxylate salt of a metal selected from the group consisting of zinc, aluminum, and titanium, or an oxide of aluminum or zinc. Preferably, the aliphatic resin is comprised of residues of 1,4-cyclohexanedicarboxylic acid (CHDA) and 2,2,4,4-tetramethyl-1,3-cyclobutanediol or comprised of 1,4-CHDA and hydrogenated bisphenol A. We have found that certain compounds, particularly certain zinc salts, catalyze the crosslinking reaction and significantly reduce gel time.
Patent AT-E257515-T1 (AT)
Inventor: ZIMMERMANN THOMAS
IPC: C12N15/09
Filed: 1994-10-07
Granted: 2004-01-15
Abstract: PCT No. PCT/EP94/03317 Sec. 371 Date Jul. 2, 1996 Sec. 102(e) Date Jul. 2, 1996 PCT Filed Oct. 7, 1994 PCT Pub. No. WO95/10613 PCT Pub. Date Apr. 20, 1995An isolated DNA fragment including the genes bcoC, bcoA/B, bcoD coding for the enzymes for L-carnitine biosynthesis in  gamma -butyrobetaine/crotonobetaine metabolism and, additionally, including the gene bcoT coding for a potential transport protein in  gamma -butyrobetaine/crotonobetaine metabolism. Also, any vector which includes an isolated DNA fragment including the genes bcoC, bcoA/B, bcoD coding for the enzymes for L-carnitine biosynthesis in  gamma -butyrobetaine/crotonobetaine metabolism and, additionally, including the gene bcoT coding for a potential transport protein in  gamma -butyrobetaine/crotonobetaine metabolism. Also, biotechnological process for the production of L-carnitine characterized in that crotonobetaine and/or  gamma -butyrobetaine is fermented in the presence of a suitable carbon and nitrogen source using a microorgansim and L-carnitine is isolated.
Patent AT-E166497-T1 (AT)
Inventor: NATHER THOMAS
IPC: F28F3/02
Filed: 1995-01-19
Granted: 1998-06-15
Abstract: The electrical arcing absorber has a box shaped housing with an inlet (2) and an outlet (3) for the hot gas flow generated. Located between inlet and outlet are two heat exchanger groups (4,5) that are set at 90 degrees to each other. Each heat exchanger consists of plates set in a 'V' shaped patterns with flow passages (7) in between. Perforated plates (8,10) provided turbulence smoothing at exit from each stage.
Patent AT-E194268-T1 (AT)
Inventor: HURST SIEGFRIED
IPC: A47B13/02
Filed: 1995-04-05
Granted: 2000-07-15
Abstract: The support pad incorporates an annular groove (7) with cylindrical outer wall, in which the support tube (1) fits and a conical inner wall (6) on which a split conical tube section (2) is mounted. The tube section (2) is made from a hard material such as steel while the tube is made from a softer material e.g. aluminium alloy. A disc (5) is mounted on top of the conical tube (2). A number of screws (4), which pass through holes in the bottom of the pad, are used to pull the disc (5) down to force the conical tube into the ID of the tube. <IMAGE>