baber/WOPTO huggingface dataset:
Patent MA-27615-A1 (MA)
Title: Composes de pyrazolo[3,4-b]pyridine et leur utilisation en tant qu'inhibiteurs de phosphodiesterase
Inventor: DAVID GEORGE ALLEN
IPC: A61P25/00
Filed: 2005-07-20
Abstract: L'invention concerne un composé représenté par la formule (I) ou un de ses sels dans laquelle: R1 représente alkyle C1-4, fluoroalkyle C1-3 ou -(CH2)2OH; R2 représente un atome d'hydrogène (H), méthyle ou fluoroalkyle C1; R3a représente un atome d'hydrogène (H) ou alkyle C1-3; R3 représente alkyle C3-6 ramifié éventuellement substitué, cycloalkyle C3-8 éventuellement substitué, cycloalkényle C5-7 monoinsaturé éventuellement substitué, phényle éventuellement substitué ou un groupe hétérocyclique éventuellement substitué, représenté par la formule secondaire (aa), (bb) ou (cc) dans lesquelles n1 et n2 sont indépendamment 1 ou 2; et Y représente O, S, SO2, ou NR4; et dans laquelle Het est représenté par les formules secondaires (i), (ii), (iii), (iv) ou (v). Ces composés sont des inhibiteurs de phosphodiestérase (PDE), en particulier, des inhibiteurs de PDE4. Elle concerne également la mise en application d'un composé représenté par la formule (I) ou d'un de ses sels acceptables sur le plan pharmaceutique afin de préparer un médicament servant à traiter et/ou à prévenir une maladie inflammatoire et/ou allergique chez un mammifère, tel que l'humain, par exemple, la broncho-pneumopathie chronique obstructive, l'asthme ou la rhinite allergique.
Patent MA-28143-A1 (MA)
Title: Preparation de transfusion contenant un acide (2r)-2-propyloctanoique comme ingredient actif
Inventor: SUDOH MASAO
IPC: A61K9/00
Filed: 2006-05-02
Abstract: La présente invention porte sur une préparation pour infusion qui est utile pour les maladies neurodégénérative, qui comprend l'acide (2R)-2-propyloctanoïque ou son sel et un ion de métal basique qui est pourvu d'un sel de métal ou un hydroxyde de métal de l'acide faible, de préférence de 1 à 5 équivalents environ de l'ion de métal basique sur la base de 1 équivalent de l'acide (2R)-2-propyloctanoïque ou son sel, et comprend facultativement en plus des composants pour infusion. La préparation pour infusion de la présente invention a un pH approprié pour l'administration intraveineuse, et elle est utile pour l'administration intraveineuse puisqu'elle n'exige pas une opération préparatoire telle que la dissolution, la dilution ou les opérations similaires au moment de l'emploi.
Patent MA-20150213-A1 (MA)
Title: Structure autoportante pour l'installation de cartouches de filtration cylindriques
Inventor: BERRADA MEHDI
IPC: C02F1/44
Filed: 2013-11-04
Abstract: Ii s’agit d'une ceinture de sécurité gonflable remplie d’air comprimé munie d'une électrovanne et de capteurs. En cas de détection de noyade, |’éiectrovanne se déclenche et ia ceinture se transforme en bouée en quelques secondes. En méme temps un signal est activé dans ia zone pour alerter les maitres nageurs ou les responsables adultes.
Patent UY-23944-A1 (UY)
Title: Rollo de bolsas de plastico para utilizar con el dispensador de bolsas
IPC: B65D85/671
Filed: 1995-04-05
Abstract: Se describe un rollo de bolsas que comprende un dispositivo separador con una estructura, un medio para sostener un eje en el que se monta el rollo con relación a la estructura, una lengüeta con ambos lados en la porción delantera del dispensador y un dedo que se extiendo hacia arriba, adyacente y más allá de la lengüeta, y espaciado de la lengüeta de forma que se defina un hueco entre ambos, estando dicho hueco posicionado de forma que reciba una porción de una bolsa sucesiva adyacente a la bolsa guía que ha de ser separada y que retenga dicha porción a medida que la bolsa guía es separada del rollo de bolsas de plástico, estando dicho hueco adaptado de forma de permitir que dicha porción se aparte del hueco solamente en la misma dirección en que recibió dicha porción de la bolsa; un eje; un rollo de bolsas de plástico abobinado en el eje que incluye líneas de separación entre las bolsas adyacentes y una ranura en cada línea de separación, la lengüeta se extiende hacia arriba para enganchar la ranura en una de las líneas de separación que se encuentran entre las bolsas durante la separación y el ancho del rollo con relación a la lengüeta es tal que cuando la bolsa guía se ha separado del rollo, la siguiente está a ambos lados de la lengüeta y sus porciones respectivas se extienden más allá de la lengüeta en una posición que permite que un usuario la tome. Se ilustra en la figura 1.
Patent UY-28138-A1 (UY)
Title: Intermedio de formulación aceptablemente no higroscópico que comprende un fármaco higroscópico
Inventor: CZYZEWSKI ANN M
IPC: A61K31/155
Filed: 2003-12-19
Abstract: Se proporciona una composición particulada sólida que comprende un fármaco higroscópico y/o delicuescente y al menos un polímero no higroscópico. El fármaco y el por lo menos un el polímero están en asociación intima y la composición es aceptablemente no higroscópica.
Patent UY-28596-A1 (UY)
Title: Nuevo anhidrato cristalino con accion anticolinergica
Inventor: SIEGER DR PETER
IPC: C07D451/10
Filed: 2004-11-03
Abstract: La invención se refiere a un nuevo anhidrato cristalino de bromuro de tiotropio, a procedimientos para su obtención, y a su empleo para preparar un medicamento para tratar enfermedades de las vías respiratorias, en especial para tratar la enfermedad pulmonar obstructiva crónica (siglas inglesas COPD= chronic obstructive pulmonary disease) y el asma.
Patent UY-30015-A1 (UY)
Title: Combinación de antagonista de actividad biológica de angiopoyetina-2 y antagonista de actividad biológica de vegf-a y/o kdr y/o flt1, composiciones farmacéuticas y aplicaciones
Inventor: BLAKEY DAVID CHARLES
IPC: A61P9/10
Filed: 2006-12-15
Abstract: La invención se refiere a agentes que poseen actividad antiangiogénica y son por lo tanto útiles en métodos de tratamiento de estados de enfermedad vinculados a la angiogénesis en el cuerpo de un animal o ser humano. Más específicamente la invención se refiere a una combinación de un antagonista de la actividad biológica de Angiopoyetuna-2 y un antagonista de la actividad biológica de VEGF-A y/o Kdr y/o Ft11, y a los usos de dichos antagonistas.
Patent UY-30489-A1 (UY)
Title: Ingrediente lacteo rico en componentes de la membrana de globulos de la leche, procedimiento de obtencion y aplicaciones del mismo.
Inventor: DALEMANS DANIEL
IPC: A23L23/00
Filed: 2007-07-16
Abstract: Ingrediente lácteo enriquecido en lípidos polares, en particular en fosfolípidos y en esfingolípidos, en el que el porcentaje de fosfolípidos es superior al 10% en peso, con respecto al peso de materia seca del ingrediente, su procedimiento de obtencion a partir de crema de leche pasteurizada y su aplicacion en productos alimentarios y/o farmacéuticos.
Patent UY-30680-A1 (UY)
Title: Combinaciones pesticidas
Inventor: OOSTENDORP MICHAEL
IPC: A01N37/22
Filed: 2007-10-31
Abstract: Un método para controlar o prevenir el dano ocasionado por patogenos o plagas en un material de propagacion de plantas, partes de una planta y/u organos de la planta que se han de desarrollar en un momento posterior, que comprende aplicar a la planta, su parte o sus alrededores, una combinacion pesticida que comprende, al menos tres componentes ingredientes activos optativamente junto con uno o más auxiliares de la formulacion habituales, donde el componente (I) al menos un funguicida -azol, el componente (II) al menos un funguicida de fenilamina y el componente (III) es azoxistrobina, en cualquier orden o simultáneamente.
Patent UY-30807-A1 (UY)
Title: Inhibidores de serina palmitoiltransferasa
Inventor: HUIS CHAD ALAN VAN
IPC: A61K31/439
Filed: 2007-12-19
Abstract: La invencion proporciona compuestos de formula (I) utiles en la inhibicion o modulacion de serina palmitoiltransferasa y su uso en procedimientos de tratamiento o mejora de diabetes de tipo 2, diabetes de tipo 1, resistencia a insulina, los efectos de la obesidad, sindrome metabolico, intolerancia a la glucosa, enfermedad de Cushing, enfermedad cardiovascular, afecciones protromboticas, infarto de miocardio, hipertension, insuficiencia cardiaca congestiva, cardiomiopatía, aterosclerosis, dislipidemia, sepsis, dano hepático, trastornos degenerativos retinales, caquexia, enfisema, infecciones por hepatisis C, infecciones por VIH y trastornos inflamatorios, y utiles en procedimientos para elevar los niveles plasmáticos de LAD en un mamífero. Los compuestos de esta invencion pueden utilizarse también para prevenir el dano o pérdida de células beta islotes pancreáticos (tal como en el caso de apoptosis de células beta pancreáticas, incluyendo aquellas relacionadas con diabetes mellitus insulinodependiente).
Patent UY-31006-A1 (UY)
Title: Plantas de brassica resistentes a herbicidas y métodos de uso
Inventor: DARYL MALES
IPC: A01H1/02
Filed: 2008-04-04
Abstract: La invencion provee plantas transgénicas y no transgénicas con mejores niveles de tolerancia a herbicidas inhibidores de AHAS. La invencion también provee ácidos nucleicos que codifican mutantes de la subunidad grande de acetohidroxiácido sintasa (AHAS), vectores de expresion, plantas que comprenden los polinucleotidos que codifican las subunidades de AHASL que contienen mutaciones simples, dobles o mayores, plantas que comprenden uno, dos o más polipéptidos mutantes simples de subunidad AHASL, a métodos para prepararlos y usarlos, y a métodos de control de malezas.
Patent ES-180681-A1 (ES)
Title: Mejoras en disposiciones de circuito
Filed: 1947-11-27
Abstract: Mejoras en disposiciones de circuito para mejorar la linealidad de la razón de cambio de un campo magnético producido por una bobina de trabajo, como una bobina de desviación electromagnética de una válvula de rayos catódicos, caracterizado por una bobina captadora o de toma de campo, acoplada inductivamente a la bobina de trabajo,estando conectado un terminal de la bobina de toma, aun punto de potencial susbstancialmente constante y el otro terminal a un electrodo de gobierno del circuito de excitación de la bobina de trabajo.
Patent ES-183817-A1 (ES)
Title: UN PROCEDIMIENTO PARA LA MANUFACTURA DE TABLERO DURO DE PARED, DE SERRiN Y OTROS DESPERDICIOS CELULoSICOS.
IPC: D21J1/08
Filed: 1948-05-22
Abstract: Procedimiento para la manufactura de tablero duro de pared, de serrín y otros desperdicios celulósicos o de un producto fibroso duro, denso y resistente al agua, reuniendo una sustancia lignosa en un producto de una nueva forma y densidad, en presencia de un activador químico, consistiendo dicho procedimiento en añadir el agente activador a un material de fibra corta, en su condición seca, granular, seguido esto de la fase de someter la mezcla de dicho agente activador y del material de fibra a calor y presión, estando elegido el agente activador de los hidroxi-derivados de hidro carburos aromáticos teniendo una estructura en que el grupo hidroxi está directamente fijado al anillo.
Patent ES-197093-A1 (ES)
Title: Un aparato pulverizador perfeccionado
Filed: 1951-03-17
Abstract: Un aparato pulverizador perfeccionado que esencialmente se caracteriza por haberse previsto en el cuerpo (1) del aparato pulverizador una conducción (5) para la entrada del aire a presión necesario para la pulverización cual conducción establece comunicación constante con un vaciado axial (8) practicado en la boquilla (4) que se fija en el interior del citado cuerpo del aparato pulverizador vaciado axial (8) que no alcanza el fondo o parte posterior de la mencionada boquilla.
Patent ES-254257-A1 (ES)
Title: Moulding compositions comprising epoxidized novolak, novolak and amine
IPC: C08L63/04
Filed: 1959-12-17
Abstract: A hardenable moulding composition comprises: (a) a polyglycidyl ether of a phenolformaldehyde novolak condensation product obtained under acid conditions (b) a phenolformaldehyde novolak condensation product obtained by condensation under acid conditions and (c) a base with a nitrogenous basic group as hardening accelerator. Specified bases are triethanolamine, triethylene tetramine, dimethyl amino-propylamine, tris-dimethylaminophenol, dimethylbenzylamine, phenyl hydrazine, pyridine and hexamethylene tetramine. Fillers, e.g. asbestos, chalk powder, mica, kaolin, quartz powder, metal powder, metal oxides or rock meals, dyestuffs, plasticizers and lubricants may be present in the compositions. Example (1) describes the preparation of a novolak by reacting phenol with formaldehyde in the presence of hydrochloric acid, the preparation of a polyglycidyl ether by reacting the novolak with epichlorohydin and ethylene glycol monomethyl ether, the admixture of the novolak and polyglycidyl ether with hexamethylene tetramine, glycerol monostearate and bolus alba, the mixture being moulded and cured. In Examples (2) to (5) the polyglycidyl ether of Example (1) is mixed with glycerol monostearate, a reaction product of the novolak of Example (1) with (2) dimethylaminopropylamine (3) dicyandiamide (4) tris-[dimethylamino] phenol and (5) triethanolamine and (2) kaolin (3) and (4) kaolin and nigrosine and (5) steatate, the mixtures being moulded and cured.
Patent ES-273488-A1 (ES)
Title: Process and furnace for melting and working products such as glass
IPC: C03B5/185
Filed: 1962-01-08
Abstract: <PICT:0987106/C1/1> A glass melting furnace comprises a preheating shaft 2 disposed above a melting chamber 4 in which burners 14 are disposed below the surface 21 of the melt, electrodes or resistors 19 at the foot of chamber 4, and a connection 17 to a refining tank 7 having an extraction orifice 8. The rate of flow over this orifice controls the level of the melt surface and hence the depth of immersion of the burners. The latter may be disposed in pairs in two opposite walls, singly in all four walls, singly in two opposite walls with a pair in a third wall, inclined horizontally or vertically or disposed at different levels, Figs. 2-7 (not shown). In another embodiment, Fig. 8 (not shown), a vertically adjustable dam controls the entrance to the refining chamber to vary the aforementioned melt surface level. This dam may be of low density material sliding in side grooves under control of upper locating blocks, Figs. 9 and 10 (not shown).
Patent ES-302534-A1 (ES)
Title: Production of seamed metal tubes
IPC: B21C37/08
Filed: 1964-07-29
Abstract: Apparatus for the continuous production of seamed metal tubes comprises means feeding a metal band to a cutting location, where it is cut into a plurality of strips positioning means locating the strips in spaced relationship and forming means associated with each strip. Prior to passing to the forming means, alternate strips are preferably turned over so that the burrs formed by cutting all face the same way. The forming means shown forms three tubes simultaneously by conventional methods, but the forming rollers G2 for the middle strip are offset longitudinally from the pairs of rollers G1, G3 to reduce the width of the apparatus. Guides 9a, welding rollers S1, S2, 53 and, weld trimmers 11, 12, 13 are similarly offset. High-frequency current may be supplied by contact or inductively. The formed tubes are passed through a cooling unit to a number of straightening units and finally to a cutting unit.
Patent ES-306123-A1 (ES)
Title: Tubular heat exchangers
IPC: F28F1/42
Filed: 1964-11-17
Abstract: A heat exchanger element comprises a central tube 1 which is connected to an outer tube 2 by a first series of radial fins 3a, 3b, and has a second series of radial fins 4 which extend from the outer tube part way towards the inner tube. As shown, other fins 6 may extend inwardly from the inner tube in alignment with the fins 3a, 3b.
Patent ES-308791-A1 (ES)
Title: Transmission and recording of signals in echo-sounding apparatus
IPC: G01S7/60
Filed: 1965-01-30
Abstract: In an echo-recorder for use with hydrographic surveying, oceanographic, navigational, fish-detection, or flaw-detection echo-sounding apparatus in which a recording stylus is moved across the recording medium by an endless belt, the transmission of an acoustic pulse is synchronized with the movement of the stylus by means of two rotary switches which are driven from the belt and whose relative speed of rotation is such that both switches operate simultaneously once in each complete circuit of the belt to trigger the transmitter. In the embodiment of Fig. 3 a belt 23, e.g. a toothed belt or a chain, runs on wheels 22 and 24 and carries the stylus 17 of the recorder (Fig. 1, not shown) which may be of the electrochemical type. The two rotary switches comprise contacts 27, 29 on the wheels 22, 24, which co-act with stationary contacts 28, 30 respectively. The dimensions of the wheels and belt are such that for one circuit of the belt wheel 22 makes 3 complete revolutions and wheel 24 makes 5 complete revolutions, both switches operating simultaneously when the stylus 17 is in the position shown. In order to record from different ranges, the instant of transmission may be advanced or retarded (in relation to the 'position of stylus 17) by moving contact 28 to one of four alternative positions 28a-28d equally spaced round the circumference of wheel 22 (Figs. 2a-2e, not shown), or by selecting a stationary contact at one of these positions by means of a switch 36. For an incremental range adjustment, e.g. to compensate for displacement of the transmitter from a datum level, the angular positions of both stationary contacts 28, 30 may be adjusted continuously between fixed limits (Figs. 4, 5, 6, not shown), the two angular adjustments being ganged together, e.g. by a toothed belt (Fig. 7, not shown), such that the contacts 28, 30 are rotated through angles having the same ratio as the angular speeds of the respective rotary contacts 27, 29. In an alternative embodiment (Figs. 8, 9, not shown) the two rotary switches comprise drums 60, 67 having respective conducting strips 61, 68 for bridging pairs of contact arms, one drum 60 being driven directly from the toothed belt and the other drum 67 being driven through gearing from the first drum 60. Instead of mechanical contacts, the rotary switches may employ cams, photoelectric or electromagnetic induction switching systems.
Patent ES-337334-A1 (ES)
Title: Foamed Polyurethane Compositions
IPC: C08J9/35
Filed: 1967-02-28
Abstract: A laminate may be produced by depositing on a continuously moving conveyer the surface of which comprises paper, board or other facing material, a mixture of an inorganic particulate material and a partially expanded polyurethane foam material and providing an upper surface for the mixture which is the surface of a second conveyer moving at substantially the same speed as the first conveyer, which upper surface is also of paper, board or other facing material. In a specific example, granules of foamed glass or sintered shale are fed at a controlled and uniform rate from shoot 12 on to a moving web of paper 13 by means of vibrating hopper 14. A froth of polyurethane foam precursor is then deposited on to the paper prior to the granules and/or cutting across the fall path of the granules from a hose 15 which leads from a mixer 16. The web of paper is then carried by the driven belt conveyer 21, above which is a second driven continuous belt conveyer 24 on to which is supplied a second web of paper from supply roll 26. The second conveyer is located generally at a point where. the foam aggregate mixture has almost but not completely completed its expansion. The product emerging from between the two conveyers at 27 consists of a continuous laminate comprising the composition of polyurethane foam and particulate material with facings of paper on either side thereof. This continuous laminate may then be cut by the guillotine device 22.
Patent ES-347307-A1 (ES)
Title: Improvements in or relating to thermo-electric ignition safety devices
IPC: F27D21/00
Filed: 1967-11-17
Abstract: A safety control device for gaseous fuel comprises within a housing 10, 11 an ignition safety valve 13, pilot burner valve 14, and main burner valve 15, each valve having a valve closure member 16, 46, 34, respectively, loaded by springs 24, 48, 36 towards valve seats 17, 47, 35, and said device also including a control knob 32 connected with a control rod 26 having rotatable therewith a sleeve 30, the knob 32 having "off", "ignition" and "open" positions corresponding to different stages of an ignition cycle, and there being within the housing a solenoid 18 provided with an electromagnet 21 adapted to be energized by a thermo-current produced by a thermo-element heated in the pilot flame. The device operates as follows assuming that it is initially in the "off" condition illustrated in Fig. 1. Gas enters the housing via inlet 101 and is retained in space 51 by valve 13 until knob 32 is pushed towards the housing and is rotated by means of a lug 42 thereon engaging a cam surface 40 on a sleeve 39 fixed to cover-plate 12. Since sleeve 30 is, by means of rod 26, attached to knob 32, it moves in and relates therewith, the inward movement of the sleeves rotating a bell-crank 27 so that an arm 29 thereof forces valve closure member 16 off its seat, and rotation of the sleeve causing a cam-surface 50 thereon to force a rod 49 upwardly thereby displacing valve closure member 46 from its seat. Gas passes via valve 13, space 52 and valve 14 to the pilot burner where it is ignited, the flame heating the thermo-element and producing a thermo-current which energizes magnet 22. Attached to valve stem 19 is an armature plate 20 which is attracted to and retained by magnet 22 after it has been lifted theretowards by crank-arm 29. The knob is now pulled from cover-plate 12 and rotated in the opposite direction, this movement causing rod 26 to pull valve closure member 34 away from its seat and allow gas to pass to the main burner to be ignited by the pilot burner. If the knob is now returned to its initial "off" position the supply of gas to the pilot and main burners is cut off since closure members 34 and 46 enter their seats. The closure member of valve 13 will however remain open during the time the thermo-element remains hot and during this time an arm 55 of the bell-crank enters a slot in sleeve 30 preventing a new ignition cycle from being started since it will not be possible to turn knob 32. Only when the thermo-element has cooled and there is no thermo-current will the armature plate be released by the magnet 22, thus causing closure member to reseat itself and rotate the bell-crank by means of arm 29. This rotation will lift bell-crank arm 55 from the slot in sleeve 30 and allow a new ignition cycle to proceed.
Patent ES-347496-A1 (ES)
Title: Liquid fuel supply systems for internal combustion engines
IPC: F02M59/46
Filed: 1967-11-10
Abstract: A device 11 for producing pilot injection similar to that of Fig. 2 of Specification 1, 060,181, is modified in that the restriction 22 through which the pilot fuel is forced by a piston 23 is a variable restriction formed by a spring-loaded piston 33 co-operating with orifice 22. The pilot fuel flows through orifice 36 in piston 33, the pressure drop across which orifices varies the position of the piston in relation to orifice 22. Orifice 22 discharges into a groove 18 through which the main fuel injection also flows when piston 23 opens the main orifice 20. The pistons 23, 33, slide in a bore 19 in a valve member 14 which lifts off its seat on the end of member 11 at the end of injection to permit fuel to return from the passage 13 leading to the injector to the pump 9. In Fig. 2 the valve 14 is replaced by a non-return valve 40 and a non-return valve 41 closes the end of piston 23 until the latter opens the main orifice 20. A restriction 44 in the passage 21 controls the rate of discharge of liquid from the space between the pistons 23, 33.