baber/WOPTO huggingface dataset:
Patent CA-2497121-A1 (CA)
Title: Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
Inventor: DUGGER HARRY A III
IPC: A61K38/00
Filed: 2003-08-27
Abstract: Buccal aerosol sprays or capsules using polar and non-polar solvent have now been developed which provide biologically active compounds for rapid absorption through oral mucosa, resulting in fast onset of effect. The buccal compositions of the invention comprise formulation I: aqueous polar solvent, action compound, and optional flavoring agent; formulation II: aqueous polar solvent, active compound, optionally flavoring agent, and propellant;  formulation III: non-polar solvent, active compound, and optional flavoring agent; and formulation IV: non-polar solvent, active compound, and optional flavoring agent; and propellant.
Patent CA-2497335-A1 (CA)
Inventor: HECKER MARKUS
IPC: C12N15/87
Filed: 2003-09-02
Abstract: The invention relates to a pharmaceutical formulation for the internalizatio n of nucleic acids into eucaryotic cells, characterized in that the formulatio n has a pH value of 6.0 - pH 7,4, and/or an anion concentration of 5 - 100 mmol/l and/or a concentration of 10 - 500 mol/l of nonsteroidal antiphlogist ic agents.
Patent CA-2497422-A1 (CA)
Title: Slider window assembly and method of fabrication thereof
Inventor: CUSSON PHILIPPE
IPC: B60J10/74
Filed: 2005-02-18
Abstract: A slider window assembly, comprising a one-piece slider frame and seal assembly and a window panel mounted therein; the one-piece slider frame and seal assembly comprising a multi-material core and sheath parts, allowing an increased fabrication precision and therefore an improved water-tightness.
Patent CA-2497883-A1 (CA)
Title: Method for distinguishing ulcerative colitis from crohn's disease by detecting the presence of fecal anti-neutrophil cytoplasmic antibodies (anca)
Inventor: BOONE JAMES HUNTER
IPC: G01N33/68
Filed: 2003-09-05
Abstract: A method and apparatus for the differentiation of ulcerative colitis from Crohn's disease and other gastrointestinal illnesses using the presence of anti-neutrophil cytoplasmic antibodies (ANCA) as a marker of ulcerative colitis is described. The apparatus consists of either a qualitative enzyme-linked immunoassay or other immunoassay that utilizes antibodies specific to human immunoglobulins for the measurement of total endogenous ANCA in a human sample. The method and apparatus can be used by healthcare providers to distinguish ulcerative colitis from Crohn's disease and other gastrointestinal.
Patent CA-2498300-A1 (CA)
Title: Tuned vented hull
Inventor: PALLADINO MICHAEL
IPC: B06B3/00
Filed: 2005-02-18
Abstract: A harmonic system designed to minimize the drag in the semi-planning range of a vessel. The vibratory generator is tuned with respect to the fundamental frequency of the vessel at the onset of planning and to the spectra of the vortex sheet. As the vessel speed increases to planning speeds, a sympathetic vibration occurs that assist in overcoming the trans-planning region of the vessel.
Patent CA-2498667-A1 (CA)
Inventor: NELSON DWAYNE R
IPC: G06F12/02
Filed: 2003-09-11
Abstract: L'invention concerne un procédé et un appareil permettant de stocker dynamiquement des données critiques de machine de jeu par affectation et désaffectation d'espace mémoire dans ladite machine de jeu. Dans un ou plusieurs modes de réalisation(s), un nouveau jeu est téléchargé dans une machine de jeu ou supprimé de celle-ci de sorte que toutes les données critiques existant dans la mémoire RAM non volatile restent intactes. Dans un mode de réalisation, l'invention concerne un procédé et un appareil permettant d'affecter ou de désaffecter dynamiquement un espace mémoire permettant d'effectuer un stockage permanent ou temporaire dans mémoire RAM non volatile. Un procédé et un appareil permettent de surveiller l'espace mémoire disponible et de redimensionner la mémoire dans une mémoire RAM non volatile. D ans un autre mode de réalisation, un procédé permet de vérifier l'intégrité de la mémoire RAM non volatile et de déterminer une erreur de donnée critique. Dans un ou plusieurs modes de réalisation(s), des procédés permettent de compresser et de décaler des contenus de mémoire RAM non volatile afin de consolider l'espace mémoire disponible ou d'empêcher l'accès non autorisé à la mémoire RAM non volatile.
Patent CA-2500509-A1 (CA)
Title: Rear wiper bracket assembly
Inventor: WARD MICHAEL E
IPC: B60S1/02
Filed: 2005-03-11
Abstract: A windshield wiper bracket assembly for mounting on a motor vehicle panel includes a bracket adapted to mount on one side of the panel and a threaded fastener extending through the panel, with an arm for engaging an opposite side of the panel. The threaded fastener is received in a hole of the bracket for securing the bracket while sandwiching a portion of the panel between the bracket and the arm.
Patent CA-2502186-A1 (CA)
Title: Fungicides
Inventor: CROWLEY PATRICK JELF
IPC: C07C235/20
Filed: 2003-11-10
Abstract: Fungicidal compounds of the general formula (1): wherein X, Y and Z are independently H, halogen, Cl-4 alkyl, halo(C1-4)alkyl, C2-4 alkenyl, halo(C2-4)alkenyl, C24 alkynyl, halo(C2-4)alkynyl, C1_4 alkoxy, halo(C1-4)alkoxy, -S(O)n(C1-4)alkyl where n is 0, 1 or 2 and the alkyl group is optionally substituted with fluoro, -OS02(C1-4)alkyl where the alkyl group is optionally substituted with fluoro, cyano, nitro, C,1-4 alkoxycarbonyl, -CONR'R", -COR', -NR'COR" or -NR'COOR"' where R' and R" are independently H or C1-4 alkyl and R"' is Cl-4 alkyl, provided that at least one of X and Z is other than H; R1 is Cl-4alkyl, C2-4 alkenyl or C2-4 alkynyl in which the alkyl, alkenyl and alkynyl groups are optionally substituted on their terminal carbon atom with one, two or three halogen atoms, with a cyano group, with a C1-4 alkylcarbonyl group, with a C1-4 alkoxycarbonyl group or with a hydroxy group; R2 is H, C1-4 alkyl, C1-4 alkoxymethyl or benzyloxymethyl in which the phenyl ring of the benzyl moiety is optionally substituted with CI-4alkoxy; R3 and R4 are independently H, C1-3 alkyl, C2-3 alkenyl or C2-3 alkynyl provided that both are not H and that when both are other than H their combined total of carbon atoms does not exceed 4, or R3 and R4 join with the carbon atom to which they are attached to form a 3 or 4 membered carbocyclic ring optionally containing one 0, S or N atom and optionally substituted with halo or C1-4alkyl; and R5 is unsubstituted C3-4 alkyl, unsubstituted C3-6 cycloalkyl or Cl-4 alkyl or C3-6 cycloalkyl in which the alkyl and cycloalkyl groups are substituted with halo, hydroxy, C1-6 alkoxy, cyano, C1-4 alkylcarbonyloxy, aminocarbonyloxy, mono- or di(C1_4)alkylaminocarbonyloxy, -S(O)"(C1-6)alkyl where n is 0, 1 or 2, triazolyl, tri(C1-4)alkylsilyloxy, optionally substituted phenoxy, optionally substituted thienyloxy, optionally substituted benzyloxy or optionally substituted thienyl-methoxy, in which the optionally substituted phenyl and thienyl rings of phenoxy, thienyloxy, benzyloxy and thienylmethoxy are optionally substituted with one, two or three substituents selected from halo, hydroxy, mercapto, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4alkoxy, C2-4 alkenyloxy, C2-4 alkynyloxy, halo(C1-4)~alkyl, halo(C1-4)alkoxy, C1-4 alkylthio; halo(C1-4)alkylthio, hydroxy(C1-4)alkyl, C1-4 alkoxy(C1-4)alkyl, C3-6 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, phenoxy, benzyloxy, benzoyloxy, cyano, isocyano, thiocyanato, isothiocyanato, nitro, -NR-R', -NHCORm, -NHCONRmR", -CONRmR", -S02Rm, -OS02Rm, -CORM, -CR'=NR" or -N=CRmR", in which R"' and R" are independently hydrogen, CI-4 alkyl, halo(C1-4)alkyl, C1-4 alkoxy, halo(C1-4)alkoxy, C1-4alkylthio, C3-6 cycloalkyl, C3-6 cycloalkyl(C 1-4)alkyl, phenyl or benzyl, the phenyl and benzyl groups being optionally substituted with halogen, C1-4alkyl or C1-4 alkoxy.
Patent CA-2505393-A1 (CA)
Inventor: VOLLRATH FRIEDRICH WILHELM LUD
IPC: B29C48/30
Filed: 2003-11-14
Abstract: The application relates to an extrusion apparatus, which comprises at least one first reservoir (1) connected at a first end to a first opening of a plurality of regulatory modules (4). The regulatory modules or spinnerets contain tubular passages (17) through which dope material (25) is extrudable . The extrusion apparatus (4) has at least 1,000 of the tubular passages (17) per square metre cross~section.
Patent CA-2507633-A1 (CA)
Title: Content management system
Inventor: FORRESTER AUDREY
IPC: G06F3/0484
Filed: 2003-11-26
Abstract: A computer system may include a contact center interface and a presentation interface. The contact center interface may provide a user with access to a contact center application, which manages and renders information pertaining to customer~centric problems. The presentation interface may provide the use r with access to a content management system (or knowledge management system) for information regarding goods, services and associated support. The comput er system may display two simultaneously visible content regions, where the operations in one content region are independent of operations in the second content region. One of the content regions may reflect the contact center interface while the other content region may reflect the information application interface. The two content regions may be dynamic such that whil e the regions are independent, the content displayed within one content region is context-appropriate to the other content region. Such a system may also include a display region for an instant messaging tool. The content manageme nt system may include a database having a set of content items stored in a taxonomy, where the taxonomy has at least two primary categories. The categories may associate items that represent products, items that represent services, items that represent information for campaigns, items that represe nt information for user procedures, and/or items that represent user intentions (customer needs). Each content item in the database may be associated to one or more content~owners. A user may submit feedback for one of the content items. That feedback may be routed to the content-owner associated to the content item without requiring the user to know or to determine who the content-owner is. The content owner may be: a content author, a content manager, an advocate for the content owner, or a team of people. The feedbac k may be a comment explaining any errors in the content item, a rating of the usefulness of the content item, or a comment for content improvement.</SDOAB >
Patent CA-2510641-A1 (CA)
Inventor: SAYEEDI SHAHAB M
IPC: H04L29/08
Filed: 2005-06-23
Abstract: Various embodiments are described to address the need for more effective management of packet data loss in wireless communication systems. When a packet data destination (131) that is receiving a flow of packets for a packet data service instance indicates to the packet data source (141) of the flow that the flow should be suspended, it also indicates to the source how to process packets for the service instance while the flow transmission is suspended. For example, the packet data destination may indicate an event or condition that is triggering the flow suspension, the source can then begin buffering packets, discarding packets, starting timers, and/or taking other packet processing actions to manage packet data loss in view of the packet data destination's indication. Alternatively, the packet data destination may explicitly indicate the packet processing actions the source should take while the packet flow is suspended.
Patent CA-2511359-A1 (CA)
Title: Steroid receptor modulation of gene expression
Inventor: STRAUSS JOSEPH
IPC: C12N1/19
Filed: 2003-12-23
Abstract: The present invention provides a novel steroid inducible expression system in a non-mammalian host cell (e.g., fungal) that is independent of metabolic and development regulation. The human estrogen receptor gene expressed in Aspergillus, under a constitutive promoter, was shown to be functional. A  reporter gene containing regulatory sequences from Aspergillus, yeast and a synthetic sequence containing the estrogen receptor binding sites (EREs) was expressed in response to a hormone derivative inducer. In the absence of the inducer, the promoter is silent and depending on the type of construct and inducer concentration the expression level can e modulated from moderate to very strong.
Patent CA-2513004-A1 (CA)
Title: Aptamer therapeutics useful in ocular pharmacotherapy
Inventor: MARSH NICHOLAS
IPC: A61K47/48
Filed: 2004-01-21
Abstract: The invention provides nucleic acid therapeutic compositions capable of binding to cytokines, growth factors and cell surface proteins, individually or in combinations of two or more, and methods for delivering these nucleic acid therapeutics in the treatment of glaucoma and other proliferative diseases of the eye.
Patent CA-2514564-A1 (CA)
Inventor: BULLEIT ROBERT F
IPC: C12Q1/26
Filed: 2004-01-30
Abstract: A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention.  Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein.
Patent CA-2516091-A1 (CA)
Inventor: SEN DIPANKAR
IPC: C12Q1/68
Filed: 2003-03-11
Abstract: The electrical conductivity of DNA and other oligonucleotide constructs is dependent on its conformational state. Such a dependence may be harnessed for the electronic sensing of external analytes, for instance, adenosine. Such a DNA sensor incorporates an analyte receptor, whose altered conformation in the presence of bound analyte switches the conformation, and hence, the conductive path between two oligonucleotide stems, such as double-helical DNA. Two distinct designs for such sensors are described that permit significant electrical conduction through a first or "detector" double-helical stem only in the presence of the bound analyte. In the first design, current flows through the analyte receptor itself whereas, in the second, current flows in a path adjacent to the receptor. The former design may be especially suitable for certain categories of analytes, including heterocycle-containing compounds such as adenosine, whereas the latter design should be generally applicable to the detection of any molecular analyte, large or small. Since analyte detection in these DNA sensors is electronic, the potential exists for their application in rapid and automated chip-based detection of small molecules as well as of proteins and other macromolecules.
Patent CA-2522117-A1 (CA)
Inventor: CHEN HONG JYH
IPC: E05B45/06
Filed: 2005-10-03
Abstract: A method of operating a control panel in a security system that includes a door entry security device in a housing suitable for mounting within a recess of a doorjamb or door of a premises. The control panel is programmed to register a system arm/disarm device and a door closure device, both with the same identification number, such that the control panel recognizes that identification number to be associated with a door entry security device. In the even that the control panel receives, while in an armed state, an alarm signal from a security device in the security system and then receives a system disarm message, then the control panel determines if the system disarm message was received from a system arm/disarm device that has been registered as a door entry security device. If the control panel determines that the system disarm message was received from a system arm/disarm device that has been registered as a door entry security device, then the system disarm message is ignored; and if the control panel determines that the system disarm message was not received from a system arm/disarm device that has been registered as a door entry security device, then the system disarm message is followed.
Patent CA-2522712-A1 (CA)
Title: Nerve regenerating drug
Inventor: IKEDA SHUN-ICHI
IPC: C12N5/0797
Filed: 2004-04-16
Abstract: It is intended to provide a drug for nerve degeneration, a nerve stem cell neurogenesis promoter, a neuron obtained by culturing a nerve stem cell in the presence of the neurogenesis promoter, and a method of producing the neuron.  To achieve the above objects, a drug for nerve degeneration which contains as the active ingredient a substance inhibiting the activity of a glycogen synthase kinase-3, a nerve stem cell neurogenesis promoter containing this substance as the active ingredient, a neuron obtained by culturing a nerve stem cell in the presence of the neurogenesis promoter, and a method of producing the neuron are provided. The above-described drugs are useful as remedies for nerve diseases such as Parkinson~s disease, Alzheimer~s disease, Down~s disease, cerebrovascular disorder, cerebral stroke, spinal injury, Huntington~s chorea, multiple sclerosis, amyotrophic lateral sclerosis, epilepsy, anxiety disorder, integration dysfunction syndrome, depression and manic-depressive.
Patent CA-2522813-A1 (CA)
Title: 2-alkynyl-and 2-alkenyl-pyrazolo-¬4,3-e|-1,2,4-triazolo-¬1,5-c|-pyrimidine adenosine a2a receptor antagonists
Inventor: HAO JINSONG
IPC: A61P25/16
Filed: 2004-04-21
Abstract: Compounds having the structural formula (I) or a pharmaceutically acceptable salt thereof, wherein R is R1, R2, R3, R4 and R5 are H, alkyl or alkoxyalkyl;  R6 is H, alkyl, hydroxyalkyl or -CH2F; R7, R8 and R9 are H, alkyl, alkoxy, alkylthio, alkoxyalkyl, halo or -CF3; and Z is optionally substituted aryl, heteroaryl or heteroaryl-alkyl are disclosed. Also disclosed is the use of compounds of formula I in the treatment of central nervous system diseases, in particular Parkinson's disease, alone or in combination with other agents for treating Parkinson's disease, and pharmaceutical compositions comprising them.
Patent CA-2525766-A1 (CA)
Inventor: LEENHOUTS CORNELIS JOHANNES
IPC: C07K16/12
Filed: 2004-05-17
Abstract: The invention relates to the field of biology, more specifically to the field of immunology and microbiology. The invention further relates to the field of vaccines against microbial infections and especially bacterial vaccines, in particular to pneumococcal vaccines. More in particular, the invention relates to means and methods to identify, select and isolate a vaccine component for passive and/or active immunisation against a microorganism that can be killed by opsonophagocytic cells. The invention relates to a method to identify an opsonophagocytosis inducing antigen as a vaccine component for immunisation against a microorganism. The invention describes three pneumococcal proteins SlrA, IgA1 proteinase, and PsaA, and their use as a vaccine component with or without PpmA. The invention also discloses the use of antibodies against said proteins for passive immunization and diagnosis.
Patent CA-2529824-A1 (CA)
Inventor: KATO ATSUYA
IPC: C09D133/04
Filed: 2005-12-13
Abstract: An aqueous amino resin dispersion excelling in storage stability and mechanical stability which is formed by dispersing hydrophobic amino resin in aqueous medium, using a polyester resin having specific hydroxyl value, acid value and number-average molecular weight as a dispersion stabilizer, said polyester resin being prepared by reacting polyhydric alcohol, polycarboxylic acid and/or polycarboxylic anhydride and monoepoxide compound having a long chain hydrocarbon group thermosetting, water-based paint compositions comprising the aqueous amino resin dispersion and multi-layered coating film-forming methods using the water-based paint compositions are provided.
Patent CA-2530303-A1 (CA)
Inventor: DIETRICH ANTON
IPC: B32B17/10
Filed: 2004-06-25
Abstract: A coated article is provided so as to include an overcoat having, an outermost layer including silicon nitride which overlies an underlayer including a metal oxide (MOx) or a metal oxynitride (MOxNy), where the metal (M) is selected from the group of Cr, Nb, Hf, Ta, and/or combinations thereof. Such an overcoat provides for good mechanical and chemical protection in the context of heat treatable coated articles. Coated articles herein may be used in the context of insulating glass (IG) window units, architectural or residential monolithic window units. vehicle windows, and/or the like.
Patent CA-2532484-A1 (CA)
Title: Control arrangement for switchgear
Inventor: ZHOU YUIJIAN
IPC: H02B11/26
Filed: 2006-01-10
Abstract: A control arrangement is provided for an array of circuit interrupters that includes mounting and handling features to transport the array of circuit interrupters between various operating positions within the enclosure. In a specific arrangement, the control arrangement also provides for transporting of the array of circuit interrupters to a position to the exterior of the enclosure. In a specific arrangement, the circuit interrupters are modular and removable from the array. In a preferred arrangement, viewing facilities are provided to observe the array of circuit interrupters to verify the operating positions of the circuit interrupters, specifically, the disconnected and grounded positions. Additionally, a grounded position internal to the enclosure avoids the necessity of manually attaching grounds. In a preferred arrangement, detection of the operational states of the circuit interrupters is also provided in the various positions.
Patent CA-2534347-A1 (CA)
Inventor: WAGNER JAMES
IPC: A61F2/00
Filed: 2004-07-23
Abstract: The invention provides a surgical sling assembly for implanting in tissue to provide anatomical support in a patient. The surgical sling assembly includes a sling and a biocompatible casing enclosing at least a portion of the sling.  The biocompatible casing is absorbed by the patient's tissues after the surgical sling assembly is positioned within the patient's tissue to provide anatomical support.
Patent CA-2535496-A1 (CA)
Title: Development framework for mixing semantics-driven and state driven dialog
Inventor: LECOEUCHE RENAUD JULIEN
IPC: G06F9/44
Filed: 2006-02-07
Abstract: An application program interface embodied on one or more computer readable media is disclosed. The interface includes a first dialog container configured to facilitate development of a first type of dialog within an application. Also included is a second dialog container configured to facilitate development of a second type of dialog within the application.
Patent CA-2537325-A1 (CA)
Title: Aza-quinolinol phosphonate integrase inhibitor compounds
Inventor: KIM CHOUNG U
IPC: A61K31/53
Filed: 2004-09-17
Abstract: Aza-quinolinol phosphonate compounds and methods for inhibition of HIV-integrase are disclosed. Formula (I). Ar is aryl or heteroaryl connecting R6 to L. L is a bond or a linker connecting a ring atom of Ar to N. The ring atoms, X1-X5 may be N, substituted nitrogen, or substituted carbon, and form rings. The compounds include at least one phosphonate group covalently attached at any site.
Patent CA-2538916-A1 (CA)
Title: Pillow
Inventor: LAVIN MICHAEL P
IPC: A47G9/10
Filed: 2006-03-08
Abstract: A pillow with ellipsoidal surface configurations between each of a length and a width of a rectangularly shaped peripheral boundary. An elastic frame provides an internal cavity between sidewalk joined by protruding arcuate corners for receiving an elastically displaced overlying internal mass. This mass is bounded by elongated internal hinged segments terminating at spaced apart parting lines extending in the direction of the length and width of the rectangular pillow boundary.