baber/WOPTO huggingface dataset:
Patent CA-2893549-A1 (CA)
Inventor: SINHA INDRAJIT
IPC: C12N15/06
Filed: 2013-12-02
Abstract: The present invention provides a method to rapidly screen tumor cells for invasive and metastatic characteristics, heterogeneity and their response to therapeutic agents, and provides a multi-well microinjection system for the automated imaging and microinjection of zebrafish embryos.
Patent CA-2896379-A1 (CA)
Inventor: MCKEAN ROBERT JAMES
IPC: C12M1/12
Filed: 2013-02-07
Abstract: The invention provides a multi-well assay plate, comprising: a plate base, which defines the bottom of a plurality of sample wells; a scaffold layer disposed on the plate base, which scaffold layer provides a porous three-dimensional network of polymer nanofibres in each of said sample wells; and a plate frame, which defines the side walls of said sample wells; wherein the plate frame is bonded to the plate base through the scaffold layer. The invention further provides a process for producing the multi-well assay plate. Further provided is a scaffold which comprises a porous three dimensional network of electrospun polymer nanofibres, wherein the mean diameter of the polymer nanofibres is from 500 nm to 10 µ??. A process for producing the scaffold is also provided, as are various uses of the multi-well plate and the scaffold in drug screening, regenerative medicine and tissue engineering.
Patent CA-2898685-A1 (CA)
Title: Method of insulating a building
Inventor: BEATTIE RONALD PETER
IPC: E04B1/76
Filed: 2014-02-07
Abstract: A method of insulating a building that includes one or more existing external walls (2) and an existing roof structure (4) supported by the walls, comprises constructing a first external shell structure (24a) that covers an outer surface of at least one external wall, said shell structure being spaced from the outer surface of the wall to provide a wall void (28) between the external wall and the shell structure. A second shell structure (24b) is constructed that extends around or through the existing roof structure (4) and provides an enclosed roof void (26b) that extends around or through the roof structure. The roof void (26b) is interconnected with the wall void (26a). The wall void (26a) and the roof void (26b) are filled with an insulating material to provide an insulating layer (28) that extends substantially continuously through the roof void and the wall void.
Patent CA-2900844-A1 (CA)
Inventor: BORELL HUBERT
IPC: G01N33/569
Filed: 2013-04-19
Abstract: The invention provides a method of assessing the appropriate therapeutic dose of 1-{4- [1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-ethyl-benzyl}-azetidine-3- carboxylic acid to administer to a patient in need thereof, comprising the steps of: (i) testing whether or not the patient has the poor metabolizer genotype; and (ii) if the patient does not have the poor metaboliser genotype, administering -{4-[1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-ethyl- benzyl}-azetidine-3-carboxylic acid, or a pharmaceutically acceptable salt thereof, to the patient at the standard therapeutic dose; and (iii) if the patient does have the poor metaboliser genotype, either (a) administering 1-{4-[1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)- ethyl]-2-ethyl-benzyl}-azetidine-3-carboxylic acid, or a pharmaceutically acceptable salt thereof, to the patient at a therapeutic dose below that of the standard therapeutic dose; or (b) not administering 1-{4-[1-(4-cyclohexyl-3-trifluoromethyl- benzyloxyimino)-ethyl]-2-ethyl-benzyl}-azetidine-3-carboxylic acid, or a pharmaceutically acceptable salt thereof, to the patient.
Patent CA-2902252-A1 (CA)
Inventor: BODIL VAN NIEL MONIQUE
IPC: C07C311/22
Filed: 2014-03-12
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, X1, X2, X3, X4, X5, X6, Y, Z, G, R1a, R2a, R1b, R2b, R3, R4, R5 and R6 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
Patent CA-2902342-A1 (CA)
Title: Neoseptins: small molecule adjuvants
Inventor: BEUTLER BRUCE
IPC: A61P37/00
Filed: 2014-02-25
Abstract: A MD-2:TLR4 complex agonist compound is disclosed whose structure corresponds to Formula (I), as defined within. Also disclosed are a method of its preparation and use, as well as a pharmaceutical composition containing the same.
Patent CA-2902491-A1 (CA)
Inventor: KIERNAN URBAN A
IPC: A61P3/00
Filed: 2014-02-25
Abstract: Provided herein are methods of increasing lipoprotein lipase (LPL) activity, by inhibiting apolipoprotein C3 (ApoCIII), which removes the ApoCIII inhibition of LPL, and permits VLDL to be converted to LDL. Also provided are methods for treating or preventing a lipid metabolism disorder, such as type 2 diabetes by use of an ApoCIII antagonist. Also provided are screening methods to identify ApoCIII antagonists.
Patent CA-2902508-A1 (CA)
Title: Systemes et procedes pour contenu de diffusion interactif
Inventor: FONSECA BENEDITO J JR
IPC: G10H1/36
Filed: 2014-03-07
Abstract: L'invention concerne des dispositifs et procédés pour noter des interactions de spectateurs avec un contenu diffusé sur un dispositif de présentation en traitant au moins un signal audio reçu par un microphone à proximité du spectateur et du dispositif de présentation, pour générer au moins une signature audio, qui est comparée à au moins deux signatures audio de référence différentes.
Patent CA-2902828-A1 (CA)
Inventor: ZEMEL MICHAEL
IPC: A23K1/18
Filed: 2014-02-25
Abstract: The present invention provides for systems, compositions, methods and kits for regulating energy metabolism in pets. The systems, compositions, and kits can comprise, and methods can make use of, pet foods, pet treats, pet supplements, and pet drinks. In one aspect, the invention provides for pet food, treat, supplement, and drink compositions that comprise a combination of (a) leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be effective for reducing weight or adipose volume in the pet. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising leucine, a leucine metabolite, and/or vitamin B6. The invention also provides for kits comprising compositions of leucine, a leucine metabolite, and/or vitamin B6 packaged in an oral dose form with usage instructions.
Patent CA-2904097-A1 (CA)
Inventor: FARMER DAVID E
IPC: G06Q30/02
Filed: 2014-03-14
Abstract: A computer program facilitates a consultation between an authorized user (20) and a human consultant (26). During the consultation, the human consultant maps a user need to one or more marketing objectives (42). The consultant interacts with the computer program to identify one or more tactics that are relevant to accomplishing the one or more marketing objectives (46). The consultant (26) or the user (20) selects from the one or more tactics identified by the computer program (48) to cause the computer program to identify marketing packages available to implement a selected tactic (50). The consultant (26) facilitates selection of a marketing package by the authorized user (20) to implement a selected tactic (52).
Patent CA-2904116-A1 (CA)
Inventor: PRONIUK STEFAN
IPC: C07J41/00
Filed: 2014-03-11
Abstract: Polymorphic forms of onapristone and methods of making and using such polymorphic forms are provided. Crystalline polymorphic forms can be characterized by their X-ray powder diffraction patterns and other properties.
Patent CA-2904649-A1 (CA)
Title: Wirelessly triggered smart media guides
Inventor: REINHARDT GERARD EDWARD
IPC: H04H20/61
Filed: 2014-03-13
Abstract: The invention is directed to wireless systems comprising one or more beacons that each emits a triggering data packet, and one or more smart media guides which upon receipt of a triggering packet, access the indicated track of digital content that has been preloaded into memory, and play that track through a user output interface. In some embodiments, each smart media guide transmits an SMG Identifier signal that can be received, stored and analyzed for purposes of understanding user behavior. In some embodiments, a transmitted content packet is transmitted by an exognenous source (such as a beacon or server-driven transceiver), received by a smart media guide, and stored for subsequent play. Beacon-based systems can be further used to trigger such things as alarms, lights, and various mechanisms. The invention has applications in such fields as tourism, marketing, demographic analysis, health care, pet care, safety and security.
Patent CA-2905621-A1 (CA)
Inventor: ZACHARIE BOULOS
IPC: C07C59/52
Filed: 2014-03-14
Abstract: The present invention relates to compounds of: or a pharmaceutically acceptable salt thereof, wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(0)-(CH2)n-CH3 or CH(OH)-(CH2)n-CH3 wherein n is 3 or 4; R1 is H, F or OH; R2 is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(0)-(CH2)n-CH3 or CH(OH)-(CH2)n-CH3 wherein n is 3 or 4; R3 is H, F, OH or CH2Ph; R4 is H, F or OH; Q is 1 ) (CH2)mC(0)OH wherein m is 1 or 2, 2) CH(CH3)C(0)OH, 3) C(CH3)2C(0)OH, 4) CH(F)-C(0)OH, 5) CF2-C(0)OH, or 6) C(0)-C(0)OH; and compositions comprising the same and the method using the same for the prevention or treatment of various fibrotic diseases and conditions in subjects, including pulmonary fibrosis, liver fibrosis, skin fibrosis, renal fibrosis, pancreas fibrosis, systemic sclerosis, cardiac fibrosis or macular degeneration.
Patent CA-2905889-A1 (CA)
Inventor: GOSSELIN MARK H
IPC: H04W4/16
Filed: 2014-03-11
Abstract: L'invention concerne des systèmes et des méthodes de distribution de données associées à un correspondant appelant un dispositif mobile, dans lesquels les données du correspondant appelant peuvent être présentées par le dispositif mobile lors de la réception d'un premier appel entrant du correspondant. Dans certains modes de réalisation, une image associée au correspondant appelant peut être obtenue par le dispositif mobile de façon que l'image soit affichée simultanément avec d'autres données de filtrage d'appel lors d'un premier appel entrant du correspondant. Dans certains modes de réalisation, la terminaison de l'appel entrant est conservée par un point de gestion de service pendant que les données sont transmises au dispositif mobile sur un canal de données. Un fois la terminaison de l'appel entrant libérée par le point de gestion de service, le dispositif mobile reçoit l'appel entrant et peut présenter les données comme informations de filtrage d'appel. Dans certains modes de réalisation, le canal de données peut comprendre un connecteur réseau toujours ouvert.
Patent CA-2909024-A1 (CA)
Inventor: ITOSHIRO HAJIME
IPC: A22C13/00
Filed: 2014-04-17
Abstract: The present invention provides a netted casing for foods in which the net is less apt to be separated from the nonwoven fabric and which can inhibit the inclusion of foreign substances and is an inexpensive packaging material. The netted casing (X) for foods comprises nonwoven fabric (1) and a net (2). The nonwoven fabric (1) comprises thermoplastic synthetic fibers, and the net (2) comprises a thermoplastic resin or thermoplastic synthetic fibers. The nonwoven fabric (1) and the net (2) are thermally laminated to obtain the netted casing (X) for foods.
Patent CA-2909086-A1 (CA)
Inventor: ZWIER DANIEL G
IPC: E04D13/04
Filed: 2015-10-14
Abstract: A rain water collection system for a blue roof system that includes a tray assembly comprising a container, a water absorbing layer located in said interior region of the container, ballast members and a cover plate. The water absorbing layer is supported on a first set of support surfaces to locate the water absorbing layer above the bottom wall of the container to provide a water collecting space into which will flow excess water that exceeds the water absorbing capacity of the water absorbing layer. The sidewalls of the container have openings therethrough to facilitate the passage of over flow water from the container and the introduction of air therethrough into the interior region. The upstanding columns have openings to facilitate the passage of air therethrough into the interior region of the container.
Patent CA-2909330-A1 (CA)
Title: Cutter device for marine survey system and related method
Inventor: LARSEN RAYMOND
IPC: B63B21/66
Filed: 2014-04-23
Abstract: Device, system and method for protecting towed marine survey equipment from line entanglement are provided. A cutter device (200) has a mounting mechanism (212) configured to fixedly attach at a predetermined position along a cable (210) used for towing, and one or more cutting structures(214,216,218). The cutting structures are attached to and extend away from the mounting mechanism, being configured to cut lines (230) that get caught by the cutting structures or slide along the cable to the predetermined position.
Patent CA-2912208-A1 (CA)
Title: Heterocyclic compounds as hedgehog signaling pathway inhibitors
Inventor: ARMER RICHARD
IPC: C07D401/04
Filed: 2014-05-28
Abstract: This invention relates to novel compounds of formula (I). The compounds of the invention are hedgehog pathway antagonists. Specifically, the compounds of the invention are useful as Smoothened (SMO) inhibitors. The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of the Hedgehog pathway and SMO, for example cancer.
Patent CA-2913757-A1 (CA)
Title: Systeme de plate-forme de bois modulaire
Inventor: WOLD MIKE
IPC: E01C9/08
Filed: 2014-05-30
Abstract: L'invention concerne un ensemble plate-forme incluant une poutre en bois lamellée incluant une première billette incluant un premier empilement de planches de bois mises à adhérer de façon adjacente, une pluralité des planches du premier empilement incluant une rainure s'étendant dans une première face de chaque planche, et une seconde billette incluant un second empilement de planches de bois mises à adhérer de façon adjacente, une pluralité des planches du second empilement incluant une languette s'étendant depuis une première face de chaque planche, les languettes du second empilement s'étendant dans les rainures du premier empilement et étant mises à adhérer sur ces dernières.
Patent CA-2913788-A1 (CA)
Title: Reflex coaxial illuminator
Inventor: PLUNKETT MALCOLM
IPC: A61F9/008
Filed: 2013-05-23
Abstract: A mirror for an ophthalmic laser treatment device that is movable on an axis from a position in a treatment laser beam path to a position out of the treatment laser beam path. The mirror reflects light from a light source into the eye of a patient. The mirror is biased towards a position in the path and is moved out of the path by an actuator just long enough for the laser treatment to be applied and without noticeable interruption to viewing by a user.
Patent CA-2916329-A1 (CA)
Inventor: STEFINOVIC MARIJAN
IPC: C07D487/04
Filed: 2014-07-04
Abstract: The present disclosure relates to polymorphic forms of the hydrochloride salt of ponatinib ("compound 1") and to processes for the preparation of these polymorphic forms. The present disclosure also generally relates to a pharmaceutical composition comprising the forms, as well of methods of using the form(s) in the treatment of disorders associated with pathological cellular proliferation, such as neoplasms, and cancer.
Patent CA-2917407-A1 (CA)
Title: Complexes containing albumin-containing nanoparticles and antibodies to treat cancer
Inventor: MARKOVIC SVETOMIR N
IPC: A61P35/00
Filed: 2013-09-30
Abstract: This document provides methods and materials related to treating cancer (e.g., skin cancer). For example, methods and materials relating to the use of a composition containing albumin-containing nanoparticle/antibody complexes (e.g., ABRAXANE®/anti-VEGF polypeptide antibody complexes) to treat cancer (e.g., skin cancer) are provided.
Patent CA-2919214-A1 (CA)
Inventor: MAUPAS-OUDINOT JEAN-BAPTISTE
IPC: A63F13/35
Filed: 2016-01-27
Abstract: The game system (2) comprises a computer server (4) able to implement at least one instant draw game, the computer server (4) being configured to perform several successive instant draws and to calculate winnings of the player at the end based on the results of the successive instant draws, wherein the computer server (4) is configured to command the display of data based on the result of a preceding instant draw, to detect an action by the player in response to the display of the data, to trigger an instant draw following the detection of an action by the player, and to command the display of subsequent data, the subsequent instant draw depending on the preceding instant draw and/or the action by the player, and the subsequent data depending on the following instant draw and/or the action by the player.
Patent CA-2921905-A1 (CA)
Title: Structure de carter interposee entre le moteur et la nacelle a platine a vis
Inventor: BELJAMBE CEDDRIC
IPC: F01D25/16
Filed: 2014-08-25
Abstract: Structure de carter d'un aéronef comportant : une virole entourant le moteur et comprenant une pluralité de secteurs (12A, 12B), plusieurs bras radiaux (14) chacun monté entre deux secteurs de virole adjacents et comportant chacun une base (14A), plusieurs moyens de fixation de ces secteurs de virole sur les bases des bras radiaux, ces moyens de fixation comportant plusieurs platines (20) montées chacune à effleurement dans des rainures (22) de forme correspondante aux secteurs de virole et un ensemble de vis à tête (26A-26D) maintenues captives de la platine par une différence de diamètre entre leur corps et leur filetage, un ensemble d'écrous prisonniers étant fixé sur les bases pour, en recevant chacun le filetage d'une vis captive de cet ensemble de vis à tête, assurer une liaison solidaire entre les secteurs de virole et les bras radiaux.
Patent CA-2926294-A1 (CA)
Inventor: SALAMONE JOSEPH CHARLES
IPC: C08F230/08
Filed: 2014-09-10
Abstract: Liquid adhesive coating materials are prepared that protect surfaces, such as medical devices and biological surfaces, including skin and mucous membranes, from pressure, shear, and friction. The liquid coating materials utilize an amphophilic siioxysilane/hydroxyaikyi ester polymer-containing coating material dissolved in a volatile solvent, with or without an antimicrobial agent, where when the polymer coating is formed after solvent evaporation and is folded against itself or placed against another material, the surface of said coating does not adhere, while the bottom of the coating remains attached to the original surface.
Patent CA-2926359-A1 (CA)
Inventor: ISHIHARA YOUICHI
IPC: G05B19/048
Filed: 2016-04-07
Abstract: A control system of the present invention includes a plurality of information acquisition apparatuses configured to acquire maintenance management information pieces having a unit of a predetermined time period, and a control apparatus configured to collect maintenance management information pieces from the information acquisition apparatuses. The information acquisition apparatuses each includes a first storage unit configured to store acquired maintenance management information, and a second storage unit forming a pair with the first storage unit. The maintenance management information stored in the first storage unit is saved into the second storage unit in response to a save command from the control apparatus. After maintenance management information pieces are saved from a first storage unit into a second storage unit in all of the information acquisition apparatuses, the control apparatus collects the maintenance management info/mation pieces saved in the second storage unit, from the respective information acquisition apparatuses.
Patent CA-2926569-A1 (CA)
Title: Method of producing weld joint
Inventor: KAMAGAI TATSUYA
IPC: B23K9/00
Filed: 2014-08-07
Abstract: The method of producing a weld joint according to the present invention involves performing a gas-shielded arc welding, using a flux-cored wire filled with flux into a steel sheath, on a steel plate having a predetermined Vickers hardness HV, a plate thickness, a C content, and a CEN, the method including: during the gas- shielded arc welding, not performing a preheating operation in a case where a temperature of the steel plate is 10°C or higher, and in a case where the temperature of the steel plate is lower than 10°C, performing the preheating operation so that the temperature of the steel plate is 10°C or higher, in which a weld metal of the weld joint has a predetermined chemical composition, a CEN of the weld metal is 0.20 mass% to 0.58 mass%, and an average Vickers hardness HV of the weld metal measured at 1 mm inward from a surface of the weld metal is 337 to 440.
Patent CA-2927751-A1 (CA)
Inventor: COLEMAN MICAH A
IPC: G09F9/30
Filed: 2016-04-20
Abstract: A wearable augmented reality overlay device for use with a tool displays information to a user relating to the status or operation of the tool, to the forming of a work piece for a project, or to safety information related to the tool. The displayed information may include a highlight projected onto a portion of the tool, onto a wearer's body part, or onto a work piece.  The displayed information may include a virtual control for the tool or another tool, an operating manual, or a maintenance, assembly or operating guide. The wearable display permits the user to control the tool and potentially other tools in the work shop. The display may instead include a projector to project adjustment information as a tool is adjusted. A  virtual image of a tool may be projected to locating a tool in a work area.
Patent CA-2927865-A1 (CA)
Inventor: MARLAND CHRISTOPHER NEIL
IPC: E21B47/12
Filed: 2013-12-23
Abstract: A method of operating a drill string comprises independently modifying a rotary speed of a downhole portion of the drill string relative to other downhole portions of the drill string, each of the portions comprising a plurality of drill pipe sections. The modified-speed portion of the drill string can comprise a downhole end portion of the drill string extending between a downhole drill string end and a curved portion of the borehole in which the drill string is located. The downhole end portion can be rotated at an increased speed relative to a portion of the drill string coincident with the curved portion of the borehole. Independent speed modification can be effected by incorporating one or more transmission modifier devices in the drill string, the transmission modifier device being switchable between a disengaged mode in which it transfers unmodified drill string torque and rotation, and an engaged mode in which it transmits torque and rotation along the drill string at a modified speed and torque. Selective switching of the transmission modifier devices, while downhole, maybe controlled from the surface.
Patent CA-2928014-A1 (CA)
Inventor: ARIEY FREDERIC
IPC: C12Q1/68
Filed: 2014-11-14
Abstract: K13-propeller polymorphism is a useful molecular marker for tracking the emergence and spread of ART-resistant P. falciparum. The invention encompasses methods, compositions, and kits for detecting and genotyping Plasmodium, for example, Plasmodium falciparum. The methods, compositions, and kits can be used to detect the presence or absence of a mutated K-13 propeller nucleic acid or protein in the sample.
Patent CA-2928429-A1 (CA)
Title: Aminoalkyl phenyl derivatives useful in the treatment of adhd and other cognitive disorders
Inventor: KORTAGERE SANDHYA
IPC: A61K31/137
Filed: 2014-10-28
Abstract: The present invention provides a method of treating or preventing an attention and/or cognitive disorder in a subject in need thereof, comprising administering to the subject a compound useful within the invention. The present invention further provides a method of treating or preventing dementia associated with a neurodegenerative disorder in a subject in need thereof, comprising administering to the subject a compound useful within the invention.