baber/WOPTO huggingface dataset:
Patent EP-0624152-B1 (EP)
Inventor: QUALLICH GEORGE J
IPC: C07C69/738
Filed: 1992-09-15
Granted: 1996-11-13
Abstract: A novel multi-step process for preparing the (4S &cir& _-enantiomer of 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone in a highly-optically pure form is disclosed. The process involves (1) first esterifying 4-(3,4-dichlorophenyl)-4-ketobutanoic acid with isopropylene or isobutylene to form the corresponding isopropyl or t &cir& _e &cir& _r &cir& _t &cir& _.-butyl 4-(3,4-dichlorophenyl)-4-ketobutanoate; (2) then reducing the ketobutanoic acid ester obtained in the first step with an asymmetric carbonyl reducing agent to form the corresponding chiral isopropyl or t &cir& _e &cir& _r &cir& _t &cir& _.-butyl 4-(3,4-dichlorophenyl)-(4R &cir& _)-hydroxybutanoate; (3) then sulfonylating the (4R &cir& _)-hydroxybutanoic acid ester with methanesulfonyl, benzenesulfonyl or p &cir& _-toluenesulfonyl chloride or bromide in the presence of a standard base to yield the corresponding isopropyl or t &cir& _e &cir& _r &cir& _t &cir& _.-butyl 4-(3,4-dichlorophenyl)-(4R &cir& _)-sulfonyloxybutanoate; (4) next subjecting the 4-sulfonyloxybutanoic acid ester obtained in the third step to a copper-coupling reaction with dilithium diphenyl(cyano)cuprate of the formula  PHI 2Cu(CN)Li2 to effect a stereochemical displacement of the organic (4R &cir& _)-sulfonyloxy group of the (4R &cir& _)-sulfonyloxybutanoic acid ester by the phenyl group of the dilithium diphenylcuprate reagent and so selectively form the corresponding isopropyl or t &cir& _e &cir& _r &cir& _t &cir& _.-butyl 4-(3,4-dichlorophenyl)-(4R &cir& _)-phenylbutanoate, and (5) thereafter cyclizing the stereospecific (4R &cir& _)-phenylated n-butanoic acid ester in the presence of a protic or Lewis acid catalyst to finally yield the desired (4S &cir& _)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone compound in a highly-optically pure form. The latter compound, which is a novel (4S &cir& _)-enantiomer per se, has utility as an intermediate that ultimately leads to pure c &cir& _i &cir& _s &cir& _-(1S &cir& _)(4S &cir& _)N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine (sertraline), which is a known antidepressant agent. The aforementioned isopropyl and t &cir& _e &cir& _r &cir& _t &cir& _.-butyl esters of 4-(3,4-dichlorophenyl)-(4R &cir& _)-hydroxybutanoic acid, as well as their corresponding (4R &cir& _)-methanesulfonyl, (4R &cir& _)-benzenesulfonyl and (4R &cir& _)-p &cir& _-toluenesulfonyl derivatives, are also novel compounds, as are the aforementioned isopropyl and t &cir& _e &cir& _r &cir& _t &cir& _.-butyl esters of 4-(3,4-dichlorophenyl)-(4R &cir& _)-phenylbutanoic acid as well as the aforesaid acid per se. These novel chiral compounds are all useful as key intermediates in the overall process of the present invention.
Patent EP-0607265-B1 (EP)
Title: Systeme et procede de regulation de carburant a boucle fermee
Inventor: GOFF EDWARD R
IPC: F02C9/28
Filed: 1992-10-09
Granted: 1996-05-08
Abstract: Système (100) de régulation de carburant permettant de réguler de manière précise le débit de carburant à un moteur (10) à turbine à gaz pendant les phases initiales de mise en marche. Le système de régulation de carburant présente une nouvelle boucle de commande fermée mesurant le débit effectif de carburant aux injecteurs primaires (22) du moteur (10), et il utilise cette mesure afin d'optimiser le signal de débit de carburant commandé, généré par des planifications préprogrammés dans l'unité de commande électronique (80) du moteur. Par le nouvel agencement d'unités de commande proportionnelle (114) et intégrée (118), le système de régulation (100) de carburant maintient un gain unitaire de chaîne d'action tout en permettant le réglage indépendant du gain des unités de commande afin d'atteindre une stabilité du système et une réponse nécessaire à une correction rapide des erreurs de débit de carburant.
Patent EP-0606397-B1 (EP)
Inventor: DEVER JAMES L
IPC: C08K3/22
Filed: 1992-10-05
Granted: 1999-06-16
Abstract: The present invention provides a reaction product of zinc oxide and pentaerythritol. The present invention also provides polymer blends stabilized with such zinc oxide and pentaerythritol reaction product and methods of producing stabilized polymer blends using the reaction product. More particularly, in one preferred form of the invention there is provided a method of producing a stabilized vinyl halide polymer blend comprising the steps of providing a vinyl halide polymer, providing a stabilizer system comprising the reaction product of zinc oxide and pentaerythritol, and mixing the vinyl halide polymer with the stabilizer system. The resultant stabilized vinyl halide polymer blend preferably comprises at least about 0.01 percent by weight of the reaction product of zinc oxide and pentaerythritol.
Patent EP-0565696-B1 (EP)
Inventor: GRINER CHRISTOPHER D
IPC: B01L3/00
Filed: 1992-10-27
Granted: 1996-09-11
Abstract: Un dispositif de support (14), où l'on range un plateau d'échantillons (12) pourvu d'un couvercle amovible (86), comprend une structure présentant une première (60) et une seconde ouverture d'accès (58) orientées en sens opposés. La première ouverture (60) permet au dispositif de recevoir le plateau (12) et le couvercle (86). Le dispositif de support (14) soutient le plateau (12) et le couvercle (86) dans un espace de rangement entre une paire de traverses (212) de support opposées. La seconde ouverture (58) reçoit un élément externe (24) qui se déplace verticalement dans la zone de stockage pour soulever le plateau (12) par rapport aux traverses (212), et qui se déplace horizontalement hors de la zone de stockage pour enlever le plateau (12) de cette zone par la seconde ouverture (58). Le dispositif de support (218) pivote le couvercle (86) par rapport au plateau de façon à maintenir le couvercle (86) en une position inclinée dans la zone de stockage, en l'absence du plateau, jusqu'à ce que celui-ci soit ramené à la zone de rangement.
Patent EP-0613607-B1 (EP)
Inventor: LAISNE ANDRE
IPC: H05H13/00
Filed: 1992-11-20
Granted: 1996-03-20
Abstract: Cyclotron isochrone compact (1) supraconducteur ou non supraconducteur dans lequel le faisceau de particules est focalisé par secteurs, comportant un électro-aimant constituant le circuit magnétique qui inclut au moins trois paires de secteurs (3, 3') appelés 'collines' oú l'entrefer est réduit, séparés par des espaces en forme de secteurs (4) appelés 'vallées' oú l'entrefer est de dimension plus grande et qui est énergétisé par au moins une paire de bobines (6) circulaires principales entourant les pôles de l'électro-aimant; ce cyclotron étant caractérisé en ce que l'entrefer (8) localisé entre deux collines (3, 3') présente un profil évolutif essentiellement elliptique qui tend vers la fermeture complète à l'extrémité radiale des collines (RC) sur le plan médian.
Patent EP-0566935-B1 (EP)
Inventor: FLACH WERNER DIPL-ING
IPC: H04L12/40
Filed: 1993-04-07
Granted: 1999-11-17
Abstract: The interface modules (4) of the present invention comprise two bus drivers (6) which are interconnected via an electronic system and are connected to the bus segments (1). In the present invention, the electronic system comprises two control circuits (15) which are separated from one another and two delay circuits (13) which interconnect the bus drivers (6). The control circuits (15) and the delay circuits (13) are constructed from low-cost standard components (14, 16-20). The interface modules (4) can therefore be implemented at extremely low cost. <IMAGE>
Patent EP-0584818-B1 (EP)
Inventor: VOGT-BIRNBRICH BETTINA DR
IPC: C08G18/08
Filed: 1993-08-26
Granted: 1998-12-02
Abstract: The coating composition contains:   I) from 40 to 100% by weight of a film former in the form of an aqueous dispersion of one or more polyurethane resins having a number average molecular weight (Mn) of from 2500 to 1,000,000 and a content of ionic groups, hydrophilic groups and/or groups which can be converted into ionic groups of from 5 to 200 meq per 100 g of solid resin, and at least one CH-acidic group per molecule and an OH number of from 0 to 100, where all or some of the CH-acidic groups can, for chain extension, be reacted with one or more compounds which are capable of reacting with at least two CH-acidic groups, and II) from 60 to 0% by weight of one or more crosslinking agents based on compounds which are capable of reacting with at least two CH-acidic groups, based on formaldehyde condensation resins and/or polyisocyanates containing free or blocked isocyanate groups, where the percentages by weight of I) and II) are based on the resin solids content and add up to 100% by weight, and optionally pigments, fillers, organic solvents and/or additives which are conventional in paints (surface coatings, lacquers, varnishes, enamels).
Patent EP-0597239-B1 (EP)
IPC: D03D47/34
Filed: 1993-10-04
Granted: 1996-05-29
Abstract: The invention relates to a device for the variable braking of running threads, wires or the like, especially for use during weft insertion on weaving machines, the thread (F) running through between two brake parts which can be brought into resilient bearing contact with one another and of which one forms a spring element and the other an abutment, and one of the brake parts being movable for the purpose of changing the braking. To improve the efficiency, provision is made for the abutment to be designed as an essentially cylindrical body (2) loaded rotatably by the spring element (1), with a first portion (4, 5) of essentially circular cross-section and with a second portion (8) having at least one circumferential region (6, 7) of reduced cross-section, the abutment being seated on the shaft (1) of an electric motor designed as a stepping motor (9). <IMAGE>
Patent EP-0599046-B1 (EP)
Inventor: FREIERMUTH PETER EDWARD
IPC: G01R31/26
Filed: 1993-10-18
Granted: 1999-01-27
Abstract: The described invention is directed to microwave methods for burning-in, electrical stressing, thermal stressing and reducing rectifying junction leakage current in fully processed semiconductor chips individually and at wafer level, as well as burning in and stressing semiconductor chip packaging substrates and the combination of a semiconductor chip mounted onto a semiconductor chip packaging substrate. Microwaves burn-in devices in a substantially shorter period of time than conventional burn-in techniques and avoid the need for special workpiece holders which are required by conventional stress and burn-in techniques. Additionally, microwave methods are described for reducing the leakage current of rectifying junctions, such as PN junctions and Schottky barrier diode junctions of semiconductor devices on fully processed semiconductor chips and wafers. <IMAGE>
Patent EP-0602351-B1 (EP)
Inventor: BERTAGNOLI RUDOLF DR MED
IPC: A61B17/70
Filed: 1993-10-22
Granted: 1999-03-10
Abstract: A device for repositioning vertebras of the human spine with at least a holding element to be mounted on a vertebra, comprising a yoke-like support placed on a base, said support including at least a pair of horizontally distant legs and a horizontal portion connecting said legs in the upper region, at least a tie element or pressure element mounted to said horizontal portion adjustable in height and preferably also adjustable sidewards, wherein the lower end of said tie or pressure element includes anchoring means for engaging said holding elements, characterized in that said support extending across the lying patient is provided with a pair of said legs (16, 18) which are supported along the longitudinal sides of a table, wherein the upper end each of said legs is connected through a cross piece (28). <IMAGE>
Patent EP-0606550-B1 (EP)
Inventor: HAENSCH EGON
IPC: B65H29/12
Filed: 1993-11-03
Granted: 1997-04-16
Abstract: Flat products (10) are fed to the reception region (18) by means of the conveying device (16). Arranged under the conveying device (16) is a transfer conveyor (22) which has individually controllable clamps (20) articulated on a wheel-like supporting member (30). The clamps (20) are controlled in such a way that, in the reception region (18), the clamp jaw (26) is directed forwards, as seen in the direction of rotation (U). In the reception region (18), the clamp (20) drops level with the product (10) and grasps the latter at the trailing edge (10'). During rotation about the axis of rotation (24) in relation to the transfer region (28), the clamp (20) is pivoted in the direction (S) opposite to the direction of rotation (U). In the transfer region (28), the products (10) are transferred to the processing device (12). <IMAGE>
Patent EP-0603910-B1 (EP)
Inventor: MIYAKAWA AKIRA
IPC: C04B28/06
Filed: 1993-12-24
Granted: 1997-04-02
Abstract: An ink refilling apparatus (15) for loading ink into a recording ink cartridge (1) having an ink discharging outlet (22), and an air vent (18) for communication with ambience includes a filling ink cartridge (33) for containing ink to be used for refilling the recording ink cartridge (1); a pressure controller (36) having a first pressure controlling portion (51) for controlling a pressure of the ink outlet and a second pressure controlling portion (52) for controlling a pressure of the air vent; a pressure transmitter (43) for transmitting a pressure variation of the second pressure controlling portion (52) to the filling ink cartridge (33). <IMAGE>   <IMAGE>
Patent EP-0538244-B1 (EP)
Inventor: DECKARD CARL R
IPC: B23K26/08
Filed: 1987-10-14
Granted: 1996-05-22
Abstract: A method and apparatus (10) for selectively sintering a layer of powder to produce a part comprising a plurality of sintered layers. The apparatus includes a computer (40) controlling a laser (12) to direct the laser energy onto the powder to produce a sintered mass. The computer either determines or is programmed with the boundaries of the desired cross-sectional regions of the part. For each cross-section, the aim of the laser beam is scanned over a layer of powder and the beam is switched on to sinter only the powder within the boundaries of the cross-section. Powder is applied and successive layers sintered until a completed part is formed. The powder may consist of a plastic, metal, ceramic, or polymer substance. In the preferred embodiment, the aim of the laser is directed in a continuous raster scan and the laser turned on when the beam is aimed within the boundaries of the particular cross-section being formed. Preferably, the powder dispensing mechanism includes a drum which is moved horizontally across the target area and counter-rotated to smooth and distribute the powder in an even layer across the target area. A downdraft system provides controlled temperature air flow through the target area to moderate powder temperature during sintering. <IMAGE>
Patent EP-0551957-B1 (EP)
Inventor: VAN DER LELY CORNELIS
IPC: A01K1/12
Filed: 1993-01-15
Granted: 1996-12-11
Abstract: An implement for milking animals comprises a milking machine with an arm (66) adapted to carry a number of teat cups (6), This arm (66) is rotatable about an upwardly directed axis relative to a holder (68), which holder (68) is in a fixed position in the implement. The teat cups (6) can be connected to the teats of the animal by hand and can be uncoupled automatically, without human labour, when the milk flow from the relevant udder quarters has stopped or has fallen below to a predetermined value.
Patent EP-0551204-B1 (EP)
Inventor: HARATS YEHUDA
IPC: H01M2/16
Filed: 1993-01-08
Granted: 1996-12-18
Abstract: The invention provides an electrochemical metal-air cell, adapted for multiple discharge and recharge cycles, comprising a housing defining an interior space for containing therein a replaceable metal electrode having a generally planar electrically conductive skeletal member encompassed by an active metal component; at least one generally planar air permeable but liquid impermeable air electrode installed at at-least one of the sides of the housing; an electrolyte in contact with the metal and the air electrodes; and further comprising one or more auxiliary electrodes, each auxiliary electrode constituting a charging anode adapted to be engaged upon application of electric current thereto for effecting the reduction and regeneration of the active metal component in a first mode of operation, during which the air electrode is disengaged, and to be disengaged in a second mode of operation, wherein the metal electrode is configured for removal from the interior space to enable the mechanical replacement thereof as well as being rechargeable in situ by the application of electric current to the auxiliary charging anode to reduce oxidized active metal thereof. <IMAGE>
Patent EP-0551229-B1 (EP)
Inventor: GROS JEAN-PIERRE
IPC: F01D11/12
Filed: 1993-01-07
Granted: 1996-11-27
Abstract: Drum rotor for an impulse steam turbine with the blades mounted in longitudinal grooves, and impulse steam turbine including such a rotor. 
<??>Drum rotor for an impulse steam turbine including movable wheels consisting of blades the roots of which, provided with flared parts, are immobilised in grooves made in the rotor, characterised in that the grooves are longitudinal over at least part of the rotor (6) and in that the roots (8) of the blades (9) of a movable wheel (10) are separated from the roots (8) of the blades (9) of a neighbouring movable wheel (10) by spacers (12). 
<??>Preferably, the diaphragms (15) are single-piece. 
<??>Optimum filling of grooves and better joining of the cap pieces of the blades. 
<IMAGE>
Patent EP-0555131-B1 (EP)
Inventor: PREVOST JACQUES
IPC: B30B9/32
Filed: 1993-02-01
Granted: 1995-11-08
Abstract: Press for compacting containers (28) of contaminated waste, comprising a frame including a base (1) and an upper crosshead (3) connected to the base by means of vertical supports (4), and a compacting assembly comprising a principal cylinder (5) linked to the upper crosshead (3), a principal piston (6), located in the said principal cylinder and determining a principal chamber (11) between the said piston and the upper end plate (10) of the said principal cylinder, the said principal piston being extended by a rammer rod (7), and a skirt (8) intended to surround the said container (28) at the time of the latter's compacting by the rammer, characterised in that the said skirt (8) is extended at its upper end by a tubular piston (9) accommodated in the said principal cylinder (5) between the latter and the said rammer rod (7) and determining an intermediate chamber (13) between itself and the principal piston (6) and an annular chamber (14) between itself and the lower end of the principal cylinder (5), the said principal chamber (11) and the said annular chamber (14) including pipes (12, 17) so that they can be supplied with control fluid, and in that the said intermediate chamber (13) includes a sliding leaktight device permitting its supply with control fluid. <IMAGE>
Patent EP-0640764-B1 (EP)
Inventor: HABEGGER OSKAR
IPC: F04B39/00
Filed: 1993-08-25
Granted: 1996-12-27
Abstract: The piston compressor comprises at least one cylinder (11) and a piston (10) which is guided therein in a non-contact manner and which is linked to a crosshead (6) via a piston rod (8). The piston rod consists of a tube (8) which extends between the crosshead (6) and the piston (10). In the tube there extends a tension rod (9) which can be extended by means of a hydraulic tensioning appliance (30) and which pulls, under pretension, the crosshead and the piston against the tube. <IMAGE>
Patent EP-0667919-B1 (EP)
Inventor: GUDIBANDE SATYANARAYANA R
IPC: C12Q1/68
Filed: 1992-12-07
Granted: 2001-09-26
Abstract: This invention relates to a new electrochemiluminescent (ECL) label for oligonucleotides using phosphoramidite chemistry.
Patent EP-0616536-B1 (EP)
Inventor: RUOSLAHTI ERKKI I
IPC: A61P17/02
Filed: 1992-12-04
Granted: 1999-03-17
Abstract: The present invention provides a method for treating or arresting the progress of pathologies characterized by an accumulation of extracellular matrix components by providing an agent to suppress the activity of transforming growth factor  beta  (TGF- beta ) a peptide growth factor which is anabolic and leads to fibrosis and angiogenesis. Pathologies which can be so treated include the various fibrotic diseases such as fibrotic cancer, fibrosis of the lungs, arteriosclerosis, post myocardial infarction, cardiac fibrosis, post-angioplasty restenosis, renal interstitial fibrosis, scarring and diabetic nephropathy. The present invention further provides methods for treating diabetes and pharmaceutical compositions useful in such methods.
Patent EP-0630514-B1 (EP)
Inventor: GARZAROLLI FRIEDRICH
IPC: G21C3/06
Filed: 1993-02-22
Granted: 1996-10-16
Abstract: L'élément combustible comprend une gaine constituée d'une couche intérieure plus épaisse (4) et d'une couche externe mince (5) liée métallurgiquement à celle-ci. La couche intérieure est composée, en raison des conditions de la face interne du tube de gainage et des propriétés mécaniques de tout le tube de gainage, de zircaloy ayant une teneur en étain relativement élevée et une faible teneur en fer et en fer + chrome. La couche extérieure ne contient elle aussi pratiquement que les composants du zircaloy. Pourtant, en raison de la corrosion, de l'absorption d'H2 et de la sensibilité au lithium dissous dans l'eau de refroidissement, la teneur en fer et en fer + chrome est supérieure ou à la rigueur égale à celle de la couche intérieure, la teneur en étain est inférieure à 1,3 % et la teneur en étain + fer + chrome est supérieure à 1 %. Cela permet également d'obtenir des taux réduits de défaillances du tube de gainage même lors de longs temps d'utilisation.
Patent EP-0624135-B1 (EP)
Inventor: LANG ARMIN
IPC: B62D5/22
Filed: 1993-02-04
Granted: 1996-06-12
Abstract: In a power-assisted rack and pinion steering gear, intended especially for motor vehicles, a pinion (2) in a steering box (1) is in engagement with a rack (6). A servo-motor (11) is coupled to the rack (6) to provide power assistance. The pinion (2) is fitted so as to pivot in a fixed bearing (3) and a loose bearing (4). In the region of the loose bearing (4) there are two control valves (26, 27), the axes of which are substantially perpendicular to that of the pinion (2). The loose bearing (4) is guided so as to move perpendicularly to its axis in the steering box (1) only in the direction of the axes of the two control valves (26, 27). In this power-assisted rack and pinion steering gear, the forces used to actuate the control valves are not the axial forces acting on the pinion (2) but the transverse forces. Thus the actuation of the control valves is independent of the helix angle of the pinion teeth.
Patent EP-0632759-B1 (EP)
Inventor: BACHER HELMUT
IPC: B29B13/10
Filed: 1993-03-16
Granted: 1996-12-18
Abstract: Un dispositif destiné à traiter des matières thermoplastiques, comme des déchets de polyester, comporte au moins deux récipients (1, 13) reliés en série, dans chacun desquels un outil de broyage et de mélange (5) tourne autour d'un axe vertical (4) dans la région du fond du récipient (1 et 13 respectivement). Au moins le récipient placé en aval comporte une conduite de vide (18) par laquelle un gaz protecteur peut être introduit, le cas échéant. Les récipients (1, 13) sont reliés l'un à l'autre par une tubulure (12) dans laquelle se trouve un organe d'arrêt (20), de manière à ceque le vide puisse être maintenu sans difficulté dans le récipient placé en aval (13), jusqu'à ce que la soupape d'arrêt (20) soit ouverte après que le vide du récipient (13) aspire la matière se trouvant dans le récipient placé en amont (1). Dans le récipient placé en amont (1) - vu dans le sens d'écoulement de matière plastique - il s'opère ainsi un prébroyage, un préchauffage, un préséchage et un précompactage de la matière plastique, ce qui est encore renforcé par le tourbillonnement produit lors de l'aspiration dans le récipient placé en aval (13). Un matériau parfaitement homogène peut ainsi être acheminé, pour traitement ultérieur, par une vis sans fin (16) raccordée au dernier récipient (13).