baber/WOPTO huggingface dataset:
Patent PT-1904635-E (PT)
Title: Glycosylated il-7, preparation and uses
Inventor: ASSOULINE BRIGITTE
IPC: A61K38/20
Filed: 2006-07-19
Abstract: The present invention relates to new and improved interleukin-7 polypeptides, as well as compositions comprising the same, their preparation and uses. The invention more particularly relates to hyperglycosylated IL-7 polypeptides having improved properties, as well as their manufacture and therapeutic uses. The invention also discloses novel IL-7 polypeptides having modified amino acid sequences containing artificially created glycosylation site(s), as well as corresponding nucleic acid molecules, vectors and recombinant host cells. The invention also relates to the use of such polypeptides, cells or nucleic acids for curative or preventive treatment of mammalian subjects, including human subjects.
Patent PT-2017560-E (PT)
Title: Rotary stirring device for treating molten metal
Inventor: SCHMEISSER DIRK
IPC: B01F23/00
Filed: 2007-07-05
Abstract: A rotary device for treating molten metal, said device comprising a hollow shaft at one end of which is a rotor, said rotor having:- 
a roof and a base, said roof and base being spaced apart and connected by a plurality of dividers; 
a passage being defined between each adjacent pair of dividers and the roof 
and base, each passage having an inlet in an inner surface of the rotor and an outlet in a peripheral surface of the rotor, each outlet having a greater cross-sectional area than the respective inlet and being disposed radially outward therefrom; 
a flow path being defined through the shaft into the inlets of the passages and out of the outlets; and 
a chamber in which mixing of the molten metal and gas can take place; 
wherein a plurality of first cut-outs are provided in the roof and a plurality of second cut outs are provided in the base, each of the first and second cut outs being contiguous with one of the passages.  The invention also resides in the rotor per se, a metal treatment unit for degassing and/or for addition of metal treatment substances comprising the rotary device of the invention and a method of treating molten metal using the device.
Patent PT-1865128-E (PT)
Title: Device for fixing a closing panel in the bottom of a rabbet of a column
Inventor: WILLOQUAUX MICHEL
IPC: E04H17/16
Filed: 2007-04-11
Abstract: The clip (3) has a support face (4) that is supported on a bottom (20) of a U shaped groove of a post. A passage (5) receives a unit that traverses the clip and the bottom of the groove. Slots permit the clip to enclose a vertical end wire and place the face in contact with the bottom. Metallic fins are spaced progressively from the support face towards an opposite face, and define a V shape whose opening is elastically deformable such that free ends of the fins cooperate with stops (10) of lateral fins (11) of grooves (1A, 1B) for temporarily anchoring the clip in the stops. An independent claim is also included for a fence constituted of panels whose ends are engaged in a groove of a post and comprising a fence panel`s vertical end wire maintenance clip.
Patent PT-2031602-E (PT)
Title: Conductive polyolefins with good mechanical properties
Inventor: DUPIRE MARC
IPC: H01B7/17
Filed: 2003-03-10
Abstract: This invention discloses a polymeric material reinforced with single-wall nanotubes (SWNT) or multiple-wall nanotubes (MWNT) with good electrical and mechanical properties. It also discloses a process for preparing said reinforced polymeric material and their use in electrically dissipative material.
Patent PT-2245405-E (PT)
Title: Gate unit and high temperature oven having the same
Inventor: BERNER KARL
IPC: F27D99/00
Filed: 2009-01-30
Abstract: The invention relates to a gate unit for gas-tight sealing of two adjacent high temperature zones within a high temperature oven, comprising a gate panel displaceable between an open position and a closed position within a guide structure. At least one sealing element is transported with the gate panel. Protecting means can be transported by the gate panel over at least one part of a transport path of the same, by which at least one segment of the sealing element can be protected over at least one part of the displacement path of the gate panel against influences harmful to the sealing element particularly against radiant heat. The invention further relates to a high temperature oven having an oven tunnel comprising a first high temperature zone and a second high temperature zone. The gate panel is disposed in a transition region between the first and the second high temperature zones.
Patent PT-660837-E (PT)
Inventor: ALTAMURA MARIA
IPC: C07D499/883
Filed: 1993-09-15
Abstract: Penem derivatives of general formula (I), below, and pharmaceutically acceptable salts thereof are disclosed.    <IMAGE>  (I)  wherein: R1 is H, C1-C6 alkoxy, C3-C7 cycloalkyl, or an optionally protected C1-C6 hydroxyalkyl; R2 is a free or esterified carboxyl group or a carboxylate anion; R3 is H or C1-C6 alkyl; R4 is H, C1-C6 alkyl, C1-C6 hydroxyalkyl, C1-C6 mercaptoalkyl, C1-C6 aminoalkyl, C1-C6 alkyl substituted by a quaternary ammonium group, C1-C6 carboxyalkyl, cycloalkyl, aryl, arylalkyl, heterocyclyl-alkyl optionally substituted, saturated or unsaturated heterocycle, or R3 and R4 are linked together to form a heterocyclic ring having 3-7 atoms; R5 and R6 independently are H, C1-C6 alkyl, C1-C6 hydroxyalkyl, C1-C6 mercaptoalkyl, C-C6 aminoalkyl, alkenyl, cycloalkyl, aryl, arylalkyl, alkylaryl, heterocyclyl-alkyl, C1-C6 alkyl carboxyamide, or R5 and R6 are taken together to form a heterocyclic ring having 3-7 atoms, and n is an intiger from 1 to 3.
Patent PT-711289-E (PT)
Inventor: CHANG KWEN-JEN
IPC: A61P11/00
Filed: 1994-07-29
Abstract: Diarylmethyl piperazine compounds having utility as exogenous receptor combinant species for binding with receptors such as delta, mu, sigma, and/or kappa receptors are disclosed. Compounds of the invention may be employed as conjugates in agonist/antagonist pairs for transductional monitoring and assays of neurotransmitter function, and also variously exhibit therapeutic utility, including mediating analgesia, and possessing utility for the treatment of diarrhea, urinary incontinence, mental illness, drug and alcohol addiction/overdose, lung edema, depression, asthma, emphysema, cough, and apnea, respiratory depression, cognitive disorders, emesis and gastrointestinal disorders.
Patent PT-736029-E (PT)
Inventor: COSTANZO MICHAEL J
IPC: C07D493/04
Filed: 1994-12-15
Abstract: A compound of general formula (I) is disclosed as a potent anticonvulsant drug. Pharmaceutical compositions and methods of treatment are also disclosed.
Patent PT-764443-E (PT)
Inventor: ENDO KOICHI
IPC: A61K31/59
Filed: 1995-04-18
Abstract: A drug for curing/ameliorating the concomitant syndrome of tumor which comprises a compound represented by the following general formula (I) as the active ingredient: <CHEM> wherein R1 represents an alkyl group having 1 to 10 carbon atoms and optionally substituted by one or more hydroxyl groups; and R2 represents a hydrogen atom or a hydroxyl group; is disclosed. This drug can be efficaciously employed in the treatment for the concomitant syndrome of tumor, in particular, cachexia or in the amelioration of the symptoms thereof.
Patent PT-762997-E (PT)
Inventor: BARRIS GLEN CLIFTON
IPC: C04B35/597
Filed: 1995-06-06
Abstract: PCT No. PCT/NZ95/00050 Sec. 371 Date Apr. 28, 1997 Sec. 102(e) Date Apr. 28, 1997 PCT Filed Jun. 6, 1995 PCT Pub. No. WO95/33700 PCT Pub. Date Dec. 14, 1995A process for the production of O'-SIALON ceramics from silicon metal, nitrogen and clay, the process comprising heating the silicon metal and the clay in a flowing nitrogen atmosphere to a temperature sufficient to react the components to form O'-SIALON and wherein the clay participates in the reaction as a source of aluminum and silicon.
Patent PT-744259-E (PT)
Inventor: FRATI LUIGI
IPC: B27N1/02
Filed: 1996-05-10
Abstract: The gluing machine, usable in plants for producing wood fibreboard panels by a dry process, comprises a hollow cylindrical shell, at one end of which there is provided an inlet opening for feeding an air stream transporting the fibres within which the glue is to be distributed, at the other end of the cylindrical shell there being provided an outlet opening for removing the air stream transporting the glue-impregnated fibres. A sprayer means is provided for spraying a suitable liquid adhesive substance onto the fibres flowing through the cylindrical shell. Means are also provided for maintaining the flowing fibres close to the inner wall of the cylindrical shell for a predetermined distance. The sprayer means is positioned within said distance in which the fibres are maintained close to the inner surface of the cylindrical shell. <IMAGE>
Patent PT-855884-E (PT)
Inventor: YAMAMOTO RONALD K
IPC: A61F2/28
Filed: 1996-10-15
Abstract: A porous three-dimensional tissue repair matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix.
Patent PT-840025-E (PT)
Inventor: KUSSER JOSEF
IPC: F16C32/06
Filed: 1997-10-28
Abstract: The disc-shaped object (1) is movably mounted in a cavity (5) in the holder (2) which has a feeder (3) for liquid, especially for water, near the cavity. The peripheral rim (1a) of the object is mounted in the cavity. The rim on the parts of the object next to the side surfaces (1b,1c) of the object are rounded. The rotary axis (4) of the object coincides with the axis of symmetry of the object and is horizontal. Between the object and the cavity is a gap preferably 0.1 to 2, and especially 02, millimetres wide. containing the liquid.
Patent PT-857688-E (PT)
Inventor: TATSUYA GOMI
IPC: F25D3/02
Filed: 1997-04-21
Abstract: The dispenser is to be installed on a beer keg (50) and has an outer shell body (2) with a truncated-cone shaped step bottom portion (9). A spiral cooling pipe (15) is fixed in a refrigerant receiver (12) inside the outer shell body (2). A dispense cock (3) at the outer periphery of the outer shell body (2) is connected to one end (15a) of the cooling pipe (15). The other end (15b) of the cooling pipe (15) is connected to a dispense head (13) fixed at a lower centre portion of the outer shell body (2) through a supporting plate (21). <IMAGE>
Patent PT-914148-E (PT)
Inventor: GESUNDHEIT NEIL
IPC: A61K38/00
Filed: 1997-04-18
Abstract: Methods of increasing the growth rate of a human patient having partial growth hormone insensitivity syndrome, but not Laron syndrome, are described. One such method comprises administering an effect dose of growth hormone, preferably growth hormone with a native human sequence, with or without an N-terminal methionine, to the patient. The patient is characterized as having a height of less than about -2 standard deviations below normal for age and sex, a serum level of high-affinity growth hormone binding protein that is at least 2 standard deviations below normal levels, a serum level of IGF-I that is below normal mean levels, and a serum level of growth hormone that is at least normal. In another such method, the same patient population is treated with an effective amount of IGF-I, given alone or in combination with an amount of growth hormone that is effective in combination with the IGF-I. <IMAGE>
Patent PT-937810-E (PT)
Inventor: MERLONI ANTONIO
IPC: D06F58/28
Filed: 1998-02-24
Abstract: A process for drying laundry, or the like, in washer-driers and driers, or the like, in which the laundry or the like, which has first undergone removal of a certain amount of water, for example by spinning, is subjected to the action of a stream of hot air while at the same time being agitated/moved to produce a lifting/tumbling of the laundry and greater exposure to the stream of hot air. The invention involves at least two, and preferably more, phases of movement of the laundry, or the like, alternating with pauses. During the phases of movement the laundry is subjected to a motion of movement/agitation which by speed and/or type of movement concentrates the said laundry in predetermined regions, leaving a considerable free volume for the passage of the hot drying air through the laundry containment vessel, and/or preferably forming a channel for the passage of the hot drying air around which the said laundry is distributed uniformly.
Patent PT-999826-E (PT)
Inventor: GAO PING
IPC: A61K31/4433
Filed: 1998-07-27
Abstract: Pharmaceutical composition comprises active, mixture of diglyceride and monoglyceride, solvents and surfactants. - Pharmaceutical composition comprises: (a) a lipophilic active agent; (b) a mixture of diglyceride and monoglyceride in a wt. ratio of 9:1-6:4 (diglyceride:monoglyceride); (c) >= 1 solvents and (d) >= 1 surfactant. The diglyceride and monoglyceride are mono- or di-unsaturated fatty acid esters of glycerol having a chain length of 16-22C. Also included is an INDEPENDENT CLAIM for a self emulsifying formulation vehicle for lipophilic active agents which comprises (b), (c) and (d) as above.
Patent PT-1190149-E (PT)
Inventor: HANNIG HANS-JURGEN
IPC: E04F15/04
Filed: 1999-10-09
Abstract: The slabs (2,3) have profiled edges (4,5) which lock together. The first edge has a tongue (6) which projects into a groove (20) in the second profile. The top part of the first edge (9) projects further forward than the bottom part (8). The bottom part (21) of the second edge projects further forward than the top part (22). The bottom surface (7) of the tongue on the first edge is convex and matches a concave portion (23) in the groove. The top surface of the tongue is horizontal at the root, then slopes gently downwards. The bottom of the groove is of rectangular cross-section.
Patent SG-6988-G (SG)
Title: Weldless joint
IPC: F16L41/00
Filed: 1988-02-02
Abstract: Apparatus providing a weld-free joint for intersecting pipes or tubes within a conduit system includes conduit means defining a first flow path extending in one direction and further conduit means defining a second flow path extending in a second direction which intersects said first flow path and has a releasable connection with said first conduit means embodying therein sealing means operative to preserve the integrity of said first flow path. In a preferred embodiment of the invention the releasable connection includes tubular means at least a portion of which intersects and bridges said first flow path and has a cross sectional dimension less than that of the cross sectional dimension of the interior of said conduit means which defines said first flow path.
Patent SG-44690-G (SG)
Title: Process for making substituted carboxylic acids and derivatives thereof
IPC: C10M133/52
Filed: 1990-06-22
Abstract: An improvement in known processes for preparing substituted carboxylic acids useful as acylating agents which comprise reacting (A) at least one aliphatic polymer of one or more lower olefins with (B) an acid reactant selected from the group consisting of fumaric acid, itaconic acid, maleic acid, and the corresponding anhydrides, lower alkyl esters, acyl chlorides and acyl bromides, in the presence of chlorine can be improved by the steps of (i) reacting at a temperature of about 100<o>-200<o>C, a mixture of (A) and (B) in the presence of about 0.05 to 0.15 equivalent of chlorine per equivalent of (A) until of the chlorine has reacted to provide a first intermediate product, (ii) continuing the reaction in the absence of chlorine at a temperature of from about 180<o>-250<o>C until a conversion of 0.4 to 1.1 equivalents of (B) per equivalent of (A) is attained to provide a second intermediate product, and (iii) reacting said second intermediate with about 0.2 to 1.5 equivalents of chlorine per equivalent of (A) used in step (i) at a temperature of about 180<o>-225<o>C. The carboxylic acids produced by this improved process can be used, per se, in lubricants and fuels and as acylating agents in reactions with amines, alcohols, reactive metals or reactive metal compounds to form derivative products which are useful, for example, as additives for lubricants and normally liquid fuels.
Patent SG-79691-G (SG)
Title: Method for rehabilitating concrete layers where a formation of carbonate has occured
IPC: E04G23/02
Filed: 1991-10-01
Abstract: Method for rehabilitating of concrete layers where formation of carbonate has occured, especially in connection with reinforced concrete and/or brickwall constructions. The surface of the concrete that is exposed to air is coated with a sealing layer (15), and the concrete layer (12) where formation of carbonate has occurred and the adjacent concrete (14) are supplied with water during a period of realkalization.
Patent SG-157194-G (SG)
Title: Lubricating oil viscosity additive method for preparing such an additive and lubricating compositions comprising the same
Inventor: GABILLET PHILIPPE
IPC: C10M133/12
Filed: 1994-10-25
Abstract: Viscosity additive containing:
 - 6 to 15 parts of a 60/40-54/46 ethylene/propylene copolymer of Mw 155,000 - 250,000 (OCP> - 2 to 8 parts of a poly(C1-C20 alkyl methacrylate) of Mw 30,000 - 150,000 (PMA) with a PMA/OCP ratio of 1/5 to 1/1
 - and the remainder to 100 parts of diluent oil. 
<??>Lubricating compositions containing 0.1 to 10% of the said additive.
Patent IE-780560-L (IE)
Title: Terpolymers of maleic anhydride, scale prevention
IPC: C08F220/04
Filed: 1978-03-21
Abstract: Terpolymers of maleic anhydride, acrylamide or methacrylamide and a third monomer consisting of octene, styrene and the like.
[US4065607A]
Patent IE-32108-L (IE)
Title: Horizontally hinged foldable door
IPC: E05D15/26
Filed: 1968-06-05
Abstract: 1,176,973. Doors. P. McGIRR. 18 Dec., 1967 [14 June,--1967], No.27431/67. Heading B7B. A door for a van is formed of two parts hinged together at 6 the upper part being hinged at 7 to a head-rail 1, and the lower part having rollers 9 engaging tracks ;l0 at the sides of the door opening. Coil springs 12 adjustably secured to the part 4 carry length adjustment members 14 provided with rollers 15 engaging a track 16 on the lower part of the door and the springs are biased bring the door parts into the position shown.
[GB1176973A]
Patent IE-810929-L (IE)
Title: Dental cream
IPC: A61K8/24
Filed: 1981-04-24
Abstract: An opaque dental cream is disclosed comprising an opacifying agent e.g. TiO2 a binary fluorine system e.g. NaF/Na2PO3F and a synthetic silica polishing agent such as aluminosilicates. The creams may also contain dicalcium phosphate and/or pearlescent flakes.
Patent IE-850965-L (IE)
Title: N-6 substituted adenosine derivatives, cardiac vasodilators
IPC: A61K31/70
Filed: 1985-04-16
Abstract: New, N-6 monosubstituted adenosine derivatives are disclosed which have significant cardiac vasodilatory effect. The compounds of the invention include 6-(cyclo-butyl amino) - 9 - ( beta -D-ribofuranosyl) - 9H - purine, 6 - (2 - methyl - 2 - phenyl hydrazino) - 9 - ( beta -D-ribofuranosyl) - 9H - purine, and compounds of the general formula: wherein R1 is H, lower alkyl, lower alkoxy, alkylamino, or arylamino, R2 is H, lower alkyl, hydroxymethyl, phenyl or substituted phenyl, R3 is H. lower alkyl, phenyl, substituted phenyl, R3 is H, lower alkyl, phenyl, substituted phenyl, 2- or 3-thienyl, or 2- or 3-pyridyl, R4 is H or lower alkyl, and R5 is H or lower acyl. Particularly active as a cardiac vasodilator is the compound (-) - 6 - (R - 1 - phenyl - 2 - butyl amino) - 9 - ( beta -D-ribofuranosyl) - 9H - purine.
Patent FI-813290-L (FI)
Inventor: OEDIGER HERMANN
IPC: C07F9/38
Filed: 1981-10-21
Abstract: The invention relates to phosphonoformaldehyde of the formula <IMAGE>   Also included in the invention is a method for the manufacture of said phosphonoformaldehyde in which a dialkoxymethane phosphonic acid is warmed with water (then reacted with a base if a salt is desired.) Phosphonoformaldehyde is an intermediate for the manufacture of phosphonohydroxy acetic acid, which is an antiviral agent.
Patent IE-801068-L (IE)
Title: Substituted acetophenones.
IPC: C07D235/08
Filed: 1980-05-22
Abstract: Compounds of the formula: <IMAGE> wherein R1 is hydroxy, phosphonooxy, aminoglycosyloxy, acylaminoglycosyloxy, benzyloxycarbonyloxy, arylcarbonyloxy, trialkylammonio-acyloxy or furoyloxy; R2 and R3 each are lower alkoxy; and R4 is benzimidazolyl, furyl which is unsubstituted or substituted with lower alkyl, thienyl which is unsubstituted or substituted with lower alkyl, or phenyl which is substituted with lower alkyl, lower alkoxy, alkoxyalkoxy, alkylthio, alkylenedioxy, or acyloxy, with the proviso that when R1 is hydroxy, R4 is benzimidazolyl or phenyl which is substituted by acyloxy or alkoxyalkoxy, or pharmaceutically acceptable salts thereof useful as antiviral agents.
[US4327088A]
Patent IE-881121-L (IE)
Title: Use of antigenic substances for the prophylaxis or therapy¹of disorders and diseases within the gastrointestinal tract¹of animals and humans
IPC: A61K39/00
Filed: 1988-04-14
Abstract: Disorders and diseases in human and animal digestive systems, for example diarrhoea, ulcerative disorders and carcinomas, are a serious, economically important problem worldwide. It was possible to show that immunological mechanisms exhibit a protective effect in the gastrointestinal tract of animals and humans. Antigens contained in the food induce the said protective mechanisms if the body has previously been sensitised to this antigen. The use of antigenic substances in the prophylaxis and therapy of ulcerative disorders in humans is preferred. The antigenic substances according to the invention are furthermore particularly highly suitable in the raising of young cattle, which are subjected to a change of food in the first weeks of life. <IMAGE>
[EP0286847A2]
Patent IE-841209-L (IE)
Title: Multi-layer amorphous magneto optical recording medium
IPC: G11B5/851
Filed: 1984-05-16
Abstract: A multi-layer magneto optical thin film recording medium is disclosed having very high carrier-to-noise ratios (at least 47 decibels) and high rotation angles. A transmission electron microscope photomicrograph (at 200,000 X) of one such medium is shown in FIG. 1. The magneto optic layer is a multi-phase amorphous material having magnetic anisotropy perpendicular to the plane of the thin film produced in a triode vacuum sputtering process at vacuums in the range of 4x10-3 to 6x10-4 Torr. Various transparent layers, such as dielectric intermediate and anti-reflective layers and a protective covering layer, are combined with the magneto optic layer and a reflective surface to yield media having enhanced carrier-to-noise ratio and magnetic optic angle of rotation.
[US4569881A]