baber/WOPTO huggingface dataset:
Patent CA-2401083-A1 (CA)
Title: Procede de preparation de triesters de phosphorothioate
Inventor: REESE COLIN BERNARD
IPC: C07F9/165
Filed: 2001-02-23
Abstract: L'inventif concerne un procédé de synthèse d'un triester de phosphorothioate, consistant à coupler un H-phosphonate avec un alcool, en présence d'une solution comprenant à la fois un agent de couplage et un agent de transfert de soufre. De préférence, le H-phosphonate et l'alcool sont des nucléosides ou oligonucléotides protégés.
Patent CA-2402652-A1 (CA)
Title: Viscoelastics for use in middle ear surgery
Inventor: DOSHI UDAY
IPC: A61K31/407
Filed: 2001-03-14
Abstract: Disclosed are viscoelastic compositions and methods of their use in surgical and non-surgical packing and in effecting drug delivery, especially in conjunction with trauma to or disorders of the ear.
Patent CA-2405235-A1 (CA)
Inventor: DUDA GEORG
IPC: A61B17/80
Filed: 2000-03-07
Abstract: La présente invention concerne un corps de guidage (1) permettant la réception d'éléments de fixation longitudinaux devant être fixés dans des os (10), tels que des fils, des clous, des broches ou des vis. Ce corps présente une face supérieure (3), une face inférieure (4), ainsi qu'au moins trois ouvertures (2) qui relient la face supérieure (3) et la face inférieure (4) du corps de guidage, les centres de ces ouvertures ne se trouvant pas sur une ligne droite. Les axes centraux (5) d'au moins deux des ouvertures (2) s'étendent de façon inclinée les uns par rapport aux autres. Le corps de guidage (1) permet l'insertion d'éléments de fixation (10) selon des angles divergents et permet leur croisement mutuel. Le corps de guidage (1) empêche principalement un déplacement, aussi bien vers la partie proximale que vers la partie distale, des éléments de fixation (10) s'étendant dans la zone intramédullaire ou dans la zone spongieuse.
Patent CA-2405265-A1 (CA)
Title: Method of preventing or treating diabetes
Inventor: LIU JINGXUE
IPC: A61K38/51
Filed: 2001-04-17
Abstract: A method for preventing, delaying the onset of or treating diabetes in a patient comprising selecting a patient who is susceptible to developing diabetes, who is developing diabetes or who is diabetic and administering to the patient one or more than one dose of a pharmaceutical agent comprising a polynucleotide encoding a secreted exogenous protein, such as a secreted luciferase or a secreted form of human glutamic acid decarboxylase.
Patent CA-2407395-A1 (CA)
Title: Method and apparatus for determining the left-ventricular ejection time tlve of a heart of a subject
Inventor: BERNSTEIN DONALD P
IPC: A61B5/029
Filed: 2002-10-10
Abstract: In order to reliably determine the left-ventricular ejection time T LVE of a heart of a subject, at least two different measuring methods are employed. This includes in any case the derivation of a first waveform related to thoracic electrical bioimpedance or bioadmittance. A second waveform can be determined by using pulse oximetry, Doppler velocimetry, measurement of arterial blood pressure and measurement of peripheral electrical bioimpedance or bioadmittance. Depending on signal quality, the results obtained by each method are weighted and then averaged. The weighted average for left-ventricular ejection time is used as an input variable for cardiovascular monitoring methods, which determine objective measurements of cardiovascular function and performance. Such measurements include, but are not limited to, left ventricular ejection fraction, stroke volume, cardiac output, systolic time ratio, and indices of ventricular contractility.
Patent CA-2408079-A1 (CA)
Title: Lock nut
Inventor: WINKER ALEXANDER
IPC: F16B37/00
Filed: 2002-10-15
Abstract: The invention relates to a lock nut (1) for bearing, especially a wheel bearing of vehicles, wherein the bearing has a universal shaft, introducing the torque via a splining, and a flange, which is axially secured to the universal shaft by a screw connection.  According to the invention they Lock nut (1) consists of a solid nut body (10), having a flange (11), from which extends axially a neck projection (12), being provided with an annular shroud (t3) at its end surface (14), from which at least two claws (15) extend radially.     (Fig.1)
Patent CA-2408865-A1 (CA)
Inventor: ROBERT PATRICE
IPC: C08F220/18
Filed: 2001-05-15
Abstract: The invention concerns polymers of formula (1) wherein: R¿1? represents an alkyl, cycloalkyl or aromatic radical capable of bearing one or several hydroxyl functions. They can be obtained by reacting a copolymer bearing an epoxy function on a side-chain with a product of formula R¿1?-COOH.
Patent CA-2409490-A1 (CA)
Inventor: BIEKER GUIDO
IPC: B61F5/30
Filed: 2001-05-10
Abstract: The invention relates to an undercarriage of a rail vehicle with radially adjustable wheelsets, comprising two spiral springs (5, 6) per bogie wheel (1) that are disposed at both sides of axle box case (3, 20, 21. The spiral springs (5, 6) are supported at their lower ends via at last one seat (7, 22, 23) of the axle box case (3, 20, 21). The upper ends of the said spiral springs (5, 6) exert pressure on inclined planes (10, 11) of a seat (12) of the undercarriage frame or bogie frame via friction wedges (8, 9). The lateral surfaces of said friction wedges (8, 9) facing the axle box case (3, 20, 21) exert a pressure on said axle box case (3, 20, 21).
Patent CA-2409575-A1 (CA)
Inventor: WHITE JACK D
IPC: E21B17/10
Filed: 2002-10-22
Abstract: A combined guide and automatic rod rotator device for a downhole sucker rod which is reciprocating axially. The sucker rod is connected with a swivel mechanism to allow rotational movement of the sucker rod. The combined guide and automatic rod rotator device includes a cylindrical body and at least two vanes extending radially from the cylindrical body, wherein the vanes are helically arranged on the body.
Patent CA-2413046-A1 (CA)
Inventor: PILIPENKO IGOR G
IPC: F03G3/00
Filed: 2002-12-10
Abstract: The Reaction-less Mover is a new device in the family of the mechanical movers. It works un the principle of the effect of Antigravity, which appears with the rolling the round and massive annular cylinder on the inclined plane upward, with its complete inertia.   In contrast to the known of gyro, inertia, and others machines. the Mover creates progressive impulse of motion without being repulsed from any material substance (ground, water, air). This impulse is created due to internal forces of the closed system.   This position makes it possible tin the new to glance at the field of application of a known law of physics since it completely corresponds to the laws of nature and is confirmed both theoretically and by the practically working model.     The Mover is intended to become alternative prime mover for water transport.
Patent CA-2417361-A1 (CA)
Title: Ethanolamines et ethylenediamines a substitution phenyle et phenylalkyle
Inventor: STRANSKY WERNER
IPC: A61P9/10
Filed: 2001-08-04
Abstract: Composés de formule générale (1) dans laquelle les restes A, R<1>, R<2>, R<3>, R<4>, R<5> et R<6> possèdent la signification figurant dans le descriptif et dans les revendications, procédé de production desdits composés et leur utilisation en tant que médicaments. Les composés de formule (1) ont pour effet de bloquer le canal sodique dépendant de la tension et peuvent être utilisés dans des maladies dont la cause est une perturbation fonctionnelle provoquée par une surexcitation.
Patent CA-2418752-A1 (CA)
Title: Glass fiber and thermoplastic resin composition
Inventor: NAKAGAWA HIDEKI
IPC: C03C3/21
Filed: 2003-02-12
Abstract: Glass fiber which substantially has the following composition as represented by mol percentage and has a glass transition temperature higher than 300°C and lower than 400°C:      Li2O+Na2O+K2O: 5 to 35% , P2O5 : 20 to 27%, SO3: 3 to 20%, ZnO: 10 to 55%, MgO: 0 to 20%, ZnO+MgO: 10 to 55%, Al2O3: 1 to 5%, and B2O3: 8 to 20%.
Patent CA-2419068-A1 (CA)
Title: Ring gear machine clearance
Inventor: HARLE HERMANN
IPC: F04C2/14
Filed: 2003-02-18
Abstract: The invention provides a ring gear machine with improved volumetric efficiency and reduced noise development. The machine comprises a casing with a gear chamber including a supply and a discharge of a working fluid. It further comprises a running set of at least one outer-toothed internal gear and one inner-toothed external gear in mesh with each other. The at least two gears comprise mutually eccentric rolling circle axes, whereas the internal toothing of the external gear comprises at least one tooth more than the external toothing of the internal gear. In the rotary drive action of one of the gears, the meshing toothings form expanding and compressing fluid cells for directing the working fluid from the supply to the discharge.
Patent CA-2420382-A1 (CA)
Title: A method for searching and analysing information in data networks
Inventor: OLSTAD BJORN
IPC: G06F17/30
Filed: 2001-09-11
Abstract: A method for providing searching and alerting capabilities in traffic content at access points in data networks is disclosed. Typical access points for Internet, intranet and wireless traffic are described. Traffic flow through an Internet Service Provider is used as a preferred embodiment to exemplify the data traffic used as the input source in the invention. The invention teaches how proper privacy and content filters can be applied to the traffic source.  The filtered data stream from the traffic flow can be used to improve the quality of existing searching and alerting services. The invention also teaches how a cache can be developed optimized for holding fresh searchable information captured in the traffic flow. It is further disclosed how the said cache can be converted to a searchable index and either separately or in cooperation with external search indexes be used as a basis for improved search services. The invention also discloses how the traffic flow can be analyzed in order to derive addes information for measuring document relevance, access similarity between documents, personalized ranking of search results, and regional differences in document accesses.
Patent CA-2420748-A1 (CA)
Inventor: AUGENSTEIN JOACHIM
IPC: E05F3/10
Filed: 2003-03-03
Abstract: A drive system for a moveable wing, especially for a door or a window, is described. The drive system includes at least one energy storage device by whose discharge of energy the wing is moved. The energy storage device is hereby controllable in its energy discharge by means of a control system. The control system has an electrically controllable control element. The motion of the wing is directly or indirectly detected by a sensor, whose output signal is fed into a regulating device, which controls the control element. The regulating device is realized in a way, that the influence of the control element, dependent on the motion of the wing, on the energy discharge of the energy storage device can be changed.
Patent CA-2421353-A1 (CA)
Title: Method for producing orthocarbonic acid trialkyl esters
Inventor: FISCHER ANDREAS
IPC: C25B3/23
Filed: 2001-09-05
Abstract: The invention relates to a method for producing orthocarbonic acid trialkyl esters by electrochemical oxidation of alpha-beta-diketones or alpha-beta-hydroxy ketones in the presence of C1-to C4-alcohols (alcohol A), the keto function being present in the form of a ketal function derived from C1- to C4-alykl alcohols and the hydroxyl function being optionally in the form of an ether function derived from C1- to C4-alykl alcohols (ketal K). The molar ratio of the ketal K to the alcohols A in the electrolytes is 0.2:1 to 10:1.
Patent CA-2422342-A1 (CA)
Title: Novel amide derivatives and medicinal use thereof
Inventor: KAMAHORI TAKAO
IPC: C07D317/58
Filed: 2001-09-14
Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action (see formula 1) wherein each symbol is as defined in the specification.     The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like]. Moreover, they are useful as a therapeutic or prophylactic agent for the infectious diseases caused by bacteria and virus that invade via a C5a receptor.
Patent CA-2423858-A1 (CA)
Inventor: NISHI YOSHISUKE
IPC: C12N1/21
Filed: 2001-09-27
Abstract: Tout comme les gènes codant des antigènes reconnus par un anticorps inductibles par G-CSF, les gènes de la présente invention codent les protéines suivantes : (a) une protéine présentant la séquence d'acides aminés représentée par SEQ ID NO:2 dans la liste des séquences; (b) une protéine présentant une séquence d'acides aminés dérivée de la séquence d'acides aminés représentée par SEQ ID NO:2 dans la liste des séquences par suppression, substitution, addition ou insertion d'un à plusieurs acides aminés et pouvant se lier à un anticorps ou à son fragment qui présente une activité d'induction/sécrétion du facteur de croissance hématopoïétique G-CSF (<i>granulocyte colony stimulating factor</i>) ; ou (c) une protéine présentant une homologie d'au moins 50 % par rapport à la séquence d'acides aminés représentée par SEQ ID NO:2 dans la liste des séquences et pouvant se lier à un anticorps ou à son fragment qui présente une activité d'induction/sécrétion du facteur de croissance hématopoïétique G-CSF.
Patent CA-2424026-A1 (CA)
Inventor: WINTER KAJ
IPC: A61K35/64
Filed: 2001-08-31
Abstract: L'invention concerne une composition contenant, comme ingrédients actifs, un extrait de pollen cytosolique soluble dans l'eau et/ou dans la graisse et éventuellement des pistils éventuellement associés à de la gelée royale et à la vitamine E pour produire un médicament destiné au traitement de la dysphorie liée aux variations hormonales normales chez la femme à l'âge de la fécondité, de la périménopause et de la post-ménopause.
Patent CA-2424040-A1 (CA)
Inventor: SMITH STEPHEN F
IPC: G01S1/06
Filed: 2001-09-26
Abstract: A short range radiolocation system and associated methods that allow the location of an item, such as equipment, containers, pallets, vehicles, or personnel, within a defined area. A small, battery powered, self-contained tag is provided to an item to be located. The tag includes a spread-spectrum transmitter that transmits a spread-spectrum code and identification information. A plurality of receivers positioned about the area receive signals from a transmitting tag. The position of the tag, and hence the item, is located by triangulation. The system employs three different ranging techniques for providing coarse, intermediate, and fine spatial position resolution. Coarse positioning information is provided by use of direct-sequence code phase transmitted as a spread-spectrum signal. Intermediate positioning information is provided by the use of a difference signal transmitted with the direct-sequence spread-spectrum code. Fine positioning information is provided by use of carrier phase measurements. An algorithm is employed to combine the three data sets to provide accurate location measurements.
Patent CA-2424590-A1 (CA)
Title: Improved membrane filtration system
Inventor: ROGERS PETER
IPC: B01D65/00
Filed: 2001-10-03
Abstract: A method and apparatus for reducing volume of feed liquid required in a poro us membrane filtration system having a number of porous membranes (6) submersed  in a volume of feed liquid to be filtered, the method comprising the step of  providing filler elements (9) within said volume of feed liquid to be filter ed.
Patent CA-2428514-A1 (CA)
Title: Resistant starch prepared by isoamylase debranching of low amylose starch
Inventor: SHI YONG-CHENG
IPC: A23L7/10
Filed: 2003-05-13
Abstract: This patent pertains to a resistant starch prepared by fully debranching a low amylose starch using isoamylase. Such resistant starch is useful in edible products, including nutritional supplements.
Patent CA-2428569-A1 (CA)
Title: Fluorescent lamp and amalgam assembly therefor
Inventor: CLEARY LOUISE D
IPC: H01J61/12
Filed: 2003-05-13
Abstract: An amalgam assembly for a fluorescent lamp includes a glass exhaust tubulation extending from an envelope portion of the lamp toward a base portion of the lamp, the tubulation being closed at an end adjacent the lamp base portion, and a glass body disposed in the tubulation and retained by a pinched portion of the tubulation, the glass body being disposed between the pinched portion and the closed end of the tubulation. A mercury amalgam body is disposed between the glass body and the closed end of the tubulation. A mercury wetting metallic layer is disposed on a selected one of (i) an inside surface of the tubulation between the pinched portion and the closed end of the tubulation, and (ii) a surface of the glass body whereby to a wet at least one of (i) the interior surface of the glass tubulation and (ii) the surface of the glass body, to prevent the amalgam, when liquidized, from flowing past the tubulation pinched portion and into the lamp envelope.
Patent CA-2430686-A1 (CA)
Title: Systeme de rincage
Inventor: GOSLIN DAVID L
IPC: E03B7/09
Filed: 2003-05-30
Abstract: L'invention porte sur un système de rinçage pour un système de distribution d'eau souterrain sous pression. Le système peut comprendre : un conduit d'admission pour recevoir l'eau sous pression du système de distribution d'eau souterrain; une sortie branchée de manière fluide au conduit d'admission afin d'évacuer l'eau sous pression dans le conduit d'admission vers le bas en direction d'un drain; et un robinet de réglage pour commander le débit de l'eau sous pression dans le conduit d'admission. Le système de rinçage comprend également, de préférence, au moins un élément du groupe d'un ensemble de protection contre le gel, d'un système de couplage amovible, d'un système de déchloration et d'un système de prévention du refoulement d'eau.
Patent CA-2430822-A1 (CA)
Inventor: DESHPANDE VIJAY A
IPC: C01B3/16
Filed: 2001-12-12
Abstract: An apparatus (10) for carrying out a multi-step process of converting hydrocarbon fuel (100) to a substantially pure hydrogen gas feed (150) includes a plurality of modules (128, 132, 136, 144) each module being in fluid communication with adjacent modules. The modules may be arranged axially along a common axis of flow or alternatively the modules are arranged along a common axis so that they are nested one within the other. The multi-step process includes: providing a fuel processor having a plurality of modules;  and feeding the hydrocarbon fuel (100) successively through each of the modules (128, 132, 136, 144) in the reactor to produce the hydrogen rich gas (150).
Patent CA-2435950-A1 (CA)
Title: Procede pour prevenir et traiter les douleurs viscerales et les affections gastro-intestinales
Inventor: CHOVET MARIA
IPC: A61K31/197
Filed: 2002-01-25
Abstract: Cette invention se rapporte à des composés représentés par les formules (I) à (IV), où n est égal à un nombre entier compris entre 1 et 4, ou à des sels de ces composés acceptables sur le plan pharmaceutique, qui sont utiles pour prévenir et traiter les douleurs viscérales et les affections gastro-intestinales.
Patent CA-2436551-A1 (CA)
Title: Thiazolyl-, oxazolyl-, pyrrolyl-, and imidazolyl-acid amide derivatives useful as inhibitors of pde4 isozymes
Inventor: MCKECHNEY MICHAEL WILLIAM
IPC: C07D277/56
Filed: 2001-12-24
Abstract: Compounds useful as inhibitors or PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of the formula (I), where j is 0 or 1; k is 0 or 1; m is 0, 1, 2 or 3; n is 1 or 2; W1 is -O-; or -S(=O)t-, where t is 0, 1 or 2; or -N(R3)-; W2 is -O-CRARB- or is absent; Y is =C(R1a)- or -[N.rArr.(O)k]- where k is 0 or 1; RA and RB are -H; -F; -CF3; -(C1-C4) alkyl; -(C3-C7) cycloalkyl; phenyl; or benzyl substituted with 0 to 3 substituents R10; or RA and RB are taken together, but only in the case where m is 1, to form a spiro moiety; RC and RD have the same meaning as RA and RB  except that one of them must be -H, R1 and R2 are -H; -F; -CI;- CN; -NO2; -(C1-C4) alkyl; -(C2-C4) alkynyl; fluorinated -(C1-C3) alkyl; -OR16; and -C(=O)NR22aR22b; R3 is H; -(C1-C3) alkyl; phenyl; benzyl; or -OR16; R4, R5 and R6 in addition to other meanings may be taken together to form formula (II), G1 is a saturated or unsaturated carbon ring system; where optionally one carbon atom may be replaced by a heteroatom selected from N, O, and S; -G2 is a saturated or unsaturated carbon ring system; wherein one carbon atom of may be replaced by a heteroatom selected from N, O, and S; and E is selected from formula (III).
Patent CA-2436599-A1 (CA)
Title: Oral pharmaceutical compositions comprising polyvinylpyrrolidone (pvp) and 5-cnac
Inventor: YANG REBECCA FAI-YING
IPC: A61P3/14
Filed: 2001-12-05
Abstract: Solid pharmaceutical compositions suitable for the oral delivery of pharmacologically active agents, e.g. peptides, comprising a therapeutically - effective amount of a pharmacologically active agent; a crospovidone or povidone; and a delivery agent for said pharmacologically active agent are disclosed. The compositions provide excellent oral bioavailability of pharmacologically active agents, particularly calcitonin.
Patent CA-2436811-A1 (CA)
Title: Utilisation de chromanes
Inventor: HORVATH ERVIN
IPC: A61P25/16
Filed: 2002-01-03
Abstract: L'invention concerne l'utilisation de 1,1-dioxyde de 2-[4-({[(2R)-8-isopropoxy-chroman-2-yl]méthyl}amino)butyl]-1,2-benzisothiazol-3(2H)-one, de ses sels, hydrates ou solvates physiologiquement acceptables, notamment de son hydrochlorure, pour la production d'un médicament servant à la prophylaxie ou au traitement de la maladie de Parkinson.
Patent CA-2437023-A1 (CA)
Title: Radiation thermometer comprising a heated measuring tip
Inventor: KLOES ALEXANDER
IPC: G01K13/00
Filed: 2002-02-19
Abstract: The invention relates to an infrared thermometer, especially an ear thermometer for measuring temperature, comprising an infrared sensor, a measuring tip which can be heated by a heating element, an actuating device which can be operated by a user, a control device and a display device. The invention also relates to a method for measuring temperature, especially by means of a radiation thermometer having a heatable measuring tip. Said control device switches off the heating element after the user has actuated an actuating device. After a certain amount of time, a plurality of temperature measurements are successively carried out, and the temperature to be displayed is determined from said measured temperatures or an error message is generated. At the latest, after a maximum measuring time has elapsed or after a maximum number of temperatures have been measured, the temperature to be displayed or an error message is displayed on the display device.
Patent CA-2442149-A1 (CA)
Title: Viral vectors
Inventor: GRIFFIN STEPHEN DANIEL CHARLES
IPC: A61K48/00
Filed: 2002-03-28
Abstract: A Human Immunodeficiency Virus (HIV-2) vector having a mutation within a packaging signal such that viral RNA is not packaged within an HIV-2 capsid is described. A further vector comprises an HIV-2 packaging signal and a heterologous gene capable of being expressed in the vector. These vectors ma y be co-transfected into a host cell to produce HIV-2 virus particles capable of expressing a heterologous gene.