baber/WOPTO huggingface dataset:
Patent CA-2672238-A1 (CA)
Title: Aminoalcohol derivatives and their therapeutic use
Inventor: LASTERRA ELENA
IPC: C07D309/08
Filed: 2007-12-12
Abstract: A compound of formula (1 ) Including pharmaceutically acceptable salts thereof, wherein: R1 is aryl or heteroaryl optionally substituted with R8; R2 is H or alkyl or CH2 (when forming part of a ring with R3, R4 or R5); R3 is H, alkyl, CH2OH or CH2OR6 and can be part of a ring with R2; R4 is H, alkyl, CH2OH or CH2OR6 and can be part of a ring with R2; R5 is H, alkyl, CH2OH or CH2OR6 and can be part of a ring with R2; R6 is H, alkyl, COH, COOR9, CON(R9)2, COR9, COR10, COR11, P(O)nR9, P(O)nR10S(O)nR10 or S(O)nR9and can be part of a ring with R2, R3, R4 or R5; R7 is H, alkyl, COOR9, COOR11, COR9 or CON(R9)2, and can be part of a ring with R2, R3, R4, R5 or R6; R8 is alkyl, CF3, OR9, OCOR9, CONH2, CN, F, Cl, Br, I, N(R9)2, NO2, NHCHO, NHCONH2, NHSO2R9, CON(R9)2, S(O)nR9, CH2OH Or OCON(R9)2; R9 is H, alkyl or cycloalkyl; R10 is aryl or heteroaryl (optionally substituted with R8) or a four to seven membered ring (which is optionally substituted with R8 and can contain one or more additional heteroatoms selected from the list O, S(O)n and NR9); R11 is alkyl optionally substituted with R8 or R10; and n is O, 1 or 2; provided that when R3, R4 or R5 is CH2OH then R6 is not H, and that when R7 is H and R3, R4 and R5 are alkyl then R6 is not H. is of therapeutic use in the treatment of a condition associated with T-cell proliferation or that is mediated by pro- and/or anti-inflammatory cytokines.
Patent CA-2672421-A1 (CA)
Title: Operating unit with touchscreen keys
Inventor: WERFELI FRIEDRICH
IPC: G06F3/0488
Filed: 2007-12-10
Abstract: The novel invention relates to a method and an apparatus for controlling one or more machines or a production cell with repeatable sequences using a machine controller, and to an operating unit in the form of a man-machine interface (MMI). The novel invention proposes making at least some of the operative control inputs for machine movement using haptic keys which can be programmed for their function and are applied to a screen and/or tactile touchscreen keys which can be seen and sensed, for example with an edge which can be sensed, with a respective associated screen field. The operator is thus provided with a guide function for operation, whether by the fact that he haptically senses the keystroke, for example via snap domes, or by the fact that he only tactually feels an edge around the screen key.
Patent CA-2673770-A1 (CA)
Inventor: RINCKEL LORI A
IPC: C12P19/34
Filed: 2008-01-15
Abstract: Nucleic acid molecules derived from sequences of novel human parvovirus B19 variant genomes are provided. Also provided are assays and kits comprising the nucleic acid molecules.
Patent CA-2677331-A1 (CA)
Title: Substituted benzodiazepinones, benzoxazepinones and benzothiazepinones as sodium channel blockers
Inventor: DUFFY JOSEPH L
IPC: A61K31/55
Filed: 2008-02-25
Abstract: The present invention is directed to substituted benzodiazepinones, benzoxazepinones and benzothiazepinones compounds that are sodium channel blockers useful for the treatment of chronic and neuropathic pain. The compounds of the present invention are also useful for the treatment of other conditions, including disorders of the CNS such as anxiety, depression, epilepsy, manic depression and bipolar disorder. This invention also provides pharmaceutical compositions comprising a compound of the present invention, either alone, or in combination with one or more therapeutically active compounds, and a pharmaceutically acceptable carrier. This invention further comprises methods for the treatment of acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain and disorders of the CNS including, but not limited to, epilepsy, manic depression, depression, anxiety and bipolar disorder comprising administering the compounds and pharmaceutical compositions of the present invention.
Patent CA-2677483-A1 (CA)
Inventor: REAP JAMES J
IPC: A01N25/04
Filed: 2008-02-28
Abstract: Disclosed are single liquid-phase herbicide compositions comprising by weight from 0.1 to 30% of one or more sulfonylurea herbicides, from 0 to 40% of one or more biologically active agents other than sulfonylurea herbicides, from 0 to 30% of one or more herbicide safeners, from 10 to 99.9% of one or more polyalkoxylated triglycerides wherein no more than about 50% by weight of the fatty acid-derived moieties in the polyalkoxylated triglycerides are derived from hydroxy fatty acids, from 0 to 89.9% of one or more fatty acid esters of C1-C4 alkanols, and from 0 to 70% of one or more additional formulating ingredients.
Patent CA-2677513-A1 (CA)
Inventor: MAIER FERDINAND
IPC: G08C19/00
Filed: 2009-09-02
Abstract: A multimedia assembly with a programmable universal remote control unit, which is configured to "learn" remote control codes from original remote control units, provides that remote control signals are transmitted from original remote control units (6-14) to the control unit (5) where they are analyzed, decoded, and newly encoded. The newly encoded signals are then transmitted from the control unit (5) to the universal remote control unit (15) that is to be programmed, where they are stored in a memory.
Patent CA-2678483-A1 (CA)
Inventor: KIM YOUNG-SAM
IPC: D04H1/4374
Filed: 2008-02-11
Abstract: A composite structure including a substrate and a fluid in contact with the substrate, wherein the substrate comprises a non-woven, a foam, or combinations thereof and is characterized by having a basis weight of 15 to 500 grams per square meter.
Patent CA-2680201-A1 (CA)
Inventor: JABLONSKI GREGORY A
IPC: B32B5/16
Filed: 2008-02-29
Abstract: Disclosed are cohesive metallic structures, comprising sintered metallic nanoparticles, suitable for shielding against electromagnetic interference and radio frequency interference. Also disclosed are methods for forming such structures. Devices for shielding electromagnetic radiation and methods of shielding electromagnetic radiation using such devices are also provided.
Patent CA-2680612-A1 (CA)
Title: Improvements in or in relation to locking devices
Inventor: HOWARTH LEON TROY
IPC: E05B51/02
Filed: 2008-03-17
Abstract: A tool carrier assembly (100) comprising a main body (101), a quick hitch (102), and a rotatable locking device (103) between the quick hitch and the main body. The rotatable locking device employs releasable locking means (104,105) at opposite ends. A scroll plate (106), cylinder (107) and piston (108) which upon assembly is located inside the cylinder) are located between the releasable locking means (104,105). In normal operation the piston (108) is driven back and forth to tilt the hitch by reason of rotation of the cylinder as guide (109) travels in the helical guide way (110) of the scroll plate (106). The hitch is fixed to the cylinder and the main body is fixed to the scroll plate. The releaseable locking means (104) and (105) each comprise an internally tapered end cup (111), bearing (112), an unlock piston (113), a locking element (114) and a locking spring (115). The springs (115) bias the locking elements into the internal taper of the end cups (111) against the piston (113), the cylinder in this embodiment has an outward taper so the locking element wedges in as shown. In order to change the relative position of the tool and the main body the assembly must be unlocked, the pistons (113) are displaced toward each other releasing the locking elements and freeing the cylinder, the cylinder and piston are a double acting cylinder assembly so as fluid flows into and out of each side as desired the cylinder will rotate, upon reaching the required angle the unlocking fluid is relieved and the springs lock the assembly.
Patent CA-2680797-A1 (CA)
Title: Systems and methods for portable personalized radio
Inventor: KINDIG BRADLEY
IPC: H04L29/08
Filed: 2008-03-13
Abstract: Systems and methods for delivering personalized content streams over a variety of devices and networks are disclosed. A user's preferences, customizations, and content are made available to the user through specialized clients for home, car, office, and portable environments. In order to enable personalized content streams on devices that are intermittently connected or that make use of network bandwidth during off-peak hours, the system prescribes a distributed content sequencing engine and a distributed, synchronized user profile and station/channel definitions. The system is also designed to support players connected via unidirectional or asymmetric connections such as satellite radios with or without an upstream data link.
Patent CA-2685567-A1 (CA)
Inventor: HACKER ERWIN
IPC: A01N25/32
Filed: 2008-04-16
Abstract: Compounds of the formula (I), or salts thereof: (see formula I) are suitable as useful-plant-protecting agents for reducing or preventing harmful effects of agrochemicals on the useful plants. Processes for preparing the compounds are also provided.
Patent CA-2685857-A1 (CA)
Title: Systemes hydrodynamiques pour l'assistance ecoenergetique d'un edifice, procedes de construction et utilisations correspondants
Inventor: LAPERLE DOMINIC
IPC: E04H5/00
Filed: 2009-11-18
Abstract: Systèmes hydrodynamiques pour l'assistance éco énergétique d'un édifice domiciliaire, commercial et/ou industriel comportant au moins un bassin hydrodynamique proportionnel à force inertielle, un dispositif de récupération et de redirection dans ledit bassin hydrodynamique d'un liquide récupéré, un dispositif d'évacuation de la masse thermique liquide vers l'extérieur de l'édifice et/ou vers les éléments sanitaires dudit édifice; et un dispositif permettant l'échange thermique entre la masse thermique liquide présente dans l'élément de stockage dudit bassin hydrodynamique et les éléments de chauffage et/ou de réfrigération présents dans ledit édifice. Ces systèmes sont construits notamment par mise en oeuvre de techniques connues et sont utilisés pour la réduction de la consommation en eau potable et/ou comme réservoir d'eau additionnel utile notamment en cas d'incendie.
Patent CA-2688553-A1 (CA)
Inventor: TOUBOUL SHLOMO
IPC: G06F21/24
Filed: 2008-06-01
Abstract: A computer performs dynamic address isolation. The computer comprises an application associated with an application address, a network interface coupled to receive incoming data packets from and transmit outgoing data packets to an external network, a network address translation engine configured to translate between the application address and a public address, and a driver for automatically forwarding the outgoing data packets to the network address translation engine to translate the application address to the public address, and for automatically forwarding the incoming data packets to the network address translation engine to translate the public address to the application address. The computer may communicate with a firewall configured to handle both network-level security and application-level security.
Patent CA-2689693-A1 (CA)
Inventor: MUTA KENJI
IPC: G01W1/00
Filed: 2004-09-28
Abstract: Provided is a gas flux measuring device measuring a region, such as forest, as a measuring object with no influence by concomitants and with high responsibility and excellent measuring stability. The device comprises a laser beam source, laser output controller, wavelength modulation controller, first light receiver, first direct current component detector, first wavelength modulation demodulator, optical system, reference cell, second light receiver, second direct current component detector, second wavelength modulation demodulator, third wavelength modulation demodulator, analyzer, adder, temperature measuring means and pressure measuring means. The device further comprises a flow velocity measuring means directly measuring horizontal 2-directional flow velocity components and a vertical directional flow velocity component of a gas flow in the measuring region and putting out these measurement signals into the analyzer. Based on the signals inputted from the flow velocity measuring means, the analyzer makes analysis based on the eddy correlation method and obtains, by calculation using this analysis result, a momentum flux and concentration of the measuring object gas.
Patent CA-2691267-A1 (CA)
Inventor: GARCIA MARIA L
IPC: C12Q1/16
Filed: 2008-06-25
Abstract: A novel use for MDCK cells in the evaluation of cholesterol modulators is provided. In particular, methods for detecting substances which bind to NPC1L1 and block intestinal cholesterol absorption are provided. Such substances are of use in the treatment of individuals with hypercholesterolemia. The various assays may additionally be employed for studying NPC1L1 function.
Patent CA-2691540-A1 (CA)
Title: Stimuli responsive nanofibers
Inventor: WEN JIE
IPC: A61L27/34
Filed: 2008-06-20
Abstract: A stimuli responsive nanofiber that includes a stimuli responsive polymer, such as a thermally responsive polymer, and a cross-linking agent having at least two latent reactive activatable groups. The nanofiber may also include a biologically active material or a functional polymer. The stimuli responsive nanofiber can be used to modify the surface of a substrate. When the nanofiber includes a thermally responsive polymer, the physical properties of the surface can be controlled by controlling the temperature of the system, thus controlling the ability of the surface to bind to a biologically active material of interest.
Patent CA-2691660-A1 (CA)
Inventor: DAVENPORT FRANCIS L
IPC: D21F7/08
Filed: 2008-06-04
Abstract: The present invention relates to a process of obtaining an industrial fabric with porous and controlled plasticized surface and an industrial fabric with the mentioned characteristics thereof.  The invention also relates to an industrial fabric such as press fabric for use in the press section of a paper machine with enhanced aesthetic properties by the use of plasticizers and optional heat and/or pressure treatment.
Patent CA-2691666-A1 (CA)
Inventor: MIRANDA FERNANDO CARLOS
IPC: H04L9/00
Filed: 2008-06-26
Abstract: The present invention provides a system and method for providing computer net-work attack simulation. The method includes the steps of: receiving a network configuration and setup description; simulating the network configuration based on the received network configuration; receiving at least one confirmed vulnerability of at least one computer, machine, or network device in the simulated network; receiving a method for compromising the confirmed vulnerability of the at least one computer, machine, or network device; and virtually installing a net-work agent on the at least one computer, machine, or network device, wherein the network agent allows a penetration tester to execute arbitrary operating system calls on the at least one computer, machine, or network device.
Patent CA-2693729-A1 (CA)
Inventor: KAMAT HARSHAD N
IPC: G06F17/30
Filed: 2010-02-19
Abstract: A communications system may include at least one data storage device configured to store electronic messages and record identifications (IDs) therefor in respective accounts, and a plurality of mobile wireless communications devices each associated with a respective account. The system may further include at least one polling server configured to perform polling requests of the at least one data storage device and retrieve therefrom respective record IDs for each account, with each polling request being for a selectable number of record IDs. The polling server(s) may also be configured to selectively change the number of record IDs in each polling request based upon an estimated number of electronic messages stored in a respective account, and cause electronic messages to be delivered to respective mobile wireless communications devices based upon the record IDs.
Patent CA-2693922-A1 (CA)
Inventor: TOWSON JAMES C
IPC: C07D263/14
Filed: 2008-07-22
Abstract: A method of preparing oxazolidine-protected and oxazolidinone-protected aminodiol compounds is disclosed.  These compounds tend to be useful as intermediates in processes for making Florfenicol and related compounds.
Patent CA-2694003-A1 (CA)
Inventor: NIJSEN JOHANNES FRANCISCUS WILHELMUS
IPC: A61K49/00
Filed: 2008-07-18
Abstract: The invention provides a microsphere comprising an organic lanthanide metal complex wherein the lanthanide metal is present in an amount of more than 20 wt%, based on total microsphere. The invention further provides a suspension comprising such a microsphere. In addition, the invention relates to a method for preparing said microsphere, and the use of the microsphere (s) or suspension for treating a malignancy and/or obtaining a scanning image.
Patent CA-2694474-A1 (CA)
Title: Nouveaux derives fluorescents de polyamines, leur procede de preparation et leurs applications en tant qu'outils de diagnostic dans le traitement des tumeurs cancereuses
Inventor: ANNEREAU JEAN-PHILIPPE
IPC: G01N33/574
Filed: 2008-07-28
Abstract: La présente invention concerne de nouveaux dérivés fluorescents de polyamines possédant un groupe benzoxadiazole, leur procédé de préparation et leur utilisation à titre d'outils de diagnostic permettant de mettre en évidence le système de transport des polyamines dans les cellules cancéreuses, et donc de sélectionner les patients porteurs de telles tumeur en vue d'adapter leur traitement. Ces dérivés correspondent à la formule (I) ou a un sel pharmaceutiquement acceptable de celui-ci, dans laquelle: R1 représente un ou plusieurs groupes NO2 en position 4 ou 6, ou bien un groupe SO2Ph, SO2NMe2, SO2NH2, SO3H, R2 représente un hydrogène, un alkyle en C1-6, un benzyl, un groupe perfluoroalkyle, les valeurs de a, b, c peuvent être de 2 à 5, indépendamment les unes des autres et représentent des enchaînements alkylènes séparant les groupes aminés, et les valeurs de d et e peuvent être indépendamment de 0 ou 1.
Patent CA-2694652-A1 (CA)
Inventor: STULEN FOSTER B
IPC: A61B17/32
Filed: 2008-07-24
Abstract: An end effector includes a first portion having a first specific acoustic impedance value, and a second portion having a second specific acoustic impedance value less than the first specific acoustic impedance value. The first portion includes a proximal end segment of th end effector and a distal end segment of the end effector, and the proximal end segment and the distal end segment are composed of first material. The second portion includes an insert segment of the end effector composed of a second material.  The insert segment is located between the proximal end segment and the distal end segment along the longitudinal axis of the end effector. The insert segment functions to bridge or fill the nodal energy gap.  A surgical instrument includes a transducer configured to produce vibrations along a longitudinal axis as a predetermined frequency.  An ultrasonic blade extends along the longitudinal axis coupled to the transducer.
Patent CA-2697798-A1 (CA)
Inventor: MAKHIJANI MAHESH
IPC: H04L12/56
Filed: 2008-09-17
Abstract: Techniques for sending and receiving signaling messages on shared and dedicated channels in a wireless communication system are described. A user equipment (UE) may receive a first signaling message on a shared channel during a first time period, receive a second signaling message on a dedicated channel during a second time period, and receive a third signaling message on the shared channel during a third time period. The UE may receive traffic data on the shared channel during all time periods. The UE may be handed over from a source Node B to a target Node B during the second time period. The UE may receive the first signaling message via the source Node B, receive the second signaling message via the source and target Node Bs, and receive the third signaling message via the target Node B.
Patent CA-2697924-A1 (CA)
Inventor: SELLEM ERIC
IPC: G06Q30/06
Filed: 2010-03-26
Abstract: The invention relates to the design of layouts for a room in which a user wishes to position elements figuring in a collection of catalogs. Prior art systems only allow incremental construction by making direct selections from one or more catalogs. The inventive system and procedure allow rapid, overall construction of several solutions satisfying a certain number of constraints determined by the room, the user or the distributor of the equipment to be positioned, as well as rules derived from experience in the field of the equipment concerned. The method is subdivided into the steps of spatial analysis, definition of layout templates, selection of candidates from the collection of catalogs and optimization of the positioning. The system permits simultaneous visualization in three dimensions of optimum solutions and the printing of two-dimensional assembly drawings. The procedure and the system are preferably applicable to kitchen layouts.
Patent CA-2699073-A1 (CA)
Inventor: BEVEC DORIAN
IPC: A61P35/00
Filed: 2008-09-09
Abstract: The present invention is directed to the use of the peptide compound Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser-OH as a therapeutic agent for the prophy-laxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, in-fectious diseases, lung diseases, heart and vascular diseases and metabolic diseases.  Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser-OH optionally together with at least one pharmaceutically acceptable carrier, cry-oprotectant, lyoprotectant, excipient and/or diluent.
Patent CA-2706080-A1 (CA)
Title: Diagnostic markers of wound infection
Inventor: PERCIVAL STEVEN LANE
IPC: G01N33/68
Filed: 2008-11-20
Abstract: A method of diagnosis or prediction of infection of a mammalian wound, said method comprising the step of detecting the presence of a cytokine selected from the group comprising procalcitonin, amino procalcitonin (N-ProCT), eotaxin, granulocyte macrophage colony stimulating factor (GM-CSF), interleukins IB monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1 alpha (MIP-1a), regulated upon activation normal T expressed and secreted (RANTES) in fluid taken from the wound. Also claimed is the device for use in the method.
Patent CA-2710739-A1 (CA)
Inventor: HOPKINS LARRY
IPC: F24F13/14
Filed: 2010-07-22
Abstract: A damper is provided. The damper includes a frame having a central opening through which air passes. A plurality of vanes are rotatably mounted within the frame. At least one of the vanes is oriented about a rotational axis that is offset at a non-orthogonal angle with respect to one of a horizontal and vertical axis.
Patent CA-2712734-A1 (CA)
Inventor: JOHNSTON BARRY WOODS
IPC: F02G1/04
Filed: 2009-01-23
Abstract: In a thermal system, low pressure fluid is returned to a source of high pressure fluid through a balance of internal pressures or forces that balances out the resistance to the flow of the working fluid being pumped from the low pressure to the high pressure.