baber/WOPTO huggingface dataset:
Patent MX-205459-A (MX)
Inventor: KLAVENESS JO
IPC: A61K49/00
Filed: 1985-05-30
Abstract: There are provided NMR contrast agents comprising water-soluble paramagnetic metal chelates, preferably of Cr(III), Fe(III) or Gd (III), wherein the chelating entity is an anilide group containing organic moiety, preferably a compound of formula Iwherein R<sup>1</sup> to R<sup>5</sup> may represent hydrogen or halogen atoms, optionally halogenated alkyl or alkyoxy groups or carboxyl groups. The agents are especially suitable for use in NMR imaging of the hepatobiliary system.
Patent NZ-194105-A (NZ)
Title: Synthesis of vincaminic acid derivatives
Inventor: ROSSEY G
IPC: C07D471/14
Filed: 1980-06-20
Abstract: Vincaminic acid derivatives of formula (A)    <IMAGE>  (A)  useful in treating cerebral insufficiency, are prepared by reacting 1-ethyl-2,3,4,6,7,12-hexahydroindolo[2,3-a]quinolizine with the 2,4-DNP hydrazone of ethyl or methyl bromopyruvate followed by (i) reduction of the C=N bond and (ii) simultaneous cyclization with removal of the ketone-protecting group in either order.
Patent NZ-200824-A (NZ)
Title: Repeater employs feedback equalisation in digital transmission on twisted pair
Inventor: CATCHPOLE R J
IPC: H04L25/03
Filed: 1982-06-02
Abstract: Feedback equalization is employed for digital repeaters of transmission systems having twisted-wire pairs, in order to reduce intersymbol interference while minimizing near-end crosstalk gain. Previously the incoming signal was selectively amplified at the higher frequencies in order to negate intersymbol interference, with subsequent near-end crosstalk gain. According to the present invention the intersymbol interference element of an incoming signal is cancelled, prior to amplification in an adder by a compensation signal derived from the output signal of a regenerator and a retimer. An output stage serves to amplify and shape the resultant signal to a form suitable for transmission. The compensation signal comprises the inverted output of a filtering and scaling network.
Patent NZ-201680-A (NZ)
Title: Wood preservative composition
Inventor: ALLEN W R SR
IPC: B05D3/12
Filed: 1982-08-24
Abstract: Wood is preserved with a water-based treating solution containing a halogenated phenol wood preservative such as pentachlorphenol, a phenolic resin prepolymer such as a phenol formaldehyde prepolymer, and a coupling or solubilizing agent for enhancing the water compatibility of the various ingredients. The treatment is carried out by exposing the wood, while submerged in the treating solution, so one or more cycles of reduced pressure (i.e. vacuum) and elevated pressure.
Patent NZ-203865-A (NZ)
Title: Double walled thermally insulated container with abutment ring between walls
Inventor: REMES R S
IPC: F17C13/08
Filed: 1983-04-13
Abstract: A container for the storage of liquids at temperatures that deviate widely from ambient temperature in which the container is formed with an outer vessel and an inner vessel supported by a neck tube from the outer vessel and which includes an annular ring member spanning the space between the outer and inner vessels adjacent their upper ends to stabilize the inner vessel within the outer vessel.
Patent NZ-206809-A (NZ)
Title: Heterocyclic compounds and pharmaceutical compositions
Inventor: FABRE J-L
IPC: A61K31/33
Filed: 1984-01-11
Abstract: Antithrombotics of the formula   <IMAGE>   in which A=S, SO or SO2, R3=H, alkyl or substituted or unsubstituted phenyl, X=O, S, NH or variously substituted nitrogen, p is 0 or 1 and y=H, NH2, or various substituted amines.
Patent NZ-224499-A (NZ)
Title: Process for enantiospecifically preparing (s)-2-ethylamino-1-(3-(trifluoromethyl)phenyl)propane: intermediates used therein
Inventor: FUGIER CLAUDE
IPC: C07C211/27
Filed: 1988-05-05
Abstract: New process for the enantiospecific preparation of (S)-2-ethylamino-1-(3-trifluoromethylphenyl)propane, characterised in that benzaldehyde is condensed with (S)-alaninol and that, after reduction, the product originating from the reaction is condensed with acetaldehyde to obtain (S)-N-benzyl-N-ethyl alaninol, which is subjected to the action of thionyl chloride to give, after neutralisation, (S)-2-(N-benzyl-N-ethylamino)-1-chloropropane, which is in its turn condensed with 3-trifluoromethylphenylmagnesium bromide to give (S)-2-(N-benzyl-N-ethylamino)-1-(3-trifluoromethylphenyl)- propane which, after debenzylation by hydrogenolysis, produces (S)-2-ethylamino-1-(3-trifluoromethylphenyl)propane.
Patent NZ-224928-A (NZ)
Title: N-(4-piperidinyl)bicyclic condensed 2-imidazolamine derivatives and pharmaceutical compositions
Inventor: JANSSENS FRANS EDWARD TORREMAN
IPC: C07D417/14
Filed: 1988-06-07
Abstract: Novel N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives of formula <CHEM> wherein: A<1>=A<2>-A<3>=A<4> is -CH=CH-CH=CH-, -N=CH-CH=CH-, -CH=N-CH=CH-, -CH=CH-N=CH or -CH=CH-CH=N-; R is hydrogen or C1-6alkyl; R<1> is furanyl substituted with C1-6alkyl, pyrazinyl, thiazolyl, or imidazolyl optionally substituted with C1-6alkyl; L is C3-6alkenyl optionally substituted with Ar<3>, or L is a radical of formula -Alk-R<3>, -Alk-O-R<4>, -Alk-N-(R<5>)-R<6>, -Alk-Z-C(=O)-R<7> or -CH2-CH(OH)-CH2-O-R<9>; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are anti-histaminic agents; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent NZ-228791-A (NZ)
Title: Scu-pa: single chain urokinase type plasminogen activator of low molecular weight
Inventor: BRANDAZZA ANNA
IPC: C12N15/55
Filed: 1989-04-18
Abstract: Low molecular weight derivatives of human prourokinase are provided which comprise at least the sequence from amino acid 163 to amino acid 411 of mature prourokinase in single chain configuration. In preferred cases, the sequences making up the kringle domain, the receptor binding domain or cell binding domain are missing. The derivatives may be made up into medicaments by admixture with a pharmaceutically acceptable carrier. Such medicaments show thrombolytic activity.
Patent NZ-236246-A (NZ)
Title: Soldering tip with internal heat sensor
Inventor: URBAN PAUL L
IPC: B23K3/03
Filed: 1990-11-28
Abstract: A soldering tip is provided with a sensor to sense soldering tip temperature during a soldering cycle. The sensor is embedded in the soldering tip and positioned immediately adjacent to the tip's working surface. The sensor location provides rapid response to changing conditions at the tips working surface. A microprocessor, responsive to the sensor, is provided to process the tip temperature data to control the power delivered to the heater which provides heat to the soldering tip. A visual and/or audio display also can be coupled to the processor. The microprocessor can be coupled to a further processor having long-term memory so that the collected data may be subsequently retrieved and displayed. <IMAGE>
Patent NZ-239425-A (NZ)
Title: Sulphonamide derivatives and pharmaceutical compositions
Inventor: HIROSHI YOSHINO
IPC: C07C311/44
Filed: 1991-08-16
Abstract: To provide new sulfonamide derivatives having an excellent antitumor activity and only a low toxicity and a process for producing them. Sulfonamide derivatives of the general formula (I): <CHEM> wherein preferably R<1> represents a lower alkoxy group, R<2>, R<3>, R<4>, R<5>, R<6> and R<7> may be the same or different from one another and each represent a hydrogen atom, halogen atom or lower alkyl group, A and B may be the same or different from each other and each represent =N- or =CH-, E represents an aromatic 6-membered cyclic group (which may have 1 or 2 nitrogen atoms in the ring) which may be substituted with 1 to 3 substituents which may be the same or different from one another with the proviso that a combination of R<1> which is a hydrogen atom, lower alkyl group, nitro group or amino group which may be protected, R<2> and R<3> which are each a hydrogen atom, A and B which are each =CH- and E which is a phenyl group which may be substituted with 1 to 3 substituents G which may be the same or different from one another is excluded, or pharmacologically acceptance salts of them.
Patent NZ-260261-A (NZ)
Title: Tamper evident closure; closure base with hinged lid connected thereto and tamper evident structure attached to either base or lid
Inventor: NEVERAS GEORGE J
IPC: B65D47/08
Filed: 1994-04-07
Abstract: Disclosed is a closure (1) for a container (2), the closure (1) having a lid (3) hinged to a base (5). The base (5) of the closure (1) has structure (15) for locking the closure (1) on a dispensing nozzle (7) of the container (2). The closure (1) has tamper evidence structure, to indicate whether the lid (3) and base (5) have been separated (that is, whether the closure has previously been opened). The tamper evidence structure includes a tear band (19); the closure (1) cannot be opened without removal of the tear band (19). The closure (1) is configured, and positioned relative to the dispensing nozzle (7), such that relatively little area of the closure (1) contacts the material dispensed from the container (2) as the material is dispensed, thereby reducing absorption of material components (e.g., flavors and/or oils of the material dispensed) by the closure. The top surface of the closure lid is configured such that the container (2) and closure (1) can be stably stood on end on the closure lid (3) when the lid (3) is in the closed position. The closure (1) can be held at least two positions on the dispensing nozzle (7), a first position where the closure (1) is locked on the dispensing nozzle (7) and a second position where the closure (1) is held on the dispensing nozzle (7) but not locked thereon. <IMAGE>
Patent NZ-260350-A (NZ)
Title: Phenoxyisobutyric acid derivatives, preparation and pharmaceutical compositions thereof
Inventor: REGNIER GILBERT
IPC: C07C319/20
Filed: 1994-04-19
Abstract: The substituted phenoxyisobutyric acids and their esters of formula I: <IMAGE>  in which:     - X represents an oxygen atom, a sulphur atom or a single bond; - A represents a single bond or a hydrocarbon radical containing from 1 to 9 carbon atoms in a straight or branched chain optionally containing a double bond, a cyclopropyl radical, an oxygen atom or a carbonyl radical, or optionally substituted by a halogen atom or a hydroxyl radical; - R represents a hydrogen atom or an alkyl radical containing from 1 to 6 carbon atoms in a straight or branched chain optionally substituted by one or two hydroxyl radicals;   - R1 and R3:     . each simultaneously represent a hydrogen atom, or . together form a bridge (CH2)n in which n takes the values 1 or 2, or   . R1 represents:     . a methyl radical, or . a single bond which forms a double bond with the group A when the latter is a hydrocarbon radical, and   . in each of these cases, R3 simultaneously represents a hydrogen atom;   - R2 and R6, which are identical or different, each represent a hydrogen atom or a methyl radical; - R4 and R5, which are identical or different, each represent an alkyl radical containing from 1 to 6 carbon atoms in a straight or branched chain; - R7 represents a hydrogen atom or a labile protective group such as, for example, a CH3CO-, C2H5O-CH2- or benzyl radical; and - Z represents a hydrogen or halogen atom or an alkyl or alkoxy radical each containing from 1 to 5 carbon atoms in a straight or branched chain; and, when they exist, the corresponding enantiomers and diastereoisomers, as well as the physiologically tolerable salts of the compounds I with appropriate bases, can be used in therapeutics.d
Patent NZ-266423-A (NZ)
Title: Evaluation of bone cell activity, apparatus therefor
Inventor: DAVIES JOHN E
IPC: C12M3/04
Filed: 1994-05-18
Abstract: PCT No. PCT/CA94/00285 Sec. 371 Date Jul. 12, 1995 Sec. 102(e) Date Jul. 12, 1995 PCT Filed May 18, 1994 PCT Pub. No. WO94/26872 PCT Pub. Date Nov. 24, 1994A calcium phosphate based thin film on which bone cells may be cultured to permit evaluation of bone cell functional properties comprises calcium phosphate entities which provide for varying degrees of resorption of the calcium phosphate entities in evaluating the functional properties. The film is sufficiently thin that resorption of the entities can be detected. Such film, as applied to a support, is a very useful analytical component for evaluating such bone cell functional characteristics. An analytical device, which may be used in an analytical kit, can be provided having a plurality of wells with the devices located at the bottom thereof. A process is provided for making the film and especially the film which has a combination of calcium hydroxyapatite with tricalcium phosphate.
Patent NZ-281204-A (NZ)
Title: Ice confection coating wherein confection is first coated with a precoating of couverture and then with a couverture composition
Inventor: RAYET JASPAL
IPC: A23G9/24
Filed: 1995-02-03
Abstract: An ice confection having a couverture layer is first coated with a precoating of couverture and then again with a couverture composition to complete the layer.
Patent NZ-295506-A (NZ)
Title: Caulking gun cartridge, backwall has smaller diameter than body to prevent afterflow
Inventor: VANMOOR ARTHUR
IPC: B65D88/54
Filed: 1995-09-13
Abstract: A caulking gun and cartridge combination is provided with afterflow prevention. The cartridge has a tubular body (8), a forward dispensing opening (9) at a forward end of the tubular body, and a backwall (11, 12) movably disposed within the tubular body (8). The caulking gun has a trough (1) for receiving the cartridge, and a piston (4) movable parallel to the trough (1). A trigger handle (23) is used for pushing the backwall (11) forward within the tubular body and causing a reduction of volume within the chamber (13) in the cartridge. The backwall slides substantially in a contact-less manner within the tubular body, preferebly by way of a reduced diameter (OD) of the backwall (11) relative the inner diameter (ID) of the tubular body (8), so that it is pushed backwardly when the body retracts radially after actuation. Alternatively, the cartridge body may be prevented from expanding or may even be actively squeezed so that afterflow caused by the volume reduction of the relaxing tube body is safely prevented.
Patent NZ-299262-A (NZ)
Title: Medicament inhaler has a metering device with an indexing device and dosing space
Inventor: BRAITHWAITE PHILIP WILSON
IPC: G01F11/12
Filed: 1993-02-18
Abstract: The invention provides an inhaler 140 for delivering a substance in a finely divided form. The inhaler 140 comprising an air intake and an inhalation passage 144 communicating with the air intake. A receptacle 145 in combination with a metering device having first and second end elements sealing against the inner walls of the receptacle so as to define an intermediate dosing space loaded with a desired volumetric dose of the substance is provided. The relative dimensions of the metering device and receptacle 145 are such that the device has a tendency to remain in the receptacle unless actively urged out of it. Indexing means 146 operate to move the receptacle into a position in or adjacent the inhalation passage and means are provided for urging the metering device at least partially out of the receptacle so as to release the dose of substance contained in the receptacle into the inhalation passage when the receptacle occupies its position in or adjacent the inhalation passage 144. <IMAGE>
Patent NZ-332233-A (NZ)
Title: Denaturants for sympathomimetic amine salts to make these compounds less suitable as starting materials for the production of illegal drugs
Inventor: NICHOLS W MICHAEL
IPC: A61K47/20
Filed: 1997-04-01
Abstract: The present invention is directed to the addition of one or more pharmaceutically and biologically acceptable denaturants to sympathomimetic amine salt-containing pharmaceutical products to make these products less suitable as starting materials for the production of illegal drugs. In one preferred embodiment, the denaturant(s) and the sympathomimetic amine salt exhibit similar chemical and/or physical properties, so that purification of sympathomimetic amine by conventional extraction techniques is rendered difficult or essentially infeasible. In another preferred embodiment, the denaturant physically interferes with the extraction of the sympathomimetic amine salt from the pharmaceutical products i.e., emulsifies and/or alters the viscosity of the pharmaceutical products in solution). Because the separation of denaturant(s) from the sympathomimetic amine salts is rendered impracticable, attempts to isolate the sympathomimetic amine salts from compositions of the invention are unsuccessful or results in preparations that are converted into adulterated illegal drug products. The present invention is directed to denaturant-containing sympathomimetic amine products and to methods for their preparation. The denaturant-containing sympathomimetic amine products are used for known indications treated by sympathomimetic amines.
Patent NZ-335827-A (NZ)
Title: Strengthening flat glass by edge coating
Inventor: PAPANU VICTOR DENNIS
IPC: C03C17/28
Filed: 1998-09-01
Abstract: A method is described for strengthening or restoring strength to a flat brittle oxide substrate (12) which includes the steps of coating the edges of the brittle oxide substrate (12) with a strengthening composition without coating a significant portion of the major flat surfaces of the substrate (12). The strengthened brittle oxide substrate (12), such as glass, and a window containing as a window pane the edge strengthened glass (12) are also provided.
Patent NZ-336786-A (NZ)
Title: Aqueous dispersions of hydrophobic material comprising a dispersant comprising an anionic compound and a cationic compound, at least one of which is a polyelectrolyte
Inventor: HALLSTROM HANS
IPC: D21H/
Filed: 1998-02-03
Abstract: The invention relates to an aqueous dispersion containing a dispersant and a disperse phase containing a hydrophobic material, the dispersant comprising an anionic compound having a molecular weight less than 50,000 and being selected from carbon-containing compounds and silicon-containing compounds, and a cationic organic compound having a molecular weight less than 50,000. The invention further relates to the preparation and use of the dispersion in the production of paper. The invention also relates to a substantially water-free composition containing a hydrophobic material, an anionic compound having a molecular weight less than 50,000 and being selected from carbon-containing compounds and silicon-containing compounds, and a cationic organic compound having a molecular weight less than 50,000, as well as its use in the preparation of an aqueous dispersion.
Patent NZ-337601-A (NZ)
Title: Gamma-1 and gamma-3 anti-human CD23 monoclonal antibodies and use thereof as therapeutics by inhibiting IgE expression
Inventor: REFF MITCHELL E
IPC: C07K/
Filed: 1998-02-17
Abstract: An anti-human CD23 monoclonal antibody comprising a constant region that binds to human Fc gamma receptors and inhibits IgE expression.   The monoclonal antibody has a binding affinity of at least 100nM.  Also claimed is a pharmaceutical composition containing said CD23 antibody, and the use of the antibody for treating and preventing a disease condition where the inhibition of IgE is therapeutically or prophylactically beneficial.
Patent NZ-508090-A (NZ)
Title: Manufacture of shaped bodies from a mat containing fibres and particles of cellulose or lignocellulose where the mat is pressed while supplying heat and pressure
Inventor: IREDI HANS-JOACHIM
IPC: B27N3/18
Filed: 1999-04-30
Abstract: A method of manufacturing shaped bodies, in particular fibreboard, chipboard or like boards is disclosed, in which fibres admixed with a binder, particles containing cellulose admixed with a binder, or particles containing lignocellulose admixed with a binder, or particles containing lignocellulose admixed with a binder are scattered to form a mat and preheated before the mat is pressed to the shaped body while supplying heat and pressure, characterized in that the preheating of the mat consisting of the pre-compacted or pre-presses fibres or particles takes place by the supply of thermal energy from the interior of the mat outwardly to the surface of the mat.  An apparatus to carry out the method is also disclosed.
Patent NZ-509391-A (NZ)
Title: Oxacarbazepine film-coated tablets further comprising a hydrophobic permeable outer coating containing iron oxide from 0.3 to 0.9 mg per tablet
Inventor: SCHLUTERMANN BURKHARD
IPC: A61K9/28
Filed: 1998-02-12
Abstract: A film coated tablet containing up to 73 weight percent oxcarbazepine based on the total weight of the tablet. A process for making a tablet thereof is also described.
Patent NZ-513870-A (NZ)
Title: Separable Kitchen tongs with a cutting edge and    other food processing utilities
Inventor: BARON CRAIG A
IPC: A47G21/10
Filed: 2001-08-29
Abstract: Multi-function culinary tongs are provided, comprising two elongate tong members (10, 11) hingedly connected.  Each tong member has an inwardly facing open channel section for handling, and a food-grasping end (13).  A removable pin (12) enables the tongs to be separated from one another.  The food-grasping end (13) may have a plurality of features to increase the utility of the tongs, selected from a bladed region (17), a serrated cutting or scraping region (19), a flattened screw-driver end piece (21), and a bottle cap remover (22).  A zester (23) may be formed on the end of each tong member adjacent to the hinge connection.
Patent NZ-514793-A (NZ)
Title: Fluid valve
Inventor: ESCHE JOHN
IPC: B65H75/48
Filed: 2000-04-13
Abstract: A three position valve (10) suitable for use in a trigger nozzle assembly (12) is disclosed which is suitable for use in kitchen utensil rinsing areas has a valve housing with a bore, a fluid inlet (52) and a fluid outlet (53). A biased slidable member (56) is positioned in the bore and provides for fluid flow between the fluid inlet (52) and outlet (53) when the valve (10) is in a first position. High flow and stop flow positions are also provided upon compression of the trigger (14). The valve (10) is employed in conjunction with a combined spray and aerator head (16), as well as a hose take-up assembly (31).
Patent NZ-516917-A (NZ)
Title: Hexahydropyrrolo[1,2-C]pyrimidines as antiviral, antifungal and/or antitumor agents
Inventor: OVERMAN LARRY A
IPC: A61P31/12
Filed: 2000-06-30
Abstract: A compound of formula (I), wherein: R is H, carboxylic acid protecting group, ù-alkoxycarboxylic acid or an ù-alkoxycarboxylic acid ester, and X is any pharmaceutical acceptable counter-ion.
Patent NZ-521576-A (NZ)
Title: Novel cyclic amide derivatives
Inventor: YAMABE HARUKO
IPC: A61P1/06
Filed: 2001-02-26
Abstract: Describes compounds represented by the formula (I) or a salt thereof, or a hydrate or a solvate thereof: wherein: X represents alkyl, cycloalkyl-substituted alkyl, aryl-substituted alkyl, aryl-substituted alkenyl, aryl-substituted alkynyl, monocyclic or polycyclic cycloalkyl which may be substituted with an alkyl, aryl, heterocyclic group, or substituted or unsubstituted amino group; Q represents a group represented by -CH2-, -CO-, -O-, -S-, -CH(OR7)-, -C(=CH2)- or -(=NR8)- wherein R represents a hydrogen, alkyl, hydroxyalkyl, or an acyl group, and R8 represents a hydroxyl, alkoxyl, aralkyloxy, acyloxy, acylamino, or an alkoxycarbonyl amino group; n represents an integer of from 0 to 5; R1 and R2 each independently represent a hydrogen atom or an alkyl group, or R1 and R2 combine to form an alkylene group; B represents either of the groups defined in formula (II): Further describes the use of the compounds of formula (I) in the manufacture of a medicament, which is used for a disease that can be therapeutically and/or preventatively treated by nerve controlling function of a sigma ligand, in a patient in need thereof.