Patent SG-11201806951T-A (SG)
Title: Peptides, combination of peptides, and cell based medicaments for use in immunotherapy against urinary bladder cancer and other cancers
Inventor: MAHR ANDREA
IPC: C07K14/47
Filed: 2017-02-28
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 HO 11111 011010 111111111 11111111 10111110H III International Bureau .. .... ..Yejd ..... ....!;,,,' (10) International Publication Number (43) International Publication Date WO 2017/148888 Al 8 September 2017 (08.09.2017) WIP0 I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 39/00 (2006.01) CO7K 7/06 (2006.01) kind of national protection available): AE, AG, AL, AM, C07K 14/47 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, (21) International Application Number: DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, PCT/EP2017/054559 HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (22) International Filing Date: KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, 28 February 2017 (28.02.2017) MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (25) Filing Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (26) Publication Language: English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 1603568.5 1 March 2016 (01.03.2016) GB (84) Designated States (unless otherwise indicated, for every 62/302,010 1 March 2016 (01.03.2016) US kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (71) Applicant: IMMATICS BIOTECHNOLOGIES GMBH TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, [DE/DE]; Paul-Ehrlich-Strasse 15, 72076 Tuebingen (DE). TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (72) Inventors: MAHR, Andrea; Kirschenweg 22, 72076 DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, Tuebingen (DE). WEINSCHENK, Toni; Im Morgenrain LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, 15, 73773 Aichwald (DE). SONG, Colette; Wil- — li-Baumeister-Weg 21, 73760 Ostfildern (DE). SCHOOR, GW, KM, ML, MR, NE, SN, TD, TG). Oliver; Eichhaldenstrasse 19, 72074 Tuebingen (DE). Published: FRITSCHE, Jens; Laerchenweg 11, 72144 Dusslingen — with international search report (Art. 21(3)) (DE). SINGH, Harpreet; 2215 Dryden Rd, TX 77030 = — before the expiration of the time limit for amending the Houston (DE). claims and to be republished in the event of receipt of (74) Agent: BOEHMERT & BOEHMERT; Jan B. KRAUSS, = amendments (Rule 48.2(h)) Pettenkoferstrasse 22, 80336 Munich (DE). — listing description 5.2(a)) with sequence part of (Rule = = = = = = = = Il GC GC GC GC si. (54) Title: PEPTIDES, COMBINATION OF PEPTIDES, AND CELL BASED MEDICAMENTS FOR USE IN IMMUNOTHER- APY AGAINST URINARY BLADDER CANCER AND OTHER CANCERS L . ' (57) : The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In ::::) particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor- associ - ei ated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active phar - 0 maceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and ,-t transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.