baber/WOPTO huggingface dataset:
Patent WO-2019186570-A1 (WO)
Title: Methods of disrupting a biofilm and/or preventing formation of same
Inventor: KOLODKIN-GAL ILANA
IPC: A61P31/04
Filed: 2019-03-28
Abstract: Methods of disrupting a biofilm and/or preventing formation of a biofilm are provided. Accordingly there is provided a method of reducing or preventing formation of a biofilm and/or disrupting a biofilm comprising contacting a biofilm-producing microorganism with a carbonic anhydrase inhibitor; a urease inhibitor; a Ca2+ ATPase inhibitor; a tip activator; and/or a myoinositol catabolism pathway activator. Also provided are articles of manufacture and methods of treating a medical condition in which disrupting a biofilm and/or preventing formation of same is beneficial and methods of predicting or increasing sensitivity to an anti-microbial agent.
Patent WO-2020065649-A1 (WO)
Inventor: BEN NUN YARON
IPC: F28D20/02
Filed: 2019-09-25
Abstract: A thermal-storage container used in thermal systems to exchange heat by fluid flow though phase-changing material disposed inside the thermal-storage container, including a thermal-storage container housing, a fluid inlet and a fluid outlet, and one or more capsules containing the phase- change material, and defining a plurality of passages configured to direct the flow of the fluid at different portions inside the housing, wherein an actual fluid flow length from the fluid inlet to the fluid outlet is longer than a direct length measured between the fluid inlet and the fluid outlet through all sections through which the fluid flows. Related apparatus and methods are also described.
Patent WO-2021079362-A1 (WO)
Title: A method for imprinting micropatterns on a substrate of an organic polymer
Inventor: SCHVARTZMAN MARK
IPC: B29C33/40
Filed: 2020-10-15
Abstract: A method for nanoimprinting a pattern on an organic polymer substrate, comprising: (a)preparing a soft operational mold, the operational mold comprising a pattern to be replicated to the substrate; (b) soaking the operational mold in a solvent to produce diffusion of solvent to the mold; (c) removing the operational mold from the solvent, and placing it on a surface of the organic polymer substrate to form a structure, and simultaneously (i) heating the structure to a temperature T<Tg, where Tg is the glass transition temperature of the organic polymer; and (ii) applying controlled pressure in a range of 20 - 300 psi on the mold to effect a penetration into the surface of the organic polymer substrate, thereby to replicate the pattern of the mold to the surface of the substrate; and (d) separating the operational mold from the patterned substrate.
Patent WO-2021084540-A1 (WO)
Title: Inhibitors of mmej pathway for prevention and treatment of pre-myeloid and myeloid malignancies
Inventor: SHLUSH LIRAN
IPC: A61P35/00
Filed: 2020-10-29
Abstract: An inhibitor of a component of the Microhomology Mediated End Joining (MMEJ) pathway is provided for use in treating or prevention of a pre-myeloid or myeloid malignancy in a subject in need thereof, wherein the pre-myeloid or myeloid malignancy is not chronic myeloid leukemia (CML).
Patent WO-2022149125-A1 (WO)
Title: Methods and compositions for melanin synthesis
Inventor: BARUCH LESHEM AVIGAIL-ELAH
IPC: A61K31/404
Filed: 2022-01-02
Abstract: The invention relates to a composition comprising a polymer - based droplet, wherein the polymer - based droplet comprises one or more of melanin, a tyrosine substrate with a cleavable protecting group on the side chain, tyrosine, tyrosinase and any combination thereof. The composition further relates to a method of synthesizing melanin comprising the steps of: obtaining a polymer - based droplet containing a tyrosine substrate with a cleavable protecting group on the side chain (protected tyrosine) or a polymer - based droplet containing tyrosine (unprotected); wherein the tyrosine is oxidized by tyrosinase and polymerizes so as to obtain melanin.
Patent WO-2022254436-A1 (WO)
Title: Closed-loop steering of a medical instrument toward a moving target
Inventor: SHACHAR NIR
IPC: A61B17/34
Filed: 2022-06-01
Abstract: Provided are systems, devices and methods for generating and/or utilizing data- analysis model(s) for updating in real-time a trajectory for inserting a medical instrument toward a target in a body of a subject, based on the predicted movement of the target, and steering the instrument toward the moving target according to the real-time updated trajectory.
Patent WO-2012017452-A1 (WO)
Inventor: LAXMAN BOROLE YOGESH
IPC: C07D301/12
Filed: 2011-08-03
Abstract: Titanosilicate catalyst is used in the oxidation reactions such as allylchloride epoxidation, phenol hydroxylation, Cyclohexanone ammoximation. During the reaction the catalyst is deactivated which further decrease in the efficiency of the oxidation reactions. The present invention provides a method for an efficient regeneration of catalyst titanosilicate catalyst at low temperature below 100°C using a gaseous mixture containing ozone.without isolating the catalyst from the reactor system.
Patent WO-2013054337-A1 (WO)
Title: Extended release pharmaceutical compositions of fesoterodine
Inventor: ROY SUNILENDU BHUSHAN
IPC: A61K31/222
Filed: 2012-07-04
Abstract: A stable extended release. pharmaceutical composition is disclosed. The composition comprises particles of fesoterodine or salts thereof, one or more rate controlling polymers and one or more pharmaceutically acceptable excipients, wherein at least 90% of the total amount of particles of fesoterodine or salts thereof by volume (D 90 ) are having size greater than about 200 microns.
Patent WO-2013132516-A1 (WO)
Title: Pneu sans chambre à air à chambres multiples et son procédé de fabrication
Inventor: SATPATHY SMITIPARNA
IPC: B29D30/06
Filed: 2013-03-04
Abstract: L'invention concerne un pneu sans chambre à air à chambres multiples ou une chambre à air et le procédé de fabrication de ceux-ci pour des véhicules. Ledit pneu ou ladite chambre comprend une chambre principale près de la jante pour maintenir/contenir l'air/le fluide sous pression; au moins une chambre prise en sandwich entre ladite chambre principale et la surface interne du pneu, ladite ou lesdites chambres prises en sandwich ayant une valve d'admission unidirectionnelle indépendante pour le produit d'étanchéité ou le fluide/l'air sous pression, selon le cas; ladite ou lesdites chambres prises en sandwich sont formées et jointes à l'état vert à ladite chambre à air verte ou ledit pneu sans chambre à air vert de manière à atteindre des propriétés mécaniques après vulcanisation. Même une chambre indépendante peut être prise en sandwich entre ladite chambre principale et la surface interne du pneu.
Patent WO-2018104966-A1 (WO)
Title: Système de gestion de batterie rechargeable,
Inventor: KUMAR MAINI CHETAN
IPC: G06Q10/00
Filed: 2017-12-07
Abstract: ET BATTERIE RECHARGEABLE Selon certains modes de réalisation, la présente invention concerne des batteries rechargeables et, en particulier, des batteries rechargeables interchangeables. Selon certains modes de réalisation, la présente invention concerne un module de batterie modulaire standardisé, ce module de batterie pouvant servir à une pluralité d'applications et étant constitué d'un système d'assemblage et de communication de paramètres liés à l'application et à la batterie.
Patent WO-2020152696-A1 (WO)
Title: Methods and apparatuses for tempering organic products
Inventor: ALVA JUNIA
IPC: A23B4/07
Filed: 2019-02-05
Abstract: The invention relates to a method and apparatus of tempering an organic product in an enclosed structure using a liquid maintained at a predefined temperature. The method includes, introducing the organic product through an access means of the enclosed structure into the liquid, circulating the liquid from the enclosed structure through a heating unit and back into the enclosed structure to increase a temperature of the liquid up to a predefined temperature, and supplying carbon dioxide gas into the enclosed structure for a predefined time period based on a temperature of the liquid in the enclosed structure. The organic product is removed through the access means of the enclosed structure when a core temperature of the organic product reaches the predefined temperature. The circulation of the liquid and the supply of carbon dioxide gas is ceased during the removing of the organic product.
Patent WO-2020053897-A1 (WO)
Title: Poliovirus receptor (pvr/cd155) knockout cells derived from rd (human rhabdomyosarcoma) cell line by crispr.
Inventor: NANDI S S
IPC: A61K39/13
Filed: 2019-09-13
Abstract: The present invention provides a modified polio virus receptor (PVR/CD155) gene. Said gene comprises one or more mutations in exons selected from exons 2, 3 and 4 of poliovirus receptor (PVR/CD155) gene having SEQ ID No.1. More specifically, the present invention provides cell lines comprising said modified gene and method of producing the same using clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein 9 (CRISPR-Cas9) system. The said cell line is refractory (non-permissive) to poliovirus and susceptible to most enteroviruses and many other human viruses. Further, use of said cell line is research, diagnostic and therapy.
Patent WO-2006008777-A1 (WO)
Title: Dispositif permettant d'exciter un electroaimant, notamment pour actionner des pompes
Inventor: LIVOTI STEFANO
IPC: H02P25/02
Filed: 2005-07-20
Abstract: L'invention concerne un dispositif permettant d'exciter un électroaimant (4), destiné notamment à actionner des pompes et comprenant une enroulement primaire (3) et un élément mobile (9). Ce dispositif, qui comprend un moyen électronique de commutation d'alimentation (S1, S2), est caractérisé en ce qu'il comprend une unité logique de commande (6) permettant de commander le moyen électronique de commutation d'alimentation (S1, S2) et de détecter la valeur du courant d'excitation, le bloc d'alimentation de l'unité logique de commande (6) étant pourvu d'un shunt correspondant (PP) de l'enroulement primaire (3), l'unité logique de commande (6) commandant le moyen électronique de commutation d'alimentation (S1, S2) en fonction de la valeur détectée du courant d'excitation, de façon à faire fonctionner l'électroaimant (4) comme un autotransformateur afin de suffisamment alimenter l'unité logique de commande (6) en électricité et de laisser ainsi la fonction d'attraction de l'élément mobile (9) sensiblement inchangée. L'invention concerne également l'électroaimant excité correspondant et le procédé associé permettant d'exciter l'électroaimant.
Patent WO-2011010336-A1 (WO)
Title: Operating process for the production of an insole for footwear and insole thus obtained
Inventor: GISMONDI ANDREA
IPC: A43D8/34
Filed: 2010-07-21
Abstract: Machining process for the manufacture of an insole for footwear, having a tape (2) at the bottom face (B) of the insole (1) and around < the entire periphery thereof, except only for that horseshoe arch that surrounds the heel of the shoe if desired, the outer edge (2a) of said tape being attached to and aligned with the edge (1a) of the insole (1) so that the inner edge (2b) of said tape (2) is free to be folded and detached from the bottom face (B) of the insole (1), said process including the following operational steps: cutting the insole (1) along a plane parallel thereto so as to open the insole from the tip to the plantar arch, dividing it into a top half-insole (1c) and a bottom half-insole (1d); fixing said tape (2) beneath the bottom half-insole (1d) so that the outer edge (2a) of said tape (2) is fixed to and aligned with the edge (1e) of the bottom half-sole (1d), while the inner edge (2b) of the tape (2) is free to be folded and detached from the bottom half-insole (1d); inserting a padding layer (5) between the two half-insoles (1c and 1d), which are then laid down and glued peripherally one on top of the other, to form a sandwich structure together with the intermediate layer (5).
Patent WO-2012090233-A1 (WO)
Title: Labelling group
Inventor: CARMICHAEL JAMES
IPC: B65C9/18
Filed: 2010-12-30
Abstract: There is disclosed a labelling group (5) for applying labels (2) to relative articles, comprising a first support structure (16); a second support structure (17); first support structure (16) supporting either an unwinding element (10c) for unwinding a strip (10b) of labels (2) along an advancing path (Q) or a cutter (11) which may be fed with a strip (10b) of labels and is adapted, in use, to cut a single label (2) from strip (10b); a gluing element (12) which is supported by second support structure (17) and applies, in use, glue onto cut label (2); the labelling group (5) may be selectively arranged into: a first configuration in which first support structure (16) is fixed to second support structure (17); or in a second configuration in which at least one of first and second support structure (16, 17) may rotate relative to the other one of first and second support structure (16, 17).
Patent WO-2014181367-A1 (WO)
Title: Procédé et système pertinent de conversion en énergie électrique d'une énergie mécanique à partir d'un générateur actionné par une turbine
Inventor: VITALE GIANPAOLO
IPC: F03D7/04
Filed: 2014-05-05
Abstract: L'invention concerne un procédé permettant de convertir en énergie électrique une énergie mécanique provenant d'un générateur (2) actionné par une turbine (T) ; l'énergie électrique devant être entrée dans un réseau électrique (R). Le procédé comprend les étapes suivantes : (A) l'apport d'un convertisseur (3) électronique de puissance, pouvant être raccordé à l'entrée du générateur (2) et à la sortie du réseau électrique (R) ; (B) l'apport d'une sortie d'énergie électrique  ( P e/ ) du générateur (2) au convertisseur (3) électronique de puissance ; (C) l'adaptation de l'énergie électrique  ( P e/ ) à l'aide du convertisseur (3) électronique de puissance pour entrer l'énergie électrique  ( P e/ ) au réseau électrique (R), grâce aux étapes secondaires suivantes : (CI) le calcul de la vitesse ( ωr ) de rotation de la turbine (T) ; (C2) le calcul de la vitesse (V) du vent qui déplace la turbine (T) ; (C3) le calcul de la vitesse (   ω Tref ) de rotation de référence, correspondant au point maximum de l'entrée d'énergie dans le réseau (R) électrique, à l'aide d'un algorithme de suivi du point d'énergie maximum (MPPT) ; le procédé étant caractérisé en ce que l'étape secondaire (CI) est mise en place par un algorithme qui réalise un encodeur virtuel et l'étape secondaire (C2) est mise en place par l'entraînement d'un réseau neuronal qui met en œuvre un anémomètre virtuel. De plus, l'invention concerne un système qui met en œuvre ce procédé.
Patent WO-2018047204-A1 (WO)
Title: Système multimédia avec interface homme-machine pour activité de barman avancée
Inventor: PASCAZIO ANTONELLO
IPC: G09B19/00
Filed: 2016-09-08
Abstract: L'invention concerne un système multimédia permettant de former des barmen ou de les aider dans leur travail, qui est parfaitement intégré dans le poste de travail d'un bar. Le système est composé d'un ordinateur personnel avec un écran, d'un écouteur avec la technologie Bluetooth®, ainsi que d'un ordinateur de poche et d'un système mis en œuvre ad hoc qui est équipé d'une intelligence artificielle indépendante basée sur des algorithmes génétiques. Ce système considère comme entrée une commande composée de différentes boissons choisies par l'utilisateur ou générées par le logiciel à des fins de formation ou fournies par l'ordinateur de poche pour l'aide au travail. Le logiciel élabore la commande, puis cette élaboration est affichée à l'écran avec les opérations que le barman doit effectuer. L'écouteur reproduit également les opérations. Après cette étape, l'interaction entre le système et l'utilisateur s'effectue exclusivement à l'aide de la voix jusqu'à la fin de la préparation. L'invention permet d'améliorer radicalement la vitesse, l'efficacité, la précision et le mode de raisonnement du barman tout en réduisant sensiblement le temps de préparation d'une boisson.
Patent IT-BO20020160-A1 (IT)
IPC: B01F13/10
Filed: 2002-03-28
Abstract: A machine structure, in particular for the processing of fluid products, including a loadbearing frame with vertical uprights ( 12 ) connected by two horizontal plates ( 14, 15 ) at a distance from each other. Between the uprights are located one or more removable covering panels ( 13 ) which cover the zone housing the machine components. The machine structure is strong but light, not very bulky and easy to assemble even by non-specialist personnel.
Patent IT-BO20050478-A1 (IT)
Inventor: GIORNELLI PIETRO
Filed: 2005-07-18
Abstract: A multiple package (1), comprising a plurality of containers (2), each associated with at least one other container and substantially shaped complementarily with respect to each other, so as to constitute, in a closed configuration in which they are substantially mutually adjacent in a predefined ordered manner, a solid which has a minimal space occupation.
Patent IT-MI20001005-A1 (IT)
Inventor: DE NICHILO GIORGIO
IPC: B29C51/26
Filed: 2000-05-08
Abstract: Extensible gripper (5) for clamping plastics material plates (4) on thermoforming apparatus for on-line thermoforming the plastics material plates (4), in which supporting assemblies support slidably with respect to a central body (7), sliding blocks (22,24) which can be driven to project from the side of the central body (7), thereby providing the gripper (5) with a length which can amount to twice the length of the central body (7), while providing the required gripping mechanical force on the head portions of the plastics material plates (4). <IMAGE>
Patent IT-MI20052514-A1 (IT)
Inventor: GALEOTTI ARMANDO
Filed: 2005-12-29
Abstract: Process for the production of vinyl-aromatic monomers which comprises: a) feeding an aromatic stream and an olefinic stream to alkylation; b) feeding the reaction product coming from the alkylation section to a first separation section; c) recovering the mono-alkylated aromatic hydrocarbon from the first separation section; d) feeding the mono-alkylated aromatic product to a dehydrogenation section; e) cooling and condensing the reaction gases in the shell of one or more heat exchangers; f) feeding the reaction product coming from the dehydrogenation section to a second separation section; g) recovering the stream of vinyl-aromatic monomer.
Patent IT-MI20082226-A1 (IT)
Inventor: GUL ABID AKHTAR
Filed: 2008-12-16
Abstract: The device (1) has a dust collector, a cover (3), and an obstacle recognition system (5) comprising a rocker-like feeler element (6) that is arranged in a protruding area. Deflection of the feeler element is used for recognizing an obstacle, and a sensor sensorily detects foot-side movement of the feeler element. The feeler element is fastened to the collecting device at a foot side, and the movement considered from a protruding end of the feeler element is partly detected beyond a joint. A leaf spring is connected with the feeler element in a region of a T-arm (9).
Patent IT-RM20020453-A1 (IT)
Inventor: ARMELLIN ALBERTO
IPC: B05C11/08
Filed: 2002-09-10
Abstract: A process and relating plant for applying protective coats of paint to containers, especially plastic bottles. The process involves gripping the bottles by means of rotating gripping devices fastened to a conveyor chain, and conveying said bottles to all the different stations involved in the process: coating, drying, and curing. Centrifugation is used to remove any excess coating from the external surface of the bottles, keeping the bottles fastened to the same conveyor chain.
Patent IT-TO20010546-A1 (IT)
Inventor: COTTALASSO MAURIZIO
IPC: G01S17/933
Filed: 2001-06-06
Abstract: An obstacle advisory system determines the likely trajectory 16 of a vehicle and possible waypoints 17, 18 and 19 at predetermined intervals  DELTA  chi  along the trajectory 16. The system determines if the trajectory 16 is straight or curved and dependent on this determination uses an associated equation to determine the distance  DELTA  chi  between waypoints 17, 18 and 19 along the likely trajectory 16. <??>For a straight trajectory the interval  DELTA  chi  between waypoints 17, 18 and 19 is calculated by: <DF> DELTA x = 2<SQRT>R<2> - y<2></SQRT> </DF> where R is the radius of a spherical region 20, 21 or 22 around the vehicle and y is the radius of a notional minimum sphere that encloses the vehicle. <??>Then analysis determines whether or not a region 20, 21 or 22 centred around its respective possible waypoint 17, 18 and 19 includes an obstacle. If the region 20, 21 and 22 does not include a obstacle then the system can disregard the volume enclosed by the region 20, 21 or 22 from further analysis thereby saving processing. Alternatively, the system subdivides the region into smaller regions for further analysis and determination as to whether or not the region still includes the obstacle. <??>The results are displayed to an operator of the vehicle. Calculation of waypoints for a likely curved trajectory is also disclosed. <IMAGE>
Patent WO-2022180654-A1 (WO)
Inventor: MADANAT SAHAR
IPC: C08K13/04
Filed: 2022-02-28
Abstract: The present disclosure provides a material composition comprising essentially of plant fibers, at least at least one anti-mold agent, and at least one anti-bacterial agent in order to develop a valuable and sustainable material which can be utilized in various industrial applications, and methods of preparation thereof.
Patent JP-WO2002100868-A1 (JP)
Title: リン酸エステルの製造方法
IPC: C07F9/14
Filed: 2002-04-25
Abstract: 工程（１）：ナフトールにオキシ塩化リンを１：１．３以上のモル比で、金属ハロゲン化物の存在下で反応させ、未反応のオキシ塩化リンを除去した後、工程（２）：工程（１）の反応生成物とフェノールとを１：１〜１．５のモル比（但し、反応生成物中の塩素原子に対するフェノールのモル比）で反応させ、副生した塩化水素を除去し、一般式（Ｉ）：（式中、ｎは１または２を示す）で表されるリン酸エステルを得ることからなるリン酸エステルの製造方法。
Patent JP-WO2003014612-A1 (JP)
Title: 高温で使用される難接合性配管の連結方法及び構造
IPC: B23K9/04
Filed: 2001-08-08
Abstract: 高温で使用される難溶接性材料からなる配管（２、３）の端部にメスネジ（３ａ）あるいはオスネジ（２ａ）加工して配管（２、３）を互いにネジ結合するとともに、ネジ結合された配管結合部（１）の内外面、あるいは内面のみ、あるいは外面のみをシール手段（７、９）によりシールし、これにより高温で使用される難溶接性材料からなる配管（２、３）を互いにネジ構造で結合することにより配管結合部（１）の機械的強度を確保するとともに、配管結合部（１）の内外面、あるいは内面のみ、あるいは外面のみをシール手段（７、９）によりシールして前記配管結合部（１）の気密性を確保するようにした。
Patent JP-WO2003028089-A1 (JP)
Title: 半導体ウエハ検査装置
IPC: H01L21/66
Filed: 2002-09-19
Abstract: 本発明の半導体ウエハ検査装置は、半導体ウエハを吸着保持する回転テーブルと、前記回転テーブル上に保持された前記半導体ウエハの少なくともエッジ部を照明する照明装置と、前記照明装置により照明された前記半導体ウエハのエッジ部を撮像する撮像装置と、前記撮像装置により撮像された前記エッジ部の画像を取得して少なくともエッジカット量又はクラックを検出する画像処理装置と、前記画像処理装置で画像処理された前記エッジ部の画像を表示出力する表示部と、を具備している。
Patent WO-2004085052-A1 (WO)
Title: マイクロカプセルの製造法
Inventor: TAKAKURA YUKIKO
IPC: B01J13/04
Filed: 2004-03-18
Abstract: 超音波処理によりマイクロカプセルを製造する方法を提供する。　カプセル被膜の材料を０．００１～５０％含む親水性溶液１重量部に対し疎水性材料を０．０１～１０重量部含む混合溶液に０．１秒～６０分間超音波処理を行うことにより、メジアン径が０．１～１０００μｍであるマイクロカプセルを製造する。
Patent WO-2004090409-A1 (WO)
Title: 配管部材の接続構造
Inventor: HAMADA TAKESHI
IPC: F16L41/03
Filed: 2004-04-09
Abstract: 接続が簡単で、長期間にわたって受ける流体の圧力変動や温度変化等により、クリープ作用によって、接続部分の圧着力が弱まってシール性能が低下したり、緊締部材に生じた緩みにより接続部分が離間しやすくなっても液漏れを確実に防止することができる配管部材の接続構造を提供する。内部に流路を有し、流路に連通し外周に第一環状溝６を有する第一開口部７を設けた第一接合面８を備えた第一配管部材１と、内部に流路を有し、流路に連通し外周に第二環状溝９を有する第二開口部１０が設けられた第二接合面１１を備えた第二配管部材２とを、両端に鍔部２３を有し外周に弾性体２６、２７嵌着がされた薄肉の略円筒状スリーブ３が第一環状溝６と第二環状溝９に圧挿された状態で接続する。
Patent WO-2004097875-A1 (WO)
Title: モバイル機器用の多色樹脂成形部品
Inventor: YASUHARA TAKASHI
IPC: H01H13/14
Filed: 2004-04-15
Abstract: モバイル機器用の樹脂製部品の金属めっきによる加飾手段をさらに発展させて、押釦スイッチのキートップや装飾部材のより高度で多様性のあるデザインを実現すること。　目的とする押釦スイッチのキートップ又は装飾部材を異なる樹脂素材を一体に成形する多色樹脂成形法により形成し、当該樹脂製部品表面の互いに隔離された複数の領域に同一金属又は異種金属のめっき膜を付着させる。
Patent WO-2004095425-A1 (WO)
Title: 独立成分分析による音源分離処理方法、音源分離処理システム及びそのためのコンピュータソフトウエアプログラム
Inventor: IMOTO KATSUSHI
IPC: G10L21/0272
Filed: 2004-04-21
Abstract: 目的音声音源及び雑音源からそれぞれ発信される目的音声及び雑音からなる混合信号を、異なる位置に設けた第１及び第２のマイクでそれぞれ受信する混合信号受信工程と、前記各混合信号を時間領域から周波数領域にフーリエ変換し、前記目的音声及び雑音が混合される空間における音源混合特性Ｇの逆特性Ｈ（＝Ｇ−１）を独立成分分析方法によって推定する逆特性推定工程と、推定された逆特性Ｈを利用して前記受信した混合信号を目的音声の信号と雑音の信号とに分離する信号分離工程と、前記分離された目的音声の信号を周波数領域から時間領域にフーリエ逆変換して目的音声を復元する目的音声復元工程とを有する。　これにより、混合信号から目的音声を分離する精度を維持しながら分離処理時間に起因する遅延時間を短縮することができる。