baber/WOPTO huggingface dataset:
Patent WO-2020205467-A1 (WO)
Inventor: WANG SHAOMENG
IPC: A61K31/683
Filed: 2020-03-27
Abstract: The present disclosure provides compounds represented by Formulae I and IV: wherein R 1a , R 1b , R 2a , R 2b , A, E, Q D , and Q E  are as defined in the specification, and the salts and solvates thereof. Compounds of Formula I are degraders of STAT3. Compounds of Formula IV are inhibitors of STAT3. STAT3 degraders and inhibitors are useful for the treatment of cancer and other diseases.
Patent WO-2020210379-A1 (WO)
Inventor: HAO XIAOLIN
IPC: A61K31/427
Filed: 2020-04-08
Abstract: La présente invention concerne des inhibiteurs sélectifs de la phosphoinositide 3-kinase gamma de formule (I) comprenant (I-a), (I-b), (I-c), et (I-d), ou des sels pharmaceutiquement acceptables de ceux-ci. Ces composés sont utiles pour le traitement d'états médiés par un ou plusieurs isoformes de PI3K, tels que PI3K gamma (PI3Kγ). La présente invention concerne en outre des procédés d'inhibition de la phosphoinositide 3-kinase gamma à l'aide de ces composés pour le traitement de troubles liés à l'activité de la phosphatidylinositol 3-kinase gamma.
Patent WO-2020210555-A1 (WO)
Inventor: HUNT CORY
IPC: A01D75/18
Filed: 2020-04-09
Abstract: An agricultural vehicle header having a base structure, a header wing section, an articulated joint connecting the header wing section to the base structure, an actuator, a load sensor, and a controller. The actuator is configured to move the header wing section relative to the base structure between a wing lowered position and a wing raised position. the load sensor is operatively connected to the header wing section. The controller is configured to acquire load sensor data from the load sensor to evaluate a magnitude of a gravitational load on the header wing section, and prevent the actuator from moving the header wing section towards the wing raised position if the magnitude of the gravitational load exceeds a predetermined threshold load value. An agricultural combine having the header and methods of operating the same are also provided.
Patent WO-2020210631-A1 (WO)
Inventor: ROSS JOHN R
IPC: B65D41/34
Filed: 2020-04-10
Abstract: Systems, methods, and apparatuses for sealing bottles with a Roll-on Pilfer Proof (ROPP) closure and a childproof overcap are provided. More specifically, the present disclosure relates to an overcap that can be placed onto or formed onto the ROPP closure. The overcap has a retainer that secures the overcap to the ROPP closure and allows the overcap to move relative to the ROPP closure in a longitudinal axis. The overcap moves between a first position or mode of operation where the overcap can rotate about the ROPP closure and a second position or mode of operation where the overcap engages the ROPP closure to transmit a twisting or torque force to the ROPP closure and open the bottle.
Patent WO-2020214575-A1 (WO)
Inventor: ROBERTS JR HOWARD H
IPC: G01R31/317
Filed: 2020-04-14
Abstract: A method for compliance testing of a Digital Interface Board attached to Automatic Test Equipment in the testing of integrated circuit semiconductor devices using Impedance Response Profiling. The includes launching alternating voltage digital clock signals from the Pin Electronics to one or more circuit paths in the Digital Interface Board, and sampling a mix of the launched alternating voltage digital clock signals and reflected signals. The method also includes compositing time domain waveforms originating at the Pin Electronics, and generating an initial reflection response profile baseline. The method is repeated at a later predetermined time, generating a later reflection response profile. The method further includes comparing the initial reflection response profile baseline with the later reflection response profile, and determining whether the one or more circuit paths of the Digital Interface Board are in compliance with predetermined operating standards.
Patent WO-2020214621-A1 (WO)
Inventor: ZOLOTUKHIN MIKHAIL
IPC: A61M5/32
Filed: 2020-04-15
Abstract: The present invention is directed to a needle retention assembly, an injectate delivery system, a needle, and a safety mechanism, all of which are for use with an injection device. The needle retention assembly includes a needle offset nut which is configured to removably attach to a needle retention nut and to provide support to the needle. The injectate delivery system includes an injectate holding compartment, a plunger, and a resilient member. The needle has a sidewall defining a longitudinal channel and includes at least two orifices in the sidewall, but does not include an orifice at a tip of the needle. The safety mechanism includes a dual switch that includes two switch elements that are each positioned on opposing sides of a handle of the injection device.
Patent WO-2020227109-A1 (WO)
Inventor: HERTEL ALEXANDER
IPC: G06F9/00
Filed: 2020-05-01
Abstract: A method of interacting within a device-independent contextually driven application computing environment utilizing computer processes. The processes receive sensor data that is detected by a given client computing device. The sensor data pertains to a physical world interaction of the given client computing device. The processes process the sensor data and a user identification of a user to derive a current computing context that is both specific to the user and specific to a given location associated with the sensor data. The processes automatically communicate a current user interface configuration to a local browser process corresponding to the current computing context, so that the local browser process executing on the given client computing device automatically implements the current user interface configuration. The processes interacting with the local browser process according to the current computing context by selecting and automatically loading a given one of a set of context modules.
Patent WO-2020231672-A1 (WO)
Title: Procédés de séparation de para-xylène à partir de toluène
Inventor: TSAI ROBERT EDISON
IPC: C07C2/86
Filed: 2020-05-05
Abstract: L'invention concerne des procédés et des appareils pour la séparation de para-xylène. Un flux de para-xylène est séparé d'un flux de toluène dans une colonne de fractionnement. Un flux de tête de la colonne de fractionnement est comprimé puis envoyé à une zone de récupération de chaleur pour transférer la chaleur du flux de tête à un autre flux de traitement dans, par exemple, un échangeur de chaleur. La colonne de fractionnement peut être séparée d'un effluent provenant d'un réacteur de méthylation de toluène.
Patent WO-2020227346-A1 (WO)
Inventor: IGNACZAK BRIAN T
IPC: F17D5/00
Filed: 2020-05-06
Abstract: A fluid line connector and assembly provides remote securement detection capabilities and is hence equipped for initial assembly, subsequent quality inspection, and subsequent service techniques that are automated, robotic, and/or autonomous. The fluid line connector includes a body, a radio-frequency identification (RFID) tag, one or more actuator members, and one or more switches. The body has a passage for fluid-flow therethrough. The RFID tag can communicate with an RFID interrogator. The actuator member(s) changes the state of the switch(es) when the actuator member(s) actuates. The switch(es) is electrically coupled with the RFID tag.
Patent WO-2020251793-A1 (WO)
Inventor: ALBRIGHT STEVEN TODD
IPC: B65D17/28
Filed: 2020-06-01
Abstract: A can end includes a center panel, an annular portion disposed about the center panel, a chuck wall disposed about the annular portion, a curl extending radially outwardly from the chuck wall, the annular portion including a subsurface step.
Patent WO-2020247923-A1 (WO)
Inventor: DUNFORD DOUGLAS WILLIAM
IPC: E21B17/08
Filed: 2020-06-08
Abstract: A threaded pipe connection includes a first tubular member having a pin end defining external threads, a second tubular member having a box end defining internal threads threadably engageable with the external threads of the pin end, and a thread profile that defines at least a portion of one of the internal or external threads and includes a crest, a root, and a transition surface extending between the crest and the root. The transition surface includes a first arcuate surface extending from a top of the crest at a first radius, a second arcuate surface extending from the first arcuate surface at a second radius, and a third arcuate surface extending from the second arcuate surface at a third radius. The first radius and the third radius are each smaller than the second radius.
Patent WO-2020252338-A1 (WO)
Title: Device and method for storing and supporting a smokable sleeve
Inventor: AHMED KAZI
IPC: A24C5/42
Filed: 2020-06-12
Abstract: A device for storing and supporting a smokabie sleeve comprises a body defining a chamber for storing the smokabie sleeve, and a sleeve holder connected to the body for supporting the sleeve in a tillable position, the sleeve holder comprising an aperture for releasably receiving the sleeve. The device may comprise two or more spaced apertures for receiving a sleeve or a plurality of sleeves. The sleeve holder may be integrally formed with the body or releasably connected to the body such that the sleeve holder is disposed either outside of the chamber or within the chamber. The device may be a rigid or resilient material such as plastic, cardboard, or paper.
Patent WO-2020252436-A1 (WO)
Inventor: DE BOER ALEXANDRA SOPHIE
IPC: C12N5/10
Filed: 2020-06-14
Abstract: This invention relates generally to pharmaceutical compositions and preparations of circular polyribonucleotides and uses thereof in cellular therapy.
Patent WO-2020263838-A1 (WO)
Title: Virtual location selection for virtual content
Inventor: WARREN SILAS
IPC: G06F3/01
Filed: 2020-06-23
Abstract: A method for placing content in an augmented reality system. A notification is received regarding availability of new content to display in the augmented reality system. A confirmation is received that indicates acceptance of the new content. Three dimensional information that describes the physical environment is provided, to an external computing device, to enable the external computing device to be used for selecting an assigned location in the physical environment for the new content. Location information is received, from the external computing device, that indicates the assigned location. A display location on a display system of the augmented reality system at which to display the new content so that the new content appears to the user to be displayed as an overlay at the assigned location in the physical environment is determined, based on the location information. The new content is displayed on the display system at the display location.
Patent WO-2021021351-A1 (WO)
Title: Surveillance de traitement de substrat
Inventor: ZHU ZUOMING
IPC: H01L21/67
Filed: 2020-06-26
Abstract: Un procédé de traitement d'un substrat à l'intérieur d'une chambre de traitement comprend la réception d'un premier signal de rayonnement correspondant à un film sur un élément cible disposé à l'intérieur de la chambre de traitement, l'analyse du premier signal de rayonnement, et la commande du traitement du substrat sur la base du premier signal de rayonnement analysé. La chambre de traitement comprend un support de substrat conçu pour supporter le substrat à l'intérieur d'un volume de traitement et un dispositif de commande couplé à un premier dispositif de détection conçu pour recevoir le premier signal de rayonnement.
Patent WO-2020264275-A1 (WO)
Title: Dynamic code loading for multiple executions on a sequential processor
Inventor: JACOB SAMUEL
IPC: G06F8/41
Filed: 2020-06-26
Abstract: Embodiments include techniques for enabling execution of N inferences on an execution engine of a neural network device. Instruction code for a single inference is stored in a memory (312) that is accessible by a DMA engine, the instruction code forming a regular code block. A NOP code block (302) and a reset code block (304) for resetting an instruction DMA queue are stored in the memory (312). The instruction DMA queue (362a) is generated such that, when it is executed by the DMA engine, it causes the DMA engine to copy, for each of N inferences, both the regular code block and an additional code block to an instruction buffer (350). The additional code block is the NOP code block (302) for the first N- I inferences and is the reset code block (304) for the Nthinference. When the reset code block (304) is executed by the exeuction engine the instruction DMA queue (362a) is reset.
Patent WO-2022005488-A1 (WO)
Title: Methods and apparatus for determining radioablation treatment
Inventor: JOHNSON LEIGH SCOTT
IPC: G06T19/00
Filed: 2020-07-03
Abstract: Systems and methods for cardiac radioablation treatment planning are disclosed. In some examples, a computing device receives an image volume and a dose matrix data. The computing device generates a first mesh of organ substructures for the organ based on substructure contours for the organ. Further, the computing device generates a second mesh of an isodose volume based on the dose matrix data. The computing device displays the first mesh of the organ substructures and the second mesh of the isodose volume within a same scene. In some examples, the computing device samples a plurality of dosage values, determines representative dosage values for each of a plurality of points along surfaces of a dose matrix, and generates an image for display based on the representative dosage values. In some examples, a segmentation model is generated for display based on the representative dosage values.
Patent WO-2021016403-A1 (WO)
Title: Method, apparatus and system to detect indels and tandem duplications using single cell dna sequencing
Inventor: MANIVANNAN MANIMOZHI
IPC: C40B20/04
Filed: 2020-07-22
Abstract: The disclosure relates to method, apparatus and system to detect indels using single cell DNA sequencing. A method to detect one or more indel variants in a single cell DNA sequence may include the steps of: (1 ) obtaining a plurality of sequenced data sets from a cell sample having one or more indel variants; (2) processing the plurality of sequenced data sets to identify a region of interest (ROI); (3) mapping each ROI to a known genome to identify target loci that do not map to the genome; (4) selecting a subset of the mapped ROIs with acceptable reads to identify a group of cells of interest; (5) from the selected subset, identifying one or more soft-clipped reads to identify a group of indel variants; and (6) determining at least one of location or frequency of occurrence for each indel variant of the identified group with respect to the corresponding ROI.
Patent WO-2021016544-A1 (WO)
Title: Event-based classification of features in a reconfigurable and temporally coded convolutional spiking neural network
Inventor: VAN DER MADE PETER AJ
IPC: G06G7/00
Filed: 2020-07-24
Abstract: Embodiments of the present invention provides a system and method of learning and classifying features to identify objects in images using a temporally coded deep spiking neural network, a classifying method by using a reconfigurable spiking neural network device or software comprising configuration logic, a plurality of reconfigurable spiking neurons and a second plurality of synapses. The spiking neural network device or software further comprises a plurality of user-selectable convolution and pooling engines. Each fully connected and convolution engine is capable of learning features, thus producing a plurality of feature map layers corresponding to a plurality of regions respectively, each of the convolution engines being used for obtaining a response of a neuron in the corresponding region. The neurons are modeled as Integrate and Fire neurons with a non-linear time constant, forming individual integrating threshold units with a spike output, eliminating the need for multiplication and addition of floating-point numbers.
Patent WO-2021035113-A1 (WO)
Title: Gait-related devices and methods including articles for manufacture of sensors
Inventor: JURATOVAC JOSEPH A
IPC: A43B3/00
Filed: 2020-08-21
Abstract: Described in this disclosure are devices, systems and methods including an article of manufacture for attachment to a foot or footwear comprising a trapezoidal shaped apparatus, wherein the trapezoidal shaped apparatus has a front, a back, wide end, a narrow end, a length, a thickness, a medial edge, and a lateral edge, and wherein the trapezoidal shaped apparatus has a plurality of distinct ridges on its lateral and medial edges.
Patent WO-2021041230-A1 (WO)
Inventor: DELANEY JR
IPC: C08L71/02
Filed: 2020-08-21
Abstract: La présente invention concerne, selon certains aspects, un polymère qui comprend une pluralité de bras polymères, une première partie des bras polymères comprenant chacun un groupe terminal réactif et une seconde partie des bras polymères comprenant chacun une fraction aromatique radio-opaque contenant une structure aromatique monocyclique ou polycyclique ayant une pluralité de groupes fonctionnels radio-opaques et une pluralité de groupes fonctionnels hydrophiles. La présente invention concerne, selon certains aspects, des systèmes qui comprennent (a) une première composition comprenant un tel polymère radio-opaque et (b) une seconde composition comprenant un composé multifonctionnel contenant des groupes fonctionnels réactifs qui sont réactifs avec le groupe terminal réactif. La présente invention concerne, selon certains aspects, des produits de réaction réticulés (a) d'un tel polymère radio-opaque et (b) d'un composé multifonctionnel contenant des groupes fonctionnels réactifs qui sont réactifs avec le groupe terminal réactif.
Patent WO-2022046068-A1 (WO)
Inventor: SANTOS DA SILVA JUNIOR ALEXANDRE
IPC: G06F11/34
Filed: 2020-08-28
Abstract: An example computing device includes a user input device, a network interface, and a processor connected to the user input device and the network interface. The processor is to execute a process, monitor user input at the user input device to determine user interaction with the process, and, in response to determining a lack of user interaction with the process, provide the process to a remote computing device via the network interface to continue execution of the process by the remote computing device.
Patent WO-2021055276-A1 (WO)
Title: Compact, differential, coaxial inductive force sensor
Inventor: PETERSEN ALAN W
IPC: A61B34/00
Filed: 2020-09-14
Abstract: A variety of applications can include apparatus and/or methods that provide an axial force transducer. Two coils wound coaxially with respect to each other can be used with a magnet to determine a distance traveled based on application of an axial force to an instrument component. The two coils and magnet can be configured in a number of ways with respect to the instrument component. In various embodiments, the difference between an inductance associated with one of the two coils along with its relation to the magnet and an inductance associated with the other one of the two coils along with its relation to the magnet can be used to determine the axial force on the component of the instrument associated with the distance travelled. Additional apparatus, systems, and methods are disclosed.
Patent WO-2021067026-A1 (WO)
Title: Crimped end connection for flexible hose
Inventor: GUTMANN DANIEL
IPC: F16L33/207
Filed: 2020-09-15
Abstract: A hose assembly includes a hose, a connector body, and a collar. The connector body has an outer end portion defining a fluid connector, an inner end defining a nose portion received in an inner bore of the hose end portion, and an intermediate portion including first and second annular flanges spaced apart to define a dog lock groove. The collar includes an outer end portion defining an inner radial dog lock received in the dog lock groove, an annular step portion extending radially outward of and axially inward of the dog lock in axial alignment with the first annular flange, and an inner end portion extending radially outward of and axially inward from the step portion, the inner end portion being in radial compression against an outer surface of the hose end portion.
Patent WO-2021071924-A1 (WO)
Title: High flow capacity flexible earth drainage system and method for relieving and conveying pore water
Inventor: CASE JOHN E
IPC: E02B11/00
Filed: 2020-10-07
Abstract: A high flow capacity flexible earth drainage system and method for relieving and conveying pore water is disclosed. In some embodiments, the presently disclosed high flow capacity flexible earth drainage system and method provide an arrangement of high flow capacity flexible earth drains, wherein each flexible earth drain may include one or more flexible ridged panels, one or more single-sided flexible ridged panels, one or more two-sided flexible ridged panels, and/or one or more flexible zigzag panels arranged longitudinal within a geotextile filter fabric sleeve. Further, a method is provided of installing the high flow capacity flexible earth drains to form the presently disclosed high flow capacity flexible earth drainage system for relieving and conveying pore water.
Patent WO-2021072357-A1 (WO)
Title: Melt-compounded polyamide graphene composites
Inventor: SHABAFROOZ VAHID
IPC: B29B11/16
Filed: 2020-10-12
Abstract: A graphene-reinforced polyamide composite material and a process to make the material are provided. The graphene-reinforced polyamide composite material has graphene-based nanofillers dispersed in polyamide resins during a melt compounding manufacturing process. The graphene-based nanofillers are selected from a group of single-layer graphene, double-layer graphene, multi-layer graphene, graphene nanoplatelet, doped graphene, graphene oxide, reduced graphene oxide, and a combination thereof.
Patent WO-2021092053-A1 (WO)
Title: Mcl-1 inhibitor macrocycle compounds for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
Inventor: HUDSON RYAN
IPC: C07D471/04
Filed: 2020-11-04
Abstract: This disclosure provides small-molecule compounds with Mcl-l inhibitory activity. Compounds provided in this disclosure promote apoptosis in senescent cells, particularly when combined with inhibitors of other Bcl family proteins. Compounds provided in this disclosure also promote apoptosis in cancer cells. Such compounds can be developed for treating senescent-related conditions, or as chemotherapeutic agents.
Patent WO-2021097417-A1 (WO)
Title: Linkable tiles for covering a surface
Inventor: BRITTON JEREMY
IPC: E04B1/41
Filed: 2020-11-16
Abstract: Various embodiments of interconnectable pieces are described that collectively form a surface. The pieces comprise one or more routed edges or cutouts that can be configured to receive an insert used to couple adjacent tiles to one another. Some inserts may comprise one or more magnets or magnetized portions to magnetically couple the pieces with adjacent pieces.
Patent WO-2021101868-A1 (WO)
Inventor: LIU DAVID S
IPC: C09K3/00
Filed: 2020-11-17
Abstract: The invention relates to the use of compatible, semi-miscible or miscible polymer compositions as support structures for the 3D printing of objects, including those made from polyether-block-amide copolymers such as PEBAX® block copolymers from Arkema, polyamides such as RILSAN® polyamides from Arkema, polyether ketone ketone such as KEPSTAN® PEKK from Arkema, and fluoropolymers, such a KYNAR® PVDF from Arkema, especially objects of polyvinylidene fluoride and its copolymers. One particularly useful miscible polymer is an acrylic polymer, which is miscible with the fluoropolymer in the melt. The support structure composition provides the needed adhesion to the build plate and to the printed object and support strength during the 3D printing process, yet it is removable after the fluoropolymer object has cooled. The support polymer composition is selected to be stiff and low warping, yet flexible enough to be formed into filaments.