baber/WOPTO huggingface dataset:
Patent NZ-582850-A (NZ)
Title: 5'-substituted adenosynes, preparation thereof and use as inhibitors of s-adenosylmethionine decarboxylase
Inventor: SECRIST JOHN A III
IPC: A01N43/04
Filed: 2008-08-01
Abstract: Disclosed is a crystal structure of the complex of S-adenosylmethionine methyl ester with hAdoMetDC F223A, a mutant where the stacking of the aromatic rings of F7, adenine and F223 would be eliminated. The structure of this mutant with the ester shows that the ligand still maintains a syn conformation aided by pi-pi interactions to F7, hydrogen bonds to the backbone of Glu67, and electrostatic interactions. Several series of AdoMet substrate analogues with a variety of substituents at the 8 position of adenine were synthesized and analysed for their ability to inhibit hAdoMetDC. To understand these results, virtual modelling of the enzyme inhibitor complexes and the crystal structures of human AdoMetDC with 5'-deoxy-5'-[N-methyl-N-[2- (aminooxy)ethyl]amino-8-rnethyl]adenosine (MAOEMA) and 5'-deoxy-5'-[N-methyl-N-[4- (aminooxy)butyl]amino-8-ethyl]adenosine (MAOBEA) at the active site have been determined experimentally.
Patent NZ-583198-A (NZ)
Title: Ramp section extending transversely from longitudinal edge of track
Inventor: CAMPBELL GEORGE GILES
IPC: A47B53/00
Filed: 2008-08-18
Abstract: A ramp assembly for a mobile shelving system including at least one longitudinal track body having a central channel and transverse edges. The ramp assembly includes a plurality of ramp sections (114) disposed on either side of the track body. Each ramp section includes a hooked edge (118) adapted to rotatably engage a transverse edge of the track body, the angle of the ramp section being adjustable by way of rotation of the ramp section to thereby accommodate track bodies of different height.
Patent NZ-583231-A (NZ)
Title: Guide arrangement for developer container in image forming apparatus
Inventor: KOSHIMORI KAZUNORI
IPC: G03G15/06
Filed: 2010-02-10
Abstract: An image forming agent storage container (300) includes a container body), a driven transmission member, and a guide part (394). The container body stores an image forming agent. The container body is configured to be mounted to an image forming apparatus body (20). The driven transmission member is provided along a side face of the container body (310a). A driving force is transmitted to the driven transmission member. The guide part (394) guides mounting of the container body (310a) to the image forming apparatus body (20). The guide part (394) is located in a position anterior to the driven transmission member (370) in a mounting direction in which the container body is mounted to the image forming apparatus body. The guide part (394) is provided so as to project in a direction away from the side face of the container body.
Patent NZ-589490-A (NZ)
Title: Fiber photovoltaic devices and methods for production thereof
Inventor: CURRAN SEAMUS
IPC: H01G9/20
Filed: 2009-05-27
Abstract: 589490 Disclosed is a fibre photovoltaic device. The fibre photovoltaic device is comprised of an optical filament, a first electrode layer, a continuous semiconductive layer and a second electrode layer. The first electrode layer coats the optical filament and is at least partially transparent to electromagnetic radiation. The continuous semiconductive layer is deposited above the first electrode layer and is in electrical contact with the first electrode layer. The continuous semiconductive layer absorbs electromagnetic radiation and turns the electromagnetic radiation into an electrical signal. The continuous semiconductive layer comprises at least two semiconductive materials that are substantially unmixed and are located in separate regions along the longitudinal axis of the fibre photovoltaic device. The second electrode layer is deposited above the continuous semiconductive layer and is in electrical contact with the continuous semiconductive layer.
Patent NZ-590483-A (NZ)
Title: Pyridazine derivatives as hedgehog and smooothened signal pathway inhibitors
Inventor: MILLER-MOSLIN KAREN
IPC: C07D401/12
Filed: 2009-07-16
Abstract: Disclosed are pyridazine-containing compounds and pharmaceutical compositions of Formula (I), salts thereof, and methods for their preparation. Specific examples of compounds of Formula (I) include 2-[(R)-4-(6-Benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-propan-2-ol, 2-{ (R)-4-[6-(Hyrdoxyl-phenyl-methyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5'-yl]-propan-2-ol, and 1-[(R)-4-(6-Benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-ethanone. Also disclosed is a method of treating a disease, disorder or syndrome associated with Smoothened inhibition, such as cancer or inflammation, which comprises the administration of a compound or pharmaceutical of Formula (I). Treatable cancers include medulloblastoma, basal cell carcinoma, pancreatic cancer, and small cell lung cancer.
Patent NZ-591915-A (NZ)
Title: Dose delivering device for administering opioids, including deactivation means
Inventor: CASTILE JONATHAN
IPC: A61M15/08
Filed: 2009-09-28
Abstract: In the field of pain relief and treatment there is a need for a device which is able to administer several predetermined doses of an opioid analgesic in a manner which can be done simply and safely by a patient or carer; in particular in a manner which minimises the risk of administering too great a dose at any one time. A device (10), for administering a predefined number (N) of predefined volume unit doses (Vu) of an opioid analgesic in liquid form, includes a closed container (12) which contains a predetermined fill volume (Vf) of the opioid analgesic, and a dispenser (14) that is connected to the container. The dispenser is operable to administer an individual one volume unit dose repeatedly the predefined number of times. Both the dispenser is adapted, and the concentration of the opioid analgesic is chosen such that the volume unit dose is in the range 0.05 to 0.15ml.
Patent NZ-594283-A (NZ)
Title: An infusion assembly including two-part infusion chamber with relatively displacable parts
Inventor: PAGANO GAETANO
IPC: A47J31/36
Filed: 2009-12-29
Abstract: An infusion assembly includes an abutment member and a receiving member (7) adapted to assume, in a stationary support and guide structure, a separated open position, as well as a coupled closed position in which an infusion chamber is defined. The relative movement of the abutment and receiving members is controlled using an electrical linear actuator. The receiving member comprises a first body (108), mounted in the support and guide structure, moveably to and from the abutment member, and a second body (8), insertable into and removable from the first body, and in which there is a cavity (9) cooperating to define the infusion chamber.
Patent NZ-596989-A (NZ)
Title: Aerosol generator
Inventor: SCHENNUM STEVEN MICHAEL
IPC: A24F42/60
Filed: 2010-05-13
Abstract: 596989 A portable, handheld breath-actuated aerosol generator comprises a generally cylindrical body that comprises body portions 1, 3 that receive a canister of pressured fluid, such as a nicotine containing liquid to be inhaled as an aerosol by a user, a mouthpiece 7 in the first body portion 1 configured to deliver an amount of the aerosol to the mouth of the user from the canister. A trigger is cocked ready for releasing pressurized fluid from the canister by manually sliding the body portions 1, 3 towards one another. The trigger comprises a compression spring 26 and a cam 33 which engages a pressure sensitive puff lever with a plate 29 that releases the cocked trigger when a user sucks on the mouthpiece and draws in air through air inlet opening. Release of the trigger releases spring 26 which slides the body portions apart and also opens a valve in the canister so as to deliver the aerosol to the mouthpiece.
Patent NZ-597526-A (NZ)
Title: Antitumoral compounds
Inventor: RODRIGUEZ VICENTE ALBERTO
IPC: A61K31/351
Filed: 2008-12-19
Abstract: Disclosed are unsaturated 2-hydroxy-pyran-6-yl alkyl amides as represented by the general formulae (I) and A, wherein: Y is selected from -CHRay-, -CHRay-CHRby-, -CRay=CRby-, -C=C-, -CHRayCHRby-CHRcy-, -CHRay-CRby=CRcy-, and -CHRay-C=C-; each Ray, Rby, and Rcy is independently selected from hydrogen, substituted or unsubstituted alkyl, alkenyl or alkynyl; each R1, R2, R3, R4, and R5 is independently selected from hydrogen, substituted or unsubstituted alkyl, alkenyl, or alkynyl; R6 is selected from NR8R9 and OR10; W is selected from oxygen and NR7; and wherein the remaining substituents are as defined herein. Further disclosed is a pharmaceutical composition which comprises a compound as defined above, or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, and a pharmaceutically acceptable diluent or carrier for the treatment of cancer.
Patent NZ-597937-A (NZ)
Title: Easy open and reclosable package with discrete laminate having panel section with easy-open sealant
Inventor: MOEHLENBROCK ANDREW W
IPC: B31B50/62
Filed: 2010-07-30
Abstract: 597937 An easy-open and reclosable package includes a pouch including a discrete laminate including a tape including a base strip coated with a pressure sensitive adhesive, and a panel section, the inner surface of the panel section having an easy- open sealant, the panel section adhered by the PSA to the base strip; the discrete laminate anchored to a first side panel; and a product in the pouch. When the package is opened, the package can be reclosed by adhering the first or second side panel to the pressure sensitive adhesive. Methods for making the package, and a pouch, are also disclosed.
Patent NZ-598354-A (NZ)
Title: New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
Inventor: PEGLION JEAN-LOUIS
IPC: C07C309/66
Filed: 2010-09-17
Abstract: The disclosure relates to a method for synthesizing ivabradine of formula (I) and to the addition salts thereof with a pharmaceutically acceptable acid. The process disclosed comprises the compound of formula (VIII) wherein X represents a halogen atom, a mesylate group or a tosylate group, is subjected to an alkylation reaction with the compound of formula (IX) wherein A represents H2C-CH2 or HC=CH, in the presence of a base,in an organic solvent,to yield the compound of formula (VII) wherein A is as defined hereinbefore, and then, in the case where A represents H2C-CH2, ivabradine of formula (I), a particular case of the compounds of formula (VII) and product of the alkylation reaction of the compound of formula (VIII) with the compound of formula (IX), is isolated and purified and then may be converted into its addition salts with a pharmaceutically acceptable acid selected from hydrochloric acid, hydrobromic acid, sulphuric acid, phosphoric acid, acetic acid, trifluoroacetic acid, lactic acid, pyruvic acid, malonic acid, succinic acid, glutaric acid, fumaric acid, tartaric acid,maleic acid, citric acid, ascorbic acid, oxalic acid, methanesulphonic acid, benzenesulphonic acid and camphoric acid, and into hydrates thereof, in the case where A represents CH=CH, the compound of formula (IV), product of the alkylation reaction of the compound of formula (VIII) with the compound of formula (IX), is subjected to a catalytic hydrogenation reaction to yield ivabradine of formula (I), which is isolated and purified and then may be converted into its addition salts with a pharmaceutically acceptable acid selected from hydrochloric acid, hydrobromic acid, sulphuric acid, phosphoric acid, acetic acid, trifluoroacetic acid, lactic acid, pyruvic acid, malonic acid, succinic acid, glutaric acid, fumaric acid, tartaric acid, maleic acid, citric acid, ascorbic acid, oxalic acid, methanesulphonic acid, benzenesulphonic acid and camphoric acid, and into hydrates thereof
Patent NZ-605432-A (NZ)
Title: 2-(arylamino)-3h-imidazo[4,5-b]pyridine-6-carboxamide derivatives and their use as mpges-1 inhibitors
Inventor: PRIEPKE HENNING
IPC: C07D471/04
Filed: 2011-08-19
Abstract: Disclosed are imidazo[4,5-b]pyridines of formula (I) for example N-{ 2,4-dichloro-3-[6-(trans-4-trifluoromethyl-cyclohexylcarbamoyl)-5-(2,2-difluoro-ethoxy)-3-methyl-3H-imidazo[4,5-b]pyridin-2-ylamino]benzyl} -2,2-dimethyl-propionamide, their use as inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1), pharmaceutical compositions containing them, and use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions.
Patent NZ-610394-A (NZ)
Title: Sprinkler assembly for attachment to a piping system
Inventor: ORR SHAWN G
IPC: A62C37/08
Filed: 2011-08-02
Abstract: A sprinkler assembly utilising adapters and fittings to attach to fire extinguishing systems. The assembly has a sprinkler body (102) having opposite first and second ends and a threaded section (154) adjacent the first end. A thermally responsive element is mounted to the sprinkler body. An adapter (106) has opposite third (108) and fourth (110) ends and an internal passageway (112) extending there between, the third end (108) configured to attach to an access member of a piping system in fluid communication with the passageway (112). The passageway (112) has a threaded section (114) adjacent the fourth end (110), and the threaded section (114) includes a straight thread. The passageway (112) includes an annular recess section (116) having an outer wall with an inner diameter that is larger than an inner diameter of the threaded section (114) of the adapter (106) and a shoulder (140) is disposed at an upstream end of the annular recess section (116). A resilient seal member (118) is disposed in the annular recess section (116) against the shoulder (140) of the passageway (112) of the adapter (106) adjacent the threaded section (114). The first end of the sprinkler body (102) engages with and compresses the seal member (118) when the threaded section (154) of the sprinkler body (102) is engaged with the threaded section (114) of the passageway (112) and forms a fluid-tight seal between the adapter (106) and the sprinkler body (102).
Patent NZ-620330-A (NZ)
Title: Systems and methods for manufacturing fibers with enhanced thermal performance
Inventor: CHOUDHARY MANOJ KUMAR
IPC: E04B1/74
Filed: 2012-07-12
Abstract: A method of producing glass fibres having inclusions that change the absorption and refractive index of the fibres. In the method a molten material is supplied to a fibre forming apparatus. A controlled amount of particulate is added to the molten material which is formed into fibres (F). An undissolved portion of the added particulate forms inclusions (i) in the fibres, the inclusions having an absorption index in a 2-7 μm wavelength region that is greater than a corresponding absorption index of the material. The material of the particulate has a melting temperature that is greater than a temperature of the molten glass material when the particulate is added to the molten glass material. To maintain structural integrity of the fibres, the diameter (d) of the inclusions are limited to a predetermined fraction of the diameter (D) of the fibres, for example about one half or less of the diameter. The fibres are used in an insulation product (A).
Patent NZ-628188-A (NZ)
Title: System for providing product quality information and traceability to customers including x-ray images of can packed food products
Inventor: QING YE
IPC: G11B7/00
Filed: 2014-09-05
Abstract: Disclosed is a method of providing information relating to a product unit to a client device. The method includes applying a plurality of product unit identification means to a plurality of product units, each product unit identification means comprising a product unit identifier unique to the respective product unit. The method also includes collecting product unit quality information specific to each of the product units and storing the product unit quality information for each of the product units in association with the respective product unit identifier. The method further includes receiving a request identifying a selected one of the product unit identifiers and sending the product unit quality information corresponding to the selected product unit identifier to the client device.
Patent NZ-631030-A (NZ)
Title: A conveying device
Inventor: ROY NOEL TUCKER ROBINSON
IPC: B65G65/00
Filed: 2014-09-12
Abstract: Disclosed are an automated carton transfer system (100) and a method of operating an automated carton transfer system (100). The disclosure notes it is important to efficiently use mobile robotic storage and retrieval platforms to maintain overall system performance; therefore pre-sorting cartons in like lots optimises a cranes performance. The automated carton transfer system (100) includes a delivery conveyor (102), at least one pre-sort buffer conveyor, a plurality of outfeed positions (114), at least one conveying device (200), at least one carton actuation device, a plurality of storage racks, at least one robotic storage and retrieval platform (116) and at least one controller. The delivery conveyor (102) conveys a sequence of cartons (104a-104g). The at least one pre-sort buffer conveyor receives the sequence of cartons (104a-104g). The at least one conveying device (200) moves individual cartons (104a-104g) received from the delivery conveyor (102) along a series of loading positions (110) aligned with the outfeed positions (114). The at least one carton actuation devices moves a selected carton (104a-104g) from a loading position on the conveying device (200) to a selected outfeed position (114). The storage racks have a plurality of storage positions. The robotic storage and retrieval platform (116) loads cartons (104a-104g) from the outfeed positions (114) and transports them to selected storage positions within the storage racks. The controller controls operation of the pre-sort buffer conveyor and the at least one robotic storage and retrieval platform (116).
Patent NZ-631832-A (NZ)
Title: Spring retractable reel with gear assembly
Inventor: MORGAN SEAN
IPC: B67D7/40
Filed: 2013-12-20
Abstract: An assembly for a heavy duty spring motor for controlling recoil or resistance to paying-out of a hose reel is described. The assembly seeks to increase the number of rotations undertaken during recoil to allow for the storage of more hose on the spool or drum. The assembly consists of a gear box or assembly (280), a brake mechanism (270), and a spring motor (250) all of which are modular, stackable cassette components. The rotation of the spring motor is regulated by the brake mechanism and the gear assembly modifies the ratio of turns of the spring motor.
Patent NZ-701082-A (NZ)
Title: Adapter stabilization for bucket lip
Inventor: CAMPOMANES PATRICK
IPC: E02F9/28
Filed: 2013-03-12
Abstract: A ground engaging support structure such as an adapter is mounted on the front edge of an excavating bucket lip in a manner inhibiting side-to-side movement of the installed adapter, and shielding the front bucket lip edge from operational wear at the adapter installation location using opposing tapered block members secured to the front lip edge for movement toward a forwardly projecting stabilizing portion of the lip edge. The adapter is telescoped onto the front lip edge over its stabilizing projection, correspondingly tapered portions of the adapter engage the block members and move them toward one another and toward the stabilizing projection. Rear leg portions of the adapter are then suitably secured to the bucket lip. The repositioned block members interposed between adapter the front bucket lip edge then inhibit side-to-side shifting of the installed adapter while also shielding the lip edge from operational abrasion wear.
Patent NZ-711208-A (NZ)
Title: High-energy composite peptide selenoprotein nutrient solution, preparation method and application thereof
Inventor: XIE CHAO
IPC: C05G3/00
Filed: 2013-12-26
Abstract: The present invention relates to a high-energy composite peptide selenoprotein nutrient solution, a preparation method and an application thereof. The nutrient solution is formed by materials such as a selenium raw material, a protein, a mineral substance, a vitamin, and a natural energy mineral. The high-energy composite peptide selenoprotein nutrient solution containing rich selenium element, the mineral substance, the vitamin and the natural energy substance is prepared by performing enzymolysis treatment on the protein, and performing synthesizing, energy treatment, complexation reaction and strengthening treatment on a peptide selenoprotein compound. The nutrient solution can be widely used in the development and utilization of various selenium-rich agricultural and sideline products (comprising various food crops, vegetables, fruits, fungi, wild plants, marine food, animal meat and Chinese medicinal herbs). The application is as follows: the high-energy composite peptide selenoprotein nutrient solution mother solution is diluted by 6000 to 8000 times by adding water, the diluted nutrient solution is irrigated and sprayed to the roots and leaf surfaces of the crops in different growth periods for 3 to 6 times, and therefore, agricultural and sideline products meeting selenium-rich standards can be obtained, and the like.
Patent NZ-720789-A (NZ)
Title: Hand trolley
Inventor: TRAPNELL KEVIN EDWARD
IPC: B62B5/00
Filed: 2011-08-22
Abstract: Disclosed is a hand trolley with a foot operated lifting platform for easier raising of loads. The hand truck includes a main body and a lifting platform movable relative to the main body for applying a lifting force to a load by a foot force applied by a foot of an operator. At least one axle is connected to the main body defining a rotational axis of the hand trolley. The foot force is applied on the same side of the rotational axis as the lifting platform such that the foot force and a weight of the load act in the same direction around the rotational axis.
Patent NZ-750798-A (NZ)
Title: Controlling process gases
Inventor: MEDOFF MARSHALL
IPC: B01J19/08
Filed: 2014-03-07
Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, equipment, systems and methods are described that can be used to treat feedstock materials, such as cellulosic and/or lignocellulosic materials, in a vault in which hazardous gases are removed, destroyed and/or converted. The treatments are efficient and can reduce the recalcitrance of the lignocellulosic material so that it is easier to produce an intermediate or product, e.g., sugars, alcohols, sugar alcohols and energy, from the lignocellulosic material.
Patent NZ-768122-A (NZ)
Title: Intraocular shunt inserter
Inventor: ROMODA LASZLO O
IPC: A61F9/007
Filed: 2018-03-09
Abstract: Glaucoma is a disease of the eye that affects millions of people. Glaucoma may be treated in a number of different ways. Glaucoma filtration surgery is a surgical procedure typically used to treat glaucoma. In one particular method, an intraocular shunt is implanted with an inserter by directing a needle, which holds the shunt through the cornea, across the anterior chamber, and through the trabecular meshwork and sclera, and into the subconjunctival space. Existing inserters may have components that move inadvertently and may not always provide desired levels of precision and feedback during a procedure. An inserter can include a housing and a slider component. The slider component can be coupled to the housing and positioned along an outer surface thereof. The slider component can be slidable along an elongate slot of the housing and include a guide tab disposed within a guide channel of the housing body. The slider can include a friction tab having a biasing member configured to urge against the housing body to urge the guide tab against a wall of the guide channel. Further, a deflector component can be provided that includes a needle guide configured to receive the needle of the inserter therein. The deflector component can be removably coupled to the inserter in order to permit the needle guide to bend the needle and maintain the needle in a bended configuration.