baber/WOPTO huggingface dataset:
Patent PT-89054-A (PT)
Inventor: MCCARTHY PETER ANDREW
IPC: A61K31/16
Filed: 1988-11-23
Abstract: A compound having the formula <CHEM>  wherein R is hydrogen, (C1-C3)alkyl, phenyl, benzyl or a conventional radical forming an ester group which is hydrolyzable under physiological conditions; X is F, Cl, Br, I, (C1-C3)alkyl, CF3, benzyl, (C1-C3)alkoxy, (C2-C4)alkanoyloxy or (C2-C4)alkoxycarbonyl; and X<1>, X<2> and X<3> are each independently hydrogen, F, Cl, Br, I, (C1-C3)alkyl, CF3, benzyl, (C1-C3)alkoxy, (C2-C4)alkanoyloxy or (C2-C4)alkoxycarbonyl; or a pharmaceutically acceptable cationic salt thereof when R is hydrogen.   2. A compound of claim 1 wherein R is a radical selected from the group consisting of:  furan-5(1H)-on-1-yl;  isobenzofuran-3(1H)-on-1-yl;  3,4-dihydrofuran-5(1H)-on-1-yl;  -CHR<1>OCOR<2>, and  -CHR<1>OCOOR<2>;  wherein  R<1> is hydrogen or methyl; and  R<2> is (C1-C6)alkyl. 3. A compound of claim 1 wherein R is hydrogen, (C1-C3)alkyl, phenyl or benzyl.   4. A compound of claim 3 wherein R is hydrogen. 5. The compound of claim 4 wherein X is 3-methyl, X<1> is 5-methyl, X<3> is 3 min -methyl and X<4> is 4 min -fluoro.   The compounds are blood cholesterol lowering agents and so are useful in the prevention and treatment or cardiovascular diseases such as atherosclerosis.
Patent PT-90676-A (PT)
Inventor: ENGLAND DOUGLAS ROY
IPC: B29C65/74
Filed: 1989-05-29
Abstract: A die for use in heat welding a plastics motif to a textile base as a first welding ledge extending along a first, substantially planar face of the die, the welding ledge having a coplanar welding surface lying at least 4 mm. above the die face and having a cutting edge projecting above the welding surface to a height of at least 0.3 mm. The width of the welding surface is not less than 0.5 mm and is preferably between 1.5 mm and 3 mm. The die also has further welding ledges on which the welding surface extends the full width of the ledge. Each welding surface serves to weld the plastics material to the textile whilst the cutting edge severs excess material from the plastics motif along a welded line.
Patent PT-92717-A (PT)
Inventor: NIELSEN FLEMMING ELMELUND
IPC: A61P25/20
Filed: 1989-12-22
Abstract: Heterocyclic dihydroxyquinoxaline compounds having the formula <CHEM>  wherein R<1> is hydroxy, alkoxy, aryloxy, aralkyloxy, cycloalkylalkoxy, cycloalkoxy, or acyloxy; R<5> and R<6> together form a further fused ring, which is substituted with hydrogen, halogen or CN, and R<7> and R<8> independently are hydrogen, NO2, halogen, CN, SO2NR min R min , SO2R min , CF3, or OR min , wherein R min  is hydrogen or C1-4-alkyl; or R<7> and R<8> together form a further fused ring, which is substituted with hydrogen, halogen or CN, and R<5> and R<6> independently are hydrogen, NO2, halogen, CN, SO2NR min R min , SO2R min , CF3, or OR min , wherein R min  is hydrogen or C1-4-alkyl. The invention also relates to a method of preparing the compounds, pharmaceutical compositions thereof, and their use. The compounds are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters, particularly the quisqualate receptors, and especially as neuroleptics.
Patent PT-97562-A (PT)
Inventor: MAROTEAUX ISABELLE
IPC: A61K9/24
Filed: 1991-05-03
Abstract: A pharmaceutical composition including a core of an NSAID selected from diclofenac and piroxicam which core is surrounded by a mantle coating of a prostaglandin, wherein an intermediate coating can be present between the NSAID core and prostaglandin mantle coating.
Patent SI-9300206-A (SI)
Inventor: PROSEK MIRKO
IPC: G01N30/60
Filed: 1993-04-20
Abstract: Kolona je značilna po tem, da ima vzdolž osi Separacijska kolona omogoča hitrejšo ločbo, boljšo
zvezno spreminjajoč notranji premer, ki se bodisi veča ločljivost in do 50% boljšo kapacitivnost pikov,
Patent SI-9600033-A (SI)
Title: Substituted tiophensulfonyl ureas and thioureas, process for the preparation thereof, use thereof as medicine or as diagnostic as well as medicine containing them
Inventor: ENGLERT HEINRICH
IPC: C07D333/34
Filed: 1996-02-01
Abstract: N-((2-Benzamidoethyl)- thiophene-sulphonyl)-urea or-thiourea derivs. of formula (I) are new. R1 = H, halogen, Me, Et, OMe, OEt, SMe, SEt, 1-2C fluoroalkyl or 1-2C fluoroalkoxy; X = O or S; R2 = H, Me or CF3; Y, Z = H, F, Cl, Br, I, Me, Et, OMe or OEt.
Patent UA-13234-A (UA)
Title: High-resistivity material for precision thin-film resistors
Filed: 1990-03-21
Abstract: The high-resistivity material for precision thin-film resistors comprises yttrium, chrome and silicon. It is made as yttrium, chrome and silicon alloy.
Patent BG-100686-A (BG)
Title: Use of dimeticone for treating constipation
Inventor: SCHMIDT ALFRED
IPC: A61K31/80
Filed: 1996-07-01
Abstract: The invention disclosed relates to the use of dimeticone as an agent for treating constipation.
Patent BG-103535-A (BG)
Title: System for electric power supply of a moving object
Inventor: GEORGIEV GEORGI S
IPC: B60L5/34
Filed: 1999-06-28
Abstract: The system can be applied in electric power supply of transport vehicles using electric traction. By it easy and fast overtaking, bypassing and U-turning of the vehicle is made. The system consists of contact bands (1-8) and insulation bands (9-15). The contact bands of even numbers are connected to one of the poles, and the contact bands of uneven numbers to the other pole. The contact device is mounted on the transport vehicle and comprises of an insulation base (16), contact brushes(17, 18, 19, 20) and brush-holders. 4 claims, 3 figures
Patent BG-105849-A (BG)
Title: Process for the recovery of acrylonitrile and methacrylonitrile
Inventor: HAGANS MICHAEL K
IPC: B01D3/14
Filed: 2001-08-27
Abstract: The process of manufacturing an unsaturated mononitrile selected from the group consisting of acrylonitrile and methacrlonitrile comprising transporting a reactor effluent containing the unsaturated mononitrile to a first column where the reactor effluent is cooled with at least one aqueous stream, transporting the cooled effluent containing the unsaturated mononitrile into a second column where the cooled effluent is contacted with at least one second aqueous stream to absorb the unsaturated mononitrile into at least one second aqueous stream, transporting the second aqueous stream containing the unsaturated mononitrile from the second column to a first distillation column for separation of the crude unsaturated mononitrile from the second aqueous stream, and transporting the separated crude unsaturated mononitrile to a second distillation column to remove at least some impurities from the crude mononitrile, and transporting the partially purified crude unsaturated mononitrile to a third distillation column (product column) to further purify the crude unsaturated mononitrile, recovering the purified unsaturated mononitrile as a side stream from the product column, introducing about 100 to about 2000 ppm of water in the form consisting of steam and distilled water into the bottom stream obtained from the product column and recycling at least part of the product bottom stream obtained from the product column to the bottom portion of the product column. In another aspect of the present invention the stream and distilled water is added directly to the product column. 18 claims, 1 figure
Patent BG-106734-A (BG)
Inventor: BRYANT HELEN J
IPC: C07D519/00
Filed: 2002-05-22
Abstract: Изобретението се отнася до съединения или до техни соли с формула, в която R1 означава халоген или С1-6 алкил, С3-7 циклоалкил, С4-7 циклоалкенил, С6-8 бициклоалкил, С6-10 арил, С3-7 хетероциклоалкил, хетероарил, или ди(С1-6)алкиламино, като всяка от тези групи може да е по избор заместена; L е О, S или NRn, където Rn е Н, С1-6 алкил или С3-6 циклоалкилалкил; W е С1-6 алкил, С2-6 алкенил или С2-6алкинил, заместени по избор; Х е NR4R5 или пет- или шестчленен хетероароматен пръстен, като пет- илишестчленният хетероароматен пръстен по избор е кондензиран към бензенов или пиридинов пръстен и хетероароматният пръстен е заместен по избор; Y е по избор разклонен С1-4 алкилен, заместен по избор с оксогрупа, или Y е група (СН2)jO, където кислородният атом е най-близкият до групата Х, j има стойност 2, 3 или 4; Z означава пет- или шестчленен хетероароматен пръстен, като който и да е от тези пръстени може да е заместен по избор. Изобретението сеотнася и до фармацевтични състави, които съдържатсъединенията, до използването им в методи за лечение и в производството на лекарства за усилване накогнитивната способност, по-специално при лечениена болестта на Алцхаймер, както и до съответнитеметоди за лечение. Съединенията са лиганди и инверсни агонисти на GABAA алфа 5 рецепторен подтип.
Patent BG-108130-A (BG)
Title: N-phenpropylcyclopentyl-substituted glutaramide derivatives as nep inhibitors for fsad
Inventor: CHALLENGER STEPHEN
IPC: A61K31/353
Filed: 2003-08-25
Abstract: The invention relates to compounds of formula for treating for example sexual dysfunction, wherein R1 is optionally substituted C1-6 alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, hydrogen, C1-6 alkoxy, -NR2R3 or -NR4SO2R5; X is the linkage -(CH2)n- or -(CH2)q-O- (wherein Y is attached to oxygen); wherein one or more hydrogen atoms in linkage X may be replaced independently by C1-4 alkoxy; hydroxy; hydroxy (C1-3 alkyl); C3-7 cycloalkyl; carbocyclyl; heterocyclyl; or by C1-4 alkyl optionally substituted by one or more fluoro or phenyl groups; n is 3, 4, 5, 6 or 7; and q is 2, 3, 4, 5 or 6; and Y is phenyl or pyridyl, each of which may be substituted; or two R8 groups of adjacent carbon atoms together with the interconnecting carbon atoms may form a fused optionally substituted 5- or 6-membered carbocyclic or heterocyclic ring. 28 claims, 2 figures
Patent CN-1328366-A (CN)
Title: 脉冲气体激光器
Inventor: WAN ZHONGYI
IPC: H01S3/03
Filed: 2000-06-13
Abstract: 一种脉冲气体激光器,包括主放电电极,全反射端镜和输出耦合镜,其中两个主放电电极为相对设置;在主放电电极的两侧与主放电电极相隔预定距离,分别排列有两印刷电路板预电离器,该两印刷电路板预电离器分别与两个主放电电极相连接;本发明结构简单,性能可靠,适用于各种脉冲气体激光器。
Patent CN-1305077-A (CN)
Title: 控制加热或冷却循环水温度的人工智能系统及方法
Inventor: SANG-UN LO
IPC: F24F11/02
Filed: 2000-12-11
Abstract: 本发明提供用于控制循环水温度的人工智能系统和方法,利用电子温度传感器和MPU(微处理器)快速准确测量热水的温度,使房间温度保持恒定,使用户拥有舒适的环境。该系统与一个通信装置例如电话、调制解调器和个人计算机结合,通过使循环水调节阀与MPU直接通信,可进行外部遥控和中央控制,避免了布线工作,降低了工作时间。因此,系统的制造成本大大降低,并为用户提供了更大的方便。
Patent CN-1381894-A (CN)
Title: 互补双极晶体管及其制造方法
Inventor: CHUNG-BAE KIM
IPC: H01L27/082
Filed: 2002-02-21
Abstract: 有横向npn双极晶体管,垂直和横向pnp双极晶体管,集成注入逻辑,扩散电容器、多晶硅电容器和多晶硅电阻器的互补双极晶体管。横向双极晶体管有包括高浓度区和低浓度区的发射区和集电区,发射区形成在n型桶形区中。集成注入逻辑电路中,集电区由高浓度p型区包围,低浓度p型区形成在集电区下面。一个衬底中形成扩散电容器和多晶硅电容器。扩散区在形成多晶硅电阻器之前,除了把多晶硅电阻器中的杂质扩散进外延层中形成的区域之外,还形成沿多晶硅电阻器的多晶硅电极。
Patent CN-1508581-A (CN)
Inventor: ZHANG SHAOXIONG
IPC: G02B6/132
Filed: 2002-12-17
Abstract: 一种微机电式法布里－珀罗装置制造方法，包含如下步骤：提供二不同基材，并以薄膜沉积方法于该基材表面的预定区域形成沉积物，再结合该沉积物间隔该不同基材。于进行薄膜沉积时以一膜厚监控器精确控制该沉积物的厚度，使介于二基材中间的沉积物的厚度等于该法布里－珀罗装置的所需间距。
Patent CN-1550022-A (CN)
Inventor: GIORGIO LONGONI
IPC: H01J7/18
Filed: 2002-11-11
Abstract: 本发明涉及一种在真空操作的系统内部进行钙蒸发的方法。该方法包括以下步骤：向所述系统内引入至少一种可蒸发吸气器，该可蒸发吸气器包含有空气稳定钙化合物；开始抽空该系统，直至到达压力值P 1 ；加热(R)可蒸发吸气器，直至所述稳定化合物到达钙蒸发温度；继续抽空该系统，直至到达小于P 1 的压力值P 2 ；密封该系统(S)。
Patent CN-1555368-A (CN)
Inventor: NORMAN HERRON
IPC: C07D307/46
Filed: 2002-09-17
Abstract: 本发明涉及利用钒催化剂在单一溶剂体系中由果糖源制备2，5－二甲酰呋喃的单罐装的二步法。本发明是一种制备2，5－二甲酰呋喃的方法，其包括步骤：a)将碳水化合物源与第一溶剂混合；b)在足以形成2，5－羟甲基糠醛的温度下加热步骤a)中的反应混合物；c)在步骤b)的反应混合物中加入氧化剂和催化剂量的钒化合物；以及d)在足以形成2，5－二甲酰呋喃的温度下加热步骤c)中的反应混合物；在步骤b)、c)或d)之后无需加入附加的溶剂。
Patent CN-1585939-A (CN)
Title: 利用数据导引对数据进行计算和操作的方法和装置
Inventor: GOVIND KIZHEPAT
IPC: G06F9/30
Filed: 2002-08-05
Abstract: 一种基于硬件引擎的数据处理系统，包括多个功能单元(10)和与所述功能单元互联的数据路由单元(20)。硬件引擎在数据在软件的控制下遍历经过功能单元的通路时对数据进行计算。功能单元包括逻辑源，其示例为触发器、锁存器、算术逻辑单元、随机存取存储器等。路由单元响应于被接通或断开的软件控制信号，来导引数据经过这些源。根据导引数据(30)经过功能单元来完成操作和计算，而不是根据在现有技术中典型的对控制功能的执行的操作命令进行解码来完成操作和计算。
Patent CN-1633807-A (CN)
Inventor: GEORGES BUCHNER
IPC: H04N7/15
Filed: 2002-11-12
Abstract: 本发明涉及一种将本地场景和远程场景集合在一起的模块化视听系统。本发明特征在于该系统包括：几个串联的视听模块(M1，M2，M3)，每个模块包括用于本地场景的一个图像感测设备和一个拾音装置，和在图像平面(I)内用于复原远程场景的图像和声音的装置，该模块被连接到一个传输网络；在各个模块之间的自动控制和监控装置(P)以确保当正在被拍摄和录制的人从有关的场景的各种图像和拾音装置的前面经过时在图像平面上的图像和声音质量的连续性。
Patent CN-1429804-A (CN)
Title: 山梨酸的制备方法
Inventor: MOELENKOPUF C
IPC: C07C59/245
Filed: 2003-01-03
Abstract: 一种制备山梨酸的方法，该方法在溶剂和作为催化剂的胺存在时，通过热裂解由巴豆醛和乙烯酮制备的聚酯，同时通过带有回流的精馏塔馏出所形成的山梨酸及溶剂来进行，其中只使用溶剂而不是馏出液作为回流，导致高的山梨酸收率以及降低了的胺催化剂的消耗量。
Patent CN-1443896-A (CN)
Title: 钢制帘线及其制造方法以及含有该钢制帘线的充气轮胎
Inventor: SHINICHI MIYASAKI
IPC: B60C9/20
Filed: 2003-03-12
Abstract: 一种钢制帘线由3～6根钢制单丝构成，每根单丝具有在0.25～0.45mm范围内的单丝直径，该3～6根钢制单丝包括成形单丝且被捻合在一起，其中成形单丝在捻合之前卷绕成具有线圈直径小于5mm和线圈节距大于5mm的线圈的形式，成形单丝包括至少两种卷绕形式不同的成形单丝，线圈直径变小的同时成形单丝被捻合在一起，帘线的伸长在50N负荷时小于0.2％和帘线强度在范围2500～3500N/mm 2 。
Patent CN-1497531-A (CN)
Inventor: ATSUSHI SHIMANO
IPC: G10C1/04
Filed: 2003-09-29
Abstract: 一种键盘盖止动装置(20，30)设置用于诸如大钢琴的键盘乐器，所述大钢琴配备有打开或关闭到布置在键床(2)上的琴键上的键盘盖(1)。所述键盘盖止动装置基本上包括相互分离的第一止动件(21，31)和第二止动件(31，32)，所述止动件分别安装在键盘乐器的规定部分(诸如侧板(8)的内壁)和安装在键盘盖的后端部分的规定位置上。第一止动件具有在键盘盖打开时与第二止动件接合的接合部分(23，33)，由此在键盘盖打开时键盘盖能借助第一和第二止动件之间建立起的机械接合而可靠地停止在正确的位置上。
Patent CN-1450360-A (CN)
Title: 移动目标全球定位监控装置
Inventor: ZHANG YUE
IPC: H04W88/02
Filed: 2003-04-25
Abstract: 本发明涉及一种移动目标全球定位监控装置，属移动目标全球定位和监控技术领域。该装置包括主机部分和手柄部分，其中的主机部分包括信号接收电路、加密压缩处理器、无线通讯电路、主控处理器、液晶显示屏、显示处理器和电源；其中的手柄部分包括：信息输入输出装置、输入处理器；上述输入处理器、主控处理器、加密压缩处理器和显示处理器之间由时钟线和数据线相连。本发明提出的移动目标全球定位及监控装置，其优点是定位精度高，使用范围广，功能强大反应快，保密性、可靠性高。
Patent CN-1492028-A (CN)
Inventor: HU JINXIAN
IPC: C10L3/00
Filed: 2003-09-20
Abstract: 一种灶罐通用型复合二甲醚液化气，它由二甲醚、石油液化气及添加剂组成，各组份所含重量百分比是：二甲醚35－70％、石油液化气30－50％，添加剂10－20％。本发明最大的优点是：所配制的燃料无需用专配套灶具燃烧，而是与目前市场上普遍使用的石油液化气标准炉灶燃烧和钢瓶储放，这就大大地有利于推广应用。
Patent CN-1682302-A (CN)
Inventor: STUART BUTTERFIELD
IPC: G11C7/16
Filed: 2003-08-29
Abstract: 本发明包括一种信息记录装置(1)，其包括具有限定数量的存储空间的存储器设备(3)，和由用户启动将数据记录到该存储器设备(3)上时使用的接口(2)，其中该存储器设备(3)的被选择的部分存储空间是为在紧急情况下记录数据而保留的，并且该接口(2)被这样设计，使得用于将数据记录到该存储器设备的被选择的部分中的指令由装置实施，该装置与那些被用于启动在该存储器设备的剩余部分中记录数据的装置分离。
Patent CN-88100326-A (CN)
IPC: F04C28/00
Filed: 1988-01-19
Abstract: 本发明涉及的密封型旋转式压缩机，关闭和开启汽缸压缩室内被压缩致冷气体的排出口的旋转体与转子成为一体，排出阀在开启之前旋转体挡住开口，排出阀开启时，使排出阀的反压力暂时下降，以使排出阀的开启动作平滑进行。
Patent CN-1034088-A (CN)
Inventor: MU HE
IPC: H01B12/00
Filed: 1988-12-23
Abstract: 本发明是铌管富锡法制备Nb 3 Sn高场导体方法
的改进，属于超导导体的加工工艺，本发明通过同时
将第三元素Ti和第四元素Mg加入到Nb材和母材
中，明显改善了Nb 3 Sn导体在0-20特拉斯整个实用
磁场范围的载流能力。
Patent CN-1037299-A (CN)
Inventor: OHARA OSAMU
IPC: B27N3/04
Filed: 1988-09-05
Abstract: 一种高粱秆层压板，它至少包含两层整体粘结的
高粱秆层，高粱秆未经劈开并保留秆芯部分；以及它
的制作方法。按照本发明层压高粱秆板具有可在大
范围内变化的比重，良好的保温和吸音特性和提高了
的机械强度，并可以用简单的生产方法进行生产。
Patent CN-1104861-A (CN)
Title: 花粉破壁与营养成分提取技术
Inventor: SHIXIU LU
IPC: A23L21/20
Filed: 1993-04-17
Abstract: 本发明是一种花粉破壁与营养成分提取技术，是
将花粉通过物理方法破壁，再经离心过滤处理提取精
制花粉营养液。全过程是在较低的环境下进行，具有
破壁完全的优点，同时能达到灭菌和澄清的效果。其
花粉营养液呈浅黄色，清晰透明，有其独特香味，营养
丰富，易被人体吸收，利用，是一种纯天然营养食品。
Patent CN-1095107-A (CN)
Title: 盐藻β-胡萝卜素增产素
Inventor: JIANGUO LIU
IPC: C12P23/00
Filed: 1993-05-09
Abstract: 本发明属养殖盐藻生产β-胡萝卜素生物技术领
域。 
     目前养殖盐藻周期较长，相对限制β-胡萝卜素
的产量。寻找盐藻β-胡萝卜素增产素成为该领域的
关键之关键技术问题。 
     为解决这一技术问题，本发明的构思是：从盐藻
生物学和β-胡萝卜素累积的生理生态学角度分析总
结，提出外加调节盐藻生长和β-胡萝卜素累积的增
产素，促进β-胡萝卜素累积，提高产量。
Patent CN-1089361-A (CN)
Inventor: YINQI GUO
IPC: H01J43/04
Filed: 1993-10-21
Abstract: 一种制作小尺寸微通道板的方法，其特点是将玻

璃丝束在玻璃管内作有序排列，方法简单、可靠，所制

得的微通道板其孔形规正、排列有序、分布均匀，能大

大提高生产效率和产品质量，降低生产成本。
Patent CN-1115104-A (CN)
Inventor: OH SEUNG-CHEOL
IPC: G11C11/407
Filed: 1994-11-18
Abstract: 一种用于具有一个存储单元阵列的半导体存储器件的行冗余电路，在所说存储单元阵列两侧形成的第一和第二主行解码器及第一和第二备用行解码器包括：接收地址用的第一、第二熔丝盒，并在接收地址中出现有缺陷地址时熔断有缺陷地址的输入通路上的熔丝，从而向第一、第二备用行解码器提供输出信号；及接收第一和第二熔丝盒的输出信号用的行冗余控制电路，响应接收输入信号电平向第一和第二备用行解码器选择性地提供输出信号。
Patent CN-1136350-A (CN)
Title: 空调机
Inventor: TOMOMI UMEDA
IPC: F25B41/06
Filed: 1995-10-05
Abstract: 本发明的目的在于降低在除湿运转时在除湿节流装置中产生的制冷剂流动音。将使用侧的热交换器3分成2部分，设置成在其间设置了在除湿运转时使用的除湿节流装置7的冷冻循环，作为除湿节流装置7，设置在阀棒34和阀座36之间形成的主制冷剂通路27、和另一路连结高压侧的制冷剂流路32和低压侧的制冷剂流路28的副制冷剂通路25，利用阀棒34将其副制冷剂通路25的一部分设置在阀棒34内。
Patent CN-1148697-A (CN)
Inventor: TAKASHI NAKACHI
IPC: H04N9/64
Filed: 1996-07-27
Abstract: 在视频信号处理装置中将试验图形视频信号V0转换成8位数据，并与写入控制电路5中产生的取样时钟同步，然后存储在存储器中。MPU9读出该视频信号的有效区域中的象素数据，并计算其值大于预定值的白电平象素数据的平均值和小于预定值的黑电平象素数据的平均值之间的差AT，以及白电平象素数据和黑电平象素数据之间的总变化VT。MPU9控制在写入控制电路5中产生的取样时钟的相位使AT为最大而VT为最小。
Patent CN-1258299-A (CN)
Title: 多环红霉素衍生物
Inventor: OR Y S
IPC: A61K31/7048
Filed: 1998-05-22
Abstract: 本发明公开了新的具有抗菌活性的式(Ⅰ)、(Ⅱ)、(Ⅲ)、(Ⅳ)、(Ⅴ)、(Ⅵ)、(Ⅶ)、(Ⅷ)、(Ⅸ)、(Ⅹ)或(Ⅺ)的多环红霉素化合物及其可药用的盐或酯,含有治疗有效量的本发明化合物和可药用的载体的药物组合物,以及一种治疗细菌感染的方法,包括给哺乳动物施用含有治疗有效量的式(Ⅰ)化合物的药物组合物。
Patent CN-1299438-A (CN)
Title: 尤其用于柴油机或稀混合气发动机的催化转换器
Inventor: BRUECK ROLF
IPC: F01N3/28
Filed: 1999-05-03
Abstract: 本发明涉及一种净化内燃机尤其柴油机或稀混合气发动机废气的催化转换器,包括至少一个有催化活性物质涂层的蜂窝体(6),它有通过壁(4、5)互相分开可流过废气的通道(3),其中,转换器沿流动方向(S)前后有第一区(1)和第二区(2),其中第一区(1)蜂窝体(6)每单位体积的热容量比第二区(2)的小,其特征在于,第二区(2)的热容量至少有每升和每开尔文800焦耳[J/LK],优选地至少有900。优选地,金属薄板层(4、5)在第一区(1)内平均无涂层的厚度小于0.06mm,优选地小于0.04mm,以及在第二区内平均无涂层的厚度大于0.06mm,优选地大于0.08mm,尤其有0.11mm厚。以此方式。第一区(1)当排气温度高时可迅速达到工作温度,而在此期间第二区(2)可以蓄热用于排气温度低的工作状态。
Patent CN-1344476-A (CN)
Title: 无线电通信系统中的用户组指示与状态变化
Inventor: RAITH A K
IPC: H04W68/02
Filed: 1999-11-16
Abstract: 本发明提供使用广播或点对点无线电通信资源来给移动站用户提供信息的组呼业务。首先,发送已存在有组呼的指示给移动站。随后,提醒移动站的用户存在有相关的组呼,即,他们适合参与的那些呼叫。
Patent CR-20150363-A (CR)
Title: Combinación de un medicamento que comprende fenilefrina y paracetamol
Inventor: ATKINSON HARTLEY CAMPBELL
IPC: A61P11/12
Filed: 2015-07-09
Abstract: El uso del hidrocloruro de fenilefrina (o una cantidad equivalente de una forma alternativa farmacéuticamente aceptable de fenilefrina) y paracetamol en la producción de un medicamento combinado para el tratamiento de la congestión de las mucosas de las vías respiratorias superiores, medicamento que comprende la combinación de tales sustancias con excipientes.
Patent CR-20170205-A (CR)
Title: Composición para el tratamiento de ectoparasitosis y la promoción del crecimiento en acuicultura
Inventor: LOZANO-DUBERNARD BERNARDO
IPC: A61K31/132
Filed: 2014-10-20
Abstract: Composición para acuicultura, caracterizada que comprende por lo menos un compuesto protector externo de especies acuáticas, solo o en combinación con otros compuestos o excipientes. Igualmente, se describe una composición de alimento para acuicultura. Ambas composiciones son útiles en el tratamiento seguro y eficaz de ectoparasitosis en acuicultura, así como en la promoción del crecimiento en acuicultura.
Patent CR-20190008-A (CR)
Title: Sensores que tienen circuitería de protección integrada
Inventor: KWOK LISA
IPC: G01N35/00
Filed: 2018-04-19
Abstract: Un sensor de ejemplo incluye una celda de flujo, un dispositivo de detección y un controlador. La celda de flujo incluye una capa de pasivación que tiene superficies opuestas y un sitio de reacción en una primera de las superficies opuestas. La celda de flujo también incluye una tapa conectada de manera operativa a la capa de pasivación para definir parcialmente un canal de flujo entre la tapa y el sitio de reacción. El dispositivo de detección está en contacto con una segunda de las superficies opuestas de la capa de pasivación, e incluye una capa metálica incrustada que está aislada eléctricamente de otra circuitería de detección del dispositivo de detección. El controlador es para conectar a tierra la capa metálica incrustada.
Patent CR-20190388-A (CR)
Title: Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
Inventor: PEPER JANET
IPC: C07K14/705
Filed: 2018-01-26
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor- associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.La presente invención se refiere a péptidos, proteínas, ácidos nucleicos y células destinados a la utilización en métodos inmunoterapéuticos. En particular, la presente invención se refiere a la inmunoterapia contra el cáncer. La presente invención se refiere asimismo a epítopos peptídicos para linfocitos T asociados a tumores, solos o en combinación con otros péptidos asociados a tumores que, por ejemplo, pueden servir como principios activos farmacéuticos en composiciones vacunales destinadas a estimular respuestas inmunitarias antitumorales, o a estimular ex vivo linfocitos T que después serán transferidos a los pacientes. Los péptidos unidos a moléculas del complejo mayor de histocompatibilidad (MHC), o los péptidos como tales, también pueden ser dianas de anticuerpos, de receptores de linfocitos T solubles, y de otras moléculas de unión.
Patent CR-20200227-A (CR)
Title: Native valve repair devices and procedures
Inventor: TYLER GREGORY SCOTT II
IPC: A61F2/24
Filed: 2019-01-08
Abstract: <p>A valve repair device for repairing a native valve of a patient includes a pair of paddles, a pair of gripping members, and a spacer element. The paddles are movable between an open position and a closed position. The paddles and the gripping members are configured to attach to the native valve of the patient. The spacer element is configured to close a gap in the native valve of the patient when the valve repair device is attached to the native valve.</p>
Patent CR-20200353-A (CR)
Title: Thixotropic antimicrobial composition
Inventor: PERRY LINDSEY
IPC: A61K47/10
Filed: 2019-02-15
Abstract: <p>A thixotropic antimicrobial composition includes a thixotropic agent and an antimicrobial agent. The thixotropic antimicrobial composition may be used to treat various food products or surfaces. Some thixotropic antimicrobial compositions may include peroxyacetic acid as an antimicrobial agent and/or xanthan gum or guar gum as a thixotropic agent. A treated article may include the thixotropic antimicrobial composition on at least one surface thereof.</p>
Patent EC-SP056117-A (EC)
Title: Ligandos de receptores de cannabinoides y sus usos
Inventor: DOW Robert
IPC: A61K31/4745
Filed: 2005-10-21
Abstract: En la presente, se describen compuestos de fórmula (I) y (II) que actúan como ligandos de receptores de cannabinoides, y sus usos en el tratamiento de enfermedades conectadas con la mediación de receptores de cannabinoides en animales.
Patent EC-SP088322-A (EC)
Title: Derivados de fenil-1,2,4-oxadiazolona, procesos para su preparación y su uso como compuestos farmacéuticos
Inventor: BERNARDELLI PATRICK
IPC: A61K31/4245
Filed: 2008-03-27
Abstract: La invención se refiere a derivados de fenil-1,2,4-oxadiazolona en todas sus formas estereoisoméricas y mezclas en cualquier relación, y sus sales fisiológicamente aceptables y formas tautoméricas que muestran actividad agonista de PPARdelta. Lo que se describe son compuestos de la fórmula I,								(I) donde los radicales son como se han definido, y sus sales fisiológicamente aceptables y procesos para su preparación. Los compuestos son adecuados para el tratamiento y/o prevención de trastornos de metabolismo de ácidos grasos y trastornos de utilización de la glucosa así como de trastornos en los que está implicada la resistencia a la insulina y la desmielinización y otros trastornos neurodegenerativos del sistema nervioso central y periférico.
Patent EC-SP910722-A (EC)
Title: Mejoramiento de la fermentacion de cacao
Inventor: BANGERTER ULRICH
IPC: A23G1/30
Filed: 1991-02-08
Abstract: El método de la presente invención se refiere a un pretratamiento de granos de cacao frescos para reducir la cantidad de pulpa, a efectos de que la fermentación subsiguiente se realice en condiciones altamente aeróbicas, favoreciendo la actividad de las bacterias de ácido acético sobre las de ácido láctico; con lo cual pH permanece sobre 5 y los resultados son un cacao con sabor mejorado.