baber/WOPTO huggingface dataset:
Patent AU-2021217373-A1 (AU)
Title: Method of treating a solid tumor with a combination of an IL-7 protein and CAR-bearing immune cells
Inventor: DIPERSIO JOHN F
IPC: A61P35/00
Filed: 2021-02-04
Abstract: The present disclosure relates to methods of treating a solid tumor with an IL-7 protein in combination with a population of modified immune cells, e.g, CAR-bearing immune cells (e.g., CAR-T cells or iNKT-CAR cells) and/or transgenic TCR-bearing immune cells.
Patent AU-2021249531-A1 (AU)
Title: Vectors for producing virus-like particles and uses thereof
Inventor: SLAVCEV RODERICK
IPC: C07K14/165
Filed: 2021-03-31
Abstract: The present disclosure provides expression vectors and bacterial sequence-free vectors, such as ministring DNA (msDNA), for producing virus-like particles (VLPs) as well as compositions and methods thereof. In some aspects, the methods include treating viral infections in subjects with the vectors, compositions, and VLPs.
Patent AU-2021282499-A1 (AU)
Title: Isolated polynucleotides and polypeptides, and methods of using same for increasing nitrogen use efficiency, yield, growth rate, vigor, biomass, oil content, and/or abiotic stress tolerance
Inventor: PANIK DAVID
IPC: A01H1/06
Filed: 2021-12-09
Abstract: Provided are isolated polynucleotides and nucleic acid constructs which comprise a nucleic acid 
sequence at least 80 % identical to a nucleic acid sequence selected form the group consisting 
of SEQ ID NOs: 277, 1-276, 278-469 and 785-2397; and isolated polypeptides which comprise 
an amino acid sequence at least 80 % homologous to an amino acid sequence selected from the 
group consisting of SEQ ID NOs: 482, 470-481, 483-784 and 2398-3818. Also provided are 
transgenic cells and plants expressing same and methods of using same for increasing nitrogen 
use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, and/or 
abiotic stress tolerance of a plant.
Patent AU-2021292577-A1 (AU)
Title: Boom mounted spray nozzle assembly with compact multi spray nozzle design
Inventor: PRICE TREVOR
IPC: B05B1/16
Filed: 2021-06-18
Abstract: A liquid spray boom for supporting a plurality of spray nozzle assemblies each having a compact design that enables transfer and storage of the spray boom with lesser tendency for damage. The spray nozzle assemblies each include a liquid inlet section and a pair of spray nozzle liquid supply and support legs extending from the liquid inlet section in forward transverse relation to the spray boom and at an acute angle to each other. A spray nozzle is removably mounted on each nozzle body liquid supply leg with a respective check valve disposed in rearward relation to the spray nozzle. The liquid inlet section, Y body, and supporting components for the spray nozzles and check valve are adapted for quick disconnect assembly and disassembly.
Patent AU-2021314320-A1 (AU)
Title: Systems and methods of a transition and notification protocol
Inventor: BROOKS MICHAEL
IPC: H04M3/00
Filed: 2021-07-23
Abstract: Systems, devices, and methods including a computing device (120) with a processor (124) configured to: send a keep-alive signal to a user at a predefined interval (302); determine an active status of the user if a reply to the keep-alive signal is received prior to an expiration of the predefined interval (304); determine a non¬ active status of the user if a reply to the keep-alive signal is not received prior to an expiration of the predefined interval (304); send a first level transition notification to a first contact list if the determined status of the user is non-active (306); send a second level transition notification to a second contact list after a first time period has expired and the reply to the keep-alive signal is not received (308); and send a third level transition notification to a third contact list after a second time period has expired and the reply to the keep-alive signal is not received (310).
Patent AU-2021349932-A1 (AU)
Title: Mounting pocket for remote equipment monitoring device
Inventor: LINDEMAN ADAM
IPC: F04D29/40
Filed: 2021-09-15
Abstract: A mounting pocket is provided for attaching a monitoring device to a pump bearing frame. The mounting pocket includes a recessed area located on an external side of the pump bearing frame, a flat surface within the recessed area; and at least four threaded mounting holes extending into the flat surface. At least a part of the drive bearing portion has a reduced radial wall thickness adjacent the flat surface. The threaded mounting holes are configured to receive threaded bolts from the monitoring device to secure the flat surface against a rear surface of the monitoring device. The flat surface is configured to transfer at least one of vibration or thermal energy from the pump bearing frame through the flat surface to the monitoring device.
Patent AU-2021351756-A1 (AU)
Title: Axle-end electricity generating apparatus and bogie of railway car
Inventor: LI ZHIZE
IPC: B61F1/10
Filed: 2021-07-12
Abstract: An axle-end electricity generating apparatus and a bogie of a railway car. The apparatus comprises a supporting saddle, a mounting frame, and an electric generator. The electric generator comprises a stator, a rotor, and a housing. The stator is mounted in the housing. The rotor is mounted at an axle end of a vehicle axle. The supporting saddle is provided at the bottom surface thereof with an arced mounting surface fitting a bearing. The mounting frame is provided on the upper end surface with a notch to accommodate a part of the bearing. The supporting saddle and the mounting frame are joined to form an annular outer end surface. The annular outer end surface is provided with a mounting structure used for being fittingly fixed to the housing. When such structure is employed, the supporting saddle and the mounting frame are joined to form an annular structure, which can be fixed on the bearing, at the same time, the annular outer end surface used for mounting the housing is formed on the side, a complete mounting structure for mounting the electric generator is provided, and, when mounting, only the mounting frame needs to be mounted below the supporting saddle to complete the process, thus increasing the convenience of mounting.
Patent AU-2021401165-A1 (AU)
Title: Tail cutter for saving and partly cutting free tails of slaughtered animals
Inventor: GOLDEWIJK RICHARD ANTONIUS MARIA KLEIN
IPC: A22B5/20
Filed: 2021-12-17
Abstract: A tail cutter or tail saver capable of partly cutting free the tail of an animal carcass while the cutting device is cutting the back of an animal carcass into two halves. The tail saver is suitable for being connected to a cutting device for splitting animal carcasses. The tail cutter comprises a tail knife with a longitudinal cutting blade for cutting free part of the tail at the base part of the tail, a finger connected to the tail knife, the finger being capable of directing the loose part of the tail to a predetermined side of the animal carcass, the finger is bent to the right or left relative to the longitudinal direction of the cutting blade of the tail knife, and the cutting blade of the tail knife is located in line with and/or in the same plane as the cutting device when the tail knife is located on this cutting device.
Patent AU-2021441304-A1 (AU)
Title: Mine hoist monitoring system
Inventor: KENT-RODGMAN CHRISTOPHER
IPC: B66B5/00
Filed: 2021-04-19
Abstract: A mine hoist monitoring system (102) for monitoring a mine hoist (100) comprising a hoist drum (120), the mine hoist monitoring system (102) comprising a hoist controller (150) configured for controlling the mine hoist (100); a plurality of strain gauges (144) mounted on the hoist drum (120); and at least one drum data node (140) mounted on, the hoist drum (120), the plurality of strain gauges (144) being coupled to the at least one drum data node (140), wherein the at least one drum data node (140) is configured for determining strain signals indicative of strain in the hoist drum (120) using the plurality of strain, gauges (144); wherein the at least one drum data node (140) is configured for transmitting the strain signals to the hoist controller (150); wherein the hoist controller (150) is configured for determining a strain, distribution, in the hoist drum (120) based, on the strain signals received from the at least one drum data node (140), and wherein the hoist controller (150) is configured for visualizing the strain distribution.
Patent WO-2023245224-A1 (WO)
Title: Collier
Inventor: WATSON KEVIN JASON
IPC: F21V21/04
Filed: 2022-06-20
Abstract: Un collier pour retenir un luminaire dans un panneau, le collier ayant un rebord définissant une ouverture, le rebord ayant une première extrémité et une seconde extrémité, la première extrémité et la seconde extrémité du rebord définissant un espace dans le rebord, et une pluralité de parties de bride s'étendant vers l'extérieur à partir du rebord, chaque partie de bride étant espacée d'une partie de bride adjacente, le rebord étant souple de telle sorte que le diamètre du rebord est réglable.
Patent AU-2022200331-A1 (AU)
Title: Phosphorus prodrugs of sGC stimulators
Inventor: SHEPPECK JAMES EDWARD
IPC: C07F9/09
Filed: 2022-01-19
Abstract: The present patent application discloses the compounds according to Formula I shown 
below, or pharmaceutically acceptable salts thereof, wherein JB, n, R, R 2, R 3, R4 , Rim and X as 
defined herein.  
___(JB)n 
N N 
'N 
N R 4 R4 -(CH 20)m-X 
N N R2 
R3 
Formula I
Patent AU-2022201107-A1 (AU)
Title: Methods and systems for capturing biometric data
Inventor: WHITE CONOR ROBERT
IPC: G06V10/12
Filed: 2022-02-18
Abstract: OF THE DISCLOSURE 
A method of capturing biometric data is provided that includes calculating, by a terminal 
device, an angle between a surface of the terminal device and an X-axis of the terminal device.  
When the angle is other than ninety degrees, a prompt is displayed on the terminal device that is 
designed to cause a terminal device user to adjust the position of the terminal device into an 
optimal position. After adjusting the position of the terminal device, the terminal device calculates 
the angle and when the angle is ninety degrees the terminal device captures biometric data from the 
user.
Patent AU-2022201818-A1 (AU)
Title: Implantable ocular drug delivery devices
Inventor: CAMPBELL RANDOLPH E
IPC: A61F9/00
Filed: 2022-03-16
Abstract: Described are implantable devices having reservoirs for the sustained release of 
therapeutic agents. The devices are configured to be at least partially implanted in an eye and 
include a retention structure and a penetrable element coupled to and extending within at least 
a portion of the proximal end region of the device. The device includes a porous drug release 
element is positioned in fluid communication with an outlet of the device and a reservoir 
having a volume configured to contain one or more therapeutic agents in fluid 
communication with the outlet through the porous drug release element. The device is at 
least partially inserted along an axis of insertion.
Patent AU-2022202231-A1 (AU)
Title: Syringe with disinfecting feature
Inventor: LEIBOWITZ EVAN
IPC: A61M5/31
Filed: 2022-04-01
Abstract: This invention relates to syringe assemblies comprising an absorbent pad containing disinfectant and a 
rotatable cap to ensure adherence to aseptic techniques for use in flush procedures for vascular access 
devices (VAD's). Also described are methods of disinfecting vascular access devices.
Patent AU-2022202925-A1 (AU)
Title: Thermosensitive hydrogel collagenase formulations
Inventor: YU BO
IPC: A61K47/34
Filed: 2022-05-02
Abstract: The present disclosure provides a formulation for injectable and topical collagenase, 
which will have extended residence time for the drug at the therapeutic targeted area for the 
indication being treated, a slow release formulation for collagenase, which is compatible with the 
active ingredient and does not adversely affect its activity, an injectable formulation for 
collagenase which can be effectively administered to a patient with a small size needle without 
exhibiting pre-gelation, which would interfere with the ability to deliver the required dose for 
treatment, and a water-based topical formulation for collagenase which will be more compatible 
with other topically used medications to achieve better results.
Patent AU-2022203171-A1 (AU)
Title: Brushing device with illumination features
Inventor: WAGNER ROBERT
IPC: A61C17/02
Filed: 2022-05-12
Abstract: The present disclosure relates to an oral cleansing device with illumination features. In 
one example, the device includes a housing including an aperture, such as a button 
aperture, defined therethrough, a diffuser connected to the housing and configured to span 
over the aperture. The device also includes a blocking member positioned over a portion of 
the diffuser and connected thereto and a lighting array received within the housing and at 
least partially aligned with the blocking member such that light emitted from the lighting array 
is transmitted to an exterior of the housing by traveling around the blocking member and 
through the diffuser.
Patent AU-2022206476-A1 (AU)
Title: Prime editor variants, constructs, and methods for enhancing prime editing efficiency and precision
Inventor: LIU DAVID
IPC: C12N15/11
Filed: 2022-01-11
Abstract: The present disclosure provides compositions and methods for prime editing with improved editing efficiency and/or reduced indel formation by inhibiting the DNA mismatch repair path way while conducting prime editing of a target site. Accordingly, the present disclosure provides a method for editing a nucleic acid molecule by prime editing that involves contacting a nucleic acid molecule with a prime editor, a pegRNA, and an inhibitor of the DNA mismatch repair pathway, thereby installing one or more modifications to the nucleic acid molecule at a target site with increased editing efficiency and/or lower indel formation. The present disclosure further provides polynucleotides for editing a DNA target site by prime editing comprising a nucleic acid sequence encoding a napDNAbp, a polymerase, and an inhibitor of the DNA mismatch repair pathway, wherein the napDNAbp and polymerase is capable in the presence of a pegRNA of installing one or more modifications in the DNA target site with increased editing efficiency and/or lower indel formation. The disclosure further provides, vectors, cells, and kits comprising the compositions and polynucleotides of the disclosure. The present disclosure also provides compositions and methods for prime editing with improved editing efficiency and/or reduced indel formation with modified prime editor fusion proteins. The disclosure further provides, vectors, cells, and kits comprising the compositions and polynucleotides of the disclosure.
Patent AU-2022220893-A1 (AU)
Title: A rope exercise simulation device
Inventor: RINGSHALL ADAM
IPC: A63B5/20
Filed: 2022-02-08
Abstract: A rope exercise simulation device comprising: a handle and an elongate housing with at least one internally located displaceable weight; wherein the housing extends substantially orthogonally with respect to an axis of the handle and the at least one weight is arranged to move between the ends of the housing acting against one or more resiliently deformable means.
Patent AU-2022221426-A1 (AU)
Title: System and Method for Composing Personalized Scratch-Off Lottery Tickets
Inventor: MARTINECK SR JEFFREY D
IPC: A63F3/06
Filed: 2022-08-23
Abstract: An instant lottery ticket game system and method includes a set of 
scratch-off lottery ticket blanks, each lottery ticket blank having a composition 
area and a separate game play area with play indicia that presents a pre
determined game outcome, the play indicia covered by a scratch-off coating 
(SOC). The set of lottery ticket blanks are housed within an automated 
dispenser. An interface is configured with the dispenser and is in communication 
with the printer, the interface configured to accept player input of personalized 
indicia for printing in the composition area. A printer is operably configured with 
the dispenser and is in communication with the interface via a controller. The 
printer prints the personalized indicia from the player in the composition area to 
generate a finished scratch-off lottery ticket prior to dispensing of the finished 
lottery ticket from the dispenser.
Patent AU-2022222471-A1 (AU)
Title: Immunoconjugates for targeted radioisotope therapy
Inventor: JUDGE ADAM
IPC: C07K16/28
Filed: 2022-02-18
Abstract: Described herein are immunoconjugates comprising an: a) antigen binding region; b) an immunoglobulin heavy chain constant region; and c) a radioisotope chelating agent; wherein the molecular weight of said immunoconjugate is between 60 and 110 kDa. The immunoconjugates can be used to deliver alpha and beta emitters for the treatment of tumors or cancer.
Patent AU-2022245339-A1 (AU)
Title: Populations of enriched regulatory t cells and methods for producing same
Inventor: PARMAR SIMRIT
IPC: C12N5/0783
Filed: 2022-03-25
Abstract: Provided herein are populations of enriched
Patent AU-2022246929-A1 (AU)
Title: Automated lawn application control system and methods therefor
Inventor: MCCLURE JR JAMES G
IPC: A01B69/04
Filed: 2022-04-07
Abstract: A system and method for automated lawn chemical treatment application are described. The system comprises a station having a series of concentrated chemicals capable of being mixed and diluted in a reservoir having a water supply to form a specialty formula and a craft which receives the specialty formula for dispersal. Various features of the craft enable a systematic treatment of various plants and/or areas of a law to reduce or eliminate the growth of unwanted plants while promoting the growth of desired plants. These may include the addition of imaging sensors and artificial intelligence to recognize unwanted plants versus desirable plants and develop means to inhibit or grow each over a specified period. A homeowner's ability to consistently treat plants with low-volumes of chemical treatments is enhanced, thus limiting environmental effects and reducing chemical waste.
Patent AU-2022270091-A1 (AU)
Title: Systems and methods for capturing carbon dioxide and regenerating a capture solution
Inventor: OSTERICHER ANDREW LOGAN
IPC: B01D53/62
Filed: 2022-05-03
Abstract: Techniques according to the present disclosure include capturing carbon dioxide from a dilute gas source with a CO
Patent AU-2022271449-A1 (AU)
Title: Dynamic tank management based on previous environment and machine measurements
Inventor: ANDERSON KENT MICHAEL
IPC: A01C21/00
Filed: 2022-11-17
Abstract: Historical information is accessed that describes a previous state of a field, previous 
environmental conditions for the field, and previous farming machine actions performed in the 
field. A tank management model is applied to the historical information to determine expected 
weed densities within field portions and an amount of treatment fluid required to treat plants 
within the field. While the farming machine is treating plants in the field, current information 
describing a current state of the field is accessed. The tank management model is applied to the 
current information to determine updated weed densities within field portions not yet treated.  
The farming machine performs a modified plant treatment action based on the updated weed 
densities and a comparison of a remaining amount of treatment fluid within a tank of the farming 
machine and an updated amount of treatment fluid for treating plants within field portions not yet 
treated.  
28713/49119/FW/15468878.1
8/9 
400 Access historical information 410 
Apply a tank management model to the accessed 
historical information to 420: 
Determine expected weed densities for 
field portions430 
Determine an amount of treatment 
fluid required to treat plants based on 
the expected weed densities 440 
Access current information describing a current state 
of the field 450 
Apply the tank management model to the accessed 
current information to determine updated weed 
densities 460 
Perform modified plant treatment action 470 
FIG. 4
Patent AU-2022315158-A1 (AU)
Title: Device, system and method for remote firefighting
Inventor: DICRISTOFARO VINCENZO
IPC: A62C31/00
Filed: 2022-07-18
Abstract: Firefighting devices and associated methods and systems for firefighting are described where the firefighting devices generally have a housing; at least one tank disposed in the housing and containing source material for a firefighting agent; a propellant system that is contained within the housing and operatively coupled to the at least one tank for deployment of the firefighting agent; a nozzle that is coupled to the propellant system for receiving and dispensing the firefighting agent; and a control unit that is coupled to the propellant system configured to autonomously control the firefighting device by activating the propellant system to discharge the firefighting agent through the nozzle to a portion of an operational region of the firefighting device based on analysis of sensor data obtained for a portion of the operational region or an adjacent area outside of the operational region or receipt of a signal from another device.
Patent AU-2022322810-A1 (AU)
Title: Class of cddo/tetramethylpyrazine alcohol heterocomplexes having combination therapy effect, and preparation method therefor and use thereof
Inventor: LING YONG
IPC: C07J63/00
Filed: 2022-07-27
Abstract: The present invention relates to the technical field of biomedicine, particularly to a class of CDDO/tetramethylpyrazine alcohol heterocomplexes having a combination therapy effect, and a preparation method therefor and the use thereof, wherein the CDDO/tetramethylpyrazine alcohol heterocomplex has a structure as represented by general formula I. According to the present invention, a dual-prodrug strategy is used, specifically, CUK of a CDDO drug is subjected to prodrug protection with a leucine acyl group of an LAP response fragment, and is coupled to an active fragment of tetramethylpyrazine alcohol to form a CDDO/tetramethylpyrazine alcohol heterocomplex. According to the present invention, in a liver inflammatory tissue with LAP overexpression, by means of selectively cleaving an amide bond fragment of leucine, the prodrug releases the CDDO drug and tetramethylpyrazine alcohol, so that the concentrations of the two drugs in the liver injury inflammatory tissue are increased, the therapeutic effect on inflammation is increased, the drug dosage is reduced, the toxicity and side effects of the CDDO drug are reduced, and the drug safety is improved.
Patent WO-2023137518-A1 (WO)
Inventor: ALDRICH-WRIGHT JANICE
IPC: A61K31/282
Filed: 2023-01-20
Abstract: La présente divulgation se rapporte à des complexes de platine, et en particulier à des complexes de platine (II) et de platine (IV). La présente divulgation se rapporte également à la synthèse des complexes de platine, et à des intermédiaires destinés à la synthèse des complexes de platine. La présente divulgation se rapporte également à des méthodes et à l'utilisation des complexes de platine destinées au traitement du cancer.