baber/WOPTO huggingface dataset:
Patent EP-0464101-A1 (EP)
Title: Improvements relating to the radio-labelling of proteins.
Inventor: FOXWELL BRIAN MAURICE JOHN
IPC: C07K19/00
Filed: 1990-03-23
Abstract: Nucleoside thiotriphosphates carrying <32>P in the gamma-thiophosphate group, prepared by reaction between a nucleoside diphosphate and a <32>P labelled thiophosphate salt, are used as thiophosphorylating agents for antibodies that bind to tumour-associated antigens. The labelled thiotriphosphates can be used to introduce a therapeutically useful <32>P atom into an antibody that has been modified by the incorporation into its structure of a peptide region capable of acting as a substrate for a phosphokinase. The resulting labelled antibody can then be used for injection in anti-tumour therapy and has clinical advantages over the corresponding phosphorylated analogue.
Patent EP-0428647-A1 (EP)
Inventor: MUELLER WALTER
IPC: F28C1/14
Filed: 1990-05-29
Abstract: L'installation réfrigérante est un réfrigérateur à sec, dit hybride, et présente des échangeurs de chaleur (1-4) dans lesquels le milieu à refroidir circule dans un circuit primaire fermé (P), sans venir en contact avec le milieu réfrigérant, l'air et l'eau. L'installation réfrigérante peut fonctionner soit à sec, soit en milieu partiellement ou totalement mouillé. Un dispositif de mouillage (12-15) raccordable individuellement et fonctionnant avec un excès d'eau est associé à chaque échangeur de chaleur rectangulaire, l'échangeur de chaleur étant constitué par des lamelles (32) disposées verticalement, dans lesquelles des tubes (28, 30) sont fixés perpendiculairement à celles-ci. Les échangeurs de chaleur sont montés inclinés par paires et forment un angle de 40°. L'installation renferme en outre un ventilateur (23) qui, suivant la température de l'air et le type de mouillage, est mis en marche à pleine vitesse de rotation ou à une fraction de celle-ci. Une telle installation réfrigérante permet une construction compacte et peut fonctionner avec un rendement élevé, tout en économisant de l'énergie.
Patent EP-0424545-A1 (EP)
Inventor: MURAYAMA HIROSHI KIRIN BEER KA
IPC: C12C11/00
Filed: 1990-05-15
Abstract: A method of producing sake, involving the step of heating fermented liquor, which comprises adjusting the dissolved oxygen concentration of prefermented liquor to less than 1 mg/l and heating the liquor at a given temperature within the range of 40 to 120°C for a time predetermined according to the required target value of the quantity of residual diacetyl precursor. This procedure serves to not only convert most of the diacetyl precursor contained in the prefermented liquor into diacetyl which can easily be decomposed by yeast, but also reduce the quantity of the diacetyl itself. As a result, it now becomes possible to dispense with a prolonged, low-temperature post-fermentation which has hitherto been necessary for reducing the diacetyl content and to greatly shorten the time necessary for producing sake.
Patent EP-0477213-A1 (EP)
Title: Methode d'analyse
Inventor: GARLAND PETER BRYAN HOPE COTTA
IPC: G01N21/55
Filed: 1990-06-11
Abstract: L'invention concerne des méthodes pour effectuer des analyses d'enzymes en utilisant une technique de spectrométrie de résonance de plasmon de surface (SPRS). Une surface SPRS porte un réactif immobilisé pouvant être libéré par un enzyme. On met un échantillon de liquide contenant ledit enzyme en contact avec la surface solide, la libération dudit réactif étant contrôlée par la SPRS.
Patent EP-0477277-A1 (EP)
Inventor: HEINSOHN HENRY G
IPC: C12N9/00
Filed: 1990-06-13
Abstract: L'invention concerne un procédé pour récupérer et purifier de la chymosine lors d'une fermentation pour la production microbienne de chymosine. Le mélange de fermentation est filtré de manière à réaliser un filtrat contenant ladite chymosine. On prépare d'abord ledit filtrat en l'ajustant à un pH faible, environ 2, et/ou en ajustant la concentration de sel dans ledit filtrat à au moins environ 2M. Le mélange aqueux du filtrat est mis en contact avec une résine phényle-sépharose, qui lie sélectivement ladite chymosine provenant du filtrat. Le filtrat qui reste après le contact avec ladite résine phényle-sépharose est rejeté, la colonne de résine phényle-sépharose étant éluée avec de l'eau ou avec une solution de sel dilué de manière à obtenir de la chymosine essentiellement pure lors d'une seule étape d'élution.
Patent EP-0443039-A1 (EP)
Inventor: KUBOTA MASAO
IPC: B66B23/12
Filed: 1990-09-07
Abstract: La machine transporteuse décrite comprend une partie de transport en marche avant et une partie de transport en marche arrière reliée à elle, est de construction simplifiée, présente un volume compact et un poids léger et s'adapte à une large gamme d'applications. Un escalier roulant à mouvement alternatif, utilisé comme dispositif transporteur, comprend plusieurs bases de marches (1, 2) disposées à proximité étroite sur des rails de guidage annulaires (01, 02) le long d'un parcours de transport comportant une section de marche avant (A - C) et une section de marche arrière (E - G) qui sont reliées entre elles par des sections de virage (D, H). Les bases adjacentes sont reliées basculantes par leurs extrémités à des points d'ossature à broches (011, 021, 012, 022) placés sur des colonnes (15, 25) des bases des marches et reliés entre eux par un mécanisme articulé à parallélogramme comportant des noeuds d'articulation (11, 12) flexibles autour de broches (110, 120) placées entre eux. Les bases des marches avancent sans à-coups le long du parcours du transport qui se compose d'une section montante (B), d'une section descendante (F) et d'une section incurvée. Une telle machine transporteuse, qui peut effectuer un mouvement alternatif pendant les opérations de transport, se caractérise par un degré de liberté élevé en ce qui concerne la disposition du parcours de transport, par une structure simplifiée, par un volume compact et par un poids léger et n'est guère sujette à des limitations d'installation et de construction, de sorte qu'elle est utilisable dans divers champs d'application.
Patent EP-0453570-A1 (EP)
Inventor: FUJITA NAOKI FANUC MANSION HAR
IPC: G05B19/4093
Filed: 1990-10-24
Abstract: Procédé de préparation d'un programme d'unité de commande numérique interactive pour un tour à deux broches, deux tourelles revolver et quatre axes en fonction des formes d'une pièce à usiner ainsi produite, subissant un usinage principal et un usinage secondaire. Le point entre les processus d'usinage principal et secondaire est déterminé (S1, S2, S3) en fonction des données relatives aux éléments constitutifs de la forme de la pièce à usiner introduits. Ce point dans le programme de commande numérique est sélectionné (S4 - S10) de sorte que le temps nécessaire pour l'usinage principal et l'usinage secondaire soit sensiblement égal. On peut ainsi préparer un programme très efficient pour la commande numérique d'un tour à quatre axes.
Patent EP-0454946-A1 (EP)
Inventor: GRUBER PETER
IPC: G01R19/25
Filed: 1991-01-24
Abstract: Instantaneous values y[k] of the measurement signal y[t] are generated by means of a sampling circuit (1), converted to digital values by means of an analog/digital converter (1a) and stored in a memory circuit (2) so that they are available at discrete times (k). In an estimator (3), estimated values (a0,e[k], an,e[k], bn,e[k], where n = 1,2,...,L) of the instantaneous values of Fourier coefficients of at least two required sinusoidal signals which have different frequencies known in advance are then determined from these and stored. From the stored estimated values, difference signals between measured instantaneous values (y[k]) and reconstructed instantaneous values of the measurement signal (y[t]) are generated successively in time which are then used for correcting the stored estimated values step by step. The corrected estimated values can then also be filtered in a low-pass filter (4) and the filtered estimated values (a0,e,m[kTs], an,e,m[kTs], bn,e,m[kTs]) can then be converted in a transformation circuit (5) by means of a nonlinear transformation into estimated values (A0,e[kTs], An,e[kTs],  PHI n,e[kTs]) of instantaneous values of the amplitudes and/or phases of required sinusoidal signals. The low-pass filter (4) and the transformation circuit (5) can be operated with a slower clock signal CL,s which has a clock period Ts which is a multiple of the period of the clock signal CL of the remaining arrangement. 
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Patent EP-0443489-A1 (EP)
Inventor: HASEGAWA YASUSHI C O R D LABOR
IPC: B22D27/04
Filed: 1991-02-18
Abstract: A high-nitrogen ferritic heat-resisting steel comprises, in weight per cent, 0.01 - 0.30% C, 0.02 - 0.80% Si, 0.20 - 1.00% Mn, 8.00 - 13.00% Cr, 0.50 - 3.00% W, 0.005 - 1.00% Mo, 0.05 - 0.50% V, 0.02 - 0.12% Nb and 0.10 - 0.50% N and is controlled to include not more than 0.050% P, not more than 0.010% S and not more than 0.020% 0, the balance being Fe and unavoidable impurities. The steel may optionally comprise (A) one or both of 0.01 - 1.00% Ta and 0.01 - 1.00% Hf and/or (B) one or both of 0.0005 - 0.10% Zr and 0.01 - 0.10% Ti. A method of producing the steel comprises melting and equilibrating the steel components in an atmosphere of a mixed gas of a prescribed nitrogen partial pressure or nitrogen gas and thereafter casting or solidifying the melt in an atmosphere controlled to have a nitrogen partial pressure of not less than 1.0 ata and a total pressure of not less than 4.0 ata, with the relationship between the partial pressure p and the total pressure P t  being
Patent EP-0447857-A1 (EP)
Inventor: SAWANISHI HIROYUKI
IPC: C07D223/20
Filed: 1991-03-01
Abstract: Novel polycyclic compounds represented by the following formula: A - (CH₂) n  - COOR¹, wherein R¹ represents a hydrogen atom or a lower alkyl group; n represents an integer of from 0 to 5; and A is a group represented by the following formula:
       
 wherein X represents a hydrogen atom or a halogen atom; and Y represents a methylene group, an oxygen atom, or a sulfur atom, or A is a group represented by the following formula:
       
 and pharmacologically acceptable salts thereof are disclosed. Also disclosed are a method for preparing the same, a pharmaceutical composition comprising the same, an antiallergic agent and an agent for bronchial asthma comprising the same, and a method for treatment of an allergic disease or bronchial asthma comprising the step of administering the same.
Patent EP-0447963-A1 (EP)
Inventor: STABEL UWE DR
IPC: C07C29/17
Filed: 1991-03-14
Abstract: Process for the preparation of 1,4-butanediol by catalytic hydrogenation of maleic anhydride in the presence of alcohols at elevated temperature and at elevated pressure and with the aid of a cobalt-containing catalyst by partial hydrogenation of the reaction mixture in a first hydrogenation step at temperatures of 100 to 200 DEG C and a pressure of 30 to 200 bar and subsequent full hydrogenation of the hydrogenation product obtained from this first step without further workup at higher temperatures and at a higher pressure than in the first hydrogenation step in a second hydrogenation step at temperatures of 200 to 300 DEG C and a pressure of 200 to 350 bar.
Patent EP-0478884-A1 (EP)
Inventor: MAUSNER EBERHARD
IPC: F02D11/10
Filed: 1991-04-12
Abstract: The invention proposes a load adjusting apparatus with a control element (8) for acting on at least two actuators (9a, 9b) determining the output of an internal combustion engine. The control element is spring-connected to a driver (3) which can be actuated via an accelerator pedal (1) and in addition can be moved by means of an electrical servo drive (10). A reference value detection element (5) is assigned to the driver and an actual value detection element (22) acting in concert with this element (5) and acting on the electrical servo drive is provided, the electrical servo drive being actuatable as a function of the detected values of an electronic control device (6). The actuators are in particular designed as throttle valves, it being possible to form an operating connection between the driver and all actuators and between the electrical servo drive and at least one of the actuators. 
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Patent EP-0512132-A1 (EP)
Inventor: STEINKE ALEXANDER
IPC: G21C3/32
Filed: 1991-05-03
Abstract: The fuel element consists in the normal way of a head-piece, fuel rods and guide tubes with spacers and a bottom nozzle, but the design of the bottom nozzle is simplified. The fuel rods stand on a thin perforated sheet (33, 34) having many small openings for retaining foreign bodies, while the guide tubes (25, 26) penetrate the perforated sheet and are screwed in a baseplate (21) which is attached via an apron (32) to the perforated sheet and carries both relatively large inlet openings for the cooling medium and centring bores at the corners. A tube length (20) is attached to the underside of the baseplate. <IMAGE>
Patent EP-0467070-A1 (EP)
Inventor: PALM ERICH
IPC: F16B31/02
Filed: 1991-06-12
Abstract: It is intended to mount sealing webs (2) directly into a support (10) with a low pull-out resistance, for example into aerated concrete, using a screw consisting of a shank (1) and a screw head (4). A washer (3) is inserted under the screw head (4). Constructed on the circumferential region of the screw head (4) is a profiling in the form of a milled edge (6), which considerably increases the insertion torque of the screw and, in the directly final screwing-in section, digs into the countersink opening of the washer (3), which cannot rotate as a result of friction and/or force-locking, and thus considerably increases the torque. As a result of this increase in torque as the screw is screwed in, the torque coupling of a screwdriver is initiated, thus preventing overrotation of the shank (1) which is provided with a coarse thread pitch. <IMAGE>
Patent EP-0482332-A1 (EP)
Inventor: SCHMIDT HANS
IPC: B01F3/04
Filed: 1991-09-10
Abstract: For the purpose of aerating waste waters, a tubular main body (1) is surrounded with an elastic perforated membrane (4), via the perforations of which, when pressurised, the compressed air is distributed in fine bubbles into the liquid via openings in the main body and, when unpressurised, tightly encloses the main body. A connecting element is provided which connects the main body to a compressed-air feed tube (3) and supports it. The main body itself is manufactured from a commercially available piece of tube and is provided with a fixing element and at least one radial air passage opening (6), the connecting element provided between the main body and the compressed-air feed tube being a supporting body (2), one end of which passes through the compressed-air feed tube and the other end of which, that end which lies opposite the air feed tube, engages in the main body, providing support and sealing against the liquid. The connecting element (2) has at least one axially extending air feed line (7), which guides the compressed air to the radial air outlet opening of the main body. 
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Patent EP-0540763-A1 (EP)
Inventor: NAKANUMA TADASHI
IPC: H03M3/02
Filed: 1991-10-09
Abstract: Method and apparatus for producing pulses in accordance with the change of a physical quantity, wherein each time an electric pulse is produced, the value of the physical quantity is sampled and held; and each time the physical quantity has changed by a prdetermined reference amount with respect to the sampled and held value thereof, one output electric pulse is produced to cause the sampled and held value to be replaced by the value of the physical quantity at that time; and the above operations are repeated to produce a series of output pulses whose number corresponds to the amount of change of the physical quantity. By counting the number of the output pulses it is possible to know the amount of change, and by changing the reference amount it is possible to change the interval or density of the output pulses thereby to change the resolution.
Patent EP-0489299-A1 (EP)
Inventor: SIEGEL BERND DR
IPC: C07C317/36
Filed: 1991-11-19
Abstract: Sulphonyl compounds of the formula <IMAGE>  in free form or in the form of their salts, in which     Ar denotes the radical of a benzene or naphthalene ring, R<1> and R<2> each denote hydrogen, optionally substituted C1-C4-alkyl, optionally substituted phenyl, C1-C4-alkoxy, carboxyl, C1-C4-alkoxycarbonyl, cyano, halogen or hydroxysulphonyl,   R<3> denotes nitro, amino, C1-C4-alkanoylamino or benzoylamino and   R<4> denotes a radical of the formula <IMAGE> or <IMAGE> in which   X<1>, X<2> and X<3> each represent hydrogen, optionally substituted C1-C4-alkyl, or optionally substituted phenyl and X<4> represents a group which can be removed under alkaline reaction conditions,   their preparation and their use for the synthesis of reactive dyes.r
Patent EP-0447267-A1 (EP)
Inventor: UEDA KENJI
IPC: B01J23/68
Filed: 1991-03-15
Abstract: The invention presents catalysts for producing phthalic anhydride by vapor phase catalytic oxidation of orthoxylene and/or naphthalene with molecular oxygen or gas containing molecular oxygen. The catalyst is prepared by supporting a catalytic active substance comprising 1 to 20 parts by weight (hereinafter abbreviated "parts") of vanadium oxide as V₂O₃, 99 to 80 parts of anatase type titanium dioxide with specific surface area of 10 to 60 m²/g as TiO₂ and per 100 parts of the sum of these two ingredients, 0.05 to 1.2 parts of at least one element selected from potassium, cesium, rubidium and thallium as oxide, and 0.05 to 2 parts of silver as Ag₂O on a heat resistant inorganic carrier. The catalyst may also contain, per 100 parts in total of vanadium oxide and titanium dioxide, 0 to 1 part of niobium as Nb₂O₅, 0 to 1.2 parts of phosphorus as P₂O₃, and 0 to 5 parts of antimony as Sb₂O₃ (however, contents of niobium, phosphorus and antimony will not be zero at the same time).
Patent EP-0454436-A1 (EP)
Inventor: CHAKRABARTI JIBAN KUMAR
IPC: C07D333/20
Filed: 1991-04-24
Abstract: 2-Methyl-10-(4-methyl-1-piperazinyl)-4H-thieno-[2,3-b][1,5]benzodiazepine, or an acid salt thereof, has pharmaceutical properties, and is of particular use in the treatment of disorders of the central nervous system.
Patent EP-0486127-A1 (EP)
Inventor: PERRIMAN VICTOR HERBERT
IPC: B42D5/00
Filed: 1991-05-28
Abstract: A record pad (1) comprising a plurality of sheet sets (2) each set comprising at least one removable top copy sheet (3) and an underlying record copy sheet (4) in which the top copy sheet (3) lies in close juxtaposition to the underlying record copy sheet (4) and bears a strip of repositionable adhesive adjacent an edge of the record copy sheet and in which one edge of record copy sheet (4) extends beyond the edge of the top copy sheet to provide a margin (5) which margin (5) serves to be secured to other margin (5) of the pad for record purposes.
Patent EP-0496172-A1 (EP)
Inventor: MATSUZAKI SHIN-ICHI
IPC: G01C19/38
Filed: 1991-12-31
Abstract: A bias correction apparatus comprising a gyro (43), bias calculation means for reading output data of the gyro (43) after every fixed period (To) after the apparatus is turned on and for calculating a bias value of the gyro (43) on the basis of the read output data, storage means for storing the bias value calculated by the bias calculation means, and bias correction means for correcting angular velocity data (δϑ) of a vehicle obtained from the gyro output data with the bias value stored in the storage means. When calculating a first bias value after the apparatus is turned on, the bias calculation means calculates the bias value by reading the gyro output data every period (T) shorter than the certain fixed period (To) (=>T<To).
Patent EP-0441706-A1 (EP)
Inventor: BEDEL PHILIPPE
IPC: G05D1/10
Filed: 1991-02-07
Abstract: The computer intended especially for the automatic piloting of the missile, comprises an internal bus (80), a central unit (10) coupled to the internal bus and comprising a central processor (11) with a clock circuit, memories (20) associated with the central processor, and input/output circuits (40, 50, 60, 70) coupled to the internal bus and permitting coupling of the computer to external links which are intended to link the latter to means of emission and of transmission of information transmitted by radio waves and to members of the missile, an algorithmic processing unit (30), distinct from the central unit (10) is provided to effect rapid calculations, and comprises at least one processor, memory circuits associated with the latter, and a double-access memory linking the algorithmic processing unit to the internal bus (80) of the computer, and the input/output circuits comprise at least one coupling circuit (40) having a processor, memory circuits associated with the latter, at least one interface circuit with an external link terminating at the computer, and a double-access memory linking the coupling circuit to the internal bus (80) of the computer. <IMAGE>
Patent EP-0468843-A1 (EP)
Inventor: GUICHON JEAN-PAUL
IPC: A47C5/12
Filed: 1991-07-10
Abstract: The device for articulating an arm-rest of an armchair made of plastic material to the back, permitting the automatic fitting by downward pushing of this arm-rest onto the rest of the armchair, comprises two pins (14) aligned in a substantially horizontal direction and projecting from the two sides of an integrally moulded bracket (13) protruding laterally on the outer edge corresponding to the back (2) made of plastic material, these pins being intended to penetrate, by means of elastic bending of downward wings (17, 18) of the arm-rest (3) made of plastic material, into holes (17, 19) of these wings in order to be held thereby and to pivot therein. <IMAGE>
Patent EP-0488887-A1 (EP)
Inventor: BEDIN JEAN
IPC: B65C9/06
Filed: 1991-11-27
Abstract: The subject of the invention is a positioning device for bottles, or similar containers, especially for processing machines such as labelling or packaging (sealing) machines, each bottle processed being equipped with an indent (stud) intended to engage with an associated element of the positioning device. 
<??>According to the invention, the positioning device (4 to 11) is arranged so that the said associated element (4) exerts on the bottle, when it is not engaged with its indent (stud) (1), a thrust which tilts it and brings at least one point of a generatrix of its lateral surface into frictional contact with at least one wall (12), during the relative displacement of the said bottle and of the said wall. 
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Patent EP-0446156-A1 (EP)
Inventor: JORDA RAFAEL
IPC: C08G18/61
Filed: 1991-03-05
Abstract: A hydrolytically degradable polyester-silicone jointly crosslinked copolymer which is the product of reaction: 
 
  a) - of at least one diorganopolysiloxane containing, per molecule, hydroxyl functional groups, each bonded to silicon atoms via a Si-C bond, 
  b) - a polylactic and/or polyglycolic  alpha , omega -diol polyester oligomer, 
  c) - an organic polyisocyanate. 
 
<??>The jointly crosslinked copolymers according to the invention can be employed in particular as a matrix containing an active principle with a view to the controlled release of the active principle by simple erosion of this matrix by hydrolysis.
Patent EP-0514405-A1 (EP)
Title: Strain ral-4, useful for production of small proteins and peptides.
Inventor: LEPLEY ROBERT ALAN
IPC: A61K38/00
Filed: 1991-01-18
Abstract: This invention presents a novel strain of E. coli, RAL-4, which is a tryptophan auxotroph and shows enhanced expression of proteins and peptides. In addition, this invention presents a method for achieving enhanced expression of proteins and peptides either by the use of RAL-4 or via generation of a host cell auxotrophy for an amino acid not resident in the heterologous protein to be expressed. In an embodiment of the invention, IGF-I and GRF are exprressed at levels above that found in wild type controls