baber/WOPTO huggingface dataset:
Patent EP-0961280-B1 (EP)
Inventor: HEILIGERS JOANNES HERMANUS
IPC: B65D85/86
Filed: 1996-11-20
Granted: 2002-01-30
Abstract: This invention relates to the use of a linear dialkyl peroxide having an hexyne or an hexene backbone, for producing a controlled rheology polypropylene heterophasic copolymer of melt index Ml2 larger than 15 g/10 min, having simultaneously a very high impact resistance and a high flexural modulus. <IMAGE>
Patent EP-0979612-B1 (EP)
Inventor: HIRAMOTO TADAHIRO
IPC: A23K1/18
Filed: 1999-08-02
Granted: 2003-11-19
Abstract: A method for more fundamentally reducing or eliminating the odor of animal excreta (feces, urine, etc.) which can be relatively easily performed and is advantageous economically; a compounding ingredient to be used in this method; and feeds, pet foods or foods containing the above compounding ingredient are disclosed. The feeds, pet foods or foods contain a compounding ingredient which comprises one or more extracts selected from the group consisting of the extracts of rosemary, sunflower seeds, fresh coffee beans, grape pericarp, grape seeds, apple, carrot leaves and tea leaves and an enzyme capable of oxidizing phenolic compounds.
Patent EP-1000542-B1 (EP)
Inventor: CUPFERMAN SYLVIE
IPC: A61P31/04
Filed: 1999-10-18
Granted: 2002-06-12
Abstract: An antimicrobial system comprises at least one polyol (selected from 4-8C polyols, glycerol mono-(3-9C alkyl) ether or glycerol (3-9C alkenyl) ether) and 2-hydroxy-4-(1-methylethyl)-cyclohepta-2,4,6-triene-1-one. Independent claims are also included for: (1) an antimicrobial system comprises at least one polyol (selected from octane-1,2-diol, pentane-1,2-diol, sorbitol, glycerol mono-(3-9C alkyl) ether or glycerol (3-9C alkenyl) ether) and sodium capryl-lactyl-lactylate; and (2) a composition comprising at least one of the antimicrobial systems described above.
Patent EP-0972600-B1 (EP)
Inventor: BILAND MAX
IPC: B23D33/02
Filed: 1999-07-06
Granted: 2002-09-11
Abstract: The system includes a sheet metal guide (4) with at least one table (5), which guides the sheet panel (3), movable horizontally between an upper and a lower plate (6,7). Facilities (8) are provided for sound insulating and clamping the sheet panel (3), arranged between the two plates (6,7).
Patent EP-0950774-B1 (EP)
Inventor: HUMMER JOSEF
IPC: E04B7/22
Filed: 1999-02-19
Granted: 2004-07-14
Abstract: The roof element (1) has longitudinal metal sheet sections (2) filled within an insulator (3) and arranged next to each other. A number of metal sections are fixed together by end-supported carrier sections (4) to a precast lay unit. The carrier sections have a C-shaped cross-section with an opening (6) in the front for an insulator filling (9).
Patent EP-1062711-B1 (EP)
Inventor: MESECHER DAVID K
IPC: H04B1/38
Filed: 1999-01-07
Granted: 2007-06-13
Abstract: An improved base station which cancels the effects of known fixed interference sources and produces a signal substantially free from the interference sources thereby increasing total channel capacity. The adaptive interference canceller base station includes a main antenna for receiving signals from other communication stations and at least one directional antenna directed toward an interference source. The main and directional antennas are coupled together such that an output signal substantially free from the interference is generated.
Patent EP-1079693-B1 (EP)
Inventor: GRIMSLAND AAGE
IPC: A22B3/00
Filed: 1999-05-10
Granted: 2002-03-06
Abstract: A method and apparatus for producing and maintaining a gas mixture in one or more phases, in which the phases are generated in zones of, for example, a stunning tunnel or a stunning shaft. The gas mixture includes carbon dioxide gas and oxygen gas, and the concentration of air is maintained at a level equivalent to a concentration level in air. Carbon dioxide is added based on the measured level of carbon dioxide in each zone.
Patent EP-1082138-B1 (EP)
Inventor: SESSLER JONATHAN L
IPC: A61K41/00
Filed: 1999-06-04
Granted: 2004-08-25
Abstract: Texaphyrin/chemotherapeutic drug conjugates, optionally including a platinum(II) or platinum(IV) metal chelating site and/or complex, are useful for treating atheroma, tumors and other neoplastic tissue, neovascular-related diseases, as well as other conditions that are typically responsive to chemotherapy, radiation sensitization and photodynamic therapy.
Patent EP-1098878-B1 (EP)
Inventor: YUE CHRISTOPHE
IPC: C07D409/14
Filed: 1999-07-16
Granted: 2003-12-17
Abstract: Novel compounds which are inhibitors of the binding of fibrinogen to the Gp IIb/IIIa platelet receptors, and which can be used therepeutically as antithrombotic agents
Patent EP-1100553-B1 (EP)
Inventor: TETREAULT STEPHANE
IPC: A61F13/00
Filed: 1999-07-28
Granted: 2002-06-26
Abstract: A biocompatible monomer composition includes: (A) at least one monomer, which forms a medically acceptable polymer, (B) at least one plasticizing agent present in the composition in an amount of from 0.5 wt. % to 15 wt. % of the composition; and (C) at least one acidic stabilizing agent having a pKa ionization constant of from about 1 to about 7. The composition can be applied to a variety of materials and is particularly suitable as in vivo tissue adhesive. A method of joining together in vivo two surfaces, e.g., body tissues, includes (a) holding damaged tissue edges together to form abutted tissue surfaces; (b) applying to the abutted tissue surfaces an excessive amount of a composition containing 1) at least one monomer, which forms a medically acceptable biodegradable polymer, 2) at least one plasticizing agent; and 3) at least one acidic stabilizing agent; and (c) maintaining the surfaces in contact until the composition polymerizes to form a thick film of polymerized composition bridging the abutted tissue surfaces.
Patent EP-1112192-B1 (EP)
Inventor: SLADE BRIAN
IPC: A61L9/12
Filed: 1999-09-08
Granted: 2002-05-02
Abstract: Le distributeur de liquide volatile de l'invention est conçu pour équiper un véhicule. Il comprend un récipient à liquide conique fermé en grande partie (2). Deux plaques (14, 28) fermant la partie supérieure du contenant forment entre elles une interface capillaire (88) conduisant à un élément de diffusion poreux (42). Lorsque le véhicule est en mouvement, le liquide éjecté vers le haut ou vers l'extérieur, pendant les accélérations du véhicule, s'écoule vers les plaques puis dans les passages capillaires au niveau de l'interface pour atteindre l'élément poreux. Le contenant est soumis à une rotation par sa partie inférieure qui permet de l'orienter selon un angle correspondant à l'inclinaison de la surface du liquide, afin que tout le liquide puisse atteindre les plaques pour être distribué.
Patent EP-1105108-B1 (EP)
Inventor: GENNADIOS ARISTIPPOS
IPC: A61K47/36
Filed: 1999-08-24
Granted: 2007-01-03
Abstract: Gelatin-free capsule for use in oral administration of medicines, cosmetic or bath applications, or dietary supplements can be prepared from compositions comprisinga) 8-50% by weight of water-dispersible or water-soluble plasticizer,b) 0.5 to 12% by weight kappa-carrageenan,c) 0 to 60% dextrins, andd) 1% to 95% by weight water,with the kappa-carrageenan comprising at least 50% by weight of all gums forming or contributing to formation of thermoreversible gels in the composition. A capsule for oral administration or cosmetic application may comprise a fill material to be administered to a patient or subject and a capsule, the capsule comprising an aqueous based film comprisinga) water-dispersible or water-soluble plasticizer, andb) carrageenan,with the carrageenan comprising at least 50% or 75% by weight of kappa-carrageenan, and the carrageenan comprising at least 50% or 75% by weight of all gums which form or contribute to the formation of thermoreversible gels. A process for forming the capsules may comprise heating the composition, casting or extruding the composition into a film, gelling the composition by cooling, associating a fill material with the gelled composition (usually as a film) and sealing the film about the fill material.
Patent EP-1131931-B1 (EP)
Title: Procede et appareil de repartition de charge dans un reseau
Inventor: ADELMAN KENNETH ALLEN
IPC: G06F13/00
Filed: 1999-10-15
Granted: 2009-04-29
Abstract: La présente invention porte sur un système agglomératif de réseaux de protocole Internet qui permet d'obtenir un système extrêmement modulable optimisant le débit des messages par un équilibrage de charge adaptatif de ses composants, et réduisant le retard et la perte de paquets notamment en mode TCP par un processus auxiliaire contrôlé.
Patent EP-1130988-B1 (EP)
Inventor: ROSSI FABRICE
IPC: A47J27/05
Filed: 1999-11-19
Granted: 2003-05-28
Abstract: A cooking element for a steamer, composed of: a tubular side wall; a removable perforated bottom, the tubular side wall having an interior surface provided with a shoulder on which the perforated bottom rests; a first element carried by the interior surface of the tubular side wall; and a second element carried by, and located beneath, the perforated bottom. The first element is located to block the second element when the perforated bottom rests on the shoulder, one of the elements is a tongue, and the other of the elements is an abutment. A cooking element for a steamer, composed of a tubular side wall, a removable perforated bottom and a removable handle, wherein the perforated bottom has orifices adapted for rapid connection of the removable handle.
Patent EP-1133501-B1 (EP)
Inventor: DOZOL JEAN-FRANCOIS
IPC: C22B3/26
Filed: 1999-11-24
Granted: 2003-02-12
Abstract: The invention concerns novel calixarenes of formula (I) wherein: R1 is an alkyl or aryl group, or a hydrogen atom; R?2 and R3¿, identical or different, are alkyl or aryl groups; n is an integer ranging from 2 to 8; and p is an integer ranging from 4 to 8. Said calixarenes can be used for extracting actinides and lanthanides from aqueous solutions.
Patent EP-1131459-B1 (EP)
Inventor: BUISMAN CEES JAN NICO
IPC: C12R1/01
Filed: 1999-11-16
Granted: 2003-07-30
Abstract: A process was found for the conversion of elemental sulphur to hydrogen sulphide under ambient temperature and pressure. The biological hydrogen sulphide production process described is less expensive than both the chemical production of hydrogen sulphide and the biological hydrogen sulphide production from diluted sulphate containing waste water streams. Except for economical benefits also safety advantages exist compared to the chemical production of hydrogen sulphide, which is achieved at elevated temperature and pressure. The hydrogen sulphide produced can be used for the recovery of heavy metals.
Patent EP-1128777-B1 (EP)
Inventor: KUMAR AJAY
IPC: A61C8/00
Filed: 1999-11-12
Granted: 2007-10-31
Abstract: The invention relates to a coated tool bit for a dental drilling/cutting system. The tool bit is used to prepare an osteotomy in the jawbone of a patient. The tool bit is coated with a hard carbon coating/film. The coating can comprise diamond-like carbon (DLC), amorphous diamond, crystalline diamond, or a combination thereof. The tool bit includes drilling bits, threadformers, counterbores, and cutting tips of osteotomes. Some of the advantages of the coated tool bit are reduced friction, enhanced cutting efficiency, improved heat dissipation, increased resistance to wear and corrosion, and reduced adhesion to bone, tissue and other debris.
Patent IT-1305543-B1 (IT)
Inventor: BARATTINI BRUNO
IPC: G01F1/075
Filed: 1998-09-28
Granted: 2001-05-09
Abstract: An assembly (1) for determining water consumption along a water mains intake pipe (3), the assembly (1) having at least one remote detecting unit (4) having a meter (6) located along the intake pipe (3) and for generating an output signal (S) related to water consumption by a user connected to the intake pipe (3); the remote detecting unit (4) having an electronic processing device (7) which is supplied electrically and cooperates with the meter (6) to receive and process the output signal (S) and to memorize data relative to water consumption; the remote detecting unit (4) having a transmitting device (8) cooperating with the electronic processing device (7) and for transmitting the memorized data; and the assembly (1) also having at least one central processing unit (5), which is situated in a remote location with respect to the intake pipe (3), has a receiving device (10) for receiving the data transmitted by the remote detecting unit (4), and has a processing and monitoring unit (11) for processing and monitoring the data. <IMAGE>
Patent IT-1315212-B1 (IT)
Inventor: MORRONE RAFFAELE
IPC: C12P7/40
Filed: 1999-07-26
Granted: 2003-02-03
Abstract: A process for the resolution of enantiomeric mixtures of a chiral carboxylic acid, including an esterification reaction of the carboxylic acid in an organic solvent, in the presence of a stereoselective hydrolase, characterized in that an orthoester of the formula R<SUP>1</SUP>-C(OR<SUP>2</SUP>)<SUB>3</SUB>, in which R<SUP>1 </SUP>is selected from H and C<SUB>1</SUB>-C<SUB>4</SUB>alkyl and R<SUP>2 </SUP>is C<SUB>1</SUB>-C<SUB>8</SUB>alkyl or -CH<SUB>2</SUB>-C<SUB>6-10</SUB>aryl, is used as the esterification reactive.
Patent IT-1301808-B1 (IT)
Inventor: CRIPPA BRUNO
IPC: A42B3/22
Filed: 1998-06-25
Granted: 2000-07-07
Abstract: A crash-helmet with a device for locking and releasing movable parts comprising a helmet body (1) and a part (2) which is associated with the helmet body and is movable with respect to the helmet body along a movement path. The device for locking and releasing the movable part comprises a first member (3), which is associated with the movable part (2) and is provided with engagement regions which are mutually spaced along the movement path, and a second member (5), which is associated with the helmet body (1) and is provided with at least one retention element (9a, 9b) which engages at least one of the engagement regions. The retention element is flexible in order to allow the movement of the movable part (2) with respect to the helmet body (1), sequentially engaging the engagement regions when the movable part (2) moves with respect to the helmet body (1). The device also comprises a locking member (6) which can engage the retention element in order to prevent its elastic yielding, locking the movement of the movable part (2) with respect to the helmet body (1), or can be disengaged from the retention element to allow its elastic yielding. <IMAGE>
Patent IT-1275610-B1 (IT)
Title: Motorised column for rotating wings of gates or the like
Inventor: DONADI MORENO
IPC: E06B/
Filed: 1994-01-28
Granted: 1997-08-06
Abstract: The invention refers to a motorised column for rotating wings of gates or the like. The column comprises a bearing structure, with base to fix to the ground, inside which a rotating shaft is fixed with at least one radial arm to fix to the wing of a gate or similar. The rotating shaft is associated with rotation drive components integral with the bearing structure. <IMAGE>
Patent IT-1265522-B1 (IT)
Inventor: BARILLI LUIGI
IPC: A22C11/00
Filed: 1993-02-26
Granted: 1996-11-22
Abstract: The invention relates to the field of processes for preparation of foodstuffs in sacks, in particular mortadella, and precisely it relates to a process for forming food in sacks which provides, subsequently to an extrusion of a principal mixture, fo an extrusion of a second mixture internal to the principal mixture and designed to give identification to single slices of the product with a well-defined design formed by extrusion of the second mixture.
Patent IT-1265584-B1 (IT)
Title: Macchina per la pesatura, la dissoluzione e il trasferimento  automatico di coloranti in polvere o simili e dispositivo relativo.
Inventor: SCATIZZI MARIO
IPC: B05C/
Filed: 1993-01-29
Granted: 1996-11-22
Abstract: Il nostro trovato consente di utilizzare più silos di stoccaggio e unità eroganti, disposti in semplice o duplice fila su di una struttura di forma circolare. La particolare forma circolare permette di utilizzare, all'occorrenza, due unità di lavoro o pesatura poste su carrelli mobili e quindi di poter pesare contemporaneamente due formulazioni diverse raddoppiando così il lavoro globale della macchina. Inoltre con l'utilizzazione combinata della nostra apparecchiatura di dissoluzione e di trasferimento automatico dei coloranti pesati alle rispettive macchine di tintura, si completa il cielo automatico di gestione e manipolazione del colore eliminando qualsiasi contatto manuale o altro degli operatori con le materie coloranti.
Patent IT-1276352-B1 (IT)
Title: Gripper, particularly for demolishing concrete artefacts
Inventor: PACELLI MARCELLO
IPC: E04G/
Filed: 1994-11-11
Granted: 1997-10-30
Abstract: The invention relates to a gripper 1, particularly for demolishing artefacts, comprising two claws 2 hinged approximately centrally 3 and connected at the non- demolishing end to means of actuation 4, each having at least two crushing teeth 8, 9, one inside and one outside, and chopping means 6, and a cover element 5 that covers the said means of actuation 4 and all associated components, which partially enclose the said claws 2 as well. <IMAGE>
Patent IT-1266004-B1 (IT)
Title: Grab type feeder for strips of sheet metal
Inventor: DALLAN SERGIO
IPC: B21D/
Filed: 1993-07-29
Granted: 1996-12-16
Abstract: Grab type feeder for strips of sheet metal, characterised in comprising at least one continuous flexible conveyor 16, 16', 16", having at least one rectilinear segment running parallel to one edge of the strip of sheet metal 12 being advanced and having a plurality of grabs 20 applied to it, and means 18, 18' of activating the closing of said grabs 20 at said rectilinear segment to clamp the lengthwise edge of said strip of sheet metal placed between them. <IMAGE>
Patent IT-1267750-B1 (IT)
Title: Home and professional steam generator
Inventor: FALCI RENZO
IPC: F22B/
Filed: 1994-06-06
Granted: 1997-02-07
Abstract: The steam generator in accordance with this invention is particularly suitable for cleaning the windows and passenger compartments of motor vehicles. It is composed essentially of a tank, not under pressure, containing the water to be vaporised, a delivery pump, a check valve and an original vaporiser fitted with an elastic diaphragm suitable for maintaining a constant flow of steam to the user device, at a constant and pre-established pressure. These operations are carried out automatically. <IMAGE>
Patent JP-2881422-B1 (JP)
Title: コンクリートの圧縮試験装置用鋼製キャップ
IPC: G01N3/08
Filed: 1998-04-09
Granted: 1999-04-12
Abstract: 【要約】
【課題】  鋼製キャップとゴムパッドとの間のエアー溜 まりを容易に排出することができ、作業時間の短縮が図 られて圧縮試験の作業能率が向上するコンクリートの圧 縮試験装置を提供する。
【解決手段】  コンクリートの圧縮試験装置用鋼製キャ ップであって、前記鋼製キャップ２Ａ，２Ｂは、第１部 材３と第２部材４とを係合してなるもので、第１部材３ は筒状で、前記コンクリート製供試体１の外径よりやふ 大きい内径の嵌合穴３ａを有する環状体であって、該環 状体の軸方向下端側に段部を介して前記嵌合穴３ａより も大径の被係合部３ｂが形成され、この被係合部３ｂと 前記嵌合穴３ａとの間の段部３ｃを含み、かつ、嵌合穴 ３ａ側から外周面３ｄに貫通する小孔５を穿設してお り、第２部材４は略円盤体であって、上面に形成した円 形凸部４ａの外周に前記第１部材３の被係合部３ｂに係 合する係合部４ｂが形成され、かつ、円形凸部４ａの端 面４ｃを前記コンクリート製供試体１に対する加圧面と されてなり、この加圧面上にゴムパッド８を配設してな る。
Patent JP-2976205-B1 (JP)
Title: 移載装置の自動ストッパー機構
IPC: B65G47/52
Filed: 1998-07-27
Granted: 1999-11-10
Abstract: 【要約】
【課題】  コンベヤラインの端部に対する無人運搬車の 到着、発車の動きを利用して作動状態と解除状態とが切 り換わる自動ストッパー機構を提供する。
【解決手段】  支持ピンを回転軸としてぶら下がる無人 運搬車側のストッパー部材が、前記支持ピンよりも上方 のストッパー部が無人運搬車のコンベヤの上面よりも上 方に突出する形態で揺動自在に取り付けられ、他方、支 持ピンを回転軸としてぶら下がるコンベヤライン側のス トッパー部材が、支持ピンよりも上方のストッパー部が コンベヤラインの上面よりも上方に突出する形態で揺動 自在に取り付けられている。前記二つのストッパー部材 の支持ピンより下方の部分に、相互に干渉する要素が設 けられ、二つのストッパー部材は、無人運搬車の到着、 発車の動きに合わせて作動状態と解除状態とに切り換わ る。
Patent JP-2986782-B1 (JP)
Title: 多真円リールドラム
IPC: B21C47/30
Filed: 1998-09-02
Granted: 1999-12-06
Abstract: 【要約】
【課題】  外径を拡縮可能な多真円リールドラムを提供 する。
【解決手段】  ドラム軸８と、周方向で３箇所以上に分 割し、各々の周方向分割接合部が径方向に弾性変形可能 で、内径側に勾配部１ａをそれぞれ設けたセグメント １，２と、ドラム軸の軸心内を軸方向に移動するように 貫通させた中空ロッド７及び中心ロッド６と、中空ロッ ド及び中心ロッドを軸方向に移動させる手段と、各セグ メント１の勾配部と係合する勾配部３ａを外周側にそれ ぞれ設け、ドラム軸にそれぞれ軸方向に移動自在に内径 側を係合させて中空ロッド又は中心ロッドと連結したス プレッダ３と、各セグメント１，２の周方向分割接合部 の内側において、内径側に勾配部をそれぞれ設けたサブ セグメント４と、各サブセグメントの勾配部と係合する 勾配部を外周側に設け、軸方向に移動するように内径側 をドラム軸に係合させて中心ロッド又は中空ロッドと連 結したサブスプレッダ５とを具備する。
Patent NO-328093-B1 (NO)
Inventor: KAPLAN ANDREAS
IPC: C07C231/02
Filed: 2001-10-24
Abstract: New  beta -Hydroxyalkylamides.  beta -Hydroxyalkylamides of formula (I) are new. R1 = H or 1-10C alkyl; and R2 = 1-5C alkyl. An Independent claim is also included for the preparation of (I).
Patent NO-319653-B1 (NO)
Inventor: BEHR KRISTIAN
IPC: F25D23/00
Filed: 2003-09-23
Abstract: The present invention concerns a cover for a refrigerated merchandising storage unit (1) for display and sale of foodstuffs and the like comprising a storage compartment (8) having an essentially rectangular top opening (7) with the cover including two displaceable lids (10a, 10b) arranged in two rows the long sides (2, 4) of the storage unit (1) so that good access is provided to the storage compartment (8), wherein the cover is provided with a stationary cover plate (6a) extending parallel to said sides (2, 4) adjacent to one long side of the storage unit (1), and a rail system with a number of parallelly mounted transverse rails (5a) between the two long sides (2, 4), and the lids (10a, 10b) are displaceably mounted between two adjacent rails (5a) of the rail system, said rails (5a) comprising separate tracks for the lids (10a, 10b) in each of the rows, whereby the lids (10a, 10b) in the rows are displaceable in a direction perpendicular to the long sides (2, 4). Hereby, good access may be provided along the entire length without creating a pump effect by operating the lids (10a, 10b). In addition, good visual access is provided for easy examination of the contents of the merchandising unit (1), since the cover according to the invention provides for the possibility of simultaneous opening of a large percentage of the total top of the merchandising unit (1). <IMAGE>
Patent NO-322118-B1 (NO)
Title: Optisk kabelenhet
Inventor: BIRKELAND TOM HARALD
IPC: B23K26/244
Filed: 2005-04-01
Abstract: Det er tilveiebragt en optisk kabelenhet omfattende et metallrør med en langsgående lasersveist skjøt og minst en optisk bølgeleder i det innvendige av metallrøret, metallrøret består av to lag, omfattende det første indre laget (13c) består av kobber og det andre ytre laget (13b) består av austenittisk stål og at den langsgående skjøten (13a) av begge lag (13b, 13c) er lasersveist og at skjøtene til lagene (13b, 13c) er innrettet oppå hverandre, lasersveisingen har blitt gjort ved hjelp av en C02-laser. Den optiske kabelenheten er kjennetegnet ved at metallrøret (13) består av et laminat av austenittisk stål og kobber. Det er tilveiebragt en fremgangsmåte for fremstilling av en optisk kabelenhet omfattende et metallrør med en langsgående sveist skjøt og minst en optisk bølgeleder i det indre av metallrøret, der et metallbånd er kontinuerlig utformet til et rør med et spor, den minst ene optiske bølgelederen puttes kontinuerlig inn i det fortsatt åpne sporet i røret og sporet lukkes med en lasersveiseenhet. Fremgangsmåten er kjennetegnet ved at laminatbåndet med et lag av austenitisk stål og et lag av kobber er dannet til et rør med et spor, og at skjøten av røret med sporet sveises med en C02-laser, hvorved varmen som bringes inn i skjøten i laget med austenitisk stål forårsaker sveising av skjøten i kobberlaget.
Patent NO-331985-B1 (NO)
Title: Fremgangsmate for fremstilling av 5-[(R)(5,6-dietyl-indan-2-ylamino)-1-hydroksyetyl]-8-hydroksy-(1H)-kinolin-2-on-salt som er nyttig som adrenoreseptoragonist, samt mellomprodukter
Inventor: LOHSE OLIVIER
IPC: C07D215/26
Filed: 2005-09-26
Abstract: En fremgangsmåte for fremstilling av 5-[(R)-2-(5,6-dietyl-indan-2-ylamino)-l-hydroksy-etyl]-8-hydroksy-(1H)-kinolin-2-on salt. Fremgangsmåten omfatter dannelse av et syresalt av 5-[(R)-2-(5,6-dietyl-indan-2-ylamino)-l-hydroksy-etyl]-8-substituert oksy-(1H)-kinolin-2-on; og omdanning av syresaltet til et salt av 5-[(R)-2-(5,6-dietyl-indan-2-ylamino)-l-hydroksy-etyl]-8-hydroksy-(1H)-kinolin-2-on uten å isolere den frie basen av 5-[(R)-2-(5,6-dietyl-indan-2-ylamino)-l-hydroksy-etyl]-8-hydroksy-(1H)-kinolin-2-on.