baber/WOPTO huggingface dataset:
Patent NZ-510253-A (NZ)
Title: Neuroprotection
Inventor: SCHEEPENS ARJAN
IPC: A61K38/27
Filed: 1999-09-03
Abstract: The neuroprotection and medicaments for use therein.  Neuroprotection is induced by activation of neural growth hormone receptors, primarily using medicaments comprising growth hormone, functionally equivalent analogs of growth hormone or functionally equivalent ligands.  Such medicaments may also include one or more neuroprotective agents.
Patent NZ-515123-A (NZ)
Title: Drive device for a washing machine
Inventor: HEYDER REINHARD
IPC: D06F37/30
Filed: 2000-05-16
Abstract: A drive device for a washing machine comprises a washing-drum mounted floatingly by means of a horizontal or nearly horizontal shaft which is driven directly by flat electric motor mounted on the rear face of the wash-water container, with the stator being connected to a stiff support. The stator and rotor of the electric motor is connected to each other by a bearing arrangement and are removable together from the washing machine. The shaft is mounted in bearings either in the rear wall or in the support-part mounted on the rear wall. The shaft has a journal which projects from the rear wall of the wash-water container or from the support-part and which is surrounded by a hallow shaft formed by the rotor of the electric motor and which the stator and the rotor of the electric motor can be pushed together be pushed onto.
Patent NZ-516411-A (NZ)
Title: Human monoclonal antibody against a costimulatory signal transduction molecule AILIM and pharmaceutical use thereof
Inventor: TSUJI TAKASHI
IPC: C07K16/18
Filed: 2001-05-15
Abstract: Immunization of human antibody-producing transgenic mice, which have been created using genetic engineering techniques, with activation inducible lymphocyte immunomodulatory molecule (AILIM) molecule as an antigen resulted in various human monoclonal antibodies capable of binding to AILIM and capable of controlling a variety of biological reactions (for example, cell proliferation, cytokine production, immune cytolysis, cell death, induction of antibody-dependent cellular cytotoxicity (ADCC), etc.) associated with AILIM-mediated costimulatory signal (secondary signal) transduction. Furthermore, it has been revealed that the human monoclonal antibody is effective to treat and prevent various diseases associated with AILIM-mediated costimulatory signal transduction, being capable of inhibiting the onset and/or advancement of the diseases.
Patent NZ-518964-A (NZ)
Title: Immunotherapy to enhance the response of T cells to tumor cells by inhibiting expression of the Notch ligand
Inventor: LAMB JONATHAN ROBERT
IPC: A61K39/00
Filed: 2000-11-17
Abstract: Described is the use of a T cell having enhanced reactivity towards a tumor cell for the preparation of a medicament for the therapeutic and/or prophylactic treatment of a malignancy. The T cell is prepared by exposing a T cell obtained from a patient to an agent which is capable of reducing or preventing expression or interaction of an endogenous Notch or Notch ligand in the cell. The T cell comprises a T cell receptor specific for a tumour antigen expressed by the tumour cell. The T cell can also be prepared by exposing an antigen presenting cell (APC) obtained from a tumour to an agent which is capable of reducing or preventing expression or interaction of an endogenous Notch or Notch ligand in the T cell when the T cell is contacted with the APC or by exposing a tumour cell obtained from a patient with to an agent which is capable of reducing or preventing expression or interaction of an endogenous Notch or Notch ligand in the T cell when the T cell is contacted with the tumour cell. Also described is an anti-tumor vaccine comprising a tumour antigen and an agent which is capable of reducing or preventing interaction, expressing or processing of Notch or a Notch ligand.
Patent NZ-520120-A (NZ)
Title: New octahydro-2H-pyrido[1,2-a]pyrazine compounds, a process for their preparation and pharmaceutical compositions containing them
Inventor: GOLDSTEIN SOLO
IPC: A61K31/5025
Filed: 2002-07-11
Abstract: Disclosed are compounds of formula (I), for which the substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of diseases mediated by an antagonist of type H3 central histamine receptors.
Patent NZ-522783-A (NZ)
Title: Wet milling process for pharmaceuticals with agitator or chamber having nylon with internal lubricant
Inventor: HOLLAND SIMON JOSEPH
IPC: A61K9/14
Filed: 2001-06-22
Abstract: A process for preparing a finely divided preparation of a drug substance comprising wet milling a suspension of the drug substance in a mill having at least one chamber and agitation means, said chamber(s) and/or said agitation means comprising nylon, wherein the nylon comprises one or more internal lubricants results in finely divided preparations of a drug substance in which the level of grinding media contamination and process contamination are reduced.
Patent NZ-524157-A (NZ)
Title: Osteoimplant and method of making same
Inventor: EDWARDS JEAN T
IPC: A61F2/46
Filed: 2001-07-19
Abstract: An osteoimplant which comprises a shaped, coherent three-dimensional porous matrix of elongate demineralized bone particles, wherein the matrix possesses a bulk density of lower than about 0.3 g/cm3; a method of fabricating an osteoimplant comprising: (a) providing a quantity of elongate demineralized bone particles; (b) mixing the elongate demineralized bone particles with a wetting agent comprising water to provide a liquid composition containing from about 5 to about 40 volume percent swollen, hydrated elongate demineralized bone particles; (c) placing the liquid composition in a mould; and (d) heating the composition in the substantial absence of pressure at a temperature above 35°C for a period of time sufficient to remove water present in the wetting agent to provide an osteoimplant comprising a shaped, coherent, three-dimensional porous matrix of elongate demineralized bone particles, wherein the matrix possesses a bulk density of lower than about 0.3 g'cm3; a method of repairing and/or treating bone comprising implanting the osteoimplant in a non-human; and a spinal fusion method using the osteoimplant.
Patent NZ-524164-A (NZ)
Title: Oral solid dose vaccine
Inventor: VANDE-VELDE VINCENT
IPC: A61K39/39
Filed: 2001-08-14
Abstract: Vaccine formulations suitable for oral administration are described. The vaccine formulations are in a solid form comprising antigen and a suitable excipient, which after insertion into the mouth, rapidly dissolve in saliva. Specifically, the solid form may consist of a cake of vaccine which is formed from a liquid solution or suspension by sublimation. Preferred vaccines are those containing antigens which are derived from pathogens that normally infect or invade the host through a mucosal membrane, or those vaccines that further comprises an antacid.
Patent NZ-532011-A (NZ)
Title: Hydraulic brake circuit
Inventor: NOWAK STAN
IPC: B60T7/12
Filed: 2002-08-30
Abstract: A hydraulic brake system (10) for operating service brakes (12, 14) and (16) is provided with first and second master cylinders (20, 22) which feed into input ports (26) and (28) of a valve (24). Duplicate hydraulic circuits (30) and (34) are coupled with respective output ports (32) and (36) of the valve (24). Each of the hydraulic circuits (30) and (34) also includes a common circuit portion comprising a selective valve (44) and common line (42) leading to brake (16). The system (10) also includes hand brake (18) which is electrically deployed and manually released. A controller (52) controls operation of the system (10) to switch between master cylinders (20) and (22), and hydraulic circuits (30) and (34), depending on sensed fluid pressure. In the event of switching both master cylinders (20) and (22) to one of the hydraulic circuits (30) or (34), and a controller continuing to sense low fluid pressure, the common circuit is isolated. In the event of a sensed complete hydraulic failure, the controller (52) automatically deploys the park brake (18).
Patent NZ-539764-A (NZ)
Title: Thermosetting powder coating compositions comprising a co-reactable mixture
Inventor: MOENS LUC
IPC: C09D167/02
Filed: 2003-10-29
Abstract: Disclosed herein is a thermosetting powder coating composition comprising a co-reactable blend of (i) 5 to 50 weight percent of at least one of glycidyl group containing acrylic copolymer chosen between glycidyl group containing acrylic copolymers (A) having a glass transition temperature in the range of from +45 to +100 DEG C and a number average molecular weight in the range of from 2000 to 5000, glycidyl group containing acrylic copolymers (A') having a glass transition temperature in the range of from -50 to+ 40 DEG C, and their mixtures; (ii) 5 to 90 weight percent of at least one carboxylic acid group containing polyester chosen between carboxylic acid group containing polyesters (B) having an acid number in the range of from 15 to 100 mg KOH/g and a glass transition temperature in the range of from +45 to +100 DEG C, carboxylic acid group containing polyesters (B') having an acid number in the range of from 15 to 100 mg KOH/g and a glass transition temperature of from -50 to +40 DEG C, and their mixtures; (iii) 5 to 50 weight percent of at least one carboxylic acid group containing acrylic copolymer chosen between carboxylic acid group containing acrylic copolymers (C) having a glass transition temperature in the range of from +45 to +100 DEG C, an acid number of from 10 to 90 mg KOH/g and a number average molecular weight in the range of from 2000 to 5000, carboxylic acid group containing acrylic copolymers (C') having a glass transition temperature in the range of from -50 to +40 DEG C, an acid number of from 10 to 90 mg KOH/g, and their mixtures; the weight percentages being calculated on the whole of the components (A), (A'), (B), (B'), (C) and (C'); and (iv) a thermosetting catalyst (D); provided that at least one of the low glass transition temperature polymers (A'), (B') and (C') is present in the composition. These thermosetting powder coatings are particularly designed for coating heat-sensitive substrates and produce a finish which exhibits reduced gloss.
Patent NZ-542054-A (NZ)
Title: Beverage mixer
Inventor: DANIELS THOMAS E
Filed: 2001-11-13
Abstract: A beverage mixer, comprising: a) a base (18) including a motor (22) for turning a drive mechanism (26) extending from the base; b) a container (14) removably locatable on the base and including a mixing assembly (38) rotatably disposed therein, the mixing assembly being engagable by the drive mechanism when the container is disposed on the base; c) a lid (54) removably disposed on the container, having an opening (58); d) a spout (80), operably coupled to the container or to a bottom part or portion (46) connectable to the container to dispense contents thereof, the spout including a valve (88) disposed on the spout and operable to enable contents of the container to flow through the spout; and e) the beverage mixer comprising a cup-receiving indentation (100) formed in the base as part of the base configured or provided to provide a space to enable a cup to be readily received under the spout, the spout being alignable with the cup-receiving indentation when the container is disposed on the base.
Patent NZ-545823-A (NZ)
Title: Device for applying paint
Inventor: SCHULTZ IAN
Filed: 2006-03-10
Abstract: A device with an application surface defined by outer portions of porous material adapted to hold and dispense a product (e.g. paint) onto a substrate during compression. Grooves are provided between adjacent portions for holding additional product for simultaneous application to a substrate and for receiving further product from the portions during compression. The porous material has a cell size of at least in the order of 3 ppi.
Patent NZ-547565-A (NZ)
Title: Substituted arylpyrazoles as parasiticidal agents
Inventor: BILLEN DENIS
IPC: A61K31/415
Filed: 2004-12-15
Abstract: Disclosed is a range of 1-aryl-4-cyclopropylpyrazoles of formula I in which there is at least one fluorine attached to the cyclopropyl ring, to compositions comprising such compounds, processes to their synthesis and their use as parasticides.
Patent NZ-550466-A (NZ)
Title: Method and device for content-based billing in IP-networks
Inventor: STADELMANN TONI
IPC: G06Q20/00
Filed: 2004-05-12
Abstract: A method and system for content-based billing in IP-networks is provided. The method includes the steps of: carrying out and transmitting to a control gateway module the authentication and/or service authorisation of an IP-node based on the IMSI of a SIM card of the node for HLR and/or VLR of a GSM network, guiding the access of the IP node to the content of a network content provider thorough said control gateway module, controlling involved costs by means of the module on the base of the access target address, detecting call detail records according to the IP-node services by a core engine module, detecting at least the identity of the IP-node and/or the time and/or a provider of the required services by means of said call detail records during access to the control gateway module, transmitting said data to the billing module and computing the call detail records and/or clearing data based thereon and/or TAP files through the billing system of a service provider or a financial institution.
Patent NZ-552348-A (NZ)
Title: Water saving device with water diverted until desired temperature attained
Inventor: HONEYCHURCH LINDY
IPC: G05D23/02
Filed: 2005-07-15
Abstract: A water saving device (100) for use in a hot water system to recover an initial volume of cold water when a hot water tap is turned on. The device has an inlet (103) for receiving water piped from a water heater, a primary outlet (104) for delivering hot water to a tap, and a by-pass outlet (109) through which any cooled water is diverted by a thermally actuated (115) shuttle valve (112). The device also includes a secondary valve (130) for closing off the by-pass outlet (109) when the water pressure downstream of the primary outlet (104) is high (such as when the down stream hot water delivery tap is closed) and opening the by pass outlet (109) when the water pressure downstream of the primary outlet (104) is low (such as when the downstream hot water delivery tap is opened.
Patent NZ-555157-A (NZ)
Title: Enclosed fence/railing set
Inventor: LIEFKE NORMAN WILLIAM
Filed: 2007-05-15
Abstract: Disclosed is an enclosed fence/railing set, and more particularly an extruded aluminium enclosed fence/railing set assembled by matching grooves. It can be flexibly assembled according to various venues, and it is equipped with stakes that hold tightly to the ground. It can be easily transported and assembled.
Patent NZ-555256-A (NZ)
Title: Housing, typically similar to credit card size, with compressed gas container, medicament container(s) for user to inject medicament
Inventor: EDWARDS ERIC SHAWN
IPC: B67D7/02
Filed: 2004-11-22
Abstract: Certain exemplary embodiments comprise an apparatus, comprising: a compressed gas container; a plurality of vials adapted to store a liquid medicament, each vial defining a longitudinal axis, the longitudinal axes of the plurality of vials parallel and non-co-axial, the plurality of vials fluidly coupleable to an actuating portion of a contents of the gas container; and a plurality of pistons, each piston adapted to move within a corresponding vial from the plurality of vials, the plurality of pistons adapted to, in response to discharge of the actuating portion of the contents of the compressed gas container, transfer at least a portion of the liquid medicament from the plurality of vials and through a needle that is extendable into a patient.
Patent NZ-564796-A (NZ)
Title: Water treatment system including foam block
Inventor: JOWETT E
Filed: 2007-12-24
Abstract: The water to be treated might be river water which needs to be clarified, or might be septic tank effluent which needs to have its BOD and dissolved organics content diminished, and its ammonium oxidised. Treatment is done by passing the water through a block of soft open-cell foam. The block of foam is rectanguloid in its basic form. The block of foam is housed in a watertight box. The rectanguloid form enables minimal hydraulic heads, and is simple and cheap to manufacture and install.
Patent NZ-567234-A (NZ)
Title: Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides
Inventor: TIAN FENG
IPC: C07C249/08
Filed: 2006-11-08
Abstract: Disclosed is a reaction mixture comprising a compound comprising an aromatic ketone moiety, a compound comprising a hydroxylamine moiety, and an accelerant selecting from the group consisting of bifunctional aromatic amines, oxoamine derivatives, and compounds having a structure selected from group I wherein Rx, Ry and Rz are selected from the group consisting of: Lx-H, Lx-alkyl, Lx-aryl, Lx-heteroaryl, Lx-alkenyl, Lx-alkynyl, Lx-alkoxy, and Lx-alkylamine, where Lx is a bond, C(=O), C(=NH), C(=NH)-NH, SO, and SO2. Further disclosed is a method for derivatizing an amino acid comprising contacting an amino acid in the presence of an accelerant as defined within the claims.
Patent NZ-572098-A (NZ)
Title: Beverage container with internal pressure system and an irreversible tapping device
Inventor: BAX BART JAN
IPC: B67D1/04
Filed: 2007-03-19
Abstract: A beverage container containing a carbonated beverage is disclosed. The container has an inner space, at least partly filled with the carbonated beverage. A valve assembly (15) is attached to the container, in particular a top surface (4). The valve assembly (15) comprises a valve body (21) biased to a closed position against a valve seat (20). A pressure control device is provided inside which has a reservoir, filled with a pressure gas in communication with the inner space, via a pressure control device. An operating device (40) when used by pressing moves the valve body (21) away from the valve seat (20), dispensing the beverage though a beverage dispensing channel (48, 53) and is provided with means (64) for irreversibly maintaining the valve (15) assembly in an opened position.
Patent NZ-574383-A (NZ)
Title: Intelligent Yogurt Maker
Inventor: CLIFFORD LEONARD EDWARD
IPC: A01J11/00
Filed: 2009-01-26
Abstract: An easily adjustable single application portable micro controlled yoghurt maker machine is disclosed. The portable micro controlled yoghurt maker machine is programmed via a computer or the internet allowing the yoghurt maker to manufacture or produce small consistent batches of yoghurt in a pot or vessel with different cycles that the operator can select depending on what style and taste of yoghurt he wants to obtain from the culture. The yoghurt maker once programmed achieves this by monitoring the temperature and time and making adjustments according to algorithms but no agitation is required so that once the process has been initiated the microcontroller is responsible for reading and adjusting the temperature by turning the heating element on and off at the right time by calculating where the product is in the manufacturing cycle.
Patent NZ-577098-A (NZ)
Title: Intra-vascular kidney gene therapy with plasmid encoding bmp-7
Inventor: FISHER LAURENT BERNARD
IPC: A61K38/18
Filed: 2007-11-09
Abstract: Disclosed is a recombinant plasmid vector comprising a nucleic acid sequence encoding a feline BMP-7 polypeptide operatively linked to a promoter, wherein the BMP-7 polypeptide is as defined in the specification. The disclosed plasmid vector is used in treating or preventing renal failure in a non-human subject.
Patent NZ-585877-A (NZ)
Title: Heat treated bacterins, and emulsion vaccines prepared from such heat treated bacterins
Inventor: GOODYEAR MARK DAVIS
IPC: A61K39/02
Filed: 2008-12-04
Abstract: Provided is a vaccine comprising: a) an emulsion comprising an oil and one or more emulsifiers, b) a heat treated bacterin comprising a suspension of killed bacteria, wherein - the killed bacteria are Leptospira species, - the bacterin was heated to a temperature of about 35 to about 80°C for about 20 minutes to about 24 hours, - the bacterin has acceptable antigenic activity, - the bacterin has a lipase activity of 50% or less than the lipase activity of the bacterin before the heat treatment; and c) 1 to 13 porcine disease causing viruses selected from the group consisting of Porcine Adenovirus, Porcine Circovirus, Porcine herpes viruses, Pseudorabies virus, Classical swine fever virus, Porcine epidemic diarrhea virus, Porcine hemagglutinating encephalomyelitis virus, Porcine parvovirus, Porcine Respiratory Corona virus, Porcine Reproductive and Respiratory Virus, Swine Influenza, Transmissible gastroenteritis virus, and Vesicular stomatitis virus; wherein said vaccine has increased stability when compared with a vaccine comprising non-heat treated bacterin.
Patent NZ-590297-A (NZ)
Title: 2-Alkylamino-7,8-dihydropteridin-6(5H)-one and 2-alkylamino-8,9-dihydro-5H-pyrimido[4,5-b][1,4]diazepin-6(7H)-one derivatives
Inventor: CHARRIER JEAN-DAMIEN
IPC: A61K31/4985
Filed: 2009-06-23
Abstract: Disclosed are 2-alkylamino-7,8-dihydropteridin-6(5H)-one and 2-alkylamino-8,9-dihydro-5H-pyrimido[4,5-b][1,4]diazepin-6(7H)-one derivatives as represented by the general formula (I) or a pharmaceutically acceptable salt thereof, wherein: Y is O or NR9; R1 is optionally substituted cycloalkyl or optionally substituted heterocycloalkyl; R2 is H, alkyl, or cycloalkyl; each of R3 and R4 is independently H, alkyl, cycloalkyl, aryl, or heteroaryl; or R3 and R4 together with the carbon atom to which they are attached, form a cycloalkyl; each of R5 and R6 is independently H, alkyl, cycloalkyl, aryl, or heteroaryl; R7 is H or alkyl, cycloalkyl, aryl, heteroaryl, or heterocyclyl, any of which is optionally substituted; or R8 is optionally substituted alkyl; R9 is H or alkyl; or R2 and R9 together with the atoms to which they are attached, optionally form a 5- to 8-membered monocyclic ring containing additional 0 to 2 hetero atoms each independently selected from O, N, and S, wherein said monocyclic ring is optionally substituted with 0 to 4 groups each independently being alkyl, halo, alkoxy, or hydroxy; and q is 0 or 1. Representative compounds include 9-cyclopentyl-5,7,7-trimethyl-2-(1-(1-methylpiperidin-4-yl)ethylamino)-8,9-dihydro-5H-pyrimido[4,5-b][1,4]diazepin-6(7H)-one, 2-(1-cyclohexylethylamino)-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one, 2-(4-(1-(8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylamino)ethyl)piperidin-1-yl)acetonitrile. Further disclosed is a pharmaceutical composition comprising a compound as defined above and a pharmaceutically acceptable carrier, adjuvant, or vehicle, for treating a proliferative disorder, a neurodegenerative disorder, an autoimmune disorder, an inflammatory disorder, or an immunologically mediated disorder in a patient, and particularly for treating melanoma, leukemia, lymphoma or cancer.
Patent NZ-591969-A (NZ)
Title: Combination of anticholinergics, glucocorticoids, beta2-adrenoceptor agonists, PDE 4 inhibitor and antileukotriene for the treatment of inflammatory diseases
Inventor: MAUS JOACHIM
IPC: A61K31/167
Filed: 2006-12-01
Abstract: Combination of R,R-glycopyrrolate, formoterol and a glucocorticoid selected from budesonide and mometasone or their physiologically acceptable salts is disclosed, wherein said combination is suitable for the treatment of inflammatory diseases selected form the group comprising respiratory diseases selected from asthma or COPD, rheumatism or auto-immune diseases selected from rheumatoid arthritis, glomerulonephritis, multiple sclerosis, Crohn's disease, ulcerative colitis, systemic lupus erythematosus or psoriasis.