baber/WOPTO huggingface dataset:
Patent CA-2122374-A1 (CA)
Title: Oral pharmaceutical composition containing polyethylene glycol immunoglobulin conjugate for reconstitution of secretory immunity and method of reconstituting secretory immunity
Inventor: CUNNINGHAM-RUNDLES CHARLOTTE
IPC: A61K47/48
Filed: 1992-10-15
Abstract: Polyethylene glycol serum immunoglobulin conjugates exhibit substantial resistance to degradation by intestinal enzyme while retaining their immuno-activity. Thus, PEG-IgG or PEG-IgA conjugates can be used as orally administered therapeutics to treat patients with gastrointestinal immunodeficiency to reconstitute secretory immunity. Preferred conjugates are made by reacting activated PEG  and IgG in ratios of from 1:5 to 1:1000 such that less than about 27 % of the IgG lysine residues are bonded to the PEG. The conjugates are advantageously formulated into a pharmaceutical composition comprising the conjugate and a pharmaceutically acceptable oral carrier. Particularly for administration to infants, a preferred oral carrier is milk.
Patent CA-2123304-A1 (CA)
Title: Needle assembly holder with rotatable safety sheath member and method of effecting proper alignment of a cannula
Inventor: HOLLISTER WILLIAM H
IPC: A61M5/31
Filed: 1992-12-17
Abstract: The needle assembly holder (2) of the present invention has mounted about its receptacle end (6) a rotatable safety sheath (20) so that irrespective of how the tip (28T) of the cannula (28) of the needle assembly (30) is oriented with respect to the holder (2), the user can nonetheless obtain an unobstructed view of the tip (28T) of the cannu-la (28) by rotating the safety sheath (20) out of her line of sight. Friction drag is pro-vided between the receptacle end (6) of the needle assembly holder and the safety sheath (20) so that the safety sheath (20) would not freely rotate about the needle as-sembly holder (2) absent a rotation force applied thereagainst.
Patent CA-2123762-A1 (CA)
Title: Method and apparatus for discharging a reactor
Inventor: RUELLE JEAN-JACQUES
IPC: B65G53/08
Filed: 1994-05-17
Abstract: Process for discharging a reactor by means of a device including at least one densification zone (3) in which the volume available for the powder is decreased without, however, compacting it. Device for discharging a reactor, including at least one densification zone. <IMAGE>
Patent CA-2126016-A1 (CA)
Title: Disposable ear syringe
Inventor: DWORAK ANDREW
IPC: A61H33/00
Filed: 1994-06-16
Abstract: A hand-held  device  for  syringing  wax  or  other  foreign material  from  ears  consisting  of  a  tip,  pump  mechanism activated by a trigger, and a length of tubing to be immersed in any suitable container of water.
Patent CA-2126527-A1 (CA)
Inventor: BURNS JAMES A
IPC: A61B5/154
Filed: 1994-06-22
Abstract: A combination stopper and shield closure for sealing the open end of an evacuated body fluid collection tube. The stopper is headless and includes a well in its top surface with an undercut at its base. The shield includes a plurality of flexible fingers extending from its top surface, each finger including a cleat at its proximal end for engaging with the undercut in the stopper. The interaction between the cleats and the undercut serve to securely hold the stopper within the shield and eliminate compression forces being applied to the stopper by the shield. In addition, the base of the well is convex to direct any residue body fluid away from the center of the well towards the undercut and minimize residue build-up, and the bottom portion of the stopper is concave to reduce the thickness of the stopper's diaphragm and reduce penetration force.
Patent CA-2126849-A1 (CA)
Title: Polylactide Containing Hot Melt Adhesive
Inventor: IOVINE CARMINE P
IPC: C09J201/00
Filed: 1993-09-20
Abstract: Hot melt adhesive compositions are prepared from 20 to 98% by weight of a polylactide homo- or copolymer containing at least 20 molar percent of the lactide component; 2 to 80% by weight of a polar tackifier having a Ring and Ball softening point (as described by ASTM E-26) greater than about 60°C; 0 to 50% by weight of a plasticizer; 0 to 30% by weight of a wax diluent; 0-3% by weight of a stabilizer; and 0-20% of a polymer.   By utilizing   a   naturally   occurring,   thermoplastic, biodegradable  copolymer  as  the  base  polymer,  these adhesives advance the state of the art of hot melt adhesives by alleviating the dependence on petroleum based materials and by allowing for the development of hot melt adhesives which either degrade naturally after coming  in  contact  with  the  soil  or  which  can  be composted.
Patent CA-2127573-A1 (CA)
Title: Vasotonic treatment for migraines
Inventor: GEDYE ANGELA C
IPC: A61K31/445
Filed: 1994-07-07
Abstract: A novel composition of five extant agents was hypothesized, tested, and confirmed for alleviating migraine headaches.  The hypothesis was based on ways to correct three features of migraines--falling blood levels of serotonin, vasodilatation, and inflammatory response--using already existing agents.  The composition successfully aborted migraines within 30 to 60 minutes, sometimes requiring a repeat four hours later if symptoms returned.  Two of the five components--acetylsalicylic acid and caffeine--are already used for treating headaches, yet it was the combination of these two and three other agents--niacin, calcium, and L-tryptophan--that successfully alleviated migraines.  Once taken, subjects are not to consume high-potassium food or drinkfor several hours as potassium causes vasodilatation, militating against effortsto enhance vasoconstriction.  Other migraine medications risk rebound headaches,serious side effects like cardiac ischemia or paresthesia in the extremities, and drug addiction (some contain a barbiturate and/or narcotic).  The five components risk only minor side effects and are used at low-to-very-low doses, further reducing the risk of adverse effects.  Apart from occasional flushing from niacin, no side effects or rebound headaches have been reported in migraineurs using this from 1 - 2 1/2 years.  No one has previously reported combining these five agents intentionally or serendipitously.  No one has reported using tryptophan or calcium for headaches, so the combination of all five agents was not obvious.  This migraine treatment resulted from scientific hypothesis-testing, not from serendipity or an "obvious" combining of agents.
Patent CA-2127826-A1 (CA)
Title: Liquid-vapour contact apparatus
Inventor: LAVIN JOHN T
IPC: F25J3/04
Filed: 1994-07-12
Abstract: ABSTRACT LIQUID-VAPOUR CONTACT APPARATUS Apparatus comprising a liquid-vapour contact column 2 houses an array of vertically spaced liquid-vapour contact trays 6a, 6b and 6c, and an arrangement of downcomers 8a, 8b and 8c that conduct liquid from tray-to-tray down the array. In a vapour space between the trays 6b and 6c there is a liquid vapour disengagement device 34b having vapour passages therethrough and defining a surface or surfaces for the flow thereacross of any liquid disengaged from vapour ascending the column. The device 34b is typically provided by a sheet of expanded metal and has an outlet edge 44 in liquid flow communication with the tray 6c via the downcomer 8c.
Patent CA-2128354-A1 (CA)
Title: Pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases including ulcer
Inventor: SZIRT ENIKOE
IPC: A61K31/15
Filed: 1994-07-19
Abstract: Abstract Pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases including ulcer The invention refers to pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases including ulcer and a method for the treatment of such diseases.    The pharmaceutical composition of the invention comprises as active ingredient a cyclic ketone derivative of the formula I                           (I) wherein R and R1 mean independently hydrogen or halo;          R° stands for hydrogen or a C1-4 alkoxy group; with the proviso that at least one of R, R1 and R° is hydrogen;          R2 and R3 independently represent hydrogen; a straight or branched chain C1-8 alkyl optionally substituted by a dimethylamino group; a C2-6 alkenyl or a C3-7 cycloalkyl group; or R2 and R3 together with the adjacent nitrogen atom form a 6--membered heterocyclic group containing an additional nitrogen atom that may bear a phenyl group optionally substituted by a C1-4 alkoxy group; or its stereoisomer or optical isomer or a possible mixture thereof, or a pharmaceutically acceptable acid addition salt or quaternary ammonium derivative thereof in admixture with carrier(s) commonly used in pharmaceutical compositions.    The method of the invention for the treatment of gastrointestinal diseases comprises administering an effective non-toxic dose of a compound of the formula I or a stereoisomer or optical isomer or a possible mixture thereof, or a pharmaceutically acceptable acid addition salt or quaternary ammonium derivative thereof to a patient suffering from gastro-intestinal disorders.
Patent CA-2129568-A1 (CA)
Title: Fibre reinforced thermoplastic sheet
Inventor: JANSZ JUST J C
IPC: C08J5/04
Filed: 1994-08-05
Abstract: Abstract A glass mat reinforced thermoplastic semi-finished sheet material comprising thermoplastic resin and at least two needled continuous and/or chopped glass fibre strand mats is disclosed as well as a method for its manufacturing and its use. Each of said glass mats is needled from the two sides in an asymmetrical way, so that the number of fibre ends protruding from the two ma-jor mat surfaces are practically the same, but the length of said fibre ends protruding from the first major sur-face is substantially longer than the length of the fibre ends protruding from the second opposite major surface. Said glass mats are impregnated with thermoplastic resin, having either their first major surfaces directed towards the outside surface of said thermoplastic sheet, for max-imum mouldability, or having their second major surfaces directed towards the outside surface of said thermoplas-tic sheet, for maximum surface quality of the moulded part.
Patent CA-2130041-A1 (CA)
Inventor: SYMONS MICHAEL W
IPC: E04C2/296
Filed: 1994-08-12
Abstract: ABSTRACT            A method of making a composite board having a front and a back in a mould includes the steps of: (a) applying a layer of a first composition comprising a thermosetting resin and a catalyst for the thermosetting resin, to the surface of the mould; (b) allowing the thermosetting resin to polymerize to form the front of the composite board; (c) applying a layer of a connecting composition comprising an adhesive or a second composition comprising a thermosetting resin and a catalyst for the thermosetting resin, to the inner surface of the front of the composite board in the mould; (d) placing a structure comprising one or more laminae, each lamina comprising first and second sheets of a natural fibre material and a corrugated sheet or a cellular core of a natural fibre material sandwiched between the first and second sheets, the lamina having been impregnated with a third composition comprising a thermosetting resin, an extending liquid for the thermosetting resin and a catalyst for the thermosetting resin, the thermosetting resin having been polymerized, on the connecting layer of step (c); and (e) allowing the connecting composition to set to join the structure to the front of the composite board to form the composite board, and removing the composite board from the mould. In another embodiment of the method, a layer of a fibrous reinforcing material wetted with a fourth composition comprising a thermosetting resin and a catalyst for this thermosetting resin may be interposed between the layer of the first composition and the structure, using a layer of a connecting composition, to join the various layers together. The method produces a composite board which may be used as a door or as a building board.
Patent CA-2131362-A1 (CA)
Inventor: KOTAKI YUJI
IPC: H01S5/12
Filed: 1990-07-13
Abstract: A distribution feedback laser diode, comprises a substrate, a waveguide layer provided on the substrate, an active layer provided on the waveguide layer, a diffraction grating provided at an interface between the substrate and the waveguide layer for reflecting an optical radiation formed in the active layer back and forth, a clad layer provided on the active layer for confining the optical radiation within the active layer, a plurality of segmented electrodes provided on the top surface of the clad layer along an elongated direction of the laser diode for injecting the carriers into the active layer, wherein at least one of the segmented electrodes is provided in correspondence to a part of the active layer in which the optical radiation formed in the active layer has a maximum intensity level, and a backside electrode provided at the bottom surface of the substrate for injecting the carriers into the active layer through the substrate.
Patent CA-2134527-A1 (CA)
Title: Dental impression tray
Inventor: SCHULDT HARRY J
IPC: A61K6/90
Filed: 1994-10-27
Abstract: A dental impression tray having a rough textured surface which provides a multiplicity of pits made up of valleys and peaks, holes that don't penetrate through the tray, cavities, craters, crevices, ledges and/or undercuts which retain and/or stabilize the impression material. The rough textured surface of the handle provides a non- slip surface for a gloved hand.
Patent CA-2135383-A1 (CA)
Inventor: KAO WEI-WEN
IPC: G01C17/38
Filed: 1993-05-12
Abstract: The invention provides a direction sensor and a method of calibrating a direction sensor having a relative heading sensor (14) and an absolute heading sensor (16). The method allows calibration (22) of both the relative heading sensor (14) and the absolute heading sensor (16) at the same time, by taking advantage of the known angular relationship between maxima and minima on the measurement curve of the absolute heading sensor (16). Such maxima and minima are found by rotating the sensors (12-18) through and angle of at least 360°, reading the absolute and relative heading. sensor outputs., at numerous points and comparing each successive output. The relative heading sensor output at the minimum is substracted from that at the maximum, and the difference divided by the known angle to arrive at a conversion constant for the relative heading sensor (14). The center and radii of the measurement curve of the absolute heading sensor (16) may be found by determining the maxima and minima of the curve in two perpendicular directions.
Patent CA-2135542-A1 (CA)
Title: Shaped body having a high silicon dioxide content and process for producing such shaped bodies
Inventor: MORITZ STEPHAN
IPC: G01J1/42
Filed: 1994-11-10
Abstract: A shaped body of amorphous silicon dioxide, which has a chemical purity of at least 99.9 % and a cristobalite content of at most 1% and which is impermeable to gas, is known. To provide shaped bodies of amorphous silicon dioxide which have a high precision, which can be small or large in size and of simple to complicated shape, which have a chemical purity of at least 99.9 %, are impermeable to gas above wall thicknesses of 1 mm, which have a high cold flexural strength, low thermal conductivity and low radiation of heat, which are thermal shock resistant and can be exposed repeatedly or also long-term to temperatures in the range from 1000 to 1300°C and which can be welded in a sharply delineated manner without spreading joins and which have a low spectral transmission from the ultraviolet to the middle infrared spectral region, the shaped body is opaque, contains pores, at a wall thickness of 1 mm has a direct spectral transmission which is virtually constant in the wavelength range from .lambda. = 190 nm to .lambda. = 2650 nm and is below 10 %, and it has a density which is at least 2.15 g/cm3. A process for producing such shaped bodies is given.
Patent CA-2135858-A1 (CA)
Title: Artificial neuron using adder circuit and method of using same
Inventor: WANG SHAY-PING T
IPC: G06N3/063
Filed: 1994-11-15
Abstract: An artificial neuron, which may be implemented on an integrated circuit, has only one significant processing element in the form of an adder.  Inputs are first fed through gating functions to produce gated inputs.  These gated inputs are then added together to produce a sum which is added to a weight to produce the neuron output.
Patent CA-2136431-A1 (CA)
Inventor: HAN HAK-RHIM
IPC: B32B7/027
Filed: 1993-05-14
Abstract: 2136431 9325375 PCTABS00028 An innerseal facing (10) construction is disclosed which includes three layers. An induction heatable layer (12) overlies a heat sink layer (14), which in turn overlies a bonding layer (16). The bonding layer has several strata (18, 20, 22) of material of progressively higher melting points. The construction provides an innerseal facing that may be used over a broad range of induction power levels to provide progressively stronger bonding between the innerseal facing and a container (49).
Patent CA-2136661-A1 (CA)
Title: Use of 1-{4-[4-aryl (or heteroaryl)-1-peperazinyl]-butyl}-1 -h-azole derivatives in the preparation of drugs used for treating gastric secretion disorders
Inventor: FRIGOLA-CONSTANSA JORDI
IPC: C07D249/08
Filed: 1994-11-25
Abstract: The invention relates to the use of 1-{4-[4-aryl(or heteroaryl)-1-piperazinyl]butyl}-1H-azole derivatives as well as their physiologically acceptable salts for the manufacture of medicaments intended for the treatment of disorders associated with gastric secretion.
Patent CA-2136709-A1 (CA)
Inventor: DIDILLON BLAISE
IPC: B01J38/44
Filed: 1994-11-25
Abstract: La présente invention concerne un procédé de régénération d'un catalyseur comprenant au moins un élément métallique choisi dans le groupe formé par le platine, le palladium, le ruthénium, le rhodium, l'osmium, l'iridium et le nickel, de préférence le platine, sur un support à base d'oxyde réfractaire, désactivé par le dépôt de coke. Ledit procédé de régénération est caractérisé en ce qu'il est réalisé en une seule étape. Ce procédé permet au moins de restaurer les propriétés catalytiques initiales du catalyseur.
Patent CA-2137594-A1 (CA)
Title: Welding apparatus for studs of annular cross-section
Inventor: MECKE HUBERT
IPC: B23K9/20
Filed: 1994-12-08
Abstract: For arc-welding studs of substantially annular cross-section,  a stud holder 1 is surrounded by an electromagnet coil 5, the magnetic field of which is applied to the welding gap through a magnetic flux guiding portion 6,  7 so as to generate a magnetic field component extending radially of the stud 4 within the gap. This radial field component exerts a circumferential force on the arc to move it along the annular face of the hollow stud 4 thereby securely welding the stud 4 to the workpiece 2 along its entire annular cross-section. In order to minimise coupling of the magnetic field into the conductive  workpiece  2,  the  flux  guiding  portion  has  a frusto-conical magnetic field former 7,  the generatrix of which points to the welding zone 8, with the pole surface 9 formed at the tip of the field former 7 closely surrounding the welding gap.
Patent CA-2137813-A1 (CA)
Title: Methods and compositions for inhibiting endothelial cell and fibrinogen mediated inflammation
Inventor: LANGUINO LUCIA R
IPC: C07K14/705
Filed: 1993-06-11
Abstract: The present invention contemplates therapeutic compositions containing a fibrinogen homolog capable of binding to endo-thelial cells in an RGD-independent manner that inhibits fibrinogen binding to endothelial cells. Also described are therapeutic compositions containing an ICAM-1 homolog capable of binding to fibrinogen in an RGD-independent manner that inhibits fib-rinogen binding to endothelial cells. Methods of inhibating endothelial cell and fibrinogen mediated inflammation within a pa-tient by administering a homolog of this invention are also contemplated.
Patent CA-2139382-A1 (CA)
Title: Integrated absorbent structures with density and liquid affinity gradients and methods for making the same
Inventor: YANG CHING-YUN M
IPC: A61F13/15
Filed: 1994-12-30
Abstract: There is provided by this invention at least three integrated regions, each region having distinct density and fluid affinity gradients, wherein the density and fluid affinity of the composite continuously increases from top to bottom thereby facilitating effective fluid transport and efficient utilization of storage capacity. An additional layer of SA and tissue may be provided to the absorbent product to provide an absorbent structure with dry feel and low stain. Methods of forming integrated, multi-layered absorbent composites and structures comprising at least three regions wherein each region has distinct density and fluid affinity gradients and wherein the density and fluid affinity of the composite continuously increases from top to bottom, are also provided herein.
Patent CA-2142929-A1 (CA)
Title: Cable connection for a metal-encapsulated, gas-insulated, high-voltage switching installation
Inventor: CLASSON JOHN
IPC: H02B13/075
Filed: 1995-02-20
Abstract: The cable connection is provided for a metal-encapsulated,   gas-insulated,   high-voltage   switching installation.  It has a connection enclosure  (23)  which surrounds connecting parts which are connected to the active parts of the gas-insulated, high-voltage switching installation,  and  cable  connection  encapsulation  (18) which is connected to the connection enclosure (23) and surrounds a cable termination (14) with an end bolt (15). In addition, it has an electrically conductive connecting piece which is inserted between the end bolt (15) and the connecting parts.        It is intended to create a cable connection for a metal-encapsulated, gas-insulated, high-voltage switching installation, which cable connection makes it possible to fit and remove the high-voltage cable easily and quickly and makes it possible to ground this cable reliably and in  a  manner  which  can  be  installed  easily.  This  is achieved in that the electrically conductive connecting piece is constructed such that it can easily be removed, in  that,  after  removal  of  the  connecting  piece,  a separation which  is  designed  as  an  isolating  gap  is produced between the end bolt  (15)  and the connecting parts,  and in that a grounding device  (67)  which can easily be installed is provided in this isolating gap, for reliable grounding of the end bolt (15).
Patent CA-2143111-A1 (CA)
Title: Stabilized chewable antimicrobial animal foodstuff
Inventor: MONTGOMERY ROBERT E
IPC: A61K38/44
Filed: 1993-08-27
Abstract: The invention is an animal chew which contains one or more enzymes and substrate for the purpose of generating anti-microbial compounds upon contact with an animal's saliva. The animal chew, made of rawhide, biscuit or dried animal food is provided with an oxidoreductase enzyme and substrate; such as, for example, glucose oxidase and glucose, which produces hy-drogen peroxide upon being chewed. A catalase may be provided to stabilize the system and prevent premature activation of the enzyme/substrate system. A peroxidase and halide or pseudohalide ion combination may be provided to enhance the antimicrob-ial effect of the invention.