Patent CA-3015432-A1 (CA)
Inventor: NAVARRO IKER
IPC: A61K31/00
Filed: 2017-03-20
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY  (PCT) (19) World Intellectual Property Organization                                                lll International Bureau (10) International Publication Number (43) International Publication Date                   WO 2017/158199 Al 21 September 2017 (21.09.2017) WIPO I PCT (51) International Patent Classification:                                           (81) Designated States (unless otherwise indicated, for every A61K 31/00 (2006.01)    A61P 13/12 (2006.01) kind of national protection available): AE, AG, AL, AM, A61K 31/505 (2006.01)    A61P 9/08 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, A61K 9/00 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (21) International Application Number:                                              HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, PCT/EP2017/056476                       KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, (22) International Filing Date:                                                     MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, 20 March 2017 (20.03.2017)              NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (25) Filing Language:                      English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (26) Publication Language:                 English    ZA, ZM, ZW. (30) Priority Data:                                                                 (84) Designated States (unless otherwise indicated, for every 62/310,221                     18 March 2016 (18.03.2016) US    kind of regional protection available): ARIPO (BW, GH, 16166046.9                     19 April 2016 (19.04.2016) EP    GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, 62/437,949 22 December 2016 (22.12.2016)    US                                      TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (71) Applicant: NOORIK BIOPHARMACEUTICALS AG                                        DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, [CH/CH]; Riichligweg 55, 4125 Riehen (CH).                                          LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (72) Inventors: NAVARRO, Iker; Riichligweg 55, 4125 GW, KM, ML, MR, NE, SN, TD, TG). Riehen (CH). KHANNA, Satish; Spitzackerstrasse 6, 4103 Bottmingen (CH).                            Published: (74) Agent: VAN DEN BERG, Frans; Rössligasse 30, 4132 ¨ with international search report (Art. 21(3)) Muttenz (CH). = (54) Title: AMBRISENTAN FOR USE IN THE TREATMENT OF ACUTE RENAL FAILURE (57) Abstract: Ambrisentan and formu-lations thereof for use in the treatment 1.5                                                                    and prevention of acute renal failure as sociated with renal vasoconstriction. i 0.5      0 Beatment group r*B                               ,             4 Ntt Nor-,    Samping time ::,`#) cc                       Figure 1