baber/WOPTO huggingface dataset:
Patent DE-69424552-T2 (DE)
Inventor: HARGIS E
IPC: H01S3/0941
Filed: 1994-08-22
Granted: 2001-01-18
Abstract: A monolithic diode pumped solid-state laser (11) comprising as the laser host neodymium-doped yttrium orthovanadate (Nd:YVO4) (12, 52) or neodymium-doped gadolinium orthovanadate (Nd:GdVO4) (57, 67) operating on the 4F3/2->4I9/2 ( DIFFERENCE 914 nm or  DIFFERENCE 912 nm respectively) transition, to which a suitable nonlinear optic material (16), such as potassium niobate (KNbO3) or beta barium borate (BBO), is bonded. The nonlinear crystal gives rise to intracavity frequency doubling to  DIFFERENCE 457 or  DIFFERENCE 456 nm. The microlaser is a composite cavity formed from a gain medium crystal and a nonlinear frequency doubling material which together have four spaced parallel dielectrically coated faces (14, 17, 18, 15) and which is positioned in close proximity to a diode laser pump source (13) for phase-matched harmonic generation of blue light along an axis of propagation which lies substantially perpendicular to the two faces of the composite cavity. By employing specific doping concentration-lengths products of lasant material and pumping the gain medium which has a specific crystalline orientation the desired efficient blue microlaser is achieved. Alternative embodiments combine the Nd:YVO4 and Nd:GdVO4 elements to enhance certain output characteristics of the laser.
Patent DE-69427974-T2 (DE)
Inventor: HAMERS RAYMOND
IPC: C07K16/00
Filed: 1994-04-28
Granted: 2001-12-06
Abstract: A process is provided for the production of an antibody or a fragment or functionalized fragment thereof using a transformed lower eukaryotic host containing an example DNA sequence encoding the antibody or (functionalized) fragment thereof, wherein the antibody or (functionalized) fragment thereof is derived from a heavy chain immunoglobulin of Camelidae and is devoid of light chains, and wherein the lower eukaryotic host is a mould, preferably belonging to the genera Aspergillus or Trichoderma, or a yeast, preferably belonging to the yeast genera Saccharomyces, Kluyveromyces, Hansenula, or Pichia. The heavy chain fragment can contain at least the whole variable domain. A complementary determining region (CDR) different from the CDR belonging to the natural antibody ex Camelidae can be grafted on the framework of the variable domain of the heavy chain immunoglobulin. The catalytic antibodies can be raised in Camelidae against transition state molecules. The functionalized antibody or fragment thereof can comprise a fusion protein of both a heavy chain immunoglobulin from Camelidae or a fragment thereof and another polypeptide, e.g., an enzyme, preferably an oxido-reductase. Also provided are new products obtainable by a process as described, and compositions containing a product produced by a process as described, which composition may contain a new product as provided.
Patent DE-69430761-T2 (DE)
Inventor: VARI SANDOR G DR
IPC: A61C5/02
Filed: 1994-09-28
Granted: 2003-03-06
Abstract: An endodontic apparatus for the restoration of a dead or severely decayed tooth using induced fluorescence spectroscopy. A root canal probe having an optical fiber through its center transmits excitation light into the tooth's root canal. The excitation light induces the tissue within the root canal to fluoresce. The fluorescent light is collected by the optical fiber and transmitted back to a sensor that generates electrical signals indicative of the intensity of light within predetermined wavelength bands. The electrical signals are processed to identify the tissues within the root canal. The probe may include a slightly conical metal surface having flutes for shaving and removing dentin from within the root canal. Using the fluorescent emission properties of the tissues of components of a tooth, the entrance of the root canal is located. The root canal is cleaned and shaped and the apex of the root canal located using the difference between the fluorescence spectrum of the apex and the root canal. The root canal is sealed and filled by a light cure restorative delivered into the root canal through a tube. The light cure restorative is activated by light transmitted into the root canal by an optical fiber. The light activation and polymerization of the light cure restorative can be controlled by monitoring the intensity of the restorative's fluorescence spectrum.
Patent DE-69431050-T2 (DE)
Inventor: MCCABE R TYLER
IPC: A61K31/55
Filed: 1994-04-05
Granted: 2003-03-13
Abstract: Muscarinic M2 receptor ligands are described which are suitable for the treatment of neurological disorders, and which may be administered with minimal side-effects. A method of synthesis of these compounds is also described. <IMAGE>
Patent DE-69505844-T2 (DE)
Inventor: CLUZEL GUY
IPC: B60C9/20
Filed: 1995-12-08
Granted: 1999-04-08
Abstract: PCT No. PCT/EP95/04842 Sec. 371 Date Jun. 5, 1997 Sec. 102(e) Date Jun. 5, 1997 PCT Filed Dec. 8, 1995 PCT Pub. No. WO96/20095 PCT Pub. Date Jul. 4, 1996In order to improve the endurance of the crown reinforcement (3) of a tyre, the H/S form ratio of which is at most 0.6, the latter is formed radially from the inside to the outside by a triangulation ply (31) of metal cables oriented at at least 60 DEG  and two working crown plies (32, 34) formed of inextensible metal cables oriented at angles of between 10 DEG  and 45 DEG , between which there is inserted an additional ply (33) of metallic elements oriented substantially parallel to the circumferential direction of the tire.
Patent DE-69507278-T2 (DE)
Inventor: GIRAULT MARC
IPC: G07C9/00
Filed: 1995-07-11
Granted: 1999-06-10
Abstract: PCT No. PCT/FR95/00935 Sec. 371 Date Mar. 7, 1996 Sec. 102(e) Date Mar. 7, 1996 PCT Filed Jul. 11, 1995 PCT Pub. No. WO96/02899 PCT Pub. Date Feb. 1, 1996The invention relates to systems for checking access limited to authorized time slots renewable by means of a portable storage device. The system comprises, for this purpose, an element (LE) producing electronic keys formed by a data element pertaining to a time slot and by the signature of this data element. These keys are loaded into devices such as memory cards (C). Electronic locks (L) capable of verifying the signatures are implanted in the different (physical or logical) locations, the access to which has to be guarded. Application to the checking of access to buildings or computer systems.
Patent DE-69518780-T2 (DE)
Inventor: JACOBS MERRIT NYLES
IPC: G01N35/02
Filed: 1995-04-05
Granted: 2001-02-22
Abstract: A method for verifying the effectiveness of a washing operation on a clinical dry chemistry slide element in which wash liquid is dispensed onto the surface of the slide element and then detection means are used to verify the effectiveness of the wash by making an initial detection at an on center site followed by making a second detection at a second and off-center radial position. A comparison of the two readings provides verification of the wash. In addition, rate measurements can be made at each of the read positions to measure the effectiveness of the wash and to verify sample application for immunological assays.
Patent DE-69519472-T2 (DE)
Inventor: EKSTROEM CHRISTIAN
IPC: E21B17/14
Filed: 1995-04-21
Granted: 2001-06-13
Abstract: PCT No. PCT/SE95/00434 Sec. 371 Date Mar. 31, 1997 Sec. 102(e) Date Mar. 31, 1997 PCT Filed Apr. 21, 1995 PCT Pub. No. WO95/29321 PCT Pub. Date Nov. 2, 1995A casing tube formed from plastic and a casing shoe formed from metal are provided for drilling in layers of earth or rock. The casing shoe is locked to the casing tube by threads, grooves or flanges provided on a reduced diameter portion of the casing shoe. A tube-formed extension is provided in the casing shoe for protecting the casing tube from damage during a drilling operation.
Patent DE-69525172-T2 (DE)
Inventor: VAN DE WIJDEVEN GIJSBERTUS GER
IPC: A61M5/00
Filed: 1995-10-31
Granted: 2002-09-26
Abstract: PCT No. PCT/NL95/00375 Sec. 371 Date Jun. 30, 1997 Sec. 102(e) Date Jun. 30, 1997 PCT Filed Oct. 31, 1995 PCT Pub. No. WO96/13300 PCT Pub. Date May 9, 1996The invention relates to an apparatus for injecting the body of humans or animals with a pharmaceutical preparation, wherein the preparation is arranged in a rigid carrier, wherein the apparatus comprises: a chamber into which the carrier can be transported; and a channel connecting onto the chamber for transporting the carrier into the body comprising fixation means for fixing the end of the channel relative to the skin of the body for injecting in order to prevent a movement of the channel in the direction perpendicularly of the axis of the barrel. According to one embodiment the fixation means are formed by chamfered protrusions formed on the part adapted for contact with the skin of the body and extending substantially in the direction of the axis of the channel.
Patent DE-69526515-T2 (DE)
Inventor: FLANAGAN RICHARD J
IPC: A61K51/00
Filed: 1995-10-11
Granted: 2002-11-28
Abstract: Technetium or rhenium radionuclide labelled chelate-hexapeptide complexes are useful for the selective detection or treatment of tumors with somatostatin receptors. In particular, compounds of formula:   <IMAGE>   (wherein R, R1, R3 and A are as defined herein) incorporating an N3S2 chelate may be labelled with a radionuclide. The resulting complexes are useful as radioimaging agents or as radiopharmaceuticals for the treatment of certain tumors.
Patent DE-69527405-T2 (DE)
Inventor: BOLD DR
IPC: C07D213/65
Filed: 1995-10-10
Granted: 2003-03-13
Abstract: Antiretroviral compounds (which are effective, for example, against HIV) of the formula I <CHEM>  in which R1 is an acyl radical lower-alkoxy-lower-alkanoyl whose lower alkoxy radical is unsubstituted or is substituted by halogen, phenyl, lower alkoxy or a heterocyclic radical selected from piperidinyl, pyrrolidinyl, tetrahydropyranyl, tetrahydrofuranyl, thiazolidinyl, thiazolyl, indolyl or 4H-1-benzopyranyl which is unsubstituted or substituted by oxo, hydroxyl, amino, lower alkyl, lower-alkoxycarbonyl and/or phenyl-lower-alkoxycarbonyl; lower alkanoyl which is unsubstituted or is substituted by one of the said unsubstituted or substituted heterocyclic radicals; arylcarbonyl or heterocyclylcarbonyl which are substituted by heterocyclyl or heterocyclyl-lower-alkyl; phenyl-lower-alkanoyl which is substituted by hydroxyl and lower alkyl; or arylsulfonyl; or the residue of an amino acid which is defined in accordance with the description (and which may be acylated on the amino nitrogen by one of the abovementioned acyl radicals); R2 and R3 are in each case cyclohexyl, cyclohexenyl, phenyl, naphthyl or tetrahydronaphthyl which are unsubstituted or substituted by lower alkyl, phenyl, cyanophenyl, phenyl-lower-alkyl, halogen, halo-lower-alkyl, cyano, hydroxyl, lower alkoxy, phenyl-lower-alkoxyl, pyridyl-lower-alkoxy, lower-alkoxy-lower-alkoxy, lower-alkoxycarbonyl-lower-alkoxy, carboxyl-lower-alkoxy, hydroxyl-lower-alkoxy, carbamoyl-lower-alkoxy, cyano-lower-alkoxy, and phenyl-lower-alkanesulfonyl which is unsubstituted or substituted by halogen; R4 is lower alkyl, cyclohexyl or phenyl; and R5 is lower alkyl; and n is 1 or 2, or salts thereof, are novel.
Patent DE-69533004-T2 (DE)
Inventor: COOPER ROBIN DAVID GREY
IPC: A61P31/00
Filed: 1995-01-25
Granted: 2005-04-07
Abstract: A new glycopeptide molecule is inserted into the antibiotic group and both components are mixed with a standard pharmaceutical carrier.
Patent DE-69601828-T2 (DE)
Inventor: VANDI TIZIANO
IPC: G04G15/00
Filed: 1996-05-10
Granted: 1999-09-09
Abstract: Multifunctional timer comprising: a control circuit (17) actuated by a push-button (13); a circuit (19), flip-flop type; a timing circuit (25) equipped with trimmer (27); a circuit (29) against initial startup; a load switching relay (31); and a power supplying circuit (15) for all components of the multifunctional timer. This multifunctional timer can perform, upon a choice, one among the functions of: a) timed pulse relay; b) resettable timer; c) pulse relay; and d) relay lock on the ON position. <IMAGE>
Patent DE-69604825-T2 (DE)
Inventor: DEN HARTOG HUIBERT
IPC: B21B1/24
Filed: 1996-12-20
Granted: 2000-05-25
Abstract: Continuous casting machine for the casting of a thin slab with a thickness of less than 150 mm comprising a vacuum tundish having a first atmospheric chamber (7) and a second low pressure or vacuum chamber (1) hydraulically connected to the first chamber and purging means (11) for introducing a purging gas into the liquid steel after it has entered the first chamber but before it entered the second chamber.
Patent DE-69614891-T2 (DE)
Inventor: KUCKART STEPHANIE
IPC: D21F7/10
Filed: 1996-11-13
Granted: 2002-04-18
Abstract: A papermakers fabric has concentric double pin seam loops on each end for enabling it to be seamed to form an endless form for use on a papermaking machine. A seaming method for making double seaming loops is also provided.
Patent DE-69617228-T2 (DE)
Inventor: BOVENBERG ARY
IPC: C12R1/365
Filed: 1996-06-03
Granted: 2002-06-27
Abstract: PCT No. PCT/EP96/02434 Sec. 371 Date Feb. 18, 1998 Sec. 102(e) Date Feb. 18, 1998 PCT Filed Jun. 3, 1996 PCT Pub. No. WO96/38580 PCT Pub. Date Dec. 5, 1996A process is taught for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G, using a Penicillium chrysogenum transformant strain expressing expandase.
Patent DE-69617788-T2 (DE)
Inventor: KATO KANEYOSHI
IPC: C07D215/20
Filed: 1996-04-10
Granted: 2002-06-20
Abstract: The present invention relates to a compound of the formula: <CHEM> wherein Ar represents an optionally substituted aromatic group; Q represents a divalent aliphatic hydrocarbon group; R<1> represents hydrogen, cyano, an optionally substituted hydrocarbon group, a group of the formula: <CHEM> wherein R<3> and R<4> independently represent hydrogen, acyl or an optionally substituted hydrocarbon group, or R<3> and R<4> jointly form a ring, or acyl; R<2> represents acyl; ......... represents a single bond or a double bond; m represents 1 or 2 or a salt, a process of producing-thereof and an anti-neurodegenerative composition.
Patent DE-69619084-T2 (DE)
Inventor: POZZOBON ALESSANDRO
IPC: A43B5/16
Filed: 1996-12-10
Granted: 2002-11-14
Abstract: A method for manufacturing a shoe, particularly for skates, entails the positioning of a soft innerboot (2) on an adapted last and the subsequent dry assembly of a rigid shell (11) made of plastics to the innerboot. An overlap injection-molding or pouring of thermoplastic or thermosetting material is then performed on at least part of the edge (21) of the shell so as to affect the innerboot and the frame, in order to achieve a skate that simultaneously provides comfort for the user's foot and optimum transmission of forces at the underlying supporting frame for the wheels that are associated below the shell. <IMAGE>
Patent DE-69627438-T2 (DE)
Inventor: BAYART DOMINIQUE
IPC: H03G3/30
Filed: 1996-09-04
Granted: 2004-02-12
Abstract: The method involves use of an optical equalisation module (4) including an attenuator (5) adjusted by a monitor (6) which comprises a tunable photo-refractive filter (19) and a photodetector (21) with management logic (20). The attenuator has a convertor (17) which controls tunable photo-refractive filters (16a-16n) for different channels. The attenuator is followed by an Er-doped fibre amplifier (3) with multiplexers (10,11) of pumping waves from laser diodes (8,9) supplied with controlled currents from a regulator (12) in response to the level measured by a photodiode (13).
Patent DE-69630002-T2 (DE)
Inventor: LASHINSKI ROBERT
IPC: A61F2/958
Filed: 1996-12-05
Granted: 2004-06-09
Abstract: The disclosure relates to a delivery, deployment and retrieval device for a stent (28) made from a phase-change material including a balloon catheter (22) modified to allow the stent to be secured on the outside of the balloon (27) without the need for a sheath. A temperature-controlled fluid to effect a phase change to expand the stent is injected through an inflation lumen (25) to maintain the selected temperature and to inflate the balloon. The balloon maintains intimate physical and thermal contact with the stent during deployment. One or more exit apertures (29) are provided for the fluid to escape from the inflation lumen and enhance the phase change by bathing the stent with the fluid. <IMAGE>
Patent DE-69635584-T2 (DE)
Inventor: BURTON J
IPC: C12P21/06
Filed: 1996-10-24
Granted: 2006-09-21
Abstract: Stable compositions containing biotinylated molecules, such as enzymes, are provided. The compositions include a biotinylated biomolecule, a biomolecule protectant, a buffer, a bulking agent selected from one or more water soluble, nonionic polymers and preferably a terminal sterilization protectant. The compositions can be utilized either as aqueous solutions or preferably in dried form, e.g., as a lyophilized, powder cake. They have applicability in any case where avidin/biotin technology is used and are particularly important as compositions containing a thrombin-like enzyme, e.g., for preparation of a fibrin monomer and fibrin monomer-based fibrin sealants.
Patent DE-69700834-T2 (DE)
Inventor: LEWIS DAVID
IPC: A61J3/10
Filed: 1997-01-22
Granted: 2000-06-21
Abstract: Compression forces (F) in a rotary tablet compressing machine (40) are monitored and controlled to provide enhanced accuracy in determining peak compression value and continuous validation of a compression waveform. The compression waveform is repetitively sampled under computer control at a sampling frequency that is many times the frequency of the compression events. The samples are stored in a computer memory (26) until at least one complete compression event is recorded. Identification of beginning and ending samples of an individual tablet compression event are obtained from the waveform itself by locating minimum amplitude samples, or by use of a separate signal that is derived from a transducer which is responsive to the angular position of a rotating turret. Stored samples representing the compression waveform as time and amplitude data are passed to a processor (23) that statistically fits the data to an equation form which represents the ideal shape of a compression event. If the quality of the data fit falls below a preset value, the tablet associated with that coefficient is subsequently rejected by a mechanism that is activated by the computer (26), which records the event as a waveform error. A counter (25), having a user selectable maximum threshold, is incremented each time a tablet is rejected from the same punch pair as a result of a waveform error. If the maximum count threshold is reached, then the tablet compressing machine (40) is stopped by the computer (26) and a message identifying the faulty punch pair is displayed.
Patent DE-69717142-T2 (DE)
Inventor: PEDUTO NICOLANGELO
IPC: B32B27/30
Filed: 1997-12-09
Granted: 2003-04-24
Abstract: The invention concerns a plastic-based multilayer structure, in particular for making tubes or conduits for transporting liquid fluids such as alcohol, liquid fuels derived from petrol, fuels containing oxygen compounds such as, for instance alcohol. More particularly it concerns a multilayer structure comprising an external layer (A) formed from a polyamide based composition with and an internal adjacent layer (B) formed from a polyfluorovinylidene based composition.
Patent DE-69720274-T2 (DE)
Inventor: POLIAC O
IPC: A61B5/022
Filed: 1997-05-28
Granted: 2004-02-05
Abstract: A method for identifying an onset of a first heart beat includes sensing blood pressure over time to produce a plurality of blood pressure samples, each sample having a corresponding blood pressure amplitude in time, identifying a post onset point in time following an onset of the first heart beat and preceding an onset of a second heart beat, and identifying an onset of the heart beat based upon the blood pressure samples and the post onset point.
Patent DE-69725460-T2 (DE)
Inventor: EBRINGER ALAN
IPC: G01N33/68
Filed: 1997-09-29
Granted: 2004-06-09
Abstract: A diagnostic test is provided for spongiform encephalopathy and other demyelinating conditions in mammals which comprises assaying antibodies present in the mammal which bind to an antigenic peptide which exhibits molecular mimicry of a mammalian myelin peptide, e.g. one having the sequence FSWGAEGQK. This test is useful for detecting BSE in cattle by assaying sera collected from the cattle for antibodies to a species of Acinetobacter, Agrobacterium or Ruminococcus, or a peptide having a sequence present in the species which mimics a peptide of bovine myelin and identifying animals having a level of antibodies at least about two standard deviations above that of healthy control animals.
Patent DE-69729066-T2 (DE)
Inventor: RITCHART A
IPC: A61B18/14
Filed: 1997-08-27
Granted: 2005-05-12
Abstract: This invention provides an inventive tissue sampling probe which offers many advantages over probes available in the prior art. Unexpectedly superior results are obtained in connection with the retrieval of intact tissue specimens, because of a unique combination of cutting features, including, for example, the employment of an electrosurgical cutting element and a vacuum assist in one preferred embodiment. A particularly important feature of the invention is the ability to manipulate the electrosurgical cutting element to cleanly sever the distal end of the tissue specimen. In certain embodiments, this is accomplished without any cutting impact on surrounding tissue. The versatility of the invention permits its use in many applications, including, for example, breast biopsies, laparoscopic surgery, and lymphadenectomy procedures.
Patent DE-69731103-T2 (DE)
Inventor: HOLTUND JOSTEIN
IPC: G01N33/72
Filed: 1997-11-03
Granted: 2005-11-17
Abstract: The present invention provides a process for the extraction of proteins from gastrointestinal tract samples taken from humans or other mammals wherein the sample is mixed with an excess amount of aqueous extraction medium comprising at least one dissociating, disaggregating and/or chelating agent, homogenised in a closed vessel, the solid and liquid materials of the dispersion are separated from each other and the clear liquid extract is recovered.
Patent DE-69734225-T2 (DE)
Inventor: COUSTON LAURENT
IPC: G01N21/43
Filed: 1997-07-30
Granted: 2006-06-22
Abstract: The sensor is used for analysis of a fluid (24) and includes: a transmitter/receiver (22) designed to emit a light beam capable of interacting with the fluid and to receive the light beam after its interaction with the fluid; a tubular light guide (26) which is designed to be immersed in the fluid, and whose first end is placed with respect the transmitter/receiver(22) and whose second end is designed to reflect the light which is propagated by the guide; and means (32) which maintain the guide at a distance from the transmitter/receiver. This distance permits the formation of the evanescent wave in the fluid when the light is propagated in the guide. The unit (22) includes: central fibre optics (34) which is designed to emit light, the end of this fibre is situated with respect to the tubular guide and the latter is co-axial; and the peripheral optical fibres (36), which surround the central fibre (34), designed to receive the light leaving the first end of the guide.
Patent DE-69812114-T2 (DE)
Inventor: HAEFLIGER HANSPETER
IPC: A23P10/22
Filed: 1998-12-10
Granted: 2003-12-24
Abstract: A granular baking improver product, which has a mean particle diameter of from 300 to 500  mu m, less than 1% by volume of the particles having a diameter smaller than 50  mu m, and a process for the production of such a granular baking improver product, which consists of preparing a premix of powdered constituents and forming the premix into granules or agglomerates by continuously dispersing liquid malt extract and liquid emulsifier into a flow of the premix.