baber/WOPTO huggingface dataset:
Patent EP-0876152-B1 (EP)
Inventor: THOMAS GRIFFITH R
IPC: A61P7/00
Filed: 1997-01-13
Granted: 2002-04-17
Abstract: The present invention is directed to the surprising and unexpected finding that biologically active thrombopoietin materials can be administered with substantial therapeutic effect at dosage rates commensurate with previously reported administration of such materials, but in a single or low-multiple daily administration. Thus, the predicate of the present invention relates to the reversal of thrombocytopenia by administering to a patient having or in need of such treatment a single or low-multiple daily dose of a therapeutically effective amount of a thrombopoietin. The preferable dose of the active material ranges from about 1 to about 10  mu g/kg body weight.
Patent EP-0941352-B1 (EP)
Inventor: JOBLING STEPHEN ALAN
IPC: C12N9/10
Filed: 1997-11-04
Granted: 2006-05-31
Abstract: This invention provides isolated cassava nucleic acids encoding starch branching enzyme II (SBEII); constructs, vectors and host cells comprising the nucleic acids; and methods of using the nucleic acids to alter gene expression in cassava to obtain starch with altered properties.
Patent EP-0929554-B1 (EP)
Inventor: HAWORTH KAREN ELIZABETH
IPC: A61P19/02
Filed: 1997-09-18
Granted: 2006-03-15
Abstract: PCT No. PCT/GB97/02532 Sec. 371 Date Mar. 23, 1999 Sec. 102(e) Date Mar. 23, 1999 PCT Filed Sep. 18, 1997 PCT Pub. No. WO98/13369 PCT Pub. Date Apr. 2, 1998The present invention relates to certain spiro-azacyclic derivatives which are tachykinin antagonists and are useful, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
Patent EP-0898482-B1 (EP)
Inventor: SAUER JUDE S
IPC: A61M16/04
Filed: 1997-04-16
Granted: 2004-11-24
Abstract: L'invention concerne un dispositif chirurgical (10) servant à manipuler les tissus biologiques et comprenant une aiguille creuse (41), un bulbe (24) raccordé à l'aiguille et permettant d'aspirer l'air par une extrémité de l'aiguille, un fil de guidage flexible (31) s'étendant dans l'aiguille, un raccord (29) monté à une extrémité du fil de guidage et permettant de faire aller et venir le fil de guidage, de la même main que celle qui tient l'appareil, d'une position rétractée, dans l'aiguille, à une position déployée dans laquelle une bonne longueur du fil de guidage s'étend et dépasse une extrémité de l'aiguille, un dilatateur extensible (30) fixé à l'embout de dilatation (68) et servant à dilater une paroi trachéale lorsque le dilatateur est gonflé, et une canule de trachéotomie (28) montée amovible par rapport au dilatateur pour pouvoir être placée dans un lumen de la trachée.
Patent EP-0959771-B1 (EP)
Inventor: MORASSE LOUIS
IPC: G03B42/04
Filed: 1997-07-08
Granted: 2003-10-08
Abstract: The invention discloses a mobile X-ray device comprising a frame (1) with wheels (2, 3), an X-ray generator and a container (7) for a plurality of cassettes each containing a film printable by X-ray and to be developed in a processing chamber. The cassette container (7) is detachable from the mobile X-ray device for transporting the said cassettes to the processing chamber, the container (7) comprising rolling means (18) and gripping means (20) for an operator.
Patent EP-0983080-B1 (EP)
Title: Synthetische, statistische thymuspeptid-kombination und deren verwendung als immunologisch und/oder endokrinologisch wirkendes praparat
Inventor: KLETT-LOCH LORE MARIA
IPC: A61K38/00
Filed: 1997-05-26
Granted: 2004-09-29
Abstract: Immunologisch und/oder endokrinologisch wirkendes Präparat enthaltend als Wirkstoff kurzkettige Peptide mit einem für Thymusgewebe charakteristich gewichteten Mengenverhältnis und Muster an Aminosäuren.
Patent EP-0870955-B1 (EP)
Inventor: MICHAEL JOERG
IPC: F16H63/42
Filed: 1998-03-12
Granted: 2002-09-11
Abstract: The mechanism has a self-resetting selector lever. The selected operating position, and other positions which can be selected from it, are always indicated, and there are more operating positions than there are directions in which the lever can be deflected. The actually-selected operating position and the further ones which can be selected are always shown on the same side. For selection of each particular operating position the lever must always be deflected in the same direction. The direction in which the lever must be deflected to give the operating position already selected can be optically displayed in a different manner to those in which deflection must take place to give the positions not selected.
Patent EP-0910961-B1 (EP)
Inventor: DE MEUTER PASCALE ADOLPHINE EM
IPC: A23L1/00
Filed: 1998-10-22
Granted: 2006-09-20
Abstract: The present invention relates to protein based films, coatings or foils. The films coatings or foils of the present invention are obtained after extrusion and contain hydrolysed protein or hydrolysed protein mixtures. The present invention also relates to a process for the formation of protein based films, coatings or foils. The films are usable as packaging material in general, particular applications relate to the packaging of food or feed.
Patent EP-0884745-B1 (EP)
Inventor: PERRET MICHEL
IPC: H01H33/16
Filed: 1998-06-08
Granted: 2004-03-17
Abstract: The resistive closing mechanism has a semi-mobile block which moves along an axial direction and pushes a set of two arc contacts (15,16) into place. A set of two further arc contacts are pushed forward in sequence, ending with these contacts (8,11) connecting permanent contacts (9,12). There is a venting tube (13) is in the first and second contact area.
Patent EP-0955052-B1 (EP)
Inventor: BAE ILL-JU
IPC: A61P35/00
Filed: 1998-07-17
Granted: 2004-10-06
Abstract: This invention is about the identification of the HD-2, a natural chemical substance that was separated and purified from a natural product, Sinsuk, as arsenic hexoxide (As4O6) and about its therapeutic efficacy as an anti-cancer drug and pharmaceutical compositionn, Arsenic hexoxide (As4O6), a natural chemical substance obtained from Sinsuk after eliminating the toxic property, has a potent anti-cancer efficacy by its direct cytotoxicity on tumor cells and suppresses the formation of new blood vessels of tumor masses, which results in complete cure of malignant cancers.
Patent EP-0875293-B1 (EP)
Inventor: DEPAULIS ROBERT
IPC: B01L99/00
Filed: 1998-04-28
Granted: 2003-06-18
Abstract: The transfer unit, designed to pick up a calibrated droplet of blood from a transfusion pouch sample segment for matching, consists of a tube (1) which is open at one end (3) and closed at the other (2). The closed end contains a cannula (4) with a pointed inner end (5). The tubular segment (9) containing the sample for testing is inserted into the open end of the tube after folding it in two, so that one half of it is pierced by the cannula. The folded segment is guided towards the cannula by the inner surface of the tube, which has a cross-section in the form of two isosceles trapezia joined by their larger bases and having their smaller bases rounded.
Patent EP-0961680-B1 (EP)
Inventor: WROBBEL WERNER
IPC: B29C49/48
Filed: 1998-01-07
Granted: 2000-11-22
Abstract: Ce procédé de soufflage par extrusion permet de fabriquer des pièces moulées en plastique avec des contours à arêtes vives fortement marquées et/ou des contre-dépouilles dans la zone de passages. Le tuyau en plastique (5) introduit dans l'outil de soufflage (3) est premièrement élargi par la pression pneumatique interne, moulé et retenu sur les surfaces planes ou légèrement en relief de l'outil de soufflage (3a, 3b). Les contours à arêtes vives marquées, par contre, sont façonnés au moyen d'une pression mécanique appliquée sur le côté extérieur du tuyau en plastique (5) par un outil de façonnage (2). Le dispositif de mise en oeuvre du procédé comprend un outil de soufflage (3) dont la paroi comprend des coulisses de façonnage (2) en une ou plusieurs pièces mobiles à l'intérieur de l'outil de soufflage et dont les parties coulissantes (2a, 2b, 2c) peuvent être entraînées indépendamment les unes des autres ou en synchronie.
Patent EP-0917771-B1 (EP)
Inventor: SIPILAE KARI
IPC: H04B7/26
Filed: 1998-04-09
Granted: 2004-07-28
Abstract: The invention relates to a method of determining the average effect of radio wave multipath fading in a desired area in a radio system. The desired area of a coverage area of a base station in the system is described by a digital map. The average effect of multipath fading of a transmitter output is determined in different sub-areas of the desired area. In order to reduce the computation amount signal fading parameters are determined at some point of each sub-area by a ray tracing method and the average effect of signal multipath fading in the sub-area is calculated using said parameters.
Patent EP-0977486-B1 (EP)
Title: Humane crustacean processor
Inventor: BUCKHAVEN SIMON
IPC: A22B3/06
Filed: 1998-04-27
Granted: 2003-09-17
Abstract: PCT No. PCT/GB98/01219 Sec. 371 Date Dec. 30, 1999 Sec. 102(e) Date Dec. 30, 1999 PCT Filed Apr. 27, 1998 PCT Pub. No. WO98/48635 PCT Pub. Date Nov. 5, 1998An apparatus for applying an electric current to a crustacean comprising: (i) an electrically insulated tank adapted to contain the crustacean; (ii) two electrodes arranged such that the crustacean can be placed between the electrodes; and (iii) means for creating an electrical potential across the electrodes such that in use current flows between the electrodes and through the crustacean such that the crustacean is anaesthetised or killed.
Patent EP-0971084-B1 (EP)
Inventor: WASSERBAUER RALF
IPC: E04C5/20
Filed: 1999-07-03
Granted: 2004-06-23
Abstract: The abutment has a cylindrical jacket (1) which has two end surfaces (2,4) from which a serrated support surface is formed. An intermediate base is also formed that extends from one side of the jacket to another. An opening is provided in the base of the abutment to enable it to be attached to the formwork with at least one other opening provided in the jacket.
Patent EP-0982194-B1 (EP)
Inventor: RECH BERND DR-ING
IPC: B60R16/02
Filed: 1999-07-21
Granted: 2004-10-06
Abstract: The control method has the auxiliary electrical loads (1,2) divided into different priority groups and further divided via defined control algorithms, with operation of the loads by evaluation of the operating requirements. The electrical loads within at least one group can be operated via a pulse width modulation control, with time offset operation of at least 2 loads, so that one load is switched on during the intervals when the other load is switched off.
Patent EP-0979641-B1 (EP)
Inventor: ELLIS JONATHAN STUART
IPC: A61G1/013
Filed: 1999-05-12
Granted: 2007-01-24
Abstract: A trolley 10 can be moved between a raised position and a lowered position. The trolley is usually in the lowered position when it is put into an ambulance. A magnet 252 is secured to one connecting leg of the trolley and a counter 258 is connected to the top frame 16 of the trolley. When the trolley is moved to a lower position the magnet 252 comes in close proximity to the counter 258 and a count is recorded. The recorded count gives an indication of the number of times that the trolley has been raised and lowered. <IMAGE>
Patent EP-0940386-B1 (EP)
Inventor: PEGLION JEAN-LOUIS
IPC: C07D345/00
Filed: 1999-03-03
Granted: 2002-05-22
Abstract: Benzocyclobutane derivatives (I) are new. Benzocyclobutane derivatives of formula (I) and their isomers and acid-addition salts are new: Z1-Z4 = H, halogen, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, (3-8C)cycloalkyl(1-6C)alkyl, OH, 1-6C alkoxy, benzyloxy 2-6C alkenyloxy, 2-6C alkynyloxy, CN, CF3, OCF3, NO2, OSO2CF3, OSO2Me, NHCOMe, NHCOCF3, NHSO2Me, NR1R2 or CONR1R2; R1, R2 = H, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, aryl(1-6C)alkyl or (3-8C)cycloalkyl(1-6C)alkyl; X = O, SOp, (CH2)n or CH2YCH2; p = 0-2; n = 1-4; Y = O, Se, SOp, NR1 or CR1R2; A = (CH2)mQ; Q = NR1R2, 4,5-dihydro-2-oxazolylamino or 4,5-dihydro-1H-imidazol-2-ylamino; m = 1-6. An Independent claim is also included for the preparation of (I).
Patent EP-1010413-B1 (EP)
Inventor: SIMONNET JEAN-THIERRY
IPC: A61K8/60
Filed: 1999-11-16
Granted: 2002-11-20
Abstract: A nanoemulsion comprising a dispersed lipid phase in an aqueous phase with the lipid globules having an average size of less than 100 nm contains: (1) a surfactant (solid at up to 45 degrees C) such as esters or ethers of fatty acid and sugar; and (2) at least one oil with a molecular weight of more than 400, at a lipid phase/surfactant weight ratio of 2-10. Independent claims are also included for: (1) a topical composition comprising the above described composition;   (2) an ophthalmic support comprising the above described composition;   (3) a pharmaceutical composition comprising the above described composition; (4) a cosmetic method for the care and/or hydration of the skin, mucosa and/or scalp by applying the above described composition; and (5) the preparation of the composition by mixing an aqueous phase and a lipid phase at 10-80 degrees C and homogenizing the mixture at 6 x 10<7>-18 x 10<7> Pa.
Patent EP-1054828-B1 (EP)
Inventor: FREUDELSPERGER KARL
IPC: B65G59/10
Filed: 1999-02-12
Granted: 2002-09-11
Abstract: An arrangement (1, 1') for automatically unstacking containers (6, 6') nested in each other in lying posture, by depositing them on a support, e.g. a conveyor (3a), with the container opening (6a) facing upwards, the arrangement comprising a gripping device (5) for gripping and moving out the respective first container (6) of a lying container stack (2, 2'), the gripping device (5, 5') being arranged on holding elements (8a, 8b) movable in stacking direction, and further comprising a clamping device (4) for holding back the lying container stack (2, 2'), with the foremost container (6) being left free, wherein the gripping device (5) is provided with lateral pressure-medium cylinders (5a; 46) which have horizontal axes on the same level and which are connected with the holding elements (8a, 8b) extending thereabove.
Patent EP-1056987-B1 (EP)
Inventor: HARTRUMPF MATTHIAS
IPC: G01S7/481
Filed: 1999-02-11
Granted: 2005-04-27
Abstract: The invention relates to a laser scanner measurement system, comprising a transmission unit consisting of a laser, beam deflection unit and transmitting optical system, and a receiving part with a photodetector which is arranged in the focal plane of the optical system destined for the receiving beam path. The invention is characterized in that the scanner unit and receiving unit are arranged on the same side in relation to the object and the surface normal of the receiving optical system is parallel to the direction of radiation of the scanner unit, i.e. that the scanner and receiver beam path in the outer area at all times have the same optical axis or that the axes are displaced parallel to each other and perpendicular to the direction ofmovement of the laser beam.
Patent EP-1066478-B1 (EP)
Inventor: THOMAS PAUL
IPC: F16D65/14
Filed: 1999-03-23
Granted: 2004-05-26
Abstract: An actuator (13) device for a disc brake (4) is provided comprising a rotary actuator (13) operable, via a force transmission device (17, 18), to move a friction element (2) of the brake, in use, into engagement with a rotary brake disc (4), and a thrust member (17A, 18A) arranged to transmit force from the actuator (13) to the force transmission device (17, 18), the actuator (13) being arranged to engage the thrust member (17A, 18A) in a manner such as to prevent rotation of the latter.
Patent EP-1070049-B1 (EP)
Inventor: SOLL RICHARD M
IPC: A61K31/5375
Filed: 1999-04-05
Granted: 2004-06-30
Abstract: The present invention is directed to aminoguanidine and alkoxyguanidine compounds, including compounds of Formula I:wherein X is O or NH, L is -O- or -SO2-, and R1-R4, R9-R19, Ra, Rb, Rc, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit proteolytic enzymes such as thrombin. Also described are methods for preparing the compounds of Formula I. Certain of the compounds exhibit antithrombotic activity via direct, selective inhibition of thrombin, or are intermediates useful for forming compounds having antithrombotic activity. The invention includes a composition for inhibiting loss of blood platelets, inhibiting formation of blood platelet aggregates, inhibiting formation of fibrin, inhibiting thrombus formation, and inhibiting embolus formation in a mammal. Other uses of compounds of the invention are as anticoagulants either embedded in or physically linked to materials used in the manufacture of devices used in blood collection, blood circulation, and blood storage.
Patent EP-1066303-B1 (EP)
Title: Compose de metaux de transition contenant des groupes cationiques, utilise comme composant de catalyseur pour la polymerisation d'olefines
Inventor: GOERES MARKUS
IPC: C07F17/00
Filed: 1999-03-17
Granted: 2003-09-10
Abstract: L'invention concerne des métallocènes spécialement substitués et leur utilisation lors de la polymérisation d'oléfines. Les composés selon l'invention contiennent un groupe cationique comme substituant et font partie intégrante d'un système catalyseur pour la polymérisation d'oléfines.
Patent EP-1077979-B1 (EP)
Inventor: FEY PETER
IPC: C07D471/04
Filed: 1999-04-28
Granted: 2005-07-06
Abstract: L'invention concerne un procédé de préparation de (S,S)-8-benzyle-2,8-diazabicyclo[4.3.0]nonane.
Patent EP-1115590-B1 (EP)
Inventor: PIECH FERDINAND
IPC: B60K17/344
Filed: 1999-04-22
Granted: 2002-07-31
Abstract: The invention aims at providing a compact mounting arrangement for an automobile drive unit consisting of a combustion engine and a transmission. According to the invention, the crankshaft of the combustion engine and an auxiliary shaft driven by said crankshaft extend in the longitudinal direction of the vehicle, the cylinders of the combustion engine are subdivided into at least two rows forming an angle in relation to each other, wherein one of said cylinder rows is disposed in a horizontal or substantially horizontal manner.
Patent EP-1104301-B1 (EP)
Inventor: CEDAR EVE NAOMI
IPC: A61P25/00
Filed: 1999-07-15
Granted: 2009-10-07
Abstract: The use of [R-(Z)]-alpha-(methoxyimino)-alpha-(1-azabicyclo[2.2.2]oct-3-yl)acetonitrile or a pharmaceutically acceptable salt thereof for the treatment of psychosis or other neuropsychiatric symptoms.
Patent EP-1105495-B1 (EP)
Inventor: BUONAMASSA DANIELA TORNESE
IPC: C12N15/37
Filed: 1999-08-13
Granted: 2005-03-16
Abstract: Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production conformational antibodies against both L1 proteins upon administration to mice.
Patent EP-1127042-B1 (EP)
Inventor: LE BERRE CAROLE
IPC: C07C51/12
Filed: 1999-10-29
Granted: 2003-07-23
Abstract: The invention relates to a process for the preparation of acetic acid and/or methyl acetate in the liquid phase by the carbonylation of methanol and/or the isomerization of methyl formate in the presence of water, a solvent, a homogeneous catalyst system comprising iridium and a halogen-containing promoter, and carbon monoxide, wherein said catalyst system also comprises platinum.
Patent EP-1131072-B1 (EP)
Inventor: HELLER RUDOLF
IPC: A61K9/28
Filed: 1999-11-20
Granted: 2003-04-23
Abstract: La présente invention concerne une spécialité pharmaceutique combinée destinée au traitement de troubles cardiaques et cardio-vasculaires tels que l'hypertension, l'angine de poitrine, l'insuffisance cardiaque et les maladies associées. Cette spécialité associe deux principes actifs, en l'occurrence le carvedilol, ou l'un de ses sels pharmaceutiquement admis, et l'hydrochlorothiazide, ou l'un de ses sels pharmaceutiquement admis, auxquels s'ajoutent des additifs communément admis en pharmacie.
Patent EP-1141556-B1 (EP)
Inventor: HEMMERVALL JAN-OLOF
IPC: F16L3/10
Filed: 1999-11-30
Granted: 2004-06-09
Abstract: A clamping device for mounting on a profile member (P) comprises two clamping jaws (10, 11) which are intended to be placed in front of each other at mutually opposite sides of the profile member (P) and each of which comprises an inner portion (12, 13) and two end portions (14, 15), projecting in mutually opposite directions from the inner portion and formed integrally with the inner portion, said end portions being provided with through holes (16, 17) for clamping bolts (18) by means of which the two clamping jaws (10, 11) can be brought to bear under pressure against the profile member (P) with contact surfaces (19, 20, 21) thereof, formed by the inner portions (12, 13) of the clamping jaws. The inner portion (12) of at least one (10) of the two clamping jaws (10, 11) is provided with profiled contact surfaces (19, 20) of mutually different shapes at mutually opposite sides of said portion (12).
Patent EP-1140240-B1 (EP)
Inventor: RADICE MARCO
IPC: C12N5/08
Filed: 1999-12-21
Granted: 2005-03-02
Abstract: Disclosed is an injectable, biocompatible and biodegradable composition, comprising at least one hyaluronic acid benzyl ester or auto-cross-linked derivative, in combination with at least one mammalian cell and/or at least one pharmacologically or biologically active substance and/or micro-particles such as fibres, granules, microspheres or sponge fragments of a hyaluronic acid derivative.
Patent EP-1140802-B1 (EP)
Inventor: PRIEPKE HENNING
IPC: C07D277/24
Filed: 1999-12-13
Granted: 2004-03-17
Abstract: Compounds that prolong thrombin time. Exemplary are:(a) rac-4-{3-[5-ethoxycarbonylmethyl-2-methyl-4-(2-methyl-pyrrolidinocarbonyl)-phenyl]-propargylamino}benzamidine,(b) rac-4-{3-[2,5-dimethyl-4-(2-methyl-pyrrolidinocarbonyl)-phenyl]-propargylamino}benzamidine, and(c) 4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine.
Patent EP-1124773-B1 (EP)
Inventor: SLAVID IRVING O
IPC: C04B41/45
Filed: 1999-10-28
Granted: 2005-12-14
Abstract: Embodiments provide methods for the protection and consolidation of calcareous materials. An exemplary method includes providing an aqueous solution of a hydroxycarboxylic acid, adjusting the pH of the aqueous solution by adding an alkaline agent, and applying the pH-adjusted aqueous solution to a calcareous mineral to form a conversion layer on the mineral. The calcareous mineral may, for example, be carbonate rock, particularly limestone and marble, or may be part of masonry material, aggregates, or fillers. Adherent conversion layers are readily formed at ambient temperatures and, therefore, methods provided are suitable for field application. Conversion layers so formed are provided as further embodiments.
Patent EP-1131527-B1 (EP)
Inventor: LAFOND LUC
IPC: E06B3/673
Filed: 1999-11-04
Granted: 2003-03-26
Abstract: An apparatus and method to seal a spacer between a pair of substrates within an IG assembly having a pair of spaced apart substrates and a bondable spacer therebetween, having support means for supporting an IG assembly to be treated and zonal energy applying means to locally apply energy to selected zones of the IG assembly where said spacer is located without providing direct energy to the balance of the IG assembly.
Patent IE-87303-B1 (IE)
Title: N2 generator with argon co-production
Inventor: LOIC JOLY
IPC: F25J3/04
Filed: 2019-03-19
Abstract: An apparatus 100 for producing product nitrogen gas and product argon, comprising: a first rectiﬁcation column 2 into which raw air is introduced; a second rectiﬁcation column 5 from which product nitrogen gas is drawn; a third rectiﬁcation column 6 from which product argon gas is drawn; and a first condenser 3 conﬁgured to perform heat exchange between a gas accumulated in a column top portion of the ﬁrst rectiﬁcation column 2, and a liquid accumulated in a column bottom portion of the second rectification column 5, wherein an intermediate portion gas containing nitrogen is drawn from an intermediate portion of the second rectiﬁcation column 5 and merged with a condenser gas drawn from the ﬁrst condenser 3. The merged gases are expanded and cooled by means of an expansion turbine 8 whereby the cold thereof is utilized.