Patent SG-11201909323Y-A (SG)
Title: Apparatus and method for picking biological sample
Inventor: CHRISTEY PETER
IPC: G01N35/10
Filed: 2017-10-19
Abstract: 1 N O 01 O 01 1-1 00 O O 1-1 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 18 October 2018 (18.10.2018) WIPO I PCT ill 1111u°11111VIIIVIIIVIIIolo VIII im Imo oimIE (10) International Publication Number WO 2018/190907 Al (51) International Patent Classification: G01N 35/04 (2006.01) GO1N 35/10 (2006.01) (21) International Application Number: PCT/US2017/057482 (22) International Filing Date: 19 October 2017 (19.10.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/484,395 12 April 2017 (12.04.2017) US (63) Related by continuation (CON) or continuation-in-part (CIP) to earlier application: US 15135377 (CIP) Filed on 21 April 2016 (21.04.2016) (71) Applicant: GENERAL AUTOMATION LAB TECH- NOLOGIES, INC. [US/US]; 953 Indiana Street, Suite 372, San Francisco, California 94107 (US). (72) Inventors: CHRISTEY, Peter; 3828 26th Street, San Francisco, California 94131 (US). HALLOCK, Alexan- der; 105 Camellia Avenue, Redwood City, California 94061 (US). (74) Agent: SUN-HOFFMAN, Lin; P.O. Box 52048, Palo Alto, California 94303 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (54) Title: APPARATUS AND METHOD FOR PICKING BIOLOGICAL SAMPLE 125 100' FIG. 2 (57) : A picking instrument for picking biological samples, such as microbial samples, includes a picking pin having a distal tip and three degrees-of-freedom and configured to move in x, y, and z directions. The picking instrument also includes a loading platform comprising a first area and a second area, the first area configured to accommodate and secure a microfabricated chip including a plurality of microwells. The picking pin is programmatically controlled to pick a sample contained in one or more selected microwells of the microfabricated chip and then transfer the sample to a predetermined location at the destination sample holder. Methods of operating the picking instrument, including calibrating the coordinates of the selected microwell(s) relative to a location of the picking pin, are also provided. [Continued on next page] WO 2018/190907 Al MIDEDIMOMMIDIIMERIDEMIMONIMONERVOIMIE OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))