baber/WOPTO huggingface dataset:
Patent EP-0659439-B1 (EP)
Inventor: HOEGEN ILKA VON
IPC: C07K14/55
Filed: 1994-12-14
Granted: 2001-10-24
Abstract: The present invention relates to new fusion proteins which consist of a tumor-associated targeting element preferentially a monoclonal antibody or a fragment thereof recognizing a molecule which is preferentially expressed on human tumor cells such as the human epidermal growth factor receptor (EGFR), and a biologically active ligand such as a growth and/or differentiation factor. The resulting fusion protein may be used to deliver the biologically active ligand to a specific target cell or tissue. The new immunoconjugates can be used in tumor therapy.
Patent EP-0651221-B1 (EP)
Inventor: VOSS MARK G
IPC: F28D1/053
Filed: 1994-05-27
Granted: 1998-06-24
Abstract: Restrictions on the major dimension of flattened tubes used in heat exchangers employing oval shaped, two piece headers/tank assemblies can be minimized in a construction including a plurality of flattened tubes (14) each having a minor dimension and a major dimension transverse thereto and extending in spaced parallel relation. Fins (16) are in heat exchange relation with the tubes (14) and a pair of spaced, parallel, elongated headers/tank assemblies (10, 12) are provided between which the tubes (14) extend. At least one of the headers/tank assemblies (10, 12) is a multiple piece header/tank assembly including a header piece (20) and a separate tank piece (22). The header piece (20) is elongated and provided with a plurality of slots (28) sized to receive ends of the tubes (14) with the tube major dimensions being generally transverse to the direction of elongation of the header piece (20). The header piece further includes a peripheral flange (24). The tank piece (22) is elongated, concave and has a peripheral flange (44) nested within the peripheral flange (22) of the header piece (20). <IMAGE>
Patent EP-0638638-B1 (EP)
Inventor: ERILLI RITA
IPC: C11D1/74
Filed: 1994-07-08
Granted: 1997-06-18
Abstract: A high foaming, nonionic surfactant based, light duty liquid detergent with desirable cleansing properties and mildness to the human skin comprising: a water soluble nonionic surfactant; at least one water soluble or dispersible foaming, anionic surfactant; a zwitterionic betaine surfactant, and a dialkyl sulfosuccinate ester.
Patent EP-0666439-B1 (EP)
Inventor: LOPEZ CARRION FRANCISCA
IPC: F16K5/06
Filed: 1994-02-07
Granted: 1998-11-18
Abstract: The invention relates to improvements made in a drive shaft for fluid flow valves, of the type comprising an integral body (1), forming the shaft (2) and the valve (3) which is traditionally spherical. The improvements contemplate a sensibly elongate form for the valve (3) relative to the axis of symmetry of the part (1), which provides a surface (4) which is not perfectly spherical, to form a better seat for the seal (5) situated in the valve body outlet pipe. The invention is applicable to fluid flow valves in general and is devised to prevent them from leaking. <IMAGE>
Patent EP-0627164-B1 (EP)
Inventor: ZEUN RONALD DR
IPC: A01N47/38
Filed: 1994-05-26
Granted: 1996-07-17
Abstract: A mixture of N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]imidazole-1-carboxamide (= prochloraz) or of a salt or metal complex thereof, and 4-cyclopropyl-6-methyl-N-phenyl-2-pyrimidineamine (= cyprodinil) or a salt or a metal complex thereof, leads to a synergistically enhanced activity in the control of plant diseases. Such compositions are particularly suitable for controlling plant diseases in cereals. The two active substances can also be applied to the crops individually, one immediately after the other.
Patent EP-0662472-B1 (EP)
Inventor: DUERR DR DIETER
IPC: C07C333/28
Filed: 1994-12-20
Granted: 1998-03-11
Abstract: Sulphonyloxy-substd. benzophenone hydrazone derivs. of formula (I) and their salts are new: R1, R17 = halo; 1-8C alkyl or alkylthio opt. substd. by halo; Ph; OPh; SPh; 1-8C alkylcarbonyl;etc.; m = 0-4; n - 0-5; X = S, R2 = R21 or H and R3 = R31, -NR5R6 or -OR2; or X = O, R2 - R21 and R3 = R31; or X = O, R2 = H and R3 = R8OR9, -R8OCOR9, -R8NR10R11 or =R8R12; or X and R3 together form R18; Y = O or S; R4 = 1-8C alkyl opt. substd. by halo; or halo- 1-8C alkoxy; R21 = 1-8C alkyl opt. substd. by halo; 1-4C alkyl substd. by 1-4C alkoxy,etc.;R31 = H; 1-8C alkyl opt. substd. by halo;etc.;R5, R6 = H; 1-8C alkyl opt. substd. by halo;etc.;R7 = H; 1-8C alkyl opt. substd. by halo; or 2-8C alkenyl; R8 = C(R15R16)p; p = 1-4; R9 = 1-8C alkyl; halo-substd. alkyl or alkenyl with up to 11C;etc.;R11 = 1-8C alkyl,etc.;R12 = satd. or unsatd 5- or 6 membered heterocyclic or heterobicyclic ring contg. 1-3 O, N and/or S atoms,etc.;R13, R14 = H or 1-8C alkyl; R15, R16 = H, 1-8C alkyl;etc.;R18 = NC(R19)=C(R19)Y;etc.;R19 = H; halo; or 1-4C alkyl opt. substd. by halo;cpds. (I) are excluded when R2 = H and (a) m = 0, n = 1, R1 = 4-Cl, R3 = -N(OMe)Me or -NHNH2, R4 = CF3 and X = O; or (b) m = 0, n = 2, R1 = 3,4-diCl, R3 = -N(OMe)Me, R4 = CF3 and X = O.
Patent EP-0635160-B1 (EP)
Inventor: CHEN HSING-YAO
IPC: H01J29/48
Filed: 1993-11-19
Granted: 1999-01-13
Abstract: A multi-beam electron gun (60) for a color cathode ray tube (CRT) includes a plurality of vertically spaced, horizontal inline beams, where each inline array of beams provides the three primary colors and adjacent inline beam arrays simultaneously trace adjacent horizontal scan lines (72a, 72b), where each inline array of beams provides three primary colors and adjacent inline beam arrays simultaneously trace adjacent horizontal scan lines (83a, 83b) on the color CRT's display screen (61). Each inline array of beams is modulated in accordance with that portion of the video image which they form allowing adjacent, vertically spaced inline arrays to write different video image information on the screen in simultaneously forming adjacent portions of the color video image. Simultaneously providing color video image information on more than one horizontal scan line allows for a reduction in horizontal scan frequency and associated magnetic deflection yoke operating criteria, and also increases beam dwell time on the screen's phosphor elements allowing for a reduction in individual beam current without sacrificing video image brightness while improving video image resolution.
Patent EP-0679235-B1 (EP)
Inventor: FELLOWS THOMAS GEORGE
IPC: F16H37/08
Filed: 1994-01-12
Granted: 1997-04-02
Abstract: Transmission à rapport variable en continu (TVC), par exemple du type à traction à roulement et à piste toroïdale, possédant une position neutre et pouvant fonctionner selon au moins deux régimes. Cette transmission comprend un composant à rapport variable (le variateur) (4), un arbre d'engrenages epicycloïdal (E) à récupération de puissance, un arbre à entraînement final (I) pouvant être relié au variateur (4) à l'aide de l'un des deux arbres à entraînement alterné (A, B) et un train epicycloïdal d'entrée (e), dont l'entrée (35) peut être reliée à un mécanisme primaire (3) et dont les deux sorties (36, 40) sont respectivement reliées aux deux arbres à entraînement alterné (A, B). L'un des régimes de fonctionnement comprend une position neutre et le train d'engrenages epicycloïdal (E) à récupération de puissance est associé à des embrayages (44, 46) permettant à ce régime le renvoi de puissance à travers ledit train d'engrenage epicycloïdal (E). Le ou les autres régimes restants ne permettent pas le renvoi de puissance par ce train d'engrenages epicycloïdal (E), mais elle est transmise à la sortie (1) de la TVC, à travers des embrayages appropriés (44, 46, 48, 47, 49, 45), l'un ou l'autre des arbres entraînés (A, B) voyant alors sa vitesse augmenter.
Patent EP-0714451-B1 (EP)
Inventor: SADJINA HEINZ
IPC: C21B5/00
Filed: 1994-02-14
Granted: 1998-06-17
Abstract: PCT No. PCT/EP94/00415 Sec. 371 Date Feb. 26, 1996 Sec. 102(e) Date Feb. 26, 1996 PCT Filed Feb. 14, 1994 PCT Pub. No. WO95/06139 PCT Pub. Date Mar. 2, 1995A method is provided for the disposal and utilization of sorted-out gas cylinders filled with fillers. The method is characterized in that the gas cylinders, together with the fillers contained therein, are supplied as charge in the degasified, opened condition as a whole or comminuted into large pieces, to an iron melting furnace, in particular a cupola furnace, a blast furnace or a rotary drum type furnace.
Patent EP-0690826-B1 (EP)
Inventor: HERDING WALTER
IPC: B29C48/35
Filed: 1994-03-24
Granted: 1998-02-11
Abstract: PCT No. PCT/EP94/00945 Sec. 371 Date Sep. 22, 1995 Sec. 102(e) Date Sep. 22, 1995 PCT Filed Mar. 24, 1994 PCT Pub. No. WO94/21566 PCT Pub. Date Sep. 29, 1994A fixed-bed bioreactor with porous carrier bodies (14) for microorganisms. The carrier bodies are sheet-like structures with a small thickness in comparison with the carrier body surface. The carrier bodies are kept spaced apart by means of spacing bars (28), defining flow paths (36) between the carrier bodies. In a process for producing porous carrier bodies for microorganisms, plastics particles (70) are introduced into a moulding space (52) and bonded together therein by application of heat. With this process, an endless extrudate (46) of carrier body material may be produced, from which the individual carrier bodies may be cut off. Alternatively, the process may be carried out by means of a series of pairs of mould halves passing through a mould filling station and a heat supply station.
Patent EP-0699172-B1 (EP)
Inventor: PARE FRANCOIS
IPC: B01D53/84
Filed: 1994-05-18
Granted: 1997-10-08
Abstract: Bioréacteur pour le traitement biologique aérobie des eaux usées et des effluents gazeux contaminées par des hydrocarbures, comprenant une chambre de traitement biologique (20) consistant en un compartiment vertical (22) muni d'une porte d'accès et dont les parois, le plancher et le plafond délimitent ladite chambre. La chambre (20) est munie de moyens d'introduction des eaux usées (35, 36) déversées sous pression depuis sa partie supérieure sur une série de plateaux (60, 62, 64) de traitement des eaux disposés sensiblement à l'horizontale à l'intérieur de la chambre et conçus pour recueillir les eaux introduites. Chacun desdits plateaux présente au moins une partie basse poreuse (66) destinée à recevoir des substances de contact (68). La chambre de traitement comporte également un orifice d'évacuation des eaux (57) disposé sensiblement à sa base, des moyens d'aération (240) y créant un environnement en faisant circuler un courant d'air à travers les plateaux, et un orifice d'évacuation de l'air (230) introduit dans le réacteur par les moyens d'aération.
Patent EP-0701561-B1 (EP)
Inventor: CARGANICO GERMANO
IPC: C07F9/09
Filed: 1994-05-18
Granted: 1998-08-19
Abstract: The invention relates to a series of novel desoxyazaphospholipid derivatives which exhibit inhibiting activity on phospholipase A2, the pharmaceutically acceptable salts thereof, a process for the preparation thereof, pharmaceutical compositions containing said compounds, and the use thereof in therapy.
Patent EP-0770387-B1 (EP)
Inventor: TOLEDO ALFONSO
IPC: A61K31/445
Filed: 1995-10-28
Granted: 1999-08-11
Abstract: The present invention relates to a pharmaceutical composition in the form of an oil-in-water emulsion (o/w) consisting essentially of   (a) 5 to 30% (w/v) of an oily carrier consisting of long-chain triglycerides (LCT) and/or medium-chain triglycerides (MCT),   (b) 0.5 to 2% (w/v) of an emulsifier, (c) 0.1 to 2% (w/v) of a local anesthetic and/or centrally acting analgesic, (d) conventional additives. rm
Patent EP-0705818-B1 (EP)
Inventor: HIVER PATRICIA NATHALIE
IPC: C10M135/30
Filed: 1995-09-14
Granted: 1998-10-07
Abstract: New cpds. are of the general formula (I): R = alkyl, tert. alkyl, benzyl or allyl (opt. functionalised); R' and R" (similar or different) = H, alkyl or tert. alkyl (opt. functionalised); x = 1-5; n = 1-25, - are claimed. Also claimed are their methods of synthesis and use in lubricating compsns. to form aq. emulsions.
Patent EP-0739428-B1 (EP)
Inventor: REGHI GARY A
IPC: C23C22/34
Filed: 1994-11-23
Granted: 1999-10-13
Abstract: Cette invention a pour objet une composition de traitement liquide, aqueuse, dépourvue de chromate qui est chimiquement et thermiquement stable, utilisée pour traiter des métaux, plus particulièrement de l'aluminium, et qui confère aux métaux une résistance à la corrosion aussi bonne que celle résultant des traitements classiques à l'aide de compositions contenant du chromate. Cette composition est constituée d'eau et de: (A) un constituant sélectionné dans le groupe formé par H2TiF6, H2ZrF6, H2HfF6, H2SiF6, H2GeF6, H2SnF6, HBF4 et des mélanges de ces dernières; et (B) un constituant sélectionné dans le groupe formé des acides carboxyliques organiques solubles dans l'eau qui contiennent au moins deux groupes hydroxyle, sans compter les groupes hydroxyle qui font partie de groupes carboxyle, par groupe carboxyle dans chaque molécule d'acide; des sels solubles dans l'eau, et des mélanges d'au moins deux de ces acides et sels; et, facultativement d'au moins un de ces constituants: (C) un constituant sélectionné dans le groupe formé par Ti, Zr, Hf, Al, Si, Ge, Sn et B, les oxydes, les hydroxydes et les carbonates de Ti, Zr, Hf, Al, Si, Ge, Sn et B, et des mélanges d'au moins deux de ces éléments, oxydes, hydroxydes et carbonates; (D) un constituant sélectionné dans le groupe formé par les polymères et copolymères, pouvant se dissoudre ou se disperser dans l'eau, d'un ou plusieurs x-(N-R1-N-R2-amino-méthyl)-4-hydroxy-styrènes, dans lesquels x = 2, 4, 5 ou 6, R1 représente un groupe alkyle contenant de 1 à 4 atomes de carbone, et R2 représente un groupe de substitution se conformant à la formule générale H(CHOH)¿N?CH2-, dans laquelle n représente un entier compris entre 1 et 7; (E) un constituant d'ajustement du pH sélectionné dans le groupe formé par les acides inorganiques et les matières alcalines inorganiques qui ne contiennent pas de fluor; (F) un constituant sélectionné dans le groupe formé par les acides inorganiques qui contiennent du fluor mais aucun des éléments suivants: Ti, Zr, Hf, Al, Si, Ge, Sn et B; et (G) une quantité suffisante pour réduire la mousse d'un constituant à base d'agent antimousse.
Patent EP-0736050-B1 (EP)
Title: Moisture-curable modified acrylic polymer sealant composition
Inventor: KOZAKIEWICZ WALDEMAR
IPC: C08F220/06
Filed: 1994-12-22
Granted: 1998-10-07
Abstract: A crosslinkable acrylic copolymer sealant composition has a stabilized viscosity in that the viscosity does not unduly increase nor does the material gel on storage for periods of time up to and including one year. The stabilized viscosity is unexpectedly achieved by adding moisture scavengers either before and/or during the polymerization of the various monomers. The sealant composition is suitable for use in high movement applications as well as to metal and glass substrates.
Patent EP-0694205-B1 (EP)
Inventor: VENZKE DONALD R
IPC: H01H71/50
Filed: 1995-02-13
Granted: 1998-09-23
Abstract: A latch mechanism for a circuit breaker comprises a pair of longitudinal legs, a lateral section bridging the pair of longitudinal legs, and a longitudinal section extending from the lateral section in an opposite direction relative to the pair of legs. The lateral section includes a lower bearing surface for releasably engaging a cradle of the circuit breaker. The lower bearing surface includes a coined radius for facilitating engagement and disengagement of the cradle. The longitudinal section includes a protrusion for supporting a latch spring. The latch mechanism is manufactured in a single stamping operation, during which the protrusion is formed by cold extrusion.
Patent EP-0754045-B1 (EP)
Inventor: CHARMAN WILLIAM NEIL
IPC: A61K47/44
Filed: 1995-04-04
Granted: 2002-03-06
Abstract: The present invention relates to the use of halofantrine free base in the treatment of malarial infections. In particular, lipid-based formulations for oral and injectable use are disclosed.
Patent EP-0758496-B1 (EP)
Inventor: FREY RUDOLPH W
IPC: H01S3/225
Filed: 1995-04-18
Granted: 2002-10-30
Abstract: A new cartridge excimer laser system and method for generating an excimer laser beam using the system are provided. The system utilizes a cartridge (10) which contains a halogen-noble gas mixture (19), electrodes (50, 60) having external electrical connections (30, 40), and assembly (20) for transmitting a laser beam output (400), and an external gas port (90). The cartridge (10) fits onto a receptacle (100) located within a receiving compartment (200) of the laser base (300) of the new system. The cartridge (10) is easily replaced by the system operator and is refurbished by the manufacturer when the gas mixture (19) therein is exhausted.
Patent EP-0758452-B1 (EP)
Inventor: DENNIS JAMES W
IPC: A61P11/00
Filed: 1995-05-04
Granted: 2001-11-07
Abstract: The invention relates to a method for assaying for the presence of a substance that modulates a cytokine of the TGF beta  superfamily. A substance which is suspected of modulating a cytokine of the TGF beta  superfamily and a TGF beta  binding compound which is not a TGF beta  receptor and which contains a TRH1 domain, or a portion or mimetic thereof, is reacted with a cytokine of the TGF beta  superfamily under conditions where the compound, portion or mimetic thereof, and the cytokine are capable of forming a complex. Complexes, free compound and/or cytokine are assayed and compared with a control. The invention also relates to a composition comprising at least one compound which is not a TGF beta  receptor and which contains the TRH1 domain or a portion, or a mimetic thereof, and a pharmaceutically acceptable carrier, auxiliary or excipient and to methods of treatment using the composition. Further the invention relates to a method of enhancing the activity of growth factors.
Patent EP-0760901-B1 (EP)
Inventor: TRAENKER HAGEN
IPC: E21C35/183
Filed: 1995-05-08
Granted: 1997-10-22
Abstract: L'invention concerne un dispositif d'assujettisement pour outil d'exploitation, en particulier un fleuret à taillant simple utilisé pour extraire de la matière brute par abattage coupant ou rabottage ou bien pour couper de la roche. Ledit dispositif comprend un corps (1) pourvu d'une poche dans laquelle se loge l'outil d'exploitation, et il est relié à une machine d'exploitation ou de percement, l'usure sur le corps (1) étant réduite au minimum, de façon que sa vie utile soit plus longue, grâce au fait qu'il présente, dans la région de ses surfaces principales d'usure, un nombre d'éléments antiusure (4) qui font saillies à partir du corps (1) et qui sont fixés dans des évidements (5) ménagés dans celui-ci.
Patent EP-0772442-B1 (EP)
Inventor: SHINITZKY MEIR
IPC: A61K31/52
Filed: 1995-06-13
Granted: 2002-05-02
Abstract: PCT No. PCT/EP95/02289 Sec. 371 Date Jan. 13, 1997 Sec. 102(e) Date Jan. 13, 1997 PCT Filed Jun. 13, 1995 PCT Pub. No. WO95/34306 PCT Pub. Date Dec. 21, 1995A pharmaceutical composition for the treatment of schizophrenic disorders that comprises a pharmaceutically acceptable carrier and as active ingredient an immunosuppressive agent.
Patent EP-0772773-B1 (EP)
Inventor: SPARKS ANDREW B
IPC: C07K7/08
Filed: 1995-07-24
Granted: 2006-04-05
Abstract: Peptides having general and specific binding affinities for the Src homology region 3 (SH3) domains of proteins are disclosed in the present invention. In particular, SH3 binding peptides have been isolated from three phage-displayed random peptide libraries which had been screened for isolates that bind to bacterial fusion proteins comprising SH3 and glutathione S-transferase (GST). Preferred peptides are disclosed which comprise a core 7-mer sequence (preferably, a consensus motif) and two or more, preferably at least six, additional amino acid residues flanking the core sequence, for a total length of 9, preferably at least 13, amino acid residues and no more than about 45 amino acid residues. Such peptides manifest preferential binding affinities for certain SH3 domains. The preferred peptides exhibit specific binding affinities for the Src-family of proteins. In vitro and in vivo results are presented which demonstrate the biochemical activity of such peptides.
Patent EP-0793522-B1 (EP)
Inventor: BOLLI PETER
IPC: A63H3/44
Filed: 1995-11-20
Granted: 1999-06-16
Abstract: PCT No. PCT/EP95/04569 Sec. 371 Date May 21, 1997 Sec. 102(e) Date May 21, 1997 PCT Filed Nov. 20, 1995 PCT Pub. No. WO96/15839 PCT Pub. Date May 30, 1996Threads of hair are embroidered in loops on a flat, flexible base, for example, a textile base, in an area bounded by a desired wig contour. Individual threads or tufted multiple threads are embroidered in loops. Thereafter, the embroidered area is removed from the base along with the wig contour by cutting or punching. The flexible wig is glued onto a doll's head, cut to length and combed.
Patent EP-0745725-B1 (EP)
Inventor: BENTELE RAINER
IPC: D21G1/00
Filed: 1996-05-28
Granted: 2000-07-26
Abstract: Roller press, calender etc. has three rollers min. forming pressure gaps to process fabric web (2) where one (3) has a very flexible casing rotating about a fixed carrier (4) on which it is mounted via at least one support element (6) with a concave surface (7) guaranteeing a broad pressure gap (1) with a counter cylinder (8). The latter forms another gap (15) with at least one flexurally non-controlled roller (14) and its casing's (9) outer circumference reduces axially from roller mid-point to ends. Also claimed is a like second roller press where the feature of the counter roller's casing is that it rotates about a fixed carrier (10) and, at its ends can not be moved against, but is mounted via at least one support element (11) on, the carrier. The elements act in a direction which, while being set at an insignificant angle,  DELTA , out of the pressure plane formed with the first roller (3), is tilted w.r.t. the third roller forming the other pressure gap. Also claimed is third roller press similar to the last where the feature of the counter roller's support elements is that, along with the opposing main roller elements (6), they are so arranged and activated that the main roller exerts greater resultant compressive force in opposing that from the counter roller. Pref. the circumference of the main roller's casing and of the third roller reduces axially from roller mid-point to ends by pref. the same amount. All rollers circumferences taper off similarly to those of the preferred first press. Alternatively the counter roller's circumference does not alter. Angle  DELTA  is between 2 and 15, pref. 4 and 8 degrees and varies from roller mid-point to ends. All roller circumferences of taper off similarly to those of the preferred second press, angle  DELTA  has the same features and support elements are similarly tilted. Opposing support elements are singly, in groups or all together connected to a common pressurised fluid pipe. It is guaranteed that the main roller exerts greater compression in opposing counter roller force by fluid pressure reducing devices and the ratio of the areas of the opposing support elements.
Patent EP-0749235-B1 (EP)
Inventor: KOECHEL MATTHIAS
IPC: H04N3/30
Filed: 1996-06-04
Granted: 2001-11-28
Abstract: The image screen device has a horizontal deflection circuit providing a deflection current for a horizontal deflection coil, for symmetrical deflection of the electron beam, with a memory for temporary storage of the displayed signal, coupled to a memory control circuit. The latter includes a read clock generator (4) providing a read clock with a period duration which is variable within each line duration. A variable amplifier (3) provides a cathode beam current which is reduced in dependence on a reduction in the horizontal velocity of the electron beam during its movement across the screen for each line.