baber/WOPTO huggingface dataset:
Patent HU-9300098-D0 (HU)
Title: Method for producing expression vector of dictyostelide and for producing protein thereby
Inventor: FASEL NICOLAS JOSEPH
IPC: C12P21/08
Filed: 1992-05-18
Abstract: The invention relates to recombinant DNA molecules comprising a Dictyostelium discoideum homologous promoter region, a heterologous DNA sequence with a Dictyostelium discoideum homologous peptide sequence capable of functioning as a leader peptide sequence positioned upstream thereof and in proper reading frame therewith, and a Dictyostelium discoideum homologous termination region, the heterologous DNA sequence encoding the desired functional polypeptide or intermediate thereof, said DNA sequence being positioned downstream from the promoter region and said termination region being positioned downstream from the DNA sequence. The invention also provides recombinant dictyostelid hosts as well as methods for preparing recombinant DNA molecules of the invention and for expressing recombinant polypeptides encoded by said recombinant DNA molecules in dictyostelid hosts. The invention in particular relates to the expression of the CS protein of Plasmodium falciparum.
Patent HU-9302515-D0 (HU)
Title: Process for making amine isomeres recirculate
Inventor: ADAMI MARCO
IPC: C07C211/42
Filed: 1992-02-07
Abstract: A novel process for converting trans-isomeric N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine to cis-isomeric N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine is disclosed. The process involves contacting trans-isomeric N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine, or a mixture of same with up to about an equal part by weight of the corresponding cis-isomer, with a basic equilibration agent like potassium tert.-butoxide in a reaction-inert polar organic solvent to ultimately afford a cis/trans-mixture wherein the amount of cis-amine present in said mixture achieves a constant value of about 2:1 on a weight-by-weight basis. The aforesaid resultant mixture is useful as an intermediate product that ultimately leads to pure cis-(1S) (4S)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenea mine (sertraline), which is a known antidepressant agent.
Patent HU-9502710-D0 (HU)
Title: Method for the preparation of 3-hydroxy-5-[2-(dimethylamino)-ethyl]-2,3-dihydro-4-(methoxyphenyl)-1,5-benzothiazepin-4(5h)-one and use of the product for making pharmaceutically active compounds
Inventor: HYTOENEN MARTTI
IPC: A61K31/55
Filed: 1995-09-15
Abstract: A method for the preparation of 3-hydroxy-5-Ä2-(dimethylamino)-ethylÜ-2,3-dihydro-4-(methoxyphenyl)-1, 5-benzothiazepin-4(5H)-one and use of the product prepared by this method for making pharmaceutical compositions and pharmaceutically active compounds is disclosed starting with N-alkylation of 3-hydroxy-2,3-dihydro-4-(methoxyphenyl)-1,5-benzothiazepin-4(5H)-one with a (dimethylamino)ethyl halide wherein the N-alkylation reaction is carried out in a reaction mixture comprising 2-butanone and water. The product of this reaction and its salts have utility as pharmaceutically active compounds and as intermediates for making pharmaceutically active compounds. The disclosed method and use is simpler, more efficient and safer than prior known methods and produces a product of superior purity.
Patent HU-9503708-D0 (HU)
Title: Novel processes for preparing (s)-4-amino-hepta-5,6-dienoic acid and intermediates thereof
Inventor: KOLB HANS MICHAEL
IPC: C07C227/22
Filed: 1994-05-23
Abstract: The present invention relates to a novel enantiospecific processes for preparing (S)-4-amino-hepta-5,6-dienoic acid and pharmaceutically acceptable salts thereof, which is useful as an irreversible inhibitor of GABA-T, to novel intermediates thereof, and a process for preparing an intermediate thereof.
Patent HU-9600195-D0 (HU)
Title: Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca
Inventor: KOEKMAN BERTUS PIETER
IPC: C12N9/00
Filed: 1994-07-29
Abstract: PCT No. PCT/EP94/02544 Sec. 371 Date May 13, 1996 Sec. 102(e) Date May 13, 1996 PCT Filed Jul. 29, 1994 PCT Pub. No. WO95/04149 PCT Pub. Date Feb. 9, 1995An overall efficient process for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via 3-(carboxyethylthio)propionyl-7-ADCA, using a Penicillium chrysogenum transformant strain expressing expandase in conjunction with acyltransferase, is provided.
Patent HU-9900838-D0 (HU)
Title: Process for continuous producing of silicone copolymers
Inventor: AUSTIN PAUL E
IPC: C08L83/05
Filed: 1999-03-31
Abstract: Disclosed is a continuous process for producing silicone copolymers using a series of at least one stirred-tank reactor, the last of which reactor in said series has crude product stream feeding into at least one plug flow reactor, wherein this crude product stream is sufficiently homogeneous such that this stream which undergoes further reaction in the plug flow reactor does not undergo phase separation.
Patent IT-8619421-D0 (IT)
Inventor: BORDINI GIORGIO
IPC: B65B55/02
Filed: 1986-02-14
Abstract: In packing machines which produce aseptic packing contain­ers for e.g. foodstuffs, it is of greatest importance that the machines can be cleaned and sterilized in a satisfactory manner prior to the production of packing containers. In accordance with the invention a method and an arrangement are provided on a packing machine for the sterilization of the lower end of a filling pipe l0 as well as of surrounding parts of a packing material tube 8. Use is made for this purpose of a connecting element 20 which connects two feed ducts ll,l2 present in the filling pipe l0 to each other so that cleaning and sterilizing agent can circulate in the filling pipe. In a subsequent stage the connecting element 20 is removed so that sterilizing agent can be made to circulate also along the outside of the filling pipe l0 and in the packing material tube surrounding the filling pipe, whereupon the production of the packing containers commences.
Patent IT-8220757-D0 (IT)
Inventor: GRAZIA ALDO
IPC: C07J51/00
Filed: 1982-04-15
Abstract: A new composition consisting of the double magnesium salt of chenodeoxycholic acid and ursodeoxycholic acid, prepared by reacting a magnesium alcoholate with chenodeoxycholic acid, and reacting the resultant product with ursodeoxycholic acid. The new compound is employed as a drug useful in dissolving bile calculi and preventing their formation.
Patent IT-8421948-D0 (IT)
Inventor: HOFFGEN HANS
IPC: B22D41/08
Filed: 1984-07-18
Abstract: A collector nozzle (2) in a device for controlling outflow of cast steel from a ladle or from a tundish, which nozzle incorporates at least one main duct (7) placed ringwise round the outlet passage of the nozzle, a first plurality of secondary ducts (12) connecting each of the above main ducts (17) with a portion of said outlet passage and a second plurality of secondary ducts (13) connecting each of said main ducts (17) with the environment outside the nozzle, at the latter's lower end. The main ducts being filled with a current of inert gas under pressure so that the inert gas reaches the area of said passage where otherwise aluminium oxides would become deposited and immediately outside said nozzle to create overpressure of inert gas, thus preventing air from penetrating through the fissures between the nozzle and the tube protecting the flow of cast steel.
Patent IT-8722485-D0 (IT)
Inventor: CLERICI MARIO GABRIELE
IPC: C07D301/12
Filed: 1987-11-02
Abstract: Process for separately obtaining the stereoisomeric epoxy compounds by starting from mixtures of olefinic compounds of cis- and trans-configuration without resorting to expensive operations of separation of the same isomers, by carrying out the reaction of oxidation of the mixture of stereoisomer olefinic compounds with hydrogen peroxide, or with compounds capable of producing hydrogen peroxide under the reaction conditions, in the presence of synthetic zeolites containing titanium atoms in two successive steps, by operating in a first step with hydrogen peroxide in an amount substantially equal to the amount, by mol, of olefinic compound with cis-configuration which is present in the mixture, separating the so-obtained epoxy compound of prevailingly cis-configuration from the unreacted olefinic compounds, essentially constituted by isomers with trans-configuration, submitting to oxidation, in another reaction area, the unreacted olefinic compound with prevailingly trans-configuration, by operating with hydrogen peroxide in a substantially equimolecular amount relatively to the amount of unreacted olefinic compound.
Patent IT-8422868-D0 (IT)
Inventor: ALBIZZATI ENRICO
IPC: C08F10/00
Filed: 1984-09-27
Abstract: Supported components (component (c)) and the corresponding catalysts for polymerizing olefins, comprising the product of the reaction among :  (a) a metallorganic Al compound; (b) an electron-donor compound reactive towards MgCl2 but not capable of forming complexes with AlEt3 in standard conditions; (c) a solid including a halogenated tetravalent titanium compound and an electron-donor compound, supported on titanium trichloride or tribromide or on vanadium trichloride or tribromide having a surface area of at least 100m<2>/g, the electron-donor compound being characterized in that it is extractable with AlEt3 (under standard conditions) for at least 70% by moles.
Patent IT-8024919-D0 (IT)
Inventor: WOODCOCK MAURICE LUCIEN
IPC: B29C65/00
Filed: 1980-09-25
Abstract: For severing a plurality of hollow fiber membranes comprised of thermoplastic material which membranes are arranged in the form of a bundle and also sealing the bores of the membranes in an essentially fluid-tight manner without any significant decrease in membrane performance or strength, a heated member is passed through the bundle in a path transverse to the orientation of the hollow fiber membranes wherein the temperature of the heated member is above the melt temperature of the hollow fiber membranes. Advantageously, the hollow fiber membranes which are severed have a significant void volume and may be anisotropic with a thin, dense skin. The heated member can be a hot wire or ribbon.
Patent IT-8068392-D0 (IT)
Inventor: COPPO SANDRO MAGAGNA VINCENZO
IPC: B60L15/38
Filed: 1980-09-09
Abstract: Each carriage is equipped with a three-phase two-speed pole-switching induction motor and front and rear shock- absorbers. The track incorporates low-voltage AC supply lines (R.S.T) and a control line, which is divided into isolated sections capable of being interconnected via the carriage. The three control signals are full-wave alternating voltage and the two pulse waveforms produced by suppression of one or other half-wave. A discriminator relay circuit connected to the current collectors in contact with two lines operates the control logic so as to move the carriage at a higher or a lower speed or bring it to rest, in accordance with the control line waveform. Different sections of track can be controlled for different speeds, or the whole can be used as a storage zone.
Patent IT-8682567-D0 (IT)
Inventor: POZZOBON ALESSANDRO
IPC: A63C9/086
Filed: 1986-08-04
Abstract: The binding comprises a front element (4) for the coupling of the boot and a rear device (5) for the removable locking of the boot. The locking device is provided with sliding elements for its translatory motion, against and due to the biasing action of a first elastic member, along the longitudinal axis of the ski (3) and with rotation elements for its oscillation against and due to, the biasing action of a second elastic member, about an axis which is substantially vertical with respect to the base plate (2). The sliding and rotation elements being structured so as to act independently and simultaneously with respect to one another. The boot has a recess in the sole adapted to engage with the front coupling element (4) and being spaced equidistant from the heel regardless of the size of the boot.
Patent SE-0201976-D0 (SE)
Inventor: BAILEY ANDREW
IPC: A61P25/00
Filed: 2002-06-24
Abstract: The present invention therefore provides use of a compound of formula (I) and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition, this invention also discloses processes for the preparation of such inhibitors.
Patent SE-0202425-D0 (SE)
Inventor: SANTESSON PER-OLOF
IPC: E06B7/12
Filed: 2002-08-14
Abstract: The disclosure relates to a profile (4) for defining and framing an opening in a wall and the profile (4) serves as an anchorage for fixed or moving window or wall sections (1, 2, 3). The profile (4) has an outer portion (5) which is turned to face towards the surroundings on the outside of the wall and an inner portion (6) which is turned to face towards a space on the inside of the wall. The inner portion (6) of the profile (4) has a heating device, an electric heating cable, in a pocket (19).
Patent SE-0301149-D0 (SE)
IPC: A61C8/00
Filed: 2003-04-17
Abstract: To anchor a fixture (7) in a jaw bone (1), the fixture is applied in a hole (6) which is substantially smaller than the diameter of the fixture. The fixture has a front portion (7b) which from the point of view of diameter grows very much narrower and which is arranged with both a cutting function and a threading function. The fixture is provided with a thread, with one, two or more thread turns extending down along the greatly narrowing portion while substantially maintaining their thread profile. One or more porous layers arranged on the thread turns can also be included. In this way the fixture can exploit the clamping effect from the soft parts (3) of the jaw bone and still effectively penetrate through any hard parts (4, 5) possibly present in the jaw bone, without these hard parts being pressed inward upon fixture application. An effective fusion of the fixture (7) in the jaw bone (1) is achieved with the aid of said porous outer layers (20).
Patent SE-0302571-D0 (SE)
Inventor: LIU ZIPING
IPC: C07D401/12
Filed: 2003-09-26
Abstract: Compounds of Formulae (IA), (IB) or pharmaceutically acceptable salts thereof; wherein Het, X<SUP>1</SUP>, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>3</SUP><SUB>a </SUB>and R<SUP>4 </SUP>are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
Patent SE-0402071-D0 (SE)
Inventor: BERTILSSON PAER OLOV
IPC: G06Q40/00
Filed: 2004-08-25
Abstract: The invention relates to a method, a central system, an application, and an electronic memory means for a pricing function (20) for derivatives of market maker participants (16). Market makers are electronically addressing the application recalculating the pricing function (20) of the derivatives to an option price for an underlying instrument pricing, having an underlying reference parameter (Ref). The function made up by parameters being approximately constant in an interval. Thus, the function can be approximated as a linear function (22) within the interval. The processing of the function in a trade server (18) reduces the risk in lost time for participants (16) handling with derivatives, and minimizes the processing and the distribution effort at a central system by letting the recalculating of the pricing function (20) be performed at the central system and its application therefore.
Patent SE-0402966-D0 (SE)
Inventor: ASTORGA-WELLS JUAN
IPC: G01N/
Filed: 2004-12-06
Abstract: The present invention relates a use of the electrocapture-based separation technology combined with mass spectrometry (e.g. sequence of polypeptides by collision-induce dissociation mass spectrometry, for the identification and/or characterization molecules of interest). In addition, it relates physical interfaces between electrocapture-based separations and different types mass spectrometers for on-line analysis, as well as the coupling of electrocapture-based separations, liquid chromatography and different types of mass spectrometers. It also relates the combination of the electrocapture-base separation technology with other liquid separation methods, as e.g. liquid chromatography, in order to achieve multidimensional separations prior mass spectrometrical analysis. The invention also relates to a separation device comprising a capture device, a fluidic connector e.g. an electrospray source, an electrospray interface-source and a mass spectrometer.
Patent SE-8205186-D0 (SE)
Inventor: STERTE R
IPC: F16B2/14
Filed: 1982-09-13
Abstract: PCT No. PCT/SE83/00321 Sec. 371 Date May 14, 1984 Sec. 102(e) Date May 14, 1984 PCT Filed Sep. 12, 1983 PCT Pub. No. WO84/01193 PCT Pub. Date Mar. 29, 1984.A clamping device with an improved attachment of a component (3) inserted in a hole (2) has a casing (5) of a deformable material arranged in a recess (4) in the end of the component and a V-shaped notch open towards the end of the component, a wedge (10) inserted in the notch with its longitudinal direction parallel to the end surface of the component, a screw (12) engaging in a threaded hole (11) through the wedge and extending through a hole (13) through the casing, the wedge being pressed down into the notch of the casing by the screw thereby displacing parts of the casing located around the notch towards parts of the component located on both sides of the recess (4) so that the latter parts are pressed towards the wall of the hole at right angles to the longitudinal direction of the wedge. By the arrangement according to the invention of the two holes (11, 13) through the wedge and the casing at an angle to the longitudinal direction of the wedge, tightening the screw will draw the wedge down into the notch and at the same time be displaced in its longitudinal direction with one end (17) against the wall in the hole (2), into which the component (3) is inserted in a direction perpendicular to the direction in which the wedge presses the parts of the component against the wall of the hole, which parts are located on both sides of the recess (4).
Patent SE-8205255-D0 (SE)
Inventor: SUNDMAN F V
IPC: B30B9/20
Filed: 1982-09-14
Abstract: Press for removing water, wherein the material to be treated is led together with a wire which is pervious to water through a press nip zone formed by opposite surfaces. The press comprises compressible means for transporting the material to be treated. This means runs through the press nip and comprises several compression chambers which open out against the wire pervious to water. The compression chambers are preferably made so that they expand towards the water transmitting wire or felt, e.g. like a truncated pyramid.
Patent SE-8302669-D0 (SE)
Inventor: GIEBER GUNTER
IPC: B60R9/12
Filed: 1983-05-10
Abstract: A roof rack securable to the rain gutters of a motor-vehicle roof above the door openings has a leg subassembly with a support, a leg standing in the gutter above the respective door opening and carrying the support, and the leg is secured to the respective gutter. A holddown member is pivoted on the support and displaceable between a locking position close to same for securing an object to the support and a freeing position spaced from the support. A locking element extends into the respective door opening underneath the leg and is vertically displaceable relative thereto between an upper position relatively close underneath the respective gutter and a lower position spaced downward therefrom. Thus the locking element can only move into the respective lower position when the respective door is not closed in the respective door opening. A latch is provided including formations engageable in the upper position of the locking element and connected to the holddown member for preventing displacement of same into the freeing position except when the locking element is in the lower position.
Patent SE-8304706-D0 (SE)
Inventor: STAHL B
IPC: B23B31/30
Filed: 1983-08-31
Abstract: A quick-acting clamping device for clamping tools or workpieces in machine tools comprises a piston which is slidable transversely to the clamping direction and which acts on a toggle mechanism which in turn moves a clamping piece. A pressure plate upon which the toggle mechanism acts is displaceable in the clamping direction in a housing which contains the transverse piston. The fluid under pressure which acts on the transverse piston to activate the toggle mechanism also acts directly on the pressure plate to assist in clamping. Because of the assisting force produced by the pressure plate it is possible for the transverse piston to move the members of the toggle mechanism from starting positions in which they lie at large angles to the clamping direction, that is with a big angular displacement from their dead-center position, in which they initially exert only a small force on the clamping piece. Because of this large angular displacement of the members of the toggle mechanism, the toggle mechanism by itself can produce a large linear movement of the clamping piece.
Patent SE-8502085-D0 (SE)
Inventor: SUNDBERG DAN
IPC: B21D37/00
Filed: 1985-04-29
Abstract: The gap between the side members is adjustable in steps. To set it, the side member are raised by cylinders, and after adjustment, they are lowered. Tere are sensors at the bottom of gap. Their setting can be adjusted coarsely with the device and finely, electronically. The camber of the side members can be changed with the adjustment screw.
Patent SE-8503905-D0 (SE)
Inventor: KEOUGH K E
IPC: G03F7/16
Filed: 1985-08-21
Abstract: A device and method for accurately dispensing liquid photopolymer in accurate predetermined configuration to form a printing plate blank. The device gravity feeds the photopolymer from a first manifold through capillary tubes to a second manifold machined in an elongated member together with a doctor blade portion, laying down a carefully sculptured sheet. The sheet is formed into a printing plate upon exposure to actinic light through an indicia carrying negative. The invention may have other applications.
Patent SE-8505343-D0 (SE)
Inventor: HA J Y
IPC: B60W10/18
Filed: 1985-11-12
Abstract: An automatic control circuit for a brake control device, relays around the device, light lamps and other parts to be operated differently under different circumstances, e.g., braking while running, braking to stop, releasing the brake pedal after braking, starting, parking after braking, and operation when the car stops in semi-automatic. The automatic control circuit operates a valve in the hydraulic system which isolates the system after hydraulic pressure is increased, thus maintaining braking pressure even when the brake pedal is released. The valve isolates the hydraulic system until the clutch pedal is released and the accelerator pedal is depressed, then the valve is allowed to open and pressure is released. A vehicle movement detector is coupled to the circuit which ensures that brake pressure will not automatically be maintained when the vehicle is moving. The vehicle movement detector is also capable of controlling a headlight relay so that current to the headlights is cut off when the vehicle is stationary, but current is allowed to pass to the headlights when the vehicle is in motion. The automatic control circuit is also capable of operating brake lights, pilot light and parking lamps.