baber/WOPTO huggingface dataset:
Patent CA-2976889-A1 (CA)
Title: Quinuclidine derivative
Inventor: MIZUSHIMA TOHRU
IPC: A61P43/00
Filed: 2016-02-25
Abstract: Provided is a new agent for treating chronic obstructive pulmonary disease. The present invention provides quinuclidine derivatives represented by general formula (1), and a pharmaceutical containing the same. (In the formula, R1 indicates a hydrogen atom, halogen atom, lower alkyl group, haloalkyl group, lower alkoxy group, or haloalkoxy group; Y indicates -C(C=O)-O-, -CH2-, or -CH2O-; m indicates an integer of 1-5; Z indicates an oxygen atom or sulfur atom; l indicates 0 or 1; n indicates an integer of 0-4; X- indicates an anion; and the substituent of the quinuclidine ring indicates a 1,3-bond or 1,4-bond. However, when m is 3, l is 1, and n is 0, R1 indicates a halogen atom, lower alkyl group, haloalkyl group, lower alkoxy group, or haloalkoxy group.)
Patent CA-2977261-A1 (CA)
Inventor: CLAUSEN HENRIK
IPC: C07K16/28
Filed: 2007-10-04
Abstract: The present invention provides a method for inducing a cancer specific immune response against MUC1 using an immunogenic glycopeptide. Other aspects of the invention are a pharmaceutical composition comprising the immunogenic glycopeptide and a cancer vaccine comprising the immunogenic glycopeptide. Another aspect is an antibody generated using the immunogenic glycopeptide and the use of said antibody in therapy and diagnosis.
Patent CA-2978468-A1 (CA)
Title: Procede de controle d'un cordon de soudure a l'aide d'un reseau ultrasonore pilote en phase
Inventor: ININGER JORG
IPC: G10K11/34
Filed: 2016-02-17
Abstract: L'invention concerne un procédé de contrôle non-destructif d'un cordon de soudure. Un réseau de transducteurs à ultrasons est positionné de telle sorte que le réseau de transducteurs s'étend sur au moins une partie de la largeur du cordon de soudure. Chaque élément transducteur dans le réseau d'éléments transducteurs est excité de sorte que chaque transducteur émet un signal ultrasonore. Une pluralité de signaux ultrasonores réfléchis sont reçus au niveau du réseau d'éléments transducteurs et les signaux ultrasonores réfléchis sont transformés en signaux électriques. Les signaux électriques sont analysés pour identifier un défaut, ou une pluralité de défauts.
Patent CA-2980696-A1 (CA)
Title: Tubular container
Inventor: YOSHIDA MIHOKO
IPC: B65D35/10
Filed: 2016-04-06
Abstract: [Problem] To provide a tubular container which has non-stick properties with respect to content and gas barrier properties. [Solution] A tubular container 1 provided at least with: an outlet unit 20 that has an outlet part 21 through which the content is sent out and a shoulder part 24 that radially extends outward from the outlet part 21; and a body part 10 that is fused to the shoulder part 24 of the outlet unit 20 and stores the content therein, wherein the body part 10 has at least an innermost layer that is made of a non-stick resin and formed on the inner side that comes into contact with the content, an outermost layer that is formed on the outermost side, and an intermediate layer that is formed between the innermost layer and the outermost layer and has a gas barrier layer. This tubular container 1 is characterized by having a structure wherein all surfaces coming into contact with the content are formed from the non-stick resin or a structure with a transparent body part having a gas barrier layer.
Patent CA-2984264-A1 (CA)
Title: Nanovecteurs cibles pour une administration ciblee de medicament consistant en des agents de therapie genique
Inventor: FURCH MARCUS
IPC: A61K9/127
Filed: 2016-04-29
Abstract: La présente invention concerne des nanovecteurs ciblés - également appelés nanomédicaments - et des procédés destinés de préférence, ou activement, à cibler et à administrer un outil pour le transfert de gènes ou l'édition du génome (c'est-à-dire, un plasmide ou une enzyme de restriction - telle qu'une nucléase à doigts de zinc, un système CRISPR/Cas, ou un TALEN) ou un outil pour le silençage génique ou la régulation post-transcriptionnelle de l'expression génique (c'est-à-dire, un micro-ARN, un ARNsi, un ARNm, un oligonucléotide antisens ou un oligonucléotide sens) à un éventail d'espèces de cellules de mammifères. Un ciblage spécifique aux cellules est obtenu en utilisant des nanovecteurs caractérisés par des ancrages de ciblage appropriés comprenant une fraction de ciblage qui peut être un glucide, un anticorps ou un fragment d'anticorps, un dérivé de protéine non-anticorps, un aptamère, une lipoprotéine ou une fraction de celle-ci, un peptidoglycane, un lipopolysaccharide ou une fraction de celui-ci, ou un ADN CpG. De tels ancrages de ciblage peuvent comprendre, ou non, un espaceur polymère tel que le polyéthylène glycol. Les nanomédicaments permettront de cibler thérapeutiquement un éventail d'entités pathologiques de mammifères par l'intermédiaire de diverses voies d'application. Ces affections comprennent des maladies malignes, des maladies auto-immunes, des troubles héréditaires, des troubles métaboliques ou des maladies infectieuses.
Patent CA-2985918-A1 (CA)
Title: Methods and apparatus to align threaded fasteners
Inventor: GRAY EVERETTE DESMOND
IPC: G01B17/00
Filed: 2017-11-15
Abstract: Example methods and apparatus to align threaded fasteners are disclosed herein. An example apparatus includes a socket to hold a fastener and a sensor disposed adjacent the socket. The sensor is to measure acoustic waves near the socket while the socket rotates the threaded fastener in a reverse-thread direction against an end of a threaded pin. The example apparatus also includes an electronic control unit to determine whether the fastener and the threaded pin are aligned based on the acoustic waves measured by the sensor.
Patent CA-2986118-A1 (CA)
Inventor: ZOSKE MICK
IPC: A01C23/02
Filed: 2016-05-16
Abstract: In accordance with example embodiments, a hose mover and a system for moving a hose are provided.
Patent CA-2988119-A1 (CA)
Inventor: CANTOR HARVEY
IPC: A61K39/39
Filed: 2016-06-03
Abstract: Provided by the disclosure are methods for modulating differentiation of regulatory T cells (e.g., CD4+ or CD8+ regulatory T cells). In some embodiments, methods include contacting regulatory T cells with an agent that decreases Helios activity and/or Helios expression.
Patent CA-2988929-A1 (CA)
Inventor: YASHIN DMITRY
IPC: F16L37/02
Filed: 2017-12-13
Abstract: A coupling can include a coupling body having an axis, an axial length, an axial center, axial ends and an inner surface comprising an inner diameter that is substantially constant over an entirety of the axial length. A single shoulder can protrude radially inward relative to the axis from the inner surface, such that the inner surface has no other shoulders. In a version, the single shoulder is not axially aligned with the axial center of the coupling body.
Patent CA-2989534-A1 (CA)
Inventor: MIYAZAKI MASAKAZU
IPC: A61K47/26
Filed: 2016-07-01
Abstract: La présente invention concerne une composition pharmaceutique stable pour administration par voie orale contenant du 6-éthyl-3-({3-méthoxy-4-[4-(4-méthylpipérazine-1-yl)pipéridine-1-yl]phényl}amino)-5-(tétrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide (désigné composé A ci-après), ou un sel pharmacologiquement acceptable de celui-ci, qui supprime la génération de substances apparentées au cours du stockage. La proportion de cristaux du composé A ou du sel pharmacologiquement acceptable de celui-ci dans la composition pharmaceutique stable pour administration par voie orale est de 60 % ou plus par rapport au poids total du composé A ou du sel pharmacologiquement acceptable de celui-ci.
Patent CA-2990798-A1 (CA)
Title: Dispositif terminal, dispositif station de base, procede de communication et circuit integre
Inventor: SUZUKI SHOICHI
IPC: H04W16/28
Filed: 2016-07-01
Abstract: L'invention concerne un dispositif terminal qui décode un bloc de code d'un bloc de transport et, si un premier mode de transmission est réglé, alors l'adaptation de débit pour le bloc de code est traitée sur la base d'un premier nombre total de bits de canal souple ; si un second mode de transmission est réglé et des premières informations sont réglées, alors l'adaptation de débit pour le bloc de code est traitée sur la base du premier nombre total de bits de canal souple ; si le second mode de transmission est réglé et les premières informations ne sont pas réglées, alors l'adaptation de débit pour le bloc de code est traitée sur la base d'un second nombre total de bits de canal souple. Ici, les premières informations indiquent le nombre maximum de couches associé à une transmission en canal partagé de liaison descendante physique (PDSCH).
Patent CA-2994516-A1 (CA)
Title: Methode de traitement des troubles associes au fgf21
Inventor: YOWE DAVID LANGDON
IPC: A61K39/00
Filed: 2016-08-02
Abstract: La présente invention concerne des anticorps monoclonaux et des fragments de ceux-ci se liant à l'antigène qui se lient au ß-klotho humain, et des compositions pharmaceutiques et des méthodes de traitement les comprenant.
Patent CA-2994645-A1 (CA)
Inventor: NANRI TAKUYA
IPC: G08G1/16
Filed: 2015-08-04
Abstract: A step detection device detects, using a distance sensor 12 mounted on a vehicle Vc, the distance and direction to the road surface in the surroundings of the vehicle, and sets, on the road surface, a first step determination position Pa1 and a second step determination position Pa2. The step detection device then calculates, on the basis of the distance and direction to the road surface, the change in height of the road surface at the first step determination position Pa1 and the second step determination position Pa2, and detects a step LD on the road surface on the basis of the step determination position at which the change in height of the road surface has a large gradient.
Patent CA-2995196-A1 (CA)
Inventor: SHAH KUSHAL
IPC: C09K23/54
Filed: 2015-07-27
Abstract: The invention relates to the technical field of coated particles and methods for making coated powders. Embodiments include coated powders of TiO2 and other selected metal oxides, for use in UV protective topical skin compositions, and other UV  protective coatings, wherein the coated powders (a) are photostable, in that they do not significantly change color under exposure to UV light; (b) are not chemically reactive, in that they minimally react with, or discolor, compositions during storage; and (c) may be formed into high weight loading dispersions. Coated powder embodiments comprise (a) nanoparticles, and (b) a coating on the surface of the nanoparticles, including silica moieties, organo oxysilane moieties selected from the group consisting of mono-organo oxysilane moieties, bi-organo oxysilane moieties and tri-organo oxysilane moieties, and poly(dialkyl)siloxane moieties.
Patent CA-2998544-A1 (CA)
Title: Robotic systems and methods for identifying and processing a variety of objects
Inventor: WAGNER THOMAS
IPC: G05B19/418
Filed: 2016-09-09
Abstract: A robotic system is disclosed that include an articulated arm and a first perception system for inspecting an object, as well as a plurality of additional perception systems, each of which is arranged to be directed toward a common area in which an object may be positioned by the robotic arm such that a plurality of views within the common area may be obtained by the plurality of additional perception systems.
Patent CA-2999732-A1 (CA)
Inventor: ZHU JINGXU
IPC: C02F3/00
Filed: 2018-03-29
Abstract: The present disclosure discloses a slightly heavy particle system for wastewater treatment, comprising a contactor. Said contactor includes a gas-liquid-solid three-phase region, and said gas-liquid-solid three-phase region includes gas phase, liquid phase, and solid phase. Said liquid phase is the continuous phase and said solid phase is slightly heavy particles. Said slightly heavy particles are able to carry some microorganisms on their surfaces at least, and the density of said slightly heavy particles is higher than the density of said liquid. The slightly heavy particle system of the present disclosure applied in wastewater treatment can increase the concentration of microorganisms significantly, improve the ability to bear impact load, produce less sludge, and without sludge expansion. Meanwhile, the means to suspend slightly heavy particles with the combined effect of gas and liquid is able to reduce energy consumption to a larger extent. Therefore, this system features with high efficiency and low energy consumption.
Patent CA-3000156-A1 (CA)
Title: Device for measuring the parameters of phase elements and optical fiber dispersion and a method of measuring the parameters of phase elements and optical fiber dispersion
Inventor: STEPIEN KAROL
IPC: G01B11/06
Filed: 2015-11-30
Abstract: A device for measuring the parameters of phase elements and dispersion of optical fibers, characterized in that it contains: at least one light source, serially connected to at least one fiber optic coupler, one of whose arms constitutes a part of the reference arm, and whose second arm constitutes a part of the measurement arm of the device, and at least one motorized linear stage is mounted on at least one arm of the device, and at least one of the arms of the device is connected, either directly, or through an additional fiber optic coupler, to at least one detector, and at least one collimator is placed in at least of the arms of the device, at least before the phase element. A method of measuring the parameters of the phase element and the dispersion of optical fibers, applying the device according the invention, is conducted in at least two stages, wherein the first stage assumes the calibration of the device according to the invention, and the second stage is the proper measurement, characterized in that during calibration of the device according to the invention, light from the low-coherence light source (1.1) is directed to the fiber optic coupler (2.1), where it is separated into two arms: measuring and reference, and then the motorized linear stage(6) moves, recording information on its position until zero difference of optical paths between particular fiber optic coupler arms is obtained. Interference occurs in the fiber optic coupler(2.2), after passing through collimators (3.2) and (4.2), and interferogram is collected in time delay, which translates into motorized linear stage movement. Inteferogram is collected by a photodetector, in particular by a photodiode, and after the device is calibrated, the system proceeds to proper measurement, in which a phase element, particularly a lens intended for measurement, is inserted in the measurement arm of the device according to the invention, between the collimators (3.1) and (3.2), after which, sliding the motorized linear stage, the position producing zero optical path difference is determined, and the thickness of the phase element is determined on the basis of the differential position of the equivalent optical path in the calibration measurement and the proper measurement with the phase element, and basing on the knowledge of the refractive index of the glass the lens was made of.
Patent CA-3001708-A1 (CA)
Inventor: PIETRZAK CHRISTOPHER T
IPC: A42B3/00
Filed: 2016-10-24
Abstract: A helmet comprising an outer shell and a chin bar collar is disclosed. The outer shell comprises an interior surface and an open front portion. The chin bar collar comprises a chin guard and a collar segment forming a continuous loop. The collar segment is coupled to the interior surface of the outer shell. A majority of the collar segment is positioned within an interior space of the outer shell, and a majority of the chin guard is positioned outside the interior space of the outer shell. The outer shell may include at least two coupling points, at least one on each side of the open front portion, coupling the chin bar collar to the outer shell. The helmet may include at least one bracket coupled to the interior surface of the outer shell. The chin bar collar may be releasably coupled to the interior surface of the outer shell.
Patent CA-3002119-A1 (CA)
Title: Aqueous basecoat materials comprising crosslinked polyurethane binders and a specific solvent composition
Inventor: STEINMETZ BERNHARD
IPC: C08G18/76
Filed: 2016-10-31
Abstract: The present invention relates to a pigmented aqueous base paint containing an aqueous polyurethane-polyurea dispersion (PD) comprising polyurethane-polyurea particles which are contained in the dispersion and have an average particle size (volume average) of 40 to 2000 nm and a gel content of at least 50 wt.%. The polyurethane-polyurea particles each contain, in the reacted form, (Z1.1) at least one polyurethane prepolymer containing isocyanate groups and having anionic groups and/or groups which can be converted into anionic groups, and (Z.1.2) at least one polyamine containing two primary amino groups and one or two secondary amino groups, the aqueous base paint containing a special solvent composition. The present invention also relates to the use of base paints containing said dispersion (PD) and to multi-layer paints which were produced by using said base paints.
Patent CA-3002369-A1 (CA)
Title: Selection d'objets virtuels dans un espace tridimensionnel
Inventor: POWDERLY JAMES M
IPC: G06F1/14
Filed: 2016-10-18
Abstract: L'invention concerne des systèmes et des procédés permettant d'interagir avec des objets virtuels dans un espace tridimensionnel au moyen d'un système portable. Le système portable peut être programmé pour permettre à un utilisateur d'interagir avec des objets virtuels à l'aide d'un dispositif d'entrée utilisateur et de poses. Le système portable peut également déterminer automatiquement des informations contextuelles telles que la disposition des objets virtuels dans l'environnement de l'utilisateur et commuter le mode d'entrée utilisateur en fonction des informations contextuelles.
Patent CA-3003764-A1 (CA)
Inventor: GORDILLO ALVARO
IPC: C07D307/46
Filed: 2016-11-03
Abstract: The present invention relates to a process for preparing a mixture comprising 5-(hydroxy- methyl)furfural (HMF) and one or more HMF esters of formula (I, the process comprising the following steps: (A-1) preparing or providing a starting mixture comprising one, two or more carbohydrate compounds selected from the group consisting of hexoses, oligosaccharides comprising hexose units, and polysaccharides comprising hexose units, and as the solvent or as a co-solvent for said carbohydrate compounds an amount of one or more carboxylic acid esters of formula (II) (A-2) subjecting said starting mixture to reaction conditions so that at least one of said one, two or more carbohydrate compounds reacts, and a fraction of said amount of one or more carboxylic acid esters of formula (II) is hydrolyzed, so that a mixture results comprising 5-(hydroxymethyl)furfural and/or said one or more HMF esters of formula (I), one or more carboxylic acids of formula (III) and a remaining fraction of said amount of one or more carboxylic acid esters of formula (II) wherein the starting mixture prepared or provided in step (A-1) comprises a total amount of carboxylic acid esters of formula (II) of at least 50 wt.-%, based on the total weight of the starting mixture.
Patent CA-3004822-A1 (CA)
Inventor: HILFIKER ROLF
IPC: A61K31/5415
Filed: 2010-09-23
Abstract: On décrit trois formes B, C et D du dihydrate et une forme E du monohydrate de chlorure de méthylthioninium. Ces formes B, C, D et E peuvent être préparées dans des conditions dhumidité et de température contrôlées à partir dun chlorure de méthylthioninium de teneur en eau supérieure, ou par conversion dun hydrate. Ces hydrates peuvent être incorporés dans des compositions pharmaceutiques.
Patent CA-3005608-A1 (CA)
Inventor: DOMINOWSKI PAUL JOSEPH
IPC: A61K39/12
Filed: 2014-09-19
Abstract: The present disclosure provides adjuvant formulations comprising water-in-oil emulsions comprising immunostimulatory oligonucleotides. Use of the formulations for the preparation of immunogenic compositions and vaccines, and use thereof for the treatment or prevention of diseases is also provided.
Patent CA-3006141-A1 (CA)
Inventor: GAYDOS STEPHEN P
IPC: C25D3/20
Filed: 2018-05-23
Abstract: The present disclosure provides electrolyte solutions for electrodeposition of zinc-iron alloys, methods of forming electrolyte solutions, and methods of electrodepositing zinc-iron alloys. An electrolyte solution for electroplating can include an alkali metal citrate, an alkali metal acetate, a citric acid, and glycine with a metal salt. An electrolyte solution can be formed by dissolving an alkali metal citrate, an alkali metal acetate, a citric acid, and glycine in water or an aqueous solution.  Electrodepositing zinc-iron alloys on a substrate can include introducing a cathode and an anode into an electrolyte solution comprising an alkali metal citrate, an alkali metal acetate, a citric acid, and glycine. Electrodepositing can further include passing a current between the cathode and the anode through the electrolyte solution to deposit zinc and iron onto the cathode.
Patent CA-3006758-A1 (CA)
Inventor: HAGNER PATRICK
IPC: A61K31/517
Filed: 2016-12-01
Abstract: Provided herein are methods of treating, preventing and/or managing cancer, including lymphoma, which comprise administering to a patient 3-(5-amino-2-methyl-4- oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof, or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof in a cyclic therapy regimen.
Patent CA-3011472-A1 (CA)
Title: Therapeutic use of mitochondria and combined mitochondrial agents for transplantation
Inventor: MCCULLY JAMES D
IPC: A61P25/28
Filed: 2017-01-13
Abstract: The disclosure relates to compositions comprising isolated mitochondria or combined mitochondrial agents, and methods of treating disorders using such compositions.
Patent CA-3012260-A1 (CA)
Title: Luggage item with radio-tag reader
Inventor: MANNARELLI VALERIE
IPC: A45C13/18
Filed: 2017-01-23
Abstract: The invention relates to a luggage item (1) intended to contain removable objects (7, 8), the luggage item (1) comprising a casing (5) delimiting an internal space of the luggage item (1) able to contain the removable objects (7, 8), the casing (5) exhibiting an opening (6) forming a passage between the internal space of the luggage item (1) and an exterior environment of the luggage item (1), the luggage item furthermore comprising a radio-tag reader (2), the radio-tag reader (2) comprising: - an identification module (12) configured to emit by radiofrequency an identification request destined for a radio-tag (4) and to receive identification data from the radio-tag (4) in response to the identification request, - a communication module (13) configured to associate the radio-tag reader (2) with a remote device (3) by means of a wireless connection (17), the radio-tag reader (2) being configured to transmit the identification data received in response to the identification request to the remote device (3), - a power supply (14) able to energise components of the radio-tag reader.
Patent CA-3012425-A1 (CA)
Inventor: QUIRING CHRISTOPHE
IPC: C12Q1/04
Filed: 2017-01-25
Abstract: L'invention concerne des procédés, des compositions et des kits permettant d'analyser rapidement la croissance microbienne et/ou le nombre de micro-organismes dans une pluralité de gouttelettes d'émulsion eau dans l'huile.
Patent CA-3012782-A1 (CA)
Inventor: BAKER MICHAEL ARTHUR KEITH
IPC: A01K61/54
Filed: 2018-07-30
Abstract: A shellfish farm comprising a plurality of floats 1 at or near water level, a backbone rope 2, shock absorbing elastic cords 3 extending between the floats 1 and the backbone rope 2, and at least one shellfish growing rope 5 extending from the backbone rope 2 with shellfish attached.