baber/WOPTO huggingface dataset:
Patent PT-1891105-E (PT)
Title: Oxyntomodulin analogues and their effects on feeding behaviour
Inventor: BLOOM STEPHEN ROBERT
IPC: A61K38/26
Filed: 2006-06-13
Abstract: Compounds of the invention are novel peptide analogues of oxyntomodulin (oxm) in which one or more amino acids of the oxm sequence have been changed. Changing amino acids 15-24 of oxm to either amino acids 968 - 977 of the ±-latrotoxin peptide (and variations thereof) or amino acids 15 - 24 of exendin-4 (and variations thereof), or combinations of sequences from these sources, and/or changing amino acids 27-33 of oxm to amino acids 27-33 of exendin-4, and/or the addition of amino acids to the C-terminus of the peptide, results in a series of analogues of oxm that demonstrate the oxm like activity of reducing food intake, and with certain embodiments a greater ability to decrease food intake.
Patent PT-2014037-E (PT)
Title: Hover to call
Inventor: CHU LON-CHAN
IPC: H04M1/72445
Filed: 2007-04-17
Abstract: When the user hovers on a telephone number (or other indication of a target of a voice communication) on a web page (or other interface), the telephone number will be highlighted and the user will be provided with the opportunity to make a call using the highlighted number. If the user clicks on the highlighted telephone number, the telephone number will be provided to a communication application to facilitate making a telephone call. If the user moves away without clicking on the highlighted telephone number, the highlight will disappear. In alternative embodiments, a user can select text in a web page (or other interface) and, if there is a telephone number in the selected text, that telephone number can be automatically provided to the communication application to facilitate making a call. In another embodiment, the system finds telephone numbers in content and replaces those telephone number with hyperlinks to enable the behavior described above.
Patent PT-2153982-E (PT)
Title: Foamed plastic board
Inventor: WOLF THOMAS
IPC: B32B3/18
Filed: 2008-07-30
Abstract: The element has a foam block (5) made of foam plastic, and comprising a set of stacked foam bodies (7). The foam bodies are composed of body segments that are arranged in a plane next to each other, and are connected to each other. The body segments comprise weld seams (23) at abutting surfaces. The weld seams between the foam bodies are interrupted by recesses (45) that are provided at a distance from each other. An independent claim is also included for a method for manufacturing a flat structural element.
Patent PT-2090703-E (PT)
Title: Frame for holding a covering
Inventor: BLECHER JOERG
IPC: E03F5/06
Filed: 2009-01-28
Abstract: The frame (4) has an anchor-shaped element (10), by which the frame is fixed in a binding agent, particularly concrete. The anchor-shaped element is fixed at the frame. The anchor-shaped element is formed in a rod-shaped manner. The anchor-shaped element is formed from a round rod. The anchor-shaped element is made of steel. The anchor-shaped element is fixed by a retaining element (13) which is inserted in a recess of the frame. The retaining element is made of plastic.
Patent PT-2239253-E (PT)
Title: Novel phenylpyrrole derivative
Inventor: FURUKAWA AKIHIRO
IPC: A61K31/4439
Filed: 2009-02-04
Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having superior glucokinase activating activity, and is a compound represented by general formula (I), or pharmacologically acceptable salt thereof:   
[wherein,  A represents, for example, an oxygen atom or sulfur atom, R 1  represents, for example, a C 1 -C 6  alkyl group, a C 1 -C 6  alkoxy group or a C 1 -C 6  halogenated alkyl group, A and R 1  together with the carbon atom bonded thereto form a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ±, R 2  represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group ± or a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ±, R 3  represents a hydroxy group or a C 1 -C 6  alkoxy group, and Substituent Group ± consists of, for example, a halogen atom, a C 1 -C 6  alkyl group, a C 1 -C 6  alkyl group substituted with 1 or 2 hydroxy group(s), a C 1 -C 6  alkylsulfonyl group, and a group represented by the formula -V-NR 5 R 6  (wherein, V represents a carbonyl group or a sulfonyl group, and R 5  and R 6  may be the same or different and respectively represent a hydrogen atom or a C 1 -C 6  alkyl group, or R 5  and R 6  together with the nitrogen atom bonded thereto form a 4- to 6-membered saturated heterocycle that may be substituted with 1 or 2 group(s) independently selected from a C 1 -C 6  alkyl group and a hydroxy group, and the 4- to 6-membered saturated heterocycle may further contain one oxygen atom or nitrogen atom)].
Patent PT-2246417-E (PT)
Title: Recombinantly modified plasmin
Inventor: NOVOKHATNY VALERY
IPC: C12N15/57
Filed: 2005-04-21
Abstract: The present invention relates to a polynucleotide comprising a nucleotide sequence encoding a polypeptide having a single N-terminal kringle domain homologous to a kringle domain of native human plasminogen; and a C-terminal domain activation site and serine protease domain homologous to the corresponding domains in human plasminogen; wherein the polypeptide binds to immobilized lysine.
Patent PT-2381591-E (PT)
Title: Wireless terminal methods and apparatus for use in a wireless communications system that uses a multi-mode base station
Inventor: LAROIA RAJIV
IPC: H04W52/02
Filed: 2006-09-15
Abstract: A wireless terminal for communicating with a base station which supports a reduced synchronization signaling mode of operation and a full on synchronization mode of operation is described, the wireless terminal comprising: means for transmitting signals; means for determining if said base station is operating in said reduced synchronization signaling mode of operation; and means for controlling said means for transmitting to transmit a signal used to trigger the base station to transition into a more active synchronization signaling mode of operation when said means for determining that said base station is operating in said reduced synchronization mode of operation.
Patent PT-680356-E (PT)
Inventor: OKADA YOSUKE
IPC: A61M25/06
Filed: 1993-01-05
Abstract: A catheter introducer (31) which allows a dilator section (33) and a sheath section (32) to be engaged with and disengaged from each other promptly and smoothly. The catheter introducer (31) is composed of a sheath section (32) consisting of a sheath (35) and a sheath hub (34) and a dilator section (33) consisting of a dilator (38) and a dilator hub (36). The dilator hub (36) includes a flange (37) to cover the end of said sheath hub (34) in the state of engagement formed at the distal end of the dilator hub (36), a circular groove (40) formed in the internal circular portion of the flange (37) or in the external circular portion of the sheath hub (34), and a protrusion (39) to be engaged with said groove wherein the protrusion is formed on the external circular portion of the sheath hub or on the internal circular portion of the flange.
Patent PT-644929-E (PT)
Inventor: ERIKSSON ELOF
IPC: A61K35/36
Filed: 1993-06-11
Abstract: The invention provides use of exogenous genetic material in the manufacture of a medicament for use in a method of genetically engineering cells in vivo in a patient by injecting a solution containing the genetic material into skin cells with a microneedle.
Patent PT-717620-E (PT)
Inventor: SLEEVI MARK C
IPC: A61K31/341
Filed: 1994-08-05
Abstract: Optically active or racemic compounds represented by the formula   <IMAGE>   where R2 is OA and R3 is selected from the group consisting of H and OA; where A is H or is selected from the group consisting of hydrocarbyl radicals comprising between 1 and 3 carbon atoms, as well as   <IMAGE>   with the proviso that when R3 is OA, then R2 and R3 may be bonded together to form the group   <IMAGE>   R4 is selected from the group consisting of alkyl and aromatic residues having from 1 to 20, preferably from 1 to 12, carbon atoms, for example, alkyl, optionally substituted with aromatic residues, and aromatic residues optionally substituted with alkyl radicals; n is an integer from 1 to 4; R5 is an unbranched alkyl chain comprising from 1 and 3 carbon atoms or a cyclopropylmethyl radical; R1 is alkoxy, cycloalkoxy and a cyclic ether of the formula   <IMAGE>   where m is an integer from 3 to 5; with the proviso that when R1 is alkoxy, then R3 cannot be H; and pharmaceutically-acceptable salts thereof. These compounds are useful for alleviating Parkinsonism, glaucoma, hyperprolactinemia and for inducing weight loss in mammals.
Patent PT-726942-E (PT)
Inventor: SMET WALTER DE
IPC: C07K16/28
Filed: 1994-10-26
Abstract: The present invention relates to human foam cells generated in vitro from monocyte/macrophage related cell lines which give rise to an average intracellular cholesterol amount of at least 139 + 36  mu g/mg cell protein as determined by HPLC, with said cholesterol being characterized by a degree of 46+6% of esterification as determined by HPLC. The invention also relates to monoclonal antibodies selected via said foam cells and which can be used for pharmaceutical and diagnostic purposes.
Patent PT-807246-E (PT)
Inventor: KONIECZKA JOHN
IPC: G01M3/40
Filed: 1996-01-29
Abstract: The present invention relates to a method for testing for leaks in the bodies of sealed containers. The method comprises first placing a hole into the body of a sealed container, and then: (a) inserting a first electrode into a sealed container containing an electrolyte product composition, wherein the first electrode is inserted into the sealed container in a manner such that it is at least partially immersed in the electrolyte product composition; (b) immersing the sealed container into an electrolyte bath solution contained in a vessel, wherein the electrolyte bath solution is in direct contact with a second electrode, and wherein the sealed container is immersed into the electrolyte bath solution in a manner such that the seal of the sealed container is completely immersed in the electrolyte bath solution, the interior seal surface of the sealed container is completely submerged in the electrolyte product composition contained in the sealed container, and the first electrode is not in direct contact with the electrolyte bath solution; (c) connecting the first electrode and the second electrode to either a source of direct electric current or a conductivity measuring device; and (d) measuring the electric current flow or conductivity from one electrode to the other; wherein the sealed container is not leaking if there is no electric current flowing or electrical conductivity between the two electrodes, and the sealed container is leaking if there is electric current flowing or electrical conductivity between the two electrodes. The present invention further relates to an apparatus capable of detecting seal leaks in this manner.
Patent PT-827414-E (PT)
Inventor: FILAN FINBARR JOHN
IPC: A61M1/00
Filed: 1996-03-27
Abstract: The present invention is directed to a waste treating reservoir for treating waste collected using an associated suction system. A disposable receptacle connected to an associated suction system includes a sealed chamber such as a liner and a lid with a pour spout. The waste treating reservoir includes a closed container with an open mouth for storing a waste treating agent. A cylindrical wall forms a diffuser cap and has an open end portion and a substantially closed end portion. The closed end portion has a plurality of apertures opening radially through the cylindrical wall. The open end portion of the cylindrical diffuser cap fits telescopically over the open mouth of the agent container. The reservoir system further includes a double-walled sleeve having an inner wall and a generally concentric outer wall for attaching the combined diffuser cap and agent container to the spout of the disposable receptacle lid. The inside surface of the inner wall of the sleeve sealingly covers the radially opening apertures in the diffuser cap when the cap is in a first position relative to the sleeve. The outside surface of the inner wall and the outer wall are engagable with the cover spout of the receptacle so that the diffuser cap is slidable to a second position in the double-walled sleeve. At the second position, the radial opening apertures are moved axially beyond the inside surface of the inner wall of the sleeve. This allows an open passageway for the waste treating agent to flow from the interior of the agent reservoir to the chamber of the disposable receptacle. The waste treating reservoir of the present invention is configured so the system can be set up prior to the surgical procedure and can be readily activated immediately after the surgical procedure so that hazardous waste can be treated promptly and efficiently.
Patent PT-835110-E (PT)
Inventor: WHEELER LARRY A
IPC: A61K31/498
Filed: 1996-06-17
Abstract: A method according to which neuroprotection is conferred upon ocular nerve cells by administration of a drug of formula (I) to the optic nerve and/or retina of a mammal within a period prior to or following an insult to ocular nerve cells but prior to cell death, wherein the 2-imidazolin-2-ylamino group may be in either the 5- or 6-position of the quinoxaline nucleus; x, y and z may be in any of the remaining 5-, 6-, 7- or 8-positions and are selected from hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; and R is an optional substituent in either the 2-or 3-position of the quinoxaline nucleus and may be hydrogen, lower alkyl or lower alkoxy is disclosed.
Patent PT-1036464-E (PT)
Title: Method and apparatus for monitoring a patient
Inventor: VASKO ROBERT S
IPC: G06Q50/00
Filed: 1998-11-12
Abstract: A remotely programmable and accessible medical device system (10) including an interface unit (14) and a medical device (12) connected to a patient (18) is disclosed. Through a transceiver, such as a telephone (48) or computer (50), a person may obtain status reports from a remotely located medical device in audible, electronic or paper form. In addition, the person may change a protocol associated with the medical device or be alerted to a remote location of an alarm associated with the medical device.
Patent PT-1080476-E (PT)
Inventor: CLAUDIO VICENTELLI
IPC: G09B23/26
Filed: 1999-03-24
Abstract: Two cylindrical magnetic elements (2,3) are inserted in the slots (4,5), provided on the opposite bases of a cylindrical ferromagnetic yoke (6). The yoke containing magnetic elements is integrated in a nonmagnetic matrix (7). The polar surfaces (13,14) of the upper and lower magnetic elements are exposed for connecting with other modules.
Patent PT-1067933-E (PT)
Title: Semi-synthetic ecteinascidins
Inventor: RINEHART KENNETH L
IPC: A61K31/4995
Filed: 1999-04-05
Abstract: The present application is directed to several newly prepared semi-synthetic ecteinascidin (Et) species, designated herein as Boc-Et 729, Et 875, and Et 1560. The physical properties of these compounds, their preparation and bioactivities are also reported.
Patent PT-1082131-E (PT)
Inventor: KHAN NISAR AHMED
IPC: A61K38/24
Filed: 1999-05-20
Abstract: The invention relates to the field of immunology, more specifically to the field of immune-mediated disorders such as allergies, auto-immune disease, transplantation-related disease or inflammatory disease. The invention provides among others an immunoregulator (IR), use of an IR in preparing a pharmaceutical composition for treating an immune-mediated disorder, a pharmaceutical composition and a method for treating an immune-mediated disorder.
Patent PT-1152700-E (PT)
Title: Maneuverable fetal vacuum extractor for use with malpresenting fetus
Inventor: WALLACE WILLIAM DEAN
IPC: A61B17/30
Filed: 1999-11-30
Abstract: The fetal contact cup portion of a fetal vacuum cup has an inside surface which, when applied to a fetal head, defines a fetal contact chamber with the fetal head. One end of a tube is attached to the fetal contact cup such that vacuums within the tube are applied within the fetal contact cup. The other end of the tube can be connected with a vacuum source and with a handle. The tube has a very small average outside diameter compared with conventional fetal vacuum tubes. Thus the fetal vacuum cup is less intrusive during insertion and is more easily maneuverable, especially when the fetus is malpresenting in, for example, the high occipitoposterior or high occipitolateral positions. The average outside diameter of the tube may be, for example, less than 150 mils and has a finger grip that compression fits into a recess defined by the outer surface of the fetal contact cup for a lower profile and easy positioning of the fetal contact cup onto the flexion point of the fetal head. During traction, however, the finger grip pulls out of the recess for more efficient traction. The fetal contact cup may have a soft lip for contacting the fetal head. Furthermore, the tubing may have markings to indicate proper positioning of the fetal vacuum cup over the flexion point.
Patent SG-141794-G (SG)
Title: Process and apparatus for delivering preferably folded printing products to a further processing point
Inventor: LEU WILLY
IPC: B65H29/66
Filed: 1994-10-01
Abstract: By a first conveying device printing products are fed in an imbricated formation (S), in which each printing product rests on the following one, the fold edge of the folded products forming the trailing edge. The printing products are pushed into an intermediate stack from below. The respectively uppermost product of this intermediate stack is seized in the region of the fold edge by at least one sucker of a sucker arrangement, raised upward and brought into the conveying region (F) of a second conveying device. The latter has individually controllable grippers which are arranged at regular intervals, circulate along a closed path, seize the fold edges delivered by the sucker arrangement and convey away the printing products thus seized. By forming an intermediate stack, from which the printing products are then raised by the sucker arrangement at the desired rate and fed to the grippers, even imbricated formations (S) occurring with irregularities can be processed satisfactorily.
Patent IE-38903-L (IE)
Title: Explosive slurry composition
IPC: C06B47/14
Filed: 1974-02-19
Abstract: An explosive slurry composition having excellent suspension stability, good thixotropic characteristics, high detonation power and good temperature characteristics comprises as ingredients a water-swollen gel of a complex composed of sodium montmorillonite and a water-soluble organic compound having a polar group, and an oxygen supplier such as ammonium nitrate and/or a sensitizer such as aluminum powder and/or a fuel such as saccharide, fuel oil and the like. This explosive slurry composition is used for blasting hard rocks and the like in situ connected with a booster or cap.
[US3956040A]
Patent IE-780368-L (IE)
Title: Reassembled meat products
IPC: A23L13/00
Filed: 1978-02-21
Abstract: A process for binding pieces of cooked meat together to produce a unitary product by impregnating pieces of uncooked meat with an aqueous solution containing a source of phosphate ions, cooking the meat, coating the cooked meat with an edible, heat-settable, thermostable glue containing an emulsifier selected from the group consisting of mono-diglycerides derived from stearic acid and sodium stearoyl-2-lactylate, compacting the coated pieces of meat and heating the compacted pieces of meat to obtain a product which on reheating remains cohesive.
[US4264633A]
Patent IE-34084-L (IE)
Title: Energetic constituent for explosives
IPC: C06B47/14
Filed: 1970-04-03
Abstract: 1,229,736. Incendiary and explosive compositions. IMPERIAL CHEMICAL INDUSTRIES Ltd. 1 April, 1970 [25 April, 1969], No. 21313/69. Heading C1D. An energetic constituent for incendiary or explosive compositions comprises liquid non- explosive organic nitrate thickened with nitrocellulose and ethyl or methyl centralite (diethyl or dimethyl diphenylurea). Liquid nitrates specified are n-propyl nitrate, iso-propyl nitrate, and amyl nitrate. The energetic constituent may form part of an extrudable blasting explosive, an aqueous slurry epxlosive, or a powdered explosive. Other ingredients of the explosive compositions are ammonium nitrate, sodium nitrate, water, granular aluminium, guar gum, and zinc chromate.
[GB1229736A]
Patent IE-36270-L (IE)
Title: Substituted quinolines.
IPC: A61K31/47
Filed: 1972-04-10
Abstract: 1387595 Derivatives of 4-aminoquinoline ROUSSEL UCLAF 10 April 1972 [8 April 1971] 16489/72 Heading C2C [Also in Division A5] The invention comprises compounds of formula and their non-toxic acid addition salts, wherein R 1 is H, F, Cl, Br, I, CF 3 , CN, NO 2 or C 1-8 alkyl, alkoxy, alkylthio, alkylsulphonyloxy, alkylamino or acylamino; R 2 is H, Cl or Me; Y is a thiophene or thiazole residue to which the amino and carboxylic group are attached in adjacent positions, which residue is optionally further substituted by C 1-6 alkyl; and X is H, C 1-6 alkyl, Ph, di(C 1-6 alkyl)amino-C 1-6 -alkyl (or a quaternary C 1-6 alkyl halide thereof), morpholinoalkyl, glyceryl (or a cyclic ketal thereof with Z 2 CO where Z is C 1-5 alkyl) or 2-Y- 1,3-dioxan-5-yl where Y is C 1-6 alkyl or monocyclic aryl. In examples, these compounds are prepared by (1) reacting a 4-chloroquinoline with NH 2 -[Y]-CO 2 X, (2) hydrolysing the above esters to obtain the acids, (3) transesterification, or (4) hydrolysing esters of 2,2-dimethyl-1,3- dioxolan-4-ylmethanol to the corresponding glycerol esters.
[GB1387595A]
Patent IE-36710-L (IE)
Title: Hydrazinopyridazine derivatives
IPC: C07D207/06
Filed: 1972-05-09
Abstract: Pharmaceutical compositions comprising as the active ingredient thereof an aminopyridazine derivative of the formula: <IMAGE> wherein R1 is amino, or <IMAGE> wherein each of R3 and R4 is alkyl of 1 to 4 carbon atoms, or R3 and R4 together with the carbon atom to which they are bound, form a cycloalkylidene radical of 5 to 12 carbon atoms, R2 is hydrogen or methyl, A is -(CH2)n-, wherein n is 0 or an integer from 1 to 7, or >N-CO-R5, wherein R5 is alkyl of 1 to 16 carbon atoms, alkenyl of 3 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, 1-adamantyl, or -(CH2)m-R6, wherein m is 0 or an integer from 1 to 4, and R6 is phenyl; phenyl monosubstituted by fluorine, chlorine, bromine, alkyl or alkoxy of 1 to 4 carbon atoms, alkylmercapto of 1 to 4 carbon atoms, or phenyl; phenyl substituted by two or three substitutents of the group chlorine, alkyl or alkoxy of 1 to 4 carbon atoms; diphenylmethyl, the phenyl rings of which may be monosubstituted by fluorine, chlorine, bromine, alkyl or alkoxy of 1 to 4 carbon atoms; or naphthyl, or -OR7, wherein R7 is alkyl of 1 to 4 carbon atoms, or alkenyl of 2 to 4 carbon atoms or phenyl or phenalkyl, which may be monosubstituted on the phenyl ring by chlorine, alkyl or alkoxy of 1 to 4 carbon atoms, and in which the alkylene chain of phenylalkyl is of 1 to 4 carbon atoms, R8 and R9 are each hydrogen or alkyl of 1 to 4 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof are useful in the treatment of hypertension.
[US3838125A]
Patent IE-44729-L (IE)
Title: Identity card
IPC: B42D25/405
Filed: 1977-03-25
Abstract: An identification card with a holographic security safeguard in the form of a large area Lippmann-Bragg hologram recorded on a layer or sheet-like carrier disposed on a face of the identification card, capable of being read out without the use of laser light, employing merely normal light sources which produce incoherent light, whereby an image can be observed with the naked eye, and which can contain both binary and analog information, comparable, for example, with printed and other information contained on the identification card; and a method of producing such a card.
[US4171766A]