baber/WOPTO huggingface dataset:
Patent EC-SP982439-A (EC)
Title: Derivados de benzoxazindiona, aplicación de los mismos y medicamentos que los contienen
Inventor: HEINISCH LOTHAR
IPC: C07D205/08
Filed: 1998-03-04
Abstract: La invención se refiere a novedosos derivados de benzoxazindiona de la fórmula general I, y sus conjugados con sustancia activa, por ejemplo antibióticos. Los compuestos de la presente invención constituyen derivados heterocíclicos protegidos de catecol y son eficaces como sideróforos frente a cepas bacterianas gram negativas, particularmente Pseudomonáceas, cepas E.coli y Salmonella. Los mismos en forma de us conjugados con sustancia activas, por ejemplo antibióticos (conjugados antibióticos sideróforos) pueden introducir estos antibióticos en la célula bacteriana y aumentar o ampliar su eficacia antibacteriana en parte también frente a otras cepas bacterianas resistentes a otras B-lactamas. Además dichos compuestos son adecuados como formas premedicamentosas potenciales como quelatantes del hierro para la utilización en afecciones causadas por perturbaciones de metabolismo del hierro. La aplicación de la invención puede tener lugar en investigación farmacéutica, industria y agricultura. Fórmula I (gráfico), en donde R1 representa H o carboxialquilo, R2 representa H, alquilo o fenilo y R3 representa diversos grupos ácidos derivados de aminoácidos, depéptidos e hidrazonas o sus conjugados con sustancias activas, por ejemplo antibióticos. Dichos compuestos pueden existir en forma de ácidos libres, de sus sales o como ésteres fácilmente desdoblables.
Patent FI-20031464-A (FI)
Inventor: POSS MICHAEL A
IPC: C07D307/54
Filed: 2003-10-07
Abstract: Novel methods for the preparation of sidechain-bearing taxanes, comprising the preparation of an oxazoline compound, coupling the oxazoline compound with a taxane having a hydroxyl group directly bonded at C-13 thereof to form an oxazoline sidechain-bearing taxane, and opening the oxazoline ring of the oxazoline sidechain-bearing taxane so formed. Novel compounds prepared by the methods of the present invention are also provided.
Patent FR-1601228-A (FR)
Title: Prefabricated heat and sound-insulating - walls and partitions for buildings
IPC: E04C2/04
Filed: 1968-12-23
Granted: 1970-08-10
Abstract: Hollow brickwork is incorporated in a light material such as agglomerated pumice grit or plastics, pref. polystyrene, between 2 layers of reinforced concrete. Preferably full panels, or panels with openings, are made in jointed profiled moulds. A 3rd layer of reinforced concrete can have a reinforcing grid connected to the others, with a plate of heat-insulator e.g. expanded polystyrene, in its thickness.
Patent GB-1050856-A (GB)
IPC: F41H5/02
Abstract: 1,050,856. Armour plating. ALUMINIUM LABORATORIES Ltd. June 21, 1965 [July 8, 1964], No. 28231/64. Heading F3X. An armour plate, e.g. of aluminium alloy, has a series of parallel serrations on one face thereof, the serrations preferably having an apex angle in the range of 80 to 120 degrees. The serrations may extend to a depth of 20% to 40% of the thickness of the plate and be at about ¥ inch intervals. The plate is from 0À75 to 4 inches in thickness and contains by weight approximately 4À5% magnesium, 0À75% manganese 90À12% chromium.
Patent GB-1051229-A (GB)
IPC: F16D69/04
Abstract: 1,051,229. Disc brakes. SOC. ANON FRANCAISE DU FERODO. June 14, 1965 [June 15, 1964], No. 25101/65. Heading F2E. In an hydraulically actuated floating caliper disc brake particularly suitable for motor vehicles at least one of two pads 13, 14 is associated with a sloping face 22 which co-operates with a repartition device shown as a roller 23 which is in abutment with a fixed support 27 and with a face 28, parallel to the disc, on the caliper 15. As shown for a disc brake in which the disc 10 has a forward direction of rotation F the sloping face is on an element 21 which is in sliding contact with a piston 19 of an hydraulic actuation 18 and with one pad 13. Friction between the pad 13 and the element 21 may be increased by grooving or roughening the surfaces. A pair of tension springs 29 tend to move the pad 13 downwards against a fixed stop (not shown) and the element upwards until it contacts the roller 23 moving the pad towards the disc to take up wear. When the brake is applied the piston exerts a force in the direction of arrow A engaging the brake and causing an upward force to be exerted on the pad 13. This force is transferred to the element 21 and the roller 23 which exerts a force in the direction of arrow D tending to tighten the brake. The friction between the pad 13 and the element 21 may be chosen so that no slipping occurs during braking or so that the pad slips until it abuts a fixed stop 30.
Patent GB-1052976-A (GB)
IPC: C07B45/02
Abstract: 1,052,976. Neutralizing raw detergents. MARCHON PRODUCTS Ltd. Aug. 11, 1965 [Aug. 27, 1964], No. 35125/64. Heading C2C. A process for the continuous neutralization of sulphated or sulphonated detergent raw materials comprises reacting the said materials with an alkali in a mixer, which mixer comprises: a hollow stator member having an internal surface provided with a helical thread and enclosing a co-operating rotor member which is provided with an external helical thread of opposite hand to that on the stator member and not intermeshing therewith, the envelopes of the crowns of the helical threads defining two frusto-conical surfaces having a clearance between them and the depths of the threads varying in opposite senses between a maximum at one end and a minimum at the other end; said stator member being provided with an inlet for reactants at the basal portion of the frusto-conical surfaces, an outlet for the reaction products at the narrow end of the frustoconical surfaces, and means for rotating the rotor relatively to the stator about their common axis. In a preferred embodiment the pitch of the rotor thread is 50% greater than that on the stator, and the minimum pitch depth is zero. The preferred alkalis are NaOH, Na 2 CO 3  or KOH, used between 40-90‹ C., to neutralize sulphonated alkaryl hydrocarbons to which a small quantity of water has been added to stabilize the sulphonated hydrocarbon. The said raw materials are preferably derived by the process of Specifications 969,516 and 969,517. Especially suitable mixers are described in Specifications 842,692 and 882,517.
Patent GB-1053405-A (GB)
IPC: G01S1/02
Abstract: 1,053,405. Aerials; radar. ASSOCIATED ELECTRICAL INDUSTRIES Ltd. April 6, 1965 [April 24, 1964], No. 17072/64. Headings H4A and H4D. In a microwave transmitter having a linear aerial array of the kind in which the radiated beam is made to sweep recurrently through an angle by varying the frequency, and in which the generation of a marker pulse for a display is required when the radiated beam axis is pointing in a predetermined fixed direction, said marker pulse is triggered by the resonance of a cavity which is adjacent to the array and which is coupled to its feeder waveguide. It is stated that compensation for the effects of thermal expansions and contractions of the array is provided by equivalent changes of the dimensions of the resonant cavity. As described the array comprises a waveguide WG, Figs. 2, 3 (not shown), with radiating slots a, b on its upper face. A cylindrical cavity RC, Fig. 6 (not shown), made of material having the same coefficient of thermal expansion as the waveguide WG is coupled to it by slot S near the array slots a, b. A tuning plunger adjusts the frequency of resonance of the cavity RC and a probe P at an antinode is connected to a trigger circuit for a bearing marker generator which may, for example, cause a line BM, Fig. 1 (not shown), to appear on the B scan display of a radar equipment. More than one cavity may be used, each being tuned to a different frequency and causing the generation of a different bearing marker.
Patent GB-1053518-A (GB)
IPC: D01H13/16
Abstract: 1,053,518. Lamps. E. BREUNING. June 18, 1964 [June 20, 1963], No. 25201/64. Heading F4R. [Also in Division D1] In a monotoring device, particularly for detecting the temporary or other appearance of " foreign bodies " especially those of small dimension on one direction such as threads, ribbons and wires, comprises a source of radiant energy with a diffusely-radiating surface and a receiver with their axes aligned to define a monotoring beam, while, to eliminate the effect on the receiver of exterior interfering radiating sources, a plurality of shutter elements are spaced along the beam and have pervious apertures symmetrical to the axis of, and having a dimension exceeding the cross-sectional dimension of, the beam. In Fig. 1. not shown, a light source 1 produces a cone of light 2 of which the central portion 3 provides a beam picked up by a receiver 4 which is shrouded at 5. Apertured shutters 7-10 protect the receiver from extraneous lights 15, 16. The area of the surfaces of the source and receiver equals that of the body 17 to be detected. The apertures in the shutters may be of a size to allow for vibration of the source, receiver and shutters derived from the machine on which they are used. The shutter 8 is so arranged relatively to the shutter 7 to restrict the cone within which light entering the shutter 7 may reach the receiver and additional restriction to make the device sensitive over a long distance may be achieved by suitably positioning the other shutters. The source, receiver and shutters may be adjustable. The source may emit infra-red or ultra violet radiation, a colour of the spectrum, or modulated radiation from a gaseous discharge tube, or radiation from an incandescent body of high thermal inertia; in the latter case an incandescent body or filament may be energized by direct current and the receiver followed by an amplifier responsive only to the fluctuations of the received radiation. The shutters may be retractable (Fig. 3, not shown), and coated to minimize reflection of light, while they may be of equal sizes. Extraneous lights may be fitted with filters. The response of the receiver may operate a signal or operate a control.
Patent GB-1054691-A (GB)
IPC: C23F11/18
Abstract: 1,054,691. Non-corrosive waters. NALCO CHEMICAL CO. May 19, 1964 [July 9, 1963], No. 20576/64. Heading B1J. A process for maintaining a non-corrosive environment in industrial waters, e.g. boiler waters, in which the dissolved chromates do not exceed 1000 parts/million comprises adjustment of pH to 6.5 or less, ion exchange with a strong base exchanger in the mineral acid radical form, regeneration of the exchange with mineral acid/salt solution with a pH of at least 8.5 and return of the chromate from the regeneration to the system.
Patent GB-1054735-A (GB)
IPC: C08G63/54
Abstract: 1,054,735. Polyester resins. CHEMISCHE WERKE ALBERT. March 31, 1965 [April 4, 19641, No. 13664/65. Addition to 993,378. Heading C3P. A heat curable moulding composition comprises a crystallizable unsaturated polyester having an acid value below 50, the acid component of which consists of from 40 to 80 mol. per cent of maleic units and from 60 to 20 mol. per cent of terephthalic units and the alcoholic component of which is derived from dihydric alcohols at least 30 mol. per cent of which have two hydroxy groups of equal reactivity and also a symmetrical molecule, a vinyl monomer, a filler or fibrous material or both, a polymerization catalyst active at elevated temperatures and a lubricating agent. In the examples, the polyesters are formed from maleic anhydride and terephthalic acid (with or without adipic acid) and (1) and (2) ethylene glycol, (3) equal parts of ethylene glycol and propane-diol-1,2, and (4) 60 mol. per cent propane-diol-1,2 and 40 mol. per cent ethylene glycol, diallyl phthalate being the comonomer in each case; the lubricant is zinc stearate and some or all of the following fillers and fibres are added: limestone, kaolin and glass fibres.
Patent GB-1084035-A (GB)
IPC: H01J3/02
Abstract: 1,084,035. Electron guns. VARIAN ASSOCIATES. Nov. 26, 1964, No. 48146/64. Heading H1D. An electron gun, e.g. for a klystron, comprises an indirectly heated cathode 26 and a focusing electrode 27 mounted upon a hollow dielectric support shell 14, 16, the dielectric shell being supported and accurately positioned within a hollow metallic housing portion 2 by positioning structures 79, 61, structure 61 forming a hermetic seal between the housing and the shell. The cathode 26 is supported by a plurality of ribbed supports 37 circumferentially spaced around the cathode periphery and terminating in a groove 114 (Fig. 2, not shown) provided on the cylindrical outer surface of the cathode. Heat shields 29 serve to reflect back radiated heat to the cathode.
Patent GB-1230486-A (GB)
IPC: B44F1/14
Filed: 1968-08-19
Abstract: 1,230,486. Ornamenting. E. BISHOP, and E. PHINNEY. 19 Aug., 1968 [21 Aug., 1937], No. 39549/68. Heading B6G. Ornamental objects are decorated by dipping into a reservoir of liquid resin, and dipping the resin coated object prior to setting of the resin into a supply of crystals whereby the coating of resin will adhere crystals to the object, allowing the object to dry thereby setting and hardening the resin and securing the crystals in place on the object, coating the object with a second layer of resin, sprinkling crystals on to the second resin layer prior to setting and hardening, and drying the second resin layer. The ornamental object may be a plastics flower, or artificial tree. The crystals may be polystyrene crystals and the resin employed may be transparent. An iridescent effect is said to be produced on the surface of the object.
Patent GB-1230741-A (GB)
IPC: A63H3/40
Filed: 1969-01-31
Abstract: 1,230,741. Reading doll. MATTEL, Inc. 31 Jan., 1969 [12 Feb., 1968], No. 5365/69. Heading A6S. [Also in Divisions G4 and G6] A figure toy has movable eyes with eye moving means for moving the eyes at a first rate in one direction and at a second slower rate in the reverse direction so that the eyes move through simulated reading patterns. Additionally, the toy is provided with movable arms and a sound producing device, the two being attached, so that when the arms are moved to a first position the sound producing device produces a first character of sound corresponding to non-reading sounds, and when the arms are moved to a second position the sound producing device produces a second character of sound corresponding to reading sounds. The eye drive structure is shown in Fig. 9 wherein the eyeballs 20 and 22 are mounted in transparent bubbles 24 and 26 which in turn are mounted in eye sockets 28 and 30 within head 12 of the toy. Cross link 36 is a unitary structure with pins 38 and 40 which engage on the back of the eyeballs. Thin sections 42 and 44 act as hinges to permit relative bending movement of the link with respect to the eyeball. Guide bar 46 is positioned under link 36 and a similar guide bar can be placed over it and so the eyeballs will rotate upon their own vertical axis. The eye moving mechanism is operated by means of a pulley 54 carried on a worm shaft 48 (not shown) which also carries worm 58 which is in gear tooth engagement with gear 60 (Fig. 9). Gear 60 is pivoted on pin 62, which is secured inside the head 12, and engages gear 64, which carries crank pin 68 extending forward from its face. Yoke 70 is pivoted on pivot 72 and has a slot 74 which engages upon crank pin 68. Connector pin 76 extends forward from the yoke adjacent to pivot 72 and engages in cross link 36. As the pulley is rotated, gear 64 rotates in a clockwise direction. This causes angular oscillating motion of link 70 about its pivot pin 72 with yoke 70 moving more slowly while crank pin 68 is farther away from pin 72 and returning relatively fast in anti-clockwise direction as pin 68 is close to pin 72. This causes the eyes to sweep slowly in the reading direction and return rapidly in the opposite direction.
Patent GB-1231023-A (GB)
IPC: C08F8/12
Filed: 1968-11-20
Abstract: 1,231,023. Alcoholizing olefin - vinyl ester copolymers. E.I. DU PONT DE NEMOURS & CO. 20 Nov., 1968 [20 Nov., 1967], No. 55137/68. Heading C3P. Olefin - vinyl ester copolymers, in particular ethylene - vinyl acetate copolymers, are alcoholized by suspending the copolymer pellets in a reaction medium comprising an aliphatic alcohol containing 1 to 4 carbon atoms such as methanol and an alcoholizing catalyst, and maintaining the temperature of the medium above 35‹ C. and below the temperature at which the pellets dissolve or block. Suitable catalysts are sodium methoxide and hydroxide, and the corresponding potassium compounds. The alcoholization of ethylene - vinylacetate copolymer pellets, in methanol - sodium methoxide, is exemplified.
Patent GB-1231293-A (GB)
IPC: A44C7/00
Filed: 1969-08-20
Abstract: 1,231,293. Earclip. A. R. SACCOCCIO. 20 Aug., 1969, No. 41460/69. Heading A3H. An earclip comprises a pair of pivotally connected members 16 and 12 each of which has a portion adapted to engage opposite sides of a wearer's ear lobe 52, wherein one of said members has a pair of substantially parallel lugs 22 and means, e.g. the shaft 14, non rotatably carried by said lugs and the other of said members has a rolled portion 36 extending around said means, the rolled portion and the aforesaid means having dimensions such that a frictional drag exists between them which serves to maintain the members in any desired position relative to each other. The rolled portion 36 and the shaft 14 are substantially circular in cross-section and each have corresponding flat sections 38 and 28 whereby the rolled portion is freely slideable on to said shaft when the flat sections are aligned. The rolled portion 36 consists of a partially open loop whereby some degree of resiliency exists between the rolled portion and the shaft. The shaft is non rotatably held in the lugs by means of pintles 30, 32, one of which is non circular, which engage in openings 24, 26 in the lugs. The two members are of metallic construction, one member being formed from a harder metal than the other. In an embodiment the means non- rotatably carried by the lugs comprises two pintles integral with the lugs, the pintles terminating in spaced relation with respect to each other and having flat sections corresponding to those of the rolled portion. In a further embodiment the means non rotatably carried by the lugs comprises a shaft of circular crosssection, the rolled portion co-operating with this shaft also being of circular cross-section and having a diameter slightly less than that of the shaft. A stop (44), Fig. 11 (not shown), may be fitted to the member 12 to limit the pivotal movement of the other member 16.
Patent GB-1238701-A (GB)
IPC: B41N3/03
Filed: 1968-09-25
Abstract: 1,238,701. Planographic printing plates. KALLE A.G. 25 Sept., 1968 [28 Sept., 1967], No. 45563/68. Headings B6C. [Also in Divisions C7 and H5] A metal, e.g. steel or aluminium, foil 3 for use as a planographic printing plate is cleaned and roughened by a plasma jet 5. The jet may contain oxygen or kieselguhr to form an oxide or silicate surface, and the surface may be coated with copper, titanium or silicon carbide by introducing powdered material into the jet. The foil may be supported by coolant, which may be conductive, in a container 6. The jet may be moved transversely of the foil.
Patent GB-1250954-A (GB)
IPC: H01H1/50
Filed: 1969-02-07
Abstract: 1,250,954. Switchgear structures; vacuum switches. WESTINGHOUSE ELECTRIC CORP. 7 Feb., 1969 [28 Feb., 1968], No. 6753/69. Heading H1N. In a truck mounted multipole circuit interrupter a plurality of vacuum switches 2, 3, 4 are mounted on a wheeled truck by flexible mounting means including resilient conducting straps 20, 21, 30 connected between the ends of the switches and the spaced, horizontally disposed, terminal bushings 25, 27. The straps 20, 21 for each switch are connected on either side of a large contact block 18 connected to one of the switch contact rods 16, this block acting as a heat sink. Each switch is operated by means of an insulating rod 42 engaging a pivoted lever 38. A lost motion connection exists between the rod and the top 38a of the lever. In Fig. 4 a movable metal weight 81 is threaded on to the upper end of the stationary contact rod 16 and is caused by the impact of the closing operation to move up its guide 86 thus absorbing kinetic energy and preventing contact bounce. The weight 81, which preferably corresponds with the effective weight of contact 15, may be movable within a fluid-filled, e.g. air, dashpot, Fig. 10 (not shown).
Patent GB-1252523-A (GB)
IPC: C13K1/10
Filed: 1969-03-31
Abstract: 1,252,523. #-Glucose. TOKAI TOGYO CO. Ltd. 31 March, 1969 [6 April, 1968], No. 16685/69. Heading C2C. Crystalline anhydrous #-glucose is obtained by concentrating an aqueous solution containing glucose under a reduced pressure to a concentration of Brix 88‹-91‹ (x Brix‹ means x% by weight of solid in solution at 20‹ C.), seeding the concentrated solution with crystalline anhydrous #-glucose at (a) 85-110‹ C. using a shock seeding method or (b) 80-110‹ C. using a full seeding method, and subjecting the resulting mixture to crystal growth at 70-110‹ C., and recovering the crystals formed.
Patent GB-1257377-A (GB)
IPC: A01N25/08
Filed: 1969-05-29
Abstract: 1,257,377. Solid pesticidal composition containing DDVP. SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ N.V. 29 May, 1969, No. 27326/69. Heading A5E. A solid pesticidal composition which releases gaseous dichlorvos (DDVP) to the atmosphere comprises 1) DDVP, 2) an organic solid of m.p. 40‹C to 250‹C and which may sublimate at room temperature, and 3) a thermoplastic polymeric material. Many components 2) and 3) are listed and those preferred are:- 2) pdichlorobenzene, #-naphthol, biphenyl, naphthalene and tricyclodecane; 3) polyvinyl chloride, polymethyl methacrylate and polystyrene. The solid compositions may be in the form of rods or cubics, and also disclosed is a special holder for a shaped composition of the invention such that falling off in release of dichlorvos (DDVP) is reduced.
Patent GB-1259282-A (GB)
IPC: D06P1/00
Filed: 1968-04-17
Abstract: 1,259,282. Dyeing with polymerizable azo dyes. IMPERIAL CHEMICAL INDUSTRIES Ltd. 16 April, 1969 [17 April, 1968], No. 18115/68. Heading C3G. [Also in Division D1] Polymeric materials e.g. cellulose acetate, polyurethane, polyamides, optionally modified polyacrylonitrile, aromatic polyesters are dyed by applying in either order or simultaneously a polymerization initiator and a suspension or solution of an azo dyestuff free from sulphuric acid groups and containing a group of formula -N[Y n -X] 2  in which each Y is an optionally substituted alkylene group, each n is 0 or 1 and each X is of formula in which R 1 , R 2  and R 3  each independently represent hydrogen or a methyl group. The materials may be dyed in presence of monomers other than the dyestuff and optionally in presence of a conventional carrier. The group -N[Y n -X] 2  is preferably attached in a para position of an aryl nucleus to the azo group. Polymerization initiators include hydrogen peroxide, persulphates and 1,1 azobis-1-cyanocyclohexane. Reference has been directed by the Comptroller to Specification 1,046,751.
Patent GB-1267136-A (GB)
IPC: A61K39/12
Filed: 1970-06-30
Abstract: 1,267,136. Culturing tissue cells. INSTITUT PASTEUR. June 30, 1970 [July 9, 1969], No.31514/70. Heading C6F. A method of culturing tissue cells of the type which grow in a monolayer film, involves fixing the tissue cells on porous silica spherules of size between 125 and 150 microns and maintaining the spherules in suspension in the culture medium. Between 1 and 10 grams of spherules are used for each litre of culture medium. The cultured cells are recovered by rapid trypsinization after allowing them to settle. An example relates to the cultivation of mouse thymus cells infected with leukemia virus.