baber/WOPTO huggingface dataset:
Patent CA-3099335-A1 (CA)
Inventor: BURGESS JOSHUA T
IPC: A61K31/166
Filed: 2018-12-21
Abstract: L'invention concerne des procédés de traitement d'un cancer avec ou de prédiction de la réactivité d'un cancer à un agent anticancéreux qui est capable d'inhiber une enzyme qui induit la réparation de cassures de brin d'ADN, tel que la PARP, ledit procédé comprenant l'étape de détermination d'un niveau d'expression de SASH1. L'invention concerne également un procédé de traitement d'un cancer qui comprend l'administration d'une quantité thérapeutiquement efficace d'un agent qui augmente l'expression et/ou une activité de SASH1. L'invention concerne en outre des procédés d'identification d'un agent qui module l'expression et/ou une activité de SASH1 pour une utilisation dans le traitement du cancer.
Patent CA-3099982-A1 (CA)
Inventor: WASSERMAN ROBERT
IPC: G06Q30/02
Filed: 2019-05-17
Abstract: Electronic display systems, including roadside display devices, vehicle-based devices, personal mobile devices, advertising servers and/or networks, and/or additional external data sources may operate individually or in combination to identify vehicle locations, driving routes, driver and passenger characteristics, driving behavior and patterns, telematics data, and the like. Vehicle and individual characteristics and/or telematics data may be determined based on data received from traffic cameras, vehicle-based devices, personal mobile devices, telematics devices, software applications, etc. Based on the vehicle characteristics, individual characteristics, and telematics data, content, such as digital display or audio content, may be determined for output on various devices, such as electronic roadside displays to be viewable by the approaching vehicles, or other devices to be accessible by associated individuals. Various techniques may be used to determine customized content. Additionally, certain systems may be interactive to allow user responses and follow-up content via on-board vehicle or user devices.
Patent CA-3101752-A1 (CA)
Title: Destruction des graines de mauvaises herbes avec entrainement mecanique
Inventor: MAYERIE DEAN
IPC: A01F12/42
Filed: 2016-07-13
Abstract: Les graines de mauvaises herbes sont détruites dans la paillette dune moissonneuse-batteuse par des impacts à haute vitesse répétitifs causés par un rotor monté sur lun des deux boîtiers côte à côte. Le rotor fait accélérer les graines jetées dans une direction centrifuge qui lui est opposée sur un stator qui comprend des surfaces de stator à angle ajustable disposées autour de laxe. Les graines jetées rebondissent ainsi entre le rotor et le stator et subissent plusieurs impacts. Les graines sont transportées sur un plan axial par rapport au rotor par un courant dair contrôlé de sorte quils atteignent un site dévacuation où un ventilateur dévacuation est monté. Langle de lévacuation autour de laxe de rotor peut être modifié afin de diriger les graines vers le côté de la moissonneuse-batteuse éloigné dun broyeur de paille, vers les palettes de guidage du plan incliné de la hacheuse-ensileuse ou dans le boîtier du broyeur de paille.
Patent CA-3104099-A1 (CA)
Inventor: HUNTLEY C FREDERICK M
IPC: A61K31/485
Filed: 2016-03-09
Abstract: ABSTRACT OF THE DISCLOSURE The present disclosure provides acetate salts of buprenorphine, and its anhydrates, solvates, hydrates, and crystalline forms thereof, where the acetate salts of buprenorphine are essentially free of impurities. The disclosure further provides method of preparing the acetate salts, buprenorphine free base prepared from the acetate salts, other salts prepared from the free base, and pharmaceutical compositions thereof essentially free of impurities.   Date Recue/Date Received 2020-12-23
Patent CA-3106821-A1 (CA)
Inventor: CORNES STEPHEN
IPC: C07F9/24
Filed: 2019-07-19
Abstract: A process for the manufacture of intermediates of the insecticide acephate (i.e., N-(methoxy-methylsulfanylphosphoryl) acetamide) is described. The conversion of O-methyl phosphorodichloridothioate ("mono-ester") to O,O-dimethylphosphorochloridothioate ("DMPCT"), and the conversion of DMPCT to O,O-dimethylphosphoroamidothioate ("DMP AT") are performed in a continuous process without isolating either DMPCT or DMPA T, thus resulting in enhanced safety over previously utilized methods.
Patent CA-3108913-A1 (CA)
Inventor: CONKLIN BRIAN S
IPC: A61B17/04
Filed: 2019-08-27
Abstract: Systems, apparatuses, and methods disclosed herein are provided for medical treatment, including transcatheter medical treatments and/or for treatment of dilated hearts (e.g., dilated left ventricle) or functional mitral valve regurgitation within a human heart. The systems, apparatuses, and methods disclosed herein may include applying one or more heart splints to the patient's heart to apply pressure to the heart to reshape the heart. Anchors disclosed herein may be utilized in plugs for treating openings in a septum between two chambers of a heart, e.g., ventricular septal defects (VSD), atrial septal defects (ASD), and patent foramen ovale (PFO). In addition, the anchors disclosed herein may be utilized to reshape an annulus of a patient's heart valve, including a tricuspid valve of a patient's heart. The anchors disclosed herein may also be utilized to reposition a heart valve leaflet to reduce heart valve leaflet prolapse.
Patent CA-3112235-A1 (CA)
Title: Embout buccal pour fumer et appareil pour fumer comprenant un tel embout buccal pour fumer
Inventor: SARAC GEORG
IPC: A24F1/30
Filed: 2019-07-28
Abstract: La présente invention concerne un embout buccal pour fumer (1) comprenant une première partie tubulaire (3a), de préférence rigide en flexion, présentant une première extrémité libre (2a) et une deuxième partie tubulaire (3b), de préférence rigide en flexion, présentant une seconde extrémité libre (2b), la première partie tubulaire (3a) pouvant être raccordée à l'appareil pour fumer (4) et la deuxième partie tubulaire (3b) étant prévue pour être introduite dans la bouche d'un fumeur, et les première et deuxième parties tubulaires (3a, 3b) étant conçues pour être sensiblement droites, une troisième partie tubulaire (3c) flexible étant prévue entre les parties tubulaires (3a, 3b). L'invention concerne également un appareil pour fumer (4) comprenant un tel embout buccal pour fumer (1).
Patent CA-3112243-A1 (CA)
Title: Magnetic cleaning apparatus and method of use thereof
Inventor: PATON Mark
IPC: E21B31/06
Filed: 2019-09-16
Abstract: The present invention relates to a magnetic cleaning tool (100) for removing ferrous debris from within a BOP, riser or wellbore, the tool comprising: a tool body having a longitudinal axis, and one or more magnets (104) configured to rotate around an axis substantially parallel to the longitudinal axis from a first position to a second position. In the first position the one or more magnets attract ferrous debris to a debris gathering surface, and in the second position the one or more magnets do not attract ferrous debris to the debris gathering surface.
Patent CA-3112911-A1 (CA)
Title: Dispositif d'eclairage de casque de securite
Inventor: KIM SUNG GYU
IPC: H02J7/00
Filed: 2018-09-20
Abstract: La présente invention concerne un dispositif d'éclairage de casque de sécurité et, plus particulièrement, un dispositif d'éclairage de casque de sécurité qui, en plus de pouvoir fournir un éclairage pour permettre à un utilisateur de continuer à regarder vers l'avant, peut indiquer l'emplacement d'un utilisateur en émettant de la lumière à partir de toute la surface d'un cadre annulaire, et indiquer un objet distant à l'aide d'un pointeur laser. Le dispositif d'éclairage de casque de sécurité selon la présente invention comprend : un cadre annulaire destiné à être monté sur la surface circonférentielle extérieure d'un casque de sécurité ; plusieurs parties électroluminescentes disposées sur le côté extérieur du cadre ; une batterie pour fournir de l'énergie ; un dispositif de commande pour commander la luminosité et la couleur des parties électroluminescentes ; et un moyen de contact étroit pour empêcher la séparation du cadre et du casque de sécurité.
Patent CA-3114931-A1 (CA)
Title: Conjugues anticorps-medicament modulateur d'epissage d'herboxidiene et procedes de utilisation
Inventor: FISHKIN NATHAN
IPC: A61P37/04
Filed: 2019-12-12
Abstract: L'invention concerne des composés lieur-médicament et des conjugués anticorps-médicament qui se lient à des cibles oncologiques humaines. Les composés lieur-médicament et les conjugués anticorps-médicament comprennent un fragment de médicament modulateur d'épissage d'herboxidiène. L'invention concerne en outre des procédés et des compositions destinés à être utilisés dans le traitement de troubles néoplasiques par administration des conjugués anticorps-médicament décrits dans l'invention.
Patent CA-3115577-A1 (CA)
Inventor: SCHULTZE TORSTEN
IPC: H04L27/26
Filed: 2018-10-29
Abstract: A method of recovering information encoded by a modulated sinusoidal waveform having first, second, third and fourth data notches at respective phase angles, where a power of the modulated sinusoidal waveform is reduced relative to a power of an unmodulated sinusoidal waveform within selected ones of the first, second, third and fourth data notches so as to encode input digital data. The method includes receiving the modulated sinusoidal waveform and generating digital values representing the modulated sinusoidal waveform. A digital representation of the unmodulated sinusoidal waveform is subtracted from the digital values in order to generate a received digital data sequence, which includes digital data notch values representative of the amplitude of the modulated sinusoidal waveform within the first, second, third and fourth data notches. The input digital data is then estimated based upon the digital data notch values.
Patent CA-3116024-A1 (CA)
Title: System and method for cutting sheets for use in the production of boxes
Inventor: BARNETT MICHAEL
IPC: B26D1/62
Filed: 2021-04-22
Abstract: In one aspect, there is provided a combination for use in readying a cutting cylinder is rotatably mounted to a frame in a box-forming production line. The cutting cylinder has a cylinder reference indicium. The combination includes a transfer member with a transfer member reference indicium thereon, a cutting member that includes a base and a cutting blade, and a connector structure that is configured to releasably mount the cutting member to the transfer member. The cutting member is movable to a selected distance along the first axis from the transfer member reference indicium. The connector structure includes a locking structure positionable in an unlocking position for separating the cutting member and the transfer member, and a locking position to lock the connector structure to the transfer member, so as to hold the cutting member at the selected distance from the transfer member reference indicium.
Patent CA-3116604-A1 (CA)
Inventor: HERTEL PATRIK
IPC: B65G39/16
Filed: 2019-10-24
Abstract: Method of adjusting and tracking an conveyor belt arranged around at least two rotatable drums, the belt having a direction of travel along its length and orthogonally an axis of the at least two drums, whereby the adjustment of the belt is made by displacing at least one of the drums sideways seen in the direction of travel of the belt and thus the belt so that the belt directly gets into a desired position. A conveyor belt tracking arrangement, the drums are arranged with their axles in a frame and at least one drum is arranged with its axle in a pivot frame and the pivot frame is in turn adjustably arranged in the frame, and movable by means of a drum moving force, which in turn makes the whole drum, with the belt, to move with the pivot frame around a pivot point provided in an orthogonal plane along the centre of the belt seen in the direction of the belt at a distance from the drum, so that the belt is directly moved to a desired position.
Patent CA-3119394-A1 (CA)
Title: Monobactam compounds and use therefor
Inventor: WANG YONG
IPC: A61K31/437
Filed: 2019-11-12
Abstract: Monobactam compounds and a use therefor. Specifically provided are chemical compounds represented by formula (I) or isomers, pharmaceutically acceptable salts, solvates, crystals, or prodrugs thereof, preparation methods therefor, pharmaceutical compositions containing said compounds, and a use of said compounds or compositions in treating bacterial infection. The present compounds feature excellent antibacterial activity, and have great hopes of becoming a therapeutic agent for bacterial infection.
Patent CA-3122719-A1 (CA)
Inventor: MISTRY MAYUR
IPC: H01M8/1018
Filed: 2020-01-17
Abstract: The present invention provides a proton exchange membrane comprising an ion-conducting layer which comprises an ion-conducting polymer and a supported recombination catalyst, wherein the recombination catalyst is supported on graphene.
Patent CA-3122756-A1 (CA)
Title: Methods and compositions for treating hyperoxaluria
Inventor: RUSS ZACHARY NICHOLAS
IPC: C12N15/74
Filed: 2019-12-10
Abstract: The disclosure relates generally to bacteria that have been modified to have increased oxalate degrading activity, pharmaceutical compositions including the bacteria, and methods of treating disorders associated with an elevated amount of oxalate, e.g., hyperoxaluria.
Patent CA-3123325-A1 (CA)
Inventor: CHEN CHAO
IPC: C12N15/62
Filed: 2020-03-04
Abstract: La présente invention concerne un polypeptide FGF21, qui a une ou plusieurs des propriétés suivantes : une structure stable, une longue demi-vie, une faible immunogénicité, une activité biologique élevée, et des activités améliorées d'abaissement du glucose et d'abaissement des lipides. La présente invention concerne également une protéine de fusion ou un immunoconjugué comprenant le polypeptide FGF21 décrit ici.
Patent CA-3125434-A1 (CA)
Title: Go-bag for emergency situations
Inventor: LECOCKE MEREDITH BEVERIDGE
IPC: A45F3/00
Filed: 2019-12-17
Abstract: A go-bag is disclosed. The bag is designed to contain valuables and important documents, and protect these contents during an emergency evacuation situation. The bag can waterproof and float in water. The bag can also be made of a flame resistant material. The bag can include a self-orienting feature where the bag can float in water and automatically rotate to achieve the proper orientation so that the integrated solar panel is facing upwards towards the sun.
Patent CA-3126036-A1 (CA)
Title: Patency checking system
Inventor: MA YIPING
IPC: A61M5/145
Filed: 2020-01-16
Abstract: A patency checking system, may include a fluid path to be coupled to an intravenous (IV) device at a distal end of the fluid path; a patency port formed along a length of the fluid path; and a plunger fluidically coupled to the fluid path at the patency port to selectively draw blood into the fluid path to confirm patency of the fluid path.
Patent CA-3127712-A1 (CA)
Inventor: VAN DER KAAP JORDY
IPC: B65H54/58
Filed: 2020-01-16
Abstract: A coiler for producing tighter or smaller coils of dunnage uses a cam to move fork pins from a dunnage-receiving position inwardly to a more closely-spaced coiling position. The fork pins are coupled to pin mounts that cooperate with the cam and slots in a guide plate to move the parallel fork pins between the dunnage-receiving and coiling positions. The fork pins are mounted to extend perpendicular to and through the guide plate on opposing sides of a path of the dunnage to capture and wind a dunnage strip into a coil.
Patent CA-3128976-A1 (CA)
Title: Fire resistant polyurethane coating composition and a fire-resistant product comprising the same
Inventor: TAI XIANGYANG
IPC: C08L75/08
Filed: 2019-02-11
Abstract: A fire-resistant polyurethane composition and a fire-resistant product comprising the fire-resistant polyurethane composition. The fire-resistant polyurethane coating composition comprises: an aromatic isocyanate component, a polyol component, and an intumescent component; wherein the aromatic structure in the polyurethane backbone is =24wt%. The fire-resistant polyurethane composition could provide surprisingly good intumescent layer toughness as well as good insulation performance.
Patent CA-3131760-A1 (CA)
Inventor: ZHOU LICHANG
IPC: C08F2/22
Filed: 2020-04-14
Abstract: Processes to prepare aqueous polymer dispersions are provided, as well as compositions thereof, which have high solids content (<i>e.g</i>., 50%) with low viscosity. The process uses a selective hydrophilic macro-RAFT agent of formula (I), and is substantially free of surfactants. This process can be used to make latex polymers with good stability, which can be used widely in coatings (<i>e.g</i>., architectural paints, stone paints, industrial coatings, wood coatings, <i>etc</i>.), adhesives, sealants and mastic compositions.
Patent CA-3131964-A1 (CA)
Title: A liquid air rotary engine
Inventor: ANTROBUS CRAIG
IPC: F01C21/06
Filed: 2021-09-26
Abstract: A Rotary engine power system that is powered by the transformation of Liquid Air from its liquid state into a Gas state. A Rotary Engine that is mechanically similar to existing conventional rotary engines but highly modified to increase air temperatures and pressures to compensate for the cold temperatures of the liquid air expansion.  A Rotary engine that should comprise of four rotors so that there is an expansion reaction every 30 degrees of rotor movement.
Patent CA-3132373-A1 (CA)
Inventor: STEVENS BRANDON M
IPC: H01R24/40
Filed: 2020-03-05
Abstract: La présente invention concerne un connecteur radiofréquence (RF) ayant un système de protection contre les intempéries intégré pour protéger le connecteur contre l'eau, la glace, le sel, les débris et d'autres dommages étrangers. Le connecteur comprend un ensemble de protection contre les intempéries (WP) entourant un corps de connecteur, qui, à son tour, est monté de manière étanche sur un câble coaxial. L'ensemble WP comprend un boîtier, une bague d'étanchéité souple et un élément de sollicitation. Le boîtier WP est monté de manière étanche sur une extrémité du corps de connecteur et définit une ouverture à une extrémité opposée de celui-ci pour recevoir le câble coaxial et faciliter la translation axiale du boîtier par rapport au corps de connecteur. La bague d'étanchéité souple a une surface d'étanchéité tournée vers l'intérieur qui définit une dimension de diamètre. Et, l'élément de sollicitation peut être reconfiguré d'un état étendu à un état plié en réponse à un déplacement axial du boîtier par rapport au corps de connecteur. De manière opérationnelle, l'élément de sollicitation vient en prise avec la bague élastique pour étendre la dimension de diamètre de l'élément de sollicitation autour d'une partie d'un orifice d'interface, et se ferme sur une surface d'étanchéité de l'orifice d'interface pour sceller l'anneau souple contre la surface d'étanchéité.
Patent CA-3133966-A1 (CA)
Inventor: BRYANT AIDAN
IPC: F16K17/16
Filed: 2020-03-17
Abstract: A valve assembly for use with a container such as a fuel tank. Embodiments of the assembly include an inlet and outlet provided on separate sides of the central axis of a housing, the housing being connected to a central conduit located in a container. The valve assembly includes inlet and outlet valves which allow the venting of air during filling and the intake of air as fuel is consumed. The valve assembly is arranged so that air flows through a less torturous path compared to known prior art, enabling a high rate of filling to be achieved.
Patent CA-3137443-A1 (CA)
Title: Rechargeable battery comprising a sulfur dioxide-based electrolyte
Inventor: ZINCK LAURENT
IPC: H01M10/0568
Filed: 2020-04-07
Abstract: The invention relates to a rechargeable battery cell comprising a housing (1), at least one positive electrode (4), at least one negative electrode (5) and an electrolyte, which contains at least one conductive salt, which electrolyte is based on SO2 and which positive electrode contains an active material of the composition AxM'yM"z(XO4-mSn), where A is an alkali metal, an alkaline earth metal, a metal of group 12 of the periodic table or aluminum, preferably sodium, calcium, zinc, particularly preferably lithium, M' is at least one metal selected from a group consisting of the elements titanium, vanadium, chromium, manganese, iron, cobalt, nickel, copper and zinc, M" is at least one metal selected from the group consisting of the metals of groups 2, 3, 4, 5, 6, 10, 11, 12, 13, 14, 15 and 16 of the periodic table, X is selected from a group consisting of the elements phosphorus and silicon, x is greater than 0, y is greater than 0, z is greater than or equal to 0, n is greater than 0 and m is less than or equal to n.
Patent CA-3138106-A1 (CA)
Title: Pneumatic tool with gear train
Inventor: PATTERSON MATTHEW D
IPC: F16H1/28
Filed: 2021-11-08
Abstract: The present invention relates broadly to pneumatic tools, such as a sander, that provide an optimum output speed and has significant stall torque to reduce the risk of the tool from stalling during use. The tool includes a coupled gear set that drives an output accessory, such as an abrasive pad, at an optimum speed without loss of power or power reduction, and with an amplified stall torque. The coupled gear set may include a first gear set that functions as a speed reducer, and a second gear set that functions as a speed increaser.
Patent CA-3142011-A1 (CA)
Title: Use of an anti-p-selectin antibody
Inventor: LAINE DRAM
IPC: A61K39/395
Filed: 2020-06-05
Abstract: The invention relates to a method of treating priapism in a patient in need of such treatment, comprising administering a pharmaceutically effective amount of an anti-P-selectin antibody or a binding fragment thereof to said patient, especially wherein the patient is suffering from Sickle Cell Disease (SCD), and related invention embodiments (uses, methods, pharmaceutical preparations and use in the preparation of pharmaceutical preparations).
Patent CA-3142613-A1 (CA)
Title: System for wall construction
Inventor: CICCARELLO CHARLES
IPC: E04B2/02
Filed: 2020-06-05
Abstract: A kit and system for constructing structures including at least one core block, at least one fascia block that connects to the core block by mounting a shelf that extends from a face of the core block with a cut-out section of a face of the fascia block, such that the face of the core block and the face of the fascia block form a gap therein between.
Patent CA-3143450-A1 (CA)
Title: Compositions and methods to potentiate musculoskeletal effect of one or more anabolic amino acids
Inventor: FEIGE JEROME
IPC: A61K45/06
Filed: 2020-06-19
Abstract: A method of potentiating musculoskeletal effect of one or more anabolic amino acids in an individual in need thereof can include administering to the individual in need thereof a composition containing the one or more anabolic amino acids, the composition also containing one or more autophagy-inducing compounds in a total amount effective for the composition to be at least neutral regarding autophagy. In another aspect, a method of overcoming one or more negative effects of one or more anabolic amino acids by preventing degenerative processes related to loss of autophagy can include administering to an individual in need thereof a composition containing the one or more anabolic amino acids, the composition further containing the one or more autophagy-inducing compounds in a total amount effective for the composition to be at least neutral regarding autophagy.
Patent CA-3145268-A1 (CA)
Inventor: CEYLAN ISMAIL
IPC: C07D213/34
Filed: 2020-07-31
Abstract: La présente invention concerne de nouveaux composés aminoesters ou leurs sels pharmaceutiquement acceptables ou isomères optiques, racémates, diastéréoisomères, énantiomères ou tautomères. La présente invention concerne également leur procédé de préparation et ces composés destinés à être utilisés en tant que médicament, en particulier pour le traitement ou la prévention du cancer. La présente invention concerne en outre un conjugué anticorps-médicament comprenant de tels composés.