baber/WOPTO huggingface dataset:
Patent SG-11201909856X-A (SG)
Title: Mesenchymal lineage precursor or stem cells with enhanced immunosuppression
Inventor: ITESCU SILVIU
IPC: C12N5/0775
Filed: 2018-05-04
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 08 November 2018 (08.11.2018) WIPO I PCT omit VIII °nolo Hololloiolimiolionom oimIE (10) International Publication Number WO 2018/202853 Al (51) International Patent Classification: C12N 5/0775 (2010.01) (21) International Application Number: (22) International Filing Date: PCT/EP2018/061503 Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) 04 May 2018 (04.05.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 2017901633 04 May 2017 (04.05.2017) AU 2017901636 04 May 2017 (04.05.2017) AU 2018900551 21 February 2018 (21.02.2018) AU (71) Applicant: MESOBLAST INTERNATIONAL SARL [CH/CH]; c/o Accounting and Management Services SA, Route de Pre-Bois 20, 1217 Meyrin (CH). (72) Inventors: ITESCU, Silviu; c/o Level 38, 55 Collins Street, Melbourne, Victoria 3000 (AU). SIMMONS, Paul; c/o Level 38, 55 Collins Street, Melbourne, Victoria 3000 (AU). (74) Agent: MULLER, Christian; ZSP Patentanwalte PartG mbB, Hansastr. 32, 80686 Miinchen (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). 00 O (54) Title: MESENCHYMAL LINEAGE PRECURSOR OR STEM CELLS WITH ENHANCED IMMUNOSUPPRESSION 00 (57) : The present disclosure relates to cellular therapy products comprising mesenchymal lineage precursor or stem cells and O potency assay for these products. The present disclosure also relates to methods for treatment of immune or inflammatory disorders, and treatment or prevention of graft versus host disease (GVHD), or one or more symptoms associated with GVHD, by administration C of mesenchymal lineage precursor or stem cells.
Patent HU-182272-B (HU)
Title: Process for preparing rhanitidine
Inventor: BRADSHAW JOHN
IPC: C07D203/12
Filed: 1981-01-08
Abstract: The invention relates to a process for the preparation of ranitidine of the formula: <IMAGE>  which is characterised in that a thiol of the formula: <IMAGE>  is reacted with an alkylating agent of the formula: <IMAGE> in which R1 denotes the group -CH2CH2L, where L represents a leaving group, and R2 represents a hydrogen atom or R1 and R2, together with the nitrogen atom to which they are attached, form an ethyleneimino group.
Patent YU-46685-B (YU)
Inventor: DORE F
IPC: C01F7/786
Filed: 1990-01-11
Abstract: PCT No. PCT/EP90/00050 Sec. 371 Date Sep. 18, 1990 Sec. 102(e) Date Sep. 18, 1990 PCT Filed Jan. 10, 1990 PCT Pub. No. WO90/08738 PCT Pub. Date Aug. 9, 1990.The present invention relates to a process for preparing basic aluminum compounds having the general formula (1) [Al2 (OH)x Cly (SO4)z]n (1) where: n is at least equal to 1 x=2-4.0 y=2.0-3.40 z=0-0.30 and x+y+z=6 by means of a reaction of alumina with hydrochloric acid, possibly mixed with sulfuric acid. The alumina is caused to react in alumina/acid(s) stoichiometric conditions to obtain the compounds of formula (1). The reaction is carried out by milling alumina in liquid phase under heavy stirring.
Patent AT-397826-B (AT)
Title: Add-on device (attachment) for a snow-clearing apparatus which can be coupled to a commercially available motor vehicle having a driver's cab provided at one end
IPC: E01H5/09
Filed: 1989-04-10
Granted: 1994-07-25
Abstract: The add-on device (attachment) is provided for a snow- clearing apparatus 2 which can be coupled at the front to a commercially available motor vehicle 3 having a driver's cab 8 provided at one end. It has an add-on frame 7 which can be fastened to the motor vehicle 3, and to which the snow-clearing apparatus 2 is articulated such that it can be raised and lowered via at least one pair of levers 4, 5. The add-on frame 7, formed from two lateral load bearing rails and two transverse struts, is arranged underneath the driver's cab 8, where the drive motor of the motor vehicle 3 is normally provided. The plane of the frame is essentially vertical. The drive shaft 68, which connects the snow-clearing apparatus 2 to a drive unit 39 arranged in the region of the rear axle of the motor vehicle 3 is led through the add-on frame 7. <IMAGE>
Patent AT-385149-B (AT)
Title: Multipart electrical fused plug
IPC: H01R13/68
Filed: 1985-03-26
Granted: 1988-02-25
Abstract: In a multipart electrical fused plug having a fuse element which is arranged under a screw cap, a fixed installed fused element is arranged in the plug upper part opposite the plug pins which are located in the plug lower part. The plug upper part and plug lower part are connected to one another by means of screws, with the electrically conductive connection being produced at the same time from the plug pins via the socket, the pressure pin, the miniature fuse (fine fuse, picofuse) and via the plug contact to the terminals for a connecting cable, and access to the terminals for the connecting cable being made possible by lifting off the upper part. <IMAGE>
Patent CH-626500-B (CH)
Inventor: ZUMSTEG ALPHONSE
IPC: G04G3/02
Filed: 1980-01-10
Abstract: The oscillator circuit comprises a digital temperature compensation circuit connected to a low and a high frequency quartz oscillator. The two quartz oscillators have the same inversion temperature points and a different temperature behaviour. In the temperature compensation circuit a beat frequency is produced between the divided signal of the high frequency oscillator and the frequency of the low frequency oscillator and then fed to a correction circuit and multiplied therein with a correction factor which has been stored in a PROM. The obtained correction signal is fed into the frequency divider chain for obtaining a temperature compensated outgoing signal for use in a timer circuit. The temperature compensation circuit is simply designed and allows high accuracy, which is particularly well suited for a wristwatch or a photo camera.
Patent HU-183822-B (HU)
Title: Method for making the coil of dual-motor electric drives, preferably for automatic washing machines
Inventor: BRADLER PETER
IPC: H02K17/16
Filed: 1982-02-12
Abstract: 1. Winding for an electric motor, especially for an automatic washing machine, with a stator winding in a common laminated stator core and arranged in slots, on the one hand of a universal motor with pole pair number Pu = 1, and on the other hand of an induction motor with pole pair number PI >= 2 and with a common rotor, of which the winding, arranged in slots, is designed as follows : It consists : a) of electric circuits with a pole number which corresponds to that of the energising induction motor stator field, these electric circuits having at least two coil groups with coils of the same coil turn number, connected in each case in series to a shorted circuit, and b) of electric circuits connected to the segments of a commutator and with a pole number which corresponds to that of the energising universal motor stator field and in which the total slot number of the rotor is different from the slot number determined on the basis of pole number, phase number and number of slots per pole and phase for one integral slot-winding according to the formula : N2 = 2p . m2 . q2 , characterised by the features : c) the coil width wI of one coil of every coil group corresponds, as precisely as made possible by the slot distribution, to the simple pole distribution of the induction motor winding, d) the number n2 of the coils per coil group totals : n2 = PI/k with k = 1, 2, 3..., e) the spatial angular distance between two consecutive coils of a coil group amounts to : alpha = 360 degrees/n2 , f) universal motor winding and induction motor winding are completely electrically isolated from each other, g) winding coil groups to be wound successively by a winding mechanism are wound continuously with a continuous wire, which, at the transition from the winding end of one coil group to the winding beginning of the other, contacts a short-circuiter which connects all the winding ends/winding beginnings.
Patent HU-213403-B (HU)
Title: Process for producing penem esters derivatives and pharmaceutical compositions having antibacterial activities containing the same
Inventor: ISHIGURO MASAJI
IPC: C07D499/887
Filed: 1991-08-16
Abstract: Novel antibacterial penem esters are methyl (5R,6S)-6-Ä(R)-1-hydroxyethylÜ-2-Ä(R)-2-tetrahydrofurylÜ-penem-3-carbo xylates having at the 3-position an ester group of the formula -COOR in which R represents -CH2OCO-Y or -CH2-Z in which Y is a tetrahydrofuryl group; a tetrahydropyranyl group; a 1,3-dioxolanyl group; a 2-oxo-1,3-dioxolanyl group; or a 1,4-dioxanyl group and Z is a 5-(C6-C10 aryl or C7-C11 aralkyl)-2-oxo-1,3-dioxolen-4-yl group. Other substituted-methyl (5R,6S)-6- Ä(R)-1-hydroxyethylÜ-2-Ä(R)-2-tetrahydrofurylÜ-penem-3-carboxylates are disclosed.
Patent LT-4782-B (LT)
Title: Heat and moisture recovery device
Inventor: MIGAUSKAS JUOZAPAS
IPC: F04D25/00
Filed: 1999-07-23
Abstract: Invention belongs to the area of heat recuperators and may be used in the systems of ventilation and recuperation. Heat and humidity recuperation device consists of two or more heat-transmitters each of which has the incoming airflow (A) intake (a) and the outgoing airflow (B) outtake (b). Heat transmission walls separate both air flows, where the intake (a) of the heat-transmitter (1) is connected to the intake (A) of the recuperating device. The outflow (b) is connected by the heat-transmitter (1) to the intake (a) of the heat transmitter (2), the intake (b) of the heat heat-transmitter (1) is connected to the outflow b of the heat transmitter (2).
Patent AT-398904-B (AT)
Title: Implantable catheter
Inventor: GEORGI AXEL DR ING
IPC: A61M25/00
Filed: 1990-06-13
Granted: 1995-02-27
Abstract: The invention relates to an implantable catheter for administering liquid drugs. At the distal end 3 of the catheter is arranged a tuft 4 which consists of carbon fibre and which runs essentially in the direction of the longitudinal axis of the catheter. It is expedient if the weight-related fibre surface is greater than 35 m2/g. This design of the distal end 3 rules out accretions at the outlet orifice and therefore interruptions in the administration of the drugs. <IMAGE>
Patent AT-399729-B (AT)
IPC: D01D5/088
Filed: 1993-07-01
Granted: 1995-07-25
Abstract: To prepare cellulose fibres, a solution of cellulose in a tertiary amine-oxide is shaped in hot condition to give filaments, the filaments are cooled and then introduced into a precipitation bath in order to precipitate the dissolved cellulose, whereby the shaped solution is exposed to an essentially laminar gas stream (FIG. 2a) for cooling before introduction into the precipitation bath.
Patent AT-407706-B (AT)
Inventor: EIBL JOHANN DR
IPC: A61K38/48
Filed: 1994-07-01
Granted: 2001-05-25
Abstract: A treatment of ischemia and the attendant reperfusion injury entails the administration plasmin and plasmin-forming proteins, including lys-plasminogen and similar substances. Lys-plasminogen, which can be obtained from the proteolytic cleavage of glu-plasminogen, has been found to have a protective effect on tissue that has been injured by ischemic conditions. The administration of lys-plasminogen can used to treat subjects during the time of reperfusion and after reperfusion has already occurred. Lys-plasminogen also can be administered in conjunction with clot lysis therapies, such as those that employ tissue plasminogen activator and the like. <IMAGE>
Patent AT-408754-B (AT)
Title: Method for composting organic materials
Inventor: KITA FIROOZ
IPC: C05F17/00
Filed: 1996-11-06
Granted: 2002-03-25
Abstract: The invention relates to a method for composting organic materials with the following steps: - precomminuting the material, - first conversion of the material during mechanical treatment, - second conversion and decomposition into compost. The method is characterized in that, after the material has been precomminuted, a first screening step is carried out for eliminating raw materials, and in that, after the first conversion, a second screening step is carried out. <IMAGE>
Patent AT-396290-B (AT)
Title: Heated hot-water store
IPC: F24H9/12
Filed: 1988-09-09
Granted: 1993-07-26
Abstract: Heated hot-water store with a device for discharging the excess water resulting from thermal expansion of the stored water into the water outflow, and a tapping point which is arranged on the water outflow and which is connected to the hot-water store 1 via a line 7 provided with a tapping valve 8. Between the line string 2 leading from the hot-water store 1 to the tapping point and the outflow line 6 serving for the outflow of water from the collecting basin 4 of the tapping point there is provided a line connection 9, in which is located a valve 10 which is capable of being closed by the water tapping pressure, but otherwise remains open. <IMAGE>
Patent DK-164498-B (DK)
Inventor: LEE LEN FANG
IPC: C07D211/60
Filed: 1991-10-04
Abstract: An improved process for the preparation of a compound of the formula   <CHEM> wherein X is NH; R1 is selected from lower alkyl, phenyl, heterocyclic radicals having 3-6 atoms in the ring with 1-3 atoms selected from O, S, and N; R2 is a C1-4 alkyl radical and R3 represents a C1-4 fluoroalkyl radical, comprises reacting a 3-ketoester with an aldehyde in the presence of piperidine as a catalyst to form a corresponding pyran, i.e. a compound of the above formula in which X is oxygen, and then passing gaseous ammonia through the reaction mixture to react therewith to produce the desired compound.
Patent DK-150584-B (DK)
Inventor: NIELSEN JENS PETER
IPC: E04D/
Filed: 1985-05-08
Abstract: A sloping roof structure comprises a supporting structure (72) and a plurality of elastically flexible, outwardly convexly curved roofing plates (74) mounted thereon. The roofing plates are mounted in a partly overlapping relationship so that the lower rim portion of each plate overlaps the upper rim portion of an adjacent lower plate. Each roofing plate is fastened to the supporting structure by means of nails (75), screws or other fastening means at a portion intermediate of the upper and lower rim portions of the plate. The initially curved plate is fixed in an at least partly flattened condition, whereby the upper and lower rim portions are resiliently pressed against the supporting structure (72) and the outer surface of the adjacent lower plate, respectively. The curved roofing plates (74) for such a roof structure may be made from a layer (37) of a plastic, deformable material, such as a cement mixture which may be reinforced by fibers. This layer of material may be placed on a curved supporting surface (70) so that the layer of material attains a shape similar to that of the supporting surface. The layer of material may then be hardened or set while supported by the curved supporting surface.
Patent DK-165247-B (DK)
Inventor: SATZINGER GERHARD
IPC: C07D213/80
Filed: 1985-08-23
Abstract: The present invention describes 1,6-naphthyridine derivatives of the general formula:   <IMAGE>   wherein R1 is an unsubstituted or substituted aromtic or heteroaromatic ring, R2 is a straight-chained or branched alkyl radical containing up to four carbon atoms or a benzyl radical, R3 is a hydrogen atom, a straight-chained or branched alkyl radical or an alkoxycarbonyl radical containing up to four carbon atoms, R4 is a straight-chained or branched alkyl radical containing up to four carbons and R5 is a carbonyl group or a straight-chained, branched or cyclic alkoxycarbonyl radical which contains up to 17 carbon atoms and optionally also contains an oxygen, sulphur or nitrogen atom; as well as the pharamacologically acceptable salts thereof, which are useful for treating diseases of the blood vessels.
Patent DK-151095-B (DK)
Title: Packaging for coiled products and method for the manufacture thereof
Inventor: CEDENBLAD BJOERN
IPC: B65D85/04
Filed: 1984-09-25
Abstract: PCT No. PCT/SE84/00024 Sec. 371 Date Sep. 21, 1984 Sec. 102(e) Date Sep. 21, 1984 PCT Filed Jan. 26, 1984 PCT Pub. No. WO84/02893 PCT Pub. Date Aug. 2, 1984.A package for products to be coiled such as ropes, hoses, cables, flexible tubing and similar kinds of products which are available by the yard coiled into a ring-shaped bundle (1). The package according to the invention comprises a supporting carrying construction (2) mounted on one side of the ring-shaped bundle (1). The supporting construction (2) can comprise an inner annular flat slab (3) the inside diameter of which essentially corresponds to the inside diameter of the ring-shaped bundle (1), and an outer (4) flat slab engaging the inner slab (3). The outer slab has a circular opening, the diameter of which is somewhat smaller than the outside diameter of the inner slab (3). The inner slab (3) is disposed concentrically with the circular opening of the outer slab (4) which it overlaps. To the outer slab (45) and the inner slab (3) a number of flexible bands (5) are fixed which extend outwards from the outer slab and inwards from the inner slab and which are of such length, that the bands (5A, 5B) after having been bent over the ring-shaped bundle (1) and fixed to one another, surround and retain the ring-shaped bundle (1) in cooperation with the supporting construction (2). The invention also relates to a method for manufacturing said package. According to the method the supporting construction (2) is disposed at one end of a rotatable coiling matrix perpendicularly to the rotation axis thereof. The product to be coiled is coiled on the matrix in close proximity to the supporting construction, and when a sufficient length has been coiled, the free ends (5A, 5B) of the band (5) are bent around the ring-shaped bundle thus formed and are clamped at one another on the opposite side of the bundle. The ring-shaped bundle can then be removed from the matrix as a package ready for delivery.
Patent DK-165859-B (DK)
Title: Apparatus for determining an analyte in a biological fluid
Inventor: GRENNER GERD
IPC: G01N33/52
Filed: 1987-11-24
Abstract: A biological diagnostic device and process for efficiently and accurately analyzing for an analyte of interest in a sample of a biological fluid. The device, which in a preferred embodiment is utilized for the analysis of whole blood samples, comprises a diagnostic test element and a sample application unit comprising a filter element and a fluid delivery element which is in fluid contact with the test element. The delivery element comprises a layer having a plurality of grooves, or channels, in the surface thereof which is adjacent the filter element. The fluid which passes through the filter is collected in the grooves of the delivery element and subsequently delivered to the test element.
Patent FI-76364-B (FI)
Inventor: ZDANOWSKI RICHARD EDWARD
IPC: C09G1/16
Filed: 1984-03-29
Granted: 1988-06-30
Abstract: Polymer compositions which are useful as polishes or polish polymer vehicles, especially floor polishes or vehicles therefor, contain emulsion copolymer containing from 3% to 50% by weight of units of acidic monomer, transition metal ionic crosslinking agent in an amount of at least 15% of the equivalent of the copolymer acid residues, and at least one basic salt or hydroxide or alkali metal in such an amount that the molar ratio of transition metal to alkali metal is from 10:0.1 to 1.0:3.0. 
<??>The presence of the alkali metal compound increases the wear resistance properties of films of the polish.
Patent FI-79022-B (FI)
Inventor: KLUEPPEL HANS-JUERGEN
IPC: A61K31/14
Filed: 1984-12-14
Granted: 1989-07-31
Abstract: Oral and dental hygiene preparations containing quaternary ammonium compounds of the formula    <IMAGE>  (I)  wherein R1 is an n-alkyl group, preferably containing from 8 to 12 carbon atoms, R2 is hydrogen, a CH3-group or a CH2OH-group and R3 is a CH3-group or a group of the formula -CH2-CH(OH)-R2, A is an inorganic or organic acid anion and n is the basicity of the anion. The quaternary ammonium compounds of formula I can have a plaque inhibiting effect and show only slight antimicrobial activity. R1 is preferably an n-decyl group, R2 is hydrogen and R3 is a CH3-group or a 2-hydroxyethyl group. The oral and dent al hygiene preparations also preferably contain fluorides and/or organophosphonates as the anion A.
Patent FI-73091-B (FI)
Inventor: VIRTA ARTO
IPC: A61B6/14
Filed: 1985-05-31
Granted: 1987-04-30
Abstract: @ A panoramic tomography X-ray apparatus, which comprises a fixed frame (30), to which another frame (rotary frame) (11), having an X-ray tube (10) at one end and a film cartridge device (20) for X-ray film (RF) at the other end, is suspended. The apparatus has a drive mechanism forturning the rotary frame (11) in the horizontal plane for taking a panoramic X-ray photograph. In the drive mechanism there is a drive and guide groove (31), which has straight side sections (31S) and a curved section (31 R) connecting the side sections together. The drive unit (33) of the apparatus comprises a drive wheel (40) which, when rotated by the drive unit (33), turns said rotary frame (11). The rotary frame (11) is suspended to the fixed frame (30) by means of a crank mechanism (13,50,51) which is jointed to the rotary frame (11) and to the fixed frame (30) with bearings (12a, 12b; 53a, 53b). The drive and guide mechanism (33-41) and the crank mechanism interact in such a way that, in the front area of the dental arch, i.e. when the corresponding section (31 R) of the guide and drive groove (31) is in operation, the rotary frame (11) turns around the front journal pin (51) of the crank (50), and in the side areas, when guided by the straight sections (31S) of the drive and guide groove (31), the rotary frame (11) simula- taneouslyturns around both journal pins (13, 51) of the crank mechanism (13, 50, 51).
Patent FI-74276-B (FI)
Inventor: MANNONEN MATTI TAPANI
IPC: C07D223/22
Filed: 1986-03-14
Granted: 1987-09-30
Abstract: The invention refers to a new process for the preparation of a valuable intermediate, 5H-Dibenzo-(b, f)-azepine or iminostilbene by catalytic dehydrogenation of lO,ll-Dihydro-5H-dibenzo-(b, f)-azepine or iminodibenzyl in liquid phase in one step in the presence of hydrogen acceptor. Dimethylaniline or diphenylether may be used as a solvent and as catalyst, nobel metal catalysts, such as platinum or palladium on activated carbon or metaloxide catalysts, such as Fe2O3 may be used in the dehydrogenation reaction. Nitrotoluenes, dimethylmaleate or tetrachlorobenzochinone may be used as hydrogen acceptors. The yield of iminostilbene is 77-82 DEG C of the theoretical.