Patent SG-11201811435P-A (SG)
Title: Automated cell processing systems and methods
Inventor: AHLFORS JAN-ERIC
IPC: B01L1/04
Filed: 2017-06-20
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 28 December 2017 (28.12.2017) WIPO I PCT omit VIII Holm o III om OH OH 0l 0111 IIII 111110lII ois (10) International Publication Number WO 2017/221155 Al (51) International Patent Classification: G01N 35/00 (2006.01) BOIL 1/04 (2006.01) BOIL 1/02 (2006.01) G01N 35/10 (2006.01) (21) International Application Number: PCT/IB2017/053674 (22) International Filing Date: 20 June 2017 (20.06.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/352,468 20 June 2016 (20.06.2016) US (71) Applicant: GENESIS TECHNOLOGIES LIMITED [BB/BB]; CGI Tower 2nd Floor, Warrens, St. Michael 22026 (BB). (72) Inventor: AHLFORS, Jan-Eric; 25 rue Les Cedres, Laval, Quebec H7R 1C4 (CA). (74) Agent: YAMAC, Tuba; 2500-1100 Rene-Levesque Blvd West, Montreal, Quebec H3B 5C9 (CA). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (54) Title: AUTOMATED CELL PROCESSING SYSTEMS AND METHODS FIG. 1C (57) : There are provided systems and methods for automated cell processing of biological samples, such as cells for use in cell therapy and regenerative medicine. Systems for automated processing of batches derived from biological samples comprise: a closed and sterile enclosure; a plurality of reagent containers; at least one reagent dispenser; a quality control module for analyzing at least one characteristic of a batch; a harvesting module; a robotic module; and a control unit (CU) communicatively coupled to the at least one reagent dispenser, the quality control module, the harvesting module and the robotic module for controlling the automatic processing of batches. The automatic processing may be executable without handling by a human operator. The system may be configured to N automatically process the plurality of batches without cross-contamination between batches, e.g., under GMP conditions. O C [Continued on next page] WO 2017/221155 Al 0 111 (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))