baber/WOPTO huggingface dataset:
Patent EC-SP11010877-A (EC)
Title: Combinación de inhibidor de la proteasa ns3 de hcv con interferón y ribavirina
Inventor: HUANG DAVID
Filed: 2011-03-09
Abstract: La presente invención se refiere a combinaciones terapéuticas que comprenden (a) Compuesto (1), o una sal farmacéuticamente aceptable del mismo, tal como se describe en el presente documento, (b) un interferón alfa y (c) ribavirina. El Compuesto (1) es un inhibidor selectivo y potente de la proteasa de serina NS3 de HCV. La presente invención se refiere también a métodos para emplear tales combinaciones terapéuticas para el tratamiento de infección por HCV o para aliviar uno o más síntomas de la misma en un paciente.
Patent EC-SP13012362-A (EC)
Title: Derivados de indolizina, su procedimiento de preparación
Inventor: LASSALLE GILBERT
IPC: C07D471/04
Filed: 2013-01-02
Abstract: La invención se refiere a compuestos que responden a la fórmula (I):en la que:- R3 y R4 forman conjuntamente, con los átomos de carbono del núcleo fenilo al que están unidos, un heterociclo nitrogenado de 6 eslabones que responde a una de las fórmulas (A), (B) o (C) siguientes:en las que los trazos ondulados representan el núcleo fenilo al que están unidos R3 y R4.Procedimiento de preparación y aplicación en terapéutica.
Patent EC-SP13013040-A (EC)
Title: 4-aril-n-fenil-1,3,5-triazin-2-aminas que contienen un grupo sulfoximina
Inventor: SIEMEISTER GERHARD
IPC: C07D417/12
Filed: 2013-11-22
Abstract: 4-aril-N-fenil-1,3,5-triazin-2-aminas que contienen un grupo sulfoximina y que presentan la fórmula general (I) o (Ia). Métodos para prepararlas. Su uso en el tratamiento y/o la profilaxis de diversos trastornos, particularmente de los trastornos hiperproliferativos, de las enfermedades infecciosas inducidas por virus y/o de las enfermedades cardiovasculares. Compuestos intermediarios útiles para preparar los compuestos de la fórmula general (I) o (Ia).
Patent EE-200200337-A (EE)
Inventor: BROWN WILLIAM
IPC: C07D405/12
Filed: 2000-12-15
Abstract: The present application is directed to compounds having the general formula:and to the use of these compounds in therapeutic methods.
Patent GB-189706832-A (GB)
Title: A Toy Pipe.
Inventor: CLOCHE GEORGE FRANCIS LA
Filed: 1897-03-16
Granted: 1897-06-19
Abstract: 6832. La Cloche, G. F., and Deans, C. S. March 16. Toy tobacco pipes.-The pipe, to exterior appearance an ordinary wooden or other pipe having a lid over the bowl, is provided within the stem with a squeaker, and in the bottom of the bowl with a thin rubber bladder secured to the stem, above which rests a card carrying a doll's head representing a nigger. The lid is attached by an elastic to the bottom of the bowl, whereby the former is normally kept down. On blowing down the pipe stem, the squeaker is sounded, the bladder is inflated, and the lid forced open by the rising doll's head, which is then rendered visible. When the blowing is stopped, the bladder deflates, the doll's head re-enters the bowl, and the lid closes.
Patent GB-189713027-A (GB)
Title: A Novel or Improved Securing or Holdfast Device adapted for Hats, Walking Sticks, Umbrellas and other articles.
Inventor: REDPATH JOHN
Filed: 1897-05-27
Granted: 1898-04-23
Abstract: 13,027. Redpath, J., and Kerr, C. M. May 27. Hat, umbrella, &c. holders.-A clip for holding hats, umbrellas, walking-sticks. &c. on shipboard or in places of worship, theatres, or other public places, or on chairs, pews, &c., consists of a single or double spring clip a, Fig. 4, secured to a fixed support, each clip being drawn back by a finger-piece a<2> to allow the article to be inserted. Or the clips may be hinged together and controlled by a coiled spring on the pivot. Or two or more prongs e, Fig. 8, may be formed on a spring- retracted stem f, which is drawn out through a casing g to allow the article to be inserted.
Patent GB-189713442-A (GB)
Title: Improvements in Non-return or Lift Valves.
Inventor: SMITH ROBERT BRUCE
Filed: 1897-06-01
Granted: 1898-05-28
Abstract: 13,442. Smith, R. B. June 1. Pump valves.-Non-return valves for use with pumps and for similar purposes are made of a number of metallic sheets d and laminµ e of rubber or other soft material so that the valve works in connection with its seat a without noise and jar. The valve is guided by a stem c fixed to the seat and carrying a guard plate b. Fig. 1 shows the valve composed of two metal plates separated by a layer of soft material. Fig. 3 shows a corrugated metal plate enclosed in two laminµ of soft material. In other modifications, in which a metal plate is enclosed in two laminµ of soft material, the metal plate may be whole or perforated, and may be provided with two flanges around its central apertures. In one case, the upper coating of the metal plate is not in one piece, but in parts which are connected with the lower coating through the perforations in the said metal plate.
Patent GB-189714604-A (GB)
Title: Improvements in or connected with Ploughs.
Inventor: SLEEP WILLIAM HENRY
Filed: 1897-06-16
Granted: 1898-05-07
Abstract: 14,604. Sleep, W. H., and Sleep, R. H. June 16. Ploughs.-Relates to a plough in which the coulter extends upwards from the share and forms a continuation thereof. The share is made in two parts, namely, a point f and a wing g, and the coulter is also made in two parts, namely, the lower part i and an upper part h. The plough body a is shaped to enable the parts to be secured to it, and also to provide clearance spaces in the working of the plough. The Specification describes in detail how the various parts forming the share and coulter are attached to the plough body.
Patent GB-189719857-A (GB)
Title: Improvements in or appertaining to Apparatus applicable for Separating Dust or like Particles from Air or other Gases, also for Separating Dust from Cotton and for other purposes.
Inventor: SUTCLIFFE WILLIAM
Filed: 1897-08-28
Granted: 1898-08-20
Abstract: 19,857. Sutcliffe, W. Aug. 28. Openers and cleaners. - Relates to apparatus of the tornado type, for separating dust from air, such as is described in Specifications No. 20,030, A.D. 1889, N 0.1811, A.D.1891, and Nos. 21,218, 21,731, and 22,919, A.D. 1892. It is described as a double machine applied to the cleaning of cotton fibre. The upper part of the chambers A<1> is cylindrical and the lower part A prismatic ; the cotton and air enter by pipes B, B<1> arranged as shown in Fig. 2 through an opening extending from R to S. The dusty cotton is thrown against the sides of the chamber A' by centrifugal action, and, falling, the dust drops through the perforated floor, while the cotton is guided to the centre of the apparatus by volute ribs J, with flanges that break up the lumps of cotton and liberate the dust. The cotton falls down an axial pipe. A bush L beneath the perforated floor cleans it, and scrapers M guide the dust to a discharge hole O. The air escapes through a perforated metal and gauze or silk filtering-screen C, the lower part D of which carries vanes E that enable the air currents enterirg through B to rotate it. It is cleaned as it rotates by stationary brushes G, H. Rotary brushes G may be driven by the fan when D is stationary. Air may be drawn through the machine from the neighbourhood of a chaff-cutter, and from the discharge pipe thereof, through pipes which are provided with valves, and which may enter the machine on opposite sides or together. The dustladen air may pass through a settling-chamber before it enters the separator. The apparatus may also be used to recover the wool from the dust-laden air drawn from the neighbourhood of woolsorters' tables.
Patent GB-189719866-A (GB)
Title: Improvements in Posts or Supports for Lawn Tennis Nets and the like, and parts connected therewith.
Inventor: AYRES FREDERICK HENRY
Filed: 1897-08-28
Granted: 1898-08-06
Abstract: 19,866. Ayres, F. H., and Thorne, W. G. Aug. 28. Net supports.- Relates to apparatus for supporting and adjusting the tension upon the cords of lawntennis and like nets. The supporting-post A is formed hollow, and of any suitable material. At its top it has a cap a supporting a pulley a<3>, around which passes the straining-cord a<4>, which is secured to the post at a<6>. Within the post is a screwed stem b<2> which can be raised and lowered by an external handle b<11> and bevel gearing b<9>, b<8>, so as to raise and lower a tension pulley b or its equivalent, beneath which the cord passes, and by which the cord is effectually pulled taut. The stem is prevented from turning by a notched plate b<3> thereon, sliding up and down a feather b<5> on a plate b<4>. To the plate b<4> is also fixed a retaining- disc d<7>, through a screwed hole in which the stem b' passes, and which forms an abutment for the bevel-wheel b<8>. To keep out rain &c. a covering plate a<7> is hinged to the cap a.
Patent GB-189720398-A (GB)
Title: An Improved Electric Meter for Alternating and Continuous Currents.
Inventor: BLONDLOT PROSPER RENE
Filed: 1897-09-04
Granted: 1898-07-16
Abstract: 20,398. Blondlot, P. R. Sept. 4. Quantity meters for continuous or alternating currents. The current to be measured passes through fixed and movable coils A, B<1> in series, by cups g of mercury covered with glycerine, the movable coil being supported o n a point o. The current turns the movable coil into the plane of the fixed one, as shown, s u c h movement being assisted when the movable coil is near this neutral position by an iron pin on an arm of it, L, approach ing a stationary bar-magnet, not shown. In the neutral position, another arm c makes contact with a spring R, closing the exciting-circuit of an electromagnet E. Normally a spring-supported armature D presses the spring R against a fixed support, but when the contact is made, the armature is withdrawn by the electromagnet, freeing the spring R, which acting on the arm c causes the movable coil to oscillate. At the same time, a pawl on the armature D moves a ratchet-wheel and counter a step. During the passage of current the movable coil thus oscillates continually, the time of each oscillation varying inversely as the current-strength. The effect of the bar-magnet is to ensure that the spring R acts so that the coil B<1> is thrown to a position from which even a weak current can return it. Other devices for this purpose are referred to in the Provisional Specification.
Patent GB-189721618-A (GB)
Title: Improvements in or connected with Cycles.
Inventor: FERRIS GEORGE ROBERT
Filed: 1897-09-21
Granted: 1898-01-08
Abstract: 21,618. Ferris, G. R. Sept. 21. Luggage-carriers; saddles and seats; passengers, for conveying.-An extra handle-bar and fork 1<1> are mounted upon the spindle 7 of the front wheel of a bicycle, tricycle, &c., and are braced to the ordinary handle pillar 1 by collars 2, 2<1>, bolts 3, and tubes or rods 4, so as to turn with the front wheel. Upon the rods 4 is clamped a platform, luggage-carrier, seat, or saddle 10, preferably formed of two pieces of wood, hinged together at the middle, and padded to form a seat. The platform may be connected with the bolt 3 to prevent it from moving.
Patent GB-189721881-A (GB)
Title: Improvements in Closing Bottles and Jars.
Inventor: COBBOLD CHARLES HERBERT
Filed: 1897-09-24
Granted: 1898-07-30
Abstract: 21,881. Cobbold, C. H., and Brooke, W. Sept. 24. Stoppers.-Relates to stoppering bottles or jars used for preserving milk, fruit, soup, &c. The neck of the bottle &c. is formed with a recess for the rubber or other suitable washer B, and is closed by the stopper A, preferably of glass. A spring clip C is employed to hold the stopper in position during the process of heating, or of extracting the air from the vessel. After cooling &c., the strip may be removed, the stopper being then held in position by the atmospheric pressure, or it may be left as an additional security.
Patent GB-189723058-A (GB)
Title: Improvements in Petroleum Burners.
Inventor: HABERMANN MAX
Filed: 1897-10-07
Granted: 1897-11-13
Abstract: 23,058. Habermann, M. Oct. 7. Lighting oil lamps.-A small secondary burner e is so arranged within the main burner h that it may be employed either as a pilot burner to ignite the main burner, or as a night lamp. The secondary burner l is connected at its lower end g to a rack d, which is operated from the wick-raising mechanism k. When the main wick is raised, the secondary burner is lowered into the guide - tube c and extinguished after having ignited the main wick; when the main wick is lowered, the secondary burner is raised and re-lit before the main flame is extinguished.
Patent GB-189729552-A (GB)
Title: Improvements in Automatic Safety Doors and Gates for Hoists and Lifts.
Inventor: MITCHELL WALTER
Filed: 1897-12-14
Granted: 1898-11-05
Abstract: 29,552. Mitchell, W., and Mitchell, H. Dec. 14. Lifts, well doors for. The door A, made to slide in vertical guides A<3>, is balanced, or nearly so, by a weight B sliding in guides B<3>. As the cage rises, a hinged pawl D<2> on if strikes an arm A<6> on the door and thus raises the latter until it enters an inclined part A<7> of the guide, which causes a disengagement. In the meantime, however, a pawl E has risen above a projection B<4> on the weight to prevent the door from falling again until the cage leaves the landing. Should the cage descend, disengagement between E and B<4> is effected by the entry of the weight B into an inclined part B<5> of the guide B<3>. In a modification, the projection on the door and weight is replaced by a pivoted catch.
Patent GB-189801220-A (GB)
Title: Improved Fastener or Clasp for Shoes, Boots and the like.
Inventor: GROTE CHARLES FREDERICK
Filed: 1898-01-15
Granted: 1898-11-12
Abstract: 1220. Grote, C. F. Jan. 15. Clasp fastenings for boots, shoes, &c. The boot or other article is provided with one or more clasps consisting of a curved metal frame A to the ends a, a<1> of which curved links B, B<1> are hinged or pivoted. The links are attached to the boot or shoe by folded leather pieces C. Fig. 2 shows an under plan of the fastening when secured ; when released the links are spread outwards.
Patent GB-189805059-A (GB)
Title: A New or Improved Nail Puller.
Inventor: NAFEW SAMUEL
Filed: 1898-03-01
Granted: 1898-04-02
Abstract: 5059. Nafew, S. March 1. Nail-extractors.- The nail is gripped between the jaws 7, 8, of which the jaw 7 is fixed to the vertically - sliding bar 6 and the jaw 8 is pivoted thereto and formed with an arm 10. A bar C is pivoted to the arm 10 and to links 12 pivoted to the frame. A ram D slides on the bar C. The ram is first operated in the position shown in Fig. 2, to force the jaws on each side of the nail, and the bar C is then pulled back ; this first closes the jaws and then raises them to the position shown in Fig. 4.
Patent GB-189807448-A (GB)
Title: Improvements in Water Indicators and Alarms for Steam Boilers.
Inventor: STEIGERT LEOPOLD
Filed: 1898-03-28
Granted: 1898-09-17
Abstract: 7448. Steigert, L., and Keck, P. A. March 28. Water-level indicators and alarms.-The chamber A, in steam and water communication with the boiler, is provided with the float B, the spindle D of which passing through a stuffing-box operates a lever pivoted at b. The latter by its deflection operates the valve of one of the whistles d. To drain the float of internal moisture, the ball is fitted with a curved extension of the hollow arm C which communicates by the hollow spindle D with the atmosphere. On the heating of the ball, the moisture is ejected as steam. Instead of whistles, electric bells may be employed.
Patent GB-189808552-A (GB)
Title: Appliance for Enabling the Suspended Vehicles of Elevated Railways to Retain their Vertical Position on Inclines without Assuming an Oscillating Motion.
Inventor: ERBEN EUGEN LANGENS
Filed: 1898-04-12
Granted: 1898-06-04
Abstract: 8552. Abel, C. D., [Langen's Erben, E.]. April 12. Vibration, preventing; vehicles for elevated railways.-The cars A', A<2> are suspended by swivel bolts G<1>, G<2> from the bearer T, which is hung by brackets B<1>, B<2> from the wheels R', R<2> running on the girder F. When the train ascends an incline, the cars swing from the positions shown in Fig. 1 to those shown in Fig. 2. Vibration is prevented by linking all the cars by a rod S to the piston-rod K of a dash-pot C on the locomotive L.
Patent GB-189809770-A (GB)
Title: Adjustable and Reversible Splint.
Inventor: BOYD JOHN
Filed: 1898-04-28
Granted: 1898-06-25
Abstract: 9770. Boyd, J. April 28. Splints; extension apparatus.-An adjustable and reversible splint is composed of a number of sections A<1>, A<2>, A<3>, A<4> connected together by set - screws b<1> entering holes a<5> in their adjacent ends and fitted with semicircular spring bands E for holding the sections in place. The top section A' is furnished with an extension A, which is attached to a steel band or brace B having a pelvic belt C and a perineal strap D. To enable the knee sections A<2> and A<3> to be set at an angle to each other, one of them is formed with a lateral extension a<6> with holes a<7> for receiving one of the set-screws b<1>. All the sections are provided with broad leather straps F having fasteners f<1> for securing the splint to the limb. To the lowest section is adjustably secured a foot-piece G, capable of being adjusted by a screw bolt L moving in a cross-piece K, by which means the limb can be extended.
Patent GB-189810503-A (GB)
Title: Improvements in Steam Turbines.
Inventor: SCHULZ RICHARD
Filed: 1898-05-07
Granted: 1899-02-25
Abstract: 10,503. Schulz, R. May 7. Steam &c. turbines.-Relates to reversible turbines, in which steam is used expansively, each consisting of a number of turbine rings b, c arranged concentrically as shown in Fig. 1, or on the frustum of a cone as shown in Fig. 6. Vanes T' are provided for reversing the engine. Steam, air, or gas entering by the inlet a acts first on the vanes b, and is directed on to the next rung of vanes by guides g in the casing G, and so on, finally passing from the vanes c to the exhaust d. The communication between the pipes V and R and the supply pipe is controlled by a cock X. In the form shown in Fig. 1, the steam &c. passes through the turbine-wheel T alternately in opposite directions, whereby a balancing effect is obtained ; two such turbine-wheels may be secured to the same shaft, and may be situated in one casing and separated by guide-passages, or may have separate casings. In an outward-flow turbine, concentric series of vanes may be arranged on one side of the turbine-wheel for motion in one direction, and vanes for reversing arranged on the other side of the wheel The form of turbine shown in Fig. 6 has an end-thrust, but this may be balanced by the thrust of the propeller, in applying the engine to ships, or by fixing two turbines on the same shaft.
Patent GB-189815197-A (GB)
Title: Improvements in Musical Drums.
Inventor: MILLS BENJAMIN JOSEPH BARNARD
Filed: 1898-07-11
Granted: 1899-04-29
Abstract: 15,197. Mills, B. J. B., [Osmanek, A.]. July 11. Drums.-The snares c, which are arranged inside each of the heads a and a', pass over staples c' and are secured together by a spiral spring d' which distributes the tension. The lower ones are fastened to a ring f while the upper ones pass over a hook f<2>, the shank f of which is flat, to prevent it from turning, and is screw-threaded. The hook can be operated by a wheel f<3>, which forms a nut, and the snares may thus be strained to any required degree.
Patent GB-189819213-A (GB)
Title: Pneumatic Tobacco Pipe Cleaner.
Inventor: PYKE FREDERICK ARTHUR
Filed: 1898-09-09
Granted: 1899-07-29
Abstract: 19,213. Pyke, F. A. Sept. 9. Tobacco-pipe cleaners.-Air is forced through the pipe by an ordinary inflator pump or other means for supplying air under pressure. The nipple d<1> of the pump d is provided with a nozzle e on which is a rubber or other plug a for fixing in the pipe bowl b. The plug a may be applied directly to the nipple d<1>. An arm &c, projecting from the pump may be provided for holding the pipe on the plug a.
Patent GB-189820660-A (GB)
Title: Improvements in the Production of Slides for Optical Lanterns.
Inventor: ERRERA LEO
Filed: 1898-09-30
Granted: 1899-08-05
Abstract: 20,660. Errera, L. Sept. 30. Producing magic - lantern slides by photomechanical printing. The image is printed with transparent ink on a transparent flexible support formed of celluloid, gelatine, collodion, mica, specially-prepared glass, &c. For showing the natural colours, separate blocks are prepared from separate negatives taken through intercepting screens and solutions on plates sensitive to certain rays only, and the prints are made successively in the required colours with transparent inks.
Patent GB-189823530-A (GB)
Title: Improvements in a Method and Apparatus for Generating and Distributing Electric Energy.
Filed: 1898-11-08
Granted: 1899-02-04
Abstract: 23,530. British Thomson-Houston Co., [Green, C. M.]. Nov. 8. Armatures; dynamos, regulating.-A multipolar generator is provided with a closed-coil armature C, the windings of which are divided into sections, connected to separate commutators D, E, and corresponding to pairs of field-magnet poles A, A<1>, B, B<1>. In the arrangement shown diagrammatically, the windings are in two sections, separated on a diameter x by additional insulation, and opposite pairs of commutator segments are connected together. The sections are connected in series with the loads, which are divided into a corresponding number of parts, each connected between two sections of the armature. The field winding is also included in the series, and switches are provided for short-circuiting it or parts of the load. The current generated may be kept constant by an ordinary automatic regulator shifting the brushes round the commutators.
Patent GB-189900505-A (GB)
Title: Improvements in Reciprocating Car Engines.
Inventor: MCINTYRE JOHN
Filed: 1899-01-09
Granted: 1899-02-18
Abstract: 505. McIntyre, J. Jan. 9. Propelling by steam engines. Relates to the arrangement of reciprocating motors within a small compass on and between adjacent car axles on a frame between the sides of the truck frame. Fig. 1 shows in side elevation an engine with one cylinder ; a modification with two cylinders is also shown in the Specification. The cylinder C is carried on a frame A supported on suitable springs on axlebars A<1> on adjacent axles B, B<1>. Motion is communicated to the crank shaft J<1> by a return connecting-rod I reciprocated by a rocking lever H linked to the crosshead E. The engine crank shaft is supported in bearings suspended from the frame A by links K, and is also linked to the axle B by links K'. The links K<1> may be extended and supported by a box K<3> and springs. On the engine crank shaft is a toothed wheel L gearing with a similar wheel on the axle B. Any suitable valve gear may be used, for working which a shaft N may be provided. In the two-cylinder example, two rocking levers H engaging with slotted crossheads are employed, and the two crank shafts are coupled.
Patent GB-189905009-A (GB)
Title: Improvements in Stoppers for Bottles or other Vessels.
Inventor: ANDREWS ARTHUR
Filed: 1899-03-07
Granted: 1899-08-05
Abstract: 5009. Andrews, A. March 7. Stoppers.-The stem a of the stopper is tapered, as shown, and the rubber or other extensible washer c can be expanded on the stem to fit the neck of the vessel. The surfaces of the washer &c. may be corrugated to increase the grip. The enlargement d of the stem a ensures the withdrawal of the washer with the stopper.