baber/WOPTO huggingface dataset:
Patent DE-69616825-D1 (DE)
Title: Triazolone als apolipoprotein-b synthese ihibitoren
Inventor: HEERES JAN
IPC: A61K31/495
Filed: 1996-04-12
Granted: 2001-12-13
Abstract: The present invention concerns novel compounds of formula (I).wherein R1 is C1-10alkyl, C3-7cycloalkyl or C1-6alkyl substituted with C3-7cycloalkyl; R2 is hydrogen or C1-6alkyl; Alk represents C1-3alkanediyl; -A- represents a bivalent radical of formula -CH=CH-N=CH- (a), -N=CH-N=CH- (b), -CH=N-N=CH- (c), -CH=CH-CH=N- (d); in said bivalent radicals a hydrogen atom may be replaced by C1-6alkyl; and Ar is unsubstituted phenyl; phenyl substituted with up to two substituents selected from halo, C1-6alkyl or C1-6alkyloxy; unsubstituted naphthyl; or naphthyl substituted with up to two substituents selected from halo, C1-6alkyl or C1-6alkyloxy; the stereochemically isomeric forms thereof, and the pharmaceutically acceptable acid addition salts thereof. The present invention further comprises the pharmaceutical compositions comprising compounds of formula (I), the preparation thereof as well as the use as a medicine in the treatment of hyperlipidemia.
Patent DE-69622541-D1 (DE)
Inventor: TAKESAKO KAZUTOH
IPC: C12P1/00
Filed: 1996-03-08
Granted: 2002-08-29
Abstract: Novel antibiotics useful as a remedy for fungal infections and a process for producing antibiotic TKR1912-I or pharmacologically acceptable salts thereof, which substances have such physicochemical properties that (1) the mass spectrum thereof according to FAB-MS has a peak of m/z of 559 ÄM+HÜ<+>; (2) the molecule bears 26 carbon atoms and no nitrogen atom; (3) the ultraviolet absorption spectrum thereof in methanol shows a terminal absorptions; (4) the main absorption wavenumbers of the infrared absorption spectrum according to the KBr method are 3430, 2920, 2850, 1740, and 1190 cm<-1>; and (5) they are soluble in methanol, chloroform, and water, but are sparingly soluble in hexane.
Patent DE-69625895-D1 (DE)
Inventor: EPSTEIN J
IPC: H05B33/12
Filed: 1996-02-29
Granted: 2003-02-27
Abstract: Light emitting bipolar devices consist of an electroluminescent organic light emitting material sandwiched between two layers of insulating material each of which is in contact with an electrode. The devices operate with AC voltage at voltages of less than twenty four volts and in some instances at less than five volts. Under AC driving, the device produces modulated light output that can be frequency or amplitude modulated. Under DC driving, the device operates in both forward and reverse bias.
Patent DE-69629145-D1 (DE)
Inventor: BRIGGS RODNEY L
IPC: C08G71/04
Filed: 1996-04-15
Granted: 2003-08-28
Abstract: A curable coating composition is described comprising two components that are reactive with one another upon curing to form urethane linkages. The composition further comprises a third component that includes one or more epoxide groups. Coatings prepared with this coating composition can be cured and coated with additional coating(s), providing good intercoat adhesion to the subsequent coating.
Patent DE-69631483-D1 (DE)
Inventor: BABON JEFF
IPC: C12Q1/68
Filed: 1996-08-30
Granted: 2004-03-11
Abstract: Disclosed is a method for detecting one or more mismatches between a first and a second nucleic acid, the first and second nucleic acids being capable of preferentially hybridizing. The method involves: a) providing the first nucleic acid in its single-stranded form, the first nucleic acid being bound to the first member of a specific binding pair; b) providing the second nucleic acid in its single-stranded form, the second nucleic acid being bound to a detectably labelled reagent; c) contacting the first nucleic acid with the second nucleic acid under conditions allowing heteroduplex formation; d) contacting the product of step (c) with a magnetic bead to which is bound the second member of the specific binding pair under conditions allowing complex formation between the first and the second members of the specific binding pair; e) applying a magnetic field to the mixture to facilitate separation of the magnetic bead from the remainder of the product of step (c); f) contacting the magnetic bead-bound nucleic acid with a resolvase capable of recognizing at least one single base pair mismatch in a heteroduplex, under conditions which permit the resolvase to cleave the heteroduplex; and f) analyzing the product of step (f), the presence of a cleavage product being an indication of a mismatch between the first and second nucleic acids.
Patent DE-69632916-D1 (DE)
Inventor: COSFORD NICHOLAS D
IPC: C07D213/61
Filed: 1996-04-04
Granted: 2004-08-19
Abstract: In accordance with the present invention, there is provided a class of pyridine compounds which are modulators of acetylcholine receptors. The compounds of the invention displace acetylcholine receptor ligands from their binding sites. Invention compounds may act as agonists, partial agonists, antagonists or allosteric modulators of acetylcholine receptors, and are useful for a variety of therapeutic applications, such as the treatment of Alzheimer's disease and other disorders involving memory loss and/or dementia (including AIDS dementia); disorders of attention and focus (such as attention deficit disorder); disorders of extrapyramidal motor function such as Parkinson's disease, Huntington's disease, Gilles de la Tourette syndrome and tardive dyskinesia; mood and emotional disorders such as depression, panic, anxiety and psychosis; substance abuse including withdrawal syndromes and substitution therapy; neuroendocrine disorders and dysregulation of food intake, including bulimia and anorexia; disorders of nociception and control of pain; autonomic disorders including dysfunction of gastrointestinal motility and function such as inflammatory bowel disease, irritable bowel syndrome, diarrhea, constipation, gastric acid secretion and ulcers; pheochromocytoma; cardiovascular dysfunction including hypertension and cardia arrhythmias, comedication in surgical procedures, and the like.
Patent DE-69721144-D1 (DE)
Inventor: LAGRANGE GILLES
IPC: C23C16/50
Filed: 1997-07-01
Granted: 2003-05-28
Abstract: The assembly to treat the surface of a moving polymer material, through the electrical discharge of a barrier dielectric in a controlled gas atmosphere, has a data processing unit (10) to take data on the speed of material movement with outputs to send command signals to the control (14) for the gas feed (7) and the electrical supply (8) control (15). They determine the vol. of gas feed (7) and/or level of power supply (8), as a function of the speed of material (3) travel through the assembly (2), to match the processing action to the movement speed. Also claimed is an operation where the speed of substrate travel is measured through the assembly. The control system sets the vol. of gas delivered (7) and/or the power level of the electrical supply (8) according to the measured substrate speed. Preferably The data processing unit (10) outputs are linked to the controls (18,19) for gas extraction (9), to set the extraction rate in relation to the speed of substrate (3) travel. The gas extraction system has a main exhaust (16) at the entry into the assembly (2) and a second exhaust (17) is at the assembly outlet. The data processing unit (10) is linked to the controls (18, 19) for both exhausts. The data processing unit (10) can simulate and/or use a model for the operation of the assembly (2) to set the parameters for the surface treatment of the substrate (3) passing through, for a given effect at the outlet. The unit (10) is linked to a remote control unit by data links (20). The unit (10) has at least one interface (21, 22) for a manual input.
Patent DE-69724062-D1 (DE)
Inventor: HAUSER KENNETH LEE
IPC: A61K31/535
Filed: 1997-09-22
Granted: 2003-09-18
Abstract: The invention provides benzothiophene compounds, formulations, and methods of inhibiting bone loss or bone resorption, particularly osteoporosis, and cardiovascular-related pathological conditions, including hyperlipidemia, and other cardiovascular pathologies.
Patent DE-69728152-D1 (DE)
Title: Hoch-lipophile campothecin-derivate
Inventor: HAUSHEER HERMAN
IPC: C07D515/00
Filed: 1997-08-15
Granted: 2004-04-22
Abstract: Novel compounds, formulations and methods of treating patients with cancer are provided for in this invention. The compounds are derivatives of camptothecin, and specifically relate to compounds having novel substitutions at the C-7 position of the camptothecin scaffold B-ring. The formula I compounds are highly lipophilic, lactone stable, do not require metabolic activation, and are potent antineoplastic compounds.
Patent DE-69735738-D1 (DE)
Inventor: BADOZ JEAN-MARIE
IPC: A61C5/02
Filed: 1997-04-01
Granted: 2006-06-01
Abstract: The reamer includes helicoidal flutes having a cutting lip characterised such that the tangent (1) at the point of cut (4) of the instrument tends to superpose with the tangent (2) of the diameter of the circle (6) in which is inscribed a cut section (5) and passing by this point of cut. The tangent at the points of cut of the instrument is merged with the tangent of the diameter of the circle in which is inscribed a cut section of the reamer and passing by the point of cut.
Patent DE-69813025-D1 (DE)
Inventor: SANTTI RISTO
IPC: A61K31/425
Filed: 1998-12-09
Granted: 2003-05-08
Abstract: This invention relates to the use of an aromatase inhibitor in the treatment of decreased androgen to estrogen ration (DATER) as well as to a method for the treatment of detrusor urethral sphincter dyssnergia (DUSD) in men.
Patent DE-69833838-D1 (DE)
Inventor: TURNER CHRISTOPHER GORDON GERV
IPC: G06K17/00
Filed: 1998-08-28
Granted: 2006-05-11
Abstract: A reader arrangement 22 for an electronic identficabion system is disclosed and claimed. The arrangement 22 includes a plurality of reader heads 22.1 to 22.4 for energizing transponders 28. 1 to 28.n to be read, and a controller 29 therefor. The controller 29 switches activation of the reader heads in a multi-phase sequential pattern including a first phase for activating a first set 22.1 and 22.3 of the reader heads and at least one further phase for activating a further set 22.2 and 22.4 of the reader heads. The switching is such that a complete cycle plus at least the first phase of a subsequent cycle is completed within a time period not longer than a reset period of the transponders. The reset period is the period between removal of an energizing signal from a transponder and the transponder re-entering a normal operational mode.
Patent DE-69834272-D1 (DE)
Inventor: NYSTROEM CHRISTER
IPC: A61J3/06
Filed: 1998-10-06
Granted: 2006-05-24
Abstract: The invention has reference to a procedure and a device for the dosing of a medicine to a consumer. In accordance with the invention, a medicine is supplied in the form of a number of small units, partial doses, containing a determined, equal quantity of the active medical substance, and a number of these units, which correspond to a predetermined dose quantity, total dose, of the active medical substance are taken out and dispensed to the consumer. A device for the carrying out of the procedure in accordance with the invention comprises devices (4, 11, 12) for counting and feeding-out of a number of units, partial doses of the medicine, which correspond to a predetermined dose quantity of the active medical substance and for transport (6) of these units to a dispensing device (9) for dispensing of the above-mentioned dose quantity, total dose, to a consumer.
Patent DE-69841927-D1 (DE)
Inventor: GAY JORDAN L
IPC: B62M7/12
Filed: 1998-12-10
Granted: 2010-11-18
Abstract: A vehicle drive assembly with a motor configured for driving the vehicle and including a rotatably driven motor shaft. A first swing arm has a first end housing the motor and a second end pivotably and supportively attachable to a vehicle body, with an elongated portion joining the ends. The vehicle also has a gearbox housing configured for transmitting torque to a road surface through a road engaging member, and a transmission directly engaged with the motor shaft and housed within the gearbox housing. The transmission is configured for transmitting torque from the motor shaft to the housing. A second swing arm is pivotably and supportively attachable to the vehicle body. An axle is fixed to the second swing arm, received within the gearbox housing, and attached to the transmission such that the second swing arm is supported by the transmission. The transmission preferably includes a planetary gear reduction unit with a gear carrier rotationally fixed to the first swing arm and a plurality of gears operatively associated with the shaft and the gearbox housing to transmit torque therebetween. Preferably at least one of the gears is mounted to the gear carrier, more preferably a plurality of planetary gears is mounted to the gear carrier.
Patent DE-69902227-D1 (DE)
Inventor: MASSELUS JEAN-EMMANUEL
IPC: H02H7/12
Filed: 1999-01-26
Granted: 2002-08-29
Abstract: The short-circuit protection operates on one half of the inverter to bring all the inverter phases to either the positive or negative supply potential. The power switches in the inverter (1R,2R,1S,2S,1T,2T) are controlled so that one half of the bridge is closed and the other half is open, stopping the supply to the motor and avoiding a short-circuit across the DC rails of the bridge.
Patent DE-69904046-D1 (DE)
Inventor: CHRISTENSEN HOLM
IPC: A23K1/175
Filed: 1999-05-31
Granted: 2003-01-02
Abstract: A method of obtaining optimum performance of piglets without the use of antibiotic growth promoters, comprising administering to the piglets at least during the entire suckling period two different feed supplement compositions comprising dietary fibres, iron and other micronutrients including copper and zinc, where the first composition has the highest content of iron. A third feed supplement composition comprising dietary fibres and electrolytes may be used to prevent or cure diarrhoea as a substitute for antibiotic treatment.
Patent DE-69908113-D1 (DE)
Inventor: PALLESCHI VINCENZO
IPC: G01N21/71
Filed: 1999-03-18
Granted: 2003-06-26
Abstract: A method based on the LIBS technique is described, which allows to determine, without calibration of the measurement system, the concentration of atomic components in solid, liquid and aerial samples. The method comprises: (a) obtaining the plasma temperature (T) of at least one species of the emitted radiation; (b) determining the partition function U (T) of each species of the emitted radiation at the plasma temperature; (c) calculating the concentration value of each species once deducted an experimental factor (F); (d) calculating the concentration value of each non-individuated species by Saha equation; (e) calculating the concentration of atomic components as sum of the corresponding species concentrations; (f) measurement of the concentration of components by eliminating the experimental factor through normalization.
Patent DE-69909651-D1 (DE)
Inventor: JEGANATHAN GOWPER
IPC: C07C69/732
Filed: 1999-12-16
Granted: 2003-08-21
Abstract: New compounds of the formula Iare described, whereinn is >1;X is O or NR4;L is a n-valent linking group defined in claim 1 andR1 is H, halogen, C1-C25-alkyl, C3-C25-alkenyl, unsubstituted or by C1-C4-alkyl substituted C5-C8-cycloalkyl;R2 and R3 independently of each other are C1-C4-alkyl, or together with the carbon atom they are bonded to, form a carbocyclic C5-C7 ring, especially C5-C7 cycloalkylene; andm is 1-20, especially 2-4.Compounds of the formula I are active as Dox-scavengers in color photographic material.
Patent DE-69910559-D1 (DE)
Inventor: BERGE ROLF
IPC: A23L33/20
Filed: 1999-04-23
Granted: 2003-09-25
Abstract: The present invention relates to novel fatty acid analogous of the general formula I:         CH<sub>3</sub> -[CH<sub>2</sub>]<sub>m</sub> - [x<sub>i</sub> - CH<sub>2</sub>]<sub>n</sub> - COOR,as defined in the specification, which can be used for the treatment and/or prevention of hypertension.
Patent DE-69922355-D1 (DE)
Inventor: WARDLAW STEPHEN C
IPC: G01N33/49
Filed: 1999-02-19
Granted: 2005-01-05
Abstract: Formed constituents of a quiescent anticoagulated whole blood sample are optically or visually analyzed in a sample chamber which has a varying through plane thickness due to convergent opposing sample chamber walls. At least one of the convergent walls of the chamber is transparent so that the blood sample constituents can be observed. The chamber's varying thickness produces a first lesser thickness region in the chamber wherein a quiescent monolayer of red blood cells in the sample will reside after the sample is introduced into and fills the chamber. Larger formed constituents such as white blood cells in the sample are unable to enter the aforesaid lesser thickness region of the chamber. The red cells which reside in the greater thickness regions will agglomerate to form rouleaux and lacunea. The exact thickness of the chamber at any particular location in the chamber can be predetermined, or can be determined in situ as the sample is being analyzed. By admixing certain dyes with the blood sample, various characteristics and other information can be derived from the various formed constituents in the sample by means of a scanning instrument which is able to measure various color and other signals emitted from the sample at various locations within the chamber, or by means of visual examination of the sample in the chamber. The thickness of the lacunae areas of the sample can be calculated by the instrument as a function of signal emission strength from the dyes or stains. The emissions can be the result of sample fluorescence or can be the result of signal density through the sample. Particle volumes can be measured as a function of signal emission suppression caused by the particles. Erythrocyte sedimentation rates (ESR) can also be derived from a blood sample disposed in the sampling chamber.
Patent DE-69923615-D1 (DE)
Inventor: TARREGA LLORET MIGUEL ANGEL
IPC: E05D15/06
Filed: 1999-03-05
Granted: 2005-03-17
Abstract: Mechanism for mounting sliding glass doors, consisting of an upper rail (3-4), lower guides (5-6) and suspension heads (7-8) attachable to the upper edge of the door (1-2) and having rolling elements (9-10) which can move along the upper rail. The suspension heads are made from two baseplates which are connected to each other and to the door and which have on their inner face from the upper edge corresponding matching indentations with a longitudinal channel or groove (19) which define guides between which is mounted a baseplate (20) with an orifice for a screw (22) which attaches it to the rolling elements (19). <IMAGE>   <IMAGE>
Patent DE-69924740-D1 (DE)
Inventor: YOO SEO HONG
IPC: A61K8/00
Filed: 1999-07-20
Granted: 2005-05-19
Abstract: Compositions for pharmaceutical and other uses for preparing clear aqueous solutions containing bile acids which do not form precipitates over selected ranges of pH values of the aqueous solution and methods of making such solutions. The compositions of the invention comprise water; a bile acid in the form of a bile acid, bile acid salt, or a bile acid conjugated with an amine by an amide linkage; and a high molecular weight aqueous soluble starch conversion product. The composition remains in solution without forming a precipitate over a range of pH values and, according to one embodiment, remains in solution for all pH values obtainable in an aqueous system. The composition, according to some embodiments, may further contain a pharmaceutical compound in a pharmaceutically effective amount.
Patent DE-69936540-D1 (DE)
Inventor: DYBEDOKKEN BJOERN MAGNE
IPC: H04W4/18
Filed: 1999-12-07
Granted: 2007-08-23
Abstract: The present invention relates to a method for passing information between a local exchange and a user/terminal, the language used for presenting the information being chosen in the terminal and the local exchange, and in order to avoid that messages generated by the terminal and the text generated by the local exchange are presented in different languages the present invention suggest a method to synchronize the language in the terminal and the language of the local exchange, or vice versa, wherein are used predefined codes for each of the languages involved.
Patent DE-69938840-D1 (DE)
Inventor: ROENNEKE HANS
IPC: H04L29/06
Filed: 1999-12-07
Granted: 2008-07-10
Abstract: Per-packet billing for a packet data network, mobile or fixed, is provided by retrieving and processing all packets transported at a physical layer of the network, where the data packets are communicated with a traffic function that operates independently of a billing function. Using a billing-function computing resource, which is separate and independent from a traffic-function computing resource that processes traffic related information, the billing data are filtered out, processed, stored and distributed, without competing with the traffic functions of the network. Two independent physical layer interfaces separately couple a communication link of the physical layer to the billing-function computing resource and traffic-function computing resource, respectively.
Patent DE-69940549-D1 (DE)
Inventor: MOUSSEAU GARY P
IPC: G06F17/30
Filed: 1999-05-28
Granted: 2009-04-23
Abstract: A system and method for pushing information from a host system to a mobile data communication device upon sensing a triggering event is disclosed. A redirector program operating at the host system enables a user to continuously redirect certain user-selected data items from the host system to the user's mobile data communication device upon detecting that one or more user-defined triggering events has occurred. The redirector program operates in connection with event generating applications and repackaging systems at the host system to configure and detect a particular user-defined event, and then to repackage the user-selected data items in an electronic wrapper prior to pushing the data items to the mobile device.
Patent DE-502004002841-D1 (DE)
Inventor: BAUER LOTHAR
IPC: F01P11/02
Filed: 2004-01-28
Abstract: The engine (1) has a crankcase with a crankshaft driving a cooling water pump module (14), which is mounted on the front of the crankcase and has at least one integrated cooling water channel, and a generator via a belt. The cooling water pump module is arranged at a region off transition from the front (15) of the engine to a side wall (16) and the channel has a flow connection to an oil cooler module (19).
Patent DE-502004003191-D1 (DE)
Inventor: KNECHT ANDREAS
IPC: F15B13/00
Filed: 2004-02-23
Abstract: A proportional magnetic valve (1) for the engine block of a combustion engine comprises an electromagnet (2) operating a valve piston which comprises a housing with connection borings for a pressure medium. At least one of the borings lies in a groove (9,10) which extends along the valve. Preferably the valve is a cartridge valve.
Patent DE-502004003681-D1 (DE)
Inventor: SEILER CHRISTIAN
IPC: G06F13/42
Filed: 2004-02-18
Abstract: In a method for transmitting data over a fieldbus of process automation technology with a field device in which a first application program for a first fieldbus protocol runs, the data of a second application program for a second transmission protocol are mapped onto the first fieldbus protocol and transmitted as fieldbus telegrams.