baber/WOPTO huggingface dataset:
Patent NZ-526400-A (NZ)
Title: Novel medicament compositions based on tiotropium salts and on salmeterol salts
Inventor: SCHMELZER CHRISTEL
IPC: A61P11/06
Filed: 2001-11-09
Abstract: A propellant- free inhalable solution containing one or more tiotropium salts combined with one or more salmeterol salts selected from the hydrochloride, hydrobromide, sulphate, phosphate and methanesulphonate, salts, optionally in the form of the enantiomers, mixtures of enantiomers or in the form of the racemates thereof, optionally in the form of the solvates or hydrates and optionally together with a pharmaceutically acceptable excipient; and a solvent selected from water, ethanol and a mixture of water and ethanol, is disclosed. The described inhalable solution may be useful in the preparation of a medicament for the treatment of respiratory diseases, asthma or COPD.
Patent NZ-529461-A (NZ)
Title: Novel indole derivatives
Inventor: ROTTLANDER MARIO
IPC: C07D403/12
Filed: 2002-06-27
Abstract: Disclosed are compounds of formula I, wherein: A is O or S, n is 2-10 m is 2 or 3, W is N, C or CH, Q is N, C or CH, R1 is H, alkyl, alkenyl, alkynyl, cycloalkyl-alkyl, aryl-alkyl or acyl, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of disorders responsive to antagonism of 5-HT1A receptors.
Patent NZ-530507-A (NZ)
Title: Novel anticonvulsant derivative salts
Inventor: ABDEL-MAGID AHMED
IPC: A61P25/08
Filed: 2002-07-03
Abstract: Disclosed are crystalline sodium or potassium salts of topiramate (formula (I)) and processes of forming them wherein the salt of the compound of formula (I) is formed at the sulfamate group. Also disclosed are pharmaceutical compositions containing the above salts.
Patent NZ-534179-A (NZ)
Title: Pharmaceutical compositions comprising 2-(4-ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine in nanoparticulate form
Inventor: APPLEBY JONATHAN
IPC: A61K9/16
Filed: 2003-03-13
Abstract: Disclosed is a pharmaceutical composition of compound (I) in which the compound is present in solid particles in nanoparticulate form in admixture with one or more pharmaceutically acceptable carriers or excipients. The composition may also contain hydroxypropylmethylcellulose (HPMC), mannitol and sodium lauryl sulphate. Also described is process for preparing the composition. The disclosed composition is useful in the treatment of conditions mediated by COX-2.
Patent NZ-534877-A (NZ)
Title: Glutaminyl based DPIV inhibitors
Inventor: DEMUTH HANS-ULRICH
IPC: C07D295/185
Filed: 2002-06-27
Abstract: An acid addition salt of a compound of the formula (I) is disclosed, wherein X = CH2 or S; wherein the acid addition salt is a salt of hydrochloric acid. The pharmaceutically acceptable acid addition salt forms of the compounds of the formula (I) are useful in treating conditions mediated by dipeptidyl peptidase IV (DPIV) or DPIV-like enzymes, such as arthritis, obesity, immune and autoimmune disorders, allograft transplantation, cancer, neuronal disorders and dermal diseases.
Patent NZ-535275-A (NZ)
Title: Spheron components useful in determining compounds capable of treating symptoms of alzheimer's disease, and treatments and animal models produced therefrom
Inventor: AVERBACK PAUL
IPC: A61K38/00
Filed: 2003-03-04
Abstract: The present invention relates to protein components of spherons that are useful for identifying compounds capable of preventing and/or ameliorating symptoms of Alzheimer's Disease and/or dementia associated with cerebral amyloidosis. The invention also relates to the compounds identified by the methods, and methods of treating and/or ameliorating symptoms of Alzheimer's Disease and/or dementia associated with cerebral amyloidosis. The invention also relates to methods of making an Alzheimer's Disease or dementia associated with cerebral amyloidosis animal model or test animal, the animal model produced therefrom, and to a method of using the animal model to screen for effective therapies.
Patent NZ-537356-A (NZ)
Title: Fungicidal combination of trifloxystrobin prothioconazole and fluxastrobin
Inventor: WACHENDORFF-NEUMANN ULRIKE
Filed: 2003-06-11
Abstract: Disclosed herein is a fungicidal combination of active substances, which contains two previously known oxime ether derivatives and a previously known hydroxyethyl-triazol derivative and is very suitable for controlling phytopathogenic fungi. The fungicidal combination particularly comprises a trifloxystrobin of formula (I); a prothioconazole of formula (II); and a fluoxastrobin for formula (III).
Patent NZ-543131-A (NZ)
Title: Magnetic gravity wheel
Inventor: GREEN STEPHEN RANDALL
Filed: 2005-10-21
Abstract: A wheel that rotates under magnetic and gravitational forces is disclosed. A set of discs (d) that have magnets affixed to half their faces (l) are free to rotate on a larger wheel (W) under the influence of external fixed magnets (2)
Patent NZ-548532-A (NZ)
Title: Use of adefovir or tenofovir for inhibiting MMTV-like viruses involved in breast cancer and primary biliary cirrhosis
Inventor: CIHLAR TOMAS
IPC: A61K45/06
Filed: 2005-01-21
Abstract: Disclosed is the use of adefovir or tenovir for preparing a pharmaceutical formulation for the treatment of human biliary cirrhosis.
Patent NZ-567318-A (NZ)
Title: Abrasive alumina particulate material, and method of planarizing a workpiece using the abrasive
Inventor: HAERLE ANDREW G
IPC: C01F7/02
Filed: 2006-10-13
Abstract: Disclosed is an abrasive particulate material comprising: alumina particles comprising transition alumina and at least 5.0wt% and not greater than about 40 wt% of an amorphous phase, the alumina particles having a density not greater than about 3.00g/cm3, a primary particle size not greater than about 85 nm, and a specific surface area of not less than about 100 m2/g. Also disclosed is a method of forming the above material comprising: providing feedstock particles containing principally transition alumina; and milling the feedstock particles to form the above material, wherein milling comprises wet-milling in an acidic solution having a pH of less than 5.0.
Patent NZ-570446-A (NZ)
Title: Toric lenses alignment using pre-operative images
Inventor: BOUKHNY MIKHAIL
IPC: A61B8/10
Filed: 2008-08-12
Abstract: A method to place an intraocular lens (IOL) is provided. The method includes: capturing information associated with an eye in which an IOL is to be implanted; capturing incision location information and induced astigmatism information associated with the eye in which an IOL is to be implanted; providing the information to an IOL calculating software program operable to calculate a location and orientation of the IOL within the eye; and generating a placement guide operable to assist a surgeon in placing the IOL within the eye. The placement guide includes an image of the eye generated based on pre-operative captured information.
Patent NZ-572628-A (NZ)
Title: User interface for monitoring a plurality of faulted circuit indicators
Inventor: SCHWEITZER EDMUND
IPC: G01R15/00
Filed: 2007-05-18
Abstract: A wireless device indicating whether a faulted circuit indicator is connected to a radio interface unit includes a radio interface status indicator corresponding to the radio interface unit and adapted to indicate whether or not the faulted circuit indicator is connected to the radio interface unit.
Patent NZ-574261-A (NZ)
Title: Flow control device that controls fluid flow using disc or body moved by Bernoulli effect
Inventor: AAKRE HAAVARD
IPC: E21B34/08
Filed: 2007-06-13
Abstract: Disclosed is a self-adjustable flow control device (2) for controlling the flow of fluid into a production pipe (1) of a well in a reservoir containing at least one of oil or gas. The device (2) comprises an inlet (10) and one or more outlets. A flow path (11) is formed between the inlet (10) and one or more outlets. The flow control device (2) comprises a movable disc or body (9) that is provided in a recess and held by holding means. The fluid enters the flow control device (2) through the inlet (10) and flows towards and along the disc or body (9) and out through the one or more outlets. The disc or body (9) is arranged to move by a force exploiting the Bernoulli Effect that is created when the disc or body (9) is exposed to a flow of liquid and any stagnation pressure that is created over the disc or body (9). The flow -through area of the flow control device (2) is reduced or increased respectively depending on the composition and the properties of the fluid.
Patent NZ-576488-A (NZ)
Title: Process for the production of recombinant proteins using carnivorous plants
Inventor: BITEAU FLORE
IPC: C12N15/82
Filed: 2007-08-29
Abstract: Provided is a process for producing at least one protein, comprising the cultivation of a carnivorous plant selected from the Drosera and Nepenthes genera, wherein said plant has been genetically modified to express said protein or proteins, and said protein or proteins are collected from the digestive secretions of said carnivorous plant traps.
Patent NZ-577468-A (NZ)
Title: Device and process for improving mixing in the uv disinfection of liquids
Inventor: MEESE WOLF-DIETRICH
IPC: C02F1/32
Filed: 2007-07-12
Abstract: A device for the ultraviolet (UV) disinfection of liquids in an open or closed channel (1). The device has: A. An inflow for the liquid to be disinfected; B. A UV irradiator (2) arranged downstream of the inflow in a main flow direction (9); C. An outflow arranged downstream of the UV irradiator; and D. A mixing device (6) that is driven by an electric motor and is arranged between the inflow and the UV irradiator. The mixing device creates turbulence in the channel by generating a cross-flow (8) having a velocity component transverse to the main flow direction. The mixing device can be a propeller with a nozzle ring arranged at an angle of 90 degrees to the main flow direction.
Patent NZ-578787-A (NZ)
Title: Manufacture of filled paper
Inventor: REINICKE HOLGER
IPC: D21H17/63
Filed: 2008-01-21
Abstract: Disclosed is a process of making filled paper comprising the steps of providing a thick stock cellulosic suspension that contains mechanical pulp and filler, diluting the thick stock suspension to form a thin stock suspension, in which the filler is present in the thin stock suspension in an amount of at least 10% by weight based on dry weight of thin stock suspension, flocculating the thick stock suspension and/or the thin stock using a polymeric retention/drainage system, draining the thin stock suspension on a screen to form a sheet and then drying the sheet in which the polymeric retention/drainage system comprises, i) a water-soluble branched anionic polymer and ii) a water-soluble cationic or amphoteric polymer.
Patent NZ-580623-A (NZ)
Title: Transgenic plants containing soluble cell wall polysaccharides
Inventor: SHOSEYOV ODED
IPC: C12N15/82
Filed: 2008-03-26
Abstract: Disclosed is a transgenic plant expressing cellobiose dehydrogenase (CDH) and a signal peptide which directs expression of the CDH to the plant cell wall. Also disclosed are products containing material from the transgenic plant and methods of making products.
Patent NZ-588647-A (NZ)
Title: Secure internet transactions with secure communication links between two servers for communicating transaction data
Inventor: WISEMAN NICK
IPC: G06Q20/00
Filed: 2009-04-24
Abstract: Disclosed does a method and system for performing an online transaction within a single web session. The method includes performing authentication of a user at a first web server providing a first web page to the user from the first web server, wherein the first web page includes a link to a second web page provided by a second web server. A first communication link between the first web server and the second web server is established for secure transmission of user data from the first web server to the second web server, prior to completion of an online transaction. A second communication link between the first web server and the second web server is established following completion of the transaction, for secure transmission of transaction data between the web servers.
Patent NZ-590569-A (NZ)
Title: Factor viii polymer conjugates
Inventor: TURECEK PETER
IPC: A61K47/48
Filed: 2009-07-29
Abstract: Patent No. 590569 Disclosed is the use of a composition comprising (i) a conjugate comprising a native Factor VIII modified with a water soluble polymer bound thereto, said water soluble polymer attached to the modified Factor VIII via an oxidized carbohydrate moiety, said modified Factor VIII retaining at least 50% of native FVIII activity; and (ii) a pharmaceutically acceptable excipient for the preparation of a medicament for treating a bleeding disorder in a subject in need thereof, wherein said medicament is formulated for administration in an amount effective to treat said bleeding disorder.
Patent NZ-596058-A (NZ)
Title: Influenza hemagglutinin compositions and uses thereof
Inventor: JEGERLEHNER ANDREA
IPC: A61K47/48
Filed: 2010-04-30
Abstract: NZ 596058 Disclosed is a composition comprising: a virus-like particle (VLP) with at least one first attachment site, wherein said virus-like particle is a virus-like particle of an RNA bacteriophage; and at least one antigen with at least one second attachment site, wherein said at least one antigen is a fragment of an ectodomain of an influenza virus hemagglutinin protein, wherein said fragment of said ectodomain of an influenza virus hemagglutinin protein comprises at least 80 contiguous amino acids of said ectodomain of an influenza virus hemagglutinin protein, and wherein said fragment of said ectodomain of an influenza virus hemagglutinin protein is a fragment of the HA1 subunit of said ectodomain of an influenza virus hemagglutinin protein, and wherein said fragment of said ectodomain of an influenza virus hemagglutinin protein comprises at least two and at most four pairs of cysteine residues which are capable of forming intramolecular disulphide bonds; wherein (a) and (b) are linked through said at least one first and said at least one second attachment site.
Patent NZ-601245-A (NZ)
Title: Treatment of laminated radiata pine by lamination with colourless or tinted glue and surface finishing with striations for disguising glue lines
Inventor: GUDSELL DANIEL JON
IPC: B32B21/13
Filed: 2012-07-13
Abstract: A laminated radiata timber product is treated with preservative and is coloured to mimic the colour of a different wood. The timber product is laminated with a colourless or tinted glue and has a surface finishing of striations applied to the surface of the timber so as to disguise glue line(s).
Patent NZ-602170-A (NZ)
Title: Modified leptin polypeptides and their uses
Inventor: KRAYNOV VADIM
IPC: C07H21/04
Filed: 2009-02-05
Abstract: NZ 602170 Disclosed is a leptin polypeptide comprising an amino acid sequence set forth in SEQ ID NO: 2 or SEQ ID NO: 4 as defined in the specification, wherein one or more amino acid(s) selected from amino acids at positions 46, 108 and 111 of SEQ ID NO: 2 or a corresponding amino acid(s) of SEQ ID NO: 4 is/are a non-naturally encoded amino acid (NEAA) by virtue of comprising a fatty acid moiety.
Patent NZ-618085-A (NZ)
Title: Electric machine, synchronous generator-field pole, synchronous generator-rotor comprising a plurality of field poles and method for producing a synchronous generator-field pole of an electric machine
Inventor: JEPSEN TORSTEN
IPC: H02K15/02
Filed: 2012-06-05
Abstract: The invention relates to field pole for a synchronous generator-rotor comprising a plurality of field pole segments (101-106) that are offset in relation to each other and that each have a plurality of identical field pole laminations. Each field pole lamination has a pole shaft (110) with a first centre line (118) and a pole head (120) with a second centre line (128). The first and second centre lines can be different from each other in adjacent pole segments (101-106).
Patent NZ-619172-A (NZ)
Title: Assays for detecting neutralizing autoantibodies to biologic therapy with tnf alpha
Inventor: WANG SHUI LONG
IPC: G01N33/564
Filed: 2012-07-06
Abstract: A method for measuring the level or percent of a neutralizing form of an autoantibody to an anti-TNF-alpha drug in a sample is disclosed. The method comprises (a) contacting the sample with an acid to dissociate preformed complexes of the autoantibody and the anti-TNF-alpha drug; (b) contacting the sample with a labelled anti-TNF-alpha drug and a labelled TNF-alpha following dissociation of the preformed complexes; and (c) neutralizing the acid in the sample to form (i) a first labelled complex of the labelled anti-TNF-alpha drug and the autoantibody; and/or (ii) a second labelled complex of the labelled anti-TNF-alpha drug, the labelled TNF-alpha and the autoantibody; (d) subjecting the first labelled complex and/or the second labelled complex to size exclusion chromatography to separate them from free labelled TNF-alpha, free labelled anti-TNF-alpha drug, and/or a complex of labelled anti-TNF-alpha drug and labelled TNF-alpha; (e) measuring the level of free labelled TNF-alpha after size exclusion chromatography; and (f) comparing the level of free labelled TNF-alpha measured in step (e) to a normalized level or percent of free labelled TNF-alpha in a control sample, where the normalized level or percent of the free labelled TNF-alpha in the control sample corresponds to the level or percent of a neutralizing form of the autoantibody or comparing the level of the free labelled TNF-alpha measured in step (e) to the level of free labelled TNF-alpha in a control sample, thereby detecting the presence of a neutralizing and/or non-neutralizing form of the autoantibody. The above described method is useful for monitoring the formation of neutralizing and/or non-neutralizing anti-drug antibodies over time while a subject is on biologic therapy and determining the cross-reactivity of neutralizing anti-drug antibodies in a subject’s sample with alternative biologic therapies. The above described method provides information for guiding treatment decisions for those subjects receiving therapy with a biologic agent and improves the accuracy of optimizing therapy, reducing toxicity, and/or monitoring the efficacy of therapeutic treatment to biologic therapy.
Patent NZ-621627-A (NZ)
Title: Method for controlling creep in spirally expandable profile
Inventor: WEAVER RON
IPC: F16L55/165
Filed: 2012-08-06
Abstract: An elongated web or strip (200) comprising a wall portion bounded by edge portions and adapted to form a conduit by spirally winding said web and joining adjacent edge portions. The edge portions (210, 220) are adapted to permit relative movement between adjacent portions of the spiral conduit and thereby provide radial alteration of the conduit. The web includes a compensation portion (300) to alter the dimension of the web (200) upon radial alteration of the conduit and thereby compensate for creep in the spiral conduit. In a particularly preferred embodiment the edge portion comprises a primary lock (214, 224) and a secondary or sacrificial lock (212, 222). The sacrificial lock is disengaged by release of the mechanism 215 to permit relative movement there between and thereby effect radial alteration of the conduit.
Patent NZ-627152-A (NZ)
Title: Safety helmet, in particular for mountain climbers and tree climbers
Inventor: GREBER MARTIN
IPC: A42B3/14
Filed: 2012-12-19
Abstract: What is described is a protective helmet comprising a helmet shell in which interior fittings are fixed which comprise an assembly contacting the head comprised of a supporting cage (42), a head band (44) und a neck strap. The interior fitting subassembly comprises three support arms (54, 55, 56) protruding laterally downwards from the supporting cage (42) in the temple areas or backwards and downwards in the area of the back of the head and formed as spacers as a means for a fixation on the helmet shell. In this way, the interior fitting subassembly is continuously held in a distance from the helmet shell along its entire outer circumference. A clearance which is therefore present around the interior fitting subassembly on all sides renders a relative dislocation of the helmet shell relative to the interior fitting subassembly possible. The free ends of the support arms (54, 55, 56) are releasably attached to the helmet shell, respectively. The releasable fixation of the support arm (56) protruding backwards and downwards comprises a latch lock effective in its longitudinal direction on a rear mounting point on the helmet shell, and, in addition, a suspension or support effective in its transverse direction in an additional mounting point positioned above the latch lock on the inside of the helmet shell. This results in an optimum introduction of force into the helmet shell and renders a relative dislocation of the helmet shell and therefore an optimum shock absorption by the helmet shell in combination with the interior fitting subassembly possible when a force both from above and from the side is applied to the helmet.
Patent NZ-705061-A (NZ)
Title: Methods and systems for energy balance control for feed flow and feed temperature disturbances
Inventor: CUMMINGS DANIEL LOUIS
IPC: G05B15/02
Filed: 2013-09-20
Abstract: The present disclosure provides methods and systems for mitigating finished product temperature transients caused by changes in product flow, raw product temperature, or other disturbances in an aseptic sterilization process. The methods and systems include applying an energy balance feedforward control scheme to the aseptic sterilization process to compensate for raw product temperature changes and changes in product flow. The methods and systems prevent damage to a finished product from occurring based on adverse transient temperature responses of heaters and coolers in an aseptic sterilization process.
Patent NZ-709564-A (NZ)
Title: Halogen-substituted pyrazol derivatives as pest-control agents
Inventor: FISCHER REINER
IPC: C07D403/04
Filed: 2014-02-03
Abstract: The invention relates to, inter alia, halogen-substituted compounds of the general formula (I) in which the groups A1-A4, T, n, W, Q, R1, and Z1-Z3 have the meanings specified in the description. The invention further relates to methods for producing the compounds of the formula (I) and to possible intermediates for producing said compounds. The compounds according to the invention are suitable in particular for combating insects, arachnids, and nematodes in the field of agriculture and for combating ectoparasites in the field of veterinary medicine.
Patent NZ-711445-A (NZ)
Title: Fusion immunomodulatory proteins and methods for making same
Inventor: GOVINDAPPA NAGARAJ
IPC: C12N15/62
Filed: 2014-03-10
Abstract: The present invention relates generally to the field of generating recombinant chimeric fusion proteins to be used in the cancer therapy, and more specifically, to fusion molecules of Anti- EGFRl-TGFβRII, Anti-EGFR1-PD1 and Anti-CTLA4-PD1 and methods of generating same, wherein the methods reduce production costs and increase homogeneity of the recombinant chimeric fusion proteins.
Patent NZ-713149-A (NZ)
Title: Enzyme preparations yielding a clean taste
Inventor: DE SWAAF MAXIMILIAAN PETER MARIE
IPC: A23L33/00
Filed: 2006-11-28
Abstract: Disclosed is a process to produce a lactase by a method comprising: (a) cultivating an arylsulfatase deficient host cell in a nutrient medium, under conditions conductive to expression of the lactase, wherein said arylsulfatase deficient host cell is a recombinant arylsulfatase deficient strain obtained by disturbing a gene coding for arylsulfatase activity, by inserting a marker gene into a gene coding for arylsulfatase activity, or by removal of part or all of the arylsulfatase coding region from the genome, (b) expressing the lactase in said host cell, and (c) recovering the lactase from the nutrient medium or from the host cell.