baber/WOPTO huggingface dataset:
Patent DO-P2018000153-A (DO)
Title: Derivados de 4-amino-2-(1h-pirazolo[3,4-b]piridina-3-il)-6-oxo-6,7-dihidro-5h-pirrolo[2,3-d] pirimidina y los respectivos derivados de (1h-indazol-3-il) como moduladores cgmp para el tratamiento de enfermedades cardiovasculares
Inventor: SUBHAREKHA RAGHAVAN
IPC: C07D487/04
Filed: 2018-06-22
Abstract: La invención proporciona compuestos de la Fórmula (I) (I) o una sal farmacéuticamente aceptable de los mismos, en la que X, Y, Z, R1, R2, R4, Ra y los subíndices m, p y q son tal como se describen en el presente documento. Los compuestos o sus sales farmacéuticamente aceptables pueden modular la producción corporal de guanosín monofosfato cíclico ("GMPc") y son generalmente adecuados para el tratamiento y la prevención de enfermedades que están asociadas con un equilibrio de GMPc perturbado. La invención también proporciona composiciones farmacéuticas que comprenden compuestos de Fórmula (I) o sales farmacéuticamente aceptables de los mismos. La invención también se refiere a procedimientos para el uso de los compuestos o sus sales farmacéuticamente aceptables en el tratamiento y la prevención de las enfermedades mencionadas anteriormente y para la preparación de productos farmacéuticos para este fin.
Patent DO-P2018000247-A (DO)
Title: Procedimiento para la preparación de cuerpos moldeados para la administración a animales
Inventor: PETER KLEINEBUDDE
IPC: A61K47/38
Filed: 2018-11-09
Abstract: La presente invención se refiere a un procedimiento para la preparación de cuerpos moldeados para la administración a animales, los cuerpos moldeados obtenidos de acuerdo con el procedimiento y el uso de los mismos.
Patent EC-SP10010104-A (EC)
Title: Sistema de administración vaginal
Inventor: HANES VLADIMIR
IPC: A61K9/00
Filed: 2010-04-14
Abstract: La presente invención se refiere a un sistema de administración intravaginal para la liberación controlada de drospirenona y un estrógeno y, opcionalmente, también comprende una o más sustancias terapéuticamente activas o promotoras de la salud capaces de brindar y/o mejorar la protección contra infecciones bacterianas y fúngicas, y/o mejorar la protección contra enfermedades de transmisión sexual. El sistema de administración comprende uno o más compartimientos, cada uno de los cuales comprende un núcleo y una membrana que recubre el núcleo, dicho núcleo y dicha membrana están compuestos esencialmente por la misma composición de polímero o una composición de polímero diferente, donde al menos un compartimiento comprende drospirenona y al menos un compartimiento, que puede ser igual o diferente del que comprende drospirenona, comprende un estrógeno o una mezcla de drospirenona y un estrógeno, y donde la membrana o la superficie de la membrana o al menos uno de los núcleos comprende dicha sustancia terapéuticamente activa o promotora de la salud.
Patent GB-189705502-A (GB)
Title: Improved Cord adjuster for Pictures and the like.
Inventor: SMITH ALFRED
Filed: 1897-03-02
Granted: 1898-01-08
Abstract: 5502. Smith, A. March 2. Pictures &c., hanging on walls.-A short rod C is formed with an elbow or extension, with an eye D and a plain eye E. The rod is threaded on the cord, as shown in Figs. 1, 3, or 4, and serves to adjust the picture. The rod C may be of wire, or be stamped or cast.
Patent GB-189707224-A (GB)
Title: Improved Stoppering Device for Vessels.
Inventor: HARTZ HERMANN CARL
Filed: 1897-03-19
Granted: 1897-04-24
Abstract: 7224. Hartz, H. C. March 19. Stoppers. - The stopper consists of two cork plugs a, b through which passes a screw c which works through a matrix i affixed to the lower plug. When the stopper is inserted and the screw rotated, the plugs are forced together longitudinally and expanded laterally, so as to form a tight joint with the neck of the vessel. The stopper is released by rotating the screw in the reverse direction. The upper end of the screw is provided with a ring c<2>, which is hinged at c<1> so that it can be turned down on the top of the stopper, and the lower end of the screw is enclosed by a casing h provided with a cap l.
Patent GB-189708025-A (GB)
Title: Improvements in Electrical connections for Tables and the like.
Inventor: BANKS OSCAR THOMAS
Filed: 1897-03-29
Granted: 1898-03-26
Abstract: 8025. Banks, O. T. March 29. Tables.-Relates to electric connections for tables, floors, walls, &c. Figs. 2 and 5 show one construction. The socket is formed with two compartments D, D containing smalt shot or the like and covered with a layer of insulating - material E protected by gauze F. The needles of the connecting - piece, Fig. 5, are thrust through the cover. Fuses J may be arranged on the cases. Single-pole connecting-pieces may be similarly constructed, the central partition being dispensed with.
Patent GB-189709419-A (GB)
Title: Improvements in Roller Bearings.
Inventor: WOODCOCK WILLIAM HUGH
Filed: 1897-04-13
Granted: 1898-02-19
Abstract: 9419. Woodcock, W. H. April 13. Roller bearings for rotating shafts or for wheels or pulleys revolving on fixed shafts. The rollers are held in position by a cage consisting of bars, alternate pairs of which are connected at opposite ends. The bars c have bearing surfaces for the rollers, and the connecting parts f have ribs g which bear o n suitable surfaces in the casing. The bearing surfaces c are prepared by means of an ordinary boring-tool.
Patent GB-189710388-A (GB)
Title: Improvements in Automatic Measures for Bottles and the like.
Inventor: JANES ALFRED EMERSON
Filed: 1897-04-26
Granted: 1898-03-12
Abstract: 10,388. Janes, A. E., and Rule, H. A. April 26. Measured quantities, delivering.-A bottle stopper x has an extended cylinder a in which moves by gravity a piston b with a long hollow rod d carrying a valve e. The cylinder is fitted with airvents h, g and a spout f. When the bottle is tilted for pouring out, the piston b falls and the cylinder fills until the former passes the spout and air-vent g. The valve e then cuts off supply, and the measured quantity is discharged. In a modified form, the valve is arranged to cut off the air supply to the bottle.
Patent GB-189713893-A (GB)
Title: Improved Spring Support for Railway Signal Lamps and the like.
Inventor: NOCON HANS
Filed: 1897-06-05
Granted: 1897-07-10
Abstract: 13,893. Nocon, H. June 5. Signal lamps.-The breakage of the glasses of railway signal &c. lamps, in consequence of the vibrations and shocks caused by passing trains and by the shifting of the points, is prevented by mounting the lamps F upon spring - supported plates D, instead of directly upon t h e plates B of the revolving axes A.
Patent GB-189721726-A (GB)
Title: Improvements in Machines for Cutting Paper and other Materials.
Inventor: BESSEY FREDERICK ADEE
Filed: 1897-09-22
Granted: 1898-01-08
Abstract: 21,726. Bessey, F. A. Sept. 22. Cutting-machines for paper &c.-In guillotine machines, the clamp c and knife D are connected by links p and q respectively with crank-pins on the eccentrically-mounted elliptical wheels n, o. The wheel o is mounted in fixed bearings, and the shaft i of the wheel n is carried by two pairs of links l, k from the shaft M of the wheel o and the shaft e respectively. The shaft e is also carried by a pair of swinging arms or links f from the driving-shaft b, which transmits motion to the elliptical wheels through the gearing c, d, g, h. The shaft e is made shorter than the distance between the end frames of the machine, while the ends of the shaft i pass through and move in slots i<1> in the end frames.
Patent GB-189725628-A (GB)
Title: Improvements in the Manufacture of Caps.
Inventor: LEMEL JULIUS
Filed: 1897-11-04
Granted: 1897-12-18
Abstract: 25,628. Lemel, J. Nov. 4. Caps ; ventilating.-Caps made in sections a are ventilated by uniting the sections together by strips b of braid or other material sewn to the sections along the lines d and having openings c along the centre.
Patent GB-189729503-A (GB)
Title: Improvements relating to Boiler Furnace Doors and the like.
Inventor: STOKOE ROBERT WILLIAM
Filed: 1897-12-13
Granted: 1898-01-15
Abstract: 29,503. Stokoe, R. W. Dec. 13. Doors for boiler &c. furnaces. On the face of the fire-door the latch A is pivoted at B. The longer arm of the latch is weighted, while the shorter arm enters one of a series of recesses in the boss E secured to the hinge bracket D. By these means the door may be secured in any desired position.
Patent GB-189803482-A (GB)
Title: Improvements in Spindles for Spinning and like Machines.
Inventor: BATTERSBY JAMES
Filed: 1898-02-11
Granted: 1898-07-02
Abstract: 3482. Battersby, J., and Fleisher, B. W. Feb. 11. S p i n d l e apparatus.-The spindle is provided with ball bearings. A sleeve A fixed in the rail has collars M, P screwed into it, in which are races or recesses to receive the balls, the other surfaces which bear upon the balls being formed respectively on an internallyprojecting portion J of the wharl F and on a collar T secured upon the lower end of the spindle. Each of the collars M and P is made in two parts, of which one is removable, and when in position serves to hold the balls in place. The lower end of the sleeve A is closed by a cap W, which serves as an oil reservoir.
Patent GB-189804182-A (GB)
Title: Improvements in Boots for Horses.
Inventor: FROST TOM
Filed: 1898-02-19
Granted: 1898-03-26
Abstract: 4182. Frost, T. Feb. 19. Horse-boots.-The ankle boot consists of a piece of unlined woollen material a, such as kersey, on the inside of which is stitched slightly unsymmetrically a piece b of the same material. Between the parts a, b is a padding of flock &c. e separated from the kersey by a waterproof material j. The piece a is prolonged at d, notched at e, bent outwards, and covered with leather g to form a flap to protect the fetlock.
Patent GB-189806764-A (GB)
Title: Improvements in Vaporizing Burners.
Inventor: FORSELLES ARTHUR AF
Filed: 1898-03-19
Granted: 1898-05-14
Abstract: 6764. Lake, H. H., [Forselles, A. af.]. March 19. Vapour burners.-Petroleum or other volatile oil, supplied under pressure to the lower end of the tube A, rises to its upper end, where it is vaporized and passes out by the fine opening C' of the tube C, thus drawing in air into the narrowed mouth B' of the mixing-tube B, over the gauze top D of which the mixture burns. The tube B may be widened at the bend as shown. In order to obtain a regular supply of oil and production of gas, a roll of wire cloth, or other material, or a series of diaphragms, is placed in'the tube A. The burner may be used for boiling, soldering, heating incandescent bodies, and like purposes.
Patent GB-189807510-A (GB)
Title: Improvements in or appertaining to Rolls of Ribbon.
Inventor: DAVIES JOHN
Filed: 1898-03-29
Granted: 1899-02-18
Abstract: 7510. Davies, J. March 29. Drawings to Specification. Measuring.-Relates to rolls of ribbon, and has for its object to indicate the length of ribbon on the roll. A strip of paper is rolled up with the ribbon, and is perforated with figures indicating the length in yards and quarters of yards.
Patent GB-189808287-A (GB)
Title: Combined Atmospheric Burner and Mantle and Chimney Lifter or Bearer.
Inventor: HERRIOT HENRY EDWARD
Filed: 1898-04-07
Granted: 1899-02-25
Abstract: 8287. H e r r i o t, H. E. April 7. Incandescent gas lamps.-Relates to improvements on the detachable gallery and mantle holder described in Specification No. 3554, A.D. 1898. The socket B or the lower end of the mantle rod A is connected by webs C to an elongated sleeve or tube D, which is attached to the gallery or chimney holder E. The gallery is not attached to the burner, but is supported thereon by the sleeve D, this construction permitting the parts E, D, A with the mantle in position to be readily removed from the burner and placed upon a table or other flat surface. The sleeve D may be either an addition to the burner or the outer tube of the burner itself. By slotting the gauze at the upper end of the burner, the webs C may be arranged on the same level with, or below, the gauze.
Patent GB-189810934-A (GB)
Title: Improvements in and relating to the Driving Mechanism of Chainless Velocipedes.
Inventor: POPE GEORGE
Filed: 1898-05-14
Granted: 1898-09-24
Abstract: 10,934. Pope, G. May 13. Ball bearings for cycles. Relates to driving-mechanism in which roller bearings are employed to take the side thrusts and ball bearings to take the end thrusts of the rotating shafts. Fig. 1 shows the application to a bicycle. A carrier E is located within the bottom bracket a<1>, and is adapted to carry the rollers F, G, which lie in contact with the crank-shaft sleeve B and the shell D. An adjustable cup H is fitted in one end of the casing I, and forms with the fixed cone K a race for the balls h. The gear end of the bracket a<1> is closed by a cap L to which is secured a felt retainer M, and between the two a dust washer m<2> is secured. The gear N is secured to the shaft r<1>, which runs within the fork R, by a tapered nut n, and is mounted upon rollers s<3> the bearing-sleeve S of which retains the parts s, s<2> in position. A thrust bearing is arranged at the rear end of the shaft.. This bearing consists of a ball case T mounted in the bracket extension O, between which and the cone t<1> balls are located. The bearing is adjusted by means of the nut t<2> operated through a slot in the casing O. The roller bearing aligner r<4> for the rear gear n<2> is separated from the ball bearing by a spacing washer r<3>. The axle U is secured at one end in the ear p<2> of the bracket cap p<1>, and is mounted upon rollers u<2> which are in contact with the roller bearings V, v<6> and are kept in place by retainers v<1>, v<2>, v<7> and the cone v<8>. The balls w for the end bearing take between the case w<1> and the cone v<8>, and the bearing is locked in the adjusted position by the frame connection R<1>. Washers w<2> and v<5> prevent the entrance of dust.
Patent GB-189813115-A (GB)
Title: Improvements in Ammunition Carriages.
Inventor: COCHRANE DOUGLAS MACKINNON BAI
Filed: 1898-06-11
Granted: 1899-04-29
Abstract: 13,115. Dundonald, D. M. B. H. Cochrane, Earl of. June 11. Ambulance vehicles; military transport carts.- The carriage is for military transport purposes, and may be employed for ammunition, ambulance, or as a gun carriage. The framing a is of steel tubes, and carries a number of bent tubes f constituting a pair of pyramidal frames for the horizontal tubes g on which a saddle is fitted. The shafts b are connected by arms h to the front pyramidal frame. The floor is formed of wire rope covered with raw hide or canvas.
Patent GB-189815519-A (GB)
Title: Improvements in, and in the Manufacture of, the Ribs and Stretchers of Umbrellas and Parasols, and in Appliances to be used therewith.
Inventor: HOLLAND WILLIAM
Filed: 1898-07-15
Granted: 1899-05-20
Abstract: 15,519. Holland, W. July 15. Rolling; drawing; working by electricity. -Relates to a method of making ribs and stretchers of umbrellas &c. of strong section. A hot wire is fed between two rolls b, c, on one of which is a rib c', and on the other a groove b<1>. The space between the rib and the groove is channel-shaped, but thickened at the base. In a modification, the wire is first rolled in a bar of lenticular section, and then rolled or drawn into the required channel section. The hardening and tempering is effected by electrically heating the rib &c., cooling in oil, and reheating to the necessary temperature for tempering.
Patent GB-189815562-A (GB)
Title: Improvements in Wooden Vessels and Barrels.
Inventor: KREPEL EVERHARDUS THEODORUS JA
Filed: 1898-07-15
Granted: 1899-05-27
Abstract: 15,562. Krepel, E. T. J. W. July 15. Hollow-ware, non-metallic; pails.-Pails and like vessels are formed of a single sheet or stave cut from a wooden trunk or block. By shaping the meeting-edges so to incline towards the top or bottom, a conical vessel will be formed ; and, by cutting with saw-cuts the top and bottom edges, a bilged vessel or cask will be formed. When the vessel is to be used for butter, it is fitted with a lining of oak &c.
Patent GB-189821841-A (GB)
Title: Improvements in the Armatures of Multipolar Dynamo Electric Machines.
Filed: 1898-10-17
Granted: 1898-12-17
Abstract: 21,841. Siemens Bros. & Co., Dumas, R., and Grimston, G. S. Oct. 17. Armatures.-The core-plates C are punched with dovetail notches into which fit the split arms A of the driving-spider. Wedge keys E expand the split arms tightly into the dovetail notches. The notches in the outer plates are strengthened by side strips F riveted at their edges. Bolts G hold the core-plates together. Dovetail tongues may project from the core-plates into dovetail spaces between the arms A, which are expanded as above.
Patent GB-189824293-A (GB)
Title: Improvements in Gas Governors.
Inventor: GOODSON JOHN
Filed: 1898-11-17
Granted: 1899-03-25
Abstract: 24,293. Goodson, J. Nov. 17. Regulators for supplying gas to burners and stoves. The supply socket b is provided with a gauze diaphragm l set below a floating diaphragm d, which carries a tube e. The tube e passes through a guide-diaphragm f, and opens into a chamber r from which the gas passes to the burner. A perforated cover g of the chamber r carries a nipple n, which acts with the tube e to reduce the supply of gas when the diaphragm rises. The parts may be variously arranged for burners of different kinds, and a regulating-screw may control one of the tubular paths for the gas.
Patent GB-189908377-A (GB)
Title: Improvements in Thill-couplings.
Inventor: STEVENS ACHILLES
Filed: 1899-04-21
Granted: 1900-02-24
Abstract: 8377. Stevens, A. April 21. Shafts, couplings for. Fig. 4 shows the shaft or thill disengaged. To couple, the padded slot 8 is pushed over the pin 4, and the thill 7 is turned until the end lugs 11 on the bar 10 rest in the curved slots 6 formed in ears of the plate 2, which is clipped to the axle.
Patent GB-189912041-A (GB)
Title: Collapsable Coop for Chickens and the like.
Inventor: TURNER EDWARD JOHN
Filed: 1899-06-09
Granted: 1900-05-05
Abstract: 12,041. Turner, E. J., and Turner, H. June 9. Poultry coops.-Relates to a coop having the top and four sides in separate pieces for convenience of storage. The barred front is formed with a top and bottom rail. The sides are fitted to the front by means of pins fitting into grooves C in the top rail, and are stepped at B to fit the bottom rail. The top fits at G under the top rail of the front, and is secured to the sides by eyes and pins at D. The back is secured to the sides by hooks and eyes.
Patent GB-189913565-A (GB)
Title: Improvements in Method of and Apparatus for Controlling Alternating Electric Current Motors.
Filed: 1899-06-30
Granted: 1900-01-27
Abstract: 13,565. British Thomson-Houston Co., [Armstrong, A. H.]. June 30. Switches.-Relates to the control of alternating- current motors by connecting them in series or parallel, or in A or Y connection. Fig. 1 is a diagram showing a developed controller L and a pair of motors. F<1> and F<2> represent the fixed parts, and A, A' the rotating parts. E', E<2> are the supply terminals, and G the ground connection. With the controller in the position K<1>, the motors are in series with the first motor in # connection. In the position K', the motors are in parallel and in Y connection. In the position K<3>, the resistance R is short-circuited. In order to prevent injurious sparking, a small supplementary shortcircuiting switch L', Fig. 4, is operated by the main controller L.
Patent GB-189916031-A (GB)
Title: A Cigar, Cigarette, or Pipe Holder.
Inventor: BURNETT ANDREW
Filed: 1899-08-05
Granted: 1899-11-18
Abstract: 16,031. Burnett, A. Aug. 5. Tobacco-pipes and cigar and cigarette holders.- Relates to a holder for cigarettes, cigars, or pipes, and consists of a handle portion AhavingaheadB, preferably in the form of a trident. The two outer prongs of the trident portion are formed with hooks or catches C on which the cigar, cigarette, or pipe stem is laid, and the central prong has an inverted clip C<1> which embraces the upper side of the cigar &c. The clip C' may be pivoted as at c, and pressed by a spring D. The lower end of the handle A may be provided with a fingerpiece or ring E.
Patent GB-189921720-A (GB)
Title: Improvements in and relating to Switches for Electric Light.
Inventor: BELL THOMAS
Filed: 1899-10-31
Granted: 1900-08-18
Abstract: 21,720. Bell, T., and Berry, S. S. Oct. 31. Switches; couplings.-Tumbler switch adapted for high voltages. The contact-lever c<1> is forked and is pivoted to the supporting-bracket e, and its ends work in recesses in the base a, which are separated by a bridge b to prevent sparking. The bracket e is fixed to a projecting part d of the base. The fixed contacts are connected to the terminals, which are fixed in the recessed base by nuts r. The porcelain handle k is recessed to receive a projection j on the cross-bar of the lever c<1>, and a spring n gives the quick break.
Patent GB-190000905-A (GB)
Title: Improvements in Annular Burners for Incandescent Oil Lamps.
Inventor: GRAETZ ADOLF
Filed: 1900-01-15
Granted: 1901-01-12
Abstract: 905. Graetz, A. Jan. 15. Incandescent oil lamps.-In argand burners, the conversion of the luminous flame into a non- luminous flame is effected by arranging the bentdown edge k<1> of the combined burner body and gallery k at a level about half-way between that of the top d<1> of the wick-tube and the flame-spreader b, and by the employment of a larger air tube f than usual in combination with the perforated cone q. When the wick is ignited and turned up, the part k<1> cause, the air supply to impinge upon the frame, converting the luminous flame indicated by the darker lines into the non-luminous flame indicated by the lighter lines in Figs. 4, 5, and 6. Additional air is supplied centrally to the upper part of the frame through the cone q. Access to the wick is facilitated by hinging the combined burner body and gallery k and c, and by attaching the outer wick-tube by means of the slotted end r.
Patent GB-190006138-A (GB)
Title: Improvements in and relating to Synchronous Motors, more especially applicable to Combined Cinematograhic and Phonographic Apparatus.
Inventor: SPOONER ARTHUR FREEMORE
Filed: 1900-04-02
Granted: 1900-12-22
Abstract: 6138. Spooner, A. F., [Joly, H.]. April 2. Magic-lanterns.-Relates to a method of synchronizing two electromotors, which may be used to drive simultaneously a phonograph and a kinematograph. Two escapement levers r, r are actuated by two electromagnets e, e, which are intermittently energized by electric currents sent by the two motors f, g at regular intervals determined by a definite number of revolutions, this being effected by a cam h geared to the motor shaft, and closing the circuit of a magnet e once in each revolution. The escapements on the ends of the levers r, r actuate the escapement wheels b, at a speed proportional to the speed of the respective motors to which they are connected. When the motors have. made the same number of revolutions, the spring l and the projection m are in contact, and the circuit of the driving-current of the motor g is closed. If the motor g should get ahead of the motor f, then the circuit of the motor g is broken and its speed is reduced until the motor f catches it up. Instead of breaking the circuit at l, m, a resistance may be introduced to reduce the current without stopping it. The regulator may act through a relay. One of the escapement wheels may be actuated mechanically from one of the motors.
Patent GB-190011543-A (GB)
Title: Improvements relating to Metallic Heart-plates for Domestic Fire-places.
Inventor: DENNIS WILLIAM LUKE
Filed: 1900-06-26
Granted: 1901-04-27
Abstract: 11,543. Dennis, W. L. June 26. Hearths, domestic, are formed of metal plates, cut to shape, and ornamented on one or both sides by enamelling or embossing. They may be fixed on pads of asbestos or other non-conducting material. The corners B are closely perforated, to enable portions to be easily cut away to fit the stove without damaging the enamel. The plate may be secured to a curb or fender, or may be formed with extensions, as shown, which can be bent along the dotted lines to form a combined hearth-plate and curb.