baber/WOPTO huggingface dataset:
Patent PH-12015000229-A1 (PH)
Title: Isolation and structure elucidation of novel ophiobolide b or 5-(1,3-dihydroxydecyl)-5-hydroxytetrahydrofuro[3,2-b]furan-2(5h)-one compound from ophiobolus sp. ktc 2293 fungus
Inventor: WILANFRANCO C TAYONE PH D
IPC: C07D405/00
Filed: 2015-06-26
Abstract: A novel compound was isolated from the culture broth of fungus Ophiobolus sp. KTC 2293. The structure of this molecule as shown in figure 1 was elucidated on the basis of Nuclear Magnetic Resonance (NMR) and Mass Spectroscopy (MS) analyses. The name of the compound bases on the International Union of Pure and Applied Chemistry (IUPAC) system is 5-(1,3-dihydroxydecyl)-5-hydroxytetrahydrofuro[3,2-b]furan-2(5H)-one. However, the aforementioned compound was given a chemical name Ophiobolide B.
Patent PH-12015501786-A1 (PH)
Title: Hybrid felts of electrospun nanofibers
Inventor: TODD MENKHAUS
IPC: H05B7/00
Filed: 2015-08-13
Abstract: The present invention relates generally to compositions for use in biological and chemical separations, as well as other applications. More specifically, the present invention relates to hybrid felts fabricated from electrospun nanofibers with high permeance and high capacity. Such hybrid felts utilize derivatized cellulose, and at least one non-cellulose-based polymer that may be removed from the felt by subjecting it to moderately elevated temperatures and/or solvents capable of dissolving the non-cellulose-based polymer to leave behind a porous nanofiber felt having more uniform pore sizes and other enhanced properties when compared to single component nanofiber felts.
Patent PH-12015502075-A1 (PH)
Title: Treatment of cataplexy
Inventor: KHAYRALLAH MOISE A
IPC: A61K31/03
Filed: 2015-09-11
Abstract: The present invention relates to a method of treating cataplexy in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds.
Patent PH-12016500538-A1 (PH)
Title: Inhibitors of kras g12c
Inventor: LIANSHENG LI
IPC: C07D215/46
Filed: 2016-03-21
Abstract: Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I): or a pharmaceutically acceptable salt, tautomer, prodrug or stereoisomer thereof, wherein R1, R2a, R3a, R3b, R4a, R4b, G1, G2, L1, L2, m1, m2, A, B, W, X, Y, Z and E are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods to modulate the activity of G12C mutant KRAS protein for treatment of disorders, such as cancer, are also provided.
Patent PH-12016500737-A1 (PH)
Title: Process for the preparation of a pde4 inhibitor
Inventor: ALESSANDRO FALCHI
IPC: A61P11/00
Filed: 2016-04-20
Abstract: The present invention relates to a process and intermediates for the preparation of compounds endowed with phosphodiesterase (PDE4) inhibitory activity having formula (I). The invention also relates to the process for the isolation by crystallization of the compound (I) and to its use for the preparation of pharmaceutical compositions for inhalation in combination with suitable carriers or vehicles. The present invention also relates to solvates and crystal forms of a compound of formula (I). The synthesized product is suitable for use in pharmaceutical applications for instance in the treatment of respiratory diseases.
Patent PH-12016501862-A1 (PH)
Title: Novel pyrazolo pyrimidine derivatives
Inventor: CAROLE PISSOT SOLDERMANN
IPC: A61P29/00
Filed: 2016-09-22
Abstract: The present invention describes new pyrazolo-pyrimidine derivatives of formula (I) or a pharmaceutically acceptable salt thereof; (I) wherein, R1 is halogen, cyano, or C1-C3alkyl optionally substituted by halogen; R2 is C1-C6alkyl optionally substituted one or more times by C1-C6alkyl, C2-C6alkenyl, hydroxyl, N,N-di-C1-C6alkyl amino, N-mono-C1-C6alkyl amino, O-Rg, Rg, phenyl, or by C1-C6alkoxy wherein said alkoxy again may optionally be substituted by C1-C6alkoxy, N,N-di-C1-C6alkyl amino, Rg or phenyl; C3-C6cycloalkyl optionally substituted by C1-C6alkyl, N,N-di-C1-C6alkyl amino or C1-C6alkoxy-C1-C6alkyl, and/or two of said optional substituents together with the atoms to which they are bound may form an annulated or spirocyclic 4 - 6 membered saturated heterocyclic ring comprising 1 - 2 O atoms; phenyl optionally substituted by C1-C6alkoxy; a 5 - 6 membered heteroaryl ring having 1 to 3 heteroatoms selected from N and O said ring being optionally substituted by C1-C6alkyl which may be optionally substituted by amino or hydroxy; Rg; or N,N-di-C1-C6alkyl amino carbonyl; and R is phenyl independently substituted two or more times by Ra, 2-pyridyl independently substituted one or more times by Rb, 3-pyridyl independently substituted one or more times by Rc, or 4-pyridyl independently substituted one or more times by Rd; which are generally interacting with MALT1 proteolytic and/or autoproteolytic activity, and in particular which may inhibit said activity. The present invention further describes the synthesis of said new pyrazolo-pyrimidine derivatives, their use as a medicament, especially by interacting with MALT1 proteolytic and/or autoproteolytic activity.
Patent PH-12017500389-A1 (PH)
Title: An advertising display
Inventor: LOPEZ FERNANDEZ FRANCISCO
IPC: A47F5/11
Filed: 2017-03-02
Abstract: Deployable display with an expansion system comprising a traction elastic element. The elastic element is basically formed by an elastic band which is annular or is cord-type with engaging elements, and optionally by at least one extension for extending the length of said band, formed by a plate made of flexible or semi-flexible sheet material provided with engaging elements for said elastic band, the assembly in turn being engaged to side projections of the display. The limiting system is implemented by the reduction in the elastic force and/or by the own resting length of the elastic band in cooperation, where appropriate, with the length of the extension element.
Patent PH-12017501295-A1 (PH)
Title: Bacillus thuringiensis subsp. kurstaki and bacillus thuringiensis subsp. aizawai combination formulations
Inventor: DEVISETTY BALA N
IPC: C12N1/20
Filed: 2017-07-14
Abstract: The present invention generally relates an agricultural formulation comprising a high potency Bacillus thuringiensis subsp. kurstaki strain and a Bacillus thuringiensis subsp. aizawai strain, wherein the weight ratio of Bacillus thuringiensis subsp. kurstaki to Bacillus thuringiensis subsp. aizawai is from about 20:80 to 80:20. The present invention is also directed to methods of manufacturing the formulation of the present invention and using the same to effectively control crop pests.
Patent PH-12017501382-A1 (PH)
Title: -2(het)aryl-substituted condensed bicyclic heterocycle derivatives as pest control agents
Inventor: FISCHER RUDIGER
IPC: C07D487/04
Filed: 2017-08-01
Abstract: The invention relates to novel compounds of formula (I), wherein R1, R2a, R2b, R3, A1, A2, A3, A4 and n have the meanings indicated in the description, to the use thereof as acaricides and/or insecticides for controlling animal pests, and to methods and intermediate products for the production thereof.
Patent PH-12017550028-A1 (PH)
Title: Solid forms of an ask1 inhibitor
Inventor: ANDRES MARK
IPC: A61P3/00
Filed: 2017-06-21
Abstract: Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.
Patent PH-12018500580-A1 (PH)
Title: Antibodies that specifically bind to tl1a
Inventor: POULTON LYNN DOROTHY
IPC: C07K16/28
Filed: 2018-03-16
Abstract: Recombinantly expressed variant antibodies that have enhanced affinity for TL1A and enhanced potency relative to the parent antibody from which they were derived are provided. The antibodies inhibit the interaction between TL1A and the death receptor 3 (DR3). The antibodies, or a composition thereof, may be used to treat one or more of asthma, COPD, pulmonary fibrosis, cystic fibrosis, inflammatory bowel disease, a gastrointestinal disease associated with cystic fibrosis, Crohn's disease, colitis, ulcerative colitis, irritable bowel syndrome, eosinophilic esophagitis, atopic dermatitis, eczema, scleroderma, arthritis, or rheumatoid arthritis.
Patent PH-12018501719-A1 (PH)
Title: Wire harness
Inventor: HAMASAKI RYOU
IPC: H02G15/04
Filed: 2018-08-14
Abstract: The present invention addresses the issue of providing a wire harness capable of responding to various needs of a user. This wire harness has a plurality of insulated electric wires sealed therein that have an insulation layer coated upon the surface of a conductor. The insulated electric wires are characterized by: having an exposed section not having the insulation layer coated thereupon and having the conductor exposed; at least the exposed section being sealed by an injection molded product; the plurality of insulated electric wires being present on an end section in the axial direction of the injection molded product, on the opposite side to the exposed section; the exposed section being present further on the other end side than a position (a 1/3 position) separated from the one end by a distance of 1/3 of the axial length of the injection molded product; and the outermost tangential line of the plurality of insulated electric wires in a first cross-section orthogonal to the axial direction, at the one end, being longer than the outermost tangential line of the plurality of insulated electric wires in a second cross-section orthogonal to the axial direction, at the 1/3 position.
Patent PH-12019500347-A1 (PH)
Title: Method for determining change in distance, location prompting method and apparatus and system thereof
Inventor: WANG NAN
IPC: G01S11/14
Filed: 2019-02-18
Abstract: A method for determining a change in distance, a location prompting method and an apparatus and a system thereof. The method for determining a change in distance comprises: a receiving terminal (112) acquiring acoustic signals at a preset frequency sent by a transmitting terminal (113) (step 11); according to the acquired acoustic signals, determining a change in distance between the transmitting terminal (113) and the receiving terminal (112) (step 12). The method for determining a change in distance provided herein can determine a change in distance between two terminals even when a relatively small positioned distance exists between the transmitting terminal (113) and the receiving terminal (112). The method also can generate corresponding prompt information according to the change in distance between two terminals, and the prompt information is used to prompt a user about a change in distance between the two terminals, and guide the users to move in a direction which decreases the distance between the two terminals; when a relatively small distance exists between two positioned users, the chance of the users finding each other is increased.
Patent PH-12019502915-A1 (PH)
Title: Immunogenic compositions
Inventor: AMBROSINO DONNA
IPC: C07K14/26
Filed: 2019-12-20
Abstract: Technologies for the prevention and/or treatment of nosocomial infections.
Patent PH-12020551054-A1 (PH)
Title: Absorbent article
Inventor: SAKAGUCHI SATORU
IPC: A61F13/532
Filed: 2020-07-09
Abstract: [Problem] To provide an absorbent article that is easy to pull up when wearing and can secure space for absorption of bodily fluids. [Solution] An absorbent article (10) includes an absorbent core (31) and side flaps (15) that extend outward of the absorbent core in the width direction. The total length, in the front-rear direction, of the absorbent core is divided into three so as to comprise a region, a crotch region, and a rear region. In the crotch region, the side flaps have a dimension of 30 mm or longer in the width direction. The crotch region (R13) has a center region (R13C) and side regions (R13S) that are positioned outside both sides of the center region in the width direction. Both outside edges of the center region have low basis-weight portions (33) provided along the front-rear direction. The center region has a front-rear contractive force that is higher than the front-rear contractive force of the side regions.
Patent PH-12020551977-A1 (PH)
Title: Formwork core for a formwork system for concreting a bell body
Inventor: REYMANN ANDREAS
IPC: E04G11/08
Filed: 2020-11-19
Abstract: The invention relates to a formwork core for a formwork system for concreting a bell body. On each base frame (60), two corner supports (54) are detachably fastened at a variable distance. The corner supports (54) each bear two corner connection panels (51), which are arranged at a right angle to each other around the corner and can be synchronously retracted and extended without touching each other. The corner supports (54) also bear corner angle pieces (55), which likewise can be retracted and extended and, in the completely extended state, close the gap between the two associated corner connection panels (51) in order to form a vertical outer shell of the formwork core (50). The vertical edges of the corner connection panels (51), which vertical edges are distant from the corner, have screw flanges (52a) facing inward. Optionally, at least one side formwork panel (52) can be inserted between the corner connection panels (51) of one side.
Patent PH-12021550011-A1 (PH)
Title: Methods and apparatus for monitoring vessel activity
Inventor: MCGRATH WILLIAM PATRICK
IPC: G06Q50/02
Filed: 2021-01-04
Abstract: Devices and methods are disclosed for monitoring at fishing vessels to detect blast fishing activity. A blast sensor is mountable to a vessel such that it produces a signal in response to pressure waves in water. A controller receives the signal and is operable to analyze the signal to detect blast events based on signal characteristics. A position measurement device measures a position of the vessel. A transmitter is provided to wirelessly transmit status information including a unique identifier of the monitoring unit and indicative of the position of the monitoring unit and to send a wireless alarm signal in response to a detected blast event.
Patent DE-102004006474-A1 (DE)
Inventor: CLEMENS WOLFGANG
IPC: F16B1/00
Filed: 2004-02-04
Abstract: The assembly of several separate components (23) is held together by connections (19) of shape memory alloy. A data carrier (17), e.g. an RFID tag, is incorporated in the assembly which stores instructions for the operation of a machine (11, 12) which takes the assembly apart. An independent claim is included for a method for taking the assemblies apart.
Patent DE-102004006649-A1 (DE)
Title: Verfahren zur Herstellung einer hochkonzentrierten Formaldehydlösung
Inventor: RUMPF BERND
IPC: C07C45/82
Filed: 2004-02-11
Abstract: Es wird ein Verfahren zur herstellung einer hochkonzentrierten Formaldehydlösung durch Abtrennung von Wasser aus einer niedriger konzentrierten Formaldehydlösung mit einem Formaldehydgehalt zwischen 5 und 50 Gew.-% vorgeschlagen, wonach man die niedriger konzentrierte Formaldehydlösung einem Vorwärmer zuführt und im Vorwärmer erhitzt, über eine Druckhaltevorrichtung entspannt und in einem Wendelrohrverdampfer unter Erhalt eines Brüdenstromes sowie der hochkonzentrierten Formaldehydlösung als Sumpfstrom aufkonzentriert, das dadurch gekennzeichnet ist, dass man die erhitzte niedriger konzentrierte Formaldehydlösung in der Druckhaltevorrichtung zu einem zweiphasigen Gemisch entspannt, das man dem Wendelrohrverdampfer zuführt.
Patent DE-102004010633-A1 (DE)
Title: Elektronisches Baulelement zum Verkleben einer Mehrzahl von Elektroden und Verfahren zum Montieren desselben
Inventor: SUDA YUSHI
IPC: H05K3/32
Filed: 2004-03-02
Abstract: Die vorliegende Erfindung zielt darauf ab, die Arbeitseffizienz zu verbessern, indem der Montagevorgang eines elektronischen Bautelements an einer Leiterplatte vereinfacht und eine Haftkraft des elektronischen Bauelements vergrößert wird, um eine mangelhafte Produktion zu verhindern. Bei der vorliegenden Erfindung weist eine Chipabdeckung mit Isoliereigenschaften und mit einem Wärmeabstrahlungsteil auf ihrer Unterseite einen Gehäuseteil auf. Ein Flip-Chipteil, das auf seiner Rückseite eine Elektrodenoberfläche aufweist, auf der eine Mehrzahl von überstehenden Elektroden eines Halbleiters angeordnet sind, ist im Gehäuseteil aufgenommen. Ein anisotroper Leitklebstoff ist auf die Elektrodenoberfläche des Chipteils aufgebracht oder aufgedruckt, um die überstehenden Elektroden einzubetten, und ein Isolierklebstoff ist in einer dickeren Ausbildung auf eine Klebe- oder Verbindungsoberfläche aufgebracht oder aufgedruckt, die auf einer Unterseite der Chipabdeckung und um das Chipteil herum vorgesehen ist, um die überstehenden Elektroden einzubetten. Der anisotrope Leitklebstoff und der Isolierklebstoff sind unter Wärmezufuhr mit Druck beaufschlagt worden, um sie vorübergehend zu erhärten.
Patent DE-102004012123-A1 (DE)
Title: 3/2 valve, for the pneumatic control of an assembly, has an equalizing opening at the closure body for the pressure to act on opposing part-surfaces to provide electromagnetic working with lower voltages
Inventor: RUNFT MICHAEL
IPC: F16K31/06
Filed: 2004-03-12
Abstract: The 3/2 valve, with a two-part housing (1), has a closure body (32) with at least one pressure equalizing opening (49). When the closure body is against a first valve seat (25) the pressure is equalized at the closure body so that the pressure at the inlet (6) acts on the part-surfaces (37,38) of the closure body towards and away from the valve seat. The two part-surfaces have identical dimensions. The closure body has a seal (40) towards the valve seat, and a membrane (44) on the side away from the valve seat towards the core (17) of an electromagnet (16).
Patent DE-102004012840-A1 (DE)
Title: Lufteinlassvorrichtung
Inventor: KINO HITOSHI
IPC: B01D46/52
Filed: 2004-03-16
Abstract: Eine Lufteinlassvorrichtung enthält eine Lufteinlassleitung, die mit einem Einlass versehen ist, durch den Einlassluft angesaugt werden soll, einen Luftreiniger, der auf der stromabwärtigen Seite der Lufteinlassleitung vorgesehen ist und zum Filtern der Ansaugluft dient, und einen Luftreinigerschlauch, der auf der stromabwärtigen Seite des Luftreinigers angebracht ist und zum Zuführen der gefilterten Ansaugluft an eine Brennkammer eines Motors dient, wobei der Einlassluftdurchlassweg zwischen dem Einlass und der Brennkammer gebildet ist. In einer Wand des Durchlasswegs, die eine Antinode eines niedrigeren Resonanzmodes, die der gesamten Durchlasswegslänge des Einlassluftdurchlasswegs entspricht, umgibt, sind ein Ventil zum Öffnen eines Verbindungswegs, der es dem Inneren des Einlassluftdurchlasswegs ermöglicht, mit der Umgebung des Einlassluftdurchlasswegs zumindest dann in Verbindung zu treten, wenn der niedrigere Resonanzmode auftritt, und ein luftdurchlässiges Element, das angebracht ist, um den Verbindungsweg zu blockieren, vorgesehen.
Patent DE-102004013332-A1 (DE)
Title: Lösbare Verbindungsanordnung für zwei rotationssymmetrische Bauteile
Inventor: MUELLER ANDREAS
IPC: F16B39/36
Filed: 2004-03-17
Abstract: Lösbare, kraft- und formschlüssige Verbindungsanordnung für zwei an einer Verbindungsstelle rotationssymmetrische Bauteile, insbesondere zur dichtenden Verbindung zwischen Verschlußteilen an Kraftwerksarmaturen, mit einem ersten Bauteil, das einen radial nach außen vorspringenden Bund mit einer ersten Spannfläche und einer ersten Anlagefläche aufweist, einer an einem offenen Ende eines zweiten Bauteils angeordneten Hülse für eine axial übergreifende Aufnahme des Bundes, einer in der Hülse zum Zusammenwirken mit der ersten Anlagefläche ausgebildeten zweiten Anlagefläche, einer entweder in der ersten oder in der zweiten Anlagefläche ausgebildeten Nut zur Aufnahme einer Dichtung, einer in der Hülse mit axialem Abstand zu der zweiten Anlagefläche ausgebildeten zweiten Spannfläche, und mit einer Anzahl von ringkeilförmigen Spannelementen, die über den Umfang verteilt und mit ersten Keilflächen gegen die erste Spannfläche und mit zweiten Keilflächen gegen die zweite Spannfläche anliegend angeordnet sind, dadurch gekennzeichnet, daß ein gegen dritte Keilflächen der Spannelemente mit einer äußeren Spreizfläche anliegender Spreizring und zwischen dem Spreizring und einem der Bauteile wirkende Spannmittel vorgesehen sind, mit denen der Spreizring axial und die Spannelemente radial oder radial-axial bewegbar sind.
Patent DE-102004018445-A1 (DE)
Title: Positionsanzeigesystem und dieses System verwendende Positionsanzeigevorrichtung
Inventor: KAWAGISHI TOSHIO
IPC: H04W64/00
Filed: 2004-04-08
Abstract: Ein Mobiltelefon (2) ist mit einer Bluetooth-Einheit zum Senden erfasster Positionsinformationen zu einer fahrzeuggebundenen Informationsausrüstung (1) über Kurzdistanz-Funkkommunikationen und einer Mobiltelefoneinheit zum Senden der erfassten Positionsinformationen zu der fahrzeuggebundenen Informationsausrüstung (1) über Mobilkommunikationen versehen, und die fahrzeuggebundene Informationsausrüstung ist mit einer Bluetooth-Einheit zum Empfangen der Positionsinformationen von dem Mobiltelefon über Kurzdistanz-Funkkommunikationen, einer Mobiltelefoneinheit zum Empfangen der Positionsinformationen von dem Mobiltelefon durch Mobilkommunikationen und einer Anzeigevorrichtung versehen.
Patent DE-102004018759-A1 (DE)
Title: Electrical lock, for doors and gates, has coils energized to act on the sliding bolt magnet and a jammed bolt can be allowed to move into position by a light shaking of the door/gate
Inventor: THEIS NORBERT
IPC: E05C1/08
Filed: 2004-04-16
Abstract: The electrical lock system, for doors and gates, has two electrically separate coils (3,4) behind each other within a stable housing (1) mounted in or on the door frame. A locking bolt (5) is within the interior, as a magnet (6) wholly or partially to be moved between locked and unlocked settings through selective activation of the coils. The coils are activated by time-defined current pulses, under electronic control. Should the bolt stick, shaking the door allows the bolt to move into the setting from the last command. The bolt is held in the open position by its magnet at a metal ring (2), and in the closed position by its own weight.
Patent DE-102004022957-A1 (DE)
Title: Operating method for in-line sheet-fed rotary printing press, involves operating press in first operating mode in which sheet support is held attached with sheet transport drum, and printing sheets are supported on sheet support
Inventor: BOGUHN HANS PETER
IPC: B41F21/00
Filed: 2004-05-10
Abstract: The method involves operating a rotary printing press (1) in a first operating mode in which a sheet support (7,8) is held attached with a sheet transport drum (6), and printing sheets are supported on the sheet support. The printing press is operated in a second printing mode in which the sheet support is detached from the sheet transport drum and stored in the printing press. An independent claim is also included for a printing sheets processing machine.
Patent DE-102004023774-A1 (DE)
Title: Windenergieanlage
Inventor: SCHUBERT MATTHIAS
IPC: F03D1/06
Filed: 2004-05-11
Abstract: Windenergieanlage mit einem Turm, einer auf dem oberen Ende des Turms angeordneten Gondel, einem Rotor, der um eine Rotordrehachse drehbar außen an der Gondel gelagert ist und der eine Rotornabe und mindestens ein sich von der Rotornabe erstreckendes Rotorblatt aufweist, wobei das Rotorblatt stumpfwinklig zur der Rotordrehachse vom Turm weg geneigt ausgerichtet an der Rotornabe angeordnet ist und dass das Rotorblatt in mindestens einem Längenabschnitt gekrümmt zu der Längsachse ausgebildet ist.