baber/WOPTO huggingface dataset:
Patent BR-112023000784-A2 (BR)
Title: Terapêuticos de ácido nucleico para transtornos genéticos
Inventor: CHRISTIAN MATRANGA
IPC: C07K14/155
Filed: 2021-07-16
Abstract: TERAPÊUTICOS DE ÁCIDO NUCLEICO PARA TRANSTORNOS GENÉTICOS. São fornecidas neste documento composições com base em retrovírus (por exemplo, lentivírus) compreendendo uma ou mais moléculas de ácido nucleico que codificam componentes da poliproteína Pol retroviral e uma molécula de ácido nucleico compreendendo um ou mais sequências transgênicas flanqueadas por sequências de repetição terminal longas, para liberação de um ou mais transgenes a uma célula alvo ex vivo ou in vivo. As composições são úteis para liberar a uma célula alvo (por exemplo, células-tronco hematopoieticas (HSCs), células hepáticas, células oculares, células musculares, células epiteliais, células T etc.) e/ou expressar de forma estável qualquer transgene (por exemplo, beta-globina, Fator VIII, regulador da GTPase RP (RPGR), distrofina, regulador da condutância transmembranar da fibrose cística (CFTR), um receptor de antígeno quimérico etc.) com um efeito biológico para tratar e/ou melhorar os sintomas associados com qualquer transtorno relacionado à expressão gênica (por exemplo, doença falciforme, beta-talassemia, hemofilia B, retinite pigmentosa, distrofia muscular de Duchenne, fibrose cística, câncer etc.).
Patent BR-112023015464-A2 (BR)
Title: Métodos e composições para prevenir ou reduzir neuroinflamação
Inventor: SWIFT ROBERT
IPC: A61K9/00
Filed: 2022-01-31
Abstract: métodos e composições para prevenir ou reduzir neuroinflamação. a divulgação fornece métodos e composições que compreendem cbd para prevenir, reduzir e/ou tratar neuroinflamação e sinais ou sintomas ou ambos de uma doença associada à neuroinflamação aguda ou crônica em um indivíduo em necessidade dos mesmos. uma composição é fornecida para prevenir ou reduzir a ativação celular da micróglia ou astrócitos ou ambos em um indivíduo em necessidade da mesma. métodos para prevenir ou reduzir sinais ou sintomas ou ambos associados à secreção excessiva de moléculas de sinalização inflamatória em um indivíduo em necessidade dos mesmos são fornecidos.
Patent BR-112023018619-A2 (BR)
Title: Inibidores de heteroaril de calicreína plasmática
Inventor: RAE ALASTAIR
IPC: C07D471/04
Filed: 2022-03-16
Abstract: inibidores de heteroaril de calicreína plasmática. a presente invenção fornece compostos e composições dos mesmos que são úteis como inibidores de calicreína plasmática e que exibem características desejáveis para os mesmos.
Patent BR-122013022103-A2 (BR)
Title: métodos e aparelho para mitigação de interferência de canal adjacente em estações base de ponto de acesso
Inventor: GAAL PETER
IPC: H04W52/24
Filed: 2010-03-12
Abstract: métodos e aparelho papa mitigação de interferência de canal adjacente em estações base de ponto de acesso. são descritas aparelho e métodos para mitigação de interferência em redes de comunicacão sem fio. em uma implementação, em um nó em uma primeira rede, um nível de potência e/o largura de banda ou canalizacão de um sinal de canal adjacente podem ser determinados, e um nível de potência e/ou largura de banda de um sinal transmitido na primeira rede pode ser ajustado em resposta a isso.
Patent CZ-999-A3 (CZ)
Title: Device for positioning rivets, buttons and the like
Inventor: HARDT MANFRED
IPC: A41H37/10
Filed: 1997-06-25
Abstract: A device for setting rivets, buttons or the like has an upper tool (21) and a lower tool (5). The upper tool (21) can preferably be actuated by a tappet and one of the tools carries out an evading movement during riveting. In order to provide a device of this type characterised by an improved manoeuvrability, a correct riveting and a highly reliable operation, without altering the proven basic design, the extent of the evading movement is used to monitor the riveting operation.
Patent CZ-27499-A3 (CZ)
Title: Circuit arrangement of railway vehicle traction drives with dynamic electric resistor braking, combined with dynamic electric regenerative braking and voltage amplifier
Inventor: FIRST ANTONIN ING
IPC: B60L7/22
Filed: 1999-01-27
Abstract: A series system consisting of an input inductance (3) a backup brake resistance (4) and a electronic switching element (5) is connected between a supply voltage first terminal (2) and a supply voltage second terminal (1), whereby a first diode (6) having poles arranged in forward direction for mains current is connected between the electronic switching element (5) and the backup brake resistance (4) and said diode (6) output is connected to a filter capacitor (7) the other pole of which is connected to the supply voltage second terminal (1), wherein said first diode (6) and said filter capacitor (7) common point is connected to a series system formed by a second diode (8) having poles arranged in reverse direction for the supply voltage or a switching element (12) with reverse characteristic and a recuperation resistance (9), whereby a switch (10) is connected between a common point of the input inductance (3) and the backup brake resistance (4) and a common point of the second diode (8) and the filter capacitor (7).
Patent CZ-52593-A3 (CZ)
Inventor: MOKRIS VACLAV ING
IPC: B21B1/28
Filed: 1993-03-29
Abstract: Zařízení na výrobu zpevňovačů do betonuvláknového tvaru
s tvarově uplavenými konci z pásu je řešeno tak, že před
jednotkou (4) příčného dělení pásu, opatřenou pevným
nožem (12) s břitem (14) a rotačním nožem (13) s břity (15),
je proti směru pohybu pásu (2) uspořádána jednotka (5) tvarování
okrajů pásu, obsahující alespoň dva horizontálnítvarovací
válečky (7) a dva vertikální tvarovací válečky (6),
Tvarovací válečky (6, 7) jsou uspořádané tak, žé roviny os
otáčení dvojice horizontálních tvarovacích válečků (7) a
dvojice vertikálních tvarovacích válečků (6)jsou souhlasné
nebo rovnoběžné. Břit (14) pevného nože (12) a břity (15)
rotačního nože (13) jednotky (4) příčného dělení pásu jsou
mimoběžné nebo rovnoběžné a nejméně jeden horizontální
tvarovací váleček (6) nebo vertikální tvarovací váleček (7)
jednotky (5) tvarování okrajů pásu je hnaný. Jednotky (5)
tvarování okrajů pásu spolu s jednotkami (4) příčného děleÍ
ní pásu mohou být uspořádány v lince, přesazené ve směru
pohybu vstupního pásu (3).
Patent CZ-65793-A3 (CZ)
Title: Aqueous coating materials
Inventor: DOOMEN WILLY FRANS ANNA
IPC: C08G18/62
Filed: 1993-04-16
Abstract: The present invention relates generally to aqueous coating compositions comprising a resin component including a functional group-containing crosslinkable resin and, optionally, a curing/crosslinking agent for functional groups of the crosslinkable resin. More specifically, the resin component includes, at least in part, a special anionically or anionically/non-ionically stabilized functional group-containing crosslinkable resin which can function as either the primary crosslinkable resin (self-emulsifying system) or as a reactive emulsifier for other lipophilic crosslinkable resins (stabilized system).
Patent CZ-81093-A3 (CZ)
Title: Catalytic system for stereospcific polymerization of alpha-olefins, polymerization process and the obtained polymers thereby
Inventor: COSTA JEAN-LOUIS DR
IPC: C08F4/655
Filed: 1993-05-04
Abstract: Catalyst system usable for the polymerization of  alpha -olefins, comprising:   - a solid based on complexed titanium chloride of  delta  crystalline form;   - an organoaluminium compound;   - an organic oxygen compound of silicon; characterized in that the organoaluminium compound is an unhalogenated compound.
Patent SK-24195-A3 (SK)
Title: Smoking system for delivering flavours and method for making same
Inventor: COLLINS ALFRED L
IPC: A24F40/46
Filed: 1993-09-10
Abstract: A removable cigarette (224') is manufactured for use in a smoking system which includes a lighter which has electrical heating means disposed in permanent cavity for delivering a flavored tobacco response to a smoker. To manufacture the cigarette a carrier web (259') is provided which has regions (261) of tobacco flavor material. Adhesive regions (261A) are applied from an adhesive applying station (327) to the surface of the carrier web (259') to form spaced regions of adhesive (261A) in between spaced regions of flavor material (261). A filter station (329) attaches filters (333,335) to the adhesive regions (261A) and a wrapping station (337) wraps the web (259') around the filters (333,335) to form a continuous rod of alternating regions of filter and tobacco flavor material. Finally, individual removable cigarettes (224') are formed by severing the continuous rod at a severing station (339).
Patent SK-48096-A3 (SK)
Title: Method and device for shearing elements of a nuclear plant
Inventor: SCHULTZ JEAN-CLAUDE
IPC: G21C19/36
Filed: 1994-10-18
Abstract: Method of shearing an element of a nuclear plant to be dismantled. The invention also concerns a device for carrying out said method, with the tool, for example a shear blade (7) having a cutting edge. The element to be sheared is held laterally, pushed towards the blade, and then removed by an arrangement comprising, for example, cylinders. The blade (7) is actuated, for example, by a dual action cylinder (6).
Patent SK-82019-A3 (SK)
Inventor: BRUTVAN MÁRIO
IPC: F16M11/26
Filed: 2019-01-11
Abstract: Základná konštrukcia stojana je tvorená štyrmi vertikálnymi tyčami (2) a jednou horizontálnou tyčou (1), pričom vertikálne tyče (2) sú s horizontálnou tyčou (1) spojené otočnými kĺbmi (4) alebo guľovými kĺbmi (15), ktorých polohy sú uzamknuté pákami (6) alebo skrutkami (5), a na horizontálnej tyči sú nasunuté obruče (3,24), na ktorých sú upnuté zveráky (7) držiakov.
Patent SK-84899-A3 (SK)
Title: Hair coloring compositions
Inventor: DIAS LOUIS CARLOS
IPC: A61K8/362
Filed: 1997-12-09
Abstract: A hair coloring composition comprising: (a) a preformed organic peroxyacid oxidising agent; and (b) an oxidative hair coloring agent; wherein the pH of each of components (a) and (b) is in the range of from about pH 1 to less than about pH 7 and wherein the pH of the composition is in the range of from about pH 1 to less than about pH 7. The products can provide excellent hair coloring and in-use efficacy benefits including excellent initial color and good wash fastness in combination with reduced hair damage at low pH.
Patent SK-88192-A3 (SK)
Inventor: VRABEC JAN
IPC: B60B37/00
Filed: 1992-03-24
Abstract: Vynález rieši zariadenie umožňujúce nápravám s koncovým
prevodom plynulú zmenu rozchodu kolies využitím
hnacieho momentu motora. Výstupný člen (1) koncového
prevodu otočné uložený v telese (2) nápravy je opatrený
vodiacou plochou (3), na ktorej je posuvne uložený hriadeľ
(4) kolesa. S hriadeľom (4) kolesa je spojený disk (6)
kolesa. Hriadeľ (4) kolesa je opatrený závitovou plochou
(7), protiplocha závitovej plochy je na telese otočné uloženom
v dutine axiálne neposuvného dna. Teleso (9) má
na voľnom konci posuvne uloženú objímku spojenú s
ovládacím piestom a s jednou časťou spojky. Druhá časť
spojky je spojená s vstupným členom koncového prevodu.
Pri rozpojenej spojke zapadajú výstupky spojené s výstupným
členom koncového prevodu do vybraní objímky
Patent SK-89498-A3 (SK)
Title: Method for producing cycloolefin
Inventor: ASHIDA KEITA
IPC: C07C7/20
Filed: 1998-06-26
Abstract: A process for producing a cycloolefin by partial hydrogenation of a monocyclic aromatic hydrocarbon with hydrogen in the presence of a ruthenium catalyst, water and a metal sulfate, wherein the hydrogenation is conducted while changing the concentration of the metal sulfate dissolved in an aqueous phase in which the catalyst is present.
Patent CH-647635G-A3 (CH)
IPC: G09G3/16
Filed: 1980-10-15
Abstract: An electrochromic display device has an electrolyte contained between two spaced-apart substrates. A set of display elements including first and second display elements are disposed on the surface of at least one of the substrates in contact with the electrolyte, and a counter electrode is disposed on the surface of the other substrate in contact with the electrolyte. Each of the display elements comprises a transparent electrode and an electrochromic layer disposed on the transparent electrode such that the display element exhibits either colored or bleached states depending on the amount of electric charge held by the display element. A charge transfer voltage is selectively applied between preselected bleached and colored display elements to effect transfer of electric charges through the electrolyte to thereby change the display state. Deterioration of the coloration exhibited by the colored display elements is compensated by applying a constant voltage between the first display element and the counter electrode, the value of the constant voltage being lower than that of the charge transfer voltage, and control circuitry controls the application of the constant voltage such that the constant voltage is applied before each predetermined number of transfers of electric charge held by the first display element to the second display element thereby maintaining the degree of coloration of the colored display elements.
Patent CS-108592-A3 (CS)
Title: Tufted carpet
Inventor: ERREN KARL-HEINZ
IPC: D04H11/00
Filed: 1992-04-09
Abstract: The invention relates to a tufted carpet which comprises a tufting material, a pile material and a carpet backing and essentially exclusively comprises nylon 6. The use of a chemically uniform material in all components of the tufted carpet allows the entire carpet to be recycled for recovery of the monomer starting material without separation into the individual components being necessary, which has hitherto prevented the recycling of tufted carpets and has resulted in considerable waste disposal problems.
Patent CZ-138093-A3 (CZ)
Title: DEXTROROTATORY ISOMER OF 6-(5-CHLORO-2-PYRIDYL)-5-(4-METHYL-1-PIPERAZINYL)CARBONYLOXY-7-OXO-6,7 -DIHYDRO-5 H-PYRROLO£3,4-b|PYRAZINE, PROCESS OF ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING SAID ISOMER
Inventor: COTREL CLAUDE
IPC: A61K31/497
Filed: 1992-01-16
Abstract: The dextrorotatory isomer of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1- piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine, its preparation and the pharmaceutical compositions containing it which can be used as tranquillisers and hypnotics.
Patent CZ-186292-A3 (CZ)
Title: Circuit arrangement of a processor for pseudorandom signal processing
Inventor: PANEK PETR ING CSC
IPC: H03K5/05
Filed: 1992-06-17
Abstract: The receiving signal is directed through the filter (1) with a rectangular envelope of impulse characteristics to the limiter (2) and then to the sampling registers (3,4) where it is sampled by clock impulses generated by the generator of clock impulses (13). The samples of the signal are directed to the EX-OR circuit (5,6) where it is multiplied by a reference pseudo-random code generated by the generator of pseudo-random codes (8). Then the samples are directed through the commutation circuit (7) to two addressable memory inputs (9). The memory is then addressed from the address input (93) of the phase shift setting. The values at the output of the memory (9) are alternatively summarised in summarising units (10,11) at the outputs of which there are samples of the quadrature parts of the output signal.<IMAGE>
Patent CZ-250991-A3 (CZ)
Inventor: VOLEJNIK JOSEF ING
IPC: E01B9/00
Filed: 1991-08-14
Abstract: Zařízení sestává ze dvou protilehle umístěných svěrek, skládající
se ze svisle orientovaného kotevního šroubu (3), na
který se navlékne svým oválným otvorem (9) klínovítě působící
stranová zarážka (8), opatřená na své vnější hraně vodící
drážkou (10), do které zapadá příchytka (11) svým dolů
sklopeným nosem vnější hrany. Příchyt ka (11) je na kotevní
šroub (3) navlečena svým kulatým otvorem a takto složená
svěrka je dota žená maticí (5) s podložkou. Vodorovná
podélná osa oválného otvoru (9) zarážky (8) je rovnoběž ná
s půdorysem podélné osy vodící drážky (10) a tyto osy svírají
s podélnou osou kolejnice (1) v půdoryse úhel ct= 20 až
30°. Vlastní dotyková plocha zarážky (8) a příchytky (11)
ve vodící drážce (10) je svou podélnou osou skloněna směrem
dolů od osy kolejnice (1) pod úhlem β= 1,0 až 1,5°.
Stranového posunu kolejnice (1) se dosáhne tlakem na čelo
zarážky (8) s potřebným uvolněním matic (5). Samosvorný
účinek je zajíš těn dotažením matic (5) kotevních šroubů (3)
obou protilehlých svěrek.
Patent CZ-347491-A3 (CZ)
Inventor: MACHAR ZDENEK ING
IPC: B28B7/10
Filed: 1991-11-15
Abstract: Zařízení pro výrobu žlabových dílců (1), opatřených spřa- hovacími třmeny (9) tvaru V, obsahuje ocelové skořepinové formy (2) s obvodovým rámem (6), nad jehož čelními příčlemi jsou uloženy stlačovací příčné nosníky (19) čelních odklopných stlačovacích rámů (20), uchycených kloubovými spoji k oběma čelním příčným rámovým příč- lím (10) základního mřížového rámu (8), obsahujícího podélné nosníky (11), na jejichž horních plochách jsou uloženy vytlačovací stoličky (12). Při odformování vytvrzených žlabových dílců (1) se pomocí stlačovacích hydraulických válců (16) stlačují příčné nosníky (19) a spolu s nimi obvodový rám (6) skořepinových forem (2) dolů, zatímco žlabové dílce (1) nemohou tento pohyb sledovat, protože jsou podepřeny svými spřahovacími třmeny (9) na vytlačova- cích stoličkách (12) a oddělí se tak od skořepinových forem
Patent CZ-382692-A3 (CZ)
Title: Chemical compounds
Inventor: BARTLETT ROBERT R
IPC: A61K31/277
Filed: 1992-12-22
Abstract: The Application relates to the products 
<IMAGE>
 in which: 
 
  - R1 represents 
<IMAGE>
 R13, R14 or R15 represent H, halogen or (C1-3)alkyl and n = 1, 2 or 3, 
  - R2 represents H or (C1-3)alkyl, 
  - R3, R4, R5, R6 and R7 represent H, halogen, NO2, CN, (C1-6 )alkyl, CO-(C2-6)alkyl, (C3-6)cycloalkyl, (C1-6)alkoxy or -alkylthio or -(CH2)m-CF3, -O-(CH2)m-CF3, -S-(CH2)m-CF3 , or a -CF2-Hal, -OCF2-Hal, 
<IMAGE>
 
<IMAGE>
 or 
<IMAGE>
 radical with R8, R9, R10, R11 and R12 having the values shown for R3, R 4, R5, R6 and R7, or form -O-CH2-O, 
 to their tautomeric forms and to their salts, as well as to a process for their preparation, to their application as medicaments, especially anti-inflammatories, and to the pharmaceutical compositions which contain them.
Patent CS-610585-A3 (CS)
Title: Mixture based on soluble alginates, bivalent metal salts and hydrocolloids
Inventor: CLARE KENNETH
IPC: A23L9/10
Filed: 1985-08-26
Abstract: Ions are controllably released into solution by novel blends of a hydrocolloid that is one or a combination of guar, oxidized guar, carboxymethyl guar, depolymerized guar, hydroxyalkyl guar, polyvinyl alcohol, carboxymethyl cellulose, xanthan gum, cold-water-soluble locust bean gum, cold-water-soluble starch, hydroxyethylated starch, and hydroxypropylated starch, and a calcium, barium, or strontium salt, in which the ratio of salt to hydrocolloid ranges from 10:1 to 1:20, based on total dry weights. They are rnixed with a soluble alginate in relative amounts such that the bivalent cation level is the amount theoretically necessary to convert 16-60% of the soluble alginate. The mixtures are especially useful in alginate print paste compositions and in preparation of various foods for humans and animals.
Patent CZ-125997-A3 (CZ)
Inventor: SVANCARA MILAN
IPC: F03G3/00
Filed: 1997-04-25
Abstract: Způsob je založen na využití gravitace použitím
tíhy břemen a energie padající hmoty k
uvádění do pohybu mechanizmu s cyklicky
obíhajícími břemeny /4/. Alespoň pět břemen
obíhá cyklicky v systému alespoň jedné dvojice
pásových mechanizmů /1, 2/, opatřených
nosiči /3/ pro břemena /4/, kde první pásový
mechanizmus /1 / dopravuje každé břemeno
/4/ dolů, kde je přemístěno na druhý pásový
mechanizmus /2/, který je dopravuje nahoru
a kde je přemístěno zpět na první pásový mechanizmus
/1 /. Zařízení k provádění způsobu
obsahuje alespoň jednu dvojici navzájem propojených
pohyblivých pásových mechanizmů
/1, 2/ s nekonečným pásem. Pásové mechanizmy
/1,2/ jsou opatřeny nosiči /3/, břemeny
/4/ a vodítky /5, 6/ a propojeny
prostřednictvím převodů / 7 / a celý tento systém
je opatřen zařízením pro využití vyrobené
mechanické energie.
Patent CZ-145594-A3 (CZ)
Title: Ligands carrying hetero atoms and their metal complexes
Inventor: KONDAREDDIAR RAMALINGAM
IPC: A61K51/04
Filed: 1994-06-13
Abstract: Novel compounds containing a heteroatom-bearing bridge and novel complexes of these compounds with metals. The novel compounds and complexes are useful as diagnostics and therapeutics.
Patent CZ-158394-A3 (CZ)
Title: Elastic bearing
Inventor: BITSCHKUS HORST
IPC: F16F1/377
Filed: 1994-06-28
Abstract: The invention relates to an elastic mounting (mount), intended, in particular, for supporting drive units in motor vehicles, with a supporting arm which projects laterally from the drive unit and is supported via elastomer bodies on a rigid abutment. To facilitate adjustment of the spring stiffness of the elastomer bodies and ensure a recycling capability, the invention provides for the supporting arm (1) to have an approximately cruciform cross-section with arms (4-7) which project obliquely sideways and for rubber bodies (10, 13-15) of elongate and prismatic cross-section cut from a continuous extrudate to be inserted for vertical and horizontal support between the arms (4-7) and the rubber bodies being surrounded by a housing (20) which is open towards the engine and is fastened to the abutment (25). <IMAGE>
Patent CZ-163694-A3 (CZ)
Inventor: SPALT ZDENEK JUDR
IPC: E04D1/26
Filed: 1994-07-07
Abstract: Laminovaný šindel je na svém kovovém provrchu a svých
bočních stěnách opatřen 10 až 50 g.m’2 akrylátového nánosu,
vytvrzeného svazkem urychlených elektronů-EB zářením.
Nános popřípadě obsahuje 2 až 10 % hmoty UV
absorbéru ze skupiny oxidů železa nebo mědi. Živičnou
vstvu šindele představuje asfaltovaný hydroizolační pás s
minerálním plnivem, kterým je živec a/nebo lupek, s výztužnou
tkaninou alespoň 200 g.m"2. Ve výhodném provedení
se k laminaci živičné vrstvy použije folie
elektrolytické mědi o tloušťce 12 až 40 .mi.m nebo válcované
mědi o tloušťce 20 až 50 .mi.m.
Patent CZ-168497-A3 (CZ)
Title: Sock with forward incline, particularly for snowboarding
Inventor: TURNER GEORGE F
IPC: A41B11/00
Filed: 1996-04-25
Abstract: A forward lean sock, that is particularly suited to snowboarding is provided. The snowboarding sock includes a woven sock body having a leg section and a foot section joined by a heel and front arch. The heel includes a Y-heel construction that provide an enhanced pouch of material at the heel to remove tension at the opposing front arch so that bunching is minimized in a forward lean position. The toe section can include reduced padding or a flat weave with no padding to provide more freedom of toe movement for the wearer.
Patent CZ-197394-A3 (CZ)
Title: Wedge joint
Inventor: MULLER SIEGFRIED
IPC: E04G5/06
Filed: 1993-12-17
Abstract: The invention relates to a wedge action connector, especially for construction equipment, with an extended support, a releasably securable holding component longitudinally movable thereon which is stable in position at various longitudinal points on the support, which has an aperture at least partially surrounding a support with a limited range of movement, the cross-section of which is somewhat larger in at least one direction transversely to the support than the latter's corresponding cross-section, and with a securing wedge having two impact ends, the cross-section of which increases in its longitudinal direction, which can also be inserted through a safety aperture merging into the acceptance aperture and which in the secured position, bearing laterally on the support, clamps the holding component securely in position against the support. To improve handling and reduce the space required, the invention proposes that the safety wedge is arc-shaped and both its impact ends point roughly in the same direction.
Patent CZ-201769-A3 (CZ)
Inventor: ŽVÁTORA PAVEL
IPC: C07D471/04
Filed: 2017-02-06
Abstract: Řešení se týká pevných forem 4-(4-{[4-Chlorfenyl)-4,4-dimethyl-1-cyklohexen-1--yl]methyl}-1-piperazinyl)--({3-nitro-4-[(tetrahydro-2-pyran-4-ylmethyl)amino]fenyl}sulfonyl)-2-(1-pyrrolo[2,3-]pyridin-5-yloxy)benzamidu vzorce Ι, známého jako venetoclax, způsobů jejich přípravy a použití pro přípravu farmaceutické kompozice.