baber/WOPTO huggingface dataset:
Patent BR-PI0509148-B1 (BR)
Inventor: BOEDECKER BERND
IPC: A61K38/54
Filed: 2005-03-21
Abstract: Orally administrable pharmaceutical compositions of lipase-containing products, particularly pancreatin and pancreatin-containing products, or of enzyme products which contain at least one lipase of non-animal, especially microbial origin, which improve the lipolytic activity and particularly result in stabilization of the lipase in the acidic pH range. These oral pharmaceutical compositions contain a system which includes at least one surfactant and one co-surfactant and optionally a lipophilic phase, and are self-emulsifiable on contact with a hydrophilic and a lipophilic phase. The compositions according to the invention are suitable for treating or inhibiting maldigestion, especially maldigestion due to chronic exocrine pancreatic insufficiency, in mammals and humans.
Patent BR-PI0510064-B1 (BR)
Title: suporte poroso e membrana para a filtração tangencial de um fluido a tratar .
Inventor: LESCOCHE PHILIPPE
IPC: B01D71/02
Filed: 2005-04-21
Abstract: suporte poroso e membrana para a filtração tangencial de um fluido a tratar e processo de fabricação de um suporte poroso. suporte poroso (1), para a filtração tangencial de um fluido a tratar, que apresenta pelo menos uma superficie (3) orientada para o fluido a tratar circulando segundo uma direção de circulação e uma superficie de saída (1~1~) para uma fração denominada permeado que atravessa o suporte poroso, este suporte sendo obtido por modificação de um suporte inicial, caracterizado pelo fato de que ele apresenta uma permeabilidade reduzida, em relação ao suporte inicial, e homogênea quando se desloca paralelamente à superficie (3) do suporte orientada para o fluido a tratar, segundo a direção de circulação do fluido a tratar
Patent BR-PI0511149-B1 (BR)
Title: Cutting tool, cutting insert and method for coating a cutting tool and a cutting insert
Inventor: DAVID J WILLS
IPC: C23C10/02
Filed: 2005-05-05
Abstract: ferramentas de cerâmica de al~ 3~o~ 3~ com camada realçada de ligação por difusão a presente invenção se refere a ferramentas de corte de cerâmica, tal como, um óxido de alumínio com ferramenta de corte de cerâmica de óxido de zircônio com camada realçada de ligação por difusão e revestimentos por cvd, particularmente úteis para usinagem de materiais de metal modernos. o método compreende uma reação química com uma mistura incluindo nitrogênio e cloreto de alumínio introduzido para formar uma camada realçada de ligação por difusão entre o substrato de cerâmica e os revestimentos por cvd. a ligação por difusão desse modo formada é altamente aderente ao óxido de alumínio com substrato de cerâmica de óxido de zircônio e significantemente realça as propriedades de revestimento por cvd, e desse modo melhora o desempenho da usinagem em termos da duração da ferramenta de óxido de alumínio com base em zircônio com as ferramentas de corte de cerâmica de óxido de zircônio.
Patent BR-PI0609029-B1 (BR)
Title: Dispositivo de dispensação farmacêutica
Inventor: DALJIT OHBI
IPC: C09K3/10
Filed: 2006-03-03
Abstract: vedação para uma valvula para uso em um dispositivo de dispensação farmacêutica, valvula para uso em um dispositivo de dispensação farmacêutica, dispositivo de dispensação farmacêutica, e, aparelho de dispensação para dispensar fluido pressurizado. uma vedação para uma válvula para uso em um dispositivo de dispensação farmacêutica, vedação esta sendo formada de um elastômero termoplástico incluindo um componente de propileno com cristalinidade isotática.
Patent BR-PI0823162-B1 (BR)
Title: processo destinado à produção de ácido forsfórico de alta pureza
Inventor: MOHAMED TAKHIM
IPC: C01B25/237
Filed: 2008-10-16
Abstract: processo destinado à produção de ácido fosfórico de alta pureza a invenção se refere a um processo destinado à produção de ácido fosfórico de alta pureza, que possui um teor muito pobre em antimônio, sendo adequado ao uso nas indústrias alimentícia, farmacêutica ou eletrônica.
Patent BR-PI0901656-B1 (BR)
Title: Instrumento cirúrgico configurado para uso com uma extremidade executora capaz de realizar um procedimento cirúrgico e método para processar um instrumento para cirurgia
Inventor: CHAD P BOUDREAUX
IPC: A61B17/068
Filed: 2009-02-16
Abstract: aparelho de grampeamento cirúrgico com mecanismo de queima sensível a carga. a presente invenção refere-se a um aparelho de grampeamento cirúrgico dotado de uma extremidade executora capaz de realizar um procedimento cirúrgico. o aparelho de grampeamento cirúrgico pode incluir uma lingueta de direcionamento que interfaceia com um cabo manualmente acionável. a lingueta de direcionamento pode ser dotada de um corpo de lingueta com um dente de direcionamento no mesmo que é configurado para interagir com um eixo de acionamento de modo que, na medida em que o cabomanualmente operável é acionado, o dente de direcionamento interage com o eixo de acionamento para fazer com que o eixo de acionamento aplique os movimentos de acionamento a um corpo alongado acoplado de modo operacional à extremidade executora. quando a extremidade executora experimenta uma carga de queima que excede uma magnitude predeterminada decarga de queima, o dente de direcionamento se move com relação ao corpo de lingueta para desengatar a partir do eixo de acionamento para evitartransferência adicional dos movimentos de acionamento ao corpo alongado embora o cabo manualmente operável continue a ser acionado.
Patent BR-PI0910465-B1 (BR)
Inventor: SIEBE CORNELIS DE VOS
IPC: C08L67/04
Filed: 2009-04-21
Abstract: The present invention pertains to a polymer composition comprising one of poly-D-lactide and poly-L-lactide bonded to an anionic clay mineral and the other of poly-D-lactide and poly-L-lactide not bonded to the anionic clay mineral. In a preferred embodiment, the anionic clay mineral is a hydrotalcite or a meixnerite. 
The polylactide composition according to the invention combines a high polymerisation rate with a low amount of contaminants in the system.
Patent BR-PI0914022-B1 (BR)
Title: Aplicador ergonômico para aplicação de uma composição cosmética aos cílios e respectivo método para aplicação
Inventor: DAVID CERUTTI
IPC: A45D40/26
Filed: 2009-10-09
Abstract: aplicador ergonômico para aplicação de uma composição cosmética aos cílios e respectivo método para aplicação trata-se de um aplicador ergonômico para aplicação de uma composição cosmética aos cílios. o aplicador compreende uma parte de cabo e uma parte de cabeça, sendo que o eixo geométrico longitudinal da parte de cabeça é posicionado ou pode ser rotativamente posicionado em um ângulo obtuso em relação ao eixo geométrico longitudinal do cabo. o cabo é adequadamente dimensionado para ser segurado entre o polegar e os dedos sem rotação do cabo. a parte de cabeça possui, em sua extremidade distai, meios para reter uma carga de composição cosmética e transferi-la aos cílios por contato com estes, tal como, mas sem a isto se restringir, cerdas, projeções, endentações, aletas, protuberâncias, velcro, dentes, ranhuras, esponjas e superfícies floculadas.
Patent BR-PI1007889-B1 (BR)
Title: Método para controlar a progressão de um veículo em um sistema de transporte por cabo
Inventor: ERIC BOGEY
IPC: B61B12/10
Filed: 2010-01-22
Abstract: método para controlar a progressão de um veículo em um sistema de transporte por cabo a presente invenção refere-se a um método para controlar a progressão de veículos (v1, vi) em um sistema de transporte por cabo (1), o referido sistema compreendendo: - veículos (v1, vi) com garras desacopláveis, os quais circulam a uma taxa d; - um cabo de tração (2) movido a uma velocidade operacional vc para conduzir os veículos (v1, vi) quando eles estiverem acoplados a ele; e - ao menos uma estação de embarque/desembarque de passageiros com uma seção em que os veículos (v1, vn), desconectados do cabo (2), são conduzidos por meios motrizes da estação. o método compreende: - uma etapa para determinar um valor-limite (sn, t), que varia em função da velocidade operacional vc do cabo (2) e/ou da taxa de circulação d dos veículos (v1, vi); - uma etapa de detecção que compreende transmitir um sinal de detecção quando da passagem dos veículos (v1, vi) em frente a ao menos um ponto de referência fixo (r1, rn+1); - uma etapa para medir uma variável (ln, i, kn, i+1), que representa uma extensão percorrida do cabo de tração (2) entre dois sinais de detecção; e - uma etapa para avaliar a progressão dos veículos (v1, vi) na estação comparando-se o valor-limite (sn, t) à variável (ln, i, kn, i+1), que representa uma extensão percorrida do cabo. a presente invenção também se refere a um dispositivo de controle e a um sistema de transporte por cabo.
Patent BR-PI1102849-B1 (BR)
Title: Processo e equipamento para limpeza a seco de cana-de-açúcar, colhida em toletes e contendo palha e outras impurezas
Inventor: Fernando César Boscariol
IPC: A01F12/30
Filed: 2011-06-20
Abstract: processo e equipamento para limpeza a seco de cana-de-açúcar, colhida em toletes e contendo palha e outras impurezas. o processo compreende as etapas de: distribuir uma carga de cana-de-açúcar, com impurezas minerais e vegetais, sobre uma esteira transportadora (12), aí formando um colchão de cana e impurezas; submeter o colchão a uma operação de dosagem e espalhamento, formando uma cortina fina e dispersa, em deslocamento gravitacional em uma primeira porção de câmara (15); submeter a cortina de cana e impurezas, a um fluxo de ar forçado, transversal e ascendente, deslocando as impurezas para fora da cortina e para o interior de um primeiro compartimento coletor (21) e de uma segunda e de uma terceira porção de câmara (22 e 27); defletir a fração de fluxo de ar forçado; recebida na terceira porção de câmara (27), obtusamente em uma pluralidade de persianas ajustáveis (28), descomprimindo o fluxo de ar; descarregar a carga de cana limpa e as impurezas através respectivas saídas inferiores de cana limpa (19) e de impurezas (21a, 23a e 26a).
Patent BR-PI1104082-B1 (BR)
Title: blindagem aparefeiçoada para cofres
Inventor: JOSEPH THOMAS ELBLING
IPC: E05G1/024
Filed: 2011-08-01
Abstract: BLINDAGEM APERFEIÇOADA PARA COFRES composta por uma parede externa (1) de alta resistência, um mosaico de placas cerâmicas (2) e uma placa de fechamento interna (3), também de aço de alta resistência.
Patent EA-000100-B1 (EA)
Title: Automatic weapon
Inventor: ABRAMYAN V V
IPC: F41G1/06
Filed: 1997-07-28
Abstract: An automatic weapon has a housing 1 with a movable spring-mounted barrel assembly 6 having a barrel 7 and a receiver 8. The receiver 8 has a spring-mounted bolt support 24 with a bolt 27, a buffer mechanism 32 and a firing pin mechanism 33 having a movable firing hammer 36 which interacts with the bolt support 24. The housing 1 has a trigger mechanism 50 with a firing trigger 52, a sear 43 with a spring-mounted pawl 18 interacting with the trigger 52 and the firing hammer 36, and a movable tripper 53 with cams (56, 67) interacting with the spring-mounted pawl 48 and the trigger 52. A device angularly displaces the barrel assembly 6 relative to the housing 1 and a muzzle attachment device 13 has expanding chambers with intercrossing cavities.
Patent EA-002801-B1 (EA)
Title: Method for preparation of citalopram
Inventor: ROCK MICHAEL HAROLD
IPC: C07D307/93
Filed: 1999-10-25
Abstract: 1. A method for the preparation of citalopram comprising reaction of a compound of Formula IV   wherein R is C1-6 alkyl, acyl, C1-6 alkylsulfonyl or arylsulfonyl, with 3-(N,N-dimethylamino)propyl magnesium halide, preferably 3-(N,N-dimethylamino)propyl magnesium chloride to afford citalopram   which is isolated as the base or a pharmaceutically acceptable salt thereof. 2. The method of Claim 1 characterised in that the intermediate of Formula IV is prepared by oxidation of the corresponding compound of Formula V:   wherein R is as defined in Claim 1. 3. The method characterised in that the compound of Formula V is prepared by protection of the hydroxymethylalcohol of (4-cyano-2-hydroxymethylphenyl)(4-fluorophenyl)methanol of Formula VI:   4. The method characterised in that the intermediate of Formula IV is prepared by oxidative cleavage of the corresponding compound of Formula VII:   wherein R is as defined in Claim 1. 5. The method of Claim 4 characterised in that the oxidative cleavage of the compound of Formula VII is effected by oxidation preferably performed by MnO<->4 (permanganates), ozone, RuCl3 or OsO4. 6. The method characterised in that the intermediate alkene of Formula VII is prepared by protection and dehydration of the corresponding compound of Formula III:   wherein the compound of Formula III is the R-enantiomer. 7. The method characterised in that the intermediate of Formula IV is prepared by the reaction of 5-cyanophthalide with 4-fluorophenylmagnesiumhalide, preferably 4-fluorophenylmagnesiumbromide followed by the reaction with R-X to prepare the ketone compound of Formula IV, wherein R is as defined in Claim 1 and X is a leaving group, preferably R-X is pivaloylchloride, 3,5-dimethoxybenzoylchloride, methyliodide, ethylbromide, tosylchloride, Me2SO4 or MeSO2Cl. 8. The method for the preparation of the racemic compound of Formula III comprising the steps of a) deprotecting a compound of Formula IV   wherein R is as defined in Claim 1 b) reacting the resulting compound of Formula VIII   with 3-(N,N-dimethylamino)propyl magnesium halide, preferably 3-(N,N-dimethylamino)propyl magnesium chloride to prepare the racemic compound of Formula III   9. The method of any of the Claims 1-8 wherein R is acyl, preferably pivaloyl, acetyl or optionally substituted benzoyl. 10. A compound of Formula IV:   wherein R is is C1-6 alkyl, acyl, C1-6 alkylsulfonyl or arylsulfonyl, preferably pivaloyl, acetyl or optionally substituted benzoyl. 11. Use of an intermediate of Claim 10 for the preparation of citalopram or S-citalopram.
Patent EA-009771-B1 (EA)
Title: Neublastin polypeptide, method for making thereof and use
Inventor: SAH DINAH W Y
IPC: A61P25/04
Filed: 2002-01-25
Abstract: The present invention relates to novel variant neublastin polypeptides that can be modified to enhance their pharmokinetic and bioavailability in vivo properties. The novel variant neublastin polypeptides conjugated with polymer moleculae. The invention also relates to nucleic acids encoding said polypeptides, to vectors comprising the nucleic acids, and to host cells comprising said vectors.The invention also relates to a method for making said polypeptides and hybrid proteins, and to use thereof for preparing a medicament for the treatment or prevention of nervous system disease or disorder.
Patent EA-004567-B1 (EA)
Title: Jet cutting device with deflector
Inventor: BLANGE JAN JETTE
IPC: E21B7/18
Filed: 2002-03-06
Abstract: 1. A jet cutting device for cutting a borehole, comprising a cutter head provided with at least one nozzle for ejecting a stream of fluid against a body so as to create a selected cut in said body, wherein, for each nozzle, the cutter head is provided with a deflector having a deflection surface arranged to deflect the stream of fluid ejected by the nozzle into a selected direction in accordance with the position of said cut to be created, characterized in that the deflection surface is arranged to deflect the stream of fluid close to and substantially parallel to the borehole wall. 2. The jet cutting device of claim 1, wherein said pump means is arranged to induce a stream of liquid including abrasive particles through the nozzle. 3. The jet cutting device of claim 1 or 2, wherein the deflection surface is concave. 4. The jet cutting device of any one of claims 1-3, wherein the impact force of the stream on the deflection surface varies along the deflection surface, and wherein the deflection surface has an erosion resistance which varies along the deflection surface in accordance with the variation of the impact force of the stream on the deflection surface so that the deflection surface is substantially uniformly eroded by the stream. 5. The jet cutting device of any one of claims 1-4, wherein the deflector is movable relative to the cutter head, and the jet cutting device further includes control means for controlling movement of the deflector relative to the cutting head. 6. The jet cutting device of claim 5, wherein the control means is arranged to move the deflector so as to displace a first portion of the deflection surface away from the location at which the stream impacts on the deflection surface, and to position a second portion of the deflection surface at said location. 7. The jet cutting device of claim 5, wherein the control means is arranged to move the deflector so as to change the angle at which said stream impacts on the deflector. 8. The jet cutting device of claim 5, wherein the control means is arranged to move the deflector in a translating movement so as to change the distance between the deflector and said stream. 9. The jet cutting device of any one of claims 1-8, wherein the cutter head forms part of a drill string for drilling a borehole into an earth formation, and wherein each nozzle is arranged to eject a stream of fluid including abrasive particles into the borehole so as to further drill the borehole. 10. The jet cutting device of claim 9, wherein each nozzle is arranged to drill a central part of the borehole by a portion of the stream ejected by the nozzle not deflected by the deflector, and to drill a radial outer part of the borehole by a portion of the stream deflected by the deflector positioned close to the borehole.
Patent EA-008108-B1 (EA)
Title: Combination of a nsaid and a pde-4 inhibitors
Inventor: HATZELMANN ARMIN
IPC: A61K/
Filed: 2002-09-17
Abstract: The invention relates to the combined administration of PDE4-inhibitors and NSAIDs for the treatment of an inflammatory disease and/or an inflammation associated disorder while minimizing gastrointestinal side effects, such as gastric erosions and ulcer, which are frequently associated with the use of NSAIDs.
Patent EA-006986-B1 (EA)
Title: Method and apparatus for transmitting signaling tones over a packet switched network
Inventor: SHOVAL ELI
IPC: H04M1/26
Filed: 2003-04-14
Abstract: As part of a system and method for transmitting a signaling tone over a packet switched data (or other communication) network, an audio encoder may have a speech encoding unit and a tone distorter. The tone distorter may distort one or more components of a signaling tone within an audio signal and the speech encoding unit may encode speech and the distorted signaling tone within the audio signal. A control signal may be sent to a tone generator to reproduce the distorted tone.
Patent EA-012834-B1 (EA)
Title: Novel carboxamide compounds having an mch-antagonistic effect, medicaments containing said compounds, and methods for the production thereof
Inventor: LEHMANN-LINTZ THORSTEN
IPC: C07D211/58
Filed: 2003-08-16
Abstract: The invention relates to carboxamide compounds of general formula (I),in which the groups and radicals A, B, W, X, Y, Z, U, U, R, R, R, R, [R], [R], n, m and k have the meanings indicated in claim 1. The invention also relates to methods for producing said carboxamide compounds and medicaments containing at least one inventive carboxamide. The inventive medicaments are suitable for treating metabolic disorders and/or eating disorders, especially obesity, bulimia, anorexia, hyperphagia, and diabetes due to the MCH receptor-antagonistic activity thereof.
Patent EA-010596-B1 (EA)
Title: Substituted pyrrolo-pyrazole derivatives as kinase inhibitors
Inventor: BRASCA MARIA GABRIELLA
IPC: A61P35/00
Filed: 2003-12-04
Abstract: Compounds represented by formula (Ia) or (Ib) and wherein R and R1 are as defined in the description, and pharmaceutically acceptable salts thereof, are disclosed; the said compounds are useful in the treatment of cell cycle proliferative disorders, e.g. cancer, associated with an altered cell cycle dependent kinase activity.
Patent EA-009079-B1 (EA)
Title: Liquid formulations of tumor necrosis factor-binding proteins
Inventor: SAMARITANI FABRIZIO
IPC: A61K47/02
Filed: 2004-02-11
Abstract: The invention relates to a stable, pharmaceutically acceptable, aqueous formulation of TNF-binding protein, comprising a TNF-binding protein, a buffer and an isotonicity agent.
Patent EA-009980-B1 (EA)
Title: Novel method for synthesizing esters of n-[(s)-1-carboxybutyl]-(s)-alanine and use thereof for synthesizing perindopril
Inventor: BREARD FABIENNE
IPC: C07D265/32
Filed: 2004-08-31
Abstract: The invention relates to a method for synthesizing derivatives of formula (I),in which R represents a linear or branched alkyl group (C-C). The invention is used for synthesizing perindopril and pharmaceutically acceptable salts thereof.
Patent EA-010304-B1 (EA)
Title: Process for producing dialkyl carbonate and diol
Inventor: TOJO MASAHIRO
IPC: C07C69/96
Filed: 2005-06-17
Abstract: A process for producing a dialkyl carbonate and a diol, comprising (a) subjecting a cyclic carbonate and an aliphatic monohydric alcohol to transesterification in the presence of a transesterification catalyst to produce a reaction solution containing a dialkyl carbonate and a diol, (b) extracting a dialkyl carbonate-containing reaction solution from the reaction solution and then separating a dialkyl carbonate from the dialkyl carbonate-containing reaction solution, and (c) extracting a diol-containing reaction solution from the reaction solution and then separating a diol from the diol-containing reaction solution. This process is characterized in that the content of a cyclic ether in the cyclic carbonate is 0.1 to 3,000 ppm and the content of carbonate ether in the dialkyl carbonate thus obtained is not more than 10,000 ppm.
Patent EA-010268-B1 (EA)
Title: A method of manufacturing the thermostructure panels and the equipment for its realization
Inventor: DICKENS LUTHER ISAAC
IPC: B29C70/68
Filed: 2007-05-21
Abstract: A method of manufacturing the thermostructure panels, comprising subsequent feed of granules of pre-foamed polystyrene and superheated steam into a split mold, purging, holding therein, cooling and removing the product, in which to the polysterene elements of a metal skeleton which preliminary covered with thermosetting adhesive, dispersion of rubbers and resins in solvents is used as the thermosetting adhesive.Thus the equipment for manufacturing the thermostructure panels, containing feed systems of granules of pre-foamed polystyrene and superheated steam into a split mold, the equipment is provided with a microprocessor for controlling systems, wherein the mold comprises magnetic and mechanical clamps for installation of elements metal reinforcing cage.