baber/WOPTO huggingface dataset:
Patent CA-3078800-A1 (CA)
Title: Anti-cd38 antibodies and methods of use
Inventor: WU LAN
IPC: C07K16/28
Filed: 2018-10-09
Abstract: The disclosure provides binding proteins that bind CD38 polypeptides, e.g., human and cynomolgus monkey CD38 polypeptides. For example, the binding proteins can be monospecific, bispecific, or trispecific binding proteins with at least one antigen binding domain that binds a CD38 polypeptide. The disclosure also provides methods for making binding proteins that bind CD38 polypeptides and uses of such binding proteins.
Patent CA-3079459-A1 (CA)
Inventor: TREMBLAY CONAN
IPC: A01K67/033
Filed: 2020-04-26
Abstract: The present invention comprise a novel insects water trough allowing high quantity huge (commercial/ industrial scale) of insect to drink easily and securely generally consisting of at least one close tube with one hole in the center, filled with water placed in the center of another half caped tube (can be more or less than an half tube) with screen going along each side of the half tube to allow the insects to climb in the half tube to drink the water dripping from the first close tube in the second half tube. The first closed tube have one hole in the center who when positioned downward or roll to de side can control the water level in the half tube bellow it
Patent CA-3079947-A1 (CA)
Title: Carbones modifies en reseau et leur fonctionnalisation chimique
Inventor: THOMAS ABHAY V
IPC: C01B32/186
Filed: 2018-10-23
Abstract: L'invention concerne un réseau de carbone fonctionnalisé chimiquement, formé selon un procédé consistant à chauffer un noyau de réseau de carbone dans un réacteur à une température comprise entre la température ambiante et 1 500°C. Le procédé peut également consister à soumettre le noyau de réseau de carbone à l'action d'un gaz carboné afin d'adsorber des atomes de carbone du gaz carboné sur les bords du noyau de réseau de carbone, à lier par covalence les atomes de carbone adsorbés les uns aux autres dans des cycles polyatomiques, une partie des cycles polyatomiques comprenant des cycles non hexagonaux, à lier par covalence les cycles polyatomiques les uns aux autres dans une ou plusieurs nouvelles régions de réseau s'étendant hors du noyau de réseau de carbone, ce qui permet de former un réseau modifié contenant les cycles non hexagonaux, et à soumettre une partie du réseau modifié à l'action d'un ou de plusieurs produits chimiques afin de lier un groupe fonctionnel et/ou une molécule au réseau modifié.
Patent CA-3081229-A1 (CA)
Inventor: BAGGIO OSVALDO
IPC: B65G43/02
Filed: 2018-10-30
Abstract: L'invention concerne un appareil, des systèmes et des procédés de surveillance de rouleau de transporteur. Selon certains modes de réalisation, un ou plusieurs capteurs (par exemple, des capteurs de température, des capteurs de charge, etc.) sont soutenus par l'arbre d'un rouleau de transporteur. Selon certains modes de réalisation, un ou plusieurs capteurs sont en communication de données avec un émetteur sans fil. Selon certains modes de réalisation, un générateur d'énergie entraîné par la rotation du rouleau est en communication électrique avec un ou plusieurs capteurs et/ou un émetteur sans fil. Selon certains modes de réalisation, une pluralité de systèmes de surveillance de rouleaux sont en communication de données avec un système de surveillance de transporteur et/ou un système de surveillance opérationnelle.
Patent CA-3082358-A1 (CA)
Title: System and method for carbon monoxide atmosphere stored blood components
Inventor: SHAKLAI NURITH
IPC: A01N1/00
Filed: 2018-11-16
Abstract: A system, apparatus, and method using carbon monoxide for treatment of platelets, and optionally other blood components and/or whole blood, allowing extended storage and increased viability of the stored blood platelets in vivo. The system allows an efficient use of the stored platelets by dividing the platelets into a population with a short residual lifetime for immediate use and a population that can remain in storage for longer. The storage apparatus enables safe platelet preservation and is equipped with an alarm to detect CO leakage.
Patent CA-3083009-A1 (CA)
Inventor: O'REILLY BROWN PATRICK
IPC: A23L5/00
Filed: 2012-07-12
Abstract: Provided herein are methods and compositions related to plant based meat substitutes which have properties similar to meat.
Patent CA-3084053-A1 (CA)
Inventor: VARKEY MATHEW
IPC: A61L27/18
Filed: 2018-12-07
Abstract: L'invention concerne des constructions cutanées et leurs procédés de fabrication et d'utilisation, par exemple pour le traitement des plaies et les essais de composés, notamment pour des essais de composés visant à tester l'efficacité, la toxicité, la pénétration, l'irritation et/ou le métabolisme de médicaments candidats ou de compositions candidates telles que des cosmétiques.
Patent CA-3085942-A1 (CA)
Title: Composes d'indole a substitution aryle et heteroaryle
Inventor: DYCKMAN ALARIC J
IPC: C07D451/02
Filed: 2018-12-19
Abstract: L'invention concerne des composés de formule (I) ou des sels de ceux-ci, dans laquelle A, G, R1, R5, et n sont définis dans la description. L'invention concerne également des procédés d'utilisation de tels composés en tant qu'inhibiteurs de signalisation par le récepteur 7 ou 8 ou 9 de type Toll et des compositions pharmaceutiques comprenant de tels composés. Ces composés sont utiles dans le traitement de maladies inflammatoires et auto-immunes.
Patent CA-3087628-A1 (CA)
Inventor: SANTI DANIEL V
IPC: A61K31/44
Filed: 2019-01-11
Abstract: Conjugates of topoisomerase I inhibitors linked to a macromolecule through a linkage that undergo beta elimination in situ in combination with one or more of an assessed defect in DNA damage response (DDR) in a subject bearing cancer, a cell cycle checkpoint inhibitor and/or a DDR inhibitor provides improved outcomes for cancer-bearing subjects.
Patent CA-3089453-A1 (CA)
Inventor: GOSSELIN MICHAEL A
IPC: A61K9/20
Filed: 2014-09-05
Abstract: The present invention is directed to orally administered compositions of topically acting corticosteroids for the treatment of inflammation of the gastrointestinal tracts such as eosinophilic esophagitis. The present invention also provides a method for treating conditions associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention as orally disintegrating tablets comprising a topically active corticosteroid adsorbed onto a pharmaceutically acceptable carrier such as silicified microcrystalline cellulose.
Patent CA-3096723-A1 (CA)
Inventor: LI MEI
IPC: C40B20/02
Filed: 2018-04-10
Abstract: A fluorescence image registration method, comprising: acquiring at least one fluorescence image of a biochip (S101); selecting a central local region of the center region of the fluorescence image (S102); acquiring pixel sum features of the central local region of the fluorescence image in a first direction and a second direction, the first direction being perpendicular to the second direction (S103); on the basis of template parameters selecting several first template lines and separately traversing the pixel sum features in the first and second directions to find the minimum values of the pixel sums corresponding to the several first template lines, the positions corresponding to the minimum values being track line positions (S104); in the local region of the track line positions, performing pixel-level correction on the track lines, the intersection point of the corrected track lines being the intersection point of pixel-level tracks (S105); on the basis of the pixel-level track intersection point, acquiring the positions of other track intersection points on the biochip and performing pixel-level correction on said other track intersection points (S106); on the basis of the center of gravity method, correcting the positions of the pixel-level track lines, to obtain the sub-pixel-level positions of the track lines (S107); by means of an even distribution gridding method, acquiring the sub-pixel-level positions of spots evenly distributed on the surface of the biochip (S108). Also provided is a gene sequencing system, a gene sequencing instrument, and a storage medium, able to optimize location and registration operations on fluorescent groups in fluorescence images.
Patent CA-3097143-A1 (CA)
Inventor: HOPPING GENE GREGORY
IPC: A61K47/64
Filed: 2019-04-19
Abstract: Compositions such as pharmaceutical compositions and uses for peptide-drug conjugates are disclosed. Such compositions can deliver a drug, a peptide, or a conjugate thereof to a target region, tissue, structure or cell in cartilage.
Patent CA-3097335-A1 (CA)
Inventor: MARTIN PARTHENA
IPC: A61K31/40
Filed: 2018-05-11
Abstract: 5-HT receptor agonists are useful in the treatment of a variety of diseases. Provided herein are methods of reducing the incidence and/or severity of seizures in a human patient using a 5-HT receptor agonist, such as, for example, a 5-HT4 agonist (e.g., fenfluramine). Methods of treating epilepsy or epileptic encephalopathy, and/or reducing, ameliorating or eliminating incidence of SUDEP in a subject diagnosed with epilepsy by administering a 5-HT4 agonist (e.g., fenfluramine) to a subject in need thereof are provided. Pharmaceutical compositions for use in practicing the subject methods are also provided.
Patent CA-3098882-A1 (CA)
Title: Fluid collection devices, systems, and methods
Inventor: SWEENEY LINDSAY ALISON
IPC: A61F5/453
Filed: 2019-04-29
Abstract: Example fluid collection devices and methods of assembling the fluid collection devices. The fluid collection devices include a fluid impermeable barrier and a fluid permeable body. The fluid impermeable barrier at least partially defines a chamber and includes an opening extending therethrough. The opening is configured to be positioned adjacent to or receive therein a urethra of a subject. The fluid permeable body has a singular porous material in a substantially cylindrical shape and positioned at least partially within the chamber.
Patent CA-3099233-A1 (CA)
Inventor: GABBAY JEFFREY S
IPC: D06M15/05
Filed: 2019-05-30
Abstract: There is provided an impregnated natural fiber including a cuticle and an interior lumen, the cuticle circumscribing the interior lumen; and insoluble particulates possessing a preselected property embedded in the fiber. The particulates comprise at least 0.1-30 wt.% of the impregnated fiber and the particulates are embedded on the cuticle and within the lumen of the fiber. The fiber has an increased strength, micronaire value and rate of water absorption. Also provided is a system for surface treating cellulose sliver fibers. The system includes a vessel containing a moist paste which comprises at least one particulate material possessing one or more preselected desired properties, a thickening agent and water. The paste from the vessel is dispensed directly onto sliver fiber ribbon(s). A bore sonotrode generates ultrasonic waves which embed the particulate material(s) in the sliver fibers.
Patent CA-3099739-A1 (CA)
Inventor: WIPF PETER
IPC: C07D233/61
Filed: 2019-05-13
Abstract: A compound, or a pharmaceutically acceptable salt or ester thereof, according to formula I: R20 (Z)b(Y)c(R21)a(X)dR22R23 wherein R20 is aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a thio-containing group, or a seleno-containing group; Z is alkanediyl, substituted alkanediyl, cycloalkanediyl, or substituted cycloalkanediyl; Y is S, O, S(=O), S(=O)(=O)-, or NR10, wherein R10 is H or alkyl; R21 is alkanediyl, substituted alkanediyl, cycloalkanediyl, substituted cycloalkanediyl, alkadienyl, substituted alkadienyl, cycloalkenediyl, substituted cycloalkenediyl, alkatrienyl, substituted alkatrienyl; X is -C(=O)-, -S(=O)(=O)-, orN(H)C(=O)-; R22 includes at least one divalent amino radical; R23 is aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a thio-containing group, or a seleno-containing group; a, b, c, and d independently are 0 or 1.
Patent CA-3100805-A1 (CA)
Title: Rotary tower with ballast
Inventor: IOTTI MARCO
IPC: B66F11/00
Filed: 2020-11-26
Abstract: ABSTRACT Described is ballast for a rotary tower, comprising: a main body (10), equipped with coupling means designed to allow a connection to the rotary tower; a detecting device (11, 12, 13), associated with the main body (10), designed for detecting the presence of an obstacle positioned at a distance less than a predetermined safety distance from the main body (10), and for emitting a proximity signal, signifying the presence of an obstacle at a distance less than the safety distance from the main body (10). [FIGURE 1] Date Recue/Date Received 2020-11-26
Patent CA-3100870-A1 (CA)
Inventor: KIM HEUNG BAE
IPC: A61B18/08
Filed: 2019-05-20
Abstract: An electrocautery device with a retractable suction tube is described. The electrocautery device includes a suction tube assembly that can move between an extended or retracted position using vacuum force generated by a suction source. In some embodiments, the suction tube assembly automatically locks into the extended position when extended such that axial force cannot cause the suction tube assembly to retract. The device may be suitable for use in laparoscopic procedures. The suction tube may be coaxially aligned with the electrocautery tip.
Patent CA-3102540-A1 (CA)
Title: Refractory core with enhanced acoustic properties
Inventor: ROSENBERGER TIMOTHY WAYNE EARL
IPC: F27D1/04
Filed: 2020-12-11
Abstract: ABSTRACT The disclosure is directed at a refractory core using insulators and noise dampening for use in an exhaust stack. The refractory core includes a framework that includes a plurality of spears that are used to hold insulation segments in place within the framework. The insulation segments includes noise-dampening slots. 17 Date Recue/Date Received 2020-12-11
Patent CA-3103252-A1 (CA)
Inventor: KAHOOK MALIK Y
IPC: A61F9/007
Filed: 2013-01-23
Abstract: Abstract A modular IOL system including intraocular primary and secondary components, which, when combined, form an intraocular optical correction device, wherein the secondary component is placed on the primary component within the perimeter of the capsulorhexis, thus avoiding the need to touch or otherwise manipulate the capsular bag. The secondary component may be manipulated, removed, and/or exchanged for a different secondary component for correction or modification of the optical result, on an intra-operative or post-operative basis, without the need to remove the primary component and without the need to manipulate the capsular bag. The primary component may have haptics extending therefrom for centration in the capsular bag, and the secondary component may exclude haptics, relying instead on attachment to the primary lens for stability. Such attachment may reside radially inside the perimeter of the capsulorhexis and radially outside the field of view to avoid interference with light transm ission. Date Recue/Date Received 2020-12-18
Patent CA-3109245-A1 (CA)
Title: Automated orthodontic treatment planning using deep learning
Inventor: ANSSARI MOIN DAVID
IPC: G16H50/70
Filed: 2019-09-03
Abstract: A method of the invention comprises obtaining training dental CTscans, identifying individual teeth and jaw bone in each of these CTscans, and training a deep neural network with training input data obtained from these CTscans and training target data.A further method of the invention comprises obtaining(203) a patient dental CTscan, identifying(205) individual teeth and jaw bone in this CTscan and using(207) the trained deep learning network to determine a desired final position from input data obtained from this CTscan. The (training) input data represents all teeth and the entire alveolar process and identifies the individual teeth and the jaw bone.The determined desired final positions are used to determine a sequence of desired intermediate positions per tooth and the intermediate and final positions and attachment types are used to create three-dimensional representations of teeth and/or aligners.
Patent CA-3110896-A1 (CA)
Inventor: HANSEN TIMOTHY ROY
IPC: G01N1/28
Filed: 2019-06-24
Abstract: An automated method for preparing a sample suspension. The sample suspension can be used for both MALDI and antimicrobial susceptibility (AST). A suspension is prepared, and a portion of that suspension is removed for a first analysis (e.g. MALDI), leaving a remaining volume. The turbidity of the remaining volume is measured. If the turbidity is below a first threshold, the suspension is not used for a second analysis (e.g. AST) and is subjected to a concentration protocol to raise the turbidity of the suspension. If the turbidity is within a predetermined range, a volume of the suspension is calculated that will deliver a predetermined amount of sample to a vessel for the second analysis. If the turbidity of the suspension is above the predetermined range, and the suspension has not been diluted a predetermined number of times, the suspension is diluted according to a dilution protocol.
Patent CA-3112401-A1 (CA)
Inventor: MORITZ ANDREAS
IPC: A61K39/00
Filed: 2019-09-13
Abstract: The present invention relates to a method for high throughput screening for a TCR- binding peptide ligand/MHC molecule complex, comprising a stabilized peptide-MHC molecule and respective uses of said method. The present invention further relates to polypeptides comprising or consisting of stabilized MHC molecules or peptide binding fragments thereof, pharmaceutical compositions comprising said polypeptides, vaccines comprising said pharmaceutical composition and uses of said vaccine for the manufacturing of a medicament and/or in the prevention of cancer The present invention further relates to nucleic acids encoding said polypeptides and vectors comprising said nucleic acids.
Patent CA-3115316-A1 (CA)
Title: A locking means for a transport cradle
Inventor: BREBNER PAUL JOHN GEORGE
IPC: B65D85/20
Filed: 2018-10-24
Abstract: A releasable lock (11) for a pipe cradle is disclosed. The releasable lock (11) comprises an elongate arm (1), pivotally secured at a first end to a pivot end mounted on a cradle frame (12). At a second end the releasable lock comprises a locking element (3), said locking element (3) being moveable between a release position allowing pivoting of the elongate arm (1) about the pivot end and a gripping position preventing said pivoting. The pivot end is moveable about a pivot pin (10) housed on the cradle, said movement displacing the elongate arm (1) between a first release position allowing removal or addition of pipes (15) from/to a cradle and a second position in which pipes are secured in position in the cradle.
Patent CA-3122237-A1 (CA)
Title: Method and apparatus for tracking one or more plants and/or plant based products and/or tracking the sale of products derived from the same, utilizing rfid technology
Inventor: DAGDELEN UYSAL DILEK
IPC: A01G7/00
Filed: 2015-06-12
Abstract: Abstract This invention is for tracking at least one plant. A method of this invention comprises: putting at least one seed or at least one stem in a corresponding at least one pot; positioning a corresponding at least one RFID tag with respect to the seed or stem in a manner, wherein the RFID tag comprises a strap; packaging a harvested material into a packaged product and attaching the RFID tag from the potted plant, or a product RFID tag that is associated with the plurality of tags to the packaged product; confirming a request for authorization by a RFID buy card; and after confirming ID information, transferring at least one product. Date Recue/Date Received 2021-06-14
Patent CA-3122835-A1 (CA)
Title: Flush-mount fan grille
Inventor: PETERSON JARED
IPC: F21S8/02
Filed: 2021-06-22
Abstract: A flush-mounted, in-ceiling exhaust fan grille for attachment to an exhaust fan housing includes a planar integration flange forming a perimeter of the grille. The integration flange includes a plurality of through holes along the perimeter.  An insert may be configured for insertion within the perimeter of the integration flange. A  light module may be configured to join within a central portion of the insert while maintaining an opening between an entirety of the light module and the insert. At least one spring may be attached to the insert on a first end and attached to the fan housing on a second end, wherein the at least one spring applies a force drawing the insert towards the fan housing.  An exhaust fan may be provided to draw air into the fan housing through the opening between the light module and the insert to be exhausted for proper ventilation.
Patent CA-3125092-A1 (CA)
Inventor: O'HALLORAN RAFAEL
IPC: G01R33/44
Filed: 2019-11-15
Abstract: L'invention concerne un appareil pour la commande d'au moins une bobine de gradient d'un système d'imagerie par résonance magnétique (IRM). Le système comprend au moins un processeur matériel; et au moins un support de stockage lisible par ordinateur mémorisant des instructions pouvant être exécutées par un processeur qui, lorsqu'elles sont exécutées par ledit processeur matériel, entraîne la réalisation d'un procédé par ledit processeur Le procédé peut comprendre la réception d'information spécifiant au moins une séquence d'impulsions cible; la détermination d'une séquence d'impulsions corrigée pour commander ladite au moins une bobine de gradient sur la base de ladite au moins une séquence d'impulsions cible et d'un modèle d'hystérésis de magnétisation induite dans le système IRM entraîné par le fonctionnement de ladite au moins une bobine de gradient; et la commande, au moyen de la séquence d'impulsions de gradient corrigée, de ladite au moins une bobine de gradient pour la génération d'une ou de plusieurs impulsions de gradient pour la formation de l'image d'un patient.
Patent CA-3127013-A1 (CA)
Inventor: RIEDEL JR
IPC: E21B43/26
Filed: 2021-08-06
Abstract: A fracturing system includes a plurality of junctions mounted on a chassis, such as a trailer chassis. Pressurized fluid is provided to the plurality of junctions via a plurality of conduits, e.g., from one or more pumps. The junctions and the conduits are independently mounted and independent vibration dampening systems damp vibrations at the individual mounts. Vibration of individual of the junctions may be damped by a first dampening system having first dampening properties and individual of the conduits may be damped by a second dampening system having second dampening properties different from the first dampening properties.
Patent CA-3133307-A1 (CA)
Inventor: RASOOLY JULIA A
IPC: A61M39/02
Filed: 2020-03-20
Abstract: Embodiments of a UV-transmissive needleless connector are provided. The connector comprises an outer housing that is at least partially UV-transmissive. The connector comprises a valve core configured to buckle to create a fluid path through the connector.
Patent CA-3133503-A1 (CA)
Inventor: CARSCALLEN WILLIAM MATHER ALMON
IPC: C12P17/06
Filed: 2019-04-29
Abstract: A genetically engineered microorganism for the production of a cannabinoid biosynthetic pathway product is described. The genetically engineered microorganism comprises at least one nucleic acid molecule encoding at least one cannabinoid biosynthetic pathway enzyme. The disclosure also relates to methods for producing a cannabinoid biosynthetic pathway product using a genetically engineered microorganism.
Patent CA-3133585-A1 (CA)
Title: Composition et procede pour produire des polymeres ayant subi une silylation et utilisation correspondante
Inventor: LANGERBEINS KLAUS
IPC: C08G18/28
Filed: 2020-03-20
Abstract: L'invention concerne une composition renfermant des polymères réticulant à l'humidité et un procédé pour produire ces polymères réticulant à l'humidité au moyen d'une catalyse faisant intervenir un composé métal-siloxane-silanol(ate), et l'utilisation de cette composition dans le domaine des produits CASE (revêtements, adhésifs, joints et élastomères), en particulier dans le domaine des matériaux adhésifs et des matériaux d'étanchéité.