Patent SG-11201407434X-A (SG)
Title: Amidophenoxypropanolamines
Inventor: GSTACH HUBERT
IPC: C07D295/088
Filed: 2013-06-10
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 19 December 2013 (19.12.2013) WIPOIPCT (10) International Publication Number WO 2013/186153 A3 (51) International Patent Classification: C07D 211/14 (2006.01) C07D 295/088 (2006.01) C07D 229/02 (2006.01) A61K31/166 (2006.01) C07C 235/46 (2006.01) A61K31/396 (2006.01) C07C 235/60 (2006.01) A61K31/445 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/EP2013/061880 10 June 2013 (10.06.2013) English English (30) Priority Data: 12171729.2 13 June 2012 (13.06.2012) EP (71) Applicant: MEDIZINISCHE UNIVERSITAT WIEN [AT/AT]; Spitalgasse 23, A-1090 Wien (AT). (72) Inventors: GSTACH, Hubert; Breite Gasse 17/5, A-1070 Wien (AT). CHIBA, Peter; Wilhelm Exnergasse 2/10, A- 1090 Wien (AT). MASTALIR, Matthias; Alserbach- strasse 10/12, A-1090 Wien (AT). (74) Agent: SCHWARZ, Albin; Schwarz & Partner, Wip- plingerstrasse 30, A-1010 Wien (AT). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (88) Date of publication of the international search report: 27 February 2014 (54) Title: AMIDOPHENOXYPROPANOLAMINES T-H 00 i-H o CJ (57) Abstract: The use of compounds of formula wherein R , 2 R , R , R , 3 4 5 R 6 and R have 7 several meanings, for the treatment of dis­ orders mediated by protozoan organisms, novel compounds of the above formula and intermediates for the preparation of such com­ pounds, pharmaceutical compositions comprising such novel compounds, method of treating disorders mediated a by protozoan or­ ganisms comprising administering such compounds, optionally together with second drug substance, a to a subject in need thereof and the use of such compounds, whenever comprising a photoaffinity label, for the identification of the molecular target(s) of arylamino alcohol antimalarials.