Patent SG-11201807191Y-A (SG)
Title: Apparatus for subretinal administration of therapeutic agent via a curved needle
Inventor: MEYER THOMAS E
IPC: A61F9/00
Filed: 2017-03-09
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 111111110111101110101011111010111110111011111011101011101011111111101111011111 International Bureau 0.. .... .. ...... ... (10) International Publication Number (43) International Publication Date WO 2017/156227 Al 14 September 2017 (14.09.2017) WIP0 I PCT (51) International Patent Classification: (74) Agents: SHIRTZ, Joseph, F. et al.; JOHNSON & JOHN- A61F 9/00 (2006.01) SON, One Johnson & Johnson Plaza, New Brunswick, New Jersey 08933 (US). (21) International Application Number: PCT/US2017/021508 (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (22) International Filing Date: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, 9 March 2017 (09.03.2017) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, (25) Filing Language: English DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (26) Publication Language: English KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, (30) Priority Data: MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, 62/305,767 9 March 2016 (09.03.2016) US NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, 15/438,918 22 February 2017 (22.02.2017) US RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (71) Applicant: JANSSEN BIOTECH, INC. [US/US]; ZA, ZM, ZW. 800/850 Ridgeview Drive, Horsham, Pennsylvania 19044 (US). (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (72) Inventors: MEYER, Thomas, E.; 214 Magnolia Street, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, Cincinnati, Ohio 45202 (US). KO, Benjamin, L.; 1425 TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, Main Street, Apt. 4F, Cincinnati, Ohio 45202 (US). TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, _ KHAN, Isaac, J.; 800/850 Ridgeview Drive, Horsham, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, — Pennsylvania 19044 (US). PRICE, Daniel, W.; 4545 LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, _ Creek Road, Cincinnati, Ohio 45242 (US). SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, OBERKIRCHER, Brendan, J.; 4545 Creek Road, Cin- GW, KM, ML, MR, NE, SN, TD, TG). = Ohio 45242 KEANE, Michael, F.; 800/850 cinnati, (US). Ridgeview Drive, Horsham, Pennsylvania 19044 Published: (US). — international 21(3)) with search report (Art. = = = = (54) Title: APPARATUS FOR SUBRETINAL ADMINISTRATION OF THERAPEUTIC AGENT VIA A CURVED NEEDLE = = 10----....\ = 26 30 = = II I 24 40 20 = - _ cNty SIP,1 44k 24 41 50 .''--- 11 .4 ,,.------ IN ei ei ,tD Fig.1 kin ,-1 IN (57) : An apparatus includes a body, a cannula (50), and a needle (100). The cannula is flexible and extends distally from 1-1 C the body. The needle is slidably disposed in the cannula. The needle includes a sharp distal tip (102) and a curved portion. The ei needle is configured to translate relative to the cannula between a proximal position and a distal position. The distal tip is configured O to be positioned inside the cannula when the needle is in the proximal position. The distal tip is configured to be positioned outside the cannula when the needle is in the distal position. The needle is resiliently biased to extend along a curve through the curved por - 5 tion.