baber/WOPTO huggingface dataset:
Patent NZ-562237-A (NZ)
Title: Proliferation signature and prognosis for gastrointestinal cancer
Inventor: ANJOMSHOAA AHMAD
IPC: C12Q1/68
Filed: 2007-10-05
Abstract: Provided is a method of predicting the likelihood of long-term survival of a gastrointestinal cancer patient without the recurrence of gastrointestinal cancer, comprising determining the expression level of one or more prognostic RNA transcripts or their expression products in a gastrointestinal sample obtained from the patient, normalized against the expression level of all RNA transcripts or their products in the gastrointestinal cancer tissue sample, or of a reference set of RNA transcripts or their expression products; wherein the prognostic RNA transcript or expression product comprises the transcript of replication factor (activator 1) 4 (RFC4); and establishing likelihood of long-term survival without gastrointestinal cancer recurrence wherein increased expression of the one or more prognostic RNA transcripts or their expression products indicates an increased likelihood of long-term survival without gastrointestinal cancer recurrence.
Patent NZ-563368-A (NZ)
Title: Exhalation valve for use in an underwater breathing device that creates an exhalation pressure to assist breathing
Inventor: JOHNSON MARK
IPC: B63C11/16
Filed: 2006-05-19
Abstract: An exhalation valve (100) for use in an underwater breathing device, such as a snorkel is disclosed. The valve (100) is configured to produce positive end-expiratory pressure in the airway of a user of the underwater breathing device in order to reduce the overall work of underwater breathing. The valve (100) includes a plate (120) defining an exhalation port (132) and also includes a flexible membrane (130) that is sealable against a surface of the plate and is sized and positioned to be capable of sealing the exhalation port (132). The flexible membrane (130) is configured to have a sealed position in which the flexible membrane (130) seals the exhalation port (132) such that substantially no exhaled air escapes the snorkel. The flexible membrane (130) is also configured to have an unsealed position in which exhaled air escapes the snorkel. The valve plate (120) is substantially rigid and substantially disc shaped.
Patent NZ-568694-A (NZ)
Title: Method, compositions, and kits for the treatment of medical conditions
Inventor: CHAPPELL TODD W
IPC: A61K31/33
Filed: 2006-11-08
Abstract: Disclosed is a use of prednisolone or prednisolone acetate and cyclosporine A in the manufacture of a medicament for the treatment of an ophthalmic disorder in a patient, wherein said prednisolone or prednisolone acetate is formulated at a concentration between 0.05% and 0.12% and said cyclosporine A is formulated at a concentration between 0.001% and 0.049% and wherein said composition is suitable for ophthalmic administration. Also described are methods, compositions, and kits for treating an immunoinflammatory disorder, an ophthalmic disorder, a musculoskeletal disorder or pain associated therewith, a periodontal disease, or a disease or condition associated with an increased serum CRP level.
Patent NZ-579602-A (NZ)
Title: Carton precursor having an intermediate ply made of multiple plastic tubes
Inventor: KWOK JOHN
IPC: B65D5/08
Filed: 2008-03-13
Abstract: A fold flat carton precursor for a liquid tight packaging carton. The precursor comprises a floor, a pair of side walls (4) and a pair of end walls (6) with diagonal fold flaps at the corners, each further comprising is made of a triple ply lamination, the top and bottom plies being plastic sheet, the intermediate ply being made of side by side thin walled plastic tubes. The intermediate ply is cruciform allowing the corners to be rectangular areas (14) of plastic plies joined together. These form diagonal fold flaps which are adhered to the cruciform blank to form the fold flat carton precursor. A lid is constructed in the same manner and overlies the carton to form a container which withstands tape wrapping.
Patent NZ-583652-A (NZ)
Title: Hepatitis c antiviral compositions and methods
Inventor: EWART GARY DINNEEN
IPC: A61K31/155
Filed: 2008-08-04
Abstract: Disclosed here are compositions comprising a substituted napthoyl guanidine derivatives of formula (I), wherein the substituents are as defined within the specification, and at least on additional agent having anti-viral activity selected from an interferon (IFN) and a nucleoside analogue inhibitor. Said composition is useful in the treatment of hepatitis C.
Patent NZ-589694-A (NZ)
Title: Annelated n-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
Inventor: KEIL STEFANIE
IPC: A61P25/00
Filed: 2009-05-22
Abstract: Disclosed is a annelated N-heterocycic sulphonamide with oxadiazolone head group of the formula I wherein y, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 are defined in the specification and X1,X2,X3,X4,X5 are independently N or CH; in all its stereoisomeric forms and mixtures in any ratio, and its physiologically acceptable salts and tautomeric forms. Also disclosed is a process to prepare said compound.
Patent NZ-592336-A (NZ)
Title: Adjustable headrest assembly for furniture member
Inventor: LAPOINTE LARRY P
IPC: A47C1/036
Filed: 2009-11-20
Abstract: Disclosed is a system for moving a furniture member (10) headrest (16) including an armrest (20) fixedly connected to a base (12). A back support (14) is connected to the armrest. A headrest is movably connected to the back support. A first adjustment member operates to rotate the headrest. The first adjustment member is positioned in a cavity between interior and exterior armrest frame elements and is manually movable. An actuation arm is rotated by a force received from the first adjustment member. An actuation link (42) is rotatably connected at a first end to the headrest portion and at a second end to the actuation arm (45), such that rotation of the actuation arm operates to displace the actuation link to rotate the headrest portion to a plurality of headrest support positions.
Patent NZ-593141-A (NZ)
Title: Cartridge for auto-injector apparatus including a frame extending beyond the needle tip, the needle tip and hub are proximally displaceable relative to the frame for insertion
Inventor: WILMOT JOHN G
IPC: A61M5/148
Filed: 2009-11-24
Abstract: A cartridge assembly for an auto-injector is disclosed comprising a flexible container (108) containing a liquid medicament (110), a needle hub (140) connected to the flexible container (108) and a needle (144) attached to and extending proximally from the needle hub (140). A frame (154) is connected to the needle hub (140) and includes a proximal end (156) that extends beyond the end (158) of the needle (144). The needle hub (140) and needle (144) are displaceable relative to the frame (158) in a proximal direction to insert the needle (144) into a patient.
Patent NZ-593962-A (NZ)
Title: Barley with reduced lipoxygenase activity and beverage prepared therefrom
Inventor: SKADHAUGE BIRGITTE
IPC: A23L7/20
Filed: 2009-12-28
Abstract: Disclosed is a beverage prepared from a barley plant, or a part thereof, wherein said beverage comprises less than 50% T2N potential compared to the T2N potential of a beverage prepared in the same manner from barley cv. Power. Said barley plant, or part thereof, comprises a lox-1 gene that encodes a mutated form of LOX-1, lacking some or all of amino acids 520-862 of LOX-1 resulting in a total loss of functional lipoxygenase (LOX)-1 enzyme, and said barley plant comprises a lox-2 gene that encodes a mutated form of LOX-2 lacking some or all of amino acids 515-717 of LOX-2 resulting in a total loss of functional LOX-2 enzyme.
Patent NZ-593974-A (NZ)
Title: Use of a liquid mineral composition for improving the adaptive response of plants to a change in environmental conditions
Inventor: DARIDON BRUNO
IPC: A01P3/00
Filed: 2010-01-12
Abstract: Disclosed is the use of a liquid mineral composition for leaf spraying comprising the following formula (I): Total ammoniacal nitrogen 0.08-2 percent Potassium 3-6 percent Magnesium 0.4-0.8 percent Sodium 1-2 percent Calcium 0-0.5 percent Total sulphates 3-6 percent Total phosphorous 0 percent Chlorides 1-2 percent Bicarbonates 1.2-3 percent Boron 0.1-0.2 percent Copper 0.018-0.03 Manganese 0.00005%-0.006 percent Iodine 0.02-0.04 percent Zinc 0.00005-0.006 percent Iron 0.0002-0.003 Water in a sufficient amount to bring the composition to 100 percent. The percentages consisting of percentages by weight compared to the total weight of the composition, for improving the adaptive response of plants to a change in environmental conditions.
Patent NZ-601829-A (NZ)
Title: Agent for preventing muscular atrophy
Inventor: NAITO HISASHI
IPC: A23C21/00
Filed: 2011-03-04
Abstract: Disclosed is a use of a whey protein hydrolysate having (1) a molecular weight distribution that is within a range of 10 kDa or less and has a main peak of 200 Da to 3 kDa, (2) an average peptide length (APL) of 2 to 8, (3) a free amino acid content of 20% or less, (4) a branched-chain amino acid content of 20% or more, and (5) an antigenicity equal to or less than 1/100,000th of that of β-lactoglobulin in the manufacture of a medicament for the prevention of muscular atrophy.
Patent NZ-607000-A (NZ)
Title: Glycodendrimers of polypropyletherimine
Inventor: SHAUNAK SUNIL
IPC: C08G73/02
Filed: 2011-08-22
Abstract: Provided is a glycodendrimer comprising: (a) a non-toxic dendrimer polypropyletherimine core supporting on average 9 to 64 terminal carboxylic acid groups, and (b) conjugated to said core 2 to 8 amino sugars or sulphate amino sugars, wherein each sugar is linked directly through a zero length amide bond with a residue of a terminal carboxylic acid group. The glycodendrimers may be used as anti-inflammatories or anti-infectives.
Patent NZ-611117-A (NZ)
Title: Anti mif antibodies
Inventor: KERSCHBAUMER RANDOLF
IPC: C12N15/13
Filed: 2008-12-30
Abstract: Disclosed is a monoclonal antibody or an antigen-binding portion thereof that specifically binds to the C-terminal or the centre region of macrophage inhibitory factor (MIF) and inhibits human MIF biological function, wherein said antibody or antigen-binding portion possesses at least one of the following properties: a) inhibits glucocorticoid overriding (GCO) activity b) inhibits proliferation of cancer cells or fibroblasts, and wherein the antibody is not an antibody selected from the group consisting of antibody Bax69 (SEQ ID NOs: 2 and 8), antibody Bax94 (SEQ ID NOs: 4 and 10), antibody Bax152 (SEQ ID NOs: 5 and 11) and antibody BaxA10 (SEQ ID NOs: 6 and 12), wherein SEQ ID NOs: 2-12 are disclosed within the specification. Also disclosed is the use of such antibodies in treating immunological diseases.
Patent NZ-611308-A (NZ)
Title: Designer endophytes
Inventor: SPANGENBERG GERMAN
IPC: C12Q1/68
Filed: 2013-05-30
Abstract: Disclosed is an endophyte variant having a desired genetic and metabolic profile, wherein said endophyte variant possesses genetic and/or metabolic characteristics that result in a beneficial phenotype in a plant harbouring, or otherwise associated with, the endophyte variant, when compared with a standard toxic control endophyte or with a non-endophyte control plant and wherein said endophyte variant is selected from the group consisting of NEA12dh5, NEA12dh6, NEA12dh13, NEA12dh14 and NEA12dh17.
Patent NZ-620470-A (NZ)
Title: Add-on window and insulation system
Inventor: PHILIP JOHN CARTER
IPC: E06B7/00
Filed: 2012-11-12
Abstract: A glazing frame profile configuration A that comprises two substantially parallel slots or recesses for locating a first and second glazing material respectively therein, with a first spacer 3 between the first and second layers of glazing material, and a second spacer 4 located against an exposed face of a pane of the glazing material such that the second spacer 4 is configured to be mounted against an existing window pane B. A gas or air filled cavity is created between the two layers of the first and second glazing material and a second gas or air filled cavity is created between the second glazing material and the existing window pane B. The glazing profile configuration A provides an edge cover to the two layers of glazing material, and includes a flexible material 12 mounted on an outside face of the second spacer 4, such that the flexible material 12 creates an airtight seal when pressed against the existing window pane B.
Patent NZ-627002-A (NZ)
Title: Non-sialylated anti-inflammatory polypeptides
Inventor: RAVETCH JEFFREY V
IPC: A61K39/395
Filed: 2012-12-10
Abstract: Disclosed is an isolated polypeptide comprising a modified sequence that is at least 75% identical to an IgG Fc region with the sequences of SEQ ID No: 1 or 2, and has a substitution at a position corresponding to F241 of SEQ ID No: 1 according to the Kabat numbering system, wherein the modified sequence is free of sialylation and the polypeptide has an anti-inflammatory activity that is higher than that of a parent polypeptide, wherein the sequences are as defined in the complete specification.
Patent NZ-706276-A (NZ)
Title: Windscreen installation apparatus and method
Inventor: DAVIES CHRISTOPHER
IPC: B62D65/06
Filed: 2011-11-02
Abstract: Apparatus for use in handling windscreens is disclosed. The apparatus may be used to install windscreens in a vehicle. The apparatus includes a windscreen anchor assembly (2) comprising a windscreen anchor device and a support arm (16) extending away from the windscreen anchor device. A mount assembly (3) is provided for supporting the windscreen anchor assembly (2). The mount assembly (3) includes a mount structure (11) for engaging with the support arm (16) such that the support arm can slide bodily in its longitudinal direction with respect to the mount structure (11). Additionally, the support arm is able to be dismantled into more than one piece for stowage, the anchor device and a dismantled arm part being provided with means for attaching to one another.
Patent NZ-707925-A (NZ)
Title: Pile driving point
Inventor: EGGERS ROBERT LESLIE
IPC: E04H17/22
Filed: 2012-11-28
Abstract: A pile driving point is disclosed. The point comprises a substantially conical nose (23) and a base (see 25, figure 8) for attaching the nose to the end of a pile (100). A plurality of arms (31), located radially about a body of the point, are deformable to extend in an axial direction for attachment to a pile. Each of the arms (31) has an aperture (33) for receiving a fastener for fastening the arm to the pile.
Patent NZ-716862-A (NZ)
Title: Methods and kits for the molecular subtyping of tumors
Inventor: WIRTZ RALPH
IPC: C12Q1/68
Filed: 2014-08-19
Abstract: A method of stratifying a breast cancer patient for adjuvant chemotherapy, (i) identifying a molecular subtype of a breast tumor in the breast cancer patient, and (ii) deciding in favor of or against adjuvant chemotherapy based on the molecular subtype, wherein the molecular subtype is identified by using an in vitro method comprising the steps: (a) determining the expression level of RNA transcript of human epidermal growth factor receptor 2 (HER2) in a sample of the tumor; (b) determining the expression level of RNA transcript of estrogen receptor (ESR1) in a sample of the tumor; (c) determining the expression level of RNA transcript of progesterone receptor (PGR) in a sample of the tumor; and (d) determining the expression level of RNA transcript of proliferation antigen Ki-67 (Ki67) in a sample of the tumor; and, optionally, (e) determining the expression level of RNA transcript of RacGTPase-activating protein 1 (RACGAP1) in a sample of the tumor, wherein the sample is RNA extracted from the tumor, wherein the expression level of RNA transcript is determined by reverse transcription (RT) quantitative PCR, and wherein no expression level of RNA transcript of a gene other than HER2, ESR1, PGR, Ki67 and, optionally, RACGAP1 and, optionally, one or more reference genes is determined, wherein the molecular subtype is selected from the group consisting of luminal A and luminal B, and wherein, if the molecular subtype is luminal B, it is decided in favor of adjuvant chemotherapy and, if the molecular subtype is luminal A, it is decided against adjuvant chemotherapy.
Patent NZ-724593-A (NZ)
Title: Anti-cd70 antibody drug conjugates
Inventor: HEWET AMHA
IPC: C07K16/30
Filed: 2013-06-19
Abstract: This invention relates to a compound comprising any one of Formula: (VIII), (IX), (XXXI), (XXXII), (XXXIII), (XXXIV), (XXXV), or (XXXVI) wherein the compound is an αCD70 antibody conjugated to a dolastatin, wherein the conjugation occurs via a non-naturally encoded amino acid in the antibody. Also disclosed herein is a method for derivatizing a dolastatin analog, wherein the derivatised dolastatin analog is an αCD70 antibody conjugated to a dolastatin, and wherein the conjugation occurs via a non-naturally encoded amino acid in the antibody. Further disclosed are methods for using such non-natural amino acid antibody drug conjugates, including therapeutic, diagnostic, and other biotechnology uses.
Patent NZ-727892-A (NZ)
Title: Slope and skew hanger
Inventor: WESNEY JOE L
IPC: E04B1/38
Filed: 2016-12-22
Abstract: A connector to attach a supported member to a supporting member, which is an inexpensive hanger for strengthening a connection between a ridge or valley member and a sloping and skewed rafter member or joist. A connection between a supported member and a supporting member, the connection comprising the supported member having a supported member with parallel sides, a top and bottom face, the supporting member having an attachment face in close proximity to or abuts an end face of the supported member, a connector having left and right generally planar back members that lie in a plane and are connected by a planar seat member that interfaces with the bottom face of the supported member; the connector further having left and right side planar support members attached to the left and right back members respectively and are non-parallel to the back member, the left and right side support members contact the attachment face of the supporting member and are not in contact with the left and right sides of the supported member, fasteners driven through the left and right sides of the support member into the supporting member
Patent NZ-731321-A (NZ)
Title: Methods of selecting t cell line and donor thereof for adoptive cellular therapy
Inventor: O’REILLY RICHARD
IPC: G01N33/50
Filed: 2015-11-04
Abstract: Disclosed herein are methods of selecting an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer. Also disclosed are methods of selecting a donor from whom to derive an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer. The methods relate to identifying and ranking of the indications of relative activities associated with a plurality of HLA alleles against a pathogen or against a cancer exhibited by the T cell lines restricted to the HLA alleles.
Patent NZ-733115-A (NZ)
Title: Processing biomass
Inventor: MEDOFF MARSHALL
IPC: B32B21/10
Filed: 2011-05-20
Abstract: Disclosed is a method of fermenting a saccharified cellulosic or lignocellulosic feedstock comprising, combining the saccharified cellulosic or lignocellulosic feedstock with saline water and fermenting the feedstock in the saline water to produce an intermediate or product, wherein the saline water is seawater or brackish water. The method can involve a microorganism such as yeast, fungus, algae, mould, bacteria or thermophilic microorganisms. The feedstock can comprise paper, paper products, wood, wood-related materials, grasses, rice hulls, bagasse, cotton, jute, hemp, flax, bamboo, sisal, abaca, straw, corn cobs, coconut hair, algae, seaweed, microbial materials and synthetic celluloses.
Patent NZ-735781-A (NZ)
Title: A process for producing hydrogen and graphitic carbon from hydrocarbons
Inventor: CORNEJO ANDREW
IPC: C21B15/00
Filed: 2016-03-31
Abstract: In accordance with the present invention, there is provided a process for producing hydrogen and graphitic carbon from a hydrocarbon gas comprising: contacting at a temperature between 600 °C and 1000 °C the catalyst with the hydrocarbon gas to catalytically convert at least a portion of the hydrocarbon gas to hydrogen and graphitic carbon, wherein the catalyst is a low grade iron oxide. Also provided is a method for the beneficiation of catalytic metal containing ore, the method comprising contacting at a temperature between 600 °C and 1000 °C the catalytic metal containing ore with a hydrocarbon gas to form a carbon-coated metal species.
Patent NZ-736868-A (NZ)
Title: Protective helmet
Inventor: AUERBACH PHILIPP
IPC: H04R1/46
Filed: 2016-05-10
Abstract: Helmets are often used in loud environments, where it is difficult to communicate with other persons due to the ambient noise. The present invention aims to solve this problem by improving the communication between the wearer of the helmet and other persons. The invention relates to a protective helmet (10) comprising a microphone (60) and an electronic device (80) for improving communication with the environment. In order to do so, the microphone is arranged on a supporting cage (50) below a shell (20) of the helmet and captures the sound waves that are generated by an organ of speech of the wearer of the helmet and propagate in the area of the supporting cage. The electronic device is located in a fitting space in a housing disposed on the outside of the helmet shell. A helmet shell attachment is connected to the helmet shell from the outside which forms part of the housing. The helmet shell attachment may open and close ventilation slots formed in the helmet shell by being shifted in a retainer provided on the helmet shell.
Patent NZ-737077-A (NZ)
Title: Peptide with anti-obesity and anti-diabetes activity and use thereof
Inventor: CHUNG YONG JI
IPC: C07K7/06
Filed: 2015-05-12
Abstract: A peptide and a peptide complex of the present invention, the peptide consisting of the amino acid sequence LKTRN and the peptide complex comprising peptides comprising the amino acid sequences LKTRN, KGASTGWMA, and either CDLRRLEMYC or SDLRRLEMYS. The peptide and peptide complex exhibit an anti-obesity effect by inhibiting fat accumulation and decomposing already accumulated fat, and exhibit an excellent effect with respect to diabetes by effectively reducing blood sugar. The peptide and the peptide complex of the present invention decrease the expression of PPARγ, ACC, and aP2, which are adipogenic markers, increase the expression of pHSL, AMPK-α1, CGI-58, and ATGL, which are lipolytic factors, and reduce the size of fat cells and blood cholesterol values. The peptide and the peptide complex of the present invention, which have excellent activity and safety, can be advantageously applied to drugs and quasi-drugs.
Patent NZ-743610-A (NZ)
Title: Scavenger compositions for sulfur species
Inventor: ONNEMBO GIOVANNI
IPC: C08K3/10
Filed: 2017-01-06
Abstract: The present invention is directed towards scavenger compositions for reducing hydrogen sulphide emissions for asphalt. In particular, the invention provides a scavenger composition for reducing hydrogen sulfide emissions from asphalt comprising: a carrier in an amount of 1.0 wt% to 99.0 wt.%, based on total weight of the composition, an active metal in an amount of 99.0 wt% to 1.0 wt.%, based on total weight of the composition, and a dispersant in an amount of 0.01 wt% to 10.0 wt.%, based on total weight of the composition, wherein the dispersant is chosen from sodium acid pyrophosphate, sodium polysulfonate, sodium alkyl sulfosuccinate, soy lecithin, hydroxyl-functional carboxylic acid esters, salts of unsaturated polyamine amides and lower molecular weight acidic polyesters, and alkyl amine sulfonates, wherein the active metal is a metal salt or metal chelate, and wherein the metal is chosen from iron, copper, molybdenum and zinc.