baber/WOPTO huggingface dataset:
Patent MX-2021009426-A (MX)
Title: Indazolyl-isoxazole derivatives for the treatment of diseases such as cancer.
Inventor: DORSCH DIETER
IPC: C07D487/04
Filed: 2020-02-10
Abstract: Compounds of the formula (I) in which R1, R2, X, Y and Z have the meanings indicated in Claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.
Patent MX-2021009655-A (MX)
Title: Inductor-based regenerative medicine compound.
Inventor: GONZALEZ LÓPEZ GERARDO MARTÍN
IPC: A61K38/20
Filed: 2021-08-11
Abstract: The present invention discloses a therapeutic medical application in chronic degenerative diseases, such as Diabetes Mellitus or Renal Insufficiency, exemplified in an enunciatively but non-limiting way by creating a compound of regenerative medicine based on inductors. Said compound includes factors, such as L-cysteine, interleukin 7 (IL-7), interleukin 3 (IL-3), monocyte colony-stimulating (M-CSF), granulocyte colony-stimulating (GMCSF0), mesodermal growth A1 (FGM), transforming growth factor-beta (TGFB), endodermal growth K2 (FGE), retinol, fibroblast growth (FGF), and neurological growth (FGF). Said elements work as inducers to release sufficient and safe amounts of stem cells in circulation, reactivating the functioning of the organ or area stimulated with said compound.
Patent MX-2021010417-A (MX)
Title: Coffee replicas produced from individual components.
Inventor: CHUA MARDONN CARL
IPC: A23F5/44
Filed: 2020-02-28
Abstract: Materials and methods for producing coffee replicas from individual components are provided herein.
Patent MX-2021011001-A (MX)
Title: Methods of preparing structural colorants.
Inventor: CZORNIJ ZENON PAUL
IPC: C09C1/24
Filed: 2020-03-11
Abstract: Disclosed in certain embodiments is a method of preparing structural colorants comprising photonic particles, the method comprising varying the calcination temperature in the process to enable the tuning of pore size to obtain a wide variety of possible colors.
Patent MX-2021012934-A (MX)
Title: Ionizable amine lipids and lipid nanoparticles.
Inventor: SCULLY STEPHEN S
IPC: C07C219/16
Filed: 2020-04-24
Abstract: The disclosure provides ionizable amine lipids and salts thereof (e.g., pharmaceutically acceptable salts thereof) useful for the delivery of biologically active agents, for example delivering biologically active agents to cells to prepare engineered cells. The ionizable amine lipids disclosed herein are useful as ionizable lipids in the formulation of lipid nanoparticle-based compositions.
Patent MX-2021014465-A (MX)
Title: Rnai constructs for inhibiting scap expression and methods of use thereof.
Inventor: MURRAY JUSTIN K
IPC: C12N15/113
Filed: 2020-06-01
Abstract: The present invention relates to RNAi constructs for reducing expression of the SCAP gene. Methods of using such RNAi constructs to treat or prevent liver disease, nonalcoholic fatty liver disease (NAFLD) are also described.
Patent MX-2021014803-A (MX)
Title: Anti-connective tissue growth factor antibody and application thereof.
Inventor: TAO WEIKANG
IPC: A61K39/395
Filed: 2020-06-03
Abstract: Provided are an anti-CTGF antibody comprising variable regions of a light chain and a heavy chain and a use thereof as a drug. The antibody may be used to prepare drugs for treating CTGF-related diseases or conditions.
Patent MX-2022000513-A (MX)
Title: Threaded connection for exploration and production of a hydrocarbon well.
Inventor: MUTIS RUEDA DAVID
IPC: E21B17/042
Filed: 2020-07-13
Abstract: A threaded connection for exploration and production of a hydrocarbon well and comprising a coupling member, a first tubular member and a second tubular member, wherein the coupling member has a coupling outer diameter, a first box part with first inner threads, and a second box part with second inner threads, the first tubular member has a first unthreaded tube part, and a first pin part with first outer threads, the second tubular member has a second unthreaded tube part, and a second pin part with second outer threads, the first inner threads and the first outer threads are configured to form a first inner primary seal at final make-up, and the second inner threads and the second outer threads are configured to form a second inner primary seal at final make-up.
Patent MX-2022003244-A (MX)
Title: Lc-ms methods for antibody isotyping and quantification.
Inventor: LI NING
IPC: G01N33/68
Filed: 2020-09-16
Abstract: The present invention provides methods and systems for isotyping and quantification of antibodies based on immunocapture and/or Liquid Chromatography-Mass Spectrometry (LC-MS) analysis. These antibodies are induced by the administration of pharmaceutical products. The immunocapture method comprises contacting samples with a solid support, wherein the pharmaceutical product has been cross-linked directly to the solid support. The MS analysis includes conducting peptide mapping, selecting unique peptides and fragment ions to generate MRM (multiple reaction monitoring) transitions, optimizing collision energy, and determining a LLOQ (lower limit of quantification).
Patent MX-2022009501-A (MX)
Title: Switching between stereo coding modes in a multichannel sound codec.
Inventor: EKSLER VACLAV
IPC: G10L19/008
Filed: 2021-02-01
Abstract: A method and device for encoding a stereo sound signal comprise stereo encoders using stereo modes operating in time domain (TD), in frequency domain (FD) or in modified discrete Fourier transform (MDCT) domain. A controller controls switching between the TD, FD and MDCT stereo modes. Upon switching from one stereo mode to the other, the switching controller may (a) recalculate at least one length of down-processed/mixed signal in a current frame of the stereo sound signal, (b) reconstruct a down-processed/mixed signal and also other signals related to the other stereo mode in the current frame, (c) adapt data structures and/or memories for coding the stereo sound signal in the current frame using the other stereo mode, and/or (d) alter a TD stereo channel down-mixing to maintain a correct phase of left and right channels of the stereo sound signal. Corresponding stereo sound signal decoding method and device are described.
Patent MX-2022009697-A (MX)
Title: Resource selection method and device, terminal, and medium.
Inventor: DING YI
IPC: H04W72/02
Filed: 2020-02-07
Abstract: The present application relates to the field of wireless communications. Disclosed are a resource selection method and device, a terminal, and a medium. The method comprises: determining a resource monitoring window, wherein the resource monitoring window comprises some of time slots before a time slot m where a selected resource is located; and when the monitoring result of the resource monitoring window is that a resource conflict occurs between the selected resource and a reserved resource of a second terminal, performing resource reselection for the selected resource. In the present application, the determined resource monitoring window only comprises some of the time slots before the time slot m where the selected resource is located, instead of all the time slots, and therefore, in a monitoring process of resource reselection, the time required for monitoring is reduced, and the power consumption of a first terminal is reduced.
Patent MX-2022011763-A (MX)
Title: Atomiser changing system for multi-axis hollow-wrist coating robots.
Inventor: HOLTMANN MATTHIAS
IPC: B05B15/65
Filed: 2021-03-25
Abstract: The invention relates to an atomiser changing system comprising a master unit (1) and at least one slave unit (2). The master unit (1) has at least the following components: a detachable connecting element (1.1) surrounding the centre of the master unit (1) for frictionally and interlockingly connecting (KS, FS) the master unit (1) to the slave unit (2); a coupling plate (1.2) located in the centre of the master unit (1) and having a plurality of coupling points for supplying substances, energy and/or information to an atomiser which can be connected thereto; and an adapter (1.3) for connecting the master unit (1) to a hollow wrist of a coating robot. The slave unit (2) has at least the following components: a coupling plate (2.2) for connecting the slave unit (2) to the master unit (1) and to an atomiser, wherein the coupling plate (2.2) is fixedly connected on the atomiser side to lines and/or an adapter plate for supplying substances, energy and/or information to the connectable atomiser; and a detachable connecting element (2.4) for connecting the slave unit (2) to an atomiser.
Patent MX-2022014389-A (MX)
Title: Diagnostic systems and methods of a continuously variable transmission.
Inventor: GILLINGHAM BRIAN R
IPC: B60W50/02
Filed: 2019-06-25
Abstract: A diagnostic system of a vehicle for diagnosing a drive belt of a continuously variable transmission. A diagnostic circuit detects or predicts a fault of the drive belt based on an operating parameter received from a sensor associated with the vehicle during a predetermined diagnostic period.
Patent MX-2022015506-A (MX)
Title: Pharmaceutical composition for preventing or treating periodontal disease or luxated teeth.
Inventor: PARK JOO HWANG
IPC: A61K38/08
Filed: 2021-06-01
Abstract: The present invention provides a pharmaceutical composition for preventing or treating periodontal disease or luxated teeth, comprising a peptide of a specific amino acid sequence, and a composition for periodontium regeneration.
Patent MX-PA01007063-A (MX)
Title: Conically jointed turbocharger rotor.
Inventor: JAMES W HEILENBACH
IPC: F01D5/02
Filed: 2001-07-11
Abstract: A turbocharger rotor includes a turbine wheel, a compressor wheel, a shaft extending between the turbine and the compressor wheels for rotation together about an axis, and connecting means including two pairs of non-locking cones. In a preferred embodiment, the cones include external cones on the turbine and compressor wheels and internal cones on the ends of the shaft. The non-locking cones are centered on the axis with the external and internal cones drivingly engaging one another to align and connect the wheels with the shaft. A long bolt fastener extends through the compressor wheel and the shaft to engage the turbine wheel and hold the rotor components in assembly. An alternative embodiment includes engaging radial surfaces outward of the cones. The radial surfaces share the transmission of torque through the connecting means and assist in stabilizing the joints between the shaft and the connected wheels.
Patent MX-PA01008445-A (MX)
Title: Gas-solid separation process.
Inventor: DRIES HUBERTUS WILHELMUS ALBER
IPC: C10G11/18
Filed: 2000-02-22
Abstract: Apparatus for separating solid particles from a suspension of solid particles and gas, wherein the apparatus comprises: (i) a vertical primary cyclone vessel having a tubular housing comprising of a tubular wall section provided with a tangentially arranged inlet for receiving the suspension, and a cover which closes the upper end of the tubular wall section; wherein the cover is provided with an axial circular opening which opening serves as a gas inlet opening of a gas outlet conduit; (ii) one or more secondary gas-solids cyclone separators which are fluidly connected with the gas outlet conduit of the primary cyclone.
Patent MX-PA01009675-A (MX)
Title: Method for recycling pet components and device for carrying out said method.
Inventor: KLAUS KLENK
IPC: C08G63/90
Filed: 2001-01-18
Abstract: The invention relates to a method for recycling PET flakes of disintegrated PET bottles. The flakes are subject to a washing treatment. The flakes are treated in at least one washing device at a temperature higher than 70 C and for at least 20 minutes by means of a cleaning solution containing soda lye and are also and simultaneously treated mechanically and hydraulically.
Patent MX-PA01011793-A (MX)
Title: Absorbent article with skin care composition.
Inventor: WARREN RAPHAEL
IPC: A61L15/18
Filed: 1999-05-21
Abstract: An absorbent article comprising a body contacting surface and an absorbent core is disclosed. At least a portion of the body contacting surface comprises an effective amount of a skin care composition which is solid or semisolid at 40 ¦C and which is transferable from the body contacting surface to the wearer's skin by contact, normal wearer motion and body heat at a level effective in providing a skin benefit to the wearer's skin. The skin care composition comprises from about 10 to about 95 % of an emollient and from about 5 to about 90 % of an agent capable of immobilizing the emollient. The immobilizing agent comprises a particle thickener selected from the group consisting of silica, treated silica, polymethacrylate polymers, polymethacrylate and styrene copolymers, calcium silicate, treated calcium silicate, treated bentonite, treated hectorite, and mixtures thereof.
Patent MX-PA01012126-A (MX)
Title: Mutual salt of amlodipine and atorvastatin.
Inventor: CHANG GEORGE
IPC: A61K31/40
Filed: 2000-05-08
Abstract: This invention relates to a mutual salt of amlodipine and atorvastatin, pharmaceutical compositions thereof and methods of treating angina pectoris, atherosclerosis and combined hypertension and hyperlipidemia in mammals with such a mutual salt and compositions. This invention also relates to methods of managing cardiac risk in a mammal presenting with symptoms of cardiac risk, including humans by administering such a mutual salt and compositions.
Patent MX-PA01012627-A (MX)
Title: N-alkoxyalkyl-n,n-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same.
Inventor: ONO SATOSHI
IPC: C07D277/64
Filed: 2000-06-09
Abstract: An N-alkoxyalkyl-N,N-dialkylamine derivative represented by the following general formula Ä1Ü: <CHEM> wherein the ring D represents a 5- or 6-membered heterocyclic ring or hydrocarbon ring; R<3> and R<4>, which are the same or different, represent an unsubstituted or substituted alkyl, cycloalkyl or aralkyl group; and R<1>, R<2>, R<5>, R<6>, R<7>, R<8>, m and n are as defined in the specification, or a salt thereof has an anti-hypoxic activity, a nerve-protecting activity and a nerve regeneration promoting activity and is useful for the treatment of neurodegenerative diseases.
Patent MX-PA01013460-A (MX)
Title: Topical formulations comprising skin penetration agents and the use thereof.
Inventor: VAIDYANATHAN RAJARAM
IPC: A61K6/00
Filed: 1999-09-28
Abstract: Disclosed are topical pharmaceutical compositions comprising a pharmaceutically active agent such as a corticosteroid, a diol, cetyl alcohol, glyceryl monostearate, laurocapram, stearyl alcohol, sodium lauryl sulfate and water. Also disclosed is a method for the manufacture of the compositions and methods for treating inflammatory skin conditions with the compositions.
Patent MX-PA02000391-A (MX)
Title: Lading tie anchor.
Inventor: RUDOLPH E NADHERNEY
IPC: B61D45/00
Filed: 2002-01-11
Abstract: A lading tie anchor for use in a railway boxcar having an interior metal lining, the lining having an aperture or indentation formed therein for receipt of the anchor, with the anchor comprising a one-piece body adapted to be received or seated in the opening or indentation in the metal lining. The anchor has at least two opposed edge portions that define a central opening, with the edge portions engaging the metal lining. A continuous, vertically-orientated anchoring post spans the central opening, the post including an aperture or drain hole in its lower portion to facilitate the transportation of liquid from the anchor into the aperture or indentation in the metal lining.
Patent MX-PA02002579-A (MX)
Title: Cationic liposome delivery of taxanes to angiogenic blood vessels.
Inventor: MCDONALD DONALD M
IPC: A61P17/02
Filed: 2000-09-08
Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
Patent MX-PA02003150-A (MX)
Title: Use of ribose to prevent cramping and soreness in muscles.
Inventor: BUTLER TERRI
IPC: C13B50/00
Filed: 2000-09-22
Abstract: Ribose administered before exercise reduces or prevents exercise-induced muscle cramping and soreness. Ribose taken both before and immediately after exercise further reduces or prevents exercise-induced muscle cramping and soreness.
Patent MX-PA02004594-A (MX)
Title: Urea derivatives as anti inflammatory agents.
Inventor: SANXING SUN
IPC: C07D213/40
Filed: 2000-11-16
Abstract: Disclosed are novel aromatic compounds of formula (I) wherein G, X, Ar, L and Q are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds. The compounds (I) inhibit cytokine production.
Patent MX-PA02005092-A (MX)
Title: Sulfonyl oxazole amines and their use as 5 ht6 receptor ligands.
Inventor: HARTMUT GREINER
IPC: A61P21/00
Filed: 2000-11-24
Abstract: The invention relates to compounds of the general formula (I), wherein R1 and R2 independently of one another represent H, R6, C3 C8 cycloalkyl, (CH2)n R7, (CH2)n O R6, (CH2)n NH2, (CH2)n NHR6, (CH2) N(R6)2, C2 C6 alkenyl or optionally together form a mononuclear saturated heterocycle with one or two nitrogen, oxygen and or sulphur atoms; R3 and R4 independently of one another represent H, R6, CF3, NO2, Hal, OH, O R6, NH2, NH R6, or N(R6)2; R5 represents a 5 or 6 member, saturated or unsaturated heterocycle with one or two nitrogen, oxygen and or sulphur atoms, which is optionally monosubstituted or disubstituted by R6, CF3, NO2, Hal, OH, O R6, NH2, NH R6, or N(R6)2; and R6 represents C1 C6 alkyl; R7 together with R3 and or R4 represents substituted phenyl, n represents 0 to 2. The invention also relates to the physiologically safe salts or solvates of said compounds and to the use of the compounds of the general formula (I) as medicaments.
Patent MX-PA02007173-A (MX)
Title: Calcilytic compounds.
Inventor: BURGESS JOELLE L
IPC: A61K31/565
Filed: 2001-01-24
Abstract: Novel calcilytic compounds and methods of using them are provided.
Patent MX-PA02007977-A (MX)
Title: Vaginal stimulator and device for the treatment of female urinary incontinence.
Inventor: MARTY JEAN CLAUDE
IPC: A61N1/05
Filed: 2001-02-15
Abstract: The invention relates to a programmable vaginal stimulator and to a device comprising said vaginal stimulator with a carrying and control case, without cable linking one to the other.
Patent MX-PA02009331-A (MX)
Title: Indicating lights system of the movement status of automotive vehicles.
Inventor: CARLOS SAN JUAN TORRES
IPC: G08G1/056
Filed: 2002-09-24
Abstract: Te present discloses an indicating lights system of the movement status of automotive vehicles, conformed of an electric circuit, constituted by: 2 flashers, 1 current switch and 5 current or ground relays (depending on the circuit connection) which are going to change of state, according to the different maneuvers of the driver over the braking, acceleration and change of speed mechanisms which are going to be signaled by three different color lights (red, green and yellow); said circuit is characterized for detecting, organizing hierarchically and signaling the maneuvers done by a driver; this made in different luminous signals (red, green, yellow, intermittent green and intermittent yellow), in order to let the other drivers and pedestrians know the movement status of an automotive vehicle in any given moment.
Patent MX-PA02009948-A (MX)
Title: Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoindane derivatives.
Inventor: BIGGE CHRISTOPHER FRANKLIN
IPC: A61P31/04
Filed: 2001-04-25
Abstract: The present invention provides compounds of Formula (I) and a method of treating Alzheimer s disease using a compound of Formula (I), wherein: R1 and R2 include alkyl and phenylalkyl; R3 is hydrogen or alkyl; and R4 and R5 include alkyl, alkoxy, carboxyl, alkoxycarbonyl, and nitro. Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of Formula (I) and a method of imaging amyloid deposits using compounds of Formula (I).
Patent MX-PA02012909-A (MX)
Title: Improved oral dosage formulations of 1-(5-tert-butyl -2-p-tolyl-2h-pyrazol -3-yl)-3 -[4-(2-morpholin-4 -yl-ethoxy) -naphthalen -1-yl] -urea.
Inventor: CAPPOLA MICHAEL L
IPC: A61K47/48
Filed: 2001-07-11
Abstract: A formulation comprising, and process for preparing, improved oral dosage forms of 1-(5-tert-butyl -2-p-tolyl-2H-pyrazol -3-yl)-3-[4 -(2-morpholin-4 -yl-ethoxy)-naphthalen -1-yl]-urea, a chemical entity with anti-inflammatory properties. Granulation of 1-(5-tert -butyl-2-p-tolyl -2H-pyrazol-3 -yl)-3-[4 -(2-morpholin-4 -yl-ethoxy)- naphthalen -1-yl]-urea within specified ranges provides improved dissolution of 1-(5-tert-butyl -2-p-tolyl-2H -pyrazol -3-yl)-3-[4-(2 -morpholin-4 -yl-ethoxy) -naphthalen -1-yl]-urea and oral bioavailability, as well as content uniformity. Incorporation into the formulation of an aqueous soluble inclusion compound capable of forming a complex with 1-(5-tert butyl-2-p-tolyl-2H -pyrazol -3-yl)-3-[4-(2 -morpholin-4 -yl-ethoxy) -naphthalen -1-yl]-urea, such as beta-cyclodextrin provides enhanced stability of 1-(5-tert-butyl -2-p-tolyl-2H -pyrazol -3-yl) -3-[4-(2 -morpholin-4 -yl-ethoxy) -naphthalen-1-yl] -urea, in particular in highly ionic environments. Chipping and disintegration of tablets containing more than about 10 % betacyclodextin can be prevented by applying a polymeric coat to the surface of the tablet at a temperature below 40 C.
Patent MX-PA03001155-A (MX)
Title: Teatcup liner series.
Inventor: CHOWDHURY MOFAZZAL H
IPC: A01J5/08
Filed: 2003-02-07
Abstract: A teatcup liner series, having n liners L1 through Ln, has at least one selected parameter which varies liner to liner to provide selectable milking characteristics. The teatcup liner series is produced by a cost advantaged manufacturing method.
Patent MX-PA03001498-A (MX)
Title: System for providing communication between the interior and the exterior of a compartment.
Inventor: VANDECASSERIE CHRISTIAN
IPC: B25J21/02
Filed: 2001-08-13
Abstract: A system for making a connection between the interior and exterior of a compartment, comprising a door opening through the compartment wall, a connector body which can engage with the wall, and having a connection port through it, and a removable cover on the connector body. The body is engaged with the door opening, and an inner door within the compartment engages and removes the cover. A preferred construction creates a single line of confidence seal. The system is particularly suited for sterile compartments.
Patent MX-PA03003449-A (MX)
Title: Dental impression material utilizing ruthenium catalyst.
Inventor: ANGELETAKIS CHRISTOS
IPC: A61K6/90
Filed: 2001-07-31
Abstract: A composition for use as a dental impression material including a polymerizable telechelic oligomer or polymer curable by ring-opening metathesis polymerization, a filler system, and a ruthenium carbene complex catalyst, whereby the catalyst initiates ring-opening metathesis polymerization of the composition. The invention includes a paste/paste system in which a base paste includes the polymerizable telechelic oligomer or polymer and a filler system and in which a catalyst paste includes the catalyst dissolved in an inert solvent and a filler system. The telechelic oligomer or polymer may be, for example, a polydimethylsiloxane end-functionalized with norbornenyl groups. The catalyst may be, for example, a ruthenium carbene complex with a ligand having a basicity higher than tricyclohexylphosphine. The composition of the present invention exhibits reduced sensitivity to sulfur impurities.