baber/WOPTO huggingface dataset:
Patent CA-2354134-A1 (CA)
Inventor: JAMES VERONICA
IPC: G01N33/50
Filed: 1999-12-10
Abstract: La présente invention concerne un procédé permettant, chez un patient, de détecter la présence d'un gène responsable d'un état pathologique, voire l'existence de cet état pathologique. A cet effet, on prélève sur patient au moins un poil, sur lequel on réalise une diffractométrie en fibre permettant de détecter des modifications affectant l'ultrastructure du poil. L'invention concerne également un instrument (1) permettant, chez un patient, de détecter la présence d'un gène responsable d'un état pathologique, voire l'existence de cet état pathologique, en utilisant un échantillon pileux. Cet instrument est constitué d'une source de rayons X (2) produisant un faisceau de rayons X, d'un porte-échantillon servant à présenter l'échantillon pileux (3) dans le faisceau considéré, d'un détecteur servant à détecter la diffusion du faisceau de rayons X imputable à l'échantillon pileux considéré, et d'un afficheur (9) associé au détecteur de façon à donner un affichage de la sortie du détecteur (9a, 9b, 9c et 9d). Les images que l'on obtient ainsi en sortie dénotent la présence ou non du gène, voire l'existence ou non de l'état pathologique, selon l'interprétation qui en sera faite.
Patent CA-2354557-A1 (CA)
Title: Methods to inactivate n-type calcium channels
Inventor: ZAMPONI GERALD WERNER
IPC: A61K31/202
Filed: 1999-12-17
Abstract: Compounds comprising an unbranched backbone carbon chain of 8-16C, optionally substituted at any position with 1-5 alkyl groups (1-6C) or with halo, = O, OR, SR, NR2, OOCR, NROCR, or N(OCR)2, wherein R is H, alkyl (1-6C), optionally substituted aryl (6-10C), arylalkyl (7-12C) wherein said aryl is optionally substituted, and wherein two R on the same substitutent may form a ring, or with phosphate or pyrophosphate or the alkyl (1-6C) esters thereof; and/or wherein a terminal carbon is optionally in the form of COOR -CONR2 or -COR  wherein R is H, alkyl (1-6C) or arylalkyl (7-12C); and wherein said chain may optionally contain 1-4.pi.-bonds or the epoxides thereof are useful as N-type calcium channel inactivation blockers. Libraries of these compounds can also be used to identify antagonists for other targets.
Patent CA-2357371-A1 (CA)
Title: Oxygen-enriched air feed for a non-ferrous metal production unit
Inventor: RIETH NORBERT
IPC: F25J3/04
Filed: 2001-09-13
Abstract: All of the air is compressed in a single compressor (1), which feeds the smelter (2) for smelting the ore, the converter (6) for converting the matte coming from the smelter (2) and an air separation unit (4) which delivers two oxygen streams (9, 10) for enriching the air. A buffer tank (7) is used to deliver a variable flow of enriched air to the converter (6).      Application to the production of copper.
Patent CA-2358948-A1 (CA)
Title: Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
Inventor: BOULIKAS TENI
IPC: A61K33/243
Filed: 2000-10-27
Abstract: A method for encapsulating cisplatin and other positively-charged drugs into  liposomes having a different lipid composition between their inner and outer  membrane bilayers is disclosed. The liposomes are able to reach primary tumo rs and their metastases after intravenous injection to animals and humans. The encapsulated cisplatin has a high therapeutic efficacy in eradicating a variety of solid human tumors including but not limited to breast carcinoma and prostate carcinoma. Combination of the encapsulated cisplatin with encapsulated doxorubicin or with other antineoplastic drugs are claimed to b e of therapeutic value. Also of therapeutic value in cancer eradication are claimed to be combinations of encapsulated cisplatin with a number of anticancer genes including but not limited to p53, IL-2, IL-12, angiostatin,  and oncostatin encapsulated into liposomes as well as combinations of encapsulated cisplatin with HSV-tk plus encapsulated ganciclovir.
Patent CA-2359130-A1 (CA)
Inventor: FRIESEN JED
IPC: A47K10/38
Filed: 2001-10-12
Abstract: A paper towel dispenser, which has a housing with a top, bottom and side panels. The bottom panel has a forwardly, downwardly extending rear guide panel. A cover is pivotally attached to the housing and pivotal about pins positioned at a bottom of each side of the rear guide panel so that when the cover is pivoted to an open position an entire interior of the housing is accessible. A front guide panel extends along a bottom of the cover, parallel to and spaced apart from the rear guide panel when said cover is closed. A serrated edge extends along a bottom edge of the front guide panel. A pair of roll holders are located on either side of the chassis and are operative to hold a roll of paper and to permit it to be rolled in response to a pulling force on an end of the paper.
Patent CA-2359249-A1 (CA)
Inventor: BEAUMONT FRANCOIS
IPC: B65G17/30
Filed: 2001-10-18
Abstract: A load gripping conveyor that is especially useful for carrying pieces of meat to be processed includes input and output end rotors around which is mounted an endless carrier belt defining a conveying forward span, and at least gripper device connected to the inner surface of the belt which includes in main lever member provided with a hook and being pivotally connected to the belt inner surface at a first location thereon about a main pivot axis. The gripper device further includes a link assembly having a leading end connected to the main lever member and a trailing end connected to the belt inner surface at a second location thereon downstream from the first location. Operation???, the link assembly cooperates with the input rotor upon rotation thereof from a load receiving position wherein the hook protrudes outwardly through an opening provided on the belt to a load gripping position wherein the hook moves inwardly toward the belt structure outer surface for gripping the load thereon a first embodiment of the load gripping conveyor employs link assembly formed by a head link member pivotally connected to a tail link member, a second embodiment employs a head link member pivotally connected to a tail link member through one or more intermediate lever members. A third embodiment employs link assembly formed of an elongated spring band.
Patent CA-2359356-A1 (CA)
Inventor: ZEITOUNE-SIMOVICH SYLVIA
IPC: C12N15/82
Filed: 2000-01-16
Abstract: The invention relates to an expression-silencing system comprising a first DNA  construct comprising a nucleotide sequence corresponding to the T7 RNA  polymerase gene (T7-pol) which carries an NLS sequence, and at least one promoter and at least one terminator sequence operably linked to the T7-pol; a second DNA construct comprising a T7 promoter sequence (pT7), at least one targeting sequence downstream to said pT7 and at least one 3' non-translated terminator sequence operably linked to the targeting sequence; which system can, upon its introduction into a cell, substantially silence the expression at the RNA level of a target sequence in the cell, in a tissue or organ regenerated from said cell, or in a progeny thereof, substantially silenced, by causing the substantial disappearance of the RNA or RNA transcript carrying said sequence or a functional part thereof.
Patent CA-2360257-A1 (CA)
Inventor: LAY ROGER F
IPC: G01B17/00
Filed: 2000-01-19
Abstract: Dans une de ses réalisations préférées, l'invention concerne un distributeur de ruban d'étanchéité à commande électronique (20, Fig. 1) comportant un logement (30, Fig. 1), un dispositif (32, Fig. 1) disposé dans le logement (30, Fig. 1) et permettant la sélection d'une première longueur choisie de ruban d'étanchéité (70, Fig. 2) et un appareil électronique (120, Fig. 4) conçu pour distribuer la première longueur sélectionnée de ruban d'étanchéité (70, Fig. 4).
Patent CA-2361565-A1 (CA)
Title: Synthesis of ethyleneimine dimer
Inventor: PLUNKETT KEVIN S
IPC: C07C403/04
Filed: 2000-01-28
Abstract: The invention provides a method to synthesizing ethyleneimine dimer. This method of synthesis provides several advantages over previous methods: (1) the starting compounds are all relatively inexpensive, (2) the yield of product is greater than 20 % of the theoretical yield; and (3) the steps of synthesis are easy, inexpensive and amenable to large-scale production. All of these advantages allow for less expensive production of ethyleneimine dimer.
Patent CA-2362189-A1 (CA)
Title: Filter element having a handle
Inventor: TOKAR JOSEPH C
IPC: B01D46/10
Filed: 2000-02-23
Abstract: A filter arrangement includes a filter element configured for straight throu gh flow and a handle member secured to the filter element. The filter element m ay typically have a plurality of flutes where selected ones of the flutes are open at upstream portions and closed at downstream portions, and where selected ones of the flutes are closed at the upstream portions and open at the downstream portions. In one embodiment, the handle member is secured to the central core member. In some embodiments, the handle member and the central core member are a single molded construction. The handle member can include a single aperture, such as an elongated slot, or a plurality of apertures. A method for servicing a system having a straight through flow filter element includes grasping a handle secured to the filter element, and  pulling the handle to remove the filter element from the system.
Patent CA-2362401-A1 (CA)
Inventor: SHIOSAKI KAZUMI
IPC: C07C233/75
Filed: 2000-02-03
Abstract: G-protein coupled heptahelical binding compounds are described, e.g. compounds of the formula (I): J-M wherein J is an aromatic moiety and M is a G-protein coupled heptahelical receptor pocket interacting moiety. The compounds of the invention can be used to treat chemokine mediated disorders, e.g.  neurological, immunological, inflammatory and cancer related disorders.
Patent CA-2365491-A1 (CA)
Inventor: ZIFF SUSAN J
IPC: G06Q10/10
Filed: 2000-03-17
Abstract: L'invention concerne un système et un procédé de gestion de flux de travaux associés à la création d'un scénario, permettant d'augmenter la vitesse, le contrôle qualitatif et la précision, et réduisant le coût du processus de création d'un scénario, en fournissant les étapes de ce processus en un seul système intégré. Ce système permet également aux utilisateurs de travailler à différents moments de la journée et dans différents emplacements géographiques, et il leur permet encore de déterminer rapidement l'état actuel de n'importe quel scénario du système.
Patent CA-2365898-A1 (CA)
Inventor: SUTTON CHRISTOPHER
IPC: A61P29/00
Filed: 2000-04-28
Abstract: L'invention concerne une séquence d'acides nucléiques et d'acides aminés des nouveaux polypeptides I-1 et I-2, qui sont associés aux affections intestinales inflammatoires humaines. L'invention concerne également des procédés pour le diagnostic et le traitement des affections intestinales inflammatoires à l'aide des antigènes I-1 et I-2 associés à ces affections.
Patent CA-2367624-A1 (CA)
Title: Telephone wiring interconnect apparatus and method
Inventor: VO CHANH C
IPC: H01R24/58
Filed: 2002-01-15
Abstract: An interconnect apparatus for electrically connecting Telco wires to subscriber wires is arranged and configured to withstand overcurrent and overvoltage conditions. The interconnect apparatus includes a jack, a first set of contacts, and a first set of by-pass conductors. The first set of by-pass conductors is electrically connected to the first set of contacts and has a greater current carrying capacity than the first set of contacts. The interconnect apparatus further includes a second set of by-pass conductors and a plug. The second set of by-pass conductors is electrically connected to the first set of by-pass conductors when the plug and jack are engaged. The second set of by-pass conductors may also have a greater current carrying capacity than the first set of contacts.  Preferably, the first set of by-pass conductors is spaced sufficiently apart and the second set of by-pass conductors is spaced sufficiently apart to substantially eliminate arcing.
Patent CA-2373722-A1 (CA)
Title: Telephone which enables timely input and presentation of information
Inventor: MATSUMOTO FUMIAKI
IPC: H04W4/16
Filed: 2002-02-27
Abstract: A telephone includes: a reminding unit for, when judging that a user makes a call but fails to convey information to a party, reminding the user to input the information into information acceptance unit; the information acceptance unit for accepting input of the information from the user; a storage unit for associating the inputted information with a telephone number of the party and storing the associated information; and a notification unit for, when the user makes a call to the party or receives a call from the party, checking whether the information associated with the telephone number of the party is stored in the storage unit, and, if the associated information is stored therein, notifying the user of the stored information.
Patent CA-2373791-A1 (CA)
Title: Closure device
Inventor: STIGLIC JEFFREY S
IPC: A44B19/16
Filed: 1999-06-10
Abstract: The closure device (121) includes interlocking fastening strips (130, 131) and a slider (132) slidably disposed on the fastening strips for facilitating the occlusion and deocclusion of the fastening strips when moved towards first and second ends thereof. Flexible shoulders (230, 232) and legs (234, 236) are disposed on the slider (132) for facilitating the attachment of the slider onto the fastening strips (130, 131) in the vertical Z axis (106). The flexible shoulders (230, 232) and legs (234, 236) further provide resistance against the removal of the slider (132) from the fastening strips (130, 131) in the vertical Z axis (106) thereafter.
Patent CA-2374426-A1 (CA)
Title: Contact support for cycle safety device
Inventor: GAUTIER GERARD
IPC: B62J6/04
Filed: 2001-03-22
Abstract: The invention concerns contact support designed to be mounted on a cycle brake-control cable (2), said support (1) comprising a first part (3), fixed relative to the cycle frame, said fixed part (3) having a first contact surface (4); a second part (5), mobile relative to the cycle frame, and secured to the cable (2), said mobile part (5) having a second contact surface (6). The invention is characterised in that it comprises linking means (7) between the fixed part (3) and the mobile part (5), said linking means (7) being elastically deformable between an extreme loose state for the support (1), wherein the contact surfaces (4, 6) are spaced apart from each other, and a tensioned state for the support (1) wherein the contact surfaces (4, 6) are pressed against each other, the linking means (7) being then elastically deformed.
Patent CA-2379009-A1 (CA)
Inventor: RONALD TIMOTHY R
IPC: H01M10/052
Filed: 2002-03-27
Abstract: A power providing device that has a battery, a protective housing a terminal cap, and a fuse on a substrate.
Patent CA-2380379-A1 (CA)
Title: Procede d'electrofusion selective d'au moins deux partenaires de fusion ayant des membranes de type cellules
Inventor: ORWAR OWE
IPC: C12N15/02
Filed: 2000-07-13
Abstract: L'invention concerne un procédé d'électrofusion sélective d'au moins deux partenaires de fusion ayant des membranes de type cellules et de dimensions cellulaires ou subcellulaires consistant a) à mettre les deux partenaires de fusion en contact et b) à fournir un champ électrique d'une force suffisante pour obtenir la fusion et très focalisé sur les partenaires de fusion. Ceux-ci sont sélectionnés dans le groupe constitué d'une seule cellule, d'un liposome, d'un protéoliposome, d'une vésicule synthétique, d'une cellule d'oeuf, d'une cellule d'oeuf énuclée, d'une cellule de sperme à un stade quelconque de développement et d'un protoplaste de plante.
Patent CA-2380708-A1 (CA)
Inventor: LEE JOHN RANDY
IPC: B64D43/00
Filed: 2002-04-17
Abstract: An instrumentation panel has a panel display surface and an opposed surface , with an interconnected web of raised material lands arranged across the display surface of the panel and which display surface is otherwise generally characterized by interstitial depressions, and wherein the display surface lands are adapted to receive at least one instrumentation housing in fixed-supported relation there through. In one embodiment, the opposed surface also comprises a plurality of raised complementary lands, preferably arranged in a transverse intersecting pattern relative to the pattern of the raised lands of the display surface. In another embodiment, the lands form a pattern that provides visual cues that aid the viewer in rapidly centering the instrumentation within the visual field and preferably, the lands and the depressions an the display surface receive respective but mutually visually contrasting surface treatments.
Patent CA-2381738-A1 (CA)
Title: Method of fabricating muntin bars for simulated divided lite windows
Inventor: REICHERT GERHARD
IPC: E06B3/66
Filed: 2000-08-11
Abstract: A method for fabricating muntin grid pieces includes steps that attach a pair of material strips to opposed edges of the muntin bar element. The material strips may be provided in side-by-side strips that may be separated and simultaneously applied to the opposite sides of the muntin bar element. The connection between the material strips and the muntin bar element may be made with an adhesive or a mechanical connection. The method allows the material strips to be connected to the muntin grid pieces before the muntin grid pieces are assembled into a muntin bar grid for a window.
Patent CA-2383138-A1 (CA)
Title: System and method for detecting the state of hydration
Inventor: EYAL-BICKELS ELAZAR
IPC: A61B5/053
Filed: 2000-09-21
Abstract: The invention provides a system (2) for non-invasive detection of the state of hydration in a living specimen, the system including an RF generator/transmitter (416) for emitting RF radiation signals and for transmitting the radiation signals through a tissue of a living specimen; an RF receiver (8) for receiving RF signals transmitted through the tissue, and for feeding the signals to a processor (10) for comparison of relative attenuation of RF frequencies passing through the tissue with a reference attenuation ratio signal, and an indicator unit (12) for providing an output signal representative of the water content level of the tissue. A method for non-invasive detection of the state of hydration in a living specimen is also described and claimed.
Patent CA-2385853-A1 (CA)
Title: Design of high affinity rnase h recruiting oligonucleotide
Inventor: JAKOBSEN MOGENS HAVSTEEN
IPC: A61K31/7084
Filed: 2000-10-03
Abstract: The present invention relates to the field of bicyclic DNA analogues, e.g. LNA  and LNA modifications, which are useful for designing oligomers that form high affinity duplexes with complementary RNA wherein said duplexes are substrates for RNase H. The oligonucleotides may be partially or fully composed of LNA  analogues with very high affinity and ability to recruit RNase H. The implications are that oxy-LNA by itself may be used to construct novel antisense molecules with enhanced biological activity. Alternatively, oxy-LNA  may be used in combination with non-oxy-LNA, such as standard DNA, RNA or other analogues, e.g. thio-LNA or amino-LNA, to create high affinity, RNase H  recruiting anti-sense compounds without the need to adhere to any fixed design.
Patent CA-2386007-A1 (CA)
Title: System and device for preventing restenosis in body vessels
Inventor: KESTER MARK
IPC: A61F2/82
Filed: 2000-10-05
Abstract: The present invention relates to a system and device for preventing stenosis  and/or restenosis after an invasive procedure in a body vessel or cavity having an inner wall surface, the system comprising inserting a device coate d with a growth arresting, lipid-derived, bioactive substance at a desired location along the inner wall surface of the body vessel or cavity.
Patent CA-2387006-A1 (CA)
Title: A novel mouse with deficiency of gene of neutrophil chemotactic factor lect2
Inventor: SUZUKI KAZUO
IPC: C12N15/09
Filed: 2002-05-17
Abstract: This invention relates to a mouse with deficiency of gene of neutrophil chemotactic factor LECT2 having a function of lacking by deleting a whole or a part LECT2 gene or inserting other gene such as a selective marker gene to any portion of the gene or LECT2 gene replacing with other gene(s).
Patent CA-2396732-A1 (CA)
Title: Catalyst and adsorption composition
Inventor: HECK RONALD M
IPC: B01D53/74
Filed: 2001-01-16
Abstract: A mixture comprising a first material selected from the group consisting of a catalyst composition and an adsorbent composition and a second material selected from the group consisting of clays and silicone polymers. A method for improving the adhesion of the said first material to a metal surface, where the method involves adding the said second material to the said first material before coating the metal surface with the resultant mixture. In a preferred embodiment, the metal surface is the exterior surface of an automobile radiator.
Patent CA-2403608-A1 (CA)
Title: Utilisation de fulvestrant dans le traitement du cancer resistant du sein
Inventor: THURLIMANN BEAT
IPC: A61P35/00
Filed: 2001-04-02
Abstract: L'invention concerne l'utilisation de fulvestrant dans le traitement du cancer du sein chez des patients ayant préalablement été traités par un modulateur sélectif des récepteurs d'oestrogènes (SERM) et un inhibiteur d'aromatase.
Patent CA-2405412-A1 (CA)
Inventor: FAVIS REYNA
IPC: C12Q1/6837
Filed: 2001-04-04
Abstract: The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural  capture oligonucleotide probes have melting temperatures within a narrow range. The first step of the method involves providing a first set of a plurality of tetramers of four nucleotides linked together, where (1) each tetramer within the set differs from all other tetramers in the set by at least two nucleotide bases, (2) no two tetramers within a set are complementary to one another, (3) no tetramers within a set are palindromic or dinucleotide repeats, and (4) no tetramer within a set has one or less or three or more G or C nucleotides. Groups of 2 to 4 of the tetramers from the  first set are linked together to form a collection of multimer units. From t he collection of multimer units, all multimer units formed from the same tetram er and all multimer units having a melting temperature in ~C of less than 4 tim es the number of tetramers forming a multimer unit are removed to form a modifi ed collection of multimer units. The modified collection of multimer units is arranged in a list in order of melting temperature. The order of the modifie d collection of multimer units is randomized in 2~C increments of melting temperature.
Patent CA-2410834-A1 (CA)
Title: Vertical retractable blind
Inventor: NIEN MING
IPC: E06B9/32
Filed: 2002-11-01
Abstract: A vertical retractable blind is constructed to include a fixed headrail, a lifting rail vertically movable in horizontal below the headrail, two positioning cords adapted to support the lifting rail at the desired elevation. The positioning cords each have a first end connected to the headrail and a second end respectively extended across the lifting rail and fixedly secured to a respective fixed point outside the lifting rail to provide a tension force to the lifting rail. A retractable blind body is connected between the headrail and the lifting rail and vertically extended out/received subject to vertical movement of the lifting rail.