baber/WOPTO huggingface dataset:
Patent FI-981521-A0 (FI)
Inventor: AHO PAEIVI
IPC: A61P11/00
Filed: 1998-07-01
Abstract: The invention relates to the compounds of formula I:wherein one of X1 and X2 is MeSO2 and the other one is hydrogen or halogen and X3 is hydrogen or halogen. These compounds have been found to be useful in the prevention and the treatment of respiratory diseases, especially asthma, ARDS (Acute Respiratory Distress Syndrome), COPD (chronic obstructive pulmonary diseases), allergic rhinitis and related inflammatory conditions. More specifically, the invention relates to the use of said compound in the prevention and the treatment of asthma in steroid-resistant patients. The invention also relates to pharmaceutical formulations used in the treatment of said diseases.
Patent FI-981987-A0 (FI)
Inventor: VIITA-AHO TARVO
IPC: B66B11/00
Filed: 1998-09-15
Abstract: Elevator arrangement comprising an elevator shaft (1), at least one guide rail (2) extending vertically in the elevator shaft, a car (3) guided by the guide rail and moving in the shaft, a counterweight (4) and an elevator machine (5) with an elevator rope (6) and diverting pulleys (7, 8) for moving the car and counterweight, the elevator machine being mounted on the guide rail. According to the invention, the elevator arrangement comprises an auxiliary support (9) separate from the guide rail (2) and placed between the elevator shaft and the elevator machine, the weight of the elevator machine (5) being partially applied to the auxiliary support.
Patent IL-59052-A0 (IL)
Title: Hexahydro-1,4-oxazepine derivatives their preparation and pharmaceutical compositions containing them
IPC: A61K31/55
Filed: 1979-12-28
Abstract: Novel hexahydro-1,4-oxazepines of the general formula I    <IMAGE>  I where R1 is hydrogen, or alkyl or acyl each of 1 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms and R3 and R4 are identical or different and each is hydrogen or methyl, and their salts with physiologically acceptable acids, processes for their preparation, drugs which contain these compounds, and their use in therapy. The compounds may be used for the pharmacotherapy of pain of various geneses.
Patent IL-59614-A0 (IL)
Title: Penicillins and their salts,their preparation and pharmaceutical compositions containng them
IPC: C07D499/70
Filed: 1980-03-14
Abstract: Compounds of the formula   <IMAGE>  and  <IMAGE>  wherein A is phenyl, p-hydroxy-phenyl, 2-thienyl, 3-thienyl or 3,4-disubstituted phenyl, where the substituents, which may be identical to or different from each other, are each chlorine, hydroxyl or methoxy; R is -NH-Z-X; Z is straight or branched alkylene of 1 to 6 carbon atoms or cycloalkylene of 3 to 6 carbon atoms; X is cyano, hydroxyl, mercapto, aminocarbonyl, aminosulfonyl,   <IMAGE>  <IMAGE> +TR OR1, OCOR1, SR1, SOR1 or SO2R1;   R1 is straight or branched alkyl of 1 to 4 carbon atoms or phenyl;  R2 is hydrogen or alkyl of 1 to 4 carbon atoms; and  R1 and R2, together with an adjacent nitrogen atom to which they are attached, form a 3- to 6-membered heterocyclic ring; and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases.
Patent IL-86751-A0 (IL)
Title: Cyclosporins and pharmaceutical compositions containing them
IPC: A61P29/00
Filed: 1988-06-15
Abstract: Cyclosporins wherein the residue at the 1-position (typically -MeBmt- or -dihydro-MeBmt-) is 3 min O-acylated or 3 min -oxo or -C1-4alkoxyimino substituted, or wherein the residue at the 2-position is  beta -O-acyl or  beta -oxo substituted, or wherein the residue at the 2-position is -Ile-, or wherein the residue at the 11-position is -MeAla-, -MeIle- or -MealloIle- as well as various naturally occurring cyclosporins/dihydro-derivatives thereof, are useful in reversing resistance to chemotherapy, in particular resistance to cytostatic or anti-neoplastic therapy. Various of these cyclosporins and intermediates for their production are novel. Intermediates wherein the residue (e.g. -MeBmt-, -dihydro-MeBmt- etc.) at the 1-position is 8 min -alkoxy of 7 min -desmethyl-7 min -hydrocarbyl substituted are novel and useful as immunosuppressants, anti-inflammatory and anti-parasitic agents.
Patent IL-86985-A0 (IL)
Title: Hazardous material vial apparatus providing expansible sealed and filter vented chambers and method
IPC: A61J1/00
Filed: 1988-07-04
Abstract: A method of utilizing an apparatus of the type comprising a vial container hazardous material in the vial container in a condition requiring a diluent to be mixed therewith to form the liquid solution, and an assemblage carried by the vial container for providing (1) a sealed medicament chamber within the vial container within which the hazardous material is disposed, (2) a filter vented control chamber and (3) a sealed variable volume control chamber between the vented control chamber and the medicament chamber. The method is such as to enable an open end of a syringe needle of a diluent syringe having a syringe chamber containing diluent in communication therewith to be moved into and withdrawn successively from the chambers so as to mix the diluent with the hazardous material. The method also contemplates procedures for separately refilling a dosage syringe and for relieving any residual pressure in the vial chamber with the use of an empty syringe prior to initial or final refilling of a dosage syringe. The reconstituting, pressure relief and/or refilling procedures all being performed in such a way as to substantially prevent the hazardous material from entering the immediate atmospheric environment.
Patent IL-89378-A0 (IL)
Title: Pharmaceutical granulate having improved flow properties
IPC: A61K9/20
Filed: 1989-02-22
Abstract: A wet granulate is provided containing a therapeutically useful substance having a water solubility 10 wt% or less and microcrystalline or microfine cellulose or a mixture of both, characterised in that substantial amounts of wet binders are avoided.   Tableting mixtures with the new granulate possess a good flow pattern and may be compressed to tablets which show an excellent disintegration behaviour.
Patent IL-97648-A0 (IL)
Title: Stabilized 4-ethyl-2-hydroxyimino-5-nitro-3-hexenamide pharmaceutical compositions and methods for the preparation thereof
IPC: A61K47/12
Filed: 1991-03-22
Abstract: A stabilizer for 4-ethyl-2-hydroxyimino-5-nitro-3-hexenamide represented by the following chemical formula (I) or a salt thereof acceptable as drug or drug containing as pharmacologically active ingredient a compound represented by a chemical formula (I) , in particular, (+/- )-(E)-4-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide or salt/s thereof acceptable as drugs, a stabilizing method by the use thereof and drugs containing such stabilizer and stabilized thereby. <CHEM> s
Patent AU-PO425696-A0 (AU)
Title: A device for preventing or reducing the passage of air through the mouth
IPC: A61M16/06
Filed: 1996-12-18
Abstract: A device (20) for preventing or reducing the passage of air through the mouth (22). The device (20) comprises a top lip member (26) and a bottom lip member (28) having a space (34) therebetween. The space (34) is configured such that, in use, when the top and bottom lips (22T & 22B) of a patient are forced through the space (34), the top and bottom lip members (26 & 28) squeeze the top and bottom lips (22T & 22B) together thereby substantially sealing the mouth (22).
Patent AU-PQ196199-A0 (AU)
Title: Internal quality control
IPC: G01N21/78
Filed: 1999-08-02
Abstract: Methods for providing a population of bioparticles, modifying the bioparticles to permanently and detectably tag each bioparticle to give tagged bioparticles, forming an internal quality control sample of a defined quanta of tagged bioparticles in a defined volume of carrier, adding the control sample to an assay sample for the detection of the same bioparticles, carrying out said assay, and thereafter determining the proportions of tagged bioparticles so detected in the assay sample as a measure of assay accuracy are described. Also described are methods for providing an internal quality control in the analysis of bioparticles in potable fluids, and internal quality control standards.
Patent FI-20031185-A0 (FI)
Inventor: LAAKSO TAUNO
IPC: D21D/
Filed: 2003-08-22
Abstract: A method is provided for manufacturing a screen cylinder, as well as a screen cylinder with screen wires in the axial direction of the screen cylinder set at predefined intervals into a cylindrical screen surface and fastened to support rods, with end rings are arranged at the ends of the screen cylinder. At least one end ring is mounted at one end of the screen cylinder in such a manner that the end ring is arranged to at least one support rod at the ends of the screen wires or closest to the ends of the screen wires without fastening the end ring to the screen wires. When installing the end ring, a shrink fit is formed between the end ring and support rod, wherein the end ring is arranged to press the support rod substantially perpendicular to the axis of the screen cylinder.
Patent FI-20115153-A0 (FI)
Inventor: SUORSA ILKKA
IPC: H02M/
Filed: 2011-02-17
Abstract: A switched-mode power supply comprises a transformer with a primary winding and a secondary winding. A switch is coupled in series with the primary winding and configured to repeatedly interrupt a current through the primary winding. An inductor is located differently with reference to magnetic fields that the primary and secondary windings are configured to induce. A connection exists between the inductor and a circuit that contains one of the primary and secondary windings. The connection is configured to connect from the inductor to the circuit a first voltage that has a waveform representative of and a polarity opposite to a second voltage induced in the switched-mode power supply by leakage flux of the transformer at a switching moment of the switch.
Patent IL-105519-A0 (IL)
Title: Labelled fibrinogen receptor antagonists,their preparation and their use
IPC: C07D235/18
Filed: 1993-04-27
Abstract: The present invention relates to novel fibrinogen receptor antagonists labelled with a detectable atom, which have a comparable or higher affinity for the receptor than <125>I-fibrinogen and whose binding is not impaired by foreign proteins, in particular the tritium-labelled fibrinogen receptor antagonists according to Claim 3 which, in the presence of foreign protein, e.g. of albumin or of fibrinogen, have an affinity (KD) of less than 500 nM for the receptor, their use as ligands in the fibrinogen receptor binding test or for determination of the concentration of fibrinogen receptor antagonists, and to processes for their production.
Patent IL-110323-A0 (IL)
Title: Lens mold
IPC: B29C33/38
Filed: 1994-07-14
Abstract: A lens mold includes first (1) and second mold (2) members respectively having a concave (3) surface and a convex surface (4) for defining therebetween a lens cavity. One of the first and second mold members is configured to mechanically engage a ring of excess lens material upon polymerization of the lens material. Alternately, one of the first and second mold members includes a material formed along the periphery of a lens cavity (5) which causes the ring of excess lens material thereto. Furthermore, one of the first and second mold members is formed of a relatively transparent plastic material and includes an outer surface having an optical finish to permit optical inspection of a lens located on one of the concave and convex surfaces. Alternately, one of the first and second mold members is formed of a relatively opaque plastic material and includes an inner surface having an optical finish to permit optical inspection of a lens located on one of the concave and convex surfaces. <IMAGE>
Patent IL-112269-A0 (IL)
Title: Polymer blend and its use for transdermal drug delivery
IPC: A61K9/70
Filed: 1995-01-08
Abstract: A blend of at least three polymers, including a soluble polyvinylpyrrolidone, in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. Soluble polyvinylpyrrolidone increases the solubility of drug without negatively affecting the adhesivity of the composition or the rate of drug delivery from the pressure-sensitive adhesive composition <IMAGE>
Patent IL-129855-A0 (IL)
Title: Bovine lactation associated immunotropic protein (CD14) encoding gene and application in B cell activation
IPC: A61P43/00
Filed: 1997-11-18
Abstract: A protein purified from bovine colostral whey and isolated nucleotide sequences encoding the protein is identified. The isolated bovine protein is termed Bovine Lactation Associated Immunotropic (Bo-LAIT) protein. The human homologue of Bo-LAIT protein, Hu-LAIT protein, is also described. A method of activating B cells, and particularly of activating B cells in a mammal, such as a human, in need of such activation by administering LAIT protein is described. LAIT protein can be incorporated into infant formula. LAIT protein can be administered to an infant, as by feeding to the infant such formula. LAIT protein can incorporated as part of a vaccination. LAIT protein can administered to a patient having a T cell immune deficiency, for example, a particular T cell dysfunction in which gp39 (CD40L) is under expressed an or totally absent from the cell surface of patient T cells. Preparation of medicaments including LAIT protein for activating B cells in a mammal in need of such activation is described. Natural or recombinant LAIT protein can be used.
Patent IL-130714-A0 (IL)
Title: Dosage forms and method for ameliorating male erectile dysfunction
IPC: A61K31/568
Filed: 1998-01-16
Abstract: The present invention discloses the use of a pharmaceutical composition for oral administration comprising a carrier and active ingredient selected from a dopamine agonist, testosterone and mixtures thereof, the composition being in the form of a fast-dispersing dosage form designed to release the active ingredient rapidly in the oral cavity for the manufacture of a medicament for treatment of male erectile dysfunction.
Patent IL-131100-A0 (IL)
Title: Device for laser writing on materials
IPC: B41J3/28
Filed: 1998-02-06
Abstract: A device for inscribing materials has a hand-held device and a support device. The devices have a laser, a refraction unit, a control unit and a power pack consisting of compact, transportable components. The devices are connected to one another by means of a cable or glass fiber connection.
Patent IL-146922-A0 (IL)
Title: Release mechanism in missile
IPC: F15B15/19
Filed: 2000-06-02
Abstract: A release mechanism between a projectile and a rocket motor in a missile. The projectile releases from the rocket motor during flight of the missile when the rocket motor burns out and aerodynamic retardation commences. The front end of the rocket motor comprises a forward closure, a lock retainer received and movable within the forward closure, at least one lock, at least one spring that biases the lock against the lock retainer in a direction opposite the to the direction of motion of the missile. The rear end of the projectile has a central boss surrounded by the forward closure of the rocket motor, wherein the boss comprises recesses or a circumferential groove in which the at least one lock lies and keeps the forward closure and the boss axially together.
Patent IL-147357-A0 (IL)
Title: Fault detection in a micro electro-mechanical device
IPC: B41J2/015
Filed: 2000-05-24
Abstract: A printing nozzle arrangement is provided having an electrical current source, a fluid chamber having a fluid inlet and fluid ejection port, a heating element within the chamber electrically connected to the electrical current source, and a microprocessor. The heating element is configured such that electrical current applied by the electrical current source at a predetermined energy level causes resistive heating and ejection of the fluid from the fluid ejection port. The microprocessor is configured to test for faulty operation of the heating element by causing application of electrical current for a predetermined duration which does not result in fluid ejection. When faulty operation is determined, the microprocessor is configured to cause application of electrical current at an energy level significantly greater than the predetermined energy level in an attempt to clear fluid blockages associated with the chamber.
Patent IL-147369-A0 (IL)
Title: Cyclosporin-containing preparations
IPC: A61K47/08
Filed: 2001-12-27
Abstract: A composition (A) comprises: (a) cyclosporin (I) as active ingredient; (b) polyethylene glycol (PEG) and/or propylene carbonate (PC); (c) an oil component consisting of a mixture of an esterified compound of fatty acid and primary alcohol, and fatty acid monoglyceride; and (d) a surfactant (HLB value 8-17). Also claimed is the preparation of the composition comprising: (i) mixing (b), (c) and (d); (ii) adding (a) with stirring and heating to 60[deg]C; and optionally (iii) encapsulating the concentrate into a gelatin shell soft capsule containing PEG and propylene glycol as the plasticiser, followed by air cooling.
Patent IL-148942-A0 (IL)
Title: C-peptide for the improved production of insulin and insulin analogues
IPC: C12N15/17
Filed: 2000-09-15
Abstract: The invention relates to a precursor of human insulin or of an insulin analog of the formula I:whereinFus is an optionally present fusion portion;B(1-30) is a B chain of human insulin,Y is an amino acid chain which terminates with a basic amino acid at the C terminus;n is from 2 to 50 and indicates the length of the amino acid chain Y; andA(1-21) is an A chain of human insulin,and the A chain and/or the B chain can be modified by amino acid substitution, deletions and/or additions. The present invention also provides DNA coding for the above precursors, preparation and use of the instant precursors and DNA, and a process for preparing human insulin or an insulin analog.
Patent IL-152009-A0 (IL)
Title: Fungicidal active ingredient combinations
IPC: A01N59/20
Filed: 2001-04-09
Abstract: The invention relates to novel fungicidally active compound combinations of (a) methoximinoacetamide derivatives of the general formula (I), in which R<1 >represents unsubstituted or fluorine-, chlorine-, bromine-, methyl-, ethyl-, n- or i-propyl-, n-, i- or t-butyl-, methoxy-, ethoxy-, or phenoxy-substituted phenyl, 2-naphthyl, 1,2,3,4-tetrahydronaphthyl, indanyl, 2-benzofuranyl, 2-benzothienyl, 2-thienyl, or 2-furanyl, and (b) other active compound groups listed in the disclosure.
Patent RO-129442-A0 (RO)
Title: Crawler minirobot with electric actuation from collected solar energy and with attached explosive charge
Inventor: PETRIŞOR SILVIU MIHAI
IPC: B25J9/02
Filed: 2013-09-16
Abstract: The invention relates to an automotive crawler minirobot for sapper applications, which is electrically actuated with the energy obtained from some solar cells embedded into three solar panels attached to the metallic structure of the minirobot and is provided with a compartment storing the explosive charge needed for mine clearance and for neutralizing unexploded ammunition and improvised explosive devices. According to the invention, the minirobot comprises two main modules: a rotation module () and a modular robotic arm, each of them having at least one mobility degree, as well as a basic minirobot module () where the rotation module () consists of a rotation coupling () having a cylindrical surface and a rotation plate () and where the modular robotic arm has an open-chain serial construction and consists of two arms () and a third arm () for orienting and positioning purposes, provided with a gripping device () having sliding gripping fingers which exhibit a pivoting joint articulation, the minirobot being actuated as follows: motion and direction are achieved by some stepped motors (), the coupling () and the robotic arm are rotated by another stepped motor (), while the rotation of the arms () is achieved by other three stepped motors () and a last stepped motor () provides the pivoting of the fingers within the structure of the gripping device (), all the said actuation motors being supplied during the day time from the solar cells embedded into two panels () and during the night time from some secondary batteries charged from the third panel ().
Patent RO-132097-A0 (RO)
Title: Plant and process for treating water for drinking purposes
Inventor: MANEA FLORICA
IPC: C02F1/44
Filed: 2016-12-05
Abstract: The invention relates to a plant and a process for treating water for drinking purposes. According to the invention, the plant uses a modular system consisting of an electrolyser (6) with boron-doped diamond electrodes (7), supplied with raw water by a pump (1), wherein NaCl is optionally dosed through a tank (4), to be mixed with the raw water in a mixing valve (2) and passed through a flow-control device (5), and the electrolysis-treated water controlled by a discharge nozzle (8), is passed, in 30% ratio, through a pipe (9), through a pump (10), into a reverse osmosis unit (11), wherefrom, through a pipe (12), gets into a storing tank (14) together with the rest of electrolysis-treated water passed through a pipe (13) from where the treated drinking water is distributed through a pipe (15). As claimed by the invention, the process which uses the treating plant is performed according to the following stages: NaCl is dosed to provide optimal operation conditions of the electrolyser, the water is passed through the electrolyser with boron-doped diamond electrodes, the water flow supplying the electrolyser is controlled to ensure the water continuous presence in the electrolyser, the electrolyser operation in galvanostatic conditions is enabled at a current density of minimum 25 mAcmwhile reversing the polarity applied every 10 minutes of electrolysis, after which the water quality evaluating parameters are controlled: organic load, ammonium, nitrite, nitrate, chloride and sodium, and, in the end, the storing tank is supplied with the electrolysis-treated water mixed with water subjected to reverse osmosis.
Patent AP-2002002596-A0 (AP)
Title: Piperazine and piperidine derivatives.
Inventor: TOMLINSON Ronald Mr
IPC: C07D211/62
Filed: 2001-02-09
Abstract: The present invention relates to piperazine and piperidine derivatives, which are especially useful for treating or preventing neuronal damage, particularly damage asssociated with neurological diseases. These compounds are also useful for stimulating nerve growth. The invention also provides compositions comprising the compounds of the present invention and methods of utilizing those compositions for treating or preventing neuronal damage or for stimulating nerve growth.
Patent ZW-6294-A1 (ZW)
Title: Improved mould for steel continuous casting, particularly for the continuous casting of thin slabs.
Inventor: ARVEDI GIOVANNI
IPC: B22D11/04
Filed: 1994-05-17
Abstract: An improved mould, particularly suitable for the continuous casting of thin slabs, shows the wide walls having a profile in a vertical plane being formed of a number of curved lines which are radiused to each other, in particular arcs of circumference having a bending radius of a size decreasing downward from a value approaching infinity on the inlet side where the tangent line to the profile is vertical, until reaching with a continuous line the known lower band at the outlet from the mould. The latter is an arc of circumference with the center in the oscillating center of mould, being positioned at a height comprised between the levels of inlet and outlet sides of the mould itself. Preferably the profile pattern is elliptical starting from the inlet side with vertical tangent down to said lower arc of circumference, so that the bending variation is caused to be tendentially continuous.