baber/WOPTO huggingface dataset:
Patent CA-3053993-A1 (CA)
Inventor: WINQVIST OLA
IPC: A61K31/7052
Filed: 2018-02-22
Abstract: La présente invention concerne un macrolide de stimulation immunitaire représenté par la formule (I). Le macrolide de l'invention trouve une utilité dans le traitement d'infections bactériennes intracellulaires, d'infections fongiques ainsi que des infections dues à des protozoaires.
Patent CA-3054880-A1 (CA)
Inventor: WHEBE SPIRIDON MICHEL
IPC: H02K1/28
Filed: 2017-03-03
Abstract: A salient pole machine (30) comprises a rotor (20) rotating about a machine axis, said rotor (20) having at its circumference a rotor rim (21 ) with a predetermined outer radius (29), whereby a plurality of salient poles (22), each extending in radial direction, is attached to said rotor (20) at said rotor rim (21 ) at a respective pole-rim interface (24). The mechanical properties of the configuration are improved by providing at said pole-rim interface (24) a plurality of axial rib-like rim extensions (25) projecting radially from said rotor rim (28) with a predetermined circumferential distance (d) between neighboring rim extensions (25), by each salient pole (22) having a plurality of axial pole grooves (26) matching and receiving said rib-like rim extensions (25) at the respective pole-rim interface (24), and by providing fixing elements (27) to fix said rib-like rim extensions (25) in said pole grooves (26).
Patent CA-3056003-A1 (CA)
Title: Ensemble embout buccal et dispositif de chauffage pour un dispositif d'inhalation
Inventor: CANE MICHAEL
IPC: A24F40/46
Filed: 2018-03-14
Abstract: L'invention concerne un ensemble pour un dispositif d'inhalation comprenant un embout buccal (623) et un dispositif de chauffage (10,100, 500,703). Le dispositif de chauffage comprend un substrat (12, 112, 212,512) qui supporte - au moins une partie d'élément résistif (14,114, 214, 514,705) appliquée sur une première région d'au moins une surface dudit substrat, - au moins une paire de contacts (113,213, 513) connectés chacun à l'au moins une partie d'élément résistif au niveau d'une extrémité desdits contacts et appliqués sur une seconde région dudit substrat, - une certaine quantité d'une composition (18) pouvant être transformée en aérosol déposée sur le substrat, le dispositif de chauffage étant disposé sensiblement dans l'embout buccal, au moins des parties de contacts étant tous les deux exposés et accessibles, et la surface de substrat sur laquelle la composition pouvant être transformée en aérosol a été déposée dans ou adjacente audit moyen de communication fluidique de telle manière que l'aérosol généré soit entraîné dans l'écoulement fluidique traversant ainsi ledit moyen de communication fluidique.
Patent CA-3057170-A1 (CA)
Inventor: FIETZ MELISSA
IPC: A47C1/00
Filed: 2019-10-01
Abstract: Il est décrit une chaire servant à supporter une personne allaitant un bébé. La chaise comprend un siège. La chaise comprend également un accoudoir attaché de manière fonctionnelle au siège. Laccoudoir peut tourner de manière sélective autour dun axe vertical et effectuer un déplacement sagittal, transversal ou frontal par rapport au siège. La forme de laccoudoir permet dy poser un bébé.
Patent CA-3057356-A1 (CA)
Inventor: NIZAMI SAFI
IPC: F01D21/06
Filed: 2019-10-01
Abstract: A method and system for operating a gas turbine engine coupled to an aircraft propeller are described herein. The method comprises detecting a command for unfeathering the propeller, inhibiting shaft shear detection logic in response to detecting the command for unfeathering the propeller, detecting completion of the unfeathering of the propeller, and enabling the shaft shear detection logic in response to detecting the completion of the propeller unfeathering.
Patent CA-3058431-A1 (CA)
Inventor: CHANDLER MICHAEL ADAM
IPC: A01H5/10
Filed: 2019-10-10
Abstract: ABRÉGÉ Une nouvelle variété de maïs désignée X03M275 ainsi que sa semence, ses plants et ses parties de plant sont produits par croisement de variétés de maïs autogames. Des méthodes de production dun plant de maïs comportent le croisement de la variété de maïs X03M275 avec un autre plant de maïs. Des procédés sont décrits pour produire un plant de maïs qui renferme dans son matériel génétique au moins un des traits introgressés dans la X03M275 par rétrocroisement ou transformation génétique, et les semences, plants et parties de plant du maïs produits de ce fait. La variété de maïs X03M275, les semences, les plants produits à partir des semences et les variantes, les mutations et les légères modifications de la variété de maïs X03M275 sont divulgués. Des procédés de production de variétés de maïs dérivées de la variété X03M275 et des méthodes dutilisation de la variété X03M275 sont aussi décrits. CA 3058431 2019-10-10
Patent CA-3063172-A1 (CA)
Inventor: MELMAN ARNOLD
IPC: C07K14/705
Filed: 2018-05-14
Abstract: La présente invention concerne des méthodes permettant d'atténuer un ou plusieurs signes ou symptômes de maladies des muscles lisses. Les compositions de l'invention peuvent comprendre un vecteur plasmidique contenant un acide nucléique qui code pour un peptide du canal Maxi-K. Les compositions de l'invention peuvent être administrées dans le détrusor au niveau d'au moins deux sites ou plus, en utilisant une seule dose unitaire.
Patent CA-3067177-A1 (CA)
Title: Sparse map for autonomous vehicle navigation
Inventor: SHASHUA AMNON
IPC: G08G1/0968
Filed: 2016-02-10
Abstract: Systems and methods are provided for constructing, using, and updating the sparse map for autonomous vehicle navigation. In one implementation, a non-transitory computer-readable medium includes a sparse map for autonomous vehicle navigation along a road segment.  The sparse map includes a polynomial representation of a target trajectory for the autonomous vehicle along the road segment and a plurality of predetermined landmarks associated with the road segment, wherein the plurality of predetermined landmarks are spaced apart by at least 50 meters.  The sparse map has a data density of no more than l megabyte per kilometer.
Patent CA-3068427-A1 (CA)
Inventor: MOY CHRISTINE
IPC: G06F21/00
Filed: 2018-06-27
Abstract: System and method for using a distributed ledger gateway are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for interacting with a plurality of distributed ledgers may include (1) receiving a client request comprising a payload to be written to one of a plurality of distributed ledgers and metadata extracted from the client request, (2) identifying a destination distributed ledger of the plurality of distributed ledgers, (3) logging a source of the request and the destination distributed ledger, (4) encrypting the payload, and (5) routing the encrypted payload to the destination distributed ledger
Patent CA-3068845-A1 (CA)
Title: A method to detect brain functional activities using hyperpolarized 129xe mr
Inventor: ALBERT MITCHELL
IPC: G01R33/485
Filed: 2020-01-20
Abstract: Described herein is a method for detecting changes in blood flow in a tissue portion and/or body portion of an individual. The method can be used to detect any sort of pathology, trauma or insult which results in blood flow change. Specifically, this method uses hyperpolarized 129Xe MRI to detect xenon perfusion changes in tissues such as brain tissue that corresponds to changes in blood flow, for example, changes caused by functional activities of the brain or regions of the body where blood flow may be compromised.
Patent CA-3077352-A1 (CA)
Inventor: NIAZI KAYVAN
IPC: C12N5/0783
Filed: 2018-10-04
Abstract: L'invention concerne des compositions, des procédés et des utilisations de cellules NK génétiquement modifiées pour déclencher une réponse immunitaire contre des cellules infectées par des micro-organismes. Dans certains modes de réalisation, les cellules NK peuvent être génétiquement modifiées à l'aide d'un acide nucléique recombiné qui comprend un segment codant pour un fragment d'un variant à chaîne unique extracellulaire qui se lie spécifiquement à un complexe antigène lipidique-CD1, un autre segment codant pour un domaine d'activation intracellulaire et une séquence de liaison entre ces segments. Dans d'autres modes de réalisation, les cellules NK peuvent être génétiquement modifiées à l'aide d'un acide nucléique recombiné qui comprend un segment codant pour un récepteur des lymphocytes T à chaîne a et un récepteur des lymphocytes T à chaîne ß, et un autre segment codant pour au moins une partie de CD3d et au moins une partie de CD3?. Les cellules NK génétiquement modifiées peuvent être administrées au patient infecté par un micro-organisme pour déclencher une réponse immunitaire spécifique aux cellules infectées par le micro-organisme.
Patent CA-3077892-A1 (CA)
Title: Prepolymer of elastomer material for screw drilling tool and preparation method thereof
Inventor: GUO DINGYU
IPC: E21B10/44
Filed: 2019-04-15
Abstract: The invention provides a prepolymer of elastomer material for screw drilling tools and a preparation method thereof. The prepolymer includes component A and component B, wherein the component A includes hydroxyl-terminated liquid rubber, polytetrahydrofuran diol, and polyether polyol; the component B includes at least one of an isocyanate, a cyanate, and a cyano compound; the mass ratio of the hydroxyl-terminated liquid rubber, polytetrahydrofuran diol, and polyether polyol is (0.2-1.0):(0.2-1.0):(0.2-1.0). The present invention introduces different molecular segments of different proportions through structural design, such that the molecular structure of the prepolymer has both rigid and flexible segments, thus to achieve an adjustable and controllable structure of the prepolymer; and the introduction of active groups makes the prepolymer to show good reactivity and processability. According to the present invention, a reactive elastomer material having excellent properties such as hardness, tear strength, and tensile strength can be obtained, and can be used as an elastomer material for screw drilling tools in the field of drilling technology.
Patent CA-3077995-A1 (CA)
Title: Watercraft that harvest both locomotive thrust and electrical power from wave motion
Inventor: HINE ROGER G
IPC: B63B1/30
Filed: 2012-06-28
Abstract: A wave-powered vessel, including: (a) a buoyant vessel body; (b) a mechanical means for converting movement of the vessel body caused by wave motion to horizontal thrust; and (c) a mechanical means including an electrical generator for converting movement of the vessel body caused by wave motion to electrical power, and including a piston powered by a swing arm that moves from a horizontal to a vertical position in accordance with the vertical movement of the vessel body.
Patent CA-3078293-A1 (CA)
Title: Method for producing a shoe with an air pump device, comprising a bellows which is formed in a midsole
Inventor: MOHLMANN WILHELM
IPC: B29D35/14
Filed: 2018-09-03
Abstract: The invention relates to a method for producing a shoe with an air pump device bellows which is arranged in the heel region, wherein an upper (2), a midsole (3), and an outsole (4) are first provided. The lower face (32) of the midsole (3) has a recess (36) for forming a cavity for the bellows and a surface which surrounds the recess on all sides and which comprises a surface profile, and the upper face (41) of the outsole (4) has a surface with a surface profile which complements the surface profile of the lower face of the midsole. The horizontal extension of the upper face (41) of the outsole (4) and of a sole section (22) of the upper (2) is greater than the horizontal extension of the midsole (3) such that the outsole (4) and the upper (2) protrude beyond the centered midsole (3) on all sides. In order to connect the upper (2), the midsole (3), and the outsole (4), the midsole (3) is first adhered onto the sole section (22) in a centered manner, and the upper (2) together with the midsole (3) are pressed onto the outsole (4) which is provided in the base element (6) of an injection mold. In the process, the complementary surfaces are adhered such that the cavity of the recess (36) is completely enclosed. The upper (2), the midsole (3), and the outsole (4) are then enclosed by an injection mold, and the outsole (4) upper face (41) surface regions which are not covered by the midsole (3), the outer surfaces of the midsole (3), and the lower face and adjacent lateral surface regions of the upper (2) are overmolded with an edge sole region plastic.
Patent CA-3079995-A1 (CA)
Title: Speed simulation effect
Inventor: BLUHM RICHARD DELOS
IPC: A63G31/16
Filed: 2018-11-05
Abstract: Provided herein is a ride system. The ride system includes a ride vehicle configured to move along a ride path at a first speed in a forward direction. Furthermore, the ride system includes a display system proximate the ride path, such that the display system displays imagery of an object moving at a second speed and away from the forward direction, and such that the second speed is based on a position of the ride vehicle, the first speed of the ride vehicle, or a combination thereof. The ride system also includes a control system that includes a processor and a memory device communicatively coupled to the processor. The memory devices stores instructions that cause the processor to provide a first control signal to cause the display system to change the second speed of the imagery based on the position of the ride vehicle, the first speed of the ride vehicle, or a combination thereof.
Patent CA-3082560-A1 (CA)
Title: Cellules immunoreactives secretant il-33 et leurs utilisations
Inventor: DANIYAN ANTHONY
IPC: C07K14/705
Filed: 2018-11-14
Abstract: La présente invention concerne des procédés et des compositions pour amplifier la réponse immunitaire à des cancers et des agents pathogènes. La présente invention concerne une cellule immunoréactive comprenant des récepteurs à reconnaissance d'antigène (par exemple, des récepteurs antigéniques chimériques (CAR) ou des récepteurs de lymphocyte T (TCR)), et exprimant un taux accru d'IL-33. Selon certains modes de réalisation de la présente invention, les cellules immunoréactives modifiées sont dirigées contre l'antigène et ont des propriétés d'activation immunitaire améliorées.
Patent CA-3085507-A1 (CA)
Title: A taro-based filled-dough product
Inventor: FIREBAUGH JON
IPC: A23L19/10
Filed: 2020-07-02
Abstract: A filled-dough product includes a filling and a dough wrapping enclosing the filling. The dough wrapping has a dough composition including taro and optionally a starch-rich tuber together on a dry basis in an amount from 4% to 6% by weight of the dough composition. The dough composition further includes tapioca starch in an amount from 15% to 25%  by weight of the dough composition, waxy maize starch in an amount from 25% to 35% by weight of the dough composition, pregelatinized hydroxypropyl distarch phosphate in an amount from 1% to 3% by weight of the dough composition, and water in an amount of up to 55% by weight of the dough composition.
Patent CA-3085560-A1 (CA)
Inventor: DILLING GARY
IPC: B25B23/00
Filed: 2018-11-30
Abstract: Various embodiments described herein provide a fastener system having straight walled driving surfaces that provides a reliable stick fit feature, while also improving stability of engagement between the system components. A feature of the new system is to allow stick fit engagement of existing standard straight walled drivers in the new system.
Patent CA-3085717-A1 (CA)
Inventor: VAINSENCHER AMIT
IPC: G06N3/08
Filed: 2017-12-14
Abstract: Procédé consistant à amener une pluralité de procédures d'étalonnage de bits quantiques à être effectuées sur un ou plusieurs bits quantiques conformément à un processus d'étalonnage automatique de bits quantiques. Des données de journal sont stockées, comprenant au moins : un enregistrement identifiant une ou plusieurs procédures d'étalonnage qui ont été effectuées, et des informations concernant le résultat des procédures d'étalonnage respectives. Des données d'entraînement sont sélectionnées parmi les données de journal et sont reçues au niveau d'un module d'apprentissage fonctionnant au niveau d'un ou de plusieurs dispositifs informatiques. Un modèle d'apprentissage supervisé est entraîné au niveau du module d'apprentissage pour sélectionner des paramètres de bits quantiques à étalonner et/ou à vérifier.
Patent CA-3087490-A1 (CA)
Inventor: HUBERT CASEY
IPC: E21B43/22
Filed: 2016-09-22
Abstract: Un procédé et un système sont décrits pour récupérer l'huile d'unités géologiques contenant de l'huile actuellement inaccessible par activation d'une banque de semences microbiennes de la biosphère profonde. Les nutriments et l'amélioration thermique de micro-organismes dans des unités géologiques contenant de l'huile permettent de stimuler des micro-organismes dormants et/ou inactifs, de sorte qu'ils prolifèrent et produisent du gaz. La viscosité de l'huile qui est diminuée par la chaleur, ainsi que la pression de gaz produite par des microbes activés permettent à de l'huile précédemment inaccessible de s'écouler vers des puits de production.
Patent CA-3087776-A1 (CA)
Title: Particulate laundry softening wash additive
Inventor: PANANDIKER RAJAN KESHAV
IPC: C11D3/37
Filed: 2019-01-29
Abstract: Disclosed are compositions comprising a plurality of particles, said plurality of particles comprising: 25% to 94% by weight of a water-soluble carrier; and 5% to 45% by weight of a branched polyester polymer, wherein said branched polyester polymer is (see above formula) wherein: each A is independently a branched hydrocarbon chain comprising 4 to 100 carbon atoms;  Q is selected from an alkyl chain comprising 1 to 30 carbon atoms and a hydrogen atom; T is a hydrogen atom or a ¨C(O)-R wherein each R is an alkyl chain comprising 1 to 30 carbon atoms;  and n is an integer from 1 to 100; and optionally a deposition aid;wherein each of said particles has a mass from 1 mg to 1 g; and wherein said particles have an onset of melt from 25 °C to 120°C.  Also disclosed are methods of softening a fabric involving the use of the compositions herein defined.
Patent CA-3090972-A1 (CA)
Inventor: DELLA VALLE FRANCESCO
IPC: A23L33/125
Filed: 2020-08-24
Abstract: The present invention relates to a composition based on N-palmitoyl-ethanolamide and Rutin in co-micronized form. In particular, the present invention relates to a composition comprising a mixture of palmitoyl-ethanolamide (PEA) and Rutin in co-micronized form in which the PEA/Rutin ratio is between 10:1 and 1:1.  Pharmaceutical formulations for the treatment of humans and animals also form an object of the invention. The composition of the invention is useable for the treatment of diseases of arteries and arterioles.
Patent CA-3091080-A1 (CA)
Inventor: MATHUIS PHILIP
IPC: G01N33/50
Filed: 2019-03-15
Abstract: A method for providing a viral infection status of at least one cell in a cell sample comprising receiving holographic information (304) of the cell sample obtained by digital holographic microscopy, and determining from the holographic information, the viral infection status (306) of the at least one cell.
Patent CA-3092936-A1 (CA)
Inventor: BESSAC LAURENCE
IPC: A61K39/395
Filed: 2019-03-06
Abstract: The present invention provides methods for treating diseases and disorders that are associated with elevated levels of lipids and lipoproteins. The methods of the present invention comprise administering to a high cardiovascular risk patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P or alirocumab. The methods of the present invention are useful for treating high cardiovascular risk patients with hypercholesterolemia and elevated levels of other atherogenic lipoproteins that are not adequately controlled by maximum tolerated dose statin therapy. In particular, the methods of the present invention are useful for reducing cardiovascular risk and lowering atherogenic lipoproteins in high cardiovascular risk patients within 12 months following an acute coronary syndrome event despite a maximum tolerated dose statin therapy.
Patent CA-3098779-A1 (CA)
Inventor: ARMBRUSTER FRANZ PAUL
IPC: G01N21/64
Filed: 2019-05-07
Abstract: An analyte testing system for quantifying the presence of an analyte in a speciment by lateral flow chromatography. The system comprises a test cassette (10) with a lateral flow chromatography and a mobile hand-held processor device (16) comprising a digital camera (16a), a source of light (16b) and a processor (16c), which software and hardware (16c) are configured to determine automatically the distance between camera and object and the measures of light in the region of interest of the lateral flow chromatography prior any retrieval of image data for further analysis and quantification of the visual signals.
Patent CA-3100092-A1 (CA)
Title: Anti-human interleukin 17a monoclonal antibody and application thereof
Inventor: QIU JIWAN
IPC: A61P37/00
Filed: 2018-05-17
Abstract: Disclosed by the present invention are an anti-human interleukin 17A monoclonal antibody and an application thereof. The human interleukin 17A epitope that binds to the monoclonal antibody comprises 78th asparagine (N78). The antibody may be used to treat rheumatoid arthritis, psoriasis, multiple sclerosis, psoriatic arthritis, plaque psoriasis and/or ankylosing spondylitis.
Patent CA-3100815-A1 (CA)
Title: Methods and systems for automatic radiotherapy treatment planning
Inventor: ZAREPISHEH MASOUD
IPC: A61N5/06
Filed: 2019-03-07
Abstract: Systems and methods for improved radiation treatment planning can employ hierarchical constrained optimization with relaxed constraints also referred to herein after as expedited hierarchical constrained optimization (ECHO). The systems and methods described herein employ a combination of constrained optimization and a correction loop involving unconstrained optimization to enhance the speed and efficiency of the radiation treatment planning process and improve the accuracy and quality of resulting radiation treatment plans. The use of a hierarchical constrained optimization approach leads to less complex and faster to solve optimization problems. The correction loop allows for compensating for optimization error associated with the sequence of constrained optimizations by incorporating such error in an unconstrained optimization. Hard and soft dose volume constraints can be efficiently incorporated.
Patent CA-3101943-A1 (CA)
Title: Therapeutic methods using antibody drug conjugates (adcs)
Inventor: BOITANO ANTHONY
IPC: A61K47/68
Filed: 2019-06-07
Abstract: The invention relates to dosing regimens for antibody drug conjugates, as well as methods of administering said dosing regimens to patients suffering from or at risk of various diseases and conditions such as autoimmune diseases, cancers, and Graft versus Host Disease (GvHD), among others, by administration of an antibody drug conjugate (ADC), capable of binding an antigen expressed by a hematopoietic cell, such as a hematopoietic stem cell, an immune cell or a cancer cell.
Patent CA-3103500-A1 (CA)
Inventor: KONG JIXIANG
IPC: A01H4/00
Filed: 2019-06-14
Abstract: This document relates to methods and materials for genome engineering in eukaryotic cells, and particularly to methods for increasing genome engineering (i.e. transformation or genome editing) efficiency via co-delivery of combinations of one or more booster polypeptides, and boost genes, with genome engineering components.