baber/WOPTO huggingface dataset:
Patent NZ-277698-A (NZ)
Title: Dust mite allergens, recombinant production
Inventor: THOMAS WAYNE R
IPC: A61P37/08
Filed: 1994-12-07
Abstract: Isolated nucleic acids encoding an allergen of Dermatophagoides pteronyssinus, Der p III, are disclosed. A cDNA encoding a peptide having a Der p III activity and a predicted molecular weight of about 24,985 daltons is also described. The nucleic acids can be used as probes to detect the presence of Der p III nucleic acid in a sample or for the recombinant production of peptides having an activity of Der p III. Peptides having an activity of Der p III can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mites.
Patent NZ-289954-A (NZ)
Title: Medicament comprising local anaesthetic agents, polar lipids and triacylglycerol; used to relieve pain
Inventor: BRODIN ARNE FOLKE
IPC: A61K31/245
Filed: 1995-06-21
Abstract: PCT No. PCT/SE95/00760 Sec. 371 Date Sep. 18, 1995 Sec. 102(e) Date Sep. 18, 1995 PCT Filed Jun. 21, 1995 PCT Pub. No. WO96/01637 PCT Pub. Date Jan. 25, 1996A new pharmaceutical preparation comprising one or more local anaesthetic agents, a polar lipid, a triacylglycerol and optionally water. The new pharmaceutical preparation is excellent for topical treatment of pain.
Patent NZ-311108-A (NZ)
Title: Bolt unit for lock, bolt passes through keeper on door frame to engage receptor that moves with bolt housing
Inventor: KIBBLE ANTHONY WILFRED
IPC: E05B65/48
Filed: 1996-06-26
Abstract: A lock unit for a door 36 includes a housing 10 containing a slidable bolt 12.  The bolt, when in the locked position, passes through a keeper 22 attached to the door frame 38, and then passes into a receptor 50 which is attached to and which moves with housing 10.  This arrangement is intended to prevent the lock being burst open by a force perpendicular to the plane of the door.
Patent NZ-315601-A (NZ)
Title: Gas phase polymerisation of olefins in which growing polymer particles are recycled under gravity from a first zone through a second zone and back to the first zone
Inventor: GOVONI GABRIELE
IPC: C08F110/06
Filed: 1996-07-17
Abstract: Process for gas-phase polymerization carried out in two interconnected polymerization zones, to which one or more alpha-olefins CH2=CHR are fed in the presence of catalyst under reaction conditions and from which the polymer product is discharged. The process is characterized in that the growing polymer flows through a first polymerization zone under fast fluidization conditions, leaves said first zone and enters a second polymerization zone through which it flows in a densified form under the action of gravity, leaves said second zone and is reintroduced into the first polymerization zone, thus establishing a circulation of polymer around the two polymerization zones. The novel process allows olefins to be polymerized in the gas phase with high productivity per unit volume of the reactor without incurring the problems of the fluidized-bed technologies of the known state of the art.
Patent NZ-325307-A (NZ)
Title: Nitric oxide (no) synthase inhibitor to prevent type II diabetes
Inventor: TURNER NICHOLAS CHARLES
IPC: A61K31/195
Filed: 1996-12-18
Abstract: A method for the prophylactic treatment of Type II diabetes, which method comprises the administration, to a human or non-human mammal, of an effective non-toxic pharmaceutically acceptable amount of a NO synthase inhibitor, such as aminoguanidine, or a pharmaceutically acceptable derivative thereof.
Patent NZ-330926-A (NZ)
Title: Expression augmenting sequence elements (ease) for eukaryotic expression systems
Inventor: MORRIS ARVIA E
IPC: C12N15/11
Filed: 1997-01-10
Abstract: There are disclosed nucleotide sequences which can improve expression of recombinant proteins two to eight fold in stable cell pools when present in an expression vector.
Patent NZ-331283-A (NZ)
Title: Low ph germicidal iodine compositions having enhanced stability
Inventor: MCKINZIE MICHAEL D
IPC: A61P31/04
Filed: 1997-02-07
Abstract: Stable aqueous iodine/iodide/iodate germicidal compositions are provided which have relatively high quantities of free iodine therein and also substantially maintain the starting amounts of available and free iodine throughout a storage period of at least about three months. The compositions of the invention contain from about 0.01-1.4% by weight available iodine, from about 10-125 ppm free iodine, from about 0.005-0.5% by weight iodate ion, from about 0.1-15% by weight of iodine complexing agent, from about 0.004-0.5% by weight iodide ion, and have a pH of from about 2.0-4.5.
Patent NZ-331580-A (NZ)
Title: Recombinant phages
Inventor: MARDH SVEN
IPC: A61K31/00
Filed: 1997-02-05
Abstract: The present invention relates to bacteriophages for use in the treatment or prophylaxis of bacterial infections, especially mucosal bacterial infections such as Helicobacter pylori infections. In particular, it relates to modified filamentous bacteriophages, e.g. M13 phages, for such use, which bacteriophages present at its surface a recombinant protein comprising: (i) a first component derived from a bacteriophage surface protein; and (ii) a second component comprising variable region sequences of an antibody to provide a bacterial antigen binding site, said second component rendering said bacteriophage capable of binding to and thereby inhibiting growth of bacterial cells involved in the etiology of said infection.
Patent NZ-331821-A (NZ)
Title: Solid pharmaceutical composition comprising a retinoid and polyethylene glycol
Inventor: SHERMAN BERNARD CHARLES
IPC: A61K31/07
Filed: 1998-09-10
Abstract: Compositions of solid solutions of retinoid in polyethylene glycol are disclosed.  Such compositions are said to improve the rate and extent of absorption of retinoid compared to that of pure crystalline retinoid.
Patent NZ-334745-A (NZ)
Title: Metal deficient perovskite-like ceramic material for use in the separation of oxygen from gas mixture
Inventor: GORDES PETRU
IPC: C04B35/50
Filed: 1999-03-19
Abstract: A perovskite ceramic material having the formulas AxA'x'A''x''A'''x'''ByB'y'B''y''B'''y'''O3-d, wherein A, A' & A'' each are one or more metal selected from the lanthanide group; A''' is at least one alkali earth metal; B, B' & B'' each is a metal selected from the group of transition metals, group 3a and noble metals of group 8; B''' is at least one metal selected from the groups 2a, 3b, 4b, 5b, 6b, 7b, 8, 1b, 2b, 3a & 4a; Sxi = x + x' + x'' + x''' < 1 and Syi = y + y' + y'' + y''' [ 1 or Sxi = x + x' +x'' + x''' [ 1 and Syi = y + y' + y'' + y''' < 1, such that Sxi ¹  Syi  and -1 < d < 1
Patent NZ-337907-A (NZ)
Title: Hydraulic circuit for stabilising the lower links of a tractor three-point linkage
Inventor: ADAMEK DIPL-ING WOLFGANG
IPC: B62D49/00
Filed: 1999-09-20
Abstract: A hydraulic circuit is used to stabilise the lower links 1 of a tractor three-point linkage.  The links are stabilised by single acting hydraulic cylinders 7.  The links 1 are lifted by the action of hydraulic cylinder 10 acting on lifting arms 11.  When the line 14 leading to cylinder 10 is pressurised, fluid is also fed via valve 23 to the cylinders 7, which has the effect of centring the links.  A non-return valve 20 is provided in the line 14, the valve opening at a pressure of ³ 10 bar.  A bypass line 21 with a non-return valve 20 allows fluid to return from cylinder 10.
Patent NZ-504631-A (NZ)
Title: Gastro-intestinal sustained release bolus delivery system containing Duddingtonia flagrans
Inventor: MUNDAY REX
IPC: A61K9/00
Filed: 2000-05-18
Abstract: A delivery mechanism for the introduction of a biological agent to an animal characterised in that the delivery mechanism is a bolus which contains a biological agent. In the preferred embodiments, the biological agent is Duddingtonia flagrans and the animal to which the mechanism is introduced is a sheep.
Patent NZ-505142-A (NZ)
Title: Benzylidene pyrazolones useful as herbicides
Inventor: RHEINHEIMER JOACHIM
IPC: C07D409/10
Filed: 1998-11-06
Abstract: A benzylidenepyrazolone of the formula I which may  be in  cis  or  trans  form or a mixture thereof  useful  as  a herbicide wherein: R1 is alkyl or haloalkyl; R2  is  alkyl, haloalkyl, alkoxy, haloalkoxy, halogen, nitro or cyano; R3   is  hydrogen,  halogen,  nitro,  cyano,  NR5R6,  OCOR5, NR5COR6,    CO2R5,   -COSR5,   -CONR5R6,   alkoxyiminoalkyl, alkylcarbonyl  or  optionally  substituted  alkyl,   alkoxy, alkylthio, alkenyl, alkynyl, phenyl, phenoxy or an 5- or  6- membered optionally saturated heterocycle which may  contain up  to  4  nitrogen atoms and/or up to 2 oxygen  or  sulphur atoms as ring members; R4 is alkyl or haloalkyl or R3   and  R4  form  an  optionally  substituted,  optionally saturated  2-  or  3-membered bridge, which  may  contain  a sulphur  atom,  which may be oxidized to give sulphoxide  or sulphone; R5 is hydrogen or optionally substituted alkyl; R5 is optionally substituted alkyl; R7 is hydrogen, alkyl or haloalkyl; n is 0, 1 or 2 and X is hydrogen, chlorine or bromine. The benzylidenepyrazolone defined above can be prepared from a benzoylpyrazolone of the formula (II).
Patent NZ-505542-A (NZ)
Title: Stack indexable container made from a blank
Inventor: COE ROBERT WILLIAM
IPC: B65D13/00
Filed: 2000-06-30
Abstract: A  stack indexable container formed from  a  container body  blank and a pair of end panels (10).  The blank has  a rectangular base (1), a sequence of flaps from each  of  the longer  sides  of the base (1), a first flap  of  each  flap sequence forming at least part of each side wall (6) of  the container  body,  with at least one further  flap  therefrom providing  part of a lid (8), and a flap from  each  of  the shorter sides of the base (1) providing an end wall  (3)  of the  container  body.  Each end wall flap has  an  extension (5)  at each end.  In the erected container, each end  panel is  fixed  inwardly  of its associated  end  wall  flap  and extends  substantially from one sidewall to the  other,  and each  extension (5) is attached to a side wall  flap.   Each end   panel  presents  a  plurality  of  upwardly   directed indexing projections (11) indexable into the base of a  like erected  container  having  appropriate  openings   (2)   or cutaways formed therein.
Patent NZ-505809-A (NZ)
Title: (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol and its salts and pharmaceuticals thereof; useful as medicaments
Inventor: MORGAN PHILLIP FREDERICK
IPC: C07D265/32
Filed: 1999-01-20
Abstract: Pharmaceutical compositions comprising (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol or a pharmaceutically acceptable salt or solvate thereof together with one or more pharmaceutically acceptable carriers, diluents, or excipients. Also described is the compound (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol or a pharmaceutically acceptable salt or solvate thereof for use in therapy. The compound (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol or a pharmaceutically acceptable salt or solvate thereof is useful for the treatment of depression, attention deficit hyperactivity disorder, obesity, migraine, pain, sexual dysfunction, Parkinson's disease, Alzheimer's disease, addiction to cocaine or nicotine-containing products
Patent NZ-509522-A (NZ)
Title: Surface coatings
Inventor: BADYAL JAS PAL SINGH
IPC: B05D7/00
Filed: 1999-07-02
Abstract: Described is a method of coating a surface with a polymer layer.  The method comprising exposing the surface to a pulsed plasma comprising a monomeric saturated organic compound, wherein the length of the pulse is not constant throughout the deposition process.  The organic compound comprising an alkyl chain of at least 5 carbon atoms, wherein the alkyl chain is substituted by halogen and optionally interposed with a heteroatom. The method produces an oil or water repellant coating on a surface.
Patent NZ-514872-A (NZ)
Title: Truncated VEGF-B, VRF-2, VEGF-C, PlGF, VEGF-3, poxvirus ORF-1 and poxvirus ORF-2 proteins
Inventor: BOHLEN PETER
IPC: A61P9/00
Filed: 1998-04-20
Abstract: A use of a truncated VRP subunit having a deletion of at least one of the amino acid residues N-terminal to the first cysteine of the core sequence of said subunit, in the manufacture of a medicament for stimulating blood vessel formation in a patient in need thereof with the proviso that said truncated VRP is not a truncated VEGF-3 subunit. (62) Divided out of 500530
Patent NZ-516665-A (NZ)
Title: Device for enhancing removal of liquid from fabric
Inventor: HAYNIE DAN
IPC: F26B5/12
Filed: 2000-07-18
Abstract: A device for enhancing removal of liquid from fabric, such as a vacuum head device (10) for removing liquid from carpet (not shown), includes an elongated base plate (18) to be moved across the carpet. The vacuum head (10) had a tapering cross section with a wider upper end and a narrower lower end configured to penetrate into the carpeted surface (not shown). In addition, a plurality of apertures (22) are formed in an array in the base plate (18) to withdraw the fluid under a vacuum force. Preferably, the plurality of apertures (22) are sized larger than a width of the lower surface to create a plurality of protrusions (38) extending from the base plate (18) configured to penetrate the carpeted surface (14).
Patent NZ-516825-A (NZ)
Title: Aminobenzophenones as inhibitors of IL-1beta and TNF-alpha
Inventor: OTTOSEN ERIK RYTTER
IPC: A61P17/02
Filed: 2000-07-11
Abstract: A compound of formula I, where: - R1 represents one or more, same or different substituents selected from halogen, hydroxy, mercpato, trifluoromethyl, amino, (C1-C3)alkyl, (C2-C3)olefinic group, (C1-C3)alkoxy, (C1-C3)alkylthio, (C1-C6)alkylamino, (C1-C3alkoxycarbonyl, cyano, carbamoyl, nitro and phenyl; - R2 represents one substituent in the ortho position being selected from halogen, hydroxy, mercapto, trufluoromethyl, amino, (C1-C3)alkyl, (C2-C3)alkoxycarbonyl, cyano, carbamoyl, nitro and phenyl; - R3 represents one or more, same or different substituents selected from the group consisting of hydrogen, halogen, hydroxy, mercapto, trifluoromethyl, amino, (C1-C3)alkyl, (C2-C3)olefinic group, (C1-C3)alkoxy, (C1-C3)alkylthio, (C1-C6)alkylamino, (C1-C6)alkylmino, (c1-C3)alkoxycarbonyl, cyano, carbamoyl, phenyl and carboxy; - R4 represents hydrogen, (C1-C3)alkyl or allyl; - Q represents a bond, or C(R6)(R7)(-O-C=O)-, in which R6 and R7 independently represents hydrogen, trifluoromethyl, or (C1-C4)alkyl; - Y represents either (C5-C15)alkyl, (C2-C15)alkyl, (C2-C15)olefinic group, (C3-C10)monocyclic hydrocarbon, or phenyl, any of which may be optionally substituted with one or more, same or different substitutents represented by the formula R5; or (C1-C4)alkyl substituted with at least one or more substituents with the formula R5; - R5 represents halogen, hydroxy, mercapto, trifluoromethyl, amino, (C1-C3)alkoxy, (C1-C3)alkylthio, (C1-6)alkylamino, (C1-3)alkoxycarbonyl, cyano, azido, nitro, -COOH, -CONH2, CONHR', or CONR'R', where R' represents (C1-3)alkyl; and - X represents oxygen or sulphur. A compound formula I as described may be used in treatingastham, allergy, arthritis, gout, atherosclerosis, chronic inflammatory bowel disease, proliferative and inflammatory skin disorders, uvetis, septic shock, AIDS or osteoporosis. A compound of formula I may be used in combination with other drugs such as: Glucocorticosteroids, vitamin D analogues, anti-histamines, PAF antagonists, certain NSAIDs, gold slats, retinoids, cholesterol lowering agents, zinc salts, salazopyrin, methyl xanthines.
Patent NZ-517002-A (NZ)
Title: Multipotent adult stem cells and methods for isolation
Inventor: FURCHT LEO T
IPC: A61K39/00
Filed: 2000-08-04
Abstract: An isolated cell, which is not an embryonic stem cell, embryonic germ cell or germ cell, which is positive for oct 3/4 and can be maintained in culture in the undifferentiated state or differentiated into at least one cell type of each of the endodermal, ectodermal and mesodermal embryonic lineages. Also provided are methods of isolation and culture, as well as therapeutic uses for the isolated cells.
Patent NZ-521852-A (NZ)
Title: Novel processes for preparing torsemide intermediate
Inventor: KORDOVA MARCO
IPC: A61K31/44
Filed: 2001-03-20
Abstract: A process for preparing a compound of formula (I), in particular (3-sulfonamide-4-chloro)pyridine, comprising the steps of: (a) adding a compound of formula (II) to an organic solvent to form a mixture, (b) adding ammonia to the mixture of step (a), and (c) isolating the compound of formula (I), wherein X1 and X2 are each independently chloro, fluoro or bromo, from the mixture of step (b).
Patent NZ-522301-A (NZ)
Title: Vaccine comprising a tick cement protein
Inventor: TRIMNELL ADAMA ROSEANNE
IPC: A61P33/14
Filed: 2001-04-25
Abstract: A vaccine composition comprising an immunogenic fragment of a tick cement or a functional equivalent thereof in conjunction with a pharmaceutically acceptable excipient. The fragment of functional equivalent contains an immunogenic epitope that is also present in a gut protein of a blood feeding ectoparasite.
Patent NZ-522766-A (NZ)
Title: Compositions and methods for the treatment of colorectal cancer with irinotecan and thalidomide to reduce side effects
Inventor: GOVINDARAJAN RANGASWAMY
IPC: A61K31/445
Filed: 2001-05-10
Abstract: Irinotecan and thalidomide can be used in synergistic amounts for the manufacture of a composition or kit for treating colon or rectal cancer, reducing a does limiting adverse effects associated with irinotecan, increasing the therapeutic efficacy of irinotecan and/or reducing or eliminating gastrointestinal toxicity associated with irinotecan.
Patent NZ-525981-A (NZ)
Title: Apparatus for dispensing a roll of material
Inventor: KELDERS JOHANNES H J M
IPC: B65H35/00
Filed: 2001-11-14
Abstract: A dispenser 10 for dispensing a roll of material 24 such as a pressure sensitive adhesive tape is disclosed. The apparatus includes an enclosable housing 12 having a roll holding piece 14, a cover piece 16, and a hinge assembly 22 for joining the roll holding piece and cover piece. The cover piece includes a depression for placement of a finger. The hinge assembly 22 permits opening of the housing while keeping the cover piece and roll holding piece connected. The dispenser 10 also includes an applicator 30 located at the dispensing end for applying pressure to the material 24 being dispensed, a discharge opening for the material, and a cutting member 28 located at the dispensing end for cutting the material. (see drawing on next page
Patent NZ-526005-A (NZ)
Title: Method and apparatus for flow cytometry
Inventor: MALACHOWSKI GEORGE C
IPC: G01N33/48
Filed: 2003-05-20
Abstract: A method for flow cytometer comprises establishing a stream with a flow cytometer, the stream having a droplet break off point where the stream breaks off into droplets and a free-fall zone where the droplets move after becoming droplets, ejecting the stream from the flow cytometer at a stream exit point, determining an approximate speed of the stream at a first position along the stream, determining an approximate speed of the stream at a second position along the stream, and modeling the speed of the stream as decaying approximately exponentially relative to distance in a region occurring between about the stream exit point and about the droplet break off point. (62) Divided out of 506352
Patent NZ-528102-A (NZ)
Title: Universal setting tool for adhesively bonded rebar and threaded rod anchors
Inventor: ERNST RICHARD J
IPC: B25B31/00
Filed: 2003-09-09
Abstract: A universal setting tool for use in connection with insertion and fixation of different anchors within bores performed within a substrate. The rebar or threaded rod anchor 158 is axially inserted into the open end of the large diameter bore 124 and axially fed through such large-diameter bore portion 124 until the upper end portion 160 of the rebar or threaded rod anchor 158 encounters the upper end portion of the tapered diameter section 136 of the coil spring member 132, or the lower end portion of the stacked-coil small diameter section 138 of the coil spring member 132 such that frictional contact is effectively established between the upper end portion 160 of the rebar or threaded rod anchor 158 and the coil spring member 132.
Patent NZ-530449-A (NZ)
Title: Composition comprising wenguanguo extracts, methods for preparing same and uses thereof
Inventor: WANG YUN
IPC: A23L33/00
Filed: 2002-08-28
Abstract: Disclosed is a Wenguanguo husk extract comprising at least 50% saponin by weight and the process of producing a combined extract involving extracting a powder comprising milled Wenguanguo husks with an ethanol to form an organic extract; removing the organic solvent from the extract; adding water to form an aqueous extract; and drying the aqueous extract, wherein the extract comprises at least 30% saponin by weight. The extracts can be used to make medicines or health foods for preventing cerebral aging, improving cerebral functions and curing enuresis, frequent micturition, urinary incontinence, dementia, weak intelligence and Alzheimer's disease, autism, brain trauma, Parkinson's disease other diseases caused by cerebral dysfunctions, and treating arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome. The extracts contain saponin, saccharides, proteins and others.
Patent NZ-530834-A (NZ)
Title: Near-critical extraction of totarol and/or a product containing totarol
Inventor: MENDE DOUGLAS ANTHONY
IPC: A61K8/97
Filed: 2004-01-28
Abstract: A process for producing a totarol-containing extract from Podocarpus, Dacrycarpus or Cupressus species is described, which comprises the steps of (a) contacting the plant material with a near-critical fluid to produce a near-critical fluid phase in which the totarol is dissolved, (b) separating the near-critical fluid phase from the plant material and (c) separating the totarol-containing extract from the near-critical fluid. An additional process is described which involves the co-extraction of totarol and an oil-containing material from a plant material. The totarol-containing extract has activity against both Gram-positive and Gram-negative bacteria and is suitable for incorporation in a therapeutic or cosmetic formulation.
Patent NZ-533413-A (NZ)
Title: HIV integrase inhibitors
Inventor: WALKER MICHAEL A
IPC: A61K31/335
Filed: 2002-12-06
Abstract: Disclosed is the inhibition of HIV integrase, and to the treatment of AIDS or ARC by administering compounds of the formula I, or a tautomer of said compound, or a pharmaceutically acceptable salt, or solvate thereof.
Patent NZ-535955-A (NZ)
Title: A rock bolt
Inventor: ALTOUNYAN PETER FRANK REINHOLD
IPC: E21D20/02
Filed: 2003-04-14
Abstract: A rock bolt (1) comprising an elongate body having torque limiting means at an outer end (3) of the body, the torque limiting means having at least one deformable protrusion (2) that deforms under a predetermined torque. There is provided for the deformation of the deformable protrusion (2) to prevent further rotation of the rock bolt (1) by a torque application apparatus. A further feature of the invention provides for the deformable protrusion (2) to be shaped to receive a complementary shaped chuck on a torque application apparatus to facilitate transferring torque to the rock bolt (1). Further features of the invention provide for the deformable protrusion to be protrusions extending in an axial direction from an end surface of the rock bolt (1).
Patent NZ-539715-A (NZ)
Title: Pharmaceutical tablets containing tibolone and a coating, which reduces the formation of the tibolone-derived isomerisation degradation product OM38
Inventor: DE HAAN PIETER
IPC: A61K9/28
Filed: 2003-11-13
Abstract: Disclosed is a stabilized pharmaceutical tablet comprising: an amount from 0.1 to 10% by weight of tibolone, with a coating which achieves a stabilizing effect with respect to the formation of Org OM38 upon storage. Said coating is preferably a sugar, sugar film or wrap coating.