baber/WOPTO huggingface dataset:
Patent CA-2677568-A1 (CA)
Title: A recombinant host cell for the production of a compound of interest
Inventor: WOSTEN HERMAN ABEL BERNARD
IPC: C12N1/14
Filed: 2008-02-12
Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The present invention also relates to isolated fungal promoter DNA sequences, to DNA constructs, vectors, and fungal host cells comprising these promoters in operative association with coding sequences encoding a compound of interest. The present invention also relates to methods for expressing a gene of interest and/or producing compounds of interest using a promoter according to the invention.
Patent CA-2678259-A1 (CA)
Inventor: PANICALI DENNIS
IPC: A61K39/00
Filed: 1999-11-12
Abstract: The present invention is a recombinant vector encoding and expressing at least three or more costimulatory molecules. The recombinant vector may additionally contain a gene encoding one or more target antigens or immunological epitope thereof. The synergistic effect of these costimulatory molecules on the enhanced activation of T cells is demonstrated. The degree of T-cell activation using recombinant vectors containing genes encoding three costimulatory molecules was far greater than the sum of recombinant vector constructs containing one costimulatory molecule and greater than the use of two costimulatory molecules. Results employing the triple costimulatory vectors were most dramatic under conditions of either low levels of first signal or low stimulator to T-cell ratios. This phenomenon was observed with both isolated CD4<+> and CD8<+> T cells. The recombinant vectors of the present invention are useful as immunogenes and vaccines against cancer and pathogenic micro-organisms, and in providing host cells, including dendritic cells and splenocytes with enhanced antigen-presenting functions.
Patent CA-2678548-A1 (CA)
Inventor: BURNHAM JEFFREY C
IPC: C05F7/00
Filed: 2008-02-19
Abstract: The invention describes a method for treating sludge to produce high nitrogen organically-augmented inorganic fertilizer that can compete with traditional The method involves conditioning dewatered biosolids or organic sludge, and treating with an oxidizer to reduce odorant effects and an acid This mix is then interacted with concentrated sulfuric and or phosphoric acids and an ammonia source or alternatively a hot or molten melt or salt of ammonium sulfate/phosphate to form a fertilizer mix under controlled temperature, pressure and retention times This invention can also be an add-on to commercial production of ammonium salts The fertilizer produced by the present invention contains more than 8 wt % nitrogen and preferably 15 wt % nitrogen The invention is tailored for biosolids production in individual municipal waste treatment plants by keeping the fertilizer manufacturing plants of the present invention small with a minimization of logistics and liability
Patent CA-2679224-A1 (CA)
Inventor: MOSS STEVEN
IPC: A61P35/00
Filed: 2008-03-03
Abstract: According to the invention there are provided derivatives of a C21-deoxy ansamycin or salt thereof which contain a 1-hydroxyphenyl moiety bearing at position 3 an aminocarboxy substituent, in which position 5 and the aminocarboxy substituent at position 3 are connected by an aliphatic chain of varying length characterised in that the 1-hydroxy position of the phenyl ring is derivatised by an aminoalkyleneaminocarbonyl group, which alkylene group (which may optionally be substituted by alkyl groups) has a chain length of 2 or 3 carbon atoms, a phosphoric acid, or a phosphoric acid ester (such as an alkyl ester) group, or a salt thereof, and which derivatising group increases the water solubility and/or the bioavailability of the parent molecule. Such compounds are useful in therapy eg in the treatment of cancer and B-cell malignancies.
Patent CA-2680238-A1 (CA)
Inventor: HIBI TORU
IPC: A61K31/40
Filed: 2008-07-16
Abstract: Organoleptically acceptable oral dosage formulations of an indole receptor serotonin agonist, and methods of making and using the same, are provided. An aspect of the formulations is that they include an indole receptor serotonin agonist and a masking component. In certain embodiments, the masking component includes one or more of an amino acid and an organic acid. The subject invention finds use in a variety of applications.
Patent CA-2682196-A1 (CA)
Title: Measurement of an insoluble analyte in a sample
Inventor: BOTROS IHAB
IPC: C12Q1/68
Filed: 2008-03-31
Abstract: The present invention relates to compositions, apparatus and methods useful for concurrently performing singular, multiple, high throughput, biological or chemical assays, using nuclease protection molecules which specifically bind to a target of interest. The nuclease protection molecules are capable of detecting targets in complex biological samples, including, preserved, fixed, dried, and/or cross-linked specimen. The reagents and methods of the instant invention provide an effective means for analyzing a target of interest from a complex biological sample without solubilizing or disrupting the sample. Utilization of such methods in clinical and/or diagnostic applications is also described.
Patent CA-2687545-A1 (CA)
Inventor: PIKALOV SERGEEVICH MIKHAIL
IPC: A61P1/00
Filed: 2008-02-27
Abstract: The invention relates to the chemical and pharmaceutic industry, in particular to an agent used for stimulating lymphatic drainage and comprising drinking water which was exposed to baromembrane treatment and which has an oxidation reduction potential ranging from +200 to +343 mV, a general mineralisation ranging from 25 to 130 mg/l and a pH value ranging from 6.9 to 8.3. The invention discloses a method for producing said agent, consisting in bringing watter to a drinking water state and in exposing said water to baromembrane treatment by the passage thereof through semipermeable membranes, the diameter of holes of which ranges from 0.0001-0.005 mkm. The invention also relates to a method for stimulating lymphatic drainage while treating patients having chronic skin diseases, non-oncological gastrointestinal tract diseases and chronic obstructive bronchitis, which method consists in taking said agent 30-40 minutes before and in 2-2.5 hour after each meal. The first dose is taken on an empty stomach. The inventive agent makes it possible to highly effectively stimulate the lymphatic drainage of the body tissue by enhancing lymph formation and transportation processes without any undesirable irritating effect.
Patent CA-2688068-A1 (CA)
Inventor: CONROY DAVID
IPC: B65D83/76
Filed: 2008-05-28
Abstract: An apparatus for dispensing material includes: a chamber for the material, the chamber sealed by a flexible seal; a nozzle coupled to the chamber and residing at a front end; and a pump, the pump comprising: a piston that moves in a tube, and an activator.. When a user presses the activator, the piston moves toward or away from the front end, and a portion of the material is emitted onto the user's palm or fingers. The pump emits the portion of the material regardless of a direction of gravitational pull. In one embodiment, the piston emits the material by directly contacting the material in the chamber. In another embodiment, air is allowed into the chamber through a weep hole, which resides between the piston and the material. The air is used to expel the material through the one-way valve.
Patent CA-2688898-A1 (CA)
Title: Electroconductive / peripheral nerve stimulated arthroscopic tools
Inventor: YEPES HORACIO
IPC: A61B17/32
Filed: 2009-12-11
Abstract: The current tools used by the Arthroscopic surgery are simple piecing devices that can not tell the surgeon if a nerve injury is imminent. Our idea is to modify some prototypes of existing arthroscopic tools adding the potential of being made with electro-conductive materials.   Our idea is to remake these tools with a bare naked proximal, and distal elecro-conductive tips. The proximal tip will allow connection of the tool with the connecting interface of a nerve stimulator cable. The distal one will get in contact with the tissue.  The tool shaft and handles shall be covered/ insolated with a non conductive material. As the tool is advanced by the surgeon though the tissue, an electro-conductive Arthroscopic tool, will alert the surgeon if a nerve injury is imminent.     Our idea is applicable to: 1- Suture passers/ Hooks.  2- Tissue dissector 3- Probes 4- Switching/sticks for arthroscopic cannulas 5- Meniscal repair needles 6- Arthroscopic Trocars 7- Banana knives/basket scissors
Patent CA-2689282-A1 (CA)
Inventor: LINDSLEY CRAIG W
IPC: A61K31/497
Filed: 2008-06-03
Abstract: In one aspect, the invention relates to compounds, including benzamide derivatives and cyclic benzamide derivatives, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Patent CA-2689644-A1 (CA)
Inventor: DORROS GERALD
IPC: A61F2/958
Filed: 2002-08-22
Abstract: Apparatus and methods for treatment of stroke are provided. In a preferred embodiment, the present invention disposes at least one catheter having a distal occlusive member in either the common carotid artery (CCA) or both the vertebral artery (VA) and the CCA on the hemisphere of the cerebral occlusion. Blood flow in the opposing carotid and/or vertebral arteries may be inhibited. Retrograde or antegrade flow may be provided through either catheter independently to effectively control cerebral flow characteristics.  Under such controlled flow conditions, a thrombectomy device may be used to treat the occlusion, and any emboli generated are directed into the catheter(s).
Patent CA-2690197-A1 (CA)
Title: Post-occlusion chamber collapse canceling system for a surgical apparatus and method of use
Inventor: ZACHARIAS JAIME
IPC: A61F9/007
Filed: 2008-06-19
Abstract: A post-occlusion chamber collapse canceling system for a surgical apparatus that detects the breaking of occlusions by tissue fragments in the distal end of the aspiration path and produces a response comprising a transitory blockage of the distal end the aspiration path to terminate the chamber collapse and a simultaneous transitory venting of the aspiration line to relieve the vacuum, in a way that post-occlusion chamber collapses are cancelled.  Disclosed herein, in a preferred embodiment, is a surgical system and related method for preventing collapse of a body chamber being operated upon, due to a vacuum surge following a clearing of an occlusion in an aspiration path of the surgical system, comprising: an occlusion-break sensor (300) for sensing the clearing of the occlusion; a normally-open occlusion valve (57), temporarily closing in response to the occlusion-break sensor sensing the clearing of the occlusion, thereby occluding fluid flow through the aspiration path and controllably stabilizing the occlusion break, thereby preventing the vacuum surge and consequent body chamber collapse;  and a normally- closed venting valve temporarily opening in response to the occlusion-break sensor sensing the clearing of the occlusion, to reduce the vacuum thereby preventing the vacuum surge and consequent body chamber collapse. In an alternative embodiment, the normally-open occlusion valve may be omitted.
Patent CA-2690529-A1 (CA)
Inventor: CARROTT RICHARD F
IPC: G06F21/00
Filed: 2007-09-04
Abstract: A system and method facilitates purchase transactions over a computer network, including the purchase of electronically storable items. The embodiments herein encrypt "customer information" in an encryption stream and cause the encryption stream to be transferred from the customer to a merchant in the purchase transaction. A verification entity receives the encryption stream which is sent by the merchant for identity verification and payment authorization. Then, the verification entity verifies the identifiers contained in the encryption stream and transfers an identity verification and payment authorization from the verification entity to the merchant. The encryption stream or unique transaction identifier can be added, by the merchant, to a purchased electronic item to create a personalized electronic item.
Patent CA-2690652-A1 (CA)
Title: Short-offset transient electromagnetic geophysical surveying
Inventor: ZIOLKOWSKI ANTONI MARJAN
IPC: G01V3/10
Filed: 2010-01-22
Abstract: A method for electromagnetic surveying subsurface formations includes inducing an electromagnetic field in the subsurface formations by passing electric current through a transmitter. Response of the subsurface formations to the induced electromagnetic field is detected at a first plurality of spaced apart positions disposed longitudinally within a bipole length of the transmitter. A direct induction response is removed from the detected response.
Patent CA-2692435-A1 (CA)
Title: Play set slide
Inventor: SAMMANN CHARLES CLIFTON
IPC: A63G21/04
Filed: 2008-07-11
Abstract: A slide assembly and method of assembling a slide assembly are disclosed for use in conjunction with a recreation structure. The slide assembly includes a pair of side rails with internal grooves along lengths thereof and a slide bed located between the side rails with side margins thereof received within the grooves of the side rails. The slide assembly also includes reinforcements extending between the side rails underneath the slide bed, with ends of each reinforcement received within a recess in each of the side rails. Fasteners, such as screws, selectively secure side margin portions of the slide bed and ends of each reinforcement to each of the side rails. The method of assembling a slide assembly includes inserting each side margin of a slide bed into grooves of the side rails and attaching the slide bed and side rails to a recreation structure.
Patent CA-2698001-A1 (CA)
Title: Dehumidifiers for high temperature operation, and associated systems and methods
Inventor: SCHNELLE TOM
IPC: F24F3/14
Filed: 2010-03-29
Abstract: Dehumidifiers for high temperature operation and associated systems and methods are disclosed. A method in accordance with a particular embodiment includes drawing air into a dehumidifier and automatically monitoring an electric current drawn by a refrigerant compressor of the dehumidifier. The method can further include automatically stopping the compressor in response to the current meeting or exceeding a predetermined threshold value, and automatically restarting the compressor in response to the compressor meeting a predetermined condition that includes or corresponds to a target pressure difference between refrigerant pressures upstream and downstream of the compressor. The predetermined condition, in at least some embodiments, includes the passage of a period of time sufficient to allow refrigerant pressures upstream and downstream of the compressor to come within a preselected range of each other.
Patent CA-2700634-A1 (CA)
Inventor: SUND WESLEY E
IPC: G05D7/06
Filed: 2002-11-25
Abstract: A recirculating fluid distribution system, comprising a fluid reservoir; a distribution conduit recirculating fluid through the fluid distribution system; a plurality of tool drops providing fluid from the reservoir to tools attached to the tool drops; a flow control device; a Coriolis mass flowmeter in fluid communication with the flow control device and the distribution conduit, the Coriolis flowmeter having a flow-tube of a high-purity plastic material and providing a output signal; a pressure transmitter in fluid communication with the Coriolis mass flowmeter and with the distribution conduit, the pressure transmitter providing an output signal; a controller receiving a setpoint signal, the controller receiving the output signals from the Coriolis flowmeter and the pressure transmitter and providing a control output signal to the flow control device, wherein the flow control device output varies in response to the control output signal to maintain a predetermined pressure and flow rate in the distribution conduit; a plurality of tool drop flow control devices, each in-line with a respective tool drop; and a plurality of tool drop Coriolis mass flowmeters, each in-line with a respective tool drop and each having a flow-tube made of a high-purity plastic material, and each providing an output signal; wherein the controller receives the output signals from the tool drop Coriolis mass flowmeters and provides control signals to the tool drop flow control devices.
Patent CA-2702670-A1 (CA)
Inventor: BRANDENBURGER ALLEN M
IPC: B65D5/42
Filed: 2010-04-28
Abstract: A carton for containing at least one article. The carton comprises a plurality of side panels extending at least partially around an interior of the carton. At least one of the plurality of side panels comprises a display feature. A plurality of bottom end flaps are respectively foldably connected to respective side panels of the plurality of side panels. The bottom end flaps at least partially form a closed bottom of the carton. A display panel is positioned in face-to-face relationship with the at least one of the plurality of side panels. The display panel is adjacent the display feature.
Patent CA-2703472-A1 (CA)
Inventor: MASON BARBARA
IPC: A61K31/197
Filed: 2008-10-27
Abstract: The present invention provides methods for treating alcohol dependence and preventing relapse in subjects in protracted alcohol abstinence. Also provided are methods for treating subjects suffering from cannabis dependence. Typically, these methods entail administering to the subjects in need of treatment a therapeutically effective amount of gabapentin, an analog of gabapentin, or pharmaceutically acceptable salt thereof.
Patent CA-2708400-A1 (CA)
Title: A slow-release formulation based on an association of glycogen and alginate
Inventor: RUSSO VINCENZO
IPC: A61K9/20
Filed: 2008-12-23
Abstract: The present invention relates to a controlled-release pharmaceutical formulation comprising at least one active in-gredient dispersed in a matrix comprising at least one slow-release excipient comprising an association of at least one glycogen and at least one alginate with alkaline-earth metal salts, and a process for its preparation. The invention also relates to a slow-release excipient comprising an association of at least one glycogen and at least one alginate with alkaline-earth metal salts, and the process for its preparation, and its use for the preparation of slow-release pharmaceutical formulations.
Patent CA-2708552-A1 (CA)
Inventor: KIM IN KYU
IPC: B60S1/04
Filed: 2010-06-25
Abstract: Disclosed is a method for controlling a wiper blade with heating elements embedded therein and coupled with a wiper arm of a vehicle to wipe a glass surface while moving together with the wiper arm. The method includes: detecting the operation or not of an engine of a vehicle; detecting the external temperature of the vehicle; and automatically supplying power to the heating elements based on the detected information on the operation of the engine and the temperature information.
Patent CA-2710186-A1 (CA)
Inventor: GOODYEAR MARK DAVIS
IPC: A61K39/02
Filed: 2008-12-04
Abstract: Heat treated bacterins, a method of producing heat treated bacterins, and porcine emulsion vaccines prepared from such heat treated bacterins are disclosed.
Patent CA-2710263-A1 (CA)
Inventor: MATSUMOTO SHINYA
IPC: F16H63/18
Filed: 2010-07-15
Abstract: A multistage transmission includes a lost motion mechanism for regulating the operation for a downward shift in acceleration and for an upward shift in deceleration. Regulating rods are integrally moved with a control rod.  A cutout into which a pin can be fitted together with a cam groove of the slidingly touched cam rod is formed corresponding to each cam groove in the regulating rods. The cutout of the regulating rods corresponding to the cam groove of the cam rod for normal rotation is formed longer than the corresponding cam groove on the reverse side to a moving direction of the control rod in an upward shift in a state in which shifted speed is established.  The cutout of the regulating rods corresponding to the cam groove of the cam rod for reverse rotation is formed longer than the corresponding cam groove on the reverse side to a moving direction
Patent CA-2710717-A1 (CA)
Inventor: SAVOIE RICHARD
IPC: A61M5/168
Filed: 2010-07-21
Abstract: Provided is a wearable, self-contained drug infusion or medical device capable of communicating with a host controller or other external devices via a personal area network (PAN). The medical device utilizes a PAN transceiver for communication with other devices in contact with a user's body, such as a physiological sensor or host controller, by propagating a current across the user's body via capacitive coupling. The wearable nature of the medical device and the low power requirements of the PAN communication system enable the medical device to utilize alternative energy harvesting techniques for powering the device. The medical device preferably utilizes thermal, kinetic and other energy harvesting techniques for capturing energy from the user and the environment during normal use of the medical device. A system power distribution unit is provided for managing the harvested energy and selectively supplying power to the medical device during system operation.
Patent CA-2713066-A1 (CA)
Inventor: MUNOZ EMILIO A
IPC: A61H23/04
Filed: 2010-08-12
Abstract: A mobile leg constriction apparatus for promoting blood circulation is disclosed. The leg constriction apparatus includes a first cylindrically-shaped inflatable element for surrounding a patient's thigh, a second cylindrically-shaped inflatable element for surrounding the patient's calf, a first tube for connecting the first inflatable elements to an air pump and a second tube for connecting the second inflatable elements to the air pump. The leg constriction apparatus further includes an enclosure comprising an air pump for inflating the first and second inflatable elements. The leg constriction apparatus further includes one or more pressure sensors for measuring air pressure within the first and second tubes, one or more escape valves for allowing air to escape from the first and tubes and a processor configured for receiving information from the one or more pressure sensors and initiating inflation and deflation of the first and second inflatable elements according to a predefined profile.
Patent CA-2713267-A1 (CA)
Inventor: PREUSCHEN JUDITH
IPC: C11D3/37
Filed: 2009-01-23
Abstract: The present invention relates to compositions comprising polyaspartic acid (PAS) derivatives and the use of said compositions in washing processes, especially in automatic dishwashing.
Patent CA-2714154-A1 (CA)
Inventor: BRISSENDEN DAVE
IPC: A43B23/00
Filed: 2010-08-27
Abstract: There is provided a tag for attachment to a shoe having shoelaces. The shoe is a standard laced shoe having a pair of opposing retainers which are configured to be secured together by a shoelace threaded through a plurality of lace passages formed on the opposing retainers. The tag includes a web having an upper and lower edge and a plurality of lace retainers configured to receive the shoelace there through. At least one lace retainers is formed on the web adjacent each of the upper and lower edges of the web. The web is dimensioned to permit the tag to be attached between the opposing retainers by threading the shoelace through the lace retainers. The web is further dimensioned to fit between the lace passages of the opposing retainers. The lace retainers preferably consist of grommets and the web is preferably a flexible web having four corners with a grommet positioned adjacent each of the corners. The tag has a display surface upon which an insignia is displayed. The tag is preferably dimensioned to permit the tag to rest flat against the shoe with the display surface oriented away from the shoe.