baber/WOPTO huggingface dataset:
Patent CA-3136147-A1 (CA)
Inventor: ASOKAN MANGAIARKARASI
IPC: C07K16/28
Filed: 2020-04-08
Abstract: Using the Cross-Over-Dual-Variable Domain (CODv) format, the present disclosure relates to compositions comprising trispecific and/ or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more HIV target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation, and wherein a second pair of polypeptides possess a single variable domain. Also provided herein are methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins for the treatment and/or prevention of HIV/AIDS.
Patent CA-3136657-A1 (CA)
Title: Dispositif d'elimination par rotation de parasites de type acarien
Inventor: STEHR ISABELL KERSTIN
IPC: A46B13/02
Filed: 2020-04-08
Abstract: La présente invention concerne un dispositif (1) pour éliminer un parasite de type acarien, en particulier une tique, qui a pénétré dans la peau d'un hôte, ledit dispositif comprenant un entraînement (5), en particulier un entraînement électromoteur, logé dans un boîtier (2), et une pièce rapportée (3, 3a) qui présente une interface (10) du côté de l'entraînement, qui peut tourner autour d'un axe de rotation (D) et qui comprend un certain nombre de fibres (20), disposées à la manière d'une brosse, en tant qu'agencement de fibres (3b), ledit agencement de fibres (3b) présentant un évidement (19), en particulier un évidement conique, tronconique ou parabolique, de préférence coaxial, et un agencement de couronne de fibres formée par les fibres (20) à leurs extrémités sans fibres sur la périphérie de l'évidement (19) et présentant au moins une couronne de fibres (Fn) ayant une largeur (b) supérieure ou égale à 0,3 mm, de préférence (0,8 ± 0,4) mm.
Patent CA-3138787-A1 (CA)
Inventor: THOMPSON CHRISTOPHER
IPC: F16L27/08
Filed: 2020-06-02
Abstract: A sealed joint assembly for transmitting high temperature and high pressure fluid between adjoining ducts, the joint assembly comprising: a gimbal ring (200); a first clevis (100) comprising an annular shroud adapted for positioning concentrically within a portion of the gimbal ring, and at least two lobes (110) integrally formed with the shroud, each lobe extending radially outward and axially over a portion of the gimbal ring, and wherein each lobe includes one or more gaps (114) to produce a shear web of interconnected trusses extending across the lobe; a second clevis (150) comprising an annular shroud adapted for positioning concentrically within a portion of the gimbal ring, and at least two lobes (160) integrally formed with the shroud, each lobe extending radially outward and axially over a portion of the gimbal ring, and wherein each lobe includes one or more gaps (164) to produce a shear web of interconnected trusses extending across the lobe; and a bellows having a first end and a second end, said first end being sealedly coupled to the first clevis(100), and said second end being sealedly coupled to the second clevis (150).
Patent CA-3141598-A1 (CA)
Inventor: ZHAI XIAOQING
IPC: G06F16/24
Filed: 2021-09-24
Abstract: Disclosed in the present invention are a method, a device, and a system for generating multi-dimension data cubes. The mentioned method comprises: collecting the query data from an analytical engine including model infomiation, dimension information, metric information, and time granularity associated with the described query; statistically analyzing the mentioned query data to determine construction information for a multi-dimensional data cube, including recommending models, recommending dimension combinations, recommending metrices, and recommending time granularity; and generating the multi-dimensional data cube according to the mentioned construction infomiation. The technical strategies provided in the present invention allows the automatic Cube generation, to solve the problems of possible dimension loss, time granularity mismatching, and low Cube hit rate in the manually created Cube.
Patent CA-3142481-A1 (CA)
Title: Medical/dental/utility glove with anti-fatigue and air channel improvements
Inventor: ANSTEY PAUL
IPC: A41D19/04
Filed: 2020-06-02
Abstract: The present invention is to an improved elastomeric glove having stress relief zones to reduce user fatigue. The glove may have stress relief areas between and over some or all of the joints, knuckles and bones of the hand, wherein the relief zones are formed of asymmetrical or symmetrical humps. Alternatively, these raised relief zone areas are formed of asymmetrical or symmetrical diamond shaped or frusto-diamond shaped zones. A relief zone can also be provided over the webbing between the thumb and the palm. A relief zone can also be provided over the soft tissue webbing between the thumb and the forefinger on the dorsal and ventral surface of the hand. The diamond/humped shaped relief zones provide for improved(consistent) glove function and quality while keeping manufacturing challenges and costs to a minimum.
Patent CA-3142855-A1 (CA)
Title: Improved vaccine formulations
Inventor: SAINT-REMY JEAN-MARIE
IPC: A61K35/17
Filed: 2020-06-29
Abstract: A pharmaceutically compatible antioxidant for use in the treatment or the prevention of an unwanted immune response, the corresponding pharmaceutical and vaccine compositions, and the corresponding clinical and ex-vivo applications.
Patent CA-3145154-A1 (CA)
Inventor: MALIK DANISH
IPC: A61K48/00
Filed: 2020-06-26
Abstract: A process for the preparation of unilamellar vesicles, wherein a a unilamellar vesicle comprises an amphiphilic membrane enclosing an aqueous core; and compositions comprising unilamellar vesicles. The process comprises providing a primary emulsion comprising an amphiphilic membrane forming component, a first aqueous phase W1 and a first oil phase O1. The first aqueous phase W1 is dispersed as droplets in the oil phase O1 such that the primary emulsion is a water-in-oil emulsion. The primary emulsion comprises droplets having a mean diameter of less than 1000nm. The process comprises combining the primary emulsion with a second aqueous phase W2 to produce a secondary emulsion that is a water-in-oil-in-water emulsion; dewetting to yield unilamellar vesicles in the secondary emulsion; and isolating the unilamellar vesicles.
Patent CA-3145254-A1 (CA)
Title: Method of contextual speech decoding from the brain
Inventor: CHANG EDWARD F
IPC: A61B5/372
Filed: 2020-07-27
Abstract: Provided are methods of contextual decoding and/or speech decoding from the brain of a subject. The methods include decoding neural or optical signals from the cortical region of an individual, extracting context-related features and/or speech-related features from the neural or optical signals, and decoding the context-related features and/or speech-related features from the neural or optical signals. Contextual decoding and speech decoding systems and devices for practicing the subject methods are also provided.
Patent CA-3146173-A1 (CA)
Inventor: VENTRELLA ALFREDO
IPC: G02B6/38
Filed: 2020-07-10
Abstract: La présente invention concerne un dispositif adaptateur femelle de sécurité pour connexions de fibres optiques, conçu pour loger un connecteur optique mâle, caractérisé en ce qu'il comprend des moyens de verrouillage à libération contrôlée conçus pour contraindre un coulissement longitudinal du connecteur mâle par rapport au dispositif adaptateur femelle, lorsque le connecteur est inséré dans le dispositif adaptateur pour établir la connexion optique, et libérer le coulissement longitudinal du connecteur par rapport au dispositif adaptateur, pendant l'insertion ou la déconnexion du connecteur mâle dans/à partir du dispositif adaptateur femelle.
Patent CA-3146891-A1 (CA)
Title: Diones cycliques en tant que composes herbicides
Inventor: HENNESSY ALAN JOSEPH
IPC: C07D241/24
Filed: 2020-07-27
Abstract: La présente invention concerne des composés de formule (I), dans laquelle R1, R2, R3, R4x, R4y, m, n et G sont tels que définis dans la description. L'invention concerne en outre des compositions herbicides comprenant un composé de formule (I), et leur utilisation pour lutter contre les mauvaises herbes, en particulier dans des cultures de plantes utiles.
Patent CA-3146979-A1 (CA)
Inventor: CHEN HONGLING
IPC: G06T7/00
Filed: 2020-07-10
Abstract: Système et procédé de fourniture d'informations textiles et visualisation de ceux-ci. Le procédé de détermination d'un niveau d'endommagement d'un textile comprend : la réception d'une image d'au moins une partie d'un textile (S301) ; la réception d'informations concernant un type de tissu du textile (S302) ; l'identification d'un attribut de tissu du textile (S303) ; la détermination d'une valeur de gravité (S304) ; la détermination d'un niveau d'endommagement du textile (S305).
Patent CA-3148002-A1 (CA)
Inventor: SILVENTE STEPHANE
IPC: A61K31/575
Filed: 2020-07-24
Abstract: Disclosed is a composition comprising sterol derivatives for use in the treatment of a neuronal pathology related to hypoxia, hypoglycemia and/or hyperglycemia affecting cells of the central nervous system.
Patent CA-3152841-A1 (CA)
Title: Telehander with facilitated ascent and descent
Inventor: IOTTI MARCO
IPC: B66C13/52
Filed: 2022-03-21
Abstract: Described is a telehandler equipped with a carriage movable on wheels and a driver's cab (1), located above the carriage, which comprises an access door (10) equipped with two side jambs (11, 12), to each of which is fixed a continuous handle (2, 3) the length of which is greater than half the length of the respective jamb (11, 12).
Patent CA-3154869-A1 (CA)
Title: System health status predicting method, device, computer equipment and storage medium
Inventor: NI GUOPING
IPC: G01D21/00
Filed: 2022-04-11
Abstract: The present application relates to a system health status predicting method, and corresponding device, computer equipment and storage medium. The method comprises: obtaining current health curve of system within a current time window; selecting corresponding target health curve from historical health curves of system according to current health curve, and calculating time difference between a time window in which the target health curve resides and current time window; taking any time interval following current time window as prediction time interval; and predicting health status of system within prediction time interval through health status of system in a target historical time interval, wherein target historical time interval is a historical time interval that is before the prediction time interval and differs from the prediction time interval by the time difference. Use of this method enables precognition of health status of system, and enhancement of the timeliness of system health status analysis.
Patent CA-3155142-A1 (CA)
Inventor: KAI HIROYUKI
IPC: A61P9/12
Filed: 2020-09-18
Abstract: L'invention concerne : un cristal d'un dérivé de 1,3,5-triazine ou un solvate de celui-ci ; et un procédé de production de celui-ci. La présente invention concerne un cristal d'un composé représenté par la formule (I) ou un solvate de celui-ci, et une composition pharmaceutique le contenant. La présente invention concerne également un procédé de production d'un cristal d'un composé représenté par la formule (I) ou un solvate de celui-ci.
Patent CA-3155616-A1 (CA)
Inventor: LIU TUANFANG
IPC: A24F40/40
Filed: 2022-04-19
Abstract: A heating element includes a main body. The main body includes a thermal air chamber and at least one through hole communicating with the thermal air chamber.
Patent CA-3156504-A1 (CA)
Title: Instrumentation for fusing a sacroiliac joint
Inventor: LANEVE SEAN
IPC: A61F2/44
Filed: 2020-10-05
Abstract: An apparatus for installing a fusion implant (5) into the sacroiliac joint (3) ("SI Joint"). The apparatus comprises a working channel (10), a joint locator (20), an abrading device (30), and an insertion device (60). The joint locator (20) is inserted into the working channel (10), and this combination, guided by a K-wire (4), is advanced into the SI Joint (3). The joint locator (20) is removed, and the abrading device (30) is used to abrade the sacrum (1) and ilium (2) inside the SI Joint (3). The insertion device (60) then advances the implant (5) into the abraded area of the SI Joint (3). The abraded area heals across the implant (5), thereby fusing the sacrum (1) to the ilium (2) and fusing the SI Joint (3).
Patent CA-3161982-A1 (CA)
Title: Dissolvable polymeric eye inserts with a biodegradable polymer
Inventor: KETELSON HOWARD ALLEN
IPC: A61K9/00
Filed: 2020-12-08
Abstract: A polymeric eye insert, the insert comprising: a biodegradable polymer and one or more mucoadhesive polymers that are biocompatible with the ocular surface and tear film of the eye; wherein the biodegradable polymer increases a dissolution time of the polymeric eye insert by at least 15 percent comparing to the control polymeric eye insert which is the same polymeric eye insert except the biodegradable polymer is not present.
Patent CA-3162246-A1 (CA)
Title: Compositions anti-muc1 et methodes d'utilisation
Inventor: OSTERTAG ERIC M
IPC: C07K14/725
Filed: 2020-12-18
Abstract: Sont divulgués, des anticorps contre la MUC1, des compositions de MUC1-CAR et des méthodes d'utilisation de ces anticorps pour cibler une protéine MUC1, une cellule exprimant la protéine MUC1 ciblée pouvant être ciblée et éliminée, par exemple, par un lymphocyte T cytotoxique.
Patent CA-3162823-A1 (CA)
Inventor: SANCHO DURA JUAN
IPC: A61B18/00
Filed: 2021-01-13
Abstract: L'invention concerne des systèmes et des procédés pour effectuer une analyse de signal optique et des prédictions de lésion dans des ablations. Un système comprend un cathéter accouplé à une pluralité de fibres optiques par l'intermédiaire d'un connecteur qui s'interface avec un dispositif informatique. Le dispositif informatique comprend une mémoire et un processeur configurés pour recevoir des données de mesure optique d'une partie de tissu provenant du cathéter. Le processeur identifie une ou plusieurs propriétés optiques de la partie de tissu par analyse des données de mesure optique et détermine un temps de dénaturation de la partie de tissu sur la base de la ou des propriétés optiques. Un modèle est créé pour représenter une corrélation entre des profondeurs de lésion et des temps d'ablation à l'aide du temps de dénaturation, de la ou des propriétés optiques et de la période de temps prédéterminée. Une profondeur de lésion prédite pour un temps d'ablation prédéterminé est générée à l'aide du modèle.
Patent CA-3162958-A1 (CA)
Title: Reactive conjugates
Inventor: NYANGUILE ORIGENE FRANZ
IPC: A61K49/00
Filed: 2020-12-03
Abstract: The present invention relates to compounds (reactive conjugates) for the chemical modification of therapeutic antibodies or proteins. The compounds enable the regioselective attachment of a payload to an antibody or antibody fragment in one single step, thereby producing a modified antibody or modified antibody fragment, which can be used for diagnosing, monitoring, imaging or treating disease.
Patent CA-3165126-A1 (CA)
Inventor: BHARWANI KIRAN KUMAR RAM
IPC: G01C21/28
Filed: 2022-06-23
Abstract: Disclosed embodiments include systems, vehicles, and computer-implemented methods for logging positional coordinates and additional data for an unmapped route. In an illustrative embodiment, a system includes a computing device including: a positioning system configured to determine positional coordinates of the positioning system; a processor; and computer-readable media configured to store computer-executable instructions configured to cause the processor to: responsive to determining that the positional coordinates indicate that the positioning system is operating on an unmapped route that is not included in existing map data accessible by the processor, log the positional coordinates for each of a plurality of points along the unmapped route in a new map data set; log additional data for at least a portion of the unmapped route in the new map data set; and communicate the new map data set to a remote data store from which another user can access the new map data.
Patent CA-3165672-A1 (CA)
Inventor: NOMURA NARUHIKO
IPC: B21D22/20
Filed: 2021-03-19
Abstract: The die (10) includes a die base (12), a die body (11), and an opening/closing member (13). In the die base (12), a storage portion (122) for storing refrigerant is formed. The die body (11) includes a mounting surface (112), a forming surface (111), and a plurality of flow channels (113). The mounting surface (112) is located on the storage portion (122) side of the die base (12). The forming surface (111) is located on the opposite side of the mounting surface (112). The plurality of flow channels (113) pass through the die body (11) from the mounting surface (112)to the forming surface (111). The opening/closing member (13) is disposed between the die base (12) and the die body (11). The opening/closing member (13) includes a plurality of through holes (131) corresponding to the plurality of flow channels (113). The opening/closing member (13) is configured to be movable with respect to the die base (12) and the die body (11) such that each of the through holes (131) brings the corresponding flow channel (113) and the storage portion (122) into communication.
Patent CA-3166846-A1 (CA)
Title: Medical device with adaptive correction for uncontrollable delivery conditions
Inventor: OOI CHUN KEAT
IPC: G16H40/60
Filed: 2022-07-06
Abstract: An infusion device is configured to monitor delivery conditions associated with a medication infusion, identify an infusion set used with the infusion device, determine that the delivery conditions modify operation of infusion set, and determine correction factors for modifying an operation of the device based on a modification of the operation of the infusion set by the monitored delivery conditions. According to various implementations, an operating parameter of the infusion device may be modified, including modifying a threshold for when the infusion device will experience an alarm condition.
Patent CA-3167310-A1 (CA)
Title: Wall supported scaffolding system
Inventor: SULLIVAN WILLIAM DAVID
IPC: E04G5/06
Filed: 2022-07-11
Abstract: A system and method for forming a scaffolding wherein the system comprises at least one bracket securable to a vertical surface of a building, a horizontal support member supported by the at least one bracket, the support member adapted to support a worker support platform on a horizontal support surface thereof and a flexible retaining member adapted to pass over a worker support platform supported on the horizontal support member so as to retain the worker support platform on the horizontal support surface. The method comprises securing at least one bracket to the a building, supporting a worker support platform on a horizontal support member and retaining the worker support platform on the horizontal support member with the flexible retaining member.
Patent CA-3168571-A1 (CA)
Title: Production of soluble recombinant protein
Inventor: CHANG MIN-JU
IPC: A61P31/04
Filed: 2021-03-12
Abstract: The invention is directed to methods and compositions for the expression and purification of products such as peptides and proteins in microorganisms. In particular, pre-products are expressed recombinantly, wherein the cytoplasm of the microorganism alters the expressed pre-products to produce products in an active/final or otherwise desirable form. Alterations associated with expression of a desired recombinant product include shifting of the redox state of the cytoplasm to allow proper protein folding, site-directed cleavage of pre-proteins to activate the protein, site-directed cleavage of an unwanted methionine from the N terminus of the protein, and/or one or more ligations to form desired protein configurations, all within the same cell.
Patent CA-3171524-A1 (CA)
Inventor: BRUNEAU SAMUEL
IPC: B60K35/00
Filed: 2022-08-26
Abstract: Systems and methods for facilitating travel of an electric off-road vehicle on an uncharted off-road route are provided. A method includes relating the uncharted off-road route to be travelled by the electric off-road vehicle to map data of a geographic area including the uncharted off-road route. Using the map data, one or more geographic characteristics of the uncharted off-road route are determined. Using the one or more geographic characteristics of the uncharted off-road route and predetermined battery consumption data associated with the one or more geographic characteristics, an estimated battery consumption for the electric off-road vehicle to travel the uncharted off-road route is determined. The estimated battery consumption is communicated to an operator of the electric off-road vehicle.
Patent CA-3171910-A1 (CA)
Inventor: DOCHERTY CONNOR JAMES
IPC: F04B53/10
Filed: 2021-03-23
Abstract: A valve seat for a valve assembly for a high-pressure fluid pump is disclosed. The valve assembly includes a valve body, and a valve seat fabricated of a first material. The valve seat has a generally a tubular body having an annular collar having an outer diameter surface extending beyond the outer diameter surface of the tubular body, and an annular insert fabricated of a second material more durable than the first material and affixed to form an inner diameter surface of the collar, the insert forming an annular sealing surface against which the valve body abuts when in a closed position. The insert forms an annular ledge edge at its inner diameter surface that is offset from the inner diameter surface of the tubular body to form an annular chamfered edge.
Patent CA-3173845-A1 (CA)
Title: Use of exosome-based delivery of nf-kb inhibitors
Inventor: CHOI CHULHEE
IPC: C12N5/073
Filed: 2021-03-31
Abstract: The present disclosure relates to methods for treating acute kidney injury using exosome containing NF-?B inhibitors. The present disclosure relates to methods for treating diseases induced by sepsis using exosome containing NF-?B inhibitor.
Patent CA-3176636-A1 (CA)
Title: Disposable indicator component for measuring analyte concentration in bodily fluids
Inventor: BINNER CURT
IPC: A61B10/00
Filed: 2021-03-22
Abstract: A disposable indicator component for use in a system for measuring analyte concentration in a bodily fluid includes an indicator zone comprising at least one colorimetric analyte sensing element, and a coupler for coupling the indicator component to a component having at least one spectrophotometer contained within a housing.
Patent CA-3181352-A1 (CA)
Title: Transglutaminase variants and applications of use thereof
Inventor: SHINDEL WILLIAM
IPC: C12N15/52
Filed: 2021-05-13
Abstract: Variants of the transglutaminase enzyme of Streptomyces mobaraensis are provided. The disclosed variants exhibit at least about 2-fold increased enzymatic activity versus the wild-type enzyme. Methods and compositions are provided for biocidal applications of use and for covalently binding small organic molecules to a protein or material of interest. Methods are provided for increasing the self-life of products, such as personal care, household and industrial products, by incorporating an effective amount of the disclosed variant enzymes into the product. The transglutaminase variants may also be used to covalently bind functional ingredients, such as UV-blocking molecules, dyes, or pigments to proteins. The transglutaminase enzymes and functional ingredients may be incorporated into a cosmetic formulation for modifying skin, hair, or nail proteins or skin-derived proteins, such as collagen, keratin, and/or elastin.