baber/WOPTO huggingface dataset:
Patent WO-2019161304-A1 (WO)
Title: Gene editing using homology-independent universal genome engineering technology
Inventor: GAO YUDONG
IPC: A61K38/46
Filed: 2019-02-15
Abstract: Disclosed herein are the genetic constructs for a Homology-Independent Universal Genome Editing (HiUGE) system and methods of using said HiUGE system for genome editing. The invention relates to compositions comprising gRNA polynucleotides, insert polynucleotides, and a CRISPR-based nuclease or polynucleotide encoding a CRISPR-based nuclease.
Patent WO-2019165460-A1 (WO)
Title: Method and apparatus for improving integrity of processor voltage supply with support for dvfs
Inventor: GELMAN ANATOLY
IPC: G06F1/30
Filed: 2019-02-26
Abstract: Dedicated circuitry may monitor a processor supply voltage and provide additional power on a temporary nano-second scale basis to the processor when the supply voltage drops below predetermined levels. This may be done without explicit knowledge of a commanded supply voltage level for the processor.
Patent WO-2019134007-A1 (WO)
Inventor: KIMBALL CORY
IPC: A61B17/02
Filed: 2019-02-28
Abstract: La présente invention concerne divers systèmes et procédés pour commander l'activation d'instruments chirurgicaux à énergie. Un instrument chirurgical à énergie avancé, tel qu'un instrument électrochirurgical ou un instrument chirurgical à ultrasons, peut comprendre un ou plusieurs ensembles capteurs pour détecter l'état ou la position de l'effecteur terminal, du bras ou d'autres composants de l'instrument chirurgical. Un circuit de commande peut être conçu pour commander l'activation de l'instrument chirurgical en fonction de l'état ou de la position des composants de l'instrument chirurgical.
Patent WO-2019199554-A1 (WO)
Title: Multi-microphone speech separation
Inventor: CHEN ZHUO
IPC: G10L15/16
Filed: 2019-04-04
Abstract: This document relates to separation of audio signals into speaker-specific signals. One example obtains features reflecting mixed speech signals captured by multiple microphones. The features can be input a neural network and masks can be obtained from the neural network. The masks can be applied one or more of the mixed speech signals captured by one or more of the microphones to obtain two or more separate speaker-specific speech signals, which can then be output.
Patent WO-2019204047-A1 (WO)
Title: Utilization based dynamic resource reallocation using two thresholds and a time window
Inventor: HASSAN AMER A
IPC: G06F9/50
Filed: 2019-04-05
Abstract: Methods and systems disclosed provide for dynamically allocating resources based on a utilization of a computing resource, such as a network or a stable storage device. In one aspect, a system including processing circuitry configured to perform operations, the operations including determining, at a first time, a utilization spike of a computing resource based on a utilization threshold, automatically adjusting the utilization threshold based on the determination, determining, during a time window, one or more second utilization spikes of the computing resource based on the adjusted utilization threshold; and dynamically reallocating resources in response to the determined one or more second utilization spikes meeting a first criterion.
Patent WO-2019204434-A1 (WO)
Title: Compositions and methods for modulating permeability of biological barriers
Inventor: WHITEHEAD KATHRYN
IPC: A61K31/36
Filed: 2019-04-17
Abstract: A method of reversibly increasing intestinal epithelium permeability is provided. A plant polyphenol composition, such as a pelargonidin-containing composition is enterically-administered, e.g., with a high molecular weight therapeutic agent, such as insulin, such that therapeutic agents having high molecular weights can be delivered enterically. An oral dosage form for enteric delivery of high molecular weight therapeutic agents also is provided.
Patent WO-2019217459-A1 (WO)
Inventor: NAIR JAYAPRAKASH K
IPC: C12N15/11
Filed: 2019-05-07
Abstract: L'invention concerne un procédé de silençage génique, comprenant l'administration à une cellule ou à un sujet qui en a besoin d'une quantité thérapeutiquement efficace des ARNi à double brin conjugués à des fractions lipophiles au niveau d'une ou de plusieurs positions internes sur au moins un brin, éventuellement par l'intermédiaire d'un lieur ou d'un support.
Patent WO-2019231993-A1 (WO)
Inventor: RENGER JOHN J
IPC: A61K31/485
Filed: 2019-05-29
Abstract: L'invention concerne divers systèmes d'administration de médicament, des compositions pharmaceutiques, des formes posologiques, et des kits pour fournir un sauvetage de surdose d'opioïde à un patient ainsi qu'un procédé pour fournir un sauvetage de surdose d'opioïde à un patient. Les systèmes d'administration de médicament, les compositions pharmaceutiques, les formes posologiques et les kits peuvent comprendre un antagoniste opioïde et un agent antipsychotique.
Patent WO-2019236645-A1 (WO)
Title: Automated and dynamically adjustable gas mixer for bioreactor system
Inventor: CATTARUZZI GIACOMO
IPC: C12M1/34
Filed: 2019-06-05
Abstract: A gas mixer system includes a first line carrying a first gas component, and a first flow rate controller adapted to receive data relating to a measure of a first parameter and adjust a first flow rate of the first gas component based on the measure of the first parameter. The gas mixer system also includes a second line carrying a second gas component, and a second flow rate controller adapted to receive data relating to a measure of a second parameter and adjust a second flow rate of the second gas component based on the measure of the second parameter. The gas mixer system further includes a vessel connected to the first and second flow rate controllers, wherein the first gas component and the second gas component are mixed in the vessel to produce a gas mixture, and at least one outlet port. For example, the gas mixer may be connected to and provide a gas mixture to a bioreactor.
Patent WO-2019246440-A1 (WO)
Title: Ensemble amortisseur de chocs
Inventor: RUSSELL PETER
IPC: F16F9/348
Filed: 2019-06-20
Abstract: Cette invention concerne un amortisseur de chocs, comprenant un cylindre, une tige de piston, un corps de piston et une soupape. Le cylindre est configuré pour recevoir un fluide. Le corps de piston est relié à la tige de piston et est configuré pour effectuer un mouvement de va-et-vient à l'intérieur du cylindre entre une chambre de compression et une chambre de retour. La soupape est fournie par le corps de piston ayant un orifice d'écoulement de fluide, un siège de soupape, un élément de soupape circonférentiel, et un ressort conçu pour pousser le corps de soupape dans le siège de soupape. L'invention concerne en outre une soupape d'amortissement principale et une soupape d'amortissement auxiliaire.
Patent WO-2020023176-A1 (WO)
Title: System, method and apparatus for monitoring wireless communications
Inventor: RAJENDIRAN SUBRAMANI
IPC: H04W24/06
Filed: 2019-06-27
Abstract: A system for monitoring wireless communications in a client device includes a wireless communications interface, including: an analyzer; a monitoring controller coupled to the analyzer; an operational controller of the client device coupled to the wireless communications interface, the operational controller configured to: control the wireless communications interface to establish a wireless connection with an access point according to a set of connection parameters including a channel identifier; and transmit the set of connection parameters to the monitoring controller; the monitoring controller configured, responsive to receiving the connection parameters from the operational controller, to: monitor a channel corresponding to the channel identifier to obtain a plurality of frames transmitted over the channel; and provide the plurality of frames to the analyzer.
Patent WO-2020027961-A1 (WO)
Title: A system and a method for monitoring engine conditions
Inventor: GALBREATH ROLAND
IPC: F02D41/00
Filed: 2019-06-28
Abstract: A system and a method for preventing a boat fire. Such a system and method may sense fumes in an engine of a boat (or other system that includes an engine), alert the boat operator and inhibit the engine or engines from starting. Also, the system and method allow for a bypass of the system in the event of false alarm and warn with alarm prior to expiration of the life time for fume sensors. Further, in a case where an onboard generator is used in boats, the system and method shutdown the generator upon a signal from a carbon dioxide detector providing immediate cessation of carbon dioxide producer.
Patent WO-2020009957-A1 (WO)
Title: Glass-based articles with improved stress profiles
Inventor: SCHNEIDER VITOR MARINO
IPC: C03C21/00
Filed: 2019-07-01
Abstract: Glass-based articles are manufactured by a unique ion exchange process that results in glass-based articles having improved stress profiles with higher stress values at moderate depths. A medium of the ion exchange process includes ions of two or more alkali metals of two or more alkali metal oxides in a base composition of a glass-based substrate in a ratio such that ions of each alkali metal are in chemical equilibrium with each of the respective alkali metals of the alkali metal oxides in the base glass composition.
Patent WO-2020010038-A1 (WO)
Inventor: YATES KENNETH
IPC: A61P1/02
Filed: 2019-07-02
Abstract: Une solution de rinçage buccal comprenant de l'argent ionique en tant que complexe de citrate d'argent et de l'acémannane est utile pour le traitement de l'ulcération buccale et de la mucosite buccale. La solution de rinçage buccal a démontré une efficacité contre des espèces fongiques et bactériennes telles que l'espèce Candida, Staphylococcus aureus et Streptococcus pyogenes.
Patent WO-2021002854-A1 (WO)
Title: Systèmes et procédés de tri de vêtements
Inventor: ALSOP DANNY E
IPC: B07C7/00
Filed: 2019-07-02
Abstract: L'invention concerne divers agencements impliquant un système de tri de vêtements. Le système de tri de vêtements peut comprendre une plate-forme pour permettre à un opérateur de monter dessus. Le système de tri de vêtements peut comprendre un transporteur circulaire qui tourne dans le sens des aiguilles d'une montre ou dans le sens inverse des aiguilles d'une montre pour déplacer le flux d'articles sans fin autour de la plate-forme jusqu'à ce que lesdits articles soient retirés par l'opérateur. Le système de tri de vêtements peut comprendre une pluralité de goulottes de collecte d'articles vestimentaires disposées selon un motif circulaire autour d'une circonférence extérieure du transporteur circulaire.
Patent WO-2020014092-A1 (WO)
Title: Recirculation water heater for bathtub
Inventor: LIN CHANG-TSUNG
IPC: F24H1/00
Filed: 2019-07-07
Abstract: A recirculation water heater system is provided as an add-on device for household non-heated bathtubs to solve the temperature maintenance issue. This add-on device can draw and recirculate water from the bathtub to warm up and thereby maintain the temperature of the water.
Patent WO-2020033185-A1 (WO)
Title: Distributed channel access mechanism using multiple access signatures for control transmissions
Inventor: GULATI KAPIL
IPC: H04L1/16
Filed: 2019-07-30
Abstract: Aspects of the disclosure relate to a distributed channel access mechanism using multiple access (MA) signatures for control transmissions. In one aspect, a transmitting device determines a MA signature for distinguishing a transmission of the transmitting device from another transmission of another transmitting device on a same frequency resource, transmits sidelink control information using the MA signature on a first set of frequency resources, the sidelink control information corresponding to first data information transmits the first data information on the first set of frequency resources, and receives, from a receiving device, a response indicating whether reception of the first data information was successful. Other aspects, embodiments, and features are also claimed and described.
Patent WO-2020041714-A1 (WO)
Title: Planetary gear system
Inventor: DEVREESE THIBAULT
IPC: F16H57/08
Filed: 2019-08-23
Abstract: A planetary gear system including a first gear coupled to a shaft, a plurality of second gears in rotational engagement with the first gear, a fluid supply apparatus spaced apart from the second gears, and a carrier. The carrier includes an annular portion having a flow channel configured to receive a fluid deposited onto the carrier by the fluid supply apparatus. A pinion shaft is disposed through each of the second gears and includes a primary fluid conduit in fluid communication with the flow channel and at least one secondary fluid conduit in fluid communication with the primary fluid conduit. The primary fluid conduit and the at least one secondary fluid conduit facilitate a flow of the fluid from the flow channel to at least one bearing disposed on each of the pinion shafts and at least one thrust plate interposed between the second gears and the carrier.
Patent WO-2020072636-A1 (WO)
Title: Composition and methods for treating acute diarrhea and enteric
Inventor: SCHULTZ THOMAS
IPC: A61K9/00
Filed: 2019-10-02
Abstract: The composition may be used therapeutically or prophylactically and is directed toward a cluster of diarrhea-causing pathogens which cause illness or death in animals, including dogs and cats. It is prepared from a powdered egg preparation and powdered protein matrix, such as bovine colostrum. The eggs are collected from hens which have been immunized with the relevant pathogens or toxins. When the matrix includes colostrum, the powdered colostrum is derived from non-hyperimmune cattle. The vaccination strategy includes the use of antibody cross-reactivity between toxins or pathogens which cause diarrhea. For some diseases, including canine parvo, the clinical improvement using this therapeutic exceeds the standard of care. Instead of a pharmaceutical product, this composition is an orally administered food product with the same safety profile as eggs and milk.
Patent WO-2020077290-A1 (WO)
Inventor: MOROZ EKATERINA
IPC: G01N21/64
Filed: 2019-10-11
Abstract: Provided are methods, compositions, and kits for selectively analyzing a sample for viable cells and nonviable cells. For example, the method may include dyeing viable cells and/or nonviable with a membrane-permeable fluorescent dye, and dyeing nonviable cells with a membrane-impermeable fluorescent quenching dye. The method may include illuminating to cause fluorescent emission from the membrane-permeable fluorescent dye in the viable cells and the membrane-impermeable fluorescent quenching dye in the non-viable cells. The method may include quenching at least a portion of fluorescence of the membrane-permeable fluorescent dye in the nonviable cells by the membrane-impermeable fluorescent quenching dye. The method may include selectively analyzing the sample for the viable and nonviable cells.
Patent WO-2021015806-A1 (WO)
Title: Method for fracturing a subterranean formation with a foamed system
Inventor: AL-TAQ ALI ABDULLAH
IPC: C09K8/68
Filed: 2019-10-17
Abstract: A method for treating a subterranean formation with a foamed system is disclosed. The method includes introducing a fracturing fluid into the formation. The fracturing fluid includes a first solution and a second solution. The first solution includes an ammonium containing compound. The second solution includes a nitrite containing compound. One or both of the solutions further include a foaming agent. The solutions are mixed within the formation to generate a nitrogen gas. The method further includes, allowing the compounds to generate nitrogen in the presence of the foaming agent to form a foam and generate the foamed system within the formation. Generation of the foamed system produces sufficient pressure from volumetric expansion to generate fractures in the formation. The fractures are held open with a proppant provided with the fracturing fluid to create a conductive path for production of fluids from the formation to the wellbore.
Patent WO-2020082044-A1 (WO)
Title: Mycelium growth bed with perforation layer and related method for creating a uniform sheet of mycelium from a solid-state medium
Inventor: ROSS PHILIP
IPC: A01G18/62
Filed: 2019-10-18
Abstract: A mycelium growth bed for growing a solid substrate-bound mycelium through which the mycelium composite is easily and readily removed. This is achieved through the use of a perforation layer embedded between the mycelium substrate and the mycelium composite so as to create a uniform structural weakness and thereby enhancing harvesting abilities of the ex-substrate mycelium via a greatly reduced and uniform tear strength. The perforation layer, through which the mycelium grows, allows for the gated and controlled extrusion of a matrix of colonial cells that may be easily and uniformly delaminated from the underlying mycelium substrate.
Patent WO-2020101888-A1 (WO)
Title: System and method to infer investigation steps for security alerts using crowd sourcing
Inventor: PATRICH DOTAN
IPC: G06F21/00
Filed: 2019-10-29
Abstract: Techniques are provided to dynamically generate response actions that may be used to investigate and respond to a security alert. Different prediction models are initially trained using a corpus of training data. This training data is obtained by identifying previous security alerts and then grouping together alert clusters. An analysis is performed to identify which steps were used to respond to the alerts in each group. These steps are fed into a prediction model to train the model. After multiple models are trained and after a new security alert is received, one model is selected to operate on the new alert, where the model is selected because it is identified as being most compatible with the new alert. When the selected model is applied to the new alert, the model generates a set of recommended steps that may be followed to investigate and/or respond to the new alert.
Patent WO-2020092894-A1 (WO)
Inventor: FROMME ERIC
IPC: A61K31/53
Filed: 2019-11-01
Abstract: La présente invention concerne des formes solides comprenant du 2-méthyl-1-[(4-[6-(trifluorométhyl)pyridin-2-yl]-6-{[2-(trifluorométhyl)pyridin-4-yl]amino-1,3,5-triazin-2-yl)amino]propan-2-ol, des compositions comprenant les formes solides, des procédés de préparation des formes solides et des méthodes d'utilisation des formes solides.
Patent WO-2020097217-A1 (WO)
Title: Systems and Methods for Training an Autoencoder Neural Network Using Sparse Data
Inventor: PANDARINATH CHETHAN
IPC: G06N3/08
Filed: 2019-11-06
Abstract: Methods and systems are provided to prevent pathological overfitting in training autoencoder networks, by forcing the network to only model structure that is shared between different data variables and to enable an automatic search of hyperparameters in training autoencoder networks, resulting in automated discovery of optimally-trained models. The method may include training a neural network. The training may include applying a first binary mask to the set of training data to determine the training input data. The training may include processing the training input data by the neural network to produce network output data. The training may include determining one or more updates of the parameters based on a comparison of at least a portion of the network output data and a corresponding portion of the training data. The portion of the network output data and the corresponding portion of the training input data being inverts.
Patent WO-2020102557-A1 (WO)
Title: Systems and methods for end-to-end article management
Inventor: PAGE GRAHAM
IPC: B23K26/00
Filed: 2019-11-14
Abstract: Systems and methods are described for managing articles. The systems and methods described herein may comprise an example method for manufacturing an article. The systems and methods provides an end-to-end manufacturing value chain as a closed system and feedback loop.
Patent WO-2020106953-A1 (WO)
Inventor: PRIES HENNING
IPC: E05B39/04
Filed: 2019-11-21
Abstract: A security seal identification that may be matched with an identification of a utility measuring meter. This matching may be done, for instance, by a code which is imprinted on the seal and then matched to a meter number in a database, or by a code such as an encryption of the number assigned to the meter. An encryption may be read by an app on a smartphone or checked offline to determine whether the seal belongs to the meter or if it was altered or changed. A mismatch of numbers or symbols may generally indicate a change or manipulation and warrant an investigation.
Patent WO-2020123615-A1 (WO)
Inventor: STEWART SCOTT J
IPC: A47J37/06
Filed: 2019-12-11
Abstract: Un système de cuisson pour cuire des aliments comprend un boîtier ayant un intérieur creux, un couvercle mobile par rapport au boîtier, et au moins un élément chauffant associé à un boîtier et au couvercle. Le système de cuisson peut fonctionner dans une pluralité de modes comprenant un mode de cuisson par conduction et un mode de cuisson par rayonnement thermique. Dans le mode de cuisson par conduction, le système de cuisson peut fonctionner comme un cuiseur conducteur et dans le mode de cuisson par rayonnement thermique, le système de cuisson peut fonctionner comme un cuiseur à rayonnement.
Patent WO-2020123696-A1 (WO)
Title: Fourniture d'informations de soins de santé personnalisés et de recommandations de traitement
Inventor: SAID MAYA
IPC: G16H50/30
Filed: 2019-12-11
Abstract: Divers modes de réalisation de la présente invention concernent des mécanismes pour mettre en oeuvre une plateforme intégrée qui fournit des informations de soins de santé personnalisés et des recommandations de traitement pour des patients et des soignants. Les données de patients récupérées sont utilisées comme entrée dans un algorithme de personnalisation qui génère des recommandations et des options de traitement personnalisées spécifiques pour le patient. Des recommandations et des options de traitement sont affichées pour le patient en langage ordinaire pour faciliter une compréhension correcte. La traduction d'options de traitement en langage ordinaire peut être effectuée automatiquement.
Patent WO-2020123890-A1 (WO)
Title: Introducteur en polymère destiné à être utilisé avec une sonde d'ablation rf et ensemble sonde d'ablation rf associé
Inventor: WANG RUOYA
IPC: A61B18/14
Filed: 2019-12-13
Abstract: La présente invention concerne un introducteur médical destiné à être utilisé dans la localisation d'une sonde de distribution d'énergie, telle qu'une sonde d'ablation RF, à un emplacement cible dans un tissu. L'introducteur comprend un moyeu proximal et une canule allongée ayant une extrémité distale et une extrémité proximale, l'extrémité proximale étant reliée au moyeu. La canule est entièrement constituée d'un matériau polymère électriquement isolant et comprend une pointe distale effilée. L'invention concerne également un système de sonde d'ablation RF qui comprend un ensemble sonde d'ablation RF, un stylet et l'introducteur.
Patent WO-2020146645-A1 (WO)
Inventor: YE CHUNXUAN
IPC: H04W4/46
Filed: 2020-01-09
Abstract: La présente invention concerne des procédés, des dispositifs, et des systèmes pour l'attribution de ressources. En particulier, une unité d'émission/réception sans fil (WTRU) peut mesurer un niveau de puissance de réception de signal de référence (RSRP) et une valeur d'indicateur d'intensité de signal reçu (RSSI) d'une ou plusieurs ressources dans chacun d'une pluralité de motifs. La WTRU peut exclure de la sélection chaque motif pour lequel au moins une ressource dans le motif est réservée par une autre WTRU et a une RSRP supérieure à un seuil. Si un ou plusieurs de la pluralité de motifs n'est pas exclu, la WTRU peut sélectionner un motif ayant une valeur RSSI de motif la plus faible et une ou plusieurs ressources satisfaisant une exigence de qualité de service (QoS) de données de la WTRU. La WTRU peut ensuite transmettre les données de la WTRU à l'aide du motif sélectionné.