baber/WOPTO huggingface dataset:
Patent CA-2543939-A1 (CA)
Inventor: LEVIN ANDREW E
IPC: C12Q1/26
Filed: 2004-10-22
Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-.beta.-D-glucan in a sample.
Patent CA-2547103-A1 (CA)
Title: Carbon dioxide blown low density, flexible microcellular polyurethane elastomers
Inventor: YOUNES USAMA E
IPC: C08J9/08
Filed: 2006-05-16
Abstract: Microcellular polyurethane flexible foams having densities no greater than 0.3 g/cc which are suitable for use as lightweight shoe sole components are produced with carbon dioxide in an amount such that the polyurethane-forming mixture has a free rise density of from about 0.03 to about 0.3 g/cc. At least a portion of that carbon dioxide is dissolved as a gas into one or both of the reaction components. The amount of dissolved carbon dioxide must be such that the froth density of the isocyanate and/or isocyanate-reactive component(s) in which the carbon dioxide is dissolved will be from about 0.1 to about 0.8 g/cc. Additional carbon dioxide may be formed by the reaction of water and isocyanate during the polyurethane-forming reaction but the total amount of CO2 present should be controlled to ensure that the polyurethane-forming mixture has a free rise density of from about 0.03 to 0.3g/cc. Use of a preferred isocyanate-reactive component in which a specified ratio of diol to triol is satisfied makes it possible to use more water than had been expected. Use of a preferred prepolymer makes it possible to produce microcellular polyurethanes having good physical properties solely with a diol. The product microcellular foams possess a uniform cell structure and enhanced physical properties as compared to all water-blown foams of the same basic formulation and density. The hardness of the foams is more suitable for shoe sole, particularly midsole applications, than that of the water-blown foams, despite the lower urea hard segment content of the CO2 blown foams.
Patent CA-2548426-A1 (CA)
Title: Substituted piperazines
Inventor: AGGEN JAMES B
IPC: A61K31/506
Filed: 2004-12-08
Abstract: Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
Patent CA-2552002-A1 (CA)
Title: Azabenzofuran substituted thioureas as inhibitors of viral replication
Inventor: CHEN DAWEI
IPC: A61K38/21
Filed: 2005-01-05
Abstract: The present invention provides compounds of Formula: (1), wherein the variables Ar, A1, A2, A3, A4, R5, R6, R7, V, W, X, and Y are defined herein.  Certain compounds of Formula (1) described herein possess potent antiviral activity. The invention also provides compounds of Formula (1) that are potent and/ or selective inhibitors of Hepatitis C virus replication. The invention also provides pharmaceutical compositions containing one or more compounds of Formula (1), or a salt, solvate, or acylated prodrug of such compounds, and one or more pharmaceutically acceptable carriers, excipients, or diluents. The invention further comprises methods of treating patients suffering from certain infectious diseases by administering to such patients an amount of a compound of Formula (1) effective to reduce signs or symptoms of the disease.  These infectious diseases include viral infections, particularly HCV  infections. The invention is particularly includes methods of treating human patients suffering from an infectious disease, but also encompasses methods of treating other animals, including livestock and domesticated companion animals, suffering from an infectious disease. Methods of treatment include administering a compound of Formula (1) as a single active agent or administering a compound of Formula (1) in combination with on or more other therapeutic agent.
Patent CA-2553436-A1 (CA)
Inventor: PINCUS MATTHEW R
IPC: A61K47/48
Filed: 2004-12-22
Abstract: L'invention concerne des peptides correspondant à la totalité ou à une partie de résidus d'acide aminé 12-26 de la protéine p53. Ces peptides sont létaux pour des cellules transformées et malignes, lorsqu'ils sont fusionnés à une séquence de tête de pénétration membranaire. Pour réduire la protéolyse d'un tel peptide, au moins un acide aminé D peut être substitué par des acides aminés L correspondants de la partie p53 et/ou de la tête de pénétration membranaire du peptide. En outre, une liaison pseudopepditique ou une liaison pseudopeptidique rétro/inverso peut être substituée par au moins une liaison peptidique dans la séquence p53 ou dans la séquence de tête de pénétration membranaire, ou dans les deux, de sorte à rendre le peptide susmentionné moins prédisposé à une protéolyse. En outre, à la fois la séquence de tête de pénétration membranaire et la partie p53 du peptide susmentionné peuvent comprendre des isomères rétro/inverso et des isomères rétro/inverso partiellement modifiés. De tels isomères sont moins sensibles à une protéolyse, et présentent par conséquent des demi-vies prolongées. Les peptides susmentionnés sont utiles pour traiter une maladie néoplastique chez un animal, de préférence un humain. L'invention concerne des compositions pharmaceutiques comprenant les peptides susmentionnés mélangés à un excipient pharmaceutiquement acceptable. L'invention concerne des méthodes de traitement d'une maladie néoplastique chez un patient. Ces méthodes consistent à administrer un peptide susmentionné fusionné à son extrémité carboxyterminale à une séquence de tête de pénétration membranaire. L'invention concerne également des méthodes pour évaluer le niveau d'efficacité d'un peptide susmentionné pour tuer in vitro des cellules néoplastiques ou des cellules transformées ou des cellules malignes.
Patent CA-2553722-A1 (CA)
Title: Pressure loaded pilot valve system and method for a regulator without atmospheric bleed
Inventor: LAW STEPHANIE MARIE
IPC: G05D16/20
Filed: 2004-12-15
Abstract: A pressure loaded pilot valve system and method for a regulator valve is provided. The system includes a regulator valve connecting an inlet line to an outlet line, a servo control valve assembly, and a pilot valve assembly. A  supply line is connected to the servo control valve, and a pilot loading pressure line connects the servo control valve to the pilot valve assembly. An exhaust line connects the servo control valve to the outlet line, thereby avoiding waste, pollution, etc. associated with bleeding excess pilot pressure to the atmosphere.
Patent CA-2554768-A1 (CA)
Title: System and method for automatically updating business information reports
Inventor: STEWART JOHN R
IPC: G06Q10/00
Filed: 2005-01-27
Abstract: The invention includes methods, systems, and computer-readable media that provide an automatically updated business information report to a customer by performing steps including updating daily a database of business information with newly available business information that is more current than that present in the database, generating a business information report in dependence on data retrieved from the database, storing the generated business information report for customer access, updating the business information report with data retrieved from the database that is more current than that presently contained in the business information report; the updating occurring upon each access of the business information report by the customer; and storing the automatically ~updated business information report for further customer access.
Patent CA-2555141-A1 (CA)
Title: Devices and methods for inserting a spinal fixation element
Inventor: LOPEZ ERASMO
IPC: A61B17/88
Filed: 2005-02-03
Abstract: A method for introducing a spinal fixation element between two bone anchors includes engaging a spinal fixation element to a shaft of an instrument, positioning the shaft of the instrument through a sidewall opening of a first percutaneous access device connected to a first bone anchor and through a side wall opening of a second percutaneous access device connected to a second bone anchor, the spinal fixation element extending in an orientation substantially parallel to the longitudinal axis of at least one of the first percutaneous access device and the second percutaneous access device, and pivoting the instrument to change the orientation of the spinal fixation element and position the spinal fixation element in proximity to the first bone anchor and in proximity to the second bone anchor.
Patent CA-2555807-A1 (CA)
Inventor: BRYENTON ALAN
IPC: A61B5/02
Filed: 2005-02-09
Abstract: The present invention relates to an apparatus and method for the non-invasive analysis of physiological attributes, such as heart rate, blood pressure, cardiac output, respiratory response, body composition, and blood chemistry analytes including glucose, lactate, hemoglobin, and oxygen saturation. Using a combination of multi-functioning disparate sensors, such as optical and electrical, improvements are made over existing physiological measurement devices and techniques. The special configuration of one or more multi-functional sensors is used to non-invasively measure multi-wavelength optical plus one or more of ECG, Bio-impedance, and RF-impedance spectroscopic data. This information is used to develop self-consistent, non-linear algorithm in order to derive the physiological attributes while compensating for various forms of interfering effects including motion artifacts, sensor attachment variability, device component variability, subject physical and physiology variability, and various interfering physiological attributes.
Patent CA-2555942-A1 (CA)
Title: System and method for towing subsea vertical antenna
Inventor: LU XINYOU
IPC: H01Q1/12
Filed: 2004-12-06
Abstract: System and method for maintaining vertical alignment of the electrodes of a dipole antenna as it is towed submerged in water.
Patent CA-2557277-A1 (CA)
Title: A production line and a method of forming profiles
Inventor: INGVARSSON LARS
IPC: B21D5/08
Filed: 2005-02-23
Abstract: Profiles (50) are formed in a production line with a cross-section that varies along their length from a plane metal strip (10) that is unwound from a coil (9), whereby edge cutters (14) and a number of roll-forming units (17-24) are used where not only the edge cutters but also the roll-forming units can be displaced individually sideways relative to the strip. The edge cutters (14) and the roll-forming units (17-24) are individually controlled such that they follow the lines of extent of the side edges (51, 52) that are cut and the lines of the corners (53-56) that are subsequently formed, and the forming of one corner with a number of roll-forming units is started only after the forming of a corner that lies more closely to the edge of the strip has been completed. The formed profile is bent in a bending station integrated into the line, which bending station comprises rollers (35-40) that can be controlled to roll sections of the profile (50) to become thinner such that the profile is bent or twisted as it is formed.
Patent CA-2558568-A1 (CA)
Inventor: DE LA TORRE MARTA GARCIA
IPC: C07C235/42
Filed: 2005-03-08
Abstract: A compound of the formula (I) wherein the variables X1, X2, R<SUP>1 </SUP>to R<SUP>7 </SUP>including R<SUP>3</SUP>', j, k, p, y, and z, are as defined or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.
Patent CA-2560968-A1 (CA)
Title: Wheeled device for bag-like container and method with regard to the device
Inventor: VAN RHEENEN REMCO
IPC: B62B3/08
Filed: 2005-03-23
Abstract: The present invention relates to a mobile device for a deformable container, comprising: a frame, wheels arranged on the frame for moving the device, fastening means arranged on the frame for fastening the top part of the container, at least one support member for supporting the container, wherein the device comprises tilting means for tilting the support member relative to the frame. The frame preferably comprises engaging means for releasably engaging the support member.
Patent CA-2561282-A1 (CA)
Title: Apparatus and method for equine facial protection
Inventor: DYCK PAUL
IPC: A01K29/00
Filed: 2006-09-26
Abstract: A full frontal facial safeguard or protective facial shield apparatus protects the facial area of a horse against unwanted and unnecessary injuries, wounds and scaring caused by facial cuts, scratches, scrapes, bumps, and bruises.  The apparatus comprises of a protective, padded facial shield spanning from a bridge area to a poll area of a horse while cheeks and the eye area of the horse remain unobstructed. The full frontal facial safeguard can be produced in various sizes to fit most breeds and sizes of horses.
Patent CA-2561799-A1 (CA)
Title: Drive unit for a mowing sickle
Inventor: SCHUMACHER GUSTAV
IPC: F16H37/02
Filed: 2006-10-02
Abstract: Drive unit for oscillatingly driven mowing sickles comprising a first transmission unit 1, having a first housing 5, which forms a first axis 6, having a rotor 7, which is rotationally supported in the first housing 5 around the first axis 6, having a first internal gear wheel 10, fixed in the first housing 5 and provided with an internal toothing, having a toothed pinion 14, which is rotationally supported in the rotor 7 around a second axis 12, wherein the second axis 12 is radially off-set to the first axis 6 and wherein the toothed pinion 14 forms the output element of the drive unit and meshes with the first internal gear wheel 10, a second transmission unit 2, which output 34 is non-rotationally connected to the rotor 7 of the first transmission unit 1 and which is formed as a step-down gear, a motor 4, having an output shaft 45, which rotationally drives the second transmission unit 2, which rotational speed N1 is reduced by the second transmission unit 2 formed as a step-down gear, to the rotational driving speed N2 of the first transmission unit 1.
Patent CA-2563079-A1 (CA)
Title: Facet joint prosthesis measurement and implant tools
Inventor: BROMAN RICHARD J
IPC: A61F2/46
Filed: 2005-04-08
Abstract: The present invention provides tools and methods designed to aid in the placement of facet joint prostheses at virtually all-spinal levels. One aspect of the present invention is a measurement tool (400) for installing a cephalad facet joint prosthesis including a fixation measurement element (402) and a support arm element (401). This measurement tool assists in the selection and/or configuration of a cephalad facet joint prosthesis for implantation in a patient. Another aspect is a measurement tool (700) for installing a caudal facet joint prosthesis including a stem element (701) and a trial caudal bearing surface element (702). This measurement tool assists in the selection and/or configuration of a caudal facet joint prosthesis for implantation in a patient. Yet another aspect is a measurement tool holder (800) including a measurement surface (801) connected to a holder element (802). These tool holder assists in determining the measurements obtained with the caudal facet joint prosthesis measurement tool.
Patent CA-2563129-A1 (CA)
Title: Vacuum infusion port apparatus and method of use
Inventor: VOEGELI RONALD C
IPC: B29C70/44
Filed: 2006-10-11
Abstract: Vacuum infusion molding is performed by inserting a flexible bag over dry goods disposed in an open mold space of a rigid mold, and over a plurality of bases disposed on the dry goods, attaching a periphery of the bag to the mold, making a slit in the bag over a through-passage of one of the bases, pushing a fitting through the slit and into the one base to communicate the mold space with an area outside of the mold space, and applying a vacuum to the mold space through that fitting to draw the bag tightly against a surface of the dry goods. Prior to the making of the slit, the bag is affixed to the one base without tearing the bag. During the subsequent application of the vacuum, the bag is unsecured relative to the other bases to be able to move freely relative to those other bases under the action of the vacuum.
Patent CA-2563467-A1 (CA)
Inventor: DIDONATO SANTE
IPC: B29B7/76
Filed: 2005-04-06
Abstract: La présente invention se rapporte à un ensemble pistolet de pulvérisation d'uréthane possédant un corps principal doté d'un alésage et d'une chambre de mélange. Une bobine oblongue est montée coulissante, de manière longitudinale, dans l'alésage du corps principal et est susceptible de se déplacer entre une position d'extension et une position de retrait sous l'effet d'un actionneur. Un premier et un second orifice d'entrée sont formés dans le corps principal et un premier et un second orifice de sortie sont également formés dans ce corps principal. Un premier passage pour fluide s'étendant axialement est formé dans la bobine et ce premier passage pour fluide relie de manière fluidique le premier orifice d'entrée au premier orifice de sortie tandis que la bobine se trouve soit dans la position de retrait soit dans la position d'extension, et relie de manière fluidique le premier orifice d'entrée à la chambre de mélange lorsque la bobine se trouve dans l'autre position de retrait ou d'extension. Un second passage s'étendant axialement est formé dans la bobine et ce second passage pour fluide relie de manière fluidique le second orifice d'entrée au second orifice de sortie lorsque la bobine se trouve soit dans son état de retrait soit dans son état d'extension, et relie de manière fluidique le second orifice d'entrée à la chambre de mélange lorsque la bobine se trouve dans l'autre position de retrait ou d'extension. Un orifice de distribution formé dans le corps principal est ouvert sur la chambre de mélange pour distribuer le mélange fluide à l'intérieur de cette chambre de mélange.
Patent CA-2564926-A1 (CA)
Title: A system for determining medical resource utilization characteristics
Inventor: MONITZER ARNOLD
IPC: G06F19/00
Filed: 2005-03-02
Abstract: A system is interfaced with multiple different financial, clinical and inventory information systems that provide information for on-line analytical processing to provide resource usage characteristics. A system for determining characteristics of resource usage, includes an acquisition processor for automatically acquiring data representing information. The acquired information includes revenue received for a particular usage of a particular resource by a particular patient, operating cost of maintaining the resource, and an acquisition cost of the resource. A data analyzer processes the acquired information to determine a profit or loss attributable to the resource. A communication processor communicates a message to a remote unit indicating the profit or loss in response to user command
Patent CA-2566589-A1 (CA)
Inventor: METCALF STEPHEN
IPC: G01B11/08
Filed: 2005-06-01
Abstract: Method of detecting a potentially void inhaler can valve (30), which valve (30) is attached to a can (10) by a ferrule crimp (80), comprising the steps:  placing the can (10) in a can jig (220) that is arranged to retain the can (10) at a predetermined measurement height with respect to a diameter measuring means (230),measuring the diameter of the ferrule crimp (80) at the predetermined height, and comparing the measured crimp diameter with a predefined interval of acceptance, and if the measured diameter is outside a predefined interval classifying the inhaler can valve (30) as potentially void. There is also provided a crimp diameter measuring device (200) comprising: a base (210), a diameter measuring means (230) supported by the base (210), and a can jig (220) supported by the base (210), the can jig (220) being arranged to retain a can (10) placed therein at a predetermined measurement height with respect to a diameter measuring means (230).
Patent CA-2570585-A1 (CA)
Inventor: HALABISKY DONALD D
IPC: B32B23/02
Filed: 2006-12-07
Abstract: An insulating paperboard contains at least one layer of cellulose fibers. The one layer is at least partially composed of crosslinked fibers and processed cellulosic fibers. The paperboard provides sufficient insulation to provide a .DELTA.T across the paperboard of at least 3.6°C at 0.5 mm. A hot cup may be produced from the insulating paperboard.
Patent CA-2570591-A1 (CA)
Inventor: LEE VING
IPC: C07F5/04
Filed: 2005-06-14
Abstract: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
Patent CA-2571831-A1 (CA)
Inventor: RANAHAN DOUG
IPC: H04J14/02
Filed: 2005-07-15
Abstract: Modular WSS (wavelength selective switch) designs are provided that allow a WSS to be built out for a first set of wavelengths, with the capacity for later expansion to handle a second set of wavelengths with minimal impact on the operation of the system for the first set of wavelengths. An optical signal separator separates each incoming signal into the two bands, and at each output, the bands are then re-combined. In between, wavelength selective switching is performed separately for each of the two bands, or initially only for one of the bands, with later upgradability to switch the second band.
Patent CA-2575656-A1 (CA)
Title: Method of processing volatile organic compound by using gas turbine and processing system of volatile organic compound
Inventor: UJI SHIGEKAZU
IPC: B01D53/96
Filed: 2007-01-25
Abstract: A processing system according to the present invention is provided including:  an adsorption apparatus in which a volatile organic compound contained in gas to be treated is adsorbed in a predetermined absorption agent, and said volatile organic compound thus adsorbed is desorbed using steam under a pressurized environment and mixed with the steam; a gas turbine having a combustor in which the steam mixed with the volatile organic compound is burnt; and a steam generating apparatus which generates steam through the use of the heat of the combustion gas discharged from the gas turbine; and wherein, by supplying compressed air discharged from the gas turbine to the adsorption apparatus, condensation of the steam in the adsorption apparatus at the time of the desorption of the volatile organic compound is suppressed.
Patent CA-2576726-A1 (CA)
Inventor: ESCARGUEL CLAUDE
IPC: G01N33/543
Filed: 2005-07-29
Abstract: The present invention concerns a method for determining vaccine status by quantifying type-IgG serum antibodies of a plurality of pathogenic agents, characterized in that the steps are conducted of: 1-contacting one same said serum sample to be tested with one same solid substrate on which a plurality of said vaccine antigens is fixed corresponding to a plurality of vaccine antigens of different pathogenic agents, at different areas of the substrate, in the presence of at least one detection substance reacting by complexing with said IgG-type specific antibodies and not reacting with said vaccine antigens, and 2-the concentration of said IgG-type specific antibodies is determined.