baber/WOPTO huggingface dataset:
Patent CA-2592993-A1 (CA)
Title: Method for detecting methylation in genes and method for examining neoplasm through detecting methylation in genes
Inventor: TANAKA NORIAKI
IPC: C12Q1/68
Filed: 2005-12-09
Abstract: It is intended to provide a method of conveniently and economically detecting the methylation of a gene contained in a biological sample. It is also intended to provide an accurate and sensitive examination method to be used in the case of examining a neoplasm by using the method of detecting gene methylation. In examining the methylation of a gene, a polysaccharide is added to a biological sample before treating it with a bisulfite. Thus, the subsequent bisulfite treatment can be conducted while requiring neither the addition of a protein-denaturing agent nor the purification of DNA. Thus methylated cytosine without uracil-modification can be detected. Moreover, a neoplasm can be examined at an elevated accuracy by detecting the methylation of genes of multiple species contained in a biological sample and calculating the sum thereof.
Patent CA-2593681-A1 (CA)
Title: Patches for locating infusion sites
Inventor: JACOBS MICHAEL W
IPC: A61B17/34
Filed: 1998-05-15
Abstract: This invention relates to an apparatus and method for infusing fluids to and aspirating tissue from an intraosseous site. The apparatus is comprised of an infusion tube coupled to an introducer with a release mechanism that removes the infusion tube once it has penetrated the bone a predetermined depth. As the introducer is withdrawn, the infusion tube remains in the bone. The ball release mechanism and other aspects of the apparatus can be modified to yield different penetration depths. The present invention also relates to a method and apparatus for locating the site of infusion and for relieving strain and stress on the infusion site. The template patch uses a key anatomical feature of the bone as a reference point to a target zone for infusion that is located a predetermined distance away from the feature. The template patch has a tube clamp and a covering that protect the infusion site from external forces.
Patent CA-2595263-A1 (CA)
Title: Ischemic biomarkers and their use to predict adverse neurological events from surgery
Inventor: DAMBINOVA SVETLANA A
IPC: G01N33/53
Filed: 2006-01-24
Abstract: Methods are provided for predicting the occurrence of adverse neurological events from surgery. Such adverse events include, for example, stroke, delirium and transient ischemic attach (TIA). The methods are based on the discovery that levels of circulating cerebral NMDA receptor peptides and antibodies can be used to identify patients who are likely to suffer from an adverse neurological event. Also provided are diagnostic procedures for practicing the predictve methods of the current invention, and interventional strategies for reducing the risk of adverse neurological events from surgery (Figure 1).
Patent CA-2597075-A1 (CA)
Inventor: PETERSON MATTHEW
IPC: G06Q40/00
Filed: 2006-02-08
Abstract: A system and method for processing prepaid financial transactions. The system and method describe the utilization of one or more remote terminals (104) that are adapted to acquire transaction information from a user and transmit a first signal indicative of the transaction information. The remote terminal is further adapted to receive a second signal indicative of authorizing information that is delivered to the user. In addition, an authorizing host (108) is adapted to receive the first signal transmitted by the one or more remote terminals. In one aspect, the authorizing host routes the first signal including the transaction information to an exchange host (156) for approval of the financial transaction, and the exchange host (156) transmits the second signal including the authorizing information to the remote terminal (104) via the authorizing host (108).
Patent CA-2598115-A1 (CA)
Title: Graduated train braking
Inventor: KELLNER STEVEN ANDREW
IPC: B60T13/66
Filed: 2005-09-23
Abstract: A system (10) and method for automatically controlling braking of a train (38). The method includes applying a first degree of braking to the train during a first period of time, and then applying a second degree of braking to the train during a second time period following the first time period so that the train is slowed in a manner effective to limit a peak deceleration rate experienced by the train. The system includes a sensor (36) providing a signal indicative of an operating condition of a locomotive of the train requiring braking of the train, a memory (22) storing a braking schedule, and a processor (18) comprising logic executable for accessing the braking schedule stored in the memory responsive to the signal to automatically control braking of the locomotive according to the schedule.
Patent CA-2599154-A1 (CA)
Title: Method and device for the assessment of bowel function
Inventor: HOPP MICHAEL
IPC: G06F19/00
Filed: 2006-02-28
Abstract: The present invention provides a method for assessing bowel function in a patient, comprising providing the patient with a numeric analog scale for at least one parameter which is a measure of bowel function; causing the patient to indicate on the numeric analog scale the amount and/or intensity of the parameter being experienced; and observing the amount and/or intensity of the at least one parameter indicated on the numeric analog scale in order to assess bowel function. Further, the present invention provides a device for assessing bowel function in a patient, the device comprising a display unit for providing a numeric analog scale for at least one parameter which is associated with bowel function of a patient; a receiving unit adapted to receive an amount and/or intensity of the at least one parameter indicated by the patient on the numeric analog scale; and an interface unit adapted to provide the amount and/or intensity of the at least one parameter indicated on the numeric analog scale in order to assess bowel function.
Patent CA-2602979-A1 (CA)
Title: Improved mattress
Inventor: BALONICK ARNOLD
IPC: A47C27/18
Filed: 2006-03-28
Abstract: Air mattresses primarily intended for hospitals, long-term care facilities and in-home use are described. The mattress includes multiple foam layers and an air sector having multiple resilient foam filled air cylinders. The air cylinders at different locations are filled with foam having different density (firmness); some are filled with multiple layers of foam. Each air cylinder has an air inlet connected to the atmosphere by an inlet valve and an air outlet. The air outlets are either connected to one or more restricted internal check outlet valves in a non-powered air mattress, or connected to a pump via hose connectors in a powered air mattress. The restricted outflow of air from the cylinders in a non-powered air mattress allows the patient to slowly settle into the supportive foam layers for optimal interface pressure distribution. The air cylinders re-inflate when the patient adjusts position or is vacated from the surface.
Patent CA-2603432-A1 (CA)
Title: Rendering 3d computer graphics using 2d computer graphics capabilities
Inventor: ELBER GERSHON
IPC: G06T15/00
Filed: 2006-04-04
Abstract: Method for generating and displaying 3D graphic images on the display of a terminal device using 2D graphic environments, where every possible scene is modeled by one or more objects that can be represented by polygons using a suitable modeling method. The geometry of the polygons that correspond to each object is projected for any desired orientation of the objects, onto the plane of the display. For each object, curves connecting the projections of the vertices of its corresponding mesh of polygons in all different orientations of that object and consisting of a plurality of discrete points, is created, such that every point on each curve is stored according to its (x,y) position on the plane, and such that the resolution of each curve is determined according to the number of points. A visibility analysis is performed for every mesh that corresponds to a specific orientation, thereby determining the distance of the points from the viewer. Hidden polygons and/or edges or portions thereof are deleted and the geometry for all orientations is optimally encoded. Then 3D graphic images are displayed in the 2D environments by using the encoded geometry for reconstructing a portion of, or all, the remaining polygons and filling the remaining polygons according to predefined rules.
Patent CA-2606580-A1 (CA)
Title: Improved inlet plenum for gas turbine engine
Inventor: MEHRING CARSTEN
IPC: F02C7/05
Filed: 2007-10-12
Abstract: An inlet plenum for coupling airflow from a radial airflow inlet to an axial compressor inlet for a compressor comprises a perforated inlet (PI) baffle that comprises a generally cylindrical baffle that circumscribes the compressor inlet and a plurality of apertures, each aperture perforating the baffle to pass the airflow from the radial airflow inlet to the compressor inlet and a plurality of stagnation vanes, each stagnation vane comprising a generally arc-shaped vane that extends proximate the PI baffle to establish an approximation of stagnant flow around the entire PI baffle to reduce flow distortion of the airflow between the radial airflow inlet and the axial compressor inlet.
Patent CA-2609283-A1 (CA)
Title: Real-time precision ray tracing
Inventor: KELLER ALEXANDER
IPC: G06T15/50
Filed: 2006-06-23
Abstract: Ray tracing and efficient construction of acceleration data structures required for fast ray-tracing. A computer graphics system generates, for each pixel in an image, a pixel value that is representative of a point in a scene as reported on an image plane of a simulated camera. The computer graphics system is configured to generate the pixel value for an image using a selected ray-tracing methodology. The selected ray-tracing methodology includes the use of a ray tree that includes at least one ray shot from the pixel into a scene along a selected direction. The ray-tracing methodology further includes calculating the intersections of rays and surfaces in the scene. An axis-aligned bounding box is defined that contains, for a given ray, the point of intersection of the ray and the surface nearest the origin of the ray. The bounding box is iteratively refined until a predetermined termination criterion has been met.
Patent CA-2609464-A1 (CA)
Inventor: KAY JAMES
IPC: H04L12/58
Filed: 2006-06-22
Abstract: Embodiments of the invention are concerned with filtering emails having data therein identifying a link to a remote processing system, which, when activated, causes the recipient to retrieve data from the remote processing system. Embodiments of the invention provide a method of modifying an electronic message during transmission through a communications network, said electronic message having a source address and a recipient address, the method comprising: interrupting transmission of the electronic message; identifying a link specified within the electronic message; analyzing the electronic message on the basis of at least an attribute intrinsic to the received electronic message so as to classify the received message as either a first type of message or a second, different, type of message; if the received message is classified as the first type of message, modifying the received electronic message so as to replace the link with an alternative network location, said alternative network location corresponding to a remote processing system different to that corresponding to the link; and transmitting the modified electronic message. In comparison to known methods, which either modify the links blindly or which perform analysis of the data to which the link is connected, embodiments of the invention selectively modify the link on the basis of various tests relating to attributes intrinsic to the email. This means that only those emails that present some sort of risk to the recipient are modified, and, because the criteria for performing the modification relate to attributes intrinsic to the emails instead of the content associated with the link, the delivery of emails is not significantly delayed by processes involved in retrieval and analysis of data from third party sites.
Patent CA-2611529-A1 (CA)
Inventor: HAMANN LAWRENCE G
IPC: A61P3/00
Filed: 2006-06-08
Abstract: Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure:(I) or stereoisomers or pharmaceutically acceptable salts thereof, wherein W, L, R3, R3a, R3b and R4 are defined herein.
Patent CA-2612644-A1 (CA)
Title: Modulation of sphingosine kinase signalling
Inventor: VADAS MATHEW ALEXANDER
IPC: C12N9/99
Filed: 2006-06-21
Abstract: The present invention relates generally to a method of modulating cellular activity and to agents for use therein. More particularly, the present invention provides a method of modulating the level of sphingosine kinase functional activity. In a related aspect, the present invention provides a method of modulating sphingosine kinase mediated signalling via modulation of its intracellular level of activity. The present invention still further extends to novel molecules which exhibit the capacity to induce sphingosine kinase activity. The methods and molecules of the present invention are useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by aberrant, unwanted or otherwise inappropriate cellular functional activity and/or aberrant, unwanted or otherwise inappropriate sphingosine kinase mediated signalling. The present invention is further directed to methods for identifying and/or designing agents capable of modulating the level of sphingosine kinase activity.
Patent CA-2612880-A1 (CA)
Inventor: BOGER HENRY W
IPC: F16L55/02
Filed: 2003-03-19
Abstract: A noise reduction device for fluid flow systems comprises an inner section and an outer annular section. The inner section and the outer annular section has apertures on both upstream and downstream sides. The total cross-sectional area of the downstream apertures of the outer section is less than the total cross-sectional area of the downstream apertures of the inner sections. The device also includes a fin downstream of the downstream apertures of the inner section and of the downstream apertures of the outer section and between the inner section and the outer section. The fin facilitates separation between fluid flow from the inner section and fluid flow from the outer section.
Patent CA-2613290-A1 (CA)
Title: Focused microarray and methods of diagnosing chemotherapeutic drug resistance in a cancer cell
Inventor: GEORGES ELIAS
IPC: C40B40/10
Filed: 2006-05-30
Abstract: Disclosed are methods for diagnosing chemotherapeutic drug resistance in a cancer cell sample by detecting an increase in the levels of expression of marker genes in the cancer cell sample as comp Ësd to the levels of expression of the same marker genes in a chemotherapeutic drug-sensitive cancer cell of the same tissue type. Also disclosed is a focused microarray device for diagnosis of chemotherapeutic drag resistance in cancer cells.
Patent CA-2614249-A1 (CA)
Inventor: BERTHOLDT HORST-OTTO
IPC: G21F9/28
Filed: 2006-11-15
Abstract: The invention relates to a method for decontaminating an oxide layer-containing surface of a component or a system of a nuclear facility. According to said method, the oxide layer is treated with a gaseous oxidant.
Patent CA-2614775-A1 (CA)
Title: Compositions from buckwheat for management of diabetes
Inventor: KAWA JULIANNE MARIE
IPC: A23L35/00
Filed: 2006-07-11
Abstract: A buckwheat extract comprising at least myo-inositol, D-chiro-inositol, a fagopyritol, one MAPK-stimulating compound, and one glucose-uptake inhibiting compound. A substantially pure glucose-uptake inhibiting compound selected from a buckwheat extract. A method for providing a glucose-uptake inhibiting extract from buckwheat seed comprising first contacting said buckwheat seed with a non- polar solvent, then contacting said buckwheat seed with a polar aprotic solvent, and then finally contacting said buckwheat seed with a third solvent. The third solvent may be a polar aprotic solvent or a polar protic solvent. The extract produced by contacting buckwheat seed with the third solvent is dried to remove the solvent therefrom. Compositions comprising dried glucose-uptake inhibiting buckwheat extracts and purified compounds therefrom.
Patent CA-2615475-A1 (CA)
Title: Methods of isolating zones in subterranean formations using self-degrading cement compositions
Inventor: SAVERY MARK R
IPC: C09K8/504
Filed: 2006-07-18
Abstract: Methods of isolating particular zones within a subterranean formation utilizing self-degrading cement compositions are provided. An example of a method of the present invention is a method that includes: providing a self-degrading cement composition that includes a degradable material, an acid source, a base source, and a water source; placing the self-degrading cement composition in a zone within a subterranean formation; and allowing the self-degrading cement composition to set to form a solid mass that is capable of isolating the zone from a well bore penetrating the zone or from another zone.
Patent CA-2616384-A1 (CA)
Inventor: KRONENTHAL RICHARD L
IPC: A61M31/00
Filed: 2006-07-25
Abstract: At least three component, body-implantable, absorbable, biocompatible, putty, and non-putty pain-relieving compositions for use in surgery comprising in intimate admixture: an analgesic having local pain-relieving activity for internal relief of pain, a finely powdered bulking material, preferably less than 50 microns, e.g. the metal salts of fatty acid, hydroxyapatite, DBM, polyglycolide, polylactide, polycaprolactones, absorbable glasses, gelatin, collagens, mono, and polysaccharides starches. An organic liquid capable of solubilizing, dispensing or suspending the analgesic, such as esters of monohydric alcohols with aliphatic monocarboxylic acids; C2-C18 monohydric alcohols with polycarboxylic acids; C8-C30 monohydric alcohols; tocopherol and esters thereof with mono or polycarboxylic acids; free carboxylic acids such as oleic, capric, and lauric; dialkyl ethers and ketones; polyhydroxy compounds and esters and ethers thereof; random or block copolymers of ethylene oxide and propylene oxide.
Patent CA-2617239-A1 (CA)
Title: Door leaf
Inventor: BRAMAUER JOHANN
IPC: B61D19/02
Filed: 2006-07-31
Abstract: The invention relates to a door leaf for external sliding doors of railway, high-speed railway, and subway cars, which are composed of a frame (5) and of an at least partially transparent panel (4) of glass or plastic, which is optionally provided in a number of pieces. In order to provide more safety for passengers, the panel (4) is placed on the inside of the frame (5).
Patent CA-2622960-A1 (CA)
Inventor: FRIE JESSICA LESLIE
IPC: A61K31/44
Filed: 2006-09-15
Abstract: A method of treating atherosclerosis and related conditions using compounds of formula I: as well as pharmaceutically acceptable salts and solvates is disclosed. The compounds are useful for treating dyslipidemias, and in particular, reducing serum LDL, VLDL and triglycerides, and raising HDL levels.
Patent CA-2623574-A1 (CA)
Title: Multi-layer, microporous polyethylene membrane, its production method, and battery separator
Inventor: KIKUCHI SHINTARO
IPC: H01M50/489
Filed: 2006-09-27
Abstract: A multi-layer, microporous polyethylene membrane having at least two layers, which comprises (a) a microporous polyethylene resin layer A  comprising high-density polyethylene A having 0.2 or more terminal vinyl groups per 10,000 carbon atoms when measured by infrared spectroscopy, and (b) a microporous polyethylene resin layer B comprising high-density polyethylene B  having less than 0.2 terminal vinyl groups per 10,000 carbon atoms when measured by infrared spectroscopy, has well-balanced permeability, mechanical strength, heat shrinkage resistance, shutdown properties, meltdown properties and oxidation resistance.
Patent CA-2623698-A1 (CA)
Title: Method and system for mining hydrocarbon-containing materials
Inventor: KOBLER MICHAEL HELMUT
IPC: E21F7/00
Filed: 2001-03-12
Abstract: The present invention is directed, inter alia, to devices and methods for excavating valuable materials, particularly soft ores such as oil sands, oil shales, and the like, that use one or more of a number of features, including backfilling for ground support, a small trailing access tunnel, processing of the valuable material in the excavation with the tailings optionally being used as backfill and the valuable material being transported to the surface, a plurality of movable shields for ground support, and/or a movable tail shield to provide interim support to the backfill while additional liner sections are installed and/or formed.
Patent CA-2623767-A1 (CA)
Inventor: FOO ONN FAH
IPC: H01J61/56
Filed: 2008-02-29
Abstract: A fluorescent lamp adapted for effecting stepless dimming with a regular SCR  dimmer, comprising a filter and rectifier circuit (1), a DC high voltage stabilizing circuit (2), a voltage signal detection and frequency control circuit (6), a lamp load (4), a lamp current feedback circuit (5) and a voltage signal sampling circuit (3) thereby changing the power factor and luminous intensity of the lamp in accordance with the variation of the conduction phase angle of the silicon controlled rectifier dimmer. The present invention solves the discontinuity and instability issues in course of dimming operation and is particularly adapted for use in an integrated compact fluorescent lamp.
Patent CA-2624908-A1 (CA)
Inventor: SCOTT SHERRYL LEE LORRAINE
IPC: H04M1/7243
Filed: 2007-05-03
Abstract: Call initiation on a device with potential for a large number of stored telephone numbers is simplified through the use of an integrated field for entry of an ambiguous filter string. As it is not clear, a priori, whether the user is manually specifying, in the integrated field, a telephone number or providing a filter string for filtering contacts, filtering is performed based on at least one filter string. Among the contacts that are part of a filtering result list, a default contact is selected for quick access.
Patent CA-2625058-A1 (CA)
Inventor: MILAT ANTHONY RICHARD
IPC: H03G5/00
Filed: 2006-10-10
Abstract: An audio crossover system and method is disclosed. An audio system includes two driver circuits, one for each of two audio frequency ranges, e.g., high and low frequency ranges. The driver circuits are designed to provide a combined frequency response curve that has a pronounced midrange attenuation dip, in contrast to prior art designs that attempt to provide a flat response over all frequency ranges.
Patent CA-2625440-A1 (CA)
Inventor: KISCHEL ROMAN
IPC: C12N15/13
Filed: 2006-10-10
Abstract: The present invention relates to uses of bispecific antibodies exhibiting cross-species specificity for evaluating the in vivo safety and/or activity and/or pharmacokinetic profile of the same in non-human species and humans.  The present invention moreover relates to methods for evaluating the in vivo safety and/or activity and/or pharmacokinetic profile of said bispecific antibodies exhibiting cross-species specificity. The present invention also relates to methods of measuring the biological activity and/or efficacy of such bispecific antibodies exhibiting cross-species specificity. In addition, the present invention relates to pharmaceutical compositions comprising bispecific single chain antibodies exhibiting cross- species specificity and to methods for the preparation of pharmaceutical compositions comprising said bispecific single chain antibodies exhibiting cross-species specificity for the treatment of diseases.