baber/WOPTO huggingface dataset:
Patent CA-3168485-A1 (CA)
Title: Procedes de sequencage d'arn a cellule unique a resolution spatiale
Inventor: CHOW ERIC
IPC: C12N15/10
Filed: 2021-02-22
Abstract: La présente invention concerne de manière générale la détection spatiale d'un acide nucléique, tel qu'un ADN génomique ou un transcrit d'ARN, dans une cellule comprise dans un échantillon de tissu. La présente invention concerne des procédés de détection et/ou d'analyse d'acides nucléiques, tels que des transcrits de chromatine ou d'ARN, de façon à obtenir des informations spatiales concernant la localisation, la distribution ou l'expression de gènes dans un échantillon de tissu. La présente invention concerne ainsi un procédé de réalisation d'une « transcriptomique spatiale » ou « génomique spatiale » qui permet à l'utilisateur de déterminer simultanément le motif d'expression ou le motif d'emplacement/de distribution des gènes exprimés ou gènes ou loci génomiques présents dans une cellule unique tout en conservant des informations relatives à l'emplacement spatial de la cellule dans l'architecture tissulaire.
Patent CA-3170573-A1 (CA)
Title: Systeme de deplacement autonome
Inventor: KANAI MASAKI
IPC: G05B1/02
Filed: 2021-03-19
Abstract: La présente invention concerne un système de déplacement autonome qui peut supprimer efficacement l'apparition d'ornière. La présente invention concerne également un système de déplacement autonome comprenant un véhicule sans pilote qui se déplace sur un trajet de transport composé de voies opposées, avec lequel il est possible d'empêcher la proximité d'un véhicule venant en sens inverse tout en supprimant l'apparition d'ornière. Un dispositif de commande embarqué 200 comprend : une unité de détermination de quantité de décalage 202 qui, sur la base d'informations de décalage partagées reçues par l'intermédiaire d'un dispositif de communication sans fil 240, détermine une quantité de décalage d'un itinéraire de déplacement 60 sur la base d'informations de carte 251 et génère une trajectoire cible 62 ; et une unité de commande de déplacement autonome 201 qui, sur la base de la trajectoire cible 62 et de la propre position de véhicule d'un corps de véhicule, délivre une instruction de déplacement pour effectuer une commande de déplacement du corps de véhicule de façon à suivre la trajectoire cible 62 à laquelle la quantité de décalage a été ajoutée.
Patent CA-3172849-A1 (CA)
Inventor: KINOSHITA KAZUMASA
IPC: G01N27/62
Filed: 2021-02-03
Abstract: Ce dispositif d'ionisation comprend : une unité de formation d'ions qui ionise, à l'aide d'une décharge par effet couronne, une substance soumise à une analyse; et une unité de transport qui transporte, vers un dispositif de spectroscopie de masse, la substance soumise à une analyse qui a été ionisée. L'unité de formation d'ions et l'unité de transport sont séparées par une électrode qui a une ouverture et qui est une électrode d'une paire d'électrodes qui provoquent la génération d'une décharge par effet couronne.
Patent CA-3174408-A1 (CA)
Title: Systems and methods for augmented-or virtual reality-based decision-making simulation
Inventor: FRED TANNER
IPC: G06T19/00
Filed: 2021-04-28
Abstract: A system for display for an augmented/virtual reality-based decision-making simulation includes a controller configured to receive input from a user, at least one of an augmented reality or a virtual reality device configured to display a simulated environment, a processor, and a memory coupled to the processor. The memory stores one or more computer-readable instructions, which, when executed by the processor, cause the system to: receive input by the user from the controller, indicating a selected scenario; display, on the at least one of the augmented reality or the virtual reality device, the selected scenario; receive input from the user, from the controller, to interact with the selected scenario; monitor one or more parameters associated with the execution of tasks in the selected scenario using the controller; and evaluate the user based on the monitored one or more parameters.
Patent CA-3174839-A1 (CA)
Inventor: OTT TREVOR JOSEPH
IPC: F01N11/00
Filed: 2022-09-19
Abstract: An exhaust aftertreatment system and associated method for purifying an exhaust gas feedstream of a lean-burn or other compression-ignition internal combustion engine is described. An instruction set is executable to determine an engine-out NO2 concentration upstream of an oxidation catalyst and determine a first parameter associated with 02 concentration. A consumption of oxygen in the oxidation catalyst due to oxidation reactions is determined, and a concentration of NO2 generated by the oxidation catalyst is detennined based upon the consumption of oxygen in the oxidation catalyst. A concentration of NO2 downstream of the oxidation catalyst is determined. A  NO2/NOx ratio in the exhaust gas feedstream downstream of the oxidation catalyst is detennined based upon the concentration of NO2 downstream of the oxidation catalyst and the NOx concentration measured by the downstream NOx sensor. The oxidation catalyst is evaluated based upon the NO2/NOx ratio.
Patent CA-3175736-A1 (CA)
Title: Derives de pyridine condenses substitues par des fonctions amide utilises en tant qu'inhibiteurs d'acss2
Inventor: KOETZNER LISA
IPC: C07D471/04
Filed: 2021-03-16
Abstract: La présente invention concerne des dérivés amide substitués. Ces composés sont utiles pour la prévention et/ou le traitement de plusieurs états médicaux comprenant des troubles et des maladies hyperprolifératifs.
Patent CA-3175829-A1 (CA)
Title: Overmold bracket with open mounting surface on bracket
Inventor: KUNTZE CHRISTOPHER J
IPC: B60J5/10
Filed: 2021-04-16
Abstract: A liftgate (10) for a vehicle having at least one overmolding bracket (28) with at least one open mounting surface on the bracket for liftgate hardware attachments. In addition, overmolding the bracket (28) and maintaining at least one hole (26) for tether routing. The liftgate allows the overmolding of the bracket (28) and maintains a lower cost fastener joint that does not require extra components or special components such a compression limiters and rivet nuts or brackets that cannot be overmolded.
Patent CA-3176270-A1 (CA)
Title: Peptide platinum complexes and methods of use thereof
Inventor: DIPAOLA MARIO
IPC: C07K7/08
Filed: 2021-04-22
Abstract: This invention provides novel peptide platinum complexes, pharmaceutical compositions comprising a peptide platinum complex, and methods for treating cancer using a peptide platinum complex. Kits comprising a unit dosage form of a compound or composition of the invention are also provided.
Patent CA-3176377-A1 (CA)
Title: A brewing unit
Inventor: MOLINARO GABRIELE
IPC: A47J31/44
Filed: 2021-06-16
Abstract: Brewing unit (10) for preparing beverages from a powdered product (P) containing at least one ingredient, comprising a support structure (20) having an inner cavity (16), and a dispensing assembly which includes a first assembly part (12) configured as a drawer having a receptacle (13) adapted to receive said powdered product, and a second assembly part (14) mounted to slide vertically within an upper part of said cavity, between a raised position and a lowered position, wherein within said first assembly part there is a filtering element (123) mounted to translate vertically through which there is formed a dispensing duct (124), the filtering element defining a bottom surface of the receptacle (13) and of the brewing chamber, and wherein a brewing head (145) is carried by a lower end of the second assembly part (14), the brewing head defining a top surface of the brewing chamber.
Patent CA-3178773-A1 (CA)
Inventor: MATUSZEWSKI JOHN
IPC: E06B3/663
Filed: 2021-07-15
Abstract: Certain example embodiments relate to an insulating glass (IG) unit. A spacer is interposed between first and second substrates. The spacer helps maintain the substrates in substantially parallel spaced apart relation to one another, and helps define a cavity therebetween. First and second exterior surfaces of the spacer face interior surfaces of the first and second substrates, respectively. Third and fourth exterior surface of the spacer face towards and away from the cavity, respectively. A membrane is provided over at least a part of the fourth exterior surface of the spacer. A pin protrudes through holes in the third and fourth exterior surfaces of the spacer, and through the membrane. The pin is formed from an electrically conducting material. A structural seal for the IG unit is provided external to the spacer and at least partially surrounds a portion of the pin that protrudes through the membrane.
Patent CA-3183151-A1 (CA)
Title: Novel il10 agonists and methods of use thereof
Inventor: DAI JIE
IPC: C07K14/54
Filed: 2021-05-11
Abstract: The present disclosure relates to IL10 agonists with improved anti-tumor therapeutic efficacy.
Patent CA-3183569-A1 (CA)
Inventor: LOPES TORRAO CARLOS FILIPE
IPC: G06F40/35
Filed: 2022-05-30
Abstract: The present invention describes a computer implemented platform with the responsibility of handling complex tasks provided by users via a natural input interface (voice, text, image, among others). This platform design is based on the principle of full scalability, ambient and context awareness and with multi-domain extensible capability. The proposed computer-implemented system ensures the handling of input data provided by users via natural input interfaces, comprising a set of layers arranged in a modular and loosely coupled architecture, wherein the set of layers are adapted to interpret and manage several types of contextual information from the user input data, while permanently improving decisioning and response times, enabling increasingly complex interactions with the user.
Patent CA-3183583-A1 (CA)
Inventor: JEANSON FRANCIS
Filed: 2022-12-07
Abstract: A readout circuit for an electromagnetic inspection system for nondestructive testing of a test object is disclosed. The inspection system includes a plurality of sensors for sensing an electromagnetic response from the test object and generating therefrom a plurality of response signals. The readout circuit can include a plurality of anti-aliasing filters, each configured to receive the response signal from one of the sensors and bandlimit the response signal to produce one of a plurality of bandlimited signals. The readout circuit can also include a time-division multiplexer configured to multiplex the bandlimited signals into a time-division multiplexed (TDM) signal including a sequence of frames outputted at a TDM  frame rate, each frame including a plurality of time slots, each time slot assigned to one of the bandlimited signals, wherein the anti-aliasing filters are configured to operate based on the TDM frame rate to attenuate aliasing artifacts in the TDM signal.
Patent CA-3187222-A1 (CA)
Inventor: SCHUCH RAYMOND
IPC: C12N9/24
Filed: 2013-05-09
Abstract: The present invention provides methods for the prevention, control, disruption and treatment of bacterial biofilms with lysin, particularly lysin having capability to kill Staphlococcal bacteria, including drug resistant Staphylococcus aureus, particularly the lysin Ply Ss2. The invention also provides compositions and methods for use in treatment or modulation of bacterial biofilm(s) and biofilm formation.
Patent CA-3188592-A1 (CA)
Inventor: CWIK TOMASZ
IPC: G05B19/418
Filed: 2021-07-01
Abstract: Disclosed is a method for verifying an application of a foamable material (202) onto a carrier (201) to manufacture an insulated member. The method comprises: - capturing (S1), by at least one image capturing device (120, 460), in image data a surface of the carrier onto which the foamable material is applied, - receiving (S2), by at least one data processing unit (110, 310, 410), input data comprising at least the captured image data and at least one application parameter associated therewith, - processing (S3), by the at least one data processing unit (110, 310, 410), the received input data by performing at least image analysis on the image data and by taking into account the at least one application parameter, and thereby determining an application quality of the applied foamable material.
Patent CA-3192709-A1 (CA)
Title: Integrated air sanitizer and surface disinfector
Inventor: KROSNEY MARK D
IPC: A61L9/20
Filed: 2021-09-14
Abstract: A robotic surface cleaning device is disclosed. The robotic surface cleaning device may be configured to traverse over a floor surface in a room area to disinfect various surface as well as disinfect the air in the room. The robotic surface cleaning device may include a maneuvering base. The robotic surface cleaning device may also include a support tower coupled to the maneuvering base and at least one deployable structure attached to the support tower, wherein the at least one deployable structure is capable of extending and retracting to pass over surfaces in the room area. The at least one deployable structure may include one or more ultraviolet (UV) light source configured to disinfect the surfaces in the room area. The support tower may include at least one air inflow vent configured to draw in room air, at least one air sanitizing unit configured with at least one array of UV light emitting diodes (LEDs), and at least one discharge vent configured to emit sanitized air.
Patent CA-3195203-A1 (CA)
Title: Element de base reglable pour meubles inclinables et meubles inclinables
Inventor: SZPYT ADAM ROMAN
IPC: A47C20/04
Filed: 2021-10-08
Abstract: L'invention concerne un élément de base (100) et un meuble pour s'allonger qui comprend un élément de base et un matelas. L'élément de base comprend un élément formant châssis (101 a) qui est formé au moins partiellement à partir d'un matériau déformable élastiquement, en particulier partiellement à partir de mousse, et qui comprend un compartiment (102). L'élément de base comprend également une couche de couverture (101 b) au moins partiellement déformable élastiquement, cette couche de couverture (101 b) étant disposée sur le deuxième côté (116) de l'élément formant châssis de sorte que le compartiment (102) soit au moins partiellement délimité par la couche de couverture (101b), et ladite couche de couverture (102b) comprend une surface de support qui est disposée à l'opposé de la surface inférieure (118), pour un matelas. L'invention concerne également un dispositif de réglage (300) qui est au moins partiellement disposé dans le compartiment (102) de l'élément formant châssis (101a), le dispositif de réglage (300) comprenant au moins un élément d'entraînement (108) et un mécanisme d'entraînement accouplé à l'élément d'entraînement et est conçu pour déformer l'élément de base (100) et/ou un matelas (202) déposé sur l'élément de base au moins dans certaines zones, ledit mécanisme d'entraînement (108) comprenant au moins deux rails (104, 104') qui sont disposés sensiblement de manière parallèle à un axe longitudinal de l'élément de base (100) et qui sont espacés l'un de l'autre parallèlement à un axe transversal de l'élément de base (100) par l'intermédiaire d'au moins une entretoise transversale (103); chacun des au moins deux rails (104, 104') comprenant au moins deux éléments formant rails (105a-105c) disposés parallèlement à la direction longitudinale l'un derrière l'autre et étant accouplés l'un à l'autre par l'intermédiaire d'au moins une articulation, les au moins deux éléments formant rails de chaque rail pouvant ainsi être déplacés les uns par rapport aux autres par l'intermédiaire du ou des éléments d'entraînement (108, 108').
Patent CA-3197246-A1 (CA)
Title: System for managing a network of personal safety accessories
Inventor: KISH NITZAN
IPC: G08B21/04
Filed: 2021-11-04
Abstract: A personal safety system is provided herein. The system may include: (i) at least two connectable personal accessories, each having at least one sensor to detect a specified event; and a processor to connect the accessory to at least one data network and communicate a detection over the network; (ii) a server; and (iii) at least two instances of an app on respective at least two devices communicatively connected to the at least two accessories. The processor of a first accessory is configured to communicate a detection to a first instance of the app on a first personal device and the first instance app is configured to forward the detection to the server. The server is configured to connect to at least one second instance of the app on a second personal device and communicate the detection to the at least one second instance app.
Patent CA-3200188-A1 (CA)
Title: Procede de construction et application d'un medicament et d'un vaccin a base de proteines multivalentes a mediation par multimerisation d'acide nucleique
Inventor: YANG FAN
IPC: A61K38/37
Filed: 2021-11-25
Abstract: L'invention concerne un procédé de construction et une application d'un médicament et d'un vaccin à base de protéines multivalentes à médiation par multimérisation d'acide nucléique. L'invention concerne spécifiquement un complexe multimère basé sur des squelettes d'acides nucléiques complémentaires. Le complexe est un multimère formé par complexation de monomères 3-6 ayant des squelettes d'acide nucléique complémentaires, chaque monomère étant un polypeptide ayant un brin unique d'acide nucléique. Dans le multimère, le brin unique d'acide nucléique de chaque monomère et les brins uniques d'acide nucléique des deux autres monomères forment des doubles brins au moyen d'une complémentation de base, de manière à former des structures de squelette d'acide nucléique complémentaires. L'invention concerne également une composition pharmaceutique contenant le complexe multimère, une bibliothèque de séquences d'acides nucléiques utilisée pour construire le complexe multimère, et un procédé d'optimisation de squelettes d'acides nucléiques complémentaires. Au moyen du procédé, des médicaments ou des antigènes protéiques à action courte hors du rayon peuvent être utilisés pour compléter la formation multivalente de médicaments ou d'antigènes protéiques sans nécessiter la reconstruction de protéines de fusion ou la modification chimique et la réticulation, ce qui permet d'améliorer leur demi-vie et leur activité et/ou leur immunogénicité.
Patent CA-3201576-A1 (CA)
Inventor: MORTENSEN PETER MOLGAARD
IPC: C01B3/38
Filed: 2021-12-14
Abstract: The invention relates to a method and a system for upgrading a hydrocarbon-contain-ing feed gas to a methanol product stream and a hydrogen product stream. As part of the method/system, a synthesis gas stream is compressed to a pressure being higher than the feed pressure of the hydrocarbon feed gas, prior to being fed to a methanol synthesis unit. A hydrogen product stream is provided by separating a hydrogen rich stream, downstream the methanol synthesis unit.
Patent CA-3203311-A1 (CA)
Title: Towed tillage implement with gauge indicating angular orientation of toolbar
Inventor: REDEKOP JOHAN
IPC: A01B21/08
Filed: 2018-12-04
Abstract: A tillage implement has a main frame towed in a forward working direction and toolbar assemblies supported on the main frame. Each assembly has an elongate toolbar member transverse to the forward working direction with tillage units spaced along the toolbar member for working the ground. A pivot supports each toolbar at an intermediate location on the toolbar for angular adjustment about an upright axis relative to the main frame. Followers at opposing ends of each toolbar member are received in respective guides at fixed locations on the main frame such that the followers are slidable within the guides in the forward working direction while restricting rotation of the toolbar member about a longitudinal axis of the toolbar member relative to the main frame. Angular position of each toolbar is controlled by an actuator with an attached mechanical indicator that can be read by an operator.
Patent CA-3205526-A1 (CA)
Inventor: LOPEZ JOSE
IPC: C25B9/70
Filed: 2022-01-21
Abstract: Un procédé d'autonettoyage d'une cellule électrolytique consiste à introduire un courant d'eau de mer à l'intérieur de la cellule électrolytique possédant au moins une cathode et une anode. La cathode et l'anode sont sensiblement entièrement revêtues d'une composition de revêtement. Une polarisation directe est appliquée entre l'anode et la cathode à une première densité de courant à mesure que l'eau de mer circule entre les électrodes. Ensuite, une polarisation inverse est fournie au niveau de la cathode. La polarisation inverse est fournie à une seconde densité de courant qui est inférieure à la première densité de courant. Lorsque la polarisation inverse est appliquée, la polarité de la cathode est inversée pendant une courte durée. Ceci facilite la génération d'une petite quantité d'acide chlorhydrique au niveau de la surface de cathode précédente provoquant la dissolution du calcium, du magnésium ou d'autres dépôts sur la surface des électrodes sans endommager la composition de revêtement sur les électrodes.
Patent CA-3208919-A1 (CA)
Inventor: JULKUNEN HELI
IPC: G01N33/68
Filed: 2022-02-16
Abstract: A method for determining whether a subject is at risk of developing a digestive system disease is disclosed.
Patent CA-3210043-A1 (CA)
Inventor: DUDLEY SAMUEL
IPC: C07C205/02
Filed: 2021-03-04
Abstract: L'invention concerne un composé de formule (I), ou un sel de celui-ci, A, B, R1, R2, R3 et X ayant l'une quelconque des valeurs indiquées dans la description, ainsi que des compositions comprenant un composé de formule I. De tels composés sont utiles en tant qu'agents thérapeutiques pour le traitement d'un dysfonctionnement diastolique.
Patent CA-3213052-A1 (CA)
Inventor: BRANDT MICHAEL D
IPC: B01D65/10
Filed: 2022-05-03
Abstract: A single-use valve arrangement that includes a valve housing, a diaphragm carried by the valve housing, a pressure sensor, and a controller coupled to the pressure sensor. The valve housing defines an inlet and an outlet, the inlet adapted to be fluidly connected to an outlet of a virus removal filter. The diaphragm divides the valve housing into a first chamber and a second chamber fluidly isolated from the first chamber. The pressure sensor is configured to measure a pressure change in the second chamber due to movement of the diaphragm responsive to a pressure change in the first chamber. The controller is configured to determine an actual leak rate of the filter based on the measured pressure change, the controller further configured to determine the integrity of the filter by comparing the actual leak rate to an expected leak rate of the filter.
Patent CA-3214408-A1 (CA)
Inventor: HUNG DAVID
IPC: C07D491/22
Filed: 2022-03-22
Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
Patent CA-3216556-A1 (CA)
Title: Reinforced non-stick coating system
Inventor: SPERINDIO MATTEO
IPC: C09D183/04
Filed: 2022-05-11
Abstract: Coating compositions that may be applied to the surface of a substrate to form a durable non-stick coating. The coating compositions may include a basecoat composition and an overcoat composition for forming a basecoat and an overcoat applied over the basecoat. The basecoat may comprise one of an organic polymer, a sol-gel composition, and a silicon resin. The basecoat composition and resulting basecoat may further include reinforcing particles. The overcoat may comprise a siloxane matrix formed from one of a hydrosilylation reaction, a dehydrogenative coupling, and a polycondensation reaction. The basecoat and overcoat may each be substantially free of fluoropolymer components.