baber/WOPTO huggingface dataset:
Patent BR-112022024768-A2 (BR)
Title: Proteínas de alvejamento a b7h3 e métodos de uso das mesmas
Inventor: MARTIN FELICES
IPC: C07K16/44
Filed: 2021-06-03
Abstract: PROTEÍNAS DE ALVEJAMENTO A B7H3 E MÉTODOS DE USO DAS MESMAS. A presente invenção refere-se a compostos multiespecíficos de alvejamento a B7H3 e métodos de uso dos mesmos. Os compostos multiespecíficos incluem proteínas de alvejamento biespecíficas incluindo um domínio de alvejamento a B7H3 e um domínio de engate de célula imune; e proteínas de alvejamento triespecíficas incluindo um domínio de alvejamento a B7H3, um domínio de engate de célula imune e um domínio de ativação de célula imune. Os métodos de uso incluem métodos para induzir extermínio celular mediado por NK, métodos para induzir expansão de NK in vivo e métodos para tratar câncer.
Patent BR-112023003129-A2 (BR)
Title: Película de proteção de infravermelho próximo e método para produzir película de proteção de infravermelho próximo
Inventor: KENJI ADACHI
IPC: C09K3/00
Filed: 2021-08-20
Abstract: PELÍCULA DE PROTEÇÃO DE INFRAVERMELHO PRÓXIMO E MÉTODO PARA PRODUZIR PELÍCULA DE PROTEÇÃO DE INFRAVERMELHO PRÓXIMO. Uma película de proteção de infravermelho próximo incluindo uma película contínua de um óxido composto de césio e tungstênio representado por uma fórmula geral CsxWyOz, onde 4,8 = x = 14,6, 20,0 = y = 26,7, 62,2 = z = 71,4, e x + y + z = 100, é fornecido. A película contínua inclui um ou mais cristais selecionados a partir de um cristal ortorrômbico, um cristal romboédrico e um cristal hexagonal.
Patent BR-112023004423-A2 (BR)
Title: Método para melhorar a textura e a funcionalidade de uma bebida à base de concentrado de proteína vegetal fracionada a seco
Inventor: TIMOTHY JAMES WOOSTER
IPC: A23C3/02
Filed: 2021-09-10
Abstract: MÉTODO PARA MELHORAR A TEXTURA E A FUNCIONALIDADE DE UMA BEBIDA À BASE DE CONCENTRADO DE PROTEÍNA VEGETAL FRACIONADA A SECO. A presente invenção refere-se, de modo geral, a um método para fabricação de um líquido à base de plantas, sendo que o dito método compreende dispersar triglicerídeo em uma mistura de proteína vegetal; formar uma emulsão; aplicar um tratamento térmico à emulsão; e aplicar um tratamento de cisalhamento à emulsão termicamente tratada para formar um líquido à base de plantas
Patent BR-112023012529-A2 (BR)
Title: Deleção genômica na vacina da peste suína africana que permite o crescimento eficiente em linhagens de células estáveis
Inventor: DOUGLAS P GLADUE
IPC: C07K14/005
Filed: 2021-03-25
Abstract: deleção genômica na vacina da peste suína africana que permite o crescimento eficiente em linhagens de células estáveis. são fornecidos detalhes sobre a construção de uma vacina viva atenuada do vírus da peste suína africana (asfv) para prevenção de peste suína africana (asf) causada por várias cepas de asfv, como o isolado altamente virulento georgia 2007 (asfv-g). uma vacina exemplar compreende uma deleção de múltiplos genes, permitindo o crescimento em escala industrial em linhagens celulares estáveis.
Patent BR-112023018749-A2 (BR)
Title: Ferramenta de bombeamento de fundo de poço
Inventor: FARAOUN ABDERRAHMANE
IPC: E21B37/00
Filed: 2022-03-21
Abstract: ferramenta de bombeamento de fundo de poço. a presente invenção refere-se ao uso de uma ferramenta de bombeamento de fundo de poço para remover uma formação de hidratos que formam um tampão de hidrato em uma tubulação em um poço, a ferramenta de bombeamento de fundo de poço compreendendo uma bomba com uma entrada e uma saída de bomba, um motor elétrico para acionar a bomba, um cabeamento para alimentar o motor elétrico, a bomba tem uma primeira extremidade disposta mais próxima do cabeamento e uma segunda extremidade voltada para o tampão de hidrato, em que a entrada da bomba está disposta na segunda extremidade e a entrada da bomba entra em contato com uma primeira face do tampão de hidrato, a bomba fornece sucção para remover pelo menos parte de uma pluralidade de moléculas de gás do tampão de hidrato para dissolver pelo menos parte da formação de hidratos. a invenção também se refere a um método de remoção de hidratos para remover a formação de hidratos que formam um tampão de hidratos em uma tubulação.
Patent BR-112023018945-A2 (BR)
Title: Composições e métodos para melhorar a função mitocondrial
Inventor: SCHMERGEL GREG
IPC: A61K36/00
Filed: 2022-03-18
Abstract: composições e métodos para melhorar a função mitocondrial. são revelados métodos para tratar ou prevenir a disfunção mitocondrial. são revelados métodos para tratar ou prevenir uma doença ou condição associada à disfunção mitocondrial ou a um sintoma das mesmas. são revelados métodos para tratar ou prevenir uma doença crônica associada ao envelhecimento ou condição relacionada à disfunção mitocondrial ou um sintoma das mesmas. são revelados métodos para melhorar ou prevenir uma diminuição no nível de energia e/ou vitalidade. os métodos incluem a administração de um extrato de emblica ou um composto constituinte de um extrato de emblica, ou extrato de fucus ou um composto constituinte de um extrato de fucus, ou um extrato de chebula ou um composto constituinte de um extrato de chebula.
Patent CZ-1395-A3 (CZ)
Title: Minimization method of activated protein c degradation and pharmaceutical preparation containing the activated protein c
Inventor: PROUTY WALTER FRANCIS
IPC: C07K14/47
Filed: 1995-01-03
Abstract: The present invention relates to methods to prevent or minimize autodegradation of activated protein C. The invention is best exemplified by performing the processing, purification and/or storage of the activated protein C at low pH, for example at about pH 6.3 to about pH 6.5. Autodegradation of aPC may also be minimized by incubating the aPC in 3 M urea (complete recovery of aPC activity is obtained after the removal of the denaturant) or by incubating the aPC in the presence of extreme salt concentrations. The present invention also comprises aPC formulations which maintain the aPC at low pH, in denaturant, or at extreme salt concentrations.
Patent SK-1796-A3 (SK)
Title: Method and arrangement for controlling heat transfer in ventilation apparatus or air conditioning apparatus
Inventor: SANTAVUORI ESKO T
IPC: F24F11/00
Filed: 1994-07-05
Abstract: PCT No. PCT/FI94/00310 Sec. 371 Date Apr. 30, 1996 Sec. 102(e) Date Apr. 30, 1996 PCT Filed Jul. 5, 1994 PCT Pub. No. WO95/02157 PCT Pub. Date Jan. 19, 1995A method and an arrangement for controlling heat transfer in a ventilation apparatus or an air conditioning apparatus, in which heat contained in exhaust air is recovered into supply air by means of a heat transfer circuit having fluid circulation. Additional heating or additional cooling energy is supplied to the heat transfer circuit when the heat transfer is insufficient for maintaining a desired temperature of the supply air. To optimize the heat recovery, the supply of additional heating or cooling energy is minimized by measuring the temperatures and fluid flows of the heat transfer fluid and of the additional energy.
Patent CZ-21695-A3 (CZ)
Title: Piezo-electric gas sensor and its use
Inventor: FEUCHT GERNOT DR
IPC: H01L41/08
Filed: 1995-01-27
Abstract: Sensor comprises a piezoelectric crystal with a coating contg. polyarylene thioether (I).
Patent CZ-23193-A3 (CZ)
Inventor: NOVOTNY PETR
IPC: B60R25/06
Filed: 1993-02-17
Abstract: Bezpečnostní zařízení sestává z tělesa spojkového válce (1) v němž je umístěný solenoidový ventil (2) a elektronický dekodér (3).
Patent CZ-57293-A3 (CZ)
Title: Peptides with modifiers at n-end, process of their preparation and pharmaceutical preparations in which said peptides are comprised
Inventor: BREIPOHL GERHARD DR
IPC: A61K38/08
Filed: 1993-04-02
Abstract: Peptides of the formula I  Z - P - A - B - C - E - F - K - (D)Q - G- M- F' - I (I),  in which   Z is optionally substituted (cyclo)alk(ano)yl(sulphonyl), (C1-C8)-alkoxycarbonyl, (hetero)ar(o)yl(sulphonyl), carbamoyl,   P is a direct linkage or a radical II  -NR<2>-(U)-CO- (II> in which   R<2> is H, methyl or a urethane protective group,   U is (cyclo)(aryl)alkylidene, (hetero)arylidene or (CHR<3>)n,   R<3> is hydrogen, (cyclo)alkyl, (hetero)aryl, or in which R<2> and R<3> form, together with the atoms carrying them, a ring system;   A is defined as P;   B is a basic amino acid in the L or D configuration,   C is a compound of the formula IIIa or IIIb  G'-G'-Gly (IIIa> G'-NH-(CH2)p-CO (IIIb> in which p is 2 to 8 and   G' are, independently of one another, a radical of the formula IV -NR<4>-CHR<5>-CO- (IV> in which R<4> and R<5> form, together with the atoms carrying them, a heterocyclic ring system; E is the residue of a neutral, acid or basic, aliphatic or alicyclic-aliphatic amino acid; F are, independently of one another, the radical of a neutral, acid or basic, aliphatic or aromatic amino acid, or a direct linkage; (D)Q is D-Tic, D-Phe, D-Dic, D-Thi or D-Nal, or a radical of the formula (V) <IMAGE> in which X is O, S or a direct linkage, and R is H, (cyclo)alkyl or aryl(alkyl),   G is defined as G' above or is a direct linkage; F' is defined as F, is a radical -NH-(CH2)q- with q = 2 to 8 or, if G is not a direct linkage, can be a direct linkage, and   I is -OH, -NH2 or NHC2H5; K is the radical -NH-(CH2)x-CO- with x = 1-4 or is a direct linkage, and   M is defined as F  and their physiologically tolerated salts are described. They have excellent bradykinin-antagonistic action. They are obtained by reacting a fragment with a C-terminal free carboxyl group or its activated derivative with an appropriate fragment with an N-terminal free amino group, or by assembling the peptide stepwise, eliminating one or more protective groups temporarily introduced where appropriate to protect other functionalities in the compound obtained in this way, and converting the compounds of the formula I obtained in this way where appropriate into their physiologically tolerated salt.
Patent CZ-60098-A3 (CZ)
Title: Foil with aperture and process for producing thereof
Inventor: ROLLER JUDITH E
IPC: A61F13/511
Filed: 1996-08-27
Abstract: An apertured film for use as a topsheet in absorbent products wherein the film is corona treated on one side, and has received a surfactant application that is distributed to both the corona treated and non-corona treated sides of the film. A method for application of surfactant includes applying the surfactant to one side of the film and rolling the film into a roll while the surfactant is still wet in order to apply surfactant to both sides of the film.
Patent CZ-60596-A3 (CZ)
Title: Reinforcement of cardboard holder
Inventor: STOUT JAMES T
IPC: B65D5/462
Filed: 1994-09-02
Abstract: A carton for containers such as cans or bottles is formed from a blank (10) that includes a top wall (12), pair of side walls (14, 22) and a bottom wall (18) interconnected to form a tubular structure. End closure structure includes an end flap (30, 34) connected to each end edge of the top wall. Handle apertures (26) are defined in the top wall and positioned thereon generally centrally of the top wall. A handle reinforcing structure includes a pair of end portions (42, 46), one of the end portions connected along a side edge of each of the end flaps and extending to the top edge (32, 36) thereof, and a central portion (50) connected to each of the end portions and extending therebetween. The central portion is secured in overlapping relationship to the top wall (12) and positioned thereon to be substantially adjacent to the handle apertures.
Patent SK-10496-A3 (SK)
Title: Device for phase angular displacement of the upper eccentric shaft of double-eccentric press
Inventor: JAN SLAVKOVSKY
IPC: B30B15/22
Filed: 1996-01-25
Abstract: A device consists of an annular shifting member (6) positioned upon a hub (2) of the upper gear (5) and is provided with lateral teeth engaging into lateral teeth of the upper gear (5). Said upper gear wheel is loosely fit on the upper eccentric shaft (1), and, a pen (3) is inserted between the upper eccentric shaft (1) and its hub (2). The hub (2) is enclosed by a spring (4) pressing upon the shifting member (6). The shifting member (6) has a tangential groove (7). The upper eccentric shaft (1) is preferably provided with a scale.
Patent SK-14998-A3 (SK)
Title: Method for the preparation of halogenated hydroxydiphenyl derivatives and use thereof
Inventor: BURCKHARDT URS
IPC: A01N31/16
Filed: 1998-02-03
Abstract: A 4-stage preparation of halogenated diphenyl ethers of formula (1) is claimed, as are also (A) novel compounds of formula (8a) (ie certain of the oxidised intermediates of formula (8)) and (B) the use of the compounds thus obtained as disinfectants to protect organic materials against attack by microorganisms. The preparation (shown in the reaction scheme below) comprises (i) acylating a halogenated benzene compound of formula (4); (ii) etherifying with a halogenated phenol (6); (iii) oxidising the ether ((7); and (iv) hydrolysing the oxidation product (8). In (1); R1 and R2 = F, Cl or Br; R3 and R4 = H or 1-4C alkyl; m = 1-3; and n = 1 or 2. In (8a) R'1, R'2 and R'3 = F, Cl or Br; and R'4 and R'5 = H or 1-5C alkyl.
Patent SK-36299-A3 (SK)
Title: Method for producing zeolite bodies and zeolite bodies
Inventor: PLEE DOMINIQUE
IPC: B01J20/18
Filed: 1998-07-10
Abstract: The invention concerns a method for obtaining agglomerates of faujasite X comprising at least 95 % of faujasite LSX, i.e. with Si/Al ratio equal to 1, constituting the active adsorbent. The agglomerate is formed from LSX zeolite and a binder capable of zeolitization the transformation of which into active zeolite is obtained by zeolitization in a sodium/potassium or sodium liquor.
Patent SK-46596-A3 (SK)
Title: Outer wall element for buildings, in particular wainscot panel for the breastwork area of the wall of a building
Inventor: SCHULZ HARALD
IPC: F24J2/00
Filed: 1994-10-12
Abstract: The outer wall structure has an outer transparent heat-insulating layer (30) arranged between an outer transparent permeable shell (10) and an inner shell (20), next to the outer shell (10), as well as an inner heat-insulating layer (22) that is part of the inner shell (20). A radiation-permeable separating layer (21') that absorbs an alpha fraction of the solar radiation from the outer heat-insulating layer (30) is located between the outer heat-insulating layer (30) and the inner heat insulating layer (22). The heat transfer resistance Ra of outer shell (10) and outer heat-insulating layer (30) and their total energy transmittance g, as well as the absorbance alpha at the separating layer (21') and the heat transfer resistance Ri of the inner shell (20) with its inner heat-insulating layer (22) are adapted to each other so that at the highest expected insolation and highest outer temperature in summer the separating layer (21') reaches at the most a maximum temperature that can be supported by the materials in the wall structure without damage, whereas the maximum temperature reached at the wall inner surface is still felt as comfortable by persons inside the building.
Patent SK-55798-A3 (SK)
Title: Method and pharmaceutical composition for regulating lipid concentration
Inventor: BOCAN THOMAS M A
IPC: A61K31/22
Filed: 1996-10-02
Abstract: The present invention is a combination of an ACAT inhibitor, for example, sulfamic acid, [[2,4,6,-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester, and an HMG-CoA-reductase inhibitor, for example, atorvastatin, effective for lipid regulation. The combination of agents results in a greater reduction in plasma VLDL and LDL cholesterol and increases HDL cholesterol than either alone resulting in a less atherogenic lipoprotein profile. The combination is useful in the treatment of patients with or at risk of developing ischemic syndromes in order to restore endogenous vascular endothelium-dependent activities.
Patent CH-615561G-A3 (CH)
IPC: H01H13/02
Filed: 1976-06-30
Abstract: An upper metal frame or a bezel and a rear metal frame of an electronic wristwatch are electrically isolated from each other by interposing an insulating frame therebetween. The upper metal frame or the bezel is connected to one input terminal of a touch sensitive electronic switching circuitry disposed in the electronic wristwatch, whereas the rear metal frame is connected to another input terminal of the touch sensitive electronic switching circuitry.
Patent CZ-122891-A3 (CZ)
Title: Apparatus for reading digital audible signal form a master medium
Inventor: DUURLAND JOSEF MARIA
IPC: G11B5/86
Filed: 1991-04-29
Abstract: An arrangement for reading a digital audio signal from a master medium (7) and storing it in a digital storage medium (10, 90, 90') at a first bit rate in a first step, and for repeatedly reading the digital audio signal from the storage medium and recording the digital audio signal on a recording medium (20') at a second bit rate in a second step. The digital storage medium is adapted to store a digital information signal which is a representation of a first music program (M1) and a digital information signal which is a representation of a second music program (M2). The arrangement (Fig. 1b) is further adapted to repeatedly read the information signal representing the first music program and an information signal representing the second music program into the digital storage medium in the second step. <IMAGE>
Patent CZ-100598-A3 (CZ)
Title: Wagon for loose material
Inventor: THEURER JOSEF
IPC: B61D3/00
Filed: 1998-04-02
Abstract: A long ballast truck has a single container (2) with a conveyor in the bottom to transfer ballast to a rising conveyor (8) at one end of the truck to spread onto the track. The weight of the container is supported by two linked flatbeds and with two swivel mountings (19,20) between the flatbeds and the container. One if the swivel mountings (19) has a sliding fitting on its flatbed. The sliding action is provided by a slider (21) moving along the flatbed using an array of rollers.
Patent CZ-115693-A3 (CZ)
Title: Process for preparing low-alcohol beer
Inventor: SROGL JIRI ING
IPC: C12C11/00
Filed: 1993-06-15
Abstract: A process for preparing low-alcohol beer, whose fermentation is divided into two phases. After mashing the beer wort is sieved in the usual way. After cooling to a pitching temperature of 2 to 20 degrees C and after attenuation to the apparent level of attenuation of 40 to 85 % the alcohol is removed by boiling. The vapours containing alcohol are cooled during the boiling and the occurring malt distillate is collected, whereupon the wort is boiled with hops. After sludge separation and cooling to a pitching temperature of 2 to 20 degrees C fresh yeast is added and the beer is after-fermented to the apparent level of attenuation of 40 to 85 %. After after-fermentation it is stored and clarified.
Patent CZ-118393-A3 (CZ)
Title: Hydroxamic acid derivatives, process of their preparation and medicaments based thereon
Inventor: BROADHURST MICHAEL JOHN
IPC: A61K31/16
Filed: 1993-06-07
Abstract: The invention provides hydroxamic acid derivatives of the formula   <CHEM> wherein R<1> represents 1-7C alkyl; R<2> represents hydrogen, 1-6C alkyl or a group of the formula -(CH2)n-aryl or -(CH2)n-Het in which n stands for 1-4 and Het represents a 5- or 6-membered N-heterocyclic ring which (a) is attached via the N atom, (b) optionally contains N, O and/or S as additional hetero atom(s) in a position or positions other than adjacent to the linking N atom, (c) is substituted by oxo on one or both C atoms adjacent to the linking N atom and (d) is optionally benz-fused or optionally substituted on one or more other carbon atoms by 1-6C alkyl or oxo and/or on any additional N atom(s) by 1-6C alkyl; R<3> represents the characterizing group of a natural or non-natural  alpha -amino acid in which any functional group present may be protected, with the proviso that R<3> does not represent hydrogen; R<4> represents carboxyl, (1-6C alkoxy)-carbonyl, carbamoyl or (1-6C alkyl)carbamoyl; R<5> represents the characterizing group of a naturally occurring  alpha -amino acid in which any functional group present may be protected; and R<6> represents hydrogen; or R<4>, R<5> and R<6> each individually represent hydrogen or 1-6C alkyl, and their pharmaceutically acceptable salts, which are matrix metalloproteinase inhibitors useful for the control or prevention of degenerative joint diseases such as rheumatoid arthritis and osteoarthritis or for the treatment of invasive tumours, atherosclerosis or multiple sclerosis. They can be manufactured according to generally known methods by deprotecting a corresponding novel benzyloxyamino compound or hydroxamidating a corresponding novel amino acid or activated derivative thereof.
Patent CZ-178793-A3 (CZ)
Title: PROCESS FOR PREPARING IMIDAZO/4,5-c/QUINOLIN-4-AMINES
Inventor: GERSTER JOHN F
IPC: C07D471/04
Filed: 1992-02-13
Abstract: A process and intermediates for preparing 1-substituted-1H-imidazo[4,5-c]quinolin-4-amines. The process involves reacting a 1-substituted-1H-imidazo[4,5-c]quinoline-5N-oxide with an isocyanate and hydrolysing the product thereof. Also, a process for preparing the intermediates is disclosed.
Patent CZ-184095-A3 (CZ)
Title: Attachment for sectional heating bodies
Inventor: BLAB REINHARD
IPC: F24D19/02
Filed: 1994-02-11
Abstract: The fixing system for sectional heating elements consists of a plurality of fixing members connected to a heating element in order to support the heating element on support members which are anchored in a wall or a floor. Parts of the fixing members are pre-mounted at the factory as clamping elements (2) located at their correct positions between heating element sections (1). The clamping elements (2) are provided with sidepieces (4) which partly wrap round the heating elements (1) and have a recess (5) between them.
Patent CZ-188796-A3 (CZ)
Title: Through-flow regulating valve
Inventor: HAGMANN STEFAN
IPC: G05D7/01
Filed: 1996-06-26
Abstract: The control valve (1) has a first throttle point (8,9) which enables a pressure difference from a second throttle point (4,5) to be controlled to a constant value. The control is carried out by means of a hydraulic drive (12). The latter has a membrane (11) with one side forming a wall of a first pressure chamber (13). The latter is connected to an inlet space (2) of the valve (1). The other side of the membrane (11) forms a wall of a second pressure chamber (15). This is connected to a space (18) behind the second throttle point (4,5). The membrane (11) is connected via a rod (10) to a regulating cone (9) which is a component of the first throttle point (8,9). The second throttle point (4,5) is arranged in the same valve housing (7) as the first throttle point. The second throttle point (4,5) has a cone (4). This is axially movable in steps relative to an opening (5) by means of a valve spindle (21). The cone (4) is made up of at least two relatively movable parts (22,23). The distance between these parts controls the effective cross-section of the throttle point (4,5).
Patent CZ-248799-A3 (CZ)
Inventor: BAGEPALLI BHARAT SAMPATHKUMAR
IPC: F04D29/08
Filed: 1999-07-13
Abstract: Turbínové drážkové těsnění (516) obsahuje podélný turbínový
těsnicí člen (526). Tento turbínový těsnicí člen (526) má
podlouhlou neděrovanou a ohebnou první část a pevnou
druhou část, která v podélnémsměru navazuje na první část.
Těsném (516)je součástí montážní sestavy, která dále
obsahuje první turbínový člen (512) a druhý turbínový člen
(514). Tyto turbínové členy(512, 514)jsou od sebe poněkud
vzdáleny, takže mezi sebou vymezují tekutinovou únikovou
OO, mezeru (515). Vtéto mezeře (515)je umístěn těsnicí člen
(526). Každý podélný okraj (522,524) těsnicího členu (526)
zapadá příslušně dojedné ze dvou protilehlých povrchových
1 drážek prvního a druhého turbínového členu (512,514).