baber/WOPTO huggingface dataset:
Patent CA-2444661-A1 (CA)
Inventor: BRASLAWSKY GARY R
IPC: A61P35/02
Filed: 2002-01-31
Abstract: L'invention concerne des méthodes et des kits utilisés dans le traitement des troubles néoplasiques, comprenant l'utilisation d'un antagoniste CD23. Cet antagoniste CD23 peut être utilisé seul ou il peut être associé à des agents chimiothérapiques. Dans des modes de réalisation préférés, les antagonistes CD23 peuvent être utilisés pour traiter la leucémie lymphoïde cellules B chronique (LLC-B).
Patent CA-2444686-A1 (CA)
Inventor: BUCCERI ALFIO
IPC: F25C3/04
Filed: 2002-04-19
Abstract: A snow making method where water and/or ice is mixed with a cryogenic material, such as carbon dioxide, in a mixing vessel and the mixture is mechanically agitated or mixed to convert the water and/or ice into snow. The cryogenic material may be recovered and recycled for return to the vessel.
Patent CA-2445985-A1 (CA)
Inventor: LU ZHENG-RONG
IPC: A61K41/00
Filed: 2002-05-06
Abstract: A cell-targeted polymeric drug delivery system was designed based on the specific interaction between hyaluronic acid (HA) and its cell surface receptors overexpressed on cancer cell surface. The invention relates to compounds composed of a carrier molecule,5 wherein the carrier molecule contains at least one residue of an anti-cancer agent and at least one residue of a hyaluronic acid. The invention also relates to methods of making and using the compounds thereof.
Patent CA-2446487-A1 (CA)
Inventor: LIPKE ANTHONY P
IPC: B60R13/02
Filed: 2003-10-24
Abstract: A vehicle trim component includes an integrally formed self-retaining fastening device that extends from the vehicle trim component and a passage that permits insertion of a fastener for securing the vehicle trim component to a vehicle structure. The self retaining fastening device further comprises a head portion and a shaft portion. The head portion comprises a rosebud-type fastener surface. The shaft portion extends from the housing and includes at least one row of ribs. The ribs may be angled to provide a relatively lesser amount of force needed for insertion, but a relatively higher amount of force in extraction of the self retaining fastening device. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR  1.72(b).
Patent CA-2446820-A1 (CA)
Inventor: MILLER SHAWN CHRISTOPHER
IPC: C07D471/04
Filed: 2002-05-13
Abstract: Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors. The disclosed invention relates to compounds of the structure (I) wherein (I) is a four, five, or six membered saturated ring and X is C, O or S.
Patent CA-2447416-A1 (CA)
Inventor: DAHMEN PETER
IPC: C07D265/02
Filed: 2002-05-03
Abstract: L'invention se rapporte à de nouvelles benzoylcyclohexenones substituées de formule (I), dans laquelle Q, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, Y et Z ont la signification indiquée dans la description, ainsi qu'à un procédé pour leur production et à leur utilisation.
Patent CA-2452974-A1 (CA)
Title: Decorative tail pipe mounted apparatus for an automobile
Inventor: QUAST SHAWN T
IPC: F01N13/08
Filed: 2003-12-30
Abstract: An apparatus for attachment to the tail pipe of a vehicle is disclosed. The apparatus comprises an elongate bracket operative to be attached to said tail pipe and having an end extendable beyond the end of said tail pipe. The apparatus also comprises an endplate coupled to said end of said bracket. The apparatus also comprises a symbol formed as a part of said endplate and operative to be viewed by an observer outside said vehicle. The apparatus may amuse observers outside the vehicle and mask the normally unappealing appearance of the tail pipe.
Patent CA-2458415-A1 (CA)
Title: 24-sulfur-substituted analogs of 1.alpha.,25-dihydroxy vitamin d3
Inventor: YANG HONG WOON
IPC: A61P15/00
Filed: 2002-08-22
Abstract: The present invention provides novel C24-aryl sulfone analogs of 1.alpha.,25 - dihydroxy vitamin D3 of formula (I) : wherein R1-R7 have the meanings given in the description, x is 0-2; and represents a single or a double bond, compositions comprising these compounds and methods of using these compounds as selective inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit from a modulation o f the levels of 1.alpha.,25-dihydroxy vitamin D3, for example, cell- proliferative disorders.
Patent CA-2458680-A1 (CA)
Title: Verres reconstruits pour applications de fibres optiques
Inventor: CARON SERGE
IPC: C03B37/012
Filed: 2002-10-17
Abstract: L'invention concerne une préforme prévue pour une fibre optique, une fibre optique ainsi obtenue et des procédés permettant de les produire. Cette fibre se caractérise en ce qu'il est prévu d'utiliser du verre poreux dopé avec au moins un dopant. Les fibres qui en résultent peuvent s'utiliser pour produire des fibres à haut degré d'atténuation.
Patent CA-2458835-A1 (CA)
Title: Stator for rotating electrical machine
Inventor: FUKUDA KENJI
IPC: H02K3/52
Filed: 2002-09-03
Abstract: A stator for use in a rotating electrical machine is constituted by arranging the prescribed number of stator units in the circumferential direction of a stator core having a circular ring shape. The stator units provide magnetic teeth that project inwardly in the radial direction of the stator core. Coils are wound about the magnetic teeth via insulating members. Each of the insulating members arranges thick portions that slightly project opposite to each other in the width direction of the magnetic tooth, wherein the thick portions are shifted in positions in the thickness direction of the stator core with respect to opposite sides of the magnetic teeth arranged opposite to each other. Thus, it is possible to noticeably improve the space factor in the stator.
Patent CA-2459691-A1 (CA)
Title: Seal feature to prevent bending
Inventor: KOCH STEVE GEORGE
IPC: F16J15/12
Filed: 2004-03-04
Abstract: A gasket for statically sealing between two members is disclosed. The gasket includes a first generally planar portion having an inner perimeter and an exterior perimeter, and having a first surface and a second surface on an opposite side from the first surface.  A seal bead rises from the first surface a first predetermined height and extends about the inner perimeter. A fastener hole extends through the first portion and is located between the seal bead and the exterior perimeter. The gasket also includes a seal feature located between the fastener hole and the exterior perimeter that rises from the first surface a second predetermined height that is about equal to or greater than the first predetermined height.
Patent CA-2459903-A1 (CA)
Inventor: PFUTZNER KATHARINA
IPC: G11B23/03
Filed: 2002-09-10
Abstract: A DVD case (1) is of integral one-part moulded plastics construction. A  retainer (15) has two opposed retainer parts (32) having lips (33) for engagement of a DVD at opposed sides of its central aperture. The DVD is released by the parts (32) being moved closer together. However there is no need for the user to press them directly. He or she simply presses a push-button (20) at the edge of the seat, causing the parts (32) to move together in a simple action caused by an integrally moulded release mechanism (16, 17).
Patent CA-2461037-A1 (CA)
Title: Differential signal electrical connectors
Inventor: COHEN THOMAS S
IPC: H01R12/71
Filed: 1999-11-24
Abstract: An electrical connector for transferring a plurality of differential signals between electrical components. The connector is made of modules that have a plurality of pairs of signal conductors with a first signal path and a second signal path. Each signal path has a pair of contact sections extending between the contact portions.      For each pair of signal conductors, a first distance between the interim sections is less than a second distance between the pair of signal conductors and any other pair of signal conductors of the plurality. Embodiments are shown that increase routability.
Patent CA-2461925-A1 (CA)
Inventor: DE BRUIJN JOOST DICK
IPC: A61L24/00
Filed: 2002-09-30
Abstract: La présente invention concerne un charge osseuse comportant des particules de sel de calcium, un liant organique présentant une affinité pour le phosphate de calcium, des cellules choisies parmi le groupe de cellules souches, les cellules ostéogéniques, les cellules souches d'origine osseuse et un tampon pharmaceutiquement acceptable. La charge osseuse de l'invention présente le grand avantage de constituer une formulation injectable permettant son introduction dans une déficience osseuse à travers l'aiguille d'une seringue.
Patent CA-2469301-A1 (CA)
Inventor: SAITO KYOICHI
IPC: C12N15/09
Filed: 2002-10-23
Abstract: Compositions are provided herein comprising a material having engrafted polymer brushes. The polymer brushes further comprise one or more functional groups immobilized along the surface of the brushes in a plurality of layers, which confer functional properties to the material compositions. These materials are useful in material libraries for high throughput separation studies, and for the isolation or transfection of microorganisms and cells.
Patent CA-2471385-A1 (CA)
Title: Medicaments pour la prevention et le traitement du cancer
Inventor: HIKICHI YUICHI
IPC: A61K48/00
Filed: 2002-12-26
Abstract: Un composé ou son sel régulant l'activité d'une protéine possédant une séquence d'acides aminés qui est identique ou sensiblement identique à la séquence d'acides aminés représentée par SEQ ID NO:1, un nucléotide antisens contenant une séquence de base ou une partie de celle-ci, qui est complémentaire ou sensiblement complémentaire à la séquence de base d'un ADN codant pour une protéine ou son peptide partiel possédant une séquence d'acides aminés qui est identique ou sensiblement similaire à la séquence d'acides aminés représentée par SEQ ID NO:1; on peut les utiliser comme médicaments destinés à la prévention et au traitement du cancer.
Patent CA-2471674-A1 (CA)
Inventor: L ESPERANCE ANDRE
IPC: G10K11/175
Filed: 2004-06-21
Abstract: A system and method for generating a masking noise level and spectrum automatically adjusted to obtain a target masking noise spectrum in a room.   The system comprises a white noise generator and a mask filter automatically determined according to a correction of an acoustical response of the room and to the target masking noise corrected by an ambient noise.
Patent CA-2474036-A1 (CA)
Inventor: TILLEY GREG A
IPC: G01N21/64
Filed: 2002-11-07
Abstract: Une onde laser excite une particule biologique. Des canaux de détection sont créés pour détecter une lumière diffusée par cette particule biologique et pour détecter toute auto-fluorescence émise par cette particule biologique. Des canaux additionnels peuvent aussi détecter la lumière émise par une auto-fluorescence de la particule biologique lorsqu'elle est simultanément excitée par la lumière à des harmoniques de la longueur d'onde fondamentale du laser. La particule biologique est identifiée par diffusion de Mie et des calculs de mesure de rapports d'auto-fluorescence générés par le calcul de rapports de hauteurs de crête détectées ou de valeurs d'impulsion intégrée dans les canaux fournissent des informations additionnelles destinées à identifier et à classer cette particule biologique. Un avertissement ou une alarme peut être déclenché si la particule biologique est une particule d'intérêt.
Patent CA-2475731-A1 (CA)
Inventor: SCHWOERER ARTUR
IPC: E04G11/08
Filed: 2004-07-26
Abstract: The invention concerns a formwork system (1) for forming a transition of reinforcement (8) between a concrete component and a further concrete component located adjacent thereto in a connecting direction (14), comprising two formwork elements (2, 3) and a central element (5), wherein the central element is disposed between the formwork elements in the region of one end of the formwork elements, and wherein elastic sealing lips (7) are disposed each between the formwork elements (2, 3) and the central element (5), which is characterized in that the formwork system comprises mounting positions (40-43) for spacers (6; 32-39), wherein one mounting position (41, 42) each is provided on the two outer sides, of the central element, facing the formwork elements, and one mounting position (40, 43) each is provided on the inner sides of the formwork elements opposite to these outer sides of the central element, several spacers can be mounted on top of each other at each mounting position, at least one spacer is mounted to each mounting position and one elastic sealing lip is disposed on at least one uppermost spacer (33, 34, 37, 38) of each of the two opposite mounting positions. This permits production of concrete components of any wall thickness and concrete cover depth.
Patent CA-2478239-A1 (CA)
Inventor: KIENER PETER
IPC: C07K16/28
Filed: 2003-03-04
Abstract: La présente invention concerne des méthodes et des compositions élaborées pour le traitement, la gestion ou la prévention de cancer. Ces méthodes comprennent l'administration d'une quantité efficace d'au moins un antagoniste de l'intégrine ?<SB>V</SB>?¿3? seul ou combiné à l'administration d'une quantité efficace d'au moins un autre agent utilisé en cancérothérapie. Cette invention a également pour objet des compositions pharmaceutiques renfermant au moins un antagoniste de l'intégrine ?<SB>V</SB>?¿3? et/ou au moins un autre agent utilisé en cancérothérapie. Plus spécifiquement, ladite invention a trait à des méthodes de traitement et de prévention de cancer reposant sur l'administration d'une quantité efficace sur le plan thérapeutique ou prophylactique d'au moins un antagoniste de l'intégrine ?<SB>V</SB>?¿3? seul ou combiné à des thérapies traditionnelles et expérimentales destinées au traitement ou à la prévention de cancer. Cette invention concerne aussi des méthodes de criblage d'antagonistes de l'intégrine ?<SB>V</SB>?¿3? spécifique d'un épitope qui peuvent être utilisés en fonction des méthodes de cette invention, ainsi que des méthodes servant à faciliter l'utilisation des antagonistes de l'intégrine ?<SB>V</SB>?¿3 ?dans l'analyse de l'expression de l'intégrine ?<SB>V</SB>?¿3? dans des biopsies d'échantillons d'études cliniques et de modèles d'animaux.
Patent CA-2478470-A1 (CA)
Title: Solubilization of weak bases
Inventor: YALKOWSKY SAMUEL H
IPC: A61K31/4188
Filed: 2003-03-26
Abstract: A pharmaceutical composition for administration to mammals comprising: a weak base compound having a compound pKa below about 7; an acidic buffer with a buffer pKa below 7; and optional pharmaceutically acceptable additives, wherein the composition has a pH below about 4 is provided. Preferred pharmaceutically active compounds are imidazole derivatives, pyridine derivatives, and aniline derivatives. The pharmaceutical compositions have greater water solubility than the weak base.
Patent CA-2478622-A1 (CA)
Title: Oil based drilling fluid
Inventor: MARANGONI DANIEL GERARD
IPC: E21B7/00
Filed: 2004-08-20
Abstract: A method of forming bore holes in conventional and non-conventional hydrocarbon deposits, comprising the steps of circulating a drilling fluid through the bore hole during the drilling thereof, the drilling fluid being oil based.
Patent CA-2479246-A1 (CA)
Title: Procede de surexpression de polysaccharides zwitterioniques
Inventor: COYNE MICHAEL J
IPC: C07K14/32
Filed: 2003-03-13
Abstract: L'invention concerne des procédés de production et de sélection de nouvelles souches de mutants de <i>B. fragilis</i> exprimant de manière constitutive un polysaccharide capsulaire spécifique ou uniquement des polysaccharides capsulaires sélectionnés; ainsi que des compositions dirigées contre les nouvelles souches de mutants de <i>B. fragilis</i> exprimant de manière constitutive un polysaccharide capsulaire spécifique ou uniquement des polysaccharides capsulaires sélectionnés; et des procédés améliorés de purification de polysaccharides capsulaires individuels et des compositions dirigées contre des nouveaux gènes res02 et inv19 et leurs produits géniques. L'invention concerne également des procédés et des compositions de surexpression et de purification de polysaccharides capsulaires immunomodulateurs A (PSA) à un rendement élevé.
Patent CA-2483226-A1 (CA)
Inventor: FERREE BRET A
IPC: A61F2/00
Filed: 2003-04-23
Abstract: This invention improves upon prior aft total disc replacements (TDRs) by more closely replicating the kinematics of a natural disc. The preferred embodiments feature two or more fixed centers of rotation (CORs) and an optional variable COR (VCOR) as the artificial disk replacement (ADR) translates from a fixed posterior COR that lies posterior to the COR of the TDR to facilitate normal disc motion. The use of two or more CORs allows more flexion and more extension than permitted by the facet joints and the artificial facet (AF). AF joint-like components may also be incorporated into the design to restrict excessive translation, rotation, and/or lateral bending.
Patent CA-2483261-A1 (CA)
Title: Pwm controller with automatic low battery power reduction circuit and lighting device incorporating the controller
Inventor: KRIEGER MICHAEL
IPC: H05B41/285
Filed: 2003-04-28
Abstract: A controller for controlling a voltage applied to a load (500) from a power source (100) includes a square wave producing circuit (300) for connection i n the circuit with the battery and the lamp. The square wave producing circuit (300) produces a variable duty cycle square wave for controlling application of power to the load in accordance with the duty cycle of the square wave in response to a voltage at the control input. A voltage varying circuit is connected to the power source for producing a selectively variable voltage that is fed to the control input of the square wave producing circuit for selectively adjusting the duty cycle of the square wave. A low voltage detection circuit (400) is connected to the power source and coupled to the control input of the square wave producing circuit for automatically produci ng a voltage that decreases the duty cycle of the square wave when the battery voltage decreases to or below a predetermined level.
Patent CA-2484112-A1 (CA)
Inventor: ATTIA OMAR S
IPC: G06K19/077
Filed: 2003-04-18
Abstract: Des étiquettes d'identification par radiofréquences sont produites qui présentent une impression variable personnalisée. Des feuilles de papier sont utilisées pour former une structure simple et peu onéreuse, pour supporter et protéger des radiobalises d'identification par radiofréquences. La structure du papier sert également de surface pour une impression variable personnalisée à l'aide d'imprimantes laser. La structure comprend une feuille de base, une feuille de couverture sur laquelle une image appliquée par impression laser est formée par passage de l'ensemble de feuilles dans la trajectoire de l'imprimante laser, et une feuille de masque comportant au moins une fenêtre. Les feuilles forment une poche de protection dans la fenêtre pour protéger un circuit électronique contre la chaleur et la pression appliquées par l'imprimante laser lors de l'impression de l'image sur la feuille de couverture. Après l'impression, la structure peut être séparée en multiples étiquettes d'identification par radiofréquences. Les informations d'identification sont transmises depuis les circuits électroniques à l'intérieur des poches de protection à un récepteur externe.
Patent CA-2484622-A1 (CA)
Inventor: AMMAR MAHMOUD
IPC: G09F13/00
Filed: 2004-10-28
Abstract: An illuminated alpha-numeric display assembly includes a body and a plurality of lights shaped as individual alpha-numeric characters. The body has a linear array of conductive connection points. Each light has either male connectors or female connectors adapted for connection with one of the conductive connection points on the body. By connecting to the linear array of conductive connection points of the body in a sequential order a series of lights in the shape of alpha-numeric characters is able to create an alpha-numeric display. The display assembly is useful for building addresses, static signage, or advertising messages.
Patent CA-2487208-A1 (CA)
Title: An apparatus for cutting a web with a water jet
Inventor: KOSKINEN JUKKA P
IPC: D21G9/00
Filed: 2004-11-09
Abstract: The invention relates to an apparatus particularly for cutting a web with a water jet.     The apparatus comprises support and positioning elements and a cutter head supported by them and extending to the edge part of the web (14) in the operating position. The cutter head comprises a support surface (13) provided with e.g. nodules (13.1-13.4) and at least one nozzle (28), which is so set that the edge part travels between the support surface (13) and the nozzle (28).
Patent CA-2487475-A1 (CA)
Title: Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome
Inventor: SPINDLER JEAN-FRANCIS
IPC: C07D213/64
Filed: 2003-06-02
Abstract: La présente invention a pour objet un procédé de création d'une liaison carbone-carbone ou carbone-hétéroatome par réaction d'un composé insaturé porteur d'un groupe partant et d'un composé nucléophile. L'invention vise notamment la création de liaison carbone-azote selon un procédé d'arylation de dérivés organiques azotés. Le procédé, selon l'invention, de création d'une liaison carbone-carbone ou carbone-hétéroatome par réaction d'un composé insaturé porteur d'un groupe partant et d'un composé nucléophile apportant u n atome de carbone ou un hétéroatome (HE) susceptible de se substituer au grou pe partant, créant ainsi une liaison C-C ou C-HE, est caractérisé par le fait q ue la réaction a lieu en présence d'une quantité efficace d'un catalyseur à bas e de cuivre et d'au moins un ligand comprenant au moins une fonction imine et au moins un atome d'azote supplémentaire comme atomes de chélation.
Patent CA-2488720-A1 (CA)
Inventor: CARSON DAVID R
IPC: G06F17/00
Filed: 2003-06-10
Abstract: An ergonomic control system (58) is disclosed for monitoring and /or controlling ergonomic settings (120) of one or more adjustable furniture units (122) at a user's worksite. The furniture units (90) may include, e.g., talbe, a chair, a worksite lighting mechanism, a thermostat, computer monotor, and computer keyboard, and a phone. The control system is distributed over a network, with a central administration subsystem (54) receiving ergonoric current setting data regarding adjustable furniture units from worksites in use. Such current setting data is associated with the current worksite user and stored for subsequent comparison with preferred ergonomic settings thereby to identify uers whose setting may be determental to their health.
Patent CA-2488903-A1 (CA)
Title: Dc/dc converter including a zener diode having a substantially zero temperature coefficient
Inventor: YOSHINO TORU
IPC: H02M1/10
Filed: 2004-11-29
Abstract: A DC/DC converter has a transformer having a primary winding (N P), a secondary winding (N S), and an auxiliary winding (N B), a switching transistor (Q1) connected in series to the primary winding, a control transistor (Q2) for turning the switching transistor on or off, and a feedback control circuit connected to the control transistor and the auxiliary winding. The feedback control circuit includes a Zener diode (D5) having a substantially zero temperature coefficient. The Zener diode (D5) has a Zener voltage which lies in a range between 5 volts and 6 volts. In order to cancel a temperature characteristic of the control transistor (Q1), the temperature coefficient of the Zener diode (D5) is selected.