Patent CR-20210558-A (CR)
Title: Compuestos antivirales que contienen nitrilo
Inventor: TUTTLE JAMISON BRYCE
IPC: C07D497/04
Filed: 2021-08-06
Abstract: La invención se refiere a compuestos de la Fórmula I <img src="data:image/png;base64,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 (***)