baber/WOPTO huggingface dataset:
Patent JP-2001518930-A (JP)
IPC: A61K51/00
Filed: 1998-03-17
Abstract: B-Cell malignancies, such as the B-cell subtype of non-Hodgkin's lymphoma and chronic lymphocytic leukemia, are significant contributors to cancer mortality. The response of B-cell malignancies to various forms of treatment is mixed. Traditional methods of treating B-cell malignancies, including chemotherapy and radiotherapy, have limited utility due to toxic side effects. Immunotherapy with anti-CD20 antibodies have also provided limited success. The use of antibodies that bind with the CD22 antigen, however, provides an effective means to treat B-cell malignancies such as indolent and aggressive forms of B-cell lymphomas, and acute and chronic forms of lymphatic leukemias. Moreover, immunotherapy with anti-CD22 antibodies requires comparatively low doses of antibody protein, and can be used effectively in multimodal therapies.
Patent JP-2001522457-A (JP)
Title: 電磁流量計
IPC: G01F1/00
Filed: 1998-04-24
Abstract: (57)【要約】
流量測定ダクトと、ダクトの中を流れる流体の中に流れの方向を横切って磁界を発生する手段と、それによって流体の中に流れを示すものとして誘起された電圧を測定する手段とを有する電磁流量計の動作方法であって、この方法は、磁界がない場合における測定手段の出力を測定することと、それからダクトの中の流体の有無を決定することとを含む。
Patent JP-2002502482-A (JP)
Title: 大容量ガス貯蔵および供給システム
IPC: H01L21/265
Filed: 1998-05-20
Abstract: (57)【要約】
物理的収着媒（１４）上において収着可能であり、かつ、収着後に、圧力を媒介とした脱着および／または熱を媒介とした脱着によってその収着媒から脱着可能である流体を貯蔵しかつ要求があり次第供給するためのシステム。このシステムは、物理的収着媒（１４）を含む貯蔵および供給容器と、脱着ガス保持構造体、たとえば貯蔵容器（１０１）、または延長された長さのガス流通導管を含み、これは、物理的収着媒（１４）から脱着し保持構造体（１１２）に流れ込む流体を後の放出のため保持する。ポンプ（１０８）は、貯蔵および供給容器（１０１）との間でガスを流通させるよう作動的に結合され、脱着流体を保持構造体（１１２）に転送してそこにて保持させる。作動アセンブリ（１２０）は、保持構造体（１１２）内で保持される流体の圧力をモニタし、それに応答してポンプ（１０８）を制御して、所定の圧力範囲および量の流体を保持構造体（１１２）内に維持して後にそこから放出する。
Patent NZ-214549-A (NZ)
Title: Expression control dna sequences
Inventor: BUJARD H
IPC: C12N15/72
Filed: 1985-12-13
Abstract: New expression control sequences useful in the expression of pro- or eukaryotic proteins in prokaryotic organisms are provided comprising a coliphage T5 promoter combined with a DNA sequence which permits the control of promoter activity. Also described are expression vectors containing these expression control sequences and processes using same for the manufacture of pro- or eukaryotic polypeptides.
Patent NZ-220606-A (NZ)
Title: Method and reactor vessel for the fermentative preparation of polysaccharides
Inventor: OOSTERHUIS NICOLAAS MARIUS GER
IPC: C12P19/06
Filed: 1987-06-08
Abstract: For the fermentative preparation of polysaccharides, in particular xanthane, water, production medium (sugars, nutrient salts), and an inoculation material of a suitable aerobic bacterium are mixed in a reactor as reaction components, the production medium being exposed to fermentation while an oxygen-containing gas is being supplied. The object is to avoid the usual low yield of such a process and to reject an expensive and sensitive alternative construction (circulation tube). According to the invention, the reaction components are introduced into a reactor vessel in a circulating flow by means of pumping means, which circulating flow comprises a rising flow and a descending flow which are separated from each other by one or more partitions disposed in the reactor vessel. The mixing is brought about because the rising flow and/or the descending flow is passed essentially in the form of a plug flow through one or more static in-line mixers.
Patent NZ-227439-A (NZ)
Title: Producing self-supporting ceramic bodies by infiltrating molten metal into a mass containing boron carbide
Inventor: CLAAR TERRY DENNIS
IPC: C22C29/02
Filed: 1988-12-21
Abstract: Self-supporting bodies are produced by reactive infiltration of a parent metal (10) into boron carbide (12) typically resulting in a composite comprising a boron-containing compound and metal. The mass to be infiltrated may contain one or more inert fillers admixed with the boron carbide (12), or at least one carbon donor material, to produce a composite by reactive infiltration, which composite comprises a matrix of metal and boron-containing compound embedding the filler. The relative amounts of reactants and process conditions may be altered or controlled to yield a body containing varying volume percents of ceramic, metal and/or porosity. The mass to be infiltrated can be contained within a refractory vessel (16) having a venting means included therein.
Patent NZ-228071-A (NZ)
Title: Powder inhaler: inbuilt capsule piercing device
Inventor: PEARCE JOHN OLIVER
IPC: A61M15/00
Filed: 1989-02-21
Abstract: A dispenser [10] for powdered medication comprising a housing containing means [50] for piercing a capsule containing powdered medication, a generally cylindrical chamber [30] adapted to receive the capsule and in which the capsule can rotate freely to release the powdered medication, and a mouthpiece [20] through which the powdered medication can be drawn from the chamber [30], in which the chamber has three air inlets [37, 38, 39] spaced around the cylindrical wall of the chamber.
Patent NZ-237739-A (NZ)
Title: Pharmaceutical composition of a complement inhibitor and an immunosuppressant with cyclosporin a-like activity, and its use
Inventor: WHITE DAVID JAMES GRAHAM
IPC: A61K38/13
Filed: 1991-04-08
Abstract: Cyclosporin A, or another compound having cyclosporin A-like activity, and cobra venom factor, or another complement inhibitor, can be used in conjunction with each other to promote allograft and concordant xenograft survival and to rescue such grafts from rejection.
Patent NZ-247738-A (NZ)
Title: Sailboat forestay made of composite fibres impregnated with resin
Inventor: MITCHELL CHRISTOPHER JOHN
IPC: B63B15/02
Filed: 1993-05-31
Abstract: A RACING SAILBOAT FORESTAY COMPRISING FRONT ELEMENT OBTAINED BY PULTRUSION COUPLED WITH A BACK ELEMENT MADE OF POLYMERIC MATERIAL IN WHICH TWO LONGITUDINAL GROOVES ARE PRESENT FOR HOISTING THE SAILS. <IMAGE>
Patent NZ-273569-A (NZ)
Title: Detecting the presence of naphthylamine derivatives in mineral oils by extraction into aqueous medium and treatment with a diazotised aminoanthraquinone
Inventor: DYLLICK-BRENZINGER RAINER
IPC: G01N33/28
Filed: 1994-08-25
Abstract: PCT No. PCT/EP94/02824 Sec. 371 Date Mar. 4, 1996 Sec. 102(e) Date Mar. 4, 1996 PCT Filed Aug. 25, 1994 PCT Pub. No. WO95/07460 PCT Pub. Date Mar. 16, 1995A method for detecting naphthylamines which are present as tracers in mineral oils, wherein the naphthylamine is extracted by treating the mineral oil with an aqueous medium, and is coupled in the aqueous phase with a diazonium salt to form an azo dye, the use of specific naphthylamines as tracers in mineral oils and mineral oils containing these specific naphthylamines.
Patent NZ-286103-A (NZ)
Title: use of pyrrolo-and pyrazolopyrimidine derivatives to treat various neuronal disorders
Inventor: CHEN YUHPYNG L
IPC: A61P25/08
Filed: 1996-03-01
Abstract: The pyrazolo[3,4-d]pyrimidine  or pyrrolo[2,3-d]pyrimidine derivatives of formula I are used in the manufacture of a medicament to treat, prevent or inhibit a disorder selected from head trauma, spinal cord trauma, ischemic neuronal damage, excitotoxic neuronal damage, epilepsy, stroke, stress induced immune dysfunction, muscular spasm, Parkinson's disease, Huntington's disease, urinary incontinence, multi-infarct dementia, amyotrophic lateral sclerosis, chemical dependence and additions and hypoglycemia in mammals. In formula I: X is =N- or =CR6-; A is -NR1R2, -CR1R2R11, -C(=R2R12)R1, -NH-CR1R2R11, -O-CR1R2R11, -S-CR1R2R11, NHN-R1R2, -CR2R11NHR1, -CR2R11OR1, -CR2R11SR1 or -C(O)R2; R1 is H or optionally substituted alkyl, which may contain one or two double or triple bonds; R2 is optionally substituted alkyl, aryl, alkylene-aryl wherein the aryl is phenyl, naphthyl or a heteroaryl as defined in the specification, cycloalkyl or alkylene-cycloalkyl wherein one or two of the carbons of the cycloalkyl can be replaced by O, S or N-Z which may contain one or two double or triple bonds or R1 and R2 together with the atom to which they are attached may form an optionally saturated 3-8 membered ring wherein one or two or the carbons can be replaced by O, S or N-Z; R3 is H, alkyl, F, Cl, Br, I, OH, amino, -O-alkyl, -mono or di-alkylamino, thiol, -S(O)n-alkyl with n being 0 to 2 wherein the alkyl moieties may contain one or two double or triple bonds and may be substituted; R4 is H, alkyl, F, Cl, Br, I, alkoxy, formyl, mono or di-alkylamino, -S(O)n-alkyl with n being 0 to 2, cyano, OH, carboxy or amido wherein the alkyl moieties may be substituted; R5 is optionally substituted phenyl, naphthyl or a heteroaryl as defined in the specification, cycloalkyl or bicycloalkyl wherein one or two of the carbons of the cycloalkyl can be replaced by O, S or N-Z which may contain one or two double or triple bonds; R6 is H, alkyl, F, Cl, Br, I, OH, amino, -alkoxy, formyl, amino, -mono or di-alkylamino, -S(O)n-alkyl with n being 0 to 2, cyano, OH, carboxy or amido wherein the alkyl moieties may contain one or two double or triple bonds and may be substituted; R11 is H, OH, F, Cl, -COO-alkyl, cyano or -CO-alkyl and Z is H, alkyl, alkanoyl, phenyl or benzyl.
Patent NZ-286510-A (NZ)
Title: Method of detoxifying biocide in waste water using a water soluble thio compound
Inventor: WILLIAMS TERRY MICHAEL
IPC: C02F1/54
Filed: 1996-05-03
Abstract: A method of detoxifying biocide which is toxic to aquatic life comprising contacting said biocide with a water soluble organic thiol compound. Applications of the method are primarily for biocide spills or for industrial effluents which comprise biocide and must be detoxified prior to release into the environment, and must pass a photoluminescent bacterial assay. Kits are also disclosed.
Patent NZ-500194-A (NZ)
Title: Broadcasting randomized subscriber entitlement management messages for digital television
Inventor: FICHET LAURENT
IPC: H04N21/442
Filed: 1997-04-18
Abstract: A set of programming messages for a digital broadcasting system (MPEG) is generated as a sequence that is repetitively randomized to form a plurality of sets of the messages, the messages in each set being in random sequence.  The messages are then broadcast to the users, preferably at different rates.  By repetitively randomizing the sequence of entitlement management messages the chance of two messages being broadcast back to back after repetitions can be made negligibly small.  Thus the decoder will not be confused by closely separated entitlement management messages.
Patent NZ-503083-A (NZ)
Title: An aqueous slurry having ceramic fiber, silica sol having a large particle size and broad particle size distribution, and starch is vacuum formed to provide shaped products
Inventor: VANDER MEER JOHN
IPC: D21H13/46
Filed: 1998-09-25
Abstract: A method of vacuum forming of aqueous, fibrous slurries and products produced thereby are described. The method entails forming an aqueous slurry of ceramic fiber, cationic starch and silica sol. The silica has, based on total weight of the sol, about 50% silica having a particle size range of from about 7 nm to about 200 nm and a specific surface area of about 100 m2/gm to about 10 m2/gm. The slurry is passed through a porous screen under a vacuum pressure deposit the solids content onto the screen to produce high strength products.
Patent NZ-503660-A (NZ)
Title: Case rotating mechanism for cosmetic products with hinge elements connecting base to slider
Inventor: DEMELLIER STEPHANE
IPC: A45D40/06
Filed: 1999-07-12
Abstract: Disclosed is a turning case mechanism (1) particularly for cosmetic products, composed of a pivoting body (2) mounted in rotation on a main piece, formed by a traveller (5), base (4) and hinge elements (6) connecting the base to the traveller, between a lower articulation point with the base and an upper articulation point with the traveller; the traveller intended to be mobile between an open or upper position (B) and a closed or lower position, characterised in that when the traveller is in the lower position, the hinge elements are arranged at least in part below the horizontal plane that contains the lower articulation point.
Patent NZ-504703-A (NZ)
Title: Substituted thiazolidinedione derivative, process for its preparation and its pharmaceutical use
Inventor: SASSE MICHAEL JOHN
IPC: A61K31/44
Filed: 1998-12-14
Abstract: A hydrate of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino) ethoxy]benzyl] thiazolidine-2,4-dione,maleic acid salt for use in treating conditions associated with diabetes mellitus, characterized in that it comprises water in the range of from 0.3-0.6molar equivalents; and a process for its preparation.  Such a hydrated form is more suitable for bulk preparation and handling than the previously known anhydrous form.
Patent NZ-504994-A (NZ)
Title: Orally administrable rapidly dissolving solid ribavirin dosage forms
Inventor: LIEBOWITZ STEPHEN M
IPC: A61K9/48
Filed: 1998-12-21
Abstract: Described is an orally administrable solid dosage form containing a compacted ribavirin composition having a high tap density of at least 0.6 g/mL as well as rapid disintegration and dissolution rates.  The ribavirin is substantially free of polymorphic forms of ribavirin.  Also described is a process for making such solid dosage forms.
Patent NZ-505688-A (NZ)
Title: Compressing digital audio files by storing low quality audio file and a second audio properties file
Inventor: VULICH MARCELO HECTOR
IPC: G10L19/02
Filed: 2000-07-11
Abstract: A method for storing digital audio in magnetic memory, from a commercial digital audio product having an identification code on its packing, carried out in a digital audio storage, selection and playback device containing microprocessor based circuit components, an element for inputting identification codes, commercial digital audio product reader and a diskette drive is described. The method comprises a step (a) of converting to computing format and compressing digital audio files by means of a software in a separate equipment, resulting from this conversion and compression a loss of audio properties which result in a loss of audio quality when submitting it to an inverse process of sound playback, further carrying out the steps (b) generation of a digital audio file of audio properties, being function of the selected compression format, and (c) loading of the properties file and the compressed file in at least one element of magnetic memory of the device, being the digital audio properties file able to recover the lost audio properties in simultaneous playback of analog audio of the properties file and the compressed file.
Patent NZ-507742-A (NZ)
Title: HIV-specific cytotoxic T-cell responses
Inventor: SIA CHARLES D Y
IPC: C07K14/16
Filed: 1999-04-01
Abstract: The use of a T-cell inducing HIV derived molecule in a medicine to generate an HIV specific cytotoxic T-cell (CTL) response in a host. The medicine is formulated for separate, sequential or simultaneous administration. The T- helper molecule is selected from the group consisting of DP, DR and DQ-specific t-cell epitopes. The T-helper molecule acts to prime T-helper cells of the immune system of the host before and or during the administration of the medicine.
Patent NZ-510102-A (NZ)
Title: Process and apparatus for making papermaking belt using fluid pressure differential has a reinforced structure joined to a resinous framework
Inventor: AMPULSKI ROBERT S
IPC: B29D29/00
Filed: 1999-09-01
Abstract: A process and an apparatus for making a papermaking belt (90) are provided, the belt comprising a reinforcing structure (40) and a resinous framework (50) joined together. The preferred continuous process comprises the steps of depositing a flowable resinous material onto a patterned molding surface (20); continuously moving the molding surface and the reinforcing structure at a transport velocity such that at least a portion of the reinforcing structure is in a face-to-face relationship with a portion of the molding surface; applying a fluid pressure differential to transfer the flowable resinous material from the molding surface onto the reinforcing structure and causing the flowable resinous material and the reinforcing structure to join together; and solidifying the resinous material thereby forming the resinous framework joined to the reinforcing structure. The apparatus comprises a molding member having a patterned molding surface preferably comprising a plurality of molding pockets to carry a flowable resinous material therein; a means for depositing the flowable resinous material into the molding pockets of the molding surface; a means for moving the reinforcing structure and the molding member in a predetermined direction; and a means for creating a fluid pressure differential sufficient to transfer the flowable resinous material from the molding member to the reinforcing structure.
Patent NZ-510303-A (NZ)
Title: Hydroxamate-containing cysteine and serine protease inhibitors suitable for treatment of neurodegeneration, Alzheimer's, inflammation, cataracts, bone resorption, CNS injury
Inventor: MALLAMO JOHN P
IPC: A61P25/28
Filed: 1999-09-20
Abstract: The compound of formula I wherein: W is A-B-D A is aryl(CH2)n, heteroaryl(CH2)n, alkyl having from 1 to 14 carbons, alkenyl having from 2 to 14 carbons, or cycloalkyl from 3 to 10 carbons. The A group may be optionally substituted with 1 or more J groups. B is a bond or CO, SO, SO2, OCO, NR5CO, NR5SO2 or NR5SO D is a bond, an amino acid residue or a peptide composed of 2 to 5 amino acid residues. The amino acids are independently defined by the formula -NH-**CH(R6)-CO-, in which ** denotes the a carbon of an a-amino acid residue possessing when R6 is other than hydrogen, the D-configuration, the L-configuration or a mixture of D-and L-. n is an integer from 0 to 6 R1, R2, R3, R4, R5 and R6 are independently hydrogen, alkyl having 1 to 14 carbons or cycloalkyl having 3 to 10 carbons. The alkyl and cycloalkyl groups being optionally substituted with 1or more J groups. J is halogen, lower alkyl, aryl, heteroaryl, haloaryl, amino optionally substituted with 1 to 3 aryl or lower alkyl groups, guanidine, alkoxycarbonyl, amido, lower alkylamido, sulfonamido, lower alkyl sulfonamido, lower alkylsulfonyl, lower alkylsulfoxy, lower alkylthio, lower alkoxy, aryloxy, arylalkyloxy, hydroxy, carboxy, cyano or nitro. *denotes the a carbon of an a-amino acid residue possessing when R2 is other than hydrogen, the D-configuration, the L-configuration or a mixture of D-and L- configurations. The compound of formula 1 are useful for neurodegeneration, stroke, Alzheimer's, amytrophy, motor neuron damage, acute central nervous system injury, muscular dystrophy, bone resorption, platelet aggregation, cataracts, inflammation and for inhibiting serine proteases and cysteine protease. Also described are pharmaceutical compositions comprising the compound of formula I.
Patent NZ-515705-A (NZ)
Title: Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor (PPAR) alpha
Inventor: TANASE TAKAHIRO
IPC: C07C235/60
Filed: 2000-06-08
Abstract: Substituted phenyl-propanoic acid derivatives of general formula (1) and processes for their preparation, effective for the therapy of abnormality of lipidmetabolism.  These compounds are agonists of human peroxisome proliferant-activated receptor (PPAR), in particular human PPARá isoform.
Patent NZ-518401-A (NZ)
Title: Dry powder compositions having improved dispersivity
Inventor: LECHUGA-BALLESTEROS DAVID
IPC: A61K38/00
Filed: 2000-04-12
Abstract: The present invention provides a highly dispersible formulation comprising an active agent and a dipeptide or tripeptide comprising at least two leucyl residues. The composition of the invention possesses superior aerosol properties and is thus preferred for aerosolized administration to the lung. Also provided are a method for (i) increasing the dispersibility of an active-agent containing formulation for administration to the lung, and (ii) delivery of the composition to the lungs of a subject.
Patent NZ-522114-A (NZ)
Title: Infusion packet with useful and decorative elements, support member, delivery system and method
Inventor: STILLMAN SUZANNE JAFFE
IPC: A23L33/00
Filed: 2001-03-21
Abstract: A system allowing the tea bag/infusion packet (14) to dispense health enhancing agents and promote the sale and use of safe and health enhancing beverages. The basic packet (14) is a permeable sac containing soluble ingredients tethered to a tag (16). In one embodiment soluble dietary fiber, nutraceuticals, enzymes, and other health promoting ingredients are dispensed. In one embodiment the tag (16) forms part of a game, acts as a prize, or toy, or otherwise promotes the sale and use of the product. In one embodiment the packet (14) is modified to change color or reveal indicia upon contact with water. An additional support member may be supplied to hold or join the infusion packets (14) and may act as a toy, or prize, or game piece. For use in bottles, such as water bottles, a version is provided with features to prevent accidental ingestion of the infusion packet (14).
Patent NZ-522788-A (NZ)
Title: Prolonged therapeutic effect of mixtures of C16 and C18 phospholipid derivatives of valproic acid (DP-VPA) in anti-convulsant medicaments
Inventor: KOZAK ALEXANDER
IPC: A61K31/352
Filed: 2001-07-10
Abstract: Compounds are described, which are phospholipid derivatives of valproic acid, and compositions comprising such compounds and their use for treating epilepsy, migraine, bipolar disorders and pain. The graph depicts a typical HPLC chromatogram of a C16/Cl8-DP-VPA composition, where the C16-DP-VPA to Cl8-DP-VPA ratio is 15%: 85%, by weight.
Patent NZ-524509-A (NZ)
Title: A graphical management interface for radio stations
Inventor: HOOKER GUY ALEXANDER
IPC: G06F17/24
Filed: 2003-03-03
Abstract: A graphical management interface for a radio station includes a display region (main screen display) for presenting programmed functions of the station, an input control (in the Task List Item frame) for user selection of input conditions to form programmed functions and a second output control (in the Task List Item frame) for user selection of output actions to be carried out by the station in response to the input condition. A control (such as the set of command or menu buttons down the right hand side of the interface) for user editing of the functions is also provided.
Patent NZ-529283-A (NZ)
Title: Building structure and modular construction method
Inventor: BERGQVIST TONNY ERNST
IPC: E04D3/35
Filed: 2001-05-30
Abstract: A building structure comprising one or more modular panels (5); a wall locating member (12) positioned between a base (2) and the one or more modular panels (5); a top member (19) placed on top of the modular panels (5); and a plurality of tie rods (14). The modular panels (5) when adjoining to form a wall create longitudinal cavities (16) within the wall. The plurality of tie rods (14) extend through said longitudinal cavities (16) and secure said top member (19), walls (3) and wall locating member (12) to the base (2).
Patent NZ-530295-A (NZ)
Title: Storage device for shaving razor, cartridges, or other stored items
Inventor: WORRICK CHARLES BRIDGHAM III
IPC: B65D43/16
Filed: 2000-07-24
Abstract: A wall-mounted storage device for connection to a securing device that is securely mounted to a wall and carries first engagement structure, the storage device including a base member that is removably mounted to the securing device, the base member carrying second engagement structure that removably engages the first engagement structure wherein the base member has a plurality of package-receiving storage regions, one or more packages that are each located in a respective region, each package containing a single razor cartridge comprising a plastic housing and one or more blades, and each of the plurality of compartments has a major longitudinal axis arranged transverse to a vertical axis of storage device mounted to a wall, the major longitudinal axes of each package and razor cartridge contained therein being disposed substantially parallel to the region longitudinal axis. (62) Divided out of 516629