Patent CA-3079724-A1 (CA)
Inventor: LOVEJOY DAVID
IPC: A61K38/17
Filed: 2018-10-12
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY  (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date                   WO 2019/075416 Al 18 April 2019 (18.04.2019)        WIPO I PCT (51) International Patent Classification:                                           (81) Designated States (unless otherwise indicated, for every A61K 38/17 (2006.01)     A 61P 25/22 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (21) International Application Number: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (22) International Filing Date:                                                     HR, HU, ED, EL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, 12 October 2018 (12.10.2018)             KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (25) Filing Language:                     English OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (26) Publication Language:                English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 62/571,616         12 October 201'7 (12.10.201'7) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (72) Inventors; and GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (71) Applicants: LOVEJOY, David [CA/CA]; 149 Baker    UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, St., Stouffyille, ON ON L4A1K6 (CA). STEIN, Robert    TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, [US/US]; '7 Peter Cooper Road, Apt. 10b, New York, NY    EE, ES, FI, FR, GB, GR, HR, HU, EE, IS, IT, LT, LU, LV, 10010 (US). SLEE, Andrew [GB/US]; 23 Camelot Drive,    MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, Shrewsbury, MA 01545 (US). ARMEN, Garo [US/US];    TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, 447 West 18th Street, Unit Gd4, New York, NY 10011    KM, ML, MR, NE, SN, TD, TG). (US). (74) Agent: PURSLEY, Kristen, L. et al.; The Dobrusin Law Published: Firm, PC, 29 W. Lawrence Street, Suite 210, Pontiac, MI ¨ with international search report (Art. 21(3)) 48342 (US).                                                                     ¨ with sequence listing part of description (Rule 5.2(a)) = (54) Title: COMPOSITIONS, METHODS AND USES FOR TREATING POST-TRAUMATIC  STRESS DISORDER Figure 1 38                       Mouse TCAP 1 (41) Gln Gln Leu Leu obi Thr Gly Arg Val Gin Gly Tyr Asp Gly Tyr Phe Val Lau Ser Val Glu Gin Tyr Leu Giu Leu Ser Asp Ser Ala Asn Asn Ile His Phe Met Arg Gin Ser Glu Ile(SEQ. ID. NO. 'I) 70                       Human TCAP 1 (41) Gln Gln Lau Leu                     Thr Gly Arg Val Gin Giy Tyr Asp Gly Tyr Phe Val Leu Sef Val Glu Gin Tyr Leu Glu Leu Ser Asp Ser Ala Asn Asn ile His Phe Met Arg Gin Ser Glu ile (SEQ. ID. NO. 2) 101                      G. Gallus TCAP-1 (41) Gln Gln Leu Leu                     Tbr Gly Arg Val Gin Gly Tyr Asp Gty Tyr Phe Val Leu Ser Val Glu Gin Tyr Leu Glu Leu Ser Asp Ser Ala Asn Asn Nre                      ile His Phe Met Arg Gin Ser Glu Ile (SEQ. ID. NO. 3) (57) Abstract: The present matter relates to compositions comprising a Teneurin C-terminal Associated Peptide - 1 (TCAP-1) peptide C and methods and uses of same for preventing and/or treating post-traumatic stress disorder ("PTSD").