baber/WOPTO huggingface dataset:
Patent GB-8808433-D0 (GB)
Title: Therapeutic agents
IPC: C07D498/10
Filed: 1988-04-11
Abstract: The present invention provides a compound of formula I or a salt or prodrug thereof: <CHEM> wherein the dotted line represents an optional chemical bond in one of the two possible positions;  A represents a group of formula II: <CHEM> in which R<1> represents hydrogen, hydroxy, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxy, benzyloxy, hydroxy(C1-6)alkyl, halogen, amino, cyano, nitro, -CONR<6>R<7> or -SO2NR<6>R<7>, in which R<6> and R<7> independently represent hydrogen, C1-6 alkyl, C2-6 alkenyl or C2-6 alkynyl; R<2> represents hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy or C1-6 alkylcarbonyl;  V represents nitrogen, -CH or -C-; and W represents oxygen, sulphur or -NR<8>, in which R<8> represents hydrogen, C1-6 alkyl, C2-6 alkenyl or C2-6 alkynyl; two of X, Y and Z are the same or different and each represents oxygen, sulphur or nitrogen; and the remaining group X, Y or Z is carbon, or Y is carbonyl (C=O); and Q is the residue of an azacyclic or azabicyclic ring system; which compounds are useful in the treatment of psychotic disorders (e.g. schizophrenia and mania); anxiety; alcohol or drug withdrawal or,dependence; pain; gastric stasis; gastric dysfunction (such as occurs with dyspepsia, peptic ulcer, reflux oesophagitis and flatulence); migraine, nausea and vomiting; moyement disorders; and presenile and senile dementia,
Patent GB-8809616-D0 (GB)
Title: Further improvements relating to drug delivery systems
IPC: C07K16/40
Filed: 1988-04-22
Abstract: The invention provides A conjugate comprising (a) an antibody selected from antibody A5B7 and antibody SB10; linked to (b) an enzyme selected from carboxypeptidase G2 (CPG2) and nitroreductase. The invention can be used in a system which comprises i) a humanised antibody to tumour associated antigen linked to a member of the group consisting of a human enzyme, a non-human enzyme rendered non-immunogenic in man and a humanised catalytic antibody and ii) a prodrug convertible under the influence of i) into a cytotoxic drug.
Patent GB-9127505-D0 (GB)
Title: Multi-hole film cooled afterburner combustor liner
IPC: F23R3/00
Filed: 1991-12-31
Abstract: The present invention provides a cooling apparatus with two spaced apart walls, one of which is a coolable wall, having a cooling flowpath between them wherein the cooling flowpath is converging in the direction of the cooling flow. In one embodiment the coolable wall is an afterburner cooling liner that includes a film cooling means on the hot side of the liner. Another embodiment provides a corrugated or wavy wall afterburner cooling liner wherein each wave includes a forward facing surface, from crest to trough of the wave in the direction of the hot gas flow, and an aft facing surface, from trough to crest. A high density pattern of multi-hole film cooling holes is disposed on the hotter of the two surfaces and a lower density pattern on the cooler one.
Patent GB-9201863-D0 (GB)
Title: Multi glazing air cushion release unit
IPC: A62B3/00
Filed: 1992-01-29
Abstract: PCT No. PCT/GB93/00168 Sec. 371 Date Dec. 20, 1994 Sec. 102(e) Date Dec. 20, 1994 PCT Filed Jan. 27, 1993 PCT Pub. No. WO93/15297 PCT Pub. Date Aug. 5, 1993A release device for an air cushion or thermal insulation barrier of a double or multi glazed glass unit comprises interfitting first and second members which are movable relative to one another, the first member having associated with it a pin or striker which is movable with the first member from an inoperative position to an operative position to crack or penetrate one or more glass panels of the unit, the device has one or more ventilation orifices to enable release of the sealed air cushion or thermal insulation barrier between the panes of a glazed unit. To limit the relative movement of the first and second members of the device there is within the device interfitting projections. The device, which may include one or more springs, may be mounted on a support structure for movement from an inoperative position to an operative position.
Patent GB-9222561-D0 (GB)
Title: Macromolecular degradation
IPC: C12P7/62
Filed: 1992-10-27
Abstract: PCT No. PCT/GB93/02208 Sec. 371 Date Apr. 27, 1995 Sec. 102(e) Date Apr. 27, 1995 PCT Filed Oct. 27, 1993 PCT Pub. No. WO94/10289 PCT Pub. Date May 11, 1994Peroxide, particularly supplied as hydrogen peroxide, is an effective nucleic acid degrading agent and can be used in the recovery of intracellularly produced materials from cell (particularly bacterial) lysates. The degradation or removal of nucleic acids from cell lysates is important because they form solutions of high viscosity which interfere with subsequent processing. Peroxide degradation is particularly useful in the recovery of polyhydroxyalkanoate polymers such as polyhydroxybutyrate/valerate from lysates of bacterial cells in which they are produced.
Patent GB-9302046-D0 (GB)
Title: Antiumoral compound-v
IPC: A61K36/02
Filed: 1993-02-03
Abstract: Kalahide F, of formula I below, may be isolated from a sacoglossan. The compound may be used in the manufacture of pharmaceutical compositions or in the treatment of tumors or viral conditions. <CHEM>
Patent GB-9307523-D0 (GB)
Title: Detection of cns gases
IPC: G01N33/53
Filed: 1993-04-13
Abstract: PCT No. PCT/GB94/00766 Sec. 371 Date Dec. 1, 1995 Sec. 102(e) Date Dec. 1, 1995 PCT Filed Apr. 12, 1994 PCT Pub. No. WO92/24554 PCT Pub. Date Oct. 27, 1994Techniques for the detection of disease of the central nervous system, particularly of bovine spongiform encephalopathy or "mad cow disease", scrapie and related states, are provided based upon the detection of a factor present in the urine of affected animals or humans. That factor is defined in terms of elution data from an ion exchange column and by electrochemical characteristics.
Patent GB-9415050-D0 (GB)
Title: Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
IPC: C07F15/02
Filed: 1993-12-06
Abstract: The invention provides antioxidant salen-metal complexes in a form suitable for pharmaceutical administration to treat or prevent a disease associated with cell or tissue damage produced by free radicals such as superoxide.
Patent GB-9602731-D0 (GB)
Title: Transmission control systems
IPC: F16H59/14
Filed: 1996-02-10
Abstract: A vehicle transmission control system in which a central control unit (36) issues signals to an associated main drive clutch actuator (22,38) and to ratio actuating means (25) to effect changes in the operative ratio of an associated transmission (12) in accordance with a predetermined shift point map. When the shift point map indicates that the ratio shift is appropriate, the system tests for fluctuations in the position of an associated engine accelerator pedal (19) and only actions the shift if the degree of fluctuation of the accelerator pedal position is judged acceptable. The acceptable level of accelerator pedal fluctuation preferably varies with engine speed. <IMAGE>
Patent HU-0001249-D0 (HU)
Title: Novel substituted dimeric compounds, process for their production and medicaments containing the same
Inventor: BENNEJEAN CAROLINE
IPC: A61K31/33
Filed: 2000-03-24
Abstract: Compounds (I) selected from alkylenedioxybisnaphthalene derivatives and related compounds are new.  Compounds of formula (I) other than diethyl 2-acetylamino-2-(5-(3-(2-acetylamino-3-ethoxy-2-ethoxycarbonyl-3-oxopr opyl)-1H-indol-5-ylmethyl)-1H-indol-3-ylmethyl)malonate and N-(2-(5-(3-(2-acetylaminoethyl)-1H-indol-5-ylmethyl)-1H-indol-3-yl)eth yl)acetamide are new.  A = NR<1>-C(Q)-R<2>, NR<1>-C(Q)-NR<2>R<3> or C(Q)-NR<2>R<3>;  Q = O or S;  R<1> - R<3> = H or R; or  NR<2>R<3> = 1-piperazinyl, piperidino or pyrrolidino;  R = optionally Q'-substituted 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, 3-8C cycloalkyl or (3-8C cycloalkyl)-(1-6C alkyl); 1-6C polyhaloalkyl; or optionally Q-substituted aryl, aryl(1-6C alkyl), aryl(2-6C alkenyl), heteroaryl, heteroaryl-(1-6C alkyl) or heteroaryl-(2-6C alkenyl);  B = NR<1>-C(Q)-R<2>, NR<1>-C(Q)-NR<2>R<3>, C(Q)-NR<2>R<3>, C(Q)-OR<1>, NR<1>-C(Q)-OR<2> or NR<2>R<3>;  G1, G3 = 1-4C alkylene optionally substituted by one or more of OH, COOH, CHO, R, OR, C(O)OR or C(O)R; Cy = a group of formula (i) in which G2 is attached to the benzene ring and G1 or G3 is attached to the other ring, or a group of formula (ii) in which G2 is attached to the D ring and G1 or G3 is attached to the other ring:  X, Y' = S, O, C, CH or CH2;  R<4> = H, halogen, CF3, OH, COOH, CHO, NH2, NHR, NRR', NHC(O)R, C(O)NHR, R, OR, C(O)R or COOR;  R' = R;  Z' = S, O, CH, CH2, NH, NSO2-phenyl or NR; D' = a benzene or pyridine ring;  G2 = an optionally substituted W1(CH2)nW2(CH2)mW3 group containing no adjacent heteroatoms;  W1-W3 = bond, O, S, CH2, CHR, NH or NR;  n, m = 0 - 6;  Q' = one or more of OH, 1-6C alkoxy, 1-6C polyhaloalkyl, NH2, 1-6C alkylamino, di(1-6C alkyl)amino and halogen;  aryl = naphthyl, phenyl or biphenylyl; heteroaryl = a saturated or unsaturated mono- or bicyclic group containing 5-10 C atoms and 1-3 heteroatoms selected from N, S and O; and  Q = OH, COOH, 1-6C alkoxy, 1-6C alkyl, 1-6C polyhaloalkyl, CHO, CN, NO2, NH2, 1-6C alkylamino, di(1-6C alkyl)amino and halogen. Independent claims are also included for the following:  (1) a process for preparing (I); and  (2) compounds of formula (II) other than N-(2-(5-(2-hydroxyethoxy)-1H-indol-3-yl)ethyl)acetamide.  W4 = O, S, NH or NR; and  E' = OH or halogen;  provided that W4-(CH2)n-W2-(CH2)m is not oxyalkylene when Cy is naphthylene and G1-A is (CH2)2-NR<1>CQR<2> or (CH2)2-NR<1>CQNR<2>R<3>.
Patent HU-9201165-D0 (HU)
Title: Method and device for testing mechanical features of coins
Inventor: ECHAPARE IBARRO JESUS
IPC: G07D5/04
Filed: 1992-04-07
Abstract: Device for obtaining mechanical characteristics of coins, comprised of an element which is elastically deformable by the weight of coins during their passage on said element. The deformation of said element will depend on the weight of the coins and their position on the length of said element. The elastically deformable element is provided with sensors in order to obtain an electric signal inherent to the mechanical characteristic searched in the coin. From the impact produced by the drop of the coins on said beam a parameter representative of the mechanical elasticity of the coin is determined by means of frequency analysis, by proceeding to the measurement of higher harmonics of the impact signal. <IMAGE>
Patent HU-9300506-D0 (HU)
Title: Method for obtaining sennoside a, b as well as a1
Inventor: CARCASONA ALFONS
IPC: A61K31/70
Filed: 1992-06-24
Abstract: The invention concerns a method of extracting sennosides A, B and A1. The method comprises the following steps: a sennoside mixture is reduced to the corresponding anthrone-8-glucosides, the aloe-emodin components are removed by liquid-liquid separation of the anthrone-8-glucosides, and the rheine-9-anthrone-8-glucoside obtained after the separation step is oxidized again to sennosides A, B and A1. The invention also concerns sennosides A, B and A1 obtained by this method and pharmaceutical agents containing them.
Patent HU-9302437-D0 (HU)
Title: Treatment of cellulitis with retinoides
Inventor: KLIGMAN ALBERT A
IPC: A61K31/19
Filed: 1992-02-26
Abstract: A method for retarding and reversing cellulite comprises topically applying to human skin a retinoid in an amount and for a period of time effective to retard or reverse cellulite where said amount is insufficient to be excessively irritating. The method preferably uses retinoic acid in an emollient vehicle.
Patent HU-9503780-D0 (HU)
Title: Titanium(ii) or zirconium(ii) complexes and addition polymerization catalysts therefrom
Inventor: TIMMERS FRANCIS J
IPC: C07F/
Filed: 1994-06-16
Abstract: Novel catalytic derivatives of titanium or zirconium complexes containing one and only one cyclic delocalized, anionic, +529 -bonded group wherein the metal is in the +2 formal oxidation state and having a bridged ligand structure and an activating cocatalyst are useful as catalysts for polymerizing olefins, diolefins and/or acetylenically unsaturated monomers.
Patent HU-9601659-D0 (HU)
Title: 6-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists
Inventor: CUPPS THOMAS LEE
IPC: A61P27/02
Filed: 1994-12-15
Abstract: The subject invention relates to compounds having the structure:   <IMAGE>   wherein: (a) R is unsubstituted C1-C3 alkanyl or alkenyl; (b) R' is selected from unsubstituted C114 C3 alkanyl or alkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thiol; and halo; and (c) R'' is selected from hydrogen; unsubstituted C1-C3 alkanyl or alkenyl; methyl monosubstituted with hydroxy, thiol or amino; unsubstituted C1-C3 alkylthio or alkoxy; amino; unsubstituted amide; unsubstituted or C1-C3 substituted amido; halo; unsubstituted sulfoxide; unsubstituted sulfonyl; and cyano; pharmaceutical compositions containing such compounds, and the use of such compounds for preventing or treating respiratory, ocular, and/or gastrointestinal disorders.
Patent IT-8021271-D0 (IT)
Inventor: MASSIMO CALANCHI
IPC: B01J13/02
Filed: 1980-04-09
Abstract: The invention relates to a process for preparing microcapsules in a liquid vehicle, allowing to microencapsulate both water soluble and water insoluble substances, using either ionic or non-ionic systems, in which the membrane enclosing the core of the microcapsules is formed by a polymer selected from the group of the phthalates, and more particularly by hydroxypropylmethylcellulose phthalate.
Patent IT-8422258-D0 (IT)
Inventor: MORA CAMILLO CORVI
IPC: C07C29/48
Filed: 1984-08-08
Abstract: A novel derivative of (―)-6,6-dimethylbicyclo [3.3.1]ept-2-ene-2-methanol is disclosed.The compound of formula (I), which is an object of the present invention, is the derivative :a,a-dimethyl-5-hydroxy-3-cyclohexene-1,4-dimethanol.The present invention further discloses the process for obtaining the compound of formula (I), which consists in preparing the (-)-6,6-dimethylbicyclo [3.3.1]ept-2-ene-2- methanol epoxide, thereafter hydrating the above compound and separating the compound of formula (I) from the hydration products. Finally, this invention comprises the pharmaceutical compositions containing the compound of formula (I) which possess a pharmacological mucosecretolytic activity.
Patent IT-8622582-D0 (IT)
Inventor: BORDIGNON ABRANO
IPC: G11B23/087
Filed: 1986-12-04
Abstract: The present application relates to a liner for magnetic tape cassettes comprising a sheet-like element (1) insertable between the axial ends of the reels (6) of magnetic tape and the inner walls of the box-like shell (5) of the cassette (4) and defining a pair of through holes (2) located at the hubs (3) of said reels (6). The sheet-like element (1) defines at least one centering ridge (10) with high elastic rigidity which engages at least partially with the peripheral region of the axial ends of said hubs (3), for centering of the hubs with respect to the middle plane of the cassette (4), and at least one alignment ridge with very low elastic rigidity engageable with the longitudinal edges of the magnetic tape, for aligning the windings of the reel of magnetic tape (6).
Patent IT-8723296-D0 (IT)
Inventor: GHIARDO FIORENZO
IPC: D03D51/34
Filed: 1987-12-31
Abstract: Device (2) for feeling and detecting weft yarn breakage (weft-feeler), of the type applied upstream of weft feeders (3) (between the weft yarn spools and the weft feeder) in the weft supply of shuttleless looms, in order to stop the loom (5) in due time in case of weft yarn breakage to prevent the insertion of broken or faulty wefts, the loom stopping signal (SP1) being sent from said device after a certain delay time T has elapsed from the moment in which the weft yarn breakage has been detected while the weft feeder is in operating conditions. In said weft-feeler, the delay time is automatically adjusted by an electronic circuit (23) of the weft-feeler, in relation to the momentary speed of the weft feeder motor.
Patent IT-9047823-D0 (IT)
Inventor: GRANDORI CARLO
IPC: E21D9/087
Filed: 1990-04-02
Abstract: The invention relates to a boring machine for digging tunnels in a wide variety of qualities of ground, of the type comprising a first front shield (1), containing the boring head (15), and the members for driving the same, and a second shield (2), fitted with posts or "grippers" (4)for providing the anchorage necessary for the advancement of the boring machine, in which a third shield (3) is provided, arranged between said first and said second shield, such that the first shield overlaps partly with it and is able to slide axially with respect to the third shield itself and that the assembly first shield/third shield is able to vary its advancing direction with respect to the second shield; guide means (8) being provided between saidffirst and said third shield, which guide means allow these latter to perform a relative movement in the longitudinal axial direction only, and means (5) being provided for advancing said first shield with respect to said third sh shield, as well as means (10) for setting at an angle the assembly first shield/third shield with respect to said second shield. <IMAGE>
Patent IT-7868381-D0 (IT)
IPC: F28D9/00
Filed: 1978-06-14
Abstract: A plate heat exchanger for cooling lubricating oil in internal combustion engines comprises a plurality of superimposed, spaced- apart flattened conduits 2 each formed by two superimposed plates 7 and 8 welded together around their edges, each conduit having, in each plate thereof, an inlet and an outlet opening, the inlet openings together defining, in the heat exchanger an inlet duct and the output openings together defining an outlet duct. Each plate 7 or 8 has extending from the rim of at least one of its openings a respective attachment member 14, in the form of an integral tubular member having notches 15 therearound defining lugs 16 between the notches. Each attachment member 14 extends to within the attachment member of an adjoining conduit 2 and is welded to the last mentioned attachment member. <IMAGE>
Patent SE-0000333-D0 (SE)
Inventor: FLORANDER NILS-AAKE
IPC: B63H25/38
Filed: 2000-02-02
Abstract: Boat propeller drive unit with an underwater housing (5), which is solidly joined to a boat hull and has pulling propellers (15, 16) on the forward facing side of the housing. At the aft edge of the underwater housing, a rudder is mounted, comprising a first rudder blade (22a) mounted in the underwater housing and a second rudder blade (22c) mounted on the aft edge of the first rudder blade.
Patent SE-0000846-D0 (SE)
Inventor: POTTHOFF KLAUS
IPC: F16K31/46
Filed: 2000-03-15
Abstract: The present invention relates to an apparatus (1) for tapping of water, which comprises a valve device (4) with an inlet (19), connected to a water source, as well as an outlet (21) and a seat (29), positioned there between and actuated by spring-loaded shut off and opening means (26, 35). The valve device (4) comprises according to the invention two cup-shaped halves (10; 11), facing each other, between which by means of an edge area all around a rubber elastic membrane (35) is fastened, which separates the hollow spaces (34; 37) of the two halves from each other, which membrane within one of the hollow spaces (37) abuts said seat (29), which inwardly limits the inlet opening (16) of the inlet (19), and which membrane within the other hollow space (34) is actuated by means of said shut off and opening means, designed as a valve plate (26), which presses the membrane against the seat (29), which plate is influenced by said spring actuation and extends through the corresponding body half (11) with a spindle (25), to which drawing means (5-8; 30) are connected for a temporary pressure relief of the membrane within the seat area and consequently also a discharge of the medium flow into the respective hollow space (37) and out of the outlet (21).
Patent SE-0100858-D0 (SE)
Inventor: CHIQUEST ANDRE
IPC: B65B51/22
Filed: 2001-03-12
Abstract: Packaging laminate (10) for a packaging container, which packaging laminate comprises a structural base layer (4), and an inside layer (6). According to the invention, said inside layer (6) comprises a sealing ply (2) of a heat sealable thermoplastic material, which sealing ply is arranged to be the outermost layer on one side of the laminate (10), intended to be arranged on the inside of said container, said heat sealable thermoplastic material exhibiting a melt enthalply lower than 115 J/g. The invention also relates to a method of producing packaging containers from the packaging laminate, and to a packaging container produced from the packaging laminate.
Patent SE-0101811-D0 (SE)
Inventor: REUM KLAUS
IPC: B65B35/18
Filed: 2001-05-22
Abstract: A device (10) for supplying blister strips (6) from a stamping instrument (15) onto the conveyor belt (40) of a cartoning machine consists of a base station (11) and a grouping station (13) connected to the base station (11). In the base station (11) there are arranged suction rotors (17) for depositing the stamped-out blister strips (6) onto a blister-transport belt (20) and also replenishing shafts (28) and segregating shafts (24). In the event of an increase in the number of blister strips (6) arranged side by side in the blister strand (5) replenishing shaft (33) and segregating shaft (36), in the region of the grouping station (13), interact with an additional track (27) of transport belt (20) for replacing defective blister strips (6) on track (27). Tracks (25-27) of transport belt (20) may each have a separate drive unit. Strips (6) are preferably transferred from belt (20) to the cartooning machine by a push-across rotor (38).
Patent SE-0102416-D0 (SE)
Inventor: OEGREN JONAS
IPC: H02J7/00
Filed: 2001-07-05
Abstract: The present invention relates to a battery charger (1) for a mobile unit (2) adapted to charge a chargeable battery (21) belonging to the mobile unit (2). The mobile unit (2) includes a first computer unit (22) and a first memory (23) in which information can be stored. The battery charger ( 1) is adapted to co-act with a memory handling unit (3) upon contact with a mobile unit (2). The memory handling unit (3) includes a second memory (32) and is adapted to read the contents of the first memory (23) belonging to the mobile unit (2) and to store said contents in the second memory (32) and to give the mobile unit (2) access to the contents of the second memory (32).
Patent SE-0104204-D0 (SE)
Inventor: JACOBSSON ROLF ALEXIS
IPC: F02C6/08
Filed: 2001-12-14
Abstract: A compressor unit intended for delivering a pressurised gaseous medium at a varying outlet flow volume to a consumer with varying load demands and comprises one or more rotors (K; 10, 11 ) forming one or more compressor stages and arranged to operate continuously at high speed thereby delivering a certain outlet flow volume, a drive motor (M; 19 ), a drive line assembly (N; 17, 18 ) mechanically coupling the compressor rotor or rotors (K; 10, 11 ) to the drive motor (M; 19 ), and a waste flow circuit connected to the outlet end of the compressor stages and incorporating at least one power recovery turbine (T<SUB>R</SUB> ; 22, 23 ) mechanically coupled to the drive line assembly (N; 17, 18 ), and one or more valves (V; 25, 34, 35 ) controlling the waste flow through the waste flow circuit in response to the actual load demand, wherein the power recovery turbine or turbines (T<SUB>R</SUB> ; 22, 23 ) are arranged to deliver power back to the drive line or drive lines (N; 17, 18 ) at consumer load demands smaller than the certain outlet flow volume delivered by the compressor rotor or rotors (K; 10, 11 ).