baber/WOPTO huggingface dataset:
Patent AU-4986797-A (AU)
Title: Monocyclic l-nucleosides, analogs and uses thereof
Inventor: RAMASAMY KANDASAMY
IPC: A61K31/70
Filed: 1997-10-15
Abstract: Novel monocyclic L-Nucleoside compounds have the general formula  Embodiments of these compounds are contemplated to be useful in treating a wide variety of diseases including infections, infestations, neoplasms, and autoimmune diseases. Viewed in terms of mechanism, embodiments of the novel compounds show immunomodulatory activity, and are expected to be useful in modulating the cytokine pattern, including modulation of Th1 and Th2 response.
Patent AU-5150800-A (AU)
Title: High throughput functional genomics
Inventor: HICKMAN JAMES J
IPC: G01N33/483
Filed: 2000-05-22
Abstract: The system of the invention analyzes <i>how</i> the action potential is interrupted by drugs or toxins. Differences in the action potentials are due to individual toxins acting on different biochemical pathways, which in turn affects different ion channels, thereby changing the peak shape of the action potential differently for each toxin. Algorithms to analyze the action potential peak shape differences are used to indicate the pathway(s) affected by the presence of a new drug or compound; from that, aspects of its function in that cell are deduced. This observation can be exploited to determine the functional category of biochemical action of an unknown compound. An important aspect of the invention is surface chemistry that permits establishment of a high impedance seal between cell and a metal microelectrode. This seal recreates the interface that enables functional patch-clamp electrophysiology with glass micropipettes, and allows extracellular electrophysiology on a microelectrode array.
Patent AU-5194598-A (AU)
Title: (streptococcus pneumoniae) antigens and vaccines
Inventor: KUNSCH CHARLES A
IPC: C12N15/31
Filed: 1997-10-30
Abstract: The present invention relates to novel vaccines for the prevention or attenuation of infection by  Streptococcus pneumoniae.  The invention further relates to isolated nucleic acid molecules encoding antigenic polypeptides of  Streptococcus pneumoniae.  Antigenic polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention additionally relates to diagnostic methods for detecting  Streptococcus  nucleic acids, polypeptides and antibodies in a biological sample.
Patent AU-5198390-A (AU)
Title: Novel vitamin d analogues
Inventor: CALVERLEY MARTIN JOHN
IPC: A61P3/08
Filed: 1990-02-13
Abstract: The present invention relates to compounds of formula (I), in which formula R stands for an alkyl group containing from 7 to 12 carbon atoms optionally substituted with a hydroxy group; and derivatives of the compounds of formula (I) in which one or more hydroxy groups have been transformed into -O-acyl or -O-glycosyl or phosphate ester groups, such masked groups being hydrolyzable in vivo, in pure form or in mixtures. The present compounds find use in both the human and veterinary practice in the treatment and prophylaxis of autoimmune diseases, including diabetes mellitus, hypertension, inflammatory diseases such as rheumatoid arthritis and asthma as well as diseases characterized by abnormal cell differentiation and/or cell proliferation, and/or imbalance in the immune system.
Patent AU-5245379-A (AU)
Title: Pyrimido (6,1-a)isoquinolin-4-ones
Inventor: LAL BANSI
IPC: A61K31/675
Filed: 1979-11-02
Abstract: What are disclosed are compounds of the formula   <IMAGE>   wherein, X is oxygen, sulfur, or halogen, useful as intermediates in the preparation of certain pyrimido(6,1-a)isoquinolin-4-ones having pharmaceutical utilities, and methods for making said intermediates.
Patent AU-5543690-A (AU)
Title: Bit error rate detection
Inventor: FREEBURG THOMAS A
IPC: H04L1/20
Filed: 1990-04-23
Abstract: There is provided a scheme for bit error rate detection. It is characterised by: detecting the bit value present in a received multi-level signal (102), more narrowly detecting the bit value present in that received multi-level signal (104), comparing the results of narrow detection with the results detected otherwise to identify errors in detection (203, 206, 207 and 209), and accumulating detected symbol errors over unit time. Bit error rate detection can be used for antenna selection-selecting one of a plurality of diversity antennas when the error rate exceeds (213) a certain error threshold.
Patent AU-5628596-A (AU)
Title: Novel dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof
Inventor: KATO RYOHEI
IPC: C07D207/16
Filed: 1996-06-28
Abstract: The present invention provides a novel dipeptide compound or pharmaceutically acceptable salt thereof which exhibits an excellent HIV protease inhibitory activity and an excellent bioavailability from digestive tracts, and an anti-AIDS agent comprising said dipeptide compound as an effective ingredient. <CHEM> (wherein R1 represents 5-membered or 6-membered monocyclic hydrocarbon group or heterocyclic group wherein more than one carbon atom of said monocyclic hydrocarbon group is substituted with hetero atom. X represents methylene group (-CH2-), chloromethylene group(-CH(Cl)-), oxygen atom sulfur atom or sulfonyl group (-SO2-). R21 and R22 each represents hydrogen atom or aliphatic hydrocarbon group having 1-6 carbons. R3 represents aliphatic hydrocarbon group or monovalent group derived from aromatic monocyclic hydrocarbon having 1-6 carbons.)
Patent AU-5759596-A (AU)
Title: Test device for use in processing machines
Inventor: PUTTKAMMER FRANK
IPC: G07D7/16
Filed: 1996-05-10
Abstract: PCT No. PCT/DE96/00874 Sec. 371 Date Mar. 2, 1998 Sec. 102(e) Date Mar. 2, 1998 PCT Filed May 10, 1996 PCT Pub. No. WO96/36019 PCT Pub. Date Nov. 14, 1996In accordance with the invention, a multi-compact-sensor is provided with a sensor support for receiving different and exchangeable sensors, brackets and supports for assembly into existing and/or new processing machines at a ascending angle, a board which contains the evaluation circuitry and elements for connection with the sensors as well as, depending on intended use and objects to be tested, an exchangeable cover. The combining of a plurality of individual components, the inventive exchangeability of different sensors, the versatility of the possibilities of use and the handling of the sensors and evaluation electronics into a component of compact structure justify calling the inventive device a multi-compact-sensor.
Patent AU-5850899-A (AU)
Title: A method of metallizing the surface of a solid polymer substrate and the product obtained
Inventor: GLEJBOL KRISTIAN
IPC: C23C18/54
Filed: 1999-10-04
Abstract: A method of metallizing a solid polymer substrate comprising the steps of: a) generating radicals on the substrate surface by subjecting it to a gas plasma, b) forming a layer on the surface using a plasma enhanced polymerisation process employing one or more monomers comprising monomers selected among cyano acrylate, mono- and diacrylates, such as acrylic acid, triethylen glycol diacrylate, glycidyl acrylate, isocyanates, such as 1,4-diisocyanobutane, toluenediisocyanate, epoxy compounds, such as glycidyl methacrylate, preferably 2,3-epoxypropyl methacrylate, allylic and vinylic compounds, such as vinyl acetic acid, vinyl norbonene, vinyl pyrrolidone, vinyl trimethoxysilane, vinyl trimethylsilane allylene, allylalcohol, allyloxymethylsilane, allylphenol, allylurea 1-allyltheourea(thiosineamine), c) providing a short surface deposition using a PVD or CVD process to deposit metal atoms, such as copper, tin, silver palladium, platinum, or gold, and d) optionally providing a metallization of the surface by using a conventional electroless bath, or avoiding electroless metallization by using direct electrolytic metallization, when the metal layer formed in c) has a thickness allowing electrolytic metallization.
Patent AU-5940790-A (AU)
Title: A device for dispensing flowing substances
Inventor: LUNDBACK RUNE
IPC: A47G19/12
Filed: 1990-06-19
Abstract: A dispensing device for flowing substances is attachable to a container and comprises an outlet tube of flexible material adapted to be dependent from the container and at the bottom terminated by an outlet opening. The dispensing device comprises valve arrangement for controlling flow of the substance through the device. Furthermore, the dispensing device comprises an intermediate piece comprising a first portion for releasably securing the outlet tube to the intermediate piece and a second portion for releasably securing the intermediate piece to communicate with a discharge opening of the container. The intermediate piece comprises a valve seat for restricting movement upwardly of the valve arrangement on squeezing of the flexible outlet tube.
Patent AU-6030498-A (AU)
Title: An apc mutation associated with familial colorectal cancer in ashkenazi jews
Inventor: LAKEN STEVE
IPC: C12Q1/68
Filed: 1998-01-21
Abstract: During routine screening of a patient with a family history of colorectal cancer for truncating APC mutations, a novel missense mutation was identified. Upon further evaluation, it was found that 6% of Ashkenazi Jews carry this mutation, and that it was present in  DIFFERENCE 20% of Ashkenazis with a family history of CRC. Probes, methods, and kits for identifying individuals affected with this missense mutation are provided.
Patent AU-6052690-A (AU)
Title: Kinetic enzyme assay for determining the co2 content of body fluids using pep carboxylase with inhibitor
Inventor: CUNNINGHAM BRYCE A
IPC: C12Q1/48
Filed: 1990-07-20
Abstract: An improved kinetic assay is provided for spectrophotometrically determining dissolved carbon dioxide (CO2) in body fluid wherein at pH 8.0 the CO2 is present substantially as bicarbonate ion (HCO3). The sample is subjected to a reaction mixture containing phosphoenolpyruvate (PEP) and phosphoenolpyruvate carboxylase (PEPC) which enzymatically catalyzes conversion of HCO3 to oxaloacetate (OA). The OA produced is subject to a second reaction mixture containing NADH and malate dehydrogenase (MDH) which reduces the OA to malate and oxidizes the NADH to NAD+. The CO2 level in the sample may be indirectly determined by measuring the change in NADH concentration. An inhibitor is added to the reaction mixture which renders the reaction kinetics of the system essentially first order over the entire bicarbonate concentration range of interest. Best results have been obtained through use of an inhibitor which provides an anion selected from the group consisting of Cl03, Cl04, SCN, or I.
Patent AU-6077599-A (AU)
Title: Method for improving the gene transfer of genetic material in mammalian cells through the use of p21 (waf-1)
Inventor: DORKEN BERND
IPC: C12N15/86
Filed: 1999-07-12
Abstract: The invention relates to a method for stabilizing and improving the gene transfer of genetic material in mammalian cells, characterized in that the gene or its cDNA is expressed in the target cell with simultaneous expression of the cell cycle regulator p21, which prevents apoptosis.
Patent AU-6288490-A (AU)
Title: Hose construction, coupling therefor and methods of making the same
Inventor: SANDERS JOHN D
IPC: F16L33/213
Filed: 1990-08-30
Abstract: A hose construction, coupling therefor and methods of making the same are provided, the hose construction comprising a tubular hose and a coupling secured to one end of the tubular hose, the inner peripheral surface of the tubular hose comprising an inner corrugated hose made of polymeric material and having inwardly convex projections with recesses therebetween and extending from one end of the tubular hose to the other end thereof, the coupling having an insert disposed in the one end of the tubular hose and being radially outwardly expanded into sealing relation with the inner corrugated hose, the insert having an outer peripheral surface defined by a plurality of outwardly convex projections with recesses therebetween, the projections of the insert being respectively received in the recesses of the inner hose and the projections of the inner hose being respectively received in the recesses of the insert whereby the interior of the tubular hose is substantially sealed to the interior of the coupling.
Patent AU-6357796-A (AU)
Title: Process and device for influencing liquid drops in a gas stream
Inventor: FOERSTER MALTE E C
IPC: B03C3/28
Filed: 1996-06-19
Abstract: PCT No. PCT/EP96/02651 Sec. 371 Date Apr. 18, 1997 Sec. 102(e) Date Apr. 18, 1997 PCT Filed Jun. 19, 1996 PCT Pub. No. WO97/00116 PCT Pub. Date Jan. 3, 1997A method of separating liquid drops from a gas stream includes the step of introducing the gas stream having a temperature greater than 600 DEG  C. into shaped elements having very narrow channels through which the gas stream flows, wherein the shaped elements are of a material that becomes conductive at high temperatures and further includes the step of selecting the width of the narrow channels based on the gas stream velocity such that turbulence is generated along the flow path causing the liquid drops to strike the channel walls and deposit thereon. The apparatus for separating liquid drops from a gas stream includes a plurality of shaped elements having very narrow channels through which the gas stream having a temperature greater than 600 DEG  C. flows, the shaped elements combined to a compound structure and are of a material that becomes conductive at high temperatures and the channels having a width based upon the gas stream velocity to effect turbulence along the flow path causing the liquid drops to strike the channel walls and deposit thereon.
Patent AU-6452080-A (AU)
Title: Liquid sample collector
Inventor: TURNER R C
IPC: A61B5/00
Filed: 1980-11-19
Abstract: A collector device for collecting, metering and holding a small sample of liquid, e.g. a drop of blood taken from a finger prick, comprises a vessel (10, 11 or 10A, 52A) provided with an opening (20 or 20A) closed by a plug (22 or 22A), and a screwthreaded cap (15 or 15A) having a protruding spigot (30 or 30A) which, when the cap is screwed fully onto the vessel, enters the opening and pushes the plug down into the interior of the vessel. The plug is formed at its outer end with an outwardly facing recess (24), e.g. part- spherical, and the spigot is formed at its end which enters the opening with a tapering conical formation (31) adapted to enter the recess (24). In use, with the cap (15 or 15A) removed the recess (24) is filled with a quantity of liquid, the cap is then partly replaced to cause the spigot (30 or 30A) to abut the end of the plug (22 or 22A) so that its conical formation (31) enters the recess (24) and displaces excess liquid therefrom, trapping a metered sample of liquid of predetermined volume, less than the volume of the recess, in the space defined between the abutted ends of the plug and spigot. The cap (15 or 15A) is then screwed fully home causing the spigot to push the plug down until it falls into the vessel, thus transferring the metered liquid sample into the vessel whose opening (20 or 20A) is now closed by the spigot (30 or 30A). The device enables a metered quantity of blood to be collected and transferred into the closed vessel for subsequent analysis, without contamination of the exterior of the device by the blood, and without the use of delicate metering devices such as capillary tubes to meter the blood sample. A latch connection (55A, 59A) may be provided between the cap (15A) and a removable lid (52A) of the collection vessel whereby when the cap is unscrewed it slowly withdraws the lid and opens the vessel.
Patent AU-6684800-A (AU)
Title: Device and method for blow forming containers
Inventor: CHOINSKI JULIAN
IPC: B29C49/42
Filed: 2000-07-25
Abstract: The invention relates to a method and a device for blow forming containers made of thermoplastic material. The parisons used are initially tempered and then formed into containers in the area of at least one blowing station. Molds (8, 9) for initially providing the contours of the container are supported on mold carriers (4, 5). At east two parisons are simultaneously formed into containers inside each blowing station. Positioning of the parisons is effected is such a manner that the parisons adopt a position (47) when fed into the blowing station that differs from their position during the blowing process. Relative spacing between parisons is changed from the moment in which they are fed into the blowing station until the moment in which they adopt the position for blowing.
Patent AU-6711996-A (AU)
Title: Method for powder coating and powder for use in said method
Inventor: ARVERUS HIKAN
IPC: B05D3/02
Filed: 1996-08-09
Abstract: A method and a powder for powder coating in which objects (2) which are to be powder coated are prepared in order to temporarily retain the powder, whereafter the powder is applied onto the object in a layer which is retained on the object until the powder, by means of melting and transformation to a solid state by means of curing, is caused to form a coating layer on the surfaces of the object. The powder is prepared in order to have a low melting and softening temperature below about 100  DEG C and preferably 60-100  DEG C, and comprises an initiator system arranged to bring the powder material to curing under the influence of electromagnetic radiation. The powder prepared in this way is heated on the object to a temperature such that it melts and forms an adherent layer on the coated surfaces of the object. Thereafter, this layer is subjected to the radiation, thus curing it to a coating layer covering the powder-coated surfaces.
Patent AU-6894496-A (AU)
Title: Prefabricated facade element for buildings
Inventor: JOHANSSON BENGT
IPC: E04B1/14
Filed: 1996-09-02
Abstract: The present element invention relates to a prefabricated facade element (1) for buildings comprising a thermal insulation (3) accommodated internally within the element enclosed by an inner leaf (5) facing inwards towards the interior of an intended building and an outer leaf (6) facing outwards from the interior of said building. The inner leaf (5), which consists of light clinker concrete, is securely attached to a border (8) of light clinker material extending around the insulation (3) and is provided with internal reinforcement (9) extending into the border (8). The surface leaf (6) with the reinforcement (10) applied to it is so arranged as to be secured by the aforementioned inner leaf (5) with its associated border (8) in such a way that it is capable of absorbing the forces which give rise to periodic movements.
Patent AU-7314098-A (AU)
Title: New chromene compounds, a process for their preparation and pharmaceutical compositions containing them
Inventor: LAVIELLE GILBERT
IPC: C07D491/052
Filed: 1998-06-24
Abstract: Hexahydro-chromeno-Ä3,4-cÜ-pyrrole derivatives of formula (I), their enantiomers, diastereoisomers and salts are new. m = 0-3; n = 0-3; n+m = 2 or 3; p = 1-6; the junction between rings B and C is trans; X = CN or -CONR4R5; R4, R5 = H, 1-6C alkyl, 3-7C cycloalkyl or optionally substituted aryl; A = sigma bond or -NR-CO-, -CO-NR-, -NR-SO2-, or -SO2-NR-; R = H or 1-6C alkyl; R1, R2 = H or 1-6C alkyl; R3 = H or phenyl, naphthyl or heteroaryl (all optionally substituted by one or more halo, 1-6C alkyl or alkoxy, OH, CN, NH2, NO2, COOH, 1-6C perhaloalkyl, sulphonyl, acylamino, 1-6C alkylsulphonyl, or 1-6C alkyl sulphonylamino), aryl or heteroaryl (both substituted by A'-Cy), 2-indolinon-5-yl, or, when A is a sigma bond, aryloxy or arylthio; A' = sigma bond or 1-6C alkylene or alkenylene, (in which one C atom may be replaced by O or S), -NR-CO-, -CO-NR-, -NR-SO2-, or -SO2-NR-; Cy = aryl or heteroaryl (optionally substituted); provided that when n = 0, then m is other than 2, when n = 1, R1, R2 = H, A = sigma bond and p = 1, then R3 is not phenyl nor pyridyl, when n = 1, R1 & R2 = H, A = sigma bond, R3 is not H, when n = 1, R1 & R2 = H, A = -NH-CO-, then R3 is other than H, phenyl, naphthyl, thienyl, furyl, pyrrolyl, pyridyl, (all optionally substituted by one or more halo, trihalomethyl, alkoxy or OH).
Patent AU-7381096-A (AU)
Title: Water-spreading coating having surfaces of silica particles coated with a metal oxide
Inventor: HUANG TZU-LI J
IPC: C09K3/18
Filed: 1996-09-30
Abstract: A silica-based water-spreading coating having surfaces of silica particles coated with a metal oxide. The metal comprises aluminum, gallium, germanium, tin, indium, arsenic, antimony or vanadium. The water-spreading coating may be applied to a retroreflective sheeting on a traffic sign.
Patent AU-7389291-A (AU)
Title: Method for production of fluid stable aggregate
Inventor: HATSUDA TAKUMI
IPC: C08J3/24
Filed: 1991-03-27
Abstract: A method for the production of a fluid stable aggregate, which comprises mixing (A) 100 parts by weight of an absorbent resin powder possessing a carboxyl group, (B) 0.01 to 30 parts by weight of a cross-linking agent, and (C) 0 to 50 parts by weight of water, and (D) 0 to 60 parts by weight of a hydrophilic organic solvent in a high-speed stirring type mixer which is provided with an inner surface formed substantially of a substrate (I) possessing a contact angle of not less than about 60 DEG  with respect to water and a heat distortion point of not lower than about 70 DEG C under the stirring condition of not less than 600 m/min of a peripheral speed of a leading-end of a stirring blade and thereafter completing reaction of said absorbent resin powder (A) with said cross-linking agent (B) under the condition that total kinetic energy F added to a mixture during the reaction is satisfied by the following equation: <MATH> wherein the kinetic energy Fa per minute added during the reaction is not more than 600 joule/kg.
Patent AU-7447491-A (AU)
Title: Endovascular electrolytically detachable guidewire tip
Inventor: GUGLIELMI GUIDO
IPC: A61B19/00
Filed: 1991-01-03
Abstract: A guidewire (10,42) for use in endovascular electrothrombosis in combination with a microcatheter (44), the guidewire comprising:a core wire having a main body (12,16;32) and a distal portion (18,26;36,46); anda coil (28,56) coupled to said main body (12,16,32) via said distal portion (18,26,36,46) and comprised of material not susceptible to electrolytic disintegration in blood, said coil (28,56) containing no internal reinforcement and being for endovascular insertion within a vascular cavity;   wherein said distal portion (18,26,36,46) is susceptible to electrolytic disintegration in blood whereby, on the application of current to the guidewire (10,42) when said coil (28,56) is disposed in the vascular cavity, endovascular electrothrombosis can be performed and at least one portion of said distal portion (18,26,36,46) electrolytically disintegrated to detach said coil (28,56) from said main body (12,16,32).
Patent AU-7586987-A (AU)
Title: System for over-the-air reprogramming of communication receivers
Inventor: DAVIS WALTER LEE
IPC: G08B3/10
Filed: 1987-01-02
Abstract: PCT No. PCT/US87/00004 Sec. 371 Date Jun. 11, 1987 Sec. 102(e) Date Jun. 11, 1987 PCT Filed Jan. 2, 1987.A communication receiver is disclosed which can decode signals transmitted by radio frequency propagation. A programmable controller uses instructions in a non-volatile reprogrammable memory to decode and process the signals, and to output the information contained in the signals in a useable form. The controller also responds to predetermined signals by decoding and processing information for new decoding and operating instructions, and stores the data in a temporary memory. Logic circuitry responds to subsequent predetermined signals to enable selective reprogramming of the non-volatile reprogrammable memory by data stored in the temporary memory to alter the decoding characteristics of the receiver.