baber/WOPTO huggingface dataset:
Patent EP-0971945-B1 (EP)
Inventor: LEES ANDREW
IPC: A61P37/04
Filed: 1998-03-24
Granted: 2004-10-06
Abstract: A method for producing a conjugate vaccine includes mixing a uronium salt reagent with a first moiety (e.g., a polysaccharide). According to the invention, the uronium salt reagent has a chemical structure corresponding to formula I:wherein R1 is defined aswherein R6 represents the carbon, hydrogen, and optionally one or more heteroatoms which, together with the nitrogen atom to which they are attached, constitute a 5 to 10 membered heterocyclic ring, which may be substituted or unsubstituted. R2, R3, R4, and R5, each independently represents a hydrogen atom, a substituted or unsubstituted alkyl having 1 to 6 carbon atoms, a substituted or unsubstituted alkenyl having 2 to 6 carbon atoms, or an alkynyl having 2 to 6 carbon atoms. Alternatively, R2 and R3, when taken together, can represent the carbon, hydrogen, sulfur, nitrogen, or oxygen atoms necessary to complete a 5 to 7 membered heterocyclic ring with the nitrogen atom to which they are attached. Likewise, R4 and R5, when taken together, can represent a similar heterocyclic ring. X- represents an acid anion (e.g., Cl-, Br-, F-, I-, PF6-, and BF4-). Also in this method, a second moiety (e.g., a protein, a peptide, or a lipoprotein) is mixed with the first moiety. The first moiety and the second moiety react together to form a conjugate.
Patent EP-0963502-B1 (EP)
Inventor: BEST BRUNO
IPC: E21B17/05
Filed: 1998-02-24
Granted: 2003-05-02
Abstract: L'invention concerne un outil à trains de sonde (1) prévu pour être utilisé dans un forage dans une formation de terre. Cet outil comprend un premier élément (1A) pouvant être raccordé à une partie supérieure d'un train de sonde (3) et un deuxième élément (5) pouvant être relié à une partie inférieure d'un train de sonde (7). Cet outil comporte également des moyens formant paliers (11) permettant la rotation du premier élément par rapport au deuxième élément, autour de l'axe longitudinal (90) du train de sonde, et des moyens de transfert de rotation (15) pour transférer la rotation du premier élément, autour de l'axe longitudinal; au deuxième élément. En outre, des moyens de commande (28) sont prévus pour libérer de manière sélective les moyens de transfert de rotation de manière à assurer la rotation du premier élément par rapport au deuxième élément à l'aide du moyen formant palier.
Patent EP-0980449-B1 (EP)
Inventor: CLARK JOHN C
IPC: D06M13/425
Filed: 1998-04-20
Granted: 2011-05-25
Abstract: A process is described which imparts exceptional antisoiling, anti-staining and repellent properties to carpets. The process makes use of a water-based exhaustion process wherein the water-based treating solution contains (1) glassy fluorochemical material, glassy hydrocarbon material, or combinations thereof; (2) a stainblocking material; (3) a polyvalent metal salt, acid, or combinations thereof; and (4) water. Subsequent to exhaustion, the wet treated carpet is heated, usually in a steaming step, rinsed, and dried in a dry heat oven.
Patent EP-0991172-B1 (EP)
Inventor: SAKAKIBARA KENICHI
IPC: H02M7/06
Filed: 1998-05-20
Granted: 2003-09-24
Abstract: This single phase rectification apparatus connects a full wave rectification circuitry (3) to a single phase A.C. power source (1) through a reactor (2), connects a pair of smoothing diodes (5) which is connected in series to one another between the output terminals of the full wave rectification circuitry (3), connects a series connection circuitry of a pair of diodes (4) in parallel to the series connection circuitry (5) of the pair of the smoothing diodes, connects the center point of the pair of the diodes (4) and the center point of the pair of the smoothing diodes (5) to one another, and connects an A.C. capacitor (6) between one input terminal of the full wave rectification circuitry (3) and the center point of the pair of the smoothing diodes (5), so that decrease in size and in cost are realized for the single phase rectification apparatus in its entirety. <IMAGE>
Patent EP-0993460-B1 (EP)
Inventor: TAVERAS ARTHUR G
IPC: C07D401/12
Filed: 1998-06-15
Granted: 2004-09-15
Abstract: Novel compounds of formula: (1.0) or a pharmaceutically acceptable salt or solvate thereof, wherein: a represents N or NO<->; R<1> and R<3> are the same or different and each represents halo; R<2> and R<4> are each independently selected from H and halo, provided that at least one of R<2> and R<4> is H; each dotted line (---) represents an optional bond; X is N, C when the optional bond to X is present, or CH when the optional bond to X is absent; T is a substituent selected from (A) or (B): Z represents O or S; R represents -C(O)N(R<10>)2, -CH2C(O)N(R<10>)<2>, -SO2R<10>, -SO2N(R<10>)2, -C(O)R<11>, -C(O)-O-R<11>, alkyl, aryl, aralkyl, cycloalkyl, heterocycloalkyl or heteroaryl; R<5> represents alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl, OR<12>, NR<12>H, SH, SR<12>, SOR<12> (where R<12> is not H) or SO2R<12> (where R<12> is not H); and each R<10> independently represents H, alkyl, aryl, or aralkyl; R<11> is alkyl, aryl, aralkyl, heteroaryl, or heterocycloalkyl; R<12> is selected from H, alkyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, or heterocycloalkyl. Also disclosed are methods of inhibiting farnesyl protein transferase and methods for treating tumor cells.
Patent EP-0997042-B1 (EP)
Inventor: KUTTER MARTIN
IPC: H04N19/51
Filed: 1998-07-15
Granted: 2003-04-09
Abstract: A method for marking a compressed digital video signal by embedding a digital signature in the compressed video signal, the signal representing a series of at least two video images, each image being divided into a plurality of regions, the signal including movement vectors representing the movement of the regions between the first and the second image, characterised in that it consists in modifying at least one of the coefficients X or Y of at least one of the movement vectors.
Patent EP-0988185-B1 (EP)
Inventor: PAUSCH TOBIAS
IPC: B60R21/231
Filed: 1998-06-09
Granted: 2001-09-19
Abstract: Die Erfindung betrifft ein Seitenairbagmodul mit einem Gassack für den Kopf-Thorax-Bereich des Fahrzeuginsassen, und ist erfindungsgemäß dadurch gekennzeichnet, daß ein dem Insassen (5) abgewandter Abschnitt (2) des Gassackes (4) in Fahrzeug-z-Richtung eine größere Länge als ein dem Insassen zugewandter Abschnitt (1) aufweist, daß der längere Abschnitt (2) quer zur Fahrzeug-z-Richtung zur Erreichung der Deckungsgleichheit mit dem kürzeren Abschnitt (1) in mindestens eine Falte (3a) gelegt ist, und daß beide Abschnitte (1, 2) zur Bildung des Gassacks (4) am Rand miteinander verbunden sind. Vorzugsweise bestehen der dem Insassen zugewandte und abgewandte Abschnitt aus mindestens je einem plattenförmigen Teil (1, 2). Der Gassack kann auch aus Teilen zusammengesetzt werden, die sich beim Aufblasen des Gassacks unterschiedlich dehnen, wobei mindestens ein dem Insassen zugekehrtes Teil des Gassacks eine geringere Dehnbarkeit als mindestens ein dem Insassen abgekehrtes Teil des Gassacks aufweist.
Patent EP-1006890-B1 (EP)
Inventor: MCCRORY JENNIFER J
IPC: A61F2/82
Filed: 1998-07-29
Granted: 2006-09-20
Abstract: An internal neck occlusion system treats an aneurysm (22) in a parent vessel (20). The parent vessel (20) defines a lumen (30). The aneurysm (22) includes a neck (26) and an inner wall defining a cavity (28) communicating with the lumen (30). The occlusion device (32) is configured for deployment within the cavity (28). The device (32) includes a collapsible member which is permeable to blood flow. The device (32) is arranged such that, when deployed within the cavity (28), the member bridges the neck (26) of the aneurysm (22) and is in contact with the inner wall. In treating the aneurysm (22), the device (32) is collapsed and endovascularly placed proximate the aneurysm (22). The device (32) is then expanded within the cavity so as to bridge the neck (26) of the aneurysm (22). An embolic agent (50) can be injected into the cavity (28) after the neck occlusion device is deployed.
Patent EP-0998501-B1 (EP)
Inventor: KOLBE HANNO V J
IPC: C12N15/87
Filed: 1998-07-20
Granted: 2002-03-27
Abstract: The invention concerns novel cationic polymers of formula (I) in which n is a whole number between 0 and 5 and p is a whole number between 2 and 20,000, more particularly p ranges between 10 and 18,000, and advantageously between 200 and 1,000, characterized in that: at least 10%, advantageously 30 to 80%, preferably 70%, of the free NH2 functions are substituted by identical or different hydrophilic R groups; said cationic polymer can further comprise at least a targeting element associated covalently or not with the free NH2 functions and/or said hydrophilic R groups provided that said cationic: polymer contains at least 20%, preferably at least 30%, of free NH2 functions. The invention also concerns a complex comprising at least said cationic polymer associated with at least a therapeutically active substance, in particular a nucleic acid comprising at least a negative charge. The invention is useful for transferring a nucleic acid into target cells, in particular for gene therapy.
Patent EP-1018936-B1 (EP)
Inventor: ARENSON RONALD L
IPC: A61M25/00
Filed: 1998-10-15
Granted: 2007-12-19
Abstract: A magnetically directable guidance system useful in, for example, medical magnetic resonance imaging is provided, as well as methods of directing the traverse of a device directable by the remote guidance system to a remote destination. A directable device and methods of use thereof are also disclosed. In one embodiment, the device is a catheter directable using a magnetic resonance imaging system. In another embodiment, the method includes interventional radiological diagnostic and therapeutic procedures.
Patent EP-1051233-B1 (EP)
Inventor: BANKS ROBERT
IPC: B01D53/047
Filed: 1998-10-30
Granted: 2004-03-10
Abstract: L'invention concerne un procédé permettant d'extraire des composants gazeux individuels d'un mélange de gaz à l'intérieur d'un récipient à atmosphère contrôlée. Dans ce procédé on utilise un dispositif comprenant une première et une seconde chambre disposées en parallèle de manière que le mélange gazeux le traverse depuis leurs extrémités d'entrée jusqu'à leurs extrémités de sortie. Ces chambres contiennent un matériau adsorbant présentant diverses affinités avec les composants gazeux du mélange. Le procédé consiste à introduire le mélange gazeux dans la première chambre de manière à le mettre sous pression et à faire circuler simultanément un flux de purge entre l'extrémité de sortie de la première chambre et la seconde chambre afin de séparer le gaz adsorbé du matériau adsorbant dans la second chambre. Une impulsion de gaz de purge est ensuite envoyée dans la seconde chambre à partir de l'extrémité de sortie de la première chambre, afin de séparer le gaz adsorbé du matériau adsorbant dans la seconde chambre, la vitesse d'écoulement du flux de purge étant inférieure à celle de l'impulsion de purge.
Patent EP-1028840-B1 (EP)
Inventor: TINKER PAUL
IPC: B29C51/02
Filed: 1998-11-05
Granted: 2002-10-02
Abstract: A method of making an article of sanitaryware from a composite of a facing sheet (10) of an acrylic material and a backing sheet (14) of a thermoplastic material other than an acrylic material, includes the steps of heating each of the facing sheet (10) and the backing sheet (14) to a temperature within the vacuum forming range; bringing the facing sheet (10) and the backing sheet (14) together between a nip (18) between a first roller (20) and a second roller (22) to exclude any gasses trapped or formed between the two sheets (10, 14) and to bond the two sheets (10, 14) together to form the composite; and placing the composite in a vacuum forming mould and applying suitable conditions of pressure to mould the article from the composite.
Patent EP-1135255-B1 (EP)
Inventor: PAQUE MICHAEL W
IPC: B65C3/00
Filed: 1998-11-06
Granted: 2010-06-16
Abstract: The present invention relates to a laminating and adhesive transfer apparatus for use with a pair of removable feed rolls. The removable feed rolls carrying a supply of stock material to be unwound. The apparatus comprises a frame constructed and arranged to removably mount the feed rolls. A pair of nip rollers are rotatably mounted to the frame. The nip rollers define a nip area therebetween with a feed side and a discharge side. An actuating mechanism is constructed and arranged to affect nip roller rotation. The frame is constructed and arranged such that, when the feed rolls are removably mounted thereto, a master can be inserted between the feed rolls, the stock materials can then be unwound from each of feed rolls so as to be disposed on opposing sides of the master, and the master and the stock materials can thereafter be fed together into the feed side of the nip rollers. The nip rollers are constructed and arranged to apply pressure to the master and stock materials being fed into the feed side of the nip rollers as a result of the nip roller rotation so as to perform a laminating or adhesive transfer process to the master and stock materials and subsequently discharge the processed master and stock materials outwardly from the discharge side. An exit tray provides a substrate supporting surface positioned and configured to receive and support the processed master and stock materials being discharged from the nip rollers in a substantially flat relation to thereby prevent downward bending of the processed master and stock materials.
Patent EP-0982384-B1 (EP)
Inventor: VAN DIJK GIJSBERT
IPC: C09J111/00
Filed: 1999-07-01
Granted: 2004-10-06
Abstract: A brushable adhesion adjuvant for bonding of rubbers or gums to substrate surfaces can be obtained by reaction of rubber chlorinated with an organic bromine compound mainly at the allyl site, in the presence of silicic acid and carbon black particles in solution or suspension.  A brushable adhesion adjuvant for bonding of rubber or gums to substrate surfaces is obtained by reaction of (wt.%): (a) chlorinated rubber (50-90), (b) non-halogenated rubber (10-50), where the amount of rubber in (a) and (b) together = 100 wt.%, with (c) an organic bromine compound (3-20), able to brominate the rubber mainly at the allyl site, in the presence of (d) silicic acid (0-50), and (e) carbon black particles in solution or suspension. Independent claims are included for: (1) a brushable adhesion adjuvant (BAA) obtained by reaction of components (a) - (e) above; (2) a process for bonding substrate surfaces with addition of metal powder; (3) a process for adhesive bonding of rubber and gum particles to substrate surfaces in which the unprimed substrate surface is coated with the BAA, is coated with one or more adhesive layers, is optionally coated with rubber particles, and the assembly formed is vulcanized.
Patent EP-1001128-B1 (EP)
Inventor: SCHWAB ARMIN
IPC: G01M3/04
Filed: 1999-11-05
Granted: 2004-08-11
Abstract: The method involves providing a sensor (18) in the insulating gap between glass panes, and exposing it to the atmosphere in the gap. The sensor reacts to a change in the gas composition and outputs a signal. The sensor may react by changing color. The sensor may react to a component of air such as oxygen or nitrogen, if it should exceed a threshold. An insulating glass pane is also claimed.
Patent EP-1022415-B1 (EP)
Inventor: REFFLINGHAUS BERND
IPC: H01F7/08
Filed: 1999-12-08
Granted: 2005-03-02
Abstract: The cylinder lock core (5) is normally turned by a profiled key which releases locking plungers but an additional lock is provided by the armature (15), of an electromagnet (11), which is held by a spring (23) until the magnet is energized. The magnet is housed within a magnetic material (21).
Patent EP-0987248-B1 (EP)
Inventor: KELLEY JAMES LEROY
IPC: A61K31/16
Filed: 1994-05-10
Granted: 2002-09-04
Abstract: Novel compounds of formula (I) <CHEM> together with their salts and solvates have a number of uses in medicine, in particular as central muscle relaxants.
Patent EP-0985666-B1 (EP)
Inventor: NAKAO KAZUNARI
IPC: C07D405/06
Filed: 1999-09-03
Granted: 2003-11-05
Abstract: This invention provides a compound of the following formula: <CHEM> or the pharmaceutically acceptable salts thereof wherein R<1> is H or C1-4 alkyl; R<2> is C(=L')R<3> or SO2R<4>; Y is a direct bond or C1-4 alkylene; L and L' are independently oxygen or sulfur; Q is selected from the following: C1-6 alkyl. halo-substituted C1-4 alkyl, optionally substituted C3-7 cycloalkyl, optionally substituted phenyl or naphthyl, optionally substituted 5 or 6-membered monocyclic aromatic group;  R<3> is -OR<6>, -NR<7>R<8>, N(OR<1>)R<7> or a group of formula: <CHEM> Z is a direct bond, O, S or NR<5>; R<4> is C1-6 alkyl, halo-substituted C1-4 alkyl, optionally substituted phenyl or naphthyl; R<5> is C1-4 alkyl or halo-substituted C1-4 alkyl; R<6> is C1-4 alkyl, C3-7 cycloalkyl, C1-4 alkyl-C3-7 cycloalkyl, halo-substitutued C1-4 alkyl, optionally substituted C1-4 alkyl-phenyl or phenyl; R<7> and R<8> are each selected from the following: H, optionally substituted C1-6 alkyl, optionally substituted C3-7 cycloalkyl, optionally substituted C1-4 alkyl-C3-7 cycloalkyl, and optionally substituted C1-4 alkyl-phenyl or phenyl; X is each selected from halo, C1-4 alkyl. halo-substitutued C1-4 alkyl, OH, C1-4 alkoxy, halo-substitutued C1-4 alkoxy, C1-4 alkylthio, NO2, NH2, di-(C1-4 alkyl)amino and CN; n is 0, 1, 2 or 3; and r is 1, 2 or 3. This invention also provides a pharmaceutical composition useful for the treatment of a medical condition in which prostaglandins are implicated as pathogens.
Patent EP-1131233-B1 (EP)
Inventor: FAGGIOTTO ELBERINO
IPC: B60S1/38
Filed: 1999-04-06
Granted: 2004-09-29
Abstract: Accessory to clean and recondition the rubber profile (12) of windscreen wiper arms (13) comprising a containing body (14) shaped substantially like an upside-down U, open on one side (14a) and housing scraping and/or abrasive means The scraping and/or abrasive means may consist of scraping blades or cylindrical milling wheels made to rotate by rubber rollers.
Patent EP-1060331-B1 (EP)
Inventor: BENDERS JAN
IPC: F02M21/02
Filed: 1999-03-03
Granted: 2004-06-30
Abstract: The system includes a metering valve for each cylinder including a main valve and an auxiliary valve. The auxiliary valve is electrically controlled ad via a mechanical, pressure controlled amplifier mechanism, the main orifice in the metering valve is opened.
Patent EP-1066247-B1 (EP)
Inventor: TUNG ROGER D
IPC: A61P31/18
Filed: 1999-03-31
Granted: 2006-11-22
Abstract: The present invention relates to compounds, methods and pharmaceutical compositions for inhibiting proteases, particularly serine proteases, and more particularly HCV NS3 proteases. The compounds, and the compositions and methods that utilize them, can be used, either alone or in combination to inhibit viruses, particularly HCV virus.
Patent EP-1112232-B1 (EP)
Inventor: NEWTON ROBERT KINGSLEY
IPC: C02F3/30
Filed: 1999-06-29
Granted: 2006-02-01
Abstract: A method of treating waste water and particularly sewerage is disclosed. The method involves treating the conduit system making up the sewerage network before it reaches a typical sewerage treatment plant. A key feature of the method involves introducing an inoculum of selected micro-organisms into a quiescent zone in the conduit system. The quiescent zone is where the water is significantly slowed in its passage along the conduit system and may even be temporarily stationary eg, a pumping well or low point in two sections of pipe. Applicant has ascertained that undesirable micro-organisms tend to flourish in these quiescent zones. By introducing the inoculum a competitive culture of favourable micro-organisms is incubated which is able to out compete the undesirable micro-organisms and lead to break down and degradation of the sewerage in the conduit system before it gets to the treatment plant. Further by suppressing the undesirable micro-organisms damage to the conduit system and problems with odorous gases are reduced.
Patent EP-1105323-B1 (EP)
Inventor: ARSENAULT CATHLEEN M
IPC: B65D83/14
Filed: 1999-07-27
Granted: 2004-03-17
Abstract: Actuator system is used to dispense a defined volume of a formulation from a pressurized vial. The system houses the vial in a receptacle of a base section that also includes a dispensing section (e.g., a funnel) through which the formulation is sprayed. The system includes a sleeve that fits over at least the vial and that can be pumped by the user to controllably spray the formulation from the vial onto the host animal. For instance, in a preferred mode of operation, the user places the system onto the host at the desired treatment site and then pushes or pulls down on the sleeve. This actuates a valve mechanism on the vial to spray an amount of the formulation through the dispensing section onto the host.
Patent EP-1115579-B1 (EP)
Inventor: TAYLOR JAMES PHILIP
IPC: B41M5/323
Filed: 1999-08-10
Granted: 2002-11-20
Abstract: A monophase solid solution comprising a plurality of color formers selected from the group consisting essentially of the fluoran type, phthalide type, phenoxazine type, phenothiazine type, rhodamine lactam type, leuco-auramine type, triphenylmethane type, spiropyran type, benzoxazine type, quinazoline type of color formers and mixtures thereof, preferably wherein the color forming materials are selected from the fluoran and phthalide type of color former and mixtures thereof.
Patent EP-1045768-B1 (EP)
Inventor: TSAGAS NICOLAOS
IPC: B60C23/04
Filed: 1999-10-12
Granted: 2004-07-07
Abstract: The present invention relates to a device which indicates the safety limits of the air pressure in each one of the pneumatic tires of a vehicle by transmitting appropriate information from the wheels to the driving control board. Transmission of information is based on the capacitive coupling between rotating and non-rotating conductive annular surfaces (2-5, 12-19, 72-75) which are mounted into channels of insulated bases (6-9) fixed in the available space between the bearing flange, the braking system and the wheel bearings (66) and are forming cylindrical and plane capacitors. An electronic circuit incorporates these capacitors as basic elements for its operation, and also an AC bridge (20) to give an automatic compensation by measuring the differential capacitance for each pair of the wheels to avoid faulty indication due to causes like humidity, temperature, etc. Also a simple electronic circuit can be used for each one of the wheels. A tire pressure sensor (1) comprises a semiconductor membrane (30) with an electrode (33) which is shorting out the rotating conductive surfaces (2, 3, 12, 13, 16, 17, 72, 73) when the tire pressure deviates from the safety limits resulting in a change of the original frequency and giving visual display or audio indication.