baber/WOPTO huggingface dataset:
Patent CA-2526036-A1 (CA)
Title: Methods and compositions for diagnosing and treating disorders involving angiogenesis
Inventor: CAI JENNY HONG
IPC: C12Q1/68
Filed: 2004-05-10
Abstract: The present invention relates to polynucleotides associated with angiogenesis-related disorders. The present invention also relates to feline endostatin genes, novel genes associated with angiogenesis-related disorders, such as cancer. The invention encompasses endostatin nucleic acids, recombinant DNA  molecules, cloned genes or degenerate variants thereof, endostatin gene products and antibodies directed against such gene products, cloning vectors containing mammalian endostatin gene molecules, and hosts that have been genetically engineered to express such molecules. The invention further relates to methods for the identification of compounds that modulates the expression of endostatin genes and gene products and to using such compounds as therapeutic agents in the treatment of angiogenesis-related disorders, e.g., cancer. The invention also relates to methods for the diagnostic evaluation, genetic testing and prognosis of angiogenesis-related disorders, e.g., cancer, and to methods and compositions for the treatment these disorders.
Patent CA-2527019-A1 (CA)
Title: Neuroactive 13,24-cyclo-18,21-dinorcholanes and structurally-related pentacyclic steroids
Inventor: COVEY DOUGLAS F
IPC: C07J71/00
Filed: 2004-05-28
Abstract: Novel pentacyclic steroids and pentacyclic D-homosteroids comprising: (i) the tetracyclic steroid ring system or tetracyclic D-homosteroid ring system, respectively; (ii) a C(3) substituent selected from the group consisting of (a) a hydroxyl or carboxyl in the "-configuration and (b) a sulfate or other negatively charged moiety; and (iii) a fused fifth ring, the fused fifth ring comprising a hydrogen bond acceptor, and (a) in the case of the pentacyclic steroid the C(13) and C(17) carbons, or (b) in the case of the pentacyclic D-homosteroid the C(13) and C(17a) carbons, having utility as anesthetics and in the treatment of disorders relating to GABA function and activity.
Patent CA-2527301-A1 (CA)
Title: Oligonucleic acid-bearing composite and pharmaceutical composition containing the composite
Inventor: HIRABAYASHI KAZUKO
IPC: A61K47/24
Filed: 2004-05-28
Abstract: A composite comprising as a main ingredient a cationic ribosome composed of 2-O-(2-diethylaminoethyl)carbamoyl-1,3-O-dioleoylglycerol and phospholipid, the cationic ribosome bearing an oligonucleic acid. This composite can be administered in a living body and exerts medicinal effect therein, so that it can find practical use in pharmaceuticals. Thus, there is provided a preventive or therapeutic drug composition for diseases in which target molecules of the oligonucleic acid (target DNA, target RNA and target protein) take part, which drug composition comprises the above composite.
Patent CA-2527817-A1 (CA)
Title: Bundled printed sheets
Inventor: GRAVLEY LANE
IPC: B31B50/88
Filed: 2004-06-03
Abstract: A bundled of printed sheet (900), an apparatus (200) for the manufacture of bundled printed sheets, and methods (10) of making and using the bundled printed sheets with a plurality of printed sheets (910) in a stack each printed sheet having a cut-to-print registration variance.
Patent CA-2527931-A1 (CA)
Inventor: HARLING JOHN DAVID
IPC: C07D217/02
Filed: 2000-06-29
Abstract: Compounds of formula (I) wherein Q is a monocyclic or bicyclic aryl or heteroaryl ring; R1 is hydrogen; R2 is hydrogen or up to three substituents selected from halogen, NO2, CN, N3, CF3O-, CF3S-, CF3SO2-, CF3CO-, C1-8alkyl, C1-8alkenyl, C1-6alkynyl, C1-6perfluoroalkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-4alkyl-, C1-6alkylO-C1-6alkylCO-, C3-6cycloalkylO-, C3-6cycloalkylCO-, C3-6cycloalkyl-C1-4alkylO-, C3-6cycloalkyl-C1-4alkylCO-phenyl, phenoxy, benzyloxy, benzoyl, phenyl-C1-4alkyl-, C1-6alkylS-, C1-6alkylSO2-, (C1-4alkyl)2NSO2-, (C1-4alkyl)NHSO2-, (C1-4alkyl)2NCO-, (C1-4alkyl)NHCO-, or CONH2, or NR3R4 where R3 is hydrogen or C1-4alkyl, and R4 is hydrogen, C1-4alkyl, formyl, -CO2C1-4alkyl, or -COC1-4alkyl, or two R2 groups together form a carbocyclic ring that is saturated or unsaturated and unsubstituted or substituted by -OH or =O; X is halogen, C1-6 alkoxy, C1-6 alkyl, or C1-6 perfluoroalkyl, and; Y is hydrogen, halogen, C1-6 alkoxy, C1-6 alkyl, or C1-6 perfluoroalkyl; but excluding the compounds N-(5-iodo-1,2,3,4-tetrahydroisoquinolin-7-yl)-4-azidobenzamide and N-(5-iodo-1,2,3,4-tetrahydroisoquinolin-7-yl)-5-benzoyl-2-methoxybenzamide; and pharmaceutically acceptable salts or solvates thereof possess anticonvulsant activity and are useful in the treatment of a variety of disorders.
Patent CA-2529401-A1 (CA)
Inventor: AYTES SHELLEY
IPC: C07D223/16
Filed: 2004-06-16
Abstract: The present invention provides processes and intermediates for the preparation of 3-benzazepines and salts thereof which can be useful as serotonin (5-HT) receptor agonists for the treatment of , for example, central nervous system disorders such as obesity.
Patent CA-2529458-A1 (CA)
Title: Drive circuit and electric motor for submersible pumps
Inventor: YURATICH MICHAEL ANDREW
IPC: H02P6/08
Filed: 2004-06-21
Abstract: An electric submersible pump contains an AC permanent magnet motor having three or more phases A, B, C and has a drive circuit for supplying varying drive signals to all the phases of the motor at the same time. Each drive signal is constituted by a cyclically smoothly varying voltage applied to the corresponding motor phase during driving of the motor. The circuit comprises switches (902, 903) for each motor phase, a control arrangement for turning the switches (902, 903) on and off at a frequency greater than the frequency of the cyclically smoothly varying voltages, and a filter (907, 908) for filtering the output voltages of the switches (902, 903) to produce the cyclically smoothly varying voltages. Such a drive circuit drives all the phases of the motor continuously such that damaging transients will not arise and without requiring the motor emf or drive signals to be sinusoidal.
Patent CA-2529933-A1 (CA)
Title: Microwave oven cooking process
Inventor: KOOLS JOHAN
IPC: A23L5/10
Filed: 2004-06-25
Abstract: A microwave dry-fry cooking process includes the steps of providing a food product in or on a microwave cooking vessel and exposing the food product in or on the microwave cooking vessel to microwave energy in a microwave oven.  The food product includes a food load and a coating composition coated on the food load, where the coating composition comprises at least one microwave-absorbing oil or fat.
Patent CA-2530715-A1 (CA)
Title: Method and apparatus for implementing a sleep proxy for services on a network
Inventor: CHESHIRE STUART D
IPC: H04L12/40
Filed: 2004-04-29
Abstract: One embodiment of the present invention provides a system for implementing a sleep proxy. The system starts by receiving a request at the sleep proxy for information pertaining to a service provided by a device. In response to this request, the system determines if the device is a member of a list of devices for which the sleep proxy takes action. If so, the system determines if the sleep proxy can answer the request. If so, the sleep proxy sends a response to the request on behalf of the device. In a variation on this embodiment, if the system cannot answer the request on behalf of the device, the system sends a wakeup packet to the device, wherein the wakeup packet causes the device to exit a power-saving mode so that the device can respond to the request directly.
Patent CA-2530989-A1 (CA)
Inventor: TERWILLIGER RICHARD A
IPC: A61M36/12
Filed: 2004-05-12
Abstract: A delivery system and method for interstitial radiation therapy comprising a substantially axially stiff and longitudinally flexible elongated strand made of material, which is bio-absorbable in living tissue and a plurality of radioactive seeds dispersed in a predeterrnined array within the strand. The delivery system and method further customize the strand based on a prescription. The strands can have custom end spacings, which allow the optimal placing of seeds within the treatment tissue by implanting a plurality of strands to the same depth. A plurality of these strands can be implanted at the same time by the use of a guiding device.
Patent CA-2532213-A1 (CA)
Inventor: OGURA KAZUMASA
IPC: C10L3/10
Filed: 2005-04-08
Abstract: An impurity disposal system, which disposes of impurities in natural gas (or oil-associated gas) (11) into the ground, comprises an impurity removing device (13) for removing the impurities in a gas state, a compressor (15) for compressing the removed impurity gas (12) by a drive unit (14), and a drying device (18) for removing the moisture (17) in the compressed impurity gas (16), the dried compressed impurity gas (19) being disposed of into the aquifer (20).
Patent CA-2532347-A1 (CA)
Title: Combination of mglur2 antagonist and ache inhibitor for treatment of acute and/or chronic neurological disorders
Inventor: WICHMANN JUERGEN
IPC: A61K31/55
Filed: 2004-07-17
Abstract: The present invention relates to a method of treatment or prevention of acute and/or chronic neurological disorders, to a pharmaceutical composition comprising an inhibitor of acetylcholinesterase (AChE inhibitor) and a metabotropic Glutamate receptor 2 antagonist (mGluR2 antagonist), to the use of an AChE inhibitor and a mGluR2 antagonist in the preparation of a medicament, and. to kits comprising an AChE inhibitor and a mGluR2 antagonist.
Patent CA-2533675-A1 (CA)
Title: Side opening cargo rack
Inventor: WATSON BRAD E
IPC: B60R9/06
Filed: 2006-01-23
Abstract: A rack assembly secures articles to a motor vehicle having a liftgate. The liftgate defines a predetermined liftgate with, a bumper and a roof rack. The rack assembly includes first and second base mounts that are fixedly secured to the bumper. The rack assembly also includes first and second rack mounts that are fixedly secured to the roof rack. The rack assembly also includes a mounting rack that is pivotally secured to the first base mount and the first rack mount and removeably securable to the second base mount and second rack mount. The mounting rack provides securing devices for securing articles thereto.
Patent CA-2537946-A1 (CA)
Title: Arrangement for autonomous mobile network nodes to organize a wireless mobile network based on detected physical and logical changes
Inventor: THUBERT PASCAL
IPC: H04L12/28
Filed: 2004-10-04
Abstract: An autonomous wireless mobile network is established between mobile nodes configured as wireless autonomous robotic mobile access points. Each mobile node includes a mobility platform, an executable routing resource, and a standardized interface. The mobility platform is configured for supplying sensor data from attached physical sensors, and responding to motor commands from the standardized interface. The standardized interface is configured for converting each sensor datum into a corresponding sensor object, and converting received movement directives into the respective motor commands.  The executable routing resource is configured for maintaining a database of world objects representing attributes within an infosphere established by the wireless mobile network based on the sensor objects and received network objects. The executable routing resource also is configured for generating the received movement directives and executing network decisions based on periodic evaluation of the world database, and exchanging the world objects with other mobile nodes.
Patent CA-2538217-A1 (CA)
Inventor: LENTO JAMES A
IPC: A41D19/00
Filed: 2004-08-24
Abstract: The drum glove (10) of the present invention is designed to allow the wearer to hold and properly align a drumstick (22) in the hand. The glove has a sheath including a back covering and a palm covering for encasing the dorsal and ventral aspects of the hand, four tubular finger sleeves (14a, 14b, 14c, 14d) that are open-ended and permit the middle and distal phalanges to extend from the glove, a tubular thumb sleeve (12) that is open-ended and permits the distal phalanx of the thumb to extend from the glove, and between one and three elastic bands (16a, 16b, 16c) extending across the palm covering. The elastic bands (16a, 16b, 16c) are designed to replicate and enhance the natural sticking motions of the drummer. The elastic bands allow the drummer to hold the drumsticks (22) without unintentionally dropping them.
Patent CA-2541085-A1 (CA)
Title: Multiplayer gaming system and method of operation thereof
Inventor: MOSHAL MARTIN
IPC: A63F9/24
Filed: 2004-09-30
Abstract: A multiplayer gaming system (1) that is usable by a number of participating players to play a multiplayer game, comprises a plurality of player stations, each player station enabling a respective participating player to place a wager on an outcome of the multiplayer game and to play a separate instance of a same single-layer game having a plurality of possible results, and an application web server communicable with each one of the plurality of player stations.
Patent CA-2541650-A1 (CA)
Title: Modules for c0-extrusion dies
Inventor: CASTILLO RAFAEL
IPC: B29C48/255
Filed: 2006-03-09
Abstract: The present invention is a module used in a modular blown film co-extrusion die for extruding multi layer polymer materials in a tubular form. The module including an upper pancake section including an upper melt entry port and melt channels defined in one face thereof, wherein the melt channels communicating fluidly with the upper melt entry port and a lower pancake section including a lower melt entry port and melt channels defined in one face thereof, wherein the melt channels communicating fluidly with the lower melt entry port. The melt channels of the upper and lower pancake sections facing each other and separated by a divider plate, such that the upper pancake section together with one side of the divider plate defining a top melt path and the lower pancake section together with the other side of the divider plate defining a bottom melt path, wherein the top melt path producing a top melt layer and the bottom melt path producing a bottom melt layer.
Patent CA-2542480-A1 (CA)
Title: Apparatus and method for holding materials for the forming and joining thereof
Inventor: CAMPIAN JONATHON R
IPC: B32B38/18
Filed: 2004-10-15
Abstract: A machine cell (10)for the forming and joining of a first sheet material (A) to a second sheet material (B) includes an upper gate (100) and a lower nest (200). The lower nest (200) includes a vacuum pad (208) having a recessed channel (210) defined therein. A vacuum system (204) is fluidly connected to the recessed channel (210) to hold the first sheet material (A) to the lower nest (200) during the joining of the first and second sheet materials (A, B).  The machine cell (10) further includes an arrangement for aligning the first sheet material to the second sheet material.
Patent CA-2542748-A1 (CA)
Title: Decoupling clutch, particularly for marine
Inventor: TAMBA RICHARD TERRENCE
IPC: F16D25/0638
Filed: 2004-10-20
Abstract: Stand alone decoupling clutch (10) is used in drive shafts, eg of watercraft.  Clutch (10) is separate from any gearbox, etc, does not change the direction of rotation of the drive shaft, and has a single clutch area which allows slippage at any speed or torque. Electronic control system (44) controls slippage of the clutch (10) providing for low speed operation, high energy launches, driveline protection, etc. Slip speed is controlled sensing input shaft speed (38) and the output propeller speed (40) and altering hydraulic pressure accordingly on a clutch-compressing piston by opening direct-acting, high flow, electro-hydraulic solenoids (36).
Patent CA-2542963-A1 (CA)
Title: Inhibitors of cathepsin s
Inventor: MUTNICK DANIEL
IPC: C07D413/12
Filed: 2004-10-21
Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme.  The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
Patent CA-2543788-A1 (CA)
Title: An apparatus for automatically pointing a device at a target
Inventor: MCCULLEY RICH
IPC: B64C1/00
Filed: 2004-10-22
Abstract: A system for pointing a device at a given target has a sensor for sensing a number of positional information points of the target with the sensor relaying the positional information points to a controller. The controller is for computing a directional control information based on the relayed positional information points. The system also has an adjustment device for moving the device in a direction that bears a predetermined relationship to the target in response to the computed direction control information. The target moves and the sensor senses the positional information of the target and the sensor relays the positional information to the controller with the controller computing the directional control information to control the adjustment device. The adjustment device points the device at the target.
Patent CA-2544990-A1 (CA)
Title: Terpene ether developing solvent for photopolymerizable printing plates
Inventor: HENDRICKSON CONSTANCE MARIE
IPC: G03F7/32
Filed: 2004-11-04
Abstract: Flexographic printing plates are produced by exposing the photopolymer plates to a light source and washing out (developing) the masked out, non-exposed areas with a solvent. The invention provides terpene ether solvents suitable for use in the development of photopolymer printing plates. The solvents, which include terpene ethers alone or mixed with co-solvents and/or non-solvents, are effective in developing a large number of different photopolymer printing plates and can produce images superior to those obtained with commercially available solvents currently used in such applications.
Patent CA-2545102-A1 (CA)
Title: Synchronizing information across telecommunications terminals for multiple users
Inventor: ERHART GEORGE WILLIAM
IPC: H04Q7/32
Filed: 2006-04-27
Abstract: A method and apparatus are disclosed that enable the synchronization of user profile information for M users who are sharing K telecommunications terminals, wherein M and K are not necessarily equal to each other. The disclosed technique addresses the problem that occurs when multiple users share multiple terminals, in which a user that selects a particular terminal to use has to contend with the contact lists, user preferences, and call log entries that are left over from the previous user or users of the selected terminal. In accordance with the illustrative embodiment of the present invention, the user profile information is associated with and stored for each user in a group of users, in contrast to being associated with and stored for the telecommunications terminal. The user profile information comprises (i) contact information, (ii) call or message activity, and (iii) user terminal preferences.
Patent CA-2545227-A1 (CA)
Title: Process for the preparation of a composition comprising unsaturated compounds
Inventor: BRUZZESE TIBERIO
IPC: C11C1/00
Filed: 2004-11-18
Abstract: The present invention relates to a process for the preparation of a composition comprising unsaturated compounds, in particular polyunsaturated compounds, which comprises concentrating and purifying the compounds by contact with silicon and/or aluminium derivatives. The process of the invention represents an advantageous substitute of the usual distillation processes, coupled or not to chromatographic processes, and allows to isolate and remove polar byproducts.
Patent CA-2545954-A1 (CA)
Inventor: HESELHAUS ANDREAS
IPC: F01D11/12
Filed: 2004-10-12
Abstract: Layered systems in prior art are inefficient at cooling an external hot gas.  The inventive layered system (1) comprises an external porous layer (10), in which the pore walls (22) of the pores (25) have differing thicknesses. This improves the cooling action by preventing too much heat from entering the layered system (1).
Patent CA-2548655-A1 (CA)
Title: Membrane thermo-acoustique radiante
Inventor: DUCHARME ROBERT
IPC: B32B15/16
Filed: 2006-05-30
Abstract: La membrane thermo-acoustique radiante est destinée à être utilisée sur un plancher sous une unité de spas, un bain tourbillon ou thérapeutique, une ba se d'inertie et autres. La membrane comporte une couche radiante constituée d'un film métallique, sur laquelle est laminée à l'aide de bitume élastomère à chaud une couche de granulats de caoutchouc de grosseur variable à laquelle peuvent être ajoutées des composantes telles des fibres de bois, minérales, synthétiques ou végétales. La membrane est aussi composée d'une couche imperméable à l'eau, pour agir comme pare-vapeur. Cette couche faite de polyéthylène, de polypropylène, de polyester ou de métal est résistante à la déchirure, au poinçonnement statique, à la traction, a une grande capacité d'allongement et est recouverte de bitume élastomère. La couche de bitume élastomère de la couche imperméable est placée sur la couche de granulats de la couche radiante pour assembler la membrane par adhésion des couches.
Patent CA-2549901-A1 (CA)
Inventor: MASON PAUL L II
IPC: G07F9/10
Filed: 2004-11-24
Abstract: A method of controlling a vending machine, the vending machine having at least two operating modes including a normal operating mode in which items to be vended are maintained at or near a desired vend temperature and an energy saving mode (48) in which items to be vended are allowed to be at a temperature other than the desired vend temperature, the method includes collecting historical operational data about the vending machine; predicting, based at least in part on the collected historical data, at least one period of potential vend activity (46); and putting the vending machine into normal operating mode prior to any predicted period of potential vend activity (42).
Patent CA-2550312-A1 (CA)
Title: Retinal toxicity screening methods
Inventor: VERDUGO-GAZDIK MARIA EUGENIA
IPC: A61K38/12
Filed: 2004-12-13
Abstract: The present invention relates to methods for characterizing a test agent using a fluorescently detectable .alpha.v.szlig.3 and .alpha.v.beta.5 integrin specific agent and a retinal pigment epithelial cell. The invention further relates to kits having a fluorescently detectable .alpha.v.beta.3 and .alpha.v.beta.5 integrin specific agent and a retinal pigment epithelial cell.
Patent CA-2550502-A1 (CA)
Inventor: HANSEN DOUGLAS WALTER
IPC: H04R9/06
Filed: 2005-05-05
Abstract: In a first aspect, the invention provides an audio amplifier. A regulator reference signal corresponding to an input audio signal is generated by regulator reference generator. A  power signal is generated corresponding to the regulator reference signal by a voltage regulator. A compensation block also uses the input signal, or a delayed version of the input signal to generate a modulation control signal. A modulator generates a modulated signal in response to the modulation control signal. An output stage combines the power signal and the modulation signal to provide an output audio signal corresponding to the input audio signal. The compensation block may be a forward compensation block configured to compensate for characteristics of the regulator reference generator or the voltage regulator or both, and possibly other components of the amplifier. In other embodiments, the compensation block may be part of a feedback compensation loop.