baber/WOPTO huggingface dataset:
Patent DE-60318954-D1 (DE)
Inventor: KUKOLJ GEORGE
IPC: C12N15/10
Filed: 2003-10-24
Granted: 2008-03-20
Abstract: An inhibitor-resistant HCV NS3 protease is provided which is useful to screen for compounds having therapeutic value against drug resistant HCV strains. In particular, the inhibitor-resistant HCV NS3 protease comprises an amino acid sequence which is mutated in the substrate binding pocket thereof rendering the protease resistant to inhibitor. In a specific aspect of the present invention, at least one of the amino acids at position 155, 156 and 168 of the HCV NS3 protease is mutated to yield an inhibitor-resistant protease.
Patent DE-60320945-D1 (DE)
Inventor: GROS GEORGES
IPC: A23K50/15
Filed: 2003-02-12
Granted: 2008-06-26
Abstract: A process for purifying an aqueous solution to obtain purified gaseous acrolein by introducing the aqueous solution into a distillation column equipped at its base with at least one boiler and at its top with at least one condenser, withdrawing a liquid mixture essentially containing water at the base of the distillation column, withdrawing a gas essentially containing acrolein and water at the top of the distillation column, cooling the gas mixture withdrawn at the top of the distillation column in the condenser, to a temperature which makes it possible to obtain, on the one hand, an aqueous condensate and, on the other hand, an acrolein-rich gas mixture, and withdrawing the acrolein-rich gas mixture.
Patent DE-60322538-D1 (DE)
Inventor: WOOD JOHN MICHAEL
IPC: H03M1/10
Filed: 2003-06-24
Granted: 2008-09-11
Abstract: This invention relates to a method of calibrating a time-interleaved analogue-to-digital sampler ( 10 ) and to a method of performing analogue-to-digital conversion with a sampler ( 10 ) so calibrated. The invention provides a method of calibrating a sampler ( 10 ) comprising N time-interleaved ADCs ( 12 a-d), the method comprising the steps of: (a) injecting in turn N calibration signals ( 13 ) into the sampler such that each calibration signal ( 13 ) occupies one of N related frequencies; (b) determining the input signal for each one of the N calibration frequencies ( 13 ); (c) measuring in the frequency domain the output at each of the N related frequencies for each one of the N calibration frequencies; and (d) determining the relationship that relates the input signal to the output at each of the N related frequencies for each one of the N calibration frequencies.
Patent DE-60323976-D1 (DE)
Inventor: KAEMPFEN NICOLAS
IPC: A47C19/04
Filed: 2003-09-18
Granted: 2008-11-20
Abstract: The bed has stowage mechanisms (30) enabling a frame (20) to be moved from a use position to a stowed position. Each mechanism has two shafts (31) connected via a linkage arm (32) to a pivot (33) on a support structure (10). A motion synchronization mechanism causes a synchronized rotation of the shafts. Small control rods (34) on shafts form a deformable parallelogram causing a synchronized rotation of the shafts.
Patent DE-68902152-D1 (DE)
Inventor: SANTINI CONRAD
IPC: C07D401/12
Filed: 1989-02-06
Granted: 1992-08-27
Abstract: 8-(2-Pyrimidylsulfinyl)quinolines of general formula I <CHEM> or a pharmaceutically acceptable acid addition salt thereof wherein Q is hydrogen, fluoro, chloro, nitro, amino, trifluoromethyl, alkanoylamino of two to four carbon atoms, alkoxy of one to five carbon atoms, alkyl of one to five carbon atoms or dialkylamino said alkyl having one to four carbon atoms; X is hydrogen, alkyl of one to five carbon atoms or alkoxy of one to five carbon atoms; Y is hydrogen, fluoro, chloro, bromo, alkoxy of one to five carbon atoms or alkyl of one to five carbon atoms; Z is hydrogen, alkyl of one to five carbon atoms, alkoxy of one to five carbon atoms, phenoxy, benzyloxy, cycloalkyloxy of five to seven carbon atoms, amino, alkylamino having one to four carbon atoms, dialkylamino said alkyl having one to four carbon atoms, anilino, N-alkylanilino said alkyl having one to four carbon atoms, benzylamino, N-alkylbenzylamino said alkyl having one to four carbon atoms, morpholino, piperidino or pyrrolidino; and n is 1, are inhibitors of the H<+>/K<+> ATPase system and are useful in the treatment of ulcers.
Patent DE-68921076-D1 (DE)
Inventor: LAMARRE BRUCE
IPC: B01D19/00
Filed: 1989-10-12
Granted: 1995-03-23
Abstract: A method for removing hazardous contaminants such as radon gas and volatile synthetic organic chemicals from domestic water supplies uses a perforated, horizontally-oriented tray which is baffled to define a curved (e.g., serpentine, spiral) liquid flow path. Contaminated water is distributed upon a portion of the tray and flows as directed by the baffles to a downcomer and into a storage tank. Air is blown into the storage tank, which is located below the perforated tray, and up through the perforations. The forced air causes the water flowing across the tray to froth, and evaporates the contaminants out of the frothing water. The forced air, carrying the volatilized contaminants, is then vented outside the home. <IMAGE>
Patent DE-69002362-D1 (DE)
Inventor: NAVASCUES LUC ETIENNE ANDRE
IPC: C05G3/30
Filed: 1990-03-13
Granted: 1993-09-02
Abstract: Anticaking compositions for fertilisers, of improved efficiency, assaying at 1 to 30 % of fatty amines in which the length of the aliphatic chains is distributed around 17.5 carbon atoms with a coefficient of variation which is characteristically greater than or equal to 2. High-performance anticaking agents are easily produced according to the conventional types of coating agents, fluxes or amine fillers, by being formulated with the aid of mixtures of industrial amines originating from natural fatty acids, deliberately combined to conform to this characteristic, or with the aid of synthetic fatty acids originating from the oxidation of normal paraffins.
Patent DE-69003061-D1 (DE)
Inventor: SHIMAZAKI YUKIO
IPC: A61K47/42
Filed: 1990-09-20
Granted: 1993-10-07
Abstract: Aqueous protein-containing solutions, in which a protein is dissolved at a high concentration at a pH near the isoelectric point of the protein by adding an anionic polymer or a salt thereof to the solution. Pharmaceutical formulations using a physiologically active protein are prepared using this technique.
Patent DE-69005781-D1 (DE)
Inventor: VAN DER WAAL NL- BP DELFZIJL I
IPC: B09B3/00
Filed: 1990-10-19
Granted: 1994-02-17
Abstract: Method for separating contaminants from soil by leading the contaminated soil through separating apparatus, in which the contaminant in the form of particles having a specific weight different from that of the soil is separated from the earth in a spiral separator (4).
Patent DE-69006372-D1 (DE)
Inventor: CLUNIAT CLAUDE
IPC: H01Q1/12
Filed: 1990-02-09
Granted: 1994-03-17
Abstract: The antenna system consists of a parabolic reflector (1) associated with source means (2, 3), the reflector being positioned and held by means of a support foot formed from a hollow tubular body (7) fixed at its upper part to the rear central zone of the reflector and hinged at its lower part on a base about a horizontal axis (XX) in order to define the elevation of the antenna. The base comprises a part (24) which is movable in rotation in order to define the azimuth of the antenna. The tubular body (7) of the support foot has a sufficient cross-section to contain all the circuits associated with the antenna. Application, in particular to satellite reception, of which the radiated powers are greater than 50 dBW. <IMAGE>
Patent DE-69010939-D1 (DE)
Inventor: EBERLE JEAN-MARIE
IPC: B31B50/28
Filed: 1990-03-06
Granted: 1994-09-01
Abstract: The method is characterised in that it consists in unrolling at least two strips intended to form the component parts (2, 3) of the first layer of the body (1), in shaping them and placing them in such a way that they are joining without overlapping, then in unrolling at least two strips intended to form the component parts (4, 5) of the second layer of the body (1), in shaping them and in positioning them in such way that they are also joining without overlapping, these operations to be continued, if necessary, depending on the number of layers provided, the joints, (6, 7) of the strips of each possible additional layer being substantially offset with respect to those of the strips of the preceding layer, and finally in cutting off and removing the packing body (1). <IMAGE>
Patent DE-69011657-D1 (DE)
Inventor: BURROWS CHRISTOPHER B
IPC: A23L19/18
Filed: 1990-06-20
Granted: 1994-09-22
Abstract: A method for producing french fried potato strips which includes washing and cutting raw potatoes into suitably sized strips. The raw potato strips are steam blanched, immersed in a hot brine solution, partially dehydrated in hot air, par fried in oil, and then frozen. After par frying, the strips have a solids content of about 20 to 45 percent by weight. The frozen french fries are reconstituted by finish frying, and have a sodium chloride content of about 0.5 to 2 percent by weight.
Patent DE-69028855-D1 (DE)
Inventor: SPIELVOGEL BERNARD F
IPC: C12Q1/68
Filed: 1990-11-29
Granted: 1996-11-14
Abstract: Disclosed are oligonucleoside boranophosphates, or salts thereof, comprising a chain of natural or modified ribonucleotides or deoxyribonucleotides, containing at least one boronated internucleotide phospodiester linkage of the formula:    <IMAGE>  (III)  W is selected from the group consisting of =O, =S, -OPr, and -SPr where Pr is a base-labile protecting group. X is selected from the group consisting of -BH3, -BH2R1, -BHR1R2 and -BR1R2R3. R1 is selected from the group consisting of -R4, -COOH, -COOR4, -CONHR4, -CON(R4)2, -CN+R4Z-, wherein Z- is an anion, -CN, carboxycholesteryl and carboxybenzyl, wherein R4 is C1 to C18 alkyl. R2 is selected from the group consisting of -R5, -COOH, -COOR5, -CONHR5, -CON(R5)2, -CN+R5Z-, wherein Z- is an anion, -CN, carboxy- cholesteryl and carboxybenzyl, wherein R5 is C1 to C18 alkyl. R3 is selected from the group consisting of C1 to C3 alkyl. Most preferably, X is -BH3 and W is =0. Compounds of Formula (III) are useful as antisense agents and probes in molecular biology, and have pharmacological activities including anti-inflammatory, antihyperlipidemic, and antineoplastic activity.
Patent DE-69029978-D1 (DE)
Inventor: GRAZIANO KAREN ANN
IPC: H01L21/027
Filed: 1990-06-27
Granted: 1997-04-03
Abstract: Melamine-containing photoresists are disclosed that display increased sensitivity, measured as lithographic potential, when compared to known photoresists that contain melamine resin as a crosslinker. The melamine resin in these photoresists contains a higher percent, by weight, of monomeric hexamethoxymethylmelamine than in known resists.
Patent DE-69112827-D1 (DE)
Inventor: JENKINS WALTER
IPC: C23C4/12
Filed: 1991-04-18
Granted: 1995-10-12
Abstract: PCT No. PCT/GB91/00606 Sec. 371 Date Nov. 12, 1992 Sec. 102(e) Date Nov. 12, 1992 PCT Filed Apr. 18, 1991 PCT Pub. No. WO91/16471 PCT Pub. Date Oct. 31, 1991.A method for the spray distribution of metals includes emitting a stream of molten metal particles and a gas nozzle which is rotated about the stream. The gas nozzle is inclined to the axis of the particle stream and in the direction of the stream in order to produce a required distribution of the particle stream on a workpiece.
Patent DE-69114275-D1 (DE)
Inventor: GERENTES DENISE
IPC: C12N15/82
Filed: 1991-03-01
Granted: 1995-12-07
Abstract: A method for transforming plant cells of the species Beta vulgaris, wherein a dispersion or a suspension of crumbly white calluses is contacted with Agrobacterium containing a vector carrying a gene intended for insertion into the plant cells, followed by the coculture of the plant cells and the bacteria to produce transformed crumbly calluses, which are then regenerated into transgenic plants. Transgenic plants are also described which belong to the species Beta vulgaris and are resistant to infection by the beet necrotic yellow vein virus (BNYVV), said plants being stably transformed by a nucleic acid fragment which codes for at least a part of the capsid protein of BNYVV or for a derivative thereof.
Patent DE-69114630-D1 (DE)
Inventor: PELLON BRIAN JAY
IPC: C08F110/06
Filed: 1991-09-06
Granted: 1995-12-21
Abstract: An elastomeric high molecular weight substantially amorphous propylene homopolymer having a melting point between about 145 DEG C and 165 DEG C, a melt viscosity at 190 DEG C greater than 200,000 cps and a heat of fusion between about 4 cal./gm. and about 10 cal./gm.is disclosed. The polymer comprises from about 35% to about 55% of a diethyl ether soluble fraction, the fraction having an inherent viscosity less than about 1.0 dl/g and exhibiting substantially no isotactic crystallinity and from about 30% to about 70% of a heptane soluble fraction, the fraction having a melting point between about 100 DEG C and 115 DEG C and a heat of fusion less than about 2.0 cal./gm.
Patent DE-69114934-D1 (DE)
Inventor: DAIGLE RONALD E
IPC: G01S7/52
Filed: 1991-07-18
Granted: 1996-01-11
Abstract: An ultrasonic diagnostic imaging system is provided for scanning with a linear transducer array and displaying an image area which is truncated with respect to a conventional triangular image sector to take the form of a trapezoid. Uniformity of image resolution and ease of signal processing enhancement is provided by transmitting adjacent ultrasonic beams at equal angular increments over the sector area. The ultrasonic beams transmitted are focused around predetermined transmit focal points and the transmit aperture employed for each transmission is determined by a transducer sensitivity criterion applied to the focal point. Means are provided for delaying signal components received from the beam directions so that the sum of the components will form a coherent echo signal. Means are provided for dynamically focusing received signal components by dynamically focusing received signal components by dynamically varying the sampling frequencies of laterally disposed signal components, and the receive aperture is dynamically varied in correspondence with the number of array elements which satisfy a sensitivity criterion at different depths of field. <IMAGE>
Patent DE-69115297-D1 (DE)
Inventor: DJURIC STEVAN
IPC: A61K31/00
Filed: 1991-06-27
Granted: 1996-01-18
Abstract: This invention relates to compounds of Formula I and the stereoisomers and pharmaceutically acceptable salts thereof    <IMAGE>  +TR   <IMAGE>   wherein R is alkyl, alkenyl, alkynyl, or cycloalkylalkyl; R1 is alkyl; R2 is hydrogen, alkyl; R6 is alkyl; n is 1 to 5; p is 0 to 6; x is 0 or 2; and R4 and R5 are independently hydrogen or alkyl or together with N form a cycloalkylamine. The compounds of Formula I are leukotriene B4 antagonists and are useful as anti-inflammatory agents and in treating disease conditions mediated by LTB4.
Patent DE-69115525-D1 (DE)
Inventor: ENDO TAKESHI
IPC: C07F7/18
Filed: 1991-03-01
Granted: 1996-02-01
Abstract: A novel tri-substituted triphenyl isocyanurate is defined by the following formula and useful as a crossliking agent for resin. <CHEM> wherein X represents -O- or -COO-; and R represents a hydrogen atom, a straight-chain or branched alkyl group having 1 to 10 carbon atoms which may be either unsubstituted or substituted with a hydroxyl group, an aryl group or an R'3Si group (wherein a plurality of R' groups may be the same or different from each other and each represent a straight-chain or branched alkyl group having 1 to 10 carbon atoms or a phenyl group), excepting the case wherein X is -O- and R is CH3.
Patent DE-69123810-D1 (DE)
Inventor: ROGERS EDWARD J
IPC: H01H9/00
Filed: 1991-09-24
Granted: 1997-02-06
Abstract: An arrangement is provided that includes a coordinating input (e.g., via 62 to 64 to 54) for a mechanism (18) of an interrupter switch (10); the coordinating input being derived from sensed movement of an element (e.g., 32) away from a first position (FIGS. 3 and 4) and toward a second position (direction 67). The coordinating input is utilized to trip the interrupters if they are closed. In a specific arrangement, a stored-energy mechanism (18) is tripped to provide opening and closing of the interrupters via a high-speed interrupter drive train (20). The tripping arrangement (34) is operable via a first input (at 56 via 58,60) to cause movement of a latch member (40) to release the stored-energy mechanism (18) to operate the interrupter drive train (20). The first input may be actuated via open or close instructions, including both local and remote capabilities. The latch (40) for the stored-energy mechanism ( 18) is reset after each actuation. An output shaft (19) of the mechanism is connected to drive the interrupter drive train (20). Both opening and closing are accomplished via rotation of the output shaft (19) in the same direction. An open/close sensing input for the interrupter drive train (20) is derived from the position of the output shaft (19). In a specific embodiment, the sensed movement of the element (32) corresponds to the movement of a disconnect linkage (22) away from a closed position. <IMAGE>
Patent DE-69128479-D1 (DE)
Inventor: MERRIFIELD ROBERT
IPC: A61K38/00
Filed: 1991-08-08
Granted: 1998-01-29
Abstract: Glucagon analogs characterized principally by the removal of the 9-aspartic acid residue or its replacement with an amino acid residue other than an L- dibasic amino acid containing up to five carbon atoms with or without a histidine at the amino terminal are useful adjuncts to insulin therapy.
Patent DE-69129869-D1 (DE)
Inventor: VEENSTRA ANNEMARIE EVELINE
IPC: C12R1/82
Filed: 1991-02-27
Granted: 1998-09-03
Abstract: Novel methods and compositions are provided for the enhanced production of fermentable or known and new  beta -lactam antibiotics. The process is exemplified by the production of penicillin. In addition, the P.chrysogenum and A.chrysogenum  delta -(L- alpha -aminoadipyl)-L-cysteinyl-D-valine synthetase genes have been isolated and sequenced. Also methods are provided for the production of  delta -(L- alpha -aminoadipyl)-L-cysteinyl-D-valine synthetase using recombined DNA techniques.
Patent DE-69131113-D1 (DE)
Inventor: SATO KOICHI
IPC: C08F20/30
Filed: 1991-06-28
Granted: 1999-05-20
Abstract: Provided is a liquid crystal copolymer compound having a repeating unit represented by the formula <CHEM> wherein A represents a polymeric main chain of a carbon type; and B represents a polyoxyalkylene group or <CHEM>  wherein D represents <CHEM> or b and c each representing an integer of 0 to 20; R represents an alkyl group, a phenyl group, a siloxy group or a polysiloxy group; R' represents an alkyl group or a phenyl group; and a represents an integer of 0 to 50. <IMAGE>
Patent DE-69132091-D1 (DE)
Inventor: ALBINSON FREDERICK DAVID
IPC: C07D209/16
Filed: 1991-06-20
Granted: 2000-05-11
Abstract: A method for the preparation of 3-(2-aminoethyl)-N-methyl-1H-indole-5-methanesulphonamide by reaction of 4-hydrazino-N-methylbenzenemethanesulphonamide and 4-chloro-1-hydroxybutanesulphonic acid, sodium salt in the presence of an acid.
Patent DE-69133345-D1 (DE)
Inventor: PAYNE JEWEL M
IPC: A01N63/23
Filed: 1991-10-11
Granted: 2004-01-22
Abstract: A toxin, active against dipteran pests, is available in a microbe of the species Bacillus thuringiensis identified as PS201T6, having the NRRL accession number B-18750.
Patent DE-69201266-D1 (DE)
Inventor: FARINA FELICE
IPC: A01J5/02
Filed: 1992-05-14
Granted: 1995-03-09
Abstract: An apparatus (1) for automatically washing teats of generic dairy animals, specifically dairy cattle, comprises a box-type body (2) formed with an opening for introducing a teat (T) thereinto, and two pairs (6 and 7) of counter-rotating brushes located at the opening in the box-type body and aligned along a direction of introduction (V) of the teat (T) into the box-type body. <IMAGE>
Patent DE-69203424-D1 (DE)
Inventor: GEHLERT DONALD RICHARD
IPC: A61P13/00
Filed: 1992-09-24
Granted: 1995-08-17
Abstract: This invention provides N-alkyl-3-phenyl-3-(2-substituted phenoxy)propylamines which are useful to treat neurological disorders associated with norepinephrine imbalance.
Patent DE-69204880-D1 (DE)
Inventor: SEEMANN MICHEL
IPC: A01B63/24
Filed: 1992-03-24
Granted: 1995-10-26
Abstract: The invention relates to an agricultural soil-working machine. According to the invention, the agricultural soil-working machine is characterised in that at least one guide member (33, 34) has a V-shaped or equivalent positioning surface intended for cooperating with a complementary positioning surface provided on the coulter arm (6), so that, during work, said guide member (36) positions said coulter arm (6) transversely to the working direction (5). <IMAGE>
Patent DE-69212811-D1 (DE)
Inventor: KUC JOHN
IPC: C08J11/06
Filed: 1992-05-12
Granted: 1996-09-19
Abstract: Waste or scrap rubber is converted into a mouldable, thermoplastic resin product by the steps of mixing the vulcanised rubber (12) with a heated heavy paraffin distillate (16) on a conveyor (20). Feeding the mixture on the conveyor (20) through a heating chamber (22). Adding to the heated mixture a particulate thermoplastic scrap material (24). Masticating the mixture comprising the paraffin treated rubber and the thermoplastic material in a masticator (30) and extruding (32) and pelletising the masticated product. <IMAGE>
Patent DE-69215277-D1 (DE)
Inventor: HAASCH JAMES THOMAS
IPC: F28D1/053
Filed: 1992-06-02
Granted: 1997-01-02
Abstract: Difficulty in heat exchanger module replacement and the cost of plural manifolds in a modular heat exchanger useful in heavy duty vehicles or the like is avoided in a construction that includes an elongated manifold (20) having spaced interior inlet and outlet channels (84, 86) along with a plurality of spaced inlet and outlet ports (68, 70) in fluid communication with respective ones of the inlet and outlet channels (84, 86). An elongated frame member (14) is spaced from and parallel to the manifold (22) and has a plurality of spaced retaining formations (42). A plurality of heat exchanger modules (12) are mounted between the frame member (14) and the manifold (20) in side by side relation and each module has spaced tanks (34, 36; 50, 52) with a plurality of finned tubes (30, 32) extending between and in fluid communication therewith. One tank (34, 36) has a mating retaining formation (40) for receipt within the retaining formation (42) in the frame member (14) while the other tank (50, 52) has inlet and outlet ports (62, 64) aligned with and in fluid communication with corresponding inlet and outlet ports (68 and 70) in the manifold (20). A baffle (60) is disposed in the tank (50, 52) between the inlet and outlet ports (62, 64) thereof. <IMAGE>
Patent DE-69219290-D1 (DE)
Inventor: CHOPIN THIERRY
IPC: A61K8/30
Filed: 1992-10-28
Granted: 1997-05-28
Abstract: A rare earth sesquisulphide of formula M2S3 has an interstitial structure (in which M is an element from the lanthanide gp. or yttrium, and contg. an alkaline earth element as a dopant). At least part of the latter is included in the crystal lattice of the sulphide, and the material is in the form of a powder of average particle size 0.2-5 microns. Also claimed are their prepn..
Patent DE-69220965-D1 (DE)
Inventor: STIMPSON PHILIP
IPC: B06B1/02
Filed: 1992-11-12
Granted: 1997-08-21
Abstract: PCT No. PCT/GB92/02098 Sec. 371 Date May 10, 1994 Sec. 102(e) Date May 10, 1994 PCT Filed Nov. 12, 1992 PCT Pub. No. WO93/09881 PCT Pub. Date May 27, 1993A nebulizer for use in administering a medicament to a patient undergoing treatment for example, comprises an ultrasonic piezo-electric transducer (60) and a transducer drive system (D) which is caused to drive said transducer at or near its anti-resonant frequency. There is also provided means to optimize nebulized fluid particle size and transfer to the patients lungs for example, by operating at an anti-resonant frequency in the range of 1.36 to 1.56 MHz and having a single outlet baffle and relatively short outlet tube (24) arrangement.