baber/WOPTO huggingface dataset:
Patent AT-E251132-T1 (AT)
Inventor: BROWN JACK D
IPC: B01J31/02
Filed: 1999-06-24
Granted: 2003-10-15
Abstract: The present invention provides methods for preparing S-aryl cysteines in enantiomeric excess of greater than about 96%. Specifically, the present invention provides enantioselective methods for preparing S-aryl cysteines starting from cystine, cysteine or a serine.
Patent AT-E422067-T1 (AT)
Inventor: KAELIN LAURENT
IPC: G04B19/30
Filed: 1999-10-19
Granted: 2009-02-15
Abstract: A watchcase (1) has battery compartment and battery(5,6), an electronic circuit delivering pulses (15), hands (12) and watchglass (4). The watch dial is illuminated by an electroluminescent ring which is secured to the watchglass heel (17) by a pressed fit translucent ring (19) and has tabs which make contact with elastic electrical connections (33,34) from the pulsing circuit
Patent AT-E253210-T1 (AT)
Inventor: MEIER MAIK
IPC: C21B5/00
Filed: 1999-12-10
Granted: 2003-11-15
Abstract: Solid particle injection into a shaft furnace uses high pressure gas introduction to increase carrier gas flow velocity and cause particle spiral motion towards a lance outlet.  Solid particles are injected into a shaft furnace by entrainment in a carrier gas stream through an injection lance into the hot blast in a tuyere, a higher pressure gaseous medium being introduced into the carrier gas stream, immediately prior to entry into the lance, to increase the flow velocity and cause spiral motion of the particles towards the lance outlet. An Independent claim is also included for equipment for carrying out the above process.
Patent AT-E273948-T1 (AT)
Inventor: MINCHER DAVID JOHN
IPC: C07D295/10
Filed: 1999-06-16
Granted: 2004-09-15
Abstract: A compound is provided having the formula: wherein R<1 >and R<2 >are independently hydrogen, hydroxy, alkoxy or acyloxy R<3 >and R<4 >are independently oxo, hydroxy or hydrogen; one of R<5 >or R<6 >is -A-B and the other is hydrogen, hydroxy, alkoxy, acyloxy, a group -A-B or a group -amino-R<7>-O-Y; the or each A is independently a spacer group having the formula -amino-R<7>-O- which is bonded to the anthracene ring via the amino group nitrogen and to B via the -O- atom R<7 >is a divalent organic radical; B is an amino acid residue, a peptide group, or isostere thereof; and Y is hydrogen or a capping group, or a physiologically acceptable derivative thereof. The compounds primarily have utility against cancers, but also have use against viruses and parasites having topoisomerases.
Patent AT-E429066-T1 (AT)
Inventor: FREBEL FABRICE
IPC: H02M3/335
Filed: 1999-07-27
Granted: 2009-05-15
Abstract: The converter comprises a transformer with a primary winding (1), a secondary winding (2) and a switching regulator (S). A tertiary winding (3) is connected in series with a first diode (D1) and a second diode. The primary and tertiary winding are wound in the same direction. A capacitor (C) is connect from the junction of first diode and second diodes to the junction of the primary and the switching regulator.
Patent AT-E252825-T1 (AT)
Inventor: HESS JOHN R
IPC: G01N33/48
Filed: 1999-08-30
Granted: 2003-11-15
Abstract: Novel additive solutions useful for the storage of human red blood cells (RBCs) under refrigerated conditions are disclosed. Also disclosed is a method of using the additive solutions in an appropriate volume to preserve RBCs at about 1 to 6  DEG C for up to 10 weeks. Additive solutions and processes in accordance with the present invention allow the viable storage of human RBCs for an extended period of time in a solution which is directly infusible in humans.
Patent AT-E282449-T1 (AT)
Inventor: BRUNEL MARC
IPC: A61M5/28
Filed: 1999-09-30
Granted: 2004-12-15
Abstract: The invention relates to an injection device comprising a syringe body (1), which delimits a chamber which is designed to be filled with liquid, and a unit (25) for distributing the liquid, comprising an end piece for closing off the said chamber, which is extended by a base, which supports an injection needle which is protected by a protective cap (35), the said distribution unit being mobile axially between a closing-off position of the chamber, and a position for injection of the liquid. According to the invention, the unit (25) for distributing comprises an intermediate section (31) between the base and the closing-off end piece, and the syringe body (1) comprises a ring (6) which delimits two superimposed compartments (18, 19), which can each accommodate the said intermediate section. In addition, the protective cap (35) and this intermediate section (31) have complementary profiles (34, 38) in the form of a cam, which can permit generation of axial displacement of the unit (25) for distributing, towards its injection position, during rotation of the said protective cap.
Patent AT-E256501-T1 (AT)
Inventor: FOUILLET YVES
IPC: G01N31/22
Filed: 1999-10-14
Granted: 2004-01-15
Abstract: Chemical and/or biological analysis device comprising an analysis support (100) with at least one input bowl (102) to contain a sample, at least one output bowl (104) to output the said sample, at least one internal duct (108) passing through the support to form a connection between the input bowl and the output bowl, and at least one reagent reservoir (120a, 120b, 120c) connected to each duct (108) between the input bowl and the output bowl, in which the input bowl, the output bowl and the reservoir open up onto a first face (106) of the analysis support.
Patent AT-E245481-T1 (AT)
Inventor: BURCHELL TIMOTHY D
IPC: B01D53/04
Filed: 1999-09-10
Granted: 2003-08-15
Abstract: A carbon fiber carbon matrix hybrid adsorbent monolith with enhanced thermal conductivity for storing and releasing gas through adsorption and desorption is disclosed. The heat of adsorption of the gas species being adsorbed is sufficiently large to cause hybrid monolith heating during adsorption and hybrid monolith cooling during desorption which significantly reduces the storage capacity of the hybrid monolith, or efficiency and economics of a gas separation process. The extent of this phenomenon depends, to a large extent, on the thermal conductivity of the adsorbent hybrid monolith. This invention is a hybrid version of a carbon fiber monolith, which offers significant enhancements to thermal conductivity and potential for improved gas separation and storage systems.
Patent AT-E349814-T1 (AT)
Inventor: BUTLER BRIAN K
IPC: H04B1/707
Filed: 1999-10-12
Granted: 2007-01-15
Abstract: A novel and improved method for performing paging is described. In one embodiment of the invention a searcher is used to detect spread spectrum signals. Samples received RF signals are stored in a sample buffer. During standby mode, the samples are gathered during paging slots assigned to the mobile. A set of searches are performed on the samples, and if pilot signals are detected additional demodulation is performed to detect paging messages. The resulting set of demodulation data may be combined to increase detection. After a page message has been detected, additional demodulation resources may be activated to processes more complete page messages, or other information channels. In one embodiment of the invention, the searcher includes a demodulator to perform quick page detection without the use of finger elements to reduce idle mode power consumption.
Patent AT-E320664-T1 (AT)
Inventor: LEISTEN OLIVER PAUL
IPC: H01Q1/38
Filed: 1999-11-19
Granted: 2006-04-15
Abstract: A dielectric-loaded antenna for circularly polarized radiation has a generally cylindrical solid dielectric body with a relative dielectric constant greater than 5, upon which body is plated a conductive sleeve encircling the body and a conductive end layer which, together with the body, form an open-ended cavity substantially filled with the ceramic material of the body. The electrical length of the cavity rim is a whole number of guide wavelengths corresponding to the antenna operating frequency less than 5 GHz. A rotating standing wave is excited around the cavity rim by a feeder structure including two helical conductor tracks on the cylindrical surface of the body which are coupled between the cavity rim and a coaxial feeder passing axially through the body.
Patent AT-E247906-T1 (AT)
Inventor: STEINBACH ORTWIN
IPC: A21D13/00
Filed: 1999-11-16
Granted: 2003-09-15
Abstract: The invention relates to a sandwich consisting of two toasted slices of bread and an edible filling placed between said slices. According to the invention, the filling is essentially arranged in the inner region of the surfaces of the slices of bread and the slices of bread are pressed together in a peripheral edge area with greater force than in the inner region so that the slices of bread adhere to each other and form a cohesive sandwich arrangement, whereby the filling is packed between the slices of bread. The invention also relates to a method for the production of a toasted sandwich that consists of two slices of bread and an edible filling placed between said slices. According to the invention, the filling is initially and essentially arranged in the inner region of the surface of a first underlying slice of bread. A second slice of bread is subsequently placed thereon. The sandwich arrangement is pressed together in an edge area with greater force than in the inner region under the effect of heating, whereby the slices of bread and the filling placed therebetween form a cohesive sandwich arrangement whose peripheral edge areas are closed. The invention further relates to a device for the production of an inventive sandwich.
Patent AT-E218692-T1 (AT)
Inventor: WITT MICHAEL T
IPC: F24J2/52
Filed: 1999-08-06
Granted: 2002-06-15
Abstract: An installation for producing solar thermal energy includes a floating thermal storage water heater provided with an absorber layer on the inside thereof and with transparent thermal insulation on the upper surface thereof. Solar rays penetrate the transparent thermal insulation and are converted into heat in the absorber layer. Heat is used to warm the water in the thermal storage water heater. The heated water can be removed in the form of a heat-carrying fluid and can, for instance, be used to provide electricity and drinking water using a steam generator, a turbo group and a condenser. Water that flows back out of the steam generator can initially be directed into a warm water recirculation heater in order to minimize heat loss. The thermal storage water heater is embedded in the warm water recirculation heater. Preferably, both storage devices are designed in such a way that their volumes can be modified.
Patent DE-1199391-T1 (DE)
Inventor: TANAKA YOSHIHIRO
IPC: B65H69/00
Filed: 2001-05-03
Abstract: Provided are a sample warper and a warping method where data regarding yarn diameters of counts are preliminarily input and stored, counts of warping yarns as well as pattern data for warping are input, a conveyor belt feed pitch per revolution of a yarn introduction means is calculated with a warping width, the number of warping yarns, and a warping length (the number of warping windings), and the conveyor belt feed pitch per revolution of the yarn introduction means is controlled according to the counts (yarn thicknesses or yarn diameters). Accordingly, a surface of the yarns wound on a warper drum is finished in a flat state without undulation irrespective of the counts, thereby solving troubles in the next weaving step.
Patent DE-03290160-T1 (DE)
Inventor: DEVILLE ANTOINE
IPC: A01G3/02
Filed: 2003-01-22
Abstract: The secateurs have a blade (2) on a bisected face (6) for transverse cutting. It has a first zone (10) at a first angle with a flat surface of the blade and a second zone (11) at a smaller angle than the first. The value of the second angle is a minimum at the region (12) adjacent to the shoulder (7) and at maximum in region (13) adjacent to the blade point.
Patent DE-05011213-T1 (DE)
Title: Analgetisch wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
Inventor: REDER F
IPC: A61K9/70
Filed: 1998-02-24
Abstract: Verwendung
einer Polymermatrixschicht, umfassend Buprenorphin oder ein pharmazeutisch akzeptables
Salz davon, und eine Stützschicht,
die aus einem pharmazeutisch akzeptablen Material gefertigt ist,
und welche für
Buprenorphin undurchlässig
ist, bei der Herstellung eines transdermalen Abgabesystems für Buprenorphin,
welches für
die Behandlung von Schmerzen in einem menschlichen Patienten für ein Dosierintervall
von mindestens vier Tagen wirksam ist, wobei das transdermale Abgabesystem
durch Aufbringen des transdermalen Abgabesystems auf die Haut eines
Patienten eine Freisetzungsrate an Buprenorphin über ungefähr ein 72 Stunden Dosierintervall
bereitstellt, so dass eine maximale Plasmakonzentration von 20 pg/ml
bis 850 pg/ml erreicht wird und die transdermale Abgabeeinheit,
wenn sie auf der Haut des Patienten für ein zusätzliches 24 Stunden Intervall
beibehalten wird, Plasmakonzentrationen an Buprenorphin in den Patienten
oberhalb der minimalen wirksamen Konzentrationen an Buprenorphin
bereitstellt, so dass die Patienten während dieses zusätzlichen
Dosierintervalls weiterhin wirksames Schmerzmanagement erfahren.
Patent DE-382593-T1 (DE)
IPC: B29C65/34
Filed: 1990-01-23
Abstract: A welding seal assembly for use in joining and sealing two telescoped tubular elements in a lap joint, specifically a tubular pipe in a pipe socket formed in a pipe fitting. The seal assembly comprises a thermoplastic welding sleeve with an embedded electric heating coil for fitting between the pipe and the socket; a mounting collar including a ring-like body that is fitted over the pipe and against the end of the socket element with a thin-walled, compressible flange extending from the body over the outer side of the socket element and overlying the overlapped elements of the joint; an electrical connector in a radially projecting tab on the ring, including electrical contacts connected to the leads of the heating coil; and a clamp ring surrounding the compressible flange and held captive thereon between the tab on the body and detents on the flange. The clamp ring has an outwardly offset section on one side providing generally radial walls that are squeezed together to contract the clamp ring and compress the flange around the joint. The collar, flange and socket tab are injection-molded with the welding sleeve and the embedded coil as mold inserts, and the end of the welding sleeve is bonded to the collar in the molding process.
Patent ES-2428439-T1 (ES)
Title: Un procedimiento para la preparación de Ramipril
Inventor: DESAI PARIMAL
IPC: C07C231/18
Filed: 2011-04-05
Abstract: Un proceso para la síntesis enantioespecífica del ácido (2S)-acetilamino-3-(2-oxociclopentil)propiónicode fórmula (I) ópticamente puro que comprende:**Fórmula** hidrolizar una mezcla estereoisomérica de 2-(acetilamino)-3-(2-oxociclopentil)propanoato de alquilo C1-4 de fórmula(II), en la que R es alquilo C1-4,**Fórmula** con una enzima serina endopeptidasa alcalina, formando una mezcla del isómero (+) ácido (2S)-acetilamino-3-(2-oxociclopentil)propiónico (I) y el isómero (-) (2R)-2-(acetilamino)-3-(2-oxociclopentil)propanoato de alquilo C1-4 (III) **Fórmula**
Patent ES-2032368-T1 (ES)
Title: Dispositivo de retencion de cinturon de seguridad para vehiculos.
IPC: B60R22/28
Filed: 1990-11-26
Abstract: EL SISTEMA DE RESPALDO TECNICO Y CINTURON DE SEGURIDAD PARA VEHICULOS ESTA PROVISTO DE UN ENROLLADOR DE CINTURON (10) AUTOBLOCANTE SENSIBLE AL VEHICULO Y/O A LA BANDA DEL CINTURON. PARA CONSEGUIR UN RAPIDO ACCIONAMIENTO DEL DISPOSITIVO DE APRIETE DEL CINTURON (12) CON UN TIRON MINIMO Y PRESERVAR DEL DETERIORO A LA BANDA DEL CINTURON A CAUSA DEL AGARROTAMIENTO, SE ENCUENTRA LIMITADA A UN VALOR PREFIJADO LA FUERZA DE ESCAPE DEL DISPOSITIVO DE APRIETE DE LA BANDA (12) EJERCIDA SOBRE EL CINTURON (28) MEDIANTE UN BUEN DIMENSIONADO Y CONFIGURADO DEL SISTEMA, CON LO QUE EL DISPOSITIVO DE APRIETE (12) NO CAUSA NINGUN DEBILITAMIENTO NOTABLE DEL CINTUON (28). EL ENROLLADOR DE CINTURON (10) ESTA DIMENSIONADO POR SU PARTE PARA, AL MENOS, RECIBIR LAS FUERZAS EXCEDENTES ESPERADAS EN CASO DE ACCIDENTE, INICIADAS A TRAVES DEL CINTURON (28) Y DEL VALOR PREFIJADO, ESPERADAS EN CASO DE ACCIDENTE, DE MODO QUE PUEDE ACOGER EL PESO BLOQUEADOR EN CASO DE EXCEDER ESTE VALOR PREFIJADO CUANDO, POR EJEMPLO, SE DESLIZA EL DISPOSITIVO DE APRIETE DEL MISMO.
Patent ES-2051655-T1 (ES)
Inventor: MAY EWALD DIPL-ING
IPC: F16F9/32
Filed: 1992-02-26
Abstract: A shock-absorber piston (13) which consists of two piston halves (14, 15; 19, 20; 23, 24) or of two piston halves (14, 15; 19, 20; 23, 24) and a sleeve (25) which is arranged in the centre, these being firmly connected to one another, and in the case of which the holes (17, 17') on the annular-chamber side for accommodating the piston rod are not located in a sleeve (4), and in the case of which the supports, which are located in the form of an annulus around the piston rod, for the valve spring discs are always located precisely at the level of the plane of the annular chamber bases (12). <IMAGE>
Patent ES-2063725-T1 (ES)
Inventor: BERTHON FRANCIS
IPC: E02D29/14
Filed: 1992-03-24
Abstract: The device comprises a frame (1) and a removable grating (2) which is hinged along an axis X-X of the frame, which grating consists of a series of bars connected in pairs, by at least one tie and running perpendicularly to the hinge axis X-X of the grating (2). The grating (2) furthermore comprises two intermediate bars (19A, 19B) connected to the other bars of the grating by their ends opposite the hinge axis X-X and the free ends of which interact, by elastic bending of the bars (19A, 19B) in the plane of the grating, with means (13, 14), arranged on the frame (1), for holding the grating (2) in the open and closed position. <IMAGE>
Patent ES-2073389-T1 (ES)
Inventor: BERAN MARK
IPC: E05F15/603
Filed: 1994-07-14
Abstract: Apparatus is are disclosed for selective alteration and control of door movement modes, the apparatus being primarily non-hydraulic and incorporated with a known mechanism which is functional independently from the apparatus in one mode of operation and which includes a piston for controlling door closing characteristics by selected fluid flow within the mechanism. The apparatus includes a motor driven lead screw having a linearly movable shuttle unit mounted thereon, the shuttle unit being positioned relative to the piston of the mechanism to accommodate nonattached contact with the piston to urge the piston, when the shuttle unit is moved, in a direction that will at least provide selective assistance with door opening in another mode of operation.
Patent ES-2131037-T1 (ES)
Title: Metodo de produccion de lovastatina.
Inventor: DIMOV DIMCHO IVANOV
IPC: C07D309/30
Filed: 1996-10-22
Abstract: LA INVENCION SE REFIERE A UN METODO DE APLICACION EN LA INDUSTRIA FARMACEUTICA. DE ACUERDO CON ESTE METODO, LA LOVASTATINA SE OBTIENE A PARTIR DE UN CALDO DE CULTIVO POR FILTRADO A VALORES DE PH 9,5 (DIVIDIDO POR) 13,0; INCLUIDA EN UNA MASA SOLIDA, ES PRECIPITADA DE LA SUSTANCIA FILTRADA OBTENIDA, A UN PH 2,5 (DIVIDIDO POR) 4,0, EN PRESENCIA DE UN FILTRO INERTE, ANTIOXIDANTE Y NO MISCIBLE CON UN DISOLVENTE ORGANICO EN AGUA. SE EXTRAE Y SE LACTONIZA EN UN MEDIO DE UN DISOLVENTE ORGANICO QUE CONTIENE CLORO. ESTE ULTIMO SE CONCENTRA Y EL RESIDUO SE DISUELVE EN UNA MEZCLA DE DISOLVENTES CON DISTINTA POLARIDAD. DESPUES DE ENFRIAR A TEMPERATURAS ENTRE 10 (GRADOS) C Y -30 (GRADOS) C, LA LOVASTATINA SE CRISTALIZA, SE SECA Y SE VUELVE A CRISTALIZAR VARIAS VECES.
Patent CY-1108710-T1 (CY)
Title: Παραγωγα της καρβαματης του 2η- η του 3η-βενζο[ε] ινδαζολ-1-υλιου, η παρασκευη τους και η θεραπευτικη εφαρμογη τους
Inventor: DUBOIS LAURENT
IPC: A61K31/416
Filed: 2009-01-14
Abstract: Η εφεύρεση αφορά στις ενώσεις με το γενικό τύπο (I): όπου το W αντιπροσωπεύει ένα άτομο οξυγόνου ή θείου, τα Χ1, Χ2, Χ3 και Χ4 αντιπροσωπεύουν το καθένα, ανεξάρτητα το ένα από το άλλο, ένα άτομο υδρογόνου ή αλογόνου ή μία ομάδα κυανίου, C1-C6- αλκυλίου, C1-C6-φθοροαλκυλίου, C1-C6-αλκοξυλίου, C1-C6-φθορο- αλκοξυλίου, το Υ βρίσκεται στη θέση (Ν2) ή (Ν3), όταν το Υ βρίσκεται στη θέση (Ν2), το Υ αντιπροσωπεύει μία ομάδα C1-C6-αλκυλίου, C1-C6-φθοροαλκυλίου, αρυλίου ή ετεροαρυλίου, όταν το Υ βρίσκεται στη θέση (Ν3), το Υ αντιπροσωπεύει μία ομάδα αρυλίου ή ετεροαρυλίου, οι ομάδες αρυλίου ή ετεροαρυλίου είναι ενδεχομένως υποκατεστημένες με ένα ή περισσότερα άτομα ή με μία ή περισσότερες ομάδες που επιλέγονται από τα άτομα αλογόνου, τις ομάδες C1-C6-αλκυλίου, C1-C6- αλκοξυλίου, C1-C6-αλκυλο-θείου, C1-C6-αλκυλο-S(O)-, C1-C6-αλκυλο- S(O)2-, C1-C6-φθοροαλκυλίου, ο δεσμός στη θέση C4 ή C5 είναι διπλός ή απλός, τα R1 και R2 αντιπροσωπεύουν το καθένα, ανεξάρτητα το ένα από το άλλο, μία ομάδα αρυλίου, βενζυλίου ή C1-C6-αλκυλίου, ή ακόμη τα R1 και R2 σχηματίζουν, με το άτομο αζώτου που τα φέρει, έναν ετεροκυκλικό δακτύλιο ενδεχομένως υποκατεστημένο με μία ή περισσότερες ομάδες C1-C6-αλκυλίου ή βενζυλίου, σε κατάσταση βάσης ή ενός άλατος προσθήκης ενός οξέος, καθώς και στην κατάσταση ενός υδρίτη ή ενός επιδιαλυτωμένου χημικού σωματιδίου. Μέθοδος παρασκευής και θεραπευτική εφαρμογή.
Patent CY-1109054-T1 (CY)
Title: Ρρυ αγωνιστες και χρησεις αυτων
Inventor: FINN RORY FRANCIS
IPC: A61K47/48
Filed: 2009-05-12
Abstract: Η εφεύρεση παρέχει PYY3-36 παραλλαγές και πολυαιθυλενογλυκολιωμένα παράγωγα αυτών και συνθέσεις και μεθόδους χρήσιμες στην θεραπεία καταστάσεων που ρυθμίζονται από έναν αγωνιστή ΝΡΥ Υ2 υποδοχέα.
Patent CY-1109504-T1 (CY)
Title: Αγωνιστες υποδοχεα γουανυλικης κυκλασης για την θεραπεια φλεγμονης ιστου και καρκινογενεσης
Inventor: SHAILUBHAI KUNWAR
IPC: C07K7/64
Filed: 2009-10-15
Abstract: Αποκαλύπτεται μέθοδος θεραπείας φλεγμαίνοντος, προ-καρκινώδους ή καρκινώδους ιστού ή πολυπόδων σε ένα υποκείμενο θηλαστικό. Η θεραπεία περιλαμβάνει χορήγηση μίας σύνθεσης από τουλάχιστον ένα πεπτίδιο αγωνιστή ενός υποδοχέα γουανυλικής κυκλάσης ή/και άλλα μικρά μόρια που αυξάνουν ενδοκυτταρική παραγωγή του cGMP. Το τουλάχιστον ένα πεπτίδιο αγωνιστής ενός υποδοχέα γουανυλικής κυκλάσης μπορεί να χορηγηθεί είτε μόνο είτε σε συνδυασμό με έναν αναστολέα της εξαρτώμενης από cGMP φωσφοδιεστεράσης. Ο αναστολέας μπορεί να είναι ένα μικρό μόριο, πεπτίδιο, πρωτεΐνη ή άλλη ένωση που αναστέλλει την αποικοδόμηση του cGMP. Χωρίς να απαιτεί έναν συγκεκριμένο μηχανισμό δράσης, αυτή η θεραπεία μπορεί να αποκαταστήσει μία υγιή ισορροπία μεταξύ πολλαπλασιασμού και απόπτωσης στον πληθυσμό επιθηλιακών κυττάρων του υποκειμένου και επίσης να καταστείλει την καρκινογένεση. Έτσι, η μέθοδος μπορεί να χρησιμοποιηθεί για να θεραπεύσει μεταξύ άλλων, φλεγμονή, συμπεριλαμβανομένων γαστρεντερικών φλεγμονωδών διαταραχών, γενικής φλεγμονής οργάνου και άσθμα και καρκινογένεση του πνεύμονα, γαστρεντερικής οδού, κύστης, όρχεων, προστάτη και παγκρέατος ή πολύποδες.
Patent CY-1112402-T1 (CY)
Inventor: AICHER THOMAS DANIEL
IPC: C07D401/04
Filed: 2012-02-24
Abstract: The present invention provides compounds of formula I:   
pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.
Patent CY-1113708-T1 (CY)
Title: Αντισωματα υψηλης συγγενειας στον υποδοχεα της ανθρωπινης il-6
Inventor: STEVENS SEAN
IPC: A61P29/00
Filed: 2013-02-21
Abstract: Αντίσωμα ή θραύσμα του δέσμευσης αντιγόνων, που δεσμεύει τον υποδοχέα της ανθρώπινης IL-6 (hlL-6R) με μια KD 500 pΜ ή μικρότερη, όπως μετριέται με συντονισμό επιφανειακών πλασμονίων. Σε προτιμώμενες ενσωματώσεις το αντίσωμα περιλαμβάνει, μεταβλητή περιοχή ελαφριάς αλυσίδας (LCVR) η οποία περιλαμβάνει τις SEQ ID NO: 13, 15 και 17 ως αντίστοιχα CDR1, CDR2 και CDR3 ελαφριάς αλυσίδας, και μεταβλητή περιοχή βαριάς αλυσίδας (HCVR) η οποία περιλαμβάνει τις SEQ ID NO: 5, 7 και 9 ως αντίστοιχα CDR1, CDR2 και CDR3 βαριάς αλυσίδας.
Patent CY-1120147-T1 (CY)
Inventor: WEBER DAVID
IPC: A61K9/22
Filed: 2018-02-28
Abstract: The invention provides biodegradable implants sized for implantation in an ocular region and methods for treating medical conditions of the eye. The implants are formed from a mixture of hydrophilic end and hydrophobic end PLGA, and deliver active agents into an ocular region without a high burst release.