baber/WOPTO huggingface dataset:
Patent RU-2726825-C2 (RU)
Inventor: FORNARA MARGARET SERZHEVNA
IPC: C12Q1/683
Filed: 2018-12-07
Granted: 2020-07-15
Abstract: Изобретение относится к области молекулярной генетики и предназначено для определения полиморфизма С→Т в позиции 1958 (R1958W) гена DMD, обуславливающего наличие стресс-синдрома у свиней. Проводят амплификацию фрагмента гена, содержащего мутацию, с использованием двух праймеров с последующим гидролизом продуктов ПЦР эндонуклеазой Aci I. Идентификация генотипов животных осуществляется по результатам электрофореза продуктов ПЦР-ПДРФ в агарозном геле. Фрагмент длиной 202 п.о. специфичен для нормального аллеля (нуклеотид С). Фрагмент длиной 234 п.о. соответствует мутантному аллелю (нуклеотид Т). Изобретение обеспечивает создание дешевого способа идентификации полиморфизма в гене DMD, обуславливающего наличие стресс-синдрома у свиней. 2 ил., 1 пр.
Patent RU-2765719-C2 (RU)
Title: Method for producing polymorph form of 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-n-cyclopropyl-4-methylbenzamide
Inventor: SULEIMAN OSAMA
IPC: C07D231/38
Filed: 2017-07-13
Granted: 2022-02-02
Abstract: FIELD: organic chemistry.SUBSTANCE: group of inventions relates to organic chemistry and represents methods for producing a form B of 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-N-cyclopropyl-4-methylbenzamide having a powder X-ray diffraction pattern measured using Cu Kα radiation with peaks at 2θ approximately = 9.6, 10.1, 11.4, 13.1, 13.9, 14.8, 15.4, 15.8, 17.0, 17.4, 18.5, 18.8, 19.7, 19.9, 20.5, 21.0, 21.9, 22.9, 23.6, 24.6 and 25.7°. Methods are carried out by dissolving 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-N-cyclopropyl-4-methylbenzamide at a temperature of at least 75°C in a solvent or a mixture of solvents selected from a group consisting of C1-6alcohols or mixtures thereof and containing less than approximately 5% by weight of water relatively to initial substance. The resulting solution is cooled at a temperature not exceeding 40°C. Then, isolated crystals are heated at a temperature from 75 to 210°C for more than 1 min, obtaining the form B of 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-N-cyclopropyl-4-methylbenzamide. An alternative method for the production includes: dissolution of 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-N-cyclopropyl-4-methylbenzamide at a temperature of 105°C in an anhydrous solvent or a mixture of anhydrous solvents selected from a group consisting of C1-6alcohols or mixtures thereof; optional filtration of the resulting solution to remove particles with a maximum diameter of more than 100 mcm; cooling of the solution to 85°C; introduction of a seed in a solution of crystals of the form B of 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-N-cyclopropyl-4-methylbenzamide; optional additional cooling of the solution; optional addition of a seed to the solution of crystals of the form B of 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-N-cyclopropyl-4-methylbenzamide; cooling of the solution to less than 70°C and isolation of crystals of the form B of 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-N-cyclopropyl-4-methylbenzamide.EFFECT: methods make it possible to obtain a crystalline modification of 3-[5-amino-4-(3-cyanobenzoyl)pyrazole-1-yl]-N-cyclopropyl-4-methylbenzamide, which has a combination of several properties, namely improved hygroscopicity, thermodynamic stability and solubility.32 cl, 9 dwg, 3 tbl, 3 ex
Patent RU-2756497-C2 (RU)
Title: Method of separating multicomponent mixtures of low-boiling and homogeneous-soluble liquids and a distillation column for its implementation
Inventor: Skripilev Mikhail Yurevich
IPC: B01D3/32
Filed: 2019-02-15
Granted: 2021-09-30
Abstract: FIELD: separation of substances into different fractions by distillation.SUBSTANCE: distillatory beer column comprising a heater, a distillation cube, a column body, a refluxer, a steam line and a condenser, it differs from known designs in that there is a refluxer tube inside the column housing, the lower part of which is lowered into the water lock device.EFFECT: technical result is reduction of power inputs and time of obtaining clean fraction from mixture.2 cl, 1 dwg, 2 tbl
Patent RU-2738224-C2 (RU)
Inventor: DUROV DMITRIJ SERGEEVICH
IPC: F41F3/06
Filed: 2019-03-22
Granted: 2020-12-09
Abstract: FIELD: aviation. 
     SUBSTANCE: invention relates to design of aircraft missile systems. Multipurpose missile aircraft system comprises optional and remotely piloted two-body helicopters, including variable-sweep oblique wing (VSOW) and on its arms two single-blade bearing rotors (SBBR), mounted on underwing fuselages-nacelles (UFN). UFN are equipped with combined engines, having free power turbines, driving SBBR and remote fans, creating at the vertical and short take-off/landing (VTL and STL) propulsive and lifting tie-rod with operating/autorotating SBBR or fixed SBBR along the UFN axis during horizontal flight in configuration of jet rotorcraft/gyroplane or aircraft. Aviation guided missiles are arranged in bomb compartments. SBBR have units for fixation of blades and counterweights in position backward and forward on flight and over VSOW in field-charging configuration of aircraft-helicopter for its transportation and maintenance in hangar of aircraft carrier. 
     EFFECT: higher probability of destruction of surface, underwater targets located at long range, and possibility of its attack after prolonged flight in hovering mode. 
     5 cl, 1 dwg, 1 tbl
Patent RU-2741591-C2 (RU)
Inventor: LEME MARK-ANDRE
IPC: A47G9/02
Filed: 2017-10-06
Granted: 2021-01-27
Abstract: FIELD: pneumatic; bed-clothes. 
     SUBSTANCE: bedding system, method and kit for automatic processing and ventilation of available duvet are described. System comprises inflatable pad, made with possibility of insertion and attachment to quilt with feather duvet, wherein the inflatable liner comprises a network of pneumatic chambers forming a plurality of openings passing through the lining, which allow air to circulate through the lining; and an air pump, functionally connected to the inflatable lining for injecting air into the pneumatic chambers network, so that when used inflatable liner inflates, to enable stretching the duvet and the corresponding duvet cover into the initial position after each bed usage. System may also contain a subnet for supplying warm or cold air in order to control temperature of bed linen. 
     EFFECT: in contrast to traditional systems, proposed invention is a lightweight and easily adapted to commercially available beds system. 
     20 cl, 15 dwg
Patent RU-2769132-C2 (RU)
Inventor: HAO HUAIXIANG
IPC: A61P35/00
Filed: 2018-01-08
Granted: 2022-03-28
Abstract: FIELD: pharmaceutics. 
     SUBSTANCE: group of inventions relates to a pharmaceutical combination containing ALK inhibitor in a free form or its pharmaceutically acceptable salt and SHP2 inhibitor in a free form or its pharmaceutically acceptable salt, and to its use. A pharmaceutical combination is proposed for the treatment of ALK-positive cancer, including (i) ALK inhibitor or its pharmaceutically acceptable salt, where ALK inhibitor is ceritinib, and (ii) SHP2 inhibitor and, optionally, a pharmaceutically acceptable carrier for simultaneous or subsequent injection. The combination is suitable for the treatment of cancer with rearranged ALK. Joint targeting on ALK and SHP2 amplifies an antiproliferative effect of ALK inhibitor, even in case of cancer resistant to ALK inhibitor. 
     EFFECT: inventions provide the reduction in RAS-GTP loading cell potential and inhibit the restoration of phospho-ERK, which can overcome non-targeted resistance in cancer with rearranged ALK, such as NSCLC. 
     15 cl, 4 dwg, 3 tbl, 5 ex
Patent RU-2764885-C2 (RU)
Title: Grinding of metal grains using direct oscillation energy transmission in production of cast metal workpieces
Inventor: GILL KEVIN SKOTT
IPC: B22D11/053
Filed: 2018-03-07
Granted: 2022-01-24
Abstract: FIELD: casting. 
     SUBSTANCE: invention relates to the production of cast metal workpieces with an adjustable grain size. A molten metal conveyor contains a receiving plate that is in contact with molten metal during the transportation of molten metal. The receiving plate runs from an input, at which molten metal enters the receiving plate, to an output, at which molten metal leaves the receiving plate. The molten metal conveyor contains at least one oscillation energy source, which transmits oscillation energy directly to the receiving plate in contact with molten metal.  
     EFFECT: invention provides the maximization of the speed of casting into ingots, an increase in the resistance to the formation of hot cracks, the minimization of the separation into elements, an improvement of mechanical properties, in particular plasticity, an improvement of final characteristics of processed products and an improvement of characteristics related to filling the mold, as well as a reduction in the porosity of casting alloys. 
     21 cl, 16 dwg
Patent RU-2759870-C2 (RU)
Inventor: SOLBERG JAN FREDRIK
IPC: A61N5/06
Filed: 2018-03-06
Granted: 2021-11-18
Abstract: Группа изобретений относится к медицинской технике. Оптическое терапевтическое устройство содержит переднюю часть корпуса, источник света, предоставленный в указанной передней части корпуса, сферическую просвечивающую кварцевую линзу, предоставленную перед указанным источником света, ободок, предоставленный на указанной передней части корпуса и выполненный с возможностью удерживать указанную сферическую просвечивающую кварцевую линзу так, что часть кварцевой линзы выступает за кромку ободка. Также описаны способ использования устройства для применения стимуляции светом к акупунктурным точкам организма человека или животного и способ получения устройства. 3 н. и 7 з.п. ф-лы, 7 ил.
Patent RU-2766234-C2 (RU)
Title: New bispecific antigen-binding molecules with capability of specifically binding to cd40 and fap
Inventor: BRUENKER PETER
IPC: C07K16/28
Filed: 2018-04-03
Granted: 2022-02-10
Abstract: FIELD: biotechnology. 
     SUBSTANCE: invention relates to biotechnology and is new bispecific antigen-binding molecules containing (a) at least one antigen-binding domain having the capability of specific binding to CD40, and (b) at least one antigen-binding domain having the capability of specific binding to fibroblast-activating protein (FAP), and methods for obtaining the specified molecules, and methods for their application.  
     EFFECT: invention makes it possible to expand the spectrum of bispecific antibodies with a given activity. 
     23 cl, 25 dwg, 31 tbl, 5 ex
Patent RU-2762414-C2 (RU)
Title: Device for winding flexible pipe
Inventor: KANDIN PATRIS
IPC: B65H75/00
Filed: 2018-07-04
Granted: 2021-12-21
Abstract: FIELD: winding devices. 
     SUBSTANCE: invention relates to a device for winding a flexible pipe that can also be used for winding ropes, electrical wires and cables. The device for winding contains two same plates pressed against each other with a “jack” placement and attached to each other along their corresponding axes of the axial symmetry with the possibility of pivot that together form a pivot axis PIV. One of the specified plates has on its left edge an open up recess formed by the first circular arc, the beginning of which is located at a connection point placed on the right edge of the recess on a longitudinal axis of the specified plate. A diameter of the first circular arc lies on the longitudinal axis, wherein the first circular arc has a central angle α of no less than 180°. 
     EFFECT: device provides for the simplification of winding long-length materials. 
     7 cl, 3 dwg
Patent RU-2761348-C2 (RU)
Title: System for purification of water areas
Inventor: FAJOLLE PER-EDUARD
IPC: E02B15/10
Filed: 2018-06-21
Granted: 2021-12-07
Abstract: FIELD: treatment of water. 
     SUBSTANCE: invention is intended for purification of water areas. The system for purification of water areas comprises at least one container (100) configured to be filled with water polluted with garbage, in particular, with microparticles of plastic, and simultaneously allowing for evaporation of water, means (300) configured to pump a controlled volume of water into the container, and means (410) configured to collect solid deposition (210) remaining in the container (100) after evaporation of the water. The means of collecting solid deposition comprise a film (410) located on the inner surface of the container for filling with contaminated water, wherein said film is configured to be rolled or folded. 
     EFFECT: effective purification of water areas from pollution. 
     20 cl, 11 dwg
Patent UA-61999-C2 (UA)
Title: Contact system of a switch
IPC: H01H31/00
Filed: 2000-12-19
Abstract: According to the present invention, a contact system is proposed for an electric switch that is designed for installation at transformer and distribution substations of power-supply systems. The contact system contains two main contacts, one of which is designed as one or several lamellas, a spring mechanism for producing pressure on the main contacts, and additional contacts with springs for producing pressure on these contacts. Each of the additional contacts is designed as a plate made from material with shape memory effect. At the initial state, when the additional contacts are closed, the additional contact plate is bend relative to the plane that passes through the contact point of the contacts and is perpendicular to the direction of the force produced by the contact spring. The additional contacts made from material with shape memory effect provide the possibility to increase the speed of opening the contacts when the switch operates at short circuit in the electric circuit protected by the switch. As a result, the switching capacity of the switch is increased. The short-circuit current passing through the additional contacts of the switch, induces intensive heat emission causing the change of the shape of the additional contact plates (within a time interval of 0.02 ... 0.04 s) that stimulates accelerated opening of the contacts.
Patent UA-47749-C2 (UA)
Title: Method of film cooling and appliance for its implementation
Inventor: KHALATOV ARTEM ARTEMOVYCH
IPC: F01D5/00
Filed: 2001-09-03
Abstract: A cooling by a film method includes blowing of the cooling air onto a hot blade surface. By delivering a hot air to the blade surface across the main gas flow at least one row of the pulsed vortexes is formed. A device for the cooling by a film method implementation contains a gas turbine blade with the grooves, in which on the rarefaction and pressure surface along the blade height the pits are disposed, and in every of which at the upper by the flow direction half the holes are made for introducing the cooling air.
Patent UA-81124-C2 (UA)
Title: Composition for heart disease treatment based on extracts of radix salviae and panax notogingseng roots, method to prepare and uses thereof
IPC: A61P25/00
Filed: 2003-07-31
Abstract: The invention provides compositions comprising extracts of Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneol. This invention also provides a method of preparation of the said.
Patent UA-77604-C2 (UA)
Title: Method for producing coke cakes
Inventor: MAIMUR BORYS MYKYTOVYCH
IPC: C22B1/24
Filed: 2005-08-02
Abstract: An invention relates to by-product coking production and can be used in making cakes of coke breeze. A method comprises mixing polydisperse coke breeze with size to 6 mm with binding material, briquetting mixture, thermal treatment and cooling cakes. In mixing there is added to mixture coke dust entrapped in systems of gas cleaning of by-product coke plant with size to 0.25 mm at an amount of 15-50 % of mass of coke composition mixture. Technical result: simplification of the process of production due to elimination of operations for following and forming fraction composition of coke composition mixture.
Patent UA-87479-C2 (UA)
Title: Farm assembly unit
Inventor: SHEVCHENKO VIKTOR HRYHOROVYCH
IPC: A01B35/00
Filed: 2006-06-09
Abstract: A farm unit comprises two tractors connected to a shuttle plough arranged between the tractors by ropes of pulling winches. The ropes are fixed to opposite trailing hooks on a frame of the shuttle plough. The body of the shuttle plough is shaped as a parallelogram. On trailers, connected to the tractors, electric cranes, electric power generators, complexes for protecting the ropes of the pulling winches from soil friction are arranged. The technical result is in lowering fuel consumption for carrying out tillage, reducing expenses for repair, favourable conditions of maintenance support of the tractors.
Patent UA-84177-C2 (UA)
Title: gaseous-hydrate method of concentration of liquid biological preparations
Inventor: BOHACHUK YURII BORYSOVYCH
IPC: B01D9/00
Filed: 2006-06-19
Abstract: The invention relates to the gaseous-hydrate method of the concentration of liquid biological preparations. Hydrate formation is conducted in the same volume during mixing of solution at a temperature of 7-10 °C and addition of gaseous-hydrate agent under pressure of 3-5 atm. during 3-6 min. Formed gaseous-hydrates and concentrated solution of biological preparation are divided into layers. The end product - concentrated solution of biological preparation – is evacuated, formed gaseous-hydrates are melted with obtaining of additional end product - weak concentrated solution of biological preparation. The gaseous-hydrate agent, which was isolated during melting, is regenerated for repeated use. As gaseous-hydrate agent Freon R22 is used.
Patent UA-85724-C2 (UA)
Title: Meter of electric energy
Inventor: CHERMISIN MYKOLA MYKHAILOVYCH
IPC: G01R21/06
Filed: 2007-01-23
Abstract: The invention relates to area of measuring devices, in particular to meters of electric energy. To meter of electric energy that has contact shoe, current indicators, voltage indicators, power supply block, micro-controller, galvanic decoupling, elements of interface, liquid-crystalline indicator and permanent memory temperature indicator is included, and analog-digital transformer. Technical result of the invention is in increase of functional abilities of meter due to additional account of losses of electric energy in wires through account of effect of temperature of environment.
Patent UA-94473-C2 (UA)
Title: Elastic clutch with coil elastic element
Inventor: PROTSENKO VLADYSLAV OLEKSANDROVYCH
IPC: F16D3/52
Filed: 2009-02-16
Abstract: The invention relates to machine-building, in particular to clutches, and can be used in drives of different machines. An elastic clutch with coil-like elastic element consists of two half-clutches that are connected by elastic element. According to the invention the elastic element is a cable installed in coil-like way at periphery of half-clutches at outer cylindrical surfaces of those, it is rigidly fixed in half-clutches and can be deformed. The cable can be fixed in axial slots of half-clutches with rings that are installed to outer cylindrical sections of half-clutches. The cable can be fixed on outer cylindrical sections of half-clutches by holders that are pressed with screws installed to radial threaded openings of half-clutches. The invention provides increase of damping and compensation ability, service life and reparability.
Patent UA-101621-C2 (UA)
Title: Device and method for ice cubes production
Inventor: SCHOONEN WILHELMUS FRANCISKUS
IPC: F25C1/00
Filed: 2008-07-01
Abstract: Device and method for making ice cubes, comprising a supplying device for supplying a liquid substance to at least one elongated mould (1) and a refrigerating device for freezing said liquid substance, which at least one mould defines a space for an ice column which is at least substantially closed at least while said liquid substance is being refrigerated. The at least one mould comprises two mould halves (Ia, Ib) which are movable relative to each other, so that the mould halves can be moved apart once the ice column has been formed. Method for making ice cubes, comprising the steps of a) supplying a liquid substance to a mould, b) freezing the liquid substance in the mould, and c) removing the ice cubes thus formed from the mould, wherein the liquid substance is supplied in step a) to a mould comprising an at least substantially closed space.
Patent UA-99494-C2 (UA)
Title: Pyridazinone derivatives, herbicidal compositions and method for controlling growth of undesired vegetation
Inventor: STEVENSON THOMAS MARTIN
IPC: C07D409/14
Filed: 2008-12-19
Abstract: Disclosed are compounds of Formula (1), N-oxides, and salts thereof, wherein Wis O or S, and R, R, R, G and J are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention., I
Patent UA-100431-C2 (UA)
Inventor: POLITANSKYI LEONID FRANYTSOVYCH
IPC: G10H1/00
Filed: 2011-02-03
Abstract: Клавіатурний амплітудний модулятор належить до радіотехніки і може бути використаний у різноманітних електромузичних та електроакустичних пристроях. Клавіатурний амплітудний модулятор містить вхід модулятора, транзистор, два резистори, конденсатор, контакт, резистивний елемент, джерело постійної напруги та вихід модулятора. Резистивний елемент, електричний опір якого залежить від сили короткотривалої механічної взаємодії в поєднанні з електричним контактуванням першого виводу резистивного елемента з контактом, причому електричний опір резистивного елемента відновлюється до вихідної величини після закінчення механічної взаємодії, а другий вивід резистивного елемента з'єднаний з другим виводом джерела постійної напруги. Технічним результатом є реалізація залежності величини вихідного сигналу клавіатурного амплітудного модулятора від сили короткотривалої механічної взаємодії в поєднанні з електричним контактуванням резистивного елемента з контактом.
Patent UA-102553-C2 (UA)
Title: Cleaner of root heads from tops residues
Inventor: KALETNIK HRYHORII MYKOLAIOVYCH
IPC: A01D33/02
Filed: 2011-03-10
Abstract: The applied cleaner of root heads from tops residues has an elastic cleaning element shaped as a truncated cone, inside of which a conic spiral spring, feeling the internal shape of the cone, is arranged. The front end of the spring is fixed on the shaft, and the rear one is connected with the elastic cone with the aid of rigid plates arranged on the generatrix base of the cone.
Patent UA-107932-C2 (UA)
Inventor: WITSCHEL MATTIAS
IPC: C07D413/04
Filed: 2010-11-06
Abstract: Даний винахід належить до бензоксазинонів загальної формули І, Iде перемінні визначені відповідно до опису, до способів та інтермедіатів для приготування бензоксазинонів формули І, композицій, що містять їх, та до їх застосування як гербіцидів, тобто для боротьби зі шкідливими рослинами, і також до способу боротьби з небажаною рослинністю, який включає забезпечення можливості гербіцидно активній кількості принаймні одного бензоксазинону формули І діяти на рослини, їх насіння та/або на їх природне середовище.
Patent UA-105107-C2 (UA)
Title: Airtight bag for infusion solutions and special liquid or granular products
IPC: B65D47/36
Filed: 2013-02-13
Abstract: The invention relates to packaging and is used for storage and use of liquid products. It can be used in pharmaceutical, food, chemical and other branches of industry. An airtight bag for infusion solutions and special liquid or granular products comprises sheets for inner pack, sheets for outer pack and heat-sealed seams on the packs. The sheets of the inner pack are smaller than the outer pack, transverse and one longitudinal seams of both packs are common, and the second longitudinal seam of each of the individual packs is separate, a common longitudinal seam has an oval insert, and the space between packs may, if necessary, be filled with special gas or other medium. The invention can simplify the design of bag, expand its scope of application and implement special storage conditions of the product placed therein.