baber/WOPTO huggingface dataset:
Patent PT-841923-E (PT)
Inventor: TEDFORD CLARK E
IPC: C07D233/64
Filed: 1996-06-06
Abstract: The present invention is directed to 1H-4(5)-substituted imidazole derivates of formula (I), wherein A is (a); (b); or (c) where R1 is lower alkyl or lower alkoxy; R2, R3, R4, R5, R7 and R8 are each independently hydrogen or lower alkyl; R6 is hydrogen, lower alkyl or lower alkoxy and R5 and R6 can be joined to form a 4, 5 or 6 membered ring. The compounds of formula (I) have H3 histamine receptor agonist activity. The pharmaceutically acceptable salts, and individual stereoisomers of compounds of formula (I) above, as well as mixtures thereof, are also contemplated as falling within the scope of the present invention. The present invention also provides pharmaceutical compositions comprising a pharmaceutically acceptable carrier in combination with an effective amount of a compound of formula (I). The present invention also provides a method of treating conditions in which activation of histamine H3 receptors may be of therapeutic importance such as allergy, inflammation, cardio or cerebrovascular disease (i.e., hyper or hypotension, ischemia, stroke, migraine), gastrointestinal disorders (acid secretion, motility) and CNS disorders involving psychiatric disorders (i.e., including anxiety, manic/depressive disorder, schizophrenia, obsessive-compulsive disorders, etc.).
Patent PT-895726-E (PT)
Inventor: LOCATELLI ANTONIO
IPC: A42B3/32
Filed: 1998-06-17
Abstract: A crash helmet with openable chinguard, including a helmet bowl (3), a chinguard (5) which is hinged to the bowl (3), and a means (9) for locking the chinguard, characterized in that it includes a single push button (31) for opening the chinguard with just one hand. <IMAGE>
Patent PT-919164-E (PT)
Inventor: PATRICK MCKANE
IPC: B65D6/00
Filed: 1998-11-30
Abstract: A display system for a freezer cabinet has a number of open topped plastics display bins (1) arranged within the freezer cabinet sub-dividing the freezer cabinet into a number of smaller display compartments each containing products for sale. Each bin (1) comprises an open topped box shaped body (5) having upstanding sidewalls (6, 7, 8, 9) and a base comprising a pair of overlapping floor plates (19, 20) which engage within associated openings (22, 23) in opposed sidewalls (6 and 7, 8 and 9) to secure the floor plates (19, 20) between the sidewalls (6, 7, 8, 9). <IMAGE>
Patent PT-1042305-E (PT)
Inventor: SCOTT WILLIAM J
IPC: C07D263/58
Filed: 1998-12-22
Abstract: This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases and proteolytic enzyme mediated diseases, and pharmaceutical compositions for use in such therapy.
Patent PT-1074268-E (PT)
Title: Preventives or remedies for inflammatory intestinal diseases containing il-6 receptor antagonist antibodies
Inventor: KISHIMOTO TADAMITSU
IPC: A61K38/00
Filed: 1999-03-16
Abstract: A preventive or therapeutic agent for inflammatory bowel disease such as Crohn's disease and ulcerative colitis said agent comprising as an active ingredient an interleukin-6 (IL-6) antagonist such as an antibody directed against IL-6 receptor.
Patent PT-1100540-E (PT)
Inventor: ZAGNOLI GIORGIO
IPC: A61K9/00
Filed: 1999-06-04
Abstract: Sucralfate gel in the dry state in porous granular form having a particle-size distribution of between 100 and 1000 mum, an apparent density of the powder bed of between 0.7 and 0.9 g/ml, a settling index of between 5 and 15%, and a residual humidity of between 5 and 15%, and the corresponding process of preparation, which comprises a treatment with microwaves of a diluted solution of powdered sucralfate gel, with a sucralfate titer of between 20 and 70 wt. %. This solid product may be advantageously used in the preparation of solid pharmaceutical compositions that contain it as single active principle, or else as coating of solid compositions that contain, as active principle, a substance that may cause lesions to the gastric mucosa.
Patent PT-1149259-E (PT)
Title: Electrical accessory for vehicles and the like
Inventor: EL-HAJ ALI
IPC: F23Q7/00
Filed: 1999-09-24
Abstract: An electrical power-operated accessory for automobiles and other vehicles, comprises an automatic electrical cigar lighter or power outlet device consisting of a holder structure which includes a socket having electrical contacts, and either an ignitor plug receivable in the socket for use with tobacco products, or else a power outlet plug to provide a source of power for operating other equipment. The ignitor plug has an electrical heating coil, and the socket has a base-mounted automatic switch to control the operating current. The socket also has safety overload protection in the form of a PTC wafer which functions to prevent overcurrent conditions. A glow ring on the holder or socket is illuminated concurrently with energization of the heating coil or the power outlet, or else separately controlled from an outside source.
Patent PT-1141636-E (PT)
Inventor: BRIDENNE PIERRE
IPC: F24F13/02
Filed: 1999-12-16
Abstract: The invention concerns a soft material sheath (10) for close protection of products arranged on a conveyor or a work top, sensitive to contamination by the environment, by diffusing a sterilized air stream, in particular along a direction substantially perpendicular to said conveyor or work top, said sheath defining a sterilized air supply conduit and having a protrusion (20). The invention is characterised in that in said supply conduit, just after said protrusion with respect to the sterilised air flow direction, is provided a sterilized air diffusing cone (30) oriented in the direction of the sterilized air flow direction and centred on the sheath longitudinal axis.
Patent IE-900053-L (IE)
Title: Fastening system
IPC: F16B43/00
Filed: 1990-01-05
Abstract: In the construction of buildings, multiple superimposed plastic fastening strips (10,12) are employed to affix a building member (8) to a substrate (3). The strips (10,12) are superimposed at least at regions penetrated by mechanical fasteners.
Patent IE-45018-L (IE)
Title: Co-catalyst
IPC: C08F4/20
Filed: 1977-01-28
Abstract: For the preparation of the trichlorides of titanium and vanadium, a metal is vaporised in vacuo and the vapour thus obtained is reacted at low temperature with MCl4, M being Ti or V. The vaporisation of the metal takes place in a vacuum of between 10<-1> and 10<-6> mm Hg, and the reaction of the metallic vapours and MCl4 takes place at temperatures of between -80 and +20 DEG C in the presence of an inert diluent selected from saturated or unsaturated aliphatic hydrocarbons or from halogenated hydrocarbons. The metal to be vaporised is preferably selected from the group comprising Al, Mg, Cr, Mn, Fe, V and Ti. The trichlorides thus obtained and an organometallic aluminium compound are used in catalytic compositions for the polymerisation of alpha-olefins in high yield.
[GB1576431A]
Patent IE-900352-L (IE)
Title: Alkylation catalyst isolation
IPC: B01D17/028
Filed: 1990-01-30
Abstract: In an alkylation process wherein the amount of hydrogen fluoride (HF) acid catalyst required to maintain a desired HT acid/hydrocarbon ratio in a plurality of alkylation reactors (10, 12) is contained in the lower portion of a common settler vessel (14), the improvement comprises: dividing the lower portion of the common settler vessel (14) into a plurality of chambers for containing the desired amount of HF acid catalyst, such that a leak affecting the catalyst handling system for one of the plurality of reactors (10, 12) would only spill the amount of liquid HF acid contained in one of the chambers, and would not affect the liquid HF acid level in a non-leaking chamber.
[EP0384457A1]
Patent IE-890440-L (IE)
Title: Method and plant for pulling-off the hide or skin of animal carcasses
IPC: A22B5/16
Filed: 1989-02-10
Abstract: A method and a plant for pulling-off of the hide or skin of animal carcasses, wherein the plant forms part of a slaughtering line in a slaughterhouse. The carcasses are transported continuously on a transport path (23, 24) suspended from all four legs in an essentially horizontal position and with the longitudinal direction of the carcass in the movement direction of the transport path. In a lead-in area (1) of the path the rearward legs, as viewed in the transport direction, are retained in relation to the movement of the forward legs, and the carcass (9) thereafter is fed under tension with an essentially constant distance between the suspension points of the forward and rearward legs. After preflaying the hide/skin is pulled off by a stripper means, preferably a rotatable drum (91), which, in a stationary operative position below the back of the carcass (16), executes the stripping operation while the carcass (16) passes the stripper means (91).
Patent IE-790607-L (IE)
Title: Contacting different phases
IPC: F26B17/24
Filed: 1979-08-08
Abstract: A device for putting into contact substances existing in at least two different phases, one of which is a gaseous phase introduced into a cylindrical section for helicoidal flow, a divider extending axially through the cylindrical section having openings for passage of the helicoidal streams therethrough to a bicone, an axial passage for introduction of the other phase into the path for engagement by the helicoidal streams for copulverization.
[US4379638A]
Patent IE-870657-L (IE)
Title: Shaped confection product.
IPC: A23G9/20
Filed: 1987-03-13
Abstract: A shaped body of ice cream built up of layers is described. The individual layers (3) of ice cream consist of extruded strands (2) that are laid down in the form of curves, for example an eight, beside and on top of one another. Further, an apparatus for preparing such shaped bodies is described wherein a plurality of nozzles are arranged side by side and with the outlets underneath in a moveably mounted support plate. The supply side of each nozzle is connected via a supply line with a distributor head and the support plate is moved in curves by means of a mechanism. A moveable substrate for the extrudate, for example a conveyor belt or a tray, is arranged underneath the nozzles.
Patent IE-890897-L (IE)
Title: Elastic pliable article
IPC: A61F13/15
Filed: 1989-03-22
Abstract: The pliable portion of the article (80) has a first end portion (1) and a second end portion located at opposite ends of the encircling portion of the article. The first end portion (1) includes an elasticized fastening system (120) having at least one segment (15) which is capable of being elastically shirred along at least a portion of its length. The shirrable portion of the segment (15) comprises an elastomeric member which, prior to the securement of the first and second end portions of the article to one another, is maintained in a prestretched and tensioned condition in the desired direction of shirring. The opposed ends of the shirrable segment in the article (80) are interconnected to one another through the prestretched and tensioned elastomeric member. The prestretched and tensioned elastomeric member is maintained in tension by securing it in fixed relation to at least one rigidifying member (28) to form a composite structure which is strong enough to resist collapse in a direction parallel to the tensile forces acting upon the prestretched and tensioned elastomeric member. In a particularly preferred embodiment, the rigidifying member (28) has a fixed portion (30) permanently secured to the first end portion (1) of the article (80) and a releasable portion (32) which can be separated from the first end portion of the article. The releasable portion (32) of the rigidifying member (28) preferably includes means for securing it to the second end portion (2) of the article (80), and the act of affixing the releasable portion (32) of the rigidifying member (28) to the second end portion (2) of the article (80) automatically releases the tension in the prestretched elastomeric member. Elasticized fastening systems of the present invention can be produced at high speed from continuous webs and cut into discrete segments which are transferred onto a continuously moving web at predetermined points along its length, all while the elastomeric member is maintained in its prestretched and tensioned condition by the rigidifying member.
Patent IE-820929-L (IE)
Title: Pharmaceutical spiro-hydantoin derivatives
IPC: C07D487/10
Filed: 1982-04-20
Abstract: The invention provides novel non-toxic biodegradable derivatives of the formula: <IMAGE> I wherein Ra is (1-12C)alkyl, phenyl, naphthylmethyl or cinnamyl, the aromatic rings of which optionally bear one or two halogeno substituents, or Ra is benzyl optionally bearing up to 3 substituents independently selected from halogeno, trifluoromethyl, (1-4C)alkyl, (1-4C)alkoxy, nitro, cyano and hydroxy; Rb and Rc are independently selected from hydrogen and non-toxic biodegradable protecting radicals, but are not both hydrogen; and benzene ring A optionally bears one substituent selected from halogeno, (1-4C)alkyl, (1-4C)alkoxy, nitro and hydroxy, or bears two substituents independently selected from halogeno, (1-4C)alkyl and nitro; pharmaceutical compositions thereof; and processes for their manufacture. The amides of formula I in which Rb=Rc=H are potent inhibitors of the enzyme aldose reductase. The derivatives of formula I provided by the invention are of use in vivo in the treatment or prophylaxis of certain complications of diabetes or galactosemia.
[US4386100A]
Patent IE-890984-L (IE)
Title: Alpha cyano -3-pyridylalkyl fungicides
IPC: A01N55/00
Filed: 1989-03-29
Abstract: Fungicidal compounds of formula (II): 
<IMAGE>
 in which:
 R denotes
 - a lower alkyl radical optionally substituted by one or more substituents chosen from halogen atoms, preferably chlorine, fluorine or bromine, a lower alkoxy radical, a radical -Si(CH2)xR1R2R3, x = 0, 1, R1, R2 and R3, which are identical or different, being lower alkyl, lower alkoxy, aryl (especially phenyl) or aralkyl (especially benzyl);
 - an alkenyl, preferably allylic, radical, optionally substituted as when R denotes alkyl or by a C1-C3 alkyl group;
 Y = lower haloalkoxy, preferably containing 1 to 3 carbon atoms, advantageously trifluoromethoxy, lower haloalkyl, preferably containing 1 to 3 carbon atoms, advantageously trifluoromethyl, halogen (preferably chlorine or bromine).
 n = 1, 2, 3, it being possible for Y to be identical or different when n = 2, 3.
Patent FI-831757-L (FI)
Inventor: NOREN PER OLLE
IPC: D21C9/00
Filed: 1983-05-18
Abstract: Use of oxygen, oxygen containing gases or substances giving off oxygen in reduction or inhibition of the dark colouring of pulp or paper in white water systems, especially closed ones, in production of pulp and paper, these substances being added to the white water system in such an amount that aerobic conditions are maintained substantially permanently in at least a part of the white water system, i.e. the redox potential is higher than -100mV.
Patent IE-32446-L (IE)
Title: Glass bending mould
IPC: C04B28/24
Filed: 1968-10-24
Abstract: 1,215,169. Mould for bending glass sheets. LIBBEY-OWENS-FORD CO. 25 Oct., 1968 [2 Nov., 1967], No. 50658/68. Heading ClM. [Also in Division B2] A mould for bending heated glass sheets comprises a shaping element 17 having a metal surface 42 conforming to the contour to which the sheet is to be bent, which element has a covering of fibrous refractory material 43 and a refractory coating 44 over the said covering. The insulating material may be an aluminasilica mat, preferably impregnated with colloidal silica. The coating may be colloidal silica mixed with fused quartz. The surface 42 may be sanded and primed prior to applying the covering 43 by use of adhesive layer 45. The coating 44 may be applied by painting the covering 43 with a slurry of refractory material, and heating to vaporize the liquid vehicle. Successive layers up to a thickness of 1/32 inch may be applied. The mould may comprise a skeleton-type mould element, there being channels 22 for cooling fluid, e.g. air, in the element, which may be used in combination with a male mould part to reshape sheets heated to about their softening point in conventional manner.
[GB1215169A]
Patent IE-43138-L (IE)
Title: Quinolizines
IPC: A61P25/28
Filed: 1976-06-21
Abstract: Pentacyclic derivatives of the general formula  wherein R, R1, R2 and R3 are defined hereinbelow are useful as cerebral protectors and vasodilators. (From US4138489 A) [FR2315277A1]
Patent IE-42603-L (IE)
Title: Vessel with twin hulls.
IPC: B63B35/04
Filed: 1975-06-17
Abstract: 1508066 Catamaran vessels J J STENGER 16 June 1975 [18 June 1974] 25595/75 Heading B7A A catamaran vessel has an opening in the stern with a removably hingedly mounted stinger 9, e.g. for pipe laying, located therein, the stinger having tracks (10) Fig. 5, not shown, for a movable device. The stinger is formed from hollow tubes 14 interconnected by transverse tubes so that it is buoyant, and is located by means of conical end portions (17) Fig. 6, not shown, which locate a transverse cylinder 8 which is rotatable about a horizontal axis. The stinger has rollers (21) below the tracks (10). A stern bridge 6 supports a control cabin 7. The opening can be closed by hatch covers. A hoist 12 can move along the deck of the vessel.
[GB1508066A]
Patent IE-831493-L (IE)
Title: Halogenated anilines
IPC: C07C/
Filed: 1983-06-27
Abstract: Process for the manufacture of an optionally halogenated aniline of the formula: <IMAGE> in which Y=halogen, R=H, alkyl (C1-C4) or alkoxy (C1-C4) and n=0 to 5. Halogenobenzenes of the formula: <IMAGE> in which Y, R and n are as above and X=halogen, are subjected to ammonolysis with aqueous ammonia solution, in the presence of copper and 8-hydroxyquinoline. The process can be used, in particular, for the preparation of 3,5-dichloroaniline.
[US4508922A]
Patent IE-871544-L (IE)
Title: Combatting fungal diseases in plants
IPC: A01N47/38
Filed: 1987-06-11
Abstract: IMPROVEMENTS IN OR RELATING TO FUNGICIDE The invention provides a method of combating fungal diseases in plants with the aid of a) the compound of formula I <IMG> I hereinafter referred to as "Compound A", and b) the compound of formula II <IMG> II and fungicide compositions comprising said compounds.
[CA1329117C]
Patent IE-45569-L (IE)
Title: Serving plate set
IPC: A47G23/06
Filed: 1977-08-23
Abstract: A serving plate set having two similar receptacles which in one form is separated by a sealing member that segregates the receptacle contents, such member also being of a plate-like configuration and which in another form employs the two receptacles to create a closured container.
[CA1084007A]
Patent IE-861770-L (IE)
Title: Multilayer ion test means
IPC: G01N33/52
Filed: 1986-07-01
Abstract: A multilayer test means for determining the presence of an ion in an aqueous test sample, a method for preparing it and a method for using it. The test means comprises a reagent layer containing an ionophore capable of forming a complex with the ion and reporter substance capable of interacting with the complex of ionophore and ion to produce a detectable response, a reflecting layer and optionally an opacifying layer. The multilayer format is particularly suited to whole blood electrolyte determinations and does not require washing or wiping before use. A hematocrit independent whole blood potassium test is provided.
[EP0207392A2]
Patent IE-862171-L (IE)
Title: Adapter for car radio
IPC: H04H20/88
Filed: 1986-08-12
Abstract: A portable stereo cassette tape player is connected to an FM automobile radio through an adapter having an input plug which is inserted into the audio signal output terminal of the tape player and an output plug which is inserted into the cigarette lighter receptacle of the car. The direct voltage from the car battery is filtered and connected to a frequency modulation oscillator stage in which the audio signal from the tape player frequency modulates the oscillator. The weak frequency modulated signal is coupled into the FM car radio through the cigarette lighter receptacle by stray capacitance of the wires connected to the common power source or battery and proximity to the antenna and input stage of the radio. A tuning capacitor tunes the oscillator frequency to an unused location on the dial between local FM radio stations so that the audio signal can be heard on the normal frequency modulation radio band over the radio loud speakers.
[US4712250A]
Patent IE-40447-L (IE)
Title: Azabicycloalkanes
IPC: A61K31/40
Filed: 1974-12-03
Abstract: 1458217 Disubstituted azabicycloalkanes SCIENCE UNION ET CIE SOC FRANCAISE DE RECHERCHE MEDICALE 13 Dec 1974 [14 Dec 1973] 58034/73 Heading C2C Novel compounds of the Formula I in which n is 0, 1 or 2; R is a saturated or unsaturated aliphatic hydrocarbon having up to 5 carbon atoms and X 1 , X 2 , X 3 , X 4 and X 5 which are the same or different, each is hydrogen, halogen, hydroxy, trifluoromethyl, nitro, amino, sulphamoyl or C 1-5 alkyl or alkoxy and acid addition salts thereof may be prepared by condensing a compound II an optionally substituted benzoyl chloride III Alternatively compounds of the Formula I in which at least one of the substituents X 1 to X 5 is amino may be prepared by condensing a compound of the Formula II with an acetylaminobenzoic acid IV in which at least one of X<SP>1</SP> 1 to X<SP>1</SP> 5 is acetylamino and the others have the meaning of X 1 to X 5 with the exception that they cannot be amino, and deacetylating the product. The starting materials I are prepared as disclosed and claimed in divisional Specification 1,458,218. 2 - Methoxy - 5 - sulphamoyl - benzoyl chloride is prepared by reacting o-anisic acid with chlorosulphonic acid to yield 2-methoxy-chloro sulphonyl benzoic acid which on reaction with ammonia yields 2-methoxy-5-sulphamoyl-benzoic acid which is converted to its acid chloride. Pharmaceutical compositions of the compounds I or a physiologically tolerable acid addition salt thereof with the usual excipients show anti-emetic, gastric evacuation stimulating, gastric antisecretory, central nervous system depressing and hypotensive activity when administered orally, parenterally or rectally.
[GB1458217A]
Patent IE-812685-L (IE)
Title: PREPARTION OF 5,6,7,7a-TETRAHYDRO-4H-THIENO (3,2-c)¹PYRIDIN-2-ONE DERIVATIVES
IPC: C07D211/74
Filed: 1981-11-17
Abstract: The present invention provides a process for the preparation of 5,6,7,7a-tetrahydro-4H-pyridin-2-one derivatives of the general formula: <IMAGE> (I) in which R is a hydrogen atom or a phenyl radical optionally substituted by at least one halogen atom, lower alkyl radical, lower alkoxy radical, nitro group, carboxy group, alkoxycarbonyl radical or cyano group; R' is a hydrogen atom or a lower alkyl radical and n is 0, 1, 2, 3 or 4; and of their addition salts with mineral or organic acids, wherein a compound of the general formula: <IMAGE> (II) in which R, R' and n have the same meanings as above and R'' is a hydrogen atom or an alkyl radical containing up to 4 carbon atoms, is treated in an organic solvent with gaseous hydrogen choloride and gaseous hydrogen sulphide. The compounds have platelet anti-aggregant and anti-thrombotic properties.
[US4424356A]
Patent IE-882867-L (IE)
Title: Animal drinking container
IPC: A01K7/02
Filed: 1988-09-22
Abstract: An animal drinking container (1) comprises a main compartment (5) and a secondary compartment communicating through an opening. A receptacle portion (20) for drinking water is formed in the lower portion of the main compartment (5). A ball controlled valve in the secondary compartment maintains the level of water in the receptacle portion (20) above the opening. Access openings (21) in front and rear walls (10) and (11) of the container (1) provide access for an animal's head to the receptacle portion (20) for drinking. Doors (30) connected to the front and rear walls (10) and (11) by hinges (32) close the openings (21). A weight (31) mounted on a support arm (34) extending from each door (30), urges the door (30) closed, but is of weight sufficiently low to permit the door (30) to pivot inwardly under pressure from an animal's head. <IMAGE>
[GB2222929A]