baber/WOPTO huggingface dataset:
Patent MX-2022009904-A (MX)
Title: Fgfr tyrosine kinase inhibitors and anti-pd1 agents for the treatment of urothelial carcinoma.
Inventor: MONGA MANISH
IPC: A61K31/498
Filed: 2021-02-11
Abstract: Disclosed herein are methods of treating urothelial carcinoma. In particular, the disclosed methods include combination therapies for the treatment of urothelial carcinoma comprising administering a fibroblast growth factor receptor (FGFR) inhibitor and an anti- PD1 antibody or antigen binding fragment thereof.
Patent MX-2022012792-A (MX)
Title: Overcoming immune suppression with tgf-î² resistant nk cells.
Inventor: LEE DEAN ANTHONY
IPC: A61K35/17
Filed: 2021-04-30
Abstract: Disclosed are engineered feeder cells comprising soluble or membrane bound TGF-b and methods of their use in the production of NK cells resistant to TGF-b and use of said generated TGF-b resistant NK cells to treat a cancer.
Patent MX-2022013774-A (MX)
Title: Proprotein convertase subtilisin/kexin type 1 (pcsk1) variants and uses thereof.
Inventor: FERREIRA MANUEL ALLEN REVEZ
IPC: C12Q1/6883
Filed: 2021-05-03
Abstract: Methods of treating obesity and methods of identifying susceptibility of an obese subject to treatment with an agonist of the leptin-melanocortin signaling pathway are provided herein.
Patent MX-PA01009533-A (MX)
Title: Fastener closure arrangement for flexible packages.
Inventor: STEVEN C LEE
IPC: B65D33/25
Filed: 2001-09-21
Abstract: A flexible package is provided with a shrouded slider fastener closure. A side seal forming the package is enlarged at its upper end to provide a smooth transition of product dispensed from the package, and to shield the slider during dispensing. The enlarged side seal portion is spaced from the fastener tracks. The fastener tracks are deformed to provide a stop, spaced from the side seals, to limit slider movement. A stop of reduced area, enlarging the package opening, is made possible.
Patent MX-PA01010251-A (MX)
Title: Multiple component bleaching compositions.
Inventor: THORNTHWAITE DAVID WILLIAM
IPC: D06L3/02
Filed: 2000-03-24
Abstract: The invention provides liquid bleaching compositions comprising multiple partial compositions held separately from each other in a multiple compartment container. One partial composition comprises a peroxygen bleach compound, preferably hydrogen peroxide. One partial composition (which may be the same as the one containing the peroxygen compound) comprises an imine or oxaziridine bleach activator compound. One partial composition, which is different from the one containing the bleach activator, comprises an alkaline compound in amount sufficient to raise the pH of the total composition to a value at which the bleach system is effective. The bleach activator compound is preferably a sulfonimine or a quaternary imine salt. The number of partial compositions and of the compartments in the container is preferably 2.
Patent MX-PA02001289-A (MX)
Title: Polyester-staple fibers and method for the production thereof.
Inventor: UDE WERNER
IPC: D01F6/92
Filed: 2000-07-25
Abstract: Polyester staple fibers consisting of a polyester, 0.1 to 2.0 w.- % of an incompatible, melt processable, amorphous polymeric additive with a glass transition temperature of 90 to 170 °C and a melt viscosity/polyester component ratio of 1:1 to 10:1, and 0 to 5.0 weight % of usual additives. The polymeric additives in the staple fibers are present in the form of fibrils with a mean diameter of <= 80 nm. The invention also relates to method for the production of staple fibers, comprising mixing and simultaneously shearing the polyesters and the polymeric additives and optionally the usual additives and spinning at a speed of < 2500 m/min relative to form of spun fibers. Said are bundled together to form cables and stretched in aseparate drawframe to form separate reels of fiber, crimped, dried and cut to form staple fibers.
Patent MX-PA02001504-A (MX)
Title: Ectoparasiticidal aqueous suspension formulations of spinosyns.
Inventor: THOMPSON WILLIAM WEBSTER
IPC: A61K47/10
Filed: 2000-08-02
Abstract: The invention provides a stable ectoparasiticidal aqueous suspension formulation of a spinosyn, comprising the spinosyn, or a physiologically acceptable derivative or salt thereof, milled to an average particle size of 1 to 15 microns, a surfactant in an amount effective to facilitate wetting the milled particles; a dispersant in an amount that forms a spinosyn:dispersant weight ration of from 3:1 to 1:5; and water. It also provides a method of controlling an ectoparasite infestation on a small ruminant or companion animal comprising administering an effective amount of such an aqueous suspension formulation.
Patent MX-PA02001725-A (MX)
Title: Production of maleic anhydride.
Inventor: BHARAT M DOSHI
IPC: C07D307/60
Filed: 2000-08-11
Abstract: Nbutane and molecular oxygen are reacted in a first reactor to form maleic anhydride, the produced maleic anhydride is scrubbed to separate maleic anhydride values, nbutane is added to the scrubber gases and these are reacted in a second reactor to form additional maleic anhydride.
Patent MX-PA02004078-A (MX)
Title: A factory scale process for producing crystalline atorvastatin trihydrate hemi calcium salt.
Inventor: WILLIAM TULLY
IPC: C07D405/06
Filed: 2000-12-18
Abstract: A factory scale process for producing crystalline atorvastatin trihydrate hemi calcium salt includes the addition of extra methyl tert butyl ether to the reaction mixture to supersaturate the crystallisation matrix. A seed slurry is made up in a make up delivery vessel and delivered, under pressure, to the reaction mixture. The process produces crystalline atorvastatin calcium, having structure (I) within a consistent size range on a factory scale.
Patent MX-PA02007479-A (MX)
Title: Collector.
Inventor: CROMPTON TIMOTHY ALLAN
IPC: H01J23/027
Filed: 2001-02-05
Abstract: In a multistage collector used in a linear beam tube such as an IOT or klystron, electrode stages (1, 2 and 3) are separated by ceramic rings (5 and 6) having metallised surfaces (7 and 9) to provide distributed bypass capacitors. This eliminates or reduces leakage or any rf energy from the interior of the collector to the outside.
Patent MX-PA02010035-A (MX)
Title: Method for the production of easily wetted, water soluble, powdered at least alkylated non ionic cellulose ethers.
Inventor: HAMMES ALF
IPC: C08L1/26
Filed: 2001-04-12
Abstract: The invention relates to a method for the production of at least alkylated, non ionic cellulose ethers, whereby at least 10 % of all hydroxy groups contained therein are alkylated and which may flocculate in water, within a temperature range of 45 to 95 C. The invention is characterised in that at least one surfactant in solid, liquid or solution form is added to the cellulose for production of the cellulose ether.
Patent MX-PA02011788-A (MX)
Title: Process for inhibiting polymer formation in a vinyl monomer azeotropic dehydration process.
Inventor: WILLIAM JOSEPH GRIECO
IPC: B01D3/34
Filed: 2002-11-28
Abstract: An improved process is provided herein for the purification of polymerizable organic material, e.g., acrylic acid, by azeotropic distillation.
Patent MX-PA03000359-A (MX)
Title: Dietary lipids for improving skin and coat of pets.
Inventor: COUZY FRANCOIS
IPC: A23K50/40
Filed: 2001-06-18
Abstract: Use of a source of dietary lipids containing anti-microbial fatty acids for the preparation of a food composition intended for improving or maintaining the skin health and/or coat quality in a pet by preventing or regulating the growth of skin pathogens and of microflora responsible for the generation of body surface and coat odors.
Patent MX-PA03001068-A (MX)
Title: Method for secondary oil recovery.
Inventor: LIEN LARRY ALLEN
IPC: B01D69/12
Filed: 2001-08-07
Abstract: A method and a system for treating seawater to facilitate secondary recovery of petroleum from a location below a body of saline water by flooding a permeable stratum with the treated water. The system utilizes a spirally-wound cross flow semipermeable membrane cartridge incorporating a three layer membrane arrangement preferably having nanofiltration characteristics which facilitates treatment of open ocean water by a single pass without any chemical or mechanical pretreatment to result in a liquid stream of desired character that can have greater ionic strength than the input seawater, e.g. at least about 18,000 ppm of chloride ion and less than 50 ppm of sulfate ion. This surprising objective is obtained even at high operating temperatures, e.g. as high as about 70 C, through the combination of the construction of the feed spacer and the nanofiltration character of the three layer membrane arrangement.
Patent MX-PA03001482-A (MX)
Title: Process and apparatus for removing nox from engine exhaust gases.
Inventor: DAVID RAYBONE
IPC: F01N13/02
Filed: 2001-08-15
Abstract: A method and apparatus for removing nitrogen oxides from internal combustion engine exhaust emissions consisting of the operations of contacting the exhaust emissions with a non-thermal plasma (1) and a silver doped alumina catalyst (2) and then an indium-doped zeolite catalyst (3).
Patent MX-PA03002123-A (MX)
Title: Fastener having multiple lobed thread.
Inventor: HEMPFLING DAVID C
IPC: F16B25/00
Filed: 2003-03-11
Abstract: A threaded fastener includes a lead having bosses separated from one another by bases along the thread crest. The lead-in and lead-out profiles of the bosses, and other features of the bosses and bases may differ from one another along the fastener shank. The lead-in and lead out profiles may have linear and non-linear surfaces. The lead-in and lead-out profiles may have cutting edges angled toward the direction of propagation of the bosses. The boss profiles may be selected to reduce insertion torque and to provide excellent resistance to pullout. The fastener may be formed by roll threading via a tool made by a plunge EDM process.
Patent MX-PA03002658-A (MX)
Title: Integrated condenser/separator for fuel cell exhaust gases.
Inventor: MEISSNER ALAN P
IPC: H01M8/04
Filed: 2003-03-27
Abstract: An integrated condenser/separator (10) is provided for condensing and separating a condensate (11) from a cathode exhaust gas flow (12) in a fuel cell system (14). The condenser/separator includes a housing (16) and one or more baffle plates (18, 20) positioned in the housing (16) to divide the interior of the housing (16) into two or more gas flow chambers (24, 26, 28) each containing a stack (32, 34, 36) of heat exchange units (30). A condensate drain (106, 108) is provided in each of the gas flow chambers (24, 26) to drain condensate therefrom. The condenser/separator (10) can be configured into any reasonable and independent number of coolant and gas side passes as maybe required to meet the thermodynamic and pressure drop requirements of each particular application.
Patent MX-PA03003140-A (MX)
Title: A process for the preparation of bis-benzazolyl compounds.
Inventor: ELIU VICTOR PAUL
IPC: C07B61/00
Filed: 2001-10-09
Abstract: The present invention provides a process for the preparation of a compound of the formula wherein Y represents -O-, -S- or -N(R<SUB>2</SUB>)-, R<SUB>2 </SUB>being hydrogen, C<SUB>1</SUB>-C<SUB>10</SUB>alkyl or aralkyl; Z represents a 2,5-furanyl, 2,5-thiophenyl, 4,4'-stilbenyl or a 1,2-ethylenyl residue and R<SUB>1 </SUB>represents hydrogen, halogen, C<SUB>1</SUB>-C<SUB>10</SUB>alkyl, C<SUB>1</SUB>-C<SUB>10</SUB>alkoxyl, cyano, COOM or SO<SUB>3</SUB>M, M being hydrogen or an alkaline or alkaline earth metal, characterized by reacting a compound of the formula with a dicarboxylic acid of the formula <?in-line-formulae description="In-line Formulae" end="lead"?>HOOC-Z-COOH (3) <?in-line-formulae description="In-line Formulae" end="tail"?> or an ester thereof, Y, Z and R<SUB>1 </SUB>being as previously defined, in N-methylpyrrolidone or N,N-dimethylacetamide, in the presence of an acidic catalyst and, optionally, in the presence of a secondary solvent capable of removing water from the reaction mixture, which are useful as optical whitening agents for natural and synthetic materials.
Patent MX-PA03004241-A (MX)
Title: A combination drug.
Inventor: CHANDRASHEKHAR MAINDE
IPC: A61K9/00
Filed: 2001-11-12
Abstract: The invention consists of a stable preparation of a combination drug, comprising of an anti-inflammatory agent and an anti-infective agent. The anti-inflammatory agent in this invention is a corticosteroid, and the anti-infective agent is a derivative of quinolone, amino-glycoside or their pharmaceutically acceptable salts. The combination drug essentially comprises of i) an anti-inflammatory agent which is a corticosteroid, ii) an anti-infective agent selected from the group comprising of derivatives of quinolone, aminoglycoside and their pharmaceutically acceptable salts; iii) a complexation enhancing polymer; iv) a solubiliser exhibiting an inclusion phenomenon, along with pharmaceutically acceptable excipients with a suitable carrier system.
Patent MX-PA03011255-A (MX)
Title: Method of using a simulated skin substrate and method for determining material dryness performance.
Inventor: JASON COHEN
IPC: A61F13/15
Filed: 2003-12-05
Abstract: Methods of using an evaluation apparatus for pre-screening a material for use in an absorbent article are provided. The evaluation apparatus includes a simulated body part having a simulated skin substrate. The material is placed proximate the simulated skin substrate, and a predetermined amount of simulated physiological fluid is insulted into the material at a pre-measured location. After a predetermined time, the simulated skin substrate is removed from the body part and fluid loss measurements are taken.
Patent MX-PA03011435-A (MX)
Title: Water-enhanced production of 1,1,1,3,3-pentachloropropane.
Inventor: LLOYD B BRANAM
IPC: C07B61/00
Filed: 2002-06-12
Abstract: A process is provided by which addition of water is used to enhance the production of any hydrochlorocarbon feedstock through the use of Kharasch chemistry, i.e. the combination of a polychlorinated alkane with an olefin to produce a chlorinated or hydrochlorinated alkane with the use of a transition metal compound in homogeneous solution as catalyst. Preferably, water is added to increase the production of 1,1,1,3,3- pentachloropropane by the reaction of carbon tetrachloride and vinyl chloride in the presence of a catalyst mixture of organo phosphate solvent, iron metal and ferric chloride.
Patent MX-PA04001133-A (MX)
Title: Method of preparing silicas, silicas with specific pore-size and/or particle-size distribution and the use thereof, in particular for reinforcing polymers.
Inventor: REMI VALERO
IPC: H01M50/434
Filed: 2002-08-13
Abstract: The invention relates to a novel method of preparing silicas and to highly-structured silicas having the following characteristics: a specific surface area CTAB (SCTAB) of between 40 and 525 m2/g; a specific surface area BET (SBET) of between 45 and 550 m2/g; an object size distribution width Ld ((d84 - d16)/d50), which is measured by XDC particle size analysis after deagglomeration with ultrasound, of at least 0.91; and a pore-size distribution such that ratio V(d5-d50)/V(d5-d100) is at least 0.66. The invention also relates to the use of said silicas as polymer reinforcing fillers.
Patent MX-PA04002165-A (MX)
Title: Flange of a splice protection sleeve and ring for a flange of a splice protection sleeve.
Inventor: YANNICK SCHREIBER
IPC: H02G15/113
Filed: 2002-08-30
Abstract: This ring comprises a collar and means (2, 3) for putting the collar around a cable without slipping the collar over the cable. The collar comprises a base body (1), the inner and outer circumferential lateral faces (4, 6) of which include a male part (7) and a female part (5), respectively; this ring can be used to advantage in a splice protection sleeve flange.
Patent MX-PA04002665-A (MX)
Title: Antimicrobially-treated fabrics.
Inventor: JAMES W CLARK
IPC: D06M13/463
Filed: 2002-08-06
Abstract: A method for forming an antimicrobially-treated fabric is provided. The method includes forming a solution from a liquid and an antimicrobial agent, such as 3-(trimethoxysilyl)propyloctadecyldimethyl ammonium chloride. In one embodiment, a cellulosic fibrous material is combined with a solution while in the pulper to form a liquid suspension such that the antimicrobial agent becomes substantive to the cellulosic fibrous material. A web is formed from the antimicrobially-treated cellulosic fibrous material such that substantially all of the cellulosic fibrous material present within the web is derived from the antimicrobially-treated cellulosic fibrous material. In one embodiment, the web of antimicrobially-treated fibrous material is also hydraulically entangled with a nonwoven substrate. In some embodiments, when dried, the antimicrobial agent forms a covalent bond with the cellulosic fibrous material.
Patent MX-PA04003498-A (MX)
Title: Package lid, method for manufacturing the same and package sealed with the lid.
Inventor: RISTO SALMINEN
IPC: B65D77/20
Filed: 2002-10-15
Abstract: The invention relates to a lid (1) that can be heat-sealed to the opening of a package (2) and peeled off as the package is opened. In addition, the invention comprises methods for manufacturing such a lid and a package sealed with the lid, and also a sealed package equipped with a lid. The lid (1) consists of a fibrous material layer (6), whichmay be paper or cardboard, a polymer oxygen-barrier layer (7), suitable materials of which are polyethylene terephthalate (PET), ethylene vinyl alcohol copolymer (EVOH) or polyamide (PA), and a polymer heat-seal layer (8). In accordance with the invention, the heat-seal layer (8) combines ethylene methyl acrylate copolymer (EMA), ethylene vinyl acetate copolymer (EVA) and polyamide wax, adherence of the heat-seal layer directly to the oxygen-barrier layer (7) having been allowed without any intermediate binder. During the manufacture of the lid, the oxygen-barrier and heat-seal layers (7, 8) can be applied onto paper or cardboard by coextrusion. The packages equipped with a lid in accordance with the invention comprises boxes, cups or goblets, for instance, into which foodstuffs, such as drinks, nutrients fats or ready-made foods have been packaged.
Patent MX-PA04006268-A (MX)
Title: Ultrasonic method for the production of inorganic/organic hybrid nanocomposite.
Inventor: ZHIKAI WANG
IPC: C09C3/06
Filed: 2002-12-19
Abstract: The present invention provides a method for producing organic/inorganic hybrid nanocomposites by use of ultrasonic agitation. The particles are reacted with an organic coupling agent to modify the surface of said particles to inhibit agglomeration.
Patent MX-PA04007103-A (MX)
Title: Refractrory metal and alloy refining by laser forming and melting.
Inventor: PETER R JEPSON
IPC: B22F3/15
Filed: 2003-01-22
Abstract: A process to chemically refine and consolidate tantalum, niobium and their alloys to a fabricated product of net shape or near-net shape with higher throughput, more consistency, and lower manufacturing costs compared to prior art routes or rejuvenate damaged and deteriorated refractory metal parts. Powder metal is loaded into hoppers to be fed into laser forming/melting equipment. A suitable substrate is loaded into a laser forming/melting chamber onto which the powder will be deposited and consolidated in a point-scan process. As the powder is fed onto successive points of the surface of the substrate in linear traces, the laser is used to heat and partially melt the substrate and completely melt the powder. A combined deposition and melt beam traces the substrate surface repeatedly over a selected area to build up a dense coating of controlled microstructure in multiple layers. A fully dense deposit is built up that becomes the desired shape.
Patent MX-PA04009554-A (MX)
Title: Epitope constructs comprising antigen presenting cell targeting mechanisms.
Inventor: DANIEL A SOLTIS
IPC: A61K9/127
Filed: 2003-04-01
Abstract: The invention relates to products and methods to elicit a targeted immune response. In particular, the invention relates to epitope constructs that comprise antigen presenting cell-targeting mechanisms.
Patent MX-PA04010283-A (MX)
Title: Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification.
Inventor: FRANK GOEHRING
IPC: C07K14/47
Filed: 2003-04-16
Abstract: Provided are methods for the treatment of disorders of the central nervous system (CNS) and the eye. In particular, use of compositions comprising a compound capable of modulating a target gene or gene product is described for the preparation of a pharmaceutical composition for the treatment of disorders of the CNS and/or the eye, wherein the composition is designed to be administered outside the blood-CNS and the blood-retina barriers. Furthermore, methods are provided for identifying and obtaining nucleic acid molecules encoding polypeptides involved in CNS disorders or of the eye, methods for diagnosing said disorders as well as transgenic animal deficient in the expression of target genes identified in accordance with the described method. In addition, methods of identifying and isolating drugs that are particularly useful for the treatment of disorders related to the CNS and/or the eye are disclosed.
Patent MX-PA05001304-A (MX)
Title: Oven liner.
Inventor: BRAY PATRICK L
IPC: H05B6/80
Filed: 2003-08-04
Abstract: A microwave oven liner (11) is an injection moulding having a roof (12), a floor (14), a back (15) and two sides (16). The moulding is of food grade polypropylene, such that the liner can be washed in a commercial dishwasher. The liner is sized to be a sliding fit in a microwave oven. The roof is shorter (17) at the front than the floor to allow air circulation. Further, the roof is apertured, also for air circulation, with a series of small c. 4mm bores (18) registering with the roof aperture (8). A lip (19) is provided across the front of the floor to retain split liquid. The external corners (20) are chamfered to clear the silicone seal (9) for instance. The floor has regularly pitched, 2mm high ridges (21) running front to back. The ridges allow circulation of air beneath a container of food being heated in the oven having the liner.
Patent MX-PA05002801-A (MX)
Title: Method and composition for reducing wear in a cutting head of a tunnel boring machine.
Inventor: ELLENBERGER PETER
IPC: C10M173/02
Filed: 2003-09-02
Abstract: A method of reducing wear in a cutting head of a tunnel boring machine, by means of the addition at the cutting head of a foamed aqueous liquid composition, which comprises a foaming agent and a lubricant, the lubricant being selected from the group consisting of high molecular weight polyethylene oxides and bentonite. Preferred foaming agents are anionic and nonionic surfactants. Wear rates of cutting elements of TBMs boring in hard rock are considerably reduced. A wear-reducing foamable concentrate is also described.
Patent MX-PA05005863-A (MX)
Title: Method and apparatus for injecting fluid into meat products.
Inventor: RAY T TOWNSEND
IPC: A23L13/70
Filed: 2003-10-02
Abstract: A method for injecting fluid into meat products comprises taking a plurality of hollow fluid injection needles (21) having sharpened discharge ends, and connecting the needles to a source of pressurized liquid; penetrating the sharpened ends of the needles into the product and thence withdrawing the same while discharging fluid into the product and vibrating the needles by a vibrator (26), for a period of time while they are within the product to enlarge the size of a penetration hole within the product caused by the penetration of the needles to a size greater than the size of the needles to create at least a partial space around the needles to permit fluid from the needles to migrate into the spaces around the needles. The needles have a roughened outside surface.