baber/WOPTO huggingface dataset:
Patent HU-T77345-A (HU)
Title: Mannopyranosyloxy biphenyl derivatives capable of inhibiting the binding of e-selectin,p-selectin or l-selectin to sialyl-lewis x or sialyl-lewis a and pharmaceutical compositions containing them
Inventor: BECK PAMELA J
IPC: C07H15/20
Filed: 1995-04-28
Abstract: This invention relates to compounds that inhibit the binding of E-selectin or P-selectin to sialyl-Lewis<x> or sialyl-Lewis<a> presented on a cell surface having the general structure (II), wherein X is selected from the group consisting of -CO2R, -(CH2)nO(CH2)mCO2R, -(CH2)nCO2R, -O(CH2)nCO2R, -CONH(CHR2)nCO2R, -(CH2)nSO3H, -(CH2)nPO3D1D2, and -OH; A1 and A2 are independently selected from the group consisting of hydrogen, halogen, lower alkyl, -OR, -(CH2)nNR(CH2)mCO2R, -NRR, -CN, -N3, and -NO2; and A3 is hydrogen, halogen, lower alkyl, -(CH2)pNH2, -(CH2)pNR(CH2)qCO2R, or -(CH2)pNH(CH2)qCH3; where n and m are independently 1 to 6, p and q are independently 0 to 12, R is lower alkyl or hydrogen, R2 is any functional group that can be derived from an available  alpha  or  beta  amino acid, and D1 and D2 are independently hydrogen or methyl, and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof. This invention also relates to methods of inhibiting the binding of E-selectin or P-selectin to sialyl-Lewis<x> or sialyl-Lewis<a> presented on a cell surface using said compounds and to pharmaceutically active compositions comprising compounds that inhibit the binding of E-selectin to sialyl-Lewis<x> and to methods of treatment of septic shock, ARDS, Crohn's disease, chronic inflammatory diseases, such as psoriasis and rheumatoid arthritis, and reperfusion injuries that occur following heart attacks, strokes and organ transplants and to the treatment of cancer.
Patent IL-41809-A (IL)
Title: Trifluoromethyl-salicylanilides and process for preparing them
IPC: C07C235/64
Filed: 1973-03-19
Abstract: Anthelminthically active salicylanilides of the formula IN WHICH X1 and X2 each represent hydrogen, chlorine, methyl or trifluoromethyl, Y1 and Y2 each represent hydrogen, chlorine or the nitrogroup, at least one of the substituents Y1 and Y2 not being hydrogen, and Z stands for -OH, -O-CO-alkyl or -O<->H3N<+>-, are described as well as their preparation by reacting a correspondingly substituted salicylic acid chloride or salicylic acid phenyl ester with an aniline derivative carrying the appropriate substituents or by nitrating a corresponding salicylanilide. The salicylanilides of the above formula are used as active ingredients in pharmaceutical preparations having anthelmintic activity.
Patent IL-44145-A (IL)
Title: Dioxatricyclodecanes and their production
IPC: A61K31/35
Filed: 1974-02-05
Abstract: 1436821 4 - Hydroxy - 2,9 - dioxatricyclo [4,3,1,0<SP>3,7</SP>]decanes KALI-CHEMIE PHARMA GmbH 18 Jan 1974 [8 Feb 1973] 02548/74 Heading C2C Novel compounds I in which R 1 is C 1-4 alkyl, R 2 is OCOR 4 or OCONHR 5 when R 3 is hydrogen and R 3 is OCONHR 5 when R 2 is hydrogen (R 4 is C 1-4 alkyl and R 5 is a C 1-6 alkyl, C 2-6 unsaturated aliphatic, C 3-6 cycloaliphatic or aromatic group) and the 10,11 bond may be hydrogenated are prepared by reducing a compound III in which the 10,11 bond may be hydrogenated preferably with a metal hydride to form a mixture of the corresponding 4α- and 4#- hydroxy compounds and reacting the 4α-OH compound with a carboxylic acid chloride R 4 COCl, a carboxylic anhydride (R 4 CO) 2 O, an isocyanate R 5 NCO, an ester or chloride of a carbamic acid R 5 NH-COR 6 (in which R 6 is chlorine or alkoxy) or with phosgene followed by an amine R 5 NH 2 to form compounds I (R 3 =H): compounds I (R 3 = OCONHR 5 ) are prepared from the corresponding 4#-hydroxy compound by the methods described above. Compounds I have sedative, hyprotic and narcotic properties and may be administered orally or parenterally.
[GB1436821A]
Patent IL-45802-A (IL)
Title: Check valve useful in backflow prevention apparatus
IPC: E03C1/10
Filed: 1974-10-07
Abstract: 1490553 Valves GRISWOLD CONTROLS 25 Oct 1974 [26 Oct 1973] 46301/74 Heading F2V In a check valve a closure member 10 is biased by a spring 17 towards a seat 18 and is provided with spaced guiding flanges 20, 21 which move in barrel 12. The flange 20 projects into the outlet passage 28 to provide a throttle 77 the reduction in pressure in which is communicated via groove 22 and passage(s) 23 to a chamber 24 to assist in opening the valve. Two such check valves may be used in series to form a back flow preventer, Fig. 9, which has the chamber 52 between the check valves vented via line 44 and valve 50 when the pressure differential across the upstream check valve falls to a predetermined value which is sensed by ports 67, 70 and is transmitted via passages 45, 46 to the opposite sides of a diaphragm assembly 54 to actuate the valve 50. In a modification the passage 45 is replaced by an axial passage (75) in the valve stem 61 communicating with the line 44.
[GB1490553A]
Patent IL-57648-A (IL)
Title: 2-substituted-5,9-dimethyl-2'-hydroxy-6,7-benzomorphanes,their preparation and pharmaceutical compositions containing them
IPC: A61K31/445
Filed: 1979-06-25
Abstract: Compounds of the formula   <IMAGE>   wherein R1 is methyl, ethyl or propyl; R2 is hydrogen, methyl or ethyl; and R3 is    <IMAGE> (a) <IMAGE> (b)  or   <IMAGE> (c)  where R4 is hydrogen or methyl, R5 is methyl, ethyl or propyl, and n is 1 or 2, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful as analgesics.
Patent IL-57738-A (IL)
Title: Prostaglandin derivatives of the delta 2,4-11-deoxy-pge series,process for their preparation and pharmaceutical compositions containing them
IPC: C07D319/14
Filed: 1979-07-06
Abstract: The present invention relates to novel prostaglandin derivatives of the formula I    <IMAGE>  I  which are structurally related to the naturally occurring prostaglandins and in which R1 denotes (a) hydrogen or a straight-chain or branched, saturated or unsaturated aliphatic or cycloaliphatic hydrocarbon radical having up to ten carbon atoms or (b) a physiologically acceptable metal or NH4 ion or an ammonium ion which is derived from a primary, secondary or tertiary amine and R2 denotes a straight-chain, aliphatic hydrocarbon radical having up to six carbon atoms and to a process for their manufacture. The compounds of the invention are distinguished in particular by gastric acid secretion-inhibiting and ulcer-protective properties.
Patent IL-62894-A (IL)
Title: Dibenzoxazepine derivatives,process for preparing the same and pharmaceutical compositions comprising the same
IPC: A61K31/55
Filed: 1981-05-18
Abstract: Dibenzoxazepine derivatives of the formula:  <IMAGE>  wherein R1, n, R2 and R3 are as defined in the description, process for preparing the same, pharmaceutical composition containing the same and method of treating diseases in circulatory organs administering the composition to a patient are disclosed. The compounds of the formula have lipid lowering activity, lipid peroxide lowering activity, blood sugar lowering activity and activity to inhibit the aggregation of platelets, and hence are useful as a medicine.
Patent IL-71987-A (IL)
Title: N-(beta-fluoroethyl)nortropine,its preparation and use in preparation of the corresponding 3-alpha-benzilate
IPC: C07D451/06
Filed: 1984-06-01
Abstract: The compound of the formula   <IMAGE>   and acid addition salts thereof. The compounds are useful as intermediates for the preparation of N-( beta -fluoroethyl)-nortropine benzilate.
Patent IL-73803-A (IL)
Title: Recombinant gamma interferons having about 126-143 amino acids, process of preparation and compositions containing them
IPC: A61P35/00
Filed: 1984-12-11
Abstract: The present invention relates to novel, stable recombinant gamma interferons exhibiting in greater or less degree the antiviral and antiproliferative activity in humans and pH 2 labile properties characteristic of native human gamma interferon. The amino acid sequence of such an interferon comprises, from the N terminus, at leastwherein X is a methionine residue or hydrogen and Y is a glutamine residue or, where X is is hydrogen, Y is either a glutamine or a pyroglutamate residue.
Patent IL-85603-A (IL)
Title: Synergistic compositions of interleukin-2 and mismatched double- stranded rna
IPC: A61K38/00
Filed: 1988-03-01
Abstract: The unexpected synergistic interplay between lymphokines and dsRNAs which dramatically reduces the necessary dosages of lymphokines, especially IL-2, and simultaneously widens their therapeutic range in the treatment of various types of cancers, viral disorders or other body conditions characterized by disregulated immune states (e.g., autoimmune diseases). Specific combinations of dsRNA plus IL-2 significantly increase survival in human melanoma-bearing animals in part because of augmentation by dsRNA of lymphokine activated killer cells (LAK) which are first formed in response to IL-2 exposure. The invention has wide applicability to non-toxic, efficacious control of both human cancer and various human viral infections and immunoregulatory disorders.
Patent IL-88630-A (IL)
Title: Apparatus for molding ground meat and the like
IPC: A22C7/00
Filed: 1988-12-08
Abstract: A molding apparatus particularly adapted to be associated to a meat chopper to mold the extruded ground meat into hamburgers. The said apparatus is provided with a feeler or sensor (27) which disactivates the meat chopper when a hamburger has been formed and which re-activates said meat chopper when the emptied mold (1) is re-introduced into the formation chamber (4). The feeler or sensor is mounted on the housing or body of the meat chopper so as to be self-adjustable as to its spacing from the formation mold when the positioning of the molding apparatus of the invention changes due to the wear of the meat chopper knives.
Patent IL-94712-A (IL)
Title: Polysaccharide-bound crownethers and compositions containing them for removing or inactivating harmful components in blood or other extracellular body fluids
Inventor: HENRY MARINUS CHRISTENSEN
IPC: B01J20/32
Filed: 1990-06-13
Abstract: A composition for removing or inactivating harmful components including virus from blood or other extracellular liquids comprises a crown ether compound substituted on a polysaccharide, preferably dextran. The composition may be soluble in water, preferably for intraveneous application, or insoluble for extracorporeal application.
Patent IL-99460-A (IL)
Title: High absorbency alginate fabric, its use as wound and burn dressing and its preparation
IPC: D04H1/42
Filed: 1991-09-12
Abstract: A non-woven fabric of alginate staple fibres comprising a mat of alginate staple fibres wherein said fibres are entangled through from 60% to 99% of the thickness of said mat, wherein the absorbency of the fabric is greater than 25.0g of deionized water per gram of fabric, said absorbency determined by contacting the fabric with a first end of a water absorbent strip, wherein a second end of the water absorbent strip contacts a deionized water source.
Patent IL-99633-A (IL)
Title: Elevating and lowering apparatus
IPC: A62B1/06
Filed: 1991-10-02
Abstract: The rope lifting and lowering apparatus has a base plate (1) to which a rope lowering pulley (2) mounted in a freely rotating manner and having a pawl stop is fastened. A toothed ring (7) is fastened to the side of the rope lowering pulley facing the base plate. The teeth (7a) of the toothed ring (7) interact with a pawl (9) in such a way that in the free-wheeling direction the pawl is lifted and in the locking direction the pawl clamps the toothed ring or the rope lowering pulley in position. The pawl is let into the base plate. <IMAGE>
Patent JP-S56109231-A (JP)
Title: Rubber composition suitable for tire
Inventor: FUJIMAKI TATSUO
IPC: B60C1/00
Filed: 1980-02-01
Abstract: PURPOSE: The titled composition with escellent wetskid characteristics, exothermic characteristics, etc., which comprises a styrene-butadiene copolymer rubber of a specified property, an amorphous 1,2-polybutadiene and a cis-1,4-polybutadiene in a specified weight ratio.  
     CONSTITUTION: The purpose rubber composition is obtained by compounding (A) a styrene-butadiene copolymer rubber containing 10W35wt% styrene, (B) an amorphous 1,2-polybutadiene having 60wt% or more 1,2-linkage and (C) a 1,4- polybutadiene having 80wt% or more cis-1,4 linkage, in a weight ratio of A+B/C of 25/75W75/25 and a weight ratio of A/B of 75/25W25/75. The composition has characteristics, which simultaneously satisfies requirements for slip resistance on a wet road, and low exothermic property during run, required for a tire to safely run a car. 
     COPYRIGHT: (C)1981,JPO&Japio
Patent JP-H06224199-A (JP)
Title: Forming method for bump
Inventor: ICHIKAWA IWAO
IPC: H01L21/60
Filed: 1993-01-25
Abstract: PURPOSE:To obtain a forming method for bumps wherein the forming process for metallic bumps is very simple and can be performed in a short time, and the equipment cost accompanied by the formation of the bumps can be made very low. CONSTITUTION:In a plurality of recessed parts 7 provided on a bump-particle receiving plate 6, particle-like solder bumps 8 are put respectively. Then, barrier metal films 3 laid on electrode pads 2 of a semiconductor substrate 1 are superimposed on the respective solder bumps 8 opposed thereto which are put on the bump-particle receiving plate 6. In this state, the semiconductor substrate 1 is heated, and the fused solder bumps 8 are formed by deposition on the side of the barrier metal films 3.
Patent JP-H0214092-A (JP)
Title: Device for discharging aggregate by rotary siphon from steam heating type drying cylinder, etc.
Inventor: ROOBERUTO BUORUFU
IPC: D21F5/10
Filed: 1989-01-20
Abstract: PURPOSE: To reduce the amount of steam required for dewatering by arranging a guide means, in which a steam/condensate mixture flowing into a condensate is rotated in a stand pipe around the axis, in a suction mouthpiece region. CONSTITUTION: A guide metal thin plate 20 as a guide means is arranged to a suction mouthpiece portion 17 of a condensate standpipe 14, A fixed angular momentum is imparted to a steam/condensate mixture flowing into a flow in gap. The steam/condensate mixture is caused to helically flow through a condensate standpipe 14, the condensate is effectively discharged from a drying cylinder by a steam.
Patent JP-S57127472-A (JP)
Title: Method for repairing worn part of table roller
Inventor: IKUSHIMA YOSHIZOU
IPC: B05D1/08
Filed: 1981-01-28
Abstract: PURPOSE: To form smooth melt sprayed films of high degrees of adhesion and to reduce costs through recovering of melt spraying powder by providing an enclosure which is opened above and backward above a roller to be repaired, and performing melt spraying work on the inner side thereof.  
     CONSTITUTION: In a roller 1, constant surplus width parts C are taken on both sides of a worn part B including local wear 3 by shape steel, and the range of A including these is finished by grinding. An enclosure 4 consists of side plates 5, 6 and a front vertical plate 7 having the height of the extent of not allowing the scattering of melt spraying powder. A notch 8 of the arc shape of the same diameter as the outside diameter of the roller 1 is provided to the bottom edges of the plates 5, 6, and a bottom plate 9 is fitted between the front end of the notch 8 and the plate 7. This enclosure 4 is erected by fixing the same to an apron table 12 by means of magnets 11, and the notch 8 is brought into opposite contact with the surplus width parts finished by grinding of said roller. Thence, a melt spraying torch 13 is inserted into the enclosure 4, and while the roller 1 is rotated, it is subjected to thermal spray overlaying. 
     COPYRIGHT: (C)1982,JPO&Japio
Patent JP-H10202353-A (JP)
Title: Forming die device for product having female screw
Inventor: SHIBATA KAZUYASU
IPC: B22D17/22
Filed: 1997-01-23
Abstract: PROBLEM TO BE SOLVED: To effectively cast and form a product with comparatively simple constitution without specially needing secondary work to a formed female screw hole part. SOLUTION: A core 3 for forming the female screw hole part projecting plural female screw forming parts 32a, 32b... engraving a male screw 33 on the outer peripheral surface as radiating state with equal interval, is arranged at either one of a movable die 1a or a fixed die 1b. The female screw forming parts are arranged so as to be rotatable in the peripheral direction in a die cavity 2 and also, at the movable die or the fixed die side which does not arrange the core for forming the female screw part, formed projecting parts 7a, 7b... for forming a part of the female screw hole H fitted to gap in each female screw forming part, are projectedly arranged.  Each female screw forming part of the core for forming the female screw part is rotated in the peripheral direction so that the female screw forming part formed with the other female screw forming part is passed through at least at one time.
Patent JP-2000209918-A (JP)
Title: Apparatus for gathering leavings of crop
Inventor: KITA TAKESHI
IPC: A01D51/00
Filed: 1999-01-19
Abstract: PROBLEM TO BE SOLVED: To efficiently gather the leavings of crops buried in the soil of a field. SOLUTION: A conveying conveyer means 5 is disposed in a traveling machine body 1 so that the front end in the progressing direction may be lowered and the rear end may be heightened. Tines 9 for scooping up the leavings 25 of crops from the field are installed in the conveying conveyer means 5. A gathering bucket 17 is installed at the rear part of the conveying conveyer means 5, and a digging blade body 15 for digging up the soil in front of the front end of the conveying conveyer means 5 is disposed in the traveling machine body 1.
Patent JP-H04218328-A (JP)
Title: Method and apparatus for forming sausage into continuous string and for separating its string into groop of each sausage or into groop of sausage mutually connected
Inventor: GEORUKU SHIYUTAUDENRAUSHIYU
IPC: A22C11/10
Filed: 1991-01-31
Abstract: PURPOSE: To exactly separate sausage or its group by separating the sausage through a separating element to rotate on specified conditions and varying the rotating speed of this element within an inactive rotation range but matching this speed with carrying speed within an active engage range. CONSTITUTION: In order to set the separating element of a separator such as a blade 22, for example, at the exact position of a squeezed section between adjacent sausages 13, the operation of the separating element is controlled synchronously or proportionally with the operation of a compressing element 9. The rotating speed of a separating arm 20 or the compressing element 9 is controlled almost corresponding to the carrying speed of an endless belt 10 only at the moment of separating operation or previous dividing operation. This synchronous operation is performed when the separating arm or the compressing element is positioned obliquely while facing the squeezed section between respective two sausages. On this stage, the blade 22 is accepted at the squeezed section between two sausages and rotated later almost synchronously with the carrying speed of sausages.
Patent JP-H09204155-A (JP)
Title: Portable information processor
Inventor: TOYONAGA MASAHIKO
IPC: G06F15/02
Filed: 1996-01-25
Abstract: PROBLEM TO BE SOLVED: To improve the cost, power consumption, and operability of a portable information processor by making good use of advantages of a monochromatic liquid crystal display and a color liquid crystal display. SOLUTION: A notebook type personal computer is provided with a monochromatic liquid crystal display part 1 and a color liquid crystal display part 2 which is mounted on its back. The monochromatic liquid crystal display part 1 and color liquid crystal display part 2 are fitted to a display frame through a rotary joint part 12 so that they can rotate in one body. A display switching control part which is built in an information processing part 3 having a keyboard part 11 drives only the monochromatic liquid crystal driving part 1 when the monochromatic liquid crystal display part 1 appears in the front or the color liquid crystal display part 2 when the color liquid crystal display part 2 appears in the front being associated with the rotary joint part 12.
Patent JP-H11210759-A (JP)
Title: Conical roller bearing
Inventor: YAMAMOTO KENJI
IPC: F16C33/46
Filed: 1998-01-23
Abstract: PROBLEM TO BE SOLVED: To permit the breaking-in rotation of conical rollers while applying the required pressures to all of the conical rollers to install a conical roller bearing in a short time by subjecting a holder to a simple improvement in shape. SOLUTION: In a conical roller bearing assembled by fitting an outer ring 5, from the direction of an axis, over a group of conical rollers 3 fitted into a raceway groove 2 in an inner ring 1 and held aligned in a holder 4, the holder 4 is provided with projecting parts 8 to which the outer ring 5 abuts before abutting to the conical rollers 3 during an assembling process. Thus during the process of incorporating the outer ring 5, the outer ring 5 is made to abut to the projecting parts 8 of the holder 4 before abutting to the conical rollers 3, permitting all the conical rollers 3 to be aligned at the same time via the holder 4 and be pressed against the large-diameter flange part 2a of the inner ring 1.
Patent JP-S60166303-A (JP)
Inventor: ETOGARU FUITSUSHIYAA
IPC: C08B37/00
Filed: 1985-01-25
Abstract: (57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。
Patent JP-S61170713-A (JP)
Title: Minute gap adjusting device
Inventor: YOSHIDA SATOAKI
IPC: G05G23/00
Filed: 1985-01-24
Abstract: PURPOSE:To form and adjust a minute gap by a manual operation, by providing a spherical body, an energizing means for energizing this spherical body, and a mechanism for adjusting a position of the spherical body energized by the energizing means, in the direction parallel to the end face, between each opposed end face of the first and the second moving plates. CONSTITUTION:A position of the first moving plate 3 to a base 1 is fixed by clamping a screw 9. Subsequently, a roller 23 is moved forward by operating an air cylinder 25 and a photosensor plate 6 is chucked by chuck levers 24, 24. When the photosensor plate 6 is set to a freely movable state by loosening screws 7, 7, and its head is moved back by operating a micrometer head 13, a spherical body 11 moves to the right. An end face 3b of the first moving plate 3 and an end face 4a of the second moving plate 4 make an angle theta, therefore, the second moving plate 4 is displaced in the direction as indicated with an arrow B, by tan theta times of a moving extent of the spherical body 11. In this state, a position of the photosensor plate 6 is adjusted by operating an X-Y table base 15, and thereafter, by clamping the screws 7, 7, the photosensor plate 6 is fixed to a pickup body 5 in a prescribed position relation.
Patent JP-H08202779-A (JP)
Title: Device and method for processing preparation of input/ output form
Inventor: KUNIMOTO TAKESHI
IPC: G06Q10/10
Filed: 1995-01-27
Abstract: PURPOSE: To display an input/output form on a display screen as the image of a preparing person and to customize the automatic preparation of the input/ output form concerning the device and method for processing preparation of input/output form to be used for inputting data to a computer or outputting data from the computer. CONSTITUTION: The basic layout image of the input/output form combining parts such as input/output items is reduced by a form selecting processing part 2, plural images are simultaneously displayed on the display screen, and any one image is selected out of them by the preparing person. At an item selecting processing part 3, parts presented in the basic layout image are selected, data items are allocated to the respective selected parts, and a prototype is prepared. At a layout pallet processing part 4, the prototype is worked and the input/ output form is prepared as imaged by the preparing person. At a definition table preparing part 5, a definition table for defining various kinds of information of the input/output form is prepared.