baber/WOPTO huggingface dataset:
Patent CA-2439301-A1 (CA)
Title: Compositions comprising matrine and dictamnine for treating or preventing cancer and other diseases
Inventor: SMIT FRISI HOBBE
IPC: A61K36/8945
Filed: 2002-02-26
Abstract: The present invention is concerned with the treamtment or prevention of cancer, H. pylori infections, chronic inflammatory conditions, cardiovascular diseases or cerebral vascular diseases in a mammal, comprising the administration of the mammal of an effective amount of a composition containing a matrine component and dictamnine. Another aspect of the invention relates to a composition comprising at least 15 µmole of a matrine component and at least 0.15 µmole of dictamnine.
Patent CA-2439415-A1 (CA)
Title: Cathepsin cysteine protease inhibitors
Inventor: ROBICHAUD JOEL STEPHANE
IPC: C07D295/135
Filed: 2002-03-01
Abstract: This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
Patent CA-2442542-A1 (CA)
Inventor: MARTENS FRANCISCUS JOHANNA ARN
IPC: C02F11/12
Filed: 2002-03-28
Abstract: L'invention concerne un procédé d'oxydation partielle d'un gaz ou d'un liquide hydrocarboné, caractérisé en ce que, dans une première étape, on procède à l'oxydation partielle et à l'élimination de la suie par formation d'une suspension comprenant de l'eau et du carbone provenant du produit d'oxydation gazeux, et en ce que, dans une seconde étape, on sépare une partie de l'eau de la suspension, de manière à obtenir une composition de suie renfermant moins d'eau, la séparation se faisant au moyen d'une centrifugeuse décanteuse.
Patent CA-2443114-A1 (CA)
Inventor: TANIZAKI SHINICHIRO
IPC: C08J7/044
Filed: 2002-04-03
Abstract: A laminated material having, on a substrate, a structure in which a gas-barrier intermediate layer formed by coating with a coating agent containing a water-soluble polymer is interposed between two thin deposition layers.
Patent CA-2444026-A1 (CA)
Title: Mutants of desoxycytidine kinase having extended enzymatic activity
Inventor: MARLIERE PHILIPPE
IPC: A61K48/00
Filed: 2002-04-10
Abstract: The invention relates to a method for artificial in vivo evolution of proteins, said method making it possible to bring about the evolution of a protein X by complementation of a relative protein Y,X and Y both belonging to the same class of enzyme commission (EC) nomenclature or belonging to related classes. The mutants D133E and R104Q of desoxycytidine kinase (DCK) were obtained; both of said mutations result in acquisition of thymidine kinase activity by DCK.
Patent CA-2447475-A1 (CA)
Inventor: XUE CHU-BIAO
IPC: A61P1/04
Filed: 2002-05-23
Abstract: The present application describes novel hydantoin derivatives of formula (I), or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, R1, R2, R3, R4, R5, R6, R7, R11, and n are defined in the present specification, which are useful as inhibitors of matrix metallproteinases (MMP), TNF-.alpha. converting enzyme (TACE), aggrecanase, or a combination thereof.
Patent CA-2451480-A1 (CA)
Title: Pto shaft brake
Inventor: VISWANATHAN HARIHARAN
IPC: F16D63/00
Filed: 2003-11-28
Abstract: A spring loaded snubber brake is provided for a Power Take Off (PTO) shaft of a tractor. The brake is carried by the PTO shaft and utilizes the centrifugal force created by the spinning shaft to become disengaged as the shaft rotates and become engaged as the shaft is declutched. Since the brake does not apply any frictional force on the shaft as it rotates, there is no parasitic loss of PTO  output horsepower. As the shaft is declutched and comes to rest, the brake springs urge it into engagement with the shaft to prevent inadvertent rotation of the shaft due to residual forces produced by hydraulic fluid forces operating on the PTO drive components.
Patent CA-2451649-A1 (CA)
Title: Temperature probe adapter
Inventor: YERLIKAYA Y DENIS
IPC: G01K7/00
Filed: 2002-03-28
Abstract: An electronic thermometer that reduces patient exposure to all sources of cross-contamination, aids in infection control, and provides a clean, uncontaminated, readily accessible source of probe covers. A probe assembly for an electronic thermometer, which does not require expensive calibration procedures during manufacturing and allows the use of inexpensive thermisters.  A memory component such as an EEPROM integrated circuit stores calibration information and identifying information in each particular probe assembly which improves performance and reduces manufacturing costs.
Patent CA-2453827-A1 (CA)
Inventor: BOEGLI CHARLES
IPC: B29L7/00
Filed: 2003-12-22
Abstract: The device for satinizing and embossing flat materials comprises an embossing roll and at least one mating roll, said rolls being connected to a driving system and adapted to be driven individually or in common and to be resiliently pressed against one another while the individual teeth are flattened, and the embossing teeth being designed such as to produce in the corresponding locations of said flat material (9) during its passage embossed marks whose appearance varies according to the viewing angle of the observer and/or the kind and/or the position of the lighting source, the embossing teeth which produce said variable marks having a different geometrical shape and/or surface than the satinizing teeth intended for satinizing. To this end, the surfaces of said embossing teeth (2S1 - 2S6, 2M1 - 2M3) and/or portions of the tooth space bottom (ZG) are provided with microstructures (20 - 22), 26 - 33; 23 - 25). These microstructures allots producing largely forgery-proof marks which may furthermore provide a very decorative effect.
Patent CA-2454297-A1 (CA)
Title: Procede et systeme de mesure de la duree d'une zone incluse dans une suite d'images
Inventor: MUENCH MARK S
IPC: G06T7/60
Filed: 2001-08-16
Abstract: L'invention porte sur un système et un procédé de calcul de la durée d'une zone cible incluse dans une suite d'images, ce procédé utilisant un modèle tridimensionnel d'au moins une zone cible dans un site. Un compteur est incrémenté sur des périodes, par exemple, sur une base trame par trame, lorsque la zone cible est incluse dans la suie d'images. Un paramètre d'occlusion est calcul pour ajuster la durée calculée indiquant que la zone cible est incluse dans la suite d'images. Le paramètre d'occlusion facilite la comptabilisation des variations dans une obstruction de zone cible et est utilisé pour faire des ajustements sur un compteur de sorte qu'un nombre indiquant une durée soit le reflet des variations d'obstructions de la zone cible. Un paramètre prioritaire associé à une zone cible est calcul pour ajuster la durée calculée de la zone cible. Le paramètre prioritaire facilite la comptabilisation des variations de la représentation d'une image incluse dans la zone cible obtenue par diverses caméras à focale variable.
Patent CA-2456014-A1 (CA)
Inventor: GAGNER PATRICK
IPC: F16B1/00
Filed: 2004-01-15
Abstract: Le dispositif retient un fiasque (36) contre un disque (10) présentant dans sa face radiale (14) un évidement annulaire (16) délimité par plusieurs parois dont l'une (24) est formée par une face d'une bride (26), ledit fiasque présentant une base annulaire (40) en appui contre la paroi radialement extérieure (18) de l'évidement et un pied (42) qui s'étend dans l'évidement à partir de la base, ledit dispositif comportant une bague de retenue annulaire (44) fendue disposée dans l'évidement. De façon caractéristique, ladite bride présente une extrémité supérieure de contour festonné munie d'au moins une encoche (29), ledit le pied est muni d'un rebord avant (62) de contour festonné, muni d'au moins une entaille (82), et d'un rebord arrière (64) entre lesquels est formée une gorge annulaire (66) destiné â loger la bague qui présente un tenon (54) axial apte à pénétrer dans ladite encoche et dans ladite entaille.
Patent CA-2457918-A1 (CA)
Inventor: SEIFER DAVID B
IPC: A61K38/22
Filed: 2002-08-20
Abstract: La présente invention concerne des méthodes et du matériel permettant d'évaluer la réserve ovarienne et d'estimer la réponse ovarienne à des traitements contre la stérilité chez une femme. Les taux sériques de MIS présentent une corrélation positive avec la production et l'extraction d'ovocytes mûrs et servent d'indicateurs pronostiques de la réponse de la femme au traitement contre la stérilité. Les taux de MIS peuvent être surveillés avant et pendant le traitement contre la stérilité et sont utiles pour régler le rythme et la dose des traitements de manière à obtenir un résultat optimal chez des patientes, à éviter l'hyperstimulation ovarienne, ou à indiquer l'annulation d'un traitement non réussi. La MIS peut également être administrée aux femmes pour stimuler le développement de follicules et pour prévenir la déplétion de la réserve ovarienne.
Patent CA-2459383-A1 (CA)
Inventor: HEPLER EDWARD L
IPC: H03M13/39
Filed: 2002-04-15
Abstract: The sliding window approach to pipeline maximum a posteriori (MAP) decoder architecture is modified to decrease processing time. Once the forward metrics have been calculated for the first sliding window of the decoder, the reverse metrics for each window are calculated while the forward metrics for the next window are calculated. As each new forward metric is calculated and stored into memory (14), the forward metric from the previous window is read from memory (14) for use with reverse metric being calculated in calculating extrinsic value. Each forward metric for use in calculating an extrinsic value is read from memory on the same clock edge that the new forward metric is written to the same memory location. Although this architecture was developed for a turbo decoder, all convolution codes can use the MAP algorithm of the present inventioon.
Patent CA-2460333-A1 (CA)
Title: New pet food composition and method
Inventor: CHEUK WAI LUN
IPC: A23K1/14
Filed: 2002-09-24
Abstract: A tanine pet food composition comprising a meat based material having an essentially solid mass assuming the shape of the container in which it is packed, said pet food having meat particles with a moisturized appearance and visually recognizable discrete food particles upon slicing the pet food mass after departure from the said container.
Patent CA-2467431-A1 (CA)
Inventor: KONO YASUHIKO
IPC: B60C23/02
Filed: 2002-11-14
Abstract: L'invention concerne un capteur de pression des pneus pouvant être alimenté par voie radio par des unités montées sur la carrosserie d'un véhicule. Les capteurs de pression (10 (10a-10d)) montés sur les pneus (2 (2a-2d)) sont alimentés, par voie radio, par des unités d'alimentation sans contact (40 (40a-40d)) disposées sur la carrosserie du véhicule. La transmission d'énergie se fait par couplage électromagnétique ou par hyperfréquences. Un capteur de pression (10) comprend une unité de réception d'énergie sans contact qui produit un courant continu sur la base de l'énergie fournie par une unité d'alimentation en courant continu sans contact (40), permettant de fournir l'énergie nécessaire au fonctionnement du capteur de pression (10). Le capteur de pression (10) permet de détecter la pression de l'air ou analogue dans le pneu et de transmettre les mesures, par voie radio, à un dispositif récepteur (20).
Patent CA-2468636-A1 (CA)
Title: Elastomeric compositions
Inventor: WADDELL WALTER H
IPC: C08F8/20
Filed: 2002-12-09
Abstract: The present invention includes compositions suitable for air barriers such a s innerliners where adhesion to tire carcass materials (e.g., SBR) and flexibility are desirable, as well as low air permeability. The invention includes a tire innerliner made by combining a filler; a sulfur cure system; optionally at least one secondary rubber; and at least one halogenated terpolymer of C4 to C8 isoolefin derived units, C4 to C14 multiolefin derive d units, and p-alkylstyrene derived units. Examples of suitable fillers includ e modified carbon black, carbon black, silica, exfoliated clays, and combinations thereof. The present invention also includes a method of producing an elastomeric terpolymer composition comprising combining in a diluent C4 to C8 isoolefin monomers, C4 to C14 multiolefin monomers, and p- alkylstyrene monomers in the presence of a Lewis acid and at least one initiator to produce the terpolymer. Examples of suitable initiators include cumyl compounds and or halogenated organic compounds, especially secondary o r tertiary halogenated compounds such as, for example, t-butychloride, 2-acety l- phenylpropane (cumyl acetate), 2-methoxy-2-phenyl propane (cumylmethyl-ether ), 1,4-di(2-methoxy-2-propyl)benzene(di(cumylmethyl ether)); the cumyl halides, particularly the chlorides, such as, for example 2-chloro-2-phenylpropane, cumyl chloride (1-chloro-1-methylethyl)benzene), 1,4-di(2-chloro-2- propyl)benzene (di(cumylchloride)), and 1,3,5-tri(2-chloro-2propyl)benzene (tri(cumylchloride)); the aliphatic halides, particularly the chlorides, suc h as, for example, 2-chloro-2,4,4-trimethylpentane (TMPCI), and 2-bromo-2,4,4- trimethylpentane (TMPBr).
Patent CA-2468930-A1 (CA)
Title: Methyl acrylate-diamine based polyamide resins and processes for producing the same
Inventor: STAIB RONALD R
IPC: C08G73/02
Filed: 2002-12-20
Abstract: The present invention contemplates poly(aminoamide) pre-polymers, polyamide polymers, a multi-step process for the synthesis of these pre-polymers and polymers using acrylates and at least one monomer containing at least two primary amines, and the resins resulting from the reaction of the polymers with an epihalohydrin. These resins may be used as wet strength resins and creping aids in the papermaking industry as well as surface additives for wool.
Patent CA-2470303-A1 (CA)
Title: Media and methods for promoting maturation of conifer somatic embryos
Inventor: GUPTA PRAMOD
IPC: C12Q1/68
Filed: 2004-06-08
Abstract: In one aspect, the present invention provides methods for producing mature conifer somatic embryos. The methods of the invention comprise the steps of:  (a) culturing pre-cotyledonary conifer somatic embryos in, or on, a development medium comprising less than 0.5% of gellan gum to form cotyledonary conifer somatic embryos; and (b) culturing cotyledonary conifer somatic embryos formed in step (a) in, or on, a maturation medium comprising between about 0.5% to about 1.5% of gellan gum to form mature conifer somatic embryos. In some embodiments, the maturation medium further comprises sucrose and/or abscisic acid.
Patent CA-2470930-A1 (CA)
Inventor: KANNAPEL TIMOTHY H
IPC: G06F40/00
Filed: 2003-08-21
Abstract: A method of analyzing electronic ink, in which document data for a document containing electronic ink content is received from a software application running on a first processing thread. The first processing thread is employed to provide the document data to an electronic ink analysis process for analyzing on a second processing thread. Control of the first processing thread is then returned to the software application. After the results of the analysis are received, the results are reconciled with the current document data for the document.
Patent CA-2472049-A1 (CA)
Title: Dominant negative proteins and methods thereof
Inventor: TANSEY MALU LOURDES G
IPC: A61K38/00
Filed: 2003-01-06
Abstract: The invention relates to novel proteins with TNFSF antagonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of TNFSF-related disorders.
Patent CA-2472956-A1 (CA)
Inventor: WANG YU-CHANG JOHN
IPC: A61K33/24
Filed: 2003-02-14
Abstract: The invention relates to stabilized formulations of therapeutically active peptides, particularly PACAP 66. Formulations of the invention include a peptide containing at least one histidine residue, a transition metal salt and an organic solvent. The above formulations may contain peptides that have at least one asparagine residue and are acidified and dried (such as spray-dried or freeze-dried) before formulation preparation. Other formulations of the invention relate to stabilized formulations of PACAP 66 or peptides containing an asparagine residue, which are acidified and dried (such as spray-dried or freeze-dried) with or without a transition metal salt.
Patent CA-2478821-A1 (CA)
Title: Aliment pour especes aquatiques
Inventor: KULAS ELIN
IPC: A23K1/18
Filed: 2003-03-11
Abstract: L'invention concerne un aliment pour les espèces aquatiques et les crustacés, et plus particulièrement pour les espèces marines et leurs alevins. L'aliment décrit contient des protéines, des lipides et d'autres ingrédients facultatifs, et se caractérise en ce que les lipides sont constitués d'une ou de plusieurs huiles marines et/ou huiles végétales traitées avec de l'urée et/ou d'autres amines ou amides, pour prévenir toute dégradation par oxydation (stress oxydatif).
Patent CA-2482341-A1 (CA)
Inventor: RECEVEUR JEAN-MARIE
IPC: C07D207/09
Filed: 2003-04-08
Abstract: Novel compounds of Formula (I) which modulate MCH activity are disclosed, in which A is a linker; Ar1 is an aryl or heteroaryl group; R1 is a lower alkoxy group; R2 is an R1 group or hydrogen, an OH or an NH2 group, Q together with the carbonyl forms an amide group, which is further substituted with an amine group; R5 is selected from hydrogen, halogen atoms, alkoxy groups, hydroxy, alkylamino groups, dialkylamino groups, hydroxylalkyl groups, carboxamido groups, acylamido groups, acyl groups, -CHO, nitrile, alkyl, alkenyl or alkynyl groups, -SCH3, partially or fully fluorinated alkyl, alkoxy or thioalkoxy groups such as -CH2CF3, -CF2CF3, -CF3, -OCF3, -SCF3; -SO2NH2, -SO2NHAlk, -SO2NAlk2, -SO2Alk; X is H, F, Cl, Br, I, -SCH3, -CF3, -OCF3, -SCF3, OCH3, or lower alkyl or alkenyl group; R8 is halogen atoms, alkyl, alkenyl or alkynyl groups, cycloalkyl groups, aryl groups, heteroaryl groups, heterocyclyl groups, alkylcycloalkyl groups, alkylaryl groups, alkylheterocyclyl groups, alkylheteroaryl groups, arylalkoxy groups, aryloxy groups, alkoxy groups, dialkylamino groups, -CONHAlk, -CONHAr, -CONAlk2, -NHCO-Alk, -NHCO-Ar, -CO-Alk, -CO-Ar, -SCH3, partially or fully fluorinated alkyl, alkoxy or thioalkoxy groups; or R8 is R6-Ar2-B-, in which B is a single bond or a connecting moiety; Ar2 is an Ar1 group; R6 is an R5 group; and which are useful in the treatment or prevention of e.g. obesity, depression, diabetes, bulimia etc.
Patent CA-2483528-A1 (CA)
Inventor: ARAI MIKIYA
IPC: C23C26/00
Filed: 2003-10-09
Abstract: With a rotor such as a moving blade and a discharge electrode containing a hard material such cBN kept in a working liquid or a gas, a pulse-like discharge is generated by a discharging power supply between the tip end of the rotor and the discharge electrode to thereby melt the discharge electrode and deposit part of thereof onto the tip end of the rotor, whereby an abrasive coating containing a hard material such as cBN is formed.
Patent CA-2483911-A1 (CA)
Inventor: GLANDORF WILLIAM MICHAEL
IPC: A61K8/365
Filed: 2003-05-09
Abstract: L'invention concerne des compositions et des méthodes servant à traiter et à modifier des surfaces et à administrer plus efficacement des agents actifs à des surfaces traitées par ces compositions. Ces compositions contiennent des polymères à base de siloxanes fonctionnalisés par des fragments latéraux comprenant des groupements anioniques et plus précisément des groupements d'acide carboxylique. Lorsqu'elle est appliquée sur une surface adaptée, la présente composition contenant des polymères à base de siloxanes fonctionnalisés par des groupements carboxy forme une couche sensiblement hydrophobe sur la surface traitée. Ces polymères se déposent efficacement sur les surfaces comprenant des sites cationiques, capables de former des liaisons chimiques avec les groupements anioniques du polymère. La surface traitée devient hydrophobe en raison de la couche déposée de polymère à base de siloxanes fonctionnalisée par des groupements carboxy, ce qui offre certains avantages à la surface traitée, tels qu'un nettoyage plus facile, une élimination et une prévention des taches, un blanchiment des dents, etc.. Le polymère à base de siloxanes fonctionnalisé par des groupements carboxy permet également d'amener et de déposer les agents actifs sur la surface traitée et d'améliorer la fixation et l'efficacité de ces agents actifs sur la surface traitée. Les présentes compositions sont destinées à être utilisées dans un grand nombre d'applications, notamment les soins buccaux, les soins capillaires et cutanés, les soins personnels, les cosmétiques et les produits servant au nettoyage et au traitement de tissus ou de surfaces dures. Les exemples de l'invention comprennent des compositions orales destinées à être utilisées pour nettoyer et blanchir les dents et les prothèses dentaires, pour prévenir, réduire ou éliminer la plaque dentaire, les calculs et les taches qui se déposent à la surface des dents, et pour rendre les dents brillantes et lisses et offrir une sensation agréable. Les compositions renferment au moins 0,1 % en masse environ d'un polymère à base de siloxanes fonctionnalisé par des groupements dicarboxy contenu dans une préparation permettant de déposer efficacement le polymère sur les dents et d'autres surfaces de la cavité buccale.
Patent CA-2484054-A1 (CA)
Inventor: ZABRISKIE BRIAN S
IPC: H02H3/093
Filed: 2004-10-07
Abstract: An overcurrent protective relay includes means for obtaining current values from a power line which are adjusted for application to and use by a processor portion of the relay. The processor evaluates the adjusted power line current values against an overcurrent curve by which, as the current increases from a continuous rating, the time to trip decreases.  A thermal limit I2t curve is combined with the time overcurrent curve, the curves being arranged so that the thermal limit curve crosses over the time overcurrent curve at a selected current value. In such a case, the thermal limit curve controls the time to trip for current fault values above the selected current value and the inverse time overcurrent curve controls the time to trip for fault current values below the selected current value.
Patent CA-2484232-A1 (CA)
Title: Systems and methods for reducing satellite feeder link bandwidth/carriers in cellular satellite systems
Inventor: KARABINIS PETER D
IPC: H04B7/216
Filed: 2003-05-28
Abstract: Information content is nonidentically mapped between service link carriers (130) and feeder link carriers (140) at a cellular satellite (100). A reduced number of satellite feeder link carriers compared to the number of satellite service link carriers and/or a reduced total bandwidth of the satellite feeder link carriers compared to the satellite service link carriers thereby may be obtained.
Patent CA-2484913-A1 (CA)
Title: System and method for pre-qualification of telephone lines for dsl service using an average loop loss
Inventor: AFZAL MUHAMMAD A
IPC: H04M3/30
Filed: 2003-06-12
Abstract: A system and method for testing lines in a network. The system and method are described in connection with a system for use with a telephone network to aid a network operator determine whether the any line can support high speed data services. According to the method, a mapping is created between low frequency measurements and average loop loss over a high frequency range. The average loop loss is sued to compute the equivalent working length of a line, which is an industry standard measure of the ability of a line to support high speed data services.