baber/WOPTO huggingface dataset:
Patent AU-2021341483-A1 (AU)
Title: Use of active substances with antiviral, anti malarial, and/or mucolytic properties in the treatment of viral lung diseases including covid-19 by soft mist inhaler or vibration mesh technology nebulizer through inhalation route
Inventor: PEKOZ AYCA YILDIZ
IPC: A61K9/12
Filed: 2021-07-14
Abstract: The present invention relates to the administration of active substances with antiviral, antimalarial and/or mucolytic properties, or pharmaceutically acceptable derivatives thereof for the treatment of viral lung diseases, especially COVID-19 by means of soft mist inhaler or vibrating mesh technology (VMT) nebulizer through inhalation. The present invention particularly relates to the administration of favipiravir, mannitol, hydroxychloroquine, umifenovir, molnupiravir, pimodivir, and/or remdesivir, and/or their water-soluble salt forms, and/or their water-soluble cyclodextrin complexes, and/or their water-soluble forms obtained by water-solubility increasing methods in the treatment of viral lung diseases, especially COVID-19 by means of soft mist inhaler or vibrating mesh technology (VMT) nebulizer through inhalation. Active substances with antiviral, antimalarial, and/or mucolytic properties reach the lungs efficiently and quickly, and local pulmonary administration is performed such that it provides an effective treatment. Since the drug is targeted directly to the lungs without getting into systemic circulation via local (direct) administration, its concentration is higher at the application region, thereby reducing the side effects and costs per application of the drug, and increasing its efficacy.
Patent AU-2021357081-A1 (AU)
Title: Potent and selective inhibitors of her2
Inventor: GRAY NATHANAEL S
IPC: A61K31/40
Filed: 2021-10-04
Abstract: Disclosed are compounds and pharmaceutically acceptable salts and stereoisomers thereof that that are potent and selective inhibitors of HER2. Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds to treat diseases and disorders associated with HER2.
Patent AU-2021360193-A1 (AU)
Title: Composition
Inventor: LAGUERRE MICHAEL
IPC: C11B3/00
Filed: 2021-10-12
Abstract: The present invention is related to extracts rich in polar lipids obtained or obtainable from macroalgae, microalgae, photosynthetic bacteria and/or photosynthetic organ(s) and/or tissue(s) of a plant and combinations thereof as well as their uses as emulsifiers.
Patent AU-2021369170-A1 (AU)
Title: Wind turbine auxiliary power system
Inventor: CANALES SEGADE JOSE MARÍA
IPC: H02J3/38
Filed: 2021-10-12
Abstract: A wind turbine auxiliary power system is provided and is configured to receive electrical power from an electrical power generating system (110) of the wind turbine or from a power grid (200). The auxiliary power system (10) comprises an auxiliary transformer (20) having a primary side configured to be coupled to the electrical power generating system (110) of the wind turbine (100) and a secondary side configured to be coupled to auxiliary power consumers (60) of the wind turbine (100) and to provide transformed electrical power to the auxiliary power consumers (60). It further includes an electronic on-load tap changer (30) provided on the auxiliary transformer (20), wherein the electronic on-load tap changer (30) comprises taps (31) on at least one transformer winding (21, 22) of the auxiliary transformer (20) and semiconductor switches (32, 35, 36) that are coupled to the taps (31) and that are configured such that by controlling the semiconductor switches (32, 35, 36), the transformation ratio of the auxiliary transformer (20) is adjustable to compensate for voltage variations on the primary side of the auxiliary transformer (20).
Patent AU-2021374831-A1 (AU)
Title: Oral thin film
Inventor: MÜLLER MARKUS
IPC: A61P29/00
Filed: 2021-11-05
Abstract: Described is an oral thin film comprising at least one matrix layer, wherein the at least one matrix layer comprises at least one pharmaceutically active agent, at least one polyvinyl alcohol and at least one polyvinyl alcohol-polyethylene glycol graft copolymer, a method for producing same, and use thereof as a medicament.
Patent AU-2021382014-A1 (AU)
Title: Powered dental cleaning device
Inventor: BREWER GERALD K
IPC: A46B7/06
Filed: 2021-11-19
Abstract: Powered toothbrush systems that provide improved bristle positioning and bristle contact with tooth surfaces that reduce the time and effort required for effective brushing. Some embodiments use alternating or oscillating pneumatic pressure and suction to move a toothbrush head. Various configuration of the brush head provide different areas of coverage ranging from individual tooth to quarter mouth (U-cross section), to half (U-cross section or H-cross section) or whole mouth (U-cross section or H-cross section) coverage. Some embodiments include flexible fingers and/or bladders to keep the bristle tips properly engaged with the teeth and gums, providing bristle contact over a wide variety of malocclusion. The shape of the brush heads adapts to conform closely to the shape of the user's dental tray and to any malocclusion that may be present. The powered toothbrush automatically generates motion of the brush head that simulates the Modified Bass Method of brushing.
Patent AU-2021385062-A1 (AU)
Title: Fiber optic wetmate
Inventor: CASSIDY CHRISTOPHER
IPC: E21B21/01
Filed: 2021-11-18
Abstract: Systems and methods are provided to facilitate connection of multiple stage completions. A first completion stage is deployed at a wellbore location. Subsequently, the next completion stage is moved downhole into engagement with the first completion stage. The completion stages each have communication lines that are coupled together downhole via a wetmate connection. Debris prevention and removal devices and methods are also provided.
Patent AU-2021398541-A1 (AU)
Title: Pharmaceutical composition containing propofol, a cyclodextrin or a cyclodextrin derivative and a pharmaceutically acceptable salt
Inventor: BOUCHFAA MYRIAM
IPC: A61K47/69
Filed: 2021-12-10
Abstract: The present invention relates to a pharmaceutical composition comprising propofol and at least one cyclodextrin and/or a cyclodextrin derivative. Characteristically, according to the invention, it further comprises at least one pharmaceutically acceptable salt, with the exception of basic and/or acidic pharmaceutically acceptable salts.
Patent AU-2021401505-A1 (AU)
Title: High-hardness armored steel having excellent low-temperature impact toughness, and manufacturing method therefor
Inventor: YU SENG-HO
IPC: C22C38/58
Filed: 2021-11-04
Abstract: The present invention can provide armored steel having high hardness and excellent low-temperature impact toughness to provide excellent ferroelasticity, and a method for manufacturing same.
Patent WO-2022226599-A1 (WO)
Title: Procédé et système de transfert d'échantillon
Inventor: GUPTA VIPUL
IPC: G01N33/487
Filed: 2022-04-29
Abstract: La présente invention concerne des procédés et des systèmes pour le transfert d'échantillons collectés sur des écouvillons (ou des collecteurs d'échantillons similaires) sur des types particuliers de substrats pour une analyse ultérieure ou un autre traitement. Le procédé consiste à mettre en contact le collecteur d'échantillon contenant un échantillon comprenant la substance chargée avec la matrice d'électrophorèse ; appliquer un champ électrique à travers la matrice d'électrophorèse pour effectuer le transfert de la substance chargée du collecteur d'échantillon à la matrice d'électrophorèse. La présente invention concerne également des systèmes, des composants et des procédés utiles qui peuvent aider à améliorer les performances d'une opération sur des substances chargées au sein d'un système d'électrophorèse. De tels systèmes peuvent comprendre un premier réservoir d'électrolyte comprenant une première électrode ; un deuxième réservoir d'électrolyte comprenant une deuxième électrode ; un fil s'étendant entre les premier et deuxième réservoirs d'électrolyte ; un troisième réservoir à travers lequel passe le fil, et un contrôleur destiné à commander l'application d'un champ électrique à travers le fil de façon à effectuer le mouvement d'une substance chargée le long du fil. Le troisième réservoir peut être un réservoir de chargement d'échantillon destiné à charger un échantillon sur le fil, ou un réservoir d'opération à l'intérieur duquel une opération est effectuée sur la substance chargée. Le système permet à des substances chargées d'être prises le long du fil puis soumises à une opération à l'intérieur d'un réservoir dans un deuxième emplacement.
Patent AU-2022204499-A1 (AU)
Title: Improved prefabricated brick inlay panels
Inventor: GUBBINS CHARLIE
IPC: B28B7/00
Filed: 2022-06-24
Abstract: A form liner for inlaying relief elements onto which concrete is poured to form a precast 
concrete panel with surface relief texture, the form liner comprising a plurality of spaced-apart 
elongate strips of resilient protuberances on a planar surface, wherein in use the resilient 
protuberances sealingly and deformably receive and retain the relief elements on the planar 
surface.
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Patent AU-2022211378-A1 (AU)
Title: Peripheral anti-defocus optical devices
Inventor: TUNG HSIAO-CHING
IPC: G02C7/02
Filed: 2022-01-19
Abstract: A contact or spectacle lens for correcting peripheral ocular defocus which has a center zone in a central portion for correcting refractive errors and an aspheric, annular anti-defocus zone adjacent to and extending radially outwardly from the center zone. The vertical meridian of the anti-defocus zone is less aspheric than the horizontal meridian of the anti-defocus zone, and the horizontal and vertical meridians are blended with progressively changing e-values to form a smooth optical surface.
Patent AU-2022219681-A1 (AU)
Title: Antibodies against cd112r and uses thereof
Inventor: TSUKERMAN PINCHAS
IPC: C07K16/28
Filed: 2022-02-09
Abstract: The present invention provides monoclonal antibodies that recognize human CD112R with high affinity and specificity and inhibit its binding to Nectin-2. The present invention further provides pharmaceutical compositions comprising the antibodies and methods for their use in cancer immunotherapy and in diagnosis.
Patent AU-2022229339-A1 (AU)
Title: Engine and vehicle
Inventor: LIU MINGLIANG
IPC: F02F1/40
Filed: 2022-01-19
Abstract: An engine, which comprises a cylinder head and a cylinder body (12). A first water jacket channel (10), an exhaust channel, and a second water jacket channel (11) are provided in the cylinder head. The exhaust channel is arranged between the first water jacket channel (10) and the second water jacket channel (11). The first water jacket channel (10) and the second water jacket channel (11) are arranged in proximity to the exhaust channel. The first water jacket channel (10) is in communication with the second water jacket channel (11). The second water jacket channel (11) is in communication with the cylinder body (12). The second water jacket channel (11) is provided with a water inlet channel (14). During actual use, the first water jacket channel (10) and the second water jacket channel (11) absorb the heat of a high-temperature gas in the exhaust channel and that on the cylinder head, thus effectively reducing the temperature of the cylinder head, and providing the cylinder head with an improved cooling effect.
Patent AU-2022230441-A1 (AU)
Title: Fasl expression and fasr gene knockout to protect therapeutic cells from allogeneic rejection and activation-induced cell death
Inventor: BETHUNE MICHAEL THOMAS
IPC: C07K14/725
Filed: 2022-03-04
Abstract: Compositions, methods, expression vectors and engineered immune cells for improving therapies that entail the administration of allogeneic cells to a patient. An immune cell, e.g., a T cell, modified to comprise and/or express FasL protein or a FasL protein derivative from, for example, an expression vector comprising a polynucleotide that encodes FasL protein or a FasL protein derivative, and to express FasR at a reduced level, and further modified to comprise and/or express an antigen binding protein e.g., a chimeric antigen receptor (CAR). An improved method of CAR T-cell therapy that comprises administering the improved immune cells, and compositions that comprise the improved immune cells. Methods of improving persistence of administered cells and reducing activation-induced cell death comprising administering the improved cells.
Patent AU-2022232007-A1 (AU)
Title: Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody
Inventor: HSIA ELIZABETH C
IPC: C07K16/24
Filed: 2022-03-10
Abstract: A method of treating psoriatic arthritis in a patient having showed an inadequate response to treatment with an anti-TNF therapy by administering an IL-23 specific antibody, e.g., guselkumab, in a clinically proven safe and clinically proven effective amount and the patient achieves significant ACR20/50/70, IGA, HAQ-DI, CRP, SF-36 PCS/MCS, MDA, VLDA, enthesitis, dactylitis, and LEI/dactylitis improvement as measured 16, 24 and 48 weeks after initial treatment.
Patent AU-2022241560-A1 (AU)
Title: Systems and methods for patient-enabled bladder control
Inventor: IMRAN MIR
IPC: A61N1/00
Filed: 2022-09-29
Abstract: A system for controlling urination in a patient includes an implantable controller and an external 
device. The implantable controller includes circuitry and electrodes for stimulating the pudenal 
nerves in order to control urination. In addition, the implantable controller includes sensors for 
determining information on bladder fullness and for transmitting such information to an external 
device which is used for controlling the implanted controller. The external device will display 
when bladder filling exceeds a safe threshold level, allowing the patient and a caregiver to take 
appropriate steps to allow the patient to urinate.  
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Patent AU-2022241774-A1 (AU)
Title: Diterpenoid compounds that act on protein kinase c (pkc)
Inventor: CHEN RUIHONG
IPC: A61K36/14
Filed: 2022-03-23
Abstract: This present disclosure relates to a method of stimulating an immune response using compounds that activate protein kinase C (PKC), including for treatment of a cancer, a precancerous lesion, a benign tumor, or a wound.
Patent AU-2022242055-A1 (AU)
Title: Use of albumin for the treatment of defective b-cell function
Inventor: ARROYO PEREZ VICENTE
IPC: A61K38/38
Filed: 2022-03-25
Abstract: The present invention relates to a composition comprising human albumin for regulating B-cell function in a patient suffering from systemic inflammatory response syndrome, in which the albumin is administered to the patient in a dose sufficient to increase B-cell receptor density in a B-cell population.
Patent AU-2022246162-A1 (AU)
Title: Viral vectors with reduced immunogenicity
Inventor: JIANG SHAOYI
IPC: C12N15/86
Filed: 2022-03-25
Abstract: Compositions and methods for modified viral vectors which mitigate the immunogenicity of viral vectors, enabling multiple administrations of viral-based gene delivery viral vectors are described herein. The viral vectors advantageously possess low immunogenicity and comprise at least one immunosuppressive moiety. Also described herein are methods for introducing genetic material into a cell. Additionally, described herein are methods for preparing a modified viral vector. Lastly, described herein are methods for treating a subject, the method comprising administering to a subject a modified viral vector composition as described above.
Patent AU-2022258316-A1 (AU)
Title: Pyrolysis of plastic waste to produce light gaseous hydrocarbons and integration with an ethylene cracker
Inventor: ABBOTT RONALD G
IPC: C10G1/10
Filed: 2022-04-12
Abstract: Processes for using pyrolysis gas as a feedstock or a co-feedstock for making a variety of chemicals, for example, circular ethylene, circular ethylene polymers and copolymers, and other circular products. In these processes, pyrolysis reactor conditions can be selected to increase or optimized the production of pyrolysis gas over pyrolysis oil, and the pyrolysis gas which is usually used as fuel or flared can be fed downstream of the steam cracker furnace for economic use to form circular chemicals. Operating parameters of the pyrolysis unit may be adjusted to increase or decrease the proportion of pyrolysis gas relative to pyrolysis liquid as a function of their relative economic values.
Patent AU-2022266595-A1 (AU)
Title: Systems and methods for automatic carbon intensity calculation and tracking
Inventor: GRUBER PATRICK
IPC: G06Q10/06
Filed: 2022-04-26
Abstract: Examples of the present disclosure describe systems/methods for automatically generating and tracking a carbon intensity (CI) score assigned to a particular product as the product traverses through a processing plant and discrete steps in a supply chain. In some examples, intermediate CI scores may be assigned to the product as it completes each step in its life cycle. The intermediate CI scores may be aggregated to produce a final CI score. Each intermediate CI score is recorded on a blockchain, such that the CI score is independently verifiable and auditable. In other example aspects, a machine-learning model may be applied to the input data received from each supply chain stakeholder and CI scores, wherein the machine-learning model generates intelligent suggestions to stakeholders for how to tweak their processes to lower CI scores. In other examples, a CI score may be used to derive a value for a CI token.
Patent AU-2022282461-A1 (AU)
Title: Tissue container systems
Inventor: KOEPSEL JUSTIN
IPC: A61L27/60
Filed: 2022-05-27
Abstract: The present disclosure relates generally to tissue container systems and kits that find use in the transport of tissues and methods of using the tissue container systems. In particular, systems and kits that support the transport, thawing and use of cryopreserved human skin equivalents, and methods of their use by a health care provider are provided.
Patent AU-2022288632-A1 (AU)
Title: Respiration sensing
Inventor: THORP CHRISTOPHER
IPC: A61B5/113
Filed: 2022-06-09
Abstract: A device includes a sensor and a control portion. The sensor is securable to a patient to provide a sensor signal. The sensor is to sense changes in acceleration indicative of respiration of the patient. The control portion is to determine a midpoint of each respiratory phase of the patient based on the sensor signal.
Patent AU-2022294335-A1 (AU)
Title: Redox flow battery system
Inventor: KIYABU TOSHIYASU
IPC: H01M8/18
Filed: 2022-02-14
Abstract: Provided is a redox flow battery system wherein operations relating to charging and discharging of a redox flow battery have been improved. This redox flow battery system comprises a redox flow battery and a power supply device that supplies power for charging the redox flow battery to the redox flow battery, wherein the power supply device reduces the power supplied to the redox flow battery as charging of the redox flow battery approaches completion.
Patent AU-2022329894-A1 (AU)
Title: Process for purifying and producing a high purity particulate graphite material for use in lithium-ion batteries
Inventor: WATSON KEVIN
IPC: C01B32/215
Filed: 2022-08-18
Abstract: A process for purifying and producing coated high purity particulate graphite materials suitable for use in lithium-ion batteries (LiBs) is described herein. More specifically, the process comprises agglomerating a graphite feed or treating a graphite feed with an agglomerating agent to produce an agglomerated particulate graphite feed; and reacting the agglomerated particulate graphite feed in the presence of a chlorine-containing gas to produce a mixture comprising a purified agglomerated particulate graphite material and a chlorine-containing gas laden with chlorinated impurities. The process may further comprise an alkaline leaching step. A coated particulate graphite material comprising a purity in excess of 99.95 wt.% C. and its use as anode material in rechargeable LiBs is also disclosed.
Patent WO-2023178378-A1 (WO)
Inventor: HOLZGRABE ULRIKE
IPC: C07D401/12
Filed: 2023-03-21
Abstract: La présente invention concerne d'une manière générale des composés dérivés d'acide pipécolique, en particulier des composés dérivés d'acide pipécolique de formule (I), et des formulations et des compositions les comprenant. La présente invention concerne également des procédés et des utilisations de ces composés, compositions et/ou formulations dans le traitement et/ou la prévention d'une maladie ou d'un état à médiation par un pathogène qui est sensible à l'inhibition de protéines de potentialisateur d'infectivité des macrophages (Mip), et/ou d'une maladie ou d'un état à médiation dans lequel la protéine Mip est un facteur de virulence.
Patent WO-2011097692-A1 (WO)
Title: Método de produção de látex livre de emulsificantes via polimerização em emulsão e produto resultante
Inventor: MARIM DE OLIVEIRA ADRIANO
IPC: C08F2/32
Filed: 2011-01-28
Abstract: A presente invenção método de produção de látex livre de emulsificantes via polimerização em emulsão e produto resultante apresenta um método de obtenção de dispesrões poliméricas por meio da técnica de polimerização em emulsão sem a necessidade do uso de emulsificantes ou colóides protetores. Neste método, o uso de particulas sólidas coloidais e alguns monômeros específicos possibilitam a emulsificação dos monômeros lipossolúveis em meio aquoso e a obtenção de dispersões poliméricas em escala nanométrica com excelentes estabilidade coloidal. O método de preparação das emulsões é baseado na polimerização de monôméros etilênicos insaturados, hidrofóbicos e lipossolúveis em meio aquoso na presença de um óxido coloidal, como sílica, titânia ou óxido de zinco, permitindo a preparação de emulsões com tamanho de particulas muito diferentes, variando de 50nm até 10 µm.
Patent WO-2021007638-A1 (WO)
Inventor: ZANGIROLAMI AMANDA CRISTINA
IPC: A61K31/12
Filed: 2020-07-15
Abstract: The present invention describes methods for obtaining functionalized polymeric surfaces (MPn-PSm) from polymers or copolymers with appropriate functionalizations (X), which can be a halogen or a leaving group, such as polyvinyl chloride (MP1) and (Chloromethyl)polystyrene-Merrifield (MP2), and curcumin photosensitizers (PS1),  meso -Tetra(aryl)porphyrins, halogenated and functionalized chlorins and bacteriochlorins with nucleophilic groups (PS2). The structures of all of the photosensitizers in the present application incorporate the functional group (Y), which is an OH, SH or NH 2  nucleophile. The application also describes the covalent bonding process of the photosensitizers PS1-PS3 to the functionalized polymeric materials MP1-MP2 by means of a nucleophilic substitution reaction to prepare the MPn-PSm products. The formed products prevent microbial proliferation, which can cause the serious infections that are one of the main causes of death in patients using these devices.
Patent WO-2022213160-A1 (WO)
Inventor: DA SILVA PAULO ANCHIETA
IPC: A61L2/24
Filed: 2021-04-05
Abstract: L'invention concerne un système et un procédé de désinfection pour intérieurs d'aéronefs basés sur une commande de l'intensité et de l'irradiation d'ondes ultraviolettes, en particulier le rayonnement ultraviolet C lointain (FAR-UVC) dans la plage allant de 220 nm à 224 nm, de telle sorte que leur application ne pose pas de problèmes cliniques vis-à-vis des êtres humains, et destinés à être utilisés pendant les opérations de vol, ainsi que la préparation des aéronefs, le pré-embarquement et le débarquement.