Patent SG-11201809581R-A (SG)
Title: Method and product for caries treatment
Inventor: HUG MICHAEL
IPC: C07K7/00
Filed: 2017-05-24
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property :::` , Organization 03 11111111111101110101011111010111110 010101101011111101111101111111011110111111 International Bureau (10) International Publication Number (43) International Publication Date ......°' WO 2017/202943 Al 30 November 2017 (30.11.2017) WIPO I PCT (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, A61K 8/64 (2006.01) A61K 38/04 (2006.01) CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, A61Q 11/00 (2006.01) A61P 1/02 (2006.01) DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, A61K 6/00 (2006.01) A61C 17/00 (2006.01) HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, CO7K 7/00 (2006.01) KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, (21) International Application Number: MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PCT/EP2017/062593 PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, (22) International Filing Date: TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. 24 May 2017 (24.05.2017) (84) Designated States (unless otherwise indicated, for every (25) Filing Language: English kind of regional protection available): ARIPO (BW, GH, (26) Publication Language: English GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (30) Priority Data: TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, 16171027.2 24 May 2016 (24.05.2016) EP EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (71) Applicant: CREDENTIS AG [CH/CH]; Dorfstrasse 69, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, 5210 Windisch (CH). KM, ML, MR, NE, SN, TD, TG). (72) Inventors: HUG, Michael; Rigiweg 11, 4800 Zofmgen (CH). LYSEK, Dominikus Amadeus; Millligerstr. 16t, Published: 5210 Windisch (CH). — with international search report (Art. 21(3)) (74) Agent: MORE, Solveig; df-mp Dorries Frank-Molnia & — with sequence listing part of description (Rule 5.2(a)) = Pohlman, Patentanwalte Rechtsanwalte PartG mbB, Filnf = Wife, TheatinerstraBe 16, 80333 Munich (DE). = Designated States (unless otherwise indicated, for every = (81) kind of national protection available): AE, AG, AL, AM, (54) Title: METHOD AND PRODUCT FOR CARIES TREATMENT = (57) : The present invention provides new dental care = Fig. , products comprising self-assembling peptides (SAP) that are ca- = pable of undergoing self-assembly at a certain pH for use in den- = = .Format: Toothpaste/ Mouthwash Cemoval of biofilm on tooth surface tal care, e.g. preventing and/or treating a tooth lesion such as a caries lesion, remineralising a tooth surface, increasing smooth- = = TH: Acid ness or shine or increasing hardness of a tooth surface. The den- = D.,,,,g1,„ DIUIIIIII .Containv. Water, Ethanol, Glycerin, Flavour, CPC, Ma-Saccharine, Phosphoric Add or citric acid, Potassium sorbate, Poloxamer 407, disodium phosphate, fluoride tal care products may be administered following a simple proto- - I col involving multiple steps, e.g., comprising tooth brushing with = = a sonic tooth- brush such as an ultrasonic toothbrush and/or use = of an oral irrigator, thereby enabling non-targeted treatment of a .Format: solution TH: neutral-basic plurality of teeth in a subject, independent of the diagnosis of ac- tive caries, i.e., not previ- ously successfully treated caries. The = Pelllci e • .Contains Water, Glycerin, Flavour, ado Acid, Potassium sorbate„ Poloxamer 407, disodium phosphate, fluoride, Sodium Chloride, Di-Sodium hydrogen phsophate, Potassium dihydrogen phosphate, Sodium Lam' Sulfate, EDTA invention also relates to said method as well as kits and devices suitable therefor. = Il ) 29 43 A \" .Format: solution 'pH: slightly basic L esion c . ontains: PUP/ Glycercd, water, ethanol, sucrose, PlIATRIS I N IN —.._. 1-1 © N C