baber/WOPTO huggingface dataset:
Patent CA-3045650-A1 (CA)
Title: Compositions et methodes d'activation d'expression genique
Inventor: KAMRUD KURT IVER
IPC: C12N15/86
Filed: 2017-12-04
Abstract: La présente invention concerne de manière générale des molécules d'acide nucléique destinées à être utilisées pour réguler l'expression génique. L'invention concerne des molécules d'acide nucléique contenant un ou plusieurs éléments structuraux de l'activateur de capside virale liés fonctionnellement à une séquence de codage d'un gène d'intérêt. Dans certains modes de réalisation, l'activateur de capside virale comprend une boucle aval (DLP) provenant d'une protéine de capside virale, ou un variant de la DLP.
Patent CA-3047654-A1 (CA)
Inventor: YU BIN
IPC: H04L9/32
Filed: 2019-06-21
Abstract: Il est décrit une méthode de mise en uvre du VXLAN, un appareil réseau et un système de communication servant à réduire les coûts de mise en uvre globaux dun VXLAN dans un réseau de campus. La méthode en question comprend les étapes suivantes : obtenir, au moyen dun appareil réseau, une mise en correspondance entre un identifiant de réseau local dentreprise virtuel (VLAN) et un identifiant de réseau VXLAN; recevoir, par lintermédiaire dun port de lappareil réseau, une trame Ethernet acheminée par un dispositif daccès, dans laquelle un champ étiquette de VLAN dans la trame Ethernet comprend lidentifiant de VLAN; ajouter, au moyen de lappareil réseau, un en-tête de VXLAN à la trame Ethernet fondé sur lidentifiant VLAN et sur la mise en correspondance en vue dobtenir un paquet de VXLAN, dans lequel un champ didentifiant de réseau VXLAN dans len-tête de VXLAN comprend lidentifiant de VNI; envoyer, au moyen de lappareil réseau, le paquet de VXLAN.
Patent CA-3047681-A1 (CA)
Title: Method for determining a validity of an application code, corresponding device and computer program product
Inventor: ROLIN CHRISTIAN
IPC: G06F8/72
Filed: 2019-06-20
Abstract: The proposed technique relates to a method for determining a validity of a code of an application (App), said method being implemented within an electronic device comprising a processor, a non-secure memory and a secure memory, said method being characterized in that it comprises at least one iteration of the following steps: - a step for loading (11) said application in said non-secure memory, delivering a current application code (CAC); - a step for determining (12) a footprint of said current application code, delivering a current footprint (Emp_C) associated with the application; - a step for obtaining (13), within said secure memory, a reference footprint (Emp_Rf) associated with the application; - a step for comparing (14) said current footprint (Emp_C) with said reference footprint (Emp_Rf); and - when said current footprint (Emp_C) is identical to said reference footprint (Emp_RO, a step for validating (15) said current application code, comprising: - a step for executing an optimization process (151) of the current application code of said application, delivering an optimized application code (CA0); - a step for determining (152) a footprint of said optimized application code (CAO), delivering a post-optimization footprint (EMP_PO) associated with said application; - a step for recording (153) said post-optimization footprint (Emp_PO) in said secure memory as a new reference footprint associated with said application.
Patent CA-3052029-A1 (CA)
Inventor: HENNION ALEXANDRE
IPC: B32B17/10
Filed: 2018-02-01
Abstract: The invention relates to laminated glass (10) comprising a first glass sheet (1) and a second glass sheet (3) bonded to one another by means of an adhesive interlayer (2), said second glass sheet (3) having a through-hole (4). The laminated glass is characterised in that a thin sheet (5) is inserted between the adhesive interlayer (2) and the second glass sheet (3) on the surface of the hole (4) and on the peripheral surface surrounding same (4), said thin sheet having a thickness of between 0.01 and 0.5 mm and being made from a material compatible with the production of the laminated glass (10) and the mechanical stress and ageing of same. The invention also relates to the method for producing the laminated glass and to the use of said glass for the incorporation of an element that is optionally connected to a power supply.
Patent CA-3056572-A1 (CA)
Inventor: TSUBOI HIDEKAZU
IPC: H04W16/32
Filed: 2018-03-20
Abstract: This terminal device: receives a first measurement setting from a first base station device via a first SRB; receives a second measurement setting from a second base station device via a second SRB; sends, via the first SRB, a first measurement result in response to the first measurement setting that has been set from the first base station device via the first SRB; and sends, via the second SRB, a second measurement result in response to the second measurement setting that has been set from the second base station device via the second SRB.
Patent CA-3061064-A1 (CA)
Inventor: STRIMPEL JASON
IPC: G06F8/60
Filed: 2019-11-07
Abstract: A computing system may include a computing device configured to build modules of script code into bundles, and a bundler application executable to perform operations comprising:  obtaining one or more of the modules of script code that are designated for bundling with one another; organizing the modules of script code into one or more chunks; for each respective chunk of the one or more chunks: (i) determining whether the respective chunk is to be assigned a deterministic chunk identifier or a non-deterministic chunk identifier, and (ii) assigning the respective chunk a chunk identifier as determined, where deterministic chunk identifiers are usable for referencing by additional modules of script code both within and not within in the respective chunk, and where the deterministic chunk identifiers are independent of characteristics of the computing device; and writing the one or more chunks to a bundle.
Patent CA-3062847-A1 (CA)
Inventor: WITTENBERG WILLIAM
IPC: B65D25/20
Filed: 2019-11-27
Abstract: A product display package includes a product tray configured to hold one or more products. The product tray includes a bottom wall connected to a front wall, to a back wall, to a left side wall, and to a right side wall to form an interior chamber, and a display opening in the product tray provides physical access to the interior chamber such that one or more products may be placed into or removed through the display opening. The product display package includes a barrier label adhered to the product tray such that it overlies the display opening. The barrier label includes a center panel that substantially closes the display opening and forms a physical barrier to restrict physical access to a product in the interior chamber of the product tray.
Patent CA-3064461-A1 (CA)
Title: Vaccine against necrotic enteritis in poultry
Inventor: GONG JIANHUA
IPC: A61P37/04
Filed: 2018-05-31
Abstract: An immunogenic polypeptide selected from an isolated Clostridium perfringens pilus polypeptide, a variant of the pilus polypeptide; a fragment of the pilus polypeptide; and a fragment of the variant, is useful for the preparation of a vaccine for the treatment or prevention of enteric necrosis in poultry. The isolated Clostridium perfringens pilus polypeptide includes an assembled pilus or the pilus subunits CnaA, FimA and/or FimB.
Patent CA-3065035-A1 (CA)
Title: Cap hub interface for intradermal injection device
Inventor: ZUCCHELLI JEREMY
IPC: A61M5/34
Filed: 2018-06-01
Abstract: An injection device including a syringe comprising a barrel having a distal end and a proximal end and a tip provided on the distal end of the barrel, the barrel defining an internal bore extending from the proximal end to the distal end of the barrel; a luer lock adaptor comprising a body having a proximal end and a distal end, a reduced-diameter portion provided on the proximal end of the body, and a threading provided on an outer surface of the body, the reduced-diameter portion defining an opening to receive the tip of the syringe in a friction fit; and a needle hub comprising a body defining an inner cavity, a needle receiving portion extending distally from the body, and a skirt extending inwardly into the inner cavity, wherein an inner surface of the body includes a threading corresponding to the threading of the luer lock adaptor to connect the luer lock adaptor to the needle hub, wherein the needle receiving portion defines a bore to receive the tip of the syringe.
Patent CA-3067501-A1 (CA)
Title: Binding machine
Inventor: NAGAOKA TAKAHIRO
IPC: E04G21/12
Filed: 2016-07-21
Abstract: It provides a reinforcing bar binding machine capable of reliably performing a gripping operation of a wire with a simple configuration. The reinforcing bar binding machine includes: a first movable gripping member (70L) that is displaced in a direction coming in contact with and separating from one side of a fixed gripping member (70C); a second movable gripping member (70R) that is displaced in a direction coming in contact with and separating from the other side of the fixed gripping member (70C); a bending portion (71) that brings the first movable gripping member (70L) and the second movable gripping member (70R) into and out of contact with the fixed gripping member (70C), wherein the fixed gripping member (70C) includes a shaft (77) that rotatably supports the first movable gripping member (70L) and the second movable gripping member (70R), and the bending portion (71) includes an opening and closing pin (71a) that pushes an opening and closing guide hole (77L) provided in the first movable gripping member (70L) and an opening and closing guide hole (77R) provided in the second movable gripping member (70R).
Patent CA-3068841-A1 (CA)
Inventor: JONES DOUGLAS S
IPC: A61K38/20
Filed: 2018-07-03
Abstract: Les protéines de fusion qui comprennent un fragment de ciblage immunitaire (par exemple ., Treg) une molécule de cytokine ou de facteur de croissance, des produits pharmaceutiques et des formulations de ceux-ci, et des procédés d'utilisation et de fabrication de ceux-ci.
Patent CA-3069073-A1 (CA)
Inventor: FAST JONAS
IPC: C07K16/28
Filed: 2018-07-26
Abstract: This invention relates to a pharmaceutical formulation of a bispecific antibody which binds to carcinoembryonic antigen (CEA) and CD3, a process for the preparation and uses of the formulation.
Patent CA-3074571-A1 (CA)
Inventor: CLAYTON MATT
IPC: A61G13/04
Filed: 2018-08-31
Abstract: A surgical table comprising: a base for standing on a floor; a column mounted on and extending from the base; a tabletop providing a patient support surface; a movable framework to which at least a part of the tabletop is directly or indirectly fitted, and a rack and pinion mechanism fitted to the movable framework between the tabletop and the column for enabling the movable framework, and the part of the tabletop fitted thereto, to be rotated about a pivot axis, wherein the pivot axis is a trend axis extending in a transverse direction across the tabletop or a tilt axis extending in a longitudinal direction along the tabletop, wherein the rack and pinion mechanism comprises: a pair of opposed first and second curved racks mounted on opposite sides of the pivot axis, the racks facing inwardly towards the pivot axis and being oriented upwardly, a pair of first and second rotatable pinions, each first and second pinion arranged to engage a respective first and second curved rack, and a drive system, including a drive motor, connected to the pinions for rotating the first and second pinions in a common rotational direction, the drive system being configured so that the first and second pinions move in opposite respective upward or downward directions along the respective first and second curved racks to rotate the movable framework about the pivot axis.
Patent CA-3075003-A1 (CA)
Title: Trepanning tool with plug management
Inventor: PORTER ROBIN
IPC: B23B51/04
Filed: 2020-03-10
Abstract: A trepanning apparatus, including a shaft portion extending along a longitudinal axis; an annular cutter portion; and a connecting portion extending axially between the shaft portion and the cutter portion, the connecting portion including a pair of arms each having a front end connected to the cutter portion and a rear end connected to the shaft portion, the arms circumferentially spaced from one another about the longitudinal axis to provide diametrically opposed first and second openings, a first plug retaining surface defined by a first portion of the rearward end of the cutter portion having a first circumferential extent bounded by the front ends of the arms, and a second plug retaining surface defined by a second portion of the rearward end of the cutter portion having a second circumferential extent bounded by the front ends of the arms, the first circumferential extent greater than the second circumferential extent.
Patent CA-3075215-A1 (CA)
Title: Inhibiteur de l'histone desacetylase en association avec un modulateur de point de controle immunitaire pour la cancerotherapie
Inventor: DANHAUSER-RIEDL SUSANNE
IPC: A61P35/00
Filed: 2018-09-07
Abstract: L'invention concerne des méthodes, des compositions et des utilisations pour le traitement du cancer consistant à administrer un inhibiteur de l'histone désacétylase (HDAC) tel que défini dans la description pour le traitement du cancer en association avec au moins un modulateur de point de contrôle immunitaire tel que défini dans la description.
Patent CA-3079434-A1 (CA)
Title: Lid holder
Inventor: GROLL WILLIAM A
IPC: A47J47/10
Filed: 2018-10-17
Abstract: A lid holder has a base portion and a pair of spaced apart arms having a proximal end connected to the base portion and a free distal end extending away from the base portion. The lid holder further has a U-shaped lug at the free distal end of each arm, the lug having a first end and a second end directed toward the base portion, and a leg connected to the second end of each U-shaped lug. The arms are deflectable from a first position to a second position with application of a deflecting force such that at least a portion of the arms is insertable between vertically extending posts of a lid handle. After a deflecting force is removed, the arms revert back toward the first position, thereby engaging the legs with the vertically extending posts of the lid handle.
Patent CA-3080507-A1 (CA)
Title: Hands free door opener
Inventor: PEARSON DANIEL P
IPC: E05F11/54
Filed: 2020-05-08
Abstract: A hands-free door opener is provided, including a housing body affixable to a lower end of a face of a door; and a contact component rotationally housed within the housing body, the contact component providing a contact surface for engagement with, and rotation by a foot. Rotation of the contact component by a foot serves to impart lateral movement to the door opener to thereby open the door. A method is further provided for hands free opening of a door. The method includes the steps of engaging with a foot, a contact surface of a door opener affixed to a door and rotating the foot in a first direction to cause rotation of the contact surface of the door opener and rotation of the door about its hinges in a second direction to open said door.
Patent CA-3082187-A1 (CA)
Title: System and method for collaborative and interactive image processing
Inventor: LE NAOUR GILLES
IPC: G06T11/60
Filed: 2018-12-07
Abstract: The invention proposes a system (100) and a method for collaborative and interactive image processing aiming to limit errors in the examination of an image. The system according to the invention comprises a distribution console (110) for distributing images to be processed (200) and for collecting annotated images capable of communicating locally with at least two processing interfaces (120) capable of displaying an image to be processed. The console and the interfaces are programmed to transmit a copy of the image to be processed to each processing interface from the distribution console, to provide tools for modifying the copy of the image on each interface so as to obtain an annotated image, to transmit each annotated image to the distribution console from each processing interface, and to generate a resulting image from the annotated images using a determined combinatorial algorithm representing the common points and the differences between the annotated images.
Patent CA-3082204-A1 (CA)
Inventor: LEE JOHN
IPC: C07K14/725
Filed: 2018-12-11
Abstract: The present invention pertains to engineered immortalized T-cell lines, method for their preparation and their use as medicament, particularly for immunotherapy.  The engineered immortalized T-cell lines of the invention are characterized in that the expression of endogenous T-cell receptors (TCRs) and beta 2-microglobulin (B2M) is inhibited, e.g., by using an endonuclease able to selectively inactivate the TCR and B2M genes in order to render the immortalized T-cells non-alloreactive.  In addition, expression of immunosuppressive polypeptide can be performed on those engineered immortalized T-cells in order to prolong the survival of these T-cells in host organisms. Such engineered immortalized T-cells are particularly suitable for allogeneic transplantations, especially because it reduces both the risk of rejection by the hosts immune system and the risk of developing graft versus host disease. The invention opens the way to standard and affordable adoptive immunotherapy strategies using immortalized T-cells for treating cancer, infections and auto-immune diseases.
Patent CA-3082654-A1 (CA)
Inventor: CHENG MANQUN
IPC: A44B11/00
Filed: 2020-06-05
Abstract: A magnetic buckle assembly includes a first buckle component, a second buckle component, a switch, an operating component, a first magnetic component, a second magnetic component and a latch. The switch is movably disposed on the second buckle component. The operating component is linked to the switch. The first magnetic component is disposed on the first buckle component. The second magnetic component is disposed on the switch. The latch is movably disposed on the second buckle component and for engaging with the first buckle component to prevent separation of the first buckle component and the second buckle component. The operating component drives the switch to move to change a direction of a magnetic force of the second magnetic component acting on the first magnetic component when the operating component is operated to disengage the latch from the first buckle component.
Patent CA-3085105-A1 (CA)
Title: Unit of a coffee apparatus having a bean container, a portioning device and a grinder
Inventor: DEUBER LOUIS
IPC: A47J42/08
Filed: 2018-12-21
Abstract: The invention relates to a unit of a coffee apparatus, in particular a coffee machine for brewing a coffee drink, having a coffee bean container (1) for storing the coffee beans, a portioner (2) for portioning the coffee beans for an individual portion, and a grinder (4) for grinding the portioned coffee beans. The coffee bean container (1) and the portioner (2) are formed in a common container module. The unit has a module receptacle (3), by means of which the container module can be connected during use and removed after use, and the container module has settings for a portion amount and a degree of grinding, which can be selected by the user, wherein the portion amount setting influences the portioner (2) and the degree of grinding setting influences the grinder (4). A simple, cost-effective and easy-to-use information exchange module between coffee container and coffee apparatus is thereby created.
Patent CA-3086514-A1 (CA)
Title: Monitoring system for securing networks from hacker drones
Inventor: CORRENTI MATTHEW DANIEL
IPC: H04W12/00
Filed: 2018-12-21
Abstract: Methods, systems, and apparatus, including computer programs encoded on a storage device, for securing a network associated with a property in response to the detection of a hacking drone within a vicinity of the property. In one aspect, a method includes obtaining sensor data from one or more sensors located at a property, detecting, based on the obtained sensor data, the presence of a drone, determining, based on the obtained sensor data, that the detected drone is an unauthorized drone, determining, by the monitoring system, that the unauthorized drone (i) is communicating or (ii) attempting to communicate with a network associated with the property, selecting one or more network adjustment policies, and transmitting one or more instructions to (i) one or more monitoring system components or (ii) one or more network components that are configured to adjust network parameters based on the one or more selected network adjustment policies.
Patent CA-3088200-A1 (CA)
Inventor: BANNEN LYNNE CANNE
IPC: C07D215/22
Filed: 2019-01-25
Abstract: Disclosed herein are compounds of formula I. Compounds of formula I inhibit, regulate and/or modulate kinase receptor, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.
Patent CA-3088355-A1 (CA)
Inventor: OSBORNE AARON
IPC: A61P27/02
Filed: 2019-02-05
Abstract: The current invention relates to the use of antibodies which bind to VEGF and ANG2 for the treatment of ophthalmologic diseases.
Patent CA-3093499-A1 (CA)
Title: Composes et leurs utilisations pour traiter des tumeurs chez un sujet
Inventor: ZIMMERMANN ASTRID
IPC: A61K45/06
Filed: 2019-03-13
Abstract: La présente invention concerne des composés qui peuvent être utilisés pour induire la mort cellulaire immunogène (ICD). Dans certains cas, au moins deux composés sont combinés pour induire une ICD. L'invention concerne également la combinaison de composés induisant l'ICD avec un agent stimulant le système immunitaire, tel qu'un inhibiteur de point de contrôle immunitaire, en particulier, pour traiter le cancer ou inhiber la croissance tumorale.
Patent CA-3093648-A1 (CA)
Inventor: YOSHIMURA TOMOKI
IPC: H04W28/04
Filed: 2019-03-12
Abstract: L'invention concerne un dispositif terminal qui comprend : une unité de réception qui reçoit un PDCCH, et reçoit un PDSCH à planifier par le PDCCH ; et une unité de transmission qui transmet, à l'aide d'un PUCCH, un ou plusieurs HARQ-ACK comprenant au moins un HARQ-ACK correspondant à un bloc de transport inclus dans le PDSCH, et une SR. Si le nombre de bits de l'HARQ-ACK est deux ou moins, une ressource pour le PUCCH est donnée d'une ou plusieurs ressources PUCCH incluses dans certains ensembles de ressources PUCCH sur la base d'au moins une première valeur, la première valeur est donnée sur la base d'au moins le nombre de bits du ou des HARQ-ACK transmis tout en étant inclus dans le PUCCH, quel que soit le nombre de ressources pour la SR qui entrent en collision avec le PUCCH, et si le nombre de bits du HARQ-ACK dépasse deux, la ressource pour le PUCCH étant donnée de la ou les ressources PUCCH incluses dans l'ensemble de ressources PUCCH sur la base d'au moins la somme du nombre de bits du ou des HARQ-ACK et du nombre de bits de la SR.
Patent CA-3094816-A1 (CA)
Inventor: GARCIA-BLANCO MARIANO A
IPC: C07H21/04
Filed: 2019-03-22
Abstract: The present invention includes compositions and methods for treating an autoimmune disorder or a cancer in a subject in need thereof, the method comprising: administering an effective amount of a composition comprising an oligonucleotide that specifically binds a complementary sequence of the Interleukin-7 receptor (IL7R) pre-mRNA that influences splicing of exon 6, wherein the SM-ASO increases or decreases inclusion of exon 6 in IL7R pre-mRNAs and respectively decreases or increases expression of the soluble isoform of IL7R (sIL7R). In certain embodiments, the oligonucleotide is an antisense oligonucleotide (ASO), or a splice- modulating antisense oligonucleotide (SM-ASO).