Patent SG-11201807185U-A (SG)
Title: Modified hyaluronic acid, method for making same and uses thereof
Inventor: KRAUS ANDREAS
IPC: C08L5/08
Filed: 2017-03-21
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 1111111101111011101010111110101111101110111110101111111111101111101111011111 International Bureau 0.. .... .. (10) International Publication Number (43) International Publication Date ..... ..or::,„, WO 2017/162676 Al 28 September 2017 (28.09.2017) WIP0 I PCT (51) International Patent Classification: NERSCHAFT MBB; Dr. Erich Fritsche, Zweibrftcken- C08B 37/08 (2006.01) CO8J 3/075 (2006.01) strasse 5-7, 80331 Munich (DE). A61K 47/36 (2006.01) A61L 27/20 (2006.01) A61K 31/728 (2006.01) A61L 27/52 (2006.01) (81) Designated States (unless otherwise indicated, for every CO8L 5/08 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: PCT/EP2017/056701 BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (22) International Filing Date: 21 March 2017 (21.03.2017) KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (25) Filing Language: English NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (26) Publication Language: English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (30) Priority Data: ZA, ZM, ZW. 16000715.9 24 March 2016 (24.03.2016) EP (84) Designated States (unless otherwise indicated, for every (71) Applicant: MERZ PHARMA GMBH & CO. KGAA [DE/DE]; Eckenheimer Landstrasse 100, 60318 Frankfurt am Main (DE). kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (72) Inventors: KRAUS, Andreas; Peter-Vischer-StraBe 18, 91126 Schwabach (DE). LINKO, Alexander; Nieder- urseler Landstrasse 24, 60438 Frankfurt am Main (DE). VILLAIN, Franck; 61, rue de Bagnolet, 75020 Paris DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (FR). Published: Agent: WALLINGER RICKER SCHLOTTER TOST- (74) - with international search report (Art. 21(3)) MANN PATENT- UND RECHTSANWALTE, PART- 1-1 IN ei 1-1 (54) Title: MODIFIED HYALURONIC ACID, METHOD FOR MAKING SAME AND USES THEREOF C 1-1 (57) : The present invention generally relates to a modified hyaluronic acid (HA) and to a method for making same, more ei specifically to a (poly)glycerol-modified HA derivative prepared by grafting glycidol to HA. The present invention also relates to the en. ) use of the HA derivative for preparing a dermal filler composition, a hydrogel comprising cross-linked HA and the (poly)glycer- ol-modified HA derivative, and a method for preparing said hydrogel. Furthermore, the present invention relates to the use of the hy- drogel as a cosmetic and/or aesthetic product, in particular as a dermal filler for tissue filling, replacing and/or augmenting.