baber/WOPTO huggingface dataset:
Patent YU-25000-A (YU)
Title: Indazole bioisostere replacement of catechol in therapeutically active compounds
Inventor: MARFAT ANTHONY
IPC: A61P9/02
Filed: 1998-10-26
Abstract: Therapeutically active compositions of matter and member species thereof are described which comprise indazole-containing compounds, said compounds and their therapeutic activity resulting directly from an indazole-for-catechol bioisostere replacement of a catechol-containing compound having the same therapeutic activity, where non-catechol substituents are the same or homologous before and after said replacement, and wherein said compositions of matter comprise a compound of Formula (I1) or (I2), or a pharmaceutically acceptable salt thereof, wherein in a preferred embodiment RC is hydrogen; RA is cyclohexyl; and RB is ethyl. Ra and Rb are each individually and independently hydrogen or non-catechol substituents of said compounds resulting directly from an indazole-for-catechol bioisotere replacement of said catechol-containing compound having said therapeutic activity, where said non-catechol substituents are the same or homologous before and after said replacement, provided that both of Ra and Rb cannot be hydrogen at the same time. The therapeutic activity involved may comprise cholinesterase inhibitory activity, adrenergic α1-antagonist and ß1-agonist activity, calcium channel inhibitory activity, antineoplastic activity, and phosphodiesterase type IV inhibitor activity.
Patent YU-35192-A (YU)
Title: Poluprovodnički toplotni fluksmetar
Inventor: CVETKOVIC M
Filed: 1992-04-03
Abstract: POLUPROVODNIČKI TOPLOTNI FLUKSMETAR, u obliku čipa (2) se toplotno kompenzuje pomoću čipa (3), koji su čipovi (2 i 3) poluprovodnički termoparovi, koristeći za grejanje ili hladjenje čipa (3) Peltijeov (Peltier) efekat radi merenja toplotnog fluksa kroz pregradu (1), ima za novost to, da se čipom (3) podešava temperatura površine elektroizolacionog sloja (7) koja naleže na površinu pregrade (1) na temperaturu površine pregrade (1), pri čemu se toplotni fluks kroz pregradu (1) meri čipom (2), a slojevi (7) medjusobno električno izoluju pregradu (1) i čipove (2) i (3) i da su čipovi (2), (3) i slojevi (7) termički izolovani od spoljnjeg vazduha slojevima (4).
Patent YU-77190-A (YU)
Title: Nitrogen splitting copolymers, hybride copolymers of those splitting copolymers with random nitrogen copolymers and processes for preparing thereof
Inventor: BOLLINGER JOSEPH MARTIN
IPC: C10M149/10
Filed: 1990-04-18
Abstract: Hybrid copolymers of a nitrogenous grafted copolymer with a nitrogenous random polymer, and methods for their preparation, are provided. The hybrid copolymers can be prepared by first forming the nitrogenous graft copolymer and then copolymerizing additional constituent vinyl monomer(s) with residual nitrogenous monomer(s) to form the hybrid copolymer.
Patent BE-808729-A (BE)
Title: Hypolipaemic and catatoxic steroids - 16-aphacia-cyano-pregn-5-ene-3-beta-ol-20-one 3-esters and ethers
Inventor: ROOKS W H
IPC: A61K/
Filed: 1973-12-17
Abstract: Title cpds. of formula (I): (where R=H, 1-6C alkyl, 3-6C cycloalkyl, 2-7C acyl, tetrahydrofuran-2'-yl, tetrahydropyran-2'-yl, or 4'-(1-6C alkoxy)-tetrahydropyran-4'-yl). The cpds. (I; R=3-6C cycloalkyl) are novel, and are prepd. by condensing (I; R=H) with a cycloalkyl halide. Cpds. (I) assist the destruction of toxins by the liver, protect liver tissue, and facilitate the repair of damaged liver tissue.
Patent BE-898072-A (BE)
Title: Derives du pyrrole et leur preparation.
IPC: A61P25/02
Filed: 1983-10-25
Abstract: L'invention concerne des dérivés de benzodioxino-pyrroles. Les composés répondent à la formule (I), où R est H, alkyle en C1-C6 (à substitution cycloalkylique en C3-C7 éventuelle), alcényle ou alcynyle en C3-C6, cycloalkyle en C3-C7, aralkyle ou -CHO. Ils se préparent par l'amination de composés de la formule II, où X est un substituant labile, comme un halogène ou un groupe hydrocarbylsulfonyloxy. Ces composés sont des antagonistes de récepteurs alpha 2 adrénergiques sélectifs.
Patent BE-898769-A (BE)
Title: Solar heating installation for buildings - uses plate covered by transparent membrane as air heater and fan to circulate this air through building
IPC: F24J2/04
Filed: 1984-01-27
Abstract: The solar heating installation uses a generator formed from a heating plate covered with a transparent membrane under which passing air is heated by the solar radiation. The generator is fabricated with rounded corners to avoid sharp corners and pockets where air can stagnate and cool, and facilitating the upward motion of heated air towards the outlet. A vibrator is fitted to shake snow off the membrane. - A regulator is fitted, composed of thermostat operating a fan which draws hot air from the generator and directs it into the interior of the building, with air ingress being controlled by the user. A signal device indicates when the air is sufficiently heated to be admitted to the room, and excess heat is stored as latent heat in a chemical which melts, then solidifies when heat is withdrawn.(0/1)
Patent BE-898914-A (BE)
Title: Flexible bellows for tank breather pipe - has dessicant filter to prevent moisture and dust ingress
IPC: B65D90/34
Filed: 1984-02-15
Abstract: Hydraulic fluid tanks are fitted with breather pipes which are necessary to allow for normal changes of fluid volume during system operation and temperature variations. The flexible bellows may be circular or square in cross section and has a container filled with dessicant at the outlet to atmosphere. - The bellows is connected to the breather pipe of the tank via a tube with support brackets. It is fitted when the volume of oil in the tank is at a minimum, and the volume of the bellows expands and contracts accordingly thereafter.(0/1)
Patent CA-1049041-A (CA)
Inventor: VAN DE MOESDIJK CORNELIS G M
IPC: C07C27/00
Filed: 1973-11-19
Granted: 1979-02-20
Abstract: Abstract of the Disclosure A process for the preparation of cyclohexanones and/or cyclohexanols by catalytic hydrogenation of cyclohexyl hydroperoxides is disclosed.  In the invented process use is made of a finely divided catalyst that is suspended in the reaction mixture and contains one or more noble metals from Group VIII of the Periodic System of Elements, preferably rhodium platinum and/or palladium. With the invented process a high reaction rate can be achieved already at a low reaction temperature and a hydrogen pressure, while the desired products are obtained in a high yield.  Very little catalyst is needed for achieving a given rate of reaction.  The invention permits advantageous application of catalysts with very high noble-metal concentrations.  Favourable alcohol/ ketone ratios can be achieved.  The invention also offers solutions for speci-fic problems which may occur in performing the invented process.  Advantageous incorporation of the invented process into an overall process for the prepara-tion of cyclohexanols and/or cyclohexanones from a cyclohexane via a cyclohexyl hydroperoxide is disclosed.
Patent CA-1039466-A (CA)
Inventor: LIDIKAY LYLE M
IPC: B29C48/25
Filed: 1974-01-17
Granted: 1978-10-03
Abstract: Abstract of the Disclosure The disclosure relates to an apparatus for driving a metering type charge depositing apparatus that includes a con-veyor advancing a plurality of open-topped receiving devices in predetermined relation along a receiving path with means above the path for supplying a constant supply of plastic material along a vertical path toward the receiving path and cutting means for removing a predetermined amount of the constant supply for deposit into a receiving device.  The apparatus for driving includes first drive means for driving the conveyor at a pre-determined rate and second drive means for driving the cutter means, which includes first and second rotating cutters, at a constant rate synchronous to said predetermined rate.  First adjustable means cooperates with the second drive means for co-ordinating the cutter means relative to the conveyor to insure that the severed amounts of plastic material are deposited in the centers of the open-topped receiving devices.  The drive means also includes second adjustable means for varying the engaging relationship of the first and second cutters relative to the constant supply of plastic material to control the orien-tation of the plastic material when it is received into the open-topped receiving devices.
Patent CA-1042428-A (CA)
Inventor: CULLINAN GEORGE J
IPC: A23K1/16
Filed: 1974-03-22
Granted: 1978-11-14
Abstract: AMIDE DERIVATIVES OF VLB AND LEUROCRISTINE           ABSTRACT OF THE DISCLOSURE            The invention relates to process for preparing derivatives of vinblastine, leurosidine, and leurocristine, pharma-ceutical preparations containing the derivatives as the active ingredient and methods for treating neoplastic disease by administering the derivatives to a mammal.
Patent CA-1058793-A (CA)
Inventor: MASUKO TATSUO
IPC: C08L33/00
Filed: 1975-01-29
Granted: 1979-07-17
Abstract: ABSTRACT OF THE DISCLOSURE             The prevent invention provides in a process for blend-ing liquid rubber and carbon black by stirring and dispersing a mixture of a liquid rubber and carbon black, an improvement which comprises mixing 60-150 parts by weight of carbon black with 100 parts by weight of the liquid rubber to produce a pre-liminary dispersion of carbon black and liquid rubber diluting the preliminary dispersion with a liquid rubber to produce composition having a required carbon black content. The present invention thus provides a process for blending liquid rubber and carbon black to prepare a composition of carbon black and liquid rubber in which carbon black is substantially uniformly dispersed, by using a simple high torque mixer, in a simple operation.
Patent CA-1052375-A (CA)
Inventor: JAMES DANIEL S
IPC: C09B29/36
Filed: 1975-04-01
Granted: 1979-04-10
Abstract: ABSTRACT OF THE DISCLOSURE        Azo dyes or the generic formula   wherein R1 an aliphatic group, W is a divalent group of the 1,4-phenylene or 1,4-naphthylene series, m is 0 or 1, and A is a coupling component selected from 1)  a 5- or 6-membered heterocyclic ring containing nitrogen or oxygen in the ring and having an amino, oxo or hydroxy substituent, 2) a naphtholyl group, and 3) an aromatic amine having no substituents in the 4-position to the amino group and at least one aliphatic or cycloaliphatic substituent attached to the amino nitrogen.
Patent CA-1043029-A (CA)
Inventor: COOPER TERENCE A
IPC: C08F36/18
Filed: 1975-04-07
Granted: 1978-11-21
Abstract: ABSTRACT OF THE DISCLOSURE      Addition of a defined tertiary amine in which at least one substituent is a 2-hydroxyethyl- or 2-hydroxypropyl-terminated chain of up to about 50 oxyethylene or 2-oxypro-pylene units to an aqueous alkaline emulsion in which chloro-prene or a mixture of chloroprene with another monomer is undergoing polymerization in the presence of an alkyl mercaptan makes it possible to carry out the polymerization to a high degree of conversion, while at the same time avoiding excessive gel formation.  This invention makes possible a significant increase in polymer yield without sacrifice of polymer quality or performance.
Patent CA-1080445-A (CA)
Inventor: GEDDES ROBERT S
IPC: C01B17/02
Filed: 1975-07-10
Granted: 1980-07-01
Abstract: A B S T R A C T Apparatus for remelting sulphur, including an upstanding tube, or tubes, each being adapted to receive solid sulphur in its top open end and each having a heating jacket therearound.  The sulphur along the tube wall is melted and caused to flow along the wall surface and out of the lower end of the tube.  A heated plate is spaced from the lower end of the tube whereby flow of the melted sulphur from the tube is permitted, additional sulphur being melted by the plate, and flow of solid sulphur is stopped.  The plate is sloped to permit the flow of the liquid sulphur into a trough for flow for storage or use elsewhere.  A method of remelting sulphur by which solid sul-phur is fed into the upper end of a vertical tube.  The tube is heated to melt the sulphur against the tube wall.  A film of melted sulphur is caused to flow down the wall and out of the tube bottom onto a sloping, heated plate and in-to a trough for removal or use.  The flow of solid sulphur is stopped by the plate.
Patent CA-1048199-A (CA)
Inventor: NAKATA TETSUYA
IPC: C08L71/03
Filed: 1975-09-16
Granted: 1979-02-06
Abstract: ABSTRACT      A cured or uncured composition of a homopolymer or copolymer of an epihalohydrin comprising a homopolymer or copolymer of an epihalohydrin, a curing amount of a curing agent therefor and an acid acceptor, characterized in that the curing agent and acid acceptor are free from a cyclic carboxylic acid anhydride and consist, based on 100 parts by weight of the epihalohydrin homopolymer or copolymer, of (a)  a component  selected from the group consisting of 1 to 200 parts by weight of an acid salt of 1 mole of n polybasic carboxylic acid with 1 mole of 1,8-diazabicyclo (5,4,0)undecene-7 and a mixture of 1 to 200 parts by weight of polybasic carboxylic acid and 1 to 10 parts by weight of a neutral salt of 1,8-diazabicyclo (5,4,0)undecene-7, and (b)  1 to 20 parts by weight of a specific metal compound of Group II and Group IVa of the periodie table of elements.
Patent CA-1059156-A (CA)
Inventor: MIILLER WILLIAM C
IPC: C04B35/56
Filed: 1975-10-06
Granted: 1979-07-24
Abstract: Abstract An insulating composition useful for riser sleeves for casting of molten ferrous metal is described.  The composition comprises 30% to 50% refractory fiber, 1% to 35% granular silicon carbide, inorganic binder, organic binder, and refractory filler.  Molten steel at temperatures on the order of 3,000°F can be readily handled by riser sleeves of this composition   The riser sleeves of this invention also afford superior heat insulating properties and allow the molten metal in the riser to remain molten for a longer period.
Patent CA-1056841-A (CA)
Title: Organic compounds which contain uretdione groups and blocked isocyanate end groups
Inventor: MUELLER PETER
IPC: C08L75/04
Filed: 1975-12-31
Granted: 1979-06-19
Abstract: ABSTRACT OF THE DISCLOSURE           The present invention relates to a process for producing polyisocyanates containing uretdione groups and blocked terminal isocyanate groups.  Organic diisocyanates are dimerized, optionally in the presence of phosphine cata-lysts and then reacted with a blocking agent and optionally a chain lengthening agent.  The proportions of blocking agent and chain lengthening agent are chosen such that less than all the isocyanate groups are reacted with chain lengthening agent and such that there are substantially no free isocyanate groups left.  The invention also relates to latent polyisocyanate produced by this process, i.e. those containing ?rethdione groups and blocked terminal isocyanate groups.  The invention is also concerned with the use of such polyisocyanates to make polyurethane resins.
Patent CA-1064111-A (CA)
Inventor: MATTEI ANTHONY
IPC: H03D3/00
Filed: 1976-03-19
Granted: 1979-10-09
Abstract: ABSTRACT         A digital click removal and squelch control circuit for a digital FM receiver.  The digital receiver generates a series of binary number electrical signals each of which is representative of the instantaneous phase angle of a received frequency-modulated electrical signal or signal derived there-from.  The phase angle signals are differentiated to produce binary number electrical signals that represent the rate of change of phase angle, or the instantaneous frequency of the received signal.  During a given time interval, the phase change caused by the modulation of the received signal must be within a range determined by the bandwidth of the received frequency-modulated signal.  Phase changes outside of this range represent electrical noise or clicks and are removed by the click removal circuit of the invention.  If a predeter-mined number of clicks occur during a predetermined time interval, the squelch control circuit of the invention pro-vides a squelch control signal which may be used to disable the output of the FM receiver.  When the click rate decreases, the output of the FM receiver is restored.
Patent CA-1052436-A (CA)
Inventor: VAN DER WAAL JAN
IPC: H01J31/20
Filed: 1976-04-08
Granted: 1979-04-10
Abstract: ABSTRACT              A variation in shape of the shadow mask may occur owing inter alia to thermal effects in a shadow mask tube and consequently mislanding of the electron beams in the direction of the centre of the display screen may occur.           The mislanding is compensated for by means of an eletron-absorbing insulating layer on the display screen, which layer has apertures which are in registration with the luminescent regions of the display screen.  In the case of mislanding of the electron beams, the layer is locally charged negatively and sets up a retarding electric field between the layer and the shadow mask.  The electric field deflects the electron beams away from the centre.  The last-mentioned effect reduces the original mislanding.
Patent CA-1050594-A (CA)
Inventor: ORCUTT FREDERIC K
IPC: F16C32/04
Filed: 1976-04-13
Granted: 1979-03-13
Abstract: ABSTRACT OF THE DISCLOSURE         A spiral-groove self-pressurizing bearing structure is provided with a magnetic lubricant and magnetic means to retain the lubricant in the bearing at rest.  During operation, the spiral grooves pressurize and distribute the lubricant within the bearing structure, and the magnetic retention means prevents entrainment of air into the bearing, and consequent loss of lubricating action.
Patent CA-1037079-A (CA)
Inventor: EWING LLOYD
IPC: H02G3/06
Filed: 1976-04-30
Granted: 1978-08-22
Abstract: PUSH-TYPE COUPLING AND CONDUIT PIPE ASSEMBLY              Abstract of the Disclosure Lengths of pipe are joined together in above- or below-ground telephone conduit systems by flexible sleeves having specified coefficient of friction, column expansibi-lity and pull-out-resistance and containing helically oriented high modulus reinforcement, bonded or encapsulated in elasto-meric material.  The resultant pipe assemblies represent a significant improvement over previously known cemented conduit-coupling arrangements.  Pipe sections may be quickly and econo-mically joined without field application of adhesive, to provide water-tight, pull-out-resistant joints which will accomodate significant bending moments and shearing forces.
Patent CA-1055114-A (CA)
Inventor: SILVERSTEIN SAMUEL C
IPC: H04L25/24
Filed: 1976-06-09
Granted: 1979-05-22
Abstract: ABSTRACT OF THE DISCLOSURE      A regulated current pulse is generated for use in transferring digital data from low level voltage devices to those requiring substantially high current such as teletypewriters.  By utilizing low voltage components, the current pulse level is continuously controlled, isolated form the low voltage source and applled to the load remotely located.
Patent CA-1061840-A (CA)
Inventor: FISCHER KARL
IPC: H01H37/48
Filed: 1976-06-23
Granted: 1979-09-04
Abstract: ABSTRACT OF THE DISCLOSURE          A temperature limiter used as part of  or otherwise in combination with. an electric cooking plate,  An improved switch-ing hysteresis is enabled by a unique construction in which a laterally open recess is formed in a one-piece housing to receive a snap switch, the stationary contact of which is fixedly secured in slot structure adjacent said recess.  A transmission rod is arranged within an expansion sleeve and i  positioned to be spring biased through engagement with the spring of a snap switch.
Patent CA-1102487-A (CA)
Inventor: ROWTON RICHARD L
IPC: C08G18/50
Filed: 1976-08-03
Granted: 1981-06-02
Abstract: POLYURETHANE ELASTOMERS HAVING IMPROVED SAG RESISTANCE                       (D#75,040-F) Abstract of the Disclosure The use of small amounts of an amine-terminated polyether in the B-component of a two-component polyurethane composition results in the immediate thickening of the A and B-components upon mixing to provide an elastomer precursor with improved sag resistance without substantially affecting the workability of the mixed components or the properties of the cured elastomer,  These elastomers are useful as sealants, caulks and surface coatings.
Patent CA-1049889-A (CA)
Inventor: PETERSEN DONALD D
IPC: F16H61/46
Filed: 1976-08-11
Granted: 1979-03-06
Abstract: HYDROSTATIC TRANSMISSION The hydrostatic transmission includes a main pump having a plurality of reciprocating pistons projecting into and biased towards a drive chamber and has both its inlet and its drive chamber connected to a substantially constant pressure charge circuit.  Displacement of the pump is controlled by controlling the fluid flowing from the charge circuit to the inlet.  The pump outlet is connected to the drive chamber through a combined safety and inching valve which normally blocks fluid flow therebetween but which is responsive to excess pressure at the pump outlet to open and increase the pressure in the drive chamber.  The valve is also manually operable through a pedal on the vehicle which can be used to destroke the pump in emergency situations or to provide inching control.
Patent CA-1066910-A (CA)
Title: Procede de mesure de temperature et sonde pour sa mise en oeuvre
Inventor: DEFICIS ALAIN
IPC: G01K5/02
Filed: 1976-08-11
Granted: 1979-11-27
Abstract: Procédé et sonde pour la mesure de température ou de variations de températures.  La sonde comporte un enceinte capillaire dans laquelle est disposé un liquide thermodilatable formant un ménisque réflecteur.  Un premier conducteur optique amène un pinceau de lumière et le dirige vers le ménisque, cependant, qu'un second conducteur ramène la lumière captée vers des moyens d'analyse de lumière.  La sonde peut être utilisée pour les mesures de température dans un large plage ( - 50.degree. C, 150.degree. C), et notamment pour des mesures requérant un grand sensibilité, pour des mesures à effectuer dans des zones d'accès difficiles, pour des mesures exigeant des vitesses de réponses élevées ou encore pour des mesures sous rayonnement électromagnétiques.
Patent CA-1075012-A (CA)
Inventor: SASAKI KANTARO
IPC: C21C1/02
Filed: 1976-09-28
Granted: 1980-04-08
Abstract: ABSTRACT OF THE DISCLOSURE                    A process for dephosphorizing molten pig iron by adding (a) line C???? slag and/or iron oxide (b) iron oxide and/or oxidizing gas, and if necessary (c) fluor???? and/or soda ash to the molten pig iron stored in a treating vessel in order to adjust the amount of CaO to correspond to at least 0.3 times the sum of the amounts of SiO and P2O5 and to adjust the amount of T.Fe to 15 to 50% in the slag com-position after trestment, thereby obtaining a hig dephos-phorisation.
Patent CA-1078748-A (CA)
Inventor: PELTON JOHN F
IPC: B01D21/06
Filed: 1976-10-05
Granted: 1980-06-03
Abstract: SUSPENDED SLUDGE SCRAPER FOR ARCUATE        SEDIMENTATION ZONE               ABSTRACT OF THE DISCLOSURE           Apparatus for collection and removal of settled solids from the bottom part of an arcuate sedimentation zone, comprising a scraper blade suspended by cable means from a bridge and drawn reciprocatingly and repetitively in an arcuate path around the sedimentation zone.  Means are provided for shortening the suspended lengths of the cable means at the approach of the bridge to a radial end wall of the zone so that the scraper blade is drawn toward the wall for radial alignment therewith, thereby eliminat-ing unscraped 'dead space' adjacent the end walls.               S P E C I F I C A T I O N
Patent CA-1058098-A (CA)
Inventor: ANDREAE ERHARD C
IPC: B01D45/08
Filed: 1976-10-19
Granted: 1979-07-10
Abstract: Abstract of the disclosure An extensible gas filter comprises three perforated walls with parallel folds, interconnected along alternate folds to allow accordion-like folding of the filter to a maximum value corresponding to the developed length of the shortest third wall, the walls defining chambers with staggered perforations forming a gas-deviating baffle.