baber/WOPTO huggingface dataset:
Patent CA-2444843-C (CA)
Inventor: BAILEY TIMOTHY J
IPC: G02B6/02
Filed: 2002-03-15
Granted: 2013-05-07
Abstract: A large diameter D-shaped optical waveguide device (9), includes an optional circular waveguide portion (11) and a D-shaped waveguide portion (10) having at least one core (12) surrounded by a cladding (14). A portion of the waveguide device (9) has a generally D-shaped cross-section and has transverse waveguide dimension (d2) greater than about 0.3 mm. At least one Bragg grating (16) may be impressed in the waveguide (10) and/or more than one grating or pair of gratings may be used and more than one core may be used. The device (9) provides a sturdy waveguide platform for coupling ligth into and out of waveguides and for attachment and alignment to other waveguides, for single and multi-core applications. The core and/or cladding (12, 14) may be doped with a rare-earth dopant and/or may be photosensitive. At least a portion of the core (12) may be doped between a pair of gratings (50, 52) to form a fiber laser or the grating (16) or may be constructed as a tunable DFB fiber laser or an interactive fiber laser within the waveguide (10). The waveguide may resemble a short "block" or a longer "cane" type, depending on the application and dimensions used.
Patent CA-2445842-C (CA)
Title: Home networking gateway
IPC: H04L12/28
Filed: 2001-04-26
Granted: 2008-08-05
Abstract: A home networking gateway provides an interface between an HFC network and an in-home network. Full voice and data connection between the HFC network and each device in the in-home network is provided through the interface. A  translator included in the home networking gateway is utilized to provide a mapping between the communication protocols used in the in-home network and the protocols used in the HFC network, eliminating the need for the in-home network to be dependent upon the HFC-specific protocols.
Patent CA-2450581-C (CA)
Title: Analyse de l'innocuite cardio-vasculaire
Inventor: HEYLEN GODELIEVE IRMA CHRISTINE MARIA
IPC: G01N33/15
Filed: 2002-07-02
Granted: 2010-11-02
Abstract: La présente invention concerne des méthodes d'analyse et des nécessaires pour le criblage de composés d'essai relativement à leur aptitude à induire une cardiotoxicité chez un sujet. Ces méthodes d'analyse et ces nécessaires reposent sur la constatation que l'interaction de l'astémizole avec le canal potassique HERG peut être exploitée pour prévoir la cardiotoxicité de composés dans le cadre du développement de nouveaux médicaments et d'autres agents.
Patent CA-2456169-C (CA)
Title: Methods and compositions relating to improved lentiviral vector production systems
Inventor: TRONO DIDIER
IPC: A61K31/7088
Filed: 2002-08-01
Granted: 2012-05-22
Abstract: The present invention provides HIV-derived lentivectors which are multiply modified to create highly safe, efficient, and potent vectors for expressing transgenes for gene therapy. The lentiviral vector comprise various combinations of an inactive central polypurine tract, a stuffer sequence, which may encode drug susceptibility genes, and a mutated hairpin in the 5' leader sequence that substantially abolishes replication. These elements are provided in conjunction with other features of lentiviral vectors, such as a self-inactivating configuration for biosaftey and promoters such as the EF1.alpha. promoter as one example. Additional promoters are also described.  The vectors can also comprise additional transcription enhancing elements such as the wood chuck hepatitis virus post-transcriptional regulatory element.  These vectors therefore provide useful tools for genetic treatments for inherited and acquired disorders, gene-therapies for cancers and other disease, the creation of industrial and experimental production systems utilizing transformed cells, as well as for the study of basic cellular and genetic processes.
Patent CA-2456327-C (CA)
Title: Assemblages d'elements multiples possedant des proprietes de liaison renforcees destines au diagnostic et a la therapie
Inventor: CANTRELL GARY L
IPC: A61K31/513
Filed: 2002-08-13
Granted: 2011-11-29
Abstract: La présente invention concerne un conjugué d'éléments multiples mobile et organisé et une technique d'utilisation permettant de renforcer la liaison de composés liés légèrement à une cible. Une structure lamellaire contenant au moins deux composés de liaison est assemblée dans des conditions dans lesquelles les composés de liaison s'autorégulent dans cette structure lamellaire ou sur celle-ci, formant un ensemble de coopération capable d'une liaison avec une affinité renforcée sur un site d'affinité complémentaire d'une cible. Chaque composé de liaison est lié à la surface lamellaire et peut être connecté par un lieur. Ce conjugué peut contenir une molécule effectrice, telle qu'un agent diagnostique ou thérapeutique, en vue d'une administration à un patient qu'on peut ainsi traiter ou pour qui on peut établir un diagnostic à l'aide de cette molécule effectrice.
Patent CA-2456723-C (CA)
Title: Inhibiteurs de l'activite de her3
Inventor: ULLRICH AXEL
IPC: G01N33/15
Filed: 2002-08-09
Granted: 2016-02-09
Abstract: La présente invention porte sur une composition pharmaceutique comprenant comme agent actif un inhibiteur de l'activité de HER3, notamment un anticorps contre HER3. En outre, l'invention porte également sur l'utilisation de cette composition destinée au diagnostic, la prévention ou le traitement de maladies hyperprolifératives, notamment des maladies tumorales.
Patent CA-2463415-C (CA)
Inventor: VINTEN-JOHANSEN JAKOB
IPC: A61M1/00
Filed: 2002-10-25
Granted: 2012-02-07
Abstract: A catheter (5) adapted for use in passing fluids and medicines therethrough for use in the perfusion or reperfusion of blood or blood-fluid mixtures into the arteries, veins, tissues, conduits, or organs of a patient is disclosed.
Patent CA-2463665-C (CA)
Inventor: FLEMING SCOTT
IPC: G01F1/66
Filed: 1999-06-14
Granted: 2008-12-30
Abstract: An fluid sensor to activate and control various components of an inhalation device. The fluid sensor includes an acoustic element, such as a microphone, positioned within said inhalation device to detect fluid within the device and output signals representative of the frequency and/or amplitude of the fluid. These signals control and activate an electrostatic plate and/or a high frequency vibrator.
Patent CA-2464485-C (CA)
Title: Microneedle transdermal transport device
Inventor: ANGEL AIMEE B
IPC: A61M5/172
Filed: 2002-10-21
Granted: 2010-05-11
Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle (14) with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface.  The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.
Patent CA-2465997-C (CA)
Inventor: MILLER JOHN L
IPC: H04L29/06
Filed: 2004-05-03
Granted: 2016-02-23
Abstract: An extensible data structure for messages in a peer to peer name resolution protocol is presented. This message data structure utilizes a number of fields, each containing a message element. Preferably, the first field is the message header that includes protocol information and identifies the type of message. Each message element contains a number of fields. These message element fields include a type field, a length field, and the content or payload of the message element. In one embodiment, at least ten messages are formed for proper operation of a Peer To Peer Name Resolution Protocol (PNRP), including RESOLVE, RESPONSE, SOLICIT, ADVERTISE, REQUEST, FLOOD, INQUIRE, AUTHORITY, ACK, and REPAIR messages.
Patent CA-2467318-C (CA)
Title: Fasteners for composite material
Inventor: DEHAITRE LON
IPC: F16B35/06
Filed: 2004-05-14
Granted: 2008-12-02
Abstract: A fastener has a shaft, a head at a first end of the shaft, and a point at the other end of the shaft. A first portion of the shaft adjacent the point is threaded. The first portion typically extends about one-half the total length of the shaft. A second portion of the shaft (adjacent the head) is not threaded, but has a plurality of spaced rings. A knurled portion can be provided between the first and second portions, if desired. Conventional symmetrical or asymmetrical thread can be used in the threaded portion, or a three lobe thread can be used.
Patent CA-2468867-C (CA)
Title: Support d'enregistrement presentant une structure de donnees pour la gestion de reproduction de donnees graphiques et procedes et appareils d'enregistrement et de reproduction
Inventor: KIM BYUNG JIN
IPC: H04N9/804
Filed: 2003-09-30
Granted: 2011-05-03
Abstract: La présente invention a trait à un support d'enregistrement comportant une zone d'information graphique présentant au moins un segment d'information d'images graphiques et au moins un segment d'information de palette qui y est enregistré. Chaque segment d'information de palette fournit une information de couleur. Chaque segment d'information d'images graphiques fournit une information de reproduction permettant la reproduction d'une ou de plusieurs images graphiques.
Patent CA-2471212-C (CA)
Inventor: GRIFNO RICHARD
IPC: E21B43/08
Filed: 2004-06-16
Granted: 2008-01-29
Abstract: Methods and systems for automatically inspecting a wire-wrapped well screen are provided. A camera may capture an image of a portion of the screen including at least two facing edge portions of adjacent wraps of wire defining a slot therebetween. A thickness of the slot may be determined based on the image, for example, by calculating a distance between the facing edge portions. The camera may be moved relative to the screen to measure slot thickness at several sample locations along a length of the screen. The screen may also be rotated relative to the camera to measure slot thickness at sample locations at different angular offset locations around the screen. Slot thickness measured at the sample locations may be analyzed to generate an inspection report that could be supplied to a customer with the well screen.
Patent CA-2472608-C (CA)
Title: Improved containers for parenteral fluids
Inventor: SKOLLING OTTO
IPC: B32B7/02
Filed: 1997-04-09
Granted: 2005-12-06
Abstract: A flexible transparent container for improved storage of oxygen sensitive parenterally administerable agents comprising an inner, primary container enclosed in a substantially oxygen impermeable outer envelope with an oxygen absorber, capable of consuming essentially all residual oxygen after the outer envelope is sealed, and for sufficient period also the oxygen penetrating said envelope. The inner container is made of a polypropylene containing flexible polymeric material compatible with lipophilic agents capable of forming both permanent and peelable seals, while the envelope is made of a substantially water impermeable flexible multilayered polymeric material comprising a first outer substantially water impermeable polymeric film with oxygen barrier forming capacity, assembled with a second, inner polymeric film with a supplementary oxygen barrier forming capacity. The container essentially maintains its characteristics after being subjected to sterilization by steam or radiation.
Patent CA-2474731-C (CA)
Inventor: RASSIAS JOHN N
IPC: F41A17/42
Filed: 2003-01-29
Granted: 2009-11-17
Abstract: A holster assembly for a firearm includes a shroud (20, 92, 168) with a muzzle receiving space (31), a firearm holding member (100, 174, 246) and a bias activating assembly mounted in the shroud (20, 92, 168) for biasing the firearm into a stowed position against the holding member (100, 174, 246). A  hood enclosure (166) is movable between open and closed positions. The hood enclosure (166) includes a pair of guide slots (188) within the shroud (20, 92, 168) , a pivot pin (182) and a guide pin (186). The hood enclosure (166) may include an illumination device (238) mounted to the firearm, a hip mount platform (256) to mount a hip mount assembly (34), or a secondary stowage mount (270) to attach a magazine carrier (278), expandable baton carrier (266), etc.. The shroud (20, 92, 168) includes a detent (178) that receives a locking safety lever (146) of the firearm. An L-shaped slot (138, 106, 162) receives a projection from a handle portion (132), a take down button (88), a safety lever (158), or another side extending projection of the firearm.
Patent CA-2477389-C (CA)
Title: Transmitting streams over asynchronous networks
Inventor: SCHOENBLUM JOEL
IPC: H04L29/06
Filed: 2003-01-06
Granted: 2011-06-21
Abstract: An asynchronous network stream transmitter (115) receives a transport stream (126) having content packets and packets to be filtered out and is adapted to selectively encapsulate content packets into network frames (128).
Patent CA-2483028-C (CA)
Title: Diffusion-controlled dosage form and method of fabrication including three dimensional printing
Inventor: WANG CHEN-CHAO
IPC: A61P31/04
Filed: 2003-05-06
Granted: 2011-04-05
Abstract: The invention includes a core-and-shell dosage form or unit in which the core contains API and in which the shell substantially governs the release such as by controlling diffusion of API through the shell. The shell may comprise a release-blocking polymer, and particles of a release-regulating polymer. The shell may be substantially impervious but the release-regulating polymer may become suitable to allow diffusion through it when activated. The core may include a buffer region between the shell and the API-containing portion of the core. The dosage form may include multiple units. The dosage form of the invention is capable of providing a release profile whose time scale can be adjusted by adjusting powder composition, and which may be approximately zero-order release. The invention further includes methods of manufacturing such a dosage form, such as three-dimensional printing.
Patent CA-2486094-C (CA)
Inventor: AMERGA MESSAY
IPC: G01S1/00
Filed: 2003-05-15
Granted: 2011-02-22
Abstract: A system and method are disclosed by which the effects of time of arrival (TOA) errors may be reduced. In a mobile unit, a correlation pulse is generated when a signal transmitted from a base station is detected. The transmitted signal may be reflected or defracted such that multipath signals arrive at the mobile unit. This leads to a distortion in the generated correlation pulse and errors in accurate (TOA) measurements. The present invention models the response function and calculates the width of the pulse using the modeling function with a dynamically adjustable factor to indicate at what point down from the peak the pulse width will be calculated. Based on the calculation of pulse width, a type of multipath signal may be determined and an appropriate correction factor applied to the measured (TOA) to provide a more accurate (TOA) determination. The system may apply correction factors to (TOA) signals from base stations in a mobile telephone unit or from signals received from global positioning system (GPS) satellites.
Patent CA-2496384-C (CA)
Inventor: SEGAL ANDREW H
IPC: A61K38/00
Filed: 2003-08-20
Granted: 2016-11-01
Abstract: The present invention provides a fusion polypeptide which can bind to a cell surface binding moiety (e.g., a carbohydrate) and server as a ligand for a cell surface polypeptide, as well as a vector comprising a nucleic acid encoding for such a fusion polypeptide, and a host cell comprising such nucleic acid. The present invention also provides a composition comprising an antigen bearing target and such a fusion polypeptide, as well as a composition comprising a virus or a cell and such a fusion polypeptide. The present invention further relates to a method of modulating an immune response in an animal using such compositions.
Patent CA-2496681-C (CA)
Inventor: CAIRES ANTONIO CARLOS FAVERO
IPC: C07F15/00
Filed: 2003-08-22
Granted: 2014-08-05
Abstract: The invention relates to cyclopalladated compounds containing bis-diphenylphosphine-ferrocene ligands and their analogues which are active inhibitors of proteins and enzymes, for example, those of the serine peptidase, cysteine-protease, metalo-protease and endopeptidase families, involved in the development and metastases of malignant tumors, e.g. of the thyroid. An exemplary compound is shown in the figure. The compounds are able te modulate the immunological system due to their action on the enzymes and their interaction with DNA molecules.
Patent CA-2496778-C (CA)
Inventor: LOMAX FRANKLIN D JR
IPC: B01D53/047
Filed: 2003-10-10
Granted: 2015-03-24
Abstract: A pressure swing adsorption process including the step of separating a gas mixture by absorbing a gas component in adsorbent beds provided within vessels, where the separating step has at least a two-stage pressure equalization and is performed with no more than five valves per vessel of the plurality of vessels. The process includes an adsorption step, a first pressure equalization step having at least two stages where the pressure decreases, a purge step, and a second pressure equalization step having at least two stages where the pressure increases. A pressure swing adsorption system is provided with vessels each having a first opening connected to a source manifold via a first valve and connected to a waste manifold via a second valve, and a second opening connected to a product manifold via a third valve and connected to an equalization conduit via a fourth valve and a fifth valve.
Patent CA-2498951-C (CA)
Title: Methode permettant d'enrichir l'adn procaryote
Inventor: SCHMIDT KARL-HERMANN
IPC: C12N15/10
Filed: 2003-08-08
Granted: 2013-04-23
Abstract: L'invention concerne un procédé pour enrichir un ADN procaryotique, selon lequel au moins un ADN procaryotique est mis en contact avec au moins une protéine ou au moins un polypeptide, ces derniers étant capables de se lier avec des motifs CpG non méthylés, le complexe ADN-protéine/polypeptide étant ensuite séparé. La présente invention porte également sur un kit pour réaliser ce procédé.
Patent CA-2504022-C (CA)
Inventor: NAKAJI HARUO
IPC: H01S3/10
Filed: 2005-04-13
Granted: 2013-07-16
Abstract: A Raman amplifier can easily reduce the gain variation in Raman amplification even when the power of an input signal varies. The Raman amplifier is provided with (a) an optical fiber that Amplifies an input lightwave to produce an output lightwave, (b) a pump-lightwave-supplying means that supplies pump lightwaves having a plurality of wavelengths to the optical fiber, and (c) a control unit that controls only the power of the pump lightwave having the shortest wavelength among the pump lightwaves so that the average value of the gain of the Raman amplification by the optical fiber in an intended wavelength range can be maintained constant.
Patent CA-2505115-C (CA)
Inventor: PERICHAUD ALAIN
IPC: C08F291/18
Filed: 2003-11-04
Granted: 2012-11-27
Abstract: Surface treatment of a solid substrate comprises coating the substrate with a composition comprising a biocidal monomer, an acrylate, epoxy or vinyl ether comonomer, a radical or cationic photoinitiator and a grafting agent and exposing the coating the UV radiation.  An Independent claim is also included for a solid substrate with a biocidal polymer grafted to its surface, produced as above.
Patent CA-2505473-C (CA)
Title: Systeme de commande de verrouillage sur machine a travailler a roues
Inventor: DAHL JEFFREY A
IPC: B60K28/04
Filed: 2003-11-24
Granted: 2009-11-03
Abstract: L'invention concerne un système de commande (200) pour machine à travailler (100) qui comprend un ensemble entrée actionné par opérateur (300) et un capteur (212) couplé à cet ensemble. Le capteur (212) fournit un signal indiquant la présence de l'opérateur sur une plate-forme d'opérateur (26). Le système de commande comprend aussi un contrôleur (210) relié opérationnel au capteur et recevant un signal fourni par le capteur. En outre, le contrôleur manipule au moins une fonction de la machine à travailler en fonction du signal.
Patent CA-2508199-C (CA)
Title: Appareil et methodes d'occlusion d'une structure anatomique creuse
Inventor: COSGROVE DELOS M III
IPC: A61B17/28
Filed: 2005-05-25
Granted: 2013-05-21
Abstract: Un appareil (10) d'occlusion d'une structure anatomique creuse comprend une pince (12) ayant au moins une première et une deuxième portion de pincement (12a, 12B) adaptées pour être placées sur les côtés opposés d'une structure anatomique. Au moins une de la première et de la deuxième portion de pincement (12a, 12b) est déplaçable vers l'autre d'une position ouverte à une position pincée ou fermée pour réaliser l'occlusion de la structure anatomique. La pince (12) a une forme annulaire configurée pour entourer la structure anatomique creuse dans la position ouverte et une forme aplatie dans la position pincée pour faire l'occlusion de l'intérieur creux de la structure anatomique. La pince (12) est préférablement couverte d'un tissu pour promouvoir la croissance des tissus. Un dispositif de positionnement et d'activation de la pince (20) est fourni pour permettre à la pince (12) d'être utilisée dans une intervention chirurgicale ouverte ou une intervention minimalement invasive.
Patent CA-2510744-C (CA)
Title: Methode, systeme et appareil permettant de previsualiser des documents
Inventor: ROSENBERG JONATHON P
IPC: G06F3/0484
Filed: 2005-06-27
Granted: 2013-12-24
Abstract: Une méthode et un appareil pour générer une prévisualisation de document sont fournis. Selon la méthode, un gestionnaire de prévisualisation fournit une interface à un ou plusieurs prévisualisateurs. Les prévisualisateurs sont des composants logiciels capables de générer une prévisualisation visuelle pour un ou plusieurs types de document. En réponse à une demande de génération de prévisualisation d'un document d'une application hôte, le gestionnaire de prévisualisation permet d'identifier le prévisualisateur approprié pour générer une prévisualisation du document. Le gestionnaire de prévisualisation peut alors appeler le prévisualisateur pour lui indiquer de charger le document et de présenter la prévisualisation dans une sous-fenêtre d'une fenêtre fournie en appelant l'application hôte.
Patent CA-2512417-C (CA)
Inventor: CALDWELL JAMES M
IPC: B23P6/00
Filed: 2005-07-14
Granted: 2013-06-11
Abstract: A method for repairing a damaged portion of a combustor inner liner assembly (48, 80). The method includes removing the combustor (45) from a gas turbine engine (10). After inspecting the combustor (45) to determine whether cracks exists in portions of the inner liner assembly (48, 80), the method includes removing a cracked inner liner assembly (48, 80) from the combustor (45). Then the portion of the inner liner assembly (48,80), comprising a multi-hole panel region (84), an aft lip region (86), an aft seal flange region (87) and an aft panel support leg (88) are separated from the inner liner assembly (48,80). The multi-hole panel region (84) and aft lip (86), where fatigue damage typically exists, along with the aft seal flange region (87), are discarded and a new aft lip region/aft seal flange region and multi-hole panel region are provided. The new parts are joined to the aft panel support leg (88) and the inner liner assembly aft of forward bolt flange region (81) after these parts are refurbished. The inner liner assembly (48,80) is then reattached to the combustor (45) and reassembled into the engine (10).