baber/WOPTO huggingface dataset:
Patent CR-20120450-A (CR)
Title: Anticuerpos reactivos con b7-h3, los fragmentos inmunológicamente activo del mismo y sus usos
Inventor: LOO DERYK T
IPC: A61K39/00
Filed: 2012-08-30
Abstract: La presente invención se refiere a anticuerpos y sus fragmentos que son inmunorreactivos frente al receptor de B7-H3 de mamífero, y más particularmente, humana y a usos de los mismos, particularmente en el tratamiento del cáncer y la inflamación. La invención se refiere por tanto particularmente a anticuerpos reactivos frente a B7-H3 humanizados y a sus fragmentos inmunorreactivos que pueden mediar, y más preferiblemente potenciar, la activación del sistema inmunitario frente a células cancerosas que están asociadas con una variedad de cánceres humanos.
Patent CR-20150217-A (CR)
Title: Inhibidores de histona demetilasas
Inventor: LABELLE MARC
IPC: C07D413/12
Filed: 2015-04-28
Abstract: La presente solicitud describe compuestos capaces de modular la actividad de las histona demetilasas (HDME), que son útiles para la prevención y/o el tratamiento de enfermedades en donde la desregulación genómica está implicada en la patogenia, como por ejemplo el cáncer.
Patent CR-20150230-A (CR)
Title: Método para la desintoxicación de proteínas de gluten de granos de cereales
Inventor: DI LUCCIA ALDO
IPC: A23L5/20
Filed: 2015-04-30
Abstract: El método permite la obtención de harinas desintoxicadas de gluten adecuadas para la preparación de productos de panadería y pasta hecha de trigo. Con el uso del método las proteínas de gluten sufren cambios estructurales que no se activan en patentes sufriendo la enfermedad celíaca, la cascada de citoquininas inflamatorias.
Patent CR-20150310-A (CR)
Title: Solución para preservar conductos vasculares
Inventor: SURYAN MAHENDRA
IPC: A61K38/48
Filed: 2015-06-11
Abstract: Órganos y formulaciones de preservación de tejido con una mejor vida útil de estabilidad, se proporcionan mediante la separación de la formulación en una primera solución que tiene un pH de al menos 7 y una segunda solución que tiene un pH de menos de 7.
Patent CR-20150610-A (CR)
Title: Compuestos de pirimidino sustituido y derivados para combatir plagas de animales
Inventor: NARINE ARUN
IPC: C07D513/04
Filed: 2015-11-10
Abstract: La presente invención provee compuestos novedosos útiles como inhibidores de proteasoma. La invención además provee composiciones farmacéuticas que comprenden los compuestos de la invención y métodos para utilizar las composiciones en el tratamiento de varias enfermedades.
Patent CR-20190561-A (CR)
Title: GARP-TGF-ß ANTIBODIES
Inventor: VAN DER WONING SEBASTIAN
IPC: C07K16/28
Filed: 2018-05-11
Abstract: The present invention relates to antibodies and antigen binding fragments thereof, which bind to a complex of GARP and TGF-ß1, particularly a complex of human GARP and human TGF-ß1. These antibodies and antigen binding fragments exhibit a combination of advantageous properties including high affinity antigen binding and the ability to inhibit the release of active TGF-ß from regulatory T cells. The antibodies and antigen binding fragments of the present invention are relatively resistant to deamidation, isomerization and oxidation, such that they display improved stability.
Patent CR-20210263-A (CR)
Title: Dispositivo de rastreo de seguridad con supresión de alerta con base en zona
Inventor: TRAN QUANG NGOC
Filed: 2021-05-20
Abstract: Un método para activar una alerta de seguridad usando un dispositivo de rastreo, que incluye detectar el movimiento usando un sensor de movimiento del dispositivo de rastreo, determinar que el movimiento detectado cumple con el umbral de movimiento, detectar uno o más puntos de acceso inalámbricos en proximidad al dispositivo de rastreo, determinar que el uno o más puntos de acceso inalámbricos no correspondan a un punto de acceso inalámbrico reconocido, y de conformidad con la determinación que el uno o más puntos de acceso inalámbrico reconocido, activar una alerta de seguridad.
Patent CR-20210536-A (CR)
Title: Forceps drive shaft
Inventor: BLUS THEODORE C
IPC: A61B18/14
Filed: 2020-03-25
Abstract: Surgical forceps can include a drive pin an outer tube, a first jaw, a second jaw, and an inner tube. The outer tube can define a longitudinal axis. The first jaw can be pivotably connected to the outer tube. The first jaw can include a pair of flanges located at a proximal portion of the first jaw, where each flange can include a track receiving the drive pin. The inner tube can be located within the outer tube and can extend along the longitudinal axis. The inner tube can include a pair of arms extending from a distal portion of the inner tube. The drive pin can be securable to the pair of arms. The inner tube can be translatable within the outer tube to drive the drive pin along the tracks to move the second jaw between open and closed positions.
Patent EC-SP034529-A (EC)
Title: Derivado de tiazolidinodiona y su uso como antidiabetico
Inventor: MILLAN MICHAEL
IPC: A61K31/44
Filed: 2003-03-28
Abstract: Se describe un compuesto, sal de potasio de 5-(4-(2-(N-metil-N-(2-piridil)amino)etoxi)bencil)tiazolidino-2,4-diona , o un solvato farmacéuticamente aceptable del mismo, una composición farmacéutica que contiene a dicho compuesto, y el uso de dicho compuesto en medicina, en particular en el tratamiento de diabetes mellitas.
Patent EC-SP066494-A (EC)
Title: Composición y método para tratamiento de condiciones uro-genitales
Inventor: CATANIA ANNA P
IPC: A61K38/08
Filed: 2006-04-07
Abstract: La presente invención está dirigida a una composición y método para tratar condiciones uro-genitales. Una incorporación revelada es una composición farmaceútica para uso en el tratamiento de condiciones uro-genitales en la cual dicha composición comprende un regulador KPV, un primer agente conservante, un disolvente, un alcaloide, un polímero acrílico en base a un ácido, un segundo agente conservante y un agente gelatinizante. Otra incorporación de la invención que se revela es la composición que comprende un regulador CKPV (SEQ ID No. 5), API, Carbopol (r), NF, propilparaben, NF; metilparaben, NF; propilene glicol, USP; ácido edítico (EDTA), USP; 2 M solución de hidróxido de sodio (NaOH); y agua estéril para inyección, USP. También se revela los métodos e indicaciones para el uso de la composición revelada
Patent EC-SP109976-A (EC)
Title: Rendimiento incrementado de grano a traves de la reduccion que es el objetivo en la señalizacion de etileno
Inventor: GALLIE DANIEL R
IPC: C12N15/82
Filed: 2010-02-19
Abstract: La presente invención suministra composiciones y métodos para afectar la vía de transducción de la señal de etileno en las plantas
Patent EC-SP941024-A (EC)
Inventor: NORBERT BERTA I
IPC: A61J3/06
Filed: 1994-01-12
Abstract: Disclosed is an apparatus for coating product (10) with two colors which includes a first coating section, a second coating section and a means for transferring products from the first to the second sections. The first section includes a feeding (80) and loading station for depositing products onto product holders (30) retained in product carrier plates (50,50'). The products are advanced to a first dipping station in which a vacuum chamber (60) having the plurality of vacuum tubes (100) engages a plate and inverts and dips the products to coat a first portion of the product. The plates are then advanced to a first rotating station where another vacuum chamber and vacuum tube device engages the plates and rotates the plates one revolution for spreading the coating over that first portion. The plates are advanced to an elevator where they are raised incrementally to a dryer (130) that extends over the first section of the coating apparatus. The plates are transferred into the dryer where they traverse through the dryer in a controlled manner for curing the coating applied to the first portion. The plates are transferred to a down elevator and returned to the conveyor where they are advanced to a side to side transfer apparatus. The transfer apparatus transfers the products to the second section of the coating apparatus in such a manner to expose on carrier plates the uncoated portion of the products. The plates are then advanced to identical dipping and rotating stations as in the first section and then transferred by an elevator up to a second dryer located above the conveyor in the second section. The plates traverse the second dryer and are returned to the second conveyor by a down elevator where the plates are advanced to an unloading and discharge apparatus. The empty plates are then advanced to the side to side transfer where they are recycled for future use in the apparatus. <IMAGE>
Patent FI-20021779-A (FI)
Inventor: LISKI MARKO
IPC: F16B5/01
Filed: 2002-10-07
Abstract: Cellular sandwich structure elements (1a,1b) are welded together such that the areas where the elements have no surface plate at one side are arranged face to face to bring identical core structures (4) into a superimposed interlocking position. This will bring one side surface plate (2,3) of both elements to cover the area, where the opposite cellular sandwich structure element has no surface plate. An independent claim is also included for a cellular sandwich structure assembly.
Patent FI-20125481-A (FI)
Inventor: HOLMA ANTTI
IPC: H01R13/641
Filed: 2012-05-03
Abstract: Equipment comprising at least one plug-in unit and a body device for receiving the plug-in unit is presented. The plug-in unit comprises an electrically conductive structure (121, 122, 123) having at least one surface area capable of forming a capacitive coupling with a surface area of an electrically conductive part (130, 131) of the body device when the plug-in unit is inserted in the body device. The equipment further comprises a monitoring circuit (124) for generating a signal indicative of electrical properties of a measurement circuit comprising the capacitive coupling and at least one galvanic contact provided by electrical connectors of the plug-in unit and the body device. The generated signal is also indicative of correctness of the installation of the plug-in unit. Thus, the correct installation of the plug-in unit can be electrically indicated and monitored.
Patent GB-1018152-A (GB)
Abstract: 1,018,152. Fuel elements. COMMISSARIAT A L'ENERGIE ATOMIQUE. April 23, 1964 [April 23, 1963], No. 16883/64. Heading G5C. [Also in Division B3] A nuclear fuel element 2 containing e.g. uranium, is encased by a finned sheath 4 which is closed by uranium washers 12, 18 and stoppers 8, 14 welded at 10, 16, respectively. The conductors 26, 28 of thermocouples 20, 22, 24 pass through and are brazed to the stud 30. Inner and outer members 36, 34 slidably engage the stopper extension 32, the inner member being expanded to cause the extension material to flow into the keying grooves of the members. The stud 30 and members 34 and 36, which may all be of stainless steel, are welded together. The sheath and stopper may be of magnesiumzirconium alloy.
Patent GB-1020924-A (GB)
IPC: G06F9/22
Abstract: 1,020,924. Computer microprogramming arrangements. TELEFUNKEN PATENTVERWERTUNGSGESELLSCHAFT. Aug. 22, 1962 [Aug. 25, 1961], No. 32224/62. Heading G4A. Sequence control elements are arranged in a three-dimensional matrix, access to a particular sequence being obtained by defining two coordinates. In an N-bit operation section of a single address instruction word the co-ordinates are defined by the first M and the remaining N-M bits respectively. The arrangement is shown diagrammatically in Fig. 2. The first three bits of the OP section of the word are decoded to mark one out of eight lines 36 which selects one of the top row of elements LS, say LS11. The remaining five bits mark one out of thirty-two lines to select one of the elements Rb, say Rb2. The elements LS11 to LS13 are successively switched by external control pulses and the control elements 0 112  to 0 132  are successively operated to perform various control functions. In Fig. 7 (not shown). The elements shown as having five terminals e.g. Rb2, 37, are bi-stable elements which are primed by having an information input at one of the two input terminals at the lower corners and are switched by a clock pulse T, whereas the elements LO, shown as having three terminals, are primed to produce an output at O by an input at O<SP>1</SP> and one switched by a clock pulse T, while a clock pulse with no input at O<SP>1</SP> resets output O. The first decoders 19, 20 prime elements LS11 and Rb2, respectively. The first clock pulse T sets these elements. If a condition signal is present at terminal 56 the conjunction of outputs from elements LS11 and Rb2 primes circuit 46 and element LS12. If, however, a condition signal is present on terminal 57 elements 46 and LS12 are skipped and the microprogramme jumps directly to element LS13. The chain of elements may be run through several times. Thus element 49 is initially with an output at P. When element LS13 is switched the first time, elements 49 and 53 are switched and, on the next step, a return to the first stage, O 112 , of the chain is made. On reaching O 132  a second time, element 49 has an output at P and element 50 is switched to issue a stop signal. The Specification also describes nanoprogrammes, i.e. sub-routines of microprogrammes. In Fig. 8, the elements LS are control elements of a microprogramme. When element 58 is switched, the chain LNS1 to LNS4 is run through before passing to the next element 60 of the microprogramme. The chain controls the setting of elements LO supplying control potentials to the computer and as shown is subject to condition signals on the unreferenced terminals to run through the sequences LNS1, LNS2, Stop, or LNS1, LNS3, LNS4, Stop. Depending on the parts of the computor used, nanoprogrammes can be run concurrently with a microprogramme (Fig. 9, not shown). There is some mention in the Specification of the second part of the OP section of an instruction being subdivided, one section defining a coordinate as before, and the other section providing condition signals.
Patent GB-1047507-A (GB)
IPC: C10G33/02
Abstract: 1,047,507. Separating fluids from oil-continous emulsions; electrostatic separators. PETROLITE CORPORATION. April 7, 1965 [April 20, 1964], No. 14845/65. Headings B1D, B1M and B2J. In the treatment of oil-continous emulsions to remove gas and water therefrom, the emulsion is pretreated in a lower, gas and free-water, separation zone running substantially the length of the reaction container before subjecting the pre-treated emulsion to electric treatment in the upper interior of the container to coalesce the emulsified water. Emulsion to be treated is fed in through pipe 60 to flow longitudinally beneath an inverted trough baffle structure 45, gas separating out in the upper interior of the baffle structrue to form a gas/emulsion interface 62 and free water dropping to a emulsion/water interface 65. The pretreatment of the emulsion is aided by a U-shaped heater 55 provided within and extending the length of the baffle structure. The interface 65 is at the level of notches 70 in the side walls 51 of the baffle structure through which streams of emulsion droplets pass, and flow upwardly through the body 32 of water in the remainder of the container, being washed by the water before rising through the oil/water interface 30 to the treating space between electrodes 20 and 21. The interfaces are maintained at constant levels by means of floats and valved-draw off pipes. In an alternative embodiment (Figs 4-6 not shown) the baffle structure terminates short of one end wall of the container where it opens into a dwell chamber 85 divided by a partition 86 from the electrode zone. Also the sloping walls of the trough extend laterally to the internal side walls of the container.
Patent GB-1052429-A (GB)
IPC: C07C2/30
Abstract: 1,052,429. Polymerizing ethylene. GULF RESEARCH & DEVELOPMENT CO. Nov. 6, 1963 [Nov. 21, 1962], No. 43761/63. Heading C5E. In the polymerization of ethylene to alphaolefins in the presence of a catalyst of the formula M<SP>1</SP> a M b R c X d . in which M<SP>1</SP> is alkali or alkaline earth metal and a is 0 or 1, M is aluminium gallium, indium or beryllium and b is 0, or 2, R is monovalent saturated aliphatic or alicyclic or aromatic radicals and X is hydrogen or halogen, the sum of c and d being .equal to the valencies represented by the metals provided that when X is halogen c is at least one; the product is oxidized with air or oxygen at 0-100 C. to convert metal alkyl to alkoxide and the alpha olefins are recovered by distillation. The amount of catalyst used is 1 x 10<SP>-4</SP> to 5 x 10<SP>-2</SP> mol per mol of ethylene and polymerization is effected at 140-325‹ C. and up to 1000 atmospheres to maintain liquid phase for 2-300 minutes. Oxidation is effected at up to 140 kg./cm.<SP>2</SP> for 1-120 minutes. The alkoxide may be.hydrolysed to recover the corresponding alcohol.
Patent GB-1054654-A (GB)
IPC: G02B15/00
Abstract: 1,054,654. Zoom lenses. K VOCKENHUBER. Jan.13, 1964 [jan.11, 1963], No. 1468/64. Heading G2J. A varifocal supplementary objective having a zoom ratio of about 3, for use with a main objective, having a relative aperture greater than 1:2À8, comprises a movable positive front component whose five surface powers are respectively Ï 1 - Ï 5  consisting of a cemented doublet L I , L II , of power Ï I + II, whose cemented surface is diverging, and a singlet L III  of power Ï III  a movable negative doublet consisting of a convergent meniscus L IV  cemented to a biconcave lens L V , and a stationary positive singlet L VI  whose front surface is plane or substantially so, wherein: - Optical data are provided for the example shown.
Patent GB-1064418-A (GB)
Abstract: 1,064,418. Primary cells. VARTA PERTRIX-UNION G.m.b.H. Dec. 14, 1964 [Dec. 14, 1963], No. 50747/64. Heading H1B. One of the electrodes of a primary cell is stored separately from the remainder of the cell and is wound in a shaft and arranged to be unwound for use. It is preferably pulled into position by a length of plastics material wound on to a second spindle. A battery may comprise several cells having a common winding device.
Patent GB-1083720-A (GB)
Abstract: 1,083,720. Knitting-machines. SINGER CO. May 27, 1966 [June 1, 1965], No. 23881/66. Heading D1C. In a cylinder and dial machine the cam bed is oscillated by means of a rotatable crank arm pivotally connected to the bed. The machine comprises interconnected cylinder and dial needle beds 20, 30 and cam beds 41, 48. A rotatable crank arm 69 is adjustably, pivotally, connected to the cam bed 41 by a rod 87.
Patent GB-1092741-A (GB)
Abstract: 1,092,741. Capacitors. SOC. ANON. LES CONDENSATEURS SIC-SAFCO. April 12, 1965 [April 20, 1964], No. 15371/65. Heading H1M. The etched or plain aluminium or tantalum cathode foil of an electrolytic capacitor is coated with an adherent absorbent separator layer by immersion in a mixture of water with a water-soluble metallic salt decomposable by heat to an insulating refractory oxide, and a colloidal suspension of a refractory compound, with subsequent drying and pyrolysis. The water-soluble salt may be aluminium nitrate, ferric oxalate, or ferric ammonium oxalate; while the refractory compound may be finely divided silica, alumina, titania, magnesia, zinc oxide, zirconium oxide, aluminium phosphate, talc, or kaolin. The coating, drying and pyrolysis of the foil may be repeated several times.
Patent GB-1227547-A (GB)
Filed: 1968-09-06
Abstract: 1,227,547. Glycyrrhetinic acid derivatives. BIOREX LABORATORIES Ltd. 31 July, 1969 [6 Sept., 1968], No. 42432/68. Heading C2C. The invention comprises compounds of formula wherein R is H or alkyl, R<SP>1</SP> is an aliphatic, cycloaliphatic or aromatic radical, X is carbonyl or sulphonyl or R<SP>1</SP> and X together represent H, and R<SP>11</SP> is H or, when R<SP>1</SP>X is other than H, it can also be acyl (carboxylic or sulphonic); and the preparation thereof from 2-hydroxymethylene - 3,11 - dioxo - (18α or 18#) - olean- 12-en-30-oic acid or an alkyl ester thereof by reduction to give I(R<SP>1</SP>X=R<SP>11</SP>=H) which is then mono- or di-acylated, whereafter the monoacylate (R<SP>1</SP>X = acyl; R<SP>11</SP> = H) may be saponified to regenerate I(R<SP>1</SP>X=R<SP>11</SP>=H).
Patent GB-1227812-A (GB)
IPC: H03H11/38
Filed: 1968-03-15
Abstract: 1,227,812. Signal circulator. POST OFFICE. 12 March, 1969 [15 March, 1968], No. 12766/68. Heading H4R. A signal circulator comprises a number of ports K, K + 1, K + 2 &c., Fig. 2, arranged in a closed cycle, in which a signal applied to one port appears at the following port in the sequence and at no other port. A number of differential amplifiers GK, GK+1, &c., are arranged with each port connected to one input of a respective differential amplifier, and the output of each differential amplifier being applied to both inputs of the following differential amplifier, via respective potential dividers, in such a way as to produce no output in the following differential amplifier. The differential amplifiers may be transistor long-tailed pairs T1, T2, Fig. 3, with a constant current supply transistor T3, the successive stages being coupled by a common collector transistor T4. Differential operational amplifiers may be used, Figs. 4 to 6 (not shown), a particularly simple arrangement (Figs. 5 and 6) being achieved if the operational amplifiers have a gain of two.
Patent GB-1230198-A (GB)
Filed: 1968-06-10
Abstract: 1,230,198. Laminating apparatus. C. F. CRATHERN III. 10 June, 1968, No. 27531/68. Heading B5N. Sheets 16, which may be of cardboard, are laminated one by one, in proper registration, to sheets 14, which may be of paper, fed intermittently on a conveyer 11, by apparatus including a frame 13 for supporting a sheet 16, which is movable linearly and angularly by power means, and a plunger 15 by which each sheet 16 is pressed out of the frame and on to a sheet 14, the sheets 14 being coated on their upper surfaces with adhesive. The sheets 16 may be fed one by one from a stock 30 on to the frame 13 where they are resiliently supported by brushes 28. The frame 13 carries a pair of lamp/photo-cell units 9a, 9b, each of which detects when its side of the frame 13 and the corresponding side of the leading edge of a sheet 14, which reflects light from the lamp to the photo-cell, are in a predetermined relationship, and controls a corresponding hydraulic actuator 18a, 18b which acts on the corresponding side of the frame through a rod 19a, 19b, and a pivot 20a, 20b. In operation, the conveyer is operated to bring a sheet 14 into an approximate position beneath the plunger 15 and then the hydraulic actuators 18a, 18b are caused to move the frame towards them, each actuator being independently stopped by its photo-cell so that the frame is moved along, and angularly, to bring the edge of the sheet 16 lying adjacent to the photo-cells into parallelism with the leading edge of the sheet 14 and into a predetermined position in relation to it. The plunger 15 is then actuated to press the sheet 16 on to the sheet 14, and finally the frame 13 is returned to its initial position. In one modification, Fig. 3 (not shown), each lamp/photo-cell unit incorporates an adjustable mirror by which the light beam is reflected and which is resiliently mounted and arranged so that it is deflected by each sheet 16 as the latter is moved by the plunger 15; and in another modification, Fig. 4 (not shown), a third lamp/ photo-cell unit determines the lateral positioning of a sub-frame for the sheet 16.