Patent SG-11201906497Y-A (SG)
Title: System and method with fiducials of non-closed shapes
Inventor: VIECELI JOHN S
IPC: G01N21/64
Filed: 2018-01-31
Abstract: WO 18/ 1445 63 Al NUCLEOTIDE DELIVERY SYSTEM 4 ! 28 12 IMAGING SYSTEM DATA ANALYSIS SYSTEM / 16 p DOW Ror N E S ss T l i t N EA t M r / 18 STORAGE SYSTEM (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 09 August 2018 (09.08.2018) WIP0 I PCT omit VIII °nolo 010 Ho min loll mom ow (10) International Publication Number WO 2018/144563 Al (51) International Patent Classification: GO1N 21/64 (2006.01) (21) International Application Number: PCT/US2018/016175 (22) International Filing Date: 31 January 2018 (31.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1701689.0 01 February 2017 (01.02.2017) GB (71) Applicant: ILLUMINA, INC. [US/US]; 5200 Illumina Way, San Diego, California 92122 (US). (72) Inventors: VIECELI, John S.; 1498 Flair Encinitas Dri- ve, Encinitas, California 92024 (US). NEMIROSKI, Alex; 5205 Fiore Ten, Apt. B410, San Diego, California 92122 (US). BELITZ, Paul; 5200 Illumina Way, San Diego, Cal- ifornia 92122 (US). LANGLOIS, Robert; 5200 Illumi- na Way, San Diego, California 92122 (US). BOWEN, M. Shane; 5200 Illumina Way, San Diego, California 92122 (US). CHAN, Danny Yuan; 5200 Illumina Way, San Diego, California 92122 (US). VENKATESAN, Bala Mu- rali K.; 499 Illinois Street, Suite 210, San Francisco, Cal- ifornia 94158 (US). HAN, Hui; 5200 Illumina Way, San Diego, California 92122 (US). SAMIEE, Kevan; 5200 Il- lumina Way, San Diego, California 92122 (US). TANNER, Stephen; 5200 Illumina Way, San Diego, California 92122 (US). (74) Agent: DIERKER, Julia Church et al.; Dierker & Ka- vanaugh, P.C., 3331 W. Big Beaver Road, Suite 109, Troy, Michigan 48084 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, = (54) Title: SYSTEM AND METHOD WITH FIDUCIALS OF NON-CLOSED SHAPES (57) : Fiducial markers are provided on patterned arrays of the type that may be used for molecular analysis, such as sequencing. The fiducials may have configurations s Y 32 that enhance their detection in image or detection data, that facilitate or improve process- 2o. ing, that provide encoding of useful information, and so forth. Examples of the fiducials 22 12 may include a non-closed shape that may encode information, allow for bubbles to es- cape during manufacture, and provide additional advantages over closed shape fiducials. X26 i FLUSH STATION ( 3° DEBLOCK STATION 10 FIG. 1 [Continued on next page] WO 2018/144563 Al MIDEDIMOMMIDIRE1013010MOHMITHEIS EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))