Patent SG-11201804220S-A (SG)
Title: Activated stem cells and systemic treatment methods for infected wounds
Inventor: DOW STEVEN W
IPC: A61P31/00
Filed: 2016-12-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -' Organization International Bureau (43) International Publication Date ..... ..sr.1 15 June 2017(15.06.2017) WIPO I PCT (10) WO International 111111111111311111111111111111111111111111111111111111111111111111111311111111111111111 2017/100328 Publication Al Number (51) International Patent Classification: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, A61K 35/00 (2006.01) A61P 17/00 (2006.01) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, A61K 35/12 (2015.01) A61P 31/00 (2006.01) HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, (21) International Application Number: MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, PCT/US2016/065392 OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (22) International Filing Date: SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, 7 December 2016 (07.12.2016) TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (25) Filing Language: English (84) Designated States (unless otherwise indicated, for every (26) Publication Language: English kind of regional protection available): ARIPO (BW, GH, (30) Priority Data: GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, 62/264,077 7 December 2015 (07.12.2015) US TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (71) Applicant: COLORADO STATE UNIVERSITY RE- DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, SEARCH FOUNDATION [US/US]; P.O. Box 483, Fort LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, Collins, Colorado 80522 (US). SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (72) Inventors: DOW, Steven W.; 8 Blue Grouse Ridge Road, GW, KM, ML, MR, NE, SN, TD, TG). Littleton, Colorado 80127 (US). CHOW, Lyndah; 2457 Declarations under Rule 4.17: Forecastle Dr, Fort Collins, Colorado 80524 (US). JOHN- - as to applicant's entitlement to apply for and be granted a SON, Valerie; 808 East Laurel Street, Fort Collins, Color- patent (Rule 4.170) ado 80524 (US). Published: (74) Agents: STOCK, Christina K. et al.; Cooley LLP, 1299 Pennsylvania Avenue, NW, Suite 700, Washington, Dis- — with international search report (Art 21(3)) trict Columbia 20004 (US). of — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of (81) Designated States (unless otherwise indicated, for every kind of national available): AE, AG, AL, AM, amendments (Rule 48.2(h)) protection AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, 1-1 .4t GC ei M O O 1-1 N 1-1 C:= (54) Title: ACTIVATED STEM CELLS AND SYSTEMIC TREATMENT METHODS FOR INFECTED WOUNDS ei 0 (57) : Provided herein are compositions containing an infusion ready population of activated, allogeneic mesenchymal stem ,1 . cells and one or more pharmaceutically acceptable carriers, diluents, or excipients. Also provided are methods of treating infected wounds in mammals by administering an effective amount of activated mesenchymal stem cells to the mammal.