baber/WOPTO huggingface dataset:
Patent NZ-532221-A (NZ)
Title: New isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them
Inventor: POISSONNIER-DURIEUX SOPHIE
IPC: A61P25/06
Filed: 2004-04-08
Abstract: Described is a compound of formula (I): wherein n is l, 2 or 3, A represents a group -NR-C(=Z)-R', -C(=Z)-N(R)-R', or a group -NR-C(=Z)-N(R')-R", wherein: Z represents a S or O; R and R", which may be identical or different, each represents a H or alkyl group; R' represents an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkyl-alkyl, aryl, aryl-alkyl, heteroaryl or heteroaryl-alkyl group; X represents N or N-R1 wherein R1 represents a H or alkyl, cycloalkyl, cycloalkyl-alkyl, aryl, aroyl, aryl-alkyl, heteroaryl, heteroaroyl or heteroaryl-alkyl group; R2 represents an alkoxy, cycloalkoxy or cycloalkyl-alkoxy group Provided are processes for the preparation of compounds if the formula (I) and descriptions of their use in the preparation of medicaments for treatment of disorders of the melatoninergic system.
Patent NZ-532384-A (NZ)
Title: Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
Inventor: BIGGE CHRISTOPHER FRANKLIN
IPC: A61P7/02
Filed: 2002-11-14
Abstract: Disclosed herein are compounds of formula (I), wherein A, B, C, G, and W1 are the substituents as defined in the specification, and pharmaceutically acceptable salt thereof, that are useful to treat thrombotic disorders. Also disclosed are pharmaceutical compositions comprising one or more compounds of formula (I), processes for preparing compounds of formula (I), and intermediates useful for preparing compounds of formula (I). These compounds of formula (I) are cyclic amino acid derivatives or proline derivatives that exhibit inhibitory effects of the serine protease factor Xa.
Patent NZ-535967-A (NZ)
Title: Multilumen catheters and methods for their use
Inventor: CONSTANTZ BRENT R
IPC: A61F2/958
Filed: 2003-03-18
Abstract: A multilumen catheter is provided. The catheter (10) include a proximal end (14) and a distal end (12) separated by a non-coaxial multilumen tube, and includes a multiport manifold (18) at its proximal ends, where at least two of the ports (11a, 11c) of the multiport manifold comprise luer valves (15a, 15c). The catheter contains or is in fluid communication with an acidic dissolution fluid. Also provided are systems for use in flushing a vascular site with fluid, usually at least two different fluids, where the subject systems are made up of two multilumen catheters according to the subject invention, where one of the catheters is inserted inside of the other. In addition, kits comprising various components of the subject systems, e.g., at least two different multilumen catheters, are provided. The subject multilumen catheters, systems and kits find use in a variety of different applications in which it is desired to flush a vascular site with at least one and preferably two different fluids, where particular applications of interest include the treatment of vascular lesions.
Patent NZ-536516-A (NZ)
Title: Fungicidal seed treatment agent for oilseed rape
Inventor: PUHL THOMAS
Filed: 2003-05-21
Abstract: Disclosed is a method for combating fungi in oilseed rape wherein the oilseed rape seed is treated with a composition comprising fluquinconazole and prochloraz.
Patent NZ-538826-A (NZ)
Title: Thiazolopyrimidinone compound to be used in therapy to treat a chemokine mediated disease such as asthma, osteoporosis or cancer
Inventor: BONNERT ROGER VICTOR
IPC: A61P29/00
Filed: 2003-09-16
Abstract: A thiazolopyrimidinone compound of formula (I), pharmaceutically acceptable salt and solvate thereof is disclosed, wherein the compound is suitable for use as a medicament for the treatment of asthma, allergic rhinitis, COPD, inflammatory bowel disease, osteoarthritis, osteoporosis, rheumatoid arthritis, psoriasis and cancer.
Patent NZ-539103-A (NZ)
Title: Geotechnical barrier
Inventor: LEGGE KELVIN ROBERT
IPC: E02D31/00
Filed: 2003-09-30
Abstract: A geotechnical barrier includes a first barrier layer; a second barrier layer overlying the first barrier layer and spaced therefrom, the first and second barrier layers defining, at least in part, a fluid passageway having an inlet and an outlet; and fluid displacement means for displacing a fluid through said fluid passageway from the inlet to the outlet. The invention extends to method for constructing and operating a geotechnical barrier and to a geosynthetic barrier and a geocomposite geosynthetic barrier.
Patent NZ-539718-A (NZ)
Title: Escape device
Inventor: LEE TERRY VICTOR
IPC: A62B1/10
Filed: 2003-09-03
Abstract: An escape device characterized in that the device includes a cable and a rotatable cable dispensing assembly from which said cable is dispensed under load, a braking mechanism operatively connected to said rotatable cable dispensing assembly, said braking mechanism characterised by a brake drum and a brake drum spinner frame, wherein the brake drum spinner frame is pivotably connected to a plurality of brake pad holders adapted to house a respective brake pad including at least one engagement surface, said brake pad holder is biased such that at least a portion of said engagement surface is in contact with said brake drum at all times and at least some braking force is applied when said escape device is at rest whereby as the rotation of said brake drum spinner frame increases the pressure 15 applied by the brake pad on said brake drum and the total area of said engagement surface in contact with the brake drum increases, wherein a braking response of the braking mechanism is proportional to the rate at which cable is dispensed from the rotatable cable dispensing assembly.
Patent NZ-540269-A (NZ)
Title: [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide derivatives having inhibitory effect upon the interaction of CAMs and leukointegrins, useful in the treatment of inflammatory disease
Inventor: KELLY TERENCE ALFRED
IPC: A61P37/00
Filed: 2003-10-27
Abstract: Disclosed are derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide represented by formula (I), wherein the variables are as defined in the specification. These compounds exhibit good inhibitory effect upon the interaction of Cellular Adhesion Molecules (CAMs) and Leukointegrins and are thus useful in the treatment of inflammatory disease.
Patent NZ-545182-A (NZ)
Title: Sea water treatment method and system operable to raise the pH of the liquid solution produced by exhaust gas desulfurisation by mixing the solution with sea water and then aerating the solution
Inventor: TSUCHIYAMA YOSHIHIKO
IPC: C02F1/66
Filed: 2005-01-27
Abstract: A sea water treatment method is disclosed. The seawater treatment method comprises the steps of: (a) mixing a sulfur-absorbing solution produced by sea water desulfurization with sea water to adjust the pH of the sulfur-absorbing solution and sea water to a value higher than 5.5 but lower than 6.5, and (b) the further raising the pH of the sulfur-absorbing solution and sea water to a value higher than 7 by aeration.
Patent NZ-546524-A (NZ)
Title: Voice prosthesis device
Inventor: NELSON JESSE N
Filed: 2006-04-11
Abstract: A voice prosthesis device (20) for insertion into a tracheoesophageal opening of a wearer and method of its manufacture are disclosed. The voice prosthesis device provides a passageway (22) through the tracheoesophageal opening and is retained in place by a tracheal flange (24) adjacent a tracheal end and an esophageal flange (26) adjacent an esophageal end. The passageway includes a first stop extending inwardly from a sidewall of the passageway between the tracheal and esophageal ends, and a plurality of second stops (46) extending inwardly from the sidewall of the passageway between the first stop and the esophageal end of the passageway. A valve mechanism is disposed within the passageway to permit flow through the passageway from the tracheal end and impede flow through the passageway from the esophageal end.
Patent NZ-547518-A (NZ)
Title: Crystal of salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)amino-phenoxy)-7-methoxy-6-quinolinecarboxamide or of solvate thereof and processes for producing these
Inventor: MATSUSHIMA TOMOHIRO
IPC: C07D215/48
Filed: 2004-12-22
Abstract: Provided is a crystalline form of 4-(3 -chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide, wherein said crystalline compound is the hydrochloride of said compound, the hydrobromide of said compound, the p-toluenesulfonate of said compound, the sulfate of said compound, the methanesulfonate of said compound or the ethanesulfonate of said compound, or the solvate of said salt. Further provided are processes for preparing the compounds, anti-tumor agents comprising the compounds and use of the compounds in the manufacture of prophylactic or therapeutic agents for a disease in which angiogenesis inhibition is effective.
Patent NZ-548307-A (NZ)
Title: An phonograph disc encoding position and velocity data used with a turntable to control other media or systems
Inventor: WARDLE SCOTT A
IPC: G11B19/00
Filed: 2005-01-13
Abstract: A system for digitally capturing turntable techniques is disclosed. The system requires the use of an encoded stereophonic grooved phonograph record. The record is created by recording the output from a signal generator module that generates at least one high powered pilot signal and a plurality of lower-powered carrier signals. Each of the lower-powered carrier signals is modulated by a stream of symbols derived from an encoding of a plurality of binary values, each binary value corresponding to a certain prescribed segment of a groove trajectory of the record. When played with the use of a turntable (71) and decoded by a computer using suitable software, the encoded information on the record may be used to determine the relative velocity and position of the turntableÆs stylus with respect to the record. This velocity and position information can then be used to control other media or systems, for example digitally recorded music.
Patent NZ-551115-A (NZ)
Title: Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
Inventor: PHADKE AVINASH
IPC: C07D213/85
Filed: 2005-05-17
Abstract: Disclosed are a number of substituted aryl acylthioureas and their pharmaceutically acceptable salts; wherein the specification lists the specific names of preferred compounds that are inhibitors of viral replication and are suitable for treating infectious diseases include viral infections, particularly HCV infections in human patients suffering from an infectious disease, and are also suitable for treating other animals, including livestock and domesticated companion animals, suffering from an infectious disease.
Patent NZ-553847-A (NZ)
Title: Single variable domain monovalent for binding to CD40L (gp39)
Inventor: GRANT STEVEN
IPC: A61K39/395
Filed: 2005-09-16
Abstract: Disclosed is the use of an antibody polypeptide comprising an antibody single variable domain polypeptide in the preparation of a medicament for treating or preventing a symptom of autoimmune disease, wherein said single variable domain polypeptide is monovalent for binding to CD40L (gp39) and antagonizes an activity of CD40 or CD40L or both.
Patent NZ-561746-A (NZ)
Title: Roflumilast for the treatment of pulmonary hypertension
Inventor: BEUME ROLF
IPC: A61K31/5025
Filed: 2006-04-12
Abstract: Disclosed is the use of a compound selected from the group consisting of Roflumilast,(also known as 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-difluoromethoxy)benzamide) a pharmaceutically acceptable salt of Roflumilast, Roflumilast-N-Oxide and a pharmaceutically acceptable salt of Roflumilast-N-Oxide in combination with SILDENAFIL (also known as 1-[4-ethoxy-3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenylsulfonyl]-4-methylpiperazine or a pharmaceutically acceptable salt thereof for the production of a pharmaceutical composition, combination product or kit for the preventive or curative treatment of pulmonary hypertension.
Patent NZ-563797-A (NZ)
Title: Improved perfluorinated membranes and improved electrolytes for redox cells and batteries
Inventor: KAZACOS GEORGE CHRISTOPHER
IPC: H01M10/0565
Filed: 2006-06-19
Abstract: Disclosed is a redox cell comprising: a positive half-cell in communication with a positive half cell solution that includes a first supporting electrolyte selected from the group consisting of H2SO4, HBr and HBr/HCl mixtures and at least one vanadium ion selected from the group consisting of vanadium (llI), vanadium (IV) and vanadium (V); a negative half-cell in communication with a negative half cell solution that includes a second supporting electrolyte selected from the group consisting of H2SO4, HBr and HBr/HCl mixtures and at least one vanadium ion selected from the group consisting of vanadium (II), vanadium (III) and vanadium (IV); and a cast perfluorinated cation exchange membrane located between the positive half cell and the negative half cell and in contact with the positive half cell solution and the negative half cell solution and wherein the perfluorinated membrane includes a polymer selected from the group consisting of a PTFE, perfluorosulfonic acid and a perfluorosulphonic acid/PTFE copolymer.
Patent NZ-566696-A (NZ)
Title: Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
Inventor: DESAI NEIL P
IPC: A61K31/337
Filed: 2006-08-30
Abstract: Disclosed is a composition comprising a) nanoparticles comprising a poorly water soluble pharmaceutical agent and albumin, b) an edetate, and c) sucrose, wherein significant microbial growth is inhibited in the composition. Further disclosed is a sealed vial comprising the said composition, a kit comprising the said composition, and the use of the said composition for the manufacture of a medicament for treating a disease. Also disclosed is a method of preserving the said composition.
Patent NZ-571722-A (NZ)
Title: Positve airway pressure PAP system for treating sleep-disordered breathing, with reduced calibration through pressure monitoring, estimating vent flows and mask leak thesholds
Inventor: SOMAIYA CHINMAYEE
IPC: A61M16/00
Filed: 2007-06-05
Abstract: A positive airway pressure (PAP) system with a PAP device, a patient circuit with an air delivery conduit with mask and tube interface unit, a controller monitor operable to measure a parameter indicative of a patient's condition over a period of time; and the controller determines the amount of mask leak and measures the mask leak against at least one predetermined mask leak setpoint threshold. The PAP device is configured to deliver therapeutic treatment pressures based on a reduced calibration being independent of the patient circuit, and vary or change to change the pressure delivered by the fan motor variable speed drive when the monitored parameter indicates a lack of patient improvement, provided that the mask leak is classified as being below the at least one predetermined mask leak value. The sensors include an air pressure and flow rate sensor and noise sensor to measure snore sound. The processor has an automatic calibration learning system.
Patent NZ-572736-A (NZ)
Title: Improvements in delivery devices
Inventor: POMROY WILLIAM ERNEST
IPC: A61D7/00
Filed: 2008-11-11
Abstract: An end cap for a bolus housing (15) is disclosed. The end cap includes a sealing portion, which comprises a sleeve (1) and a plug (8), that covers the open end of a bolus housing, and a skirt (5) depending from the circumference of the end cap, the skirt being configured such that the sides of the end cap are substantially parallel to the side of the bolus housing and the interior of the end cap substantially contacts the exterior of the bolus housing. In one embodiment, the end cap includes a collar (12) that surrounds a substantial portion of the bolus housing, and the skirt is configured to engage with the collar. A method of manufacturing an end cap for a bolus housing is also disclosed.
Patent NZ-573347-A (NZ)
Title: Laser guide for saws having arbours
Inventor: NASH DEREK J
IPC: B23K26/02
Filed: 2007-12-05
Abstract: A laser guide for saws having arbors is disclosed. The laser guide comprises a light source; first and second housings; a seal between the first and second housings to define an interior space where the light source is located and an outer portion; a lens located in the first housing; and a seal between the lens and the first housing. The seal between the lens and the first housing and the seal between the first and second housings create a liquid-tight seal to prevent liquid from travelling from the outer portion into the interior portion. (62) Divided Out of 564043
Patent NZ-573364-A (NZ)
Title: A foldable bed comprising a pivoting device that includes a drive device with motor and transmission
Inventor: BOCK KLAUS
IPC: A47C20/08
Filed: 2007-05-08
Abstract: A pivoting device (12) for a bed (1) is disclosed. The bed (1) comprises a bearing construction (2) that provides bearing surface (3) for a mattress. The bearing construction (2) is formed by bearing segments (4) which are pivotable relating to one another. The pivoting device (12) is respectively arranged between two adjacent bearing segments (4). The pivoting device (12) includes a drive device (13). The drive device (12) includes a shaft (17) flanged to the transmission on the drive device (13). The shaft (17) is formed by two semi shafts (18, 19). Each of the semi shafts (18, 19) is accommodated in housing (27). The pivoting device (12) further includes a supporting element that consists of two supporting segments (23). Each of the supporting segments (23) is formed by the housing that accommodates the respective semi-shaft (18, 19). .
Patent NZ-573792-A (NZ)
Title: Treatment of ischemic disease using erythropoietin mobilised mononuclear cells
Inventor: MATSUMOTO TOSHIO
IPC: A61K35/15
Filed: 2007-06-07
Abstract: Disclosed is the treatment of ischemic diseases by using mobilised peripheral blood mononuclear cells (PBMCs), in particular CD34-positive cells. The PBMCs are obtained from a subject that has been administered with erythropoietin (EPO) 3-12 days prior to collecting the peripheral blood. The cells can also be used for stimulating revascularisation in a subject.
Patent NZ-574002-A (NZ)
Title: [1,2,4]Triazolo[4,3-a]pyridine derivatives
Inventor: ALBRECHT BRIAN
IPC: C07D471/04
Filed: 2007-07-13
Abstract: Disclosed are [1,2,4]triazolo[4,3-a]pyridine derivatives as represented by the general formula (I), wherein: J is N; W is CR2b; Z is -O-, or -NR5-; Z* is -O-, -S(O)v-, or -NR5-; R1 is aryl, heteroaryl or heterocyclo any of which may be optionally independently substituted with one or more R10 groups as allowed by valence; R2 is cycloalkyl, cycloalkenyl, heterocyclo, aryl, heteroaryl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkyl, any of which may be optionally independently substituted with one or more R10 as allowed by valence; n is 0, 1 or 2; q and t are each independently 0 or 1; v is 0, 1 or 2; and wherein the remaining substituents are as defined herein. Representative compounds include 4-((6-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methyl)phenol and 3-(4-methoxybenzyl} -6-(pyrrol-2-yl)-[1,2,4]triazolo[4,3-a]pyridine. Further disclosed is a pharmaceutical composition which comprises a compound as defined above together with a pharmaceutically acceptable vehicle or carrier; for treating cancer, for treating HGF mediated disorders or for reducing metastasis in a tumor.
Patent NZ-577826-A (NZ)
Title: Network-controlled e-utran neighbour cell measurements
Inventor: KAZMI MUHAMMAD
IPC: H04B17/00
Filed: 2008-02-04
Abstract: A method in a radio base station of a telecommunication network for configuring a user equipment to perform one or more downlink measurements on at least one neighbour cell within a coverage area including one or more neighbour cells is disclosed. The cells operate with the same or different transmission bandwidth. Also disclosed is the radio base station of a mobile telecommunication network, comprising means for performing the method. The method for configuring a user equipment to perform one or more downlink measurements on at least one neighbour cell within a coverage area including one or more neighbour cells comprises signalling a common measurement bandwidth over which the user equipment shall perform the neighbour cell measurements. This method further comprises instructing the user equipment how to report a result of the measurements. A method in a user equipment for performing downlink measurements on one or more cells according to a received measurement configuration is disclosed. The method for performing downlink measurements on one or more cells according to a received measurement configuration comprises the steps of receiving measurement configuration information from a radio base station; acquiring information on a common measurement bandwidth from the serving cell over which the measurement is to be performed; performing measurements of the neighbour cells over the common measurement bandwidth; and reporting the measurements to the network. Also disclosed is the user equipment in a mobile telecommunication network comprising means for performing the method.
Patent NZ-581328-A (NZ)
Title: Oil and water repellent core-shell fluoropolymer emulsion
Inventor: WANG YING
IPC: C08F265/04
Filed: 2008-07-22
Abstract: An oil- and water-repellent core-shell emulsion polymer is disclosed, which comprises: (A) a core composition, prepared from a first polymerization, comprising, on a water-free and surfactant-free basis, components (a) and (b): (a) from about 40 to about 95 % by weight of one or more monomers selected from the group consisting of styrene; alkyl substituted styrene wherein said alkyl is a linear, cyclic or branched hydrocarbon having 1 to about 18 carbons; and alkyl (meth)acrylate wherein said alkyl is a linear, cyclic or branched hydrocarbon having from about 6 to about 18 carbons; and (b) from about 5 to about 60 % by weight of one or more monomers selected from the group consisting of vinylidene chloride, vinyl chloride, and combinations thereof; and (B) a shell composition, prepared from a second polymerization in the presence of the core composition, comprising, on a water-free and surfactant-free basis, components (c) and (d): (c) from about 50 to about 85 % by weight of one or more fluorinated monomers of formula (I), (II) or (III): (I) Rf1(CH2)m Z-C(O)-C(R1)=CH2(II) Rf2(CH2CF2)q(CH2CH2)rZ-C(O)-C(R1)=CH2(III) Rf3O(CF2CF2)Q(CH2CH2)rZ-C(O)-C(R1)=CH2wherein the substituents are as defined in the specification. A method of treating a fibrous substrate to impart oil repellency and water repellency by applying to the surface of the substrate said core-shell emulsion polymer is also disclosed.
Patent NZ-581849-A (NZ)
Title: Dairy platform measurement systems and methods
Inventor: NILSON ROSS RICHARD
IPC: A01J5/00
Filed: 2006-09-08
Abstract: A system for measuring the operational performance of a milking plant is disclosed. The system comprises a platform position measuring device (7) configured to measure the position of a rotating dairy platform; a cow ID reader (6) configured to collect a plurality of cow ID reads over a period of time; and a processor (11) configured to receive platform position information from the position measuring device and the collected cow ID reads from the ID reader, and to determine motion information from the platform position information and determine performance data from the motion information and the collected cow ID reads. (62) Divided Out of 569146