baber/WOPTO huggingface dataset:
Patent NZ-542500-A (NZ)
Title: Methods of determining a chemotherapeutic regimen based on loss of heterozygosity at the thymidylate synthase locus
Inventor: DANENBERG KATHLEEN D
IPC: C12Q1/68
Filed: 2004-02-20
Abstract: Disclosed is a method of determining a response to a chemotherapeutic regimen based on loss of heterozygosity at the thymidylate synthase locus in cancer tissue. The method comprises determining normal tissue genotype for thymidylate synthase of a patient; determining tumor tissue genotype for thymidylate synthase of said patient; comparing the normal tissue genotype with the tumor tissue genotype; determining whether a loss of heterozygosity at the thymidylate synthase locus has occurred in the tumor tissue based on the comparison of the genotypes; and selecting a chemotherapeutic regimen based on the loss of heterozygosity in the tumor sample.
Patent NZ-543270-A (NZ)
Title: Operating method for a wind park
Inventor: WOBBEN ALOYS
IPC: F03D7/00
Filed: 2004-04-19
Abstract: Provided is a method for production of reconstituted rat embryos by nuclear transfer including the following steps: (a) removal of a rat ovocyte and maintenance in an appropriate medium; b) insertion of a rat cell nucleus into the recipient rat ovocyte previously maintained in vitro to obtain a reconstituted ovocyte (nuclear transfer); (c) activation of the reconstituted ovocyte obtained in step b) to obtain a reconstituted embryo; wherein the recipient rat ovocyte removed is maintained at the metaphase stage of the second meiotic division by maintenance in an appropriate medium including a reversible proteasome inhibitor, wherein the reconstituted ovocyte is activated by exposure to an appropriate medium including an activation inducer (activation medium). Further provided are methods using specified reversible proteasome inhibitors and activation inducers as well as rats when produced by the method.
Patent NZ-543562-A (NZ)
Title: Package having reclosable pour spout and method of forming same
Inventor: YEAGER JAMES W
IPC: B65D75/58
Filed: 2004-04-12
Abstract: A package having a reclosable pour spout is disclosed, with the package including front and rear package panels which may be joined at respective side edges thereof by inwardly extending side gussets. An upper edge portion of the package is removable, including one of the side gussets, to form a pour spout for dispensing the contents of the package. A fastener strip, which can be detachably connected to itself, extends between confronting inside surfaces of the front and rear package panels, adjacent to the pour spout, whereby the pour spout can be conveniently closed after the package is initially opened. A method of forming the present package is also disclosed.
Patent NZ-545934-A (NZ)
Title: Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient
Inventor: NAGANAWA ATSUSHI
IPC: A61P13/10
Filed: 2004-09-16
Abstract: Disclosed are compounds represented by the general formula (I), wherein each symbol is as defined in the specification. The compounds bind specifically to DP receptors and antagonize the same, but only weakly bind to other prostaglandin receptors, enabling the production of drugs having few side effects. They are useful in preventing and/or treating allergic diseases including allergic nephritis, allergic conjunctivitis, atopic dermatitis, bronchial asthma, food allergies; systemic mast cell disease; systemic mast cell activation disorder; anaphylactic shock; airway contraction; urticaria; eczema; diseases associated with itching including atopic dermatitis; inflammation; chronic obstructive pulmonary disease, ischemic reperfusion injury; cerebrovascular disorders; rheumatoid arthritis; pleuritis and ulcerative colitis.
Patent NZ-550850-A (NZ)
Title: Vertical filling-packaging machine and method of manufacturing packaging bag
Inventor: TSURUTA ORIHIRO
IPC: B65B9/20
Filed: 2005-03-22
Abstract: A vertical filling-packaging machine capable of satisfactorily forming a heat-seal part by heat-sealing, cooling, and cutting a cylindrical film without moving and also manufacturing a variety of packaging bags with different outline shapes. The vertical filling-packaging device comprises a pair of flat part forming rollers disposed oppositely to each other through the cylindrical film (60) and carrying the cylindrical film downward while forming a flat part (60a) on the cylindrical film, a seal mechanism having a heater bar (31) and a heater bar receiver (32) for heat-sealing the flat part in the lateral direction, a cutting mechanism disposed on the lower side of the seal mechanism and having a pair of cooling bars (34a) and (34b) for cooling a heat-sealed lateral seal part (65) and a cutter (35) for cutting the lateral seal part, and a drive mechanism integrally holding the seal mechanism and the cutting mechanism and integrally moving these mechanisms along the carrying direction of the cylindrical film.
Patent NZ-552642-A (NZ)
Title: Barbed sutures
Inventor: LEUNG JEFFERY C
IPC: A61B17/04
Filed: 2003-09-29
Abstract: A barbed suture for connecting tissue. The suture includes an elongated body and a plurality of barbs projecting from the body. Each barb causes the suture to resist movement in an opposite direction from which the barb faces. The disposition of the barbs on the body is a staggered disposition such that the barbed suture has at least two sets of barbs that are offset with respect to each other, each set being aligned longitudinally on the barbed suture, where each barb has a base, and a plane perpendicular to the barbed suture and cutting transversely through the barbed suture and intersecting the base of a barb of the first set will not intersect the base of a barb of the second set.
Patent NZ-555766-A (NZ)
Title: Microbial biocementation
Inventor: KUCHARSKI EDWARD STANISLAW
Filed: 2005-12-20
Abstract: Disclosed is a method of forming a high strength cement in a permeable starting material, the method comprising the step of combining the starting material with the effective amounts of (i) a urease producing micro-organism; (ii) urea; and (iii) calcium ions and wherein the effective amount of the urease producing organism provides a urea hydrolysis rate, under standard conditions, of 0.5-50mM urea hydrolysed.min-1.
Patent NZ-556572-A (NZ)
Title: Power tool
Inventor: GALLAGHER WILLIAM F
Filed: 2007-07-18
Abstract: A power tool is disclosed which comprises: a rotatable wheel spindle having a diametrically truncated portion and a threaded end and an upper flange having a central aperture, arranged to receive the truncated portion of the wheel spindle, where the upper flange includes a top surface and a bottom surface. The top surface has at least one collar and at least one protrusion having two ends extending from the collar toward the central aperture. A power tool component having an aperture arranged to receive the threaded end of the wheel spindle is also provided, where the power tool component being disposed against the bottom surface of the upper flange, and a lower flange threaded on the threaded end of the spindle wheel. This is adapted to press the power tool component against the first flange, wherein the upper flange is adapted to rotate partially with respect to the wheel spindle until a portion of an end of the truncated portion of the wheel spindle abuts a portion of one of the two ends of the protrusion of the first flange.
Patent NZ-562117-A (NZ)
Title: Association between ferroquine and an artemisinine derivative for treating malaria
Inventor: FRAISSE LAURENT
IPC: A61K31/357
Filed: 2006-04-18
Abstract: A combination comprising ferroquine, in free base, salt, hydrate or solvate form, and an artemisinine derivative is disclosed. The disclosure also concerns a pharmaceutical composition comprising ferroquine, in the form of one of its pharmaceutically acceptable salts, ferroquine hydrate or solvate, and at least one artemisinine derivative. The disclosure further concerns the use of such a combination for preparing a medicine for treating or preventing malaria. Finally, the disclosure concerns a kit for treating or preventing malaria.
Patent NZ-568190-A (NZ)
Title: Chimeric compositions and methods for regulating plant gene expression
Inventor: ESPLEY RICHARD
IPC: A01H5/00
Filed: 2008-05-12
Abstract: Provided is a method for producing a chimeric promoter polynucleotide capable of controlling transcription of an operably linked polynucleotide in a plant cell or plant, wherein the method comprises combining: a) at least one sequence motif comprising a sequence with at least 70% identity to a specified sequence from apple or pear, b) another polynucleotide sequence, wherein the chimeric promoter is modulated by a MYB transcription factor. Further provided are corresponding transgenic plants comprising the chimeric promoter having a modified expression of a desired gene.
Patent NZ-569366-A (NZ)
Title: A road structure defining a traffic control intersection
Inventor: GOJ JOZEF
IPC: E01C1/04
Filed: 2006-11-22
Abstract: A road structure defining a traffic control intersection (10) is disclosed. The road structure includes a first road (12), and a second road (14) running crosswise relative to the first road. The first road (12) has markings (13), which define lanes (16) in a first direction. The second road (14) has marking (13) defining lanes (26) in a second direction. Pathways (28), (36), (48) and (56) are provided to enable vehicles travelling along either of the roads to turn into the corresponding lane (leftmost or rightmost lane) in the other road. Two of the pathways (36) and (56) extend over lanes (20) of the second road but are at a different elevation to those lanes so that vehicles on these pathways are not obstructed by vehicles travelling along the lanes (20).
Patent NZ-578530-A (NZ)
Title: Rotatable handle for pullup exercise assembly
Inventor: HAUSER STEPHEN G
IPC: A63B23/12
Filed: 2008-05-26
Abstract: A handle assembly adapted to grasp a bar for exercise. The assembly comprises a J-shaped hook for placement on the bar, a curved portion forming an upper end of the J-hook adapted to grasp the bar to secure the handle assembly to the bar, a rotation assembly, and a handle attached to the rotation assembly. The handle has an inverted V-shaped bracket with a cross piece defining a grip that is connected between ends of the V-bracket. The rotation assembly is arranged between a lower end of the J-hook and the handle, and includes a bearing having a fastener extending there through that is received within the J-hook lower end to attach the J-hook to the handle. The bearing facilitates rotational movement of the handle. A user grasps the handle to place the curved portion of the J-hook over the bar, the handle rotated by the user during exercise, via the bearing, about a vertical axis of the J-hook.
Patent NZ-587206-A (NZ)
Title: A photochemical process for cultivation of microorganisms in a bioreactor
Inventor: MOHR MARTIN
IPC: C12M1/00
Filed: 2009-01-27
Abstract: The disclosure relates to a method and a device for a photochemical, such as photocatalytic and/or photosynthetic process, particularly for the breeding and production or hydrocultivation of preferably phototrophic microorganisms. A reactor, particularly a biosolar reactor (1), comprising at least one reactor element (2), is provided. The reactor element (2) is formed by two perpendicular pipes (3) connected at the bottom. Furthermore, an inlet (4) and an outlet (5) are provided at the upper reactor edge. The meander-shaped conductance of the reaction medium (6) is carried out perpendicularly or inclined at an angle at least once from the top down or in the direction of gravity, and from the bottom up or against the direction of gravity. Both the introduction and removal of the reaction medium (6) into and from the reactor are preferably carried out continuously, without pressure and freely to the atmosphere via the upper reaction medium surface, wherein due to the hydrostatic pressure compensation and levelling a flow of the reaction medium (6) that is stress-free for the microorganisms is produced.
Patent NZ-590646-A (NZ)
Title: Novel compounds useful for the treatment of degenerative and inflammatory diseases
Inventor: MENET CHRISTEL JEANNE MARIE
IPC: A61K31/437
Filed: 2009-07-24
Abstract: Disclosed are substituted [1,2,4]triazolo[1 ,5-a]pyridines of formula VIa useful as Janus tyrosine kinase inhibitors for the treatment of degenerative, inflammatory, proliferative and other diseases. The application also relates to the synthesis of these compounds as well as to their pharmaceutical compositions.
Patent NZ-594854-A (NZ)
Title: Low-molecular polysulfated hyaluronic acid derivative and medicine containing same
Inventor: KAKEHI KAZUAKI
IPC: A61K31/728
Filed: 2010-02-01
Abstract: Disclosed herein is a low-molecular-weight polysulfated hyaluronic acid derivative represented by the following general formula (IA') or (IB), wherein the substituents are as defined within the specification, processes for its preparation, compositions comprising said compounds and uses thereof. Said compounds are useful for the prevention and/or treatment of an allergic disease, in particular pollinosis, allergic rhinitis, allergic conjunctivitis, atopic dermatitis, and asthma.
Patent NZ-595843-A (NZ)
Title: System and method for multi-stream video compression using multiple encoding formats
Inventor: FURMAN SCOTT
IPC: A63F13/12
Filed: 2010-03-17
Abstract: 595843 Disclosed is a computer system for encoding a video stream according to two different formats. The system is comprised of a memory for storing program code and a processor for processing the program code. The code enables the processor to receive user inputs related to an online video game or application. The inputs are received over the internet from a client operated by a user. In response to these inputs, the processor executes program code of the video game or application to render a sequence of video images resulting from execution of the video game or application. The code also causes the processor to encode a plurality of video frames or portions thereof according to a first encoding format (404) which is optimised for video transmission to a client device (415) over a current communication channel. The processor also transmits the plurality of encoded video frames or portions to the client device (415) over the communication channel. Concurrently with these encoding and transmission steps, the processor encodes the plurality of video frames according to a second encoding format which has a higher quality compressed video and/or a relatively lower compression ratio than the first encoding format. The plurality of video frames encoded in the second encoding format is stored on a storage device (405) and made available to the client device (415) and other client devices for playback of the video stream.
Patent NZ-599105-A (NZ)
Title: Methods and compositions for diagnosis and prognosis of renal injury and renal failure
Inventor: ANDERBERG JOSEPH
IPC: G01N33/48
Filed: 2010-09-21
Abstract: Disclosed is a method for evaluating renal status in a subject, said method comprising: - performing a plurality of assays configured to detect both of the proteins tissue metalloproteinase inhibitor-2 (TIMP-2) and tumour necrosis factor receptor superfamily member 11B (TNFRSF11B) in one or more body fluid samples obtained previously from the subject by contacting the body fluid sample(s) with molecules that bind to each of TIMP-2 and TNFRSF11B under conditions sufficient for such binding to occur; - determining a measured concentration of each of TIMP-2 and TNFRSF11B from the amounts of the molecules bound thereto in the body fluid sample(s); - combining the measured concentration of each of TIMP-2 and TNFRSF11B using a function that converts the assay results into a single composite result to thereby provide a combined concentration of TIMP-2 and TNFRSF11B for the subject; - comparing the combined concentration of TIMP-2 and TNFRSF11B for the subject to a threshold concentration; and - correlating the assay results to the renal status of the subject. Also disclosed is a combined use of antibodies or antibody fragments in a method performed ex vivo on one or more body fluid samples obtained previously from a subject in determining a present or future reduced renal function in the subject, wherein the antibodies or antibody fragments bind independently to: (i) TIMP-2 or an epitope thereof; and (ii) TNFRSF11B or an epitope thereof.
Patent NZ-600119-A (NZ)
Title: Process and intermediates for the preparation of 5-biphenyl-4-yl-2-methylpentanoic acid derivatives
Inventor: HOOK DAVID
IPC: A61K31/4015
Filed: 2009-01-16
Abstract: 600119 Disclosed are process for preparing a compound of formula (3) which is 5-Biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one. An example of the process includes reacting a compound of formula 5 (5-Biphenyl-4-ylmethyl-3-hydroxymethyl-pyrrolidin-2-one) to form a compound of formula 12 (such as 5-Biphenyl-4-ylmethyl-3-iodomethyl-pyrrolidin-2-one) and then reducing it to a compound of formula (3). Also disclosed is a compound prepared by the processes.
Patent NZ-601155-A (NZ)
Title: Pyruvamide compounds as inhibitors of dust mite group 1 peptidase allergen and their use
Inventor: ROBINSON CLIVE
IPC: A01N43/00
Filed: 2011-01-21
Abstract: Disclosed here are pyruvamide compounds of the given formula, wherein the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are useful as inhibitors of dust mite group 1 peptidase allergen (for example Der p 1, Der f 1, Eur m 1) and as such are useful in the treatment of diseases and disorders that are mediated by said allergen, such as asthma; rhinitis; allergic conjunctivitis; atopic dermatitis; an allergic condition which is triggered by dust mites; an allergic condition which is triggered by a dust mite Group 1 peptidase allergen; and canine atopy.
Patent NZ-604562-A (NZ)
Title: Method of and system for grinding pyrolysis of particulate carbonaceous feedstock
Inventor: LI CHUN-ZHU
IPC: C10B57/14
Filed: 2011-06-21
Abstract: Disclosed is pyrolysis plant (20) comprises a grinding pyrolyser (22), being a machine or apparatus (rotating cylindrical vessel (26)) in which both particle size reduction and pyrolysis occur simultaneously. Plant (20) also comprises a bin (30) for holding wet particulate biomass feedstock. Chute (32) leads from the bin (30) to a biomass dryer 34 which reduces moisture content of the feedstock to below about 10 % wt. Dried feedstock is conveyed from dryer (34) via line (36) to a dried biomass feedstock hopper (38). Dried feedstock is fed from hopper (38) into a chute (40) which leads to an inlet trunnion (42) of grinding pyrolyser (22). A discharge trunnion (44) of grinding pyrolyser (22) leads to a char holder (60) for collecting char particles and a condensation train (62) for condensing vapour generated by the pyrolysis to produce oil. Said plant is part of a combustion or gasification system having a combustor or gasifier, the plant being arranged to feed products generated by the pyrolysis of the feedstock as a co-firing fuel to the combustor or gasifier. The rotating cylindrical vessel (26) is rotated at a speed below a critical speed (CS) at which biomass feedstock and the grinding media effectively sticks to an inside surface of the vessel due to centrifugal force, wherein the rotational speed of the vessel is between the range 55% to 90% of a critical speed CS. CS = (42.3/D0.5) rpm where D is the internal diameter of the vessel (26) in metres.
Patent NZ-605440-A (NZ)
Title: Solid compositions comprising an hcv inhibitor
Inventor: LIEPOLD BERND
IPC: A61K9/14
Filed: 2011-05-26
Abstract: The disclosure relates to a solid composition, preferably as a solid dispersion comprising: 
(1) a compound, or a pharmaceutically acceptable salt thereof, in an amorphous form, 
(2) a pharmaceutically acceptable hydrophilic polymer, preferably a homopolymer or copolymer of N-vinyl pyrrolidone or copovidone; and 
(3) optionally a pharmaceutically acceptable surfactant, preferably D-alpha-tocopheryl polyethylene glycol 1000 succinate, a combination of D-alpha-tocopheryl polyethylene glycol 1000 succinate and propylene glycol monolaurate or sorbitan mono laurate, 
wherein said compound is selected from the group consisting of: 
dimethyl(2S,2'S)-1,1'-((2S,2'S)-2,2'-(4,4'-((2S,5S)-1-(4-tert-butylphenyl)pyrrolidine-2,5-diyl)bis(4,1-phenylene))bis(azanediyl)bis(oxomethylene )bis(pyrrolidine-2,1-diyl))bis(3-methyl-1-oxobutane-2,1-diyl)dicarbamate (Compound IA), 
methyl[(2S)-1-{(2S)-2-[4-(4-{5-(4-{2-[(2S)-1-{(2S)-2-[(methoxycarbonyl)amino ]-3-methylbutanoyl} pyrrolidin-2-yl]-1H-imidazol-4-yl} phenyl)-1-[6-(piperidin-1-yl)pyridin-3-yl]-1H- 
pyrrol-2-yl} phenyl)-1H-imidazol-2-yl]pyrrolidin-1-yl}-3-methyl-1-oxobutan-2-yl]carbamate (Compound IB), 
methyl {(2S,3R)-1-[(2S)-2-{ 6-[(2R,5R)-1-(4-tert-butylphenyl)-5-(2-{ (2S)-1-[N- 
(methoxycarbonyl)-O-methyl-L-threonyl]pyrrolidin-2-yl}-1H-benzimidazol-6-yl)pyrrolidin-2- 
yl]-1H-benzimidazol-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutan-2-yl}carbamate (Compound 
IC), and 
methyl {(2S)-1-[(2S)-2-{5-[ (2R,5R)-1-[2,5-difluoro-4-(trifluoromethyl)phenyl]-5- {2-[(2S)-1- {(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl} pyrrolidin-2-yl]-1H-benzimidazol- 
5-yl} pyrrolidin-2-yl]-1H-benzimidazol-2-yl} pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl} carbamate (Compound ID).
Patent NZ-610296-A (NZ)
Title: Crystalline form of an inhibitor of mdm2/4 and p53 interaction
Inventor: BERGHAUSEN JOERG
IPC: A61K31/4725
Filed: 2011-11-17
Abstract: Disclosed is a crystalline form of (S)-1-(4-Chloro-phenyl)-7-isopropoxy-6-methoxy-2-(4-{ methyl-[4-(4-methyl-3-oxo-piperazin-1-yl)-trans-cyclohexylmethyl]-amino} -phenyl)-1,4-dihydro-2H-isoquinolin-3-one (see abstract figure) sulfate salt, which may be the bisulfate salt. Also disclosed are pharmaceutical compositions containing this crystalline form and methods of treatment of a disease or disorder associated with the activity of MDM2 and/or MDM4. These can include tumours and cancers.
Patent NZ-622847-A (NZ)
Title: [1,2,3]triazolo[4,5-d]pyrimidine derivatives as agonists of the cannabinoid receptor 2 agonists
Inventor: ROGERS-EVANS MARK
IPC: C07D487/04
Filed: 2012-11-22
Abstract: The disclosure relates to a [1,2,3]triazolo[4,5-D]pyrimidine derivatives of formula (I) as agonist of the cannabinoid receptor 2. An example of the derivative is 5-tert-butyl-2-(2-chloro-benzyl)-7-morpholin-4-yl-2H-[1,2,3]triazolo[4,5-d]pyrimidine.
Patent NZ-623327-A (NZ)
Title: Carton with handle
Inventor: KASTANEK RAYMOND S
IPC: B65D71/32
Filed: 2012-10-17
Abstract: A blank for a cardboard container for holding bottles is described. The container uses folding reinforcing flaps to add overlapping layers to the handle portions for reinforcement when the container is lifted. The container (5) is made from a four panelled blank, with side flaps (39, 45), top flaps (49) and bottom flaps (35, Figure 1). The side flaps have reinforcing flaps (121, 115) which fold over when the top flap (49) is closed, causing both to overlap with the second reinforcing portion (113), thus reinforcing the handle (81).
Patent NZ-624527-A (NZ)
Title: Waterborne antifouling coating composition
Inventor: DUNFORD GRAEME
IPC: C09D5/16
Filed: 2012-09-03
Abstract: Disclosed is a waterborne antifouling coating composition comprising (i) a binder polymer,(ii) a pigment and (iii) no biocide or a biocide selected from (a) a copper biocide or a copper biocide in combination with at least one or more co-biocide(s), or(b)a copper-free biocide or a copper-free biocidein combination with at least one or moreco-biocide(s), with the proviso that the biocide is not a copper biocide in combination with zinc pyrithione, and wherein the pigment volume concentration of the waterborne antifouling coating composition is greater than 80% and less than 95%.