baber/WOPTO huggingface dataset:
Patent NZ-214930-A (NZ)
Title: Solution polymerisation of ethylene
Inventor: ZBORIL V G
IPC: C08F2/42
Filed: 1986-01-24
Abstract: A solution polymerization process for the pre-paration of high molecular weight homopolymers of ethylene and copolymers of ethylene and C3 - C12 alpha-olefins comprises feeding monomer(s), coordination catalyst and inert hydrocarbon solvent to a reactor, polymerizing the monomers at a temperature of up to 320 DEG C and a pressure of less than 25 MPa, and deactivating the catalyst in the solution so obtained. The catlyst is deactivated by sequentially admixing therewith (a) a minor amount of a first deactivator, (b) a solution of a salt of an alkaline earth metal or zinc and an aliphatic mono-carboxylic acid dissolved in hydrocarbon solvent, and (c) an organosilicon compound. The solution of (b) and the compound of (c) may be combined. The first deactivator may be water, a nitrogenous base or carbon dioxide or the like. The organosilicon compound is of the formula SiR min n (OR) sec )4-n where R min  and R sec  are alkyl or cycloalkyl and n is 0-3. The hydrocarbon solvent and other volatile matter are then separated from the resultant solution and a composition comprising said high molecular weight polymer is recovered.
Patent NZ-215414-A (NZ)
Title: Cyclosporins as pharmaceuticals
Inventor: SEEBACH DIETER
IPC: A61P33/10
Filed: 1986-03-10
Abstract: Cyclosporins e.g. of formula IIin whichX is -MeBmt- or -dihydro-MeBmt- andY is -aAbu-, Thr-, -Val- or -Nva-, wherein the residue at the 3-position, i.e. the residue Z in formula II, is an optically active, a-N-methylated a-aminoacid residue of the (D)-configuration, possess pharmaceutical, in particular immunosuppressive, anti-inflammatory and anti-parasitic activity. Intermediate cyclosporin poly-anions having a de-protonated sarcosyl residue at the 3-position, e.g. polyanions of cyclosporins of formula II above wherein X and Y have the meanings given above and Z is -Sar<sub>-</sub>, in which the said residue Z is de-protonated, are also novel and part of the invention.
Patent NZ-222597-A (NZ)
Title: Process for the production of pure dimethyl ether
Inventor: DORNHAGEN HORST
IPC: C07C41/42
Filed: 1987-11-18
Abstract: Pure dimethyl ether is prepared by catalytic dehydration of methanol over a  gamma -Al2O3 catalyst which preferably contains small amounts of SiO2 and purification of the dehydration product by addition thereof to a distillation column to obtain pure dimethyl ether on certain plates of this column and taking off the pure dimethyl ether and impurities above certain plates of the same column.
Patent NZ-223477-A (NZ)
Title: Tetrazole-substituted naphthalene carboxamide derivatives and anti-inflammatory compositions
Inventor: CONNOR D T
IPC: C07D257/06
Filed: 1988-02-10
Abstract: Novel naphthalene derivatives of the formula (I): <CHEM> having antiallergy and antiinflammatory activity. E
Patent NZ-226433-A (NZ)
Title: 14-aminoandrostane 17-carboxylic acid ester derivatives
Inventor: JARREAU FRANCOIS-XAVIER
IPC: C07J41/00
Filed: 1988-10-03
Abstract: The invention relates to androstane-17-carboxylic acid esters, represented by general formula (I):   <IMAGE>   wherein R1 represents a lower alkyl group containing 1 to 4 carbon atoms, a lower alkyl group containing 2 to 4 carbon atoms substituted by an amino group, or an aralkyl group from 6 to 12 carbon atoms, R2 and R3, which may be the same or different, represent a hydrogen atom or a lower alkyl group containing 1 to 4 carbon atoms, R4 represents a hydrogen atom, a hydroxy group or an acetoxy group, R5 represents a hydroxy or acetoxy group, or R4 and R5 represent together a divalent alkylenedioxy group, R6 represents a hydroxy group, a methoxy group, or an acetoxy group, R7 represents a methyl group or a hydroxymethyl group, R8 represents an hydrogen atom or a hydroxy group and <IMAGE>  represents either a   <IMAGE>  group or a   <IMAGE>  carbon atom having the double linkage in the 4- or 5-position of the steroid nucleus. Such esters are prepared by coupling reaction of the corresponding 14-azido-derivatives with a sugar, followed by a reduction. Application in therapy, especially in the treatment of heart failure.
Patent NZ-226693-A (NZ)
Title: N-alkylphenyl benzamide derivatives, preparation thereof and fungicidal compositions
Inventor: ARNOLD WENDELL RAY
IPC: C07C257/00
Filed: 1988-10-25
Abstract: Compounds of the formula (I): <CHEM>  wherein:  X = O, S, or NOH;  R<1> is H or CH3;  n = 1, 2, or 3; R<2>, R<3>, and R<4> are as defined in one of the following paragraphs     a) R<2> and R<3> are independently Cl or Br, and R<4> is H;   b) R<2>, R<3>, and R<4> are independently Cl or Br;   c) R<2> is F, R<3> is Cl, and R<4> is H; or   d) R<2> and R<3> are CH3 or C2H5, and R<4> is H; R<5>, R<6>, and R<7> are as defined in one of the following paragraphs   a) one of R<6> and R<7> is CH3, R<5> and the other of R<6> and R<7> is H;   b) R<5> and R<6> are H; and R<7> is F, Cl, or Br;   c) R<5> and R<7> are independently F, Cl, or Br and R<6> is H;   d) R<5> and R<6> are independently F, Cl, or Br, and R<7> is H;   e) R<6> and R<7> are independently F, Cl, or Br, and R<5> is H; or   f) R<6> is phenoxy and R<5> and R<7> are H, are useful fungicides, either alone or in combination with other fungicides.
Patent NZ-228399-A (NZ)
Title: Composition comprising a carboxylic acid containing at least 3 carbon atoms and an organic sulphur-containing acid or salt thereof
Inventor: BATH COLIN
IPC: C08K5/41
Filed: 1989-03-20
Abstract: A composition comprises a carboxylic acid compound which contains at least three carbon atoms together with an organic sulphur-containing acid or salt of such an acid. The carboxylic acid may be an aliphatic diacid such as succinic acid. The sulphur-containing acid may be a sulphonic or sulphuric acid derivative such as the sodium salt of an alkyl sulphonic acid or of sulpho-succinic acid or of a carboxylic acid ester derivative of sulpho-succinic acid. The composition may be incorporated into an olefin polymer. The composition may be obtained by conventional powder blending or, for a polymer composition, melt blending techniques. Preferred polymer compositions have an increased clarity and a reduced level of haze compared to the polymer alone or the polymer containing only the carboxylic acid.
Patent NZ-241592-A (NZ)
Title: 4-[(2-benzothiazolyl)methylamino]-alpha-[(3,4-difluorophenoxy)methyl] -1-piperidine ethanol and pharmaceutical compositions thereof
Inventor: STOKBROEKX RAYMOND ANTOINE
IPC: C07D303/23
Filed: 1992-02-11
Abstract: A compound of formula <CHEM> the racemic mixture, the (S)-form and the acid addition salts thereof, said compound having anti-stroke properties. Pharmaceutical compositions containing this compound as active ingredient and a method of preparing said compound and pharmaceutical compositions.
Patent NZ-243604-A (NZ)
Title: Snap hinge dispensing bottle closure: aligns a thumb recess on closure with bottle front
Inventor: LOHRMAN RICHARD D
IPC: B65D47/08
Filed: 1992-07-17
Abstract: This invention is directed towards improvements in snap hinge dispensing closures for molded plastic bottles. In particular, snap hinge closures of single walled construction are provided with means for positively aligning with the front of the bottle, and a relatively deeper thumb recess for facilitating lifting of a snap hinge closure lid. Means are also disclosed to prevent reverse rotation of the closure once positive alignment is achieved. Other disclosed features include a plug to prevent leakage of the bottle contents and means for preventing axial pivoting of the closure.
Patent NZ-249162-A (NZ)
Title: Preparation of taxane derivatives from a protected baccatin iii and a 2-hydroxy-3-amino-3-aryl-propanoic acid at a temperature between -10 and 60 deg c
Inventor: FOUQUE ELIE
IPC: C07D305/14
Filed: 1993-02-04
Abstract: This invention relates to a method for preparing taxane derivatives of general formula (I)by esterification at a temperature between -10 and 60° C. of a derivative of baccatine III or 10-deacetyl baccatine III of general formula (II)by means of an acid of general formula (III),followed by replacement of the protective groupings G1, G2 and R2 of the resulting product by hydrogen atoms. In formulae (I), (II) or (III), Ar stands for an aryl radical; R stands for hydrogen or acetyl; R1 is benzoyl or ter.butoxycarbonyl; G1 is a hydroxy function protective grouping, G2 stands for the acetyl radical or a hydroxy function protective grouping, and R2 stands for a hydroxy function protective grouping.
Patent NZ-254604-A (NZ)
Title: Quinuclidine derivative and pharmaceutical compositions thereof
Inventor: ITO FUMITAKA
IPC: A61P25/28
Filed: 1993-07-19
Abstract: PCT No. PCT/US93/06624 Sec. 371 Date Jun. 19, 1995 Sec. 102(e) Date Jun. 19, 1995 PCT Filed Jul. 19, 1993 PCT Pub. No. WO94/11368 PCT Pub. Date May 26, 1994This invention relates to the quinuclidine derivative (2S, 3S)-N-(5-n-propyl-2-methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine and its pharmaceutically acceptable salts. These compounds are substance P antagonists and are useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain.
Patent NZ-264218-A (NZ)
Title: Storage stable aqueous composition of alpha-interferon
Inventor: LOWTHER NICHOLAS
IPC: A61K47/26
Filed: 1994-08-11
Abstract: The present invention provides a stable aqueous solution of hybrid alpha -Interferon which contains as the stabiliser a buffer at a pH of from 3.0 to 5.0.
Patent NZ-267032-A (NZ)
Title: Security document with embossed image on a transparent portion for differing visibility depending upon viewing angle
Inventor: JACKSON WAYNE KEVIN
IPC: B42D25/29
Filed: 1994-06-06
Abstract: PCT No. PCT/AU94/00302 Sec. 371 Date Dec. 7, 1995 Sec. 102(e) Date Dec. 7, 1995 PCT Filed Jun. 6, 1994 PCT Pub. No. WO94/29119 PCT Pub. Date Dec. 22, 1994A security document or token such as a banknote (40) is provided which has a transparent portion (42) of plastics material which includes a security device (50). The region (44) surrounding the transparent portion (42) and preferably all the remaining part of the banknote (40) is printed with indicia. The security device (50) includes regions (52, 54, 56 and 58) of embossed lines extending at different angles to each other defining different shapes that are visible to a greater or lesser extent upon transmission and reflection of light as the note is tilted, rotated or viewed from different angles relative to a light source. The embossed lines in some of the regions (52 and 54) are finer than coarser and deeper and more widely spaced lines in the other regions (56 and 58). The coarser, deeper lines are of such a thickness and width to be detected by touch in addition to being visible by the naked eye. There is also provided a method of and apparatus for producing a banknote with a security device in accordance with the invention in which the transparent portion of the note is embossed during an intaglio printing process.
Patent NZ-278807-A (NZ)
Title: Pliers; locking type with axial clamping action
Inventor: DAHL RAYMOND
IPC: B25B7/02
Filed: 1995-01-10
Abstract: A pair of locking pliers includes a body having a fixed jaw that supports a fixed extension. A movable jaw is pivotably mounted to the body by a hinge pin, and the movable jaw includes a movable extension. An operating lever is pivotably mounted to the movable jaw to close the movable jaw, and the movable jaw is shaped such that the movable extension slides along the fixed extension as the movable jaw is pivoted closed with the operating lever in order to provide an axial clamping action.
Patent NZ-284357-A (NZ)
Title: N6-heterocyclic-substituted adenosine or N6-heterocyclic-substituted carbocyclic adenosines derivatives for use in treating myocardial ischemia or hypertension
Inventor: SPADA ALFRED P
IPC: A61K31/7042
Filed: 1995-04-19
Abstract: Use of a compound of the Formula (I) for the manufacture of medicaments for prophylactic treatment of ischemic injury or myocardial infarct size as a consequence of to myocardial ischemia. Wherein, K is N, N?O or CH; Q is CH2 or O; T is R1-N(R2)-C(O)- or R3O-CH2; X is a straight or branched chain alkylene, cycloalkylene or cycloalkenylene group; Y is NR4, O or S; a=0 or 1; Z is of the Formula (II) and (III); wherein Z1 is N, CR5, (CH)m-CR5 or (CH)m-N, m being 1 or 2; Z2 is N, NR6, O or S, n being 0 or 1; R1, R2, R3, R4, R5 and R6 are independently H, alkyl, aryl or heterocyclyl; Ra and Rb are independently H, OH, alkyl, hydroxyalkyl, alkyl mercaptyl, thioalkyl, alkoxy, alkyoxyalkyl, amino, alkyl amino, carboxyl, acyl, halogen, carbamoyl, alkyl carbamoyl, aryl or heterocyclyl; and; R' and R" are independently hydrogen, alkyl, aralkyl, carbamoyl, alkyl carbamoyl, dialkylcarbamoyl, acyl, alkoxycarbonyl, aralkoxycarbonyl, aryloxycarbonyl, or R' and R" together may form Formula (IV), (V), (VI), (VII) where Rc is hydrogen or alkyl, where Rd and Re are independently hydrogen, alkyl, or together with the carbon atom to which they are attached may form a 1,1-cycloalkyl group; provided that when X is straight chain alkylene and Q is oxygen, then Z represents a heterocyclyl including at least two heteroatoms.
Patent NZ-304696-A (NZ)
Title: Encapsulation of anti-cholesterol nutritional product with zein
Inventor: BEHR STEPHEN RICHARD
IPC: A23L1/308
Filed: 1996-03-21
Abstract: A nutritional product having a solid matrix containing protein, fat and carbohydrate has disposed therein particles of dietary fiber encapsulated in zein. The preferred dietary fiber is guar. Such a nutritional product may be used for reducing the serum cholesterol in a mammal.
Patent NZ-312081-A (NZ)
Title: A two stage hormonal contraception (fertility control) in at least 30 daily doses containing an oestrogen (estrogen) preparation and a kit therefore.
Inventor: SCHMIDT-GOLLWITZER KARIN
IPC: A61K31/585
Filed: 1996-06-27
Abstract: The present invention describes a two-stage pharmaceutical combined preparation for hormonal contraception containing at least 30 daily unit doses, which preparation, in its first stage, comprises as hormonal active ingredient a combination of an oestrogen preparation and, in a dose that is at least sufficient to inhibit ovulation, a gestagen preparation, in single stage form and, in the second stage comprises as hormonal active ingredient an oestrogen preparation only, wherein the first stage comprises a minimum of 25 and a maximum of 77 daily discrete or continuous unit doses and the second stage comprises 5, 6 or 7 daily discrete or continuous unit doses, and wherein the total number of daily units is equal to the total number of days of the desired cycle of a minimum of 30 and a maximum of 84 days. This combined preparation, in the form of a monthly pack, which is used for female fertility control, permits as low as possible an oestrogen content in each individual unit dose and also has a low total hormone content per cycle of administration, with high contraceptive reliability, low incidence of follicle development, and satisfactory cycle control with reliable avoidance of intermediate bleeding as well as undesired side effects.
Patent NZ-326578-A (NZ)
Title: Substituted benzamides as pde iii, pde iv and tnf inhibitors
Inventor: MULLER GEORGE W
IPC: A61P35/00
Filed: 1996-12-24
Abstract: 1. Use of a compound of the formula <CHEM> in which:  one of R<1> and R<2> is R<3>-X and the other is hydrogen, nitro, cyano, trifluoromethyl, carbo(lower)alkoxy, acetyl, carbamoyl, acetoxy, carboxy, hydroxy, amino, lower alkyl, alkylamino, lower alkoxy, halo, HF2CO, F3CO or R<3>-X-; R<3> is monocycloalkyl, bicycloalkyl or benzocycloalkyl of up to 18 carbon atoms, tetrahydropyran or tetrahydrofuran; X is a carbon-carbon bond, -CH2-, -O- or -N=; R<5> is (i) o-phenylene, unsubstituted or substituted with 1 or more substituents each selected independently from nitro, cyano, halo, trifluoromethyl, carbo(lower)alkoxy, acetyl, or carbamoyl, unsubstituted or substituted with lower alkyl, acetoxy, carboxy, hydroxy, amino, lower alkylamino, lower acylamino, aminoalkyl, or lower alkoxy; (ii) the vicinally divalent residue of pyridine, pyrrolidine, imidizole, naphthalene, or thiophene, wherein the divalent bonds are on vicinal ring carbon atoms; (iii) a vicinally divalent cycloalkyl or cycloalkenyl of 4-10 carbon atoms, unsubstituted or substituted with one or more substituents each selected independently from the group consisting of nitro, cyano, halo, trifluoromethyl, carbo(lower)alkoxy, acetyl, carbamoyl, acetoxy, carboxy, hydroxy, amino, lower alkylamino, lower alkyl, lower alkoxy, or phenyl; (iv) vinylene di-substituted with lower alkyl; or (v) ethylene, unsubstituted or monosubstituted or disubstituted with lower alkyl; R<6> is -CO-, -CH2- or -CH2CO-; Y is -COZ, -CN, -OR<8>, lower alkyl or aryl, Z is -NH2, -OH, -NHR, -R<9>, or -OR<9>; R<8> is hydrogen or lower alkyl; R<9> is lower alkyl or benzyl, and n has a value of 0, 1, 2, or 3,  wherein the term "lower" denotes from 1 to 6 carbon atoms, for the manufacture of a medicament for treating cancer.
Patent NZ-329319-A (NZ)
Title: Medical infusion pump
Inventor: MEINZER RANDOLPH R
IPC: A61M5/00
Filed: 1997-01-23
Abstract: The present invention provides an infusion pump having a main body portion. The main body portion includes a display area for displaying user interface information. At least one pump module is provided which is removably secured to the main body portion and adapted to receive an IV tube. The pump module includes means for applying pumping action to the IV tube. A microprocessor is contained in the main body portion for generating user interface information on the display area. The infusion pump also comprises means for sensing tube restrictions and included in the user interface information is a graphical representation of the degree to which the tube is restricted. <IMAGE>
Patent NZ-331078-A (NZ)
Title: A claw for a milking machine
Inventor: SANDGREN KARL-OLOF
IPC: A01J5/04
Filed: 1997-02-04
Abstract: A claw, for a milking machine, comprises a housing 1 having a first portion 2 and a second portion 3.  At least one inlet member 8, 9 on portion 3 connects the inner space of housing 1 to a teatcup of the milking machine.  An outlet member 6 on portion 2 connects the inner space of housing 1 to a milk collecting member of the milking machine via a conduit member and a distributing member 25 comprising at least one inlet pipe 26 directed in essentially the same direction as outlet member 6.  Portion 2 is rotatable in relation to portion 3 to such a position that no torsional force will be applied to the claw via the conduit member when the claw is attached to an animal to be milked.
Patent NZ-500693-A (NZ)
Title: Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
Inventor: KHOSLA CHAITAN
IPC: A61P31/04
Filed: 1998-04-30
Abstract: Combinatorial libraries of polyketides that can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin are disclosed. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, preparation of polyketides and antibiotics by using this method is also disclosed.
Patent NZ-503496-A (NZ)
Title: Dispensing apparatus for dispensing fluid with helical abutment to control adjustment of stroke
Inventor: MAIN JOHN ROBERT
IPC: G01F11/02
Filed: 2000-03-21
Abstract: A dispensing apparatus for a liquid which relies on moulded components capable of being interchanged to provide, in addition to incremental adjustment within a range of dosages allowed by stroke limiting rotational adjustment of the relativity of escarpment and abutment members, the change of one or both the spread of the dosage range and at least one limit of the range.
Patent NZ-507405-A (NZ)
Title: Method for the treatment of fertility disorders
Inventor: ENGEL JURGEN
IPC: A61K35/52
Filed: 1999-03-29
Abstract: A method of therapeutic management of infertility by intrauterine insemination, consisting the steps: a) the dose-dependent suppression of endogenous gonadotropins, with a LH-RH antagonist allowing the maintenance of physiological oestrogen levels; b) exogenous stimulation of the ovarian follicle growth; c) ovulation induction with HCG, native LHRH, LHRH agonists or recombinant LH; d) intrauterine insemination by sperm injection.
Patent NZ-509700-A (NZ)
Title: Additive composition comprising starch and polyamide epichlorhydrin resin (PAAE) and it's use for increasing the strength of the wet web in paper making
Inventor: LUUKKONEN KARI
IPC: D21H17/00
Filed: 1999-07-07
Abstract: Additive composition for paper making to be added to the pulp prior to web formation, wherein the composition as its basic component contains a component which is made from starch, which has been thinned to a viscosity level of 10 to 400 (5%, 60°C), and has been cationized by solution cationized using a quarternary nitrogen compound to a charge of <4 mEq/g, and at least one additional component, which are 1) a starch-based polymer dispersion which contains starch and a monomeric graft copolymer which comprises, calculated from the dry matter content of the product; a) 5 to 40% of starch, cationized to have a degree of substitution of 0.01 to 1 and an intrinsic velocity of > 1.0 dl/g; b) 60 to 95% of a monomer mixture containing at least one vinyl monomer and having a film formation temperature of 0 to 70°C of a polymer formed from said monomer mixture and water; 2) polyamide epichlorhydrin resin (PAAE).
Patent NZ-509722-A (NZ)
Title: Incorporation of exogenous lactic bacteria into the oral microflora
Inventor: NEESER JEAN-RICHARD
IPC: A23L33/00
Filed: 2001-01-11
Abstract: The use of lactic bacteria that is not part of the resident microflora of the mouth, and that is low acidifying (pH of 5.5-5.7) and is capable of adhering directly to the pellicle of the teeth for the preparation of a composition intended for the prophylaxis or the treatment of dental caries, dental plaque and periodontal infection.
Patent NZ-513684-A (NZ)
Title: A method of enhancing cheese yield by adding a partial hydrolysate of the milk whey protein to the milk material, subjecting the resulting mixture to a milk coagulating enzyme, and separating the cheese curd from the whey
Inventor: KUMAZAWA YOSHIYUKI
IPC: A23C19/05
Filed: 2001-08-21
Abstract: A cheese yield enhancing method in the manufacturing of cheese whose process comprises separating a cheese curd from whey after a milk coagulating treatment of a material milk by a milk coagulating enzyme comprises: a) adding/mixing a protein decomposing enzyme treated material of a milk whey protein (a partial hydrolysate of the milk whey protein) to the material milk. b) subjecting the resulting mixture to the milk coagulating treatment by the milk coagulating enzyme. The method may also comprise the step of allowing transglutaminase to act on the partial hydrolysate of milk whey protein/material milk mixture before subjecting the mixture to the milk coagulating treatment.