baber/WOPTO huggingface dataset:
Patent CA-2432303-C (CA)
Title: Pyrazole compounds useful as protein kinase inhibitors
Inventor: BEBBINGTON DAVID
IPC: A61K31/541
Filed: 2001-12-19
Granted: 2010-04-13
Abstract: This invention describes novel pyrazole compounds of formula (IV): wherein Z1 or Z2 is nitrogen, Q is -S-, -O-, -N(R4)-, -C(R6')2-, 1,2-cyclopropanediyl, 1,2-cyclobutanediyl, or 1,3-cyclobutanediyl, and R1 is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx and Ry are independently selected from T- R3 or L-Z-R3, or Rx and Ry are taken together with their intervening atoms to form a fused, unsaturated or partially unsaturated, 5-7 membered ring having 0-3 heteroatoms; and R2 and R2' are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
Patent CA-2436993-C (CA)
Title: Aero-engine exhaust jet noise reduction assembly
Inventor: TSE MAN-CHUN
IPC: F02K1/48
Filed: 2001-12-13
Granted: 2009-09-15
Abstract: A gas turbine engine (10) of a fan bypass type includes an exhaust shroud (60) having a perforated tubular wall (62) extending between a forward end (64) and an aft end (66). The exhaust shroud is adapted to be affixed to a gas turbine engine exhaust for discharging engine exhaust gases without substantial blockage thereto. The perforations (68) formed in the shroud wall communicate the regions at both sides of the shroud wall to pass fluid flow across the perforated shroud wall so that the mixing of the engine exhaust gases with a surrounding fluid flow is enhanced. The mixing of the engine exhaust gases with the surrounding fluid flow is further enhanced by a trailing edge (70) of the exhaust shroud. The trailing edge is deviated from a straight line in a circumferential direction of the tubular wall to effectively increase the peripheral length of the mixing boundary. Thus, the jet noise contribution volume of the engine exhaust gases is effectively reduced, thereby significantly reducing the aero-engine jet noise. The exhaust shroud for enhancing the mixing of engine exhaust gases with the surrounding fluid flow is applicable to both short and long cowl nacelle gas turbine engines and is simple and economical to manufacture and maintain.
Patent CA-2438904-C (CA)
Title: Preparation rapide de matrices de cellules souches destinees a etre utilisees pour le traitement et la reparation de tissus et d'organes
Inventor: CHANCELLOR MICHAEL B
IPC: A61K35/12
Filed: 2002-02-22
Granted: 2012-09-04
Abstract: La présente invention concerne une méthode rapide de préparation de cellules souches et de compositions de matrice acceptables d'un point de vue physiologique, destinées à être utilisées dans la réparation de tissus et d'organes. Comparées aux matières de génie tissulaire déjà existantes, les compositions de matrice de cellules souches de la présente invention ne nécessitent pas d'incubation ou de culture de longue durée in vitro avant utilisation dans des applications in vivo. Lesdites cellules souches peuvent provenir de nombreuses sources et peuvent être homogènes, hétérogènes, autologues, et/ou allogéniques dans la matière de matrice. Lesdites compositions de matrice de cellules souches selon l'invention, permettent d'obtenir un point de service utilitaire pour le praticien, les cellules souches et le support pouvant être combinés peu avant l'utilisation, atténuant ainsi les longues et coûteuses procédures de fabrication. De plus, les cellules souches confèrent des propriétés structurales uniques à la composition de matrice, qui améliorent le résultat clinique et la guérison après utilisation. L'utilisation de cellules souches obtenues à partir du muscle assure une certaine contractilité à la composition de matrice.
Patent CA-2443388-C (CA)
Title: Filtering body for filtering particles contained in an internal combustion engine exhaust gases
Inventor: BARDON SEBASTIEN
IPC: B01D46/42
Filed: 2002-04-04
Granted: 2009-09-15
Abstract: The invention concerns a filtering body (7) consisting of a plurality of adjacent channels through the walls of which said exhaust gases are filtered.  It comprises first (12 to 23) and second (8 to 11) filtering zones, the surface filtering the gases, relative to the unit area of the gas intake of said body (7), being different in the first (12 to 23) and second (8 to 11) zones. The invention is applicable to a diesel engine.
Patent CA-2445377-C (CA)
Title: Finely distributed stabilising composition for polymers containing halogen
Inventor: FOKKEN STEFAN
IPC: C08K3/18
Filed: 2002-05-16
Granted: 2010-07-06
Abstract: The invention relates to a stabilizing composition for polymers containing halogen, said composition containing a salt of an oxyacid that contains halogen and an inorganic or organic acid. The invention also relates to a method for the production of said stabilizing compositions and to polymers containing halogen which contain said stabilizing compositions.
Patent CA-2446132-C (CA)
Inventor: WEN JIANYE
IPC: B32B7/10
Filed: 2002-06-11
Granted: 2007-08-14
Abstract: An exemplary primer/membrane package system comprises (a) a membrane (16) comprising a carrier sheet (18) and a pressure-sensitive adhesive (20) thereon; and (b) an aqueous dispersion primer composition (12) operative to promote adhesion between a construction surface (10) and the membrane. The primer composition comprises at least two of an acetate, maleate, and acrylate, and has a viscosity of 200-2000 cp and more preferably 400-800 cp.
Patent CA-2450527-C (CA)
Inventor: MCGLOTHLAN J KIRK
IPC: B41J2/055
Filed: 2003-11-25
Granted: 2008-10-21
Abstract: A drop emitting device that includes a fluid channel layer, a diaphragm layer having a laser ablated bonding region, and a plurality of electrical components attached to the laser ablated bonding region.
Patent CA-2452193-C (CA)
Inventor: ANDERSON BRENT G
IPC: B65D81/20
Filed: 2002-05-29
Granted: 2006-11-28
Abstract: La présente invention concerne un sac de stockage (10) souple dans lequel on peut faire le vide, qui possède une partie stockage (12), une fermeture (14) étanche à l'air et une valve monodirectionnelle. Cette valve comprend une bande (52) prise en sandwich entre la feuille du dessus et la feuille du dessous (40, 42) utilisées pour fabriquer ce sac (10). Cette bande (52) est liée le long des bords des feuilles du dessus et du dessous de façon à former un seul passage se prolongeant de la partie stockage à l'extérieur du sac.
Patent CA-2452567-C (CA)
Inventor: SKOVMAND OLE
IPC: A01M29/34
Filed: 2002-07-05
Granted: 2009-12-22
Abstract: A fencing for preventing insects to enter an open air area comprising a substantially upright structure with a height suitable to prevent low flying insects to enter said open air area. The structure of the fencing is impregnated with an insecticide.
Patent CA-2460981-C (CA)
Inventor: PREININGER CLAUDIA
IPC: C09D161/06
Filed: 2002-09-24
Granted: 2011-04-05
Abstract: L'invention concerne un support fixe pour l'immobilisation de biomolécules, lequel est recouvert, au moins par endroits, d'un polymère, caractérisé en ce que le polymère est une résine époxy d'une fonctionnalité comprise entre 4 et 15. L'invention concerne en outre un procédé permettant sa fabrication.
Patent CA-2462387-C (CA)
Title: Rigid, dimensionally stable polyurethane foams and a process for the production of such foams in which the foam pressure is reduced
Inventor: INGOLD KERRY A
IPC: C08J9/14
Filed: 2004-03-29
Granted: 2011-11-15
Abstract: Rigid foams are made by reacting a polyisocyanate with an isocyanate-reactive composition which includes at least one isocyanate-reactive compound, preferably, an amine-initiated polyol and more preferably, an amine-initiated polyether polyol and a second, different polyol in the presence of a blowing agent composition which includes water and a catalyst composition which includes two different blowing catalysts, preferably, pentamethyldiethylenetriamine and bis(2- dimethylamino-ethyl)ether.
Patent CA-2463050-C (CA)
Inventor: MOERDIJK ARD-JAN
IPC: H04W4/00
Filed: 2002-08-29
Granted: 2012-03-13
Abstract: La présente invention concerne un procédé de transfert entre des premier et second programme de développement d'application de service dans une architecture de systèmes ouverts. Ledit procédé consiste à enregistrer un second programme de développement d'application de service dans un cadre d'architecture de systèmes ouverts. Les propriétés du second programme de développement d'application de service enregistré sont comparées aux propriétés d'au moins un des premier programmes de développement d'application de service qui détermine si le second programme de développement d'application de service est rétro-compatible avec le premier programme de développement d'application de service. Des informations concernant le fait que le second programme de développement d'application de service est rétro-compatible ou pas avec le premier programme de développement d'application de service sont ensuite envoyées vers une application qui utilise le premier programme de développement d'application de service. Des informations supplémentaires pouvant être envoyées à l'application dans le même message sont, par exemple, le fait que le second programme de développement d'application de service rend désuet un premier programme de développement d'application de service, que l'application peut déjà commencer à utiliser une stratégie de transfert et des références à des interfaces présentes sur le second programme de développement d'application de service.
Patent CA-2463377-C (CA)
Title: Materiau semi-conducteur organique dope et son procede de production
Inventor: WERNER ANSGAR
IPC: H01L51/00
Filed: 2003-02-20
Granted: 2015-01-06
Abstract: L'invention concerne un matériau semi-conducteur organique dopé présentant une densité accrue des porteurs de charge et une mobilité réelle des porteurs de charge et obtenu par dopage d'un matériau semi-conducteur organique avec un composé chimique constitué d'un ou de plusieurs groupes moléculaires organiques A et d'au moins un autre constituant B. L'effet de dopage désiré est obtenu après séparation d'au moins un groupe moléculaire organique A du composé chimique au moyen d'au moins un groupe moléculaire organique A ou du produit d'une réaction d'au moins un groupe moléculaire A avec un autre atome ou une autre molécule. L'invention concerne également un procédé pour la production de ce matériau semi-conducteur organique dopé.
Patent CA-2464375-C (CA)
Inventor: NAGARAJ BANGALORE ASWATHA
IPC: C23C28/00
Filed: 2004-04-15
Granted: 2010-07-20
Abstract: A method applying a thermal barrier coating (150) to a metal substrate (100), or for repairing a thermal barrier coating (128) previously applied by physical vapor deposition to an underlying aluminide diffusion coating (106) that overlays the metal substrate (106). The aluminide diffusion coating (106) is treated to make it more receptive to adherence of a plasma spray-applied overlay alloy bond coat layer (142). An overlay alloy bond coat material is then plasma sprayed on the treated aluminide diffusion coating (136) to form an overlay alloy bond coat layer (142). A ceramic thermal barrier coating material is plasma sprayed on the overlay alloy bond coat layer (142) to form the thermal barrier coating (150). In the repair embodiment of this method, the physical vapor deposition-applied thermal barrier coating (128) is initially removed from the underlying aluminide diffusion coating (106).
Patent CA-2465221-C (CA)
Title: Localized read-only storage device for distributing files over a network
Inventor: CHUNG KEICY K
IPC: G06F17/30
Filed: 2002-10-07
Granted: 2010-05-11
Abstract: A Read-only storage device (202) having network interface (307), a system including the device, and a method of distributing files over a network. The storage device comprises a processor .(304) communicably connected to a computer interface, a network interface (307), and a storage means (308). The processor is communicates with a computer and a file server (314, 315, 316) through the computer interface and the network interface, respectively. The computer may request a file from the processor and the processor responds by either (1) providing the requested file to the computer on a read-only basis if the file is cached on the storage means, (2) obtains the file from the file server if the file is available from the file server, caches the obtained file on the storage means, and provides the obtained file to the computer on a read-only basis, or (3) returns a file unavailable notice to the computer.
Patent CA-2471281-C (CA)
Title: Method for producing polymethacrylimide foams
Inventor: STEIN PETER
IPC: B29C44/08
Filed: 2002-08-01
Granted: 2010-02-23
Abstract: The invention relates to an improved method for producing foamed material, especially poly(meth)acrylimide foams, which are foamed from polymer plates produced according to the casting method. The two-step method consists of a pre-heating step and at least one foaming step. The product obtained has a significantly smaller compressive strain, measured according to DIN 53425(ASMD 621), than prior art products.
Patent CA-2472042-C (CA)
Title: Pressing machine
Inventor: FUTAMURA SHOJI
IPC: B30B1/18
Filed: 2003-05-12
Granted: 2009-06-30
Abstract: A press forming machine having a slide plate which reciprocates by driving sources between a lower support stand and an upper support plate and has a forming space between the lower support stand and the slide plate. In the press forming machine, a reference plate for a displacement reference for the slide plate is supported on the lower support stand. The driving sources are engaged with the slide plate by the drive shafts of the driving sources to drive and press the slide plate. The drive shaft is provided with a through hole axially extending in a shaft center thereof, and displacement measuring devices each for each of the drive shafts measures the displacement of the slide plate portion corresponding to the through hole with respect to the reference plate, through the through hole. As a result, the displacements at the pressurized points on the slide plate can be measured.
Patent CA-2474165-C (CA)
Inventor: O'SULLIVAN ROBERT P
IPC: A45C11/26
Filed: 2004-07-14
Granted: 2009-02-24
Abstract: This invention relates to a novel design of ergonomic tool box. More particularly, this invention relates to a novel construction of ergonomic tool box which has upper and lower handles for ease of carrying, and an indented side which enables the ergonomic tool box to be carried closer to the vertical center of gravity of the carrier, thereby reducing strain on the carrier. An ergonomic tool box comprising: (a) an elongated hollow base with one of the sides of the base being indented inwardly towards the interior of the hollow base; (b) a handle disposed upwardly from the hollow base; and (c) at least one support for the handle extending upwardly between the base and the handle.
Patent CA-2479281-C (CA)
Inventor: MORISHITA YOSHIHIRO
IPC: C09J153/00
Filed: 2003-03-25
Granted: 2011-06-14
Abstract: La présente invention a trait à un copolymère acrylique à deux blocs de formule générale (I) utile dans la production d'adhésifs autocollants sensibles qui présentent une force de cohésion, un pouvoir adhésif et une aptitude à la fusion améliorés sans aucune diminution de résistance à la chaleur et aux intempéries, ainsi que des compositions adhésives autocollantes contenant ledit copolymère de formule (I): X . Y (I), dans laquelle X est un bloc polymère composé d'unités de méthacrylate d'alkyle dans lequel le groupe alkyle présente 1 à 4 atomes de carbone ou une structure cyclique ; Y est un bloc polymère composé d'unités d'acrylate d'alkyle dans lequel le groupe alkyle présente 5 à 20 atomes de carbone et/ou d'unités de méthacrylate d'alkyle dans lequel le groupe alkyle présente 5 à 20 atomes de carbone ; le poids moléculaire du degré moyen de polymérisation en poids de X est de 1000 à 8000 ; et le rapport pondéral X/Y est compris entre 1/99 et 10/90.
Patent CA-2480721-C (CA)
Title: Pressurised container for storing gaseous media under pressure
Inventor: JUNKER GERD
IPC: F17C1/00
Filed: 2003-04-09
Granted: 2008-06-17
Abstract: The invention relates to a pressurised container for storing gaseous media under pressure. Said container consists of a longitudinally welded pipe, which is sealed at both ends and comprises a filling and evacuation opening at least at one end. According to the invention, the longitudinally welded pipe (1, 2), produced according to the UOE process, has a diameter >= 508 mm and a minimum yield stress >= X 70. The open ends of said pipe are connected to and sealed by dome-shaped dish parts (4, 5). The pressurised container that is produced in this manner is designed for a minimum filling pressure of 200 bar at ambient temperature. One dish part (5) is provided with the filling and evacuation opening. The longitudinal weld seam (1, 2) and all other joint weld seams (3, 6, 7) of the pipe are configured with the highest possible fatigue limit with reference to high load amplitudes.
Patent CA-2485741-C (CA)
Inventor: SAMLER GARY R
IPC: B23K9/28
Filed: 2004-10-21
Granted: 2007-09-04
Abstract: A system and method for securing a welding electrode to a welding torch. The system comprises a collet body having a first portion that compresses an end of a collet against a welding electrode as the collet is urged against the first portion. The collet body also comprises an inner cylindrical portion that receives the compressed end of the collet and prevents the collet from expanding, thereby maintaining the collet compressed against the welding electrode. The method comprises urging the collet against the first portion of the collet body to compress the end portion of the collet against the welding electrode. The method also comprises urging the collet further into the collet body to dispose the end portion of the collet into the inner cylindrical portion of the collet body to prevent the end portion of the collet from expanding.
Patent CA-2487471-C (CA)
Title: Control of leak zone under blade platform
Inventor: GIOT CHANTAL
IPC: F01D11/00
Filed: 2003-05-28
Granted: 2011-07-12
Abstract: A system for controlling the leak zone under the platforms (34) of blades (33) belonging to the impeller (30) of a turbomachine is disclosed, using liners (10) having edges (13, 14, 15, 18) which are flared radially inwards. Said liners are disposed in the inter-blade cavities (37) which are defined by the platforms, the radial walls upstream and downstream of the blades and the periphery of the disk (31) of the impeller. According to the invention, one of the flared edges, upstream or downstream, comprises an elastic zone (18) which rests against a surface (39) of the adjacent radial wall (35), which is inclined in relation to a radial plane, such that, under the action of centrifugal forces, the liner (10) moves axially towards the opposite radial wall (36) in order to improve the sealing in said zone. Moreover, when the impeller stops, the aforementioned elastic zone (18) moves radially inwards and the liner (10) pivots around an axis (44) at a distance from said elastic zone (18).
Patent CA-2489876-C (CA)
Inventor: STELL RICHARD C
IPC: F28F27/02
Filed: 2003-06-27
Granted: 2011-04-19
Abstract: A process to increase the non-volatile removal efficiency in a flash drum in the steam cracking system. The gas flow from the convection section is converted from mist flow to annular flow before entering the flash drum to increase the removal efficiency. The conversion of gas flow from mist flow to annular flow is accomplished by subjecting the gas flow first to at least one expander and then to bends of various degrees and force the flow to change directions at least once. The change of gas flow from mist to annular helps coalesce fine liquid droplets and thus being removed from the vapor phase.
Patent CA-2492287-C (CA)
Inventor: COELINGH BENNINK HERMAN JAN TIJMEN
IPC: A61K45/06
Filed: 2003-07-11
Granted: 2011-12-13
Abstract: The present invention relates to a method of treating or preventing estrogen-sensitive tumours in a mammal, said method comprising the administration of a therapeutically effective amount of an estrogenic component to said mammal, wherein the estrogenic component is selected from the group consisting of:  substances represented by the following formula (I) in which formula R1, R2, R3, R4, independently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method; and mixtures of one or more of the aforementioned substances and/or precursors. The estrogenic component according to the invention does not have undesirable proliferative effects on breast and/or endometrial tissue and displays sufficient estrogenicity to prevent that its administration will lead to hypoestrogenism and/or climacteric complaints. Other aspects of the invention relate to pharmaceutical compositions, drug delivery systems and kits comprising the aforementioned estrogenic component in combination with an estrogen suppressant.
Patent CA-2495459-C (CA)
Title: Therapie d'echange de plasma selectif
Inventor: ROZGA JACEK
IPC: A61M1/34
Filed: 2003-08-11
Granted: 2009-10-27
Abstract: La présente invention concerne une technique permettant de prélever sur un patient une fraction de plasma spécifique contenant des substances dont le poids moléculaire est compris dans une plage spécifique. Cette invention concerne aussi un appareil de purification de plasma avec lequel cette technique peut être mise en oeuvre.
Patent CA-2503591-C (CA)
Title: Multipurpose dispenser
Inventor: GONZALEZ DE ECHAVARRI VICTOR
IPC: B67D7/08
Filed: 2003-09-11
Granted: 2010-11-30
Abstract: It comprises two deposits (7) and (10) having different products and means for dispensing each of them simultaneously or alternatively. A control plate (21) controls two motors (14, 15). The motor (15) transmits its movement via gears (16 and 17) to a pusher element (18) which acts on a push-button (19) arranged at the exit to the valve of deposit (7), dispensing the contents of said deposit either in a dropwise manner to channels or pipes, or by spraying it outside through a window (27) created for this purpose in the dispenser cover (5), and the motor (14) drives a fan (13) that circulates air containing the product held in deposit (10) that is evaporated by a cord (11), said air exiting to the outside via gratings (24, 25 or 26) according to the rotation direction of the fan (13).
Patent CA-2506563-C (CA)
Inventor: KUPPUSWAMY NAGARAJAN
IPC: C07C229/28
Filed: 2002-11-20
Granted: 2011-10-18
Abstract: L'invention concerne un procédé amélioré de préparation d'acides amino-méthyl-cycloalcane-acétiques. Elle porte notamment sur un procédé amélioré de préparation de gabapentine (chimiquement connu sous le nom d'acide 1-aminométhyl-1-cyclohexaneacétique) qui est un agent très connu, utile pour le traitement de l'épilepsie et d'autres troubles cérébraux. Dans la série chimique d'acides 1-aminométhyl-cycloalcane-1-acétiques, le Gabapentine, qui est un acide 1-aminométhyl-cyclohexane-1-acétique a été mis au point sous forme de médicament possédant des propriétés anticonvulsives.