baber/WOPTO huggingface dataset:
Patent RU-2761826-C1 (RU)
Title: Composition for the prevention or treatment of cancer, including a vessel-destroying agent and a taxane compound
Inventor: KIM SOO JIN
IPC: A61K31/427
Filed: 2019-05-17
Granted: 2021-12-13
Abstract: FIELD: medicine.SUBSTANCE: group of inventions relates to the field of medicine, namely to the field of oncology, and is intended for the prevention and treatment of lung cancer. A combination of therapeutically effective amounts of (S)-N-(4-(3-(1H-1,2,4-triazole-1-yl)-4-(3,4,5-trimethoxybenzoyl) phenyl) thiazole-2-yl)-2-amino-3-methylbutanamide for the prevention or treatment of lung cancer is presented, represented by the following formula 2, or its pharmacologically acceptable salt and the therapeutically effective amount of docetaxel or its pharmacologically acceptable salt. A method for the treatment of lung cancer is also presented, including the introduction of the above combination and the use of a combination to obtain a drug for the treatment of lung cancer.EFFECT: presented group of inventions provides an effective method for the treatment of lung cancer.formula 29 cl, 6 dwg, 4 tbl, 3 ex
Patent RU-2745493-C1 (RU)
Title: Способ строительства скважин на терригенные девонские отложения Ромашкинского месторождения нефти
Inventor: Faskhutdinov Ruslan Rustiamovich
IPC: E21B43/10
Filed: 2020-10-29
Granted: 2021-03-25
Abstract: Изобретение относится к нефтяной промышленности и, в частности, к строительству нефтяных скважин в осложнённых условиях обваливания неустойчивых горных пород. Технический результат - сокращение времени нахождения кыновских аргиллитов в необсаженном состоянии до 48 часов за счёт проведения геофизических исследований в 2 этапа, исключение осложнения при строительстве девонских скважин за счет исключения работ по проработке ствола скважины перед спуском эксплуатационной колонны. По способу осуществляют строительство скважины на терригенные девонские отложения Ромашкинского месторождения нефти. Для этого осуществляют бурение скважины, геофизические исследования, спуск эксплуатационной колонны и ее цементирование. При этом бурение останавливают на отметке 10-50 метров выше кровли кыновского горизонта. Производят промывку скважины буровым раствором. Затем проводят первый этап геофизических исследований по пробуренному стволу скважины. Далее бурят скважину до проектного забоя, вскрывая продуктивные кыновский и пашийский горизонты. Затем проводят второй этап геофизических исследований только в продуктивной части пласта. После этого без предварительной проработки ствола скважины спускают эксплуатационную колонну с прорабатывающим башмаком и цементируют ее. После затвердевания цемента приступают к освоению скважины.
Patent RU-2750321-C1 (RU)
Inventor: DZHEMILEV USEIN MEMETOVICH
IPC: C07F7/08
Filed: 2020-11-02
Granted: 2021-06-25
Abstract: FIELD: organic chemistry. 
     SUBSTANCE: invention relates to the field of organic chemistry. Proposed are diphenylhexaoxasyladispiroalkanes of formula (1) and a method for their preparation by the reaction of 1,1'-peroxy-bis-(1-hydroperoxycycloalkanes) with bis(methoxymethyl)diphenylsilane in the presence of La(NO 3 ) 3 ⋅6Н 2 О catalyst at room temperature and atmospheric pressure for 4-6 hrs.  
     EFFECT: proposed diphenylhexaoxasyladispiroalkanes expand the range of hydroxylation, peroxidation and oxidation to obtain polymers, and the proposed method allows them to be obtained selectively with high yield.  
     
       
     
     2 cl, 1 tbl, 3 ex
Patent RU-2753422-C1 (RU)
Title: Leak control system of the equipment of the secondary circuit in the buildings of a light water power reactor
Inventor: Beloglazov Andrei Vitalevich
IPC: G21C17/00
Filed: 2021-01-14
Granted: 2021-08-16
Abstract: FIELD: water power. 
     SUBSTANCE: invention relates to a leak control system of the equipment of the secondary circuit in the buildings of a light water power reactor. The system is comprised of an air humidity measurement apparatus including air humidity sensors 3, a signal processing unit 4 wherein the outputs of the air humidity sensors 3 are connected with said unit by analogue communication lines 6, and an information apparatus 5, the input whereof is connected with the output of the signal processing unit 4 via a digital communication line 7. At least one air humidity sensor 3 is located in a controlled building 1 with the controlled equipment installed therein. The rest of the air humidity sensors 3 are located in at least one auxiliary building 2 communicating by the aerial environment with the controlled building 1. The signal processing unit 4 includes a signal summation module 9. 
     EFFECT: increase in the reliability of the equipment of the secondary circuit of the reactor unit due to the provided possibility of timely detection, localisation of leak, and determination of the flow rate of the leak. 
     1 cl, 1 dwg
Patent RU-2766845-C1 (RU)
Title: Method of determining state of objects during vibration diagnostics
Inventor: SOLOVEVA TAMARA IVANOVNA
IPC: G01M7/02
Filed: 2021-01-29
Granted: 2022-03-16
Abstract: FIELD: test. 
     SUBSTANCE: invention relates to test equipment, in particular to a method of determining the state of objects during tests of aerospace or other equipment for vibration strength, and can be used to determine damages of load-bearing structures. When implementing the method, the structure is subjected to vibration in a given frequency range; at that, the structure is initially stabilized by the effect of broadband random vibration of a low level. After that, sinusoidal vibration tests are carried out at a low loading level. Then, standard mechanical loads are performed and sinusoidal vibration tests are repeated at low load level. For each load level, responses of the investigated structure are obtained in a given frequency range, in the form of dependence of vibration accelerations on frequency. According to the results of comparison of values of these parameters at two low levels of vibration loading, the state of integrity of the structure is determined. 
     EFFECT: improvement of reliability and validity of vibration diagnostics. 
     1 cl, 2 dwg
Patent RU-2756920-C1 (RU)
Title: Gluten-free dry mixture using corn and amaranth flour and fruit and vegetable and berry powders and method for producing gluten-free cake
Inventor: URUBKOV SERGEJ ALEKSANDROVICH
IPC: A21D13/066
Filed: 2021-02-04
Granted: 2021-10-07
Abstract: FIELD: food industry.  
     SUBSTANCE: group of inventions relates to the food industry. The group of inventions includes a gluten-free dry mixture using corn and amaranth flour and fruit and vegetable and berry powders and a method for producing a gluten-free cake using a gluten-free mixture. The gluten-free mixture contains corn flour, amaranth flour, apple powder and a powder selected from a group containing pumpkin, beet, cranberry powders. The initial components are taken in a certain ratio. Gluten-free dry mix may additionally contain dried cranberries or dried blueberries. In the method for producing a gluten-free cake using a gluten-free mixture, 45-80 g of granulated white sugar and two chicken eggs are whipped for 2-3 minutes, then a portion of 100 g of the gluten-free mixture is added and whipped again for 3-5 minutes. Without stopping mixing, water or milk are gradually added in an amount of 10-70 ml and the process continues until the components are completely evenly distributed. The resulting dough is cast into an aluminum or silicone mold and baked for 10-15 minutes at a temperature of 170-180°C.  
     EFFECT: group of inventions makes it possible to improve the quality indicators and the nutritional value of the finished product.  
     3 cl, 5 tbl, 3 ex
Patent RU-2771205-C1 (RU)
Title: QUANTIFICATION OF THE hsa-miR-30c-5/VIM, hsa-miR-28-3p/VIM, hsa-miR-1-3p/ANXA2, hsa-miR-30c-5p/FBN1, hsa-miR-15b-5p/MYL6 tr.v.1, hsa-miR-15b-5p/MYL6 tr.v.2, hsa-miR-185-3p/FLNA, hsa-miR-1-3p/YWHAZ, hsa-miR-30c-5p/YWHAZ AND hsa-miR-654-3p/FGA RATIO IN THE PLACENTAL SITE OF WOMEN ON THE DAY OF DELIVERY AT A TERM OF MORE THAN 34 WEEKS OF GESTATION AS A METHOD FOR DIFFERENTIAL DIAGNOSIS OF FETAL GROWTH RESTRICTION SYNDROME, PREECLAMPSIA AND A SMALL FOR GESTATIONAL AGE FETUS SYNDROME
Inventor: Timofeeva Anzhelika Vladimirovna
IPC: G01N33/58
Filed: 2021-02-05
Granted: 2022-04-28
Abstract: FIELD: medicine.SUBSTANCE: invention relates to the field of biomedicine, in particular, to obstetrics and molecular biology, and is intended for differential diagnosis of fetal growth restriction syndrome (FGR), preeclampsia (PE), and a small for gestational age fetus syndrome. The hsa-miR-30c-5p/VIM, hsa-miR-28-3p/VIM, hsa-miR-1-3p/ANXA2, hsa-miR-30c-5p/FBN1, hsa-miR-15b-5p/MYL6 tr.v.1, hsa-miR-15b-5p/MYL6 tr.v.2, hsa-miR-185-3p/FLNA, hsa-miR-1-3p/YWHAZ, hsa-miR-30c-5p/YWHAZ and hsa-miR-654-3p/FGA ratio is quantified in the placental site of women on the day of delivery at a term of more than 34 weeks of gestation. Logarithms of the values of said ratios to base two are calculated. Based on the above calculation, FGR, PE and the small for gestational age fetus syndrome are differentiated.EFFECT: invention ensures verification of the diagnosis made on the basis of clinical and laboratory research methods on the day of delivery to select the optimal management tactics for the mother and the child for the purpose of preventing possible postpartum complications.1 cl, 1 dwg, 4 tbl, 1 ex
Patent RU-2758772-C1 (RU)
Inventor: Erzhenkov Maksim Vladislavovich
IPC: G01N17/02
Filed: 2021-03-29
Granted: 2021-11-01
Abstract: Изобретение относится к устройствам для исследования коррозионной стойкости конструкционных материалов высокотемпературных устройств, преимущественно реакторов для работы с расплавами галогенидов щелочных металлов, применяемых в пирохимической и пирометаллургической переработке отработавшего ядерного топлива. Установка для определения скорости коррозии материалов в расплавленных солях содержит опорную платформу, контейнеры под нагреваемые тигли с образцами исследуемого материала, отличающаяся тем, что содержит три не связанные друг с другом металлические трубы, каждая из которых с одного конца герметично соединяется со съемной теплоотражающей крышкой, а с другого – с контейнером под нагреваемые тигли, выполненным в форме стакана, на опорной платформе смонтированы резьбовые шпили, на которые вертикально в несколько ярусов навинчены поперечные диски из теплоотражающего материала с тремя отверстиями для прохождения через них металлических труб. Техническим результатом является возможность одновременно осуществлять независимые друг от друга эксперименты в инертной среде, включая качественный и количественный анализ всех летучих продуктов, образовавшихся в ходе эксперимента, с минимизацией тепловых потерь. 6 ил.
Patent RU-2763843-C1 (RU)
Inventor: PONOMARENKO GENNADIJ NIKOLAEVICH
IPC: A61B5/00
Filed: 2021-03-29
Granted: 2022-01-11
Abstract: Изобретение относится к медицинской технике и может быть использовано в эстетической медицине и при протезировании конечностей. Устройство содержит подвижно соединенные между собой две бранши, контактные элементы, узел создания усилия для раздвижения бранш относительно друг друга и узел измерения этого смещения. Бранши соединены между собой планкой с возможностью линейного возвратно-поступательного смещения. Узел измерения этого смещения закреплен на бранше и в него введен электронный индикатор перемещения. Узел создания усилия для раздвижения бранш закреплен на бранше и в него введена балка с тензодатчиком и электронный индикатор этого усилия. Усилие на балку передается от тяги. Контактные элементы выполнены съемными и имеют с одной стороны штыри для фиксации к браншам через выполненные в них отверстия, а с другой стороны - контактную площадку для клеевой фиксации к участку кожи или рубцу кожи. Техническим результатом изобретения является расширение функциональных возможностей за счет обеспечения определения упругости участков не только гладкой (не пораженной рубцами) кожи, но и рубцов кожи, причем на участках не только конструктивно определенной, но и произвольной длины, а также повышение точности измерения за счет увеличения надежности крепления контактных элементов устройства к поверхности кожи и рубца кожи. 4 ил.
Patent RU-2759219-C1 (RU)
Title: Synchronous machine
Inventor: Smirnov Aleksandr Iurevich
IPC: H02K19/00
Filed: 2021-04-09
Granted: 2021-11-11
Abstract: FIELD: electrical engineering.SUBSTANCE: invention relates to the field of electrical engineering and can be used in electromechanical converters of the synchronous type with permanent magnets on the rotor. The effect is achieved by creating a similar-pole inductor machine containing a ring-shaped stator magnetic circuit with coils, one side of which passes through the hole of the ring-shaped magnetic circuit, connected to an electrical circuit of a multiphase armature winding with the number of phasesmconnected to phase terminals, forming 2ppairs of poles of alternating polarity around the circumference of the magnetic circuit, a magnetizing circuit of a magnetic circuit and a rotor with permanent magnets, while the coils are connected in coil groups of2qadjacent coils, whereqis the number of coils per pole and phase, included in phases according to, assembled in a star with a derived zero point, to which the beginnings of the coil are connected groups, and the anodes of the diodes are connected to the phase terminals, one in each phase, the cathodes of which are closed to an additional zero point equipped with a clamp.EFFECT: simplifying the design of a synchronous machine and reducing the material consumption of the windings by eliminating a separate bias winding.1 cl, 4 dwg
Patent RU-2769089-C1 (RU)
Title: Single-mode optical fibre with ultra-low attenuation and large effective area
Inventor: LO Venyun
IPC: G02B6/02
Filed: 2019-12-13
Granted: 2022-03-28
Abstract: FIELD: optics. 
     SUBSTANCE: single-mode optical fibre with ultra-low attenuation and large effective area comprises core layer (1), first, second, third and fourth cladding layers (5). First layer (2) of the shell is fluorine-doped quartz; second, third and fourth layers (5) of the shell are quartz. Third layer (4) of the shell comprises at least one annular microporous layer, which contains a plurality of evenly distributed micropores (40), wherein the centres of the circle of micropores (40) in each annular microporous layer are concicular, and the circles are concentric with layer (1) of the core. Core layer (1) is quartz doped with alkali metal, containing inner core layer (10) and core transition layer (11). Single-mode optical fibre has ultra-low attenuation and a large effective area and can realize fibre-optic transmission over a large-mode field and reduce the nonlinear effect of high-throughput transmission. 
     EFFECT: providing ultra-low attenuation characteristics and a large effective area and realizing fibre-optic transmission over a large-mode field and reducing the nonlinear effect of high-throughput transmission. 
     13 cl, 2 dwg, 2 tbl
Patent RU-2766813-C1 (RU)
Title: Method for prediction of the clinical course of transient tachypnea of newborns in term infants
Inventor: Kovtun Olga Petrovna
IPC: A61B5/02
Filed: 2021-06-30
Granted: 2022-03-15
Abstract: FIELD: medicine. 
     SUBSTANCE: invention refers to medicine, namely to neonatology, and can be used to predict the clinical course of transient tachypnea of newborns (TTN) in term infants. To this end, at the stage of the delivery room with the development of early manifestations of respiratory failure, the severity of the distress syndrome is assessed according to the Downes scale in points, Apgar score is taken into account at 1 and 5 minutes in points. Discriminant function d is then calculated using the developed formula. If d<0, the prognosis is unfavorable, the probability of admission to the NICU is high; if d>0, the prognosis is favorable. 
     EFFECT: invention makes it possible to predict the course of TTN at the stage of the delivery room and to determine the department for hospitalization of the newborn, which provides the timely implementation of the necessary therapeutic measures, reducing the severity of the course of TTN and avoiding possible complications. 
     1 cl, 1 dwg, 6 tbl, 3 ex
Patent RU-2765912-C1 (RU)
Title: Method for isolating stellate cells of the liver
Inventor: Maklakova Irina Yurevna
IPC: C12N5/071
Filed: 2021-07-29
Granted: 2022-02-04
Abstract: FIELD: medicine.SUBSTANCE: present invention relates to the field of cellular biology and medicine, in particular, to a method for obtaining stellate cells of the liver. To implement the method, mononuclear cells are first obtained in a solution of collagenase and pronase E enzymes. For this purpose, cells are isolated from the lateral lobe of the liver, it is thoroughly crushed and placed in the enzyme solution containing 3 mg of collagenase and 3 mg of pronase E. The cells are then resuspended in a histodensis solution, followed by centrifugation to produce a suspension. Gey's solution is then added to the suspension and re-centrifuged to wash off the histodensis. The supernatant is then removed and the cells are resuspended in a nutrient medium.EFFECT: present invention provides a possibility of obtaining stellate cells of the liver with a higher level of viability and with a large amount of obtained cells per unit mass of the liver and with a lower consumption of the amount of enzymes.1 cl, 2 tbl, 1 ex
Patent RU-2767818-C1 (RU)
Inventor: Ponomarev Sergei Nikolaevich
IPC: B67B3/20
Filed: 2021-08-03
Granted: 2022-03-22
Abstract: FIELD: cosmetic, pharmaceutical and chemical industries. 
     SUBSTANCE: present invention relates to a line for orientation and delivery (transportation) of such caps consistently and properly aligned and oriented for capping operations and can be used in the cosmetic, pharmaceutical and chemical industries. The line for supplying, orienting and capping caps with dispensers for bottles contains a hopper with a conveyor and agitator located in it, an inclined conveyor hopper located behind it, an inclined conveyor, a device for orienting caps with dispensers located behind it, made in the form of a shell with a bottom and a lid, while in the latter there is an inlet for lids with dispensers and an opening for unloading lids with dispensers from the orientation device, inside of which there are radially oriented cells for lids with dispensers; located behind the device for orienting covers with dispensers, made in the form of guides for the selection and rotation of covers with dispensers; guides horizontally located behind the lid selection and turning unit, an air duct with holes located above the horizontal guides, a capping unit. In the capping unit there are sensors for defects of caps with dispensers and a device for capturing caps with dispensers, made with the possibility of reciprocating movement to horizontally located guides, under which there is a device for fixing bottle containers and a device for orienting and guiding tubes of caps with dispensers into the neck of the container. The bottle tare rejection unit contains a bottle tare accumulator, bottle tare cutters, a bottle tare pusher and bottle tare detection sensors and a lid screwing unit with dispensers.  
     In the device for orienting lids with dispensers, there is a surface of rotation adjacent to the edges of the cells, the first and second partitions and two holes in the shell, while the first partition is located parallel to the vertical axis of the orientation device with an offset relative to it in the opposite direction from the inlet, and the second partition is located in the opening for unloading covers with dispensers perpendicular to the vertical axis of the drum. Each cell is formed by an inner wall formed by planes located at different angles of inclination to the vertical, side walls formed by the cell ribs, and an outer wall formed by the shell of the device for orienting caps with dispensers. 
     EFFECT: increasing the productivity of the process of feeding, orientation and capping of caps with a dispenser for bottles. 
     3 cl, 16 dwg
Patent RU-2765896-C1 (RU)
Title: Removable multi-turn fastening device for transporting large-capacity containers on universal flat wagons
Inventor: Shevtsov Andrej Mukhamedovich
IPC: B61D3/20
Filed: 2021-09-03
Granted: 2022-02-04
Abstract: FIELD: railway transport. 
     SUBSTANCE: invention relates to railway transport and is intended for transportation of large-capacity containers on universal platform wagons. A removable multi-turn fastening device for the transportation of large-capacity containers on flat wagons (RMTFD) consists of two end and two intermediate frames of a welded rectangular structure of longitudinal and transverse channels, fasteners connecting the frames to each other and fixing the structure by the clamps of the platform car. In each fastening body, a bolt stop is installed, having a plate-shaped platform at the end and equipped with a ball pin, and a washer with a fastener for fixing the frame after installation on the platform car. The frames are positioned so that the brackets of the platform car, for which they are fixed, are between the stops of each fastening at the same distance, and the stops are screwed in until they are fully connected to the side brackets of the platform car and are locked against unwinding with locknuts. For the possibility of supporting the frames during stacking, the platform on the frames is made in the form of a bent sheet that forms a supporting surface at the level of the surface of the folding fitting stop, a hole is made in the center of the sheet for linking the frames, the sheet is welded to the longitudinal channels of the frames. 
     EFFECT: increasing the reliability of fastening large-capacity containers on flat wagons by limiting movements in the longitudinal and transverse directions during transportation, as well as by eliminating the possibility of overturning containers in the transverse direction. 
     2 cl, 6 dwg
Patent RU-2771463-C1 (RU)
Inventor: Sidorov Aleksandr Stalevich
IPC: G21C9/016
Filed: 2021-10-26
Granted: 2022-05-04
Abstract: FIELD: mechanical engineering.SUBSTANCE: invention relates to the field of mechanical engineering, in particular to the support systems of the housing of the melt localization device. The support system includes a lower support, an upper support. The lower support consists of radial supports located in the lower part of the housing. The upper support contains lanyards, each of which contains an adjusting nut connecting the rods. At the ends of the rods, holes are made in the form of hyperbolic surfaces for connecting the housing with the embedded plates by means of fasteners. Said lanyards are installed tangentially to the body in pairs in such a way that the longitudinal axis of each radial support passes in the projection at an equidistant distance from the attachment points of the paired lanyards. In the eyes of the rods of each turnbuckle, flange stops are additionally installed, connected to each other by means of straight studs, fixed by means of fasteners, and installed parallel to each other with pretension.EFFECT: increased reliability of the melt localization device.1 cl, 6 dwg
Patent DE-3035824-C2 (DE)
IPC: D06M13/00
Filed: 1980-09-23
Granted: 1988-09-15
Abstract: Process for making fibrous material water repellent by treating it with an aqueous bath containing (A) an emulsified organo polysiloxane with at least 2 hydroxyl groups optionally modified in a manner able to cross-link, (B) a non-ionic emulsion of poly silicic acid ester, (C) a reaction product which has been obtained by reaction of an organic compound containing at least one halohydrin and/or epoxy group with an organic compound containing hydrogen atoms bound to nitrogen, which in form of its salt is water-soluble or at least water-dispersible. The treated material is dried and optionally cured.