baber/WOPTO huggingface dataset:
Patent SI-1697421-T1 (SI)
Title: Bispecific antibodies
Inventor: KUFER PETER
IPC: C07K14/705
Filed: 2004-12-22
Abstract: The present invention discloses bispecific antibodies comprising two antibody variable domains on a single polypeptide chain, wherein a first portion of the bispecific antibody is capable of recruiting the activity of a human immune effector cell by specifically binding to an effector antigen on the human immune effector cell, the first portion consisting of one antibody variable domain, and a second portion of the bispecific antibody specifically binding to a target antigen other than the effector antigen, the target antigen on a target cell other than the human immune effector cell, the second portion comprising one antibody variable domain.
Patent SI-2012763-T1 (SI)
Title: Pharmaceutical combination comprising 3- (3-dimethylamin0-1-ethyl-2-methyl-pr0pyl) -phenol and an nsaid
Inventor: SCHIENE KLAUS
IPC: A61K31/137
Filed: 2007-04-25
Abstract: A combination comprising as components (a) the compound 3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol, and (b) one or more non-steroidal anti-inflammatory drugs (NSAIDs); a pharmaceutical salt comprising said components; a compound derived from said components; a pharmaceutical formulation and a dosage form comprising said combination, salt, or compound; as well as a method of treating pain, e.g. chronic or acute pain, in a mammal characterized in that components (a) and (b) are administered simultaneously or sequentially to a mammal, wherein component (a) may be administered before or after component (b) and wherein components (a) or (b) are administered to the mammal either via the same or a different pathway of administration.
Patent SI-2068907-T1 (SI)
Title: Glycerol linked pegylated sugars and glycopeptides
Inventor: DEFREES SHAWN
IPC: C07K16/00
Filed: 2007-10-04
Abstract: The present invention provides conjugates between peptides and PEG moieties through glycerol linkers.
Patent SI-2280721-T1 (SI)
Title: Indoleamine 2, 3-dioxygenase based immunotherapy
Inventor: ANDERSEN MADS HALD
IPC: C12N9/00
Filed: 2009-04-17
Abstract: The present invention relates to the field of prophylaxis and therapy of cancer. In particular there is provided a protein lndoleamine 2,3-dioxygenase (IDO) or peptide fragments here of that are capable of eliciting anti-cancer immune responses. Specifically, the invention relates to the use of IDO or peptides derived here from or IDO specific T-cells for treatment of cancer. The invention thus relates to an anti-cancer vaccine which optionally may be used in combination with other immunotherapies and to IDO specific T-cells adoptively transferred or induced in vivo by vaccination as a treatment of cancer. It is an aspect of the invention that the medicaments herein provided may be used in combination with cancer chemotherapy treatment. A further aspect relates to the prophylaxis and therapy of infections by the same means as described above. The use of IDO and immunogenic peptide fragments hereof in cancer and infection treatment, diagnosis and prognosis is also provided.
Patent TR-200900591-T1 (TR)
Title: Bir kompresör
Inventor: BAYRAKTAR FARUK
IPC: F04B39/00
Filed: 2007-08-13
Abstract: Bu buluş, soğutucu akışkandan kaynaklanan gürültünün azaltılması bir emme susturucu (2) ile sağlanan, emme susturucunun (2) içinde, titreşim sönümlemesi görevi gören sönümleme odaları (4), soğutucu akışkanın geçtiği akış boruları (7), soğutucu akışkanın akış borularından (7) sönümleme odalarına (4) yayılmasını sağlayarak basınç dalgalarını sönümleyen açıklıklar (8) ve açıklığın (8) üzerinde hareket ettirilerek açıklığın (8) açılıp kapanmasını  veya kısmen kapatılarak alanının değiştirilmesini sağlayan bir akustik ayarlayıcı (acoustic tuning means) (9) içeren bir kompresör (1) ile ilgilidir.
Patent TR-201505451-T1 (TR)
Title: İki̇nci̇l şekle sahi̇p, hi̇droli̇k preste bi̇çi̇mlendi̇ri̇lmi̇ş tahri̇k mi̇li̇ tüpü.
Inventor: RYAN W LASKEY
IPC: F16C3/02
Filed: 2013-11-08
Abstract: Bir hidrolik preste biçimlendirilme işlemi kullanılarak hidrolik preste biçimlendirilmiş tahrik mili tüpü (100, 200) temin edilmektedir. Hidrolik preste biçimlendirme yöntemi kullanılarak üretilen tahrik mili tüpü (100, 200) bir birinci uç bölümü (102, 202), bir ikinci uç bölümü (106, 214) ve bir orta bölüm (104, 208) ihtiva eder. Orta bölüm (104, 208) en azından kısmen, dönme yüzeyini şekillendiren daire şeklinde bir yay tarafından tanımlanır. Orta bölümün (104, 208) en azından bir kısmı, birinci uç bölümünün (102, 202) ve ikinci uç bölümünün (106, 214) bir çapından daha büyük olan bir çapa sahiptir. Orta bölüm (104, 208), birinci uç bölümü (102, 202) ile ikinci uç bölümü (106, 214) arasında teşkil edilir. Orta bölüm (104, 208), hidrolik preste biçimlendirme yöntemi kullanılarak üretilen tahrik mili tüpünün (100, 200) bir kritik hızına ve bir soluklanma modu frekansına etki eder. Hidrolik preste biçimlendirilmiş tahrik mili tüpü (100, 200) bir tahrik mili düzeneğinin bir maliyetini düşürür.
Patent DE-3587258-T2 (DE)
Inventor: VALCAVI UMBERTO
IPC: C07D501/06
Filed: 1985-05-22
Granted: 1993-08-12
Abstract: A high yield process for preparing beta-lactam antibiotics having a high purity degree, in particular derivatives of the cephalosporanic and penicillanic acids, of the formula:by condensation of the compounds where X = H -OCH<sub>3</sub>, (suitably blocked), with a chloride of the formulawherein R = H, OH in which said condensation is carried out in the presence of a nicotinic or isonicotinic base.
Patent DE-3650384-T2 (DE)
Inventor: HARNDEN MICHAEL RAYMOND BEECHA
IPC: C07D239/50
Filed: 1986-12-11
Granted: 1996-06-13
Abstract: Compounds of formula (I), and a pharmaceutically acceptable salts thereof: <CHEM>  wherein:  R1 is hydrogen or CH2OH;  R2 is hydrogen or, (when R1 is hydrogen), hydroxy or CH2OH;  R3 is CH2OH or, (when R1 and R2 are both hydrogen), CH(OH)CH2OH;  R4 is hydrogen, hydroxy, amino or OR5 wherein R5 is C1-6 alkyl, phenyl or phenyl C1-2 alkyl either of which phenyl moieties may be substituted by one or two halo, C1-4 alkyl or C1-4 alkoxy groups; and in which any OH groups in R1, R2 and/or R3 may be in the form of O-acyl, phosphate, cyclic acetal or cyclic carbonate derivatives thereof; having antiviral activity, processes and intermediates for their preparation and their use as pharmaceuticals.
Patent DE-3650572-T2 (DE)
Inventor: LAUFFER RANDALL
IPC: A61B10/00
Filed: 1986-05-08
Granted: 1997-04-17
Abstract: A method of decreasing the NMR relaxation times (T1 or T2) of water protons in contact with a biological tissue, the method involving administering to a human patient an NMR contrast agent comprising a paramagnetic ion complexed with a chelating substance, the contrast agent being characterized in that it is capable of binding non-covalently and non-immunologically to a component of the tissue, and as a result of such binding is capable of enhancing relaxivity of the water protons by a factor of at least 2, compared to the relaxivity induced by the paramagnetic substance alone free in solution, and subjecting the patient to NMR imaging.
Patent DE-3782282-T2 (DE)
Inventor: ANDERSON RICHARD R
IPC: C12Q1/68
Filed: 1987-07-09
Granted: 1993-03-18
Abstract: A solid phase system incorporating a tetrazolium salt for use in a ligand receptor assay for the detection of a selection analyte in fluid sample is disclosed, wherein the tetrazolium salt functions to augment the color development of the indigogenic enzyme substrates used in such assays. The solid phase system comprises a solid support on which is localized in the same area a receptor and a tetrazolium salt. Methods for localizing the receptor on the solid support include chemical coupling and entrapment of receptor coated microspheres. The tetrazolium salt may be localized on the solid support by adsorption by hydrophobic interaction with the solid support or by entrapment of tetrazolium salt coated microspheres. The solid phase system is useful when incorporated in an apparatus for conducting ligand receptor assay processes. The use of the solid phase system in immunoassays and nucleic acid assays are described.
Patent DE-3786098-T2 (DE)
Inventor: HOTCHKISS ADAIR JOHN
IPC: C12Q1/56
Filed: 1987-03-11
Granted: 1993-12-16
Abstract: The in vivo thrombolytic status of human tissue-type plasminogen activator (t-PA), and/or at least one other coagulation/ fibrinolytic component in plasma, is determined by in vitro treatment of a plasma sample with an inhibitory amt. of D-Phe-Pro-Arg-chloromethyl ketone (I), then assaying for t-PA and/or the other components.
Patent DE-3788145-T2 (DE)
Inventor: OINUMA HITOSHI
IPC: C07D207/09
Filed: 1987-02-26
Granted: 1994-04-28
Abstract: A new piperidine compound is pharmacologically effective for treatment of the arrythmia and is defined by the formula:in which R<sup>1</sup> is a lower alkyl or a tolyl, R<sup>2</sup> is hydrogen, hydroxyl, a lower alkoxy or a lower alkyl, R<sup>3</sup> is hydrogen, a lower alkyl, a lower alkenyl, a cycloalkyl or a cycloalkylalkyl, X is -CO-, -CH<sub>2</sub>- or -CHOH-, g is an integer of 1 to 3, h is an integer of 1 to 3, Y is hydrogen, a lower alkyl, a lower alkenyl, cyano, -CH<sub>2</sub>COOR, R being hydrogen or a lower alkyl, a cycloalkyl, a cycloalkylalkyl,1 being 1 or 2, -A-B, A being -(CH<sub>2</sub>)n-, n being an integer of 1 to 5,a straight-chain alkylene group having 1 to 5 carbon atoms which is a divalent group derived from a straight-chain alkane having lower alkyl, phenyl or hydroxyl. group(s) bonded directly to one or more carbon atoms constituting said alkane by removing a hydrogen atom bonded to each of the carbon atoms placed at both ends thereof,a straight-chain alkylene group having 1 to 5 carbon atoms which is a divalent group derived from a straight-chain alkene having a double bond formed between carbon atoms adjacent to each other by removing a hydrogen atom bonded to each of the carbon atoms placed at both ends thereof,k being an integer of 2 to 5, - (CH<sub>2</sub>)p-CO-, p being an integer of 1 to 4, B being cyano, - NR<sup>4</sup>R<sup>5</sup>, a heterocyclic ring or a condensed aromatic ring. A pharmaceutical composition containing said compounds as active ingredient, and the use of said compound in the preparation of a medicament for the treatment of arrhythmia are also disclosed.
Patent DE-3851702-T2 (DE)
Inventor: EVERETT MARK A
IPC: B23K26/00
Filed: 1988-07-05
Granted: 1995-03-02
Abstract: A process for preventing crack formation in nickel alloy substrates having a gamma-prime phase includes providing a substrate comprised of a nickel alloy having a gamma-prime phase. A portion of the substrate is irradiated with a laser beam and thereby forms a molten pool of the alloy. A supply of coating particles are dispersed within the pool, the particles are comprised of a nickel alloy having gamma-prime forming constituents. Rapid relative motion between the beam and the pool is effected so that the pool rapidly solidifies and thereby minimizes the formation of gamma-prime therein and adjacent thereto.
Patent DE-3871536-T2 (DE)
Inventor: CHAMPSEIX SERGE
IPC: F16K31/10
Filed: 1988-01-11
Granted: 1993-05-06
Abstract: The invention provides a fluid switching microelectrovalve in which the mobile member playing the role of closure member for one or other of the pipes (18,19) is a single membrane (23) with oriented deformation applied by a rocker (24) against one or other of the pipes to be closed, the rocker (24) being moved from one to the other of its two balance positions corresponding to the two closure positions of the membrane by a spool (3) sliding in the valve body (1) under the action of the core of an electromagnet.
Patent DE-3885484-T2 (DE)
Inventor: ROSELLE BRIAN JOSEPH
IPC: C11D3/40
Filed: 1988-03-01
Granted: 1994-05-19
Abstract: Detergent compositions suitable for use in automatic dishwashing machines are disclosed. The compositions contain detergency builder materials, a chlorine bleach component, an optional low-foaming, bleach-stable surfactant and a relatively water-soluble stilbene dye which is color-stable with respect to said chlorine bleach component and which does not stain dishes etc.
Patent TR-199800868-T2 (TR)
Inventor: TAYLOR JOHN ANTHONY
IPC: D06P3/66
Filed: 1996-10-30
Abstract: Bir taban katmaninin boyanmasina yönelik bir proses; sözkonusu proses, adi geçen taban katmanina, 7'den büyük bir pH degerinde, bir poliamine bagli en az üç kromofor (renk verici) grubundan olusan, suda çözünür tepkin bir boya uygulamaya dayanir.Diger yandan, proseste kullanilmaya uygun boyalar da bulus kapsamindadir.
Patent TR-199801370-T2 (TR)
Inventor: PATEL AMRIT M
IPC: A61K8/81
Filed: 1997-01-13
Abstract: The present invention provides an effective conditioning shampoo composition which is free of conditioning amounts of silicone conditioning agents. It comprises: A) about 5% to about 40% of a detersive surfactant mixture of an anionic detergent and an amphoteric surfactant, the weight ratio of the anionic detergent to the amphoteric surfactant being in the range of about 10:1 to 0.8:1; B) about 0.05% to about 6% of a conditioning agent selected from the group consisting of 0.05% to 5% of a complex of essentially equimolar amounts of a C8-C18(EtO)1-10 carboxylic acid, and a C8-C18 alkyl (EtO)0-10 dimethyl amine; 0.05% to 1.0% of a polyquaternary compound selected from the group consisting of a quaternized cellulosic polymer and a mixture of the quaternized cellulosic polymer with a non-cellulosic quaternary conditioning polymer; and mixtures of the foregoing; C) 0.1% to 1% of a static control mixture of a quaternary ammonium salt having the formula R9, R10, R11, R12N+X- wherein R9 is a Cl4-C18 alkyl, R10 and R11 are each a C1-C4 alkyl, R12 is C1-C4 alkyl or benzyl and X- is a salt forming cation selected from the group consisting of chloride, bromide, methosulfate and ethosulfate; and a di-quaternary ammonium salt having the formula (R13)2R14R15N+X- wherein R13 is a C14-C18 alkyl or alkylene group and R14 and R15 are each a C1-C4 alkyl group or a (CH2CH2O)nH group with at least one of R14 and R15 being a (CH2CH2O)nH group, n is an integer from 2 to 20 and X is a cation as set forth above, the weight ratio of the monoalkyl quaternary salt to dialkyl quaternary salt being from about 1:4 to 4:1; and D) an aqueous medium. These compositions exhibit enhanced antistatic properties as compared to the same compositions containing either the monoalkyl quaternary salt or the dialkyl quaternary salt as the sole antistatic ingredient.
Patent TR-199902546-T2 (TR)
Inventor: ALISI ALESSANDRA
IPC: A61P9/06
Filed: 1998-04-02
Abstract: R1, R2, R3, R'3, R4, R5 ve R6'nin açiklamada ifade edilen anlamlara sahip oldugu, genel formül(I)'i, farmasötik açidan kabul edilebilir organik ve inorganik asitler ile birlikte bunun asit katki tuzlarini ve bunun farmasötik açidan kabul edilebilir dörtlü tuzlarini ihtiva eden bir bilesiktir.
Patent DE-60006002-T2 (DE)
Inventor: GRUSON BERTRAND
IPC: B67C3/26
Filed: 2000-11-20
Granted: 2004-08-05
Abstract: A filling spout having an adjustable flow rate and comprising a valve body receiving a valve member extending facing a valve seat, and a flow-rate adjustment member disposed upstream from the valve member and extending in register with a constriction in the valve body, the valve member and the flow-rate adjustment member being connected to a single actuator device via means allowing limited axial movement by enabling the adjustment member and the valve member to move axially relative to each other to a limited extent.
Patent DE-60012529-T2 (DE)
Inventor: SPERISEN THIERRY
IPC: C21D9/00
Filed: 2000-09-27
Granted: 2005-08-04
Abstract: An installation for the heat treatment of metal components comprises a transfer tunnel (6) with an airtight envelope (7) and a mobile chariot (8), an assembly of treatment elements (1, 2), at least one inlet and/or outlet lock (3) and a closing mechanism (24, 38, 41) for selectively sealing the passages formed by the treatment elements. The transfer tunnel extends over the treatment elements and the lock, so that their openings are above and the chariot is provided with a lifting mechanism capable of hooking to one of the charges (5) for suspended transporting and vertical displacement in order to introduce and extract it to and from the treatment elements.
Patent DE-60013467-T2 (DE)
Inventor: BYRNE PAUL
IPC: A63H18/16
Filed: 2000-03-06
Granted: 2006-01-12
Abstract: A racing car game which allows competitors to drive model racing cars on a flat track surface via control consoles. The ability to steer the racing cars on any part of the track as well as control speed and direction (forward/reverse) via steering wheel on console, with very short reaction time, gives the user a "Total racing car feel". The game is mains powered (no batteries needed) and therefore gives total unlimited playing time. The track is composed of sections allowing different geometric shapes to be designed.
Patent DE-60014859-T2 (DE)
Inventor: YEGOSHIN LEONID A
IPC: H04L45/24
Filed: 2000-01-12
Granted: 2005-03-03
Abstract: A communication system for an organization having multiple sites uses a dual-mode device capable of both cell phone communication and telephone communication on a local area network (LAN). IP LANS are established at organization sites such that a temporary IP address is assigned to a dual-mode device that logs onto an organization LAN, and the IP address is associated at a PSTN-connected server on the LAN with the cell phone number of the communication device. The IP server notifies a PSTN-connected routing server when a device logs on to a LAN, and also provides a destination number for the IP server. Cell calls directed to the device are then redirected to the IP server and directed to the device connected to the LAN.
Patent DE-60016660-T2 (DE)
Inventor: OOHASHI HIDEKAZU
IPC: B41N1/14
Filed: 2000-04-25
Granted: 2005-10-06
Abstract: A lithographic printing plate precursor is disclosed, comprising a support having thereon a photosensitive layer containing 6 wt% or more of an infrared absorbent which changes from hydrophilic to hydrophobic by heat, the support having a hydrophilic surface.
Patent DE-60033232-T2 (DE)
Inventor: SCHAER K
IPC: A61B17/00
Filed: 2000-05-11
Granted: 2007-11-15
Abstract: The present invention relates to a positioning system adapted to position and anchor one end of a medical device at a location where a pulmonary vein extends from an atrium, comprising: a transeptal sheath (50) adapted to be inserted through an atrial septum; an anchor device (10) having an elongate body with a proximal end portion and a distal end portion that is adapted to be positioned within the pulmonary vein, and also having an expandable member (14) along the distal end portion that is adjustable between a radially collapsed condition and a radially expanded condition that is adapted to engage the pulmonary vein after the distal end portion of the anchor device is advanced through the transeptal sheath and into the pulmonary vein; and a fixed corewire (18) within the elongate body, extending proximally from the distal end portion of the elongate body through at least a portion of the elongate body.an anchor device comprising an elongated tubular body having an expandable member disposed on its distal end portion.
Patent DE-60034668-T2 (DE)
Inventor: JACKWAY PAUL
IPC: G06T7/44
Filed: 2000-03-01
Granted: 2008-01-03
Abstract: A method and apparatus for image texture analysis in which the image is mapped into a first set of binary representation by a monotonically varying operator, such as a threshold operator. Each binary representation in the first set of binary representations is mapped to a further set of binary representations using a second monotonically varying operator, such as a spatial operator. The result of the two mappings is a matrix of binary image representations. Each binary image representation is allocated a scalar value to form an array of scalar values which may be analysed to identify defined texture characteristics.
Patent DE-60036292-T2 (DE)
Inventor: KADAMBI SHIRI
IPC: H04L12/54
Filed: 2000-08-18
Granted: 2008-05-29
Abstract: A network switch including at least one data port interface supporting a plurality of data ports, at least one stack link interface configured to transmit data between the network switch and other network switches, and a CPU interface configured to communicate with a CPU. A memory management unit in communication with the at least one data port interface and the at least one stack link interface is provided along with a memory interface in communication with the at least one data port interface and the at least one stack link interface, wherein the memory interface is configured to communicate with a memory. A communication channel is provided for communicating data and messaging information between the at least one data port interface, the at least one stack link interface, the memory interface, and the memory management unit, wherein the memory management unit is configured to route data received from each of the at least one data port interface and the at least one stack link interface to the memory interface.
Patent DE-60102453-T2 (DE)
Inventor: RILBE ULF
IPC: F16H1/32
Filed: 2001-01-24
Granted: 2005-03-03
Abstract: The invention relates to an eccentric gear for providing a speed difference between two machine elements (3, 4) which are rotatably journalled in relation to a reference member (2) and individually rotatable around a symmetry axis (C). The gear includes two pairs of co-operating gear rims (6, 7; 8, 9), one of which in each pair is eccentric in relation to the symmetry axis (C) and one of which is in the form of a male gear rim (6, 8) formed with out-turned teeth, and the other one (7, 9) is in the form of a female gear rim formed with in-turned teeth, which has a larger diameter than the appurtenant male gear rim (6, 7) in order to enable engagement of only a few of the teeth of the male gear rim in the female gear rim, one of the gear rims being arranged to roll off against the other one. According to the invention, one of the gear rims, e.g. the male gear rim, in each pair of co-operating gear rims is rigidly connected to a homologous gear rim in the other pair of gear rims and situated along a geometric axis (X) common for these two gear rims, which axis is eccentric and preferably oblique in relation to the symmetry axis (C) while the other gear rims are rotatable in relation to each other.
Patent DE-60102618-T2 (DE)
Inventor: MURATA AKIHISA
IPC: C09J7/38
Filed: 2001-05-14
Granted: 2004-08-19
Abstract: A heat-peelable pressure-sensitive adhesive sheet which, even when used for temporarily fixing electronic parts having poor resistance to static electricity, such as magnetic heads, is effective in preventing the yield of such electronic parts from being reduced by electrostatic breakage, while ensuring its functions of adhesiveness before heating and peelability after heating. The heat-peelable pressure-sensitive adhesive sheet comprises a substrate and formed on at least one side thereof a heat-expandable pressure-sensitive adhesive layer containing heat-expandable microspheres, wherein the heat-expandable pressure-sensitive adhesive layer has a surface resistivity of 10<12>  OMEGA / &squ&  or lower. In this heat-peelable pressure-sensitive adhesive sheet, the heat-expandable pressure-sensitive adhesive layer before heating may have a center line average surface roughness of 2  mu m or less and a maximum surface roughness of 5  mu m or less. The adhesive sheet may have a rubber-like organic elastic layer interposed between the substrate and the heat-expandable pressure-sensitive adhesive layer. <IMAGE>