baber/WOPTO huggingface dataset:
Patent WO-2021076565-A1 (WO)
Inventor: GREENSTEIN ANDREW
IPC: A61P35/00
Filed: 2020-10-14
Abstract: Methods for treating a cancer patient with a neutrophil-to-lymphocyte ratio (NLR) greater than 3 are disclosed, comprising administering a nonsteroidal glucocorticoid receptor antagonist (GRA) to such a cancer patient, effective to reduce the patient's NLR. The methods include administering a nonsteroidal GRA and a cancer treatment to such a cancer patient, effective to reduce the patient's NLR and enhance the treatment of the cancer patient. The GRA may be orally administered. The nonsteroidal GRA may be a nonsteroidal compound comprising a heteroaryl ketone fused azadecalin structure (e.g., relacorilant) or an octahydro fused azadecalin structure (e.g., exicorilant). The cancer treatment may include chemotherapy, immunotherapy, radiation therapy, administration of an anti-angiogenic agent, administration of a growth factor inhibitor, and surgery. The methods may enhance the cancer treatment, improve the prognosis of the cancer patient, improve the survival of the cancer patient, and provide beneficial clinical effects and advantages to the patient.
Patent WO-2021086974-A1 (WO)
Title: Wood polymer composites and additive systems therefor
Inventor: CHUN IKSOO
IPC: C08L23/00
Filed: 2020-10-28
Abstract: A wood polymer composite additive includes at least one maleic anhydride grafted polymer coupling agent, a second coupling agent that is at least one of a silane and siloxane, at least one peroxide crosslinking agent; and an amine compound. A wood polymer composite includes the additive, a thermoplastic polymer and cellulosic material. A wood polymer composite article is formed by extruding the composite material.
Patent WO-2021096773-A1 (WO)
Title: A precision medicine method for immunotherapy
Inventor: FURMAN DAVID
IPC: A61K38/19
Filed: 2020-11-06
Abstract: Cancer immunotherapy has achieved immense clinical success with long survival even in the most difficult to treat cancer. Yet this effect is only observed in a minority and there are no biomarkers of this response. The methods described herein reduce immunosenescence, improve cancer immunotherapy outcomes, vaccination outcomes, and/or treatment of infectious diseases using two independent measures of systemic chronic inflammation (the inflammatory age -iAge- and cytokine response score - CRS) to stratify patients into responders versus non-responders to cancer immunotherapy, vaccination, and/or anti-pathogen therapies. The iAge personalized immune proteome signature creates an individualized initial therapy to reduce iAge and to convert nonresponders patients into responders prior to treatment. Nonresponders can be converted to responders by treating the patients to reduce their iAge and improve their CRS.
Patent WO-2021102023-A1 (WO)
Inventor: QIU XIN
IPC: H04L29/06
Filed: 2020-11-18
Abstract: Devices, systems, and methods for securely transmitting information in a content distribution network, and in particular to a system and method for transmitting keys and other sensitive information within that network.
Patent WO-2021102124-A1 (WO)
Inventor: CHENG YUNGCHI
IPC: A61K31/38
Filed: 2020-11-19
Abstract: The disclosure provides a method of treating disease or disorder in a subject in need thereof by administering a therapeutically effective amount of an extract comprising at least one selective Farnesoid X receptor (FXR) agonist obtained from  Antrodia cinnamomea (Antrodia camphorate)  to the subject. The disease or the disorder includes liver disease, obesity, diabetes, diarrhea, abdominal pain, hypertension, itchy skin, liver cancer, hepatitis, biliary cholangitis, nonalcoholic steatohepatitis, primary sclerosing cholangitis, inflammation, and fibrosis.
Patent WO-2021126476-A1 (WO)
Title: Engine valve with raised ring or dimple
Inventor: KRIEGER JEFFREY CLARK
IPC: F01L3/20
Filed: 2020-11-23
Abstract: An engine valve (100, 200, 300) includes a stem (102), a head (104) comprising an outer lip surface (106), a seating surface (108) extending from the outer lip surface (106) toward the stem (102), and a combustion surface (110) extending from the outer lip surface (106) on the opposite side of the head (104) as compared to the seating surface (108). The combustion surface (110) includes a first convex arcuate surface (112) spaced away from the outer lip surface (106), at least partially forming a raised ring (114), and a first concave arcuate surface (116) spaced away from the outer lip surface (106), at least partially forming a dimple (118).
Patent WO-2021118919-A1 (WO)
Inventor: ABE MASATOSHI
IPC: C09D127/12
Filed: 2020-12-07
Abstract: A fluorinated composition includes a first fluorine-containing material having a melting point of at least 260°C and a reactive functional group content from 10 to 200 reactive functional groups for every 1,000,000 main chain carbon atoms. The fluorinated composition further includes a second fluorine-containing material having a melting point of at least 260°C and a reactive functional group content greater than at least 700 reactive functional groups for every 1,000,000 main chain carbon atoms. The reactive functional groups of the first and the second fluorine-containing materials are each independently selected from a group consisting of an anhydride group, a carbonyl group, a hydroxy group, an epoxy group, an isocyanate group, and combinations thereof. A ratio of the first fluorine-containing material to the second fluorine- containing material is from about 99/1 to about 20/80. The fluorinated composition has a yellow index (YI) of less than 60 as measured in accordance with ASTM-E513-96.
Patent WO-2021119220-A1 (WO)
Inventor: SAGAR RAJAT
IPC: H04L12/46
Filed: 2020-12-10
Abstract: A hub (702) that receives sensor data streams and then distributes the data streams to the various systems that use the sensor data. A demultiplexer (demux) (804) receives the streams, filters out undesired streams and provides desired streams to the proper multiplexer (mux) or muxes of a series of muxes (808A-808D). Each mux (808A-808D) combines received streams and provides an output stream to a respective formatter or output block (816A-816D). The formatter or output block (816A-816D) is configured based on the destination of the mux output stream, such as an image signal processor (614), a processor (616), memory (704) or external transmission (706). The output block (816A-816D) reformats the received stream to a format appropriate for the recipient and then provides the reformatted stream to that recipient.
Patent WO-2021011958-A1 (WO)
Inventor: NWACHUKWU CHISOMAGA
IPC: A61L9/01
Filed: 2020-07-15
Abstract: A freshening composition and method of jetting a freshening composition from a microfluidic device are provided. The composition includes greater than 5 wt. % of solubilizing materials that are liquid at 20°C. Each of the solubilizing materials have a Hansen polarity parameter (δp) of greater than 5 MPa0.5; a Hansen hydrogen-bonding parameter (δh) of greater than 9 MPa0.5; and a vapor pressure of less than 267 Pa. The method includes heating the freshening composition with a thermal actuator and atomizing the heated composition from a nozzle in a direction that is from 0 degrees to 90 degrees from the direction of gravitational force.
Patent WO-2021138655-A1 (WO)
Title: Wireless audio transmitter and receiver bone device using bone conduction
Inventor: SMOLARZ JOSEPH RYAN
IPC: A61C7/08
Filed: 2021-01-04
Abstract: The disclosure is directed to methods for transmitting vibrations via an electronic and/or transducer assembly through a user or wearer's tooth, teeth, jaw, and/or other bones. The disclosure is further directed to a system for transmitting vibrations via an electronic and/or transducer assembly through a user or wearer's tooth, teeth, jaw and/or other bones. The disclosure is further directed to an oral apparatus for implementation of methods and systems described herein.
Patent WO-2021146430-A1 (WO)
Title: Herbicide compositions with auxin herbicide monoethanolamine salts with improved properties
Inventor: JIMOH GANIYU
IPC: A01N39/04
Filed: 2021-01-14
Abstract: The present invention relates to the technical field of crop protection. The present invention primarily relates to herbicide compositions comprising as compound (A) ethyl [3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy]acetate and as compound (B) one or more monoethanolamine salts of auxin herbicides, in particular to formulations of a certain type and preferably containing further constituents, said compositions and formulations having improved properties. The invention also relates to methods of manufacturing such compositions and formulations and the use of such compositions and formulations.
Patent WO-2021158446-A1 (WO)
Title: System and methods for tracking, locating, and sharing plastic pallets
Inventor: CUNNINGHAM VINCENT
IPC: G06Q10/08
Filed: 2021-01-29
Abstract: A pallet tracking system for tracking a plurality of uniquely identified pallets is provided. The system includes a non-transitory storage device and a tracking circuit. The storage device maintains a pallet database of data concerning the pallets. The data concerning each pallet is accessible by the unique identifier of the pallet and includes a material composition of the pallet. The material composition is a portion of the data concerning the pallet and corresponding to a structural material from which the pallet itself is made. The tracking circuit receives the unique identifier of one such pallet from the pallet using a scanning device, retrieves the material composition of the pallet from the pallet database using the received unique identifier, and returns the retrieved material composition in response to a request. A pallet sharing system for sharing the pallets with a plurality of custodians using this pallet tracking system is also provided.
Patent WO-2021155315-A1 (WO)
Title: Wastewater treatment method
Inventor: BOCHER BENJAMIN
IPC: C02F1/28
Filed: 2021-01-29
Abstract: The present disclosure relates generally to processes and apparatuses for treating wastewater. Accordingly, one aspect of the disclosure provides a method for treating an effluent from a process for manufacturing an aromatic carboxylic acid, the effluent comprising organic matter and at least one sulfide-forming metal. The method includes contacting the manufacturing process effluent with a sulfide source in a precipitation zone to form a precipitated fraction comprising at least one metal sulfide, and a precipitation zone supernatant comprising a reduced amount of one or more sulfide-forming metals relative to the manufacturing process effluent. The method includes transferring at least a portion of the precipitation zone supernatant to an anaerobic zone comprising biomass; in the anaerobic zone, digesting at least a portion of the organic matter of the precipitation zone supernatant and forming a biogas stream comprising methane and hydrogen sulfide; transferring at least a portion of the biogas stream to the precipitation zone; wherein the sulfide source of the precipitation zone comprises hydrogen sulfide from the biogas stream.
Patent WO-2021178117-A1 (WO)
Inventor: TAHERZADEH BOROUJENI MAHMOUD
IPC: H04W74/08
Filed: 2021-02-10
Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) may transmit, to a base station, a first message of a two-step random access procedure. An attribute or content of the first message may indicate a request for a second type of control signaling that including fewer bits than a first type of control signaling. The UE may receive a second message of the two-step random access procedure including the second type of control signaling based on the first message. The UE may communicate with the base station on resources scheduled by the second message on a downlink shared channel.
Patent WO-2022025988-A1 (WO)
Inventor: SAPRA KAWAL
IPC: H04L29/08
Filed: 2021-02-26
Abstract: A method for providing network function (NF) discovery service enhancements includes receiving, by an NF repository function (NRF) from a consumer NF, a NF discovery request message that requests discovery of a network service hosted by producer NFs and includes at least one of a maximum payload size parameter and a profile count limit parameter and obtaining, by the NRF, NF profile objects corresponding to producer NFs that host the network service. The method further includes in response to determining that the consumer NF supports conditional limit features based on the at least one of the maximum payload size parameter and the profile count limit parameter, providing by the NRF to the consumer NF, a number of the NF profile objects that adheres to the at least one of the maximum payload size parameter and the profile count limit parameter indicated in the NF discovery request message.
Patent WO-2021183604-A1 (WO)
Inventor: LAU RONALD
IPC: B01F3/04
Filed: 2021-03-10
Abstract: L'invention concerne des procédés et un appareil qui permettent l'introduction efficace de gaz tels que l'air, l'oxygène et l'ozone dans des liquides aqueux. Les gaz sont introduits dans des liquides pour rendre ce gaz chimiquement ou biologiquement disponible pour une dépense d'énergie minimale. Des jets de liquide incidents sont dirigés dans un récipient de saturation sous pression ayant un espace libre rempli de gaz et une zone de saturation au-dessous de la surface du liquide à une vitesse suffisante pour créer une zone d'impact turbulent et de plongée. La turbulence résultante et le mélange de gaz et de liquide dans cette zone sous pression amène le gaz à être entraîné vers le liquide dans le récipient et décompose le gaz et le liquide en un écoulement de brassage et crée un grand nombre de bulles. Le liquide enrichi en gaz résultant est évacué du récipient au niveau d'une sortie pour assurer un minimum de bulles dans le liquide enrichi en gaz.
Patent WO-2021188877-A1 (WO)
Title: Point-of-care digital microfluidics for sepsis diagnosis
Inventor: LIU YUGUANG
IPC: A61M1/36
Filed: 2021-03-19
Abstract: This document provides digital microfluidics devices. For example, point-of-care digital microfluidics devices for removing white blood cells from a blood sample and preparing bacterial DNA in the sample for detection and/or identification are provided.
Patent WO-2021188982-A1 (WO)
Title: Electronic devices with standing mechanisms for improved user experience
Inventor: CHOW KENDALL
IPC: G06F3/147
Filed: 2021-03-19
Abstract: Standing mechanisms including supports are described for providing a fixed or configurable lean or tilt to large form factor electronic devices. In one embodiment, a support for a large form factor electronic device comprises a base support to provide a fixed or configurable angle to provide a lean to the large form factor electronic device. An upper support supports a backside of a display panel of the large form factor electronic device.
Patent WO-2021225703-A1 (WO)
Title: Efficient positioning enhancement for dynamic spectrum sharing
Inventor: GUMMADI BAPINEEDU
IPC: G01S1/04
Filed: 2021-03-22
Abstract: Techniques are provided for transmitting Positioning Reference Signals (PRSs) in cells supporting two different Radio Access Technologies (RATs), where the two RATs (e.g. 4G LTE and 5G NR) employ dynamic spectrum sharing. To avoid interference between the PRSs and between the two RATs, the PRSs may be time aligned to the same set of PRS positioning occasions, and may be assigned orthogonal characteristics such as different muting patterns, orthogonal code sequences, different frequency shifts or different frequency hopping. UEs supporting both RATs may be enabled to measure PRSs for both RATs. UEs supporting only one RAT (e.g. 4G LTE) may be enabled to measure PRSs for just this RAT. A location server such as an LMF, E-SMLC or SLP may provide assistance data to UEs, and request measurements from UEs, for PRSs in one or both RATs.
Patent WO-2021195531-A1 (WO)
Title: Réseau domestique utilisant de multiples protocoles de mise en réseau sans fil
Inventor: JUNTUNEN ROBERT D
IPC: H04L29/08
Filed: 2021-03-26
Abstract: Un dispositif capteur comprend un circuit de traitement configuré pour transmettre, dans une première bande passante, des premières données de bande passante à un dispositif concentrateur à l'aide d'une première connexion sans fil configurée pour un premier protocole sans fil. En réponse à la détermination du fait que le dispositif capteur comprend des secondes données de bande passante à transmettre au dispositif concentrateur dans une seconde bande passante, le circuit de traitement est configuré pour transmettre une seconde demande de connexion sans fil au dispositif concentrateur à l'aide de la première connexion sans fil. En réponse au fait que le dispositif concentrateur transmet des informations permettant d'établir une seconde connexion sans fil avec le dispositif capteur, le circuit de traitement est configuré pour établir la seconde connexion sans fil pour un second protocole sans fil différent du premier protocole sans fil. Le circuit de traitement est configuré pour transmettre, dans la seconde bande passante, les secondes données de bande passante au dispositif concentrateur à l'aide de la seconde connexion sans fil. La seconde bande passante est supérieure à la première bande passante.
Patent WO-2021203055-A1 (WO)
Inventor: FRUEH FELIX
IPC: A61K45/06
Filed: 2021-04-02
Abstract: La présente invention concerne des inhibiteurs d'entrée virale et des inhibiteurs de l'ARN polymérase, des compositions pharmaceutiques comprenant un ou plusieurs de ceux-ci, et des combinaisons de thérapies, ainsi que des méthodes de fabrication et d'utilisation de ce qui précède dans le traitement de certaines maladies.
Patent WO-2021211603-A1 (WO)
Title: Systems and methods for ai-assisted surgery
Inventor: Kumar Bipul
IPC: A61B5/00
Filed: 2021-04-13
Abstract: Various embodiments of the invention provide systems and methods to assist or guide an arthroscopic surgery or other surgical procedure e.g., surgery of the shoulder, knee or hip. The method comprises steps of receiving an image from an interventional imaging device, identifying a feature in the image using an image recognition algorithm, overlaying the features on a video feed on a display device and making recommendations or suggestions to an operator based on the identified feature in the image.
Patent WO-2021211942-A1 (WO)
Title: Precision delivery of multi-scale payloads to tissue-specific targets in plants
Inventor: MARELLI BENEDETTO
IPC: A61K33/42
Filed: 2021-04-16
Abstract: The invention provides a silk-based biomaterial designed to fabricate a microneedle-like device with controlled degradation rate in planta via tuning material composition and methods of manufacture thereof. The device enables precise access to xylem, phloem, and other plant tissues, thus being capable of serving as delivery tool to release cargo payloads and as sampling tool for analysis of plants fluid.
Patent WO-2021222786-A1 (WO)
Inventor: TIWARI DURGESH
IPC: G06T7/73
Filed: 2021-04-30
Abstract: One variation of a method for maintaining perpetual inventory within a store includes: accessing a radar scan of an inventory structure within a store; accessing an optical image of the inventory structure; identifying a product type associated with the slot in a region of the optical image; retrieving a volumetric definition of the product type; locating a slot volume defining the slot in the radar scan; extracting a volumetric representation of a set of product units intersecting the slot volume in the radar scan; segmenting the volumetric representation by the volumetric definition to calculate a quantity of the set of product units occupying the slot; and updating a stock record of the store to reflect the quantity of the set of product units occupying the slot.
Patent WO-2021247567-A1 (WO)
Inventor: CURIEL DAVID
IPC: A61K39/235
Filed: 2021-06-01
Abstract: Compositions and methods for treating a viral infection may comprise use of an adenoviral vector. An adenoviral vector of the present disclosure may comprise a non-human adenoviral genome with one or more gene locus functionally removed and a transgene. A method of treating a viral infection may comprise administering a composition comprising an adenoviral vector of the present disclosure, to a subject and reducing the infectivity or transmission of the virus. Intranasal administration provides enhance protection of the upper respiratory tract of a subject relative to intramuscular administration.
Patent WO-2021252396-A1 (WO)
Title: Constraints on number of subpicture in a video picture
Inventor: WANG YE-KUI
IPC: H04N13/00
Filed: 2021-06-07
Abstract: Several techniques for video encoding and video decoding are described. One example method includes performing a conversion between a video and a bitstream of the video according to a rule. The rule specifies that a subpicture sequence includes (1) all subpictures within the target CVSs that have a same subpicture index and belong to layers in the multi-subpicture layers, and (2) all subpictures in the target CVSs that have a subpicture index of 0 and belong to layers of the OLSs but not in the multi-subpicture layers.
Patent WO-2021252807-A1 (WO)
Title: Methods of use of allergen-specific t cells in allergy and asthma
Inventor: SEUMOIS GREGORY
IPC: A61P37/08
Filed: 2021-06-10
Abstract: Disclosed herein are methods of detecting an antigen-specific T cell (e.g., a HDM-reactive T cell) expressing IL-9 which contribute to a worsening of an allergy (e.g., a HDM-induced allergy) or detecting an antigen-specific T cell (e.g., a HDM-reactive T cell) associated with a positive prognosis. In some embodiments, also disclosed herein is a method of treating an allergy (e.g., a HDM-induced allergy) in a subject in need thereof based on the presence or absence of an antigen-specific T cell (e.g., a HDM-reactive T cell) that express IL-9.
Patent WO-2021257965-A1 (WO)
Inventor: CUEVA GABRIEL
IPC: H01L31/0328
Filed: 2021-06-18
Abstract: Structures for suppressing parasitic acoustic waves in semiconductor structures and integrated circuit devices are described. Such integrated circuit devices can, typically, produce undesirable acoustic wave resonances, and the acoustic waves can degrade the performance of the devices. In that context, some embodiments described herein relate to spoiling a conductive path that participates in the generation of acoustic waves. Some embodiments relate to spoiling acoustic characteristics of an acoustic resonant structure that may be present in the vicinity of the device. Combined embodiments that spoil the conductive path and acoustic characteristics are also possible.
Patent WO-2021262578-A1 (WO)
Inventor: PROVAZNIK RICHARD
IPC: E01F15/00
Filed: 2021-06-21
Abstract: A road barrier transfer machine includes an improved capstan control system that reduces unwanted migration of road barrier spans without requiring inaccurate visual observations and reliance on outdated scripts. The barrier transfer machine includes a moveable chassis, an entry snout, an exit snout, a conveyor system, a capstan system, and the capstan control system. The capstan control system automatically operates the capstan system or provides instructions to an operator of the machine to maintain the tension and compression of a road barrier span within desired ranges to reduce unwanted migration of the span.
Patent WO-2022010641-A1 (WO)
Title: Method for welding a titanium component with a titanium nitride coating
Inventor: ZHAO HAILIANG
IPC: B23K101/36
Filed: 2021-06-22
Abstract: A workpiece (32) of Ti or a Ti alloy includes a surface with a coating layer of titanium nitride. A region of the surface includes a connection zone (34)of a Ti-N solid solution alloy. A second Ti or Ti alloy workpiece (42) is contacted with the connection zone, and a weld joint (55) is formed across the connection zone with a resistance welding process. The weld joint (55) extends into the first Ti workpiece (32) and the second Ti workpiece (42).