Patent AU-2008229967-B2 (AU)
Title: Novel streptococcus antigens
Inventor: HAMEL JOSEE
IPC: A61K39/09
Filed: 2008-10-16
Granted: 2012-07-05
Abstract: Streptococcus proteins and polynucleotides encoding them are disclosed. Said proteins are antigenic and therefore useful vaccine components for the prophylaxis or therapy of streptococcus infection in animals. Also disclosed are recombinant methods of producing the protein antigens as well as diagnostic assays for detecting streptococcus bacterial infection. ATGAAATTTA GTAAAAAATA TATAGCAGCT GGATCAGCTG TTATCGTATC CTTGAGTCTA 60 TGTGCCTATG CACTAAACCA GCATCGTTCG CAGGAAAATA AGGACAATAA TCGTGTCTCT 120 TATGTGGATG GCAGCCAGTC AAGTCAGAAA AGTGAAAACT TGACACCAGA CCAGGTTAGC 180 CAGAAAGAAG GAATTCAGGC TGAGCAAATT GTAATCAAAA TTACAGATCA GGGCTATGTA 240 ACGTCACACG GTGACCACTA TCATTACTAT AATGGGAAAG TTCCTTATGA TGCCCTCTTT 300 AGTGAAGAAC TCTTGATGAA GGATCCAAAC TATCAACTTA AAGACGCTGA TATTGTCAAT 360 GAAGTCAAGG GTGGTTATAT CATCAAGGTC GATGGAAAAT ATTATGTCTA CCTGAAAGAT 420 GCAGCTCATG CTGATAATGT TCGAACTAAA GATGAAATCA ATCGTCAAAA ACAAGAACAT 480 GTCAAAGATA ATGAGAAGGT TAACTCTAAT GTTGCTGTAG CAAGGTCTCA GGGACGATAT 540 ACGACAAATG ATGGTTATGT CTTTAATCCA GCTGATATTA TCGAAGATAC GGGTAATGCT 600 TATATCGTTC CTCATGGAGG TCACTATCAC TACATTCCCA AAAGCGATTT ATCTGCTAGT 660 GAATTAGCAG CAGCTAAAGC ACATCTGGCT GGAAAAAATA TGCAACCGAG TCAGTTAAGC 720 TATTCTTCAA CAGCTAGTGA CAATAACACG CAATCTGTAG CAAAAGGATC AACTAGCAAG 780 CCAGCAAATA AATCTGAAAA TCTCCAGAGT CTTTTGAAGG AACTCTATGA TTCACCTAGC 840 GCCCAACGTT ACAGTGAATC AGATGGCCTG GTCTTTGACC CTGCTAAGAT TATCAGTCGT 900 ACACCAAATG GAGTTGCGAT TCCGCATGGC GACCATTACC ACTTTATTCC TTACAGCAAG 960 CTTTCTGCTT TAGAAGAAAA GATTGCCAGA ATGGTGCCTA TCAGTGGAAC TGGTTCTACA 1020 GTTTCTACAA ATGCAAAACC TAATGAAGTA GTGTCTAGTC TAGGCAGTCT TTCAAGCAAT 1080 CCTTCTTCTT TAACGACAAG TAAGGAGCTC TCTTCAGCAT CTGATGGTTA TATTTTTAAT 1140 CCAAAAGATA TCGTTGAAGA AACGGCTACA GCTTATATTG TAAGACATGG TGATCATTTC 1200 CATTACATTC CAAAATCAAA TCAAATTGGG CAACCGACTC TTCCAAACAA TAGTCTAGCA 1260 ACACCTTCTC CATCTCTTCC AATCAATCCA GGAACTTCAC ATGAGAAACA TGAAGAAGAT 1320 GGATACGGAT TTGATGCTAA TCGTATTATC GCTGAAGATG AATCAGGTTT TGTCATGAGT 1380 CACGGAGACC ACAATCATTA TTTCTTCAAG AAGGACTTGA CAGAAGAGCA AATTAAGGCT 1440 GCGCAAAAAC ATTTAGAGGA AGTTAAAACT AGTCATAATG GATTAGATTC TTTGTCATCT 1500 CATGAACAGG ATTATCCAGG TAATGCCAAA GAAATGAAAG ATTTAGATAA AAAAATCGAA 1560 GAAAAAATTG CTGGCATTAT GAAACAATAT GGTGTCAAAC GTGAAAGTAT TGTCGTGAAT 1620 AAAGAAAAAA ATGCGATTAT TTATCCGCAT GGAGATCACC ATCATGCAGA TCCGATTGAT 1680 GAACATAAAC CGGTTGGAAT TGGTCATTCT CACAGTAACT ATGAACTGTT TAAACCCGAA 1740 GAAGGAGTTG CTAAAAAAGA AGGGAATAAA GTTTATACTG GAGAAGAATT AACGAATGTT 1800 GTTAATTTGT TAAAAAATAG TACGTTTAAT AATCAAAACT TTACTCTAGC CAATGGTCAA 1860 AAACGCGTTT CTTTTAGTTT TCCGCCTGAA TTGGAGAAAA AATTAGGTAT CAATATGCTA 1920 GTAAAATTAA TAACACCAGA TGGAAAAGTA TTGGAGAAAG TATCTGGTAA AGTATTTGGA 1980 GAAGGAGTAG GGAATATTGC AAACTTTGAA TTAGATCAAC CTTATTTACC AGGACAAACA 2040 TTTAAGTATA CTATCGCTTC AAAAGATTAT CCAGAAGTAA GTTATGATGG TACATTTACA 2100 GTTCCAACCT CTTTAGCTTA CAAAATGGCC AGTCAAACGA TTTTCTATCC TTTCCATGCA 2160 GGGGATACTT ATTTAAGAGT GAACCCTCAA TTTGCAGTGC CTAAAGGAAC TGATGCTTTA 2220 GTCAGAGTGT TTGATGAATT TCATGGAAAT GCTTATTTAG AAAATAACTA TAAAGTTGGT 2280 GAAATCAAAT TACCGATTCC GAAATTAAAC CAAGGAACAA CCAGAACGGC CGGAAATAAA 2340 ATTCCTGTAA CCTTCATGGC AAATGCTTAT TTGGACAATC AATCGACTTA TATTGTGGAA 2400 GTACCTATCT TGGAAAAAGA AAATCAAACT GATAAACCAA GTATTCTACC ACAATTTAAA 2460 AGGAATAAAG CACAAGAAAA CTCAAAACTT GATGAAAAGG TAGAAGAACC AAAGACTAGT 2520 GAGAAGGTAG AAAAAGAAAA ACTTTCTGAA ACTGGGAATA GTACTAGTAA TTCAACGTTA 2580 GAAGAAGTTC CTACAGTGGA TCCTGTACAA GAAAAAGTAG CAAAATTTGC TGAAAGTTAT 2640 GGGATGAAGC TAGAAAATGT CTTGTTTAAT ATGGACGGAA CAATTGAATT ATATTTACCA 2700 TCAGGAGAAG TCATTAAAAA GAATATGGCA GATTTTACAG GAGAAGCACC TCAAGGAAAT 2760 GGTGAAAATA AACCATCTGA AAATGGAAAA GTATCTACTG GAACAGTTGA GAACCAACCA 2820 ACAGAAAATA AACCAGCAGA TTCTTTACCA GAGGCACCAA ACGAAAAACC TGTAAAACCA 2880 GAAAACTCAA CGGATAATGG AATGTTGAAT CCAGAAGGGA ATGTGGGGAG TGACCCTATG 2940 TTAGATCCA6 CATTAGAGGA AGCTCCAGCA GTAGATCCTG TACAAGAAAA ATTAGAAAAA 3000 TTTACAGCTA GTTACGGATT AGGCTTAGAT AGTGTTATAT TCAATATGGA TGGAACGATT 3060 GAATTAAGAT TGCCAAGTGG AGAAGTGATA AAAAAGAATT TATCTGATTT CATAGCGTAA 3120 (SEQ ID NO: 1) FIGURE 1