baber/WOPTO huggingface dataset:
Patent EP-4267757-A1 (EP)
Title: Methods and systems for analyzing methylated polynucleotides
Inventor: HITE DUSTIN HOWARD
IPC: C12Q1/6806
Filed: 2021-12-22
Abstract: In an aspect, a method for detecting the presence or absence of cancer, comprising: (a) obtaining the polynucleotide sample from the subject; (b) partitioning the polynucleotide sample based on methylation status into plurality of partitioned sets to generate partitioned polynucleotides; (c) fragmenting the partitioned polynucleotides from at least one of the plurality of partitioned sets to generate fragmented polynucleotides; (d) tagging the fragmented polynucleotides to generate tagged polynucleotides; (e) concatenating the tagged polynucleotides to generate concatenated polynucleotides; (f) processing the concatenated polynucleotides to generate processed polynucleotides, wherein the processing comprises amplification; (g) sequencing the processed polynucleotides to generate a set of sequencing reads; (h) analyzing the set of sequencing reads to detect a methylation status of a plurality of genomic regions; and (i) detecting the presence or absence of cancer from the methylation status of the plurality of genomic regions.
Patent EP-4191924-A1 (EP)
Title: Beam indication method and apparatus, terminal and network side device
Inventor: LI HUI
IPC: H04L5/00
Filed: 2021-07-21
Abstract: A beam indication method, a beam indication apparatus, a terminal and a network side device are provided. When the method is applied to a terminal side, the method includes: receiving by the terminal an indication message configured to indicate a first beam direction for transmitting a first object, where the first beam direction is the same as or different from a second beam direction used by the terminal for transmitting a second object, the first object and the second object are one of a channel and a reference signal, and the first beam direction is a direction indicated by a TCI state in a preconfigured TCI state set; and transmitting by the terminal the first object according to the first beam direction.
Patent EP-4201236-A1 (EP)
Inventor: SHI WEN
IPC: A24F40/40
Filed: 2021-08-20
Abstract: This application provides an e-cigarette, an e-cigarette atomizer, and an atomization assembly. The e-cigarette atomizer includes: a liquid storage cavity, configured to store a liquid substrate; a porous body, in fluid communication with the liquid storage cavity to absorb the liquid substrate; and a heating element, including a first electrode connection portion, a second electrode connection portion, and a resistance heating trajectory extending between the first electrode connection portion and the second electrode connection portion, where a curvature of any position on a part of the resistance heating trajectory close and connected to the first electrode connection portion and/or the second electrode connection portion is not zero. The heating element of the e-cigarette atomizer adopts the resistance heating trajectory to perform heating, and causes a part of the resistance heating trajectory that is close and connected to an electrode connection portion to be in a bending shape whose curvature is not zero. Therefore, internal tensile stress formed due to a deformation difference is eliminated, and the heating element is prevented from being deformed or broken under cold-hot cycling.
Patent EP-4064510-A1 (EP)
Inventor: LI LINFU
IPC: H01M10/44
Filed: 2021-08-25
Abstract: This application provides a battery charging control method and device. Voltages of N cells in an M<sup>th</sup> sampling period are obtained, and a voltage of the battery at each sampling moment among K sampling moments in said sampling period is calculated. Charging of the battery is stopped when the voltage of the battery increases monotonically in the M<sup>th</sup> sampling period and a trend of a fitting curve of the voltage of at least one cell among the N cells in said sampling period is not rising.
Patent EP-4213847-A1 (EP)
Inventor: POLISETTI DHARMA RAO
IPC: A61K31/4738
Filed: 2021-09-17
Abstract: The present invention provides an amorphous form of (S)-2-(3S,8S)-3-(4-(3,4-dichlorobenzyloxy)phenyl-7-((S)-1-phenylpropyl)-2,3,6,7,8,9-hexahydro-[1,4]-dioxino[2,3-g]isoquinolin-8-ylformylamino)-3-(4-(2,3-dimethylpyridin-4-yl)phenyl)propionic acid dihydrochloride salt, pharmaceutical compositions comprising the same, methods of preparation and use thereof in treating conditions, such as diabetes, where modulation of the human GLP-1 receptor is beneficial.
Patent EP-4225358-A1 (EP)
Inventor: GARON EDWARD B
IPC: A61K39/00
Filed: 2021-10-06
Abstract: L'identification d'un cancer sensible au blocage du point de contrôle immunitaire (ICB) comprend le séquençage d'acide nucléique contenu dans un échantillon biologique; et l'identification du cancer comme sensible à l'ICB lorsque le séquençage détecte un acide nucléique codant pour un néo-épitope qui est un nonamère comprenant une substitution radicalaire dans la seconde position. Ceci permet la sélection d'une stratégie de traitement qui améliore l'efficacité de l'ICB, sur la base du profil du patient. Le patient peut être traité avec un agent qui améliore la sensibilité à l'ICB, en modifiant le profil d'épitope à motif du sujet ou en administrant un agent sensibilisant. Le traitement peut être effectué avec des cellules présentatrices d'antigène (CPA) entraînées avec un néo-épitope associé au cancer du sujet. Pour des sujets exprimant le supertype B44 de HLA, la substitution radicalaire est constituée d'un acide aminé chargé négativement, tandis que pour des sujets exprimant le supertype B27 de HLA, la substitution radicalaire est constituée d'un acide aminé chargé positivement.
Patent EP-4230637-A1 (EP)
Title: Radioactive complexes of anti-her2 antibody, and radiopharmaceutical
Inventor: KAWATANI Minoru
IPC: C07K1/13
Filed: 2021-10-15
Abstract: The present invention provides a conjugate which has stability improved more than conventional conjugates without impairing the efficacy. The conjugate of the present invention is a conjugate of an anti-HER2 antibody site-specifically modified with a peptide and a chelating agent, wherein the chelating agent is chelated with a metal radionuclide, the peptide and the chelating agent are linked by a linker (L), and the linker (L) does not contain a thiourea bond.
Patent EP-4228597-A1 (EP)
Inventor: SUKURU KARUNAKAR
IPC: A61K9/00
Filed: 2021-10-15
Abstract: Described are modified release softgel capsules including a pH dependent shell composition that encapsulated a controlled release fill composition, methods of preparation thereof, and methods of use thereof. The pH dependent shell composition may be characterized in that the delayed release nature of the capsules may be achieved without a separate pH dependent coating or added conventional pH dependent polymers. The softgels provide a dual controlled release platform which facilitates delivery of the active agent to a target location in the gastrointestinal tract and a controlled release profile of the active agent at said target location in the gastrointestinal tract.
Patent EP-4238110-A1 (EP)
Inventor: MAAT STEFAN
IPC: H01B1/02
Filed: 2021-10-29
Abstract: L'invention concerne un fil de bobinage comprenant un noyau conducteur d'aluminium et de carbone (par exemple, des nanotubes de carbone). Le fil de bobinage comprend également une couche isolante sur une surface du noyau conducteur. La couche isolante et le noyau conducteur forment collectivement un fil entièrement isolé d'une bobine associée à un aimant. Le fil de bobinage est configuré pour former, par exemple, la bobine de l'aimant pour l'un quelconque d'un moteur électrique, d'un générateur électrique, d'un transformateur, d'une bobine d'induction ou d'un haut-parleur.
Patent EP-4241042-A1 (EP)
Title: Method and system for determining a similarity or distance measure between ballistic specimens
Inventor: ROBERGE DANNY
IPC: G01B21/20
Filed: 2021-11-04
Abstract: There are described methods and system for determining a similarity or distance measure between a first ballistic specimen and a second ballistic specimen. The method comprises acquiring topographic data from the first ballistic specimen and the second ballistic specimen of at least one region of interest; computing from the topographic data at least one similarity score s for the first ballistic specimen and the second ballistic specimen; determining a non-match probability measure of the similarity score for at least one parameter characterizing a macroscopic and/or microscopic feature of the topographic data, the non-match probability measure associating the first ballistic specimen and the second ballistic specimen to a different source; and correcting the similarity score by determining a corrected similarity score that yields a same value of the non-match probability measure as the similarity score for a reference value of the at least one parameter.
Patent EP-4239872-A1 (EP)
Title: Power converter, and protection method and system
Inventor: CHEN BAOGUO
IPC: H02M7/217
Filed: 2021-09-01
Abstract: This application provides a power converter, a protection method, and a system, and relates to the field of power electronics technologies. The power converter includes a protection circuit, a controller, and a power conversion circuit. The protection circuit includes a first positive temperature coefficient PTC resistor, a first switch unit, and a second switch unit. The power conversion circuit includes a direct current bus, and the direct current bus includes a positive direct current bus and a negative direct current bus. The first switch unit is connected between a power supply and an input end of the power conversion circuit, or is connected in series on the direct current bus of the power conversion circuit. The first PTC resistor is connected in parallel to the first switch unit. The second switch unit is connected in parallel between a positive port and a negative port of the input end of the power conversion circuit, or is connected in parallel between the positive direct current bus and the negative direct current bus. The second switch unit includes a controllable switching tube. The controller is configured to control controllable switching tubes in the first switch unit and the second switch unit. The power converter has high reliability and facilitates miniaturization design.
Patent EP-4225662-A1 (EP)
Inventor: BELIAS WILLIAM P
IPC: B65D65/40
Filed: 2021-11-17
Abstract: Provided herein are packaging systems suitable for storing products, such as food products. The packaging systems are made up of multilayer film constructions that provide controlled release of an active agent at a point in time that is past the manufacturing of the packaging systems but coincides with their functional use ( e.g. , at the food packaging step). The multilayer film constructions have a composition that is sensitive to humidity, which converts the constructions from a barrier to a transmitter of the active agent loaded within multilayer film constructions.
Patent EP-4251333-A1 (EP)
Inventor: ROSS ALLAN
IPC: B05B13/02
Filed: 2021-11-26
Abstract: A liner machine for applying a sealing compound to a can end or lid. The liner machine includes a motor drive dual turret system. The turret system is installed at the top of a table or platform surface and two turrets rotate in opposition directions from one another, simultaneously or independently at same or different times. Each turret includes a plurality of workstations which extend out from each turret facing away from each other. The workstations receive an individual lid, which is delivered via a starwheel from a downstacker to each turret system. Each rotates in a direction that is opposite the direction that its respective turret system rotates, and in a direction that is opposite the direction that the other starwheel rotates. Sealant injectors in the turret systems apply sealant to each lid as the lids rotate around each turret system.
Patent EP-4255333-A1 (EP)
Inventor: CROS FLORENT
IPC: A61B34/30
Filed: 2021-11-30
Abstract: An apparatus and methods of use thereof, the apparatus comprising: a medical device, configured to reside and to be manipulated within a first lumen; and a driving system, configured to manipulate- and/or control- the medical device, via a second lumen. The driving system comprising: a catheter, configured to be inserted into- and to navigate- or to be navigated- within the second lumen; and a driver, configured to travel within the catheter, and to remotely manipulate- and/or control- the medical device residing in the first lumen.
Patent EP-4261315-A1 (EP)
Title: Hot-stamped part
Inventor: YOO BYUNG GIL
IPC: C22C38/38
Filed: 2021-12-08
Abstract: Provided is a hot-stamped part including a base steel sheet, the base steel sheet including an amount of about 0.19 to about 0.25 wt% of carbon (C), an amount of about 0.1 to about 0.6 wt% of silicon (Si), an amount of about 0.8 to about 1.6 wt% of manganese (Mn), an amount of about 0.03 wt% or less of phosphorus (P), an amount of about 0.015 wt% or less of sulfur (S), an amount of about 0.1 to about 0.6 wt% of chromium (Cr), an amount of about 0.001 to about 0.005 wt% of boron (B), an amount of about 0.1 wt% or less of an additive, remaining iron (Fe), and other unavoidable impurities. In an indentation strain rate with respect to an indentation depth of about 200 nm to about 600 nm is observed in a nano indentation test, a number of indentation dynamic strain aging (DSA) is about 26 to about 40.
Patent EP-4266820-A1 (EP)
Inventor: ZENG CHAOJUN
IPC: H04W76/28
Filed: 2021-12-16
Abstract: The present application relates to the technical field of communications. Disclosed are a method and device for communication processing, and a communication device. The method comprises: executing a predetermined operation on the basis of a transmission time of a target physical downlink shared channel (PDSCH), where the target PDSCH is configured as having no target hybrid automatic repeat request acknowledgement (HARQ-ACK) information feedback, or, a feedback delay is found in target HARQ-ACK information corresponding to the target PDSCH; and the predetermined operation comprises at least one of the following: determining whether the target PDSCH corresponds to a nominal HARQ-ACK feedback time unit; determining the moment at which a target media access control layer control element (MAC CE) goes into effect; determining a target HARQ-ACK codebook corresponding to the target PDSCH; determining an application of a first rule; and determining the starting of a target discontinuous reception (DRX) timer.
Patent EP-4265614-A1 (EP)
Inventor: SAITO HIROMASA
IPC: C07D487/04
Filed: 2021-12-16
Abstract: An object of the present invention is to provide a composition that gives a cured product excellent in heat resistance and solvent resistance. The present invention provides a compound represented by the general formula (I) below and having at least one reactive group in a molecule. In the formula, A represents a hydrocarbon ring having 6 carbon atoms; X<sup>1</sup> and X<sup>2</sup> each represent, for example, an aryl group having 6 to 30 carbon atoms and optionally substituted with a reactive group or a group having a reactive group; R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>6</sup>, R<sup>7</sup>, R<sup>8</sup>, and R<sup>9</sup> each represent, for example, a hydrogen atom, a reactive group, or a hydrocarbon group having 1 to 20 carbon atoms and optionally substituted with a reactive group; and R<sup>5</sup> and R<sup>10</sup> each represent, for example, a hydrogen atom, or a hydrocarbon group having 1 to 20 carbon atoms and optionally substituted with a reactive group.
Patent EP-4269451-A1 (EP)
Title: Hydrogenated product of block copolymer, resin composition, and method for producing hydrogenated product of block copolymer
Inventor: SENDA YASUSHI
IPC: C08F8/04
Filed: 2021-12-17
Abstract: A hydrogenated product of a block copolymer containing a polymer block (A) that contains a structural unit derived from an aromatic vinyl compound and a polymer block (B) that contains a structural unit derived from a conjugated diene compound, which satisfies the following requirements: (1) The structural unit derived from a conjugated diene compound of the polymer block (B) has a structural unit derived from butadiene and a structural unit derived from a second conjugated diene compound which is a conjugated diene compound except butadiene. (2) The glass transition temperature is -57°C or lower.
Patent EP-4266422-A1 (EP)
Inventor: SONG JUNG HOON
IPC: H01M4/525
Filed: 2021-12-13
Abstract: The present exemplary embodiments relate to a positive electrode active material and a lithium secondary battery including the same. According to an exemplary embodiment, a positive electrode active material for a lithium secondary battery including a metal oxide particle including nickel, cobalt, manganese and aluminum, and three types of doping elements doped on the metal oxide particle is provided.
Patent EP-4273227-A1 (EP)
Inventor: MENG GANG
IPC: C12N1/21
Filed: 2021-12-29
Abstract: Provided is a method for introducing a point mutation to a BBD29_04920 gene coding sequence in Corynebacterium or improving the expression thereof. The point mutation causes a mutation to the base at position 1560 in the BBD29_04920 gene sequence from cytosine (C) to adenine (A) such that asparagine at position 520 of a coded corresponding amino acid sequence is substituted by lysine. The method can increase fermentation yield of glutamic acid in a strain with the mutation. Also provided are the bacterium generating L-glutamic acid, a nucleic acid and protein comprising the mutation, a recombinant vector and recombinant strain comprising the nucleic acid, and use of these biomaterials in the regulation of the production of L-glutamic acid of a microorganism.
Patent EP-4275268-A1 (EP)
Title: Bipolar induction electric machine
Inventor: IGNJATOVIC DRAGAN
IPC: H02K21/16
Filed: 2021-01-08
Abstract: A bipolar induction electric machine is provided comprising a stator arrangement comprising a plurality of circumferentially arranged stator modules, each stator module comprising a plurality of axially arranged spaced apart stator pole elements fitted with a concentrated armature winding and terminating in an inwardly facing, curved stator pole surface; and a rotor arrangement rotatably and concentrically accommodated within the stator arrangement, the rotor arrangement comprising a plurality of axially arranged rotor modules, each rotor module comprising at least one circumferentially arranged, curved bi-polar member comprising a pair of curved rotor pole elements that are axially displaced on either side of a stationary concentric field exciter coil accommodated within the stator arrangement. The curved rotor pole elements are concentrically arranged relative to the stator pole surfaces so as to define a uniform air-gap therebetween and thus provide a plurality of axially segmented multipolar flux circuits.
Patent EP-4286691-A1 (EP)
Inventor: SHEN ZHIQIANG
IPC: F04D25/08
Filed: 2021-11-05
Abstract: The present disclosure relates to a blowing structure and a fan. The blowing structure includes a main body, a base, a control panel, a second drive member, and a first drive member. The main body is provided with a blowing channel, and the main body is rotatably connected to the base. The control panel is disposed on the main body. The second drive member is disposed in the blowing channel. The first drive member is connected to the main body, and the first drive member is configured to adjust an angle of rotation of the main body with respect to the base. The control panel is electrically connected to the second drive member and the first drive member. In the above blowing structure, since the control panel is disposed on the main body, the second drive member is disposed in a setting area of the main body, and the first drive member is connected to the main body, the wires, which are electrically connected between the control panel, and the second drive member or the first drive member, are routed only in the main body, and do not need to pass through the connection between the main body and the base, so that the length of these wires is reduced, the wire routing is simplified, and the production and assembly costs can be reduced.
Patent EP-4296682-A1 (EP)
Title: Automatic analysis device and method for controlling automatic analysis device
Inventor: NISHIMURA HITOMI
IPC: G01N35/00
Filed: 2021-11-19
Abstract: There is provided an automatic analyzer and a control method of the automatic analyzer capable of coping with various operational environments. A storage unit 127 of an automatic analyzer 101 stores information on a priority of dispensing among various samples and information on a constraint condition of the priority of dispensing of the various samples. A control unit 128 controls, based on the information on the priority and the information on the constraint condition, an operation of a sample disk 102 and a sample dispensing mechanism 104 such that the samples are sequentially dispensed from a sample of a type having a highest priority while following the constraint condition.
Patent EP-4299725-A1 (EP)
Inventor: JEON JONG SOO
IPC: C12N7/00
Filed: 2021-06-15
Abstract: The present application relates to a novel bacteriophage having enterotoxigenic  Escherichia  coli-specific bactericidal effect and an antibacterial composition comprising same, the novel bacteriophage CJ_Eco_20-4 having enterotoxigenic  Escherichia  coli-specific bactericidal effect, and being superbly acid and heat resistant to allow wide use in antibiotics, feed and additives therefor, beverages and additives therefor, disinfectants, detergents, and the like to prevent or treat infectious diseases caused by enterotoxigenic  Escherichia coli.
Patent EP-4316318-A1 (EP)
Inventor: CHEN XIAOLIN
IPC: A47J31/44
Filed: 2021-12-01
Abstract: Disclosed are a locking mechanism for a coffee machine, and a working method therefor. The locking mechanism for a coffee machine comprises an operation plate, a gland assembly and a supporting seat, wherein the gland assembly comprises a pressing block, a rotary lock disk and a guide column; the operation plate is connected to the pressing block; the guide column is longitudinally arranged; the pressing block is in sliding fit with the guide column; a guide connecting position, which is arranged, in an inclined manner, on the rotary lock disk; the pressing block drives the rotary lock disk to rotate by means of the guide connecting position; a lock block is arranged on the rotary lock disk; and a lock groove fitted to the lock block is provided in the supporting seat. The locking mechanism can effectively achieve a locking function, is convenient to operate, has a good sealing performance, and can better meet use requirements of consumers.
Patent EP-4202827-A1 (EP)
Inventor: M S DINESH
IPC: G06T7/00
Filed: 2022-01-10
Abstract: A system (100) for classifying lesions comprising an image providing unit (101) for providing a dual-modal image of an imaging region is provided, the dual-modal image comprising a CT image (10, 10') and a registered PET image (20'), the imaging region including a tissue region of interest comprising a lesion and a reference tissue region. The system further comprises an identifying unit (102) for identifying, in the CT and the PET image, a respective lesion image segment and, in the PET image, a reference image segment. Moreover, the system comprises a normalizing unit (103) for normalizing the lesion image segment in the PET image with respect to the reference image segment, an image feature extracting unit (104) for extracting image feature values from both lesion image segments, and a classifying unit (105) for classifying the lesion based on the extracted values.