baber/WOPTO huggingface dataset:
Patent NZ-603653-A (NZ)
Title: Processes for the preparation of dipyridamole
Inventor: KOKANE DATTATREY
IPC: C07D487/04
Filed: 2011-05-31
Abstract: Disclosed herein is a process for the preparation of dipyridamole which is suitable for large scale commercial production and provides the required product with improved yield and purity. The process comprises reacting 2,6-dichloro-4,8-dipiperidino-pyrimido(5,4-d)pyrimidine with diethanolamine at a temperature between about 100°C and below 130°C. Also disclosed is dipyridamole produced by the process having a purity of up to and greater than 99.9%.
Patent NZ-604175-A (NZ)
Title: Pediatric intramedullary nail
Inventor: GORDON J
IPC: A61B17/72
Filed: 2011-05-04
Abstract: Disclosed is an intramedullary nail system, apparatus and method of implantation. The intramedullary nail (20) is suitable for implantation into paediatric patients. The intramedullary nail (20) is one-piece comprising proximal (22), medial (24) and distal (26) portions. A continuous cannula extends through each of portion (22, 24, 26). The proximal portion (22) has a first longitudinal axis and an end with at least one finger extending parallel the first longitudinal axis. The proximal portion (22) has an internal thread along the cannula extending from the end surface (34) towards the medial portion (24). The proximal portion (22) has first and second linear channels formed through it. The first and second linear channels have respective first and second openings on one side of the proximal portion (22) and a common third opening. The medial portion (24) joins the proximal portion (22) at a bend (32) as viewed in a medial-lateral plane that forms an angle between the proximal portion (22) and medial portion (24) of about 165 degrees. The medial portion (24) has a third linear channel. The third linear channel is non-parallel to either of the first and second channels. The distal portion (26) joins the medial portion (24) at a bend (68) forming an angle of about 175 degrees. The distal portion (26) has fourth and fifth linear channels that are parallel to each other and a sixth linear channel between and non-parallel with said fourth and fifth channels.
Patent NZ-604646-A (NZ)
Title: Novel modified release dosage forms of xanthine oxidoreductase inhibitor or xanthine oxidase inhibitors
Inventor: TANEJA RAJNEESH
IPC: C12N15/09
Filed: 2011-06-15
Abstract: Disclosed herein are dosage forms comprising at least one xanthine oxidoreductase inhibitor or xanthine oxidase inhibitor. More specifically preferred is a modified release pharmaceutical composition comprising immediate release febuxostat beads in an amount ranging from approximately 20% to approximately 40% (w/w) of the total composition weight and delayed release febuxostat beads having a solubility at pH levels greater than or equal to 6.8 in an amount ranging from approximately 60% to approximately 80% (w/w) of the total composition weight, wherein said immediate release beads comprise an inert core in an amount ranging from about 50% to about 55% (w/w) of the weight of the immediate release bead, and an immediate release layer that encapsulates the inert core comprising a mixture of febuxostat and hydroxypropyl methylcellulose in an amount ranging from about 45% to about 50% (w/w) of the weight of the immediate release bead, the ratio of febuxostat to hydroxypropyl methylcellulose ranging from about 1.5 to about 3; and wherein said delayed release beads comprise an inert core in an amount ranging from about 40.5% to about 43% (w/w) of the weight of the delayed release bead, an immediate release layer encapsulating the inert core comprising a mixture of febuxostat and hydroxypropyl methylcellulose in an amount ranging from about 35% to about 40% (w/w) of the weight of the delayed release bead, the ratio of febuxostat to hydroxypropyl methylcellulose ranging from about 1.5 to about 3, a delayed release enteric polymer layer encapsulating the immediate release layer comprising a delayed release enteric polymer in an amount ranging from about 17% to about 20% (w/w) of the delayed release bead, said delayed release enteric polymer comprising a mixture of methacrylic acid copolymer type A and methacrylic acid copolymer type B in a ratio ranging from approximately 0.1 to approximately 0.5, and a plasticizer in an amount ranging from about 1% to about 3% (w/w) of the weight of the delayed-controlled release bead, said plasticizer comprising triethyl citrate.
Patent NZ-613708-A (NZ)
Title: Ratcheting take-up device
Inventor: DANIEL M GRAY
IPC: F16B39/36
Filed: 2013-07-29
Abstract: A take-up device 1 includes a building frame tie-down rod 24 and a housing 26 with an outer bore 17 having a lower inward-curved portion that is frusto-spherical, a plurality of insert segments or collets 2 disposed in the outer bore and contained securely within the housing by the resilient packing 46, each of which has an outer bore-interfacing surface that interfaces with the inward-curved portion of the outer bore of the housing, the outer bore-interfacing surfaces of the plurality of insert segments collectively forming a segmented frusto-spherical surface where the outer bore-interfacing surfaces interface with the outer bore. Each insert segment has a concave inner bore-defining surface and the plurality of concave inner bore-defining surfaces form a generally tubular inner bore into which the rod 24 is inserted so that the rod can be moved up through the inner bore but is caught by the closing surfaces of the collets when it attempts to move back down through the bore, so that the rod is continuously kept under tension by this ratchet action as the wooden frame of the building shrinks and the building settles on the foundations.
Patent NZ-613987-A (NZ)
Title: Substituted aminobutyric derivatives as neprilysin inhibitors
Inventor: GENDRON ROLAND
IPC: C07D471/04
Filed: 2012-02-16
Abstract: The current disclosure relates to biphenyl containing aminobutyric derivatives of formula (I), wherein the various functional group are defined in the specification. The disclosure also relates to methods of manufacture and intermediates, along with pharmaceutical compositions and the use of these compounds as neprilysin inhibitors, which are useful in treating hypertension and heart failure.
Patent NZ-616358-A (NZ)
Title: Method and apparatus for loop filtering cross tile or slice boundaries
Inventor: HUANG YU-WEN
Filed: 2013-01-30
Abstract: Disclosed is a method of loop filter processing for boundary pixels across a block boundary. The boundary pixels comprise first pixels on a first side (210) of the block boundary and second pixels on a second side (220) of the block boundary. The method comprises receiving reconstructed video data associated with a picture from a media or a processor; determining a value of a cross-slice loop filter flag or a cross-tile loop filter flag corresponding to the slice or tile respectively; applying the loop filter processing to the boundary pixels across the slice boundary or tile boundary according to the value of the cross-slice loop filter flag or the cross-tile loop filter flag. The reconstructed video data is partitioned into slices or tiles, and a slice boundary or a tile boundary of a slice or tile is aligned with one block boundary. The loop filter processing depends on a first parameter for the first pixels inside the slice or tile and a second parameter for the second pixels outside the slice or tile.
Patent NZ-623329-A (NZ)
Title: System and method for activating article protection features of a carton
Inventor: DISRUD JEFF A
IPC: B65B49/14
Filed: 2012-10-19
Abstract: A system and method for activating a series of article protection features formed in product cartons in which a series of articles have been packaged includes an actuating assembly mounted along a path of travel for the cartons. The actuating assembly will include a series of actuating elements that are selectively moved into engagement with the article protection features of the cartons. The article protection features are urged into the cartons, between the articles therein and into positions engaging and supporting the articles.
Patent NZ-631333-A (NZ)
Title: Supply packs and methods and systems for manufacturing supply packs
Inventor: POTTER JEFFREY J
IPC: B64D17/00
Filed: 2013-03-15
Abstract: An aerial distribution system for deploying items is disclosed. The system comprises a bulk shipping container having a plurality of deployment boxes within. Each deployment box contains at least one item of cargo. A plurality of tethers, each coupling a deployment box to the bulk shipping container, are provided. A freefall retarding device, such as a parachute, is coupled to the bulk shipping container. A method of deploying cargo from a vehicle, such as an aircraft, is also provided. The method includes expelling a bulk shipping container from a vehicle over a location of deployment. Subsequent to deployment, the bulk shipping container releases the plurality of deployment boxes which, in turn, release the cargo.
Patent NZ-715151-A (NZ)
Title: Modulators of growth hormone receptor
Inventor: FREIER SUSAN M
IPC: A61P5/08
Filed: 2014-07-01
Abstract: The present embodiments provide methods, modified antisense oligonucleotide compounds, and compositions for treating, preventing, ameliorating a disease associated with excess growth hormone using modified antisense compounds oligonucleotides targeted to growth hormone receptor (GHR).
Patent NZ-715357-A (NZ)
Title: Sliding sleeve attachment for an injection device
Inventor: BITAR AHMAD
IPC: A61M5/178
Filed: 2014-06-11
Abstract: There is provided an injection device comprising a housing adapted to receive a syringe having a discharge nozzle, the syringe being moveable in the housing on actuation of the injection device along a longitudinal axis from a retracted position in which the discharge nozzle is contained within the housing and an extended position in which the discharge nozzle of the syringe extends from the housing through an exit aperture at a distal end of the device, a sliding component which extends, when in a first position, from the aperture, and is movable towards the housing into a second, retracted, position, wherein the sliding component comprises, at its distal end, a removable contact element. It can be difficult for a user to position the sliding sleeve of an injection device at the correct angle against tissue. Ensuring the sliding sleeve is forced against the tissue at the correct angle and held sufficiently stable is important to ensure reliable operation, and this can be aided by the provision of the removable contact element.
Patent NZ-720520-A (NZ)
Title: Tagged chimeric effector molecules and receptors thereof
Inventor: RIDDELL STANLEY
IPC: C07K16/30
Filed: 2014-12-22
Abstract: The present disclosure relates to tagged chimeric effector molecules and receptor molecules thereof for genetically engineering a host cell, wherein the recombinant host cell can be identified, isolated, sorted, induced to proliferate, tracked or eliminated using the tag. An exemplary receptor molecule is a chimeric antigen receptors (CARs) having an extracellular domain comprising a binding domain for a target, a hinge region and a tag cassette, a hydrophobic portion as a transmembrane domain and, an intracellular part with an effector domain. An exemplary target is CD19, an exemplary tag is a Step-tag. T cells recombinantly modified for expression of such molecules may be used in adoptive immunotherapy.
Patent NZ-720984-A (NZ)
Title: Fluid transmission coupler with rear chamber fed by oblique pipe
Inventor: ALLEVI MATTEO
IPC: F16K15/14
Filed: 2014-11-10
Abstract: Fittings which may be rapidly coupled to one another to connect a fluid feed, by means of rigid pipes or flexible hoses, are frequently required for fluid transmission for example in operating machines and hydraulic equipment. The known quick coupling fittings usually consist of two couplers, named male and female, which are fastened to respective pipes to be joined and which can be coupled together by screwing or by snapping. The currently marketed fluid transmission solutions show that the coupling between the male coupler and the female coupler is not always very easy with effort increasing incrementally as the residual pressure present in the circuit increases. There is provided a fluid transmission coupling assembly comprising a hydraulic feeding block, a female coupler inserted in the hydraulic feeding block, and a male coupler adapted to be coupled with said female coupler. The block includes at least one hydraulic line and a draining line, and a lever integral with a cam adapted to relieve the pressure from a chamber inside the female coupler and adapted to uncouple the male coupler from the female coupler. The female coupler comprises a pressure relief valve which puts said chamber into communication with the draining line. The female coupler comprises a seal adapted to close a calibrated communication pipe. The seal is located between the chamber and the hydraulic line. The calibrated communication pipe is contained in a body of the female coupler external to the chamber with respect to the axis of the assembly, thus generating a pressure difference between the hydraulic line and the chamber. The at least one hydraulic line, in coupled configuration of the assembly, is in fluid connection with the said male coupler through multiple openings provided in the body of the female coupler. The multiple openings are arranged around the axis of the assembly with an oblique axis with respect to the axis of the assembly. The calibrated communication pipe is arranged external to said chamber and having an oblique axis with respect to the axis of the assembly. The seal has an annular shape, and comprises a non-deformable portion and a deformable portion. The deformable portion bends towards the inside of the chamber when a given nominal pressure is reached, thus determining the entrance of the pressurized fluid in the chamber of the hydraulic line. The deformable portion returns to its initial position thus obstructing the passage of fluid when the pressure returns under said nominal pressure.
Patent NZ-721686-A (NZ)
Title: Device and method for sleep apnoea treatment
Inventor: GERSCHMAN JACK
IPC: A61F5/56
Filed: 2014-12-18
Abstract: A sleep apnoea treatment device 10 comprising a mouthpiece 12 including a vestibular locator 14 and an airway conduit 16, the vestibular locator 14 being adapted for positioning in the mouth vestibule of a user interposed between the lips and teeth of the user, wherein the vestibular locator 14 is a flange having an inner surface and an outer surface, the vestibular locator 14 supporting the airway conduit 16 in place relative to the user’s mouth with the airway conduit 16 extending between the lips of the user whereby the airway conduit 16 maintains fluid communication of the mouth vestibule with ambient air to facilitate the user breathing the ambient air through the airway conduit 16, wherein an arcuate bite platform 42 extends from an inner surface of the vestibular locator 14 and extends either side of the airway conduit 16, and the airway conduit 16 extends through the flange 44 and through the arcuate bite platform 42; the device including a formation for engagement with a lower jaw of the user to retain the lower jaw in a forward position and the device further including an abutment for abutting the upper jaw such that force from retaining the lower jaw is transferred to the upper jaw; and wherein the device includes a removable mask portion through which the airway conduit extends, the mask portion including a flexible flap which is able to be resiliently snapped forward to facilitate fitment of the device and is able to be snapped rearward to abut the user’s face, holding the upper and lower jaws together, thereby preventing dropping of the lower jaw .The sleep apnoea treatment device is simple, relatively inexpensive, non-customised, self-adaptable and self-fitting.
Patent NZ-723858-A (NZ)
Title: Anti-human ox40l antibodies, uses & methods
Inventor: CAMPBELL JAMIE
IPC: A61K39/395
Filed: 2015-03-03
Abstract: The present invention relates to anti-human OX40L antibodies, new medical uses and methods. The antibodies have pharmaceutical applications to inflammatory disease, autoimmune diseases, and to diseases in which OX40 is upregulated.
Patent NZ-724042-A (NZ)
Title: High pressure fluid spray nozzle incorporating a flow controlled switching valve
Inventor: ANDERSEN COLTON
IPC: F16K11/07
Filed: 2015-02-18
Abstract: A nozzle assembly comprises a hollow nozzle body having a central bore and a plurality of ports extending through the body from the central bore; and a switching valve cartridge disposed in the central bore that directs fluid flow to ports upon application of fluid flow above a predetermined threshold to the inlet and direct fluid flow to different ports upon fluid flow having subsequently dropped below the predetermined threshold and then exceeding the predetermined threshold. The cartridge comprises a cylindrical cartridge case having a front portion and a cup shaped rear portion, a cylindrical poppet slidably disposed within the cup shaped rear portion of the cartridge case, and a biasing member within the cartridge case between the front portion of the case and the poppet urging the poppet away from the front portion of the cartridge case.
Patent NZ-724830-A (NZ)
Title: Hydropyrolysis of biomass-containing feed stocks
Inventor: LARRY G FELIX
IPC: C10B51/00
Filed: 2014-09-11
Abstract: Disclosed herein a process for the pre-treatment of low cost biomass feedstocks containing municipal solid waste (MSW), algae, or lemna and subsequent hydropyrolysis to produce high value liquid hydrocarbon fuels, wherein the process comprises: (a) devolatilizing the feedstock in a pre-reactor vessel containing hydrogen and a solid bed material selected from the group consisting of a pretreating catalyst, a sorbent, a heat transfer medium, to produce a pre-reactor vapour stream; (b) hydropyrolyzing at least a portion of the pre-reactor vapour stream in a hydropyrolysis reactor vessel containing hydrogen and a deoxygenating catalyst, producing a hydropyrolysis reactor output comprising at least one non-condensable gas, a partially deoxygenated hydropyrolysis product and char particles; (c) removing substantially all of the char particles from the hydropyrolysis reactor output to provide a purified hydropyrolysis reactor vapour stream having a reduced char content; (d) hydroconverting at least a portion of the purified hydropyrolysis reactor vapour stream in a hydroconversion reactor vessel containing hydrogen and a hydroconversion catalyst, producing a hydroconversion reactor output; and (e) recovering a substantially fully deoxygenated hydrocarbon liquid and a gaseous mixture from the hydroconversion reactor output.
Patent NZ-724908-A (NZ)
Title: Immunological compositions containing attenuated histophilus somni
Inventor: KOLANDER TAMMY
IPC: A61K39/00
Filed: 2015-03-25
Abstract: This disclosure provides attenuated Histophilus somni strains, compositions comprising same, and methods of production and use thereof. The attenuated strains may express lower or no levels of various virulence-associated genes, relative to the corresponding pathogenic bacteria Advantageously, the attenuated Histophilus somni strains may be administered orally, intranasally, intra-tracheally, or subcutaneously.
Patent NZ-725228-A (NZ)
Title: Hydrokinetic energy conversion system and use thereof
Inventor: HOLM ANDERS
IPC: F03B13/26
Filed: 2015-03-18
Abstract: A hydrokinetic energy conversion system (1) comprising a turbine device (2) comprising a rotor (3) displaying a rotational axis (O), which turbine device is arranged to operate with the rotational axis in an inclined orientation vis-à-vis an incoming body of water (W), and which rotor comprises a blade (10) which is arranged to interact with the incoming body of water such that rotational energy is imparted to the rotor. The blade comprises a first, convex surface (12), a second, concave surface (13) and a free, distal edge (E) where the first surface and the second surface meet. The curvature of the second surface, when viewed in a plane orthogonal to the rotational axis, is such that a maximum depth (Dmax) of the second surface, when measured from a straight line intersecting the rotational axis and the distal edge, is at least 35% of the distance between the rotational axis and the distal edge. The problem of the prior art is that those turbines had a lower efficiency compared to the theoretical efficiency of the present invention. In particular the blade geometry of this invention may improve efficiency of energy in to electricity out.
Patent NZ-731583-A (NZ)
Title: System for releasable coupling of a hole saw to a drill arbor
Inventor: BOSKE RICHARD ALEXANDER
IPC: B23B51/04
Filed: 2015-11-09
Abstract: The present invention relates to a system for releasable coupling of a hole saw (55) to a drill arbor (5). The system comprises an elongate drill arbor (5) configured at a first end to be clamped in a drill chuck of a drill, and a hole saw adapter (3) provided with a longitudinal bore (9) in which the drill arbor (5) can be received so that an inner surface of the longitudinal bore (9) of the hole saw adapter (3) is mounted slidably on an outer surface of the drill arbor (5) in the longitudinal direction of the drill arbor (5). The drill arbor (5) comprises an actuator member (25) and at least one retaining element (27) co-acting therewith. The inner surface of the longitudinal bore (9) of the hole saw adapter (3) is provided with a recess (49) into which the retaining element (27) of the drill arbor can protrude. This invention addresses the issues regarding saw dust entering the internal mechanisms of hole saw drill arbors by having the possible dust entry points covered by the hole saw adapter and the operating element’s collar. This invention also addresses the issue of the unintentional release of the hole saw adapter this issue is solved by the actuator being held down by the operating element thus blocking the movement of the retaining elements. The retaining elements also has the added benefit of being able to accommodate small diameter hole saws unlike the pivot latch system where only relatively large hole saw diameters are able to be mounted.