baber/WOPTO huggingface dataset:
Patent CA-2190682-A1 (CA)
Title: Process for preparing n-benzyl indoles
Inventor: BACH NICHOLAS JAMES
IPC: C07D401/10
Filed: 1996-11-19
Abstract: A process for producing a compound of the formula    (I) in which R1 is hydrogen, halo, C1-4  alkyl, C1-4; alkoxy, nitrile, optionally protected carboxy, optionally protected tetrazolyl, trihalomethyl, hydroxy-C1-4 alkyl, aldehyde, -CH2Z, -CH=CH-Z or -CH2CH2Z where Z is optionally protected carboxy or optionally protected tetrazolyl; R~ is halo, nitrile, an optionally protected acid group or -CONR7R8 where R7 and R6 are hydrogen or C1-4 alkyl; R4 is C2-4 alkyl, or C2-4 alkyl substituted by -CONR7R8 or an optionally protected acid group; R5 is       or   where W is -CH=CH-, -CH=N-, -N=CH-, -O- or -S-, R9 is hydrogen, halo, C1-4, alkyl, C1-4 alkoxy or trihalomethyl, and R10 is hydrogen, C1-4 alkyl, C2-6 alkenyl, C3-6 cycloalkyl or C1-4 alkyl-C3-6  cycloalkyl; R6 is hydrogen or C1-4 alkyl; X is -O-(CH2)nCR11R12-, -CR11Rl2-, -CR11R12- (CH2)n.CR13R14- or -CR11=CRl2- where R11, R12, R13 and R14 are each hydrogen or C1-4 alkyl, and n is 0, 1 or 2; and Y is -O-CR15R16-,  -CR15=CR16- or -CR15R16. CR17R18- where R15, R16, R17 and R18 are each hydrogen or C1-4 alkyl; or a salt thereof, comprising the step of reacting a compound of the formula       (II) with a compound of the formula       (III) to form a compound of the formula       (IV) wherein R2a is selected from the groups recited above for R2, or R2a-X- is a protected hydroxyl group, and Z is a group of formula -Y-R5 recited above, or a group that can be converted into a group of said formula -Y-R5. Intermediates of formula IV and composition containing substantially optically pure enantiomers of Formula (I) are included within the scope of the invention.
Patent CA-2192211-A1 (CA)
Inventor: SEMPLE JOSEPH E
IPC: A61K38/05
Filed: 1995-06-19
Abstract: L'invention concerne des aldéhydes peptidiques constituant des inhibiteurs puissants et spécifiques de la thrombine, leurs sels pharmaceutiquement acceptables, des compositions pharmaceutiquement acceptables de ceux-ci, et leurs procédés d'utilisation en tant qu'agents thérapeutiques pour les états pathologiques chez les mammifères caractérisés par une thrombose anormale.
Patent CA-2193578-A1 (CA)
Inventor: INOMATA KOHEI
IPC: A61K31/137
Filed: 1996-12-20
Abstract: There is disclosed a multidrug resistance inhibitor for overcoming a multidrug resistance of cancer, or an agent for enhancing the activity of anti-cancer agents, which comprises as an active ingredient a compound of formula (I) or a pharmaceutically acceptable salt thereof:     (see fig. I)            (I) wherein n is an integer of 5 to 12, R1 and R2 are each independently benzyl, of which a phenyl ring may be substituted by 1 to 5 substituents selected from hydroxy, (C1-C4)alkyl, (C1-C4)alkoxy and halogen, and/or by methylenedioxy, with the proviso that R1 and R2 are simultaneously not a compound of formula (II).                 (see fig. II)        (II)
Patent CA-2195009-A1 (CA)
Title: Control device for selectively limiting stroke of swing actuator for implement mid-mounted pivot tongue
Inventor: STEPHENSON ROGER DALE
IPC: A01D67/00
Filed: 1997-01-13
Abstract: An implement includes a mid-mounted pivot tongue that is movable in a normal range of movement when the implement is working and to a transport position for towing the implement endwise when the implement is to be transported. Two embodiments of a stroke control device are provided and each acts to limit the stroke of a tongue-swing hydraulic actuator to operate for swinging the tongue through its operating range during normal operation of the implement, with each stroke control device being selectively operable to a stroke-freeing position permitting the actuator to operate through its entire stroke for moving the tongue beyond its operating range to a transport position. The stroke control devices and the tongue include cooperating structure for locking the tongue in its transport position.
Patent CA-2195833-A1 (CA)
Title: Bearing device for vertical rotating machine
Inventor: KISHIKAWA TADAHIKO
IPC: F16C33/10
Filed: 1997-01-23
Abstract: A bearing device for supporting a rotating shaft substantially arranged in a vertical direction in a vertical rotation machine is disclosed. The bearing device enables the vertical rotation machine to operate in a stable and contamination-free condition by preventing leakage of lubricant as well as to decrease the lubricant consumption. The bearing device comprises a roller bearing for supporting the rotating shaft and a labyrinth seal provided below the bearing. An oil dam is provided at a bottom portion of a bearing chamber to surround the sealing. An oil suction pipe for discharging lubricant from the oil dam, a sealing gas supply passage for supplying sealing gas into the bearing chamber from below by way of the sealing, and a sealing gas vent port opening at an upper area of the bearing chamber are provided.
Patent CA-2197598-A1 (CA)
Title: Fire-retardant polyurethane systems
Inventor: CHAIGNON JOEL
IPC: C08K3/22
Filed: 1997-02-14
Abstract: A storage-stable moisture-curing one-component fire-retardant polyurethane system, useful as adhesive, sealant or coating material, comprising at least one hydrated mineral having a water-content of less than 0.1%  and being treated with a moisture-reactive compound, and at least one binder on isocyanate basis. Such PU-systems preferably further comprise at least one phosphorus-containing compound, most preferably a phosphorus-containing plasticizer, which is preferably halogen-free.  The binder on isocyanate basis has preferably an isocyanate content in the range of from 0.01 to 10 % by weight referred to the total weight of the system.
Patent CA-2198580-A1 (CA)
Title: Combination therapy to treat osteoporosis
Inventor: MACLEAN DAVID B
IPC: A61K31/138
Filed: 1997-02-26
Abstract: The present invention provides a pharmaceutical composition for treating or preventing osteoporosis in a mammal in need of treatment which composition comprises an effective amount of a compound of formula I     (see fig.I) wherein R1 and R2 may be the same or different provided that, when R1 and R2 are the same, each is a methyl or ethyl group, and , when R1 and R2 are different, one of them is a methyl or ethyl group and the other is hydrogen or a benzyl group; or a pharmaceutically acceptable salt thereof; together with a bone resorption inhibiting polyphosphonate, or with parathyroid hormone.
Patent CA-2200210-A1 (CA)
Inventor: MISSBACH MARTIN
IPC: C07D487/04
Filed: 1995-09-08
Abstract: Pyrrolo[2,3-d]pyrimidines de formule (I) dans laquelle R¿1?, R¿2? et R¿3? sont tels que définis dans la description. Ces composés possèdent des propriétés pharmacologiques utiles; ils sont notamment efficaces en tant qu'inhibiteurs de la tyrosine kinase pp60?c-src¿ et sont préparés d'une manière connue en soi.
Patent CA-2203021-A1 (CA)
Inventor: SMEDAL ARNE
IPC: B63B27/34
Filed: 1995-11-03
Abstract: An arrangement in a load-ing/unloading buoy for use in shallow waters, wherein the buoy (1) is arranged for introduction and releasable securement in a downwardly open receiving space in a floating vessel, the buoy comprising a bottom-anchored centre member (2) for the passage of medium from or to a transfer line (25) which is coupled to the underside of the centre member (2), and an outer member (4) which is rotatably mounted on the centre member to allow turning of the vessel about the centre member when the outer member is secured in the receiving space. The buoy is provided with a bottom support structure (15) which is connected to the centre member (2) of the buoy and arranged for support of the buoy at the sea bed (16) when it is not in use, and to the centre member of the buoy there are connected a number of mooring lines (21) extending outwards from the buoy (1) a substantial distance along the sea bed (16) and having an inherent elasticity allowing raising of the buoy from the sea bed.
Patent CA-2203845-A1 (CA)
Inventor: EPWORTH RICHARD EDWARD
IPC: G02F1/21
Filed: 1997-04-28
Abstract: A control system for an etalon arrangement 4, in an optical transmission system involves applying a dither to a laser 1 upstream of the arrangement, monitoring the output of the arrangement, and using a control means 3 to lock the laser frequency to the etalon arrangement response, or vice versa. The control means operates on the basis of a ratio of derivatives of the monitored output with respect to wavelength, to enable locking to a point on the response curve, independent of power variations.
Patent CA-2205321-A1 (CA)
Title: Patient-worn energy delivery apparatus
Inventor: GLEGYAK JOHN A
IPC: A61N1/39
Filed: 1997-05-14
Abstract: The present invention provides for a patient-worn energy delivery apparatus for imparting electrical therapy to the body of a patient responsive to an occurrence of a treatable condition. The apparatus includes a voltage converter for converting electrical energy from an initial voltage to a final voltage at a plurality of charging rates, and a defibrillator electrically coupled between the converter and the patient and having an energy reservoir for receiving the electrical energy. The defibrillator produces preshaped electrical pulses such as defibrillation pulses and cardioversion pulses. The apparatus additionally includes an energy delivery controller electrically coupled to the patient and the converter and the defibrillator. The controller causes the converter to provide the electrical energy to the defibrillator at a specific charging rate in response to an energy level in the reservoir. The apparatus may include a plurality of electrodes interposed between the defibrillator and the patient and each electrode preferably has an impedance reducing means contained therein. One embodiment of the apparatus may include a H-bridge to produce a positive-going pulse segment and the negative-going pulse segment within the biphasic exponential signals.
Patent CA-2208832-A1 (CA)
Inventor: HEWKA LEDA
IPC: A61F2/34
Filed: 1997-06-25
Abstract: A plug is provided for securing two components of an orthopedic implant where at least one of the components is formed of material softer than the material of the plug.      In a preferred embodiment the components comprise concentric cups rotatable with respect to one another about an axis. The components are fixable using a plug to prevent rotation of the components with respect to each other. The invention is preferably used with an acetabular shell and liner of a hip implant wherein the shell is comprised of metal material and the liner is comprised of a polymer or other similar soft material.      The plug has a serrated head and a distal lip or anchoring edge to provide securement at more than one location along the length of the plug. The plug is insertable into a common opening defined by aligned recesses or openings of the two components of the implant.
Patent CA-2208897-A1 (CA)
Title: Roll stand for strip rolling
Inventor: MUENKER JOCHEN
IPC: B21B27/02
Filed: 1997-06-26
Abstract: A roll stand with work rolls supported by a back-up roll either directly or through an intermediate roll, particularly work rolls which are axially displaceable in opposite directions, wherein at least one of the rolls of the roll stand is constructed with varying resilience over the length thereof, particularly with a greater flattening behavior in at least a portion thereof. For this purpose, at least one of the rolls has in the area between the roll neck and the outer surface of the roll at least one notch extending concentrically about the axis.
Patent CA-2214288-A1 (CA)
Title: Process for the preparation of 1-acyl-4-arylpiperidines
Inventor: BRIEDEN WALTER
IPC: C07D211/82
Filed: 1997-08-29
Abstract: 1-Acyl-4-arylpiperidines of the general formula:   (see formula I) wherein R1 is an aryl group optionally substituted by one or more C1-6-alkyl groups, C1-6-alkoxy groups, benzyloxy groups or C1-6-alkylthio groups and/or one or more fluorine atoms, and R2 is a C1-6-alkyl group, a C1-6-alkoxy group, an optionally substituted aryl group, alkylaryl group or a benzyloxy group optionally substituted on the phenyl radical, are prepared by reacting an arylmagnesium halide with a 1-acylpyridinium halide, obtainable from pyridine and an acyl halide, in the presence of a copper compound to give the corresponding 1-acyl-4-aryl-1,4-dihydropyridine, and hydrogenating the latter. The 1-acyl-4-arylpiperidines are intermediates in the synthesis of pharmaceutical active ingredients, for example, of neurokinin receptor antagonists.
Patent CA-2217765-A1 (CA)
Title: Tomato string stem fruit cluster support device
Inventor: PABLO GERARDO
IPC: A01G9/12
Filed: 1997-12-01
Abstract: Our invention relates to a "TOMATO STRING STEM FRUIT CLUSTER SUPPORT DEVICE." A particular application of the invention is for the device to be attached to the String used in Greenhouse/Hothouse/Hydroponic growing operations, in particular the invention would be attached and secured to a string that holds the Tomato vine and when anchored into place would support the Tomato Fruit Cluster Stem from breaking of the Main Vine due to its enormous heavy weight. Because of the nature of Greenhouse/Hothouse/Hydroponic grown tomatoes whereby the Tomato Plant is actually a vine that stretches over 25 ft. in length, the tomato plant is elevated and suspended from the ground up to the ceiling by a String Support to the designated height of the greenhouse ceiling. When the plant is then elevated and made to stand up by way of the string, the Tomato Fruit Cluster then becomes a burden in terms of weight considerations. When the Tomato Fruit Clusters are growing and before reaching their maximum growth and ripening process their weight becomes their undoing. The fruit clusters become top heavy and it then shears the tomato cluster stem from the main vine thereby causing it to break. When such break occurs the plant is then prone to disease causing the plant to die prematurely before its maximum growing lifespan. The main intention and purpose of the invention are to cover such problem areas.
Patent CA-2217939-A1 (CA)
Title: Well cementing plug assemblies and methods
Inventor: LAUREL DAVID F
IPC: E21B33/16
Filed: 1997-10-10
Abstract: An improved well cementing plug assembly adapted to be connected to a string of drill pipe or a circulation tool for use in a pipe during the cementing of the pipe in a well bore is provided.  The top and bottom plugs are selectively releasable by activating balls dropped into the plug assembly.          Different sizes of plugs can be used utilizing the same inner tubes and other assembly parts, and the top plug slides on its inner tube when a pressure differential is exerted on it thereby insuring a seal between the top and bottom plugs when the plugs are landed on a float shoe or the like.
Patent CA-2219856-A1 (CA)
Title: Process for transitioning between incompatible polymerization catalysts
Inventor: RENOLA GARY THOMAS
IPC: C08F2/42
Filed: 1996-05-30
Abstract: This invention relates to a process for transitioning between polymerization catalyst systems which are incompatible with each other. Particularly, the invention relates to a process for transitioning from an olefin polymerization reaction utilizing a traditional Ziegler-Natta catalyst system to an olefin polymerization reaction utilizing a metallocene catalyst system.
Patent CA-2222434-A1 (CA)
Title: Louver assembly with multi-position louver adjusting control rod having clamping connecting arms
Inventor: RICCI FERNANDO
IPC: E06B7/09
Filed: 1997-11-26
Abstract: A louver assembly is comprised of two or more louvers, each of the louvers having pivot connections at opposed ends thereof, with. the pivot connections pivotally securing the louvers between opposed stiles of a shutter f rame for pivot ing mot ion of the louvers in the frame. Each louver has a connector secured to a common longitudinal side edge thereof. Each connector has a cavity with a connector rod extending thereacross and extending co-extensively to the longitudinal axis of its associated louver. Each connector rod has at least one engageable rib on an outer surface thereof. A control rod is provided with two or more transverse connecting arms each having a connecting end recess. Each end recess has a plurality of indentations formed at a predetermined location in a curved clamping inner face thereof for receiving the rib of a respective connector rod captive therein by clamping pressure of the connecting arms about the connector rod to angulate the louvers at a desired angle.
Patent CA-2223537-A1 (CA)
Title: Enhanced position calculation
Inventor: POPPE MARTIN C
IPC: G01S1/04
Filed: 1996-06-06
Abstract: A system for enhancing the accuracy of a radio position fix, utilizing computational techniques including neural networks (100), mapped grid coefficients as input to a set of simultaneous or differential equations, and table lookup of correction coefficients for known low accuracy positions. Receiver array (102) synchronization, such that all system elements in a particular coverage area will obtain a time reference appropriate for time of flight radio location measurements, is disclosed. Techniques to enhance the accuracy of position fix references, which are located in a coverage area, as well as a mobile reference carried by a search team are disclosed. A  system for guiding a search team to an unknown positioned transmitter (103) that is located within a structure is taught using the present techniques, as well as training a central computing unit (100) by using actuarial data, so that multi-path errors resulting from fixed or mobile obstacles may be reduced.
Patent CA-2226205-A1 (CA)
Title: Side load compensating airspring for a vehicle suspension
Inventor: CRABTREE MICHAEL L
IPC: F16F9/04
Filed: 1998-01-05
Abstract: A telescopic strut for a vehicle suspension of the airspring type with a flexible sleeve forming a chamber portion and a rolling lobe portion. The chamber portion is attached to a tilted closure and the rolling lobe portion of the airsleeve is attached to a piston that is transversely moved which introduces a shear force into the airsleeve and increases a surface area on an upward tilted side of the sleeve so as to provide side load compensation and where the axial length of the rolling lobe is substantially equalized to enhanced flexural life.
Patent CA-2226427-A1 (CA)
Title: Extraction of triglycerides from microorganisms
Inventor: LIDDELL JOHN MACDONALD
IPC: C12N1/06
Filed: 1996-07-16
Abstract: Oil is extracted from oil containing microorganisms by disintegrating the microorganisms and contacting them in the presence of a water content of at least 70 % by weight of that originally present in the cellular material with a water immiscible solvent for the oil, separating the solvent from the microorganisms and recovering the oil from the solvent.
Patent CA-2230970-A1 (CA)
Title: Inhibiteur specifique de cyclo-oxygenase 2 et agent anti-inflammatoire
Inventor: HASHIMOTO SHUSUKE
IPC: A61P43/00
Filed: 1996-09-11
Abstract: L'invention concerne un inhibiteur spécifique de cyclo-oxygénase 2, dont l'élément actif est un acide 2-(2,6-dichloro-4-hydroxyanilino)-phénylacétique représenté par la formule (1) ou bien un sel de cet acide. L'invention concerne également un agent anti-inflammatoire ayant la même composition. Le composé considéré inhibe spécifiquement la cyclo-oxygénase 2, et non pas l'activité de la cyclo-oxygénase 1. Ainsi, son utilisation est rarement accompagnée d'un effet secondaire sous la forme de troubles gastro-intestianux. Il constitue en outre un produit sûr de faible toxicité.
Patent CA-2231209-A1 (CA)
Title: Preparation of precipitated polyamide powders of narrow particle size distribution and low porosity
Inventor: WILCZOK NORBERT
IPC: C08J3/14
Filed: 1998-03-03
Abstract: Disclosed is a process for preparing polyamide powder having a narrow particle size distribution and a low porosity.  The process comprises,  (1) dissolving a polyamide having at least 10 C atoms in its monomer in a C1-C3 alcohol under pressure to produce a solution at 130-165°C,  (2) cooling the solution without precipitation until nucleation takes place and maintaining the temperature constant for awhile,  (3) further cooling the solution until super saturation results, (4) then precipitating particles of the polyamide at a constant temperature to obtain a suspension and (5) drying the polyamide particles.  The polyamide powder so-obtained is useful, for example, as a coating material.
Patent CA-2235905-A1 (CA)
Title: Olefin polymerization catalysts, transition metal compounds, processes for olefin polymerization, and .alpha.-olefin/conjugated diene copolymers
Inventor: MITANI MAKOTO
IPC: C08F210/02
Filed: 1998-04-24
Abstract: The invention provides olefin polymerization catalyst exhibiting excellent polymerization activities, a process for olefin polymerization using the catalyst, a novel transition metal. compound useful for the catalyst, and an .alpha.-olefin/conjugated diene copolymer having specific properties.  The olefin polymerization catalyst of the invention comprises (A) a transition metal compound of formula (I) or (II), and (B) an organometallic compound, an oranoaluminum oxy-compound or an ionizing ionic compound.  The novel transition metal compound of the invention is a compound of formula (I) wherein M is a transition meal atom of Group 3 or 4 of the periodic table; m is an integer of 1 to 3; R1 is a hydrocarbon group, etc.; R2 to R5 are each H, a halogen, a hydrocarbon group, etc.; R6 is a halogen, a hydrocarbon group, etc.; n is a number satisfying a valence of M; and X is a halogen, a hydrocarbon group, etc.     (see fig. I)      (see fig. II)
Patent CA-2236597-A1 (CA)
Title: Cellular polyurethane elastomers
Inventor: SCHMIDT ANDREAS
IPC: C08G18/38
Filed: 1996-12-11
Abstract: A cellular polyurethane elastomer is produced by reacting: (a) an isocyanate component comprising methylenebis(phenyl isocyanate)(MDI), tolylene diisocyanate (TDI), or both thereof, with (b) compounds with at least two isocyanate-reactive hydrogen atoms and (c)4,4'-methylenebis (3-chloro-2,6-dialkylaniline)or a mixture of 4,4'-methylenebis (3-chloro-2,6-dialkylaniline)with one or more aromatic, aliphatic or cycloaliphatic diamines as chain extending agents, possibly together with an additional polyol and (d) a blowing agent, in the presence of usual catalysts and other optional additives.      These cellular polyurethane elastomers are useful to produce moulded bodies which are subjected to high dynamic and thermal stresses.
Patent CA-2236688-A1 (CA)
Title: Device and method of supplying from an ac source
Inventor: ASSOW BENGT
IPC: H02M7/06
Filed: 1996-11-01
Abstract: In an arrangement for supplying energy from an a.c. voltage source that includes a rectifier bridge (D1) and a converter (TR1, D5, C4), an inductor means (L1) is connected between a first output terminal on the rectifier bridge and a valley-fill circuit (10) that includes at least two capacitors (C1, C2). The converter includes a transformer (TR1) having a primary winding which together with a controllable switch means (SW1) is included in a loop that extends from a second output terminal on the rectifier bridge to the interconnection junction between the inductor means and the valley-fill circuit (10). When the absolute value of the source voltage is greater than or approximately equal to a highest intermediate voltage including the voltage across at least one capacitor in the valley-fill circuit, energy is supplied from the source to the inductor means and to the valley-fill circuit. Energy is then supplied to the converter from the source via the inductor means and in parallel from all capacitors (C1, C2) that have said highest intermediate voltage, wherein the amount of source energy supplied is dependent on the voltage (VC3) across the input of the converter.