baber/WOPTO huggingface dataset:
Patent AU-1047699-A (AU)
Title: Haptoglobin assay
Inventor: ECKERSALL PETER DAVID
IPC: G01N33/72
Filed: 1998-11-12
Abstract: The present invention relates to a haptoglobin assay of the type wherein the level of haptoglobin in a sample to be tested is determined by measuring the peroxidase activity of haptoglobin/haemoglobin complex. The assay employs at least one reagent for reducing a peroxidase effect due to any albumin or any other protein(s) present in the sample. The reagent may be selected from a) a reducing agent effective against disulphide bonds; b) a protein binding inhibitor and/or c) a chaotropic agent. The present invention also relates to kits suitable for use in such an asay.
Patent AU-1191500-A (AU)
Title: A processing circuit and a search processor circuit
Inventor: SVINGEN BAERGE
IPC: G06F17/30
Filed: 1999-11-12
Abstract: A non-numeric coprocessor for fuzzy information retrieval and pattern recognition has means for information processing and is connectable to a host computer and a data source. A plurality of internal processing elements are organized in a number of simultaneously operable window modules (W0, W1, . . . ) a arranged for inspecting data streams from said source. The processing elements compare data stream bytes with predetermined upper and lower bounds, to decide whether a byte is within said bounds, and, if so, to produce a hit signal. Each window module has a window match logic for correlating hit signals from its different processing elements, and to produce a window match signal, by the occurrence of a predefined match. By structuring the coprocessor in this manner, a parallel processing potential is attained, which can be utilized by data routing means (12) to allow for separate data streams to be routed to individual or chained window modules selectably configured as groups of windows or super-windows according to application needs.
Patent AU-1234402-A (AU)
Title: Establishment of biological cut-off values for predicting resistance to therapy
Inventor: HERTOGS KURT
IPC: G01N33/50
Filed: 2001-10-22
Abstract: The present invention concerns methods and systems for improving the accuracy of predicting resistance of a disease to a therapy. In one embodiment of the invention, mean and standard deviation (SD) values of fold change in normalized sensitivity, relative to a laboratory wild type standard pathogen or malignant cell are calculated to demonstrate that the patient samples display inherently different degrees of variation in susceptibility to each therapy. In another embodiment, the 2xSD value for each therapy is used as the cut-off between sensitive (within normal susceptible range) and resistant (above normal susceptible range).
Patent AU-1248692-A (AU)
Title: Pressure switch for use, in particular, in hand-held implements
IPC: H01H9/06
Filed: 1992-02-24
Abstract: In the invention disclosed, lateral pressure, particularly in the held section of a writing or similarly shaped implement, is transmitted by sliding elements (3) mounted on a rigid carrier (1), the sliding elements being at leastly partly surrounded by intermediate elements (4). The sliding elements (3) are pushed together in the non-operative position by spring-action means (5) or magnetic means. If external pressure is exerted on the intermediate elements (4), at least one sliding element (3) is displaced, and an adjustable signal receiver (6) is activated by means of a contact maker (9). In the embodiment shown in the figure, the mobile carrier (2) is moved forwards under the action of lateral pressure.
Patent AU-1297300-A (AU)
Title: A method for determining a mimotope sequence
Inventor: SLOOTSTRA JELLE WOUTER
IPC: C12Q1/68
Filed: 1999-11-15
Abstract: The invention relates to a method for determining a mimotope sequence for a receptor comprising the steps of: a) providing a library of test sequences; b) determining the activity of each test sequence of the library towards the receptor; c) identifying a test sequence comprising at a certain position a building block which, according to the results of step b) is favored at said position; d) providing a next library of test sequences, based on said test sequence identified in step c), by replacing a building block at selected positions of the identified test sequence with selected building blocks; e) determining the activity of each test sequence of the library provided in step d) towards the receptor; f) identifying a test sequence comprising at a certain position a building block which, according to the results of step e), is favored at said position; g) repeating steps d) - f) for the library of test sequences provided in step d), for a number of cycles sufficient for finding in step f) a mimotope sequence that gives sufficient activity towards the receptor.
Patent AU-1406900-A (AU)
Title: Flow regulator
Inventor: SHAY OFER
IPC: A61M5/168
Filed: 1999-11-29
Abstract: The invention relates to a variable flow regulator adopted to provide accurate flow rates at low flow and ultra low flow rates. The regulator comprises a wide-range flow regulator for low fluids flow, comprising a housing divided into a first and second chambers by means of an elastic diaphragm. The chamber is provided with a fluid inlet and an outlet connected to a labyrinth path.
Patent AU-1571688-A (AU)
Title: Novel proteolytic enzymes
Inventor: SAMAL BABRU B
IPC: C12N15/09
Filed: 1988-03-28
Abstract: This disclosure relates to a novel class of serine proteases isolated from a culture medium of fungus Tritirachium album. The serine proteases disclosed have a high degree of stability in detergent formulations. In addition, this disclosure relates to a process for producing such serine proteases using recombinant techniques.
Patent AU-1590599-A (AU)
Title: A method for directional stable transformation of eukaryotic cells
Inventor: GORDON-KAMM WILLIAM J
IPC: C12N15/31
Filed: 1998-11-17
Abstract: The invention provides DNA construct comprising in the 5' to 3' direction of transcription a promotor functional in a plant, an intron, a nucleotide sequence of interest, and a terminator region, said DNA construct comprising two non-identical recombination sites, where one of said non-identical recombination site is contained within said intron.
Patent AU-1648600-A (AU)
Title: Use of isatin derivatives as ion channel activating agents
Inventor: JENSEN BO SKAANING
IPC: A61P21/00
Filed: 1999-12-03
Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents. The SK/IK channel activating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK channels, in particular respiratory diseases such as asthma, cystic fibrosis, chronic obstructive pulmonary disease and rhinorrhea, convulsions, vascular spasms, coronary artery spasms, renal disorders, polycystic kidney disease, bladder spasms, urinary incontinence, bladder outflow obstruction, irritable bowel syndrome, gastrointestinal dysfunction, secretory diarrhea, ischaemia, cerebral ischaemia, ischaemic heart disease, angina pectoris, coronary heart disease, traumatic brain injury, psychosis, anxiety, depression, dementia, memory and attention deficits, Alzheimer's disease, dysmenorrhea, narcolepsy, Reynaud's disease, intermittent claudication, Sjorgren's syndrome, migraine, arrhythmia, hypertension, absence seizures, myotonic muscle dystrophia, xerostomi, diabetes type II, hyperinsulinemia, premature labor, baldness, cancer, and immune suppression.
Patent AU-1660292-A (AU)
Title: Valve control mechanism
IPC: F01L1/18
Filed: 1992-04-24
Abstract: PCT No. PCT/AU92/00187 Sec. 371 Date Jun. 2, 1994 Sec. 102(e) Date Jun. 2, 1994 PCT Filed Apr. 24, 1992 PCT Pub. No. WO92/19847 PCT Pub. Date Nov. 12, 1992A control mechanism (1) for an engine valve (29) comprising two rotatable cams (8, 10) which engage a lever (2) at two follower regions (23, 34) at different positions, the lever (2) having a zone of application (35) linked to the valve (29) whereby rocking movement of the lever (2) consequent on rotation of the cams (8, 10) causes opening and closing of the valve (29), wherein one of the two cams (8) is in constant engagement with the lever (2) and the other cam (10) is in periodic engagement with the lever (2), a gap (26) being provided between the other cam (10) and its respective follower region (23) when the other cam (10) is not in constant engagement with the lever (2), the width of the gap (26) affecting the duration of opening and closing of the valve (29) and its stroke length. Preferably, the zone of application (35) of the lever (2) is movable longitudinally along the lever (2) to thereby vary the stroke length of the valve (29).
Patent AU-1730992-A (AU)
Title: Stabilized solid dosage forms of choline metal carboxymethylcellulose salicylate compositions
IPC: A61K9/20
Filed: 1992-05-29
Abstract: The stability of compositions of choline salicylate-metal salicylate-carboxymethylcellulose is improved by the incorporation therein of microcrystalline cellulose. The microcrystalline cellulose is linked to the remainder of the composition by liquid bridges and is preferably present in an amount of about 2.5-25% by weight. The microcrystalline cellulose enhances the stability of the composition and thereby enhances solid dosage forms thereof such as tablets, capsules, suppositories and granules.
Patent AU-2009388-A (AU)
Title: Caustic-stable modified polycarboxylate
Inventor: BORSETH DONALD G
IPC: C08F22/02
Filed: 1988-07-27
Abstract: A surfactant-modified polymer characterized in that it comprises a polycarboxylate backbone and at least 0.5 percent by weight nonionic surfactant chemically associated therewith, the surfactant-modified polymer being formed by the polymerization of a reactant compound selected from carboxylic acids, polycarboxylic acids and mixtures thereof in an aqueous media in the presence of a nonionic surfactant is disclosed.
Patent AU-2057101-A (AU)
Title: Polymorphic crystalline forms of celecoxib
Inventor: FERRO LEONARD J
IPC: A61K31/415
Filed: 2000-12-01
Abstract: Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory compound of low water solubility in a therapeutically effective amount, wherein the compound is present in the form of solid particles, about 25% to 100% by weight of which are smaller than 1 micrometer. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders and have particular advantages where rapid onset of therapeutic effect is desired. The novel Form I and Form II crystalline forms of celecoxib are described. The crystalline forms have unique chemical and physical properties relative to other solid state forms of celecoxib and are characterized by their powder x-ray diffraction (PXRD) patterns, differential scanning calorimetric (DSC) thermograms, and other physical characterizations.
Patent AU-2116600-A (AU)
Title: Apparatus for preventing flood water from entering a building
Inventor: ROY DOYLE
IPC: E06B9/00
Filed: 2000-01-25
Abstract: Apparatus for preventing flood water entering a building through a wall opening has a first member for permanent attachment to the wall and second member detachably fixed to the first member. The first member has a frame having first fixing mechanism and two upright members for permanent fixing to the wall around the opening and a third member bowed away from the building and having a flat upper surface. The second member has a curved member with circumferential flanges and a second fixing mechanism engaging the first fixing mechanism. Two flanges extend outwardly from the curved member, and third flange is perpendicular to flanges and to the curved member. The flanges fit flat against the members of the frame through a gasket with the third flange extending horizontally on top of the third member forming a step.
Patent AU-2195695-A (AU)
Title: The combination of growth hormone and insulin-like growth factor, for treating congestive heart failure
Inventor: CLARK ROSS G
IPC: A61K45/00
Filed: 1995-03-30
Abstract: Methods of enhancing myocardial contractility and cardiac performance in a mammal with congestive heart failure are disclosed. In a first method a mammal with congestive heart failure is treated by administering to the mammal an effective amount of a combination of growth hormone (GH) and insulin-like growth factor (IGF-I). A second method comprises administering to the mammal an effective amount of a combination of GH and IGF-I in the presence of an ACE inhibitor. This method results in enhancement of myocardial contractility and cardiac performance above the level achieved with ACE inhibition alone. Preferably the mammal is a human.
Patent AU-2262599-A (AU)
Title: Game system, corresponding method and related devices
Inventor: STADELMANN ANTON NIKLAUS
IPC: G07F17/32
Filed: 1999-02-17
Abstract: Game system in which a plurality of participants transmit to at least one central play station (3) participant play data for taking part in at least one game (31, 32, 33) in special messages by means of mobile radio devices (2) through the mobile radio network (1). The central play station (3) carries out games according to predefined game rules and transmits central game data in special short messages through the mobile radio network (1) to the mobile radio devices (2) of the participants. The mobile radio devices (2) include a SIM card (21) for the game system, which has a memory, programmed means and a processor in order to show to a participant playing instructions and game results on a display (22) of a mobile radio device (2), and to convey the data to the central play station (3) by means of said special short messages, and to store a p repaid amount which can be used to pay for wagers and to which winnings can be booked.
Patent AU-2424597-A (AU)
Title: Methods for diagnosing and treating alzheimer's disease
Inventor: GILCHREST BARBARA A
IPC: A61K38/00
Filed: 1997-03-28
Abstract: Methods for evaluating the risk of an individual to develop Alzheimer's disease using cultured neural crest-derived melanocytes are described. Also described are methods of therapy for Alzheimer's disease using peptides that bind to the neurotrophin receptor (p75<NTR>) and competitively inhibit the binding of beta-amyloid to the p75<NTR>.
Patent AU-2506692-A (AU)
Title: Hollow polymer latex particles
Inventor: LEE DOLK
IPC: C08F285/00
Filed: 1992-08-19
Abstract: This invention relates to polymer particles that are acid-free in the swellable polymer core and to hollow polymer particles derived therefrom, and to a process for the production of these particles. The acid-free core advantageously decreases the polymer particle's affinity to water. Applicants have discovered that non-carboxylated latexes having a variety of Tg's will swell at temperatures higher than the Tg of the polymer. These latex particles are useful as opacifying plastic pigments for various coatings and particularly as gloss-enhancing plastic pigments for paper and paperboard coatings. Preparation of the hollow polymer particle comprises the use of (meth)acrylate ester monomers, vinyl esters of carboxylic acids or a mixture thereof which are hydrolyzable and swellable at higher temperatures in alkaline environments. The particles may be encapsulated with a hard shell.
Patent AU-2670999-A (AU)
Title: Composition for promoting adhesion between rubber and textiles
Inventor: LI SHULONG
IPC: B32B25/10
Filed: 1999-02-09
Abstract: A composition for the promotion of adhesion between a rubber formulation and a textile substrate is provided. The inventive composition comprises either a mixture of specific amine functional silanes and organo-functional silanes having reactive groups or groups with an affinity for rubber. The inventive method entails the use of the inventive composition or a silane compound having both an amine moiety and a reactive group having an affinity for rubber formulations, particularly an unsaturated carbon-carbon bond. The composition may be utilized to adhere any standard reinforcement-type textile, such as polyester or polyamide, to a standard rubber composition, such as SBR, NBR, or EPDM. A method for adhering textiles to rubber formulations is also provided involving a pre-dip, -spray, -coat, and the like, of the inventive composition on a reinforcement-type textile surface followed by the contacting of the rubber formulation. Optionally, and preferably, the process involves the extra utilization of resorcinol-formaldehyde latex as an effective bonding agent to improve the adhesion between the two layers. The resulting textile-reinforced rubber product may be utilized as an automobile fan or timing belt, an automobile tire component, and any other rubber article which requires long-lasting, durable textile reinforcement.
Patent AU-2717195-A (AU)
Title: Saline soluble inorganic fibres
Inventor: JUBB GARY ANTHONY
IPC: D06L1/00
Filed: 1995-07-25
Abstract: A use is disclosed comprising the repeated exposure to temperatures of 1000 DEG C or more of refractory insulation comprising saline soluble fibres having a shrinkage as specified of less than 3.5% when exposed to 1000 DEG C for 24 hours and having a shrinkage as specified of less than 3.5% when exposed to 800 DEG C for 24 hours, the saline soluble fibres comprising vitreous fibres comprising SiO2 and either one or both of CaO or MgO and having a composition comprising (in weight %):- <TABLE> and being essentially free of fluxing components such as alkali metal oxides and boron oxide. <IMAGE>
Patent AU-2771595-A (AU)
Title: Method for manufacturing one-piece tape tabs for use with disposable absorbent articles
Inventor: GOULAIT DAVID JOSEPH KENNETH
IPC: B31D1/00
Filed: 1995-06-09
Abstract: A method for the manufacture of one-piece tape tabs to be used with disposable absorbent articles. The first step is to provide a backing substrate upon which the pressure-sensitive adhesive of the tape tab can be applied. Once the backing is provided, the pressure-sensitive adhesive is applied to regions of one side of the backing substrate. The backing substrate is then slit in a direction parallel to the machine direction forming tape tab stock that is preferably fed directly to the taper unit of the absorbent article manufacturing line. The taper unit cuts the tape tab stock comprising the pressure-sensitive adhesive into individual tape tabs, each having a fixed end and releasable end. The fixed end of each tape tab is joined to the chassis of an absorbent article by means of mechanically bonding the fixed end to the absorbent article. The mechanical bonding not only joins the fixed end of the tape tab to the absorbent article, but also forms a region on the outwardly facing surface of the fixed end of the tape tab that acts as a release surface for the pressure-sensitive adhesive. In preferred embodiments, an area of the absorbent article adjacent to the fixed end of the tape tab is also subjected to mechanical bonding. The mechanical bonding forms a region on the surface of the absorbent article that acts a release surface for the pressure-sensitive adhesive disposed on the releasable end of each tape tab.
Patent AU-2861995-A (AU)
Title: Method for the production of composites using a polyolefin component exposed to surface oxyfluorination
Inventor: CARSTENS PIETER ANDRIES BLATT
IPC: C08J7/12
Filed: 1995-06-16
Abstract: The invention provides a method of producing a composite material. The method comprises subjecting a surface of a polyolefin component comprising a polyolefin material to surface activation thereof, followed by the step of adhesively securing together the polyolefin component and a substrate component. The substrate component is selected from cementitious components and metal components, and the securing takes place at the activated surface of the polyolefin component. The invention also extends to a composite material comprising a polyolefin component and a substrate component adhesively secured together. The substrate component is selected from cementitious components and metal components. The components are secured together at a surface of the polyolefin component which is activated.
Patent AU-3027697-A (AU)
Title: Pharmaceutical compositions containing cyclosporine and a carrier comprising at least an ester of alpha-glycerophosphoric acid
Inventor: SALINI ALBERTO
IPC: A61K38/00
Filed: 1997-05-20
Abstract: A description is given of new pharmaceutical compositions containing cyclosporine, combined with a carrier comprising at least a derivative of alpha-glycerophosphoric acid, such as alpha-glycerophosphorylcholine, alpha-glycerophosphorylserine, alpha-glycerophosphorylethanolamine and alpha-glycerophosphoryl-myo-inositol, which allow cyclosporine bioavailability to significantly increase.
Patent AU-3049497-A (AU)
Title: Aromatic amidine derivatives useful as selective thrombin inhibitors
Inventor: KOO BON AM
IPC: A61K31/4465
Filed: 1997-05-31
Abstract: The present invention relates to a novel thrombin inhibitor which is effective even when orally administered. More specifically, the present invention relates to an aromatic amidine derivative represented by formula (I) and the salts thereof, which show potent selective inhibitory activity for thrombin in which (a), R, R1, R2, R3, A, W, Y and n are defined as described in the specification.
Patent AU-3058100-A (AU)
Title: Substituted 1-(pieridin-4-yl)-3-(aryl) isothioureas their preparation and therapeutic application
Inventor: RIEU JEAN-PIERRE
IPC: A61K31/5415
Filed: 2000-01-21
Abstract: The invention concerns novel substituted N-benzo(thia/oxa)zines-2-yl-1-arylalkyloxyalkyl-4-piperidinamine, their preparation and their therapeutic use. The invention concerns compounds of formula (1) wherein: X represents an oxygen or sulphur atom; Y represents either an alkylene radical, branched or not and containing 2 to 6 carbon atoms or a CH2-CH(OH)-CH2- radical. R represents a hydrogen, an alkyl radical, branched or not and containing 1 to 7 carbon atoms; R1 to R6, identical or different, represent a hydrogen, a saturated or unsaturated alkyl, branched or not and containing 1 to 5 carbon atoms, a saturated or unsaturated alkyloxy, branched or not and containing 1 to 5 carbon atoms, a halogeno, nitro, hydroxy, acyl or acyloxy group comprising 2 to 3 carbon atoms, an alkylamino group containing 1 to 5 carbon atoms, a trifluoro methyl or trifluoro methoxyl group; n is an integer ranging from 1 to 6 inclusively, and their pure, enantiomers or their mixtures, the therapeutically acceptable mineral and organic salts of the compounds of formula (1) and their possible hydrates.