baber/WOPTO huggingface dataset:
Patent CA-3120196-A1 (CA)
Title: Inhibitors of arg1 and/or arg2
Inventor: BEATTY JOEL
IPC: A61K31/025
Filed: 2019-11-15
Abstract: Compounds that are inhibitors of at least one of ARG1 and ARG2, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by ARG1 and ARG2 are also described herein.
Patent CA-3120999-A1 (CA)
Title: Capsule formulations
Inventor: LELETI MANMOHAN REDDY
IPC: A61K31/445
Filed: 2019-11-27
Abstract: The present disclosure provides solid solution capsule formulations of Compound 1 and methods of making the same. Also provided herein are methods of treating individuals suffering from or susceptible to a disease or disorder involving pathologic activation of C5a receptors by administering an effective amount of one or more solid solution capsules comprising Compound 1. Further provided herein are singe unit dosage capsules comprising certain amounts of Compound 1, and kits comprising a solid solution capsule comprising Compound 1.
Patent CA-3125444-A1 (CA)
Title: Expansion system for improved handling and avoidance of damage and/or crushing of expandable slit sheet paper
Inventor: GOODRICH DAVID PAUL
IPC: B31D5/00
Filed: 2020-01-22
Abstract: In some illustrative embodiments of the present invention, a novel expandable slit paper expansion device design is provided that, among other things, avoid complications of prior systems and eliminates the crushing effect of the rollers. Among other things, the preferred embodiments provide a unique structure that provides a novel "S" shape path of the expandable slit sheet paper, such that the expandable slit sheet paper is tortuously weaved between at least two expansion rollers without being compressed there-between, in a manner that the expandable slit sheet paper follows along surfaces of the expansion rollers without pinching or compression that occurs in the background art.
Patent CA-3127810-A1 (CA)
Title: Systems and methods for controlling product inventory
Inventor: DEFRANCESCO NICOLAS
IPC: G06Q10/08
Filed: 2021-08-11
Abstract: A computer-implemented is disclosed. The method includes: receiving a selection of a product; determining that there is insufficient available inventory of the product at a pick-up location; in response to the determining: selecting, based on inventory tracking data for the product, a first inventory location having available inventory of the product; determining, based on the first inventory location, the at least one possible pick-up location, and inventory transfer data, an inventory transfer time from the first inventory location to the pick-up location; and determining an earliest time of availability of a first quantity of the product at the pick-up location based on the inventory transfer time, and transmitting, to a customer device, the earliest time of availability of the first quantity of the product at the pick-up location for presenting, by the customer device, as available inventory at the pick-up location for pick up after the earliest time of availability.
Patent CA-3127898-A1 (CA)
Inventor: GANGAIAH DHARANESH MAHIMAPURA
IPC: C12N15/74
Filed: 2020-02-04
Abstract: The present invention relates to efficient delivery of anti-infective activity, immunomodulatory factors, or growth-promoting biomolecules directly to the digestive tract of an animal via a live delivery platform. The live delivery platform can be a genetically modified microorganism. Delivery can be accomplished with a Lactobacillus sp which colonizes the gastrointestinal tract. The anti-infective activity can be a bacteriocidal or bacteriostatic peptide, an antibody or fragment thereof which specifically recognizes a pathogen, or a phage, or a lytic peptide from a phage which specifically targets a certain pathogen.
Patent CA-3129476-A1 (CA)
Inventor: BRUCKBAUER WILHELM
IPC: F24C15/20
Filed: 2020-01-16
Abstract: The invention relates to a cooktop system (1) comprising a support (4) for supporting items to be cooked (6), at least one heating unit (5) for heating the items to be cooked (6), arranged at the support (4), and an extractor device (3) for extracting cooking vapors downwards, a total width (B) of the cooktop system (1) being at most 600 mm.
Patent CA-3132268-A1 (CA)
Inventor: FUJIMURA NAOKI
IPC: H04B7/0413
Filed: 2019-05-01
Abstract: Provided is a user device comprising a reception unit which, from a base station, receives one or more signals containing transmission configuration notification information, and a control unit which, on the basis of the transmission configuration notification information, determines whether or not an assumption of a QCL (Quasi-Co-Location) relationship between a first signal and a second signal is valid, wherein the control unit executes, for the first signal, an action based on the result of the determination.
Patent CA-3132512-A1 (CA)
Title: Hall effect prism sensor
Inventor: ANDERSON JOHN DOUGLAS
IPC: H01L43/14
Filed: 2020-03-21
Abstract: A physically unclonable function is an object that has characteristics that make it extremely difficult or impossible to copy. An array of randomly dispersed hard (magnetized) and soft (non-magnetized) magnetic particles that may be conducting or nonconducting that are disbursed in a binder create a particular magnetic field or capacitive pattern on the surface. This surface magnetic field and capacitive variations can be considered to be a unique pattern similar to fingerprint. The Hall effect prism is a sensor that measures the effects of these patterns by sensing the deformation of currents or electric potential flowing within or around a resistive substrate material that exhibits a substantial Hall effect coefficient.
Patent CA-3132992-A1 (CA)
Title: Microtreillis inverses transparents ou semi-transparents de polyacrylamide utilises en tant qu'agent de reduction de derive d'emulsion d'huile
Inventor: SEXTON FRANKLIN E
IPC: A01N25/04
Filed: 2020-03-13
Abstract: La présente invention concerne des compositions comprenant des microémulsions de polyacrylamide, par exemple des microtreillis inverses transparents ou semi-transparents de polyacrylamide, ainsi que des procédés et des formulations utilisant les compositions pour la gestion de ravageurs des cultures.
Patent CA-3134618-A1 (CA)
Title: Appareil de regeneration thermique
Inventor: STEINER THOMAS WALTER
IPC: F02G1/057
Filed: 2020-02-18
Abstract: L'invention concerne un appareil de régénération thermique comprenant un milieu de régénération comportant une pluralité de passages d'écoulement s'étendant entre des premier et second orifices, les passages d'écoulement facilitant l'écoulement du fluide dans un sens généralement transversal entre les premier et second orifices tandis que le milieu reçoit alternativement de l'énergie thermique du fluide et lui fournit de l'énergie thermique. Le milieu régénérateur comprend une pluralité de feuilles superposées, chaque feuille comportant une pluralité de canaux s'étendant à travers la feuille, les canaux ayant des parois latérales biseautées. Les canaux ont une largeur et un espacement dans la direction transversale et les canaux de chaque feuille adjacente superposée sont décalés transversalement de sorte que chaque canal s'étend entre et est en communication fluide avec une paire de canaux dans les feuilles adjacentes et les parois latérales biseautées des canaux redirigent l'écoulement du fluide entre les canaux des feuilles adjacentes pour former les passages d'écoulement. Les canaux sont allongés le long de la feuille dans une direction longitudinale orthogonale à la direction transversale et sont divisés par des ponts de feuille s'étendant transversalement, les ponts de feuille étant dimensionnés pour réduire la conduction thermique à travers le milieu dans la direction transversale.
Patent CA-3134964-A1 (CA)
Title: Modification d'un anticorps destine a une liaison de cd47 selective vis-a-vis de tumeurs
Inventor: HADJIVASSILIOU HARALAMBOS
IPC: C07K16/28
Filed: 2020-04-03
Abstract: L'invention concerne des anticorps qui comprennent au moins une partie Fab qui se lie à CD47 et au moins une partie Fab qui se lie à l'antigène associé à une tumeur (TAA) CD20. La partie Fab qui se lie à CD47 présente une faible affinité vis-à-vis de CD47. La partie Fab qui se lie à CD20 présente une affinité élevée vis-à-vis de CD20. L'anticorps se lie sélectivement à CD47 et bloque l'interaction avec CD47 avec SIRPa dans des cellules tumorales tout en étant dépourvu de liaison conséquente à CD47 dans des cellules normales.
Patent CA-3135383-A1 (CA)
Inventor: GERKEN PHILIP A
IPC: A61P29/00
Filed: 2020-04-23
Abstract: The invention provides compounds of formula (I): (I) or pharmaceutically-acceptable salts thereof, that are inhibitors of Janus kinases and release an active metabolite in vivo. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat inflammatory skin diseases and other diseases.
Patent CA-3137423-A1 (CA)
Title: Ergo work station
Inventor: JANSEN MONICA HENRICA JOHANNA
IPC: A47B77/02
Filed: 2019-04-08
Abstract: A workstation including a frame panel having a first inset and cap beams. An inner skirt is connected at least partially around the frame panel, and has a stepwell portion including a kickplate. A first mount plate is connected to the kickplate and extends inwardly. An outer skirt is disposed at least partially around the inner skirt. The outer skirt is slidable with respect to the inner skirt. A first mounting brace is connected to at least two of the cap beams. A second mount plate is connected to the first mounting brace and disposed inwardly. A first actuator is disposed between the first mount plate and the second mount plate, and through the first inset. The first actuator is configured to change in length and hence to change a distance between the first mount plate and the second mount plate. A work surface is connected to the outer skirt.
Patent CA-3138237-A1 (CA)
Title: Klebsiella vaccine and methods of use
Inventor: BICALHO RODRIGO
IPC: C12P21/02
Filed: 2020-04-27
Abstract: Provided are compositions and methods that include a K. pneumoniae yidR protein or an antigenic segment of the protein, and homologous of the protein, and antigenic segments of the homologs. The compositions can be provided as vaccine formulations for use with humans and non-human animals, including but not limited to dairy cows. The compositions and methods are useful for prophylaxis and/or therapy of conditions associated with Gram negative bacteria that include K. pneumonia, E. coli, and other pathogenic Gram negative bacteria. The conditions include such bacterial infections generally, and include specifically mastitis and metritis. The compositions and methods can also improve fertility and milk production. Administration of the compositions can improve the likelihood of a first service conception.
Patent CA-3138873-A1 (CA)
Inventor: CLAGG KYLE BRADLEY PASCUAL
IPC: C07D487/04
Filed: 2020-05-07
Abstract: L'invention concerne un procédé de synthèse, comprenant une étape de fabrication d'un composé imidazo-pyrimidine par couplage d'un premier composé de formule (II) avec un second composé de formule (III) suivi d'une étape de déprotection et de tosylation. Les procédés sont capables de produire une molécule substituée par un isotope ayant une pureté supérieure à 95 % par rapport à des molécules non substituées par des isotopes. L'invention comprend en outre des composés de formule :
Patent CA-3139595-A1 (CA)
Title: Water out alarm
Inventor: BARKER DEAN
IPC: A61M16/10
Filed: 2011-04-26
Abstract: The present invention provides for an irnproved method of determining a water out condition in a humidified gases supply apparatus. The method includes a two step process including a primary determination of a water out condition and a secondary determination of a water out condition. This primary determination is made during observation of the normal operation of the apparatus. During the secondary determination the method takes temporary control over the humidifying part of the apparatus. The secondary determination confirms or contradicts the primary determination.
Patent CA-3140076-A1 (CA)
Inventor: JADHAV PRAMODKUMAR DINKAR
IPC: A61K36/185
Filed: 2020-05-13
Abstract: L'invention concerne des procédés d'extraction d'un ou de plusieurs composés chimiques à partir d'un matériau végétal de cannabis. Selon certains modes de réalisation, le procédé peut comprendre les étapes consistant à : fournir le matériau végétal de cannabis ; extraire le matériau végétal de cannabis avec un solvant pour produire un extrait au solvant ; et filtrer l'extrait au solvant à travers un matériau filtrant pour produire un extrait filtré. L'invention concerne en outre des systèmes associés. L'invention concerne également des extraits de cannabis associés et des produits associés comprenant des extraits de cannabis.
Patent CA-3141625-A1 (CA)
Title: Band-shaped machining tool having buffer particles
Inventor: KULLMANN JORG H
IPC: B28D1/12
Filed: 2020-06-18
Abstract: The invention relates to a machining tool (1) comprising a strip-shaped teeth support body (2) and a plurality of teeth (3) each having a tooth tip (4) which is coated with cutting particles (5) to form a plurality of geometrically undefined cutting edges. The tooth tip (4) is furthermore coated with buffer particles (6) made of a different material than the cutting particles (5). The buffer particles (6) are located between the cutting particles (5).
Patent CA-3141637-A1 (CA)
Title: Methods and apparatus for startup processes for a power machine
Inventor: BREUER JIM
IPC: B60R16/02
Filed: 2020-06-29
Abstract: A power machine (200) can be configured to operate in one or more startup modes during startup processes (300), including during startup processes (310) for displays (286) or other input devices. Access to power machine functionality, including access only to limited power machine functionality, can be enabled during the startup processes (300) according to permissions (332) of the startup mode.
Patent CA-3143376-A1 (CA)
Title: Plant and method for liquefying gas
Inventor: BARJHOUX PIERRE
IPC: F25J1/02
Filed: 2020-06-08
Abstract: Plant and method for liquefying a flow of gas, comprising a cooling circuit (2) which is provided with an upstream end which is intended to be connected to a source (3) of pressurised gas to be liquified and a downstream end (4) which is intended to be connected to a user member, the plant (1) comprising, between the upstream and downstream ends (4), a set of members (5, 6) which are intended to liquefy the gas and comprise at least one exchanger (5) for cooling the gas, and at least one expansion turbine (6) which is mounted on a rotary axle which is supported by at least one bearing (7) of the gas-static type, the cooling circuit (2) comprising a pressurised gas injection conduit (8) having an upstream end which is intended to receive pressurised gas supplied by the source and a downstream end which is connected to the bearing (7) in order to provide support to the rotary axle, the plant (1) comprising a conduit (9) for recovering the gas which has been used in the bearing (7), the conduit (9) for recovering the gas comprising an upstream end which is connected to the bearing (7) and a downstream end, characterised in that the downstream end of the conduit (9) for recovering the gas is connected to the cooling circuit (2) between the upstream and downstream ends thereof in order to recycle at that location at least a portion of the gas which has been used to support the rotary axle of the bearing (7) with a view to liquefying said gas.
Patent CA-3143566-A1 (CA)
Title: Systems and methods for providing a graphical user interface for intraocular lens implantation planning
Inventor: THOE DAVID
IPC: A61B3/00
Filed: 2020-09-19
Abstract: Systems and methods are presented for providing a graphical user interface (GUI) for assisting eye-care professionals in intraocular lens implantation planning in a two-stage process. During the first stage, first biometric data of a patient's eye is obtained. A first set of lens products comprising a first lens product is determined based on the first biometric data. A first grid is provided via the GUI to present the first set of lens products. During the second stage, second biometric data of the eye is obtained after an existing lens of the patient's eye is removed. A second set of lens products comprising a second lens product is determined based on the second biometric data. A second grid is provided via the GUI to present the second set of lens products and a difference between the first and second lens products.
Patent CA-3144047-A1 (CA)
Title: Improvements relating to toilet modules
Inventor: THOMSON STEPHEN JOHN
IPC: E03D11/12
Filed: 2020-07-24
Abstract: Toilets having a water trap and a flushable bowl are considered more hygienic than squat toilets. However, squat toilets can be better at assisting healthy bowel function. The present invention provides a toilet module having a toilet bowl and which also has a toilet bowl support mechanism. The toilet bowel support mechanism allows the toilet bowl to be moved to a position in which the person using the toilet to adopt more of a squatting posture when cleansing their bowels. The toilet bowl support mechanism is configured to move the toilet bowl to and between a first position and a second position, the first position is characterised in that the front end of the toilet bowl is lower than the aft end of the toilet bowl, and the second position is characterised in that the front end of the toilet bowl is above the aft end of the toilet bowl. The first position makes it easier for folk with limited mobility to sit on the toilet, and the second position allows the seated person to adopt a squatting posture.
Patent CA-3147446-A1 (CA)
Title: Conductivity control systems
Inventor: REBACZ NATALIE
IPC: A61M1/16
Filed: 2020-08-03
Abstract: A dialysis system has a module with a dialyzer configured to remove one or more substances from a dialysis solution as it passes through a dialyzer. The module has a fluid line, a sorbent cartridge, and a sodium control system adapted to actively alter a sodium concentration of dialysis solution passing through the fluid line as the dialysis solution exits the sorbent cartridge. The sodium control system has a conductivity sensor that sends a signal indicating the conductivity of the dialysis solution as the dialysis solution exits the sorbent cartridge, the conductivity meter being in communication with the sodium control system, a processor configured to receive the signal from the conductivity sensor, compare the conductivity signal to a threshold value lower than a prescription value, and cause the sodium control system to stop actively altering the sodium concentration if the signal is greater than the threshold value.
Patent CA-3151767-A1 (CA)
Inventor: ABINAVAM SRINATH S
IPC: G06Q20/32
Filed: 2020-09-25
Abstract: A cross-platform integration component is configured for operation on a plurality of different types of partner computing devices and/or platforms. The integration component provides a same interface on each different type of computing device. The integration component comprises a plurality of implementation modules, each configured to implement reader-based transactions on a respective type of computing device and/or platform. The integration component may further comprise a platform-independent component capable of implementing non-reader-based transactions across the plurality of platforms.
Patent CA-3152698-A1 (CA)
Inventor: BLAIR EAMONN MARTIN
IPC: C09K21/00
Filed: 2020-09-30
Abstract: L'invention concerne un matériau ignifugeant qui comprend un matériau nanoporeux déconstruit comprenant une pluralité d'éléments, et des matières solides d'une solution ignifugeante à l'intérieur des éléments du matériau nanoporeux. Elle concerne également un procédé de formation d'un matériau ignifugeant, consistant à combiner un matériau nanoporeux et une solution ignifugeante de telle sorte que les éléments du matériau nanoporeux absorbent la solution ignifugeante, et à évaporer le liquide à partir des éléments du matériau nanoporeux qui ont adsorbé la solution ignifugeante de façon qu'un concentré ou des matières solides de cette dernière restent à l'intérieur des éléments du matériau nanoporeux.
Patent CA-3157173-A1 (CA)
Title: Modulateurs atf6 et leurs utilisations
Inventor: PUJALA BRAHMAM
IPC: A61P25/28
Filed: 2020-10-09
Abstract: L'invention concerne des composés (1-2) utilisés en tant que modulateurs du facteur de transcription d'activation 6 (ATF6). Les composés peuvent être utilisés en tant qu'agents thérapeutiques pour le traitement de maladies ou de troubles médiés par ATF6 et peuvent trouver une utilisation particulière dans le traitement d'infections virales, de maladies neurodégénératives, de maladies vasculaires ou du cancer. (Formule (1-2))
Patent CA-3157192-A1 (CA)
Title: Compositions and methods for pulmonary surfactant-biomimetic nanoparticles
Inventor: Wu Mei Xiong
IPC: A61K9/48
Filed: 2020-10-06
Abstract: Compositions and methods comprising Pulmonary Surfactant (PS)-biomimetic nanoparticles are disclosed. Specifically, the disclosure is related to a composition comprising a nanoparticle with an average size of 200-400 nm, including a plurality of pulmonary surfactant biomimetic molecules, wherein the nanoparticle is negatively charged; and one or more cargo molecules that are enveloped by the nanoparticle, wherein the cargo molecule has a molecular weight up to 1200 Da.
Patent CA-3157292-A1 (CA)
Inventor: HEATH ANTHONY
IPC: F41G1/033
Filed: 2020-11-16
Abstract: L'invention concerne des procédés et des systèmes destinés à un ensemble viseur d'arme modulaire. Un viseur d'arme peut comprendre une base, un banc optique, un ensemble de réglage et/ou un boîtier. La base peut être conçue pour être fixée amovible à une arme. Le banc optique peut comprendre une pluralité d'éléments optiques fixés à un support de composant unitaire. Une position relative de la pluralité d'éléments optiques peut délimiter un trajet optique du viseur d'arme. La base, le banc optique, l'ensemble de réglage et le boîtier peuvent être conçus sous la forme de modules séparés. Par exemple, le trajet optique du banc optique peut rester constant pendant le réglage et/ou le remplacement de la base, de l'ensemble de réglage et/ou du boîtier. Un changement de position de la base, de l'ensemble de réglage et/ou du boîtier ne peut pas modifier la position relative de la pluralité d'éléments optiques les uns par rapport aux autres.
Patent CA-3164850-A1 (CA)
Inventor: EVERY JOSEPH J
IPC: E02F3/60
Filed: 2021-01-20
Abstract: L'invention concerne un système de retenue destiné à une ligne sur une bobine. Le système de retenue peut comprendre un composant de base qui comprend un élément de réception de retenue à l'intérieur d'une surface côté ligne du composant de base. Le système de retenue peut comprendre un composant de mise en prise de ligne qui comprend une surface de mise en prise, la surface de mise en prise comprenant une partie qui est perpendiculaire au composant de base pour venir en prise avec une ligne, la surface de mise en prise étant en butée contre la surface côté ligne. Le système de retenue peut comprendre un élément de retenue amovible qui est configuré pour retenir la ligne entre la surface de mise en prise et le composant de retenue amovible lorsque ce dernier est installé à l'intérieur de l'élément de réception de retenue.