baber/WOPTO huggingface dataset:
Patent CA-2847143-A1 (CA)
Inventor: FOSTER KEITH ALAN
IPC: A61K36/06
Filed: 2000-09-25
Abstract: A method of treatment of disease by inhibition of cellular secretory processes is provided. The method has particular application in the treatment of diseases dependent upon the exocytotic activity of endocrine cells, exocrine cells, inflammatory cells, cells of the immune system, cells of the cardiovascular system, and bone cells. Agents and compositions therefor, as well as methods for manufacturing these agents and compositions, are provided. In a preferred embodiment a clostridial neurotoxin, substantially devoid of holotoxin binding affmity for neuronal cells of the presynaptic muscular junction, is associated with a targeting moiety. The targeting moiety is selected such that the clostridial toxin conjugate so formed may be directed to a non-neuronal target cell to which the conjugate may bind. Following binding, a neurotoxin component of the conjugate, which is capable of inhibition of cellular secretion, passes into the cytosol of the target cell by cellular internalisation mechanisms. Thereafter, inhibition of secretion from the target cell is effected.
Patent CA-2848023-A1 (CA)
Title: Methods for tagging dna-encoded libraries
Inventor: KEEFE ANTHONY D
IPC: C40B50/06
Filed: 2012-09-07
Abstract: The present invention relates to oligonucleotide-encoded libraries and methods of tagging such libraries. In particular, the methods and oligonucleotides can include one or more 2 '-substituted nucleotides, such as 2'-O-methyl or 2'-fluoro nucleotides, and other conditions or reagents to enhance enzyme ligation or one or more chemical functionalities to support chemical ligation.
Patent CA-2849505-A1 (CA)
Inventor: DHALLA ARVINDER
IPC: A61K31/495
Filed: 2012-09-20
Abstract: It is discovered that sodium-channel blockers inhibit the secretion of glucagon from pancreatic alpha cells. The present disclosure, based on such discoveries, provides compositions and methods for the treatment of hyperglycemia and related diseases and conditions with Na-channel blockers.
Patent CA-2851000-A1 (CA)
Title: Subfloor component and method for manufacturing same
Inventor: AMEND VICTOR
IPC: E04F15/024
Filed: 2014-05-02
Abstract: A subfloor component comprises an insulating foam panel having first and second opposing faces and a plurality of intersecting grooves in the first face to define, in cross-section, a plurality of pedestals having at least one wall extending toward the second face, a moisture-resistant layer formed on the first face of the panel that conforms to the pedestals, and a hardboard layer on the second face of the panel.
Patent CA-2851517-A1 (CA)
Inventor: MARTIN BRIAN
IPC: H04W4/08
Filed: 2010-06-16
Abstract: A method comprises detecting a local network access node; generating a measurement report based on the detected local network access node; and in response to determining that a closed subscriber group proximity indication for the detected local network access node has not been sent to a serving network access node, including a closed subscriber group proximity indication in the generated measurement report.
Patent CA-2852154-A1 (CA)
Title: A medical implant, a kit and a method of manufacturing a 3d fabric of strands for forming a medical implant
Inventor: HEIPL MICHEAL
IPC: D04C3/48
Filed: 2012-10-26
Abstract: The disclosure relates to a method of manufacturing a medical implant or structures for a medical implant. Disclosed is an improved occluder (1), which does not damage the surrounding body tissue. In one embodiment, a method of manufacturing a 3D fabric of strands for forming an occluder is provided. The method comprises intertwining the strands along a length of the 3D fabric for forming a primary 3D fabric structure. The intertwining is non-continuous, i.e. the braiding procedure can be halted, for forming a secondary structure of the 3D fabric without intertwining.
Patent CA-2852859-A1 (CA)
Inventor: CARICCIA GIANLUCA
IPC: F16F15/139
Filed: 2012-10-22
Abstract: The dual mass flywheel comprises a spring assembly (4; 104; 112; 128; 129), if necessary, with two stages of which one can include a spiral spring. Furthermore, the dual mass flywheel comprises a friction damping system (111) that applies torque independently of the rotational speed of the flywheel.
Patent CA-2852972-A1 (CA)
Title: Polycrystalline diamond compact with increased impact resistance
Inventor: PETREE RUSTY
IPC: C01B31/06
Filed: 2013-12-06
Abstract: A polycrystalline diamond (PCD) with diamond grains includes a first zone of the diamond grains and a second zone of the diamond grains. The first zone forms a working surface and a first catalyzing material is disposed within voids of the diamond grains in the first zone. A second catalyzing material is bonded to the diamond grains disposed in the second zone. The first catalyzing material in the first zone is connected to the diamond grains disposed in the first zone less intimately than the second catalyzing material is bonded to the diamond grains in the second zone.
Patent CA-2854347-A1 (CA)
Title: Commercial game system and method
Inventor: WILEN RICHARD
IPC: G06Q30/02
Filed: 2014-06-16
Abstract: A system and method for providing a commercial game that poses questions to a user related to advertisements that the user views or listens to using a multimedia device such as a computer connected to the Internet. Points may be awarded to the user based on the number of questions answered correctly, the number of advertisements viewed, the length of time advertisements are viewed, the number of attempts at answering each question before providing the correct answer, or other advertiser-selected criteria. Points earned by the user are immediately redeemable for services such as subscription services, movies downloads, Pay-Per-View credits, or for any other tangible or intangible good, service, or reward representing a monetary value. If the user provides an incorrect answer to a question, the user is permitted to watch the advertisement multiple times until a correct answer is provided and points are awarded.
Patent CA-2855878-A1 (CA)
Title: Buse rotative haute pression autoregulee a palier fluide avec equilibrage de poussee
Inventor: WRIGHT DOUGLAS E
IPC: B05B15/68
Filed: 2009-12-23
Abstract: Buse rotative haute pression dotée d'un arbre tournant (1) fonctionnant à l'intérieur d'un boîtier fixe (B, C), où l'effort axial qui agit sur l'arbre en raison de la pression du fluide à l'entrée de l'arbre est équilibré en permettant le passage d'une petite quantité de fluide sous pression soutirée en direction d'une chambre tronconique, entre l'extérieur de l'arbre et l'intérieur du boîtier, où la pression du fluide peut agir axialement sur l'arbre dans un sens opposé de manière à équilibrer l'effort axial d'entrée. L'équilibre des efforts axiaux est autorégulé par la commande de l'échappement du fluide à travers une région tronconique, entre l'arbre et le boîtier. De plus, cela crée un palier fluide entre les deux surfaces et permet l'utilisation de têtes tournantes interchangeables (15) d'éjection dotées d'orifices (16) d'éjection qui peuvent être orientées pratiquement selon n'importe quelle configuration souhaitable, notamment axialement vers l'avant de la buse.
Patent CA-2857446-A1 (CA)
Inventor: BILODEAU YAN
IPC: B44C3/00
Filed: 2014-07-18
Abstract: Disclosed is a method of producing a pattern for a decorative panel. The method includes applying a clear gel coat on a mold to form a clear layer. The clear layer is cured and then digitally printed with one or more inks so as to produce a pattern on the clear layer. Also disclosed is a decorative panel including a clear layer, an opaque layer and a pattern digitally printed on the clear layer, between the clear and opaque layers, such that the pattern is visible through the clear layer.
Patent CA-2857459-A1 (CA)
Inventor: OJEDA CARLOS
IPC: F04D29/40
Filed: 2012-11-28
Abstract: A bladeless fan assembly is provided which includes a housing having an air inlet and an air outlet. A blower is located within the housing, and includes a motor for driving an air stream between the air inlet and air outlet of the housing. A directional scoop is affixed to the housing at the air outlet. The directional scoop including a first end, connected to the housing at the air inlet, and a second open end opposite the first end. The first end and second open end of the directional scoop define a longitudinal length "L" of the directional scoop having a longitudinal axis "X." The directional scoop is arcuate is shape, being curved along the longitudinal axis between the first and the second open end, and about the longitudinal axis to define an open channel along the length of the directional scoop.
Patent CA-2858221-A1 (CA)
Title: Novel complexes of water-soluble polymers, and uses thereof
Inventor: HUND RENE
IPC: C08L33/24
Filed: 2014-07-30
Abstract: Polymer complex obtained by polymerization of water-soluble monomers: in the presence of a host polymer comprising vinylamine functions and of a non-polymeric transfer agent, and in the absence of branching or crosslinking agent of ethylenic polyfunctional type.
Patent CA-2859360-A1 (CA)
Inventor: WIESNER JOEL D
IPC: H04W4/90
Filed: 2012-12-11
Abstract: Wireless relay modules for enabling alarm recognition and alerts in networked communications between a series of medical devices and a remote monitoring device via wireless relay networks and/or internet-accessible wireless communications networks. The wireless relay module including a receiver, a first transmitter coupled to the wireless relay network, a second transmitter coupled to the internet-accessible wireless communication network, a controller and a display. The controller identifying if received medical device data from the medical device includes an alarm condition and causing the display to display an alert accordingly. The wireless relay module may additionally include a speaker alone or in combination with a microphone for providing an audible alert of the alarm condition and verbal communication between a local healthcare provider and a clinician at the remote monitoring device.
Patent CA-2860968-A1 (CA)
Inventor: ITAKURA HIROSHIGE
IPC: A23L1/30
Filed: 2013-01-10
Abstract: A serum resistin level reducing agent which comprises a disrupted product of a cell wall of Chlorella pyrenoidosa, can be used for reducing a serum resistin level, and is an agent for oral administration. A food or beverage composition for reducing a serum resistin level, which contains a disrupted product of a cell wall of Chlorella pyrenoidosa and can be used for reducing a serum resistin level. A method for reducing a serum resistin level by applying/administering a disrupted product of a cell wall of Chlorella pyrenoidosa through an oral route. Use of a disrupted product of a cell wall of Chlorella pyrenoidosa by the administration through an oral route for the purpose of reducing a serum resistin level.
Patent CA-2862288-A1 (CA)
Title: Procede de preparation de silices precipitees
Inventor: ALLAIN EMMANUELLE
IPC: C01B33/193
Filed: 2013-01-23
Abstract: L'invention concerne un procédé de préparation de silices précipitées dans lequel : (i) on forme un pied de cuve ayant une concentration en silicate de métal alcalin M inférieure à 20 g/L, (ii) on y ajoute de l'acide, jusqu'à ce qu'au moins 50 % de la quantité de M20 soient neutralisés, (ii) on ajoute, simultanément, du silicate et de l'acide, de telle manière que le taux de consolidation soit supérieur à 4 et d'au plus 100, (iv) on ajoute de l'acide jusqu'à un pH de 2,5 à 5,5, dans lequel l'acide utilisé dans au moins une de ses étapes est un acide concentré de préférence choisi dans le groupe formé par l'acide sulfurique présentant une concentration d'au moins 80% en masse, en particulier d'au moins 90% en masse, l'acide acétique ou l'acide formique présentant une concentration d'au moins 90% en masse, 1' acide nitrique présentant une concentration d'au moins 60% en masse, 1' acide phosphorque présentant une concentration d'au moins 75% en masse, 1' acide chlorhydtique présentant une concentration d'au moins 30% en masse.
Patent CA-2862492-A1 (CA)
Inventor: BLAKEMORE STEPHEN J
IPC: A61P35/00
Filed: 2013-01-23
Abstract: L'invention concerne une méthode de traitement du cancer au moyen d'un inhibiteur du protéasome. L'invention concerne également une méthode de traitement d'un patient souffrant d'un cancer basée sur des niveaux élevés d'expression de NF?B, tels que mesurés par un score H de l'échantillon tumoral du patient au moyen d'un dosage NF?B p65. L'invention concerne en outre une méthode pour déterminer si un patient doit être traité avec un inhibiteur du protéasome basée sur le niveau de NF?B p65 dans l'échantillon tumoral du patient.
Patent CA-2862991-A1 (CA)
Title: Frequency capping of addressable content
Inventor: HABERMAN SETH
IPC: H04N21/2668
Filed: 2013-01-10
Abstract: Systems and methods for frequency capping of content are described herein. For example, frequency cap information may be configured to indicate a content exposure limit for a content presentation. The number of exposures to the content presentation at a particular household may be monitored. If the number of exposures is equal to or greater than the content exposure limit, the content may be prevented from being presented to the household. The frequency cap information may be used alone or in combination with other information, such as household demographic, timeframe, and day-part information.
Patent CA-2864316-A1 (CA)
Title: Centralized call processing
Inventor: RAE ROBERT L
IPC: G06Q30/00
Filed: 2007-04-10
Abstract: Disclosed are systems and methods which provide a centralized architecture for call processing. Embodiments utilize voice over Internet protocols (VoIP) to carry calls from a location at which calling services are provided to a centralized call processing platform providing call processing functionality, such as calling party identification, call validation, call routing, and connection to the public switched telephone network (PSTN).  Call processing gateways may be utilized to provide plain old telephone service (POTS) analog line interfaces for use with a plurality of telephone sets disposed for use at a location and at least one wide area network (WAN) interface for providing high speed data communication to a centralized call processing platform. PSTN interfacing by a call processing platform may be provided as a VoIP connection to the PSTN and/or as POTS trunking. Call processing platforms may provide for data sharing, aggregation, and/or analysis across multiple facilities served.
Patent CA-2864469-A1 (CA)
Inventor: REED ROBERT A
IPC: A61K47/04
Filed: 2013-02-15
Abstract: The present invention relates to a formulation of thertnosensiiive liposomes, and more specifically to a formulation of liposomes comprising phospholipids and a surface active agent, wherein the liposomes support long term storage at temperatures less than or equal to about 8 °C, control degradate formation to maximize product potency and release their contents at mild hyperthermic temperatures. Methods of making formulations are also described.
Patent CA-2866568-A1 (CA)
Inventor: FINNSSON THORIR
IPC: A22C17/00
Filed: 2013-03-08
Abstract: This invention relates to a cutting apparatus (100) for cutting food items (201) conveyed on a conveyor (101) including at least one conveyor belt (102). A cutter (103) is arranged above a gap (104) extending across the at least one conveyor belt. The cutter is positioned in relation to the gap such that the cutting path of the cutter extends through the food items and the gap and below the surface level of the at least one conveyor belt. The cutter is adapted to be connected to a control mechanism for operating crosswise movement of the cutter along the gap. The gap is formed between adjacent elongated supporting means (202, 203) such as rollers with a fixed internal arrangement, where the adjacent elongated supporting means and the cutter is adapted to be connected to a control mechanism for operating back and forth movement of the adjacent elongated supporting means and the cutter parallel to the conveying direction (205) while maintaining the internal arrangement of the adjacent elongated supporting means and the cutter fixed.
Patent CA-2867327-A1 (CA)
Inventor: MARLAND CHRISTOPHER N
IPC: G06Q10/06
Filed: 2012-04-25
Abstract: Various systems and methods are disclosed for making and using an anonymized database for an industrial enterprise, such as oilfield operations. Providing statistical performance indicators for groupings of an activity in the oilfield allow for the information in confidential data sets to be shared without compromising the confidentiality of any one data entry. Comparisons may be made between or among oilfields with differing technologies, differing rig configurations, or even different crews when sufficient data are available.
Patent CA-2869175-A1 (CA)
Title: Rotary-leaf/-casement drive
Inventor: BISANG HANS RUDOLF
IPC: E05F15/10
Filed: 2013-04-05
Abstract: The present invention relates to a rotary drive for at least one leaf/casement, in particular a door leaf or a window casement, comprising: at least one output shaft (330) for coupling to the at least one leaf/casement; at least one motor (20), which acts on the output shaft (330) via at least one downstream gear mechanism (30); an energy-store module (112), which has a linear line of action and uses transmission elements (14, 32, 326) to subject the circumference of an eccentric cam disc (331), arranged in a rotationally fixed manner on the output shaft (330), to pressure; and an intermediate shaft (320), which is offset in relation to the line of action of the energy-store module (112) and is provided between the motor (20) and output shaft (330). The rotary drive is characterized in that the transmission elements (14, 32, 326) comprise a roller lever (32), which is mounted in a rotatable manner on the intermediate shaft (320) and has a cam-follower roller (326) spaced apart from the intermediate shaft (320), wherein the cam-follower roller (326), pressed circumferentially against the eccentric cam disc (331), interacts with the output shaft (330), and the energy-store module (112) is arranged on the motor side in relation to the intermediate shaft (320). The present invention also relates to a clamping piece for connection to the output shaft (330), wherein the clamping piece has a lateral lever which interacts with an eccentrically mounted and steplessly adjustable stop element.
Patent CA-2873181-A1 (CA)
Inventor: CORNELIUS CHARLES C
IPC: F16C33/58
Filed: 2012-05-17
Abstract: A high load capacity bearing that includes a cylindrical outer sleeve that fits around a separable cylindrical outer race assembly. The outer race assembly includes a set of non-helical grooves formed on its inside surface that mesh and engage teeth formed on the outside surface of a plurality of rotating rollers that are longitudinally and axially aligned inside the outer race assembly. The rollers are longitudinally aligned and evenly space apart and rotated as a unit inside the outer race assembly. Located inside the rollers is an inner race with non-helical grooves formed on its outside surface that mesh and engage the teeth on the rollers. The inner race includes a smooth inside bore that fits around the support surface on a shaft.
Patent CA-2878057-A1 (CA)
Inventor: ALARGOVA ROSSITZA GUEORGUIEVA
IPC: A61K31/404
Filed: 2013-07-15
Abstract: A pharmaceutical composition comprising Compound 1, (R)- 1 -(2,2- difluorobenzo[d] [ 1,3]dioxol-5-yl)-N-( 1 -(2,3-dihydroxypropyl)-6-fluoro-2-( 1 -hydroxy-2- methylpropan-2-yl)- l H-indol-5-yl)cyclopropanecarboxamide, and at least one excipient selected from : a filler, a disintegrant, a surfactant, a glidant and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Methods for treating a patient in need thereof include administering the pharmaceutical composition of Compound 1 are also disclosed.
Patent CA-2878225-A1 (CA)
Inventor: YAMAMOTO MASAYA
IPC: H01M8/10
Filed: 2013-06-24
Abstract: [Problem] To provide a transfer method that can prevent transfer position offsetting and transfer failures for a catalyst layer and transfer the catalyst layer to an intended position on an electrolyte film. [Solution] The transfer method includes the following steps. Base materials (30, 32) and an electrolyte film (10) are laminated to each other such that catalyst layers (20, 22) formed on the base materials (30, 32) are in contact with the electrolyte film (10), and a laminate (50) is formed. Pressure is applied to the laminate (50) in the direction of lamination. The laminate (50) is heated to a first temperature. Application of pressure is started, and after a prescribed period of time has passed, heating is stopped. After the heating has been stopped and when the temperature of the catalyst layers (20, 22) has fallen to a second temperature, which is lower than the first temperature, or lower, the application of pressure is stopped.
Patent CA-2880577-A1 (CA)
Title: Ceiling clamp for recessed light mounting
Inventor: CLARK STEPHEN HOWARD
IPC: F21S8/02
Filed: 2015-01-28
Abstract: A lighting mount assembly and method are disclosed to mount a recessed light fixture in an opening in a wall. The lighting mount assembly includes a mounting frame, and at least two adjustable brackets which are movable relative to the mounting frame. The mounting frame and the brackets cooperate to clamp a portion of the wall from opposing sides. Each of the brackets also includes a resilient member, such as a leg spring, which can be engaged to and disengaged from a portion of a light fixture, such as a groove, to hold or release the recessed light fixture in the wall opening.
Patent CA-2880763-A1 (CA)
Inventor: BRIEN DAVID R
IPC: A63F13/28
Filed: 2013-09-10
Abstract: An electronic video poker machine configured to allow play of a defined series of hands of video poker. The electronic video poker machine comprises at least one display device, at least one input device, a memory and at least one computer processor configured to display at least a first hand and at last one subsequent hand of at least three cards. A player is provided a first hand of cards on the display. The player identifies which cards from the hand to hold using the input device. The remaining cards from the hand are discarded and draw cards are dealt to replace the discarded cards. The discarded cards are returned to the deck after the draw, making those discarded cards available for subsequent hands in the defined series of hands.
Patent CA-2880836-A1 (CA)
Inventor: NGUYEN CHRISTINE
IPC: D04H1/4266
Filed: 2013-07-25
Abstract: Le procédé comprend successivement une application d'une solution aqueuse contenant un liant dilué dans la solution,sur des fibres minérales ou végétales, une mise en forme des fibres en un matelas continu sur un con- voyeur en mouvement, et un chauffage du matelas en défilement dans une étuve par flux d'air chaud à une température supérieure à la température de durcissement du liant.En outre, est réalisé un séchage au moins partiel du matelas et préalable à l'entrée dans l'étuve. Ledit séchage au moins partiel inclut une irradiation du matelas en défilement au moyen d'ondes électromagnétiques radiofréquences dont la fréquence est située entre 3MHz et 300GHz.