Patent RU-2300883-C2 (RU)
Inventor: BARDEEV JURIJ FEDOROVICH
IPC: A61K31/00
Filed: 2005-08-29
Granted: 2007-06-20
Abstract: FIELD: veterinary science. 
     SUBSTANCE: the innovation deals with supplementing the diet with iodinated common salt and a medicinal preparation perorally as metronidasol and a preparation of sulfanyl amide group. Additionally, one should introduce a diuretic, and as medicinal preparation one should additionally use penicillin sodium salt intramuscularly and 0.5%-metronidasol solution intravenously. Moreover, for pregnant cows of dairy herd the preparations should be introduced once annually for the whole productive period in the following sequence: a 6-d-long course up to calving dealing with introducing metronidasol at the dosage of 1.5 g/animal and norsulfasol or sulfadimezine at the dosage of 1 g/animal. At calving day it is necessary to inject intravenously 0.5%-metronidasol solution at the dosage of 200 ml/animal thrice in 8 h. Since the 2 nd  to the 5 th  d inclusively it is important to introduce metronidasol perorally at the dosage of 2.5 g/animal and norsulfasol or sulfadimezine at the dosage of 1 g/animal. Since the 6 th  to the 15 th  d inclusively one should inject intramuscularly penicillin sodium salt at the dosage of 2 mln U/animal - twice daily. On the 16 th  d one should inject intravenously 0.5%-metronidasol solution at the dosage per 200 ml/animal thrice in 8 h. With prophylactic purpose for stud bulls it is necessary to introduce preparations twice annually at 6-mo-long intervals according to the following scheme: during the 1 st  and the 2 nd  d - intravenously 0.5%-metronidasol solution at the dosage of 300 ml/animal thrice at 8-10-h-long interval. Since the 3d to the 5 th  d inclusively - perorally metronidasol at the dosage of 2.5 g/animal and norsulfasol or streptocid at the dosage of 2 g/animal. Since the 6 th  to the 15 th  d - intramuscularly penicillin sodium salt at the dosage per 3 mln U/animal twice daily. On the 16 th  d - intravenously 0.5%-metronidasol solution at the dosage of 300 ml/animal thrice in 8 h. With prophylactic purpose for cattle youngsters the preparations should be introduced starting since 1-mo age according to the following scheme: during the 1 st  d - intravenously 0.5%-metronidasol solution at the dosage of 10 ml/animal thrice at 8-10-h-long interval. During ten days - perorally metronidasol at the dosage of 0.125 g/animal and norsulfasol at the dosage of 0.5 g/animal once daily. On the 13 th  and the 14 th  d - intravenously 0.5%-metronidasol solution at the dosage of 10 ml/animal thrice at 8-10-h-long interval, for 4-mo-aged calves during the first 2 days - intravenously 0.5%-metronidasol solution at the dosage of 20 ml/animal thrice at 8-10-h-long interval. During 18 days - perorally metronidasol at the dosage of 0.5g/animal and norsulfasol at the dosage of 0.5g/animal once daily, for 6-mo-aged calves  during 10 days running - intramuscularly penicillin sodium salt at the dosage of 500 thousand U/animal twice daily. For 12-mo-aged calves during the first 2 days - intravenously 0.5%-metronidasol solution at the dosage of 100 ml/animal thrice at 8-10-h-long interval, since the 3d to the 5 th  d inclusively - perorally metronidasol at the dosage of 1 g/animal and norsulfasol or streptocid at the dosage of 1 g/animal once daily, since the 6 th  to the 12 th  d inclusively - intramuscularly penicillin sodium salt at the dosage of 1 mln U/animal twice daily. For 17-mo-aged calves during the first 2 days - intravenously 0.5%-metronidasol solution at the dosage of 150 ml/animal thrice at 8-10-h-long interval; since the 3d to the 5 th  d - perorally metronidasol at the dosage of 1.5 g/animal and norsulfasol at the dosage of 1 g/animal; for 18-mo-aged calves before pairing for 10 d - intramuscularly penicillin sodium salt at the dosage of 1 mln U/animal twice daily. The innovation is of high efficiency and enables to shorten the terms of therapy along with widened groups of animals under treatment and increased action of medicinal preparations. 
     EFFECT: higher efficiency. 
     3 cl