baber/WOPTO huggingface dataset:
Patent AU-746402-B2 (AU)
Title: Vectors having enhanced expression, and methods of making and uses thereof
Inventor: TARTAGLIA JAMES
IPC: A61P37/04
Filed: 1998-02-13
Granted: 2002-05-02
Abstract: Disclosed and claimed are vectors having enhanced expression and methods for making and using them. Enhancement of expression is from substantially cotemporal expression of at least one first nucleic acid molecule and at least one second nucleic acid molecule. The second nucleic acid molecule encodes a transcription factor or a translation factor or a transcription factor and a translation factor. The contemporaneous expression can be from operably linking the first and second nucleic molecules to a single promoter, or from operably linking the first nucleic acid molecule to a first promoter and the second nucleic molecule to a second promoter wherein the first and second promoters function substantially contemporaneously. Thus, the first and second nucleic molecules can be at the same locus in the vector, or at different loci. The second nucleic acid can encode: one transcription factor or more than one transcription factor; or one translation factor or more than one translation factor; or at least one transcription factor and at least one translation factor. The transcription factor can be from vaccinia H4L, D6, A7, G8R, A1L, A2L, H5R, or combinations thereof. The translation factor can be from a K3L open reading frame, an E3L open reading frame, a VAI RNA, an EBER RNA, a sigma 3 open reading frame, a TRBP open reading frame, or combinations thereof. The vector can be a poxvirus such as an attenuated poxvirus, e.g., NYVAC, or ALVAC.
Patent AU-586286-B2 (AU)
Title: Pharmaceutical and dietary composition
Inventor: HORROBIN DAVID FREDERICK
IPC: A61K31/16
Filed: 1986-09-30
Granted: 1989-07-06
Abstract: A method of prevention or treatment of diabetic neuropathy and the other long term complications of diabetes mellitus including complications in the cardovascular system, kidneys and eyes wherein effective amounts of one or both of i) gamma-­linolenic acid and/or one or more of the metabolites of gamma-­linolenic acid (DGLA, AA, 22:4 n-6 or 22:5 n-6) and ii) 18:4 n-3 and/or one or more of the metabolites of 18:4 n-3 (20:4 n-3, 20:5 n-3, 22:5 n-3, 22:6 n-3) are administered against such complications as such or in the form of an ester, salt, amide or other derivative convertible in the body thereto, alone or in an acceptable pharmaceutical carrier or diluent.
Patent AU-697811-B2 (AU)
Title: Deallylation reagent and deallylation method using said reagent
Inventor: BERNARD JEAN-MARIE
IPC: B01J31/24
Filed: 1994-04-08
Granted: 1998-10-15
Abstract: PCT No. PCT/FR94/00397 Sec. 371 Date Feb. 22, 1996 Sec. 102(e) Date Feb. 22, 1996 PCT Filed Apr. 8, 1994 PCT Pub. No. WO94/24088 PCT Pub. Date Oct. 27, 1994The present invention relates to a reagent and to a process which are useful, when carrying out an organic synthesis, for cleaving an allylic group from a function which is protected with the latter. This reagent is defined in that it contains: a) a solvent system; b) a catalyst containing at least one element from column VIII of the Periodic Table of the Elements, the said element from column VIII of the Periodic Table being coordinated with at least one coordination agent which is soluble in the said solvent system; c) a compound which is at least partially soluble in the said solvent system and which contains at least one nucleophilic function. Application to organic synthesis.
Patent AU-709584-B2 (AU)
Title: Industrial production process for a vaccine against Japanese encephalitis, and vaccine obtained
Inventor: FANGET BERNARD
IPC: A61K39/00
Filed: 1996-07-29
Granted: 1999-09-02
Abstract: PCT No. PCT/FR96/01195 Sec. 371 Date Aug. 13, 1998 Sec. 102(e) Date Aug. 13, 1998 PCT Filed Jul. 29, 1996 PCT Pub. No. WO97/04803 PCT Pub. Date Feb. 13, 1997A method is disclosed for industrially producing a Japanese encephalitis vaccine, wherein (a) cells from a cell line are cultured, (b) the resulting cell culture is inoculated with a Japanese encephalitis virus in the presence of a viral growth medium, (c) the virus is propagated and multiplied on the cells, (d) the viral growth medium is recovered in the form of a suspension of viruses produced by the cells, (e) the virus suspension is purified in at least one ion exchange chromatography step and a gel permeation step, and (f) the virus suspension is formulated and converted into a pharmaceutical form to preserve it until the moment of use. A Japanese encephalitis vaccine characterised in that it comprises a Japanese encephalitis virus produced by culturing cells from a cell line, and in that the cellular DNA content is less than 100 pg/dose, is also disclosed.
Patent AU-768783-B2 (AU)
Title: Synthesis of substituted pyrazolopyrimidines
Inventor: GROSS RAYMOND S
IPC: C07C233/43
Filed: 2000-08-10
Granted: 2004-01-08
Abstract: Methods of making substituted pyrazolopyrimidines generally and, more particularly, N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-alpha]-pyrimidin-7-yl}phenyl)acetamide. Such compounds have utility over a wide range of indications, including treatment of insomnia. In the practice of the present invention, improved techniques which do not require use and/or isolation of the pyrazole intermediate are disclosed, as well as improved techniques for making the reaction intermediates themselves. Such techniques offer significant advantages, including enhanced efficiency, particularly in the context of large scale manufacture.
Patent AU-580471-B2 (AU)
Title: Oxygen blast nozzle
Inventor: BOCK ANDRE
IPC: C21C5/46
Filed: 1987-02-25
Granted: 1989-01-12
Abstract: A nozzle for the refining of metals by oxygen blasting from above the melt is presented. The nozzle includes a nozzle head having a blast pipe therethrough upstream of the mouth of the nozzle. The blast pipe directs a jet of gas comprised, at least in part, of oxygen, having a supersonic speed onto the melt. The blast pipe includes an inner tube. The lower portion of the inner tube has a throat positioned between a convergent and divergent sections, this lower portion defining a laval nozzle. The blast pipe also includes an outer tube coaxial with the inner tube and having a greater cross section than the inner tube. The mouth of the inner tube is spaced back (downstream) from the mouth of the blast pipe. The inner and outer tubes are each provided with flow control valves, and are connected to sources of pressurized gas. Devices are provided to vary the cross sectional area of the mouth of the inner tube. This device may consist of a needle shaped member, displaceable along the longitudinal axis of the inner tube, with the pointed portion of the needle movable between different positions within the convergent section of the inner tube.
Patent AU-702010-B2 (AU)
Title: Surgical cassette loading and unloading system
Inventor: ZALESKI RICHARD L II
IPC: A61M1/00
Filed: 1996-10-16
Granted: 1999-02-11
Abstract: The system for loading and unloading a surgical cassette having a peristaltic pump tube from a cassette receiving portion of a surgical console, comprises a peristaltic pump roller head having a flared and bevelled notch, the roller head being located in the cassette receiving portion of the surgical console. There is an extendable cylinder within the cassette receiving portion of the surgical console aligned so as to engage the peristaltic pump tube.
Patent AU-767073-B2 (AU)
Title: Method for producing a dental prosthesis
Inventor: FRANK SYBILLE
IPC: A61C13/00
Filed: 2000-08-16
Granted: 2003-10-30
Abstract: The invention relates to a method for producing a dental prosthesis comprising the following steps: a) preparing a blank; b) machining the blank using milling methods; c) dense sintering the blank at a temperature ranging from 1200 to 1650  DEG C, whereby the blank comprises a presintered material and has a raw resistance to breaking ranging from 15 to 30 Mpa.
Patent AU-609717-B2 (AU)
Title: Plant generation method
Inventor: HUNTER CLIFFORD PAUL
IPC: A01G7/00
Filed: 1987-05-13
Granted: 1991-05-09
Abstract: The invention provides a method of generating barley plants comprising culturing barley microspores on a sugar-containing medium and harvesting green plantlets from the medium characterised in that the sugar in the sugar-containing medium is at least one sugar selected from sucrose; glucose; and oligosaccharides and polysaccharides containing at least two glucose residues; wherein the concentration of sucrose and glucose in the medium is not greater than 0.03 mol/l; and a method of generating barley seed which comprises the additional steps of cultivating green plantlets and deriving seed from resulting mature plants.
Patent AU-771374-B2 (AU)
Title: Coating materials
Inventor: TAYLOR ALAN
IPC: C08J7/046
Filed: 2000-09-22
Granted: 2004-03-18
Abstract: A process for providing a protective coating on a substrate comprises (1) applying to the substrate a coating composition comprising a homogenous mixture comprising an inorganic sol and polymerisable organic species, the inorganic sol being obtainable by hydrolysing hydrolysable inorganic monomer precursors to form inorganic monomers; (2) polymerising the polymerisable organic species; and (3) polymerising the inorganic monomers, wherein polymerisation of the organic monomers is initiated prior to completion of polymerisation of the inorganic monomers, to form a solid coating on the substrate. The resulting coating comprises interpenetrating inorganic and organic polymer networks, and may be formulated to be transparent. It is useful in the protection of a wide variety of substrates, and in particular for providing scratch/abrasion resistance to low melting point plastics materials such as polycarbonates and polyacrylates.
Patent AU-610496-B2 (AU)
Title: Photochromic spiropyran compounds
Inventor: HELLER HARRY GEORGE
IPC: C07D407/04
Filed: 1987-05-15
Granted: 1991-05-23
Abstract: A series of novel photochromic spiropyrans are disclosed in which a spiro-adamantane group is introduced into the 2-position of the benzopyran or naphthopyran ring. The spiropyran compounds of the invention exhibit heliochromic properties, i.e. they colour in sunlight and fade rapidly at ambient temperatures in the absence of U.V. light, making them good candidates for use in the manufacture of sunglasses. The invention includes lenses which darken in sunlight and incorporate the novel spiropyrans and a process for the preparation of the spiropyran compounds.
Patent AU-680548-B2 (AU)
Title: Detection and speciation of (campylobacter)
Inventor: FOX ANDREW JOHN
IPC: C12Q1/689
Filed: 1994-09-09
Granted: 1997-07-31
Abstract: Method for detecting Campylobacter by PCR detection of DNA sequence highly conserved between species lari, coli, jejuni and upsaliensis. Speciation between these four is possible as the PCR product is differentially cleaved by restriction endonucleases.
Patent AU-601513-B2 (AU)
Title: Digital audio companding and error conditioning
Inventor: WALKER GORDON KENT
IPC: H04H20/88
Filed: 1987-09-16
Granted: 1990-09-13
Abstract: A system for companding digital audio signal samples processes the digital audio signal samples to correct errors induced by the compression and expansion processes. These errors are calculated prior to compressing the samples. Such errors are calculated in accordance with a predetermined compression process and a predetermined expansion process; and the digital audio signal samples are corrected in accordance with such calculations prior to compression. The compression process includes providing a 3-bit gain word for a block of 70 samples. The gain word is computed in accordance with the position of the most significant "1" bit in the sample(s) having the peak magnitude. Each individual sample is processed in accordance with the block gain word to compress the sample by reducing the number of magnitude bits. The error calculation process includes calculating an error signal by subtracting a calculated reproduced digital audio signal sample from the digital audio signal sample to be compressed, filtering the error signal by noise-spectral filtering and adding the filtered error signal to the next-providing digital audio signal sample to provide a corrected digital audio signal sample for compression. The error calculation process also includes calculating an error value based upon the effect of using a single gain word for compressing a block of samples. The error value is subtracted from the corrected digital audio signal sample prior to compression. The gain word is forward error corrected by (5,1) encoding to enable detection and correction of both single-bit and double-bit errors in transfer by majority voting. The sign bit and the most significant magnitude bits of the compressed samples are forward error corrected to enable detection and correction of single-bit errors in transfer and to enable detection and concealment of double-bit errors in transfer.
Patent AU-741216-B2 (AU)
Title: Phenethylamine derivatives
Inventor: KOTAKE KEN-ICHIRO
IPC: C07K5/08
Filed: 1998-08-14
Granted: 2001-11-29
Abstract: Compounds represented by general formula (1) which are phenethylamine derivatives exhibiting a motilin receptor antagonism etc. and being useful as drugs, wherein A represents an amino acid residue, etc.; R1 represents R6 -CO-, etc.; R2 represents hydrogen, etc.; R3 represents -CO-R7 , etc.; R4 represents alkyl, etc.; R5 represents hydroxy, etc.; R6 represents alkyl, etc ; and R7 represents amino, etc. <CHEM>
Patent BG-60270-B2 (BG)
Title: Process for the preparation of 5h-2,3 benzodiazepine derivatives
Inventor: KOEROESI JENOE
IPC: C07D311/76
Filed: 1979-10-18
Abstract: By the method, 5H-2,3-benzodiazepin derivatives and their acid addition salts as well as pharmaceutical compositions thereof are prepared. The compounds have a general formula of and are produced when a mineral acid is added after the reaction between the charing substance and a hydrazine compound. The obtained compound of general formula I is converted into another compound by alkylation, aralkylation, acylation, reduction, oxidation and/or decarboxylation, and/or, if desired a free base of the general formula I is converted into a pharmaceutically acceptable acid addition salt or a salt of 5H-2, 3-benzodiazepin derivative of the general formula I is converted into the free base or into another acid addition salt.
Patent BG-60723-B2 (BG)
Title: Device for decreasing the carbon monoxide emitted from internal combustion engines
Inventor: MARINOV GEORGI E
IPC: F02M25/00
Filed: 1983-02-11
Abstract: The device consists of an electrolyte box (1) having electrolytic solution and carbon electrodes (5) connected to a storage battery (18) across a contact switch (15) and breaker (14) which is mounted above the accelerator pedal. A vessel (2) is fitted next to the electrolyte box containing a mixture of water from 30 to 50 vol.% and methylated (ethylated) alcohol or acetone. Inlet pipes (6 & 7) are housed in the electrolyte box, the other ends of which are connected through a disrtibutor (16) to a common inlet pipe (8) for hot air from the engine. Outlet pipes (9 & 10) are fitted above the level of the solutions in the electrolyte box (1) and vessel (2), the other ends of which are connected through a distributor (17) to a common outlet pipe (12). Distributors (16 & 17) are directly coupled to a balancing pipe (11) and an adjustment valve (13).
Patent DE-1815798-B2 (DE)
Title: Method of consolidating an incompetent earth formation - penetrated by a well
IPC: E21B33/138
Filed: 1968-12-19
Abstract: Method of consolidating an incompetent earth formation penetrated by a well.. by injecting into the formation (1) an aqueous solution of an activating agent (esp. Pd, Pt, Au, Ru, Rh and Sn2+ chloride, bromide, nitrate, sulphate or mixtures thereof). (2) an aqueous solution containing a catalytic metal-plating compound (esp. Ni and/or Co compounds) and a reducing agent (esp. hypophosphorus acid, alkali metal hypophosphite, alkali metal molybdenate, a lower aldehyde and mixtures thereof) in an amount sufficient to displace (1) and to flow a plurality of pore volumes through the formation. (3) a solution containing a non-catalytic compound (esp. Cu, Pb, Fe and Cd compounds) to achieve consolidation of the formation, and (4) reinjecting solution (2). Process has advantages of providing a binding agent which is resistant to hot water and steam and can withstand high pressures, strains and stresses.
Patent DE-2157211-B2 (DE)
Title: Lighting unit coupling sleeve - to connect pedestal shaped holding unit to lamp with lead guide passing through a socket
IPC: F21V21/26
Filed: 1971-11-18
Abstract: Coupling connecting a lighting unit to a pedestal shaped holding unit. The coupling sleeve is made as a second coupling link on the stand side for a plug-in connection of a socket fitted as a connecting link at one end of an upright pipe the other end of which is connected to the stand. The socket has a plug pin section with an axially adjoining tie attachment. A lead guide is located inside passing through the socket axially and produces as a staged bore. The larger bore section in diameter is made as an interior thread to screw in the upright pipe.
Patent FR-2597145-B2 (FR)
Inventor: FAURE ALAIN
IPC: E05C9/04
Filed: 1986-04-11
Granted: 1991-10-11
Abstract: 1. Espagnolette for recessing in the stile of the leaf of a window, french window or similar, comprising a case (2) in one piece with a faceplate (5), two locking rods (7) and (8) moving in opposite directions, disposed in the same alignment and flat against the inner face (4) of the faceplate (5), a mechanism comprising a spindle hole (6), presenting a salient part (26) traversing an opening (27) made in the faceplate (5), constituting a deadlock and directly operating the first locking rod (7), the extremity (9) of the first locking rod (7) being disposed along the inner face of the case (2), while the extremity (10) of the second locking rod (8) is returned against the bottom (12) of the case (2), characterized by the fact that the salient part (26) of the spindle hole (6) is disposed laterally in relation to the extremity (9) of the first locking rod (7) and by the fact that the spindle hole (6) indirectly operating, via a reversing element (16), the second locking rod (8), comprises a boby (14) partially housed in the extremity (10) of the second locking rod (8).
Patent IE-S65384-B2 (IE)
Title: High output cooking and water heating appliance
Inventor: STACK MICHAEL
IPC: F24B5/08
Filed: 1994-03-15
Abstract: A high output cooking and water heating appliance includes a cooker 10 containing an oven 12, 13, a hot plate and a water boiler 64. Two burners 35, 36 direct heat into the appliance, one, a high output burner 35, towards the boiler 64, and the other, a lower output burner 36, towards the cooking appliance. Separate fans 33, 34 supply air to the burners 35, 36 by conduits 43, 44. Associated with each burner 35, 36 is a fuel pump 37, 37A and an electrical control apparatus 38, 38a. The fans 33, 34 are located towards the rear of the appliance within a plenum base 31.
Patent JP-H0596-B2 (JP)
IPC: B01J23/22
Filed: 1982-02-23
Abstract: For the catalytic reaction of 3-methylpyridine with ammonia and oxygen to form 3-cyanopyridine there are used compounds of the elements antimony, vanadium, and oxygen and at least one of the elements iron, copper, titanium, cobalt, manganese, and nickel, whereby the atomic ratio of antimony to vanadium is greater than 1 and which contain besides these compounds a lattice layer silicate and a highly dispersed silica. These catalysts are very selective and result in high yields and high space-time-yields.
Patent JP-3088818-B2 (JP)
IPC: E04G9/10
Filed: 1992-02-19
Granted: 2000-09-18
Abstract: The invention relates to flat steel concrete anchors for precast concrete parts, which customarily comprise a connecting region, lying close to the surface of the precast concrete part and having an opening for a hoist, and an anchoring region, lying deeper in the precast concrete part and possessing, at at least one point, portions which project from the plane of the flat steel and through which saddle-mounting faces directed substantially transversely with respect to the loading direction are formed for the concrete. These projecting portions are formed by hook-shaped bends which are at the same time intended to grip round reinforcement bars or secondary reinforcement bars. As a result of this shape, the flat steel concrete anchors are dependent, with respect to their position, on the direction of the secondary reinforcement bar, which can lead to problems in particular with very narrow concrete parts. The flat steel concrete anchor is to be provided in the anchoring region of the flat steel with an opening (5), beside which run lateral webs (6, 7) which are arched in opposite directions out of the plane of the flat steel by deformation. As a result of this shape, the opening is to have, in addition to the opening cross-section existing orthogonally to the flat steel plane, also an opening cross-section parallel to the flat steel plane. 
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Patent JP-H0218303-B2 (JP)
IPC: C04B14/48
Filed: 1982-03-03
Abstract: A steel block is subjected to cutting in a direct manner to produce steel fibres for reinforcing concrete. The said fibres are flat in shape and satisfy the following predetermined conditions:- if L is the length of a steel fibre, W is its width, t is its thickness, and N = W/t is the flatness index; then, L is 20 to 40 mm, N = W/t is 7 to 9, W is 1.5 to 2.5 mm, and t is 0.2 to 0.3 mm.
Patent JP-H0112956-B2 (JP)
IPC: F02B1/04
Filed: 1981-04-20
Abstract: A rotary vacuum pump is proposed, having a rotor with vanes which rotates eccentrically within a housing bore. Each vane is coupled with a body which is ineffective at relatively low pump rpm; however, at higher rpm, the body engages the vane in such a manner that it removes the vane from its track within the housing bore. In this manner, an rpm-dependent shutoff device is created for the pump. In cooperation with the furnishing of underpressure as an auxiliary pressure in motor vehicles, the pump is used to supplement the underpressure which prevails when the internal combustion engine is at low, idling rpm; this prevailing underpressure is at a very low pressure level, and so when it is thus supplemented there is sufficient auxiliary vacuum force available over the entire rpm range.
Patent JP-3495411-B2 (JP)
IPC: B60R19/34
Filed: 1994-04-14
Granted: 2004-02-09
Abstract: An energy absorbing device (10, 80, 100) for use alongside a roadway to decelerate an impacting vehicle includes first and second elements. The first element (18, 82, 108) extends in an axial direction and includes a multitude of projecting elements (28, 86, 110). The second element (26, 88, 102) is movable relative to the first element (18, 82, 108) in the axial direction, and the first and second elements (18, 82, 108; 26, 88, 102) are sized to create an interference fit such that relative axial movement of the second element (28, 86, 110) applies a shear load to the first element (18, 82, 108) to progressively deform successive ones of the projecting elements (28, 86, 110) . This progressive deformation of the projecting elements (28, 86, 110) retards relative axial movement between the first and second elements (18, 82, 108; 26, 88, 102). <IMAGE>
Patent JP-2758341-B2 (JP)
IPC: B41F23/08
Filed: 1993-04-05
Granted: 1998-05-28
Abstract: The invention relates to a method and a device for varnishing and perfecting sheets in a varnishing and perfecting unit. The object of the invention is to develop a method and a device, which allow perfecting and partial varnishing of sheets in a varnishing unit. This is achieved in that the sheet (6), after transfer from the feed drum (2) to the back pressure cylinder (3), receives a return print on the underside of the sheet in the printing zone (7). Subsequently, the partial varnishing takes place on the face side in the region of the printing zone (8). In this case, the feed drum (2) consists of at least one cylindrical back pressure segment which is arranged on the shaft by means of clamping elements. 
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