baber/WOPTO huggingface dataset:
Patent DE-69733884-D1 (DE)
Inventor: BROCARD BERTRAND
IPC: C12N9/00
Filed: 1997-02-20
Granted: 2005-09-08
Abstract: A DNA fragment coding for a modified nuclear glucocorticoid receptor, particularly one mutated in the region coding for the ligand binding domain, so that receptor activity is more strongly inducible by a synthetic glucocorticoid ligand than by a natural glucocorticoid ligand, is disclosed. A recombination system inducible in mammals by means of a fusion protein produced between a recombinase and the binding domain of the ligand derived from the modified glucocorticoid receptor of which the activity is more strongly inducible by synthetic glucocorticoids than by natural glucocorticoids, is also disclosed.
Patent DE-69736835-D1 (DE)
Inventor: NOVICK DANIELA
IPC: C12P21/08
Filed: 1997-04-29
Granted: 2006-11-30
Abstract: Antibodies directed against the ligand binding component of the interferon-±/² receptor are provided, which are capable of selectively modulating the activity of various type-I interferons.
Patent DE-69809242-D1 (DE)
Inventor: KINDON NICHOLAS
IPC: A61K31/505
Filed: 1998-07-15
Granted: 2002-12-12
Abstract: The invention relates to new pharmaceutically active compounds which are are P2-purinoceptor 7-transmembrane (TM) G-protein coupled receptor antagonists, compositions containing them and processes for their preparation.
Patent DE-69822360-D1 (DE)
Inventor: BOUGAMONT JEAN-LOUIS
IPC: B65D23/00
Filed: 1998-04-02
Granted: 2004-04-22
Abstract: The container has a top (E) with an inner duct (1) linked to the container at one end and to an outlet (10) at the other. The duct is at least partially closed by an insert (2) with a selective porosity which permits a controlled flow of the product outwards on the one hand and a filtration of indrawn air on the other, holding back contaminants and/or biological pollutants. The top is covered by a protective cap (3) with a seal for the outlet (10), e.g. in the form of an inner seal lip (30) which fits round the outlet, or a projection which fits into the outlet aperture when the cap is put in place over the top.
Patent DE-69825426-D1 (DE)
Inventor: BOARD B
IPC: G01H1/00
Filed: 1998-02-17
Granted: 2004-09-09
Abstract: For automatically predicting machine failure a transducer sensor, such as piezoelectric crystal, is applied to a machine for sensing machine motion and structure-borne sound, including vibration friction, and shock waves. The structure-borne sound and motion sensed is converted to electrical signals which are filtered to leave only the friction and shock waves, which waves are processed, as by detecting the envelope and integrating beneath the envelope, resulting in a measure of friction and shock wave energy, i.e., stress wave energy. This measure is computed and processed for producing fault progression displays for periodic and aperiodic damage. This is accomplished in a personal computer, menu-driven environment.
Patent DE-69833197-D1 (DE)
Inventor: SCHUELEIN MARTIN
IPC: C12N15/09
Filed: 1998-07-01
Granted: 2006-04-06
Abstract: A xyloglucanase having a relative xyloglucanase activity of atleast 50% at pH7 and either no or an insignificant cellulolytic activity is obtainable e.g. from a strain of Bacillus. A xyloglucanase comprising an amino acid sequence as shown in positions 30-261 of SEQ ID NO:2 or homologues may be derived from e.g. Bacillus licheniformis, ATCC 14580, and may be encoded by polynucleotide molecules comprising a nucleotide sequence as shown in SEQ ID NO:1 from nucleotide 88 to nucleotide 783; and a xyloglucanase comprising an amino acid sequence as shown in positions 1-537 of SEQ ID NO:4 or homologues may be derived from e.g. B. agaradhaerens, NCIMB 40482, and may be encoded by polynucleotide molecules comprising a nucleotide sequence as shown in SEQ ID NO:3 from nucleotide 1 to nucleotide 1611. The xyloglucanases are useful e.g. in cleaning compositions and for treatment of cellulosic fibres.
Patent DE-69838887-D1 (DE)
Inventor: DYKES CHARLES D
IPC: B22D11/06
Filed: 1998-03-02
Granted: 2008-01-31
Abstract: Steering, tensioning and driving a revolving metallic casting belt in continuous casting machines wherein the belt travels along a generally straight casting plane  P . Two two-axis robotic mechanisms are positioned at opposite ends of an exit-pulley drum, each including a "floating" housing carrying a bearing rotatably supporting a journal at the respective drum end. A drive connected to one of the journals rotates the drum for revolving the belt. The robotic mechanisms adjustably position opposite ends of a rotating drum in  X--X  plane parallel with plane  P  for tensioning the belt and in  Y--Y  plane perpendicular to plane  P  for steering the revolving belt. These robotic mechanisms are controlled to operate in any of several modes: (1) "Walking-tilt" steering keeps the belt much closer to an exiting product than prior art, the belt being flatter and in better contact with the product for improving casting speed and quality. Mode (2) provides a "virtual squaring shaft" causing a drum to simulate being constrained by a rigid mechanical squaring shaft for synchronizing downstream movements of both drum ends for regularizing tension fully across a "cylindrical" casting belt. In modes (3), (4) and (5) the rigidity of the virtual squaring shaft may be "softened," or re-zeroed or eliminated, to accommodate small "frustro-conical" errors in belt manufacture. Moreover, even a small error in built-in length dimensions of a belt carriage may effectively be canceled by mode adjustments which effectively "twist" the virtual squaring shaft.
Patent DE-69839305-D1 (DE)
Inventor: KATO KANEYOSHI
IPC: C07D295/08
Filed: 1998-02-26
Granted: 2008-05-08
Abstract: A compound of the formula: wherein Ar is an aromatic ring assembly group which may be substituted or a fused aromatic group which may be substituted; X is (i) a bond, (ii) -S-, -SO- or -SO<SUB>2</SUB>-, (iii) C<SUB>1-6 </SUB>alkylene, C<SUB>2-6 </SUB>alkenylene or C<SUB>2-6 </SUB>alkynylene, etc., (iv) -CO-O- or (v) -(CH<SUB>2</SUB>)p-X<SUP>1</SUP>-, -(CH<SUB>2</SUB>)p-X<SUP>1</SUP>-CH<SUB>2</SUB>)q-, -(CH<SUB>2</SUB>)r-CO-X<SUP>1</SUP>-, -SO<SUB>2</SUB>-NR<SUP>8</SUP>- or -(CH<SUB>2</SUB>)r-SO<SUB>2</SUB>-NR<SUP>8</SUP>- wherein X<SUP>1 </SUP>is O or NR<SUP>8</SUP>, R<SUP>8 </SUP>is H, a hydrocarbon group which may be substituted or an acyl, p is 0 to 5, q is 1 to 5, p+q is 1 to 5, and r is 1 to 4; Y is a divalent C<SUB>1-6 </SUB>aliphatic hydrocarbon group optionally containing O or S, which may be substituted; R<SUP>1 </SUP>and R<SUP>2 </SUP>each is H or a lower alkyl which may be substituted, or R<SUP>1 </SUP>and R<SUP>2 </SUP>form a N-containing heterocyclic ring which may be substituted; Ring A is a benzene ring which may be further substituted; and Ring B is a 4- to 8-membered ring which may be further substituted, or a salt thereof has the effect of inhibiting amyloid-beta protein production and/or secretion and is useful as a pharmaceutical composition for preventing and/or treating the neurodegenerative disease, etc.
Patent DE-69840360-D1 (DE)
Inventor: FOSTER STEPHEN GEORGE
IPC: C12N1/15
Filed: 1998-02-23
Granted: 2009-01-29
Abstract: Potential fungicides can be identified by testing compounds in a 3-isopropylmalate dehydrogenase inhibition assay. Also disclosed is the use as a fungicide of a compound which is an inhibitor of 3-isopropylmalate dehydrogenase, mutants of Septoria nodorum disrupted in the 3-isopropylmalate dehydrogenase gene and amino acid sequences, derived from a Septoria nodorum gene coding for the enzyme 3-isopropylmalate dehydrogenase.
Patent DE-69900712-D1 (DE)
Inventor: HASZ JOHN R
IPC: F16F15/023
Filed: 1999-11-30
Granted: 2002-02-21
Abstract: A cup and piston squeeze film vibration absorbing support pad defines an annular squeeze film chamber (27, 36) and is provided with rolling bearings (21) (such as ball bearings) which hold the cup (11) and piston (40) separated to bear the vertical load while allowing limited relative motion transverse to the load bearing assembly by rolling on the bearings thereby damping horizontal vibration by squeeze film action. <IMAGE>
Patent DE-69906584-D1 (DE)
Title: Bimetallisches-metallocene katalysatorsystem für isotactische polypropylen-polymerisation
Inventor: RAZAVI ABBAS
IPC: C08F4/44
Filed: 1999-12-13
Granted: 2003-05-08
Abstract: A metallocene compound having the general formula: CpAXMQ1Q2Cp'A'X'M'Q1'Q2' wherein Cp and Cp' are each independently a substituted or unsubstituted cyclopentadienyl moiety; M and M' are each independently a metal chosen from Group IV B transition metals and vanadium, and coordinate to Cp and Cp' respectively; X and X' are each independently a substituted or unsubstituted Group VA or VIA heteroatom and coordinate to M and M' respectively; A and A' are bridging groups between Cp and X and between Cp' and X' respectively and are independently chosen from -SiR'2-O-SiR'2-, -SinR'm-, -CnR'm- and -CR'2-SiR'2-CR'2-SiR'2-, in which each R'is independently H or hydrocarbyl having 1 to 20 carbon atoms, n is an integer in the range 1 to 4 and m=2n; each Q1, Q2 and Q1' and Q2' is independently a coordinating group which is hydrogen, halogen or hydrocarbyl having 1 to 20 carbon atoms and each of Q1 and Q1' is coordinated to both M and M'.
Patent DE-69910491-D1 (DE)
Inventor: VAN NOY STEPHEN J
IPC: A61F9/00
Filed: 1999-03-17
Granted: 2003-09-25
Abstract: An intraocular lens injector cartridge (10, 110, 210) is provided having an asymmetric bore (18, 118, 218). The asymmetric bore initiates the folding of the lens (20) on one side (31) only, thereby reducing the amount of energy imparted to the lens and the potential for damage to the lens. The gentle folding of the lens also assists in positioning the travel of the haptics of the lens along the bore, thereby reducing the potential for damage to the haptics.
Patent DE-69911557-D1 (DE)
Inventor: CORDI ALEX
IPC: C07D233/10
Filed: 1999-12-17
Granted: 2003-10-30
Abstract: Imidazoline derivatives (I) are new. Imidazoline derivatives of formula (I) and their acid or base addition salts are new. R<9>-R<12> = H, 1-6C alkyl, 1-6C alkoxy, OH, 1-6C polyhalogenoalkyl, cyano, nitro, amino, 1-6C alkylamino, di-1-6C alkyl amino, thioalkyl, 1-6C sulfonylalkyl, 1-6C sulfinylalkyl, carboxy, alkoxycarbonyl, 1-6C alkylcarbonyloxy, formyl, carbamoyl, carboxamide, phenyl, benzyl or halo; B' = a group of formula (i) or (ii); X = CR<6>, CR<6>R<7>, N, NR<8>, O, S, SO or SO2; Z = C or CR<4>; R<4>, R<6>, R<7> = H or 1-6C alkyl; R<5>, R<8> = H, 1-6C alkyl or benzyl; Y' = CH, CH2 or a bond; R<1>-R<3> = H or 1-6C alkyl; or R<2> and R<4> or R<1> and R<4> = form a cyclopropane; and a, b = single or double bonds. Independent claims are also included for: (1) the preparation of (I); and (2) pharmaceutical compositions comprising at least one compound (I).
Patent DE-69917022-D1 (DE)
Inventor: BROENG JES
IPC: G02B6/02
Filed: 1999-05-21
Granted: 2004-06-09
Abstract: The present invention relates to a new class of optical waveguides, in which waveguiding along one or more core regions is obtained through the application of the Photonic Bandgap (PBG) effect. <??>The invention further relates to optimised two-dimensional lattice structures capable of providing complete PBGs which reflect light incident from air or vacuum. Such structures may be used as cladding structures in optical fibres where light is confined and thereby guided in a hollow core region. <??>In addition, the present invention relates to designs for ultra low-loss PBG waveguiding structures, which are easy to manufacture. <??>Finally, the present invention relates to a new fabrication technique which allows easy manufacturing of preforms for photonic crystal fibres with large void filling fractions, as well as a high flexibility in the design of the cladding and core structures. <IMAGE>
Patent DE-69923357-D1 (DE)
Inventor: LANG FRED D
IPC: F22B35/18
Filed: 1999-03-22
Granted: 2005-02-24
Abstract: The operation of a fossil-fueled thermal system is quantified by obtaining a reference fuel chemistry before on-line operation, and thereafter operating on-line. In on-line operation, a set of measurable operating parameters is measured, including at least effluent concentrations of O2 and CO2, and optionally the concentration of effluent H2O and the concentration of effluent SO2. An indicated Air/Fuel ratio is obtained, as are the ambient concentration of O2, and air pre-heater leakage and dilution factors. The fuel ash and fuel water are calculated, and the complete As-Fired fuel chemistry is calculated. From the complete As-Fired fuel chemistry, the pertinent systems parameters such as reference fuel heating value, boiler efficiency, system efficiency, fuel flow rate, total effluent flow rate, individual effluent flow rates, and individual emission rates are determined in a fully consistent manner. The Method has been reduced to software which is fully benchmarked and operational.
Patent DE-69923559-D1 (DE)
Inventor: DE REUSE HILDE
IPC: C12P21/08
Filed: 1999-06-29
Granted: 2005-03-10
Abstract: This application relates to methods of screening molecules capable of inhibiting the survival of Helicobacter pylori in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent H. pylori infection.
Patent DE-69923936-D1 (DE)
Inventor: GAYET THIERRY
IPC: F01P11/06
Filed: 1999-12-20
Granted: 2005-04-07
Abstract: The coolant loop comprises a radiator (12) that includes an inlet from the engine and an outlet to the engine. During the coolant replacement process, the device is connected between the coolant pumps (34,36) of the vehicle system. The new fluid is stored in a first reservoir (18). As the new fluid is pumped into the system, the old fluid is forced out into a second reservoir (20).
Patent DE-69927417-D1 (DE)
Inventor: NUZZI JOSEPH P
IPC: B26D1/12
Filed: 1999-08-20
Granted: 2006-02-02
Abstract: The present invention is a drilling system for cutting flat bottomed holes in work pieces. The tool has two opposing angled cutting edges extending from a rotational axis, with the inner portions of these cutting edges extending upwardly to create an overlapping web at the center. The overlapping web strengthens the center portion of the cuttings edges of the tool. The angle at which the inner portion of the cutting edge is inclined can be increased to create a center point on the cutting surface of the tool. The center point adds stability to the tool as it rotates along its longitudinal axis. The cutting edge has a rake surface with a positive rake angle that lessens the forces on the insert and also allows for better formation of chips of stock material being removed. Chip breakers can be cut into the cutting edges of the insert, further aiding in the removal of stock material.
Patent DE-69929876-D1 (DE)
Inventor: OHTOMO TOSHIHIKO
IPC: C12P21/02
Filed: 1999-02-25
Granted: 2006-04-20
Abstract: There are provided a genomic DNA comprising 4 exons encoding the amino acid sequence as set forth in SEQ ID NO: 2 and 3 introns ligating them, and a splicing variant of said genomic DNA; as well as a DNA having the base sequence as set forth in SEQ ID NO: 4 and a promoter activity and the fragment thereof, and uses thereof.
Patent DE-69941795-D1 (DE)
Inventor: AYESTARAN ALZUALDE JAVIER
IPC: E04C2/10
Filed: 1999-07-15
Granted: 2010-01-21
Abstract: Sandwich type board, for application in the construction field, of the type comprised of side and counterside, which has the following successive layers, from the center to the outside: a cellulose core impregnated in phenolic resin, a cellulose film impregnated in melamine, a laminated wood panel treated with phenolic resin, a tone package of one to three translucent and/or transparent films of cellulose, each of them impregnated in a resin to be chosen between melamine, melamine-acrylic, phenolic, melamine-phenolic, a multi-layer transparent/translucent acrylic film and a surface finish obtained by means of a demoulding film in the board press process.
Patent DE-502004003741-D1 (DE)
Inventor: SALAMEH RALF
IPC: F02F7/00
Filed: 2004-02-25
Abstract: The seal (5) is prepared by injection molding elastomeric material on to a carrier (4), which is preferably made of metal. The carrier (4) is then joined to the end section (2) of the plastic engine component while that component is injection molded. Alternatively the carrier (4) can be attached to a component with adhesive or mechanically, e.g. with bolts. Any heat treatment is carried out on the elastomer (5) and carrier (4) only. An independent claim is also included for a sealing assembly comprising an elastomeric seal (5) on a carrier (4) made by the described method. The carrier (4) can be a flat plate, a right-angle or U-shaped profile and it can have interlocking tongues for attachment during injection molding.
Patent DE-502004009179-D1 (DE)
Inventor: STEGMAIER HERMANN
IPC: B05D3/02
Filed: 2004-05-19
Abstract: A method for sinter coating a work-piece is disclosed, the work-piece having at least two sections of different surface-related heat capacities. The method includes a first step of pre-heating the work-piece to a first temperature that is higher than a fusion temperature of a sinter coating material. The method also includes a step of rapidly heating of the work-piece to a second temperature that is higher than the first temperature. However, the rapid heating step is halted before the temperature of the work-piece section with the greater surface-related heat capacity matches the second temperature. The work-piece then has a subsequent step of application of the sinter material to the work-piece. The step of shock heating of the work-piece is preceded by a step of pre-heating the work-piece under conditions which, with continuing effect on the work-piece, bring the work-piece under conditions which, with continuing effect on the work-piece, bring the work-piece to a second temperature between the fusion temperature of the sinter material and the first temperature.
Patent DE-502004009505-D1 (DE)
Inventor: EDLER GERHARD
IPC: B29C45/00
Filed: 2004-01-28
Abstract: The invention is based on an injection unit for the processing of fusible materials, for example thermoplastics, ceramic or metallic compositions or the like, in which at least two melt streams are fed via a channel system to one or more mould cavities in a sequence which changes with time. In accordance with the invention, only one rotating valve element is provided for each channel system which leads to the mould cavity (cavities) and consists of at least two feed channels ( 6; 7 ). The valve element consists of a hollow spindle ( 11 ), which is connected to the pressure channel ( 20 ) of the melt and has, in the plane of the feed channels ( 6; 7 ) leading to the mould cavity (cavities), at least one distribution channel ( 21 ) which runs radially outwards and is likewise connected to the pressure channel ( 20 ).
Patent DE-502005000876-D1 (DE)
Inventor: PIERONCZYK MARTIN
IPC: B60R25/0215
Filed: 2005-07-22
Abstract: A device for blocking the steering shaft of a motor vehicle against rotation by a locking bolt which can be axially moved back and forth between locked and released positions via a two-directionally rotatable control member, and comprises a locking element and an actuating element. The control member surrounds the actuating element and has two helically extending interior grooves and a planar end surface adjoining the grooves and extending perpendicular to the axis of rotation of the control member. A transverse pin axially displaced in the actuating element cooperates with the grooves and the end surface. A helical compression spring is supported on the actuating element via a plunger having an oblong hole through which the transverse pin extends, and which plunger can be axially displaced in the actuating element by a stop so that the helical compression spring presses the transverse pin against the end surface via the locking element and the actuating element in the released position of the locking bolt.
Patent DE-502005002598-D1 (DE)
Inventor: ROEHLING WILLMUT
IPC: F16D69/04
Filed: 2005-10-18
Abstract: The invention relates to a brake lining (1) comprising a lining support plate (2) which is provided with a friction lining (7) arranged on the surface thereof. A damper plate (3) is placed on the opposite to the friction lining (7) second face of the lining support plate (2). Said damper plate (3) comprises integrated anchoring elements (4) for preventing lateral sliding thereof, wherein said anchoring elements (4) pass through a recess embodied in the lining support plate (2) and are engaged with the friction lining (7). Damping layer (6) on which a brake piston can act during braking is disposed on the damper plate (3) opposite to the lining support plate (2). An adhesive layer (8) is applied between the damper plate (3) and the lining support plate (2) in such a way that the damper plate (3) is fixable to the lining support plate (2).
Patent DE-502005003724-D1 (DE)
Inventor: HUBER REINHOLD
IPC: A01D34/69
Filed: 2005-11-10
Abstract: The drive has a primary drive (7) driving two drive pulleys (10, 11), and two secondary belt drives (8) acting on a drive pulley (13). A switching device (9) for change over of drive direction is attached to the secondary belt drive, with which one of the drive pulleys (10, 11) is alternatively brought in to a working connection with a belt section (18) of the secondary belt drives.
Patent DE-502005005047-D1 (DE)
Inventor: CLAUSS ULRICH
IPC: E06B9/165
Filed: 2005-08-24
Abstract: The invention relates to roller blind slats having a profile which is shaped by flat sheet metal in a rolling step. A single-pieced roller blind body is associated with the roller blind slats. The roller blind body is formed with a slot on the underside thereof and a hooked strip is provided on the top edge thereof. The slot part is approximately 20% on the total surface of the roller blind slats.
Patent DE-502005005761-D1 (DE)
Inventor: LEHMANN PETER
IPC: A47L9/26
Filed: 2005-08-05
Abstract: The invention relates to a vacuum cleaner with an actuating element (17) for an electrical component (9), which is fixed in a mount (7) inside the vacuum cleaner and whose electrical contacts (10) are mechanically attached to a printed circuit board (11) and in order control at least one function of the vacuum cleaner, are connected in an electrically contacting manner to strip conductors of the printed circuit board (11). In order to keep actuating forces induced by actuating the actuating element away from the printed circuit board (11), the invention provides that the printed circuit board is held in an untensioned manner on the electrical contacts (10) of the electrical component (9) while being mechanically separate from the mount.
Patent DE-502005006172-D1 (DE)
Inventor: JAEGER ANSGAR
IPC: B29K105/06
Filed: 2005-10-14
Abstract: In a method for making long fiber-reinforced molded plastic parts, a continuous stand-reinforced melt is injected into a mold, after the latter has been closed, causing the mold to open until a predefined compression gap has been reached. The injection of long fiber-reinforced melt into the mold is continued and the mold is closed again. After permitting the long fiber-reinforced melt to cool down, the mold is opened and the end product removed. In this way, fibers can be introduced in a comparatively gentle manner into the mold and distributed therein, and fiber breakage and formation of surface marks are largely prevented.
Patent DE-502005006404-D1 (DE)
Inventor: STOMMEL WILFRIED
IPC: A47F5/05
Filed: 2005-07-14
Abstract: Each of several shelves (13) has several sector shaped segments (20). The segments move on race (12) by running gear (32). The running gear is formed as retainer for retaining the segment against radial removal from the race.