baber/WOPTO huggingface dataset:
Patent CR-20190487-A (CR)
Title: Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
Inventor: JAMES BENDER
IPC: C12N5/0783
Filed: 2018-01-05
Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
Patent CR-20210467-A (CR)
Title: Treatment of cancer with her2xcd3 bispecific antibodies in combination with anti-her2 mab
Inventor: Lutzker Stuart
IPC: C07K16/32
Filed: 2020-03-13
Abstract: The present invention provides methods of treating of HER2-positive cancers (such as HER2- positive breast cancer and HER2-positive gastric cancers) using HER2 antibodies, such as a combination of a HER2 T cell-dependent bispecific antibody (TDB) with an additional HER2 antibody (<em>e.g.</em>, trastuzumab).
Patent EC-SP066581-A (EC)
Title: Aparato y método para empaque de grava en boca de pozo
Inventor: DALE BRUCE A
IPC: E21B43/04
Filed: 2006-05-24
Abstract: Se divulgan un aparato y método para boca de pozo, para uso en una boca de pozo para terminación y producción. El aparato comprende un material exterior permeable en la boca de pozo que comprende una sección de primer tubo base con por lo menos una porción del tubo base perforada, el primer tubo base está dentro del material exterior permeable y por lo menos parte del tubo base perforado está diseñado para estar adyacente a un intervalo de producción; una sección de segundo tubo base con por lo menos una porción del segundo tubo base ranurada, el segundo tubo base está dentro del material exterior permeable y encima de la sección perforada de tubo base diseñada para estar adyacente al intervalo de producción, en donde por lo menos una porción del tubo base ranurado está diseñada para estar adyacente a una sección no productiva de la boca de pozo. El aparato para terminación de producción puede instalarse dentro de la boca de pozo para proporcionar redundancia contra fallas de filtro de pozo.
Patent EC-SP099724-A (EC)
Title: Uso de inhibidores de piridopirimidinona de pi3k-alfa en el tratamiento del cáncer
Inventor: LAMB PETER
IPC: A61K31/337
Filed: 2009-11-09
Abstract: La presente invención proporciona métodos de tratar cáncer por la administración de un compuesto de Fórmula I, opcionalmente en forma de sus sales farmacéuticamente aceptable, sus solvatos y/o hidratos, en combinación con otros tratamientos de cáncer
Patent EC-SP099752-A (EC)
Title: Polímeros reductores de fricción no polialfaolefina dispersas
Inventor: HARRIS WILLIAM F
IPC: C08J3/00
Filed: 2009-11-20
Abstract: Una composición reductora de fricción que comprende al menos un polímero no polialfaolefina que tiene un tamaño promedio de partícula en el rango de aproximadamente 5 a aproximadamente 800 micrómetros. El polímero no polialfaolefina inicialmente puede ser preparado por polimerización en emulsión. Las partículas poliméricas iniciales después pueden ser al menos parcialmente consolidadas y luego disminuidas en su tamaño y dispersadas en un portador de fluido. La composición reductora de fricción resultante puede ser añadida a un hidrocarburo que contiene fluido para disminuir el descenso de presión asociado con el flujo turbulento de un hidrocarburo que contiene fluido a través de un conducto.
Patent EC-SP930930-A (EC)
Title: Construccion de pisos para casos de excavaciones profundas o similares
Inventor: APPS WILLIAM PATRICK
IPC: B65D85/30
Filed: 1993-05-19
Abstract: El invento se refiere a la construción de un piso para cajas profundas ect, que se caracteriza por una serie de costillas octagonales espaciados entre si, una rejilla de costillas laterales y longitudinales que se cruzan entre las hileras y columnas adyacentes de las costillas octagonales; una rejillas de costillas y longitudinales que se extienden generalmente a través de los centros de cada uno de los octágonos, interconectados los actágonos y las costillas centrales, a fin de formar una construcción de enrejado segura y abierta, como sitio para contener las paredes.
Patent EC-SP972224-A (EC)
Title: Celulas inmortalizadas para cultivo de virus
Inventor: FOSTER LINDA C
IPC: C12N5/10
Filed: 1997-08-13
Abstract: Este invento se relaciona con la producción y utilización de linajes de células inmortalizadas obtenidas de fibroblastos primarios embrionarios de polos. LAS CÉLULAS SON ÚTILES A MANERA DE SUBESTRATOS PARA LA PROPAGACIÓN DE VIRUS, EXPRESIÓN DE PROTEINA RECOMBINANTE Y PRODUCCIÓN DE VIRUS RECOMBINANTE.
Patent EC-SP993113-A (EC)
Title: Mejoras en dispositivos para la conexión del pico de descarga y grifos en juegos de griferia en general
Inventor: VIEGENER FRANCISCO ENRIQUE
IPC: F16K5/00
Filed: 1999-08-24
Abstract: Dispositivos para la conexión de picos de descarga y grifos enjuegos de grifería sanitaria o lo similar, en los cuales el pico provee una base de asiento en el artefacto con un vástago tubular, boquilla o lo similar de fijación al mismo conectado a través de una pieza intermedia con la respectiva boquilla de salida del cuerpo valvular del grifo formado y aplicado aparte del pico, caracterizadas porque este dispositivo comprende, en la extremidad de dicho vástago del pico y como parte solidaria al mismo, una prolongación bajo la forma de una espiga también tubular, exteriormente cilíndrica pero ciega por su propio extremo, en sentido axil, sobre la cual está enchufada directamente una porción de dicha pieza de interconexión, que a modo de núcleo troncal de la misma provee una hembrilla en la que está inserta dicha espiga, con ajuste deslizable longitudinal y rotativamente con la junta entre ambos elementos sellada herméticamente por intermedio de un primero y segundo anillos elastoméricos retenidos en sendas gargantas de la espiga y ampliamente espaciados entre sí, comprendiendo entre ambos un tramo de la pared de la espiga en el cual provee por lo menos un orificio de entrada de fluido al conducto de dicho vástago del pico, presentando este vástago y dicha pieza de interconexión cooperantes elementos de tope axil capaces de establecer una posición límite de inserción - enchufe entre la espiga y la hembrilla, en la cual dicho orificio de entrada de la espiga comunica con un orificio de salida de fluido de un conducto de la pieza de interconexión proveniente del grifo, con los dos orificios ubicados entre ambos anillos, incluyéndose medios removibles de retención de dicha pieza de interconexión contra desenchufe de la misma respecto de la espiga del vástago del pico.
Patent EE-9800099-A (EE)
Inventor: GARRETT L SCOTT
IPC: C03B5/24
Filed: 1998-04-08
Abstract: Apparatus (10) for forming a cased glass stream having an inner core glass surrounded by an outer casing glass includes a first orifice (24) for receiving core glass from a first source (12). A second orifice (26) is vertically spaced beneath and aligned with the first orifice, and is surrounded by a chamber (30) that communicates with the second orifice through a gap between the first and second orifices. A spout (36) delivers casing glass from a second source (40) through a tube (32) to the chamber in such a way that glass flows by gravity from the first and second sources through the orifices to form the cased glass stream. Rate of glass flow through the second or casing glass source (40) is measured and compared with one or more preset limits (78). Rate of casing glass flow from the second source to the chamber surrounding the orifices is adjusted when rate of flow through the second source departs from the preset limit. In this way, a desired ratio of casing glass to core glass, and consequently the desired thickness of the casing glass layer, is automatically maintained.
Patent FI-20012210-A (FI)
Inventor: JAHKONEN PEKKA
IPC: H02M5/458
Filed: 2001-11-14
Abstract: The invention relates to an electric motor drive for operating an alternating-current motor. The electric motor drive comprises a frequency converter for controlling the motor, which frequency converter comprises a rectifier and an inverter implemented using semiconductor switches arranged in a bridge, and an intermediate circuit placed between the rectifier and the inverter and comprising a capacitor. According to the invention, the electric motor drive additionally comprises two regulating units, the first one of which contains an inductor unit provided at the input of the frequency converter and at the same time at the input of the rectifier, the inductors comprised in the unit being connected to each phase; and an intermediate circuit with a low-value capacitor, of the order of 50 muF, while the second one contains an auxiliary switch, to which the supply of electric power is arranged to occur via a safety relay, the auxiliary switch being so connected to selected semiconductor switches of the inverter bridge that the control signal for a selected semiconductor switch will pass via the auxiliary switch when the latter is in a conducting state; and a current measuring unit for measuring and/or monitoring the supply current to the electric motor.
Patent FI-20080111-A (FI)
Inventor: ETTALA PEKKA
IPC: G06Q/
Filed: 2008-02-14
Abstract: Call or call alarm terminating method and system in a mobile telecommunication system, whereby a user (caller, USER1) having a calling mobile telecommunication terminal device (MOBILE1) makes a call to another user (recipient, USER2) having a called mobile telecommunication terminal device (MOBILE2), wherein when one of the user has finished the call or call alarm desired media, like an advertisement, is displayed at the called and/or calling terminal display, wherein the user of the called or calling terminal device responds to the media by giving an input via the interface of the called or calling terminal device, the called or calling terminal device executes one or several operations based on the input from the user.
Patent FI-20115111-A (FI)
Inventor: HAKKARAINEN SIMO
Filed: 2011-02-03
Abstract: A system with an apparatus that moves on wheels along a track defined by rails, and comprises two opposite sides carried by two or more wheels. The apparatus comprises detectors, at least one detector in either side of the apparatus in a known spatial connection with a wheel for generating to the control unit a signal that represents a measured lateral distance of a specific part of the wheel from a rail. Signals received from detectors are associated with position data that represents a specific position along the track where the lateral distance of the specific part of the wheel from the rail was measured. Signals received from detectors in spatial connection with wheels in opposite sides of the apparatus are used to generate an indication that represents temporal dimensional compatibility of the apparatus and the track. An effective tool for advanced monitoring interoperability of the apparatus and the track.
Patent FI-20116080-A (FI)
Inventor: TAMMINEN JUSSI KALLE OLAVI
IPC: F04B49/06
Filed: 2011-11-02
Abstract: A method and controller for operating pumps wherein each pump is modelled by a QH model indicating a high-efficiency region, a high-H region and a high-Q region and a rotational speed limit. A controller dynamically maintains a current set of operating pumps and controls their rotational speed (n). In steady-state operation, wherein the pumps operate in the high-efficiency region and below the rotational speed limit, all pumps of the current set are controlled together. If the pumps operate in the high-Q region or beyond the speed limit, a new pump is added to the current set, started and brought to a speed that produces flow. A balancing operation (12-3) follows the pump addition operation, wherein the speed of the pumps of the current set are adjusted for equal heads. If the pumps operate in the high-H region, a pump is removed from the current set of pumps.
Patent FI-20200052-A (FI)
Title: Process to produce microfibrillated cellulose by impacts
Inventor: MAI ESTEVÃO FRIGINI
IPC: D21D1/20
Filed: 2020-08-10
Abstract: The present invention relates a process to produce microfibrillated cellulose and a microfibrillated cellulose produced according to such process. The fibrillated microfibrillated cellulose is obtained subjecting a cellulose fiber in a slurry of cellulose pulp to multiple mechanical impacts. The cycle may be repeated several times. Non-cutting bars disposed in a ring formation is the preferred method. Two rings concentrically arranged facing each other in high rotation transmit the kinetic energy to the fibers to provide the highly defibrillated microfibrillated cellulose.
Patent FR-1602904-A (FR)
Title: Gas density measuring appts
IPC: G01N9/20
Filed: 1968-07-25
Granted: 1971-02-22
Abstract: Improved apparatus is of the type using a horizontal rigid beam having a bulb at each end, one bulb surrounded by reference gas and the other bulb by test gas. The beam is supported at its centre of gravity to pivot about a horizontal axis and any tendency to pivot is opposed by electro-magnetic devices and measured to indicate the relative densities of the two gases. The electro-magnetic devices comprises an electro-magnet mounted so that its field is perpendicular to the magnetic field of permanent magent mounted on the beam. This construction reduces the inertia of the beam which previously carried electro-magnet coils.
Patent GB-1044594-A (GB)
Abstract: 1,044,594. Making magnetic recording &c. heads. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. Feb. 12, 1965 [Feb. 15, 19641, No. 6191/65. Heading G5R. To make heads similar to those described in Specification 1,031,280, a bar 17 is machined to a sector of a circle, truncated at 20, the sectorial angle alpha being 360‹/n; slices are assembled as in Fig. 8, using foil spacers 11 and fused glass or enamel to join them, after which the assembly is machined down to the line 23. A four-gap head may be made from slices from a square bar (Figs. 5, 6, not shown). The heads may be magnetically separated by slots 24, a slot being cut in the bar, Fig. 7, and the gap depths may be limited by machining recesses 25 out of one of the contacting faces 19. U-form members carrying windings may be attached as in Specification 1,031,280.
Patent GB-1051107-A (GB)
IPC: F01L1/18
Abstract: 1,051,107. J. C. engine valve gear. FORD MOTOR CO. Ltd. Oct. 12, 1965, No.43153/65. Heading F1B. In valve gear having a rocker arm 3 pivotally mounted on a spherical seating 5 carried by a cylinder-head-mounted stud 4, the rocker arm is formed with two spaced depending portions 3a which restrict the rotation of the rocker arm about the stud. In a modification the stud is replaced by a bolt which is an interference fit in a tapped hole in the cylinder head. The rocker arm may be formed as metal pressing or as a casting.
Patent GB-1052388-A (GB)
IPC: C08G79/025
Abstract: 1,052,388. Laminates. UNILEVER Ltd. March 24, 1965 [Jan. 10, 1964], No. 1319/64. Heading B5N. [Also in Divisions C3 and C5] A polymeric material containing at least one group of the formula where A is C1 or C 1-4  straight-chain alkoxy, R<SP>1</SP> is aryl, preferably phenyl, R<SP>11</SP> is C1, aryloxy or C 1-6  straight-chain alkoxy, x + y = 2 and y = 1 or 2; when y = 2 both siloxane groups are directly attached to the P atom, is used to prepare heat-stable laminates with e.g. asbestos. The laminate may be prepared by dissolving the polymer above in dimethyl formamide, chlorobenzene or ethanol and this solution evenly dispersed over both sides of an asbestos sheet, the resulting combination being dried at 80‹ C. in an oven. The dried, impregnated sheet may be used as such, or cut into strips. A pile of these strips is placed between two sheets of polythene and compressed cold to ¢-¥ inch thickness, and subsequently cured at 300‹ C. under 1400 1b. inch<SP>2</SP> pressure. The pile of strips is coated with graphite to prevent sticking in the hot press. It is essential to release the pressure two or three times at the start of each curing procedure to allow gases to escape.
Patent GB-1052612-A (GB)
IPC: H01J61/12
Abstract: 1,052,612. Discharge lamps. PATENTTREUHAND-GESELLSCHAFT FUR ELEKTRISCHE GLUHLAMPEN m.b.H. Feb. 5. 1965 [March 3, 1964], No. 5112/65. Heading H1D. The filling of a high pressure discharge lamp having discharge-heated electrodes includes a uranium halide, e.g. uranium iodide or bromide, and may also include either several atmospheres pressure of completely vaporized mercury, together with argon as starting gas, or several atmospheres pressure of xenon; addition of one or more of the iodides of thallium, indium, sodium, and scandium is also referred to. In a filling which includes mercury, the ratio of the partial pressures of uranium to mercury is higher than 3 x 10<SP>-4</SP>. The uranium halide is preferably introduced as metallic uranium and elementary halide or mercury halide, in stoichiometric proportion. Envelope dimensions and wall loadings are given.
Patent GB-1053300-A (GB)
IPC: C09B1/28
Abstract: 1,053,300. Anthraquinone basic dyes. L'OREAL. Oct. 29, 1963 [Oct. 29, 1962: Oct. 24, 1963], No. 42691/63. Heading C4P. [Also in Division D1] The invention comprises dyes having the general formula. in which one X is -NH-Z, the other two are hydrogen in which Z is a group -ArNRR 1  in which Ar is an arylene radical, R and R 1  are alkyl (C 1 -C 4 ) groups or form together with the nitrogen atom a piperidine or morpholine ring or alternatively Z may be the group -(CH 2 ) n NRR 1  in which R and R 1  form part of the heterocyclic rings as above, n has the values 2-6. The invention also comprises the quaternary ammonium salts of the above, especially the methyl sulphate and benzyl chloride derivatives. The dyes are obtained by the reaction of a diamine of formula NH 2 -(CH 2 ) n -NRR 1  or NH 2 -Ar-NRR 1  with quinizarin, leuco quinizarin (followed by oxidation) or 1,5- or 1,8-dichloroanthraquinone followed if required by quaternization in the presence or absence of an organic solvent. Many examples of these dyes are given.
Patent GB-1058291-A (GB)
Abstract: 1,058,291. Collectors. SPERRY RAND CORPORATION. April 29, 1964 [April 29, 1963], No. 17713/64. Heading H2E. [Also in Division G1] Gyroscopic apparatus is provided with electrical brushes mounted on one member for rotation about one axis relative to electrical slip rings mounted on another member, the slip rings being mounted coaxially on a further axis parallel to the one axis, and means being provided for rotating the further axis about the said one axis with periodic reversal of the direction of rotation, so that the brushes and slip rings are maintained in relative motion, thus inhibiting undesirable effects of coulomb friction. In the two-degree of freedom directional gyro shown in Fig. 1, a rotor 13 is rotated about an axis 14 by an electric motor (not shown) within a rotor case 12. The case 12 is journalled in a gimbal 15 which is in turn journalled in a housing 11. Each of the journal bearings comprises inner, outer and intermediate concentric members with interposed ball races and the intermediate members are rotated with periodic reversal of rotation by use of bevel gears 25, 26, 27, 28, driven so that the intermediate members on each axis rotate in opposite directions to each other. Electrical connections to a power source 35 and a signal utilization device 35<SP>1</SP> are carried through the journal bearings on an axis 17 by bushes 38, 39 and slip rings 40, 42. The brushes 38 are mounted on the housing 11 and the slip rings 40 on a shaft 41. The gimbal 15 is mounted on the outer member of the journal bearing 22 and the inner member is fixed to the housing 11, the axis of the journal bearing being the axis 17. The shaft 41 is carried by the inner member 65<SP>1</SP> of a bearing 65, the outer member of which 65<SP>11</SP> is secured to the intermediate member of the journal bearing 22. The axis 45 of the bearing 65 and thus that of the slip rings 40 is parallel to and displaced from the axis .17, e.g. 0.002 inch. Thus as the intermediate member of the bearing 22 is rotated, the axis 45 orbits round the axis 17, so that a sinusoidal sliding velocity is imposed between the slip rings and brushes to reduce coulomb friction effects. The shaft 41 is rigid with a dome-shaped bridge support member 50 which is slidable in a horizontal plane, in Fig. 1, relative to the gimbal 15 but rotates with it by the provision of three keyed projections as 70 sliding in guides at 73. This allows for the orbital motion of the shaft 41 relative to the gimbal 15 but ensures that the slip rings 40 rotate with the gimbal. The member 50 carries the electrical leads 44 from the slip rings 40. The slip rings 42 are mounted in a similar manner to the slip rings 40, and pick-offs 32, 34 and a torquer 33 are provided in the assembly.
Patent GB-1063770-A (GB)
Abstract: 1,063,770. Rotary pumps and motors. CHAR-LYNN CO. Dec. 31, 1965 [June 21, 1965], No. 55479/65. Heading F1F. A rotary pump or motor of the kind comprising a stationary internally-toothed ring member 4, Fig .1, and an externally-toothed star member 18 having one less tooth, includes a shaft 66 having at its ends splined joints including balls 67 connecting it to the star member and to a valve member 28, supplying and discharging fluid to and from variable volume chambers between the ring and star members, formed integral with or fixed to an input or output shaft 30 so that the star member rotates about its own axis in one direction and orbits about an axis 24 common to the ring member 4, valve member 28 and shaft 30 in the opposite direction whilst the valve member rotates about the axis 24. The orbital movement of the star member results in a radial force which rotates about the axis 24 at the orbital speed of the star member 18. This radial force is balanced by a counterweight 56, rotatable about the axis 24 and having a slot 59 co-operable with a pin 70 forming an extension of the shaft 66 so that the counterweight is rotated with the star member with its centre of gravity diametrically opposite to that of the star member.
Patent GB-1084224-A (GB)
IPC: B66F7/04
Abstract: 1,084,224. Mobile cranes; garage lifts. J. TRANCHERO. Sept. 17, 1964 [Sept. 17, 1963], No. 37972/64. Headings B8B and B8H   A mobile crane for use in a garage comprises a telescopic jib 18 which is connected by links 14, 16 to a column 12 on a wheeled base frame 42, 44 and which is luffed by an hydraulic ram 22, 24. A vehicle-supporting carriage 34a provided with adjustable vehicle-engaging supports 40, is guided for vertical movement on the column 12 by rollers 36 and is connected to the jib 18 by links 34.
Patent GB-1225720-A (GB)
IPC: B28B21/90
Filed: 1969-05-08
Abstract: 1,225,720. Removing asbestos pipes from mandrels. SPETSIALNOE KONSTRUKTORSKOE BJURO PO OBORUDOVANIJUDLYA PROIZVODSTVA ASBESTOTSEMENTNYKH IZDELY I RULONNOKROVELNYKH MATERIALOV. 8 May, 1969, No. 23433/69. Heading F2P. Apparatus for removing an asbestos-cement pipe 7 from a mandrel 6 comprises two levers 1, 2 which are pivoted together at 3, one lever 1 being pivoted at 5 to a fixed member 4, a needle 9 being pivoted to the free end of the other lever at 10, and a spring 11 being connected between the needle 9 and the pivot 5. A roller 8 is pivoted about the axis 10 and a ram 14, pivoted to the axis 10 and a ram 14, pivoted to the member 4, has its piston-rod 17 pivoted at 18 to the lever 1. Stops 19, 20 and 12, 13 limit respectively the opening and closing movements of the two levers. In use, an initial outward movement of the rod 17, rotates the levers 1, 2 about the pivot 5, the levers 1, 2 maintaining the same spacing. When the roller 8 meets the mandrel 6 further extension of the rod 17 causes the needle 9 to penetrate, fully, into the end of the pipe, whereupon reversal of the direction of the rod 17 causes the pipe and mandrel to be withdrawn from the pipe forming apparatus, not shown, the pipe being subsequently removed from the mandrel.