baber/WOPTO huggingface dataset:
Patent NZ-311833-A (NZ)
Title: Sealing device for sealing a rotary shaft comprises a seal holder attached to a casing with a mechanical shaft seal and openings
Inventor: FORSLUND KJELL
IPC: F16J15/34
Filed: 1996-06-24
Abstract: PCT No. PCT/SE96/00821 Sec. 371 Date Dec. 30, 1997 Sec. 102(e) Date Dec. 30, 1997 PCT Filed Jun. 24, 1996 PCT Pub. No. WO97/02384 PCT Pub. Date Jan. 23, 1997Apparatus for sealing rotary shafts supported by bearings within an airtight casing and extending into a housing maintained at an overpressure is disclosed including a mechanical shaft seal for sealing the shaft as it passes into the housing, a seal mount mounted on the casing for mounting the mechanical shaft seal, the casing including an opening to provide access to the mechanical shaft seal within the casing, and a removable airtight cover for sealing the opening in the casing during operation of the apparatus.
Patent NZ-314485-A (NZ)
Title: stress-relieving livestock food containing yeast and glutathione
Inventor: FUJIMURA MOTOKI
IPC: A23K1/18
Filed: 1997-03-26
Abstract: he present invention relates to the use of a feed composition comprising: a)	glutathione-rich yeast; or b)	a mixture of glutathione and yeast for relieving stress in livestock and poultry. The yeast is selected from Torulaspora yeast,  baker's yeast and brewer's yeast, and also claimed is the method of relieving stress of livestock and poultry where an effective amount is given in the feed to the animals.
Patent NZ-329759-A (NZ)
Title: Roller hold down device for four-sided tapered cartons
Inventor: SUNDQUIST MATT
IPC: B65B43/39
Filed: 1997-09-23
Abstract: [ A carton flap hold down apparatus (25) for use in seating an open-ended sleeve-type carton (40) on a carton transport conveyor (27) is disclosed. The carton flap hold down apparatus has a plurality of aligned carton flap hold down rollers (61) disposed along a common longitudinal axis and extending in the direction of a path of travel, each support roller being supported for rotation on an elongate roller support bar (65). A mounting block (67) is fastened on a framework of the carton transport conveyor with respect to a carton flap score rail (31) thereof, the mounting block being spaced from the roller support bar, and an elongate intermediate member (66) is fastened to one end of the mounting block, and fastened at the other of its ends to the roller support bar. The rollers are inclined toward the mounting block in the direction of the path of travel at an angle of 5° for holding, and pulling, the bottom flaps of the carton downwardly against the carton flap score rail to ensure that the carton remains fully seated on the carton transport conveyor as articles are transferred therein from an article selector device. The intermediate member is constructed and arranged to urge the roller support bar toward the carton flap score rail so that each one of the rollers is yieldably engaged on the carton flap score rail for slidably holding the bottom flap of the cartons thereon as the cartons advance along the path of travel.
Patent NZ-331705-A (NZ)
Title: Immediate release ph-independent solid dosage form of cisapride
Inventor: GILIS PAUL MARIE VICTOR
IPC: A61K31/445
Filed: 1997-03-20
Abstract: The present invention concerns oral dosage forms of some particular salts of cisapride, more particularly cisapride-(L)-tartrate, cisapride-(D)-tartrate, cisapride-sulfate, or cisapride citrate, which avoid drugfood interaction and which allow comedication of agents that increase the pH of the stomach. The invention particularly relates to solid oral dosage forms suitable for rapid dissolution. The present invention also concerns tablets which can be prepared via direct compression.
Patent NZ-334147-A (NZ)
Title: Immortalised cell lines derived from chicken embryonic fibroblasts and having a population doubling rate of 0.6 to 1.2 population doublings per day
Inventor: FOSTER DOUGLAS N
IPC: C12N/
Filed: 1997-08-13
Abstract: A spontaneously immortalised cell line that supports virus replication, derived from primary chicken embryonic fibroblasts, wherein the cell line is capable of growth in culture at a population doubling rate of between 0.6 and 1.2 population doublings per day. The virus grown in the cell line disclosed is a retrovirus, a herpesvirus or a Marek's disease virus.
Patent NZ-336269-A (NZ)
Title: Solid ionic complex of LHRH analogue containing 5-20 amino acids with a weight ratio of carrier:analogue 0.5:1 to 0.1:1 suitable for administration with in a syringe
Inventor: GEFTER MALCOLM L
IPC: A61K38/095
Filed: 1997-12-11
Abstract: Sustained delivery formulations comprising a water-insoluble complex of a peptide and a carrier macromolecule are described. The formulations allow for loading of high concentrations of peptide in a small volume and for delivery of a pharmaceutically active peptide for prolonged periods, e.g., one month, after administration of the complex. The complexes can be milled or crushed to a fine powder. In powdered form, the complexes form stable aqueous suspensions and dispersions, suitable for injection. In a preferred embodiment, the peptide of the complex is an LHRH analogue, preferably an LHRH antagonist, and the carrier macromolecule is an anionic polymer, preferably carboxymethylcellulose. Methods of making the complexes, and methods of using LHRH-analogue-containing complexes to treat conditions treatable with an LHRH analogue, are also described.
Patent NZ-336576-A (NZ)
Title: Method of killing breast cancer cells with a combination of two immunotoxins
IPC: A61K39/40
Filed: 1999-07-05
Abstract: This method for killing unwanted target cells in a cell population comprising nucleated cells harvested from peripheral blood, or CD-34+ or similar early progenitor cells selected from the above nucleated cells or from bone marrow aspirates by selectively killing the malignant cells comprises: Exposure of the cell population to two or more immunotoxins where each immunotoxin is composed of a conjugate between an antibody and a toxin.  One antibody targets an epitope of the antigen EGP2 expressed by the gene GA733-2 and the other antibody targets an epitope of the antigen expressed by the genes MUC1, MUC2 or MUC3s,  and the toxin is Pseudomonas exotoxin A
Patent NZ-336825-A (NZ)
Title: Aqueous medicament preparations containing a complexing agent for the production of propellent gas-free aerosols
Inventor: FREUND BERNHARD
IPC: A61K47/18
Filed: 1997-12-16
Abstract: An aqueous pharmaceutical preparation containing an active ingredient selected from betamimetics, anticholinergics, antiallergics and/or antihistamines, a complexing agent such as EDTA and up to but excluding 70% (by volume) of ethanol is used to produce a propellant-free aerosol for inhalation.
Patent NZ-501957-A (NZ)
Title: Health supplement containing a bulk forming material, cholesterol reducer and a fatty acid promoter
Inventor: TOPPING DAVID
IPC: A61K31/718
Filed: 1998-06-30
Abstract: A composition comprises a bulk forming component, a cholesterol reducing component and a fatty acid wherein one of these component is a starch, the presence of the starch countering any expected deleterious effects of bulk formation or fatty acid depletion, such that the level of butyric acid in the colon of the subject consuming the composition is maintained above expected levels.
Patent NZ-502580-A (NZ)
Title: 4-amino-phenylalanine compounds which inhibit leukocyte adhesion mediated by VLA-4
Inventor: THORSETT EUGENE D
IPC: A61P25/28
Filed: 1998-07-30
Abstract: The compounds of formula I bind VLA-4 and inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. The compounds may be used in the treatment of inflammatory diseases such as asthma, Alzheimer's disease, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, tissue transplantation, tumour metastasis, multiple sclerosis, rheumatoid arthritis, tissue transplantation, tumor mestasis, meningitis, encephalitis, stroke, nephritis, retinitis, atopic dermatitis, psoriasis, myocardial ischemia and acute leukocyte-mediated lung injury. In formula I;  R1 is selected from the group consisting of optionally substituted alkyl, optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted heterocyclic and optionally substituted heteroaryl; R2 is selected from hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted heterocyclic, optionally substituted aryl, optionally substituted heteroaryl; or R1 and R2 together with the N atom and the SO2 group form a optionally substituted heterocyclic; R3 is hydrogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted heterocyclic and optionally substituted heteroaryl; or when R2 does not form a heterocyclic group with R1, R2 and R3 together with the N atom can form an optionally substituted heterocyclic group; R5 is (CH2)xArR5',  where R5' is selected from NR12C(Z)NR8R8' and NR12C(Z)R13, wherein R12 is selected from hydrogen, alkyl and aryl; R8 and R8' are independently selected from hydrogen, optionally substituted alkyl, aryl, cycloalkyl, heterocyclic or heteroaryl, provided that when Z is O, at least one of R8 and R8' is substituted alkyl, optionally substituted cycloalkyl, saturated heterocyclic other than morpholino and thiomorpholino, or substituted heterocyclic, and R8 and R8' can be joined to form a saturated substituted heterocycle or a saturated/unsaturated heterocycle having an amino group substituted with an alkoxycarbonyl substituent; and further provided that when Z is S, at least one of R8 and R8' is a group other than optionally substituted aryl or heteroaryl; and R13 is saturated heterocycle or substituted heterocycle; Ar is optionally substituted aryl or heteroaryl; and x is 1 to 4; and Q is C(X)NR7, where R7 is hydrogen or alkyl; and X is O or S.
Patent NZ-507635-A (NZ)
Title: Modifying the atmosphere in a refrigerated container using an apparatus to withdraw gaseous by-products and filter the by-products prior to its return
Inventor: LEMCOFF NORBERTO
IPC: A23L3/3445
Filed: 2000-10-18
Abstract: An apparatus and method for controlling the composition of the atmosphere within a refrigerated container (13) during the storage and/or transportation of perishable and/or respiring produce in which, a portion of the container atmosphere is withdrawn and pressurised and passed over a number of absorbents (1) to remove carbon dioxide and ethylene (and other evolved hydrocarbons).  The adsorptive materials are regenerated with ambient air.
Patent NZ-509817-A (NZ)
Title: Pill dispenser has a ring shaped pill package and a push out mechanism to allow stepwise positioning of the pill package and dispensing of pills
Inventor: VAN DULLEMEN MARLIES
IPC: A61J7/04
Filed: 1999-08-16
Abstract: An apparatus for dispensing pills comprises at least a ring-shaped blister-pack (2), in which cavities (3) containing pills (P) are distributed, such that the openings of the cavities (3) therein are directed outwardly, as well as a flat pocket dispenser. It has a first part (5) for receiving the pack (2) in a ring shape, and has a second part (6) fitting onto the first part (5) and encasing the blister-pack (2) together with the opening (7) with which a pill (P) to be dispensed can be aligned. A push-out means (8) can be positioned in line with the respective pills (P) of the blister pack (2) and is operable for pushing out the pill (P) to be dispensed through the passage opening (7). There are provided means (10, 12-15, 34-36) for stepwise rotatably positioning the blister pack (2) relative to the part including the push out means (8). The blister-pack (2) itself and the part containing the push out means (8) comprise means for stepwise positioning the blister pack.
Patent NZ-511785-A (NZ)
Title: Preparations of aqueous-based cleaning agents which form vesicles and which contain active agents, method for their production and their utilisation
Inventor: PASPALEEVA-KUHN VALENTINA
IPC: C11D1/83
Filed: 1999-11-09
Abstract: An aqueous based cleaning preparation useful in washing gels, shower preparations, foam baths and shampoos comprises 1 to 60% by weight of one or more surfactants chosen from anionic/nonionic and/or amphoteric and/or cationic surfactants with the exception of esterquats and 0.001-15% by weight of a mixture of a sterol and an ethoxylated sterol.
Patent NZ-512055-A (NZ)
Title: Modified antibodies and antibody fragments with increased duration of activity
Inventor: HEAVNER GEORGE A
IPC: C07K16/28
Filed: 1999-11-02
Abstract: Disclosed are modified antibodies or modified antigen- binding fragments that bind to one or more human integrin receptors selected from the group consisting of GPIIb/IIIa, áãâ3 and Mac-1, and comprise one to about six organic moieties which are covalently bonded to specific sites on the antibodies. The organic moieties can each independently be a hydrophilic polymeric group, a fatty acid group, a fatty acid ester group, a lipid group or a phospholipid group. Also disclosed is a method of treating a human with a disease or disorder in which cells expressing GPIIb/IIIa, áãâ3and/or Mac-1 play a pathophysiological role. The method comprises administering an effective amount of one or more of the antibodies to a human in need thereof.
Patent NZ-513818-A (NZ)
Title: Thermoplastic Tube
Inventor: VAN LENTHE ARJAN DIRK
IPC: B29C48/90
Filed: 2000-03-03
Abstract: A method for producing a tube section from thermoplastic material, in which a tube section is extruded by means of an extruder which is provided with an extruder die having an inner core, which inner core defines an axial hollow space in the tube section, the tube section coming out of the extruder die downstream of the extruder die being internally cooled by means of an internal cooling member and externally cooled by means of an external cooling device. Immediately after the tube section leaves the extruder die, the internal cooling member brings about internal cooling of the tube. The external cooling device is positioned downstream of the internal cooling member, so that the external cooling of the tube section is brought about after the internal cooling.
Patent NZ-514195-A (NZ)
Title: Amide derivatives
Inventor: BROWN DEARG SUTHERLAND
IPC: C07D239/70
Filed: 2000-03-13
Abstract: The application discloses an amide derivatives of Formula Ia (see below) wherein; * X is - NHCO- or -CONH-; * m is 0-3; * R1 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; * n is 0-2; * R2 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino and carboxy; * R3 is hydrogen, halogeno, (1-6C)alkyl or (1-6C)alkoxy; * q is 0-4; * Q is a group such as aryl, aryloxy, aryl-(1-6C)alkoxy, arylamino and (1-6C)alkyl-arylamino; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; The process for their preparation, compositions containing amide derivatives and their use in pharmaceuticals for the treatment of diseases or medical conditions mediated by cytokines are all claimed.
Patent NZ-518542-A (NZ)
Title: Triphenylalkene derivatives and their use as selective estrogen receptor modulators
Inventor: SODERVALL MARJA-LIISA
IPC: A61K31/09
Filed: 2000-11-01
Abstract: Selective estrogen receptor modulator compounds of general formula (I), wherein R1 and R2, which are the same or different are a) H, halogen, OCH3, OH; or b) substituent of formula (II), where X is O, NH or S; and n is an integer from 1 to 4; and R4 and R5, which are the same or different, are a 1 to 4 carbon alkyl, H, -CH2CºCH or -CH2CH2OH; or R4 and R5 form an N-containing five- or six-membered ring or heteroaromatic ring; or c) -Y-(CH2)nCH2-O-R6, where Y is O, NH or S and n is an integer from 1 to 4; and R6 is H, -CH2CH2OH, or -CH2CH2Cl; or d) 2,3-dihydroxypropoxy, 2-methylsulfamylethoxy, 2-chloroethoxy, 1-ethyl-2-hydroxyethoxy, 2,2-diethyl-2-hydroxyethoxy or carboxymethoxy; and R3 is H, halogen, OH or -OCH3; and their non-toxic pharmaceutically acceptable salts and esters and mixtures thereof, which compounds exhibit pharmacological properties are disclosed.
Patent NZ-524659-A (NZ)
Title: Lead-acid batteries and positive plate and alloys therefor
Inventor: LARSEN STEVEN R
IPC: H01M4/14
Filed: 2001-08-09
Abstract: A lead-acid battery comprises a container, at least one positive plate and a negative plate disposed within the container; a separator disposed within the container and separating the positive and negative plates and an electrolyte. The positive plate comprises a grid supporting structure having a layer of active material pasted thereto. The grid supporting structure comprises a lead-based alloy consisting essentially of lead, from 0.02% to 0.06% calcium, from 2% to 2.5% tin, and from 0.01% to 0.02% silver. The percentages are based upon the total weight of the lead-based alloy.
Patent NZ-525573-A (NZ)
Title: LFA-1 antagonist compounds
Inventor: BURDICK DANIEL J
IPC: A61K31/198
Filed: 2001-11-26
Abstract: A compound of formula (I) is described wherein Cy is a non-aromatic carbocycle or heterocycle; X is a divalent hydrocarbon chain; Y is a carbocycle or heterocycle; L is a divalent hydrocarbon chain optionally having one or more carbon atoms replaced with N, O, S, SO and SO2; or three carbon atoms of the divalent hydrocarbon are replaced with an amino acid residue. R1 is disclosed to be H, OH, amino, O-carbocycle or alkoxy optionally substituted with amino, a carbocycle or heterocycle; R2-5 are independently H, hydroxyl, mercapto, halogen, cyano, amino, amindine, guanidine, nitro or alkoxy; or R3 and R4 together form a fused carbocycle or heterocycle; R6 is H or a hydrocarbon chain optionally substituted with a carbocycle or a heterocycle. Included is a proviso explaining that when Y is phenyl, R2, R4 and R5 are H, R3 is Cl and R1 is OH, then X is not cyclohexyl.  The compound is disclosed to be used in pharmaceutical compositions for the treatment of a disease or condition mediated by LFA-1 in a mammal which includes arthritis, psoriasis, organ transplant rejection and asthma.
Patent NZ-527361-A (NZ)
Title: Rigid hull boat with foam and air stabilisers
Inventor: HANSEN WILLIAM
IPC: B63B7/08
Filed: 2002-01-14
Abstract: A foam and air stablilised watercraft comprising: (a) a rigid hull with a bow, stern, bottom and two sides, (b) foam and air stabilisers mounted on the exterior of the hull and extending along at least some portion of each of the sides from the stern to the bow, the foam and air stabilisers extending outward from the sides. The stabilisers further comprising one or more water and air-tight bladders partially filled with pliable closed cell foam, wherein the bladders further comprise one or more internal panels holding the foam in place within the water and air-tight bladder.
Patent NZ-529852-A (NZ)
Title: Aluminium electrowinning cells having a drained cathode bottom and an aluminium collection reservoir
Inventor: DE NORA VITTORIO
IPC: C25C3/08
Filed: 2002-05-28
Abstract: A cell for the electrowinning of aluminium has a cell bottom that comprises: a series of carbon cathode blocks (25) having an aluminium-wettable upper surface (22); aluminium-wettable openly porous plates (21) which are placed on the upper surfaces of the carbon cathode blocks and which are filled with molten aluminium to form an aluminium-wetted drained active cathode surface (20) above the upper surfaces of the carbon cathode blocks ; and a recess (35) formed in a reservoir body (30) and located at a level below the upper surfaces of the carbon cathode blocks and which during use collects molten aluminium (60) drained from the aluminium-wettable drained active cathode surface. The openly porous plates on the upper surfaces of the carbon cathode blocks extend over at least part of the recess such that part of the aluminium-wetted drained active cathode surface is located over the aluminium collection recess.
Patent NZ-531818-A (NZ)
Title: Recombinant anti-osteopontin antibody and use in the treatment of autoimmune diseases such as rheumatoid arthritis and osteoarthritis
Inventor: UEDE TOSHIMITSU
IPC: C07K16/24
Filed: 2002-09-25
Abstract: Described is a recombinant antibody in which at least the constant regions in the heavy chain and the light chain have been converted into human-origin regions and that inhibits the binding of an integrin recognising the RGD sequence to osteopontin and inhibits the binding of an integrin recognising the SVVYGLR sequence or a sequence corresponding thereto to osteopontin. This antibody is useful as a remedy for autoimmune diseases and a remedy for rheumatism or rheumatoid arthritis. This osteopontin antibody is also useful in a diagnostic for rheumatism and a method of diagnosing rheumatism.
Patent NZ-538166-A (NZ)
Title: Heterocyclic aromatic compounds useful as growth hormone secretagogues
Inventor: YU GUIXUE
IPC: A61K31/4439
Filed: 2003-09-02
Abstract: Disclosed are compounds of formula I wherein the substituents are as defined in the specification. Also disclosed is the use of compounds of formula I in the manufacture of medicaments for increasing levels of endogenous growth hormone in a patient in need thereof, for example for the treating or delaying HIV wasting syndrome, muscular atrophy, lipodistrophy, long term critical illness, osteoporosis, sarcopenia, frailty or ARFD in the elderly, obesity, renal disease, anorexia, sleep disorders, depression, Syndrome X, diabetes, congestive heart failure, cardiac myopathy, cardiac dysfunction associated with valvular disease and cachexia
Patent NZ-538674-A (NZ)
Title: A system and a method for observing and predicting physiological state of an animal
Inventor: FRIGGENS NIC C
IPC: G01N33/04
Filed: 2003-08-08
Abstract: A system for observing and predicting a physiological state of an animal comprises: a computer comprising a processor and being operatively connected to a database, at least one sample providing device for repetitively providing at least one sample of a body fluid of the animal, an analysis apparatus for analyzing the at least one sample, so as to obtain at least one sample value of at least one parameter of the body fluid, a data interface for repetitively entering the sample value of the at least one parameter in the database, wherein the database is adapted to store multiple database entries representing the sample value of the at least one parameter at various points in time, and wherein the processor is programmed to perform at least one mathematical analysis of the at least one sample value, and selecting, on the basis of the at least one mathematical analysis, the point in time for providing a subsequent sample and performing a subsequent analysis of the subsequent sample for at least one of the parameters.