baber/WOPTO huggingface dataset:
Patent CA-2311928-A1 (CA)
Title: Inhibitors of farnesyl-protein transferase
Inventor: CICCARONE TERRENCE M
IPC: C07D401/06
Filed: 1998-11-30
Abstract: The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogne protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
Patent CA-2312749-A1 (CA)
Title: Pdgf receptor kinase inhibitory compounds and compositions, method for synthesis of same and use of same for treatment of proliferate disorders
Inventor: LEVITZKI ALEXANDER
IPC: C07D215/20
Filed: 1998-11-30
Abstract: PDGF receptor kinase inhibitory compounds of the quinoxaline family, methods for their synthesis and containment in slow release pharmaceutical preparations, and their use for treatment of proliferative malignant and nonmalignant diseases or disorders by local or systemic application. A compound according to the invention includes a tyrphostin of general formula (I), wherein R1 and R2 are each independently selected from the group consisting of alkyl, alkoxy, halogen, nitro and amine and Ar is selected from the group consisting of phenyl, ferrocene, thiophene, furane, pyrrole, indole, thiazole, imidazole and pyridine.
Patent CA-2315843-A1 (CA)
Inventor: FABIANO VINCENT L
IPC: A61P13/00
Filed: 1998-12-29
Abstract: Cette invention a trait à une méthode visant à traiter l'incontinence urinaire, notamment l'incontinence résultant d'une instabilité du détrusor de la vessie, laquelle méthode fait appel à la procyclidine-(S) enrichie par énantiomères. Cette méthode consiste à administrer une quantité efficace du point de vue thérapeutique de procyclidine-(S) enrichie par énantiomères ou d'un sel de celle-ci, acceptable du point de vue pharmaceutique, quasiment exempt d'énantiomère de procyclidine-(R). L'invention porte également, d'une part, sur des compositions pharmaceutiques permettant de traiter l'incontinence urinaire et renfermant de la procyclidine-(S) enrichie par énantiomères ou un sel de celle-ci, acceptable du point de vue pharmaceutique et, d'autre part, sur un excipient approprié.
Patent CA-2317252-A1 (CA)
Title: Portable environmental containment system
Inventor: STARHEIM SCOT A
IPC: E21B21/01
Filed: 2000-08-30
Abstract: A temporary berm or bin system, easily transported, erected without tools, and easily dismantled. A set of panels or planks is joined with sliding clips to form a bin having vertical or near vertical sides. The bin is lined with an impervious sheet of geocloth to form a containment bean for use in controlling the dispersal of hazardous material spilled from storage or work facilities. Spring loaded clamps hold the geocloth securely to the uppermost plank without nailing, sewing, or other labor consuming and/or tear prone methods. The bean is particularly suited to protect oil well drilling sites in environmentally sensitive environments such as arctic tundra. No excavation or other disturbance of the soil is required to erect the protective bean. The bean is secured to the ground by spiking through triangular support gussets. In the arctic, securing may be accomplished by freezing ice or mud as an "ice mortar" over the gusset feet and along the lower edge of the planking. The berm system may be transported by ordinary truck, specially adapted transport/laying truck, or on a portable drilling platform.
Patent CA-2318515-A1 (CA)
Title: Plant packaging method and product
Inventor: WEDER DONALD E
IPC: B65B11/00
Filed: 1995-03-30
Abstract: A plant package assembly, comprising a pot containing a floral grouping and a flexible sleeve having detaching elements at preselected areas, the sleeve further comprising a bonding material which connects the sleeve to the pot when the pot is positioned within the sleeve, the sleeve being positioned about the pot and a lower portion of the sleeve closely surrounding and encompassing the pot, an upper portion of the sleeve extending upwardly from the pot and substantially surrounding and encompassing the floral grouping contained within the pot, at least a portion of the sleeve being removable via the detaching elements, leaving a portion of the sleeve which is a decorative plant cover.
Patent CA-2319213-A1 (CA)
Title: Nucleic acids and proteins of the mycoplasma hyopneumoniae mhp3 gene and uses thereof
Inventor: MADURA REBECCA ANNE
IPC: A61P31/04
Filed: 2000-09-27
Abstract: The present invention relates to mhp3 nucleic acids and proteins encoded by the foregoing. The present invention further relates to novel apoprotein antigens encoded by mhp3 for use in vaccines to prevent and treat diseases caused by infection with Mycoplasma hyopneumoniae. The invention further relates to methods for the recombinant production of such antigens.
Patent CA-2322275-A1 (CA)
Inventor: ANDERSON COLLIN D
IPC: B24B7/19
Filed: 1999-02-26
Abstract: A method and apparatus for repairing optical discs (30), wherein the apparatus includes an improved buffing wheel (10) capable of applying a uniform buffing action across the readable surface (38) of an optical disc (30), and wherein the method includes the step of mechanically buffing the damaged area (40) of a disc (30) with an abrasive means (22) and thereafter buffing the buffed area (50) with a non-abrasive means (52) to remove fine scratches (50) caused by the abrasive means (22).
Patent CA-2329126-A1 (CA)
Inventor: WATT PAUL M
IPC: A61M15/00
Filed: 1999-04-20
Abstract: The present invention provides an incentive inhaler device (2) comprising (i) an inhalation device comprising a mask or mouthpiece (6) and a connector (4) that is linkable to a drug delivery device or other device for the delivery of an aerosol, powder or gas; and (ii) one or more external visible and/or audible inhalation/exhalation-driven incentive toys (12, 14), wherein each of said toys is separated from one or more components of said inhalation device (i) by one or more valves, filters or baffles (18, 24) to ensure directional flow of inhaled/exhaled air which drives said toys and/or filtration of microbes, condensation or particles from exhaled air.  The incentive inhaler device (2) of the present invention provides a stimulus to a child or infant to inhale a pharmacological or medicinal compound or anaesthetic compound and promotes correct breathing technique. The present invention further provides components and kits for use with the subject incentive inhaler device and methods of stimulating to a child or infant to inhale a pharmacological or medicinal compound or anaesthetic compound.
Patent CA-2330108-A1 (CA)
Title: Novel substituted aryl hydroxamic acids as metalloproteinase inhibitors
Inventor: VOSS MATTHEW E
IPC: A61K31/541
Filed: 1999-05-12
Abstract: The present application describes novel substituted aryl hydroxamic acids of formula (I) or pharmaceutically acceptable salt forms thereof, wherein ring A is a 5-8 membered ring containing from 0-1 additional heteroatoms selected from N, O, and S, which are useful as metalloproteinase inhibitors and inhibitors of TNF.
Patent CA-2330146-A1 (CA)
Title: Take-up reel, veneer reeling apparatus, tape feeding unit for veneer roll, and veneer roll unwinding apparatus and a production method for laminated wood
Inventor: NAKAGAWA SHINICHI
IPC: B65H75/04
Filed: 2000-01-07
Abstract: A take-up reel has a diameter equal to or more than 85 times a thickness of a veneer sheet wound thereon and equal to or more than 300 mm so as to be of a curvature of the take-up reel to reduce cracking in parallel to fiber orientations that occurs in winding a veneer sheet after drying on a winding surface of the take-up reel. A veneer reeling apparatus comprises: a take-up reel disposed in a veneer sheet reeling position in a rotatable manner; a drive roller disposed on the lower surface of the take-up reel, transmitting a driving force with a variable speed; a veneer dryer disposed upstream from the veneer sheet reeling position; a conveyor provided between the terminal end of the veneer dryer and the drive roller in the veneer sheet reeling position; and a plurality of thread feeding mechanisms disposed at arbitrary spatial intervals along a length direction of the take-up reel for a veneer sheet, wherein a continuous dried veneer sheet or dried veneer sheets whose sizes are of a constant length or of a length at random are wound on the take-up reel to form a veneer roll with threads as guide by a frictional force of the drive roller. Further, pairs of two overlapping veneer sheets or sets of a pair of two overlapping veneer sheets and a single veneer sheet can be wound on the take-up reel in a composite form.
Patent CA-2331454-A1 (CA)
Title: Process for producing spherical oxide particles
Inventor: MATSUMOTO NOBUHITO
IPC: B01J35/08
Filed: 1999-05-11
Abstract: The invention pertains to a process for preparing spherical oxide particles comprising the steps of shaping a starting material comprising an oxide hydrate into particles of substantially constant length by leading the material to a set of two rolls rotating towards each other followed by leading the material to a roll equipped with grooves to form rod-type shapes, cutting the rod-type shapes into particles of substantially constant length, converting the thus formed particles into spheres, and heating the particles to convert the oxide hydrate into an oxide. The process results in particles in which there is substantially no difference in density between the core portion and the shell portion of the particles, which results in a high abrasion resistance. The particles prepared by the claimed process are particularly suitable for the preparation of hydroprocessing catalysts, more in particular for the preparation of hydroprocessing catalysts suitable for the hydroprocessing of heavy hydrocarbon feeds.
Patent CA-2332602-A1 (CA)
Title: Systeme de regulation d'ecoulement d'eau
Inventor: PRATT CHRISTOPHER JOHN
IPC: A01G7/00
Filed: 1999-05-17
Abstract: L'invention concerne un système de pavage permettant de réguler le drainage et/ou l'écoulement d'eau sur une pente, qui comporte une couche perméable constituant une surface (12) supérieure, au moins une couche de substrat de support située sous celle-ci et qui est perméable aux liquides, une couche (16) de confinement contenant ladite couche (20) de substrat et servant à limiter un ruissellement d'eau provenant de ladite couche de substrat de support dans le sol environnant; et un moyen (50, 60) de déversoir servant à réguler l'écoulement d'eau sur la pente.
Patent CA-2333520-A1 (CA)
Inventor: BLOCK ROLF
IPC: H04B3/46
Filed: 1999-05-03
Abstract: A first signal (s1) modulated with a first sound signal (ts1) having a first frequency (f1) and a second signal (s2) modulated with a second sound signal (ts2) having a second, higher frequency (f2) is injected into the coaxial cable (K). A defective shielding (S(d)) in an area (B) is indicated by means of acoustic reproduction of the first sound signal (ts1) when the first signal (s1) is received in a receiver (E) and the position (P) of the defective shielding (S(d)) is indicated by means of acoustic reproduction of the second sound signal (ts2) when the second signal (s2) is received.
Patent CA-2336019-A1 (CA)
Inventor: LAVON GARY DEAN
IPC: A61F13/534
Filed: 1999-06-29
Abstract: The present invention is a liquid transport member with significantly improved liquid handling capability, which has at least one bulk or inner region with a high average permeability, completely circumscribed by a wall region. The wall region further comprises at least one port region with a lower permeability than the inner region, and with a ratio of its permeability to its thickness of at least 10 -7 m.
Patent CA-2336908-A1 (CA)
Inventor: CUNNINGHAM TIMOTHY J
IPC: G01F1/84
Filed: 1999-06-23
Abstract: Ce détecteur de paramètres de fonctionnement (5) pour système de traitement de substances (1) comporte un conduit (103A-103B) conçu pour contenir des substances provenant dudit système de traitement. Plusieurs transducteurs de mouvement (105A-105D) produisent des signaux de mouvement représentatifs d'un mouvement au niveau d'un certain nombre de points du conduit. Un estimateur de paramètres de fonctionnement surestimés (30), qui réagit aux données de ces transducteurs de mouvement, est conçu pour recevoir les signaux de mouvement. Cet estimateur de paramètres de fonctionnement surestimés, qui décompose le mouvement du conduit en mouvement pouvant être attribué à chaque force d'un nombre prédéterminé de forces, estime un paramètre de fonctionnement associé à la substance se trouvant dans le conduit conformément au mouvement décomposé. Le nombre de points dans le conduit dépassant le nombre de forces, les signaux de mouvement fournissent un jeu d'information surdéterminées aux fins de la décomposition du mouvement du conduit en mouvement pouvant être attribué au nombre de forces prédéterminées.
Patent CA-2338138-A1 (CA)
Title: A method for production of a transgenic animal, and a transgenic animal produced by the method
Inventor: TAMURA MASARU
IPC: A01K67/027
Filed: 2001-02-23
Abstract: A novel and efficient method for production of a transgenic animal is developed. This invention provides a method for production of a novel transgenic animal comprising the steps of introducing a foreign gene into testis of an animal, selecting transfected spermatocytes, spermatids or spermatozoa in which the foreign gene was introduced using a fluorescence marker gene as an indicator and fertilizing an unfertilized oocyte or ovum with the transfected spermatocyte, spermatid or spermatozoa.
Patent CA-2338266-A1 (CA)
Inventor: TAKAMIZAWA YUICHIRO
IPC: G10L25/93
Filed: 2001-02-27
Abstract: A coded voice signal format converting apparatus is provided which is capable of converting a signal format of a coded voice signal by computations in reduced amounts. In the coded voice signal format converting apparatus, in a second coding device is employed a quantizing accuracy information converting section to which a first quantizing accuracy information output from a quantizing accuracy information decoding section in a first decoding device is input. Second mapping signal is quantized by a mapped signal coding section to produce a coded voice signal and the first quantizing accuracy information is converted so that it can be used by mapped signal coding section to determine a second quantizing accuracy information.
Patent CA-2341647-A1 (CA)
Title: A protection device for controlling the motion of a pneumatic actuator
Inventor: DAHLBERG URBAN
IPC: F15B11/024
Filed: 1999-09-03
Abstract: A protection device for controlling the motion of a pneumatic actuator (3), comprising at least one elongated cylinder (6) provided with a piston (4), dividing the cylinder (6) into a first chamber (5a) and a second chamber (5b), an actuating pressure supply line (14) connectable to at least one of said first and second chambers (5a, 5b), a control means (22) for controlling the motion of the piston (4) relatively to the cylinder (6), and a sensor means (23, 30) adapted to sense a piston feature related to the piston motion and being co-operating with the control means (22). According to the invention, said control means (22) limits the motion of said piston (4) as soon as signalling from said sensor means (22, 30) indicates that an excessive value of said piston motion has been established.
Patent CA-2342205-A1 (CA)
Inventor: THOMSON JAMES A
IPC: A61K35/12
Filed: 1999-05-05
Abstract: L'invention se rapporte à des procédés de production de cellules souches embryonnaires (ES) de primates qui sont appariées par LMH à un sujet donneur spécifique. Selon un des aspects de l'invention, on effectue une transplantation de noyaux cellulaires d'un primate donneur sur un ovocyte de primate énucléé. La culture du produit de transfert nucléaire résultant jusqu'à l'étape des blastocystes et l'isolement subséquent des cellules ES de primate à partir de la masse cellulaire interne est conçue pour permettre la production de cellules ES qui sont génétiquement identiques, pour tous les gènes nucléaires, au donneur du noyau d'origine. Des cellules différenciées dérivées de ces cellules ES de primates ont moins tendance à être rejetées par le système immunitaire du donneur lorsqu'elles sont utilisées à des fins thérapeutiques du type transplantation.
Patent CA-2342542-A1 (CA)
Inventor: UMENO KEN
IPC: H04B1/707
Filed: 2001-03-30
Abstract: A filter unit for filtering with a prescribed real impulse constant and a filtering method are provided. A computer-readable data recording medium recorded with a program that enables a computer, Digital Signal Processor (DSP), or a Field Programmable Gate Array (FPGA) to function as a filter unit for filtering with a prescribed real impulse constant is also provided.
Patent CA-2343295-A1 (CA)
Inventor: IDEKER RAYMOND E
IPC: A61N1/368
Filed: 1999-09-15
Abstract: An implantable system for detecting electrical activity from a patient's hea rt comprises a first sensing electrode configured for positioning through the coronary sinus ostium and within a vein on the left surface of the left ventricle of the heart for sensing electrical activity from the heart, and a  detector operatively associated with the first sensing electrode for determining (e.g. diagnosing or prognosing) a medical condition of the heart  with the sensed electrical activity. Typically the system further comprises a second sensing electrode configured for positioning in the right ventricle o f the heart, where the detector is operatively associated with both the first sensing electrode and the second sensing electrode. The second sensing electrode may be positioned in other locations as well, such as also within a vein on the left surface of the left ventricle of the heart (although spaced  apart from the first sensing electrode), in the right atrium, in the the superior vena cava, etc. Finally, a third sensing electrode may also be included, with the third electrode positioned in any of the foregoing locations (again, spaced apart from the first and second electrodes), with t he detector operatively associated with all of the first, second, and third sensing electrodes. Determination ofa medical condition may be carried out b y any suitable means, such as by detecting ectopic beats (that is, premature beats or delayed beats) in the heart. The method is particularly useful for identifying the chamber of ectopic beat origin.
Patent CA-2345357-A1 (CA)
Inventor: HILL RAYMOND GEORGE
IPC: A61P9/10
Filed: 1999-09-22
Abstract: Composé représenté par la formule I: (I) dans laquelle: R?1¿ représente naphtyle ou benzothiènyle non substitué ou substitué, dans trois positions maximum pouvant être substituées, indépendamment par alkyle C¿1?-C¿6?, halogène, alkoxy C¿1?-C¿6?, CF¿3?, OCF¿3?, NO¿2?, CN, méthylènedioxy ou éthylènedioxy; R?2¿ représente hydrogène, alkyle C¿1?-C¿8?,(CH¿2?)¿t?-aryle, aryle étant sélectionné dans phényle, biphényle et naphtyle,(CH¿2?)¿t?-hétéroaryle, hétéroaryle étant sélectionné dans tétrazolyle, oxadiazolyle, thiadiazolyle, triazolyle et pyrazinyle,(CH¿2?)¿q?C(O)OR?6¿,(CH¿2?)¿q?OR?6¿,(CH¿2?)¿q?OC(O)R?6¿,(CH¿2?)¿q?C(O)R?6¿,(CH¿2?)¿q?C(O)(CH¿2?)aryle,(CH¿2?)¿q?N(R?6¿)C(O)R?6¿,(CH¿2?)¿q?C(O)N(R?6¿)¿2?,(CH¿2?)¿q?N(R?6¿)SO¿2?R?6¿,(CH¿2?)¿q?N(R?6¿)C(O)N(R?6¿)¿2?,(CH¿2?)¿q?OC(O)N(R?6¿)¿2?,(CH¿2?)¿q?N(R?6¿)C(O)OR?6¿,(CH¿2?)¿q?N(R?6¿)SO¿2?N(R?6¿)¿2? et (CH¿2?)¿q?S(O)¿m?R?6¿; R?3¿ représente NH¿2?; R¿4? représente hydrogène, alkyle C¿1?-C¿6?, alkoxy C¿1?-C¿6?, halogène, OCF¿3? ou CF¿3?; R?5¿ représente hydrogène, alkyle C¿1?-C¿6?, alkoxy C¿1?-C¿6?, halogène, OCF¿3? ou CF¿3?; R?6¿ représente hydrogène, alkyle C¿1?-C¿8? ou cycloalkyle C¿3?-C¿7? et, quand deux groupes R?6¿ sont présents et représentent alkyle C¿1?-C¿8?, ils peuvent éventuellement, avec l'atome auquel ils sont fixés, former un noyau C¿3?-C¿8?; Q représente (CH¿2?)¿x?-C(R?7¿)(R?7a¿)-(CH¿2?)¿y?- ou (CH¿2?)¿x?-V-(CH¿2?)¿y?-; R?7¿ et R?7a¿ sont sélectionnés indépendamment dans hydrogène, CF¿3?, halogène, alkyle C¿1?-C¿6? et alkoxy C¿1?-C¿6?; V représente un noyau C¿3?-C¿8? non aromatique cyclique ou bicyclique ou un noyau aromatique benzène ou naphtalène, ledit noyau étant non substitué ou substitué dans trois positions maximum pouvant être substituées indépendamment par alkyle C¿1?-C¿6?, alkoxy C¿1?-C¿6?, halogène, OCF¿3?, CF¿3?, CN, NO¿2?, méthylènedioxy ou éthylènedioxy; m est 0, 1 ou 2 ; q est 0, 1, 2, 3 ou 4; t est 0, 1, 2, ou 3; x et y sont indépendamment 0, 1, 2, 3, ou 4; ou un de ses sels acceptable sur le plan pharmaceutique; utile en tant que ligands du récepteur de CGRP (peptide apparenté au gène de calcitonine), procédés servant à le préparer, son utilisation thérapeutique, compositions pharmaceutiques le contenant et procédés de traitement le mettant en application.
Patent CA-2345887-A1 (CA)
Inventor: AUBUT GERALD
IPC: B42F7/06
Filed: 2001-05-01
Abstract: Disclosed herein is a page for displaying inserts, such as photos. The page comprises a backing sheet, a clear display sheet and at least one horizontal row of pockets for receiving the inserts.      The clear display sheet overlays at least one side of the backing sheet and is attached thereto about the backing sheet peripheral edge and along predetermined attachment patterns. The clear display sheet includes at least first and second openings, such as slits. The attachment patterns and the openings define a row of pockets. Two adjacent pockets of a given row share one of either first and second openings. A row of pockets may be used to display inserts, such as landscape photos, which span at least two adjacent pockets of this row. Also disclosed is an album including such pages, and a similar page in which the backing sheet includes at least first and second openings.
Patent CA-2349816-A1 (CA)
Title: Downhole well-control valve reservoir monitoring and drawdown optimization system
Inventor: JONES KEVIN R
IPC: E21B43/12
Filed: 2001-05-30
Abstract: A well control valve assembly having a downhole portion with a primary valve, and electromechanical actuator connected to the valve and a first wireless communicator connected to the actuator. The assembly further includes an uphole portion having a pump, a second wireless communicator complementary to the first wireless communicator and being supported in the uphole portion of the valve assembly. The downhole portion and uphole portion are physically non-connected and informationally connected.
Patent CA-2350052-A1 (CA)
Title: Pharmaceutical compositions containing poly(adp-ribose) glycohydrolase inhibitors and methods of using the same
Inventor: LI JIA-HE
IPC: A61K31/7024
Filed: 1999-11-01
Abstract: The present invention relates to pharmaceutical compositions containing poly(ADP-ribose) glucohydrolase inhibitors, also known as PARG inhibitors, and methods of using the same for inhibiting or decreasing free radical induced cellular energy depletion, cell damage, or cell death. More particularly, the present invention relates to pharmaceutical compositions containing poly(ADP-ribose) glucohydrolase inhibitors such as glucose derivatives; lignin glycosides; hydrolysable tannins including gallotannins and ellagitannins;  adenoside derivatives; acridine derivatives including 6,9-diamino-2-ethoxyacridine lactate monohydrate; tilorone analogs including tilorone R10.556, daunomycin or daunorubicin hydrochroride; ellipticine; proflavine;  and other PARG inhibitors; and their method of use in treating or preventing diseases or conditions due to free radical induced cellular energy depletion and/or tissue damage resulting from cell damage or death due to necrosis, apoptosis, or combinations thereof.