baber/WOPTO huggingface dataset:
Patent WO-2023168255-A1 (WO)
Title: Compositions d'anticorps monoclonal anti-c5
Inventor: IP ANNA
IPC: C07K16/18
Filed: 2023-03-01
Abstract: L'invention concerne des compositions pharmaceutiques comprenant un anticorps anti-C5. L'invention concerne également des méthodes comprenant l'administration de compositions pharmaceutiques. L'invention concerne également des procédés de fabrication de compositions pharmaceutiques.
Patent WO-2023196974-A1 (WO)
Inventor: THOMSON JAMES
IPC: A61K35/12
Filed: 2023-04-07
Abstract: Provided herein are allogeneic human endothelial cell-seeded polymeric vascular grafts suitable for replacing or bypassing natural blood vessels and exhibiting increased long term patency rates and reduced leukocyte adhesion relative to grafts comprising venous endothelial cells. Methods for generating the human endothelial cell-seeded vascular grafts and therapeutic uses of the same are also described.
Patent WO-2024011038-A1 (WO)
Title: Nettoyage et organisation de données semi-structurées sans schéma pour un traitement extract-transform-load
Inventor: MUDUMBA VENKATESHWARA
IPC: G06F16/25
Filed: 2023-06-27
Abstract: Dans certains modes de réalisation, un système peut obtenir, à partir d'un premier référentiel de données, un premier ensemble de données comprenant des données d'événement associées à un schéma générique. Le système peut déduire un schéma spécifique à l'événement, qui définit une structure organisationnelle pour les données d'événement sur la base d'attributs communs identifiés parmi une pluralité d'événements inclus dans les données d'événement, à l'aide d'une ou plusieurs fonctions d'analyse de données. Le système peut stocker, dans un second référentiel de données, un deuxième ensemble de données dans lequel les données d'événement sont partitionnées sur la base de la structure organisationnelle définie par le schéma spécifique à l'événement. Le système peut générer un troisième ensemble de données comprenant un sous-ensemble des données d'événement incluses dans le deuxième ensemble de données qui satisfait un ou plusieurs paramètres d'enregistrement associés à un cas d'usage extract-transform-load (ETL). Le système peut fournir le troisième ensemble de données à un système ETL configuré pour traiter le troisième ensemble de données sur la base du cas d'usage ETL.
Patent WO-2024007017-A1 (WO)
Inventor: MEHLEM JEREMY JOHN
IPC: C08B3/08
Filed: 2023-06-30
Abstract: This invention relates to improved cellulose nanocrystal fillers for rubber compositions and more specifically with the grafting of disulfide and thioesters onto cellulose nanocrystals for improved performance as a filler in rubber compositions. At least one embodiment describes a method to graft thiols or disulfides on CNC surfaces via esterification exemplified by 3-mercapto-propionic acid (MPA), 3-(acetylthio)propionic acid (APA), or dithiodipronanoic acid (DTDPA). The reaction may be carried out on CNCs highly dispersed in a suitable solvent and improved reaction conditions to achieve a favorable degree of substitution, DS. The embodiment further discloses how surface thiol groups can then be protected, in a second step, as thioesters or asymmetric disulfides to tune the hydrophobicity of CNCs to improve compatibility with styrene-butadiene, SBR, or natural rubbers.
Patent WO-2024015882-A1 (WO)
Title: Orthodontic treatment evaluation
Inventor: KIM WOOJAE
IPC: A61C7/00
Filed: 2023-07-12
Abstract: Devices, systems, and methods for orthodontic treatment, orthodontic treatment planning, and orthodontic treatment evaluation are disclosed herein. Various embodiments of the present technology, for example, are directed to a method of obtaining a plurality of digital models representing a patient's teeth in a variety of arrangements and displaying the digital models to an operator such as an orthodontist, a patient, etc. In some embodiments, the arrangements of the patient's teeth can comprise a predicted arrangement and/or an actual arrangement. V arious embodiments of the present technology relate to creating a more realistic final arrangement of a patient's teeth based on actual positions of brackets on the patient's teeth. Some embodiments relate to displaying two or more digital models of unique tooth and/or bracket arrangements to an operator via a graphical user interface to facilitate evaluation of the tooth and/or bracket arrangements.
Patent DK-201770817-A1 (DK)
Title: Screw with tapered screw-head, use of a screw and a method for countersinking the screw
Inventor: CLAUS HORNSTRUP DISSING
IPC: F16B35/06
Filed: 2017-11-01
Abstract: In order to prevent wood fringes at the edge of a hole from a countersunk screw (1), the screw-head (2) is provided with a tapering underside and inclined milling-ribs (8) on the tapering underside. Each milling-rib (8) has a planar front-side (15) delimited by smoothly curved convex milling-edge (17) for milling the material during countersinking of the screw-head (2).
Patent DK-201870523-A1 (DK)
Title: Kommunikationsstruktur til transmission af information
Inventor: STEFAN SCHMITZ
IPC: H04L12/14
Filed: 2018-08-13
Abstract: Kommunikationsstruktur med mindst en datasamler (7, 8) og en kommunikationsenhed (1), der kan forbindes med en central regneindretning (10), til transmission af information mellem den pågældende datasamler (7, 8) og den centrale regneindretning (10), hvor kommunikationsenheden (1) omfatter følgende: en datagrænseflade (2), ved hjælp af hvilken informationen i form af data kan transmitteres, hvor datagrænsefladen (2) omfatter et filsystem (3) til lagring af dataene i et første dataformat, og dataene i det første dataformat kan transmitteres ved hjælp af datagrænsefladen (2) ved hjælp af en første kommunikationsprotokol, der er tilvejebragt en datafordelerenhed (4), som er indrettet til at udføre transmissionen af dataene i et andet dataformat, der er forskelligt fra det første dataformat, ved hjælp af en anden kommunikationsprotokol, og der er tilvejebragt en databro (5) mellem filsystemet (3) og datafordelerenheden (4), hvor databroen (5) er indrettet til at importere data af det andet dataformat som data af det første dataformat til filsystemet (3) og/eller eksportere data af det første dataformat som data af det andet dataformat fra filsystemet (3).
Patent DK-201901264-A1 (DK)
Title: Apparatus for manufacturing fibers by electrospinning
Inventor: JØRGEN BECH POULSEN
IPC: D01D5/00
Filed: 2019-10-28
Abstract: The present invention relates to an apparatus for producing fibers such as nanofibers by lectrospinning liquid matrix in an electrostatic field. According to the present invention a single wire is used as a spinning electrode in an apparatus section to generate fibers. The apparatus comprises: - a first collecting electrode; - a second spinning wire electrode spaced from the first collecting electrode, the second spinning wire electrode comprises a moving strand or wire guided by first guiding means; - a wire driving unit moving the second spinning wire electrode forward; and - a liquid matrix application device applying liquid matrix to the second spinning wire electrode; the sheet of substrate travels along a first path in a first direction between the first collecting electrode and the second spinning wire electrode; and the second spinning wire electrode travels in a second direction approximately perpendicular to the first direction at an approximately constant operational distance to the sheet of substrate; wherein the apparatus comprises secondary guiding means guiding the second spinning wire electrode in a third direction parallel or at least partly parallel to the first direction i.e. at least partly parallel to the travelling direction of the sheet of substrate, and tertiary guiding means guiding the second spinning wire electrode in a fourth direction approximately perpendicular to the first direction and parallel but opposite the second direction at a constant operational distance to the sheet of substrate.
Patent PH-12013500578-A1 (PH)
Title: Substituted dihydropyrazolones for treating cardiovascular and haematological diseases
Inventor: THEDE KAI
IPC: C07D403/14
Filed: 2013-03-26
Abstract: The invention relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting the healing of wounds.
Patent PH-12013502291-A1 (PH)
Title: Dhea compositions for treating menopause
Inventor: FERNAND LABRIE
IPC: A61K31/453
Filed: 2013-11-11
Abstract: Novel methods for treating or reducing the likelihood of acquiring symptoms or diseases due to the menopause, in postmenopausal women, particularly osteoporosis, vaginal atrophy and dryness, hypogonadism, diminished libido, skin atrophy, connective tissue disease, urinary incontinence, breast, endometrial, ovarian and uterine cancers, hot flashes, loss of muscle mass, insulin resistance, fatigue, loss of energy, aging, physical symptoms of menopause, in susceptible warm-blooded animals including humans involving administration of a sex steroid precursor are disclosed. Said method comprising novel ways of administering and dosing dehydroepiandrosterone (DHEA) in order to take advantage of positive androgenic effects in the vaginal layers lamina propia and/or the layer muscularis, without undesirably causing systemic estrogenic effects in order to avoid the risk of breast and uterine cancer. Pharmaceutical compositions for delivery of active ingredient(s) useful to the invention are disclosed.
Patent PH-12014501650-A1 (PH)
Title: Food dispenser
Inventor: STEFAN SCHEUCH
IPC: B65D75/58
Filed: 2014-07-18
Abstract: A food dispensing apparatus suitable for use with a food storage means and for providing a wrapped food product, which is at least partly covered with a wrapper. Further, the food dispensing apparatus has redirecting means for redirecting the wrapper away from the food product to opposite faces in order to separate the wrapper and to dispense the food product. Feeding means transport the food product for feeding the wrapped food product towards the redirecting means, where the food product is unwrapped and dispensed.
Patent PH-12014502663-A1 (PH)
Title: Aromatic heterocyclic derivative and pharmaceutical
Inventor: KATSUTOSHI HORI
IPC: C07D417/14
Filed: 2014-11-28
Abstract: The main purpose of the invention is to provide a novel aromatic heterocyclic derivative or a pharmaceutically acceptable salt thereof. Examples of the invention include aromatic heterocyclic derivatives represented by general formula [1] and pharmaceutically acceptable salts thereof. In formula [1], R1 represents phenyl optionally substituted with one or two groups selected from the group consisting of halogens, as well as alkyls and alkoxys optionally substituted by halogens; R2 represents a hydrogen, an alkyl, cycloalkyl, or alkoxy optionally substituted by a halogen, or a heteroaryl optionally substituted by an alkyl; X represents CR3, and Y represents N or CR4, or X represents N, and Y represents CR4; and Z represents CR5 or N.
Patent PH-12017500432-A1 (PH)
Title: A flavor modifying composition, uses thereof and products comprising the same
Inventor: MAYMON YUVAL
IPC: A23L29/25
Filed: 2017-03-08
Abstract: The present disclosure provides a flavor modifying composition comprising a blend of a water soluble filler comprising plant fibers; and at least one sucrose substitute of natural source, wherein said flavor modifying composition comprises at least 90 pcnt w/w of the filler, the amount being determined when said composition is in dry form; and said flavor modifying composition is water soluble. The flavor modifying composition is particularly effective in enhancing sweet taste and/or aroma of a product. Also disclosed herein are products comprising the flavor modifying composition.
Patent PH-12017500979-A1 (PH)
Title: Anticancer compositions
Inventor: VERRECK GEERT
IPC: A61K9/20
Filed: 2017-05-26
Abstract: The present invention concerns pharmaceutical formulations of ARN-509, which can be administered to a mammal, in particular a human, suffering from an androgen receptor (AR)-related disease or condition, in particular cancer, more in particular prostate cancer, including but not limited to castration-resistant prostate cancer, metastatic castration resistant prostate cancer, chemotherapy-naive metastatic castration resistant prostate cancer, biochemically relapsed hormone sensitive prostate cancer, or high-risk, non-metastatic castration-resistant prostate cancer. In one aspect, these formulations comprise a solid dispersion of ARN-509, a poly(meth)acrylate copolymer and HPMCAS. In one aspect, the solid dispersion of ARN-509, a poly(meth)acrylate copolymer and HPMCAS is obtainable, in particular is obtained, by melt-extruding a mixture comprising ARN-509, a poly(meth)acrylate copolymer and HPMCAS and optionally subsequently milling said melt-extruded mixture. In one aspect, the solid dispersion of ARN-509, a poly(meth)acrylate copolymer and HPMCAS is obtainable, in particular is obtained, by spray drying a mixture comprising ARN-509, a poly(meth)acrylate copolymer and HPMCAS in a suitable solvent.
Patent PH-12018500030-A1 (PH)
Title: FORMULATIONS FOR ANTI-a4á7 ANTIBODY
Inventor: DILUZIO WILLOW
IPC: C07K16/28
Filed: 2018-01-03
Abstract: Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-a4á7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-a4á7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-a4á7 antibody in vivo.
Patent PH-12018501421-A1 (PH)
Title: Packaging bag
Inventor: HARA MASATO
IPC: B65D81/34
Filed: 2018-07-03
Abstract: A packing pouch in which improvement is made for vapor exhaust is provided. A packing pouch including a seal section (8a) formed by sealing circumferential edge sections of a film constituting an upper surface section and a film constituting a lower surface section is characterized by comprising a vapor exhaust seal section (7) formed by projecting part of the seal section (8a) in an inflection shape toward an inner direction, wherein in the vapor exhaust seal section (7), the seal width differs, at least in the inner direction relative to the seal section (8a), between a tip end section and the other section, and the tip end section is narrow; and when the packing pouch expands and the vapor exhaust seal section (7) peels off, the other section remains, and the remaining other section forms an edge section (7a) projecting in the inner direction from the seal section (8a).
Patent PH-12019501167-A1 (PH)
Title: Systems and methods for communicating via a track with an industrial cart
Inventor: MILLAR GARY BRET
IPC: B61L3/24
Filed: 2019-05-27
Abstract: A system includes a track having conductive rails, a signal generating circuit coupled to the conductive rails, and an electrical power source coupled to the conductive rails via the signal generating circuit. The signal generating circuit includes a power supply for generating trigger signals. The electrical power source provides an electrical signal to the conductive rails via the signal generating circuit. The signal generating circuit generates a first trigger signal within the electrical signal at a first time interval and generates a second trigger signal within the electrical signal at a second time interval. The first trigger signal corresponds to a beginning of a communication signal and the second trigger signal corresponds to an end of the communication signal. The communication signal is transmitted over a predetermined number of cycles of the electrical signal provided by the electrical power source. The predetermined number of cycles correspond to a coded communication.
Patent PH-12020500240-A1 (PH)
Title: Anti-cd39 antibodies, compositions comprising anti-cd39 antibodies and methods of using anti-cd39 antibodies
Inventor: SOROS VANESSA
IPC: G01N33/574
Filed: 2020-01-31
Abstract: Provided herein are antibodies that selectively bind to CD39 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.
Patent PH-12020500622-A1 (PH)
Title: 17á-HYDROXYSTEROID DEHYDROGENASE TYPE 13 (HSD17B13) IRNA COMPOSITIONS AND METHODS OF USE THEREOF
Inventor: HINKLE GREGORY
IPC: C12N15/113
Filed: 2020-08-19
Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the HSD17B 13 gene, as well as methods of inhibiting epression of HSD17B13, and methods of treating subjects that would benefit from reduction in expression of HSD17B13, such as subjects having a HSD17B13-associated disease, disorder, or condition, using such dsRNA compositions.
Patent PH-12020551060-A1 (PH)
Title: Methods of treating chronic inflammatory diseases
Inventor: CHANG CHONG-HWAN
IPC: A61K9/00
Filed: 2020-07-09
Abstract: The invention relates to method of treating chronic inflammatory diseases in subjects in need thereof by administering calcium lactate as an active agent. The calcium lactate can be provided in a pharmaceutical, food, or nutrient composition.
Patent DE-102004001358-A1 (DE)
Title: Regelverfahren und Regeleinrichtung für einen Aktor
Inventor: MARZAHN GABRIEL
IPC: F02D41/20
Filed: 2004-01-08
Abstract: Die Erfindung betrifft ein Regelverfahren für einen Aktor (3) zur Ansteuerung eines Injektors einer Einspritzanlage für eine Brennkraftmaschine, mit den folgenden Schritten: Vorgabe eines Soll-Werts (t¶NO,Soll¶) für eine das Einspritzverhalten bestimmende Einspritzgröße, elektrische Ansteuerung des Aktors (3) mit einem elektrischen Steuersignal entsprechend dem vorgegebenen Soll-Wert (t¶NO,Soll¶) für die Einspritzgröße, Erfassung eines Ist-Werts (t¶NO,ist¶) der Einspritzgröße und Regelung der Einspritzgröße durch eine Einstellung des Steuersignals in Abhängigkeit von dem ermittelten Ist-Wert (t¶NO,Ist¶) der Einspritzgröße. Es wird vorgeschlagen, dass im Rahmen der Regelung mindestens ein erster Parameter (t¶i,NOM¶) und ein zweiter Parameter (E¶NOM¶) des Steuersignals eingestellt werden.
Patent DE-102004003040-A1 (DE)
Title: Schnee-Eis-Schuh zum Gehen auf Schnee oder Eis
Inventor: CUTANDO SORIANO ANTONIO
IPC: A63C13/00
Filed: 2004-01-20
Abstract: Schnee-Eis-Schuh zum Gehen auf Eis oder Schnee, bestehend aus Schneeschuhen, auf deren Oberseite Steighilfen zur Befestigung mit Stiefeln o. dgl. lösbar angeordnet sind, wobei die Steighilfen unter ihrer Absatzplatte eine Kipp-/Schwenkvorrichtung aus einem sphärischen oder ähnlichen Drehelement mit einer Durchtrittsöffnung haben, durch die eine Achse geführt ist, an deren Enden Befestigungshaken sitzen, die an der Unterseite der Steighilfe in Lager einrasten, wobei an der Unterseite der Steighilfen und an der Unterseite der Schneeschuhe Stifte vorgesehen sind.
Patent DE-102004005375-A1 (DE)
Title: Sealing method, e.g. for a flat roof, with upper and lower sealing layers deposited and sealed tightly around the edges so that an intermediate space is created for a connector element
IPC: E04D5/02
Filed: 2004-02-03
Abstract: Method for creating sealing layers for multi-layer systems, e.g. for the ground, roofs, roadways or terraces in which a sealing layer comprising at least upper and lower layers of sealing material is deposited on a base layer. Next the two layers are jointed, at least around the outer edges. A connection element is connected to at least one point in the intermediate space between the upper and lower layers, for use in subsequent testing. If required, a load bearing layer is deposited on top of the sealing layer. The invention also relates to a sealing layer and a testing method.
Patent DE-102004007969-A1 (DE)
Title: Lubricated rider for machine tool horizontal beam has an end-cap frame incorporating three-dimensional oil passages
Inventor: LIN ANITA
IPC: F16C29/06
Filed: 2004-02-18
Abstract: A machine tool has a horizontal beam with a lubricated rider (10) for a workpiece clamp. The rider has a saddle-shaped cross section with internal lubrication passages for internal ball bearings. Each end of the rider is linked to an and-cap (20) by a cover frame (30) incorporating three-dimensional oil-return passages. Oil is transmitted through the upper mid-point and lower return passage and is distributed uniformly on the upper and lower rider passage surfaces. The oil inlet is located on the end-cap outer face at centre.
Patent DE-102004009784-A1 (DE)
Title: Radiation therapy monitoring PET signal correction procedure combines measured signals using only events when beam below threshold
Inventor: ENGHARDT WOLFGANG
IPC: A61N5/10
Filed: 2004-02-28
Abstract: A radiation therapy monitoring PET (Positron Emission Tomography) signal correction procedure combines measured signals during Macropulses with positron camera annihilation events and beam intensity data so that sub microsecond intensity changes in accelerator radiation are recorded and events are used for reconstruction only when the beam is below a threshold set by the maximum noise amplitude.
Patent DE-102004011265-A1 (DE)
Title: Preparation of chroman compounds, useful to prepare vitamin E compounds, which are useful as antioxidants, comprises reaction of phenol compounds with alkene compounds, catalysts (with chiral or achiral ligand) and oxidizing agents
Inventor: TIETZE LUTZ F
IPC: C07D311/72
Filed: 2004-03-09
Abstract: Preparation of chroman compounds (I) comprises providing phenol compounds (II), an alkene compound (III) and catalyst with chiral or achiral ligand; and contacting (II) with (III) in the presence of the catalyst and an oxidizing agent under conditions, where (II) and (III) undergo catalyst-mediated reaction to form (I). Preparation of chroman compounds of formula (I) comprises providing phenol compounds of formula (II), an alkene compound of formula (III) and catalyst with chiral or achiral ligand; and contacting (II) with (III) in the presence of a catalyst and an oxidizing agent under suitable conditions, where (II) and (III) undergo catalyst-mediated reaction to form (I). R1>-R4>H, 1-6C alk(en)yl, benzyl, phenyl (optionally substituted by 1-6C alk(en)yl), OH, OR7>, NR7>R7>, CN, NO2 or COOR7>; R5>, R6>1-16C alk(en)yl (optionally substituted by =O, OH, OR7>, NR7>R7>, CN, halo, NO2 or CO2R10); X : H; B(OR11>)2 or Sn(R12>)3; R11>H, 1-6C alkyl, benzyl or phenyl; R12>1-6C alkyl, benzyl or phenyl; R13>-R15>H, 1-15C alk(en)yl (optionally substituted by =O, OH, OR7>, NR7>R7>, CN, halo, NO2 or CO2R7>); and R7>H, 1-6C alk(en)yl, benzyl, phenyl (optionally substituted by 1-6C alk(en)yl), or protecting groups for OH-, NH2- or carboxyl functions. An independent claim is also included for the preparation of vitamin E comprising providing phenol compounds (possessing, in ortho position to the phenolic hydroxy group, a side chain with one gamma -carbon atom, which carries both substituted double bound =CH2 and R5>) and stereo selective ring closure by formation of a bond between the oxygen atom of the phenolic hydroxy group and the gamma -carbon atom. [Image].