baber/WOPTO huggingface dataset:
Patent CA-2919498-C (CA)
Inventor: SURBER MARK WILLIAM
IPC: A61K9/72
Filed: 2014-07-31
Granted: 2023-07-25
Abstract: Disclosed herein are formulations of nintedanib or a salt thereof for aerosolization and use of such formulations for inhaled aerosol administration of nintedanib or a salt thereof for the prevention or treatment of various fibrotic, carcinogenic, vascular and viral infectious diseases, including diseases associated with the lung, heart, kidney, liver, eye, central nervous system and surgical sites. In some embodiments, formulations and delivery options described herein allow for efficacious local delivery of nintedanib or a salt thereof. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures, indications and manufacturing processes for production and use of the compositions described. Also included are methods for identifying compounds and indications that may benefit by reformulation and inhalation administration.
Patent CA-2919791-C (CA)
Inventor: YOUNG GRAEME
IPC: F16B15/06
Filed: 2014-07-21
Granted: 2019-05-07
Abstract: Disclosed is an assembly of staples (18), the staples (18) having a crown portion (34) having at least two legs (42) extending therefrom and one or more barbs (40) protruding from at least one of the legs (42), the assembly further including at least one strip of collation tape (44), wherein the staples (18) are collated and connected by way of the at least one strip of collation tape (44) secured to the staples (18). In one form a portion of the collation tape (44) remain affixed to the staples (18) when driven by driver blade in a powered staple tool and assists in maintaining alignment of the staple (18) in a nosepiece of the tool.
Patent CA-2923307-C (CA)
Inventor: THORNTON PATRICK
IPC: E04C3/42
Filed: 2014-09-05
Granted: 2022-09-27
Abstract: Timber structural members based on timber rounds or peeler cores are used in building construction to fabricate a load bearing component of a building such as a floor bearer, a floor joist, a lintel, a heavy duty stud, a roof framing member, a roof rafter, a roof hanging/strutting beam, a portal frame member, a column, a bottom chord, a beam/column, or a pier. Timber rounds are secured together to form a structurally integral unit using fasteners provided at both acute and obtuse angles from a longitudinal axis of the structural member.
Patent CA-2924861-C (CA)
Title: Procede et systeme de mise en place d'un mandataire securise de secrets
Inventor: CABRERA LUIS FELIPE
IPC: H04L9/32
Filed: 2014-09-30
Granted: 2023-03-14
Abstract: L'invention concerne un procédé caractérisé en ce qu'un mandataire sécurisé de secrets est instancié dans un premier environnement informatique et comprend des données d'authentification de mandataire sécurisé de secrets lui permettant de s'identifier vis-à-vis d'un système de gestion de distribution de secrets dans un deuxième environnement informatique en tant qu'actif virtuel de confiance pour recevoir et mettre en antémémoire des données de secrets dans une antémémoire sécurisée de secrets à l'extérieur du deuxième environnement informatique. Le mandataire sécurisé de secrets demande un ou plusieurs secrets à mettre en antémémoire et des données représentant les secrets demandés lui sont alors transmises dans l'antémémoire sécurisée de secrets. Le mandataire sécurisé de secrets reçoit ensuite des données de demande d'application de secrets en provenance d'un deuxième actif virtuel instancié dans le premier environnement informatique demandant qu'un ou plusieurs secrets soient appliqués à des données du deuxième actif virtuel. Le mandataire sécurisé de secrets obtient ensuite les secrets nécessaires à partir de l'antémémoire sécurisée de secrets et coordonne l'application des secrets aux données du deuxième actif virtuel.
Patent CA-2929531-C (CA)
Inventor: XU JIANGUO
IPC: C01B3/56
Filed: 2016-05-10
Granted: 2018-01-02
Abstract: Process for producing hydrogen where multiple streams are heated in parallel with reformate that has passed from the shift reactor. Each of the multiple streams are heated from a temperature below the dew point of the reformate to a temperature above the dew point of the reformate by reformate that is cooled from a temperature above the dew point of the reformate to a temperature below the dew point of the reformate. The multiple streams can include two or more of water condensate, boiler feed water, hydrocarbon feedstock, and pressure swing adsorption unit by-product gas.
Patent CA-2930359-C (CA)
Inventor: DI TOMASO EMMANUELLE
IPC: A61P35/00
Filed: 2014-12-03
Granted: 2022-03-01
Abstract: La présente invention concerne un composé inhibiteur de la phosphatidylinositol 3-kinase sélectif de l'isoforme alpha de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci destiné à être utilisé dans des méthodes de traitement ou de prévention d'une maladie proliférative chez un patient qui en a besoin en administrant par voie orale une quantité thérapeutiquement efficace dudit composé pendant au moins deux cycles de 5 jours consécutifs, ledit composé n'étant pas administré au patient pendant une période d'environ deux jours à environ trois jours entre lesdits cycles de cinq jours consécutifs.
Patent CA-2930417-C (CA)
Title: Corneal vitrification, methods and devices to produce corneal vitrification and methods of use thereof
Inventor: SERDAREVIC OLIVIA
IPC: A61L27/38
Filed: 2014-10-13
Granted: 2018-08-21
Abstract: The invention includes: a new composition of matter (a composite comprising a naturally occurring in vivo cornea in an in situ eye together with at least one volume of vitrified non-naturally occurring corneal stromal tissue formed within the naturally occurring corneal stromal tissue) wherein the vitrified tissue is modified in structure and properties from its naturally occurring condition into a non-naturally occurring glass-like condition with modifications including but not limited to increased elastic modulus; methods for producing and using the new composition of matter for modifying cornea! structure and properties, including but not limited to corneal optical aberrations; wound closure adhesion and transplant adhesion; and a photovitrification system for producing the new composition of matter comprising at least one photon source with controllable treatment parameters. A reverse template can be added to corneal vitrification systems to increase vitrification and modifications of structure and properties.
Patent CA-2930594-C (CA)
Title: Optimizing operating binding capacity for a multiple column chromatography process
Inventor: GJOKA XHORXHI
IPC: B01D15/14
Filed: 2016-05-20
Granted: 2019-09-03
Abstract: Methods for determining the optimum operating binding capacity for a multiple column chromatography (MCC) using a single column are taught. A target is loaded on a first column at a first residence time and/or flow rate (RT/FR). The target is loaded on the first column at a second RT/FR. Breakthrough curves are generated for the first and second RT/FR. The breakthrough curves are used to determine target product loading capacity of the first column before target product breakthrough at the Nth column. The target product loading capacity of the first column equals the optimum operating binding capacity for the MCC process. Accurate prediction of the operating capacities enables estimation of other multi-column process parameters such as productivity, cycle time, total number of columns, and buffer utilization. A range of flow rates provides data which can be interpolated to optimize parameters of interest as a function of residence time.
Patent CA-2931828-C (CA)
Title: Simple method and kit for dna typing of hla genes by high-throughput massively parallel sequencer
Inventor: SHIINA TAKASHI
IPC: C12Q1/686
Filed: 2014-11-27
Granted: 2022-07-12
Abstract: [Problem] The present invention addresses the problem of providing a method and kit for the DNA profiling of HLA genes using a high-throughput massively parallel sequencer. [Solution] The present invention pertains to a method for the DNA profiling of HLA genes, said method being characterized by including: (1) a step for preparing a primer set that anneals specifically to exon 4 and intron 1 and includes exon 2 and exon 3 of at least one target gene selected from the group consisting of HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DQB1 and HLA-DPB1 in the base sequence of the human genome; (2) a step for amplifying a sample (DNA) by PCR using the primer set; (3) a step for determining the base sequence of the amplified PCR product; and (4) a step for carrying out a homology search against a database.
Patent CA-2932016-C (CA)
Inventor: INOUE YUICHI
IPC: H01M8/02
Filed: 2014-12-01
Granted: 2019-06-11
Abstract: The present invention provides a polymer electrolyte membrane having excellent strength, a small dimensional change, and a low membrane resistance. The polymer electrolyte membrane includes a porous film and a polymer electrolyte. The porous film has a fibril/node area ratio of 90/10 to 75/25.
Patent CA-2932017-C (CA)
Title: Microbial production of fatty amines
Inventor: DEL CARDAYRE STEPHEN B
IPC: C12N9/16
Filed: 2014-12-05
Granted: 2021-05-25
Abstract: The disclosure relates to recombinant microorganisms for the production of fatty amines and derivatives thereof. Further contemplated are cultured recombinant host cells as well as methods of producing fatty amines by employing these host cells.
Patent CA-2934052-C (CA)
Title: Blade for a turbo machine impeller and method for modelling the same
Inventor: BENICHOU SAMI
IPC: F01D5/22
Filed: 2014-12-08
Granted: 2023-02-21
Abstract: Blade for a turbo machine impeller comprising a root, an air foil and a tip. The root and the tip comprise platforms having surfaces (15) on the side of the air foil, the surfaces respectively being referred to as the root and tip flow path. Each of these flow paths is made up of a pressure-face part and of a suction-face part which are situated respectively on the side of the pressure face and of the suction face and are separated by a crest curve (45, 65). Blade manufacture is made easier notably by virtue of the fact that any point on a first surface out of the pressure face and the suction face and any point on the root and tip flow path parts situated on the side of the first surface has a normal that makes an acute or right angle with respect to a direction referred to as the first direction of manufacture. Method for modelling the blade.
Patent CA-2940068-C (CA)
Title: Downhole deployment valves
Inventor: NOSKE JOE
IPC: E21B34/06
Filed: 2008-03-31
Granted: 2019-12-10
Abstract: Methods and apparatus enable reliable and improved isolation between two portions of a bore extending through a casing string disposed in a borehole. A downhole deployment valve (DDV) may provide the isolation utilizing a valve member such as a flapper that is disposed in a housing of the DDV and is designed to close against a seat within the housing. The DDV includes an operating mechanism for opening/closing the DDV. In use, pressure in one portion of a well that is in fluid communication with a well surface may be bled off and open at well surface while maintaining pressure in another portion of the casing string beyond the DDV.
Patent CA-2940819-C (CA)
Title: Appareil et procede d'obtention d'une interface de decoration virtuelle
Inventor: SONNENBERG MARKO
IPC: G06F30/13
Filed: 2015-02-27
Granted: 2023-03-28
Abstract: Selon des modes de réalisation, la présente invention concerne un procédé d'obtention d'une interface de décoration pour traitement d'une fenêtre virtuelle, qui comprend la réception, par un processeur, de données de fenêtres relatives à une ou plusieurs fenêtres d'un lieu, l'utilisation d'une interface utilisateur afin de sélectionner un traitement de fenêtres pour lesdites fenêtres, la restitution de l'une desdites fenêtres dans l'interface utilisateur, cette restitution étant générée sur la base des données de fenêtres, la réception de la sélection d'un traitement de fenêtre à appliquer à la fenêtre restituée, et la restitution du traitement de fenêtre sur la fenêtre restituée dans l'interface utilisateur. De préférence, le procédé inclut la définition des dimensions de la fenêtre et du traitement de fenêtre restitués de manière à ce qu'ils correspondent à des données de mesure professionnelle de la fenêtre, pour obtenir une visualisation virtuelle précise de la fenêtre avec le traitement sélectionné.
Patent CA-2943785-C (CA)
Title: Toothed belt
Inventor: SHAKUSHIRO TOMOAKI
IPC: F16G1/28
Filed: 2015-03-25
Granted: 2021-01-05
Abstract: The present invention pertains to a toothed belt equipped with a back section, a tooth section, and core wires embedded in the back section. The back section and the tooth section include a urethane resin composition, and the core wires are twisted cords comprising a group of glass fiber filaments, or are twisted cords comprising a group of polyarylate fiber filaments. When the core wires are twisted cords comprising a group of glass fiber filaments, the pitch of the tooth section is 0.45-0.60 mm, the diameter of the glass fiber filaments is 6-9 microns, and the wire diameter of the core wires is 0.14-0.20 mm. When the core wires are twisted cords comprising a group of polyarylate fiber filaments, the pitch of the tooth section is 0.45-0.71 mm, and the wire diameter of the core wires is 0.14-0.28 mm.
Patent CA-2947303-C (CA)
Title: Keratin treatment formulations and methods
Inventor: PRESSLY ERIC D
IPC: A61K8/36
Filed: 2015-05-15
Granted: 2020-06-16
Abstract: Formulations, kits, and methods for rebuilding the disulfide bonds in keratin found in hair, skin, or nails. Hair that is damaged due to a hair coloring treatment and/or other reducing treatment, such as during a permanent wave, can be treated with the formulations containing one or more active agents. The formulations may be applied subsequent to a hair coloring treatment or simultaneously with a hair coloring treatment. Use of the active agent formulations during a permanent wave treatment prevents the reversion of the hair to its previous state, for at least one week, preferably at least three months, more preferably at least one year, most preferably greater than one year, after one or more than one application of the formulation. Application of the active agent formulation to skin or nails can help repair damaged disulfide bonds due to natural wear and tear or natural aging.
Patent CA-2947542-C (CA)
Title: Interiorly supported edible structure and related methods
Inventor: MAY JASON
IPC: A21D13/40
Filed: 2016-11-04
Granted: 2021-06-22
Abstract: Implementations of edible structures may include: at least four walls, each wall having an inner side and an outer side, at least one flexible interior wall support coupled to the inner sides of the at least four walls where the width of the at least one flexible interior wall support is less than the height of any of the at least four walls, a roof having two or more roof sections, wherein the roof is configured to rest on the at least four walls, each roof section having an inner side and an outer side, and at least one flexible interior roof support coupled to the inner sides of the two or more roof sections, wherein the at least one flexible interior roof support is not directly connected to the at least one flexible interior wall support.
Patent CA-2954535-C (CA)
Inventor: MEZA HUMBERTO V
IPC: F04B53/22
Filed: 2015-07-08
Granted: 2020-07-14
Abstract: L'invention porte sur une pompe, qui comporte un moteur, une tête de pompe (PH) et une broche de verrouillage (LP) qui sont accouplés de façon unique entre eux. Le moteur comprend une cloche d'extrémité avant (FEB) dotée d'une partie d'accouplement de cloche d'extrémité avant constituée de liaisons du type à verrou tournant (TLS) comprenant des parties de verrouillage, et une surface externe comprenant un cran. Chaque partie de verrouillage vient en prise avec une partie de verrouillage correspondante respective quand la partie d'accouplement de cloche d'extrémité avant et la partie d'accouplement de tête de pompe sont torsadées ensemble l'une par rapport à l'autre autour de l'axe longitudinal de la pompe. Chaque butée de verrouillage bute contre une partie de verrouillage respective de façon à arrêter la torsion l'une avec l'autre de la partie d'accouplement de cloche d'extrémité avant et de la partie d'accouplement de tête de pompe, de telle sorte que le cran et l'orifice fileté sont alignés de façon à recevoir la broche de verrouillage, et que le moteur et la tête de pompe sont verrouillés l'un à l'autre et ne peuvent pas être écartés l'un de l'autre.
Patent CA-2956924-C (CA)
Inventor: RAO GOVIND
IPC: C07K1/36
Filed: 2015-07-31
Granted: 2023-08-01
Abstract: A bioprocessing system for protein manufacturing from human blood is provided that is compact, integrated and suited for on-demand production and delivery of therapeutic proteins to patients. The patient's own blood can be used as the source of cell extracts for the production of the therapeutic proteins.
Patent CA-2958197-C (CA)
Title: External pulse generator device and associated methods for trial nerve stimulation
Inventor: SCHROEDER DENNIS
IPC: A61N1/05
Filed: 2015-08-14
Granted: 2023-09-26
Abstract: Systems and methods for providing a trial neurostimulation to a patient for assesssing suitability of a permanently implatned neurostimulation are provided herein. In one aspect, a trial neurostimulation system includes an EPG patch adhered to a skin surface of a patient and connected to a lead extending through a percutaneous incission to a target tissue location. The EPG may be a modified version of the IPG used in the permanent system, the EPG may be smaller and/or lighter than the corresponding IPG device. The EPG and a lead extension may be sealed to allow improved patient mobility and reduced risk of infection. The EPG may be compatible with wireless systems used to control and monitor the IPG such that operation and control of the EPG is substantially the same in each system to allow seemless conversion to the permantly implanted system
Patent CA-2965731-C (CA)
Inventor: VILLEMOES LARS
IPC: G10L19/008
Filed: 2015-10-28
Granted: 2023-12-05
Abstract: Selon l'invention, dans une section de codage (100), une section de mixage réducteur (110) forme des premier et second canaux (L 1 , L 2 ) d'un signal de mixage réducteur sous la forme de combinaisons linéaires de premier et second groupes (401, 402) de canaux, respectivement, d'un signal audio à M canaux ; et une section d'analyse (120) détermine des paramètres de mélange élévateur ((a LU ), pour une reconstruction paramétrique du signal audio, et des paramètres de mélange (a LM ). Dans une section de décodage (1200), une section de décorrélation (1210) délivre un signal décorrélé (D) sur la base du signal de mixage réducteur ; et une section de mélange (1220) détermine des coefficients de mélange sur la base des paramètres de mélange ou des paramètres de mélange élévateur, et forme un signal de sortie à K canaux (L? 1 ,...,L? K ) sous la forme d'une combinaison linéaire du signal de mixage réducteur et du signal décorrélé selon les coefficients de mélange. Les canaux du signal de sortie se rapprochent des combinaisons linéaires de K groupes (501-502, 1301-1303) de canaux, respectivement, du signal audio. Les K groupes constituent une partition du signal audio différente des premier et second groupes, et 2 = K < M.
Patent CA-2968123-C (CA)
Inventor: BELL PATRICK G
IPC: A01F25/22
Filed: 2017-05-26
Granted: 2021-03-30
Abstract: A grain dying system for a grain bin that includes a heating unit arranged in a proximity of the grain bin and ducting connected at one end to the heating unit and another end to a grain drying adaptor. The grain drying adaptor is connected at one end to the ducting and at another end to a fain unit of an aeration system for the grain bin. The fan unit is attached to the grain drying adaptor. The grain drying adaptor is configured to introduce a blend of heated air from the heating unit and ambient air from outside the grain drying adaptor into the aeration system of the grain bin.
Patent CA-2968209-C (CA)
Title: Methods and systems for spectral analysis of sonar data
Inventor: LIM HOCK-SIONG
IPC: G01S15/50
Filed: 2014-12-02
Granted: 2023-04-18
Abstract: Methods and systems are presented for spectral analysis of data generated by one or more sonar sensors. A covariance matrix of the captured sound is derived, denoted by an LxL matrix R, and for each power value which is to be calculated for each direction, a set w of L weights are derived which minimize w H Rw subject to a constraint which is itself a function of a covariance matrix of sound captured by the sensors or based on a theoretical noise model. The set of weights w is used to produce a power spectrum at a particular time instant. Embodiments of the invention can be used to compute two types of spectrum: (i) a spatial spectrum and (ii) a frequency spectrum (or, by extension, a Doppler spectrum). That is, it may be performed in either the spatial or the frequency domain.
Patent CA-2972461-C (CA)
Title: Multilayer films and related uses thereof
Inventor: ZANETTI MAXIMILIANO
IPC: B32B3/24
Filed: 2015-12-15
Granted: 2023-05-09
Abstract: Embodiments disclosed herein include multilayer films that have at least two layers. More particularly, disclosed in embodiments herein are multilayer films that include at least a first layer and a second layer, wherein the first layer includes at least one polyethylene polymer, wherein the second layer includes at least one water-soluble polymer, wherein the second layer is insoluble in water at a temperature of less than 20°C, wherein the second layer is soluble in water at a temperature of 20°C or greater, and wherein the first layer has one or more openings through the first layer to expose the second layer. Also disclosed herein are methods of using such multilayer films for extracting metal from metal ore.
Patent CA-2975349-C (CA)
Inventor: WOOD JAMES
IPC: B23P9/00
Filed: 2016-01-29
Granted: 2019-06-18
Abstract: A method of generating compressive residual stresses through a thickness of a metal component comprising the steps: receiving a metal base component (10), which in use is subjected to applied pressure and applying by thermal deposition cladding (16) to one or more surfaces (14) of the base component. The cladding (16) comprises one or more layers of metal or metal alloy. The method also includes, subsequent to the cladding step, applying autofrettage to the clad component thereby generating compressive residual stresses through the one or more layers of metal or metal alloy (16) and at least part way through the base component.
Patent CA-2981353-C (CA)
Title: Multi-channel wide field imaging system and optical system for use therein
Inventor: MOORE FREDERICK ALLEN
IPC: G01J3/36
Filed: 2016-03-29
Granted: 2020-02-25
Abstract: An optical system for use with a multi-channel wide field imaging system, the optical system including an objective lens, a dichroic element to split light into a first wavelength range and a second wavelength range, the dichroic element positioned to receive near parallel chief rays from the objective lens, a first channel lens system to receive light of the first wavelength range from the dichroic element; and a second channel lens system to receive light of the second wavelength range from the dichroic element.
Patent CA-2987034-C (CA)
Title: Use of an organic citrus extract with high antimicrobial capacity and xylitol as a preservative system in liquids, emulsions, suspensions, creams and antacids
Inventor: Barraza Javier
IPC: A61K47/46
Filed: 2016-05-26
Granted: 2023-03-07
Abstract: Liquid antacid compositions containing citrus extract are disclosed. The liquid antacid compositions possess superior resistance to microbial attack.