baber/WOPTO huggingface dataset:
Patent CA-2469714-A1 (CA)
Inventor: SCHUMAN RICHARD F
IPC: A61P31/04
Filed: 2002-12-23
Abstract: The present invention encompasses protective monoclonal antibodies that bind to peptidoglycan of Gram-positive bacteria. The antibodies also bind to whole bacteria and enhance phagocytosis and killing of the bacteria in vitro and block nasal colonization by Gram-positive bacteria in vivo. The invention also provides human, humanized and chimeric antibodies. The invention also sets forth the heavy chain and light chain variable regions of an antibody within the invention.
Patent CA-2469828-A1 (CA)
Title: Device for the hot granulation of thermoplastic polymers
Inventor: CASALINI ALESSANDRO
IPC: B29C48/05
Filed: 2002-12-05
Abstract: Device for the hot granulation of thermoplastic polymers, optionally expandable, which comprises: a) a die (1) containing a series of small plates (6), equipped with a series of extrusion holes, and a plurality of feeding ducts (3) situated inside the die body (2) in correspondence with the perforated small plates (6), lined with a material having a high thermal conductivity (4); b) a cutting chamber comprising a set of spraying nozzles (17) which create a jet of drops of a thermostat-regulating liquid for cooling the cut granules; c) a cutting system comprising a cutting plate (13) supporting a set of knives (15) arranged so that the cutting profile of the knife is radial with respect to the die.
Patent CA-2469884-A1 (CA)
Title: 7-amino-benzothiazole derivatives as adenosine receptor ligands
Inventor: RIEMER CLAUS
IPC: A61P7/08
Filed: 2002-12-05
Abstract: The present invention relates to the compounds of the general formula (I). It has been found that the compounds of general formula (I) are adenosine receptor ligands. Secifically, the compounds of the present invention have a good affinity to the A2A-receptor and they are therefore useful in the treatment of diseases, related to this receptor.
Patent CA-2476214-A1 (CA)
Title: Proliferated cell lines and uses thereof
Inventor: CAMERON DON F
IPC: A61K35/26
Filed: 2003-02-07
Abstract: The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines and cultures. The invention also concerns proliferation factors, and compositions containing the factors, which are capable of increasing the proliferation potential of any human or other animal cell in culture. The subject invention further pertains to a method for proliferating cells in culture by contacting cells with the proliferation factors. The proliferated cells can range in plasticity and can include, for example, blast cells, fertilized ova, non~fertilized gametes, embryonic stem cells, adult stem cells, precursor or progenitor cells, and highly specialized cells. Optionally, the cells can be induced to cease proliferation. The proliferated cells of the subject invention are useful for cell therapy, cell/gene therapy, biological production of molecules, and as in vitro models for research, toxicity testing, and drug development.
Patent CA-2476311-A1 (CA)
Title: Reduced-emissions combustion utilizing multiple-component metallic combustion catalyst
Inventor: VALENTINE JAMES M
IPC: C10L10/14
Filed: 2003-02-03
Abstract: Residual fuels, as well as lighter distillate fuels, are combusted with greater efficiency by utilizing low concentrations of specific bimetallic or trimetallic fuel-borne catalysts. The catalysts reduce fouling of heat transfer surfaces by unburned carbon while limiting the amount of secondary additive ash which may itself cause overloading of particulate collector devices or emissions of toxic ultra fine particles when used in forms and quantities typically employed. By utilizing a fuel containing a fuel-soluble catalyst comprised of platinum and at least one additional metal comprising cerium and/or iron, production of pollutants of the type generated by incomplete combustion is reduced. Ultra low levels of nontoxic metal combustion catalysts are able to be employed for improved heat recovery and lower emissions of regulated pollutants.
Patent CA-2479867-A1 (CA)
Title: Berry harvester
Inventor: EMERSON ZANE
IPC: A01D46/00
Filed: 2004-09-01
Abstract: Apparatus for raking berries, particularly blueberries. The apparatus has a frame supported on wheels, a rake head, a berry conveyor, support for a berry box, and a side support for stacking additional empty berry boxes. The motor-driven apparatus provides independent operation of ground travel and berry collecting operation. The rakes maintain a constant orientation relative to the vertical throughout the rotation of the rake head.
Patent CA-2483540-A1 (CA)
Title: Apparatus and method for making confectionery on a stick
Inventor: WRAY MARTYN THOMAS
IPC: A23G7/00
Filed: 2003-04-17
Abstract: Apparatus (1) and method for moulding lollipops, the apparatus comprising stick receiving means (6) and a mould forming surface (3) of a mould (15), t he stick receiving means being mounted for pivotal movement relative to the mou ld forming surface through substantially ninety degrees. In use the apparatus i s passed around a circuit (34) and engagement between the apparatus and a cam track (35) is such that a stick held by the stick receiving means is pivoted through substantially ninety degrees into the mould so that confectionery material can be poured into the mould and around the stick. As the apparatus further progresses around the circuit the formed lollipop is pivoted out of the mould for release from the stick receiving means.
Patent CA-2485309-A1 (CA)
Title: Boundary scan element and communication device made by using the same
Inventor: NAGOYA MITSUGU
IPC: G01R31/28
Filed: 1998-05-29
Abstract: There are provided a boundary scan element including a plurality of input-terminal-side boundary cells connected in series and assigned individually to respective input terminals, a plurality of output-terminal-side boundary cells connected in series and assigned individually to respective output terminals, a TAP circuit for controlling input and output of data to or from the input-terminal-side and output-terminal-side boundary cells, a TDI terminal for inputting serial data to be provided to the boundary cells, a TDO terminal for outputting data from the boundary cells as serial data, a TCK terminal to which a clock signal is input, and a TMS terminal to which a mode signal is input to switch an operation mode of the TAP circuit, characterized in that the input-terminal-side boundary cells and the output-terminal-side boundary cells are connected in parallel between the TDI terminal and the TDO terminal; and a communication system using the same.
Patent CA-2487597-A1 (CA)
Inventor: LEVEY MICHAEL ERNEST
IPC: A61K31/13
Filed: 2003-06-02
Abstract: A method of increasing the sensitivity of a bacterial strain to a cell-wall active antimicrobial agent, to which the bacterial strain or a progenitor strain from which the bacterial strain has evolved is sensitive is described.  The method comprises the step of exposing said bacterial strain to a transforming agent having the following formula (I):~ where moieties R1, and R2 are each independently selected from alkyl, alkyloxy, alkyloxycarbonyl, alkylcarbonyloxy, alkenyl, alkenyloxy, alkenyloxycarbonyl, alkenylcarbonyloxy, alkynyl, alkynyloxy: alkynyloxycarbonyl, alkynylcarbonyloxy, each of which may be substituted or unsubstituted, straight chain or branched or cyclic, aryl, aryloxy, aryloxycarbonyl, arylcarbonyloxy, each of which may be substituted or unsubstituted and cabamoyl, moiety R3 is selected from alkyl, alkyloxy, alkylcarbonyloxy, alkenyl, alkenyloxy, alkenylcarbonyloxy, alkynyl, alkynyloxy, alkynylcarbonyloxy, each of which may be substituted o unsubstituted, straight chain or branched or cyclic, aryl, aryloxy, arylcarbonyloxy, each of which may be substituted or unsubstituted, and carboxyl. other than R1, R2, and R3 are not all H, and Y is selected from a natural amino acid side chain. The use of an agent having the above formula in the manufacture of a medicament for increasing the sensitivity of a bacterial strain infecting, colonising or being carried by a patient, to an cell-wall active antimicrobial agent is also disclosed.
Patent CA-2487598-A1 (CA)
Inventor: CANHAM LEIGH TREVOR
IPC: A61L27/00
Filed: 2003-05-29
Abstract: A process for preparing an orthopaedic scaffold, or other solid body, said process comprising forming shaped blocks of a bioactive material comprising silicon, treating one or more selected surfaces of said blocks such that they will adhere to a similarly treated surface of a similar block, and self-assembly of a scaffold comprising two or more of said blocks under conditions in which the treated surfaces will bind together, and thereafter recovering the assembled structure. Products including orthopaedic scaffolds obtained using this process are also provided.
Patent CA-2487997-A1 (CA)
Title: Multideck shuffler with jam recovery and display
Inventor: KUKUCZKA NICK W
IPC: A63F1/12
Filed: 1995-07-28
Abstract: The present invention provides a machine for shuffling multiple decks of playing card including a first vertically extending magazine for holding a stack of unshuffled playing cards, and second and third vertically extending magazines each for holding a stack of cards, the second and third magazines being horizontally spaced from and adjacent to the first magazine. A first card mover is at the top of the first magazine for moving cards from the top of the stack of cards in the first magazine to the second and third magazines to cut the stack of unshuffled playing cards into two unshuffled stacks. Second and third card movers are at the top of the second and third magazines, respectively, for randomly moving cards from the top of the stack of cards in the second and third magazines, respectively, back to the first magazine to form a stack of shuffled cards.
Patent CA-2489559-A1 (CA)
Inventor: SAVA ALEX
IPC: A01N63/50
Filed: 2003-06-27
Abstract: The invention relates to methods and compositions for of treating water systems, particularly recirculating water systems contaminated by a biofilm containing sessile micro-organisms. The method includes the steps of forming a boron conditioned enzyme and contacting the biofilm with said boron conditioned enzyme, thereby planktonising the micro-organisms The boron conditioned enzyme retains a level of activity at least 40 % of the initial activity of the unconditioned enzyme for at least two hours after contacting the biofilm, either in the presence or absence of a biocide or corrosion inhibitor which would normally deactivate the enzyme. In preferred embodimen ts a biocide is added with the conditioned enzyme. The method and compositions are also applicable to remediation of tepid water systems in which biofilm m ay harbour pathogens such as sessile Legionella.
Patent CA-2490270-A1 (CA)
Title: Outside vehicle door handle
Inventor: STIGLICH DEEANNA
IPC: E05B65/20
Filed: 2003-06-27
Abstract: A handle assembly unlatches a door latch to open a door of a motor vehicle.  The handle assembly includes a housing (32) secured to the door. The housing (32) defines a well (38). A handle (56) is pivotally secured to the housing (32) for movement between a rest position and actuating positions into and out of the well (38). The handle assembly also includes a bell crank (76) that is pivotally mounted to the housing (32) and operatively engaged with the handle (56). In addition, the handle assembly includes a release lever (78) that is pivotally mounted to the housing (32) and selectively coupled to the bell crank (76). The release lever (78) is operatively connected to the door latch.  Movement of the handle (56) in either direction from its rest position pivots the bell crank (76) and the release lever (78) together relative to the housing (32) to unlatch the door.
Patent CA-2490814-A1 (CA)
Inventor: MOORE JERRY
IPC: A63H33/22
Filed: 2003-06-27
Abstract: A recreational or competitive flying disc (100) includes an illumination system employing an array of flexible optical fibers (118) to distribute the light of a single light emitting diode (LED)(116) from the rotational center of the disc (100) to its outside periphery. A small water-resistant compartment (114) centered on the underside of the disc houses the LED (116) , battery, and the illumination control. The leads (120, 122) of the LED (116) also serve as the contacts of the battery (142). One end of each of the optical fibers (118) is embedded in the LED (116), and the other end extends radially from the central housing (114) on the underside surface of the disc (100) to the rim of the disc. The flying disc (100) is illuminated without altering the aerodynamic properties of the disc (100).
Patent CA-2491904-A1 (CA)
Title: Targeted marketing system
Inventor: YOUNGMAN ROY D
IPC: G06Q30/00
Filed: 2003-07-08
Abstract: A device (200) and computer implemented method provide an interactive session with a customer in a retail environment in which a presentation is customized to the unique interests of that customer.
Patent CA-2493235-A1 (CA)
Title: Mould core of an injection moulding tool
Inventor: PLASS WERNER
IPC: A62B3/00
Filed: 2003-05-20
Abstract: The invention relates to a mould core (1) of an injection moulding tool for injection moulding preforms in plastic. The mould core (1) consists of a hollow sleeve, closed at one end and having a central axis, an outer surface (3), an inner surface (4) and a hollow cooling tube, positioned in the mould core (1) at a distance from the inner surface (4) of said core and connected to coolant supply conduits and coolant drainage conduits. The aim of the invention is to increase the cooling effect of the mould core (1) in relatio n to previously used mould cores. To achieve this, the cooling tube extends coaxially in relation to the mould core (1) over approximately the entire length of the latter and is provided with an outlet opening (9) on the outfl ow side and cooling grooves (11) are configured in the inner surface of the mou ld core (1), extending approximately crosswise to the central axis (2).
Patent CA-2495540-A1 (CA)
Title: Combined heater and pump
Inventor: STEINHARDT MICHAEL D
IPC: H02K9/04
Filed: 1995-12-19
Abstract: A compact combined heater and pump is disclosed. There is a pump housing forming an internal pump chamber, the housing having both an inlet and an outlet and an opening therethrough. A drive shaft is rotatably mounted in the opening and is driven by a motor located outside the chamber.      An impeller is mounted on the drive shaft within the housing and a heater is sandwiched in the chamber between the motor and impeller. Rotation of the shaft can draw liquid in from the inlet, past the heater and through the outlet. A cooling fan attached to the shaft for rotation therewith draws cooling air over control circuitry and then forces the air over the motor.
Patent CA-2501540-A1 (CA)
Title: Procedes et compositions pour fournir de la glutamine
Inventor: RUEDA RICARDO
IPC: A23L1/305
Filed: 2002-10-08
Abstract: La présente invention concerne des procédés et des compositions pour fournir à un être humain un complément de glutamine par administration orale d'une quantité efficace de N-acétyl-L-glutamine ou d'un sel de celle-ci acceptable d'un point de vue nutritionnel. La N-acétyl-L-glutamine ou son sel acceptable d'un point de vue nutritionnel peut être incorporé(e) à une composition liquide qui est compatible avec la consommation humaine. Des exemples de compositions appropriées comprennent des solutions aqueuses telles que celles utilisées en tant solutions de réhydratation à administration par voie orale et formules nutritionnelles liquides (y compris les formules à administration par voie entérique, les formules à administration par voie orale, les formules pour adultes, les formules pour enfants et les formules pour bébés). La quantité de N-acétyl-L-glutamine ou de sel de celle-ci acceptable d'un point de vue nutritionnel peut varier dans une large mesure mais ces compositions contiennent de manière générale suffisamment de N-acétyl-L-glutamine ou de sel de celle-ci acceptable d'un point de vue nutritionnel, pour fournir au moins un total de 140 mg de glutamine par kg de masse corporelle par jour.
Patent CA-2505286-A1 (CA)
Inventor: RAFFIN CATHERINE
IPC: C07D213/30
Filed: 2003-11-18
Abstract: L'invention concerne de nouveaux composés représentés par la formule générale (I), un procédé destiné à la préparation de ces composés et l'utilisation de ces composés dans des compositions pharmaceutiques destinées à la médecine humaine et vétérinaire ou bien dans des compositions cosmétiques.
Patent CA-2508247-A1 (CA)
Inventor: THOMPSON TODD
IPC: A61F2/82
Filed: 2003-12-23
Abstract: The present invention is directed to an implantable vascular prosthesis configured for use in a wide range of applications, such as treating aneurysms, maintaining patency in a vessel, and allowing for the controlled delivery of therapeutic agents to a vessel wall. The prosthesis comprises one or more helical sections coupled to one or more anchoring sections having a generally zig-zag or cell-like configuration. The prosthesis is configured to conform to a vessel wall without substantially remodeling the vessel, and further is configured to be precisely deployed in a vessel without shifting or foreshortening during deployment.
Patent CA-2512840-A1 (CA)
Title: Ensembles montes pour avion, roues et pneumatiques
Inventor: MONNERIE CHRISTIAN
IPC: B60C19/00
Filed: 2004-01-15
Abstract: L'invention concerne les ensembles montés pour avion et les roues et les pneumatiques qui les constituent. Les ensembles montés pour avion concernés par l'invention se caractérisent notamment par la combinaison de pression de gonflage supérieure à 9 bars et d'une flèche relative du pneumatique supérieure à 30%, la roue comportant une jante de réception du pneumatique et plus spécifiquement des sièges recevant les bourrelets dudit pneumatique. Selon l'invention, la jante comporte une fonctionnalité base creuse et est avantageusement de type monobloc.
Patent CA-2514950-A1 (CA)
Title: Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
Inventor: CARGILL MICHELLE
IPC: C12Q1/68
Filed: 2004-01-30
Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
Patent CA-2515781-A1 (CA)
Title: Vehicle seating system with improved vibration isolation
Inventor: HARDIN GEORGE THOMAS
IPC: B60N2/50
Filed: 2003-02-19
Abstract: A vehicle seating system includes a top frame for mounting to a vehicle seat.  A bottom frame is provided for mounting to the vehicle and a middle frame or linking system movably mounts the top frame to the bottom frame. The middle frame includes two pair of scissor arms with rollers at the ends of the scissor arms. The top frame has four corners with roller tracks at each corner. The bottom frame also has four corners with roller tracks at each corner. Included among the roller tracks of the top and bottom frames is a single pair of curvilinear tracks a pair of pivotal connecting tracks and two pair of linear tracks. A regulator system is also disclosed to regulate the amount of fore and aft travel of the top frame.
Patent CA-2518557-A1 (CA)
Title: Methods for producing macromolecule identifying polymers
Inventor: MINOURA NORIHIKO
IPC: C08F4/04
Filed: 2004-03-05
Abstract: A process for producing a macromolecule-identifying polymer which comprises: a step in which a starting-material monomer is polymerized in an aqueous solution in the presence of a macromolecule, crosslinking agent, and free-radical polymerization initiator to obtain a polymer having the macromolecule inside; and a step in which the macromolecule is removed from the macromolecule-containing polymer to obtain a macromolecule-identifying polymer having a template having the shape of the molecule of the macromolecule. The process is characterized in that the crosslinking agent has a solubility in 25~C water of 100 mass % or higher.
Patent CA-2521189-A1 (CA)
Title: Lysophosphatidic acid analogs and inhibition of neointima formation
Inventor: ZHANG CHUNXIANG
IPC: A61K31/00
Filed: 2004-04-09
Abstract: The phospholipid growth factor lysophosphatidic acids (LPAs) containing unsaturated fatty acids (18:1, 18:2 and 20:4) and fatty alcohols containing hydrocarbon chains with more than 4 carbons were capable of inducing a rapid formation of neointima, an initial step in the development of atherosclerotic plaque. LPAs with saturated fatty acids did not induce neointima formation. A  Peroxisome Proliferator-Activated Receptors gamma (PPAR.gamma.)-specific agonist Rosiglitasone also induced a profound formation of neointima. GW9662, a selective and irreversible antagonist of PPAR.gamma., abolished LPA- and Rosiglitazone-induced neointima formation, indicating that LPA-induced neointima formation requires the activation of PPAR.gamma.. These data suggest that LPA analogs that bind to but do not activate downstream signaling of PPAR.gamma. or antagonists of PPAR.gamma. that inhibit PPARy signaling would be useful in the prevention and/or treatment of neointima formation and atherosclerosis.
Patent CA-2521372-A1 (CA)
Title: Coolant system for fuel processor
Inventor: DESHPANDE VIJAY A
IPC: H01M8/12
Filed: 2004-03-30
Abstract: A coolant subsystem for use in a fuel processor and a method for its operation are disclosed. In accordance with a first aspect, the coolant subsystem is separate from the feed to the processor reactor and is capable of circulating a coolant through the processor reactor. In accordance with a second aspect, the constituent elements of the fuel processor are housed in a cabinet, and the coolant subsystem is capable of cooling both the processor reactor and the interior of the cabinet. In various alternatives, the fuel processor can be employed to reform a fuel for a fuel cell power plant and/or may be used to provide thermal control for unrelated mechanical systems.
Patent CA-2521652-A1 (CA)
Title: Supported metallocene catalysts
Inventor: KERR MARGARET
IPC: B01J31/00
Filed: 2004-04-07
Abstract: Supported metallocene catalysts and processes for the use of such catalysts in isotactic polymerization of a C3+ ethylenically unsaturated monomer. The supported catalysts comprise a particulate silica support, an alkyl alumoxane component, and a metallocene catalyst component. The support has an average particle size of 10-50 microns, a surface area of 200-800 m2/g and a pore volume of 0.9-2.1 milliliters per gram (ml/g). alumoxane is incorporated onto the support to provide a weight ratio of alumoxane to silica of at least 0.8:1. The metallocene is present in an amount of at least 1 weight percent of the silica and the alumoxane and is of the formula B(CpRaRb)(Fl~)MQ2 in which Fl~ is an unsubstituted fluorenyl group or a fluorenyl group symmetrically substituted at the 3 and 6 positions, B is a structural bridge between Cp and Fl~, Ra is a bulky substituent in a distal position, Rb is a less bulky substituent in a distal position, Rb is a less bulky substituent proximal to the bridge and non-vicinal to the distal substituent, M is a Group IVB  transition metal or vanadium, and Q is a halogen or a C1-C4 alkyl group.
Patent CA-2522166-A1 (CA)
Title: Lambda integrase mutein for use in recombination
Inventor: FLEMING ELENA
IPC: C12N9/22
Filed: 2002-05-30
Abstract: Provided is a lambda integrase mutein for use in recombination. This mutein finds utility, for example in application to artificial chromosomes, including ACes, that have been engineered to contain available sites for site-specific, recombination-directed integration of DNA of interest as provided herein. These artificial chromosomes permit tractable, efficient, rational engineering of the chromosome.