baber/WOPTO huggingface dataset:
Patent CA-2068863-A1 (CA)
Title: Particle-mediated transformation of animal tissue cells
Inventor: JOHNSTON STEPHEN A
IPC: C12N15/87
Filed: 1990-11-13
Abstract: A method of transferring a gene to vertebrate cells is disclosed. The method comprises the steps of: (a) providing microprojectiles, the microprojectiles carrying polynucleic acid sequences, the sequences comprising, in the 5' to 3' direction, a regulatory sequence operable in the tissue cells and a gene positioned downstream of the regulatory sequence and under the transcriptional control thereof; and (b) accelerating the microprojectiles at the cells, with the microprojectiles contacting the cells at a speed sufficient to penetrate the cells and deposit the polynucleic acid sequences therein. Preferably, the target cells reside in situ in the animal subject when they are transformed.  Preferred target cells are dermis or hypodermis cells, and preferred genes for insertion into the target cells are genes which code for proteins or peptides which produce a physiological response in the animal subject.
Patent CA-2069682-A1 (CA)
Title: Clean dry facing needled composite
Inventor: DABI SHMUEL
IPC: D04H18/02
Filed: 1992-05-27
Abstract: Novel facing materials and methods for their manufacture are provided by this invention. The facing material includes at least a fibrous top layer for engaging body fluid and a generally opaque middle layer.      A portion of the facing material is disposed, preferably by piercing, through the generally opaque middle layer to establish a fluid path through the generally opaque middle layer. In the preferred embodiment, the facing material includes a bottom layer having a capillary structure for drawing the body fluid from the fibrous top layer. In this preferred embodiment, the fibrous top layer extends through the generally opaque middle layer to provide fluid communication between the fibrous top layer and the bottom layer. These composite structures provide a clean/dry facing material that has a comfort of a textile facing and the high opacity of apertured thermoplastic films.
Patent CA-2070033-A1 (CA)
Inventor: HUTCHISON WAYNE R
IPC: B60N2/38
Filed: 1992-05-29
Abstract: A seat assembly is provided for a lawn and garden tractor wherein a fuel tank is an integral component of the seat.  A plastic fuel tank is sandwiched between an inner and an outer seat shell to provide a fuel tank which is easily accessible for maintenance and/or replacement.  A fuel inlet is provided at the top portion of the seat back facilitating easy and convenient refueling of the tank.  The elevated position of the fuel tank provides a head of fuel for vehicles not equipped with fuel pumps, reducing the likelihood of starvation as the vehicle is operated on hillsides and inclines.
Patent CA-2073500-A1 (CA)
Title: Compositions and methods for detecting and modulating rna activity and gene expression
Inventor: COOK PHILLIP D
IPC: C12Q1/68
Filed: 1991-01-11
Abstract: This invention relates to materials and methods for detecting and modulating the activity of RNA. The invention generally relates to the field of "antisense"  compounds, compounds which are capable of specific hybridization with a nucleotide sequence of an RNA. In accordance with preferred embodiments, this invention is directed to the design, synthesis and application of oligonucleotides and to methods for achieving therapeutic treatment of disease, regulating gene expression in experimental systems, assaying for RNA and for RNA  products through the employment of antisense interactions with such RNA, diagnosing diseases, modulating the production of proteins and cleaving RNA in site specific fashions.   It is well known that most of the bodily states in mammals including most disease states, are effected by proteins. Such proteins, either acting directly or through their enzymatic functions, contribute in major proportion to many diseases in animals and man.  Classical therapeutics has generally focused upon interactions with such proteins in efforts to moderate
Patent CA-2074050-A1 (CA)
Title: Diclofenac sodium plaster
Inventor: OKUYAMA HIROHISA
IPC: A61K47/08
Filed: 1992-07-16
Abstract: A diclofenac sodium plaster has a backing material and a paste spread on the backing material.      The paste is composed of diclofenac sodium, a pene-tration enhancer composed of 1-menthol and propylene glycol, and a hydrophilic base composed principally of a water-soluble polymer.
Patent CA-2074915-A1 (CA)
Title: Method of manufacturing a cooking utensil
Inventor: FIGUERAS JAIME MAS
IPC: A47J27/00
Filed: 1992-07-29
Abstract: ABSTRACT OF THE DISCLOSURE      A method of manufacturing a cooking utensil comprising a round container for the food, the container comprising a base, a plate of heat-conducting material and a cap enclosing the plate. plate is inserted into the enclosing cap and leaves an annular flow space between it and a preformed collar on the cap.  The assembly of the container base, the plate and the cap is centered between the ram and die of a press and intermetallically bonded by single or multiple impulse pressure, so as to form the convex curvature of the cap bottom and to mold the rim of the cap collar around the vessel.  During impulse pressure, the plate is pressed by plastic deformation into the flow space, where it is intermetallically bonded to the cap bottom, the cap collar and the corresponding region of the container.  Use is made of a plate having a base member which is circular in plan view and has at least three centering projections on its rim, around its circular periphery.  The impulse pressure is guided so that the intermetallic bond is formed at the same time as the material of the plate base member and the material of the centering projections is flow-bonded, and during the subsequent plastic deformation, to plate material forms a uniform collar which is pressed into the rim region of the cap collar.
Patent CA-2077111-A1 (CA)
Title: Pesticides
Inventor: WALTER HARALD
IPC: C07D405/12
Filed: 1992-08-28
Abstract: Pesticides Abstract Compounds of the formula         (I), in which: one of the radicals R2, R3, R4, R5, R6 and R7 is a group of the formula   (Ia);     the other five of the radicals R2, R3, R4, R5, R6 and R7 independently of one another are hydrogen, halogen, C1-C8alkyl, halo-C1-C8alkyl, C1-C4alkoxy-C1-C4alkyl, C1-C8alkoxy, halo-C1-C8alkoxy, C1-C8alkylthio, halo-C1-C8alkylthio, cyano, nitro, phenyl, phenoxy or phenylthio, where the phenyl groups in phenyl, phenoxy and phenylthio are unsubstituted or substituted by one, two or three substituents; Y is an oxygen atom, a sulfur atom or a group of the formula NRI (Ib); in which R1 is hydrogen, C1-C8alkyl, C1-C8alkanoyl, C1-C8alkanesulfonyl, halo-C1-C8alkanesulfonyl, cyano-C1-C8alkanesulfonyl or phenylsulfonyl, whose phenyl group is unsubstituted or substituted by one or twosubstituents selected from the group comprising halogen, C1-C4alkyl, nitro and cyano; m is 0 or 1; and n is 0 or 1; and R8 to R20 have the meaning given herein, and, if appropriate, their tautomers, in each case in their free form or in salt form, can be used as agrochemical active ingredients.
Patent CA-2077972-A1 (CA)
Title: Collapsible, insulated storage cooler
Inventor: BOOK STEVEN C
IPC: A45F3/00
Filed: 1992-09-10
Abstract: ABSTRACT     An  improved   collapsible,  portable,   multiple   use insulated cooler  with  a  removable  interior  water  proof liner, carrying  strap,  straps  to  secure  the  cooler  to another surface   for  use in transporting and storing items and having  straps to secure the collapsed assembly together for easy  carrying when  not  filled.    The  sides  fo  the container have an outer casing material, insulating foam and reflective barrier.
Patent CA-2079214-A1 (CA)
Inventor: SCHWARTE STEPHAN
IPC: B05D7/00
Filed: 1991-03-14
Abstract: The invention relates to a process for the production of a multicoat coating in which an aqueous transparent topcoat composition containing a polyacrylate resin as binder is employed. The polyacrylate resin can be obtained by adding, either successively or alternately in part amounts, a mixture of a carboxyl-containing ethylenically unsaturated monomer (a1) and a monomer (a2) free from carboxyl groups and a mixture (b) consisting of (meth)acrylic acid esters which are free from carboxyl groups, of hydroxyl-containing ethylenically unsaturated monomers and, if appropriate, of other ethylenically unsaturated monomers to an organic solvent and carrying out a polymerization in the presence of a radical-forming initiator and, at the end of the polymerization, neutralizing the resultant polyacrylate resin and dispersing it in water. The type and amount of (a1), (a2) and (b) are chosen so that the polyacrylate resin has a hydroxyl value of 40 to 200, an acid value of 20 to 100 and a glass transition temperature (T g) of -40°C to +60°C.
Patent CA-2081069-A1 (CA)
Title: Stereoselective preparation of halophenyl alcohols
Inventor: PATEL RAMESH N
IPC: C12P17/12
Filed: 1992-10-21
Abstract: ABSTRACT          STEREOSELECTIVE PREPARATION OF HALOPHENYL ALCOHOLS      A process is described for selectively preparing a compound of the formula   wherein:      R1 is halogen; R2 is halogen, alkyl, cycloalkyl, aryl or  ; and R3 is hydrogen, alkyl, cycloalkyl, aryl, or         halogen;   wherein the process comprises treating the associated ketone with an oxido-reductase or a microorganism comprising an oxidoreductase. Compounds prepared by this process are useful antipsychotic agents or useful intermediates therefor.
Patent CA-2081470-A1 (CA)
Inventor: SMITH GEORGE A
IPC: C08L77/08
Filed: 1992-03-13
Abstract: Stable aqueous microdispersions of finely divided polyamide resin particles and methods for the manufacture thereof are provided. The properties of these microdispersions are achieved by the addition thereto of an effective amount of a co-surfactant such as a lower alkyl alcohol. The provided microdispersions can be drawn into films which will form clear, continuous films at ambient or near-ambient temperatures regardless of the softening point of the polyamide resin. Dispersions according to this invention find use in hot melt adhesives, coatings, inks, and the like.
Patent CA-2086457-A1 (CA)
Title: Peristaltic pumping apparatus having an improved misloaded iv tube detecting circuit
Inventor: HARA KEITA
IPC: G01L19/12
Filed: 1992-12-30
Abstract: ABSTRACT OF THE DISCLOSURE          A  peristaltic  pumping  apparatus  has  a  misloaded-tube detector.    The  detector  is  constituted  of  a  pair  of pressure  sensors  and  a  CPU.    The pressure  sensors  are located on both sides of a fluid propelling portion onto which an IV tube containing a solution is  loaded.   The detector  detects  a  tube  misloading  by  making  use  of pressure which is applied to one pressure sensor when the tube is displaced onto the pressure sensor and is forced against it by the closing of a door.  Each sensor consists of first and second electrodes spaced from each other, a pressure-resistive conductive element attached to the first electrode and spaced from the second electrode and capable of  connecting  thereto,  and a  resistor connected  to  the first  and  second  electrodes.    The  CPU  judges  from  a resistance value of the pressure sensor as to whether the tube  is  properly  loaded  or  misloaded  or  whether  the pressure sensor is in an operative state.
Patent CA-2087568-A1 (CA)
Title: Data input device
Inventor: GOOCH MICHAEL J
IPC: G06F3/0362
Filed: 1993-01-19
Abstract: ABSTRACT OF THE DISCLOSURE A data input device has a moveable element, for example,  a circular  knob.  This  is  moveable  in  two different directions, one of which can be circular and the other can be along the axis of the knob.  A display unit is preferably associated with the screen, so that rotation of the knob in a first direction causes a pointer to scroll through a menu on the screen.   Actuation of the knob in the second direction causes the different screens to be selected, or selected items on the screen to change their state.  It can be used as a sole input device for microprocessor-based devices.
Patent CA-2090351-A1 (CA)
Title: Methods and apparatus for removing debris from a well bore
Inventor: WILLIAMS ROBERT M
IPC: E21B7/00
Filed: 1993-02-25
Abstract: A well clean-out tool includes a cylindrical member in which a helical conveyor screw is arranged for vertical sliding movement relative to the cylindrical member. The tool is lowered into a well bore until the shoe contacts debris within the bore. At that time, the screw is caused to descend relative to the cylindrical member, whereupon a lower end of the screw projects slightly below a lower end of the cylindrical member, and a rotary coupling between the screw and the cylindrical member is released, and a spring is caused to store energy. Thereafter, the screw is rotated relative to the cylindrical member, while the spring presses the cylindrical member against the debris in order to resist rotation of the cylindrical member. The screw projects only slightly downwardly beyond the lower end of the cylindrical member, e.g., less than one inch, in order to convey debris upwardly within the cylindrical member.      At the end of a clean-out operation, the screw is raised back into the cylindrical member whereupon the rotary coupling is re-engaged in order to produce rotation of the cylindrical member as the tool is removed from the well bore.
Patent CA-2090463-A1 (CA)
Title: Isolation and characterization of a novel protease from streptomyces lividans
Inventor: LICHENSTEIN HENRI
IPC: C12N15/57
Filed: 1992-06-29
Abstract: The isolation and characterization of a novel polypeptide, designated Protease X, identified while screening for proteases exported into the media by Streptomyces lividans, is described. Also disclosed is the DNA sequence of the gene encoding this protein.  The polypeptide was found to have proteolytic activity on the substrate succinyl-ala-ala-pro-phe-pNitroanilide, also cleaved by chymotrypsin, subtilisin, and cathepsin G. In addition, methods for purifying the protease and raising antibodies against it are reported. Lastly, the generation of a S. lividans strain deficient in this proteolytic activity is reported. Such a strain may prove useful as a host for production of heterologous protein products.
Patent CA-2091682-A1 (CA)
Title: Systeme pour determiner la tension de vapeur d'un liquide
Inventor: REED DONALD B
IPC: G01L7/00
Filed: 1991-10-10
Abstract: La pression de vapeur réelle de compositions liquides, tout particulièrement de compositions à multi-constituants, est mesurée à l'aide d'un appareil (14) comportant un piston et un cylindre qui définissent une chambre de dilatation (84), dans laquelle un échantillon de liquide est piégé. La chambre (84) est dilatée en étapes multiples et des mesures de pression et de température multiples sont faites lors de chaque dilatation pendant une certaine durée. Lors de chaque dilatation, la pression résultante est déterminée à partir de mesures multiples en utilisant la méthode d'approximation des moindres carrés et les valeurs de pression résultantes sont extrapolées pour déterminer la pression de vapeur réelle en utilisant une approximation linéaire. L'appareil est conçu de manière à permettre des mesures continues de la pression de vapeur d'un courant de traitement en échantillonnant un courant de fuite de liquide qui est maintenu à une température constante. L'appareil est monté horizontalement afin de minimiser la profondeur du liquide et d'accroître la vitesse de formation de bulles durant la dilatation de la chambre.
Patent CA-2091701-A1 (CA)
Inventor: SKOULTCHI MARTIN M
IPC: C09J4/00
Filed: 1993-03-16
Abstract: ABSTRACT A two-part  initiator  system useful  in acrylic adhesive  compositions comprising in one part a stable organoboron amine complex and in the second part an aldehyde destabilizer or activator. This initiator is particularly useful in elastomeric  acrylic  adhesive  compositions  and  provides  room  temperature, relatively slow curing systems with good adhesive properties making them useful in applications where longer open times are required.
Patent CA-2092751-A1 (CA)
Title: Gas compressor
Inventor: BENNITT ROBERT A
IPC: F04B25/02
Filed: 1993-03-26
Abstract: A gas compressor for effecting a two-step compression of the admitted gas, according to which a straight cylinder, clamped between end headers, confines valve assemblies wholly therewithin, and has a cylindrical sleeve set within one half length of the cylinder.
Patent CA-2098990-A1 (CA)
Title: Resin composition and a multi-layer laminate
Inventor: TSUTSUMI KATSUAKI
IPC: C08L77/06
Filed: 1992-11-24
Abstract: ABSTRACT A resin composition comprising (A) an ethylenic multi-component copolymer (an ethylene-maleic anhydride-methyl methacrylate ternary copolymer or the like) and at least one component selected from the group consisting of (B) a polyolefinic resin (a low density polyethylene or the like), (C) a metal salt of an organic carboxylic acid (an ionomer or the like) and (D) a copolymerized nylon (a nylon 6/66/12 copolymer or the like) and a multi-layer laminate having the resin composition described above as the adhesive layer are disclosed. This resin composition is a hot melt-type adhesive resin composition and has an excellent adhesive property to a wide range of base materials. Particularly, the resin composition comprising (B) or (C) is favorable for production of multi-layer laminates used for interior materials of automobiles and the like. The resin composition comprising (D) has an excellent adhesive property to the base materials to which sufficient adhesive property could not be obtained before.
Patent CA-2099860-A1 (CA)
Title: Aqueous coating composition and its use for coating substrates
Inventor: DHEIN ROLF
IPC: B05D7/02
Filed: 1993-07-05
Abstract: AN AQUEOUS COATING COMPOSITION AND    ITS USE FOR COATING SUBSTRATES                 ABSTRACT OF THE DISCLOSURE    The present invention relates to aqueous coating compositions containing an aqueous solution and/or dispersion of a)   a polyacrylate component which contains at least one copolymer having carboxylic and/or sulphonic acid groups which may be at least partially present in salt form, is based on the reaction product of olefinically unsaturated monomers and has an acid number of 30 to 240 mg KOH/g, a hydroxyl number of O to 180 mg KOH/g, and a molecular weight (Mn) of 500 to 50,000, b)   an epoxide component which contains b1)  at least one aliphatic or cycloaliphatic epoxy resin having an average of at least 2 epoxide groups per molecule and containing 0.2 to 2.0 equivalents of epoxide per 100 g of resin and b2)  up to 20 wt.%, based on the weight of b1), of at least one aliphatic monoepoxide with 7 to 25 carbon atoms, c)   up to 10 wt.%, based on the total weight of components a) to e), of one or more organic, water-miscible solvents, d)   up to 5 wt.%, based on the total weight of components a) to e), of one or more external emulsifiers and e)   optionally other known coatings additives, wherein the equivalent ratio of unneutralized acid groups of component a) to epoxide groups of component b) is 1:0.5 to 1:3.      The present invention also relates to the use of these coating compositions for the production of coatings for curing at 5 to 140°C on any desired substrates.
Patent CA-2103434-A1 (CA)
Title: Mounting arrangement for a single shaft combined cycle system
Inventor: KNUIJT HANS
IPC: F01K23/16
Filed: 1993-11-18
Abstract: MOUNTING ARRANGEMENT FOR A SINGLE     SHAFT COMBINED CYCLE SYSTEM               ABSTRACT             A power generation system comprising a gas turbine, a steam turbine and a generator are mounted on a foundation in substantial axial alignment and connected by a single shaft.  A thrust bearing is located on the shaft in one of the gas turbine and steam turbine.  Whichever of the gas turbine and steam turbine contains the thrust bearing is flexibly secured to the foundation, and the other of the gas turbine and the steam turbine, as well as the generator, are rigidly secured to the foundation.  A pair of rigid tie rods also extend between the steam and gas turbines, parallel to the shaft, to maintain a predetermined axial distance between the turbines, while allowing relative movement in a plane perpendicular to the shaft.
Patent CA-2104948-A1 (CA)
Title: Hermaphroditic gel closure
Inventor: JERVIS JAMES E
IPC: G02B6/44
Filed: 1992-03-13
Abstract: A hermaphroditic enclosure especially adapted to gel seal an elongate substrate and particularly a coaxial cable splice is described.
Patent CA-2107808-A1 (CA)
Inventor: SUGIMOTO TOSHIYA
IPC: C09D5/24
Filed: 1993-10-06
Abstract: An electrically conductive composition of the invention comprises 100 parts by weight of a (meth)acrylate compound possessing at least two (meth)acryloyl groups, 1 to 100 parts by weight of an anilinic electrically conductive polymer, and 0.1 to 20 parts by weight of a photopolymerization initiator sensitized by active rays. This electrically conductive composition may also comprise an unsaturated compound possessing any one group selected from the group consisting of a phosphoric acid group, a sulfonic acid group and a carboxyl group. Between the surface of a form to be coated and the coating layer made of the electrically conductive composition formed thereon, an inorganic electrically conductive layer composed of the tin oxide powder containing antimony with mean particle size of 0.01 to 0.4 µm, or the barium sulfate powder coated with tin oxide containing antimony with mean particle size of 0.01 to 2 µm, and a synthetic resin may be provided.
Patent CA-2109425-A1 (CA)
Title: Nouveaux composes polycycliques aromatiques et leur utilisation en medecine humaine ou veterinaire et en cosmetique
Inventor: CHARPENTIER BRUNO
IPC: C07C233/65
Filed: 1992-05-04
Abstract: 2109425 9219583 PCTABS00160 Composés bicycliques aromatiques, caractérisés par le fait qu'ils répondent à la formule générale (I) dans laquelle: R1 représente notamment -H, -CH3, -CH2OH, -OH, -CHO, -CONH2, -COOH, -COOalkyle, -SH, -S-alkyle, etc..., R2 est H; R3 est H, aryle, aralkyle ou alkyle inférieur éventuellement substitué par un hydroxyle, un alcoxy inférieur ou un radical -CO-R12, R12 est notamment H, alkyle inférieur, hydroxyle, alcoxy inférieur, ou R2 et R3 pris ensemble forment avec le noyau benzénique un cycle naphtalénique; R4 est un alkyle linéaire ou ramifié ou non ayant de 1 à 15 atomes de carbone ou un radical cycloaliphatique, R5 représente notamment -(CH2)n-R13, -CH=CH-(CH2)n-R13, n étant 0 ou 1 à 6, R13 représentant -COR15, monohydroxyalkyle, polyhydroxyalkyle, alkyle inférieur époxydé ou -O-CO-R16, R15 représente notamment -OH, -Oalkyle, -Oaryle, R16 est notamment H, alkyle inférieur, aryle, ou aralkyle. R6 et R7 sont H, un halogène, alkyle inférieur ou -OR16, ainsi que les sels des composés de formule (I) pour lesquels R1 représente un groupement acide carboxylique, et les analogues chiraux desdits composés de formule (I).
Patent CA-2115539-A1 (CA)
Title: Detergent compositions containing lipase and terpene
Inventor: PANANDIKER RAJAN K
IPC: C11D3/386
Filed: 1992-08-17
Abstract: Laundry detergent compositions contain detersive surfactant, lipase, and terpene or terpenoid with a boiling point between about 120 ·C and 229 ·C.
Patent CA-2117444-A1 (CA)
Inventor: PETERSEN EDWARD R
IPC: B63B21/44
Filed: 1994-08-10
Abstract: The lightweight or twin-fluke anchor is the most frequently used type of anchor in service on commercial and pleasure boats today. The weakest part of this anchor is the crown assembly. When a force is applied to the shank, the shank bears against the crown plate of the crown assembly at a single point. The embodiment of prior art anchors causes a can-opener like shear stress at the joint between the crown plates and the spacer plates that can cause the anchor to fail. In this invention the problem is eliminated by adding a pair of stop plates to the crown assembly to limit the rotation of the shank. These stop plates engage the shank over a length and greatly strengthen the anchor, eliminating the above type of failure.