baber/WOPTO huggingface dataset:
Patent CA-3077530-A1 (CA)
Title: Ball toy
Inventor: HOLDEN EDWARD
IPC: A63H1/00
Filed: 2018-10-10
Abstract: A ball toy having a solid, resiliently flexible body is disclosed, The body is penetrated by a bore, wherein bearing means are mounted, defining a rotational axis of the body therein. The bore has a bore closure at each end, mechanical connection means connecting each closure to the bearing means. The body is able to spin on said axis relative to the closures, when the closures are held in a pinching manner by a user. The body is made of a thermoplastic rubber of selected hardness properties, giving it excellent bouncing performance, with unpredictability of bouncing direction resulting from the spinning of the body.
Patent CA-3077598-A1 (CA)
Inventor: RUDOLPH ERIC
IPC: B01J19/18
Filed: 2018-10-02
Abstract: This disclosure relates to reaction container systems providing for headspace- based condensation, coalescing devices, and other features.
Patent CA-3078941-A1 (CA)
Title: Low-temperature stable opioid antagonist solutions
Inventor: LOUGHLIN RYAN
IPC: A61M15/08
Filed: 2018-09-28
Abstract: The present invention relates to pharmaceutical compositions comprising an opioid antagonist, PG, and an isotonicity agent. The pharmaceutical compositions are stable at temperatures as low as -5ºC or lower. Methods of using the pharmaceutical compositions are also disclosed.
Patent CA-3079530-A1 (CA)
Inventor: D'AMICO DANILO
IPC: A61K9/00
Filed: 2018-11-28
Abstract: A liquid pharmaceutical composition for oral administration comprising a complex of ketoprofen, dexketoprofen or their salts, a ß- cyclodextrin and a hydroxyalkylamine, having good palatability and improved chemico-physical and microbiological stability.
Patent CA-3079651-A1 (CA)
Inventor: BRYAN KILBEY E
IPC: A61F7/00
Filed: 2017-08-29
Abstract: The present invention comprises a heat transfer vest. The vest is configured to mount a plurality of heat transfer packs on its interior surface. In the preferred embodiments the appropriate portions of the interior surface are covered in a hook-compatible material, in these versions, the thermal transfer packs include one or more hook panels that are used to attach the packs to the interior surface.
Patent CA-3081321-A1 (CA)
Inventor: WU SAMUEL S
IPC: E21B21/08
Filed: 2018-10-30
Abstract: Système de pompe alternative comprenant une pompe alternative comportant une extrémité fluidique conçue pour recevoir un écoulement de fluide d'aspiration et décharger un écoulement de fluide de décharge, ainsi qu'un ensemble pompe intermédiaire d'aspiration raccordé à l'extrémité fluidique, cet ensemble pompe intermédiaire d'aspiration comprenant un venturi comportant un passage venturi, et un jet conçu pour projeter un fluide reçu à partir de la décharge de l'extrémité fluidique dans le passage venturi, l'ensemble pompe intermédiaire d'aspiration étant conçu de telle sorte que le jet de l'ensemble pompe intermédiaire d'aspiration projetant le fluide dans le passage venturi augmente la pression de l'écoulement de fluide d'aspiration.
Patent CA-3082769-A1 (CA)
Title: Polypeptides recombinants et leurs procedes d'utilisation
Inventor: CHEN YA-HUEI
IPC: A61K38/17
Filed: 2017-12-27
Abstract: La présente invention concerne des polypeptides recombinants, des acides nucléiques codant pour les polypeptides recombinants et des procédés d'utilisation de ces polypeptides et/ou acides nucléiques pour améliorer ou induire une réponse immunitaire chez un sujet en ayant besoin. La présente invention concerne également des méthodes de traitement d'un trouble prolifératif cellulaire, tel que le cancer, par administration des polypeptides et/ou des acides nucléiques selon l'invention à un sujet en ayant besoin.
Patent CA-3085483-A1 (CA)
Inventor: THURNER MARCO
IPC: C12N5/077
Filed: 2018-12-14
Abstract: La présente invention concerne des procédés d'obtention de cellules dérivées du muscle squelettique (SMDC), et l'utilisation de SMDC dans un procédé de prévention et/ou de traitement de neuromyopathies et/ou de myopathies, la neuromyopathie et/ou la myopathie étant l'incontinence, en particulier l'incontinence urinaire et/ou anale ou fécale.
Patent CA-3088031-A1 (CA)
Inventor: HOTCHKIN DARREN
IPC: E01F13/02
Filed: 2019-01-10
Abstract: Une barrière allongée (3) comprend une coque externe dans une section inférieure allongée de la barrière qui délimite une cavité (11) qui reçoit et contient un matériau de ballast durcissable versable lors de la fabrication de la barrière. La barrière comprend également un bloc solide (15) d'un matériau de ballast dans la cavité constitué du matériau de ballast durcissable versable.
Patent CA-3089268-A1 (CA)
Inventor: Geng Yuefei
IPC: A61P9/04
Filed: 2019-01-23
Abstract: La présente invention concerne des formes cristallines de mesaconine. Plus particulièrement, la présente invention concerne la forme cristalline A, la forme cristalline B et la forme cristalline C de mesaconine et un procédé de préparation correspondant. Le procédé comprend : la réalisation d'une cristallisation sur de mesaconine dans un solvant, et la réalisation d'un séchage pour obtenir une forme cristalline cible. Les formes cristallines de mesaconine selon la présente invention présentent une bonne solubilité, une bonne stabilité, une faible hygroscopicité, et une bonne reproductibilité, et sont appropriées pour un stockage à long terme et au développement de médicament.
Patent CA-3090142-A1 (CA)
Inventor: LI ZHEN
IPC: A61M16/00
Filed: 2020-08-16
Abstract: A system is disclosed for supplying a system and method for delivering a flow of electrons to an organism's airway for inhalation or mouth for ingestion. The system includes a pre-stage rectification and filtering module, a power conversion module, a post-stage rectification and filtering module, an output module, an over voltage protection module, a current-limiting protection module, and a pulse width controller.  Each of these modules and components is configured to deliver a suitable voltage and flow of electrons via the output module comprising a negative electrode that emits electrons into the air stream, which then enters the organism's air passages (e.g. nose).  Electrons emitted through the skin of the organism are captured by the output module's positive electrode. The flow of electrons from the system, to and through the organism and back to the system promotes cell metabolism and improved biological functioning of the organism.
Patent CA-3092497-A1 (CA)
Title: Novel rna-programmable endonuclease systems and uses thereof
Inventor: COHNEN ANDRE
IPC: C12N15/10
Filed: 2019-03-19
Abstract: Aspects of this invention, inter alia, relate to novel systems for targeting, editing or manipulating DNA in a cell, using novel synthetic RNA-guided nucleases (sRGNs). The sRGNs are derived from wildtype or parental small type II CRISPR Cas9 endonucleases.
Patent CA-3092506-A1 (CA)
Title: Manufacturing method for hen's egg improved in quality
Inventor: SENOO SATOKO
IPC: A23K50/75
Filed: 2020-09-09
Abstract: Provided is a method for producing hen's egg for which at least one quality among an effect for improving yolk color, an effect for improving eggshell strength, an effect for increasing an egg white height, an effect for increasing an eggshell thickness, an effect for increasing an egg weight, an effect for increasing a Haugh unit, an effect for increasing an egg production ratio, and an effect for reducing the generation ratio of an abnormal egg is improved. The method for producing hen's egg improved in quality includes feeding a solid-cultured product of filamentous bacteria blended with feedstuff of a hen or the solid-cultured product of the filamentous bacteria alone to a hen to improve quality of the hen's egg, in which at least one quality among improvement in yolk color, improvement in eggshell strength, increase in an egg white height, increase in an eggshell thickness, increase in an egg weight, increase in a Haugh unit, increase in an egg production ratio, and reduction in a generation ratio of an abnormal egg is improved for hen's egg that the hen ingesting the solid-cultured product of the filamentous bacteria produce.
Patent CA-3092828-A1 (CA)
Title: Compounds, compositions, and methods for suppressing toxic endoplasmic reticulum stress
Inventor: STOCKWELL BRENT R
IPC: C07D401/14
Filed: 2019-03-01
Abstract: The present invention provides, inter alia, a compound having the structure (I). Also provided are compositions containing a pharmaceutically acceptable carrier and one or more compounds according to the present invention. Further provided are methods for treating or ameliorating the effects of a disorder in a subject, methods of suppressing the toxicity of endoplasmic reticulum (ER) stress in a subject, methods of treating or ameliorating the effects of a disease involving axon degeneration in a subject, and methods for treating or ameliorating the effects of a neurodegenerative disease.
Patent CA-3094844-A1 (CA)
Inventor: STREULI DAVID C
IPC: A61K8/02
Filed: 2019-04-01
Abstract: L'invention concerne une composition de coiffure comprenant au moins un polygalactomannane modifié cationiquement ayant une masse moléculaire située dans une plage allant d'environ 40 à environ 1 100 kDa et au moins un ingrédient cosmétique. L'invention concerne également un procédé d'utilisation de celle-ci et un processus de préparation de celle-ci.
Patent CA-3095931-A1 (CA)
Inventor: KAROL DANIEL S
IPC: A61M1/28
Filed: 2019-04-15
Abstract: A system including a pumping cassette having a first side including number of valve wells and second side having a fluid bus. Each side may be covered by a flexible membrane. A control surface having a number of valve well control stations actuatable with respect to the flexible membrane covering the first side of the cassette to open and close the valve wells when the cassette is mated against the control surface may be included. A pressure distribution assembly having a positive and negative pressure source and a number of pneumatic valves may be included. A controller configured to selectively actuate the number of pneumatic valves to apply pressure against the valve well control stations in a valve pumping sequence until a volume displaced through the fluid bus of the pumping cassette from a source to a destination is within a range of a target volume may be included.
Patent CA-3096972-A1 (CA)
Title: Tuyau souple de faible poids
Inventor: BLOCK ANDREW P
IPC: F16L11/08
Filed: 2019-04-25
Abstract: L'invention concerne un corps tubulaire d'un ensemble tuyau souple de jardin. Le corps tubulaire comprend un tube interne (44) comprenant une surface interne et une surface externe, la surface interne définissant un passage intérieur de l'ensemble tuyau souple de jardin. Le corps tubulaire comprend en outre un tube externe (48) comprenant une surface interne et une surface externe, la surface interne entourant la surface externe du tube interne. Le corps tubulaire comprend en outre une couche de renfort (52, 56) comprenant un motif hélicoïdal en spirale dans au moins une direction autour de la surface externe du tube externe. Le corps tubulaire comprend en outre un revêtement interne (60) comprenant une surface interne et une surface externe, la surface interne entourant la couche de renfort. Le corps tubulaire comprend en outre un revêtement externe (64) comprenant une surface interne et une surface externe, la surface interne entourant la surface externe du revêtement interne.
Patent CA-3098497-A1 (CA)
Inventor: FRANKEL STANLEY R
IPC: A61K31/519
Filed: 2019-04-30
Abstract: L'invention concerne des polythérapies faisant intervenir des immunothérapies, par exemple, une thérapie par lymphocytes T à récepteur antigénique chimérique (CAR), et l'utilisation d'un inhibiteur de kinase, par exemple, un inhibiteur de BTK/lTK, par exemple l'ibrutinib, pour traiter des patients ayant des cancers tels que certaines malignités des lymphocytes B, et des procédés, des compositions, des utilisations et des articles manufacturés apparentés. La thérapie par lymphocytes T CAR comprend des cellules qui expriment des récepteurs recombinants tels que CARS anti-CD19. Dans certains modes de réalisation, la malignité des lymphocytes B est un lymphome non hodgkinien (LNH), tel qu'un LNH récidivant ou réfractaire ou un sous-type spécifique de LNH.
Patent CA-3100216-A1 (CA)
Inventor: WHALEN KERRY
IPC: A61K31/454
Filed: 2019-05-31
Abstract: D'une manière générale, l'invention concerne une polythérapie pour le traitement du cancer comprenant l'administration d'au moins deux agents thérapeutiques distincts. L'invention concerne également des constituants de la polythérapie et des méthodes d'utilisation de la polythérapie.
Patent CA-3104830-A1 (CA)
Inventor: COHEN RICHARD B
IPC: B65G1/137
Filed: 2019-06-26
Abstract: A product order fulfillment system including a multi-level transport system and a lifting transport system. Each level of the multi-level transport system having a corresponding independent asynchronous level transport system separate and distinct from the asynchronous level transport system corresponding to each other level of the multi-level transport system. Each independent lift axis of the lifting transport system being configured to independently hold at least one case and being communicably coupled to each asynchronous level transport system so as to provide for exchange of the at least one case between each asynchronous level transport system and each independent lift axis. Each independent lift axis is communicably coupled to each other independent lift axis of the more than one lift axis and forms a common output of mixed cases so as to create an ordered sequence of mixed cases in accordance to a predetermined case out ordered sequence.
Patent CA-3104966-A1 (CA)
Title: Process for producing beta-lactoglobulin isolates and related methods and uses
Inventor: LAURIDSEN KASPER BOGELUND
IPC: A23J1/20
Filed: 2019-06-26
Abstract: The present invention pertains to novel beta-lactoglobulin (BLG) isolates as well as to a method of producing such isolates and to uses of the powders, e.g. in beverage applications.
Patent CA-3105786-A1 (CA)
Inventor: PUCCI SABRINA
IPC: A61K31/40
Filed: 2019-07-04
Abstract: The following invention relates to (R)-4-(1-(1-(4-(trifluoromethyl)benzyl) pyrrodiline- 2-carboxamide) cyclopropyl benzoic acid (Compound 1) or a salt thereof. Advantageous methods for obtaining the Compound 1 are also described, as well as pharmaceutical compositions containing it. (R)-4-(1-(1-(4- (trifluoromethyl)benzyl)pyrrodiline-2-carboxamide) cyclopropyl benzoic acid (Compound 1) or a pharmaceutically acceptable salt thereof is described for use as an EP4 receptor antagonist in the treatment of a pathology that involves the activities of prostaglandin E2 (PGE2) in its pathogenesis.
Patent CA-3109822-A1 (CA)
Title: Microfluidic module for co-encapsulation in droplets
Inventor: GILET TRISTAN
IPC: B01J13/04
Filed: 2019-07-04
Abstract: Microfluidic module (100) for co-encapsulation in droplets of two populations of particles, comprising a first (1) and a second (2) modules for sorting said two populations, said modules (1, 2) having their first outlets (12, 22) comprising first obstructive valves (121, 221) configured to at least partially obstruct said first outlets (12, 22), said first outlets (12, 22) being fluidly connected to: - a fusion module (3) comprising:  a fusion module means (30) for merging at least one droplet from the first droplet population and at least one droplet from the second droplet population into a merged droplet comprising said two population of particles, - a control unit (4) for controlling:  said first obstructive valves (121, 221) from information originating from a first (19) and second (29) module detection portion located upstream of said first outlets (12, 22).
Patent CA-3109891-A1 (CA)
Inventor: WU FRANK
IPC: A61P9/00
Filed: 2019-08-23
Abstract: La présente invention concerne un nouvel inhibiteur de dérivé de quinoléine, qui a une structure représentée par la formule générale suivante (I). Le composé selon la présente invention peut inhiber de manière sélective la famille TAM de tyrosine kinases/et CSF1R Kinase, et peut être utilisé pour le traitement et/ou la prévention de maladies induites par l'expression anormale de kinases de la famille TAM/et des récepteurs de CSF1R kinase et/ou de leurs ligands. En outre, le composé selon la présente invention peut être utilisé pour traiter et/ou prévenir des maladies associées provoquées par NTRK, plus particulièrement, ledit composé peut être utilisé pour le traitement et/ou la prévention de maladies associées à un médicament provoquées par des mutations NTRK. (I) Les définitions de chaque groupe sont telles que représentées dans la description.
Patent CA-3110443-A1 (CA)
Inventor: KOSTENICH GENADY
IPC: A61B5/00
Filed: 2019-08-27
Abstract: A system and method are presented for use in monitoring oxygenation in biological tissue. The system comprises a control unit being configured and operable to receive data indicative of light response from a region of the biological tissue being subjected to illumination and/or collection at two separate wavelengths in two selected wavelength ranges and processing the data by comparing data indicative of each selected wavelength range to determine an oxygenated/deoxygenated status of the biological tissue. The two wavelength ranges comprise a first wavelength range in which the absorbance of the deoxyhemoglobin within the tissue is higher than the oxyhemoglobin, and a second wavelength range in which the absorbance of the oxyhemoglobin within the tissue is higher than the deoxyhemoglobin or vice versa. The two wavelengths in said two wavelength ranges comprise first and second wavelengths satisfying a predetermined condition of a ratio between the absorbance of the deoxyhemoglobin and the oxyhemoglobin for each of the first and second identified wavelengths.
Patent CA-3115221-A1 (CA)
Title: Omnidirectional moving surface with motor drive
Inventor: CARMEIN DAVID
IPC: F16C19/20
Filed: 2019-10-02
Abstract: A motor driven omnidirectional treadmill that allows users to walk, jog, or run in any direct ion. When the treadmill is coupled with computer-generated immersive environments users can maneuver their way on-foot through 360-degree VR environments of infinite expanse and scope.
Patent CA-3115478-A1 (CA)
Inventor: KOGA JEFFREY
IPC: G09F19/18
Filed: 2021-04-16
Abstract: A vehicle includes an automated apparatus extending from the vehicle and a projection system.  The projection system includes a projector positioned on the vehicle. The projector is configured to operate to provide a projection onto a ground surface, the projection covering a zone. The automated apparatus is configured to operate within the zone.
Patent CA-3115651-A1 (CA)
Inventor: PRYOR STEVEN E
IPC: E04B1/24
Filed: 2019-10-09
Abstract: Une construction formée d'une colonne et d'une poutre est décrite, la poutre comprenant des bords tombés supérieurs et inférieurs raccordés à la colonne par un système de support latéral, et une toile entre les bords tombés supérieurs et inférieurs. Le système de support latéral peut comprendre un plateau monté sur la colonne comprenant une partie horizontale et une partie verticale, laquelle est fixée à la colonne. La poutre peut être contre-profilée aux bords supérieurs et inférieurs de la toile pour empêcher la liaison du bord tombé de la poutre avec le plateau monté sur colonne au moment de la rotation de la poutre par rapport à la colonne. L'invention concerne un système de support latéral construit pour offrir un degré élevé de dissipation d'énergie par atténuation hystérétique et grande rigidité de départ, de sorte que l'énergie soit dissipée des seuils de déplacement faibles dans une construction à charpente légère.
Patent CA-3115955-A1 (CA)
Title: A seal for a protrusion and method of use
Inventor: BRIGHAM GRAHAM
IPC: F16L5/10
Filed: 2021-04-21
Abstract: ABSTRACT A seal for a protrusion has a flexible lower flange and a flexible upper flange. An aperture extends through the flexible lower flange and the flexible upper flange. The aperture has a wall. The wall attaches the flexible lower flange to the flexible upper flange such that the flexible lower flange and the flexible upper flange are spaced from each other. A slit extends from an outer edge of the lower flange through the upper flange and the wall of the aperture such that the slit allows the lower flange and the upper flange to be slid over a protrusion such that the wall of the aperture encircles the protrusion and the lower flange and the upper flange return to their original shape. Date Recue/Date Received 2021-04-21
Patent CA-3117437-A1 (CA)
Inventor: AGARKHED AJIT MANOHAR
IPC: A61K8/34
Filed: 2019-10-28
Abstract: This invention relates to an antimicrobial composition, more particularly a personal care composition like a soap bar. It more particularly relates to a composition comprising an essential oil compound and a tetra hydroxy alkylene amine compound which interact synergistically to provide the desired result.
Patent CA-3119290-A1 (CA)
Inventor: USHER NORMAN
IPC: E03D3/00
Filed: 2019-11-12
Abstract: A system that uses a flushometer for residential toilets in which adjustments and additions are made in order to allow the flushometer to operate correctly. There is an immediate flush water assembly that provides enough water, under pressure to pas through the flushometer. Also, a check valve can be used to isolate the pressurized water stored for the flush so as to reduce effect on the residential plumbing system and to provide control over flush and recharge. Also, a reduced diameter supply piping portion allows for additional control.
Patent CA-3119346-A1 (CA)
Inventor: PENNER ANDREW
IPC: H04L29/06
Filed: 2019-11-18
Abstract: Systems and methods for applying an application layer policy to a transport layer security request are provided. A device, intermediary to one or more clients and one or more servers, can receive a transport layer security (TLS) request to establish a TLS connection between a client of the one or more clients and a server of the one or more servers. The TLS request can include an application layer request to a resource of the server. The device can apply an application layer policy to the application layer request of the TLS request. The device can determine, responsive to applying the application layer policy, whether to one of accept or reject at least the application layer request of the TLS request.
Patent CA-3122261-A1 (CA)
Inventor: HOPKINS SETH CABOT
IPC: A61P25/18
Filed: 2019-12-05
Abstract: La présente invention concerne des procédés de traitement de maladies ou de troubles neurologiques ou psychiatriques, tels que la schizophrénie. Le composé 1, ou un sel pharmaceutiquement acceptable de celui-ci, est un agent antipsychotique avec un mécanisme d'action non D2. Des événements indésirables associés à des agents antipsychotiques qui ciblent le récepteur D2 de la dopamine peuvent être réduits par le traitement de troubles avec le composé 1, ou un sel pharmaceutiquement acceptable de celui-ci.
Patent CA-3124061-A1 (CA)
Title: System and method for managing multiple transactional workflows
Inventor: HOUDE BRIGITTE
IPC: H04L12/16
Filed: 2021-07-08
Abstract: A system and method are provided for managing multiple transactional workflows. The method includes saving each transactional workflow with a unique identifier, mapping the unique identifier to an entity associated with the client device used to initiate the corresponding transactional workflow, providing a first option for the client device to retrieve from the server device details of the plurality of transactional workflows, and receiving a request at a later time to retrieve details of the plurality of transactional workflows. The method also includes performing an authentication process, using the predetermined identifying information to determine unique identifiers of the corresponding saved transactional workflows, providing a second option for the client device to resume one or more of the transactional workflows, and resuming the corresponding one or more transactional workflows. Each transactional workflow is saved in a format that permits the server device to execute and complete a binding outcome.