baber/WOPTO huggingface dataset:
Patent CA-2089563-C (CA)
Title: Oligonucleotide modulation of cell adhesion
Inventor: BENNETT CLARENCE FRANK
IPC: C12Q1/68
Filed: 1991-07-23
Granted: 2004-04-06
Abstract: Compositions and methods are provided for the treatment and diagnosis of diseases amenable to treatment through modulation of the synthesis or metabolism of intercellular adhesion molecules.  In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically hybridizable with nucleic acids encoding intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and endothelial leukocyte adhesion molecule-1. The oligonucleotide comprises nucleotide units sufficient in identity and number to effect said specific hybridization. In other preferred embodiments, the oligonucleotides are specifically hybridizable with a transcription initiation site, a translation initiation site, 5'-untranslated sequences, 3'-untranslated sequences, and intervening sequences. Methods of treating animals suffering from disease amenable to therapeutic intervention by modulating cell adhesion proteins with an oligonucleotide or oligonucleotide analog specifically hybridizable with RNA or DNA corresponding to one of the foregoing proteins are disclosed. Methods for treatment of diseases responding to modulation cell adhesion molecules are disclosed.
Patent CA-2093615-C (CA)
Title: Electric arc furnace dust as a raw material for brick
Inventor: FRAME SCOTT W
IPC: C04B33/13
Filed: 1993-04-07
Granted: 2004-07-06
Abstract: A process for producing brick involves calcining electric arc furnace dust and subsequently mixing the dust with a brick raw material prior to shaping the material into bricks and firing. The precalcination of the EAF dust greatly increases the bulk density of the dust and provides a brick having a much higher compressive strength when compared to bricks incorporating raw dust which has not been precalcined. Volatilized and recondensed heavy metals produced during the calcination process are collected and refined.      As a result of the separation and collection of the volatilized heavy metals during the calcination process, substantially no heavy metals are volatilized during the brick firing process.
Patent CA-2098856-C (CA)
Inventor: ENGEL DARRYL L
IPC: B66F3/12
Filed: 1993-06-21
Granted: 1999-01-19
Abstract: An  improved  open  end  construction  for  jacks  which provides for tabs which extend at right angles to the side surfaces of the channel members so as to allow pivot pins to be received in the open ends after which the tabs are bent so that they lie in the plane of the side surfaces of the channel members so as to lock the pivot pin in the ends of the channel assembly.   Also, partial flanges can be formed about the openings in the ends of the channel members so as to provide bearing surfaces for the pivot pins.
Patent CA-2101070-C (CA)
Inventor: MASTICO ROBERT A
IPC: C07K19/00
Filed: 1992-01-22
Granted: 2003-04-01
Abstract: A chimaeric protein, suitable for incorporation in a vaccine and capable of forming parts of a capsid assembly, comprises the amino acid sequence of the coat protein of phage MS-2, or a conservatively modified variant thereof, or sufficient of said sequence or variant to retain capsid-forming capability, which amino acid se-quence has been modified by insertion of a foreign epitope in the region correspond-ing to a protuberant protein hairpin in the capsid assembly as shown in the crystal structure of the intact phage.
Patent CA-2103148-C (CA)
Title: Determination of motifs of peptides on mhc molecules
Inventor: RAMMENSEE HANS-GEORG
IPC: C07K16/00
Filed: 1992-05-15
Granted: 2004-07-20
Abstract: The present invention concerns a method for the determination of allele-specific peptide motifs on molecules of the major histocompatibility complex (MHC) of classes I and II as well as the peptide motifs which are obtainable by the method according to the invention.      In addition the use of the peptide motifs according to the invention for the production of a diagnostic or therapeutic agent is disclosed.
Patent CA-2105681-C (CA)
Title: Low noise optical probe
Inventor: DIAB MOHAMED K
IPC: G01N21/17
Filed: 1992-03-05
Granted: 2003-07-08
Abstract: An optical probe (100) which is particularly suited to reduce noise in measruements taken on an easily compressible mate-rial, such as a finger, a toe, a forehead, an earlobe, or a lip. The probe includes a base (110) having an aperture (120) which leads to a chamber (122). The base is placed adjacent a portion of the material, the chamber being placed directly adjacent any easily compressible portion of the material. A photodetector (126) is located within the chamber and does not contact the material. A light emitting diode (LED) (130) is affixed to the material, opposite the photodetector and above the chamber. The material which is supported by the aperture and therefore rests above or has intruded into the chamber is inhibited from compression since no-thing comes in contact with this portion of the material, even when the material moves. Thus, light from the LED is directed through a stabilized portion of the material, such that the optical path length through which light travels is stabilized.
Patent CA-2108579-C (CA)
Inventor: ROTHSCHILD MAX F
IPC: C12N15/09
Filed: 1992-04-16
Granted: 2003-06-10
Abstract: Disclosed herein are genetic markers for pig litter size, methods for identifying such markers, and methods of screening pigs to determine those more likely to produce larger litters. The markers are based upon the presence or absence of polymor-phisms in the pig estrogen receptor gene. Preferably, the polymorphism is a restriction fragment length polymorphism (RFLP). A 4.3 kilobase fragment obtained by digesting pig genomic DNA with the restriction endonuclease Pvu II and detecting the frag-ments with a probe comprising a delectably labeled human estrogen receptor gene is associated with increased litter size.
Patent CA-2111958-C (CA)
Inventor: HASTINGS REED
IPC: G06F9/44
Filed: 1992-06-05
Granted: 2003-08-05
Abstract: An object code expansion program (5) inserts new instructions and data between preexisting instructions end data of en object code file (I); offsets are modified to reflex new positions of the preexisting instructions and data. For each item of preexisting object code (instruct-tion or data), the following steps are performed: making a new code block comprising any desired new instructions and the item, and storing it as new object code; tracking the location of the item and the new code block within the new object code; and tracking items that contain inter-item offset. Then, each inter-item offset is updated using the new location of the item or new code block, as re-quired. Finally, offsets in symbol tables and relocation structures are updated with the new location of the item.  This extension program is used to add instructions to ob-ject code files to monitor memory accesses of another pro-gram.
Patent CA-2116580-C (CA)
Title: Appliance for preparation of hot drinks
Inventor: LUESSI ANDRE
IPC: H02J3/00
Filed: 1993-07-01
Granted: 2000-11-07
Abstract: The device, especially a coffee machine, comprises three boilers (1, 2, 3) for heating water.  To this end, in each boiler there is a heating element (10, 11, 12) which can be switched on and off by a switch (20, 21, 22) in a control device (16). There is also a temperature probe (13, 14, 15) in each boiler to measure the hot water temperature.  In addition, the control device (16) has computing (17) and storage means (18, 19).  Predetermined reference temperatures for the water in the individual boilers and the maximum power supply available for the coffee machine can be stored in the storage means (18, 19).  The control device is laid out in such a way that, on the basis of the water temperature cycle in the individual boilers, heating power can be distributed to that boiler which needs it first owing to a certain priority.  At the same time, it is ensured that the coffee machine can draw no more heating power than is available.  This variable heating power allocation to the individual boilers thus makes it possible to dispense a large number of beverages even if the maximum available power is insufficient to supply all the heating elements at the same time.  The heating power is allocated in the device of the invention depending on the power supply and the power requirement of the individual boilers.
Patent CA-2121215-C (CA)
Inventor: VENAS KARL
IPC: B01F25/60
Filed: 1994-04-13
Granted: 2004-11-02
Abstract: Injection equipment for the supply of gas and/or particulate material in the form of powder, granules, chips or similar to a liquid, for example metal melt, comprising a rotation body (1) which is designed to be lowered down into the liquid and which is mounted on and driven via a shaft (2) of a drive unit (4,7). The material and/or gas is supplied to the liquid through the rotor via a coaxial bore in the shaft. The special feature of this equipment is that the rotation body has a cone-like or funnel-like design and is generally completely open at the bottom.
Patent CA-2126395-C (CA)
Title: Dispenser gun for viscous or semi-viscous products
Inventor: WOODRUFF KEITH F
IPC: B05C5/00
Filed: 1994-06-21
Granted: 2004-04-13
Abstract: A dispenser gun for selectively dispensing controlled quantities of viscous or semi-viscous materials, and in particular liquid pesticides or insecticides, employs a vacuum driven operating system for discharging and reloading the viscous or semi-viscous materials to be discharged. The dispenser gun is designed to create pressure differentials in adjoining chambers which, in conjunction with a cooperating valve system, enables the discharge of precisely metered quantities of material and prevents continued and undesired discharge or dripping from a discharge nozzle after a preselected quantity of material has been discharged from the dispenser gun. The handle of the device includes structure for pre-selecting one or more predetermined quanitites of material to be discharged from the dispenser in repeatable sequences. The dispenser gun also includes structure for removably receiving a replaceable reservoir of viscous or semi-viscous material to be discharged from the gun.
Patent CA-2135740-C (CA)
Inventor: OLSON DARWIN C
IPC: F16L55/115
Filed: 1994-11-14
Granted: 2006-06-06
Abstract: An assembly includes a quick connect cartridge which is inserted into a port of a valve or manifold in a pneumatic system for coupling external fluid lines of the system to the valve or manifold. The components of the quick connect cartridge and the O-ring seal are mounted on the tubular shank of a plug. The plug is used as a shipping pin and is also used to install the components into a port of the valve or manifold.      Normally, the plug is withdrawn from the port after the components are inserted in the port. If it is desired to keep the port closed after initial installation of the components, the plug may be retained in the port until it is time to connect the port. If it is desired to leave the port permanently closed, the plug remains in place. The plug can be an open plug allowing testing of the valve in which case a dust plug is provided for shipping purposes.
Patent CA-2142593-C (CA)
Title: Ramp-up lateral accelerator in a flat-article feed and shingling device
Inventor: RICCIARDI MARIO
IPC: B65H1/14
Filed: 1993-08-18
Granted: 1999-07-13
Abstract: A transport mechanism for transporting flat documents (5) placed therein on edge uses a horizontal conveyor belt (1) to convey stacks of documents on-edge in a first feeding direction. Tapered rollers (9) with a feeding direction perpendicular to that of the conveyor belt (1) are provided at the end of the conveyor for feeding the documents (5) in a direction perpendicular to the first feeding direction. The use of tapered rollers (9) allows a gradual, rather than sudden, perpendicular velocity to be imparted to the documents (5), thereby relieving strain on the roller drive mechanism, the rollers (9) themselves, and the documents (5) at high machine throughput speeds. The use of tapered rollers (9) also provides a shingled output of documents to a feeder (17), which allows a stripping station down-line from the feeder (17) to strip the documents (5) with fewer misfeeds and less strain.
Patent CA-2143350-C (CA)
Inventor: PORTWOOD GARY
IPC: E21B10/52
Filed: 1995-02-24
Granted: 1998-09-29
Abstract: A conical insert is disclosed having a cutting tip which includes a spherically shaped apex and a substantially conical surface therebelow. The trailing side of the cutting tip is convex as seen in a longitudinal section taken normal to the apex. The leading side of the cutting tip is either a straight line segment or is concave as seen in the longitudinal section taken normal to the apex.
Patent CA-2144574-C (CA)
Inventor: UTIGER MARC
IPC: B41K3/00
Filed: 1995-03-14
Granted: 2001-04-24
Abstract: An optical trigger is provided for use in a postage meter having a planar paper path.  A light source with controllable intensity is mounted above the paper path and shines toward the paper path.          A light sensor mounted above the paper path detects the reflected light if any.  A dark region is provided below the paper path.          More power is supplied to the light source when the sensor detects some light.  An actuator is coupled with the printing mechanism of the meter to actuate it for printing of postage.          When light is reflected from a mail piece, a timer is started, and when the timer reaches its programmed interval the actuator is actuated.  The interval is adjustable by a trimmer adjustment, and two preprogrammed intervals may be selected by a front-panel switch.
Patent CA-2148616-C (CA)
Inventor: BURGESS LAURENCE E
IPC: C07D/
Filed: 1993-09-17
Granted: 1998-02-03
Abstract: L'acide 4-chloro-2-thiophènecarboxylique est obtenu en formant un composé de formule (Ia), où R3 est un alkyle en C1-C6, un phényle ou un benzyle; en convertissant les composés en un composé de formule (IVa); et en éliminant le groupe silyle R3Si-. Le produit est utile comme intermédiaire pour la fabrication de produits pharmaceutiques.
Patent CA-2150743-C (CA)
Inventor: NELSON DWIGHT QUENTIN
IPC: G06F1/32
Filed: 1995-06-01
Granted: 2002-11-19
Abstract: A power saving method and apparatus while maintaining an operational or near-operational state for computer memory disk drives. A microprocessor implements microcode instructions to determine if a disk drive is inactive. This is done by checking a control unit through an interface to see if any files are currently opened or data is being transferred by the disk device. If no files are opened and/or no data transfers are occurring, the drive is considered inactive. If theinactive period continues for a period of time which is greater than a predetermined reference activity level, then actions are taken to reduce the rotational velocity of the drive spindle motor to its lowest operational level, or just below the lowest operational level without stopping the disk. The spindle motor is accessed by the microprocessor through a spindle motor control unit. In the case of a constant linear velocity disk drive, the spindle motor is indirectly controlled by the microprocessor sending a message to an actuator to move a data head to a track that is near the outer periphery of the disk medium. In order to maintain a constant linear velocity, the spindle control slows the angular velocity of the motor resulting in a reduction of power consumed. When it is necessary to access data again, thedrive enters an active state and the head is moved by a microprocessor "seek" command. In the case of a constant angular velocity disk drive having selectablespeeds, the microprocessor controls the motor speed directly. The microprocessor, upon determining that the disk has been inactive for a predetermined threshold period, selects a constant speed that is the lowest operation speed available. This results in a power saving mode being implemented for the disk drive. The drive is returned to normal operational speed by a microprocessor "seek" command. For further savings, the motor is stopped or "spun down" when left inactive for a longer period of time.
Patent CA-2152137-C (CA)
Title: Phenyl-substituted alkenylcarboguanidides carrying perfluoroalkyl groups, a process for their preparation, their use as a medicament or diagnostic agent, and also a medicament containing them
Inventor: SCHWARK JAN-ROBERT
IPC: A61P9/00
Filed: 1995-06-19
Granted: 2007-11-13
Abstract: Phenyl-substituted alkenylcarboguanidides carrying perfluoroalkyl groups, of the formula I (see Formula I) in which the substituents have the meanings stated in the description, and their pharmaceutically suitable salts, are described. They are obtained by reacting a compound II (see Formula II) with guanidine, in which R(1) to R(5) and R(A), R(B), R(C) and R(D) have the stated meaning, and L is a leaving group which easily undergoes nucleophilic substitution. Compounds I are excellent cardiovascular therapeutic agents.
Patent CA-2159674-C (CA)
Inventor: GAY DAVID EARL
IPC: B22F1/10
Filed: 1995-10-02
Granted: 1999-08-17
Abstract: Method of distributing and retaining insoluble additive particles uniformly throughout a mass of moldable metal particles.  The additive particles are suspended in a solution of a polymeric binder and spray-coated onto the metal particles. When the solvent evaporates, the additives remain glued to the metal particles by the binder.
Patent CA-2159779-C (CA)
Inventor: HANDELMAN DORON
IPC: G07C9/00
Filed: 1995-10-03
Granted: 2004-05-11
Abstract: A CATV system including a CATV network and apparatus for transmitting over the CATV network information to a multiplicity of subscriber units, each including a CATV decoder and an IC card reader and writer coupled to the CATV decoder, the IC card reader and writer includes two separate IC card receptacles, such that IC cards inserted into the two separate IC card receptacles are separately accessed by the IC card reader and writer.
Patent CA-2161428-C (CA)
Title: Skin cleansing formulations with terpene solvents and corn meal scrubber
Inventor: HERSH LESLIE J
IPC: A61K8/96
Filed: 1994-01-26
Granted: 1998-09-01
Abstract: There is disclosed various terpene based cleansing formulations for skin. The cleaning formulations include the ingredients of water in which there is dispersed a terpene, nonionic surfactants, corn meal scrubber and preservatives including antimicrobial and antioxidant agents. In one aspect of the invention the skin cleansing formulations includes orange terpenes as the solvent. The nonionic surfactants present in formulation  provide stabilization of the terpene/water mixture, do not soften or otherwise attack the corn meal, and provide detergency for suspending the lifted soil.
Patent CA-2165339-C (CA)
Inventor: ANSBJER JAN
IPC: A01F15/07
Filed: 1994-06-06
Granted: 2002-08-20
Abstract: La présene invention se rapporte à un dispositif (1) se situant dans une installation de mise en balles cylindriques pour matériaux, tels que des déchets, des matériaux fibreux et analogues, comprenant une partie presse pouvant être entraînée qui réceptionne et presse des matériaux prévus, ainsi qu'une partie sortie pour l'évacuation de la balle comprimée (5). La partie presse comprend un tapis sans fin (3) qui peut être entraîné et guidé respectivement, et auquel on peut donner une forme de façon à constituer une chambre de compression (6).
Patent CA-2165557-C (CA)
Title: Implantable magnetic hearing aid transducer
Inventor: BALL GEOFFREY R
IPC: H04R25/00
Filed: 1994-06-27
Granted: 2000-09-19
Abstract: A magnetic transducer (100) for improving hearing in a hearing impaired person comprises a magnet assembly (12) and a coil (14) secured inside a housing (10) which is fixed to an ossicle of a middle ear (JJ). The coil (14) is more rigidly secured to the housing (10) than the magnet (12). The magnet assembly (12) and coil (14) are configured such that conducting alternating electrical current through the coil (14) causes magnetic fields of the coil (14) and magnet assembly (12) to cause the magnet assembly (12) and coil (14) to vibrate relative to one another. Because the coil (14) is mole rigidly secured to the housiog (10) than the magnet assembly (12), the vibrations of the coil (14) cause the housing (10) to vibrate. The vibrations are conducted to the oval window of the ear via the ossicles. In alternate embodiments, the transducer (100) is secured to ossicular protheses that are secured within the middle ear (JJ).
Patent CA-2169561-C (CA)
Title: Process for producing n-amino-1-hydroxy-alkyl-idene-1,1-bisphosphonic acids
Inventor: DAUER RICHARD R
IPC: C07F9/6574
Filed: 1994-08-24
Granted: 2007-02-20
Abstract: A process for continuously producing alkylpyrophosphonate, alkylpyrophosphate and multimers thereof and for producing 4-amino-1-hydrozyalkylidene-l,l-bisphosphonic acids or salts thereof.
Patent CA-2169771-C (CA)
Inventor: ABRAHAM GYOERGY
IPC: G02C7/10
Filed: 1993-08-18
Granted: 2000-02-15
Abstract: L'invention concerne un procédé et un dispositif optiques d'amélioration ou de modification de la vision en couleur humaine et consistant à appliquer un filtre en couleur ayant une transmission spectrale  tau ( lambda ) de sorte qu'il compense, dans trois plages de longeurs d'ondes avoisinant les valeurs maximales des courbes de sensibilité spectrale des récepteurs protos, deuteros et tritos (première, deuxième et troisième couleur fondamentale) d'un oeil humain ayant une vision en couleur normale, les différences entre la sensibilité spectrale P*( lambda ), D*( lambda ), T*( lambda ), telle que déterminée, des récepteurs correspondants de l'oeil dont la vision en couleur est à modifier, et la sensibilité spectrale P( lambda ), D( lambda ), T( lambda ) des récepteurs correspondants d'un oeil humain ayant une vision en couleur normale ou désirée. Le dispositif optique peut être réalisé sous forme d'un monocle, d'une lentille de contact ou d'une lentille intraoculaire, ou par n'importe quel autre instrument optique placé entre l'oeil et l'objet à observer.
Patent CA-2173365-C (CA)
Inventor: GEDDES JOHN J
IPC: H01L21/822
Filed: 1994-08-08
Granted: 2007-10-02
Abstract: A varactor diode having a stepped capacitance-voltage profile, formed in heterostructural integrated circuit technology. Several layers in the diode structure have pulse doping to confine conduction in the diode to a sheet of charge that provides the stepped capacitance-voltage profile. The structural design of the diode may be modified to attain desired capacitance-voltage characteristics.
Patent CA-2179237-C (CA)
Title: Diaphragm pump including improved drive mechanism and pump head
Inventor: PARIKH MANOR M
IPC: F04B49/12
Filed: 1996-06-17
Granted: 2007-02-13
Abstract: A mechanical actuated diaphragm pump for pumping fluids. The pump includes a pump housing having a chamber, a flexible diaphragm forming at least a portion of one wall of the chamber, a reciprocally movable member for causing reciprocal movement of a portion of the diaphragm, a rotating shaft connected to the reciprocally movable member such that rotation of the shaft causes reciprocation of the reciprocally movable member and a motor having an output shaft for driving the rotating shaft. The motor can be alternatively and selectively mounted with respect to the pump housing in a first alternative position such that the output shaft of the motor is fixed to the rotating shaft to drive the rotating shaft, and in a second alternative position such that the output shaft is connected to the rotating shaft through a pair of pulleys to drive the rotating shaft.