baber/WOPTO huggingface dataset:
Patent CA-2694396-A1 (CA)
Title: Targeted binding agents directed to kdr and uses thereof - 035
Inventor: BARRY SIMON THOMAS
IPC: C07K14/71
Filed: 2008-07-23
Abstract: The invention relates to targeted binding agents against KDR and uses of such agents. More specifically, the inven-tion relates to fully human monoclonal antibodies directed to KDR. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of KDR and as diagnostics.
Patent CA-2695205-A1 (CA)
Inventor: GABRIELOV ALEXEI GRIGORIEVICH
IPC: B01J27/185
Filed: 2008-08-04
Abstract: A hydrocarbon oil-impregnated composition that comprises a support material having incorporated therein a metal component and impregnated with a hydrocarbon oil. The hydrocarbon oil-impregnated composition is useful in the hydrotreating of hydrocarbon feedstocks, and it is especially useful in applications involving delayed feed introduction whereby the hydrocarbon oil-impregnated composition is first treated with hot hydrogen, and, optionally, a sulfur compound, prior to contacting it with a hydrocarbon feedstock under hydrodesulfurization process conditions.
Patent CA-2696563-A1 (CA)
Title: Peptides for vaccine
Inventor: HAFNER RODERICK PETER
IPC: A61K39/35
Filed: 2008-08-15
Abstract: The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal combinations of peptides for preventing or treating said allergy.
Patent CA-2698152-A1 (CA)
Inventor: PARISSENTI AMADEO MARK
IPC: G01N30/00
Filed: 2008-09-05
Abstract: Cancerous tumours vary significantly in their response to chemotherapy agents. Currently, it is difficult to reliably assess the level of tumour responsiveness to a chemotherapy regimen during or post-administration. Biomarkers of tumour sensitivity to chemotherapy agents have hitherto been unknown. Such a biomarker would expedite identification of nonresponsive patients, who may then switch to other, possibly more effective regimens. The present invention provides a method for determining tumour responsiveness to a chemotherapy agent, wherein RNA is isolated from tumour cells of a patient before, during, and after chemotherapy. The quality of the RNA can be determined by capillary electrophoresis and assignment of an RNA integrity number (RIN). RIN values during and/or after chemotherapy are inversely proportionate to the level of tumour responsiveness. The tumour RIN is an easily accessed biomarker of tumour responsiveness to chemotherapy. The tumour RIN may also be used to assess the efficacy of a chemotherapy regimen.
Patent CA-2698178-A1 (CA)
Inventor: WINKLER WALTER
IPC: B65G1/14
Filed: 2010-03-31
Abstract: The invention relates to an order-picking installation, a method for order picking and an order-picking system, wherein, for the purpose of fully automated repacking of stock-keeping units from an inbound unit having a plurality of identical stock-keeping units into an outbound unit having a plurality of different stock-keeping units, are provided:   - a separating station for separating the stock-keeping units, which are delivered in an inbound unit composed of a plurality of identical items, into stock-keeping units and/or sub-units of several stock-keeping units, - small-parts store, in which is provided a storage location for each type of stock-keeping unit, with an item-storing position and an item-retrieval position, and - a stacking and/or packaging station for assembling different stock-keeping units and/or sub-units in an outbound unit.
Patent CA-2698710-A1 (CA)
Inventor: THOMPSON BRADLEY D
IPC: F03D11/00
Filed: 2010-04-01
Abstract: A wind turbine is formed of a concrete tower which is erected by slip forming. A primary lifting device is erected onto the tower by being lifted together with the slip form and being subsequently transferred onto the tower from the slip form after the tower has been formed. The nacelle, generator, and rotor of the turbine are then lifted onto the tower using the primary lifting device. A secondary lifting device supported on the tower is used to lower the primary lifting device to the ground after the nacelle, generator and rotor are assembled. The height of the tower is therefore not limited by the availability of suitable cranes so that a greater height of tower can be erected to take advantage of winds at greater elevation.
Patent CA-2698953-A1 (CA)
Title: Washing machine with improved wetting and rinsing feature
Inventor: LEE KYU BUM
IPC: D06F21/08
Filed: 2010-04-06
Abstract: A washing machine includes: a cabinet forming an external appearance and having an open upper portion; a reservoir hanging within the cabinet and allowing washing water to be put therein; a washing tub rotatably disposed within the reservoir and accommodating the laundry; and a spray nozzle spraying washing water into the washing tub such that one boundary of sprayed washing machine reaches a side wall of the washing tub and the other boundary of the sprayed washing water reaches the bottom of the washing tub, wherein the spray nozzle includes: a tube part forming a passage along which washing water is introduced; and a spray part connected with the tube part to spray washing water and disposed such that a spray face against which washing water discharged from the tube part splashes is bent at a certain angle with respect to a discharge direction of the tube part. The laundry can be effectively wet by increasing a spray range of washing water.
Patent CA-2699241-A1 (CA)
Inventor: BEVEC DORIAN
IPC: A61K38/22
Filed: 2008-09-09
Abstract: The present invention is directed to the use of the peptide compound Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn--Val-Ala-Cys-Thr-Gly-Cys-Leu-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fi-brotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Asn-Asp-Asp-Cys--Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
Patent CA-2699940-A1 (CA)
Inventor: WHITE PHILIP
IPC: B62K21/12
Filed: 2010-04-14
Abstract: A bicycle comprising a frame, a front fork pivotably mounted to the frame, and handle bars coupled to the fork for pivoting with the fork, the handle bars including a pair of laterally spaced arm rests and a pair of laterally spaced extension hand grips, the extension hand grips provided forwardly of the arm rests such that a rider resting his forearms of his arms on the arm rests with his arms extending forwardly from the arm rests may grasp the extension hand grips with his hands, characterized by an aerodynamic element is provided mounted to the handle bars between the arm rests.
Patent CA-2703001-A1 (CA)
Inventor: KLAUSEN MARIUS
IPC: A61K8/02
Filed: 2007-11-09
Abstract: A patch device (1; 16) comprising a backing layer (2) which is a barrier to at least a fragrance (14), a reservoir layer (4), which is attached to the backing layer (2) and serves for holding a volume of one or more fragrances (14), and a cover layer (59 for covering the reservoir layer (4) when filled with fragrance (14) is disclosed. The cover layer (5) is permeable to vapour from at least one fragrance (14), which cover layer (5) in a first position of the patch device (1;16), in which the reservoir layer (4) is free of fragrance (14), is situated at least partly offset or dislocated from the reservoir layer (4), and which cover layer (5) in a second position of use, in which the volume of one or more fragrances (14) has been delivered to the reservoir layer (4), covers the reservoir layer (4). Support sheets (17, 18), which supports the backing layer (2) and a flap part (10) of the cover layer (5), serves as a tool for applying the flap part (10) into covering relationship to cover and/or encapsulate the reservoir layer 4.
Patent CA-2703120-A1 (CA)
Inventor: REID MARION
IPC: C12Q1/68
Filed: 2008-10-20
Abstract: Disclosed herein are nucleic acid molecules which permit the accurate and direct determination of blood groups based on the presence of certain genes. A method of determining blood groups is also provided.
Patent CA-2705155-A1 (CA)
Inventor: GILDENHUYS JOHANNES JOCHEMUS
IPC: C07C2/36
Filed: 2008-10-29
Abstract: A process (10) for polymerising or oligomerising a hydrocarbon includes feeding a liquid hydrocarbon reactant (32) and a liquid evaporative cooling medium into a bulk liquid phase (14) which includes polymeric or oligomeric product admixed with a catalyst, and allowing at least a portion of the liquid hydrocarbon reactant and the liquid evaporative cooling medium to vapouhse to form bubbles rising through the bulk liquid phase (14), with the hydrocarbon reactant polymerising or oligomerising to form the polymeric or oligomeric product and with the evaporation of both the liquid hydrocarbon reactant and the liquid evaporative cooling medium effecting heat removal from the bulk liquid phase (14). Gaseous components are withdrawn (26) from a head space, cooled (28) and separated (30). Condensed hydrocarbon reactant and condensed cooling medium are recycled (32) to the bulk liquid phase (14).
Patent CA-2705233-A1 (CA)
Inventor: RAKSI FERENC
IPC: A61F9/01
Filed: 2008-11-07
Abstract: Systems (10) and methods (100) of incising a portion of a material include creating a sub-surface separation in a region of the material, and incising a periphery of the region with a pulsed laser beam to produce an edge of the portion. The edge includes a periodically varying shape to secure the portion to the material when the portion is reintegrated. The system (10) includes a laser (14) producing the pulsed laser beam, a scanner (20) operable in response to a control signal, and a controller (22) coupled to the scanner. The controller produces the control signal. In response to the control signal, the scanner creates a sub-surface separation in the region with the pulsed laser beam and incises the periphery of the region with the pulsed laser beam to produce the edge (72, 78, 84) with the periodically varying shape.
Patent CA-2709950-A1 (CA)
Inventor: LIANG ALFRED
IPC: A61K9/24
Filed: 2008-12-16
Abstract: Provided herein are pharmaceutical compositions comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions are also demonstrated.
Patent CA-2711261-A1 (CA)
Inventor: VILA ERRANDONEA JULIA
IPC: G07C9/00
Filed: 2008-10-01
Abstract: The invention relates to a programmable electronic access control system including: an updating unit (1) which operates in conjunction with a central control unit (2) and is provided with management software for global control of installation access, access elements (3) associated with the entrance/exit routes, and a credential (4) associated with each system user. In addition, each updating unit (1) includes means for the bi-directional transfer of data in relation to user credentials (4) and the central control unit (2). The updating unit (1) transfers only the information concerning a particular user and the installation closure plan to the user credentials (4), while receiving information stored on the user credential (4) relating to past events associated therewith, which have been transferred to each of the access elements (3).
Patent CA-2712414-A1 (CA)
Inventor: WIDMANN RUDOLF STEFAN
IPC: A61K31/5377
Filed: 2008-12-22
Abstract: The present invention relates to a pharmaceutical composition in the form of a storage-stable solution for the parenteral administration of ultrashort-effective .beta.-adrenorecep-tor antagonists, comprising a) an ultrashort-effective .beta.-adrenoreceptor antagonist and/or a pharmaceutically acceptable salt thereof, b) water, and c) a cyclodextrin and/or a functional cyclodextrin derivative. The composition according to the invention has high stability, even without the presence of additional adiuvants.
Patent CA-2712835-A1 (CA)
Inventor: RITTER THOMAS
IPC: A62B35/00
Filed: 2010-08-13
Abstract: The invention is illumination gear that has a strap pad slidably mounted on a strap. A battery-operated lamp is mounted on the strap pad. The strap pad with lamp may be adjusted anywhere along the strap, so as to adjust the position of the lamp to a desired height. The illumination gear may be constructed as a harness, as a vest, or as a set of suspenders. Anchor straps may be provided on the vest or the harness, to secure the straps to belt loops on a trouser waistband or to another garment, to prevent the illumination gear from riding up or shifting position.
Patent CA-2713004-A1 (CA)
Inventor: GILBERT JAMES A
IPC: G01R35/00
Filed: 2010-08-11
Abstract: An impedance monitoring circuit for an electrosurgical generator is disclosed. The monitoring circuit includes an isolation transformer coupled to at least one of an active terminal and a return terminal of an electrosurgical generator, wherein the isolation transformer includes a primary winding coupled to a reference resistor and a secondary winding coupled to a load. The monitoring circuit also includes a driver configured to transmit a sensor signal to the reference resistor and the load, a primary converter coupled to the reference resistor and the load and configured to detect a primary converted signal as a function of the sensor signal passing through the reference resistor and the load. The monitoring circuit further includes a secondary converter coupled to the driver and configured to detect a secondary converted signal as a function of the sensor signal prior to passing through the reference resistor and the load and a controller configured to determine a fault condition based on the primary and secondary converted signals.
Patent CA-2714395-A1 (CA)
Inventor: XIA ERNING
IPC: A61K47/08
Filed: 2009-02-19
Abstract: A pharmaceutical formulation that is effective in adversely affecting the viability of microorganisms or in inhibiting their growth and that provides better safety and/or comfort to the users comprises at least a polyanionic material and at least a source of hydrogen peroxide. The formulation can comprise an ophthalmically active agent for treating or controlling a disease or disorder of the eye.
Patent CA-2714660-A1 (CA)
Inventor: LASTOW OREST
IPC: A61M15/00
Filed: 2009-02-11
Abstract: The invention relates to an inhaler which comprises a base having a plurality of consecutive sealed cavities containing medicament. Foil portions are on one side attached to the base for sealing the medicament within respective associated cavities. A plurality of separating elements are attached to the other side of the foil portions, each separating element being associated with a respective cavity for separating a foil portion from that cavity. Each separating element can be moved-away from its associated cavity so that the sealing foil portion is separated from the cavity which is thereby uncovered so that medicament contained therein is enabled to become entrained in a fluid flow, and then returned with the attached foil portion to cover its associated cavity. The invention also relates to a method in an inhaler.
Patent CA-2716304-A1 (CA)
Inventor: BENNETT ALAN E
IPC: F24F11/02
Filed: 2010-10-04
Abstract: An HVAC system includes an enclosure for containing components of the HVAC system. Associated with the enclosure is an HVAC system control unit including a microcontroller for controlling an operation of the HVAC system. The HVAC system control unit further includes a memory associated with the microcontroller and configured to store data associated with operation of the HVAC system. The microcontroller is configurable to directly transfer the data between the memory and a portable flash memory device. The HVAC system control unit further includes a portable flash memory device interface for coupling the portable flash memory device directly thereto.
Patent CA-2716359-A1 (CA)
Inventor: MEASOM RONALD J
IPC: D07B1/14
Filed: 2008-02-28
Abstract: An uncured, composite rope includes at least one inner tow of structural fibers of a first material and a plurality of outer tows of structural fibers disposed about the at least one inner tow, the structural fibers of at least one of the plurality of outer tows being made from a second material that is different from the first material.  The uncured, composite rope further includes an uncured polymeric resin impregnated into the at least one inner tow and the plurality of outer tows.
Patent CA-2717854-A1 (CA)
Title: Allogeneic cancer cell-based immunotherapy
Inventor: PODACK ECKHARD R
IPC: A61K39/00
Filed: 2009-03-03
Abstract: Cell-based immunotherapy (e.g., immunization or vaccination) may be improved by frequent administration to a human subject of allogeneic cancer cells secreting a modified heat shock protein (e.g., gp96), depletion of B cells in the subject, or both. Antigen (e.g., epitope derived from neoantigen or tumor antigen of allogeneic or syngeneic cancer cells) may induce a specific immune response in the subject. For example, the epitope bound in an immunogenic complex with the secreted heat shock protein may be obtained from allogeneic cancer cells coexpressing both secreted gp96 and antigen, or from syngeneic cancer cells of the subject expressing only antigen.
Patent CA-2719092-A1 (CA)
Inventor: CHRISTIANSEN SVEND ERIK
IPC: H05B6/06
Filed: 2009-03-03
Abstract: The invention relates to a method for dynamic wave form correc tion of a power supply of an induction heating de-vice (3), a) where an input power signal (Uin), especially an input volt age signal, comprising waves with an input power frequen-cy (fin) is provided by an AC power source (1), b) where a frequency converter (2) rectifies the input power signal (Uin) into a half waves signal (Uh), especially a half wave voltage signal, b1) where a half wave of the half waves signal is delimited by two subsequent zero-crossings (t.theta., t1;t1, t2; t2, t3), b2 ) where the time lag between the two zero-crossings defines a half wave duration (th), c) where the frequency converter (2) further converts the half waves signal (Uh) into to a working signal (Iw), especially a working current signal, for supplying the induction heating device (3), d) where in a frequency shifting operation (5) a working frequency (fw) of the working signal (Iw) is first increased from a first working base frequency (f1) to a maximum frequency (fmax) and then decreased to a second base frequency (f2) within a time, which is smaller than the half wave duration (th), e) where the first working base frequency (f1) is not equal to the second working base frequency (f2) and/or a zero crossing (t0, t1, t2, t3) of the half wave signal (Uh) is passed within the frequency shifting operation. Furthermore, the invention relates a an arrange-ment for dynamic wave form correction of a power supply of an induction heating device (3), particularly according to one of the preceding claims, a) with an AC power source (1) for providing an input power signal (Uin), especially an input voltage signal, comprising waves with an input power frequency (fin), b) with a frequency converter (2) for rectifying the input power signal (Uin) into a half waves signal (Uh), especially a half wave voltage signal, b1) where the frequency converter (2) preferably com-prises at least one full bridge and/or at least one half bridge and/or a single switch, b2) where a half wave of the half waves signal is delimited by two subsequent zero-crossings (t.theta., t1;t1, t2; t2, t3), b3) where the time lag between the two zero-crossings defines a half wave duration (th), c) where by the frequency converter (2) further the half waves signal (Uh) is convertable into to a working signal (Iw), especially a working cur-rent signal, for supplying the induction heating device (3), d) where in a frequency shifting operation (5) a working frequency (fw) of the working signal (Iw) is first increasable from a first working base frequency (f1) to a maximum frequency (fmax) and then decreasable to a second working.base frequency (f2) within a time, which is smaller than the half wave duration (th), e) where the first working base frequency (f1) is not equal to the second working base frequency (f2) and/or a zero crossing (t0, t1, t2, t3) of the half wave signal (Uh) is passed or passable within the frequency shifting operation.
Patent CA-2719265-A1 (CA)
Inventor: FORNAGE MARTIN
IPC: G01R19/165
Filed: 2009-03-17
Abstract: A method and apparatus for providing AC voltage measurements. The apparatus comprises an AC voltage monitor for determining at least a first and a second voltage representing an AC  voltage of an AC circuit, generating a serial data stream frame comprising data representing the at least a first and a second voltage, and transmitting the serial data stream frame.
Patent CA-2719556-A1 (CA)
Inventor: WILKES IAN PAUL
IPC: C04B22/00
Filed: 2009-03-23
Abstract: A process for reducing the set time a plaster slurry. The process comprises the steps of, providing a pre-determined amount of water, providing a pre-determined amount of the plaster, mixing the water and the plaster together at a first time to form a slurry, and, re-directing a portion of the slurry formed at the first time to combine with slurry formed at a second time.
Patent CA-2723043-A1 (CA)
Inventor: GOSSELIN ROBERT MICHAEL
IPC: B60L50/16
Filed: 2003-03-14
Abstract: A method and apparatus for producing a record for use in controlling a supply of power from an electric generator powered by a prime mover in a hybrid electric vehicle. A set of operating characteristics of the vehicle known to occur when the vehicle is operated under certain operating conditions is associated with respective power values approximately equal to the actual power produced by the generator when the generator is operated under operating conditions approximately equal to such certain operating conditions, to facilitate lookup of an optimal set of operating conditions that optimizes operating characteristics of the vehicle in response to a power value.
Patent CA-2727401-A1 (CA)
Inventor: BOYKIN CHRISTOPHER M
IPC: B27B19/00
Filed: 2009-05-28
Abstract: A blade coupling mechanism (116) for a hand-held surgical cutting instrument (102) includes a first coupling member (118) including a first blade-contacting surface (130) and a first outer perimeter sidewall (132) ad-jacent the first blade contacting surface. It also includes a second coupling member (120) including a second blade--contacting surface (160) facing the first blade-contacting surface of the first coupling member. The second coupling member includes- a second outer perimeter sidewall (164) adjacent the second blade contacting surface. The second blade-contacting surface and the second outer perimeter sidewall meet to define an outer edge (168). The second coupling member including a bore (156) through the sec-ond blade contacting surface. The bore and the second blade contacting surface meeting to define an inner edge (166). Blade- engaging protrusions project (172) from at least one of the first and second blade-contacting surfaces.  The protrusions are spaced closer to the outer edge than the inner edge.