baber/WOPTO huggingface dataset:
Patent CA-2993042-A1 (CA)
Inventor: CIRILLO AGOSTINO
IPC: C07K14/075
Filed: 2005-01-18
Abstract: The present invention provides recombinant replication-defective adenoviral vectors derived from chimpanzee adenoviruses and methods for generating recombinant adenoviruses in human E1-expressing cell lines. The invention also provides compositions and methods suitable for use for the delivery and expression of transgenes encoding immunogens against which a boosted immune response is desired. The invention further provides methods of generating clinical grade vector stocks suitable for use in humans. In a particular embodiment the invention contemplates the use of vectors comprising transgenes which encode tumor associated antigens in vaccines and pharmaceutical compositions for the prevention and treatment of cancer.
Patent CA-2993590-A1 (CA)
Inventor: ATTO ZAID
IPC: A61M39/02
Filed: 2018-01-31
Abstract: A radially expandable trocar or cannula system for use in minimally invasive surgeries. The cannula creates a port access with an initial small internal diameter. Upon engagement of a ring, the cannula of the devices, which is made of a number of elongate rigid members, expand radially via mechanical mechanism between the elongate rigidmembers and the ring, towards larger radial location, thereby creating a larger internal diameter for the port. The elongate rigidmembers can be prevented from unintended movement when the system is at the un-expanded state, during expansion and when it is expanded to the desired larger diameter. Example embodiments include methods of preventing gas loss from the tissue that would occur through the gaps created during expansion.
Patent CA-2993890-A1 (CA)
Title: Downhole completion system sealing against the cap layer
Inventor: HAZEL PAUL
IPC: E21B23/06
Filed: 2016-08-17
Abstract: The present invention relates to use of an annular barrier in a cementless downhole completion system, wherein the annular barrier comprises a tubular metal part being mounted as part of a first well tubular metal structure arranged in a borehole in a formation and the annular barrier is arranged opposite an impermeable cap layer in the formation. Furthermore, the invention relates to a downhole completion system for completing a well having a top, comprising a formation comprising a cap layer having an upper end and a lower end, a borehole extending through the cap layer to provide an inner cap layer face and, a first well tubular metal structure arranged in the borehole comprising a first annular barrier and a second annular barrier. Each annular barrier comprises a tubular metal part, the tubular metal part being mounted as part of the first well tubular metal structure, an expandable tubular surrounding the tubular metal part, each end section of the expandable tubular being connected with the tubular metal part, an annular barrier space between the tubular metal part and the expandable tubular, and an expansion opening in the tubular metal part through which pressurised fluid passes for expanding the expandable tubular and bringing the annular barrier from an unexpanded position to an expanded position, wherein the first annular barrier is arranged at the upper end of the first well tubular metal structure, and in the expanded position, the expandable tubular of the first annular barrier overlaps the cap layer, and the second annular barrier is arranged at the lower end of the first well tubular metal structure, and in the expanded position, the expandable tubular of the second annular barrier overlaps the cap layer. Furthermore, the present invention relates to a completion method for a downhole completion system.
Patent CA-2996420-A1 (CA)
Title: Procedes et compositions pour vecteurs viraux evitant les anticorps
Inventor: ASOKAN ARAVIND
IPC: C12N15/864
Filed: 2016-09-28
Abstract: La présente invention concerne des protéines de capsides de virus adéno-associés comprenant une modification de la séquence d'acides aminés et des vecteurs viraux comprenant la protéine de capside de virus adéno-associé modifiée. L'invention concerne également des procédés d'administration des vecteurs viraux et des capsides virales de l'invention à une cellule ou à un sujet in vivo.
Patent CA-2998049-A1 (CA)
Inventor: MCCAIG RHYS
IPC: H04L12/26
Filed: 2018-03-13
Abstract: Systems, apparatuses, and methods are described for monitoring device data and/or gateway data. Devices may be connected to a network via a gateway device. Data transmitted and/or received by one or more of the devices may be captured and monitored to determine various parameters associated with the one or more devices. Data associated with the gateway device may also be captured and monitored. Signal strengths, device statuses, network security, and/or other metrics may be determined based on monitored data.
Patent CA-2999826-A1 (CA)
Inventor: SYCHEV MAXIM BORISOVITCH
IPC: H04N19/82
Filed: 2015-09-25
Abstract: The present invention relates to a video coder for predictive coding a video stream of subsequent frames according to motion compensation into an encoded video bit stream, comprising a frame buffer configured to store at least one reference frame of the video stream, a prediction unit configured to generate a prediction block of a current block of a current frame from a reference block of the reference frame according to a motion vector having fractional-pel resolution, said fractional-pel resolution defining an integer-pel position and fractional-pel positions. The prediction unit is configured to interpolate the reference block according to the fractional-pel resolution via one of the at least three following interpolation filters: a blurring interpolation filter, a tap filter, and the tap filter followed by a sharpening filter.
Patent CA-3009553-A1 (CA)
Title: Agents that inhibit the binding of cfh to cd11b/cd18 and uses thereof
Inventor: SENNLAUB FLORIAN
IPC: C07K16/28
Filed: 2016-12-23
Abstract: The present invention relates to agents inhibiting the interaction between CFH and CD11b/18. The present invention also relates to the use of said agents, in particular for treating inflammatory disorders, such as age-related macular degeneration.
Patent CA-3009904-A1 (CA)
Inventor: QU XIANGDONG
IPC: C07K16/40
Filed: 2016-12-20
Abstract: The present invention provides a PCSK9 antibody, an antigen-binding fragment thereof, and a medicinal application thereof. Provided in the invention is a chimeric antibody and a humanized antibody, both comprising a CDR of the PCSK9 antibody, and a pharmaceutical composition comprising the PCSK9 antibody and an antigen-binding fragment thereof, and an application of the PCSK9 antibody as a lipid-lowering agent. The invention specifically relates to an application of a humanized PCSK9 antibody for preparing a pharmaceutical drug to treat a PCSK9-induced disease or symptom.
Patent CA-3014160-A1 (CA)
Title: Dispositif de transporteur
Inventor: FUJIO YOSHIHIKO
IPC: B65G17/32
Filed: 2017-02-13
Abstract: L'invention concerne un dispositif de transporteur qui tout en supportant des articles à l'aide d'une pluralité de corps de support d'article alignée, en assure le transport, et qui possède des éléments de comblement de vide (16) disposés entre deux corps de support d'article. Des plaques de remplissage (16) servant d'éléments de comblement de vide sont poussées vers des plateaux (14) par un ressort (36), et ainsi les plaques de remplissage (16) sont maintenues dans un état de contact avec les plateaux (14).
Patent CA-3016089-A1 (CA)
Inventor: GAITHER HUGH
IPC: A61F13/08
Filed: 2018-01-22
Abstract: A knit sock is integrally formed of a body yarn in circumferential courses and axial wales, and includes a foot portion having a heel and a toe, and an ankle portion joined to the foot portion and defining an open leg end of the sock. A first targeted compression zone is formed with the foot portion between the heel and the toe, and includes spaced- apart axial compression ridges extending axially outward from the heel at a first end of the first compression zone to a second end of the first compression zone. A second targeted compression zone is formed with the ankle portion between the heel and the open leg end of the sock, and includes spaced-apart axial compression ridges extending axially outward from the heel at a first end of the second compression zone to a second end of the second compression zone.
Patent CA-3016563-A1 (CA)
Inventor: LOEW ANDREAS
IPC: C07K14/55
Filed: 2017-03-21
Abstract: Cette invention concerne des molécules multispécifiques qui comprennent i) un fragment de ciblage de tumeur ; et un, deux ou la totalité des fragments suivants : (ii) un recruteur de cellules immunitaires (p. ex., choisi parmi un recruteur de cellules NK, un recruteur de cellules T, un recruteur de cellules B, un recruteur de cellules dendritiques, ou un recruteur de cellules macrophages) ; (iii) une molécule de cytokine; et/ou (iv) un fragment de modification stromale. Des acides nucléiques codant pour celles-ci, des procédés de production des molécules précitées, et des méthodes de traitement du cancer les utilisant sont en outre décrits.
Patent CA-3018220-A1 (CA)
Inventor: MUHLENFELD STEPHANIE
IPC: A41C3/00
Filed: 2017-03-28
Abstract: A harness system for adjusting support of a garment (200) is provided herein. The garment (200) with a harness system includes a body (202) and a liner (222) having harness straps. The harness straps slide through openings in shoulder straps of the body (202). The harness straps are then laced through a series of maintainers in the back of the body (202). The harness straps having terminally-located tabs that may be pulled from the back of the body (202) toward the front of the body (202) and affixed thereto. The placement of the tabs, when pulled toward the front of the body (202) and attached thereto, determines the fit and support of the garment (200). By manipulating the tabs of the harness system, a wearer may adjust the length of the harness straps, back and posture support, and the lift provided by the liner (222). The harness system creates a customizable fit and support level.
Patent CA-3018791-A1 (CA)
Title: Systemes et procedes permettant une navigation de drone autonome
Inventor: PARKER JON LELAND
IPC: G01C21/20
Filed: 2017-03-21
Abstract: La présente invention concerne des systèmes, des procédés et un support lisible par ordinateur pour un système de navigation de drone. Des modes de réalisation donnés à titre d'exemple concernent un drone doté d'un dispositif d'imagerie et d'un dispositif informatique en communication avec le drone. Le dispositif informatique reçoit une sélection d'un plan de CAO qui comprend des mesures d'une partie intérieure d'un bâtiment et reçoit un point de départ et un point d'arrivée sur le plan. Le dispositif informatique analyse le plan et génère un itinéraire du point de départ au point d'arrivée et détermine un premier ensemble d'instructions en termes de distance et de degrés pour suivre l'itinéraire généré. Le dispositif informatique traite le premier ensemble d'instructions pour générer un second ensemble d'instructions en termes de lacet, de tangage et de roulis. Le second ensemble d'instructions est exporté au drone pour contraindre le drone à suivre l'itinéraire généré dans le bâtiment.
Patent CA-3021591-A1 (CA)
Inventor: ERICKSON MATTHEW
IPC: A61D7/00
Filed: 2017-05-15
Abstract: Il est décrit un appareil d'injection destiné à la volaille à éléments de capture rotatifs et des procédés d'utilisation de celui-ci. Chaque appareil d'injection peut comprendre au moins un élément de capture rotatif et une unité d'injection conçue pour changer la position d'une aiguille d'injection entre une position d'injection et une position rétractée par rapport à tout élément de capture susmentionné dans la présente. La rotation d'au moins un élément de capture peut entraîner le pliage ou le regroupement d'une manière répétitive à un emplacement d'injection pour améliorer l'administration sous-cutanée des substances à l'aide d'une aiguille d'injection avancée dans la peau pliée ou regroupée le long d'un axe d'injection aligné avec tout axe de rotation de tout élément de capture rotatif.
Patent CA-3022572-A1 (CA)
Inventor: MITCHELL AOY TOMITA
IPC: C12Q1/68
Filed: 2017-04-29
Abstract: La présente invention concerne des méthodes et des compositions pour évaluer une quantité d'acides nucléiques non-natifs dans un échantillon, tel que ceux provenant d'un sujet. Les méthodes et les compositions de la présente invention peuvent être utilisées pour déterminer un risque d'affection chez un sujet.
Patent CA-3028427-A1 (CA)
Title: Bong stem filter
Inventor: CYR CHRISTIAN L
IPC: A24D3/10
Filed: 2018-12-21
Abstract: The Bong Stem Filter is a filtration insert intended for the reduction of Cannabis residue, Tobacco residue and other substance residues in a Bong smoking apparatus. Too often do Bong users complain of a need to clean their accessories which includes the Bong Down Stem. The consistent issue of a clogged Bong Down Stem is a common factor amongst these Bong users. Raising concern however is when they do in fact clean these accessories and bongs the residue from them tends to be a clumped rather sticky substance. It has the ability to build up in water filtration stations and household plumbing leading to an array of chemicals to be added to the water sources already contaminated once by the residue. This is where the Bong Stem Filter has a role comprised of a Bong Stem Sleeve Filter to act as a porous device removing the impurities or solid particles from a liquid or gas passing through it. Also comprised of a Bong Stem Filter Sleeve which acts as a holder for said Bong Stem Sleeve Filter and as a container for the residue which builds up during use. The Bong Stem Filter Sleeve has a light Sugar based Glue coating to ensure an adhesive effect upon contact with particles which otherwise manage to pass through the Bong Stem Sleeve Filter. The Bong Stem Filter Sleeve and the Bong Stem Sleeve Filter both require the same shape for proper insertion of said Bong Stem Filter into the Bong Down Stem. The Bong Stem Filter allows for the disposal of the residue left in itself and not in the Bong Down Stem or Bong after use by biodegradation.
Patent CA-3033381-A1 (CA)
Title: Method for generating mesoderm and/or endothelial colony forming cell-like cells having in vivo blood vessel forming capacity
Inventor: YODER MERVIN C
IPC: C12N5/074
Filed: 2017-08-04
Abstract: The present disclosure relates generally to methods and compositions useful in cell and tissue biology and therapeutics. In particular, an in vitro method for differentiating pluripotent stem cells into KDR+NCAM+APLNR+ mesoderm cells and/or SSEA5-KDR+NCAM+APLNR+ mesoderm cells is provided. The disclosed mesoderm cells may be used to generate blood vessels in vivo and/or further differentiated in vitro into endothelial colony forming cell-like cells (ECFC-like cells). Purified human cell populations of KDR+NCAM+APLNR+ mesoderm cells and ECFC-like cells are provided. Test agent screening and therapeutic methods for using the cell populations of the present disclosure are provided.
Patent CA-3037062-A1 (CA)
Title: Structural panel assembly for mounting building walls and method for mounting building walls using same
Inventor: TREMBLAY MARCO
IPC: E04F13/21
Filed: 2017-09-15
Abstract: A structural panel having a structural inner core with a male member and a female member. The female member is configured to receive the male member of a vertically adjacent panel therein and has a locking slot. The structural panel also includes a locking member operatively engageable to the male member and configurable between an unlocked configuration where it does not substantially project outside of lateral wall surfaces of the male member and a locked configuration where it projects outside of at least one of the lateral wall surfaces of the male member and is engaged in the locking slot of the vertically adjacent panel. A panel assembly, a method for building a building wall using multiple structural panels, a corner securement assembly for at least two horizontally adjacent structural panels and a method for securing two horizontally adjacent panels in a corner configuration are also provided.
Patent CA-3041754-A1 (CA)
Title: Systemes et procedes de commande d'une station de travail interactive bases sur une entree biometrique
Inventor: DESROCHES LEON
IPC: A47B13/00
Filed: 2016-11-10
Abstract: La présente invention concerne des systèmes et des procédés permettant de déplacer un plateau supérieur de table d'une station de travail basés sur une entrée biométrique associée à un utilisateur, le procédé étant exécuté par un contrôleur qui est configuré pour envoyer des signaux de commande à des actionneurs pour déplacer le plateau supérieur de la table. Un procédé consiste à : accéder au profil d'un utilisateur associé à un dispositif d'utilisateur ; déterminer des paramètres de déplacement du plateau supérieur de la table, basés sur le profil de l'utilisateur, pour obtenir les entrées biométriques souhaitées de l'utilisateur de la station de travail à une ou plusieurs reprises pendant le déplacement du plateau supérieur de la table ; et répéter une ou plusieurs itérations consistant à : déplacer le plateau supérieur de la table sur la base des paramètres, en envoyant des signaux de commande aux actionneurs du plateau supérieur de la table ; recevoir, dans un dispositif de mémoire de données, des entrées biométriques réelles de l'utilisateur de la station de travail ; comparer les entrées biométriques réelles reçues avec les entrées biométriques souhaitées ; et si les paramètres ne permettent pas d'obtenir les entrées biométriques souhaitées, ajuster les paramètres.
Patent CA-3042351-A1 (CA)
Title: System and method for monitoring phototoxicity during ophthalmic surgery
Inventor: BACHER GERALD DAVID
IPC: A61B3/13
Filed: 2017-11-22
Abstract: The present disclosure provides a system and method for monitoring phototoxicity caused by vitreous visualization device ("VVD") illumination during ophthalmic surgery. The systems and methods determine the cumulative amount of optical energy incident on the retina, which corresponds to phototoxicity, the distance between a cutter of the VVD and the retina, and areas where the vitreous has been removed, or any combination thereof. The disclosure further provides a method for monitoring and preventing phototoxicity caused by VVD illumination during ophthalmic surgery. The method may further include determining the distance between a cutter of the VVD and the retina, and determining areas where the vitreous has been removed based on focus areas of the retina that the plurality of light spots has contacted.
Patent CA-3044244-A1 (CA)
Inventor: FITZGERALD DENNIS
IPC: C07K16/24
Filed: 2017-11-15
Abstract: L'invention concerne un procédé de traitement du psoriasis chez un patient préalablement traité par administration d'un anticorps contre IL-12/23p40 et ayant été identifié comme n'y répondant pas de manière adéquate, par administration d'un anticorps spécifique d'IL -23, par exemple, le guselkumab, en une quantité sûre et efficace et le patient atteint un score PASI75, PASI90, PASI100 ou IGA 0 ou 1, mesuré 16, 24, 32, 40 et 48 semaines après traitement initial.
Patent CA-3046111-A1 (CA)
Inventor: LINDEMANN HARRY
IPC: B65G23/08
Filed: 2017-12-15
Abstract: Motor-driven conveying roller (1) for conveying installations for the purpose of conveying containers, pallets and the like, having a roller body (2), of which the outer circumferential surface constitutes a bearing surface for articles, having a drive unit (18), which is arranged within an interior (14) of the roller body (2), and having a coupling unit (30), which is designed for transmitting a torque from the drive unit (18) to an inner circumferential surface (12) of the interior (14) of the roller body (2) and has a coupling bushing (50), which has a drive portion, which is connected to the drive unit (18), and an outer, peripheral output portion (52), wherein the coupling bushing (50) is connected to the inner circumferential surface (12) of the roller body (2) in a frictionally fitting and/or integral manner, for torque-transmitting purposes, only at certain points.
Patent CA-3047138-A1 (CA)
Inventor: KHAN SHAHARYAR
IPC: A61P9/00
Filed: 2018-01-05
Abstract: La présente invention concerne un nouveau dérivé de phényle, le 5-[(2,4-dinitrophénoxy)méthyl]-l-méthyl-2-nitro-lH-imidazole ou un sel pharmaceutiquement acceptable de celui-ci, qui est utile pour réguler l'activité des mitochondries, réduire l'adiposité, traiter des maladies comprenant le diabète et des complications associées au diabète.
Patent CA-3047737-A1 (CA)
Inventor: GAO JING DUO J G D
IPC: B32B7/14
Filed: 2019-06-25
Abstract: FrözenRoof is an innovative car shelter which can be installed much faster than any traditional car shelters. Unlike traditional car shelters, FrözenRoof does not utilize a series of thick metal beams in order to provide the structural integrity needed to support the snow, ice and rain of the winter months, instead it utilizes water's properties in order to do so: the pattern created within its tarp allows FrözenRoof to provide the structural integrity needed to support the weight of the winter precipitation.  FrözenRoof consists of a series of highly bendable poles which can be easily broken down into small segments, and a double-layered tarp containing many cells for water to flow into created through the use of a series of inwardly-curved rhombus shaped sticking elements. Setting it up is very easy as it consists of only combining the poles together, installing the tarp over the poles, filling the tarp with water and letting the water within the tarp freeze.
Patent CA-3047993-A1 (CA)
Inventor: HILFIGER MATTHEW GARY
IPC: C09K8/035
Filed: 2018-01-11
Abstract: The present disclosure relates to the creation of emulsifiers for use in an oil-based drilling mud. The disclosed emulsifiers may be created by the reaction of synthetic linear saturated fatty acids and polyamines under the conditions specified. The synthesized product may be used as a replacement for the wetting agent in conventional muds. Further improvements in conventional drilling muds are also disclosed where the synthesized product is used to replace incumbent wetting agents and the primary emulsifiers are replaced by synthetic fatty acids.
Patent CA-3049577-A1 (CA)
Inventor: GLAUDE MATHIEU
IPC: G06F17/00
Filed: 2019-07-12
Abstract: Methods, systems, and techniques for processing firearm-related data. Stored on a blockchain are a hash of a firearm license and personal data identifying the licensee, which can be used to retrieve the hash from the blockchain. When the licensee wishes to acquire a firearm, the licensee produces a copy of the license that, to the vendor, is unverified. The vendor retrieves the hash from the blockchain and independently determines a hash of the unverified license. When the two hashes match, the vendor trusts that the previously unverified license is authentic. A non-blockchain database is also used to store a copy of the license, providing redundancy and data integrity/security.
Patent CA-3050228-A1 (CA)
Inventor: ZILBERMAN ISRAEL
IPC: A61B18/00
Filed: 2019-07-19
Abstract: Described embodiments include a system that includes a radiofrequency-current (RF-current) generator and a processor.                                                      The processor is configured to cause the RF-current generator to generate a plurality of pulses of RF  current for application to tissue of a subject, each of the pulses having a power whose maximum value is greater than 80 W and a duration that is less than 10 s, and an intermission between successive ones of the pulses being less than 10 s.  The processor is further configured to, while each one of the pulses is applied to the tissue, receive at least one signal that indicates a measured temperature of the tissue, and, in response to the measured temperature, control the power of the pulse. Other embodiments are also described.