baber/WOPTO huggingface dataset:
Patent JP-2009131512-A (JP)
Title: Dishwasher
Inventor: KODAMA KOJI
IPC: A47L15/46
Filed: 2007-11-30
Abstract: <P>PROBLEM TO BE SOLVED: To provide a dishwasher capable of suppressing a rinse agent from being wasted.  <P>SOLUTION: In the DISHWASHER 1, when a rinse agent supply signal is outputted by a microcomputer 32 to a rinse agent supply pump 39, the rinse agent is supplied into a rinsing waterway linked to a hot water storage tank 18 by the rinse agent supply pump 39. Thus, when the rinse agent supply signal is outputted while a rinse pump 28 is operating, the rinse agent is mixed with the hot water in the rinsing waterway when hot water inside the hot water storage tank 18 jets to a cleansing chamber 3 by a rinsing pump 28, and the hot water containing the rinse agent is jetted to a plate P. Timing at which the rinse agent supply signal is outputted occurs after a prescribed time has passed since a rinse step starts. Thus, in the rinse step, the rinse agent is not charged the prescribed time before its start, so that the rinse agent can be suppressed from being wasted.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009138803-A (JP)
Title: Spherical bearing and spherical pill retainer
Inventor: IWAKIRI TAKESHI
IPC: F16C11/06
Filed: 2007-12-04
Abstract: <P>PROBLEM TO BE SOLVED: To provide a spherical bearing excellent in durability.  <P>SOLUTION: The spherical bearing includes: a large ball 41; the spherical small ball retainer 42 consisting of an upper side bowl-like small ball retainer 42a and a lower side bowl-like small ball retainer 42b, with their top faces arranged oppositely; a plurality of small balls rotatably held by the spherical small ball retainer; and a housing 46 having a spherical cavity storing the spherical small ball retainer together with the plurality of small balls, and also having an opening at least in either one of the top and the bottom. The top face 43a of the upper side bowl-like small ball retainer and that 43b of the lower side bowl-like small ball retainer are joined via a joining means through a connecting means 47.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009094043-A (JP)
Title: Electrical appliance equipped with rotatable and acceptable plug
Inventor: TSAI SUNG-NIEN
IPC: H01R13/46
Filed: 2007-12-06
Abstract: <P>PROBLEM TO BE SOLVED: To provide an electrical appliance equipped with a plug that is rotatable and can be accepted.  <P>SOLUTION: The electrical appliance includes an upper case 100 and a lower case 400. The lower case 400 has two through-holes, two plug-receiving grooves 401 and two receptacles formed therein, and is engaged with the upper case 100. The electrical appliance further includes a plug having a first end part and a second end part. The first end part is inserted into the through-hole of the lower case. Furthermore, when the plug is rotated to a hidden position, the first end part of the plug is received by the plug-receiving groove of the lower case, while the second end part of the plug is received by the receptacle of the lower case. Furthermore, the electrical appliance includes a mounting member 200, that has two grooves formed there for the second end part of the plug to be inserted into and two clamps formed on the lower face for fixing the plug, and the circuit board mounted on the lower case 400.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009136902-A (JP)
Title: Pressure casting method of wheel for vehicle, device used for the same, and wheel material for vehicle
Inventor: SAKAMOTO HISAO
IPC: B22C9/28
Filed: 2007-12-07
Abstract: <P>PROBLEM TO BE SOLVED: To mold a wheel for a vehicle with high quality having no blowhole by pressure casting with high productivity even when the cross sectional area of a connection part for connecting an outer circumferential rim with the hub of a central part is small.  <P>SOLUTION: When casting the wheel for the vehicle having the hub 21 of the central part, the rim 22 of an outer circumferential part and the connection part 23 for connecting the hub 21 with the rim 22, a cavity 8 for molding the wheel in a posture which makes a wheel axis C almost horizontal is formed inside a molding die 1 that opens/closes in an almost horizontal direction. A molten metal 4 is pressurized and injected into the lowermost part 8d of a rim forming part 8a in the cavity 8, a pushing-in pin 7 is advanced from an axial direction to the central part of a hub forming part 8c in the cavity 8 at the midway of the solidification of the molten metal 4, and the solidification of the molten metal 4 is completed in such a state.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009143817-A (JP)
Title: Skin cleanser
Inventor: FUKUKITA YUKO
IPC: A61K8/34
Filed: 2007-12-11
Abstract: <P>PROBLEM TO BE SOLVED: To obtain a skin cleanser that has excellent usability, safety and cosmetic removal effect.  <P>SOLUTION: The skin cleanser comprises 0.1-20 mass% of a block type alkylene oxide derivative represented by general formula (I): R<SP>1</SP>O-(EO)<SB>a</SB>-(HO)<SB>x</SB>-(EO)<SB>b</SB>-R<SP>2</SP>(wherein EO is an oxyethylene group; HO is an oxyhexylene group; a+b and x are each an average addition molar number of an oxyhexylene group and an oxyhexylene group and 1≤a+b≤150 and 1≤x≤50; the addition forms of an oxyethylene group and an oxyhexylene group are in blocked form; the ratio of an oxyethylene group to the total of an oxyethylene group and an oxyhexylene group is 10-90 mass%: R<SP>1</SP>and R<SP>2</SP>may be the same or different and are each a 1-4C hydrocarbon group) and 0.1-20 mass% of a humectant.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009143051-A (JP)
Title: Ejection mechanism of injection molding machine
Inventor: HAZAMA SHUICHI
IPC: B29C45/40
Filed: 2007-12-12
Abstract: <P>PROBLEM TO BE SOLVED: To shorten cycle time during injection molding using a molding die that is ejected as a product part and a spool part of a molding are cut.  <P>SOLUTION: A gate-forming flow passage 31 of a movable die 9 is formed inward of a parting line PL of the movable die 9 and used as a submarine gate 24. A product-part ejection pin 33 and a spool-part ejection pin 34, both mounted to the movable die 9, are connected respectively to the piston rods 35a, 37a of first and second independent hydraulic cylinders 35, 37 so that the ejection pins 33, 34 operate independently of each other. The timing that the first hydraulic cylinder 35 ejects the product-part ejection pin 33 is made different from the timing that the second hydraulic cylinder 37 ejects the spool-part ejection pin 34, whereby the product part 16 and the spool part 17 of the molding 200 are discharged separately.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009145532-A (JP)
Title: Interchangeable lens barrel and camera system
Inventor: TAGUCHI FUMIYA
IPC: G02B7/02
Filed: 2007-12-13
Abstract: <P>PROBLEM TO BE SOLVED: To provide: an interchangeable lens barrel whose usability is improved; and a camera system.  <P>SOLUTION: The interchangeable lens barrel (100) includes: an electric element (120) that operates by receiving power; a power supply section (106) provided so as to supply power to the electric element; a connecting section (102) electrically connected to the main body (10) of the camera to receive power supplied from the main body of the camera; and a switching section (107) provided so as to switch between the supply of power from the power supply section to the electric element and the supply of power from the connecting section to the electric element.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009145621-A (JP)
Title: Toner and image forming method
Inventor: SUGAWARA NOBUYOSHI
IPC: G03G9/08
Filed: 2007-12-14
Abstract: <P>PROBLEM TO BE SOLVED: To provide toner and an image forming method, capable of outputting an image whose gray graininess is not prominent in a copying machine or a printer for which high precision image quality is required.  <P>SOLUTION: In the toner at least containing binder resin, a coloring agent and wax, the coloring agent at least contains carbon black and an inorganic pigment, the DBP adsorption quantity of the carbon black is 20-150g/100g, the number mean particle diameter of primary particle of the carbon black is 0.010-0.050 μm, the number mean particle diameter of the inorganic pigment is 0.020-1.000 μm, the refractive index of the inorganic pigment is 1.40-2.20, and when the primary particle diameter of the cabon black is A, the DBP adsorption quantity of the carbon black is B (g/100g) and the mean particle diameter of the inorganic pigment is C, the following expression is satisfied: 0.10≤10×A/äB×10<SP>(n×C)</SP>}≤0.65. The value of brightness L* in the powder state of the toner is 20<L*≤55, and the Hunter brightness W is 50-80.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009147717-A (JP)
Title: Image processing apparatus, and address change notification method
Inventor: IGARASHI MAROKI
IPC: H04L12/70
Filed: 2007-12-14
Abstract: <P>PROBLEM TO BE SOLVED: To provide an image processing apparatus and address change notification method in which even when a distribution address provided with a validity term is used as an address of the present apparatus itself, communication with a client can be continued.  <P>SOLUTION: The invention relates to the image processing apparatus 2 which communicates with a client 3, including: an address setting means 24 for setting a distributed distribution address as an address of the present apparatus itself; a recording means 25 for correspondingly holding a client address and the present apparatus address on an address correspondence table 21 when there is access from the client 3 to the present apparatus address; an address receiving means 22 for receiving a new distribution address from an address distribution device 1 before the validity term of the distribution address expires; and an address change notification means 23 for notifying, when the new distribution address is for updating the present apparatus address recorded on the address correspondence table 21, the client address corresponding to the present apparatus address about a change of the present apparatus address.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009151895-A (JP)
Title: Storage control device, image processing device, and program
Inventor: TSUTSUMI KENJI
IPC: G06F21/60
Filed: 2007-12-21
Abstract: <P>PROBLEM TO BE SOLVED: To execute overwriting a plurality of times on a plurality of areas where data are recorded, while reducing an area from which the data can be recovered with higher possibility.  <P>SOLUTION: A storage control device executes overwriting a predetermined number of times on a storage area where data have been recorded. The storage control device sets a remaining count indicating a difference between the predetermined number of times and the number of times of the overwriting in the storage area where overwriting has not yet been executed the predetermined number of times. The storage control device specifies the storage area having the maximum remaining count (Sa2) in the storage areas where data are recorded and the overwriting has not yet been executed the predetermined number of times and executes the overwriting once on the specified storage area (Sa3). The storage control device reduces the remaining count for each of the areas by "1" after the overwriting and repeats such processing until the remaining count becomes "0".  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009158990-A (JP)
Title: Antenna built-in vehicle exterior
Inventor: HIRAYAMA TOMIYASU
IPC: H01R4/64
Filed: 2007-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To easily mount an antenna built-in vehicle exterior to a body, and to reliably ground-connect an antenna in the antenna built-in vehicle exterior mounted to the outside of a vehicle.  <P>SOLUTION: An air spoiler 1000 having a hollow casing 2 includes: an antenna element that is mounted to the inside and connected to the conductor of a coaxial cable 15; a bracket 11 to which the shield wire of the coaxial cable 15 is connected; a bolt 11a for joining the bracket 11 to the body 1; and a collar 30 that is held between the bracket 11 and the body 1 and connects the bracket 11 to the body 1 electrically. The casing 2 of the air spoiler 1000 is provided at the fixed side to the body 1, and has a long hole 20p that has an internal diameter larger than that of the collar 30 and to which the bolt 11a is inserted, and nibs 20d, 20e, 20f, 20g for holding the bracket 11 at an area to the inner surface of the casing 2.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009156930-A (JP)
Title: Liquid crystal display unit
Inventor: HORII MASATOSHI
IPC: G02F1/1337
Filed: 2007-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To reduce light leakage along an edge portion of a pixel of a vertical alignment liquid crystal display unit.  <P>SOLUTION: A liquid crystal display unit has: a pair of opposing substrates; an electrode pattern formed on each of the substrates on an opposing surface side; a vertical alignment film formed on each of the substrates and covering the electrode pattern; a liquid crystal layer squeezed between the substrates; and a pair of polarizer plates which are formed on the substrates on an opposite side to the side of the liquid crystal layer and whose axial directions are crossed Nicols directions. The electrode pattern is composed of a segment electrode and a common electrode, an edge of the electrode pattern includes a zigzag pattern parallel or vertical to one of axial directions of the polarizer plates and an edge of a pixel defined by the segment electrode and the common electrode is parallel or vertical to the axial directions of the polarizer plates.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009154682-A (JP)
Title: Vehicle seat
Inventor: YAMAGISHI SUMIHIRO
IPC: B60N2/16
Filed: 2007-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To prevent a seat back from interfering with a seat cushion when the seat back rotates in a forward falling direction to have a forward-tilted position.  <P>SOLUTION: A vehicle seat includes a support base 4 which supports the seat back 2 against a floor F, and a front link 5 and a rear link 6 which pivotally couple the seat cushion 3 to the support base 4. A coupling shaft 6B being a coupling point between the rear link 6 to the seat cushion 3 is set at a position rearer than the coupling shaft 6A being the coupling point between the rear link 6 to the support base 4. The rear link 6 rotates in a direction for causing the coupling point to the seat cushion 3 to move downward by receiving power transmittance accompanying forward-falling rotation from the seat back 2.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009154754-A (JP)
Title: Optical axis adjusting device of vehicle headlamp
Inventor: NAKADATE KOICHI
IPC: B60Q1/115
Filed: 2007-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide an optical axis adjusting device of a vehicle headlamp for always holding the irradiation direction constant, even in acceleration and deceleration of an automobile.  <P>SOLUTION: This optical axis adjusting device 10 of the vehicle headlamp includes the vehicle headlamp 11 rockably supporting the optical axis in the vertical direction by a vehicle body front part of the automobile, a driving means 12 rocking the optical axis of the vehicle headlamp in the vertical direction, a vehicle height sensor 13 detecting the vehicle height of a vehicle body of the automobile, and a control part 14 driving and controlling the driving means so as to offset an inclination by arithmetically operating the inclination of the vehicle body of the automobile based on a detecting signal from the vehicle height sensor. The optical axis adjusting device 10 of the vehicle headlamp is constituted so that the control part drives and controls the driving means stepwise in response to vehicle information when an integral value of one vehicle information is a specific value or more in starting or deceleration of the automobile, and performs special correction control for rocking the optical axis of the vehicle headlamp stepwise in a plurality of predetermined angles.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009156375-A (JP)
Title: Twin clutch type speed-change apparatus
Inventor: TSUNASHIMA KOSUKE
IPC: F16H61/02
Filed: 2007-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide a twin clutch type speed-change apparatus, detecting an engagement state of a dog clutch, by using a rotational speed difference between an inner main shaft and an outer main shaft, and a signal output from a gear position sensor.  <P>SOLUTION: The rotational speed difference between an inner main shaft 7 and an outer main shaft 6 is detected by use of inner and outer rotational speed sensors 131, 132. When the engagement of the dog clutch is to be released, it is determined to complete the release if the signal output from the gear position sensor 134 indicates a speed step number after shifting and the rotational speed difference is zero. It is determined as a dog-end caught state if the signal output from the gear position sensor 134 indicates a speed step number before or after shifting and the rotational speed difference is a transmission gear ratio difference. When the dog clutch is engaged, it is determined to complete the engagement if the signal output from the sensor 134 indicates a speed step number after shifting and the rotational speed difference is a transmission gear ratio difference between before and after shifting. It is determined as a dog-end abutting state if the rotational speed difference is equal to or less than a transmission gear ratio difference before and after shifting.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009163903-A (JP)
Title: Vehicle lamp
Inventor: ASADA TAKESHI
IPC: F21S2/00
Filed: 2007-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To achieve a vehicle lamp capable of effectively suppressing the occurrence of resonance of air vibration (so-called piping sound) due to steady-state vortices generated at a stepped part or a corner part.  <P>SOLUTION: For the vehicle lamp 4 equipped at a front part of the vehicle, a stepped part PL or a corner part is formed at an outer periphery edge part 22 of a lens 20, and at the same time, a gap D opened outward is formed between the outer periphery edge part 22 of the lens 20 and a lens support part 12 of a housing 10, and further, minute rugged parts 13 are formed at a part of the lens support part 12 of the housing 10 opposed to the gap D.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2008178974-A (JP)
Title: Holding device, aligning device provided with holding device, storing device and holding method
Inventor: KANETANI MASATOSHI
IPC: B65B35/36
Filed: 2007-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a holding device capable of holding end parts of an object to be held from the front and rear sides, even if the holding device is arranged at an upper position of the object to be held.  <P>SOLUTION: This hand (holding device) 30 holds a sheet member (object to be held) 2 by a pair of first holding surface 31a and second holding surface 32a. The second holding surface 32a is turned from the outside position of an outer edge part 2t of the sheet member 2 to the inside position, and is faced to the first holding surface 31a to hold the sheet member 2 in the radial direction at the inside position and is located at a saving position which does not overlap with the first holding surface 31a in the radial direction at the outside position, in relation to a turning circle S2 of the second holding surface 32a.  <P>COPYRIGHT: (C)2008,JPO&INPIT
Patent JP-2008179814-A (JP)
Title: Composition
Inventor: HODGSON THOMAS CLARENCE
IPC: C08L97/02
Filed: 2007-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a binder to be used in a sheet composition and a sheet composition product.  <P>SOLUTION: This is a method for producing the composition product comprising a substrate material and the binder in which the binder contains an emulsified plastic material or is prepared by adding a plastic material to the emulsion including the substrate material. In addition, the invention relates to the composition product comprising a granular substrate and a granular plastic material.  <P>COPYRIGHT: (C)2008,JPO&INPIT
Patent JP-2007527460-A (JP)
Title: エチレンコポリマー変性配向ポリプロピレン
IPC: C08K3/26
Filed: 2005-03-04
Abstract: （ａ）少なくとも一種のポリプロピレンポリマーと；（ｂ）少なくとも一種のエチレンコポリマー、例えばエチレン／酢酸ビニルジポリマー、エチレン／酢酸ビニルターポリマー、エチレン／（メタ）アクリル酸アルキルジポリマー、エチレン／（メタ）アクリル酸アルキルターポリマー、官能化エチレンコポリマー、エチレン／酸コポリマーおよびそれらの塩を含んでなる組成物から調製された配向フィルム、テープおよび溶融紡糸繊維を開示する。このフィルム、テープおよび繊維は、未変性ポリプロピレン組成物と比較して改善された引張強度および破断点伸びなどの引張特性を示す。また記載された配向溶融紡糸繊維から調製された織物、不織物および編物材料、ならびに本発明のスリットフィルム繊維の製造方法も開示する。
Patent JP-2007529181-A (JP)
Title: マルチモード／マルチバンド移動局及びその移動局の動作方法
IPC: H04W88/02
Filed: 2005-03-15
Abstract: マルチモード/マルチバンド移動局及びその移動局の動作方法を提供する。マルチモード/マルチバンド移動局は、マルチモード/マルチバンド信号をそれぞれの送信器を通じて送信する送信部と、マルチモード/マルチバンドのうちの同一の周波数帯域に該当する信号は、同一の周波数帯域のサービスが異なる一つ以上の無線信号を共に受信する兼用受信器を通じて受信し、同一の周波数帯域に該当しない信号は異なる周波数帯域別受信器を通じて受信する受信部と、を含むことを特徴とする。本発明によるマルチモード/マルチバンド移動局は、同一の周波数帯域に対してサービス形態が異なっても一つの兼用受信器を使用することによって受信器の個数を減少することができる。また、マルチモード/マルチバンド移動局は、従来のＦＤＤ方式(例えば、ＷＣＤＭＡ方式)のデュプレクサをＴＤＤ方式(例えば、ＧＳＭ８５０又はＰＣＳ１９００方式）にも使用可能である。
Patent JP-2007527982-A (JP)
Title: 流体圧サービス・モジュール
IPC: F15B21/0423
Filed: 2005-03-08
Abstract: 適切な量の流体圧流体を貯蔵するための流体リザーバーを含む、流体圧サービス・モジュール（４４）が流体圧流体システム用に設けられる。この流体圧サービス・モジュールは、その中に周囲空気と流体連通する空気チャンバ（５４）を含む筐体を画成する外側ケーシング（４６）を備える。この流体圧サービス・モジュールは、前記筐体内に取付けられる１つまたは複数の流体圧力アキュムレータ（４８）および前記流体圧流体を冷却するために設けられる熱交換器（６４）とを格納する。
Patent JP-2007530808-A (JP)
Title: 脂肪および油に対する高い浸透抵抗を有する紙材およびその製造方法
IPC: D21H17/16
Filed: 2005-03-31
Abstract: 技術水準で知られた種々の紙材は脂肪に対する平凡な耐性のみを示すかまたは脂肪および油の浸透に対する高い耐性を示すために、塊または含浸液の形でフルオロカーボン化合物またはクロム化合物を含有する。これらのフッ素化合物またはクロム化合物は健康に有害であることが知られているかまたは少なくとも重大な疑いがある物質である。従って本発明の課題は健康に有害な成分を含まず、同時に脂肪および油の浸透に対する高い耐性が備えられ、容易に印刷することができ、再利用可能である紙を作成することである。前記課題は、完全粉砕繊維材料から製造され、製紙機の内部または外部で、ポリビニルアルコール、エチレン−ビニルアルコールコポリマー、ポリビニルブチラール、カルボキシメチルセルロース、ゼラチン、アルギネート、ガラクトマンナン、澱粉誘導体を含有する含浸液で含浸する間に塊の形のアルケニル無水コハク酸でサイズ処理された紙を使用することにより脂肪および油の高い浸透抵抗が得られ、その際ポリビニルアルコールおよびゼラチンが有利である。
Patent JP-2007531804-A (JP)
Title: 接着促進化合物
IPC: C07F9/11
Filed: 2005-03-17
Abstract: 本発明は、印刷インク用の接着促進剤と該接着促進剤を含む印刷インクとを含む。接着促進剤は、（ａ）ポリマー又は合成樹脂の溶液を有機リン化合物と一緒に混合し、そして（ｂ）（ａ）で形成された混合物を、チタンのハロゲン化物、アルコキシド、ハロ−アルコキシド又は縮合チタンアルコキシド又はこれらのチタン化合物の二つ以上の混合物から選ばれるチタン化合物と混合した生成物を含む。
Patent JP-2007531447-A (JP)
IPC: H03M1/00
Filed: 2005-03-23
Abstract: In a digital to analogue converter, a plurality of digital inputs are used to select one of first and second binary voltage levels as binary inputs (10) to the converter. A capacitor circuit (C, 2C, . . . , 32C) is associated with each input, and these are controlled to output an effective voltage to an output load comprising the first binary voltage level, the second binary voltage level or an average of the first and second binary voltage levels in dependence on the bits of the digital input word. The plurality of capacitor circuits can be operated in either a voltage divider mode (to provide an average output) or a resistor mode depending on the value of the digital data. Operation of the capacitor circuits in this way can result in a reduction in the currents flowing and can therefore reduce the power consumption.
Patent JP-2007532650-A (JP)
Title: プロリンｃｃｉ−７７９（２，２−ビス（ヒドロキシメチル）プロピオン酸とのプロリン−ラパマイシン４２−エステル）ならびに細菌リパーゼを使用するプロリンｃｃｉ−７７９およびｃｃｉ−７７９の二段階酵素的合成
IPC: C07F7/18
Filed: 2005-04-12
Abstract: ２，２−ビス（ヒドロキシメチル）プロピオン酸とのプロリン−ラパマイシン４２−エステル（プロリン−ＣＣＩ−７７９）、ならびに（ａ）構造（Ａ）［この構造中、Ｒ 1 およびＲ 2 は、水素であり、または一緒になって構造（Ｂ）（この構造中、Ｒ 3 およびＲ 4 は、各々独立して、水素または線状もしくは分枝状Ｃ 1 〜 6 アルキルである）を形成し、または一緒になってＣ 5 〜 7 シクロアルキルを形成し、または一緒になって構造（Ｃ）（この構造中、Ｒ 5 は、メチル、エチル、ｎ−プロピル、イソプロピル、ｎ−ブチル、イソブチルおよびフェニルから選択される）を有する環状ボロネートを形成する］を有する２，２−ビス（ヒドロキシメチル）プロピオン酸の活性化エステル誘導体とラパマイシンまたはプロリン−ラパマイシンとを適する有機溶媒中、有効量の細菌リパーゼの存在下で反応させる段階、ならびに（ｂ）段階（ａ）から得られた中間体を脱保護して、ＣＣＩ−７７９またはプロリン−ＣＣＩ−７７９を生じさせる段階を含む、２，２−ビス（ヒドロキシメチル）プロピオン酸とのラパマイシン４２−エステルまたは２，２−ビス（ヒドロキシメチル）プロピオン酸とのプロリン−ラパマイシン４２−エステル（ＣＣＩ−７７９およびプロリン−ＣＣＩ−７７９）の位置特異的調製方法を開示する。