baber/WOPTO huggingface dataset:
Patent IL-195181-A (IL)
Title: Compositions for inhibiting the expression of the pcsk9 gene
IPC: C12N15/113
Filed: 2008-11-09
Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a human PCSK9 gene in a cell, wherein said dsRNA comprises at least two sequences that are complementary to each other and wherein a sense strand comprises a first sequence and an antisense strand comprises a second sequence comprising a region of complementarity which is substantially complementary to at least a part of a mRNA encoding PCSK9, and wherein said region of complementarity is less than 30 nucleotides in length and wherein said dsRNA, upon contact with a cell expressing said PCSK9, inhibits expression of said PCSK9 gene, wherein (a) said first sequence is the sequence of SEQ ID NO: 1229 and said second sequence is the sequence of SEQ ID NO: 1230; (b) said first sequence is the sequence of SEQ ID NO: 1227 and said second sequence is the sequence of SEQ ID NO: 1228; or (c) said part of said mRNA encoding PCSK9 is the sequence from position 3530 to 3548 of the mRNA sequence of database entry NM_174936.
Patent IL-195892-A (IL)
Title: Use of isatx247, vitamin e tpgs, mct oil, an emulsifier and ethanol in the preparation of a pharmaceutical composition
IPC: A61K9/10
Filed: 2008-12-11
Abstract: The present invention relates to formulations containing cyclosporin analogs that are structurally similar to cyclosporin A, in particular isomeric mixtures of cyclosporin analogs that are structurally similar to cyclosporin A. The formulations form stable microemulsion preconcentrates and may provide superior drug bioavailability and/or may reduce one or more adverse effects associated with the administration of cyclosporin. Also disclosed are methods for using and preparing the formulations.
Patent IL-203968-A (IL)
Title: Photodamage modulator for treating uv photodamage
IPC: A61K8/00
Filed: 2010-02-15
Abstract: The invention relates to methods for modulating photodamage via the use of collagen derived molecules which either enhance or inhibit damage caused by ultraviolet light.
Patent JP-H07304060-A (JP)
Title: Multistage filling type injection molding method
Inventor: NAGASAKA MASAHARU
IPC: B29C45/14
Filed: 1994-05-13
Abstract: PURPOSE:To dispense with a resin material re-filling process (post process) for eliminating the residual shape of a support pin. CONSTITUTION:In injection molding for producing a resin product 9 having an insert member 4 consisting of a different kind of materials embedded therein, a mold structure having the support pin 5 setting the insert member 4 at a predetermined position of a product cavity 3 and the drive means 6 rearwardly driving the support pin 5 in the axial direction thereof is used. An injection molding method consists of a process allowing the tip part 5a of the support pin 5 to protrude to the product cavity 3 and setting the insert member 4 to the tip part 5a, a process retracting the support pin 5 by the drive means 6 after the elapse of a predetermined period predetermined on the basis of the solidifying characteristics of the resin material 10 charged in the product cavity 3 to form a space 11 between the insert member 4 and the tip part 5a of the support pin 5 and a process filling the space 11 with the resin material.
Patent JP-H01272147-A (JP)
Title: Semiconductor device and manufacture thereof
Inventor: OTSUKA FUMIO
IPC: H01L27/092
Filed: 1988-04-25
Abstract: PURPOSE:To ensure the breakdown strength of an n-channel MISFET by making an insulating film on the sidewall of a p-channel MISFET smaller than that on the sidewall of the n-channel MISFET in a semiconductor integrated circuit device with a CMOS adopting LDD structure. CONSTITUTION:Length in the channel length direction of a semiconductor region 18 is constituted in size smaller than semiconductor regions 9 in a MISFETQn and a MISFETQS. That is, a sidewall insulating film 19 is organized so that length in the channel length direction is made smaller than a sidewall insulating film 16 in the MISFETQn and a sidewall insulating film 10 in the MISFETQS. The sidewall insulating film 19 is constructed in size smaller than 0.3mum such as 0.1mu-0.25mum on a 1.3mum process. That is, since the series resistance value of a semiconductor region (between a source region and a drain region) 20 can be lowered, current driving force can be increased while a section (between a source region and a drain region) between semiconductor regions 17 can be isolated, thus ensuring breakdown strength between the semiconductor regions 17.
Patent JP-S58216942-A (JP)
Title: Detection of cracking speed for steel material
Inventor: TSUKAMOTO MASATOSHI
IPC: G01N25/72
Filed: 1982-06-11
Abstract: PURPOSE:To determine the crack propagation velocity from time lag in temperature changes of thermocouples and the interval of thermocouple mounting positions by detecting the temperature changes when a steel material is ruptured with the thermocouples on the crack propagation path thereof. CONSTITUTION:A side groove 11 is provided on a sample 1 as steel material to create a crack propagation path. The side groove 11 with a V-shaped cross-section gives the width W=5.18mm., the depth d=6.25mm. and the angle Q=45 deg.. Thermocourles C1, C2...Ci are applied on the bottom of the side groove 11 at specified intervals DELTAl1, DELTAl2...DELTAli. Temperature detected with thermocouples is sent to an amplifier and then to a waveform memory to memorize. Outputs of the thermocouples memorized are taken out delayed in the time range to determine the crack propagation velocity V=DELTAt/DELTAl from a time lag DELTAt in the output changes of the thermocouples and the interval DELTAl of the thermocouple mounting positions.
Patent JP-S5223907-A (JP)
Title: Tape driving unit
Inventor: KAWASAKI ITARU
IPC: G11B15/46
Filed: 1975-08-18
Abstract: PURPOSE: By two capstans which differ slightly in speed, a magnetic tape shall be run and driven stable. 
     COPYRIGHT: (C)1977,JPO&Japio
Patent JP-S5528707-A (JP)
Title: Filter cloth for bag filter
Inventor: INDOU KENJI
IPC: B01D39/16
Filed: 1978-08-18
Abstract: PURPOSE: To obtain the filter cloth for back filters which permits high speed filtration, permits dust shaking-off of reverse pressure or reverse pressure pulsation system by low pressure, provides high dust collecting efficiency and is adaptable even to large-size dust collectors.  
     CONSTITUTION: Cotton form synthetic fibers 2 composed primarily of, e.g., polyester, are provided as web on both sides of a core base cloth 1 as a center and are compression bonded into the foregoing base cloth 1 through punching by needles. The synthetic fiber non-woven fabrics, for which ones of size 0.5 to 1.5 deniers are used, are compression bonded and formed to the core base cloth at METSUKE weight 350 to 450g/cm 2 , thickness 0.8 to 1.2mm, mean pore diameter 10 to 20μm, voides 70 to 70%, air permeability 10 to 15cc/cm 2 , sec., and the surfaces thereof are smoothed. 
     COPYRIGHT: (C)1980,JPO&Japio
Patent JP-S60243406-A (JP)
Title: Kerosene combustion apparatus
Inventor: TOMIZAWA TAKESHI
IPC: F23D3/10
Filed: 1984-05-18
Abstract: PURPOSE:To make possible an effective radiation heating by providing a high temperature radiation body at a range of a combustion and a low temperature radiation body at a downstream side of a combustion. CONSTITUTION:A front upper multihole plate 10 is brought to a red heated state during a constant combustion and heat rays are emitted through a window 11. Further, an unburned fuel is burned perfectly by a secondary air which is supplied from secondary air ports 15, 16, and exhaust gas is exhausted from a flue to an outside of a apparatus passing through an exhaust gas outlet opening 23. The heat, which is retained still sufficiently in exhaust gas, is exchanged heat by the heat exchange fin 21 of the flue 19 and conducted to the upper section 18a of an external cylinder, and the heat rays are emitted from the sufficiently temperature rised outside of said upper section and the external fin 20 outwardly. In this manner, the red heated front upper multiplate 10 is changed into the high temperature radiation body, especially the upper section 18a of the external cylinder 18 is changed into the low temperature radiation body, and an amount of the radiation for the apparatus is improved.
Patent JP-H04333781-A (JP)
Title: Air tent medical facility
Inventor: SAITO KENICHIRO
IPC: E04H3/08
Filed: 1991-05-02
Abstract: PURPOSE:To install an emergency medical facility speedily to cope with calamities by making the inside of a tent as positive pressure, and providing a demarcation medical unit inside the air-tent preventing the incursion of polluted air from the outside. CONSTITUTION:The inside of a tent is in a state of positive pressure, and a demarcation medical unit is provided to the inside of the tent preventing the incursion of polluted air from the outside. A HEPA filter 2, etc., are mounted to an intake side of an air tent blower 1. If necessary, an air conditioner 9 and/or an air cleaner, etc., are arranged to the demarcation medical unit. An air curtain is provided to a doorway 10 provided to an appropriate position, and it is desirable that the air tent is separated from the outside.
Patent JP-H07124129-A (JP)
Title: Circulatory organ function measuring instrument
Inventor: SHIMIZU MASAFUMI
IPC: A61B5/0245
Filed: 1994-05-16
Abstract: PURPOSE:To measure the dynamical characteristics of the artery with a high accuracy in non-invasion and non-blood observation fashion by pressing the artery of a living body local part by a cuff, and calculating pressure-content volume characteristics by detecting cuff pressure and pulse wave amplitude in a process to increase/decrease pressure. CONSTITUTION:This measuring instrument is provided with the cuff 1 mounted on a specific part of a living body and pressing the artery, and a pressure control means consisting of a pressurizing pump 2 to increase/decrease the pressure of the cuff and an exhaust valve 3. Furthermore, a pressure sensor 4 is provided with an amplifier 5 which detects the pressure inside the cuff and amplifies detected pressure, and an A/D converter 6 which converts the output of the amplifier to a digital value. A CPU 7 detects and samples an artery component synchronized with a heartbeat caused from the change in an artery content volume in a process to increase/decrease a pressure gradually by the pressure control means, and calculates the amplitude every pulse of a pulse wave, and also, detects the pressure inside the cuff when the pulser wave appears. Also, a pressure-content volume characteristics estimating means to estimate the pressure-content volume characteristic of the artery based on the pulse wave amplitude and pulse wave correspondence cuff pressure is provided.
Patent JP-2000287504-A (JP)
Title: Speed-changing device of agricultural working machine
Inventor: OTA KAZUYOSHI
IPC: A01B33/08
Filed: 1999-04-08
Abstract: PROBLEM TO BE SOLVED: To allow the transmission of power to be readily changed from a driving shaft to a following shaft in an agricultural working machine for carrying out a plowing operation or a mowing operation by normally or reversely rotating a rotary operating part. SOLUTION: A change gear box 4 has a driving shaft 24 for receiving power from a PTO shaft of a tractor and a following shaft 25, arranged in the front and rear direction in parallel, and change gears 26 and 28 are installed in the rear end sides of both the shafts 24 and 25 so as to be insertable and replaceable.  Further, an idling gear 31 is installed in the rear end sides of both the shafts 24 and 25 and the front sides of the gear widths of the change gears 26 and 28 in the agricultural working machine attached to the rear part of a tractor through a three-point link hitch structure so as to be freely lifted and lowered, and for carrying out the plowing operation or mowing operation by normally or reversely rotating a rotary operating part having many plowing or mowing blades arranged around a horizontally extended rotary shaft by receiving the power from the PTO shaft of the tractor to the change gear box 4. The power is transmitted from the driving shaft 24 through the idling gear 31 to the following shaft 25, or transmitted from the driving shaft 24 to the following shaft 25 by directly engaging both the change gears 26 and 28 by replacing the change gears 26 and 28.
Patent JP-S63267189-A (JP)
Inventor: SEKI MAKI
IPC: G05B19/4093
Filed: 1987-04-25
Abstract: (57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。
Patent JP-H05297733-A (JP)
Title: Image forming device
Inventor: FUMA HIROSHI
IPC: G03G15/01
Filed: 1992-04-21
Abstract: PURPOSE:To provide an inexpensive image forming device provided with a transfer belt device. CONSTITUTION:In the image forming device which is provided with a PCL, a scorotron electrifier, a laser writing device, a plurality of developing units, the transfer belt device 30, a cleaner, etc., around the periphery of a photosensitive drum 10 as an image carrier and which forms a multicolor toner image by repeating an electrification/image exposure/development process to superimpose toner images on the photosensitive drum 10, the transfer belt device 30 divides the output of a high voltage power source 41, which supplies a bias voltage to a transfer unit 36, by means of two resistors R1 and R2, thereby supplying the recording sheet electrification bias voltage to be applied to a holding roller 32 to attract the recording sheet P to a transfer belt 31.
Patent JP-H06308568-A (JP)
Title: Stroboscopic exposure photometric device
Inventor: MORI KEIICHI
IPC: G03B7/16
Filed: 1993-04-27
Abstract: PURPOSE:To detect a difference between an optimum exposure level and a stroboscopic exposure level on an APEX calculation when it is impossible to control light at stroboscopic photographing. CONSTITUTION:In a single-lens reflex camera capable of using a stroboscopic device which can emit flash light, reflected light from a film surface, or the front curtain of a shutter is received by a photoelectric conversion part 1. The output from the photoelectric conversion part 1 is integrated by an integration part 2, and the integrated output is compressed and transformed logarithmically by a logarithmical compression and transformation part 3 functioning as a 1st transformation part. A prescribed level is set by a decision level generating part 4 based on a film sensitivity, and the output from the decision level generating part 4 is compressed and transformed logarithmically by a logarithmically compression and transformation part 5 functioning as a 2nd transformation part. The subtraction of the output from the logarithmical compression and transformation part 3 and the output from the logarithmical compression and transformation part 5 is executed by a subtraction part 6 so as to obtain an output showing a deviation from the optimum exposure when the flash light is emitted by the stroboscopic device.
Patent JP-H10291297-A (JP)
Title: Intaglio printer
Inventor: SCHAEDE JOHANNES
IPC: B41F11/02
Filed: 1998-04-13
Abstract: PROBLEM TO BE SOLVED: To provide an intaglio printer having low manufacturing and installing costs and considerably low bulk. SOLUTION: The intaglio printer comprises a main structure 6, a plate cylinder 4, an impression cylinder 3, a wiping unit 10 and an ink facility. The facility has a capturing ink cylinder 5, at least four color selecting cylinders 7a to 7d, and inking units 8a to 8d provided at a movable ink conveyor 9 cooperative with the cylinders 7a to 7d. A ratio of diameters of both the cylinders 5, 4 is equal to 2/3. A sidewall of the conveyor 9 is provided at the same side as the cylinders 7a to 7d to form recesses. The recesses are formed in size to completely contain the cylinders 7a to 7d in the recesses so that the cylinders 7b, 7c between the cylinders 7a and 7d are completely contained in a space of the recess while the conveyor 9 is disposed at the operating position.
Patent JP-S63266325-A (JP)
Title: Force detector
Inventor: OKADA KAZUHIRO
IPC: G01L5/16
Filed: 1987-04-24
Abstract: PURPOSE:To simplify the structure, and also, to execute the measurement with high accuracy by detecting the force working on a strain-generating body, as the resistance variation of a resistance element. CONSTITUTION:On a single crystal substrate 10 of silicon, resistance elements RX1-RX4, RY1-RY4 and RZ1-RZ4 having total 12 pieces of piezo-resistance effects are formed. The resistance elements RX1-RX4 are used for detecting the force in the X axis direction, the resistance elements RY1-RY4 are used for detecting the force in the Y axis direction, and the resistance elements RZ1-RZ4 are used for detecting the force in the Z axis direction. This single crystal substrate 10 is stuck to a strain-generating body 20, and the force working on this strain generating body 20 is detected as a resistance variation of the resistance elements RX1-RX4, RY1-RY4, and RZ1-RZ4.
Patent JP-S5528451-A (JP)
Title: Preparation of heat transfer surface
Inventor: FUJII MASAO
IPC: F28F13/02
Filed: 1978-08-19
Abstract: PURPOSE: To easily obtain this porous heat transfer surface with excellent heat transfer characteristics, by sticking particles on a surface of the heat transfer surface by maintaining magnetic substance particles on the heat transfer surface by magnetic force and by forming a metallic film by means of a method such as plating.  
     CONSTITUTION: A magnetic field is made up to a surface, which contacts with a boiling liquid, from the back, which does not contact with said liquid, of a heat transfer substrate 2 by means of a method, such as, a permanent magnet, etc., and the substrate is soaked in a plating liquid under a condition that the particles 7 of a magnetic substance with an arbitrary shape are maintained on the surface of the heat transfer substrate 2 and copper plated, thus building up a metallic film 8 of copper. Thus, this porous heat transfer surface 4 is obtained by sticking the magnetic substance particles 7 on the heat trnasfer substrate 2. Consequently, this heat transfer surface can easily be formed which can excellently transfer heat to the boiling liquid contacted with the heat transfer surface 4 side. 
     COPYRIGHT: (C)1980,JPO&Japio
Patent JP-S5625958-A (JP)
Title: Electroless nickel plating method for high nickel chromium alloy
Inventor: TAKIZAWA YOSHIO
IPC: C25D3/12
Filed: 1979-08-10
Abstract: PURPOSE: To carry out electroless Ni plating with high adhesion by striking a high Ni.Cr alloy with Ni and activating the struck surface.  
     CONSTITUTION: A high Ni.Cr alloy is pretreated by degreasing and pickling and struck with Ni. The struck Ni surface is then activated by acid treatment with a strong acid such as a soln. of nitric acid and hydrofluoric acid, and immediately after washing, electroless Ni plating is carried out. In place of the acid treatment activation, the struck alloy may be subjected to electrolytic elution as an anode in an Ni plating bath at relatively low current density to obtain similar effect. 
     COPYRIGHT: (C)1981,JPO&Japio
Patent JP-S5434834-A (JP)
Title: Electrophotographic method
Inventor: NAMIKI RIYOUICHI
IPC: G03G13/16
Filed: 1977-08-24
Abstract: PURPOSE: To improve the transfer rate, separation rate, etc. of printing by controlling electrostatic charge quantity for transfer paper based on the water content of transfer paper in an electrophotographic copying method. 
     COPYRIGHT: (C)1979,JPO&Japio
Patent JP-H02218642-A (JP)
Title: Prostaglandin
Inventor: ROBAATO RESURII JIYOONZU
IPC: C07D493/08
Filed: 1989-04-19
Abstract: NEW MATERIAL: A compd. represented by formula I (a group represented by formula II is divalent cyclic groups represented by formulae III-VII, R 1  is 6- carboxyhexa-2-enyl or a modified group modified by the reduction of a double bond voluntarily accompanied by the substitution of C-atoms at a first position- third position by S or O (i), the conversion of the position of a double bond (ii), the shortening or extension of a carbon chain by 1-2 CH 2  (iii) and either one of treatments forming amide or ester of carboxy or a salt derived group (iv), R 2  is an aliphatic hydrocarbon group substituted by an aliphatic hydrocarbon group and an aromatic group directly or through O or S and V and W are combined to form O of carbonyl or V is H and W is OH).  
     USE: An intermediate useful for synthesizing prostaglandins having various types of ring systems.  
     PROCESS: For example, a compd. represented by formula VIII is reacted with a Grignard reagent [R 2 Mg (halogen)] to obtain secondary alcohol represented by formula ix and this alcohol is reacted with a Jones reagent to obtain the compd. represented by formula I. 
     COPYRIGHT: (C)1990,JPO
Patent JP-S583079-A (JP)
Title: Processing system for division to character unit and extraction of character
Inventor: SHIMIZU SHINICHI
IPC: G06K9/62
Filed: 1981-06-30
Abstract: PURPOSE:To divide characters correctly, by extracting character stroke projection vectors and pen movement vector projections to compare and discriminate them and discriminating pen movement places which are not placed for division to character units. CONSTITUTION:A generating part 8 for projection vectors of character strokes traces X coordinate values out of a column of coordinate values of points on a character stroke in the direction of xi. A pen movement vector extracting part 9 extracts a vector, which is started at coordinates of the end point of the first character stroke and is terminated at coordinates at the start point of the second character stroke, to extract pen movement vectors. A generating part 10 for projection vectors of pen movement vectors extracts X coordinate values in rspect to extracted pen movement vectors to obtain the magnitude and the direction of the projection vector of a pertinent pen movement vector. Condition discriminating parts 12-14 discriminate correct division places on a basis of these results.
Patent JP-S60255127-A (JP)
Title: Filter unit
Inventor: MARIA KURISUCHINA KANTONI
IPC: B01D46/12
Filed: 1985-05-15
Abstract: A multiple filter unit (10) in the form of a complete interchangeable unit for insertion into a motor vehicle interior ventilation duct (7), or into the mouth of air conditioners or into suction-producting apparatus for closed environments, comprising a rigid casing (11) provided with retention and sealing means (12), a series of filter elements and/or chemical products (13, 15 to 18) and/or electrostatic filtering devices disposed in a predetermined order for filtering solid particulate matter, mists and air pollutant gases, and means (13a, 15a to 18a or 21, 22) for checking the degree of efficiency.
Patent JP-H11281886-A (JP)
Title: Optical device and automatic focusing camera
Inventor: NAKANO SHINGO
IPC: G03B13/02
Filed: 1998-03-31
Abstract: PROBLEM TO BE SOLVED: To prevent a focusing action from becoming unfeasible in a short time by executing a searching action executed when the focus of a selected focus detection point cannot be detected after the elapse of the prescribed time after a focus detection unfeasible state is detected and making the selected focus detection point face to a focus detection object within the prescribed time. SOLUTION: The deviation amount and the contrast of two images are obtained from two set of image signals stored in a RAM (#22). When the contrast of two images are lower than a prescribed value, a 300 msec-timer is started (#27), a focus detecting action is started and the image signals of two images are stored in the RAM (#28). Next, the deviation amount of two images is obtained and the contrast of two images are also calculated (#29). Based on the contrast of two images, it is discriminated whether the focus can be detected or not (#30). When the focus cannot be detected, the state of the timer is confirmed (#31). When time-up is attained, the searching action is executed (#32). Thereafter, a lens is driven (#25).