baber/WOPTO huggingface dataset:
Patent AT-E444080-T1 (AT)
Inventor: GREENWALD RICHARD
IPC: A61K45/00
Filed: 1998-12-14
Granted: 2009-10-15
Abstract: The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric prodrugs are preferably of formula (I) wherein: L 1  is a bifunctional linking moiety; in formula (a) B is H, a leaving group, a residue of an amine-containing moiety, or a residue of a hydroxyl-containing moiety; Y 1-4  are independently O. S, or NR 12 ; R 1 , R 4 , R 9 , R 10  and R 12 , are independently selected from the group consisting of hydrogen C 1-6  alkyls, C 3-12  branched alkyls, C 3-8  cycloalkyls, C 1-6  substituted alkyls, C 3-8  substituted cycloalkyls, aryls, substituted aryls, aralkyls, C 1-6  heteroalkyls, substituted C 1-6  heteroalkyls; R 2 , R 3 , R 5  and R 6  are independently selected from the group consisting of hydrogen, C 1-6  alkyls, C 1-6  alkoxy, phtnoxy, C 1-8  heteroalkyls, C 1-8  heteroalkoxy, substituted C 1-6  alkyls, C 3-8  cycloalkyls, C 3-8  substituted cycloalkyls, aryls, substituted aryls, aralkyls, halo-, nitro-, cyano-, carboxy-, C 1-6  carboxyalkyls and C 1-6  alkyl carbonyls; Ar is a moiety which when included in Formula (I) forms a multi-substituted aromatic hydrocarbon or a multi-substituted heterocyclic group; (m), (r), (s), (t), (u) and (v) are independently zero or one; (p) is zero or a positive integer, and R 11  is a substantially non-antigenic polymer. The first prodrug is generated when the polymeric portion of the double prodrug is cleaved and the parent molecule is generated rapidly thereafter  in vivo,  preferably as a result of a 1,6 or 1,4 benzyl elimination-reaction. Methods of preparing the compounds and methods of treatment are also disclosed.
Patent AT-E291478-T1 (AT)
Inventor: EKBERG BJARNE
IPC: F26B3/24
Filed: 1999-06-04
Granted: 2005-04-15
Abstract: The invention relates to a method for making the drying of materials, particularly finely divided materials, more effective in a suction drier provided with a fine porous suction surface, where the radii of the fine pores of the suction surface are essentially within the range of 0.5 - 2 micrometers, and in which method, of a slurry containing liquid and solids there is made a filter cake (2,12,22) onto the fine porous liquid suction surface constituting the filter surface of the filter medium (1,11,21), According to the invention, the filter cake (2,12,22) and the oscillator (6,15,25) are arranged, in relation to each other, so that in between the filter cake (2,12,22) and the oscillator (6,15,25), there is generated an acoustic field by virtue of a mechanical contact between the filter cake (2,12,22) and the oscillator (6,15,25) or a structural element (7,16,26) connected to the oscillator. <IMAGE>
Patent AT-E290555-T1 (AT)
Inventor: YU POLI C
IPC: C09K3/10
Filed: 1999-12-10
Granted: 2005-03-15
Abstract: The present invention relates to aqueous solutions or dispersions of compositions containingA) compounds, which contain 0.5 to 15% by weight of alkoxysilane and/or silanol groups (calculated as Si, MW 28), based on the weight of the compounds containing alkoxysilane groups, and are substantially free from isocyanate groups and chemically incorporated hydrophilic groups, wherein the alkoxysilane groups are initially incorporated by the reaction of a polyisocyanate with an amino compound corresponding to formula I whereinX represents identical or different organic groups which are inert to isocyanate groups below 100°C, provided that at least one of these groups is an alkoxy group,Y represents a linear or branched alkylene group having 1 to 8 carbon atoms andR<sub>1</sub> represents an organic group which is inert to isocyanate groups at a temperature of 100°C or less, andB) 1 to 20% by weight, preferably 1 to 15% by weight and most preferably to 2 to 10% by weight of colloidal silica, based on weight of the compounds containing alkoxysilane groups.The present invention also relates to coating, adhesive or sealing compositions containing these aqueous compounds as the binder.
Patent AT-E235124-T1 (AT)
Inventor: DALLA PIAZZA SILVIO
IPC: H03B5/36
Filed: 1999-12-21
Granted: 2003-04-15
Abstract: The oscillator device for low frequency comprises a quartz-crystal resonator (1) and an electronic circuit for maintaining the oscillations of resonator. The quartz-crystal resonator has a unique angle of section defined by an angle (theta) of rotation around the crystallographic axis (x) of quartz-crystal, so that the resonator has at least one fundamental mode of vibration in flexion at a first frequency, and a desired fundamental mode of vibration in torsion at a second frrequency, which is higher than the first frequency. The electronic circuit for maintaining the oscillations of resonator is a circuit with an amplifier-inverter (2), whose transconductance (gm) is determined so that the oscillations take place only according to the fundamental mode of vibrations in torsion. The resonator has also another mode of vibraton in flexion, which is the first overtone of flexion, at a third frequency which is higher than the frequency of fundamental mode of vibration in torsion. The electronic circuit comprises the amplifier-inverter (2) with input (A) and output (B) where capacitors (C1, C2) are connected, respectively, the quartz-crystal resonator (1) connected in the feedback path of amplifier-inverter, and a feedback resistor (RF) connected between the input and the output of amplifier-inverter. The amplifier-inverter (2) is of CMOS type, where the drains of two complementary transistors are connected in common forming the output (B), and the gates are connected in common forming the input (A). The feedback resistance (RF) is determined so to substantially reduce the maximum transconductance with respect to the fundamental mode of vibration in flexion. The resonator is in the form of a tuning fork laid out so that the frequency of fundamental mode of vibration in torsion is substantially equal to a multiple of 32.768 kHz. The oscillator device comprises a divider circuit connected at the output of electronic circuit allowing the derivation of a signal having the frequency of 32.768 kHz. The frequency of fundamental mode of vibration in torsion is substantially equal to 393.216 kHz, and the division is by 12. The resonator and the electronic circuit are mounted in the same casing.
Patent AT-E357020-T1 (AT)
Inventor: YAO LI-HO
IPC: G06F3/00
Filed: 1999-11-22
Granted: 2007-04-15
Abstract: A dual interface memory card and an adapter module for the memory card are disclosed to convenient transfer data between the memory card and a computer. The dual interface memory card has a memory unit and a micro control unit connected to the memory unit. The micro control unit includes a USB interface for connecting to a computer whereby the computer is able to read data from and write data to the memory unit, and a host interface for connecting to an electronic product which has the memory card installed therein such that data output from the electronic product can be stored in the memory unit. The adapter module is provided to conveniently connect the dual interface memory card to the computer. <IMAGE>
Patent AT-E214064-T1 (AT)
Inventor: PEGLION JEAN-LOUIS
IPC: C07D211/58
Filed: 1999-08-20
Granted: 2002-03-15
Abstract: A compound selected from those of formula (I): wherein: R1, R2, R3 and R4, which may be identical or different, represent hydrogen, halogen, alkyl, alkenyl, alkynyl, hydroxy, alkoxy, trihaloalkyl, or any pair may form a heterocycle, R5 represents hydrogen, alkyl, or arylalkyl, R6 represents hydrogen, halogen, alkyl, hydroxy, alkoxy, or trihaloalkyl, A, together with the carbons of the phenyl, represents a heterocycle, their isomers and addition pharmaceutically-acceptable acid or base salts thereof, and medicinal products containing the same which are useful in the treatment of pathologies in which 5HT1B receptors are involved.
Patent AT-E227410-T1 (AT)
Inventor: LECERF PHILIPPE
IPC: F24H1/26
Filed: 1999-02-02
Granted: 2002-11-15
Abstract: The invention concerns a heating unit for oil or gas boiler, wherein said heating unit (3) comprises a case (5) lined internally, in a rear zone, with a shell (6), ring-shaped transverse fins (35) are provided between the shell (6) and the case (5) for defining transverse annular channels (36) wherein the fuel gases follow in parallel a transverse path before emerging from the heating unit (3), thereby improving heat exchange between the fuel gases and the water (22) they are meant to heat.
Patent AT-E217074-T1 (AT)
Inventor: LAPWOOD GERALD
IPC: F41A21/30
Filed: 1999-01-22
Granted: 2002-05-15
Abstract: An gun-silencer (1) for mounting at the muzzle (9) of a gun-barrel comprises a baffle-free, generally-cylindrical gas-expansion chamber (2) intermediate a proximal entry-port (6) and a distal exit-port (7) both aligned with said gun-barrel when mounted thereon, the internal end walls of said expansion chamber being divergent from the entry-port at its proximal (3) end over a curve whose ends subtend an angle not greater than 90 DEG , and convergent on the exit-port (6) at its distal end (7) over a curve whose ends subtend an angle greater than 90 DEG .
Patent AT-E331739-T1 (AT)
Inventor: CHEN TAO
IPC: A61K9/127
Filed: 1999-04-27
Granted: 2006-07-15
Abstract: The present invention relates generally to the amphiphilic polyelectrolyte, poly(2-ethylacrylic acid) and covalently bonded lipids to generate Lipo-PEAA. These Lipo-PEAA are then used to make pH-sensitive liposomes which become unstable, permeable or fusogenic with certain pH changes. In addition, this invention generally describes methods for delivering therapeutic compounds and drugs to target cells by administering to a host the pH-sensitive liposomes of the present invention.
Patent AT-E473748-T1 (AT)
Inventor: SUGIHARA KATSUHIRO
IPC: A61K31/7105
Filed: 1999-05-24
Granted: 2010-07-15
Abstract: A process for producing a homogeneous nucleic-acid-containing composite preparation of good quality which is capable of sterilization by filtration and is characterized by containing no coarse particles having a size of 7  mu m or larger, which are regarded as unsafe for the human body. The process for producing the preparation, containing a composite of a cationic carrier with a nucleic acid polymer, is characterized in that two single-stranded nucleic acid polymers capable of at least partly forming a double-stranded state are separately added, each in the single-stranded state, to either a cationic carrier or a material from which the cationic carrier is to be formed, and all these ingredients are subjected to a dispersing treatment.
Patent AT-E227801-T1 (AT)
Inventor: FRASE HANS-JUERGEN
IPC: E05G1/024
Filed: 1999-05-21
Granted: 2002-11-15
Abstract: A method for assembling a strongbox and for subsequently coating an equipped and connected framework with coating elements and at least one door. The coating is in the form of a bottom element and frame elements at the front end and/or the rear end of the framework and lateral elements and an upper element. The coating accommodates the framework depending on the type of protection required. According to this invention, the elements are interlinked by simple joining elements. It is also possible to juxtapose several partial boxes to provide an aggregate box.
Patent AT-E282477-T1 (AT)
Inventor: WEIR JOHN DOUGLAS
IPC: B05D3/10
Filed: 1999-07-14
Granted: 2004-12-15
Abstract: A non-chrome process for the pretreatment of substrate surfaces to simultaneously clean them and improve their bonding strength for organic coatings such as adhesives, protective primers, sealants, paints, composites and similar materials conventionally bonded to such substrates, including non-chromated or chromated curable organic resin protective coatings applied directly to bare aluminum substrates. The invention involves the use of novel wipe solvent compositions containing a major volume of an environmentally-safe volatile organic solvent which has a low composite vapor pressure or is otherwise exempt from federal, state or local regulations, and a minor volume of a polyfunctional coupling agent, preferably of the silane type.
Patent AT-E297452-T1 (AT)
Inventor: BLEEKER IDO PIETER
IPC: C09J103/06
Filed: 1999-07-19
Granted: 2005-06-15
Abstract: The invention relates to an adhesive composition comprising a derivative of a starch, which comprises at least 95 wt. % of amylopectin, based on dry substance of the starch, wherein the derivative is obtainable by cross-linking, etherification, esterification or a combination thereof, of the starch. The invention further relates to a process for preparing the adhesive composition and to the use thereof for adhering wallpaper or billposter to a substrate.
Patent AT-E313034-T1 (AT)
Inventor: KATZ ODED
IPC: F16L19/08
Filed: 1999-08-18
Granted: 2005-12-15
Abstract: A pipe coupling includes a body member (10) formed with a bore (11) for receiving one end of a pipe (P) to be coupled; a sealing ring (20) and a compression sleeve (30) receivable within the bore (11); a radially-deformable gripping ring (40) having one end abuttable against the compression sleeve (30), a securing nut (50) threaded on the body member (10) and engageable with the gripping ring (40) to move the gripping ring (40) axially and to effect a sealing action via the compression sleeve (30) and the sealing ring (20), and also to compress the gripping ring (40) radially to effect a gripping action of the pipe (P) received in the bore (11); and an axially-extending limit element (45) between the gripping ring (40) and the body member (10) effective to cause the nut (50), when tightened; (a) in an initial stage, to move the gripping ring (40) and the compression sleeve (30) until the limit element engages (45) prevents further axial movement of the gripping ring (40); and (b) in a final stage, to radially deform the gripping ring (40) to produce the gripping action, and then to compress the sealing ring (20) against the internal annular shoulder (14) of the body member to produce the sealing action.
Patent AT-E269955-T1 (AT)
Inventor: MENZEL STANLEY WILLIAM OTTO
IPC: F16L57/00
Filed: 1999-09-22
Granted: 2004-07-15
Abstract: A machine (200) for winding a strip of material (212) into a helical pipe wherein adjacent convolutions of the strip (212) are interlocked. The machine comprises: a frame (220) having circumferentially spaced supports in the form of rollers (266, 276, 278, 286, 288, 296 and 298) adapted to bear against the inner periphery of the pipe being wound, the outer peripheral surfaces of the rollers forming a helical path for the strip (212) and along which the strip (212) is directed when the machine (200) is in use; driving rollers (224) mounted to the frame (220) for driving the strip (212) around the outside of the rollers so as to follow the helical path and cause the adjacent edges the strip (212) to interlock; and drive means (226) mounted to the frame for driving the driving rollers (224). The driving rollers (224) and the drive means are located wholly inside of the path formed by the rollers and no part of the machine (200) engages the outer periphery of the pipe being wound.
Patent AT-E277112-T1 (AT)
Inventor: ALBRECHT GERHARD
IPC: C08J3/12
Filed: 1999-09-23
Granted: 2004-10-15
Abstract: Stabilized, water-soluble polymer powders based on polyoxyalkylene glycol carboxylates are described, wherein the powders comprise from 0.01 to 10% by weight of a stabilizer selected from the group consisting of phenols, amines, phosphites, thioethers, and also thioacids, and where the stabilizer was added in liquid or dissolved form to the aqueous polymer solution prior to its conversion into the powder form. The polymer powders thus protected against autoignition and oxidative degradation have unexpectedly high thermooxidative stability, even on exposure to high temperatures and oxidizing action (air, oxygen).
Patent AT-E285176-T1 (AT)
Inventor: BATH COLIN
IPC: A01N43/40
Filed: 1999-10-18
Granted: 2005-01-15
Abstract: A method for the preservation of a plastics material against the growth of deteriogens which comprises treating the plastics material with a composition comprising a) an isothiazolin-3-one such as N-n-octyl- or 4,5-dichloro-N-n-octyl-isothiazolin-3-one and b) the metal complex of a thiohydroxamic acid such as 2:1 zinc complex of 3-hydroxy-4-methylthiazol-2(3H)-thione or the 2:1 zinc complex of 1-hydroxypyridine-2-thione.
Patent AT-E269351-T1 (AT)
Inventor: SCOZZARI ANTHONY
IPC: C07H21/00
Filed: 1999-10-01
Granted: 2004-07-15
Abstract: The present invention describes methods for linking phosphoramidite nucleosides to a solid support-bound nucleoside. This invention presents novel processes for synthesizing oligonucleotides. Acetonitrile having a water content between 30 ppm and about 1250 ppm is used as the solvent for the washing steps in solid phase oligonucleotide synthesis, or is used as a solvent for the capping reagent or oxidizing reagent. The processes of the present invention are amenable to large-scale, economic oligonucleotide synthesis using the phosphoramidite method.
Patent AT-E332365-T1 (AT)
Inventor: PELTZ STUART
IPC: G01N33/50
Filed: 1999-05-27
Granted: 2006-07-15
Abstract: This invention provides a method of modulating translation termination efficiency of mRNA and/or promoting degradation of abberant transcripts. Also, this invention provides a method of screening for a drug active involved in enhancing translation termination and a method for identifying a disease state involving defective the protein complex.This invention provides a purified complex comprising an amount of a human Upf1p protein, a peptidyl eucaryotic release factor 1 (eRF1) and a peptidyl eucaryotic release factor 3 (eRF3) effective to modulate translation termination. Further, this invention provides an expression vector which comprises a nucleic acid encoding a human Upf1p protein, a peptidyl eucaryotic release factor 1 (eRF1) and a peptidyl eucaryotic release factor 3 (eRF3) operably linked to a regulatory element.This invention provides an antibody which binds to the complex comprising an amount of a human Upf1p protein, a peptidyl eucaryotic release factor 1 (eRF1) and a peptidyl eucaryotic release factor 3 (eRF3) effective to modulate translation termination. This invention provides an agent which inhibits or modulates the binding of human Upf1p to eRF1 or eRF3 The agent may inhibit or facilitate the binding of human Upf1p to eRF1 or eRF3.
Patent AT-E225005-T1 (AT)
Inventor: SCHUBERT WERNER
IPC: F16C33/14
Filed: 1999-11-09
Granted: 2002-10-15
Abstract: The invention relates to a rolled-up plain bearing bush made from a metal/plastic composite plain bearing material whose wall has a thickness of at least 0.75 mm and which can be pressed into an opening of said bearing to form a medium-force fit. The inventive bearing bush also comprises a metal supporting layer and a sliding layer. In order to reduce weight and corrosion, the plain bearing bush is characterized in that the metal supporting layer is made of an aluminum alloy and the sliding layer consists of an expanded aluminum metal alloy section and a mixture of plastic sliding material that is applied to the expanded metal section and in the openings thereof in addition to optionally containing fillers that improve caloric conductibility and tribiological properties and the supporting layer is glued using an additional PFA-layer arranged therebetween.
Patent AT-E253397-T1 (AT)
Inventor: KOLMEDER MICHAEL
IPC: B01D46/00
Filed: 1999-11-18
Granted: 2003-11-15
Abstract: The invention relates to filter, especially for the intake air of an internal combustion engine which filter comprises reinforcements for the housing parts (10, 11). The reinforcement consists especially of a stay consisting of a hollow tube (21) and a threaded tube (22). Said tubes are stably linked with one another by means of a screw (23), thereby allowing a good bracing of the filter housing. The bracing of the filter housing effectively reduces the natural vibration of the housing while the overall weight of the filter remains substantially the same. Provision of such a stay is made possible by a recess (24) in the filter element (12). Said recess carries an additional seal (25) which seals the recess towards the tube. In this manner, the raw side (14) and the clean side (15) of the filter are reliably sealed from one another. In addition, the mounting of the additional seal between the hollow tube (21) and the threaded tube (22) can additionally stabilize the flat filter element.
Patent DE-06014263-T1 (DE)
Title: Spektraldarstellung von biologischen Proben
Inventor: LEVENSSON RICHARD M
IPC: G01J3/32
Filed: 2004-09-23
Abstract: Verfahren,
welches folgendes umfasst:  Bereitstellen von spektral aufgelöster Information über Licht,
das aus unterschiedlichen räumlichen
Lokalisierungen einer biologischen Probe in Antwort auf eine Beleuchtung
der Probe kommt, wobei das Licht Beiträge aus unterschiedlichen Komponenten
in der Probe einschließt;  Zerlegung
der spektral aufgelösten
Information für
jede von mindestens einigen der unterschiedlichen räumlichen
Lokalisierungen in einen Beitrag aus einer spektralen Schätzung eines
reinen Spektrums für
mindestens eine erste der Komponenten in der Probe; und  Konstruieren
eines Bilds der Probe, basierend auf der Zerlegung, um vorzugsweise
eine ausgewählte
der Komponenten zu zeigen,  wobei die Zerlegung das Herleiten
der Schätzung
des reinen Spektrums für
die erste Komponente basierend auf sowohl der spektral aufgelösten Information,
entsprechend einem ersten Satz von einer oder mehreren der unterschiedlichen
räumlichen
Lokalisierungen, als auch einer spektralen Schätzung eines reinen Spektrums
für eine zweite
der Komponenten umfasst.
Patent DE-07003891-T1 (DE)
Title: Vorrichtung und Verfahren zur Erzeugung von Tonhöhenwellensignalen und Vorrichtung sowie Verfahren zum Komprimieren, Erweitern und Synthetisieren von Sprachsignalen unter Verwendung dieser Tonhöhenwellensignale
Inventor: SATO YASUSHI
IPC: G10L25/90
Filed: 2002-08-30
Abstract: Sprachsynthesegerät, umfassend:  eine
Speichereinrichtung zum Speichern von Rhythmusinformation, die den
Rhythmus einer Sprachaufnahme einer Sprachlauteinheit darstellt,
von Tonhöheninformation,
die die Tonhöhe
der Sprachaufnahme darstellt, und von Spektrumsinformation, welche
die zeitliche Schwankung in der Grundfrequenzkomponente und der
harmonischen Wellenkomponente eines Tonhöhenwellensignals zeigt, welches durch
Vereinheitlichung der Zeitlängen
der Bereiche erzeugt wurde, die mit der Einheitstonhöhe eines
Sprachsignals äquivalent
sind, welches die Welle der Sprachaufnahme mit solchen Informationen
darstellt, die mit der Sprachaufnahme in Übereinstimmung gebracht wurden;  eine
Prädiktionseinrichtung
zum Eingeben von Textinformation, die einen Text darstellt, und
zum Erstellen von Prädiktionsinformation,
die das Ergebnis der Prädiktion
der Tonhöhe
und des Spektrums einer Sprachlauteinheit darstellt, welche den
Text basierend auf der Textinformation bildet;  eine Abrufeinrichtung
zum Identifizieren einer Sprachaufnahme mit einer Tonhöhe und einem
Spektrum, welche die höchste
Korrelation mit der Tonhöhe
und dem Spektrum der Sprachlauteinheit aufweisen, die den Text basierend auf
der Textinformation, der Spektrumsinformation und der...
Patent DE-19710427-T1 (DE)
Title: Durch einen niedrigen grad an methylveresterung und eine hohe intrinsische viskosität charakterisiertes pektin
Inventor: ROLIN CLAUS
IPC: C08B37/00
Filed: 2019-03-18
Abstract: Ein Citruspektin, gekennzeichnet durch:a) einen Grad an Methylveresterung von 30 oder weniger; undb) eine Grenzviskosität von 5 dl/g oder mehr.