baber/WOPTO huggingface dataset:
Patent AU-2020204111-A1 (AU)
Title: Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids
Inventor: ANSELL STEVEN M
IPC: C07C219/08
Filed: 2020-06-19
Abstract: H:\Interwoven\NRPortbl\DCC\VZS\20339199_I.DOCX-18/06/2020 
Abstract 
Compounds are provided having the following structure:() or a pharmaceutically 
acceptable salt, tautomer or stereoisomer thereof, wherein Ri, Rb,R2 a, R2B R2 a R3 R 3b 
R4 , R4 b,Ri R6, R 7' R 8', R, L L2, a,b,c,d and e are as defined herein. Use ofthe compounds 
as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, 
compositions comprising the compounds and methods for their use and preparation are also 
provided.  
R N R2  R 
R"b R2b R 3b R44 
R 4 N ~R 
20000 
--- Compound A 
-a- MC3 
-0- Comouwd 5 
-z15000 -4- Compound a 
10000 
d 
0.0 0,2 GA 0,6 0.8 1.0 12 
mRNA Dose (mg/kg) 
Figure 3
Patent AU-2020225482-A1 (AU)
Title: Devices and systems for moving a person on a support apparatus
Inventor: FOX SAMUEL T
IPC: A61G7/05
Filed: 2020-02-21
Abstract: Various implementations include a device for moving a person on a support apparatus. The device includes a base, an expandable volume, and a sheet. The base has a first side, a second side, and a support apparatus coupler for coupling the device to a support apparatus. The expandable volume is disposed on a surface of the base between the first side and the second side and is actuatable from a first position to a second position. The sheet has a first portion that is stationary with respect to the base and a second portion. The sheet extends from the first portion, over the second side, over the expandable volume, and over the first side. Actuation of the expandable volume from the first position to the second position increases a length of the sheet extending from the second side of the base to the first side of the base.
Patent AU-2020233660-A1 (AU)
Title: Disease resistance loci in onion
Inventor: BLACK LOWELL
IPC: C12Q1/68
Filed: 2020-09-15
Abstract: The present disclosure provides for unique onion plants with disease resistance and 
desirable bulb color and their progeny. Such plants may comprise an introgressed QTL 
associated with multiple disease resistance coupled with a desirable bulb color. In certain 
5 aspects, compositions, including distinct polymorphic molecular markers, and methods for 
producing, breeding, identifying, selecting, and the like of plants or germplasm with disease 
resistance and/or desirable bulb color are provided.
Patent AU-2020256938-A1 (AU)
Title: Biomimetic ice-inhibiting material and cryopreservation liquid containing same
Inventor: WANG JIANJUN
IPC: G01N13/00
Filed: 2020-03-02
Abstract: Provided is a biomimetic ice-inhibiting material. A library of structures of compound molecules is constructed, wherein the compound molecule comprises a hydrophilic group and an ice-philic group. Next, spreading performance of each compound molecule at an ice-water interface is evaluated by means of molecular dynamics simulation (MD simulation). Finally, a compound molecule having the desired ice affinity and water affinity is selected by means of screening. The present application proposes for the first time a mechanism of ice-philicity and hydrophilicity of an ice-inhibiting material, applies MD simulation for the molecular structure design of the ice-inhibiting material, evaluates the ice-philicity and the hydrophilicity of the designed ice-inhibiting material by means of MD simulation, predicts ice inhibition performance of the ice-inhibiting material, and optimizes the structure thereof. The biomimetic ice-inhibiting material designed and selected by the method greatly inhibits the growth of ice crystals. When added to a cryopreservation reagent, the biomimetic ice-inhibiting material achieves a good cryopreservation effect even without DMSO.
Patent AU-2020267213-A1 (AU)
Title: Electronic apparatus and operation method thereof
Inventor: KIM DA YOUNG
IPC: G06Q10/08
Filed: 2020-07-20
Abstract: July 2020 
ABSTRACT 
Provided is a method of recognizing an item as a removal target based on 
expiration date-related information of the item, acquiring information on an actual 
quantity of the removal target and a remaining quantity among the actual quantity, and 
5 updating information on stock based on the acquired information, and an electronic 
apparatus therefor.
Patent AU-2020278806-A1 (AU)
Title: Method and system for electrical nerve stimulation
Inventor: TSUKRAN ROI MOSHE
IPC: A61N1/372
Filed: 2020-05-18
Abstract: Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subject's hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.
Patent AU-2020279752-A1 (AU)
Title: Systems and methods for evaluating tumor fraction
Inventor: FENDLER BERNARD
IPC: C12Q1/6886
Filed: 2020-05-20
Abstract: Disclosed herein are, at least in part, methods of determining a tumor fraction of a sample from a subject. The methods can include, for example, acquiring a value for a target variable associated with a subgenomic interval in the sample; determining, from the target variable, a certainty metric; accessing a determined relationship between a stored certainty metric and a stored tumor fraction; and determining, with reference to the certainty metric and the determined relationship, the tumor fraction of the sample.
Patent AU-2020285364-A1 (AU)
Title: System and method for monitoring wellbeing
Inventor: PARFITT DAVID THOMAS
IPC: G16H20/30
Filed: 2020-05-26
Abstract: A wellbeing monitoring system (21) for monitoring the wellbeing profile of a user (25), to provide real-time individualised risk-reduction feedback. The feedback is adapted to thereby motivate the user (25) to initiate action to improve his/her wellbeing. A user's insurance policy parameter (30) is correspondingly adjusted in real-time based on any monitored variation of the user's wellbeing. The system uses a plurality of wellbeing data input devices (22) and a processor (23) to process the received data (26) correlate this with predetermined data (28), to produce remediation data (29) and calculate a modified insurance policy parameter (32) to thereby produce an adjusted insurance policy parameter (31).
Patent AU-2020301632-A1 (AU)
Title: System and method for automated detection of clinical outcome measures
Inventor: ARMITAGE OLIVER
IPC: G16H50/20
Filed: 2020-06-26
Abstract: Systems, apparatus, and method(s) are provided for automatically detecting and/or estimating one or more clinical biomarker(s) of a subject. Sensor data is received from one or more sensor(s) associated with the subject. The sensor data is processed using a first set of machine learning (ML) model(s) configured to extract portions of sensor data relevant for estimating one or more clinical biomarker(s) of the subject. The extracted portions of sensor data from sensors associated with the subject are processed to determine one or more clinical biomarkers. The processing of the received extracted portions of sensor data includes using a second set of ML model(s) configured to estimate the one or more clinical biomarker(s) of the subject. The portions of sensor data may comprise the first set of ML model(s) being configured to extract segments of sensor data and classify the segments of sensor data based on one or more clinical biomarker components for use in the estimation of one or more clinical biomarkers of interest. The second set of ML model(s) are configured to estimate the one or more clinical biomarker(s) of the subject based on the extracted and classified segments of sensor data.
Patent AU-2020315554-A1 (AU)
Title: Surgical registration tools, systems, and methods of use in computer-assisted surgery
Inventor: KAYAL JORDAN
IPC: A61B34/20
Filed: 2020-07-09
Abstract: A surgical registration tool including a bone engagement structure comprising a distal condyle abutment structure, at least one posterior condyle abutment structure, a side condyle abutment structure, and an anterior shaft abutment structure. The distal condyle abutment structure includes a distal planar surface. The at least one posterior condyle abutment structure includes at least one planar surface extending distally from the distal planar surface and positioned perpendicular to the distal planar surface. The side condyle abutment structure includes a planar surface extending distally from the distal planar surface and positioned perpendicular to the distal planar surface and the at least one planar surface. The anterior shaft abutment structure extends distally from the distal planar surface and terminates at a distal tip. The registration tool also includes a handle coupled to the engagement structure and extending proximally therefrom, and a tracker array configured to couple to the handle.
Patent AU-2020319732-A1 (AU)
Title: MHC class II molecules and methods of use thereof
Inventor: HIRANO NAOTO
IPC: A61P31/00
Filed: 2020-07-29
Abstract: The present disclosure is directed to HLA class II molecules having a higher affinity for CD4 than naturally occurring HLA class II molecules. In certain aspects, the HLA class II molecule comprises a DR beta chain having (i) an amino acid other than leucine at a position corresponding to amino acid residue 114 of SEQ ID NO: 1, (ii) an amino acid other than valine at a position corresponding to amino acid residue 143 of SEQ ID NO: 1, (iii) or both (i) and (ii). Certain aspects of the present disclosure are directed to nucleic acid molecules encoding the HLA class II molecules, vectors comprising the nucleic acid molecule, cells comprising the same, and methods of use thereof.
Patent AU-2020334602-A1 (AU)
Title: Lithium ion battery for power tools
Inventor: SUBRAMANIAN ADITYA
IPC: H01M4/13
Filed: 2020-05-27
Abstract: There is provided a lithium ion battery for use in a power tool. The lithium ion battery includes a carbon-based negative electrode containing a certain weight content of silicon-based material, a positive electrode including a lithium metal oxide containing nickel, and a non-flammable electrolyte placed between the negative electrode and the positive electrode. The weight content of silicon-based material in the negative electrode is no less than 5%. A composition of nickel of the lithium metal oxide is no less than the composition of other metals of the lithium metal oxide.
Patent AU-2020368425-A1 (AU)
Title: A mounting structure for a vibration sensing system
Inventor: RICHARDS LES
IPC: G01D5/353
Filed: 2020-10-19
Abstract: Described herein is an optical fibre mounting structure (180) for fibre vibration sensing of a distributed system (100) of spaced apart vibration sources (112-131). Mounting structure (180) includes a base portion (200) having a two dimensional surface area defining a vibration surface (202). A mounting apparatus (236) is adapted to mount the base portion (200) to a support structure (e.g. 104) of the distributed system (100) adjacent one of the vibration sources. A fibre engagement structure (e.g. 210-215) is provided for supportively engaging a length (218) of optical fibre in contact with the vibration surface (202).
Patent AU-2020378976-A1 (AU)
Title: Roach gel formulations
Inventor: MARWAH PANKAJ
IPC: A01P7/04
Filed: 2020-10-20
Abstract: An insecticidal gel formulation including an insecticide active agent, sugar, sorbitol, hydrophilic fumed silica, xanthan gum, and a solvent is disclosed. Further, the insecticidal gel formulation comprises a total amount of hydrophilic fumed silica and xanthan gum of at least 3.6% by weight of the total insecticidal gel formulation.
Patent AU-2020391167-A1 (AU)
Title: Methods, devices, and systems for adjusting laboratory HbA1c values
Inventor: XU YONGJIN
IPC: G16H20/17
Filed: 2020-11-24
Abstract: Physiological parameters that related to the kinetics of red blood cell hemoglobin glycation, red blood cell elimination, and red blood cell generation within the body of a subject can be used, for example, to calculate a more reliable calculated HbA1c (cHbA1c), adjusted HbA1c (aHbA1c), and/or a personalized target glucose range, among other things, for subject-personalized diagnoses, treatments, and/or monitoring protocols. Such physiological parameters may be determined using a model that considers cross-membrane glucose transport and glycation.
Patent AU-2020397170-A1 (AU)
Title: Formulations of anti-CD38 antibodies for subcutaneous administration
Inventor: BALLET THOMAS
IPC: A61K39/395
Filed: 2020-12-04
Abstract: Provided are formulations of anti-CD38 antibodies suitable for subcutaneous administration to a subject in need thereof. The formulations include a high concentration of antibody, a viscosity lowering agent, a stabilizing agent, a buffering agent and a surfactant. In certain embodiments, the viscosity of the solution is at most 25 mPa·s, and the pH of the solution is 5.9 to 7.0. In certain embodiments, the anti-CD38 antibody is isatuximab. The formulations will find use in treating CD38
Patent AU-2020408055-A1 (AU)
Title: Synchronization of lighting networks for agriculture production
Inventor: SUNTYCH JON DAREN
IPC: G06Q50/02
Filed: 2020-12-18
Abstract: Embodiments of the present disclosure provide systems, apparatuses and methods for synchronous communication and control of LED lights and sensors in an LED light array containing two or more LED lights. Through the use of a master clock within a gateway and/or a master controller that is in communication with LED lights in an array that is in a facility, such as in a greenhouse, hot house, poultry egg production facility, a hospital, dairy production or other lighting facilities, the gateway and/or master controller is capable of synchronizing the emission of light or photons from an LED light array by generating a master signal that contains commands and time from a master clock within the signal that is transmitted to each of the LED lights within an array.
Patent AU-2020414266-A1 (AU)
Title: Core model augmented reality
Inventor: LOPEZ OLIVIER
IPC: G01N21/01
Filed: 2020-12-21
Abstract: A method of registering geological data at a formation core tracking system, the method comprising: at the tracking system, registering a formation core provided within a field of view of an optical imaging system of the tracking system; tracking the orientation of the formation core relative to the tracking system and the distance of the formation core relative to the tracking system; obtaining data associated with a first section of the formation core which is located at a predetermined distance from the tracking system, displaying the data together with an image of the formation core such that an augmented reality image is provided on a display device of the tracking system, changing the distance between the tracking system and the core; and updating the displayed data by obtaining data associated with a second section of the formation core which is located at said predetermined distance from the tracking system.
Patent WO-2021248205-A1 (WO)
Inventor: JAMES ALLAN MARTIN
IPC: B25B11/02
Filed: 2021-06-11
Abstract: Disclosed herein is an apparatus for facilitating assembly and/or dis-assembly of a vehicle brake assembly, the apparatus being configured to be positionable relative to the brake assembly and movable away from the vehicle and further being configurable to support and hold a selected part of the vehicle brake assembly for facilitating removal and installation thereof, and wherein the apparatus comprises a positioning assembly configured to controllably move the selected held part of the brake assembly relative to a base of the apparatus, and the positioning assembly is further configured to raise and lower the held selected part between a lowered position where the selected part is in contact with or on the ground and a raised position where the selected part and adaptor assembly is transportable by the apparatus to or from the vehicle.
Patent AU-2021230540-A1 (AU)
Title: Methods and compositions for treating cannabis use disorder and mitigating cannabinoid withdrawal
Inventor: CONSTANTINE GINGER D
IPC: A61P25/30
Filed: 2021-03-04
Abstract: The present invention provides methods of treating cannabis withdrawal syndrome and other cannabis related conditions, including cannabis use disorder, in a subject, comprising administering to the subject in need thereof an effective amount of a cannabinoid or an effective amount of a cannabinoid and an effective amount of a second active agent, such as gabapentin or a gabapentin analog.
Patent AU-2021236465-A1 (AU)
Title: Biomarker for use in treating anemia
Inventor: SUNG VICTORIA
IPC: G01N33/53
Filed: 2021-09-21
Abstract: : 
Provided herein are methods of treating diseases associated with anemia or ineffective 
erythropoiesis by using the level and/or activity of a ligand of an activin receptor, in particular, 
Growth differentiation factor II (GDF 1l), as an indicator of responsiveness of a patient to the 
treatment, efficacy of the treatment, or appropriate dosage for the treatment with an activin type 11 
receptor inhibitor.
Patent AU-2021239795-A1 (AU)
Title: Full duplex operation of a portable communications device in a time division multiple access radio system
Inventor: V K CHACKO V C PRAKASH
IPC: H04W52/02
Filed: 2021-02-19
Abstract: Portable communications device (110) and method (500) for full duplex operation in a time division multiple access radio system. The method (500) includes providing a switch (340) for connecting one of a first voltage controlled oscillator (330A) and a second voltage controlled oscillator (330B) to a synthesizer (350). The synthesizer (350) generates a first frequency when connected to the first voltage controlled oscillator (330A) and generates a second frequency when connected to the second voltage controlled oscillator (330B). The method (500) also includes controlling, using an electronic processor (310) coupled to the switch (340), the switch (340) to connect the first voltage controlled oscillator (330A) to the synthesizer (350) for a first timeslot (220A), and controlling, using the electronic processor (310), the switch (340) to disconnect the first voltage controlled oscillator (330A) from the synthesizer (350) and connect the second voltage controlled oscillator (330B) to the synthesizer (350) for a second timeslot (220B). The second timeslot (220B) is immediately adjacent to the first timeslot (220A).
Patent AU-2021240046-A1 (AU)
Title: MDM2 degraders and uses thereof
Inventor: JI NAN
IPC: A61K31/4015
Filed: 2021-03-19
Abstract: The present invention relates to compounds and methods useful for the modulation of mouse double minute 2 homolog ("MDM2") protein via ubiquitination and/or degradation by compounds according to the present invention.
Patent AU-2021240187-A1 (AU)
Title: System and method for third party application activity data collection
Inventor: ABRAHAMI YOAV
IPC: G06F17/22
Filed: 2021-09-29
Abstract: SYSTEM AND METHOD FOR THIRD PARTY APPLICATION 
ACTIVITY DATA COLLECTION 
ABSTRACT 
A system includes at least one hub to coordinate at least one activity message between a 
website and at least one third party application where the at least one activity message has a 
standardized format, and an activity coordinator to listen to the at least one activity message 
and at least to add data extracted from the at least one message to a stream associated with at 
least one of an identified contact and an anonymous contact and where the at least one of an 
identified contact and an anonymous contact is a user of the website. The system also 
includes a contacts coordinator to retrieve and analyze contact related information from the 
stream and to enrich previously held information for the contact and at least one database to 
store the activity streams and the contact related information for use by the website and by 
the contact.
Patent AU-2021259608-A1 (AU)
Title: Teledermatology system and methods
Inventor: DOBAK III JOHN DANIEL
IPC: A61B10/02
Filed: 2021-04-21
Abstract: Provided herein are systems, platforms, and methods for conducting remote dermatology evaluation and sampling. A variety of skin conditions can be evaluated and tested effectively using the telehealth solution disclosed herein, including but not limited to melanoma, non-melanoma skin cancer, inflammatory skin conditions, and the like. In one example, non-invasive melanoma skin cancer detection is possible with a pigmented lesion assay (PLA) genomic test that accurately assesses a variety of skin lesions, such as suspicious moles.
Patent AU-2021260154-A1 (AU)
Title: Generation of microservices from a monolithic application based on runtime traces
Inventor: XIAO JIN
IPC: G06F11/30
Filed: 2021-03-24
Abstract: Systems, computer-implemented methods, and computer program products to facilitate generation of microservices from a monolithic application based on runtime traces are provided. According to an embodiment, a system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise a model component that learns cluster assignments of classes in a monolithic application based on runtime traces of executed test cases. The computer executable components can further comprise a cluster component that employs the model component to generate clusters of the classes based on the cluster assignments to identify one or more microservices of the monolithic application.
Patent AU-2021282448-A1 (AU)
Title: Methods for treating Alzheimer's disease
Inventor: FERRERO JAMES L
IPC: A61K39/00
Filed: 2021-12-08
Abstract: METHOD FOR TREATING ALZHEIMER'S DISEASE 
ABSTRACT 
A method for treatment of a human patient for Alzheimer's disease (AD) comprises sequentially 
administering multiple doses of a recombinant, fully human, anti-amyloid beta monoclonal 
antibody to the patient. In preferred embodiments, the antibody is administered in increasing 
amounts over a period of time. In preferred embodiments, the susceptibility of the patient to 
amyloid related imaging abnormalities (ARIA) is thereby reduced.
Patent AU-2021282650-A1 (AU)
Title: Gravity force absorber for use in certain parachute and other systems
Inventor: ANTONIO ISHMAEL L
IPC: B64D17/36
Filed: 2021-06-04
Abstract: A shock absorber assembly, particularly for attenuating shocks transmitted to a person's body, especially to reduce shock to a paratrooper's body during a tethered cargo tandem jump. Specialized elastic absorber units are disposed between two connectors, such as carabiners, with a connector secured to a respective end of each absorber unit. Each absorber unit has a rupture length corresponding to its length when it is stretched to its maximum immediately before rupturing under tensile loading. A limiter strap also is secured between the connectors, with a connector on each end of the limiter strap. The limiter strap prevents the absorber units from breaking by preventing their stretch to their breaking point. A flap or bands are provided for temporarily maintaining the limiter strap folded in a compact bale until needed. In use, the complete shock absorber assembly is deployed between a cargo tether and a cargo harness.