baber/WOPTO huggingface dataset:
Patent PT-1811303-E (PT)
Title: Compounds for treating irritable bowel syndrome.
Inventor: LIN HENRY C
IPC: C12Q1/00
Filed: 2000-08-11
Abstract: Disclosed is a method of diagnosing imitable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, or Crohn's disease, which involves detecting the presence of small intestinal bacterial overgrowth (SIBO) in a human subject having at least one symptom associated with a suspected diagnosis of any of those diagnostic categories. Also disclosed is a method of treating these disorders, and other disorders caused by SIBO, that involves at least partially eradicating a SIBO condition in the human subject. The method includes administration of anti-microbial or probiotic agents, or normalizing intestinal motility by employing a prokinetic agent. The method improves symptoms, including hyperalgesia related to SIBO and disorders caused by SIBO. Also disclosed is a kit for the diagnosis or treatment of irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, or Crohn's disease.
Patent PT-2004034-E (PT)
Title: Device for facilitating the medical examination of an orifice
Inventor: BAKHTYARI-NEJAD-ESFAHANI ARASH
IPC: A61B1/233
Filed: 2007-03-29
Abstract: A device for facilitating the examination of an orifice includes a mount for a light source for illuminating the orifice, a connector for detachably mounting a dilator for insertion into and dilation of an orifice, and an actuator for operating a mounted dilator. The mounted dilator includes operative parts able to move apart from one another.
Patent PT-2137301-E (PT)
Title: Adenovirus with mutations in the endoplasmic reticulum retention domain of the e3-19k protein and their use in cancer treatment.
Inventor: PIQUERAS MANEL MARIA CASCALLO
IPC: A61K35/13
Filed: 2008-03-12
Abstract: The present invention relates to an adenovirus wherein said adenovirus replicates and it contains a mutation in the endoplasmic reticulum retention domain of E3-19K, and to the use of said mutant in treating cancer. Said mutant virus may also contain other mutations and insertions of DNA sequences used to confer selectivity and antitumor potency. The invention has application in the field of cancer therapy.
Patent PT-2152667-E (PT)
Title: Methods for the preparation of n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives
Inventor: ZINSER HARTMUT BURGHARD
IPC: C07C303/38
Filed: 2008-04-25
Abstract: A process for the preparation of N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives in which a (1-benzyl-2-hydroxy-3-isobutylamino-propyl)-carbamic acid derivative is reacted with a p-nitrophenylsulfonyl halide to provide the desired product in a high yield and degree of purity.
Patent PT-693065-E (PT)
Inventor: WOOD MICHAEL L
IPC: C07H21/00
Filed: 1994-03-23
Abstract: Novel coumarin derivatives comprising a coumarin moiety linked to a non-nucleosidic backbone moiety are disclosed. The resulting molecules are typically used as photoactivate cross-linking groups when incorporated into polynucleotides as replacements for one or more of the complementary nucleoside bases present in probes used in procedures involving nucleic acid hybridization reactions.
Patent PT-680963-E (PT)
Inventor: BJORGE SUSAN M
IPC: C07D207/34
Filed: 1995-05-03
Abstract: ((Hydroxyphenylamino)carbonyl)pyrrole derivs of formula (I) (lactone) and (II) (acid), and their salts and solvates, are new. R1= H or hydroxy protecting gp.
Patent PT-728748-E (PT)
Inventor: SENO KAORU
IPC: C07D403/12
Filed: 1994-12-19
Abstract: A benzodiazepine derivative of the formula (I): <CHEM> wherein R1 is a bond, -CH2-, -CH2O-, -OCH2-, -SCH2- or a group of the formula: <CHEM> R2 is a lower alkyl, -COOR5, -CONH(CH2)nCOOR5, -CONHSO2R5, -SO2NHCOR5, or an optionally substituted heterocyclic group (R5 is a hydrogen atom, lower alkyl or benzyl and n is an integer of 1 to 5); R3 is a bond, -CO- or -CONH-; and R4 is an optionally substituted heterocyclic group, optionally substituted lower alkyl, optionally substituted lower cycloalkyl, optionally substituted aryl, or lower alkoxycarbonyl group, or a pharmaceutically acceptable salt thereof, which has a high affinity for gastrin receptors and/or CCK-B receptors but not for CCK-A receptors, and is useful for treating diseases associated with gastrin receptors and/or CCK-B receptors without inducing the side effects associated with CCK-A receptors.
Patent PT-778447-E (PT)
Inventor: STUHLER HELMUT
IPC: F23C9/00
Filed: 1996-08-21
Abstract: The flame tube (21) of the burner (22) extends through the boiler door (23). The combustion chamber (24) of the boiler (25) is limited by a heat exchanger (26) with its outer walls (27) and by the rear wall of the boiler (28). The heat exchanger houses the heat exchange pipes (29) through which water to be heated flows. The water inlet (30) and outlet (31) are connected at the side. The insert (1) is centrally arranged in the combustion chamber so that the centreline of the flame coincides with its centreline, and is positioned on a locator comprising three bearing pins. The flame (34) starts shortly behind the flame tube and burns in the flow direction. Between the flame tube and the insert is a space (35) acting as a suction area (36). A part of the gas is recirculated via the suction area through the inlet aperture and through the injection openings (6) in the insert.
Patent PT-824417-E (PT)
Inventor: WEIJERS JOHANNES THEODORUS STE
IPC: B60R16/02
Filed: 1996-04-17
Abstract: There is described a battery clamp (1), comprising: a fastening clamp member (10) designed for attachment to a terminal of a battery; means (33) for receiving a cable (30); and a guard circuit (100) coupled between the fastening clamp member (10) and the receiving means (33). The guard circuit (100) comprises: a controllable switch (110), of which a current input (111) is electroconductively connected to the fastening clamp member (10), and of which a current output (112) is electroconductively connected to the receiving means (33); a control unit (130), of which a control output (133) is coupled to a control input (113) of the switch (110); and monitoring members (141-143) connected to monitoring inputs (134-136) of the control unit (130). The control unit (130) is adapted to control the switch (110) in response to signals received at its monitoring inputs (134-136).
Patent PT-873183-E (PT)
Inventor: SYMES KENNETH CHARLES
IPC: C11D17/08
Filed: 1996-12-23
Abstract: A liquid detergent concentrate has an outer liquid detergent phase and enzyme containing particles dispersed in the liquid phase. The particles have a polymer shell formed from a condensation polymer which is permeable to water and low molecular weight components of the outer liquid phase and the core comprises the enzyme, an inner liquid detergent phase in substantially equilibrium with the outer phase and a core polymer which causes stretching as a result of osmosis when the concentrate is diluted in water. Encapsulated precipitated enzymes are also disclosed.
Patent PT-1028750-E (PT)
Inventor: FRANCOIS ARMINJON
IPC: A61K39/295
Filed: 1997-09-15
Abstract: A multi-component vaccine composition is described comprising a cellular pertussis vaccine components (PT and FHA), diphtheria toxoid (DT), tetanus toxoid (TT), a conjuagate of a capsular polysaccharide of Haemophilus influenze type b and tetanus toxoid or diphtheria toxoid (Hib), Hepatitis B Surface Ag (HBsAg) and inactivated poliovirus (IPV). The composition may comprise the above compounds in a single solution, or certain components may be reconstituted from a lyophilized state by the other components of the vaccine. The administration of the multiple component vaccine resulted in no diminution in the immunogenicity of any component as a result of interference by other components of the vaccine.
Patent PT-954565-E (PT)
Title: Adipogenic differentiation of human mesenchymal stem cells
Inventor: PITTENGER MARK F
IPC: A61K35/12
Filed: 1997-07-21
Abstract: This invention relates to a composition which comprises mesenchymal stem cells which have been isolated from a human and which have potential to differentiate into cells of more than one connective tissue type and a substance in an amount effective to induce said stem cells to differentiate into the adipogenic lineage, wherein the substance which induces cells from the mesenchymal stem cell population to differentiate into the adipogenic lineage comprises a glucocorticoid and a compound which elevates intracellular levels of cAMP or which inhibits degradation of cAMP.
Patent PT-1000029-E (PT)
Inventor: HEYKANTS JOZEF JAN PIETER
IPC: C07D211/58
Filed: 1998-07-07
Abstract: The present invention concerns (+)-norcisapride, and its pharmaceutically acceptable acid additions salts, a process for preparing said compound, and its use for the manufacture of a medicament for treating gastro-intestinal disorders while avoiding central nervous system effects. Also provided are method of treating gastro-intestinal disorders.
Patent PT-1035941-E (PT)
Inventor: KARLSSON ROLF
IPC: B23K9/067
Filed: 1998-09-10
Abstract: The invention relates to an arrangement for contact arc ignition in manual TIG welding and to a method for welding with this arrangement. The arc is established by lifting the welding torch (12) after contact between electrode (13) and workpiece (14) under low ignition current. When the arc length is sufficient, the welder orders a change-over to welding current via an operating device (11). The invention can also be used for controlling the supply of heat to the workpiece both during continuous bead application and during the crater filling time at the end of welding. The invention creates reliable ignitions without extensive use of control electronics, and it substantially reduces the electrode wear in manual TIG welding.
Patent PT-1025645-E (PT)
Inventor: PARKER JAMES
IPC: H03L7/093
Filed: 1998-10-20
Abstract: A phase-locked loop circuit is disclosed which exhibits a wide capture range and a low quality factor (Q) to prevent ringing and improve stability without adding area, increasing power consumption or increasing noise levels. The phase-locked loop includes a comparator to generate an error signal, an oscillator which generates an output signal in response to a control signal and a loop filter which generates the control signal based on the error signal. The loop filter includes a first integrator operatively coupled through a threshold limit detector to a second integrator. The threshold limit detector supplies an electric charge to the second integrator only when the first integrator is proximate to either an upper limit or a lower limit of the first integrator's operating range. The oscillator generates the output signal which tracks the input reference signal frequency as an integer multiple of the input reference signal frequency. The oscillator generates the output signal in response to varying current levels of the control signal. The loop filter further includes a pump-up and a pump-down charge pump that act in tandem under activation by the threshold limit detector. The loop filter includes a duty cycle limiter switch that limits the supply of the charge to the second integrator to a predetermined time period.
Patent PT-1002936-E (PT)
Inventor: KALLINA GUENTER
IPC: F01K7/38
Filed: 1999-11-16
Abstract: A condensate warm-up device in a feed-water vessel (2) of a power station operates by means of steam removal (22) from a turbine (10,11) with a steam line (31) leading into the lower condensate space (30) of the feed-water vessel (2) and in whose flow is arranged a controlled adjustment device (25). The adjustment or setting device (25) has a controlled steam branch line (33) which discharges into the steam space (32) over the condensate space (30) of the feed-water vessel (2).  The adjustment or setting device (25) is specifically a three-way valve. With a feed-water vessel (2) arranged with a degasifier (34), the controlled steam-branch line (40) is arranged into the steam space (32) up-stream of a further steam-branch line (41) into the degasifier (34).
Patent IE-890036-L (IE)
Title: Medical treatment
IPC: A61K31/7076
Filed: 1989-01-06
Abstract: A reverse transcriptase inhibitor such as 3 min - azido - 3 min  - deoxythymidine is used for the treatment or prophylaxis of a retrovivus-associated carcinoma such as breast cancer in a human.
Patent IE-31931-L (IE)
Title: Edible meat coatings.
IPC: A23L13/00
Filed: 1968-01-25
Abstract: 1,201,650. Meat coating composition. W. R. GRACE & CO. 28 Dec., 1967 [25 Jan., 1967], No. 58805/67. Heading A2B. A meat coating composition comprises a water in oil emulsion comprising 6-98 parts by weight of fat, 2-74 parts water, 0.1-22% by weight of said fat consisting of an emulsifying system containing 1-12 parts of an edible non-ionic hydrophilic and lipophilic emulsifier having a hydrophilic and lipophilic balance, as defined, of 3-6, the hydrophilic emulsifier comprising 0-75% wt. of the system, and the lipophilic emulsifier comprising 100-25% wt. of the system, and having an iodine value of at least 8, and from 0 to 10 parts by weight of an edible wax, said emulsion containing 0.3-2.0 parts by weight of an edible thermal gelling water soluble gum, for example methyl cellulose, per 100 parts of said emulsion. The composition may also contain up to 77 parts by weight of seasoning ingredients, such as salt, dehydrated onion, pepper, nutmeg, protein hydrolysates and autolysates, sugar, tomato puree, and apple juice. Preservatives such as sorbic and benzoic acids and their salts may also be present.
[GB1201650A]
Patent IE-860242-L (IE)
Title: Transferring electrical energy to and from living tissue
IPC: A61B5/332
Filed: 1986-01-28
Abstract: Apparatus for transferring electrical energy to and from living tissue comprises a glove of thin, flexible elastomeric material, which carries electrodes, electrically connected to a connector disposed at the cuff of the glove. The connector permits the electrodes to be electrically connected to a source of electrical energy or to a load, so that electrical energy may be applied to or drawn from living tissue.
[US4765343A]
Patent IE-870298-L (IE)
Title: Two part mailer with return envelope
IPC: B42D15/08
Filed: 1987-02-04
Abstract: The business or other institution is provided with two complementary series of blank form parts. One of these contains one or more elements of a form of construction (multiple ply, window, glassine-patched window, glue spots, patches or strips) which would make it incompatable for use with today's commercially predominate non-impact printers. The other contains none of such elements and is suited for being run through a business computer-controlled non-impact printer for the purpose of printing of variable information thereon, and of being thereafter assembled and united increment for increment with form parts from the first series, using presently available assembling and uniting apparatus, whereupon the united forms may be successively severed into thus individualized communications and dispatched to their respective addressees.
Patent IE-38918-L (IE)
Title: Colouring a vegetable protein product
IPC: A23L1/275
Filed: 1974-02-22
Abstract: 1464376 Colouring extruded vegetable protein UNILEVER Ltd 22 Feb 1974 [26 Feb 1973] 9235/73 Heading A2B A brown colour is imparted to textured extruded vegetable protein by adding a C 5 sugar or a phosphate ester of a C 5 sugar to the proteinaceous dough or mixture before it is fed to the extruder. The sugar or ester is not more than 10% of the protein present. Further colourings may also be incorporated to simulate the colours of different meats, in an amount of not more than 60% of the sugar or ester. An amino acid, e.g. lycine, arginine, histidine, may also be incorporated in an amount of 1/10 to 10 times the amount of sugar or ester. The dough may be made from defatted soya meal with a protein content of 50 to 60%.
[GB1464376A]
Patent IE-850398-L (IE)
Title: Aryl and heterocyclyl compounds
IPC: C07C255/49
Filed: 1985-02-18
Abstract: A compound of the formulawherein X has the formulawherein ring A is phenyl, naphthyl or heterocyclic; wherein R' is hydrogen, alkyl, alkanoyl or aroyl; wherein R<sup>2</sup>, R<sup>3</sup> and R<sup>4</sup>, which may be the same or different, each is an electron withdrawing substituent selected from halogeno, nitro, cyano, trifluoromethyl, alkylthio, alkylsulphinyl and alkylsulphonyl or each is hydrogen, alkyl, alkoxy or dialkylamino provided that when ring A is phenyl or naphthyl at least one of R<sup>2</sup>, R<sup>3</sup> and R<sup>4</sup> is an electron-withdrawing substituent; wherein R<sup>5</sup> and R<sup>6</sup>, which may be the same or different, each is hydrogen, halogeno or alkyl; wherein R<sup>7</sup> is alkyl or halogenoalkyl; and wherein R<sup>S</sup> is carbamoyl, alkyl, cycloalkyl, alkenyl, alkynyl, halogenoalkyl, halogenoalkenyl, halogenoalkynyl, alkanoyl, alkylcarbamoyl, dialkylcarbamoyl or aroyl; or wherein R<sup>8</sup> is alkyl or alkenyl which bears one or more substituents selected from cyano, carbamoyl, amino, hydroxy, alkanoyl, alkoxy, alkylthio, alkenylthio, alkylsulphinyl, alkenylsulphinyl, alkylsulphonyl, alkenylsulphonyl, alkanoylamino, alkoxycarbonylamino, alkylsulphonamido, alkylamino, dialkylamino dialkylsulphamoyl, aroyl, aryl, arylthio, arylsulphinyl, arylsulphonyl, heterocyclylthio, heterocyclylsulphinyl and heterocyclylsulphonyl; or wherein R<sup>8</sup> has the formulawherein ring B is phenyl, naphthyl or heterocyclyl and wherein R<sup>2</sup>, R<sup>3</sup> and R<sup>4</sup> have any of the meanings stated above, provided that when R<sup>7</sup> is methyl R<sup>8</sup> is not also methyl.
Patent IE-44625-L (IE)
Title: Security closure
IPC: B65D41/58
Filed: 1977-02-25
Abstract: A security closure for a container, comprises a capsule, and a stopper including a tearstrip having a free end which in use passes through an opening in the capsule, the opening having a width greater than its height. The capsule has two lines of weakness which are aligned with the longitudinal edges of the tearstrip.
[US4084719A]
Patent IE-40728-L (IE)
Title: Methanodibenzocycloheptapyrroles.
IPC: C07D209/70
Filed: 1975-03-04
Abstract: To prepare compounds of the formula (I) <IMAGE> having the radicals R<1>, R<2> and R defined in Patent Claim 1, compounds of the formula (XII) <IMAGE> are reacted with a reducing agent. The compounds obtained exhibit activities of pharmacological interest in the trans-structures. They can be employed as tranquillisers and analgesics.
[GB1470900A]
Patent IE-44738-L (IE)
Title: Reduction of cephalosporin sulphoxides to cephalosporins.
IPC: C07D501/32
Filed: 1977-04-15
Abstract: Cephalosporin sulfoxides are reduced to the corresponding cephalosporin with acyl bromides, e.g., acetyl bromide, in the presence of a bromine scavenger, e.g., an olefin, acetylene, phenol, phenol ether, or an organophosphite. For example, p-nitrobenzyl 7-phenoxyacetamido-3-methyl-3-cephem-4-carboxylate sulfoxide is reduced with acetyl bromide in the presence of amylene to p-nitrobenzyl 7-phenoxyacetamido-3-methyl-3-cephem-4-carboxylate.
[US4044002A]
Patent IE-35533-L (IE)
Title: Organic phosphorus compounds and intermediate¹oxazolopyridines
IPC: C07F9/653
Filed: 1971-06-25
Abstract: New sulphur containing phosphorus compounds of pyrido-oxazole derivatives, their manufacture and use as pesticides are disclosed. The new compounds correspond to the formula WHEREIN R1 represents halogen or nitro, R2 represents hydrogen or lower alkyl, R3 represents alkyl, alkoxy, alkenyloxy, alkynyloxy, phenyl, amino, monoalkylamino or dialkyl-amino, R4 represents alkyl, alkenyl or alkynyl, and X and Y each represent oxygen or sulphur.
[US3919244A]
Patent IE-45136-L (IE)
Title: Rearing of animals
IPC: A23K50/15
Filed: 1977-04-26
Abstract: Agents containing Salinomycin for oral administration to domestic animals which do not digest cellulose in the rumen, particularly pigs, are disclosed, for instance for the prophylactic treatment of disease and/or for improvement of growth.
[US4260631A]
Patent FI-845083-L (FI)
Inventor: DUTT WILLIAM H
IPC: D21F7/08
Filed: 1984-12-21
Abstract: A paper machine facing, which is composed of polymer synthetic fibres or filaments, which are porous. <IMAGE>
Patent FI-851352-L (FI)
Inventor: SCHNABEL EUGEN
IPC: C12Q1/44
Filed: 1985-04-03
Abstract: Agent for the detection of esterolytic and/or proteolytic enzymes, containing (a) an amino acid ester or peptide ester of a phenol, as the chromogenic enzyme substrate, and (b) an alcohol as the substance which accelerates the enzymatic cleavage of the amino acid ester bond or peptide ester bond of component (a), characterized in that it contains a salt as the accelerating substance.
Patent IE-781018-L (IE)
Title: Splice case
IPC: H02G15/18
Filed: 1978-05-22
Abstract: A cylindrical case for enclosing a cable splice is disclosed which includes a longitudinally split tubular closure member, two end members positionable at either end of the closure member, a gasket of resilient material extending the length of the longitudinal split in the closure member and about the two end member, and a channel member cooperating with upstanding ridges on the closure member at the longitudinal split to secure closure of the case. The gasket includes an elongate, resilient sealing element with an elongate rigid bar extending longitudinally therethrough. The bar includes formed ends which define a slot to receive a fastening element and a ground contact extending from the end of the gasket. Resilient sealing rods also extend laterally from the gasket to define sealing elements about the two end members of the splice case. The gasket is tapered as are the channel members and mechanism is provided on the closure member and on the channel members to enable a forcing of the closure members into interference fit on the case.
[US4181814A]
Patent IE-881536-L (IE)
Title: Fluid retentive microfibre web
IPC: D04H1/413
Filed: 1982-11-23
Abstract: A method of making a non-woven web of melt blown polymeric fibres wherein the melt blown fibres have absorbent particles introduced into the stream of microfibres after the microfibres have been extruded. The absorbent particles are directed into the stream of microfibres whilst the fibres are in a tacky state so that the particles adhere to the fibres.
Patent IE-811745-L (IE)
Title: Hermetic seal for a compressor
IPC: F04B39/04
Filed: 1981-07-30
Abstract: A hermetic seal, primarily for compressors (12) for use in refrigeration of air conditioning systems but having use in apparatus wherein a seal is required between two elements (14, 14) reciprocating substantial distances relative to each other, comprising a bellows having a plurality of convolutions (17, 19, 21) with positive displacement means (25, 26; 27, 28) associated therewith that assures simultaneous movement of most of the convolutions upon rapid acceleration of relative movement between the two elements. This prevents excessive stress and strain on any one or more convolutions or on the end convolutions in particular, as to cause failure thereof, by distributing the stress over a large number of the convolutions rather than just a few at any one instant. The stress in each convolution of the bellows depends upon the natural frequency and spring rates of any given bellows diameter and number of convolutions. Also, the stresses in the various convolutions depend upon the location of and the number of divisions that have positive displacement means for actuation thereof, (engine) speed and piston acceleration. By proper selection of the number of convolutions in each division, which may vary in numbers, it is possible to make a bellows of substantial length wherein the stress level in each bellows convolution will be substantially equal.