baber/WOPTO huggingface dataset:
Patent LU-87110-A1 (LU)
Title: New N-acyl oligopeptide amide derivs. - used in inhibitors of renin, useful for control of hypertension and cardiac insufficiency
IPC: A61K38/00
Filed: 1988-01-20
Abstract: Peptides of formula (I) are new: R6=1-10C alkyl (opt. substd. by 1-5C alkoxy or 6-10C aryloxy); 3-7C cycloalkyl: 3-10C cyclo-alkyl (1-5C) alkyl; 6-10C aryl; 5 or 6 membered heteroaryl contg. 1 or 2 N, O or S or one N plus one O and/or 5; heteroaryl -(1-5C)alkyl; 1-5C alkoxy (opt. substd by 6-10C aryl), R10O(CH2CH2-O)n(CH2)m or the gp. (ii) R10=1-5C alkyl; n=1-20; m=1-5; R=H or acetyl; R7=1-5C alkyl or 6-10C aryl; R8 and R9=H, 1-5C alkyl or 6-10C aryl; R1=H or 1-5C alkyl; B and C=bond or are (iii) but not both bond; R11=hydrophilic or lipophilic aminoacid side chain; D=bond, O, NR, or CHR1; R2=1-10C alkyl; 3-10C cycloalkyl (1-5C) alkyl (opt. ring substd.); 6-10C aryl (1-5C) alkyl; heteroaryl (1-5C) alkyl or R15-S(O)s(CH2)p; R15=H, 1-4C alkyl or benzyl; S=O or 1; p=1 or 2; R3=H, OH, NH2 or OCOR2; R4 and R5=H, 1-5C alkyl (opt. substd.) or -CHR12. COR13; R12=1-5C alkyl, opt. substd. by OH; R13=OH, 1-5C alkoxy, NH2 (opt. substd) aminomethyl benzyl; NR4R5 may also be pyrrolidino, piperidino, morpholino or delta-R14-piperazino; R14=H, 1-5C alkyl, benzyl or R16CO; R16=1-4C alkyl or 1-4C alkoxy -(OCH2CH2)qCH2-; q=2-5; y=SO2,CO, (iv).
Patent MA-27286-A1 (MA)
Inventor: SUAU JEAN-MARC
IPC: C08F2/38
Filed: 2005-01-17
Abstract: The present invention concerns a process for controlled radical polymerisation of acrylic acid and its salts in a reactive medium constituted solely of water. The invention also concerns homopolymers and copolymers of acrylic acid obtained by the polymerisation process. Finally, the invention concerns the use of the said homopolymers and copolymers of acrylic acid in fields of industry such as the paper field and in particular the coating of paper and the mass-filling of paper, the oil field, or the fields of paint, water treatment, detergency, ceramics, cements or hydraulic binders, public works, inks and varnishes, sizing of textiles or the finishing of leather.
Patent MA-28106-A1 (MA)
Title: Compositions immunogenes
Inventor: CLAUDINE ELVIRE MARIE BRUCK
IPC: A61K39/00
Filed: 2006-04-25
Abstract: L'invention concerne une thérapie de combinaison utile en matière de traitement ou de prophylaxie de maladies infectieuses, de cancers, de maladies auto-immunes et d'états connexes.
Patent MA-44815-A1 (MA)
Title: Production in vitro de polyphénols et extraction à partir de cals, de vitroplants et de matériels adultes de caroubier (ceratonia siliqua l.)
Inventor: MENTAG RACHID
IPC: A61K36/483
Filed: 2019-02-07
Abstract: La présente invention fourni un procédé de production in vitro de polyphénols à partir des cals et de vitroplants de caroubier (ceratonia siliqua l.) en utilisant les techniques de la culture de tissus. La présente invention fourni également un procédé d’extraction de polyphénols à partir de cals, de vitroplants et de matériaux issues de plantes adultes de caroubier. Les extraits obtenus, riches en polyphénols, en flavonoïdes et en tannins et possédant une puissante activité antioxydante, sont d’intérêt pour la préparation de compléments alimentaires, de compositions pharmaceutiques, ou de préparations extemporanées à usage alimentaire.
Patent MA-47864-A1 (MA)
Title: Une assise en fondation des constructions pour les préserver lors des mouvements sismiques horizontaux
Inventor: LAMRANI MOHAMMED
IPC: E04H9/02
Filed: 2020-01-06
Abstract: Il s'agit d'un nouvel ouvrage d'infrastructure il interposer entre le sol d'assise et la construction dit "platine parasismiqueneosset", cet ouvrage est constitué de nappes superposées d'aciers inoxydables, les aciers de chaque nappe sont disposés parallèles entre eux, les aciers de chaque nappe sont perpendiculaires à ceux de la nappe adjacente par-dessous ou par-dessus, les nappes sont entrecroisées, les platines couvrent tout le sol d'assise sous la construction, cette platine parasismique permet d'absorber en partie les accélérations horizontales dues aux mouvements sismiques, ainsi on préserve les éléments structuraux de la fatigue due par les secausses telluriques horizontales qui viennent les premières, l'objectif est de donner un laps de temps aux occupants pour quitter la construction en sécurité, de sauver des vies et de sauvegarder les biens immobiliers,
Patent UY-24274-A1 (UY)
Title: Nuevos azepanes inhibidores de la proteína quinasa
Inventor: BARBIER PIERRE
Filed: 1996-07-04
Abstract: Compuestos de la fórmula (I). Los nuevos compuestos, composiciones y procesos como se ha descripto hasta aquí, especialmente con referencia a los ejemplos.
Patent UY-24429-A1 (UY)
Title: Acetidinas
Inventor: MEADOWS MASANDRA DORA
IPC: C07D401/06
Filed: 1997-01-03
Abstract: La presente invención proporciona compuestos de fórmula l, dichos compuestos y sales farmacéuticamente aceptables de los mismos, en la que R es cicloalquilo, arilo o alquilo, estando dicho alquilo opcionalmente sustituido; A es CO o SO2; R1 es fenilo, naftilo, bencilo, tienilo, benzotienilo o indolino, estando cada uno de ellos opcionalmente sustituidos con 1 o 2 sustituyentes; R2 es CO2H, CONR3R4, CONR5, NR5, NR3R4, SO2NR5R6, NR5SO2NR5R6; X es alquenilo C1-C4; X1 es un enlace directo o alquileno C1-C6; y m es 0, 1, o 2. Una composición farmacéutica que contiene un compuesto de fórmula l o una sal y un diluyente o vehículo farmacéuticamente aceptable. El uso de un compuesto de fórmula l o una sal, o composición del mismo para la elaboración de un medicamento para el tratamiento de una enfermedad, producción de un efecto antagonista sobre una taquicinina que actue en el receptor de la neurocinina 1 humana (NK1), neurocinina 2 humana (NK2) o (NK3) o una combinación de dos o más de los mismos, para tratar artritis, psoriasis, asma, el síndrome del intestino irritable, eczema, etc. Un ejemplo de un compuesto de fórmula l es: 1-Benzoil-3-(3,4-diclorofenil)-3-(3-[3-morfolinacetidin-1-il]propil)piperidina.
Patent UY-25236-A1 (UY)
Title: Hidrohalogenuros de 1'-(4-(1-(4-fluorfenil)-1-h-indol-3-il(- 1-butil)-espiro(isobenzofuran-1(3h),4'-piperidina)
Inventor: NIELSEN OLE
IPC: A61P25/08
Filed: 1998-11-06
Abstract: Hidrohalogenuro (en particular hidrocloruro) de 1´-[4-[1-[4-fluorfenil)-1H-indol-3-il]-1-butil]-espiro[isobenzofuran-1(3H),4´-piperidina], e hidratos y/o solvatos del mismo, así como composiciones farmacéuticas que contienen las sales de adición ácida junto con por lo menos un portador o diluyente farmacéuticamente aceptable. Estos hidrohalogenuros son útiles en el tratamiento de trastornos psíquicos y neurológicos, como por ejemplo ansiedad, psicosis, epilepsia, las convulsiones, los trastornos del movimiento, perturbaciones motoras, amnesia, enfermedad cerebrovascular, demencia senil del tipo mal de Alzheimer y mal de Parkinson.
Patent UY-25304-A1 (UY)
Title: Forma hidratada de maleato de rosiglitazona
Inventor: BLACKLER PAUL DAVID JAMES
IPC: A61K31/4439
Filed: 1998-12-15
Abstract: Un hidrato de la sal de ácido maléico de 5-(4-(2-(n-metil-n-(2-piridil)amino)etoxi)bencil)tiazolidin-2, 4-diona, caracterizado porque: comprende agua en el intervalo de 0,4 a 2,5% p/p; y proporciona espectros infrarrojos, rayos x característicos; y un proceso para la preparación de tal compuesto, una composición farmacéutica que contiene tal compuesto y el uso de tal compuesto o composición en medicina.
Patent UY-26425-A1 (UY)
Title: Formulación y método antidiabético
Inventor: PIPER BETH ANNE
IPC: A61P1/00
Filed: 2000-11-02
Abstract: Formulación farmacéutica antidiabética de baja dosis, adaptada para tratamiento de diabetes del Tipo II en pacientes sin experiencia en el fármaco, incluyendo una combinación de metformina (empleada en una cantidad reducida (menos de 900 mg de metformina por día) comparada con la que se emplea en práctica médica generalmente aceptada) y al menos algún otro antidiabético tal como una sulfonil urea, por ejemplo, gliburida y método para tratamiento de diabetes en pacientes similares empleando la formulación anterior para reducir la resistencia a la insulina y/o la excursión de glucosa post-prandial y/o la hemoglobina 1 Ac, y/o el incremento de la insulina post-prandial, por ello tratando la diabetes.
Patent UY-30109-A1 (UY)
Title: Formas farmacológicas en forma de película para usar en la cavidad bucal (obleas)
Inventor: BRACHT STEFAN
IPC: A61P5/34
Filed: 2007-01-24
Abstract: Sistema en forma de película de aplicación bucal transmucosa que contiene: una hormona esteroide del grupo de los andrógenos, los gestágenos y los estrógenos; el 30-70% en peso de una ciclodextrina o de un derivado de ciclodextrina; un formador de película que se descompone en medio acuoso.
Patent UY-30219-A1 (UY)
Title: Método y aparato para procesar troncos
Inventor: KOKKO PEKKA
IPC: A01G23/00
Filed: 2007-03-19
Abstract: Método y aparato para procesar troncos (12). El aparato (1) comprende un nivel de transporte (2) que se extiende esencialmente en la direccion de avance (P) de los troncos, sobre el cual los troncos se disponene para ser transportados en una posicion sustancialmente perpendicular a su direccion de avance (P). En el método, al menos dos unidades miembro de soporte (28), espaciadas una de otra, se disponen debajo del nivel de transporte (2) en una direccion de avance (P) de los troncos (12).
Patent DZ-1360-A1 (DZ)
Inventor: ZIMMERMAN THOMAS
IPC: E21B49/08
Filed: 1989-09-20
Granted: 2004-09-13
Abstract: The apparatus of the present invention relates to a down hole tool capable of extraction of valid samples and making pressure measurements useful in calculating formation permeability. The tool incorporates the features of a straddle packer to allow formation fluid specimens to be taken at large flow rates without depressing the pressure below the formation fluid bubble point. When used in combination with a pressure probe the tool is used to obtain meaningful permeability readings in a larger radius area than previously permitted with known designs. Additionally, the apparatus of the present invention allows flow control during the creation of the pressure pulse which enhances extraction of valid samples and the permeability determination. The apparatus is modularly constructed so that in a single descent of the tool, a pressure profile of the zone of interest can be made, a fluid analysis can be made at each station, multiple uncontaminated fluid samples can be withdrawn at pressures above the bubble point, local vertical and horizontal permeability measurements can be made at each station, a packer module can be set at a location dictated by previous measurements and a large scale pressure build up test can be performed. <MATH>
Patent ES-246901-A1 (ES)
Title: Aniline derivatives
IPC: C07C311/37
Filed: 1959-01-20
Abstract: The invention comprises sulphamoyl anthranilic acid derivatives of the formula <FORM:0898782/IV (b)/1> and their alkali-metal and alkaline-earth metal salts, wherein R1 is halogen, e.g. Cl, Br or F, C1-5 alkyl, e.g. methyl or propyl, C1-5 alkoxy, e.g. methoxy or propoxy, nitro or amino, R2 is hydrogen or a C1-5 alkyl radical, Y is hydrogen, C1-5 alkyl, C1-12 alkanoyl or mononuclear aroyl, e.g. benzoyl and Z is a hydroxy, C1-5 alkoxy, amino or mono- or di-alkylamino radical. The compounds are made by processes involving converting the corresponding carboxylic acids (Z=OH) into the amides and esters (Z=amino or alkoxy), converting a corresponding sulphonyl chloride (obtained by the action of chlorosulphonic acid) into the desired sulphonamide by treatment with ammonia, oxidising an N-acyl-o-toluidine to the corresponding anthranilic acid with potassium permanganate and magnesium sulphate, hydrolysing a corresponding N-acyl compound (Y=alkanoyl or aroyl) to give a product wherein Y is hydrogen, and treating an isatoic anhydride (obtained by condensing a sulphamoyl-anthranilic acid and an alkyl halocarbonate) with ammonia or an amine: a sulphamoyl-N-alkoxycarbonyl anthranilic acid ethyl ester is obtained as a by-product in the latter process and is converted by the reaction with ammonia or an amine into a (2-carboxysulphamoylphenyl)-urea. Sulphamoyl toluidines used as starting materials, i.e. sulphamoyl R1-substituted-o-toluidines bearing an N-alkanoyl or aroyl and optionally also an N-alkyl substituent are made by the action of chlorosulphonic acid and ammonia on the appropriate toluidine. Anthranilic acid derivatives used as starting materials, i.e. 2-carboxy-5-methoxy-N-methyl-acetanilide and 2-carboxy-5-chloro-N-methyl-N-propyl-aniline are made by the action of acetic anhydride and propyl iodide respectively on the appropriate anthranilic acid derivatives. N - Butyryl - and N - lauroyl - 5 - chloro - 2-methyl aniline are made by acylating 5-chloro-2-methyl aniline. 2 - Methyl - 5 - propyl - acetanilide, 5 - chloro - 2 - methyl - N - propyl - acetanilide and 5 - fluoro - 2-methyl-acetanilide are made by acylating the appropriate o-toluidine. 2-Methyl-5-propoxyacetanilide is made by condensing the corresponding 5-hydroxy compound with propyl bromide. 5 - Chloro - 2 - methyl - N - propylaniline is is made by treating 5-chloro-2-methyl aniline with benzenesulphonyl chloride and reacting the resulting N-(2-methyl-5-chlorophenyl)-benzene-sulphonamide with propyl iodide. Pharmaceutical preparations having diuretic and natriuretic properties comprise the above sulphamoyl-anthranilic acid derivatives together with an inert non-toxic diluent, suitably in the form of tablets, pills or capsules for oral administration or in solution in dilute alkali or polyethylene glycol to provide injectable solutions for parenteral administration. Tablets comprising 2 - carboxy - 5 - chloro - 4 - sulphamoyl - aniline starch and magnesium stearate are described.
Patent ES-273985-A1 (ES)
Title: Separators for electrolytic cells
IPC: H01M50/423
Filed: 1962-01-23
Abstract: In a felted battery separator which is less than 0.4 mm. thick at least some of the fibres forming the felt are longer than 25 cm. so that loops are formed in the surfaces of the separator. The separator may be made from continuous fibres, a mixture of cut fibres (less than 3 cm. long) and uncut fibres (greater than 25 cms. long) or wholly from uncut fibres. The fibres may be natural fibres or synthetic fibres, e.g. polyamicle fibres or mixtures of different materials. When continuous fibres are used they are fed from spools to a rolling mill and there is no need to use bonding agent to cause the fibres to stick together. Specification 996,476 is referred to.
Patent ES-294364-A1 (ES)
Title: Multiple-effect evaporation utilizing submerged combustion heat
IPC: C02F1/10
Filed: 1963-12-10
Abstract: A solution of dissolved solids is concentrated in evaporation unit 10, e.g. a multiple-effect evaporator, whence the concentrated solution flows through line 12 to submerged combustion unit 13 where the solution is further concentrated by contact with hot combustion gases to give a slurry, the slurry is conveyed through line 19 to filter or centrifuge 18, the mother liquor is returned via line 21 to unit 13, and the hot gases and vapours, withdrawn from unit 13 through line 22, are used as heating medium in evaporation unit 10. The system may be used to produce distilled water and salt from saline water which is introduced into multipleeffect evaporator 10 through line 9. Distilled water is withdrawn from evaporator 10 through line 11. Compressed air in line 16 is mixed with fuel supplied through line 17, and the mixture is conducted to the burner of unit 13. The hot gases and steam leaving the unit 13 flow through line 22 into the heating element of one of the effects of evaporator 10, and the condensed water is withdrawn through line 23. The now cooled gases are passed through line 24 to turbine 25 for driving air-compressor 15. Salt is discharged from the system via line 20.
Patent ES-344600-A1 (ES)
Title: Improvements relating to the Spinning of Textile Yarns
IPC: D01H4/50
Filed: 1967-08-30
Abstract: A method of piecing up an open-end spinning chamber after yarn breakage or on starting spinning comprises starting the fibre feed, e.g. delivery rollers 32, 33, arranging for the yarn attached to the take-up reams 44, 45 to follow an extended path, e.g. as shown in the chain dotted lines between the delivery tube 40 and the take up means 44, 45 and then shortening the yarn path to the position shown in full line to allow the end of yarn to contact and pick-up the fibres on the collecting surface and drawing off the continuous length of yarn produced. In the form shown when yarn 41 leaves the collecting surface, fibre delivery rollers 32, 33 and the take-up means 42, 43, 44, 45 are immediatly stopped, brakes being applied if necessary. Simultaneously drive to rotor 37 is stopped to allow the rotor to gradually run to rest. After a time delay a bar 49 with a yarn engaging pin 50 is moved horizontally, deflecting the yarn and drawing off the yarn which is still being formed from the collecting surface. Finally the suction through the chamber applied to its casing 39 is switched off. On restarting, the suction pump and rotor drive are first established. Then rollers 32, 33 are started and bar 49 begins to move back to its normal position thus allowing the extra yarn length to be sucked back into the chamber to join the freshly forming yarn. Finally the draw-off rollers 42, 43, and take-up means 44, 45 are started to take up the newly formed thread Microswitches 52, 53 may be operated by an abutment on bar 49 to initiate some of the operations and to limit the movement of bar 49. In Fig. 1 not shown, on yarn breakage the feed rollers (11, 12) and draw-off rollers (19, 20) are stopped while the rotor (15) continues to run at normal speed. The yarn (17) is taken from the delivery tube (18) and passed via a guide (22) to a cutter (23) which cuts the yarn end to a predetermined length. The end is then inserted into the rotor, the yarn passing about guide (22) to follow an extended path. The feed and draw-off rollers are then started and the yarn is pulled from guide (22) by the draw-off rollers. The extra yarn length allows the yarn end to begin picking up fresh fibres before being drawn from the chamber thus piecing is accomplished. In Fig. 2 not shown, the yarn on leaving the delivery tube (18) passes along a pivoted guide tube (28) which is normally in a position such that the yarn in its travel to the draw-off rollers passes along an extended path. When the yarn becomes detached from the fibre collecting surface the resulting drop in tension is sensed by a known device, the drawoff rollers (29, 30) are stopped and the pivoted tube (28) pivoted to clamp the yarn between its end and a stop (31). On restarting the tube (28) is pivotted to a position which shortens the yarn path to allow the end to be drawn back into the rotor and draw-off rollers (29, 30) are started normal spinning is thus resumed. Tube (28) is gradually pivoted back to its "yarn extending" position in readiness for a subsequent piecing operation.
Patent ES-351534-A1 (ES)
Title: A Device for Joining Mitre-Cut or Square-Cut Sections.
IPC: F16B12/50
Filed: 1968-03-13
Abstract: A device for joining recessed or hollow mitre-cut or square-cut sections 1, 2 comprises a right-angled corner piece 3 having two limbs insertable in the ends of the sections and a cylindrical member 5 for location in co-operating holes in each section and associated limb of the corner piece, each cylindrical member containing a screw 6 extending parallel to the cylinder axis and adapted, when advanced, to apply thrust to a displaceable member 8 which is arranged to convert the thrust of the screw into a lateral thrust on the associated limb of the corner piece to pull the sections together. The displaceable member 8 may be a triangular cross-section prism, a hemispherical member or a ball (Figs. 3 to 6, not shown).
Patent ES-353189-A1 (ES)
Title: A Vehicle Seat Construction
IPC: B60N2/50
Filed: 1968-04-25
Abstract: A vehicle seat 1 is supported on a mount 2 supported by a parallelogram linkage 3 and by a compression spring shock absorber unit 4 which is pivotally connected at its ends, and the lower end of the unit 4 can be moved along a path which is perpendicular to the unit to change the force exerted by the unit on the seat. The lower end of the unit 4 has a bolt 20 which is displaced in guide slots 21 in inner cheeks 22 on a base plate 6 by a screw pack 5 comprising a rod 23, Fig. 4, with a male thread 231 screwed into a sleeve 24 with a female thread 241 and a male thread 2411 of opposite hand which is screwed into a nut 26 carried on trunnions 28 mounted on the cheeks 22. The sleeve is rotated by a knob 27 and the rate of adjustment per turn is the sum of the leads of the two equal threads 231, 24". An arm 33 connected to the bolt 20 of the unit 4 passes through a slot in an outer cheek 10 on the base plate 6 and co-operates with a scale 35. The seat 1 is pivoted to a pin 41 having rods 43 which slide in the mount 2 and a pin 45 on the seat is selectively engaged with a plurality of holes 46 in the mount 2.
Patent ES-361681-A1 (ES)
Title: Improvements in piezoelectric ignition devices
IPC: F23Q3/00
Filed: 1968-12-20
Abstract: A piezo-electric igniter has a cylindrical housing 10 roll-formed from a metal plate 100, Fig. 5, having complementary dove-tail cut-outs and projections 104, 103 on opposite longitudinal edges which interengage to form a keyed joint, the plate also having projections 105 which extend radially outwardly of the housing to form stops and depressions 106 extending inwardly of the housing to form stops for a ring 13 carrying spring arms 25 formed with detents 24 which engage the head 22 of a striker 21. A piezo-element carrier 15 is held in one end of the housing by bent-over lugs 109 and a push-button 18 is retained in the other end of the housing by a rolled-over rim 110. Depression of the push-button against a return spring 20 compresses a spring 23 against the striker head 22 until a chamfered edge on the push-button forces apart the detents 24 whereupon spring 23 drives the striker into engagement with the pin 27 of the piezo element.
Patent ES-362065-A1 (ES)
Title: Selective character centering line follow logics
IPC: G06V30/146
Filed: 1969-01-02
Abstract: In pattern scanning apparatus, data signals from a raster scan are consolidated in a selected direction, and detection of predetermined combinations of features in the consolidated data signals causes adjustment of the raster position in a direction at right angles to the selected direction. A character in a line of characters is scanned by a raster of vertical parallel lines to obtain data bits (32 per scan line) which are shifted into a one column (scan line) shift register, each bit being ORed with the correspondinglypositioned bit already in the register to develop a horizontal projection of the character. In case the raster overlaps the next line of characters above or below, the number of black-towhite and white-to-black transitions in the projection is counted in a sequence counter (preset to one), the nature (black or white) of the lowest bit in the projection is stored in a flip-flop, and a black bit counter counts the number of black bits in a black bar (series of consecutive black bits) in the projection to determine if the number lies between 8 and 25, then decrements the count with each black bit in a second bar (if present) to determine which bar is the longer (result stored in a sign flip-flop) and whether the modulus of the difference of the lengths exceeds 3. Logic circuitry responds to these indications and to the shift register direct to cause the raster to move up or down to centre on the character, the shift register being ring-shifted down or up respectively correspondingly, its direct connections to the logic circuitry terminating the movement at the appropriate time.