baber/WOPTO huggingface dataset:
Patent EA-201892343-A1 (EA)
Title: Новые в7-н3 связывающие молекулы, содержащие их конъюгаты антитело-лекарственное средство и способы их применения
IPC: A61K39/395
Filed: 2017-04-13
Abstract: Настоящее изобретение направлено на новые B7-H3-связывающие молекулы, способные связываться с B7-H3 человеческой и нечеловеческой природы, и в частности на такие молекулы, которые являются перекрестно-реактивными с B7-H3 приматов, отличных от человека (например, яванского макака). Изобретение дополнительно относится к B7-H3-связывающим молекулам, которые включают вариабельные домены легкой цепи и/или вариабельные домены тяжелой цепи (VH), которые были гуманизированы и/или деиммунизированы для того, чтобы проявлять сниженную иммуногенность при введении объектам-реципиентам. Изобретение, в частности, относится к биспецифическим, триспецифическим или мультиспецифическим B7-H3-связывающим молекулам, включая биспецифические диатела, BiTE, биспецифические антитела, трехвалентные связывающие молекулы и т.д., которые включают (i) такие B7-H3-связывающие вариабельные домены и (ii) домен, способный связываться с эпитопом молекулы, присутствующей на поверхности эффекторной клетки. Изобретение также относится к фармацевтическим композициям, которые включают любую из таких B7-H3-связывающих молекул, и к способам, связанным с применением любой из таких B7-H3-связывающих молекул при лечении рака и других заболеваний и состояний. Изобретение также, в частности, относится к молекуле, которая включает домен, связывающий B7-H3 человека, гуманизированного антитела против B7-H3 человека, конъюгированной по меньшей мере с одним лекарственным компонентом ("B7-H3-ADC"). Изобретение также относится к фармацевтическим композициям, которые включают такие B7-H3-ADC, и к способам, связанным с применением любого из таких B7-H3-ADC при лечении рака и других заболеваний и состояний.
Patent EA-201990328-A1 (EA)
Title: Способ фильтрации воды
IPC: B01D61/18
Filed: 2017-07-11
Abstract: Способ функционирования фильтрующего блока, содержащего фильтрующий сосуд, содержащий по меньшей мере один глухой фильтрующий элемент, причем фильтрующий элемент или каждый фильтрующий элемент состоит из множества микрофильтрующих или ультрафильтрующих мембран из полых волокон, в котором во время фильтрации подаваемую воду, содержащую взвешенный материал в форме частиц, подают одновременно внутрь полых волокон через оба их конца, и фильтрат удаляют снаружи полых волокон через выпускное отверстие фильтрующего элемента (элементов); и во время обратной промывки вода для обратной промывки подается кнаружи полых волокон через выпускное отверстие фильтрующего элемента (элементов), и в первом цикле обратной промывки вода для обратной промывки, содержащая захваченный материал в форме частиц, отводится изнутри полых волокон из одного их конца; а во втором цикле обратной промывки вода для обратной промывки, содержащая захваченный материал в форме частиц, отводится изнутри полых волокон из другого их конца; и при котором первый и второй циклы обратной промывки можно выполнять в любом порядке.
Patent EA-201990588-A1 (EA)
Title: Новые пептиды и каркасы для применения в иммунотерапии плоскоклеточной карциномы головы и шеи и других видов рака
IPC: C07K14/47
Filed: 2017-08-24
Abstract: Настоящее изобретение относится к пептидам, белкам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным пептидным эпитопам T-клеток, в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые могут, например, служить в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы, или стимулировать T-клетки ex vivo с их перенесением в организм пациента. Пептиды, связанные с молекулами главного комплекса гистосовместимости (MHC), или пептиды в отдельности могут быть также мишенями антител, растворимых T-клеточных рецепторов и других связывающих молекул.
Patent EA-202191802-A1 (EA)
Title: Способ изготовления строительного элемента и строительный элемент
Filed: 2020-01-09
Abstract: Изобретение относится к способу изготовления строительного элемента (10), включающему в себя нанесение первого слоя (1) на первую поверхность основы (2), причем первого слоя (1), включающего в себя смесь из связующего, по меньшей мере одного наполнителя и тонких непигментных когезионных частиц, причем количество тонких непигментных когезионных частиц в смеси может составлять от 0,05 до 9 мас.% смеси, и приложения тепла и/или давления к первому слою (1) и/или к основе (2), образуя тем самым строительный элемент (10). Изобретение также относится к такому строительному элементу (10).
Patent EA-202191996-A1 (EA)
Title: Способы контроля или предупреждения заражения растений сои фитопатогенными микроорганизмами
Filed: 2020-01-20
Abstract: Настоящее изобретение относится к способам контроля или предупреждения заражения сои фитопатогенными микроорганизмами семейства Corynesporascaceae, в частности Corynespora cassiicola, включающим применение по отношению к сельскохозяйственной культуре растений, месту их произрастания или материалу для их размножения соединения в соответствии с формулой (I)где R1, R2, R3, R4, R5, Y, A, B определены в данном документе.
Patent ES-2197817-A1 (ES)
Title: Method of obtaining a buffered hypertonic solution and solution thus obtained
Inventor: TABUENCA NAVARRO DANIEL
IPC: C01B25/30
Filed: 2002-06-10
Abstract: The invention relates to a method of obtaining a buffered hypertonic solution and the solution thus obtained, said solution being of the type of saline solutions with a constant pH which can be used in therapeutics. The inventive method consists in adding phosphoric acid (3) and sodium hydroxide (4) to deionised water (2) in a reactor (1), simultaneously but at different speeds, thereby producing an aqueous solution of disodium phosphate and monosodium phosphate in a proportion of 1:2 in said solution.
Patent ES-2253031-A1 (ES)
Title: Low voltage devices designed to low voltage electrical outlets base plate
Inventor: AUBERT CAPELLA JOAQUIN
IPC: H01R24/10
Filed: 2003-06-17
Abstract: They consist in an external plate (1) which is fit under pressure on a frame (3) by means of prongs (4) which show inclined protrusions to allow they are easily removed. The frame (3) possesses a rectangular central opening (9) which will allow to locate one or more mechanisms while the external plate is provided with one or several related openings (8, 8a, 8b) depending on the mechanisms to be installed that the body (18, 38, 49, 53) shows, the application of base plate of an electrical outlet with two poles, base plate of an electrical outlet with two poles and earth connection, base plate of an electrical outlet in a variation with two pairs of poles with its related earth connection, in the so-called duplex arrangement and base plate for a so-called electrical outlet in duplex arrangement provided with differential GFCI, all those base provided with a safety plate . The external plate possesses openings corresponding with the central rectangular opening of the frame, the sizes and arrangement thereof changing depending on whether whether, two or one mechanism are installed. The base of the body (18) shows cylindrical appendages (21) in the interior of which there are the body for the contacts (40, 40') connection, being provided with openings (21a) (42) for the conductors. As electrical outlet with two poles and earth connection there is a third appendage (21). Under the cover (22) is located the rectangular safety plate (29) having a base with double initial position, as a rocker, which is located a cylindrical helical spring (30) which keeps it at its initial position, only when two prongs are entering at same time the plate is moved sideways overcoming the action of the spring. The contacts of the poles consist in a base plate fastened by means of a rivet (40a) on the connection body (40) and from which sides two upright sheets (39) rise obtained by die cut and folded as a clamp. The contacts of the earth connection consist in a base plate (27a) having the shape of a lyre. As duplex the dimensioning of the body (49) and its cover (48) is identical to that of the opening of the frame (9), there is only one mechanism on the frame. As duplex, it shows two sets of contacts for the two poles and it earth connection, only three connection bodies being available. As duplex equipped with differential, the frame (56) has cylindrical buttons (59) like a clamp on which holes (58) of the side flanges (57) of the mechanism cover will fit.
Patent ES-2289917-A1 (ES)
Title: Breathable and impermeable sport for use by e.g. men, has breathable and impermeable bases inserted into openings which are made in shoe body and side panels, respectively, and membranes injected over elastomers
Inventor: ALVAREZ GINES JUAN ANTONIO
IPC: A43B7/12
Filed: 2006-01-27
Abstract: The shoe (1) has a breathable and impermeable base (2) inserted into an opening which is made in a shoe's sole. Another breathable and impermeable base is inserted into another opening which is made in side panels of a shoe. The bases are made of elastomers and are attached in place by contact glue. The bases have membranes which are injected over the elastomers. Perforations (5) are provided in an area which coincides with the base (2). A perforated sheath covers an inside of a shoe body. The membranes are made of a material based on microscopic polyethylene fibers.
Patent ES-2292341-A1 (ES)
Title: Eicosapentaenoic acid purification method involves carrying out enzymatic reactions of esterification using lipase obtained from extracts of fish and microalgae
Inventor: RAMIREZ FAJARDO ANTONIO
IPC: C11C1/00
Filed: 2006-03-13
Abstract: The eicosapentaenoic acid purification method involves carrying out enzymatic reactions of esterification using lipase obtained from extracts of fish and microalgae. A dimensionless efficacy factor is also used for quantifying effectiveness of lipases for concentrating and simultaneously recovering a polyunsaturated fatty acid in the fraction of free fatty acids.
Patent ES-2298088-A1 (ES)
Title: Intelligent outdoor cabinet
Inventor: LEE LIN HUNG
IPC: H04Q1/02
Filed: 2005-06-17
Abstract: An assembled telecommunication exchange cabinet, comprising a hollow body and a base, wherein the body comprises a set of front doors, left and right side doors, a top cover and a heat sink device. A plurality of inlets are disposed on the bottom surface of the body, and a telecommunication exchange device and terminal boards are accommodated inside the body. The body accommodates a Digital Subscriber Line Access Multiplexer and a telecommunication exchange device, which in turn, are connected to the corresponding terminal boards. The left and right side doors and the top cover can be subsequently opened separately after the set of front doors is opened. In addition, the heat sink device of the body is disposed under the top cover. The base of the cabinet is removeably attached to the body and at least one battery holder is further disposed inside the base to accommodate at least one spare battery.
Patent ES-2327202-A1 (ES)
Title: Method for recovering gold using hollow-fibre membranes and dispersion-based back-extraction
Inventor: SASTRE REQUENA ANA MARIA
IPC: C22B3/26
Filed: 2008-04-25
Abstract: The invention relates to a method for recovering gold using hollow-fibre membranes and dispersion-based back-extraction in the presence of one or more of the following metals: Zn, Ag, Ni, Fe and Cu, in an aqueous cyanide medium.
Patent ES-2347406-A1 (ES)
Title: Mould for making balls with integral shafts for valves by centrifugal moulding
Inventor: GONI USABIAGA INIGO
IPC: B22D13/10
Filed: 2009-04-27
Abstract: The present invention relates to a mould for making balls with integral shafts for valves by centrifugal moulding, made up of two complementary half-bodies (1 and 2) which are assembled and placed on a rotary mount, each of said half-bodies (1 and 2) forming, inside, a central cavity (5) from which there extend channels (6), such that the two half-bodies (1 and 2) between them define a central receptacle with the shape of the ball bodies to be moulded and ducts for forming the shafts associated with said ball body.
Patent JO-P20210085-A1 (JO)
Title: Anti-TNF?-antibodies and functional fragments thereof
Inventor: TEA GUNDE
Filed: 2021-04-22
Abstract: The present invention relates to antibody molecules and functional fragments thereof, capable of binding to tumor necrosis factor alpha (TNF?), to processes for their production, and to their therapeutic uses.
Patent JO-P20220114-A1 (JO)
Title: Ultra-large marine submersible transport boats and arrangements for transportation of aqueous bulk liquids, including fresh water
Inventor: CHELARU SILVIU DORIAN
Filed: 2020-10-28
Abstract: Ultra-large marine submersible transport boats and arrangements for aqueous bulk liquids transportation, including fresh water and irrigation drainage, from specifically configured supply stations to specifically configured delivery stations. Boats present rigid hydrodynamic shaped double-walled submersible hulls incorporating a plurality of inside-reinforced impervious ballast chambers and also present radial reinforcing elements and hollow interior cavities that enclose collapsible bulk liquid bladders for transporting bulk liquids. Hulls can be made of reinforced concrete. Hull openings permit seawater circulation, avoiding transportation of bulk ballast seawater. Submersible cruising reduces structural loads and drag. An on-board hydro-pneumatic ballasting system adds to and removes reusable hull ballast water from, the ballast chambers controlling the hull’s depth, pitch, and roll. Propulsion, steering capabilities, and detailed arrangements and methods for loading, unloading, and transporting bulk liquids are presented. Hull manufacturing is done on marine floating platforms using onshore precast panels. Maintenance and end of life procedures are detailed.
Patent RS-20160116-A1 (RS)
Title: Instrument for corps status measurement based on optical sensor
Inventor: MATOVIĆ JOVAN
IPC: G06Q99/00
Filed: 2016-02-25
Abstract: The present invention relates to apparatus for measuring of crop conditions by means of optical method. The apparatus consists from optical sensor (1) connected via a USB, Bluetooth or Wi-Fi protocol (2) with a cell phone (3). Cell phone processes the data gathered from the sensor and calculates the optimal agrotechnical correction measures. In case of complex data processing, the cell phone automatically connects a remote expert (4), via GSM network or Internet. Remote expert includes additional analysis and sends back recommendations to the user via the same network. The optical sensor contains single multispectral light source, an optical multichannel receiver, circuits for communication with the cell phone, autonomous power supply and additional power supply mobile phone.
Patent SG-99373-A1 (SG)
Title: Inductor-capacitor resonant rf switch
Inventor: LIHUI GUO
IPC: H01P1/12
Filed: 2001-08-30
Abstract: A new inductor-capacitor resonance RF (LCR-RF) switching device is achieved. The device comprises a microelectronic mechanical switch and a spiral inductor. The microelectronic mechanical switch comprises, first, a first dielectric layer overlying a substrate. A down electrode overlies the first dielectric layer. A second dielectric layer overlies the down electrode. An up electrode overlies the down electrode with the second dielectric layer therebetween. A bridge post overlies the first dielectric layer and does not contact the down electrode or the up electrode. Multiple bridge posts may be used. Finally, a membrane is suspended over said down electrode. One end of the membrane is fixed to the top of the bridge post. An electrostatic potential between the membrane and the down electrode will cause the membrane to flex down toward the down electrode. This flexing of the membrane will cause the capacitance of the switching device to vary. The spiral inductor comprises a metal line configured in a spiraling pattern with a first end connected to the bridge post and a second end forming an output node. A dual damascene method to form the LCR-RF switch is also achieved.
Patent SG-111285-A1 (SG)
Title: Feature optimization using enhanced interference mapping lithography
Inventor: LAIDIG THOMAS
IPC: G03F1/00
Filed: 2004-11-01
Abstract: Disclosed concepts include a method of, and program product for, optimizing an intensity profile of a pattern to be formed in a surface of a substrate relative to a given mask using an optical system. Steps include mathematically representing resolvable feature(s) from the given mask, generating a mathematical expression, an eigenfunction, representing certain characteristics of the optical system, modifying the mathematical the eigenfunction by filtering, generating an interference map in accordance with the filtered eigenfunction and the mathematical expression of the given mask, and determining assist features for the given mask based on the interference map. As a result, undesired printing in the surface of the substrate may be minimized.
Patent TR-201611556-A1 (TR)
Title: Oral farmasöti̇k formülasyonlar
Inventor: BÜLENT KARAAĞAÇ
IPC: A61P11/00
Filed: 2016-08-16
Abstract: Mevcut buluş; astım, kronik bronşit, kronik obstruktif akciğer hastalığı (KOAH), amfizem ve bronkospazm gibi akciğer hastalıklarının profilaktik ve/veya semptomatik ve/veya terapötik tedavisinde kullanılmak üzere mukolitik özellikteki uygun etken madde ve/veya farmasötik olarak kabul edilebilir türevlerinin, ksantin grubundaki uygun etken madde ve/veya farmasötik olarak kabul edilebilir türevleri ile kombine tedavisini içeren farmasötik bileşim/ler ile ilgilidir.
Patent TR-202011405-A1 (TR)
Title: Bir levha şekillendirme sistemi.
Inventor: FAHRETTİN ÖZTÜRK
IPC: H05B6/10
Filed: 2020-07-17
Abstract: Bu buluş, bir gövde (2), birbiriyle karşılıklı kalacak şekilde ve birbirine doğru hareket edebilir şekilde gövde (2) üzerinde yer alan ve şekillendirme işlemi için kuvvet uygulayan en az bir alt çene (3) ve/veya en az bir üst çene (4), alt çene (3) ve/veya üst çene (4) tarafından üzerine uygulanan kuvvete karşı mukavemet gösteren ve alt çene (3) ve/veya üst çene (4) üzerinde yer alan en az iki plaka (5), her bir plaka (5) üzerinde birbiriyle karşılıklı kalacak şekilde yer alan ve ısıl izolasyon sağlayan en az iki izolasyon levhası (6), alt çene (3) ve/veya üst çene (4) üzerinde yer alan izolasyon levhası (6) üzerinde konumlandırılan ve birbiri içerisine form uyumlu olacak şekilde yerleşen en az bir erkek kalıp (7) ve en az bir dişi kalıp (8), erkek kalıp (7) ve dişi kalıp (8) arasında kalarak ve ısı verilerek şekillendirilen en az bir iş parçası (9) ile ilgilidir.
Patent TR-202019133-A1 (TR)
Title: Metali̇k parçaciklarin yakalanmasi i̇çi̇n ayri bi̇r manyeti̇k elemana sahi̇p bi̇r yakit enjeksi̇yon valfi̇
Inventor: MUSTAFA SARIGÖZ
IPC: F02M37/32
Filed: 2020-11-27
Abstract: Mevcut buluşta, merkezi bir boylamasına eksene (X) sahip bir valf gövdesini (90), yakıt geçişini sağlayan bir valf manşonunu (30), valf manşonu (30) içinde konumlanan ve merkezi boylamasına eksen (X) boyunca hareket edebilen bir valf iğnesini (20) ve valf gövdesi (90) ve valf manşonu (30) arasında valf manşonuna (30) göre çevresel olarak konumlanacak şekilde adapte edilen bir yakıt filtresini (50) içeren, içten yanmalı motorların yakıt enjeksiyon sistemleri için bir yakıt enjeksiyon valfi (100) ortaya konmaktadır. Yakıt enjeksiyon valfi (100), ilâve olarak, valf manşonuna (30) göre çevresel olarak konumlanacak şekilde adapte edilen ve yakıtın akışındaki metalik parçacıkların (60) yakalanması için valf manşonu (30) ve yakıt filtresi (50) arasında konumlanan silindirik-şekilli bir manyetik elemanı (10) içermektedir
Patent AR-022420-A1 (AR)
Title: Composiciones en barra que contienen tensioactivos anfoteros solidos
IPC: C11D3/12
Filed: 2000-01-26
Abstract: Composiciones en barra para la higiene personal, en particular, aquellas composiciones que comprenden; (1) tensioactivos anionicos formadores de espuma(por ejemplo, isetionato de acilo sodico o jabon de ácido graso); (2) tensioactivos anfoteros solidos específicos, menos higroscopicos (por ejemplo, N-lauril-iminodipropionato disodico). Incorporacion de niveles significativos del mencionado tensioactivo antotero solido en las composiciones en barra específicas,efectos de lograr una mayor suavidaden la piel y propiedades mejoradas de la barra para el consumidor. Ventajas de emplear tensioactivos anfoteros solidos,menos higroscopicos, para reducir las dificultades de procesamiento en los procesos de extrusion, y de extrusion modificados.
Patent AR-024006-A1 (AR)
Title: Composiciones grasas; metodo para prepararlas, y uso de las mismas
IPC: A23L1/18
Filed: 2000-05-17
Abstract: Se describen composiciones grasas que contienen un aceite vegetal y un compuesto de cera derivada de plantas que tienen un punto de fusion de por lo menos46sC. También se describen productos alimenticios y cosméticos que contienen talescomposiciones grasas.
Patent AR-025763-A1 (AR)
Title: Metodos y sistemas para el tratamiento del tejido enfermo con composiciones antiinfecciosas
IPC: A61P17/10
Filed: 2000-09-22
Abstract: La presente se relaciona con un método destinado al tratamiento de los tejidos epiteliales enfermos, tales como los herpes labiales y otras complicacionesque resultan de los trastornos como el herpes y similares. El método de la invencion combina unagente activo antimicrobico y/o antiinfeccioso en un portador,con la friccion vigorosa del tejido epitelial enfermo, para el tratamiento topico del mismo en condiciones que resulten suficientes para lograr una mejoraclínicamente discernible del tejido epitelial enfermo. El agente activo antimicrobico y/o antiinfeccioso preferido es un organohaluro, tal como un compuestode amonio cuaternario, con preferencia, cloruro de benzalconio. El método de la presente también puede usarse con relacion a una configuracion preferida delaplicador.
Patent AR-026914-A1 (AR)
Title: Distribuidor de medicamento
IPC: B65D83/36
Filed: 2000-12-07
Abstract: Se proporciona un distribuidro de medicamento que comprende un recipiente para medicamento que tiene un mecanismo distribuidor; un asiento para recipiente,para recibir el recipiente; una estacion de anclaje; y una conexion entre el asiento para recip iente y la estacion de anclaje, capaz, al deformarse, de moverel asiento para recipiente, con relacion a la estacion de anclaje, a fin de accionar el mecanismo distribuidor. La conexion se puede formar reversiblemente enrespuesta a la aplicacion de e nergía no mecánica a la misma. Laa energía no mecánica puede comprender energía térmica, energía de corriente eléctrica, energíade campo eléctrico o energía de campo magnético.
Patent AR-031400-A1 (AR)
Title: Dispositivo de seguridad en el acceso de monedas al validador de un telefono publico y similares
Inventor: MARTIN GOMEZ DAMASO
IPC: G07F1/02
Filed: 2001-09-20
Abstract: El dispositivo incluye tres modulos (1), (2) y (3) el primero de ellos con una ranura (4) para introduccion de la moneda (5), mientras que el modulo, que se fijo al igual que el anterior, presenta una ranura (6) para el acceso de la moneda al correspondiente validador (9) del teléfono, siendo el modulo (3) movil y dotado de una ranura (8) susceptible de enfrentarse a la ranura (4) y a la ranura (6), quedando en desfase respecto a la otra, para permitir la introduccion de la moneda y/o acceso al validador (9), impidiendo la introduccion de elementos fraudulentos a través de la ranura opuesta del paso de la moneda. El dispositivo incorpora medios de deteccion de presencia (16) de la moneda (5) y medios de deteccion de posicion (18) que posibilita regular de manera precisa el movimiento del modulo movil (3).
Patent AR-034231-A1 (AR)
Title: Composicion farmaceutica que contiene mosaprida y pancreatina
Inventor: VERGEZ JUAN AUGUSTO
IPC: A61K31/5375
Filed: 2002-05-20
Abstract: Una composición farmacéutica que contiene mosaprida, pancreatina y opcionalmente simeticona y es utilizada para el tratamiento, prevención o alivio de los síntomas de un desorden gastrointestinal. La composición farmacéutica es provista en una forma de dosificación.