baber/WOPTO huggingface dataset:
Patent JP-H10500870-A (JP)
Inventor: CHABERT PIERRE GABRIEL
IPC: B64B1/58
Filed: 1995-04-27
Abstract: The balloon (1) has a flexible outer surface (1) which is connected an electric cable with an outer sheath (27). A sealed connection through the balloon wall is made by an outer plate (4) with inner ring and sealed connections (13). Nut connections (28) on the outer wall allow connection to an inner section. The cable connects a power source on the ground to a light in the centre of the balloon. An actuation device inside the balloon consists of a spring (7) which is tensioned by a flexible connector and connected to the loop (17) of a two-sided pin (19). Switches (25) are positioned between the power source and the light. A wire (5) links part of the surface and the actuator which is positioned at another location at the surface periphery. The pin has a sliding holder (24) and an inner spring (15). The pin base (21) is clear of the switch (26) when the balloon is inflated, but pushes the switch closed when the balloon is deflated, switching off the electricity. <IMAGE>
Patent JP-2001506890-A (JP)
IPC: A61L2/10
Filed: 1997-12-23
Abstract: The proposal is for a device with at least one surface layer (1) made from a semiconductor material (4) having an inner side (15), which rests on a support (3), and a disinfectable and/or oxidizing outer side (2), and with a UV radiation source (6), in which device the support (3) conducts light, UV radiation (13) from the UV radiation source (6) is input directly on to the inner side (15) of the semiconductor material (4) via the light-conducting support (3). The light-conducting support (3) and the surface layer (1) of the semiconductor material (4) lying thereon can be applied to the surface of a piece of equipment which is to be disinfected or may even form this piece of equipment.
Patent JP-H09512934-A (JP)
IPC: G07C15/00
Filed: 1995-05-02
Abstract: A promotional game wherein prizes are automatically and randomly awarded upon presentation of multiple tokens bearing machine readable codes. The random generation of prize awards will take place after the multiple inputs of machine readable codes include a set of inputs which match a preselected set of actuating codes.
Patent JP-H10502769-A (JP)
Title: フレキシブルな支持構造体を有する高出力固定ｘ線ターゲット
IPC: H01J35/08
Filed: 1996-04-16
Abstract: (57)【要約】
段差形状の高Ｚボタン20を有するＸ線デバイスの固定ターゲットアノード10が与えられる。ボタン中央のＸ線生成部の直径を最小化し，そこから伸張し中央のほぼ２倍の直径を有する薄いリップを取り付けることにより，内部応力及びインターフェース応力が最小化される。ボタン／基板アセンブリを支持しかつ加熱中に基板が半径方向に膨張するに従い最小の抵抗を与えるべくフレキシブルな構造が与えられ，それによってターゲット上に導入された応力が最小化され支持ターゲットの疲労及び破損が防止される。
Patent JP-2002514317-A (JP)
Title: 多重パックアクティブデバイスレセプタクル
IPC: G02B6/42
Filed: 1998-02-02
Abstract: (57)【要約】
光検出器、またはソリッドステート光源などの、個々のアクティブデバイス(２１０)において１つ以上の光ファイバを終端するための多重レセプタクルパック(３００)。このパック（３００）は、ハウジング（３０４）、終端固定具(１１０)、およびアクティブデバイス（２１０）を含む。ハウジング（３０４）は、１つ以上の光ファイバの終端部分を収容するための開口部（３０２）と、閉位置に付勢される開口部に配置され、光ファイバプラグ（１２）を着脱自在に収容するためのラッチ（３０８）およびハウジング（３０４）の内部へのアクセスを可能にする脱着可能なプレートを有するドア（３０６）とを有する。終端固定具（１１０）とアクティブデバイス（２１０）とは、ハウジングの多重レセプタクル（３０２）のそれぞれの内部に取り付けられた個々の基材（２０８）に搭載されても良い。
Patent JP-H11504913-A (JP)
Title: アザシクロアルカン誘導体、その製造および治療への適用
IPC: C07D491/04
Filed: 1996-04-12
Abstract: (57)【要約】
一般式（Ｉ）：
 ［式中、Ｒ 1 およびＲ 2 は水素原子、アルキル基またはフェニル基を表すか、またはＲ 1 およびＲ 2 が一緒になってオキソ基を形成する。Ｒ 3 は水素原子またはアルキル基であるか、またはＲ 3 はメチレン基を形成する。Ｒ 4 は芳香族基であるか、またはＲ 3 がメチレン基を形成する時には、Ｒ 4 はフェニレン基を表し、その炭素原子１個がＹに結合し、その炭素原子に隣接する別の炭素原子が該メチレン基に結合する。Ｒ 5 は基ＯＲ 7 （ここにＲ 7 は水素原子またはベンジル基である）または基Ｎ 4 −メチルピペラジニルであるか、またはそうでなければ基ＮＨＲ 8 （ここにＲ 8 はヒドロキシル、ピリジニルメチルまたはフェニルメチル基である）のいずれかである。Ａは所望なら置換されていてもよい芳香環である。ｎは１または２である。ＸはＣＨ、Ｏ、またはＮである。およびＹはＣＨ 2 、ＯまたはＳである］で示されるアザシクロアルカン誘導体、その製法および治療へのその適用。
Patent JP-2001511165-A (JP)
Title: イミン及びエナミンの水素化
IPC: C07C209/84
Filed: 1998-01-26
Abstract: (57)【要約】
イミン又はエナミンＩのグループの化合物を、ニトリルIIIの存在下にアミンIIに水素化する方法で、その際上記ニトリルIIIを実質的に水素化することなく行う方法であって、化合物Ｉ及びニトリルIIIを含む混合物を、触媒IVの存在下に水素を含むガスと反応させることを特徴とする方法。
Patent JP-2001502192-A (JP)
IPC: A61F2/88
Filed: 1997-03-27
Abstract: PCT No. PCT/DE97/00649 Sec. 371 Date Sep. 23, 1998 Sec. 102(e) Date Sep. 23, 1998 PCT Filed Mar. 27, 1997 PCT Pub. No. WO97/36556 PCT Pub. Date Oct. 9, 1997The invention concerns a stent 1 for the bracing and/or holding-open of a body cavity having a tube 2 made from an elastic material, a tubular weave 3 comprising filaments 5 seating in close adjacency to the outer surface of the tube 2 as well as a coating 4 applied to the outer surface of the tube 2 which attaches the weave 3 to the outer surface of the tube 2. The coating 4 is adapted to have a structured outer surface dominated by the weave 3. The stent 1 in accordance with the invention can be produced economically with adjustable restoring forces and facilitates a secure placing within the body cavity. Means for preventing drifting within the body cavity can also be introduced onto outer surface of the stent.
Patent JP-2001511016-A (JP)
Title: 大動脈特異的および横紋筋特異的な筋肉細胞におけるアイソフォームをコードする単一遺伝子、およびその使用
IPC: C12N5/10
Filed: 1998-02-06
Abstract: (57)【要約】
大動脈で選択的に発現される遺伝子-1（APEG-1）、および横紋筋で選択的に発現される（SPEG）ポリペプチド、APEG-1/SPEGをコードする遺伝子の転写をコードし調節するDNA配列、血管の損傷を診断する方法、平滑筋細胞特異的な発現を付与する方法、ならびに血管の損傷部位でAPEG-1のレベルを上昇させることによって平滑筋細胞の増殖を阻害する方法について開示する。
Patent JP-2001514677-A (JP)
Title: 架橋形成性の重合性組成物
IPC: C08G75/04
Filed: 1998-01-19
Abstract: (57)【要約】
芳香族ジ−またはポリ−ビニルモノマー、ジ−またはポリチオール化合物、および歪み減少剤の有効量を含有する架橋形成性の重合性注型用組成物。
Patent JP-2001516419-A (JP)
Title: 逃し給気調整弁の制御装置
IPC: F02B33/44
Filed: 1997-11-28
Abstract: (57)【要約】
内燃機関（１）のチャージャの逃し給気調整弁（１３）の制御装置において、逃し給気調整弁（１３）が吸気管（２）内の圧縮器（９）を橋絡する逃し給気調整−導管（１２）内に配されており、逃し給気調整弁（１３）は、絞り弁（４）の下流側の吸気管圧力により制御可能である。逃し給気調整弁（１３）の確定的開閉動作を確保するため、逃し給気調整弁（１３）に、付加的制御圧力（１７）が供給可能であり、該付加的制御圧力（１７）により、逃し給気調整弁（１３）を吸気管圧力（ｐｖｄｋ）に無関係に開放し得るように構成されている。
Patent JP-H11512887-A (JP)
IPC: H01L41/08
Filed: 1997-05-14
Abstract: A bending transducer has a piezoelectret carried on a substrate of electrically insulating material. An electrically conductive coating, such as a foil, a grid foil, a grid mesh, or mutually parallel strips, connects the inner electrode of the piezoelectret to the substrate and forms electrical contact with the inner electrode at a number of points. The bending transducer is particularly suited for driving a drafting, weaving or knitting machine in the textile industry.
Patent JP-H11509780-A (JP)
Title: 空気浄化フイルタ装置
IPC: B01D53/04
Filed: 1997-05-16
Abstract: (57)【要約】
空気浄化フイルタ装置１は、空気の入口５と出口７とを持つハウジング３からなる。フイルタ要素１１を通して入口５から出口７に至る方向Ｄの空気流を起こす空気移送手段９が設けられる。フイルタ要素１１は、酸性又は塩基性水溶液を浸漬させた、吸収性のある繊維質材料より形成された少なくとも１個のフイルタエレメントからなる。特定の実施例においてフイルタ要素は２個のフイルタユニット１３、１５とを連続して配設したものからなり、その内、フイルタユニット１３は酸性水溶液を浸漬させた材料からなり、フイルタユニット１５は塩基性水溶液を浸漬させた材料からなる。所望により、少なくとも１個のフイルタユニットに、アルカリ金属湿潤剤（例えばカリウムホルマート）及び／又は尿素及びアルカノールアミンによって構成されるグループの中から選択された少なくとも１つの有機アミン化合物（例えば３−ヒドロキシメチルアミノメタン）を付加的に浸漬させる。又少なくとも１つのフイルタにｐＨ表示機能を組み込むことも出来る。
Patent JP-2000511635-A (JP)
Title: 流体サンプリング装置
IPC: A61B5/155
Filed: 1997-02-27
Abstract: (57)【要約】
本発明は、穿孔可能な管体から流体をサンプリングする装置（１０）であって、穿孔可能な管体（１２）を受容するようにされた管体穿孔部（２４）と、クランプ（２６）とを有する細長いハウジング（１４）と、細長いハウジング（１４）の内部に取り付けられる針保持部（４０）と、流体が流れるようにされた針（４８）とを備え、針（４８）が両端方向に針保持部の外に延出する部分を有するように針保持部（４０）に固定され、針の第１先端部（５２）が尖鋭化され、かつ、管体穿孔部が針（４８）の第１先端部（５２）に使用者の指が偶然に接触することを実質的に防止するように、第１先端部が管体穿孔部（２４）からはみ出すことなく管体穿孔部の内方に突出し、クランプ（２６）は穿孔可能な管体を管体穿孔部内に把持することにより穿孔可能な管体を針の第１先端部に押し付けて第１先端部が穿孔可能な管体を穿孔するように構成したことを特徴とする装置（１０）を開示する。
Patent JP-2002511138-A (JP)
Title: シングルパス複式モード集積回路テスタ
IPC: G01R31/319
Filed: 1998-04-28
Abstract: (57)【要約】
集積回路テスタ（１０）は、それぞれが入力されたベクタシーケンスに応答して被測定デバイス（ＤＵＴ）（１１）の個別のターミナルにおいて一連の作業を実施する一組のピンエレクトロニクス回路（２０）を有している。そのような作業は、ＤＵＴのターミナルにテスト信号を送って、そのターミナルにおけるＤＵＴターミナル出力信号の状態を確認することを含んでいる。それぞれのピンエレクトロニクス回路は、二つのモード、すなわち、通常モードと複式モードのいずれかで作動することができる。テストは、一組の連続するテストサイクルで構成されている。通常モードで作動するとき、ピンエレクトロニクス回路は、前記連続して入力されるベクタのそれぞれを前記テストサイクルのうちの単独のサイクル中に実行されるべき作業を定義するものとして解釈する。複式モードで作動するときは、ピンエレクトロニクス回路は連続して入力するベクタのそれぞれを二つの連続するテストサイクル中で実施されるべき作業を定義するものとして解釈する。
Patent MD-20060040-A (MD)
Title: Process for electrolytic iron deposition onto cylindrical surfaces
Inventor: CROITORU DUMITRU
IPC: C25D21/10
Filed: 2006-01-26
Abstract: The invention relates to galvanics and may be used for plating the parts cylindrical surfaces. The process for electrolytic iron deposition onto cylindrical surfaces is realized by electrolyte containing 400à600 g/L of FeCl2?4H2O at the temperature of 30à40?C and the cathodic current density of 30à40 A/dm2, at the same time into the electrolyte it is added 50à200 g/L of microabrasive powder, at the anode rotation with a velocity of 400à2500 rev/min.
Patent NZ-225021-A (NZ)
Title: Leukotriene antagonists and medicaments
Inventor: FRAZEE JAMES SIMPSON
IPC: C07C317/04
Filed: 1988-06-14
Abstract: Compounds of formula: <CHEM> in which, inter alia q is 0 to 2, R1 is (L)a-(CH2)b-(T)c-M wherein a and ca are 0 or 1, b is 3 to 14, L and T are independently O, S or CH2; and M is C1-4 alkyl, ethynyl, CF3, isopropenyl, furanyl, thienyl, cyclohexyl or optionally substituted phenyl; R2 and A are H, CF3, alkyl, alkoxy, halogen, OH, NO2, or NH2 or R1 and A are H and R2 is (L)a-(CH2)b-(T)c-M as above; y is COR3 or (CHX)n(CH2)p-Z wherein R3 is OH, NH2, aryloxy or alkoxy, n is 0 or 1, p is 0, 1 or 2; X is H, OH, alkyl, alkoxy or F, Z is COR3 or tetrazolyl; R is (CR5R6)dW, R5 and R6 are H or alkyl and W is an optionally substituted phenyl, pyridyl or pyrimidiyl group, intermediates and processes for their preparation and their use in therapy as leukotriene antagonists.
Patent NZ-228457-A (NZ)
Title: Cooling of molten filaments in spinning machine: maintenance of uniform cooling rate
Inventor: EIJI KATOU
IPC: D01D5/088
Filed: 1989-03-22
Abstract: A method for cooling molten filaments in a spinning apparatus where, a plurality of molten filaments (2) extruded from a die (1) are cooled by cooling air blown out from a cooling apparatus (3) and are taken up with a draft, wherein the temperature and/or volume of the cooling air blown from the cooling apparatus is controlled so that the cooling is performed stronger, in stages or continuously, from upstream to downstream.
Patent NZ-228635-A (NZ)
Title: Preparation of 4-demethoxydaunomycinone
Inventor: CABRI WALTER
IPC: C07C45/00
Filed: 1989-04-06
Abstract: 4-Demethoxy-daunomycinone I: <CHEM> the known aglycone of 4-demethoxy-daunorubicin, is prepared by protecting the 13-keto group of 4-demethyldaunomycinone, sulfonylating the 4-hydroxy group, reacting the sulfonylated compound, in an appropriate reducing environment, with a catalytic amount of a transition metal complex, preferably palladium or nickel with 1,3 diphenylphosphinopropane or 1,1 min -bis (diphenylphosphino) ferrocene, and eliminating the 13-dioxolanyl group by treatment with trifluoroacetic acid.
Patent NZ-235976-A (NZ)
Title: Improved method for purifying superoxide dismutase from bacterial or eucaryotic cells
Inventor: BARTFELD DANIEL
IPC: C12N9/02
Filed: 1990-11-06
Abstract: Disclosed is a method of increasing the yield of recovered solutions having an increased concentration of b isoform of an enzymatically-active polypeptide analog of Cu-Zn superoxide dismutase from a composition which comprises cells containing a, b and c isoforms of the polypeptide analog comprising treating the composition to separate soluble proteins from whole cells, cellular debris and insoluble proteins to obtain a solution containing such soluble proteins, including the a, b and c isoforms; treating the resulting solution with soluble proteins to produce three separate solutions, each of which has an increased concentration of one of either of the a, b or c isoform; recovering the separate solution with an increased concentration of the b isoform; combining the separate solution with an increased concentration of the a isoform with the separate solution with an increased concentration of the c isoform; treating the resulting combined solution to produce a solution with an increased concentration of the b isoform and recovering the then-resulting solution with an increased concentration of the b isoform.
Patent NZ-236871-A (NZ)
Title: Opalescent coating compositions containing foamed metal oxides
Inventor: PANUSH SOL
IPC: C09D5/36
Filed: 1991-01-23
Abstract: Novel opalescent coatings are disclosed containing foamed metal oxides. The foamed metal oxides impart a unique opalescence to the coatings, result in more natural hues, softer colors and minimal color travel.
Patent NZ-238898-A (NZ)
Title: Multi-cell electrolyser
Inventor: MURET FREDERIC
IPC: C25B9/17
Filed: 1991-07-10
Abstract: Electrolyzer comprising at least two elementary electrolysis cells (1), coupled in electrical series along a common vertical wall (6) which comprises two vertical metal plates (10, 11), arranged on either side of a peripheral frame (12) so as to define a vertical chamber (16). One of the plates (10) carries an anode (13) of one of the cells and the other plate (11) carries a cathode (14) of the other cell. The chamber (16) contains a metal mass whose melting temperature is lower than the temperature prevailing in the said chamber when the electrolyzer is in operation. The electrolyzer is suitable for the electrolytic production of sodium chlorate.
Patent NZ-251623-A (NZ)
Title: Absorbent paper web with biodegradable softening compound and a temporary wet strength resin
Inventor: PHAN DEAN VAN
IPC: D21H/
Filed: 1993-03-29
Abstract: Tissue paper webs useful in the manufacture of soft, absorbent products such as napkins, facial tissues, and sanitary tissues, and processes for making the webs. The tissue paper webs comprise papermaking fibers, a biodegradable quaternized amine-ester softening compound, a wetting agent, and a temporary wet strength resin. The process comprises a first step of forming an aqueous papermaking furnish from the above-mentioned components. The second and third steps in the basic process are the deposition of the papermaking furnish onto a foraminous surface such as a Fourdrinier wire and removal of the water from the deposited furnish. An alternate process involves the use of the furnish containing the aforementioned components in a papermaking process which will produce a pattern densified fibrous web having a relatively high bulk field of relatively low fiber density in a patterned array of spaced zones of relatively high fiber density.
Patent NZ-253795-A (NZ)
Title: Lining for block-shaped container, and transport pack for the lining
Inventor: VAN GIEZEN MAURICE GERARDUS MA
IPC: B65D77/06
Filed: 1993-06-03
Abstract: A lining (1) for a block-shaped container, which lining is made of flexible material and can be placed folded in the container, and can then be brought to the desired shape in the container through filling. The lining is folded up or rolled up to the form of an elongated strip, which can be placed in the container in a position in which it extends with its lengthwise direction at least between the top edge and the bottom wall thereof, in such a way that during filling the lining can unfold relative to said lengthwise direction towards the two opposite sides.
Patent NZ-264650-A (NZ)
Title: Moulding liners in container closures: gas pressure on piston sets compression moulding force
Inventor: INGRAM KEITH W
IPC: B29C43/08
Filed: 1994-10-10
Abstract: A method and apparatus for compression molding closure liners wherein a set of tooling including a first assembly (35) and second assembly (36) which are movable toward and away from one another. The first assembly (35) of tooling has a liner forming member and a closure engaging sleeve thereon and the second assembly (36) has a closure supporting pad (41) thereon. A cam (37) is associated with the first assembly of tooling for moving the closure engaging sleeve into engagement with a closure and the liner forming member into position for compression molding a charge of plastic extrudate in the closure when it is supported on the closure supporting pad (41). A gas cylinder (39) is associated with the closure supporting pad providing a predetermined controlled pressure that determines the compression molding force on the plastic. In a preferred mode, a plurality of sets of tooling are provided in circumferentially spaced relation to one another on a turret. <IMAGE>
Patent NZ-265949-A (NZ)
Title: Transdermal therapeutic system; comprises an indole derivative as an active ingredient
Inventor: LIST HARALD
IPC: A61K9/70
Filed: 1994-04-25
Abstract: The invention concerns a transdermal therapeutic system for the systemic administration of active substances, the system being characterized in that at least one of the active substances is a serotonin agonist selected from the indole derivatives, e.g. sumatriptan.
Patent NZ-273652-A (NZ)
Title: Data (bar code) reading wand with user display and telecommunication facility
Inventor: CALLAGHAN FRANCIS JOHN
IPC: G06Q30/06
Filed: 1994-09-27
Abstract: A hand holdable data entry unit (10) comprising a reading sensor (14, 90) for sensing commands and/or data and for producing input signals in response to said sensed commands and/or data, rewritable storage (78) programmable with information relating to selectable items, a controller (74) connected to receive and process said input signals from said sensor (14, 90), said controller (74) being arranged to respond to commands and/or sensed commands to control said data entry unit (10) and to said data to select a said item and a display screen (20) for displaying a user readable representation of said commands and said stored information for said selected item, and a telecommunications interface (52, 94, 116) for telephonic transmission of information relating to a selected item or items from said storage (78) to a telecommunications network (50) and for telephonic reception of information relating to said selectable items to said storage (78) from said telecommunications network (50), wherein said telecommunications interface (52, 94, 116) is a telecommunications line interface integral to said data entry unit (10) and directly connects said data entry unit (10) to said telecommunications network (50). <IMAGE> <IMAGE>
Patent NZ-278079-A (NZ)
Title: Paramunity inducer comprising combinations of poxvirus components
Inventor: MAYR ANTON
IPC: C12N7/00
Filed: 1995-01-17
Abstract: Multipotent paramunity inducers are described which are based on combinations of poxvirus components derived from various poxviruses with paramunizing properties and which have been improved in terms of their potency and their paramunization-related activities as compared with the known paramunity inducers. The invention also relates to a method for preparing these multipotent paramunity inducers and to their use as drugs.
Patent NZ-282565-A (NZ)
Title: Condensed mercaptoacetylamidedisulphidebenzazepines used in treating elevated cholesterol levels, atherosclerosis, and hypotriglyceridemia
Inventor: FLYNN GARY A
IPC: C07D471/04
Filed: 1995-02-28
Abstract: Disclosed is the use of certain mercaptoacetylamide disulfide derivatives in treating patients suffering from hypertriglyceridemia, atherosclerosis and hypercholesterolemia.
Patent NZ-291704-A (NZ)
Title: Stacking tray: sheet folded around and locked to rigid end panels
Inventor: HARRELSON GLEN RAY
IPC: B65D21/02
Filed: 1995-08-15
Abstract: A container formed by wrapping a slotted flexible sheet about rigid end panels having upper corner projections that extend through the slots. The sheet is attached to the end panels by locking tabs extending from inwardly sloped portions of the side panels. By using locking tabs instead of upper panel flaps the side panels of the container may be of multi-ply construction when required by anticipated loading and shipping stresses.
Patent NZ-308395-A (NZ)
Title: Thrombopoietin compositions and method for reducing adsorption of Thrombopoietin to a surface
Inventor: SENDEROFF RICHARD I
IPC: A61K38/19
Filed: 1996-05-22
Abstract: Compositions of thrombopoietin and a method of reducing adsorption of thrombopoietin to a surface are disclosed. The compositions comprise, in addition to thrombopoietin, a physiologically acceptable buffer, a surface adsorption inhibitor selected from the group consisting of non-ionic surfactants and polyols, and an isotonic amount of a physiologically acceptable salt.
Patent NZ-329949-A (NZ)
Title: Retractable flexible cover, moves on upwardly sloping guide
Inventor: WILLIAMS PHILLIP ALAN
IPC: E04H15/58
Filed: 1998-03-11
Abstract: A guide for assisting in the closure of suspended flexible panels (2,3) comprising a mounting bracket (10) for mounting to the top of a support post (1), an arm (15), which extends upward and outward from the mounting bracket (10) at about 10º from the horizontal and a return arm (17) to form a slot (19).  In use, the moving edge (5) of the flexible panel (3) is moved towards the guide and into the slot (19) overlapping the fixed edge (4) of flexible panel (2). The guide prevents uplift of the flexible panel (3) in windy conditions.
Patent NZ-333257-A (NZ)
Title: Substituted cyclohexyl-phenyl-glycolates as spasmolytic agents
Inventor: ABERG A K GUNNAR
IPC: C07C225/18
Filed: 1997-06-30
Abstract: A compound of the formula disclosed are racemates and optically active isomers of substituted aminobutyl derivatives of cyclohexylphenylglycolic acid, including esters, amides and keto isosteres, which possess smooth muscle spasmolytic properties with reduced anticholinergic and cardiodepressive side effects. Wherein; X is oxygen, -NH or methylene; R1 and R2 are independently selected from the group consisting of hydrogen, C1-4alkyl, (CH2)2OH and (CH2)3OH with the proviso that: 1) When X is oxygen: R1 and R2 are not both CH3; R1 and R2 are not both C2H5; R1 and R2 are not both C3H7; R1 is not C2H5, when R2 is hydrogen; R1 and R2 are not both C4H9; and R1 is not CH3 when R2 is C2H5; 2) When X is -NH: R1 is not hydrogen when R2 is CH3 when said compound is in the racemic form; R1 is not hydrogen when R2 is C2H5; R1 and R2 are not both CH3; R1 and R2 are not both C2H5; R1 and R2 are not both C3H7; R1 and R2 are not both C4H9; R1 is not (CH2)2OH when R2 is hydrogen or CH3 or C2H5, when said compound is in the racemic form; and R1 is not (CH2)3OH when R2 is hydrogen or CH3 or C2H5, when said compound is in the racemic form; or 3) When X is methylene: R1 and R2 are not both hydrogen when the compound is in the racemic form or in the R-form; R1 and R2 are not both CH3, when the compound is in the racemic form or in the R-form; R1 and R2 are not both C2H5, when the compound is in the racemic form or in the R-form; R1 is not hydrogen when R2 is CH3; and R1 is not hydrogen when R2 is C2H5 when the compound is in the racemic form or in the R-form.
Patent NZ-335114-A (NZ)
Title: Diagnosis of chronic fatigue syndrome by detecting a 30 kDa RNase L molecule from peripheral blood mononuclear cells
Inventor: SUHADOLNIK ROBERT J
IPC: C12Q1/34
Filed: 1997-09-19
Abstract: Chronic fatigue syndrome is diagnosed through detection of an about 30 kDa RNase L molecule under native conditions in cellular extracts of RNase L-containing cells such as peripheral blood mononuclear cells. Proteins are fractionated according to molecular weight under non-denaturing conditions. The fractionated proteins are assayed for the presence of the about 30 kDa protein having 2-5A-dependent RNase L enzyme activity. The severity of the affliction may be determined by testing for the presence of RNase L molecules having approximate molecular weights of 30 and 80 kDa. The presence of the about 30 kDa RNase L, and the absence of the about 80 kDa RNase L molecule, correlates with severe chronic fatigue syndrome. The presence of both RNase L molecules indicates a less severe chronic fatigue syndrome affliction. Under de-naturing conditions, and in the presence of protease inhibitors, chronic fatigue syndrome may be diagnosed through the detection of an about 37 kDa 2-5A binding protein.
Patent NZ-335736-A (NZ)
Title: 3-(3-{[3-(3-chloro-phenyl)-propyl]-methanesulfonyl-amino}-propyl)-benzoic acid and similar compounds for the treatment of osteoporosis
Inventor: CAMERON KIMBERLY O'KEEFE
IPC: A61K31/4406
Filed: 1997-11-10
Abstract: Prostaglandin agonists described by the formula shown, in which, for example, A is a sulphonyl or acyl group, B is N or CH, M contains a ring and K and Q are linking groups, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits useful for the treatment of bone disorders including osteoporosis.