baber/WOPTO huggingface dataset:
Patent EA-019357-B1 (EA)
Title: Alkylsulfonyl-substituted n-(thiazole-2-yl)benzamides and use thereof for treating hepatitis c virus infection
Inventor: SEMPLE J EDWARD
IPC: A61K31/426
Filed: 2008-08-01
Abstract: A new class is proposed of alkylsulfonyl-substituted N-(thiazole-2-yl)benzamide and use thereof of general formula (I)or a salt thereof, in which R-Rare, each independently of one another, chosen from H, OH, (C-C)alkylthio, (C-C)alkylsulfonyl, -O-CO-(C-C)alkyl and -O-SO-(C-C)alkyl; and Rand Rare, each independently of one another, chosen from a group comprising H, (C-C)alkylthio, (C-C)alkylsulfonyl and -O-SO-(C-C)alkyl, provided that at least one of R-Ror Ris (C-C)alkylsulfonyl or -O-SO-(C-C)alkyl. These compounds show strong activity against hepatitis virus.
Patent EA-019091-B1 (EA)
Title: Glucocorticoid receptor agonist composed of 2,2,4-trimethyl-6-phenyl-1,2-dihydroquinoline derivative having substituted oxy group
Inventor: KATO MASATOMO
IPC: A61K31/47
Filed: 2009-05-12
Abstract: Disclosed is a glucocorticoid receptor agonist composed of a compound represented by formula (1) or a salt thereof, which is a 2,2,4-trimethyl-6-phenyl-1,2-dihydroquinoline derivative having a substituted oxy group. A novel pharmacological action of the agonist is also disclosed. In the formula, Rrepresents a group represented by formula (2a), (3a), (4a) or (5a); Rrepresents -(CO)-R, -(CO)O-Ror the like; R-O- is substituted at the 4-position or the 5-position of the benzene ring A; Rrepresents an alkyl group; R, R, Ror Rrepresents a halogen atom, an optionally substituted an alkyl group or the like; m, n, p or q represents 0, 1 or the like; and R, Ror the like represents an optionally substituted an alkyl group, an alkenyl group or the like.
Patent EA-019143-B1 (EA)
Title: Use of histamine h4 antagonist for the treatment of post-operative adhesions
Inventor: THURMOND ROBIN L
IPC: A61K39/395
Filed: 2009-06-11
Abstract: The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering a histamine H4 receptor antagonist, systemically, directly to tissue surfaces in the body cavity, or both, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.
Patent EA-020143-B1 (EA)
Title: Solid dosage form having an anorectic effect (variants)
Inventor: CHELYAEVA ANASTASIYA GENNADIEVNA
IPC: A61K9/20
Filed: 2012-10-02
Abstract: The invention relates to the pharmaceutical industry and medicine and can be used in the creation and administration of solid dosage forms for the treatment and/or prophylaxis of obesity. The present invention addresses the problem of creating an effective solid dosage form containing sibutramine hydrochloride monohydrate and having an anorectic effect. The problem of interest is solved by the inclusion of additional mineral substances in the solid dosage form and also by the use of carbon-13 and nitrogen-15 isotopes. The technical results of the invention are: a greater therapeutic effect (a reduction in body weight or a decrease in the rate of weight gain) in the treatment and/or prophylaxis of obesity with no decrease in the duration of the effect or increase in the concentration of sibutramine hydrochloride monohydrate, and a more rapid onset of said therapeutic effect.
Patent EA-025583-B1 (EA)
Title: Method for electric geophysical survey and device for implementation thereof
Inventor: GOVORKOV SERGEY IVANOVICH
IPC: G01V3/12
Filed: 2012-09-05
Abstract: The invention is related to the field of geophysics and, in particular, to search and delineation of hydrocarbon reservoirs without well drilling. The objective of the invention is higher reliability and accuracy of deposit identification. The claimed method comprises irradiation of the geological profile under study from a mobile platform with an electromagnetic wave at two fixed frequencies fand f, measurement of electric field intensities Eand Eat these frequencies at geological profile points with operating transmitters, then measurement of electric field intensities Eand Ewith transmitters disabled, determination of a differential signal E=E-Eand E=E-Efor each frequency, calculation of the ratio β=E/Efor each point of the geological profile, and determination of coordinates of the geological profile measurement points by the global positioning system. From anomalous values of parameter β and on the basis of the global positioning system data, the presence and boundaries of a deposit are judged. The number of fixed frequencies used can be more than two. The device according to the invention comprises the following units mounted on a mobile platform: transmitters (1), (3) and receivers (2), (4) forming two transceiving pairs, an interface unit (5), a navigation receiver (6), a terminal device (7), a control unit (8), and two switching devices (8) and (9). All above-mentioned receivers and transmitters are equipped with antennas that can be spatially oriented. The antennas, except for the antenna of the receiver (6), are mounted at a fixed suspension height. The input of the interface unit (5) is connected to the navigation receiver (6) and the switching device (10), and its output is connected to the terminal device (7). The transmitters (1), (3) are arranged on the platform, in respect of the receivers (2), (4), at a distance satisfying the condition: X/λ=X/λ=const, where Xand Xare distances between respective transmitters and receivers, λand λare wavelengths corresponding to radiation frequency of transmitters (1), (3). The outputs of the switching device (9) are connected to the respective inputs of transmitters (1), (3), and the outputs of the receivers (2), (4) are connected to the respective inputs of the switching device (10). The output of the control unit (8) is connected to the switching devices (9), (10), and its input is connected to the terminal device (7). The number of transceiving pairs can be more than two.
Patent EA-028408-B1 (EA)
Title: Method for creating and recognizing an anti-counterfeit identification of random texture and recognizer thereof
Inventor: SUN XIANLIN
IPC: D21H15/06
Filed: 2010-09-28
Abstract: An anti-counterfeit method for random texture and a recognizer thereof are provided by the invention. The method includes the following steps: A. texture material 2 with texture element 1 distributed randomly is selected; B. a recognition system stores inherent recognition feature J of texture element 1; C. random feature S distributed in texture 1 is extracted and stored in the recognition system, and texture 2 is enabled to be anti-counterfeit identification 3; D. in recognizing, the recognition system extracts feature J' and random feature S' of texture element 1' to be recognized on anti-counterfeit identification 3' to be recognized, and compares respectively feature J' with recognition feature J as well as random feature S' with random feature S, if one or two of the compared results does not match, anti-counterfeit identification 3' to be recognized is judged not to be anti-counterfeit identification 3, otherwise, anti-counterfeit identification 3' to be recognized is judged to be anti-counterfeit identification 3. The method can be applied to implement that the inherent feature of a texture element is not imitated and deceived by a printed texture element, and it can support a cheap and simple recognizer.
Patent EA-027700-B1 (EA)
Title: Viscosified fluid loss control agent utilizing chelates
Inventor: LUYSTER MARK
IPC: C09K8/60
Filed: 2011-09-30
Abstract: The invention relates to a well treatment method comprising the steps of injecting into a well a fluid loss control agent comprising a chelating agent, a viscosity increasing agent, and a plurality of at least partially insoluble bridging solid particles dispersed therein, wherein the chelating agent is effective to at least partially solubilize at least a portion of the bridging solid particles over a solubilizing period of time for thereafter substantially dissolving the bridging solid particles, wherein the solubilizing period of time is controlled by the concentration of the viscosity increasing agent, the concentration of the chelating agent, the composition of the metal salt, the pH of the fluid loss control agent, or a combination thereof. A fluid loss control agent is also disclosed.
Patent EA-028886-B1 (EA)
Title: CERTAIN VARIABLE DOMAINS AGAINST VEGF FUSED WITH Fc-DOMAINS
Inventor: ASHMAN CLAIRE
IPC: C07K16/22
Filed: 2012-07-25
Abstract: The present invention is directed to antigen binding constructs comprising one or two epitope binding domains separated by a single chain Fc region of an antibody, wherein each epitope binding domain in capable of binding to VEGF; to dimers comprising two antigen binding constructs of the invention; pharmaceutical compositions comprising said dimers; their use in the treatment of diseases associated with VEGF signalling, such as diabetic macular edema (DME), wet age-related macular degeneration (Wet AMD), diabetic retinopathy, retinal vein occlusion (RVO), and corneal neovascularisation; and polynucleotide sequences encoding said antigen binding constructs.
Patent EA-032501-B1 (EA)
Title: Methods and compositions for promoting acute wound and chronic wound healing
Inventor: REDDELL PAUL WARREN
IPC: A61K31/336
Filed: 2014-04-17
Abstract: The present invention relates to epoxy-tigliane compounds and their use in promoting acute wound and chronic wound healing. In particular embodiments, the epoxy-tigliane compounds are epoxy-tigliaen-3-one compounds. Methods of inducing or promoting acute wound and chronic wound healing as well as methods of reducing scarring and improving cosmetic outcomes upon healing of an acute wound and chronic wound are described. Compounds and compositions for use in acute wound and chronic wound healing are also described.
Patent EA-033771-B1 (EA)
Title: Method and device for treating organic effluents
Inventor: CAPEAU PATRICE
IPC: C02F1/20
Filed: 2014-11-27
Abstract: The invention concerns a method and a device for treating an organic effluent (2, 31). The effluent is fed in a continuous flow at a rate q (m/h), via a first chamber (5) maintained at a first specific pressure (P), and/or directly through a first narrowing (7), to a second chamber or container (10, 33, 55) maintained at a second medium specific pressure (P, P', P'', P'') by the injection of air (11, 31, 54) into said second chamber at a rate Q (Nm/h), in order to obtain an emulsion (13, 57) in the second chamber, a specific head loss is generated in the emulsion optionally modified by a second and/or third narrowing or a feed valve (61) for a third chamber (22, 39, 62) maintained at a third specific pressure (P, P', P'') in the region (79) immediately downstream of the second or third narrowing and/or valve (61), and a flocculant (24, 45, 78) is injected into the region of the third chamber, the emulsion at atmospheric pressure then being degasified and the emulsion thus degasified being recovered in a filtration or decanting device.
Patent EA-033138-B1 (EA)
Title: Goa circuit for liquid crystal display device
Inventor: XIAO JUNCHENG
IPC: G09G3/36
Filed: 2015-01-08
Abstract: Disclosed is a Gate Driver On Array (GOA) circuit for a liquid crystal display device. The liquid crystal display device comprises a plurality of scanning lines. The GOA circuit comprises a plurality of cascaded shift register units. An Nth-level shift register unit controls charging of an Nth-level scanning line (G(N)). The Nth-level shift register unit comprises a forward and reverse scanning control circuit, a pull-up circuit, a bootstrap capacitor circuit, a gate signal point electric leakage prevention circuit and a pull-down holding circuit. The bootstrap capacitor circuit, the gate signal point electric leakage prevention circuit and the pull-down holding circuit are connected together to form a gate signal point so as to improve the stability of the gate signal point and reduce the use of switches.
Patent EA-038216-B1 (EA)
Title: Method of strengthening oxidatively-treated hair
Inventor: PAUL PREM KUMAR CHEYALAZHAGAN
IPC: A61Q5/00
Filed: 2018-02-05
Abstract: The invention provides a method of strengthening the fibres of oxidatively-treated hair, the method comprising the sequential steps of: (i) washing the oxidatively-treated hair; (ii) soaking the washed hair in an aqueous treatment composition; and (iii) drying the soaked hair; characterised in that the aqueous treatment composition comprises at least 1 wt.% N-acetyl glycine (based on the total weight of the composition). The invention also provides the use of an aqueous treatment composition comprising at least 1 wt.% N-acetyl glycine (based on the total weight of the composition), for the enhanced strengthening of oxidatively-treated hair fibres relative to virgin hair fibres.
Patent EA-038752-B1 (EA)
Title: Grinding mill, pulp lifter and outer pulp lifter element
Inventor: HEATH ALEX
Filed: 2017-03-20
Abstract: An outer pulp lifter element (1) for a pulp lifter (2) for a rotating drum grinding mill (3) comprises a first wall (4) directed towards the discharge end of the grinding mill, and at least one vane (6) protruding from the inner surface (12) of the first wall (4) towards the inside of the drum grinding mill (3) and comprising a guiding surface (10) on the front side of the vane (6). The outer edge (11) of the guiding surface (10) is angled in relation to the inner surface (12) of the first wall (4) in such a manner, that the angle () between the inner surface (12) of the first wall (4) and the outer edge (11) of the guiding surface (10) is smaller than 90.
Patent ES-2187334-B1 (ES)
Title: Nuevos derivados de la hidrazida, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
Inventor: MONGE VEGA ANTONIO
IPC: A61P3/04
Filed: 2001-01-17
Granted: 2004-09-16
Abstract: Nuevos derivados de la hidrazida, su procedimiento de preparación y las composiciones farmacéuticas que los contienen Compuestos de fórmula (I): R-NH-A-CO-NH-NH-(W){sub,n }-Z en la cual: - n equivale a 0 ó a 1, - W representa un grupo -CO- o un grupo S(O){sub,r} en el cual r equivale a 0, 1 ó 2, - Z representa un grupo seleccionado entre arilo, arilalquilo, heteroarilo heteroarilalquilo eventualmente sustituidos, y alquilo, - R representa un grupo seleccionado entre: Z{sub,1}-T-CO-,Z{sub,1}- O-T-CO-,Z{sub,1}-T-O-CO-,Z{sub,1}-T-S(O){sub,q}- en los cuales Z{sub,1}, T y q son tales como se han definido en la descripción, - A representa un grupo alquileno, alquenileno o alquinileno de 3 a 8 átomos de carbono, alquilencicloalquilenalquileno, alquilenarileno, arilenalquileno, alquilenarilenalquileno, un grupo **FIGURA-01** en el cual B{sub,1} es tal como se ha definido en la descripción, o bien A forma con el átomo de nitrógeno adyacente un grupo **FIGURA- 02** tal como se ha definido en la descripción. Medicamentos.
Patent ES-2196998-B1 (ES)
Title: Procedimiento para medir el umbral anaerobico.
Inventor: MU-CHUAN WU
IPC: A61B5/22
Filed: 2002-02-27
Granted: 2005-06-01
Abstract: Procedimiento para medir el umbral anaeróbico (UA) incluye una pluralidad de etapas llevadas a cabo por una unidad de introducción de datos, una unidad de selección de la clase de carga, una unidad de detección y de cálculo y una unidad de visualización. Las etapas incluyen introducir la edad, peso y sexo del usuario que lleva un emisor de la frecuencia cardiaca y que usa un aparato de ejercicio (por ejemplo un tapiz rodante) dotado de dichas unidades, y seleccionar una clase de carga para hacer ejercicio en el aparato de ejercicio. A continuación, las unidades detectan, miden y registran el ciclo de frecuencia cardiaca y calculan la diferencia de frecuencia cardiaca entre ciclos detectada para un período determinado de tiempo. A continuación, se calcula el punto límite del UA y se presenta en la unidad de visualización para que el usuario tenga una referencia con el fin de controlar la carga de ejercicio y el tiempo.
Patent ES-2223246-B1 (ES)
Title: Expositor de paneles abatibles.
Inventor: PEREZ ESTEBAN JOSE
IPC: A47F5/00
Filed: 2002-11-22
Granted: 2006-03-16
Abstract: Expositor de paneles abatibles, constituido por una estructura modular que está compuesta por al menos un módulo portapaneles (16) y al menos un módulo de armado (17). Los módulos portapaneles consisten en una armadura quebrada, formada a partir de un marco de bases paralelas con dos quiebros simétricos perpendiculares hacia sus bases, dirigidos hacia un mismo lado y de amplitud igual o mayor de 90°, que determinan en cada base tramos centrales que son portadores de medios (9 y 10) de articulación entre los que se montarán paneles portadores de las piezas cerámicas. El módulo de armado (7) consiste en un bastidor que se fija a los lados superior e inferior del módulo o módulos portapaneles (16).
Patent ES-2249091-B1 (ES)
Title: Recuperador de energia, generada por la circulacion de liquidos a presion a traves de una tuberia.
Inventor: TOMAS MASSOT ALEJANDRO
IPC: F03B17/06
Filed: 2003-07-04
Granted: 2007-05-01
Abstract: Recuperador de energía, generada por la circulación de líquidos a presión a través de una tubería. Objeto de la invención: la presente memoria descriptiva se refiere a una solicitud de Patente de Invención, relativa a un recuperador de energía, basado en que el líquido que circula por una tubería (de las existentes para la conducción de agua o similar) el cual ejerce una presión sobre una hélice con palas de tipo cuchara, produce una fuerza motriz que se puede recuperar mediante el correspondiente mecanismo. La invención, al ser totalmente autónoma no precisa de energía convencional o alternativa adicional y solo precisa de ser instalada en las conducciones urbanas o alternativas de agua alimentadas por depósito (alimentación por gravedad o presión), al ser constante la presión, la rotación de la hélice, no produce merma alguna en la circulación del agua canalizada. Campo de la invención: esta invención tiene su aplicación dentro del campo de las energías alternativas, para su aplicación enla industria de la construcción, distribución de agua canalizada y actividades comerciales, industriales y similares. Antecedentes de la invención: por parte del solicitante no se tiene conocimiento de la existencia en la actualidad de una invención que contemple una recuperador de energía generada por la circulación de líquidos a presión o canalizados por tubería.
Patent ES-2257158-B1 (ES)
Title: Procedimiento para la produccion y purificacion de somatostatina en celulas de escherichia coli a partir de la expresion en las mismas del gen codificante clonado en el vector pgrv1.
Inventor: VICENTE GARCIA PABLO
IPC: C12N15/70
Filed: 2004-07-09
Granted: 2007-08-01
Abstract: Procedimiento para la producción y purificación de somatostatina en células de Escherichia coli a partir de la expresión en las mismas del gen codificante clonado en el vector pGRV1. Mediante técnicas básicas de ingeniería genética se ha clonado el extremo N-terminal de la beta-galactosidasa de Kluyveromyces lactis en el plásmido comercial pET17xb, generando dos sitios de restricción únicos susceptibles de ser utilizados para la clonación de secuencias codificantes de péptidos, dando lugar al plásmido pGRV1. La secuencia codificante de la hormona somatostatina se ha obtenido mediante una amplificación en cadena de la polimerasa (PCR) utilizando oligonucleótidos solapantes, clonando posteriormente el gen en el plásmido pGRV1, para dar lugar al plásmido pSOMA. La cepa de Escherichia coli BL21 (DE3) se transformó con el plásmido pSOMA dando lugar a la cepa CECT5840. Utilizando equipos de fermentación convencional se han obtenido cantidades suficientes de proteína de fusión, que tras su digestión con bromuro de cianógeno se han purificado cromatográficamente. El péptido obtenido muestra propiedades cromatográficas coincidentes con las de un patrón comercial.
Patent ES-2257190-B1 (ES)
Title: Electrocatalizador anodico para pilas de combustible de membrana de intercambio de protones alimentadas con metanol.
Inventor: MARTINEZ HUERTA MARIA VICTORIA
IPC: B01J37/00
Filed: 2004-10-26
Granted: 2007-07-01
Abstract: Electrocatalizador anódico para pilas de combustible de membrana de intercambio de protones alimentadas con metanol. Electrocatalizador para su uso en el ánodo de una pila de combustible de membrana de intercambio de protones alimentada directamente por metanol (DMFC), y procedimiento para la obtención de dicho electrocatalizador. El electrocatalizador está compuesto por una fase metálica Pt-Ru soportada sobre un negro de humo cuya superficie se ha modificado previamente. La modificación del negro de humo se lleva a cabo tratándolo con distintos agentes oxidantes, produciendo un aumento del número de grupos funcionales superficiales. Posteriormente se incorpora la fase activa (platino-rutenio) a la superficie del soporte que se ha modificado mediante cualquiera de los diferentes métodos conocidos en el estado de la técnica. El electrocatalizador resultante mejora el comportamiento electrocatalítico para la oxidación de metanol con respecto a otros electrocatalizadores conocidos en el estadode la técnica y cuyo soporte carbonoso no se ha tratado para obtener grupos funcionales superficiales.
Patent ES-2257950-B1 (ES)
Title: Procedimiento para la preparacion de oximas catalizado por un material laminar deslaminado.
Inventor: IBORRA CHORNET SARA
IPC: B01J29/06
Filed: 2004-12-01
Granted: 2007-07-16
Abstract: Procedimiento para la preparación de oximas catalizado por un material laminar deslaminado. Procedimiento para la preparación de oxima de una cetona con un número de átomos de carbono superior a 10, caracterizado porque comprende poner en contacto dicha cetona que tiene más de 10 átomos de carbono, con amoniaco y peróxido de hidrógeno en presencia de un material laminar deslaminado que contiene Ti, como catalizador.
Patent ES-2284305-B1 (ES)
Title: Mejoras introducidas a la patente de invencion n. p-9800924/9, por: sistema de recogida y extendido de lonas para cubricion de cajas de vehiculos.
Inventor: MORGA ROS JOSE
IPC: B60J7/06
Filed: 2005-02-16
Granted: 2008-09-16
Abstract: Mejoras introducidas a la Patente de Invención n° P-9800924/9, por: sistema de recogida y extendido de lonas para cubrición de cajas de vehículos. Las mejoras consisten en un dispositivo para plegar y desplegar la lona de la caja de un camión, lona que tiene la función de cubrir la parte superior de la caja para proteger los productos ubicados en su interior, esencialmente durante el transporte. El dispositivo comprende básicamente dos cadenas longitudinales (15) dispuestas superiormente a ambos lados de la caja (5) y las cuales se acoplan en unos piñones extremos (13 y 14), a la vez que la lona (1) posee unos arquillos transversales (2 y 3) vinculados al ramal superior de esas dos cadenas (15), de manera que el giro de esos piñones (13 y 14) mueve la cadena (15) y éstos a su vez mueven la lona para su plegado y desplegado, por mediación del último arquillo (3) solidarizado a las cadenas longitudinales (15).
Patent ES-2263373-B1 (ES)
Title: Armario de desarrugado y secado de ropa.
Inventor: AIZPURU BORDA AITOR
IPC: D06F34/26
Filed: 2005-03-23
Granted: 2007-12-01
Abstract: Armario de desarrugado y secado de ropa que comprende un recinto (2) cerrado y estático que define una zona interior (3) para albergar ropa, un generador de flujo de aire (4) para hacer circular aire a través de dicha zona interior (3), medios de calentamiento (5) para calentar dicho flujo de aire, y medios (6) de condensación o de evacuación para condensar el agua del aire que circula a través de la zona interior (3) o para evacuar el aire respectivamente, accediendo el flujo de aire a la entrada (61) de dichos medios (6) tras atravesar dicho flujo de aire dicha zona interior (3) y estando dichos medios (6) dispuestos verticalmente. El armario comprende un sensor (7) de temperatura y humedad dispuesto a la entrada (61) de los medios (6) de condensación o de evacuación.