baber/WOPTO huggingface dataset:
Patent EP-2267132-A2 (EP)
Inventor: CHOPPIN JEANNINE
IPC: C12N15/37
Filed: 2000-05-31
Abstract: Polyepitopic fragments (I) from the human p53 that is overexpressed in many types of cancers, are new. Polyepitopic fragments (I) from the human p53 that is overexpressed in many types of cancers, are new. (I) is contained within any of the sequences ThrTyrGlnGlySerTyrGlyPheArgLeuGlyPheLeuHisSerGlyThrAlaLysSerVal- ThrCysThrTyrSerProAlaLeuAsnLysMetPheCysGlnLeu; SerThrProProProGlyThrArgValArgAlaMetAlaIleTyrLysGlnSerGlnHisMet; GlyLeuAlaProProGlnHisLeuIleArgValGluGlyAsnLeuArgValGluTyrLeuAsp- AspArgAsnThrPheArgHisSerValValValProTyr; GlySerAspCysThrThrIleHisTyrAsnTyrMetCysAsnSerSerCysMet; ArgProIleLeuThrIleIleThrLeuGluAspSerSerGlyAsnLeuLeuGlyArgAsnSer- PheGluValArg. These represent, respectively, amino acids 102-137, 149-169, 187-212, 226-243 or 249-273 of p53, and bind stably to, respectively, the human leukocyte antigen (HLA) type molecules A2, A24 or B62; A2, A3, A24, B27, B35, or B62; A2, A24, B27 or B44; A1, A24 or B44; or A2, B27, B35, B44 or B62. Alternatively, (I) may be a derivative of the sequences, binding to the same HLA molecules as the parent compounds, formed by substitution, deletion and/or addition of one or more amino acids, modification of at least one peptide bond (particularly replacement by retro or retro-inverso bonds) and/or substitution of at least one amino acid by a non-proteinogenic amino acid. Independent claims are also included for the following: (1) nucleic acid (II) that encodes (I) or its derivatives; (2) mono- or poly-clonal antibodies (Ab) directed against (I) or its derivatives; and (3) pharmaceutical composition or vaccine containing at least one (I), or its derivative, (II) or Ab. - ACTIVITY : Cytostatic. No biological data is given. - MECHANISM OF ACTION : (I) induces a specific immune response; they induce cytolysis, by cytotoxic T cells (CTL), of cells that express (I) associated with appropriate HLA molecules and induce secretion of cytokines (particularly interleukins -2 and -4, and gamma -interferon) by these CTL; vaccine
Patent EP-2278012-A2 (EP)
Inventor: KINNEY RICHARD M
IPC: A61K39/12
Filed: 2001-02-16
Abstract: Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural genes of the virus are used as a backbone into which the structural protein genes of a second flavivirus strain are inserted. These chimeric viruses elicit pronounced immunogenicity yet lack the accompanying clinical symptoms of viral disease. The attenuated chimeric viruses are effective as immunogens or vaccines and may be combined in a pharmaceutical composition to confer simultaneous immunity against several strains of pathogenic flaviviruses.
Patent EP-2275118-A2 (EP)
Inventor: DOHRMANN CORD
IPC: A61K45/00
Filed: 2003-05-30
Abstract: The present invention discloses polynucleotides which identify and encode DP119, DP444, DP810, DP685, WE474, DP160, RA977, or RA770 as well as novel functions for these proteins of the inventions. The invention provides for compositions for disorders associated with the expression of the proteins of the invention, such as for the treatment, alleviation and/or prevention of pancreatic dysfunction (for example diabetes, hyperglycemia, and impaired glucose tolerance), and related disorders, and other diseases and disorders.
Patent EP-2272362-A2 (EP)
Inventor: FEUCHT DIETER
IPC: B60K17/16
Filed: 2002-09-10
Abstract: Composition contains an active agent combination of at least one 1-(thienyl-3-yl-sulfonylamino-(thio)carbonyl)-1,2,4-triazoline-5-(4H)-(thi)one derivative (I) (A), at least one other specific herbicides (B) and optionally a safener (C). Composition contains an active agent combination of at least one 1-(thienyl-3-yl-sulfonylamino-(thio)carbonyl)-1,2,4-triazoline-5-(4H)-(thi)one derivative if formula (I) (A), at least one other specific herbicides (B) and optionally a safener (C). [Image] Q 1, Q 2O or S; R 1alkyl (optionally substituted (os) by CN, halo or OT); alkenyl or alkynyl (both os by CN or halo); cycloalkyl or cycloalkyl-(1-4C) alkyl (both os by CN, halo or T); aryl or aryl-(1-4C) alkyl (both os by NO 2, CN, halo, T or OT); or Het or Het-(1-4C) alkyl (both os by CN, halo or T); T : 1-4C alkyl; Het : heterocyclyl containing up to 6C plus 1-4 N and/or 1 or 2 O or S; R 2H, CN, NO 2 or halo; alkyl, alkoxy, alkoxycarbonyl, alkylthio, alkylsulfinyl or alkylsulfonyl (all os by CN, halo or OT); or alkenyl, alkynyl, alkenyloxy or alkynyloxy (all os by CN or halo); R 3H, OH, SH, NH 2, CN or halo; alkyl (os by F, Cl, Br, CN, OT, COT or COOT); alkenyl or alkynyl (both os by F, Cl and/or Br); alkoxy, alkylthio, alkylamino or alkylcarbonylamino (all os by F, Cl, CN, OT or COOT); 3-6C alkenyloxy, 3-6C alkynyloxy, 3-6C alkenyloxy, 3-6C alkynyloxy, 3-6C alkenylamino or 3-6C alkynylamino; NT 2; aziridino, pyrrolidino, piperidino or morpholino (all os by Me and/or Et); cycloalkyl, cycloalkenyl, cycloalkoxy, cycloalkylthio, cycloalkylamino, cycloalkyl-(1-4C) alkyl, cycloalkyl-(1-4C) alkoxy, cycloalkyl-(1-4C) alkylthio or cycloalkyl-(1-4C) alkylamino (all os by F, Cl, Br, CN and/or T); or aryl, aryl-(1-4C) alkyl, aryloxy, aryl-(1-4C) alkoxy, arylthio, aryl-(1-4C) alkylthio, arylamino or aryl-(1-4C) alkylamino (all os by F, Cl, Br, CN, NO 2, T, CF 3, OT and/or COOT); R 4H, OH, NH 2, CN or 2-10C alkylideneamino; alkyl (os by F, Cl, Br, CN, OT, COT or COOT); alkenyl or alkynyl (both os by F, Cl and/or Br); alkoxy, alkylamino or alkylcarbonylamino (all os by F, Cl, Br, CN, OT or COOT); 3-6C alkenyloxy; NT 2; cycloalkyl, cycloalkylamino or cycloalkyl-(1-4C) alkyl (all os by F, Cl, Br, CN and/or T); or aryl or aryl-(1-4C) alkyl (both os by F, Cl, Br, CN, NO 2, T, CF 3 and/or OT); or R 3 + R 4optionally branched 3-6C alkanediyl; unless specified otherwise alkyl moieties have 1-6C, alkenyl or alkynyl moieties 2-6C, cycloalkyl or cycloalkenyl moieties 3-6C and aryl moieties 6-10C. ACTIVITY : Herbicide; Defoliant. In post-emergence tests against Chenopodium album, the herbicidal rating was 70% for 8 g/ha of 1-(4-methoxycarbonyl-2-methyl-thienyl-3-yl-sulfonylaminocarbonyl)-3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazole (Ia), 80% for 250 g/ha of bromoxynil (B') and 100% (compared with a predicted value of 94%) for a combination of 8 g/ha of (Ia) and 250 g/ha of (B'). MECHANISM OF ACTION : None given.
Patent EP-2323414-A2 (EP)
Inventor: OHTA KEIZO
IPC: H04N13/00
Filed: 2010-10-19
Abstract: A right virtual camera (302) and a left virtual camera (304) are set on a straight line passing through a reference virtual camera (300) and extending perpendicular to a camera direction of the reference virtual camera, in accordance with the reference virtual camera set within a virtual space. A right background image and a left background image are generated such that the right background image and the left background image have relative relation in accordance with positional relation between the right virtual camera (302) and the left virtual camera (304).
Patent EP-2322535-A2 (EP)
Inventor: BREAKER RONALD
IPC: C12N15/115
Filed: 2003-09-22
Abstract: It has been discovered that certain natural mRNAs serve as metabolite-sensitive genetic switches wherein the RNA directly binds a small organic molecule. This binding process changes the conformation of the mRNA, which causes a change in gene expression by a variety of different mechanisms. Modified versions of these natural "riboswitches" (created by using various nucleic acid engineering strategies) can be employed as designer genetic switches that are controlled by specific effector compounds. Such effector compounds that activate a riboswitch are referred to herein as trigger molecules. The natural switches are targets for antibiotics and other small molecule therapies. In addition, the architecture of riboswitches allows actual pieces of the natural switches to be used to construct new nonimmunogenic genetic control elements, for example the aptamer (molecular recognition) domain can be swapped with other non-natural aptamers (or otherwise modified) such that the new recognition domain causes genetic modulation with user-defined effector compounds. The changed switches become part of a therapy regimen-turning on, or off, or regulating protein synthesis. Newly constructed genetic regulation networks can be applied in such areas as living biosensors, metabolic engineering of organisms, and in advanced forms of gene therapy treatments.
Patent EP-2327345-A2 (EP)
Inventor: TOMS MATHEW JASON
IPC: A47K3/30
Filed: 2010-10-22
Abstract: A shower screen assembly floor to ceiling support pole (16) is provided. The pole is fixable to one or more shower screen panels (12, 18) so as to form an integral part of a screen assembly. The pole comprises two or more elongate pole sections (26, 28, 30) which are longitudinally telescopic to allow adjustment of the length of the pole.
Patent EP-2367062-A2 (EP)
Inventor: YAMADA TAKATSUGU
IPC: G03G15/00
Filed: 2010-11-18
Abstract: A user interface is configured to receive a user instruction when a user sets a print condition for a printer. At least one setting item including a plurality of set contents is set for the print condition. An obtaining unit obtains a status of the printer. Each of the plurality of set contents is a suitable set content suitable for the status of the printer or an unsuitable set content suitable for the status of the printer. A determination unit determines whether a set content set for the one setting item is the suitable set content or the unsuitable set content based on the status of the printer. A control unit executes at least one of a process for restricting the set content, which is determined as the unsuitable set content by the determination unit, from being used for a printing operation and a process for allowing a user to distinguish the set content, which is determined as the unsuitable setting, from another set content in the plurality of set contents which is determined as the suitable set content in the user interface.
Patent EP-2387325-A2 (EP)
Title: Procédés d'amélioration de la fonction hépatique et immunitaire chez un animal
Inventor: ZICKER STEVEN C
IPC: A23P30/40
Filed: 2010-01-14
Abstract: La présente invention concerne des compositions et des procédés d'amélioration de la santé animale et dans certains modes de réalisation des compositions et des procédés d'amélioration de la fonction hépatique et de la fonction immunitaire chez les félins âgés.
Patent EP-2448563-A2 (EP)
Title: Formulations de comprimé de 3- cyanoquinoline et leurs utilisations
Inventor: KAUL GOLDI
IPC: A61K31/4709
Filed: 2010-06-30
Abstract: Linvention concerne des compositions solides comprenant un 3-cyanoquinoline, SKI-606, ainsi quune croscarmellose sodique, un Tween, ou les deux.
Patent EP-2400980-A2 (EP)
Title: Agents thérapeutiques de visfatine pour traiter l'acné et d'autres conditions
Inventor: TENNENBAUM TAMAR
IPC: A61P17/00
Filed: 2010-01-06
Abstract: La présente invention porte sur des compositions et sur des procédés destinés à traiter l'acné et d'autres conditions. Lesdits compositions et procédés sont, en particulier, utiles pour le traitement des conditions associées au sébum.
Patent EP-2486424-A2 (EP)
Title: Eléments de conversion de rayonnement avec réflecteurs pour appareil d'imagerie radiologique
Inventor: COOKE STEVEN E
IPC: G01T1/20
Filed: 2010-09-16
Abstract: L'invention concerne un appareil comprenant une pluralité d'éléments de conversion de rayonnement (32) qui convertissent le rayonnement en lumière, et la couche réfléchissante (34) disposée autour de la pluralité d'éléments de conversion de rayonnement. La pluralité d'éléments de conversion de rayonnement peut consister en deux éléments de conversion de rayonnement et la couche réfléchissante est enveloppée autour des deux éléments de conversion de rayonnement avec des extrémités (40, 42) de la couche réfléchissante repliées entre les deux éléments de conversion de rayonnement. La couche réfléchissante (34) peut comprendre une couche de réfléchissement de la lumière (50) ayant un facteur de réflexion supérieur à 90 %, disposée adjacente aux éléments de conversion de rayonnement lorsque la couche réfléchissante (34) est disposée autour de la pluralité d'éléments de conversion de rayonnement, et une couche de barrage de la lumière (52).
Patent EP-2437679-A2 (EP)
Title: Structure de support pour prothèse
Inventor: MERCELIS PETER
IPC: A61C8/00
Filed: 2010-06-02
Abstract: L'invention concerne une structure de support destinée à une prothèse dentaire, ainsi qu'un procédé de production de cette structure de support. La structure de support (6) comprend des moyens (7) à fixer sur au moins un implant (4) et/ou au moins une dent de la mâchoire d'un patient, la structure de support (6) ayant une surface nominale (9) présentant une texture (8) qui est au moins constituée partiellement d'éléments de rétention (12). Ces éléments de rétention (12) comportent des parties saillantes et/ou des creux en relation avec la surface nominale (9) et présentant chacun une partie en retrait (13).
Patent EP-2516605-A2 (EP)
Title: Multifunktionelle kälteadditive für mitteldestillate mit verbesserter fliessfähigkeit
Inventor: KRULL MATTHIAS
IPC: C10L1/16
Filed: 2010-12-07
Abstract: Gegenstand der Erfindung sind Kälteadditive für Mitteldestillate, enthaltend A) mindestens einen Polyester der Formel (A1), worin einer der Reste R 1  bis R 4  für einen linearen C 16 -C 40 -Alkyl- oder Alkenylrest und die übrigen der Reste R 1  bis R 4  unabhängig voneinander für Wasserstoff oder einen Alkylrest mit 1 bis 3 C-Atomen, R 5  für eine C-C-Bindung oder einen Alkylenrest mit 1 bis 6 C-Atomen, R 16  für eine Kohlenwasserstoffgruppe mit 2 bis 10 Kohlenstoffatomen, n für eine Zahl von 1 bis 100, m für eine Zahl von 3 bis 250, p für 0 oder 1, und q für 0 oder 1 stehen, B) mindestens ein Copolymer aus Ethylen und mindestens einem ethylenisch ungesättigten Ester, wobei das Copolymer eine bei 140 °C gemessene Schmelzviskosität von höchstens 5.000 mPas besitzt und C) mindestens ein organisches Lösemittel.
Patent EP-2460286-A2 (EP)
Inventor: MUN CHEOL
IPC: H04B7/02
Filed: 2010-07-22
Abstract: A channel condition information feedback method and apparatus are provided for a collaborative wireless communication network using a multiple input multiple output antenna system. The apparatus includes a downlink channel estimator that estimates channels of adjacent base stations, groups base stations from among the adjacent base stations that are capable of collaborative communication, and obtains a maximum singular vector to base stations belonged to a same group; and a vector selector which selects a weight vector most accurately representing the maximum singular vector and a complex variable most accurately representing the maximum singular vector in combination with the weight vector.
Patent EP-2459176-A2 (EP)
Title: Procédé de cristallisation et biodisponibilité
Inventor: HANNA MAZEN
IPC: A61K9/22
Filed: 2010-07-30
Abstract: Cette invention concerne la préparation et la caractérisation in vitro et in vivo de nouvelles formes d'acide (1-hydroxy-2-imidazol-l-yl-l-phosphono- éthyl)phosphonique, destinées à être utilisées dans des compositions pharmaceutiques pour systèmes de délivrance de médicaments chez l'homme.
Patent EP-2504752-A2 (EP)
Title: Utilitaire d'accès rapide
Inventor: FISH NATHAN J
IPC: G06F3/048
Filed: 2010-10-26
Abstract: Les utilisateurs sont autorisés à effectuer des tâches telles que de création d'un nouveau contenu, de recherche d'éléments, de communication avec d'autres utilisateurs par l'intermédiaire d'une interface d'accès simplifiée, en définissant simultanément un emplacement pour l'interface d'accès. Un utilisateur peut commencer par taper à n'importe quel emplacement sur une toile. Le système classe les résultats possibles, en suggérant l'un d'eux en tant que meilleure correspondance, l'utilisateur pouvant passer outre à ce choix, sur quoi l'action résultante est affichée au point où l'entrée était initialement placée. L'utilisateur peut avoir pour options d'effectuer une sélection parmi les tâches disponibles et les tâches peuvent être effectuées sans sélectionner une application.
Patent EP-2520449-A2 (EP)
Inventor: PARK KI YOUNG
IPC: B60H1/30
Filed: 2010-12-27
Abstract: In a vehicle air vent according to the present invention, a plurality of vanes is installed in an air discharge port in a body so as to be rotatable in a horizontal direction. By coupling the vanes to each other, when a knob provided on one vane is operated, all of the vanes are rotated together, and a hinge shaft provided at each of an upper end and a lower end of each vane is inserted into and connected to a hinge hole of a spacer provided at each of an upper end and a lower end of the air discharge port of the air vent body. A damper bushing connected to a front end of the vane hinge shaft passing through the hinge hole is installed below the hinge hole of each spacer, to which each hinge shaft of the vane provided with the knob is connected. The vane operating feeling can be improved via a damper bushing connected to the vane hinge shaft, shock noises and operational noises to external loads can be reduced, and a deviation of the operating force, which is caused by temperature change, is not generated. Moreover, a uniform operating force can be ensured, and even during long-term use, the vane operating force does not change. Since the operating force can be adjusted by adjusting the hardness of the damper bushing, even when a mold is not modified, the vane operating force can be managed, the frictional durability of the hinge connection site can be improved, and the operational reliability can be ensured.
Patent EP-2371665-A2 (EP)
Inventor: CHADWICK SIMON
IPC: B61L23/04
Filed: 2011-03-16
Abstract: A condition monitoring system for a railway comprises a sensor for producing condition monitoring data relating to the operation of equipment; consolidation means for processing the data produced by the sensor to produce a consolidated data set which comprises a plurality of discrete values which relate to the condition monitoring data; and output means for outputting the consolidated data set.
Patent EP-2375002-A2 (EP)
Title: Abradable seal for a gas turbine engine, corresponding gas turbine engine and manufacturing method
Inventor: STROCK CHRISTOPHER W
IPC: F01D11/12
Filed: 2011-03-29
Abstract: An abradable seal (36) for a gas turbine engine includes a metal alloy and a plurality of pores in the metal alloy. The plurality of pores have a diameter of approximately 1 to 10 microns.
Patent EP-2383239-A2 (EP)
Inventor: EMORI IKUKO
IPC: C04B35/19
Filed: 2011-04-28
Abstract: The present invention provides a porous body having a pH adjusting function. This porous body can be obtained by a method including the steps of: preparing a mixture including a glass powder A containing an alkali component, a powder B including at least one crystal selected from a) a clay mineral that has a layered crystal structure and b) a zeolite, and a powder C of a water-soluble inorganic salt, the mixture containing 0.05 to 3 parts by mass of the powder B and 0.2 to 4 parts by mass of the powder C with respect to 1 part by mass of the glass powder A; forming the mixture into a shaped body; firing the shaped body at a temperature lower than a melting point of the water-soluble inorganic salt and equal to or higher than a softening point of the glass contained in the glass powder A to obtain a fired body; and leaching the water-soluble inorganic salt from the fired body to obtain a granular porous body. The main component of the powder B is at least one crystal selected from a 1:1 type mineral, a 2:1 type mineral other than a smectite mineral, a mixed-layer type mineral, a 2:1 ribbon type mineral, and a zeolite.
Patent EP-2410392-A2 (EP)
Inventor: NOETZELMANN OSWIN
IPC: G06F9/44
Filed: 2011-06-14
Abstract: A visual representation of a mechanical-electrical machine behavior model is presented that utilizes a non-linear time scale to best illustrate multiple details occurring in a relatively short time frame without affecting the amount of information contained in the complete model. In particular, time periods (T 1 ,T 3 ,T 6 ) without user-relevant details are identified and minimized so as to allow for the display space to adequately represent the details associated with the actions of each machine. By "folding" these longer time periods to occupy relatively short lengths along the time axis, additional space along the time axis is then available to illustrate the details of each operation (i.e., by using a non-linear time scale).
Patent EP-2422704-A2 (EP)
Inventor: YOO JAE HEUNG
IPC: G01S15/89
Filed: 2011-07-22
Abstract: Embodiments for providing ultrasound spatial compound images are disclosed. In one embodiment, by way of non-limiting example, an ultrasound system comprises: an ultrasound data acquisition unit configured to acquire ultrasound data for a periodically moving target object; and a processing unit in communication with the ultrasound data acquisition unit, the processing unit being configured to form a plurality of ultrasound images based on the ultrasound data, detect moving periods of the target object based on the ultrasound images, reconstruct the ultrasound images corresponding to each of the moving periods and perform spatial compounding upon the reconstructed ultrasound images to form ultrasound spatial compound images.
Patent EP-2518401-A2 (EP)
Inventor: TSENG SHIH-CHE
IPC: F21V29/00
Filed: 2011-08-30
Abstract: A heat dissipating device includes a tubular body (2) having a first open end (211), and a plurality of heat dissipating fins (3), each having a fin body (31) and a first engaging portion (32) formed on the fin body (31) for engaging the first open end (211) of the tubular body (2) in a manner that the heat dissipating fins (3) are disposed to radiate from and to surround the tubular body (2). The first engaging portion (32) includes a first extension section (321) bent from the fin body (31), and a first hook (322) extending from the first extension section (321) for hooking onto the tubular body (2) at the first open end (211).
Patent EP-2436932-A2 (EP)
Inventor: BOSBACH FRANZ
IPC: H01F1/44
Filed: 2011-09-30
Abstract: The sealing apparatus comprises a bearing housing (5) and a rotating shaft (2) which relatively move between two areas of different pressure or medium, within the region (8) of the gap (6). A magnet assembly (7) generates a magnetic field which counteracts with the shift of the fluid (9) which is partially composed of ionic liquid and magnetic components. A portion of the ionic-magnetic fluid components is composed of anions and cations.
Patent EP-2453169-A2 (EP)
Inventor: KOTRO JORMA
IPC: F21V21/04
Filed: 2011-11-01
Abstract: The invention relates to a recessed light fitting (1) which comprises a frame (2) for receiving one or more light sources. In order to provide a light fitting that is simply and flexibly installable in various installations the light fitting (1) comprises, in addition to the frame (2), a connection device box (7) through which power supply is arranged to said one or more light sources in the frame (2), and to adapt the appearance of the light fitting (1) to meet the requirements of the installation the connection device box (7) and the frame (2) may be mutually arranged in alternative positions.