baber/WOPTO huggingface dataset:
Patent CA-2365118-A1 (CA)
Title: Inhibitor against human chymase activity
Inventor: MIZUNO TSUYOSHI
IPC: A61P29/00
Filed: 2001-01-17
Abstract: Benzimidazole derivatives of the general formula (1) or medically acceptable  salts thereof, and human chymase inhibitors containing the derivatives or th e salts as the active ingredient: wherein ring A is a pyridine ring or a benze ne ring; X?1~ and X?2~ are each hydrogen, halogeno, trihalomethyl, cyano, optionally substituted alkyl, optionally substituted alkoxy, or the like; B is optionally substituted alkylene or the like; E is COOR?4~ or the like; G is optionally substituted alkylene; J is optionally substituted alkyl or optionally substituted aryl; and M is sulfur, sulfinyl, sulfonyl, or the lik e.
Patent CA-2367742-A1 (CA)
Title: Apparatus for spinal stabilization
Inventor: FINLEY ERIC
IPC: A61B17/58
Filed: 2000-03-29
Abstract: An apparatus is disclosed for connecting first and second elongated spaced apart spinal rods to one another which includes an elongated body portion, a clamp portion depending from the body portion for engaging a spinal rod, the clamp portion defining a deformable clamp body having opposed clamp arms configured for movement between a first position wherein a spinal rod is received between the opposed clamp arms of the clamp body and a second position wherein the spinal rod is securely engaged by the opposed clamp arms of the clamp body, and structure operatively associated with the clamp body which is configured to effectuate movement of the opposed clamp arms of the clamp body between the first and second positions.
Patent CA-2367969-A1 (CA)
Title: Process of preparing 3s-3-amino-3-aryl propionic acid and derivatives thereof
Inventor: SCOTT LORRAINE
IPC: C07D213/55
Filed: 2000-03-21
Abstract: The present invention is directed to a process for preparing 3S-3-amino-3-ar yl propionic acid and derivatives thereof.
Patent CA-2368041-A1 (CA)
Title: Indolinone compounds as kinase inhibitors
Inventor: LIANG CONGXIN
IPC: A61K31/4439
Filed: 2000-03-22
Abstract: The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds of the invention. The invention also relates to methods of modulating the function of protein kinases using indolinone compounds of the invention and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.
Patent CA-2375748-A1 (CA)
Title: Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
Inventor: MUNK JAMES D
IPC: A61K9/12
Filed: 2000-07-05
Abstract: Pharmaceutical compositions are described that comprise one or more active ingredients selected from the group consisting of anti-infective, anti-inflammatory and anti-mucolytic agents, and particularly to compositions formulated as a solution in a unit dose for aerosol administration to treat chronic sinusitis. The figure discloses the preferred equipment for aerosolized delivery of pharmaceutical solutions. This nebulizer, manufactured by Pari Respiratory Equipment, Inc., for the inventors, produces the desired particle size for affective administration of the solutions in this invention to the sinuses. To use this nebulizer preferably medication is placed in the nebulizer at (A). The nebulizer is then connected to compressor or other source at (B) with tubing supplied. When the airflow is turned on, the patient places the nose piece (C) under their nostrils and breathes normally until the medication solution in the nebulizer begins to sputter and no mist comes out at (C).
Patent CA-2378390-A1 (CA)
Title: Tixocortol pivalate suspension, collutorium based on it and packaging containing it
Inventor: DOAT BERNARD
IPC: A61K47/14
Filed: 2000-07-07
Abstract: The subject of the invention is an aqueous suspension of micronized tixocortol pivalate, in a solution containing a surfactant and a viscosity agent.   The subject of the invention is also a collutorium based on this suspension.   Application for the treatment of inflammations of the laryngeal, buccopharyngeal and rhinopharyngeal region.
Patent CA-2378722-A1 (CA)
Inventor: MORRISON EUAN
IPC: H04B10/2587
Filed: 2000-07-10
Abstract: An optical communications system is provided comprising first and second signalling devices in which a duplex communications link between the signalling devices can be established. The first signalling device includes a retro-reflector and the second signalling device includes at least one light source for directing light towards the retro-reflector. Half-duplex embodiments and full-duplex embodiments are described. A wave division multiplex retro-reflecting communication system is also described.
Patent CA-2379703-A1 (CA)
Title: Procede et composition pour la prophylaxie et le traitement des symptomes lies aux affections de type rhume et d'allure grippale
Inventor: SINGER ROBERT ERNEST JR
IPC: A61K47/02
Filed: 2000-07-28
Abstract: L'invention concerne des procédés pour la prophylaxie et le traitement des symptômes liés aux affections de type rhume et d'allure grippale et/ou la prophylaxie et le traitement de la congestion associée aux affections respiratoires. Les procédés en question consistent à administrer une composition renfermant une phytoalexine à base de stilbène. L'invention concerne également certaines compositions renfermant ladite phytoalexine, qui sont utiles pour les procédés décrits.
Patent CA-2380165-A1 (CA)
Title: Interactive television systems with data collection
Inventor: KNEE ROBERT A
IPC: H04N7/173
Filed: 2000-07-10
Abstract: A system is provided based on user equipment such as a set-top box or computer on which an interactive television application may be implemented. Information may be collected on the television viewing activities of a user and the user's interactions with the interactive television application. The interactive television application may be an interactive television program guide. The collected information may be transmitted to a data collection facility using e-mail protocols, using the communications capabilities of a web browser, using a stand-alone FTP application, or using the communications capabilities of an operating system installed on the user equipment.
Patent CA-2380615-A1 (CA)
Title: Anal incontinence treatment apparatus with energy transforming means
Inventor: FORSELL PETER
IPC: A61N1/378
Filed: 2000-08-01
Abstract: An anal incontinence treatment apparatus includes or uses an operable restriction device implanted in a patient and engaging the colon or rectum to form a restricted fecal passageway. An energy transmission means for wireless transmission of energy of a first form from outside the patient's body is provided. An implanted energy transforming means transforms the energy of the first form wirelessly transmitted by the energy transmission means into energy of a second form, which is used to control and operate the restriction device to vary the size of the restricted fecal passageway.
Patent CA-2382378-A1 (CA)
Inventor: REAYS STEPHEN
IPC: B62D1/04
Filed: 2002-05-02
Abstract: This invention relates to a new type of steering wheel. In it, there are two handles set diagonally in the bottom half of the wheel. These handles spin to aid in turning.They are set very precisely for maximum comfort and control.
Patent CA-2390940-A1 (CA)
Title: Amphibious vehicle
Inventor: HANEY HARRY
IPC: B60F3/00
Filed: 2002-06-19
Abstract: An amphibious vehicle for traversing a body of water or solid terrain such as a layer of ice floating atop the body of water. The vehicle includes a floatable boat hull having an elongate aperture there-through, and a snowmobile for traveling over the solid terrain received in the opening and sealed to the hull in water impervious relation. The snowmobile includes an endless drive track for supporting the hull in spaced relation with solid terrain being traversed and for rearwardly propelling water in the body of water to forwardly propel the vehicle over solid terrain or through the water, and a pair of skis which support the front of the hull in spaced relation with the solid terrain being traversed and include upturned forward ends mounting upstanding rudders for steering the boat hull as the vehicle traverses a body of water.  The hull includes upwardly extending, downwardly opening pockets for receiving the front upturned ends of the skis and stabilizing arms which are coupled between the frame and the skis. Upwardly inclined guides are provided on the underside of the hull for upwardly guiding the skis out of the water onto the ice floating on the water as the vehicle exits the water and moves onto the ice.
Patent CA-2391516-A1 (CA)
Title: Locking container
Inventor: GELARDI JOHN A
IPC: B65D50/04
Filed: 2002-06-25
Abstract: A molded locking element for a package having a flexible paperboard or plastic portion comprising a rigid molded plastic locking mechanism comprising a child resistant trigger release mechanism.
Patent CA-2391686-A1 (CA)
Title: Method for producing spark plug
Inventor: NISHIKAWA KENICHI
IPC: H01T13/20
Filed: 2002-06-26
Abstract: A method for producing a spark plug, the spark plug comprising a center electrode, a metal shell and an alumina ceramic insulator disposed between the center electrode and the metal shell, wherein at least part of the surface of the insulator is covered with a glaze layer, the method comprising the steps of: preparing a plurality of kinds of element glaze powders wherein each kind of the element glaze powders has a different dilatometric softening point and a different linear expansion coefficient compared to other kinds of element glaze powders; coating a surface of the insulator with the plurality of kinds of element glaze powders so as to form a glaze powder layer; and baking the glaze powder layer to the surface of the insulator so as to form the glaze layer by heating the glaze powder layer.
Patent CA-2392881-A1 (CA)
Inventor: DICKMAN ANTHONY J
IPC: H01M8/24
Filed: 2001-03-27
Abstract: A fuel cell system having partial and/or total redundancy of at least one operational component, such as a redundancy of fuel cell stacks and/or fuel processors. In some embodiments, the fuel cell system includes a plurality o f fuel cell stacks adapted to deliver the same maximum rated power output as a  comparative fuel cell system having only a single fuel cell stack. In some embodiments, the fuel cell system includes a plurality of fuel cell stacks adapted to deliver more than the maximum rated power output of the comparati ve fuel cell system. In some embodiments, the fuel cell system includes a plurality of fuel cell stacks having at least n+1 (or total) redundancy compared to a fuel cell system having only a single fuel cell stack. In some  embodiments, the fuel cell system includes a control system and/or structure  adapted to limit the applied load to the system.
Patent CA-2393456-A1 (CA)
Title: Vinyl-ethers contenant du fluor
Inventor: HINTZER KLAUS
IPC: C07C43/17
Filed: 2000-04-20
Abstract: L'invention concerne un nouveau procédé de préparation de perfluorovinyl-éthers. Ledit procédé consiste à prévoir un précurseur hydrocarbure pouvant être partiellement halogéné, à fluorer le précurseur, de manière qu'un intermédiaire perfluoré soit produit, et à convertir l'intermédiaire perfluoré en l'éther perfluoré voulu. Des nouveaux perfluorovinyl-éthers sont également décrits.
Patent CA-2393736-A1 (CA)
Inventor: BOURREAU JEAN-MARIE
IPC: B65D51/24
Filed: 2000-12-11
Abstract: The invention concerns a cap (1) comprising as assembly consisting of: a) a plastic insert (2) comprising a head (3) with closure means (31, 32) and a threaded skirt (4), and b) a metal wall. The invention is characterised in that: 1) said metal wall (5) covers all or part of the outer surface of said insert (2) and includes at least a metal skirt (51) for receiving said skirt (4) of said insert (2); said metal skirt (51) includes an edge (510) crimped to said insert (2) so as to assemble together said metal wall (5) and said insert (2); 3) said cap comprises means designed to provide weight and/or volume to the part of said cap located above said sealing closure means (31, 32).
Patent CA-2395656-A1 (CA)
Title: Anti tamper encapsulation for an integrated circuit
Inventor: KOMMERLING OLIVER
IPC: G06F21/87
Filed: 2000-12-27
Abstract: An integrated circuit device comprising: a circuit which uses encryption; and a protective member (e.g. encapsulation packaging layer) which reduces access to the circuit; in which the circuit is responsive to at least one physical parameter of the protective member to apply the encryption and/or decryption (e.g. by reading the key therefrom), so that tampering with the protective member to gain access to the circuit causes the encryption and/or decryption to function differently.
Patent CA-2395700-A1 (CA)
Title: Antibodies specific for proteins having polyglutamine expansions
Inventor: FINKBEINER STEVEN
IPC: C07K16/18
Filed: 2001-01-05
Abstract: Antibodies, as well as binding fragments and mimetics thereof, that specifically bind to polyglutamine expansion containing proteins, e.g. mutant huntingtin protein, mutant androgen receptor, mutant dentatorubral-pallidoluysian atrophy gene, are provided. The subject binding agents, e.g.  antibodies, fragments and mimetics thereof, etc., are characterized in that they bind to the target polyglutamine expansion containing protein in a manner that differs from the 1C2 antibody, e.g. in terms of affinity, avidity, and the like. Also provided are methods of screening compounds for polyglutamine expansion protein binding modulation activity, as well as pharmaceutical compositions of such agents. In addition, methods and devices for screening samples for the presence of polyglutamine expansion containing proteins, e.g.  mutant huntingtin protein mutant androgen receptor, mutant dentatorubral-pallidoluysian atrophy gene, are provided. Finally, nucleic acids encoding the subject antibodies and methods for their expression, including in therapeutic treatment protocols, are provided.
Patent CA-2396215-A1 (CA)
Title: Garment hanger having a removable size indicator
Inventor: OLK OLAF
IPC: A47G25/14
Filed: 2000-05-15
Abstract: A garment hanger having a releasable size indicator (126). The garment hanger including a hook for suspending the hanger on a support and a body connected to the hook; the hanger having at least one web for removably securing a size indicator to the hanger, the web having a fixed latch (110) and a pivoting latch (112);  and a size indicator having at least one engagement abutment and fingers for engaging the fixed and pivoting latches such that the size indicator is secured on the web during normal use, but wherein the size indicator may be released from the web when the pivoting latch is pivoted out of engagement with the fingers of the size indicator.
Patent CA-2396442-A1 (CA)
Title: Procedes et systeme bases sur des unites d'execution utilisant la puissance de traitement informatique en veille d'au moins un ordinateur pour resoudre des problemes scientifiques complexes
Inventor: KEEFER CHRISTOPHER E
IPC: G06F15/16
Filed: 2000-11-29
Abstract: L'invention concerne des procédés et des système à base d'unités d'exécution utilisant la puissance de traitement informatique en veille d'au moins un ordinateur en réseau, qui comprend au moins un serveur et un client. Le serveur stocke des données et des descriptions de travaux relatives à un problème scientifique complexe, et fournit des descriptions de travaux et des parties de données à des clients en réponse à leurs demandes. Chacun de ces clients lance une première unité d'exécution en veille afin d'extraire des descriptions de travaux du serveur, et une seconde unité d'exécution en veille afin de demander des données à un serveur et d'exécuter le travail spécifié dans la description de travaux. Les première et seconde unités d'exécution en veille sont automatiquement ordonnés pour être exécutés par le système d'exploitation.
Patent CA-2396655-A1 (CA)
Title: Treatment of seeds and/or plants with pseudomonas culture
Inventor: WOLFGANG ARNDT
IPC: A01N63/27
Filed: 2000-11-04
Abstract: The invention relates to Pseudomonas strain termed Proradix, deposited under the Accession number PRORADIX - DSM  13134, for use in the treatment of seeds or plants.
Patent CA-2403219-A1 (CA)
Title: Method for defining a relationship between an account and a group
Inventor: BLAGG LYNN HOLM
IPC: G06Q40/00
Filed: 1999-12-30
Abstract: Published without an Abstract
Patent CA-2403445-A1 (CA)
Title: Improved coating composition
Inventor: PRESSLEY OZZIE MOORE
IPC: C09D143/02
Filed: 2002-09-16
Abstract: An improved aqueous coating composition which includes a bimodal copolymer.     Methods of using an aqueous coating composition which includes a bimodal copolymer.
Patent CA-2404384-A1 (CA)
Title: Substituted 1,3-thiazole compounds, their production and use
Inventor: MIWATASHI SEIJI
IPC: C07D417/04
Filed: 2001-03-29
Abstract: (1) A 1,3-thiazole compound of which the 5-position is substituted with a 4-pyridyl group having a substituent including no aromatic group or (2) a 1,3-thiazole compound of which the 5-position is substituted with a pyridyl group having at the position adjacent to a nitrogen atom of the pyridyl group a substituent including no aromatic group has an excellent p38 MAP kinase inhibitory activity.
Patent CA-2405111-A1 (CA)
Title: Composite polymer/polymer material with high content in amorphous dispersed phase and preparation method
Inventor: MICHEL ALAIN
IPC: B29C48/405
Filed: 2001-04-06
Abstract: The invention concerns a micro-composite polymer/polymer material comprising an amorphous polymer (I) forming a dispersed phase localised inside a thermoplastic or elastomeric polymer (II) forming a matrix, the glass transition temperature of polymer (I) forming a dispersed phase being higher by at least 20 ·C than the melting or softening point of matrix-forming polymer (II), and the amorphous polymer content (I) forming the dispersed phase being not less than 40 wt. %. The invention also concerns a method for obtaining said material comprising steps which consist in: extruding, at regulated temperature, said melted polymer mixture, said regulating temperature being decreasing from the feeding zone (A) to the die zone (F) of said extruding machine (1) so that the material temperature in said die zone (F) is lower than the temperature of recrystallisation or solidification of polymer (II), and higher than the melting or softening point of amorphous polymer (I); and cooling at room temperature the resulting micro-composite material.
Patent CA-2406994-A1 (CA)
Title: Medical device with shield having a retractable needle
Inventor: BOTICH MICHAEL J
IPC: A61M5/32
Filed: 2001-04-18
Abstract: Needle-bearing medical devices (10, 100, 200, 300, 400) are provided for fluid infusion, fluid transfusion, and inserting a guide wire. After use the needle (65, 165, 265, 365) is shielded to render the contaminated needle safe to prevent inadvertent needle sticks. The device includes a housing (20, 120, 220, 320, 420) and a needle having a sharpened tip. A biasing element (60, 160, 260, 360, 460) biases the needle (65, 165, 26, 365, 465) toward a position in which the sharpened tip is shielded.
Patent CA-2408374-A1 (CA)
Inventor: BERKOVIC SAMUEL FRANK
IPC: C12Q1/02
Filed: 2001-05-11
Abstract: A point mutation in the .beta.2 subunit of an nicotinic acetylcholine receptor producing a V287M transition is associated with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE).
Patent CA-2408469-A1 (CA)
Inventor: MACKAY GEORGE
IPC: H04L29/06
Filed: 2002-10-17
Abstract: A cellular phone payment system for making payment for goods or service, which comprises three parts: 1) a user's cellular phone, which could also be any other form of mobile communications device provided that it can be linked to the public phone system, 2) an on-street vending machine, and 3) a remote payment auto-attendant computer with modem, which can be accessed by the public phone system. The user's cellular phone is the communications link or conduit used to access the remote payment auto-attendant computer, as well as to relay instructions to the user once user verification has been completed. The user calls the auto-attendant, authenticates his/her identity, and then is given instructions on how to make remote cellular payment on the vending machine in question. The user follows the instructions, which consists of indicating what good/service is being purchased, and then entering a sequence of challenges and responses between the remote auto-attendant computer and the vending machine to validate and confirm payment on the machine. The user uses the phone keypad and the keypad on the vending machine as the data entry means. Once the payment cycle is successfully completed, the payment will have been securely authenticated, the good/service provided, and the users preferred payment method, has been debited the corresponding amount. The payment will have been accomplished with the vending machine offline.
Patent CA-2412270-A1 (CA)
Inventor: JONES PHILIP STEPHEN
IPC: A61P43/00
Filed: 2001-04-30
Abstract: L'invention concerne de nouveaux dérivés pyrrole et leur procédé de fabrication, des compositions pharmaceutiques et leur utilisation en médecine, ainsi que des esters hydrolysables ou des éthers de ceux-ci ou des sels pharmaceutiquement acceptables de ceux-ci. Les composés représentés par la formule (I) sont, en particulier, des inhibiteurs de l'enzyme de la reverse-transcriptase du virus humain de l'immunodéficience impliquée dans la réplication virale. De ce fait, les composés de l'invention peuvent avantageusement être utilisés comme agents thérapeutiques dans un processus induit par le HIV. L'invention concerne les nouveaux composés représentés par la formule (I) dans laquelle R?1¿ représente alkyle, cycloalkyle, aryle ou hétérocyclyle; R?2¿ représente alkyle, cycloalkyle, aryle ou hétérocyclyle; R?3¿ représente hydrogène, alkyle, cycloalkyle, aryle ou hétérocyclyle; R?4¿ représente hydrogène, alkyle, carboxyle, C(=O)R, CONR'R'', cyano ou alcényle, où R représente hydrogène, alkyle, alcoxy, trifluorométhyle, méthyl-oxy-carbonyle ou éthyl-oxy-carbonyle, et R' et R'', représentent indépendamment l'un de l'autre, hydrogène, alkyle ou aryle; R?5¿ représente alkyle, aryle ou un groupe -Z-C(=O)R''' où Z représente une liaison simple ou -CH=CH-, et où R''' représente hydrogène ou alkyle; X représente S, S(O), S(O)¿2?, O, N(alkyl) ou X-R?2¿ représentent ensemble CH¿2?-aryle ou CH¿2?-hétérocyclyle à condition que seul l'un de R?3¿ ou R?4¿ représente hydrogène et alkyle et que R?3¿ ne représente pas CF¿3?.
Patent CA-2412885-A1 (CA)
Title: Porous celecoxib matrices and methods of manufacture thereof
Inventor: RANDALL GREG
IPC: A61K9/20
Filed: 2001-06-15
Abstract: Celecoxib is provided in a porous matrix form wherein the dissolution rate of the drug is enhanced when the matrix is contacted with an aqueous medium. The porous matrix yields upon contact with an aqueous medium nanoparticles and microparticles of celecoxib having a mean diameter between about 0.01 and 5 µm and a total surface area greater than about 0.5 m2/mL. The dry porous matrix preferably is in a dry powder form having a TAP density less than or equal to 1.0 g/mL. The porous celecoxib matrices preferably are made using a process that includes: (i) dissolving celecoxib in a volatile solvent to form a drug solution; (ii) combining at least one pore forming agent with the drug solution to form an emulsion, suspension, or second solution; and (iii) removing the volatile solvent and pore forming agent from the emulsion, suspension, or second solution to yield the dry porous matrix of celecoxib.  The resulting porous matrix has a faster rate of dissolution following administration to a patient, as compared to non-porous matrix forms of the drug.