baber/WOPTO huggingface dataset:
Patent CA-2424585-A1 (CA)
Title: Remedies for retinal nerve diseases containing 1,2-ethanediol derivatives or salts thereof
Inventor: ONO SATOSHI
IPC: A61P27/02
Filed: 2001-10-04
Abstract: 1,2-Ethanediol derivatives represented by the following general formula [1] or salts thereof wherein R1 represents an optionally substituted heterocyclic group; R2 represents hydrogen or a hydroxyl-protective group; R3 represents hydrogen or lower alkyl; n R4s and R5s may be either the same or different and each represents hydrogen or lower alkyl; R6 represents optionally substituted amino or ammonio; and n is an integer of from 1 to 6; show a retinal nerve cell protecting effect in a glaucoma model and a rat retinal ischemia recanalization model. Thus, they inhibit retinal nerve cell death and, therefore, are useful as preventives and remedies for retinal nerve diseases such as glaucoma, diabetic retinopathy, retinal artery occlusion, retinal vein occlusion, macular degeneration and retinopathy of prematurity.
Patent CA-2425842-A1 (CA)
Inventor: MCCABE DOROTHY
IPC: A61K47/48
Filed: 2001-10-30
Abstract: The invention relates to methods of treating a blood disorder in a mammal wi th an interleukin-1 (IL-1) inhibitor. The invention also relates to methods of treating a blood disorder in a mammal with an IL-1 inhibitor, a TNF inhibito r and an erythropoietin (EPO) receptor agonist. The invention also relates to compositions of an IL-1 inhibitor and compositions of an IL-1 inhibitor, a T NF inhibitor and an EPO receptor agonist.
Patent CA-2426540-A1 (CA)
Inventor: WOODWARD ROBERT
IPC: C12Q1/68
Filed: 2001-10-22
Abstract: L'invention concerne l'évaluation du niveau d'expression génique d'un leucocyte utilisé pour identifier des oligonucléotides à partir de bibliothèques candidates d'expression génique. Ces bibliothèques d'expression sont généralement immobilisées sur une matrice. L'invention concerne également un oligonucléotide de diagnostic réglé de façon à analyser des maladies associées à un leucocyte.
Patent CA-2426675-A1 (CA)
Inventor: ALVARADO JUAN C
IPC: H04L29/08
Filed: 2001-11-14
Abstract: Near real-time transfer of a datafile from a first computer to a second computer over a computer network. These computers are operated such that on the first computer a server side script, responsive to a download request from the second computer, operable to launch an httpstreamproducer and to read and write data over the computer network. The httpstreamproducer is operable to read a designated source file and simultaneously write data from the source file into a return-data-buffer connected to the server-side script and a read-while-write mechanism allowing the httpstreamproducer to read data from the designated source file while the designated source file is being written. The second computer has a transaction handler class, each instance of which is operable to read and write data produced by an httpstreamproducer over the computer network and to write blocks of data to a destination simultaneously with receiving data from the computer network.
Patent CA-2428763-A1 (CA)
Title: Device for attaching an implement to a lifting unit
Inventor: PERRIN LAURENT
IPC: E02F3/36
Filed: 2003-05-15
Abstract: The invention pertains to a device for attaching an implement to a lifting unit, in particular, to a front-end loader, wherein the implement and the lifting unit can be connected to one another by a movable bar that can be displaced from a locki ng position into an unlocking position by an externally activated actuator. The actuator is coupled to the bar by a coupling device designed such that a driving connection between the actuator and the bar is only produced when the actuator is activated. This makes it possible to displace the bar manually, as well as in an actuator-operated fashion.
Patent CA-2430518-A1 (CA)
Title: Guanidine and amidine derivatives as factor xa inhibitors
Inventor: ZOLLER GERHARD
IPC: A61K31/4545
Filed: 2001-11-28
Abstract: The present invention relates compounds of the formula (I), in which R0, Q, X, Q', D, R10 and V have the meanings indicated in the claims. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa(Fxa) and/or factor VIIa(FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formula (I), their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.
Patent CA-2430636-A1 (CA)
Title: Universal electrical energy saver
Inventor: FA GEORGE
IPC: G05F1/70
Filed: 2003-05-26
Abstract: A universal electrical energy saver to recuperate power losses comprised of a bank of condensers connected in parallel; a bank of resistors with some connected in parallel while others are connected in series; a transformer to step down the voltage to power up a small electronic circuit board which serves to absorb the lost power and protect the rest of the circuitry against overload; a line plugging into a power outlet to connect the universal electrical energy saver with the rest of the electrical circuit.
Patent CA-2434597-A1 (CA)
Inventor: SALMON XAVIER
IPC: G02B6/28
Filed: 2003-07-11
Abstract: Coupleur optique (1) comportant deux fibres optiques (2, 3), chacune des fibres optiques reliant à une première extrémité (9, 10) un émetteur (4) et ensuite chacune de ces fibres étant reliée indépendamment à deux récepteurs (6, 8) indépendants. Au niveau de l'émetteur 4, les fibres sont dénudées pour être insérées dans une même férule (15) qui peut être présentée en face du faisceau optique émis par l'émetteur. La zone intermédiaire dénudée entre la férule et la portion de câble non dénudé, est protégée par une première gaine (21) à l'intérieur de laquelle les fibres optiques nues sont flottantes et par une deuxième gaine de protection.</SDOA B>
Patent CA-2435860-A1 (CA)
Title: Method and apparatus for feeding wire to a welding arc
Inventor: HUTCHISON RICHARD M
IPC: B23K9/133
Filed: 2003-07-23
Abstract: A method and apparatus for feeding wire in a welding system include one or more motors disposed adjacent the wire to drive it. A wire feed motor is also disposed along the wire path, and is closer to the source of wire than the torch, and closer to the source than the one or more motors. The motors may be a pair motors disposed on opposite sides of the wire and move the wire to and away from an arc end of a torch. They preferably reversing the direction of the wire within one process cycle. The or more motors may be a stepper motor, a servo motor, a zero backlash motor, a gearless motor, a planetary drive motor, or a linear actuator (such as a piston), in various embodiments.
Patent CA-2439475-A1 (CA)
Title: Carbamate compounds for use in preventing or treating bipolar disorder
Inventor: TWYMAN ROY E
IPC: A61P25/24
Filed: 2002-02-21
Abstract: This invention is directed to a method for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I): Formula (I);  wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1 and R2 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
Patent CA-2441726-A1 (CA)
Inventor: RICHARDSON TIMOTHY M
IPC: G02B21/06
Filed: 1999-02-24
Abstract: A novel illuminator for a field microscope, which takes the place of the condenser and the light source and collimating optics in a traditional microscope, is described. The illuminator is described in several embodiments which cover bright-field transmitted light, bright-field reflected light, dark-field transmitted light and dark-field reflected light as well as uni-directional oblique and slit-ultra illumination techniques. The light sources are modular so that they can be interchanged on the microscope, and they feature ultra-low power and current consumption, integral dimming control, battery power and light weight. Optically the illuminators offer extremely flat field illumination along with excellent colour correction or selectable narrow wavelengths. The illuminators are characterized by high optical efficiency and small size.
Patent CA-2441745-A1 (CA)
Title: Polymers and oligomers, their synthesis, and electronic devices incorporating same
Inventor: EPSTEIN ARTHUR
IPC: C07D215/14
Filed: 2002-03-12
Abstract: The invention relates to polymers and oligomers, methods of their synthesis, and electronic devices comprising them.
Patent CA-2442051-A1 (CA)
Inventor: SALVESTRO ALDO
IPC: B41N3/00
Filed: 2003-09-22
Abstract: A method and apparatus are provided for the manipulation of a sleeve onto and off of a cylinder. A sleeve mounted on a handling shaft is equipped with a substantially airtight slideable end cap at its distal end. During mounting, axial alignment is provided when the handling shaft is engaged with the free end of the cylinder. A plurality of apertures on the cylinder's exterior surface conduct pressurized air, which expands the sleeve by exerting radial fluid pressure on its inside surface. A vacuum source actively evacuates the air from the sleeve's interior drawing the sleeve onto the cylinder. To remove the sleeve fluid pressure is reasserted exerting an axial force against the substantially airtight end cap. An auxiliary air supply is selectively activated to aid in sleeve removal.
Patent CA-2443234-A1 (CA)
Inventor: HARRINGTON EDMUND
IPC: A61P1/16
Filed: 2002-04-10
Abstract: The present invention provides compounds of formula I: wherein A is N or CR, and R1, G and R2, are as described in the specification. These compounds are inhibitors of protein kinase, particularly inhibitors of Src mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
Patent CA-2444488-A1 (CA)
Inventor: CHENG WU-CHENG
IPC: B01J35/02
Filed: 2002-03-28
Abstract: A catalyst useful in cracking of hydrocarbon feedstock comprising particulate material composed of at least 70 weight percent zeolite and the remainder substantially composed of silica sol, alumina sol or mixtures thereof; wherein the particulate material has a kinetic conversion activity of at least about 3; and compositions for fluid catalytic cracking of petroleum feedstock comprising said catalyst and a second particulate material having a kinetic conversion activity of less than 3 wherein said catalyst composition having a kinetic conversion activity of at least about 2.
Patent CA-2445060-A1 (CA)
Title: Liner or insulator with nonlaminate acoustical and thermal insulating layer
Inventor: POOLE PAUL W
IPC: B32B27/12
Filed: 2002-05-28
Abstract: A hood, dash, firewall or engine cover liner (10) is provided for a vehicle. The liner includes a nonlaminate acoustical and thermal insulating layer of polymer fiber (12) that shows no signs of any thickness increase, delamination, deterioration or any undesirable effect which may affect performance for at least 330 hours when maintained at a temperature of at least approximately 150~C (302~F). The liner may include a relatively high density, nonlaminate skin of polymer fiber (14) and/or one or more facing layers (16, 20) constructed from polymer material.
Patent CA-2445333-A1 (CA)
Inventor: SAKAI TERUYUKI
IPC: A61P35/00
Filed: 2002-04-26
Abstract: An object of the present invention is to provide compounds having potent antitumor activity. The compounds according to the present invention are compounds represented by formula (I) or pharmaceutically acceptable salts or solvates thereof:  (see formula I) wherein X and Z represent CH or N; Y represents O or S;  R1, R2, and R3 represent H, alkoxy or the like; R4 represents H; R5, R6, R7, and R8 represent H, halogen, alkoxy or the like; R9 and R10 represent H, alkyl or the like; and R11 represents optionally substituted azolyl.
Patent CA-2447458-A1 (CA)
Title: System and method for managing query access to information
Inventor: DANTRESSANGLE PATRICK
IPC: G06F16/17
Filed: 2003-10-29
Abstract: A system and method for supporting named memory variables in an information retrieval system comprising a relational database. PUBLIC and PRIVATE named memory variables can be created, referenced, modified or deleted using SQL statements. The informati on retrieval system allocates a memory area as a named variable storage space for storing named memory variables. System catalogs may be used for storing information about PUBLIC, SECURE PUBLIC, SECURE PRIVATE, and pre-defined named memory variables. PUBLIC and PRIVATE named memory variables can be used for transferring information between SQL statements of one or more sessions, or for retrieving system information from the relational database. Both PUBLIC and PRIVATE types can be defined as SECURE named memory variables requiring specific authorization privileges to read or write to the variable.
Patent CA-2447944-A1 (CA)
Inventor: WILKINSON BRADLEY M
IPC: G06Q30/02
Filed: 2002-04-30
Abstract: L'invention concerne un ensemble protecteur d'aiguille à protecteur d'aiguille articulé. Une rampe est prévue à proximité de la charnière d'articulation reliant le protecteur à l'ensemble base. De préférence, la rampe est flexible. Soumise à une compression, elle exerce une contrainte en souplesse sur le protecteur, contraignant celui-ci dans une position angulaire préférée par rapport à la seringue. Le protecteur passe d'une position entièrement ouverte, avec inclinaison selon un certain angle par rapport à la seringue, à une position fermée d'enveloppement de la seringue. De préférence, un ou plusieurs éléments de verrouillage sont prévus sur le protecteur, pour maintenir celui-ci dans une position fermée de protection de l'aiguille.
Patent CA-2448950-A1 (CA)
Title: Coaxial heat sink connector
Inventor: PAYNE SHAWN ROBERT
IPC: H01R13/646
Filed: 2003-11-12
Abstract: A coaxial heat sink connector for providing a thermal path from the conductors associated with a coaxial cable connector to a heat sink includes a center conductor, an outer conductor, an insulative layer, TNC connector(s) and a thermal element. The outer conductor is positioned around the center conductor and the insulation layer is positioned between. The insulation layer has high thermal conductivity to provide substantial heat transfer between the center and outer conductors. TNC connector(s) are positioned at the end(s) of the connector and electrically coupled to the center and outer conductors. The thermal element is coupled to the outer conductor to conduct heat from the outer conductor to the heat sink. Heat sink connector providing transfer paths for bolted together RF components as well as individual RF power components.
Patent CA-2452161-A1 (CA)
Title: Fire fighting method and apparatus
Inventor: O'DWYER JAMES MICHAEL
IPC: A62C27/00
Filed: 2002-07-03
Abstract: A fire fighting apparatus (20) for fighting a fire (10) having a relatively large area or volume (11, 12), said apparatus including a targeting system (23) for identifying a target area to be doused with fire retardant and an ordnance (21) for discharging a multiplicity of projectiles (22) having the fire retardant contained therein (32). The ordnance of the apparatus includes at least one barrel assembly (30), said at least one barrel assembly having a barrel (39), a plurality of projectiles (35) axially disposed within the barrel for operative sealing engagement with the bore of the barrel (39), and discrete propellant charges (36) for propelling respective projectiles sequentially through the muzzle of the barrel, whereby said fire retardant is dispersed over the target area or within the target volume.
Patent CA-2452814-A1 (CA)
Title: Toy for use with vertical surfaces
Inventor: SHULER ERIC THOMAS
IPC: G09B5/06
Filed: 2003-12-10
Abstract: An interactive educational apparatus is described. The educational toy apparatus includes an indicium containing structure and a base unit capable of being vertically attached to a vertical surface such as a refrigerator door. The indicium containing structure is capable of being attached to the base unit so that the indicium containing structure and the base unit are vertically oriented.
Patent CA-2454157-A1 (CA)
Inventor: SASAMINE KAZUO
IPC: A61M5/14
Filed: 2002-07-09
Abstract: The invention tissue injection catheters are designed to facilitate injection of a therapeutic or diagnostic agent to an interior body cavity, especially the myocardium or epicardium of the heart with precisely controlled depth penetration. The invention injection catheters, which include mechanisms for precisely controlling the length of needle tip exposed for tissue penetration, are designed to be used in an assemblage with a sterile container and delivery actuator for reinjection of autologous cell-containing fluids, such as autologous bone marrow aspirate. In preferred embodiments, the assemblage is designed to be hand-held. When used in such an assemblage, the invention catheters are particularly useful as a gene delivery device to effect angiogenesis of ischemic areas of the heart.
Patent CA-2454224-A1 (CA)
Inventor: HENTHORN DAVID A
IPC: G06Q50/00
Filed: 2002-07-18
Abstract: L'invention se rapporte à un pense-bête pour médicaments et à un procédé et un appareil conformes (10). Un calendrier à date spécifique comprenant des informations sur le dosage quotidien est généré sous la forme d'une étiquette (62, 66) ou d'une feuille comportant des informations (60, 67).
Patent CA-2458181-A1 (CA)
Inventor: BENSON RODGER WILLIAM
IPC: H04N5/45
Filed: 2004-02-20
Abstract: A method, application interface, and medium is provided for presenting a variety of data representations in a screen-area inset. The inset(s) can be one or more bounded portions of a graphical user interface. The inset offers a picture-in-picture type of functionality to present videos, data, pictures, audio, and other data representations in a persistently viewable screen area that does not consume the entirety of a display device. The API includes instructions to allow software components to use the inset. The method includes receiving one or more event requests related to the inset, communicating them to a software application or operating system, receiving one or more data sets to satisfy the event requests, and communicating the data sets to the original software application to present a data representation in the inset.
Patent CA-2468042-A1 (CA)
Title: Production of ammonium salts of aromatic carboxylic acids
Inventor: FRANKE DIRK
IPC: C07C63/04
Filed: 2002-12-03
Abstract: A method for the production of ammonium salts of aromatic carboxylic acids b y reaction of an aromatic carboxylic acid with ammonia in an aprotic solvent i s disclosed. Said reaction is carried out in a closed vessel and a solution of the aromatic carboxylic acid in an aprotic solvent and gaseous ammonia are continuously introduced into the vessel, such that a partial pressure of ammonia of 0.1 to 3 bars is maintained in the gas chamber of the vessel and a suspension of the ammonium salt separates out in the aprotic solvent. The method permits the production of ammonium salts with defined crystal size an d a narrow size distribution.
Patent CA-2468207-A1 (CA)
Title: Treatment of fabric articles
Inventor: PERKINS CHRISTOPHER MARK
IPC: D06L1/00
Filed: 2002-12-19
Abstract: Methods and compositions to treat fabrics with lipophilic fluid and a hydrophobic chelant are provided by the present invention.
Patent CA-2468949-A1 (CA)
Inventor: RAPOSO PAUL
IPC: G06Q10/10
Filed: 2002-12-26
Abstract: L'invention concerne un système de suivi d'actifs comprenant une base de données de suivi de biens à accès universel. Cette base de données est fondée sur un modèle organisation-bien-individu et utilise une recherche à correspondance étroite pour la mise en correspondance des objets perdus et trouvés. N'importe quel type de bien peut être signalé comme trouvé, enregistré et signalé comme perdu, tout bien récupéré pouvant ainsi être restitué à son propriétaire. Les divers modes de réalisation de ce système comprennent un accès en ligne permettant à un utilisateur ou à une organisation d'enregistrer un objet sur la base des caractéristiques de l'objet ou d'un code d'étiquette apposée. Si l'objet est perdu à cause d'un accident, d'un vol ou d'un endommagement, le système peut être utilisé pour enregistrer l'objet perdu et pour produire des rapports et des informations de demande d'indemnité. Un utilisateur qui trouve un objet peut enregistrer cet objet comme un objet trouvé. Lorsqu'une correspondance est établie entre un objet perdu enregistré et un objet trouvé enregistré, ledit système peut être utilisé pour restituer l'objet à son propriétaire.
Patent CA-2469480-A1 (CA)
Title: Use of biomolecular targets in the treatment and visualization of tumors
Inventor: FOEHR ERIK
IPC: C12Q1/68
Filed: 2002-12-23
Abstract: The present invention relates to the use of a protein that is differentially expressed in primary brain tumor tissues, as compared to normal brain tissue s, as a biomolecular target for tumor treatment therapies. The protein is also expressed in tissues from adenocarcinoma, non-melanoma, and renal carcinoma cells. Immunotherapeutic and immunoimaging agents that specifically bind to an identified brain tumor target protein are provided. The present invention al so provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention.
Patent CA-2469539-A1 (CA)
Inventor: BROZENICK NORMAN J
IPC: B32B7/08
Filed: 2004-06-03
Abstract: The present invention is directed to a method of preparing an article of manufacture. The method includes bringing at least a portion of a heated thermoplastic sheet into contact with at least a portion of the first surface of a support having a plurality of perforations. A vacuum is formed on the second surface of the support, and portions the heated thermoplastic sheet are drawn through the perforations of the support and to the second surface side of the support. Thermoplastic attachment heads are formed on the second surface side of the support, from the thermoplastic material of the sheet that is drawn through the perforations.      The thermoplastic sheet and the support are fixedly attached one to the other by means of the edges of the perforations being embedded in the thermoplastic material of the sheet drawn therethrough, and the thermoplastic attachment heads. Also disclosed are articles of manufacture, such as interior and exterior automotive body panels and components.