baber/WOPTO huggingface dataset:
Patent CA-2362392-A1 (CA)
Title: Heterocyclic derivatives as inhibitors of factor xa
Inventor: CAULKETT PETER WILLIAM RODNEY
IPC: A61K31/495
Filed: 2000-02-08
Abstract: The invention relates to heterocyclic derivatives, or pharmaceutically-acceptable salts thereof, of formula (I) wherein: A is an optionally substituted 5- or 6-membered monocyclic aromatic ring containing 1, 2 or 3 ring heteroatoms selected from oxygen, nitrogen and sulphur atoms; which possess antithrombotic and anticoagulant properties and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect.
Patent CA-2362715-A1 (CA)
Title: Quinazoline derivatives as angiogenesis inhibitors
Inventor: MCKERRECHER DARREN
IPC: C07D417/14
Filed: 2000-02-08
Abstract: The invention relates to the use of compounds of formula (I), wherein ring C  is an 8, 9, 10, 12 or 13-membered bicyclic or tricyclic moiety which optionally may contain 1-3 heteroatoms selected independently from O, N and S; Z is -O-, -NH-, -S-, -CH2- or a direct bond; n is 0-5; m is 0-3; R2 represen ts hydrogen, hydroxy, halogeno, cyano, nitro, trifluoromethyl, C1-3alkyl, C1- 3alkoxy, C1-3alkylsulphanyl, -NR3R4 (wherein R3 and R4, which may be the sam e or different, each represents hydrogen or C1-3alkyl), or R5X1- (wherein X1 a nd R5 are as defined herein; R1 represents hydrogen, oxo, halogeno, hydroxy, C1 - 4alkoxy, C1-4alkyl, C1-4alkoxymethyl, C1-4alkanoyl, C1-4haloalkyl, cyano, amino, C2-5alkenyl, C2-5alkynyl, C1-3alkanoyloxy, nitro, C1-4alkanoylamino, C1- 4alkoxycarbonyl, C1-4alkylsulphanyl, C1-4alkylsulphinyl, C1-4alkylsulphonyl,  carbamoyl, N-C1-4alkylcarbamoyl, N,N-di(C1- 4alkyl)carbamoyl, aminosulphonyl, N-C1-4alkylaminosulphonyl, N,N-di(C1-4alkyl)aminosulphonyl, N-(C1- 4alkylsulphonyl)amino, N-(C1-4alkylsulphonyl)-N-(C1- 4alkyl)amino, N,N-di(C1-4alkylsulphonyl)amino, a C3-7alkylene chain joined to two ring C carbon atoms, C1-4alkanoylaminoC1-4alkyl, carboxy  or a group R56X10 (wherein X10 and R56 are as defined herein); and salts thereof, in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals, processes for the preparation of such compounds, pharmaceutical compositions containing a compound of formula (I) or a pharmaceutically acceptable salt thereof as active ingredient and compounds of formula (I). T he compounds of formula (I) and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a numbe r of disease states including cancer and rheumatoid arthritis.
Patent CA-2367953-A1 (CA)
Title: Segmented roll
Inventor: ERONEN PEKKA
IPC: B65H23/025
Filed: 2000-03-21
Abstract: The invention relates to a segmented roll comprised of a plurality of end-to-end mounted roll segments (10, 10'), each adapted to rotate on bearings supported on a separate support shaft (11). In both axial end surfaces of the support shafts (11) of the roll segments (10) there are coupling means such as an annular projection and an annular recess serving to disengageably connect two adjactent roll segments (10) to each other. The support shaft (11) contains of at least two parts (16, 18) whose mutual disposition is made alterable for the purpose of altering the axial length of the support shaft (11) so much that the coupling means (29, 41) of the facing axial ends of two adjacent roll segments (10) can be engaged and disengaged with each other. This arrangement makes it possible to change a single roll segment from the central area of the segmented roll without the need for disassembling the entire row of roll segments.
Patent CA-2370075-A1 (CA)
Title: Ultrasound imaging device
Inventor: LEVKOVITZ ZEEV
IPC: A61B8/00
Filed: 2000-04-14
Abstract: Ultrasound-based imaging device (1) and software operated method are presented for monitoring a body part and generating data indicative of a three-dimensional image of an internal structure of the body part. The device (1) is portable and comprises a substantially elastic cover (1A) for covering the body part, wherein the cover is coupled to a control unit (1B) and is connectable to a computer device. The cover carries an array of ultrasonic transceivers (5), each of a kind emitting a beam of ultrasonic waves for irradiating an area within a region covered by the cover, and detecting signal response of the irradiated area. The transceivers (5) are arranged in at least two spaced parallel groups. The transceivers of each group are arranged in a spaced-apart relationship, the space between each two adjacent transceivers in the group being such that an overlap exists between the areas irradiated by the adjacent transceivers.
Patent CA-2370467-A1 (CA)
Inventor: LEE EUN-HAE
IPC: C12P21/02
Filed: 1999-04-23
Abstract: The invention relates to the fields of molecular biology, bacteriology and industrial fermentation. More specifically, the invention provides isolated nucleic acid molecules encoding the three subunits of a novel, membrane-boun d, Gluconobacter oxydans sorbitol dehydrogenase (SDH) of the invention and vectors and host cells containing said isolated nucleic acid molecules. The invention further provides isolated polypeptides for the three subunits of t he SDH enzyme of the invention, and processes for the production of L-sorbose a nd 2-keto-L-gulonic acid.
Patent CA-2371352-A1 (CA)
Inventor: HUG ROBERT G
IPC: H04L29/06
Filed: 2000-05-01
Abstract: Dans un réseau intelligent permettant de traiter des commandes (44) de réseau intelligent (22), un identificateur (54) d'utilisateur est envoyé au réseau intelligent (22). A la réception de cet identificateur (54) d'utilisateur, une adresse de réseau (56) d'un serveur (48) de réseau intelligent est enregistrée avec un contrôleur (40) de réseau intelligent relié au réseau intelligent (22). Ensuite, en réponse à un déclencheur dans ce réseau intelligent (22), on extrait du serveur (48) de réseau intelligent de l'utilisateur une commande (44) de réseau intelligent (22).
Patent CA-2372950-A1 (CA)
Inventor: ENSIGN THOMAS C JR
IPC: B31D1/02
Filed: 2000-05-04
Abstract: The application discloses an adhesive transfer apparatus (10) comprising a frame (12), a first feed roll (168) carrying a supply of an adhesive transfer substrate (170), and a second feed roll (160) carrying a supply of an adhesive mask substrate (166). The adhesive transfer substrate has a layer of pressure-sensitive adhesive disposed on an adhesive carrying side thereof. The first and second feed rolls are rotatably mounted to the frame. The adhesive mask substrate has a bonding side to which the adhesive will bond. The first and second feed rolls are positioned such that the selected substrate can be inserted between the transfer substrate and the mask substrate. A take-up roll (136) is rotatably mounted to the frame. The adhesive mask substrate has a lead end portion thereof connected to the take-up roll. A pressure applying assembly (125) is constructed and arranged to apply pressure to the transfer substrate and the mask substrate with the selected substrate inserted therebetween. The apparatus being constructed and arranged such that, when the selected substrate is inserted between the adhesive transfer substrate and the adhesive mask substrate, an adhesive transfer operation can be performed wherein (a) the transfer substrate (170), the mask substrate (166), and the selected substrate are moved together in a feeding direction (b) the pressure applying assembly (125) applies pressure to the transfer substrate and the mask substrate with the selected substrate inserted therebetween to cause the adhesive on the adhesive carrying side of the adhesive transfer substrate to adhesively bond to one side of the selected substrate and to any portions of the bonding side of the mask substrate which extend adjacent the periphery of the selected substrate and are engaged directly with the adhesive layer, and (c) the take-up roll (136) rotates to wind up a discharged portion of the mask substrate to which the pressure has been applied along with any portions of the adhesive layer bonded to the bonding side of the discharged portion remaining bonded thereto and being substantially removed from the adhesive carrying side of the transfer substrate.
Patent CA-2373090-A1 (CA)
Inventor: SERRANO LUIZ ANTONIO
IPC: A61F13/02
Filed: 2000-05-09
Abstract: The skin adhesive tape object of the present invention comprises a flexible basic film (10) in one or more layers, with its skin fixation surface incorporating an adhesive coating (20), said adhesive tape consisting of a median portion (B), incorporating two opposite end portions (A, C), at least  one of them having a longitudinal axis (a, c) inclined in relation to the longitudinal axis (b) of the median portion (B).
Patent CA-2375221-A1 (CA)
Title: Label dispensing head for plastic blow molding in-mold labeling system
Inventor: SANFORD EDWARD L
IPC: B65C9/14
Filed: 2000-05-25
Abstract: A dispensing head (36) for an in-mold labeling system includes a lever assembly (106) rotatively driven by a rotary drive member (74) and having a pair of levers (108) that are adjustable with respect to the rotary drive member independently of each other. Each lever (108) has a cam and follower connection (112) to an associated label carrier (38) such that rotation of the rotary drive member (74) provides movement of the label carriers (38) between retracted and label transfer positions.
Patent CA-2375801-A1 (CA)
Title: Printer cartridge with binder
Inventor: KING TOBIN ALLEN
IPC: G06F3/033
Filed: 2000-05-24
Abstract: The invention relates to a cartridge for a digital printer with integral binding means, the cartridge including: a housing defining a plurality of storage areas wherein at least one of the storage areas (631-635) contains colorant for print-ing and at least one of the other storage areas (630) contains material for use by the binding means.
Patent CA-2377606-A1 (CA)
Inventor: KEMPE RON
IPC: B27B25/02
Filed: 2000-06-22
Abstract: A feed wheel (24) for use in a wood working machine (10), in which the feed wheel is rotated while in driving engagement with a wood piece to drive the wood piece past a wood working element. The feed wheel is preferably driveable in one direction only and is freely rotatable in the direction opposite to that for feeding. The feed wheel is preferably formed of a hub part (40) and a rim part (38) which is separable from the hub part. The rim part includes teeth arranged to extend at a helix angle relative to the axis of the wheel and the teeth are preferably provided with a wear-resistant diamond layer for engaging the wood piece.
Patent CA-2378164-A1 (CA)
Inventor: HUDD JENNIFER
IPC: B29B15/08
Filed: 2000-06-29
Abstract: A filled hollow fibre composite material is made by laying up a plurality of prepreg plies (1) of hollow fibre composite material and non-stick film material (2) one on top of another with the non-stick film material (2) interleaving successive plies (1) at selected areas thereof. The laid up interleaved plies are treated to resin bond the ply areas (3) not interleaved with the non-stick film material and leave the interleaved areas (4) unbonded. The so formed laminate is treated at edge regions to expose open unfilled hollow fibre ends (5, 6) and the plies in the unbonded interleaved areas (4) are separated at the non-stick film material (2) to provide access to the open hollow fibre ends (7) in each ply for the introduction of a film material into the hollow fibres through the open hollow fibre ends (7) in one or more of the separated plies (1) to form a filled hollow fibre components material.
Patent CA-2384420-A1 (CA)
Title: Locking joint mechanism
Inventor: MERLO WERNER O
IPC: F16C11/06
Filed: 2002-05-21
Abstract: The locking joint mechanism disclosed in U.S. Pat. No. 5,588,767 is improved by including elements that prevent roll of one joint member relative to another joint member. The roll preventing elements include at least one actuator head or pin spaced from another actuator head or pin end which is received in a concavity defined between adjacent protuberances.  Various protuberance patterns and overall operating mechanisms are also included.
Patent CA-2384626-A1 (CA)
Title: Moteur avec passage direct du reservoir a huile a la pompe a huile
Inventor: BERGMAN DAVID G
IPC: F01M11/02
Filed: 2000-09-05
Abstract: L'invention concerne un moteur comprenant un carter à huile (100) doté d'un tube d'aspiration (140) permettant d'amener l'huile d'un réservoir à huile (105) vers une pompe à huile (130). Un bloc cylindre (110) est relié à un couvercle avant (120) possédant une moitié avant (122) et une moitié arrière (124). Le carter à huile (100) est relié au bloc cylindre (110) et au couvercle avant (120). Le tube d'aspiration (140) est disposé le long du carter à huile (100), et relie le réservoir à huile (105) à un chemin d'entrée (128) formé sur la moitié avant (122). Un téton (150) relie le tube d'aspiration (140) à la partie avant, par introduction dans une ouverture (129) du chemin d'entrée (128). Une garniture (160) est placée adjacente au téton (150), et entre le tube d'aspiration (140) et la partie avant (122). Selon un autre mode de réalisation, il est possible d'éviter l'utilisation du téton (150).
Patent CA-2385061-A1 (CA)
Title: Chair
Inventor: GREGORY PETER GEORGE GORDON
IPC: A47C31/02
Filed: 2000-09-29
Abstract: The invention provides a chair (10) having a seat assembly (12) and a back support assembly (14), the seat assembly (12) including a seat frame (44); sheet material (32) that is stretched and secured in place relative to said frame, the sheet material (32) defining a forward support portion (34) and a  rear support portion (36); wherein the front support portion (34) is of relatively high resistance to resilient deformation and said rear support portion (36) of relatively low resistance to resilient deformation such that  the weight of a person sitting on the chair causes differential deformation of the front and rear support portions whereby the rear support portion is deformed to a greater extent than the forward support portion, the differential deformation of the forward and rear support portions acting to locate the occupants ischial tuberosity behind the forward support portion thereby resisting forward movement of the sitter from the chair and thus retaining the sitter in a correct seating position. The invention also provides for a method of securing a sheet material (32) in a seat frame (44)  to form a support portion (34, 36).
Patent CA-2386557-A1 (CA)
Title: Frame for attachment to a dock structure having means to receive containers
Inventor: BROWN JOHN PHILLIP
IPC: B63B35/34
Filed: 2002-05-15
Abstract: A frame adapted to receive containers, particularly empty plastic bevera ge containers, such as two-liter plastic pop bottles, and adapted to be attache d to a dock structure. When the dock structure, frame and bottles are in mutual cooperation, the containers provide buoyancy to the dock structure. The containers are preferably screwed into the frame and may be removed.
Patent CA-2388538-A1 (CA)
Title: Bacillus thuringiensis toxin active against formicidae (ant)
Inventor: BULLA LEE A JR
IPC: A01N63/50
Filed: 2000-10-25
Abstract: A composition and method for killing fire ants is disclosed that includes th e purified and activated Cry toxin from a novel strain of Bacillus thuringiensis, wherein the water soluble, partially purified, activated toxi n is provided along with an attractant to kill the imported fire and using a biodegradable, environmentally sound glycoprotein without a need for toxic chemicals.
Patent CA-2393563-A1 (CA)
Title: Balle de golf monobloc
Inventor: NESBITT R DENNIS
IPC: C08K5/098
Filed: 2000-12-06
Abstract: L'invention se rapporte à de nouvelles compositions et à des balles de golf fabriquées à partir de ces compositions. Lesdites compositions comportent généralement un mélange réticulé d'un élastomère, d'un agent de polymérisation peroxyde, d'un co-agent et d'un acide polycarboxylique insaturé. Plus particulièrement, la composition réticulée comporte un mélange réticulé de cis 1,4 polybutadiène, de peroxyde de dicumyle, de diacrylate de zinc et d'acide fumarique. Cette composition permet de fabriquer des balles de golfs monoblocs présentant une durabilité améliorée.
Patent CA-2395292-A1 (CA)
Title: Organometal compound catalyst
Inventor: JENSEN MICHAEL D
IPC: C08F4/16
Filed: 2000-12-12
Abstract: This invention provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer. This invention also provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer, wherein said catalyst composition comprises contacting an organometal compound, an organoaluminum compound, and a treated solid oxide compound.
Patent CA-2395927-A1 (CA)
Title: Skin decoration apparatus and method
Inventor: WEBER PAUL J
IPC: A01K11/00
Filed: 2000-04-04
Abstract: The human body is decorated with highly detailed, multicolored, personalized  designs using inkjet or similar printing technology. The designs are applied  to the epidermal and upper dermal skin layers and last for at least several weeks. The decoration is produced by a print head comprising an array of inkjet nozzles, which spray biocompatible inks or dyes onto the skin. The print head and nozzle array may be large enough to cover the entire design area, or the print head can be connected to a scanning mechanism to scan in one, two, or three directions. The decorations can be applied to highly contoured skin surfaces. A computer stores the desired design and controls t he firing of nozzles to produce the desired decoration or tattoo.
Patent CA-2396674-A1 (CA)
Inventor: GROS PHILIPPE
IPC: C12N15/09
Filed: 2000-12-21
Abstract: This invention relates to newly identified polynucleotides and polypeptides, their production and uses, as well as their variants, agonists and antagonists, and their uses. In particular, the invention relates to polynucleotides and polypeptides of a Staphylococcus aureus (S. aureus) DnaI related protein, as well as its variants. Also, the invention relates to a specific interaction between the S. aureus DnaI related protein or specific regions thereof, and a growth-inhibitory protein encoded by the S. aureus bacteriophage 77 genome. The phage protein interacts with amino acids 150 -313 of S. aureus DnaI polypeptide, and the invention relates to the use of this interaction target site as the basis of drug screening assays. In addition, the invention relates to polynu-cleotides and polypeptides of a protein complex containing S. aureus DnaI and DnaC related proteins, as well as their variants.
Patent CA-2400316-A1 (CA)
Inventor: ANDERSON N LEIGH
IPC: G01N27/447
Filed: 2001-02-15
Abstract: An automated computer controlled apparatus includes a robotic assembly for capturing an electrophoresis gel and transferring the gel to a sequence of treatment stages. The robotic assembly has an articulated arm assembly for capturing a gel and moving the gel to a selected work station. The gels are supported by a carrier having magnetically biased clamping jaws. The robotic  arm assembly is constructed to capture the carrier to manipulate the gel. Th e gel is suspended by the carrier in a manner to prevent tearing and stretchin g of the gel. The gel treating stations have tanks with surfaces to inhibit th e gel from adhering to the walls of the tank. Typically, the surfaces of the walls have a plurality of channels formed by projections to allow the flow o f liquid between the gel and the wall surface and reduce surface area of the wall contacting the gel. An agitating assembly reciprocates the gel in the tank to agitate the treating liquid. In one embodiment, an agitating plate moves in a reciprocating manner within the tank and is able to press the gel  against a transparent wall of the tank at selected intervals so that an imag e of the gel can be captured at selected time intervals.
Patent CA-2401501-A1 (CA)
Title: Roller conveying apparatus
Inventor: DONKIN THOMAS G
IPC: B65G13/12
Filed: 2001-02-16
Abstract: A track roller assembly comprises an inner channel member and an outer chann el member, the outer channel member having opposing flanges with a conduit for receiving an air line for operating the assembly. An inflatable air bag is between the inner and outer channel members for raising and lowering the air  bag. The supply air line, which is flexible and compressible, for operating the air bag, is releasably attached externally the channel members in and protected by the conduit by opposing spaced ribs. The supply air line is squeezed between the ribs during insertion into the conduit.
Patent CA-2403118-A1 (CA)
Inventor: HANYA IZUMI
IPC: C12Q1/68
Filed: 2001-02-23
Abstract: L'invention concerne une technique permettant d'identifier de manière rapide et pratique une bactérie toxique résistant aux acides, contaminant des spécimens tels que des boissons. Cette technique consiste à détecter la bactérie résistant aux acides dans un spécimen par PCR, au moyen d'une paire d'amorces constituées d'une combinaison spécifique, sélectionnée parmi les amorces d'acides nucléiques présentant les séquences de base représentées par SEQ ID NO : 1 à 14, puis à l'identifier.
Patent CA-2405050-A1 (CA)
Title: Production of tcr gamma delta t cells
Inventor: SKEA DANNA L
IPC: A61K35/12
Filed: 2001-04-03
Abstract: The method for obtaining and expanding TcR.gamma..delta.+ T cells in culture is described. The method involves: (1) culturing cells from a sample containing TcR.gamma..delta.+ T cells or precursors thereof in a first culture medium comprising a T cell mitogen and at least two growth factors and (2) culturing the cells obtained in step (1) in a second culture medium comprising at least two growth factors. The two growth factors are factors with interleukin-2-like and interleukin-7-like activity. The TcR.gamma..delta.+ T  cells obtained by the method can be used in a variety of experimental, therapeutic and commercial applications.
Patent CA-2405164-A1 (CA)
Inventor: PARSONS J STUART
IPC: A61M5/30
Filed: 2001-04-03
Abstract: A disposable needleless injection device includes an integral unit that is dimensioned and arranged to be grasped in the hand of a user. The system is spring-loaded and is manufactured and shipped with the spring (13) in a pre- cocked condition. An integral ampule (50) is fillable by manipulation of a thrust rod/shaft which extends longitudinally through the device and is able  to be grasped by a user. Once the unit is filled with a selected medication,  it is held proximate the skin in order to inject the selected dosage. The un it is constructed from a maximum of eight component parts and is assembled in a  matter of moments by unskilled personnel.
Patent CA-2405552-A1 (CA)
Title: Respirator cartridge with service life indicator
Inventor: CURADO LEN
IPC: B01D53/06
Filed: 2001-09-12
Abstract: A rotationally adjustable respirator cartridge (10) having a self-contained end of service life indicator (50) adjacent the interior of a sidewall (14) of the cartridge shell (12) and in contact with the filter medium )32) provides a color-changing display field (54) that is visible to the wearer of the respirator through a transparent portion (15)of sidewall (14). Display window (66) is defined by opaque border area (64) that surrounds sensor display field (54) and obscures a predetermined portion of the downstream end of the indicator (50) to provide a desired margin of safety to the wearer.  In order to permit the wearer to rotationally position the color-changing display field (54) in the line of sight through the transparent portion (15) of the respirator facepiece, cartridge (10) is provided with a rotatable mounting assembly that is continuously rotatable in one direction and that forms a seal with the cartridge shell (12).