baber/WOPTO huggingface dataset:
Patent EP-1425280-A2 (EP)
Inventor: DI FABIO ROMANO
IPC: A61K31/4375
Filed: 2002-07-15
Abstract: The present invention provides compounds of formula (I) including stereoisomers, prodrugs and pharmaceutically acceptable salts or solvates thereof   
wherein  R  is aryl or heteroaryl, each of which may be substituted by I to 4 groups selected from: 
halogen, C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo C1-C6 alkoxy, -C(O)R 5 , nitro, -NR 6 R 7 , cyano, and a group R 8 ;  R 1   is hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo C1-C6 alkyl, halo C1-C6 alkoxy, halogen, NR 6 R 7  or cyano;  R 2  and R 3   corresponds to;     R 4   is hydrogen, C1-C6 alkyl, halogen or halo C1-C6 alkyl;  R 5   is a C1-C4 alkyl, -OR 6  or -NR 6 R 7 ;  R 6   is hydrogen or C1-C6 alkyl;  R 7   is hydrogen or C1-C6 alkyl;  R 8   is a 5-6 membered heterocycle, which may be saturated or may contain one to three double bonds, and which may be substituted by 1 or more R 11  groups;  R 11   is C3-C7 cycloalkyl, C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo C1-C6 alkoxy, hydroxy, halogen, nitro, cyano, or C(O)NR 6 R 7 ;  
to processes for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of conditions mediated by corticotropin-releasing factor (CRF).
Patent EP-1439879-A2 (EP)
Title: Breathing mask device and application device and frontal support device thereof
Inventor: LANG BERND
IPC: A61M16/06
Filed: 2002-10-22
Abstract: The invention relates to a breathing mask device for supplying a respiratory gas to a patient. The invention also relates to a frontal support device therefor. The inventive breathing mask device comprises a curved body, a sealing lip device for application on the face area of the user of the mask, a respiratory gas line for the supply of respiratory gas to the interior of the mask which is connected to the opening of the nose and/or mouth of the user of the mask and which is defined by the curved body. The inventive breathing mask device is characterized by an application structure which is used for the application of the sealing lip device together with the curved body. The application structure is provided with a carrier section on which a respiratory gas line element embodied as a docking port is detachably arranged. The inventive frontal support device comprises a support element provided in an application position of the breathing mask for supporting the frontal area of a user of the mask in addition to a holder for holding the support element a tiltable manner. As a result high adaptability is achieved with respect to the most diverse type of facial structures even when the support element is comparatively large.
Patent EP-1468195-A2 (EP)
Inventor: WILSON LARRY J
IPC: F16B39/24
Filed: 2002-09-06
Abstract: The fastener assembly comprises a torquing member and a clamping pressure member assembled together on a common access. The torquing member has annual threads formed around the axis. An annular bearing surface extends around the axis on one end of the member. The clamping pressure member has an annular bearing surface formed around the axis on one end and an annular clamping surface extending around the axis on an opposite end. The annular bearing surface of the torquing member includes a first series of helically inclined surface segments having substantially the same pitch axis as the threads and a second series of helically inclined surface segments having the same pitch axis as the threads but a pitch equal to or greater than that of the threads, with an opposite incline. The annual bearing surface on the clamping pressure member includes a first series of helically inclined surface segments having substantially the same pitch axis as the threads, and a second series of helically inclined surface segments having substantially the same pitch and direction as said equal or greater pitch. Helically inclined bearing surfaces on the torquing member and the clamping pressure member engage each other in locking relationship.
Patent EP-1441653-A2 (EP)
Inventor: HARE BRADLEY A
IPC: A61B17/32
Filed: 2002-10-10
Abstract: An ultrasonic medical device comprising an ultrasonic probe (25) and a collet assembly for probe attachment and detachment, and a method of removing occlusions in blood vessels using the ultrasonic medical device. The probe (25) detachability allows insertion, manipulation and withdrawal independently of a device body. The collet assembly (5) comprises a compression clamp (10) capable of releasably receiving the probe (25), and a compression  housing (14) that initiates a minimal area 'line-contact' between the collet assembly segments upon engagement. A line-contact lip (21) ensures consistent and repeatable contact between the compression clamp (10) and the compression housing (14) at a pre-determined location to  provide a consistent closing force on the probe (25) for any selected tightening torque. The line- contact between the collet assembly segments provides efficient ultrasonic energy transfer from an ultrasonic energy source (30) to the probe (25) thereby increasing probe efficiency during tissue ablation.
Patent EP-1454143-A2 (EP)
Inventor: GUT IVO GLYNNE
IPC: G01N33/68
Filed: 2002-12-12
Abstract: L'invention concerne une méthode permettant d'identifier et/ou de quantifier et/ou de caractériser des protéines dans un mélange de protéines, ces protéines étant superposées en fonction des caractéristiques sur un réseau, et un procédé, de préférence une analyse spectrométrique de masse, étant appliqué sur les protéines en fonction des caractéristiques, ce qui permet de déterminer la nature et la quantité des protéines. Plus particulièrement, cette méthode permet d'effectuer une analyse comparative de la nature et de la quantité de protéines dans au moins deux échantillons. Elle permet également la sélection ciblée de protéines extraites d'un mélange de protéines. Ladite méthode permet aussi d'identifier les structures tridimensionnelles qui interagissent avec une protéine cible sélectionnée ou une modification de ladite protéine.
Patent EP-1435872-A2 (EP)
Title: Procede et appareil de realisation d'une anastamose
Inventor: ROSENGART TODD K
IPC: A61B17/22
Filed: 2002-10-11
Abstract: L'invention concerne des systèmes et procédés de pose de greffes conçus pour réaliser une opération de dérivation cardiaque utilisant un greffon ou une artère mammaire. Pour réaliser ces opérations, on peut utiliser une combinaison de cathéters et de guides à travers l'aorte, l'artère coronaire et la région thoracique.
Patent EP-1399135-A2 (EP)
Inventor: UHLAND SCOTT A
IPC: B23K26/00
Filed: 2002-06-28
Abstract: Devices are provided for the controlled exposure or release of contents stored in hermetically sealed reservoirs. The devices comprise a primary substrate having a front side and a back side, and including one or more hermetic sealing materials; a plurality of reservoirs in the primary substrate positioned between the front side and the back side; reservoir contents, which comprise chemical molecules (such as drugs) or a secondary device (such as a glucose sensor), located inside the reservoirs; a hermetic sealing substrate having a surface composed of one or more hermetic sealing materials; and a hermetic seal formed between and joining the primary substrate and the hermetic sealing substrate, wherein the hermetic seal independently seals the reservoirs.
Patent EP-1336393-A2 (EP)
Inventor: GEIS JOHN S
IPC: A61F2/954
Filed: 2003-02-13
Abstract: The present invention relates to a stent-prosthesis (1), in particular an aortastent-prosthesis,
comprising an essentially cylindrical tube (12) and at least
one spring element (11, 11', 11") for attaching at least a part of the stent-prosthesis
(1) to the inner wall of a blood vessel, wherein the tube (12) is
made of flexible material, having a proximal end (121) and having at least a
first and a second section (2, 3) being axially adjacent to each other, wherein
in the first section (3) of the tube (12) at least one of said spring elements
(11, 11', 11") is provided and the the second section (2), adjacent to the first
section (3), being free of spring elements (11, 11', 11") and only being
formed by the flexible material of the tube (12) and wherein the second
- section (2) extends to the proximal end (121) of the tube (12), and wherein
the at least one spring element (11, 11, 11") can be compressed in the radial
direction of the tube (12) and in the relaxed state keeps the tube (12) at least
over the first section (3), in which it is provided, in an open state. The
invention further relates to a delivery device for such a vessel support, in
particular a catheter system, and to a delivery set.
Patent EP-1357436-A2 (EP)
Inventor: OGAKI HARUNOBU
IPC: C08J7/046
Filed: 2003-04-24
Abstract: The present invention relates to an
electrophotographic photosensitive member having a
support and provided thereon a photosensitive layer.
The photosensitive layer contains a high-molecular
weight charge-transporting material having a specific
repeating structural unit. The high-molecular weight
charge-transporting material has a weight-average
molecular weight Mw of 1,500 or more and an energy
level of highest occupied molecular orbital, E HOMO , of
from -8.3 eV or more to -8.0 eV or less as found by
semiempirical molecular-orbital calculation. The
present invention also relates to a process cartridge
and an electrophotographic apparatus which have such
an electrophotographic photosensitive member.
Patent EP-1365358-A2 (EP)
Inventor: ASANO TAKEO
IPC: H04W4/00
Filed: 2003-05-21
Abstract: A plurality of known markers (14) is disposed in a
specific district which is an object of the present
system. A marker detection section (2) detects the
known markers existing in the image photographed by an
image pickup device (1; 11A). A position/orientation
relation calculation section (3) identifies the known
marker detected by the marker detection section to
calculate position and orientation relations between
the identified known marker and the image pickup
device. An associated information obtaining section
(4) obtains predetermined information associated with
the known marker identified by the position/orientation
relation calculation section. An information
processing section (5) processes the predetermined
information obtained by the associated information
obtaining section based on the position and orientation
relations calculated by the position/orientation
relation calculation section. A display device (6;
11B) superimposes and displays the information
processed by the information processing section on the
image photographed by the image pickup device. At
least the image pickup device and display device are
disposed in a portable information terminal (1), and
the other sections are disposed in a server (12) which
can perform radio communication with the portable
information terminal.
Patent EP-1382585-A2 (EP)
Inventor: NANNINI MAURIZIO
IPC: C04B33/132
Filed: 2003-05-19
Abstract: Transformation method for products containing asbestos, comprising
several working steps, such as grinding, adding components like
calcined alumina, clay and material giving porosity, sintering.
Patent EP-1433676-A2 (EP)
Title: Sensing device for detecting moisture on a transparent glass pane
Inventor: SCHMITT PATRICK
IPC: G01N21/55
Filed: 2003-05-30
Abstract: The arrangement has at least one radiation transmitter (31) and at least one radiation receiver (32) in a housing (10,20), a refractive radiation guidance arrangement (21,22) that couples radiation from the transmitter into the screen and feeds part of the radiation to the receiver depending on the wetting of the screen. A reflective radiation guide arrangement feeds radiation not directly captured by the refractive arrangement to it indirectly.
Patent EP-1389726-A2 (EP)
Inventor: SCHOENENBACH HEINRICH R
IPC: A45C11/24
Filed: 2003-08-02
Abstract: The device is in the form of a standard luggage item, e.g. a luggage bag or a suitcase, provided with a first compartment for receiving luggage, e.g. clothing and a second compartment (18) for receiving the rifle (28a,28b), both compartments contained within the contour of the luggage item and separated from one another via a partition wall. The rifle compartment is sized for reception of a weapon case (25) and is fully enclosed by the partition wall with the exception of a separate access opening (16) which is sealed via a cover element (19).
Patent EP-1419751-A2 (EP)
Title: Disposable excrement collecting bag
Inventor: NAKAMURA EIZOU
IPC: A61F5/44
Filed: 2003-08-04
Abstract: There is provided a disposable toilet bowl for care which can be worn without
a sense of incongruity substantially all time by a serious person requiring care, and in
which discharged excrements are not leaked and adhered to portions other than the
circumference of the anus. 
     The disposable toilet bowl for care comprises: a rod-like anus application
member (3) which fits into a groove (20) between the buttocks (19) around a person's anus
(17) and is filled with a fluid; an excrements passage hole which is provided so as to
extend through the center of the anus application member (3) and one end of which is
applied to the anus (17) when the anus application member (3) is fitted into the groove (20)
between the buttocks (19); a flexible sheet-like pad (8) which supports the anus
application member (3) from the bottom thereof; fixing means provided on the pad (8) for
holding the state that said anus application member (3) is fitted into the groove (20)
between the buttocks (19); and a bag body (15) which is communicated with the
excrements passage hole, of which upper end edge is fixed around the central hole
of the pad (8), and which receives internally the excrements discharged from the
person's anus (17) through the excrements passage hole and the hole of the pad (8).
Patent EP-1467465-A2 (EP)
Inventor: KANTER MICHAEL
IPC: H05B37/03
Filed: 2003-11-29
Abstract: The method involves monitoring the emergency lighting (3,4) in a tunnel with a controller of a tunnel safety lighting system consisting of a tunnel monitoring center (1) and emergency lighting equipment (2), which can operate autonomously at least for a time and that is connected via a communications line to a remote actuation system, detecting possible faults, securely recording them and initiating correction. An independent claim is also included for the following: (a) an arrangement for safe emergency tunnel lighting.
Patent EP-1334790-A2 (EP)
Inventor: BLEEKER DERK JAN
IPC: B28D1/04
Filed: 2003-02-10
Abstract: The invention relates to a sawing arrangement for sawing
material like for example concrete, stone or asphalt. In
the saw blade (4), a ring of holes (11,25) and a number of
channels (13,26) is made, which channels (13,26) end near
cutting faces of the saw blade (4). With the aid of cup-shaped
elements (20a,20b,23), mounted close to the saw
blade (4), the liquid is supplied to the holes (11,25).
Patent EP-1353027-A2 (EP)
Inventor: LACONTE RICH
IPC: B64D45/00
Filed: 2003-03-31
Abstract: A dead bolt lock apparatus specifically adapted for use with a flight
deck door of an aircraft. The apparatus includes a dead bolt member which
can be moved between locked and unlocked positions via a key. A lockout
handle is included on the side of the apparatus which faces the flight deck
area of the aircraft. The lockout handle is movable rotationally from a first
position, wherein it has no affect on the use of the key to unlock the dead bolt,
to a second position wherein it prevents the dead bolt from being moved out
of a locked position by use of the key. The apparatus thus provides an
additional degree of security to occupants of the flight deck by allowing them
to prevent unlocking of the apparatus even with the key.
Patent EP-1356966-A2 (EP)
Inventor: WANG MINGYU
IPC: B60H1/32
Filed: 2003-04-02
Abstract: An improved motor vehicle automatic climate control methodology
develops HVAC commands for transient phase operation independent of the
HVAC commands calibrated for steady-state phase operation. At system
activation, a transient phase indicator is initialized based on the cabin
temperature and the set temperature, and thereafter updated to reflect progress
toward steady-state phase operation (18). The steady-state HVAC commands
are based on ambient conditions and the set temperature (14, 16), and the
HVAC commands at system activation are based on the steady-state commands
and offsets based on the initial in-car temperature (12, 16, 22, 24, 26). A
transient modifier based on the transient phase indicator brings the initial
HVAC commands into correspondence with the steady-state HVAC commands
as the cabin temperature approaches the set temperature (22, 24, 26). The
transient modifier can be an exponential function of the transient phase
indicator, and the HVAC commands can be clamped at the initial values until
the transient phase indicator reflects a predetermined amount of progress toward
the steady-state phase (22).
Patent EP-1371963-A2 (EP)
Inventor: MAYRHOFER HANS
IPC: G01N30/88
Filed: 2003-06-12
Abstract: The valve control system, for extraction of gas or fluid samples, has a step motor and a control, where the motor rotor is connected to a rotating unit at the valve assembly, to give a selective link between the various inflows and outflows. A coupling transmits a constant rotor speed to the rotating unit, and the control allows a rotation increment at the rotating unit. The valve control system, to extract gas or fluid samples from flow channels for analysis, has a step motor (1) and a control, where the motor rotor (5) is connected to a rotating unit (3) at the valve assembly (4), to be turned by a given angle to give a selective link between the various inflows and outflows. A coupling (2) transmits a constant rotor speed to the rotating unit, and the control allows a rotation increment at the rotating unit which is smaller than the switching angle for positioning.
Patent EP-1332912-A2 (EP)
Inventor: ENJOJI NAOYUKI
IPC: B60K1/04
Filed: 2003-02-05
Abstract: A fuel cell system (32) incorporated in a vehicle (30) has a main electric motor (15), a drive power transmitting mechanism (38) for engaging and disengaging a fuel gas pump (6), a coolant fluid pump (9), a supercharger (12), and a compressor (19), which serve as auxiliary equipment, and transmitting a drive power to the auxiliary equipment, and an auxiliary electric motor (40) coaxially connectable to the main electric motor (15) for transmitting a drive power to the auxiliary equipment depending on the manner in which the vehicle (30) is operated.
Patent EP-1344961-A2 (EP)
Inventor: TSUJII YOSHITOMO
IPC: F16G13/04
Filed: 2003-03-11
Abstract: A silent chain having improved wear resistance comprising link plates (2) that have a
pair of pin holes (22) that are finished using a punch with a round edge portion, and connecting
pins with a carbide layer formed on a the base material of the pin. The carbide layer
includes vanadium carbide as the principal component and chromium carbide as the
secondary component. The carbide layer is formed on the outermost surface of the base
material. A boundary layer is formed in the boundary region between the carbide layer
and the base material. The boundary layer includes vanadium carbide whose percentage
content decreases sharply and chromium carbide whose percentage content increases
sharply. Since the carbide layer formed on top of the base metal consists principally of
vanadium carbide it is possible to prevent peeling from the surface of the carbide layer.
Patent EP-1357479-A2 (EP)
Inventor: SUZUKI KOUICHI
IPC: H04L69/40
Filed: 2003-04-16
Abstract: A data transfer system is provided for preventing a slave device
from operating erroneously or running out of control on resuming
communication after communication is interrupted due to the occurrence
of abnormal circumstances such as a power failure and the like, wherein a
master device transmits a stop condition to the slave device for
terminating communication and performs a power failure-processing task
when abnormal circumstances such as a power failure or a momentary
power failure occurs, and transmits a start condition for reestablishing
communication after transmitting a stop condition to the slave device, and
the slave device terminates communication on receipt of either stop
condition and reestablishes communication on receipt of a start condition.
Patent EP-1398485-A2 (EP)
Inventor: HERMANN J BREITBACH
IPC: G01M15/10
Filed: 2003-09-12
Abstract: A method for controlling the concentration of one or more constituents of an exhaust flow
from a combustion device (10), the method comprising providing a measuring cell (13)
and passing at least a sample of the exhaust flow through the cell (13); transmitting infra
red radiation at a reference wavelength through the measuring cell and measuring a
reference intensity which is representative of the intensity of radiation transmitted through
the cell (13) at the reference wavelength. Infra red radiation, at one or more measurement
wavelength, is transmitted through the measuring cell (13) and a measurement intensity is
measured which is representative of the intensity of radiation transmitted through the cell
at the or each measurement wavelength. The reference intensity is compared with the or
each measurement intensity to deduce a concentration value for one or more constituents
of the exhaust and one or more control parameters of the combustion device (10) is varied
in response to the or each concentration value, thereby to optimise the concentration of the
or each constituent of the exhaust flow.
Patent EP-1519784-A2 (EP)
Inventor: KRUEGER CHARLES W
IPC: B01J37/03
Filed: 2003-03-12
Abstract: Cette invention concerne un réacteur/purificateur produisant de l'hydrogène pur dans une pile ou un ensemble de paires de chambres de réaction haute et basse pression reliées alternativement les unes aux autres. Une structure écran poreuse aux gaz et favorisant les turbulences, recouverte d'un catalyseur de reformage à la vapeur, est intercalée entre une membrane plane en alliage de palladium à sélectivité pour l'hydrogène et une plaque métallique imperméable aux gaz et conductrice de chaleur à l'intérieur de chacune des chambres de réaction haute pression. En réagissant avec de la vapeur et un combustible d'hydrocarbure tel que du méthane ou un gaz de synthèse, et/ou du monoxyde de carbone, sous une température convenablement contrôlée entre 200 et 650 °C environ, la structure à revêtement catalytique produit de l'hydrogène et des oxydes de carbone dans une plage de température isotherme dans chacun des chambres de réaction haute pression tout en laissant simultanément passer de l'hydrogène pur au travers de la membrane dans la chambre de réaction correspondante à laquelle elle est connectée, le transfert thermique en direction et en provenance due catalyseur se produisant in situ surtout par conduction au travers de la plaque métallique correspondante.
Patent EP-1495141-A2 (EP)
Inventor: BERESFORD PAUL J
IPC: A61K38/00
Filed: 2003-03-20
Abstract: L'invention concerne des procédés et des compositions d'ARNsi destinés à inhiber le VIH et/ou sa réplication, des systèmes d'identification d'ARNsi efficaces permettant d'inhiber le VIH et des systèmes d'étude des mécanismes de l'infection par le VIH. L'invention concerne aussi des procédés et des compositions destinés à inhiber l'infection, la pathogénicité et/ou la réplication d'un agent infectieux, par l'utilisation, par exemple, d'ARNsi afin d'inhiber l'expression génétique de cellule hôte.
Patent EP-1502386-A2 (EP)
Inventor: COTTE PIERRE-ALAIN
IPC: H04L12/58
Filed: 2003-04-30
Abstract: L'invention concerne un environnement de communications, qui comprend une première unité d'utilisateur final configurée pour assurer des communications en réseau; et un site web correspondant à une entité spécifique. Le site web assure, une fois que l'on y a accédé, des communications privées entre ladite première unité d'utilisateur final et l'entité spécifique.