baber/WOPTO huggingface dataset:
Patent EP-3293274-A2 (EP)
Inventor: VANDER HORN PETER
IPC: C12N9/12
Filed: 2012-08-10
Abstract: The present disclosure provides compositions, methods, kits, systems and apparatus that are useful for nucleic acid polymerization. In particular, modified polymerases and biologically active fragment thereof are provided that allow for nucleic acid amplification. In one aspect, the disclosure relates to modified polymerases useful for nucleic acid sequencing, genotyping, copy number variation analysis, paired-end sequencing and other forms of genetic analysis. In some aspects, the disclosure relates to modified polymerases useful for the generation of nucleic acid libraries or nucleic acid templates for use in various downstream processes. In some aspects, the disclosure relates to the identification of homologous amino acid mutations that can be transferred across classes or families of polymerases to provide novel polymerases with altered catalytic properties. In some aspects, the disclosure provides modified polymerases having enhanced catalytic properties as compared to a reference polymerase.
Patent EP-3532987-A2 (EP)
Inventor: WEXLER YONATAN
IPC: G06K9/00
Filed: 2017-10-25
Abstract: The present disclosure relates to systems and methods for selecting an action based on a detected person. In one implementation, a wearable apparatus may include a wearable image sensor configured to capture a plurality of images from the environment of the user of the wearable apparatus and at least one processing device. The at least one processing device may be programmed to analyze at least one of the plurality of images to detect the person; analyze at least one of the plurality of images to identify an attribute of the detected person; select at least one category for the detected person based on the identified attribute; select at least one action based on the at least one category; and cause the at least one selected action to be executed.
Patent EP-3474884-A2 (EP)
Title: Compositions et méthodes permettant de moduler les propriétés immunostimulantes et anti-inflammatoires de l'il-10
Inventor: MOUSTAKAS DEMETRI T
IPC: A61K38/20
Filed: 2017-06-22
Abstract: L'invention concerne des compositions et des méthodes permettant de moduler les propriétés immunostimulantes et/ou les propriétés anti-inflammatoires de l'IL-10. La présente invention concerne des polypeptides scIL-10 de formule 1. Les polypeptides selon l'invention sont éventuellement liés à un partenaire de fusion.
Patent EP-3548957-A2 (EP)
Inventor: CHOI SUNGHWAN
IPC: G02B27/01
Filed: 2017-05-11
Abstract: The present invention relates to a head-up display for a vehicle configured to change display positions of a plurality of virtual images displayed through a windshield of the vehicle or the like to implement augmented reality and a control method thereof, and a head-up display for a vehicle according to an embodiment of the present disclosure may include a mirror unit comprising a first mirror for reflecting first and second image lights toward a windshield of the vehicle; a display layer located at the windshield of the vehicle to display a first virtual image corresponding to the first image light in a first region, and display a second virtual image corresponding to the second image light in a second region; and a controller configured to change an inclination of the first mirror to change a display position of the first and the second virtual image.
Patent EP-3360895-A2 (EP)
Inventor: KANNICHT CHRISTOPH
IPC: C07K14/755
Filed: 2015-06-08
Abstract: A composition comprising a complex of Factor VIII and one or more Von Willebrand Factor peptides, wherein the Von Willebrand Factor peptides comprise at least the amino acids 764 to 1035 and 1691 to 1905 of SEQ ID No. 1 but not amino acids 2255 to 2645 of SEQ ID No. 1.
Patent EP-3569704-A2 (EP)
Inventor: NIU CANFANG
IPC: C12R1/19
Filed: 2018-01-15
Abstract: The present invention relates to the field of genetic engineering, particularly to phytase variants YkAPPA having amino acid sequence substituting Leucine at the 162 th  site of the sequence set forth in SEQ ID NO.1 with glycine or proline, or having amino acid sequence substituting glutamic acid at the 230 th  site of the sequence set forth in SEQ ID NO.1 with glycine, alanine, serine, threonine, aspartic acid, proline, or arginine, and having improved pepsin resistance and increased catalytic efficiency of 2.1 times of that of the wild phytase, in the benefit of the development of economical feed enzyme industry.
Patent EP-3654949-A2 (EP)
Inventor: LÓPEZ-GOERNE TESSY MARÍA
IPC: A61K31/282
Filed: 2018-07-18
Abstract: Nanostructured and biocompatible biocatalysts an organic ligand either linear or branched to Pt, Cu, or Fe-based compounds, in II, III or IV oxidation state, having cytotoxic activity for use in the treatment of cancer in animals or humans.
Patent EP-3823591-A2 (EP)
Title: Insuline humaine injectable micronisée
Inventor: CELIK DEVRIM
IPC: A61K38/28
Filed: 2019-07-11
Abstract: La présente invention concerne l'insuline humaine injectable micronisée pour le traitement des diabète de types I et II du chez les mammifères, en particulier chez l'humain.
Patent EP-3702776-A2 (EP)
Inventor: KEY ADAM
IPC: G01N33/18
Filed: 2020-02-26
Abstract: A water quality monitor system (100, 200) comprising a base (102, 202) having a first end and a second end is disclosed. A cover (112, 212) is removably coupled to the first end of the base such that the cover surrounds and covers the first end of the base. A flow cell (104, 204) jar is connected to the second end of the base. A sensor probe (106, 206) is connected to the second end of the base and extends downward into the flow cell jar. The sensor probe is configured to measure a plurality of water quality parameters. The base further includes an inlet (108, 208) and an outlet (110, 210) connected to opposing ends of the base and connected in-line to the plumbing of a swimming pool recirculation system. A controller is configured to provide a connection between the water quality monitor and a cloud-based storage system, using a wireless network. The measured water quality parameters are transmitted through the wireless network to the cloud storage system.
Patent EP-3817061-A2 (EP)
Inventor: JU SUNG BAE
IPC: H05B44/00
Filed: 2020-09-24
Abstract: A display device includes a substrate in which a cut-out portion is defined, and a first conductive layer disposed on the substrate and including a first signal line and a first test line, where the first test line crosses the cut-out portion, and one end portion of the first test line includes a first pad region that is expanded.
Patent EP-3986921-A2 (EP)
Inventor: VILSTRUP JOACHIM POLD
IPC: C07K14/705
Filed: 2020-06-22
Abstract: The present invention relates to a SorCS2 crystal structure, the atomic coordinates obtained by X-ray crystallography of same, and their use in molecular modelling. The invention further relates to methods of growing crystals of SorCS2. Furthermore, the invention relates to peptides capable of binding to SorCS2, as well as their use as medicament, for example in the treatment of frontotemporal dementia.
Patent EP-4041184-A2 (EP)
Title: Peptide based cosmetic or dermatological treatment of the skin and its appendages
Inventor: MONDON PHILIPPE
IPC: A61K8/81
Filed: 2020-10-06
Abstract: The treatment according to the invention provides the use of at least one peptide having the general Formula X-(Xaa)nK*TTK*X'aa-(Xaa)m-Z for a non-therapeutic cosmetic treatment of keratinous tissues of the skin and of its appendages. In the Formula, K* is selected from lysine, hydroxylysine, ornithine, diaminobutyric acid or diaminopropionic acid or their formylated, acetylated, trifluoroacetylated, methanesulfonylaed or succinylated derivatives, both K* being identical or different; (Xaa) n  and (Xaa) m  correspond independently of one another to a sequence of n or m amino acids Xaa selected independently of one another from Gly, Ala, Pro, Val, Leu, Ile and Phe, with n and m being integers which can be equal or different and comprised between 0 and 5; X'aa is selected from threonine and serine; At the N-terminal end X is selected from H, -CO-R 1 , -SO 2 -R 1  or a biotinoyle group; At the C-terminal end Z is selected from OH, OR 1 , NH 2 , NHR 1  or NR 1 R 2 ; and R 1 and R 2  being, independently of one another, selected from an alkyl, aryl, aralkyl, alkylaryl, alkoxy, saccharide and aryloxy group, which can be linear, branched, cyclic, polycyclic, unsaturated, hydroxylated, carbonylated, phosphorylated and/or sulfurated, said group having from 1 to 24 carbon atoms and the possibility of having in its backbone one or more O, S and/or N heteroatoms. A preferred peptide is the Pal-KTTKS.
Patent EP-4009831-A2 (EP)
Inventor: ZUCKER BOAZ
IPC: A45D27/06
Filed: 2020-08-05
Abstract: An aspect of the invention discloses a system for making lather in a cup, comprising a cup comprising an impeller and a heater in said cup and a base for said cup having a power source configured to provide power to said impeller and to said heater.
Patent EP-4031860-A2 (EP)
Inventor: YANG LAN
IPC: G01N29/12
Filed: 2020-09-18
Abstract: Optical whispering gallery mode (WGM) resonator-based acoustic sensors, imaging systems that make use of the acoustic sensors, and methods of detecting ultrasound waves using the acoustic sensors are disclosed.
Patent EP-4058143-A2 (EP)
Inventor: BEIM PIRAYE YURTTAS
IPC: A61P15/08
Filed: 2020-11-13
Abstract: Provided herein are methods and compositions relating to modified proteins of Anti- Müllerian hormone (AMH) for regulating folliculogenesis in a woman, and in particular regulating follicle activation and maturation and immature (primordial) follicle depletion. In certain embodiments, regulating or inhibiting folliculogenesis in a woman treats ovarian senescence, pauses or slows down ovarian aging and/or delays the onset of menopause and/or the symptoms related to menopause, premature ovarian decline induced by gonadotoxic treatment, or diseases or conditions caused by genetic mutations in genes regulating folliculogenesis and ovarian biology.
Patent EP-3907755-A2 (EP)
Inventor: JEZEWSKI CHRISTOPHER J
IPC: H01L21/768
Filed: 2015-02-21
Abstract: An embodiment includes a metal interconnect structure, comprising: a dielectric layer disposed on a substrate; an opening in the dielectric layer, wherein the opening has sidewalls and exposes a conductive region of at least one of the substrate and an interconnect line; an adhesive layer, comprising manganese, disposed over the conductive region and on the sidewalls; and a fill material, comprising cobalt, within the opening and on a surface of the adhesion layer. Other embodiments are described herein.
Patent EP-3943302-A2 (EP)
Inventor: LIN HUNG-PIN
IPC: B32B38/18
Filed: 2021-05-21
Abstract: An attaching device (100) and a complex-surface attaching intermediary (6) are provided. The complex-surface attaching intermediary (6) includes a frame (61), a buffering assembly (63) movably assembled to the frame (61), and a flexible sheet (62) that is assembled to the frame (61) and the buffering assembly (63). The flexible sheet (62) includes a bonding region (621), a first fixing region (622), and a second fixing region (623), the latter two of which are respectively located at two opposite sides of the bonding region (621). The first fixing region (622) is fixed to the buffering assembly (63). The second fixing region (623) is fixed to the frame (61). When the flexible sheet (62) is compressed to increase a tension value thereof to reach a predetermined starting value, the first fixing region (622) is moved toward the bonding region (621) by an amount of displacement through the buffering assembly (63).
Patent EP-4128768-A2 (EP)
Title: Video data encoding and decoding
Inventor: SHARMAN KARL JAMES
IPC: H04N19/176
Filed: 2021-03-12
Abstract: A video data encoding method for encoding an array of video data values comprises the steps of: frequency-transforming the video data values according to a frequency transform, to generate an array of frequency-transformed values by a matrix-multiplication process using a transform matrix having a data precision of fourteen bits, the frequency transform being a discrete cosine transform; defining a 64 x 64 transform matrix M 64  for a 64 x 64 DCT transform, the matrix M 64  being defined by the accompanying Figures 10a- 10e and 11; for an N x N transform where N is 2, 4, 8 or 16, subsampling the 64 x 64 transform matrix Me4 to select a subset of N x N values, the subset Μ Ν [x][y] of values being defined by:  M 
   N   [x][y] =  M 
   64   [x][( 2 
   6-log2(N)   
 ) )y] for  x, y  = 0..( N - 1).
Patent EP-4251445-A2 (EP)
Inventor: ALI SYED ASAD
IPC: B60G17/0165
Filed: 2021-11-26
Abstract: A control system (300) for controlling an active suspension system (104) of a vehicle (100), the control system comprising one or more controller (301), wherein the control system is configured to: detect (1004) a ramp (202) approached by an overhang of the vehicle; and in dependence on detecting the ramp, control (1020) the active suspension system to modify a relative ride height between a leading ride height at a set of leading wheels (FL, FR) of the vehicle and a trailing ride height at a set of trailing wheels (RL, RR) of the vehicle, to increase a ramp angle (α, β) of the vehicle relative to the ramp.
Patent EP-4256606-A2 (EP)
Title: Donor substrate for the transfer of a thin layer and associated transfer method
Inventor: LARREY VINCENT
IPC: H01L21/762
Filed: 2021-11-19
Abstract: The invention relates to a donor substrate (100) for the transfer of a thin single-crystal layer (1) made of a first material to a receiver substrate (2), the donor substrate (100) having a front side (100a) and a back side (100b), and comprising: - a buried weakened plane (30) which delineates an upper portion (101) from a lower portion (102) of the donor substrate (100); - in the upper portion (101), a first layer (10) on the side of the front side (100a), a second layer (20) adjacent to the buried weakened plane (30), and a stop layer (15) inserted between the first layer (10) and the second layer (20), the first layer (10) being composed of the first material, the stop layer (15) being formed of a second material that allows selective etching with respect to the first material to be achieved; - an amorphized sub-portion (101',101'',101'''), made amorphous through ion implantation, having a thickness strictly lower than that of the upper portion (101), and including at least the first layer (10); the second layer (20) comprising at least one single-crystal sub-layer (22), adjacent to the buried weakened plane (30). The invention also relates to two modes of implementation of a method for transferring a thin single-crystal layer (1) from the donor substrate (100).
Patent EP-4243933-A2 (EP)
Inventor: LEE SE-JIN
IPC: A61P21/06
Filed: 2021-11-12
Abstract: Provided herein are methods of inhibiting type 1 receptor and/or type 2 receptor signaling in subjects, optionally subjects with diseases associated with myostatin, type 1 receptor, and/or type 2 receptor signaling, or muscle loss and/or bone deterioration. Also provided are compositions for inhibition of type 1 receptor and/or type 2 receptor signaling.
Patent EP-4247966-A2 (EP)
Inventor: IAFRATE A JOHN
IPC: C12Q1/68
Filed: 2021-11-19
Abstract: Des procédés basés sur le séquençage de dernière génération (NGS) utilisent des enzymes de restriction sensibles à la méthylation (MSRE) pour l'analyse de méthylation de l'ADN, par exemple, l'ADN tumoral circulant.
Patent EP-4145953-A2 (EP)
Inventor: DEES WALTER
IPC: H04W4/80
Filed: 2019-01-24
Abstract: A wireless device (S) includes a radio (R) for communicating via a wireless communication protocol which employs messages constructed as layer 2 MAC frames each including a layer 2 MAC header and a payload. The wireless device is configured to operate in (i) a first mode in which the wireless device transmits messages (N0, ..., Nn) via the radio each including an IPv6 packet header and an upper layer protocol data unit encapsulated within the payload of a layer 2 MAC frame, and (ii) a second mode in which the wireless device transmits messages (M0, ... , Mn) via the radio each including an upper layer protocol data unit encapsulated within the payload of a layer 2 MAC frame without including the IPv6 header. A relay device (T) comprises a radio for communicating via the wireless communication protocol which employs messages constructed as layer 2 MAC frames each including a layer 2 MAC header and a payload. In one power-saving aspect, the relay device is configured to perform a header insertion service (I) in which the relay device receives messages (M0, ..., Mn) via its radio from the wireless device (S), each including an upper layer protocol data unit encapsulated within the payload of a layer 2 MAC frame without including the IPv6 header. The header insertion service inserts header information (A') into the messages (M0, ..., Mn) received from the wireless device (S) and retransmits the messages with complete headers as messages (M0 ', ..., Mn '). In another power-saving aspect, the relay device additionally or alternatively applies an acknowledgement detection criterion to filter out acknowledgements received from the server, and forwards the filtered out acknowledgements to the wireless device (S) via the radio at a reduced rate.
Patent EP-4218926-A2 (EP)
Inventor: PATIL RAJKUMAR V
IPC: A61P29/00
Filed: 2020-07-29
Abstract: The present disclosure relates to, among other things, compositions and methods for treating pain such as neuropathic pain, ocular pain, chronic pain, pain resulting from chemotherapy or radiation, and pain resulting from nerve injury or nerve degener-ation. In some embodiments, the pain can be resulting from an inflanunatory condition, dysesthesia, or allodynia. The present disclo-sure also relates to methods for treating an inflammatory condition such as ocular inflammation, retinal inflammation, dry eye, uveitis, allergic conjunctivitis, and inflanunation resulting from nerve injury or nerve degeneration.
Patent EP-4204885-A2 (EP)
Inventor: COHEN NOY
IPC: G02B13/02
Filed: 2022-06-07
Abstract: Systems comprising a Wide / Ultra-Wide camera, a folded Tele camera comprising an optical path folding element and a Tele lens module, a lens actuator for moving the Tele lens module for focusing to object-lens distances between 3.0cm and 35cm with an object-to-image magnification between 1:5 and 25:1, and an application processor (AP), wherein the AP is configured to analyze image data from the UW camera to define a Tele capture strategy for a sequence of Macro images with a focal plane slightly shifted from one captured Macro image to another and to generate a new Macro image from this sequence, and wherein the focal plane and a depth of field of the new Macro image can be controlled continuously.
Patent EP-4235165-A2 (EP)
Title: Metal-enzyme sandwich layers
Inventor: ADALIAN DVIN
IPC: G01N27/327
Filed: 2018-11-30
Abstract: Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.
Patent EP-4242673-A2 (EP)
Inventor: ZHANG SHENGJIE
IPC: G01R31/00
Filed: 2017-04-14
Abstract: This application provides a noise generation circuit, a self-checking circuit, an AFCI, and a photovoltaic power generation system. The noise generation circuit includes a power switch module, a noise generator, and a capacitor, where the noise generator is connected to both the power switch module and the capacitor; the power switch module is configured to control, according to a self-checking instruction, whether the noise generator generates a noise signal; and the capacitor is configured to filter out a direct current component in the noise signal when the noise generator generates the noise signal. According to the noise generation circuit, the self-checking circuit, the AFCI, and the photovoltaic power generation system that are provided in this application, no noise signal is generated in a non self-checking time, so that no impact is imposed on a component in the AFCI in a working state or a component in a photovoltaic inverter of the AFCI, thereby ensuring normal working of the AFCI and the photovoltaic inverter.
Patent EP-4249604-A2 (EP)
Title: Compositions and methods of rna analysis
Inventor: CREDLE JOEL
IPC: C12Q1/6806
Filed: 2016-07-22
Abstract: The present disclosure relates to compositions and methods of RNA analysis. In particular, the present disclosure provides a method of RNA analysis that includes obtaining a sample, applying one or more multi-partite probes to the sample, where each of the one or more multi-partite probes includes at least two sub-probes, annealing at least one of the applied one or more multi-partite probes to at least one target nucleic acid within the sample, and ligating the at least two sub-probes associated with the at least one annealed multi-partite probe to create a target nucleic acid proxy that can be detected.
Patent EP-4235436-A2 (EP)
Inventor: AMBICHL ERNST
IPC: G06F11/34
Filed: 2019-08-02
Abstract: The disclosure relates to a computer-implemented method for monitoring performance in a distributed computing environment. Further, a computer-implemented system for monitoring performance in a distributed computing environment is provided. The disclosed technology is directed to a focused and directed identification of causal dependencies between identified and localized abnormal operating conditions on a monitored system comprising in software and hardware components. A heterogeneous set of monitoring agents is deployed to components of the monitored system that provide monitoring data describing the operating conditions of monitored components.
Patent EP-4234836-A2 (EP)
Inventor: LONCKE FRANK
IPC: E04F15/04
Filed: 2016-06-22
Abstract: Floor panel with a substrate (8) and a provided thereon decorative layer (6) of wood veneer (7) having a thickness (T1) of 1 millimeter or less, characterized in that said substrate (8) has an average density of more than 750 kilograms per cubic meter and that said decorative layer (6) is provided on the substrate (8) by means of a layer on the basis of thermosetting resin (9) situated between the substrate (8) and the decorative layer (6). The invention also relates to a method for manufacturing such floor panels (1), wherein a structured veneer surface can be obtained.
Patent EP-4242193-A2 (EP)
Inventor: SHE YING
IPC: C04B35/80
Filed: 2018-08-28
Abstract: A method for fabricating a component (20) includes the steps of depositing a stoichiometric precursor layer (32) onto a preform (26), and densifying the preform (32) by depositing a matrix material (24) onto the stoichiometric precursor layer (32).
Patent EP-4254850-A2 (EP)
Inventor: ZHAO ZHENSHAN
IPC: H04L5/00
Filed: 2020-08-28
Abstract: A user equipment and a method of resource transmission are provided. The method includes determining that physical sidelink feedback channel (PSFCH) resources for a resource pool are divided into M times N PSFCH resource sets in a frequency domain, each PSFCH resource set corresponds to a subchannel in a slot for the resource pool, and N is a number of physical sidelink shared channel (PSSCH) slots associated with a PSFCH slot, M is a number of subchannels for the resource pool, M and N are integers equal to or larger than 1. This can have enough resource for PSFCH transmission between multiple RX UEs, select resource of PSFCH per RX UE within an available transmission resource set, provide a good communication performance, and/or provide high reliability.