baber/WOPTO huggingface dataset:
Patent HK-1133910-A1 (HK)
Title: Anchor for handling building elements, in particular a concrete panel
Inventor: ARTEON MARCEL
IPC: E04G/
Filed: 2010-01-26
Abstract: A handling anchor, for lifting, raising, turning over, transporting, and laying building elements, such as precast blocks or panels, essentially made of concrete and to be connected to a building element. The anchor includes a connecting head for connecting the building element to a handling machine, and a body portion including active parts that, when the anchor is connected to the construction element, ensure the adhesion of the anchor to the material of the building element. The body includes at least one land including at least one face.
Patent HK-1151778-A1 (HK)
Title: Elevator with vibration damping device
Inventor: NOGUCHI NAOAKI
IPC: B66B/
Filed: 2011-06-13
Abstract: The present invention provides an elevator with a damping device, wherein the damping device not only has a strong damping capacity, but also can implement miniaturization, in particular reduce dimension in a height direction, and be controlled stably. In the elevator with the damping device, an elevator car (1) can move up and down along a guide way arranged in a lifting passage to detect vibration of the elevator car (1), an actuator (27) is controlled to drive based on a detected signal, wherein the elevator comprises a pair of circular disks (21a, 21b) supported by a rotating shaft (41) and hammers (22a, 22b) arranged at a position depart from the rotating shaft (41) on each circular disk, and the circular disks (21a, 21b) are drive to rotate by the actuator (27).
Patent HK-1160392-A1 (HK)
Title: Determination of the prognosis of a patient undergoing treatment for alzheimer's disease
Inventor: SCHENK DALE B
IPC: A61P25/28
Filed: 2012-01-30
Abstract: Disclosed are pharmaceutical compositions and methods for preventing or treating a number of amyloid diseases, including Alzheimer's disease, prion diseases, familial amyloid neuropathies and the like. The pharmaceutical compositions include immunologically reactive amounts of amyloid fibril components, particularly fibril-forming peptides or proteins. Also disclosed are therapeutic compositions and methods which use immune reagents that react with such fibril components.
Patent HK-1003562-A1 (HK)
Title: Contrast medium composition
Inventor: GUNDERSEN HELGE GUTTORM
IPC: A61K49/18
Filed: 1998-03-27
Abstract: There is provided a contrast medium composition comprising magnetically responsive particles and a physiologically tolerable, incompletely hydrated viscosity enhancing agent.
Patent HK-1009700-A1 (HK)
Title: Triazolopyridazines as antioasthmatics
Inventor: MIYAKE AKIO
IPC: C07D/
Filed: 1998-09-08
Abstract: Novel compound represented by the formula: <CHEM> wherein R<1> stands for H, an optionally substituted lower alkyl group or a halogen; R<2> and R<3> respectively stands for a hydrogen or an optionally substituted lower alkyl group, or R<2> and R<3> may, taken together with the adjacent -C=C- group, form a 5- to 7-membered ring; X stands for O, SO or SO2; Y stands for a group of the formula:   <CHEM> (R<4> and R<5> respectively stand for H or an optionally substituted lower alkyl group) or a divalent group derived from an optionally substituted 3- to 7-membered homocyclic or heterocyclic ring; R<6> and R<7> each stands for H, an optionally substituted lower alkyl group, an optionally substituted cycloalkyl group or an optionally substituted aryl group, or R<6> and R<7> may, taken together with the adjacent N, form an optionally substituted N-containing heterocyclic group; m stands for 0 to 4; n stands for 0 to 4, or a salt thereof, which has excellent anti-PAF activities anti-LTC4 activities and anti-ET-1 activities, and is of value as an antiasthmatic agent, and their production, intermediates and pharmasceutical compositions.
Patent HK-1011618-A1 (HK)
Title: Cdw52-specific antibody for treatment of multiple sclerosis
Inventor: HALE GEOFFREY
IPC: A61K31/57
Filed: 1998-12-07
Abstract: The invention relates to the use of an antibody recognising the CDw52 antigen in the treatment of multiple sclerosis. Preferably the antibody is the humanised antibody in the humanised antibody CAMPATH-1H.
Patent HK-1021801-A1 (HK)
Title: Composition for gene transfer to the central nervous system
Inventor: CHERSKEY BRUCE
IPC: A61K35/76
Filed: 1999-12-30
Abstract: The present invention relates to a method for implanting producer cells into the mammalian brain. The producer cells are engineered with a retroviral based recombinant vector encoding a tumorcidal factor or susceptibility factor that confers on tumor cells sensitivity to chemotherapeutic or radiotherapeutic agents. Prior to transplantation into the mammalian brain, the producer cells are first cultured in vitro on a support matrix to increase the long-term viability of the transplanted cells and to provide long-term functional benefit.
Patent IE-20030664-A1 (IE)
Title: A tamper evident cap
Inventor: MCCOURT SEAN
IPC: B65D41/48
Filed: 2003-09-12
Abstract: The present invention is concerned with a tamper evident cap for use with a valve having a circumferential groove therein, for example a conventional valve used with LPG containers.  The cap comprises a body having a circumferential sidewall which, in use, surrounds the circumferential groove of the valve, the sidewall having a pair of barbs which are seated within the circumferential groove in us, in order to prevent removal of the cap from the valve once pressed into position thereon.  In order to facilitate removal of the cap from the valve, the sidewall incorporates a strip which may be  torn away from the sidewall in order to permit the sidewall to be deformed outwardly away form the circumferential groove.
Patent IE-20070778-A1 (IE)
Title: Work piece holding system
Inventor: MCNEELA FELIM PATRICK
IPC: B23Q3/18
Filed: 2007-10-25
Abstract: The invention relates a work piece holding system comprising: a block and a work piece for use in the manufacture of injection moulds, the system having a locating means for locating the block and work piece relative to one another as required. The locating means is slideably engageable between the work piece and the block and is provided at the centre of the block and work piece, and is configured to enable the rotation of the work piece relative to the block to enable an accurate alignment of the two.  The locating means comprising a dowel provided in one of the work piece or block and a corresponding dowel hole provided in the other of the corresponding block or work piece.  The block comprises a steel insert and the dowel hole, for receiving said corresponding dowel in the block, is provided in said steel insert. <Figure 4>
Patent IE-20220105-A1 (IE)
Title: A gas infusion capsule
Inventor: DAVIES STEVEN
IPC: B67D1/00
Filed: 2020-11-10
Abstract: A gas infusion capsule (20) has two liquid beverage product lines (14A, 14B) running through it and a coolant send (19)/return (21). There is also at least one gas inlet (23) and at least two gas infusers, each in line with and corresponding to a liquid beverage product line respectively and each configured for operating on a supply of gas received from the gas inlet.
Patent IT-BO950316-A1 (IT)
Title: Giunto per avvolgifiocchi
Inventor: MAGALOTTI GIANFRANCO
IPC: F16L/
Filed: 1995-06-22
Abstract: Giunto per gli estremi contigui di due segmenti successivi di un profilato tubolare di un avvolgifiocco in cui un'anima è destinata ad essere innestata entro lo stesso profilato in corrispondenza di tali due estremi e in cui i due estremi e l'anima suddetti sono destinati ad essere reciprocamente ed amovibilmente fissati da rispettivi organi molleggiati.
Patent IT-CT910013-A1 (IT)
Title: Bio-innesco "nutrior bio-dinamo"
Inventor: DR SSA MACCAGNANO MARIA GRAZIA
Filed: 1991-06-24
Abstract: Invenzione industriale su basi fisico-biologiche, da impiegare nell'alimentazione zootecnica ed umana, che permette una naturale "spinta di sviluppo" massimale agli "embrioni dei vari semi", con la risultante di uno sfruttamento integrale nutrizionale del seme stesso, mediante l'impiego dei seguenti fattori:1°) Una Biostimolazione con speciale tipo di laser;2°) L'impiego di estratti di cellule sessuali endopollinici ed ovarici vegetali;3°) La produzione di speciali fitostimoline naturali.Questi fattori formano il "Bio-Innesco NUTRIOR BIO-DINAMO", mediante il quale si produrranno super-mangimi e super-alimenti umani, che consentiranno una maggiore resa carnea detossicata in zootecnia ed una maggiore resa nutrizionale umana.
Patent IT-MC930071-A1 (IT)
Title: Centrifugazione crescente di pendolo con differenza raggi e sfere
Inventor: SERI RANIERO
Filed: 1993-09-02
Abstract: Energia illimitata per alternatori, macchine e pompe.(Un foro nel muro inespugnabile del MOTO perpetuo può aprire un fiume di PACE, benessere, ecologia per tutti anche nei deserti. Forse si riesce con una ruota, sulla cui circonferenza nicchie contengono sfere libere di salire al soffitto del coperchio con l'accelerazione iniziale, e poi accrescerla sfruttando la differenza tra la parte bassa del coperchio tenuta al centro girevole da corda, e la parte alta che afferra un palo piantato sulla stessa circ.za, che può essere anche molto lungo (differenza raggi). Quindi la spinta radiale delle sfere metà (anche meno) si scarica al centro, e metà (anche più) serve alla spinta crescente della ruota pendolo. Dall'esterno proviene la cinghia del moltiplicatore di velocità, mosso da altro pendolo circolare. L'inventore SERI Raniero via s. Lucia 17 - Serravalle di Macerata - 62038 - Italy propone la fabbricazione di elettrogeni e turbine e RIVENDICA: 1) pesi in coppia su ruota appoggiati in modo che parte della spinta radiale si scarichi al centro e parte su aste in circonferenza. N.B. Urge più ONU, più disciplina e più Spiritualità cristiana e musulmana, e il salario alle casalinghe).
Patent IT-MI921666-A1 (IT)
Title: Bigodino per l'ondulazione differenziata dei capelli
Inventor: GORI OLIVO
IPC: A45D/
Filed: 1992-07-08
Abstract: Bigodino costituito da un corpo sagomato comprendente due superfici anulari concave (1,2) che si intersecano perpendicolarmente in corrispondenza di due punti (3, 3') appartenenti ad un asse (A3) di simmetria del corpo stesso, detto corpo essendo inoltre provvisto di canali interni comunicanti (5, 5', 6, 6', 7) accessibili dall'esterno.
Patent IT-MI942510-A1 (IT)
Inventor: PASUT CLAUDIO
IPC: F16K31/08
Filed: 1994-12-14
Abstract: A solenoid valve for an irrigation control unit comprises a cut-off element (7) movable inside a respective seat (25, 26) between a closed position and an open position; the cut-off element (7) defines inside the seat (25, 26) a chamber (26) in constant communication with the inlet (2) of the solenoid valve, so that the pressure exerted on the cut-off element (7) by the water present at the inlet of the solenoid valve is balanced by the pressure exerted on the cut-off element (7) by the water present in the chamber (26), the cut-off element (7) is provided with a passing conduit (12) that can be opened so that the chamber (26) can be put in communication with the outlet (3) of the solenoid valve so that, since the pressure exerted on the cut-off element (7) by the water present at the inlet of the solenoid valve is no longer balanced by the pressure exerted on the cut-off element (7) by the water present in the chamber (26), the cut-off element (7) is displaced by the thrust of the water present at the inlet of the solenoid valve in said open position; the solenoid valve also comprises a bistable electromagnetic device (14-22) comprising an electromagnetically-operated valve suitable for determining alternatively the closing and the opening of said passing conduit (12) as a result of the generation of an electrical control impulse and up to the generation of an opposite electrical impulse. <IMAGE>
Patent IT-MI981833-A1 (IT)
Inventor: GIORGI RAFFAELLO
IPC: C07D207/16
Filed: 1998-08-04
Abstract: A process for the preparation of polymorph A of zofenopril calcium salt in substantially pure form, which comprises: 1) reaction of S(-)-3-benzoylthio-2-methylpropanoic acid chloride with cis-4-phenylthio-L-proline in water at pH ranging from 9.0 to 9.5 and recovery of zofenopril in the acidic form; b) salification of acid zofenopril with a poyassium salt in alcoholic solution, and recovery of the resulting potassium salt; c) conversion of the potassium salt to the calcium salt by addition of zofenopril potassium salt aqueous solution to a CaCl2 aqueous solution at a temperature of 70-90° C. with simultaneous seeding to promote the precipitation of polymorph A.
Patent IT-PD960261-A1 (IT)
IPC: B60B1/04
Filed: 1996-10-24
Abstract: A spoke nipple comprises a body (2) of substantially undeformable material with a head (5) and a shank (4) which have an at least partially threaded axial hole (3) for housing the thread (18) of a spoke (19), and with a perforated insert (16; 22) of substantially deformable material fixed to the body (2) with the holes (3; 17) in the body and in the insert (16; 22) arranged coaxially, the insert having an inside diameter such as to house the thread (18) of the spoke (19) with interference when it is screwed into the axial hole (3) in the nipple body (2). <IMAGE>
Patent IT-RM910788-A1 (IT)
Inventor: ALLEN GEOFFREY
IPC: C07K1/20
Filed: 1991-10-16
Abstract: Following are described. (A) purified prepn. of an anti-CDw52 antibody which exhibits on size exclusion chromatography a single peak under non-reducing conditions and 2 major peaks under reducing conditions; esp. the prepn. exhibits on conventional SDS polyacrylamide gel electrophoresis, one main band using a non-reduced sample and two main bands using a reduced sample; (B) purified prepn. of an anti-CDw52 antibody having a specific activity greater than 0.8 KU/mg; (C) purified prepn. of an anti-CDw52 antibody, free from host cell contaminants and/or aggregates; (D) purifying an anti-CDw52 antibody comprising (a) applying an aqs. soln. of the antibody to a Protein A column so as to absorb the antibody and eluting the antibody with an acid soln., (b) applying the acidic eluate to an ion-exchange column of charged particles to absorb the antibody and then eluting the antibody with an aqs. soln. of counter-charged ions and (c) applying the aqs. eluate to a size exclusion column of porous particles to retain non-antibody mols. in the porous particles and to obtain the desired antibody in selected fractions produced from the column. Pref. the Protein A column is Protein A Sepharose and the antibody is eluted with citric acid.
Patent IT-RM940778-A1 (IT)
Title: "procedimento per il tiraggio di un monocristallo di silicio"
Inventor: VON AMMON WILFRIED
IPC: C30B15/22
Filed: 1994-11-28
Abstract: L'invenzione riguarda un procedimento per il tiraggio di un monocristallo di silicio, nel qual caso il monocristallo viene tirato con una velocità definita come velocità di tiraggio limite in direzione verticale a una massa fusa di silicio contenuta in un crogiolo. Il valore della velocità di tiraggio limite è approssimativamente proporzionale al gradiente di temperatura assiale nel monocristallo che cresce.
Patent IT-TV950075-A1 (IT)
Title: Boiler perfezionato, particolarmente nelle apparecchiature per la cot-  tura a vapore di alimenti
Inventor: LAZZER NATALINO
IPC: F22B/
Filed: 1995-06-19
Abstract: Boiler perfezionato, particolarmente nelle apparecchiature per la cottura di alimenti, del tipo a vapore, comprendenti un boiler per la produzione di vapore istantaneo in cui si prevede:- delle tasche protese, sfalsate l'una dall'altra, lungo il contenitore e da un lato impegnate allo stesso, dall'altro essendo sostenute da un fermo posteriore;- delle resistenze, diversamente sviluppate introdotte all'interno delle dette tasche, il cui percorso compie rispettivamente l'andata ed il ritorno;- una struttura di contenimento dell'assieme tasche-resistenze e massa termica, interna al detto contenitore, composta da un fondo sagomato e da almeno due pareti perpendicolari, ottenendo perimetralmente una intercapedine;- una lamiera forata a chiusura della precedente struttura di contenimento e posta al di sopra della massa termica per essere così trattenuta;- una massa termica costituita da elementi particolarmente conformati;- infine, un tubo di immissione dell'acqua all'interno del contenitore il quale di testa è provvisto di un diffusore per la distribuzione a ventaglio.
Patent IT-UD960213-A1 (IT)
Inventor: POLESE GIOVANNI
IPC: B65G47/256
Filed: 1996-11-05
Abstract: Automatic loader of ferrules (11) for brushes (12) to be fed one at a time to a ferrule-assembling machine, the ferrules (11) being structured in the form of a closed ring of sheet metal, the edges being super-imposed and crushed along one of the narrow sides so as to constitute an outer closing projection (15), the outer closing projection (15) defining a rounded side (16) and a protruding fold (17), the ferrules (11) able to include circumferential ribs (18a, 18b) and/or identification markings, the loader including a feeder-vibrator assembly (19) equipped with a frame (20) comprising, in cooperation with the side wall (21), a guide channel (23) with a transport plane on which the ferrules (11) advance, the bottom wall (24) of the guide channel (23) being connected to the side wall (21) of the frame (20), the guide channel (23) connecting the frame (20) to the loading area of the ferrule-assembling machine, the loader comprising means (29) to monitor the directioning of the ferrules (11) and expulsion means (30) cooperating with the guide channel (23) in a position upstream from the loading area of the ferrule-assembling machine, the expulsion means (30) being governed by monitoring means (29) so as to return an incorrectly directioned ferrule (11) to the frame (20) of the vibrator-feeder assembly (19). <IMAGE>
Patent IT-VI930041-A1 (IT)
Inventor: CORNER ANTONIO
IPC: C14B1/58
Filed: 1993-03-18
Abstract: A vacuum apparatus for industrial hide driers with multiple beds (2) includes a circuit with an open end (17) having arranged in a series: a vapor manifold (7) for each bed; a first condenser (8) inserted in each manifold; a first condensate separator (10) at the output of the various condensers (8); a main vacuum pump (16) to gradually reduce the absolute pressure in the circuit to a first upper value (Ps). A particular feature of the system consists of the fact that it has a secondary aspiration device (19) which is arranged upstream of the main vacuum pump (16) to operate in series to this pump when the first value of the absolute pressure (Ps) is reached, so as to further reduce the pressure of the circuit to a second lower value (Pi). The upper value (Ps) of the absolute pressure is 40 to 100 mbar; the second lower value (P1) of the absolute pressure is 15 to 1 mbar. The device (19) is a high-capacity, low-head blower.
Patent IT-VR980012-A1 (IT)
Inventor: ZANDONA RENZO
IPC: E04F11/032
Filed: 1998-02-24
Abstract: Monolithic helical step (10) made of reinforced concrete, suitable for obtaining helical staircases, in the proximity of the internal side surface (11) of which a through hole (12), which is located parallel to the tread plane (18), is suitably positioned to receive a concrete or resin casting inside it and a falsework member (13) by means of which the connection of a plurality of superimposed steps (10) is assured. <IMAGE>
Patent NO-20111679-A1 (NO)
Title: System og fremgangsmate for handtering av en gruppe ventiler
Inventor: ANTONSEN ROGER
IPC: E21B34/14
Filed: 2011-12-09
Abstract: Et ventilsystem som sørger for væskestrømning gjennom radiale åpninger anordnet langs en aksial lengde av et rør. Røret omfatter minst en ventilgruppe som inneholder minst to ventiler som betjenes av en fallkule. En innsats 302, f.eks. av standard stål, anordnet i en hardere liner eller foring 301 i åpningen, sørger for en liten mellomåpning for i det minste den tiden det tar å åpne alle de gjenværende ventiler i gruppen. Den lille åpningen begrenser trykkfallet over ventilen. Når alle ventiler er åpne, er innsatsen 302 erodert bort av et slipende materiale, f.eks. et slam eller slurry brukt for hydraulisk frakturering eller oppsprekking, og permanente fullåpninger blir opprettet eller dannet.
Patent PE-54797-A1 (PE)
Title: Tetralinas
Inventor: SWOBODA ROBERT
IPC: C07C211/42
Filed: 1996-05-03
Abstract: SE REFIERE A COMPUESTOS DE FORMULA GENERAL (I), DONDE: R1 Y R2 SON INDEPENDIENTEMENTE H, ALQUILO C1-C4 o ALCOXI C1-C4, ENTRE OTROS; R3 ES H, OH o ALCOXI C1-C4, ENTRE OTROS; R4 Y R5 SON INDEPENDIENTEMENTE H o ALQUILO C1-C4, ENTRE OTROS o FORMAN JUNTO CON EL ATOMO DE NITROGENO UN PIRROLILDINILO o PIPERIDINO, ENTRE OTROS; SIENDO PREFERIBLEMENTE DICHO COMPUESTO (R)-1, 2, 3, 4- TETRAHIDRO-8-METOXI-N,N-DIMETIL-5-[4-TRIFLUOROMETIL]FENIL-2-NAFTALENAMINA. TAMBIEN SE REFIERE A UN PROCESO PARA LA PRODUCCION DE LOS COMPUESTOS (I) QUE COMPRENDE HACER REACCIONAR UN 1, 2, 3, 4-TETRAHIDRO-2-NAFTALENAMINA QUE PRESENTA UN HALOGENO SOBRE EL ANILLO AROMATICO CON UN ACIDO FENILBORONICO OPCIONALMENTE SUSTITUIDO Y EL COMPUESTO RESULTANTE SE RECUPERA EN FORMA DE BASE LIBRE O DE SAL DE ADICION DE ACIDO. SE USA EN EL TRATAMIENTO DE EPILEPSIA, ATAQUE APOPLEJICO Y TRAUMA CEREBRAL O ESPINAL
Patent PE-12998-A1 (PE)
Title: Amortiguador modular
Inventor: WEGLEWSKI JAMES T
IPC: F16F15/08
Filed: 1996-07-18
Abstract: CARACTERIZADO POR TENER CADA MIEMBRO AMORTIGUADOR, PILAS DE ELEMENTOS AMORTIGUADORES Y COMBINACIONES DE LOS MISMOS, EL CUAL COMPRENDE: A) DOS MIEMBROS RIGIDOS EXTERNOS, SELECCIONADOS DEL GRUPO QUE CONSISTE DE BARRAS, VARILLAS, PLACAS, VIGAS I, VIGAS T, VIGAS U, ANGULOS Y SECCIONES TUBULARES; B) UNA CAPA DE MATERIAL AMORTIGUADOR DE VIBRACIONES ENTRE LOS DOS MIEMBROS RIGIDOS EXTERNOS; C) OPCIONALMENTE UNO O MAS MIEMBROS RIGIDOS INTERNOS, COLOCADOS EN EL INTERIOR DE LOS MIEMBROS RIGIDOS EXTERNOS, EN DONDE CADA MIEMBRO RIGIDO DEL ELEMENTO AMORTIGUADOR ESTA SEPARADO DE OTRO MIEMBRO RIGIDO POR UNA CAPA DE MATERIAL AMORTIGUADOR DE VIBRACIONES; Y D) OPCIONALMENTE UNA CAPA DE ADHESIVO ENTRE LOS MIEMBROS RIGIDOS Y LAS CAPAS DE MATERIAL AMORTIGUADOR DE VIBRACIONES. TALES AMORTIGUADORES SON USADOS EN LA AMORTIGUACION DE ESTRUCTURAS COMO EDIFICIOS, PUENTES, ETC
Patent PE-108698-A1 (PE)
Title: Derivados 6,6-heterobiciclicos sustituidos
Inventor: YUHPYNG LIANG CHEN
IPC: A01N43/653
Filed: 1997-08-22
Abstract: SE REFIEREN A COMPUESTOS DE FORMULA (I), EN DONDE: "A" ES N o CR7; "B" DE PREFERENCIA ES CHR1R2, NHCHR1R2 o OCHR1R2, Y EL GRUPO CHR1R2 ES CICLOPENTANO, TETRAHIDROFURANO o TETRAHIDROTIENILO; "G" ES N, CR4 o C; "K" ES (i) N o CR6 CUANDO ESTA UNIDO POR UN DOBLE ENLACE A "G" o "E", (ii) O, S, CO, CS, CR6R12 o NR8 o (iii) UN GRUPO SEPARADOR DE 2 ATOMOS, EN DONDE UNO DE LOS 2 ATOMOS ES O, N, S, CO, CS, CR6R12, NR6 o CR6 Y EL OTRO ES CR6R12 o CR9; "D" Y "E" SON CO, CS, S, O, CR4R6, NR8, N o CR4; EL ANILLO DE 6 o 7 MIEMBROS QUE CONTIENE "D", "E", "K" Y "G" TIENE DE 0 A 2 HETEROATOMOS Y DE 0 A 2 GRUPOS CO o CS; R1 ES ALQUILO C1-C6; R2 ES ALQUILO C1-C12 OPCIONALMENTE CON 1 A 3 DOBLES O TRIPLES ENLACES, ARILO o (ALQUILENO C1-C4)ARILO; R3 ES H, ALQUILO C1-C4, DE PREFERENCIA ES METILO; R5 ES FENILO, NAFTILO, PIRIDILO o PIRIMIDILO, DE PREFERENCIA ES 2,4,6-TRIMETIL-FENIL o 4-HALOGENO-2,6-DIMETILFENIL; R4, R6, R8, R9 Y R12 SON DE PREFERENCIA H; R7 ES H, METILO, ENTRE OTROS. TAMBIEN SE REFIEREN A LOS COMPUESTOS INTERMEDIOS EN LA PREPARACION DE (I), DONDE "A", "D", "E", "K" Y "G" SON C; "B" ES OH, Cl, Br, I o OTf. LOS COMPUESTOS DE FORMULA (I) ACTUAN COMO INHIBIDORES DE LA PROTEINA DE UNION A LA HORMONA DE LIBERACION DE CORTICOTROPINA (CRH), SIENDO UTILES EN EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER Y LA OBESIDAD, ENTRE OTROS
Patent PE-14991-A1 (PE)
Inventor: SINCLAIR KIRK MCBRIDE
IPC: E21B6/00
Filed: 1990-12-21
Abstract: A dry, vertical shaft drilling system including an inverted raiseboring cutterhead (12) fitted with air nozzles (42) and vacuum pickups. Weights (16) are detachably stacked above the cutterhead. Cuttings are extracted through the weights into a swivel (26) circumscribing the drill string (20). The swivel is a transition from the rotating cutterhead to the stationary extraction riser pipes (18) disposed above the swivel. Non-rotating stabilizers stabilize the drill string. <IMAGE>