baber/WOPTO huggingface dataset:
Patent JP-2017534428-A (JP)
Title: 最小侵襲性作業通路の近位端の固定
IPC: A61B17/56
Filed: 2015-11-17
Abstract: 本発明は、作業通路の近位端部が横方向にゼロの移動範囲又は限られた移動範囲のいずれかを有する最小侵襲性システムを目的とする。第１の実施形態は、一対のフランジに取り付けられた摺動可能なカラーを有し、カラーの動きは環状フレームによって境界が定められる。第２の実施形態は、管に取り付けられた実質的に球状の要素を有する。第３の実施形態は、複数のキャップを有する。第４の実施形態は、より大きな作業通路のために適合される。
Patent JP-2018508512-A (JP)
Title: がんを治療するためのｐｄ−１／ｐｄ−ｌ１阻害剤
IPC: A61P35/00
Filed: 2016-02-23
Abstract: 本発明は、ＰＤ−１受容体とそのリガンドＰＤ−Ｌ１との相互作用の阻害剤の治療上有効量を対象に投与することを含む、対象におけるがんを治療する方法に関する。
Patent JP-2018509911-A (JP)
Title: Ｍｈｃ細胞ライブラリーを用いる、新規の免疫原性ｔ細胞エピトープの検出方法および新規の抗原特異的ｔ細胞受容体の単離方法
IPC: A61K48/00
Filed: 2016-03-15
Abstract: 本発明は、免疫療法の分野に関し、特に、養子Ｔ細胞療法、Ｔ細胞受容体(ＴＣＲ)遺伝子療法およびワクチン接種に関する。本発明は、ドナーから単離されたＴ細胞を、該ドナー中に、好ましくはＫ５６２細胞中に存在する全てのＭＨＣ ＩまたはＭＨＣ ＩＩアレルを発現する細胞を含む人工抗原提示細胞(ＡＰＣ)のライブラリーと接触させることを含む、主要組織適合複合体(ＭＨＣ)上に提示される抗原由来のエピトープに特異的なＴＣＲ構築物のＴＣＲα鎖構築物(ＴＲＡ)およびＴＣＲβ鎖構築物(ＴＲＢ)をコードする核酸を調製する方法を提供する。ＴＣＲ構築物はＴ細胞で発現され得て、それは、例えば、癌、ウイルス感染または自己免疫疾患などの養子Ｔ細胞療法に有用である。本発明はさらに、該ＴＣＲにより認識されるエピトープを同定するための方法を提供する。該ＴＣＲにより認識される免疫原性エピトープは、患者において抗原特異的Ｔ細胞免疫を誘導するためのワクチン製剤を開発するために使用され得る。本発明はさらに、本発明の方法により得られる２つのＴＣＲ構築物のペアおよびそれぞれの免疫原性エピトープを提供し、ここで、該エピトープは、ヒトパピローマウイルス(ＨＰＶ)１６(アルファパピローマウイルス９とも称する)オンコプロテインＥ５およびヒトサイトメガロウイルス(ＣＭＶ)タンパク質ｐｐ６５由来である。
Patent JP-2018509986-A (JP)
Title: リンク品質評価を伴う医療装置システムにおける通信
IPC: A61N1/36
Filed: 2016-03-15
Abstract: 植込み型医療装置システムをテストおよび構成する方法および装置が開示されている。第一医療装置および第二医療装置は、通信信号の品質に関連するデータを提供するように構成されたテスト信号を用いて互いに通信し、通信手段の最適化を促進する。適切な通信の可用性を保証するように医療装置の一つを移植するため、手術中にいくつかの方法を実行することができる。
Patent JP-2018513303-A (JP)
Title: 液化ガス用のインジェクタ弁をテストする方法
IPC: F02M61/16
Filed: 2016-03-29
Abstract: メタノールなどのような液化ガス用のインジェクタ弁をテストする方法。２ストローク燃焼エンジンのためのメタノール用の新しいインジェクタ弁がMAN Diesel & Turboによって開発されている。インジェクタ弁には、シーリング油と、液化ガスの供給を制御するための制御油とが供給される。漏れは、もしあれば、非常に危険なものとなり得る。本発明によれば、インジェクタ弁は、ホルダ（２）内に配置され、上部カバーが除去され、接続部片（８）と置き換えられ、開弁圧に達し、インジェクタ弁がスプレーチャンバ（２９）内でスプレーするまで、制御油の圧力が増大される。その結果、開弁圧をチェックすることができる。
Patent JP-2018509880-A (JP)
Title: 自動車の中の電池のエネルギー状態の値を決定するための方法及び装置
IPC: B60L50/16
Filed: 2015-01-13
Abstract: 本発明は、自動車（１；１）の中の再充電可能な電池（５）のエネルギー状態（ＳＯＥ）の値を決定するための方法であって、前記電池（５）が、電気消費体（４）に接続されており、前記方法が、前記電池（５）の現在の容量の尺度として、充電状態（ＳＯＣ）を決定すること；及び前記エネルギー状態（ＳＯＥ）を、少なくとも前記電池（５）の残存充電及び放電エネルギーの指標として決定することを含む場合において、前記方法が、前記エネルギー状態（ＳＯＥ）の値を、前記電気消費体（４）の作動に関連する少なくとも一つのパラメータ（Ｉ，Ｒ，ＳＯＣｍａｘ，ＳＯＣｍｉｎ）に基づいて計算して決定することを含み、前記少なくとも一つのパラメータ（Ｉ，Ｒ，ＳＯＣｍａｘ，ＳＯＣｍｉｎ）が、前記電池（５）の充電又は放電中に前記自動車（１；１）又は電気消費体（４）の作動のためのモードに依存して変化することを特徴とする方法に関する。また、本発明は、自動車（１；１）の中の再充電可能な電池（５）のエネルギー状態（ＳＯＥ）の値を決定するための装置にも関する。【選択図】 図２ｂ
Patent JP-2018516879-A (JP)
Title: Ｈｐｖ１６−ｅ７ペプチド／ｍｈｃ複合体を標的化する構築物およびその使用
IPC: C12N1/19
Filed: 2016-05-06
Abstract: 本出願は、ＨＰＶ１６−Ｅ７ペプチドおよびＭＨＣクラスＩタンパク質を含む複合体に特異的に結合する抗体部分を含む構築物を提供する。これらの構築物を作製および使用する方法もまた提供される。本発明は、例えばヒトパピローマウイルスサブタイプ１６（ＨＰＶ１６）Ｅ７ペプチドおよび主要組織適合複合体（ＭＨＣ）クラスＩタンパク質を含む複合体（ＨＰＶ１６−Ｅ７／ＭＨＣクラスＩ複合体、またはＥ７ＭＣ）に特異的に結合する抗体部分を含む、単離された抗Ｅ７ＭＣ構築物を提供する。【選択図】図８Ａ
Patent JP-2018522265-A (JP)
Title: ディスプレイパネルを照明するためのガラス物品
IPC: G02F1/13357
Filed: 2016-05-12
Abstract: 例えば導光板など、ディスプレイパネルを照明するためのガラス物品、特に、複数の個別のセグメントによって形成されたガラス基板を含む導光板が本明細書に開示され、該複数のガラスセグメントは、二次元配列においてエッジ・トゥ・エッジで配列され、かつ、少なくとも２つのポリマーフィルム間に積層される。該ガラス物品を取り入れたディスプレイ装置についても記載される。
Patent JP-2018517521-A (JP)
Title: 洗濯分類機能を有する洗濯機
IPC: D06F29/00
Filed: 2015-11-30
Abstract: 本発明は、洗濯分類機能を有する洗濯機を開示する。洗濯分類機能を有する洗濯機は、ハウジング（１）と、ハウジング内に設置された第１の自動洗濯システム（２）及び第２の自動洗濯システム（３）と、を備える。ハウジング（１）は、第１の自動洗濯システム（２）を収容する第１の洗濯領域（４）と、第２の自動洗濯システム（３）を収容する第２の洗濯領域（５）とを有し、前記第１の洗濯領域（４）と前記第２の洗濯領域（５）とは左右方向に設置される。前記第１の自動洗濯システム（２）の軸線と前記第２の自動洗濯システム（３）の軸線とが垂直される。ユーザは、ニーズに従って１つの自動洗濯システムを起動するか、または二つの自動洗濯システムを同時に起動するかを選択することができる。よって、洗い行程において洗い水を収容する収容筒の搖動方向と振幅が異なることによって、二つの収容筒との間の間隔距離が小さく設置される。ハウジング（１）の受力方向と位置が異なることによって、二つの自動洗濯システムが同時に洗い時に振幅や作用力を直接に重畳することを防ぎ、ハウジング（１）が受ける作用力が分散されることによって、ハウジング（１）の変形を防いだ。 【選択図】図２
Patent JP-2018525975-A (JP)
Title: たばこ製品を作成する方法
IPC: A24B3/14
Filed: 2016-07-20
Abstract: 三次元たばこ物体を作成する方法は、約１００マイクロメートル〜約４００マイクロメートルの平均粒径を有するたばこ粒子を含むたばこダストを提供することと、たばこダストを含有する水性スラリーを調製することと、スラリーを付加製造システムのプリントヘッドへと供給することと、たばこ物体の連続層を形成するためにプリントヘッドによってスラリーを分与することと、を含む。【選択図】図１
Patent JP-2018523396-A (JP)
Title: デジタル画像変換方法、装置、記憶媒体及び機器
IPC: H04N9/04
Filed: 2015-12-25
Abstract: 本開示の実施形態はデジタル画像変換方法及び装置を開示する。前記方法は、前方相関ピクセルのＲＧＢ指示信号を取得するステップと、現在のピクセルのＲＧＢ信号と前記前方相関ピクセルのＲＧＢ指示信号とを比較するステップと、現在のピクセルのＲＧＢ信号と前記前方相関ピクセルのＲＧＢ指示信号とが同じである場合、前方相関ピクセルのＹＵＶ指示信号を取得して現在のピクセルのＹＵＶ信号に割り当てるステップと、現在のピクセルのＲＧＢ信号と前記前方相関ピクセルのＲＧＢ指示信号とが異なる場合、前記現在のピクセルのＲＧＢ信号に基づいて現在のピクセルのＹＵＶ信号を再計算するステップと、を含む。本発明の実施形態に開示されたデジタル画像変換方法及び装置は画像データ変換の計算量を効果的に低下させることができる。【選択図】図１
Patent JP-2019120572-A (JP)
Title: Automatic analyzer and re-inspection instruction system
Inventor: TOMII SHINICHI
IPC: G01N35/02
Filed: 2018-01-04
Abstract: To provide an automatic analyzer and a re-inspection instruction system that can reduce time and labor to search for a sample whose re-inspection is instructed.SOLUTION: A control unit 41 included in a biochemical analyzer outputs an analysis result of analyzing a measurement value of a reactant measured by a multi-wavelength light meter 16 to a host device 50 through a communication unit 43. Then, the control unit 41 causes a display unit 44 to display sample identification information for identifying a sample whose re-inspection is instructed from the host device 50 through the communication unit 43 and sample container positional information indicating the position at a sample turn table of a sample container containing the sample whose re-inspection is instructed from the host device 50.SELECTED DRAWING: Figure 4
Patent JP-2019118895-A (JP)
Title: Ultrasonic cleaning apparatus
Inventor: ARAI TAKEO
IPC: B08B3/12
Filed: 2018-01-10
Abstract: To provide an ultrasonic cleaning apparatus capable of measuring output of ultrasonic wave in ultrasonic cleaning with a high degree of accuracy thereby enabling cleaning efficiency to be improved.SOLUTION: The ultrasonic cleaning apparatus comprises: a cleaning tank 2 in which cleaning liquid W and a cleaning object are charged; an ultrasonic vibrator 3 for radiating an ultrasonic wave in the cleaning liquid W in the cleaning tank 2; an ultrasonic wave oscillator 4 connected to the ultrasonic vibrator 3 and supplying electric power of the ultrasonic wave; an output adjustment circuit 5 controlling the electric power output from the ultrasonic wave oscillator 4; and an ultrasonic measurement unit 10 measuring output of the ultrasonic wave, the ultrasonic measurement unit 10 comprises a freely rotatable propeller 11 inserted into the cleaning liquid W, and measures the output of the ultrasonic wave by detecting rotation of the propeller 11. Thus, the output of the ultrasonic wave can be measured with a high degree of accuracy by the propeller 11 of the ultrasonic measurement unit 10. The output of the ultrasonic wave radiated from the ultrasonic vibrator 3 is suitably controlled according to the output of the measured ultrasonic wave, so that efficiency of ultrasonic cleaning is enhanced.SELECTED DRAWING: Figure 1
Patent JP-2019016341-A (JP)
Title: Test system and testing method for on-vehicle application
Inventor: TOSHIMA KAZUNARI
IPC: G01C21/26
Filed: 2018-01-10
Abstract: To provide a test system and a testing method capable of effectively performing an operation test on an on-vehicle application without requiring a test vehicle to actually run on a road.SOLUTION: A safety driving support application AP1 determines whether a test vehicle 10 comprising an on-vehicle machine 11 and a virtual vehicle 50 including a pseudo on-vehicle machine 22 intersect with each other on the basis of road structure information, driving operation information, and test data. When the determination gives an affirmative result, the safety driving support application AP1 determines a support action of a safety driving support for the test vehicle 10. A testing device 20 comprises: a test data generation unit 31 that generates test data that relatively changes simulated position information that simulates a position of the pseudo on-vehicle machine 22 and a pseudo path-side machine 21 with respect to simulated position information of the on-vehicle machine 11; and an adequacy determination unit 33 that determines whether the support action is consistent with the content of the road structure information, the driving operation information, and the test data.SELECTED DRAWING: Figure 1
Patent JP-2019124586-A (JP)
Title: Fluid line measuring apparatus and fluid line measuring method
Inventor: TAMURA YOSHITANE
IPC: G01F1/66
Filed: 2018-01-17
Abstract: To provide a fluid line measuring and inspecting apparatus capable of performing measurement inspection with high accuracy and capable of measuring not only a fluid flow velocity but also various variable amounts in spite of the fact that the measuring means does not become an obstacle in a line in spite of the measuring means of a direct measuring type in direct contact with a fluid and to provide a fluid line measuring method capable of efficiently performing measurement even for a line having a large diameter.SOLUTION: A fluid line measuring apparatus 1 mounted in a line 2 through which fluid flows and performs a predetermined measuring operation by using measuring means for at least one of the fluid and the line 2 includes a measuring unit 10 having a cylindrical holding body 11 containing the measuring means, and a watertight fixing unit 20 for fixing a cylindrical holding body 11 in a watertight manner to the line 2, and the watertight fixing unit 20 is provided with a fixing mechanism for fixing the cylindrical holding body 11 at a position at which an end surface 11a of a tip end of the cylindrical holding body 11 is exposed with an inner surface 2a of the line 2 through a hole P provided in the line 2.SELECTED DRAWING: Figure 2
Patent JP-2019124628-A (JP)
Title: Electron spin measuring holder and electron spin measuring apparatus
Inventor: MARUMOTO KAZUHIRO
IPC: G01N24/10
Filed: 2018-01-18
Abstract: To improve the workability of insertion work into the sample tube of a sample when measuring an electron spin.SOLUTION: A electron spin measuring holder (130) comprises: a substrate part (131) extended in the longitudinal direction of the sample tube (100) of an electron spin measuring apparatus (1); a first element connection part (134) electrically connected to a first electrode part (54) of a measuring element (120); a second element connection part (135) electrically connected to a second electrode part (58) of the measuring element (120); a first wiring part (132) arranged on the substrate part (131) and extended from the first element connection part (134); a second wiring part (133) arranged on the substrate part (131) and extended from the second element connection part (135); a first external connection part (136) provided on the other end side of the first wiring part (132); and a second external connection part (137) provided on the other end side of the second wiring part (133).SELECTED DRAWING: Figure 4
Patent JP-2019128188-A (JP)
Title: Mass spectrum processing apparatus and method
Inventor: SATO TAKAYA
IPC: G01N27/62
Filed: 2018-01-23
Abstract: To generate an image that reflects the entire mass spectrum of multiple pixels.SOLUTION: An ion intensity column for each mass spectrum constituting the mass spectrum array 42 is calculated. For each ion intensity column, a plurality of indicators a to d showing a plurality of features for the entire mass spectrum is calculated. A plurality of indicator distribution images 46a to 46d are calculated based on them. Based on the mass image array generated from the mass spectrum array, the plurality of indicator distribution images 46a to 46d may be calculated.SELECTED DRAWING: Figure 3
Patent JP-2018076774-A (JP)
Title: Roofing membrane with single layer having biodegradable detachment liner of multifunction type
Inventor: DAVID FRENCH
IPC: E04D5/06
Filed: 2018-01-29
Abstract: PROBLEM TO BE SOLVED: To provide a membrane roof capable of keeping a white roofing membrane clean during installation when a new membrane roof is installed.SOLUTION: A roofing laminate comprises a roofing membrane, preferably a white roofing membrane, which is covered with a protective sheet. The protective sheet is tinted so that it has a coloration distinguishable from the roofing membrane. The roofing laminate is applied to a roof surface and the release liner protects an outer surface of the roofing membrane from scrapes and dirt during installation. When the roof is installed, the protective sheets are removed from all of roofing membrane sheets, exposing a clean surface.SELECTED DRAWING: None
Patent JP-2019129959-A (JP)
Title: Bone density measuring device
Inventor: MIYAMOTO TAKANORI
IPC: A61B6/00
Filed: 2018-01-30
Abstract: To dispose an X-ray generator for radiography above a photography platform without separating a bone density measuring device from the photography platform.SOLUTION: A movable arm 14 is held at an angle selected from a first angle (θ1), a second angle (θ2), and a third angle (θ3). When the third angle is selected, the movable arm 14 is roughly in a standing posture, and a space above a mounting table 18 is opened. An X-ray detector, etc. for radiography can be disposed in the space above the mounting table. The movable arm 14 is provided with an upper side release button and a lower side release button for releasing the state of holding the movable arm 14. The movable arm 14 includes an inclined plane 14E.SELECTED DRAWING: Figure 1
Patent JP-2019130069-A (JP)
Title: Game machine
Inventor: ASANO HIROYUKI
IPC: A63F7/02
Filed: 2018-01-31
Abstract: To provide a game machine capable of suitably executing a performance set to a game machine.SOLUTION: In variation display that displays a predetermined story image including an image for capturing "cats" during execution of variation display in satisfaction of a predetermined performance-granting condition by capturing "cats" as one of animal characters, and is executed after variation display for displaying the story image, an effective period in which a performance corresponding to satisfaction of a performance-granting condition is executable is generated. A real notification accessory 601 as decoration means capable of changing appearance from an invisible state to a visible state is provided while "cats" as one of animal characters to be collected are formed to be in a shape of "tigers" in a changed form, and a sub-control board performs control for changing the appearance of the real notification accessory 601 in acquisition of "cats" corresponding to "tigers".SELECTED DRAWING: Figure 20
Patent JP-2019134335-A (JP)
Title: Imaging apparatus, control method, and program
Inventor: YOSHIDA AKIMITSU
IPC: G03B17/18
Filed: 2018-01-31
Abstract: To reduce a sense of discomfort given to a user when a plurality of images corresponding to images acquired at different resolutions are switched and continuously displayed.SOLUTION: An imaging apparatus includes: display means for acquiring a first image and a second image having a lower resolution than the first image, and capable of displaying a first display image corresponding to a first image and a second display image corresponding to a second image; and display control mode, during continuous imaging, for switching between the first display image and the second display mode to be displayed on the display means continuously and for setting a first display mode and a second display mode different from the first display mode. In the first display mode, with respect to the second display mode, the time after the first display image is displayed and then the second display image is displayed is short. The display control means switches between the first display mode and the second display mode, on the basis of information on movement of the subject during continuous imaging.SELECTED DRAWING: Figure 1
Patent JP-2019134360-A (JP)
Title: Imaging apparatus
Inventor: TOTORI YUKI
IPC: H04N5/225
Filed: 2018-02-01
Abstract: To provide an imaging apparatus capable of suppressing a shift in relative position between an imaging apparatus main body and an imaging device due to an impact such as dropping, and capable of suppressing assembly costs.SOLUTION: The imaging apparatus includes: a screw member in which a first screw portion is formed on an outer peripheral portion and a second screw portion is formed on an inner peripheral portion; a structure fastened by the first screw portion; a fixing screw that is screwed into the second screw portion; and a holding member fixed to the structure by the screw member and the fixing screw while holding an imaging device that converts an optical image of a subject imaged by an optical system into an electrical signal. The first screw portion and the second screw portion are in a reverse screw relationship.SELECTED DRAWING: Figure 4
Patent JP-2019135030-A (JP)
Title: Ammonia removal system
Inventor: KOJIMA KEISUKE
IPC: C02F1/20
Filed: 2018-02-05
Abstract: To provide an ammonia removal system that can remove efficiently ammonia with a reduced amount of aeration.SOLUTION: An ammonia removal system has: a first ammonia removal part 4 having aeration means 3 that stores treatment water 1 and diffuses air 2 to aerate the treatment water 1; and a first ammonia recovery part 7 having first ventilation means 6 that stores recovery liquid 5 and flows the air 2 to the recovery liquid 5 from a gas phase of the first ammonia removal part 4.SELECTED DRAWING: Figure 1
Patent JP-2019135758-A (JP)
Title: Coil component
Inventor: TAKENAKA KAZUHIKO
IPC: H01F41/10
Filed: 2018-02-05
Abstract: To provide a coil component that contributes to improvement of a bonding state of a wire while suppressing corrosion of an electrode.SOLUTION: An Ag layer 71 constituting an electrode of a coil component is covered by a Cu plating layer 72, a Ni plating layer 73, and a Sn plating layer 74 in this order. Lead-out sections 51a, 51b, 52a, 52b of a wire are brought into contact with the Cu plating layer 72.SELECTED DRAWING: Figure 6
Patent JP-2018127210-A (JP)
Title: Rim of wheel with tire or supporting and fastening unit for wheel with tire
Inventor: TULLIO GONZAGA
IPC: B60C25/135
Filed: 2018-02-06
Abstract: PROBLEM TO BE SOLVED: To provide a rim of a wheel with a tire or a new supporting and fastening unit for a wheel with a tire.SOLUTION: The invention relates to a rim of a wheel with a tire or a supporting and fastening unit for a wheel with a tire. The unit comprises: a base (2); a wheel holding base part (3); a vertical member or a column part (4) which protrudes upward from the base (2) and supports the wheel holding stand part (3) by an upper part; a shaft or a pin (5) which is installed into or along the vertical member or the column part (4); a sleeve member or a ring nut member (7) which can be confined or attached to the shaft or the pin (5); and means (6) for moving the shaft or the pin (5) relative to the stand part (3).SELECTED DRAWING: Figure 1
Patent JP-2019140449-A (JP)
Title: Imaging apparatus, control method and control program
Inventor: FUKAZAWA TAKAHIKO
IPC: G03B15/00
Filed: 2018-02-07
Abstract: To provide an imaging apparatus, control method and control program which allow a user to discover a prescribed detection object easily.SOLUTION: An imaging apparatus 1 has a body 10, an image generating section 13 placed on one side of the body 10, and generating an input image, a display section 14 placed on the other side of the body and displaying the input image, a detector 172 for detecting a prescribed detection object from the input image, and an image generation control section 171 for controlling the display section 14 to display the position of the image generating section 13 viewed from the display section 14 side, when the detector 172 does not detect the detection object even after elapsing a first prescribed time, the image generating section 13 is placed at a position other than the center of the display section 14, when viewed from the display section 14, and when the detector 172 does not detect the detection object even after elapsing a second prescribed time longer than the first prescribed time, a display control section 173 controls the display section 14 to display an assumed position or an assumed direction of the detection object.SELECTED DRAWING: Figure 6
Patent JP-2018142534-A (JP)
Title: Battery and battery manufacturing method
Inventor: HONDA KAZUYOSHI
IPC: H01M10/0585
Filed: 2018-02-16
Abstract: PROBLEM TO BE SOLVED: To solve the problem that it is desirable to enhance strength of joint between members constituting a battery in a conventional technology.SOLUTION: A battery comprises a first power collecting body, a first electrode layer and a first counter electrode layer. The first counter electrode layer is counter to the first electrode layer, and the first power collecting body has a first surface region, a first backside region, a second surface region, a second backside region and a first bent part. The first backside region is a region positioned at a backside of the first surface region, and the second backside region is a region positioned at a backside of the second surface region. The first bent part is positioned between the first surface region and the second surface region. The first power collecting body is bent at the first bent part, so that the first backside region and the second backside region are positioned to oppose to each other. The first electrode layer is arranged to be brought into contact with the second surface region, and the first counter layer is arranged to be brought into contact with the first surface region.SELECTED DRAWING: Figure 1
Patent JP-2018087229-A (JP)
Title: Pharmaceutical composition
Inventor: HANIUDA Hiroki
IPC: A61K47/32
Filed: 2018-02-16
Abstract: PROBLEM TO BE SOLVED: To provide an ophthalmologic disease therapeutic agent and the like, containing a vascular endothelial growth factor (VEGF) receptor inhibitor or an epithelium growth factor (EGF) receptor inhibitor, in the form of nanoparticles.SOLUTION: The present invention provides an ophthalmologic disease therapeutic agent, containing a vascular endothelial growth factor (VEGF) receptor inhibitor or an epithelium growth factor (EGF) receptor inhibitor, having the nature of building up in the retral ocular tissue when systemically administered, in the form of nanoparticles.SELECTED DRAWING: None
Patent JP-2019143512-A (JP)
Title: Valve mechanism for engine
Inventor: IETANI TOSHIAKI
IPC: F01P3/02
Filed: 2018-02-19
Abstract: To provide a valve mechanism for an engine which improves removability of a core after casting of a cylinder head and achieves improvement of cooling effect of a suction/exhaust valve and downsizing of the cylinder head.SOLUTION: A valve mechanism 10 for an engine includes: a valve guide 12 having a body part 12a in which a guide hole for passing a valve stem 11b of a suction/exhaust valve 11 is formed at its axis and which extends in an axial direction, and a diameter expansion part 12b which is formed at a part of an outer peripheral surface of the body part 12a so that its diameter expands in a radial outer direction; and a cylinder head 16 having a water chamber 22 formed with an opening 23 which is closed by the diameter expansion part 12b. The body part 12a forms the valve mechanism 10 for the engine which faces the water chamber 22.SELECTED DRAWING: Figure 1