baber/WOPTO huggingface dataset:
Patent NZ-715253-A (NZ)
Title: Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
Inventor: RABOISSON PIERRE JEAN-MARIE BERNARD
IPC: A61P31/00
Filed: 2014-07-25
Abstract: Inhibitors of HBV replication of Formula (IA), including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X and R1 to R6 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in hepatitis B therapy.
Patent NZ-731297-A (NZ)
Title: Cd3 binding polypeptides
Inventor: TAN PHILIP HUAT
IPC: A61K39/395
Filed: 2013-04-18
Abstract: The present invention relates to mono-specific and multi-specific polypeptides that specifically bind or interact with CD3. These polypeptides can be, but are not limited to, antibodies, fragments thereof, scFvs, Fabs, di-scFvs single domain antibodies, diabodies, dual variable domain binding proteins and polypeptides containing an antibody or antibody fragments. In one embodiment, a multi-specific polypeptide binds both a T-cell receptor complex on T-cells and a tumor antigen to induce target-dependent T-cell cytotoxicity, activation and proliferation. In a further embodiment, the present invention relates to a CD3 binding polypeptide comprising a CD3 binding domain, wherein the CD3 binding domain has a reduced isoelectric point by at least 0.25 units as compared to the isoelectric point of the binding domain with the amino acid sequence of SEQ ID NO:41; wherein the CD3 binding domain comprises a humanized VH region and a humanized VL region, wherein the humanized VH region and the humanized VL region comprise framework regions; and wherein the VH region comprises SEQ ID NO:28, and the VL region comprises SEQ ID NO:34 or an amino acid sequence from 90% to less than 100% identical to SEQ ID NO:34; and wherein the VL region comprises a CDR1 having a sequence of SEQ ID NO: 52, a CDR2 having a sequence of SEQ ID NO: 53, and a CDR3 having a sequence of SEQ ID NO: 54.
Patent NZ-737584-A (NZ)
Title: Sequence of levels in buildings to be evacuated by elevator systems
Inventor: TROESCH FLORIAN
IPC: H04W4/33
Filed: 2016-07-26
Abstract: During an evacuation situation in a building (2) equipped with an elevator system (1) in which building a plurality of fixed point markings (4) is arranged at specified locations, a sequence of levels (L1, L2, L3) to be evacuated is determined, according to which the elevator system (1) services the levels (L1, L2, L3). The sequence depends on the current traffic situations on the levels (L1, L2, L3). The traffic situation is in turn based on the current positions of the mobile devices (10). Said positions are each determined when a mobile device (10) accesses data received from a first fixed point marking (4) on a database (47) in which the data is linked to a location of the first fixed point marking (4).
Patent NZ-740080-A (NZ)
Title: Biocidal mixtures
Inventor: UHR HERMANN
IPC: C08F12/00
Filed: 2016-08-31
Abstract: The invention relates to biocidal mixtures containing polymer particles containing penflufen, copper compounds and special alkanol amines and to the use thereof for protecting wood and wood products, and wood protection means containing biocidal mixtures and optionally other active substances.
Patent NZ-740587-A (NZ)
Title: Fluoroindole derivatives as muscarinic m1 receptor positive allosteric modulators
Inventor: NIROGI RAMAKRISHNA
IPC: C07D417/14
Filed: 2016-07-19
Abstract: The present invention relates to compound of formula (I), or stereoisomers and pharmaceutically acceptable salts as muscarinic M1 receptor positive allosteric modulators. This invention also relates to methods of making such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to muscarinic M1 receptor.(Formula I) (I)
Patent NZ-743040-A (NZ)
Title: Bioprocessing
Inventor: MEDOFF MARSHALL
IPC: C13K1/02
Filed: 2010-05-18
Abstract: A saccharification mixture comprising: a cellulosic substrate; a microorganism and/or enzyme; a liquid medium; and an inorganic material, such as clay, in the form of particles or fibers, having polar functional groups, complementary to polar functional group on the microorganism or enzyme.
Patent NZ-745703-A (NZ)
Title: Treatment of autoimmune diseases with combinations of rxr agonists and thyroid hormones
Inventor: CHANDRARATNA ROSHANTHA
IPC: C07C57/50
Filed: 2016-10-31
Abstract: The present specification provides methods of treating autoimmune diseases with a combination of a RXR agonist and a thyroid hormone.
Patent NZ-750260-A (NZ)
Title: Antitumor agent and antitumor effect enhancer
Inventor: OKABE HIROYUKI
IPC: A61P35/00
Filed: 2014-09-05
Abstract: Provided is a novel method for treating a cancer using an FTD/TPI combination drug, which shows remarkably excellent antitumor effect. An antitumor agent, in which a combination drug containing trifluridine and tipiracil hydrochloride at a molar ratio of 1 : 0.5 and an anti-VEGF antibody or anti-EGFR antibody are administered in combination
Patent NZ-760006-A (NZ)
Title: Prodrugs of pyridone amides useful as modulators of sodium channels
Inventor: HADIDA-RUAH SARA
IPC: A61K31/675
Filed: 2014-12-12
Abstract: The invention relates to compounds of formula I which are prodrug pyridone amides useful as modulators of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain. The compounds of formula I possess advantageous solubility and physicochemical properties.
Patent NZ-772746-A (NZ)
Title: Body attachment unit for continuous glucose measurement
Inventor: CHAE KYUNG CHUL
IPC: A61B5/15
Filed: 2019-06-07
Abstract: A continuous glucose monitoring body attachable unit comprises a housing containing a bent insertable sensor with a probe for insertion into the body, a battery connected to a PCB, and a wireless communication chip, where the sensor is brought into contact with the spaced apart PCB to initiate operation of the unit. The user can adjust the operation start time to an appropriate point as necessary and the operation can be started in a stabilized state so as to enable more accurate glucose monitoring.
Patent PT-103692-A (PT)
Title: Elemento termoplástico para protecção contra a corrosão
Inventor: ANDERSEN FLORENCIA
IPC: F16L13/02
Filed: 2007-03-19
Abstract: CONSTITUI O OBJECTO DA PRESENTE INVENÇÃO UM ELEMENTO TERMOPLÁSTICO (A) PARA PROTECÇÃO CONTRA A CORROSÃO, NA UNIÃO POR FUSÃO TÉRMICA ENTRE UM TUBO TERMOPLÁSTICO E UMA PEÇA TERMOPLÁSTICA DE CONEXÃO, APRESENTANDO ESTE ELEMENTO O FORMATO DE UMA MANGA TUBULAR COMPLETAMENTE TERMOPLÁSTICA, APROPRIADA PARA SER INTRODUZIDA DENTRO DE UMA EMBOCADURA ALARGADA (E) FORMADA PELA EXPANSÃO DA EXTREMIDADE DO TUBO; ESTE ELEMENTO DE UNIÃO APRESENTA UM ÚNICO DIÂMETRO INTERNO, E DOIS DIÂMETROS EXTERNOS QUE VÃO DEFINIR: (I) UMA PARTE CILÍNDRICA EXTERNA (C) COM MAIOR DIÂMETRO E (II) UMA PROJECÇÃO TUBULAR (C') CUJO DIÂMETRO É MAIS PEQUENO DO QUE O ANTERIOR, A QUAL É INTRODUZIDA DENTRO DO TUBO TERMOPLÁSTICO; UMA PAREDE LATERAL (P) DA PARTE EXTERNA DEFINE UM ENCOSTO FRONTAL DESTE ELEMENTO TERMOPLÁSTICO DE ENCONTRO À EXTREMIDADE (2) DO TUBO TERMOPLÁSTICO. ESTE ELEMENTO DE UNIÃO APRESENTA IGUALMENTE UM ANEL AUXILIAR (C') QUE FUNCIONA COMO UM PONTO DE REFERÊNCIA PARA A RESPECTIVA MONTAGEM.
Patent PT-117291-A (PT)
Title: Viseira de proteção individual ventilada
Inventor: FERNANDO DOMINGUES MOITA
IPC: A41D13/11
Filed: 2021-06-17
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM EQUIPAMENTO DE PROTEÇÃO INDIVIDUAL, NOMEADAMENTE A UMA VISEIRA DE PROTEÇÃO INDIVIDUAL PARA USO EM MÁS ATMOSFERAS. ESTE EQUIPAMENTO COMPREENDE UM CHASSI PRINCIPAL (1) QUE INCORPORA TODOS OS COMPONENTES ELETRÓNICOS NECESSÁRIOS PARA O CORRETO FUNCIONAMENTO DA INVENÇÃO. ESTES COMPONENTES ELETRÓNICOS GARANTEM O DESEMBACIAMENTO DE UMA VISEIRA (8) DE PROTEÇÃO E AUMENTA O CONFORTO QUANDO É USADA EM SIMULTÂNEO COM UMA MÁSCARA DE PROTEÇÃO INDIVIDUAL DEVIDO À REFRIGERAÇÃO GERADA PELO VENTILADOR. O AR VENTILADO, QUE É FILTRADO, GARANTE A SEGURANÇA DO UTILIZADOR. O CHASSI PRINCIPAL (1) APRESENTA ACOPLADO UMA TAMPA (2) QUE PROTEGE OS COMPONENTES ELETRÓNICOS, UM DIFUSOR DE AR (3), UM CHASSI DO FILTRO (4) PARA COLOCAÇÃO DE UM FILTRO DE PARTÍCULAS (5) E UM ELÁSTICO (7) FIXO POR COMPONENTES DE FIXAÇÃO DO ELÁSTICO (6).
Patent RO-79045-A (RO)
Inventor: ORIOL ANDRE
IPC: B61K7/04
Filed: 1980-02-18
Abstract: 1. A track brake for railway carriages and trucks, comprising jaws and operating by gravity, of the type comprising pairs of articulated levers (1, 2) carrying two braking shoes (4) forming jaws disposed on each side of a vertically mobile running rail (3), characterized in that the levers (1, 2) are provided with tenons (5) articulated in housings serving as bearings formed by a two-part movable flange (6) fixed to the base of the running rail (3) without it being necessary to machine the latter, the hook shape of this flange (6) being adapted to retain the tenons (5) of each of the levers (1, 2) in the angle constituted by the web of the rail and its base, and in that the running rail (3) receiving said levers (1, 2) is constituted by one of the two rails of the running track, previously released from the sleepers by removal of the sleeper screws.
Patent RU-94023369-A (RU)
Inventor: LOGINOV E G
IPC: A61J1/03
Filed: 1994-06-20
Abstract: FIELD: medical equipment. SUBSTANCE: device can be used for delivery of tablets in nonstationary conditions. It represents a vial containing one kind of tablets and closed with plug. Located in upper part of plug are two isolated compartments with different kinds of tablets. Sufficiently tightly put over plug is cap. Plug has cylindrical passage with rectangular outlet which connects it with interior of vial, it also has two cutouts, and cap has three cutouts. To deliver required kind of tablets, cap is turned on plug so as to match corresponding pairs of cutouts (rectangular outlet) to remove needed tablets (or their parts if provided). EFFECT: high efficiency. 2 dwg
Patent RU-94024869-A (RU)
Inventor: FEDCHISHIN V G
IPC: F03D7/06
Filed: 1994-07-01
Abstract: FIELD: wind power engineering. SUBSTANCE: each load- carrying cantilever is connected with the housing of the rotor from one side to permit rotation. The other side of the cantilever is connected with the casing of the working gear of the blade by way of hinges and locking members. Being collapsed, all cantilevers and blades are arranged compactly over the periphery parallel to each other. EFFECT: improved design. cl, dwg
Patent RU-94027492-A (RU)
Inventor: TISHENIN JU V
IPC: H01B17/02
Filed: 1994-07-20
Abstract: FIELD: electrical engineering. SUBSTANCE: invention refers to high-voltage polymer insulators. Polymer insulator includes rod of electric insulation material, crack-resistant shell, metal end terminals and screen put inside shell. One of side surface of screen has semi-conductive layer. It is proposed to install screen in face part of insulator so that its butt part is positioned between rod and end terminal. Screen is manufactured from fibrous material impregnated with compound. Height of screen may be chosen from ratio 1.2-4.0 height of end terminal. Screen may be produced in the form of turns of glass bundle impregnated with thermally reactive compound. EFFECT: increased operational reliability due to high electric and mechanical strength.
Patent RU-94029723-A (RU)
Inventor: PESHKIN A F
IPC: G03C1/035
Filed: 1994-08-08
Abstract: FIELD: chemical-photography industry. SUBSTANCE: method involves the silver halides nucleation by two-jet addition silver nitrate and potassium bromide or a mixture of potassium bromide and iodide solutions to oxidized gelatin solution at constant pBr 0.8-2.4, initial pH 3.0-6.0 and temperature 20-45 C. Then nonxidized gelatin is added to the prepared 5-100% emulsion at the weight ratio nonoxidized gelatin : oxidized gelatin = (60-90):(40-1) followed by Ostwald maturation for 10-120 min, at pH 6.0-9.0, rBr value increase by 0.4-2.0 to value 1.2-2.8 at temperature by 5-65 C to 45-85 C. Crystals were grown by two-jet addition off silver nitrate and potassium bromide or a mixture of potassium bromide and iodide solutions to emulsion at pBr 1.2-2.8 and temperature 45-85 C. After termination of microcrystal growth additional growing lateral shell on crystals can be carried out by two-jet addition of silver nitrate and potassium bromide and/or a mixture of potassium bromide and iodide solutions to emulsion. Halide solution is added as 1-6 portions at concentration change of potassium iodide and total halide amount in every following portion by 2-28 and 2-12 mole%, respectively. Prepared emulsions contain microcrystals of the following indices: mean diameter d = 0.3-4.0 mcm, mean thickness h = 0.03-0.10 mm, d : h = 8-55, variation coefficient C = 10-20%, yield of hexagonal microcrystals is 90-93%. EFFECT: improved method of emulsion preparing. 2 tbl
Patent RU-94029802-A (RU)
Inventor: BULGAKOV D S
IPC: B22D11/04
Filed: 1994-08-09
Abstract: FIELD: devices for continuous casting of metals and alloys. SUBSTANCE: continuous-casting mould uses sleeve 1, casing 2 with cylindrical bosses 3 installed in body 4, cooled slotted duct 5 between the sleeve and casing, chamber 6, cover 7 and ducts 8 and 9 for discharge of water-air mixture made in body 4 and casing cylindrical boss respectively, water and air supply manifolds 12 and 13 respectively, vertical water and air supply pipe connections 14 and 15 respectively, device 16 for water- air mixture, having chambers for water and air supply, water supply ducts and a Laval nozzle, mixing chamber 21, diffuser 22 conjugate to the cooled slotted duct at an angle of 90 to 100 deg., and vertical water and air supply pipe connections 23 and 24 respectively. All ducts of the water-air device components have a square section by 0.6 to 0.8 of the width of each sleeve face; the mixer chamber and diffuser are located in the detachable part of the mould; the duct for discharge of water-air mixture is made in the upper boss of the casing by 1.1 to 1.2 of the diffuser outlet-section area, the mixing chamber length equals: 1 cm=(4 to 6)h, where h - mixing chamber height, and diffuser length ld.=(6 to 7)(H-h), where H - mould outlet-section height, the upper plane of the diffuser is chamfered up at radius(H-h). EFFECT: enhanced resistance of the mould and simplified design, enhanced efficiency of cooling, improved servicing, no additional expenditures connected with cooling and preparation of circulating water. 3 dwg
Patent RU-94036678-A (RU)
Inventor: KUSHNIKOVA R V
IPC: C09K3/10
Filed: 1994-09-29
Abstract: FIELD: electrical technology. SUBSTANCE: proposed polyurethane insulation compound is prepared by interaction of two reagents. Mixture of castor oil and methyl benzene (their quantities being 59.5-75.2 % and 3.8-23.8 % respectively) is used as the first reagent. 2,4-toluyl(en)-di(iso)cyanate is used as reagent 2. Said interaction is carried out by mixing said reagents within 3-5 min. Additionally peroxide of di(benzoyl) is added, its quantity being 0.5-1.0 %. The process is followed by hardening within 60-80 C. EFFECT: simplifies the method. 2 tbl
Patent RU-94038529-A (RU)
Inventor: NIKITIN A A
IPC: F21V31/00
Filed: 1994-10-12
Abstract: FIELD: lighting engineering. SUBSTANCE: small-sized underwater light has water-tight housing accommodating reflector whose concave reflecting surface is formed by body of revolution (truncated ellipsoid), halogen lamp mounted so that its longitudinal axis is along optical axis of ellipsoid and center of filament body is in first focus of ellipsoid, thermostatic port made of leucosapphire crystal plate whose axis is perpendicular to main optical axis of reflector. Thermostatic port covers face side of housing through sealed joint and is spaced from first focus of ellipsoid through on third to one second of distance between ellipsoid focuses. EFFECT: improved design. 2 cl, 1 dwg
Patent RU-94040261-A (RU)
Inventor: BABINTSEVA N I
IPC: C30B11/10
Filed: 1994-11-01
Abstract: FIELD: crystallography, in particular preparation of crystals using process of horizontal directed crystallization in vacuum. SUBSTANCE: device for growing monocrystals from melt having crystallization cell, heater inside the cell, system controlling tension of heater, system for evacuating crystallization cell with controlling unit, and water cooling system is additionally provided with units for controlling water temperature and water input in the cooling system. Outlets of units controlling evacuation system and water temperature and one of the outlets of unit controlling water output are connected with matched inlets of system controlling tension of heater. The other outlet of water output unit is connected to unit controlling evacuation system. System of water cooling is made as a set of independently controlled circuits of cooling of crystallization cell, evacuation system, and system of controlling tension of heater, each circuit being provided with units controlling water temperature and water output. Preferably circuit of water system of system controlling heater tension consists of at least two independent lines. EFFECT: enhanced automatic performance and reduced water input.
Patent RU-94040390-A (RU)
Inventor: FRANKO BUZZETTI
IPC: A61K31/435
Filed: 1993-12-15
Abstract: FIELD: organic chemistry. SUBSTANCE: invention relates to compounds of the formula (I)where: one of groups X-Xmeans N and others mean CH; R means the group of the formula (a), (b), (c), (d)or (e)where: n = 0-5; Rmeans hydrogen, halide, C-C-alkyl, C-C-alkoxy, nitro or the group of the formula -NRRwhere each Rand Rmeans independently hydrogen or C-C-alkyl; Rmeans hydrogen, C-C-alkyl or C-C-alkanoyl; Rmeans hydrogen, halide, hydroxy, C-C-alkoxy, carboxy, nitro or the group -NRRwhere Randmean values given above, and their pharmaceutically acceptable salts. Compounds of the formula (I)can be used as inhibitors of tyrosine kinase. EFFECT: improved method of synthesis.
Patent RU-94042329-A (RU)
Inventor: NOVOSELOV A L
IPC: F01N3/28
Filed: 1994-11-30
Abstract: FIELD: engine manufacture; cleaning of engine exhaust gases from detrimental components and soot. SUBSTANCE: neutralizer has oval-section case, end plate, inlet and outlet pipe connections, case internal partitions, catalytic reactor whose inner space is formed by inner surfaces of end wall, end plate, and reactor walls. Reactor space accommodates holding guides in the form of swirlers and filters one of which is made of cermet material to trap hard particles and to completely burn them on surface in catalytic agent environment; other filter is placed inside cermet filter and made in the form of finned radiator held in position by means of its own fins. Inlet pipe connection houses oxygen sensor; cermet filter is placed in catalytic gauze shell. EFFECT: reduced emission of pollutants; improved heat economic efficiency due to reduction of resistance at exhaust end; reduced exhaust noise.
Patent RU-94043167-A (RU)
Inventor: VAJLER N I
IPC: B28B19/00
Filed: 1994-11-30
Abstract: FIELD: methods of material guniting on surface to form solid layer on them, method is used for formation of thin-layer and facing coatings in building, gas and oil industry, hydraulic-engineering and other branches of industry. SUBSTANCE: temperature and parameters of applied on piece surface wet cement-sand mixture are corrected by value of intensity of heat feeding from applied mixture into piece. EFFECT: improved control over guniting process. 1 dwg
Patent RU-94045257-A (RU)
Inventor: MAENFISH PETER
IPC: C07C323/37
Filed: 1994-12-28
Abstract: FIELD: organic chemistry. SUBSTANCE: product: compound of the formulawhere: R- C-C-cycloalkyl, haloid-C-C-cycloalkyl,C-C-cycloalkyl-C-C-alkyl,haloid-C-C-cycloalkyl-C-C-alkyl, Si(R), -S-R, -SO-Ror -CO-R; R- halogen, C-C-alkyl or CFbeing Rcan be similar or different when n = 2; R- each independently of other is C-C-alkyl, haloid-C-C-alkyl, C-C-alkoxy or phenyl; R- aryl or heteroaryl each of which can be free or substituted; R- free of substituted C-C-alkyl, C-C-alkenyl, C-C-alkynyl, C-C-alkoxy, C-C-alkenylhydroxy, C-C-alkynylhydroxy, C-C-alkylthio, aryl, arylhydroxy or arylthio or optional substituted amino-group; R- hydroxy, free or substituted C-C-alkyl, C-C-alkenyl, C-C-alkynyl, C-C-cycloalkyl, aryl or arylhydroxy or optional substituted amino-group; R- hydrogen or free or substituted C-C-alkyl; m = 1, 3, 5, 7, 9 or 11; n = 0, 1 or 2; X - fluorine or chlorine; and Y - hydrogen, fluorine or methyl. Synthesized compounds as free form or as salts can be used as pesticides and obtained by method. EFFECT: improved method of synthesis.
Patent RU-95102530-A (RU)
Inventor: GLUMOV I F
IPC: E21B43/22
Filed: 1995-02-21
Abstract: FIELD: oil producing industry, particular, oil recovery from nonuniform formations with performance of isolating jobs for equalization of injectivity profile of injection wells and reduction of water inflow in producing wells with the help of visco-elastic compounds based on polyacrylamide. SUBSTANCE: the offered method includes successive injection into formation of solutions of polyacrylamide and aluminium salt. Injected between fringes of polyacrylamide and aluminum salt is fringe of sweet water, whose volume is determined by the equation offered in the invention description. Solution of surfactants is injected into formation with concentration determined by the equation offered in the invention description. EFFECT: provision of regulation of time taken for gel formation in formation and reduced mechanical and salt destruction of polyacrylamide.
Patent RU-95102673-A (RU)
Inventor: BOBROV N N
IPC: B01F3/04
Filed: 1995-02-28
Abstract: FIELD: instrumentation engineering. SUBSTANCE: invention relates to manufacture of equipment for continuous physico-chemical experiments in laboratories, in particular, to a device for saturating gas streams with vapors of an one-component liquid kept at a constant temperature. Device of invention provides, on its outlet, vapor-gas mixtures with equilibrium concentration of vapor of the liquid corresponding to partial pressure of the vapor at controlled temperature of the liquid. Saturator has cylindrical vessel with liquid, thermostat for the vessel, submerged gas-intake pipe with opened lower end, vapor-gas mixture discharge pipe, liquid-intake pipe, fully submerged upright coil with its lower end connected to gas-intake pipe and open upper end reaching the level 3-5 mm below the liquid surface level. Lower end of gas-intake pipe below the point where it is connected with coil has an organized space opened from below into the liquid at a distance 1-2 cm from bottom. Saturator is further provided with a system for automatically maintaining liquid level in cylindric vessel. EFFECT: provided perseverance in vapor-gas ratio when varying gas intake in saturator.
Patent RU-95104564-A (RU)
Inventor: ANTONOV V M
IPC: A21D13/02
Filed: 1995-03-30
Abstract: FIELD: food industry. SUBSTANCE: method involves steeping wheat grain, its steeping, preparing grain material, grinding it by cutting and breaking, and extruding in system knife-die, and introducing components in grain material. Dough kneading is carried out by impulse mechanical action on dough, fermenting, making-up and baking. Used as a component rye grain is introduced after its steeping and grinding by cutting and breaking, and extruding in system knife-die. Rye grain is steeped for 2-20 h. Ratio between wheat and rye grain is 1-(0.05-2). EFFECT: higher efficiency.