baber/WOPTO huggingface dataset:
Patent CA-3083941-A1 (CA)
Inventor: HIGGINSON-SCOTT NATHAN
IPC: A61P29/00
Filed: 2018-11-28
Abstract: Described herein are therapeutics that can modulate (e.g. increase) T-reg cell proliferation, survival, activation and/or function. In some embodiments, the modulation is selective or specific for the T-reg cells. The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same. In another aspect, the present embodiments provide compositions, e.g., pharmaceutically acceptable compositions, which include a therapeutic compound (IL-2 mutein) described herein, formulated together with a pharmaceutically acceptable carrier. Also within the scope of the invention is a kit comprising a therapeutic compound described herein.
Patent CA-3084439-A1 (CA)
Inventor: LOVE J CHRISTOPHER
IPC: G03F7/00
Filed: 2018-12-07
Abstract: La présente invention concerne des améliorations apportées à la fois au matériel et aux réactions enzymatiques utilisées dans des analyses de cellules simples telles que, mais sans s'y limiter, l'analyse Seq-well permettant des augmentations significatives du rendement de produits de transcription par cellule, une portabilité et une facilité d'utilisation améliorées, une extensibilité accrue du dosage, et une liaison d'informations de transcription à d'autres mesures effectuées dans les réseaux de picopuits.
Patent CA-3086087-A1 (CA)
Inventor: O'NAGY OLIVER
IPC: G01W1/14
Filed: 2018-12-18
Abstract: The present application relates to a freezing precipitation detection device (10) comprising at least one first wetness detection means (1) in thermo-conducting contact with the upper (3A) surface of a sloped thermo-conducting sheet (3), at least one second wetness detection means (2) in thermo-conducting contact with the lower (3B) surface of said sloped thermo-conducting sheet (3), at least one surface temperature detection means (4) in thermo-conducting contact with said sloped thermo-conducting sheet (3), at least one processor (5) configured to receive at least one first signal (11; 11A, 11B,11C) from the first wetness detection means (1) and from the second wetness detection means (2) and from the surface temperature detection means (4), analyzing said first signal (11; 11A, 11B, 11C) and determining the presence or the absence of a freezing precipitation on the surface of the sloped thermo-conducting sheet (3), at least one first apparatus (7) for external power relay receiving at least a second signal (12) from the processor (5), said signal being indicative of a recommended action by said first apparatus (7), said action being either permitting to provide power or not to provide power to at least one third apparatus (8), at least one second apparatus (6) for power supply being connected to said processor (5) and also to said first apparatus (7), wherein said second apparatus (6) for power supply is not actively heating said thermo-conducting sheet (3), said first apparatus (7) permitting to provide power to said third apparatus (8) only when said surface temperature detection means (4) detects a temperature less or equal to a determined threshold and the first and second wetness detection means (1; 2) detect the presence of a freezing precipitation. The present invention relates also to uses and a method for detecting a freezing precipitation.
Patent CA-3086230-A1 (CA)
Inventor: FIGUEIREDO EROL
IPC: B64D29/08
Filed: 2018-12-17
Abstract: A servicing panel of an aircraft accessible from an exterior of the aircraft is disclosed. The servicing panel comprises an electronic display device having a display area viewable from the exterior of the aircraft. The electronic display device is operatively connected to display information relating to one or more systems of the aircraft on the display area.
Patent CA-3086771-A1 (CA)
Inventor: GEHO W BLAIR
IPC: A61P3/10
Filed: 2019-01-07
Abstract: CA 03086771 2020-06-23 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property AllIEHEINHEEHRIOHNIEMENIMMOMN Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2019/136386 Al 11 July 2019 (11.07.2019) WIPO I PCT (51) International Patent Classification: SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, A61K 9/51 (2006.01) A61K 38/28 (2006.01) TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. A61K 8/11 (2006.01) A61K 47/28 (2006.01) (84) Designated States (unless otherwise indicated, for every A61K 9/127 (2006.01) A61P 3/10 (2006.01) kind of regional protection available): ARIPO (BW, GH, (21) International Application Number: GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, PCT/U52019/012557 UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (22) International Filing Date: EE, ES, FI, FR, GB, GR, HR, HU, EE, IS, IT, LT, LU, LV, 0'7 January 2019 (0'7.01.2019) MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (25) Filing Language: English TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (26) Publication Language: English (30) Priority Data: Declarations under Rule 4.17: 62/614,109 05 January 2018 (05.01.2018) US ¨ of inventorship (Rule 4.17(iv)) (71) Applicant: SDG, INC. [US/US]; 10000 Cedar Avenue, Published: Suite 6, Cleveland, Ohio 44106 (US). ¨ with international search report (Art. 21(3)) (72) Inventor: GEHO, W. Blair; 533 Beechwood Drive, Wooster, Ohio 44691 (US). (74) Agent: SILVA, Domingos J. et al.; Saul Ewing Arnstein & Lehr LLP, 1500 Market Street, 38th Floor, Philadelphia, Pennsylvania 19102 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (54) Title: COMPOSITIONS COMPRISING LIPED-BASED NANOPARTICLES FOR TREATING DIABETES MELLITUS FIG. I E Insulin Dosage M US HDV HS HDV HS HDV HS HDV US HDV 01,0 p=0.37 twEIA2 NiL 6, MI 4!C g 0.26 !!!! 4t4 \\\ Cie 4682 W -0.0 1111111111111111111 BB re) ....... re) Week 0 Week 243 Week 0 Week 26 Baitis suli asal lnsuHn em, (57) Abstract: The invention provides methods of treating a subject having diabetes mellitus. The invention further provides methods of increasing distribution volume of insulin in a subject. P"'
Patent CA-3092696-A1 (CA)
Title: Communication systems and methods
Inventor: BUSH STEPHEN FRANCIS
IPC: H04L7/00
Filed: 2020-09-10
Abstract: A communication system is provided that include one or more processors that are configured to instruct computing devices that communicate messages with each other via a time-sensitive network to securely exchange the messages using secret information, ad direct the computing devices to exchange the secret information via a dedicated quantum channel in the time-sensitive network. The one or more processors are also configured to determine a quantum channel synchronization time associated with the secret information exchanged via the dedicated quantum channel, and modify a local classical oscillator based on the quantum channel synchronization time, the local classical oscillator configured to provide a current time.
Patent CA-3093100-A1 (CA)
Title: Vehicle floor
Inventor: WONG PETER
IPC: B62D25/20
Filed: 2020-09-15
Abstract: Embodiments disclosed herein relate to a vehicle floor for a vehicle having a length and a width. The vehicle floor comprises a number of sheets of material having a length equal to the length of the vehicle. A joint couples the number of sheets to form a width equal to the width of the vehicle. Also, a method of constructing a vehicle is provided. A length and a width of the vehicle are determined. Material is cut into a first sheet and a second sheet both equal to the length of the vehicle. A joint couples the first sheet and the second sheet to form the width of the vehicle.
Patent CA-3095646-A1 (CA)
Inventor: ALTMAN MICHAEL D
IPC: C07D417/12
Filed: 2019-04-01
Abstract: Compounds of general formula (I), of general formula (II), of general formula (III), of general formula (IV), of general formula (V), of general formula (VI), and their pharmaceutically acceptable salts, wherein all variables are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are compositions comprising such compounds, processes for the synthesis of such compounds, and to uses of such compounds, including administration of such compounds to induce immune response, to induce STING-dependent type I interferon production, and/or to treat a cell proliferation disorder, such as cancer.
Patent CA-3099834-A1 (CA)
Title: Methode de fabrication d'oxyde de graphene a partir de dechets de graphite d'electrode
Inventor: VU THI TAN
IPC: C01B32/194
Filed: 2019-04-10
Abstract: La présente invention concerne une méthode de fabrication d'oxyde de graphène à partir de déchets de graphite d'électrode comprenant la fourniture de déchets de graphite d'électrode, le broyage des déchets de graphite d'électrode pour obtenir une électrode en graphite broyée et une étape d'oxydation de l'électrode en graphite broyée pour obtenir de l'oxyde de graphène.
Patent CA-3101733-A1 (CA)
Title: Automated product locker for inventory control
Inventor: KERNICK EDWARD R
IPC: G06V30/224
Filed: 2020-05-13
Abstract: An example automated product locker is described herein. The automated product locker can include a housing and a drawer configured to be slidably stowable within the housing. The drawer can define a storage area configured to receive a product. The automated product locker can include a plurality of visual indicators configured to indicate respective positions of respective units of the product within the storage area, and a machine vision system configured to capture information about the product. The machine vision system can include an optical device. Additionally, the automated product locker can include a controller operably coupled to the machine vision system. The controller can be configured to inventory the product based, at least in part, on the information about the product, and cause one or more of the visual indicators that are associated with a desired unit of the product to actuate.
Patent CA-3102350-A1 (CA)
Title: Attenuation device for the fluid flow pulsation in a hydraulic circuit connected with a hydraulic machine
Inventor: MORSELLI MARIO ANTONIO
IPC: F16L55/027
Filed: 2019-06-27
Abstract: The present invention concerns an attenuation device (1) of the fluid flow pulsation along a duct of a hydraulic circuit connected with a hydraulic machine, comprising at least an attenuation module (3) passed through by a pass-through duct (5) configured to be placed in fluid communication with said duct of said hydraulic circuit. In particular, in said attenuation module (3) a first duct (7) is obtained having an opened first end (70) in fluid communication with said pass-through duct (5), and a closed second end, said first duct (7) extending along a curved line comprising a plurality of curved sections, said first duct (7) being adapted to attenuate the pulsation of said fluid flow along said duct of said hydraulic circuit to reduce the vibrations generated by said pulsation of said fluid flow.
Patent CA-3106012-A1 (CA)
Inventor: DEFRANKS MICHAEL S
IPC: A47C21/04
Filed: 2014-01-10
Abstract: Il est décrit un système de literie à ambiance contrôlée servant à contrôler la température du corps en vue de permettre à lutilisateur de sendormir rapidement et de maintenir son sommeil pendant de plus longues périodes dans diverses conditions climatiques ambiantes dans lesquelles le système de literie peut se trouver. En général, le système de literie à ambiance contrôlée comprend une base ayant une surface rigide perméable au fluide qui enveloppe une cavité, laquelle surface rigide perméable au fluide est entièrement perméable à lair de sorte quun flux dair montant la traverse. Lappareil constituant une alimentation dair en communication fluidique avec la surface rigide perméable au fluide de la base se dispose à lintérieur de la base. Une couche en mousse perforée recouvre la base et comprend plusieurs conduits verticaux. Une couche de ressorts hélicoïdaux en contact direct avec la surface plane supérieure de la couche en mousse perforée recouvre cette dernière.
Patent CA-3107483-A1 (CA)
Inventor: O'CONNELL DANIEL NEIL
IPC: H02G1/02
Filed: 2021-01-29
Abstract: A spring loaded grounding clamp system uses a strong linear spring force spring driving a piston mounted movable jaw as a safety lockout. The system includes a ground clamp which, when connected to and seated on, the end of a hot stick tool, provides for electrically insulated remote operation of the spring loaded ground clamp by a lineman holding the hot stick tool and pulling on, or releasing, a lever arm on the hot stick tool. The system provides increased safety for the lineman as the spring providing the spring loading of the clamp has a high spring force to overcome, thus providing the lockout. The lever arm on the hot stick tool provides mechanical advantage in order to overcome the spring force and thus release the lockout, and cannot usefully operate the spring loaded ground clamp manually without the hot stick tool.
Patent CA-3108068-A1 (CA)
Inventor: BABKIN ALEXEI
IPC: A61B18/02
Filed: 2019-07-29
Abstract: A cryoablation apparatus for creating a lesion in a target tissue includes an expandable energy transfer region formed of a plurality of independent spline ablation members. Manipulation of a control member extending from a handle to the energy transfer region controllably adjusts the shape of the energy transfer region to contact complex anatomies. A service lumen extending through the length of apparatus can slidably receive an ancillary' catheter such as a guide catheter or diagnostic catheter. The catheter has particular application to treating conditions of the heart. Related methods and systems are also described.
Patent CA-3108925-A1 (CA)
Inventor: FULLENWIDER MARC WESLEY
IPC: E05C7/00
Filed: 2019-09-12
Abstract: An automated sash lock for locking a window sash comprises a linearly depressible trigger, a cam-style locking element normally biased towards a locked position, a rotatable detent actuated by the trigger, a pivotable transfer element between the detent and the locking element, and an actuator for manually operating the lock mechanism to unlock the lock when the window is in a closed and locked position. The detent is normally biased in the direction of the locking element and a portion of the detent engages a body portion of the locking element to maintain the locking element in a retracted position when the window is open. Upon actuation of the trigger by a closing window, the trigger translates linearly into the lock housing and rotates the detent into the disengaged position, pulling the detent away from the locking element and allowing the locking element to fire out of the lock housing and into an opening in a strike in the adjacent sash to prevent the sashes from relative sliding movement.
Patent CA-3109847-A1 (CA)
Title: Accouplements d'arbres pour charges de traction elevees dans des systemes esp
Inventor: MACK JOHN KAY
IPC: F04B47/06
Filed: 2019-09-03
Abstract: L'invention concerne un accouplement d'arbres pour relier un arbre supérieur à un arbre inférieur à l'intérieur d'un système de pompage, ledit accouplement d'arbres étant conçu pour gérer une charge de traction élevée entre les arbres supérieur et inférieur. Dans certains modes de réalisation, l'arbre supérieur comprend une rainure annulaire et l'accouplement présente un corps et une première chambre de réception, située à l'intérieur du corps, qui reçoit une extrémité de l'arbre supérieur. L'accouplement comprend également une rainure interne supérieure s'étendant dans le corps à partir de la première chambre de réception et une bague fendue supérieure qui est configurée pour être comprimée dans une position occupant à la fois la rainure interne supérieure et la rainure annulaire de l'arbre supérieur. Des vis de pression compriment bague fendue supérieure dans la rainure annulaire de l'arbre supérieur. Dans un autre mode de réalisation, l'accouplement comprend une pluralité de vis de blocage qui s'étendent à travers le corps dans des rainures de vis de blocage correspondantes dans les arbres supérieur et inférieur.
Patent CA-3111564-A1 (CA)
Inventor: ESTES JASON
IPC: G06Q50/06
Filed: 2019-10-10
Abstract: A smart sensor group management service may be used to establish groups of smart sensors that are associated with one or more common characteristics, such as a common application associated with the smart sensors. The group management service may establish multiple physical groups per application so that multiple entities may have access to managing the groups. The physical groups may be associated with a virtual group that facilitates management of the physical groups and may be accessible by the entities. The entities may perform different types of management operations using the group management service, such as creating groups, adding smart sensors to groups, removing smart sensors from groups, and adjusting settings of features of the applications that are associated with the groups.
Patent CA-3113310-A1 (CA)
Inventor: BRIESE WILLIAM A
IPC: E06B3/673
Filed: 2011-07-08
Abstract: Method and Apparatus for fabricating elongated window or door components from strip stock including multiple work stations for treating the strip stock as the strip stock moves along a travel path through the multiple work stations.
Patent CA-3114458-A1 (CA)
Title: Biomarqueurs ttg-dgp pour la surveillance de la maladie coeliaque
Inventor: CHOUNG ROK SEON
IPC: G01N33/68
Filed: 2019-10-08
Abstract: La présente invention porte d'une manière générale sur des biomarqueurs et des réseaux de peptides, et plus particulièrement sur un procédé d'utilisation d'un réseau de peptides pour identifier des biomarqueurs pour une maladie auto-immune, telle que la maladie cliaque, par exemple. En outre, l'invention concerne un ensemble de nouveaux biomarqueurs de la maladie cliaque présentant une sensibilité et une spécificité élevées, ainsi qu'une méthode de traitement utilisant les nouveaux biomarqueurs.
Patent CA-3114490-A1 (CA)
Inventor: BRETHE JEAN-FRANCOIS
IPC: F16H21/04
Filed: 2019-09-26
Abstract: The present invention relates to a robotic system, comprising an articulated arm, characterised in that the articulated arm (100) has a deformable assembly consisting of a plurality of bars (1 to 4) connected by parallel pivot axes (10 to 13) to form at least one deformable structure, the distal end (12) of the deformable assembly supporting a mechanical interface, the system further comprising two actuators which rotate two of the bars (1 to 4), the system further comprising a third actuator controlling the translational movement of the deformable assembly in a direction parallel to the pivot axes (10 to 13).
Patent CA-3114506-A1 (CA)
Title: Tape comprising a hybrid binder for high voltage application
Inventor: MURRAY THOMAS JAMES
IPC: C08L63/10
Filed: 2019-10-04
Abstract: The present invention relates to a tape comprising an epoxy based resin having ester groups and ethylenically unsaturated groups, alternatively a hybrid resin. The tape of the invention can be used for insulation in electrical machines, especially in high voltage machines. Preferably, the tape of the invention is used in combination with a composition for impregnating and/or coating a substrate comprising the tape of the invention, wherein the composition further comprises a second epoxy based resin having ester groups and ethylenically unsaturated groups, also an hybrid resin, a diluent and an initiator for a radical polymerization.
Patent CA-3115095-A1 (CA)
Title: System and method for intrauterine insemination
Inventor: PLESSALA KIRBY
IPC: A61B17/43
Filed: 2019-10-10
Abstract: A kit and method for intrauterine insemination is provided. The steps of the method include self-monitoring of a menstrual cycle of a patient by said patient, making an abrasion on the endometrial lining of a uterus of the patient following menstruation by the patient, predicting timing of ovulation by using an ovulation monitoring system or inducing ovulation; preparing sperm for insemination during ovulation by the patient, guiding an intrauterine insemination catheter accompanied by a cervical shield into the patient, depositing a semen sample into the uterine cavity or cervical canal, removing the catheter from the body of the patient while using a holding tool to hold the cervical shield in place at the entrance to the uterine cavity, and leaving the cervical shield in place for a predetermined time period.
Patent CA-3115474-A1 (CA)
Inventor: HOGAN MARK PAUL
IPC: B65D53/08
Filed: 2021-04-16
Abstract: A cover sheet 1 to be secured to the tray of a container is described. The cover sheet 1 comprises a first layer 2 and a second layer. An adhesive layer is provided between the first and second layers. The first layer 2 has a first cut line 8 that extends across a corner of the cover sheet between a first edge 6a and a second edge 6b to define a tab portion 10 of the first layer. The second layer has a second cut line that extends from the first edge 6a to the second edge 6b or a third edge 6c to define a removable strip of the second layer. Removing the removable strip and the adhered tab portion 10 exposes the adhesive layer on a securing portion of the first layer 2 that can be used to secure the cover sheet to the tray.
Patent CA-3115770-A1 (CA)
Inventor: SCHAAL JUSTIN B
IPC: A61K47/10
Filed: 2019-10-09
Abstract: Compositions are provided for formulations of ?-defensin and/or a ?-defensin analog that are highly suitable for parenteral administration. Such formulations provide the ?-defensin and/or a ?-defensin analog in a slightly acidic buffer that includes propylene glycol. Surprisingly, Inventors have found that such formulation increase bioavailability of a ?-defensin and/or a ?-defensin analog so provided by at least a factor of 10 relative to conventional isotonic saline solutions, and that such formulations dramatically improved bioavailability in human subjects relative to animal models. Inventors have also found that such formulations advantageously exhibit low viscosity at high peptide concentrations, reducing injection volume permitting sterilization by simple filtration.
Patent CA-3116456-A1 (CA)
Title: Novel chemiluminescent substrates for factor xa
Inventor: VAN HEERDE WAANDER LAURENS
IPC: C07D277/68
Filed: 2019-10-17
Abstract: The present invention relates to chemiluminescent substrates of formulas (I-3) and (I-4) for blood clotting enzyme Factor Xa. The substrates are particularly useful for assaying coagulation factors and for quantifying an anticoagulant in a sample.
Patent CA-3116558-A1 (CA)
Title: Guidewire locking device
Inventor: MANSFIELD RICHARD P
IPC: A61B1/012
Filed: 2019-10-16
Abstract: A medical device is provided. The device includes a body that includes an opening through which a wire is configured to extend. The body further includes an edge and a skirt having only three surfaces surrounding the opening and extending further downwardly in a direction away from the opening than the edge.