baber/WOPTO huggingface dataset:
Patent CA-2415058-A1 (CA)
Title: Pharmaceutical compositions of estrogenic agents
Inventor: SURYAWANSHI JIWAJI GULABRAO
IPC: A61K47/36
Filed: 2001-06-29
Abstract: This invention comprises novel pharmaceutical carrier or excipient systems and oral pharmaceutical formulations comprising as an active ingredient raloxifene, amoxifen, droloxifene, arzoxifene, or CP 336156, or analogs thereof, or a compound of formulae (I) or (II), wherein Z is a moiety selected from the group of formulae (a, b or c), wherein: R¿1? is selected from H, OH or the C¿1?-C¿12? esters alkyl ethers thereof, benzyloxy, or halogen; or C¿1?-C¿4? halogenated ethers; R¿2?, R¿3?, R¿4?, R¿5?, and R¿6? are H, OH or C¿1?-C¿12? esters or alkyl ethers thereof, halogens, or C¿1?-C¿4? halogenated ethers, cyano, C¿1?-C¿6? alkyl, or CF¿3?, with the proviso that, when R¿1? is H, R¿2? is not OH; Y is the moiety:formulae (d), wherein R¿7? and R¿8? are alkyl or concatenated together to form an optionally substituted, nitrogen-containing ring; or a pharmaceutically acceptable salt thereof; and excipients chosen from pharmaceutical fillers, glidants, lubricants, wetting agents and antioxidants.
Patent CA-2416285-A1 (CA)
Inventor: SUN YONGMING
IPC: A61P35/00
Filed: 2001-07-17
Abstract: L'invention concerne des procédés de détection, de diagnostic, de contrôle, de détermination du stade, de prévision, d'imagerie, et de traitement du cancer du colon.
Patent CA-2416469-A1 (CA)
Title: Fork lift tine receiving member for use with a bulk bag having underlying straps
Inventor: BAKER GERALD LYNN
IPC: B65D88/16
Filed: 2003-01-16
Abstract: This fork lift tine receiving member was developed for use with a bulk bag having underlying straps. The fork lift tine receiving member includes a tubular body having a peripheral sidewall. There is at least one opening in the sidewall. At least one flap extends into the opening. The flap is integrally formed from and co-planar with the sidewall. The flap has a first side edge and a second side edge. The opening has a first slotted portion extending through the sidewall adjacent the first side edge and a second slotted portion extending through the sidewall adjacent the second side edge. When in use, a strap is extends through the first slotted portion, under the flap and through the second slotted portion.
Patent CA-2417173-A1 (CA)
Inventor: OFOSU-ASANTE KOFI
IPC: D06M16/00
Filed: 2001-08-17
Abstract: L'invention concerne des procédés de sélection et de traitement d'un vêtement au moyen d'une composition de rafraîchissement, de désodorisation et de finition, permettant d'améliorer différentes propriétés des vêtements, notamment, la réduction ou l'élimination de faux plis indésirables, d'odeurs et analogue. L'invention concerne également un article fabriqué renfermant une pluralité de compositions de rafraîchissement, de désodorisation et de finition dans une pluralité de contenants jetables comprenant des modes d'emploi permettant de les utiliser dans un appareil.
Patent CA-2420086-A1 (CA)
Inventor: FRIEDE MARTIN
IPC: A61K38/095
Filed: 2001-08-17
Abstract: La présente invention concerne un nouveau procédé chimique permettant la conjugaison covalente de peptides cyclisés par ponts bisulfure à des molécules de support immunogène par des liaisons thio-éther pour former des vaccins immunogènes. En particulier, ce nouveau procédé chimique consiste à faire réagir un support thiolé avec un peptide cyclique contenant un pont bisulfure. Ledit peptide cyclique (dans le cas présent un peptide cyclisé par pont bisulfure) présente, relié à lui, habituellement par un lieur, un groupe réactif pouvant former des liaisons thio-éther avec le support. L'invention concerne également des produits intermédiaires de peptides activés, des médicaments obtenus selon le procédé, des compositions pharmaceutiques contenant ces médicaments, et l'utilisation de ces compositions pharmaceutiques en médecine. Le procédé de la présente invention est particulièrement utile pour la préparation d'immunogènes de grande pureté pour des vaccins, y compris de peptides cyclisés par ponts bisulfure. L'invention concerne également de nouveaux immunogènes, obtenus à partir de peptides dérivés de la séquence de l'immunoglobuline E humaine, utiles dans l'immunothérapie de l'allergie. En conséquence, l'invention concerne également un procédé permettant la conjugaison de peptides cyclisés par ponts bisulfures de l'immunoglobuline E à des supports, des immunogènes obtenus selon le procédé, des vaccins et des compositions pharmaceutiques qui les comprennent, ainsi que leur utilisation dans le traitement de l'allergie.
Patent CA-2421324-A1 (CA)
Title: Mutant non-human mammal for expressing the alpha6 acetylcholine nicotinic receptor subunit and use for screening substances capable of interacting with said receptor
Inventor: CHAMPTIAUX NICOLAS
IPC: A01K67/027
Filed: 2001-09-04
Abstract: The invention concerns a non-human mammal bearing a mutation in the gene encoding the alpha6 acetylcholine nicotinic receptor (nAChR) subunit, said mutation preventing the expression in the mammal of said alpha6 nAChR subunit in functional form. The invention also concerns preparations of synaptosomes obtained from said animals and cell cultures obtained by mutation of the alpha6 subunit described above.
Patent CA-2423767-A1 (CA)
Inventor: PRUD HOMME REGIS
IPC: A01L7/04
Filed: 2003-03-28
Abstract: A horseshoe with spikes and a method for making the spikes. The horseshoe has a ground engaging surface provided with first and second series of substantially parallel V-shaped grooves. The first series of substantially parallel V-shaped grooves define a first series of axes and the second series of substantially parallel V-shaped grooves define a second series of axes intersecting the first series of axes at an angle, thereby defining a plurality of pyramid-like spikes on the at least one portion of the ground engaging surface.
Patent CA-2427005-A1 (CA)
Inventor: ATLAS DAPHNE
IPC: C07K5/06
Filed: 2001-10-25
Abstract: L'invention concerne un composé antioxydant, caractérisé en ce qu'il comprend: (a) un peptide comportant au moins trois restes d'acides aminés dont au moins deux sont des restes cystéine, chaque reste possédant un groupe sulfhydryle pouvant être facilement oxydé, afin d'exercer une action antioxydative, et au moins deux liaisons peptidiques, chacune pouvant être clivée par au moins une peptidase intracellulaire; et (b) une première moitié hydrophobe ou non chargée, attachée à une extrémité terminale amino du peptide par l'intermédiaire d'une première liaison, et une seconde moitié hydrophobe ou non chargée, attachée à une extrémité terminale carboxy du peptide par l'intermédiaire d'une seconde liaison, la première et la seconde moitié, hydrophobes et non chargées, étant choisies de manière à doter le composé antioxydant de propriétés de miscibilité membranaire, afin de permettre au composé antioxydant de traverser des membranes cellulaires. En outre, le clivage d'au moins deux liaisons peptidiques par au moins une peptidase intracellulaire se traduit par la production de plusieurs espèces antioxydantes comprenant chacune des restes cystéines qui possèdent le groupe sulfhydryle pouvant facilement s'oxyder et qui sont également actifs dans l'action antioxydative. Ainsi ce procédé permet d'obtenir plusieurs espèces différentes d'antioxydants qui agissent en synergie dans l'exercice de l'action antioxydative.
Patent CA-2427718-A1 (CA)
Title: Positioning system for racing cars
Inventor: ASAM ROBERT
IPC: G08G1/127
Filed: 2000-10-25
Abstract: A positioning system for racing cars is disclosed, which comprises a vehicle information device mounted in a racing car, with a positioning device for gathering and output of positional data, by means of which the position of the racing car can be fixed and a transmitter for sending the positional data to a control centre. A number of such vehicle information devices, operated in cooperation with a computational device, allow a useful execution of a positioning system, whereby said computational unit calculates the position of each car on the circuit from the transmitted positional data and stored race track data. The position of each of the race cars can be fixed using the virtual map of the race track course, in the form of the race track data and the transmitted positional data, without the need to establish positioning devices at essentially all the points around the race track. A vehicle coming to rest or leaving the race track can also be determined and precisely located without additional requirements.
Patent CA-2429553-A1 (CA)
Title: A method for enhancing post-processing content of beneficial compounds in beverages naturally containing same
Inventor: ZAPP LORETTA M
IPC: A23F5/04
Filed: 2001-11-20
Abstract: Coffee processing methods and ground coffee end products which depends upon one or more processes for enhancing the post-processing polyphenol content of ground coffee beverage substrate. A first method involves the blending of portions of coffee beans which are variously roasted. The second method involves pre-soaking the beverage substrate before roasting and then quenching the substrate after processing with the liquid in which the substrate was first "pre-soaked".
Patent CA-2431090-A1 (CA)
Title: Method of and apparatus for determining the eccentricity of a hollow billet
Inventor: SAUERLAND MARTIN
IPC: G01B21/00
Filed: 2003-06-04
Abstract: The eccentricity of a hollow billet is measured at the outlet of an inclined-roll rolling mill by launching an ultrasonic pulse into the billet from a laser of a measuring device and measuring the transit time of an echo pulse also utilizing a laser and an optical analyzer. The measuring device is moved, during travel of the hollow billet along a path from the rolling mill linearly into the direction of travel or angularly around the hollow billet to eliminate the effect of the internal helical formation of the eccentricity on the measurements. The wall thickness measurements are evaluated by a computer and subjected to Fourier analysis.
Patent CA-2431532-A1 (CA)
Title: Method and apparatus for reducing end-to-end delay when providing internet telephony over a catv cable network
Inventor: LAZARUS DAVID BERYL
IPC: H04L12/64
Filed: 2001-12-13
Abstract: A method and apparatus is provided for use in providing real-time, packet-switched service to an end-user over a cable data network. The method begins by transmitting over the cable data network a scheduled grant to an end-user gateway in accordance with an unsolicited grant service protocol. The grant authorizes the end-user gateway to transmit a data packet to a cable modem termination system (CMTS) located in the cable data network. Next, an adjustment is made to the time at which subsequent grants are transmitted. The adjustment, which is based on a response of the end-user gateway, is performed to reduce delay between a time when a subsequent data packet is generated and receipt of the subsequent grant.
Patent CA-2432369-A1 (CA)
Title: Cyclic derivatives as modulators of chemokine receptor activity
Inventor: CHERNEY ROBERT
IPC: C07C311/16
Filed: 2001-12-20
Abstract: The present application describes modulators of MCP-1 of formula (I) or pharmaceutically acceptable salt forms thereof, useful for the prevention of  rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.</SDOAB >
Patent CA-2432929-A1 (CA)
Title: Antiviral method of use
Inventor: COLACINO JOSEPH MATTHEW
IPC: A61K31/519
Filed: 2002-02-04
Abstract: The present invention provides a method for treating HCMV in a human requiring said treatment, which comprises administering to said human an effective amount of ALIMTA.
Patent CA-2434633-A1 (CA)
Title: Media/screen look-up-table for color consistency
Inventor: SKINNER GARY W
IPC: G06T5/00
Filed: 2003-07-08
Abstract: In an image rendering system, a method of compensating for system performance changes related to image attributes includes rendering a diagnostic image, sensing at least one image quality from the diagnostic image, updating an image attribute compensation tone reproduction curve based on the sensed image quality and rendering an image based on the updated image attribute compensation tone reproduction curve. For example, image attributes include print media type and a halftone screen selection. An image processing system operative to perform the method of compensation includes a set of image attribute compensation tone reproduction curves. Each curve of the set is associated with a particular combination of image attributes. For example, each curve is associated with a particular media type/halftone screen combination.
Patent CA-2435810-A1 (CA)
Inventor: GOLDSMITH MARK A
IPC: C12Q1/68
Filed: 2002-02-04
Abstract: Cell fusion assays for identifying antiviral compounds are provided. In the cell fusion assays of the subject invention, a first cell that stably expresses on its surface an envelope protein of an enveloped virion and a second cell that stably expresses a receptor for the envelope protein on its surface are employed. The first and second cells each contain one component of a two component Tat reporter system that produces a detectable product in th e presence of cell fusion. In practicing the subject screening methods, the first and second cells are first contacted with each other under cell fusion conditions in the presence of a candidate inhibitory agent. Next, the presen ce or absence of the detectable product is detected. Finally, the inhibitory activity of the candidate agent is derived from the presence or absence of t he detectable product. Also provided are high throughput embodiments of the subject methods. In addition to the subject methods, systems and kits for performing the subject methods are provided.
Patent CA-2437075-A1 (CA)
Inventor: HARE BRADLEY A
IPC: A61B17/32
Filed: 2002-02-11
Abstract: A transverse mode ultrasonic probe (6) is provided which creates a cavitation area along its longitudinal length, increasing the working surface of the probe. Accessory sheaths (104, 107, 108, 111, 121) are also provided for use with the probe to enable a user to select from features most suited to an individual medical procedure. The sheaths provide acoustic enhancing and aspiration enhancing properties, and/or can be used as surgical tools or as medical access devices, protecting tissue from physical contact with the probe.
Patent CA-2438776-A1 (CA)
Inventor: CORSON MATHEW SCOTT
IPC: H04L45/28
Filed: 2002-02-19
Abstract: The present invention provides a method of, computer programs for and apparatus adapted to operate a communications network to generate data defining a forwarding tree for the transmission of messages in said network, said method comprising: a) storing data associating each of the nodes of said network with at least one of N levels of a hierarchy, where N is an integer greater than one; b) operating each of the nodes in each of the first to (N-1)th levels to periodically send a join message to one of the nodes in a superior level in said hierarchy; c) in response to the receipt of a join message at a node, storing tree-defining data indicating that the sender of said join message is a member of a group of descendant nodes for which said receiving node is an ancestor node; whereby said tree-defining data so stored defines said forwarding tree.
Patent CA-2439515-A1 (CA)
Title: Auto-generatrice
Inventor: GUERIN ANDRE
IPC: F03G7/10
Filed: 2003-08-28
Abstract: Le speedmaster prend son électricité, d'un inventer qui transforme 24 volts en 220 volts ou d'une prise de courant d'Hydro Québec, et alimente le moteur électrique, qui lui, fait tourner les roues d'élan ainsi le moteur électrique accélère en 30 secondes et atteint 1725 rpm ainsi entraînant la roue 1 à 700 rpm et la roue 2 à 1650 rpm et la génératrice à 3500 rpm. Donc à cette vitesse la génératrice produit 5500 watts. GÉNÉRATRICE PRODUIT 5500 WATTS MOTEUR ÉLECTRIQUE - 2500 WATTS ÉNERGIE PRODUIT = 3000 WATTS Prototype format réel à l'appui. Inventeur André Guérin 1. Énergie électrique démarre le numéro 16 et l'achemine vers le numéro 20. 2. Transforme le courant électrique 1 phase, 3 phase, pour envoyer numéro 5. 3. Numéro 5 le moteur électrique à l'aide d'une courroie entraîne la roue 1. 4. Numéro 1 roue qui est fixée au numéro 4 boîtier, fait tourner la roue numéro 2 à l'aide du numéro 3. 5. Numéro 2 la roue tourne sur elle-même, fixer sur le numéro 3 et entraîne numéro 4. 6. Numéro 7 poulie d'entrain fait tourner numéro 10. 7. Numéro 10 courroie d'entrain fixer au numéro 7 et 9. 8. Numéro 9 poulie de la génératrice fixer sur l'arbre de la génératrice. 9. Numéro 8 la génératrice fixée sur le boîtier de roulement numéro 19. 10. Numéro 19 boîtierde roulement est fixer à la plaque de la génératrice numéro 25.
Patent CA-2441358-A1 (CA)
Title: Vehicle ramp and hitch tie-down structure
Inventor: TREMBLAY DANIEL
IPC: B60P1/43
Filed: 2003-09-17
Abstract: A crossbar is affixed to an anchor member having a draw bar pointing forward for engagement into a hitch socket of a pickup truck. The crossbar has a pivot bracket affixed to the mid-point thereof, and a pair of hinge pins affixed to both ends thereof. A pair of spaced-apart ramp members are affixed to the hinge pins for angular movement thereof perpendicular to the crossbar. A mast is also movably affixed to the pivot bracket for angular movement thereof perpendicular to the crossbar between the ramp members, between a vertical position and a position below the ramp members in the deployed mode. A hitch arm extends from the mast and has a hitch clamp thereon for engagement with a hitch ball on a transportable vehicle, for retaining the transportable vehicle to the mast, to the draw bar and to the hitch socket of a pickup truck.
Patent CA-2442807-A1 (CA)
Title: Monitoring system and process for the food service industry
Inventor: JACOBSON RONALD
IPC: G06Q30/02
Filed: 2002-04-02
Abstract: A system and process for monitoring at least one but preferably a plurality of service outlets (12) of the type commonly existing in the food service industry, comprising utilization of a portable processor assembly (16) at a local site, which incorporates both manual and automatic input facilities, at least one of which is defined by a temperature acquisition module (30) interfaced for direct communication with the processor assembly. A monitoring program is operable by the processor and comprises a task application defining a plurality of user interactive test items requiring the entry of user responses upon their performance of the test items. The test items are determinative of currently existing conditions of a plurality of operational categories which are established based on the required functions of the one or more sites being monitored.
Patent CA-2443128-A1 (CA)
Inventor: MARTIN DEBRA A
IPC: A61K47/12
Filed: 2002-04-01
Abstract: A transdermal delivery device comprising a multi-phase matrix which includes a solid liquid-retaining member and associated therewith pergolide in liquid form, for example, a transdermal delivery device comprising a barrier layer affixed to one face of the matrix and having an exposed face, the exposed face having affixed thereto a mounting layer, and the other face of the matrix having affixed thereto a removable layer, an example of the liquid-retaining member being an absorbent material, for example, a natural or synthetic fiber gauze, a non-woven medical basorbent, a natural sponge, and a synthetic sponge.
Patent CA-2445030-A1 (CA)
Title: Device for controlling gemstone polishing assembly movement
Inventor: BOTHA MICHIEL J
IPC: B24B9/16
Filed: 2003-10-14
Abstract: The present invention pertains to a device for controlling polishing assembly movement. The device comprises a vertical rod, a motive power means for lowering and lifting, and rotating, oscillating, or both rotating and oscillating the vertical rod about an axis of rotation coaxial with the vertical rod. The device also comprises a pin that is offset from the axis of rotation and connected to the vertical rod for mounting the polishing assembly. Optionally, the device may comprise a sensor for activating movement of the vertical rod.
Patent CA-2445408-A1 (CA)
Title: Quinolone carboxylic acid compositions and related methods of treatment
Inventor: ROY SAMIR
IPC: A61K9/08
Filed: 2002-04-24
Abstract: The present invention relates to the use of quinolone carboxylic acid formulations in the treatment of ocular and periocular infections. The prese nt invention also relates to sustained release compositions comprising specific quinolone carboxylic acid compounds. The invention also relates to quinolone carboxylic acid compositions and methods of preparing the same.
Patent CA-2446034-A1 (CA)
Title: Method and device for mounting a modular drawer and support inside a cabinet
Inventor: WELCH HERB
IPC: A47B88/04
Filed: 2003-10-22
Abstract: A modular drawer system for mounting a movable drawer within a cabinet having a floor includes a drawer having a bottom and side walls. Rollers are mounted to and extend from the side walls. Two guide rails adapted to receive the rollers to mount and guide movement of the drawer are secured to a base, optionally comprising two or more base components. The guide rails are fixed in a substantially parallel relationship at a fixed spacing substantially equal to the spacing between the rollers. The system includes means for securing the base to the cabinet floor.
Patent CA-2446501-A1 (CA)
Title: Automatic mechanically controlled continuously-variable-ratio drive
Inventor: BORGHI GIANNI
IPC: F16H55/56
Filed: 2003-10-24
Abstract: A continuously-variable-ratio drive, having an input shaft; a flywheel integral with the input shaft; a drive pulley idle with respect to the input shaft and defined by two half-pulleys defining a groove of variable size for a V belt; and a centrifugal control assembly. The control assembly has a centrifugal actuating device which intervenes above a first threshold value of the angular speed of the input shaft to connect the drive pulley angularly to the flywheel by means of a friction clutch; and a speed adjusting device which is active over a second threshold value of the angular speed of the input shaft to adjust the size of the groove of the drive pulley and therefore the work diameter of the belt.
Patent CA-2446586-A1 (CA)
Title: Aromatic sulfone hydroxamates and their use as protease inhibitors
Inventor: MISCHKE DEBORAH A
IPC: C07D407/12
Filed: 2002-05-10
Abstract: This invention is directed to aromatic sulfone hydroxamates (also known as "aromatic sulfone hydroxamic acids") and salts thereof that, inter alia, inhibit matrix metalloproteinase (also known as "matrix metalloprotease" or "MMP") activity and/or aggrecanase activity. This invention also is directed to a prevention or treatment method that comprises administering such a compound or salt in an MMP-inhibiting and/or aggrecanase-inhibiting effective amount to an animal, particularly a mammal having (or disposed to having) a pathological condition associated with MMP and/or aggrecanase activity.
Patent CA-2446638-A1 (CA)
Title: Process for preparing carboxylic acids and derivatives thereof
Inventor: TSOBANAKIS PARASKEVAS
IPC: C07C29/147
Filed: 2002-05-07
Abstract: Processes for preparing carboxylic acids and derivatives thereof in which an ammonium salt of the carboxylic acid is heated in the presence of an organic reagent to split the salt and form the acid or, where the organic reagent is an esterifying agent, the corresponding ester. Both the acid and the ester m ay be dehydrated to form unsaturated counterparts.