baber/WOPTO huggingface dataset:
Patent JP-3030385-B2 (JP)
IPC: B41F30/00
Filed: 1991-05-30
Granted: 2000-04-10
Abstract: A coating apparatus is provided with a front roller and a rear roller which rotate in the same rotational sense and opposite to direction of rotation of a parallel cylinder to be coated with fluid material which hardens to a resilient coating thereon. A reservoir of fluid material is provided above a nip between the front and rear rollers, so that the front roller carries a layer of fluid material on a surface thereof to a nip formed between the front roller and the cylinder to be coated, thereby continuously building up thickness of the coating upon the cylinder. Heating elements and temperature sensors in a hood around the cylinder maintain an optimum coating temperature.
Patent JP-4368422-B2 (JP)
IPC: C08F112/08
Filed: 1997-08-22
Granted: 2009-11-18
Abstract: A bis (monoperoxycarbonate) of structure A: <CHEM> where n is 2; R<1> is selected from 1,1,4-trimethyl-4-(t-butylperoxy)pentyl radical and 1,1,4-trimethyl-4-(t-amylperoxy)pentyl radical, and R is a diradical selected from alkylene of 2 to 12 carbon atoms; alkenylene of 4 to 8 carbon atoms, and diradical structures (n) and (o): <CHEM> <CHEM> where R<9> is alkylene diradical of 2 to 8 carbon atoms, x and y are integers from 0 to 5, r and s are integers from 0 to 6, such that a diol corresponding to the diradical R has a molecular weight less than 1000.
Patent JP-4025363-B2 (JP)
IPC: A61K47/42
Filed: 1993-01-08
Granted: 2007-12-19
Abstract: A method for producing a drug system which is a reversible gelled matrix with entrapped drug. The gel is made by combining a polysaccharide, such as dextran, a polymer of glucose, with a natural macromolecule, such as the lectin, concanavalin A, with binding sites for monomers of the polysaccharide. The drug is released in response to exposure of the matrix to free carbohydrate containing the monomer of the polysaccharide for which the natural macromolecule binds.
Patent JP-3574134-B2 (JP)
IPC: A61K51/00
Filed: 1994-11-30
Granted: 2004-10-06
Abstract: A nucleic acid analogue of the PNA type is provided with a kemptide motif and radio-labelled by phosphorylation at a service residue in said motif to provide a radio-labelled nucleic acid analogue having a specific activity in excess of 1 x 10<5> cpm/ mu g <32>P.
Patent JP-3108433-B2 (JP)
IPC: A61P25/28
Filed: 1991-09-24
Granted: 2000-11-13
Abstract: Compounds of formula (I), in which: R1 represents hydrogen or C1-6 alkyl, R2 represents hydrogen, C1-6 alkyl, C3-6 alkenyl, C3-6 alkynyl or C3-6 cycloalkyl, R3 represents one or more radicals selected from hydrogen, hydroxy, C1-6 alkyl, C1-6 alkoxy, halogen, trifluoromethyl, amino, C1-6 alkylamino or di(C1-6 alkyl)amino, R4 represents one or more radicals selected from hydrogen or C1-6 alkyl, A represents hydrogen, C1-6 alkyl, COC(R5R6)N(R7R8) or COOC1-6 alkyl, R5 represents hydrogen, C1-6 alkyl, hydroxy-C1-2 alkyl, mercaptomethyl, (methylthio)C1-2 alkyl, carboxy-C1-2 alkyl, 2-(C1-3 alkoxy)ethyl, (aminocarbonyl)C1-2 alkyl, amino-C1-4 alkyl, 3-imidazolylmethyl, phenylmethyl or (4-hydroxyphenyl)-methyl, or in addition, R5 together with the adjacent nitrogen may represent a piperidine, pyrrolidine or a 2-pyrrolidinone ring, R6, R7 and R8 independently represent hydrogen or C1-6 alkyl, or in addition, R7 and R8 taken together with the nitrogen to which they are attached may represent a C4-5 N heterocyclic ring, and pharmaceutically acceptable acid addition salts thereof, are useful as pharmaceuticals; in particular they possess N-methyl-(D)-aspartate blocking properties and are useful in the treatment and/or prevention of neurological disorders.
Patent JP-3852945-B2 (JP)
IPC: A61P35/00
Filed: 1994-01-21
Granted: 2006-12-06
Abstract: This invention provides a vaccine for stimulating or enhancing the production of an antibody which recognizes a ganglioside in a subject to which the vaccine is administered. The vaccine is comprised of an amount of ganglioside or oligosaccharide portion thereof conjugated to an immunogenic protein effective to stimulate or enhance antibody production in the subject. The vaccine is further comprised of an adjuvant and a pharmaceutically acceptable vehicle. The invention also provides a method of using the vaccine for treating or preventing cancer wherein gangliosides are on the surface or in the stroma of the cancer cells.This invention provides a vaccine for stimulating or enhancing the production of an antibody which recognizes a ganglioside in a subject to which the vaccine is administered. The vaccine is comprised of an amount of ganglioside or oligosaccharide portion thereof conjugated to an immunogenic protein effective to stimulate or enhance antibody production in the subject. The vaccine is further comprised of an adjuvant and a pharmaceutically acceptable vehicle. The invention also provides a method of using the vaccine for treating or preventing cancer wherein gangliosides are on the surface or in the stroma of the cancer cells.
Patent JP-3716429-B2 (JP)
IPC: G03F7/38
Filed: 1996-11-08
Granted: 2005-11-16
Abstract: A treating liquid for making a waterless planographic printing plate with a photosensitive layer and a silicone rubber layer laminated in this order on a substrate, comprising at least one amine compound with two or more amino groups and one or more hydroxyl groups in one molecule. A treating liquid for making a waterless planographic printing plate excellent in plate surface coatability and developability can be obtained.
Patent JP-4781494-B2 (JP)
IPC: A61L27/00
Filed: 1997-10-16
Granted: 2011-09-28
Abstract: The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrated precursor paste. Hardening of the paste occurs rapidly at body temperature and is accompanied by the conversion of one or more of the reactants to poorly crystalline apatitic calcium phosphate. The hardened cements, fillers, growth matrices, orthopedic and delivery devices of the invention are rapidly resorbable and stimulate hard tissue growth and healing. A composite material is provided including a strongly bioresorbable, poorly crystalline apatitic calcium phosphate composite and a supplementary material. The supplementary material is in intimate contact with the hydroxyapatite material in an amount effective to impart a selected characteristic to the composite. The supplemental material may be biocompatible, bioresorbable or non-resorbable. A method for treating a bone defect also is provided by identifying a bone site suitable for receiving an implant, and introducing a strongly resorbable, poorly crystalline apatitic calcium phosphate at the implant site, whereby bone is formed at the implant site. The implant site may be a variety of sites, such as a tooth socket, non-union bone, bone prosthesis, an osteoporotic bone, an intervertebral space, an alveolar ridge or a bone fracture.
Patent JP-3776452-B2 (JP)
IPC: C07C67/56
Filed: 1995-02-22
Granted: 2006-05-17
Abstract: The process for preparing mevalonolactone compounds is carried out by means of batch system chromatography or a simulated moving bed chromatographic process using columns filled with an optical resolution filler comprising a polysaccharide derivative. The simulated moving bed chromatographic process comprises forming a circulation flow circuit comprising a plurality of columns endlessly connected in series; enforcing a fluid to flow through the circuit in one direction; providing the column series alternately with an inlet port through which the fluid is introduced into the column in the flow direction and with an outlet port, through which the fluid is taken out; intermittently shifting activation of the inlet port and the outlet port in the direction of the fluid flow; introducing a solution containing a racemic mevalonolactone compound and an eluent through an inlet port into the circuit; and simultaneously taking out a solution rich in the weakly adsorbable substance and a solution rich in the strongly adsorbable and desorbed substance through the outlet port.
Patent JP-3930903-B2 (JP)
IPC: C07D239/30
Filed: 1996-01-04
Granted: 2007-06-13
Abstract: PCT No. PCT/GB96/00013 Sec. 371 Date Jul. 17, 1997 Sec. 102(e) Date Jul. 17, 1997 PCT Filed Jan. 4, 1996 PCT Pub. No. WO96/23776 PCT Pub. Date Aug. 8, 1996A process for preparing 4,6-dichloropyrimidine is described, comprising treating 4,6-dihydroxypyrimidine with phosphorus oxychloride in the presence of a saturated hindered amine, the hydrochloride salt of a saturated hindered amine, or an unsaturated 5-membered nitrogen containing ring or a mixture thereof, and, as a first step, directly extracting the 4,6-dichloropyrimidine so formed.
Patent JP-4327247-B2 (JP)
IPC: C22C38/44
Filed: 1996-03-08
Granted: 2009-09-09
Abstract: PCT No. PCT/FR96/00363 Sec. 371 Date Nov. 4, 1997 Sec. 102(e) Date Nov. 4, 1997 PCT Filed Mar. 8, 1996 PCT Pub. No. WO96/28575 PCT Pub. Date Sep. 19, 1996A method for making steel wires, wherein an elongate shaped wire is produced by rolling or drawing steel consisting of 0.05-0.5% C, 0.4-1.5% Mn, 0-2.5% Cr, 0.1-0.6% Si, 0-1% Mo, no more than 0.25% Ni, and no more than 0.02% S and P, and a first heat treatment is performed on the shaped wire, including at least one step of quenching under predetermined conditions to achieve an HRC hardness of at least 32, a predominately martensitic and bainitic steel structure and a small amount of ferrite. A shaped wire and a flexible tube for conveying an H2S-containing effluent are disclosed.
Patent JP-4282763-B2 (JP)
IPC: A23L1/0522
Filed: 1997-03-20
Granted: 2009-06-24
Abstract: Method of enhancing a resident population of microorganism in a selected site of the gastrointestinal tract of an animal, the method comprising providing to the animal a selected modified or unmodified resistant startch or mixtures thereof in combination with one or more probiotic microogranisms such that upon ingestion the starch passes through the gastrointestinal tract substantially unutilized until it reaches the selected site where it is utilised by the resident and/or the probiotic microogranisms thereof causing an increase in number and/or activity of the microogranisms.
Patent AU-2001271549-B2 (AU)
Title: Replication deficient adenoviral tnf vector
Inventor: KOVESDI IMRE
IPC: A61K35/76
Filed: 2001-06-27
Granted: 2005-06-09
Abstract: An adenoviral vector comprising (a) an adenoviral genome deficient in the E4 region of the adenoviral genome, (b) a nucleic acid sequence coding for TNF, and (c) a radiation inducible promoter operably linked to the nucleic acid sequence coding for TNF. This invention also provides an adenoviral vector comprising (a) an adenoviral genome deficient in the E4 region of the adenoviral genome, (b) a nucleic acid sequence coding for TNF, and (c) a spacer element of at least 15 base pairs in the E4 region of the adenoviral genome. A method of producing an adenoviral vector and a method of treating a tumor or cancer in a host comprising administering an anti-cancer or anti-tumor effective amount of the adenoviral vector of the present invention also is provided.
Patent AU-2002226663-B2 (AU)
Title: Cutting insert
Inventor: ULIANITSKY DANIEL
IPC: B23C/
Filed: 2002-01-23
Granted: 2007-03-22
Abstract: A generally square-shaped indexable cutting insert with four cutting edges for mounting in milling cutters for either slotting operations or for left-hand and right-hand face milling of right-angled corners in a metal workpiece. The cutting edge is parallel to the bottom surface and has a primary cutting edge extending between two wipers, each wiper being adjacent a corner edge. A first relief surface adjacent the primary cutting edge has a first relief angle and a second relief adjacent the two wipers has a second relief angle that is greater than the first relief angle. The first relief surface has a width dimension measured perpendicularly to the cutting edge that has a minimum value proximal to the two wipers and a maximum value at a central region of the cutting edge.
Patent AU-2002235883-B2 (AU)
Title: 2-heteroaryl-3,4-dihydro-2H-pyrrole derivatives and the use thereof as pesticides
Inventor: ERDELEN CHRISTOPH
IPC: C07D401/04
Filed: 2002-01-31
Granted: 2008-05-29
Abstract: Novel Delta<SUP>1</SUP>-pyrrolines of the Formula (I) in which R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and Het have the meanings given in the description, a plurality of processes for preparing these compounds and their use for controlling pests, and also novel intermediates and processes for their preparation.
Patent AU-2002239226-B2 (AU)
Title: Sample processing apparatus, methods and systems
Inventor: AYSTA JAMES
IPC: B01L99/00
Filed: 2001-09-18
Granted: 2006-06-22
Abstract: Apparatus, methods, and systems for processing sample materials that may be presented in a standard microtiter plate are disclosed. The present invention provides a bridge between the standard microtiter plate systems, methods, protocols, etc. with their stationary wells and rotating sample processing devices that allow users to obtain the rapid processing advantages of the newer sample processing devices while retaining the benefits of the standard microtiter plate formats.
Patent AU-2002251283-B2 (AU)
Title: Managing text message traffic in mobile telephone networks
Inventor: HARDING ROBERT
IPC: H04W4/14
Filed: 2002-04-15
Granted: 2005-01-13
Abstract: A grooming technique for managing text message traffic in mobile telephone networks, such as SMS text messages, involves directing certain text messages to a first delivery means (30) which attempts text message delivery one or more times to a destination mobile switching centre (22) or to a host (24) without passing through a store and forward function. Other text messages are directed to a second delivery means, involving a short message service centre (14), which provides a store and forward function for repeated attempted delivery of the text messages.
Patent AU-2003224545-B2 (AU)
Title: Thienyl compounds
Inventor: LI YAN
IPC: A61P25/16
Filed: 2003-04-15
Granted: 2009-08-13
Abstract: Compounds of formula I: and pharmaceutically-acceptable salts thereof, wherein Ar and R are as defined in the specification, compositions containing such compounds and the use of such compounds and compositions for use in therapy.
Patent AU-2003241326-B2 (AU)
Title: Tyrosine kinase inhibitors
Inventor: WU ZHICAI
IPC: A61K31/4745
Filed: 2003-04-28
Granted: 2008-05-01
Abstract: The present invention relates to imidazopyridine compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.
Patent AU-2004216618-B2 (AU)
Title: Method and apparatus for packaging a drug-device combination product
Inventor: DESTRADUER ALAN J
IPC: A61J1/00
Filed: 2004-09-29
Granted: 2010-12-02
Abstract: A package for a drug-device combination product includes an outer package (102) including a first gas impermeable sheet (104) and a second gas impermeable sheet (106) hermetically sealed there to on three sides. A gas permeable header (108) is attached to an unsealed side of the first sheet (104) and sealed to the second sheet (106) on two sides. The first and second gas impermeable sheets and the header form an interior and an opening communicating with the interior. A gas permeable inner package (118) is disposed within the outer package (102). A product is sealed (120) within the inner package (118). The inner package (118) is placed within the outer package (102) and a top end (122) of the header (108) is sealed to the second sheet (106). The outer package (102) is then sealed by sealing the first gas impermeable sheet to the second gas impermeable sheet at a seal point (128) below the point where the header (108) attaches to the first sheet (104).
Patent AU-2004295042-B2 (AU)
Title: N-Acyl-N'-benzyl-alkylendiamino derivatives
Inventor: THALER FLORIAN
IPC: C07C233/36
Filed: 2004-11-12
Granted: 2010-03-11
Abstract: This invention is related to compounds and use of N-Acyl-N'-benzylalkylendiamino derivatives of the following general formula I <CHEM> wherein  A is a straight or branched C2-C8 alkyl chain; X is a methylene, oxygen, sulphur or a NR<7> group; R<1>   is a straight or branched C1-C8 alkyl or C3-C8 alkenylene or C3-C8 alkynylene chain, optionally substituted with CF3, phenyl, phenoxy or naphthyl, the aromatic rings optionally substituted by one or more C1-C4 alkyl, halogens, trifluoromethyl, hydroxy or C1-C4 alkoxy groups; R<2>, R<3>   are independently hydrogen, a C1-C3 alkyl chain, halogen, trifluoromethyl, hydroxy or C1-C4 alkoxy groups; R<4>, R<5>   are independently hydrogen or C1-C6 alkyl; R<6>   is a hydrogen or a straight or branched C1-C8 alkyl or linked to R<5> can form a five to seven membered lactam; R<7>   is hydrogen or C1-C6 alkyl;  and the pharmaceutically acceptable salts thereof that are active as sodium and/or calcium channel modulators and therefore useful in preventing, alleviating and curing a wide range of pathologies, including, but not limited to, neurological, psychiatric, cardiovascular, inflammatory, ophthalmic, urologic, metabolic and gastrointestinal diseases, where the above mechanisms have been described as playing a pathological role.
Patent AU-2005243673-B2 (AU)
Title: Control of cooling water system using rate of consumption of fluorescent polymer
Inventor: MORIARTY BARBARA E
IPC: C02F5/10
Filed: 2005-04-25
Granted: 2010-04-22
Abstract: A method to control a cooling water system based on the rate of consumption of fluorescent polymer is described and claimed. The method includes providing a cooling water system and a water treatment product including at least one fluorescent polymer and a fluorescent tracer. Measuring the fluorescence of the fluorescent polymer and calculating its rate of consumption provides a way of determining whether to adjust one or more operating parameters in the cooling water system.
Patent AU-2005261827-B2 (AU)
Title: Finger or toe prosthesis
Inventor: CUBBER JAN DE
IPC: A61F2/42
Filed: 2005-07-11
Granted: 2011-06-02
Abstract: The invention relates to a finger or toe prosthesis having an intracorporal implant and an external modular frame constituting the core of the finger or toe prosthesis with a certain number of modules or components, each with its own function, e.g. a joint, which will be assembled to constitute one modular frame, wherein the external modular frame is displaceable fixed to the intracorporal implant. The invention relates to a fail safety mechanism for a finger or toe prosthesis, too, wherein the external modular frame is coupled to the intracorporal implant by a friction-type blocking, a form fit locking, a spring loaded hinge or a non-linear spring allowing hyper-extension or hyper-flexion, ductile deformation or breaking at a predetermined load. The invention relates to a cosmetic or functional cover of the external modular frame as well, which is attached to the frame and supports the function of the frame.
Patent AU-2005298416-B2 (AU)
Title: Process for the preparation of irbesartan hydrochloride
Inventor: KANKAN RAJENDRA NARAYANRAO
IPC: A61P9/00
Filed: 2005-10-26
Granted: 2012-01-19
Abstract: The present invention is concerned with a process for the preparation of 2n-butyl-4-spirocyclopentane-1-[(2'-(tetrazol-5-yl)biphenyl-4-yl) methyl]-2-imidazolin-5-one hydrochloride, irbesartan hydrochloride, novel hydrated and anhydrous crystalline forms thereof, amorphous irbesartan hydrochloride, formulations containing the same, therapeutic uses thereof and methods of treatment employing the same. The process of the present invention is a one-pot process which comprises reacting intermediate compounds 2n-butyl-1, 3-diazaspiro [4,4] non-1-en-4-one and 5-(4' -bromomethyl-biphenyl-2-yl)-1-trityl-lH-tetrazole.
Patent AU-2005300688-B2 (AU)
Title: Transcriptome microarray technology and methods of using the same
Inventor: HARKIN PAUL
IPC: C12Q1/68
Filed: 2005-11-03
Granted: 2012-02-02
Abstract: Arrays containing a transcriptome of a diseased tissue and methods of using the arrays for diagnosis, prognosis, screening, and identification of disease are provided herein. The transcriptome arrays from diseased tissue are useful for diagnosis of a disease by analysis of the genetic profile of a tissue sample specific to a disease state. The genetic profiles are then correlated with data on the effectiveness of specific therapeutic agents. Correlating expression profiles to the effectiveness of therapeutic agents provides a way to screen and select further patients predicted to respond to those therapeutic agents, thereby minimizing needless exposure to ineffective therapy.
Patent AU-2005336407-B2 (AU)
Title: Abrasive body
Inventor: CATALFAMO PASQUALE
IPC: B24B23/02
Filed: 2005-09-16
Granted: 2012-06-28
Abstract: It is disclosed an abrasive body having a work surface (2) that under operating conditions is designed to face a surface of an article of manufacture to be worked; this surface is provided with abrasive means to enable an abrading or finishing working; also present is a predetermined number of tongues (5) emerging from the central portion (4) of the abrasive body (1) to enable engagement of the latter with a support (6). The abrasive body is made of an elastically deformable material and is not fastened to the lower surface (8) of the support (6). The presence of cuts (9) on the tongues (5) increases gripping of the abrasive body on the support and use of the elastic material gives the abrasive body a longer duration and greater yield and allows better finishing off while reducing clogging problems.
Patent AU-2006203340-B2 (AU)
Title: New crystalline form IV of agomelatine, a process for its preparation and pharmaceutical compositions containing it
Inventor: COQUEREL GERARD
IPC: C07C233/18
Filed: 2006-08-03
Granted: 2012-07-19
Abstract: NEW CRYSTALLINE FORM IV OF AGOMELATINE, A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT Crystalline form IV of the compound of formula (I) : NHCOMe MeO (I) characterised by its powder X-ray diffraction diagram. Medicaments.
Patent AU-2006239961-B2 (AU)
Title: Low temperature barriers for use with in situ processes
Inventor: KIM DONG
IPC: E21B36/00
Filed: 2006-04-21
Granted: 2010-03-18
Abstract: A heating system for a subsurface formation is described. The heating system includes a first heater, a second heater, and a third heater placed in an opening in the subsurface formation. Each heater includes: an electrical conductor; an insulation layer at least partially surrounding the electrical conductor; and an electrically conductive sheath at least partially surrounding the insulation layer. The electrical conductor is electrically coupled to the sheath at a lower end portion of the heater. The lower end portion is the portion of the heater distal from a surface of the opening. The first heater, the second heater, and the third heater are electrically coupled at the lower end portions of the heaters. The first heater, the second heater, and the third heater are configured to be electrically coupled in a three-phase wye configuration.
Patent AU-2006245528-B2 (AU)
Title: Safety line anchor
Inventor: BEALE RICHARD ALAN FREDERICK
IPC: A62B1/04
Filed: 2006-04-25
Granted: 2012-03-22
Abstract: An anchor assembly for an elongate safety linecomprises safety line gripping means connected to a bracket means by a releasable clamping means. The releasable clamping means comprises a tapered clamp formed by first and second opposed clamping surfaces defining a tapered space between them, a tapered member having a tapered profile matching the tapered space and a clamping element adapted to urge the first and second clamping surfaces together to clamp the tapered member between them.