baber/WOPTO huggingface dataset:
Patent DE-69426785-D1 (DE)
Inventor: PRASAD JANNAIH S
IPC: A61B17/06
Filed: 1994-03-30
Granted: 2001-04-05
Abstract: A surgical suturing needle is formed to have a needle shaft (12) with a rectangular cross-section and a needle head (14) with a triangular needle point (18). A transitional portion (21) between the needle shaft (12) and the needle head (14) is formed to have a maximum width (W1) greater than the width (W2) of the needle shaft (12). A plurality of cutting edges (24) extend from the needle point (18) to at least the maximum width section of the transitional portion (21). After forming and grinding the suturing needle, it is immersed in an acid bath and exposed to an electrical field. Finally, the surgical needle is heat-treated to increase its strength and resistance to bending or breaking.
Patent DE-69431483-D1 (DE)
Inventor: GRUBER PATRICK RICHARD
IPC: C08F299/04
Filed: 1994-07-27
Granted: 2002-11-07
Abstract: A copolymerized poly(lactide) polymer. A lactide is copolymerized with an epoxidized fat, oil, or mixture thereof thereby resulting in poly(lactide) copolymers having improved processing properties over prior poly(lactide)s.
Patent DE-69434814-D1 (DE)
Inventor: BRONSTEIN IRENA
IPC: C07F9/12
Filed: 1994-05-06
Granted: 2006-09-14
Abstract: Novel 1,2-dioxetanes with improved chemiluminescent properties, such as signal intensity, S/N ratio, T½, -etc. are provided by spiroadamantyl 1,2-dioxetanes, wherein the remaining carbon atom of the ring bears an alkoxy, aryloxy, or arylalkoxy substituent, and either a phenyl or naphthyl ring, this aromatic ring bearing, at the meta position on the phenyl group, or a nonconjugated position on the naphthyl ring, an OX moiety wherein X is an enzyme-cleavable group, which when removed from the dioxetane, leaves the oxyanion which decomposes with chemiluminescence, the aryl ring further bearing an electron-active substituent Z. The nature and placement of the Z substituent, at a position not adjacent the point of attachment to the dioxetane ring, strongly influences the properties of the dioxetane. Assays, as well as kits for the performance of those assays, include the dioxetane, an enzyme capable of cleaving the X group, and in certain cases, membranes and chemiluminescent enhancement agents.
Patent DE-69505183-D1 (DE)
Inventor: CORTES DAVID ANDRES
IPC: C07C205/00
Filed: 1995-04-25
Granted: 1998-11-12
Abstract: The present invention provides a method for the preparation of a 4-halo-2'-nitrobutyrophenone compound having the structural formula Iwhichcomprises reacting a 2-nitrobenzoyl halide compound having the structural formulawherein X and R are as described above with at least one molar equivalent of the magnesium enolate of acetyl-butyrolactone in the presence of a solvent at an elevated temperature and optionally concentrating the resultant reaction mixture by distillation of the solvent.The formula I compound is an important intermediate in the manufacture of a sulfamoyl urea herbicidal agent.
Patent DE-69507309-D1 (DE)
Inventor: BAECKSTROEM REIJO
IPC: C07C201/16
Filed: 1995-09-20
Granted: 1999-02-25
Abstract: PCT No. PCT/FI95/00513 Sec. 371 Date May 8, 1997 Sec. 102(e) Date May 8, 1997 PCT Filed Sep. 20, 1995 PCT Pub. No. WO96/09274 PCT Pub. Date Mar. 28, 1996The invention provides a method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde by reacting 3-ethoxy-4-hydroxy-5-nitrobenzaldehyde with a reagent comprising zinc chloride, water and hydrogen chloride.
Patent DE-69508266-D1 (DE)
Inventor: HUARD MARCEL
IPC: G07F17/32
Filed: 1995-10-16
Granted: 1999-04-15
Abstract: An auxiliary game provides an auxiliary opportunity for players at a casino to win a prize by participating with a relatively small contribution each time they play a round in the principal casino game. To increase the element of random chance or luck in winning a prize in the game, a method and apparatus is provided for randomly choosing a winning card or combination of cards, or randomly selecting a person or group of persons eligible to win upon possession of the card or combination of cards. The amount of the prize can also be randomly selected either as a fixed amount or percentage of a maximum amount or a progressive jackpot.
Patent DE-69509838-D1 (DE)
Inventor: DOLEANS FRANCIS
IPC: C12M1/26
Filed: 1995-03-10
Granted: 1999-07-01
Abstract: PCT No. PCT/FR95/00285 Sec. 371 Date Nov. 7, 1995 Sec. 102(e) Date Nov. 7, 1995 PCT Filed Mar. 10, 1995 PCT Pub. No. WO95/24463 PCT Pub. Date Sep. 14, 1995An applicator device for a flat element (1) for sampling of microorganisms has a flat recess (3) for containing and retaining a culture medium (4), and with at least one border (5) arranged to the outside of the recess, wherein the applicator device has a plate (6), a base (7) for holding the plate at a distance from the surface (2) from which the sample is to be taken, defining a support surface (9), and forming an opening (7a) for engaging the sampling element (1) parallel with respect to the support surface (9), and with the free surface (4a) of the culture medium directed downwards, a pusher (10) mounted so as to be free in terms of translation on the plate (6) perpendicular to the support surface (9), with a bearing head (11) which protrudes from the inside of the base (7), a device (12) for returning the pusher towards the support surface (9) and at least one shoulder (13) defining a bearing surface (14) for retaining the border (5) of the sampling element (1).
Patent DE-69516856-D1 (DE)
Inventor: KOVAROVIC JOSEF
IPC: B21D19/08
Filed: 1995-02-13
Granted: 2000-06-15
Abstract: PCT No. PCT/GB95/00288 Sec. 371 Date Oct. 7, 1996 Sec. 102(e) Date Oct. 7, 1996 PCT Filed Feb. 13, 1995 PCT Pub. No. WO95/21710 PCT Pub. Date Aug. 17, 1995A hemming machine adapted to externally and internally hem a sheet metal fabrication comprising an anvil which itself is apertured so as to register with an aperture in the metal fabrication which is to be internally hemmed, wherein additional hemming apparatus is provided mounted at the upper end of a drive, and support means is located below and protruding up through the opening in the anvil so as to protrude the opening in the fabrication, further comprising a hemming tool displaceable vertically and horizontally having a chamfered lower leading edge, a slidable block carrying the tool at one end, drive means for positioning the slide vertically, and further drive means for positioning the block within the slide for positioning the tool horizontally, a second anvil resiliently displaceable and engaging the underside of the tool or normally raise the latter relative to its lowermost position, and wherein the upper surface of the block is adapted to withstand an impact force and transmit same to the tool to force the tool in a downward direction until the tool and block bottom on stop means. A method of internal and external hemming is also disclosed.
Patent DE-69531895-D1 (DE)
Inventor: IMEOKPARIA DANIEL D
IPC: C08J9/12
Filed: 1995-01-11
Granted: 2003-11-13
Abstract: Disclosed is an extruded, open-cell alkenyl aromatic polymer foam useful in insulating applications. The foam has an open cell content of about 30 to about 80 percent. The foam further has in minor dimension and cross-section of greater than 0.25 inches. The foam has a high heat distortion temperature, and is particularly useful in roofing applications. Further disclosed is a process for making the open-cell foam.
Patent DE-69532127-D1 (DE)
Inventor: BRENT ROGER
IPC: C12Q1/6897
Filed: 1995-07-20
Granted: 2003-12-18
Abstract: Determining whether a 1st protein (A) is capable of physically interacting with a 2nd protein (B) comprises providing a host cell which contains: (i) a reporter gene operably linked to a DNA-binding-protein recognition site; (ii) a 1st fusion gene which expresses (A), comprising a 1st protein covalently bonded to a binding moiety which is capable of specifically binding to the DNA-binding-protein recognition site; and (iii) a 2nd fusion gene which expresses (B), comprising a 2nd protein covalently bonded to a gene activating moiety and being conformationally-constrained, and measuring expression of the reporter gene as a measure of an interaction between (A) and (B). The same system is applied in: (i) detecting an interacting protein in a population of proteins; (ii) identifying a candidate interactor; and (iii) assaying an interaction between (A) and (B).
Patent DE-69535091-D1 (DE)
Title: Humane prostacyclinsynthase
Inventor: TANABE TADASHI
IPC: C12N15/61
Filed: 1995-04-27
Granted: 2006-08-10
Abstract: A DNA comprising a DNA having a nucleotide sequence encoding the amino acid sequence of human-originated prostacyclin synthase (PGIS) substantially depicted in Sequence No. 12, a vector comprising said DNA, a host cell transformed with said vector and a method for preparing human-originated PGIS comprising culturing said host cell in a medium. A polypeptide having the amino acid sequence of human-originated PGIS substantially depicted in Sequence No. 12 and an antibody having a reactivity with said human-originated PGIS. A pharmaceutical composition comprising said DNA or a vector comprising said DNA. A method for promoting the production of PGI2 and a method for treating the diseases induced by a low production of PGI2, comprising introducing said DNA or a vector comprising said DNA into human or other animals. The present invention clarifies the primary structure of human-originated PGIS and the nucleotide sequence encoding same. The PGIS and its DNA are useful as reagents for the development of therapeutic agents for the cardiovascular diseases induced by the production imbalance between PGI2 and TXA2, and as diagnostics for determining the in vivo tissue expression level and distribution of PGIS or mRNA thereof. Moreover, they can be used as therapeutic agents for cardiovascular diseases, which introduce PGIS and the like into human or other animals in a lesion-specific manner. The production method of the present invention is useful for the easy and efficient mass production of the human-originated PGIS. The antibody of the present invention is useful for the purification of the human-originated PGIS and immunohistochemical analysis of the cause of a disease.
Patent DE-69603207-D1 (DE)
Inventor: BRITTON CHARLES JONATHAN
IPC: B29C57/00
Filed: 1996-11-29
Granted: 1999-08-12
Abstract: A container is made in two stages from material such as thermoplastics that is deformable when heated. In the first stage a preform (1) is injection moulded, the mould parts easily releasing a tubular body (2) with a closed end and an outwardly projecting rim (3) at the open end. On or in the surface of the rim facing away from the body there is a formation such as a spiral rib (5) or groove. In the second stage the still heated preform (1) is blow moulded, possibly with some preliminary mechanical stretching, with the blow pin (9) seated in the open end of the body (2) and the preform held by the outer part (7) of its rim. The wall of the body (2) is expanded and the inner part (4) of the rim is urged away from the blow pin (9), deforming into a short tubular mouth with the formation (5) facing inwards. A spiral becomes a screw thread for receiving a screw-in cover.
Patent DE-69604352-D1 (DE)
Inventor: BOUCHER JEAN
IPC: H02G9/06
Filed: 1996-07-25
Granted: 1999-10-28
Abstract: The material constitutes a blanket of nonwoven 50 mm long natural or synthetic fibres, e.g. polypropylene fibres, with a diameter about 170-180 mu m and specific weight 30 g/km. The blanket weighs 1 kg/m<2> and is 12 mm thick under a pressure of 2 kPa. The retaining sheet (3) is woven from small strips of polypropylene. It weighs 100 g/m<2> and is bonded adhesively to the blanket, overlapping each edge and folded back over the upper surface. The composite product is loaded on a vibration table with silica sand of grain size 50-200 mu m to a density of about 15 kg/m<2>. It is supplied as a strip of constant width of about 350 mm.
Patent DE-69611163-D1 (DE)
Inventor: DIACHUK WOLODYMYR
IPC: B01D50/00
Filed: 1996-03-22
Granted: 2001-01-11
Abstract: A modular air-cleaning apparatus for the treatment of contaminated air. The apparatus includes a plurality of modular units cooperatively interconnected, wherein the plurality of units includes at least one separator unit functioning on non-collisional principles and at least one filtration unit functioning on collisional principles. Each modular unit is constructed of a durable and machinable material that is capable of withstanding harsh environmental conditions of use and is formed in a rectangular shape around four corner posts. Each post possesses at least one exposed, outwardly-facing surface with a side margin parallel to a long dimension of the post. The posts aid both in establishing and maintaining a mechanical connection between the unit and another of the modular units with which it is in operable connection, and in enhancing structural and mechanical characteristics of the unit. The posts have a plurality of surface faces, wherein one or more of the faces is adapted for operative connection to another one of the modular units.
Patent DE-69614955-D1 (DE)
Inventor: GUERARD BRUNO
IPC: G01T1/164
Filed: 1996-06-27
Granted: 2001-10-11
Abstract: A method in nuclear medicine of obtaining a truncation-corrected image of a patient's body, according to which the patient's body is placed on a bed of a nuclear medicine machine including at least one detector head equipped with a detection surface of nuclear rays; a first truncated image in projection of the patient's body is acquired; a second image in projection of the patient's body at an angular position of the first truncated image in projection is acquired. An item of information from the second image is introduced in the first image (P1) with a view to correcting it in its truncated part. The invention applies, in particular, to tomographic examinations.
Patent DE-69617051-D1 (DE)
Inventor: SCHULTHESS ADRIAN
IPC: B29C67/00
Filed: 1996-12-10
Granted: 2001-12-20
Abstract: PCT No. PCT/EP96/05508 Sec. 371 Date Jun. 18, 1998 Sec. 102(e) Date Jun. 18, 1998 PCT Filed Dec. 10, 1996 PCT Pub. No. WO97/23342 PCT Pub. Date Jul. 3, 1997The present invention relates to a process for the stereolithographic preparation of a three-dimensional object, wherein the object is built in a container which contains a radiation-curable liquid formulation with fillers by a repeated alternating succession of process steps (a) and (b). In step (a), a layer of the radiation-curable liquid formulation, one limitation of which is the surface of the formulation, is cured using suitable radiation within an surface area which corresponds to the desired cross-section of the three-dimensional object to be formed at the level of this layer. In step (b), said cured layer is coated with a new layer of the radiation-curable liquid formulation. The process comprises homogenizing the radiation-curable liquid formulation continuously or discontinuously to such an extent that there is no noticeable change in the filler content of the radiation-curable liquid formulation in the area of that layer with which the cured layer is coated in step (b). This process enables the skilled person to choose fillers solely according to the purpose envisaged therefor without encountering technical problems or problems relating to the quality of the stereolithographically produced object resulting from sedimentation of the fillers during preparation of the object.
Patent DE-69626095-D1 (DE)
Inventor: BORZATTA VALERIO
IPC: C07D401/14
Filed: 1996-11-26
Granted: 2003-03-13
Abstract: Compounds of the formula (I)in which the polydispersity {overscore (M)}w/{overscore (M)}n is 1; n is 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14 or 15; the radicals R1 are for example hydrogen or C1-C8alkyl; R2 is for example C2-C12alkylene; the radicals A are independently of one another -OR3, -N(R4)(R5) or a group of theR3, R4 and R5, which are identical or different, are for example hydrogen or C1-C18alkyl, or -N(R4)(R5) is additionally a group of the formulawith Y being -O-, -CH2-, -CH2CH2- or >N-CH3; X is -O- or >N-R6; R6 is for example hydrogen or C1-C18alkyl; R is preferably a group of the formulaand the radicals B have independently of one another one of the definitions given for A; with the proviso that in the individual recurrent units of the formula (I), each of the radicals B, R, R1 and R2 has the same or a different meaning, are useful as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials, in particular synthetic polymers.
Patent DE-69629576-D1 (DE)
Inventor: MORSEY A
IPC: C12R1/19
Filed: 1996-10-17
Granted: 2003-09-25
Abstract: The invention relates to a culture system for stable and high-level production of DNA contained on recombinant plasmids, and to the bacteria and plasmids which comprise the culture system. The bacterial cell chromosome is irreversibly altered, in one embodiment, so as to produce a substance toxic to the bacterium; in a second embodiment so as to render the cells unable to synthesize and assimilate an essential metabolite, and, in a third embodiment, to be incapable of producing a required intracellular protein that does not lead to a secreted product. In every case, the recombinant plasmid includes genetic material which functionally complements the chromosomal alteration. If the DNA on the plasmid is to be used in therapeutic applications or for administration to eukaryotes, the genetic material will have no functional or structural equivalent in eukaryotic cells, and will not result in production of mRNA or a polypeptide that acts on any eukaryotic cell component. Any peptide produced is, desirably, not toxic to the bacterial cells.
Patent DE-69630303-D1 (DE)
Title: Rotor
Inventor: HARMAN JAYDEN DAVID
IPC: F03B3/12
Filed: 1996-07-08
Granted: 2003-11-13
Abstract: PCT No. PCT/AU96/00427 Sec. 371 Date Feb. 17, 1998 Sec. 102(e) Date Feb. 17, 1998 PCT Filed Jul. 8, 1996 PCT Pub. No. WO97/03291 PCT Pub. Date Jan. 30, 1997A rotor (18) for use with a fluid flow generator or reactor, the rotor being intended to rotate about a central axis (19) and having a surface which defines an arcuate fluid pathway for fluid flow about the central axis about which the rotor is able to rotate, wherein the surface has the configuration of a logarithmic curve substantially conforming to the mathematical progression known as the Golden Section or the Fibonacci Progression.
Patent DE-69635565-D1 (DE)
Inventor: FERRARA NAPOLEONE
IPC: C07K16/22
Filed: 1996-03-28
Granted: 2006-01-12
Abstract: The present invention provides human vascular endothelial cell growth factor (hVEGF) antagonists, including monoclonal antibodies, hVEGF receptors, and hVEGF variants that are useful for the treatment of age-related macular degeneration, as well as other diseases and disorders characterized by undesirable or excessive neovascularization.
Patent DE-69703381-D1 (DE)
Inventor: GUNTER IAN ALAN
IPC: C12M1/00
Filed: 1997-01-23
Granted: 2000-11-30
Abstract: A method and apparatus for heating specimens in wells of a metallic specimen carrier. The specimen carrier is heated by applying resistive heating directly to the carrier. An AC source and transformer may be used where the specimen carrier is in series with a single turn secondary winding of the transformer.
Patent DE-69707103-D1 (DE)
Inventor: LIN F
IPC: A23K1/16
Filed: 1997-01-27
Granted: 2001-11-08
Abstract: A food composition having improved palatability to cats comprising a nutritious food mass and an palatability enhancing amount of a choline compound. The choline compound is incorporated within, or applied to the surface of, the cat food composition.
Patent DE-69708331-D1 (DE)
Inventor: WEINBERG HENRY W
IPC: B01J19/00
Filed: 1997-07-22
Granted: 2001-12-20
Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.
Patent DE-69717117-D1 (DE)
Inventor: STOLOWITZ MARK L
IPC: C07D207/46
Filed: 1997-07-24
Granted: 2002-12-19
Abstract: Boron compound complexing reagents and methods of synthesizing these reagents are disclosed. These reagents, including those shown as General Formula (I) and General Formula (II) may be used, after further reactions described herein, to complex with boronic compounds, such as phenylboronic acid or derivatives thereof. Boron compound complexing reagents, boron compound complexes, and methods of synthesizing these reagents and complexes are disclosed. These reagents and complexes include those shown in General Formula (III), General Formula (IV), and General Formula (VI). In one embodiment, the reagents of General Formula (III) may be used to produce, after condensation with a bioactive species (BAS), the reagent of General Formula (IV). The reagent of General Formula (IV) may be used to form a complex with a boron compound, such as a complex shown in General Formula (VI).
Patent DE-69726633-D1 (DE)
Inventor: FUCHS KENNETH
IPC: G06F17/24
Filed: 1997-02-20
Granted: 2004-01-22
Abstract: A method and apparatus for displaying physiological signals acquired from a patient in a manner that allows for reliably associating with the physiological signals (40-46) acquired from the patient user generated message information (48-54). The method comprises the steps of, receiving at a central station (28) physiological signals acquired from a patient; and arranging a display portion of the central station to have at least one first display area (40-46) dedicated for displaying said physiological signals, and at least one second display area (48-54), located adjacent said first display area, dedicated for displaying a user generated message related to the physiological signals displayed in said first area. <IMAGE>
Patent DE-69728761-D1 (DE)
Inventor: ADACHI HIROYUKI
IPC: C07D401/10
Filed: 1997-02-10
Granted: 2004-05-27
Abstract: Compounds represented by general formula ÄIÜ <CHEM> or salts thereof, wherein R<1> represents C1-6 alkyl; R<2> represents halogeno, C1-6 alkylsulfonyl, etc.; R<3> and R<4> each represents C1-6 alkyl or C1-6 haloalkyl; and R represents hydrogen or C1-6 alkyl. Compositions containing the compounds represented by formula ÄIÜ are useful as herbicides having selectivity corn and wheat.
Patent DE-69731095-D1 (DE)
Inventor: COPPENS THEO
IPC: A23L7/20
Filed: 1997-07-23
Granted: 2004-11-11
Abstract: Process for the preparation of malted cereals, wherein the steeping step includes one or more wetting stages at a temperature between 5 and 30° C. preferably between 10 and 20° C., until the material has a moisture content between 20 and 60% by weight, preferably between 38 and 47%, wherein after a germination period between 2 and 7 days, preferably between 3 to 6 days at a temperature between 10 and 30° C., preferably between 14 and 18° C., the steeped and germinated cereals are preferably kilned by increasing the temperature to values between 40 and 150° C. until the material has a moisture content between 2 and 15% by weight, and wherein one or more microbial cultures selected from the group consisting of one or more bacteria and/or one of more activated spores are added in one or more times during the process.
Patent DE-69733493-D1 (DE)
Inventor: VAN GORP L
IPC: A61P29/00
Filed: 1997-07-03
Granted: 2005-07-14
Abstract: A method of inhibiting thrombin generation and of inhibiting complement activation by using a dermatan sulfate having at least 2 sulfate groups per disaccharide obtained by chemical sulfation of native dermatan sulfate. The resulting dermatan sulfate having an average molecular weight from about 5000 to 35000 Daltons is characterized by (i) a high content of L-iduronic->4,6-di-O-sulfated N-acetyl-D-galactosamine residues, and (ii) a specific heparin cofactor II-mediated anti-thrombin activity, depending on average molecular weight, between about 25 to 125 U/mg.