baber/WOPTO huggingface dataset:
Patent CA-2561187-A1 (CA)
Inventor: PHILHOWER SCOTT
IPC: A61M39/10
Filed: 2005-03-24
Abstract: A method and apparatus for an improved luer fitting connector is disclosed.  The luer fitting connector includes a male or female luer fitting member and a locking member. The locking member may have at least one of a skeletal handle, a finlike handle, a cavity grip, and an undulating grip. The luer fitting connector also may include a male or female luer fitting member having a conical restraining surface and a locking member having a plateau shaped protrusion. A method of assembly of luer fitting connector members is also disclosed. The method may include providing a male or female luer fitting member having a conical restraining surface and providing a locking member having a plateau shaped protrusion. The method also may include mounting the locking member upon the male or female luer fitting member from the rear.
Patent CA-2564010-A1 (CA)
Inventor: DRUESNE GUY
IPC: B21D26/049
Filed: 2005-04-13
Abstract: Said method wherein a) said container (1, 6) is placed in a two halves mould (2) having an internal shaped wall (21), an b) an internal pressure P of a fluid is build up so as to shape said skirt (12), is characterized in that an external pressure P' of a fluid is applied in a said upper space (101) contiguous to an external or upper surface (100) of said open top end (10) and/or in a said lower space (141) contiguous to an external or lower surface (140) of said shaped bottom end (14), so as to have, during said span of time At, a pressure difference  DELTA P = ¾P-P'¾ low enough to prevent any distortion of said shaped open top end (10) and/or said shaped bottom end (14), so as to form a shaped metallic container (1', 6'). <IMAGE>
Patent CA-2564513-A1 (CA)
Title: I-dmoi derivatives with enhanced activity at 37·c and use thereof
Inventor: LACROIX EMMANUEL
IPC: C12N15/55
Filed: 2005-04-27
Abstract: I-DmoI derivatives with enhanced cleavage activity at 37~C, said mutant comprising a sequence of a mutant of a I-DmoI endonuclease or a chimeric 5 derivative thereof including at least the first I-DmoIdomain, said sequence comprising the substitution of at least : (i) one of the residues in positions 4, 20, 49, 52, 92, 94 and/or 95 of said first I-DmoIdomain, and/or (ii) one of the residues in positions 101, 102, and/or 109 of the linker or the beginning of the second domain of I-DmoI, if present. 10 Polynucleotide encoding said derivatives, cell, animal or plant comprising said polynucleotide and use thereof for isolating meganucleases with new DNA target specificity.
Patent CA-2566213-A1 (CA)
Title: 2-{[2-(2-methylamino-pyrimidine-4-yl)-1h-indole-5-carbonyle]-amine}-3-(phenylpyridine-2-yl-amine)-acide propionique substantiellement pur comme inhibiteur de kinase ikb
Inventor: HADDAD EL-BDAOUI
IPC: A61K31/506
Filed: 2005-05-11
Abstract: La présente invention est destinée au composé substantiellement pur de formule (A) ou à un sel pharmaceutiquement acceptable ou un solvat dudit composé ; à une composition pharmaceutique comprenant la quantité pharmaceutiquement efficace du composé de formule (A) et un vecteur pharmaceutiquement acceptable ; l'utilisation d'un composé de formule (A) ayant une activité d'inhibiteur, de préférence un inhibiteur sélectif, de IkB (IKK), en particulier IKK-2 et les méthodes liées à cela.
Patent CA-2566809-A1 (CA)
Title: Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
Inventor: CHEN DAWEI
IPC: C07D241/44
Filed: 2005-05-17
Abstract: The invention provides certain acylthiourea derivatives and pharmaceutically acceptable salts thereof. These compounds possess potent antiviral activity.  The invention particularly provides compounds that are potent and/or selective inhibitors of hepatitis C virus replication. The invention also provides pharmaceutical compositions containing a compound of the invention and at least one pharmaceutically acceptable excipient and packaged pharmaceutical compositions comprising such a pharmaceutical composition in a container together with instructions for using the composition to treat a viral infection. The invention further comprises a method of inhibiting hepatitis C  virus replication by contacting a compound of the invention with a cell that is infected by hepatitis C virus and a method of treating or preventing hepatitis C viral infection by administering an amount of a compound of the invention to a subject in need thereof.
Patent CA-2566830-A1 (CA)
Title: Method and apparatus for converting objects between weakly and strongly typed programming frameworks
Inventor: BELL LLOYD CLAYTON DWAYNE
IPC: G06F9/45
Filed: 2004-02-04
Abstract: A mapping method for converting objects in order to optimize utilization of a programming environment on an associated platform includes the steps of identifying a strongly typed object and a type of conversion. A name of a weakly typed object is based upon an attribute associated with a target object and reflection is used on the strongly typed object to obtain properties of the object-input parameter. Default names are assigned and stored based upon the obtained properties in a dictionary cache. The dictionary cache is used to complete attributes associated with new object for use in the programming environment.
Patent CA-2567551-A1 (CA)
Title: Fibre optic sensor method and apparatus
Inventor: PAULSON PETER O
IPC: G01P13/00
Filed: 2005-05-24
Abstract: This invention uses an interferometric fibre optic sensor, particularly a Sagnac or Michelson interferometer, in a first fibre to monitor a sensing length of the first fibre and to detect disturbances. Signals indicating disturbances are classified as being of interest or not of interest, depending on predetermined criteria. Disturbances of interest can be, for example, the breaking of reinforcement wires in concrete pipe, the breaking of wires in suspension cables, a fire, a pipeline leak, or an intrusion. A location sensor system is used to determine the location of disturbances of interest, and to confirm the interferometer signal to reduce noise. The location sensor system is a fibre optic sensor, such as a phase OTDR sensor or a Brillouin effect sensor, which can detect the location of events it senses. It is present either in the first fibre or in a separate fibre laid adjacent the first fibre along its sensing length, as for example in the same optical cable.
Patent CA-2567851-A1 (CA)
Inventor: ZHOU CHANGYOU
IPC: C07D235/04
Filed: 2005-05-20
Abstract: Compounds of the formulae (I) and (II): (wherein Q, X, E, G1, G2, R2, R3, R4, R5, R6 and Z are as defined herein) which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.
Patent CA-2569182-A1 (CA)
Inventor: WIDMER NEIL COLIN
IPC: F23N5/24
Filed: 2006-11-29
Abstract: A system, a method, and an article of manufacture for adjusting temperature levels in predetermined locations in a boiler system (12) are provided. The boiler system (12) has a plurality of burners and a plurality of temperature sensors (110, 112, 114, 115) and CO sensors (94, 96, 98, 99) disposed therein. The system determines locations within the boiler system (12) that have relatively high temperature levels utilizing the plurality of temperature sensors (110, 112, 114, 115) and then adjusts A/F  ratios of burners affecting those locations to decrease the temperature levels at the locations while maintaining CO levels at or below a threshold level.
Patent CA-2570408-A1 (CA)
Inventor: EVANS ANN
IPC: C23G1/02
Filed: 2006-12-06
Abstract: A method of removing an oxide layer from a surface of a metallic component (10), includes: contacting the surface with an alkaline cleaner, followed by contacting the surface with an acidic solution. The method is especially useful for removing oxide layers from the interior of hollow gas turbine engine components. The cleaned surface may be provided with an oxide-resistant coating by a pack aluminide coating process.
Patent CA-2571548-A1 (CA)
Inventor: ERIKSSON JAN
IPC: E21B33/128
Filed: 2005-07-07
Abstract: The present invention relates to an arrangement for affixing an expandable packer 22, 32 in a hole 30, wherein the arrangement includes a piston-and-cylinder device 11,12 with which the piston can be caused to move in the cylinder with the aid of a pressurized medium. Expansion of the packer is effected with the aid of the movement of the piston 11, by transferring the force generated by piston movement to an expandable part 24, 34 of the packer 22, 32 so that said part will expand. Expansion of the packer results in the packer being firmly affixed in the hole by means of friction. The arrangement also includes an elongate main body 1 that has a through-penetrating aperture extending in the longitudinal direction of the body. The main body 1 has a front end 3, which faces inwardly of the hole when fastening the packer and towards the packer. The body includes a rear end 4 which carries means 9 for connection to a filler supply means, wherewith filler is delivered to the hole via the through-penetrating aperture 2 and via the packer 22, 32 subsequent to having affixed the packer in the hole. At least a part of the main body 1 is formed as a piston rod 16 on which and along which the piston 11 can move. The arrangement also includes pressure connection means 10 for connection to said pressurized medium, and a connection 19 between said pressure connection means and the piston 11.
Patent CA-2573373-A1 (CA)
Title: Method for producing tiotropium salts and silicon derivatives as intermediates
Inventor: BELZER WERNER
IPC: C07D451/10
Filed: 2005-08-23
Abstract: The invention relates to a novel method for producing tiotropium salts of general formula (1) via the corresponding silyl compound, wherein X- can have the meanings cited in the claims and in the description.
Patent CA-2576168-A1 (CA)
Inventor: FRALEY MARK E
IPC: A61K31/42
Filed: 2005-08-15
Abstract: The present invention relates to dihydroisoxazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Patent CA-2578409-A1 (CA)
Title: A method for preparing irbesartan and intermediates thereof
Inventor: ZHU JINGYANG
IPC: C07D487/10
Filed: 2005-08-23
Abstract: A method for preparing irbesartan and intermediates thereof. Irbesartan has the structure of Formula (I).
Patent CA-2587572-A1 (CA)
Title: Dap-10 and uses thereof
Inventor: HYKA NEVILA
IPC: A61P37/04
Filed: 2005-11-22
Abstract: The present invention relates to methods for identifying and using modulators of DAP10 biological activity in vivo that are useful in the treatment of cancer and autoimmunity.
Patent CA-2592261-A1 (CA)
Title: Fgf18 production in prokaryotic hosts
Inventor: LIU HONG Y
IPC: C07K14/50
Filed: 2005-12-12
Abstract: The expression vectors and methods using an E. coli expression system for the large scale production of FGF18 are described. The vectors utilize the FGF18 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Using the expression vectors, the FGF18 gene was produced in E. coli to a level of greater than 1 g/L in fed batch fermentation. Also included are OmpT deficient E. coli strains, as well as OmpT and fhuA negative strains transformed with an FGF18 expression vector.
Patent CA-2593780-A1 (CA)
Inventor: KANDEFER-SZERSZEN MARTYNA
IPC: A61K31/194
Filed: 2006-01-10
Abstract: The invention dissolves the problem of antineoplastic preparation. The essence of the solution is that the preparation contains alpha-ketoglutarate (AKG) or/and glutamine or/and glutamate or/and alpha-ketoglutarate of ornithine or/and dipeptides of glutamine and other amino acids or/and tripeptides of glutamine and other amino acids or/and di- and tripeptides of glutamate with other amino acid, or/and mono- and divalent metal salts and other of alpha-keto-glutarate or/and glutamine or/and glutamate or/and ornithine of alpha-ketoglutarate.
Patent CA-2593851-A1 (CA)
Title: Registration and maintenance of address data for each service point in a territory
Inventor: OWENS TIMOTHY C
IPC: G06F17/30
Filed: 2006-01-27
Abstract: A computer system and method is disclosed for mining current and archived address data in order to identify a preferred address for each service point in a territory. The data mining system may start in response to the presentation of a candidate address for matching. The set of mined data may be prioritized by clustering like characteristics, building similarity matrices, and by constructing dendrograms with nodes joined according to common characteristics. A computer system and method for maintaining a central database of preferred addresses is also disclosed. Selected address data gathered in a queue may be scored by characteristic, grouped by consignee location, and staged for processing. The scored queue of data may be prioritized by clustering like characteristics, building similarity matrices, and by constructing dendrograms.
Patent CA-2594220-A1 (CA)
Title: Moisture removal system
Inventor: FERNANDES JOAO PASCOA
IPC: F24F3/14
Filed: 2007-06-15
Abstract: A sheathing layer spans a supporting surface from which moisture is to be removed. In one exemplary system, ventilation channels extend between opposed ends of the substrate layer, communicating with an outlet opening at one end and with a duct at the opposing end which in turn communicates with an inlet opening at the same end of the substrate layer as the outlet opening. A fan is arranged to circulate air through channels from the inlet opening to the outlet opening to replace humid air in the channels with drier replacement air. In another example, a substrate layer includes ventilation channels communicating only between the supporting surface and an outlet opening. The outlet opening connects to a fan which maintains the channels at a vacuum pressure to withdraw moisture therefrom.
Patent CA-2594885-A1 (CA)
Inventor: SCHULTZ MARK ALAN
IPC: G06T7/00
Filed: 2005-01-27
Abstract: A method and a system accomplish inspection of a mark in a frame of a film print. The system can include a frame imager which automatically selects at least one frame in the film print having an FMS mark and automatically captures an image of the frame. The image can be captured prior to, or subsequent to, the print being developed. The system also can include a marker which marks the frame with the mark. Further, the system can include a processor which automatically extracts the mark from the captured image and automatically compares the mark on the frame to a reference mark. The captured image can be stored to a database.
Patent CA-2599126-A1 (CA)
Inventor: JONES RODNEY
IPC: H02J3/40
Filed: 2007-08-28
Abstract: The present invention provides a method of controlling a power converter that can be used to interface to a power grid or supply network operating at a frequency (Fnet) that is nominally fixed (say at 50 Hz, for example) but which can be varied as a way of controlling power imbalanced within the network as a whole. The power converter can include a network bridge that operates in accordance with the pulse width modulation (PWM) strategy having a switching frequency (Fpwm), a nominal switching frequency (Fpwm_nom) and a number of pulses per period (Pulse_Number). The method comprising the step of varying the switching frequency (Fpwm) of the PWM strategy in accordance with the time-varying frequency (Fnet) of the supply network to achieve only integer odd harmonics of the time-varying frequency (Fnet) and adjusting the number of pulses per period (Pulse Number) in accordance with the time-varying frequency (Fnet) of the supply network to maintain a switching frequency (Fpwm) that is less than, or equal to, the nominal switching frequency (Fpwm_nom).
Patent CA-2602235-A1 (CA)
Title: Dispersion
Inventor: KEIJZER DE AUGUSTINUS EUGENE H
IPC: C09D135/06
Filed: 2006-04-06
Abstract: The invention relates to a dispersion of melamine powder in a liquid or an aminoplast resin in a liquid, whereby the dispersion contains a dispersant, said dispersant comprising a styrene-maleic anhydride copolymer. The invention further relates to a method for preparing the said dispersant, and to its use in adhesive compositions, coatings or laminates.
Patent CA-2602489-A1 (CA)
Title: Material moisture content adjustment method
Inventor: SASAKURA TAKESHI
IPC: B01F23/80
Filed: 2006-03-27
Abstract: When making moisture content adjustment by adding liquid such as water to a raw material such as pulverulent material including bentonite, uniform mixing of the liquid such as water with the raw material is given with relatively simple facilities, moisture content adjustment of a large quantity of raw materials is attainable, and besides, a material having satisfactory performances such as impermeability is obtainable through uniform moisture content adjustment. Within a mixing tank (1) configured with a normal powder mixer kept at low temperatures, pulverulent bentonite (A) and fine granular ice (B) are stirred and mixed. Stirring and mixing of the fellow pulverulent materials are adapted to uniformly mix the pulverulent bentonite (A) and the fine granular ice (B), enabling uniformly moisture content-adjusted bentonite to be obtained. A liquid-nitrogen gas bomb (21), for instance, is connected to the mixing tank (1), causing the inside of the mixing tank to be kept at low temperatures with nitrogen gas supplied from the bomb, before putting the prepared fine granular ice (B) through an inlet port (20).
Patent CA-2602494-A1 (CA)
Title: Liquid-filled chewing gum composition
Inventor: JANI BHARAT
IPC: A23L27/20
Filed: 2006-05-10
Abstract: Some embodiments provide a chewing or bubble gum composition which includes a liquid fill composition and a gum region which includes a gum base surrounding the liquid fill which may include a modified release component, wherein the gum region includes a polyol composition including at least one polyol and having a water solubility of less than 72% by weight at 25~C. The composition may also include a coating region which surrounds the gum region.
Patent CA-2605024-A1 (CA)
Inventor: JOHNSON LESLIE S
IPC: A61K39/395
Filed: 2006-04-17
Abstract: The present invention is directed to diabody molecules and uses thereof in the treatment of a variety of diseases and disorders, including immunological disorders, infectious disease, intoxication and cancers. The diabody molecules of the invention comprise two polypeptide chains that associate to form at least two epitope binding sites, which may recognize the same or different epitopes on the same or differing antigens. Additionally, the antigens may be from the same or different molecules. The individual polypeptide chains of the diabody molecule may be covalently bound through non-peptide bond covalent bonds, such as, but not limited to, disulfide bonding of cysteine residues located within each polypeptide chain. In particular embodiments, the diabody molecules of the present invention further comprise an Fc region, which allows antibody-like functionality to engineered into the molecule.
Patent CA-2605519-A1 (CA)
Title: Masking article and method of masking a substrate to be coated
Inventor: MOSZER MICHAEL J
IPC: B05B15/04
Filed: 2006-04-17
Abstract: The present disclosure relates to a profiled masking article and method of masking a substrate to be treated or painted that provides a feathered or soft edge between painted and unpainted areas. The masking article described herein may be used as a single strip, or as multiple strips, placed side by side, wherein a strip is removed between treatments of different types. This allows successive treatment layers to completely cover previous layers, thus avoiding defects resulting from exposed layers of material. In an embodiment, the present disclosure is directed to a masking article comprising: at least one elongate body (12), said body (12) having a top surface, a bottom surface and at least two lateral surfaces, wherein at least a portion of said body comprises an adhesive material; and a generally planar top portion (14), connected to the body along at least one surface, said top portion (14) having a microstructured surface.
Patent CA-2606891-A1 (CA)
Inventor: VAES ED
IPC: B26B1/08
Filed: 2007-10-15
Abstract: A knife including body including a blade head at one end and demountable roller at the other end, the blade head including a planar first guide cheek and planar second guide cheek, positioned at an angle, alpha relative a blade which is received between the first and second guide cheeks; a device for urging the blade between a retracted position and an extended position. The knife further including a device for attaching the roller to a roller end of the knife body, wherein the roller further including a right wheel half and a left wheel half such that the roller being comprised of two halves in intimate contact with each other.
Patent CA-2610973-A1 (CA)
Title: Carboxylated latex particles
Inventor: MORITZ HANS-ULRICH
IPC: G01N31/16
Filed: 2006-06-29
Abstract: The present invention relates to processes for preparing carboxylated latex particles based on the copolymerization of a monoalkenylaromatic monomer (A) and an aliphatic unsaturated carboxylic acid (B), where the copolymerization takes place at a pH in the range from pH >1.5 to pH <4.5. The pH is typically monitored during the copolymerization process and regulated by suitable compensatory titration. The invention likewise relates to the carboxylated latex particles obtainable by one of the processes according to the invention, and to the use of these particles in an immunological test method.
Patent CA-2611685-A1 (CA)
Inventor: CARLIN MATS STEFAN
IPC: G06V10/70
Filed: 2006-06-14
Abstract: The present invention is related to a method and system providing a pattern-classifier encoded dictionary for use in language processing systems implemented in computer systems. The pattern encoded dictionary according to the present invention may be utilized in Optical Character Recognition systems or (OCR) or Automatic Speech Recognition systems (ASR) to retrieve reliably identified words used in an adaptive manner or as a tool to configure said OCR  or ASR system.
Patent CA-2612125-A1 (CA)
Title: Highback with textile-like material for support
Inventor: CUNNINGHAM CHRISTOPHER C
IPC: A63C9/00
Filed: 2007-11-23
Abstract: A highback is provided for controlling a gliding board, such as a snowboard, through leg movement of a rider. The highback is comprised of an upright support member to support a rear region of the rider's leg. The highback includes a textile-like material that extends across a portion of the support member to provide support for a portion of the rider's leg. The support member may have an opening therein with the textile-like material extending across the opening to assist in transmitting forces applied to that region of the support member as the rider presses against the highback during riding maneuvers. The textile-like material may help to distribute forces across a larger area of the rider's leg or boot so as to reduce pressure points against the rider's leg. The textile-like material may include one or more filaments, a fabric, or a fabric-like material that is coupled to the support member to support the rider's leg. The textile-like material may include a mesh fabric.