baber/WOPTO huggingface dataset:
Patent DE-69434708-D1 (DE)
Inventor: ACRES BRUCE
IPC: A61K35/76
Filed: 1994-09-28
Granted: 2006-05-24
Abstract: Use of a viral vector contg. in its genome a DNA fragment (I) contg. ≥ 1 gene encoding all or part of an agent (A) that modulates the immune and/or inflammatory response for the treatment of cancer in mammals is new. (A) can be a cell surface co-stimulatory molecule, a chemokine, a monoclonal antibody against a lymphocyte surface maker, a super antigen characteristic of an infectious organism (bacterium, virus or parasite), a polypeptide with adjuvant activity or esp. a cytokine. Also claimed is the use of a viral vector with positive tropism for cancer cells contg. in its genome a DNA fragment including ≥ 1 gene, encoding an agent able to destroy cancer cells, under control of appropriate expression elements, for selective delivery of the agent to cancerous tumours.
Patent DE-69435109-D1 (DE)
Inventor: PLESKO GEORGE A
IPC: H03K17/96
Filed: 1994-10-27
Granted: 2008-08-14
Abstract: A high speed non-contact beam scanning device sized and shaped to provide the ergonomic benefits of a pen or wand, yet can scan a wide angle moving beam across an information-bearing target in one or two dimensional scan patterns such as lines, rasters or other patterns in order to read information therefrom. The device is well suited for reading one or two dimensional bar-code or other printed matter. In order to achieve the high density optical packaging necessary for its high performance to size benefits the device employs a novel in-line or "axial" gyrating, or "axial" scan element. The axial scan element can accept an input light beam at one end and cause it to emerge from its opposite end as a scanned beam, propagating in the same general forward direction it had upon entering the element. Reflected light, which carries information contained on the target, is collected by an internal non-imaging light concentrator and is processed by signal processing electronics. All components are integrated into a thin low mass module small enough to fit in a pen. Communication from the device is achievable by a cable or by wireless transmission.
Patent DE-69518445-D1 (DE)
Inventor: COLLINS DEBORAH LYNN
IPC: G09B5/00
Filed: 1995-05-24
Granted: 2000-09-21
Abstract: A method and apparatus is provided for automated learning and performance evaluation of a group of items by a user. The method, which can be practised on a digital computer, has steps of querying the user as to whether items are believed to be known or unknown, sorting the items into groups of perceived known and unknown items and generating a sequence of items to be displayed. The apparatus e.g. a digital computer, has input means for receiving a user's response, a display means for presenting the material to be learned and logic means for sorting the items. An important feature of this invention is that the user is tested regarding his belief as to whether the item is known or unknown, not as to his actual knowledge.
Patent DE-69525479-D1 (DE)
Inventor: VACCARO D
IPC: C07D403/12
Filed: 1995-12-18
Granted: 2002-03-21
Abstract: 4-[(Heterocycloalkyl or heteroaromatic)-substituted phenyl]-2-azetidinone hypocholesterolemic agents of the formula    <IMAGE>  I  or a pharmaceutically acceptable salt thereof, wherein: A is optionally substituted heterocycloalkyl, heteroaryl, benzofused heterocycloalkyl, or benzofused heteroaryl; Ar1 and Ar2 are optionally substituted aryl; Q is a bond or, with the 3-position ring carbon of the azetidinone, forms a spiro group; and R1 is alkylene; alkylene wherein a carbon in the chain is replaced by -O-, -C(O)-, phenylene, -NR8-, -S(O)0-2- or cycloalkylene; or alkenylene; or, when Q is a bond, R1 can be alkylene substituted by one or two hydroxy groups or hydroxy derivatives, wherein the alkylene chain can optionally be joined to Ar1 through -O- or -S(O)0-2- or joined to the azetidinone ring through a -S(O)0-2- group; a method of lowering serum cholesterol by administering said compounds, pharmaceutical compositions containing them, and the combination of a substituted azetidinone and a cholesterol biosynthesis inhibitor for the treatment and prevention of atherosclerosis.
Patent DE-69527375-D1 (DE)
Inventor: HELLER MICHAEL J
IPC: C12Q1/6825
Filed: 1995-09-06
Granted: 2002-08-14
Abstract: A system for performing molecular biological diagnosis, analysis and multi-step and multiplex reactions utilizes a self-addressable, self-assembling microelectronic system for actively carrying out controlled reactions in microscopic formats. These reactions include most molecular biological procedures, such as nucleic acid hybridization, antibody/antigen reaction, and clinical diagnostics. Multi-step combinatorial biopolymer synthesis may be performed. A controller interfaces with a user via input/output devices, preferably including a graphical display. Independent electronic control is achieved for the individual microlocations. In the preferred embodiment, the controller interfaces with a power supply and interface, the interface providing selective connection to the microlocations, polarity reversal, and optionally selective potential or current levels to individual electrodes. A system for performing sample preparation, hybridization and detection and data analysis integrates multiple steps within a combined system.
Patent DE-69533597-D1 (DE)
Inventor: DEVRIES DOUGLAS F
IPC: A61M16/00
Filed: 1995-07-05
Granted: 2004-11-04
Abstract: An exhalation valve for controlling the expiratory gas flow from a mammalian patient, said exhalation valve comprising:a housing defining an expiratory gas flow passageway therethrough;a valve seat formed within said expiratory gas flow passageway;an annular diaphragm movably disposed within said gas flow passageway, in juxtaposition to said valve seat, said diaphragm being variably movable back and forth to various positions between and including:i) a fully closed position wherein said diaphragm is firmly seated against said valve seat to prevent gas from flowing through said passageway; andii) a fully open position wherein said diaphragm is retracted away from said annular valve seat so as to permit substantially unrestricted flow of expiratory gas through said pathway;an elongate actuation shaft having a proximal end and a distal end, the distal end of said actuation shaft being contactable with said diaphragm, and said actuation shaft being axially moveable back and forth to control the positioning of said diaphragm between said fully closed and said fully open positions;an electrical induction coil linked to said actuation shaft such that a decrease in the current passing into said induction coil will cause said shaft to advance in the distal direction and an increase in the current passing into said induction coil will cause said shaft to retract in the proximal direction;means for determining airway pressure;a microprocessor controller connected to said means for determining airway pressure, said controller being provided with a positive expiratory pressure setting, and said controller being connected to said induction coil and adapted to emit control signals to said induction coil to control the movement of said actuation shaft in response to the current airway pressure, thereby maintaining the present amount of positive expiratory pressure;a radio frequency transponder database containing flow characterisation data for the means for determining the flow rate of expiratory gas passing out of said exhalation valve;said controller being further connected to said means for determining the flow rate of expiratory gas passing out of said exhalation valve and being equipped to receive radio frequency input of the characterisation data contained in the radio frequency transponder database, and to utilise such data to determine the instant flow rate of expiratory gas passing out of said exhalation valve.
Patent DE-69602887-D1 (DE)
Inventor: BONNER LYDIA M
IPC: G01N35/04
Filed: 1996-04-23
Granted: 1999-07-22
Abstract: Fluid sensor dispenser comprises a magazine (26) with slots holding sensors (38) and located in a housing (22) opening, and an actuator (58) to advance through a slot to place the sensor in position of use. After use the actuator can be moved further to eject the used sensor and in returning to standby position activates an indexing drive (56) to turn the magazine and place the next sensor in ready position. The magazine is pref. a right cylinder with detent along its outer periphery each corresponding to one slot and with detents and slots equally spaced. The magazine pref. also has cavities holding desiccant and each communicating with one slot.
Patent DE-69608264-D1 (DE)
Inventor: TONKIN W
IPC: H04N7/52
Filed: 1996-03-21
Granted: 2000-06-15
Abstract: A system for bi-direction digital serial communication and control of remote units including video cameras and input/output devices in machine vision systems. The communication system includes a main processor, communication hubs and remote units. The system is capable of monitoring and controlling the remote units in real-time while receiving video data images from the remote video cameras. Digital signals are transmitted in two different protocols; one for data communications, and one for control communications. If a high priority control signal is detected during transmission of a data packet, the transmission is interrupted, the high priority control signal is transmitted, and the transmission of the data packet is thereafter completed. <IMAGE>
Patent DE-69617479-D1 (DE)
Inventor: FRANCO RAFFAELE
IPC: C08L23/04
Filed: 1996-01-05
Granted: 2002-01-17
Abstract: Composition obtained by means of the dynamic crosslinking of:   (A) an ethylene-butene copolymer, possibly also containing propylene with a density equal to, or lower than, 0.9 g/cm<3>, in a % amount comprised within the range of from 90 to 50% by weight; (B) at least one polyolefin or an ethylene-propylene copolymer with a density of round 0.9 g/cm<3>, in a % amount comprised within the range of from 10 to 50% by weight.
Patent DE-69622275-D1 (DE)
Inventor: TYAN B
IPC: C12Q1/68
Filed: 1996-08-16
Granted: 2002-08-14
Abstract: In accordance with the present invention, there are provided isolated nucleic acids useful in diagnostic methods and kits for detecting a genetic predisposition for seronegative spondyloarthropathies.
Patent DE-69625691-D1 (DE)
Inventor: COSTANZO J
IPC: A61P7/02
Filed: 1996-06-03
Granted: 2003-02-13
Abstract: Compounds of the Formula I:    <IMAGE>  I  useful in the treatment of thrombin and trypsin related disorders.
Patent DE-69628540-D1 (DE)
Inventor: DYER CONRAD
IPC: C07B55/00
Filed: 1996-01-12
Granted: 2003-07-10
Abstract: An optically-enriched piperidine-2-carboxanilide compound, in which the piperidine is optionally N-alkylated, is racemised by heating the compound in an aqueous medium, provided that the medium includes an organic cosolvent if the compound is N-alkylated. This process is particularly valuable, in conjuction with a resolution process, for the manufacture of levobupivacaine.
Patent DE-69637503-D1 (DE)
Inventor: VAN DEN BERG DAVE
IPC: B29C45/14
Filed: 1996-10-10
Granted: 2008-05-29
Abstract: An encapsulated transducer (10) includes an injection molded encapsulation (20) having front end (22) and back end (24). The encapsulation (20) is a monolith of cured moldable material ensconcing a sensing element or coil (90) proximate front end (22) and a portion of an information transmitting medium (120) emanating from back end (24). A component alignment preform (40) operatively couples sensing element (90) with information transmitting medium (120). A protective sleeve (150) is transfer molded over coil (90) and interlocked with preform (40) thereby forming a sleeved coil and cable assembly (170). This sleeved coil and cable assembly (170) is encapsulated by an injection molding process which provides the durable encapsulation (20). The sleeved coil and cable assembly (170) is symmetrically disposed within the encapsulation (20) and the encapsulation (20) includes an integrally formed protective wall having a uniform thickness "T" along a forwardmost portion of sensing element (90) and integrally transitioning into an uninterrupted side wall circumscribing the sensing element and a portion of the cable.
Patent DE-69703109-D1 (DE)
Inventor: BELLESORT STEPHANE
IPC: A61K6/891
Filed: 1997-05-28
Granted: 2000-10-19
Abstract: Dental prosthesis composed of a polymer containing hydrogen atoms and with the required mechanical and chemical properties, characterized in that the hydrogen atoms on the surface of the said polymer are partially replaced by fluorine atoms in the CF, -CF2 -CF3, -OH, -COOH, -C=O, -OOH, -NH2, -C=NH or CONH2 groups. This type of polymer can improve the retention of prostheses and/or limit the development of dental plaque.
Patent DE-69716076-D1 (DE)
Inventor: PETERSSON BENGT
IPC: F16K15/20
Filed: 1997-07-04
Granted: 2002-11-07
Abstract: The present invention relates to a non return valve which is provided by welding two lines in two flat upon each other lying film surfaces, which are then folded towards each other and after that they are joined together around the outer edges except the opening channel so that over pressure is formed when the container is filled completely or partly and then the non return valve starts to operate with safe sealing. The opening channel is formed between two against each other lying sections of film material, which sections extend from the outside of the container into it and are joined together right up to the opening channel.
Patent DE-69721721-D1 (DE)
Inventor: YAMADA IKUDO
IPC: A61F13/15
Filed: 1997-06-06
Granted: 2003-06-12
Abstract: A multi-layer sanitary napkin (10) comprising a plurality of ordinary sanitary napkins (1) for menses or leukorrhea which are supplied in a single-use form, each being provided with an absorbing surface and a rim, wherein the ordinary napkins are piled with respective absorbing surfaces thereof directed upward, and peelably joined with each other into unity at the rims by bonding, embossing or simultaneous bonding and embossing. Each of the ordinary napkins contained therein can be shaped as concave as a ship's bottom, to shape the entire figure of the multi-layer sanitary napkin in the same manner. The multi-layer sanitary napkin can further comprise pull tabs (3) formed on either end of respective ordinary napkins, each tab being formed not so as to overlap on neighboring ones. <IMAGE>
Patent DE-69722391-D1 (DE)
Inventor: MEAD JOHN
IPC: C12M1/34
Filed: 1997-03-12
Granted: 2003-07-03
Abstract: PCT No. PCT/GB97/00669 Sec. 371 Date Sep. 11, 1998 Sec. 102(e) Date Sep. 11, 1998 PCT Filed Mar. 12, 1997 PCT Pub. No. WO97/33973 PCT Pub. Date Sep. 18, 1997A process of culturing a microorganism in a culture medium in which process the addition of feed medium is controlled by using the production of a by-product as a measure of the culture conditions, characterized in that the by-product is an electrically charged metabolite produced by the microorganism, and in that the production of the metabolite is monitored by measuring the conductance of the culture medium. The metabolite may be acetate and the microorganism may be yeast which is genetically engineered to produce a desired polypeptide.
Patent DE-69728354-D1 (DE)
Inventor: TSUKUDA AKIMITSU
IPC: G11B5/733
Filed: 1997-04-17
Granted: 2004-05-06
Abstract: The present invention relates to aromatic polyamide film which is characterized in that on at least one face thereof the number of projections of height at least 20nm but less than 50nm is from 10<3> to 10<6> per mm<2>, and the number of projections of height at least 50nm but less than 100nm is from 0 to 3 x 10<4> per mm<2>. Further, the present invention also offers a method of producing an aromatic polyamide film which is characterized in that, in a method of producing aromatic polyamide film from a solution obtained by adding to an aromatic polyamide solution a particle-containing slurry formed by dispersing particles of particle diameter 10 to 300nm in a liquid medium of 10 poise or less, such that the amount of said particles added in terms of the aromatic polyamide is 0.005 to 4.5wt%, the relative standard deviation in the diameters of said particles is no more than 0.8 and, furthermore, there is used a particle-containing slurry where the initial filterability index Q1 of said particle-containing slurry and the filterability index Q2 after the passage of 500ml of liquid satisfy the following relation. <MATH>   While the film of the present invention is also ideal for use as flexible printed substrates, capacitors and printer ribbons, etc, since it is possible to realise extremely high levels of both output characteristics and durability, it is especially suitable for magnetic recording media, in particular for computer external memory and digital video tape where high density and high precision are demanded.
Patent DE-69800623-D1 (DE)
Inventor: COLE THEODORE JOHN
IPC: A01K39/00
Filed: 1998-10-27
Granted: 2001-04-26
Abstract: A feeder assembly (10) for birds or other animals having a pan member (26), a feeder tube (20) defining a channel (42) for receiving feed from a feed supply, a plurality of wing members (22) having a plurality of fingers (92) for adjustably engaging the feeder tube (20), and a cone member (24) disposed about the feeder tube (20) and slidably mounted to the plurality of wing members (22) by a plurality of engaging arms (110). The cone member (24) is adapted to slide relative to the feeder tube (20) between a lowered position and a raised position. The pan member (26) and an end (32) of the cone member (24) define a feed opening (30) for permitting feed to pass from the feeder tube (20) to the pan member (26) for presentation. The feed opening (30) can be adjusted in size by either adjusting the wing members (22) relative to the pan member (26) or by sliding and adjustably positioning the cone member (24) relative to the feeder tube (20) and the wing members (22). <IMAGE>
Patent DE-69803817-D1 (DE)
Inventor: STIRM MICHAEL
IPC: B25D16/00
Filed: 1998-07-14
Granted: 2002-03-21
Abstract: A rotary hammer with a hammer housing and a hammer mechanism provided therein has a tool holder (40) releasably fitted onto the front section of the hammer spindle (6) for receiving a hammer bit (41) with limited axial movement and non-rotatably. Arranged coaxially with respect to the section of the hammer spindle is a drill spindle (30), beyond the front end of which the section of the hammer spindle (6) receiving the tool holder (40) projects, and to which a drill chuck (42) for receiving an insert tool without axial displacement can be releasably and non-rotatably attached. The drill spindle (30) is driven by an additional rotary drive which operates when the electric motor is actuated, and the rotational speed of the drill spindle (30) is higher than the rotational speed of the hammer spindle (6) . <IMAGE>
Patent DE-69817821-D1 (DE)
Inventor: LEON L
IPC: G01M3/24
Filed: 1998-06-18
Granted: 2003-10-09
Abstract: A method and apparatus for on-line detection of leaky emergency shutdown or other valves in a fluid transport system having an upstream pipe, a downstream pipe and the valve connected between the upstream pipe and the downstream pipe for controlling fluid flow through the system. The valve has at least one upstream seal and at least one downstream seal and an inner cavity effectively isolated by the seals from the fluid flow stream through the system. The apparatus comprises a first transducer in fluid communication with the fluid flow stream at at least one of: a predetermined distance upstream of the upstream seal; and a predetermined distance downstream of the downstream seal. The first transducer is for sensing pressure pulsations resulting from at least one of: dynamic energy due to fluid flow through the transport system; and transient energy within the fluid in the transport system after the valve is closed and for generating representative electrical signals as a function of time. A second transducer is in fluid communication with the inner cavity of the valve for sensing substantially simultaneous pressure pulsations within the inner cavity and for generating second representative electrical signals as a function of time. An analyzer receives the first and second electrical signals and generates at least one of: a frequency response function; and a coherence function. The generated function is sufficiently averaged to provide a meaningful measure of the degree to which the two electrical signals are related to thereby indicate whether, and to what extent, sensed pressure pulsations within the fluid transport system are passed through at least one of the seals to the inner cavity.
Patent DE-69906563-D1 (DE)
Inventor: RASMUSSEN VILLEFRANCE
IPC: D06P3/00
Filed: 1999-08-16
Granted: 2003-05-08
Abstract: A pattern carrier for use in transfer pattern printing of textiles comprises paper with an air permeability (Bendtsen-porosity) of more than 500 ml/min and a water absorption corresponding to a Cobb-number of at least 50, said paper being coated with an aqueous dispersion of carboxymethylcellulose containing a non-crystallizing saccharide syrup, preferably in an amount of approximately 30 g of dispersion per m<2>, whereafter one or more color pattern are printed on said paper, each color pattern comprising a water-soluble or dispersible dye admixed an easily soluble thickening carrier with a temporary binding effect, preferably in form of carboxymethylcellulose. The use of a saccharide syrup, preferably a sorbitol syrup, for the coating renders it possible to use standard-absorbing crude paper as the basis of the pattern carrier, which provides obvious financial and production-related advantages.
Patent DE-69907725-D1 (DE)
Inventor: VAN DUIN MARCEL
IPC: A61P15/08
Filed: 1999-11-25
Granted: 2003-06-12
Abstract: The present invention relates to the use of GDF-9 in assisted reproduction and to kits comprising GDF-9. A method is provided to stimulate follicle and oocyte development and maturation. The method comprises administering GDF-9 in combination with gonadotropins.
Patent DE-69922146-D1 (DE)
Inventor: ALEXANDER D
IPC: C10G57/00
Filed: 1999-09-03
Granted: 2004-12-30
Abstract: A product of reduced sulfur content is produced from a feedstock which is comprised of a mixture of hydrocarbons and includes sulfur-containing aromatic compounds as unwanted impurities. The process involves separating the feedstock by fractional distillation into a lower boiling fraction which contains the more volatile sulfur-containing aromatic impurities and at least one higher boiling fraction which contains the less volatile sulfur-containing aromatic impurities. Each fraction is then separately subjected to reaction conditions which are effective to convert at least a portion of its content of sulfur-containing aromatic impurities to higher boiling sulfur-containing products by alkylation with an alkylating agent in the presence of an acidic catalyst. The higher boiling sulfur-containing products are removed by fractional distillation.
Patent DE-69925551-D1 (DE)
Inventor: MERRITT ADRIAN LLEWELLYN
IPC: B65H37/00
Filed: 1999-09-06
Granted: 2005-07-07
Abstract: A method of separating first and second flexible elongate plys (4,6) adhered together by adhesive force overcomable to allow the plys to be peeled apart comprising constraining the adhered plys (8) to follow a path leading to a turn at or adjacent to which turn the first ply (4) on the inside of the turn peels away from the second ply (6) on the outside thereby causing the plys to separate. A force may be applied to one of the first or second plys (4,6), which compels the ply to move along its path. The remaining ply is preferably allowed to fall away from the turn. The turn may be substantially 90 DEG , or greater or less than this. An apparatus to separate the first and second flexible elongate plys (4,6) is also provided. <IMAGE>