baber/WOPTO huggingface dataset:
Patent NZ-335489-A (NZ)
Title: Method for the detection of compounds that modulate the effects of the obese (OB) protein
Inventor: BEELEY LEE JAMES
IPC: C12Q1/68
Filed: 1997-10-30
Abstract: A method for the detection of a compound that mimics, potentiates or inhibits the physiological effect of the ob-protein comprises: a) for a compound which mimics the physiological effect of the ob-protein: assessing the effect of the compound upon an ob-protein activated signal transducer and activator of transcription (STAT) DNA response element coupled to a reporter gene or b) for a compound which potentiates or inhibits the physiological effect of the ob-protein: assessing the effect of the compound upon the response provided by ob-protein upon an ob-protein activated STAT DNA response element coupled to a reporter gene; wherein the response element and the reporter are expressed in an ob-protein responsive cell line selected from i) a hypothalamic derived cell line; ii) a pheochromocytoma derived cell line; iii) a haematopoietic derived cell line; iv) a pancreatic derived cell line; v) a liver derived cell line; vi) a preadipocyte derived cell line; vii) a skeletal muscle derived cell line and viii) an ovarian derived cell line; or the response element and the reporter are expressed in a cell line which is also transfected with a polypeptide capable of mediating the stimulation by ob-protein of an ob-protein activated STAT DNA response element and contains the appropriate STAT proteins.
Patent NZ-337535-A (NZ)
Title: A device for controlled anaesthesia, analgesia and/or sedation using an emulsion containing inert gas
Inventor: GEORGIEFF MICHAEL
IPC: A61K9/00
Filed: 1998-03-06
Abstract: A device is disclosed for inducing anaesthesia, analgesia and/or sedation is described which comprises a container holding an inert gas-containing liquid preparation, and means for the controlled administration of the preparation to a patient.  The preparation has an emulsion containing inert gas.
Patent NZ-502128-A (NZ)
Title: Benzothiophene compounds and their use in treating neurological disorders
Inventor: DEL CASTILLO NIETO JUAN CARLOS
IPC: C07D333/32
Filed: 1998-07-01
Abstract: Thiophene and benzothiophene derivative compounds, the salts, optical isomers and polymorphs thereof, of the general formula (I) wherein: Z is: -CO-, -CH(OR6)-, -C(NOR7)-; R1 is H, alkyl, halogen, or -OR8; R2 and R3 are the same or different and are H, alkyl, halogen, nitro, cyano, -OR8, NR9R10, OR8; CO2R8, -SO2NR9R10, -SO2R8, SR8, cyano, -CONR9R10; R4 and R5 are the same or different and are H, alkyl, halogen, haloalkyl, -OR8, nitro, NR9R10, OR8, CO2R8, -SO2NR9R10, -SO2R8, SR8, cyano, -CONR9R10 or R4 and R5 together form a benzene ring fused to the phenyl ring; R6 is H, alkyl, CO2R8, -C(O)NR9R10, naphthyl or phenyl optionally substituted by one or more substituents selected from H, haloalkyl, alkyl, halogen, alkoxy, methylenedioxy, nitro, cyano; R7 is H or alkyl; R8 is H, alkyl or phenyl; R9, R10 are independent and stand for H, alkyl or phenyl, or together with the atom of N to which they are attached, form a 5- or 6-membered ring in which there may optionally be an atom of N, O or S; or a salt or a solvate, or a geometric isomer or an optical isomer thereof. The compounds are useful in the treatment of neurological disorders, particularly anxiety and depression.
Patent NZ-502736-A (NZ)
Title: Friction ball seismic and vibration energy absorber
Inventor: ROBINSON WILLIAM HENRY
IPC: E04B1/36
Filed: 1998-08-10
Abstract: A seismic and vibration isolation bearing assembly for buildings and structures. The bearing assembly (10) comprises a compressible friction ball (10) resting on a lower seat (12) with a structure (1) resting on top of the friction ball (10). The core (22) of the friction ball (10) comprises particulate material to resist rolling motion and is enclosed by layer (24). The contacting surfaces of the structure and lower seat may be flat or curved.
Patent NZ-502768-A (NZ)
Title: A method of endrounding loose fibres in the manufacture of brushes
Inventor: BOUCHERIE BART GERARD
IPC: A46B9/02
Filed: 1998-08-12
Abstract: A method for endrounding the fibres of thermoplastic material for use in brush making.  The fibres are presented to an endrounding tool in a tuft and the free ends of the fibres are exposed to a working surface of the tool.  The relative movement between the ends of the fibres of the tuft and the working surface causes the material of the fibres to be heated by friction.
Patent NZ-504556-A (NZ)
Title: Rigid pack of smoking articles with resealable barrier layer
Inventor: PARKER MICHAEL PATRICK
IPC: B60B37/10
Filed: 1998-12-02
Abstract: A rigid pack of smoking articles is made to have improved shelf life and to be resealable. A barrier material is sealed around the rigid pack. The rigid pack has a potential or actual access aperture extending from a top face into a major face. The barrier material has a line of severance or weakening defining a flap, which is in register with the potential or actual access aperture. Over the flap is a layer which overlaps it on each severable side with a portion having permanently-tacky adhesive. A non-adhered pull tab is preferably provided on the layer. To open the pack the user lifts the flap and if necessary the access aperture. After removal of a smoking article the gap in the barrier layer is reclosed and resealed by the repositioning of the adhesive layer, carrying with it the flap of barrier material. A machine for assembling the pack is also disclosed.
Patent NZ-505937-A (NZ)
Title: Recumbent bicycle
Inventor: GEORGE ALISTAIR GRANT
IPC: B62K3/10
Filed: 2000-07-24
Abstract: A bicycle including a frame having a longitudinal axis extending from adjacent a rear wheel to adjacent a front wheel, the frame having a bend therebetween to define an upwardly extending rear frame portion and a upwardly extending front frame portion, a cantilever support assembly extending downward from the rear frame portion and being adapted to rotatably support a rear wheel, a fork assembly extending downward from the front frame portion and being adapted to rotatably support a front wheel, a crankset assembly including a chainwheel and cranks mounted at the bend of the frame and being configured and arranged to drive the rear wheel, a seat assembly associated with the rear frame portion, the seat assembly adapted to allow a rider to mount the bicycle, a steering assembly being associated with the front fork assembly, in use to steer the bicycle.
Patent NZ-506998-A (NZ)
Title: Breathing exercise apparatus having the effect of increasing respiration rate from conditions such as chronic bronchitis, asthma, hypersecretion or mucous blockages characterised by a "J" or "L" shaped device with a rotable first portion and ball present in the second portion
Inventor: ALISON VICTORIA JANE
IPC: A63B23/18
Filed: 2000-09-15
Abstract: An expiration resisting apparatus for assisting pulmonary ventilation comprising or including: a) a substantially L-shaped tubular element having a first part and a second part said first part having an air inlet defined by a profiled mouthpiece into which a patient is able to exhale and a second part having an exhaust passage, the axis of said passage being inclined upwardly with respect to the axis of said first part, wherein said first part is rotatable with respect to said second part about a central axis through said first and second parts, b) a spherical ball moveable within said exhaust passage, c) a ball seat against which said ball rests to obstruct said exhaust passage prior to expiration, said ball able to be displaced freely in said passage and offering a resistance to the expiration of air exhaled by said patient by the effect of its own weight, d) ball retaining means for retaining said ball within said exhaust passage.
Patent NZ-507918-A (NZ)
Title: Recombinant baculovirus-based insecticides
Inventor: BRENNAN LYNN A
IPC: A01N63/40
Filed: 1999-05-07
Abstract: Isolated recombinant Plutella xylostella baculovirus for use as insecticides.  Preferably, a recombinant baculovirus which has incorporated within its genome a gene encoding an insecticidal toxin.  Also described are ligation vectors designed to introduce an insecticidal toxin gene into a Plutella xylostella baculovirus.  Further described are insecticidal compositions and formulations comprising recombinant Plutella xylostella baculoviruses and methods for killing insect pests and for reducing insect infestation of crops.
Patent NZ-508490-A (NZ)
Title: Use of a combination of a GABA analog and caffeine as an analgesic
Inventor: MAGNUS LESLIE
IPC: A61K31/522
Filed: 1999-06-18
Abstract: A GABA analog and caffeine combination is used to elicit an enhanced analgesic response.  The GABA analog can be either gabapentin or pregabalin.
Patent NZ-508528-A (NZ)
Title: Oxygen dispenser with flow control valve
Inventor: SIMLER DOMINIC ADAM
IPC: B01D53/00
Filed: 2000-11-30
Abstract: An oxygen dispenser operated by card or coins is disclosed.
Patent NZ-509605-A (NZ)
Title: Cheese ripening process using an attenuated bacterial starter culture obtained by treatment with a surface active agent
Inventor: SMITH MARK RODNEY
IPC: A23C19/032
Filed: 1999-06-29
Abstract: A method for accelerated cheese ripening using a primary starter culture and an attenuated bacterial starter culture.  The attenuated bacterial starter culture is treated with surface active agents.
Patent NZ-510652-A (NZ)
Title: Portable information terminal, method of processing audio data, recording medium, and program
Inventor: WAKIMURA TAKAYUKI
IPC: G10L19/02
Filed: 2000-07-10
Abstract: A portable information terminal and also a simplified audio coding program that is capable of quickly processing audio data. The terminal has a memory for data storage, including an expansion processor unit (202) with a unit (240) for defining one of two buffers (BUF1 and BUF2) as a present inverse quantisation buffer and defining one of two buffers (BUF11 and BUF12) as a present restoration buffer, a processor (246) for inversely quantising a value read for each sample from a DCT data buffer and another processor (248) for effecting an IDCT process on the inversely quantised data to revert frequency-domain data to time-domain audio data. A low-pass filter processor (250) is used to remove a high-frequency component from the time-domain audio data and there is included a further unit (252) to output successive samples of audio data to a DAC (156) to send sound to a speaker (184).
Patent NZ-512981-A (NZ)
Title: Use of pyridazino[4,5-b]indole-1-acetamide derivatives for treating diseases related to the dysfunction of peripheral benzodiazepine receptors
Inventor: FERZAZ BADIA
IPC: A61K31/407
Filed: 2000-01-21
Abstract: A compound of formula (I) is used to prevent or treat diseases and disorders linked to the dysfunctioning of peripheral-type benzodiazepine receptors wherein: X is halogen; Y is hydrogen or hydrogen, halogen, hydroxyl, methyl, methoxy or nitro; R1 is alkyl and R2 and R3 are independently hydrogen or alkyl, or R2 and R3 together with the nitrogen atom to which they are attached represent a pyrrolidinyl, piperidinyl or morpholinyl group.
Patent NZ-513186-A (NZ)
Title: Pesticide treatment containing two pesticides from the same chemical class
Inventor: MARTIN PAUL JOHN
IPC: A01N43/90
Filed: 2000-02-08
Abstract: A method of manufacturing a pesticidal composition having both a desired high level of efficacy and a residue level below the legally defined maximum allowable residue level comprises: i) selecting a chemical class of actives useful as pesticides such as avermectins, synthetic pyrethroids, benzimidazoles, benzophenol ureas or pyrazoles. ii) selecting a first active with a desired mode of action from the chemical class of actives; iii) selecting one or more subsequent active from the chemical class of actives having the same mode of action as the first active wherein each subsequent active differs chemically from the first active and from each others; iv) determining a reduced dosage level of each active until the resulting residue level of each active is below the legally defined maximum allowable residue level for that active having the desired mode of action and v) combining the first and each subsequent active with a suitable carrier until the additive effect of all the combined actives reaches the desired level of efficacy. An example of determining a reduced dosage level of each active is determining the LD 90 amount for each active and the desired level of efficacy can be a kill rate of LD 99 or greater. The first active can be abamectin and the second active can be ivermectin or the first active can be triflumuron and the second active can be diflubenzuron or the first active can be cypermethrin and the second active can be deltamethrin.
Patent NZ-513918-A (NZ)
Title: Nutritional composition intended for specific gastro-intestinal maturation in premature mammals
Inventor: GARCIA-RODENAS CLARA L
IPC: A23L33/15
Filed: 2000-03-01
Abstract: A nutritional enteral composition intended for favouring the growth and maturation of non-mature gastro-intestinal tracts of young mammals, which contains: (I) a mixture of dietary protein hydrolysates in the form of a mixture of different size peptides and free amino acids, and (II) intact proteins being partly in form of bioactive peptides.
Patent NZ-514999-A (NZ)
Title: Coating compositions containing highly structured macromolecules
Inventor: CORCORAN PATRICK HENRY
IPC: C09D201/06
Filed: 2000-05-02
Abstract: A coating composition comprising: a crosslinking component comprising a polyamine, a polyketimine, or a combination thereof, wherein the polyamine has an average of at least two amine functionalities per polyamine molecule and wherein the polyketimine has an average of at least two ketimine functionalities per polyketimine molecule, and a binder component comprising at least one structured reactive diluent having a GPC weight average molecular weight in the range of 100 to 50 000, the diluent being substantially free from acrylate functionalities and having at least two acetoacetate functionalities per diluent molecule. The coating composition is intended as a low VOC ambient temperature curable coating composition suitable for use in automotive refinish applications.
Patent NZ-516743-A (NZ)
Title: Methods for treating or preventing pain and anxiety
Inventor: WICKENDEN ALAN DAVID
IPC: A61P17/02
Filed: 2000-08-04
Abstract: Use of the following compounds to reduce pain by increasing ion flow through the KCNQ potassium channels in a cell.
Patent NZ-522709-A (NZ)
Title: Topical composition for the treatment of psoriasis and related skin disorders comprising glucosamine and herbal extracts of berberine and oleuropein
Inventor: MEISNER LORRAINE F
IPC: A61K36/87
Filed: 2001-05-01
Abstract: Disclosed are topical skin preparations comprising glucosamine and at least one antioxidant anti-inflammatory from a herbal source in an emollient base. Preferably the herb extracts are berberine and/or oleuropein. The formulations can be used in the manufacture of a medicament for the treatment of inflammatory skin cell disorders related to T-cell activation, such as psoriasis and dermatitis.
Patent NZ-523183-A (NZ)
Title: Isolated cationic, polyphemusin-like peptideS having two anti-parallel beta strands stabilized by two disulfide bonds, a beta hairpin loop and antimicrobial activity useful to inhibit microbial growth
Inventor: HANCOCK ROBERT
IPC: A61P31/04
Filed: 2001-06-27
Abstract: A class of cationic, polyphemusin-like peptides having antimicrobial activity is provided. Examples of such peptides include FRWCFRVCYKGRCRYKCR (SEQ ID NO: 3), RRWCFRVCYKGFCRYKCR (SEQ ID NO: 4), and RRWCFRVCYRGRFCYRKCR (SEQ ID NO: 11). Also provided are methods for inhibiting the growth of microbes such as bacteria, yeast and viruses utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.
Patent NZ-524345-A (NZ)
Title: Composition for the prevention and/or treatment, in newborn babies, of the effects of complications during childbirth
Inventor: PEETERS CACHA MARIE PETRONELLE
IPC: A61K31/17
Filed: 2001-03-30
Abstract: A selective inhibitor of neuronal nitric oxide synthase (nNOS) and of inducible nitric oxide synthase (iNOS), which does not substantially inhibit endothelial nitric oxide synthase (eNOS), can be effectively used for the treatment, in human or other mammalian neonates, of the effects of complications during childbirth. Such effects include perinatal asphyxia and hypoxia-ischemia. A very useful example of such a selective inhibitor is 2-iminobiotin.
Patent NZ-526489-A (NZ)
Title: An in vivo method for producing female offsprings in mammals using a material comprising acetic acid
Inventor: AULAKH BALWINDER SINGH
IPC: A61D19/00
Filed: 2000-12-15
Abstract: An in vivo method for production of female offsprings in non-human mammals such as cows, buffaloes, pigs, sheep, dogs, horses, and goats is disclosed, wherein the method comprises the step of administering a therapeutically effective amount of a material essentially consisting of acetic acid and/or its pharmaceutically acceptable derivatives by a route selected from oral, parenteral, anal, and cutaneous, after or before insemination.
Patent NZ-527608-A (NZ)
Title: Plug and gland aseptic package system
Inventor: ANDERSON IAN MCARTHUR
IPC: B65D39/04
Filed: 1999-06-25
Abstract: A sterilisation and filling apparatus, method and plug arrangement for aseptic filling of sterile containers. The apparatus includes a filling nozzle comprising a tubular body (16) with a flow passage (19) therethrough and a plug (22) closing the flow passage; a sterilisation and filling head (39) movable towards and away from the tubular body with outer (40) and inner (42) annular sealing rings engaging annular sealing faces on the tubular body and plug respectively and a sterilisation chamber (44) located inwards of the outer sealing ring, and a cavity in the filling head to receive the plug. Sterilisation fluid supply means supplies fluid to the chamber (44). Plug extractor jaws (70) extract the plug (22) from the tubular body (16) and store the plug in the cavity in the head and filling means fill the container through the head. The plug (22) includes gripping formations for the jaws (70). The plug (22) and tubular body (16) may include ribs and recesses as retaining means and sealing welds or elastomeric rings cooperative before and/or after filling. (62) Divided out of 509001
Patent NZ-529554-A (NZ)
Title: Dairy product and process
Inventor: ELSTON PETER DUDLEY
IPC: A23L27/24
Filed: 2003-11-14
Abstract: Disclosed herein is a process for preparing cheese that comprises (a) providing a protein concentrate; (b) providing a flavour concentrate using at least one strain of organism, (c) mixing the protein concentrate with a source of fat and/or liquid if required, (d) heating to form a coagulated cheese mass without holding for fermentation, (e) adding the flavour concentrate before, during or after step (c).
Patent NZ-531439-A (NZ)
Title: Method and apparatus for sample preparation using solid phase microextraction
Inventor: ABDEL-REHIM MOHAMED
IPC: G01N30/16
Filed: 2002-08-28
Abstract: A method and an apparatus for use in performing sample preparation of a liquid sample using solid phase microextraction. The method comprises the steps of: drawing a liquid sample comprising analytes into a syringe having a syringe barrel provided with a solid phase material; passing the liquid sample through the solid phase material such that the analytes are absorbed to the solid phase material; and eluting the analytes with a liquid solvent directly into the injector of an anlysing instrument. The apparatus comprises a syringe having a syringe barrel with a plunger slidable within the barrel and a hollow needle extending from the barrel. The liquid sample is drawn through the needle into the barrel wherein a solid phase material is provided in the syringe barrel to be contacted by the liquid sample drawn into the syringe.
Patent NZ-531754-A (NZ)
Title: Investment trading options having demand-based, adjustable returns, and trading exchange methods therefore
Inventor: LANGE JEFFREY
IPC: G06Q30/00
Filed: 2002-09-09
Abstract: Methods and systems for conducting demand-based trading are described. A plurality of states is established with each state corresponding to at least one possible outcome of an event of economic significance. An indication of a desired payout and an indication of a selected outcome are received. The selected outcome corresponds to at least one of the plurality of states. An investment amount as a function of the selected outcome, the desired payout and a total amount invested in the plurality of states is determined by a computer. Also disclosed is receiving indication of a desired payout for a financial product and determining by computer at least one of an investment amount, a limit on the investment amount of each contingent claim in a set of at least one contingent claim as a function of the desired payout. Also disclosed is receiving indication of a desired payout for a financial product and determining by computer an investment amount and a selection outcome for each contingent claim in a set of at least one contingent claim as a function of the desired payout and a total amount invested in a demand based auction.
Patent NZ-536456-A (NZ)
Title: Medium for contrast enhancement use for ultrasonic, endoscopic and other medical examinations
Inventor: DE ZIEGLER DOMINIQUE
IPC: A61B5/05
Filed: 2003-05-08
Abstract: Use, in the manufacture of a composition for use in a medical imaging procedure involving a body or organ cavity, of an image enhancing medium which comprises a polymer, copolymer or colloidal clay and which is formulated such that it: (a) is initially solid or viscous upon or after introduction to the body or organ cavity; and (b) then liquefies or decreases in viscosity after passage of sufficient time to conduct said medical imaging procedure, and is expelled or easily removed from the cavity.
Patent NZ-537490-A (NZ)
Title: Treatment of diabetes and syndrome X using a sulfamate derivate such as topiramate and metformin
Inventor: CONNOR GREGORY S
IPC: A61P3/10
Filed: 2001-10-25
Abstract: Disclosed is the use of topiramate and metformin in the preparation of a medicament for the treatment of Type II diabetes mellitus or Syndrome X. Also disclosed is a composition and pharmaceutical product comprising topiramate and metformin. (62) Divided Out of 525724
Patent NZ-542962-A (NZ)
Title: Indene derivatives as pharmaceutical agents
Inventor: RAYMOND JEFFERY R
IPC: C07D233/54
Filed: 2004-04-15
Abstract: Disclosed are compounds of formulae (I) and (II), wherein the substituents are as defined in the specification. The compounds are anti-inflammatory agents useful in the treatment of diseases such as asthma, chronic obstructive pulmonary disease, multiple sclerosis, psoriasis and inflammatory bowel disease.
Patent NZ-543709-A (NZ)
Title: Use of tyrosine kinase inhibitor to treat diabetes
Inventor: HAGERKVIST ROBERT PER
IPC: A61K31/47
Filed: 2004-05-26
Abstract: Disclosed is the use of 4-(4-methylpiperanzin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutically acceptable salt thereof for the manufacture of a medicament to treat or to prevent diabetes.
Patent NZ-544107-A (NZ)
Title: Product quality estimation method and system
Inventor: PLEASANTS ANTHONY BRYAN
Filed: 2006-01-12
Abstract: Computer executable instructions are configured to estimate the quality of a product at a set time. The instructions are configured to execute the steps of initially defining a model for the change in quality of a product over time, and then calculate at least one quality estimate distribution for the product at a set future time using the model. Next a recording is made of at least one corresponding quality measurement distribution at the set time involved and then a determination is made as to whether the model is valid or not based on differences between the estimated and measured distributions. If the model is deemed to be invalid then it is reconfigured using the received quality measurement distribution or distributions.