baber/WOPTO huggingface dataset:
Patent DE-69315993-T2 (DE)
Inventor: RAPPUOLI RINO
IPC: A61K39/385
Filed: 1993-03-08
Granted: 1998-07-02
Abstract: The present invention provides conjugate compounds comprising at least one heat shock protein or portion thereof including at least one immunostimulatory domain and at least one capsular oligosaccharide or polysaccharide of a pathogenic bacteria. The compound comprises oligosaccharides of the Meningococci C (MenC) group and a heat shock protein selected from M. bovis BCG GroE1-type 65 kDa hsp (hspR65), recombinant M. tuberculosis DnaK-type 70 kDa hsp (hspR70) and a heat shock protein from H. pylori. The invention also provides processes for producing conjugate compounds, pharmaceutical compositions comprising conjugate compounds, therapeutic compositions comprising conjugate compounds, and methods of inducing an immune response.
Patent DE-69406451-T2 (DE)
Inventor: BERNARD DIDIER
IPC: C07C317/28
Filed: 1994-07-13
Granted: 1998-02-26
Abstract: PCT No. PCT/FR94/00880 Sec. 371 Date Jan. 16, 1996 Sec. 102(e) Date Jan. 16, 1996 PCT Filed Jul. 13, 1994 PCT Pub. No. WO95/02576 PCT Pub. Date Jan. 26, 1995A process for the preparation of N-carbonylarylimine of the general formula I:    <IMAGE>  I  in which Ar represent an aryl radical and R represent a phenyl or t-butoxy radical, by desulphonating the compound of the general formula II.    <IMAGE>  II  The compounds of formula II are novel when R is t-butoxy.
Patent DE-69409259-T2 (DE)
Inventor: OSTINET ROBERTO
IPC: G02C5/22
Filed: 1994-12-19
Granted: 1998-09-10
Abstract: On the basis of this invention, a new type of connection and elastic hinge between spectacle ear pieces and the frame is provided. The substantial innovative feature of the invention is the production of a hinge between the ear piece (30) and the frame without a screw or hinge pin; it is composed of a bolt (10) with an enlarged head (11) found inside a bore (2) of a bush (1) incorporated in a frame element (13) which is connected to the front (14) of the spectacle frame allowing the rotation of the enlarged part (11) inside the bore (2) and consequently the rotation of a flat part (12) of the bolt (10) inside a slot (4) of the bush (1), whereby the enlarged part (11) is engaged to a plunger (20) which positions and guides an elastic device (22).
Patent DE-69412123-T2 (DE)
Inventor: CURRAN WILLIAM
IPC: D02G3/46
Filed: 1994-11-08
Granted: 1998-12-03
Abstract: A method for making a thread comprising: feeding at least two drawn, continuous filament starting threads (18, 19), of which at least one is a multi-filament thread, together to an intermingling device (21) to form a single bulked thread of which the filaments of the starting threads are intermingled and looped, and applying a bulk-reducing treatment to the bulked thread characterized in that the bulk-reducing treatment comprises a treatment under tension without the thread being heated.
Patent DE-69421294-T2 (DE)
Inventor: FROST PETER
IPC: G02B6/00
Filed: 1994-09-08
Granted: 2000-05-11
Abstract: A splice tray (4) has a main body portion (9) and a fibre entry/exit portion (10). The main body portion (9) holds at least one splice and stores fibres leading to the splice(s). The fibre entry/exit portion feeds fibre to/from the main body portion (9), and is formed with at least one fibre test zone (19a, 19b, 21a, 21b).
Patent DE-69427344-T2 (DE)
Inventor: BOUSSEAU ANNE
IPC: A61K31/425
Filed: 1994-02-25
Granted: 2002-04-25
Abstract: The invention relates to the application of riluzole or the pharmaceutically acceptable salts of this compound in the treatment of neuro-AIDS.
Patent DE-69430701-T2 (DE)
Inventor: SINNREICH JOEL
IPC: G01N13/00
Filed: 1994-07-28
Granted: 2002-11-07
Abstract: PCT No. PCT/EP94/02485 Sec. 371 Date Feb. 6, 1996 Sec. 102(e) Date Feb. 6, 1996 PCT Filed Jul. 28, 1994 PCT Pub. No. WO95/15329 PCT Pub. Date Jun. 8, 1995An apparatus for simulating the effect of a living organism on the change in shape, the disintegration and dissolution behaviour and the active-ingredient release of a pharmaceutical dosage form, including a beaker-shaped container for accommodating a test medium and the pharmaceutical dosage form and an agitating device for agitating the test medium, which agitating device can be moved periodically in a reciprocating movement into and back out of the container, wherein the agitating device includes a piston-shaped head portion arranged on a piston rod, which head portion is provided with through-openings for the test medium and the distance of the piston-shaped head portion from the container floor can be altered periodically in accordance with the periodic reciprocating movement of the agitating device, wherein, the piston rod is suspended from a gallows-shaped boom or the piston rod passes through a bore in the gallows-shaped boom in such a manner that downward movement of the piston-shaped head portion arranged on the piston rod is caused by gravity alone and wherein there is arranged in the container an intermediate base supported on the container floor, the base being provided with through-openings for the test medium and serving as a support for the dosage form, wherein the distance between the intermediate base and the container floor is adjustable by a device for adjusting the distance between the base and the floor.
Patent DE-69431835-T2 (DE)
Inventor: HASEL KARL W
IPC: A61P31/18
Filed: 1994-03-25
Granted: 2003-08-14
Abstract: The subject invention provides a recombinant nucleic acid molecule which encodes a mutant HIV-1 gp120 envelope glycoprotein comprising a V3 loop deletion and a C4 domain(W->X) point mutation wherein X is an amino acid residue other than tryptophan, and the HIV-1 gp120 envelope glycoprotein encoded thereby. The subject invention further provides a method of obtaining partially purified antibodies which specifically bind to the CD4-binding domain of HIV-1 gp120 envelope glycoprotein, the partially purified antibodies produced thereby, and pharmaceutical compositions comprising same. Finally, the subject invention provides methods of treating HIV-1-infected subjects, and of reducing the likelihood of HIV-1-exposed and non-HIV-1-exposed subjects' becoming infected with HIV-1 using the pharmaceutical compositions of the subject invention.
Patent DE-69511769-T2 (DE)
Inventor: KRAMER CAROLYN M
IPC: A61K6/00
Filed: 1995-06-02
Granted: 1999-12-23
Abstract: The kit comprises three powders, the first of which is enclosed by a first labelled container having a first opacity (O1) and a first lightness value (L1), when formed into an opaque porcelain layer. The second powder is enclosed by second labelled container having a second opacity (O2) and a second lightness value (L2), when formed into the less opaque ceramic layer. The third powder enclosed by a third labelled container has a third opacity (O3) and a third lightness value (L3), when formed into the most opaque ceramic layer. The third opacity is greater than the second opacity and the second opacity is greater than the first opacity. Also, the third lightness value is greater then the second lightness value and the second lightness value is greater then the first lightness value.
Patent DE-69532163-T2 (DE)
Inventor: ANGEL SHLOMO
IPC: G01G3/14
Filed: 1995-05-18
Granted: 2004-07-22
Abstract: The invention concerns a low-profile load cell comprising :  a. a flat metal plate having a generally uniform horizontal cross-section comprising :  (1) a load-receiving member (1) comprising a first transverse section (4) integral with a load-receiving tongue (5), the load-receiving tongue (5) arranged symmetrically about a north-south axis of the plate, extending across an east-west axis of the plate, and receiving the load to be measured over an area symmetrical about the north-south and east-west axes; (2) a clamping member (3) comprising a second transverse section (7) opposed from the first transverse section (4) across the east-west axis; and (3) two flexure beams (2) extending across the east-west axis and connecting the first and second transverse sections (4, 7) of the metal plate, a first half of each flexure beam (2) symmetrical to a second half about the east-west axis, and the flexure beams (2) symmetrical to each other about the north-south axis; and  b. a pair of strain transducers (8 & 10, 9 & 11) mounted on each flexure beam (2) with each transducer of each pair of transducers equi-distant from the east-west axis;  wherein, when a load is applied to the load-receiving element the flexure beams (2) each bend into a symmetrical double-cantilever S-shape, and each transducer in each transducer pair (8 & 10, 9 & 11) produces an electronic signal equal and opposite to the other transducer in the transducer pair. <IMAGE>
Patent DE-69533575-T2 (DE)
Inventor: BURKES THERESA A
IPC: G06F12/16
Filed: 1995-07-11
Granted: 2006-01-05
Abstract: A hierarchic disk array data storage system (10) has multiple storage disks (12) that define a physical storage space (34) and a RAID management system (16) that maps the physical storage space into two virtual storage spaces (40, 50). The RAID-level virtual storage space (40) presents the physical storage space (34) as mirror and parity RAID areas where the mirror RAID areas contain mirror allocation blocks to store data according to RAID Level 1 and the parity RAID areas contain parity allocation blocks to store data according to RAID Level 5. The application-level virtual storage space (50) presents the physical storage space (34) as multiple virtual blocks. The RAID management system (16) migrates data between the mirror and parity RAID areas to optimize performance and reliability. To ensure that sufficient space is retained for this migration, the RAID management system (16) limits the number of virtual blocks that are allocated in the mirror RAID areas. The maximum number of virtual blocks in mirror RAID areas is dynamically computed based upon a function of the physical capacity of the storage disks, the number of storage disks, and the allocated capacity at the time of each storage request from the user. <IMAGE>
Patent DE-69533665-T2 (DE)
Inventor: TIEDEMANN G
IPC: H04L1/12
Filed: 1995-07-05
Granted: 2006-02-16
Abstract: A method and apparatus for controlling transmission power in a variable rate communication system is disclosed. The method disclosed provides for a closed loop power control method. A first remote station controls the transmission power of a second remote station by transmitting a rate dependent power control signal to the second remote communication station. Since only the second communication knows its transmission rate a priori, it must determine its course of action in accordance with both the received power control signal and the knowledge of its transmission rate.
Patent DE-69535541-T2 (DE)
Inventor: AURIK ERIK ARNOLDUS
IPC: A01J5/017
Filed: 1995-02-17
Granted: 2008-04-17
Abstract: A cleaning device for cleaning a teat of an animal, the cleaning device (25) comprising:     a feed conduit (29) for supplying a cleaning medium; a housing (26) having an open top side (27) for receiving the teat and an open bottom side for draining the cleaning medium admitted into the housing via the feed conduit (29); and at least one outlet opening for the cleaning medium arranged in the housing (26) and in flow communication with the feed conduit (29), so obtaining an optimal cleaning treatment and in particular by means of an automatically operated milking arm.   <IMAGE>
Patent DE-69608311-T2 (DE)
Inventor: PARL A
IPC: G01S1/04
Filed: 1996-12-09
Granted: 2000-09-14
Abstract: A position location system includes multiple base stations spaced over a region. A remote unit within the region transmits a locating signal which is received by the base stations. The base stations report amplitude, phase and time data related to the locating signal to a control station. The control station includes a processor and memory that combine the data from all of the participating base stations to directly compute an optimal estimate of the location of the portable unit. The control station generates a locator function based upon the probability that the portable unit is located at a particular position. By optimizing the locator function, the error in the computation is minimized to produce an accurate position estimate.
Patent DE-69608913-T2 (DE)
Inventor: BORCHARDT KEITH
IPC: D21C5/02
Filed: 1996-10-09
Granted: 2000-11-02
Abstract: This invention related to a process for the deinking of office wastepaper stocks which comprises: a) converting the wastepaper to a pulp, b) contacting the pulp with an aqueous medium of alkaline pH containing between 0.05 and 2 percent by weight, calculated on a dry weight basis of the pulp, of a deinking agent comprising a first component comprising at least one ethylene oxide adduct of a detergent-range alcohol having in the range of from 8 to 20 carbon atoms and an average of from 3 to 20 oxyethylene units per molecule of alcohol, a second component selected from the group consisting of one or more detergent-range olefins having from 8 to 22 carbon atoms, one or more saturated hydrocarbons having from 8 to 20 carbon atoms, and mixtures thereof and optionally a third component comprising a detergent-range alcohol having from 8 to 20 carbon atoms, and c) treating the resulting pulp-containing medium by washing or flotation to remove suspended ink therefrom.
Patent DE-69612000-T2 (DE)
Inventor: ENGDAHL BJOERN
IPC: F16L37/12
Filed: 1996-06-28
Granted: 2001-11-08
Abstract: PCT No. PCT/SE96/00860 Sec. 371 Date Jan. 13, 1998 Sec. 102(e) Date Jan. 13, 1998 PCT Filed Jun. 28, 1996 PCT Pub. No. WO97/04267 PCT Pub. Date Feb. 6, 1997A hose coupling incorporates a male part and a female part that is provided with a mechanism, which in cooperation with a slide axially displaceable on the female part renders possible pressure relief at disconnection. One of the mechanisms in the coupling is an angular locking body including a portion that is insertable in an axial groove in the female part, and has a length, such that the angular locking body is always at least substantially surrounded by a sleeve. The other inwardly directed part of the locking body has a length, such that the part extends into the groove of the male part when the locking body is influenced by the sleeve.
Patent DE-69614179-T2 (DE)
Inventor: ANDERSON CHARLES H
IPC: G02B27/00
Filed: 1996-04-26
Granted: 2002-04-18
Abstract: Variations on the Koehler illumination system, used for providing light to be reflected from, or transmitted by, an SLM (16). An anamorphic illumination system (10) uses multiple light sources (11) and a cylindrical lens (14) to provide an elongated and compressed beam to the SLM (16). A cascaded illumination system (30) uses multiple light sources (31) and multiple TIR prisms (33) to provide an extended light beam or one that is more intense, to the SLM (36). <IMAGE>
Patent DE-69616936-T2 (DE)
Inventor: PATELL MAHESH
IPC: A61K9/28
Filed: 1996-07-26
Granted: 2002-07-18
Abstract: Gelatin coated pharmaceutical dosage units containing, for example, analgesic compounds, such as aspirin, stabilized with a proteolytic enzyme, such as pepsin, are described.
Patent DE-69622053-T2 (DE)
Inventor: SJOEBERG MICHAEL
IPC: B29C48/94
Filed: 1996-09-20
Granted: 2002-11-14
Abstract: PCT No. PCT/SE96/01169 Sec. 371 Date Mar. 20, 1998 Sec. 102(e) Date Mar. 20, 1998 PCT Filed Sep. 20, 1996 PCT Pub. No. WO97/10936 PCT Pub. Date Mar. 27, 1997The invention relates to a process for heating polymer material, including irradiation of said polymer material with infrared radiation. In accordance with the process according to the invention the infrared radiation has wave lengths which substantially are not equal to the absorption peaks of the polymer material in respect of infrared radiation.
Patent DE-69628173-T2 (DE)
Inventor: DEREVYAGIN ALEXANDR MIKHAILOVI
IPC: G01N25/68
Filed: 1996-07-16
Granted: 2004-03-25
Abstract: The proposed method of determining dew point involves directing the gas under investigation onto a cooled section of an optically transparent body through which a luminous flux is allowed to pass and recording fluctuations in the intensity of the luminous flux, the flow-rate of the gas thus directed onto the cooled section being reduced down to zero while its molecular diffusion is preserved. To limit the flow-rate of the gas impinging on the cooled section (1) and reduce contamination of the optically transparent element, the dew point gauge is provided with a sampling tube (10). <IMAGE>
Patent DE-69700436-T2 (DE)
Inventor: LOUE WILLEM
IPC: C22C21/04
Filed: 1997-03-12
Granted: 2000-02-03
Abstract: The invention relates to an aluminum alloy for thixoforming with the composition (by weight): Si: 5%-7.2% Cu: 1%-5% Mg<1% Zn<3% Fe<1.5% other elements<1% each and<3% in total, with % Si<7.5-% Cu/3, which, when reheated to the semisolid state to the point at which a liquid fraction ratio between 35 and 55% is obtained, has an absence of non-remelted polyhedral silicon crystals.
Patent DE-69704281-T2 (DE)
Inventor: TAIT PETER DONALD FRASER
IPC: G01S7/02
Filed: 1997-09-18
Granted: 2001-07-12
Abstract: A coherent radar detection system (2) comprises a radar signal transmitter (4) and a correlation receiver (6). The transmitter (4) comprises a waveform generator which generates a signal at an intermediate frequency. The signal is divided into two divided signals by a coupler, and then the divided signals are mixed together in a mixer to generate an output signal which has a wider bandwidth than the intermediate frequency. The bandwidth can be increased further by repeating the coupler/mixer stage. The system generates very wide bandwidth signals coherently, allowing coherent processing in high resolution range gates.
Patent DE-69706556-T2 (DE)
Inventor: HORSTMAN LAWRENCE
IPC: A61K8/02
Filed: 1997-10-23
Granted: 2002-04-25
Abstract: A unidirectional twist-up dispensing device with incremental dosing for dispensing a product is provided. This twist-up dispensing device includes a hollow housing defining a chamber having an open dispensing end and an open actuating end having a interior surface. A piston located within the chamber being limited to translational movement within the chamber. The piston having a top side facing the dispensing end of the housing forming a variable volume portion of the chamber for storing the product. The piston also having a threaded rod extending therefrom opposite the top side. An actuator having a threaded aperture therethrough that engages the interior surface at the actuating end of the housing is also provided. The threaded aperture is concentric in the actuator and the actuator is adapted to rotate with respect to the housing in only one direction. The threaded rod engages the threaded aperture such that advancement of the piston toward the dispensing end occurs when the actuator is rotated, thereby causing the product to be dispensed. An applicator can be attached to the dispensing end of the housing in fluid communication with the variable volume portion of the chamber wherein the product is dispensed through the applicator. The applicator comprises a ferrule and an application portion. The ferrule is attached to the dispensing end of the housing and the application portion has at least one orifice located therein. Several versions of the applicator are illustrated, including a fiber brush and a flocked application surface.
Patent DE-69712474-T2 (DE)
Inventor: GRINTER JOHN
IPC: C07F9/40
Filed: 1997-02-21
Granted: 2003-01-16
Abstract: PCT No. PCT/GB97/00481 Sec. 371 Date Aug. 20, 1998 Sec. 102(e) Date Aug. 20, 1998 PCT Filed Feb. 21, 1997 PCT Pub. No. WO97/31004 PCT Pub. Date Aug. 28, 1997A process for the preparation of a compound of formula I, wherein R1 and R2 are independently C1-6 alkyl, R3 is hydroxy and R4 and R5 are independently C1-6 alkyl is disclosed. The process comprises reacting a compound of formula II, wherein R1, R2 and R3 are defined as in formula I and X is a leaving group, with a compound of formula III, wherein R4 and R5 are independently C1-6 alkyl, in the presence of a base.
Patent DE-69717862-T2 (DE)
Inventor: TAPOLSKY GILLES H
IPC: A61K9/22
Filed: 1997-10-16
Granted: 2003-05-08
Abstract: The present invention relates to a pharmaceutical delivery device for application of a pharmaceutical to mucosal surfaces. The device comprises an adhesive layer and a non-adhesive backing layer, and the pharmaceutical may be provided in either or both layers. Upon application, the device adheres to the mucosal surface, providing localized drug delivery and protection to the treatment site. The kinetics of erodability are easily adjusted by varying the number of layers and/or the components.
Patent DE-69725573-T2 (DE)
Inventor: JAEKAERAE JUKKA
IPC: C07C217/08
Filed: 1997-05-30
Granted: 2004-08-19
Abstract: A process for the bleaching of chemical pulp, in which process the pulp is delignified with a peracid and additionally the pulp is chelated in order to bind heavy metals, such as Fe, Mn and/or Cu, into a chelate complex. According to the invention, the chelating is carried out using a chemical which has been selected from a group consisting of N-bis-((1,2-dicarboxy-ethoxy)-ethyl)-amine, N-bis-((1,2-dicarboxy-ethoxy)-ethyl)-aspartic acid and N-tris-((1,2-dicarboxy-ethoxy)-ethyl)-amine, as well as the alkali metal and earth-alkali metal salts thereof, and the peracid and chelating treatments are carried out simultaneously by combining the peracid and the said chelating chemical in the same solution phase. In the bleaching sequence the treatment according to the invention may follow, for example, an ozone delignification and precede an alkaline peroxide step, and in the latter case a magnesium compound, such as MgSO4, may be added to the pulp before the alkali step.
Patent DE-69811081-T2 (DE)
Inventor: RANZONI FRANCESCO
IPC: A47J45/06
Filed: 1998-07-15
Granted: 2004-01-22
Abstract: A kitchen utensil (400) has a receptacle (405) and at least one handle (420) connected to the receptacle (405), a predominant portion of the handle (420) being divided along a substantially longitudinal direction (A) into a first portion (425) and a second portion (430) which fit together at least partially along the longitudinal direction (A) and each of which is articulated to the receptacle (405) for pivoting between a rest position in which it is disposed with a free end in the vicinity of the receptacle (405) thus reducing the bulk of the utensil, and a working position in which the first portion and the second portion (425, 430) are joined together so that the handle (420) forms a substantially unitary element firmly fixed to the receptacle (405) for firm gripping of the utensil.
Patent DE-69813549-T2 (DE)
Inventor: KING MALCOLM
IPC: A61K31/721
Filed: 1998-06-30
Granted: 2004-02-26
Abstract: This invention relates to the use of polysaccharide such as dextran to improve mucus clearance. In the present invention, dextran has been shown to reduce viscoelasticity and increase mucus clearability of sputum of cystic fibrosis patients. Dextran also reduces viscoelasticity of healthy dog mucus. The present invention therefore may be used to improve mucus clearance in cystic fibrosis patients and treat other conditions associated with defect in ariway mucus clearance including chronic bronchitis, bronchiectasis and bronchial asthma.