baber/WOPTO huggingface dataset:
Patent CR-20200612-A (CR)
Title: Glp-1 receptor agonists and uses thereof
Inventor: LIAN YAJING
IPC: C07D413/14
Filed: 2019-06-11
Abstract: <p>Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza- 5-aza-, and 7-aza-benzimidazoles as GLP-1 R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof (Formula I).</p>
Patent CR-20210360-A (CR)
Title: A frame for an electric vehicle
Inventor: CHAUDHARI JAYESH SHARAD
IPC: B60K1/04
Filed: 2019-12-11
Abstract: A frame for an electric vehicle (10) comprising: a head pipe (12) and at least two rear tubes (13) extending rearwardly from the head pipe (12); an electric battery module (24) used as a power source for powering the electric vehicle comprising at least one battery located below rear portion (13B) of said rear tubes (13); a protective frame structure (23) for securely mounting said battery module (24); wherein said protective frame structure (23) is fixed to said rear tubes (13) of said frame and provided substantially centrally and downwardly of said vehicle (10).
Patent CR-20220065-A (CR)
Title: Method for the characterization of peptide:mhc binding polypeptides
Inventor: SCHUSTER HEIKO
IPC: G01N33/569
Filed: 2020-08-12
Abstract: The present invention relates to a method for the characterization of peptide: MHC binding polypeptides, e.g. by mass spectrometry and an analysis of the recognized peptide space, i.e. in order to identify peptides that can be bound in the context of their presentation by MHC, and those who can not be bound.
Patent EC-SP066969-A (EC)
Title: Atomizador para la distribución de líquidos para fines médicos
Inventor: JUNG ANDREE
IPC: A61M11/00
Filed: 2006-11-01
Abstract: Se describe un atomizador para fines médicos para la distribución de líquidos desde al menos un cartucho insertable en el atomizador así como un cartucho y un sistema, que está constituido por un atomizador y un cartucho insertable en el mismo.Tales atomizadores (1) se necesitan, por ejemplo, para la aplicación de formulaciones de medicamentos líquidos activos por inhalación y comprenden, como módulos esenciales, un porta-cartuchos (4) dispuesto en la carcasa (3), una boquilla (5) configurada en la carcasa (3), en la que está dispuesto un dispositivo de atomización (6), y un sistema de tubo de unión (7), que conecta el dispositivo de atomización (6) y el porta-cartuchos (4), en el que el dispositivo de atomización (6) presenta al menos un cuerpo de toberas (8) y el sistema de tubo de unión (7) presenta al menos un canal (9) con un pistón hueco (10) alojado de forma desplazable en el mismo, en el que el pistón hueco (10) comprende un cuerpo de válvula (21).De acuerdo con una primera forma de realización, el atomizador (1) presenta un primer pistón hueco (10a), alojado desplazable en un primer canal (9a), y un segundo pistón hueco (10b), alojado desplazable en un segundo canal (9b), en el que el primer pistón hueco (10a) y el segundo pistón hueco (10b) se extienden hasta el interior del porta-cartuchos (4).
Patent EC-SP972340-A (EC)
Title: Nuevos compuestos
Inventor: KING FRANCIS DAVID
IPC: A61K31/00
Filed: 1997-12-16
Abstract: Nuevos derivados de uslfonamida con actividad sobre el SNC, procedimientos para su preparación y su utilización como medicamentos.
Patent GB-1047336-A (GB)
IPC: F23D11/00
Abstract: 1,047,336. Burners. VAPOR CORPORATION. Aug. 1, 1963 [May 6, 1963], No. 30512/63. Heading F4T. A burner assembly for mounting in the combustion throat 20 of a steam generator comprises a gas nozzle, Fig. 4 (not shown), or an oil nozzle 27 surrounded by a cylindrical air register 31 and an apertured stabilizing cone 37 arranged between the nozzle and the combustion throat. The air register is mounted in an annular plenum chamber 17 supplied with air by a blower and comprises a plurality of openings, each having a louvre which extends inwardly and at an angle to a radius of the register. A further air inlet passage 34 is provided between the outlet end of the stabilizing cone 37 and the throat 20. A pilot lighting device (not shown) is provided. The gas nozzle, Fig. 4 (not shown), has a flame spreader which may be conical. The combustion throat 20 leads to a refractory lined cylindrical fire pot having a flared choke at its outlet to a steam generator having water tubes, a water pump and a drum in which steam and water are separated.
Patent GB-1053573-A (GB)
IPC: C07J5/00
Abstract: 1,053,573. 6-Keto-pregnanes. AYERST McKENNA & HARRISON Ltd. June 2, 1964 [June 4, 1963], No. 22819/64. Heading C2U. The invention comprises compounds of formula wherein R is a hydrogen atom or an acyloxy or C 1-4  straight-chain alkyl group, R<SP>1</SP> is a hydrogen atom or an acyl group and X is a hydrogen or fluorine atom, and their preparation from a compound of formula by (a) reaction with an epoxidizing agent to form the corresponding 5,6-oxido-pregnane, converting this to the corresponding 5,α- hydroxy-6-keto-pregnane either directly by treatment with chromic acid, or by reaction with a perhalo-acid to form a 5α,6#-dihydroxy-pregnane followed by treatment of this with chromic acid, and dehydrating the 5α-hydroxy-6-ketopregnane by thionyl chloride, (b) treatment with formic acid and hydrogen peroxide to form a 5α - hydroxy - 6# - -formyloxypregnane, hydrolysis of this to a 3#,5α,6#-trihydroxy-pregnane, oxidation by N-bromo-succimide to a 3#,5α-dihydroxy-6-keto-pregnane, 3-acylation, and dehydration as in (a), or (c) reaction with hypochlorous or hypobromous acid to form a 5α- halo-6#-hydroxy-pregnane, oxidation with chromic acid to form a 5α-halo-6-keto-pregnane, and dehydrohalogenation by an organic base. Compounds of formula are prepared by reaction of a compound of the invention with phosphorus pentachloride to form a 6-haio-pregna-4,6-diene, followed by 3-hydrolysis and oxidation.
Patent GB-1225285-A (GB)
IPC: H01B13/00
Filed: 1968-05-23
Abstract: 1,225,285. Heat-treating copper alloys. OLIN CORP. May 23, 1968 [June 26, 1967], No.47548/69. Divided out of 1, 225, 282. Heading C7A. A copper-base alloy containing in percentage by weight is held at 800‹ to 1050‹C. for at least 10 minutes, and is then cooled to a temperature in the range 400‹ to 550‹C. at which it is held for at least 30 minutes.
Patent GB-1229269-A (GB)
IPC: C08B1/06
Filed: 1968-10-10
Abstract: 1,229,269. Treating wood pulp. EASTMAN KODAK CO. 10 Oct., 1968 [2 Feb., 1968], No. 48128/68. Heading D2W. The lignin in an unbleached sulphite pulp is rendered at least 1% by wt soluble in 5% by wt NaOH and the pulp is then treated with a solution of 8% by wt NaOH or the equivalent amount of another alkali metal hydroxide, and at least 1% by wt of M 2 B 4 O 7  (M is an alkali metal) or at least the amount of an alkali metal borate, perborate or metaborate equivalent, in terms of B content, to 1% by wt Na 2 B 4 O 7 , at at least 60‹C for at least 15 mins; the pulp is then filtered, washed and bleached. The lignin may be solubilised by treatment with chlorine water. The bleaching step may use a solution of ClO 2  followed by a treatment with HCl soln.
Patent GB-1231663-A (GB)
IPC: G01M9/04
Filed: 1968-05-31
Abstract: 1,231,663. Mountings for helicopter rotors. UNITED AIRCRAFT CORP. 31 May, 1968 [5 June, 1967], No. 54715/70. Divided out of 1,231,662. Heading B7N. [Also in Division F2] A rotary body is so connected to a support that torque about a predetermined axis is transmitted between the body and the support, but vibrations of the body about other axes are isolated from the support. The means employed may be substantially the same as in Specification 1,231,662. In Fig. 1, the rotary body is a helicopter rotor 154 and transmission 156 which is mounted on a fuselage 158 on four pairs of pivotally interconnected rods such as 170, 186, each pair being associated with a damper such as 160 of the same form as the dampers 38 of Specification 1,231,662. The arrangement is such that the rotor torque is transmitted to the foundation 158 but the rotor thrust T and rocking moments M are damped out. An alternative rotor mounting (Fig. 3, not shown) employs taut flexible straps in place of the pivotally interconnected rods of Fig. 1.
Patent GB-1231772-A (GB)
IPC: B27D5/00
Filed: 1969-03-25
Abstract: 1,231,772. Veneering. HELMES MACHINEFABRIEK N.V. 25 March, 1969 [2 April, 1968], No. 15515/69. Heading B5L. A method for gluing a strip 12 of material on the side of a flat workpiece 17, such as a table leaf, comprises rotating the workpiece in its own plane by engagement of a drive 2, 3 with the circumference of a guide 15, 16 having substantially the same form as the workpiece and connected thereto, simultaneously feeding the adhesive strip to the edge of the workpiece, and pressing the strip against the edge by means of a resiliently urged roller 7. In apparatus for carrying out the method, a drive roller 2 projects upwardly from a table 1 and engages one side of a ridge 16 formed on the guide 15, the other side of the ridge being engaged by a roller 3 which is mounted on an arm 5 urged about a pivot 10 by a pneumatic device 6. The guide is supported for movement over the table 1 by rollers 21 and an adjustable roller 22. The workpiece 17 rests on non-skid pads 18 on the guide and is pressed against the pads by an adjustable roller 19. The strip 12 in the form of veneer is fed by a roller 14 from a container 13 past a roller 11 which may apply glue from a heated tank to the strip or is heated to soften glue already on the strip, the strip then being pressed against the side of the workpieee by a roller 7 on an arm 8 urged about the pivot 10 by a pneumatic device 8.
Patent GB-1232320-A (GB)
IPC: A01D34/66
Filed: 1969-12-18
Abstract: 1,232,320. Mowers. V. POSSAMAI and M. POSSAMAI [trading as ALPINA DI POSSAMAI VITTORIO & MARIO S.I.N.C.]. 18 Dec., 1969 [31 Dec., 1968], No. 61810/69. Heading A1F. A mowing device has blades 3 rotating in a horizontal plane on a disc 4 mounted at the lower end of a vertical axle 7. The blades 3 cut vegetation between the teeth of a fixed serrate-edged plate 8. The axle 7 also carries triangular spikes 5 which rotate above the level of the blades 3. The spikes and blades protrude from the chassis 1 through slits. Vegetation cut by the blades 3 as the device is moved forward on a slide 2 is thrown by the spikes 5 into an ejection channel between the chassis 1 and a shield 9. The device may be driven by a belt 6 and two or more of the devices may be coupled together and the ejection channel may be formed between two counter rotating devices by the chassis 1.
Patent GB-1233817-A (GB)
IPC: E05F15/56
Filed: 1969-06-26
Abstract: 1,233,817. Hermetically sealed doors. COMMISSARIAT A L'ENERGIE ATOMIQUE 26 June, 1969 [3 July, 1968], No. 32340/69. Heading E1J. A hermetically sealed door, e.g. for use in closing closures containing dangerous products such as radioactive materials comprises a leaf 4 carrying by means of a transverse member 19 a cam-like slot 17 which cooperates with a pin 18 rigidly secured to the end of a reciprocable rod 14 in a casing 13 secured to the wall, the slot having two adjacent parts of which the part 17B is parallel to the plane of the leaf and the adjacent part inclined to the part 17B so that movement of the pin in the slot in the closing direction of the actuator causes rollers 9, 10 running in rebates 7, 8 such that the leaf is opposite the aperture and enables the actuator to press the leaf against a tubular gasket 23, 27, 28 on the aperture 3 surround frame which carries gasket-centring and locking pins (Fig. 4 and 5 not shown). The gasket is attached to the frame by cover strips, in two like pieces so that the door can be folded into two and passed through the aperture.
Patent GB-1239033-A (GB)
IPC: C07D277/76
Filed: 1968-10-07
Abstract: 1,239,033. Isothiocyanates. PHILIPS GLOEILAMPENFABRIEKEN N.V. 7 Oct., 1968 [10 Oct., 1967], No. 47453/68. Heading C2C. [Also in Divisions A5-A6] Compounds of the general formula in which R is alkyl, a benzyl group that bears one or more halogen atoms in the aromatic ring, or a 5- or 6 membered heterocyclic radical whose nucleus has aromatic characteristics and contains from one to three nitrogen and/or sulphur atoms as the hetero atom(s), and n is one or two, may be prepared by controlled oxidation of a compound of the formula R.S.CH 2 SCN, preferably using a per-acid, particularly m-chloroperbenzoic acid. Specified products include those in which R represents 2,4,5-trichlorobenzyl-, 2-benzthiazolyl-, 2-thienyl - 2 - pyridyl-, 6 - chloro - 3 - pyridazinyl-, 3 - phenyl - 5 - (1,2,4 - thiadiazolyl)-, 2 - methyl- 5 - (1,3,4 - thiadiazolyl)-, n - pentyl-, n - octyl-, and n-decyl. The compounds are useful as fungicides. Sulphides of the formula RSCH 2 SCN are prepared by reacting a mercaptan RSH with HCHO and a hydrohalic acid or SOCl 2  followed by treatment of the resulting halomethyl sulphide with a metal isothiocyanate, or by reacting a mercaptan R.SH with ClCH 2 SCN.
Patent GB-1239450-A (GB)
IPC: F16F15/121
Filed: 1968-06-28
Abstract: 1,239,450. Vibration dampers. HOLSET ENG. CO. Ltd. 28 June, 1968 [29 June, 1967], No. 30855/68. Heading F2S. A vibration damper consists of a housing containing an inertia weight connected by resilient spokes to a hub portion of the housing, its movement within the housing being damped by a viscous, e.g. liquid, medium filling the spaces between the weight and the adjacent housing surfaces. The spokes interconnect radially spaced parts of the hub and the weight, but are not integral with either. As shown in Fig. 1 the housing defines an annular chamber 17 of which the inner peripheral wall 14 has a portion 27 serving as a hub to which are attached a set of resilient metal or plastics discs 28 each of which has the form shown in Fig. 2. The inner ring of holes 24 in each disc receive screws 25, Fig. 1, for attaching the discs to the hub and the outer ring of holes 29 receive rivets 30 by which the set of discs is attached to the inertia weight 31. The housing contains more than enough damping liquid (e.g. silicone) to fill the spaces between the weight and the facing walls of the housing, the excess liquid being accommodated in a reservoir constituted by the slots 33 in the disc. The disc material between the slots provides a set of involute spokes 32. The complete assembly is designed to be secured to a rotary member such as a shaft 11 to damp torsional vibrations thereof. Fig. 3 (not shown) depicts a spring plate substitutable for the plate 28 of Fig. 2 but having radial instead of involute slots. Figs. 4 to 6 (not shown) depict constructions in which the spokes are separate resilient members fitted in grooves in both a hub and a surrounding annular weight. In Figs. 10 (not shown) and 11, the construction is generally similar to that of Figs. 4 to 6, but the separate resilient members are replaced by a helical coil fitted as shown in slots 214 and 215 in the hub 205 and annular weight 212 respectively. Other modified forms are depicted in Figs. 7 to 9, 12 and 13 (not shown).
Patent GB-1250208-A (GB)
IPC: A61K49/04
Filed: 1968-12-30
Abstract: 1,250,208. Radiopaque compositions. PHARMACIA A.B. 30 Dec., 1968 [28 Dec., 1967], No. 61601/68. Heading A5B. [Also in Division C2] Preparations for X-ray visualisation of body cavities comprise at least one acylamino-triiodobenzoic acid compound of the formula I where R 1  and R 1 ', are each H or C 1-5  alkyl and R 2 , R 2 ', R 3  and R 3 ' are each acyl of up to 5 carbons, A is C 3-20  alkylene substituted by one or more substituents -OR 4 , R 4  being H or alkyl or acyl of no more than 5 carbon atoms, the alkylene being optionally broken by one or more oxygen bridges, or physiologically acceptable salts thereof, in admixture with an inactive therapeutically acceptable carrier. The preparations may be in forms suitable for oral, parenteral or rectal administration.
Patent GB-1250287-A (GB)
IPC: G01N3/12
Filed: 1970-02-13
Abstract: 1,250,287. Pressure testing containers. WERNER & PFLEIDERER. Feb. 13, 1970 [March 22, 1969], No.7086/70. Heading G1S. A method of and apparatus for pressure liquid testing a container 11 employs, a hydraulic pump 2 and non-return check valve 4 supplying water to supply pipe 6 and a hydraulic accumulator 1, an air compressor 3 supplying air at maximum test pressure to cylinder 9 and water tube level gauge 7 and air at minimum test pressure to cylinder 10 and water tube level gauge 8, and sets of electrical contact switches 15-19 in each gauge tube operating test water supply and exhaust valves to the container 11. The compressed air acts as a reserve force in the system since liquids are not compressible, otherwise the liquid pressure in the container 1 and water level tubes 7 and 8 would drop to zero upon the slightest withdrawal or loss of fluid. The compressed air reservoirs of the containers 1, 9 and 10 are connected by a ring main to the compressor 3. In operation, when a stop valve 21 is opened, water already in 11 is subjected to the maximum water pressure in the gauge 7. This causes a float (not shown) to sink in the gauge 7 and operate switches 17, 16 which open valves 22, 23 and provide a direct supply connection to the accumulator 1. The pressure is thus raised again in the container 11 and gauge 7 and the float rises to shut supply valves 22, 23, and maintain the pressure within a limited range. When the period for testing at maximum pressure is completed the valve 21 is closed and this automatically opens valve 25 to connect the minimum pressure gauge 8 to the container so that a further but lower pressure test may be carried out on 11. Similar float operated switches 15<SP>1</SP>-19<SP>1</SP> are operated in gauge 8 to maintain the lower pressure also within a desired range. Contacts 15 and 19 in each gauge prevent compressed air from escaping or the water level from rising too far, and in the event of the maximum pressure being exceeded a contact 18 opens the exhaust valve 24.
Patent GB-1250463-A (GB)
IPC: G07D9/06
Filed: 1968-10-25
Abstract: 1,250,463. Coin packaging. KOKUEI KIKAI SEISAKUSHO K.K. 25 Oct., 1968 [11 Nov., 1967], No. 50804/68. Heading B8C. [Also in Divisions G4-G6] A coin receiving and stacking tube for use with a coin packaging machine, comprises a synthetic resin tube 1 having a corrosion and abrasion resistant sheet metal lining 4. The lower end of the tube is obturated by a horizontally or vertically movable support member (not shown) and coins of a particular denomination dropped into a hopper 2 are automatically oriented for stacking on the support member prior to removal and packaging. The lining 4 is stainless steel adhesively bonded to the tube 1 and may be provided with a longitudinal gap to allow for thermal expansion.
Patent GB-1250521-A (GB)
IPC: A47B95/04
Filed: 1968-02-16
Abstract: 1,250,521. Fluid-pressure operated motors. TRICO-FOLBERTH Ltd. May 15, 1969 [Feb. 16, 1968], No. 7786/68. Headings F1A, F1M and F1S. A fluid-pressure operated motor has a motor chamber 1 and a motor member 2 movable to and fro by fluid-pressure difference and pilot valve means 25 responsive to the movement of the member to operate a main valve 26 by fluidpressure difference and thereby reverse the member at the end of each stroke. There are first and second connections in parallel between the main valve and a source of fluid-pressure, the first connection passing through a restriction 60 and the second passing through the pilot valve means 25 which is arranged to close the second connection as the motor member approaches the end of each stroke and to reopen the second connection at the beginning of the next stroke. Divisional Specification 1, 250, 522 is referred to.
Patent GB-1250925-A (GB)
IPC: B21B1/22
Filed: 1969-07-02
Abstract: 1,250,925. Rolling. NIPPON KOKAN K.K., and TOKYO SHIBAURA ELECTRIC CO. Ltd. 2 July, 1969 [3 July, 1968], No. 33447/69. Heading B3M. [Also in Division G3] In a method and apparatus for rolling strip, detectors spaced across the width of a strip detect unevenness of the strip by detecting the amplitude of vibration of the strip in the direction of the strip thickness and the roll crown and rolling load of the mill are automatically controlled in response to the detected amplitudes. The apparatus comprises rolls 2 and backup rolls 3. Detectors 6A, 6B, 6C produce signals A, B and C which are transmitted via synchronous rectifier circuits 7A, 7B, 7C to amplitude circuits 8A, 8B, 8C, where a D.C. signal is passed to circuits 9, 10 and 11. Circuit 11 produces an output y=A-C which controls the total rolling load exerted by screw-downs 14, 14<SP>1</SP> and circuit 10 produces a signal x=A-B which controls the means 13, 13<SP>1</SP> which alter the roll crown. Circuit 9 is a discriminating circuit which delays operation of circuit 10 while circuit 11 is operating to balance the total rolling load.
Patent GB-1257536-A (GB)
IPC: B29C67/24
Filed: 1969-12-09
Abstract: 1,257,536. Melamine resin bonded stone particles. MEDIL S.p.A. 9 Dec., 1969 [10 Dec., 1968], No. 60016/69. Heading C3R. [Also in Division C1] Stone particles, e.g. limestone, are bonded with a thermosetting melamine resin.
Patent GB-1266341-A (GB)
IPC: G01N15/08
Filed: 1968-03-07
Abstract: 1,266,341. Measuring permeability of sheet material. E. S. & A. ROBINSON (HOLDINGS) Ltd. May 22, 1969 [March 7, 1968], No. 11267/68. Heading G1S. A sample of sheet material to be tested is placed between upper and lower halves A and B of a cell 2, which halves are then clamped together and are each provided with a scroll shaped channel separated by the sheet, the upper scroll being connected to a stream of test gas and the lower scroll being connected to a stream of carrier gas. In Fig. 2 the lower half B is connected to a source of carrier or helium gas 17 via control valves and a flowmeter 22, and the upper half A is connected to a source of test or nitrogen gas 33 via control valves and a flowmeter 36. In operation, the half B is first purged by carrier gas and then the purging valve 28 is turned off. The valves 18 and 32 are then turned on to flow both gases through their respective halves, so that any transmission of test gas through the sheet material may be detected by passing the low-pressure carrier gas with its traces of test gas out through a crunched capillary impedance conduit 31 to a spectrometer (not shown).
Patent GB-1288426-A (GB)
IPC: A23K20/195
Filed: 1969-12-24
Abstract: 1288426 Animal feeds containing kasugamycin BISEIBUTZU KAGAKU KENKYUKAI FOUNDATION 24 Dec 1969 62768/69 Heading A5B [Also in Division C2] Animal feeds for cattle, swine, poultry, trout and eels in particular comprise the antibiotic Kasugamycin together with animal foodstuff. The animal feed may be prepared by (i) cultivating in an aqueous nutrient medium comprising a carbon source, a nitrogen source and an inorganic salt, a strain of Streptomyces kasugaensis, which is capable of producing Kasugamycin; (ii) separating Kasugamycin from the resulting culture broth; (iii) mixing the crude Kasugamycin with an animal feed; and (iv) drying the mixture. The animal feed may also contain vitamins A, B and B complex, trace minerals and a coccidiostat.