baber/WOPTO huggingface dataset:
Patent CA-2319644-A1 (CA)
Inventor: RUBEN STEVEN M
IPC: C12N15/15
Filed: 1999-02-04
Abstract: La présente invention concerne de nouvelles protéines humaines sécrétées, ainsi que des acides nucléiques isolés contenant les régions codantes des gènes codant ces protéines. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps, et des méthodes de recombinaison permettant de produire les protéines humaines sécrétées. L'invention concerne enfin des méthodes diagnostiques et thérapeutiques utilisées dans le traitement de troubles associés à ces nouvelles protéines humaines sécrétées.
Patent CA-2324921-A1 (CA)
Title: Trisubstituted 1,3,5-triazine derivatives for treatment of hiv infections
Inventor: JANSSEN PAUL ADRIAAN JAN
IPC: C07D403/12
Filed: 1999-03-24
Abstract: This invention concerns the use of the compounds of formula (I) the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein A is CH, CR4 or N; n is 0, 1, 2, 3 or 4; R1 and R2 are each independently selected from hydrogen, hydroxy, C1-12alkyl, C1-12alkyloxy, C1-12alkylcarbonyl, C1-12alkyloxycarbonyl, aryl, amino, mono-or di(C1-12alkyl)amino, mono- or di(C1-12alkyl)aminocarbonyl wherein each of the aforementioned C1-12alkyl groups may optionally and each individually be substituted; or R1 and R2 taken together may form pyrrolidinyl, piperidinyl, morpholinyl, azido or mono- or di(C1-12alkyl)aminoC1-4alkylidene; R3 is hydrogen, aryl, C1-6alkylcarbonyl, optionally substituted C1-6alkyl; and each R4 independently is hydroxy, halo, C1-6alky1, C1-6alkyloxy, cyano, aminocarbonyl, nitro, amino, trihalomethyl or trihalomethyloxy; L is -X-R5 or -X-Alk-R6;  wherein R5 and R6 each independently are indanyl, indolyl or phenyl; each of said indanyl, indolyl or phenyl may be substituted; and X is -NR3-, -NH-NH-, -N-N-, -O-, -S-, -S(-O)- or -S(-O)2-; aryl is optionally substituted phenyl; Het is an optionally substituted aliphatic or aromatic heterocyclic radical; for the manufacture of a medicine for the treatment of subjects suffering from HIV (Human Immunodeficiency Virus) infection. It further relates to new compounds being a subgroup of the compounds of formula (I), their preparation and pharmaceutical compositions comprising them.
Patent CA-2329259-A1 (CA)
Title: Convection-enhanced delivery of aav vectors
Inventor: BANKIEWICZ KRYS
IPC: A61K47/48
Filed: 1999-05-26
Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
Patent CA-2331177-A1 (CA)
Title: A roller bit with parallel inlayed compacts
Inventor: CHEN ZHIHUA
IPC: E21B10/16
Filed: 2001-01-16
Abstract: This invention relates to a roller bit applying for the oil, natural gas, mine and geological drilling, and more particularly relates to a kind of roller bit with the parallel inlayed compacts, it includes head and cone, the compact land and the teeth-groove are arranged on the cone, the difference is that there are 2 to 3 compacts having the cylindrical body being arranged on the top of the base teeth along the teeth direction. The cutting performance of the present invention is similar to that of the oblate compacts, and, by utilizing the conventional cylindrical compacts, it is not only easy to process and with low manufacturing cost, but the bit can effectively drill through the stringered earth formation with both hard and soft formation and thus better economic benefit from drilling the stringered formation can be obtained.
Patent CA-2332470-A1 (CA)
Title: Procede de detection precoce des instabilites aerodynamiques dans un compresseur de turbomachine
Inventor: LECONTE THIERRY
IPC: F04D27/02
Filed: 2001-01-22
Abstract: L'invention consiste à faire l'acquisition de signaux délivrés par des capteurs équirépartis sur la circonférence du compresseur et à détecter, à partir des signaux normalisés, des événements pour lesquels les signaux normalisés présentent une absence de passage par une valeur zéro pendant une durée TZ au moins supérieure à une durée de passage de deux aubes mobiles successives devant le capteur. Une décision sur l'imminence d'une instabilité aérodynamique est ensuite prise après analyse des événements détectés et applications de critères de décision. Le critère de décision peut être basé sur la cadence de détection des événements et /ou sur la position spatio-temporelle des événements détectés sur l'ensemble des capteurs.
Patent CA-2334338-A1 (CA)
Title: Directed combinatorial compound library and high throughput assays for screening same
Inventor: SAHA UTTAM
IPC: A61K38/00
Filed: 1999-06-10
Abstract: A combinatorial library comprising a predetermined collection of nucleoside peptide molecules for inhibiting the transfer of a sugar from a selected sug ar nucleotide donor to a selected acceptor by a carbohydrate processing enzyme.  The nucleoside peptide molecule comprises (a) a nucleoside monomer; (b) a spacer monomer coupled to the nucleoside monomer wherein the spacer monomer comprises one or more amide linked amino acid residues, or a peptidomimetic;  and (c) cap monomers attached to the spacer monomer. The nucleoside peptide molecules differ from each other as to the identity of at least one element of the nucleoside monomer, spacer monomer, or cap monomer.
Patent CA-2334515-A1 (CA)
Title: Composition pharmaceutique contenant un inhibiteur de cox-2 et un inhibiteur de inos
Inventor: TINKER ALAN
IPC: A61P19/02
Filed: 1999-06-23
Abstract: L'invention concerne l'administration conjointe d'un inhibiteur de la synthase d'oxyde nitrique induite de la formule (I) et d'un inhibiteur de la cyclo-oxygénase 2 pour le traitement d'inflammations ou de maladies inflammatoires.
Patent CA-2334884-A1 (CA)
Inventor: ZHU BIN
IPC: H01M8/10
Filed: 1999-06-11
Abstract: L'invention concerne une pile à combustible destinée à la production d'énergie électrique et comprenant ce qui suit:  une chambre à combustible (1), une anode (2a), une cathode (2b), un électrolyte (3) déposé entre l'anode et la cathode, et une chambre à comburant (4), les chambres (1 et 4) renfermant l'anode, la cathode et l'électrolyte. Le combustible s'écoulant depuis la chambre à combustible est oxydé sur l'anode en produisant de l'énergie électrique. L'électrolyte (3) se présente comme un électrolyte céramique composite qui comprend dans le mélange au moins un sel et un oxyde.
Patent CA-2335040-A1 (CA)
Title: Microkeratome and method for performing corneal resections
Inventor: CARRIAZO CESAR C
IPC: A61B/
Filed: 2000-04-12
Abstract: A micro-keratone (10) includes a guide ring assembly (12) adapted for placement on the ocular globe, and means (14) for temporarily fixing the guide ring (12) to the ocular globe.      A cutting head (16) containing a cutting blade suitable for corneal resections is also provided.      A vertical support assembly (18) is connected to the guide ring (12), and supports the cutting head (16) for rotation about a horizontal axis. In one embodiment, the cutting blade has an arcu-ate cutting edge for cutting corneal resections.      A method relating to the use of straight, and ar-cuate cutting blades (54a) is also provided.
Patent CA-2336451-A1 (CA)
Inventor: WINTER BRUCE
IPC: H04N7/14
Filed: 2001-02-14
Abstract: A Personal Computer (PC) Based Real Time Interactive Videoconferencing System using a desktop or laptop central processing unit (CPU), or wireless Personal Digital Assistant (PDA) e.g. Palm Pilot, cell phone or pager. The standard system requires a CPU running at 166 megahertz or faster and 140 megabits of memory available on the C drive and capacity for the installation of a board or chipset, archiving and database software i.e. Production Assistant, videoconferencing software and security software and a SVGA monitor. The PC is connected to a Digital Subscriber Line (DSL) telephone line or a cable modem to obtain high speed Internet access to the World Wide Web through an Internet service provider for the propose of transmitting data to another computer. A digital video camera is connected to the CPU to record person/object to be transmitted. The CPU connected to a television provides full screen, full motion pictures creating real time interactive communication. A VCR connected to the CPU  allows all transmitted data to be simultaneously recorded and archived. Data can also be recorded and archived on a digital storage device such as a computer hard drive, a read or write CD-ROM and data tape devices for retrieval and editing depending on user requirements. Computers at all videoconference locations are linked together using the World Wide Web as the 'highway' which can be accessed using DSL Telephony, cable modem technology or wireless technology e.g. infrared, laser or cell phone.
Patent CA-2336646-A1 (CA)
Inventor: REAUX JAMES
IPC: E21B47/10
Filed: 1999-07-07
Abstract: The present invention is a combination wireline retrievable, side pocket locatable, fluid measurement and control assembly, which permits measurement and control of fluid from a first downhole production zone (C) while maintaining fluid flow through the tubing (50) from other downhole production zones (A, B).  The various components of the fluid measurement and control assembly (10) may be separately installed in or retrieved from by either wireline or coiled tubing intervention methods and can remain installed in the production tubing (50) while installing or retrieving other downhole tools through wireline or coiled tubing intervention methods.
Patent CA-2337079-A1 (CA)
Inventor: RISVIK KNUT MAGNE
IPC: G06F17/30
Filed: 1999-07-09
Abstract: A search system for information retrieval comprises a data structure in the form of a non-evenly spaced sparse suffix tree for storing suffixes of words and/or symbols, or sequences thereof, in a text T, a metric M comprising combining edit distance metrics for an approximate degree of matching respectively between words and/or symbols, or between sequences thereof, in the text T and a query Q, the latter distance metric including weighting cost functions for edit operations which transform a sequence S of the text into a sequence P of the query Q, and search algorithms for determining the degree of matching respectively between words and/or symbols, or between sequences thereof, in respectively the text T and the query Q, such that information R is retrieved with a specified degree of matching with the query Q.      Optionally the search system also comprises algorithms for determining exact matching such that information R may be retrieved with an exact degree of matching with the query Q. A method in the search system comprises generating the data structure as a word-spaced sparse suffix tree, storing sequence information of the words in the text T in the generated suffix tree, generating a combined edit distant metric for words or sequences thereof in the text T and a query word q or sequences thereof in the query Q and including word-weighting cost functions for the sequence-transforming edit operations, and determining the degree of matching between retrieved information R and a query Q. - Use in an approximate search engine.
Patent CA-2338549-A1 (CA)
Title: Puncture-resistant polyolefin membranes
Inventor: RADOVANOVIC PHILIP D
IPC: H01M50/491
Filed: 1999-07-01
Abstract: Briefly, in one aspect, the present invention provides puncture resistant microporous materials made of melt-processable semi-crystalline thermoplastic polymers. The microporous materials can be produced at relatively high rates and at low cost. Films and multilayer constructions made of the microporous materials and methods of making microporous materials also are provided.
Patent CA-2340472-A1 (CA)
Inventor: DALY RUTH S
IPC: G06F19/00
Filed: 2001-03-12
Abstract: Embodiments of the invention provide for an action to be performed on a target model based on changes in the notify model. The difference between this, and the previous examples, is that in the previous examples, the actions are performed against the notify model, not the target model. When an action needs to be performed based on a change in the target model, the previous examples of behavior are inadequate. Because the target model does not notify that it has been changed, a correlation between the notify model and target model will be used to determine what has changed in the target model. Given that the notify model and the target model are representations of the same data, if the notify model sends an event notification (which indicates that a change has occurred in the notify model), it can be deduced that the corresponding item in the target model has been changed, too. Based on the changes made in the notify model, and using a mapping of the linkages associating objects in the notify model to objects in the target model, the objects in the target model affected by the changes in the notify model are identified. The action (e.g., a validation check) is performed only on the changed parts of the target model.
Patent CA-2341907-A1 (CA)
Inventor: ANTEBI AMIT
IPC: G06F3/033
Filed: 1999-08-27
Abstract: A method and system for measuring the distance from a piezoelectric substance (10) by transmitting an electromagnetic pulse (14) to the piezoelectric substance so as to generate an acoustic pulse (15) in response thereto. The acoustic pulse is sensed by an acoustic sensor (12) displaced from the piezoelectric substance by an unknown distance, and a time interval between initiation of the electromagnetic pulse and receipt of the acoustic pulse is measured. The distance between the piezoelectric substance and the acoustic sensor is computed by multiplying the measured time interval by the speed of sound, which is known. Upon striking the piezoelectric surface against a surface a modified echo characteristic of the acoustic pulse may be detected.  This allows operation of one of a plurality of switches to be detected. By using multiple sensors, the spatial location of the switch can be computed and this allows the specific switch to be identified in a computer keyboard adapted for use with a computer but not physically connected thereto.
Patent CA-2346829-A1 (CA)
Inventor: LAM PETER KWOK HING
IPC: C08G18/76
Filed: 1999-12-23
Abstract: A coating composition comprising: i) diphenylmethane diisocyanate, and ii) a hydroxyl functional compound which is a polyester having secondary hydroxyl groups, the secondary hydroxyl groups being the product of a reaction between a carboxylic acid group and an epoxide group, the composition containing substantially no reactive diluent which are aldimines, ketimines or aspartic esters.
Patent CA-2347508-A1 (CA)
Title: Improved acoustical ceiling tiles
Inventor: TINIANOV BRANDON DILLAN
IPC: E04B1/84
Filed: 2001-05-10
Abstract: A system for improved sound absorption, including a substrate of porous insulation material and of a first air flow resistance, and a facing material attached to the substrate and of a second air flow resistance, wherein a total system resistance is a combination of the first and second air flow resistances, and wherein the total system resistance and the second air flow resistance are of relatively low values.
Patent CA-2348335-A1 (CA)
Title: Burner nozzle with curved head
Inventor: HUTCHINSON THOMAS F JR
IPC: F23D14/06
Filed: 2001-05-23
Abstract: A burner nozzle includes a burner tube that extends along a central axis and has an inlet end portion for receiving combustible gas and air. The burner tube extends along the central axis from the inlet end portion to an outlet end portion for releasing a mixture of gas and air.      A curved head with a plurality of openings and an imperforate portion is connected to the outlet end portion.      The openings and imperforate portion of the curved head create a transverse flow of gas and air out of the curved head to produce a shaped flame. A burner assembly may include a combustion tube in which the burner nozzle is disposed and connected. The burner nozzle is used in a method of widening and shaping a flame.
Patent CA-2348897-A1 (CA)
Inventor: TACK JORIS JOZEF GUSTAAF
IPC: B65D85/07
Filed: 1999-11-04
Abstract: The present invention is directed to a container for wetted wipes, comprising a container body with at least one opening, a stationary cover being fitted on, or integrated to said container body, said stationary cover comprising at least one dispensing opening through which the container contents is removed, a movable lid which is movably attached to said stationary cover, or is an integral movable part of the stationary cover, so as to reversibly close said dispensing opening, the container being characterized in that a gas-proof means is located between said stationary cover and said movable lid, for providing a gas-tight barrier between the inside and the outside of the container when the movable lid is in the closed position. Preferably, the tub also comprises a spring element and a releasable lock for automatic opening of the movable lid.
Patent CA-2349740-A1 (CA)
Title: Two-stage fishing bobber
Inventor: BENNIS GARY L
IPC: A01K93/00
Filed: 2001-06-06
Abstract: A two-stage fishing bobber including a bobber main body normally buoyable in a body of water with the bobber main body having an opening extending through a vertical float axis of the bobber main body and a slideable rod slidably positioned in the cavity of the bobber main body with the slideable rod normally resiliently maintained in the bobber main body in an up position but downwardly displaceable with respect to the bobber main body in response to a first force on the fishing line. In one embodiment the force is sufficient to displace the slideable rod with respect to the bobber main body but not sufficient for a viewer to discern the displacement of the bobber main body with respect to the body of water to thereby provide a first-stage visually indication. In another embodiment the force to depress slidable rod is sufficient to overcome at least some if not all of the buoyant force of the bobber main body to thereby allow the simultaneous submersion of the bobber main body and the displacement of the member with respect to the bobber main body so as to provide gradual resistance in addition to two-stage visual indications.
Patent CA-2351156-A1 (CA)
Title: A bioprocess for the generation of pluripotent cell derived cells and tissues
Inventor: ZANDSTRA PETER W
IPC: C12N5/00
Filed: 2001-07-04
Abstract: The present inventors identified aggregation of embryoid bodies (EBs) as the cause of the difficulty in generating large numbers of the embryonic stem cells (ES) cell-derived tissues. To counter this, the invention provides a novel bioprocess where aggregation of EBs is physically prevented, such as by an encapsulating matrix, Liquid Suspension Culture- encapsulated (LSCe). As a result, EBs can be cultured in high cell density, well-mixed systems. Well-mixed conditions facilitate measurement and control of the bulk media conditions and allow for the use of scalable bioreactor systems for clinical production of tissue. Therefore, LSCe enables generation of ES cell-derived tissue on a clinical scale. The invention is also applicable to other types of pluripotent cells
Patent CA-2352879-A1 (CA)
Inventor: MOORE THOMAS C
IPC: A61B1/005
Filed: 1999-12-07
Abstract: An ultrasonic imaging catheter is used to generate a three-dimensional image of an organ having a relatively large cavity, such as, e.g., a heart. The catheter includes an elongate catheter body having an acoustic window formed at its distal end. The catheter further includes an imaging core, which includes a drive cable with a distally mounted ultrasonic transducer. The transducer is disposed in the acoustic window and is rotationally and longitudinally translatable relative thereto, providing the catheter with longitudinal scanning capability. The catheter further includes a pull wire, which is connected to the distal end of the catheter body, such that longitudinal displacement of the pull wire causes the acoustic window to bend into a known and repeatable arc. The catheter can then be operated to generate a longitudinal scan of the organ through the arc, i.e., a multitude of a cross-sectional imaging data slices are generated along a continuously varying multitude of imaging planes, which intersect all regions of the body organ. In this manner, a three-dimensional image depicting the entire body organ can be generated from a single longitudinal scan.
Patent CA-2355229-A1 (CA)
Inventor: KOPERNICKY JAROSLAV J
IPC: G01M1/28
Filed: 2001-08-07
Abstract: A method for the balancing of the automotive and aircraft wheel, in which imbalances are indicated and compensated in the manner, to assure that weight of the wheel is evenly distributed to meet a real forces in the wheel ( 1 ), rolling on the road (2), where every point of the peripheral mass of the wheel follows the cycloid curve (3). Thus, the imbalance indication has to be done by rolling the wheel in the direction of rotation, having a bottom of the wheel following the road. A physical contact with the road is not necessary. This is to withstand a real stress on the tire when the section of the mass of the wheel is accelerated from zero velocity (when touching the road) (4), to double velocity of the vehicle, while moving at the top of the tire (wheel) (5). A stress is in opposite direction when it is decelerated back to the zero (6). The method presented has to meet requirements on the wheel assembly, to withstand a stress force, which repeats with every turn of the wheel and increases by a square of the real velocity. The balancing - compensation is done rather by removing the weight from the heavier area instead of adding the weight to the lighter area to counterbalance the heavier part of the wheel (tire), as is the present method. Up to date methods and designs indicate and compensate for imbalance only in stationary rotating wheels, efficient only for a stationary rotating wheels. Forces of the real rolling movement and accelerations on the cycloid path are until now ignored due to the acceptance of the preferred frame of reference. Accelerometers placed on the rolling wheel show a different reading than a stationary rotating wheel. Thus the preferred frame of reference doesn't represent reality, therefore all methods based on the old popular notion of the free choice of a frame of reference do not serve the purpose. The method of the wheel rolling on the rotating drum or rollers used in automotive industry has to be considered also as a stationary, meaning - not sufficient. Balancing methods of "automatic" internally distributed (balancing) mass can be right from this invention's point of view but appear having difficulty to control the distribution of balancing material and also limited reliability. For better appreciation of the invention significance, let us consider a tire of a jet landing by 300mph having all surface points accelerated from zero - while touching the runway -to 600mph plus, when on the top of the wheel, then decelerating back to zero.  This repeats by each turn of the wheel. The accelerating stress is combined with the load pressure. This invention provides means to minimize this stress and increase of a safety of the vehicle.
Patent CA-2360654-A1 (CA)
Inventor: KACHER MARK LESLIE
IPC: C11D3/386
Filed: 2000-02-08
Abstract: Disclosed are detergent compositions comprising organic diamines, anionic surfactants and amphoteric surfactants including amine oxide for hand dishwashing which, by incorporating certain organic solvents, results in a liquid dishwashing detergent composition that is not only a more effective cleaning agent, but also offers improved physical and enzymatic stability and more convenient rheology and handling characteristics than typical liquid dishwashing compositions.