baber/WOPTO huggingface dataset:
Patent DE-60138764-D1 (DE)
Inventor: ETZERODT MICHAEL
IPC: C07K14/47
Filed: 2001-12-13
Granted: 2009-07-02
Abstract: A novel family of protein libraries comprising CTLDs (C-type Lectin-Like Domains) in which internal polypeptide loop-regions lining the ligand binding sites in CTLDs have been replaced with ensembles of completely or partially randomised polypeptide segments. Tetranectin CTLDs were chosen as framework for the preferred embodiment of the invention; and versatile phagemid vectors useful in the generation and manipulation of human and murine tetranectin CTLD libraries are disclosed as part of this invention. Tetranectin CTLDs in monomeric as well as in trimeric form are efficiently displayed as gene III fusions in fully functional form by the recombinant fd phage display vector. CTLD derivatives with affinity for new ligands may readily be isolated from libraries of vectors displaying CTLDs, in which loop-regions have been randomised, using one or more rounds of enrichment by screening or selection followed by amplification of the enriched subpopulation in each round.  The efficiency with which protein products containing CTLDs with new binding properties can be produced, e.g. by bacterial expression and in vitro refolding, in mono-, tri-, or multimeric formats provides important advantages in terms of simplicity, cost and efficiency of generation, production and diagnostic or therapeutic applications in comparison to recombinant antibody derivatives.
Patent DE-60142766-D1 (DE)
Inventor: JAWAORSKI RICHARD C
IPC: H04L1/20
Filed: 2001-06-08
Granted: 2010-09-23
Abstract: A system and method for testing a portion of a cable network provides a pattern generator (600), addresser (602), forward error corrector (606), and comparator (604). The system and method is particularly adapted to testing the upstream channel in a cable network. The pattern generator (600) generates a test signal. The addresser (602) addresses the signal to a known server and also instructs the known server to return the test signal to the test system. The forward error corrector (606) corrects errors introduced in the test signal in transmission from the known server to the test system. The comparator (604) then compares the returned test signal to the originally transmitted test signal to determine the performance of the back channel. Preferably, the comparator (604) uses a bit error rate test to determine the performance of the back channel. <IMAGE>
Patent DE-60202847-D1 (DE)
Inventor: KEMPER CHARLES
IPC: G06F17/30
Filed: 2002-02-28
Granted: 2005-03-10
Abstract: An interaction system for enabling a user of information systems to interact with the information systems and a method of transmitting user queries from a speech, image or handwriting recognition system to the information systems. The interaction system is connectable to at least one recognition system and at least one information system and comprises at least one domain module for containing phrase setups constructed based on object classes, attribute classes and action classes that are common to all information systems of a given application domain and are provided to be tailored to a specific information system of the application domain by applying object, action and attribute types proper to the information system and specific object, action and attribute instantiations, obtained from the specific information system, in order to define a grammar essentially consisting in a set of term elements comprising specific object, attribute and action instantiations of those object, action and attribute types and a set of rules governing the use of these term elements in a set of valid user query phrases for interaction between the user and the specific information system through the recognition and interaction systems. The interaction system can also comprise at least one generic module, connectable to a recognition system, and/or at least one adapter module, connectable to an information system. The transmission method comprises the steps of defining the grammar and converting user queries into valid user query phrases according to the grammar and/or sets of term elements and rules of the grammar.
Patent DE-60218458-D1 (DE)
Inventor: MARTIN NIALL M B
IPC: A61P43/00
Filed: 2002-04-30
Granted: 2007-04-12
Abstract: Derivatives of isoquinolinone and dihydrolisoquinolinone, and related compounds, and their use as pharmaceuticals in the treatment of a disease by inhibition of the enzyme poly(ADP-ribose)polymerase ("PARP") are disclosed.
Patent DE-60218650-D1 (DE)
Inventor: LAWRENCE CHRISTOPHER ROBERT
IPC: B01D53/26
Filed: 2002-02-18
Granted: 2007-04-19
Abstract: A surface (30) suitable for promoting the formation of droplets of liquid (35) is provided comprising alternating regions of liquid repelling (32) and liquid attracting (33) material in at least one direction across the surface wherein the diameter of the droplets is controlled by the size of the smallest dimension of the liquid attracting material. The surface (30) may be textured and/or form a pattern. Also disclosed are a method and a system of collecting a liquid (35) carried by or condensed out of a vapour comprising passing a vapour across such a surface (30) and a method of purifying a liquid by passing a vapour containing droplets of a liquid over such a surface.
Patent DE-60219040-D1 (DE)
Inventor: MANARESI NICOLO
IPC: C12Q1/68
Filed: 2002-05-02
Granted: 2007-05-03
Abstract: First entities consisting in cells or microorganisms (BIO) and second entities consisting in compounds or compound units, carried typically by microbeads (BEAD), are trapped selectively within closed movable potential cages (S1) by means of dielectrophoretic force generated by mutually opposed electrodes (M1, M2). The cages are set in relative motion so as to bring about the interaction of selected first and second entities, causing the cages containing them to fuse, whereupon results are obtained preferably by reinstating the original cages and/or observing previously empty adjacent cages. The procedure takes place in a device (DE) with two separate chambers (F, FL) connected one to the other by way of a narrow passage (D) and finished with respective selectively controllable inlets and outlets (I1, I2; O1, O2) through which a liquid or semi-liquid buffer (L) can be pumped in or out.
Patent DE-60221564-D1 (DE)
Inventor: ROOVERS ANTONIUS ADRIANUS
IPC: C10G49/00
Filed: 2002-11-15
Granted: 2007-09-13
Abstract: A method for the hydroprocessing of a heavy hydrocarbonaceous feedstock in a reaction zone having a bed containing a fixed array of porous catalyst particles by contacting the feedstock with a hydrogen-containing gas under conditions which allow distributing the feedstock predominantly in liquid phase under super-atmospheric process conditions at elevated temperature over the catalyst bed for downward flow in contact with the catalyst particles and introduction of the hydrogen-containing gas in the reaction zone below the catalyst bed in order to establish countercurrent contact of the upwardly flowing gas with the downcoming liquid and withdrawing treated liquid below the catalyst bed and withdrawing fluid depleted in hydrogen above the catalyst bed, in which process the catalyst bed has a void volume fraction below 0.5, whilst the countercurrent liquid/gas contacting is carried out under conditions which allow the Peclet number of the liquid to be in the range between 0 and 10.
Patent DE-60225018-D1 (DE)
Inventor: WIGHT JAMES STUART
IPC: H04B7/08
Filed: 2002-07-26
Granted: 2008-03-27
Abstract: A combiner for a diversity radio receiver wherein amplitude inversion of either received signal is performed, on a selection basis, in order to maximize the resultant output combined signal. The strength of each diversity signal is monitored as well as the strength of the combined output signal. A gain control engine combines the stronger signal with either the inverted or non-inverted weaker signal to maximize the combined output (resultant) signal strength. According to another embodiment the combiner may additionally perform an amplitude adjustment whereby the in-channel noise power is also monitored and the individual channel signal-to-noise ratios are used to adjust the amplifier gains. In this embodiment the individual channel signal-to-noise ratios plus the strength of the combined output signal are used to decide whether to invert the weaker signal before combining the received signals.
Patent DE-60229789-D1 (DE)
Inventor: SAIGAL JAGDISH CHAND
IPC: C07C213/08
Filed: 2002-06-13
Granted: 2008-12-18
Abstract: A process for the preparation of hydroxy(cycloalkane/cyclokene) phenylethyl amine of the general formula (III) comprising alkylation of its precursor amine of general formula (II) which is in turn produced by an effective reduction process from its precursor cyanide having the general formula (I) using Raney Nickel (CORMIII) as catalyst where, either of R5 and R6 independently could be in meta or para position and R5, R6 are independently hydrogen, hydroxyl, alkyl, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, allkanamido, halo, trifluoromethyl, or taken together methylenedioxy, n is 0, 1, 2, 3, 4, R7 is hydrogen of alkyl of 1-7 carbon atom, R1 IH or alkyl of 1-3 carbon atom and R2 is alkyl 1-3 carbon atom, the dotted line represents optional unsaturation. Compounds of formulae IV, V and VI are respectively derivatives of compounds I, II and III respectively.
Patent DE-60233074-D1 (DE)
Inventor: BAURAND GILLES
IPC: H01H1/00
Filed: 2002-12-17
Granted: 2009-09-03
Abstract: The pole contact (C1,C2,C3) wear determination method has an electromagnet (20) with movement controlled by a field coil (21). Wear is determined on the basis of the contact wear stroke produced during a movement closing the electromagnet. An electric signal is measured on the conducting status of a power pole, by measuring the excitation current flowing in the coil on a time basis. The measured wear time is then compared with the initial travel time.
Patent DE-60234273-D1 (DE)
Inventor: HUSH GLEN
IPC: G11C11/34
Filed: 2002-12-16
Granted: 2009-12-17
Abstract: A method of operating a memory cell (122), said method comprising: precharging a bit line (118) to a first voltage; applying a second voltage to a first terminal of a memory element; and connecting a second terminal of said memory element to said bit line to produce a voltage across said memory element sufficient to write a predetermined resistance state into said memory element.
Patent DE-60234522-D1 (DE)
Inventor: RUNK DAVID M
IPC: B21D5/02
Filed: 2002-08-07
Granted: 2010-01-07
Abstract: An American style press brake tool and tool holder having a safety key. The holder has a body with walls defining a downwardly open, tool receiving recess having a top, a downwardly facing force-delivering shoulder adjacent the bottom of said recess, and a shelf within said recess having an upwardly facing surface spaced upwardly from said force-delivering shoulder. The tool comprises a body having a lower work-engaging surface, an upwardly facing force-receiving shoulder engageable with the shoulder of the tool holder, and an upwardly extending tang receivable in said recess, the upper end of the tang being spaced from the top of the recess. A manually operable actuator is spaced below said force-receiving shoulder, and a safety key is coupled to the actuator for movement horizontally into and out of alignment with the shelf between locked and unlocked positions, respectively.
Patent DE-60235130-D1 (DE)
Inventor: HENDRIX JAMES A
IPC: C07D215/40
Filed: 2002-02-15
Granted: 2010-03-04
Abstract: The invention relates to heterocyclic substituted carbonyl derivatives of the formula I   
that display selective binding to dopamine D 3  receptors and are useful for treating central nervous system disorders associated with the dopamine D 3  receptor activity in a patient in need of such treatment comprising administering to the subject a therapeutically effective amount of said compounds for alleviation of such disorder. The central nervous system disorders that may be treated with these compounds include Psychotic Disorders, Substance Dependence, Substance Abuse, Dyskinetic Disorders (e.g. Parkinson's Disease, Parkinsonism, Neuroleptic-Induced Tardive Dyskinesia, Gilles de la Tourette Syndrome and Huntington's Disease), Dementia, Anxiety Disorders, Sleep Disorders, Circadian Rhythm Disorders and Mood Disorders. The subject invention is also directed towards processes for the preparation of the compounds described herein as well as methods for making and using the compounds as imaging agents for dopamine D 3  receptors.
Patent DE-60235424-D1 (DE)
Inventor: GEORGE AUBERT THIBAUD MICHEL MARIE
IPC: B60N2/015
Filed: 2002-04-25
Granted: 2010-04-08
Abstract: The sealing device comprises a flexible strip (4) fixed to the wall (1) so as to be elastically pressed against it under the hole (2) so as to seal it. The strip is elastically moved away from the orifice during the introduction of the fixing means (3) in the hole.
Patent DE-60237512-D1 (DE)
Inventor: REDDY PREMKUMAR E
IPC: C07D233/64
Filed: 2002-02-28
Granted: 2010-10-14
Abstract: N-(Aryl)-2-arylethenesulfonamides and pharmaceutically acceptable salts and compositions thereof are useful as antiproliferative agents, including, for example, anticancer agents. They are also useful as radioprotective agents.
Patent DE-60237858-D1 (DE)
Inventor: KIM JUN SUNG
IPC: C12N15/87
Filed: 2002-02-05
Granted: 2010-11-18
Abstract: The present invention relates to a peptide vector comprising a leader peptide, a linker DNA, and a desired gene. This peptide vector can achieve gene transfer without cell specificity and does not induce host immune responses. <IMAGE>
Patent DE-60305901-D1 (DE)
Inventor: GABEL B
IPC: A61K9/70
Filed: 2003-03-31
Granted: 2006-07-20
Abstract: A delivery device for delivering a substance intradermally into the skin of a patient including a housing (12) for contacting the surface of the skin and a disposable cartridge (14) to be received in the housing. The cartridge includes an internal reservoir containing a substance to be delivered to the patient, a plurality of micro skin penetrating members (80) and a fluid channel (76) extending between the micro skin penetrating members and the reservoir. The housing includes a bottom wall with a central opening and a cover member (32). The cartridge is positioned in the housing with the micro skin penetrating members extending through the central opening of the bottom wall and positioned on the surface of the skin of a patient. The cover (32) is closed onto the cartridge (14) to dispense the substance from the cartridge through the micro skin penetrating members and into or through the skin of the patient.
Patent DE-60308452-D1 (DE)
Inventor: KIMURA KEIICHI
IPC: D21F7/08
Filed: 2003-06-27
Granted: 2006-11-02
Abstract: In a shoe press belt (10) of a papermaking machine, the part of the paper web-facing layer in which water-holding grooves (40) are formed is composed of a surface sublayer (52), having a relatively low hardness, and an underlying layer (43) having a relatively high hardness. The higher hardness of the underlying layer (43) prevents cracks from forming where the cross-sectional shape of the grooves (40) tends to change as the belt is compressed. The lower hardness of the surface sublayer (52) prevents the formation of cracks as a result of forces acting on the belt in the direction opposite to the machine direction at the nip location in a papermaking machine. <IMAGE>
Patent DE-60309138-D1 (DE)
Inventor: HIRATA HIDEKI
IPC: G11B7/254
Filed: 2003-03-10
Granted: 2006-11-30
Abstract: An optical information medium having a light transmission layer obtained by curing a composition containing a urethane di(meth)acrylate (A) of the formula (I) and the other urethane di(meth)acrylate (B), and having a tensile elastic modulus of 600 to 1300 MPa at 25 DEG C and a light transmittance of 80% or more at wavelength of 400 nm (in the formula, R1 = an alicyclic diisocyanate residue, R2 = an alkylene group or an organic group containing a cycloalkyl group or ester bond, R3 = H or methyl group.): <CHEM>
Patent DE-60309562-D1 (DE)
Inventor: DYCHE ANTHONY
IPC: A61M11/00
Filed: 2003-01-17
Granted: 2006-12-21
Abstract: A nebulizer includes nebulization device for nebulizing a substance and a reservoir having a metering chamber arranged so as to feed a substance to be nebulized to the nebulization device and a second chamber arranged to hold and retain any of this substance in excess of the volume held in the metering chamber.
Patent DE-60310975-D1 (DE)
Inventor: WOLTERING A
IPC: A61P5/00
Filed: 2003-10-13
Granted: 2007-02-15
Abstract: The present invention relates to a method of treating a warm-blooded animal, especially a human, having hyperparathyroidism comprising administering to said animal a therapeutically effective amount of an epothilone derivative of formula I or a pharmaceutically acceptable salt thereof.
Patent DE-60312682-D1 (DE)
Inventor: CHOMCZYNSKI PIOTR
IPC: A61P37/08
Filed: 2003-06-09
Granted: 2007-05-03
Abstract: A method for topically treating rosacea is disclosed. In this method, an active material having the formula given below is applied to the patient at the site of said rosacea: wherein R<1 >is selected from -OH and C1-C3 alkyl OH; and R<2>, R<3>, R<4>, R<5 >and R<6 >are independently selected from -H, -OH, C1-C6 alkyl, and C3-C6 cycloalkyl. Preferred active materials include 1,2-cyclohexanediol, 1,3-cyclohexanediol, 1,4-cyclohexanediol, and mixtures of those materials. Methods for treating acne vulgaris, as well as colds, flu, sinusitis, and ear infections, using these actives are also disclosed.
Patent DE-60313286-D1 (DE)
Inventor: SHAH PETER JIVAN
IPC: H04B17/00
Filed: 2003-02-03
Granted: 2007-05-31
Abstract: Techniques are disclosed for compensating for second-order distortion in a wireless communication device. In a zero-intermediate frequency (IF) or low-IF architecture, IM2 distortion generated by the mixer (20) results in undesirable distortion levels in the baseband output signal. A compensation circuit (104) provides a measure of the IM2 distortion current independent of the radio frequency (RF) pathway to generate an IM2 calibration current. The IM2 calibration current is combined with the baseband output signal to thereby eliminate the IM2 currents generated within the RF pathway. In one embodiment, the calibration is provided at the factory during final testing. In alternative embodiment, additional circuitry (156, 158) may be added to the wireless communication device to provide a pathway between the transmitter (150) and the receiver (146). The transmitter signal is provided to the receiver to permit automatic calibration of the unit. An internal signal source (162) may be used in place of the transmitter (150). The auto-calibration may be performed to eliminate IM2 distortion or permit optimization of the circuit to minimize other forms of distortion or interference.
Patent DE-60313482-D1 (DE)
Inventor: MUGNIER NICOLAS
IPC: C01F7/062
Filed: 2003-10-21
Granted: 2007-06-06
Abstract: Process for the treatment of bauxite (10) by alkaline digestion, typically using the Bayer process in order to obtain alumina hydrate, characterized in that ground bauxite (11, 15) is added directly into an alkaline solution (21a) that is drawn off and that will be reinserted into the Bayer aluminate liquor circuit (20), the said alkaline solution (21a) being heated at a temperature such that after the said ground bauxite (11, 15) and the said alkaline solution have been brought into contact, the temperature of the slurry resulting from this mix is greater than a temperature close to the boiling temperature at atmospheric pressure, in other words typically greater than 95° C. and preferably greater than or equal to the boiling temperature at atmospheric pressure.
Patent DE-60315584-D1 (DE)
Inventor: BACK MARK A
IPC: E04B7/04
Filed: 2003-12-15
Granted: 2007-09-27
Abstract: A multi-piece eaves beam (30, 32) comprises at least one base member (30) and an elongate upper member (32); the base member (30) has a base portion (36) from which first and second wall members (42, 44) extend, the base portion (36) and wall members (42, 44) define a channel section, the base member (30) being securable to an underlying wall (29) by a fastener (91) extending through the base member (30) to the wall (29), the upper member (32) has rafter support means (70) and first and second leg members (56, 58), the upper member (32) is shaped and dimensioned to be locatable, in use, above said base member (30) with the leg members (56, 58) adjacent the wall members (42, 44); wherein the base member (30) and upper member (32) are securable together by a fastener (92) extending through one of said leg members (56, 58) and one of said wall members (42, 44). This facilitates installation of the eaves beam and allows the roof to be pre-assembled, taken to the work site and installed. <IMAGE>
Patent DE-60319398-D1 (DE)
Inventor: LEVI GUY
IPC: A23L19/00
Filed: 2003-08-29
Granted: 2008-04-10
Abstract: A stabilized fruit pulp is described. The stabilized fruit pulp has not been subjected to temperatures that exceed 90 degrees centigrade, has substantially no active polyphenol oxidase, and is suitable for use in puree compositions that can be used in dressings, dips and spreads.
Patent DE-60323570-D1 (DE)
Inventor: PELLEGRINI PIETRO
IPC: F41C33/04
Filed: 2003-07-16
Granted: 2008-10-30
Abstract: A holster safety device to prevent a pistol from accidentally slipping out of its holster (1) or being pulled out by unauthorized persons, comprising a strap (2) rotatably attached to the holster (1) to fit around the pistol inserted in the holster substantially in correspondence to the butt of said pistol, an arm (6) integral with said strap (2) extending from a box (4) integral with said holster and terminating with a push-button (7), said arm (6) being hinged to said box (4) in such a way as to permit its being rotated between two angularly spaced positions in which said strap is, respectively, engaged on the butt of the pistol and removed therefrom. Within said box there are provided means (10, 11) for locking the rotation of said arm (6) that can be released following pressure exerted on said push-button (7) and with consequent possibility of making said arm (6) slide in the axial direction. The push-button (7) is hinged to the end of the arm (6) and can be brought into two angularly spaced positions, the shape of said push-button being such that in one of said positions one of its sides (7a) bears against said box (4), thus preventing the axial sliding of said arm and therefore also the release of its rotation, there being provided means (17) for locking said push-button in each of said angularly different positions. <IMAGE>
Patent DE-60324413-D1 (DE)
Inventor: LEE JONG-LAM
IPC: H01L27/08
Filed: 2003-03-31
Granted: 2008-12-11
Abstract: A light-emitting device, comprising: 
a conductive support layer (156); 
a first ohmic contact (150) over the conductive support layer; 
a first type GaN-based layer (128) over the first ohmic contact; 
an active layer (126) over the first type GaN-based layer; 
a second type GaN-based layer (124) over the active layer; and 
a second ohmic contact (160) over the second type GaN-based layer; 
wherein the light generated in the active layer emits mainly in the direction of at least one of 
the first type GaN-based layer and the second type GaN-based layer.  The device may comprise a passivation layer (162) formed after substrate transfer.
Patent DE-60327925-D1 (DE)
Inventor: LEVY GARY
IPC: A61K38/18
Filed: 2003-02-28
Granted: 2009-07-23
Abstract: Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of a soluble fgl2 protein or a nucleic acid encoding a soluble fgl2 protein. The methods are useful in preventing graft rejection, autoimmune disease, and allergies.