baber/WOPTO huggingface dataset:
Patent CA-2445746-C (CA)
Inventor: JENSEN MICHAEL
IPC: A61K39/00
Filed: 2002-04-30
Granted: 2012-09-18
Abstract: The present invention relates to chimeric transmembrane immunoreceptors, named "zetakines", comprised of an extracellular domain comprising a soluble receptor ligand linked to a support region capable of tethering the extracellular domain to a cell surface, a transmembrane region and an intracellular signalling domain. Zetakines, when expressed on the surface of T  lymphocytes, direct T cell activity to those specific cells expressing a receptor for which the soluble receptor ligand is specific. Zetakine chimeric immunoreceptors represent a novel extension of antibody-based immunoreceptors for redirecting the antigen specificity of T cells, with application to treatment of a variety of cancers, particularly via the autocrin/paracrine cytokine systems utilized by human maligancy. In a preferred embodiment is a glioma-specific immunoreceptor comprising the extracellular targetting domain of the IL-13R.alpha.2-specific IL-13 mutant IL-13(E13Y) linked to the Fc region of IgG, the transmembrane domain of human CD4, and the human CD3 zeta chain.
Patent CA-2451071-C (CA)
Title: Compact reactor for use in a hydrogen generation/fuel cell system
Inventor: PHILLIPS CORY
IPC: C01B3/48
Filed: 2002-06-18
Granted: 2009-10-27
Abstract: A reactor module (40) having one or more than one heat exchanger (1a and 1b) , a chamber block (2) capable of being charged with a catalyst (24), and a platform are assembled in a unit in which separate fluid flows of reactants and heat media are directed by manifolds (26) and ducts intrinsically formed in the module (40). Multiple reactor modules (45a and 45b) may be interconnected to form a further reactor module unit and the interconnected reactor units may in turn be configured for a large system with a high power rating.
Patent CA-2456971-C (CA)
Title: Composition for removing dissolved oxygen from a fluid
Inventor: CHARKHUTIAN KOSTAN B
IPC: B01D19/04
Filed: 2002-08-05
Granted: 2010-11-09
Abstract: This invention relates to compositions, which are useful in removing dissolved oxygen from a fluid stream, preferably an aqueous stream. The compositions comprise blend of an oxime and a primary hydroxylamine. This invention also relates to a process for removing oxygen from an aqueous system, which comprises adding an oxime and a primary hydroxylamine to a fluid system.
Patent CA-2460105-C (CA)
Inventor: HORTON WILLIAM
IPC: B60N2/75
Filed: 2004-03-04
Granted: 2007-11-27
Abstract: A juvenile vehicle seat assembly includes a seat having a side wall, an armrest mount coupled to tile side wall of the seat, and an armrest coupled to the armrest mount for movement relative to the seat about a pivot axis between a raised position and a lowered position. The armrest mount includes an outer wall formed to define a first notch and a second notch spaced-apart from the first notch. The armrest includes an outer wall and a top wall coupled to the outer wall to cooperate with the outer wall to define a cavity formed to receive the outer wall of the armrest mount therein. A lug of the armrest is located within the first notch of the armrest mount in the raised position arid is located within the second notch of the armrest mount in the lowered position.
Patent CA-2473630-C (CA)
Inventor: ARMSTRONG JOSEPH R
IPC: A61F2/844
Filed: 2000-01-21
Granted: 2008-07-29
Abstract: The present invention is an improved endovascular device particularly useful for use in transjugular intrahepatic portosystemic shunt (TIPS) procedures. The device employs a two-part stent-graft construction that provides a low permeability membrane to line the shunt and an uncovered stent portion designed to reside in the portal vein. The device provides numerous benefits over previous stems and stent-grafts used in TIPS procedures, including being more compact to deliver, being easier to accurately deploy, a controlled compacted surface with tucked apices, an improved stent winding pattern, and being more flexible in delivery and use.
Patent CA-2476400-C (CA)
Title: Method and device for generating logic control units for railroad station-based vital computer apparatuses
Inventor: MINKOWITZ CYDNEY
IPC: B61L27/00
Filed: 2003-02-18
Granted: 2011-04-19
Abstract: A method of generating logic control units for railroad station-based vital computer apparatuses, i.e. in railroad station system control units comprising at least one vital computer which, on the basis of a control program operating in combination with a logic unit, sends state switching controls to so-called yard elements and receives state feedback and/or diagnostic signals from said yard elements, said logic unit being generated automatically by a program, based on the surrounding conditions as defined by the station diagram and by a state table, said logic unit being a network of circuits with components operating according to Boolean logic functions and appropriately structured in compliance with the station diagram and with the state table, or said logic control unit being a program which includes algorithms composed of Boolean logic functions, which operate like networks of Boolean logic circuits. According to the invention, a step for checking the correctness of the automatically generated logic unit is provided, which checking step includes the following steps: parallel generation of two logic control units, according to the same station diagram and the same state table, each being generated by a different generation program; comparison between the networks of logic circuits or network-simulating logic programs provided by the two different programs to check for structural differences.
Patent CA-2478887-C (CA)
Title: Methods and devices for selective disruption of fatty tissue by controlled cooling
Inventor: ANDERSON RICHARD ROX
IPC: C12N5/077
Filed: 2003-03-17
Granted: 2013-08-13
Abstract: The present invention relates to a device and methods for use in the selective disruption of lipid-rich cells by controlled cooling. The device comprises a treatment unit, 107, with a cooling/heating element, 110, for cooling or heating selected skin areas and a control unit, 105.
Patent CA-2479052-C (CA)
Inventor: LEVY DAVID H
IPC: H01H9/00
Filed: 2003-05-23
Granted: 2005-11-22
Abstract: A keypad with both elevated (11) and non-elevated (22) key regions, and key switches (12) disposed beneath both types of key regions. The non-elevated k ey regions each provide corresponding character output based on an operation algorithm that considers activation of at least one adjacent elevated key region as well as activation of the switch below the non-elevated key region . The keypad includes a keymat (41) that is rigidly held at its perimeter in a stretched condition across a switch substrate (23). The key switches include metal snap domes (12) that have an elevated central region (212) forming a downwardly facing cavity (13) defined at its edge by a ridge (214) disposed above the switch contacts (21) that electrically engages multiple switch contacts in an annular contact zone (230).
Patent CA-2485077-C (CA)
Title: Method for reducing the content of an unsaturated amine in a mixture containing an amino nitrile, a diamine, a dinitrile or mixtures thereof
Inventor: MAIXNER STEFAN
IPC: C07C253/34
Filed: 2003-05-21
Granted: 2010-05-18
Abstract: The invention relates to a method for reducing the content of an aliphatic, monounsaturated amine (IV) in a mixture (V) containing an aminonitrile (I) or a diamine (II) or a dinitrile (III) or mixtures thereof and amine (IV), whereby: a) mixture (V) is reacted with an anionic nucleophile (VI) in a quantity ranging from 0.01 to 10 mols per mol of amine (IV) in mixture (V) at a temperature ranging from 50 to 200 ~C while obtaining mixture (VII), and; b) amino nitrile (I) or diamine (II) or dinitrile (III) or mixtures thereof are removed by distillation from mixture (VII) at a temperature ranging from 50 to 200 ~C and under a pressure ranging from 0.1 to 100 kPa while obtaining a bottom product (VIII). The inventive method is characterized in that: c) an amino nitrile (I) or diamine (II) or dinitrile (III) or mixtures thereof are removed by distillation from bottom product (VIII) at a temperature which is lower than that selected in step b).
Patent CA-2487566-C (CA)
Title: Inhibitors of adp-ribosyl transferases, cyclases, and hydrolases
Inventor: SAUVE ANTHONY A
IPC: C07H19/04
Filed: 2003-05-30
Granted: 2012-08-07
Abstract: The present invention provides compounds having the formula: (I); Also provided are pro-drug compounds of the formula: (II); The invention also provides pharmaceutical compositions containing the above compounds, methods of using the above compounds as pharmaceuticals, and processes for preparing the above compounds. Methods for inhibiting an ADP-ribosyl transferase, ADP-ribosyl cyclase, ADP-ribosyl hydrolase, or NAD-dependent deacetylase enzyme using the above compounds, and methods for treating a disease or condition associated with an ADP-ribosyl transferase, ADP- 'ribosyl cyclase, ADP-ribosyl hydrolase, or NAD-dependent deacetylase enzyme in a subject using the above compounds are also provided.
Patent CA-2489982-C (CA)
Inventor: STREEKSTRA HUGO
IPC: A23L1/30
Filed: 2003-06-20
Granted: 2019-09-10
Abstract: la présente invention concerne un procédé d'obtention d'huile microbienne consistant à cultiver un micro-organisme en deux étapes de fermentation. Au cours de la dernière étape précédant la fin de la fermentation, la source de carbone est: consommée par les micro-organismes à un rythme plus rapide que son rythme d'alimentation dans le milieu ; ajoutée à un taux = 0.30 M carbone/kg milieu; ou bien est limitée par la croissance des micro-organismes. Comme la source de carbone est limitée, les micro-organismes métabolisent de préférence des graisses ou des lipides autres que l'acide arachidonique (ARA), ce qui augmente la teneur des cellules en ARA. Au moyen d'hexane comme solvant, on extrait ensuite une huile microbienne des micro-organismes qui contient au moins 50 % d'ARA et au moins 90 % de triglycérides.
Patent CA-2497869-C (CA)
Title: Generateur d'aerosol et son procede d'utilisation
Inventor: NGUYEN TUNG T
IPC: A61M15/00
Filed: 2003-09-05
Granted: 2013-06-04
Abstract: L'invention concerne un générateur d'aérosol qui génère un aérosol présentant une taille de particules souhaitée en faisant passer un liquide à travers un passage d'écoulement chauffé afin de convertir le liquide en vapeur. Le passage d'écoulement comprend une partie de sortie qui règle la vitesse de sortie de la vapeur et qui produit un aérosol présentant une taille de particules souhaitée. Le générateur d'aérosol selon l'invention peut être intégré dans un inhalateur manuel et le liquide peut contenir un médicament qui est administré à une partie ciblée du poumon à l'aide de l'inhalateur.
Patent CA-2501551-C (CA)
Inventor: MATHER PATRICK T
IPC: A61K6/90
Filed: 2003-10-10
Granted: 2012-12-11
Abstract: L'invention concerne un polycyclooctène réticulé chimiquement présentant de remarquables propriétés de rétablissement de forme et un procédé de synthèse de ce composé par polymérisation méthathèse avec ouverture du cycle d'un noyau d'un cyclooctène au moyen d'un catalyseur de Grubb modifié par dihydroimidazolylidène. Après durcissement au moyen de peroxyde de dicumyle, les produits en polycyclooctène peuvent prendre une forme donnée, garder la mémoire de cette forme, recevoir une nouvelle forme, la forme d'origine pouvant être rétablie par un ajustement approprié de la température. On a établi l'existence d'une dépendance entre les caractéristiques de mémoire de forme et le degré de réticulation. Outre le polycyclooctène, des mélanges de ce composé avec d'autres matériaux tels que du butadiène-styrène, acétate de vinyle éthylène, caoutchoucs en polyuréthane et charges inorganiques peuvent être utilisés pour l'obtention de produits réticulés chimiquement possédant des propriétés de mémoire de forme remarquables et adaptées aux besoins.
Patent CA-2502393-C (CA)
Title: Method and device for the detection of the presence, and the real-time analysis of, chemical and/or biological substances in the atmosphere
Inventor: LANCELIN HENRI
IPC: G01N21/72
Filed: 2003-10-09
Granted: 2011-11-22
Abstract: The invention relates to a device for analysing a gaseous composition by means of flame spectrophotometry, which can be used to identify a current test spectrum and which is based on a knowledge acquisition and diagnostic method. The inventive method comprises the following steps: the main component analysis of reduced data from the current spectrum; the creation of a matrix representing the set of projected spectra of the set of active elements; the classification of the set of projected spectra of the set of active elements into current groups; the evaluation of the membership potential of the current spectrum in relation to all of the current groups; the membership of the current spectrum to one of the current groups of the set of active elements if the membership potential to said group of said current spectrum is greater than a pre-determined threshold; the triggering of the alarm if one of the current groups of the set of active elements presents an appearance frequency for different elements of the group which is greater than a pre-determined threshold; and remote rejection of the current spectrum and agglomeration to one of the groups being formed if said current spectrum departs sufficiently from the existing forms in order to form part of a new group.
Patent CA-2502965-C (CA)
Inventor: BARTHOLOMAEUS JOHANNES
IPC: A61K47/00
Filed: 2003-10-24
Granted: 2016-04-12
Abstract: The invention relates to a dosage form that is safeguarded from abuse. In addition to one or more active substances that could be subject to abuse, said form comprises two or more of the following constituents (a)-(d): (a) at least one substance that irritates the nasal and/or pharyngeal region; (b) at least one agent that increases viscosity, which forms a gel in an extract that is obtained from the dosage form with the aid of a required minimum quantity of an aqueous liquid, whereby the gel can still be visibly differentiated after being introduced into an additional quantity of an aqueous liquid, (c) at least one antagonist for the active substance or substances that could be subject to abuse, (d) at least one emetic.
Patent CA-2512885-C (CA)
Inventor: GATI UZI
IPC: B23B27/06
Filed: 2004-02-04
Granted: 2009-06-23
Abstract: A cutting insert for grooving operations having a forward main cutting edge and two opposing side cutting edges extending rearwardly from the main cutting edge on opposing sides of a center line of the cutting insert, wherein each side cutting edge has a generally serrated form in a top view of the cutting insert.
Patent CA-2513202-C (CA)
Inventor: ANVARI MEHRAN
IPC: B25J13/00
Filed: 2005-07-25
Granted: 2015-03-31
Abstract: A robotic system and method for performing surgical operations using robotic arms which can also be remotely controlled by at least one operator console. The system and method comprise a track system for mounting to a patient support table, a plurality of base stations for operatively coupling each of the robotic arms to the track system. The system and method can also have a control unit for coupling to at least two of the base stations and configured for dynamically connecting operative remote control between the coupled base stations and a first operator console of the at least one operator console.
Patent CA-2527340-C (CA)
Inventor: RICHARDSON JOSEPH THOMAS
IPC: A47F3/00
Filed: 2005-11-18
Granted: 2010-06-22
Abstract: Une pluralité de présentoirs modulaires distincts sont installés de manière interchangeable sur une tablette d'une structure d'armoire correspondante et disposés pour constituer des panneaux incurvés de façon concave pour la présentation d'agencements choisis d'échantillons éclairés de circuits à puces, d'écran vidéo interactif et de porte-brochures. La structure est dotée d'un système intégré de distribution d'eau à gicleurs et peut comporter un mécanisme en deux pièces pour le montage de circuits à puces facilitant le changement d'échantillons de ces circuits à puces.
Patent CA-2534721-C (CA)
Title: Cutting edge honing process
Inventor: ENGIN SERAFETTIN
IPC: B24C1/02
Filed: 2006-01-31
Granted: 2012-01-17
Abstract: A method of honing a cutting edge of a rotary cutting tool comprising inserting the cutting tool into a liquid bath having an abrasive media therein such that at least the cutting edges are immersed, and providing a relative displacement of the cutting tool and the liquid bath such that the abrasive media flows over the cutting edges.
Patent CA-2535157-C (CA)
Inventor: ROY SUMANTRA
IPC: H04L12/26
Filed: 2006-02-02
Granted: 2013-01-22
Abstract: In one embodiment, the present invention is a method and apparatus for monitoring virtual private networks (VPNs) supported on a multiprotocol label switching (MPLS) backbone network. In one embodiment, a method for remote monitoring of a VPN supported on an MPLS backbone network includes capturing traffic to and/or from the virtual private network (e.g., via a network probe) and analyzing the captured traffic in accordance with one or more service objectives. In another embodiment, the present invention involves remotely simulating network conditions in a virtual private network, for example by sending test patterns to a shared customer edge router connected to the virtual private network, forwarding the test patterns, via the shared customer edge router, to the MPLS backbone network, and forwarding the test patterns over the MPLS backbone network to a discrete customer edge router associated with the virtual private network.
Patent CA-2535990-C (CA)
Title: Fire fighting bucket suspendable from aircraft
Inventor: HALL GEOFF
IPC: A62C3/02
Filed: 2003-09-04
Granted: 2010-06-08
Abstract: Firefighting bucket (11) suspended from an aircraft by lines (15), has open top (12A) and a valve at base (13). The valve is attachable to the aircraft by remotely actuatable line (16) and independent movement of lines (15-16) may utilise the weight of the water to facilitate opening and closing of the valve. Dynamic sensing of a bucket attribute, e.g. weight, enables bucket (11) to be filled or discharged by a pre-determined volume by the pilot. Chemical fire retardant may be added by entraining it with water discharging from the valve.
Patent CA-2538778-C (CA)
Inventor: MILLER CARY JAMES
IPC: C12M1/34
Filed: 2004-09-09
Granted: 2013-08-27
Abstract: An apparatus and method for sealing a fluid sample collection device, comprising: loading a fluid sample collection device with a fluid sample, said device comprising a housing having at least one substantially planar surface that includes an orifice in fluid communication with an internal fluid sample holding chamber which terminates at an internal capillary stop; and slidably moving a sealing element over at least a portion of said substantially planar surface in a way that displaces any excess fluid sample away from the orifice, seals the fluid sample within said holding chamber, and inhibits the fluid sample from prematurely breaking through the internal capillary stop.
Patent CA-2540145-C (CA)
Title: Dual tensioning health support
Inventor: GOODRICH KELLIE M
IPC: A61F5/01
Filed: 2004-09-23
Granted: 2012-11-27
Abstract: A dual tensioning health support includes a support layer adapted to be at least partially wrapped about a body part; first and second elongated securing straps extending from opposite sides of the support layer adjacent a first common side of the support layer such that they can be simultaneously pulled away from each other in opposite directions without substantial twisting of the support layer; a first securing device for securing a distal end of the first elongated securing strap to the support layer after the first elongated securing strap has been wrapped at least partially about the body part; and a second securing device for securing a distal end of the second elongated securing strap to the support layer after the second elongated securing strap has been wrapped at least partially about the body part.
Patent CA-2543257-C (CA)
Inventor: KHAN SHAHARYAR
IPC: C12Q1/68
Filed: 2004-10-25
Granted: 2013-12-31
Abstract: Methods and compositions for delivering polynucleotides are provided. One embodiment provides a non-viral vector comprising a recombinant polynucleotide-binding protein comprising a protein transduction domain operably linked to a targeting signal. Methods for modifying the genome of non-nuclear organelles are also provided.
Patent CA-2543754-C (CA)
Inventor: WHAM ROBERT HARTZELL
IPC: A61B18/12
Filed: 2003-11-21
Granted: 2013-10-15
Abstract: An automatic control system for an electrosurgical generator is herein disclosed. The automatic control system includes voltage and current sensing circuits, a processing circuit, an output determining circuit, and a control circuit. Samples of the voltage and current outputs are supplied to the processing circuit and the output determining circuit to generate an output signal. The output signal is compared to a reference signal to generate a feedback signal for controlling a drive circuit.
Patent CA-2551011-C (CA)
Title: Plant activation of insect toxin
Inventor: ABAD ANDRE
IPC: C07K14/325
Filed: 2004-12-20
Granted: 2013-04-16
Abstract: Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.
Patent CA-2562757-C (CA)
Inventor: SANDOVAL RUBEN
IPC: F21S8/00
Filed: 2006-10-06
Granted: 2010-09-21
Abstract: A lighting fixture where the lighting fixture uses inductive lighting technology or self ballasting lighting elements with one or a plethora of efficient light elements. The lighting fixture is used where high bay or low bay lighting may be used, but incorporates multiple light sources to provide an equivalent light intensity. The multiple light sources can be inductive or multiple fluorescent, LED or other efficient light sources to provide a less expensive cost of operation and installation. The higher efficiency lights could be standard socket type fluorescent or inductive light bulbs that are easily available. The higher efficiency lights will also create less heat that will further reduce the air conditioning or cooling costs for the building. An integrated ballast box with reflector dome retainer is also shown for use with inductive or other lighting that further includes a retaining mechanism for the dome.
Patent CA-2567206-C (CA)
Inventor: JANZEN MARTIN
IPC: B27B31/04
Filed: 2006-11-03
Granted: 2012-04-10
Abstract: A log profiler for sawing surfaces into and along the length of a log may be characterized as including a saw carriage selectively translatable along a track, a pair of log holders on the track for holding the log suspended over and along the track and adapted to selectively rotate the log about its long axis, a linear double-acting saw blade mounted on a blade carriage, the blade translatable linearly along the blade carriage relative to both the blade carriage and saw carriage, the blade carriage selectively rotatable and selectively elevatable relative to the saw carriage.