Patent SG-11201805788W-A (SG)
Title: Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation
Inventor: NARASIMHAN RANGACHARI
IPC: A61M15/00
Filed: 2017-02-01
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 1111111101111011101010111110101111101110111001100111110111011111101111011111 International Bureau 0.. .... .. ...... ... (10) International Publication Number (43) International Publication Date WO 2017/136421 Al 10 August 2017(10.08.2017) WIPO I PCT (51) International Patent Classification: (74) Agents: MATA, David et al.; Wilson Sonsini Goodrich & A61K 31/4458 (2006.01) A61B 5/046 (2006.01) Rosati, 650 Page Mill Road, Palo Alto, California 94304 A61B 5/0464 (2006.01) A61M 15/00 (2006.01) (US). (21) International Application Number: (81) Designated States (unless otherwise indicated, for every PCT/US2017/016018 kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (22) International Filing Date: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, 1 February 2017 (01.02.2017) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (25) Filing Language: English HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, (26) Publication Language: English MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (30) Priority Data: NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, 62/289,473 1 February 2016 (01.02.2016) US RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (71) Applicant: INCARDA THERAPEUTICS, INC. ZA, ZM, ZW. [US/US]; 150 North Hill Drive #24, Brisbane, California 94005 (US). (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (72) Inventors: NARASIMHAN, Rangachari; 20661 Oak GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, Creek Lane, Saratoga, California 95070 (US). BE- TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, LARDINELLI, Luiz; 205 Manzanita Avenue, Palo Alto, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, California 94306 (US). SCHULER, Carlos A.; 21866 DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, Wilson Court, Cupertino, California 95014 (US). LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, [Continued on next page] (54) Title: COMBINING ELECTRONIC MONITORING WITH INHALED PHARMACOLOGICAL THERAPY TO MANAGE CARDIAC ARRHYTHMIAS INCLUDING ATRIAL FIBRILLATION (57) : Disclosed herein are methods of incarda - Flecainide Site Cart ® Oven treating cardiac arrhythmia with electronic monit- oring in a timely manner. Also disclosed herein are systems for electronic monitoring of cardiac arrhythmia. 2337623, IV CBDCNM, IT 400 E 200 el 0 600 — F - -6 -I---- - - - -,- - , ' , - - - ---- ...• -r 1 J. 1 Al II EM 111111 Concentra t i 4 1.. rn CD 0 0 0 0 0 0 I CCBCTC, IT CDGDAE, IT _, — 1 - a 100 200 300 0 100 200 300 71' Time after first dose (min) M 1-1 IN FIG. 1 ,-1 © ei C WO 2017/136421 Al 1#110H011111 1E1111ME3011110110011110EMEHOIS SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, Published: GW, KM, ML, MR, NE, SN, TD, TG). — with international search report (Art. 21(3)) Declarations under Rule 4.17: — as to applicant's entitlement to a patent (Rule 4.17(ii)) apply for and be granted