baber/WOPTO huggingface dataset:
Patent CA-2445329-A1 (CA)
Title: 20-hydroxyeicosatetraenoic acid production inhibitors
Inventor: MIYATA NORIYUKI
IPC: C07D207/20
Filed: 2002-04-26
Abstract: A hydroxyformamidine compound represented by the following formula or a pharmaceutically acceptable salt thereof.   (see above formula) [wherein R1 represents a substituted morpholino group, a substituted piperidino group, a piperazin-1-yl group, a substituted piperazin-1-yl group, a thiomorpholin-1-yl group, a perhydroazepin-1-yl group, a perhydroazocin-1-yl group, a tetrahydropyridin-1-yl group, a pyrrolin-1-yl group, etc.; X  represents a nitrogen atom or a group represented by CR5; and R2 to R5 are the same or different and each represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkoxy group, a trifluoromethyl group or a halogen atom.]     There is provided a drug which inhibits an enzyme producing 20-HETE participating in a contracting or dilating action for microvessels and an inducing action for cell proliferation in main organs such as kidney and cerebrovascular vessels.
Patent CA-2448975-A1 (CA)
Inventor: HULETSKY ANN
IPC: C12Q1/689
Filed: 2002-06-04
Abstract: L'invention porte sur de nouvelles séquences de jonction de l'extrémité droite de SCCmec servant à détecter les Staphyloccocus aureus résistant à la méthicilline (MRSA), et sur l'utilisation de ces séquences d'ADN à des fins de diagnostic.
Patent CA-2450379-A1 (CA)
Inventor: HAMPTON GARRET M
IPC: C12Q1/68
Filed: 2002-06-10
Abstract: L'invention concerne des méthodes, des trousses de diagnostic, et des algorithmes permettant d'obtenir des signatures moléculaires de cellules en fonction de leurs profils d'expression génique. L'invention concerne également des dispositifs permettant d'analyser une signature moléculaire d'échantillons inconnus.
Patent CA-2454202-A1 (CA)
Inventor: BELOTSERKOVASKY EDWARD
IPC: G01N21/57
Filed: 2002-07-16
Abstract: L'invention concerne un capteur de brillant servant à mesurer optiquement le brillant d'une surface et à compenser la formation de poussière sur le capteur. Le capteur de brillant comprend une source lumineuse et un premier collimateur servant à recevoir de l'énergie lumineuse provenant de la source lumineuse, à former un faisceau lumineux à l'intérieur de ce collimateur, et à émettre un faisceau lumineux collimaté à partir de ce collimateur. Un premier détecteur est situé à l'intérieur du premier collimateur pour développer un signal de référence, et un diviseur de faisceau, adjacent au premier collimateur sert à diviser le faisceau collimaté en un premier faisceau et en un second faisceau, le second faisceau étant reçu par un dispositif de réflexion. Un premier miroir est conçu pour réfléchir le premier faisceau sur une surface à mesurer par le biais de la première fenêtre, et étant également conçu pour recevoir le second faisceau réfléchi à partir du dispositif de réflexion. Un second miroir reçoit le premier faisceau réfléchi à partir de la surface à mesurer, par le biais d'une seconde fenêtre, et le second faisceau étant réfléchi par le premier miroir par le biais de la première fenêtre et de la seconde fenêtre, et réfléchit le second faisceau sur le dispositif de réflexion. Un second collimateur est positionné pour recevoir le premier faisceau réfléchi à partir du second miroir comprenant un second détecteur de lumière, pour dériver un signal de détection représentant une mesure du brillant de la surface. Un troisième détecteur est disposé de manière adjacente au dispositif de réflexion, et est conçu pour recevoir le second faisceau et dériver un signal de compensation représentant la formation de poussière sur la première fenêtre et sur la seconde fenêtre, et un dispositif de correction recevant le signal de référence, le signal de détection et le signal de compensation développant à l'intérieur de ce détecteur un signal de brillant corrigé.
Patent CA-2459254-A1 (CA)
Title: Systems and methods for processing signals from an interferometer by an ultrasound console
Inventor: CROWLEY ROBERT J
IPC: A61B8/00
Filed: 2002-10-09
Abstract: An imaging system comprises an interferometer and an ultrasound console that processes signals from the interferometer into an image for display. The interferometer may include one or more multi-element photo detectors with a plurality of parallel outputs. A parallel to serial converter is provided between the parallel output of the interferometer and the input of the ultrasound console, to convert the signals provided on the parallel outputs into a serial signal for analysis by the ultrasound console. The interferometer may be selectively coupled to the ultrasound console and the system may further comprise an ultrasound device that may also be selectively coupled to the console, offering a user the option of using either the interferometer or the ultrasound device. The ultrasound console may also include two inputs, one for the interferometer and the other for the ultrasound device. The interferometer and the ultrasound device may both be carried by catheters for insertion into internal body cavities, such as blood vessels. Imaging methods are also disclosed.
Patent CA-2464327-A1 (CA)
Inventor: PICHA FRANTISEK
IPC: A61P39/00
Filed: 2002-10-15
Abstract: The invention relates to a compound or composition comprising N-formyl paroxetine of formula (1) and 0 to 99.97% of a paroxetine compound, based on the combined weight of said N~-formyl paroxetine and said paroxetine compoun d, to a pharmaceutical composition, for treating a selective serotonin reuptake inhibitor-treatable disease or condition, comprising an effective amount of a paroxetine agent and at least one pharmaceutically acceptable excipient, wherein said paroxetine agent comprises of an N-formyl paroxetine compound o f formula (1) and optionally a paroxetine compound, and to a process for producing a paroxetine compound which comprises treating an N-formyl paroxetine compound of formula (1) with a de-formylation agent, to a compoun d having the formula (2), to a process for determining the stability or purity of a paroxetine substance or composition, which comprises assaying a paroxetine substance or composition for the presence of an N-formyl paroxeti ne compound of formula (1), and to a process assaying the quality of paroxetine , which comprises forming a production lot of paroxetine pharmaceutical solid dosage forms wherein each dosage form comprises paroxetine or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable exipient; removing a sample ofsaid paroxetine pharmaceutical soli d dosage forms from said production lot; assaying said sample for the presence and/or amount of N-formyl paroxetine; and selling or releasing said producti on lot if said sample passes said assay with respect to the presence or amount of N-formyl paroxetine.
Patent CA-2466031-A1 (CA)
Title: An ultrasonic clamp coagulator apparatus having an improved clamping end-effector
Inventor: WAMPLER SCOTT
IPC: A61B17/32
Filed: 2002-11-07
Abstract: An ultrasonic surgical clamp coagulator apparatus (10) is configured to effe ct cutting, coagulation and clamping of tissue by cooperation of a clamping mechanism of the apparatus with an associated ultrasonic end-effector (20). The clamping mechanism includes a pivotal clamp arm (24), which cooperates with the end-effector (20) for gripping tissue. The clamp arm (24) is provid ed with a clamp tissue pad that has at least one raised portion (28) to achieve the desired cutting and coagulation effect on the tissue.
Patent CA-2467213-A1 (CA)
Inventor: COGLEY PAUL A
IPC: B65D81/34
Filed: 2004-05-13
Abstract: A susceptor tray has a susceptor surface of a platform positioned above a downwardly extending portion that has sidewall functions and that traps heated vapor within an open surface defined by the susceptor tray. A kit of the susceptor tray and a dough-containing food product has a storage mode which permits the food product to be stored within the open volume and out of contact with the susceptor surface. The extending portion preferably includes apertures to permit controlled dissipation of heated vapor from out of the open volume during cooking within a microwave oven.
Patent CA-2471278-A1 (CA)
Inventor: SOLOMON BERNARD J
IPC: G06F3/0484
Filed: 2002-12-06
Abstract: The processing system (10) is disclosed which uses a user interface (12) to interact with the search and control engine (16) and the display engine (18).  The search and control engine (16) operates on a data set (14) to identify specific elements within a directory structure. Display engine (18) compiles the identified elements in a tree table (20) to format a display (22) associated with the directory structure. Pruning indicator (34) and a sibling pruning indicator (36) are used in the display (22) to inform the user that intermediate directory structures and sibling elements have been omitted from the display in order to show the identified elements in a truncated context within the complex directory structure.
Patent CA-2471394-A1 (CA)
Inventor: VUYK ADRIAN JR
IPC: E21B23/04
Filed: 2004-06-18
Abstract: The present invention provides an improved hydraulic overshot tool. The overshot tool mechanically engages a cylindrical body downhole attempting to be retrieved. In the event retrieval is unsuccessful, the overshot tool may be hydraulically released from the cylindrical body. The release function employs a pressure differential within the overshot tool, but without necessity of a nozzle within the bore of the tool.
Patent CA-2472166-A1 (CA)
Inventor: HUGHES PAUL
IPC: F16J15/40
Filed: 2002-12-24
Abstract: L'invention concerne un adaptateur pouvant être utilisé avec un équipement fluidique rotatif, destiné à protéger les joints d'étanchéité mécaniques et/ou les matériaux de remplissage adjacents à une cavité (18) d'étanchéité de l'équipement. L'adaptateur comprend un corps annulaire (30) présentant un alésage central (32) adapté pour recevoir une tige (12) de l'équipement. Lorsqu'il est utilisé avec des joints d'étanchéité mécaniques, l'adaptateur peut être reçu dans la cavité (18) à l'entrée de celle-ci et comprend une partie dont la surface vient en contact avec une surface complémentaire du joint d'étanchéité. Lorsqu'il est utilisé avec un matériau de remplissage, l'adaptateur est inséré dans la cavité et définit une extension extérieure dans laquelle peut être reçu le matériau de remplissage. L'alésage définit deux parties, l'une (52) près de la tige, et l'autre (54) évasée vers l'extérieur de ladite partie vers l'extrémité extérieure de l'adaptateur. Chaque partie de l'alésage présente une rainure (56, 58) en spirale, ladite rainure servant à rediriger les matières contaminantes contenues dans les fluides entourant la tige loin de la cavité d'étanchéité.
Patent CA-2472486-A1 (CA)
Inventor: HEIKAUS GERD
IPC: B65H19/30
Filed: 2002-11-28
Abstract: A supplying device for film cores (12) for a film roll winding machine, in which the film rolls (12) are vertically arranged, comprises a feeding device (10) for horizontally feeding film cores (12). The feeding device (10) is connected to a raising device (32) that serves to transfer a film core (12) out of a horizontal position and into a vertical position. The film core (12) is removed from the raising device (32) by means of a transfer device (36) and is transferred to the film roll winding machine.
Patent CA-2473702-A1 (CA)
Inventor: BOULERNE PHILIPPE
IPC: G01R23/00
Filed: 2004-07-15
Abstract: The present invention discloses a load-pull slide-screw tuner consisting of a radio-frequency (RF) or microwave slotted airline (slab-line) containing a single corrugated RF slug, said corrugated RF slug being controlled horizontally and vertically by remote electric control, allowing the creation of impedances which are distributed over and cover the entire Smith chart, from perfect transparency to high reflection factors. The corrugation structure of the RF slug of this invention provides the slide-screw tuner, with a single RF slug, the same electromagnetic performances than double slug slide-screw tuner, i.e. same frequency bandwidth of use and equivalent high gamma performances, at a much lower cost of manufacturing.
Patent CA-2475329-A1 (CA)
Inventor: LAVALLIE EDWARD R
IPC: A61P31/04
Filed: 2003-02-05
Abstract: La présente invention concerne des protéines d'aggrécanase tronquées et des séquences de nucléotides codant pour celles-ci, ainsi que des procédés pour les produire. L'invention a également pour objet des aggrécanases qui comportent des mutations d'acides aminés et conduisent à une meilleure stabilité et des niveaux d'expression supérieurs en comparaison avec les aggrécanases de type sauvage ou natives. Les aggrécanases de l'invention sont particulièrement utiles pour mettre au point des compositions destinées au traitement de maladies telles que l'ostéoporose. L'invention concerne également des procédés pour mettre au point des inhibiteurs des enzymes d'aggrécanases et des anticorps anti-enzymes d'aggrécanases pour traiter les états pathologiques se caractérisant par la dégradation de l'aggrécane.
Patent CA-2476552-A1 (CA)
Inventor: KEANE JOHN
IPC: H04L12/46
Filed: 2003-02-07
Abstract: Methods and systems are provided for resolving an addressing conflict between a first processor (1540) in a first network (1180) and a second processor (1560) in a second network (1170). When an addressing conflict is detected between a first address of the first processor (1540) and a second processor (1560), tunnel information is removed from one or more packets received from the first processor (1540). Based on the removed tunnel information, the packets are associated with the detected addressing conflict and a translated address is determined. Based on the translated address, the packets are then forwarded.
Patent CA-2477384-A1 (CA)
Inventor: ANDREPONT JOHN STEPHEN
IPC: F02C3/24
Filed: 2002-02-25
Abstract: L'invention concerne un combustible à base d'hydrocarbure liquide pour un groupe moteur, vaporisé contre un fluide d'échange thermique, refroidissant ainsi le fluide. Un circuit (32) de recirculation permet au fluide refroidi d'être redirigé en arrière pour être à nouveau refroidi lorsque désiré. Le fluide refroidi est utilisé pour refroidir l'air d'entrée d'une turbine (16) à combustion. Une partie du fluide refroidi est périodiquement dirigée vers le fond d'un réservoir stratifié (12), d'où le fluide peut être retiré lorsque le besoin ou la valeur de refroidissement de l'air d'entrée est plus élevé. Le fluide est réchauffé tandis qu'il refroidit l'air d'entrée, et peut être utilisé pour vaporiser du combustible supplémentaire, ou redirigé vers la partie supérieure du réservoir stratifié (12).
Patent CA-2482139-A1 (CA)
Title: System and method for laying floor coverings
Inventor: SIEBER MARCO
IPC: C09J7/20
Filed: 2004-09-22
Abstract: The invention relates to a system and a method for laying floor coverings, in particular wall-to-wall carpet, on floors, in particular stairs, whereby the system has a pressure-sensitive adhesive tape and an adhesive mass, whereby the pressure-sensitive adhesive tape has a carrier layer that is coated with an adhesive coating on a top surface that faces the floor covering and on a bottom surface that faces the floor or the stair. The adhesive mass can be applied at least partially for gluing a backing of the floor covering, in particular in areas with particular shear and/or peel stresses on the floor covering.
Patent CA-2482199-A1 (CA)
Title: Oral rehydration composition
Inventor: SACK DAVID A
IPC: A61K33/14
Filed: 2003-04-08
Abstract: A rehydration composition and oral delivery system is provided that allows for enhanced functional ingredient delivery when ingested orally as a water based solution. The rehydration composition comprises a low fiber colloidal hydrolyzed rice carbohydrate ingredient having, on a dry weight basis, less than 0.1% fiber and between 0.5% and 1.0% protein and between 0-0.5% and 1.0%  fat, and having a dextrose equivalency (DE) value within the approximate range of 20 - 30 (commonly DE 25), and electrolytes such as sodium, potassium, citrate, and/or bicarbonate. The rehydration composition, which is concentrated or dried, becomes an oral rehydration solution (ORS) when mixed with water for oral consumption. The rehydration composition, when mixed with active ingredients such as vaccines, drugs, amino acids, mineral salts, vitamins, nutraceuticals, probiotics, prebiotics, flavors, or nutritive or non-nutritive sweeteners, is referred to as an oral delivery system. This oral delivery system may then be further diluted in a water base to produce an oral delivery solution that is suitable for oral ingestion by a user.
Patent CA-2484051-A1 (CA)
Inventor: DELUCA FRANK
IPC: F02M61/18
Filed: 2004-10-06
Abstract: An annular notch is provided in the body seat associated with the nozzle valve of an ALCO-type diesel injector. The notch extends from (i) an upper edge that is on the seat and is above the imaginary edge that would have been the sac inlet edge had the notch not been provided to (ii) a lower edge below such imaginary edge. The notch has a lowest wall that, at least at the portion of its length where such lowest wall approaches such lower edge, has a given angle-to-vertical of less than 60°.
Patent CA-2485924-A1 (CA)
Title: Controlling solids circulation in a gas-solids reaction system
Inventor: COUTE NICOLAS P
IPC: B01J8/18
Filed: 2003-05-02
Abstract: This invention provides a method for controlling solids circulation in a gas - solids reaction system. The method entails aerating solid particles in a standpipe. Aeration fluid is injected into the standpipe at the appropriate location to increase apparent density of the solid particles.
Patent CA-2486215-A1 (CA)
Inventor: ARRINGTON KENNETH L
IPC: A61P37/02
Filed: 2003-06-12
Abstract: La présente invention concerne des composés de dihydropyrazole utiles pour traiter les troubles associés à l'activité de kinésine KSP et pour inhiber la kinésine KSP. L'invention concerne aussi des compositions qui comprennent ces composés et des procédés pour les utiliser dans le traitement du cancer affectant les mammifères.
Patent CA-2494046-A1 (CA)
Inventor: SHARMA RAJAN
IPC: G06F12/12
Filed: 2003-07-31
Abstract: A cache controller (300) includes potential replacement list (320), each entry of the list containing an aging counter (335) and a pointer (325) indicating an entry in a cache (302) that may potentially be replaced. When a hit in the list, the pointer is taken out of the list and replaced by a new random pointer from a random value generator (360). In the same manner upon a cache miss, the least recently used pointer (325) determined by the aging counters (335) is used for replacing an entry in the cache (302) and is replaced itself by a random value.
Patent CA-2497144-A1 (CA)
Inventor: SEIDITA THOMAS M
IPC: B65D41/34
Filed: 2003-09-10
Abstract: A container assembly (10) includes a container (12) that has an externally threaded finish portion and a retention structure (18) for preventing upward movement of a tamper evident band (38). The assembly (10) further includes a closure (28) having a body portion (32) of a base (34) and an internally threaded downwardly depending sidewall portion (36) that is sized and shaped to screw onto the container finish portion. The closure further includes a tamper evident band (38) that is frangibly connected to the sidewall portion (36) and that includes a main band portion (42) and a J-hook retention member (44). The retention member (44) includes a plurality of pleated retaining elements (46) for engaging the retention structure (18). At least one of the pleated retaining elements (46) is adapted to engage the container (12) so as to resist rotation with respect to the container. Separation of the tamper evident band (38) from the body portion (32) is better assured when the closure (28) is unscrewed from the container (12).
Patent CA-2499259-A1 (CA)
Inventor: AXEN NIKLAS
IPC: A61L27/10
Filed: 2003-09-25
Abstract: The present invention pertains to injectable heat generating biocompatible ceramic compositions based on hydraulic calcium aluminate, which can be used for therapeutic treatment in vivo, such as tumour treatment, pain control, vascular treatment, drug activation etc, when curing in situ, and which form a biocompatible solid material that can be left in the body for prolonged periods of time without causing negative health effects. The present invention can also be used to restore the mechanical properties of the skeleton after cancerous diseases.
Patent CA-2501578-A1 (CA)
Inventor: LABRASH RICHARD
IPC: E06C5/00
Filed: 2001-04-23
Abstract: A ladder mounting mechanism is configured for mounting a ladder to a truck trailer. The truck trailer has at least one keeper member fixedly connected thereto. The ladder mounting mechanism includes a frame and at least one moveable locking member moveably connected to the frame. The frame is adapted to be fixedly connected to the ladder. The moveable locking member is adapted for movement relative to the frame between a ladder-secured position and a ladder-unsecured position. In the ladder-secured position, the locking member engages the keeper member in a manner for securing the ladder to the truck trailer. In the ladder-unsecured position, the locking member is disengaged from the keeper member.
Patent CA-2502552-A1 (CA)
Title: Anticorps monoclonaux humains anti-cd20
Inventor: PETERSEN JORGEN
IPC: A61K39/00
Filed: 2003-10-17
Abstract: L'invention concerne des anticorps monoclonaux humains isolés qui se lient à l'antigène CD20 humain et l'inhibent, ainsi que des compositions et des molécules apparentées à base de ces anticorps. Les anticorps humains selon l'invention peuvent être produits par un transfectome ou dans un animal transgénique non humain, par exemple une souris transgénique, capable de produire plusieurs isotypes d'anticorps monoclonaux humains en subissant une recombinaison V-D-J et une commutation isotypique. L'invention concerne également des compositions pharmaceutiques comprenant ces anticorps humains, des animaux transgéniques non humains et des hybridomes qui produisent ces anticorps humains, ainsi que des procédés thérapeutiques et diagnostiques pour l'utilisation de ces anticorps humains.
Patent CA-2503365-A1 (CA)
Inventor: DOYLE DAVID R
IPC: B65B13/06
Filed: 2003-09-30
Abstract: L'invention concerne des systèmes et des procédés pour fileter et alimenter une longueur de fil dans un montage de ficelage, pour retirer au moins une partie du fil du montage de ficelage de manière à tendre le fil autour d'un ou plusieurs objets, et pour extraire les déchets de fil du système. L'invention se rapporte également à un mécanisme d'alimentation et de tension comprenant une roue d'alimentation et de tension, un disque accumulateur, et un mécanisme de resserrement primaire pour enclencher par friction le fil sur la région de contact entre le resserrement et la roue d'alimentation et de tension, un système de commande présentant deux moteurs fonctionnant de manière indépendante, et des dispositifs de guidage de fil destinés à diriger et acheminer le fil à travers le mécanisme d'alimentation et de tension. L'invention concerne de plus un mécanisme de resserrement supplémentaire qui facilite le filetage du fil dans le mécanisme, un mécanisme de débourrage du fil destiné à extraire chaque déchet de fil du mécanisme et une série de dispositifs de détection en communication avec un système de commande destinés à séquencer et à commander les cycles de fonctionnement du système. Le mécanisme d'alimentation et de tension comprend également un cadre qui supporte de manière structurelle les ensembles principaux et se fixe à la machine de ficelage.