baber/WOPTO huggingface dataset:
Patent NO-170217-B (NO)
Title: Analogifremgangsmaate for fremstilling av en terapeutisk aktiv forbindelse
Inventor: KUSAMA TSUNEO
IPC: C07H13/06
Filed: 1988-02-26
Abstract: Disakkaridforbindelse med formel ( 1) :. alkyl som kan være substituert med en eller flere. 3 8. hydroksyl, Z er Cj_g alkylen, R er C3_12 cykloalkyl som kan være substituert med en eller flere hydroksyl,. Q er hydrogen, Calkyl, -CONH-CO0H eller -CH2<3H; er hydrogen eller ^^.- 20 al-ky1; nl er " eller et helt tall 1-20 og n2 og n3 er hver et helt tall fra 1-20; og Rer hydrogen, fosfono eller -CO(CH_2 ) mCOOH hvori m er 0 eller et helt tall 1-6;. med den betingelse at en kombinasjon, hvori R er fosfono,. R er hydrogen og R,,og Rhver er -COR , er utelukket.Disakkarid-forbindelsene har farmasoytisk anvendelse.Deres fremstilling er beskrevet.
Patent NO-178199-B (NO)
Inventor: DIRLAM JOHN P
IPC: A61K31/70
Filed: 1990-08-07
Abstract: An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Actinomadura sp. ATCC 53708. This novel antibiotic is useful as an anticoccidial in chickens, in the prevention or treatment of swine dysentery, and as a growth promotant in cattle and swine.
Patent NO-180040-B (NO)
Inventor: GONZALEZ JOSE MARIA LOPEZ
IPC: B65D33/16
Filed: 1993-11-16
Abstract: Sliding lock comprised of a tubular body (1) presenting a longitudinal slit (2) deliminted by facing and proximate edges and by means of which said tubular body is intended to press on the walls of the container (3) by coupling and sliding thereto, the slit ending at one of its extremities into a diverging sector (4) which facilitates the coupling of the tubular body to the container, by acting as a guide for the same. The tubular body may incorporate one or a plurality of peripheral ribs (6) which stiffend its structure and minimize its elastic deformability, as well as an incision (5) at its extremity corresponding to the divergence of its longitudinal in order to improve its deformability in this area during the coupling to the container. <IMAGE>
Patent YU-42404-B (YU)
Title: Process for obtaining 1-carbamoyl-3-(3,5-dichlorophenyl)-hydantione
Inventor: GROS G
IPC: A01N47/08
Filed: 1981-05-29
Abstract: 1. Process for the manufacture of N-substituted 1-carbamoyl-3-(3,5-dichlorophenyl)-hydantoins of the formula: <IMAGE>  (I)  in which R1=alkyl (C1-C4) or phenyl and R2=H or alkyl (C1-C4). 2. This process comprises two steps: a. reacting phosgene with 3-(3,5-dichlorophenyl)-hydantoin in an inert organic solvent medium, in the presence of an acid acceptor, in order to form 1-chlorocarbonyl-3-(3,5-dichlorophenyl)-hydantoin, and b. reacting the chlorocarbonyl formed with an amine HNR1R2 in an inert organic solvent, in the presence of an acid acceptor. 3. This process makes it possible to obtain the products I, which can be used as agricultural fungicides, with good yields.
Patent YU-42911-B (YU)
Title: Process for obtaining new 2-(4-(diphenyl-methyl)-1-piperaznyl)acetic acids
Inventor: BALTES EUGENE
IPC: A61K31/495
Filed: 1984-12-28
Abstract: New 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acids, their amides and their salts, processes for the preparation thereof and therapeutic compositions. These compounds have the formula   <IMAGE> wherein Y=-OH or -NH2; X and X'=H, halogen, alkoxy or trifluoromethyl; m=1 or 2 and n=1 or 2. The amides of the 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acids are prepared either by reacting a 1-(diphenylmethyl)-piperazine with an omegahaloacetamide, or by reacting an alkali metal salt of an omega-[4-(diphenylmethyl)-1-piperazinyl]-alkanol with a 2-haloacetamide, or yet by reacting ammonia with a halide or alkyl ester of a 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acid, whereas the 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acids are prepared by hydrolyzing the corresponding amide or lower alkyl ester. These compounds have in particular an antiallergic, spasmolytic and antihistaminic activity.
Patent RS-50906-B (RS)
Inventor: LENSING ANTHONIE
IPC: A61P9/10
Filed: 2002-11-07
Abstract: Upotreba doze od 2.5 mg pentasaharida metil O-(2-dezoksi-2-sulfoamino-6-O-sulfo- α-D-glukopiranozil)- (1→4)-O-(β-D-glukopiranozil uronska kiselina)- (l→4)-O-(2-dezoksi-2- sulfoamino-3, 6-di-O-sulfo-α-D-glukopiranozil)- (1→4)-O-(2-O-sulfo-α-L-idopiranozil uronska kiselina)- (1→4)-2-dezoksi-2-sulfoamino-6-O-sulfo-α-D-glukopiranozida ili njegove farmaceutski prihvatljive soli za dobijanje leka za lečenje akutnih koronarnih sindroma (ACS). Prijava sadrži još 2 patentna zahteva.
Patent ZA-792973-B (ZA)
Title: Method of producing hollow moulded members as well as device for performing the method
Inventor: WILLMERDING G
IPC: B29C39/26
Filed: 1979-06-15
Abstract: Production of hollow shaped bodies made of pourable and hardenable material, particularly polyurethane tires, in a mold cavity having a deformable membrane. The membrane is expanded to fill the mold cavity and expel air therein. Thereafter an amount of material required to produce the shaped body is introduced into the mold cavity and concomitantly the membrane is contracted to the form of the core. This minimizes air bubbles in the shaped body. A piston-cylinder unit movable with the inflow and outflow of liquid to the deformable membrane may be used to accurately control feed of polyurethane material to the mold cavity.
Patent ZA-826230-B (ZA)
Title: Active compound combination of kitasamycin and quinoxaline di-n-oxides
Inventor: SELLE PETER HENRY
IPC: A23K20/195
Filed: 1982-08-26
Abstract: 1. Active compound combination consisting of kitasamycin and 2-methyl-3-carboxamidoquinoxaline- -1,4-di-N-oxides of the general formula I  see diagramm : EP0073390,P9,F2  wherein R**1 represents hydrogen, lower alkyl, lower alkoxy radicals and chlorine, R**2 represents hydrogen or a straight-chain or branched alkyl radical which is optionally substituted by a hydroxyl, lower alkoxy, carboalkoxy, mono- or dialkylamino radical, R**3 can represent hydrogen and wherein R**3 furthermore can be identical to or different from R**2 and in the case where R**2 is hydrogen R**3 can also represent the cyclohexyl radical and wherein in the case where R**2 and R**3 denote alkyl these radicals, together with the amide nitrogen atom, can be a constituent of a 5- or 6-membered heterocyclic ring system.
Patent ZA-831905-B (ZA)
Title: Valve unit for a liquid container
Inventor: LEWINS JOHN DAVID
IPC: F16K1/30
Filed: 1983-03-18
Abstract: A valve unit fitted in the neck (26) of a liquid container (25) has a hollow plastics core element (1) supported within a metal housing which is assembled from two cup-shaped parts (12, 13) provided with flanges (14, 15) at their open ends which are welded together. The lower part (12) includes flow openings (19) and is adapted to support a flange (2) of the core element (1) while the upper part has a flange (20) which cooperates with a valve member (11) and is surrounded by a sleeve (23) which secures the unit in the neck (26) of the container.
Patent ZA-844771-B (ZA)
Title: (3-amino-1h-pyrazol-4-y1)(aryl)methanones
Inventor: DUSZA JOHN PAUL
IPC: A61K31/443
Filed: 1984-06-22
Abstract: 3-Amino-1H-pyrazol-4-yl) (aryl)methanones which are new compounds having utility as anxiolytic agents or intermediates for the preparation of aryl and heteroaryl-[7-(aryl and heteroaryl)pyrazolo[1,5-a]pyrimidin-3-y1] methanones which are therapeutic agents described in copending application Ser. No. 506,966, filed June 23, 1983.
Patent ZA-849615-B (ZA)
Title: Analgesic dibenz(b,f)oxepins,a process for their preparation and their use as medicaments
Inventor: ONG HELEN H
IPC: A61K31/335
Filed: 1984-12-11
Abstract: The present invention relates to dibenz[b,f],oxepins having the general formula 
<CHEM>
 wherein n is an odd integer 1-7 inclusive; R is -C02R1 or -CH2OR2 where R1 is H, C1-5 loweralkyl, aralkyl, 
<CHEM>
 R3 being C1-5 loweralkyl; X and Y are each independently hydrogen, halogen, trifluoromethyl, C1-5 loweralkoxy, C1-5 loweralkyl, C1-5 loweralkylthio, or hydroxy; and the dotted line (....) may be a bond or nothing, and to a method for their preparation. The compounds of the invention are useful as analgesic agents.
Patent ZA-862431-B (ZA)
Title: Apparatus for the automatic preparation of a beverage
Inventor: ALIESCH ROBERT
IPC: A47J31/40
Filed: 1986-04-02
Abstract: A machine, for the automatic preparation of a beverage which is extracted from a product contained in a cartridge, has at least one extraction mechanism and at least one assembly having a plurality of magazines for housing cartridges containing product to be extracted and for supplying those cartridges to a conveyor which supplies the cartridges from a magazine to a distributor which then supplies the cartridges to the extraction mechanism and which also removes cartridges from the extraction mechanism for discarding the used cartridge.
Patent ZA-863314-B (ZA)
Title: Pharmaceutical compositions containing hollow fine tubular drug delivery systems
Inventor: LUCCIO ROBERT COSMO DI
IPC: A61J3/07
Filed: 1986-05-02
Abstract: Pharmaceutical compositions are provided which contain hollow fine tube drug delivery systems. The compositions comprise a pharmaceutically suitable carrier, preferably in the form of a capsule, tablet, suspension, or suppository, and at least one drug delivery system which consists essentially of (1) a polymeric tube having a membrane outer sheath and a hollow core, and (2) at least one drug compound contained within the core, said system contained in the composition in an amount sufficient to deliver a therapeutic amount of the drug contained therein at a predetermined rate over a predetermined period of time. By varying the polymer, the permeability of the outer sheath, the drug, the drug concentration in the hollow core of the tube, the tube diameter, the tube length, the tube core diameter, and the sealing of the tube ends, a wide variety of drug therapeutic amounts, rates and dosing times can be achieved.
Patent ZA-911253-B (ZA)
Title: Process for preparing uracil derivatives
Inventor: BEDESCHI ANGELO
IPC: C07D239/54
Filed: 1991-02-20
Abstract: PCT No. PCT/EP91/00324 Sec. 371 Date Aug. 21, 1992 Sec. 102(e) Date Aug. 21, 1992 PCT Filed Feb. 21, 1991 PCT Pub. No. WO91/13064 PCT Pub. Date Sep. 5, 1991.The present invention relates to a novel process for preparing uracil derivatives useful as intermediates in the synthesis of uridines having antiviral or antitumor activity or useful as coadjuvants in antiviral therapy, characterized by converting a compound of the formula II into its mesylate derivative of the formula III which is the reduced to give the desired compound of the formula I:  (* CHEMICAL STRUCTURE *)  (* CHEMICAL STRUCTURE *)  in which R1 is H, halogen, alkyl, aryl or aralkyl.
Patent ZA-912932-B (ZA)
Title: Method and composition for treating psoriasis
Inventor: SMITH STEVEN A
IPC: A61K33/24
Filed: 1991-04-19
Abstract: Psoriasis molecules are treated by administering non-toxic pharmaceutically acceptable solutions (topically, orally or by I.V.) of a composition containing nickel with a bromide carrier.
Patent ZA-913344-B (ZA)
Title: Substituted indoles
Inventor: SALLMANN ALFRED
IPC: C07D209/18
Filed: 1991-05-04
Abstract: Novel trisubstituted indole compounds of formula   <IMAGE> (I) +TR <IMAGE>  wherein R is straight-chain C2-C4alk-1-en-1-yl, and their salts can be used as pharmaceutical active ingredients and can be manufactured in a manner known per se.
Patent ZA-934734-B (ZA)
Title: Seals
Inventor: GOLDSWAIN IAN MARTYN
IPC: F16J15/34
Filed: 1993-07-01
Abstract: A mechanical face seal has a first sealing ring (12) mounted non-rotatably and sealed with respect to a shaft (10), a second sealing ring (20) mounted non-rotatably and sealed with respect to a housing (11), said second sealing ring (20) being mounted in axial alignment and being resiliently urged into sealing engagement with the first sealing ring (12). The sealing face (33) of the first sealing ring (12) has a first and second set of grooved areas (40, 41) grooved areas (40, 41) of each set being spaced angularly around the circumference of the sealing face (33) the grooved areas (40) of one set being spaced angularly of the grooved areas (41) of the other set, the grooved areas (40, 41) of both sets opening to one edge of the sealing face (33) and extending part way across the sealing face (33), each grooved area (40, 41) defining a trailing edge relative to the direction of rotation (D) of the first sealing ring, the trailing edge of the grooves (40, 41) being inclined in the plane of the sealing face (33) at an obtuse angle to the direction of rotation (D), the axial depth of the grooved areas (40) of the first set being less than the axial depth of the grooved areas (41) of the second set. <IMAGE>
Patent ZA-951784-B (ZA)
Title: Utilisation des acides sulfoniques comme agents antivicillissement dans une composition cosmetique ou dermatologique
Inventor: BOELLE JEAN PAUL
IPC: A61K8/92
Filed: 1995-03-03
Abstract: Use of cpds. (I) contg. at least one non-neutralised SO3H gp. for the following purposes is new: (1) as agents for combatting intrinsic ageing in and for the mfr. of cosmetic and/or dermatological compsns.; (2) for mfr. of cosmetic and/or dermatological compsns. for combatting wrinkles caused by intrinsic ageing; (3) or mfr. of cosmetic and/or dermatological compsns. for eliminating dead skin cells. (I) include campho-10-sulphonic acid, benzene-1,4-di(3-methylidene-campho-10-sulphonic acid) (Ia),
Patent ZA-961459-B (ZA)
Title: Process for producing a steel sheet or strip for making can, and steel sheet or strip obtained by said process.
Inventor: LESPAGNOL MICHEL
IPC: C22C38/00
Filed: 1996-02-23
Abstract: PCT No. PCT/FR96/00233 Sec. 371 Date Oct. 3, 1997 Sec. 102(e) Date Oct. 3, 1997 PCT Filed Feb. 13, 1996 PCT Pub. No. WO96/26295 PCT Pub. Date Aug. 29, 1996Process for producing a sheet or strip for making a can obtained by drawing and ironing from a steel having the following composition in percentage by weight: Carbon less than 0.008%, Manganese between 0.10 and 0.30%, Nitrogen less than 0.006%, Aluminium between 0.01 and 0.06%, Phosphorus less than 0.015%, Sulphur less than 0.020%, Silicon less than 0.020%, a maximum of 0.08% of one or more elements selected from copper, nickel and chromium, the remainder being iron and residual impurities, in which process the slab is hot rolled into a hot sheet or strip having a thickness less than 3 mm, and then the hot sheet or strip is cold rolled with a reduction of between 83 and 92% and subjected to a recrystallization annealing and cold rerolled with a reduction of between 10 and 40%.
Patent AT-410172-B (AT)
IPC: A61P37/04
Filed: 2000-03-21
Granted: 2003-02-25
Abstract: A method of preparing a vaccine formulation comprising at least one antigen and at least one adjuvant is described, which method is characterized in that at least one antigen is mixed with at least one adjuvant and the mixture subsequently is heat-treated at a temperature of at least 80° C. for a period of time of at least 5 minutes.
Patent GB-2345169-B (GB)
Title: Large block allocation for disk based file systems
Inventor: OLIVER RICHARD JOSEPH
IPC: G06F3/06
Filed: 1998-09-04
Granted: 2002-05-15
Abstract: A system for allocating block sizes in a computer file system is described. Input/output bandwidth requirements for disk access from an application is determined. Also determined is a data transfer characteristic for the drive being accessed. The minimum block size which reduces file fragmentation below a minimum threshold is then calculated as a function of the determined maximum input/output bandwidth and the data characteristic of the drive.
Patent GB-2368184-B (GB)
Title: Magnetrons
Inventor: SALEEM KESAR
IPC: H01J23/40
Filed: 2000-03-30
Granted: 2004-08-18
Abstract: A magnetron includes a decoupling plate located between the end hat of the magnetron cathode and an output coupling member. The use of the decoupling plate presents a high impedance and gives a resonant circuit which is arranged to be resonant at the operating frequency of the magnetron. This prevents or reduces power loss due to capacitive coupling. In another arrangement, the decoupling plate is mounted to a post on the end hat of the magnetron cathode.
Patent GB-2352322-B (GB)
Title: Electrolyte rebalancing system
Inventor: MORRISSEY PATRICK JOHN
IPC: H01M8/04
Filed: 2000-07-03
Granted: 2001-10-10
Abstract: A process for rebalancing the electrolyte system in a regenerative fuel cell using a sulfide/polysulfide reaction in one half of the cell and a bromine/bromide reaction in the other half of the cell comprises passing the electrolyte containing sulfide/polysulfide or bromine/bromide through the +<SP>ve</SP> chamber of an auxiliary cell 51 and passing an electrolyte containing water and being free from polysulfide or bromine through the -<SP>ve</SP> chamber of the auxiliary cell, the auxiliary cell operating so as to oxidise sulfide ions to sulfur or bromide ions to bromine in the +<SP>ve</SP> chamber and to reduce water to hydrogen and hydroxide ions in the -<SP>ve</SP> chamber.
Patent GB-2404692-B (GB)
Title: Friction hinge & window fitting
Inventor: LAPORTA GIOVANNI MARIA
IPC: E05D15/30
Filed: 2000-06-05
Granted: 2005-04-13
Abstract: A friction hinge e.g. for a sash window, comprises a pivoting member (34) coupled to a fixed channel member 32 by an arrangement of stays. A restrictor blocking device (120) is securable in one or more predetermined blocking positions in the channel member to enable users to predetermine variably the extent to which the window can be opened. The blocking device (120) may be removably received in the channel. A locating abutment leg 100 is provided at the proximal end of the pivoting member (34) to assist correct positioning of the window sash relative to the pivoting member during installation.
Patent GB-2452785-B (GB)
Title: Heat exchanger
Inventor: HIROSE HIROKAZU
IPC: F28F9/00
Filed: 2007-01-12
Granted: 2011-12-14
Abstract: A heat exchanger having a core section (4) that is provided with tubes (2), a header tank (5) that communicates with the tubes (2), and an insert (7) that is placed substantially in parallel to the longitudinal direction of the tubes (2) so as to be in contact with the core section (4) at its end, to which heat from the core section (4) is transmitted, and both ends of which are supported by the header tank (5). Stress absorbing sections (74,76,77) for absorbing stress occurring in the longitudinal direction of the insert (7) are formed at the insert (7) such that they are arranged from the upstream side to downstream side of air flow in the insert (7). The end on the upstreammost side of the air flow and the end of the downstreammost side of the air flow at the stress absorbing sections (74,76,77) are arranged so that they are not superposed over each other in the direction of the air flow.
Patent GB-2100374-B (GB)
Title: Column-shift gear-selectors
IPC: G05G5/03
Filed: 1982-06-11
Granted: 1985-07-10
Abstract: A click mechanism in the automatic power transmission gear selector device is mounted onto a bracket for mounting a control rod of the selector device onto a steering column and directly associated with the control rod. By this, click in shifting the automatic power transmission can be directly transmitted to the selector lever through the control rod.
Patent GB-2127094-B (GB)
Title: I c engine intake air cleaner and silencer
Inventor: STAROBINSKY RUDOLF NATANOVICH
IPC: F02M35/14
Filed: 1982-09-10
Granted: 1985-09-04
Abstract: The air cleaner intake duct 2 is provided with two regions 6 and 7 of holes 4 and 5 spaced from the open end of the duct at distances between 0.14 and 0.26 and 0.34 and 0.42 of the total length of the air intake duct 2, respectively. Each of the regions 6 and 7 comprises at least two holes 4 and 5. The total flow area of the holes 4 or 5 is between 0.02 and 0.04 times the mean duct cross-sectional area. The duct (2', Fig. 5) may be curved to follow the cleaner housing 1. <IMAGE>
Patent GB-2175412-B (GB)
Title: Eye testing method and apparatus
Inventor: FISHER JOHN
IPC: A61B3/16
Filed: 1986-05-15
Granted: 1989-06-28
Abstract: A tonometer which comprises a casing adapted to be hand-held, said casing including an optical system (10,26) for forming a viewable image of the cornea of the eye (28), optical detecting means (32,34A,34B) for determining when the tonometer, which is by hand slowly moved around, is axially aligned with the cornea, means (40-58) for firing a controlled puff of air on to the cornea when a condition of stabilised alignment is determined, and circuitry responsive to the outputs of the optical detecting means (32,34A,34B) for determining when a change in image contrast occurs due to applanation of the cornea, said puff firing means and said circuitry being adapted to measure the pressure at the eye (28) when applanation is detected. The tonometer may take the form of a portable system in which at least some of the components are contained in a hand-held unit (100). Alternatively the tonometer may be bench-mounted.
Patent GB-2207087-B (GB)
Title: A method of bonding in particular for a filter cloth assembly
Inventor: LUTZ JR JOHN HESS
IPC: B01D25/12
Filed: 1988-08-05
Granted: 1989-07-05
Abstract: A filter cloth assembly, for use on a filter plate of a centre-feed filter press, comprises first and second sections each including a cloth (14) for disposal on opposite sides of the plate (12), the first section including a tubular stem (28) having a flanged end (30) the latter secured to the first cloth, the second section having a flanged coupling (26) secured to the second cloth and adapted to fit over the stem (28) after the first section has been fitted to one side of the plate with the stem protruding on the opposite side. Methods of bonding otherwise incompatible plastics and elastomers to the stem and coupling are described.
Patent GB-2262937-B (GB)
Title: Imaging of infections using 4-quinolone antibiotics
Inventor: SOLANKI KISHOR KHANDUBHAI
IPC: G21G4/08
Filed: 1992-08-21
Granted: 1995-07-12
Abstract: PCT No. PCT/GB92/01548 Sec. 371 Date May 12, 1993 Sec. 102(e) Date May 12, 1993 PCT Filed Aug. 21, 1992 PCT Pub. No. WO93/03772 PCT Pub. Date Mar. 4, 1993.A 4-quinolone antibiotic compound is used in gamma ray scintigraphy diagnostic imaging of a patient with a metallic radionuclide so as to locate focal infection.
Patent GB-2295388-B (GB)
Title: Preparation of cyclopropane esters
Inventor: BOWDEN MARTIN CHARLES
IPC: C07C69/743
Filed: 1995-10-20
Granted: 1998-02-04
Abstract: PCT No. PCT/GB95/02570 Sec. 371 Date Jan. 31, 1997 Sec. 102(e) Date Jan. 31, 1997 PCT Filed Nov. 2, 1995 PCT Pub. No. WO96/16018 PCT Pub. Date May 30, 1996The invention provides an improved process for the preparation of a lower alkyl ester of 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylic acid in which the corresponding lower alkyl ester of a carboxylic acid selected from 6-bromo-6-chloro-3,3-dimethyl-7,7,7-trifluorohept-2-enoic acid and 6,6-dichloro-3,3-dimethyl-7,7,7-trifluorohept-2-enoic acid is treated with an alkali metal lower alkoxylate in the presence of an aromatic hydrocarbon solvent under conditions under which the lower alcohol of the alkoxylate is removed from the reaction mixture by distillation with the aromatic solvent. The products are useful as intermediates in the manufacture of pyrethroid insecticides.
Patent GB-2335278-B (GB)
Title: Biosensor iontophoretic sampling system and methods of use thereof
Inventor: KIM LYNN
IPC: G01N33/66
Filed: 1999-03-12
Granted: 2000-02-16
Abstract: An automated system for continual transdermal extraction of analytes present in a biological system is provided. The system can be used for detecting and/or measuring the concentration of the analyte using an electrochemical biosensor detection means. The system optionally uses reverse iontophoresis to carry out the continual transdermal extraction of the analytes. <IMAGE>