baber/WOPTO huggingface dataset:
Patent DE-69422374-D1 (DE)
Inventor: MANSOUR TAREK
IPC: C07D/
Filed: 1994-06-07
Granted: 2000-02-03
Abstract: PCT No. PCT/CA94/00311 Sec. 371 Date Feb. 2, 1995 Sec. 102(e) Date Feb. 2, 1995 PCT Filed Jun. 7, 1994 PCT Pub. No. WO94/29301 PCT Pub. Date Dec. 22, 1994The present invention relates to a process for producing predominantly pure cis nucleoside analogues of formula (I), wherein X is S, or O; Y is S, CH2, O or CH(R); wherein R is azido or halogen; and R2 is a purine or pyrimidine base; via the coupling of a silylated purine or pyrimidine base in the presence of an appropriate Lewis acid with a bicyclic intermediate of formula (III) wherein Z is S or O; followed by conversion of the resulting intermediate of formula (II) to an alkyl ester and reduction to yield a compound of formula (I).    <IMAGE>  (I)   <IMAGE>  (II)   <IMAGE>  (III)
Patent DE-69424064-D1 (DE)
Inventor: DE RUBEIS FABIO
IPC: B65D47/10
Filed: 1994-11-01
Granted: 2000-05-25
Abstract: The closure has a locking ring (107) connected to a collar (108), having an internal planar face (109), at a frangible annular portion (110), which can be ruptured to gain immediate access to the contents of a container. A stopper member (120) is fixed to the collar (108) for selectively connecting the closure (100) to an anaesthetic transfer device. A discharge passage (123) and a venting passage (124) extend through the stopper member (120) for communication with a container (103) engaged by the collar (108). A first pierceable diaphragm (125) is located within and occludes the discharge passage (123), and second pierceable diaphragm (129) is located within and occludes the venting passage (124). Upon rupturing the frangible annular portion (110), the internal face (109) prevents the closure (100) from being fitted on another container.
Patent DE-69427650-D1 (DE)
Inventor: JOHANSEN NILS LANGELAND
IPC: C07K7/02
Filed: 1994-12-22
Granted: 2001-08-09
Abstract: PCT No. PCT/DK94/00486 Sec. 371 Date Jun. 6, 1995 Sec. 102(e) Date Jun. 6, 1995 PCT Filed Dec. 22, 1994 PCT Pub. No. WO95/17422 PCT Pub. Date Jun. 29, 1995Novel peptide derivatives, compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone are disclosed. These peptide derivatives have the formula:A-B-C-D-E (-F)pwherein A, B, C, D, E, F and p are as defined in the specification. These peptides exhibit improved resistance to proteolytic degradation as well as improved growth hormone releasing activity.
Patent DE-69429642-D1 (DE)
Inventor: SOHDA TAKASHI
IPC: C07D307/16
Filed: 1994-09-01
Granted: 2002-02-21
Abstract: The present invention provides novel compound of the formulas (Ia) or (I): <CHEM> wherein Q is one or two amino acid residues which may be substituted; R<3> is a carboxyl group which may be esterified or an acyl group; A is an alkylene group; B is hydrogen or an alkyl group which may be substituted or an acyl group; or a salt thereof; <CHEM> wherein R<1> and R<2> may be the same or different and each is hydrogen or a hydrocarbon residue which may be substituted; R<3>, A and B have the same definitions as those shown above; m and n each is 0 or 1; provided that where both m and n are both equal to 0, R<3> is a carboxyl group which may be esterified or an acyl group having not less than 7 carbon atoms; or a salt thereof. The compound (Ia) or (I) shows cathepsin L inhibitory and bone resorption inhibitory activities and are useful as a prophylactic/therapeutic agent for osteoporosis.
Patent DE-69434671-D1 (DE)
Inventor: HILLIER KENNETH
IPC: A62C37/36
Filed: 1994-07-12
Granted: 2006-05-11
Abstract: A fire extinguishing apparatus (10) producing a mist of water vapour with a median droplet diameter of between 50 and 500 micron for extinguishing fires in a confined risk area. The mist being generated through nozzles (18) operating at <2000 kPa (i.e. low pressure). The fire extinguishing apparatus using less than 1.0 litres of water per cubic meter of the risk area in which the fire is contained (i.e. a small volume of water).
Patent DE-69434998-D1 (DE)
Inventor: LEBL MICHAL
IPC: C07K1/04
Filed: 1994-05-27
Granted: 2007-08-23
Abstract: The invention relates to libraries of synthetic test compound attached to separate phase synthesis supports. In particular, the invention relates to libraries of synthetic test compound attached to separate phase synthesis supports that also contain coding molecules that encode the structure of the synthetic test compound. The molecules may be polymers or multiple nonpolymeric molecules. Each of the solid phase synthesis support beads contains a single type of synthetic test compound. The synthetic test compound can have backbone structures with linkages such as amide, urea, carbamate (i.e., urethane), ester, amino, sulfide, disulfide, or carbon-carbon, such as alkane and alkene, or any combination thereof. Examples of subunits suited for the different linkage chemistries are provided. The synthetic test compound can also be molecular scaffolds, such as derivatives of monocyclic of bicyclic carbohydrates, steroids, sugars, heterocyclic structures, polyaromatic structures, or other structures capable of acting as a scaffolding. Examples of suitable molecular scaffolds are provided. The invention also relates to methods of synthesizing such libraries and the use of such libraries to identify and characterize molecules of interest from among the library of synthetic test compound.
Patent DE-69500931-D1 (DE)
Inventor: FREUDENDAHL ERLING
IPC: F16K31/50
Filed: 1995-07-06
Granted: 1997-11-27
Abstract: PCT No. PCT/DK95/00290 Sec. 371 Date Jan. 6, 1997 Sec. 102(e) Date Jan. 6, 1997 PCT Filed Jul. 6, 1995 PCT Pub. No. WO96/01964 PCT Pub. Date Jan. 25, 1996A shut-off valve (1, 101) including a valve housing (2, 102) having a flow passageway (3, 103); a shut-off member (22, 122) displaceably arranged in the housing between an open position and a closed position of the valve flow passageway through an actuator device (15, 115). The actuator device includes a nut member (20, 120) provided with an internal thread (21, 121) having a first thread pitch, and an outer stem member (17, 117) provided with an external thread (19, 119) engaging the internal thread (21, 121) of the nut member, and with an internal thread (18, 118) (21, 121) with a second pitch differing from the first pitch and engaging a corresponding external thread (12, 112) on an inner stem member (6, 106). The threads coacting during the major part of the closing movement of the shut-off member (22, 122) are provided with larger pitch than those coacting during the final part of the closing movement. First coacting stop elements (28, 29; 128, 129) are provided between the two members interengaged by the threads with the largest pitch, the stop elements being adapted to engage each other at the end of the closing movement to ensure a joint turning of the two members in relation to the third member during the final part of the closing movement.
Patent DE-69502427-D1 (DE)
Inventor: DE HOZ GARCIA-BELLIDO ALEJANDR
IPC: H01F27/28
Filed: 1995-03-04
Granted: 1998-06-18
Abstract: Of special application in switched power supply units that have high operating frequencies. The transformer comprises a core and windings formed by planar wire turns. These wire turns are in the form of open rings of a conductive material coated with an insulating material, joined electrically inside the transformer window by a soldering process, having previously eliminated the insulating material they have in two segments of each ring. The end wire turns (E) differ from those in the centre (C) because they have at least one extension (P) that is used as a terminal of the transformer. To make assembly easier, they can have a notch (H) that is shifted progressively by an angle with respect to an origin so that the openings of the wire turns of a winding form a helix. <IMAGE>
Patent DE-69504952-D1 (DE)
Inventor: CANOSA REBOREDO ELENA
IPC: F04C14/22
Filed: 1995-11-06
Granted: 1998-10-29
Abstract: It comprises an integral block of a variator assembly which includes a hydropump cylinder (29), a hydromotor cylinder (39), the end-plates (30, 55) and a intermediary plate (38, 43) with ports for the fluid from the hydropump to the hydromotor at high pressure and from the hydromotor to the hydropump at low pressure to close the circuit. The shafts of the rotors (40, 50) of the hydropump and of the hydromotor have a common geometrical axis (22) which is static with respect to the outside and on which they may rotate independently, said rotation motion being the only motion possible. The variator assembly has as unique possible motion the rotation with respect to a geometrical axis (23) which is fixed with respect to the outside and different from the geometrical axis (65) of the cylinder (29) of the hydropump, different also from the geometrical axis (66) of the cylinder of the hydromotor (39) and different from the common geometrical axes (22) of the rotors. A rotation of the variator assembly is caused from the outside and causes the geometrical axes of the cylinder (29) of the hydropump and of the cylinder (39) of the hydromotor to come closer to or move away from the geometrical axes of their respective rotors (40, 50), thereby causing the variation in the ratio between the rotation speeds of the hydropump rotor (40) and the hydromotor rotor (50). <IMAGE>
Patent DE-69506751-D1 (DE)
Inventor: MENARD MICHAEL J
IPC: A61F13/15
Filed: 1995-03-01
Granted: 1999-02-04
Abstract: Improved method and apparatus for forming absorbent products and the improved absorbent products formed thereby are disclosed. In a first embodiment of the present invention, a rotary die (100) is used to cut ellipsoidal and hyperbolic-shaped portions (52, 54) from a single sheet of material (50) and these shapes are overlaid to form an absorbent structure. The shapes are chosen such that there is no waste of the material and yet the resulting absorbent structure is of a useful shape. Methods are also disclosed whereby two sets of rotary dies are used to simultaneously cut two sheets of material into an arcuate segment and the arcuate segments are overlaid atop each other to form useful absorbent structures. In either embodiment, powders such as superabsorbents may be added to one or more of the surfaces of the components used to construct the absorbent structures. <IMAGE>
Patent DE-69509099-D1 (DE)
Inventor: THOMAS JOHN
IPC: B65D50/04
Filed: 1995-05-03
Granted: 1999-05-20
Abstract: A package suitable for storing and dispensing potentially dangerous material, which is resistant to opening by children yet readily openable by adults. The package is preferably a bottle which has a body and a finish portion. The finish portion has a threaded outer end for mating with a closure. A resiliently deformable cantilevered beam is connected to the finish portion between the threaded outer end and the body of the bottle. The beam is angled outward and downward from the finish portion. The beam has a substantially vertical locking surface and a pushtab spaced along the beam. The angle of the beam is such that the pushtab may be depressed substantially radially toward the finish portion. The locking surface is located between the finish portion and the pushtab so that depression of the pushtab results in a greater beam deflection and lower deflection force at the pushtab than at the locking surface. A bottle closure has threads for rotatably securing the closure to the finish portion of the bottle. The closure also has a tooth projecting radially inward from its lower inner surface and so shaped and positioned that it will engage the locking surface of the resilient beam whenever there is an attempt to unscrew the closure. It thereby prevents removal of the closure until the pushtab is manually depressed to disengage the closure tooth from the locking surface of the cantilevered beam.
Patent DE-69515030-D1 (DE)
Inventor: VOISINE JEAN-CLAUDE
IPC: A47J27/14
Filed: 1995-08-21
Granted: 2000-03-16
Abstract: The grille consists of lower (24) and upper (32) cooking plates and an automatic actuator with a stop for at least one of the plates and a guide to ensure parallel positioning of the two plates. The actuator comprises an electrically-operated power cylinder (40) with an adjustable torque limiter which enables the upper cooking plate to be raised or lowered, while the guide is designed to allow the upper plate to move in an oblique direction and keep its surface parallel to that of the lower plate. The upper plate has a cover (30), and the two cooking plates can be smooth-faced or grooved, and made from soft or semi-hard chrome steel, stainless steel, a soft steel and stainless steel bi-metal or of Teflon (RTM). The plates can be heated by electricity, by gas or induction.
Patent DE-69516843-D1 (DE)
Inventor: HALL JASON HAMILTON
IPC: A42B1/18
Filed: 1995-01-06
Granted: 2000-06-15
Abstract: PCT No. PCT/AU95/00005 Sec. 371 Date May 17, 1996 Sec. 102(e) Date May 17, 1996 PCT Filed Jan. 6, 1995 PCT Pub. No. WO95/18549 PCT Pub. Date Jul. 13, 1995An article of headwear is provided which includes a substantially forwardly projecting peak or visor, an adjustable head engaging band and a length or sheet of material, the head engaging band being attached or attachable to the peak or visor at or near a rear edge thereof, the length or sheet of material being attached or attachable to the peak or visor and extending rearwardly thereof, whereby the peak or visor may be positioned on a wearer's head such that the material covers the wearer's head and hangs therefrom about the shoulders and neck of the wearer, wherein the head engaging band is positioned about a rear of the wearer's head such that the peak or visor is held in position thereon, and the material has a plurality of fasteners to adjust and fasten the material into a plurality of positions to protect a wearer's neck, head, and/or face.
Patent DE-69518006-D1 (DE)
Inventor: AMEY JAMES
IPC: A61K9/48
Filed: 1995-11-09
Granted: 2000-08-17
Abstract: A process for encapsulation of caplets in a capsule comprises the following steps: a. providing empty capsule parts; b. filling at least one of said capsule parts with one or more caplets; c. putting said capsule parts together; and d. treating the combined parts by cold shrinking. The solid dosage forms obtainable by such aprocess are tamper-proof in that they cannot be opened in a way to be reassembled without showing such opening process.
Patent DE-69531701-D1 (DE)
Inventor: WEBB S
IPC: A61K9/127
Filed: 1995-06-19
Granted: 2003-10-09
Abstract: Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of lipophilic drugs such as the vinca alkaloids, and particularly vincristine and vinblastine, to tumors is significantly improved.
Patent DE-69602018-D1 (DE)
Inventor: SHINOHARA KENICHI
IPC: C08K3/04
Filed: 1996-03-13
Granted: 1999-05-12
Abstract: An objective of the invention is to provide a polyacetal resin composition which has excellent resistance to heat aging and grease resistance, has welded sections with no decrease in physical properties, and has improved friction characteristics, and molded articles therefrom. A polyacetal resin composition comprising per 100 parts by weight of a polyacetal resin, 2-7 parts by weight of a polymer composition based on an olefinic polymer having glycidyl-group-containing pendant chains and 0.5-2.5 parts by weight of a dimethyl siloxane polymer of a plasticity of at least one; a polyacetal resin composition further comprising 100 parts by weight of the preceding resin composition along with 0.05-0.5 parts by weight of carbon black; and molded articles therefrom.
Patent DE-69606057-D1 (DE)
Inventor: MCDONALD B
IPC: G06F9/44
Filed: 1996-10-16
Granted: 2000-02-10
Abstract: A system for implementing software objects using an object-prototype model. Objects are defined as collections of properties, each having a unique property name. A collection of property names defines a "shape." The use of shapes frees the representation of an object in memory from the order in which the properties of the object are declared. Methods are defined independently of objects and are applicable to a specified shape, rather than to objects that are derived from a class in which the method is defined. Methods can be applied to any object that has the specified shape or that has a superset of the properties defining the specified shape, regardless of the place of the object in any inheritance hierarchy. The definition of a shape can also include additional selection criteria, such as restrictions on the values of properties, so that the application of a method can be restricted to objects satisfying the specified criteria. The properties of objects can be divided into subgroups representing different aspects of the object and different subgroups of an object can be inherited from different parent objects, based upon either a has-a or an is-a hierarchy. The shape of an object is determine by all of its properties and is not confined by subgroup boundaries.
Patent DE-69606245-D1 (DE)
Inventor: RODA BALZARINI EMILIO
IPC: A47G25/90
Filed: 1996-09-16
Granted: 2000-02-24
Abstract: Device (1) to help an elderly or disabled person to put on hosiery, wherein it comprises:   hollow means (2) of tubular shape and having hole (2a) which allows insertion and admission of the end of the lower limb; hole (2a) has an outer edge (2b) which allows an item of hosiery to be slipped over it and slid axially along the outside of tubular means (2) ;   means (5, 6, 7) capable of varying the dimensions of hole (2a); means (5) capable of rotating tubular means (2) around longitudinal axis (K-K);   support means (8) for holding up device (1).   <IMAGE>
Patent DE-69606854-D1 (DE)
Inventor: STOCKINGER FRIEDRICH
IPC: C08G18/81
Filed: 1996-01-22
Granted: 2000-04-06
Abstract: PCT No. PCT/EP96/00243 Sec. 371 Date Oct. 6, 1997 Sec. 102(e) Date Oct. 6, 1997 PCT Filed Jan. 22, 1996 PCT Pub. No. WO96/24073 PCT Pub. Date Aug. 8, 1996A process for the production of mouldings, in particular contact lenses, in which a water-soluble, crosslinkable polymer is crosslinked in solution, and mouldings, in particular contact lenses, obtainable by this process; and novel water-soluble, crosslinkable polymers which can be employed in the crosslinking process, in particular those based on polyvinyl alcohol having a molecular weight of at least about 2000 which comprises units of the formulae: XI and XII, XI and XIII or XI, XII and XIII. In said Formulae, U is (a) or -Y-NH-CO-O-Z-O-CH=CH2 group, and a unit of the formula XII and a unit of the formula XIII as defined in the description, and crosslinked polymers, either homopolymers or copolymers, made from these novel water-soluble, crosslinkable polymers, a process for the preparation of the novel water-soluble, crosslinkable polymers and the homopolymers and copolymers obtainable therefrom, mouldings made from said homopolymers or copolymers, in particular contact lenses made from these homopolymers or copolymers, and a process for the production of contact lenses using said homopolymers or copolymers.
Patent DE-69623108-D1 (DE)
Inventor: PERONI ENNIO
IPC: H01R4/06
Filed: 1996-11-04
Granted: 2002-09-26
Abstract: A method for producing electrical contacts (30) that can be applied in particular to the web of rails and the like, the method consisting in the steps of:     preparing a stub (1) of copper pipe having gauged dimensions,   inserting the stub (1) in a die (10) of a press, performing a cold deformation to form a flanged head at the end of an internally hollow stem (21), and   extracting the resulting electrical contact (30) from the die.   <IMAGE>
Patent DE-69625899-D1 (DE)
Inventor: WARRIOR PREM
IPC: A01N63/30
Filed: 1996-05-02
Granted: 2003-02-27
Abstract: A method for suppressing plant damage by nematodes which comprises the concurrent administration, to the locus, soil or seeds of plants in need of such treatment, of (a) a metabolite of the fungus Myrothecium verrucaria and (b) a chemical pesticide, as well as synergistic nematocidal compositions useful therein.
Patent DE-69636068-D1 (DE)
Inventor: INGLIS CHARLES
IPC: A61K39/00
Filed: 1996-02-21
Granted: 2006-06-01
Abstract: A genetically disabled mutant virus has a genome which is defective in respect of a selected gene that is essential for the production of infectious new virus particles, and which carries heterologous genetic material encoding an immunomodulatory protein such as GM-CSF, Il-2 or others, such that the mutant virus can infect normal host cells and cause expression of immunomodulatory protein, but the mutant virus cannot cause production of infectious new virus particles except when the virus infects recombinant complementing host cells expressing a gene that provides the function of the essential viral gene; the site of insertion of the heterologous genetic material encoding the immunomodulatory protein preferably being at the site of the defect in the selected viral gene. Uses include prophylactic and therapeutic use in generating an immune response in a subject treated therewith; use in the preparation of an immunogen such as a vaccine for use in tumour therapy; use in the in-vitro expansion of (e.g. virus-specific) cytotoxic T cells; and therapeutic or prophylactic use in corrective gene therapy.
Patent DE-69707695-D1 (DE)
Inventor: FONTANA BRUNO
IPC: B65H49/30
Filed: 1997-07-26
Granted: 2001-11-29
Abstract: PCT No. PCT/EP97/04162 Sec. 371 Date Jan. 27, 1999 Sec. 102(e) Date Jan. 27, 1999 PCT Filed Jul. 26, 1997 PCT Pub. No. WO98/04489 PCT Pub. Date Feb. 5, 1998An apparatus for dispensing electrical or nonelectrical cables, such as television coaxial cables, and a spool to be used together therewith. The apparatus includes a container having a cover for introducing and extracting a spool holding a cable coil and wheels for supporting, centering, and freely rotating the spool inside the container. The spool includes male and female mutually mating flanges. Each of the flanges include an inwardly projecting central part having a frusto conical shape for blocking the innermost turns of the cable coil. At least one of the flanges includes a circular race in which an elastic ring is inserted for assuring cable dragging during rewinding or unwinding of the spool.
Patent DE-69709764-D1 (DE)
Inventor: STIJNS PETRONELLA
IPC: A47B88/493
Filed: 1997-07-18
Granted: 2002-02-21
Abstract: A drawer guide of the over-extendible type, including a movement-control element or elements for controlling the movements of the sections of the drawer guide relative to one another. During operation, the movement-control element or elements remain in connection with multiple sections of the drawer guide. Movements of the control element or elements are dynamically coupled, in such a manner that control is maintained during the complete path of movement of the sections of the drawer guide.
Patent DE-69710289-D1 (DE)
Inventor: HAMPL JR
IPC: D21H27/00
Filed: 1997-10-15
Granted: 2002-03-21
Abstract: The ash characteristics of a paper wrapper for a smoking article are improved by: (a) incorporating CaCO3 (I) of median particle size 0.15-0.5 mu m as filler into the wrapper; and (b) coating the wrapper with a burn control additive (II).
Patent DE-69711571-D1 (DE)
Inventor: LIGHTSEY JOHN W
IPC: C08J3/22
Filed: 1997-12-16
Granted: 2002-05-08
Abstract: A compatibilized silica for incorporation into natural and synthetic polymers in latex form or dry blending operations is described. Said compatibilized silica is formed by the reaction of precipitated or fumed silica with organosilicon coupling compounds in aqueous suspension. Polymer-silica reinforced masterbatches are prepared by addition of the compatibilized silica slurry to natural and synthetic polymer latices. Also described is a process for preparing the compatibilized silica.