baber/WOPTO huggingface dataset:
Patent CO-6230982-A2 (CO)
Title: Compuestos triciclicos que contienen actividad antagonista de factor de liberacion de corticotropina y composiciones farmaceuticas que los contienen
Inventor: ASO KAZUYOSHI
IPC: C07D487/04
Filed: 2010-08-20
Abstract: Se proporciona un compuesto de la fórmula (I'): en donde X es un nitrógeno o CRx, Rx es un hidrógeno, etc., R1 es un grupo de hidrocarburo opcionalmente substituido etc., R2 es un grupo de hidrocarburo opcionalmente substituido, etc., el anillo A es un anillo heterocíclico de 5- a -8-miembros etc., y cada uno de Y1, Y2 e Y3 es un carbono opcionalmente substituido o un nitrógeno, etc.; o una sal del mismo o un profármaco del mismo, que tiene actividad antagonista del receptor CRF y proporciona también el uso del mismo. 1.- Un compuesto representado por la fórmula (I'):en donde X es un nitrógeno o CRx (en donde Rx es un hidrógeno o un C1-9 alquilo, siempre y cuando X forme un enlace doble, Rx está ausente); R1 es (1) un grupo de hidrocarburo opcionalmente substituido, (2) un acilo, (3) un grupo heterocíclico opcionalmente substituido, (4) un amino opcionalmente substituido, (5) nitro, (6) un hidroxi opcionalmente substituido, (7) un mercapto opcionalmente substituido, (8) ciano, o (9) halógeno; R2 es (1) un grupo de hidrocarburo opcionalmente substituido, (2) un acilo, (3) un grupo heterocíclico opcionalmente substituido, o (4) un amino opcionalmente substituido, siempre y cuando se excluyan metilo, etilo, propilo y metoximetilo; el anillo A es un anillo heterocíclico de 5- a 8- miembros opcionalmente substituido; y Y1, Y2 e Y3 cada uno son un carbono o un nitrógeno opcionalmente substituido; excluyendo (i) un compuesto en donde Y1 e Y3 cada uno son un nitrógeno, R1 es amino y R2 es alquilo opcionalmente substituido, (ii) 2,4,7-tricloro-9-(4-metilfenil)-6,7,8,9-tetrahidropirimido [2,1-f] purina, (iii) N-acetil-N-(8-acetil-7,8-dihidro-6H-imidazo[2,1-f]purin-4-il)acetamida, y (iv) un compuesto en donde R1 y R2 cada uno son simultáneamente o una sal del mismo.
Patent CO-6721022-A2 (CO)
Title: Bomba centrífuga de alta presión de múltiples etapas para fracturar reservas de hidrocarburos
Inventor: PETTIGREW DANA
IPC: F04D1/06
Filed: 2013-06-19
Abstract: La presente invención se relaciona con un diseño de bomba centrífuga de múltiples etapas, que tiene difusores, propulsores, y un eje, insertados dentro de una carcasa para alta presión, de tal manera que esta ensamble se cierra completamente dentro de la carcasa, y esta tiene suficiente resistencia para ser adecuada para la contención segura de presión de los fluidos que se bombean. Esta invención describe los detalles técnicos utilizados para reconfigurar el diseño de bomba centrífuga de múltiples etapas con el fin de aumentar las capacidades de presión de descarga de más6,000 psig de los diseños actuales.
Patent CO-6751274-A2 (CO)
Title: Tratamiento de la osteoartritis y del dolor
Inventor: KAMATH RAJESH V
IPC: A61K39/395
Filed: 2013-08-27
Abstract: Tratamiento de la osteoartritis y del dolor usando proteínas de unión a IL-1a e IL-1ß, incluyendo anticuerpos anti-IL-1a y anti-IL-1ß y proteínas de unión IL-1a e IL-1ß manipuladas multivalentes y de especificidad múltiple.
Patent DD-160206-A2 (DD)
Title: Stator fuer elektromaschinen und verfahren zu seiner herstellung
Inventor: GLEICHMANN WALTER
IPC: H02K15/08
Filed: 1980-06-16
Abstract: Die Erfindung betrifft einen Stator fuer Elektromaschinen und das Verfahren zu seiner Herstellung, der insbesondere bei Elektromotoren fuer Handruehr- und Mixgeraete, Mehrzweckschneider, Kaffeemuehlen oder dergleichen Anwendung finden soll. Die Erfindung verfolgt das Ziel, einen Stator fuer Elektromaschinen und ein Verfahren zu seiner Herstellung nach der vorteilhaften Hauptanmeldung WP 154150 zu schaffen, der eine minimale Baugroesse aufweist, wenig materialaufwendig ist und eine neue Qualitaet der Technologie ermoeglicht. Der Stator fuer Elektromaschinen ist erfindungsgemaess dadurch gekennzeichnet, dass ein Blechzuschnitt eines Stators ein Querjoch sowie ein rechtes und linkes Seitenjoch aufweist und dass auf dem rechten Seitenjoch ein Spulenkoerper mit Wicklung und auf dem linken Seitenjoch ein Spulenkoerper mit Wicklung und auf dem Querjoch ein breiter Spulenkoerper mit einer Wicklung angebracht ist. Die Erfindung kann darueber hinaus bei Staubsaugermotoren, Spielzeugmotoren, Motoren fuer Bohrmaschinen u. dgl. angewendet werden.
Patent EP-1028240-A2 (EP)
Inventor: ISHII HITOSHI
IPC: F02P5/15
Filed: 2000-02-08
Abstract: An idling control system for a two-plug type
internal combustion engine is comprised of an idling
detector, an engine rotation speed detector and a
controller coupled to the detectors. The controller
decides whether the engine rotation speed in idling
is smaller than an idling speed by a predetermined
value. When this decision is affirmative, the
controller differentiates ignition timings of the
two spark plugs of each cylinder. This arrangement
enables the engine with this system to perform
preferable idling performances of generating a
torque in response to the input of the external
torque and of continuing the combustion against the
drop of the engine rotation speed.
Patent EP-1059214-A2 (EP)
Inventor: WEIGELE GEBHARD
IPC: B60S3/00
Filed: 2000-03-16
Abstract: The transportation unit has at least two direction changing arrangements (UR,AR) for changing the direction of movement of a transport belt (G) on which are mounted a number of cams (N) at intervals so that at least one cam is arranged behind a wheel (RE) of a vehicle to be transported.
Patent EP-1046691-A2 (EP)
Inventor: BLUMENTHAL MITCHELL J
IPC: C09J167/02
Filed: 2000-04-10
Abstract: A hot melt adhesive composition comprising (a) greater than 40% by weight of a
polymeric component; and (b) 5 to 40% by weight of a high hydroxyl number compound, with
hydroxyl number greater than 100 mg KOH/g.
Patent EP-1043904-A2 (EP)
Inventor: ITOH TAIZOH
IPC: H04M1/72
Filed: 2000-04-06
Abstract: There is provided a communication apparatus (21),
comprising a plurality of radio transmitter sections (4a, 6a),
which is capable of suppressing unnecessary radiowaves from
being generated due to mutual modulation distortion without
increasing the size and weight of the whole apparatus. When
the communication apparatus (21) receives a UI (RT = paging,
MM = -, CC = -) signal from a radio base station and it coincides
with the ID of own station during when transmitting means (6a)
of a PHS RF section (6) is operative, it rejects a process for
the request of "Call Incoming in PDC" accompanying to that and
makes no transmission by the PDC transmitting means (4a).
Therefore, no transmission is made simultaneously by the PDC
transmitting means (4a) and the PHS transmitting means (6a) and
the quality of the radiowaves transmitted from the PHS
transmitting means (6a) may be kept high.
Patent EP-1050315-A2 (EP)
Inventor: UGO FERRANDO
IPC: A61M25/00
Filed: 2000-05-04
Abstract: Drainage tube (1) presenting a main duct (4), a
distal drainage portion (5) arranged at a free end of
the duct (4) itself and an intrinsic blocking device
for blocking the tube (1) itself; the intrinsic
blocking device is defined by an inflatable balloon
(13) which is arranged along the duct (4) above the
distal portion (5) and is suitable for being inflated
near an entry opening (2) of the drainage tube (1)
into the body of the patient; and a fixing flap (14)
integral to the duct (4) and arranged on opposite
sides of the distal portion (5) with regard to the
balloon (13) which is used to further fix the tube
(1) with regard to the entry opening(2).
Patent EP-1070869-A2 (EP)
Inventor: EGUCHI TAKAHIRO
IPC: B60W10/10
Filed: 2000-07-06
Abstract: In an apparatus for controlling a starting clutch
(7) of a vehicle having a function of stopping engine
idling so that an engine (1) is automatically stopped
under given conditions when the vehicle is at a
standstill, the starting clutch (7) being disposed in a
transmission of the vehicle in series with a belt type
continuously variable transmission mechanism (5) which
receives an input of a power from the engine through a
power transmission mechanism having built therein
hydraulically operated frictional engaging elements (64,
65), the vehicle start-up from the state of engine
stopping is made smoothly at a good response. At the time
of vehicle start-up from the state of engine stopping,
when the rotational speed (NDR) of the drive pulley (50)
of the transmission mechanism (6) has increased to a
predetermined speed (YNDR2), the control mode of the
starting clutch is switched from the waiting mode in which
the engaging force of the starting clutch (7) is kept
below a creeping force which causes the vehicle to creep,
to a running mode in which the engaging force of the
starting clutch (7) is increased above the creeping force.
Patent EP-1074750-A2 (EP)
Inventor: FAVOTTO SERGIO
IPC: F15B15/22
Filed: 2000-08-02
Abstract: The pressure fluid actuator (10) comprises a tubular
body (11) and closing heads (12,13) to define a
piston chamber (14) in which a piston (15) may
reciprocate. The piston (15), at both ends, is
provided with a damping bush (25) which may protrude
into a flow damping chamber (18,19) in each closing
head (12,13) connected to a fluid inlet/outlet port
(16,17); a conduit (25A) comprising a flow throttling
valve (23) is branched between each side of the
piston chamber (14) and the damping chamber (18,19)
in each closing head (12,13). The flow damping bush
(25) comprises a longitudinally extending fluid
supply duct (32) provided with a pressure actuated
unidirectional flow control valve (30,32) which
prevent the pressure fluid to flow from the piston
chamber (14) into the damping chamber (18,19) during
damping at the end of a piston stroke, while allowing
flow circulation into the piston chamber (14) when
the bush (25) is within the damping chamber (18,19)
at the beginning of a piston stroke.
Patent EP-1090883-A2 (EP)
Inventor: SOPPE ALFRED
IPC: C01D3/04
Filed: 2000-09-26
Abstract: Strengthening sols in a sodium chloride (NaCl) electrolysis apparatus comprises storing the required NaCl salt in a mass flow silo with a liquid supernatant and continuously adding to the solutizer.
Patent EP-1091592-A2 (EP)
Inventor: OHGOSE HIDEYUKI
IPC: H04N19/60
Filed: 2000-10-06
Abstract: A video signal encoding apparatus for enlarging a video
signal by subjecting it to a coding process. The apparatus, using
m×n blocks (m, n: natural number) as the unit block for coding a
motion picture, performs DCT calculation and quantization, and,
then, converting the block into s×t blocks (s, t: natural number),
performs variable length coding. Thus, the apparatus generates
compressed data of an enlarged motion picture and delivers the
enlarged output. In the local decoder of the apparatus, it is
switch selected by a switcher whether m×n inverse quantization
coefficients, obtained by inverse quantization, are to be decoded by
an s x t IDCT unit or by an m x n IDCT unit, in accordance with the
accuracy in motion compensation. Further, the apparatus has a
resizing unit for adjusting a motion-compensated reference picture
to the picture size of an input image. The video signal encoding
apparatus performs the encoding by enlarging a motion picture in a
frequency domain so that the amount of data calculation in the
encoding is decreased and deterioration in picture quality is
suppressed.
Patent EP-1081198-A2 (EP)
Inventor: ERDTMANN DAVID
IPC: C09D11/00
Filed: 2000-08-21
Abstract: A color ink jet ink set for color printing comprising:
   (a) a yellow ink comprising a carrier and Direct Yellow 107,
Direct Yellow 132 or Direct Yellow 86;   (b) a magenta ink comprising a carrier and a water soluble,
transition metal complex of an 8-heterocyclylazo-5-hydroxyquinoline dye;
and   (c) a cyan ink comprising a carrier and a sulfonated copper
phthalocyanine dye.
Patent EP-1107260-A2 (EP)
Title: Gitter zur Absorption von Röntgenstrahlen
Inventor: SUCH OLAF DR
IPC: G01T7/00
Filed: 2000-11-22
Abstract: Die Erfindung betrifft ein Gitter (3) zur Absorption von Röntgenstrahlen (11) bei dem zur einfachen Herstellung bei entsprechender Robustheit auch für großflächige Röntgendetektoren ein Streustrahlengitter zur Reduzierung der Streustrahlung durch Anordnen mehrerer Schichten, die beabstandete Drahtelemente (10) enthalten, gebildet wird. <IMAGE>
Patent EP-1106416-A2 (EP)
Inventor: MENDIS KOLITA
IPC: B60K23/02
Filed: 2000-12-05
Abstract: A control pedal unit for a vehicle comprising a support structure (1), a pedal connected to said
support structure and means responsive to the movement of the pedal for generating a signal
corresponding to the position and/or change of position of the pedal, wherein that the pedal is
formed as a resilient body.
Patent EP-1085471-A2 (EP)
Inventor: KANETAKA KATSUYUKI
IPC: A63F13/52
Filed: 2000-09-14
Abstract: A three-dimensional CG image is created with a small processing
volume. As shown in Figs. 5A through 5G, positions in a three-dimensional
space associated with sparks of a firework are calculated in accordance with
motion characteristics of the sparks (Figs. 5A, 5B and 5C). Positions on a
camera screen are obtained which are positions where calculated positions of
the sparks at the current point in time in Fig. 5C are projected, and a spark
texture D is drawn in those positions to represent a firework as shown in Fig.
5F.
Patent EP-1116904-A2 (EP)
Inventor: SUGIMOTO KIYOSHI
IPC: F16J15/08
Filed: 2000-12-15
Abstract: A metal gasket (1) is described which has a structure with no beads so
that the need for dies used for molding is eliminated, thereby facilitating
the processing of the gasket and achieving good cost performance, and
which is excellent in sealing ability. The metal gasket (1) comprises (i) an
elastic metal plate (2,3) having a base (13) and folded-back portions (15) each of which is
formed so as to create a clearance together with the base and disposed so as
to extend around a bore hole (7) and (ii) a metal plate (4) which is thicker than the
elastic metal plate (2,3) and has lower level portions (21,22) each of which is located at a
position closed to each bore hole (7), and the elastic metal plate (2,3) and the metal
plate (4) are laminated such that each folded-back portion (15) of the elastic metal
plate (2,3) faces the lower level portion (21,22) of the metal plate (4).
Patent EP-1111473-A2 (EP)
Inventor: BURGHOORN JACOBUS
IPC: G03F9/00
Filed: 2000-12-21
Abstract: In a lithographic apparatus having a movable object table in vacuum, an
interferometer-based alignment system for detecting the position of that object table has a
passive part in vacuum and an active part outside the vacuum chamber. The active part
contains the beam generator, e.g. a laser, and the electronic detectors whilst the passive part
contains the illumination and imaging optics. The two parts are coupled by optical fibers. The
interferometer may make use of different diffraction orders from measurement and reference
gratings and the order separation may be included in the passive part.
Patent EP-1233856-A2 (EP)
Inventor: CUTLER PHILIP WILLIAM
IPC: B29C67/20
Filed: 2000-04-27
Abstract: A mold assembly (10) and method for molding a substantially hemispherical construct from pre-expanded polystyrene beads. The mold assembly includes a female half mold (14) and a mating male half mold (16), a first male mold insert (18) mountable on the male half mold and a second male mold insert (20) mountable on the first male mold insert. The beads are initially molded under heat and compression between the female half mold and the first insert to form first intermediate product of a first volume. The intermediate product is thereafter molded under heat and compression between the female half mold and the second insert to a second reduced volume to form a compressed, second intermediate product. The second intermediate product is remolded to the same volume and then backfilled between the male half mold and female half mold with additional pre-expanded polystyrene beads to form an energy absorbing inner layer.
Patent EP-1145383-A2 (EP)
Title: Electrical conductivity connectors
Inventor: HORNE DAVID
IPC: H01R11/12
Filed: 2000-08-11
Abstract: An electrical conductivity connector comprises a conductive plate (11) for connection to a metal enclosure (1) of multi-panel (3, 4) form, a plurality of leads (13), each lead being permanently secured at one end (13a) thereof to the conductive member, the opposite end (13b) of each lead carrying a captive nut assembly (20) for electrically connecting the conductive member (11) to a respective panel (3, 4) or frame member of the enclosure. Each captive nut assembly (20) comprises a nut (23) provided with an integral axial extension (29) of reduced lateral dimensions compared with the diameter of the nut, the axial extension extending through a hole (28) in a connector tag (24') and being captively connected at the free end thereof to a washer (25) positioned on the opposite side of the tag from the nut.
Patent EP-1204412-A2 (EP)
Inventor: CARSON DENNIS A
IPC: A61P35/02
Filed: 2000-07-13
Abstract: A method of treating multiple myeloma (MM) is provided comprising administering an amount of etodolac to a subject afflicted with MM that is effective to selectively reduce the viability of and/or sensitize the cancer cells to an anti-cancer agent.
Patent EP-1251812-A2 (EP)
Inventor: PAULEY SUZANNE M
IPC: A61F13/20
Filed: 2000-10-06
Abstract: There is provided a tampon pledget (5) that expands without the aid of moisture or menses. The tampon pledget has a plurality of high resiliency, non-absorbent materials and a plurality of absorbent materials. The tampon pledget has improved comfort as compared to conventional fully compressed tampon pledgets. The tampon pledget preferably has all of its non-absorbent and absorbent materials enclosed in a coverstock (12). The coverstock (12) may be inverted or turned inside out, prior to filling the coverstock with a plurality of non-absorbent and absorbent materials.
Patent EP-1224098-A2 (EP)
Inventor: MEDIMUREC SLAVKO
IPC: B60R1/00
Filed: 2000-10-18
Abstract: The invention refers to the articulated arm of the rear mirror for cars, bicycles and/or to that of an additional internal car rear mirror, suitable for efficient mounting either on the handlebar or inside the car and allowing for simple adjustment of the viewing position. The articulated rear mirror arm referred to in this invention allows for simple adjustment and arresting of the selected position by means of the articulated parts including the rod shaped structure of the carrier element (1, 14), the intermediate connection element (2, 15) and the fixing element (3, 16). The mirror (4) is with its frame (5) fixed to one end of the intermediate connection element, thereby forming an articulation.
Patent EP-1230381-A2 (EP)
Inventor: KAWASAKI GLENN
IPC: C12Q1/32
Filed: 2000-11-02
Abstract: The present invention provides an enzymatic cycling assay for assessing the amount of homocysteine and/or cystathionine in a solution such as blood derivatives, or urine. The assay comprises the steps of contacting the solution containing homocysteine and/or cystathionine to form a reaction mixture, with CBS, or a derivative thereof, L-serine, and CBL, or a derivative thereof, for a time period sufficient to catalyze the cyclical conversion of homocysteine form to cystathionine and the reconversion of cystathionine to homocysteine with the production of pyruvate and ammonia; determining the amount of homocysteine and/or ammonia present in the reaction mixture; and determining the amount of homocysteine and/or cystathionine present in the solution based on the amount of pyruvate and/or ammonia formed. Expression vectors and isolation procedures for CBS, or derivatives thereof, and CBL, or derivatives thereof, are also provided as well as test kits for carrying out the assay. In preferred embodiments, the assays can be conducted in 15 minutes or less, with a minimum of enzyme usage. Figure (1) depicts absorbance versus time plots obtained using aqueous solutions of pyruvate (5-100uM) demonstrating the quantiation of pyruvate where Table 1 describes reagent components used and Table2 describes instrument settings.
Patent EP-1246574-A2 (EP)
Inventor: GALDONIK JASON A
IPC: A61B17/115
Filed: 2000-11-29
Abstract: L'invention porte sur un appareil et sur des procédés de fabrication d'un raccordement automatique entre un premier conduit et un second conduit. Une structure de raccord pourvue d'une première partie terminale et d'une seconde partie terminale est positionnée autour d'un cathéter à ballonnet qui, lorsqu'il est sous pression, se dilate jusqu'à un certain point au niveau de son extrémité distale. Le ballonnet agrandit la structure du raccord lorsqu'elle est positionnée au niveau de son extrémité distale afin de créer l'anastomose et réduit en même temps la longueur axiale du raccord, ce qui comprime le premier conduit contre le second, créant ainsi un joint hémodynamique et un raccordement solide entre les des deux conduits. Après agrandissement, la structure du raccord reste en place et ajoute une structure à l'anastomose. Au cours de l'introduction de l'appareil, la seconde extrémité du raccord est recouverte d'un ensemble cône avant afin d'éviter un trauma sur le second conduit. L'ensemble cône avant a une structure flexible qui peut changer de configuration pour exposer le second ensemble d'éléments après leur insertion dans le second conduit afin de faciliter le retrait du cône avant après déploiement.
Patent EP-1228305-A2 (EP)
Inventor: MIEDL BERNHARD
IPC: F02M61/00
Filed: 2000-11-03
Abstract: L'invention concerne une douille amortissante conçue en particulier pour des soupapes d'injection de moteurs à allumage commandé, permettant de compenser de manière efficace et fiable des tolérances de fabrication et de réglage. Cette compensation est effectuée dans un première direction au moyen de processus de déroulement sur deux calottes (14) diamétralement opposées, et dans une direction perpendiculaire à la première au moyen de diverses déviations d'arcs souples diamétralement opposés (15).
Patent EP-1239858-A2 (EP)
Inventor: DAVIDSON ELIZABETH JANINA
IPC: A61K31/4458
Filed: 2000-12-15
Abstract: Single enantiomer-threo-methylphenidate is useful in the therapy of a convulsant state, e.g. epilepsy, a bipolar disorder or narcolepsy. It may be administered topically.
Patent EP-1236112-A2 (EP)
Inventor: GILL RICHARD A
IPC: G11B20/18
Filed: 2000-11-30
Abstract: L'invention concerne un système d'enregistrement de l'historique lié aux données d'écriture sur un support de réécriture comprenant une tête d'accès destinée à écrire des données sur le support et à les lire. Un moteur de commande déplace le support au-delà de la tête d'accès et un dispositif de formatage d'écriture formate les données en un bloc à écrire sur le support. Ce dispositif de formatage de lecture détecte les erreurs concernant les données lues sur le support. Une unité de commande détermine s'il y a lieu de procéder à la correction des erreurs selon que l'erreur est détectée à la lecture et permet au dispositif de formatage l'insertion d'indications pour la procédure de correction des erreurs dans le bloc, après quoi l'opération de correction d'erreurs est effectuée. Ce processus est répété jusqu'à ce qu'une écriture correcte soit effectuée ou que le support soit considéré comme défectueux.