baber/WOPTO huggingface dataset:
Patent CA-3011049-A1 (CA)
Title: Compositions pour lier des domaines de liaison a l'adn et des domaines de clivage
Inventor: MILLER JEFFREY C
IPC: C07K19/00
Filed: 2016-12-15
Abstract: L'invention concerne des compositions pour lier des domaines de liaison à l'ADN et des domaines de clivage (ou des demi-domaines de clivage) pour former des nucléases d'origine non naturelle avec de nouvelles configurations. L'invention concerne également des procédés de production et d'utilisation de compositions comprenant ces lieurs.
Patent CA-3011211-A1 (CA)
Inventor: BELENKIY ARKADIY
IPC: A46B11/00
Filed: 2017-01-11
Abstract: An oral care device comprising: a hollow shaft having a suction and a cleaning portion wherein the suction and the cleaning portion are fluidically connected; a suction activator provided to the shaft; a material supply channel comprising at least one material supply opening, wherein the material supply opening is configured to reversibly receive a pod; and at least one opening at the cleaning portion fluidically connected to a suction. In addition, there is provided a pod configured to be attached to an oral care device as disclosed above, the pod comprising a body configured to contain a material for treating an oral cavity, a neck, and a seal separating the body from the neck. A kit comprising the oral care device and a plurality of pods, a method for using the same, and additional embodiments of the present subject matter, are disclosed herein.
Patent CA-3012806-A1 (CA)
Title: Tricyclic compounds having antimitotic and/or antitumor activity and methods of use thereof
Inventor: GANGJEE ALEEM
IPC: C07D495/04
Filed: 2009-07-08
Abstract: The present invention provides tricyclic compounds, pharmaceutically acceptable    salts,    prodrugs,    solvates,    or            hydrates thereof, having antimitotic activity, anti-multidrug resistance activity, for example       P-glycoprotein    inhibition,    and              antitumor activity, and which inhibit paclitaxal sensitive and resistant tumor cells.  Also provided are methods of utilizing these compounds for treating tumor cells and inhibiting mitosis of cancerous cells.
Patent CA-3013855-A1 (CA)
Title: An extended blockchain design having a state chain
Inventor: DENG ENYAN
Filed: 2018-08-10
Abstract: The present invention describes an extensible blockchain design that incorporates a state chain. The state chain stores all the account status information in the blockchain system. The state chain maintains the account status information. The state chain can perform branch numbering, chain splitting, chain merging and parallel block building on the blockchain system. Adding the state chain to maintain the account state information makes the operations on the transaction blockchain more secure and efficient.
Patent CA-3014345-A1 (CA)
Title: Pet containers with enhanced thermal properties and process for making same
Inventor: SILVERS KERRY W
IPC: B29C49/12
Filed: 2011-12-15
Abstract: The process comprises steps of, on an integrated system injecting a molten PET    resin into an injection mold cavity to form a preform (22); removing the preform (22) while the preform (22) is at a temperature of from 75° C. to 130° C.;  conveying the preform to a conditioning station at a rate such that the temperature of the surface of the preform (22) does not decrease more than 5° C.;  conditioning the preform by selectively heating specific areas of the preform (22) comprising at least the neck forming (51, 52), barrel forming (53), heel forming (54), and base forming (55) zones of the preform (22) to achieve a temperature gradient in the specific areas of 20° C; conveying the conditioned preform (22) to a blow mold station at a rate such that the temperature of the surface of the preform does not decrease more than 5° C.
Patent CA-3014915-A1 (CA)
Inventor: BEYMORE PAUL MICHAEL
IPC: G01J3/50
Filed: 2017-02-17
Abstract: A computerized method for displaying matches of a paint sample to various proposed paint coatings includes receiving one or more coating texture variables of a target coating from a coating-measurement instrument. The method also includes displaying, on a digital display device, effect texture ratings for multiple respective proposed coating matches on a digital display device, wherein the effect texture ratings indicate a similarity between the one or more coating texture variables of the target coating and respective coating textures variables of each of the respective proposed coating matches. In addition, the method includes ordering the proposed coating matches, wherein the ordering indicates a strength in similarity between the target coating and each of the proposed coating matches with respect to the effect texture ratings.
Patent CA-3016243-A1 (CA)
Title: Pores comprenant des monomeres csgg mutants
Inventor: JAYASINGHE LAKMAL
IPC: C07K16/12
Filed: 2017-03-02
Abstract: L'invention concerne des formes mutantes de CsgG. L'invention concerne également la détection et la caractérisation d'analytes à l'aide de CsgG.
Patent CA-3016272-A1 (CA)
Inventor: KRAUS ANDREAS
IPC: A61K47/36
Filed: 2017-03-21
Abstract: The present invention generally relates to a modified hyaluronic acid (HA) and to a method for making same, more specifically to a (poly)glycerol-modified HA derivative prepared by grafting glycidol to HA. The present invention also relates to the use of the HA derivative for preparing a dermal filler composition, a hydrogel comprising cross-linked HA and the (poly)glycerol-modified HA derivative, and a method for preparing said hydrogel. Furthermore, the present invention relates to the use of the hydrogel as a cosmetic and/or aesthetic product, in particular as a dermal filler for tissue filling, replacing and/or augmenting.
Patent CA-3018623-A1 (CA)
Inventor: GUO JAMES
IPC: G01N1/44
Filed: 2017-03-21
Abstract: A device and method of processing sample slides. The device comprises a container (301), a base (302), a heating device (303), a slide cover (100), a slide (101), a slide support (200), a liquid outlet (307), a liquid inlet (308), a controller (309), a thermocouple (312), a temperature display screen (313), a constant temperature control time display window (314), and a constant temperature control time adjustment button (315). The embodiment can perform processing such as reagent adding, cleaning, heat treatment, constant temperature control, and dehydration, on a large quantity of sample slides in the same device, and carry out the entire process of sample slide processing without needing manually picking up or transferring the slides, reducing human intervention or interruption, saving time, simplifying operations, and reducing operation errors.
Patent CA-3018817-A1 (CA)
Inventor: EUDES FRANCOIS
IPC: A61K48/00
Filed: 2017-03-23
Abstract: Compositions including a nanocomplex of a polynucleotide with a cell-penetrating peptide and a quaternary phosphonium salt, such as tetrabutylphosphonium bromide (TBPB), are useful for delivering polynucleotides such as DNA or RNA into cells.
Patent CA-3019471-A1 (CA)
Title: Ranging and resistivity evaluation using current signals
Inventor: WU HSU-HSIANG
IPC: G01V3/08
Filed: 2016-05-06
Abstract: Methods, systems, and computer program products use current leakage rates to evaluate the resistivity of a subterranean formation around a drilling well in conjunction with a ranging operation. The evaluation entails obtaining a current distribution along a section of the drilling well as part of a ranging measurement. The current distribution allows the current leakage rate to be determined along that section of the drilling well. Multiple current leakage rates may then be determined along the drilling well to produce a leakage rate curve that may be matched with modeled or known leakage rate curves to estimate the formation resistivity around the drilling well. Formation resistivity may also be calculated from the current distribution using an appropriate equation. The ability to obtain a current distribution along a section of the drilling well as part of a ranging measurement allows formation resistivity to be evaluated in conjunction with ranging operations.
Patent CA-3019840-A1 (CA)
Inventor: LAMPROPOULOS FRED
IPC: A61M31/00
Filed: 2017-04-04
Abstract: Medical devices for delivering compositions or medical articles to a patient are disclosed. The medical plug delivery devices can include a fluid delivery device (e.g., a syringe), a frame, and a rotatable magazine. The rotatable magazine can include a plurality of chambers that each hold a composition or a medical article (e.g., a medical plug). By rotating the rotatable magazine relative to the frame, material within the chambers of the rotatable magazine can be sequentially deployed to a patient.
Patent CA-3021407-A1 (CA)
Inventor: KNOWLES SIMON CHRISTIAN
IPC: G06F9/38
Filed: 2018-10-19
Abstract: A processor comprising: an execution unit, multiple context register sets, a scheduler arranged to control the execution unit to provide a repeating sequence of temporally interleaved time slots, thereby enabling at least one respective worker thread to be allocated for execution in each respective one of some or all of the time slots, wherein a program state of the respective worker thread currently executing in each time slot is maintained in a respective one of the context register sets; and an exit state register arranged to store an aggregated exit state the worker threads. The instruction set comprises an exit instruction for inclusion in each worker thread, the exit state instruction taking an individual exit state of the respective thread as an operand. The exit instruction terminates the respective worker and also cause the individual exit state specified in the operand to contribute to the aggregated exit state.
Patent CA-3024109-A1 (CA)
Title: Stock level indication apparatus and method
Inventor: JONES NICHOLAUS A
IPC: G06Q10/00
Filed: 2017-05-15
Abstract: In some embodiments, systems, apparatuses, and methods are provided herein useful to provide an indication of a stock level of a product support member. Compressed air is directed through a plurality of bores extending through the product support member. A sensor reading of the compressed air can be utilized to determine whether there are products stocked on the product support member due to the products blocking one or more of the bores.
Patent CA-3026188-A1 (CA)
Inventor: SMETS PATRIK
IPC: G06Q20/32
Filed: 2017-07-27
Abstract: La présente invention concerne un procédé permettant de réaliser une interaction améliorée entre un premier dispositif informatique et un second dispositif informatique. Un premier canal permettant une connexion entre le premier dispositif informatique et le second dispositif informatique à l'aide d'une technologie de communication à courte portée et un second canal permettant une communication entre le premier dispositif informatique et le second dispositif informatique à l'aide d'une technologie de communication sont établis. Une première interaction est réalisée à l'aide du premier canal et une interaction supplémentaire est réalisée à l'aide du second canal. La présente invention concerne également des premier et second dispositifs informatiques appropriés.
Patent CA-3026846-A1 (CA)
Inventor: WISINGER JOHN LESLIE
IPC: E21B23/00
Filed: 2016-07-15
Abstract: A carrier system may be used to position a wireline tool within a wellbore. The system includes a wireline tool carrier disposed on the end of a coiled tubing string. The wireline carrier tool includes a tubular member and stabilizers which secure the wireline tool within an internal passageway of the tubular member. The internal passageway defines a fluid flow path which facilitates fluid communication between the coiled tubing string and any device or wellbore portion below the wireline tool carrier. As the system is advanced within the wellbore fluid is conveyed around the wireline tool through the fluid flow path to remove obstructions that would otherwise inhibit the placement of the wireline tool within a deviated wellbore. Fluid conveyed through the system and around the wireline tool may also be used to perform various well stimulation and intervention functions.
Patent CA-3027489-A1 (CA)
Inventor: HARRELL CARL RANDALL
IPC: A61K9/00
Filed: 2017-06-13
Abstract: Formulations of human amniotic fluid and methods of use thereof for treatment of lung disorders and/or injuries have been developed. The formulations are suitable for topical delivery to the lung for treatment of lung disorders including chronic obstructive pulmonary disorders (COPD), asthma, emphysema, bronchiectasis, chronic bronchitis, interstitial lung disease, alpha-1 antitrypsin emphysema, as well as for treatment of acute lung injuries. Methods including administering specifically formulated, diluted sterile decellularized human amniotic fluids topically to the lungs, preferably as aerosol droplets, are described. In particular, the methods involve administration of the amniotic fluid formulation in the form of aerosol droplets with size between about 1.5 µm to about 5 µm, preferably from about 2.5µm to about 3.5µm, inclusive, using apparatus such as high-efficiency vibrating mesh nebulizers.
Patent CA-3028144-A1 (CA)
Title: Gas atomization nozzle and gas atomization device
Inventor: HANADA TADAYUKI
IPC: B05B7/16
Filed: 2018-01-25
Abstract: The purpose of the present invention is to generate fine powder with less variation in particle size. Provided is a gas atomization nozzle comprising: a through-hole (3A) formed along a center line (C); a nozzle portion (3D) configured as a Laval nozzle, which is disposed along a periphery of the center line (C) and inclined at a predetermined angle (a) with respect to the center line (C); and a swirling motion imparting means for imparting a swirling flow around the center line (C) to gas emitted from the nozzle portion (3D).
Patent CA-3029449-A1 (CA)
Inventor: KUSIK MICHAEL
IPC: A47B88/988
Filed: 2017-04-28
Abstract: : A shelving system for storing and displaying bottles within a cellar. The shelving system includes at least one rack for supporting and displaying bottles, the least one rack being mountable onto a given wall of the cellar and being displaceable with respect to said given wall so as to be displaced in and out of the cellar along an operative directional axis. The shelving system also includes at least one recess provided about the at least one rack, each recess being positioned, shaped and sized for receiving a corresponding bottle, and each recess being disposed about the at least one rack, at an angle with respect to the operative directional axis of the at least one rack, so as to allow peripheral side surfaces of bottles resting on the at least one rack to face a front portion of the cellar.
Patent CA-3029542-A1 (CA)
Title: Acier pour porte-outil
Inventor: DAMM PETTER
IPC: C22C38/04
Filed: 2017-06-07
Abstract: Cette invention concerne un acier pour porte-outil. L'acier comprend les composants principaux suivants (en % en poids) : 0,07 à 0,13 de C, 0,10 à 0,45 de Si, 1,5 à 3,1 de Mn, 2,4 à 3,6 de Cr, 0,5 à 2,0 de Ni, 0,1 à 0,7 de Mo, 0,001 à 0,06 d'Al, moins de 0,003 de S. L'acier a une microstructure bainitique comprenant jusqu'à 20 % en volume d'austénite retenue et jusqu'à 20 % en volume de martensite.
Patent CA-3030008-A1 (CA)
Inventor: MCMICHAEL JUSTIN
IPC: H03M7/30
Filed: 2017-07-06
Abstract: The disclosure is directed at a method of data compression using inferred data. By determining the number of leading zeroes for each data structure, a general header presenting all leading zeros can be generated and use to compress the data.
Patent CA-3033361-A1 (CA)
Title: Systemes et procedes de stockage d'un fichier de contenu multimedia pour transmission a partir d'une source differente
Inventor: Rosqvist Sean William
IPC: H04N5/76
Filed: 2017-08-16
Abstract: La présente invention porte sur des systèmes et des procédés permettant de déterminer efficacement qu'un actif multimédia programmé pour être stocké à partir d'une source de contenu a été reprogrammé à une autre source de contenu. Par exemple, en examinant le contenu de paquets de données reçus avec un actif multimédia qui identifient l'actif multimédia actuellement reçu (par exemple, un champ dans une table d'informations d'événement), une application de guidage multimédia exécutée sur un boîtier décodeur ou un autre dispositif d'équipement utilisateur peut déterminer en temps réel que l'actif multimédia programmé pour être stocké n'est pas actuellement transmis à partir de la source de contenu planifiée à l'origine. En réponse à la détermination selon laquelle l'actif multimédia n'est pas disponible à partir de la source de contenu planifiée à l'origine, l'application de guidage multimédia peut rechercher, par l'intermédiaire de paquets reçus, d'autres sources de contenu afin de déterminer une source de contenu à partir de laquelle l'actif multimédia a été reprogrammé, et stocker l'actif multimédia à partir de cette source de contenu.
Patent CA-3034148-A1 (CA)
Title: Composes de sulfonimidoylpurinone substitues dans la position 7 pour le traitement et la prophylaxie d'infection virale
Inventor: GAO LU
IPC: C07D473/24
Filed: 2017-08-28
Abstract: La présente invention concerne des composés de formule (I), dans laquelle R1, R2 et R3 sont tels que décrits ici, et leurs promédicaments ou leur sel, énantiomère ou diastéréoisomère pharmaceutiquement acceptables de ceux-ci, des compositions comprenant les composés et des procédés d'utilisation des composés comme agonistes de TLR7 pour le traitement et la prophylaxie d'infections virales.
Patent CA-3035076-A1 (CA)
Inventor: DUPERE JONATHAN ROBERT BARCLAY
IPC: C12N5/078
Filed: 2017-08-28
Abstract: The present invention refers to a cell suspension of autologous or allogeneic, preferably autologous, adult bone marrow-derived white blood cells, preferably derived from the crest of the ilium (or iliac crest), enriched for mononuclear cells, meaning more than 25% of the white blood cells (WBCs) present in the cell suspension are mononuclear cells, and comprising: A.Mononuclear cells (MNC) selected from the list comprising or consisting of: i. A population of Lymphocytes; ii. A population of Monocytes; and iii. A population of Hematopoietic stem cells expressing CD34; and wherein the cell suspension further comprises: B.Granulocytes; for use in the treatment or amelioration of lower extremity peripheral artery disease.
Patent CA-3035712-A1 (CA)
Title: Composes de 8-(azetidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridinyle, compositions et procedes d'utilisation de ceux-ci
Inventor: GOODACRE SIMON CHARLES
IPC: A61K31/437
Filed: 2017-09-02
Abstract: L'invention concerne des composés de formule (I) et (II), ou un stéréoisomère, un tautomère, un solvate, un promédicament ou un sel de ceux-ci, et des procédés d'utilisation en tant qu'inhibiteurs de Janus kinase.
Patent CA-3036313-A1 (CA)
Title: Compositions comprising a cannabinoid receptor binding ligand
Inventor: GUNTHER BERNHARD
IPC: A61K31/025
Filed: 2017-09-27
Abstract: The present invention provides a pharmaceutical composition comprising: a) a therapeutically effective amount of at least one cannabinoid receptor binding ligand, and b) a liquid vehicle comprising at least one semifluorinated alkane; as well as the use of such pharmaceutical compositions as a medicament.
Patent CA-3036579-A1 (CA)
Title: Process for the preparation of syndiotactic 1,2-polybutadiene in the presence of a catalytic system comprising a pyridyl iron complex
Inventor: SOMMAZZI ANNA
IPC: C08L9/00
Filed: 2017-10-20
Abstract: Process for the preparation of syndiotactic 1,2-polybutadiene comprising polymerising 1,3-butadiene in the presence of a catalytic system comprising: - at least one pyridyl iron complex having the general formula (I), in which: - R1 represents a hydrogen atom; or a methyl group; - R2 represents a hydrogen atom; or is selected from linear or branched C1-C10, preferably C1-C3, alkyl groups; - X, identical or different to one another, represent a halogen atom such as, for example, chlorine, bromine, iodine; or are selected from linear or branched, C1-C20, preferably C1-C15, alkyl groups, -OCOR3 groups or -OR3 groups in which R3 is selected from linear or branched C1-C20, preferably C1-C15, alkyl groups; - n is 2 or 3; - at least one aluminoxane having the general formula (II), (R4)2-AI-O-[-AI(R5)-O-]m-AI-(R6)2 (ll) in which R4, R5 and R6, identical or different to one another, represent a hydrogen atom, or a halogen atom such as, for example, chlorine, bromine, iodine, fluorine; or are selected from linear or branched C1-C20 alkyl groups, cycloalkyi groups, aryl groups, said groups being optionally substituted with one or more silicon atoms or germanium; and m is an integer ranging from 0 to 1000; in which the molar ratio between the aluminium present in the aluminoxane having the general formula (II) and the iron present in the pyridyl iron complex having the general formula (I) is ranging from 5 to 20, preferably ranging from 8 to 12.
Patent CA-3041478-A1 (CA)
Inventor: PIEPENBURG OLAF
IPC: C12Q1/6844
Filed: 2005-04-11
Abstract: This disclosure describes related novel methods for Recombinase-Polymerase Amplification (RPA) of a target DNA that exploit the properties of recombinase and related proteins, to invade double-stranded DNA with single stranded homologous DNA permitting sequence specific priming of DNA polymerase reactions. The disclosed methods have the advantage of not requiring thermocycling or thermophilic enzymes, thus offering easy and affordable implementation and portability relative to other amplification methods. Further disclosed are conditions to enable real-time monitoring of RPA reactions, methods to regulate RPA reactions using light and otherwise, methods to determine the nature of amplified species without a need for gel electrophoresis, methods to improve and optimize signal to noise ratios in RPA reactions, methods to optimize oligonucleotide primer function, methods to control carryover contamination, and methods to employ sequence-specific third "specificity" probes. Further described are novel properties and approaches for use of probes monitored by light in dynamic recombination environments.
Patent CA-3043843-A1 (CA)
Title: Habitation block and method for producing thermal insulation
Inventor: MALLINOWSKI IVAN
IPC: E04B1/348
Filed: 2017-11-15
Abstract: A residential block is disclosed comprising residential storeys arranged one above the other, wherein at least one of the residential storeys comprises residential units (1) adjacent to each other having: an outer shell (2) consisting of a cuboid container with a bottom surface (6), a cover (7), up to two lateral walls (8) and up to two end walls (9, 10); a cuboid interior (3) with an edge length of at least 2 m in each case, an accessible floor (12) with footfall sound absorption (17), a ceiling (13) and up to four room walls (14, 15); an intermediate space (4) formed between the cover (7) and the walls (8), and also between the ceiling (13) and the room walls (14); and a monolithic thermal insulation (5) made of polyurethane hard foam in the intermediate space (4). A method for producing a thermal insulation (5) of this kind is also disclosed.
Patent CA-3045795-A1 (CA)
Inventor: LEONE-BAY ANDREA
IPC: A61K9/00
Filed: 2017-10-06
Abstract: Plant-based medicinal compounds or nutritional supplements in various carrier combinations are described. The carriers can include N-acylated fatty amino acids, penetration enhancers, and/or various other beneficial carriers. The plant-based composition/carrier combinations can create administration benefits.
Patent CA-3047053-A1 (CA)
Inventor: JONES IAN KEVIN
IPC: A01N43/90
Filed: 2017-12-15
Abstract: The present invention relates to solid forms of the insecticide of formula I: I, compositions comprising the solid forms and methods of teir use as insecticides.