baber/WOPTO huggingface dataset:
Patent CA-3029806-A1 (CA)
Inventor: SHOWALTER TIMOTHY NORMAN
IPC: A61K51/12
Filed: 2017-07-07
Abstract: The invention relates generally to methods of using a thiol -Michael addition hydrogel for providing intracavitary brachytherapy and/or displacing tissue and organs. The thiol-Michael addition hydrogel may be used as a packing material and an attenuation material for intracavitary brachytherapy applications. The invention also relates generally to a brachytherapy applicator, which may be used in conjunction with the thiol- Michael addition hydrogel and methods thereof. The invention also relates to a kit comprising at least one container containing the precursor materials of the thiol-Michael addition hydrogel.
Patent CA-3031082-A1 (CA)
Title: Proteines bispecifiques et leurs procedes de preparation
Inventor: KIM HOEON
IPC: C07K16/46
Filed: 2017-07-19
Abstract: La présente invention concerne une protéine bispécifique et son procédé de préparation, et plus spécifiquement, à une protéine bispécifique ayant une pureté d'hétérodimères qui est préparée par l'introduction d'une mutation dans une chaîne lourde et/ou une chaîne légère afin d'augmenter ainsi le taux de formation d'hétérodimère entre une chaîne lourde (domaine CH3 ou Fc) et une chaîne lourde (domaine CH3 ou Fc) et augmenter le taux de formation de dimère entre des chaînes ciblant le même matériau entre une chaîne lourde (domaine CH1) et une chaîne légère. La protéine bispécifique selon la présente invention est utile dans divers domaines tels que le traitement du cancer, la régulation du signal, le diagnostic, etc.
Patent CA-3031458-A1 (CA)
Inventor: LI QINGENG
IPC: C07D295/192
Filed: 2017-07-24
Abstract: Provided are a vortioxetine analogue as shown in formula I or a polymorph or a solvate thereof, a composition and a kit comprising the analogue, polymorph or solvate, the use of the analogue, polymorph or solvate in the preparation of a drug for treating depression, a method for preparing the analogue, and intermediates in the method.
Patent CA-3031777-A1 (CA)
Title: Crystalline form of olaparib
Inventor: REY ALLAN W
IPC: C07D237/32
Filed: 2019-01-28
Abstract: The present invention provides a novel crystalline form of Olaparib comprising Olaparib and benzyl alcohol, compositions thereof, and the use of this crystalline form in the treatment of cancers, such as germline BRCA-mutated (gBRCAm) advanced ovarian cancer.
Patent CA-3039374-A1 (CA)
Title: Machine learning classifier and prediction engine for artificial intelligence optimized prospect determination on win/loss classification
Inventor: SCHWARM ALEXANDER T
IPC: G06Q10/00
Filed: 2017-10-04
Abstract: Embodiments of a system and method for identifying and prioritizing company prospects by training at least one classifier on client company win/loss metrics. One or more classifiers can be trained on a training database compiled from company win/loss database for a client and firmographic data from a robust business entity database. Once trained, the system can employ Artificial Intelligence powered by the trained classifiers to classify and output customized prospect lists of thousands of profiled and scored companies that the AI has determined are likely targets for specific marketing and sales. The AI can also ingest databases of client targets and classify and score them based on the custom-trained classifier.
Patent CA-3039550-A1 (CA)
Inventor: SIMONEAU CORDELL
IPC: B01D21/24
Filed: 2017-10-06
Abstract: There is provided a material treatment apparatus. The material treatment apparatus includes a first compartment. The first compartment includes an inlet for receiving supply of slurry material, and a first material conduction space for conducting flow of the supplied slurry material in a downwardly direction. A second compartment is also provided including a second material conduction space for receiving a first intermediate material of the supplied slurry material and conducting the first intermediate material in an upwardly direction. A baffle is provided for interfering with conducting of the supplied slurry material from the first material conduction space to the second material conduction space. A turbulent flow mitigation device is disposed within the first compartment and configured to, upon interaction with the supplied slurry material, to effect adjustment to the flow characteristics of the supplied slurry material to generate a downwardly flowing flow characteristic-adjusted slurry material, wherein the flow characteristics of the supplied slurry material are transformed from turbulent flow to laminar flow. The turbulent flow mitigation device is disposed, relative to the baffle, such that the baffle directs the downwardly flowing flow characteristic-adjusted slurry material to a space below the first baffle. The first material conducting space is fluidly coupled, below the baffle, to the second material conduction space, such that the first intermediate material fraction of the downwardly flowing flow characteristic-adjusted slurry material is conducted to the second material conduction space from below the baffle. A collection region is disposed below the first and second compartments for collecting a separated solids-comprising fraction that has separated, by gravity settling, from the supplied slurry material.
Patent CA-3041406-A1 (CA)
Inventor: SEEGER MARKUS
IPC: C07K16/12
Filed: 2017-10-30
Abstract: The invention relates to a method for identifying and quantifying a polypeptide from a library of polypeptides. The method comprises the steps of: 1 - providing a polypeptide library and a detection tag library, 2 - generating a nested library comprising the polypeptides and the detection tags, 3 - sequencing the nested library, 4 - selecting a member of the nested library in one or several selection steps that are independent of a physical genotype-phenotype linkage, 5 - isolating the detection tag from the selected polypeptide, 6 - identifying and quantifying the detection tag by mass spectrometry, 7 - obtaining the sequence of the selected polypeptide. The invention also relates to a collection of polypeptides, a collection of detection tags, and a collection of plasmid vectors.
Patent CA-3042808-A1 (CA)
Title: Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
Inventor: LANDER CYNTHIA
IPC: A61P11/00
Filed: 2012-04-12
Abstract: A pharmaceutical composition for use in the treatment of a disease, condition, or pathologic process characterized by aberrant fibroblast proliferation and extracellular matrix deposition in a tissue of a subject, wherein the pharmaceutical composition comprises a therapeutic amount of a polypeptide of the amino acid sequence YARAAARQARAKALARQLGVAA (SEQ ID NO: 1) or a functional equivalent thereof, and a pharmaceutically acceptable carrier thereof, and wherein the therapeutic amount is effective to reduce the fibroblast proliferation and extracellular matrix deposition in the tissue of the subject.
Patent CA-3045602-A1 (CA)
Title: Milking system
Inventor: MOSTERT GERARD
IPC: A01J5/013
Filed: 2017-11-27
Abstract: A milking system for milking a dairy animal comprises a milking cup, a measuring chamber which is in flow communication with the milking cup for the obtained milk, and having a sensor system arranged therein or thereon for measuring at least one property of the milk. The sensor system comprises at least three optical sensor devices, each configured to measure values of a property of the milk, and a sensor control unit for actuating the sensor system and for processing the measured values. The sensor control unit is configured to repeatedly select one of the sensor devices in a targeted manner, wherein each sensor device is selectable, wherein at least two of the optical sensor devices are identical, and wherein the sensor system is configured to in each case measure the local value of the property of the milk at the location of the selected sensor device using the selected sensor device, and to determine a value of the at least one property of the milk in the measuring chamber on the basis of the values measured locally by the plurality of sensor devices. The sensor system may thus reliably determine the value of the milk property of the entire milk in the measuring chamber on the basis of the plurality of locally measured values of the milk property.
Patent CA-3045658-A1 (CA)
Inventor: LAURENT BOYD ANTHONY
IPC: C09K8/54
Filed: 2017-12-01
Abstract: La présente invention concerne de manière générale des compositions et des procédés pour inhiber la corrosion au niveau d'une surface dans la production, le transport, le stockage et la séparation de pétrole brut et de gaz naturel.
Patent CA-3046447-A1 (CA)
Inventor: COUPLAND JOHN
IPC: E02D5/14
Filed: 2018-03-20
Abstract: The invention relates to apparatus and methods for constructing walls, in particular concrete embedded retaining walls such as diaphragm walls, comprising one or more panels, and walls so constructed. In particular the invention relates to apparatus, methods and walls, in particular concrete embedded retaining walls such as diaphragm walls, and kits (comprising)a guideway. In one aspect there is provided aguideway tube(32)for casting into a concrete panel (24, 26) along a height of a face of the concrete panel (24, 26),comprising:an elongate guideway track (50) comprising at least one elongate side wall (33) and an elongate slot (44) along the at least one elongate side wall (33), the elongate slot (44) having a first width (W1); and, an elongate closure panel (70) comprising: a rear panel portion (72) configured to close the elongate slot (44) enclosing an elongate internal volume(V1), and,a front panel portion (74) of a second width (W2) greater than the first width (W1). Preferably the rear panel portion (72) is a close fit within elongate slot (44) sufficient to resist the ingress of slurry and concrete. Preferably the rear panel portion (72) is configured to engage the elongate slot (44) in a manner configured to resist compression forces.The invention also describes a guideway tube, an apparatus, a guideway track, a method, a wall, and a kit.
Patent CA-3049332-A1 (CA)
Title: Method and device for detecting defects in the closure of encapsulated vials
Inventor: BOIRA BONHORA JORDI
IPC: G01N21/90
Filed: 2019-07-11
Abstract: Method and device for detecting defects in the closure of encapsulated vials Method for detecting defects in the closure of encapsulated vials, comprising the following steps: a) Scanning a profile of the capsule and of the vial using a profilometer, thus obtaining a point cloud. b) From the point cloud obtained in the previous step, calculating at least one of the following parameters: i.          Diameter or radius of the closure circumference of the capsule. ii.     Angle of intersection between the lower skirt and the side of the capsule. iii.     Length of the lower skirt. iv.     Distance from the end of the lower skirt to the neck of the vial. c) Determining whether any of said parameters calculated in the previous step exceeds a predetermined limit value. And device for detecting defects in the closure of encapsulated vials, comprising a profilometer configured to scan a profile of the capsule and of the vial and a control device configured to execute a method such as that described earlier.
Patent CA-3050320-A1 (CA)
Title: Printing process and system
Inventor: GOREDEMA ADELA
IPC: B29C64/264
Filed: 2019-07-22
Abstract: Disclosed herein is a printing method and system for forming a three dimensional article. The method includes depositing a UV curable composition and applying UV radiation to cure the UV curable composition to form a 3D structure. The method includes depositing a conductive metal ink composition on a surface of the 3D structure and annealing the conductive metal ink composition at a temperature of less than the glass transition temperature of the UV curable composition to form a conductive trace on the 3D structure. The method includes depositing a second curable composition over the conductive trace; and curing second curable composition to form the 3D printed article having the conductive trace embedded therein.
Patent CA-3053248-A1 (CA)
Title: Amelioration de resistance initiale de ciments
Inventor: SILVA DENISE A
IPC: C04B40/00
Filed: 2017-10-25
Abstract: L'invention concerne un procédé de fabrication d'une composition de ciment, consistant à broyer un clinker de ciment et un agent d'amélioration de résistance, ce qui permet de produire une poudre cimentière hydraulique, l'agent d'amélioration de résistance étant présent dans la poudre cimentière hydraulique à une teneur de 0,001 % à 0,09 % sur la base du poids sec de la poudre cimentière hydraulique. L'agent d'amélioration de résistance est un composé représenté par la formule structurale suivante (I). L'invention décrit les définitions des variables R1, R2 et R3 de même que R10, R20 et R30.
Patent CA-3054125-A1 (CA)
Title: Computer controlled brake parking brake control system
Inventor: WRIGHT ERIC C
IPC: B60T13/66
Filed: 2017-02-21
Abstract: A computer controlled locomotive brake (CCB) configured for setting and releasing the automatic parking brakes of the railcars of a train. The CCB may initially recharge the brake pipe to a pressure slightly less than the parking brake unlatch pressure. The CCB may then continue charging to this level until the brake pipe flow, measured at the CCB on the controlling locomotive and the brake pipe pressure on the last car, as measured by an end of train device, indicate that the pressure in the braking system reservoirs are substantively equal to the brake pipe pressure. Once the reservoirs are substantively charged, the CCB may complete the brake release and recharge by recharging the brake pipe pressure to its final charge so that all parking brakes are released and the train has sufficient braking system recharge to safely control movement of the train.
Patent CA-3056811-A1 (CA)
Inventor: PINAULT PHILIPPE
IPC: A61L2/00
Filed: 2018-03-20
Abstract: Dispositif de traitement thermique de grumes La présente invention concerne un dispositif de traitement thermique destiné à être associé à un conteneur (3) chargé de grumes, comportant une conduite (1) d'arrivée de vapeur d'eau sous pression. Ledit dispositif de traitement thermique est particulier en ce qu'il comporte au moins un, de préférence deux, tube (2) sensiblement rectiligne, muni d'une pluralité d'ouvertures réparties sur sa longueur et sur sa circonférence, ledit au moins un tube (2) étant destiné à être introduit depuis l'arrière dans ledit conteneur (3) chargé de grumes, et à être alimenté par ladite vapeur d'eau sous pression. La présente invention concerne également un procédé pouvant être mis en uvre par le moyen d'un dispositif selon l'invention.
Patent CA-3058602-A1 (CA)
Title: Production automatisee d`information cartographique a partir d`images interdependantes
Inventor: COLBURN ALEX
IPC: G09B29/00
Filed: 2019-10-09
Abstract: Il est décrit des techniques dutilisation dappareils informatiques aux fins de réalisation dopérations automatisées en vue de générer des informations cartographiques au moyen dimages dune région définie reliées entre elles. Les techniques en question servent également à utiliser les informations cartographiques dautres manières automatisées. Dans certains cas au moins, la région définie comprend lintérieur dun bâtiment à plusieurs chambres, et les informations générées comprennent une carte détage du bâtiment, comme celles obtenues par analyse automatique de plusieurs images panoramiques ou dautres images capturées à partir de divers endroits à lintérieur du bâtiment. Dans au moins certains des cas décrits, la génération se fait également en labsence dinformations détaillées quant aux distances entre les points de vue à partir desquelles les images sont capturées et des murs ou autres objets dans le bâtiment environnant. La carte détage et les autres informations cartographiques générées peuvent servir de différentes façons, notamment le guidage dappareils (comme les véhicules autonomes) et laffichage dau moins un appareil utilisateur dans une interface utilisateur graphique.
Patent CA-3059278-A1 (CA)
Inventor: MCGEER PATRICK L
IPC: C07C66/00
Filed: 2018-05-30
Abstract: L'invention porte sur une méthode de traitement de la cachexie. La méthode comprend l'administration à un être humain en ayant besoin d'une quantité efficace d'un inhibiteur du complément. L'inhibiteur du complément peut être un dimère d'acide acétyl salicylique, y compris l'acide 5,5'-méthylènebis(acide 2-hydroxybenzoïque), 4,4'-diacétoxy-1,1 biphényl-3,3' dicarboxylique ou un sel pharmaceutiquement acceptable de celui-ci. L'inhibiteur du complément peut être de l'acide aurine tricarboxylique, de l'acide aurine quadracarboxylique, de l'acide aurine pentacarboxylique, de l'acide aurine hexacarboxylique, des combinaisons de ceux-ci, et des sels pharmaceutiquement acceptables de ceux-ci. L'inhibiteur du complément peut être un promédicament ester des composés précédents.
Patent CA-3059706-A1 (CA)
Inventor: BREEN SCOTT M
IPC: B21J13/04
Filed: 2019-10-23
Abstract: A pilot assembly having a shaped portion and a shaped fastener relief for attachment to a die. The pilot assembly includes a fastener with a shaped washer that engages the shaped fastener relief to permit installation and removal of the pilot from the die. The shaped portion of the pilot assembly helps to locate and center the stock down the pilot assembly toward the die.
Patent CA-3060042-A1 (CA)
Title: Soybean variety 5pdkt23
Inventor: KALVIG ANDREA BETH
IPC: A23K10/30
Filed: 2019-10-24
Abstract: A novel soybean variety, designated 5PDKT23 is provided. Also provided are the seeds of soybean variety 5PDKT23, cells from soybean variety 5PDKT23, plants of soybean 5PDKT23, and plant parts of soybean variety 5PDKT23. Methods provided include producing a soybean plant by crossing soybean variety 5PDKT23 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PDKT23, methods for producing other soybean varieties or plant parts derived from soybean variety 5PDKT23, and methods of characterizing soybean variety 5PDKT23. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PDKT23 are further provided.
Patent CA-3060814-A1 (CA)
Inventor: TAYLOR JON
IPC: A61B90/00
Filed: 2006-08-10
Abstract: La présente invention décrit des modes de réalisation modèles dun dispositif de biopsie à échantillonnage multiple et introduction unique. Elle décrit en outre des modes de réalisation modèles dun dispositif déchantillonnage multiple à introduction unique présentant des marqueurs intégrés.
Patent CA-3061089-A1 (CA)
Title: Wireless communication method and device
Inventor: YANG NING
IPC: H04W72/04
Filed: 2017-04-27
Abstract: Embodiments of the present application provide a wireless communication method and device, which can improve communication performance. The method comprises: a terminal device determines the data amount of currently cached-uplink data and information about a target type of data in the currently-cached uplink data; and the terminal device sends a first message to a network device, the first message being used for indicating the data amount of the currently-cached uplink data and the information about the target type of data.
Patent CA-3062800-A1 (CA)
Inventor: LEBEDYEVA IRYNA
IPC: A61K31/221
Filed: 2018-05-07
Abstract: L'invention concerne des modes de réalisation de sels de créatine et de créatine éthyl-ester (CEE) dans lesquels l'anion est un modificateur de goût artificiel (sans saccharide). Ces composés représentent des solides ou des semi-solides non hygroscopiques, blancs, stables qui peuvent se dissoudre facilement dans l'eau et dans des solutions tampon. La synthèse de nouveaux sels de créatine faisant appel à des solvants sans danger pour l'environnement tels que l'éthanol conduit à la formation de produits en rendements quantitatifs avec du chlorure de sodium ou de potassium comme sous-produit. Les sels de créatine et de créatine alkyl-ester sont des composés au goût sucré stables qui sont plus agréables au goût pour le consommateur que la créatine ou des dérivés de celle-ci.
Patent CA-3063470-A1 (CA)
Inventor: ZIELKOWSKI AMANDA K
IPC: A45C1/04
Filed: 2018-05-21
Abstract: A system includes a portable locker including a container that may receive and store items and a first lock coupled to the container and that may lock the container to block access to the stored items. The first lock includes a detector that may receive a wireless signal, and receiving the wireless signal causes the first lock to lock or unlock. The system also includes a restraint coupled to the container and includes a second lock. The second lock may secure the portable locker to a rider of an amusement park ride.
Patent CA-3064750-A1 (CA)
Inventor: NOROUZIAN ANDREW
IPC: B65H75/20
Filed: 2019-12-12
Abstract: A reel includes a first flange, a second flange, and a plurality of segmented structures each including a plurality of links pivotably coupled to a bracket of the first flange by a first end pivot rod and to the a bracket of the second flange by a second end pivot rod. The plurality of links is configured to have a first stable arrangement and a second stable arrangement different from the first stable arrangement. In the first stable arrangement, the first flange and the second flange are separated by a first distance with the reel being configured to support a first maximum load of cable, while in the second stable arrangement, the first flange and the second flange are separated by a second distance less than the first distance with the reel being configured to support a second maximum load of cable less than the first maximum load of cable.
Patent CA-3066695-A1 (CA)
Title: Mounting element for production of a dental prosthesis, a prosthesis and method of manufacturing same
Inventor: HORNBECK JACQUES
IPC: B33Y80/00
Filed: 2018-06-19
Abstract: The present invention concerns a mounting element (2) for a dental prosthesis (1), the prosthesis (1) including at least one bridge, the mounting element (2) and prosthesis (1) being formed using 3D printing. The mounting element (2) has an axis (14) of elongation and comprises an engagement portion (15), for fixedly engaging the prosthesis (1) and an attachment portion (19), for enabling secure attachment of the prosthesis (1) to the jig (6) during machining. The mounting element (2) further comprises a registration portion (17) for aligning, in use, the prosthesis (1) in a precise position and/or orientation on a jig (6) during machining. The registration portion (17) comprises a tapering portion having a conically tapering outer surface (20). A method of fabricating a dental prosthesis (1) and a dental prosthesis (1) are also disclosed.
Patent CA-3070006-A1 (CA)
Title: Procede de lecture de donnees memorisees dans une memoire cache non volatile a l'aide d'un rdma
Inventor: TAO ZUOYO
IPC: G06F12/0868
Filed: 2018-09-28
Abstract: Des blocs de données sont mis en mémoire cache dans une mémoire cache persistante (mémoire cache NV) attribuée à partir d'une RAM non volatile (NVRAM). Les blocs de données peuvent faire l'objet d'un accès en leur emplacement dans la mémoire cache NV d'un élément informatique « source » par un autre élément informatique « distant » sur un réseau à l'aide d'un accès direct à la mémoire à distance (RMDA). Pour qu'un élément informatique distant accède au bloc de données dans la mémoire cache NV sur un élément informatique source, l'élément informatique distant nécessite l'adresse mémoire du bloc de données à l'intérieur de la mémoire cache NV. À cet effet, une table de hachage est mémorisée et maintenue dans une RAM sur l'élément informatique source. La table de hachage identifie les blocs de données dans la mémoire cache NV et spécifie un emplacement du bloc de données mis en cache dans la mémoire cache NV.