baber/WOPTO huggingface dataset:
Patent JP-3152440-B2 (JP)
IPC: C07D417/12
Filed: 1997-10-28
Granted: 2001-04-03
Abstract: Compound represented by the structural formula    <IMAGE>  I  or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or 3; b, d and e are independently 0, 1 or 2; R is H, C1-6 alkyl, -OH or C2-C6 hydroxyalkyl; A is an optionally substituted oxime, hydrazone or olefin; X is a bond, -C(O)-, -O-, -NR6-, -S(O)e-, -N(R6)C(O)-, -C(O)N(R6)- -OC(O)NR6-, -OC(=S)NR6-, -N(R6)C(=S)O-, -C(=NOR1)-, -S(O)2N(R6)-, -N(R6)S(O)2-, -N(R6)C(O)O- or -OC(O)-; T is H, phthalimidyl, aryl, heterocycloalkyl, heteroaryl, cycloalkyl or bridged cycloalkyl; Q is heteroaryl; R6a, R7a, R8a, R9a, R6 and R7 are H, C1-6 alkyl, C2-C6 hydroxyalkyl, C1-C6 alkoxy-C1-C6 alkyl, phenyl or benzyl; or R6 and R7, together with the nitrogen to which they are attached, form a ring; R9a is R6 or -OR6; Z is morpholinyl, optionally N-substituted piperazinyl, optionally substituted   <IMAGE>   or substituted   <IMAGE>   g is 0-3 and h is 1-4, provided the sum of h and g is 1-7; wherein aryl, heterocycloalkyl, heteroaryl, cycloalkyl and bridged cycloalkyl groups are optionally substituted; methods of treating asthma, cough, bronchospasm, imflammatory diseases, and gastrointestinal disorders with said compounds, and pharmaceutical compositions comprising said compounds are disclosed.
Patent JP-3488462-B2 (JP)
IPC: A43C11/16
Filed: 1993-12-27
Granted: 2004-01-19
Abstract: PCT No. PCT/DE93/01250 Sec. 371 Date Nov. 15, 1995 Sec. 102(e) Date Nov. 15, 1995 PCT Filed Dec. 27, 1993 PCT Pub. No. WO94/26138 PCT Pub. Date Nov. 24, 1994A shoe fastener with a rotary actuating element (35) that has a pulley (3) coupled thereto via a self-locking reduction gear which is in the form of an eccentric drive (10, 12). An unwinding gear is pivotally mounted in a housing (1) of the fastener and is formed of a disk (24) having a grooved outer catch rim (26). The unwinding gear can be fixed in any of several angular positions via a catch element (42) which can be released via a tension element (47) which, at the same time, can be used to pull open the shoe by lifting of a tongue or instep cover (55) of the shoe upon which the fastener is mounted.
Patent JP-3592330-B2 (JP)
IPC: C12N1/38
Filed: 1995-04-27
Granted: 2004-11-24
Abstract: The invention relates to the use of a phosphate glass as a phosphorous source in the media of high cell density bacterial fermentation processes in order to reduce metallophosphate precipitation reactions. The methods of the invention demonstrate a practical method for controlling levels of metallophosphate precipitation in both the nutrient media and the fermentor which also result in increased cell densities and are useful in a variety of high cell density bacterial fermentation processes.
Patent JP-4065556-B2 (JP)
IPC: A61K47/34
Filed: 1995-05-03
Granted: 2008-03-26
Abstract: The present invention relates to a composition for the modulated release of a biologically active agent. The composition comprises a biocompatible polymeric matrix, a biologically active agent which is dispersed within the polymeric matrix, and a metal cation component which is separately dispersed within the polymeric matrix, whereby the metal cation component modulates the release of the biologically active agent from the polymeric matrix. The present invention also relates to a method for modulating the release of a biologically active agent from a biocompatible polymeric matrix, comprising the steps of dissolving a biocompatible polymer in a solvent to form a polymer solution and also separately dispersing a metal cation component and a biologically active agent within the polymer solution. The polymer solution is then solidified to form a polymeric matrix, wherein at least a significant portion of the metal cation component is dispersed in the polymeric matrix separately from the biologically active protein, and whereby the metal cation component modulates the release of the biologically active agent from the polymeric matrix.
Patent JP-3787157-B2 (JP)
IPC: A61K48/00
Filed: 1996-04-26
Granted: 2006-06-21
Abstract: Fragments and an aggregate form of an endothelial cell proliferation inhibitor and methods of use therefor are provided. The endothelial proliferation inhibitor is a protein derived from plasminogen, or more specifically is an angiostatin fragment. The angiostatin fragments generally correspond to krinkle structures occurring within the endothial cell proliferation inhibitor. Angiostatin is also prepared in an aggregate form. The endothelial cell inhibiting activity of the angiostatin fragments and the aggregate angiostatin provide a means for inhibiting angiogenesis of tumors and for treating angiogenic-mediated disease.
Patent JP-3527746-B2 (JP)
IPC: A61M25/01
Filed: 1998-04-02
Granted: 2004-05-17
Abstract: A multi-leaflet bioprosthetic heart valve comprising a plurality of leaflets, wherein each of the leaflets has a measured deflection response within 0.030. inches of the other leaflets upon application of a load sufficient to stress each of the leaflets between 300 and 600 kPa. <IMAGE>
Patent ES-2245139-B2 (ES)
Title: Estructura laminar de caucho para ser utilizada en la produccion de losas de granulado o de particulas finas de material petreo aglutinadas mediante resina endurecible.
Inventor: TONCELLI LUCA
IPC: B32B25/10
Filed: 2000-11-28
Granted: 2007-03-16
Abstract: Se utilizan dos láminas de caucho para la producción de losas de granulado o de partículas finas de material pétreo aglutinadas mediante resina endurecible, estando provista una de dichas láminas, la inferior, de un borde que define la cavidad de depósito para una cantidad dosificada de la mezcla. Por lo menos la lámina inferior y preferentemente ambas láminas presentan una estructura que consiste en dos capas de caucho EPM o VKF o PU, entre las cuales está interpuesta o se introduce una capa de tela o tejido de material no deformable, tal como poliamida o poliéster, y la superficie de la lámina orientada hacia el exterior está compuesta de una capa similar de tela o tejido. La lámina compuesta se puede estabilizar dimensionalmente por medio de la aplicación de calor a una temperatura más elevada que la temperatura de trabajo.
Patent ES-2352493-B2 (ES)
Title: Tetina individualizada para lactantes con fisura palantina
Inventor: MARTINEZ ALVAREZ CONCEPCION
IPC: A61J11/00
Filed: 2009-07-17
Granted: 2012-08-02
Abstract: La presente invención se refiere a tetinas especialmente diseñadas para lactantes de cualquier especie con fisura palatina. La punta de estas tetinas es más larga que la de una tetina estándar y la cara palatina forma un ángulo diedro cuyo vértice está truncado formando una franja elevada que se acopla a la fisura del paladar del lactante impidiendo el paso de leche a la vía aérea, evitando así neumonías por aspiración y otras infecciones asociadas. La invención también se refiere al método para realizar estas tetinas mediante la obtención de un molde del paladar fisurado y la utilización de planchas de plástico termomoldeable y de una máquina de termovacío. Las tetinas individualizadas se pueden utilizar en la alimentación de bebés y de crías tanto de animales de compañía y de especial valor económico como de animales de experimentación, permitiendo crear un modelo de experimentación animal para el estudio de esta patología tan compleja.
Patent ES-2364734-B2 (ES)
Title: Célula solar sensibilizada por colorante y fotoánodo del mismo.
Inventor: LEE KUAN-WEI
IPC: C07D213/22
Filed: 2010-11-05
Granted: 2012-06-06
Abstract: Célula solar sensibilizada por colorante y
fotoánodo del mismo. 
     Se divulga una célula solar sensibilizada por
colorante, un fotoánodo del mismo y un procedimiento para fabricar
el mismo. El fotoánodo de la célula solar sensibilizada por
colorante de la presente invención se prepara mediante una capa
semiconductora porosa que absorbe dos clases de colorantes orgánicos
sensibilizados y un colorante orgánico sensibilizado se representa
por la fórmula (I) siguiente: 
     
       1 
     
     en la que, D_{1}, D_{2},
R_{1}, R_{2}, R_{3}, R_{4}, B y n se definen igual que en la
memoria
descriptiva. 
     Estas dos clases de colorantes orgánicos
sensibilizados presentan picos de absorción comparables, de forma
que el fotoánodo de la presente invención puede absorber el espectro
solar en un mayor rango de longitudes de onda.   
     Por lo tanto, la célula solar sensibilizada por
colorante que usa el fotoánodo de la presente invención presenta una
excelente eficacia de conversión fotoeléctrica.
Patent ES-2543038-B2 (ES)
Title: Método y sistema de localización espacial mediante marcadores luminosos para cualquier ambiente
Inventor: VILLAR BONET EUGENIO
IPC: G06T7/00
Filed: 2014-12-23
Granted: 2015-11-26
Abstract: Método y sistema de localización espacial de un objetivo (10) en un entorno (11) tridimensional que comprende al menos un marcador luminoso comprendiendo:#- una cámara estéreo (12) para capturar una primera trama de imagen en un instante actual y una segunda trama de imagen en un instante anterior;#- un dispositivo de medida de ángulos (13) para obtener un ángulo de giro del objetivo (10);#- un procesador de señales (14) con acceso a una memoria (15) que almacena entre otros un radio del, al menos un, marcador detectado en un instante de tiempo actual n y en un instante de tiempo anterior n-1 configurado para calcular unas coordenadas (x{sub,i}, y{sub,i}) del objetivo (10) en un instante de tiempo i como sigue:#- si el ángulo de giro en el instante de tiempo actual y en el instante de tiempo anterior son distintos, (x{sub,n}, y{sub,n}) = (x{sub,n-1}, y{sub,n-1);#- si las dos tramas de imagen son iguales, (x{sub,n}, y{sub,n}) = (x{sub,n-1}, y{sub,n-1});#- en otro caso:#- si los radios son iguales y hay varios marcadores, (x{sub,n}, y{sub,n}) se calculan mediante triangulación usando ambas tramas de imagen;#- si los radios son distintos y hay varios marcadores, (x{sub,n}, y{sub,n}) se calculan mediante triangulación usando una sola trama de imagen;#- si los radios son distintos y hay un único marcador, (x{sub,n}, y{sub,n}) se calculan mediante geometría estéreo;#- si los radios son iguales y hay un único marcador, (x{sub,n}, y{sub,n}) se calculan usando coordenadas de imagen del marcador en el instante actual y en el anterior.
Patent IE-S86406-B2 (IE)
Title: A ladder attachment for supporting a paint can on a ladder
Inventor: COLLINS LONÁN
IPC: E06C7/00
Filed: 2012-01-11
Abstract: The device is a self-levelling paint can holder that can be used on any ladder with hollowed rungs. It has a hollowed receiving means for a paint can but it is adaptable so tools or cleaning materials can be held in it. A rod extends out from the top of the rim of the paint can receiving bucket which will slot through the rung of a ladder. From the point of intersection of the rod and the main body, a paint brush holder of the same material as the rest of the body extends upwards about 5cm, at the top a magnet is fixed for the purpose of holding a paint brush.
Patent IE-S86918-B2 (IE)
Title: Device for producing a monofilament twisted about its longitudinal axis
Inventor: Michael Müller
IPC: D01D5/00
Filed: 2018-02-02
Abstract: A device (1) for producing a monofilament (2) twisted about its longitudinal axis comprises a twisting device (3), which is configured to twist an untwisted monofilament (4) under tensile stress about its longitudinal axis, in order to produce the monofilament (2) twisted about its longitudinal axis, and a heating device (5) which is configured to heat the monofilament before, after and/or during the twisting. <Figure 1>
Patent AU-2001229957-B2 (AU)
Title: Piston engine
Inventor: LEHOFER GERHARD
IPC: F16J15/16
Filed: 2001-02-15
Granted: 2004-07-08
Abstract: The internal combustion motor has a gearing between the pistons and the crankshaft with a swing lever (13,18) on a center pivot axis (14,20) in a gear housing (25). A rotating roller (15,19) is at the lever ends, on axes at right angles to the lever swing axis, to ride on a path (16,24) at the shaft (17) between them. The ends of the levers are linked to the pistons (7-10) by connecting rods (12).
Patent AU-2001236937-B2 (AU)
Title: Seamed industrial fabrics
Inventor: SENELLART JEAN
IPC: D21F7/08
Filed: 2001-02-12
Granted: 2005-11-10
Abstract: An industrial fabric (20) is woven from machine-direction (MD) (24) and cross-machine-direction (CD) yarns (22), wherein the MD yarns (24) are multicomponent yarns having a plurality of individual strands and at least one thermofusible strand of a thermoplastic material. The at least one thermofusible strand of a thermoplastic material has a melting point lower than that of the individual strands of the multicomponent yarn. Upon application of a heat treatment, the multicomponent yarns are stiffened and the individual strands thereof are held together by the thermoplastic material of the at least one thermofusible strand.
Patent AU-2001277922-B2 (AU)
Title: Polycaprolactone adhesive composition
Inventor: TAKAMATSU YORINOBU
IPC: C09J201/00
Filed: 2001-07-19
Granted: 2007-03-22
Abstract: An adhesive composition having (i) a tackifying polymer and (ii) a crystalline polymer, such that the content of the tackifying polymer is from 55 to 95 wt. % based on the whole weight of the composition, and the content of the crystalline polymer is from 4 to 40 wt. % based on the whole weight of the composition, where the said crystalline polymer comprises polycaprolactone, and the tackifying polymer comprises a polymer that is compatible with said polycaprolactone when the composition is heated to the melting point of the polycaprolactone and is crosslinked.
Patent AU-2001288456-B2 (AU)
Title: Light-stabilized $I(in vivo) stain composition and method of manufacture
Inventor: BURKETT DOUGLAS D
IPC: C09B67/00
Filed: 2001-08-28
Granted: 2008-01-31
Abstract: Photochemical demethylation reactions in solutions of thiazine dyes, in which the dye molecules act as both sensitizer and substrate, are reduced by quenching triple-state dye molecules, returning them to the unreactive ground state.
Patent AU-2001294049-B2 (AU)
Title: Extraction method
Inventor: WILLIAMS DAVID MICHAEL
IPC: A61K36/58
Filed: 2001-10-15
Granted: 2006-09-21
Abstract: There is disclosed a method for treating a source of azadirachtin: (a) dissolving said sample in an organic polar solvent; (b) combining the solution of step (a) with an organic non-polar solvent to form a single phase containing the said solvents and dissolved sample; (c) treating said single phase of step (b) with an aqueous salt solution to form an aqueous phase and a phase containing the organic non-polar solvent; and (d) recovering one or other or both of the aqueous phase and the phase containing the organic polar solvent.
Patent AU-2002223168-B2 (AU)
Title: Animal box with detecting means
Inventor: LINDVALL TOMMY
IPC: A01K1/02
Filed: 2001-11-26
Granted: 2005-11-24
Abstract: A livestock pen with ends and long sides for permanently restricting the freedom of movement of animals kept therein. The livestock pen contains a moving, endless belt that supports all the weight of the animals. The belt is arranged to move from an inlet end towards an outlet end. An outlet end panel forms a gap between the belt and the outlet end panel's lowermost transverse member. At the belt's outlet end, a sensing means, when actuated, stops any ongoing belt movement. An additional aspect relates to a method for stopping the movement of an endless belt in a livestock pen, whereby a sensing means registers when a part of an animal is in a restricted area of the livestock pen. A signal from the sensing means then stops the belt's drive mechanism.
Patent AU-2002230589-B2 (AU)
Title: Fast dissolving tablet
Inventor: LI VINCENT H
IPC: A61K9/20
Filed: 2001-12-04
Granted: 2005-11-10
Abstract: The present invention relates to processes for the preparation of tablets which dissolve rapidly in the mouth and provide an excellent mouthfeel. The tablets of the invention comprise a compound which melts at about 37° C. or lower, have a low hardness, high stability and generally comprise few insoluble disintegrants which may cause a gritty or chalky sensation in the mouth. Convenient and economically feasible processes by which the tablets of the invention may be produced are also provided.
Patent AU-2002301199-B2 (AU)
Title: Strapping machines with improved refeed
Inventor: BRUZZESI KEVIN A
IPC: B65B13/06
Filed: 2002-09-25
Granted: 2007-12-20
Abstract: A strapping machine for positioning a strapping material (S) around an associated load (L) and sealing the strapping material to itself around the load (L), includes a frame (12), a feed assembly (26,28) mounted to the frame for feeding, retracting and automatically refeeding the strapping material, a guide (16) configured to receive the strapping material (S) from the feed assembly (26,28), and a strapping head (20) configured to receive the strapping material (S) from the feed assembly (26,28) via the guide (16) and to position the strapping material (S) around the load (L) and seal the strapping material to itself around the load (L). The feed assembly includes one and only one pair of reversible feed elements (26,28) and a drive (18). The machine includes a controller (112) operably connected to the drive (18). The one and only one pair of reversible feed elements (26,28) are configured to automatically feed, retract and refeed the strapping material (S) upon an appropriate signal from the controller (112). <IMAGE>
Patent AU-2002357245-B2 (AU)
Title: Carbide and nitride ternary ceramic glove and condom formers
Inventor: COX RICHARD L
IPC: C04B35/565
Filed: 2002-12-16
Granted: 2008-01-24
Abstract: A slip-cast article former containing ternary ceramics, particularly of carbide and nitride materials, having the formula M<SUB>n+1</SUB>AX<SUB>n</SUB>(MAX), where M is a transition metal, A is an element from Groups IA and IVA of the periodic table, X is nitrogen or carbon and n is 1, 2, or 3. The ternary ceramic article may be a glove or condom former. A process for making a ternary ceramic article employing a slip cast method.
Patent AU-2002360242-B2 (AU)
Title: Parallel, individually addressable probes for nanolithography
Inventor: BULLEN DAVID ANDREW
IPC: H01L21/027
Filed: 2002-07-26
Granted: 2007-11-01
Abstract: A microfabricated probe array for nanolithography and process for designing and fabricating the probe array. The probe array consists of individual probes that can be moved independently using thermal bimetallic actuation or electrostatic actuation methods. The probe array can be used to produce traces of diffusively transferred chemicals on the substrate with sub-1 micrometer resolution, and can function as an arrayed scanning probe microscope for subsequent reading and variation of transferred patterns.
Patent AU-2002366430-B2 (AU)
Title: Human DR4 antibodies and uses thereof
Inventor: KIM KYUNG JIN
IPC: A61P43/00
Filed: 2002-06-29
Granted: 2008-09-18
Abstract: Human Death Receptor 4 (DR4) antibodies are provided. The human DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided.
Patent AU-2003202349-B2 (AU)
Title: Methods and apparatus for re-establishing communication for a wireless communication device after a communication loss in a wireless communication network
Inventor: MUSA SARMAD K
IPC: H04L12/56
Filed: 2003-01-23
Granted: 2008-07-10
Abstract: Several related methods and apparatus for re-establishing communication for a wireless communication device after a communication loss between the wireless device and a wireless communication network are disclosed. In one illustrative example, the wireless network broadcasts identifiers of wireless devices associated with communication losses in the wireless network over a control channel. After regaining signal coverage, a wireless device monitors the control channel to decode and compare each broadcasted identifier with an identifier of the wireless device. Based on a match between a broadcasted identifier and the identifier of the wireless device, the wireless device transmits a control message which informs the wireless network of the presence of the wireless device. Otherwise, the wireless device normally refrains from transmitting the control message to the wireless network. Advantageously, communication with the wireless network is re-established (if at all necessary) without overburdening the wireless link with unnecessary traffic.
Patent AU-2003206738-B2 (AU)
Title: Pharmaceutical compositions comprising valsartan and NEP inhibitors
Inventor: WEBB RANDY LEE
IPC: A61K45/06
Filed: 2003-01-16
Granted: 2006-12-21
Abstract: The invention relates a pharmaceutical composition comprising a combination of i the AT 1- antagonist valsartan or a pharmaceutically acceptable salt thereof and ii a NEP inhibitor or a pharmaceutically acceptable salt thereof and optionally a pharmaceutically acceptable carrier and to a method for the treatment or prevention of a condition or disease selected from the group consisting of hypertension, heart failure such as acute and chronic congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, diabetic cardiac myopathy, supraventricular and ventricular arrhythmias, atrial fibrillation, atrial flutter, detrimental vascular remodeling, myocardial infarction and its sequelae, atherosclerosis, angina whether unstable or stable, renal insufficiency diabetic and non­-diabetic, heart failure, angina pectoris, diabetes, secondary aldosteronism, primary and secondary pulmonary hypertension, renal failure conditions, such as diabetic nephropathy, glomerulonephritis, scleroderma, glomerular sclerosis, proteinuria of primary renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, peripheral vascular disease, Raynaud's disease, luminal hyperplasia, cognitive dysfunction such as Alzheimer's, glaucoma and stroke, comprising administering a therapeutically effective amount of the pharmaceutical composition to a mammal in need thereof.
Patent AU-2004202689-B2 (AU)
Title: Lift for transporting a load by means of a movable traction means
Inventor: ACH ERNST
IPC: F16H55/50
Filed: 2004-06-18
Granted: 2010-09-09
Abstract: A load transporting apparatus includes a movable traction device connected with the load and having a section in contact with at least one roller in order to guide the traction device. The roller has a coating on a carrier for contact with the traction device section. A coefficient of friction between the traction device and the coating is less than the corresponding coefficient of friction for contact between the traction device and the carrier. The coating reduces or avoids, on movement of the traction device relative to the roller, torsion of the traction device about a longitudinal axis and/or deformation of the traction device transversely to the direction of movement, particularly in the case of movement of the traction device obliquely with respect to the longitudinal direction thereof, and reduces the sensitivity of the traction device to wear, particularly when the traction means is under diagonal tension.