baber/WOPTO huggingface dataset:
Patent EP-4112612-A1 (EP)
Inventor: YOON YOUN JUNG
IPC: C07H1/02
Filed: 2021-02-26
Abstract: The present invention provides an intermediate useful for the synthesis of an SGLT inhibitor and a method for preparing an SGLT inhibitor using same. According to the present invention, by developing a compound of Chemical Formula 5 corresponding to a novel intermediate, the difficulty of purification with existing processes can be solved, the quality requirements for related substances can be matched with only one purification step, and the quality control problem in each step can be solved by performing several steps in situ. The method for synthesizing a compound of Chemical Formula 1 by using a compound of Chemical Formula 5, according to the present invention, enables purification in the step of synthesizing a compound of Chemical Formula 5, thereby solving the problems of existing synthesis processes, in which the quality requirements for related substances was difficult to control step by step due to a continuous process, and minimizing the amount of related substances in a final product. In addition, as the number of purification steps increases, the process can be simplified because purification is not necessarily performed two or more times in one step like in the prior art, thereby maximizing the production yield of a diphenylmethane derivative according to Chemical Formula 1.
Patent EP-4229648-A1 (EP)
Inventor: HARRIS JASON L
IPC: G16H20/17
Filed: 2021-09-15
Abstract: En général, l'invention concerne des systèmes et des procédés pour commander le fonctionnement de dispositifs d'administration de médicament à l'aide d'embases chirurgicales.
Patent EP-4127174-A1 (EP)
Inventor: WILTON STEPHEN
IPC: C12N15/113
Filed: 2021-03-22
Abstract: L'invention concerne un oligomère antisens isolé ou purifié pour modifier l'épissage de pré-ARNm dans l'enzyme de conversion de l'angiotensine 2 (ACE2) pour moduler l'épissage du transcrit de gène ACE2 ou d'une partie de celui-ci qui a une structure de squelette modifiée et des séquences ayant au moins 75 % d'identité de séquence avec de tels oligomères antisens et qui ont une structure de squelette modifiée.
Patent EP-4130055-A1 (EP)
Title: Method for producing petroleum resin for hot-melt adhesive, and method for producing hydrogenated petroleum resin
Inventor: KOBAYASHI MASAHIDE
IPC: C08F8/04
Filed: 2021-03-29
Abstract: Provided is a method for producing a petroleum resin using a tube-type reactor, the method producing a petroleum resin that exhibits good properties as an adhesive component for a hot-melt adhesive which has a narrow molecular weight distribution and a high softening point, and which exhibits good adhesive capability and also has little insoluble matter.A method of producing a petroleum resin by using a raw material containing at least a cyclopentadiene-based component (A) and a styrene-indene-based aromatic component (B) so as to carry out a thermal polymerization reaction of the raw material, the method comprising: a first polymerization reaction step of thermally polymerizing the raw material using a loop reactor; and a second polymerization reaction step of thermally polymerizing a polymerization reaction product obtained in the first polymerization reaction step using a plug flow reactor.
Patent EP-4134647-A1 (EP)
Title: Signal processing circuit and load detection device
Inventor: YAMAMOTO KOSUKE
IPC: G01L1/26
Filed: 2021-03-30
Abstract: A signal processing circuit is a signal processing circuit configured to detect a load on a target, and is configured to obtain a first output value of a first physical sensor that is provided in such a manner that a detection value of the first physical sensor changes in accordance with the load on the target, and a second output value of a second physical sensor that is provided in such a manner that a detection value of the second physical sensor does not change in accordance with the load on the target, the second physical sensor having an electrical characteristic that is the same as an electrical characteristic of the first physical sensor; and the signal processing circuit is configured to calculate, as a load detection value indicating the load on the target, a difference value between the first output value and the second output value.
Patent EP-4229184-A1 (EP)
Inventor: ARAMESH MORTEZA
IPC: C12N5/078
Filed: 2021-10-11
Abstract: The present invention is directed to a method for the cultivation, optionally activation and growth of lymphocytes (T-, B- and NK-cells) by culturing these cells in a suitable cell growth medium on a nanoporous substrate having a pore diameter in the range of about 100 to 500 nm, optionally about 150 to 250 nm.
Patent EP-4208998-A1 (EP)
Inventor: OTENKO OLEKSANDR
IPC: H04L65/40
Filed: 2021-09-01
Abstract: In accordance with an embodiment, described herein is a system and method for providing a reactive flattening map for use with a microservices or other computing environment. In a cloud computing environment, reactive programming can be used with publishers and subscribers, to abstract execution away from the thread of execution while providing rigorous coordination of various state transitions. The described approach provides support for processing streams of data involving one or more publishers and subscribers, by use of a multi-flat-map publisher component, to flatten or otherwise combine events emitted by multiple publishers concurrently, into a single stream of events for use by a downstream subscriber.
Patent EP-4233131-A1 (EP)
Title: Connector for connecting an electrical termination to a printed circuit and corresponding assembly methods
Inventor: BAPTISTE RÉGIS
IPC: H01R4/48
Filed: 2021-10-14
Abstract: The proposed invention relates to a connector (C) for connecting an electrical termination to a printed circuit. The connector takes the form of a metal plate (P) comprising: - a peripheral zone (ZP) for attaching the connector to the printed circuit; - a central opening (OC) for inserting the electrical termination; - a plurality of retaining tabs (PM1, PM2, PM3, PM4) for retaining the electrical termination, each of the retaining tabs extending from the peripheral zone to the central opening, and comprising an elastically deformable portion (PED) via which the retaining tab is connected to the peripheral zone and a free end (EL) forming an edge of the central opening, the free end comprising a rounded portion (AR) and a sharp edge (AV), the rounded portion and the sharp edge being respectively positioned opposite the other such that the rounded portion faces a first surface, referred to as the detachable assembly surface (FAD), of the metal plate, and such that the sharp edge faces a second surface, which is referred to as the permanent assembly surface (FAP), of the metal plate, and which is opposite the first surface.
Patent EP-4237159-A1 (EP)
Inventor: KORTEN MALTE
IPC: B04B5/02
Filed: 2021-09-29
Abstract: The present disclosure provides methods including obtaining an insert comprising a sieve defining openings each having a diameter of 10 to 200 micrometers; placing a volume of a fluid containing a photopolymerizable composition and a contaminant in the insert; and subjecting the volume of the fluid to a centrifugal force to separate the contaminant from at least a portion of the photopolymerizable composition by retaining the contaminant in the insert and passing at least a portion the photopolymerizable composition through the sieve of the insert to provide a separated photopolymerizable composition. Systems are also provided, including an additive manufacturing apparatus, a centrifuge, and an insert configured to be inserted into the centrifuge. The methods and systems can advantageously assist in reclaiming photopolymerizable composition that has been contaminated, for reuse.
Patent EP-4179549-A1 (EP)
Title: Tool for supporting the informed consent of patients ahead of a medical treatment
Inventor: LIPINSKI JENS
IPC: G16H80/00
Filed: 2021-10-18
Abstract: The present invention deals with the technical field of providing information to patients, for example prior to the performance of a medical treatment, and the electronic documentation of the provision of information. The subjects of the present invention are a computer system and a computer program product that make it possible to issue information to a patient in the form of selected information units and to detect and to document the selection and the behaviour of the patient when the information units are issued in order to issue them to a doctor at a later time so that said doctor is able to use this information for a needs-oriented discussion with the patient ahead of the medical treatment.
Patent EP-4217137-A1 (EP)
Inventor: THEZE ALEXIS
IPC: B22F12/50
Filed: 2021-09-24
Abstract: The present document relates to a method for winding a filament (4) for an additive manufacturing device, comprising the steps of: • - providing a filament (4) which is filled with at least 80% metal powder by mass; • - heating the filament (4) up to a temperature of at least 70°C and keeping the filament at this temperature; • - winding the filament (4) about the axis of a coil (110, 142), which is preferably made of metal, the diameter of the coil (110, 142) in the empty state being greater than or equal to a diameter of 100 mm.
Patent EP-4135461-A1 (EP)
Inventor: BAEK SANGKYU
IPC: H04L5/00
Filed: 2021-05-17
Abstract: Provided are a method and device for transmitting and receiving data in a wireless communication system, and an operation method of a terminal in a wireless communication system may include, in case that transmission of a scheduling request (SR) is pending and logical channel-based prioritization is configured for a medium access control (MAC) entity of the terminal, identifying whether a physical uplink control channel (PUCCH) resource associated with transmission of the SR overlaps with a physical uplink shared channel (PUSCH) resource associated with transmission of a message A in a time domain, in case that the PUCCH resource associated with the transmission of the SR does not overlap with the PUSCH resource associated with the transmission of the message A, identifying whether the PUCCH resource associated with the transmission of the SR overlaps with a PUSCH resource associated with uplink data in the time domain, and in case that the PUCCH resource associated with the transmission of the SR overlaps with the PUSCH resource associated with the uplink data, transmitting the SR or the uplink data to a base station by comparing a priority of the PUCCH resource associated with the transmission of the SR with a priority of the PUSCH resource associated with the uplink data.
Patent EP-4243946-A1 (EP)
Inventor: ORTH DOMINIC
IPC: A63B69/20
Filed: 2021-11-09
Abstract: There is provided a training apparatus (20) comprising: a training implement (22) for receiving an impact; a plurality of acceleration sensors (36) arranged inside the training implement (22), each acceleration sensor (36) configured to, in use, measure an acceleration of the training implement (22) in response to an impact against the training implement (22); and a processing circuit programmed to process the measured acceleration by each acceleration sensor (36) so as to compute information about the impact against the training implement (22), wherein the computed information includes an orientation of the impact against the training implement (22).
Patent EP-4252439-A1 (EP)
Title: Management of interference on a v2x channel, by disabling a function on a vehicle
Inventor: LADHARI FADI
IPC: H04W4/48
Filed: 2021-10-21
Abstract: The invention relates to the management of interference related to the use of a single short-range communication channel, referred to as a V2X channel, by a user terminal (UE) and by a land-based motor vehicle (Veh), by disabling a function of the V2X channel on the vehicle.
Patent EP-4248404-A1 (EP)
Inventor: SINHA AYUSHI
IPC: G06T7/55
Filed: 2021-11-16
Abstract: A computer-implemented method of providing a neural network for predicting a three-dimensional shape of an interventional device disposed within a vascular region, includes: training (S140) a neural network (140) to predict, from received X-ray image data (120) and received volumetric image data (110), a three-dimensional shape of the interventional device constrained by the vascular region (150). The training includes constraining the adjusting of parameters of the neural network such that the three- dimensional shape of the interventional device predicted by the neural network (150) fits within the three-dimensional shape of the vascular region represented by the received volumetric image data (110).
Patent EP-4159860-A1 (EP)
Inventor: MATSUKAWA HIROAKI
IPC: C12N1/21
Filed: 2021-06-01
Abstract: Provided are: an anti-IGF-1 receptor humanized antibody which includes CDRs of a light chain and a heavy chain derived from mice parent antibody IGF 11-16, and respective FRs of a light chain and a heavy chain derived from a human antibody, and in which at least one of the CDRs includes at least one amino acid residue substitution with respect to a corresponding CDR of the mice parent antibody; a fragment of the anti-IGF-1 receptor humanized antibody; or a derivative thereof.
Patent EP-4161959-A1 (EP)
Title: Method for determining antibody dissociation rate
Inventor: ZUK ROBERT F
IPC: C07K14/36
Filed: 2021-06-03
Abstract: The present invention is directed to a method of measuring the dissociation rate of the binding of an antibody to an antigen. The method has two phases: a first phase of binding and a second phase of dissociation. The first phase of the assay has a probe coated with an antigen, or protein G, or an anti-human IgG Fc antibody. The probe is immersed in a sample solution containing an antibody, followed by a wash sequence, then the probe is transferred to a reagent with a biotinylated antigen. After an incubation, the antibody bound on the probe binds to the biotinylated antigen to form an immune complex. Fluorescent signal is produced by immersing the probe in a reagent having a fluorescent tagged streptavidin. The last step of the first phase is a measurement of fluorescent on the probe tip. The second phase of the assay is making subsequent fluorescent measurements over time to monitor the loss in fluorescence indicating dissociation of the immune complex and calculating the dissociation rate of the binding of the antibody to the antigen.
Patent EP-4163100-A1 (EP)
Inventor: OBANA TAKAKAZU
IPC: B65D33/38
Filed: 2021-06-07
Abstract: A method of manufacturing a pouch container, includes: a step of forming a pouch bag having one open end, by fusion-bonding a resin layer on an inner side of an end of a first film 11, with a resin layer on an inner side of an end of one or more second films 12 and 13; a step of molding a mouth part member 20 made of a resin, including a brim portion and a standing portion; a step of attaching a lower surface of the brim portion of the mouth part member 20 made of the resin to an outer resin layer of the first film 11 of the pouch bag, by integrating the resins, using one of ultrasonic, heat, or high-frequency welding; a step of filling the pouch bag with contents from the one open end of the pouch bag; and a step of sealing an inside by fusion-bonding the one open end of the pouch bag to seal the pouch bag.
Patent EP-4140522-A1 (EP)
Inventor: CHAOYU HU
IPC: A61M5/32
Filed: 2021-05-13
Abstract: The present invention relates to the technical field of medical instruments, in particular to an automatically-triggered needle protector and an insulin pen needle. The automatically-triggered needle protector at least includes a needle hub, a protective sleeve, a shield, a spring and a support part. The support part at least includes an initial state and a support state and is configured to be switched into the support state from the initial state. In the initial state, a support base body of the support part is in contact with an upper end of the needle hub, and a circumferential limiting mechanism is arranged between the support base body and a needle body installation portion; and in the support state, the support part disengages from sliding grooves, and lower ends of support arms are located above support surfaces. In the above structure, the shield is automatically triggered, a secondary operation is not needed in a protection process, and operation is simple, convenient and fast; and the support part is located on an inner side and supported in a space between the shield and the needle hub in an axial direction, support safety and reliability are better, and meanwhile, a protection state of a needle is not likely to be damaged from outside, thereby effectively preventing secondary usage of the insulin pen needle.
Patent EP-4063237-A1 (EP)
Inventor: YU ZHEN
IPC: B62D5/04
Filed: 2021-06-28
Abstract: The present invention provides vehicle steering control method, apparatus and system. The vehicle steering control method includes that: a vehicle speed signal and a steering angle signal of a steering wheel of a vehicle are acquired; a proportional coefficient of a front wheel steering angle and a rear wheel steering angle of the vehicle is determined according to the vehicle speed signal; the front wheel steering angle is determined according to the steering angle signal; and the rear wheel steering angle is calculated according to the proportional coefficient and the front wheel steering angle, so as to improve the safety and reliability of vehicle steering control.
Patent EP-4173271-A1 (EP)
Title: Cumulative average spectral entropy analysis for tone and speech classification
Inventor: VERGIN RIVAROL
IPC: H04M3/00
Filed: 2021-06-30
Abstract: A contact center system for performing call progress analysis including tone and speech classification according to an embodiment includes at least one processor and at least one memory comprising a plurality of instructions stored thereon that, in response to execution by the at least one processor, causes the contact center system to determine a cumulative average of an entropy of an audio signal received by the contact center system, determine a cumulative average power spectral amplitude and a cumulative average spectral entropy of the audio signal, calculate a difference measure of the audio signal as a difference between the cumulative average of the entropy and the cumulative average spectral entropy, distinguish tones from speech of the audio signal based on the difference measure, and process one or more tones of the audio signal in response to identification of the one or more tones in the audio signal.
Patent EP-4260500-A1 (EP)
Inventor: WU SHUANSHUAN
IPC: H04L1/18
Filed: 2021-12-02
Abstract: Techniques for cross channel occupancy time (COT) hybrid automatic repeat request (HARQ) feedback transmission for sidelink communication in unlicensed spectrum may be performed. In an example, a receiving user equipment (UE) may receive, from a transmitting UE, a first transmission in a first channel occupancy time (COT). The receiving UE may also determine a first feedback occasion is after a last slot of the first COT. The receiving UE may also determine one or more feedback configurations. The receiving UE may also transmit, to the transmitting UE, a feedback message indicating decoding of the first transmission in the first feedback occasion or a second feedback occasion based on the one or more feedback configurations.
Patent EP-4183878-A1 (EP)
Inventor: HONG HAO
IPC: C12N11/084
Filed: 2021-02-18
Abstract: Provided are a PVA membrane immobilized enzyme and a preparation method therefor. The PVA membrane immobilized enzyme comprises a PVA porous membrane and an enzyme entrapped on the PVA porous membrane. The PVA porous membrane is a three-dimensional structured PVA porous membrane. The enzyme is any one selected from transaminase, D-lactate dehydrogenase, cyclohexanone monooxygenase, ketoreductase, alkene reductase, nitrilase, ammonia lyase, amino acid dehydrogenase, imine reductase, alcohol dehydrogenase, ammonium formate dehydrogenase, glucose 1-dehydrogenase and mutants thereof. The three-dimensional structured PVA porous membrane is used as a carrier to immobilize an enzyme in an entrapment manner. The entrapment and immobilization process is simple, conditions are mild, and the specific surface area is large. After entrapping and immobilizing the enzyme in the PVA porous membrane, the enzyme is stable, and cannot be easily leached out in the process of use. The porous structure of the PVA porous membrane used can better transmit reactants and products, is suitable for use in continuous flow biochemical catalysis, and has wide applicability to enzymes.
Patent EP-4166183-A1 (EP)
Title: Humidification tank and ventilation treatment device
Inventor: TIAN XIN
IPC: A61M16/00
Filed: 2021-07-16
Abstract: A humidification tank and a ventilation treatment device. The humidification tank includes a tank body (100) having a cavity, a connector pipe (200) inserted into the cavity, and at least two branch pipes (300) communicated with an outlet end of the connector pipe. The branch pipes can provide airflow towards different directions so that gas reaches more positions in the cavity, the existence of a position to which the gas cannot be blown in the cavity is avoided, the occurrence of a dead zone of airflow is avoided. The fluidity of gas inside the cavity is improved, and a gas flowing path is lengthened, thus improving the humidifying effect of gas.
Patent EP-4255852-A1 (EP)
Inventor: BURSZTEIN MACIEJ
IPC: C02F1/00
Filed: 2021-12-06
Abstract: A water- treatment device (100) comprising a head (2) and a water-treatment cartridge (1) configured for being arranged in the head (20) of the water-treatment device (100), which the device (100) is configured for treating water in the water-treatment cartridge (1). The water-treatment device (100) is characterized in that the device (100) comprises a first element (9A, 9B) of the orienting-ejecting means, arranged on the water-treatment cartridge (1), and a second element (26A, 26B) of the orienting-ejecting means, arranged on the head (20) of the water-treatment device (100), wherein, when the first element (9A, 9B) and the second element (26A, 26B) of the orienting-ejecting means are engaged, the position of the water-treatment cartridge (1) in the head (20) of the water-treatment device (100) is stabilized, when the cartridge (1) is mounted in the head (20) of the device (100), and there is provided ejection of the water-treatment cartridge (1) from the head (20) of the water-treatment device (100) during removal of the cartridge (1) from the device (100) by rotating said cartridge (1) around its longitudinal axis relative to the head (20) of the water- treatment device (100).
Patent EP-4180915-A1 (EP)
Inventor: LIU ZAO
IPC: G06F1/26
Filed: 2021-05-15
Abstract: A server power supply circuit and a server are provided. In this application, the power supply circuit includes a first voltage input line, a second voltage input line, a ground cable, a switch module, and a voltage limiting module. One end of the first voltage input line and one end of the second voltage input line are separately configured to connect to a power supply. The switch module and the voltage limiting module are connected in series and located between the first voltage input line and the ground cable. When a voltage of the first voltage input line is greater than a conduction voltage, both the switch module and the voltage limiting module are in an on state, so that the server can be protected from a relatively high voltage. When the voltage of the first voltage input line decreases and is less than the conduction voltage after the voltage of the first voltage input line is greater than the conduction voltage, the voltage limiting module is in an off state. In this way, the power supply circuit can work normally and supply power to the server, so that the server is applicable to different power supply scenarios without switching a power supply module.