baber/WOPTO huggingface dataset:
Patent CA-2971929-A1 (CA)
Inventor: SZETO HAZEL H
IPC: A61P39/06
Filed: 2005-01-21
Abstract: Linvention présente une méthode de réduction de dommage par oxydation chez un mammifère, un organe enlevé ou une cellule en ayant besoin. La méthode comprend ladministration dune quantité efficace dun peptide aromatique cationique. La méthode comprend la mise en contact de la cellule avec une quantité efficace de peptide aromatique cationique comportant au moins une charge positive nette; un minimum de quatre acides aminés; un maximum denviron vingt acides aminés; une relation entre le nombre minimum de charges nettes positives (pm) et le nombre total de résidus dacide aminé (r) où 3p m est le plus grand nombre qui est inférieur ou égal à r+1; et une relation entre le nombre minimum de groupes aromatiques (a) et le nombre total de charges positives nettes (pt) où 2a est le plus grand nombre qui est inférieur ou égal à p t +1, sauf lorsque a est 1, p t peut également être 1.
Patent CA-2972087-A1 (CA)
Title: Vehicule de travaux ferroviaires, train de travaux comprenant un tel vehicule de travaux et procede de fabrication d'une voie ferroviaire
Inventor: COLLIGNON FABRICE
IPC: E01B35/00
Filed: 2017-06-28
Abstract: Ce véhicule (3) de travaux ferroviaires, comprend un portique (21), qui inclut des montants, et un premier moyen de déplacement du véhicule de travaux ferroviaires par rapport au sol selon au moins une direction d'avance (D1) du véhicule de travaux ferroviaires. Selon l'invention, le véhicule de travaux ferroviaires (3) comprend au moins un bras robotisé (19) monté sur le portique (21), entre les montants, ce bras robotisé étant configuré pour disposer au moins un insert (33) dans une dalle (11) de béton frais situé dans une zone de travail (31) située au-dessous du portique, le portique (21) comprenant un support de toit (27) qui relie entre eux les montants par une extrémité supérieure de ces derniers. Le bras robotisé (19) est suspendu au support de toit.
Patent CA-2975301-A1 (CA)
Title: Hydrogel particles with tunable optical properties and methods for using the same
Inventor: KIM JEFFREY
IPC: G01N33/22
Filed: 2016-02-08
Abstract: Hydrogel particles and their use in cytometic applications are described. The hydrogel particles described herein are selectively tunable to have at least one optical property substantially similar to the at least one optical property of a target cell. In this regard, the hydrogel particles provided herein in one aspect, are used as a calibration reagent for the detection of a target cell in a sample.
Patent CA-2976075-A1 (CA)
Inventor: STANEK LISA M
IPC: C12N15/113
Filed: 2016-02-09
Abstract: Provided herein are RNAi molecules including a first strand containing a guide sequence and a second strand comprising a non-guide sequence where the non-guide sequence contains a bulge opposite the seed region of the guide sequences; e.g., opposite the cleavage sequence. In some aspects, the invention provides RNAi for treating Huntington's disease. Further provided herein are expression cassettes, vectors (e.g., rAAV, recombinant adenoviral, recombinant lentiviral, and recombinant HSV vectors), cells, viral particles, and pharmaceutical compositions containing the RNAi. Yet further provided herein are methods and kits related to the use of the RNAi, for example, to treat Huntington' s disease.
Patent CA-2976450-A1 (CA)
Inventor: ZAWADZKI MICHAEL ANDREW
IPC: A47K10/16
Filed: 2015-02-27
Abstract: The disclosure provides tissue webs and products comprising cross-linked cellulosic fibers. In certain embodiments cross-linked cellulosic fibers are selectively disposed in one or more layers of a multi-layered tissue, wherein the tissue layer comprising cross-linked fibers is adjacent to a layer which is substantially free from cross-linked fiber. The cross-linked fibers may include hardwood kraft fibers reacted with a cross-linking agent selected from the group consisting of DMDHU, DMDHEU, DMU, DHEU, DMEU, and DMeDHEU. Tissue products and webs produced in this manner generally have improved sheet bulk, without losses in strength, compared to similar tissue products produced without cross-linked cellulosic fibers. As such the tissue products of the present invention generally have a basis weight from about 10 to about 50 gsm, a sheet bulk greater from about 8.0 to about 12.0 cc/g and geometric mean tensile from about 730 to about 1,500 g/3".
Patent CA-2977053-A1 (CA)
Inventor: SCHMID KEVIN G
IPC: A61M5/172
Filed: 2016-02-18
Abstract: A medical device comprising an infusion device comprising a fluid reservoir to contain a therapeutic fluid and a transcutaneous access tool fluidly coupled to the fluid reservoir, the transcutaneous access tool configured to deliver the therapeutic fluid subcutaneously to a patient; wherein the infusion device operates in a stand-by mode prior to the therapeutic fluid being introduced into the fluid reservoir; wherein the infusion device operates to deploy the transcutaneous access tool within a predetermined deployment time period upon filling the fluid reservoir to a predetermined fill level with the therapeutic fluid.
Patent CA-2977641-A1 (CA)
Inventor: JOHNSON ASHLEY BERNARD
IPC: E21B29/00
Filed: 2016-02-18
Abstract: Tubing in a borehole is removed using a rotary milling tool comprising a plurality of elements projecting from or extensible from the body of the tool. The elements are distributed azimuthally around the tool body. The elements comprise cutters to remove material from the tubing and outward facing guide surfaces for sliding contact with an inner surface of the tubing. As the tool is rotated and advanced, forward cutters contact the inner surface removing material from the tubing and exposing a renewed interior tubing surface with a diameter swept out by the cutter. The outward facing guide surfaces extend the same distance from the tool body as the forward cutters producing a sliding contact with the newly created inward facing surface. Further cutters, disposed behind the outward facing guide surfaces, with respect to motion of the tool through the tubing, remove the remaining portion of the tubing.
Patent CA-2983506-A1 (CA)
Inventor: D'JOOS JIMMY
IPC: E04H3/12
Filed: 2017-10-23
Abstract: The apparatus is for use with a facility of the type having: a generally horizontal, planar, base surface; and a generally horizontal, planar raised floor surface, elevated in relation to the base surface such that a step is formed between the base surface and raised surface. The apparatus comprises an arrangement of struts carrying wheels adapted such that as the apparatus is rolled from the base surface to the raised surface the struts are unlocked for movement towards a retracted position; during movement of the apparatus from the base surface to the raised surface, the struts are urged from the extended position to the retracted position; and as the apparatus is driven from the raised surface to the base surface, the struts are urged to the extended positions.
Patent CA-2984222-A1 (CA)
Inventor: MACKNIK STEPHEN L
IPC: A61B5/11
Filed: 2015-04-27
Abstract: Systems and methods for detecting onset, presence, and progression of particular states, including intoxication, include observing eye movements of a subject and correlating the observed movements to known baseline neurophysiological indicators of intoxication. A detection system may record eye movement data from a user, compare the eye movement data to a data model comprising threshold eye movement data samples, and from the comparison make a determination whether or not intoxication or impairment is present. The detection system may alert the user to take corrective action if onset or presence of a dangerous condition is detected. The eye movements detected include saccadic and intersaccadic parameters such as intersaccadic drift velocity. Measurements may be collected in situ with a field testing device. An interactive application may be provided on a user device to provoke the desired eye movements during recording.
Patent CA-2988508-A1 (CA)
Inventor: METZ BENJAMIN
IPC: F17D1/02
Filed: 2016-06-08
Abstract: The device (10, 20, 30) for injecting dihydrogen into a flow of natural gas originating from a first natural gas distribution network (105) comprises: a gas pipe (110) for connecting to the first distribution network through which a flow of natural gas passes, a pipe (115) for feeding dihydrogen, comprising a reservoir (120) for intermediate storage of dihydrogen, a sensor (125) for sensing the flow rate of the flow of natural gas passing through the connecting pipe, said sensor providing a signal representative of the flow rate measured, a means (130) for regulated injection of the dihydrogen stored in the reservoir for intermediate storage into the gas passing through the connecting pipe, depending on the flow rate measured, a sensor (185) for sensing at least one characteristic of a composition of the gas mixture, and a means (135) for feeding the mixture of natural gas and dihydrogen, injected at a second natural gas distribution network (140), depending on each characteristic of the sensed composition of the mixture.
Patent CA-2989383-A1 (CA)
Title: Procede de conception assistee par ordinateur de proteines
Inventor: FLEISHMAN SAREL
IPC: C12N15/00
Filed: 2015-07-06
Abstract: L'invention concerne un procédé de construction d'une bibliothèque de séquences d'acides aminés présentant un repli structural commun, et un procédé de conception et de sélection d'une séquence d'acides aminés, ayant une affinité désirée avec une surface moléculaire d'intérêt d'une entité moléculaire, utilisant la bibliothèque. Les procédés sont basés sur un échantillonnage stochastique de conformations de squelettes et de motifs de conservation des acides aminés observés dans des structures protéiques disponibles au niveau expérimental présentant le repli structural commun.
Patent CA-2989720-A1 (CA)
Title: High-strength steel with high minimum yield strength and method of producing such a steel
Inventor: BRUNS HEINZ-WERNER
IPC: C22C38/46
Filed: 2015-07-24
Abstract: Disclosed is a high-strength steel having a minimum yield strength of 1300 MPa may include 0.23% to 0.25% by weight carbon, 0.15% to 0.35% by weight silicon, 0.85% to 1.00% by weight manganese, 0.07% to 0.10% by weight aluminium, 0.65% to 0.75% by weight chromium, 0.02% to 0.03% by weight niobium, 0.55% to 0.65% by weight molybdenum, 0.035% to 0.05% by weight vanadium, 1.10% to 1.30% by weight nickel, 0.0020% to 0,0035% by weight boron, and 0.0007% to 0.0030% by weight calcium. The high-strength steel may also include iron, unavoidable impurities, and other minor components, A method for producing such high-strength steel is also disclosed.
Patent CA-2990415-A1 (CA)
Inventor: MITCHEL WADE
IPC: A01B59/06
Filed: 2016-06-22
Abstract: A shifting module for releasable securement on the lower two arms of a conventional three- point hitch of a tractor and for laterally shifting a pull-type implement mounted on the shifting module. The shifting module includes a lateral support having a pin on either end section for grasping and securement by the lower two arms of the three-point hitch. A traveler is mounted on the lateral support and a linear actuator operates to shift the traveler along the lateral support to any desired position along the lateral support. A hitch on the traveler is used for mounting of the pull- type implement so that the implement can be reliably and accurately positioned along a desired path.
Patent CA-2990450-A1 (CA)
Inventor: JIANG WEI-DONG
IPC: A61K39/395
Filed: 2016-06-29
Abstract: Provided are anti-vascular endothelial growth factor receptor 2 (VEGFR2) antibodies, and antigen binding fragments thereof. Also provided are isolated nucleic acid molecules that encode the anti-VEGFR2 antibodies or antigen binding fragments thereof, related expression vectors, and host cells. Provided are methods of making anti-VEGFR2 antibodies and antigen binding fragments thereof. Also provided are related pharmaceutical compositions comprising anti-VEGFR2 antibodies (or antigen binding fragments thereof) and methods of their use in the treatment of pathological conditions characterized by excessive angiogenesis.
Patent CA-2990639-A1 (CA)
Inventor: PRETZ MATTHEW T
IPC: B01J19/32
Filed: 2016-06-25
Abstract: A fluid solids contacting device comprising a vessel; a first grid assembly section which comprises a plurality of horizontal chords spaced horizontally apart from each other and a plurality of grid platforms inserted between the horizontal chords; wherein each horizontal chord comprises a structural member with sufficient mechanical strength to withstand fluidized forces in the vessel; a plurality of chairs attached to an inside surface of the vessel and spaced circumferentially apart to support the structural member; and wherein each structural member is supported on one or more of the plurality of chairs is provided.
Patent CA-2991706-A1 (CA)
Title: Radio resistant au brouillage
Inventor: HINES ANDREW T
IPC: H04B1/403
Filed: 2016-07-08
Abstract: L'invention concerne un appareil, un système et un procédé pour une communication sans fil avec des dispositifs à distance qui réduisent ou éliminent le brouillage provenant d'un bruit à valeur moyenne nulle et de signaux déterministes dans la bande de fréquences de système d'exploitation. Un dispositif d'interrogation utilise la juxtaposition du temps d'initiation de signaux émis séquentiels ou d'ensembles de signaux émis avec l'accumulation synchrone des signaux reçus résultants pour réduire la puissance relative de signaux de brouillage tout en augmentant la puissance relative du signal souhaité. L'appareil, le système et le procédé sont particulièrement avantageux lorsque ces derniers sont utilisés pour extraire des données d'identification et/ou de capteur à partir de capteurs sans fil passifs et d'étiquettes.
Patent CA-2991892-A1 (CA)
Title: Dispositifs electrochromiques sans danger pour les oiseaux
Inventor: MATHEW JOHN GORDON HALBERT
IPC: G02F1/153
Filed: 2016-07-07
Abstract: Divers modes de réalisation de la présente invention se rapportent à des fenêtres électrochromiques qui sont sans danger pour les oiseaux, ainsi que des procédés et un appareil permettant de former de telles fenêtres. Les fenêtres sans danger pour les oiseaux comprennent un ou plusieurs éléments qui rendent la fenêtre visible pour les oiseaux de sorte que les oiseaux se rendent compte qu'ils ne peuvent pas voler à travers la fenêtre. Les fenêtres sans danger pour les oiseaux peuvent être utilisées pour réduire au minimum les collisions entre les fenêtres et les oiseaux et, par conséquent, réduire au minimum les morts aviaires résultant de ces collisions. Dans divers modes de réalisation, une fenêtre peut être conçue de sorte que le motif soit visible par les oiseaux. Dans ces cas ou d'autres, la fenêtre peut être rendue voilée, le voile étant visible par les oiseaux. Le motif et/ou le voile peuvent être visibles à des longueurs d'onde qui correspondent aux rayons UV, et faiblement perceptibles (le cas échéant) dans des longueurs d'onde dans le spectre visible par les humains.
Patent CA-2995523-A1 (CA)
Inventor: CLARK RICHARD HUGH
IPC: C10L1/02
Filed: 2016-08-12
Abstract: Diesel fuel composition suitable for use in an internal combustion engine comprising: (a) 2 mass% to 30 mass% of kerosene having a kinematic viscosity at 40°C of 1.5 mm2/s or less and a density of 810 kg/m3 or less; (b) 2 mass% to 20 mass% of Fischer-Tropsch derived base oil having a kinematic viscosity at 40°C of 7.5 mm2/s or greater and a density of 790 kg/m3 or greater; and (c) diesel base fuel. The diesel fuel composition of the present invention provides improved cold flow properties while simultaneously maintaining other properties such as viscosity and density within diesel fuel specification requirements.
Patent CA-2996009-A1 (CA)
Inventor: WEI XIAOLIN
IPC: G06T17/05
Filed: 2016-09-23
Abstract: A method for forming a reconstructed 3D mesh includes receiving a set of captured depth maps associated with a scene, performing an initial camera pose alignment associated with the set of captured depth maps, and overlaying the set of captured depth maps in a reference frame. The method also includes detecting one or more shapes in the overlaid set of captured depth maps and updating the initial camera pose alignment to provide a shape-aware camera pose alignment. The method further includes performing shape-aware volumetric fusion and forming the reconstructed 3D mesh associated with the scene.
Patent CA-2996019-A1 (CA)
Inventor: VAN MEULDER GUIDO
IPC: C09D5/00
Filed: 2016-09-09
Abstract: The present invention relates to radiation curable coating composition (I) consisting essentially of: - from 20 to 95 wt% of one or more (meth)acrylated compounds (a), - from 5 to 80 wt% of one or more metal salts of a C10 to C22 fatty acid (b), and - optionally, from 0 to 10 wt% of one or more additives (c), wherein the wt% of compounds (a) to (c) add up to at least 95%, preferably add up to 100%. Compositions of the invention are compatible with a whole range of radiation curable materials and with the standard additives like the standard matting agents. Compositions of the invention permit to obtain a dead matt effect using lower amounts of matting agents like silica and/or waxes. Dead matt effects can be obtained over a wide range of coating thicknesses.
Patent CA-2997151-A1 (CA)
Title: Folding x-frame chair with extended backrest
Inventor: COHEN WARREN
IPC: A47C4/28
Filed: 2018-03-02
Abstract: A folding chair assembly having a seat framework and a backrest framework arranged in an X-frame arrangement. The backrest framework is joined to the seat framework at pivot joints. The seat framework and the backrest framework can move about the pivot joints between an open configuration and a folded configuration. Frame extensions are provided that are joined to the backrest frame with hinge joints. The hinge joints enable the frame extensions to be folded about the hinge joints between a first position, where said frame extensions abut against the backrest framework, and a second position, where the frame extensions extend away from the backrest framework and increase its effective length.
Patent CA-2997667-A1 (CA)
Title: Composants d'alliage 7xxx trouvant une application dans la defense et presentant une resistance aux eclats amelioree
Inventor: FRANKLIN JACK
IPC: F41H5/00
Filed: 2016-09-07
Abstract: La présente invention concerne des composants de blindage constitués d'un aluminium haute résistance, tel que les alliages d'aluminium de la série 7xxx, pouvant être utilisés dans des systèmes de protection balistique civils ou militaires. Elle concerne plus particulièrement des composants de blindage tels que des parois d'enveloppe blindées et des éléments blindés d'appoint dans des véhicules.
Patent CA-2997936-A1 (CA)
Inventor: Tan yuandong
IPC: A61B17/128
Filed: 2015-10-10
Abstract: A reposable endoscopic surgical clip applier includes a handle assembly (100) configured to releasably engage at least two different endoscopic assemblies (200,300,400). The handle assembly (100) is configured such that a ratcheting function thereof is disabled upon engagement of an endoscopic assembly (300) therewith that is not intended for ratcheting use and such that the ratcheting function is enabled upon engagement of an endoscopic assembly (400) therewith that is intended for ratcheting use. Endoscopic assemblies (200,300,400) for use with the handle assembly (100) are also provided.
Patent CA-2999873-A1 (CA)
Inventor: VERMA AJAY
IPC: A61B6/00
Filed: 2016-09-23
Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.
Patent CA-2999967-A1 (CA)
Title: Agrochemical composition
Inventor: IIGAYA Masayuki
IPC: A01N47/40
Filed: 2016-09-28
Abstract: A composition comprising: (A) an aqueous agrochemically active compound such as acetamiprid; (B) a polyhydric alcohol; (C) a sodium alkylnaphthalenesulfonate/formalin condensate or a modified styrene/maleic anhydride copolymer; (D) a thickener such as xanthan gum; (E) inorganic particles formed of at least one material selected from the group consisting of silica, montmorillonite and attapulgite; and (F) water.
Patent CA-3001201-A1 (CA)
Inventor: CEYLAN ISMAIL
IPC: A61K31/5375
Filed: 2016-10-14
Abstract: Combination comprising an aminothiolester compound or a pharmaceutically acceptable salt thereof and a compound able to increase the H 2 0 2 level in cancer cells of a subject, for use as a medicament The present invention relates to a combination comprising an aminothiolester compound or a pharmaceutically acceptable salt thereof, in particular the S-methyl 4-(dimethylamino)-4-methylpent-2-ynethioate or a pharmaceutically acceptable salt thereof, and more particularly the 4-(Dimethylamino)-4-methyl-2-pentynethioic acid S-methyl ester fumarate, and a compound able to increase H 2 0 2 level in cancer cells of a subject, in particular for use for the treatment of cancer in a subject, wherein cancer cells of said subject do not overproduce H 2 0 2 in comparison to a control value and have a level of GSH below 5 nmol for 25000 cells.
Patent CA-3003046-A1 (CA)
Title: Calibrating sensor unit orientation for use in a vehicle monitoring system
Inventor: SLJIVAR SLAVEN
IPC: G01P21/00
Filed: 2018-04-30
Abstract: This disclosure relates to a system and method for calibrating sensors upon installation in a vehicle. The system includes a sensor set configured to generate output signals conveying vectors of acceleration of the vehicle. The system determines a three-dimensional orientation of the sensor set in relation to the vehicle. The system converts output signals from the sensor set into vectors of acceleration of the vehicle.
Patent CA-3006240-A1 (CA)
Title: A stepwise refinement detection method for pavement cracks
Inventor: LI QINGQUAN
IPC: G06T7/00
Filed: 2015-04-27
Abstract: Disclosed is a stepwise-refinement pavement crack detection method. A processing on a pavement image comprises the following main steps: a road mark extraction and processing, an ROA extraction, an ROA-based adaptive segmentation by thresholds, an ROC extraction and an ROC directional feature weighting-based region growth. On the basis that a crack is a collection of pixel points having similar gray scales and has a significant spatial aggregation feature, the present invention can quickly extract an ROA, quickly position, via the ROA, a possible gray-scale section and a spatial position of a crack, adaptively segment an image by thresholds, establish a confidence evaluation criteria, and accurately extract an ROC. A crack growing direction estimation method based on segmental weighting can accurately estimate a growing trend of a crack. The present invention employs an improved region growth method, and a crack utilizes a confidence region as a seed region and grows with the growing trend of the seed region, thus fully ensuring an accuracy of crack growth and a completeness of crack detection.
Patent CA-3009123-A1 (CA)
Title: Plasmid constructs for heterologous protein expression and methods of use
Inventor: CAMPBELL JEAN
IPC: C12N15/85
Filed: 2016-12-16
Abstract: Provided are plasmid vector constructs encoding multiple immunomodulatory proteins where each protein or component thereof can be expressed utilizing appropriate promotors and/or translation modifiers. Additional immunomodulatory proteins and genetic adjuvants containing shared tumor antigens can be added to further therapeutic potential as well as allow tracking of therapeutic treatment. Also provides are methods of expressing the plasmid constructs.