baber/WOPTO huggingface dataset:
Patent MX-2020011355-A (MX)
Title: Method for producing human alloe-specific regulatory t cells on a large-scale stable in the presence of pro-inflammatory cytokines with therapeutic potential in transplantation.
Inventor: ALBERÚ GÓMEZ JOSEFINA
IPC: C12N5/078
Filed: 2020-10-26
Abstract: The present invention discloses a methodology to obtain large numbers of in vitro differentiated human Tr1 cells specific for the donor antigen(s) with stable suppressor phenotype and function in the presence of proinflammatory cytokines by co-culture of tolerogenic dendritic cells ( DC10) derived from donor monocytes with naïve T cells from a genetically unrelated (allogeneic) recipient. The cells obtained express a Tr1 regulatory phenotype (CD4+, CD49b+, LAG-3+), producers of IL-10, enriched in the co-inhibitory receptors PD1, TIM-3, CD39, CTLA-4, and TIGIT. Also, it has an allospecific suppressor function towards the donor antigens. Said cells maintain their stable phenotype and function in the presence of proinflammatory cytokines IL-1ß, IL-6, IFN-?, and TNF-?. The number, purity, and stability of the Tr1 generated to make them candidates for use as therapeutic tools in transplantation.
Patent MX-2021001386-A (MX)
Title: Engagement and disengagement with external gear box style pumps.
Inventor: MORRIS JEFFREY G
IPC: F04B19/04
Filed: 2019-07-29
Abstract: A system and a method for producing fracturing fluid, comprising: engaging an engagement coupling attached to one end of a gear box dual shaft to a gear box connector of an external gear box, wherein the external gear box is part of a pump; rotating the gear box dual shaft to drive the pump after engaging the engagement coupling with the gear box connector; disengaging the engagement coupling from the gear box connector; and rotating the gear box dual shaft without driving the pump after disengaging the engagement coupling with the gear box connector.
Patent MX-2021001849-A (MX)
Title: Robotic effector to hold, handle, and transport canvas or textile garments.
Inventor: MARTINEZ FIERROS ALEJANDRO
IPC: B41F15/08
Filed: 2021-02-15
Abstract: The present invention relates to an apparatus for unloading and transporting a garment stamped by a screen printing process from an adhesive plate. It characterizes by comprising (a) a collision mechanism 200 coupled to a robot with (i) a motor 208 coupled to a gearbox 202 transmitting torque to a shaft, (ii) a drive link 207, (iii) a collision link 205, pivotally coupled to drive link 207 and a pivot 210. Also, it includes (b) a garment clamping mechanism 300 attached to the collet mechanism 200 comprising first and second clamp parts 305, 306, actuated by pistons 301.
Patent MX-2021002767-A (MX)
Title: Three-dimensional scanner with data collection feedback.
Inventor: SHARAPOV ALEXANDER ALEXANDROVICH
IPC: G01B5/00
Filed: 2019-08-29
Abstract: A three-dimensional (3D) scanner, which is in communication with a display, includes one or more optical sensors. The scanner scans, using the one or more optical sensors, an object having a surface. The scanning generates data corresponding to a 3D shape of at least a portion of the surface of the object. The scanner generates a 3D reconstruction of the shape of the surface of the object. The scanner provides a preview of the 3D reconstruction of the at least portion of the shape of the surface of the object. The scanner provides, to the display, for rendering with the preview of the 3D reconstruction of the at least portion of the shape of the surface of the object, an indication of at least one of a quantity or a quality of the data corresponding to the 3D shape of the at least portion of the surface of the object.
Patent MX-2021004184-A (MX)
Title: Compositions containing thermally conductive fillers.
Inventor: NAKAJIMA MASAYUKI
IPC: C08K3/36
Filed: 2019-10-14
Abstract: Disclosed is a composition comprising an electrophile, a nucleophile, and a thermally conductive filler package. The filler package may comprise thermally conductive, electrically insulative filler particles that may have a thermal conductivity of at least 5 W/m.K (measured according to ASTM D7984) and a volume resistivity of at least 10 Î©m (measured according to ASTM D257, C611, or B193) and that may be present in an amount of at least 90 % by volume based on total volume of the filler package. The thermally conductive filler package may be present in an amount of at least 10 % by volume percent based on total volume of the composition. The present invention also is directed to a method for treating a substrate and to substrates comprising a layer formed from a compositions disclosed herein.
Patent MX-2021004423-A (MX)
Title: Instant mortar.
Inventor: VALDES LOZANO FERNANDO MARTÍN
IPC: C04B7/02
Filed: 2021-04-16
Abstract: The present invention relates to a formulation containing Portland cement, carbonates, zeolites, barites, fluorites, and silicates, with at least 40% of the particles having a grain size of less than 0.841 mm. The mineralized components contribute between 60% and 80% of the total weight of the mortar formulation. Also, Portland cement contributes between 14% and 24% of the total weight of the mortar formulation. Additionally, it provides a lightweight 200 mesh formulation containing Portland cement and 0.400mm mineralized particle calcium, with at least 60% of the mineralized calcium particles having a grain size of less than 0.074 mm. The mineralized components contribute between 60% and 80% of the total weight of the mortar formulation, contributing between 14% and 24% of the total weight.
Patent MX-2021004430-A (MX)
Title: Process for producing ammonium (meth-) acrylate.
Inventor: ZIMMERMANN TOBIAS JOACHIM
IPC: C12P7/40
Filed: 2019-10-17
Abstract: The present invention relates to a process for preparing ammonium (meth-) acrylate, aqueous ammonium (meth-) acrylate solutions obtainable by such process, and (meth-) acrylic acid homopolymers or copolymers obtainable by polymerizing such ammonium (meth-) acrylate. The invention furthermore relates to a modular, relocatable bioconversion unit for manufacturing aqueous ammonium (meth-) acrylate solutions.
Patent MX-2021004466-A (MX)
Title: Optical articles comprising encapsulated microlenses and methods of making the same.
Inventor: MARCHAL JEANNE
IPC: B29D11/00
Filed: 2019-09-27
Abstract: The present disclosure includes optical articles comprising a lens having first and second lens surfaces and a protective layer having first and second protective surfaces that is coupled to the lens such that the first protective surface is disposed on the second lens surface. The optical article can comprise a plurality of convex or concave optical elements defined on the second lens surface or the first protective surface. The protective layer can have a maximum thickness larger than a maximum height of each of the optical elements such that the protective layer encapsulates the optical elements.
Patent MX-2021006887-A (MX)
Title: Trash receptacle with snap lid closure.
Inventor: FITZGERALD THOMAS M
IPC: B65D43/16
Filed: 2021-06-10
Abstract: The invention relates to a lid mechanism, such as those for trash containers and more particularly to a lid mechanism which is operable with only one hand.
Patent MX-2021008768-A (MX)
Title: Method for production of 4-cyano benzoic acid or salts thereof.
Inventor: KORADIN CHRISTOPHER
IPC: C12P13/00
Filed: 2020-01-20
Abstract: The invention is directed to methods for the production of 4-cyano benzoic acid or salts thereof from terephthalonitrile using nitrilase as catalyst and compositions comprising 4-cyano benzoic acid.
Patent MX-2021008880-A (MX)
Title: Dual functional spun + filament fiber woven terry cooling towel.
Inventor: LAWRENCE DAVID CHAD
IPC: D02G3/38
Filed: 2020-01-22
Abstract: Embodiments of the invention provide for terry fabric including a first side configured to exhibit absorbency capabilities and a second side configured to exhibit cooling capabilities. The first side can include a spun fiber loop including a plurality of pile warp yarn, and the second side can include a plurality of weft yarn and a plurality of ground warp yarn, wherein at least one of the plurality of weft yarn and the plurality of ground warp yarn includes synthetic filament yarn.
Patent MX-2021012921-A (MX)
Title: Liquid pressure reducing valve.
Inventor: TAYLOR DAVID BRIAN
IPC: G05D16/20
Filed: 2021-05-06
Abstract: A spring loaded pressure reducing valve (1) has an inlet connected to a pressurized water main (6). An outlet (7) from the chamber connects to a network (8) of pipes for local distribution of water. A compression spring (21) acts at its lower end (22) on the top of a diaphragm (19). The upper end (23) of the spring abuts a spring drive member (24) at the end of a drive tube (25) of a servo device (26). The spring drive member can be advanced by a motor to further compress the spring or retracted to relieve compression. Downstream from the outlet (7), the pipework 8 of the local distribution network extends. In it adjacent the outlet is a flow meter (32) and a pressure sensor (33). These are electronically connected to a controller (34). The pressure at the regulator is set based on the measured flow.
Patent MX-2021012966-A (MX)
Title: Engineered cas9 with broadened dna targeting range.
Inventor: CONG LE
IPC: A61K48/00
Filed: 2020-04-24
Abstract: The disclosure provides variant Staphylococcus aureus Cas9 (SaCas9) proteins with altered specificity for protospacer adjacent motif (PAM) sequences. The disclosure also is directed to CRISPR/Cas9 systems and methods of altering a genomic DNA sequence using the variant SaCas9 protein. Methods of generating variant Cas9 proteins with altered PAM specificity are also disclosed.
Patent MX-2021013100-A (MX)
Title: Printing systems and methods including multilayer films.
Inventor: MORRIS BARRY ALAN
IPC: G03G9/12
Filed: 2020-04-27
Abstract: Embodiments of the present disclosure are directed to printing systems and methods that may include an ink composition including electrically charged ink particles dispersed in a hydrocarbon liquid and a multilayer film. The multilayer film may include a polymeric core layer; and one or more printing layers adjacent to the polymeric core layer. The one or more printing layers may include at least 50 wt.% of an ethylene vinyl acetate copolymer having acid and acrylate functional groups. The ethylene vinyl acetate copolymer having acid and acrylate functional groups may include from 0.5 wt.% to 4 wt.% methacrylic or acrylic acid; from 0.5 wt.% to 4 wt.% acrylate, from 7 wt.% to 40 wt.% vinyl acetate; and the balance ethylene, based on the total weight of the ethylene vinyl acetate copolymer having acid and acrylate functional groups.
Patent MX-2022000274-A (MX)
Title: Acrylic polymer and adhesive compositions.
Inventor: PALLIARDI MARY
IPC: C08F220/10
Filed: 2020-05-06
Abstract: Acrylic polymers and pressure sensitive adhesive compositions prepared from (i) from about 1 to about 10 wt% of a carboxy functional monomer component, (ii) from about 50 to about 90 wt% of a low Tg alkyl acrylate monomer component, (iii) from about 1 to about 20 wt% of a tertiary amine functionalized alkyl acrylate monomer component, and (iv) optionally, up to 50 wt% of a vinyl ester monomer component are disclosed. The acrylic polymers and pressure sensitive adhesives are ideally suited for skin contact applications, particularly as diagnostic patches, transdermal drug-delivery patches, and dermal patches for delivery of skin actives.
Patent MX-2022003446-A (MX)
Title: Lipid vesicle compositions with penetration enhancing agents.
Inventor: FOLDVARI MARIANNA
IPC: A61K9/127
Filed: 2020-09-23
Abstract: The present application is related to a pharmaceutical composition a biphasic lipid vesicle comprising a lipid bilayer comprising vesicle forming lipids; an oil-in-water emulsion stabilized by one or more surfactants; one or more compounds; and one or more penetration enhancing agents. The one or more penetration enhancing agents include one or more non-ionic surfactants having a hydrophilic-lipophilic balance (HLB) of about 10 or less, alone or combination with one or more penetration enhancing agents selected from one or more of terpenes, alkaloids, salicylate derivatives, and polycationic surfactants and combinations thereof. The present application is also related to a pharmaceutical composition comprising a biphasic lipid vesicle comprising a lipid bilayer comprising vesicle forming lipids; an oil-in-water emulsion stabilized by one or more polycationic surfactants; and one or more compounds.
Patent MX-2022004596-A (MX)
Title: Hemodialysis systems, cassettes and methods.
Inventor: GRANT KEVIN L
IPC: A61M1/14
Filed: 2011-02-25
Abstract: Hemodialysis dialysis systems comprising a dialysis unit and user interface unit adapted to display safety critical information related to a dialysis process are disclosed. Hemodialysis systems of the invention may include a dialysate flow path including a balancing circuit, a mixing circuit, and/or a directing circuit. The circuits may be defined within one or more cassettes. The fluid circuits may be at least partially isolated, spatially and/or thermally, from electrical components of the system. A gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer to urge dialysate through the dialyzer and blood back to the patient. The hemodialysis systems may include fluid handling device (s), actuated using a control fluid, optionally delivered using a detachable pump. Fluid handling devices may be generally rigid and of a spheroid shape, optionally with a diaphragm dividing the device into compartments.
Patent MX-2022005303-A (MX)
Title: Slow intraventricular delivery.
Inventor: CHENG SENG
IPC: A61B5/00
Filed: 2008-08-07
Abstract: Neurological diseases, including lysosomal storage diseases, can be successfully treated using intraventricular delivery of the therapeutic agents to bypass the blood-brain barrier. Similarly, diagnostic agents and anesthetic agents can be delivered to the brain in this manner. The administration can be performed slowly to achieve maximum effect. Such administration permits greater penetration of distal portions of the brain.
Patent MX-2022007259-A (MX)
Title: Il-2 orthologs and methods of use.
Inventor: MCCAULEY SCOTT ALAN
IPC: A61K38/20
Filed: 2020-12-11
Abstract: The present disclosure relates to hIL2 orthogonal ligands (IL2 orthologs) that specifically and selectively bind to the extracellular domain (ECD) a transmembrane polypeptide comprising of a modified hCD122 polypeptide. The binding of the hIL2 ortholog to the modified hCD122 polypeptide participates in the transduction pathway of intracellular signaling resulting in a biological activity of the native intracellular signaling patterns associated with hIL2 binding to either the intermediate or high affinity hIL2 receptor but which exhibits selectivity to an engineered cell expressing an hCD122 orthogonal receptor. The hIL2 orthologs of the present invention exhibit significantly reduced binding relative to their binding to the extracellular domain of wild type hCD122, either alone or when hCD122 is present in the form of an endogenous high or intermediate affinity hIL2 receptors.
Patent MX-2022008018-A (MX)
Title: Methods of treating heart failure with reduced ejection fraction with dapagliflozin.
Inventor: LANGKILDE ANNA MARIA
IPC: A61K45/06
Filed: 2020-07-13
Abstract: The present disclosure is directed to methods of treating patients with heart failure with reduced ejection fraction (HFrEF), with and without Type 2 diabetes, with an SGLT2 inhibitor, such as dapagliflozin. The methods disclosed herein can reduce the risk of a composite outcome of a first episode of worsening heart failure (hospitalization for heart failure or an urgent heart failure visit) or death from cardiovascular causes. Each of the three components of this composite outcome can also be reduced, as well as the total number of heart failure hospitalizations and deaths from cardiovascular causes. SGLT2 inhibitors, such as dapagliflozin, can also reduce a worsening of heart failure symptoms. The methods disclosed herein can also improve heart failure symptoms, health status, and quality of life.
Patent MX-2022011003-A (MX)
Title: Expansion of non-haematopoietic tissue-resident î³î´ t cells and uses of these cells.
Inventor: HAYDAY ADRIAN
IPC: C12N5/0783
Filed: 2018-04-26
Abstract: This invention relates to the expansion of non-haematopoietic tissue-resident Î³Î´ T cells in vitro by culturing lymphocytes obtained from non-haematopoietic tissue of humans or non-human animals in the presence of interleukin-2 (IL-2) and/or interleukin-15 (IL-15) and the absence of TCR activation or co-stimulation signals, without any direct contact with stromal or epithelial cells. Methods of non-haematopoietic tissue-resident Î³Î´ T cell expansion are provided, as well as populations of non-haematopoietic tissue-resident Î³Î´ T cells and uses thereof.
Patent MX-2022011127-A (MX)
Title: Organic water-soluble fertiliser with humic properties.
Inventor: NINNEMANN HORST
IPC: C05C3/00
Filed: 2021-03-09
Abstract: The invention relates to an organic water-soluble fertiliser, in solid form, with humic properties, comprising carbon and nitrogen with a carbon-to-nitrogen ratio of between 4 and 14, wherein more than 0% and up to 30% of the total nitrogen content is chemically bound as ammonia nitrogen, more than 0% and up to 20% of the total nitrogen content is chemically bound as easy-to-hydrolyse amide nitrogen and at least 50% of the total nitrogen content is chemically bound as difficult-to-hydrolyse amide nitrogen. The invention further relates to a method for producing an organic water-soluble fertiliser provided in solid form and to the use of such a water-soluble fertiliser.
Patent MX-2022012766-A (MX)
Title: Enhanced separation of solvolysis coproduct streams for chemical recycling.
Inventor: DEBRUIN BRUCE ROGER
IPC: C10G1/00
Filed: 2021-04-13
Abstract: Chemical recycling facilities for processing mixed waste plastic are provided herein. Such facilities have the capability of processing mixed plastic waste streams and utilize a variety of recycling facilities, such as, for example, solvolysis facility, a pyrolysis facility, a cracker facility, a partial oxidation gasification facility, an energy recovery facility, and a solidification facility. Streams from one or more of these individual facilities may be used as feed to one or more of the other facilities, thereby maximizing recovery of valuable chemical components and minimizing unusable waste streams.
Patent MX-2022013211-A (MX)
Title: Dispenser with mechanical transfer and method.
Inventor: RALEIGH EDWARD A
IPC: A47K10/32
Filed: 2020-04-21
Abstract: A dispenser for dispensing a roll of material is disclosed. The dispenser includes a rear housing and an openable cover. The rear-housing includes a roll transfer apparatus for transferring the roll of material from a first dispensing position to a second dispensing position. The roll transfer apparatus includes a transfer arm engaged with a transfer disk and a transfer latch capable of engaging and disengaging the transfer disk to facilitate movement of the roll of material from a first dispensing position to a second dispensing position. Also disclosed are methods for replacing a roll of material in a dispenser.
Patent MX-2022013243-A (MX)
Title: Communication infrastructure devices and support tools for intelligent residences or businesses and communicating method with and operating intelligent electrical devices.
Inventor: ELBERBAUM DAVID
IPC: H04B10/80
Filed: 2019-03-11
Abstract: A method and apparatus for propagating optical signals via a cascaded line of support devices for electrically powered wiring devices and low voltage IoTs and Ai devices, combined into homes and high-rise units for operating, controlling and reporting home automation via optical, electrical and wireless communication with no collision, by providing traffic control for signals propagation. The cascaded devices linked via plastic optical fiber or other optical cable are aided by a series of testers during installation and beyond, with the electrical and low voltage devices are installed by a plug-in action into the cascaded devices and removed by a pull hand tool.
Patent MX-NL03000012-A (MX)
Title: Steam condenser by means of air blowing and refrigerant flow.
Inventor: CARLOS ROA FLORES
IPC: F28F1/00
Filed: 2003-05-07
Abstract: A steam condenser by means of air blowing and refrigerant flow that reverses the natural upwardly direction of a steam flow and changes the input rate by means of atmospheric air blowing, in such a manner that said atmospheric stream is combined with the reversed steam flow, thereby producing a first heat exchange. Said combination of steam flow and air flow is passed through a plurality of cooling coils where a refrigerant flows therein, thereby producing a second heat exchange allowing the steam to condensate and the non-condensable streams to exit. Alternatively, a turboexpander is used at the steam flow inlet, which diminishes the steam temperature by expansion effects of the flow previous to the first heat exchange.
Patent MX-PA00001414-A (MX)
Title: Coated activated carbon.
Inventor: LAURENCE H HILTZIK
IPC: C08L101/00
Filed: 2000-02-09
Abstract: A process is disclosed for application of a polymer coating on a granular or shaped activated carbon to essentially eliminate or to significantly reduce product attrition by dusting without a reduction in adsorption velocity or capacity of the activated carbon. After the polymer coating has dried, any residual carbon dust is removed. New products resulting from the disclosed process also are disclosed.
Patent MX-PA00010471-A (MX)
Title: Brake shoe with friction management.
Inventor: BRUCE W SHUTE
IPC: F16D65/06
Filed: 2000-10-25
Abstract: The present invention provides a friction management brake shoe (10) adapted to engage the tread and the flange of a wheel of a railway vehicle via which the railway vehicle is guidably supported on a railed track. The friction management brake shoe (10) comprises a brake lining (6) affixed which has a braking surface engageable with the wheel tread of a wheel of a railway vehicle. The brake lining (6) includes a first friction composition material formed with at least one of a solid high positive friction modifier and a solid very high positive friction modifier which establish a required friction level between the wheel tread and the railed track.
Patent MX-PA00010566-A (MX)
Title: Matrices formed of polymer and hydrophobic compounds for use in drug delivery.
Inventor: BERNSTEIN HOWARD
IPC: A61K9/22
Filed: 1999-03-08
Abstract: A lipid or other hydrophobic or amphiphilic compound (collectively referred to herein as "hydrophobic compounds") is integrated into a polymeric matrix for drug delivery to alter drug release kinetics. In embodiments where the drug is water soluble, the drug is released over longer periods of time as compared to release from the polymeric matrix not incorporating the hydrophobic compound into the polymeric material. In contrast to methods in which a surfactant or lipid is added as an excipient, the hydrophobic compound is actually integrated into the polymeric matrix, thereby modifying the diffusion of water into the microparticle and diffusion of solubilized drug out of the matrix. The integrated hydrophobic compound also prolongs degradation of hydrolytically unstable polymers forming the matrix, further delaying release of encapsulated drug.