baber/WOPTO huggingface dataset:
Patent AU-694973-B2 (AU)
Title: Ultra sound method
Inventor: UNGER EVAN C
IPC: A61K41/00
Filed: 1997-01-17
Granted: 1998-08-06
Abstract: Gas, gaseous precursors and prefluorocarbons are presented as novel potentiators for ultrasonic hyperthermia. The gas, gaseous precursors and perfluorocarbons which may be administered into the vasculature, interstitially or into any body cavity are designed to accumulate in cancerous and diseased tissues. When therapeutic ultrasonic energy is applied to the diseased region heating is increased because of the greater effectiveness of sound energy absorption caused by these agents.
Patent AU-645668-B2 (AU)
Title: Mixed pyridine-2,4-and-2,5-dicarboxamides, a process for preparing them, the use thereof and pharmaceuticals based on these compounds
Inventor: BAADER EKKEHARD
IPC: A61K31/4402
Filed: 1992-03-17
Granted: 1994-01-20
Abstract: The invention relates to mixed pyridine-2,4- and -2,5-dicarboxylic acid diamides, the carboxylic acid amide group in position 2 being a primary acid amide. The said compounds are suitable for the inhibition of proline hydroxylase and lysine hydroxylase and are used as fibrosuppressants and immunosuppressants.
Patent AU-661475-B2 (AU)
Title: N-((4,5-dihydroxy- and 4,5,8-trihydroxy-9,10-dihydro-9,10-dioxo-2-anthracene-yl) carbonyl)amino acids useful in the therapy of osteoarticular affections
Inventor: MIAN MAURIZIO
IPC: C07C319/20
Filed: 1992-03-04
Granted: 1995-07-27
Abstract: PCT No. PCT/EP92/00479 Sec. 371 Date Oct. 6, 1993 Sec. 102(e) Date Oct. 6, 1993 PCT Filed Mar. 4, 1992 PCT Pub. No. WO92/16496 PCT Pub. Date Oct. 1, 1992.The present invention concerns a compound of formula (I)    <IMAGE>   wherein: X is selected from H and OH; R is a residue which, linked to the   mers and racemic mixtures thereof; and the pharmaceutically acceptable salts thereof. The invention further concerns a pharmaceutical composition which comprises the above compound or salts thereof and the use of the compound for treating an articular pathology.
Patent AU-585192-B2 (AU)
Title: Highly crystallized, molded product of polyarylene thioether
Inventor: KAWAKAMI YUKICHIKA
IPC: C08J5/18
Filed: 1988-03-30
Granted: 1989-06-08
Abstract: A highly crystallized, molded product of a polyarylene thioether is prepared by:   (1) stretching a molded product, consisting of a resin having as the main component a polyarylene thioether which contains not less than 70 mol% of the repeating unit <CHEM> and which has a degree of crystallization (measured by a density method) of not more than 15%, from 2 to 5 times in size in at least one direction, (2) contacting the stretched molded product with at least one organic solvent having a solubility parameter SP of from 8 to 12 or with a mixed solvent containing not less than 50% by weight of the said organic solvent at a temperature of from the solidifying point of the said organic solvent or mixed solvent to 130 DEG C, thereby preliminarily crystallizing the treated, molded product, until the degree of crystallization of the said polyarylene thioether has increased by not less than 6%, and (3) subjecting the preliminarily crystallized, molded product to thermal treatement at a temperature of from 140 to 300 DEG C until the degree of crystallization of the said polyarylene thioether reaches not less than 22%. h
Patent AU-597481-B2 (AU)
Title: A process for preparing a fiber reinforced resin matrix preform
Inventor: ALDRICH DONALD CHARLES
IPC: D04C1/06
Filed: 1988-03-31
Granted: 1990-05-31
Abstract: Process for preparing preforms and composite articles from carbon fiber reinforced matrix resins braided to shape on a mandrel and then converting to final composite article by fully or partially curing in a mold followed by post curing if required.
Patent AU-694691-B2 (AU)
Title: Method for making an electric motor winding
Inventor: MIHALKO EMIL S
IPC: H02K15/04
Filed: 1997-03-03
Granted: 1998-07-23
Abstract: A method for making a wound field for an electric motor, generator or alternator includes the steps continuously winding an insulated conductor into a coil, having a first plurality of windings wound in a first direction, and a second plurality of windings wound in a second direction opposite the first direction; flattening the coil into a two-layered flat web, and rolling the flat, two-layered web end-to-end into a cylindrical configuration. In one embodiment, a multiphase wound field can be made by winding a plurality of insulated conductors about a common axis to form a group of adjacent coil units. After the first group of coil units is wound, second and subsequent groups can be wound, in alternating directions of winding with respect to the first group, to form an elongate winding assembly. The entire assembly, is then flattened and rolled end-to-end. This create a wound field that is ready for insertion into a magnetic return path of an electric motor which has a higher density than was previously possible. As a result, current loss due to hysteresis and other features is materially reduced.
Patent AU-652047-B2 (AU)
Title: Reduction of ultra-violet photodamage with triesters of citric acid
Inventor: NATRAJ COLLUR VISWESWARIA
IPC: A61K6/00
Filed: 1992-05-01
Granted: 1994-08-11
Abstract: A composition suitable for topical application to human skin for reducing the damaging effects of ultra-violet light on skin comprises:   (a) an effective amount of a triester of citric acid having the structure (1): <CHEM>  where R<1>, R<2> and R<3> each independently represent a branched or unbranched alkyl,alkenyl, aryl, alkylaryl or arylakyl group, each said group being optionally substituted and having from 1 to 18 carbon atoms, R<4> represents -H, or a branched or unbranched saturated or unsaturated acyl, alkyl, aryl, alkylaryl or arylalkyl group, each said group being optionally substituted and having from 1 to 18 carbon atoms; and (b) a cosmetically acceptable vehicle for the citric acid ester; and   (c) an effective amount of a sunscreen agent, with the proviso that in the case where the sunscreen agent is an inorganic sunscreen, it has an average particle size of less than 100 mu m.
Patent AU-601848-B2 (AU)
Title: New anti-retroviral agents and delivery system
Inventor: WEINSTEIN JOHN N
IPC: A61K9/50
Filed: 1988-04-11
Granted: 1990-09-20
Abstract: The present invention provides a method for preventing or treating disease caused by retroviruses, particularly human immunodeficiency virus. Liposomes are prepared containing phosphorylated derivatives of nucleosides which act as chain-terminators of viral DNA. The phosphorylated nucleosides per se, without encapsulation in liposomes, do not readily enter cells. However, they are found to be effective if encapsulated in liposomes because they remain in liposomes longer, they do not escape easily from cells, and they constitute the active form for incorporation in viral DNA chains. When administered to a host, the liposomes are taken up by endocytic and phagocytic cells, which are important reservoirs of HIV infection. If coated with an appropriate ligand, such as an immunoglobulin molecule, liposomes containing the phosphorylated nucleosides can be directed to phagocytic cells, CD4-positive cells, or infected host cells.
Patent AU-718951-B2 (AU)
Title: Microorganisms and their use in treating animal feed and silage
Inventor: MANN STEPHEN PHILIP
IPC: A23K1/00
Filed: 1997-02-17
Granted: 2000-05-04
Abstract: The subject invention pertains to methods for treating silage which comprises adding to the silage a microorganism having the characteristic of Lactobacillus buchneri, NCIMB 40788, to produce a secondary metabolite as well as fatty acids normally produced in fermentation, and further comprising maintaining the silage closed for a period sufficient for the secondary metabolite to accumulate. This secondary metabolite has the ability to inhibit the growth of spoilage organisms including yeasts, molds and spore-forming bacteria.
Patent AU-547384-B2 (AU)
Title: Panel retainers for roof construction
Inventor: BARKER MICHAEL
IPC: E04D13/16
Filed: 1983-09-05
Granted: 1985-10-17
Abstract: Clips for retaining insulation boards for flat roofs are provided, the retainers comprising generally spaced apart parallel plate-like members joined to each other by two generally planar webs, the webs being disposed generally normal to each other and to the plate like members.
Patent AU-685609-B2 (AU)
Title: Compositions for the inhibition of protein hormone formation and uses thereof
Inventor: KRIEGLER MICHAEL P
IPC: C12N9/66
Filed: 1995-06-02
Granted: 1998-01-22
Abstract: The invention provides substantially purified TNF convertase, optionally said convertase being membrane associated and capable of converting TNF having a molecular weight of about 26,000 to one or more lower molecular weight TNF species, e.g. a lower molecular weight TNF species having a molecular weight of about 17,000 said convertase being inhibited by compounds selected from the group consisting of 3,4-dichloro-isocoumarin, elastinal and (1-((3-((acetyloxyl)-7-methoxy-8-oxy-8-oxo-5-thio-1-azabicyclo Ä4.2.0Ü oct-2-en-2-yl) carbonyl) morpholine, S,S-dioxide, (6R-cis).
Patent AU-604953-B2 (AU)
Title: Variants of bovine pancreatic trypsin inhibitor produced by recombinant dna technology, process, expression vector and recombinant host therefor and pharmaceutical use thereof
Inventor: AUERSWALD ERNST-AUGUST
IPC: A61K38/00
Filed: 1988-08-08
Granted: 1991-01-03
Abstract: Peptides essentially with the sequence of pancreatic bovine trypsin inhibitor (aprotinin) in which one or more amino acids in positions 15, 16, 17, 18, 34, 39 and 52 have been replaced by a naturally occurring amino acid are prepared by recombinant DNA technology. Also described are processes, expression vectors and recombinant hosts and the pharmaceutical use of the variants.
Patent AU-684627-B2 (AU)
Title: Microencapsulated compositon of chlorpyrifos or endosulfan
Inventor: MARCUS ARIE
IPC: A01N25/28
Filed: 1995-03-03
Granted: 1997-12-18
Abstract: The present invention relates to a microencapsulated chlorpyrifos or endosulfan composition comprising a polyurea shell and one or more photostable ultraviolet and visible light absorbent compound having a log molar extinction coefficient of from about 2 to 5 with respect to radiation having wave lengths in the range of about 310 to 450 nanometers, wherein said photostable ultraviolet and visible light absorbent compound does not react with the monomer used in building the polyurea shell. The result is a microencapsulated composition having unexpected long, extended insecticidal activity with high toxicity to target species and very low toxicity to non-target animals.
Patent AU-558259-B2 (AU)
Title: Valve seat assembly
Inventor: BURTON PHILIP JOSEPH
IPC: F16B21/18
Filed: 1983-11-11
Granted: 1987-01-22
Abstract: In order to provide an unobstructed outer face (7) on a retaining ring (4) forthe seal assembly of a butterfly valve, so that the face (7) can make an improved seal with an adjacent pipe end, the retaining ring (4) is held captive in the valve housing (1) by a wire ring (11), instead of by the usual screws which penetrate the face (7) and inhibit sealing with the pipe end. The wire ring is of regular polygonal shape such that the central portions (14) of its sides are received in a radially outwardly facing groove (10) in the retaining ring, and its corners (16) are received in a radially inwardly facing groove (8) in the housing. A helical lead-in groove (15) in the housing connects with the groove (8) to permit assembly of the retaining ring to the housing by a screwing action.
Patent AU-660186-B2 (AU)
Title: Dispenser for medical preparations
Inventor: THURELL PETER
IPC: A61J7/00
Filed: 1992-06-16
Granted: 1995-06-15
Abstract: Dispenser for medical preparations, comprising a rectangular box (1) having a bottom (2) and a top portion (3) in which a plurality of recesses (4) are formed, each covered by a lid (6) that is slidable in grooves (7) in the top portion (3) so as to be extractable in one direction; an insert (14) having several rows of compartments (15), each row being positioned under the corresponding recess (4) in the box and the compartments being adapted to accommodate the medical preparations; a cover (17) which closes an opening (1d) in one of the sides of the box and is removable to allow insertion and removal of the insert (14) through said opening; and a locking means (11) for locking all the lids (6) in the closed positions thereof, and for unlocking all the lids at the same time. The cover (17) is removable only after actuation of the locking means (11) for said unlocking of the lids (6). <IMAGE>
Patent AU-764731-B2 (AU)
Title: Tensioner with damping mechanism
Inventor: SERKH ALEXANDER
IPC: F16H7/12
Filed: 2000-12-13
Granted: 2003-08-28
Abstract: The invention comprises a tensioner that is particularly useful in micro-V front end accessory belt drive systems used in automotive applications where minimum tensioner bulk combined with maximum balancing and minimum pivot bushing wear in order to achieve maximum pulley alignment over the expected life of the tensioner. The belt tensioner of the invention is of the type with a base. A pivot-arm is attached to a cylindrical member that supports the pivot-arm and rotates about a pivot secured to the base. At least one sleeve-type bushing is positioned on the pivot and includes a bearing surface that supports the cylindrical member. A pulley is attached to the pivot-arm for engaging the belt and receives a belt load that generates a belt force component that is transmitted to the cylindrical member (hub load) A torsion spring having one end connected to the base and another end interconnected to a damping means generates a damping force component acting in the opposite direction as the belt force component. The damping means is mounted substantially between the pivot-arm and the bushing along a plane parallel with the pivot.
Patent AU-758376-B2 (AU)
Title: Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
Inventor: STELLA VALENTINO J
IPC: C08B37/16
Filed: 2000-01-11
Granted: 2003-03-20
Abstract: An osmotic solid pharmaceutical formulation for the controlled diffusional and osmotic delivery of a therapeutic agent to an environment of use comprising: 
a core comprising a physical mixture of a sulfoalkyl ether cyclodextrin, a therapeutic agent and a pharmaceutically acceptable carrier; and 
a membrane surrounding said core and comprising a film forming agent and a pore forming agent, said membrane having a passageway therethrough for communicating said core to an environment of use; 
wherein, 
a first portion of said therapeutic agent diffuses through said membrane and a second portion of said therapeutic agent passes through said passageway; and 
a major portion of said therapeutic agent is not complexed with said sulfoalkyl ether cyclodextrin.
Patent AU-666133-B2 (AU)
Title: Alkoxyphenylalkylamine derivative
Inventor: NAKAZATO ATSURO
IPC: C07C217/56
Filed: 1992-09-30
Granted: 1996-02-01
Abstract: An alkoxyphenylalkylamine derivative represented by general formula (I) and a salt thereof, wherein X<1> and X<2> may be the same or different from each other and each represents hydrogen, halogen, hydroxyl, or C1 to C5 alkoxy which may be substituted by phenyl; R<1> and R<2> may be the same or different from each other and each represents hydrogen or C1 to C7 alkyl which may be terminated with hydroxyl, carboxyl or alkoxycarbonyl, or alternatively R<1> and R<2> are combined with the adjacent nitrogen atoms to represent optionally substituted pyrrolidine, piperidino, piperazino, etc.; A represents phenyl which may be substituted by one to three arbitrary substituents selected among halogen, hydroxyl and C1 to C5 alkoxy, or similarly substituted thienyl; m represents an integer of 2 to 5; and n represents an integer of 1 to 7. The above compounds are useful in treating schizophrenia without causing extrapyramidal disorder and in treating problematic behaviours accompanying cerebrovascular disorder or senile dementia.
Patent AU-769347-B2 (AU)
Title: Biodegradable ph/thermosensitive hydrogels for sustained delivery of biologically active agents
Inventor: SHAH SUBODH
IPC: A61K38/18
Filed: 1999-12-10
Granted: 2004-01-22
Abstract: The present invention relates generally to the development of pharmaceutical compositions which provide for sustained release of biologically active polypeptides. More specifically, the invention relates to the use of pH/thermosensitive, biodegradable hydrogels, consisting of a A-B di block or A-B-A tri block copolymer of poly(d,l- or l-lactic acid) (PLA) or poly(lactide-co-glycolide) (PLGA) (block A) and polyethylene glycol (PEG) (block B), with ionizable functional groups on one or both ends of the polymer chains, for the sustained delivery of biologically active agents.
Patent AU-716633-B2 (AU)
Title: Amide derivatives
Inventor: OKAMURA TAKASHI
IPC: C07D495/04
Filed: 1997-06-02
Granted: 2000-03-02
Abstract: The invention provides amide derivatives which are useful as analgesics, anti-inflammatory agents, antimicrobial drugs, hypoglycemic agents, hypolipidemic agents, antihypertensive agents, anti-cancer agents, etc., the derivatives being represented by the formula <CHEM> wherein ring A represents a benzene ring, a naphthalene ring, a pyridine ring or a furan ring; R<4> represents a heterocyclic group selected from the group consisting of a lower alkyl-substituted thienoÄ3,2-dÜpyrimidin-4-yl group, an optionally substituted pyrazoloÄ1,5-aÜ-1,3,5-triazin-4-yl group, a pyrazoloÄ3,4-dÜpyrimidin-4-yl group substituted at the 6-position and a purin-6-yl group substituted at the 2-position; and R<5> represents a hydrogen atom or a group represented by <CHEM>
Patent AU-663142-B2 (AU)
Title: Radiation-cured liquid coating compounds for glass surfaces
Inventor: SCHUNCK STEPHAN
IPC: C03C17/28
Filed: 1992-11-24
Granted: 1995-09-28
Abstract: PCT No. PCT/EP92/02699 Sec. 371 Date May 26, 1994 Sec. 102(e) Date May 26, 1994 PCT Filed Nov. 24, 1992 PCT Pub. No. WO93/11080 PCT Pub. Date Jun. 10, 1993.The present invention is directed to a beam-curable coating composition for coating glass surfaces, particularly, optical glass fibers. The resultant coatings show slight or no loss of adhesion after exposure to moisture. The coating composition includes ethylenically unsaturated polyurethane, ethylenically unsaturated monomer, photoinitiator and a silane compound. The silane compound is an azidosilane and is added to improve adhesion of the coating agents exposed to moisture. Optionally, aminoalkoxysilanes may also be included.
Patent AU-782911-B2 (AU)
Title: Mower comprising a windrow grouping mechanism
Inventor: WALCH MARTIN
IPC: A01D57/00
Filed: 2002-04-05
Granted: 2005-09-08
Abstract: The mower, comprising a chassis (1) with a cutter (5) and a swathing mechanism with lengthwise (17) and transverse (18) conveyors, has the lengthwise conveyor made with at least one and preferably three identical rollers (221, 231) with their lengthwise axes lying perpendicular to the mower's direction of travel and rotated to carry the cut crop to the rear. The rollers are positioned one after another in the same plane, inclined downwards at the front to pick up the crop as it is cut, and each roller is in two halves, situated on either side of the mower's median vertical plane. One of them is driven by a motor and the others by a transmission system.
Patent AU-763993-B2 (AU)
Title: Methods of identifying bacterial genes that are incompatible with bacterial pathogenicity, and the use of such genes, such as (cadA), to reduce pathogenicity in a bacteria or to combat pathogenic bacterial infections
Inventor: MAURELLI ANTHONY T
IPC: A61K31/455
Filed: 1999-03-31
Granted: 2003-08-07
Abstract: "Black holes" in the genomes of bacterial pathogens represent deletions of "anti-virulence" genes, i.e. genes that are detrimental to a pathogenic lifestyle. Identification of the missing genetic loci in the "black hole" identifies genes that are incompatible with the bacteria's pathogenicity. These genes, their gene products, and compounds generated by the enzymatic action of these gene products represent potential new compounds that are inhibitory to the bacterial pathogen and thus useful as pharmaceuticals. The utility of this concept is demonstrated in the missing gene for lysine decarboxylase, and the resulting inhibitory activity of cadaverine (the diaminoalkyl reaction product of lysine decarboxylase) on the Shigella enterotoxins. Diaminoalkyl compounds are therefore potent inhibitors of E. coli and Shigella spp. enterotoxins. Lysine decarboxylase generated from the gene cadA results in attenuation of the enterotoxic effects. New methods of use of diaminoalkyl compounds as medicaments are described. New uses of genetic constructs containing a cadA sequence, or other "anti-virulence" gene, for biochemical probes, for toxin receptor identification, and for pharmaceutical discovery are described. Additional uses are described for vaccines and DNA vaccine delivery.
Patent AU-609310-B2 (AU)
Title: Method for treating alcoholism by extinguishing the alcohol-drinking response
Inventor: SINCLAIR JOHN DAVID
IPC: A61K31/00
Filed: 1989-06-13
Granted: 1991-04-26
Abstract: Described is the use of opiate antagonists for the preparation of pharmaceutical compositions to be administered simultaneously or separately sequentially with alcohol in the treatment of alcoholism. These pharmaceutical compositions are capable of extinguishing the alcohol-drinking response of alcoholics during a relatively short period of time by having the alcoholics drink alcoholic beverages repeatedly while the opiate antagonist contained in said pharmaceutical composition blocks the positive reinforcement effects of ethanol in the brain.
Patent AU-576545-B2 (AU)
Title: 4-methylamino-1,2,4-triazin-5-ones
Inventor: BOHNER BEAT
IPC: A01N43/64
Filed: 1985-01-10
Granted: 1988-09-01
Abstract: The invention relates to 4-methylamino-1,2,4-triazin-5-one of the formula I    <IMAGE>  (I)  wherein R1 is C3-C8 cycloalkyl or C3-C8 cycloalkyl which is substituted by C1-C4alkyl; C3-C8halocycloalkyl, C3-C8alkyl, C3-C8haloalkyl, 2-furyl, 2-thienyl, phenyl, benzyl, or phenyl or benzyl each substituted by one or more members selected from the group consisting of halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy or C1-C4haloalkoxy, R2 is hydrogen or methyl, and R3 is cyclopropyl, cyclopropylmethyl, C1-C4alkyl, C3-C4alkenyl or C3-C4alkynyl. These compounds have selective herbicidal properties and are therefore pre-eminently suitable for controlling weeds in crops of useful plants, for example in cereals, maize, soybeans and sugar cane. They are also suitable for controlling harmful insects.
Patent AU-612866-B2 (AU)
Title: Method and apparatus for conveying materials
Inventor: GOUGH GEORGE TERAH
IPC: B65G17/16
Filed: 1989-07-18
Granted: 1991-07-18
Abstract: A conveyor system comprising a series of buckets (10) supported by entrainment means such as a chain (15A,15B) along a predetermined endless path having straight portions (19,20,21) and at least one internal curve (28C). An individual pivoting arm (12) supports a respective bucket (10) on the chain (15A,15B). Each pivoting arm (12) is pivotally attached to the entrainment means (15A,15B) at a first end in fixed orientation to the chain (15A,15B), and pivotally supports the bucket (10) at the opposite second end. A chain guide (50 or 52) engages the chain (15A,15B) in advance of an internal curve (28C) in the path to cause the buckets (10) to move apart and then allow the second end of the pivoting arm (12) to which the bucket (10) is attached (at 14) to pivot outwardly and the buckets (10) in turn to follow a diverging curved path (27A) of greater radius than the radius of the curve (28C) in the path being transited and thereby space the buckets (10) further apart prior to negotiating the internal curve (28C) in the path than when the buckets (10) are proceeding along a straight portion (19,20,21) of the path.