baber/WOPTO huggingface dataset:
Patent DK-1392312-T3 (DK)
Inventor: GILLESPIE ROGER JOHN
IPC: A61P25/24
Filed: 2002-01-10
Granted: 2009-06-15
Abstract: The use of a compound of formula (I): wherein R1 is selected from H, alkyl, aryl, alkoxy, aryloxy, alkylthio, arylthio, halogen, CN, NR5R6, NR4COR5, NR4CONR5R6, NR4CO2R7 and NR4SO2R7; R2 is selected from aryl attached via an unsaturated carbon; R3 is selected from H, alkyl, COR5, CO2R7, CONR5R6, CONR4NR5R6 and SO2R7; R4, R5 and R6 are independently selected from H, alkyl and aryl or where R5 and R6 are in an NR5R6 group, R5 and R6 may be linked to form a heterocyclic group, or where R4, R5 and R6 are in a (CONR4NR5R6) group, R4 and R5 may be linked to form a heterocyclic group; and R7 is selected from alkyl and aryl, or a pharmaceutically acceptable salt thereof or prodrug thereof, in the treatment or prevention of a disorder in which the blocking of purine receptors, particularly adenosine receptors and more particularly A2A receptors, may be beneficial, particularly wherein said disorder is a movement disorder such as Parkinson's disease or said disorder is depression, cognitive or memory impairment, acute or chronic pain, ADHD or narcolepsy, or for neuroprotection in a subject; compounds of formula (I) for use in therapy; and novel compounds of formula (I) per se.
Patent DK-1381850-T3 (DK)
Inventor: BRUINS HANS JOACHIM
IPC: G01N21/85
Filed: 2002-04-22
Granted: 2010-05-03
Abstract: The invention relates to a method for measuring spectroscopic properties in cereals or cereal products, whereby the cereals or the cereal products are transported by a feeder device into a fall shaft where they undergo spectroscopic parameter detection on a measuring path. A locking device which is arranged downstream from the measuring path in the fall shaft is actuated in such a way that the sample is alternatively displaced and left in a static position in the fall shaft. Detection of the spectroscopic parameters is carried out on the static sample.
Patent DK-1476694-T3 (DK)
Inventor: JELTSCH THOMAS
IPC: F17C1/00
Filed: 2003-02-20
Granted: 2007-04-10
Abstract: The invention relates to a pressurised container (1) comprising at least one tubular connection (2) to an opening in the container wall. According to the invention, the cross-sections of the opening and at least the tubular connection (2) in the vicinity of the opening are oval-shaped, the large axis of the oval shape being aligned with the direction of the first primary stress, which would be generated if the pressurised container (1) were subjected to an internal pressure at the connection point without the opening and the connection (2). This permits both the local and global maximum comparison stress to be advantageously reduced in the component when the latter is subjected to a pressure and/or the stress to be displaced into areas, in which it is not as critical. The invention can be used in a particularly advantageous manner for injection-moulded parts consisting of plastic, as joint lines in many geometrical forms cannot be avoided in precisely those areas where the most stress occurs as a result of the geometry of said parts.
Patent DK-1486312-T3 (DK)
Inventor: MAENNER HANS PETER
IPC: B29C45/77
Filed: 2004-06-02
Granted: 2006-01-02
Abstract: The data memory (4) is demountable from the mold. A sensor (6) senses the de mounted state and a timer determines its duration.
Patent DK-1648654-T3 (DK)
Inventor: RISSLER PER
IPC: F28D9/00
Filed: 2004-06-09
Granted: 2009-11-23
Abstract: The plate is made with a double-wall construction, allowing any leaking fluid to be drained away towards the plate periphery.
Patent DK-1732515-T3 (DK)
Inventor: NILSSON THOMAS
IPC: A61K9/14
Filed: 2005-03-23
Granted: 2008-11-10
Abstract: A dry powder medicament preparation is disclosed. Also methods of forming and loading metered doses of the preparation into dose containers intended for insertion into a dry powder inhaler are disclosed. The preparation is adapted for a dose forming process, which may be based on volumetric filling or electro-dynamic deposition of the powder particles, such that a metered dose of the preparation is characterized by having at least one load of held-together particles joined in a macrostructure of predefined dimensions and presenting an intended mechanical strength. The pharmacologically active ingredient presents at least 50% by mass of particles in a typical aerodynamic diameter range from 1 to 5 mum. Furthermore, a dose thus formed is then loaded into a high barrier container.
Patent DK-1671541-T3 (DK)
Inventor: Lützeler Michael
IPC: A01N33/08
Filed: 2001-09-18
Granted: 2016-07-25
Abstract: A disinfectant composition (A), containing (a) an N,N-bis-(3-aminopropyl) higher alkylamine (I) and/or a benzyl or higher alkyl-substituted quaternary ammonium salt (II), additionally contains (b) at least one mono-, di or trialkanolamine (III) or its salt, at an (a) : (b) weight ratio of 1-20 : 20-1. A disinfectant composition (A) contains (a) an amine of formula (I) and/or a quaternary ammonium salt of formula (II) and (b) at least one alkanolamine of formula (III) or its salt, at an (a) : (b) weight ratio of 1-20 : 20-1. [Image] [Image] [Image] R 16-18C alkyl; R 2benzyl or 6-18C alkyl; R 31-18C alkyl or -(CH 2CH 2O) nR 6; n : 1-20; R 4, R 51-4C alkyl; R 6H or optionally substituted phenyl; A ->monovalent anion (or an equivalent of a polyvalent anion) of an inorganic or organic acid; m, o, p : 2 or 3; and x, y : 0 or 1. ACTIVITY : Fungicide; antibacterial. A disinfectant/cleaner concentrate contained (by weight) 5.0% didecyl dimethylammonium chloride, 2.0% N,N-bis-(3-aminopropyl)-dodecylamine, 5.0% monoethanolamine (IIIa), 5.0% Genapol T250 (RTM; tallow fatty alcohol polyglycol ether with 25 moles ethylene oxide), 0.5% sodium metasilicate, 0.5% sodium carbonate, 2.0% Trilon M (RTM; trisodium methylglycine-diacetate; 40% solution) and water to 100%. A 1% aqueous solution of the concentrate reduced the Aspergillus niger ATCC 16404 count by 4.1 logarithmic units after a contact time of 15 minutes at 20 [deg]C, whereas a control composition without (IIIa) had no significant antimicrobial effect under the same conditions. MECHANISM OF ACTION : None given in the source material.
Patent DK-1769810-T3 (DK)
Inventor: FOSTER DAVID
IPC: A61M1/02
Filed: 2002-04-17
Granted: 2010-07-12
Abstract: An apparatus for collecting blood from a patient, comprising a collection vessel having a pleated, compressible body, the vessel having an inlet port which comprises two port connections, the first being adapted to be connected to a patient line for drawing blood from a patient and the second being adapted to be attached to a constant vacuum, wherein the collection vessel comprises an outlet port adapted to be connected to a blood collection bag.
Patent DK-1874825-T3 (DK)
Inventor: JUNGBAUER ALOIS
IPC: C07K1/22
Filed: 2006-04-25
Granted: 2010-07-05
Abstract: The invention relates to a process for the recombinant production of a heterologous polypeptide of interest, comprising, 
(i) cultivation of a bacterial host cell which is transformed with an expression vector which comprises a nucleic acid molecule which codes for a fusion polypeptide, the fusion polypeptide comprising a derivative of an autoprotease N pro  of Pestivirus, wherein at least one cysteine residue of the naturally occuring autoprotease N pro  of Pestivirus is replaced by another amino acid residue, and a second polypeptide which is connected to the first polypeptide at the C-terminus of the first polypeptide in a manner such, that the second polypeptide is capable of being cleaved from the fusion polypeptide by the autoproteolytic activity of the first polypeptide, said second polypeptide being a heterologous polypeptide, wherein cultivation occurs under conditions which cause expression of the fusion polypeptide and formation of corresponding cytoplasmic inclusion bodies, 
(ii) isolation of the inclusion bodies from the host cell, 
(iii) solubilization of the isolated inclusion bodies, 
(iv) induction of autoproteolytic cleavage of the heterologous polypeptide of interest from the fusion polypeptide, and 
(v) isolation of the cleaved heterologous polypeptide of interest.
Patent DK-1937639-T3 (DK)
Inventor: PATTERSON BRIAN DOUGLAS
IPC: A61K31/4406
Filed: 2006-09-11
Granted: 2010-05-10
Abstract: The present invention provides compounds of formula (I), or pharmaceutically acceptable salts or solvates thereof, methods for their preparation, methods for their use, and pharmaceutical formulations comprising them.
Patent DK-1963278-T3 (DK)
Inventor: MERLA BEATRIX
IPC: A61P25/04
Filed: 2006-12-19
Granted: 2010-03-29
Abstract: Imidazoline derivatives (I) are new. Imidazoline derivatives of formula (I) and their isomers and salts are new. n : 0-2; R 1>(un)saturated 1-8C alkyl, (un)saturated 3-8C cycloalkyl, aryl(1-3C)alkyl or heteroaryl(1-3C)alkyl, all optionally substituted; R 2>aryl, heteroaryl or aryl(1-3C)alkyl, all optionally substituted; R 3>(un)saturated 1-8C alkyl or aryl(1-3C)alkyl, both optionally substituted; R 4>H, 1-4C alkyl or aryl(1-3C)alkyl; R 5>, R 6>H or optionally substituted (un)saturated 1-8C alkyl, but not both H, or R 5>+R 6> is CH 2CH 2OCH 2CH 2 or (CH 2) m; m : 3-6. Independent claims are also included for: (1) a process for preparing (I); (2) aldehydes of formula B. [Image] [Image] ACTIVITY : Analgesic; Antidepressant; Uropathic; Antidiarrheic; Antipruritic; Antialcoholic; Antiaddictive; Tranquilizer. MECHANISM OF ACTION : mu -Opiate receptor inhibitor. Methyl 1-cyclohexyl-5-(4-(dimethylamino(3-fluorophenyl)methyl)-4-isobutyl-4,5-dihydro-1H-imidazole-4-carboxylate gave 84% inhibition of human mu -opiate receptor activity at a concentration of 1 mu M.
Patent DK-2212297-T3 (DK)
Inventor: ALLGEIER HANS
IPC: A61P9/00
Filed: 2008-10-13
Granted: 2011-09-05
Abstract: Compounds of general Formula I: wherein R1, R2, R3, x, A and Ra are as defined herein are inhibitors of cyclin-dependent kinases and are useful for preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases.
Patent DK-2222865-T3 (DK)
Inventor: MARGEOT ANTOINE
IPC: C12N9/42
Filed: 2008-11-06
Granted: 2011-08-15
Abstract: Process for producing alcohol from pretreated lignocellulosic biomass comprises enzymatic hydrolysis of the biomass carried out with cellulolytic and/or hemicellulolytic enzymes produced using at least an effluent obtained from a production process of ethanol using sugar plant as raw material.
Patent DK-2088200-T3 (DK)
Inventor: DUNN-COLEMAN NIGEL
IPC: C12N9/18
Filed: 2001-11-16
Granted: 2012-04-23
Abstract: Described herein are methods to enhance the production of more highly fermentable carbohydrates in plants, especially forage grasses. The invention provides for transgenic plants transformed with expression vectors containing a DNA sequence encoding ferulic acid esterase I from  Aspergillus,  preferably  A. niger.  The expression vectors may optionally comprise a DNA sequence encoding xylanase from  Trichoderma,  preferably  T. reesei . Expression of the enzyme(s) is targeted to specific cellular compartments, in specific tissues and under specific environmental conditions. Uses of this invention include, but are not limited to, forage with improved digestibility for livestock, and enhanced biomass conversion.
Patent DK-2350427-T3 (DK)
Inventor: ALVAERN JOSTEIN
IPC: E21B33/076
Filed: 2009-11-19
Granted: 2018-03-26
Abstract: Device for transfer of equipment for a wireline operation in a well connected to a drilling derrick via a top drive. The device comprises a beam structured for releasable connection to said top drive; wherein the beam is structured in a manner allowing it to extend, when in its position of use, transversely relative to a centre line between the top drive and the well; wherein the beam is provided with at least one hoisting device with a lifting line for vertical movement of said equipment; wherein a support point for the lifting line is connected to the beam and is structured so as to be movable in the longitudinal direction of the beam, whereby said equipment may be moved horizontally relative to said centre line; and wherein said hoisting device and support point are structured for remote-controlled operation.
Patent DK-2213179-T3 (DK)
Inventor: MANZON DANIELE
IPC: A23G1/26
Filed: 2010-01-19
Granted: 2012-07-09
Abstract: The tempering apparatus for chocolate masses or like masses that are contained in a casting plate (3), comprises a device for the upward movement of the casting plate, a device for the downward movement of the casting plate, an inlet opening for the filled casting plate, a device for stacking and lifting the casting plate, and a device for upwardly moving and removing the treated casting plate. The casting plate is placed on movable transverse struts (4) in the interior of the tempering apparatus with their ends and a support (6) is provided at the ends of the transverse struts. The tempering apparatus for chocolate masses or like masses that are contained in a casting plate (3), comprises a device for the upward movement of the casting plate, a device for the downward movement of the casting plate, an inlet opening for the filled casting plate, a device for stacking and lifting the casting plate, and a device for upwardly moving and removing the treated casting plate. The casting plate is placed on movable transverse struts (4) in the interior of the tempering apparatus with their ends and a support (6) is provided at the ends of the transverse struts. The support has a conical recess (7) at its upper side with a tapered end piece (6) and at its lower side. A constant free space remains between the stacked transverse struts. During the conveying process in the tempering apparatus, the tapered end and the underlying end of the support are connected with the conical recess of the overlying support, where the support has a length, which determines the free space between the two transverse struts arranged parallel to each other. The transverse struts receive the casting plate with the material to be processed, and are U-shapedly formed in the cross-section.
Patent DK-2488703-T3 (DK)
Inventor: JUNG BOUDEWIJN CASPER
IPC: E02D13/00
Filed: 2010-10-08
Granted: 2018-04-23
Abstract: The present invention relates to a device for passively reducing the noise vibrations in a liquid resulting from a sound source (62) which is arranged below the liquid level of a body of water (w), the device comprising a noise-insulating pipe (1) which is designed to be arranged around the sound source, wherein the pipe comprises a number of telescopically extendable and retractable pipe sections, (2,3,4) fastening means for attaching at least one first and one second pipe section to one another in extended and/or retracted position, wherein the fastening means are designed to allow the mutual displacement of the pipe sections in a starting position and to attach the pipe sections to one another in a fastening position, and wherein the fastening means are also designed to keep the first (2) and second pipe sections (3) substantially acoustically disconnected in the fastening position.
Patent DK-2476435-T3 (DK)
Inventor: SAINT-REMY JEAN-MARIE
IPC: A61K35/17
Filed: 2007-08-13
Granted: 2018-03-05
Abstract: The present invention provides novel peptides and homologues thereof. The peptides of the invention comprise (i) a T-cell epitope of an antigen (self or non-self) with a potential to trigger an immune reaction presented by a class II major histocompatibility complex (MHC) determinant and recognised by CD4+ T cell more specifically of an allergen or auto-antigen, coupled, optionally through the use of a linker to (ii) an amino acid sequence having a reducing activity, such as a thioreductase sequence. The peptides of the invention have been shown to be useful a medicine, more in particular for the prevention or treatment of immune disorders, more specifically of allergic disorders or autoimmune diseases. The present invention thus provides for the use of said peptides for the manufacture of a medicament for the prevention or treatment of an immune disorder and further provides for methods of treatment or preventing immune disorders by using said peptides. The present invention also provides for compositions comprising said peptides.
Patent DK-0381986-T3 (DK)
Inventor: NEGELE MICHAEL DR
IPC: C11D7/50
Filed: 1990-01-23
Granted: 1994-08-08
Abstract: Use of polyfluoroalkanes of the formula CX3-CY2-R     (I> in which X radicals on the same C atom stand for hydrogen and/or fluorine, Y radicals on the same C atom stand for hydrogen, fluorine and/or CF3 and R stands for CH2F, CHF2, CH3, CF3, CF2-CH3, CF2CH2F, CH2-CH3, CH2-CH2-CH3 or -CH(CH3)-CH3 and a molecule of the formula (I) contains at least two fluorine atoms, as propellant gases. o
Patent DK-0384370-T3 (DK)
Inventor: LANG HANS-JOCHEN DR
IPC: A61P3/08
Filed: 1990-02-20
Granted: 1994-03-07
Abstract: Pyrimidine derivatives of the formula I   <IMAGE> I  in which R1, R2, R3, R4 and R5 have the indicated meanings, the salts thereof, and a process for the preparation thereof are described. Because of their sorbitol-accumulating activity, they are suitable as a tool in a pharmacological screening model for aldose reductase inhibitors.
Patent DK-0437759-T3 (DK)
Inventor: DETHIER LOUIS ING
IPC: F23H3/02
Filed: 1990-12-17
Granted: 1993-08-23
Abstract: A grate for a fuel boiler, consisting of plates arranged stepwise or in a cascading fashion, with at least two fixed plates and a movable plate disposed between the two fixed plates. The movable plate is capable of reciprocating to and fro and is provided with an appropriate drive. Combustion air passes through the interspace between the movable and fixed plates and allows for controlled and complete combustion of the fuel. The fixed plates are fastened to a common first holder and the movable plates are fastened to a common second holder. The fastening of each plate to its individual holder is vertically-adjustable. Preferably, the air utilized for combustion of the fuel is only that which has passed through, and preferably been drawn through, the interspace between the movable and fixed plates.
Patent DK-0391485-T3 (DK)
Inventor: KLOK ROBBERT
IPC: B01J31/12
Filed: 1990-04-03
Granted: 1994-04-11
Abstract: The invention pertains to the production of high-purity fatty-acid lower-alkyl mono-esters which comprises a first transesterification step between glycerol fatty-acid esters and a lower alcohol, a separation step wherein the reaction product of the esterification step is separated into glycerol-rich and fatty-acid lower-alkyl mono-ester rich fractions, a second esterification step in which all glycerol and fatty-acid glycerolesters of the fatty-acid lower-alkyl mono-ester rich fraction are esterified to the corresponding fatty-acid triglycerolesters, and a recovery step wherein said fatty-acid lower-alkyl mono-esters are recovered.
Patent DK-0423923-T3 (DK)
Inventor: CHILI DANILO
IPC: C02F1/42
Filed: 1990-07-06
Granted: 1993-12-20
Abstract: Water treatment apparatus having a raw water inlet and a treated water outlet and at least a first and second water treatment tank plus conduit means for passing water from the inlet to the outlet through the first and second tanks in parallel flow relation. The tanks are automatically regenerated in sequential, alternating intermittent manner in response to predetermined criteria. The tank being regenerated is connected to prevent flow from said tank through the outlet, while the tank not being regenerated is connected to provide flow through the outlet. Accordingly, continuous water treatment, with alternating, intermittent regeneration of the tanks, may be provided.
Patent DK-0467991-T3 (DK)
Inventor: FRANCIS CHAO
IPC: A61K35/14
Filed: 1990-04-12
Granted: 1999-02-01
Abstract: A platelet membrane fragment preparation having procoagulant activity that is non-antigenic with respect to class I, HLA determinants.
Patent DK-0484679-T3 (DK)
Inventor: ALTEN KURT
IPC: E01B25/00
Filed: 1991-10-07
Granted: 1995-08-07
Abstract: The invention starts from transfer bridges, the bridge plate (18) of which can be swung from a vertical position of rest behind the tracks (5) into a horizontal operative position, in which the bridge plate (18) rests with its free end on a ramp (1), the point of articulation of the bridge plate (18) being mounted on a vertical jib of an undercarriage (9) located behind the tracks (5). In order to obtain a comparatively large span of the bridge in low spaces, as a result of the invention, the point of articulation of the bridge plate (18) is mounted on the jib so as to be raisable and lowerable, the point of articulation being lowerable during the swing-up of the bridge plate (18) from the operative position into the approximately vertical position of rest and being raisable during the swing-down of the bridge plate (18) from the approximately vertical position of rest into the operative position. 
<IMAGE>
Patent DK-0482489-T3 (DK)
Inventor: CARRARA SERGIO
IPC: F16J15/22
Filed: 1991-10-16
Granted: 1996-09-23
Abstract: A compound for making packing seals (4) comprises a plurality of yarns (3) braided together and consisting of twisted spinning of pieces of different and random lengths of stainless steel filaments (1) and filaments of other materials (2) such as carbon, pure graphite, aramidic fibers and others. The technique used comprises an action of tear spinning or intermittant twisting and traction on said filaments (1). <IMAGE>
Patent DK-0527824-T3 (DK)
Inventor: GEKE JUERGEN
IPC: C11D1/72
Filed: 1991-04-30
Granted: 1995-06-19
Abstract: PCT No. PCT/EP91/00823 Sec. 371 Date Nov. 9, 1992 Sec. 102(e) Date Nov. 9, 1992 PCT Filed Apr. 30, 1991 PCT Pub. No. WO91/17233 PCT Pub. Date Nov. 14, 1991.The present invention relates to the use for cleaning hard surfaces of a combination of ionic and nonionic surfactants containing (a) at least one quaternary ammonium compound having the general formula (I) R1(-CHOH-CHR2)n-N+R3R4R5X-(I)  (b) at least one alk(en)yl polyethylene glycol mixed ether having the general formula (II): R6-O-(CH2CH2-O)2-R7(II).
Patent DK-0607128-T3 (DK)
Inventor: GEISSLINGER GERD
IPC: C07C57/58
Filed: 1991-08-19
Granted: 1998-04-14
Abstract: The present invention provides a medicament for the treatment of painful and/or inflammatory diseases and/or of fever with flurbiprofen, wherein the flurbiprofen is pure or preponderantly R(-)-flurbiprofen worked up in combination with conventional pharmaceutical carriers and adjuvants, to give a medicament.
Patent DK-0552226-T3 (DK)
Inventor: MARKLE RICHARD A
IPC: C08L67/04
Filed: 1991-09-18
Granted: 1994-09-12
Abstract: The present invention is directed to a method for making L-lactide from aqueous L-lactic acid. Aqueous lactic acid feed for present purposes comprehends an aqueous mixture of one or more of L1A, L2A, and L3A, optionally with LD being present. L-lactic acid is the preferred feed configuration for making L-lactide, and is to be understood even though the configuration symbol is not used throughout this application. Aqueous lactic acid feed is treated for removal of water therefrom until a degree of polymerization (DP) not substantially above about 2 is reached. The treatment then is ceased to produce a crude LD product. LD then is separated from the crude LD product. A preferred treatment involves heating the feed at elevated temperature to remove water. LD can be separated from the crude LD product by a variety of techniques to produce an LD-depleted product. This LD-depleted product, optionally augmented with additional aqueous lactic acid and/or water then can be readmitted to the process for making additional lactide. This cyclic or recycle process embodiment of the present invention enables very high lactide conversions to be realized.