baber/WOPTO huggingface dataset:
Patent CA-2648064-A1 (CA)
Title: Regulated expression of recombinant proteins from adeno-associated viral vectors
Inventor: JOOSS KARIN
IPC: C07H21/04
Filed: 2007-03-29
Abstract: Single AAV vector constructs for regulated expression of an immunoglobulin molecule or fragment thereof and methods of making and using the same are described. The AAV vectors comprise a regulated promoter operably linked to the coding sequence for a first and second immunoglobulin coding sequence, a sequence encoding a self-processing cleavage site between the coding sequence for the first and second immunoglobulin coding sequence and a additional proteolytic cleavage site, which provides a means to remove the self processing peptide sequenc from an expressed immunoglobulin molecule or fragment thereof. The vector constructs find utility in enhanced production of biologically active immunoglobulins or fragments thereof in vitro and in vivo.
Patent CA-2651561-A1 (CA)
Title: Self-contained multi-sprayer
Inventor: WAEBER KENNETH R
IPC: B08B3/02
Filed: 2007-05-10
Abstract: A pressure sprayer (20) includes an accumulator vessel (142) adapted to hold a pressurized fluid therein and a container (68) that is configured to hold a chemical concentrate. A motor (156) in fluid communication with the accumulator vessel and the container (68) is adapted to be driven by the pressurized fluid and to pump the pressurized fluid and the chemical concentrate. A chamber (194) is adapted to receive the chemical concentrate and the pressurized fluid from the motor (156) to form a chemical solution. A nozzle is in fluid communication with the chamber (194).
Patent CA-2651837-A1 (CA)
Title: Magnetic element temperature sensors
Inventor: CLOTHIER BRIAN L
IPC: G01K7/00
Filed: 2007-01-03
Abstract: Small, low-cost wireless temperature sensors (26, 64, 96) are provided for sensing the temperature of an object (44). The temperature sensors (26, 64, 96) preferably include a plurality of individual, magnetically susceptible temperature sensor elements (28-34, 66, 92), as well as optional magnetic field-responsive data elements (38, 40, 20) adapted for attachment to object (44) or to a substrate (82) in turn attached to object (44). The temperature sensor elements (28-34, 66, 92) preferably have magnetic bodies (22, 70) exhibiting a re-magnetization response under the influence of an applied alternating magnetic field, which is different below and above a set point temperature, normally the Curie temperature of the magnetic body (22) or an adjacent sheath (74, 94). The temperature sensors (26, 64, 96) are used in conjunction with a detector (46) operable to generate a magnetic field of magnitude sufficient to cause re-magnetization responses of the temperature sensor elements (28-34, 66, 92) and optional data elements (38, 40, 20), to detect such responses, and to use the detected responses to determine the temperature of object (44) by means of a decoding algorithm. The temperature sensors (26, 64, 96) can be used in closed-loop heating systems (98) capable of controlling the heating of an object (114).
Patent CA-2652512-A1 (CA)
Inventor: HUBBARD DENNIS
IPC: A61B17/12
Filed: 2007-05-22
Abstract: A tissue suturing apparatus and method which comprises two needles mounted to the housing of the device. The first needle contains a suture which is passed through the tissue and received by the second needle. The second needle receives the suture leading end and removes it from the inside of the tissue.
Patent CA-2652557-A1 (CA)
Title: Method of preparing carbonaceous anode materials and using same
Inventor: CAREL MARK W
IPC: H01M4/58
Filed: 2007-05-22
Abstract: A method for the production of carbon particles comprising selecting a precursor material, sizing said precursor material, stabilizing said precursor material, carbonizing said precursor material, and graphitizing said precursor material, wherein the precursor material has a volatile matter content of from about 5 wt.% to about 60 wt.%. A method for the production of electrode materials comprising selecting a precursor material, sizing said precursor material, stabilizing said precursor material, carbonizing said precursor material, and graphitizing said precursor material, wherein said electrode material has an average particle size of from about 1 µm to about 50 µm, a fixed carbon content of greater than about 80 wt.%, and a graphitic structure. A carbon particle having an average particle size of from about 1 µm to about 50 µm, a degree of stabilization of from about 0.1 wt.% to about 10 wt.%, a fixed carbon content of greater than about 80 wt.%, and a graphitic structure.
Patent CA-2653333-A1 (CA)
Title: Zofenopril calcium
Inventor: GAIKWAD AVINASH C
IPC: A61K31/401
Filed: 2007-05-25
Abstract: The present invention relates to zofenopril calcium form (A) substantially free of other forms of zofenopril calcium and to zofenopril calcium having a chemical purity of more than 98.5%. The present invention also relates to methods of preparing such zofenopril calcium. It further relates to compositions comprising such zofenopril calcium. Zofenopril calcium, (4S)-l-[(2S)-3-benzoylthio-2-methylpropionyl]-4-(phenylthio)-L-proline calcium salt, has the following structure.
Patent CA-2654996-A1 (CA)
Title: Grill liner
Inventor: SARNOFF NORTON
IPC: A47J37/06
Filed: 2009-02-23
Abstract: In summary there is provided in one embodiment a grill liner for placement on top of a cooking grate and used to cook food placed thereon. The grill liner includes a plurality of holes to help allow heat to move through the grill liner. The grill liner further includes at least one flap that is secured to a portion of the grill liner through a frangible bridge, point, or line of weakness.  The frangible bridge when broken permits the flap to bend downwardly. The grill liner when placed on the cooking grate may then have its one or more flaps bent downwardly through bars such that the grill liner movement across the cooking grate can be limited.
Patent CA-2659296-A1 (CA)
Title: Cyclonic separator and a method of separating fluids
Inventor: SARSHAR MIR MAHMOOD
IPC: B04C3/00
Filed: 2007-07-19
Abstract: A cyclonic separator for separating fluids comprises an inlet chamber (6) having means for inducing fluids flowing through the chamber to swirl around an axis, a cyclonic separation chamber (10) connected to receive fluids from the inlet chamber, and an outlet chamber (8) connected to receive fluids from the cyclonic separation chamber. The outlet chamber (8) has a tangential outlet (22) for relatively dense fluids and an axial outlet (24) for less dense fluids. The separation chamber is elongate and has a length L and an inlet diameter D, where L/D is in the range 1 to 10.
Patent CA-2659688-A1 (CA)
Title: Hybrid wet electrostatic precipitator
Inventor: TRISCORI RONALD J
IPC: B03C3/017
Filed: 2009-03-23
Abstract: A hybrid, wet electrostatic precipitator has multiple precipitation zones for removing particulate and contaminants from a flue gas stream. A first precipitation zone has at least one discharge electrode and at least one collection plate made of a metal or a fiber glass reinforced plastic. A second precipitation zone has at least one discharge electrode and at least one collecting electrode which is a porous membrane sheet. The precipitation zones are in series with one another.
Patent CA-2659952-A1 (CA)
Title: 8-hydroxyquinoline compounds and methods thereof
Inventor: KHAFIZOVA GULNAZ
IPC: C07D215/16
Filed: 2007-08-23
Abstract: The present invention relates to 8-Hydroxyquinoline Compounds; compositions comprising an 8-Hydroxyquinoline Compound; and methods for treating or preventing a metalloproteinase-related disorder, such as, an arthritic disorder, osteoarthritis, malignant neoplasm, rheumatoid arthritis, asthma, chronic obstructive pulmonary disease, atherosclerosis, age-related macular degeneration, myocardial infarction, a corneal ulceration, an ocular surface disease, hepatitis, an aortic aneurysm, tendonitis, a central nervous system disorder, abnormal wound healing, angiogenesis, restenosis, cirrhosis, multiple sclerosis, glomerulonephritis, graft versus host disease, diabetes, an inflammatory bowel disease, shock, invertebral disc degeneration, stroke, osteopenia or a periodontal disease or comprising administering an effective dose of an 8-Hydroxyquinoline Compound to a mammal in need thereof.
Patent CA-2661960-A1 (CA)
Title: Noninvasive measurements of chemical substances
Inventor: ABREU MARCIO MARC
IPC: A61B3/12
Filed: 2001-08-20
Abstract: A contact device (2) placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like.
Patent CA-2663059-A1 (CA)
Title: Electronic device module comprising polyolefin copolymer
Inventor: MCGEE ROBERT L
IPC: H01L31/048
Filed: 2007-09-19
Abstract: An electronic device module comprising: A. At least one electronic device, e.g., a solar cell, and B. A polymeric material in intimate contact with at least one surface of the electronic device, the polymeric material comprising (1) a polyolefin copolymer with at least one of (a) a density of less than about 0.90 g/cc, (b) a 2% secant modulus of less than about 150 megaPascal (mPa) as measured by ASTM D-882-02), (c) a melt point of less than about 95C, (d) an .alpha.-olefin content of at least about 15 and less than about 50 wt% based on the weight of the polymer, (e) a Tg of less than about -35C, and (f) a SCBDI of at least about 50, (2) optionally, free radical initiator, e.g., a peroxide or azo compound, or a photoinitiator, e.g., benzophenone, and (3) optionally, a co-agent. Typically, the polyolefin copolymer is an ethylene/.alpha.-olefin copolymer. Optionally, the polymeric material can further comprise a vinyl silane and/or a scorch inhibitor, and the copolymer can remain uncrosslinked or be crosslinked.
Patent CA-2663493-A1 (CA)
Title: Device and method for compressing an edge of a building panel and a building panel with compressed edges
Inventor: JACOBSSON JAN
IPC: E04F15/02
Filed: 2007-09-13
Abstract: A device and method of producing a building panel with a compressed and c urved edge comprising a press tool, a heat device and a lubricating device a nd a building panel with a curved edge produced by the device and method.</S DOAB>
Patent CA-2664752-A1 (CA)
Inventor: AUER JOHANNES
IPC: A61K39/395
Filed: 2007-09-25
Abstract: An antibody binding to CCR5 characterized in that the heavy chain variable domain comprises an amino acid sequence of SEQ ID NO: 1, and has advantageous properties for the treatment of immunosuppressive diseases.
Patent CA-2665613-A1 (CA)
Inventor: HUSKOWSKA TERESA
IPC: C12N5/10
Filed: 2009-05-07
Abstract: A canola line designated SCV354718 is disclosed. The invention relates to the seeds of canola line SCV354718, to the plants of canola SCV354718, to plant parts of canola line SCV354718 and to methods for producing a canola plant produced by crossing canola line SCV354718 with itself or with another canola line. The invention also relates to methods for producing a canola plant containing in its genetic material one or more transgenes and to the transgenic canola plants and plant parts produced by those methods. This invention also relates to canola lines or breeding lines and plant parts derived from canola line SCV354718, to methods for producing other canola lines, lines or plant parts derived from canola line SCV354718 and to the canola plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid canola seeds, plants and plant parts produced by crossing the line SCV354718 with another canola line.
Patent CA-2665665-A1 (CA)
Title: Soil nail launcher
Inventor: RUCKMAN TIMOTHY ALLEN
IPC: E02D7/06
Filed: 2009-05-08
Abstract: A soil nail launching device and method are provided wherein the launching device includes an improved configuration for the protective shroud and an improved configuration for a connection between the breach and barrel of the launching device. For the protective shroud, a plurality of removable shroud plates are provided to ease maintenance of the shroud plate, as well as to provide more consistent pressure release after the launcher has been fired. The improved breach and barrel design includes a connection that does not reduce the area of the annular space that is evacuated during firing of the device, thereby optimizing the available volume of air to be transferred to the breach for launching the soil nail through the barrel.
Patent CA-2666538-A1 (CA)
Title: Utilisation de la citrulline pour le traitement des etats de denutrition
Inventor: WALRAND STEPHANE
IPC: A61K31/198
Filed: 2007-08-29
Abstract: La présente invention concerne l'utilisation de L-citralline (I) ou un se l pharmaceutiquement acceptable de celle-ci pour la préparation d'un médicam ent destiné au traitement des états de dénutrition liés à une diminution de la synthèse protéique dans le cadre de pathologies ne résultant pas d'une in suffisance intestinale. (I)
Patent CA-2669022-A1 (CA)
Inventor: LAGER BENGT
IPC: B02C18/16
Filed: 2006-11-07
Abstract: A shredding/recycling paper collection system and device (10), wherein a cabinet-style housing (20) with a self locking door (30) is adapted with a paper guard member (50) to prevent unauthorized reach-in access and assist with directional feed, and wherein the door- mounted paper guard member and the uniquely supported collection bag hangers (70) facilitate easy authorized access to collection bag (100) contents, while also providing secure positioning for weighty material within the housing.
Patent CA-2670022-A1 (CA)
Title: Homogeneous, intrinsic radiopaque embolic particles
Inventor: VAN HOOY-CORSTJENS CATHARINA SIBLLA JOSEPHINE
IPC: A61L31/18
Filed: 2007-10-31
Abstract: The invention is directed to embolic material comprising spherical, homogeneous and substantially non-porous radiopaque polymer particles based on at least one hydrophilic monomer and at least one radiopaque monomer according to general formula (I): wherein R is H, methyl or ethyl, and R1 is I, Br or formula (II): wherein R2 is O, NH, 0-[CH2-CH2-O]P-C(O)-, O- [CH2] m-O-C(O)-, O-[CH2]p-, NH-[CH2-CH2-O]p-C(O)-, NH-[CH2]m-O-C(O)- or NH-[CH2]p- wherein m>l and p>=l, R3 is I or Br and n is 1, 2 or 3, the iodine and/or bromine content being at least 5 wt.% based on the dry weight of the particle, the said particles having an average particle diameter of at least 10 µm and being able to imbibe water up to a volume increase of the particle of at least 10 %.
Patent CA-2670619-A1 (CA)
Title: Dissolution and processing of cellulose
Inventor: ADAMS SIMON
IPC: B29C48/32
Filed: 2007-11-22
Abstract: The invention relates to a method for dissolving the components of gel forming materials suitable for use in wound care comprising the steps of admixing said components with an ionic liquid. The ionic liquid may be selected from the group of tertiary amine N-oxides, N,N-dimethyl formamide/nitrogen tetroxide mixtures, dimethyl sulphoxide/paraformaldehyde mixtures and solutions of limium chloride in N,N-dimethyl acetamide or N-methyl pyrrolidone.
Patent CA-2671236-A1 (CA)
Inventor: DE TULLIO PASCAL
IPC: A61P25/00
Filed: 2009-07-03
Abstract: Composés de formule (I) : (voir formule I) dans laquelle : ~ RCy représente un groupement cycloalkyle ou un groupement cycloalkylalkyle non-substitué ou substitué, ~ R1, R2, R3 et R4, identiques ou différents, représentent chacun un atome d'hydrogène ou d'halogène ou un groupement nitro ; cyano ; hydroxy ; alkoxy ; alkyle ; amino non-substitué ou substitué ; carboxy ; alkoxycarbonyle ; aryloxycarbonyle ; aminocarbonyle non-substitué ou substitué.
Patent CA-2671240-A1 (CA)
Title: Hydraulic connection
Inventor: LUNDGREN BERTIL
IPC: F16L37/084
Filed: 2007-11-19
Abstract: Fixed connector part (10), adapted to constitute an end part of a hydraulic system of a work vehicle (1) and intended to be fixedly arranged on the work vehicle (1), the fixed connector part (10) comprising: at least two hydraulic couplings (14a-d); a first locking means (13, 16), which is intended to interact with a second locking means (23, 26) on a movable connector part (20), which constitutes an end part of a hydraulic system of a work equipment (2), wherein the first and second locking means are inter-connectable such that the hydraulic couplings of the fixed connector part (10) and the movable connector part (20), respectively, may be simultaneously interconnected through the interaction of the first and second locking means. Further each hydraulic coupling (14a-d) of the fixed connector part (10) comprises individual couplings, such that each hydraulic coupling (14a-d) of the fixed connector part (10) may be individually connected to a separate hydraulic coupling (24a-d). The invention also involves an arrangement including such a fixed connector part.
Patent CA-2676781-A1 (CA)
Inventor: OKAMOTO RIKI
IPC: B21B3/02
Filed: 2003-12-26
Abstract: The present invention provides a high-strength steel sheet excellent in hole-expandability and ductility. The steel sheet has a ferrite and martensite structure and a specific composition including C, Sl, Al, Mn, P, S, N, Mg, O, Ti and/or Nb with the balance consisting of iron and unavoidable impurities. The [%] of various elements in the steel satisfy the following formulas: [Mg%] >= ([O%]/1 6x0.8) x24 ... (1), [S%] <= ([Mg%]/24-[O%]/16x0.8+0.00012) x32 ... (2), [S%] <= 0.0075/[Mn%] ... (3), and -100 <= -300[C%]+105[Si%]-95[Mn%]+233[Al%] ... (8). The steel sheet structure contains not less than 80 % of crystal grains having a certain short diameter to long diameter ratio and not less than 80 % of ferrite crystal grains having a diameter of not less than 2 µm. The steel sheet has a strength exceeding 590 N/mm2 and contains a certain amount of composite precipitates of MgO, MgS and (Nb, Ti)N  of a certain size.
Patent CA-2679054-A1 (CA)
Title: Printed web and method for making
Inventor: OETJEN DAVID CHRISTOPHER
IPC: A61F13/15
Filed: 2008-02-19
Abstract: A web having printed thereon a colorant and/or a composition providing a skin health benefit. The web can be a three-dimensional, fluid pervious, polymeric web or a nonwoven web. The web can comprise a pattern of protrusions, a pattern of interconnecting members, the interconnecting members defining apertures. The apertures are defined in a first surface of the web in a first plane of the web, and extend in sidewall portions to a second surface in a second plane of the web. A colorant or lotion composition can be deposited on at least a portion of the second surface of the web.
Patent CA-2679549-A1 (CA)
Title: Dyes for keratinic fibers comprising anionic acrylic copolymers with mixed acid functionalities
Inventor: SCHMENGER JUERGEN
IPC: A61K8/81
Filed: 2008-02-20
Abstract: The invention relates to compositons for the oxidative or non-oxidative dyeing of keratin fibers, compositions for the simultaneously lightening and coloring of keratin fibers or compositions for the bleaching of keratin fibers, comprising an anionic acrylic thickener obtained by polymerization of (i) 5 to 95 molar percent of at least one monomer performing a weak acid function, and of (ii) 5 to 95 molar percent of at least one monomer performing a strong acid function, wherein such composition exhibits a fraction of water-soluble polymers ranging from 5 to 50 percent by weight of the total polymer, as well as the use of the above anionic acrylic thickener to thicken compositons for the oxidative or non-oxidative dyeing of keratin fibers, compositions for the simultaneously lightening and coloring of keratin fibers or compositions for the bleaching of keratin fibers.
Patent CA-2682212-A1 (CA)
Inventor: SMITH ERIC MICHAEL
IPC: A61K39/395
Filed: 2008-03-11
Abstract: Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
Patent CA-2682381-A1 (CA)
Inventor: PUIG SERRANO JORDI
IPC: C07D453/02
Filed: 2008-03-28
Abstract: The present invention provides an improved synthetic strategy for the preparation of solifenacin and pharmaceutically acceptable salts thereof.
Patent CA-2687186-A1 (CA)
Title: Protective garment with hybrid sleeve seam
Inventor: BEST MARGARET DIANE
IPC: A62B17/00
Filed: 2008-05-16
Abstract: A protective garment including a body portion having a front and a back, and a sleeve. The sleeve is coupled to the front of the body portion by a raglan seam and coupled to the back of the body portion by an inset seam.
Patent CA-2687232-A1 (CA)
Title: Remotely operated water bottom based drilling system using cable for auxiliary operations
Inventor: MCGINNIS TIMOTHY
IPC: E21B7/124
Filed: 2008-04-15
Abstract: A method for drilling formations below the bottom of a body of water includes disposing a drilling system on the bottom of the body of water. The formations are drilled by rotating a first drill rod having a first core barrel latched therein and advancing the drill rod longitudinally. At a selected longitudinal position, an upper end of the first drill rod is opened and a cable having a latching device at an end thereof is lowered into the first drill rod. The winch is retracted to retrieve the first core barrel. The first core barrel is laterally displaced from the first drill rod. A second core barrel is inserted into the first drill rod and latched therein. A second drill rod is affixed to the upper end of the first drill rod. Drilling the formation is then resumed by longitudinally advancing and rotating the first and second drill rods.
Patent CA-2689941-A1 (CA)
Inventor: BORRAS LEONARDO
IPC: A61K39/395
Filed: 2008-06-25
Abstract: The invention provides methods of using sequence based analysis and rational strategies to modify and improve the structural and biophysical properties of immunobinders, and in particular of single chain antibodies (scFvs), including such properties as stability, solubility, and/or antigen binding affinity. The invention provides methods of engineering immunobinders, and in particular scFvs, by performing one or more substitutions at amino acid positions identified by analysis of a database of selected, stable scFv sequences, wherein preferred amino acid residues for substitution have been identified. The invention also provides immunobinders prepared according to the engineering methods of the invention. The invention also provides preferred scFv framework scaffolds, into which CDR sequences can be inserted, as well as scFv antibodies made using these preferred framework scaffolds.     The invention provides methods of using sequence based analysis and rational strategies to modify and improve the structural and biophysical properties of immunobinders, and in particular of single chain antibodies (scFvs), including such properties as stability, solubility, and/or antigen binding affinity. The invention provides methods of engineering immunobinders, and in particular scFvs, by performing one or more substitutions at amino acid positions identified by analysis of a database of selected, stable scFv sequences, wherein preferred amino acid residues for substitution have been identified. The invention also provides immunobinders prepared according to the engineering methods of the invention. The invention also provides preferred scFv framework scaffolds, into which CDR sequences can be inserted, as well as scFv antibodies made using these preferred framework scaffolds.