baber/WOPTO huggingface dataset:
Patent EP-2550532-A4 (EP)
Title: Method of supressing cancer, increasing weight loss and/or increasing insulin sensitivity
Inventor: PESSIN JEFFREY E
IPC: A61K38/45
Filed: 2011-03-09
Abstract: The present invention provides methods for determining if an agent (i) treats or prevents cancer, (ii) treats or prevents obesity, and/or (iii) increases insulin sensitivity, comprising contacting Fyn and/or LKB1 with the agent and determining if the agent inhibits Fyn kinase activity or inhibits the interaction between Fyn and LKB1, wherein inhibition of Fyn kinase activity or inhibition of the interaction between Fyn and LKB1 by the agent indicates that the agent (i) treats or prevents cancer, (ii) treats or prevents obesity, and/or (iii) increases insulin sensitivity. The present invention also provides methods for treating cancer, treating obesity, or increasing insulin sensitivity in a subject, comprising administering to the subject a therapeutically effective amount of an agent that inhibits Fyn kinase or that inhibits the interaction between Fyn and LKB1.
Patent EP-2571375-A4 (EP)
Title: Bite sized refrigerated yogurt products
Inventor: PANNELL LISA K
IPC: A23C9/13
Filed: 2011-05-20
Abstract: Refrigerated yogurt products of small size suitable for eating with the fingers are prepared by providing a frozen yogurt composition in individual serving portions and coating the frozen yogurt portions with a fat based coating that is a solid at 45° F., thereby completely enveloping the frozen yogurt portions. The coated frozen yogurt portion is allowed to thaw to form a refrigerated yogurt product and is stored at a temperature of from about 32° F. to about 45° F. The yogurt composition has a final viscosity of from about 35,000 to about 150,000 cP at 4° C., and has a total solids content of at least about 22% and/or exhibits a viscosity reduction at 45° F. of less than 10% after two freeze/thaw cycles. Methods and products are described.
Patent EP-2582371-A4 (EP)
Title: Methods of treating or preventing estrogen-related diseases
Inventor: LABRIE FERNAND
IPC: A61P5/04
Filed: 2011-06-16
Abstract: Methods for treating or reducing the likelihood of acquiring estrogen-related (e.g. estrogen-exacerbated) diseases including endometriosis include administering to a patient a selective estrogen receptor modulator (SERM), in combination with inhibiting ovarian secretions, e.g., by administering an LHRH agonist or antagonist. In some embodiments, a precursor of sex steroids, said precursor being selected from the group consisting of dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), androst-5-ene-3&bgr;,17&bgr;-diol (5-diol), and androstenedione or a compound transformed into one of these, is also administered
Patent EP-2530964-A4 (EP)
Title: Method and device for terminal network locking
Inventor: WENG HAIYIN
IPC: H04W12/48
Filed: 2011-12-16
Abstract: Embodiments of the present invention provide a network locking method and apparatus for a terminal. The method mainly includes: utilizing an IMSI number carried on a SIM card of the terminal to register the SIM card with a network, and obtaining a PLMN number of the network; comparing a PLMN number segment of the network with a valid PLMN number segment pre-stored on the terminal, and allowing or limiting, according to a comparison result, use of the SIM card by the terminal. According to the embodiments of the present invention, the SIM card is registered with the network by utilizing the IMSI number carried on the SIM card and a data card is verified in the terminal and network combined verification manner, which may avoid a situation that a hacker sets a fake PLMN in a manner of a card sticker and the like to cheat SIM card verification, and ensure security of network locking for the terminal.
Patent EP-2551767-A4 (EP)
Title: Method and device for adjusting clock interrupt cycle
Inventor: YE YANZHONG
IPC: G06F9/48
Filed: 2011-10-09
Abstract: The present invention relates to a method and an apparatus for adjusting a period of clock interruption. The method comprises: determining a number of processes in a run-queue of a processor; and determining the period of clock interruption for use in a run state of the processor such that the period of clock interruption for use when the number of the processes is greater than a reference threshold is less than the period of clock interruption for use when the number of the processes is not greater than the reference threshold. The apparatus comprises a first determination block and a second determination block. With the method and apparatus according to the embodiment of the invention, it is possible to dynamically adjust the period of clock interruption such that the period of clock interruption for use in the run state of the processor can be changed according to needs with flexibility. When a shorter period of clock interruption is used for a relatively large number of processes, it is possible to increase the response speed. When a longer period of clock interruption is used for a relatively small number of processes, it is possible to reduce overhead and enable sufficient execution of processes. As a result, the processing efficiency of the system can be improved.
Patent EP-0056393-A4 (EP)
Title: Electric power supply system.
Inventor: MC SPARRAN LLOYD WILFRED
IPC: B60L50/12
Filed: 1981-06-22
Abstract: A multi-winding a-c electric power supply (12) is connected to a d-c load circuit (21p, 21n) via a power rectifier assembly (R) comprising at least two legs connected in parallel across the load circuit. Each leg has at least four serially interconnected unilaterally conducting devices (1, 4, l', 4'; 3, 6, 3', 6'). A first one (phase A) of the power supply windings is connected between the two rectifier legs at points between first (1, 3) and second (4, 6) devices thereof, and a duplicate (phase A') winding (voltages of both windings are in-phase and of equal amplitude) is connected between the legs at points between third (1', 3') and fourth (4', 6') devices thereof, whereby the windings are effectively connected in parallel. The respective junctures (D, E) of the second (4, 6) and third (1', 3') devices in all of the rectifier legs are interconnected by switching means (C1) which, upon switching to a closed circuit state, short circuits these junctures and thereby changes the connection of the windings from parallel to series.
Patent EP-0089982-A4 (EP)
Title: Play enclosure for children.
Inventor: LARKIN BRYAN JAMES
IPC: G06F15/80
Filed: 1982-10-05
Abstract: A play enclosure for a child, the play enclosure including two rings formed of pivotally connected links and a plurality of rods extending between the two rings.
Patent EP-0187854-A4 (EP)
Inventor: BAZZANO GAIL S
IPC: A61K8/67
Filed: 1985-07-15
Abstract: Nouveaux oxydes de pyrimidine substitués et leurs sels, ainsi que l'utilisation de ceux-ci en combinaison avec des rétinoïdes et/ou des analogues de la prostacycline afin d'accroître la vitesse de la croissance des cheveux et de prolonger la phase anagène du cycle des cheveux et de traiter certains types d'alopécies. Les nouveaux avantages inattendus à obtenir de l'utilisation de la présente invention sont: amélioration de la solubilité de la stabilité des composés actifs grâce à une augmentation de la dispersion de charge; prolongation de l'action des composés, excellente pénétration de la peau en raison de substituants lipophiles; compatibilité des composés avec des solvants non polaires utiles pour la préservation des groupes polaires lorsqu'ils sont en contact avec la peau et utiles pour l'encapsulage des composés dans un réseau polymère hydrophobe exempt de synérèse.
Patent EP-0301036-A4 (EP)
Title: Control system for a variable-reluctance motor, and method.
Inventor: GERBETZ ROBERT P
IPC: H02P25/08
Filed: 1987-10-07
Abstract: A control system (10) for a polyphase variable-reluctance motor synthesizes direct- and quadrature-axis currents (id, iq). The magnitude of the direct-axis current (id) is a function of the terminal voltage (Vt) and rotor speed. The magnitude of the quadrature-axis current (iq) is a function of rotor speed. Waveforms, the amplitudes of which reflect the magnitudes of id and iq, are first summed, and are then supplied to an inverter (20) which supplies appropriate currents (ia, ib, ic) to the motor windings (21A, 21B, 21C). In use, the improved control system performs a unique method of controlling the operation of such a motor by selectively controlling id and iq.
Patent EP-0349549-A4 (EP)
IPC: H01L23/48
Filed: 1987-12-30
Abstract: Une unité de support composite pour une puce de circuit intégré comprend un cadre de montage rigide (12) qui est fixé à une structure flexible relativement mince en forme de bande (14). Cette structure (14) est attaquée avec des languettes conductrices intérieures (16) et des languettes conductrices extérieures (24) selon une configuration telle que l'écartement entre les languettes conductrices est faible et la densité élevée, ce qui permet un raccourcissement des fils de connection (28) qui relient la puce de circuit intégré à l'unité de support. Il en résulte un accroissement significatif du nombre de conducteurs, lorsqu'on utilise un boîtier de circuit intégré de dimension standard.
Patent EP-0366721-A4 (EP)
Title: Improved process for making 90 k superconductors
IPC: C01G3/00
Filed: 1988-06-08
Abstract: There is disclosed an improved process for preparing a superconducting composition having the formula MBa2Cu3Ox wherein M is selected from the group consisting of Y, Nd, Sm, Eu, Gd, Dy, Ho, Er, Tm, Yb and Lu; x is from about 6.5 to about 7.0; said composition having a superconducting transition temperature of about 90 K; said process consisting essentially of heating a precursor powder in an oxygen-containing atmosphere at a temperature from about 875 DEG C to about 950 DEG C for a time sufficient to form MBa2Cu3Oy, where y is from about 6.0 to about 6.4; and maintaining the MBa2Cu3Oy in an oxygen-containing atmosphere while cooling for a time sufficient to obtain the desired product; said precursor powder being prepared by (a) mixing M2O3, Ba(OH)2.8H2O and CuO powders in an atomic ratio of M:Ba:Cu of about 1:2:3, or (b) forming an aqueous solution of M(NO3)3, Ba(NO3)2 and Cu(NO3)2 in an atomic ratio of M:Ba:Cu of about 1:2:3, adding to the resulting solution sufficient citric acid monohydrate to convert the metals present to their corresponding citrates, and spray drying the resulting solution to obtain the precursor powder.
Patent EP-0441877-A4 (EP)
IPC: B24D3/02
Filed: 1989-10-13
Abstract: Un article de fabrication, de préférence un insert de coupe du métal (10), a une composition céramique à base d'alumine consistant en (pourcentage en volume, v/o): 1,5 à 37,5 environ de barbes de carbure de silicium, 5 à 17,5 environ de zircone, le reste étant constitué par de l'oxyde de magnésium ajouté en quantité suffisante pour améliorer la durée de vie effective de coupe du métal du bord tranchant (70) de l'insert, et une matrice à base d'alumine ou d'oxyde d'aluminium dans laquelle les barbes de carbure de silicium, la zircone et le reste en oxyde de magnésium sont répartis sensiblement de manière homogène. Au moins 2 % en volume de la composition céramique à base d'alumine est de la zircone tétragonale.
Patent EP-0490923-A4 (EP)
Title: Diffraction grating and method of manufacture
IPC: B42D25/29
Filed: 1990-09-04
Abstract: A diffraction grating providing an optically variable image includes a pixellated diffraction grating in which each pixel is an individual optical diffraction grating so that the pixellated diffraction grating when illuminated generates an optically variable image. In another aspect the grating in some or all of the pixels of a diffracting grating formed by a regular matrix of pixels is arranged such that a reproduction of the grating by reflection contact printing generates a zero-order pattern which is grossly flawed by Moire or Talbot fringe effects. A method of forming the diffraction grating includes producing a counterpart pixellated diffraction grating of a substantially optically invariable image wherein each pixel of the optically invariable image is maped to a respective pixel of the pixellated diffraction grating. Each grating pixel is an individual optical diffraction grating of the associated pixel in the optically invariable image, so that the pixellated diffraction grating when illuminated generates an optically variable reproduction of the optically invariable image.
Patent EP-0585218-A4 (EP)
IPC: H01J21/10
Filed: 1991-02-22
Abstract: A novel vacuum tube type of electric apparatus preferably utilizes cold cathode emission to provide an electron source. A grid element (24) is employed to vary path direction for the particles, which are directed to alternative positions of an anode element (16). Secondary electron emission from a portion of the anode (36) is utilized to permit the anode potential to rise upon electron impingement, while a second portion of the anode (34) retains electrons to drive the anode potential in the negative sense. The structure allows both positive and negative states to be maintained, and has value in both rapid switching and memory application. The tube is advantageously manufactured on an insulating substrate which may be drawn to microscopic dimensions. This permits a dense pack to be accomplished, with low power requirements and high operating speed.
Patent EP-0527942-A4 (EP)
Title: Colonic drug delivery system
Inventor: SINTOV AMNON
IPC: C08B37/00
Filed: 1991-05-02
Abstract: A colonic delivery system for delivering a drug to the colon is provided. The system comprises a drug in combination with a matrix, wherein the matrix comprises a saccharide-containing polymer. According to the invention, the matrix is resistant to chemical and enzymatic degradation in the stomach and small intestine. The matrix is degraded in the colon by bacterial enzymatic action, and the drug is released. The system is useful for targeting drugs to the colon in order to treat colonic disease. The system is also useful for enteric administration of drugs such as proteins and peptides which are otherwise degraded in the stomach and small intestine.
Patent EP-0511380-A4 (EP)
IPC: A23L27/60
Filed: 1991-11-21
Abstract: On utilise des macrocolloïdes de polyhydroxyalcanoates en tant que succédanés de matières grasses. L'homopolymère préféré est le polyhydroxybutyrate. Les particules polymères peuvent avoir une granulométrie comprise entre 0,1 et 10 microns.
Patent EP-0605576-A4 (EP)
IPC: F02B25/04
Filed: 1992-09-23
Abstract: A two stroke internal combustion engine comprises a piston (8) reciprocating in compression chamber (6), an inlet valve (5) permitting the supply of scavenging air at high pressure to compression chamber (6), a small external combustion chamber (3) having restricted communication (9) with compression chamber (6), a valve (2) permitting the injection into combustion chamber (3) of a rich fuel/air mixture which in part passes to compression chamber (6) to form a fuel lean mixture with the scavenging air therein, and ignition means (1) to ignite the fuel which mixture in combustion chamber (3), in turn allowing burning fuel to ignite the fuel lean mixture in compression chamber (6) so that the operating temperatures in the compression chamber remain sufficiently low to inhibit the formation of nitrogen oxides therein.
Patent EP-0621983-A4 (EP)
Inventor: NATH PREM
IPC: H02S30/20
Filed: 1993-01-08
Abstract: Un système de toiture photovoltaïque comprend une pluralité de panneaux de toiture (20) sur chacun desquels se trouve un dispositif photovoltaïque (24), et comportant chacun un connecteur électrique (30, 32) pouvant être relié à un connecteur situé sur un autre panneau. Les panneaux comprennent des bords montants (26, 28) et une construction de toit à voliges et joints peut être facilement configurée par interconnexion des panneaux, fixation de ceux-ci sur le toit, et couverture des bords contigus au moyen des voliges.
Patent EP-0600094-A4 (EP)
Title: Apparatus for working on glass plate and the like.
Inventor: BANDO SHIGERU
IPC: B26D5/00
Filed: 1993-06-08
Abstract: An apparatus for working on a glass plate which can readily set, in association with the shape of a material glass, a position where a main cutting line is formed, a position where an auxiliary cutting line is formed, and a position for pushing, and which can perform quick working automatically. The working apparatus comprises: a snapping means (2); an input means capable of inputting various snapping data and instructions; a memory means for reading out data of shapes of intended glass plates, which are previously stored; a display means for displaying the above-described data of shapes, a shape of the material glass to be worked on, a position where an edge cutting line is formed, and a position for pressing; and a control means for controlling the operation of the snapping means (2).
Patent EP-0659735-A4 (EP)
Title: Process for producing aniline derivative.
Inventor: HIRAI KENJI - MINAMIDAI -CHOME
IPC: C07C217/84
Filed: 1993-09-10
Abstract: A process for producing an aniline derivative represented by general formula (3) by reacting a halogenated aminophenol derivative represented by general formula (1) or a carbonate derivative thereof with an alkylating agent of the formula (R-Y) in the presence of a phase-transfer catalyst in a bilayered system composed of an aqueous solution of an alkali metal hydroxide and an organic solvent, wherein R represents (substituted) C3-C12 cycloalkyl or C3-C6 alkynyl; or a process for producing an aniline derivative represented by general formula (3) by reacting an aminophenol derivative represented by general formula (1) with an alkylating agent in the presence of an alkali metal carbonate in an organic solvent. The process enables an intermediate for producing an oxazolidinedione derivative useful as the active ingredient of a herbicide to be efficiently produced without the necessity for protecting the amino group.
Patent EP-0681573-A4 (EP)
IPC: C07C311/06
Filed: 1994-01-28
Abstract: Taxane derivatives having alternative C2 substituent which is -OCOR31 wherein R31 is substituted phenyl and the substituent is selected from the group consisting of alkanoxy, protected hydroxy, halogen, alkyl, aryl, alkenyl, acyl, acyloxy, nitro, amino and amido.
Patent EP-0693883-A4 (EP)
Title: Fat substitute
Inventor: TARR BRYAN D
IPC: A23L1/0522
Filed: 1994-04-14
Abstract: The present invention provides a novel fat substitute composition, which is made from a defatted and mostly nondenatured proteinaceous particulate material, that, in a preferred embodiment, is derived from seed grains, and most preferably oats. In addition, a method of making and using the compositions to produce food products having a reduced caloric count, creamy texture and suitable mouth-feel, is disclosed. Further, a method to vary the viscosity of the resulting food products is disclosed, through changing the ratio of starch to protein in the fat substitute.
Patent EP-0745218-A4 (EP)
Inventor: BOETTCHER JEFFREY A
IPC: G01N21/64
Filed: 1995-02-08
Abstract: Un spectrophotomètre à fluorescence (100) mesure les caractéristiques de fluorescence de sondes fluorescentes dans des compositions fonctionnelles d'un échantillon. Le spectrophotomètre à fluorescence (100) émet une lumière qui permet l'excitation du ou des émetteurs de fluorescence contenus dans l'échantillon. L'émetteur de fluorescence excité émet dans un spectre de longueurs d'onde d'émission. Les émetteurs de fluorescence qui ont une plage de longueurs d'onde étroite avec un changement brutal d'intensité d'émission sont choisis pour servir de sonde fluorescente. Le spectrophotomètre à fluorescence (100) détecte le changement d'intensité sur cette plage étroite et réalise un calcul de dérivée sur la courbe d'intensité. Le spectrophotomètre à fluorescence (100) peut distinguer l'émetteur de fluorescence des autres émetteurs de fluorescence ou de fonds fluorescents créant des interférences.
Patent EP-0813423-A4 (EP)
Title: Composition to ameliorate osteolysis and metastasis
Inventor: MUNDY GREGORY R
IPC: A61K9/08
Filed: 1996-01-23
Abstract: A therapeutically effective amount of an antibody for a compound selected from the group consisting of PTHrp, TGFalpha, IL-1alpha, IL-1beta, IL-6, Lymphotoxin, TNF, PGE; 1,25 dihydroxy vitamin D<SUB>3 </SUB>and an antigenic fragment thereof used in the treatment of cancer metastasis to bone and cancer cell growth in bone as well as osteolysis and symptomatic sequelae thereof. An antibody immunoreactive with parathyroid hormone-related protein (PTHrp) is particularly preferred. Antibodies with human characteristics are included in the invention for application of the invention method to human subjects. Also, the antibody can be administered in an injectable is formulation in combination with a therapeutically effective amount of a bisphosphonate or pyrophosphate having the general structure formula wherein X is a linking moiety allowing for the interconnection of the phosphonate groups, and pharmaceutically acceptable salts, hydrates and partial hydrates thereof. The antibody and bisphosphonate act synergistically in the treatment of cancer metastases to bone and symptomatic sequelae thereof and particularly as regards bone resorption.
Patent EP-0955920-A4 (EP)
IPC: A61B18/14
Filed: 1996-01-24
Abstract: L'invention concerne des lames de ciseaux endoscopique bipolaire (26, 28) se présentant sous la forme d'une paire de lames métalliques électroconductrices comportant chacune un bord coupant (26a, 28a) et une surface de cisaillement adjacente (26f, 28f), au moins une des lames étant recouverte partiellement d'une matière céramique électro-isolante (29). La couverture partielle en céramique recouvre sensiblement la totalité du bord coupant de la lame ainsi qu'une partie relativement faible de sa surface de cisaillement adjacente au bord coupant. Si désiré, une partie angulaire plus grande (29b, 28f) de la surface de cisaillement peut être recouverte. La couverture en céramique est appliquée soit par masquage de la partie de la lame qui n'est pas à recouvrir et par pulvérisation de céramique sur la lame masquée, soit par liaison d'un élément en céramique mince à ladite lame. Dans un autre mode de réalisation de l'invention, une lame de ciseau (126, 128) est dotée d'une rainure à gorge (128g) recevant un insert sur une partie de sa surface de cisaillement adjacente à son bord coupant. Un insert en céramique (129) présentant une partie de languette (129c) au contact de la rainure est inséré dans la rainure à gorge (128g) et forme un bord coupant en céramique sur la lame métallique. L'invention concerne également un instrument (10) de type ciseaux de cautérisation bipolaire endoscopique utilisant les lames partiellement recouvertes de l'invention.
Patent EP-0871762-A4 (EP)
Inventor: FRENCH CYNTHIA K
IPC: C07K14/47
Filed: 1996-04-11
Abstract: L'invention concerne un auto-antigène HP-8 qui est lié au lupus érythémateux systémique. L'antigène HP-8 est exprimé par un gène qui a été identifié par des tests de sélection immunologiques préliminaires en utilisant une bibliothèque d'expression GT11 des ADN complémentaires du placenta humain et l'anticorps monoclonal 3E10. L'anticorps 3E10 est un anticorps anti-ADN double hélice à faible affinité dérivé de modèles murins MRL du lupus érythémateux systémique.
Patent EP-0876387-A4 (EP)
Title: Method to improve the biological and antiviral activity of protease inhibitors
Inventor: SCHINAZI RAYMOND F
IPC: A61P31/04
Filed: 1996-08-30
Abstract: Methods for improving the cellular uptake of protease inhibitors (e.g., HIV protease inhibitor), alone or in the presence of one or more additional therapeutic agents, in protease inhibitor-based therapies, involving administration of one or more AAG-binding compounds, such as macrolide or lincosamide antibiotics, which have sufficient binding affinity for AAG to competitively bind AAG in the presence of the protease inhibitor.