baber/WOPTO huggingface dataset:
Patent NZ-572155-A (NZ)
Title: Use of deferasirox for treating iron overload resulting from hereditary haemochromatosis
Inventor: NICK HANSPETER
IPC: A61P43/00
Filed: 2007-05-21
Abstract: Disclosed is the use of 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid (Formula I) in the manufacture of a medicament for the treatment of hereditary hemochromatosis wherein the treatment of hereditary hemochromatosis comprises: (a) an induction phase wherein the medicament comprising the compound of Formula I is adapted for administration at a daily dose of 5-20 mg/kg of body weight with or without phlebotomy, followed by (b) a maintenance phase wherein the medicament comprising the compound of Formula I is adapted for administration at a daily dose of 1 to 5 mg/kg of body weight.
Patent NZ-574018-A (NZ)
Title: Clostridial vaccine comprising levamisole
Inventor: LEECH WAYNE FREDERICK
IPC: A61K31/4188
Filed: 2008-12-24
Abstract: Disclosed is a composition including at least 8%w/v levamisole base (which may be present in the form of levamlsole phosphate) and a clostridial vaccine. Also disclosed is a method of treating non-human animals (such as ruminants), characterised by the step of administering to the non-human animal the above composition.
Patent NZ-579957-A (NZ)
Title: Food comprising at least 30 mass percent alkalized cocoa shells and method therefor
Inventor: CHRONOPOULOS DIMITRIOS
IPC: A23L29/206
Filed: 2009-09-25
Abstract: Disclosed is a food comprising at least 30 mass percent alkalised cocoa shells based on the total mass of alkalised cocoa shells and cocoa powder in the food.
Patent NZ-582293-A (NZ)
Title: Method for treating a food, feed or agricultural product with natamycin composition
Inventor: HEE VAN PIM
IPC: A23L13/00
Filed: 2008-07-17
Abstract: Disclosed is an aqueous antifungal composition comprising natamycin in an amount of from 50 to 400,000 ppm, xanthan gum in an amount of from 0.02% to 10% (w/w) , citric acid in an amount of from 0.05% to 5% (w/w) and lactate in an amount of from 0.05% to 7.5% (w/w) , said composition being free of chloride salts, wherein the composition may further comprise at least one compound selected from the group consisting of additional antimicrobial compounds, flow agents, surfactants and buffering agents. Said composition is stable after storage for at least 12 weeks at a temperature of 20 Deg. C; and it is suitable for the treatment of a food such as a cheese or a sausage product, feed or agricultural product for the prevention of mould growth, fungal growth and yeast growth, and it is also suitable for preventing corrosion of process equipment used during the treatment of food, feed or agricultural products with an aqueous antifungal composition.
Patent NZ-587145-A (NZ)
Title: Adhesive agent for application on a sanitary object
Inventor: LEIPOLD JOACHIM
IPC: C11D1/00
Filed: 2009-02-09
Abstract: Disclosed is an agent, where the agent comprises fillers from the group of surfactants and also an adhesion promoter, characterized in that the adhesion promoter is selected from the group of polyalkylene derivatives which comprise polyalkylene chains with randomly distributed functional groups, or from the group of copolymers from the group of monoalkylesters of poly/methyl vinylethers/carboxylic anhydrides, olefin homopolymers and copolymers of two or more olefins being partially oxidized or further functionalized via graft molecules, and from the group of polyalkyleneimines, also in alkoxylated form, polyether amines (alkoxylated amines) and polyglycerol polyether alkylcarboxylic acids or polymers or derivatives containing these polymer, wherein the concentration of the surfactants in the case of an adhesion promoter from the group of polyalkyleneimines is between 7 and 60 percent by weight.
Patent NZ-591617-A (NZ)
Title: Liquid chromatography-mass spectrometer and its uses for the selective identification of immunogenic epitopes
Inventor: VAN ELS CECILE ANTOINETTE CAROLA MARIA
IPC: C07K16/00
Filed: 2009-09-09
Abstract: A liquid chromatography-mass spectrometer device for analysing a sample comprising a pump arrangement, an analytical column, an electro spray ionization unit and a mass spectrometer, wherein the pump arrangement is constructed and arranged for providing a nanoscale flow to the analytical column, wherein the analytical column comprises a stationary phase for liquid chromatography and wherein the analytical column has an interior diameter of less than 200 microns, wherein the electro spray ionization unit comprises an emitter for electro spraying positioned downstream of the analytical column in the flow path of the sample, said emitter having an interior diameter of less than 70 microns, wherein the mass spectrometer is positioned downstream of the emitter, the liquid chromatography-mass spectrometer device comprising at least two-dimensional chromatography, wherein the first dimension comprises at least strong cation exchange (SCX) and the second dimension comprises reversed phase chromatography, wherein an elution solvent is a salt-free solution for both the first and second dimension of the two-dimensional chromatography.
Patent NZ-592906-A (NZ)
Title: Process for the preparation of piperazine compounds and hydrochloride salts thereof
Inventor: CZIBULA LASZLO
IPC: C07D295/135
Filed: 2009-12-18
Abstract: Disclosed is a process for the preparation of compounds of general formula (I) and hydrochloric acid salts and/or hydrates and/or solvates thereof, wherein the substituents are as described within the specification, characterised in that dissolving or suspending trans 4-{ 2-[4-(2,3-dichlorophenyl)-piperazine-1-il]-ethyl} -cyclohexylamine of formula (III) or a salt or a hydrate or a solvate thereof in an inert solvent in the presence of a base then adding a carbonic acid derivative of general formula (VI), wherein the substituents are as described within the specification, and reacting the compound of general formula (IV) obtained in situ or, optionally in isolated state with an amine of general formula (V), to obtain the compound of general formula (I).
Patent NZ-599009-A (NZ)
Title: Coating compositions and methods for using the same as a spot blender
Inventor: BOWMAN MARK P
IPC: B05D5/00
Filed: 2010-10-26
Abstract: 599009 Disclosed is a composition comprising: 2 to 10% of a polymeric polyol; 1 to 5% of a urethane (meth)acrylate; less than 0.1% by weight of a photoinitiator; and 90 to 97% of solvent; the percentages being by weight and based on total weight of the composition. Also disclosed is a coating system comprising the composition and a method for repairing a damaged spot on an automobile comprising applying the composition or coating system.
Patent NZ-599950-A (NZ)
Title: Improvements in and relating to pipe fittings
Inventor: ALLOWAY STEPHEN GEORGE
IPC: F16L41/04
Filed: 2012-05-11
Abstract: 599950 A pipe fitting (1) is disclosed including a body (2) having a threaded end (3) and a retaining portion (4, 9. A compression fitting (7) is configured to engage with the threaded end (3) of the body. A tubular seal (6) is configured to fit around the body between the retaining portion and the threaded end and a compression end washer (8) is configured to interface between the compression fitting and a surface on the tubular seal. The tubular seal (6) is formed from a deformable material which bulges when subjected to compression along the length of the tubular seal. The retaining portion (4, 9) is configured to bias the first end of the seal (12b) towards the body (2) when subject to compression.
Patent NZ-600172-A (NZ)
Title: Process for preparing modulators of cystic fibrosis transmembrane conductance regulator
Inventor: AMBHAIKAR NARENDRA BHALCHANDRA
IPC: C07D487/08
Filed: 2010-10-21
Abstract: Disclosed herein is a process for producing the hydrochloride salt of Compound 1 having solid Form A-HCl comprising: (a) reacting Compound 2 with the hydrochloride salt of Formula 3 (3-HCl) in the presence of a coupling agent, a base, and a polar aprotic solvent; wherein the coupling agent is selected from the group consisting of 2-chloro-1,3-dimethyl-2-imidazolium tetrafluoroborate, 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate (HBTU), 2-chloro-4,6-dimethoxy-1,3,5-triazine, 1-H-benzotriazolium-1-[bis(dimethyl amino)methylene]-5-chlorohexafluorophosphate (HCTU), 2-(1H-7-Azabenzotriazol-1-yl)-1,1,3,3-tetramethyl uronium hexafluorophosphate (RA TU), 1-hydroxybenzotriazole (HOBT)/ 1-(3-(dimethylamino)propyl)-3-ethyl-carbodiimide hydrochloride (EDCl), and propane phosphonic anhydride; wherein the base is selected from the group consisting of K2CO3, Et3N, N-methylmorpholine (NMM), pyridine, and diisopropylethyl amine (DIEA); and wherein the polar aprotic solvent is selected from the group consisting of ethyl acetate, isopropyl acetate, tetrahydrofuran, methylethyl ketone, N-Methyl-2-pyrrolidone, acetonitrile, N,N-dimethyl formamide, and 2- methyltetrahydrofuran; and (b) treating a mixture comprising the product of step (a) with HCl; wherein step (a) is performed at a reaction temperature that is maintained between 15°C and 70°C.
Patent NZ-600593-A (NZ)
Title: Novel (heterocycle/condensed piperidine)-(piperazinyl)-1-alkanone or (heterocycle/condensed pyrrolidine)-(piperazinyl)-1-alkanone derivatives and use thereof as p75 inhibitors
Inventor: BONO FRANCOISE
IPC: C07D513/04
Filed: 2010-12-13
Abstract: The disclosure relates to (heterocycle/condensed piperidine)-(piperazinyl)-1-alkanone or (heterocycle/condensed pyrrolidine)-(piperazinyl)-1-alkanone derivatives of the general formula (I), where A, W, n, and R2 are as defined in claim 1. The disclosure moreover relates to the method for preparing said derivatives and to the therapeutic use of said derivatives. Compounds of the disclosure include: 2-[8-(5-fluoropyrimidin-2-yl)-3,8-diazabicyclo[3.2.1]oct-3-yl]-1-[2-(5-trifluoromethylpyridin-2-yl)-2,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl]ethanone; 6-{ 3-[2-oxo-2-(1-phenyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl)ethyl]-3,8-diazabicyclo[3.2.1]oct-8-yl} nicotinic acid; 6-{ (2R,5S)-2,5-dimethyl-4-[2-oxo-2-(2-phenyl-6,7-dihydro-4Hthiazolo[5,4-c]pyridine-5-yl)ethyl]piperazin-1-yl} nicotinonitrile and 1-(2-methyl-2,4,6,7 -tetrahydropyrazolo[4,3-c]pyridin-5-yl)-2-[8-(5-trifluoromethylpyridin-2-yl)-3,8-diazabicyclo[3.2.1]oct-3-yl]ethanone.
Patent NZ-601152-A (NZ)
Title: Topical sunscreen compositions
Inventor: SINGLETON LAURA C
IPC: A61K8/25
Filed: 2011-07-13
Abstract: The disclosure relates to sunscreen compositions designed for application to wet skin, comprising an organic UV-filter which may be selected from the group consisting of octocrylene, a benzotriazole, anisotriazine, an ester of salicylic acid, an ester of cinnamic acid and a derivative of a benzoylmethane, a water-insoluble, low-volatility C2-C8 liquid silicone selected from either ethyl methicone and caprylyl methicone, a branched fatty acid ester of a polyprotic carboxylic acid and a film forming polymer, all in a volatile solvent. The branched fatty acid ester of a polyprotic carboxylic acid and the water-insoluble, low-volatility C2-C8 liquid silicone are present in a ratio from about 3:1 to 4.25:1. The compositions may further contain a wax or aerosol component.
Patent NZ-602422-A (NZ)
Title: Mixing apparatus and a tanker incorporating it
Inventor: DINGLE WAYNE DENIS
IPC: B01F23/00
Filed: 2011-03-11
Abstract: 602422 Mixing apparatus for mixing a powdered animal feed substance in a liquid. The apparatus has a tank 20 and a pump 23. A dispersing means 37, 38 is located within the tank 20 and has a plurality of outlets 40, 41 which are arranged so that when, in use, liquid is within the tank, the outlets are above the surface of the liquid in the tank and are orientated such that they are directed toward the surface. The pump 23 is connected to an inlet 36 and an outlet 26 of the tank 20. The dispersing means 37, 38 is coupled to the inlet 36. The pump 23 creates a flow of liquid (and any powdered feed substance mixed therein) through the plurality of outlets 40, 41 to the surface of the liquid to thereby create a turbulence in the liquid in the tank to facilitate mixing of the powdered feed substance and the liquid.
Patent NZ-603246-A (NZ)
Title: A method for estimating electricity consumption cost based on data received from an electricity meter
Inventor: DENG PAUL PENG
IPC: G06F17/40
Filed: 2012-10-25
Abstract: 603246 Disclosed is a device for estimating electricity consumption cost of electrical appliances in standby mode. The device includes a database for storing electricity consumption data at time intervals, and a processor. The processor is configured to retrieve electricity consumption data for a plurality of time intervals having the lowest values from a predetermined total number of time intervals for a single day. The processor is configured to then calculate a daily energy usage of electrical appliances in standby mode by calculating an average energy usage value for the plurality of time intervals having the lowest values in a single day. This average is then multiplied by the predetermined total number of time intervals for the single day. The processor is configured to perform this calculation for each of a predetermined number of previous days and to calculate an average daily energy usage of electrical appliances in standby mode by averaging the calculated daily energy usage of electrical appliances in standby mode for the predetermined number of previous days. This standby data can be used to estimate a component of an electricity bill that is due to standby usage and present this to a user on a display of the device.
Patent NZ-610566-A (NZ)
Title: Antibody purification
Inventor: WAN MIN W
IPC: A61K39/395
Filed: 2007-04-04
Abstract: Disclosed is a pharmaceutical composition comprising an isolated human anti-TNFalpha antibody, or an antigen-binding portion thereof, and a pharmaceutically acceptable carrier, wherein the anti-TNFalpha antibody, or antigen-binding portion thereof, comprises a light chain variable region comprising a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 3 or an amino acid sequence differing from SEQ ID NO: 3 by a single alanine substitution at position 1, 4, 5, 7 or 8, a light chain CDR 2 comprising the amino acid sequence of SEQ ID NO: 5, and a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 7; and a heavy chain variable region comprising a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 4 or an amino acid sequence differing from SEQ ID NO: 4 by a single alanine substitution at position 2, 3, 4, 5, 6, 8, 9, 10 or 11, a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 6, and a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 8, wherein the composition is characterised in that when the composition is assayed in a cathepsin L kinetic assay, a level of cathepsin L activity less than 1.84 RFU/s/mg of antibody is observed, and wherein the cathepsin L kinetic assay comprises: i) diluting the composition in a polystyrene container in a solution containing 25 mM NaOAc, 5 mM DTT and 1 mM EDTA at pH 5.5, ii) adding dextran sulfate to a concentration of 0.035 μg/mL and incubating at 37 degrees Celsius for six hours, iii) adding Z-leucine-arginine covalently bound at its C-terminus to a fluorescent 7-amino-4-methyl coumarin (Z-leucine-arginine-AMC), wherein the diluting, adding, and incubating steps are sufficient to permit the measurement of cathepsin L hydrolysis of the Z-leucine-arginine-AMC within a linear range, and iv) measuring Z-leucine-arginine-AMC hydrolysis in the linear range in RFU/s/mg of antibody, wherein the sequences are as defined in the complete specification.
Patent NZ-611967-A (NZ)
Title: Deformed shank fastener
Inventor: VERSINO ANTHONY M
IPC: F16B15/06
Filed: 2009-04-16
Abstract: A nail which includes a head, a penetrating tip, a shank extending from the head to the penetrating tip and having a circumference and a longitudinal axis, and a number of spiral pattern rows of deformations in the shank extending outwardly of the shank. The rows configured to impart a rotating motion to the nail as the nail is driven into a substrate. The deformations include a lead angle of about 50 degrees defined at a base of the deformation and the shank. The deformations have an inwardly tapered leading end and an interference face trailing end to provide a resistance to withdrawal of the nail after being driven into the substrate. The deformations in each row are substantially contiguous with adjacent deformations in the same row. Each of the deformations defines a cross-sectional footprint shape where a base of the deformation meets the shank. The footprint shape includes a portion that is tapered along the path of the spiral in a direction of the penetrating tip.
Patent NZ-613157-A (NZ)
Title: A dowel for a crumbly supporting material
Inventor: BULLET MARTINE
IPC: F16B13/12
Filed: 2012-01-06
Abstract: A dowel or anchor sleeve for a crumbly supporting material is disclosed. The dowel is made from a die stamped metal sheet blank that is rolled to produce a cylinder. The dowel includes an abutment collar (1) at one end and has an expandable tubular body (3). The body has expanding means (10) arranged for receiving fastener that expands the body to anchor the dowel in the supporting material. After the blank has been rolled it forms a threaded portion (11). The cylinder is indexed with a tenon (33) and mortise joint to ensuring the threaded portions (11) align.
Patent NZ-616136-A (NZ)
Title: Maleate salts of (e)-n-{ 4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl} -4-(dimethylamino)-2-butenamide and crystalline forms thereof
Inventor: LU QINGHONG
IPC: C07D401/12
Filed: 2008-10-16
Abstract: Disclosed herein are maleate salt forms of (E)-N-{ 4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl} -4-(dimethylamino)-2-butenamide, (NERATINIB) methods of preparing crystalline maleate salt forms, the associated compounds, such as its degradation and impurities and pharmaceutical compositions containing the same. The maleate salts are useful in treating cancers, particularly those affected by kinases of the epidermal growth factor receptor family.
Patent NZ-617520-A (NZ)
Title: Drug selection for breast cancer therapy using antibody-based arrays
Inventor: SINGH SHARAT
IPC: G01N33/53
Filed: 2009-02-24
Abstract: Disclosed is a method comprising A) incubating cells from a breast tumor with an anticancer drug in vitro and lysing the incubated cells to produce a cellular extract, B) detecting the activation state of one or more analytes in the cellular extract and C) determining whether the anticancer drug is suitable or unsuitable for the treatment of breast tumor, wherein the method is for selecting a suitable anticancer drug, identifying the response of a breast tumor or predicting the likelihood that a subject will respond.
Patent NZ-621912-A (NZ)
Title: Powdered nutritional formulations including spray-dried plant protein
Inventor: NEAL CYNTHIA S
IPC: A23L33/00
Filed: 2012-09-20
Abstract: The disclosure relates to a powdered nutritional formulation comprising a dryblended plant protein, wherein at least a portion of the dryblended plant protein is spray-dried plant protein. The plant protein may be pea protein or soy protein and the formulation may further comprise a milk protein. The disclosure also relates to a method of producing the powdered nutritional formulation.
Patent NZ-625896-A (NZ)
Title: 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-yl)picolinamide derivatives as orexin receptor antagonists
Inventor: BOLLI MARTIN
IPC: C07D417/14
Filed: 2012-11-07
Abstract: Provided are 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2- yl)picolinamide derivative compounds of Formula (I), wherein the variables are as defined in the specification. Examples of the compounds include [(R)-3-(2-Fluoro-5-[1,2,3]triazol-2-yl-benzyl)-morpholin-4-yl]-(5-methyl-2-[1,2,3]triazol-2-yl-phenyl)-methanone and [(R)-3-(4-Methyl-3-pyrimidin-2-yl-benzyl)-morpholin-4-yl]-(2-[1,2,3]triazol-2-yl-phenyl)-methanone. The compounds are orexin receptor antagonists. The compounds may be useful in the treatment of anxiety disorders, addiction disorders, mood disorders, appetite disorders, cognitive dysfunctions and sleep disorders.
Patent NZ-628828-A (NZ)
Title: Pharmaceutical composition for the prevention or treatment of non-alcoholic fatty liver disease
Inventor: KWON SE CHANG
IPC: A61P1/16
Filed: 2013-03-08
Abstract: The disclosure relates to a pharmaceutical composition for the prevention or treatment of non-alcoholic fatty liver disease comprising an insulinotropic peptide drug conjugate prepared by covalently linking an insulinotropic peptide and an immunoglobulin Fc region via a non-peptidyl polymer as an active ingredient, wherein the insulinotropic peptide is selected from the group consisting of exendin-4 or exendin-4 derivatives. The non-peptidyl polymer is selected from the group consisting of polyethylene glycol, polypropylene glycol, copolymers of ethylene glycol-propylene glycol, polyoxyethylated polyols, polyvinyl alcohol, polysaccharides, dextran, polyvinyl ethyl ether, biodegradable polymers, lipid polymers, chitins, hyaluronic acid, and combinations thereof.
Patent NZ-700830-A (NZ)
Title: A fluid dispenser
Inventor: PAUL FLEMING BUCKLEY
IPC: A61M35/00
Filed: 2014-09-12
Abstract: Disclosed is a fluid dispenser, integrated into one hand piece (1). The fluid dispenser comprises a variable volume chamber, a plunger (8), a power source (5), a motor (3), a trigger (2) and a controller (6). The plunger translates in a linear direction relative to the chamber along a common longitudinal axis. The plunger acts to draw a volume of fluid into the chamber via a chamber inlet (13) and/or expel the fluid from the chamber via a chamber outlet (14). The power source and motor drive the translational movement of the plunger thereby causing a change in the volume of the chamber resulting in drawing or expelling fluid into or from the chamber. The trigger, when activated causes fluid to be expelled from the chamber. The controller is operatively linked to the plunger and chamber, wherein the controller acts to control the volume expelled from the chamber by varying plunger a subsequent plunger position after the trigger is engaged.
Patent NZ-702747-A (NZ)
Title: Substituted tricyclic compounds as fgfr inhibitors
Inventor: WU LIANGXING
IPC: C07D498/14
Filed: 2013-06-12
Abstract: The present invention relates to tricyclic compounds of formula I, and pharmaceutical compositions of the same, that are inhibitors of one or more FGFR enzymes and are useful in the treatment of FGFR- associated diseases such as cancer.
Patent NZ-703885-A (NZ)
Title: An application chat server
Inventor: WALKER MICHAEL
IPC: H04L12/58
Filed: 2013-06-14
Abstract: An application chat server associated with a first access device and a second access device, wherein the first access device and the second access device are associated with a first statement of task capability and a second statement of task capability, respectively. The application chat server further adapted to analyse, based upon one or more of the first and second statements of task capability, a task command to determine that the second access device is capable of executing at least one task and generating, in response to the determining, an execution command, wherein the execution command associated with the at least task and transmitting an execution signal, wherein the execution signal associated with the execution command.