baber/WOPTO huggingface dataset:
Patent CA-2589521-C (CA)
Inventor: ZAKNOEN SARA
IPC: A61K33/243
Filed: 2005-12-13
Granted: 2014-04-01
Abstract: A combination therapy for treating patients suffering from proliferative diseases or diseases associated with persistent angiogenesis is disclosed. The patient is treated with a camptothecin derivative and one or more chemotherapeutic agents selected from a microtubule active agent; an alkylating agent; an anti-neoplastic anti-metabolite; a platin compound; a topoisomerase II inhibitor; a VEGF inhibitor; a tyrosine kinase inhibitor; an EGFR kinase inhibitor; an mTOR kinase inhibitor; an insulin-like growth factor I inhibitor; a Raf kinase inhibitor; a monoclonal antibody; a proteasome inhibitor; a HDAC inhibitor; and ionizing radiation.
Patent CA-2592806-C (CA)
Title: Personal snow vehicle
Inventor: SADAKUNI NAOKI
IPC: B62B17/04
Filed: 2007-06-26
Granted: 2013-04-30
Abstract: A straddle-type personal snow vehicle includes a body frame, an engine, a front support and a rear track drive mechanism that is driven by the engine. The front support may be a front suspension that supports at least one front ski. The rear track drive mechanism may be supported by a rear suspension that may include multiple linkage members. In one arrangement, the track drive mechanism includes a drive wheel and at least a first support wheel. An axis of rotation of the first support wheel is positioned forward of an axis of rotation of the drive wheel. In one arrangement, the at least one front ski is coupled to the front suspension by a tool-less attachment mechanism.
Patent CA-2596385-C (CA)
Inventor: DREVET HELENE
IPC: H01G11/26
Filed: 2006-01-30
Granted: 2014-04-08
Abstract: The invention concerns a method for making a porous substrate-electrode complex (6) with load rate not less than 80 % for a supercapacitor including at least the following steps: preparing a mixture containing at least one polymer (1), at least one liquid pore-forming platicizer (3), and at least one active filler (2); extruding the mixture in paste form; depositing the paste on the substrate and laminating same; and treating the resulting complex to eliminate all or part of the plasticizer (3) and generate porosity in the electrode. The invention also concerns an electrode paste and a collector-electrode complex.
Patent CA-2601163-C (CA)
Inventor: BEUKEVELD GERHARDUS JOHANNES JOZEF
IPC: B09C1/10
Filed: 2006-03-10
Granted: 2014-01-07
Abstract: The invention provides methods for in situ acceleration of biological degradation of chlorinated hydrocarbons in a soil. The invention particularly provides a method for in situ acceleration of biological degradation of chlorinated hydrocarbons in a soil comprising adding H2, CO2 and acetate.
Patent CA-2607148-C (CA)
Title: Valves, devices, and methods for endobronchial therapy
Inventor: CECKA WALTER
IPC: A61M16/20
Filed: 2006-05-18
Granted: 2014-12-23
Abstract: Various valves, adapters, ventilator circuits, and methods are disclosed. In one or more embodiments, a valve includes a support that includes a plurality of apertures. The support includes a center and an outer edge. The plurality of flaps includes a flap for each aperture. Each flap has an end connected proximal to the center of the support. Each flap is capable of moving between a closed position and an opened position.
Patent CA-2608457-C (CA)
Inventor: YOSHIDA ATSUSHI
IPC: A61K9/48
Filed: 2006-05-17
Granted: 2013-09-10
Abstract: An object of the present invention is to provide a new medicinal use of 2-phenyl-1,2-benzisoselenazol-3 (2H) -one or a salt thereof. 2 -Phenyl-1, 2 -benzisoselenazol-3 (2H) -one or a salt thereof exhibits an excellent prevention and improvement effect in corneal disorder models, and. is therefore useful as a preventive or therapeutic agent for a keratoconjunctival disorder such as dry eye, superficial punctate keratopathy, corneal epithelial defects, corneal erosion, corneal ulcer, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis or conjunctivitis.
Patent CA-2611094-C (CA)
Title: Air spring assembly and method
Inventor: TAYLOR ROBERT
IPC: F16F9/04
Filed: 2006-05-05
Granted: 2011-03-22
Abstract: An air spring assembly (100) including a first end member (102) that includes a side wall (122), and a second end member (104) spaced from the first end member. A flexible sleeve (106) includes a sleeve wall (132) and opposing open ends (134, 136) secured on the first and second end members. First and second retaining member (110 and 112 or 114 and 116) are used to secure one open end of the flexible sleeve on the associated end member. A method (200) is also disclosed.
Patent CA-2619443-C (CA)
Title: Glypican-3 (gpc3)-derived tumor rejection antigenic peptides useful for hla-a2-positive patients and pharmaceutical comprising the same
Inventor: NISHIMURA YASUHARU
IPC: C12N5/0784
Filed: 2006-08-08
Granted: 2014-07-08
Abstract: It is an object of the present invention to identify a glypican-3 -derived peptide which can bind to HLA-A2 and activate human killer T cells, so as to provide a means for carrying out an immunotherapy which is able to target approximately 40% of Japanese patients suffering from several types of cancers, which express GPC3 at a high level. The present invention provides a peptide of any of the following (A) or (B): (A) a peptide, which has the amino acid sequence as shown in any one of SEQ ID  NOS: 1 to 3; or (B) a peptide, which has an amino acid sequence comprising a substitution or addition of one or two amino acids with respect to the amino acid sequence as shown in any one of SEQ  ID NOS: 1 to 3, and which has ability to induce killer T cells.
Patent CA-2623107-C (CA)
Title: Vehicle body frame structure
Inventor: YAMASHITA AKIHIRO
IPC: B62K5/01
Filed: 2008-02-29
Granted: 2010-08-17
Abstract: To divide a frame structure body, including a suspension supporting section in a vehicle body frame structure of a vehicle having paired right and left wheels, into a small number of relatively compact frame components, and to reduce the number of steps needed to manufacture a frame. A vehicle body frame structure includes, in a front frame assy, a front suspension supporting section having paired right and left cushion top end supporting parts, paired right and left upper arm supporting parts, paired right and left upper arm supporting parts, paired right and left lower arm supporting parts, and paired right and left lower arm supporting parts. In the vehicle body frame structure, the front frame assy has a configuration which is vertically bisected chiefly into an upper front frame and a lower front frame. The upper front frame includes the right and left cushion top end supporting parts. The lower front frame includes the right and left upper arm supporting parts, the right and left upper arm supporting parts, the right and left lower arm supporting parts, and the right and left lower arm supporting parts.
Patent CA-2623165-C (CA)
Inventor: STOCK DAVID
IPC: A01N43/54
Filed: 2006-09-27
Granted: 2012-12-11
Abstract: A fungicidal composition in the form of a liquid concentrate, which, in addition to at least one formulation adjuvant, comprises cyprodinil and an unsaturated C18-fatty acid selected from oleic acid, linoleic acid and linolenic acid.
Patent CA-2624921-C (CA)
Inventor: GARCIA-RODENAS CLARA LUCIA
IPC: A23L33/00
Filed: 2006-10-02
Granted: 2012-07-10
Abstract: This invention relates to a nutritional formulation comprising an n3 long-chain polyunsaturated fatty acid (LC-PUFA), a prebiotic fibre and a probiotic bacterial strain which ingredients act together in a synergistic fashion to promote catch-up growth in young mammals whose growth has been retarded because the young mammal has been subjected to physical or mental stress.
Patent CA-2626532-C (CA)
Inventor: LIM GUEISAM
IPC: G01N1/00
Filed: 2008-03-19
Granted: 2013-04-23
Abstract: The bio chip and the apparatus for analyzing biological material are disclosed, the bio chip and the apparatus being capable of analyzing a variety of specific materials included in biological materials using a single bio chip injected with a single biological material, capable of conducting an optical measurement and an electro-chemical measurement to the enhancement of efficiency, capable of forming a sterilizer at the bio chip to enable a swift disinfection of vulnus caused by blood collection to the convenience of a user, and capable of mounting a laser beam source at the apparatus to enable a swift blood collection, wherein the apparatus is provided with a transfer unit for transferring the bio chip having a sterilizer, whereby the bio chip is transferred following the blood collection to enable automatic disinfection and analysis.
Patent CA-2635256-C (CA)
Title: Reflector support structure
Inventor: HIRUKAWA MASAYUKI
IPC: B62K5/01
Filed: 2008-06-18
Granted: 2012-09-11
Abstract: To provide a reflector support structure capable of reducing effect on the appearance of a vehicle body, while maintaining good visibility. In a vehicle including a wheel disposed on a vehicle body frame via a suspension, a fender covering an upward area of the wheel, a cross frame disposed on an inside of the fender and extending laterally across the vehicle body frame, and a cushion having an upper end attached to the cross frame, a reflector is disposed visibly from an outside of the vehicle body on the cross frame disposed on the inside of the fender.
Patent CA-2636412-C (CA)
Title: Method for operating a firing plant
Inventor: GARAY MAURICIO
IPC: F23N5/16
Filed: 2006-11-20
Granted: 2014-03-11
Abstract: A method for operating a firing plant with at least one combustion chamber and at least one burner, especially a gas turbine, includes an operating characteristic for operating the combustion chamber close to the lean extinction limit defined as a burner group staging ratio (BGV Rich) . Pressure pulsations (Puls Actual) measured in the combustion chamber are processed by a filter device (2) and converted into corresponding signals (Puls Actual,Filter(t)) .cndot. An exceeding/falling short of at least one pulsation limiting value (Puls Limit) is monitered by a monitoring device (3) and adapts a pulsation reference value (Puls Ref) in dependence upon the monitoring.  The processed pressure pulsations (Puls Actual,Filter(t)) are then compared with the adapted pulsation reference value (Puls Ref,adapt) , and, from this, a correction value .increment.BGV is determined, by which the burner group staging ratio (BGV Rich) is corrected, and as a result operation of the firing plant close to the lean extinction limit may be realized.
Patent CA-2636436-C (CA)
Inventor: BAERT LIEVEN ELVIRE COLETTE
IPC: A61P31/18
Filed: 2007-01-19
Granted: 2014-04-01
Abstract: This invention relates to the use of a parenteral formulation comprising an anti-virally effective amount of TMC278 or a pharmaceutically acceptable acid-addition salt thereof, and a carrier, for the manufacture of a medicament for the treatment of a subject being infected with HIV, wherein the formulation is to be administered intermittently at a time interval of at least one week.
Patent CA-2638193-C (CA)
Inventor: ABYLOV MELIS
IPC: A23G1/54
Filed: 2008-07-18
Granted: 2015-03-17
Abstract: Méthode de fabrication dun produit de confiserie comprenant les étapes suivantes : a) déposer au moins une masse de confiserie en lui permettant de se répandre dans un moule; b) déposer au moins une matière particulaire dans ou sur la masse de confiserie; et c) répéter au moins létape a) au moins une fois.
Patent CA-2644348-C (CA)
Title: Method for producing paper, paperboard and cardboard having high dry strength
Inventor: RUEBENACKER MARTIN
IPC: D21H17/42
Filed: 2007-03-09
Granted: 2014-06-10
Abstract: The invention relates to a method for producing paper, paperboard and cardboard having high dry strength by adding a vinylamine entity-containing polymer and lignosulfonic acid and/or a lignosulfonate to a paper pulp, dewatering the pulp and drying the paper products.
Patent CA-2645984-C (CA)
Inventor: EGGERT DANIEL M
IPC: B25B13/00
Filed: 2008-12-05
Granted: 2015-11-24
Abstract: A tool having a relatively ductile working end for engaging workpieces and a relatively hard non-working portion for driving the tool is disclosed, and a process for making same. The tool is formed with the material in a first state, such as by cold-working, and then only the non-working portion is heat treated to a second state. The working end is thus maintained in the ductile state while the non-working portion is hardened, thus imparting different materials performance characteristics to working end and non-working portion.
Patent CA-2653451-C (CA)
Title: Compositions and methods for inhibiting expression of ikk-b gene
Inventor: DE FOUGEROLLES ANTONIN
IPC: C12N15/63
Filed: 2007-05-21
Granted: 2015-12-29
Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the IKK-B gene, comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of the IKK-B gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression or activation of the IKK-B gene using the pharmaceutical composition; and methods for inhibiting the expression of the IKK-B gene in a cell.
Patent CA-2657591-C (CA)
Title: Pulsed-neutron formation density
Inventor: JACOBSON LARRY A
IPC: E21B47/00
Filed: 2007-06-29
Granted: 2012-09-11
Abstract: A method and related system of determining formation density by compensating actual inelastic gamma rays detected from a pulsed-neutron tool for the effects of neutron transport. The method and systems may model response of the tool and use the modeled response as an indication of an amount to compensate detected inelastic gamma rays.
Patent CA-2661421-C (CA)
Inventor: LARSEN JOERGEN GUTZON
IPC: H01M8/0282
Filed: 2009-04-06
Granted: 2016-11-22
Abstract: Solid oxide fuel cell stack obtainable by a process comprising the use of a glass sealant with composition 50-70 wt% SiO2, 0-20 wt%A12O3, 10-50 wt% CaO, 0-10 wt% MgO, 0-2 wt% (Na2O + K2O) , 5-10 wt% B2O3, and 0-5 wt% of functional elements selected from TiO2, ZrO2, F, P2O5, MoO3, Fe2O3, MnO2, La--Sr-Mn-O perovskite(LSM) and combinations thereof.
Patent CA-2663209-C (CA)
Inventor: PARK PETER U
IPC: C07K16/28
Filed: 2007-10-16
Granted: 2018-02-13
Abstract: Antibodies, humanized antibodies, resurfaced antibodies, antibody fragments, derivatized antibodies, and conjugates of same with cytotoxic agents, which specifically bind to CD38, are capable of killing CD38+ cells by apoptosis, antibody-dependent cell-mediated cytotoxicity (ADCC), and/or complement-dependent cytotoxicity (CDC). Said antibodies and fragments thereof may be used in the treatment of tumors that express CD38 protein, such as multiple myeloma, chronic lymphocytic leukemia, chronic myelogenous leukemia, acute myelogenous leukemia, or acute lymphocytic leukemia, or the treatment of autoimmune and inflammatory diseases such as systemic lupus, rheumatoid arthritis, multiple sclerosis, erythematosus, and asthma. Said derivatized antibodies may be used in the diagnosis and imaging of tumors that express elevated levels of CD38. Also provided are cytotoxic conjugates comprising a cell binding agent and a cytotoxic agent, therapeutic compositions comprising the conjugate, methods for using the conjugates in the inhibition of cell growth and the treatment of disease, and a kit comprising the cytotoxic conjugate. In particular, the cell binding agent is a monoclonal antibody, and epitope-binding fragments thereof, that recognizes and binds the CD38 protein.
Patent CA-2671286-C (CA)
Title: Dispositifs, systemes et procedes d'administration pour stimuler le tissu nerveux a de multiples niveaux spinaux
Inventor: IMRAN MIR A
IPC: A61N1/372
Filed: 2007-12-06
Granted: 2017-09-19
Abstract: La présente invention concerne des dispositifs, des systèmes et des procédés permettant de stimuler simultanément l'anatomie spinale à divers emplacements, tels que des niveaux spinaux, le long de la moelle épinière. La stimulation de multiples niveaux de la colonne vertébral au moyen d'un seul dispositif permet de créer une voie d'accès unique vers un boîtier de neuromodulation implantable (IPG) plutôt que des voies d'accès individuelles pour chaque conducteur à chaque niveau spinal vers un IPG. La diminution du nombre de voies d'accès réduit la complexité de la procédure, le temps et la récupération. De plus, certains modes de réalisation portent sur une spécificité additionnelle au sein de chaque niveau ciblé, telle qu'une stimulation sélective d'un tissu spécifique, notamment le ganglion de la racine dorsale.
Patent CA-2675672-C (CA)
Inventor: WYATT PETER JONATHAN
IPC: A46B13/08
Filed: 2008-02-21
Granted: 2013-12-03
Abstract: A cosmetic applicator includes a handle (102), a drive (104) coupled to the handle, an applicator head (106) coupled to the drive, and a torque limiter coupled to or within at least one of the drive and the applicator head such that the torque applied via the applicator head does not exceed a predetermined allowable torque.
Patent CA-2688640-C (CA)
Inventor: FABBRI WILLIAM C
IPC: F21S8/04
Filed: 2009-12-15
Granted: 2018-03-20
Abstract: A method of retro-fitting an existing luminaire housing comprises the steps of removing lighting components from the existing housing, fastening a first powertray retaining assembly to an end cap of the existing housing, fastening a second powertray retaining assembly to a second end cap of the existing troffer, telescoping a powertray to a size allowing the powertray to be moved through an opening in the existing housing, inserting the powertray through the opening in the existing housing and retaining the powertray on one of the first and second retaining assemblies, telescoping the powertray to engage the other of the first and second retaining assemblies and, positioning a diffuser in the troffer. A retro-fit luminaire assembly is also disclosed.
Patent CA-2689084-C (CA)
Title: Procede et appareil pour realiser une spectrometrie de masse
Inventor: MAKAROV ALEXANDER
IPC: H01J49/42
Filed: 2002-03-20
Granted: 2012-05-15
Abstract: Un spectromètre de masse comprend une source d'ions pour alimenter les ions de l'échantillon pour l'analyse, un piège à ions et une source de tension. Le piège à ions comporte une entrée pour recevoir les ions de l'échantillon et une sortie à travers laquelle les ions de l'échantillon sont libérés. La source de tension est configurée pour appliquer un premier ensemble de tensions de piégeage du piège à ions pour confiner les ions de l'échantillon dans le piège à ions. Le premier ensemble de tensions de piégeage est sélectionné pour engendrer un centre de nuage ionique défini par les ions de l'échantillon confinés dans le piège à ions positionné plus près de la sortie que de l'entrée. La source de tension est configurée pour appliquer une tension de relâchement au piège à ions conçue pour libérer les ions de l'échantillon du piège à ions par la sortie.
Patent CA-2691255-C (CA)
Inventor: CALVO MARIANO
IPC: E21B41/00
Filed: 2010-01-27
Granted: 2017-10-17
Abstract: A user interface for predicting the physical attributes of a proposed well by receiving formation top data for the proposed well; receiving formation top data and physical attribute data for offset wells; displaying an offset formation top graph and a proposed formation top graph; mapping one or more portions of the offset formation top graph to one or more portions of the proposed formation top graph; normalizing the physical attribute data associated with each mapped portion of the offset formation top graph to the associated mapped portion of the proposed formation top graph; displaying a normalized physical attribute graph of the normalized physical attribute data associated with each mapped portion of the offset formation top graph; selecting one or more portions of the normalized physical attribute graph; and determining the physical attribute data for the proposed well as the selected portions of the normalized physical attribute graph.
Patent CA-2693416-C (CA)
Title: Methods for reducing allergies caused by environmental allergens
Inventor: WELLS GEORGE
IPC: A61K39/395
Filed: 2008-07-09
Granted: 2018-01-09
Abstract: Compositions suitable for reducing symptoms of an allergic response to environmental allergens comprising molecules that specifically inhibit the ability of the allergen to bind to mast cells in an animal predisposed to having an allergic response to the allergen and methods for reducing such symptoms comprising contacting a source of the environmental allergen with such compositions. Kits, packages, medicaments, and means of communicating about the compositions and methods are also provided.
Patent CA-2696788-C (CA)
Inventor: OH YOUNGHOON
IPC: A61B17/86
Filed: 2008-04-29
Granted: 2012-01-31
Abstract: A dynamic screw system for stabilizing a vertebral body includes a bone screw adapted to connect to the vertebral body, the bone screw including an open concave head, a connecting element coupled to the bone screw, a joint element coupled around a middle cylindrical portion of the connecting element, an elongated bar element coupled to the upper spherical portion of the connecting element, and a pin adapted to fit inside the elongated bar element and a slot of the connecting element. The connecting element may include an upper spherical portion including a first diameter, a middle cylindrical portion including a second diameter less than the first diameter, and a lower spherical portion having a plurality of outwardly expandable legs adapted to lock into the open concave head of the bone screw.
Patent CA-2698054-C (CA)
Title: Coreference resolution in an ambiguity-sensitive natural language processing system
Inventor: VAN DEN BERG MARTIN HENK
IPC: G06F40/00
Filed: 2008-08-29
Granted: 2015-12-22
Abstract: Technologies are described herein for coreference resolution in an ambiguity-sensitive natural language processing system. Techniques for integrating reference resolution functionality into a natural language processing system can processes documents to be indexed within an information search and retrieval system. Ambiguity awareness features, as well as ambiguity resolution functionality, can operate in coordination with coreference resolution. Annotation of coreference entities, as well as ambiguous interpretations, can be supported by in-line markup within text content or by external entity maps. Information expressed within documents can be formally organized in terms of facts, or relationships between entities in the text. Expansion can support applying multiple aliases, or ambiguities, to an entity being indexed so that all of the possibly references or interpretations for that entity are captured into the index. Alternative stored descriptions can support retrieval of a fact by either the original description or a coreferential description.
Patent CA-2699781-C (CA)
Title: Commercial fischer-tropsch reactor
Inventor: IBSEN MARK
IPC: B01J19/00
Filed: 2008-09-09
Granted: 2014-08-05
Abstract: A catalytic reaction system comprising:  a catalytic reactor fluidly connected with at least two slurry loops, wherein the reactor comprises at least as many reactor product outlets and at least as many slurry return inlets as slurry loops; wherein each slurry loop comprises a separation system comprising a separation system inlet, a separation system product outlet, and a concentrated catalyst slurry outlet; a slurry offtake fluidly connecting the separation system inlet with one of the reactor product outlets; and a slurry return fluidly connecting the separation system outlet with one of the slurry return inlets. The system may comprise at least three slurry loops. The system may comprise at least four slurry loops. A method for converting synthesis gas into liquid hydrocarbons via the catalytic reaction system in also disclosed.