baber/WOPTO huggingface dataset:
Patent DE-69319438-T2 (DE)
Inventor: KLAVENESS JO
IPC: A61K49/18
Filed: 1993-09-03
Granted: 1998-12-03
Abstract: Proteinaceous gas- or gas precursor-containing microbubble contrast agents, e.g. for use in ultrasound and/or MR imaging, in which the protein matrix is crosslinked by reaction with a bifunctional aldehyde (e.g. a dialdehyde such as glutaraldehyde or an  alpha , beta -unsaturated aldehyde such as acrolein) in an aqueous medium at substantially neutral pH exhibit improved in vivo and storage stabilities, particularly if the matrix is also reacted with a Schiff's base reducing agent such as a borohydride. Modification of the size distribution of such crosslinked proteinaceous gas-containing contrast agents, e.g. to reduce the mean size of the microbubbles, further enhances their stability and permits preparation of novel contrast agents having a particularly narrow microbubble size distribution.
Patent DE-69319920-T2 (DE)
Inventor: OMURA SATOSHI
IPC: C12R1/66
Filed: 1993-03-26
Granted: 1998-12-10
Abstract: A FO-1289 substance of the formula   <IMAGE>   wherein R1, R2, R3 and R4 are hydrogen or acyl. A process for the production thereof comprises culturing the novel microorganism Aspergillus sp. FO-1289 FERM BP-4242 in a nutrient medium, accumulating the FO-1289 substance thus produced in the medium, and isolating the FO-1289 substance therefrom. Particular species of the FO-1289 substance comprise FO-1289A, in which R1, R2 and R3 are acetyl and R4 is hydrogen; FO-1289B, wherein R1 is propionyl, R2 and R3 are acetyl and R4 is hydrogen; FO-1289C, wherein R1 and R3 are acetyl, R2 is propionyl and R4 is hydrogen; and FO-1289D, wherein R1 and R2 are acetyl, R3 is propionyl and R4 is hydrogen.
Patent DE-69327254-T2 (DE)
Inventor: BRIGHT Gene
IPC: A61P25/18
Filed: 1993-09-30
Granted: 2000-03-30
Abstract: The compounds of formula (I), wherein A, R1, R3, Z and Y are as defined herein, have corticotropin-releasing factor (CRF) antagonist activity. They an useful in the treatment of illnesses induced by CRF, such as stress and anxiety related disorders. <CHEM>
Patent DE-69329637-T2 (DE)
Inventor: HEKSTRA ANDRIES PIETER
IPC: H04N7/26
Filed: 1993-09-03
Granted: 2001-05-10
Abstract: Known systems based on layered video coding and video decoding code with inadequate efficiency because the new high-resolution picture is predicted by means of the switching means present in the system either on the basis of the preceding high-resolution picture or on the basis of the instantaneous low-resolution picture. According to the invention, designing the switching means for the adjustment of the ratio of the signal representing the preceding high-resolution picture and the signal representing the instantaneous low-resolution picture and for then adding both the adjusted signals achieves a gain of 3 dB in the prediction with the correct ratio, and this results in an improvement in the coding efficiency. <IMAGE>
Patent DE-69406018-T2 (DE)
Inventor: ZANETTE DONATO
IPC: B21D43/11
Filed: 1994-07-06
Granted: 1998-02-19
Abstract: PCT No. PCT/EP94/02214 Sec. 371 Date Apr. 16, 1996 Sec. 102(e) Date Apr. 16, 1996 PCT Filed Jul. 6, 1994 PCT Pub. No. WO95/17984 PCT Pub. Date Jul. 6, 1995A gripper feeder for metal strip including on a base one pair of grippers for an engagement of a metal strip to be advanced; members for moving said grippers in a direction parallel to an axis of the strip and in the opposite direction; and means for independently operating the grippers such that the gripper which moves in the direction of advancement of the strip is activated, whereas that which moves in an opposite direction is deactivated.
Patent DE-69407890-T2 (DE)
Inventor: KANNO KATSUO
IPC: A63B102/02
Filed: 1994-06-30
Granted: 1998-04-30
Abstract: A racket string consists of lengthwise sections having different tensile elastic moduli with at least one section of the string having a tensile elastic modulus higher than other sections. A stringed racket includes at least one string constituting the central stringed area of the racket with higher tensile elastic modulus, and a peripheral stringed area with sections of the string having lower tensile elastic modulus. Another stringed racket includes at least one string constituting the central stringed area of the racket with lower tensile elastic modulus and a peripheral stringed area with sections of the string having higher tensile elastic modulus. <IMAGE>   <IMAGE>
Patent DE-69409078-T2 (DE)
Inventor: KINNUNEN JORMA
IPC: B65H19/28
Filed: 1994-12-15
Granted: 1998-08-06
Abstract: The invention concerns a method in reeling of a paper or board web in a drum reel-up or equivalent, in which, when a paper or board reel (R) formed on a reel spool (11) becomes complete, a new reel spool (11') is brought by means of transfer members (32) into a stand-by position and accelerated up to the web speed, the reel spool (11) with the reel (R) is transferred by means of a transfer device into an exchange position apart from the reel drum (10), and the new, initially accelerated reel spool (11') is transferred into the reeling position (12). When the reel spool (11) with its reel (R) is transferred into the exchange position apart from the reel drum (10), the belt (F) guide roll (21) is transferred into contact with the reel (R) that is being formed onto the reel spool (11), that the guide roll (21) is displaced along with the reel spool (11) into the exchange position so that the web (W) runs during the entire exchange on support of the belt (F) and through the nip (N3) between the guide roll (21) and the reel spool (11). The invention also concerns a device in reeling of a paper or board web in a drum reel-up or equivalent, which device comprises a reel drum (10) and a reel spool (11), the web (W) being fitted to run through the nip (N) between said drum and said spool onto the reel spool (11), which device comprises a transfer device (32) for bringing a new reel spool (11') into nip contact against the reel drum (10) after the paper or board reel (R) on the first reel spool has become complete. The device comprises means for the transfer of the belt (F) guide roll (21), together with the reel spool (11), into the exchange position, so that, during the entire exchange, the web (W) is supported on the belt (F) and fitted to run through the nip (N3) between the guide roll (21) and the reel spool (11). <IMAGE>
Patent DE-69410248-T2 (DE)
Inventor: BIRCHALL JAMES DEREK
IPC: A61K33/14
Filed: 1994-03-11
Granted: 1999-01-21
Abstract: PCT No. PCT/GB94/00484 Sec. 371 Date Nov. 6, 1995 Sec. 102(e) Date Nov. 6, 1995 PCT Filed Mar. 11, 1994 PCT Pub. No. WO94/20119 PCT Pub. Date Sep. 15, 1994A therapeutic composition for the treatment of virus-induced cutaneous infections comprises a first material for blocking viral DNA replication and a second finely divided material which absorbs exudated fluid from vesicles. Preferred compositions comprise a lithium compound (as the material for blocking viral DNA replication) and silica (as the material for absorbing exudated fluid from vesicles). An example of composition in accordance with the invention comprises a lithium compound dissolved or suspended in an aqueous silica salt.
Patent DE-69412279-T2 (DE)
Inventor: FARLEY JAMES
IPC: C08L101/00
Filed: 1994-09-14
Granted: 1999-01-07
Abstract: Heat sealed articles and heat sealable films comprising a polymer blend of a first polymer having a narrow molecular weight and composition distribution and a second polymer having a broad molecular weight distribution and composition distribution. The articles and films have significantly improved physical characteristics and remarkably low heat seal initiation temperatures, high seal strength, high hot tack and therefore provide improved processibility and higher line speeds on commercial heat sealing equipment.
Patent DE-69417925-T2 (DE)
Inventor: BAKSHI RAMAN
IPC: A61P13/02
Filed: 1994-10-31
Granted: 1999-11-25
Abstract: Compounds of formula (I) are inhibitors of 5 alpha -reductase and are useful alone or in combination with 5 alpha -reductase 1 and/or 2 inhibitors for the treatment of hyperandrogenic disorders such as acne vulgaris, seborrhea, female hirsutism, male pattern baldness, and benign prostatic hyperplasia.
Patent DE-69418461-T2 (DE)
Inventor: KIM SU
IPC: A61P43/00
Filed: 1994-07-22
Granted: 1999-09-09
Abstract: PCT No. PCT/KR94/00098 Sec. 371 Date Oct. 20, 1995 Sec. 102(e) Date Oct. 20, 1995 PCT Filed Jul. 22, 1994 PCT Pub. No. WO95/23140 PCT Pub. Date Aug. 31, 1995The present invention relates to a novel compound 5-pyrrolyl-2-pyridylmethylsulfinylbenzimidazole derivative having general formula (I) and its salt,    <IMAGE>  (I)  wherein all variables are as defined in the specification. The present invention also relates to a process for preparation of the compound of formula (I), as defined above, and its use as an anti-ulcer agent.
Patent DE-69423392-T2 (DE)
Inventor: HIRANO HIROFUMI
IPC: B41J2/175
Filed: 1994-07-18
Granted: 2000-08-31
Abstract: A preliminary ejection sensor (29) of an ink jet recording apparatus includes a vibration plate (296) adapted to vibrate on receipt of an ink droplet ejected from an ejection port (323c) on a recording head (32) in order to detect the vibration of the vibration plate (296) depending on variation of a gap between a core (292a) and the vibration plate, whereby it can be checked whether ink is ejected from the recording head or not. In addition, the preliminary ejection sensor can check the present ink ejecting state of the recording head. Thus, in contrast with a conventional sensing system wherein ink ejection is sensed by an optical sensor on one side surface of the recording head, the structure of the ink jet recording apparatus can be simplified. Additionally, in contrast with another conventional checking system wherein a temperature sensor is disposed on the recording head to indirectly check the present ink ejecting state of the recording head by monitoring the elevated temperature, the ink jet recording apparatus assures that a checking operation can quickly be achieved at a high accuracy. Consequently, the ink jet recording apparatus makes it possible to exactly detect whether or not ink is correctly ejected from ink ejection ports (323c) formed on the jet recording head (32). <IMAGE>
Patent DE-69500438-T2 (DE)
Inventor: DOBSON CHRISTOPHER
IPC: H01L21/00
Filed: 1995-02-09
Granted: 1998-04-02
Abstract: A chamber includes a door which opens to introduce a workpiece into the chamber and which closes to enclose the workpiece within the chamber. A workpiece support is located within said chamber and supports the workpiece such that a coated surface of the workpiece faces in a given direction. A liquid supply mechanism floods the chamber with a liquid to immerse the workpiece support. A pressure pulse supply mechanism applies a pulse of pressure to the liquid such that the pulse of pressure is transmitted through the liquid in a direction opposite the given direction. The pulse of pressure is incident via the liquid on the coated surface of the workpiece supported by the workpiece support.
Patent DE-69501161-T2 (DE)
Inventor: REUTELINGSPERGER CHRISTIAAN
IPC: G01N33/543
Filed: 1995-04-11
Granted: 1998-03-19
Abstract: PCT No. PCT/NL95/00134 Sec. 371 Date Oct. 11, 1996 Sec. 102(e) Date Oct. 11, 1996 PCT Filed Apr. 11, 1995 PCT Pub. No. WO95/27903 PCT Pub. Date Oct. 19, 1995A procedure to measure apoptosis in physiology and pathology in order to support clinical diagnosis and monitor efficacies of drugs and therapies. In particular a method for detecting and/or optionally quantifying and/or optionally isolating apoptotic cells in a sample, comprising contacting the sample with a detectable reagent having high affinity for phosphatidyl serine; and qualitatively and/or optionally quantitatively detecting cells that have reacted with the detectable reagent having high affinity for phosphatidyl serine preferably intact cells, detection occurring before or after an optional step for isolating apoptotic cells from non-apoptotic cells, which isolation can occur due to the fact that apoptotic cells have been provided with a detectable reagent having high affinity for phosphatidyl serine, the reagent also being selectable in a manner known per se. A suitable reagent having high affinity for phosphatidyl serine is a polypeptide or protein classified as an annexin. A kit for carrying out such methods is provided.
Patent DE-69505471-T2 (DE)
Inventor: PETETIN SYLVIE
IPC: H05B3/68
Filed: 1995-07-07
Granted: 1999-06-02
Abstract: The cooking hob includes a support table (1) made of steel covered on both surfaces with a layer of electrically insulating material (6). Within the table there are apertures (3) intended to receive heating plates. The heating plates are held within the apertures by means of a sealing ring (4) filling the space between ring edge and support plate. The heating plate is made of a support layer (7) of steel coated on both surfaces with electrically insulating material, and a layer which conducts electricity (8) consisting of conducting tracks, with connections (9) for linking the tracks to the electrical supply.
Patent DE-69505542-T2 (DE)
Inventor: MELLIN CHARLOTTA
IPC: C07D307/80
Filed: 1995-08-11
Granted: 1999-06-02
Abstract: PCT No. PCT/EP95/03214 Sec. 371 Date Apr. 7, 1997 Sec. 102(e) Date Apr. 7, 1997 PCT Filed Aug. 11, 1995 PCT Pub. No. WO96/05190 PCT Pub. Date Feb. 22, 1996The invention provides compounds according to the formula   <IMAGE>   in which: Ha=I or Br X=CH2 or C=O R1=C1-4 alkyl R2=-NHSO2R3; -NHCOR3; or -NHCONHR3 where R3=-CF3,C1-3 alkyl, 4-R4C6H4-; where R4=C1-4 alkoxy-; hydroxy-; fluoro-; or nitro-; or a pharmaceutically acceptable salt thereof. The compounds may particularly be used in the treatment of T3 regulated gene disorders and diseases.
Patent DE-69513445-T2 (DE)
Inventor: BERANGER MARIO
IPC: B32B15/08
Filed: 1995-03-15
Granted: 2000-04-06
Abstract: A process for applying a multilayer coating comprising a painlayer and a plastic filmlayer onto a metal coil or plate in which the paintlayer has adhesive properties thereby eliminating the need for a sole adhesive coating step.
Patent DE-69519082-T2 (DE)
Inventor: MULQUEEN J
IPC: A01N25/04
Filed: 1995-07-13
Granted: 2001-02-15
Abstract: A method of controlling the particle size and particle size distribution of an aqueous emulsion having a non-aqueous disperse phase during the production thereof, in which the production of the emulsion is carried out in the presence of a dispersion of a templating agent, such as a polymer latex, and surfactant Particle size and particle size distribution of the dispersion is controlled by selecting the templating agent and surfactant such as to cause deposition of the disperse phase on particles of the dispersed templating agent, such that the particle size distribution of the templating agent provides a template for the particle size distribution of the final emulsion.
Patent DE-69603880-T2 (DE)
Inventor: COUTTENIER ANDRE
IPC: B32B17/10
Filed: 1996-12-17
Granted: 2000-01-27
Abstract: PCT No. PCT/BE96/00133 Sec. 371 Date Jun. 16, 1998 Sec. 102(e) Date Jun. 16, 1998 PCT Filed Dec. 17, 1996 PCT Pub. No. WO97/22473 PCT Pub. Date Jun. 26, 1997Method for manufacturing a laminate consisting of at least two plates, which are attached to one another by means of an intermediate layer on the basis of a polymerizable resin, whereby a layer (7) of the polymerizable resin is applied on a horizontally placed plate (1) and whereby a second plate (9) is applied on this layer (7), after which the obtained whole is pressed together and the above-mentioned layer (7) is entirely polymerized, characterized in that between the application of the layer (7) and the application of the second plate (9), the layer (7) is first partly polymerized and this layer (7) is entirely polymerized after the whole has been pressed together.
Patent DE-69606319-T2 (DE)
Inventor: MARTIN PAUL MAXWELL
IPC: H04W72/04
Filed: 1996-11-08
Granted: 2000-07-13
Abstract: In a system in which control messages are transmitted in predetermined time slots within fixed length time frames from a first transmitting and receiving unit to a second transmitting and receiving unit, the second unit listens on a selected RF carrier frequency for an incoming message, the selected RF carrier frequency being selected from the class of RF frequencies available and preferred for use, the RF frequencies being classified dependent on whether communications on previously selected carrier frequencies have been successful.
Patent DE-69607233-T2 (DE)
Inventor: CATTANEO CARLO
IPC: A47B9/08
Filed: 1996-04-16
Granted: 2000-11-30
Abstract: An extensible leg, in particular but not exclusively for, furniture peninsulae, comprises, in combination: a first tube (11) and a second tube (12) screw-threaded in (14) and screwed on a screw-threaded sleeve (15) integral with an end of said first tube (11). Between said tube (12) and said sleeve (15) a locking means (21,19) is provided which can be shifted between a first position in which said tubes (11,12) can be screwed on each other, and a second position in which said tubes (11,12) are stably locked in their mutual position. <IMAGE>
Patent DE-69607330-T2 (DE)
Inventor: ROGELET THIERRY
IPC: F23Q2/28
Filed: 1996-10-03
Granted: 2000-08-03
Abstract: PCT No. PCT/IB96/01139 Sec. 371 Date May 15, 1998 Sec. 102(e) Date May 15, 1998 PCT Filed Oct. 3, 1996 PCT Pub. No. WO97/27431 PCT Pub. Date Jul. 31, 1997A lighter actuated by a push-control member (24) which can move in a longitudinal direction, and which resists use by children, comprising a lighter-body (2) and lighting means comprising said push-control member. The push-control member (24) is guided in two essentially perpendicular directions, a longitudinal direction (36) in relation to the lighter body (2) and a transverse direction (38, 56, 60) in relation to the lighter body (2). The push-control member (24) has an abutment face (34, 46, 52, 53) which is normally opposite a counter-abutment surface (34, 44, 2) integral with the lighter-body (2), and the push-control member (24) is displaceable in the transverse direction (38, 56, 60) such that its abutment face is then in a non-active position relative to its counter-abutment surface. Elastic means (40, 54, 58, 41, 62) comprising an elastic tongue member extending longitudinally and deformable transversely in accordance with transverse movement of the push-control member (24), act in a transverse direction (38, 56, 60) to return the abutment face of the push-control member to a position opposite the counter-abutment surface, means being provided to return the push-control member (24) into a position of rest in the longitudinal direction. Said elastic means may comprise a U-shaped metallic strip, one branch of which being elastically deformable, the second branch acting as an electrode forming electrical contact with the conductive material of a piezoelectric lighting system.
Patent DE-69612611-T2 (DE)
Inventor: KUBOTA MINEYUKI
IPC: A01N43/68
Filed: 1996-02-19
Granted: 2001-09-06
Abstract: The present invention relates to a triazine derivative of the general formula (I), <CHEM> (wherein X<1> is a linear or branched C1 SIMILAR C4 alkyl group or a halogen atom, n is an integer of 0 or 1 to 4, provided that when n is 2 or more, a plurality of substituents X<1> may be the same or different, and R<1> is a linear or branched C1 SIMILAR C10 alkyl group which may be substituted with 1 to 4 C1 SIMILAR C4 alkoxy groups and/or hydroxy groups, provided that when the linear or branched C1 SIMILAR C10 alkyl group is substituted with 2 or more C1 SIMILAR C4 alkoxy groups and/or hydroxy groups, a plurality of the C1 SIMILAR C4 alkoxy groups and/or hydroxy groups may be the same or different), a process for the production thereof, and a herbicide containing the above compound. The present invention provides a novel triazine derivative which shows remarkably excellent crops-weeds selectivity under the bad conditions of an excessive water content, etc., which are liable to cause phytotoxicity, and a herbicide containing it as an active ingredient.
Patent DE-69612963-T2 (DE)
Inventor: VAN ZANTEN EVERT
IPC: A01G9/00
Filed: 1996-02-13
Granted: 2001-09-20
Abstract: A process for producing hydrophilic growing media, preferably plugs, providing growing media having improved properties and a minimal amount of binding agent. The method forms a resilient, integral, dimensionally stable cohesive, homogeneous mass by contacting an aggregate with a hydrophilic urethane prepolymer and water. Upon curing, the prepolymer binds the aggregate material together. The mixing of the aggregate, prepolymer and water is conducted under specific, carefully controlled conditions, which enables the use of less prepolymer than would otherwise be necessary to obtain a given strength and stable air space. As result, trays can be filled without necessity of retooling.
Patent DE-69619861-T2 (DE)
Inventor: MATYUS PETER
IPC: A61K31/50
Filed: 1996-05-28
Granted: 2002-09-26
Abstract: The invention relates to R-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazinone of formula (1), and to S-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazinone of formula (2), and to acid-addition salts thereof as well as pharmaceutical compositions containing these compounds. Furthermore, the invention relates to a process for the preparation of the above compounds. The new starting compounds of formulae (4) and (5) are also involved in the scope of the invention. The compounds according to the invention possess alpha1- and alpha2-adrenoceptor antagonistic effects and urogenital selectivity. Thus, they are useful for the treatment of the benign prostate hyperplasia.
Patent DE-69621848-T2 (DE)
Inventor: THE PROCTER GAMBLE COMPANY CIN
IPC: A61F13/20
Filed: 1996-09-04
Granted: 2003-01-16
Abstract: PCT No. PCT/FI96/00469 Sec. 371 Date Jul. 8, 1998 Sec. 102(e) Date Jul. 8, 1998 PCT Filed Sep. 4, 1996 PCT Pub. No. WO97/09022 PCT Pub. Date Mar. 13, 1997The invention concerns a tampon (3), which can be inserted into the vagina, or other cavity, and which contains a molding cord (1) the pulling of which causes the tampon to increase its diameter and fill the cavity's inside diameter tightly.
Patent DE-69625827-T2 (DE)
Inventor: WHITE W
IPC: A44C3/00
Filed: 1996-12-23
Granted: 2004-01-22
Abstract: A one piece spring clip is provided which includes first and second relatively stiff elongate arms. Each arm has a gripping portion at one end and a jaw portion at an opposite end. A web interconnects the arms intermediate their ends, the web forming a pivot for the arms. A substantially U-shaped spring having a first end and a second end is disposed between the gripping portions of the arms. The first end of the spring is flexibly connected to one arm. A detent is formed on the other arm. The second end of the spring is resiliently biased to engage the detent when the gripping portions of the arms are initially moved toward each other, the spring yieldingly holding the jaws closed. The second end of the spring is continuously engaged in the detent for subsequent pressure and relaxation of pressure on the gripping portions of the arms to pivot the arms about the web, whereby the clamping portions of arms are movable toward and away from each other for receiving and retaining an object therebetween. Identification indicia, such as a badge is removably mounted to the clip by one of a plurality of mounting members formed on the clip.
Patent DE-69636791-T2 (DE)
Inventor: COOPER ROBIN DAVID GREY
IPC: C07K9/00
Filed: 1996-03-14
Granted: 2007-10-11
Abstract: The present invention provides glycopeptide antibiotic derivative compounds. These derivative compounds possess antibacterial activity against a wide variety of bacteria, including activity against vancomycin-resistant isolates. Methods of making and using these glycopeptide antibiotic derivative compounds are also provided.