baber/WOPTO huggingface dataset:
Patent EP-4059569-A1 (EP)
Title: Methods and pharmaceutical compositions for enhancing cd8+ t cell-dependent immune responses in subjects suffering from cancer
Inventor: HERMINE OLIVIER
IPC: G01N33/574
Filed: 2020-01-02
Abstract: Targeting immune checkpoints, such as Programmed cell Death 1 (PD1), has improved survival in cancer patients by unleashing exhausted CD8+ T-cell thereby restoring anti-tumor immune responses. Most patients, however, relapse or are refractory to immune checkpoint blocking therapies. Here, the inventors show that NRP1 is recruited in the cytolytic synapse of PD1+CD8+ T-cells, interacts and enhances PD-1 activity. In mice, CD8+ T-cell specific deletion of Nrp1 improves spontaneous and anti PD1 antibody anti-tumor immune responses. Likewise, in human metastatic melanoma, the expression of NRP1 in tumor infiltrating CD8+ T-cells predicts poor outcome of patients treated with anti-PDl (e.g. pembrolizumab). Finally, the combination of anti-NRPl and anti-PDl antibodies is synergistic in human, specifically in CD8+ T -cells anti-tumor response. Thus the therapeutic inhibition of NRP1 alone or combined with an immune checkpoint inhibitor (e.g. anti-PDl antibody) could efficiently repress tumor growth in human cancer. The present invention also relates to multispecific antibodies comprising at least one binding site that specifically binds to an immune checkpoint molecule (e.g. PD-1), and at least one binding site that specifically binds to NRP-1. The present invention also relates to a population of cells engineered to express a chimeric antigen receptor (CAR) and wherein the expression of NRP-1 in said cells is repressed.
Patent EP-4046690-A1 (EP)
Inventor: HOLLIS MICHAEL S
IPC: B63C11/22
Filed: 2022-02-17
Abstract: Systems and methods for emergency breathing systems are disclosed. Disclosed herein is a second stage regulator includes a housing, a first nosepiece coupled to a first lever, a second nosepiece coupled to a second lever, a first spring located in the housing and coupled to the first nosepiece and the first lever, a second spring located in the housing and coupled to the second nosepiece and the second lever, a mouthpiece, and a coupler coupled to the housing, wherein the first spring and the second spring bias the first nosepiece and the second nosepiece towards each other.
Patent EP-4239589-A1 (EP)
Inventor: TEICHMANN MARVIN
IPC: G06V10/774
Filed: 2022-03-01
Abstract: A method for AI-assisted generation of annotated medical images (WSI) is described. In the method, a set (S) of pre-annotated medical images (WSI) is received. Then the received set (S) is processed by automatically performing the steps of training an AI-based uncertainty model (BSM) using the received set (S) as training data. Then, a step of processing medical images (WSI) of the received set (S) by determining classified segments (SG) and/or uncertainty regions (UR) in the medical images (WSI) using the trained AI-based uncertainty model (BSM) follows. Further, a step of selecting at least a part of the processed medical images (WSI) including classified segments and/or uncertainty regions (UR) based on the processing result and presenting the selected part of processed medical images (WSI) to a human expert (HE) is performed. Furthermore, a modified received set (S') including additional annotations (AA) created by the human expert (HE) is received. The mentioned steps can be repeated using the modified set (S') of medical images (WSI) as training data, until a predetermined quality criteria for the annotated medical images (WSI) is achieved. Further, an annotation assistance device (10) is described. Furthermore, a computer-implemented method for providing a segmented medical image is described.
Patent EP-4249824-A1 (EP)
Title: Cap element with centering mechanism
Inventor: KIEFFER DAMIEN
IPC: F24H1/18
Filed: 2022-03-21
Abstract: Cap element (5) for a heating device (2), the heating device (2) including a water tank (3) located in a casing (4) and a cap element (5) placeable on or in the casing (4) for closing said casing (4), the cap element (5) comprising a centering mechanism integrated in, or removable from, the cap element (5), the centering mechanism having a deformable structure (6) for causing the cap element (5) to be centered relative to the water tank (3) upon exerting a mechanical pressure on said deformable structure (6).
Patent EP-4116752-A1 (EP)
Inventor: O'KEEFFE CONOR
IPC: G02B6/42
Filed: 2022-03-25
Abstract: An integrated circuit (IC) package comprising an optical die comprising a configurable optical switch. The configurable optical switch comprises an optical switch operably coupled to one or more optical transceivers. An optical connector comprises at least one exo-package optical port. The at least one exo-package optical port is operably coupled to the configurable optical switch. The configurable optical switch is to pass an optical signal on the at least one of the one or more exo-package ports to at least one of the one or more optical transceivers, and an IC die comprising electronic circuitry is operably coupled to the one or more optical transceivers.
Patent EP-4258497-A1 (EP)
Title: Enclosure for electrical equipment
Inventor: NIETO CARLOS
IPC: H02B13/025
Filed: 2022-04-06
Abstract: The present invention relates to the field of enclosures for electrical equipment, such as electrical power equipment and/or electronic equipment, and more particularly to an enclosure for electrical equipment. The enclosure (1) for electrical equipment according to the present invention comprises a frame portion (3) and a roof portion (4) arranged on top of and covering said frame portion (3), said roof portion (4) comprising an at least one inclined roof element (5), wherein said at least one inclined roof element (5) comprises an at least one rectangular opening (10) and respectively an at least one rectangular cover (20) arranged at the centre portion of said at least one inclined roof element (5), wherein said rectangular cover (20) is fastened from its bottom side to the inclined roof element (5) with a secure fastening arrangement (21), and said rectangular cover (20) is semi-securely fastened from its top side to the inclined roof element (5) with a semi-secure fastening arrangement (13, 23, 31, 32).
Patent EP-4109970-A1 (EP)
Inventor: TRAN EMILE MINH
IPC: H04W36/32
Filed: 2022-05-23
Abstract: A base station and computing resources to be used by a user equipment (UE) within a network can be selected based on information, such as an identification of base station(s) that may be used by the UE, and the location and performance of the base station(s) and the available computing resources. In some examples, when a mobility controller determines to switch the base station for a UE, the computing resources used to perform application processing can also be switched. For instance, when the current base station is switched, the computing resources used to perform application processing for the UE may be moved to computing resources that are closer to the different base station. In other examples, the mobility controller may determine to delay switching the UE to the different base station if the performance of the mobile application would be better using the current base station and current computing resources.
Patent EP-4156037-A1 (EP)
Inventor: HARA YASUSHI
IPC: G06N3/08
Filed: 2022-05-23
Abstract: A machine learning program that causes at least one computer to execute a process, the process includes acquiring a first training rate of a first layer that is selected to stop training among layers included in a machine learning model during training of the machine learning model; setting a first time period to stop training the first layer based on the training rate; and training the first layer with controlling the training rate up to the first time period.
Patent EP-4109532-A1 (EP)
Inventor: WALDEMER JAMES
IPC: H01L27/08
Filed: 2022-05-24
Abstract: Disclosed herein are IC structures with three-dimensional capacitors with double metal electrodes provided in a support structure (e.g., a substrate, a die, a wafer, or a chip). An example three-dimensional capacitor includes first and second capacitor electrodes and a capacitor insulator between them. Each capacitor electrode includes a planar portion extending across the support structure and one or more via portions extending into one or more via openings in the support structure. The capacitor insulator also includes a planar portion and a via portion extending into the via opening(s). The planar portion of the capacitor electrodes are thicker than the via portions. Each capacitor electrode may be deposited using two deposition processes, such as a conformal deposition process for depositing the via portion of the electrode, and a sputter process for depositing the planar portion of the electrode.
Patent EP-4098564-A1 (EP)
Inventor: MAIR ROLAND
IPC: B64D11/06
Filed: 2022-06-02
Abstract: A resting area system (100) and method for an internal cabin of a vehicle includes a monument (102), and a bed module (104) coupled to the monument (102). The bed module (104) includes one or more beds (132). The bed module (104) is moveable between a stowed position and a deployed position relative to the monument (102).
Patent EP-4112949-A1 (EP)
Title: Rastbolzen, elektronikmodul und herstellverfahren
Inventor: LÖWEN NIKOLAJ
IPC: F16B21/08
Filed: 2022-06-03
Abstract: Die vorliegende Erfindung betrifft einen Rastbolzen (1) zum Verbinden von Bauteilen eines Elektronikmoduls, zur Einführung und kraft- und/oder formschlüssigen in ein mindestens teilweise umschließendes Aufnahmeelement, umfassend mindestens einen Auflageabschnitt (4) und einen ersten Bolzenabschnitt (2) mit einem Kopfende (6) und einem verbindenden Halsabschnitt (8), wobei mindestens ein ein- oder mehrteiliger Schneid- und/oder Reibkranz (6,9) im Bereich des Kopfendes und/oder des Halsabschnittes angeordnet ist, wobei ein zweiter Bolzenabschnitt (3) an der Rückseite des Auflageabschnitts angeordnet ist, wobei der zweite Bolzenabschnitt ein Kopfende (5) und einen verbindenden Halsabschnitt (7) aufweist, und wobei mindestens ein ein- oder mehrteiliger Schneid- und/oder Reibkranz (5) im Bereich des Kopfendes und/oder des Halsabschnittes angeordnet ist. Weiterhin ist ein Elektronikmodul und ein Herstellverfahren umfasst.
Patent EP-4106199-A1 (EP)
Title: Dispositif de sélection de tension d'alimentation avec commutations contrôlées en tension et en courant
Inventor: AWAD MOHAMAD
IPC: H03K17/16
Filed: 2022-06-10
Abstract: L'invention propose différents modes de réalisation d'une architecture de circuit de sélection permettant de réaliser des transitions montante et/ou descendante selon des jeux de séquencement de phases lentes et rapides de manière à résoudre en même temps les problèmes de bruits inductifs de commutation et les problèmes de courants dans les rails d'alimentations. Cette solution présente plusieurs avantages liés à la facilité d'implémentation et la flexibilité de configurations possibles pour d'adapter aux contraintes spécifiques lors de la conception du circuit.
Patent EP-4249123-A1 (EP)
Inventor: CHI-SHENG TAI
IPC: B01L7/00
Filed: 2022-06-17
Abstract: The present invention discloses a multi-function polymerase chain reaction device, which utilizes a movable multi-functional top cover to make an equipment can selectively perform variable temperature PCR (Polymerase Chain Reaction) or constant temperature PCR, which the flexibility of test-application is highly raised.
Patent EP-4149165-A1 (EP)
Title: Systems, methods, and devices for optimizing radio access technology and resource selection
Inventor: DHANAPAL MUTHUKUMARAN
IPC: H04W36/00
Filed: 2022-06-29
Abstract: Techniques described herein may enable a user equipment (UE) to optimize radio access technology (RAT) and radio resources (e.g., bandwidth parts (BWPs)) when communicating with the network. This may be based on one or more factors or conditions, such as whether the UE is currently using 4th generation (4G) RAT or 5th generation (5G) RAT, whether the UE is in an active mode or idle mode, a BWP used by the UE, whether an application or network service requires a certain throughput, a type of application being used by the UE, an amount of network congestion, and so on. RAT optimization may also be based on whether the UE is using a frequency range 1 (FR1) or frequency range 2 (FR2), whether the UE is stationary or moving, whether the UE is experiencing beam failures, uplink (UL) switches, link quality measurements (LQMs), reference signal received power (RSRP) measurements, and so on.
Patent EP-4125151-A1 (EP)
Title: Secondary battery
Inventor: MOON JIN YOUNG
IPC: H01M50/559
Filed: 2022-06-29
Abstract: A secondary battery includes: an electrode assembly including a first electrode plate, a second electrode plate, and a separator; a can having a closed upper surface with a rivet opening therein and an open lower surface to accommodate the electrode assembly, the can being electrically connected to the first electrode plate; a rivet terminal in the rivet opening and electrically connected to the second electrode plate; a gasket between the can and the rivet terminal; and a cap plate sealing the lower surface of the can.
Patent EP-4092759-A1 (EP)
Title: Solar cell panel
Inventor: KIM JINSUNG
IPC: H01L31/0224
Filed: 2015-09-28
Abstract: A solar cell is disclosed. The disclosed solar cell includes a semiconductor substrate, a conductive region disposed in or on the semiconductor substrate, and an electrode including a plurality of finger lines connected to the conductive region, and formed to extend in a first direction while being parallel, and 6 or more bus bar lines formed to extend in a second direction crossing the first direction. Each bus bar line has a width of 35 to 350µm at at least a portion thereof. Each bus bar line has a distance between opposite ends thereof in the second direction smaller than a distance between outermost ones of the finger lines respectively disposed at opposite sides in the second direction.
Patent EP-4096153-A1 (EP)
Title: Map information management system
Inventor: TSUDA YOSHIAKI
IPC: H04L9/08
Filed: 2016-08-31
Abstract: When providing map information via a plurality of organizations, a map information management system which prevents data alteration of the map information and confirms data authenticity of the map information is obtained. The map information management system includes a map company exclusive application data management device that confirms data authenticity from encrypted data obtained from a dynamic map data management device and generates encrypted data from data which is added map company exclusive application data to dynamic map data by a map company exclusive secret key, and an automotive data management device that obtains data which is added map company exclusive application data to dynamic map data from the map company exclusive application data management device, confirms data authenticity that is added map company exclusive application data to dynamic map data with using a map company exclusive application data public key, and generates encrypted data from data with automotive company exclusive application data by an automotive company exclusive application data secret key.
Patent EP-4102502-A1 (EP)
Inventor: ANBAZHAGAN VIKRAM SATHYANARAYANA
IPC: G06F40/35
Filed: 2017-11-22
Abstract: A natural language understanding model is trained using respective natural language example inputs corresponding to a plurality of applications. A determination is made as to whether a value of a first parameter of a first application is to be obtained using a natural language interaction. Using the natural language understanding model, at least a portion of the first application is generated.
Patent EP-4163496-A1 (EP)
Inventor: MILLER JAMES
IPC: F04D1/00
Filed: 2022-10-10
Abstract: A variable speed pumping system including a variable speed pump, a remote user device, and an auxiliary device is provided. The variable speed pump includes a motor, a drive, a housing including a drive cover, and an onboard controller. The onboard controller includes a plurality of buttons formed in the drive cover, a touchscreen interface positioned on the drive cover, a main circuit board including a non-transitory computer readable medium, the main circuit board being electrically coupled to the touchscreen interface, the motor, and the drive, a wireless communication unit electrically coupled to the main circuit board, and a selectively removable IO expansion module. The onboard controller is configured to control one of a flow rate of the pump or a speed of the motor for a period time and actuate the auxiliary device based on input received on one of the onboard controller or the remote user device.
Patent EP-4169489-A1 (EP)
Inventor: WILLE THOMAS
IPC: A61F2/91
Filed: 2022-10-20
Abstract: Die vorliegende Erfindung betrifft einen Stent zur transluminalen Implantation in Hohlorgane, insbesondere in Blutgefäße, Harnleiter, Speiseröhren, Colon, Duodenum, Luftwege oder Gallenwege, mit einem zumindest im Wesentlichen röhrenförmigen Körper, welcher sich entlang einer Längsrichtung erstreckt und der von einem komprimierten Zustand mit einem ersten Querschnittsdurchmesser in einen expandierten Zustand mit einem vergrößerten zweiten Querschnittsdurchmesser überführbar ist, wobei der Stent einen Stentkörper aus einem biostabilen Material umfasst, dadurch gekennzeichnet, dass der Stentkörper mehrere, insbesondere voneinander separate, bevorzugt ringförmige, Stentabschnitte umfasst, und der Stent eine Stützstruktur aufweist, welche die Stentabschnitte miteinander verbindet, wobei die Stützstruktur aus einem bioresorbierbaren Material geformt ist oder ein bioresorbierbares Material umfasst.
Patent EP-4180849-A1 (EP)
Inventor: WU CHIN-TSUNG
IPC: G02B6/293
Filed: 2022-11-10
Abstract: A passive optical network dual system module includes a light guide unit, an optical path conversion unit and an optical transceiver unit. The light guiding unit is connected to the optical fiber and is suitable for transmitting optical signals. The optical path conversion unit is connected to the light guide unit, and is suitable for receiving optical signals and changing the optical path of the optical signals. It is used in the optical transceiver unit for the configuration of two receiving parts and two transmitting parts, which can support the same optical path at the same time with use of two sets of communication protocol systems.
Patent EP-4198931-A1 (EP)
Inventor: JOSEPH JESLIN PAUL
IPC: G08B13/196
Filed: 2022-11-25
Abstract: A monitored area including a plurality of video cameras is monitored for possible events. A video camera captures a video stream showing a portion of the monitored area and performs video analysis on the captured video stream. When the video camera identifies an event of interest within the captured video stream, the video camera generates event information associated with the identified event of interest. The video camera uses the relative location information to determine which video camera of the plurality of video cameras is positioned to capture the event of interest now and/or in the future and instructs that video camera to track the event.
Patent EP-4193836-A1 (EP)
Inventor: FÜLBIER CHRISTOPH
IPC: A21B1/10
Filed: 2022-11-29
Abstract: Hybrid-Thermoölerhitzer 1 für eine Backofenanlage 100 aufweisend einen elektrischen Erhitzer 10 zum Erhitzen von Thermoöl 70 und einen befeuerten Erhitzer 20 zum Erhitzen des Thermoöls 70, wobei der elektrische Erhitzer 10 und der befeuerte Erhitzer 20 strömungstechnisch in Reihe verschaltet sind. Weiterhin wird eine Backofenanlage 100 aufweisend einen Hybrid-Thermoölerhitzer 1 sowie ein Verfahren zum Beheizen einer Backofenanlage 100 beansprucht.
Patent EP-4187027-A1 (EP)
Title: Method and control system of a hydraulic circuit of a work vehicle
Inventor: GARRAMONE ADRIANO
IPC: E02F9/22
Filed: 2022-11-29
Abstract: Control system of a hydraulic circuit (HB) of a work vehicle (CWL), the hydraulic circuit comprising a hydraulic pump (P) and an electric motor (M) operatively connected to the hydraulic pump to drive it in rotation, two or more actuators hydraulic (BOOM, BUCKET,...) and corresponding two or more directional valves (V1, V2,...) with open center and corresponding two or more control levers (JOYSTICK) and a processing unit (CONTROL UNIT). The processing unit is configured to set a rotation speed of the electric motor proportional to a sum of the deflections of the two or more control levers, and to calculate, for each of said two or more directional valves (V1, V2, ...) , an opening value of the valve according to a function of the value of the corresponding deflection and the values of the deflections of the remaining one or more control levers, and subsequently to set said calculated opening value.
Patent EP-4202355-A1 (EP)
Title: Modular configuration for coordinate measuring machine probe
Inventor: KEEHNEL DAWN ALISA
IPC: G01B5/012
Filed: 2022-12-13
Abstract: A modular configuration for a scanning probe for a coordinate measuring machine include a stylus suspension module, a stylus position detection module, and a signal processing and control circuitry module. The stylus position detection module is configured to be assembled separately from the stylus suspension module before mounting to the stylus suspension module. The signal processing and control circuitry module is configured to be assembled separately from the stylus position detection module and the stylus suspension module before rigidly coupling to the stylus position detection module as part of assembling the scanning probe.
Patent EP-4207832-A1 (EP)
Inventor: YOSHIHARA TORU
IPC: H04W4/80
Filed: 2022-12-13
Abstract: An information processing device, includes: a memory; and a processor coupled to the memory, the processor being configured to: correct a signal strength of electrical power-saving communication based on a distance measurement between a vehicle (200) and a portable information terminal (30) calculated from a result of communication by ultra-wideband communication that temporarily has been put into an on state, initiate distance measurement between the vehicle (200) and the portable information terminal (30) by the ultra-wideband communication in a case in which the corrected signal strength is equal to or higher than an operation allowable threshold value, and enable control of the vehicle (200) so as to perform at least one of locking, unlocking or engine starting of the vehicle (200) in accordance with an operation signal transmitted from the portable information terminal (30) by the electrical power-saving communication.
Patent EP-4202226-A1 (EP)
Inventor: KISUN GAVIN ROHITESHWAR
IPC: F01D25/28
Filed: 2022-12-20
Abstract: An alignment tool (40) for aligning a plurality of diffuser pipes of a centrifugal compressor relative to a casing of an aircraft engine. The alignment tool (40) includes a body (46) defining a center axis (11, 41) and having at least one tool datum (42) configured for abutting against the casing. A plurality of alignment members (44) are fixed to the body (46) and extend radially from the body (46) relative to the center axis (11, 41). Each alignment member (44) of the plurality of alignment members (44) has a respective fixed position relative to the at least one tool datum (42). The plurality of alignment members (44) are configured to abut the plurality of diffuser pipes (20).
Patent EP-4129950-A1 (EP)
Inventor: SKYTTÄ OLLI
IPC: C04B28/04
Filed: 2022-08-01
Abstract: According to an example aspect of the present invention, there is provided a concrete composition comprising furnace slag, stone aggregate, an additive, Portland cement, and an activator, wherein the amount of furnace slag is 2 - 15 % by weight of the dry matter of the composition. According to another aspect of the present invention, there is provided a method for manufacturing a concrete element utilising the provided concrete composition.