baber/WOPTO huggingface dataset:
Patent BR-122019016866-B1 (BR)
Title: Método para avaliar (analisar) o risco dos efeitos adversos potenciaispara um paciente humano mediados pela administração de um anticorpobiespecífico de cd19xcd3
Inventor: DIRK NAGORSEN
IPC: G01N33/574
Filed: 2010-10-27
Abstract: uso de anticorpo biespecífico de cd19xcd3 no tratamento de linfócitos cd19-positivos malignos em um paciente humano tendo uma razão de células b:t de cerca de 1:5 ou menor. a presente invenção refere-se a um método para avaliar (analisar) o risco dos efeitos adversos potenciais para um paciente humano mediados pela administração de um anticorpo biespecífico de cd19xcd3 ao dito paciente compreendendo determinar a razão de células b para células t do dito paciente, em que uma razão de cerca de 1:5 ou menor é indicativo para um risco de efeitos adversos potenciais para o dito paciente. consequentemente, a presente invenção refere-se a um método (regime de dosagem) para administrar um anticorpo biespecífico de cd19xcd3 a um paciente humano tendo uma razão de células b:t de cerca de 1:5 ou menor, compreendendo (a) administrar uma primeira dose do dito anticorpo durante um primeiro período de tempo; e consecutivamente (b) administrar uma segunda dose do dito anticorpo durante um segundo período de tempo, em que a dita segunda dose excede a dita primeira dose. um pacote ou kit farmacêutico compreendendo uma primeira dose e uma segunda dose e opcionalmente uma terceira dose do dito anticorpo como definidas nos métodos/regime de dosagem da presente invenção é também revelado.
Patent BR-122022004403-B1 (BR)
Title: Material laminado
Inventor: JERALD T JASCOMB
IPC: A41D13/12
Filed: 2017-05-03
Abstract: A presente invenção trata de um material laminado. O material laminado compreende um filme elástico (144) respirável ao vapor de umidade, impermeável a líquidos, posicionado entre um primeiro material (142) e um segundo material (146). O filme elástico, o primeiro material e o segundo material incluem, cada um, um pigmento negro de fumo e dióxido de titânio. O filme elástico inclui ainda um aditivo fluoroquímico e o primeiro material e o segundo material incluem ainda aditivo de deslizamento. O material laminado apresenta uma opacidade superior a cerca de 98% e uma transmitância de luz inferior a cerca de 0,1.
Patent BR-122022009886-B1 (BR)
Title: Método para fabricação de um produto de celulose, aparelho de formação de produto de celulose, e, produto de celulose
Inventor: OVE LARSSON
IPC: B65B43/08
Filed: 2017-03-16
Abstract: Um método para fabricação de um produto de celulose, compreendendo as etapas: formar a secagem de uma peça bruta de celulose em uma unidade de formação a seco; arranjar a peça bruta de celulose em um molde de formação; aquecer a peça bruta de celulose até uma temperatura de formação na faixa de 100°C a 200°C; e pressionar a peça bruta de celulose no molde de formação com uma pressão de formação de pelo menos 1 MPa.
Patent CS-234040-B2 (CS)
Title: Coupling device especially for textile machine
Inventor: SPEICH FRANCISCO
IPC: F16D11/06
Filed: 1982-01-08
Abstract: In a coupling arrangement for a textile machine, a drive shaft can be intermittently rotated and a connecting member encircles and is connected to the drive shaft by an eccentric hoop located between them. A coupling key is displaceable between a first coupling recess associated with the drive shaft and a second coupling recess associated with the connecting member. The coupling key is retained in the recesses by lead cams. A retaining key, independent from the coupling key, is supported by the eccentric hoop. The retaining key cooperates with a first retaining recess on the drive shaft or with a second retaining recess on the connecting member. The retaining key and/or the retaining recesses have control surfaces which provide the displacement of the retaining key when the drive shaft overtakes the eccentric hoop or the eccentric hoop overtakes the connecting member.
Patent MA-38484-B2 (MA)
Title: Compositions antimicrobiennes et procédés d'utilisation associés
Inventor: GANDHI NIRANJAN
IPC: A01N43/16
Filed: 2015-10-12
Abstract: L'invention porte sur des compositions antimicrobiennes comprenant un ou plusieurs composants composites généralement reconnus comme sans danger pour la consommation humaine et sur des procédés d'utilisation associés, lesdites compositions et lesdits procédés pouvant être utilisés dans une large gamme de produits et d'applications agricoles, industriels, de construction, pharmaceutiques , de soins personnels et/ou de soins pour les animaux.
Patent CS-274864-B2 (CS)
Title: Method of frequency qualities' diffractometric measuring with device for image photochemical recording
Inventor: HOLAN JIRI RNDR CSC
IPC: G02B27/42
Filed: 1988-03-11
Abstract: The solution concerns a measuring of ability to display fine structure in devices for transmission and recording of image, i.e. measuring properties connected with the function of transmission of modulation, sharpness, and resolution capabilities. The principle of the solution consists in a diffractometric analysis of image record, made by the measured device for image transmission, where test diagram is displayed, with at least two systems of periodically arranged elements, which differ in space frequencies. From the ratio of intensities of deflection maxims frequency properties of the measured device are evaluated. The procedure is intended mainly for measuring of properties of device for copying, enlarging etc. of image for photographic materials.
Patent CS-199590-B2 (CS)
Title: Process for preparing refractory layered pressed matters
Inventor: FRANZ ARNOLD
IPC: C09K21/14
Filed: 1975-06-03
Abstract: 1510218 Flame retardant impregnated sheet structure DYNAMIT NOBEL AG 23 May 1975 [4 June 1974] 22739/75 Heading DIP [Also in Divisions B5 and C3] A process for the production of a fireretardant impregnated sheet structure for use in the production of a laminated structure comprises impregnating a woven or non- woven fibrous sheet structure with a phenolresol resin-containing impregnating solution and drying the impregnated sheet to further condense the resin, the resin being an ammonically condensed resin having a solids content of from 50 to 80% by weight and the following molecular weight distribution as determined by gel chromatography (expressed in % per unit area): dimers 20 to 26%, trimers and tetramers 6 to 12%, pentamers and higher oligomers 22 to 36%; the impregnating solution additionally containing hexamethylene tetramine in a quantity of from 1 to 15% by weight thereof, a plasticiser and a flame proofing agent. The sheet may be paper, a woven or non-woven synthetic fibre fabric or may be formed of glass fibres. Specified plasticisers are tributyl phosphate, tri-(2-ethyl-hexyl) phosphate, triphenyl phosphate, tricresyl phosphate and diphenyl cresyl phosphate; the exemplified flame-proofing agent being pentabromodiphenyl ether.
Patent CS-268688-B2 (CS)
Title: Method of substituted imidazopyrrole,-pyridine and-azepine derivatives production
Inventor: BROWNE LESLIE J DR
IPC: C07D487/04
Filed: 1986-11-05
Abstract: (A) Bicyclic imidazole derivs. of formula (Ia)-(Ic) and their salts are new. R1=H; alkyl opt. substd. by alkanoyl, NH2, mono- or dialkylamino, SO3H, COOH, alkoxycarbonyl, CONH2 or CN; 2-7C alkyl substd. by OH, alkoxy, halogen or alkanoyloxy; NO2, alkoxy, alkanoyl alkanoyloxy, phenylsulphonyloxy, alkylsulphonyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkanoylthio, NH2, mono- or dialkylamino, alkylenamino, morpholino, thiomorpholino, 1-piperazinyl, 4-alkyl-1-piperazinyl, trialkylammonio, SO3H, alkoxy sulphonyl, SO2NH2, mono- or dialkylsulphamoyl; iminomethyl opt. N-substd. by OH, alkoxy, alkanoyloxy, alkyl, phenyl or NH2; 2-7C alkanoyl or benzoyl; R2=H, alkyl, phenylalkyl, carboxyalkyl, alkoxycarbonylalkyl, halogen, OH, alkoxy, alkanoyloxy, SH, alkylthio, phenylalkylthio, phenylthio, alkanoylthio, COOH, alkoxycarbonyl or alkanoyl; R'1=R1, CH2OH, alkoxymethyl, halomethyl, alkanoyloxymethyl, halogen, OH, SH, CHO, COOH, alkoxycarbonyl, CONH2, mono- or dialkylcarbamoyl, CN, 5-tetrazolyl, 4,5-dihydro-2-oxazolyl (opt. substd. by alkyl) or CONHOH, n=0-4; R''1 =R1 or may be R'1 when n=0, 1, 3 or 4 or when n=2 and R2=phenyl alkyl, carboxyalkyl, alkoxycarbonylalkyl, alkanoyloxy, SH, alkylthio, phenylalkylthio, phenylthio, alkanoylthio, COOH, alkoxycarbonyl or alkanoyl; all alkyl, alkoxy and alkanoyl gps. are 'lower' unless otherwise stated; all phenyl gps. are opt. substd. by alkyl, alkoxy or halogen. - (B) The use of cpds. (Ia, R1=R, R2=R') (Ib: R'1=R, R2=R') and (Ic; R''1=R1, R2=R') for prepn. of medicaments for treating diseases responding to aromatase inhibition is claimed, where: R= H, opt. substd. alkyl, NO2, halogen, opt. etherified or esterified OH, opt. etherified, oxidised-etherified or esterified SH, NH2, mono- or disubstd. amino, ammonio, opt. functionally modified SO3H, COOH or CHO or 2-20C acyl; R'=H, opt. substd. alkyl, halogen, opt. etherified or esterified OH, opt. etherified, oxidised-etherified or esterified SH, opt. functionally modi
Patent JP-3080629-B2 (JP)
IPC: C07D471/04
Filed: 1990-01-16
Granted: 2000-08-28
Abstract: New benzo[b][1,8]naphthyridine derivatives of general formula (I), in which R is a hydrogen atom or an alkyl, fluoroalkyl, cycloalkyl (3 to 6 C), alkoxy or alkylamino radical or an amine protective radical and either Hal is a fluorine, chlorine or bromine atom and R' is a hydrogen atom or Hal and R' are simultaneously fluorine atoms, their salts, their preparation and the compositions which contain them. These new products can be used as antimicrobial agents for topical application or as synthesis intermediates.   <IMAGE> (I)
Patent AU-766947-B2 (AU)
Title: Apparatus and method for declustering cherries
Inventor: OPEDAL LEIF GUNNAR
IPC: A23N15/02
Filed: 2000-10-03
Granted: 2003-10-30
Abstract: An apparatus and method for declustering cherries, comprising a plurality of oscillating cutting modules (36), each having a power driven shaft (40) with a plurality of circular blades (42) fixed along its length. The modules further comprise cutting ramps (46) having a tail section (48) extending under the blades, such that the clusters are suspended from their nodes at the moment of cutting. The height of tail sections (48) may be adjusted to accommodate cherry varieties having different stem lengths.
Patent AU-779198-B2 (AU)
Title: Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
Inventor: GAO GUANG-PING
IPC: C12P21/04
Filed: 2000-09-12
Granted: 2005-01-13
Abstract: Novel cell lines useful for trans-complementing E1-deleted adenoviral vectors are described. The cell lines are capable of providing high yields of E1-deleted adenoviral vectors in the absence of replication-competent adenovirus over multiple passages.
Patent AU-591385-B2 (AU)
Title: Injection moulding apparatus
Inventor: SAYER MATTHEW EMMETT
IPC: B29C45/23
Filed: 1988-03-16
Granted: 1989-11-30
Abstract: Apparatus for producing an injection moulding of plastics material comprises means (18) for introducing a supply of plastics material (19) through one or more openings (43) in a mould space (13), and means (26, 34) for introducing a pressurised gas through a separate opening (44) in the mould space into the plastics material filling the mould space whereby the gas creates a gas containing cavity (25) in the plastics material and for thereafter relieving the gas pressure within the gas containing cavity before the mould is opened. The gas supply/pressure relieving means comprise at said separate opening (44) a valve port (42) opening directly into the mould space, a valve member (26) for opening and closing the valve port, and means (34) to supply pressurised gas to the mould space. The gas supply means are arranged to supply gas through the valve member (26) whilst the valve member is in a valve port closed position to create the cavity and after a moulding operation has been finished, the supply of pressurised gas can be terminated and pressurised gas in the cavity in the moulding can be vented to the atmosphere due to movement of the valve member to a valve port open position.
Patent AU-765492-B2 (AU)
Title: Aminopyrazole derivatives
Inventor: MINAMI NOBUYOSHI
IPC: A61P43/00
Filed: 1999-12-21
Granted: 2003-09-18
Abstract: <CHEM>   Aminopyrazole derivatives represented by formula (I), or salts thereof, wherein X<1> and X<2> are each a hydrogen atom or a halogen atom, or X<1> and X<2> may be united together to form a lower alkylenedioxy group, Q is a pyridyl group or a quinolyl group, R<1> is a hydrogen atom, a substituted or unsubstituted lower alkyl or aryl group, R<2> is a hydrogen atom, a lower alkyl group, or an aralkyl group, and R<3> represents a hydrogen atom, an organic sulfonyl group, or -C(=Y)-R<4> in which R<4> is a hydrogen atom or an organic residue and Y is an oxygen or sulfur atom, provided that, when R<3> is a hydrogen atom, R<1> is a group other than a hydrogen atom and R<2> is a hydrogen atom. These aminopyrazole derivatives or their salts have excellent p38MAP kinase inhibiting activities and are hence useful in the prevention or treatment of diseases associated with tumor necrosis factor  alpha , interleukin 1, interleukin 6 or cyclooxygenase II.
Patent AU-680731-B2 (AU)
Title: New pharmaceutical dosage form for transdermal administration
Inventor: LAURENT PHILIPPE
IPC: A61P17/00
Filed: 1995-04-28
Granted: 1997-08-07
Abstract: Compsn. designed to form a film on the skin for transdermal admin. of an active agent, comprises: a) a lipophilic active agent, b) 5-60 wt.% of a silicone-based adhesive polymer compsn. c) 0-25 wt.% of an absorption promoter, and d) 25-95 wt.% of a volatile solvent.
Patent AU-594299-B2 (AU)
Title: Process for nitrogen oxides reduction and minimization of the production of other pollutants
Inventor: EPPERLY WILLIAM ROBERT
IPC: C01B21/00
Filed: 1988-05-04
Granted: 1990-03-01
Abstract: A process for the reduction of nitrogen oxides in an effluent from the combustion of a carbonaceous fuel while minimizing the production of other pollutants is presented. The process comprises introducing (most commonly by injecting) a nitrogen oxides reducing treatment agent into an effluent according to a nitrogen oxides reducing treatment regimen under conditions such that the treatment agent is operating on the high temperature or right side of its nitrogen oxides reduction versus effluent temperature curve, especially on the high temperature or right side of the curve plateau.
Patent AU-593169-B2 (AU)
Title: A method for producing bread from preserved dough
Inventor: KAGEYAMA MINORU
IPC: A21C3/02
Filed: 1988-06-30
Granted: 1990-02-01
Abstract: A method of producing frozen dough for baking or frying to form bread comprises stretching the dough on a series of conveyors (1,2,3) while subjecting it to vibrations by means of rollers (5) so that the dough can be stretched without imparting pressure exceeding the yield point of its elasticity. Thus the gluten network structure is unharmed. Then the dough is frozen for preserving, and after a desired period of preservation the dough may be baked. By avoiding damage to the gluten network structure, the dough deflates less than conventionally treated dough during freezing and expands mo during the baking step, so that puffy and tasty bread results.
Patent AU-739444-B2 (AU)
Title: Strain regulating fusion cage for spinal fusion surgery
Inventor: BRESINA STEPHEN J
IPC: A61F2/30
Filed: 1998-10-20
Granted: 2001-10-11
Abstract: An intervertebral fusion cage for insertion between two adjacent, opposing vertebrae, wherein the fusion cage is constructed in a way that stress absorbed by the cage is transferred to the graft material in the hollow inner cavity, thus allowing ideal strain levels to be attained in the graft material under minimal loads, while also offering a level of protection to the graft material preventing mechanical failure of the graft material due to high strains.
Patent AU-562582-B2 (AU)
Title: Frame, in particular for a shower partition
Inventor: BAUS HEINZ GEORG
IPC: E06B3/964
Filed: 1983-12-05
Granted: 1987-06-11
Abstract: The invention relates to a frame, more particularly for a shower partition, the said frame comprising at least two shaped or profiled rails preferably connected together at a right angle. In the case of a frame of this kind, problems arise in the corner area in that the surfaces of the profiled rail, shaping element, covering profile, or the like in that area must be carried over into each other. Moreover, as a result of assembly inaccuracies, when a frame of this kind is assembled, gaps arise into which dirt can penetrate and which are also constructionally undesirable. It is therefore proposed, according to the invention, that a facing element (16) be arranged in the connecting area between the profiled rails (2, 4) on the outside of the frame, the said facing element comprising at least one spring locking means (36, 58). This spring locking means engages and/or catches in an opening (30, 36) in the profiled rail (4), thus ensuring an easily produced but functionally reliable attachment of the said facing element (16) to the profiled rail (4).
Patent AU-765909-B2 (AU)
Title: Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings
Inventor: DONG LIANG C
IPC: A61K9/52
Filed: 1999-12-10
Granted: 2003-10-02
Abstract: A dosage form comprising a gelatin capsule formed with a composite wall and containing a liquid, active agent formulation where the wall comprises a barrier layer formed over the external surface of the gelatin capsule, an expandable layer formed over the barrier layer and a semipermeable layer formed over the expandable layer is described. The dosage forms and methods provide for the conversion of standard gelatin, liquid formulation capsules into controlled, release dosage forms that permit the controlled release of the active agent into the environment of use over time.
Patent AU-671595-B2 (AU)
Title: Production of polyalkanoate
Inventor: LIEBERGESELL MATTHIAS
IPC: C12N15/52
Filed: 1992-07-15
Granted: 1996-09-05
Abstract: Genes encoding polyhydroxyalkanoate synthase, beta-ketothiolase and acetoacetyl CoA reductase are isolated from the publicly available bacterium Chromatium vinosum. Recombinant genomes of plants or other species of bacteria which contain these genes are capable of producing polyalkanoate polymers. The nucleotide sequences of the said three genees have been determined.
Patent AU-690679-B2 (AU)
Title: Transport vehicle for track sections
Inventor: THEURER JOSEF
IPC: E01B29/02
Filed: 1995-05-09
Granted: 1998-04-30
Abstract: The unit (1) has a lifting device (3) with a support frame (13) with height-adjustable support members (19). The support frame, by pairs of lift pistons (15) distanced from one another in the track longitudinal direction, is supportable on the track body and is height-adjustable in relation to it by a drive (18). A transport wagon (2) independently mobile from the lifting device at its end side has a rail undercarriage and a height-adjustable undercarriage unbound to the rails. Both the transport wagon has a link point between the end under carriages and the support frame has a link point. <IMAGE>
Patent AU-782858-B2 (AU)
Title: Pyrazine based inhibitors of glycogen synthase kinase 3
Inventor: NUSS JOHN M
IPC: A61P3/04
Filed: 2000-12-14
Granted: 2005-09-01
Abstract: New bicyclic based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combination with other pharmacologically active agents in the treatment of disorders mediated by GSK3 activity, such as in the treatment of diabetes, Alzheimer's disease and other neurodegenerative disorders, obesity, atherosclerotic cardiovascular disease, essential hypertension, polycystic ovary syndrome, syndrome X, ischemia, traumatic brain injury, bipolar disorder, immunodeficiency or cancer.
Patent AU-747036-B2 (AU)
Title: Self-enclosing heat exchangers with shim plate
Inventor: WU ALAN K
IPC: F28F3/02
Filed: 2000-02-04
Granted: 2002-05-09
Abstract: Self-enclosing heat exchangers are made from stacked plates having raised peripheral flanges on one side of the plates and continuous peripheral ridges on the other side of the plates, so that when the plates are put together, fully enclosed alternating flow channels are provided between the plates. The plates have raised bosses defining fluid ports that line-up in the stacked plates to form manifolds for the flow of heat exchange fluids through alternate plates. Expanded metal turbulizers are located in the flow channels. The turbulizers have portions thereof crimped closed to control the flow inside the channels and prevent unwanted bypass flow.
Patent AU-567262-B2 (AU)
Title: Reduction of the travel noise of tyres
Inventor: CAMPOS FRANCIS
IPC: B60C11/00
Filed: 1984-03-02
Granted: 1987-11-12
Abstract: A tire which emits reduced travel noise, when moving on a surface, having a tread formed of load-bearing elements distributed over the circumference of the tire in accordance with a plurality of repetitive design cycles of variable pitch is characterized by the fact that the number of each of the principal design cycles of different pitch satisfies all of the n-1 general relationships (B): <IMAGE>   and by the fact that the number of each of the design cycles present on the tread satisfies the relationship (C):   <IMAGE> it being understood that   <IMAGE>  and/or  epsilon  may each be equal to zero.
Patent AU-565523-B2 (AU)
Title: Heat pump having rotating plate heat exchangers
Inventor: CROSS WILLIAM TELFORD
IPC: F25B3/00
Filed: 1984-03-16
Granted: 1987-09-17
Abstract: A vapour compression heat pump is described which comprises an evaporator, a compressor and a condenser and in which at least the evaporator or the condenser is in the form of one or more rotatable plates across the thickness of which plate(s) a heat transfer takes place. Such a heat pump can be designed in compact form.
Patent AU-717870-B2 (AU)
Title: System and apparatus for smart card personalization
Inventor: TUSHIE DAVID R
IPC: G06Q20/36
Filed: 1997-04-14
Granted: 2000-04-06
Abstract: A smart card personalization system maintains a database containing card issuer data format templates, card applications, card operating system commands, and personalization equipment specifications and provides a centralized interface of inputs and outputs to a card issuing process which dynamically adjusts to changes in the issuing process to easily permit a card issuer to change data formats, card applications, card operating systems and/or personalization equipment in a card issuing process. The system interfaces to any card issuer management system, manages the transfer of cardholder data and card applications to the particular personalization equipment used, and maintains statistics for real-time and off-line inquiries to support critical management and reporting functions. Furthermore, the system works with a variety of security methodologies to prevent fraud.
Patent AU-702888-B2 (AU)
Title: Process to produce sanitary napkins with low tolerance between crimped side seal and absorbent core
Inventor: BITOWFT BRUCE KEVIN
IPC: A61F13/15
Filed: 1995-06-07
Granted: 1999-03-11
Abstract: The invention relates to a process for making a sanitary napkin having an absorbent core between a topsheet and a backsheet and a crimped side seal combining the topsheet and the backsheet around the core. In particular the process relates to making a product which has a small or no distance between the core and the crimped side seal of a sanitary napkin, by calandering the core to its final shape after the sides have been sealed together.