baber/WOPTO huggingface dataset:
Patent EP-0330026-B1 (EP)
Inventor: GOTO GIICHI
IPC: C07D409/12
Filed: 1989-02-11
Granted: 1994-10-05
Abstract: The present invention relates to unsaturated carboxylic acid amide derivatives of the formula <CHEM> wherein ring A stands for an optionally substituted aromatic ring; R<1> stands for a hydrogen atom or an optionally substituted hydrocarbon residue or forms an optionally substituted carbocyclic ring with the adjacent group -CH=C- together with two carbon atoms constituting the ring A; R<2> stands for a hydrogen atom, an optionally substituted hydrocarbon residue or an optionally substituted acyl group; R<3> stands for an optionally substituted hydrocarbon residue; and n denotes an integer ranging from 2 to 6, and salts thereof, as well as the production thereof. The compounds of the present invention act on the central nervous system of mammals and has a strong anti-cholinesterase activity, which can be used for the prophylaxis and therapy of, for example, senile dementia, Alzheimer's diseases, Huntington's chorea, et., and are useful as medicines.
Patent EP-0348777-B1 (EP)
Inventor: ONDERKA BERND
IPC: B21B37/48
Filed: 1989-06-19
Granted: 1994-08-24
Abstract: When rolling sections in universal stands of continuously operating section rolling mill trains, it has been found that changes in the speed ratios between the horizontal rolls and the vertical rolls lead to undesired material flow changes. As a result of the horizontal roll speed, the deformation in the section parts, the resulting transverse flow and the external forces at the roll gap, a certain speed is produced in the vertical rolls in proportion to the horizontal roll speed. Any change of the edge conditions of the rolling process leads to a change of the speed ratios between horizontal and vertical rolls. In order to eliminate these disadvantages, it is proposed to control the speed of the vertical rolls of the universal stands to influence optimally the horizontal roll speed and the vertical roll speed via a control device and to obtain a minimal pull between stands via a further control.
Patent EP-0365964-B1 (EP)
Title: Jet pipe
IPC: F04F5/12
Filed: 1989-10-16
Granted: 1992-08-05
Abstract: Jet pipes of this type are used in particular for processing contaminated earth. High costs for the exchangeable parts result from wear and the period of inoperation. The object is to design the jet pipe in such a way that the periods of inoperation are reduced and the wear lessened. The jet pipe (1) has an inlet (2), a section (3) adjoining the latter and having outlet openings arranged about the inside of the tube in the circumferential direction, and a conical tube section (5) adjoining the section (3). The conical tube section (5) is designed as a tube insert which can be inserted separately from the section (3). <IMAGE>
Patent EP-0374226-B1 (EP)
IPC: B23C5/02
Filed: 1989-06-05
Granted: 1993-04-21
Abstract: In a milling cutter for milling operations with a setting angle of preferably 90°, the face cutting edges (1a, 2a) and the hobbing cutting edges (1, 2) are set in opposite directions for chip removal. The hobbing cutting edges (1, 2) operating in each milling direction occupy half the width of the whole milling cutter, which can therefore be used as a reversing milling cutter.
Patent EP-0406857-B1 (EP)
Inventor: FUJISAWA YUKIO
IPC: C12N1/21
Filed: 1990-07-05
Granted: 1995-05-24
Abstract: Disclosed are (1) a fused protein obtained by combining an antigen used for vaccine and a lymphokine by the application of gene engineering, (2) a recombinant DNA containing a nucleotide sequence coding for the above fused protein, (3) a transformant bearing the above recombinant DNA, (4) a method for producing the fused protein which comprises cultivating the above transformant, producing and accumulating the above fused protein in a culture, and collecting the fused protein, and (5) a hybrid protein obtained by chemically combining an antigen used for vaccine with a lymphokine. The resulting fused and hybrid proteins have strong immunogenicity.
Patent EP-0421557-B1 (EP)
Title: Method and apparatus for indirect and external adjustment of the setting pressure of a shunt valve
Inventor: HAKIM SALOMON DR MED
IPC: H02K37/14
Filed: 1984-07-23
Granted: 1993-09-29
Abstract: The described surgically-implantable device has a stepping motor that can be isolated physically from electrical power sources and powered by the influence of a magnetic field applied from outside the body. The stepping motor includes a rotor and one or more stator elements, the stator elements being composed of magnetically soft and permeable material shaped and positioned with respect to the rotor so that when magnetized under the influence of the external field the stator elements strengthen and orient the magnetic field in their vicinities so as to cause movement of the rotor. The stepping motor may be used in a surgically-implantable shunt valve in which the popping pressure is adjusted in finite increments by application of the external magnetic field.
Patent EP-0378445-B1 (EP)
Inventor: BALLONI RICARDO
IPC: B32B27/18
Filed: 1990-01-15
Granted: 1998-05-27
Abstract: A polymer film laminate is provided having improved machinability on modern high speed belt drive machines, particularly when these machines are set up to form lap back seals. A method of assembling such a film is also provided. The film includes an outside web having an upper surface layer containing a silicone oil. This laminating web can be used with virtually any co-laminate, metallised or not, which is bonded thereto with an adhesive. Upon winding the composite film laminate upon a core, silicone oil is transferred to the inside surface of the laminate, thus providing an inside coefficient friction which is about equal to or less than the outside coefficient of friction. Hot slip properties are also improved upon such transfer. The outside and inside webs are independently formed, which allows the inside web to include coatings or film layers which are not ordinarily usable in a silicone oil-containing film.
Patent EP-0430401-B1 (EP)
Inventor: ZIEGENHAIN WILLIAM C
IPC: C01B7/19
Filed: 1990-08-03
Granted: 1994-04-27
Abstract: A process for preparing hydrogen fluoride involving treating anhydrous hydrogen fluoride containing primarily trivalent arsenic impurities with an effective amount of chromium (VI) oxide (i.e., CrO3) and oxygen such as to oxidize substantially all of the trivalent arsenic to pentavalent arsenic (i.e., As<+><3> ---> As<+><5>) followed by separation and recovery (e.g., by distillation) of purified anhydrous hydrogen fluoride.
Patent EP-0434373-B1 (EP)
Inventor: LOSONCZI ZOLTAN
IPC: H01K1/24
Filed: 1990-12-18
Granted: 1994-10-26
Abstract: In an internal current conductor for halogen filled incandescent lamps at least two spiralized members (1, 2) and an elongated part (3) forming a series assembly (4) are applied, wherein the series assembly (4) is at least partly made of a wire of lower electric resistance than that of the wire of the incandescent body. In a halogen-filled incandescent lamp, comprising a curved tube enclosure (5) made of a translucent material and enclosing a gas filling, an incandescent body (6) made by spiralization from a tungsten wire of circular cross-section, the incandescent body (6) being arranged within the enclosure (5), means for energizing (8, 9) the incandescent body (6) and two inside current conductors (4) for connecting the incandescent body with the energizing means (8, 9). Each internal current conductor consists of a first and a second spiralized member (1, 2) and an elongated part (3) forming together a series assembly (4), the series assembly (4) being connected via the second spiralized member (2) with the incandescent body (6) and via the first spiralized member (1) with the energizing means (8, 9), the series assembly (4) being at least partly made of a wire having cross-sectional area exceeding that of the tungsten wire forming the incandescent body (6). <IMAGE>
Patent EP-0390691-B1 (EP)
Title: Support wheel for reversible plough, for work and for transport
IPC: A01B15/00
Filed: 1990-03-29
Granted: 1992-09-02
Abstract: The wheeled support for a reversible plough comprises an arm (17) lockable in the working position vertically by means of an automatic system. This support has a pivot axis (11) arranged in the mid-plane of the frame of the plough perpendicular to the direction of advance, and a first operating axis (25) intersecting and perpendicular to said axis (11) in the working position. Between this axis (25) and the axis (11) is a second operating axis (13) which makes it possible to move the wheel a quarter turn to cause it to pass into the normal transport position. To obtain sufficient clearance of the wheel, the second operating axis (13) can be inclined relative to the first operating axis (25). <IMAGE>
Patent EP-0460032-B1 (EP)
Inventor: CALVERLEY MARTIN JOHN
IPC: A61P11/00
Filed: 1990-02-13
Granted: 1994-04-27
Abstract: The present invention relates to compounds of formula (I), in which formula R stands for an alkyl group containing from 7 to 12 carbon atoms optionally substituted with a hydroxy group; and derivatives of the compounds of formula (I) in which one or more hydroxy groups have been transformed into -O-acyl or -O-glycosyl or phosphate ester groups, such masked groups being hydrolyzable in vivo, in pure form or in mixtures. The present compounds find use in both the human and veterinary practice in the treatment and prophylaxis of autoimmune diseases, including diabetes mellitus, hypertension, inflammatory diseases such as rheumatoid arthritis and asthma as well as diseases characterized by abnormal cell differentiation and/or cell proliferation, and/or imbalance in the immune system.
Patent EP-0469071-B1 (EP)
Inventor: GAMOW RUSTEM IGOR
IPC: A61G10/02
Filed: 1990-04-20
Granted: 1995-10-11
Abstract: Une bulle hyperbarique portable améliorée (10) de montage est conçue pour être utilisée en haute altitude pour prévenir le mal des hauteurs et comprend une chambre portable fermée hermétiquement (10) dans laquelle un patient (80) peut être placé. Cette bulle est équipée avec une alimentation en oxygène (20) et des moyens de chasse du CO2, ou d'une vessie (50) pour éliminer le besoin de pomper constamment. La pression à l'intérieur de la chambre (10) est augmentée créant ainsi un environnement intérieur équivalent à une descente d'une haute altitude jusqu'à aussi bas que le niveau de la mer, dans le but d'atténuer le symptôme du mal des hauteurs. Dans un autre mode de réalisation, la bulle de montage est agrandie pour réaliser un habitat en haute altitude approprié pour être utilisé comme une tente de montagne.
Patent EP-0494212-B1 (EP)
Title: Coolant containment apparatus for rolling mills
IPC: B21B27/10
Filed: 1990-10-05
Granted: 1993-09-15
Abstract: Coolant containment apparatus for a rolling mill in which aqueous coolant liquid is sprayed onto the upper and lower work roll (11, 12 respectively) surfaces by upper and lower spray heads (24, 28 respectively) only on the exit side of the mill, including an enclosure (32) maintained at subatmospheric pressure and surrounding the upper spray head (24) and adjacent upper work roll (11) and backup rool (10) surfaces, upper and lower air dam members (40, 42 respectively) extending along the edges of the enclosure (32) above and below the spray head to define narrow air gaps at the roll surfaces, slippers (44) connected to ends of the dam members and in rubbing contact with the rolls to maintain the gap widths constant, and seal members (48) mounted on the roll supports (15) at the ends of the mill and cooperating with the enclosure to confine the enclosure interior. A wiper (50) removes coolant liquid from the upper work roll on the entry side of the mill, while collectors (52) catch and remove coolant spraying through the ends of the roll bite (18) at the exit side of the mill, and air is blown into the roll bite on the exit side to move coolant liquid from the surface of an emerging rolled metal strip (20) into the collectors. Below the mill pass line, a shield (58) protects the rolled metal strip from coolant from the lower spray head (28).
Patent EP-0450562-B1 (EP)
Inventor: CARTER MICHAEL CURTIS
IPC: C01B21/06
Filed: 1991-04-02
Granted: 1996-05-29
Abstract: A method and apparatus are provided for producing a product comprising a nitride compound, such as for example silicon nitride. A reactor (10) is provided which has a chamber (12) defined therein which is divided into a combustion zone (12a) and a reaction zone (12b). A combustible mixture is injected (48a,b,c) into the combustion zone in a direction generally toward the reaction zone, and is accordingly combusted in the combustion zone. At least one reactant is injected (56) at the boundary between the zones into the reactor chamber in a direction generally parallel to the longitudinal axis (14) of the chamber (12) so as to react to form raw product comprising the nitride compound. According to another aspect, a raw product powder as produced by the reactor comprises silicon nitride as the nitride compound and further comprises elemental silicon.
Patent EP-0453903-B1 (EP)
Inventor: HAUG PETER
IPC: B29C65/78
Filed: 1991-04-12
Granted: 1994-11-02
Abstract: Two plastic components, partic. pipes, are held coaxially in a jig for butt-welding. The component ends are heated without contact by an electrically heated plate (13) which has a ceramic coating (14). The plate (13) can be of copper or steel and have several cartridge heaters (15) and a temperature sensor (16). The thickness of the ceramic coating (14) can be 0.1-0.6 mm. There can be a thin layer of Ni between a Cu plate (13) and the ceramic coating (14). Pref. a frame (3) has a fixed clamp (4) holding a pipe (1) and a movable clamp (5) for a component (2) which is brought into the required position. The heating arrangement (7) can be swung into position with a handle (9) on a spring loaded lever (8). The heater (12) has stops (17) which allow it to be lined up accurately. A gauge (19) and cutter (20) are used to machine the required weld preparation.
Patent EP-0467070-B1 (EP)
Inventor: PALM ERICH
IPC: F16B31/02
Filed: 1991-06-12
Granted: 1994-12-14
Abstract: It is intended to mount sealing webs (2) directly into a support (10) with a low pull-out resistance, for example into aerated concrete, using a screw consisting of a shank (1) and a screw head (4). A washer (3) is inserted under the screw head (4). Constructed on the circumferential region of the screw head (4) is a profiling in the form of a milled edge (6), which considerably increases the insertion torque of the screw and, in the directly final screwing-in section, digs into the countersink opening of the washer (3), which cannot rotate as a result of friction and/or force-locking, and thus considerably increases the torque. As a result of this increase in torque as the screw is screwed in, the torque coupling of a screwdriver is initiated, thus preventing overrotation of the shank (1) which is provided with a coarse thread pitch. <IMAGE>
Patent EP-0512152-B1 (EP)
Inventor: JAEGER ROLF
IPC: B67D1/08
Filed: 1991-07-13
Granted: 1995-10-11
Abstract: Safety devices exist for insertion into an outlet opening of a pressurised beverage cask, in particular a beer cask, having a housing (5), a central tube (15), a bayonet plate (11), which engages with outer projections in L-slits of a housing part, and also having a compression spring (21), which is supported on the one hand against the bayonet plate and on the other hand against a sealing device (20). In order to make the safety device possible in completely fitted-together form by simple pushing into the outlet opening of the beverage cask and by simple screwing-in, it is proposed to provide at least one movable locking element (22) which is designed and arranged in such a way that, during the insertion operation, it can give way with respect to the edge of the outlet opening and, in the operating position, engages behind the inner edge of the outlet opening. <IMAGE>
Patent EP-0476511-B1 (EP)
Inventor: YAMADA TOSHIYUKI
IPC: F02B33/30
Filed: 1991-09-11
Granted: 1994-07-20
Abstract: A reed valve assembly (11) is mounted in a valve chamber (10) formed in an intake passage of a crankcase (2) of a two-stroke cycle engine and the reed valve assembly (11) comprises a box-shaped valve body (12) having a base end opened and secured to an intake pipe (9) and a front end converging towards the crankcase (2), the valve body (12) being provided with valve openings (13) formed to side surfaces of the valve body (12), and reed valves (14) resiliently provided for the valve openings (13). The valve chamber (10) has opposing inner wall surfaces (10a) gently curved outwardly for forming expanded portions between the side surfaces of the valve body and the expanded surfaces (17) of the valve chamber. The curved surfaces of the inner wall surfaces of the valve body converge towards an interior of the crankcase with an inclination of about 10 to 20 degrees and a maximum lateral width of each of the expanded portions (17) is defined to about 5 to 10 mm. <IMAGE>
Patent EP-0454258-B1 (EP)
Inventor: RAATJES EGBERTUS SYBOLT
IPC: E01C11/22
Filed: 1991-04-23
Granted: 1993-12-29
Abstract: Metal edge section (1) or edge frame which has been anchored into a gutter or drain body for supporting lids or grids on a bearing surface to fix them within a confining plane, said lids or grids having been placed over drain gutters or drains, and for protection of the edges of said gutter or drain body. The anchorage comprises more or less trapezoidal cast-on protrusions (5) or ribs formed on a bottom flange plane (2a) of the edge section (1) and on an outer plane (4a) pertaining to the confining plane (4), wherein the protrusions or ribs have inclined planes (5a) positioned at an acute angle to the bottom flange plane (2a). <IMAGE>
Patent EP-0481676-B1 (EP)
Inventor: KULAGOWSKI JANUSZ J
IPC: A61P25/28
Filed: 1991-10-10
Granted: 1997-01-29
Abstract: A class of 4-hydroxy-2-(1H)-quinolone derivatives, substituted at the 3-position by an optionally substituted aryl substituent, are selective non-competitive antagonists of NMDA receptors and/or are antagonists of AMPA receptors, and are therefore of utility in the treatment of conditions, such as neurodegenerative disorders, convulsions or schizophrenia, which require the administration of an NMDA and/or AMPA receptor antagonist.
Patent EP-0540790-B1 (EP)
Inventor: MAMMARELLA CARLOS
IPC: C12N9/24
Filed: 1991-11-05
Granted: 1996-09-11
Abstract: A method of obtaining monosialoganglioside (GM1) from an aqueous solution containing a mixture of gangliosides, involves incubating the solution at a pH of from 5 to 6.5 in the presence of an neuroaminidase so as to hydrolyse di-, tri- and tetra- sialogangliosides therein to enrich the GM1 content of the mixture. The resultant solution is dried, the residue re-dissolved in a mixture of chloroform, methanol and water and is then subjected to exclusion chromatography. The appropriate fractions are collected and lyophilized.
Patent EP-0544040-B1 (EP)
Inventor: MOSSER MARK F
IPC: B32B15/08
Filed: 1991-11-28
Granted: 1996-09-11
Abstract: A coated article (10) and method of making the same is disclosed wherein the coated article (10) includes a substrate (12) consisting essentially of titanium or titanium alloy and an outer coating (14) of thermoplastic resin for protecting the substrate from chemical degradation and maintaining stability during exposure to temperatures of at least up to 260 DEG C. An adhesion primer layer (16) is disposed between the substrate (12) and the outer coating (14). The adhesion primer layer (16) includes an inorganic binder matrix for increasing adhesion to the titanium and titanium alloys. The primer layer (16) further includes a thermoplastic resin in particulate form for increasing adhesion to the outer coating (14).
Patent EP-0502975-B1 (EP)
Inventor: WADHWA VIVEK K
IPC: G06F9/44
Filed: 1990-11-30
Granted: 1997-07-16
Abstract: A computer-aided software engineering facility and method for creating computer source code and executable computer programs that are distributable across multiple hardware environments or platforms. An object oriented modeling system is linked with modules of a computer programming language and other system components to quickly and efficiently design computer source code and executable computer modules that have a high degree of reusability. The modules and models are stored in a centralized storage area and distributed to the various hardware elements that comprise the computer system.
Patent EP-0531396-B1 (EP)
Inventor: BRANEMARK PER-INGVAR
IPC: A61C8/00
Filed: 1991-05-16
Granted: 1995-04-19
Abstract: PCT No. PCT/SE91/00348 Sec. 371 Date May 21, 1992 Sec. 102(e) Date May 21, 1992 PCT Filed May 16, 1991 PCT Pub. No. WO91/18556 PCT Pub. Date Dec. 12, 1991.A fixture intended to be implanted into bone tissue, for example, the bone tissue of a jaw, for anchoring a prothesis, such as a tooth crown. The fixture includes a cylindrical head disposed on the end of a shaft for positionally fixing the prothesis. An upper and lower external thread section is formed on the shaft. The lower external thread section is screwed into a previously prepared hole in the bone tissue, the hole having a diameter that is substantially equal to a core diameter of the shaft. A thread-free zone is located along a mid-section of the shaft. The thread-free zone has a smooth outer surface to avoid the irritation of nerves present in the bone tissue in the vicinity of the fixture. Gently curving transitional portions connect the thread-free zone with the upper and lower external thread sections. The thread-free mid-section and the lower external thread section are provided with a coating of tissue friendly material.
Patent EP-0597847-B1 (EP)
Inventor: KAY M
IPC: C07K14/705
Filed: 1991-05-24
Granted: 1999-09-01
Abstract: Disclosed herein is a synthetic senescent cell antigen comprised of purified peptides immunoreactive with antibodies to the naturally occurring antigen. Preferably, the synthetic senescent cell antigen comprises two peptides with the amino acid sequences SKLIKIFQDHPLQKTYN and LFKPPKYHPDVPYVKR, respectively. The antigen and peptides may be used in compositions, diagnostic kits, and methods for detecting or measuring antibodies to senescent cell antigen, studying cellular aging and autoimmune mechanisms, separating anions from a gas or liquid, or treating certain diseases.
Patent EP-0592415-B1 (EP)
Inventor: BERGLUND SVANTE
IPC: F16K/
Filed: 1991-06-20
Granted: 1996-03-27
Abstract: A valve arrangement comprises a valve housing (4) which has a valve chamber (7, 13, 15) with an outlet (9, 10, 11, 12) and an inlet (16) which is adapted to be connected to a pressure-medium source (25), and a valve opening communicating with the valve chamber. A control valve (8, 22) is mounted on the valve housing (4) to close the outlet of the valve chamber when in closed position, and open this outlet when in open position. A main valve (14, 17) mounted on the valve housing (4) has, in the valve opening, a valve member (17) which is movable in response to the pressure in the valve chamber (7, 13, 15) between an outer closing position and an inner opening position. The inlet (16) of the valve chamber extends through the wall of the valve housing (4).
Patent EP-0536226-B1 (EP)
Inventor: CLARK ROSS G
IPC: A61K47/10
Filed: 1991-05-31
Granted: 1996-08-28
Abstract: PCT No. PCT/US93/10259 Sec. 371 Date Nov. 19, 1993 Sec. 102(e) Date Nov. 19, 1993 PCT Filed Oct. 26, 1993 PCT Pub. No. WO91/18621 PCT Pub. Date Dec. 12, 1991A method is disclosed for treating obese mammals or preventing obesity from occurring in mammals. This method involves administering to the mammal an effective amount of growth hormone in combination with an effective amount of IGF-I. Preferably, the growth hormone is given so as to have a maintained, continual therapeutically effective presence in the blood, such as by continuous infusion or frequent injections, or by use of a long-acting formulation.