baber/WOPTO huggingface dataset:
Patent WO-2006099021-A9 (WO)
Title: Inversion directe de la fonction inhibitrice des lymphocytes t regulateurs de cd4+ via la signalisation du recepteur 8 de type toll
Inventor: WANG RONG-FU
IPC: A61K48/00
Filed: 2006-03-09
Abstract: L'invention concerne les lymphocytes T régulateurs de CD4+ (Treg) qui inhibent profondément les réponses immunitaires d'un hôte et protègent ainsi contre les maladies auto-immunes tout en restreignant les réponses immunitaires désirées, telles que l'immunité antitumeur. Des oligonucléotides protégés par un phosphorothioate synthétique et contenant une guanosine peuvent inverser directement l'activité inhibitrice des lymphocytes Treg sans impliquer de cellules dendritiques. Cet effet donne l'impression d'être transduit par signalisation via le récepteur 8 de typeToll (TLR) et l'engagement des molécules MyD88 et IRAK4 dans des lymphocytes Treg. La stimulation des lymphocytes Trek à l'aide de ligands naturels pour TLR8 humains reprend l'effet des oligonucléotides contenant une guanosine synthétique.
Patent WO-2008010788-A9 (WO)
Title: Compositions et procédés de fabrication et d'utilisation de nanoémulsions
Inventor: NICOLOSI ROBERT
IPC: A23L33/00
Filed: 2006-07-11
Abstract: La présente invention concerne une nanoémulsion améliorée comprenant une plage uniforme et discrète de très petits diamètres de particules de taille nanométrique. Cette uniformité entraîne une meilleure biodisponibilité des composés incorporés (par exemple des produits pharmaceutiques ou des produits nutraceutiques) telle que reflétée par différents paramètres pharmacocinétiques dont, mais ils ne sont pas limités à ceux-ci, un Tmax réduit, une Cmax réduite et une aire sous la courbe (AUC) réduite. Le procédé amélioré de fabrication de ces nanoémulsions uniformes utilise la microfluidisation qui diffère à la fois en termes de procédé et de mécanique par rapport aux techniques de pulvérisation et de meulage classiques utilisées pour générer des compositions de nanoparticules. En outre, l'amélioration résulte, en partie, d'une nouvelle étape de mélange d'un composé pratiquement soluble dans un milieu de dispersion chauffé. Ceci est différent des procédés de fabrication de compositions de nanoparticules actuels qui mélangent un composé insoluble avec un milieu de dispersion non chauffé. En outre, on observe que ces nanoémulsions sont résistantes aux bactéries et stables vis-à-vis d'extrêmes à la fois en termes de variation de température et en termes de variation de pH. En conséquence, on s'attend à ce que ces nanoémulsions aient une durée de conservation considérablement allongée par rapport aux nanoémulsions actuellement disponibles.
Patent WO-2007087548-A9 (WO)
Title: Composés chimiques
Inventor: GUDMUNDSSON KRISTJAN
IPC: A61K31/4745
Filed: 2007-01-24
Abstract: La présente invention concerne des composés représentés par la formule (I), y compris des sels, des solvates, et des dérivés pharmaceutiquement acceptables desdits composés, des préparations pharmaceutiques les contenant, des procédés pour leur préparation, ainsi que des méthodes de traitement faisant appel auxdits composés.
Patent WO-2010011751-A9 (WO)
Title: Motor arrangement for window coverings
Inventor: SKINNER GARY
IPC: A47H5/00
Filed: 2009-07-22
Abstract: The present invention relates to an architectural window covering having a programmable electric motor. The programmable electric motor is housed within a roller for raising and lowenng the window covering, and includes dual stacked motors and light-transmitting control actuation buttons In one embodiment an architectural window covering, composing a shade, a roller defining a bore coupled to the shade, and at least two motors axially aligned and electrically coupled in parallel and positioned at least partially in said bore and rotatably coupled to the roller is disclosed.
Patent WO-2016073982-A9 (WO)
Inventor: SPROUT EDWIN L
IPC: E21B19/083
Filed: 2015-11-09
Abstract: A support frame assembly comprises a base and an object support member having a first position and a second position. The support frame assembly may also include a plurality of pivot arms operatively connected to the base and the object support member. At least one of the pivot arms may have an actuator for moving the object support member form the first position to the second position. The support frame assembly may also include an adjustment member operatively connected to one of the plurality of pivot arms to adjust a position of the object support member relative to the base for self-alignment between an object such as a tubular member and a drill head.
Patent WO-2016086201-A9 (WO)
Title: End member assemblies as well as gas spring assemblies, suspension systems and methods including same
Inventor: BOUNDS JOSEPH A
IPC: F16F9/04
Filed: 2015-11-25
Abstract: An end member assembly can include a first end member section and a second end member section that together form an end member volume. A partition section is provided separately and is disposed within the end member volume to separate the end member volume into at least two volume portions. At least one passage extends through the partition section and at least one control device is disposed in fluid communication along the passage. The control device substantially fluidically isolates the two volume portions under conditions of use below a predetermined differential pressure threshold. The control device permits fluid communication between the two volume portions under conditions of use in which the predetermined pressure threshold is exceeded. Gas spring assemblies including such an end member assembly as well as suspension systems and methods of manufacture are also included.
Patent WO-2017177025-A9 (WO)
Title: Compositions, procédés, et kits pour la synthèse et la détection d'acides nucléiques
Inventor: LE FERRIER
IPC: C12Q1/68
Filed: 2017-04-06
Abstract: L'invention concerne des compositions, des procédés et des kits pour la synthèse, la détection, et/ou la quantification d'acides nucléiques. Des modes de réalisation comprennent une composition d'amplification d'acides nucléiques comprenant une ADN polymérase thermostable et des agents qui améliorent la synthèse des acides nucléiques, l'amplification, la détection et/ou la quantification d'acides nucléiques cibles dans un échantillon de type extrait brut ou lysat brut.
Patent WO-2020123318-A9 (WO)
Title: Resolving spatial arrays using deconvolution
Inventor: FRENZ LUCAS
IPC: C12Q1/6837
Filed: 2019-12-06
Abstract: Methods for determining a location of a feature on an array include: (a) providing a first array with a first plurality of features immobilized on a first substrate; (b) providing a second array with a second plurality of features immobilized on a second substrate; (c) aligning the first array with the second array; (d) hybridizing a first barcoded oligonucleotide of the first array to a second barcoded oligonucleotide of the second array, thereby producing a combined nucleic acid that includes first and second spatial barcodes; (e) determining all or a portion of the sequence of the combined nucleic acid; and (f) identifying the second barcoded oligonucleotide associated with the first barcoded oligonucleotide in the combined nucleic acid, and determining the location of a second feature in the second array.
Patent WO-2020214833-A9 (WO)
Inventor: LEDWITH ALEXANDER
IPC: H04W12/00
Filed: 2020-04-16
Abstract: In some embodiments, a first device performs ranging operations to allow a user to perform one or more operations on the first device without providing device-access credentials. For example, when a second device is within a first distance of the first device, the first device determines that the second device is associated with a first user account that is authorized to perform operations on the first device. In response to the determination, the first device enables at least one substitute interaction (e.g., a password-less UI interaction) to allow the operations to be performed on the first device to be accessed without receiving access credentials through a user interface. In response to detecting an occurrence of the substitute interaction, the operation is authorized on the first device.
Patent WO-2022125292-A9 (WO)
Title: Conveyor transfer system
Inventor: HALL BENSON
IPC: B65G54/02
Filed: 2021-11-19
Abstract: A transfer system comprising a carrier attached by fastening structure to a linear-motor shuttle driven by a linear-motor stator along a track. Tray packs or other conveyed objects are transferred between the carriers and infeed and outfeed conveyors by the carriers at transfer segments as the carriers advance along the track.
Patent WO-2022173634-A9 (WO)
Title: Methods and systems for accurate measurement of deep structures having distorted geometry
Inventor: HENCH JOHN
IPC: H01L21/66
Filed: 2022-02-02
Abstract: Methods and systems for estimating values of geometric parameters characterizing in-plane, distorted shapes of high aspect ratio semiconductor structures based on x-ray scatterometry measurements are presented herein. A parameterized geometric model captures the scattering signature of in-plane, non-elliptical distortions in hole shape. By increasing the number of independent parameters employed to describe the in-plane shape of hole structures the model fit to the actual shape of high aspect ratio structures is improved. In one aspect, a geometrically parameterized measurement model includes more than two degrees of freedom to characterize the in-plane shape of a measured structure. In some embodiments, the geometric model includes a closed curve having three degrees of freedom or more. In some embodiments, the geometric model includes a piecewise assembly of two or more conic sections. Independent geometric model parameters are expressed as functions of depth to capture shape variation through the structure.
Patent CS-219673-B1 (CS)
Inventor: KALAFUT STEFAN
IPC: C01G13/00
Filed: 1981-01-06
Abstract: Vynález sa týká získavania ortute z odpadových
vód, ktoré vznikajú pri pyrometalurgickej výrobě
ortute.
Problém odpadových vód z uvedenej výroby
spočívá v tom, že ortuť vo formě mikrokvapiek je
vo vodě jemne dispergovaná alebo okludovaná
v hydrofóbnej pene a sedimentáciou sa neodstraňuje.
Vyzrážanie iontovej ortute klasickými zrážadlami
vedie k tvorbě anorganických koloidov,
ktorých izolácia sposobuje ťažkosti alebo vzniká
nespracovatelný odpad. Tento problém podlá vynálezu
je riešený tak, že odpadové vody po
predbežnom čistění sedimentáciou sa prepúšťajú
cez vrstvu granulovanej aktívnej hmoty, výhodné
cez vrstvu aktívneho uhlia, ktoré je impregnované
vápnom, alkalickými sírnikmi alebo ich zmesou
v pomere 6:1a granulovaná aktívna hmota po
nasýtení ortuťou sa najprv volné vysuší pri teplote
10-30 °C a potom odpražuje na Hg pri teplote
500—650 °C. Na granulovanej aktívnej hmotě sa
súčasne vyzrážava iontová ortuť, sorbujú anorganické
koloidy obsahujúce mikrokvapky ortute
a filtruje tuhá a pěnová fáza s okludovanou
ortuťou. Filtrát, v případe, že obsahuje kysličník
siřičitý sa bežne zráža s vápnom a po vyčerpaní
voda sa vracia spáť do procesu.
Patent IE-35955-B1 (IE)
Title: Improvements in and relating to fluid administration devices
IPC: A61M5/24
Filed: 1972-01-04
Abstract: 1376843 Medicament injectors I M S Ltd 26 Jan 1972 [5 Oct 1971] 3613/72 Heading A5R A medicament injector comprises a fluid passage member 40 having a central bore 42 and extending lengthwise within a thrust portion 14 provided within a barrel 10 from which extends a urethral tip 59 communicating with the central bore 42. Means 50 is associated with the end of member 40 for puncturing a diaphragm sealing a central opening 32 in a rubber stopper 20 reciprocable within a vial 18 containing the medicament. The means 50 may be provided by a point on a tip 48 carried by member 40 and having openings 56 comunicating with the bore 42. A flange 58 on tip 48 maintains member 42 substantially concentric with respect to the thrust portion 14. The stopper 20 has a part 24 of reduced diameter adapted to be threaded into thrust portion 14. In a modification, the tip 48 is omitted, the puncturing means being provided by the end of member 40 which is bevelled and the flange 58 being integral with member 40.
[GB1376843A]
Patent IE-44056-B1 (IE)
Title: Diapers
IPC: A61F13/49
Filed: 1977-01-05
Abstract: 1527300 Diapers COLGATE-PALMOLIVE CO 31 Dec 1976 [5 Jan 1976] 54457/76 Heading A3V A disposable diaper comprises a first pad 36 in the crotch area and at least one other pad 38, 42 of hydrophilic absorbent material, the first pad being of a material (e.g. polyurethane or polyethylene foam) which has a greater wet resiliency than the other pad(s).
Patent IE-80145-B1 (IE)
Title: Interproximal brush
Inventor: ZIMMERMAN WALTER
IPC: A46B7/04
Filed: 1991-01-04
Abstract: An interproximal brush comprises a handle having an end portion provided with a transverse hole communicating with a longitudinal groove for receiving the elongated stem of an interproximal brush. The handle further has a cylindrical boss formed on the lower surface thereof through which the transverse hole extends, and the brush stem is retained securely in the longitudinal groove on closure of a cap, which is pivotably attached to the end portion.
Patent CS-208377-B1 (CS)
Inventor: DUDIK MIROSLAV
IPC: H01L21/04
Filed: 1978-02-08
Abstract: Vynález sa týká spósobu výroby rýchlych vysokonapaťových
usměrňovačích blokov so střednými
usměrněnými prúdmi od 2 do lOOmA.
Účelom vynálezu je vyriešiť spósob zníženia
zotavovacej doby usmemovača premožnosťvyužitia
vo vyšších pracovných teplotách.
Uvedeného účelu sa dosiahne zaradením vysokoteplotnej
difúznej operácie, pri ktorej potřebný
difuzant obsahuje platinu.
Vynález je možné využiťprivýrobě vysokonapáťových
polovodičových usměrňovačích prvkov.
Patent CS-214547-B1 (CS)
Inventor: HOLECI IVAN
IPC: B01J19/00
Filed: 1981-02-05
Abstract: Vynálpz se týká kontaktního zařízení pro
heterogenní systémy s otáčivou vrstvou tuhých
částic. Zařízení se skládá z válcovité
komory',, která je opatřená potrubím pro pří­
vod a odvod zpracovávaných fází a tryskami
pro přívod lehčí fáze a dále otáčivým
dnem, nad jehož střední částí je ukončeno
potrubí pro přívod kondenzované fáze. Na
tomto otáčivém dnu mohou být pevně uchyceny
kolíčky
Patent CS-215968-B1 (CS)
Inventor: MATES STEFAN
IPC: A61B5/02
Filed: 1981-02-11
Abstract: Přenosný lékařský tonometr je využíván
převážně ve zdravotnictví k nepřímému měření
krevního tlaku pacientů.
Předmět vynálezu řeší problém získání
zdroje tlaku plynu potřebného k nafouknutí
gumové manžety tonometru přiložené na
paži vyšetřovaného. Jako zdroje tlaku plynu
se využívá nádoby se stlačeným plynem,
který se regulačním ventilem vpouští přes
pojistný ventil, omezující tlak v systému
na nastavenou mez a výpustný ventil do
manžety
Patent CS-242333-B1 (CS)
Inventor: MICHALKA VLADIMIR
IPC: B65G47/86
Filed: 1985-02-12
Abstract: Očelom vynálezu je odstránenie zádržiek
dopravovaných súčiastok zo sklzu do pracovného
rotora.
Uvedeného účelu sa dosahuje zariadením
na dávkovanie válcových súčiastok do rotora
stroja podl'a vynálezu, ktorého podstata
spočívá v tom, že dávkovači kotúč je na obvode
opatřený unášačom zasahujúcim do odoberacieho
lůžka. Odoberacie lůžko je vytvořené
v kyvnom odpruženom telese, ktoré
je uložené na vodiacej lište. Na dávkovacom
kotúči je prostredníctvom držiaka uložený
odpružený segment zasahujúci do dráhy tretej
dopravovanej súčiastky.
Patent IE-38801-B1 (IE)
Title: 4-phenylpiperidine compounds
IPC: C07D317/46
Filed: 1974-01-29
Abstract: 1422263 4-Phenyl-piperidines FERROSAN AS 23 Jan 1974 [30 Jan 1973] 4496/73 Heading C2C Novel compounds (I) (including salts thereof) wherein R represents an alkyl or alkynyl group having 1-4 carbon atoms, or a phenyl group optionally substituted by C 1-4 alkyl, alkylthio, alkoxy, halogen, nitro, acylamino, methylsulphonyl or by methylenedioxy, or represents tetrahydronaphthyl, R<SP>1</SP> represents H, trifluoro (C 1-4 )alkyl, alkyl or alkynyl, and X represents hydrogen, alkyl having 1-4 carbon atoms, alkoxy, trifluoroalkyl, hydroxy, halogen, methyl thio or aralkoxy, are made from the corresponding -CH 2 OH compounds. The methane sulphonate of 3-hydroxymethyl-1-methyl-4-phenylpiperdine is also prepared. Pharmaceutical preparations useful as antidepressants and anti-Parkinson agents contain (1) as active ingredient.
[GB1422263A]
Patent IE-62878-B1 (IE)
Title: Hydrogen peroxide plasma sterilization system
Inventor: JACOBS PAUL TAYLOR
IPC: A61L2/14
Filed: 1988-01-26
Abstract: A sterilization process wherein articles contacted with hydrogen peroxide and containing trace amounts of residual hydrogen peroxide are subjected to plasma treatment to generate an active species from the residual hydrogen peroxide which effects sterilization of the article and concurrently removes the residual hydrogen peroxide by converting it into non-toxic decomposition products.
Patent IE-64493-B1 (IE)
Title: 9-amino-1,4-ethano-1,2,3,4-tetrahydroacridine and related compounds intermediates and a process for the preparation thereof and their use as medicaments
Inventor: SHUTSKE GREGORY MICHAEL
IPC: A61P25/28
Filed: 1988-02-12
Abstract: There are disclosed compounds having the formula wherein R is hydrogen, loweralkyl or loweralkylcarbonyl; R1 is hydrogen, loweralkyl, loweralkylcarbonyl, aryl, diloweralkylaminoloweralkyl, arylloweralkyl, diarylloweralkyl, oxygen-bridged arylloweralkyl or oxygen-bridged diarylloweralkyl; R2 and R3 are independently H or CH3; X is hydrogen, loweralkyl, cycloalkyl, loweralkoxy, halogen, hydroxy, nitro, trifluoromethyl, formyl, loweralkylcarbonyl, arylcarbonyl, -SH, loweralkylthio, -NHCOR4 or -NR5R6 where R4 is hydrogen or loweralkyl, and R5 and R6 are independently hydrogen, loweralkyl or cycloalkyl; Y and Z are independently a direct bond, CR7R8 or CR7R8-CR9R10; and P and Q are independently CR7'R8', CR7'R8'-CR9'R10' or CR7'R8'-CR9'R10'-CR11R12, where each of R7 through R12 and R7' through R10' is independently H or CH3; stereo, optical and geometrical isomers thereof, and pharmaceutically acceptable acid addition salts thereof, which are useful for enhancing memory.
Patent IE-52907-B1 (IE)
Title: Process for preparing 6-(d-(-)-alpha-(4-c1-c4-alkyl-2,3-dioxo-1-piperazinocarbonyl-amino)-phenylacetamido)-penicillanic
IPC: A61K31/43
Filed: 1982-03-29
Abstract: There is provided a process for preparing in high yields a 6-[D(-)- alpha-(4-C1-C4-alkyl-2,3-dioxo-1- piperazinocarbonylamino)- phenylacetamido]penicillanic acid, or pharmaceutically acceptable salt thereof, in which a 4-C1-C4-alkyl- 2,3-dioxo-1-piperazinocarbonyl halide is added under controlled pH conditions to a solution or suspension of ampicillin in a mixture of ethyl acetate and water in the presence of a base to form a reaction mixture, the resulting mixture is agitated until the reaction is completed, the reaction mixture is acidified, and the desired antibiotic is recovered as a crystalline product under controlled pH conditions and using controlled amounts of ethyl acetate as solvent.
Patent IE-58388-B1 (IE)
Title: 1,2-benzisoxazol -3-yl and 1,2-benzisothiazol-3-yl derivatives
IPC: A61K31/54
Filed: 1986-03-26
Abstract: Novel 3-piperidinyl-1,2-benzisothiazoles and 3-piperidinyl-1,2-benzisoxazoles having the formula wherein X is O or S and Q is a radical of formula or a radical of formula the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds have antipsychotic properties; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent IE-39453-B1 (IE)
Title: Improvements in and relating to a suspension system for operable partitions
IPC: E05D15/06
Filed: 1974-04-18
Abstract: A multidirectional suspension system for operable partitions comprising an overhead track defining a pair of vertically spaced rollerway defining ledges disposed on either side of the track, and carriers for suspending the partition panels from the track, with each carrier being in the form of a pendant bolt operating between the track ledges and having coaxially journaled thereon for rotation thereabout a pair of discs each defining a downwardly facing load support side surface, and with the load support side surfaces of one of the discs riding on one of the ledges free of contact of the other ledge, and the other disc load support side surface riding on the other of the ledges free of contact of the first ledge. The track can have cross-over intersections, T-intersections, and right angle and Y-turns for ready maneuvering of the panels as desired, and without the need for switches, with said ledges and guidance ledges opposing them engaging guidance elements on the carrier, to maintain the individual carriers properly centered when moved about intersections and turns.
[US3879799A]
Patent MA-31111-B1 (MA)
Inventor: CENS BERNARD
IPC: B62D65/18
Filed: 2009-07-23
Abstract: La présente invention concerne un dispositif de manutention (1) destiné à transporter un soubassement (100) d'au moins un type de véhicule automobile, le soubassement (100) étant constitué d'un assemblage de plusieurs éléments (110), (120, 130) sensiblement complémentaires. L'invention est remarquable en ce que le dispositif de manutention (1) comporte un support secondaire (20), apte à maintenir individuellement chaque élément (110, 120, 130) non assemblé du soubassement (100), et un support principal (10), sur lequel est monté amovible le support secondaire (20), lequel support principal (10) est apte à maintenir le soubassement complet 100 une fois ses différents éléments (110, 120, 130) assemblés sur le support secondaire (20) et une fois le support secondaire (20) retiré du support principal (10).
Patent MA-32449-B1 (MA)
Inventor: GURNEY AUSTIN L
IPC: A61K39/395
Filed: 2011-01-03
Abstract: يتعلق الاختراع بعوامل الربط نوتش notch ومناهضات نوتش إضافة إلى طرق استخدام عوامل و / أو مناهضات لعلاج أمراض مثل السرطان. نصف أجساما مضادة تُربط تحديدا بمنطقة ربط خارج رابط للمجال الخارج الخلوي لمستقبل أو لمستقبلات بشرية عديدة من صنف نوتش2 و/أو نوتش3 وتثبط نمو الورم.يتعلق الاختراع أيضا بطرق علاج السرطان، تتمثل في إعطاء كمية علاجية فعالة من أجسام مضادة ترتبط تحديدا بمنطقة ربط خارج رابط للمجال الخارج الخلوي لبروتين المستقبل البشري نوتش notch وتثبط نمو الورم.
Patent MA-33962-B1 (MA)
Title: Chaise lunettes
Inventor: ADIL BENAZZOUZ
IPC: A47C13/00
Filed: 2011-05-05
Abstract: Dispositif pour offrir une nouvelle manière de voir les sièges ainsi que de connaître un nouveau design.L'invention concerne de la sorte un dispositif permettant de connaître une nouvelle forme de sièges qui seront sous forme de lunettes et offriront une nouvelle forme de confort.Il est constitué de deux cercles ou autre qui auront pour but d'être les dossiers ainsi de deux sièges sous forme cylindrique ou autres et enfin d'accoudoirs qui finaliseront l'aspect lunette du siège.Le dispositif selon l'invention est particulièrement destiné à développer le concept de chaises new design et découvrir une nouvelle forme de confort.
Patent MA-46985-B1 (MA)
Title: Fenêtre de mesure de resélection de cellules dans une nouvelle radio
Inventor: RUNE JOHAN
IPC: H04W48/16
Filed: 2018-03-23
Abstract: L’invention concerne un nœud de réseau radio, de type gnodeb (gnb), un équipement d’utilisateur (ue) et un procédé, pour la configuration d’un ue campant sur une cellule desservie par le nœud de réseau radio pour des mesures de resélection de cellules sur la base de blocs de signaux de synchronisation (ss) pour des états rrc_idle et rrc_inactive. Le procédé consiste à transmettre des informations, de type informations de système (si), à l’ue, incluant des paramètres de configuration pour une fenêtre de mesure, les paramètres de configuration comprenant un paramètre de périodicité de fenêtre, un paramètre de décalage de fenêtre et un paramètre de durée de fenêtre, pour les mesures de resélection de cellules sur la base de blocs de ss pour des états rrc_idle et rrc_inactive.