baber/WOPTO huggingface dataset:
Patent WO-2019140081-A1 (WO)
Title: Self-drilling anchor assembly
Inventor: DILL MICHAEL
IPC: F16B13/06
Filed: 2019-01-10
Abstract: A self-drilling anchor assembly including a drill bit and an anchor positioned over and attached to the drill bit. In various embodiments, the drill bit includes a shank, a drill head integrally connected to one end of the shank, and a threaded tail integrally connected to an opposite end of the shank. The tail includes a mechanical engaging structure that is engageable by a tool to rotate the drill bit, and a helical thread formation to facilitate attachment of a securing device such as nut and washer to the tail of the drill bit. The anchor includes an elongated generally tubular body including an inner surface defining a longitudinally extending inner channel, and a head integrally connected to and extending from a first end of the body. The drill bit is configured to remain in the anchor and in the substrate after installation of the anchor assembly in the substrate.
Patent WO-2019161105-A1 (WO)
Inventor: SCHMITGES FRANK
IPC: C12N15/12
Filed: 2019-02-14
Abstract: La présente invention concerne des oligonucléotides antisens, des compositions et des procédés ciblant l'exon 6 de l'ATP7B ou un intron flanquant, ce qui permet de moduler l'épissage de pré-ARNm de l'ATP7B pour augmenter le niveau de molécules d'ARNm ATP7B comportant l'exon 6, par exemple, pour fournir une thérapie pour la maladie de Wilson. La présente invention concerne un oligonucléotide antisens comprenant une séquence de nucléobase complémentaire à au moins 70 % d'une séquence cible ATP7B dans l'exon 6, un intron flanquant 5', un intron flanquant 3', ou une combinaison de l'exon 6 et de l'intron flanquant 5'ou 3'.
Patent WO-2019173841-A1 (WO)
Title: Integrated well construction system operations
Inventor: BOTNAN ESPEN
IPC: E21B44/00
Filed: 2019-03-11
Abstract: An integrated well construction system (IWCS, 100) operable for constructing a well via integrated control of integrated control devices that collectively control integrated subsystems of the IWCS. The IWCS includes an IWCS communication network, the integrated control devices (each directly connected with the IWCS communication network), the integrated subsystems, and a control workstation directly connected with the IWCS communication network and operable to control each of the integrated control devices to thereby control the integrated subsystems. During operation of the IWCS, data associated with the well construction operation is automatically collected and analyzed in real-time to determine parameters based on the data, and at least some of the determined parameters are used for controlling the well construction operation.
Patent WO-2019178022-A1 (WO)
Title: Apparatus and methods with surgical guides having routed liquid coolant irrigation
Inventor: RENNE WALTER
IPC: A61B17/88
Filed: 2019-03-12
Abstract: Provided herein are surgical guides with internal channels for irrigation cooling. In one embodiment, an apparatus for guiding a surgical instrument includes a proximal side and a distal side. A first channel is configured to guide a material removal device, where the first channel extends from the proximal side of the apparatus to the distal side of the apparatus. A second channel configured to direct irrigation fluid, where the second channel extends from the proximal side of the apparatus to the distal side of the apparatus. The first channel is separate from the second channel. A method of performing a surgical procedure and a method of manufacturing a surgical guide are also disclosed. In certain embodiments, the surgical guides may be manufactured via additive manufacturing processes, including for example, three-dimensional printing processes.
Patent WO-2019217508-A1 (WO)
Inventor: CHU MICHAEL
IPC: A61B1/00
Filed: 2019-05-08
Abstract: Un système médical (10) comprend un tube (24) et une pluralité de clips (26) qui fixent le tube dans une configuration partiellement en spirale. Le système médical comprend également une plateforme (16) couplée à une partie extérieure radiale du tube. La plateforme comprend au moins un trou (28) et une pluralité d'éléments de retenue (30).
Patent WO-2019217708-A1 (WO)
Title: Compounds and methods for reducing atxn3 expression
Inventor: FREIER SUSAN
IPC: C12N15/113
Filed: 2019-05-09
Abstract: Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of ATXN3 RNA in a cell or animal, and in certain embodiments reducing the amount of ATXN3 protein in a cell or animal. Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least one symptom or hallmark of a neurodegenerative disease. Such symptoms and hallmarks include motor dysfunction, aggregation formation, and neuron death. Such neurodegenerative diseases include spinocerebellar ataxia type 3(SCA3).
Patent WO-2019231876-A1 (WO)
Title: Systems and methods for combination high temperature and low temperature device formation
Inventor: CHANG YA-HUEI
IPC: H01L23/34
Filed: 2019-05-28
Abstract: Embodiments are related to systems and methods for forming devices that include both high temperature components and low temperature components. A method for making a system including a plurality of high temperature electronic devices and at least one low temperature electronic device comprises the steps of: providing a substrate; locating each high temperature electronic devices at respective locations on the substrate; and subsequent to locating the plurality of high temperature electronic devices on the substrate, locating the at least one low temperature electronic device over the substrate.
Patent WO-2020146003-A1 (WO)
Title: Système d'amélioration visuelle intégré à un dispositif mobile
Inventor: ZHANG FUYAO
IPC: G09G5/02
Filed: 2019-05-28
Abstract: La présente invention concerne des aspects d'un système d'amélioration visuelle intégré à un dispositif mobile. Les aspects peuvent comprendre un casque d'affichage pouvant être porté qui comprend un ou plusieurs modules d'affichage et un dispositif mobile connecté en communication avec le casque d'affichage pouvant être porté. Le dispositif mobile peut comprendre un premier écran, un module de détection d'affichage conçu pour détecter le ou les modules d'affichage et pour recevoir des paramètres d'affichage du casque d'affichage pouvant être porté, et un module de distribution de contenu conçu pour délivrer un contenu visuel sur le ou les modules d'affichage détectés conformément aux paramètres d'affichage.
Patent WO-2019232341-A1 (WO)
Title: Method of fracturing with natural gas
Inventor: GUPTA D V SATYANARAYANA
IPC: C09K8/70
Filed: 2019-05-31
Abstract: A fracturing method wherein a foamed or energized fluid comprising natural gas is introduced into a subterranean formation to enhance or create fractures and to enhance production of hydrocarbons from a reservoir penetrated by a wellbore.
Patent WO-2019236682-A1 (WO)
Title: Devices, cartridge, and sensors for controlling liquid movement and analyzing biological samples
Inventor: JAGTIANI ASHISH
IPC: B01L3/00
Filed: 2019-06-05
Abstract: Described herein are cartridges and devices for operating said cartridges for analyzing a biological sample, such as a blood or saliva sample. Also described herein is an impedance sensor for analyzing a biological sample. Further described herein are methods of determining a cell count or detecting an analyte in a biological sample, which can include transporting the biological sample through a sensor comprising a channel or pore; applying an electrical current or voltage to the channel or pore; detecting an impedance within the channel or pore; and determining a cell count or detecting the analyte based on the detected impedance. Also described herein is an electrowetting electrode array that is configured to transport aqueous solutions using low voltage, such as about 50 volts or less. Further described herein are methods of transporting an aqueous liquid using electrowetting electrodes.
Patent WO-2020006012-A1 (WO)
Title: Microphone array with automated adaptive beam tracking
Inventor: MCCOWAN IAIN ALEXANDER
IPC: G10L21/0216
Filed: 2019-06-25
Abstract: An example method of operation may include initializing a microphone array in a defined space to receive one or more sound instances based on a preliminary beamform tracking configuration, detecting the one or more sound instances within the defined space via the microphone array, modifying the preliminary beamform tracking configuration, based on a location of the one or more sound instances, to create a modified beamform tracking configuration, and saving the modified beamform tracking configuration in a memory of a microphone array controller.
Patent WO-2020014036-A1 (WO)
Title: Methods for multicolor multiplex imaging
Inventor: WOOD DOUGLAS
IPC: G01N33/58
Filed: 2019-07-02
Abstract: Methods for multicolor multiplex imaging are provided herein in order to increase the number of targets that may be imaged given the number of fluorophores available or desired for use.
Patent WO-2020014275-A1 (WO)
Title: Electronic devices with display operation based on eye activity
Inventor: AGAOGLU MEHMET
IPC: A61B3/113
Filed: 2019-07-09
Abstract: An electronic device may have a display for displaying image content. Head- mounted support structures in the device may be used to support the display. The electronic device may have an eye monitoring system that detects eye saccades and eye blinks. Control circuitry in the electronic device may coordinate operation of the display with periods of suppressed visual sensitivity that are associated with the saccades and blinks. By making adjustments to display circuitry and image content during periods of suppressed visual sensitivity, potentially visually obtrusive changes to displayed images can be hidden from a user of the electronic device. Adjustments to display operation may help reduce bum-in effects, may help reduce power consumption, and may otherwise improve device performance.
Patent WO-2020023521-A1 (WO)
Inventor: GAUL JOSEPHINE
IPC: A23L1/29
Filed: 2019-07-23
Abstract: La présente invention concerne des compositions et des procédés contenant une lipase linguale ou une autre estérase prégastrique en tant que composition nutritionnelle destinée à être utilisée chez des mammifères néonataux ou des mammifères atteints de maldigestion de matière grasse. Les compositions peuvent être utilisées en tant qu'aliment autonome, ou en tant qu'additif pour le lait, lait ou succédanés. La composition peut également comprendre des micronutriments, des macronutriments et des composants alimentaires bioactifs pour des mammifères néonataux ou des mammifères d'âge quelconque atteins de maldigestion de matière grasse. Les mammifères comprennent des ruminants, des porcins, des chevaux, des camélidés, des chiens, des chats ou des êtres humains. La lipase linguale ou l'estérase prégastrique en tant que supplément nutritionnel peut sensiblement améliorer la digestion de matières grasses chez les mammifères ne pouvant pas digérer efficacement les matières grasses. La lipase ou estérase linguale provient de préférence d'une source animale. La composition peut contenir de la matière grasse de beurre, de la caséine micellaire, du lactosérum, des protéines non dénaturées et une source de lactose. L'invention concerne également des procédés de traitement de maldigestion de matière grasse avec les compositions.
Patent WO-2020028593-A1 (WO)
Title: A method of treating er mutant expressing breast cancers with selective androgen receptor modulators (sarms)
Inventor: NARAYANAN RAMESH
IPC: A61K31/277
Filed: 2019-07-31
Abstract: This invention relates to the treatment of breast cancer in a subject, for example a female subject. Including methods of: treating metastatic breast cancer; refractory breast cancer; AR-positive breast cancer; AR-positive refractory breast cancer; AR-positive metastatic breast cancer; AR-positive and ER-positive breast cancer; triple negative breast cancer; advanced breast cancer; breast cancer that has failed selective estrogen receptor modulator (SERM) (tamoxifen, toremifene, raloxifene), gonadotropin-releasing hormone (GnRH) agonist (goserelin), aromatase inhibitor (AI) (letrozole, anastrozole, exemestane), cyclin-dependent kinase 4/6 (CDK 4/6) inhibitor (palbociclib (Ibrance), ribociclib (Kisqali), abemaciclib (Vorzenio)), mTOR inhibitor (everolimus), trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, neratinib (Nerlynx), olaparib (Lynparza) (an inhibitor of the enzyme poly ADP ribose polymerase (PARP)), bevacizumab (Avastin), and/or fulvestrant treatments; metastasis in a subject suffering from breast cancer; HER2-positive; and/or treating a subject suffering from ER mutant expressing breast cancer, comprising administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound.
Patent WO-2020036941-A1 (WO)
Title: Bearing protector
Inventor: VADDER DAVEY JOE
IPC: F16J9/14
Filed: 2019-08-13
Abstract: A split bearing protector with a flexible design that adds improved moisture protection to a bearing and can be installed without removing the bearing from the machine in which it is installed.
Patent WO-2020037205-A1 (WO)
Title: Methods for de novo protein sequencing
Inventor: MAO YUAN
IPC: G01N33/68
Filed: 2019-08-16
Abstract: A method for determining an amino acid sequence of a polypeptide, including: contacting first and second samples containing the polypeptide with a first protease ( e.g. , Trypsin) and a second protease ( e.g. , Tryp-N), respectively, to produce first and second sets of digested peptide fragments; fragmenting the sets of digested peptide fragments to produce sets of fragmented peptide ions; selecting pairs of peptide ions from the sets of peptide ions that differ in mass by a mass of an arginine or lysine amino acid residue; assigning an ion type (N-terminal or C-terminal peptide ion) to the selected pairs of peptide ions from the two sets; selecting a mass ladder of the same-type peptide ions in either set of peptide ions with incremental mass by the mass of amino acid residue(s), and assembling the identified amino acid residues from the mass ladder to determine the amino acid sequence of the polypeptide of interest.
Patent WO-2021045784-A1 (WO)
Title: System and method for determining an appropriate dose of a product
Inventor: KEENAN JOSEPH FRANCIS
IPC: G16H20/10
Filed: 2019-09-06
Abstract: Provided is a system and method for determining an appropriate dosage of a product. The method includes, receiving from a User a User Request for a Dosage, the User Request including at least a User Reason and a User Location; accessing a Database of Products, each Product having at least one Constituent, at least one Established Reason, a Dosage for each Established Reason, and Provider Location; querying the Database of Products with the User Request to determine at least a first subset of Products having the at least one Established Reason correlating to the User Reason; and providing the User with the first subset of Products arranged by proximity of the Provider Location to the User Location, the first subset of Products further including the Dosage for each Product in the first subset of Products. An associated system is also provided.
Patent WO-2020061548-A1 (WO)
Inventor: MENENDEZ CARLOS
IPC: E21B37/06
Filed: 2019-09-21
Abstract: An organic blend chemical additive comprising more than 50 wt.% organic solvent (e.g. methanol and/or ethylene glycol), less than 10 wt.% water, a nitrate salt, a maleic acid copolymer, and optionally an imidazoline may be delivered to a production well through a conduit having a stainless steel and corrosion resistant metal alloy surface, such as a capillary string or an umbilical tubing, the organic blend chemical additive being shown to be useful in inhibiting localized corrosion of and improving the repassivation of the equipment or conduit.
Patent WO-2020068897-A1 (WO)
Title: Engineered dcas9 with reduced toxicity and its use in genetic circuits
Inventor: VOIGT CHRISTOPHER
IPC: C12N15/63
Filed: 2019-09-25
Abstract: Disclosed herein are novel CRISPR/dCas9-based fusion proteins that facilitate the scaling up of genetic circuits, including those with non-linear response curves. The dCas9- based fusion proteins produce significantly less toxicity in comparison to previously described CRISPR/Cas9-based proteins used with logic gates. These improvements enable the generation of complex genetic circuits when both digital response curves and large amounts of dCas9 protein are needed. Also disclosed herein are methods of regulating expression of an output sequence through the introduction of novel CRISPR/dCas-9-based fusion proteins and genetic circuits into a cell.
Patent WO-2021061129-A1 (WO)
Title: Anti-biofouling of submerged lighting fixtures
Inventor: USHER SCOTT
IPC: B08B17/02
Filed: 2019-09-26
Abstract: A lighting fixture and method resist bio-fouling of a window of the lighting fixture when submerged and exposed to biological organisms within a surrounding environment. Ultraviolet radiation is directed to the window from a source within the fixture, enabling transmission of the ultraviolet radiation through the window to an outer surface of the window to combat adherence of biological organisms to which the outer surface of the window is exposed when submerged, and allowing visible light from a source behind the window to be projected effectively through the window and into the surrounding environment.
Patent WO-2020072649-A1 (WO)
Title: Apparatus for an inert anode plating cell
Inventor: KEARNS GREGORY
IPC: H01L21/288
Filed: 2019-10-02
Abstract: In one example, an electroplating apparatus is provided for electroplating a wafer. The electroplating apparatus comprises a wafer holder for holding a wafer during an electroplating operation and a plating cell configured to contain an electrolyte during the electroplating operation. An anode chamber is disposed within the plating cell, and a charge plate is disposed within the anode chamber. An anode is positioned above the charge plate within the anode chamber. In some examples, the anode chamber is a membrane-less anode chamber.
Patent WO-2020086266-A1 (WO)
Title: Translating combinations of user gaze direction and predetermined facial gestures into user input instructions for near-eye-display (ned) devices
Inventor: PACE MARIA ESTHER
IPC: G02B27/01
Filed: 2019-10-09
Abstract: A Near-Eye-Display (NED) devices that translates combinations of user gaze direction and predetermined facial gestures into user input instructions. The NED device includes an eye tracking system and a display that renders computer-generated images within a user's field-of-view. The eye tracking system may continually track the user's eye movements with a high degree of accuracy to identify specific computer-generated images that a user is focused on. The eye tracking system may also identify various facial gestures such as, for example, left-eye blinks and/or right-eye blinks that are performed while the specific computer-generated images are being focused on. In this way, NED devices are enabled to identify combinations of user gaze direction and predetermined facial gestures and to translate these identified combinations into user input instructions that correspond to specific computer-generated images.
Patent WO-2020092817-A1 (WO)
Title: Configuration of resource patterns for integrated access and backhaul
Inventor: ABEDINI NAVID
IPC: H04W28/02
Filed: 2019-10-31
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, an integrated access and backhaul (IAB) node may receive at least part of a resource pattern of a child IAB node associated with the IAB node. The resource pattern may indicate one or more configurations of one or more resources of the child IAB node. The IAB node may communicate with the child IAB node based on the at least part of the resource pattern. Numerous other aspects are provided.
Patent WO-2020092954-A1 (WO)
Inventor: PLISKA ADAM
IPC: G05B19/409
Filed: 2019-11-01
Abstract: Systems and methods to design part weld processes are disclosed. An example system to generate weld instructions for display to a weld operator during a welding sequence includes: a processor and machine readable instructions which cause the processor to: provide an interface to define a weld program including a sequence of weld instructions for display to a weld operator during a weld sequence, the weld program including a plurality of properties; determine, for each of the weld instructions, respective values for one or more properties that are defined via the interface; and generate the weld program including the sequence of weld instructions by, for each of the weld instructions in the sequence of weld instructions: determining default values for the properties that have not been defined for the weld instruction,; and generating a visual representation of the weld instruction using the defined values and using the determined default values.
Patent WO-2020102029-A1 (WO)
Title: Resonant transmission line to deliver precision rf voltage
Inventor: FLETCHER WILLIMA
IPC: H01J49/02
Filed: 2019-11-08
Abstract: A system for conveying a time-varying voltage signal from a first subsystem to a second subsystem, and for monitoring and controlling the time-varying voltage signal, comprises a transmission line having a first end and a second end, extending from the first end at the first subsystem to the second end at the second subsystem. The transmission line is configured to be un-terminated, and have an electrical length substantially equal to a multiple of one half wavelength of the time-varying voltage signal. The system may further comprise an adaptive control configured to couple the time-varying voltage signal to the first end, and adjust a generator of the time-varying voltage signal based on a sampling of the time-varying voltage signal at the first end, and at least one transformer at the second subsystem electrically coupled to the second end and configured to increase an amplitude of the time-varying voltage signal.
Patent WO-2020102199-A1 (WO)
Title: Harvester header having a segment control system
Inventor: HUNT CORY D
IPC: A01D41/14
Filed: 2019-11-12
Abstract: A header (112) of a harvester (100) includes a header segment (212), a center section (211), an actuator (510) coupling the header segment (212) to the center section (211), and a controller (708). The header segment (212) includes a cutter bar (208) configured to cut crops and the header segment (212) includes a first portion of a conveyor assembly (208). The center section (211) includes a second portion of the conveyor assembly (208), in which the center section (211) is configured to receive crops from the header segment (212) via the first portion of the conveyor assembly (208), and the second portion of the conveyor assembly (208) is configured to transport the received crops to a crop processing system (120) of the harvester (100). The controller (708) is configured to receive a signal indicative of a target position of the header segment (212) and the controller (708) is configured to control the actuator (510) to adjust the header segment (212) to the target position.
Patent WO-2020102739-A1 (WO)
Title: Agonistic tumor necrosis factor receptor superfamily polypeptides
Inventor: FAUSTMAN DENISE
IPC: C07K16/28
Filed: 2019-11-15
Abstract: Described are agonistic TNFR2 polypeptides, such as antibodies and antigen-binding fragments thereof, and the use of these polypeptides to stimulate the proliferation of regulatory T cells (Treg cells) and/or myeloid-derived suppressor cells (MDSCs), as well as to inhibit the function of, reduce the proliferation of, and/or directly kill, T effector cells, such as CD8+ T effector cells. The polypeptides, such as antibodies and antigen-binding fragments thereof, of the disclosure can be used, for example, to suppress autoimmunity and inflammation, as well as to promote the protection, healing, preservation, and/or regeneration of a wide variety of tissues and organs, such as tissues and organs containing TNFR2+ cells.