baber/WOPTO huggingface dataset:
Patent EP-1718624-B1 (EP)
Title: Derives de benzamide et leur utilisation en tant qu'activateurs de la glucokinase
Inventor: JOHNSTONE CRAIG
IPC: A61K31/427
Filed: 2005-02-15
Granted: 2009-03-25
Abstract: L'invention concerne les composés représentés par la formule (I): (I) dans laquelle R1 représente méthoxyméthyle; R2 est choisi parmi -C(O)NR4R5, -SO2NR4R5, -S(O)pR4 et HET-2; HET-1 représente un cycle hétéroaryle à 5 ou 6 éléments, à liaison C éventuellement substitué ; HET-2 représente un cycle hétérocyclyle à 4, 5 ou 6 éléments, éventuellement substitué, à liaison C ou N ; R3 est choisi parmi halo, fluorométhyle, difluorométhyle, trifluorométhyle, méthyle, méthoxy et cyano; R4 est choisi par exemple parmi hydrogène, alkyle (C1-4) éventuellement substitué et HET-2; R5 représente hydrogène ou alkyle (C1-4); ou R4 et R5 forment, conjointement avec l'atome d'azote auquel ils sont reliés, un système cyclique hétérocyclyle conforme à la définition de HET-3 ; HET-3 représente par exemple un cycle hétérocyclyle saturé ou partiellement insaturé à 4, 5 ou 6 éléments, éventuellement substitué; p représente (indépendamment dans chaque cas) 0, 1 ou 2; m représente 0 ou 1; n représente 0, 1 ou 2; à condition que lorsque m vaut 0, n vaut 1 ou 2; ou un sel, un promédicament ou un solvate de ces composés. L'invention porte également sur l'utilisation de ces composés en tant qu'activateurs de la GLK, des compositions pharmaceutiques contenant ces composés et des procédés de préparation de ces composés.
Patent EP-1704618-B1 (EP)
Inventor: HAUHE MARK S
IPC: H01Q1/00
Filed: 2005-01-13
Granted: 2010-08-25
Abstract: An antenna array is assembled by direct attaching a flip chip transmit/receive (T/R) module to an antenna circuit board. A fillet bond is applied to the circuit board and the flip chip T/R module around at least a portion of the periphery of the flip chip T/R module.
Patent EP-1730299-B1 (EP)
Inventor: VARADI KATALIN
IPC: C12Q1/56
Filed: 2005-03-30
Granted: 2011-06-01
Abstract: The invention provides a kit for measuring the thrombin generation in a sample of a patient's blood or plasma, or in a sample of clotting factors. The kit contains lyophilized tissue factor/phospholipid-complex and a lyophilized mixture containing a thrombin-substrate and CaCl2. The invention also provides processes for preparing the reagents for the kit. The kit can be used in a method for measuring the thrombin generation in a sample, wherein it is possible to detect changes in thrombin generation kinetics, for example after administration of inhibitor bypassing agents to a patient who has developed inhibitors to an exogenous clotting factor such as Factor VIII.
Patent EP-1735794-B1 (EP)
Inventor: IVANOV IVAN I
IPC: G11C7/22
Filed: 2005-03-31
Granted: 2011-04-27
Abstract: Improved integrated circuits, memory devices, circuitry, and data methods are described that facilitate the adjustment and reconstruction of signal timing of devices by providing for an interface having inputs and/or outputs that are adjustably delayed. This allows embodiments of the present invention to sense the signal delay and utilize adjustable input or output delays to correct the signal timing relationships such that correctly timed communication signals are received by the internal circuitry of the device. In one embodiment of the present invention, a register is utilized to adjust the timing delay of individual input and/or output signals for the device. This increases the robustness of the device and its resistance to communication or data corruption, allowing larger ranges of environmental conditions and input capacitances of systems or communication busses to be tolerated.
Patent EP-1879866-B1 (EP)
Inventor: VAN STRATEN NICOLE CORINE RENEE
IPC: A61P5/06
Filed: 2005-05-04
Granted: 2011-03-16
Abstract: The present invention relates to dihydropyridine derivatives having general formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, phenyl, (1-5C)heteroaryl R2, R3 are independently (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (1-4C)alkoxy, (24C)alkenyloxy, (2-4C)alkynyloxy, halogen X is SO2, CH2, C(O) or X is absent R4 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, (3-6C)cycloalkyl, (3-6C)cycloalkenyl, (3-6C)cycloalkyl(1-4C)alkyl, (2-6C)heterocycloalkyl, (2-6C)heterocycloalkyl(14C)alkyl, (6-1 OC)aryl, (6-10C)aryl(1-4C)alkyl, (1-9C)heteroaryl or (1-9C)heteroaryl(14C)alkyl. The compounds are useful for the treatment of fertility disorders.
Patent EP-1796860-B1 (EP)
Inventor: HOTZ WALTER
IPC: B21D37/20
Filed: 2005-09-08
Granted: 2008-08-06
Abstract: The invention relates to a forming tool (10), a method of modifying the surface of a workpiece wherein at least one surface of the workpiece comes into contact with the structured surface (14) of a forming tool (10) at least once and a method of structuring the outer surface of a forming tool (10). The invention is a forming tool (10) characterised in that it comprises a substrate (11) and a metallic glass layer (13) on at least the working face (12) of the forming tool (10) and the metallic glass layer (13) possesses a structured surface (14) for the purpose of reproducing the structured surface (14) of the metallic glass layer (13) in the surface of a workpiece. A tool (10) according to the invention may be used in the production of sheet and shaped parts for automotive use, the production of lithographic sheet, the production of coins and badges and the production of reflector sheet.
Patent EP-1814665-B1 (EP)
Inventor: EFFENHAUSER CARLO
IPC: B01L3/00
Filed: 2005-11-22
Granted: 2011-12-21
Abstract: A device for sampling, transporting and/or disposal of fluid media in the n1 and µl-range comprises a substrate with an open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open or closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.
Patent EP-1704653-B1 (EP)
Inventor: KODAMA NOBUTAKA
IPC: H04B3/54
Filed: 2005-12-28
Granted: 2010-07-21
Abstract: A communication system includes a synchronizing signal generator that generates a synchronizing signal based on a timing of an alternating waveform in a power line, a data communicating circuit that performs the data communication, and a communication controller that controls to acquire a transmitting right utilizing a timing of the synchronizing signal and to control the communication circuit in accordance with whether or not the communication apparatus acquires the transmitting right.
Patent EP-1836063-B1 (EP)
Inventor: HARTMAN HENK
IPC: B60D1/54
Filed: 2005-12-23
Granted: 2009-05-27
Abstract: Tow hitch assembly comprising a tow hitch member having a tow hitch rod and a tow hitch ball, and a holder device for the tow hitch member, wherein the holder device is provided with means for mounting the holder device to a vehicle, such as a passenger car, and an elongated holder member, wherein the tow hitch member is rotatable about an axis substantially parallel to the holder member, the tow hitch member being attached to the holder device so as to be movable in a direction substantially parallel to the holder member between a retracted and an extended position, and to be hingeable about a hinge axis substantially perpendicular to the holder member between a primary orientation in which the tow hitch ball has a low position and at least one secondary orientation in which the tow hitch ball has a higher position.
Patent EP-1833441-B1 (EP)
Inventor: PERKINS JAMES T
IPC: A61F9/007
Filed: 2005-12-19
Granted: 2010-08-04
Abstract: A length of tubing 20 includes an irrigation lumen 26 for carrying irrigation fluid from a source 12 to an ophthalmic surgical site at eye 18. An aspiration lumen 28 is also formed in tubing 20 for carrying aspirant from the surgical site at eye 18 to a collection reservoir. The irrigation lumen 26 and the aspiration lumen 28 include a compliant common wall 30. Wall 30 ensures that any surge occurring after an occlusion break during surgery is dampened because of the compliant common wall 30.
Patent EP-1691158-B1 (EP)
Inventor: REHBERG MICHAEL
IPC: F28F27/02
Filed: 2006-01-19
Granted: 2008-11-26
Abstract: The heat exchanger consists of a stack of plates (1) and close spacing (2, 2'). has one or both heat exchange media distributed between the plates by several identical distribution channels (3) at one end of the plates, and collected by a collection channels (4) at the other end. Guiding and diverting devices (5) ensure that the fluid always passes from the outermost plate edge into the space between the plates.
Patent EP-1772640-B1 (EP)
Inventor: HOFSCHULTE WOLFRAM
IPC: F16D7/00
Filed: 2006-05-03
Granted: 2009-02-18
Abstract: A plastic element (5), formed on the inner profile (4) of a hub (3) and/or the outer profile (2) of a shaft (1), is elastically deformed under the effect of a force exceeding a given threshold force to transmit force. The shaft is introduced into the inner profile of the hub in fitted manner to transmit torque. An independent claim is included for a hub.
Patent EP-1724285-B1 (EP)
Inventor: TAKEDA KAZUHIKO
IPC: C07K14/02
Filed: 2006-05-16
Granted: 2009-08-12
Abstract: An anti-HBs monoclonal antibody is described herein. This antibody can bind to the following: (i) a wild type HBsAg; (ii) at least one mutant HBsAg selected from the group consisting of a first mutant HBsAg and a second mutant HBsAg; and (iii) at least one mutant HBsAg selected from the group consisting of a third mutant HBsAg and a fourth mutant HBsAg. The first mutant HBsAg has a mutation at position 120. The second mutant HBsAg has a mutation at position 141. The third mutant HBsAg has a substitution to a lysine at position 118. The fourth mutant HBsAg has only one mutation at position 144 and an amino acid at the position 144 is substituted by a glutamic acid.
Patent EP-1719512-B1 (EP)
Inventor: XIA ZONGQIN
IPC: A61K31/58
Filed: 1999-03-26
Granted: 2011-05-04
Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
Patent EP-1726481-B1 (EP)
Inventor: WIDMANN GLENN R
IPC: B60Q1/52
Filed: 2006-05-08
Granted: 2010-02-17
Abstract: A lane change assist system (20) and method (80) are provided for assisting the driver of the vehicle in maneuvering a lane change. The system (20) includes a range sensor (24) mounted on a vehicle (10) for sensing range to an object (42) in a side detection zone (34) adjacent to one side of the vehicle (10). The system (20) also includes a controller (40) for determining when the side detection zone (34) is clear for the vehicle (10) to change lanes based on the sensed range signal. The controller (40) determines whether there is sufficient space to initial a lane change maneuver based on the sensed range signal and generates an output signal indicative thereof. An output is provided to warning lights (26, 28) indicative of the determined state for initiating the lane change maneuver.
Patent EP-1692942-B1 (EP)
Inventor: VAN DEN NIEUWELAAR ADRIANUS JODEPHUS
IPC: A22B3/08
Filed: 2000-01-14
Granted: 2010-04-07
Abstract: The invention relates to a conveyor device for conveying stunned or dead fowl between a stunning or killing installation and a carrier or processing device, which conveyor device imposes a distance between the stunned or dead fowl The conveyor device comprises a first belt conveyor for conveying the stunned or dead fowl from the stunning or killing installation in a random orientation and local density in a first direction; a second belt conveyor which leads from the first belt conveyor, for conveying the slaughter animals or the parts thereof in a second direction (166), which is essentially perpendicular to the first direction; and a third belt conveyor (154) for conveying the slaughter animals or the parts thereof in a direction (168), which is essentially similar to the first direction (168); wherein the first, second and third belt conveyors (150; 152;154) are mounted on respective rollers (156;158,160;162).
Patent EP-1705252-B1 (EP)
Inventor: TAKEKAWA YUKI
IPC: C12P13/04
Filed: 2006-03-20
Granted: 2008-07-16
Abstract: A method for producing (S)-N-protected-propargylglycine of the following formula (2), which comprises asymmetrically hydrolyzing an N-protected-propargylglycine of the following formula (1):      
wherein R 1  represents an alkyl group having 1 to 4 carbon atoms, R 2  and R 3  each independently represent a hydrogen atom or a protective group of an amino group, R 2  and R 3  being not simultaneously a hydrogen atom, and a carbon atom appended with a mark * represents an asymmetric carbon atom, 
using an asymmetric hydrolysis enzyme derived from a microorganism selected from Thermomyces genus, Aspergillus genus, Rhizopus genus, Penicillium genus, Pseudomonas genus, Humicola genus, Burkholderia genus, Candida genus and Streptomyces genus, or a cultured substance of a microorganism having an ability of producing this enzyme or a treated substance thereof, 
or using an asymmetric hydrolysis enzyme which is ±-amylase derived from a microorganism selected from Bacillus subtilis and Bacillus licheniformis.
Patent EP-1712858-B1 (EP)
Inventor: DUBETTIER-GRENIER RICHARD
IPC: F25J3/04
Filed: 2006-03-27
Granted: 2008-04-02
Abstract: The method involves cooling a water flow (23) in a cooling tower (25) that is supplied with carbon-di-oxide depleted gas (5) from its base and is supplied with water from its top. The gas (5) is provided from a vacuum pressure swing adsorption or vacuum swing adsorption or pressure swing adsorption type adsorption unit (3) which is supplied with a gas (1) to be treated and produces carbon-di-oxide enriched gas (7). Cooled water (27) is drawn from the tower at its base. An independent claim is also included for a water cooling apparatus.
Patent EP-1844517-B1 (EP)
Inventor: LARSEN PETER HALVOR
IPC: H01M4/88
Filed: 2006-02-02
Granted: 2010-04-21
Abstract: The present invention provides a method for producing a reversible solid oxide fuel cell, comprising the steps of: -providing a metallic support layer; -forming a cathode precursor layer on the metallic support layer; -forming an electrolyte layer on the cathode precursor layer; -sintering the obtained multilayer structure; -impregnating the cathode precursor layer so as to form a cathode layer; and-forming an anode layer on top of the electrolyte layer. Furthermore, a reversible SOFC is provided which is obtainable by said method. The method advantageously allows for a greater choice of anode materials, resulting in more freedom in cell design, depending on the desired application.
Patent EP-1976812-B1 (EP)
Inventor: GLOVER BRYAN K
IPC: C07C1/00
Filed: 2006-01-24
Granted: 2011-03-09
Abstract: La sélectivité moyenne du cycle du propylène d'un procédé de conversion d'un composé oxygéné en propylène (OTP) utilisant un catalyseur bifonctionnel de conversion d'un composé oxygéné est considérablement accrue par l'utilisation d'une combinaison : 1) d'une technologie de réacteur à lit mobile dans la partie de synthèse de l'hydrocarbure du schéma de procédé du procédé OTP au lieu de la technologie à lit fixe de l'art antérieur ; 2) d'un système catalyseur bifonctionnel et stabilisé de façon hydrothermale comprenant un tamis moléculaire ayant une capacité bifonctionnelle dispersé dans une matrice d'alumine modifiée par du phosphore contenant des anions labiles du phosphore et/ou de l'aluminium ; et 3) d'une durée de cycle continue du catalyseur inférieure ou égale à 400 heures. Ces conditions de procédé stabilisent le catalyseur vis-à-vis d'une désactivation hydrothermale et maintiennent l'accumulation de dépôts de coke sur le catalyseur à un niveau qui ne dégrade pratiquement pas l'activité du catalyseur bifonctionnel, le taux de conversion du composé oxygéné et la sélectivité vis-à-vis du propylène, ce qui permet de cette manière un rendement de production moyen du cycle du propylène proche des niveaux de début de cycle ou pratiquement au même niveau que ceux-ci.
Patent EP-1858520-B1 (EP)
Inventor: BARROW JAMES C
IPC: A61P25/18
Filed: 2006-03-08
Granted: 2011-10-05
Abstract: The present invention is directed to quinazolinone compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
Patent EP-1869780-B1 (EP)
Inventor: WANG MICHAEL MAO
IPC: H04W52/02
Filed: 2006-03-08
Granted: 2010-04-21
Abstract: Apparatus and methods for estimating the frequency of a sleep or slow clock by selectively utilizing an estimated sleep clock frequency and an estimated change in the sleep clock frequency. The disclosed apparatus includes a sleep clock frequency estimator to output a fast clock derived sleep clock frequency estimate and a sleep clock change frequency estimator to output an estimate of a change in frequency of the sleep clock. The apparatus further includes a combiner that weights at least one of the fast clock derived sleep clock frequency estimate to obtain a weighted sleep clock frequency estimate and the estimate of the change in frequency of the sleep clock to obtain a weighted estimate of the change in frequency of the sleep clock. The combiner also determines a new estimate of the sleep clock frequency using at least one of the weighted sleep clock frequency estimate and the weighted estimate of the change in frequency of the sleep clock. Complementary methods are also disclosed.
Patent EP-1910437-B1 (EP)
Inventor: DOERR SEBASTIAN
IPC: C08G18/08
Filed: 2006-06-20
Granted: 2010-04-21
Abstract: The present invention relates to a process for preparing self-crosslinking polyurethane dispersions by I) reacting a1) polyisocyanates with a2) at least one hydroxyl component having an average OH functionality of >=2 and a number average molecular weight of 62 to 2500 g/mol, wherein the hydroxyl component contains at least one acid-functional compound containing at least one isocyanate-reactive group, to form an NCO-functional and optionally OH-functional prepolymer, II) then reacting the NCO-functional and optionally OH-functional prepolymer with a3) a hydroxyl component having an average OH functionality of >1 and a4) optionally another polyisocyanate component, which may be the same as or different from a1), to form an OH-functional and NCO-free polyurethane, III) adding a blocked polyisocyanate either before, during or after the reaction of steps I) and II), or forming a blocked polyisocyanate in situ from a polyisocyanate and a blocking agent after the reaction of step II) has taken place, IV) neutralizing the acid groups of the resulting composition by adding a5) a neutralizing agent, and V) dispersing the resulting composition in water. The present invention also relates to the dispersions prepared by the present invention and to their use in coating, adhesive and sealant compositions.
Patent EP-1901617-B1 (EP)
Inventor: BANIEL AVRAHAM
IPC: A23L27/00
Filed: 2006-05-16
Granted: 2009-10-21
Abstract: The invention provides a sweetener composition comprising a core nano particle in association with a sweetener carbohydrate
Patent EP-1869865-B1 (EP)
Inventor: WEIS BRIAN E
IPC: H04L29/06
Filed: 2006-04-13
Granted: 2011-06-08
Abstract: A packet forwarding process, on a data communications device, forwards a packet to a plurality of destinations within a network from that data communications device using an “encrypt, then replicate” method. The packet forwarding process receives a packet that is to be transmitted to the plurality of destinations, and applies a security association to the packet using security information shared between the data communications device, and the plurality of destinations, to create a secured packet. The secured packet contains a header that has a source address and a destination address. The source address is inserted into the header, and then the packet forwarding process replicates the secured packet, once for each of the plurality of destinations. After replication, the destination address is inserted into the header, and the packet forwarding process transmits each replicated secured packet to each of the plurality of destinations authorized to maintain the security association.
Patent EP-1906931-B1 (EP)
Inventor: KARAVAS EVANGELOS
IPC: A61K9/20
Filed: 2006-06-29
Granted: 2008-12-03
Abstract: The present invention relates to the formulation of solid dosage forms for oral or sub-lingual administration comprising a therapeutically effective amount of an ACE inhibitor or a paharmaceutical acceptable salt thereof, and especially Fosinopril or Trandolapril or salts thereof, in combination with inorganic silica polymer such as Dimethicone, and a process for the preparation thereof by direct compression.
Patent EP-1931094-B1 (EP)
Inventor: DUAN XIAOQIN
IPC: H04L12/66
Filed: 2006-08-30
Granted: 2010-10-06
Abstract: A CS domain call terminating system, a method and a network device are disclosed. A routing-controlled determination module determines a call which has been subject to routing control in accordance with information carried in a received call initiation message and send routing-controlled information of the call to a subsequent call flow control module with; and the subsequent call flow control module determines and executes a subsequent call flow of the call in accordance with the received routing-controlled information. The network entity during CS domain call termination of the invention can obtain the routing-controlled information of the call, thereby avoiding repeated routing control and an indefinite subsequent call flow in the CS domain call terminating flow.
Patent EP-1933709-B1 (EP)
Inventor: BULBROOK GEORGE LEE
IPC: A61B6/12
Filed: 2006-10-09
Granted: 2011-09-21
Abstract: A prostate gland location and stabilization device comprising an elongate cylinder, sized to fit in the anal canal of a user, and having either a narrowing, or a bend (in the range from 20 to 60 degrees) located at or towards the axial mid-region of the cylinder. The cylinder has a heterogeneous internal structure arranged to define landmarks detectable by X-ray or magnetic resonance imaging. Additional features include an essentially flat handle, an internal gas channel and contrast markers. In some variants of the device, the heterogeneous structure comprises air-filled pockets. The invention also provides a method of locating the prostate gland of a patient using the device.
Patent EP-2087722-B1 (EP)
Inventor: NASKALI MATTI
IPC: H04N5/369
Filed: 2006-09-28
Granted: 2016-11-23
Abstract: The invention relates to an apparatus and method, for capturing an electronic image using a CMOS imager having an electronic shutter and a reduced dark current component in its image output signal. The dark current is reduced by reading out each line of the CMOS imager in normal and reversed order and subsequent processing.
Patent EP-1929452-B1 (EP)
Inventor: BALACHANDRAN GANESH K
IPC: H01L41/08
Filed: 2006-08-28
Granted: 2012-08-01
Abstract: A voltage regulation circuit (300) for an RFID circuit having a voltage limiter circuit (308) including a current sensing element for sensing current through the voltage limiter (308). the voltage limiter (308) generates a limited voltage. A voltage regulator (310) is coupled to the limited voltage for generating a regulated output voltage, the voltage regulator (310) has a dynamic biasing current responsive to an output of the sensing element for increasing bandwidth of the voltage regulator (310) when current in the voltage limiter circuit increases.