baber/WOPTO huggingface dataset:
Patent CA-3079767-A1 (CA)
Inventor: COLLIN-KROEPELIN MARIE-PIERRE
IPC: C07D401/14
Filed: 2018-10-17
Abstract: La présente invention concerne des promédicaments de 3-({3-(4-chlorophényl)-5-oxo-4-[(2S)-3,3,3-trifluoro- 2-hydroxypropyl] -4,5-dihydro- 1H-1,2,4-triazol-1-yl Jméthyl)-1- [3-(trifluorométhyl)-pyridin-2-yl] - 1H-1,2,4-triazole-5-carboxamide, 3-({3-(4-chlorophényl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2- hydroxypropyl] -4,5-dihydro- 1H-1,2,4-triazol-1-yl} méthyl)-1- [2-(trifluorométhyl)-phényl] -1H- 1,2,4-triazole-5-carboxamide et 3-({3-(4-chlorophényl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2- hydroxypropyl] -4,5-dihydro-1H-1,2,4-triazol-1-yl} méthyl)-1-(3-chloropyridin-2-yl)-1H-1,2,4- triazole-5-carboxamide, des procédés pour la préparation de tels composés, des compositions pharmaceutiques contenant de tels composés, et l'utilisation de tels composés ou compositions pour le traitement et/ou la prévention de maladies, en particulier pour le traitement et/ou la prévention de maladies rénales et cardiovasculaires.
Patent CA-3080143-A1 (CA)
Inventor: KLAERNER GERRIT
IPC: C08F8/02
Filed: 2018-11-03
Abstract: The present disclosure provides, inter alia, pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. In certain embodiments, the pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
Patent CA-3082286-A1 (CA)
Title: Topical emulsion composition containing nonsteroidal anti-inflammatory drug
Inventor: BAGCHI SAUMITRA
IPC: A61K9/00
Filed: 2018-11-28
Abstract: In one aspect, the present invention features an emulsion composition including (i) at least 3%, by weight, of a nonsteroidal anti-inflammatory drug; (ii) at least 15%, by weight, of isopropyl myristate; (iii) at least 25%, by weight, of water; and (iv) one or more emulsifiers; wherein the formulation is substantially free of C1-C4 alcohols.
Patent CA-3083452-A1 (CA)
Inventor: CROLL SUSAN D
IPC: C07K16/46
Filed: 2018-11-28
Abstract: Antibodies that bind specifically to TrkB and methods of using the same are disclosed. Agonist antibodies that are neuroprotective, as shown by their effect on enhancing the survival of retinal ganglion cells in vitro are disclosed, and these agonist antibodies may be used in treatments such as disorders of the eye, including glaucoma. In addition, other neuronal diseases or disorders benefit from treatment with these agonist antibodies, including those characterized in part by neuronal damage. In certain embodiments, the invention includes antibodies that bind TrkB and mediate cell signaling. The antibodies of the invention may be fully human, non-naturally occurring antibodies formulated with excipients for injection.
Patent CA-3085719-A1 (CA)
Title: Mais hybride x90n362
Inventor: ARBELBIDE MARTIN
IPC: A01H5/10
Filed: 2020-07-06
Abstract: Une nouvelle variété de maïs désignée X90N362, ainsi que sa semence, ses plants et ses parties de plant, est produite par croisement de variétés de maïs autogames. Des méthodes de production dun plant de maïs comportent le croisement de la variété de maïs X90N362 avec un autre plant de maïs. Des méthodes sont décrites pour produire un plant de maïs qui renferme dans son matériel génétique au moins un des traits introgressés dans la X90N362 par rétrocroisement ou transformation génétique, et les semences, plants et parties de plant du maïs produits de ce fait. La variété de maïs X90N362, les semences, les plants produits à partir des semences et les variantes, les mutations et les légères modifications de la variété de maïs X90N362 sont divulgués. Des procédés de production de variétés de maïs dérivées de la variété X90N362 et des méthodes dutilisation de la variété X90N362 sont aussi décrits.
Patent CA-3088000-A1 (CA)
Title: Saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof
Inventor: YOKOTA MASAHIRO
IPC: A61K31/53
Filed: 2019-02-27
Abstract: The present invention pertains to: a saturated ring-condensed dihydropyrimidinone or dihydrotriazinone compound having ROR? antagonist activity or a pharmaceutically acceptable salt thereof; a pharmaceutical composition containing same; and a pharmaceutical use thereof. Provided are: a compound of formula [I] or a pharmaceutically acceptable salt thereof; a pharmaceutical composition containing same; and a pharmaceutical use thereof. [In the formula, the respective substituent groups are as defined in the description of the present application.]
Patent CA-3089004-A1 (CA)
Title: Stowable hood for apparel
Inventor: O'CONNOR COLN CARROLL
IPC: A42B1/06
Filed: 2019-02-19
Abstract: A hood for a garment, including a covering for a torso portion of an intended user. The torso portion includes a back section that includes at least two panels defining an interstitial space for stowing a flattened hood. The hood assembled to the garment includes one or more panels of drapable sheet material. The hood has a body having one or more perimetrical edges defining a facial area. The hood has a top section, with downwardly extending back and side sections. The hood is flattenable so as to either not (1) reduce the length or width of the hood relative to a donned state or (2) substantially overlap materials in the flattened state. The panels include an opening for receiving the hood into the interstitial space, the interstitial space being configured to receive and stow the hood in the flattened state.
Patent CA-3090405-A1 (CA)
Title: Multi-dimensional hemostatic product and method for producing the same
Inventor: CENTIS VALERIE
IPC: A61L24/04
Filed: 2019-02-15
Abstract: The invention relates to a printed hemostatic product having at least three-dimensions and being made of a stack of layers deposited on one another from a first external layer up to a second external layer, wherein adjacent layers of the stack of layers are joined together, and wherein at least one layer of the stack of layers has at least one portion made from an hemostatic flowable with a composition comprising: - non-cross-linked collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen; and - at least one monosaccharide. The invention also relates to a method for forming such an hemostatic product with a three-dimensional additive printer, and the use of an hemostatic flowable as a printing ink in such a three-dimensional additive printer.
Patent CA-3092372-A1 (CA)
Title: Tolerogenic liposomes and methods of use thereof
Inventor: JHAVERI ADITI
IPC: A61K47/28
Filed: 2019-02-26
Abstract: The invention provides compositions (e.g., liposomes) for treating diseases and conditions associated with pathologic immune responses and methods for formulating and administering such compositions.
Patent CA-3096774-A1 (CA)
Inventor: BURCHER BENJAMIN
IPC: C01B3/06
Filed: 2019-04-30
Abstract: The present invention relates to a process for producing and for regenerating siloxane hydrogen carrier compounds.
Patent CA-3097077-A1 (CA)
Title: Compositions de cafeine et procedes d'utilisation
Inventor: CHIRILA TRAIAN VASILE
IPC: A61K31/522
Filed: 2019-04-15
Abstract: L'invention concerne une composition pharmaceutique formulée pour une administration intranasale comprenant un extrait de caféine naturelle, un excipient pharmaceutiquement acceptable, un support aqueux pharmaceutiquement acceptable; et, éventuellement, de la caféine supplémentaire, ou un sel, un solvate, un dérivé ou un métabolite pharmaceutiquement acceptable de celui-ci. L'invention concerne également des procédés de préparation et des procédés d'utilisation.
Patent CA-3097503-A1 (CA)
Title: Sustained release formulations of dysoxylum binectariferum
Inventor: BHARATE SONALI SANDIP
IPC: A61K9/16
Filed: 2019-04-18
Abstract: The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/ or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-rich Dysoxylum binectariferum with polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases.
Patent CA-3097866-A1 (CA)
Inventor: COMOR JOZEF
IPC: G21G1/12
Filed: 2020-11-03
Abstract: - 14 - Abrégé Méthode de production dAc-225 à partir de Ra-226 Il est décrit une méthode visant à produire de lAc-225 à partir de Ra-226, ledit Ra-226 étant présent en tant que solution liquide dans un récipient, ledit Ra-226 étant soumis à un procédé photonucléaire au cours duquel le Ra-226 (y,n) est irradié de façon à produire du Ra-225, qui se désintègre alors en Ac-225, lAc-225 ainsi formé étant recueilli par une précipitation électrochimique de celui-ci sur une cathode présente dans ledit récipient, ladite cathode étant retirée dudit récipient après ladite précipitation et placée dans un environnement de cellule de haute activité où ledit Ac-225 est extrait de ladite cathode. Fig. 2 Date Recue/Date Received 2020-11-03
Patent CA-3098545-A1 (CA)
Title: Cutting insert having land with spaced apart upwardly bulging land portions and non-rotary cutting tool provided therewith
Inventor: CHISTYAKOV SERGEY
IPC: B23B29/04
Filed: 2019-01-08
Abstract: A cutting insert (20) has a cutting portion (38) corner formed at the intersection of a rake surface (42), a forward cutting portion surface (40) and a relief surface (44). A cutting edge (52) is formed at an intersection of the rake surface (42) and the relief surface (44) with a land that (66) is located on the rake surface (42) and that extends along, and negatively away from, the cutting edge (52). A chip-control arrangement (72) is located at the rake surface (42) and includes an elongated projection (74) and plurality of spaced apart elongated protuberances (84) that extend from the projection (74) to the cutting edge (52), so that the land (66) has a plurality of spaced apart bulging land portions (86). A non-rotary cutting tool (96) has an insert holder (36) having an insert pocket (34) and the cutting insert (20) releasably retained therein.
Patent CA-3103659-A1 (CA)
Inventor: JALLOUL TONY MOUSSA
IPC: B65G43/00
Filed: 2019-06-10
Abstract: Provided are a method and apparatus for effectively facilitating, via a dynamic display system, a passenger's collection of checked-in bags from carousels of a baggage claim area. The dynamic display system may include: a memory storing instructions; one or more displays; and at least one processor configured to execute the instructions to: obtain the baggage information corresponding to baggage of a passenger, and control to display, in real time during travel of the corresponding baggage along a baggage carousel, the obtained bag information to move, on a screen of the one or more displays, in synchronization with the corresponding baggage along the baggage carousel.
Patent CA-3104283-A1 (CA)
Inventor: MILLER JAMES V
IPC: E05B65/00
Filed: 2019-06-20
Abstract: A base slat pry stopper, such as a base slat locking bracket, for locking a rolling shutter curtain covering an opening of a structure is disclosed. The base slat pry stopper may include a bracket base plate mounted to an opening bottom wall on an interior side of the shutter curtain, and a base slat engagement portion extending upward from the bracket base plate and above a top surface of the opening bottom wall. When the shutter curtain is unrolled to cover the opening, the base slat engagement portion engages the base slat to prevent the base slat from deflecting upward away from the opening bottom wall when a force applied from an exterior side of the shutter curtain causes the base slat to deflect toward the interior side of the structure and the shutter curtain. The base slat pry stopper may be permanently or removably installed.
Patent CA-3104715-A1 (CA)
Inventor: AHER ANKUR ANIL
IPC: G06F16/78
Filed: 2019-12-11
Abstract: Systems and methods for generating media program keywords based on a video- hosting website are disclosed herein. Control circuitry identifies, on the video-hosting website, video content items that include at least a portion of a media program. The media program has a media program identifier and the video content items have respective titles, each including one or more terms. The control circuitry identifies a term included in more than one of the titles and identifies a group of the video content items that have the term included in their title. Based on the video-hosting website, the control circuitry determines a cumulative number of rankings of the video content items within the group and generates a relevance score for the term based on the cumulative number of rankings. The control circuitry stores the term and the relevance score in a keyword database in association with the media program identifier.
Patent CA-3105409-A1 (CA)
Title: Fungicidally active combination of a clonostachys strain and an azole
Inventor: DAHMEN PETER
IPC: A01N43/653
Filed: 2019-06-27
Abstract: The present invention relates to a composition comprising a fungicidally active Clonostachys rosea strain and a fungicidally active azole and methods of using this composition for reducing the DON content in cereal grains infected with Fusarium head blight.
Patent CA-3108738-A1 (CA)
Inventor: RAN-RESSLER RINAT
IPC: A61P5/48
Filed: 2019-09-20
Abstract: A method of treating exocrine pancreatic insufficiency includes administering to an individual in need thereof (e.g., an individual with cystic fibrosis) an effective amount of an enteral composition having a total protein consisting essentially of hydrolyzed protein and a total fat containing monoacylglycerols (MAG) that are at least about 30 wt.% of the total fat, and the total fat optionally further contains medium chain triglycerides (MCT) and/or fatty acids. In one particular non- limiting embodiment, about 60 wt.% of the total fat is from MCT and about 40 wt.% of the total fat is from MAG; in another particular non- limiting embodiment, the total fat is MAG with free fatty acids (esterified and/or bound) without MCT; and in yet another particular non- limiting embodiment, the total fat is MAG alone without MCT.
Patent CA-3108955-A1 (CA)
Title: Hydraulic fracturing pump health monitor
Inventor: DONG ZHAOXU
IPC: E21B43/26
Filed: 2021-02-16
Abstract: A hydraulic fracturing machine includes a pump failure detection system. The hydraulic fracturing machine includes a hydraulic fracturing pump with a power end and a fluid end. The power end includes a plurality of roller bearings, and the fluid end includes a flow of fluid. A particle sensor coupled to the power end is configured to transmit particle information regarding a quantity of particles in the fluid. A temperature sensor, also coupled to the power end, is configured to transmit temperature information regarding a temperature of the fluid. A vibration sensor coupled to the power end is configured to transmit vibration information regarding a vibration of each of the plurality of roller bearings. An electronic control module analyzes the particle information, the temperature information and the vibration information, and calculates a failure warning level based on the analysis.
Patent CA-3109759-A1 (CA)
Inventor: JIANG WENHUI
IPC: E21B33/12
Filed: 2021-02-22
Abstract: A component of a downhole tool utilized in oil and natural gas exploration and production comprises inorganic hydrolysable compound-containing materials. The inorganic hydrolysable compounds grant the component the degradability/dissolution in aqueous environment. The inorganic hydrolysable compounds include, but not limited to, hydrolysable carbides, nitrides, and sulfides, such as aluminum carbide (A14C3), calcium carbide (CaC2), magnesium carbide (Mg2C3 or MgC2), manganese carbide (Mn3C), aluminum nitride (A1N), calcium nitride (Ca3N2), magnesium nitride (Mg3N2), aluminum sulfide (Al2S3), and aluminum magnesium carbide (Al2MgC2).
Patent CA-3110133-A1 (CA)
Inventor: LEWIS STEPHEN
IPC: B65D77/00
Filed: 2019-08-21
Abstract: Packaging for tobacco industry products is disclosed. The packaging comprises a pack (2) for holding tobacco industry products, and an outer wrapper (3) enveloping the pack. The outer wrapper comprises a removable portion (17) arranged to prevent opening of the pack until the removable portion has been removed. One of the pack and the removable portion comprises a tamper evident feature that remains attached to the other of the pack or the removable portion after the removable portion is removed from the pack. A method of packaging tobacco industry products is also disclosed.
Patent CA-3110318-A1 (CA)
Title: Utilisation d'agonistes des recepteurs adrenergiques alpha-2 pour ameliorer la vue
Inventor: DIBAS MOHAMMED
IPC: A61P27/10
Filed: 2019-08-20
Abstract: L'invention concerne des méthodes d'utilisation d'un agoniste de récepteurs adrénergiques alpha-2 de formule I : pour améliorer la vue, telles que dans le traitement d'affections oculaires telles que la presbytie, la mauvaise vision nocturne, l'éblouissement visuel, la vue de salves d'étoiles, de halos visuels, et certaines formes de myopie (par exemple la myopie nocturne).
Patent CA-3110634-A1 (CA)
Title: Wicking termination system
Inventor: CAMPBELL RICHARD V
IPC: B23P11/00
Filed: 2019-08-27
Abstract: A termination system which improves the consistency and repeatability of the wicking of the liquid potting compound in the transition area between the potted and the unpotted filaments. The termination system controllably compresses the filaments within the transition area to produce repeatable wicking. The potting compound selected and the degree of compression employed combine to produce a desired wicking effect.
Patent CA-3110652-A1 (CA)
Title: Procedes d'utilisation d'un compose phenoxypropylamine pour le traitement de la douleur
Inventor: LUTHRINGER REMY
IPC: A61P29/00
Filed: 2019-09-04
Abstract: La présente invention concerne des procédés de traitement de la douleur, de la fibromyalgie, de la neuropathie, de la douleur induite par une chimiothérapie, de promotion d'un effet antihyperalgésique, et de réduction de la sensibilité à la douleur, chez un sujet ayant besoin d'un tel traitement, comprenant l'administration d'une quantité thérapeutiquement efficace du composé I, ou d'un sel, solvate ou promédicament pharmaceutiquement acceptable de celui-ci.
Patent CA-3111132-A1 (CA)
Inventor: BRUENING JOERG
IPC: C07C237/06
Filed: 2011-09-23
Abstract: Une méthode de préparation dun composé de la formule 1 est décrite. La méthode en question utilise un groupe protecteur damine carbamate de benzyle et un intermédiaire de la formule 4.   Il est également décrit un composé phénylméthyle N-[2-oxo-2-[(2,2,2-trifluoroéthyle)amino]éthyle]carbamate (un composé de la Formule 4).
Patent CA-3112086-A1 (CA)
Title: Method for forming multilayer coating film
Inventor: GONTANI Haruyuki
IPC: B05D5/00
Filed: 2021-03-16
Abstract: This invention provides a method for forming a multilayer coating film that is capable of forming a multilayer coating film that has excellent blackness, high reflectance of an infrared laser, and excellent coating film performance. The method for forming a multilayer coating film includes forming a first colored coating film containing a titanium oxide pigment and in which the diffuse reflectance at a wavelength of 905 nm or diffuse reflectance at a wavelength of 1550 nm, or both, is 40% or more; forming a second colored coating film containing a carbon black pigment (A) and one or more pigments (B), which are a perylene black pigment (B1) or two or more pigments (B2) selected from the group consisting of blue pigments, red pigments, yellow pigments, and green pigments, or both (B1) and (B2); and forming a clear coating film; wherein the multilayer coating film has a lightness L*(450) of 4 or less and a chroma C*(450) of 2 or less, and wherein the diffuse reflectance at a wavelength of 905 nm or the diffuse reflectance at a wavelength of 1550 nm, or both, is 10% or more.
Patent CA-3114625-A1 (CA)
Title: Systeme de decoupe au laser destine a couper des articles et a former des tubes de filtration
Inventor: LI YONGWANG
IPC: B23K26/382
Filed: 2019-09-26
Abstract: L'invention concerne un système de découpe au laser destiné à couper des articles, tels que des tubes, et un procédé d'utilisation associé. Le système de découpe au laser peut découper des fentes, des trous et/ou des pores dans chaque article ou tube pour former des tubes de filtration, par exemple. Le système comprend un système d'émission destiné à émettre un faisceau laser à partir d'une source laser, au moins un miroir, une lentille d'objectif de focalisation, une source de gaz et une buse de distribution. Un premier étage maintient chaque article dans une direction longitudinale, et peut faire tourner l'article axialement pendant la distribution du gaz et l'émission du faisceau laser vers l'article et déplacer l'article longitudinalement par rapport à la buse de distribution. Un second étage présent dans le système est destiné à déplacer la buse de distribution par rapport à l'article qui est maintenu par le premier étage. Un dispositif de commande commande l'actionnement du faisceau laser et de la source de gaz, et le déplacement du premier étage et du second étage.
Patent CA-3118211-A1 (CA)
Inventor: BLANKENSTEIN THOMAS
IPC: C07K14/725
Filed: 2019-12-17
Abstract: The present invention is directed to the field of immunotherapy, in particular, adoptive T cell therapy or T cell receptor (TCR) gene therapy of cancer, in particular, of B cell lymphoma or B cell leukemia. The invention provides a nucleic acid encoding TCR alpha or beta chain constructs of TCR constructs capable of specifically binding to a peptide of SEQ ID NO: 1, derived from the lineage specific antigen CD22, in the context of HLA-A2 and to subsequently lyse CD22-positive cells. The invention further provides a corresponding protein and host cell, e.g., a CD8+ T cell, pharmaceutical compositions comprising the same, and therapeutic use for treatment of B cell lymphoma or B cell leukemia, such as diffuse large B-cell lymphoma (DLBCL).
Patent CA-3118348-A1 (CA)
Inventor: MAILLAUD LAURENT
IPC: C03C17/36
Filed: 2018-11-14
Abstract: The invention concerns a method for depositing a functional mineral layer or stack on a glass substrate, comprising the steps of depositing, on the substrate, a photosensitive laser-crosslinkable organic liquid resin composition, crosslinking the resin in a localised manner by means of a laser, eliminating the non-crosslinked liquid composition, depositing, on the coated substrate, a functional mineral layer or stack, then combusting the crosslinked solid resin by means of a heat treatment, completing its elimination and that of the mineral layer or stack by mechanical action, so as to obtain the mineral layer or stack in a pattern corresponding to the negative of that produced with the crosslinked solid resin; also disclosed is an intermediate product of this method and the application of the glazing obtained by this method to allow the passage of radiofrequencies.