baber/WOPTO huggingface dataset:
Patent CZ-186897-A3 (CZ)
Title: Use of molecules capable of binding mhc-ii or imitating mhc-ii for preparing a pharmaceutical preparation
Inventor: LAUENER ROGER PASCAL
IPC: C07K14/74
Filed: 1995-12-27
Abstract: The invention relates to MHC-II binding and/or MHC-II mimicking molecules for use in interfering in the interaction between an activation stimulus for MHC-II bearing cells, such as phagocytes and cell-bound MHC-II molecules, in the interaction between lipopolysaccharide (LPS) or LPS in a complex with other molecules, such as CD14 and LBP, and cell-bound MHC-II molecules, or in the interaction between products from Gram-positive bacteria or complexes of products from Gram-positive bacteria with molecules such as CD14, and cell-bound MHC-II molecules. The MHC-II binding molecule may be any anti-MHC-II antibody or fragment thereof, or any molecule derived from such an antibody such as humanized, bispecific or other engineered molecules and the like. The MHC-II binding molecule may be selected from the group consisting of CD14, fragments thereof, modified versions thereof, or peptides having MHC-II binding properties.
Patent CZ-223697-A3 (CZ)
Title: Substituted phenyl derivatives as endothelin antagonists
Inventor: PORTER BARRY
IPC: A61K31/425
Filed: 1996-01-22
Abstract: Compounds of formula (I) are described, wherein: R<1> is CN, CH2CN, CH=CHCN, CHO, or CH=CHCO2H; R<2> is aryl lower alkoxy, heteroaryl lower alkoxy, aryl lower alkylthio or heteroaryl lower alkylthio in which each of the aryl and heteroaryl moieties is optionally substituted; R<3> is halogen; R<4> is optionally substituted aryl or optionally substituted heteroaryl; R<5> is carboxy or an acid isostere; X is oxygen or sulphur; and n is zero or 1; and their N-oxides and prodrugs, and pharmaceutically acceptable salts thereof. The compounds have endothelin antagonist activity and are useful as pharmaceuticals.
Patent CZ-231896-A3 (CZ)
Title: Antiphlogistic cyclic heptapeptide
Inventor: FENICAL WILLIAM H
IPC: A61P31/04
Filed: 1995-02-16
Abstract: A cyclic heptapeptide anti-inflammatory agent named cyclomarin-A is disclosed. Cyclomarin-A is produced by a specific marine actinomycete. The cyclomarin-A producing bacterium is isolated from sediment located in marine estuaries in and around San Diego, Calif. Fermentation of the isolated bacterium in saltwater-based media produces cyclomarin-A as a secondary by-product. The cyclomarin-A is useful as an anti-inflammatory agent.
Patent CZ-245094-A3 (CZ)
Title: Hot-air drying apparatus
Inventor: DEMOORE HOWARD WARREN
IPC: F26B23/04
Filed: 1994-10-05
Abstract: A hot air dryer (10) utilizes high velocity air jets which scrub and break up the moist air layer which clings to the surface of a freshly printed sheet (S). High velocity air is heated to a high temperature as it flows along a resistance heating element (38) within an air delivery baffle tube (64). The heated, high velocity air pressurizes a plenum chamber (46) within an air distribution manifold (36W). High velocity jets of hot air are discharged through multiple airflow apertures (54) onto the wet ink side of a printed sheet as it moves through a dryer exposure zone (Z). An extractor (40) removes the moist air layer, high velocity hot air and volatiles from the printed sheet (S) and from the press (12). <IMAGE>
Patent CZ-264997-A3 (CZ)
Title: Process for preparing simvastatin from lovostatin or mevinolinic acid
Inventor: KUMAR YATENDRA
IPC: A61K31/351
Filed: 1997-08-20
Abstract: Preparation of simvastatin (6(R)-[2-[8(S)-(2,2-dimethylbutyryloxy)2-(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one) of formula (I) comprises: (a) treating a naphthyl ester with an alkyl amine of to give a naphthyl amide; (b) treating the amide with an alkali metal amide and then dried alkyl halide to give a methylated naphthyl amide; (c) hydrolysing the amide linkage and closing the open pyranone ring without protecting or deprotecting the two hydroxy groups of the ring, by treating with a strong base followed by treatment with ammonium hydroxide to give an ammonium salt; (d) relactonizing the salt by heating in a solvent to give (I). R2 = H, Na, K or NH4; R3 = 3-6C n-alkyl or cycloalkyl.
Patent CZ-283596-A3 (CZ)
Title: Process and apparatus for complex preparation of bioethanol from recoverable resources
Inventor: MACHEK FRANTISEK ING CSC
IPC: C12P7/06
Filed: 1996-09-26
Abstract: The method and equipment for complex production of bioethanol is based on the concurrent processing of lignocellulose and starch materials (renewable resources). The lignocellulose is hydrolysed in a thermal-pressure process and the non-hydrolysed remaining cellulose is processed by the enzyme cellulase. The starch is lysed using commercially produced amylase. The non-hydrolysed remaining starch is processed by the enzyme cellulase or hydrolysed in a thermal-pressure process. The heat from the hydrolysis solution is used to modify the starch. Enzymatic hydrolysis also takes place in the solution. After modification the glucose solution gained is fermented using replacement separated yeast in a fermenter. The fermented mash is preheated by the hydrolysis solution and distilled in a fermentation still. Un-thickened stillage is used to dilute the hydrolysis solution and exhaust water from rectification is used as diluting water for the thermal-pressure hydrolysis. The equipment used includes a disintegrator line with disintegrator (1), filling unit (28), hydrolysis set (2), connected to a high-pressure expander (3) and atmospheric expander (4) which separate the reaction mix into a liquid suspension and vapour phase. The liquid suspension is put into an apparatus (9) where it is separated into a glucose solution and a solid residue, which is variously processed in the thermal-pressure hydrolysis set (2) or enzymatic hydrolyser (11) using cellulase. The apparatus (9) is connected to the starch enzymatic hydrolyser (14), which is connected with the apparatus (15) for preparation of milled granules and the apparatus (16) for preparation of amylase. The starch enzymatic hydrolyser (14) is connected to a separator (17), from which the output of the solution is connected to an apparatus (18) for modification of the fermentation media and across a heat exchanger (19), then fermenter (20), which is connected through a yeast separator (21) to a distillation apparatus (22) and device (24) for rectification of evaporation residue (23).
Patent CZ-310398-A3 (CZ)
Title: Process for preparing peroxocarbonate, apparatus for making the same and sodium peroxocarbonate in the form of particles
Inventor: JAMES ALUN PRYCE
IPC: C11D3/39
Filed: 1997-03-27
Abstract: Sodium percarbonate exhibits a tendency to decompose in built compositions and particularly detergent compositions built with zeolites. The tendency can be ameliorated by selecting sodium percarbonate which intrinsically has a mean particle size of from 500 to 1000 microns and not more than 20% by weight of below 350 microns and has a moisture pick-up when measured in a test at 80% relative humidity and 32° C. after 24 hours of not greater than 30 g/1000 g sample. A suitable sodium percarbonate can be made most conveniently by crystallisation from a bulk saturated solution of sodium percarbonate in a crystalliser/classifier that does not employ a conventional chloride salting-out agent.
Patent CZ-9903164-A3 (CZ)
Title: Process and apparatus for feeding, clamping and working parts of vehicle bodies within a single working center, particularly by geometrical welding
Inventor: VOGT FRANZ-JOSEF
IPC: B62D65/00
Filed: 1998-02-19
Abstract: The invention concerns a method and a device for feeding, clamping, and processing, particularly for geometric welding of automobile body components in a work station. The inventive method consists of side-section clamping frames which, after receiving a body side section with the help of portal robots which travel along an elevated four-axle portal in the X-Y axis, are brought into the geometrical welding station, positioned at both sides of the body, and clamped with the parts to be welded and the welding robots are laterally swung and/or conveyed to the welding points next to the body conveyer system for geometrical welding. The device is characterized in that a four-axle portal (2) is arranged above the geometrical welding station and along which four-axle portal (2), on each side of the body conveyor system (1), at least one portal robot (3), from which side-section clamping frames (9) are hung, can travel in the X-Y axis between a position for receiving the body side sections (8) and a position for clamping and welding the body. The four-axle portal (2) consists of rails (5) which are stationary and parallel or at right angles to the body conveyor system (1), one or more cross members (4) which can travel along the rails (5), one or more portal robots (3) which can travel in the longitudinal direction of the cross members (4), and side-section clamping frames (9) which are vertically movable and/or rotatably attached about a vertical axis on the portal robot (3).
Patent CZ-344899-A3 (CZ)
Inventor: BENSON DOUGLAS HERRIN
IPC: B29C55/06
Filed: 1998-04-02
Abstract: Netkaná látka schopná zúžení se zavede do štěrbiny (14) mezi
dva válce (15,16). Zde se vystaví přírůstkovému roztahování
ve směru rovnoběžnéms prvnímsměrem. Dále se na netkanou
látku působí napínací silou ato mezi sestavou (26) a sestavou
mechanické stabilizace (38), která způsobíjejí zúžení. Zúžená
netkaná látka se mechanicky stabilizuje v sestavě mechanické
stabilizace (38), čímž vznikne stabilizovaná, roztažitelná,
zúžená netkaná látka. Tato látka se dá snadno roztá
Patent CZ-349195-A3 (CZ)
Title: Structure of directly heated cathode
Inventor: CHANG-SEOB KIM
IPC: H01J1/15
Filed: 1995-12-28
Abstract: A directly heated cathode structure includes a porous pellet (500) impregnated with electron radiating material, a cup-shaped container (510) for holding the porous pellet (500), a metal member (520) being welded at the base of the container (510), and a filament (600) arranged between the container (510) and the metal member (520), thereby restricting thermion emission through the base and sides of the pellet (500) and extending the life of the cathode structure. <IMAGE>
Patent ES-198345-A3 (ES)
Title: UN MEZCLADOR TERMOSTáTICO
Filed: 1951-06-14
Abstract: Un mezclador termostático perfeccionado de doble lámina que tiene las particularidades siguientes consideradas separadamente o en combinación: a) La lámina doble está conectada con su soporte por mediación de una laminilla flexible y una pieza particular solidaria de la lámina doble coopera con el dispositivo de regulación b) El regulador tiene una varilla que en un extremo ofrece una parte cónica y en el otro roscado cuyo paso corresponde a la ga a de las temperaturas en que el aparato debe utilizarse. c) El distribuidor de líquido frío y caliente es oscilante y es accionado por la lámina doble y unos alveolos practicados al desplazarse ante las llegadas del líquido regular éstas actuando como un relé. El distribuidor va montado dentro de otra pieza que toma la forma de un pequeño tambor sirviendo los bordes exteriores de esta pieza como topes para dicho distribuidor. d) Las membranas tienen piezas laterales de caucho o materia sintética y entre estas dos piezas laterales se comprende un disco rígido de diámetro conveniente. e) La pieza que forma soporte de membrana y ofrece un apoyo contra el cual se aplica esta membrana tiene una serie de orificios practicados en dicho hombro. f) Se disponen filtros antes de la llegada de líquido a la cámara de las membranas. g) Unas válvulas de retención van también dispuestas a las llegadas. h) Se ofrecen racores particulares para facilitar las visitas del mecanismo y unos dientes de orientación permiten volver a montar sin dificultad el dispositivo. i) Unas juntas de aplastamiento que actúan en los dos sentidos van dispuestas entre el citado racor y las piezas que sostienen las membranas. j) La lámina doble está recubierta por una capa que la protege contra la corrosión.
Patent SK-105599-A3 (SK)
Title: Process for the crystallization of a reverse transcriptase inhibitor and its form i, ii, and iii
Inventor: CLARKE WILLIAM
IPC: C07D265/18
Filed: 1998-02-02
Abstract: A method for crystallising (-)-6-chloro-4-cyclopropyl ethynyl 4-trifluoromethyl- 1,4-dihydro-2H- 3,1-benzoxazin-2-one of formula (I) comprises dissolving (I) in a solvent, then adding an antisolvent to initiate crystallisation. Also claimed are Forms I, II and III of (I).
Patent SK-132499-A3 (SK)
Inventor: CERNAK LADISLAV
IPC: E05C3/00
Filed: 1999-09-24
Abstract: Zamykací mechanizmus poklopu šachty pozostáva z uza- mykacieho kolíka (2) so závitom a vodiacej skrutky (1) s bezpečnostnou hlavou, pričom vodiaca skrutka je s pravotočivým alebo ľavotočivým závitom. Uzamykací kolík zapadá do otvoru v ráme šachty alebo pod prídavný rám na uzamykanie.
Patent SK-145394-A3 (SK)
Title: Inhalating apparatus
Inventor: HEROLD HEIKO
IPC: A61M15/00
Filed: 1994-11-29
Abstract: The inhalation device for inhaling a pulverulent, pharmacologically active medicament consists of a storage container (3) for the medicament (4), a manually activated dosing arrangement for preparing a separated quantity of inhalation substance which is taken up by the air current aspirated upon inhalation and is swirled, an air inlet channel (9), a swirl chamber (W), and a connection channel (8) between the swirl chamber (W) and the dosing arrangement, and with a mouthpiece channel leading out from the swirl chamber (W). The dosing arrangement in this case consists of a dosing drum (D) which has in its interior (5) a storage container (3) for the medicament. Furthermore, the air inlet channel (9) and the connection channel (8) are arranged in such a way that they run towards each other in a V shape. Thus, whenever a dosing procedure is carried out, a separated quantity of inhalation substance is made ready in a dome shape at the apex of the two air channels (8) and (9) running towards each other in a V shape. <IMAGE>
Patent SK-285692-A3 (SK)
Title: Mixture capsule for dental amalgam
Inventor: IHDE STEFAN
IPC: A61K6/847
Filed: 1992-09-17
Abstract: The invention describes a mixing capsule for dental amalgam made of glass, ceramics or glass ceramics which can be easily opened and decontaminated after the mixing process. It comprises two parts (20, 21) which are releasably connected to one another along their junction (22), especially with a releasable mechanical retaining means (40). <IMAGE>
Patent BE-1007019-A3 (BE)
Title: Chain sharpening machine for chain saw
IPC: B23D63/16
Filed: 1992-06-23
Granted: 1995-02-21
Abstract: The suspended grindstone (32) is held with its motor (10) by a casing (24)that swings (27), pivots (26) and rises (28) with all of its adjustment andlocking screws (33, 34, and 35) for choosing the sharpening angle and theheight of the depth limiting pin. The assembly is operated simultaneously byvirtue of a single lever (11). The advance of each tooth of the chain towardsthe grindstone is achieved by a lever (12) operating two parts: the first(15) equipped with an adjustable stop and a moveable latch (13) at the end ofthe course for blocking the chain against the chain guide of the saw. Thislever also has a retracting spring (29). Two lateral screws (5) pivot on anaxis (31) and are retractable when working with the machine, for adjustmentand adaptation to the wear on the grindstone (32) by raising it or removingit from the machine on the chain guide. Lastly, two blocking wing nuts (30)are used to fix the sharpener on the chain guide.
Patent BE-1007607-A3 (BE)
Title: Multilaagspiegel met verlopende brekingsindex.
Inventor: KEPPEL ANTON
IPC: G21K1/06
Filed: 1993-10-08
Granted: 1995-08-22
Abstract: Werkwijze voor het vervaardigen van multilaagspiegels voor toepassing met röntgenstraling. Gebruikelijke multilaagspiegels zijn opgebouwd uit discrete dunne lagen, in het algemeen bestaande uit afwisselend een absorptielaag en een spacerlaag. Om de oppervlakteruwheid van de dunne lagen tegen te gaan is het bekend om de lagen na opbrengen door ionen-etsen glad te maken. Een nadeel is dat het materiaal van één laag doordringt in de andere laag, waardoor de plaats van de grenslaag en de dikte van de lagen van de multilaagspiegel niet goed meer gedefinieerd is. Volgens de uitvinding wordt een multilaagspiegel vervaardigd door juist te bevorderen dat een der materialen in da laag met andere materiaal dringt, waarna de oorspronkelijke laagdikte van het eerste materiaal wordt weggeëtst. Door dit proces laag voor laag te herhalen ontstaat een multilaagspiegel die niet afwisselend uit homogene, discrete lagen van verschillend materiaal bestaat, maar uit zich telkens herhalende lagen van één der materialen waarin het andere materiaal is ingedrongen.
Patent BG-48924-A3 (BG)
Title: Method for preparing of biologically active means
Inventor: LAMBOV VESELIN N
IPC: A61K35/74
Filed: 1990-07-24
Abstract: The biologically active agents are applied in clinical and cosmic medical practice. The method has high capacity in terms of number and quantity of derived finished products, by meanwhile using a simple cultivation regime, while the derived products are chemically defined, have a wide-spectrum pharmacological activity and are virtually untoxic. The method in effect is the cultivation of a strain Khodotorula rubra RL, registered in NBIMCC under No. 1784, on a solid nutritional medium including glucose, peptone and AGAR in a proportion 2:1:2 for 70 to 120 hours at a mandatory access of light.
Patent BG-60083-A3 (BG)
Title: Pesticide and a method for plant protection control
Inventor: TIMMONS PHILIP R
IPC: A01N47/02
Filed: 1991-06-04
Abstract: Substituted 1-arylpyrrole compounds of formula (II) below, are useful as pesticides, in particular for the control of insects, arachnids, and nematodes. Processes to make the compounds and intermediates used for their preparation are described. Additionally, compositions containing the compounds and methods of use therefore are provided. The compounds are of a formula (II) <CHEM>  wherein typical substituents are: X is halogen or a group R<5>S(O)n, in which n is 0, 1 or 2 and R<5> is CF3, CCl3, CF2Cl, CFCl2, CF2Br, CHF2, CHCl2 or CHClF; R<1> is H, Br, SCH3, CH3 optionally substituted or alkoxyalkylideneimino;     R<2> is CN;     R<3> is H, Cl or CH3 optionally substituted;     Y is CF3 or Cl;     X<1> and X<4> are each Cl; and X<2> and X<3> are each H. e us
Patent WO-03062477-A3 (WO)
Title: Macroboulettes et un procede de production de ces macroboulettes
Inventor: VESCOVI DE ARAGAO RICARDO
IPC: C22B1/24
Filed: 2003-01-21
Abstract: L'invention concerne des boulettes et un procédé permettant de les produire. Ces boulettes, dont les dimensions se situent entre 14 et 25 mm, regroupent le charbon, la chaux et la bentonite comme additifs. Leur procédé de production consiste: a) à ajouter à un additif de concentré de minerai de fer broyé (88 %<325#): H2O, charbon, chaux et bentonite; b) à faire rouler ledit concentré sur un disque bouleteur afin d'agglomérer le matériau et former des boulettes vertes; c) à trier les boulettes par dimension en choisissant celles dont les dimensions se situent entre 14 et 25 mm; d) à renvoyer au disque bouleteur les boulettes dont les dimensions sont inférieures à 14 mm et supérieures à 25 mm; e) et à cuire les boulettes dans un four à grille droite aux fins du frittage des boulettes entre les oxydes.
Patent WO-0183518-A3 (WO)
Title: Molecules qui modulent la proteolyse dependant de l'ubiquitine et procedes d'identification de ces molecules
Inventor: NASH PIERS
IPC: C07K14/47
Filed: 2001-05-04
Abstract: Cette invention se rapporte à des procédés permettant d'identifier des composés qui modulent la protéolyse dépendant de l'ubiquitine, ainsi qu'à des composés identifiés à l'aide de ces procédés. Cette invention concerne également un nouveau motif peptidique appelé 'motif CPD', des molécules tirées de ce motif CPD, et des utilisations de ce motif CPD et de ces molécules.
Patent WO-0206361-A3 (WO)
Title: Nouveaux polymeres photochromes et procedes pour synthetiser ces derniers
Inventor: BRANDA NEIL R
IPC: C09K9/02
Filed: 2001-07-13
Abstract: Selon l'invention, la polymérisation par métathèse avec ouverture du cycle d'un monomère de 1,2-bis-(3-thiényl)-cyclopentène photochrome permet d'obtenir une série de nouveaux polymères qui présentent tous une interconversion photoactivée réversible entre leurs formes ouvertes incolores et leur formes fermées colorées.
Patent WO-03006913-A3 (WO)
Title: Paintball marker loader apparatus
Inventor: JONG PAUL GARFIELD
IPC: F41B11/02
Filed: 2002-07-10
Abstract: In one aspect, the invention is directed to a loader apparatus (10) for use with a paintball marker (14) including a base (18) attachable to the marker (14), a cartridge (16) removably attachable to the base (18) and a delivery conduit (20). The base (18) includes a motor (70), which drives a driven means (72) ending in a first gear (88). The cartridge (16) includes a paintball chamber (30) with an outlet (32), and a flow assistor (34) driven by a second gear (66) that meshes with the first gear (88) on the base (18). The chamber (30) includes a pressure plate (38) and spring assembly (40) which pushes the paintballs (12) in the chamber (30) towards the outlet (32). The flow assistor (34) includes a rotating generally funnel-shaped surface having bosses and dimples to enhance the agitation of paintballs (12) and to assist the flow of paintballs (12) from the chamber (30). The operation of the flow assistor (34) is controlled by a controller (74). The controller (74) receives input from an on/off switch (112) on the base (18), a second switch (126) which senses the presence of a cartridge (16) on the base (18), and a plurality of paintball sensors (92) located in the delivery conduit (20). Magnetic plates (116, 122) mounted in the cartridge (16) and in the base (18) mate to each other when the cartridge (16) is mounted to the base (18), helping to hold them together. Similarly, the base (18) includes an external battery pack (102) which is mounted to the base (18) by a magnetic plate arrangement. A tube (137) mounted in the base communicates with the paintball outlet (32) of the chamber (30), and with the paintball inlet (22) of the paintball marker (14).
Patent WO-2004029604-A3 (WO)
Title: Electronique de generateur de forme d'onde a base de circuits lc accordes
Inventor: POTVIN LUCIEN
IPC: H01J49/42
Filed: 2003-09-23
Abstract: L'invention concerne un appareil conçu pour produire un signal électrique à variation périodique en vue de créer un champ électrique à variation périodique entre les électrodes d'un spectromètre de mobilité ionique. L'appareil comporte un port de sortie. Un premier circuit accordé est conçu pour être électriquement couplé à une source d'alimentation externe et pour, en isolation, produire un signal électrique à variation périodique ayant une première fréquence. Le premier circuit accordé, couplé au port de sortie, produit un signal électrique de sortie ayant un composant au niveau de la première fréquence. Un second circuit accordé est conçu pour être électriquement couplé à une source d'alimentation externe et pour produire un second signal électrique à variation périodique ayant une seconde fréquence différente de la première. Le second circuit accordé est couplé au premier circuit accordé de façon que le signal électrique de sortie varie autour du premier signal électrique à variation périodique.
Patent CZ-2004146-A3 (CZ)
Inventor: VOJTASIK RADOVAN
IPC: E06B1/68
Filed: 2004-01-28
Abstract: Řešení se týká konstrukce okna a/nebo dveří ajejich umístění
ve stavební exteriérové konstrukci (1). Alespoňjedna strana
konstrukce okna je provedena tak, že pevnou součástí rámu
(3) okna nebo pevnou součástí stavební exteriérové konstrukce
(1)je zakončovací lišta (2), překrývající konstrukci rámu (8)
křídla a část výplně (9) křídla. Zakončovací lišta (2)je z její
vnější části překryta krycím profilem (4). Zakončovací lišta
(2) z vnitřní strany přiléhá přímo na výplň (9) křídla nebo na
čelní lištu (10), připevňující výplň (9) křídla.