baber/WOPTO huggingface dataset:
Patent CA-2277801-A1 (CA)
Title: Preparation of particles for inhalation
Inventor: WANG JUE
IPC: A61K47/48
Filed: 1997-11-17
Abstract: Particles incorporating a surfactant and/or a hydrophilic or hydrophobic complex of a positively or negatively charged therapeutic agent and a charged molecule of opposite charge for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the particles are made of a biodegradable material and have a tap density less than 0.4 g/cm3 and a mass mean diameter between 5 µm and 30 µm, which together yield an aerodynamic diameter of the particles of between approximately one and three microns. The particles may be formed of biodegradable materials such as biodegradable polymers. For example, the particles may be formed of poly(lactic acid) or poly(glycolic acid) or copolymers thereof. Alternatively, the particles may be formed solely of a therapeutic or diagnostic agent and a surfactant. Surfactants can be incorporated on the particule surface for example by coating the particle after particle formation, or by incorporating the surfactant in the material forming the particle prior to formation of the particle. Exemplary surfactants include phosphoglycerides such as dipalmitoyl phosphatidylcholine (DPPC). The particles can be effectively aerosolized for administration to the respiratory tract to permit systemic or local delivery of wide a variety of therapeutic agents. Formation of complexes of positively or negatively charged therapeutic agents with molecules of opposite charge can allow control of the release rate of the agents into the blood stream following administration.
Patent CA-2278829-A1 (CA)
Title: Process for the preparation of aromatic maleimides
Inventor: ULLRICH FRIEDRICH-WILHELM
IPC: C07D207/448
Filed: 1999-07-23
Abstract: Aromatic maleimides can be prepared by reacting corresponding aromatic amines with maleic anhydride in the presence of a solvent mixture of halogenated hydrocarbon and a dipolar aprotic solvent, with the addition of acid and a polymerization inhibitor.
Patent CA-2279000-A1 (CA)
Inventor: ROOVERS JACQUES
IPC: C08G77/50
Filed: 1999-07-28
Abstract: A silane or carbosilane dendrimer is modified with bridge moieties and polymer arms attached to the bridges to form hybrid dendrimer-star polymers. The bridge moieties are attached via Si-C bonds to the silane or dendrimer. The bridge has one or more reactive groups to which polymer arms are attached. Selected reactive groups on the bridge may serve as initiator sites for in situ polymerization of the arms. The polymer arms are of the polyether, polysulfide or polyester type. These arms may have functional groups which allow further modification and attachments. For this type of star polymer, the bridge has been found to increase resistance to hydrolysis at the silane- or dendrimer - arm junction. These star polymers are useful. e.g. as viscosity modifiers, component in molding resins, water solubilizer for hydrophobic molecules, surfactants and as carriers for drugs, prodrugs and other biological agents.
Patent CA-2281234-A1 (CA)
Title: High resolution pigment ink for impulse ink jet printing
Inventor: SARMA DEVERAKONDA
IPC: C09D11/10
Filed: 1999-08-31
Abstract: Impulse ink jet compositions are provided which are suitable for printing clear, well-defined alphanumeric text or low spread, narrow bar width bar codes on porous substrates such as Kraft paper or corrugated cardboard. In one embodiment, the ink compositions preferably comprise from about 20 to 50 percent by weight of a carbon black dispersion, from about 10 to 20 percent by weight of a dispersion medium, from about 40 to 60 percent by weight of a plasticizer and optionally an antioxidant additive. The antioxidant additive lowers the dissolved oxygen level in the ink, thereby enhancing the jetting performance of the printhead.
Patent CA-2282714-A1 (CA)
Inventor: ZUCKER ULRICH F
IPC: A63H33/08
Filed: 1999-02-12
Abstract: An interlocking toy block container comprises a plurality of adjoining panels (3, 5, 6, 7, 8) having an outer surface and defining an interior space. The panels include first and second panels, the first panel (3) being hinged to the second panel (8) and movable between an open position for providing access to the interior space and a closed position for containing an item in the interior space. Hinging means (19) are provided for rotatably connecting the first panel to the second panel, the hinging means lying at or below the plane of the outer surface of each of the first and second panels. Interlocking means (9) extend from one of said panels for interlocking with an adjoining block engaging means (13) on another of said panels for frictionally engaging the interlocking means of an adjoining block. Releasable locking means (31, 15a) are provided for selectively maintaining the first panel in a closed position.
Patent CA-2285664-A1 (CA)
Title: 4,1-benzoxazepines, their analogues, and their use as somatostatin agonists
Inventor: MIKI TAKASHI
IPC: C07D413/12
Filed: 1998-04-20
Abstract: The present invention provides a compound of formula (I), wherein ring A is an optionally substituted aromatic hydrocarbon ring or aromatic heterocyclic ring; ring B is an optionally substituted aromatic hydrocarbon ring or aromatic heterocyclic ring; Z is an optionally substituted cyclic group or linear hydrocarbon group; R1 is a hydrogen atom, an optionally substituted hydrocarbon group or heterocyclic ring; R2 is an optionally substituted amino group; D is a bond or an optionally substituted divalent hydrocarbon ring; E is a bond, -CON(R a)-, -N(R a)CO-, -N(R b)CON(R c)-, -N(R d)COO-, -N(R e)SO2-, -COO-, N(R f)-, -O-, -S-, -SO-, -SO2-, and formula (a) or (b) (in which R a, R b, R c, R d, R e and R f are respectively a hydrogen atom or an optionally substituted hydrocarbon group); G is a bond or an optionally divalent substituted hydrocarbon group; L is a divalent group; ring B may form an optionally substituted non-aromatic condensed nitrogen-containing heterocyclic ring by combining with R 2; X is two hydrogen atoms, an oxygen atom or a sulfur atom; ~ is a single bond or a double bond, and Y is a nitrogen atom when ~ is a double bond, or an oxygen atom, -N(R4)-, (in which R4 is a hydrogen atom, an optionally substituted hydrocarbon group or an acyl group) or S(O)n (in which n is 0, 1 or 2) when ~ is a single bond, or a salt thereof, which have somatostatin receptor agonistic action.
Patent CA-2287487-A1 (CA)
Title: Use of nk-1 receptor antagonists for treating eating disorders
Inventor: HEFTI FRANZ FRIDOLIN
IPC: A61K45/00
Filed: 1998-04-22
Abstract: The present invention provides the use of an NK-1 receptor antagonist, optionally with an anorectic agent, for the manufacture of a medicament for the treatment or prevention of eating disorders, methods of treatment using the NK-1 receptor antagonist and pharmaceutical compositions and products containing it.
Patent CA-2289080-A1 (CA)
Title: Contaminated soil remediation method
Inventor: DE ROUFFIGNAC ERIC
IPC: B09C1/00
Filed: 1998-06-03
Abstract: A method is provided to remove volatile liquid contaminates from a contaminated volume of earth, the contaminated volume lying above a non-contaminated layer of earth, the method including the step of heating the non-contaminated layer until the temperature of a substantial portion of the non-contaminated layer that is contiguous with the contaminated layer is at least the boiling point temperature of contaminated liquids so as to prevent vaporized contaminants to move downwards from the contaminated layer of earth.
Patent CA-2292415-A1 (CA)
Inventor: BUYSE MARIE-ANGE
IPC: C07K14/705
Filed: 1998-06-22
Abstract: The present invention relates to molecules, such as diabodies, tri- and tetravalent antibodies and small antigen binding peptides, which can cross-link or cross-react with the costimulatory molecules B7.1 and B7.2 expressed on professional antigen presenting cells (APCs) leading to the inhibition of antigen-specific T cell activation. The present invention also concerns methods to produce these molecules and use of these molecules to treat diseases, such as transplant rejection, graft versus host disease (GVHD), allergy and autoimmune diseases, where antigen-specific T cell activation is pathogenic.
Patent CA-2294233-A1 (CA)
Title: A computer graphics system
Inventor: HERKEN ROLF
IPC: G06T15/80
Filed: 1998-07-02
Abstract: A computer graphics system is described in which a new type of entity, referred to as a "phenomenon", can be created, instantiated and used in rendering an image of a scene. A phenomenon is an encapsulated shader DAG comprising one or more nodes, each comprising a shader, or an encapsulated set of such DAG's which are interconnected so as to cooperate, which are instantiated and attached to entities in the scene which are created during the scene definition process to define dirverse types of features of a scene. Phenomena selected for use by an operator in connection with a scene may be predefined, or they may constructed from base shader nodes by an operator using a phenomenon creator. The phenomenon editor allows the operator to view the effects produced by various settings for the parameter values which are selected.
Patent CA-2295994-A1 (CA)
Title: Peptides et composes se liant au recepteur de l'interleukine 5
Inventor: CHEN MIN-JIA
IPC: A61K38/00
Filed: 1997-06-16
Abstract: L'invention concerne des peptides et des mimétiques des peptides qui se lient au récepteur de l'interleukine 5. Ces peptides et ces mimétiques des peptides sont utiles pour traiter des troubles, tels que l'asthme, qui impliquent une mauvaise production de l'interleukine 5 ou une mauvaise réponse à l'interleukine 5 ainsi qu'une accumulation d'éosinophiles. Ces peptides et ces mimétiques présentent également une grande utilité dans des procédés de diagnostique utilisant des peptides marqués et des mimétiques de peptides.
Patent CA-2299042-A1 (CA)
Title: Motor vehicle ballast and method for increasing wheel traction
Inventor: SERAFIN WITOLD P
IPC: B60D1/52
Filed: 2000-02-21
Abstract: Apparatus and method are provided for temporarily enhancing traction of the rear wheels of a vehicle comprising removeably coupling ballast to a standard trailer hitch receiver. A transverse extending ballast member is secured to a short axial tongue which is coupled or de-coupled to the receiver. Preferably, the ballast is preferably a heavy transverse extending member, such as a piece of railroad rail or filled polygonal tubing. The axial tongue member may further extend rearwardly for affixing a hitch ball. The tongue is alternately restrained to the receiver using aligned ports in the receiver and the tongue for accepting a cross pin and cotter. In slippery conditions, the ballast is coupled to the receiver for increasing the normal force at the driving wheels. When conditions improve, the ballast is easily removed so as to reduce vehicle wear and lessen environmental impact. The ballast is preferably stored on a caster support for ensuring substantial alignment with the receiver for avoiding lifting and positioning difficulties.
Patent CA-2301001-A1 (CA)
Inventor: WILLEMSEN STEPHANUS
IPC: C03C25/28
Filed: 1998-08-05
Abstract: A process for the manufacture of a yarn provided with a superabsorbent material having a swelling value of at least 60 and having hydrophilic properties which is capable of absorbing and retaining quantities of water, characterized in that an aqueous solution comprising a water-soluble pre-superabsorbent material is applied onto the yarn, after which the yarn is dried and heated in order to cross-link or to polymerize the water-soluble pre-superabsorbent material to the superabsorbent material. The superabsorbent provides water blocking capabiltiy to the yarn, so that it is suitable for use as a strength member in water tight optical communication cables.
Patent CA-2301790-A1 (CA)
Inventor: COLEMAN CHARLES R
IPC: B24B13/005
Filed: 1999-06-18
Abstract: A two-piece lens block (10) allows for the rotation of an edged lens blank (5) in order to align the cylinder of the lens blank (5) correctly. The lens block (10) includes a substantially cylindrical base (12) having a first surface (13) facing the lens blank (5) and an opposed second surface (15) with a plurality of driving recesses (14) extending into the base (12) from the second surface (15). A rotatable ring member (22) surrounds the base (12) and includes a mounting surface (24) generally adjacent to the lens blank (5). An edged lens-shaped cavity (26) is provided in the ring member (22) and provides for nearly full surface contact of an attachment alloy (17) with a front surface of the lens blank (5) to alleviated distortion. The two-piece lens block (10) allows edged lens blanks (5) to be surfaced to finished lenses.
Patent CA-2302980-A1 (CA)
Inventor: ALAMGIR MOHAMED
IPC: H01M10/05
Filed: 2000-03-22
Abstract: The present invention provides a method of hermetically sealing an electrochemical cell. In the disclosed method, a coating of an adhesive composition is applied to an external metal tab that serves as a contact lead from the cell to a device within which the cell is employed. The adhesive coats and heremetically seals the tab surface thereby. The coating process can be executed by directly heat-sealing an adhesive film onto the tab surface. Alternatively, an aqueous suspension of the adhesive composition can be sprayed onto the tab surface, or the tab may be roll coated in the composition and thereafter subjected to heat treatment, causing the adhesive to melt and flow. The coated tab is thereafter welded to a corresponding current collector in the form of a metal foil. The complete cell assembly is heat-sealed in a final closure sealing member such that the sealed tabs extend therethrough.
Patent CA-2303079-A1 (CA)
Inventor: LYON GREGORY S
IPC: F16C32/06
Filed: 1999-07-09
Abstract: L'invention concerne un ensemble de support à mouvement linéaire qui comporte un chariot (12) muni d'une voie de support (14, 16), d'un orifice d'entrée de liquide et d'un passage d'alimentation en liquide reliant entre eux l'orifice d'entrée de liquide (40) et la voie de support (14, 16). Celle-ci comporte une partie de support de charge (22), une partie de retour (24) et deux parties de retournement (26) reliant entre elles la partie de support de charge (22) et la partie de retour (24). Le chariot (12) est destiné à permette un mouvement linéaire sur un rail (20). Une pluralité de d'éléments roulants (18) sont disposés sur la voie de support (14, 16) et une source de fluide hydrostatique pressurisé est reliée à l'orifice d'entrée de liquide (40) de façon à alimenter la voie de support (14, 16) en fluide hydrostatique pressurisé.
Patent CA-2303663-A1 (CA)
Inventor: LEWIS CLAIRE ELIZABETH
IPC: C07K14/155
Filed: 1998-09-23
Abstract: L'invention concerne un vecteur rétroviral. Le vecteur rétroviral comprend un site donneur d'épissure fonctionnelle et un site accepteur d'épissure fonctionnelle; le site donneur d'épissure fonctionnelle et le site accepteur d'épissure fonctionnelle flanquent une première séquence nucléotidique intéressante ("NOI"); le site donneur d'épissure fonctionnelle se trouve en amont du site accepteur d'épissure fonctionnelle et le vecteur rétroviral est dérivé d'un pro-vecteur rétroviral; le pro-vecteur rétroviral comprend une première séquence nucléotidique ("NS") capable de produire le site donneur d'épissure fonctionnelle et une deuxième NS capable de produire le site accepteur d'épissure fonctionnelle; et la première NS se trouve en aval de la deuxième NS; de sorte que le vecteur rétroviral est le résultat d'une transcription inverse du pro-vecteur rétroviral.
Patent CA-2305468-A1 (CA)
Inventor: GEORGE PASCAL
IPC: A61K31/36
Filed: 1998-10-07
Abstract: Compounds of general formula (I)   in which U represents a group of general formula (A) or (B)   in which formulae V represents a hydrogen or halogen atom, a(C1-C3) alkyl group or one or two (C1-C3) alkoxy groups, W and X each represent, respectively, either two oxygen atoms, or an oxygen atom and a CH2 group, or a CH2 group and an oxygen atom, or an oxygen atom and a CO group, n represents the number 0 or 1, R represents either a propyl group when U represents a group of general formula (A), or a hydrogen atom or a (C1-C3)alkyl group when U represents a group of general formula (B), Y represents one or more atoms or groups chosen from the following: hydrogen, halogen, (C1-C3) alkyl and (C1-C3) alkoxy, Z represents two hydrogen atoms or an oxygen atom.
Patent CA-2307203-A1 (CA)
Inventor: MOIIN HOSSEIN
IPC: G06F11/14
Filed: 1998-10-20
Abstract: L'intégrité et la disponibilité des données est assurée en empêchant un noeud d'un système de groupes réparti d'accéder à des données partagées en cas de défaillance de ce noeud ou des liens de communication avec ce noeud. Ce noeud ne peut pas accéder aux données partagées lors de ce type de détaillante. Le système assure que la défaillance est détectée en moins de temps qu'il n'en faudrait à un noeud secondaire pour permettre le commencement des activités d'E/S de l'utilisateur après la reconfiguration. La rapide détection de la défaillance est assurée en déterminant périodiquement à quelle configuration du groupe actuel chaque noeud pense appartenir. Chaque noeud maintient un numéro de séquence qui identifie la configuration actuelle du groupe. Périodiquement, chaque noeud échange son numéro de séquence avec tous les autres noeuds du groupe. Si un noeud particulier détecte qu'il pense appartenir à une configuration précédente par rapport à celle à laquelle appartient un autre noeud, ce noeud détermine que le groupe a été reconfiguré car ce noeud a effectué une reconfiguration en dernier. Par conséquent, ce noeud ne doit plus être membre du groupe. Le noeud ne peut alors pas accéder aux données partagées. En outre, si un noeud suspecte la défaillance d'un groupe, ce noeud va diffuser un message de reconfiguration à tous les autres noeuds du groupe par un réseau public. Etant donné que les messages sont envoyés par un réseau public, la défaillance des liaisons de communication privées entre les noeuds n'empêche pas la réception des messages de reconfiguration.
Patent CA-2307753-A1 (CA)
Inventor: RANCOURT YVON
IPC: F16D65/00
Filed: 2000-05-08
Abstract: A disc brake assembly for a vehicle wheel wherein the wheel includes a hub journaled to an axle on the vehicle and a housing mounted to the vehicle, an annular rotor disc within the housing and means mounting the rotor disc to the wheel which comprises an annular hub portion. The rotor disc includes an annular peripheral portion relative to an axial axis with an outer peripheral surface and at least a first radial planar friction surface on the annular peripheral portion. The rotor has a plurality of circumferentially spaced-apart slots extending axially through the peripheral portion and inwardly towards the axial axis from the outer peripheral surface thereof.
Patent CA-2308490-A1 (CA)
Title: Ergot de liaison pour stator
Inventor: CAREY TIMOTHY WILBUR
IPC: H02K1/00
Filed: 1999-09-09
Abstract: L'invention concerne un stator (126) comportant des parties saillantes (132) dépassant d'un bord extérieur (154) des tôles (148) du stator. Ces parties saillantes (132) forment une pointe (158). Lorsqu'on insère le stator dans un carter (102) de moteur, les parties saillantes frottent sur une surface intérieure du carter (102). Le contact entre les parties saillantes et le carter (102) permet la réalisation d'une liaison entre le stator (126) et le carter (102).
Patent CA-2310303-A1 (CA)
Title: Virtual accelerator for detecting an alarm condition within a pressurized gas sprinkler system and method thereof
Inventor: ASSELIN JEAN-PIERRE
IPC: A62C35/66
Filed: 2000-05-30
Abstract: The virtual accelerator is for detecting an alarm condition within a pressurized gas sprinkler system. It has a pressure monitor for monitoring pressure within the pressurized gas sprinkler system, and generating a pressure signal representative of the pressure thereof; a sampler for sampling the pressure signal at a given frequency during a predetermined period of time, and generating a series of pressure values; and a detector for detecting variations of the pressure values, and generating an alarm signal if the variations are within a predetermined range.  A method for detecting an alarm condition within a pressurized gas sprinkler system is also proposed.
Patent CA-2311906-A1 (CA)
Title: Base station system including parallel interference cancellation processor
Inventor: HAHM MARK DAVID
IPC: H04B1/10
Filed: 2000-06-16
Abstract: The base station system includes a cancellation processor connected to a plurality of conventional signal processors. Under the control of a controller, the signal processors acquire user signals in signals received by the base station antennas. The controller controls the cancellation processor to perform cancellation operations with respect to the acquired user signals. The cancellation processor includes first-nth filter stages. Each filter stage operates in the same manner. A filter stage obtains, in parallel, the acquired user signals from signals supplied thereto by estimating symbols in the acquired user signals under the control of the controller. The cancellation processor also includes a cancellation stage associated with each filter stage. Each cancellation stage cancels, in parallel, the obtained user signals output from the associated filter stage from the signals received by the base station antennas. The resulting residual signals output from a cancellation stage are supplied to the next filter stage, and the signals supplied to the first filter stage are the signals received by the base station antennas.  A cancellation stage cancels the obtained user signals received thereby from the received signals at a substantially same time with respect to the received signals.
Patent CA-2312483-A1 (CA)
Title: Data recording and reproduction apparatus
Inventor: INOUE MITSUHIRO
IPC: G11B20/00
Filed: 1999-10-08
Abstract: A data recording/reproducing device has a stream attribute judging means (101) for judging whether or not an audio data stream supplied from outside is compressed one, as shown in the figure. A compression identification flag Fco having a value corresponding to the judgment result is added to the audio data stream, and the resultant stream is recorded in a stream recording section (100b). Therefore, after a compressed audio data stream supplied from outside is read out of the stream recording section, an electronic watermark can be inserted in the data stream. Hence, the time taken to write a compressed audio data stream in the stream recording section is short, and degradation of the quality of sound of the analog audio data generated by reproducing the data stream is prevented.
Patent CA-2314905-A1 (CA)
Inventor: BRIDGES CHARLES R
IPC: A61K38/43
Filed: 1998-12-18
Abstract: Compositions, methods, kits and apparatus are provided for delivering a macromolecular assembly such as a plasmid, virus vector, or other gene vector, to an extravascular tissue such as muscle tissue. The composition comprises the macromolecular assembly and a vascular permeability-enhancing agent. In another embodiment, the composition further comprises a vasodilating agent.  The method of the invention comprises proving a vascular permeability-enhancing agent to a blood vessel and providing a macromolecular assembly to the vessel. An oxygenator useful for providing oxygen to a fluid extracorporeally prior to providing the fluid to a blood vessel of a mammal is included in the invention. Kits, apparatus, and methods for using the catheters described herein for isolating cardiac ciruclation, diverting caval blood flow from the right atrium, and other purposes, are also described.