baber/WOPTO huggingface dataset:
Patent JP-2002528117-A (JP)
Title: トランスジェニックおよびクローン哺乳動物
IPC: C12N5/10
Filed: 1999-11-02
Abstract: (57)【要約】
本発明は、クローン化されたトランスジェニック哺乳動物（例えばヤギ）を作成する方法に関する。本方法は、例えばドナー細胞として用い得る遺伝子導入体細胞株のような体細胞株を作成し、除核卵母細胞、好ましくは自然に成熟した終期卵母細胞に体細胞のゲノムを導入して再構成胚を形成させることによってクローン化されたトランスジェニック哺乳動物を作成し、および再構成胚を移植することを含む。また、本発明は、細胞株、再構成胚、およびクローン化されたトランスジェニック哺乳動物を包含する。
Patent JP-2002529057-A (JP)
IPC: G01N15/00
Filed: 1999-11-05
Abstract: The present invention concerns a system and a method for regulating the handling of milk during the milking process in order to separate mastitis infected milk from milk for human consumption and apt to be applied in an automated milking process.
Patent JP-2002531069-A (JP)
Title: タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用
IPC: G01N33/566
Filed: 1999-11-12
Abstract: (57)【要約】
  本発明は、カプサイシン／バニロイド受容体ファミリーの新規メンバーをコードするhVR-1、hVR-2及びrVR-2核酸分子と称する単離された核酸分子を提供する。本発明はまた、アンチセンス核酸分子、hVR-1、hVR-2及びrVR-2核酸分子を含有する組換え発現ベクター、該発現ベクターが導入されている宿主細胞並びにhVR-1、hVR-2及びrVR-2遺伝子が導入されているかまたは破壊されている非ヒトトランスジェニック動物も提供する。本発明はなおさらに、単離されたhVR-1、hVR-2及びrVR-2タンパク質、融合タンパク質、抗原性ペプチド並びに抗-hVR-1、抗-hVR-2及び抗-rVR-2抗体を提供する。本発明の組成物を利用する診断方法もまた提供される。
Patent JP-2002530643-A (JP)
IPC: G01N33/551
Filed: 1999-11-12
Abstract: A sensor apparatus and associated method for sensing and monitoring specific binding of analyte to an immobilized binding layer are disclosed. The apparatus preferably comprises an automatic critical angle refractometer having a linear scanned array and an optical system for illuminating a portion of the array, which illumination depends upon the refractive index of the binding layer deposited on an optically transparent element. The apparatus further includes a flow cell for bringing the analyte in contact with the binding layer. The apparatus also includes a computer for receiving and processing refractive index data from the critical angle refractometer during the reaction between the analyte and the layer, which computer may be peripherally connected to the refractometer or enclosed within the refractometer housing. A preferred sensing method of the present invention generally comprises providing a critical angle refractometer generating light impinging upon the immobilized binding layer, contacting the binding layer with a contacting phase, measuring the critical angle of total reflection, which measurements are indicative of the presence or absence of interactions between the analyte and the binding layer.
Patent JP-2002532485-A (JP)
IPC: C07D305/14
Filed: 1999-09-07
Abstract: Novel process for isolation of 14 beta -hydroxy 10-deacetyl baccatin-III (14 beta -OH-DAB) on a commercial scale from plant extract of Taxus species by solvent crystallization without employing chromatographic separation.
Patent JP-2002534758-A (JP)
Title: 高密度サーボトラック書込み用水平ローダ
IPC: G11B33/12
Filed: 1999-08-03
Abstract: (57)【要約】
この発明の一態様は、サーボトラック書込み処理中にディスクドライブ・ヘッドディスク組立体（ＨＤＡ）（１５２）を保持するための装置および方法に関する。このＨＤＡ（１５２）は、ベース、スピンドル軸（１３８）によってこのベースに回転可能に取付けたスピンドル（１３３）に結合したディスクスタック、およびピボット軸（１１８）でこのベースに枢動するように取付けたアクチュエータ組立体（１２０）を含む。このアクチュエータ組立体（１２０）のディスクスタックに近い一端に取付けてあるのは、これらのディスクから情報を読み／書きするための一つ以上の変換器である。この方法は、サーボトラック書込み中、このスピンドル軸（１３８）とピボット軸（１１８）の端を拘束する工程を含み、それでそれらの間の相対撓みが最小になる。即ち、これらの部品の回転運動以外の全ての運動を実質的に除去する。このスピンドル軸（１３８）とピボット軸（１１８）の端を拘束するための装置も提供する。この軸とスピンドルをそのように拘束することによって、これらの変換器が書込むサーボ情報がディスクの回転と同心であり、それでトラック位置ずれを減少し、最大トラック密度を改善する。
Patent JP-2003518325-A (JP)
Title: ダマシンによるメタリゼーション層を形成するためのリソグラフィックな方法
IPC: H01L21/768
Filed: 2000-01-06
Abstract: (57)【要約】
【課題】
【解決手段】  積層体内にメタリゼーション層を形成する改良された方法を開示する。本発明の１つの態様において、積層体に対してリソグラフィックなダマシンエッチングを実行し、金属配線を形成する方法が開示される。基板の上に配置された積層体は、１枚の下地層からなる。リソグラフィックなダマシンエッチングを実行する方法は、積層体の上にフォトレジスト層を堆積させる工程と、フォトレジスト層内にトレンチを形成することによって、トレンチを積層体の下地層上に位置決めする工程とを備える。この方法は、続いて、フォトレジスト層の上面上に金属層を堆積させて、トレンチを埋め込む工程と、金属層をフォトレジスト層の上面とほぼ同じ高さまで平坦化し、金属配線の上面を規定する工程と、金属配線の周りのギャップを残してフォトレジスト層を除去する工程とを備える。次いで、誘電材料を堆積させることによって、金属配線の周りのギャップを、金属配線の上面とほぼ同じ高さまで埋め込む。
Patent JP-2002535832-A (JP)
Title: キャッピング層を備える強誘電性デバイスおよびその作製方法
IPC: H01L21/02
Filed: 1999-10-15
Abstract: (57)【要約】
本発明は、集積回路用途の薄膜の分野に関し、特に、強誘電性薄膜に関する。より詳細には、強誘電性薄膜の性能を向上させる、特殊なキャッピング層に関する。強誘電性デバイス（１００）は、強誘電性層（１１２）および上部電極（１１６）を含む。強誘電性材料は、ペロブスカイトまたは層状超格子材料を原料とする。超格子ジェネレータの金属酸化物が、上記強誘電性層と上記上部電極との間にキャッピング層（１１４）として配置され、これにより、上記強誘電性層の残留分極容量が向上する。
Patent JP-2002537718-A (JP)
Title: 光学式Ａｄｄ／Ｄｒｏｐモジュールを有するネットワークノード
IPC: H04B10/213
Filed: 2000-02-08
Abstract: (57)【要約】
モジュールを接続の中断なしに交換することができるように、Ａｄｄ−Ｄｒｏｐ機能を２つのモジュール上に分割する。
Patent JP-2003535618-A (JP)
Title: 腹膜透析溶液の準備装置および方法
IPC: C02F1/68
Filed: 2000-03-03
Abstract: (57)【要約】
本発明は、乾燥または凍結乾燥された形態の腹膜透析液を貯蔵及び移送するため、並びに、それから提供可能な腹膜透析溶液を形成するための装置及び方法を提供する。一実施例において、腹膜透析に適した溶液を製造するためのシステム１０が提供される。図示されているように、精製された希釈液供給源１２は、試薬カートリッジ１４の上流に接続されている。カートリッジ１４は、チューブ１８を介して透析液リザーバー１６と液体伝達状態にある。精製された希釈液は、供給源１２から試薬カートリッジ１４に供給され、ここで乾燥した試薬が溶解し、腹膜透析溶液は、リザーバー１６に送られる。或いは、この溶液を、直接、腹膜腔に送ることができる。
Patent JP-2003507493-A (JP)
IPC: C08F210/16
Filed: 2000-03-28
Abstract: A process for producing high density polyethylene in the presence of a metallocene catalyst system in two liquid full loop reactors in series, wherein in a first reactor a first polyethylene product is polymerised substantially by homopolymerisation of ethylene and hydrogen, optionally with a minor degree of copolymerisation of ethylene with an alpha-olefinic comonomer comprising from 3 to 8 carbon atoms, and in a second reactor serially connected to the first reactor downstream thereof a second polyethylene product is copolymerised from ethylene and an alpha-olefinic comonomer comprising from 3 to 8 carbon atoms, and a hydrogenation catalyst is introduced into the reactants downstream of the first reactor.
Patent JP-2003528707-A (JP)
Title: プラズマ処置理方法及び装置
IPC: B01D53/72
Filed: 2000-04-27
Abstract: (57)【要約】
【課題】  汚染及び有毒な混合物の変換、不動態化、安定化のためのガスのプラズマ処理方法及び装置で表面のプラズマ処理を行うものを提供する。
【解決手段】  ガス圧力は１００トルを上回るものとする。処理ガス１は、逆極性の電極５を備える中空陰極２に通し、中空陰極放電プラズマ３を中空陰極２に接続しているジェネレーター４で発生させる。ガス１は、ガス中に発生している中空陰極放電プラズマ内で振動電子６との相互作用を経る。中空陰極の内壁８との中空陰極放電プラズマの相互作用を制御し、内壁温度は溶融点を下回るようにして、内壁を触媒として作用させる。内壁は、中空陰極放電プラズマ内でプラズマ化学反応を促進する壁構成物質９を放出可能とする。処理後にガスを変換ガス１０として排出し、表面処理に使用する。処理ガスを補助ガス７と混合して紫外線の放射やプラズマ化学反応を強め得る。
Patent JP-2002542853-A (JP)
IPC: A44C27/00
Filed: 2000-04-28
Abstract: A mesh jewel comprising a mesh formed by at least one metallic wire section (4) arranged along a mesh surface, wherein the mesh comprises nodes located at adjoining wire section parts of the at least one wire section (4). At least some of the nodes are formed with a node element (1) comprising a pin (2) arranged in cross direction to the mesh surface and structure for preventing displacement in an axial direction of the pin (2) of the wire section parts adjoining the pin (2) of the node element (1). The inventive method for manufacturing the mesh jewel comprises the steps of forming a mesh with at least one metallic wire section (4) by arranging it along a mesh surface, wherein the mesh comprises nodes at adjoining wire section parts of the at least one wire section (4). According to the invention, pins (2) are arranged in cross direction to the mesh surface, and the at least one wire section (4) is arranged so as to pass by the pins (2) and ends of the at least one wire section (4) are attached to the mesh jewel, wherein the pins (2) are fitted with structure for preventing displacement in an axial direction of the pins (2) of the wire section parts adjoining the pins (2).
Patent JP-2002544213-A (JP)
IPC: A23K1/18
Filed: 2000-04-17
Abstract: The present invention relates to a composition containing the natural substances carvacrol and thymol. The amount of carvacrol is 5 ppm to 90% by dry weight, the amount of thymol is 5 ppm to 80% by dry weight, and the weight ratio between carvacrol and thymol is from 1:5 to 10:1. The composition exhibits a synergistic bactericidal effect against Treponema which causes severe muco-hemorrhagic diseases, such as swine dysentery and severe diseases affecting the hoofs of hoofed animals, particularly cloven-hoofed animals, such as ruminants. The composition is suitably administered to an animal via the diet or via the drinking water or via a drench bath.
Patent JP-2003500951-A (JP)
Title: 可変チャネルローディング式セルラー通信システム
IPC: H04W16/14
Filed: 2000-05-10
Abstract: (57)【要約】
時分割多元接続プロトコルに従って動作するセルラー無線通信システムは、種々のフラクショナル・ローディングフ率を異なるタイムスロットに割り当てる手段を有する。その結果と、それに加えてローカル伝搬条件の影響のため、異なるタイムスロットは異なる干渉レベルを有する。移動局がセルの端にあるとき、或いは、激しいシャドウフェージングを受けるときのように最悪ケースの伝搬環境における移動局は、低干渉レベルのタイムスロットが割り当てられる。一方、良好な伝搬環境にある移動局はより高い干渉レベルのタイムスロットが割り当てられる。本発明によれば、好ましくない伝搬環境におけるサービス品質が改良される。
Patent JP-2002206622-A (JP)
Title: Hydraulic continuously variable transmission
Inventor: MOCHIZUKI YASUHISA
IPC: F16H57/023
Filed: 2001-01-09
Abstract: PROBLEM TO BE SOLVED: To facilitate the assembly of a housing 20 with a center section 5 in a hydraulic continuously variable transmission 1 comprising an output shaft 32 pivotally supported on bearing hole parts 20b and 5b formed in the housing 20 and the center section 5, a cylinder block 33 having the output shaft inserted therein and rotated together with the output shaft 32, an internal spring type plunger 34 slidably inserted into the cylinder block 33, and a fixed swash plate 35 in contact with the plunger 34. SOLUTION: An elastically deformable projected part is provided on the inner peripheral surface of the bearing hole part 20b in the housing 20, and a groove part is provided in the front end part outer peripheral surface of the output shaft 32. The front end part of the output shaft 32 is inserted into the bearing hole part 20b to engage the projected part with the groove part and, after the axial movement of the output shaft 32 is restricted, the housing 20 is assembled with the center section 5.
Patent JP-2002206498-A (JP)
Title: Air quantity control system for ventilation fan
Inventor: TOKUNAGA MASAHIKO
IPC: F04D29/44
Filed: 2001-01-10
Abstract: PROBLEM TO BE SOLVED: To provide an air quantity control system for a ventilation fan capable of preventing clogging of a pilot duct due to oil and fat, capable of preventing lowering of energy-saving efficiency, and capable of stabilizing the capacity. SOLUTION: This air quantity control system for the ventilation fan is provided with a plurality of branch ventilation ducts 1a, 1b and 1c for carrying the polluted air including oil and fat, a main ventilation duct 3 connected to the downstream end of each branch ventilation ducts 1a, 1b and 1c, to unify the branch ventilation ducts 1a, 1b and 1c, a ventilation fan 5 provided in the downstream end of the main ventilation duct 3 to discharge the polluted air from the main ventilation duct 3, a pilot duct 7 connected to the upstream end 3a of the main ventilation duct 3 and having a terminal opened in the atmospheric space 8 which does not contain dirt such as oil and fat, a wind speed sensor provided inside of the pilot duct, and a control means 14 for controlling the air quantity of the ventilation fan 5, on the basis of the wind speed obtained by the wind speed sensor.
Patent JP-2002208707-A (JP)
Title: Method of manufacturing thin-film transistor
Inventor: AZUMA SEIICHIRO
IPC: H01L21/20
Filed: 2001-01-10
Abstract: PROBLEM TO BE SOLVED: To provide a thin-film transistor which has high mobility, low threshold voltage and less variations by lowering the capture level of a semiconductor layer formed by a low-temperature process as well as MOS boundary. SOLUTION: Light is radiated onto a semiconductor layer 103 on a substrate 101 at 100 deg.C or lower in substrate temperature for crystallization, and then the semiconductor layer 103 is treated by a plasma at 100 deg.C or lower in substrate temperature. Furthermore, a gate insulation film 105 is formed on the semiconductor layer 103 at 100 deg.C or lower in substrate temperature, and it is heated at 100 deg.C or higher.
Patent JP-2002208202-A (JP)
Title: Disk clamping device
Inventor: WATANABE TAKASHI
IPC: G11B17/028
Filed: 2001-01-10
Abstract: PROBLEM TO BE SOLVED: To prevent the inner peripheral side of a disk from being deformed by clamping force. SOLUTION: In a disk clamping device 23, the inside diameter of a friction member 42 fixed on a disk placing surface 18a of a clamping table 18 is extended to the inner side so that it has a diameter almost equal to the inside diameter of a disk 22. A flange part 34a projecting in a radial direction from the outer periphery of a clamper top 34 is extended under the innermost periphery part of the friction member 42. The upper surface of the flange part 34a is provided at a position with a height which is the same level as the disk placing surface 18a. Accordingly, the friction member 42 is placed in a flat state without ruggedness from the position opposed to the innermost periphery part of the disk 22 to near the outer periphery of disk placing surface 18a.  Accordingly, even if the tip parts 38a1 to 38e1 of clamping members 38a to 38e press the inner periphery edge of the disk 22 diagonally downward by the spring force of a coil spring 36, the downward deformation of the inner periphery edge of the disk 22 is prevented.
Patent JP-2002209317-A (JP)
Title: Communication cable laying channel in sewer pipe, jig for constructing the communication cable laying channel, and communication cable laying method using the jig
Inventor: OKA KATSUMI
IPC: H02G9/06
Filed: 2001-01-10
Abstract: PROBLEM TO BE SOLVED: To develop a laying mode of a communication cable which enables a communication cable to be easily laid and to improve the service life of the communication cable as a communication infrastructure. SOLUTION: A communication cable laying channel 1 for the communication cable is constituted of a solidified material of a hardening agent 9 which is fixed and hardened on the inner surface of a sewer pipe 2 of the communication cable of a cable guide 10 in such a manner that the communication cable or the cable guide 10 extending along the sewer pipe 2 is supported. A laid cover 4 is inserted in the sewer pipe 2 and made to abut against the inner surface of the sewer pipe 2, and a hollow path is constituted. In a state with the communication cable or the cable guide 10 inserted in the hollow path, the hardening agent 9 is injected. Using the hardening agent 9 which is fixed on the inner surface of the sewer pipe 2 and hardened, the communication cable or the cable guide 10 is supported and laid additionally on the inner surface of the sewer pipe.
Patent JP-2002205112-A (JP)
Title: Method for forming multi-space pipe
Inventor: KAWAI KANJI
IPC: F28F1/02
Filed: 2001-01-11
Abstract: PROBLEM TO BE SOLVED: To provide a multi-space pipe formed of copper, etc., to allow water, etc., to be used for the coolant flowing in the multi-space pipe. SOLUTION: A method for forming the multi-space pipe 10 with an internal space thereof partitioned into a plurality of spaces by partitioning walls 12 extending in the longitudinal direction comprises a step of preparing a pipe 101 having projecting bars 12t extending in the longitudinal direction formed on an inner circumferential surface, and a step of forming the partitioning walls 12 of the projecting bars 12t.
Patent JP-2002206787-A (JP)
Title: Air conditioner
Inventor: KAMIDOEN TOSHIRO
IPC: F24F1/02
Filed: 2001-01-12
Abstract: PROBLEM TO BE SOLVED: To prevent a compressor from becoming overloaded when the operation of an air conditioner is switched from operation wherein an airflow direction changing body is pivoted from a position whereat the same is closing an air outlet port, into other operation wherein the airflow direction changing body is stopped. SOLUTION: The airflow direction changing body for dehumidifying suction air from an air suction port 15 and sending out the same to the outside of a main body case 5 from an air outlet port 16 while opening and closing substantially whole of the air outlet port 16, is constituted of a first airflow direction changing body 20, provided by a motor driving means 44, and a second airflow direction changing body 21, provided manually, while a microcomputer 3 for controlling a position detecting means 45, detecting the position of the first airflow direction changing body 20, a stopping means for stopping the pivoting of the first airflow direction changing body 20 and a motor driving means 44, is provided.  When the operation is switched by a mode switching switch 9 into a stopping mode S4 when the position detecting means 45 is detecting that the position of the first airflow direction changing body 20 is positioned within a predetermined position B from the position A of closed condition, the microcomputer 43 pivots the first airflow direction changing body 20 to the predetermined position B to stop the pivoting of the same.
Patent JP-2001332658-A (JP)
Title: Semiconductor integrated circuit device and manufacturing method therefor
Inventor: MIYAMOTO TOSHIO
IPC: H01L23/485
Filed: 2001-01-12
Abstract: PROBLEM TO BE SOLVED: To provide a semiconductor integrated circuit device and its manufacturing method where a metallic circuit and a protecting film also used as a guide for the metallic circuit can precisely be formed at a comparatively simple step. SOLUTION: Resin at a periphery of a metallic circuit forming region which is extended from the electrode BP prior to rearrangement to a bump electrode contacting region BA is hardened by radiating and scanning a laser beam 5 to a photo hardening resin layer which is formed on the electrode BP prior to rearrangement. After a hardened resin 6 which is the protecting film used also as the metallic guide which is an empty part of the metallic circuit forming region, the metallic circuit is formed inside the hardened resin 6.
Patent JP-2002206615-A (JP)
Title: Feed screw device
Inventor: WATANABE TAKASHI
IPC: F16H25/20
Filed: 2001-01-12
Abstract: PROBLEM TO BE SOLVED: To provide a feed screw device which can moderate a shock in a drive end by supporting both end parts of a feed screw to freely move through a buffer member to absorb inertia force of the feed screw, after a moving member moved by it collides against a stopper, by moving the feed screw in an axial direction. SOLUTION: This feed screw device 70, when a guide part 84 abuts to a stopper 88 to position a projection lens mirror barrel 14 in the upper end of a moving stroke, stops not a motor 74 but upward movement of the projection lens mirror barrel 14, to be placed in a condition of rotation. Drive force of the motor 74 is transmitted to continue to a feed screw 72, but it is regulated with upward movement of a nut member 82, so that moved force in a downward direction is given from the motor 74. The feed screw 72 is moved downward against energizing force of a spring 76. By this action, impact force, when the guide part 84 abuts on the stopper 88, is moderated.
Patent JP-2002216690-A (JP)
Title: Method and device for controlling charged beam
Inventor: HASHIMOTO SUSUMU
IPC: H01J37/12
Filed: 2001-01-22
Abstract: PROBLEM TO BE SOLVED: To provide a method and device for controlling charged electron beam at high precision where blurring caused by optical aberration and shape/ dimension error of electron beam caused by polarization are corrected. SOLUTION: A charged beam 2 is controlled by controlling a voltage to electrodes according to a polarized charged beam condition using a rotation- symmetry round type electron lens 16 capable of independently controlling the control voltages, in the middle of orbit of the charged beam 2 passing a multi-pole field formed with pole lenses 11, 12, 18 and 19.
Patent JP-2002214178-A (JP)
Title: Concentration measurement and management method for water treatment chemical, and device therefor
Inventor: UDAGAWA ATSUSHI
IPC: G01N27/10
Filed: 2001-01-22
Abstract: PROBLEM TO BE SOLVED: To provide a concentration measuring method and a management method for water treatment chemical capable of rapidly and precisely performing the measurement of effective component concentration in the water of a water treatment system and also monitoring it, and a device therefor. SOLUTION: In this concentration measurement method and management method for water treatment chemical and the device therefor, in the measurement of the concentration of a water treatment chemical in the water treatment system, a sample containing the water treatment chemical is oxidized, and the difference between the electric conductivity before oxidation of the sample and the electric conductivity after oxidation thereof is detected by use of a differential conductivity gauge comprising electric conductivity measuring cells having at least two electrodes arranged in the position before oxidation and the position after oxidation, which outputs the difference between the own detection signals from both the electric conductivity measuring cells as the difference in electric conductivity of the sample between both the electric conductivity measuring cell positions,  whereby the electric conductivity increase caused by the oxidation decomposition of the water treatment chemical is measured, and the concentration of the water treatment chemical in the sample is quantitatively determined from the electric conductivity increase.
Patent JP-2002217969-A (JP)
Title: Method and device for relaying data
Inventor: OGUCHI KAZUMI
IPC: H04L47/32
Filed: 2001-01-23
Abstract: PROBLEM TO BE SOLVED: To realize a cell disposition controlling process for coping with inputting of excessive traffic into a buffer with a simple means, in which cell disposition between connections or between input lines is performed in a fair manner. SOLUTION: A disposition start threshold setting part 5 sets an in-buffer cell accumulated amount, with which a cell disposition part 4 starts disposing of cells, as the disposition start threshold. A disposition-cancel threshold setting part 6 sets an in-buffer cell accumulation amount with which the cell disposition part 4 stops disposing cells, as a disposition-cancel threshold, with disposition- start threshold being>disposition-cancel threshold. An accumulation-amount measuring part 7 measures accumulated amount of cells in the buffer. The cell disposition part 4 disposes cells, when the in-buffer cell accumulation amount reaches the disposition-start threshold, and cancels disposing of cells when the in-buffer cell accumulation amount reaches the disposition-cancel threshold, for a cell to be written into a buffer 1.
Patent JP-2002211164-A (JP)
Title: Method and apparatus for bookbinding booklet
Inventor: ASANO HIDEO
IPC: B42C19/08
Filed: 2001-01-23
Abstract: PROBLEM TO BE SOLVED: To enable a saddle stitching double folding booklet to be efficiently bookbound from a plurality of continuous sheets printed by a rotary press. SOLUTION: A method for bookbinging the booklet comprises the step of bookbinding a double folding the booklet from the plurality of continuous sheets printed by the rotary press. The method further comprises a gathering step 2 of the gathering the plurality of continuous sheets folded in a zigzag manner printed by the rotary press, a binding step 6 of binding the double folding parts to become the book, a cutting step 11 of removing back edges of the gathered continuous sheets, cutting the continuous sheets in size of the booklet in a running direction and discharging the booklet in a two-page spread state, a folding step 15 of folding at least the booklet of the two-page spread state at the bound part in at least the binding step,  a pressurizing step of pressurizing the folded booklet and the step of sequentially continuing the pressurized step from the gathering step to bookbind the booklet.