baber/WOPTO huggingface dataset:
Patent CA-2453613-A1 (CA)
Title: Sulfonyl aryl hydroxamates and their use as matrix metalloprotease inhibitors
Inventor: BECKER DANIEL P
IPC: C07D207/14
Filed: 2002-07-19
Abstract: The invention is directed to sulfonyl aromatic hydroxamic acid compounds and salts thereof that, inter alia, inhibit matrix metalloprotease (MMP) activity and/or aggrecanase activity. In some particularly preferred embodiments, the compound corresponds in structure to one of the following formulas: (I) (II) wherein W2, the R groups, and -A-R-E-Y are described in more detail in Applicants'specification. This invention also is directed to a process that comprises administering such a compound or pharmaceutically acceptable salt thereof to a host animal having a condition associated with MMP activity.
Patent CA-2453659-A1 (CA)
Inventor: CORNELISSEN ERIK KERST
IPC: E21B33/12
Filed: 2002-07-18
Abstract: A method is provided for activating a downhole system arranged in an annular space formed between a radially expandable tubular element extending into a borehole formed into an earth formation and a cylindrical wall surrounding t he tubular element. The downhole system is arranged so as to be activated by movement of an annular movement device along the tubular element. The method comprises arranging said annular moving device around the tubular element, t he moving device having an inner diameter slightly larger than the outer diamet er of the tubular element in its unexpanded shape, and gradually expanding a portion of the tubular element by moving an expander through the tubular element in the direction of the moving device, whereby a transition zone of the tubular element is defined between the expanded an unexpanded portions o f the tubular element. Upon contact of the transition zone with the moving device, continuing movement of the expander through the tubular element caus es the moving device to move in axial direction along the tubular element where by the moving device activates the downhole system.
Patent CA-2454251-A1 (CA)
Inventor: RAFII SHAHIN
IPC: A61K35/12
Filed: 2002-08-12
Abstract: L'invention concerne des procédés d'isolation de cellules souches mammifères exprimant le récepteur VEGFR-1 et des compositions de celles-ci. L'invention concerne également des procédés d'utilisation de telles cellules souches mammifères exprimant VEGFR-1, aux fins de traitement de divers états, notamment l'hématopoïèse, la vasculogénèse et/ou l'angiogénèse, la myogénèse et la neurogénèse, aux fins de traitement de divers états. L'invention concerne enfin des méthodes thérapeutiques mettant en oeuvre une molécule liant et activant ou stimulant VEGFR-1, par exemple, P1GF, aux fins de stimulation de la prolifération et/ou différentiation et de la mobilisation, c'est-à-dire, la motogénèse, de cellules souches.
Patent CA-2457554-A1 (CA)
Title: Screen system
Inventor: BAILEY MARSHALL GRAHAM
IPC: B07B1/49
Filed: 2002-08-12
Abstract: The present invention provides a screen system (8) suitable for use in a vibratory screen apparatus (1), and comprising: a screen element (11) and a support frame (12) therefor, as well novel screen elements (11) and mesh panels (19) therefor, and the use thereof. The screen element (11) consists essentially of a mesh panel (19) provided with first and second elongate support members (22, 23) extending along opposite end portions of the mesh panel (19). The support frame (12) has spaced apart first and second elongate frame elements (13, 14) for engagement with the screen element support members (22, 23) and further elongate frame elements (17, 18) extending there between for supporting the mesh panel (19). The screen element support members (22, 23) and said first and second frame elements (13, 14) are formed and arranged for secure interengagement in use of the screen system, with at least one of said screen element support members and the respective one of said first and second frame elements being formed and arranged so that when clamped together, the mesh panel (19) is securely held under tension against said further frame elements (17, 18).
Patent CA-2458878-A1 (CA)
Inventor: SCHAEFER MARK DONALD
IPC: F02B63/02
Filed: 2000-01-13
Abstract: A four-stroke internal combustion engine (20) is provided. There is provided within an engine housing (28) an oil reservoir (126) and a valve chamber (156) which independently communicate with a crank chamber (124). A strategically placed divider (116) and passageway, located within the engine housing (28), appropriately direct lubricant within the engine housing (28) so that the internal cavity of the engine is lubricated during use in various operating attitudes, and so that the fluid flows to and is held in the proper chambers of the engine housing during storage. There is also provided a breather arrangement for an internal combustion engine (20) which includes a cam shaft (98) having a hollow passageway in communication with the crank chamber (124) and the air intake system of the engine. There is also provided an engine housing which can be utilized for engines having different horse power ratings. There is also provided a crankshaft bearing assembly (68, 70) which prevents damage to the bearing upon insertion of the crankshaft (80) into the crank chamber (124).
Patent CA-2459261-A1 (CA)
Title: Apparatus and system for concentrating slurry solids
Inventor: PALMER ROBERT M
IPC: B01D21/26
Filed: 2004-03-02
Abstract: An apparatus to separate solids from drilling slurry, having an inlet positioned over an outlet of a concentration tank to displace water that would otherwise enter the down-stream centrifuges. Baffles are provided to direct solids to the outlet and minimize the time that solids spend in the concentration tank. Fluids having solids removed therefrom are removed from the apparatus at a location remote from the outlet
Patent CA-2461806-A1 (CA)
Inventor: KITAMURA TAKAHIRO
IPC: A61K31/50
Filed: 2002-09-25
Abstract: Compounds represented by the following general formula (1), which have an effect of inhibiting IL-.beta. production, are highly soluble in water and have a favorable oral absorbability, and medicinal compositions containing the same: (1) wherein R1 represents alkyl, alkenyl, etc.; R2 and R3 represent each hydrogen, alkyl, hydroxyalkyl, dihydroxyalkyl or alkynyl, or R2 and R3 may form together with the adjacent nitrogen atom an optionally substituted nitrogen-containing saturated heterocyclic group; X, Y and Z represent each hydrogen, alkyl, halogeno, etc.; and n is from 1 to 5.
Patent CA-2463033-A1 (CA)
Title: Radial piston hydraulic motor and method in the control of a radial piston hydraulic motor
Inventor: LAMPINEN MIKA
IPC: F04B1/04
Filed: 2004-03-31
Abstract: The invention relates to a radial piston hydraulic motor (100) and to a method in the control of a radial piston hydraulic motor. The radial piston hydraulic motor (100) includes a free rotation valve (50) which is built inside it and includes a spindle (19). The spindle (19) is disposed in a spindle cavity (20) and it is movable in the spindle cavity (20) such that, in a free rotation situation, shoulders of the spindle (19) block the inlet and outlet passages of working pressure. In a free rotation situation, springs (U1, U2...) press pistons (13a1, 13a2...) and press rollers (14a1, 14a2...) associated therewith to a bottom position and out of contact with a cam ring (11).
Patent CA-2463600-A1 (CA)
Title: Device and method for ultrasound wound debridement
Inventor: BABAEV EILAZ
IPC: A61B19/00
Filed: 2003-08-04
Abstract: An end-effector configured and dimensioned for being connected to an ultrasound surgical device is provided. The end-effector includes means for receiving ultrasound waves generated and propagated by the ultrasound surgical device, and means for debriding tissue on a wound surface. The means for debriding tissue includes at least one non-smooth surface; and means for propagating the received ultrasound waves to the at least one non-smooth surface for vibrating the at least one non-smooth surface, wherein the at least one non-smooth vibrating surface is configured to contact and debride tissue on the wound surface. A method is further provided for debriding wound tissue including the steps of providing ultrasound waves to a non~smooth surface configured for debriding, propagating the ultrasound waves to cause vibration of the non-smooth surface, and contacting the vibrating surface configured for debriding with the wound tissue.
Patent CA-2465946-A1 (CA)
Inventor: KORNELSON BRENT A
IPC: G05G9/047
Filed: 2004-04-30
Abstract: L'invention porte sur une manette de jeu constituée d'une poignée, d'un manche possédant des extrémités supérieure et inférieure opposées ainsi que d'un boîtier curviligne. La poignée est montée sur l'extrémité supérieur du manche. L'extrémité inférieure du manche est fixée dans le boîtier curviligne. Le boîtier curviligne possède une surface extérieure curviligne fabriquée de sorte à inclure au moins une surface d'appui dans une zone généralement sphérique située entre deux plans horizontaux parallèles. Cette zone comprend une portion de la section sphérique possédant une circonférence maximale faisant en sorte qu'il est possible de fixer en place le boîtier curviligne à l'aide de la surface d'appui. Un dispositif de fixation amovible composé d'au moins deux éléments de serrage peut être serré de manière non permanente, à l'aide d'organes de fixation amovibles sur la surface d'appui, le long de l'interface des éléments de serrage de façon à supporter l'ensemble et à se fixer entre les deux éléments, à l'endroit où se trouve la circonférence maximale de la section sphérique.
Patent CA-2468534-A1 (CA)
Title: Zeolite catalysts for transalkylation of diisopropylbenzol
Inventor: MEIMA GARMT R
IPC: B01J35/00
Filed: 2002-10-07
Abstract: The present invention disclosed a catalyst composition comprising a dealuminated mordenite component together with a second zeolite which has a 12 membered ring in the acidic form. The catalyst has particular utility in the process for transalkylating dialkylated benzene to form cumene,
Patent CA-2469264-A1 (CA)
Inventor: BERGMAN RICHARD
IPC: E02D27/00
Filed: 2004-05-17
Abstract: A post anchoring device for anchoring posts used in fence, deck, balcony and railing applications to a surface, the device comprising a base member capable of being connected to the surface, and an elongate, preferably cylindrical, tubular member having a base end and a terminal end, the base end being connected to the base member and the terminal end being remote from the base member such that the post may be impaled upon the tubular member by a user. The walls of the tubular member at the terminal end may be beveled to provide a cutting edge for cutting into the post to facilitate the impalement of the post. The base member may include a peripheral flange with a peripheral edge for abutting the end of the post thereby defining a cavity in which fasteners or other hardware may be concealed from sight for an aesthetically pleasing result.
Patent CA-2470763-A1 (CA)
Inventor: ZIESCHE ROLF
IPC: A61P37/02
Filed: 2002-12-12
Abstract: La présente invention se rapporte à une nouvelle composition pharmaceutique comprenant l'interféron-.gamma. ou un pirfénidone ainsi qu'un ensemble diagnostic de polynucléotides candidats et permettant d'améliorer le traitement des affections pulmonaires, notamment de toutes les formes d'affections pulmonaires interstitielles. L'invention se rapporte à la combinaison du diagnostic moléculaire et de la thérapie clinique en tant que nouveau principe de médication pour la réduction de la mortalité et l'amélioration de la gestion thérapeutique des affections pulmonaires interstitielles.
Patent CA-2474285-A1 (CA)
Title: Vegetation pruning device
Inventor: JARMAN DAVID
IPC: B27B17/08
Filed: 2004-07-13
Abstract: A vegetation pruning device (2) includes a shear arrangement comprising a pair (4,6) of pivotally coupled arms. A motor bracket (36) with a rotary output drive (34) provides drive to a cutting element (8) which is coupled to the rotary output drive (34). The cutting element (8) is arranged for cutting vegetation (44) presented thereto.
Patent CA-2475421-A1 (CA)
Title: Structure comprenant un polymere fluore modfie et electrode a base de cette structure
Inventor: PASCAL THIERRY
IPC: C09D127/16
Filed: 2004-07-28
Abstract: La présente invention concerne une structure comprenant successivement: .cndot. une couche d'un métal L1, éventuellement un primaire fluoré L2 qui est un mélange comprenant en poids 1 à 100% d'au moins un polymère fluoré modifié pour respectivement 0 à 99% de polymère fluoré, et une couche d'un polymère fluoré L3, .cndot. telle que si la couche de primaire L2 est absente alors le polymère fluoré L3 est un mélange comprenant en poids 1 à 100% d'au moins un polymère fluoré modifié pour respectivement 0 à 99% de polymère fluoré, .cndot. ledit polymère fluoré modifié étant choisi parmi: ~ les polymères fluorés greffés par un monomère insaturé, le greffage étant effectué en l'absence d'oxygène par irradiation du monomère insaturé et du polymère fluoré préalablement mélangés à l'état fondu, ~ les polymères fluorés irradiés en présence d'oxygène (aussi désignés par polymères fluorés oxydés). Selon une forme particulière la structure dé l'invention est une électrode d'une batterie lithium-ion dans laquelle le métal L1 est le collecteur et le polymère fluoré L3, fortement chargé de carbone et/ou d'oxydes, en est la couche électroactive.
Patent CA-2475887-A1 (CA)
Inventor: CREAGER CHRISTOPHER WAYNE
IPC: B60K15/04
Filed: 2004-07-28
Abstract: A tubular poppet type check valve for a fuel tank filler tube having annular barbs on the inlet end for snap-in attachment in a non-metallic tank spud and provisions for push-in connection with the end of a metallic spud which is crimped over a groove. The poppet has an annular groove with an overmolded elastomeric seal formed preferably with a wiper portion for facilitating sealing on a valve seat. The poppet has a post portion slidably guided in an aperture in the closure provided in the downstream of the valve. A slot in the side of the valve body allows a siphon hose inserted in the inlet to exit the valve and feed through to the bottom of the tank. Deflector vanes are provided in the inlet end to direct a siphon hose to the outlet slot. The poppet has turbulence reducing vanes on the upstream side.
Patent CA-2477849-A1 (CA)
Inventor: ALTHOEFER HENNING
IPC: C12N5/10
Filed: 2003-02-28
Abstract: The invention relates to transcription terminators, to an organism containing at least one of these transcription terminators, and to a method for producing riboflavin. According to the invention, an organism is grown, which is capable of producing riboflavin and has at least one of these transcription terminators, whereby the respective transcription terminator is operatively linked to at least one rib gene.
Patent CA-2481753-A1 (CA)
Inventor: FINK MITCHELL P
IPC: A61K47/12
Filed: 2003-04-17
Abstract: L'invention concerne un procédé permettant de traiter un iléus chez un sujet. Ce procédé comprend l'étape consistant à administrer au sujet une quantité efficace d'un acide alpha-cétoalcanoïque, d'un sel acceptable au niveau physiologique d'une acide alpha-cétoalcanoïque, d'un ester d'un acide alpha-cétoalcanoïque, ou d'un amide d'un acide alpha-cétoalcanoïque.
Patent CA-2481776-A1 (CA)
Inventor: JALBERT RAYMOND M
IPC: G06F17/00
Filed: 2004-09-16
Abstract: Méthode permettant de recueillir des données auprès dun client, par un mécanisme de collecte de données. La méthode comprend la collecte, auprès dun client, dune première partie de données, par un premier mécanisme de collecte de données, à laide dau moins une partie dun premier script comprenant une ou plusieurs demandes dinformation présentées au client. De plus, la méthode comprend le fait dassocier le client à un deuxième mécanisme de collecte de données en se fondant, en partie, sur un événement associé à linteraction du client avec le premier mécanisme de collecte de données. Après avoir associé le client au deuxième mécanisme de collecte de données, il convient de recueillir auprès du client une deuxième partie des données à laide dun deuxième script, ledit deuxième script comprenant au moins une demande dinformation pas encore présentée au client dans le premier script.
Patent CA-2482767-A1 (CA)
Title: Reagents for monitoring nuclei acid amplification and methods of using same
Inventor: LAWLER JOSEPH F JR
IPC: C12Q1/68
Filed: 2003-04-09
Abstract: Described herein are novel indicator molecules of general formula (I): wherein Q, F ,N, Nuc, X1 and X2 are as defined herein, including their tautomeric forms and their additive salts. The present invention also concerns methods for the use of these molecules to monitor nucleic acid amplificationin real time their applications as diagnostics.
Patent CA-2485245-A1 (CA)
Title: Method and apparatus for encoding/decoding broadcast or recorded segments and monitoring audience exposure thereto
Inventor: AIJALA VICTOR A
IPC: H04H60/31
Filed: 1993-11-16
Abstract: Methods and apparatus for encoding and decoding information in broadcast or recorded segment signals are described. In certain embodiment, an audience monitoring system encodes identification information x(w) in the audio signal portion of a broadcast or recorded segment using spread spectrum encoding. A personal monitoring device receives an acoustically reproduced version of the broadcast or recorded signal via a microphone, decodes the identification information from the audio signal portion despite significant ambient noise and stores this information, automatically providing a diary for the audience member which is later uploaded to a centralized facility. A separate monitoring device decodes additional information from the broadcast signal, which is matched with the audience diary information at the central facility. This monitor may simultaneously send data to the centralized facility using a dial-up telephone line, and receive data from the centralized facility through a signal encoded using a spread spectrum technique and modulated with a broadcast signal from a third party.
Patent CA-2485656-A1 (CA)
Title: Device for the transdermal administration of a rotigotine base
Inventor: BREITENBACH ARMIN
IPC: A61K31/381
Filed: 2003-12-24
Abstract: The invention relates to a polymer matrix suitable for the transdermal administration of rotigotine [(-)-5, 6, 7, 8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphtol], containing a matrix for the transdermal administration of rotigotine [(-)-5, 6, 7, 8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1naphtol], containing a matrix polymer which is supersaturated with a rotigotine base. Said polymer matrix is characterised in that the part of the rotigotine which is not dissolved in the matrix polymer is dispersed in the matrix polymer as amorphous particles having a maximum mean diameter of 30 m, and the matrix is free of solubilisers, crystallisation inhibitors and dispersants. The invention also relates to a flat device for the transdermal administration of rotigotine, containing the above-mentioned, preferably silicon-based polymer matrix which is supersaturated with rotigotine, and a rear layer which is impermeable to the active ingredient.
Patent CA-2485666-A1 (CA)
Title: Two-mode therapeutic mattress system
Inventor: O'REAGAN JAMES RICHARD
IPC: A47C27/18
Filed: 2004-10-21
Abstract: A two-mode therapeutic mattress system is provided, including a non-powered air mattress, a pressure dispersion cushion, and a selectively operable air diffusion coverlet in a common modular assembly for improved medical management of skin care. The non-powered air mattress includes longitudinal air cylinders providing a static air support system inflated to predetermined pressure. The longitudinal air cylinders are in pressure communication with elasticized reservoirs, in that the air level in the elasticized reservoirs dynamically reacts to changes in pressure in the longitudinal air cylinders, for example upon receipt of a patient upon the mattress system. The pressure dispersion cushion facilitates pressure relief with a number of lateral and longitudinal cuts resulting in a plurality of separate upright support cells, the size and construction of which may vary over the surface of the pressure dispersion cushion so as to provide selective support characteristics. The air diffusion coverlet contains a plurality of air pockets. The air diffusion coverlet operates in two modes: a "therapy mode" such that compressed air from an air compressor is pumped to the air diffusion coverlet, and an "off' mode in which the air pockets collapse to provide a suitable and relatively smooth bedding component to the therapeutic mattress system.     The non-powered air mattress, pressure dispersion cushion, and selectively operable air diffusion coverlet cooperate to provide a single product that addresses localized pressure, maceration, shear stress, and dynamic changes in a patient's condition during the course of time.
Patent CA-2486005-A1 (CA)
Title: Drug container entry mechanisms and method
Inventor: HICKLE RANDALL S
IPC: A61M39/28
Filed: 2003-05-16
Abstract: The invention of this application relates generally to intravenous (IC) infusion of drugs to patients, and more particularly to aspects of an IV  infusion system comprising an infusate cassette and an infusate container. The present invention provides a drug infusion cassette (150) that incorporates a strong vial spike (163) that may be non-metal, a means for sheathing (158) the spike when it is not in use, an anti-free flow device (168), and other beneficial features such as an air entrainment lockout mechanism, quality assurance tags, stopcocks made of soft material and means of securing tubing to the cassette with a minimum of individual parts. The drug cassette (150) can be used with an automated spiking mechanism comprising a motorized vial holder that holds a vial. The spike (163) remains sheathed if the drug cassette (150) is not fully engaged with a mating surface (200) of devices such as a pumping unit or a sedation and analgesia delivery system.
Patent CA-2487720-A1 (CA)
Title: Therapeutic agent-containing polymeric nanoarticles
Inventor: DECOR RACHEL
IPC: A61K47/48
Filed: 2003-06-03
Abstract: Hydrophilic polymeric articles comprising a polymeric scaffold and one or mo re therapeutic agents, such as drug or drug-conjugate molecules. The articles m ay further optionally comprise recognition elements (REs) that bind to biomolecular structures expressed on certain cells or in certain tissues, to facilitate targeting and/or delivery.
Patent CA-2487986-A1 (CA)
Inventor: VAN HANDEL GERALD J
IPC: B65D43/16
Filed: 2003-06-06
Abstract: L'invention concerne un ensemble (10) de récipients (12, 14, 16, 54, 56, 58) interconnectés, séparables et formés d'une seule pièce et leurs couvercles associés (106, 108, 110, 188, 190, 192), lesdits récipients étant conçus pour être utilisés comme récipients jetables destinés à des condiments, des sauces et analogues. Ledit ensemble interconnecté comprend en général une première pluralité de récipients (12, 14, 16) agencés en un premier ensemble linéaire (17) et une seconde pluralité de récipients (54, 56, 58) agencés en un second ensemble linéaire (59), les premier (17) et second ensembles linéaires (59) étant fixés l'un à l'autre à l'aide d'une pluralité de parties de déchirement (96, 98, 100). Des première et seconde pluralités de couvercles sont articulés aux récipients et disposés vers l'extérieur par rapport à ceux-ci de sorte que les couvercles et les récipients s'équilibrent pendant une opération de remplissage.
Patent CA-2493236-A1 (CA)
Title: Apparatus and method for inputting data
Inventor: MONTELLESE STEVEN
IPC: G06F3/033
Filed: 2003-01-23
Abstract: An input device (10) for detecting input with respect to a reference plane (24). The input device (10) includes one or more light sensors (16,18) positioned to sense light at an acute angle with respect to the reference plane (24) and for generating a signal indicative of sensed light, and a circuit (20) responsive to said light sensor for determining a position of an object with respect to the reference plane (24).