baber/WOPTO huggingface dataset:
Patent HU-207230-B (HU)
Title: Process for producing pharmaceutical compositions containing antibody-enzyme conjugates and medicament-precursors for transporting citostatics into the tumor celles, and process for producing medicament-precursors
Inventor: SENTER PETER DANA
IPC: A61P35/00
Filed: 1988-08-03
Abstract: This invention relates to anthracycline prodrugs allowing the delivery of cytotoxic drugs to tumor cells by the administration of a tumor-specific antibody-enzyme conjugate that binds to the tumor cells, and the additional administration of the prodrug that is converted at the tumor site, in the presence of the antibody-bound enzyme, to an active cytotoxic drug. The present invention also relates to a method for preparing these prodrugs. According to one embodiment of the invention, an antibody-enzyme conjugate containing the enzyme, penicillin V amidase ("PVA"), has been used in conjunction with a novel prodrug, N-(p-hydroxyphenoxyacetyl)adriamycin to effect killing of tumor cells. The products of this invention provide for enhanced selective killing of tumor cells and are thus useful in the treatment of cancers and other tumors.
Patent HU-187937-B (HU)
Inventor: LENK NORBERT
IPC: G01N15/12
Filed: 1983-12-01
Abstract: Gegenstand der Erfindung ist eine Messduese zur Erfassung der in einem Elektrolyten suspendierten Teilchen. Hauptziel ist es, die Fehlerquote bei der Erfassung von Teilchen unterschiedlicher Groessenordnung zu senken. Der Erfindung lag die Aufgabe zugrunde, eine Messduese mit homogener Feldzone im Austrittsbereich der Teilchen zu schaffen. Erfindungsgemaess geschieht dies dadurch, dass mindestens eine der beiden Stirnseiten der Messduese, vorzugsweise die im Austrittsbereich der Teilchen gelegene, mit einer leitfaehigen Schicht versehen ist.
Patent HU-187207-B (HU)
Inventor: BARTOK SANDOR P
IPC: G06F9/28
Filed: 1982-12-30
Abstract: tot, végül a vezérlőjeleket, amely vezérlőjelekre válaszjelet
nem küld az operatív memória. A cím kiadása után megvizsgájuk, hogy a kiadott cím megtalálható-e a
gyors memóriában, azaz címtalálat jön létre, és ameny- nyiben igen, abban az esetben azonnal válaszjelet generálunk,
ellenkező esetben kiadjuk a vezérlőjeleket a
buszra az operatív memória felé. A berendezésnek központi egysége, gyors és operatív memóriája és perifériás egységei vannak. A vezérelt
gyors memória ki/bemenetei részben központi vezetékkötésen
keresztül a központi egységre, részben a buszra vannak kötve.
Patent HU-199564-B (HU)
Title: Charging apparatus for blast furnaces
Inventor: TARASOV VLADIMIR P
IPC: C21B7/18
Filed: 1986-07-30
Abstract: A charging device for a blast furnace in which the outlet openings of bowls (4, 8) consecutively located along the mix path are covered by shutters (6, 9) provided with a conical side surface and mounted with the possibility of reciprocating movements. The shutter (9) covering the lower bowl (8) is shaped as a truncated hollow cone in the upper part of which is mounted a hopper (10) oriented by its narrowing part towards the cavity of the truncated cone. The hopper is provided with profiled openings, spread over the entire surface of its walls, and with a screen (11) shaped as a hollow truncated cone adjoining by its smaller base the lower edge of the hopper.
Patent HU-208228-B (HU)
Title: Insecticidal and acaricidal compositions comprising azole derivatives as active ingredient and process for producing antihelmetic pharmaceutical compositions and the active ingredients
Inventor: WILLIS ROBERT JOHN
IPC: A01N43/647
Filed: 1990-08-09
Abstract: Compounds of formula I
       
 and salts thereof, 
in which 
Ar is aryl; 
W is N and Z is CR⁵; or W is CR¹ and Z is N or CR⁵; 
A is S(O) m , -CH=CH-, O or NH; 
R¹ is hydrogen, optionally substituted alkyl, halogen or R²⁰S(O) q ; 
R² and R³ are hydrogen, alkyl, alkenyl or alkynyl, each of which is optionally substituted, aryl, heterocyclyl, cyano, halogen, nitro, YR²⁰, S(O)₂NR⁸R⁹, CHO and functional derivatives thereof, NR⁸R⁹ or CYNR⁸R⁹; 
either (i) R⁴ and R⁷ which may be the same or different, are hydrogen, optionally substituted alkyl, optionally substituted alkenyl, acyl or optionally substituted alkoxycarbonyl, and R⁶ is hydrogen, or 
(ii) R⁴ is as defined above and R⁶ and R⁷ form a bond or R⁷ is as defined above and R⁴ and R⁶ form a bond; 
R⁵ is hydrogen, alkyl, optionally substituted amino or halogen; 
R⁸ and R⁹ are the same or different and are hydrogen, optionally substituted alkyl, acyl or aryl, or together with the nitrogen to which they are attached, form a 5 to 7 membered ring which can contain other hetero atoms; 
R²⁰ is optionally substituted alkyl; 
Y is O or S; 
m is 0, 1 or 2; 
p is 0 or 1; 
n is 0, 1 or 2; and 
q is 0, 1 or 2, with the proviso that when W is CR¹ and Z is CR⁵ and n and p are both O, R⁴ and R⁷ are not alkyl, 
have pesticidal activity especially against insects, acarids and animal endoparasites.
Patent HU-215883-B (HU)
Inventor: BELIJJ JURIJJ PETROVICH
IPC: B01D46/00
Filed: 1990-12-10
Abstract: A találmány tárgya nagy szennyelnyelő képességű szűrő (1), előnyösenőlaj, víz, illetve egyéb főlyadékők és levegő, illetve gázőkszűrésére, amelynek főrmája lap, tárcsa, hengeres vagy kúpős alakú. Anagy szennyelnyelő képességű szűrőre (1) jellemző, hőgy egyetlenanyagból van, amely pőrózűs szerkezetű, kőnkáv üregekből (2)fémkőhászati öntéssel, kőmpőzíciós eljárással kerül előállításra ŕ
Patent IT-1180634-B (IT)
Inventor: BERETTA PIER GIUSEPPE
IPC: F41A19/00
Filed: 1984-12-10
Granted: 1987-09-23
Abstract: A tripping mechanism (3) is disclosed for the conversion of automatic rifles of the so-called closed-bolt to rifles of the open-bolt type. The components of the mechanism are premounted within a box-like support (2) which is readily insertable in the trip box (1) of a conventional automatic rifle. The mechanism includes a trigger (7), a trip block (8) for arresting the bolt carriage (4) in the open, armed position, a connecting rod (9) attached to and displaceable with the trigger (7) and cooperating with the trip block (8) during the disengagement of the bolt carriage from its blocked position, a safety rod (6) operating also as selector of the firing mode by cooperating with a lever, a lever (11) for engaging the trigger during the automatic, continuous firing mode, and, finally, a safety block (10) for arresting the bolt carriage (<sub>4</sub>) in the event of accidental disengagement from the trip block (8).
Patent IT-1233722-B (IT)
Title: stanchion to realise shelves and similar products
Inventor: MAURO LATINI
IPC: F16B/
Filed: 1989-07-28
Granted: 1992-04-14
Abstract: Stanchion (1) has a cylindrical shape and is provided with at least one annular vent (7) hosting elastic annular element (9). Once installed, said annular element leans from said annular vent, so as to cooperate with the internal surface (11) of a flange (7) set on said stanchion, wherein transversals are bound to said flange, so as to form a joint structure.
Patent LV-13898-B (LV)
Title: Heating device for piglets
Inventor: ZIEMELIS IMANTS
IPC: F24D3/00
Filed: 2009-02-04
Abstract: The present invention relates to the heating devices of piglets with heated floors (more specifically, with heated floor panels) and the infrared radiation lamps used for heating piglet dens in the piggeries. The device consists of: a panel, for instance, of a sectoral shape, heated by means of water, in which a heating element formed of pipes is mounted; two angularly connected panels one of which having an inwardly directed edge with a pivotally openable cover attached to it. In order to improve the technical-economical characteristics, its inner sides are covered with a heat reflecting film over which the heat exchanger (radiator) coil is fixed at a certain distance consisting of flexible pipes connected through the water valve to the heating element of the panel and/or the hot water main pipeline.
Patent LV-14801-B (LV)
Title: Reluctance synchronous motor
Inventor: BRAKANSKIS ULDIS
IPC: H02K19/02
Filed: 2013-12-04
Abstract: Synchronous reluctance motor with high specific electromagnetic torque is proposed. Motor contains a teethed outer rotor (1) without windings and inner stator (2), where into the six large slots three-phase armature winding is placed (3) (Fig.1). The rotor teeth (4) have two units higher than the number of stator teeth (5). Number of stator teeth between the major slots, such as (6) and (7) in which the armature winding (3) is placed, is greater than one. Stator and rotor teeth are spaced evenly, regardless of the armature winding (3) in the presence of the stator. The rotating magnetic field appears by connecting three-phase armature winding to the alternating current source. The magnetization force caused by armature winding exerts an effect on rotor that is trying to take a position by magnetization force to the peak area of the rotor teeth facing towards the stator teeth. Turning the rotating magnetic field by 90 grades iniciates the shift of rotor's teeth position by half of teeth section. The rotor starts to rotate, but at a reduced rotational velocity relative to the rotating magnetic field. The electromagnetic torque can be defined as the partial derivative of the magnetic field energy stored in air gap at the rotor with respect to turning angle. The torque increases by increasing the stator and rotor teeth number to a certain extent.
Patent LV-11321-B (LV)
Title: Isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyano-phenyl)-1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylate
Inventor: HEINRICH MEIER
IPC: C07D211/90
Filed: 1994-12-09
Abstract: The present invention relates to the compound rac-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarb oxylate and its pure enantiomers, to processes for the preparation thereof and to the use thereof as pharmaceutical, in particular for treatment of cerebral and neuronal disorders and to an intermediate for the preparation thereof.
Patent ME-00111-B (ME)
Title: Use of tricyclic compounds as glycine transport inhibitors
Inventor: DARGAZANLI GIHAD
IPC: C07D487/08
Filed: 2004-10-15
Abstract: N-heterocyclylmethyl benzamide derivatives (I) and their acid addition salts, solvates and hydrates are new. N-heterocyclylmethyl benzamide derivatives of formula (I) and their acid addition salts, solvates and hydrates are new. [Image] R : H or vinyl; n : 0 or 1; X : CH or N; R 1 : phenyl or naphthyl optionally substituted by halo, 1-6C alkyl, 1-6C alkoxy or CF 3; or thienyl, pyridyl, oxazolyl, furyl, thiazolyl, quinolinyl or isoquinolinyl; R 2 : H, halo, CF 3, A, OA, thienyl, OAr, SH, SA, SO 2NR 4R 5, SO 2A, SO 2Ar, CN, CONR 4R 5, COOR 7, COA, COAr, NHCOR 8, NHSO 2A, NHSO 2Ar or NHSO 2NR 4R 5; A : 1-6C alkyl optionally substituted by R 3; Ar : phenyl optionally substituted by R 6; R 3 : halo, phenyl, 1-6C alkoxy or NR 4R 5; R 4, R 5 : H or 1-6C alkyl; or NR 4R 5 : pyrrolidino, piperidino or morpholino; R 6 : H, OH, SH, 1-6C alkyl or 1-6C alkoxy; R 7 : H, A or Ar; R 8 : A, 1-6C alkoxy or Ar; and provided that when R is vinyl, then n is 1 and X is CH. ACTIVITY : Nootropic; Neuroleptic; Tranquilizer; Antidepressant; Antialcoholic; Antimigraine; Relaxant; Analgesic; Antiparkinsonian; Anticonvulsant; Neuroprotective. MECHANISM OF ACTION : Glycine transporter inhibitor. The most active compounds (unspecified) have IC50 values of 0.01-10 MicroM against glycine uptake by SK-N-MC cells expressing native human glycine transporter glyt1.
Patent MX-167166-B (MX)
Title: Inhibidores de corrosion
Inventor: MARTINEZ ROBERT G
IPC: C10N60/00
Filed: 1986-01-14
Abstract: La presente invención se refiere a un inhibidor de corrosión preparado por tratamiento térmico del producto de reacción de: A) aldehido alfa, beta-etilénicamente insaturado, y B) una poliamina orgánica; a una temperatura de por lo menos 170 grados C y por un tiempo de alrededor de 10 minutos a 48 horas, los cuales son suficientes para proveer un incremento en la estabilidad térmica de al menos unos 25 grados C en comparación con la estabilidad térmica del producto de reacción antes del tratamiento térmico.
Patent MX-166712-B (MX)
Title: Composiciones polimerizables
Inventor: ORTON MICHAEL LESLYE
IPC: C08L75/04
Filed: 1986-01-24
Abstract: La presente invención se refiere a una composición polimerizable que comprende un uretano insaturado que es un poliacrilato ó polimetacrilato de poliuretano, resina, derivada de un acrilato o metacrilato de hidroxialquilo mediante la reacción de los grupos hidroxilo del mismo, con los grupos isocianato de: i) un poliisocianato libre de grupos de uretano y que tiene un número promedio de funcionalidad de isocianato de cuando menos 2.0 ó ii) un poliisocianato de uretano derivado de un poliisocianato mediante la reacción del mismo con los grupos hidroxilo de un compuesto polihidroxi, poliisocianato de uretano citado que tiene un número promedio de funcionalidad de isocianato de cuando menos 2.0; b) un monómero de metacrilato adecuado de la fórmula general: en donde R es un grupo hidrocarbilo que contiene uno ó dos átomos de carbono; y c) cuando menos una substancia polimerizable de adición, etilénicamente insaturada, que i) contiene cuando menos un grupo etilénicamente insaturado, ii) es copolimerizable con la mezcla de uretano insaturado y el monómero de metacrilato adecuado, y tiene una reactividad de polimerización, tanto con la mezcla antes mencionada como en sí mismo, de tal manera que la concentración del monómero de metacrilato adecuado al desmoldear el producto preparado tras la polimerización de una composición polimerizable de acuerdo con la presente invención, es inferior a la concentración del monómero de metacrilato adecuado que se podría obtener en el producto que se obtendría tras la polimerización de la composición polimerizable en ausencia de cuando menos una substancia polimerizable de adición, etilénicament e insaturada, de la composición polimerizable.
Patent NO-137691-B (NO)
Title: Analogifremgangsm}te for fremstilling av nye terapeutisk aktive pyrimidinderivater
Inventor: CARRAZ GILBERT
IPC: C07B61/00
Filed: 1973-07-20
Abstract: Analogifremgangsmåte for fremstilling av nye terapeutisk aktive pyrimidinderivater.
Patent NO-158421-B (NO)
Inventor: STRUPCZEWSKI JOSEPH T
IPC: C07D417/04
Filed: 1985-04-22
Abstract: There are described novel anthypertensive 1,2-benzisothiazole piperidines of the formulawhere X is hydrogen, halogen, loweralkoxy, loweralkyl, nitro, amino or trifluoromethyl; and R isR, being loweralkyl, aryl, aralkyl, cycloalkylloweralkyl or a a loweralkyl substituted with an amino, loweralkylamino or diloweralkylamino, and R<sub>2</sub> being hydrogen, loweralkyl or aryl; antihypertensive compositions comprising said compounds or pharmaceutically acceptable acid addition salts thereof; and methods for synthesizing the same.
Patent NO-167104-B (NO)
Inventor: BAKER GERALD S
IPC: F16K1/48
Filed: 1987-10-01
Abstract: A choke includes a body (12) with an internal valve chamber (18), an inlet (14) and an outlet (16) communicating through the body into the valve chamber. A valve seat (20) surrounds the opening of the outlet into the valve chamber, and a valve member (30) is mounted within said body to move toward and away from said valve seat to control flow therethrough. Means are provided for moving the valve member in the body. The valve member (30) has a stem (32) and a replaceable, wear-resistant tip (42) which is provided with a sleeve insert (48) secured within the stem opening and has internal threads which mate with external threads on the end of the stem. The tip recess includes a groove (62) into which a portion of the sleeve insert is swaged to secure it tightly into the tip.
Patent NO-180196-B (NO)
Inventor: FLYNN GARY ALAN
IPC: C07K5/06
Filed: 1991-12-20
Abstract: The present invention relates to compounds of the formula <CHEM>  wherein A is methylene, oxygen, sulfur or N-B wherein B is R1 or COR2 wherein R1 is hydrogen, a C1-C4 alkyl or an Ar-Z-group wherein Ar is aryl and Z is a C0-C4 alkyl and R2 is a -CF3, a C1-C10 alkyl or an Ar-Z group;     R is hydrogen or a C1-C4 alkyl; and X and Y are each independently hydrogen, nitro or amino, with the proviso that when X is nitro or amino, Y must be hydrogen, and when Y is nitro or amino, X must be hydrogen; and  pharmaceutically acceptable salts thereof, which are inhibitors of Angiotensin Converting Enzyme.
Patent ZA-802443-B (ZA)
Title: Chromophoric cephalosporins and process for their manufacture
Inventor: SCHINDLER P
IPC: C07D501/42
Filed: 1980-04-23
Abstract: A chromophoric cephalosporin composition having the formula   <IMAGE> is utilized for the detection of  beta -lactamases. Detection of beta -lactomases can be carried out by diluting the compound in solution or by a test strip carrier.
Patent ZA-811053-B (ZA)
Title: Detector for detecting air components
Inventor: KLAIJ H
IPC: G01N31/22
Filed: 1981-02-17
Abstract: The invention provides a detector for detecting air components, e.g. contaminations, and in particular noxious or poisonous contaminations, which device comprises a housing in which an air pervious carrier containing a first reagent is arranged, this detector being adapted to draw air to be tested through said carrier so as to expose this reagent to the air, this reagent being influenced by the components to be detected, which carrier is to be contacted with a second reagent which, together with the first one, can bring about a colour reaction depending on the fact whether the first reagent has been influenced or not. The housing forms, in the operative condition, an integral unit, an air- and liquid-tight container with a rupturable wall and containing a not contaminated liquid contributing to said colour reaction being arranged within said housing, the latter being, furthermore, provided with a yieldable wall portion and a plurality of piercing pins arranged in such a mutual spatial relationship that the container can be pierced by pressing inwards said wall portion, so as to moisten said reagent carrier with the liquid from said container. In particular the second reagent can be contained in a similar second carrier which is normally separated from the first one but is contacted therewith when pressing inwards said wall portion.
Patent ZA-818728-B (ZA)
Title: Radiation polymerziable mixture and radiation senstive recording material produced therefrom
Inventor: GEISSLER ULRICH
IPC: C08F2/00
Filed: 1981-12-17
Abstract: A radiation-polymerizable mixture comprising a polymeric binder, a radiation-activatable polymerization initiator and a polymerizable acrylate or methacrylate ester having at least two urethane groups in the molecule, said ester being a reaction product of glycerol dimethacrylate or glycerol diacrylate and a polyisocyanate obtained by reacting a polyhydroxy compound having from two to six hydroxyl groups with a diisocyanate or a reaction product of glycerol dimethacrylate or glycerol diacrylate and a diisocyanate. The new polymerizable urethanes provide the mixture with a high light-sensitivity, good reciprocity and a low tendency to crystallize.
Patent ZA-825703-B (ZA)
Title: Film support element assembly
Inventor: SHAW WILLIAM CHESTER
IPC: G03B41/02
Filed: 1982-08-06
Abstract: A film support element assembly (20) is disclosed, primarily for supporting film (42) in relation to a projection aperture in a motion picture projector having a rolling loop film transport mechanism. In a preferred embodiment the film support element (44; 44') is a so-called «field flattener» and has a cylindrically curved surface over which successive frames in the film are laid by the mechanism. Cleaning means (52, 54; 154, 156; 186, 188; 220, 222; 234; 234<sub>'</sub>) are provided adjacent the film path and the lens element can be displaced to bring a fresh portion of the surface into the film path. At the same time, the cleaning means remove debris from the surface. In one embodiment the lens element (44<sub>'</sub>) is vibrated (234; 234') to discourage adhesion of debris.
Patent ZA-838426-B (ZA)
Title: Piezoelectric fluid control device
Inventor: SIEGAL BURTON L
IPC: F16K31/00
Filed: 1983-11-11
Abstract: A fluid control device includes a piezoelectric bender (48a, 48b) co-operating with an impacting member (30) to deform a membrane (24) over a valve seat (29) upon energisation or de-energisation for achieving desired rapid and accurate contrrol to fluids under pressure in a variety of different applications, such as, computer printing, fluidics, etc. The bender (48a 48b) as well as the impacting member (30) are each advantageously isolated from the fluid.
Patent ZA-841351-B (ZA)
Title: Baler
Inventor: LIET CORNELIS HENDRICUS
IPC: A01F15/07
Filed: 1984-02-23
Abstract: The invention relates to a device for forming a compressed produce bale, which is provided with a compacting cage, supported on an undercarriage, with an inlet for the produce and a pick-up for collecting the produce. The compacting cage has a polygonal, preferably square or rectangular cross section, and is bounded by at least approximately planar, stiff side walls, the inlet and the compacting cage being adjustable relative to each other in such a manner, that uniform filling of the whole cross sectional shape of the compacting cage is achieved.
Patent ZA-868592-B (ZA)
Title: Use of alkoxyhydroxy fatty acids as corrosion inhibitors in oils and oil-containing emulsions
Inventor: BORGGREFE GERHARD
IPC: C10M129/44
Filed: 1986-11-12
Abstract: Acid cleaning/pickling compositions for metal surfaces containing (A) at least one protein-derived polymer, sugar-derived polymer, sorbitol, tannin, or vinyl-based polymer, (B) at least one iodine or iodine-affording compound; acids solutions prepared therefrom; and methods for their use.
Patent ZA-875068-B (ZA)
Title: Method of folding into packages disposable absorbent articles,e.g.diapers,in connection with the production thereof
IPC: A61F13/15
Filed: 1987-07-10
Abstract: The present invention relates to a method of folding into packages, during manufacture thereof, disposable absorbent articles such as diapers, incontinence protectors or the like provided with elastic threads (6,7). The distinguishing feature of the invention is that the article ends are folded in with approximately equal lengths over the central area of the article in question which is then folded together in the same direction into a four-folded state, the elastic portions (6',7') located in the center of the article simultaneoulsy being laterally stretched so that the article ends are laterally positioned inside said elastic portions, the folded article upon release of said elastic portions being held compressed thereby in the state of a compact, four-folded package.
Patent ZA-878870-B (ZA)
Title: Device for removing a staple from a stapled bundle of sheets
IPC: B25C11/00
Filed: 1987-11-26
Abstract: Device for removing a staple (34) from a stapled bundle of sheets (35) by moving the bundle (35) over a supporting element (10) past a staple removing strip (25). The strip (25) extends above the supporting element (10) at a small acute angle therewith and is fixed to an arm (18) which is rotatably mounted on a shaft (17) positioned at the side of the strip (25) facing away from the acute angle and below the supporting element (10). The strip (25) is moved upwards when a stapled bundle of sheets (35), with the legs of the staple (34) facing downwards, is fed between the supporting element (10) and a wedge-like tapering end (27) of the strip (25), which end (27) presses onto the supporting element (10). When in this way the staple (34) is positioned in front of the wedge-like tapering end (27) of the strip (25), the bundle (35) is pulled towards the strip (25), the end (27) of the strip (25) penetrating between the crown of the staple (34) and the bundle (35) and the staple (34) thereafter being pulled out of the bundle (35). The pulled-out staple (34) drops in a receiving tray (6) formed beneath the supporting element (10).