Patent SG-11201900845Y-A (SG)
Title: Uses of il-13 antagonists for treating atopic dermatitis
Inventor: LIN CHINYU
IPC: A61K39/02
Filed: 2017-09-22
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 29 March 2018 (29.03.2018) WIPO I PCT omit °nolo olmoom 111°11E1E1m oimIE (10) International Publication Number WO 2018/057849 Al (51) International Patent Classification: A61K 39/02 (2006.01) (21) International Application Number: PCT/US2017/052891 (22) International Filing Date: 22 September 2017 (22.09.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/398,713 23 September 2016 (23.09.2016) US 62/527,204 30 June 2017 (30.06.2017) US 62/530,683 10 July 2017 (10.07.2017) US 62/539,037 31 July 2017 (31.07.2017) US (71) Applicant (for all designated States except AL, AT, BA, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR): GENENTECH, INC. [US/US]; 1 DNA Way, South San Francisco, Califor- nia 94080 (US). (71) Applicant (for AL, AT, BA, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR only): F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, 4070 Basel (CH). (72) Inventors: LIN, ChinYu; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). OMACHI, Theodore A.; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). OWEN, Ryan P.; c/o Genentech, Inc., 1 DNA Way, South San Francis- co, California 94080 (US). YEN, Karl; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). ZHENG, Yanan; 21870 Lomita Avenue, Cupertino, Cal- ifornia 95014 (US). DEBUSK, Kendra; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). - (74) Agent: DAVIS, Jennifer L. et al.; c/o Genentech, Inc., 1 DNA Way, Mail Stop 49, South San Francisco, California 94080 (US). — (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(ii)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) of inventorship (Rule 4.17(iv)) Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) 00 N O CO (54) Title: USES OF IL-13 ANTAGONISTS FOR TREATING ATOPIC DERMATITIS 0 (57) : Uses of IL-13 antagonists for treating atopic dermatitis are provided. Also provided are methods of treating atopic \" dermatitis and methods of reducing the severity of atopic dermatitis by administering IL-13 antagonists.