baber/WOPTO huggingface dataset:
Patent BR-112022015363-A2 (BR)
Title: Uso de um antagonista do receptor de interleucina-4 (il-4r), composição farmacêutica e recipiente para tratar dermatite atópica (da) ou melhorar um parâmetro associado à da em um indivíduo
Inventor: ASHISH BANSAL
IPC: A61P17/00
Filed: 2021-03-26
Abstract: USO DE UM ANTAGONISTA DO RECEPTOR DE INTERLEUCINA-4 (IL-4R), COMPOSIÇÃO FARMACÊUTICA E RECIPIENTE PARA TRATAR DERMATITE ATÓPICA (DA) OU MELHORAR UM PARÂMETRO ASSOCIADO À DA EM UM INDIVÍ- DUO. A presente invenção refere-se a métodos para tratar dermatite atópica moderada à grave em um indivíduo pediátrico. Em um aspecto, os métodos compreendem administrar ao indivíduo uma ou mais doses de um antagonista do receptor de interleucina-4 (IL-4R), tal como um anticorpo anti-IL-4R ou fragmento de ligação ao antígeno do mesmo.
Patent BR-112022016417-A2 (BR)
Title: Sistema, dispositivo e método para imageamento ocular conectado e inteligente
Inventor: JOSE AUGUSTO STUCHI
IPC: A61B3/00
Filed: 2020-08-19
Abstract: SISTEMA, DISPOSITIVO E MÉTODO PARA IMAGEAMENTO OCULAR CONECTADO E INTELIGENTE. A presente invenção consiste em um sistema, dispositivo e método para imageamento portátil sendo composto por módulos ópticos, eletrônicos e mecânicos, de ergonomia e design funcional específicos, configurados para obter imagens e vídeos no espectro visível e infravermelho dos segmentos anterior e posterior do olho humano, principalmente exames de retina não-midriáticos controlados por dispositivo móvel externo, como smartphones, tablets ou hardware embarcado, para propósitos clínicos.
Patent BR-112022022789-A2 (BR)
Title: Método de triagem para uma planta de estévia com alto teor de glicosídeo de esteviol, kit de triagem, planta de estévia com alto teor de glicosídeo de esteviol, semente, tecido, folha seca, cultura de tecido ou célula, métodos para produzir uma planta de estévia com alto teor de glicosídeo de esteviol, um extrato, glicosídeo de esteviol e um alimento ou bebida, uma composição adoçante, um sabor ou um medicamento, e, extrato da planta ou da semente, do tecido, da folha seca, da cultura de tecido ou da célula
Inventor: TADAYOSHI HIRAI
IPC: A61K47/26
Filed: 2021-05-11
Abstract: MÉTODO DE TRIAGEM PARA UMA PLANTA DE ESTÉVIA COM ALTO TEOR DE GLICOSÍDEO DE ESTEVIOL, KIT DE TRIAGEM, PLANTA DE ESTÉVIA COM ALTO TEOR DE GLICOSÍDEO DE ESTEVIOL, SEMENTE, TECIDO, FOLHA SECA, CULTURA DE TECIDO OU CÉLULA, MÉTODOS PARA PRODUZIR UMA PLANTA DE ESTÉVIA COM ALTO TEOR DE GLICOSÍDEO DE ESTEVIOL, UM EXTRATO, GLICOSÍDEO DE ESTEVIOL E UM ALIMENTO OU BEBIDA, UMA COMPOSIÇÃO ADOÇANTE, UM SABOR OU UM MEDICAMENTO, E, EXTRATO DA PLANTA OU DA SEMENTE, DO TECIDO, DA FOLHA SECA, DA CULTURA DE TECIDO OU DA CÉLULA. A presente invenção provê: uma planta de estévia contendo alto teor de glicosídeo de esteviol tendo as características genéticas (1) e (2) abaixo; um método de produção para a dita planta; e um método de triagem. (1) Alelos, em que a base na posição correspondendo à posição 290 de SEQ ID:1 é T, são homozigotos. (2) Alelos, em que a base na posição correspondendo à posição 40 de SEQ ID:2 é A, são homozigotos ou heterozigotos.
Patent BR-112022023744-A2 (BR)
Title: Métodos para produzir um catalisador pós-metalocênico atenuado, de alimentar um catalisador pós-metalocênico a um reator de polimerização em fase de lama ou em fase gasosa e para produzir um polímero poliolefínico, catalisador pós-metalocênico atenuado, e, sistema de catalisador multimodal
Inventor: BETHANY M NEILSON
IPC: C08F110/14
Filed: 2021-05-26
Abstract: MÉTODOS PARA PRODUZIR UM CATALISADOR PÓSMETALOCÊNICO ATENUADO, DE ALIMENTAR UM CATALISADOR PÓS-METALOCÊNICO A UM REATOR DE POLIMERIZAÇÃO EM FASE DE LAMA OU EM FASE GASOSA E PARA PRODUZIR UM POLÍMERO POLIOLEFÍNICO, CATALISADOR PÓS-METALOCÊNICO ATENUADO, E, SISTEMA DE CATALISADOR MULTIMODAL. A presente invenção se refere a um método para produzir um catalisador pós-metalocênico de light-off atenuado ("catalisador pós-metalocênico atenuado" ou "catalisador P-M atenuado), sendo que o método compreende combinar um catalisador de light-off mais rápido com uma quantidade eficaz de um composto modificador de cinética de fórmula (A1), (B1) ou (C1): R5-C=C-R6 (A1), (R5)2C=C=C(R6)2 (B1), ou (R5)(R7)C=C(R6)(R7) (C1), conforme definido aqui, sob condições de reação eficazes para obter um catalisador pós-metalocênico atenuado que exiba um perfil de cinética de light-off atenuado (em relação àquele do catalisador de light-off mais rápido); sendo que o catalisador de light-off mais rápido foi produzido mediante a ativação de um pré-catalisador pós-metalocênico (isto é, uma "entidade de coordenação" ou "complexo de ligante-metal" não ativado) de fórmula estrutural (I): (D)dM(T)t(Q)q(X)x (I) conforme definido aqui; e métodos, composições e usos relacionados.
Patent BR-112022025214-A2 (BR)
Title: Procedimento para obtenção de gadoterato de meglumina a partir de tetraxetano de alta pureza (dota) e sua utilização na preparação de formulações galênicas injetáveis
Inventor: IGNACIO ALONSO SILVA
IPC: C07D257/02
Filed: 2021-06-10
Abstract: PROCEDIMENTO PARA OBTENÇÃO DE GADOTERATO DE MEGLUMINA A PARTIR DE TETRAXETANO DE ALTA PUREZA (DOTA) E SUA UTILIZAÇÃO NA PREPARAÇÃO DE FORMULAÇÕES GALÊNICAS INJETÁVEIS. A presente invenção refere-se a um processo para obter gadoterato de meglumina a partir de tetraxetano de alta pureza (DOTA) que não requer o uso de solventes orgânicos e otimiza as condições do processo sintético. O tetraxetano a partir do qual o gadoterato de meglumina é obtido por um processo sintético que inclui uma etapa de purificação na qual pelo menos uma eletrodiálise é realizada. Este procedimento torna possível obter um tetraxetano e um gadoterato de meglumina com quantidades mínimas de impurezas.
Patent BR-112023003553-A2 (BR)
Title: Assinatura de localização celular e imunoterapia
Inventor: GEORGE C LEE
IPC: C07K16/28
Filed: 2021-08-31
Abstract: ASSINATURA DE LOCALIZAÇÃO CELULAR E IMUNOTERAPIA. A presente invenção refere-se a métodos para identificar um indivíduo adequado para uma terapia com antagonista anti-PD-1/PD-L1 compreendendo medir a localização de CD8 do ensaio e a expressão de PD-L1 em uma amostra de tumor obtida do indivíduo. Em alguns aspectos, o método ainda compreende a administração de (i) uma terapia com antagonista anti-PD-1/PD-L1 ou (ii) uma terapia combinada com antagonista anti-PD-1/PD-L1 e antagonista anti-CTLA-4 a um indivíduo identificado de ter um tumor que apresenta um fenótipo de localização de CD8 excluído, em que o tumor é PD-L1 negativa.
Patent BR-112023003786-A2 (BR)
Title: Medição de símbolo seletivo para posicionamento
Inventor: ALEXANDROS MANOLAKOS
IPC: H04L5/00
Filed: 2021-09-08
Abstract: MEDIÇÃO DE SÍMBOLO SELETIVO PARA POSICIONAMENTO. Um método para medir um PRS OFDM sem fio em um equipamento de usuário inclui: selecionar um subconjunto de símbolos de um grupo de símbolos do PRS OFDM, o PRS OFDM compreendendo uma partição de símbolos compreenden-do o grupo de símbolos, o grupo de símbolos consistindo em uma primeira quantidade de símbolos de consecutivos dos símbolos, o grupo de símbolos sendo totalmente esca-lonado no domínio da frequência, o subconjunto de símbo-los consistindo em uma segunda quantidade de símbolos dos símbolos do grupo de símbolos, a segunda quantidade de símbolos sendo menor que a primeira quantidade de símbolos e o subconjunto de símbolos sendo menos do que totalmente escalonado no domínio da frequência; e medir o subconjunto de símbolos sem medir todos os símbolos do grupo de símbolos.
Patent BR-112023007922-A2 (BR)
Title: Método de geração de linfócitos infiltrantes no tumor, método para expandir uma população de linfócitos infiltrantes no tumor (tils) ou linfócitos infiltrantes na medula (mils) e métodos de tratamento de câncer em um sujeito
Inventor: BEG AMER
IPC: C12N15/86
Filed: 2021-10-27
Abstract: método de geração de linfócitos infiltrantes no tumor, método para expandir uma população de linfócitos infiltrantes no tumor (tils) ou linfócitos infiltrantes na medula (mils) e métodos de tratamento de câncer em um sujeito. são divulgados métodos para expandir populações de linfócitos infiltrantes de tumor (til) e métodos de uso da população de til expandida para tratamento de câncer.
Patent SK-593-A3 (SK)
Title: Insekticide agent
Inventor: FRAJSTAK PAVOL
IPC: A01N57/10
Filed: 1993-01-07
Abstract: Agent contains 10 to 100 g/l of 0,0-diethyl-0(2-quinoxalyl) thiophosphate, 500 to 900 g/l of methylesters of high greasy acids contained in vegetable oils, 100 to 230 g/l at least one nonionogenic emulgator or casually 10 to 200 g/l unpolar solvent.
Patent CZ-7996-A3 (CZ)
Title: Vehicle heating with two circuits
Inventor: HUMBURG MICHAEL
IPC: B60H1/03
Filed: 1994-06-23
Abstract: The description relates to a vehicle heater with two circuits. On circuit leads from the vehicle's engine (1) via a heating device (3) and a heat exchanger (5) back to the engine (1), while the other circuit leads from the heating device (3) via the heat exchanger (5) back to the heating device (3). These two circuits may be automatically switched by a single valve, a two-way valve (8) structurally combined with a check valve (9), so that no auxiliary power, e.g. current from the vehicle battery, is needed.
Patent SK-3495-A3 (SK)
Title: Method of arrangment of tourney and device for realization of this method
Inventor: EIBA PETER
IPC: G07F17/32
Filed: 1993-07-09
Abstract: PCT No. PCT/EP93/01001 Sec. 371 Date Jan. 11, 1995 Sec. 102(e) Date Jan. 11, 1995 PCT Filed Jul. 9, 1993 PCT Pub. No. WO94/01839 PCT Pub. Date Jan. 20, 1994A system for automated running of sports contests including a computer unit, a machine-readable data carrier for each such contestant, a data carrier containing control data for each type of contest to be performed, and at least one reader for the data carrier. Contestant data and control data are exclusively input into the computer unit using the data carriers. At least one display device linked to the computer unit displays contest data. The individual phases of the contest running may be determined by the sequence of the data carriers introduced in the reader(s).
Patent CZ-21794-A3 (CZ)
Title: Method of launching a projectile being not guided in vertical direction from a mobile transport means and a device for its delayed motion along a determined trajectory
Inventor: DUCLOS FRANCOIS
IPC: F42B25/00
Filed: 1994-02-01
Abstract: Method of launching a projectile (2) which is not guided vertically, with a trajectory (5) which is compound, free, of adjustable duration, then retarded, against a target (4) from a moving vehicle (1) in which method, before launch, and for various positions of the vehicle (1),     the target (4) is identified, the distance from the target (4) to an anticipated virtual trajectory at maximum range (6) of the projectile (2) is calculated and the projectile (2) is launched after the said distance has crossed a minimum, and then, in the calculation, the maximum-range trajectory (6) is replaced by a compound trajectory (25), in which the transit time (TB1) of the free trajectory (26) is controlled in such a way that the distance from the target (4) to the trajectory of the projectile (25) remains equal to this minimum and the projectile (2) is sent a free-trajectory transit time signal (26). <IMAGE>
Patent CZ-61099-A3 (CZ)
Title: Screwing tap for cold forming with inner finishing cutting edge and process for producing thereof
Inventor: SUGANO HIROTO
IPC: B23G7/02
Filed: 1997-07-16
Abstract: The cold forming tap according to the present embodiment is constructed such that ones of protruding portions which are located adjacent to each other in the axial direction are removed down to a root of a thread of the cold forming tap, and a portion corresponding to the root of each of the removed protruding portions is provided with the cutting edge having a diameter equal to a minor diameter of an internal thread to be formed by the cold forming tap. This construction permits a maximum diameter position of the root not to be located at relief portions which are adjacent to the protruding portions of the external thread portion, whereby a concave-convex shape defined by the crest and a concave-convex shape defined by the root coincide with each other as viewed in the circumferential direction. This coincidence between the respective concave-convex shapes makes it possible to form simultaneously the ridge and root of the external thread portion with high accuracy and efficiency, by employing a grinding wheel having a thread profile formed on its outer circumferential surface in a step referred to as a thread grinding, considerably facilitating a dimension control of the thread of the external thread portion, and leading to a reduced cost for the production. <IMAGE>
Patent SK-45893-A3 (SK)
Inventor: KOZELUHA JAROSLAV
IPC: H01B17/14
Filed: 1993-05-12
Abstract: Podpera na ukotvenie vodiča, najmä na ukotvenie bleskozvodových
vodičov na plochých strechách stavebných
objektov s povlakovými krytinami, je tvorená kompaktným
telesom (1), ktoré má v hornej časti vytvorené
priebežné vertikálne vybranie (2) s plynulým prechodom
do protiľahlých horizontálnych drážok otvorených
v opačnom smere.
Patent SK-48697-A3 (SK)
Title: Cyclic depsipeptide sulfonylation, sulfenylation and phosphorylation process
Inventor: SCHERKENBECK JURGEN
IPC: C07D273/00
Filed: 1995-10-05
Abstract: PCT No. PCT/EP95/03926 Sec. 371 Date Apr. 10, 1997 Sec. 102(e) Date Apr. 10, 1997 PCT Filed Oct. 5, 1995 PCT Pub. No. WO96/11945 PCT Pub. Date Apr. 25, 1996The present invention relates to a process for the aromatic sulfonylation, sulfenylation, thiocyanation and phosphorylation of cyclic depsipeptides having 6 to 24 ring atoms which are synthesized from  alpha -hydroxycarboxylic acids and  alpha -amino acids and contain at least one phenyl radical, characterized in that these cyclic depsipeptides are reacted with sulfonylating, sulfenylating, thiocyanating or phosphorylating agents, optionally in the presence of catalysts, auxiliaries and/or diluents, to novel thus-obtained compounds, and to their use as endoparasiticides.
Patent SK-72296-A3 (SK)
Title: Herbicidal water-soluble solid granular agent
Inventor: SZAMOSI JANOS
IPC: A01N25/08
Filed: 1996-06-05
Abstract: The present invention provides a solid water soluble granular composition which comprises an imidazolinone herbicide alone or in combination with a second herbicide and a base, preferably wherein the base is present at a ratio of about 0.9 to 2.0 molar equivalents of base to molar equivalents of imidazolinone herbicide. Said composition is storage stable and dissolves rapidly and essentially completely in water for even application to target surfaces.
Patent SK-73293-A3 (SK)
Title: Benzimidazoles, process for their preparation and medicaments contained this compounds
Inventor: HAUEL NORBERT
IPC: A61P27/02
Filed: 1993-07-12
Abstract: The invention relates to benzimidazoles of the general formula <IMAGE>  in which R1 to R4 are as defined in Claim 1, and to 1- and 3-isomer mixtures thereof and the salts thereof which have useful properties. The novel compounds are in particular angiotensin antagonists.
Patent SK-81893-A3 (SK)
Inventor: KLINKO JAN
IPC: B63H15/00
Filed: 1993-07-30
Abstract: Zariadenie vhodné na pohon riečnych plavidiel je tvorené
sústavou obsahujúcou vodný motor (2), ktorého rotorje v
kontakte prostredníctvom prevodového mechanizmu (3) a
súvisiaceho príslušenstva ako sú spojovacie, ovládacie a
ďalšie funkčné potrebné prvky, pripadne priamo iba s využitím
spojovacích, ovládacích ďalších funkčne potrebných
prvkov, s pohyblivým pridržiavacim prvkom (S) ukotveným
ku dnu toku, pričom sústava je upravená na uchytenie
ku konštrukcii plavidla.
Patent CH-653840G-A3 (CH)
Title: Process for protecting keratin-containing materials from attack by keratin-eating insects and 5-phenylcarbamoylbarbituric acid compounds
IPC: C07D239/64
Filed: 1979-08-03
Abstract: The materials are treated with compounds of the formula <IMAGE> where X is oxygen or sulphur, R1 and R2 are each alkyl of 1-4 carbon atoms, alkenyl of 3 or 4 carbon atoms, benzyl or optionally substituted phenyl, R3 is halogen, nitro or C(halogen)3, R4 is hydrogen, halogen or C(halogen)3 and R5 is hydrogen, halogen, methyl or methoxy. The compounds of the formula (1) in which at least one of the two substituents R1 and R2 is phenyl or substituted phenyl and X is oxygen are new.
Patent CZ-328288-A3 (CZ)
Title: Method of and apparatus for controlling a machine or a device with a system of operating places
Inventor: ERNI MARKUS
IPC: D01H13/32
Filed: 1988-05-16
Abstract: A machine (100) comprises two rows (106L, 106R) of material- processing stations lying closely next to one another and an EDP system (BP, SP1....SPn, CZ) for monitoring or controlling the stations. The machine is also equipped with a transportable device (110) for operating the stations. The device has a transmitter/receiver unit SEA and each station has a corresponding unit SEB so that information can be directed between the EDP system and the device via the stations. …<IMAGE>…
Patent CS-343590-A3 (CS)
Title: Continuous, horizontally asymmetric, steel railway rail, process forproducing thereof and apparatus for making the same
Inventor: CRYDERMAN ROBERT L
IPC: E01B5/02
Filed: 1990-11-30
Abstract: A superior unitary one quarter mile long railroad rail and system and method for manufacturing the same. The method of manufacture is characterized by the use of a continuous rolling process and the in-line controlled cooling of the rail. The system produces very long rails without any weld seams.
Patent CZ-345892-A3 (CZ)
Title: Gas-cooled electric machine
Inventor: ZIMMERMANN HANS
IPC: H02K9/18
Filed: 1992-11-23
Abstract: In the case of gas-cooled electrical machines having a stator (3) and a rotor (6) on which an axial fan (9) is arranged, the cooling gas flows (seen in the circumferential direction) in a non-uniform manner into the winding-overhang space (13). If an annular air-guidance device (1) with guide vanes (17) is provided in front of the axial fan (9) (seen in the flow direction of the cooling gas) and coaxially with respect thereto, and if the flow cross-section for the cooling gas flowing through the air-guidance device (1) is reduced in the main direction of the inlet flow on a part of the outer circumference of the air guidance device (1), by means of a cover (23), then the cooling effect becomes more uniform and the axial fan (9) is better utilised. …<IMAGE>…
Patent CZ-902688-A3 (CZ)
Title: split clamping cone for anchoring prestressing reinforcement
Inventor: KORENEK MIROSLAV ING
IPC: E04C5/12
Filed: 1988-12-29
Abstract: The split camping cone (1) for anchoring the pre-stressing reinforcement (7) of pre-stressed constructions, in particular seven-wire cords, is divided by radial cuts into segments (1a, 1b, 1c) mutually connected on the bottom of the partial cuts (9) by joining bridges (4) with a triangular cross-section. The joining bridges (4) hold the individual segments (1a, 1b, 1c) of the clamping cone (1) next to one another until breaking during assembly. The triangular area of the joining bridge (4) has an axial side (a) equalling a maximum of one fifth of the length (L) of the clamping cone (1) and its sloped side (c), which is the bottom of the dividing cross-section (9), has an angle with the axis (o) of the clamping cone (I) (β) of at least 2 degrees.<IMAGE>
Patent CZ-112796-A3 (CZ)
Title: Olefin polymerization catalyst and olefin polymerization process
Inventor: DALL OCCO TIZIANO
IPC: C08F210/16
Filed: 1995-07-18
Abstract: Catalysts for the polymerization of olefins are disclosed, which comprise the reaction product of: (A) a bridged and/or substituted cyclopentadienyl compound of titanium, zirconium or hafnium; (B) an organometallic aluminum compound of the formula (II) Al(CH2-CR<4>R<5>R<6>)wR<7>yHz, wherein in the (CH2-CR<4>R<5>R<6>) groups, which are the same or different, R<4> is an alkyl, alkenyl or arylalkyl group having from 1 to 10 carbon atoms, R<5> is an alkyl, alkenyl, aryl, arylalkyl or alkylaryl group having from 3 to 50 carbon atoms which is different from a straight alkyl or alkenyl group and, optionally, R<4> and R<5> fused together can form a ring having from 4 to 6 carbon atoms, R<6> is hydrogen or an alkyl, alkenyl or arylalkyl group having from 1 to 10 carbon atoms, the R<7> substituents, same or different, are alkyl, alkenyl, aryl, arylalkyl or alkylaryl radicals containing from 1 to 10 carbon atoms and, optionally, can contain Si or Ge atoms, w is 1, 2 or 3, z is 0 or 1, y = 3-w-z; and (C) water. The molar ratio aluminum/water is comprised between 1:1 and 100:1. These catalysts show an improved activity with respect to known catalysts wherein an aluminum compound different from those of the above formula is used.
Patent CZ-145096-A3 (CZ)
Title: Guanidides of alkenylcarboxylic acids being substituted by fluorophenyl groups, process of their preparation and their use as a medicament or a diagnostic agent, as well as medicaments in which said compounds are comprised
Inventor: SCHWARK JAN-ROBERT DR
IPC: C07C277/08
Filed: 1996-05-20
Abstract: Fluorocinnamoyl guanidine cpds. of formula (I) and their salts are new. R1-R5 = H or F, provided at least one is F; R6, R7 = H, 1-8C alkyl, 3-8C cycloalkyl, or phenyl (opt. substd. by 1-3 of F, Cl, CF3, Me, OMe and NR9R10; R9, R10 = H, 1-4C alkyl or 1-4C perfluoroalkyl.
Patent CZ-152897-A3 (CZ)
Title: Belt conveyor conveyor belt support
Inventor: FROMM ALFRED
IPC: B65G39/16
Filed: 1995-11-29
Abstract: A conveyor belt support maintains a conveyor belt in a central position. Support rollers for the conveyor belt are provided. Additionally, an underside, edge portion of the conveyor belt acts on at least one conical alignment roller that extends transversely to a longitudinal direction of the conveyor belt, and acts to hold the conveyor belt in the central position. The rollers are supported by a rotary frame that is pivotable relative to a stationary base frame when the conveyor belt shifts sideways out of the central position. A hydraulic drive is provided for pivoting the rotary frame when the conveyor belt shift sideways. Two hydraulic pumps are provided, each driven by one of the alignment rollers to provide a pressurized hydraulic fluid to the hydraulic drive via a two-pressure valve. One of the pumps is driven with a rotational speed that depends on the amount of shifting of the conveyor belt. The fluid with the greater of the two pressures is provided to the hydraulic drive to cause the conveyor belt to pivot the rotary frame, thereby shifting the belt back toward the central position.
Patent CZ-196594-A3 (CZ)
Title: Multilayer sound-insulating and damping structural part
Inventor: ROLLER MANFRED
IPC: G10K11/172
Filed: 1994-08-12
Abstract: In the case of a multiple-layer building element, which acts in a sound-damping manner, a soft porous layer which is joined on one side to an essentially rigid carrier layer or is arranged on one such and is covered on the other side with a thin covering layer, consists essentially of foam material; it has a system of chambers (4) which are designed and arranged such that sound waves can enter into the chamber through entry openings (5) to the chambers through the thin covering layer (3) covering the entry openings, and the chamber walls, as a result of resonance, significantly reduce the sound wave energy in conjunction with the sound-absorbing effect of the soft porous layer (2). <IMAGE>