baber/WOPTO huggingface dataset:
Patent TW-202333670-A (TW)
Title: Compound for inhibiting and degrading irak4, and pharmaceutical composition and pharmaceutical application thereof
Inventor: ZHANG CHEN
IPC: A61K31/40
Filed: 2023-01-03
Abstract: The present invention relates to a compound represented by general formula (I) or a stereoisomer, deuterated compound, solvate, prodrug, metabolite, pharmaceutically acceptable salt or eutectic crystal thereof, an intermediate thereof, and use thereof in IRAK4-related diseases such as autoimmune diseases, inflammatory diseases or cancers. B-L-K(I).
Patent TW-202337058-A (TW)
Inventor: NG HOU T
IPC: H01L33/50
Filed: 2022-03-10
Abstract: A tool and a method for fabricating light emitting diode (LED) displays. The tool includes a first dispensing chamber to deliver a first color conversion precursor onto a workpiece. A first curing station cures the workpiece to form a first color conversion layer over a first set of LEDs on the workpiece. A first washing/drying chamber removes uncured portions of the first color conversion precursor from the workpiece and then dries the workpiece. A second dispensing chamber delivers a second color conversion precursor onto the workpiece. A second curing station cures the second color conversion precursor to form a second color conversion layer over a second set of LEDs on the workpiece. A second washing/drying chamber removes uncured portions of the second color conversion layer from the workpiece. Each of the chambers is independently sealable. A controller controls a workpiece transport system to move the workpiece sequentially between the chambers.
Patent UA-39521-A (UA)
Title: Appliance for formation of stable with respect to dissipation flow of hot gaseous outbursts
Filed: 2000-09-27
Abstract: Appliance for formation of stable with respect to dissipation flow of hot gaseous outbursts has fixed coaxially on the outlet of smoke pipe cylindrical nozzle equipped with inlet branch pipe, outlet aperture-diaphragm at one end and springy membrane on the other end. Inside the body of the nozzle, in front of the outlet aperture-diaphragm, bimetal membrane is fixed, its diameter is equal to the inner diameter of the body, equipped with movable cover. This invention relates to protection of environment and is intended for lowering level of pollution with gaseous outbursts of dead zones of surface atmospheric layer.
Patent UA-41822-A (UA)
Title: Спосіб відновного лікування первинної артеріальної гіпертензії на транзиторній та лабільній стадіях у дітей
Inventor: HORSHA OKSANA VIKTORIVNA
Filed: 2001-04-03
Abstract: Винахід відноситься до області медицини, а саме до педіатрії, та фізіотерапії, і може бути застосований для відновного лікування та профілактики первинної артеріальної гіпертензії на транзиторній та лабільній стадіях у дітей. В основу винаходу поставлена задача вдосконалення способу відновного лікування ПАГ у дітей на транзиторній та лабільній стадіях шляхом досягнення сумації гіпотензивного та седативного впливу рефлексо- та фітотерапії, а також корекції порушень обміну речовин за рахунок залучення патогенетичне обгрунтованого комплексу із соків лікарських рослин, що дозволяє поліпшити клінічний перебіг захворювання, досягти стійкої ремісії, передбачити розвиток ускладнень, тобто підвищити ефективність відновлювального лікування. Поставлена задача вирішується тим, що в способі лікування первинної артерільної гіпертензії у дітей на транзиторній та лабільній стадіях, відповідно до винаходу, проводять гармонізуючу методику електоропунктури біологічно активних точок загальнозміцнюючої та симтоматичної дії, після чого здійснюють щоденний самомасаж на стопах зон нирки, сечоводу та сечового міхура по 5 хвилин на зону протягом 2-3 місяців, при цьому з першого дня лікування призначають рослинний комплекс, який складається з соків червоного буряка, моркви та апельсину у співвідношенні 2:2:1, по 15-20 мл 3 рази на день через 2-3 години після їжі протягом 2-3 місяців. В порівнянні з прототипом, застосування запропонованого способу лікування підвищує ефективність терапії ПАГ у дітей на транзиторній та лабільній стадіях. Розроблена методика дозволила покращити перебіг захворювання, подальший прогноз, досягти зниження кількості рецидивів до 3,1% та стійкої нормалізації обміну сечової кислоти. Простота та доступність розробленого комплексу дозволяє рекомендувати його для застосування в амбулаторних умовах, що зменшить медикаментозне навантаження в процесі лікування та профілактики ПАГ у дітей.
Patent UA-44531-A (UA)
Inventor: PISHAK VASYL PAVLOVYCH
Filed: 2001-05-15
Abstract: The method of the diagnosis and prognosis of disturbances in renal function consists in the assessment of acid-excreting and ion-controlling functions. The functional activity of the kidneys is assessed taking into account the local and seasonal time.
Patent UA-44574-A (UA)
Inventor: KUPER IVAN MYKOLAIOVYCH
Filed: 2001-05-31
Abstract: The purpose of this invention is to develop a device for extracting liquid from a well. The invention can be used in the oil industry, specifically in the oil production. According to the invention, the proposed device contains a casing with a differential spring-loaded hollow plunger having sidewalls with radial channels, and the lower part with a seat for a check valve. This device provides a possibility to extract liquids from wells and create pressure onto the production seam, and, as a result, increase well capacity and oil output.
Patent UA-55336-A (UA)
Title: Laser device for ophthalmology
Inventor: PASIECHNIKOVA NATALIIA VOLODYMYRIVNA
Filed: 2003-01-20
Abstract: The laser device for the ophthalmology comprises the power supply and control unit, the laser, the ophthalmologic microscope equipped with the digital photo camera, and the slit illuminator. The laser, the microscope, and the illuminator share the same base. The laser and the slit illuminator are optically connected with the objective lens of the ophthalmologic microscope via the semitransparent prisms. The non-transparent rotational disk is mounted in front of the oculars of the ophthalmologic microscope. The illuminating light passes through 480 nm filter. Two 520 nm filters are mounted within the cartridges of the rotational disk. The digital photo camera is connected to the computer.
Patent AP-1226-A (AP)
Title: Process for the synthesis of hiv protease inhibitors.
Inventor: AL-FARHAN EMILE
IPC: C07D307/20
Filed: 1999-03-18
Granted: 2003-11-21
Abstract: An improved for the synthesis of (3S)-tetrahydro-3-furyl N-[(1S,2R)-3-(4-amino-n-isobutylbenzenesulphonamido)-1-benzyl-2-hydroxypropyl]carbamate comprising four steps from the compound of formula (A) and a novel intermediate thereto.
Patent DO-P2004000898-A (DO)
Title: Pirazoles como inhibidores de factor de necrosis tumoral
Inventor: BORCHERDING DAVID R
Filed: 2004-05-04
Abstract: La presente invención proporciona compuestos de la formula (I) y profármacos estéricos sales o solvatos farmacéuticasmente aceptables de compuestos de ese tipo; o profármacos estéricos de sales o solvatos de ese tipo; compasiciones farmacéutica que comprenden compuesto de ese tipo, su preparación y su uso farmacéutico en el tratamiento de estados de enfermedad que pueden modularse la inhibicion de quinasa p38 y/o factor de necrosis tumoral (TNF).
Patent DO-P2010000141-A (DO)
Title: Tratamiento de cancer de mama con un inhibidor de parp solo o en combinacion con agentes anti-tumorales
Inventor: SHERMAN BARRY
Filed: 2010-05-12
Abstract: En un aspecto, la presente invencion proporciona un metodo para tratar el cancer de mama que es negativo para al menos uno de ER, PR, o HER2, que comprende administrar a un sujeto al menos un inhibidor de PARP. En otro aspecto, la presente invencion proporciona un metodo para tratar el cancer de mama, que comprende administrar a un sujeto al menos un inhibidor de PARP en combinacion con al menos un agente anti-tumoral.
Patent EC-SP11010848-A (EC)
Title: Método y sistema para integrar una pluralidad de servicios de administración de edificios y servicios de automatización del hogar con una pluralidad de servicios de juegos múltiples con base en operaciones de red de acceso neutral
Inventor: HARI SHANKER SINGH
IPC: H04B10/2581
Filed: 2011-02-28
Abstract: Se describe un sistema de fibra única de juegos múltiples; el sistema comprende una fibra única para suministrar uno o más de sistema global de comunicación móvil (GSM), acceso múltiple por división de código (CDMA), interoperabilidad mundial para acceso de microondas (Wimax), sistema de posicionamiento global (GPS) basados en servicios implementados en uno o más de: moto de transferencia asíncrona (ATM), multiplexión por división de tiempo (TDM), protocolo de control de transmisión - protocolo de internet (TCP - IP), radio frecuencia (RF), multiplexión por división de longitud de onda (WDM) o multiplexión por división de longitud de onda densa (SWDM); y un dispositivo que se puede programar por computadora acoplado de hardware, acoplado con la fibra única para crear la pluralidad de túneles dentro de dicha fibra única y crear la pluralidad de circuitos dentro de dichos túneles.
Patent EC-SP11010857-A (EC)
Title: Nuevas benzamidas, su preparación y su uso como medicamentos
Inventor: HIMMELSBACH FRANK
IPC: C07D213/68
Filed: 2011-02-28
Abstract: Heteroariloxi-amidas de ácido benzoico sustituidas de la fórmula general I,en donde los radicales R1 a R7, así como X e Y se definen de acuerdo con la reivindicación 1, incluyendo sus tautómeros, sus estereoisómeros, sus mezclas y sus sales. Los compuestos según la invención son apropiados para el tratamiento de enfermedades de las vías aéreas, en especial EPOC y asma.
Patent EC-SP12011575-A (EC)
Title: Derivados de fenil(oxi/tio)alcanol
Inventor: Greul Jörg Nico
IPC: C07D249/08
Filed: 2012-01-05
Abstract: La presente invención se refiere a nuevos derivados de fenil(oxi/tio)alcanol, a procedimiento para producir estos compuestos, a agentes que contienen estos compuestos, así como a su uso como compuestos biológicamente activos, especialmente para el control de microorganismos dañinos en la protección de plantas y en la protección de materiales y como reguladores del crecimiento vegetal.
Patent GB-189702524-A (GB)
Title: Improvements in the Manufacture of Furniture Castor Rings.
Inventor: KEELING SAMUEL HENRY
Filed: 1897-01-30
Granted: 1897-12-11
Abstract: 2524. Keeling, S. H., and Picken, H. M. Jan. 30. M a k i n g furniture and like castors.-The two parts of castor rings are pressed or stamped by a succession of dies, or spun, from sheet-metal blanks to the forms shown in section in Figs. 3 and 5. The two parts are then engaged, and the flange b<1> is spun or pressed over the flange a<1> as shown in Fig. 2, thus making a ring with an outer bulge a<4> and an inner flange b<1>, a<1> for the chair leg and castor plate to bear on. In the Provisional Specification it was stated that the two parts might be connected by a third ring instead of turning the flange b<1> over a<1>.
Patent GB-189703886-A (GB)
Title: An Improvement relating to Soldering Appliances.
Inventor: BACON CHARLES EDMUND
Filed: 1897-02-13
Granted: 1897-06-19
Abstract: 3886. Bacon, C. E. Feb. 13. Soldering.-The soldering-bit B is a cylindrical piece of copper provided with two projections C. The bit is heated by inserting it through a heated sleeve A, the projections C being passed along the grooves E, turned through 90‹ in the grooves G, and drawn back into grooves F.
Patent GB-189704840-A (GB)
Title: A Method of and Apparatus for Testing Drain and other Pipes.
Inventor: MOSES LIONEL
Filed: 1897-02-23
Granted: 1897-05-01
Abstract: 4840. Moses, L. Feb. 23 Testing.-Volatile chemicals, such as ammonia and hydrochloric acid, are placed in dishes a in a chamber A from which the fumes are expelled by a fan B into the pipes to be tested.
Patent GB-189708920-A (GB)
Title: Improvements in or relating to Match Packing or Boxing Machines.
Inventor: LAGERMAN ALEXANDER
Filed: 1897-04-07
Granted: 1897-08-14
Abstract: 8920. Lagerman, A. April 7. Measured quantities, delivering. -A machine for filling match boxes is shown in vertical section in Fig. 1. The matches are pressed forwards from a hopper E by a loose corrugated plate E<1>, and are separated in quantities suitable for filling the boxes by shutters F, which are periodically closed upon the matches by the action of springs and opened by means of a cam D<6> on a countershaft D<1>, and levers F<5>, F<4>, and F<3> connected to crank shafts F<1> upon which the shutters are mounted. The hopper is provided with several outlets, every one of which is provided with a matchmeasuring mechanism of the kind described above. Beneath each pair of shutters F is a rising and falling plate G, mounted upon a frame G<2>, which is actuated by a rod and cam on the shaft D<1>. The matches fed to one of the plates G are lowered and then pushed by a plunger into a chamber I, attached to a frame I<1>, which is moved up and down by a cam D<8>. The cells I are partly bounded by movable ends K, mounted on a frame K<1>, actuated by an arm K<2> and cam D<9> on the shaft D<1>. Within the cells I are mounted hinged flaps P, I<3> which are held down by springs against the matches as these are being pushed forwards. When the matches are raised by the frame I' into the upper parts of the chambers I, their untipped ends bear against the corrugated ends of movable bars L which are attached to a bar which is shaken by means of the levers L<2>, L<3> and cam D<4>. After the matches have been lowered again by the descent of the frame I', they are pushed by the plunger over an automatically - sliding plate N, which guides the matches as they pass into the box. The outer case of each match box is almost completely drawn off the inner case or drawer, before the latter is filled, by a hook M, carried by a frame M', which is actuated by an arm M' and cam on the shaft D<1>; the outer case is pushed back after the filling by a plunger M<3>, actuated by a spring M<5>. The filled boxes are carried away by a horizontal endless travelling chain o, and are finally pushed by the empty boxes into a trough opposite the box hopper, The drawers to be filled, inserted within their outer cases, are supplied to the filling-mechanism by a chain from a hopper near which is a plunger which partially pushes the drawers from the outer cases. The chain is made of plates each of which holds several boxes, which are held against an edge plate projecting from every link of the chain ; an arrangement is provided for regulating the number of boxes fed from the hopper. A leather-covered or like brush C<1>, which is reciprocated vertically by means of a frame C and eccentrics B<5> on the main shaft, serves to direct the matches from the hopper E down the several chutes of the hopper.
Patent GB-189709603-A (GB)
Title: Improvements in Air-pumps or Tyre-inflators attached to Cycles.
Inventor: HARVEY CHARLES
Filed: 1897-04-15
Granted: 1898-03-12
Abstract: 9603. Harvey, C., and Westwood, F. April 15. Inflating, pumps for. Relates to pumps always attached to a velocipede; various ways of actuating them are described. In double-acting pumps the air passes through grooves a<2> in the piston past the cup-leather packing into the cylinder ends, and is expelled through valves and a nozzle d<6> on the piston. The piston is actuated by a rotating crank f<5> and a connecting-rod e ; the crank may turn about the gudgeon d<11>, in which case the rod e is pivoted at f<3> and acts as a radius link. In another arrangement, the rod e is worked by a lever. In the arrangement shown in Fig. 10, the pin h<2> of the crank disc h<3> carries a pinion h<1>, which gears with a fixed toothed annulus h<7>; a link h attached to the piston works on a sleeve on the pinion, which as it revolves causes the piston to reciprocate. A single-acting pump is described actuated by togglelevers between the piston and the end of the barrel. A nut with a steep thread may turn on the barrel of the pump and engage projections on the piston which pass through slots in the barrel.
Patent GB-189709895-A (GB)
Title: Improvements in and relating to Machines for Automatically Cutting, Folding and Winding Strips of Flexible Material.
Inventor: ADAMS ABRAHAM LINCOLN
Filed: 1897-04-20
Granted: 1897-07-24
Abstract: 9895. Adams, A. L., and Hawes, G. E. April 20. Folding paper.-Flexible material is cut into strips, folded longitudinally at the edges, and wound in the form of spools. The material is cut into strips by cutters on a pair of rollers 8, 9, and the strips are passed between rollers 13, 14 fitted with collars, the collars on one roller being at a distance apart equal to the width of the folded strip, while those of the other are opposite the spaces between the collars of the first. The edges of each strip are by these means, and by the tension which is put upon the strip, caused to fold on to the main body of the strip, the folds being pressed firmly together between the roller 14 and an adjustable roller 19, the latter roller having collars which are equal in width to that of the folded strips, and take between the collars on the roller 14. The strips now pass round a guide-roller 26 to the winding roller or drum 58. This drum is formed of a number of longitudinal fingers or ribs, which are supported in conical journals and may be caused to expand or collapse by operating an internal screw fitted with a band-wheel. The drum is mounted upon a swinging frame 42, which rises as the winding proceeds, the frame being prevented from falling back by a ratchet bar or rack 44, which is drawn forwards by a spring 47. The machine is driven through a friction disc arrangement, so that the winding will not take place too rapidly. In front of the table, the material passes over and under a number of bars 79, of which one set is fixed and the other is carried by a pivoted frame or lever 78, which is connected by a rod 72<a> and a suitable lever system with a catch by which the spring belt fork rod is prevented from moving the driving-strap on to the loose pulley. Should the supply of material become exhausted, the frame 78 falls and the machine is automatically stopped ; 95 is a stopping-handle and 88 is a starting-lever.
Patent GB-189711021-A (GB)
Title: Improvements in Cycle-roundabouts.
Inventor: JOKISCH CARL HERMANN
Filed: 1897-05-03
Granted: 1897-08-14
Abstract: 11,021. Jokisch, C. H. May 3. Roundabouts.-A cycle roundabout is formed of a central column a supporting a cover b, and having a ball-bearing c on which a rotary disc d, carrying a number of arms e, is attached. These arms receive adjustable rods h terminating in one or more forks k to which one or more bicycles are attached by a movable coupling.
Patent GB-189712684-A (GB)
Title: Improvements in or relating to Ladies' Cycling Skirts.
Inventor: SWINGLER WILLIAM HOWARD
Filed: 1897-05-22
Granted: 1898-05-07
Abstract: 12,684. Swingler, W. H., and Hooydonck, H. van. May 22. Skirt clips, cyclists' and like. - A band A, which may be of perforated cloth lined with gauze, has its ends connected by elastic straps so that it can be placed on the leg near the knee, and carries a strap C and one part of a clasp fastening D, the other part of which is attached to the skirt F. The fastener may be that described in Specification No. 12,683, A.D. 1897. The band A may be entirely elastic, and the strap C may be interposed between the skirt and the fastener. The Provisional Specification describes a knee-cap attached by an elastic band to the skirt.
Patent GB-189716287-A (GB)
Title: Improvements in and relating to Foot Rests for Velocipedes and the like.
Inventor: LEA WILLIAM CHATER
Filed: 1897-07-09
Granted: 1898-05-20
Abstract: 16,287. Lea, W. C. July 9. Forks ; foot-rests. -The open ends of the front forks of velocipedes are closed by a spring cap a, preferably of the kind described in Specification No. 17,192, A..D. 1895, which carries the foot-rests b.
Patent GB-189718255-A (GB)
Title: Improvements in Pumps.
Inventor: STEIN JACOB
Filed: 1897-08-05
Granted: 1898-01-22
Abstract: 18,255. Stein, J., [Jacomet, Z.]. Aug. 5. Actuating pumps; pump barrels and cylinders.- The oscillation of the shaft K is transferred to the double piston B, which reciprocates in the cylinder a', by a toothed segment and rack. When the shaft K rotates continuously it carries an eccentric which works in a slot in the piston. The casing is in two parts joined at a, and the suction and delivery valves are connected with the detachable castings D and E respectively. The pump is suitable for hand or power.
Patent GB-189721148-A (GB)
Title: An Improved Hand Forging Apparatus for Blacksmiths' use.
Inventor: STARK WILLIAM BURT
Filed: 1897-09-15
Granted: 1898-06-25
Abstract: 21,148. Stark, W. B. Sept. 15. Forging.-Hand forging-apparatus for blacksmiths' use is constructed with a base-plate b bolted to a table e and a lever c, c<1> pivoted to the baseplate b at a and carrying weights g, g<1>. The bottom dies or tools are fixed in the base b, and the top dies in the lever c<1>, which is guided by the quadrant arm m. The tools or dies may be formed in one piece with the lever c<1> and base-plate b.
Patent GB-189726561-A (GB)
Title: Improvements in, and in connection with Brushes.
Inventor: ASHDOWN GEORGE EDWARD
Filed: 1897-11-13
Granted: 1898-04-16
Abstract: 26,561. Ashdown, G. E. Nov. 13. Bristles.-An extra tuft of bristles D is fixed at the end of the handle of a banister, dusting, or other brush.
Patent GB-189802503-A (GB)
Title: Manufacture of Green Colouring Matters for Dyeing Wool.
Inventor: WEIL HUGO
Filed: 1898-01-31
Granted: 1899-06-14
Abstract: 2503. Weil, H. Jan. 31. Dyes, artificial.-Colouring-matters of the malachite-green series, suitable for dyeing wool, are obtained by either of the following processes:- (1) Condensing p-nitrobenzaldehyde-o-sulphonic acid with two molecular proportions of ethyl- or methylbenzylaniline, carefully sulphonating the product so as to introduce only one sulpho group, precipitating the leuco disulphonic acid thus produced by pouring the mixture into water, and, after filtering off and washing the precipitate, oxidizing it with lead peroxide or other suitable oxidizing-agent : (2) condensing one molecular proportion of p-nitrobenzaldehyde-o-sulphonic acid in the presence of alcohol with a mixture of one molecular proportion of ethyl- or metbylbenzylaniline sulphonic acid and one molecular proportion of ethyl- or methyl-benzylaniline, dissolving the product in a dilute solution of carbonate or acetate of soda, and separating the leuco disulphonic acid by the addition of dilute sulphuric acid ; (3) employing p-chlorobenzaldehyde-osulphonic acid instead of p-nitrobenzaldehyde-osulphonic acid in the preceding processes. p-Nitrobenzaldehyde-o-sulphonic acid is prepared by the oxidation of p-dinitrostilbene o-disulphonic acid with potassium permanganate or by transforming mononitrated-o-chlorobenzylchloride into nitroo-chlorobenzaldehyde and treating the product with sodium sulphite. p-Chlorobenzaldehyde-o-sulphonic acid is obtained by replacing the amido groups in p diamidostilbeneo-disulphonic acid by chlorine, and oxidizing the product with potassium permanganate.
Patent GB-189811426-A (GB)
Title: Improvements in Electrically Propelled Vehicles.
Inventor: BROUGHAM REGINALD THOMAS DUDLE
Filed: 1898-05-19
Granted: 1899-03-25
Abstract: 1 1 , 4 2 6 . Brougham, R. T. D., and Bersey, W. C. May 19. Motor road vehicles.-Relates to vehicles having two independent wheels driven by separate electric motors. The object is to enable the inner wheel to cease driving when the vehicle is being turned. For this purpose a rotary switch is employed which in its central position supplies current to both motors, but when turned in one direction or the other cuts off the current from one or other of the motors. Fig. 1 shows the switch plate a engaging with the spring contacts e, f, g. The switch is operated by projections r, s from the fore carriage t acting on pins i,j, k. A spring m is provided for rapidly throwing over the switch towards one side or the other, whenever it is displaced from its central position. A spring and ball p entering a recess in the switch plate are provided for normally holding the switch centrally.