baber/WOPTO huggingface dataset:
Patent DE-69132291-D1 (DE)
Title: Xanthinderivate
Inventor: SMITH GLYNN
IPC: A61P37/08
Filed: 1991-12-19
Granted: 2000-08-10
Abstract: PCT No. PCT/GB91/02286 Sec. 371 Date Jul. 7, 1993 Sec. 102(e) Date Jul. 7, 1993 PCT Filed Dec. 19, 1991 PCT Pub. No. WO/9211260 PCT Pub. Date Jul. 9, 1992.    <IMAGE>  (I)   <IMAGE>  (b)    A compound of formula (I) or, if appropriate, a pharmaceutically acceptable salt thereof, wherein R1 and R2 each independently represent an alkyl group or a moiety of formula (a): -(CH2)m-A, wherein m represents zero or an integer 1, 2 or 3 and A represents a substituted or unsubstituted cyclic hydrocarbon radical; R3 represents hydrogen, NO2 or a halogen atom, an alkoxy group or a group of formula NRsRt wherein Rs and Rt each independently represent hydrogen or alkyl or Rs and Rt together with the nitrogen to which they are attached form a phthalimido group, the phthalimido group being substituted or unsubstituted in the phenylene moiety or R3 represents a moiety of formula (b), wherein R5 represents substituted or unsubstituted alkyl or a substituted or unsubstituted aryl group; and R6 represents hydrogen or a group SO2R7 wherein R7 represents substituted or unsubstituted alkyl, a substituted or unsubstituted aryl group; R4 represents SO2R8, wherein R 8 represents substituted or unsubstituted alkyl or a substituted or unsubstituted aryl group, or, when R3 represents a moiety of the above-defined formula (b), then R4 represents hydrogen or a substituted or unsubstituted alkyl group or a benzyl group substituted or unsubstituted in the phenyl ring a process for preparing such a compound, a composition comprising such a compound and the use of such a compound and composition in medicine.
Patent DE-69200011-D1 (DE)
Inventor: CORNIER GERARD
IPC: C03C3/078
Filed: 1992-02-19
Granted: 1993-10-14
Abstract: Glass composition which has the characteristic properties of crystal, namely a relative density of at least 2.90, a refractive index of at least 1.545 and a characteristic sonority and a high clarity, but containing no toxic element and especially neither lead nor barium, characterised in that it contains, as weight percentage:     53.0 to 58.0 of silica SiO2   6.0 to 10.0 of potassium oxide K2O   4.5 to 7.5 of sodium oxide Na2O   0.0 to 9.00 of calcium oxide CaO   0.0 to 12.00 of strontium oxide SrO   16.0 to 21.0 of zinc oxide ZnO   0.5 to 1.5 of antimony oxide Sb2O3   0.0 to 1.5 of aluminium oxide Al2O3   0.0 to 2.5 of tin oxide SnO2   0.0 to 1.2 of boron oxide B2O3   0.0 to 3.0 of lanthanum oxide La2O3   0.0 to 2.0 of titanium oxide TiO2   0.0 to 0.3 of lithium oxide Li2O the sum of the oxides of calcium, strontium and zinc being between 26.5 and 31 % with, as additional conditions:     - when SrO = 0  CaO can range up to 9   - and when SrO  NOTEQUAL  0, CaO is between 0 and the remainder to 31, decreased by SrO + ZnO.
Patent DE-69206245-D1 (DE)
Inventor: MARCHI EGIDIO
IPC: A61K9/12
Filed: 1992-08-10
Granted: 1996-01-04
Abstract: Vaginal pharmaceutical compositions administrable through the topical route, particularly in the form of vaginal foams and ointments containing a therapeutically effective amount of rifaximin (Common International Denomination) are useful in the treatment of vaginal infections, particularly bacterial vaginosis.
Patent DE-69206357-D1 (DE)
Inventor: PRINZ FRITZ B
IPC: B23K9/02
Filed: 1992-07-29
Granted: 1996-01-11
Abstract: In a method and apparatus for forming a three-dimensional object, successive layers (2) of metal are welded together to build the object. After each weld deposited layer (2) is formed, a complementary material (6) is placed adjacent the layer. In this manner, layers of material form a block of welded metal and complementary material. Then, all or a portion of the complementary material (6) which serves as a support structure during forming, can be removed. The welded layers (2) are milled to a final shape either after each layer (2) is formed or after all layers (2) have been made. Existing CNC machines (20) can be easily modified to practice the method. <IMAGE>
Patent DE-69217918-D1 (DE)
Inventor: JONES DAVID
IPC: B01J8/38
Filed: 1992-10-28
Granted: 1997-04-10
Abstract: A shield, such as an upstanding cylindrical partition, is mounted adjacent to an air source, such as an air distribution plate/screen of a Wurster system processor, whereby the open upper end of the partition is generally horizontally registered with and disposed about the upper extremity of an associated spray nozzle. The open lower end of the inner cylindrical partition is generally sealed relative to the air distribution plate/screen and operative to receive air upwardly therethrough for subsequent passing through the inner partition about the spray nozzle. The upper end of the inner tubular partition shields the initial spray pattern discharged from the spray nozzle and prevents the premature entrance of particles moving into the spray nozzle area.
Patent DE-69221852-D1 (DE)
Inventor: FORREST JAMES
IPC: C23C4/12
Filed: 1992-03-05
Granted: 1997-10-02
Abstract: A method and apparatus for the production of a deposit such as a bar (1) is provided. The deposit has a longitudinal outer surface (2) and a front face deposition surface (3). The spray deposition comprises atomized droplets produced by outer and inner sprays (4 and 5). The outer and inner sprays (4 and 5) are both directed such that, during deposition, a substantial proportion of droplets from both sprays are deposited on the front face (3) of the forming deposit. The inner spray (5) has a higher gas to metal ratio than the outer spray allowing an increase of both deposition and final product yield.
Patent DE-69227471-D1 (DE)
Inventor: OLSEN HANS
IPC: A61F5/448
Filed: 1992-08-31
Granted: 1998-12-03
Abstract: PCT No. PCT/DK92/00258 Sec. 371 Date Feb. 28, 1994 Sec. 102(e) Date Feb. 28, 1994 PCT Filed Aug. 31, 1992 PCT Pub. No. WO93/04646 PCT Pub. Date Mar. 18, 1993.A convex adapter for use in connection with ostomy equipment comprises a ring-shaped member (10, 15, 18). The ring-shaped member (10, 15, 18) comprises a central, relatively rigid ring (10) with a convex face (12) as well as a peripheral, relatively flexible part (15) extending considerably longer and radially than the relatively rigid ring (10).
Patent DE-69232484-D1 (DE)
Inventor: COLLE ROBERTO
IPC: C07D495/04
Filed: 1992-07-01
Granted: 2002-04-18
Abstract: PCT No. PCT/EP92/01483 Sec. 371 Date Jan. 5, 1994 Sec. 102(e) Date Jan. 5, 1994 PCT Filed Jul. 1, 1992 PCT Pub. No. WO93/01186 PCT Pub. Date Jan. 21, 1993.     <IMAGE>  (I)    Compounds of formula (I) in which, R is linear or branched alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, aryl, aralkyl or furan-2-yl alkyl; R1 and R2, which may be the same or different, are each hydrogen, hydroxy, alkoxy, or halogen; R3 is hydrogen, hydroxy or alkoxy; "Het" is optionally substituted single or fused heteroxyclic ring, containing from 5 to 10 ring atoms and comprising up to four heteratoms in the or each ring, selected from oxygen, nitrogen and sulphur; R4 and R5, which may be the same or different, are each hydrogen alkyl, halogen, nitro; CF, cyano, alkoxy carbonyl, NH, alkylcarbonylamino, hydroxy, alkoxy, or benzyl, are selective delta receptor agonists and are useful in the treatment of pain.
Patent DE-69301253-D1 (DE)
Inventor: NI FONG-MING
IPC: A45B25/18
Filed: 1993-02-10
Granted: 1996-02-22
Abstract: A method for forming a cover (85) of an umbrella including preparing several pieces of cloth (41), clamping the perimeters of the cloth (41) and pulling the cloth (41) downward against a lower mold (69) having a convex shape, heating the lower mold (69) in order to soften the cloth (41), moving an upper mold (70) downward to clamp the cloth, heating the lower mold (69) again in order to further increase the temperature of the lower mold (69) so that the cloth (41) can be hot-pressed, cooling the lower mold (69), removing the cloth (41), and cutting the perimeter of the cloth so as to form the cover (85) of the umbrella. <IMAGE>
Patent DE-69311619-D1 (DE)
Inventor: PIANI SILVANO
IPC: C08B37/10
Filed: 1993-03-10
Granted: 1997-07-24
Abstract: The synthesis of new semi-synthetic glycosaminoglycans with heparin or heparan structure of  alpha -L-iduronic-2-O-sulfate acid modified in position 2 is described in which the sulfate group is, entirely or in part, substituted with a nucleophilic radical. These new semi-synthetic glycosaminoglycans of general formula IV <CHEM> have good pharmaceutical properties in that they may also be absorbed orally and have good anti-thrombotic activity accompanied by low risk of haemorrhage and reduced anti-coagulating activity.
Patent DE-69312066-D1 (DE)
Inventor: KEITH ROBERT DUNCAN FALCONER
IPC: G16H40/63
Filed: 1993-06-09
Granted: 1997-08-14
Abstract: PCT No. PCT/GB93/01231 Sec. 371 Date Jan. 24, 1995 Sec. 102(e) Date Jan. 24, 1995 PCT Filed Jun. 9, 1993 PCT Pub. No. WO93/25971 PCT Pub. Date Dec. 23, 1993A medical signal analyzer comprises a sensing device (1) including at least one sensor for monitoring at least one parameter derived from a physiological measurement taken from a patient under observation, a data collection device (2), coupled to the sensing device for receiving and sampling an output signal of the sensing device and generating digital signals representative of the parameter over a predetermined time interval, a data analysis means (4) comprising means operable to recognize in the digital signals received over a signal link from the data collection device a plurality of predetermined information features, and means for classifying at least one of the said features, to produce first output signals representative of the existence of such features and representative of feature classifications, signal storage means (6) arranged to receive and store the said first output signal as a short term knowledge base, database storage means for storing reference data as a long term knowledge base (10), an inference engine arranged to process signals representative of the short term and long term knowledge bases automatically to produce conclusion signals, and indication means (16) coupled to receive signals produced by the inference engine to provide an indication of said conclusion signals.
Patent DE-69316353-D1 (DE)
Inventor: PONCET PHILIPPE
IPC: A61B17/28
Filed: 1993-04-13
Granted: 1998-02-19
Abstract: A surgical device comprising (a) a tubular housing having a longitudinal bore extending therethrough, (b) a first elongate member extending through the longitudinal bore of the housing, and having a proximal and a distal segment, where at least part of the distal segment comprises an elastic material, especially a super elastic material, and wherein the distal segment assumes a first shape when extended from the longitudinal bore, and a second shape when withdrawn into the bore, (c) a second elongate member also having a proximal and a distal segment, the second elongate member extending substantially parallel to the first elongate member so that it is moved by the first elongate member, when the first elongate member changes from its first to its second shape and vice versa, the second elongate member being rotatable relative to, and substantially about, the axis of the first elongate member, and (d) an operating head secured to the distal segment of the second elongate member so that it (i) is moved with the second elongate member when the first elongate member changes from its first to its second shape and (ii) can be rotated by the second elongate member substantially about the axis of the first elongate member.
Patent DE-69321837-D1 (DE)
Inventor: CRAINIC SORIN
IPC: A61F13/56
Filed: 1993-07-16
Granted: 1998-12-03
Abstract: In a sanitary napkin (10), the retention layer (34) of the absorbent core is covered by a first tissue sheet of a density between 0.01 g/cm3 and 0.1 g/cm3 and by a second tissue sheet of a density between 0.08 and 0.3 g/cm3, the difference in density between the tissue sheets being between 0.01 g/cm3 and 0.2 g/cm3. The density gradient on top of the retention layer (34) results in a relatively high efficiency of the retention layer (34) and in efficient draining of the topmost tissue sheet, so that chances of rewet are reduced.
Patent DE-69322988-D1 (DE)
Inventor: BERNET THIERRY
IPC: F27B3/28
Filed: 1993-02-19
Granted: 1999-02-25
Abstract: For regulating the combustion air flow-rate of a device (1) for collecting the fumes of a metallurgical reactor (2) comprising a combustion chamber (4) fed with air through a fan (9) of variable flow-rate, a set-point value C0 for the oxygen content in the fumes in the exhaust pipeline (5) is set, the oxygen content M1 of the fumes at the outlet of the combustion chamber (4) is measured, using C0 and M1, a set-point C1 of variation in the combustion air flow-rate is calculated, a parameter representative of sharp variations in unburnt gas flow-rate at the outlet of the metallurgical reactor (2) is measured, and a combustion air flow-rate set-point C2 is calculated for obtaining complete combustion of the unburnt gases in the fumes; the values C1 and C2 are added to obtain a combustion air flow-rate set-point which is sent to the regulation of the fan (9); these calculations can be carried out with electronic means (14, 15, 16). <IMAGE>
Patent DE-69332312-D1 (DE)
Inventor: HAAKE DAVID A
IPC: C07H21/04
Filed: 1993-03-31
Granted: 2002-10-24
Abstract: An antigenic preparation is provided which contains a 31 Kd outer membrane protein from Leptospira which can be used immunologically as a vaccine for leptospirosis caused by this organism.
Patent DE-69333914-D1 (DE)
Inventor: HANG JAN H
IPC: C12R1/91
Filed: 1993-09-28
Granted: 2005-12-29
Abstract: Embodiments of the present invention feature methods and compositions for controlling the translation of viral peptides and proteins from viral nucleic acid, with particular applications to pestivirus and HCV. The methods and compositions feature control elements of the 5'UT region of the viral genome.
Patent DE-69404624-D1 (DE)
Inventor: RENAUT PATRICE
IPC: A61K31/17
Filed: 1994-12-26
Granted: 1997-09-04
Abstract: 15-deoxy-spergualin analogues of formula (I) and their addn. salts are new. X = (CH2)n; Y = (CH2)4; T = (CH2)2; A = a single bond, -CH2-, -CH2O-, -CH2NH-, -CH(OH)-, -CHF-, or -CH(OCH3)-; n = 6-8. Intermediate cpds. of formula (II) are also claimed. A has the values above or in addn. is CH(OCH2C6H5); R1, R2, R3 = amino-protective gps. of alkoxycarbonyl, benzyloxycarbonyl or benzyl type.
Patent DE-69411797-D1 (DE)
Inventor: OMATSU TOSHIHIRO
IPC: B01J31/18
Filed: 1994-04-18
Granted: 1998-08-27
Abstract: In hydroformylation comprising allowing an ethylenically unsaturated compound to react with carbon monoxide and hydrogen in the presence of a catalyst to convert it into a corresponding aldehyde, the catalyst is a rhodium-containing catalyst comprising;     (a) a rhodium compound; (b) an organic phosphorus compound having at least one tertiary amine residual group and at least one tertiary phosphorus residual group, having the ability of coordination to said rhodium compound; and optionally (c) an acidic compound with which at least part of the tertiary amine residual group of the organic phosphorus compound is converted into ammonium ions.
Patent DE-69414031-D1 (DE)
Inventor: LEAKE CRAIG H
IPC: C09J103/02
Filed: 1994-05-31
Granted: 1998-11-26
Abstract: A starch-based, water resistant alkaline corrugating adhesive composition free of formaldehyde and other crosslinking and water resistance additives comprising an ungelatinized starch which contains high amylose starch having greater than 60% by weight of total amylose content and present in sufficient amount to provide at least 15% by weight of amylose content based on the total starch content in the adhesive.
Patent DE-69428831-D1 (DE)
Inventor: BERRUTO ERMANNO
IPC: H04W72/04
Filed: 1994-05-11
Granted: 2001-12-06
Abstract: In a radio communication system, in particular a mobile communication system, variable-rate information flows originating from different sources (CV1, CS1; CV2, CS2) and relative to a same communication are transmitted on a same radio channel. Each mobile station (M1...Mh) and the fixed part (B1...Bn; RNC) of the system comprise a unit for the control of the variable-rate transmission, which dynamically allocates the available bits to the different streams by taking into account the needs of the sources (CV1, CS1; CV2, CS2), the conditions of the channel (6) and the system occupancy. <IMAGE>
Patent DE-69503904-D1 (DE)
Inventor: NORCINI GABRIELE
IPC: A61P9/00
Filed: 1995-06-16
Granted: 1998-09-10
Abstract: PCT No. PCT/EP95/02343 Sec. 371 Date Nov. 27, 1996 Sec. 102(e) Date Nov. 27, 1996 PCT Filed Jun. 16, 1995 PCT Pub. No. WO95/35302 PCT Pub. Date Dec. 28, 1995Compounds of formula (I),    <IMAGE>  (I)  wherein R is a biphenyl group optionally substituted, by one or more substituents, the same or different selected among halogen atoms, hydroxy groups, alkoxy, alkyl thioalkyl or alkoxycarbonyl groups having from 1 to 6 carbon atoms in the alkyl moiety, C1-C3 alkyl groups containing one or more fluorine atoms, carboxy groups, nitro groups, amino or aminocarbonyl groups, acylamino groups, aminosulphonyl groups, momo- or di-alkylamino groups having from 1 to 6 carbon atoms in the alkyl moiety, mono- or di-alkylamino-carbonyl groups having from 1 to 6 carbon atoms in the alkyl moiety; R1 is a hydrogen atom, a straight or branched C1-C6 alkyl group or an arylalkyl group having from 1 to 6 carbon atoms in the alkyl moiety wherein the aryl is a phenyl, a biphenyl, a napthyl or a 5 or 6 membered aromatic heterocycle with one or two heteroatoms selected among nitrogen, oxygen and sulphur, optionally substituted with one or more substituents, the same or different, selected among halogen atoms, hydroxy groups, alkoxy, alkyl, thioalkyl or alkoxycarbonyl groups having from 1 to 6 carbon atoms in the alkyl moiety, C1-C3 alkyl groups containing one or more fluorine atoms, carboxy groups, nitro groups, amino or aminocarbonyl groups, acylamino groups, aminosulphonyl groups, mono- or di-alkylamino groups having from 1 to 6 carbon atoms in the alkyl moiety, mono- or di-alkylaminocarbonyl groups having from 1 to 6 carbon atoms in the alkyl moiety; R2 is a straight or branched C1-C6 alkyl group, optionally containing one or more fluorine atoms or one or more -NH- groups, an arylalkyl, an arylcarbonylaminoalkyl, an arylalkylcarbonylaminoalkyl or an arylaminocarbonylalkyl group having from 1 to 6 carbon atoms and optionally one or more -NH- groups in the alkyl moiety, the aryl being optionally substituted by one or more substituents, the same or different, selected among halogen atoms, hydroxy groups, alkoxy, alkyl, thioalkyl or alkoxycarbonyl groups having from 1 to 6 carbon atoms in the alkyl moiety, C1-C3 alkyl groups containing one or more fluorine atoms, carboxy groups, nitro groups, amino or aminocarbonyl groups, acylamino groups, aminosulphonyl groups, mono-or di-alkylamino groups having from 1 to 6 carbon atoms in the alkyl moiety, mono- or di-alkylaminocarbonyl groups having from 1 to 6 carbon atoms in the alkyl moiety; m is 0 or 1; X is a hydrogen or fluorine atom; the carbon atom marked with an asterisk is an asymmetric carbon atom; and their pharmaceutically acceptable salts, are described. The compounds of formula (I) are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
Patent DE-69504002-D1 (DE)
Inventor: RIJKEN JACOBUS
IPC: B65G51/06
Filed: 1995-09-19
Granted: 1998-09-17
Abstract: The invention relates to a cartridge for application in a pneumatic dispatch conduit system, with a basically hollow cylindrical body (1) comprising at at least one end a closable access opening (2). The access opening (2) is defined by at least one segment (3) which is pivotable between a closure position and an opening position. Further means are applied for automatically pivoting the segment (3) towards the opening position when the cartridge with its respective end is free from the pneumatic dispatch conduit system. For realizing said means it is possible that the segment (3) is spring-loaded towards its opening position. <IMAGE>
Patent DE-69509488-D1 (DE)
Inventor: GOVONI GABRIELE
IPC: C08F4/60
Filed: 1995-07-18
Granted: 1999-06-10
Abstract: Multistage process for the polymerization of olefins CH2=CHR, where R is hydrogen or an alkyl, cycloalkyl or aryl radical with 1-10 carbon atoms, comprising two stages of polymerization. In a first stage, in the presence of a titanium or a vanadium catalyst and working in one or more reactors, an olefinic polymer with particular values of porosity is prepared; in a second stage, in the presence of the said porous polymer and a metallocene compound and/or their reaction products, one or more olefins, that are equal to or different from those polymerized in the first stage, are polymerized in one or more reactors.
Patent DE-69515006-D1 (DE)
Inventor: VAN DER ZON GERARDUS PETRUS AN
IPC: B62B3/10
Filed: 1995-11-21
Granted: 2000-03-16
Abstract: Trolley for transporting containers with loose goods, provided with a bottom frame with wheels, and on to that a vertical partitioning. The upright partitioning has hook-shaped elements (6) with downward facing openings, whereas the containers have each been provided with hooking edges (10) with upward facing openings. The containers can be stacked. The bottom one of a stack of containers rests upon the bottom of the frame. <IMAGE>
Patent DE-69519998-D1 (DE)
Inventor: VAN DER HEYDEN ERIC
IPC: H01R13/71
Filed: 1995-10-17
Granted: 2001-03-01
Abstract: PCT No. PCT/IB95/00883 Sec. 371 Date Jun. 30, 1997 Sec. 102(e) Date Jun. 30, 1997 PCT Filed Oct. 17, 1995 PCT Pub. No. WO96/13926 PCT Pub. Date May 9, 1996A cradle connector for a radio-telephone base station has a plurality of terminals mounted in insulative housings the terminal interconnected by a shorting bar inmoulded to the housing. The terminals have spring section and contacts that are depressible against action of the spring to allow relatively large tolerances in the positioning of the telephone with respect to the base station. The contacts have extensions that abut against the shorting bar when the connector is disconnected, whereby one of the terminals is connected to ground so that electrostatic discharges do not damage the base station circuitry. Certain extensions can be removed for some of the terminals if such terminals should not be grounded (e.g. power terminals). The shorting bar could be made of wire that interconnects a plurality of housings during manufacturing and handling for reducing the cost thereof. The cradle connector is thus compact, cost-effective and protected against electrostatic discharge.
Patent DE-69526728-D1 (DE)
Inventor: LEONARD JOHN P
IPC: A61P37/00
Filed: 1995-03-07
Granted: 2002-06-20
Abstract: Method of treating autoimmune conditions are disclosed comprising administering to a mammalian subject IL-12 or an IL-12 antagonist. In certain preferred embodiments the autoimmune condition is one which is promoted by an increase in levels of IFN-³ or TNF-±. Suitable conditions for treatment include multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, autoimmune pulmonary inflammation, Guillain-Barre syndrome, autoimmune thyroiditis, insulin dependent diabetes melitis and autoimmune inflammatory eye disease.