baber/WOPTO huggingface dataset:
Patent WO-2020113098-A1 (WO)
Title: Centralized and decentralized individualized medicine platform
Inventor: MAHMOOD KHURRAM
IPC: G06F19/00
Filed: 2019-11-27
Abstract: The subject disclosure relates to systems, devices, and methods for executing operations related to procurement of individualized medicine therapies. Also disclosed are embodiments systems, methods, and devices for accessing a wide range of individualized medicine platform modules. Furthermore, disclosed herein are individualized medicine platform systems, methods and devices communicatively coupled to blockchain computing systems comprising several nodes. The disclosed systems, methods, and devices also generate chain of custody and chain of identity event data.
Patent WO-2020118202-A1 (WO)
Inventor: PATEL HITISHA
IPC: A61K31/015
Filed: 2019-12-06
Abstract: Disclosed herein are methods of treating a drug resistant estrogen receptor alpha¬ positive cancer in a subject having a mutant estrogen receptor alpha, the method comprising administering to the subject a therapeutically effective amount of elacestrant, or a pharmaceutically acceptable salt or solvate thereof, wherein the mutant estrogen receptor alpha comprises one or more mutations selected from the group consisting of D538G, Y537X 1 , L536X 2 , P535H, V534E, S463P, V392I, E380Q and combinations thereof, wherein: Xi is S, N, or C; and X 2  is R or Q. In some embodiments, the drug resistant estrogen receptor alpha-positive cancer is selected from the group consisting of breast cancer, uterine cancer, ovarian cancer, and pituitary cancer.
Patent WO-2020131558-A1 (WO)
Title: Method for led fault detection and mechanism having led fault detection
Inventor: BLANCHARD EDWARD JOHN
IPC: H05B45/52
Filed: 2019-12-12
Abstract: An illumination mechanism includes a plurality of LEDs for illuminating a surface and is configured to determine whether one of the plurality of LEDs has faulted. A pair of LED sets is provided with the sets electrically connected in parallel via terminal connections of each set of LEDs. Regardless of at least one of environmental temperature or minor differences in minimum forward voltages of individual LEDs, the mechanism is configured to discern whether at least a single LED of one set of LEDs of the pair has faulted. In instances where the sets of LEDs are separated from a controller or voltage measurement circuitry, the cost, real estate consumption, and manufacturing complexity associated with additional wiring and connections are minimized.
Patent WO-2020142360-A1 (WO)
Inventor: CHOI BYEONGDOO
IPC: H04N19/36
Filed: 2019-12-27
Abstract: L'invention concerne la reconstruction d'une image courante codée pour un décodage vidéo qui comprend les étapes suivantes consistant à : décoder des informations de partitionnement d'image correspondant à l'image courante ; déterminer si un remplissage est appliqué à des sous-régions de l'image courante à l'aide des informations de partitionnement d'image ; sur la base de la détermination du fait que le remplissage n'est pas appliqué, décoder les sous-régions sans effectuer de remplissage de la pluralité de sous-régions ; sur la base de la détermination du fait que le remplissage est appliqué, déterminer si le remplissage comprend un remplissage enveloppant à l'aide des informations de partitionnement d'image ; sur la base de la détermination du fait que le remplissage ne comprend pas de remplissage enveloppant, appliquer un remplissage de répétition aux sous-régions, et décoder les sous-régions à l'aide du remplissage de répétition ; sur la base de la détermination du fait que le remplissage comprend un remplissage enveloppant, appliquer le remplissage enveloppant aux sous-régions, et décoder les sous-régions à l'aide du remplissage enveloppant ; et reconstruire l'image courante sur la base des sous-régions décodées.
Patent WO-2020140088-A1 (WO)
Title: Anti-pd-1 binding proteins and methods of use thereof
Inventor: JOHNSON DAVID
IPC: C12Q1/6806
Filed: 2019-12-27
Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to PD-l and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
Patent WO-2020150388-A1 (WO)
Title: Appareils, systèmes et procédés pour des mesures de flux de gaz avec des plateformes mobiles
Inventor: KREITINGER AARON
IPC: G01S13/02
Filed: 2020-01-15
Abstract: L'invention concerne des appareils, des systèmes et des procédés pour la spectroscopie laser à trajet ouvert avec des plateformes mobiles. Un système donné à titre d'exemple peut comprendre une première plateforme mobile et une seconde plateforme mobile, chacune d'elles supportant une charge utile. Un faisceau lumineux dirigé d'une charge utile à une autre peut définir un trajet de mesure, qui peut être à une hauteur particulière au-dessus du sol. Les charges utiles peuvent déterminer une concentration de gaz le long du trajet de mesure. Des informations de vent à la hauteur de mesure peuvent être utilisées pour déterminer un flux de gaz. Une plateforme mobile ou les deux plateformes mobiles peuvent ensuite se déplacer vers un nouvel emplacement et prendre une mesure le long d'un nouveau trajet de mesure. En combinant les trajets de mesure, le flux de gaz à travers une surface de flux peut être déterminé.
Patent WO-2020167440-A1 (WO)
Title: Maintenance pour sources de plasma à distance
Inventor: POLAK SCOTT
IPC: H01J37/32
Filed: 2020-01-23
Abstract: L'invention concerne un système et un procédé pour optimiser la maintenance d'une source de plasma à distance consistant à enregistrer des données à partir d'une source de plasma à distance. Les données comprennent des mesures d'une ou plusieurs caractéristiques de fonctionnement de la source de plasma à distance sur une période de temps et une pluralité d'indications d'événement de défaillance de système. Le procédé peut consister à recevoir les données; à analyser les données; et à déterminer, sur la base de corrélations entre les mesures de l'une ou plusieurs caractéristiques de fonctionnement et de la pluralité d'événements de défaillance de système, un seuil d'un point de fonctionnement. Le point de fonctionnement peut comprendre les mesures de l'une ou plusieurs caractéristiques de fonctionnement à un moment particulier. Le seuil signifie qu'un événement de défaut de système en attente est probable à un degré de confiance défini dans une fenêtre de temps spécifiée. Le système fournit une notification pour effectuer une maintenance préventive sur la source de plasma à distance.
Patent WO-2020167472-A1 (WO)
Title: Appareil et procédé de chauffage de conduit comportant une résistance à la corrosion améliorée
Inventor: GOLLER MARTIN HERBERT
IPC: F16L53/70
Filed: 2020-01-29
Abstract: La présente invention concerne un appareil de chauffage de conduit et un procédé de chauffage d'un conduit. L'appareil de chauffage de conduit comprend un élément chauffant annulaire entourant de manière circonférentielle au moins une partie du conduit. L'élément chauffant annulaire comprend un canal annulaire et le procédé comprend l'écoulement d'un fluide de refroidissement à travers celui-ci. L'élément chauffant annulaire comprend également une région d'interface s'étendant entre le canal annulaire et un matériau céramique réfractaire contenu dans une atmosphère. Une température à un niveau d'une limite entre la région d'interface et le matériau céramique réfractaire est au-dessus du point de rosée de l'atmosphère.
Patent WO-2020163501-A1 (WO)
Title: Enhanced smoking product
Inventor: COOPER JEFFREY
IPC: A24D1/02
Filed: 2020-02-05
Abstract: A smoking product using splined leaves, such as cannabis/hemp leaves, orientated and configured to achieves a unique cylindrical/tubular structure wherein the splines (e.g., the veins of a leaf structure) are arranged to achieve a burning chamber that creates a non-laminar airflow resulting in an enhanced burning environment.
Patent WO-2020176224-A1 (WO)
Inventor: SHAH DILIP M
IPC: A01N63/60
Filed: 2020-02-07
Abstract: Antimicrobial nodule specific cysteine rich (NCR2) peptides and proteins are disclosed along with compositions comprising the NCR2 peptides or NCR2 proteins and transgenic or genetically edited plants or microorganisms that express the NCR2 peptides or proteins to inhibit growth of pathogenic microbes. Such NCR2 peptides, proteins, compositions, plants, and microorganisms can provide for inhibition of fungal and oomycete growth.
Patent WO-2020167948-A1 (WO)
Title: Compositions and methods for stem cell therapy
Inventor: SIMPSON RICHARD
IPC: C07C237/04
Filed: 2020-02-12
Abstract: Provided herein are compositions and methods for improving outcome in stem cell transplantation. In particular, provided herein are compositions and methods for improving efficacy and reducing graft versus host disease in allogenic cell transplantation.
Patent WO-2020176573-A1 (WO)
Inventor: CHIRILA FLORIN VALENTIN
IPC: G01N33/483
Filed: 2020-02-26
Abstract: This invention provides methods for diagnosing Alzheimer's disease in a symptomatic human subject. These methods comprise measuring the growth rate, size and/or protein amount of a subject's skin fibroblasts and/or lymphocytes, and determining whether these values differ in certain ways from those of corresponding non-Alzheimer's disease dementia cells. This invention also provides methods for determining whether an asymptomatic human subject is at risk from becoming afflicted with Alzheimer's disease.
Patent WO-2020181211-A1 (WO)
Title: Bone graft delivery system and method for using same
Inventor: MILELLA MICHAEL
IPC: A61B17/70
Filed: 2020-03-06
Abstract: The present invention relates to an apparatus, system and method for delivery of bone graft material in a patient's spine. The graft delivery device according to various embodiments delivers and disperses biologic material to a disc space and without withdrawal from the surgical site. In one embodiment, the graft delivery device includes a plunger with a distal end configured to bend relative to a longitudinal axis as bone graft material is delivery to the disc space. The plunger can include two arms that extend generally parallel to the longitudinal axis. The graft delivery device may selectively deliver a fusion cage for deposit to the same disc space.
Patent WO-2020186188-A1 (WO)
Inventor: RATNAGIRI RAMABHADRA
IPC: C08F222/08
Filed: 2020-03-13
Abstract: Described herein are polyoxymethylene (POM) compositions comprising polyoxymethylene and styrene maleic anhydride (SMA) copolymers or modified SMA copolymers, said POM compositions exhibiting improved physical properties such as heat deflection temperatures compared to POM compositions which do not comprise SMA copolymers.
Patent WO-2020197962-A1 (WO)
Inventor: SCHMUGAR CRAIG
IPC: H04L29/06
Filed: 2020-03-20
Abstract: There is disclosed in one example a computing apparatus, including: a hardware platform including a processor and a memory; a contextual reputation store; and instructions encoded within the memory to provision a security agent configured to: create a user persona in the contextual reputation store based at least in part on the user's interaction with the computing apparatus; compute a persona-weighted reputation for an action and store the persona-weighted reputation action to the contextual reputation store; intercept a user action on the computing apparatus; determine a current user persona; determine from the contextual reputation store a persona-weighted reputation for the user action; and take a security action based at least in part on the persona-weighted reputation for the user action.
Patent WO-2020214899-A1 (WO)
Title: Supplemental enhancement information message for embedded image
Inventor: WANG XIANGLIN
IPC: H04N19/96
Filed: 2020-04-17
Abstract: An electronic apparatus performs a method of encoding a picture into a video bitstream and a method of extracting a picture from an encoded video bitstream, respectively. To encode a picture into a video bitstream, the electronic apparatus determines a set of parameters for the picture, generates an embedded image supplemental enhancement information (SEI) message of the picture using the set of parameters and then adds the embedded image SEI message to metadata of the video bitstream. To extract a picture from an encoded video bitstream, the electronic apparatus identifies, within video metadata of the encoded video bitstream, an embedded image SEI message, extracts a set of parameters from the embedded image SEI message, and generates a picture from image data stored in the embedded image SEI message using the set of parameters.
Patent WO-2020219355-A1 (WO)
Inventor: CURRY ROBERT
IPC: F16K37/00
Filed: 2020-04-17
Abstract: A heated throttle valve apparatus is disclosed herein, which includes a valve system with a valve driver configured to provide a rotational force to a valve assembly via a thermal isolating drive coupler configured to prevent the transfer of thermal energy from the valve assembly to the valve driver. The valve assembly includes a valve body and a valve closure member, a valve shaft with a valve shaft heater in a first heating zone and one or more body heaters in a second heating zone, permitting the user to control temperature in the heating zones independently. An electrical conductor strain relief is provided, configured to eliminate strain in the shaft heater electrical conductors when the valve closure member undergoes a change in angular orientation. The electrical conductor strain relief includes a flexible member with a curvilinear shape wound between a first connection area and a second connection area.
Patent WO-2020223495-A1 (WO)
Inventor: CHEUNG SHIUFUN
IPC: G10L21/0208
Filed: 2020-04-30
Abstract: Systems, methods, and machine-readable storage devices that receive an input signal representing audio captured using a microphone. The input signal includes portions that represent acoustic output from one or more audio sources, and a portion that represents other acoustic energy in the environment. A frequency domain representation of the input signal is iteratively modified to substantially reduce effects due to all but a selected one of the portions, from which an estimate of the power spectral density, PSD, of the selected portion is determined. Based upon the estimated PSD a noise or echo component is reduced, or a replacement noise is provided.The iterative modification involves a diagonalization of the cross-spectral density matrix to remove content coherent with a first audio input from the auto and cross-spectra of other signals.
Patent WO-2020231726-A1 (WO)
Inventor: GRAY NATHANAEL
IPC: A61K38/45
Filed: 2020-05-07
Abstract: Disclosed are compounds that possess inhibitory activity against FAK. Also disclosed are pharmaceutical compositions containing the compounds and methods of using the compounds to treat cancer mediated by aberrant FAK activity.
Patent WO-2020231836-A1 (WO)
Inventor: VENUGOPAL KIRAN
IPC: H04W72/04
Filed: 2020-05-08
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may identify one or more multi-panel capabilities for multi-panel operation of a plurality of panels associated with the UE. The UE may transmit, to a base station (BS), an indication of the one or more multi-panel capabilities. The BS may transmit a scheduling configuration to the UE, which is based on the one or more multi-panel capabilities.
Patent WO-2020236502-A1 (WO)
Inventor: KUMAR VIKRAM S
IPC: A61P35/00
Filed: 2020-05-14
Abstract: The invention provides combination therapies for the treatment of cancer. The combination therapies include a first agent that alters a metabolic pathway and a second agent that targets the metabolic pathway. The combination therapies are useful for treating cancers having tumor cells with different phenotypes, such as cancers of the blood, breast, colon, and prostate.
Patent WO-2020232368-A1 (WO)
Inventor: MEHTA PARINDA
IPC: G01N33/50
Filed: 2020-05-15
Abstract: A method for determining a personalized full dose of a melphalan compound (e.g., melphalan) in a reduced intensity conditioning regimen (RIC) prior to hematopoietic cell transplantation for a subject based on pharmacokinetic features of the melphalan compound administered to the subject at a test dose.
Patent WO-2020236787-A1 (WO)
Inventor: O'BRIEN WILLIAM
IPC: E01H5/09
Filed: 2020-05-19
Abstract: Une souffleuse à neige selon l'invention peut comprendre un cadre de corps, une poignée, un collier et une goulotte. Le cadre de corps peut délimiter une entrée de corps et une sortie de corps. La poignée peut être fixée au cadre de corps. La goulotte peut être fixée au cadre de corps pour diriger la neige à partir de celui-ci.
Patent WO-2020243413-A1 (WO)
Inventor: SUBRAMANIAM VISHWANATH
IPC: G01N27/32
Filed: 2020-05-29
Abstract: Disclosed herein are methods and apparatus for making a determination whether a blood sample is, or is not, infected with a malaria parasite. The determination is made using a trained machine-learning (ML) algorithm. In some aspects, a microfluidic chip is used for the concentration of red blood cells infected with these parasites from uninfected red blood cells, the staining of the blood sample which differentially stains infected and uninfected red blood cells, and holds the sample of interest for imaging. The microfluidic chip is inserted into an optical subsystem that magnifies the image created from transmitted light microscopy. The magnified image is captured with a camera, and a trained ML algorithm assesses if the sample does or does not contain the parasite. Generally, the ML algorithm is executed on a portable computing device such as a smartphone.
Patent WO-2020247938-A1 (WO)
Inventor: NILOSEK DAVID
IPC: G06T7/73
Filed: 2020-06-08
Abstract: Systems and methods are disclosed for using spatial filter to reduce bundle adjustment block size, including a method comprising: assigning a plurality of feature tracks to a voxel corresponding to a region of a geographic area, the voxel having a length, a width and a height, each feature track including a geographic coordinate within the region, a first image identifier identifying a first image, a second image identifier identifying a second image, a first pixel coordinate identifying a first location of a first feature in the first image, and a second pixel coordinate identifying a second location of the first feature within the second image; determining a quality metric value of the feature tracks assigned to the voxel; and conducting bundle adjustment on a subset of the feature tracks assigned to the voxel, the subset of the feature tracks based on the quality metric value.
Patent WO-2020257712-A1 (WO)
Title: Protéines de fusion facteur de stimulation de colonies de granulocytes-macrophages/polypeptide de type élastine et leurs utilisations
Inventor: MACKAY JOHN
IPC: A61K47/64
Filed: 2020-06-19
Abstract: L'invention concerne des protéines de fusion solubles et biologiquement actives comprenant un facteur stimulant les colonies de granulocytes-macrophages (GM-CSF) qui a été fusionné ou lié à un polypeptide capable de subir une séparation de phase réversible dépendant de la température, et leurs utilisations.
Patent WO-2020264354-A1 (WO)
Inventor: SHRINER PAUL
IPC: H04R25/00
Filed: 2020-06-26
Abstract: A system includes a hearing instrument and a case configured to store at least a portion of the hearing instrument. The hearing instrument includes a speaker configured to generate a sound wave, and at least one magnetic component that includes one or more of a coil configured to generate a current in response to detecting an alternating magnetic field, a magnetic shield configured to provide an electromagnetic shield for one or more components of the hearing instrument, a crosspin configured to provide a structural support between two opposing sides of the hearing instrument, a battery, or a charging contact configured to electrically couple the battery to a power source. The case includes a retention magnet configured to generate a static magnetic field that detachably couples at least the portion of the hearing instrument with the case by attracting the magnetic component of the hearing instrument to the case retention magnet.
Patent WO-2021011455-A1 (WO)
Title: Dispositifs et procédés de criblage rapide de médicaments d'abus et d'autres analytes
Inventor: WANG PING
IPC: G01N33/543
Filed: 2020-07-13
Abstract: L'invention concerne des dispositifs, des kits et des procédés de détection rapide d'analytes d'intérêt, tels que des médicaments d'abus, à des concentrations comparativement faibles. La technologie fait appel à des dispositifs d'écoulement latéral de dosage compétitif qui utilisent un complexe nanoparticule-anticorps pour fournir un marqueur visuellement perceptible au contact d'un échantillon ayant un niveau supérieur à un niveau de coupure d'analyte.
Patent WO-2021026260-A1 (WO)
Inventor: SEHSAH OSSAMA
IPC: E21B41/00
Filed: 2020-08-05
Abstract: Systems and methods for delivering a tubular string into a subterranean well include a tubular running machine. The tubular running machine has a machine housing that includes a tubular member with a central bore. A turbine is located within the central bore of the machine housing. A control module is operable to provide energy and a communication signal to the turbine. A downhole connection assembly is located at a downhole end of the machine housing and is operable to releasably secure the tubular running machine to the tubular string.
Patent WO-2021034534-A1 (WO)
Inventor: DAVIDSON MICHAEL
IPC: A61F2/66
Filed: 2020-08-11
Abstract: La présente invention concerne une cheville prothétique à alignement anatomique avec une assistance passive et des procédés associés. La cheville prothétique comprend une astragale accouplée de façon mobile à une section de tibia par un connecteur autour duquel l'astragale peut ainsi être pivotée pendant la locomotion par un utilisateur de la cheville prothétique. L'assistance passive fournit une force de dorsiflexion sélectionnée pour aider les phases de poussée ou de pré-oscillation de la marche pour l'utilisateur.
Patent WO-2021041027-A1 (WO)
Title: An array of capacitors, an array of memory cells, a method of forming an array of capacitors, and a method of forming an array of memory cells
Inventor: TANG SANH
IPC: H01L27/108
Filed: 2020-08-12
Abstract: A method of forming an array of capacitors comprises forming a vertical stack above a substrate. The stack comprises a horizontally- elongated conductive structure and an insulator material directly above the conductive structure. Horizontally- spaced openings are formed in the insulator material to the conductive structure. An upwardly-open container- shaped bottom capacitor electrode is formed in individual of the openings. The bottom capacitor electrode is directly against conductive material of the conductive structure. The conductive structure directly electrically couples the bottom capacitor electrodes together. A capacitor insulator is formed in the openings laterally-inward of the bottom capacitor electrodes. A top capacitor electrode is formed in individual of the openings laterally-inward of the capacitor insulator. The top capacitor electrodes are not directly electrically coupled together. Structure independent of method is disclosed.
Patent WO-2021030486-A1 (WO)
Inventor: HENNIG MARK
IPC: B60C23/00
Filed: 2020-08-12
Abstract: A rotary union for a tire inflation system includes a body having a first end and a second end, the first end comprising threads for threaded coupling to a hubcap, the body forming a fluid channel extending from the first end to a surface of the body; a sleeve rotatably disposed on the body, the sleeve comprising a hose connection port, the sleeve being sealed to the body such that fluid may flow along a sealed path from the fluid channel to the hose connection; and a tubular member having a first end sealingly disposed in the fluid channel at the first end of the body.