Patent SG-11201808598U-A (SG)
Title: Detecting microbial infection in wounds
Inventor: BURNET MICHAEL
IPC: G01N21/78
Filed: 2017-03-30
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD HIM 0 11101 0I0 11111 Mt 0M011110111101 HO MI 11110 1111 OM Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\"1 WO 2017/168249 A3 05 October 2017 (05.10.2017) WIPO I PCT (51) International Patent Classification: gor-mendel-strasse 33, Vienna, 1180 (AT). ACIB GMBH G01N 33/52 (2006.01) G01N 33/68 (2006.01) [AT/AT]; Petersgasse 14, Graz, 8010 (AT). GO1N 21/78 (2006.01) (72) Inventors: BURNET, Michael; Eckener Strasse 18, (21) International Application Number: 72070 Tubingen (DE). HEINZLE, Andrea; Am Hang PCT/IB2017/000442 4, Gratwein-strassengel, 8111 (AT). SIGL, Eva; Veitsch- (22) International Filing Date: er Strasse 44, Sankt Barbara Im Murztal, 8664 (AT). 30 March 2017 (30.03.2017) LUSCHNIG, Daniel; Marburger Strabe 2, Graz, 8042 (AT). GAMERICH, Clemens; Schumanngasse 24, Graz, (25) Filing Language: English 8010 (AT). TEGL, Gregor; Karlsgasse 2-6/9, Tulln, 3430 (26) Publication Language: English (AT). Graz, GUEBITZ, Geoeg; Hans-klopfergasse 21, Hart Bei 8047 (AT). (30) Priority Data: (81) Designated States (unless otherwise indicated, for every 62/315,556 30 March 2016 (30.03.2016) US kind of national protection available): AE, AG, AL, AM, 62/315,546 30 March 2016 (30.03.2016) US AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (71) Applicants: QUALIZYME DIAGNOSTICS GMBH & CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, CO KG [AT/AT]; Neue Stiftingtalstrasse 2, Graz, 8010 DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (AT). UNIVERSITY OF NATURAL RESOURCES HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, AND LIFE SCIENCES, VIENNA [AT/AT]; Gre- KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, (54) Title: DETECTING MICROBIAL INFECTION IN WOUNDS FIG. 7 9 C1* P 13 = H3C011 —, ,,,, , ..„ . H3C.O . ' l\"'' 06H3 OCH3 + + r1 .. St., C 6 chr: 1.6 , 304 GPIIVIS 0,3M T ZST -MO WO '24*1 .2 teituiost 50/ $4>$1 IC n4n at NT 5 ettn at OffC MO wathnd 1 1 1 M White White Blue Yellow Yellow Blue 01 71' N (57) : The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected GA wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The dis- 1-1 closed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/ ---- or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. Additional disclosure IN relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, C::::) and ei follow-up patients suffering from chronic or infected wounds. C [Continued on next page] WO 2017/168249 A3 MIDEDIMOMOIDEIROIDEMOMMEMEIMEMODEfin PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (88) Date of publication of the international search report: 16 November 2017 (16.11.2017)