baber/WOPTO huggingface dataset:
Patent WO-2021150871-A1 (WO)
Title: Compositions and methods for treating neurodegenerative disorders with ripk1/ripk3 inhibitors
Inventor: KHANNA MAY
IPC: A61K31/44
Filed: 2021-01-22
Abstract: This invention relates generally to neurodegenerative diseases and conditions (e.g., Alzheimer's disease) characterized with aberrant RIPK1/RIPK3 binding, RIPK3/MLKL binding, necrosome formation, and/or necroptosis activation. This invention further relates to methods and compositions for treating such neurodegenerative diseases and conditions with pharmaceutical compositions comprising agents capable of inhibiting RIPK1/RIPK3 binding and/or RIPK3/MLKL binding.
Patent WO-2021154707-A1 (WO)
Title: Signaling of beam correlation across millimeter wave frequency bands
Inventor: RAGHAVAN VASANTHAN
IPC: H04B7/04
Filed: 2021-01-26
Abstract: Methods, systems, and devices for wireless communications are described. A first wireless device may receive, from a second wireless device, a carrier aggregation configuration including two millimeter wave frequency bands for communications. The first wireless device may determine a beam correlation parameter based on the carrier aggregation configuration. The first wireless device may determine beams, based on the beam correlation parameter, in the two frequency bands. The first wireless device and the second wireless device may communicate in carrier aggregation using a beam on a first frequency band and a second beam on a second frequency band.
Patent WO-2021155167-A1 (WO)
Title: Bile acid-gcpii inhibitor conjugates to treat inflammatory diseases
Inventor: SLUSHER BARBARA
IPC: C07J41/00
Filed: 2021-01-29
Abstract: GCPII inhibitors comprising 2-(phosphonomethyl) pentanedioic acid (2-PMPA) conjugated to a bile acid and their use for treating a disease or condition associated with elevated levels of GCPII, including inflammatory bowel disease.
Patent WO-2021158750-A1 (WO)
Inventor: MARTY MICHAEL
IPC: H01J49/24
Filed: 2021-02-04
Abstract: L'invention concerne un système automatisé de spectrométrie de masse à échange lipidique, par exemple, mesurant l'affinité d'une protéine membranaire pour des lipides. Les systèmes automatisés selon la présente invention permettent de mesurer la spécificité d'interactions protéines membranaires-lipides, de détecter un remodelage de l'environnement membranaire, et de déterminer une composition lipidique optimale pour des protéines membranaires.
Patent WO-2021158914-A1 (WO)
Title: Digital display system and method
Inventor: COHEN ALON
IPC: A63B71/06
Filed: 2021-02-05
Abstract: A system for controlling a clock device is provided. The system includes a clock device in communication with a remote computing device. The remote device is configured to adjust the time of a countdown and define an adjusted time value. The remote device communicates the adjusted time to the clock device, which automatically displays the adjusted time on a screen. The adjusted time is further communicated to a cloud server via API. The adjusted time is accessible by authorized third parties for display or broadcast. Accordingly, a user may adjust and track a countdown and may define an official time that is automatically displayed to a variety of end-users in real-time. The clock device may be positioned adjacent a competition area and may include a rigid metal frame and a flexible LED screen extending around the perimeter of the frame. The clock device may include hardware and software for processing and outputting the adjusted time to the cloud server.
Patent WO-2021194720-A1 (WO)
Title: Colliers à coins pouvant manipuler des éléments de puits de tailles multiples
Inventor: AMEZAGA FEDERICO
IPC: E21B19/24
Filed: 2021-03-04
Abstract: La présente invention concerne un collier à coins pour manipuler/saisir des composants de puits de différentes tailles pouvant comprendre de multiples ensembles de glissement répartis de manière circonférentielle autour d'un axe central, chaque ensemble de glissement comprenant un support de glissement pouvant être déplacé radialement par rapport à l'axe central, un glissement pouvant être déplacé par rapport au support de glissement, et un actionneur de glissement pouvant être actionné pour déplacer le glissement par rapport au support de glissement, l'actionneur de glissement étant disposé au moins partiellement à l'intérieur du support de glissement. Chaque ensemble de glissement peut comprendre un actionneur de support de glissement qui déplace radialement le support de glissement. Un ensemble table peut être monté sur un appareil de sondage, une surface supérieure de l'ensemble table affleurant un plancher de forage de l'appareil de sondage. Un autre collier à coins peut comprendre un ensemble de guidage de tuyaux doté de multiples guides et d'actionneurs de guidage. Chaque actionneur de guidage fait tourner un des guides de tuyau respectifs autour d'un axe de guidage respectif qui est parallèle à l'axe central.
Patent WO-2021178759-A1 (WO)
Inventor: ROCK KAILEIGH E
IPC: A61N1/372
Filed: 2021-03-05
Abstract: An implantable medical device (IMD) comprises a plurality of deep tines configured to be advanced into a septum of a heart of a patient in different directions that are not parallel to a longitudinal axis of the implantable medical device, wherein each deep tine of the plurality of deep tines is configured to deliver cardiac pacing to cardiac tissue distal to a chamber of the heart in which the IMD is implanted, and one or more shallow electrodes engageable with the septum, wherein the one or more shallow electrodes are configured to deliver cardiac pacing to the chamber of the heart in which the IMD is implanted.
Patent WO-2021211721-A1 (WO)
Title: Accountability tracking system
Inventor: BYRD JEREMY
IPC: G06Q10/00
Filed: 2021-04-14
Abstract: A system and application for maintaining and tracking accountability by users. The system allows a user to create and assign one or more tasks, actions, or objectives to one or more other users, receive information or confirmation from said one or more other users of a status or completion of a particular task, action, or objective, and respond thereto, if necessary. In several embodiments, two or more users may jointly send and/or receive information or confirmation about the status or completion of a particular task, action or objective, thereby providing accountability among the group of users. The particular task, action or objective may be assigned, performed or accomplished by a single individual, by members of a group individually, and/or by members of group together.
Patent WO-2021231107-A1 (WO)
Title: Opa1 antisense oligomers for treatment of conditions and diseases
Inventor: AZNAREZ ISABEL
IPC: C12N15/113
Filed: 2021-04-30
Abstract: Alternative splicing events in genes can lead to non-productive mRNA transcripts which in turn can lead to aberrant protein expression, and therapeutic agents which can target the alternative splicing events in genes can modulate the expression level of functional proteins in patients and/or inhibit aberrant protein expression. Such therapeutic agents can be used to treat a condition or disease caused by protein deficiency and/or mitochondrial function deficit.
Patent WO-2021231746-A1 (WO)
Title: High performance acoustic door
Inventor: HIBBS DANIEL L
IPC: E06B3/82
Filed: 2021-05-13
Abstract: An acoustic door assembly having 1-3/4" thickness, a sound transmission class (STC) rating greater than 50, UL10C 20-minute fire rating, and constructed without sheet metal or lead. In an embodiment, the door assembly includes a frame housing a decoupled internal core sandwiched between two mass-loaded vinyl outer faces. The internal core includes a multi-layering of low-density layers for absorbing high-frequency noise, damping layers of mass-loaded vinyl for absorbing low-frequency noise, and a flame-retardant layer. The outer faces are a multi-layered assembly coupled to a frame of the door assembly and in contact communication to the internal core, the outer faces having layers of mass-loaded vinyl, plywood, high-density fiberboard, and a veneer.
Patent WO-2021236652-A1 (WO)
Inventor: KALMAN ROBERT
IPC: G02B6/12
Filed: 2021-05-18
Abstract: Selon l'invention, une microDEL peut être utilisée pour générer de la lumière pour des communications intra-puces ou inter-puces. La microDEL, ou une couche active de la microDEL, peut être incorporée dans un guide d'ondes. Le guide d'ondes peut comprendre une lentille.
Patent WO-2021236971-A1 (WO)
Inventor: WANG CHAO
IPC: C07D209/08
Filed: 2021-05-20
Abstract: L'invention concerne un catalyseur solide hautement actif et sélectif comprenant de l'iridium (Ir) monoatomique stable ancré dans une zéolithe, par exemple ZSM-5, pour un recyclage valorisant de matières plastiques, telles qu'un polyéthylène haute densité, pour produire des produits hydrocarbonés de faible masse moléculaire de valeur.
Patent WO-2021236980-A1 (WO)
Title: Coronavirus antigen compositions and their uses
Inventor: ECHELARD YANN PAUL GUY
IPC: A61K39/145
Filed: 2021-05-20
Abstract: The disclosure provides compositions and methods comprising circular polyribonucleotides comprising a sequence encoding a coronavirus antigen, and compositions and methods comprising linear polyribonucleotides comprising a sequence encoding a coronavirus antigen. Compositions and methods are provided that are related to generating polyclonal antibodies, for example, using the disclosed circular polyribonucleotides or the disclosed linear polyribonucleotides.
Patent WO-2021247264-A1 (WO)
Inventor: KRISHNAN MADHU PERINGASSERY
IPC: H04N19/124
Filed: 2021-05-24
Abstract: A method, computer program, and computer system for video coding is provided. Video data including one or more quantized coefficients is received. One or more index values associated with the quantized coefficients are mapped to one or more step values based on an exponential mapping. The video data is decoded based on the one or more step values.
Patent WO-2021252925-A1 (WO)
Title: Cooperative lidar object detection via feature sharing in deep networks
Inventor: MARVASTI EHSAN
IPC: G01C3/00
Filed: 2021-06-11
Abstract: Situational awareness as a necessity in connected and autonomous vehicles domain is a subject of significant research in recent years. The driver's safety is directly dependent on robustness, reliability and scalability of such systems. Cooperative mechanisms have provided a solution to improve situational awareness by utilizing communication networks. These mechanisms mitigate problems such as occlusion and sensor range limitation. However, the network capacity is a factor determining the maximum amount of information being shared among cooperative entities. A focus of this work is to reduce the network capacity requirements while maintaining the desirable object detection performance by utilizing and modifying the concept of feature sharing. Described here is a mechanism to further improve object detection performance by utilizing novel decentralized parallel frameworks and anew shared data alignment method to allow parallel and cooperative processing of sensed data in multiple locations yielding significant improvements in object detection.
Patent WO-2021257952-A1 (WO)
Inventor: ESTES MARK C
IPC: A61M5/172
Filed: 2021-06-18
Abstract: L'invention concerne des modes de réalisation de systèmes et de procédés d'administration d'un médicament à l'aide d'une pompe. Les procédés comprennent l'insertion d'une première canule dans un tissu sous-cutané. Un médicament est administré à partir d'une pompe à médicament au moyen de la première canule selon un protocole de dosage. La première canule peut être retirée après une période et une seconde canule peut être insérée. Le procédé comprend la modification du protocole de dosage sur la base d'un indicateur de changement de canule, la modification comprenant la réalisation de calculs de réseau neuronal à l'aide de données d'erreur calculées précédemment, conduisant à un protocole de dosage modifié. Le médicament est administré à partir de la pompe à médicament au moyen de la seconde canule selon le protocole de dosage modifié.
Patent WO-2021257953-A1 (WO)
Title: Compositions probiotiques prêtes à l'emploi et leurs utilisations
Inventor: ROBB EDWARD
IPC: A61K35/747
Filed: 2021-06-18
Abstract: L'invention concerne des compositions probiotiques appropriées pour une administration intravaginale à un animal non humain comprenant une ou plusieurs souches de bactéries natives au vagin de l'espèce animale et une base non aqueuse, des produits probiotiques, des kits et des systèmes comprenant les compositions probiotiques, et des procédés d'utilisation des compositions probiotiques, des produits, des kits et des systèmes.
Patent WO-2022006037-A1 (WO)
Title: System and method for water treatment with venturi plasma discharge
Inventor: CHO DANIEL J
IPC: C02F1/78
Filed: 2021-06-29
Abstract: A water treatment system includes a venturi injector including a venturi inlet that intakes water to be treated, a venturi throat including an orifice in fluid communication with a gas source, a discharge electrode integrated into a gas inlet in fluid communication with the orifice for generating a plasma discharge, thereby producing treated water, and a venturi outlet that discharges the treated water.
Patent WO-2022051022-A1 (WO)
Title: Co-lyophilized rna and nanostructured lipid carrier
Inventor: KRAMER RYAN M
IPC: A61K9/19
Filed: 2021-07-02
Abstract: This disclosure provides thermostable, lyophilized compositions of nanostructured lipid carrier (NLC) particles, methods of making the compositions, and methods of using the compositions for stimulating an immune response. The lyophilized compositions are in the form of cakes that form oil-in-water emulsions upon reconstitution. The compositions comprise NLC particles lyophilized in the presence of a cake-forming excipient. The compositions may be lyophilized with a bioactive agent, or the bioactive agent may be added after reconstitution. The bioactive agent may be RNA that encodes an antigen such as a viral protein. The thermostable, lyophilized compositions have uses as vaccine platforms or vaccines. The lyophilized cake maintains shape, structure, and color for at least 21 months stored at room temperature. Integrity and activity of the bioactive agent is maintained for at least eight months at room temperature and at least 21 months refrigerated.
Patent WO-2022016132-A1 (WO)
Title: Intraocular lenses with shape-changing optics
Inventor: ELLIS FORREST J
IPC: A61F2/16
Filed: 2021-07-17
Abstract: An intraocular lens (IOL) with a shape-changing optic is provided. The IOL includes an anterior face and/or a posterior face that is fabricated from a poly(dimethylsiloxane) elastomer having a durometer between about 30 Shore A to about 50 Shore A. A chamber is located between the anterior face and the posterior face and includes a silicone oil including diphenyl siloxane and dimethyl siloxane units. The silicone oil has a maximum viscosity of about 700 mm2/s at 25°C and has a mean molecular weight of less than about 3,000 Daltons. An IOL is also provided that includes an anterior face and/or posterior face that is fabricated from a polysiloxane that is at least 99% poly(dimethylsiloxane) elastomer.
Patent WO-2022036104-A1 (WO)
Inventor: SEBAG JULIEN A
IPC: A61K31/4433
Filed: 2021-08-12
Abstract: Compositions and methods for insulin sensitization are provided.
Patent WO-2022060537-A1 (WO)
Title: An autonomous microfluidic device for sample preparation
Inventor: HAUSER JANOSCH
IPC: H01J37/252
Filed: 2021-08-23
Abstract: The method is for preparing a sample in a microfluidic device. The microfluidic device is provided that has a first reservoir in fluid communication with a second reservoir in fluid communication with and adjacent to a draining unit that has a first absorbing member disposed therein. The first reservoir contains a first liquid that is held in the first reservoir by a capillary stop valve connecting the first and second reservoirs. The second reservoir has a sample support disposed therein. A second liquid, containing substances, is added to the second reservoir. The second liquid contacts the first liquid and the first absorbing member. The first absorbing member absorbs the second liquid and the first liquid. The substances adhere to the sample support.
Patent WO-2022051172-A1 (WO)
Title: Telephone based tele-health apparatus
Inventor: JUNNARKAR SACHIN S
IPC: A61B7/04
Filed: 2021-08-27
Abstract: A tele-health apparatus includes a telephone having a microphone, an auscultation piece to acquire sounds, and a solid medium acoustically coupling the auscultation piece to the microphone. The auscultation piece is part of a stethoscope, and the solid medium is a windpipe of the stethoscope. The tele-health apparatus also includes an otoscope operable to be disposed in front of a camera of the telephone. A clip holds the stethoscope and the otoscope, and is fixed to the phone. Software modules installed in the telephone enable the tele-health apparatus to engage a user in a two-way audio and/or video consultation with a physician at a remote device in real-time.
Patent WO-2022047094-A1 (WO)
Inventor: GANGI STEVE
IPC: F24S25/00
Filed: 2021-08-27
Abstract: A system for installing a solar panel may include an end of arm assembly tool and a linear guide assembly coupled to the end of arm assembly tool. The end of arm assembly tool includes a frame and plurality of attachment devices, such as suction cups, coupled to the frame. The linear guide assembly includes a linearly moveable clamping tool including an engagement member configured to engage a clamp assembly slidably coupled to an installation structure, and a force torque transducer configured to move the clamping tool along the installation structure. A controller configured to control the force torque transducer and the plurality of attachment devices. The end of arm assembly tool is coupled to a robotic arm and is part of an assembly robot that includes autonomous and non-autonomous vehicles. The various components can be operated by a control system based on operation instructions received from a neural network.
Patent WO-2022076167-A1 (WO)
Inventor: JAKAB LORAND
IPC: H04L12/911
Filed: 2021-09-22
Abstract: Sont divulguées des techniques de suivi de la capacité de calcul d'une plateforme de service d'application extensible en vue d'effectuer une attribution de bande passante dynamique pour des flux de données associés à des applications hébergées par la plateforme de service. Certaines des techniques peuvent consister à attribuer une première quantité de bande passante d'une sous-couche physique d'un réseau pour des flux de données associés à une application. Les techniques peuvent également consister à recevoir, à partir d'un service d'application extensible hébergeant l'application, une indication d'une quantité de ressources informatiques du service d'application extensible qui sont attribuées dans le but d'héberger l'application. Sur la base, au moins en partie, des indications, une seconde quantité de bande passante de la sous-couche physique à attribuer pour les flux de données peut être déterminée. Les techniques peuvent également consister à attribuer la seconde quantité de bande passante de la sous-couche physique du réseau pour les flux de données associés à l'application.
Patent WO-2022159150-A1 (WO)
Inventor: SALGIA RAVI
IPC: A61K31/203
Filed: 2021-09-23
Abstract: La présente invention concerne une méthode de traitement d'un sujet souffrant de cancer, comprenant l'administration au sujet d'une quantité efficace d'un inhibiteur de PP2A et éventuellement d'un ou de plusieurs agents anticancéreux.
Patent WO-2022072358-A1 (WO)
Title: Assembly monitoring system
Inventor: DANZIGER ERIC
IPC: G06K9/62
Filed: 2021-09-28
Abstract: A system and method for receiving, using one or more processors, image data, the image data including a first training video representing performance of one or more steps on a first workpiece; applying, using the one or more processors, a first set of labels to the first training video based on user input; performing, using the one or more processors, extraction on the image data, thereby generating extracted information, the extracted information including first extracted image information associated with the first training video; and training, using the one or more processors, a process monitoring algorithm based on the extracted information and the first set of labels.
Patent WO-2022115194-A1 (WO)
Inventor: DUDUKOVIC NIKOLA
IPC: B22F10/25
Filed: 2021-10-27
Abstract: La présente divulgation concerne un système de fabrication additive. Le système comprend une buse en communication avec une quantité de matériau de charge d'alimentation comprenant des particules de poudre métallique granulaire. La buse est configurée pour déposer les particules de poudre métallique granulaires sur une plaque de construction et/ou une couche de matériau formée précédemment, pour former au moins une couche d'une pièce. Le système comprend également un sous-système générateur de champ magnétique pour produire un champ magnétique configuré pour orienter les particules de poudre métallique granulaires dans une orientation souhaitée avant de faire fondre les particules de poudre métallique granulaire.
Patent WO-2022132420-A1 (WO)
Inventor: BOMONT CATHERINE
IPC: A23J1/14
Filed: 2021-11-29
Abstract: La technologie selon la présente invention divulgue des émulsifiants à base de protéine de pois contenant une protéine de pois dissoute et des émulsions huile-dans-eau contenant l'émulsifiant à base de protéine de pois et présentant ainsi une teneur en protéine de pois dissoute. Les émulsifiants à base de protéine de pois peuvent être fabriqués à partir d'une protéine restant dissoute dans l'eau de traitement d'un procédé d'isolement de protéine de pois. Les émulsifiants à base de protéine de pois dissoute selon l'invention confèrent aux émulsions une bonne stabilité vis-à-vis de la séparation de l'huile.
Patent WO-2022125346-A1 (WO)
Inventor: ROZENTALS EDGARS
IPC: A61J7/04
Filed: 2021-12-01
Abstract: Un distributeur peut comprendre : une entrée de source d'eau de source d'eau facultative; une pluralité de cartouches de compléments comprenant une composition de compléments; au moins un distributeur raccordé de manière fluidique à l'entrée de source d'eau facultative et à la pluralité de cartouches de compléments; un mécanisme de préparation fonctionnellement raccordé à l'entrée de source d'eau facultative et aux cartouches de compléments, le mécanisme de préparation étant configuré pour réguler l'écoulement de fluide à partir de l'entrée de source d'eau facultative et des cartouches de compléments vers le distributeur; un dispositif d'entrée configuré pour recevoir une entrée d'un utilisateur; et un dispositif de commande de distributeur. Le dispositif de commande de distributeur peut être configuré pour : recevoir des informations d'identification d'un utilisateur par l'intermédiaire du dispositif d'entrée; obtenir une préparation posologique complémentaire pour l'utilisateur sur la base d'un protocole de compléments personnalisé; et commander la distribution de l'eau et d'une ou de plusieurs composition(s) de compléments pour fournir la préparation posologique de compléments à l'utilisateur.