baber/WOPTO huggingface dataset:
Patent PT-769942-E (PT)
Inventor: HAENSLER JEAN
IPC: A61P43/00
Filed: 1996-04-11
Abstract: Cationic amphipathic cpds of formula (I) for use as a medicament, are new. A = a single bond, NHR', or NHCOR'; R' = 1-22C opt. substd., opt. unsatd. aliphatic group which is opt. interrupted by O, N, and/or S, and/or by one or more carbocyclic or heterocyclic, opt. unsatd. or aromatic, gps.; R1, R2, R3 = higher alkyl or acyl; R7, R8, R9 = (CH2)n; n = 1-6; R4, R5, R6 = H or opt. substd. 1-22C alkyl, alkenyl, alkynyl, or acyl, all opt. interrupted by O, N, and/or S, or by one or more carbocyclic or heterocyclic, satd, unsatd, or aromatic groups; or at least two of R4, R5 and R6 together with the attached N atom may form quinuclidino, piperidino, pyrrolidino, or morpholino; and X = a non-toxic anion, esp. bromide. Also claimed are: (1) compsns in which (I) is associated with a neutral lipid, esp. di-oleoyl phosphatidyl ethanolamine, in the molar ratio 1:9 - 9:1, optionally as aqueous or lyophilised liposomes; and (2) a method of transfecting eucaryote cells by mixing a transfection agent with at least one plasmid or polynucleotide and contacting with the cells to be transfected.
Patent PT-842660-E (PT)
Inventor: SHU CHENG JUN
IPC: A61P17/00
Filed: 1997-11-18
Abstract: The invention describes a pharmaceutical composition containing a tea (Camellia sinensis) extract containing catechins (more particularly (-)-epigallocatechin gallate) in the form of a 2-20% by weight ointment or a 50-500 mg tea catechin suppository and its use in the treatment of condyloma acuminata (genital warts) caused by human papilloma virus.
Patent PT-912495-E (PT)
Inventor: CAIN-JANICKI KIMBERLY J
IPC: C07C229/34
Filed: 1997-07-10
Abstract: The invention herein is directed to a process for the preparation of ethyl 3S-amino-4-pentynoate which involves treating 3-(trimethylsilyl)-2-propynal with L-phenylglycinol in toluene to produce  alpha S-[[3-(trimethylsilyl)-2-propynylidene amino]benzenethanol; reacting  alpha S-[[3-(trimethylsilyl)-2-propynylidene]amino]benzenethanol with BrZnCH2CO2t-Bu in THF/NMP to produce 1,1-dimethylethyl 3S-[(2-hydroxy-1S-phenylethyl)amino]-5-(trimethylsilyl)-4-pentynoate; reacting the 1,1-dimethylethyl 3S-[(2-hydroxy-1S-phenylethyl)amino]-5-(trimethylsilyl)-4-pentynoate with sodium periodate to form 1,1-dimethylethyl 3S-[(phenylmethylene)amino]-5-(trimethylsilyl)-4-pentynoate; hydrolyzing 1,1-dimethylethyl 3S-[(phenylmethylene)amino]-5-(trimethylsilyl)-4-pentynoate to produce 1,1-dimethylethyl 3S-amino-5-(trimethylsilyl)-4-pentynoate; transesterifying 1,1-dimethyl 3S-amino-5-(trimethylsilyl)-4-pentynoate and desilylating to produce ethyl 3S-amino-4-pentynoate.
Patent PT-1010167-E (PT)
Inventor: KIRJAVAINEN KARI
IPC: E04B1/98
Filed: 1997-10-03
Abstract: The invention relates to a method of and an arrangement for damping a wall movement. In the invention, the strength of an electric field between a surface of a wall and an air-permeable mass plate parallel with the surface is controlled to provide a force opposite to the wall-moving force. A sound wave, for instance, may cause a force moving a wall back and forth, which force is cancelled by the opposite force by means of the method and arrangement of the invention, whereby the movement applied to the wall by the sound wave can be stopped.
Patent PT-944650-E (PT)
Inventor: SANTORO SAMEUL A
IPC: A61K38/10
Filed: 1997-12-10
Abstract: Novel short peptides are disclosed which are selected from the group consisting of TAVTQTYGGNSNGEP and fragments thereof containing the minimal sequence TATQTY. These peptides are antithrombotic agents and mediate divalent cation-independent adhesion of platelets to fibronectin.
Patent PT-973546-E (PT)
Inventor: SANYAL GAUTUM
IPC: A61K39/12
Filed: 1998-04-07
Abstract: Human papillomavirus (HPV) antigen formulations are disclosed which prevent protein aggregation and show prolonged stability as aqueous solutions. These formulations comprise a salt (such as sodium chloride) and a non ionic surfactant (Polysorbate 80 such as Tween 803) in physiologically acceptable concentrations.
Patent PT-1034058-E (PT)
Inventor: WYATT-MAIR GAVIN F
IPC: B22D11/06
Filed: 1998-11-20
Abstract: Method and device for cooling belts of single or twin belt casters. The belt is cooled by a liquid which is contacted with the inner surface of the belt by a system of feed tubes and collection tubes. Liquid is passed out the feed tube, into a channel that communicates with the inner surface of the heated belt, the belt is cooled, and the liquid is removed through collection tubes with a vacuum assist.
Patent PT-976899-E (PT)
Inventor: BOSMAN BAREND
IPC: E05B63/20
Filed: 1999-06-14
Abstract: An automatic inactive door lock (10) for the inactive door of a pair of doors, the active door of which is fitted with an automatic anti-panic lock (2) comprising a latch bolt and a deadbolt is described. The inactive door lock (10) comprises a housing (8); a first bolt (144) arranged within the housing (8) to drive the latch bolt of the anti-panic lock (2); a second bolt (146) arranged within the housing (8) to drive the deadbolt of the anti-panic lock (2); means (88) arranged within the housing (8) attachable to an upper rod (90) to drive the upper rod (90) between a first, normal or locking, position in which the rod (90) extends from the top face of the inactive door and a second, unlocking position in which the rod (90) is within the inactive door; the upper rod (90) being driveable from the first position to the second position on closing of the inactive door; means (96) arranged within the housing (8) attachable to a lower rod (98) to drive the lower rod (98) between a first, normal or locking, position in which the rod (98) extends from the lower face of the inactive door and a second, unlocking position in which the rod (98) is within the inactive door; operating means arranged within the housing (8) operable by an operator to unlock the door by retracting the upper and lower rods (90,98) retaining means (124,38) arranged to hold the lower rod (98) in the retracted position within the door when the operating means is released by the operator and retaining means (114) arranged to hold the upper rod (90) in the extended position when the inactive door is open and the operating means is released by the operator. The retaining means (114) arranged to hold the upper rod (90) in the extended position when the inactive door is open is located within the housing (8). <IMAGE>
Patent IE-790023-L (IE)
Title: Liquid detergent composition
IPC: C11D1/72
Filed: 1979-01-05
Abstract: A stable, non-gelling, low-foaming unbuilt aqueous liquid detergent is obtained by inclusion, in an aqueous medium, of 25-45% of a ternary nonionic detergent mixture, wherein the nonionics are high-, medium- and low-ethoxylated fatty alcohols with specific alkyl chain lengths.
Patent IE-40564-L (IE)
Title: Controlling lubrication
IPC: F16N7/34
Filed: 1975-01-07
Abstract: 1499131 Lubricating W GRUTTER 2 Jan 1975 [8 Jan 1974] 9/75 Heading F2A [Also in Division B1] An airline lubricator comprises a lubricant container 1 through which passes an air flow pipe 2 having a restriction the pressure drop across which is used to pressurize the lubicant supply, there being adjustable control valves in both air and lubircant flows. As shown the restriction is a restricted passage or venturi 5, the upstream side of which is connected to the space over the lubricant bypipe 6, passages 9, 22, 32, valve 30, 31, and passages 26, 33, 23, 12. The lubricant is thus forced up pipe 8 and through passages 10, 25, valve 14, 24 and pipe 7 to the downstream side of the restriction where it is atomized. The valves 30, 31 and 14, 24 are adjustable by means of knob 28 and lever 18 respectively. In another embodiment; see Figs. 2-8 (not shown) the restriction is an aperture (5a) between the air supply pipe (2a) and a delivery pipe (2b) branched off it, and the adjustable valve in the air supply is an adjustable pressure relief valve.
[GB1499131A]
Patent IE-810124-L (IE)
Title: Anti-acne compositions
IPC: C07D249/08
Filed: 1981-01-23
Abstract: Novel compositions for the topical treatment of acne vulgaris comprise a pharmaceutically acceptable amount of benzoylperoxide and an anti-microbially effective amount of an azole derivative of the formula <IMAGE>
[GB2068228A]
Patent IE-870217-L (IE)
Title: Benzothiophene derivatives
IPC: A61K31/44
Filed: 1987-01-28
Abstract: Compounds of formula (I): (wherein n is 0 or 1, R<1> and R<2> are hydrogen or alkyl, one of A<1> and A<2> is - Z-Y and the other is-W-COOH, where W and Z are alkenylene or alkylene and Y is imidazolyl or pyridyl, and the broken lines represent two single bonds or one single bond and one double bond) and their salts, esters and amides have the ability to inhibit the synthesis of thromboxane A2 and hence are useful in the treatment or prophylaxis of thrombotic conditions. They may be prepared by introducing an imidazolyl or pyridyl group into the corresponding compound in which Y is replaced by an active group or atom.
Patent IE-32654-L (IE)
Title: Particle or fibre board
IPC: C08L91/08
Filed: 1969-02-25
Abstract: Gaseous reactive or polymerizable compounds and a gaseous catalyst are incorporated into lignocellulosic particles or fibers, and the compounds are reacted or polymerized in the presence of the catalyst to form a binder during hot pressing of the particles or fibers to form a board.
[US3699202A]
Patent IE-830542-L (IE)
Title: Dibenzazepine derivatives.
IPC: C07D223/20
Filed: 1983-03-14
Abstract: A pharmacologically active compound has the general formulain which R is a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms; R, and R<sub>2</sub>, which can be different, represent a hydrogen atom, a hydroxyl group, an alkyl group, an alkoxy group, an arylalkyl group, or an arylalkoxy group, or can jointly represent an oxygen atom or a CHCOOR,' group where R<sub>1</sub>' is a hydrogen atom or an alkyl group; and R<sub>3</sub> represents a hydrogen or halogen atom or an alkyl, NH<sub>2</sub>, NO<sub>2</sub>, NHCO-alkyl, NHCO-aryl, NHCONH-alkyl or NHCONH-aryl group.These compounds act on the central nervous system and have an anti-convulsant sedative activity.
Patent IE-36494-L (IE)
Title: Closure cap for aerosol container
IPC: B65D39/04
Filed: 1972-05-25
Abstract: 1362244 Tamper-proof closures MARDON ILLINGWORTH Ltd 24 May 1972 [4 June 1971] 18934/71 Heading B8T A tamper-proof cap 20 for an aerosol container 10 is made of resilient synthetic resin and comprises a flared lower edge 25 which engages under a bead 12 on the container 10 and a skirt 28 having a rib 24 which engages under the bead 12, the skirt being frangible over a circumferential portion to form a tear-strip. When the tear strip has been removed, the cap 20 resiliently engages the bead 12 to continue to protect the aersol valve (not shown). The skirt has a groove 26 (or may have circumferential perforations) or the groove may be adjacent the cap wall 22 or the rib 24. The bead 12 may be located at the edge 14 of the container 10.
[GB1362244A]
Patent IE-880893-L (IE)
Title: 4-£4-£4-£4-££2-(2,4-Difluorophenyl)-2-(1H-azolylmethyl)-1,3-¹dioxolan-4-yl|methoxy|phenyl|-1-piperazinyl|phenyl|triazolon¹es
IPC: C07D249/12
Filed: 1988-03-24
Abstract: Novel 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4 -yl] methoxy]phenyl]-1-piperazinyl]phenyl]triazolones of formula <CHEM> wherein Q is N or CH; R is hydrogen, C1-6alkyl or arylC1-6alkyl; and R<1> is hydrogen, C1-6alkyl or arylC1-6alkyl; wherein aryl is phenyl optionally substituted with up to 3 substituents each independently selected from halo, C1-6alkyl, C1-6alkyloxy and trifluoromethyl, the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are anti-microbial agents; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent FI-853202-L (FI)
Inventor: PIHLAJAMAA PAAVO KULLERVO
IPC: F15B21/041
Filed: 1985-08-20
Abstract: The object of the invention is a reflux filter for hydraulic oil, said filter filters the oil coming from an operating machine before it is returned to the hydraulic system. A frame 1, 2, a bypass tube 3 extending through the frame, a filter element 5 positioned between the bypass tube and frame, a valve 6 to guide the reflux stream of oil through the filter element and valves 4 to guide the forward stream of oil through the bypass tube belong to the filter according to the invention. <IMAGE>
Patent IE-32291-L (IE)
Title: Cephalosporin compounds
IPC: A61K31/545
Filed: 1968-08-20
Abstract: 1,241,656. 3-Etherified cephalosporin derivatives. GLAXO LABORATORIES Ltd. 6 Aug., 1968 [21 Aug., 1967], No. 38493/67. Headings C2A and C2C. [Also in Divisions A5-A6] Novel 7#-acylamino-3-etherified hydroxymethyl-ceph-3-em-4-carboxylic acids are prepared either (a) by N-acylating the corresponding 7#-amino-3-ether, which compounds are also novel, e.g. by reaction with an acid halide, anhydride or mixed anhydride, an active ester or azide, or an acid together with an esterifying agent; or (b) by reacting a 7#- acylamido - 3 - PCH 2 - ceph - 3 - em - 4 - carboxylic acid, wherein P is a group replaceable by an ether group, with an etherifying agent, optionally followed by N-deacylation and reacylation with a different acyl group, preferably by the method of Specification 1,241,655. P may be either a hydroxy or an acetoxy group. When P is hydroxy, etherification may be effected either directly, by reacting the compound with an orthoester such as MC(OR) 3 wherein M is hydrogen, alkyl or -OR and R is the required etherifying radical, or with a diazo compound, or an unsaturated compound activated by electron donating or attracting groups; or indirectly by first converting the 3-hydroxymethyl group to a 3-CH 2 X group where the corresponding acid HX has a pKa of not more than 4, and then reacting the 3- CH 2 X containing compound with an alcohol or phenol to convert X to the required ether group. The group X may be an ester group formed by esterifying the CH 2 OH group with, e.g. halo-, methoxy-, alkylthio-, or cyanoacetic acid, phenyl- or substituted phenylglyoxylic acid or glyoxylic acid itself, phenylpropiolic acid or formic acid; other examples of X are halogen, thio-ether groups, and isothiocyanate groups. When P is acetoxy, this group may be directly displaced by reaction with an alcohol or phenol in a polar medium to give the corresponding ether. In many of these procedures, the 4-carboxyl and 7#-amino group (if present), and any other carboxyl or amino substituent groups present, are protected by easily removable groups, e.g. urethane, trityl, arylmethylene, sulphenyl or enamine groups; alternatively the carboxyl group may be esterified and reaction conditions used wherein the NH 2 group remains protonated. D(-) - α - Formyloxy - α - phenylacetyl chloride is prepared by refluxing in benzene a mixture of D(-)-mandelic acid, p-toluenesulphonic acid and formic acid, to give D(-)-α-formyloxy-α- phenylacetic acid, which is isolated and then refluxed in benzene with thionyl chloride to give the required product.
[GB1241656A]
Patent IE-37897-L (IE)
Title: Solid-state manufacture of polyesters
IPC: C08G63/78
Filed: 1973-07-10
Abstract: 1387335 Solid phase preparation of polyesters IMPERIAL CHEMICAL INDUSTRIES Ltd 2 July 1973 [21 July 1972 14 Nov 1972] 34202/72 and 52551/72 Heading C3R A process for preparing a polyester comprises reacting an aromatic dicarboxylic acid in the solid state with an ester-forming derivative of a diol having no free hydroxyl groups, the reaction conditions being controlled so that throughout the reaction a major part of the reaction mass forms a solid phase. The reaction may be carried out under fluidized bed conditions with the diacid in particulate form and the esterforming derivative in the vapour state, preferably in a chemically inert carrier gas, e.g. nitrogen. When ethylene oxide is used as the esterforming derivative or basic compound catalyst, e.g. 2-hydroxyethyl trimethylammonium hydroxide, triphenyl phosphine or a polyamide, may be present. The examples describe reacting ethylene oxide with terephthalic acid, 1,2-bis- (4 - carboxyphenoxy) - ethane, naphthalene- 2,6-dicarboxylic acid, biphenyl-4,4<SP>1</SP>-dicarboxylic acid or sulphonyl-4,4<SP>1</SP>-dibenzoic acid. The following are also described: (a) reaction of ethylene oxide with naphthalene - 2,7 - dicarboxylic acid, 1,4-diphenoxybutane-p,p<SP>1</SP>-dicarboxylic acid, bibenzyl-4,4<SP>1</SP>-dicarboxylic acid, stilbene-4,4<SP>1</SP>-dicarboxylic acid, 1,2-di-p-carboxybenzoyloxyethane or 1,6-di-p-carboxy-benzamido hexane, and (b) reaction of oxetane and 3,3 - dimethyloxetane with biphenyl - 4,4<SP>1</SP>- dicarboxylic acid and diphenyl sulphone-4,4<SP>1</SP>- dicarboxylic acid.
[GB1387335A]
Patent IE-34522-L (IE)
Title: Lead connection to semiconductors
IPC: H01L21/00
Filed: 1970-09-14
Abstract: A plurality of semiconductor wafers each containing a junction are plated with aluminum on an N conductivity type surface and stacked between P conductivity type attachment wafers. The stack is heated to bond the wafers, gold is plated onto the endmost wafers, and excess aluminum at the periphery of the stack is removed. The wafer stack is subdivided first into slabs and then the slabs repositioned to close the kerf formed by sawing. The repositioned slabs are then subdivided into unitary dice stacks. The unitary dice stacks are then attached to gold coated leads and freed of surface contaminants by flow etching. The cleaned unitary dice stacks are separately protectively encapsulated to form completed rectifiers by first depositing a passivant over the semiconductive surfaces and then molding a plastic housing around the elements.
Patent IE-791288-L (IE)
Title: Herbicidal acetanilides
IPC: A01N43/64
Filed: 1979-08-08
Abstract: Herbicidal agents containing an N-azolylmethylhaloacetanilide of the formula    <IMAGE>  I  where R denotes hydrogen or linear or branched alkyl or alkoxy of a maximum of 5 carbon atoms, R1 denotes hydrogen, halogen, or linear or branched alkyl or alkoxy of a maximum of 5 carbon atoms, R2 denotes hydrogen, halogen, or linear or branched alkyl or alkoxy of a maximum of 5 carbon atoms, R together with R2 forms an alkylene chain of a maximum of 6 carbon atoms which is linked in the o-position and is unsubstituted or substituted by linear alkyl of a maximum of 4 carbon atoms, X denotes chlorine or bromine, and A denotes an azole which is attached via a ring nitrogen atom and is unsubstituted or mono- or poly-substituted by halogen, phenyl, alkyl, alkoxy, alkylthio or perfluoroalkyl, each of a maximum of 4 carbon atoms, cyano, carboxy, carbalkoxy of a maximum of 4 carbon atoms in the alkoxy, or alkanoyl of a maximum of 4 carbon atoms, A also denoting a salt of an azole containing 2 or 3 nitrogen atoms, and a haloacetanilide of the formula    <IMAGE> II  where R denotes linear or branched alkyl, alkenyl or alkynyl, each of a maximum of 4 carbon atoms, or -A-R1, A denoting alkylene of 1 or 2 carbon atoms which may be monosubstituted by ethyl or mono- or disubstituted by methyl, and R1 denoting linear or branched alkoxy, haloalkoxy, alkenoxy, alkynoxy or alkoxyalkoxy, each of a maximum of 4 carbon atoms, cycloalkoxy or cycloalkylmethoxy with 3 to 6 carbon atoms in the cycloalkyl ring, 1,3-dioxolan-2-yl or alkoxycarbonyl of a maximum of 4 carbon atoms in the alkoxy, X denotes chlorine or bromine, and Y1 and Y2 are identical or different and each denotes hydrogen or linear or branched alkyl of a maximum of 4 carbon atoms, Y1 and Y2 only denoting hydrogen when R is linear or branched alkyl, alkenyl or alkynyl, each of a maximum of 4 carbon atoms. The ratio of N-azolylmethylhaloacetanilide of the formula I to haloacetanilide of the formula II is from 1:0.5 to 1:20 parts by weight.
Patent IE-41177-L (IE)
Title: Longitudinal cutting of foil in band form
IPC: B26D1/03
Filed: 1975-07-02
Abstract: 1513456 Cutting apparatus VAW LEICHMETALL GmbH 8 July 1975 [8 July 1974] 28685/75 Heading B4B An apparatus for the longitudinal cutting of soil in strip form comprises at least two blades 7, 7<SP>1</SP> arranged one behind the other in the direction of travel of the strip, the blades being spaced apart in the direction of width of the strip and angled towards one another in the direction of travel of the strip. 
The two blades 7, 7<SP>1</SP> i.e. razor blades, are mounted in a cutting head 8 which is connected to the piston of an hydraulic ram 9 slidably mounted on a rail 2, the ram being locked in a selected position by a lever 3. 
A pneumatic sensing device 6, Fig. 1 is mounted on the piston rod and controls the position of the cutting head relative to the surface of the strip material. 
The cutting head may be pivoted to bring the blades into a position in which they are protected by a guard 14. 
In a modification the hydraulic ram may be replaced by a pneumatically or electrically driven servo-motor. 
(From GB1513456 A) 
[FR2277655A1]
Patent IE-43505-L (IE)
Title: Recovery of zearalenone.
IPC: C12R1/645
Filed: 1976-07-28
Abstract: Zearalenone is recovered from an aqueous mixture including zearalenone, water, and undissolved solids by a method comprising dissolving the zearalenone by contacting it with a zearalenone-dissolving mixture of water and a water-miscible, organic solvent, removing the undissolved solids, increasing the proportion of water to organic solvent to precipitate the zearalenone, and recovering the precipitated zearalenone.
[US4010167A]
Patent IE-891819-L (IE)
Title: Essential fatty acid compositions
IPC: A61K31/355
Filed: 1989-06-12
Abstract: Method of, and preparations of medicaments for, treating schizophrenia and/or associated tardive dyskinesia by combining an essential fatty acid selected from GLA and higher n-6 series acids with an essential fatty acid selected from stearidonic acid and higher n-3 series acids in effective daily amounts of 10 mg and 50 g of each acid and with Vitamin E in addition.
Patent IE-791892-L (IE)
Title: Crimped polyester yarn
IPC: D02G1/14
Filed: 1979-10-05
Abstract: Hitherto the commercial production of a gear crimped polyester yarn has not proved practicable due to extremely low bulk in the yarn and inadequate yarn mechanical properties. There is now provided a drawn gear-crimped polyester yarn with latent bulk the amount and nature of the bulk being such that the yarn has an initial crimp as defined of at least 1.5%, preferably of above 2%, and a mechanical crimp stability as defined of above 0%. The crimped polyester yarn may be produced by heating a drawable polyester yarn (9) having a birefringence in the range 32 x 10<-><3> to 125 x 10<-><3> inclusive, preferably 35 x 10-<3> to 125 x 10<-><3> inclusive, crimping the yarn by guiding it between the intermeshing teeth of a set of toothed wheels (11,19) such that the yarn is caused to follow a sharply zig-zag path, the toothed wheels being rotated at a sufficient speed such that the yarn is drawn by the tension so imparted to the yarn by the toothed wheels and subsequently forwarding the crimped yarn from the toothed wheels under a controlled tension within the range 0.15 to 0.50 g per decitex inclusive based on the decitex of the drawn polyester yarn.
Patent IE-802141-L (IE)
Title: Vaccine
IPC: C12N7/08
Filed: 1980-10-15
Abstract: The invention provides a live feline infectious peritonitis vaccine comprising an amount of live feline infectious peritonitis virus capable of inducing immunity in animals of the genus Felis, family felidae against feline infectious peritonitis without serious side effects and a pharmaceutically acceptable carrier. The vaccine can be prepared by a process which comprises propagating susceptible feline cells infected with feline infectious peritonitis virus at a physiological temperature, harvesting the resulting viral material and mixing it with a pharmaceutically acceptable carrier.