baber/WOPTO huggingface dataset:
Patent DE-68925588-D1 (DE)
Inventor: NGO THAT
IPC: B01D15/08
Filed: 1989-11-27
Granted: 1996-03-14
Abstract: A novel class of compounds, methods for the preparation thereof and the use thereof in chromatographic methods for binding various biologically active materials non-covalently are disclosed. The class of compounds comprises the reaction product of a polymeric gel with a pyridine base, such as 4-dimethylaminopyridine (DMAP), and a halogen-substituted pyridine, such as 3,5-dichloro-2,4,6-trifluoropyridine (DCTFP), which reaction product may in turn be optionally reacted with hydroxyl ions or specified low-molecular-weight compounds. These compounds are capable of selectively and efficiently binding proteins and other organic materials of interest non-covalently to a degree comparable or superior to the heretofore preferred natural affinity ligands, such as Protein A gels. The novel compounds find particular utility in purification and recovery of proteins such as serum albumin and immunoglobulins of various classes from crude sources, such as diluted serum samples from various species.
Patent DE-69013396-D1 (DE)
Inventor: KELLEY JAMES LEROY
IPC: A61P25/00
Filed: 1990-04-20
Granted: 1994-11-24
Abstract: There is disclosed a series of triazolopyrimidine compounds and pharmaceutical compositions containing them. The disclosed compounds are useful in the treatment of central nervous disorders, such as epilepsy, in mammals. Methods for the preparation of these triazolopyrimidines are also disclosed.
Patent DE-69016958-D1 (DE)
Inventor: GERTZ DAVID C
IPC: E01F15/04
Filed: 1990-11-16
Granted: 1995-03-23
Abstract: A vehicle crash barrier (10) for decelerating a vehicle that has left a roadway includes an elongated frame having a number of sections (14, 16, 18) including a front section (14) and at least one additional section (16, 18) arranged end to end along an axial direction. The frame is configured to collapse when axially struck on the front section (14) by a vehicle. A wire cable (122) extends generally parallel to the frame and has a forward end portion anchored independently of the frame and a rearward end portion. Friction brakes (140) are mounted to the front section for engaging the wire cable (122) to generate a retarding force to decelerate a vehicle as the brake (140) moves along the wire cable (122) during collapse of the frame following impact of the vehicle against the front section (14). Each section includes a pair of side panels (42), and axially adjacent side panels are connected by a flexible tension strap (46) by fasteners (44). The tension strap (46) operates to peel the fasteners (44) out of the side panels during axial collapse. The front section (14) is releasably secured to a ground anchor (80) by a directionally sensitive breakaway assembly. (100) .
Patent DE-69022326-D1 (DE)
Inventor: LOK ROGER
IPC: C07D277/62
Filed: 1990-07-26
Granted: 1995-10-19
Abstract: Latent image stability is enhanced in photographic recording materials using ester containing N-alkyl- or N-alkenylbenzothiazolium or -benzoselenazolium salts.
Patent DE-69022538-D1 (DE)
Inventor: WIDMER LINCOLN ALBERT
IPC: C08J7/06
Filed: 1990-11-06
Granted: 1995-10-26
Abstract: The invention relates to a composition for coating wet rubber particles during extrusion and pelletization prior to drying comprising an inorganic partitioning agent, a thickener and binder reagent, water and a water soluble anionic dispersant, and to the process for application to elastomers including those of low viscosity or high resin content to improve their processability during manufacture.
Patent DE-69027051-D1 (DE)
Inventor: GUERET JEAN-LOUIS
IPC: B65D47/28
Filed: 1990-07-20
Granted: 1996-06-20
Abstract: A dispenser for a fluid substance, esp. used in cosmetics or pharmaceuticals, consists of a cap (1) which fits onto the container (2) and made with at least one outlet channel (8). The/each outlet channel has a system which closes its outlet, made in the form of a shutter (9a) which is able to deform elastically and interact with a seat (8e). The deforming shutter and seat form a self-closing valve which is opened by the pressure of the fluid passing through it but closes once the pressure stops. The shutter is pressed towards the seat by a support which limits its deformation. The pressure which expels the fluid from the container can be of various types, e.g. a pump piston or flexible bulb.
Patent DE-69032526-D1 (DE)
Inventor: MOGENSEN KNUD
IPC: C12P21/08
Filed: 1990-10-19
Granted: 1998-09-03
Abstract: The invention relates to the human alpha receptor interferon and to the DNA sequence, in particular the cDNA sequence, characterized by the fact that it codes for the alpha interferon receptor gene. Furthermore, the invention relates to the non human cells which express said receptor, to a process for obtaining said cells, to a process for the preparation of a protein corresponding to said DNA fragment, to the protein thus obtained, and to the antibodies raised against said protein. The invention also relates to diagnostic kits based on said receptor and to the use of said receptor to identify human alpha IFN agonists.
Patent DE-69101086-D1 (DE)
Inventor: JOUVAUD DOMINIQUE
IPC: F27B14/06
Filed: 1991-06-19
Granted: 1994-03-10
Abstract: Process for melting a furnace charge, with post-combustion of the smokes by injecting an oxygenated gas in the furnace atmosphere as a series of jets flowing according to a tangential component in the space between electrodes and cylindrical furnace partition of the furnace, in a direction of injection so as to produce a rotary gas current about the vertical axis of the furnace and preferably in at least two series as two stepped levels to produce gas currents which rotate in opposite directions. Applications to electrical furnaces for the production of steel or ferro-alloys.
Patent DE-69110043-D1 (DE)
Inventor: CLARK CHARLES
IPC: B23K11/25
Filed: 1991-05-29
Granted: 1995-06-29
Abstract: An adaptive stepper for adjusting welding heat boost to compensate for deterioration (flattening) of the electrode tips of a welder. Heat boost is provided to the welder as a function of expulsion rather than by a series of linear step profiles specified by a weld engineer. An operator sets up an adaptive schedule based upon an expected resistance difference between consecutive half-cycles considered to be "normal." If differences equal to or less than the normal level are detected during a group of welds, the heat boost will be incremented by 1% after a preprogrammed number of welds have been made. If differences greater than normal are detected, indicating expulsion, the boost will be decremented immediately by 1% between increases, if decrements are allowed at the time.
Patent DE-69116192-D1 (DE)
Inventor: POURQUIE JACQUES
IPC: C12N9/42
Filed: 1991-02-27
Granted: 1996-02-22
Abstract: The composition is obtained by a process in which at least one strain of Trichoderma reesei is brought into contact with a carbonaceous fermentation medium comprising a supply of water-soluble sugars, which consists at least in part of a raw extract of water-soluble pentoses originating from a pretreated lignocellulosic substrate. Application to the hydrolysis of substrates such as deciduous wood, cereal straw and maize stalks.
Patent DE-69133214-D1 (DE)
Inventor: LUBKIN VIRGINIA
IPC: A61K9/06
Filed: 1991-08-17
Granted: 2003-04-17
Abstract: A topical drug application for the alleviation of keratoconjunctivitis sicca (dry eye syndrome) is comprised of a solution of sex steroids or their derivatives suspended or dissolved in a vehicle, and the method of preparation and application of the same. In the preferred embodiments, the sex steroid consists essentially of conjugated estrogen in a lipid vehicle or a derivative of estrogen known as 17 beta-Estradiol 3-phosphate disodium dissolved in an aqueous vehicle having a pH of between 6 and 8.
Patent DE-69207701-D1 (DE)
Inventor: BALLESTRAZZI ARIS
IPC: B65B9/067
Filed: 1992-10-09
Granted: 1996-02-29
Abstract: An apparatus for stretching a continuous plastics film in a packaging machine (11), in which products (12) fed one after the other are wrapped and sealed within said continuous film, comprising a first conveyor belt (13), a transverse welding apparatus (14) and a second conveyor belt (18), in which the transverse welding apparatus consists of a horizontally traversing carriage (15) which supports a pair of superposed welding bars (16,17) and a pressing belt (46) facing the second conveyor belt. The conveyor belts are driven by a speed variator (21) via a pair of transmissions, the first of which drives an end roller of the first conveyor belt and the second drives an end roller of the second conveyor belt by way of a linkage which varies the speed of the two conveyor belts, there being also provided upstream of said transverse welding apparatus, both above the first conveyor belt and operationally linked to the vertical movement of the upper welding bar (16), elements for clamping (51) the film onto the products (12) wrapped in it. <IMAGE>
Patent DE-69208579-D1 (DE)
Inventor: ESTOP PASCAL
IPC: H01B7/00
Filed: 1992-10-08
Granted: 1996-04-04
Abstract: The invention relates to a power lead for a use under variable operating conditions, in particular for alternating operating conditions, and for connecting a device placed in a non-cryogenic environment to a device placed in a cryogenic environment. In order to reduce losses, this power lead consists of at least one conductor (1) formed by filaments (2) of a high-purity metal, these filaments being embedded in a matrix (3) of a resistive metal alloy. <IMAGE>
Patent DE-69213057-D1 (DE)
Inventor: UENO RYUJI
IPC: A61K31/5575
Filed: 1992-03-10
Granted: 1996-10-02
Abstract: A use of a 15-keto-prostaglandin compound for the manufacture of a medicament for promoting healing of wound.
Patent DE-69216439-D1 (DE)
Inventor: WESTHOF LUC BRUNO JOZEF
IPC: C04B22/06
Filed: 1992-02-11
Granted: 1997-02-20
Abstract: A cementitious composition which contains a base which preferably has a solubility which is greater than that of calcium hydroxide. The amount of this base is such as to provide 0.1 to 2% by weight of hydroxide relative to the weight of the cementitious composition. The cementitious composition may be a polymer modified mortar which is used as the anode overlay in a cathodically protected reinforced concrete.
Patent DE-69222653-D1 (DE)
Inventor: SANKEY GEOFFREY PHILLIP
IPC: E06B7/36
Filed: 1992-10-29
Granted: 1997-11-13
Abstract: PCT No. PCT/GB92/01978 Sec. 371 Date Jun. 15, 1994 Sec. 102(e) Date Jun. 15, 1994 PCT Filed Oct. 29, 1992 PCT Pub. No. WO93/09325 PCT Pub. Date May 13, 1993.A door jamb finger guard is described which comprises four elongate strips (10, 12, 14, 16) that are hinged to one another along their edges. The free edges of the first (10) and fourth (16) strips are pivotably connected to two further strips (18, 20) which in use are secured to the door (26) and to the door jamb (24) respectively. The first strip (10) is wider than the fourth strip (16) so as to force the strips (10, 12, 14, 16) to lie against one another when the door (26) is closed.
Patent DE-69226949-D1 (DE)
Inventor: LAGARDE ALAIN
IPC: A61K38/00
Filed: 1992-03-25
Granted: 1998-10-15
Abstract: Described is a purified osteogenic factor that when delivered to bone in association with a physiologically acceptable delivery vehicle is capable of inducing new bone growth at the bone surface. The osteogenic factor is water soluble, and is characterized physically by a molecular weight of about 2.5 kD when measured by gel filtration under dissociating conditions and an isoelectric point in the pH range from about 4.6 to 7.2. Use of the purified factor in treating bone defects is described. Also described is a method for obtaining the purified factor from mammalian bone.
Patent DE-69231311-D1 (DE)
Inventor: OCCHETTO SERGIO
IPC: H01H35/00
Filed: 1992-04-30
Granted: 2000-09-07
Abstract: Pulse formers (14) driving respective LEDs (12) are energized by the cells of a shift register (16) clocked by a clock line (CK), and to whose first cell an initial pulse is applied by a first signal generator (GR). A barrier-end line (FB) is connected to the output of the shift register and to the input of the first signal generator. The latter resets the shift register cells through a reset line (RS). a plurality of photodiodes (42) facing the LEDs are connected in common to a bus line (BUS) through electronic switches (44) which are closed in turn by the cells of a shift register (46) similarly controlled by a second signal generator (GE) in synchronism with the first. The two shift registers, including the associated LEDs or photodiodes may form blocks connected in cascade. <IMAGE>
Patent DE-69232497-D1 (DE)
Inventor: NABEL G
IPC: A61K47/48
Filed: 1992-06-26
Granted: 2002-04-25
Abstract: A method for the direct treatment towards the specific sites of a disease is disclosed. This method is based on the delivery of proteins by catheterization to discrete blood vessel segments using genetically modified or normal cells or other vector systems.Endothelial cells expressing recombinant therapeutic agent or diagnostic proteins are situated on the walls of the blood vessel or in the tissue perfused by the vessel in a patient. This thechnique provides for the transfer of cells or vectors and expression of reccombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of diseases.
Patent DE-69232807-D1 (DE)
Inventor: AKAOGI TAKAO
IPC: G11C16/04
Filed: 1992-12-09
Granted: 2002-11-07
Abstract: A negative-voltage bias circuit is provided which comprises: a capacitor (550) having first and second terminals (550B, 550A) ; a first p-channel MIS field-effect transistor (551) whose drain is connected to a negative-voltage output terminal (554) and whose gate and source are connected to the first terminal (550B) of the capacitor (550); and a second p-channel MIS field-effect transistor (552) whose drain is connected to the source of the first p-channel MIS field effect transistor (551), whose gate is connected to the negative-voltage output terminal (554), and whose source is provided with a negative voltage (VBB). The first p-channel MIS field-effect transistor (551) is a depletion-type p-channel MIS field-effect transistor. In operation of the circuit, application to the second terminal (550A) of a series of clock pulses (CLK) causes a potential of the negative-voltage output terminal (554) to tend towards the negative voltage (VBB). <IMAGE>
Patent DE-69318033-D1 (DE)
Inventor: BISSERY MARIE-CHRISTINE
IPC: A61K33/243
Filed: 1993-11-08
Granted: 1998-05-20
Abstract: Combinations of (a) taxol, taxotere, or their derivatives, with (b) a therapeutic substance are used in the treatment of neoplastic disorders. Pref., (b) is an alkylating agent, (esp. cyclophosphamide, ifosamide, melphalan, hexamethyl melamine, thiotepa, and dacarbazine), an anti-metabolite, (esp. 5-fluorouracil, cytarabin, methotrexate, idatrexate, and trimetrexate), a fusel poison (esp. a vinca alkaloid, their synthetic and semi-synthetic analogues, estramustine, and taxoids), an epidophyllotoxin, (esp. etoposide or teniposide), an antibiotic, esp. daunorubicin, doxorubicin, bleomycin, or mitomycin), an enzyme (esp. L-asparaginase), a topoisomerase inhibitor, (esp. camptothecin, CPT-11, topotecan, and pyridobenzoindole derivatives), procarbazine, mitoxantrone, platinum coordination complexes (esp. cisplatin and carboplatin), biological response modifiers and growth inhibitors, (esp. interferons and interleukins), and haematopoietic growth factors. The taxane derivative (a) may comprise 10-90% of the active materials.
Patent DE-69322369-D1 (DE)
Inventor: ABELE MANILO
IPC: G01R33/383
Filed: 1993-08-18
Granted: 1999-01-14
Abstract: A magnetic construction having a rectangular cross section cavity (20) with a uniform magnetic field therein, comprising an element of high-permeability material (30) having a flat surface and positioned to define one wall of said cavity (20), and a magnetic structure (10-14) at least partly of permanent magnetic material defining three further walls of said cavity (20), said magnetic structure (10-14) having a surface spaced from said flat surface of said element of high permeability material (30), said flat surface and the surface of said structure of magnetic material (10) defining opposed walls of said cavity (20), wherein the magnetic construction further comprises a partial yoke (65) on said magnetic structure (10-14) and spaced from said flat surface, and a magnetic shunt (80) of a magnetic material of remanence lower than that of said magnetic structure (10-14) extending between said yoke (65) and said flat surface. <IMAGE>
Patent DE-69322495-D1 (DE)
Inventor: ABRAMS ROBERT
IPC: B31B1/84
Filed: 1993-09-30
Granted: 1999-01-21
Abstract: A method of and apparatus for attaching a spout to a planar portion of an article such as a milk or juice carton, which may be integrated into conventional carton forming and filling machines, includes the steps of heating a stem of a spout, applying a bonding agent to a flange on the spout, positioning the spout in a predetermined relation to a spout applicator, positioning a carton with a hole provided in a predetermined relation to the spout applicator and attaching the spout to the carton where the heated stem is deformed to mechanically engage the carton about the hole. An apparatus to accomplish the method is also disclosed.
Patent DE-69324116-D1 (DE)
Inventor: ERICKSON DWIGHT D
IPC: C09K3/14
Filed: 1993-12-14
Granted: 1999-04-29
Abstract: Alumina-based abrasive grain comprising rare earth oxide and calcium oxide and/or strontium oxide, and a method of making the same. The abrasive grain is useful in abrasive articles, such as coated abrasives, three-dimensional, low density abrasives, and bonded abrasives. <IMAGE>
Patent DE-69324673-D1 (DE)
Inventor: KENNELLY TERESA
IPC: F23C13/00
Filed: 1993-03-01
Granted: 1999-06-02
Abstract: A process for operating a palladium oxide-containing catalytic combustor is useful, e.g. for powering a gas turbine. The palladium oxide is supported on a metal oxide such as alumina, lanthanide metal oxide-modified alumina, ceria, titania or tantalum oxide. The method involves maintaining control of the temperature within the combustor in such a manner as to insure the presence of palladium oxide. By maintaining the temperature below the decomposition onset temperature of palladium oxide (which is catalytically active for catalytic combustion) into metallic palladium (which is catalytically inactive) deactivation of the catalyst is avoided and high catalytic activity is retained. Regeneration of catalyst following inactivation resulting from an over-temperature is accomplished by using a heat soak in a regeneration temperature range which varies depending on the particular metal oxide used to support the palladium oxide. <IMAGE>
Patent DE-69330367-D1 (DE)
Inventor: STEFANCHIK DAVID
IPC: A61B17/128
Filed: 1993-09-13
Granted: 2001-07-26
Abstract: An improved surgical instrument and sterile clip for ligating the vessel of a mammal. The clip has a pair of legs which are urged apart by the instrument to allow the clip to be placed on the vessel to be ligated.
Patent DE-69408270-D1 (DE)
Inventor: VON BUREN STEFAN
IPC: B29C48/74
Filed: 1994-11-08
Granted: 1998-03-05
Abstract: An improved heater clamp arrangement for use in molding including channel means for transferring molten plastic, a sheet-like band heater (50) around at least a portion of the channel means for heating the channel means and molten plastic, and means (56) placing continuous pressure on the band heater to urge same towards the channel means in the hot and cold condition, as a sheet-like strip. <IMAGE>
Patent DE-69409549-D1 (DE)
Inventor: BENTSEN JAMES
IPC: A61B5/145
Filed: 1994-08-18
Granted: 1998-05-14
Abstract: The present invention relates to a sensing instrument and method for measuring the concentration of an analyte. The sensing instrument includes: a sensing element including at least a first emissive indicator characterized by a bimolecular quenching rate constant kq, one or more fluorescence lifetimes  tau o above a lowest lifetime  tau oL, and capable of emitting analyte concentration dependent signals when exposed to an excitation signal in the presence of quencher; an excitation system which provides an amplitude modulated excitation signal at one or more radial modulation frequencies  omega ; a detector; and a processor. The processor univariantly processes the detected signals and provides output signals representative of analyte concentration. The sensing element and/or excitation system are configured to enable the instrument to operate sufficiently within the condition [(kq[Q])2+ omega 2] tau o2>>1+2kq tau o[Q] such that a slope of the relationship between the concentration dependent parameter and analyte concentration is independent of  tau o variability and/or heterogeneity for all analyte concentrations within the operating range and for all lifetimes  tau  o greater than  tau oL.
Patent DE-69419157-D1 (DE)
Inventor: LOWE JOHN
IPC: A61P1/00
Filed: 1994-05-19
Granted: 1999-07-22
Abstract: PCT No. PCT/IB94/00111 Sec. 371 Date Jan. 18, 1996 Sec. 102(e) Date Jan. 18, 1996 PCT Filed May 19, 1994 PCT Pub. No. WO95/03281 PCT Pub. Date Feb. 2, 1995This invention relates to compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the application. These compounds are CCK-B receptor antagonists and are useful in the treatment and prevention of central nervous system and gastrointestinal disorders.    <IMAGE>  (I)
Patent DE-69419615-D1 (DE)
Inventor: BARRETT PAUL ALEXANDER
IPC: H04Q1/46
Filed: 1994-09-14
Granted: 1999-08-26
Abstract: Speech is distinguished from noise by a spectral comparison of an input signal with a stored noise estimate. Updating of the noise estimate stored in a buffer is permitted during periods when speech is absent under control of an auxiliary detector. In order to improve operation in the presence of signals with strong harmonic components, e.g., signaling tones, an LPC prediction gain is computed from the input (x(i)) and a residual (y(i)) obtained from the input following filtering by a filter having a response complementary to the frequency spectrum of the input, and if the gain exceeds a threshold, buffer updating is suppressed.
Patent DE-69424671-D1 (DE)
Inventor: MORGANTINI GIANPIERO
IPC: A61L11/00
Filed: 1994-07-18
Granted: 2000-06-29
Abstract: PCT No. PCT/EP94/02357 Sec. 371 Date Mar. 18, 1996 Sec. 102(e) Date Mar. 18, 1996 PCT Filed Jul. 18, 1994 PCT Pub. No. WO95/03072 PCT Pub. Date Feb. 2, 1995A method for heat sterilizing or disinfecting hospital waste includes the steps of grinding and/or comminuting the waste under a cutting force and for an amount of time such that a quantity of heat which is sufficient to reach and maintain the sterilization or disinfection temperature within the massive waste is generated by friction. The apparatus includes a rotor provided with vanes or blades for grinding or comminuting the waste and a plurality of fixed strikers in the form of vanes or blades associated with the walls of the housing.
Patent DE-69426524-D1 (DE)
Inventor: ANDERSSON ANDERS
IPC: B07B1/46
Filed: 1994-04-28
Granted: 2001-02-08
Abstract: PCT No. PCT/SE94/00380 Sec. 371 Date Nov. 7, 1995 Sec. 102(e) Date Nov. 7, 1995 PCT Filed Apr. 28, 1994 PCT Pub. No. WO94/26427 PCT Pub. Date Nov. 24, 1994A vibrating screen for the sizing of granular material such as gravel, sand, crushed stone, etc., having a frame (1) and a screen body (2) supported on springs (6), directional oscillating movements being imparted to the screen body by a motor powered vibrator mechanism (3). The screen has two or more screen decks (11-13), each one divided into three component screens (14a-c, 15a-c, 16a-c) having successively decreasing inclinations in a direction towards the discharge end (9) of the screen, each lower screen deck furthermore having an increased inclination in relation to the nearest deck above.