baber/WOPTO huggingface dataset:
Patent EP-2180007-B2 (EP)
Inventor: UMAÑA PABLO
IPC: C07K16/30
Filed: 1999-04-20
Granted: 2017-08-30
Abstract: The present invention provides a method for generating a host cell that produces a recombinant antibody with enhanced Fc-mediated cellular cytotoxicity, comprising: providing a host cell that is capable of expressing a recombinant antibody comprising an IgG Fc region containing N-linked oligosaccharides and genetically modifying the host cell to alter the glycosylation pattern of the antibody; wherein said recombinant antibody has an increased proportion of GlcNAc residues in the Fc region relative to the proportion of fucose residues and has increased Fc-mediated cellular cytotoxicity compared to the corresponding antibody produced by the same host cell that has not been genetically modified. The present invention also provides a method for producing a protein compound having enhanced Fc-mediated cellular cytotoxicity in a host cell. The present invention further provides a glycosylation engineered host cell that expresses a recombinant antibody comprising an IgG Fc region containing N-linked oligosaccharides, wherein said host cell has been genetically modified to regulate the expression of at least one nucleic acid encoding a glycoprotein modifying enzyme, and wherein said antibody has increased ADCC.
Patent EP-0002648-B2 (EP)
IPC: G04F1/00
Filed: 1978-12-12
Granted: 1988-11-09
Abstract: 1. Time switch with a member determining the time and a contact device controllable thereby, whereby the member determining the time is formed as an electronic generator of which the period is shorter than a preselected time interval to be measured, and whereby the frequency of the generator is divided in a resetable electronic frequency divider, characterized in that the time switch is adapted to be connected to a common switching-on and reswitching line (E, N), in such a way, that the frequency divider is at least partially resetable from any state through this common line.
Patent EP-0420663-B2 (EP)
Inventor: GEBHART WALTER M
IPC: F27D21/04
Filed: 1990-09-28
Granted: 1999-06-23
Abstract: An alignment measuring system is used in determining the location of the rotational centre line of a long, cylindrical body having a number of support bearings spaced along its length, during the rotation of the body. The method particularly lends itself to the re-alignment of hot kilns, during their operation, without requiring shut down and the consequent disruption and loss of product. The system utilizes a base line or datum on each side of the kiln for locating the measuring instrument. The distance measuring instrument is a radiant beam instrument such as a diode laser providing an electronic readout, to enable accurate determination of the distance of the outer surface of the kiln shell from the instrument, and hence the location of the rotational centre relative to the established baseline datum, for the longitudinal station being measured. A series of lateral centre line determinations thus made along the length of a kiln, and including a like determination of the height of the centre line at each measuring station, permits adjustment to selected ones of the kiln support bearings to align the rotational centre line along the length of the kiln, including the correction of centre line elevations.
Patent EP-0594810-B2 (EP)
Inventor: PRECHTEL MICHAEL
IPC: B21K1/42
Filed: 1993-04-02
Granted: 2003-01-02
Abstract: PCT No. PCT/EP93/00828 Sec. 371 Date Nov. 30, 1993 Sec. 102(e) Date Nov. 30, 1993 PCT Filed Apr. 2, 1993 PCT Pub. No. WO93/21352 PCT Pub. Date Oct. 28, 1993In order to simplify the production of a nigh-resistance bobbin body made of an aluminum alloy, the following process steps are performed: (a) extruding or flow extruding an essentially cylindrical bobbin blank; (b) cutting the bobbin blank to a length including the desired bobbin body length plus an overlength sufficient to form end flanges on the bobbin body; (c) shaping end flanges at both ends of the bobbin body from the overlength portion; hardening the bobbin body; and age-hardening (aging) the bobbin body. Various process parameters are described.
Patent EP-0741762-B2 (EP)
Inventor: HAYASHI RYUICHI
IPC: C08L77/00
Filed: 1995-01-25
Granted: 2004-04-07
Abstract: A polyamide resin composition having good molding fluidity, heat and chemical resistance and dimensional stability is provided containing: (A) 30-90 weight percent, based on components (A) and (B), of a polyamide resin containing (i) 10-99 weight percent, based on components (i) and (ii) of an aromatic polyamide containing a carboxylic acid component derived from terephthalic acid or a mixture of terephthalic and isophthalic acid in which the isophthalic acid constitutes 40 mole percent or less of the mixture, and an aliphatic diamine component derived from a mixture of hexamethylene diamine and 2-methylpentamethylene diamine; and (ii) 1-90 weight percent, based on components (i) and (ii), of at least one polyamide selected from the group consisting of polyamides containing repeat units derived from alipathic dicarboxylic acids and alipathic diamines and polyamides containing repeat units derived from aliphatic aminocarboxylic acids; and (B) 10-70 weight percent, based on components (A) and (B), of an inorganic filler.
Patent EP-1018839-B2 (EP)
Inventor: WEIS TIM
IPC: B60R1/00
Filed: 1999-12-14
Granted: 2010-01-20
Abstract: The method involves detecting the rear view zone with at least one sensor element (30) and forming an image of it on at least one display device. The zone of observation related to the door mirrors is divided into two observation zones (10,20) covering different angular ranges that are displayed on the display device with an inversely proportional breadth relationship.  An Independent claim is also included for an arrangement for displaying the rear view for motor vehicle.
Patent JP-2960103-B2 (JP)
IPC: A62D3/33
Filed: 1990-04-16
Granted: 1999-10-06
Abstract: A process for the treatment of heavy residues originating from the manufacture of chlorinated products in which a chemical compound chosen from certain fatty compounds is added to the heavy residues in order to form fluid and stable liquid suspensions. 
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Patent JP-2710628-B2 (JP)
IPC: G03C1/775
Filed: 1988-05-13
Granted: 1998-02-10
Abstract: The waterproof base for light-sensitive materials is coated on one or both sides with polyolefin resin, at least the polyolefin resin of the front coating containing a copolymer of ethylene and another  alpha -olefin. This copolymer makes it possible to add a high proportion of light-reflecting white pigment to the coating composition.
Patent JP-2829342-B2 (JP)
IPC: C07D213/64
Filed: 1990-05-11
Granted: 1998-11-25
Abstract: A process for the preparation of 3,5,6-trichloropyridin-2-ol from trichloroacetyl chloride and acrylonitrile is improved by separately conducting the individual addition, cyclization and aromatization steps. By separating these steps, water and HCl, which are by-products of the latter steps, can be precluded from interfering with the earlier steps. The individual process steps have also been improved.
Patent JP-3795628-B2 (JP)
IPC: H05K1/02
Filed: 1997-05-16
Granted: 2006-07-12
Abstract: PROBLEM TO BE SOLVED: To enable suppression of stresses to a connection part caused by connecting a semiconductor chip to an external wiring board, even when a volume of projected terminals of a semiconductor device is decreased with an increased number of output terminals of the semiconductor chip, to thereby secure a connection reliability. SOLUTION: A wiring board 17 is provided on its solder ball mounting side with a base material 6, made of a BT resin glass cloth or an epoxy resin glass cloth. Formed on the base material is a buffer layer 7 having an elastic modulus of 0.5-5 kgf/mm<2> . Formed on the buffer layer is a pad electrode 10, on which wiring and solder balls 11 are formed. The solder balls 11 are made of a composition with Sn and Pb in an Sn/Pb ratio of 6:4.
Patent JP-H0672342-B2 (JP)
IPC: D03D47/27
Filed: 1986-06-04
Abstract: Improved means for guiding the weft-carrying grippers and their control straps through the shed of gripper looms comprise a single plurality of guide elements (3) aligned on the sley (1), each element (3) being provided with at least two distinct seats (4, 5) for housing respectively the strap (6) and the gripper (8), the seat (5) housing the gripper (8) being apt to prevent - either by itself or in cooperation with the seat (4) for the strap (6) - any lateral or upward movements of said gripper (8).
Patent JP-H0317588-B2 (JP)
IPC: B22D41/08
Filed: 1988-06-06
Abstract: The intention is to improve the introduction of flushing gas via the closed gate plate (6) in order to achieve if possible a one hundred per cent spontaneous outflow rate after the opening of the gate. When a predetermined backpressure of the flushing gas is reached and/or immediately prior to the opening of the gate plate (6), at least one jet produced by a pressure wave of at least 12 bar frees blockages arising in the nozzle (1) for spontaneous flow. 
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Patent JP-H0675691-B2 (JP)
IPC: B05B3/10
Filed: 1987-06-11
Abstract: A rotary element (8), for distributing liquids such as herbicide, comprises a concave liquid receiving surface (22) including a conical outer portion (26). Teeth (28) project from the outer portion (26). Each tooth has an upper surface (30) which is inclined to the rotary axis of the element by a greater angle than is the outer portion (26). Each tooth has side surfaces (32) which extend parallel to the rotary axis and have a maximum axial dimension (t) which is greater than 0.01, and preferably 0.05, times the overall diameter of the element.
Patent JP-H0153280-B2 (JP)
IPC: C07J1/00
Filed: 1980-10-27
Abstract: 17 alpha -substituted steroids of the formula   <IMAGE>   wherein R1 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl, R2 is alkyl or alkenyl of 2-6 carbon atoms, X is oxygen or the grouping H(OR3) wherein R3 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl, upon topical application, display antiandrogenic properties and can be utilized for the treatment of acne, seborrhea, alopecia and hirsutism.
Patent JP-H0446744-B2 (JP)
IPC: B29D99/00
Filed: 1982-09-22
Abstract: Process for the netlike opening of fibrilled polymeric films, said process consisting in conveying to an opening device of the conventional type (based, for instance, on diverging transferring elements and on lateral film pulling elements such as clamps, grippers or pins, which engage the film at its edges and which are fixed on said traverse elements) the fibrilled film of an undulated or corrugated shape, with the front of the corrugations or waves perpendicular to the direction of the transferring motion, so that the length of the film between the lateral consecutive pulling elements be in excess with respect to the distance between said elements, wherefore said excess will compensate the longitudinal shrinkage that the film will suffer during the transversal opening.
Patent JP-H0458985-B2 (JP)
IPC: A61L27/00
Filed: 1985-07-29
Abstract: This invention relates to a biodegradable anchor for a permanent implant of a bone joint, e.g. hip, shoulder, knee or finger. The biodegradable anchor (14, 32) is an elongated member which has an exterior surface which tightly engages a cavity in the bone and is substantially immovable within the cavity upon implant. A non-resorbable means (42, 98) of securing the anchor to the permanent implant is also included.
Patent JP-H0639256-B2 (JP)
IPC: B62D5/07
Filed: 1984-08-11
Abstract: A closed center, load sensing hydraulic system is disclosed which contains a primary work circuit which has priority in flow demand over a secondary work circuit. The system includes a variable displacement pump fluidly connected between a reservoir and a control valve with the primary work circuit. The primary work circuit includes a control valve which regulates fluid flow from the pump to a primary hydraulic function and which includes a feedback mechanism connected thereto. The secondary work circuit also includes a manually operable control valve for regulating fluid flow from the pump to a secondary hydraulic function. A priority valve is connected between the pump and the secondary work circuit and movable between an open and a closed position to regulate the pressure of fluid discharged by the pump. Pressurized fluid from the primary work circuit is conveyed through a load signal line to the priority valve such that the pressurized fluid will urge the priority valve towards a closed position thereby assuring that adequate fluid pressure is available from the pump to the primary work circuit. The system also includes a control valve for sensing pressure variations between the fluid discharged from the pump and fluid present in the load signal line. This valve controls fluid flow out of the primary hydraulic function, via the load signal line, when the pressure of the fluid discharged by the pump is less than the pressure of the fluid in the load signal line and thereby essentially eliminates kickback from the primary control valve.
Patent JP-S5916452-B2 (JP)
IPC: H04L12/413
Filed: 1981-11-05
Abstract: PURPOSE:To improve the reliability of the system and to perform signal transmission in high speed with a very simple constitution, by constitution of one optical fiber folded into two as U-shape, and of an optical passive circuit consisting of only photocouplers using a half mirror. CONSTITUTION:An optical fiber cable 5 is folded as almost U-shape to form a transmission line, and incoming/outgoing lines 6, 7 are respectively formed with the cable 5 and an optical relay device 8 is inserted to the lines. In transmitting data, e.g., from a terminal 14-1 to a terminal 14-3, a signal is converted into an optical signal at a node 11-1 and transmitted to a fiber cable 12-1, a photocoupler 9-1, the relay device 8, a folding section 5c, and a photocoupler 10-3. The signal is transmitted from the terminal 14-3 to the terminal 14-1 via a photocoupler 9-3, the relay device 8, a photocoupler 10-1, a fiber cable 13-1, and the node 11-1. In both the cases, the transmitted data includes an address and  the data can be transmitted to the terminal of the desired node.
Patent JP-4298814-B2 (JP)
IPC: C12Q1/686
Filed: 1998-06-24
Granted: 2009-07-22
Abstract: The present invention relates to nucleic acid primers and probes specific for organisms of the Mycobacterium avium complex (MAC) and to their use in nucleic acid amplification methods for the detection and differentiation of such organisms in biological samples. The invention also relates to diagnostic kits for detecting and differentiating the various organisms comprising the MAC.
Patent JP-H0117044-B2 (JP)
IPC: F27B15/00
Filed: 1981-11-06
Abstract: 1. Method for cooling of the ash which, through overflow tubes, is discharged from a fluidized bed combustor into an ash cooler provided with distributor plate and heat-exchange surfaces characterized by the ash which on load reduction in the fluidized bed combustor is fluidized by a fluidizing agent supplied and in case of continuous operation of the fluidized bed combustor on disconnection of the fluidizing agent supply is distributed in bulk over the heat-exchange surfaces.
Patent JP-2750023-B2 (JP)
IPC: A61B5/0452
Filed: 1991-07-18
Granted: 1998-05-13
Abstract: A device with sensor means (13), which are arranged removably on the outside of a body and are connected to electronic circuit means (43), serves for the continuous measurement of the blood pressure and a correlated variable, in particular the flow velocity of the arterial blood, and for the determination of the pulse rate. The sensor and circuit means (13, 43) moreover determine a variable, which is a measure of the pulse rate, and calculate, by combining the two variables and including at least one calibration value, at least one variable characteristic of the blood pressure, namely the systolic blood pressure. 
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Patent JP-2749247-B2 (JP)
IPC: A61K9/48
Filed: 1993-07-28
Granted: 1998-05-13
Abstract: The use of raloxifene, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for preventing or treating osteoporosis in a postmenopausal woman.
Patent JP-3054738-B2 (JP)
IPC: A61K31/55
Filed: 1989-07-19
Granted: 2000-06-19
Abstract: New thiazolo [5,4-b]azepine compounds represented by <CHEM> ,wherein R<1> is a hydrogen atom, an aliphatic group which may be substituted, a carboxylic acyl group which may be substituted or a sulfonic acyl group which may be substituted; R<2> is a hydrogen atom, an aromatic group which may be substituted or an aliphatic group which may be substituted, which are capable of e.g., inhibiting lipoperoxide formation.
Patent JP-3385042-B2 (JP)
IPC: B01F23/00
Filed: 1992-07-30
Granted: 2003-03-10
Abstract: The device for mixing in a small amount of fluid (1) into the main stream of another fluid (2) in a main duct has a nozzle injection system (3) and a static mixing element (4, 5) downstream thereof. The input cross section (F) of the mixing element is subdivided into subareas (F1, F2, F3, F4). The nozzle injection system comprises metering main pipes having a plurality of directed metering orifices (21). The flow rates through the metering orifices are proportional to the part streams through the corresponding associated subareas (F1, F2, F3, F4). This results in very uniform through-mixing over a short distance and with only a small pressure drop. The mixing-in device is particularly suitable for Denox installations. <IMAGE>
Patent JP-2785018-B2 (JP)
IPC: C01F17/235
Filed: 1988-08-19
Granted: 1998-08-13
Abstract: A process is provided for preparing colloidal dispersions of alcohol-dispersible association complexes of ceric dioxide and a hydroxyphenyl carboxylic acid having from about seven to about twenty carbon atoms in a molar ratio CeO2/acid of at least about 6:1 which comprises: (1) mixing (a) ceric dioxide comprising ammonium nitrate or ammonium and nitrate ions in an amount within the range from about 3 to about 14% by weight of the ceric dioxide and a member selected from the group consisting of water, methanol, acetic acid and mixtures thereof in an amount usually from about 10 to about 60 g per mole of CeO2, sufficient to effect reaction with (b) a hydroxyphenyl carboxylic acid having from about seven to about twenty carbon atoms (c) an aliphatic alcohol, such as methanol, isopropanol, 2-ethoxy ethanol, etc. at a temperature within the range from room temperature to about 100 DEG  C., thereby effecting dispersion of the ceric dioxide in the aliphatic alcohol.
Patent JP-2761987-B2 (JP)
IPC: G04B37/00
Filed: 1991-06-07
Granted: 1998-06-04
Abstract: The middle of the watch (1) is provided with two lateral protuberances (2, 3) each having a groove (4, 5) intended to receive the pin (6) of a piece of bracelet (7). On the middle (1) is mounted a ring (8) by means similar to that of a rotary rim. The rotary rim (8) is also provided with two lateral protuberances (9, 10) whose shape is complementary to that of the protuberances (2, 3) of the middle (1) in order to lock, and unlock the extremities of the bracelet.
Patent JP-3080957-B2 (JP)
IPC: C23C14/56
Filed: 1988-09-19
Granted: 2000-08-28
Abstract: An apparatus for coating substrates in a vacuum chamber has a cathode system, which is preceded and followed by evacuable isolating chambers. The individual chambers can be separated from one another by locks, and the apparatus has a conduit leading into the coating chamber for feeding one or more process gases. Transport frames carry the substrates through the individual chambers on rails and/or wheels. In such an apparatus one or more bypass lines are provided which connect the coating chamber to the isolating chambers preceding or following it, and a shutoff or valve is inserted into each bypass line and brings about an equalization of pressure between the chambers. By means of a pressure equalization performed in this manner, the constancy of the gas concentrations which is essential in a reactive process to the stability of the process and to uniform coating properties, is automatically assured.
Patent JP-H089700-B2 (JP)
IPC: C09D201/00
Filed: 1986-10-02
Abstract: Lacquers and molding compositions containing an anti-adhesive character producing and lubricity increasing amount of a polyester-containing polysiloxane corresponding to the formula <IMAGE>  (I)  wherein A, B and D each represent -CH3 or -Z-R-Q; Z represents an alkylene group with 1 to 11 carbon atoms, -(CH2)2SCH2-or -(CH2)3NHCO-; R represents an aliphatic, cycloaliphatic or aromatic group containing at least 3 carboxylate ester groups and having an average molecular weight  &upbar& M of 300 to 3,000; Q represents a reactive group capable of chemically reacting with a resin component of the lacquer or molding composition; x represents a number from 4 to 150; y represents a number from 1 to 6, in which an average molecule contains at least one group -Z-R-Q and the ratio of the number of -Z-R-Q groups to the number x is from 1:3 to 1:30. A process for imparting anti-adhesive character and increasing lubricity of lacquers and molding compositions by incorporating such polyester-containing polysiloxanes into the compositions as additives is also disclosed.
Patent JP-4763111-B2 (JP)
IPC: B01D45/14
Filed: 1999-09-01
Granted: 2011-08-31
Abstract: The blades (3) are tapered, with their outer edges defining a cylinder and their inner edges defining a cone. The broad edges of the blades are fastened to a solid disc (2) mounted on a hub (1) attached to a drive shaft. The narrow edges of the blades are attached to a ring (4) whose width is equal to the width of the narrow ends of the blades.
Patent JP-H0583992-B2 (JP)
IPC: B65H19/12
Filed: 1990-09-26
Abstract: In a cassette loading machine several loading modules (4) carry out the loading of a predetermined amount of use tape (8) into the individual cassettes (3), said tape being continuously supplied from a pancake (9) mounted on a support hub (10). When one of the pancakes (9) mounted on one of the hubs (10) is out of tape (8), the intervention of a manipulating unit (48) occurs and said unit picks up, by means of a grasping and release member (59) carried by a supply module (55), a new pancake (9) filled with use tape (8) from a storage unit (14) located sideways. The manipulating unit (48) moves close to the out of tape pancake (9) and removes it from the respective support hub (10) with the aid of a grasping member (59) carried by a discharge module (54). Then the new pancake (9) filled with use tape is mounted onto the support hub (10) in place of the out of tape pancake (9). <IMAGE>
Patent JP-H0768598-B2 (JP)
IPC: C22C14/00
Filed: 1987-10-23
Abstract: A titanium-base alloy having good elevated temperature properties, particularly creep resistance in the 950 to ll00 DEG F (5l0 to 593 DEG C) temperature range. The alloy consists of, in weight percent, aluminium 5.5 to 6.5, tin 2.00 to 4.00, preferably 2.25 to 3.25, zirconium 3.5 to 4.5, molybdenum .3 to .5, silicon above .35 to .55, iron less than .03, oxygen up to .l4, preferably up to .09 and balance titanium.