baber/WOPTO huggingface dataset:
Patent CA-2471661-A1 (CA)
Inventor: JOHNSON KORY
IPC: C12Q1/68
Filed: 2003-01-31
Abstract: L'invention concerne l'élucidation de changements globaux affectant l'expression génique et l'identification de marqueurs de toxicité dans des tissus ou des cellules hépatiques exposés à une toxine connue. Les gènes peuvent être utilisés en tant que marqueurs de toxicité dans le criblage de principe actif et dans des tests de toxicité. L'invention concerne aussi une base de données de gènes, caractérisés par l'expression hépatique différentielle induite par toxine, conçue pour être utilisée avec des micromatrices et d'autres sondes en phase solide.
Patent CA-2474411-A1 (CA)
Inventor: LUTHRA SAJINDER KAUR
IPC: A61K49/00
Filed: 2003-02-12
Abstract: La présente invention concerne l'utilisation d'un composé représenté par la formule (I) ou un sel de ce dernier. Dans la formule, R1 représente 125I, 124I, 123I, 75Br, 76Br, ou 18F; R2 représente alkyle C1-6; et R3 est sélectionné parmi hydrogène, alkyle C1-6, -C(O) alkyle C1-.6, -C(O) haloalkyle C1-6, et -C(O)CH(R4)NH2; R4 étant sélectionné entre hydrogène, alkyle C1-6, hydroxyalkyle C1-6, et aminoalkyle C1-6. On utilise ce composé pour préparer un radiopharmaceutique employé dans le diagnostic ou l'imagerie in vivo de la maladie associée aux plaques amyloïdes, notamment la maladie d'Alzheimer. Formule (I)
Patent CA-2478405-A1 (CA)
Title: Dishwasher unit dose detergent dispenser
Inventor: WIEDEMANN RALF
IPC: D06F39/02
Filed: 2003-03-05
Abstract: The present invention is directed to a device for receiving and holding a plurality of unit doses (2) of a detergent composition and/or additive and for individually dispensing said unit doses into an automatic dishwashing machine over a plurality of washing cycles, wherein the device comprises (i) a housing (10) adapted to receive said plurality of unit doses (2) each separately contained in a package or compartment (4) thereof, (ii) means (15, 16, 17, 18, 19) for opening said package or compartment or for at least partly ejecting said unit dose (2) therefrom; and (iii) means (20, 21, 27, 28) to allow access of water or wash liquor to said unit doses (2) contained in the opened package or compartment (4) or ejected therefrom within a controlled time period after opening thereof to allow dissolution of the unit dose (2) into the water or wash liquor of the machine, as well as to a blister pack (1) for use therewith.
Patent CA-2481019-A1 (CA)
Inventor: HALVARSSON PER
IPC: H01T2/02
Filed: 2003-05-08
Abstract: L'invention concerne un dispositif permettant de fermer rapidement un circuit électrique haute tension. Ce dispositif comprend un éclateur (1) équipé de première (2) et de seconde (3) électrodes et un dispositif de déclenchement (10) Le dispositif de déclenchement comprend un éclateur auxiliaire (4) équipé de première (5) et de seconde (6) électrodes auxiliaires, conçu, si nécessaire, afin de produire un arc (a) dans l'éclateur auxiliaire (4) afin d'amorcer un arc (A) dans l'éclateur principal (1). Selon cette invention, chaque électrode auxiliaire (5, 6) est équipée d'un rail guide (13, 14) conçu de telle façon que l'arc, via les rails guide, et tout en étant influencé par le champ magnétique, se déplace dans l'éclateur principal (1). La longueur des rails guide est plus importante que la largeur de l'éclateur auxiliaire (4). Les électrodes auxiliaires (5, 6) sont agencées de façon à être protégées de l'effet de plasma formé dans l'éclateur principal. Les éclateurs sont disposés dans une enceinte hermétique. L'invention concerne aussi un procédé et une utilisation.
Patent CA-2481836-A1 (CA)
Title: Apparatus for drying dip-coated medicaments
Inventor: HOOVER LINN
IPC: B65G47/248
Filed: 1998-07-01
Abstract: The invention is directed an apparatus for drying a plurality of dip-coated medicaments, said apparatus comprising an air plenum having at least one air directing plate, said at least one air directing plate having at least one row of air directing apertures arranged in a sinusoidal layout; an air source for providing air to said at least one air directing plate; and a dryer conveyer system for transporting said medicaments under said air plenum in a product flow direction.
Patent CA-2483167-A1 (CA)
Inventor: HEIMAN GARY L
IPC: D03D27/08
Filed: 2004-09-29
Abstract: A woven terry fabric (10) includes a non-moisture-transporting synthetic filament yarn (F) in at least one of the fill or the warp. The pile loops (T) comprise natural fibers. The fill yarn, warp yarn, and pile loop yarn are woven together in a three-pick terry-weave pattern.
Patent CA-2483884-A1 (CA)
Title: Piston-type flushometer with inner cover
Inventor: NORTIER RICHARD A
IPC: E03D3/04
Filed: 2004-10-06
Abstract: A flush valve includes a body having an inlet and an outlet. There is a main seat assembly at the outlet. An outer cover is attached to the body and an inner cover is attached to the body within the outer cover. A piston is movable within the body and inner cover and, with the inner cover, defines a pressure chamber. The piston carries an exterior seal which bears against an inside wall of the inner cover during movement of the piston. A  refill orifice in the piston connects the chamber with the body inlet. Pressure in the chamber maintains the piston closed upon the main seat assembly. A relief valve is positioned in the piston for venting the chamber to the outlet. When the relief valve is opened and the chamber is vented, the piston moves away from the main seat assembly connecting the inlet with the outlet.
Patent CA-2484891-A1 (CA)
Title: Conjugates comprising central nervous system active drug
Inventor: RAMANATHAN HALASYA
IPC: A61K47/48
Filed: 2003-05-07
Abstract: Disclosed are conjugates comprising a central nervous system-active drug linked through an amide bond to a glucuronic acid or glucosamine moiety, and uses thereof, e.g., for treating or ameliorating central nervous system diseases or disorders.
Patent CA-2485587-A1 (CA)
Title: Muteins of placental growth factor type 1, preparation method and application thereof
Inventor: SALVIA GIUSEPPE
IPC: C12N15/18
Filed: 2003-05-19
Abstract: The present invention relates to chemically stable muteins of type 1 Placent al Growth Factor (PLGF-1) bearing the substitution or elimination of a cysteine residue from the wild type protein amino acid sequence, their preparation, their therapeutic and cosmetic uses, and pharmaceutical and cosmetic compositions containing said derivatives. The invention likewise relates to the production of antibodies for said derivatives and their use in the diagnosis and treatment of tumoral and non-tumoral pathologies.
Patent CA-2489809-A1 (CA)
Title: Active substance controlled release devices and process for producing the same
Inventor: CREMER KARSTEN
IPC: A61K9/70
Filed: 1995-05-08
Abstract: A process for the production of devices for the controlled release of active substances, consisting of an active substance-containing matrix and an erodible mass of solids at least partially covering the matrix, with the thickness of the erodible mass across its extension being determined by thickness gradients, and the active substance-containing matrix itself being produced with thickness gradients which determine the thickness gradients of the erodible mass, is characterized in that in a first step the active substance-containing matrix is formed in the form of pressed articles having thickness gradients, and in a second step it is transferred onto a laminated tablet-compressing machine where it is compressed with the erodible mass.
Patent CA-2492839-A1 (CA)
Title: Plasticized polyolefin compositions
Inventor: YANG HENRY WU-HSIANG
IPC: C08K5/01
Filed: 2003-08-04
Abstract: The present invention relates to plasticized polyolefin compositions comprising a polyolefin and a non-functionalized plasticizer; wherein the no n- functionalized plasticizer may comprise C6 to C200 paraffins (including branched and normal paraffins) having a pour point of less than -5 ~C. In on e embodiment, the non-functionalized plasticizer is an isoparaffin comprising C6 to C25 isoparaffins. In another embodiment the non-functionalized plasticize r is a polyalphaolefin compising C10 to C100 n-paraffins. The polyolefin may b e a polypropylene homopolymer, copolymer, impact copolymer, or blends thereof, and may include a plastomer. Non-limiting examples of desirable article of manufacture made from compositions of the invention includes films, tubes, pipes, sheets, fibers, woven and nonwoven fabrics, automotive components, furniture, sporting equipment, food storage containers, transparent and semi - transparent articles, toys, tubing and pipes, and medical devices.
Patent CA-2494740-A1 (CA)
Inventor: FOSTER ALAN
IPC: B60B33/00
Filed: 2003-08-26
Abstract: A support structure for a castor, a castor provided with such a support- structure, and a castored trolley is described. The support structure comprises a first member 5, a second member 3 that is rotatable with respect to the first member about a pivot axis, and magnetic means 21, 23, 61, 63 th at is operable up to a certain torque to restrain movement of the rotatable member from one angular position with respect to the first member. Preferabl y the magnetic means comprises at least one hair of magnetically co~-operable components. Preferably one component of the at least one pair of components is a permanent magnet. In another angular positions without registration of the first and second members free rotation is possible unless and until re- registration occurs.
Patent CA-2495106-A1 (CA)
Title: Hand-held inventory tracking and automated order transmission system
Inventor: DUIS DONNIE
IPC: G06Q10/00
Filed: 2002-08-15
Abstract: A dynamic inventory tracking and management system and methodology therefore that streamlines the inventory level tracking process of contact lens products for prescriptive and diagnostic purposes maintained at various locations having eye care practitioners responsible for dispensing lenses to patients.  The system inventory tracking system seamlessly interfaces with order entry infrastructure to automatically initiate replenishment of stock and diagnostic lens inventory levels maintained at various eye care practitioner locations, and/or provide low inventory warning messages for receipt by the ECP.
Patent CA-2495703-A1 (CA)
Inventor: LINGLE PHILIP J
IPC: C03C17/36
Filed: 2003-08-20
Abstract: A sputter coated article is provided with improved mechanical durability (e.g., pre-HT scratch resistance) and/or thermal stability by sputtering at least one Ag inclusive layer in an atmosphere including at least O2 gas. For instance, in certain example embodiments an Ag inclusive target may be sputtered in an atmosphere including a combination of Ar and O2 gas. In certain embodiments, this enables the resulting AgOX infrared (IR) reflectin g layer to better adhere to adjacent contact layer(s).
Patent CA-2497178-A1 (CA)
Title: A method and a system for performing connectivity evaluations on data communication networks and related information technology product
Inventor: CORRADO ALESSANDRO
IPC: H04L12/715
Filed: 2003-09-01
Abstract: For the benefit of a reference ISP (10) having a number of users (C), connectivity evaluations on a data communication network are performed in relation to one or more ISPs of interest (12, 14). Upon selecting a plurality (T) of autonomous systems (AS) capable of forming a traffic source and/or destination for the users (C) of the reference provider (10), tables of the BGP type (BGP1, ..., BGPm) are provided containing information on the paths available on the network for routing the traffic with regard to the above-mentioned autonomous systems (AS). From said tables the paths of BGP type are extracted relating to the provider or providers of interest (12, 14), searching for the paths that contain the respective AS number for the provider and/or providers of interest (12, 14). For each autonomous system (AS) the oriented sub-paths are extracted between each said autonomous system (AS) and the provider or providers of interest (12, 14), identifying for each sub-path the relating number of hops.
Patent CA-2499681-A1 (CA)
Inventor: CHENG WOEI PING
IPC: C08G73/02
Filed: 2003-09-22
Abstract: This invention relates to the delivery of drugs. In particular, this inventi on relates to the oral delivery of poorly soluble drugs using novel amphiphilic polymers with both solubilising and absorption enhancing properties.
Patent CA-2499957-A1 (CA)
Title: Fuel cell system and method of operation to reduce parasitic load of fuel cell peripherals
Inventor: SIMPSON TODD A
IPC: H01M8/04
Filed: 2003-09-23
Abstract: A fuel cell system and a method of operating same are provided. The fuel cel l system includes a fuel cell for driving a load, at least one fuel cell peripheral, a device for measuring at least one fuel cell operation characteristic, and at least one controller for controlling the operation of at least one fuel cell peripheral based on the at least one fuel cell operation characteristic. The fuel cell operation characteristic is divided into at least two ranges, and operation of at least one fuel cell is controlled to provide it with a respective operational characteristic for ea ch range of operation of the fuel cell system.
Patent CA-2500135-A1 (CA)
Title: Membrane bioreactor waste water treatment method
Inventor: LANGLAIS CHRYSTELLE
IPC: C02F11/14
Filed: 2003-09-23
Abstract: The invention relates to a membrane bioreactor (1) waste water treatment method comprising a sludge dewatering step (4) and a step involving the recycling (6, 7) of the liquid effluent originating from the sludge dewatering step, which is performed at the head of the bioreactor. The invention is characterised in that: the biological sludge extracted from the bioreactor (1) is brought into contact in a contactor (2) with the liquid effluent (6) from the sludge-dewatering step such that the residual polyelectrolyte content in said effluent, which was used for sludge conditioning during the dewatering step (4), moves towards the biological sludge; the biological sludge originating from the contactor (2) is separated from the liquid effluent such as to produce a polyelectrolyte-free liquid effluent (7) and a polyelectrolyte-loaded biological sludge (5); the polyelectrolyte-free liquid effluent (7) is recycled at the head of the membrane bioreactor (1); and the polyelectrolyte-loaded biological sludge (5) is conveyed towards the dewatering step (4).
Patent CA-2501326-A1 (CA)
Title: Improved conversion of sodium bromide to anhydrous hydrobromic acid and sodium bisulfate
Inventor: KENNEALLY COREY JAMES
IPC: C01D5/02
Filed: 2003-09-20
Abstract: Process for the conversion of sodium bromide to anhydrous hydrobromic acid and sodium bisulfate, said process with the following sequential steps: reaction of sodium bromide and sulfuric acid in a solution of water to produce hydrobromic acid and sodium bisulfate wherein the conversion of sodium bromide is greater than about 99%; adsorption of iron bromide onto a solid adsorbent;  separation of hydrobromic acid and water from the sodium bisulfate; separation and drying of hydrobromic acid; and solidification of the sodium bisulfate into a flaked or granular form.
Patent CA-2501732-A1 (CA)
Inventor: PACIONE CHRISTOPHER
IPC: G16H40/63
Filed: 2003-10-09
Abstract: Various methods and apparatuses for measuring a state parameter of an individual using signals based on one or more sensors are disclosed. In one embodiment, a first set of signals (1600) is used in a first function to determine how a second set of signals is used in one or more second functions to predict the state parameter (1620). In another embodiment, first and second functions (1610) are used where the state parameter or an indicator of the state parameter may be obtained from a relationship between the first function and the second function. The state parameter may, for example, include calories consumed or calories burned by the individual. Various methods for making such apparatuses are also disclosed.
Patent CA-2505295-A1 (CA)
Inventor: STROM CLIFFORD P
IPC: G10K15/02
Filed: 2005-04-22
Abstract: Metered data is accumulated and is indexed within a metering database of a client according to a metering ID (MID) and a content-associated TD (KID). The client selects a particular MID and metered data in the metering database having the selected MID, and constructs a challenge based on the selected metered data and sends same to a metering service. The metering service obtains the metered data from the challenge, stores same, and constructs a response. The client receives the response including a list of KIDS of the selected metered data in the challenge, and processes the list of KIDs by, for each KID in the list, deleting the metered data from the metering database having the selected MID and the KID.
Patent CA-2505498-A1 (CA)
Title: Fungicidal mixtures for controlling rice pathogens
Inventor: SCHOEFL ULRICH
IPC: A01N43/90
Filed: 2003-11-14
Abstract: The invention relates to fungicidal mixtures for controlling rice pathogens, said mixtures containing 1) the compound of formula (I), and 2) the compound of formula (II), as active constituents in a synergistically effective quantity. The invention also relates to methods for controlling pathogenic fungi using mixtures containing compound (I) and compound (II), to the use of compounds (I) and (II) for producing such mixtures, and to agents containing said mixtures.
Patent CA-2505610-A1 (CA)
Inventor: KAHLE JAMES ALLAN
IPC: G06F12/10
Filed: 2003-11-21
Abstract: Memory management in a computer system is improved by preventing a subset of address translation information from being replaced with other types of address translation information in a cache memory reserved for storing such address translation information for faster access by a CPU. This way, the CPU  can identify the subset of address translation information stored in the cache.
Patent CA-2506177-A1 (CA)
Title: Rectifier-super capacitor device for use in a power system for a telecommunication facility
Inventor: JOHNSON LARRY L
IPC: H02J9/06
Filed: 2003-11-13
Abstract: The present invention is a device (480) that includes a rectifier (490) and a super capacitor (500) packaged together in a single housing. The device has a first connection point (520) that is coupled to the rectifier input. The output of the rectifier is coupled to a first side of the capacitor and to a second connection point (540) of the device. The second side of the capacito r is coupled to ground through a third connection point (570). The device is operable to receive AC power and provide DC power. Moreover, through the operation of the super capacitor, the device will provide DC power for a tim e after AC power has been removed.
Patent CA-2515143-A1 (CA)
Title: Comfortable diaper
Inventor: MAIER VOLKER
IPC: A61F13/15
Filed: 2004-02-12
Abstract: The present invention concerns an absorbent article (20), preferably a disposable absorbent article, such as a diaper. The present invention specifically concerns an absorbent core (28) for such an absorbent article which provides an improved immobilization of absorbent polymer material when the article is fully or partially urine loaded. This absorbent core is useful for providing an absorbent article of increased wearing comfort. Specifically disclosed is an absorbent core useful for an absorbent article comprising a substrate layer and absorbent material, the absorbent material comprising an absorbent polymer material, the absorbent material optionally comprising absorbent fibrous material, the absorbent fibrous material not representing more than 20 % of the weight of absorbent polymer material, wherein the absorbent material is immobilized when wet such that the absorbent core achieves a wet immobilization of more than 50%, preferably of more than 60 %, 70 %, 80 % or 90 % according to the Wet Immobilization Test described herein.
Patent CA-2517264-A1 (CA)
Inventor: WILSON JULIE ANN
IPC: C07K14/18
Filed: 2004-03-09
Abstract: Using CTL epitopes to the Ebola GP, NP, VP24, VP30, VP35 and VP40 virion proteins, a method and composition for use in inducing an immune response which is protective against infection with Ebola virus is described.
Patent CA-2517295-A1 (CA)
Title: Generation of dendritic cells from monocytic dendritic precursor cells with gm-csf in the absence of additional cytokines
Inventor: BOSCH MARNIX L
IPC: C12N5/02
Filed: 2004-02-27
Abstract: The present invention it was determined that dendritic cells could be derived from various sources including peripheral blood monocytes in the presence of only GM-CSF without other cytokines if the monocytes were not activated. By preventing activation, such as by preventing binding of the cells to the surface of the culture vessel, the monocytes do not require the presence of additional cytokines, such as IL-4 or IL-13, to prevent differentiation into a non-dendritic cell lineage. The immature DCs generated and maintained in this manner were CD14- and expressed high levels of CD1a. Upon maturation by contact with an agent such as, for example, BCG and IFN.gamma., the cells were determined to express surface molecules typical of mature dendritic cells purified by prior methods and cultured in the presence of GM-CSF and IL-4. The mature dendritic cells produced from monoxytes without activation and cultured in GM-CSF alone are suitable for use in dendritic cell-based immunotherapy methods, such as for use in the treatment of disease, including cancer.
Patent CA-2517754-A1 (CA)
Title: Two-cone drill bit
Inventor: CENTALA PRABHAKARAN K
IPC: B21K5/02
Filed: 2005-08-31
Abstract: A two-cone drill bit with a hydraulic arrangement that can be used for one or more of the following: cleaning roller cones, impinging on a hole bottom, or inducing a helical flow field. A two-cone drill bit having a bit body formed from two leg sections and two spacing members. Methods of manufacturing a two-cone drill bit. Methods of improving hydraulics of a two-cone drill bit.
Patent CA-2519763-A1 (CA)
Title: Improved composition and method for removal of carbonyl sulfide from acid gas containing same
Inventor: ASHCRAFT ARNOLD C
IPC: B01D53/48
Filed: 2004-03-11
Abstract: Novel solvent composition for selective removal of COS from a gas stream containing same, said composition comprising a) at least one polyalkylene glycol alkyl ether of the formula (I) or 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone or a mixture of N-formylmorpholine and N-acetylmorpholine Wherein R1 is an alkyl group having from 1 to 6 carbon atoms; R2 is hydrogen or an alkyl group having from 1 to 4 carbon atoms; Alk is an alkylene group, branced or unbranced, having from 2 to 4 carbon atoms, and n is from 1 to 10; and b) at least one alkanolamine compound of the formula (II) or at least one piperazine compound of formula (III) wherein R3 is hydrogen, an alkyl group having from 1 to 6 carbon atoms, or the R4OH group; R4 is a branched or unbranched alkylene group having from 1 to 6 carbon atoms; R5, independently in each occurrence, is hydrogen or an hydroxyalkyl group having from 1 to 4 carbon atoms; and R6 is hydrogen, an alkyl group having from 1 to 6 carbon atoms or an hydroxyalkyl group having from 1 to 4 carbon atoms. ~
Patent CA-2522029-A1 (CA)
Title: A flexible, super durable powder coating composition
Inventor: DOVE HOMER H
IPC: C09D5/03
Filed: 2005-10-04
Abstract: Powder coatings having good impact resistance and weatherability characteristics are produced with an isophthalic acid-based polyester and an isocyanate-based curing agent.
Patent CA-2525452-A1 (CA)
Inventor: JARVEST RICHARD LEWIS
IPC: A61K31/7048
Filed: 2004-05-11
Abstract: The present invention relates to 14- or 15-membered macrolides substituted at the 4" position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infections in a human or animal body.