Patent SG-11201909915P-A (SG)
Title: Electrosurgical instrument for performing ablation or electroporation of biological tissue
Inventor: HANCOCK CHRISTOPHER PAUL
IPC: A61B18/18
Filed: 2018-06-01
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 13 December 2018 (13.12.2018) WIP01 PCT o mot oIIl ono oIIIomDIDHoHoIIIIIIIII111110mOIIIIII (10) International Publication Number WO 2018/224404 Al (51) International Patent Classification: A61B 18/18 (2006.01) A61B 18/00 (2006.01) A61N 1/32 (2006.01) A61B 18/12 (2006.01) A61B 18/14 (2006.01) (21) International Application Number: PCT/EP2018/064467 (22) International Filing Date: 01 June 2018 (01.06.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1709134.9 08 June 2017 (08.06.2017) GB (71) Applicant: CREO MEDICAL LIMITED [GB/GB]; Creo House Unit 2, Beaufort Park, Beaufort Park Way, Chep- stow, Monmouthshire NP16 5UH (GB). (72) Inventors: HANCOCK, Christopher Paul; 37 Napier Road, Bath, Bath and North East Somerset BA1 4LN (GB). BISHOP, John; c/o Creo Medical Limited, Creo House Unit 2, Beaufort Park, Beaufort Park Way, Chepstow, Mon- mouthshire NP16 5UH (GB). (74) Agent: JOHNSON, Richard et al.; Mewburn Ellis LLP, City Tower, 40 Basinghall Street, London, Greater London EC2V 5DE (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: — with international search report (Art. 21(3)) = (54) Title: ELECTROSURGICAL INSTRUMENT FOR PERFORMING ABLATION OR ELECTROPORATION OF BIOLOGICAL TISSUE 208 214 202 206 204 212 222 (7 ,4 216 210 220 218 200 FIG. 3 00 O 0 (57) : An electrosurgical instrument capable of performing both thermal ablation and electroporation in a minimally invasive manner. The instrument is dimensioned to fit within an instrument channel of an endoscope to enable non-percutaneous insertion. The instrument comprises a radiating tip mounted at a distal end of a coaxial transmission line to receive microwave EM energy from the coaxial transmission line and emit it as a field around the radiating tip. The instrument further comprises an auxiliary transmission line arranged to convey electromagnetic energy having an electroporation waveform to a microelectrode array mounted on the radiating tip. The electroporation waveform may be a radiofrequency or low frequency electromagnetic (EM) signal. The microelectrode array may comprise a plurality of nanoscale conductive electrode elements.