baber/WOPTO huggingface dataset:
Patent AU-2003204353-B2 (AU)
Title: Methods and compositions for enhancing immune response and for the production of in vitro mabs
Inventor: PACIOTTI GIULIO F
IPC: A61K47/48
Filed: 2003-05-23
Granted: 2006-08-10
Abstract: The methods and compositions of the present invention are directed to enhancing an immune response and increasing vaccine efficacy through the simultaneous or sequential targeting of specific immune system components. More particularly, specific immune components, such as macrophages, dentritic cells, B cells and T cells, are individually activated by component-specific immunostimulating agents. One such component-specific immunostimulating agent is an antigen-specific, species-specific monoclonal antibody. The invention is also directed to a method for the in vitro production of the antigen-specific, species-specific monoclonal antibodies which relies upon the in vitro conversion of blood-borne immune cells, such as macrophages and lymphocytes. Vaccine efficacy is enhanced by the administration of compositions containing component-specific immunostimulating agents and other elements, such as antigens or carrier particles, such as colloidal methods, such as gold.
Patent AU-2003212064-B2 (AU)
Title: Screening for blood coagulation defects using metal ions
Inventor: ROSEN BERT STEFFEN
IPC: C12Q1/56
Filed: 2003-07-03
Granted: 2005-10-20
Abstract: In vitro photometric method for qualitative screening and quantitative determination of the functional activity of components of the Protein C anti-coagulant pathway of blood coagulation, comprising measuring the conversion rate of an exogenous substrate by an enzyme, the activity of which is related to the Protein C anticoagulant activity, in a blood sample of a human comprising coagulation factors and said exogenous substrate after at least partial activation of coagulation through the intrinsic, extrinsic or common pathway and triggering coagulation by adding calcium ions; and comparing said conversion rate with the conversion rate of a normal human blood sample determined in the same way, comprising adding further metal(s) ions to said sample; kits and reagents for use in said method. <IMAGE>
Patent AU-2003257705-B2 (AU)
Title: Toy gun
Inventor: KUNIMOTO KEIICHI
IPC: F41B11/721
Filed: 2003-10-24
Granted: 2005-04-21
Abstract: The toy gun has a gas flow control mechanism (50) movably arranged with respect to a movable portion (10) to form a first gas passage (51) for guiding gas into a loading chamber (4), and a second gas passage (52) for guiding gas to pressure receiving portions (14,22). The gas flow control mechanism makes preparations in supplying bullet (P) from a magazine (5) to the loading chamber. The gas flow control mechanism transfers from first state to second state for a period, in which the gas supply controllers (8,8',36,38,39) take the gas supply state as the movable portion moves in the first direction, for moving the movable component in a second direction to make preparations for supplying bullet from magazine to loading chamber. When in first state, the first gas passage is opened and the second gas passage is closed to supply the gas obtained in a gas outlet passage (34) to the loading chamber through the first gas passage. When in second state, the first gas passage is closed and the second gas passage is opened to apply the gas obtained in the gas outlet passage to the pressure receiving portions through the second gas passage.
Patent AU-2004255470-B2 (AU)
Title: Packaged virus-like particles
Inventor: BACHMANN MARTIN F
IPC: C07K14/08
Filed: 2004-07-12
Granted: 2010-08-19
Abstract: The present invention is related to the fields of vaccinology, immunology and medicine. The invention provides compositions and methods for enhancing immunological responses against antigens coupled or fused to virus-like particles (VLPs) packaged with immunostimulatory nucleic acids, preferably oligonucleotides containing at least one non-methylated CpG sequence and a toll-like receptor (TLR) ligand. The invention can be used to induce strong antibody and T cell responses particularly useful for the treatment of allergies, tumors and chronic viral diseases as well as other chronic diseases.
Patent AU-2005217461-B2 (AU)
Title: Encoding and Decoding Alphanumeric Data
Inventor: HO MAK MICHAEL MAN
IPC: B64F1/36
Filed: 2005-03-01
Granted: 2011-07-14
Abstract: Information, such as ticket information is encoded, for transmission of the encoded information to a device that candisplay the encoded information as visible alphanumeric characters. Original information is converted into a binary format then separated into x bit binary words, where x is the same as a maximum number of bits data required by every data character in a pre-determined data character map. The binary words are formed into a sequence of characters using a data character map. Special marker characters are inserted into the sequence. The special characters demarcate the sequence into sets of characters separated by one or more special marker characters. Line feed command characters are also inserted. The encoded information is transmitted to a client device that displays it as a rectangular array of characters bounded by the special marker characters.
Patent AU-2005227289-B2 (AU)
Title: Process for cross coupling indoles
Inventor: KHODABOCUS AHMAD
IPC: C07D209/30
Filed: 2005-03-07
Granted: 2012-03-08
Abstract: The present invention provides a process for making a compound of general formula (I) wherein: R = H or C alkyl X = C-C cycloalkyl, C-C aryl or C-Calkyl; Y = heteroaryl or aryl; Z = H, HOC-, Calkyl OC-, C alkyl HNC(O)- and as described herein.
Patent AU-2005289072-B2 (AU)
Title: Nanoparticulated whey proteins
Inventor: MARTIN BEAULIEU
IPC: A23L15/00
Filed: 2005-09-28
Granted: 2011-11-17
Abstract: The present invention relates to a method for producing whey proteins in nanoparticulated form comprising the step of adjusting the pH of an aqueous solution of whey protein to from 5,6 to 6,4 or adjusting the ionic strength of the whey protein while keeping the pH constant, and subjecting the aqueous solution to a temperature of between 80° to 95°C, during a time period of from 10 seconds to 30 minutes, to obtain nanoparticulated whey protein having a particle size of less than 1 micrometer. The whey can be replaced by any other demineralized or slightly mineralized globular protein, in particular from egg, soy, cereals, oilseed or from other vegetable or animal origin. The present invention pertains to the use of these nanoparticulated whey proteins as emulsifiers, fat substitute, micellar casein substitute, whithening, foaming, texturising, filing and/or gelling agents.
Patent AU-2005291011-B2 (AU)
Title: Methods for antibody library screening
Inventor: HERALD REIERSEN
IPC: G01N33/68
Filed: 2005-10-07
Granted: 2011-10-13
Abstract: The present invention provides a method of screening a library of molecules to identify and/or select one or more members thereof which are candidate binding partners for one or more ligands comprising: a) contacting an expression library in solution with one or more ligands; b) capturing ligands which have become bound to one or more members of the expression library onto a solid phase; and c) detecting the presence of a ligand, thereby detecting the presence of one or more members of the expression library which are candidate binding partners for the ligand.
Patent AU-2005318322-B2 (AU)
Title: Method for sending an emergency call and device
Inventor: MODLER HOLGER
IPC: G08G1/123
Filed: 2005-11-18
Granted: 2010-02-18
Abstract: For sending an emergency call as a function of a predefined accident criterion, together with the emergency call, dynamic sensor data are transmitted which have been recorded in particular shortly before the occurrence of an accident criterion and which allow conclusions to be drawn about the accident situation.
Patent AU-2006247136-B2 (AU)
Title: Compositions and methods for treatment of eye disorders
Inventor: BURNIER JOHN
IPC: A61K38/08
Filed: 2006-05-17
Granted: 2012-04-19
Abstract: The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patien is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists.
Patent AU-2006247752-B2 (AU)
Title: Method and device for conducting biochemical or chemical reactions at multiple temperatures
Inventor: SHENDEROV ALEXANDER D
IPC: C12Q1/68
Filed: 2006-05-10
Granted: 2012-04-12
Abstract: Methods and devices for conducting chemical or biochemical reactions that require multiple reaction temperatures are described. The methods involve moving one or more reaction droplets or reaction volumes through various reaction zones having different temperatures on a microfluidics apparatus. The devices comprise a microfluidics apparatus comprising appropriate actuators capable of moving reaction droplets or reaction volumes through the various reaction zones.
Patent AU-2006252387-B2 (AU)
Title: Patent foramen ovale closure device
Inventor: OLSEN DANIEL
IPC: A61B17/00
Filed: 2006-06-02
Granted: 2012-03-15
Abstract: A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The deployment device has a first tubular structure having proximal and distal ends. A second tubular structure is substantially coaxial to and slideably engaged within the first tubular structure. The second tubular structure has a first substantially linear shape when constrained within the first tubular structure, and a second curvilinear shape when telescopically extended from the distal end of the first tubular structure. A third tubular structure is substantially coaxial to and slideably engaged within the second tubular structure. The third tubular structure is configured to provide sufficient rigidity to push the mechanical closure device from the distal end of the second tubular structure, and provide sufficient flexibility to assume a curvilinear shape when deflected by the second tubular structure.
Patent AU-2006252952-B2 (AU)
Title: Fabric sweeper
Inventor: MICHA MARAIA
IPC: A47L25/08
Filed: 2006-04-03
Granted: 2011-07-14
Abstract: The present invention is a device (10) for use in cleaning a fabric surface (16) of dust, dirt, pet hair and other debris (20) present on the surface (16). The device (10) includes a pair of cleaning members or rollers (60, 61) disposed on an underside of the device (10) which can roll with respect to the device (10) and with respect to one another. The rollers (60, 61) are selectively contacted with one another such that each roller (60, 61) can assist in removing debris (20) picked up by the opposite roller (60, 61) and dispensing the debris (20) into a collection chamber (32) releasably positioned within a housing (11). The removal of the debris (20) from each roller (60, 61) is also facilitated by opposed edges of a central opening (58) in the housing (11) that contact the rollers (60, 61) and direct the debris (20) into the debris collection chamber (32).
Patent AU-2006293468-B2 (AU)
Title: Heat cells comprising exothermic compositions having absorbent gelling material
Inventor: WONG VINCENT YORK-LEUNG
IPC: F24V30/00
Filed: 2006-09-22
Granted: 2012-11-15
Abstract: The present invention is directed to heat cells that are suitable for incorporation into disposable heating wraps. The heat cells comprise an exothermic composition comprising an absorbent gelling material, wherein the absorbent gelling material provides for improved heat application in the relief of temporary or chronic body aches and pains.
Patent AU-2007210377-B2 (AU)
Title: Water-soluble CC-1065 analogs and their conjugates
Inventor: DE GROOT FRANCISCUS MARINUS HENDRIKUS
IPC: C07D403/14
Filed: 2007-02-02
Granted: 2012-08-09
Abstract: This invention relates to novel analogs of the DNA-binding alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and their conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.
Patent AU-2007214011-B2 (AU)
Title: Modified coagulation factor vila with extended half-life
Inventor: SCHULTE STEFAN
IPC: C12N9/64
Filed: 2007-02-03
Granted: 2013-01-17
Abstract: The present invention relates to the fields of Factor VII (FVII) and Factor Vila (FVIIa) albumin linked polypeptides. More specifically, the invention relates to cDNA sequences coding for human Factor VII and Factor Vila and derivatives genetically fused to a cDNA coding for human serum albumin which may be linked by oligonucleotides which code for intervening peptidic linkers such encoded derivatives exhibiting improved stability and extended functional plasma half-life, recombinant expression vectors containing such cDNA sequences, host cells transformed with such recombinant expression vectors, recombinant polypeptides and derivatives which do have biological activities of the unmodified wild type protein but having improved stability and prolonged shelf-life and processes for the manufacture of such recombinant proteins and their derivatives. The invention also covers a transfer vector for use in human gene therapy, which comprises such modified DNA sequences.
Patent AU-2007258867-B2 (AU)
Title: Control method of a hybrid drive assembly for vehicles and a hybrid drive assembly using said method
Inventor: CALEO ALESSANDRO
IPC: B60L50/16
Filed: 2007-06-12
Granted: 2012-04-05
Abstract: The present invention relates to a management method of the functioning mode of a hybrid drive assembly for vehicles, in particular scooters, and a hybrid drive assembly, comprising at least one internal combustion engine and an electric machine, using the method. The method according to the invention comprises the phases of determining a desired torque and a vehicle state on the basis of a set of received input parameters and/or commands and is characterized in that it comprises the phases of operating the internal combustion engine so that it does not provide torque and operating the electric machine so, that it functions as generator for charging an accumulator, when the torque requested is negative; operating the internal combustion engine and/or the electric machine so as to satisfy the required torque, and/or bring the accumulator to a pre-established charge level and/or run the internal combustion engine under maximum efficiency regime conditions, when the torque required is positive and lower than the maximum torque which can be supplied by the internal combustion engine; and operating the internal combustion engine and/ or the electric machine with the supply of a propulsive torque so as to satisfy the torque required, when the desired torque is positive and higher than the maximum torque which can be supplied by the internal combustion engine. Furthermore, when requested by the pilot and in accordance with the charge level of the batteries, the control method switches off the internal combustion engine and drives the electric engine only so as to supply the torque requested.
Patent AU-2007280548-B2 (AU)
Title: Lubricant composition
Inventor: CHASAN DAVID ELIEZER
IPC: C10N30/00
Filed: 2007-07-23
Granted: 2012-04-05
Abstract: Certain NH sterically hindered amine compounds of the formula where R is a straight or branched alkyl group of from 7 to 17 carbon atoms and where n is a numeral from 6 to 18 are suitable for use as stabilizers in lubricant compositions. The sterically hindered amines are non-aggressive towards fluoroelastomer O-rings or seals.
Patent AU-2007299934-B2 (AU)
Title: Delivery tool for percutaneous delivery of a prosthesis
Inventor: JOHN GAINOR
IPC: A61F2/24
Filed: 2007-09-28
Granted: 2013-09-12
Abstract: An expandable delivery tool for aiding the deployment of a prosthesis device within a patient. The delivery tool has a generally elongated shape with a selectively expandable distal end region that flares outward in diameter. Once advanced percutaneously within a patient's vessel, the delivery device can help locate a target area, assist in deploying a prosthesis at a desired position and further expand the prosthesis after deployment.
Patent AU-2007306384-B2 (AU)
Title: Use of monoclonal antibodies specific to the O-acetylated form of GD2 ganglioside for the treatment of certain cancers
Inventor: SUPIOT STEPHANE
IPC: C12N15/13
Filed: 2007-10-10
Granted: 2012-04-12
Abstract: The invention relates to the use of monoclonal antibodies that only recognise the O-acetylated form of the GD2 ganglioside, or fragments of said antibody, for the diagnosis and the treatment of cancers in which the cells express the O-acetylated GD2, said antibody or said fragment recognising the O-acetylated GD2 molecules expressed by the tumoral cells and not recognising the GD2 molecules expressed at the surface of the peripheral nerves, in order to increase the specificity of the diagnosis and reduce the toxicity of the treatments. The invention also relates to artificially modified antibodies advantageously used for treating and diagnosing cancers in which the cells express the O-acetylated GD2.
Patent AU-2007322660-B2 (AU)
Title: Nucleic acid molecule capable of binding to rabbit-derived IgG antibody
Inventor: FURUICHI MAKIO
IPC: G01N33/53
Filed: 2007-11-22
Granted: 2013-09-26
Abstract: Disclosed is a nucleic acid molecule capable of binding to a rabbit anti-murine IgG antibody, which can be prepared in a simpler manner compared to an antibody and has a binding ability equivalent to or higher than that of an antibody. The nucleic acid molecule may have a sequence depicted in any one of SEQ ID NOs:1 to 5. The nucleic acid molecule may be a nucleic acid capable of binding to a rabbit-derived IgG antibody, or may substantially have a homology to a sequence for the nucleic acid. The nucleic acid molecule may have a coupling constant (K
Patent AU-2008200304-B2 (AU)
Title: Induction of the mitochondrial permeability transition
Inventor: HOGG PHILIP JOHN
IPC: G01N33/50
Filed: 2008-01-22
Granted: 2012-02-02
Abstract: INDUCTION OF THE MITOCHONDRIAL PERMEABILITY TRANSITION Abstract The present invention relates to process for identifying a compound which 5 induces the mitochondrial permeability transition (MPT) of proliferating cells, wherein said process comprises contacting a cell or cell extract with a compound, determining whether the compound binds to adenine nucleotide translocator (ANT), and determining whether the compound selectively induces the MPT in proliferating cells.
Patent AU-2008200997-B2 (AU)
Title: A conversion circuit
Inventor: LOH WALTER KEEN YONG
IPC: G05B15/00
Filed: 2008-03-03
Granted: 2012-08-02
Abstract: Abstract 5 The present invention relates to a circuit for converting data of a signal line in the form of logical pulses of current to RS 232 level voltages between an air-conditioner and a computer. The conversion circuit of the present invention is able to troubleshoot the communication signals between the indoor unit and outdoor unit of an air-conditioner.
Patent AU-2008202394-B2 (AU)
Title: Reusable diapers
Inventor: LABIT JENNIFER LYNN
IPC: A61F13/15
Filed: 2008-05-30
Granted: 2012-09-13
Abstract: REUSABLE DIAPERS A reusable diaper may include an inner layer to wick moisture and an outer layer substantially impervious to liquids. A waist portion may include a corner region for securing the diaper in a desired position. The corner region may be resiliently stretchable and substantially impervious to liquids, and may include first and second layers coupled to the respective inner and outer layers. The coupled first layer and inner layer define a first seam allowance, and the coupled second layer and outer layer define a second seam allowance. The first and second seam allowances may be positioned within the corner region to help inhibit wicking of liquid through the seam allowances into the corner region. And a fluid-resistant region may be provided to help resist wicking of moisture through the inner layer past the fluid-resistant region. \ ccc / cc
Patent AU-2008203020-B2 (AU)
Title: A footplate
Inventor: THOMAS ROGER
IPC: B23D47/02
Filed: 2008-07-08
Granted: 2013-11-21
Abstract: A footplate for a hand-held tool for guiding the tool along a guide, the footplate comprising on its lower surface at least one dual-restriction , wherein the first part of the or each dual-restriction is for engaging a rail extending in a longitudinal direction of a first guide on the upper surface of said first guide and the 5 second part of the or each dual-restriction is for engaging a rail extending in a longitudinal direction of a second different guide on the upper surface of said second guide, wherein the first and second parts of the or each dual-restriction each has a fixed side wall, characterised in that the first and second parts of the or each dual restriction have an adjustable side wall arranged opposite to a respective fixed side 10 wall. [Figure 7] (00 (N co, coN 0 00? (ND co, mi
Patent AU-2008229659-B2 (AU)
Title: A process for concentration of a polypeptide
Inventor: NILSSON STEFAN
IPC: A61K38/43
Filed: 2008-09-26
Granted: 2013-01-31
Abstract: The present invention comprises a method of concentrating a composition comprising a polypeptide of interest and the use of such a concentrated composition for the treatment of diseases in mammals, in particular by subcutaneous injection.
Patent AU-2008261163-B2 (AU)
Title: Module for the production of concrete elements and displacement body for this
Inventor: STUECKLIN MICHAEL
IPC: E04B1/04
Filed: 2008-12-22
Granted: 2012-01-19
Abstract: Module (1) for the production of concrete elements, particularly of concrete semi finished products or of relatively "thin" in-situ concrete surfaces, with a plurality of 5 displacement bodies (5, 5', 5", 5"') able to be inserted arranged adjacent to each other in a longitudinal direction, in which the plurality of displacement bodies (5, 5', 5", 5"') arranged adjacent to each other is arranged respectively undetachably in a latticework (2) of bars (3, 3', 4, 4', 4"), in which the displacement body (5, 5', 5", 5') is formed as a substantially oblate rotation ellipsoid with two at least slightly flattened pole sides 10 (7, 7', 8, 8'). (Fig. 1)
Patent AU-2008270966-B2 (AU)
Title: Removable adhesive tape and pull tab film, and kits
Inventor: BARTUSIAK JOSEPH T
IPC: C09J7/38
Filed: 2008-05-07
Granted: 2012-02-09
Abstract: Kits are described wherefrom a single tab film may be adhered to an elongated strip of stretch releasing adhesive tape to form a manually engageable pull tab at a selected location. Such a pull tab may be foldable so as to comprise an unobtrusive visual appearance, and may also be extendable so that the pull tab may be grasped to activate the stretch release.