baber/WOPTO huggingface dataset:
Patent AU-2010311559-A1 (AU)
Title: Dosage regimen for administering a CD19xCD3 bispecific antibody
Inventor: NAGORSEN DIRK
IPC: A61K39/395
Filed: 2010-10-27
Abstract: The present invention relates to a method for assessing (analyzing) the risk of potential adverse effects for a human patient mediated by the administration of a CD19xCD3 bispecific antibody to said patient comprising determining the ratio of B cells to T cells of said patient, wherein a ratio of about 1:5 or lower is indicative for a risk of potential adverse effects for said patient. Accordingly, the present invention relates a method (dosage regimen) for administering a CD19x CD3 bispecific antibody to a human patient having a B :T cell ratio of about 1:5 or lower, comprising (a) administering a first dose of said antibody for a first period of time; and consecutively (b) administering a second dose of said antibody for a second period of time, wherein said second dose exceeds said first dose.In some embodiments, a third dose of said antibody is administered for a third period of time. This dosage regimen can be applied in methods for treating malignant CD19 positive lymphocytes or for ameliorating and/or preventing an adverse effect mediated by the administration of said bispecific antibody. The present invention also relates to the use of a CD19x CD3 bispecific antibody for the preparation of a pharmaceutical composition to be used in a method of the present invention. A pharmaceutical package or kit comprising a first dose and a second dose and optionally a third dose of said antibody as defined in the methods/dosage regimen of the present invention is disclosed as well.
Patent AU-2010319028-A1 (AU)
Title: Corrosion resistant structure and corrosion protection method in high-temperature water system
Inventor: OKAMURA MASATO
IPC: C23F11/00
Filed: 2010-11-16
Abstract: Provided are a corrosion resistant structure and a corrosion protection method in a high-temperature water system that make it possible to run a plant without controlling cooling water quality by the injection of chemicals. The corrosion resistant structure in a high-temperature water system for passing high-temperature cooling water (4) is characterized in that a corrosion protection film (3) formed of a material containing at least one of La and Y is attached to a surface of a structural material (1) constituting the high-temperature water system, the surface being on the side contacting the cooling water (4).
Patent AU-2010323118-A1 (AU)
Title: Calibration method and angle measuring method for an angle measuring device, and angle measuring device
Inventor: LIPPUNER HEINZ
IPC: G01D5/244
Filed: 2010-11-25
Abstract: The invention relates to a calibration method that can be carried out without a reference system for an angle measuring device having a code carrier (2) carrying an absolute position code, and at least two reading heads (1a and 1b) comprising a fixed, known angle position (4) at an angular distance, in particular of more than (50) degrees, relative to each other, in particular wherein at least one of the angle distances between adjacent reading heads (1a,1b,1c,1d) differs from the other angle distances, and each detecting the position code at least partially, such that an absolute angle position value of each reading head can be determined relative to the code carrier, wherein the code carrier can be rotated (3) relative to the reading heads, and different angle positions of the code carrier relative to the reading heads can thus be captured, comprising the steps of: determining the angle position values of the reading heads (1a and 1b) in an angular setting; determining an angular error by comparing the difference of the angle position values of the reading heads to the known angular location (4) of the reading heads (1a and 1b) relative to each other; repeating the determining of the angle position values and the angular error for a plurality of varying angle settings, and performing a mathematical analysis method, comprising determining the parameters of a mathematical function quantifying the angular error, and determining calibration parameters as parameters of the quantifying mathematical function or as a correction or code table derived from the parameters.
Patent AU-2010332420-A1 (AU)
Title: Personal care composition providing quietness and softness enhancement and articles using the same
Inventor: CUNNINGHAM COREY THOMAS
IPC: A47K7/00
Filed: 2010-11-17
Abstract: The present disclosure generally relates to personal care compositions and personal care products. More particularly, the disclosure relates to personal care compositions and personal care products that impart perceivable aesthetic benefits of increased softness, quietness and drapability to the skin or hair of a user. To achieve the perceivable aesthetic benefit, a liquid composition containing water, a skin aesthetic agent selected from fatty acids, fatty alcohols, fatty acid derivatives, fatty alcohol derivatives, and/or combinations thereof, an acidifying agent, and an emulsifying agent may be incorporated into the personal care compositions and personal care products.
Patent AU-2010333173-A1 (AU)
Title: Antibiotic microparticles for inhalation
Inventor: MORTON DAVID
IPC: A61K31/7036
Filed: 2010-11-24
Abstract: The invention concerns a powder formulation for inhalation comprising microparticles consisting of an antibiotic and magnesium stearate. The invention also relates to a process for preparing said microparticles and to their use in the treatment of bacterial infections associated to certain pulmonary diseases.
Patent AU-2010334375-A1 (AU)
Title: Intaglio printing press with mobile carriage supporting ink-collecting cylinder
Inventor: SCHAEDE JOHANNES GEORG
IPC: B41F9/02
Filed: 2010-12-20
Abstract: There is described an intaglio printing press comprising (i) a stationary machine frame (01 ) supporting an intaglio printing cylinder (07) and an impression cylinder (06) contacting the intaglio printing cylinder (07), (ii) an inking system (12, 13, 16) for inking the intaglio printing cylinder (07), which inking system (12, 13, 16) comprises an ink-collecting cylinder (12) designed to contact the intaglio printing cylinder (07) and at least one inking device (13, 16) for supplying ink to said ink-collecting cylinder (12), and (iii) at least a first mobile carriage (1 1 ) supporting the ink-collecting cylinder (12), which first mobile carriage (1 1 ) is adapted to be moved with respect to the stationary machine frame (01 ) between a working position where the ink-collecting cylinder (12) contacts the intaglio printing cylinder (07) and a retracted position where the ink-collecting cylinder (12) is retracted away from the intaglio printing cylinder (07). The axis of rotation of the ink-collecting cylinder (12) lies below a horizontal plane (P0) intersecting the axis of rotation of the intaglio printing cylinder (07) and a plane (P2) intersecting the axis of rotation of the ink- collecting cylinder (12) and the axis of rotation of the intaglio printing cylinder (07) forms, in the working position of the first mobile carriage (11), an acute angle (β) with respect to the horizontal plane (P0).
Patent WO-2012000055-A1 (WO)
Title: Composition for prevention and treatment of contact lens papillary conjunctivitis and allergic eye disease
Inventor: HOLDEN BRIEN ANTHONY
IPC: A61K31/164
Filed: 2011-07-01
Abstract: The invention provides a use of panthenol or dexpanthenol in the prevention and/or treatment of contact lens papillary conjunctivitis in a subject. A contact lens care solution containing 0.001 to 10% by dry weight dexpanthenol is also provided.
Patent AU-2011202680-A1 (AU)
Title: Method and apparatus to facilitate message transmission and reception via wireline using different transmission characteristics
Inventor: LAIRD EDWARD T
IPC: H04L9/18
Filed: 2011-06-06
Abstract: METHOD AND APPARATUS TO FACILITATE MESSAGE TRANSMISSION AND RECEPTION VIA WIRELINE USING DIFFERENT TRANSMISSION CHARACTERISTICS Abstract of the Disclosure Upon providing (101) message content (such as a wireline remote control instruction) to be transmitted via wireline, and in conjunction with provision (102) of a plurality of different wireline transmission characteristics (as correspond, for example, to different types of wireline transmission) and a corresponding plurality of correlated recovery identifiers (103), a particular wireline transmission characteristic is selected (104) and used to transmit via wireline (105) a joint message. In particular, in a preferred approach, the selected wireline transmission characteristic (106) is used when transmitting via wireline at least a portion of the message content portion of the joint message while another part of the joint message carries the recovery identifier to thereby facilitate selection of an appropriate reception technique by a wireline receiver when receiving the joint message. PROVIDE MESSAGE CONTENT TO BE TRANSMITTED PROVIDE DIFFERENT TRANSMISSION CHARACTERISTICS PROVIDE CORRELATED RECOVERY SELECT A PARTICULAR TRANSMISSION CHARACTERISTIC 10%1051 SELECTED TRANSMIT A JOINT MESSAGE TRANSMISSION - CORRESPONDING TRANSMISSION CHARACTERISTIC H CHARACTERISTIC - MESSAGE CONTENT 200 201-,. 202--, RECOVERY IDENTIFIER I MESSAGE CO NTENT RECOVERY IDENTIFIER MESSAGE CONTENT
Patent AU-2011202960-A1 (AU)
Title: Ascender/descender appliance for climbing and descending on a rope
Inventor: MAURICE ALAIN
IPC: A63B29/02
Filed: 2011-06-21
Abstract: Abstract An ascender/descender appliance for ascending and descending on a rope comprising a body 11 having attachment means designed to be connected to 5 the user's harness and a clamping device able to be released on load. The clamping device is arranged outside the body 11 and comprises a chain of metal links 18 constituted by a succession of friction elements 19 articulated on one another by connecting rods 21 to form a series of gaps 22 for the rope 23 to pass in zigzag manner. Means are associated with the top link 24 10 to trigger clamping of the ascender device. (Figure 1) FIG 1 FIG 2
Patent AU-2011203012-A1 (AU)
Title: Tuberculosis vaccines comprising antigens expressed during the latent infection phase
Inventor: CLAUS AAGAARD
IPC: A61P31/06
Filed: 2011-06-21
Abstract: The invention is related to an immunogenic composition, vaccine or pharmaceutical 5 composition for preventing, boosting or treating infection caused by a species of the tuberculosis complex (M. tuberculosis, M bovis, M. africanum, M. microti). The immunogenic composition, vaccine or pharmaceutical composition comprise a fusion polypeptide, which comprises one or more starvation antigens from M.tuberculosis, the units of the fusion polypeptide being M. tuberculosis antigens. Further, the invention is related to 0 the use of a vaccine comprising a fusion polypeptide sequence or nucleic acid sequence of the invention given at the same time as BCG, either mixed with BCG or administered separately at different sites or routes for preparing said immunogenic composition, vaccine, or pharmaceutical composition.
Patent AU-2011207101-A1 (AU)
Title: Estimation of signal to noise ratio in receivers
Inventor: LI YUNXIN
IPC: H04B1/10
Filed: 2011-01-18
Abstract: This invention concerns the estimation of signal to noise ratio (SNR) at a communications receiver; it may be applicable to a wide range of receivers but is particularly suited for Orthogonal Frequency Division Multiplexing (OFDM) receivers. In particular the invention is a method, a receiver and software for performing the method. The signal to noise ratio (SNR) in the received signals is estimated by directly estimating the power ratio, in the received signal, between the part of the frequency spectrum of the received signal that contains only noise, and the part of the spectrum that contains both signal and noise; and averaging this value over a time interval.
Patent AU-2011229069-A1 (AU)
Title: Multifunctional air-conditioning and hot-water system
Inventor: GUO LIHUA
IPC: F25B30/02
Filed: 2011-01-25
Abstract: Disclosed is a multifunctional air-conditioning and hot-water system which comprises a special three-way valve (2), a four-way valve (3), an outdoor heat exchanger (5), an indoor heat exchanger (6), a multifunctional throttling channel conversion device (7) and a pressure relief device (8). An inlet of the special three-way valve (2) is connected with an air outlet of a compressor (1), one outlet of the special three-way valve (2) is connected with an inlet of a heat-exchange pipeline (41) of a water-heating exchanger (4), the other outlet of the special three-way valve (2) is connected with an inlet of the four-way valve (3), and an additional channel is connected with an inlet of the pressure relief device (8). A water outlet controller (110) linked with the special three-way valve (2) is arranged at the hot water outlet end of the water-heating exchanger (4). Three outlets of the four-way valve (3) are respectively connected with a heat exchange pipeline (51) of the outdoor heat exchanger (5), a heat exchange pipeline (61) of the indoor heat exchanger (6) and an air return port of the compressor (1). The outlet of the heat exchange pipeline (41) of the water-heating exchanger (4), the other end of the heat exchange pipeline (51) of the outdoor heat exchanger (5) and the other end of the heat exchange pipeline (61) of the indoor heat exchanger (6) are respectively connected with three ports of the multifunctional throttling channel conversion device (7).
Patent AU-2011236062-A1 (AU)
Title: Temperature Prediction System and Method
Inventor: BUTTERFIELD ROBERT D
IPC: G01K7/42
Filed: 2011-10-17
Abstract: Abstract A thermometer system and method that rapidly predict body temperature based on the temperature signals received from a temperature sensing probe when it comes into contact with the body. A nonlinear, multi-parameter curve fitting process is performed and depending on the errors in the curve fit, parameters are changed or a prediction of the temperature is made. Criteria exist for the differences between the curve fit and the temperature data. The processor switches to a Continuous Monitor State if the curve fit over a limited number of time frames is unacceptable. Determining the start time on which the measurement time frame for prediction is based is performed by tissue contact threshold coupled with a prediction time delay.
Patent AU-2011241875-A1 (AU)
Title: Automatic stage design of hydraulic fracture treatments using fracture height and in-situ stress
Inventor: GU HONGREN
IPC: E21B49/00
Filed: 2011-04-12
Abstract: A method for treating a subterranean formation comprising measuring mechanical properties of a formation comprising Young's modulus, Poisson's ratio, and in-situ stress; determining formation fracture height based on the mechanical properties; estimating number and location of hydraulic fractures based on the determining; identifying hydraulic fracturing treatment stages based on the estimating; and performing hydraulic fracturing treatments in the stages. A method for treating a subterranean formation comprising measuring mechanical properties of a formation comprising Young's modulus, Poisson's ratio, and in-situ stress; determining a target zone based on the mechanical properties; estimating number and location of hydraulic fractures based on the determining; identifying hydraulic fracturing treatment stages based on the estimating; and performing hydraulic fracturing treatments in the stages.
Patent AU-2011246960-A1 (AU)
Title: Remotely powered and remotely adjustable gastric band system
Inventor: FRIDEZ PIERRE
IPC: H02J7/00
Filed: 2011-04-28
Abstract: A remotely adjustable remotely power gastric band system may include a control device, an implant electronic device, and an implantable gastric band. The control device may telemetrically power and communicate with the implant electronic device, which may be used for adjusting the diameter of the implantable gastric band. The implant electronic device may store the gastric band adjustment history records of a patient and regulate the power received from the control device. To improve transmission efficiency, the implant electronic device may adopt a double modulation scheme for communicating with the control device. Furthermore, the implant electronic device may detect and resolve motor blockage issues related to the implantable gastric band.
Patent AU-2011263785-A1 (AU)
Title: Method for cultivating sugar cane
Inventor: DEGASPARI NILTON
IPC: A01N37/46
Filed: 2011-06-08
Abstract: The present invention relates to a method for cultivating sugar cane comprising planting sugar cane shoots in a growth medium, growing seedlings from the shoots at a temperature of at least 15°C and 10-120 days after having planted the shoots planting the seedlings obtained therefrom into the field if the growth medium is not a field, or, in case the growth medium is a field, exposing the seedlings obtained from the shoots to ambient conditions, where the seedling, while growing, is treated with at least one strobilurin fungicide and/or at least one carboxamide fungicide and/or at least one GABA antagonist insecticide and/or at least one nicotinic receptor agonists/antagonist insecticide and/or at least one chloride channel activator insecticide.
Patent AU-2011265509-A1 (AU)
Title: RNA constructs
Inventor: VAN DE CRAEN MARC
IPC: C12N5/10
Filed: 2011-12-22
Abstract: C:\NRPonbDCC\KXG\46594 11. DOC-21112/2011 The present invention concerns concatemer and/or stabilized RNA constructs capable of forming dsRNA, optionally comprising a sequence capable of protecting the dsRNA against RNA processing in a host cell. The invention also relates to methods of producing these constructs and to methods for using these constructs. The constructs according to the present 5 invention are particularly useful in plant pest control.
Patent AU-2011288256-A1 (AU)
Title: Oral controlled release pharmaceutical compositions of Blonanserin
Inventor: BHUTADA PRAVIN MEGHRAJJI
IPC: A61K9/20
Filed: 2011-08-10
Abstract: An oral controlled release pharmaceutical composition comprising Blonanserin and release controlling agent(s) and optionally pharmaceutically acceptable excipients is provided. The present invention further relates to a controlled release pharmaceutical composition comprising Blonanserin and release controlling agent(s) such that the composition releases not less than about 80% of Blonanserin within 20 hours, when dissolution is carried out in 900 ml, 0.1 N HCI, USP apparatus Type II (Paddle) at 50 rpm for 20 hrs. The controlled release pharmaceutical composition of the invention releases 50% of Blonanserin between about 4 to 14 hours, when dissolution is carried out in 900 ml, 0.1 N HCI, USP apparatus Type II (Paddle) at 50 rpm.
Patent AU-2011291068-A1 (AU)
Title: System for storing potential energy and method for producing such a system
Inventor: HEINDL EDUARD
IPC: F03G3/00
Filed: 2011-08-05
Abstract: The invention relates to a system for storing potential energy (10), comprising a hydraulic cylinder (2), a mass (1) to be lifted, and a sealing ring (33) at the edge of the mass (1) to be lifted, wherein the mass (1) to be lifted is a solid rock mass in the form of a cut-out solid rock, wherein the hydraulic cylinder (2) is formed by the cavity between surrounding rocks and the cut-out solid rock, and wherein the cavity is sealed with respect to the surrounding rocks by the sealing ring (33). The invention further relates to a method for producing such a system.
Patent AU-2011292206-A1 (AU)
Title: Method and system for eliminating fuel consumption during dynamic braking of electric drive machines
Inventor: MARCHAND DAVID G
IPC: B60W10/18
Filed: 2011-08-16
Abstract: A drive system (100, 100a-c) for an electric drive machine (102, 102a-c) having an engine (104, 104a-c), a generator (106, 106a-c), a motor (108, 108a-c), final drive wheels (110, 110a-c) and auxiliary devices (116, 116a-c) is provided. The drive system (100, 100a-c) may include an inverter circuit (118, 118a-c) and an auxiliary driver (120, 120a-c). The inverter circuit (118, 118a-c) may be coupled to each of the generator (106, 106a-c) and the motor (108, 108a-c). The auxiliary driver (120, 120a-c) may be coupled to each of the generator (106, 106a-c) and the auxiliary devices (116, 116a-c). The inverter circuit (118, 118a-c) and the auxiliary driver (120, 120a-c) may be configured to automatically communicate power from the engine (104, 104a-c) and any power from the auxiliary devices (116, 116a-c) to the motor (108, 108a-c) in a propel mode, and automatically communicate power from the motor (108, 108a-c) to the engine (104, 104a-c), and optionally to a hybrid system (132) if applicable, in a dynamic braking mode so as to minimize fuel consumption during the dynamic braking mode.
Patent AU-2011322553-A1 (AU)
Title: Liposome-based construct comprising a peptide modified through hydrophobic moieties
Inventor: REIS PEDRO
IPC: A61K39/00
Filed: 2011-10-26
Abstract: The present invention relates to method for preparing liposome-based constructs comprising a peptide, particularly an antigenic peptide, of interest modified through hydrophobic moieties reconstituted in liposomes and to the antigenic constructs obtained with said method. The invention further relates to the use of said constructs for the therapeutic and diagnostic use in the treatment of diseases and disorders, which are caused by or associated with proteopathy such as Alzheimer's Disease.
Patent AU-2011373387-A1 (AU)
Title: Neutralizing anti-influenza A virus antibodies and uses thereof
Inventor: LANZAVECCHIA ANTONIO
IPC: C07K14/11
Filed: 2011-07-18
Abstract: Antibodies, and antigen binding fragments thereof, that specifically bind to an epitope in the stem region of an influenza A hemagglutinin trimer and neutralize a group 1 subtype and a group 2 subtype of influenza A virus. Nucleic acids that encode, immortalized B cells and cultured single plasma cells that produce, and to epitopes that bind to such antibodies and antibody fragments. In addition, the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, treatment and prevention of influenza A virus infection.
Patent AU-2012202107-A1 (AU)
Title: Gaming apparatus with special symbols
Inventor: BENNETT NICHOLAS
IPC: A63F13/00
Filed: 2012-04-12
Abstract: Abstract A method of determining a plurality of outcomes of a game of chance played on a computational gaming apparatus. The method will typically be employed in a spinning reel type game although the method may be employed with other games or on other 5 gaming machines. In a spinning reel game the method may be implemented by providing a first game event in which a plurality of symbols are spun up on a plurality of spinning reels to form an array of symbols, each spinning reel spinning up at least three symbols and at least one of the spinning reels being defined so that at least two feature symbols can be simultaneously spun up on that reel. The result of the spin is then 0 evaluated to assess whether two or more feature symbols have been spun up on the same reel and, if so, a second game event is provided in which the two or more feature symbols and all other the symbols spun up on the same reel are converted to special symbols. The special symbols have an enhanced play characteristic in comparison to the other symbols, and the outcome of the game is then re-evaluated to establish 15 whether any outcomes exist which define a winning combination. A prize or an award is awarded if one or more winning combinations exist. The invention extends to a gaming machine on which the method is played.