baber/WOPTO huggingface dataset:
Patent AU-626598-B2 (AU)
Title: Body support system
Inventor: HIGGINS LARRY
IPC: G05D16/06
Filed: 1989-10-11
Granted: 1992-08-06
Abstract: An air bed (10) comprising an air mattress (25) having a plurality of interconnected rows and columns of air cells (35) divided into longitudinally isolated zones (41-45), and an airflow control system (15) for supplying air at differing pressures to the zones such that a person reclining atop the mattress is supported and maintained in spinal alignment at subischemic applied pressures.
Patent AU-576886-B2 (AU)
Title: 1-aminophenyl-2-aminopropanone derivatives
Inventor: LAFON LOUIS
IPC: A61K31/00
Filed: 1985-08-20
Granted: 1988-09-08
Abstract: 1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A 1-(aminophenyl)-2-aminopropanone derivative selected from the group consisting of : a) compounds of the general formula (I)   see diagramm : EP0174242,P25,F1   in which X is NH2 , Y is H or a halogen atom, Z is H or a halogen atom, R1 is C1 -C4 alkyl or C3 -C6 cycloalkyl and R2 is H or C1 -C4 alkyl or R1 and R2 , taken together, can form, with the nitrogen atom to which they are bonded, an N-heterocyclic group having from 5 to 7 ring members and which can be substituted, said NR1 R2 groups being selected from the group comprising the pyrrolidino, morpholino, thiomorpholino, piperidino, hexamethyleneimino, piperazino, 4-methylpiperazino and 4-(beta-hydroxyethyl)piperazino, 4-phenylpiperazino and 4-(p-chlorophenyl) piperazino groups ; and b) addition salts thereof. 1. Claims for the Contracting State : AT A method for the preparation of a 1-(aminophenyl)-2-aminopropanone derivative of the general formula : (I)   see diagramm : EP0174242,P26,F1   in which X is NH2 , is H or a halogen atom, Z is H or a halogen atom, R1 is C1 -C4 alkyl or C3 -C6 cycloalkyl and R2 is H or C1 -C4 alkyl, or R1 and R2 , taken together, can form, with the nitrogen atom to which they are bonded, an N-heterocyclic group having from 5 to 7 ring members and which can be substituted, said NR1 R2 groups being selected from the group consisting of the pyrrolidino, morpholino, thiomorpholino, piperidino, hexamethyleneimino, piperazino, 4-methylpiperazino and 4-(beta-hydroxyethyl)-piperazino, 4-phenylpiperazino and 4-(p-chlorophenyl) piperazino groups, and addition salts thereof, the said method comprising subjecting a 1-(acetylaminophenyl)-2-amino-propanone derivative of the formula : (II)   see diagramm : EP0174242,P26,F2   in which Y, Z, R1 and R2 are defined as indicated above, to a deacetylation reaction with an aqueous solution of HCI, for at least 0,25 hour, at the reflux temperature of the reaction medium, whereby 1 mol of compound II is used for 0,7 to 2 liters of 4 n HCI.
Patent AU-667743-B2 (AU)
Title: Monoclonal antibody recognizing FK506-binding protein, method of assaying FK506-binding protein level, and kit thereof
Inventor: KOBAYASHI MASAKAZU
IPC: C12P21/08
Filed: 1993-08-11
Granted: 1996-04-04
Abstract: The invention relates to a monoclonal antibody (anti-FKBP antibody) which recognizes an antigenic determinant present in an FK506-binding protein (FKBP) and does not inhibit the binding between FKBP and FK506, a method of assaying a plasma FKBP level which comprises reacting an immobilized anti-FKBP antibody with an enzyme-labelled FK506 and FKBP present in a specimen and determining the extent of color development of the enzyme-substrate complex formed thereby, and a kit therefor. The invention serves to facilitate a more accurate assay of a plasma FKBP level which affects the immunosuppressive activity of FK506, whereby the optimal FK506 dose can be determined in close accordance with the condition of each individual patient.
Patent AU-591464-B2 (AU)
Title: Method of removing n-terminal amino acid residues using aeromonas aminopeptidases
Inventor: BLUMBERG SHMARYAHU
IPC: C12N15/20
Filed: 1985-08-09
Granted: 1989-12-07
Abstract: The invention relates to a method of producing a human growth hormone having the amino acid sequence of naturally occurring human growth hormone which comprises   a) producing in a microbial host a first polypeptide which is characterized by the presence of one or more additional amino acids at the N-terminus of the amino acid sequence of naturally occurring human growth hormone; b) contacting the first polypeptide so produced with an enzyme, preferably an aminopeptidase, so as to produce a second polypeptide having the amino acid sequence of naturally occurring human growth hormone; and   c) recovering the second polypeptide so produced.   A preferred microbial host is a bacterium, especially E. coli.
Patent AU-765860-B2 (AU)
Title: Antiparasitic artemisinin derivatives (endoperoxides)
Inventor: HAYNES RICHARD KINGSTON
IPC: A61K31/357
Filed: 1999-07-14
Granted: 2003-10-02
Abstract: This invention relates to the use of certain C-10 substituted derivatives of artemisinin in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substituted derivatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis.
Patent AU-596791-B2 (AU)
Title: New carbonic acid esters
Inventor: PETER HEINRICH
IPC: A61K31/265
Filed: 1985-12-13
Granted: 1990-05-17
Abstract: PCT No. PCT/CH85/00175 Sec. 371 Date Aug. 11, 1986 Sec. 102(e) Date Aug. 11, 1986 PCT Filed Dec. 13, 1985 PCT Pub. No. WO86/03747 PCT Pub. Date Jul. 3, 1986.N- and/or O-acylates, derived from carbonic acid monoesters, of desferrioxamine B of the formula   <IMAGE> (I) <IMAGE>  the symbols having the following meanings: each of AA1, AA2 and AA3, independently of the others, is hydrogen, an acyl radical, referred to as Ac, of a carboxylic acid having from 1 to 24 carbon atoms, or an esterified oxycarbonyl radical referred to as Cb (acyl radical of a carbonic acid monoester) having a total of from 2 to 25 carbon atoms, and B has one of the meanings of Cb or, if at least one of the symbols AA1, AA2 and AA3 represents Cb, it may also be hydrogen or an amino-protecting group referred to as X, form strong iron (III) and aluminum complexes within living cells and can therefore be used therapeutically for the treatment of warm-blooded animals, including humans, for pathological conditions associated with an excess of iron (III) or aluminum in the body or caused by iron (III)-dependent pathogenic organisms; they can also be used as intermediates for the manufacture of therapeutically effective derivatives of desferrioxamine B. The compounds according to the invention can be obtained by conventional acylation of the free amino group and/or hydroxy groups in desferrioxamine B or a suitable derivative thereof using a chloroformic ester or a similar reactive carbonic acid derivative.
Patent AU-673213-B2 (AU)
Title: Quinoline or quinazoline derivatives, their production and use
Inventor: SOHDA TAKASHI
IPC: A61P29/00
Filed: 1994-01-27
Granted: 1996-10-31
Abstract: A compound represented by the general formula: <CHEM> wherein Y represents a nitrogen atom or C-G (G represents a carboxyl group which may be esterified); ring R is a nitrogen-containing unsaturated heterocyclic group which may be substituted for; each of rings A and B may have a substituent; n represents an integer from 1 to 4; k represents the integer 0 or 1, or a salt thereof, which serves well as an anti-inflammatory agent, particularly a therapeutic agent for arthritis.
Patent AU-611610-B2 (AU)
Title: Pyridazinone derivatives
Inventor: MYLARI BANAVARA LAKSHMANA
IPC: A61P13/02
Filed: 1990-05-10
Granted: 1991-06-13
Abstract: A series of novel 6-substituted-5-oxo-6H-pyrido[2,3-d]pyridazine-8-ylacetic acid and 7-substituted-8-oxo-7H-pyrido[2,3-d]pyridazine-5-ylacetic acid compounds have been prepared, including their C1-C6 alkyl ester derivatives, as well as the base salts of said acids with pharmacologically acceptable cations. Typical member compounds include those acids wherein the ring substituent is always attached to the available ring-nitrogen atom and is either a lower aralkyl group or a lower heteroaralkyl group. These compounds are useful in therapy as aldose reductase inhibitors for the control of certain chronic diabetic complications. Methods for preparing these compounds from known starting materials are provided.
Patent AU-685410-B2 (AU)
Title: Waveguide lens and method for manufacturing the same
Inventor: PETERSSON STIG ANDERS
IPC: H01Q15/04
Filed: 1993-11-10
Granted: 1998-01-22
Abstract: In a waveguide lens for primarily circularly or linearly polarized electromagnetic radiation there is one or several rotationally symmetrical rings, arranged concentrically about a lens axis, for focusing of the incoming part of an electric magnetic wave, which has a polarization parallel to the rings, to a focus. For a still more efficient reception one or more plates arranged radially are designed so that the radial component of the electromagnetic wave is focused to the same focus. Alternatively there is instead of rings one or more spiral arms extending from the lens axis. The lens eliminates the problem of existing lens types that they only receive waves having a predetermined polarization which must be adapted to the orientation of the lens plates and the phase shifting elements. It makes for instance the reception of satellite signals more difficult, where the satellite signal is polarized in relation to the earth axis and the latitude where the satellite is located. The lens focuses all polarizations equally much which is especially favourable for circularly polarized waves but is also valid for plane polarized waves.
Patent AU-588597-B2 (AU)
Title: X-ray film cassette for daylight system
Inventor: SINGER RUDOLF
IPC: G03B42/04
Filed: 1986-06-03
Granted: 1989-09-21
Abstract: The disclosure involves an x-ray daylight cassette with shortened unloading times. The cassette, which has a film insertion slot on one side, contains two intensifying screens, one of which is affixed to the pressure plate so that the screen has edge zones that are not bonded to the pressure plate on the two long dimensions and optionally, on the short dimension opposite the film insertion slot.
Patent AU-701177-B2 (AU)
Title: Standoff
Inventor: WHITE FREDERICK E JR
IPC: H02G3/30
Filed: 1996-07-03
Granted: 1999-01-21
Abstract: A standoff for use with a cable tie for securing a wire bundle at a spaced distance from a mounting panel including a pair of opposing strap passageways extending from a top to a bottom side of the standoff and including access slots connecting the strap passageways to the exterior of the body. <IMAGE>
Patent AU-621235-B2 (AU)
Title: Flexible bowl tip truck
Inventor: OSTERMEYER BERND
IPC: B61D/
Filed: 1990-06-27
Granted: 1992-03-05
Abstract: PCT No. PCT/AU90/00274 Sec. 371 Date May 28, 1991 Sec. 102(e) Date May 28, 1991 PCT Filed Jun. 27, 1990 PCT Pub. No. WO91/00195 PCT Pub. Date Jan. 10, 1991.A tipping system for use in a vehicle including a container having an upper perimetrical frame with an open top and a bowl made of flexible material is suspended from the frame and including means to interact with the bowl in the discharge position to control the shape of the bowl so that contents carried therein will gravity discharge over one side of the perimetrical frame, is disclosed.
Patent AU-641183-B2 (AU)
Title: Pyrrolo(2,3-d)pyrimidine derivative, process for preparing the same, and pharmaceutical preparation comprising the derivative as active ingredient
Inventor: SAKUMA YASUJI
IPC: C07D519/00
Filed: 1990-09-19
Granted: 1993-09-16
Abstract: A pyrrolo[2,3-d]pyrimidine derivative represented by general formula (1), wherein R<1> represents H or a hydrocarbon residue; R<2> and R<3> each independently represent H a hydrocarbon residue or an acyl group, provided that R<2> and R<3> may combine with a neighboring N atom to form a cyclic amino group; R<4> and R<5> each independently represent H, a halogen atom or an alkyl group; Y represents a linear or cyclic amino group bonding through an N atom with the pyrimidine ring: Z represents H, a hydrocarbon residue, an acyl group, a carboxyl group, a hydroxyl group, an alkoxycarbonyl group, an acyloxy group, an alkoxy group, an alkoxyiminoalkyl group or an amino group, provided that Z may form in cooperation with Z a morpholino group or a thiomorpholino group. <CHEM>
Patent AU-704955-B2 (AU)
Title: Use of CGMP-phosphodiesterase inhibitors to treat impotence
Inventor: DAUGAN ALAIN CLAUDE-MARIE
IPC: A61P13/02
Filed: 1996-07-11
Granted: 1999-05-13
Abstract: The use of (6R, 12aR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)-pyrazino[2',1':6,1]pyrido[3,4-b]indole -1,4-dione, (3S, 6R, 12aR)-2,3,6,7,12,12a-hexahydro-2,3-dimethyl-6-(3,4-methylenedioxyphenyl)pyrazino[2', 1':6,1]pyrido[3,4-b]indole-1,4-dione, and physiologically acceptable salts and solvates thereof, in the treatment of impotence.
Patent AU-638758-B2 (AU)
Title: Tetracyclic imidazoquinazoline derivatives, preparation and pharmaceutical compositions
IPC: A61P25/20
Filed: 1990-09-06
Granted: 1993-07-08
Abstract: New imidazoquinazoline compounds having the general formula <CHEM> wherein A together with the alpha -marked carbon atom and the  beta -marked nitrogen atom is one of the groups <CHEM> wherein R<4>, R<5>, R<6> and R<7> independently are hydrogen, halogen C1-6-alkyl, aryl or aralkyl R<1> is <CHEM>  cyano or CO2R<8>, wherein R<8> is hydrogen, C1-6-alkyl or C3-7-cycloalkyl, trifluoromethyl or C1-6-alkoxymethyl, R<2> and R<3> independently are hydrogen, halogen, CN, C1-6-alkyl, C2-6-alkenyl, C2-6-alkynyl, trifluoromethyl, C1-6-alkoxy, dialkylaminoalkoxy, aralkoxy, aryloxy which may be substituted with halogen or alkoxy, a cyclic amino group, or NR<9>R<1><0> wherein R<9> and R<1><0> independently are hydrogen or C1-6-alkyl. The compounds are useful in psychopharmaceutical preparations as anticonvulsants, anxiolytics, hypnotics, antipsychotics, antiemetics, or in improving the cognitive function of the brain of mammals.
Patent AU-716716-B2 (AU)
Title: Cysteine protease inhibitors for use in treatment of IgE mediated allergic diseases
Inventor: JOHNSON TONY
IPC: C07K5/083
Filed: 1996-07-17
Granted: 2000-03-02
Abstract: PCT No. PCT/GB96/01707 Sec. 371 Date Feb. 26, 1998 Sec. 102(e) Date Feb. 26, 1998 PCT Filed Jul. 17, 1996 PCT Pub. No. WO97/04004 PCT Pub. Date Feb. 6, 1997The invention provides compounds for use in the treatment of allergic diseases including juvenile asthma and eczema. The compounds can inhibit IgE mediated reaction to major environmental and occupational allergens and can also have a prophylactic effect against allergic disease by preventing allergic sensitization to environmental and occupational allergens when administered to at-risk individuals (e.g., those at genetic risk of asthma and those exposed to occupational allergens in the workplace). The compounds are also useful for inactivation or attenuation of the allergenicity of allergens in situ. The invention provides compounds and ligands per se, pharmaceutical compositions containing the compounds, processes for producing the compounds and pharmaceutical compositions, and methods for using the compounds and compositions in treatment or prophylaxis of IgE mediated allergic diseases and in inactivation or attenuation of allergens in situ. The invention also enables the reduction or destruction of the viability of allergy-causing organisms.
Patent AU-700121-B2 (AU)
Title: Bending mold for bending glass sheets
Inventor: LAMMI PETRI
IPC: C03B23/025
Filed: 1996-08-14
Granted: 1998-12-24
Abstract: PCT No. PCT/FI96/00439 Sec. 371 Date Apr. 17, 1998 Sec. 102(e) Date Apr. 17, 1998 PCT Filed Aug. 14, 1996 PCT Pub. No. WO97/08109 PCT Pub. Date Mar. 6, 1997A bending mold for bending glass sheets is provided. The mold comprises a frame having longitudinally parallel side walls and a bottom. Support devices having support surfaces are connected between the side walls. An elongated member is provided on the bottom of the frame and is movable in relation to the frame. Support arms are connected by joints between the support device and the elongated member. Movement of the elongated member twists the support devices about a horizontal twisting center.
Patent AU-624755-B2 (AU)
Title: Control of corrosion in aqueous systems using certain phosphonomethyl amine oxides
Inventor: HWA CHIH MING
IPC: C02F5/12
Filed: 1990-11-29
Granted: 1992-06-18
Abstract: This invention relates to controlling corrosion in aqueous systems and more particularly to using certain calcium insensitive phosphonomethyl amine oxide compounds. The compounds of this invention are water soluble phosphonomethyl amine oxides having at least one oxidized tertiary amine group of the formula: <CHEM> and water soluble salts thereof and having a cloud point of at least about 25 ppm.
Patent AU-632879-B2 (AU)
Title: Safety gear
IPC: B66B5/22
Filed: 1990-12-12
Granted: 1993-01-14
Abstract: A safety gear designed to be mounted on an elevator car (1) moving along guide rails (7), comprising a frame (4), an area of wedge housings (3d,6d) formed in the frame, and wedges (3,6) placed in the wedge housings on each side of the guide rail (7), said wedges gripping the guide rail when the safety gear is activated, the wedges being so placed relative to each other that the wider end of one wedge (3) points upwards while the wider end of the other wedge (6) points downwards. To allow safety gear action in both upward and downward directions, the safety gear is provided with an activating means (10) connected to and moving both wedges, and an overspeed governor or equivalent for controlling the activating means.
Patent AU-678483-B2 (AU)
Title: Antibody fragments in therapy
Inventor: LANDON JOHN
IPC: A61P31/04
Filed: 1994-06-03
Granted: 1997-05-29
Abstract: A method of clotting blood comprising placing blood into a container and moving said container so that the blood platelets are damaged by contacting an inner surface of the container. <IMAGE>
Patent AU-692163-B2 (AU)
Title: Retroviral vector for the transfer and expression of genes for therapeutical purposes in eucaryotic cells
Inventor: COHEN-HAGUENAUER ODILE
IPC: A61K31/70
Filed: 1994-06-30
Granted: 1998-06-04
Abstract: The invention relates to a recombinant vector for the cloning and/or expression and/or transfer of an exogenous nucleotide sequence characterized in that it consists of any sequence contained in the ClaI-PvuII fragment comprising nucleotides 7702 to 1527 (SEQ ID NO: 11) of the sequence given in FIGS. 1A-1D and comprising the LTR sequence included between nucleotides 7842 and 144, the PBS site starting at nucleotides 145, the packaging sequence included in the sequences of 250 nucleotides following the end of the LTR sequence, the said sequence being capable of controlling the cloning and/or expression and/or transfer at the exogenous sequence whatever its transcriptional orientation with respect to the transcriptional orientation of the virus. It relates to the use of this vector for the transfer and/or cloning and/or expression of genes, in particular in the context of gene therapy.
Patent AU-723605-B2 (AU)
Title: Apparatus and process for multiple chemical reactions
Inventor: MOHAN RAJU
IPC: B01J19/00
Filed: 1996-09-23
Granted: 2000-08-31
Abstract: Multiple chemical reactions are performed in a plurality of reaction vessels (12) mounted in inlets in a manifold valve block (30). The manifold valve block (30) is connected to a channel block (34) which is utilized in conjunction with a solvent delivery system (21) as part of the reaction cycle. The solvent fluid is drained from the reaction vessels (12) when valves in the manifold valve block (30) are opened while applying a vacuum thereto. Optionally, a thermal block (40) may be utilized in conjunction with the manifold valve block (30) and the channel block (34) to facilitate the reaction. Upon completion of the reactant cycle, the manifold valve block (30) is disconnected from the channel block (34) and connected to a cleavage block assembly (120, 121) which contains vials (128) for collecting reaction products. The cleavage product is drained from the reaction vessels (12) through the manifold valve block (30) into the vials (128) upon opening the valves in the manifold valve block (30) and applying a vacuum to the channel block (34).
Patent AU-641003-B2 (AU)
Title: Arrangement for transferring castable material without pipes from a feeding means to a destination
Inventor: SPIES PROFESSOR DR-ING KLAUS
IPC: B65G31/02
Filed: 1991-04-22
Granted: 1993-09-09
Abstract: An arrangement for transferring castable material without pipes or conduits from a feeding point to a destination, particularly in underground mining. The arrangement includes a driven centrifugal wheel with blades. The centrifugal wheel is radially open and is surrounded in the manner of a jacket by an endless housing belt which is guided on guide rollers. The portion of the centrifugal wheel which is radially open is bordered by the guide roller which causes the housing belt to contact the centrifugal wheel and by the guide roller which raises the housing belt from the centrifugal wheel. The material is radially discharged in a concentrated manner through this radially open portion. The material is supplied axially to the centrifugal wheel through a feed tube and enters through a discharge opening of the feed tube on the vertical level of the blades into the centrifugal wheel.
Patent AU-646313-B2 (AU)
Title: Chemical Process
Inventor: JONES JOHN DAVID
IPC: C07D307/83
Filed: 1991-11-12
Granted: 1994-02-17
Abstract: Processes for the preparation of compounds (X), (XI) and (XII): <CHEM>   <CHEM>   <CHEM> where M is an alkali metal or alkaline earth metal and n is 1 or 2, and for obtaining compound (X) in a substantially pure form. These compounds are useful intermediates in the manufacture of fungicides.
Patent AU-717663-B2 (AU)
Title: Biocompatible immunoisolatory capsules containing genetically altered cells
Inventor: BAETGE E EDWARD
IPC: A61K38/02
Filed: 1998-12-17
Granted: 2000-03-30
Abstract: An encapsulated cell system for implantation in the human CNS comprises one or more biocompatible capsules, each capsule containing one or more cells, said cells producing a growth or trophic factor, the encapsulated cell system producing 1-1500 ng/day of the growth or trophic factor, particularly NGF. <IMAGE>
Patent BG-61121-B2 (BG)
Title: Compounds, derivatives of indane, method of their obtaining and intermediate products of their obtaining, their application as medicinal products and pharmaceutical compositions, containing them
Inventor: CLEMENCE FRANCOIS
IPC: C07D295/135
Filed: 1994-02-23
Abstract: The application relates to the products: <IMAGE> where R1 and R2 represent H or alkyl or together form a cycloalkyl, optionally including a heteroatom and  either R6 and R7 represent halogen, alkyl or alkoxy,  A or B represents <IMAGE> and the other A or B represents <IMAGE> or R6 and R7 represent H, B represents pyrrolidine and A represents N-methyl- 3-nitrobenzeneacetamide or 3,5-bis(1,1-dimethylethyl)-4-hydroxy- N-methyl-benzamide or 3,4-dichloro-N-methylbenzeneacetamide, or A represents 3,4-dichloro-N-methylbenzeneacetamide and B represents methyl-(2-phenylethyl)-amino or (2-furylmethyl)-methylamino or 4-(2-methoxyphenyl)-1-piperazinyl,  or one of R6 and R7 represents H and the other represents Cl, B represents pyrrolidine and A represents N-methyl-3-nitrobenzeneacetamide, in all their stereoisomeric forms, their hydrates and their salts as well as their preparation and their application as medicaments.