baber/WOPTO huggingface dataset:
Patent EP-0804613-B1 (EP)
Inventor: KIMCHI ADI
IPC: C12Q1/68
Filed: 1994-10-12
Granted: 2005-03-23
Abstract: The present invention is based on the pioneering finding that inhibition of expression of certain genes counteracts the cytokine-induced cell death. As long as these genes function normally, cytokine induces cell death; once the expression of said genes is inhibited, the cytokine-induced cell death is inhibited. Its follows therefrom that the normal expression is cytokine-induced cell death. In HeLa cells IFN-gamma induces a biphasic process, which comprises an initial cytostatic phase and a subsequent cytotoxic phase (programmed cell death). The novels genes discovered in accordance with the present invention were found to affect only the later, cytotoxic phase. These genes, referred to as "DAP" (death-associated protein) genes, include DNA molecules which comprise a coding sequence encoding the expression products of the DAP genes or expression products having a similar biological activity.
Patent EP-0740585-B1 (EP)
Inventor: GUTSCH ANDREAS
IPC: B03C3/41
Filed: 1995-01-04
Granted: 1998-08-05
Abstract: An apparatus (10) to carry out a process, in particular for the electrically induced agglomeration of gas-borne particles, contains a closed flow duct (12) through which is directed an aerosol containing particles (14). For the purpose of the bipolar charging of the aerosol, at least one electrode pair (20, 22) is arranged in the flow duct (12), the electrode (20) being wired, so as to be ungrounded, to the negative pole of a current source, the strength of which is sufficient to produce a corona discharge between the electrodes (20 and 22). The electrodes (20 and 22) of each electrode pair are designed to be needle-shaped and are arranged to be insulated with respect to the flow duct walls, such that their tips (26) are disposed opposite each other. By use of the apparatus (10), it is possible to charge the aerosol which is directed through the flow duct (12) at least virtually symmetrically bipolarly, without any substantial particle deposition in the region of the electrodes (20) and (22) or in the flow duct (12).
Patent EP-0748295-B1 (EP)
Inventor: KRAMER MARK G
IPC: A62D3/00
Filed: 1995-02-17
Granted: 1999-12-01
Abstract: A process for stabilizing metals in ash to prevent leaching of the metals is disclosed. The pH of an aqueous slurry of ash is reduced to less than 5 in the presence of an iron salt. The pH-reduced slurry is then treated with an organo sulfur containing compound and an alkaline earth metal oxide or hydroxide in specific weight proportions relative to the iron salt and to each other.
Patent EP-0750667-B1 (EP)
Inventor: KOHNERT ULRICH
IPC: C12N9/64
Filed: 1995-03-13
Granted: 1998-12-23
Abstract: PCT No. PCT/EP95/00926 Sec. 371 Date Sep. 13, 1996 Sec. 102(e) Date Sep. 13, 1996 PCT Filed Mar. 13, 1995 PCT Pub. No. WO95/25168 PCT Pub. Date Sep. 21, 1995Process for purifying serine proteases from a protein mixture by binding the serine protease to an immobilized polypeptide with the activity of an inhibitor DE-3 from Erythrina caffra, removing unbound components from the protein mixture, detaching the serine protease from the inhibitor and separating the immobilized inhibitor from the soluble serine protease and isolating serine protease which is characterized in that a polypeptide is used as the polypeptide which is the product of a prokaryotic or eukaryotic expression of an exogenous nucleic acid. This inhibitor is distinguished by an improved specific activity and is particularly suitable for the purification of plasminogen activators such as tissue plasminogen activators (t-PA and derivatives).
Patent EP-0779300-B1 (EP)
Inventor: TSUJI SUGURU
IPC: C08F236/12
Filed: 1995-06-07
Granted: 1998-12-23
Abstract: Copolymère de diènes insaturé conjugué à du nitrile, produit par copolymérisation des comonomères en présence d'un initiateur à radicaux libres, à l'aide d'un modificateur de poids moléculaire contenant un composé alkylthiol C12-C16 pourvu d'au moins trois atomes de carbone tertiaires et d'un atome de soufre directement lié à l'un au moins des atomes de carbone tertiaires, et qui possède une viscosité Mooney de 15 à 150, un taux de nitrile insaturé lié de 10 à 60 % du poids et une largeur de répartition de la composition du nitrile insaturé (ΔAN) de 3 à 20. Le copolymère est produit par démarrage de la copolymérisation en présence d'une partie des copolymères et addition du reste des comonomères au cours de la réaction. Il est utilisé en combinaison avec un vulcaniseur à base de soufre.
Patent EP-0770142-B1 (EP)
Inventor: PANDIAN SITHIAN
IPC: C12Q1/68
Filed: 1995-06-27
Granted: 2000-01-12
Abstract: The present invention provides a method for simplifying and significantly enhancing the sensitivity of nucleic acid hybridization assays. A method is described whereby a single-stranded primary nucleic acid sequence that includes a region of sequences complementary to a single-stranded target nucleic acid sequence is hybridized to the target molecule. Stability of the double-stranded complex thereby formed can be enhanced by using RNA as the probe if DNA is the target or DNA as the probe if RNA is the target. The probe-target complex is subsequently immunocaptured for detection. After washing away extraneous material, a secondary nucleic acid sequence containing many repeating sequence units is hybridized to the probe component of the immobilized probe-target complex. Detection occurs following hybridization of many labelled nucleic acid sequence probes to each of the repeating sequence units of a nucleic acid amplification probe. Thus, attachment of multiple labelling probes to an amplification probe that is hybridized to an immobilized probe-target complex, provides a simplified method for amplifying the detection signal and therefore the sensitivity of nucleic acid hybridization assays.
Patent EP-0839264-B1 (EP)
Inventor: HOFMANN LOTHAR
IPC: F01N3/20
Filed: 1995-09-12
Granted: 1999-12-01
Abstract: Nitrogen oxides emitted by an internal-combustion engine operated with excess air are normally converted by the method of selective catalytic reduction by bringing the nitrogen oxides, together with ammonia, into contact with a selective catalyst. Due to the dangers associated with the use of ammonia, in a motor vehicle ammonia should only be carried in the form of a substance which liberates ammonia, generally an aqueous urea solution. A method and a device for introducing liquid into an exhaust-gas purification system according to the invention avoids frost damage to sections of the system during shutdown times and permits operation of the system at temperatures below the freezing point of the reducing agent solution being used. The method and device include a (thermally insulated) reservoir for the reducing agent liquid and a liquid supply line which is connected thereto and terminates in an outlet opening for the liquid. The reservoir and the liquid supply line can be heated. Furthermore, a heater is provided for liquefying a starting volume which is small as compared with the volume of the reservoir. The liquid supply line may also have a back-flush valve to which a gas that is under pressure can be applied. The supply line can consequently be blown free.
Patent EP-0794902-B1 (EP)
Title: Method and device for removing oxygen from the headspace of a package
Inventor: HUGELSHOFER WILLY
IPC: B65B31/04
Filed: 1995-12-05
Granted: 1999-04-07
Abstract: PCT No. PCT/CH95/00290 Sec. 371 Date Aug. 22, 1997 Sec. 102(e) Date Aug. 22, 1997 PCT Filed Dec. 5, 1995 PCT Pub. No. WO96/17775 PCT Pub. Date Jun. 13, 1997Aseptic filling and sealing of packages with a food product is carried out in compartments which contain an atmosphere of sterile air and which contain devices for filling and sealing packages and a transporter device for transporting the packages through the compartments for the filling and sealing operations. Headspace sterile air is removed and displaced from the packages by injection of nitrogen into the packages from a nozzle which is at a fixed position and which directs the nitrogen at an angle with reference to a vertical perpendicular to the horizontal package transport direction and counter to the transport direction.
Patent EP-0775439-B1 (EP)
Inventor: JIMENEZ COLLADO JUAN
IPC: A01N1/00
Filed: 1995-12-19
Granted: 2003-01-22
Abstract: The compositions for the preservation of organic tissues are comprised of a mixture from 12 to 70 % of at least one dialkyl (C1-C6)-ketone peroxide, from 10 to 15 % of glycerine, from 10 to 70 % of at least one alcohol and, optionally, from 0 to 10 % of a complementary marking, coloring and/or aromatic agent. Said compositions may be mixed with other appropriate agents or diluents, and can be applied especially to the preservation of tissues of all types, of human or origin, preferably by embalming or immersion.
Patent EP-0797501-B1 (EP)
Inventor: SATO SHINOBU
IPC: B60R13/04
Filed: 1995-11-03
Granted: 2000-08-02
Abstract: The present invention provides a molding tool (1) for sealant and a sealing method using the molding tool whereby the outer surface of the sealant is formed in good shape without increasing the number of parts and working steps. Ater the sealant (120) formed of resin covering a projecting or recessed part of a jointed part (107) of members and formed of a resin tightly sealing the jointed part is arranged at the jointed part, the molding tool (1) forms the outer surface (122) of the sealant (120). The molding tool (1) is provided with a main body having a molding surface (11) which extends along the jointed part, covering at least the outer surface (122) of the sealant (120), to be in touch with the outer surface of the sealant thereby to mold the outer surface, and a pressing member (50) set at a surface of the main body confronting the molding surface and pressing the main body towards the jointed part thereby to press the molding surface to the outer surface of the sealant.
Patent EP-0725001-B1 (EP)
Inventor: BERGMANN ERHARD DR
IPC: B62D5/32
Filed: 1996-02-01
Granted: 1998-04-29
Abstract: The hydraulic servo steering system has a servo pump (2) supplying the steering control valve (14) via a variable flow resistance (19). The steering cylinder (8) is linked to the control valve by parallel ducts (17) each with variable flow resistances, and by a shunt (24) in series with a control valve (25) and a fixed flow resistance. If the servo force fails the steering is manual, with the main control valve (14) acting as a hydraulic pump. With servo failure the shunt is blocked and the servo feed isolated. The control valve operates as a hydraulic pump, with a different ratio i.e. the steering wheel has to be turned by at least twice as much as for servo steering, for the same steering deflection.
Patent EP-0781856-B1 (EP)
Inventor: ISHIKAWA YOSHITAKA
IPC: F27B7/33
Filed: 1996-12-11
Granted: 2000-08-23
Abstract: In a method of recycling iron and steel industry waste (1-1, 1-2) by processing the waste (1-1, 1-2) as an object substance by the use of a rotary kiln (7), the object substance is changed into a valuable material while the object substance travels within the rotary kiln (7) from an upstream side to a downstream side. The object substance is heated on the upstream side of the rotary kiln (7) within a reducing atmosphere to be reduced and molten into a reduced and molten product. The reduced and molten product is quickly sent to the downstream side without being adhered to an internal wall of the rotary kiln (7). The valuable material is extracted from the reduced and molten product which may be directly discharged out of the rotary kiln or which may be discharged after the reduced and molten product is once kept in a basin formed in the vicinity of the downstream side of the rotary kiln (7). <IMAGE>
Patent EP-0734781-B1 (EP)
Inventor: DE LAFORCADE VINCENT
IPC: B65D83/14
Filed: 1996-03-29
Granted: 2002-08-28
Abstract: The distributor (5) is secured to the upper part of the containers (1). It comprises, for each container, a product inlet channel (13) and a spray nozzle (16). The two spray nozzles are located on either side and orientated in convergent directions. The distributor has a mounting (6) for fixing to the containers and movable parts (7) pivoted on the mounting. The product inlet channels and nozzles are arranged on this mounting. The movable part is pivoted by a long hinge formed from a thin band. Each movable part has nozzle reception zones at the end of the channels. Each of these zones has the form of an annular hub around which is an annular space into which the inlet channel discharges.
Patent EP-0769567-B1 (EP)
Title: Process for coating a sheet
Inventor: GUESDON PHILIPPE
IPC: C23C24/10
Filed: 1996-10-01
Granted: 2000-01-12
Abstract: A metal coating still in the liquid state is treated by projecting powder onto it. The powder is produced by atomisation and the agglomerated particles produced resemble the elementary grains contained in the agglomerated particles. The average size of the particles is greater than the thickness of the liquid coating.
Patent EP-0830107-B1 (EP)
Inventor: DAROUICHE RABIH O
IPC: A61F2/06
Filed: 1996-04-22
Granted: 2004-08-18
Abstract: Cette invention concerne un implant médical non métallique imprégné d'un agent antimicrobien, tel qu'un cathéter, ainsi qu'un procédé permettant d'imprégner un implant médical non métallique d'un agent antimicrobien. Le procédé de fabrication de cet implant imprégné consiste à élaborer tout d'abord une composition antimicrobienne ayant une concentration efficace suffisante pour empêcher la croissance d'organismes, tels que staphylocoques, autres bactéries Gram positif, bacilles Gram négatif et Candida, puis à appliquer la composition antimicrobienne à au moins une partie de l'implant médical dans des conditions permettant à cette composition antimicrobienne de pénétrer dans la matière de l'implant médical. On obtient la composition antimicrobienne en dissolvant un agent antimicrobien dans un solvant organique et en ajoutant à cette composition un agent pénétrant puis un agent d'alcalinisation. De préférence, on chauffe cette composition antimicrobienne à une température comprise entre environ 30 °C et 70 °C avant de l'appliquer à l'implant médical de façon à accroître l'adhésion de l'agent antimicrobien à la matière de l'implant médical. Une fois que l'on a extrait l'implant imprégné de la solution antimicrobienne, on laisse sécher ledit implant imprégné puis on le rince avec un liquide et on le presse pour éliminer les dépôts granuleux excédentaires et assurer à l'implant imprégné une uniformité de couleur.
Patent EP-0839304-B1 (EP)
Inventor: ENGELBREKTSSON ANDERS
IPC: F24H9/12
Filed: 1996-06-25
Granted: 2001-08-29
Abstract: A distributor (7) in a single-pipe system (1, 2) in a heating or cooling apparatus has a feed pipe (3), a return and bypass pipe (4), radiators or cooling elements (5), valves (6) for the latter, and a housing (8) with an axially through-going conduit (9), one end of which forms a return inlet (10), and to which are laterally connected a return outlet (11), a feed inlet (12) and a feed outlet (13). Through the other end of said conduit (9) is inserted a control spindle (17, 21) having a cone (18) for throttling or shutting off said return inlet (10) against a seat (19) in said housing (8). According to the invention, said spindle (17, 21) is provided with a throttling cone (22) acting on a surrounding seat (23) being a circular-cylindrical restriction of said housing (8), which restriction constitutes a bypass of said system jointly with said feed inlet, said return outlet and portions of said conduit interconnecting same.
Patent EP-0839194-B1 (EP)
Inventor: CONSEILLER EMMANUEL
IPC: A61K31/70
Filed: 1996-07-17
Granted: 2006-04-26
Abstract: Proteins derived from the product of tumor suppressor gene p53 and having enhanced functions for therapeutical use are disclosed. The proteins advantageously have enhanced tumour suppressor and programmed cell death inducer functions, particularly in proliferative disease contexts where wild-type p53 protein is inactivated. Nucleic acids coding for such molecules, vectors containing same, and therapeutical use thereof, particularly in gene therapy, are also disclosed.
Patent EP-0868431-B1 (EP)
Inventor: DJAVAKHIA VITALI G
IPC: A01N63/50
Filed: 1996-08-02
Granted: 2004-12-29
Abstract: An MF2 protein having the amino acid sequence depicted in SEQ. ID. NO. 2, itself or as a part of any larger protein, or a functional derivative thereof having antiviral and/or antifungal activities, which protein is derivable from Bacillus thuringiensis. The invention also concerns a method for isolating and purifying the protein from bacterial cells expressing said protein, recombinant expression of the MF2 gene in a host cell, and the use of said protein as plant protectant.
Patent EP-0883691-B1 (EP)
Inventor: HOCH JAMES A
IPC: G01N33/15
Filed: 1996-09-12
Granted: 2004-11-17
Abstract: The present invention relates to screening methods for the identification of compounds and compositions useful as novel antibiotics and antibacterial agents. In particular, the present invention relates to methods utilizing two-component regulatory switches, for example, those comprising a prokaryotic enzyme such as histidine protein kinase that is activated to autophosphorylate by a signal transduction mechanism. The invention also relates to methods of identifying inhibitors of enzyme activity, particularly in bacterial cells. In particular, a high-throughput assay system useful in the large-scale screening of protein kinase inhibitors is disclosed.
Patent EP-0929714-B1 (EP)
Inventor: MAY JONATHAN
IPC: D21D5/16
Filed: 1996-10-03
Granted: 2001-09-19
Abstract: A screening device (e.g. screen plate or screen cylinder) is manufactured relatively inexpensively and easily yet has uniform screening openings (e.g. screening slots) even when of a width of less than 0.5 mm. A plurality of wires having first and second sections (the second sections having base portions and of smaller cross-section than the first sections) are mounted substantially parallel to each other, supported by at least one support bar or ring. The bars or rings have slots formed in a first side surface, and a cavity in open communication with the slots in a second side surface. The wires are fixed to the bars or rings by deforming the wires (e.g. by bending a flap, engagement by a reciprocating tool, welding, etc.) within the cavity, or by deformation of the support bar or ring in the cavity. The screen plate or cylinder is preferably used to screen or otherwise treat a cellulose pulp suspension, e.g. by subjecting the first sections of the wires to a flow of pulp with accepts passing through the screening openings.
Patent EP-0856012-B1 (EP)
Title: Suppression de fines formees au cours du procede de polymerisation de l'ethylene en lit fluidise
Inventor: WONDERS ALAN GEORGE
IPC: C08F210/16
Filed: 1996-10-15
Granted: 2002-04-03
Abstract: La présente invention a pour objet un procédé permettant de réguler ou de réduire la quantité de fines en poudre présentes dans un reacteur à lit fluidisé pour polyéthylène. Ce procédé utilise des hydrocarbures inertes lors de la réaction de polymérisation, ainsi que les oléfines réactives. La réduction de fines en poudre apporte des avantages importantes dans la mise en oeuvre du procédé en lit fluidisé, notamment une réduction de la formation d'agglomérats en poudre dans le réacteur et de l'encrassement de l'installation dans le flux de gaz de recyclage.
Patent EP-0801635-B1 (EP)
Inventor: YANG ALAIN
IPC: C03C25/14
Filed: 1996-11-05
Granted: 2003-07-02
Abstract: A method for forming mineral fibres by pouring a molten material onto the circumference of centrifuging wheels having substantially horizontal axes, whereby the fibres are centrifugally formed then thrown in a direction substantially parallel to the axis by a main gas flow over at least part of the wheel circumference. An auxiliary gas flow is generated in substantially the same direction as the main gas flow, a liquid binder is sprayed onto the fibres, and the auxiliary gas flow consists of individual streams of which some, in particular, are rotating. Part of the liquid binder may be fed into the rotating streams. In the device for carrying out the method, secondary blowing nozzles around the fiberising machine comprise rotary guides, particularly helical rods or worms. An enhanced distribution of the binder throughout the fibres may be achieved.
Patent EP-0870047-B1 (EP)
Inventor: USTAV MART
IPC: A01K67/027
Filed: 1996-12-27
Granted: 2008-08-06
Abstract: The invention relates to a recombinant vector for stable persistence of erogenous DNA in a eukaryotic host cell, and the uses of the recombinant vector for long-term stable production of a gene product in the host cell, the vector including the minimal origin of replication of papillomavirus and the minichromosomal maintenance element of papillomavirus.
Patent EP-0785123-B1 (EP)
Inventor: FREDERICH FRITZ DR-ING
IPC: B61F3/12
Filed: 1997-01-11
Granted: 2001-04-25
Abstract: The method for obtaining and processing data, which is used for the control or regulation of vehicles moved along a specified course. The pivoting part between the vehicles connected coupled or jointed with each other, are scanned force-free by sensors. The signal so obtained after corresp. processing is supplied to a control or regulating system as data, for altering the angle of incidence of the vehicle. The position of the wheels of a vehicle to the travel edges of the rails is scanned. The signals so obtained, after suitable preparation are supplied to a controlling or regulating system, as data, for the alteration of the incidence angle of the chassis.
Patent EP-0773387-B1 (EP)
Inventor: MOELLER FRANK
IPC: F16H47/04
Filed: 1993-10-06
Granted: 2001-08-29
Abstract: A controllable four branch differential gear (500) comprising,     a carrier (530), acting as a first element,   a plurality of first planet gears (531),   a plurality of second planet gears (532), the carrier supporting (530) at least the second planet gears (532),     an annulus (540) acting as a second element, a first sun gear (536), acting as a third element, in mesh with the first planet gears (531), each second planet gear (532) being in mesh with a first planet gear (531) and with the annulus (540), and a second sun gear, acting as a fourth element, in mesh with the second planet gear (532).
Patent EP-0800917-B1 (EP)
Inventor: LIPPOLD ANDREAS
IPC: B41F35/04
Filed: 1997-04-02
Granted: 1999-08-25
Abstract: The cleaning method uses a cleaning fluid fed to at least one washing device (10), e.g. a washing roller or a washing cloth, with the dirty cleaning fluid collected and treated to allow it to be recycled. A vegetable-based cleaning fluid can be used with treatment via gravitational sedimentation for separation into 3 parts comprising suspended solids, a mixture of the cleaning fluid and water and water. At least 2 sedimentation devices (12,16) can be connected in series.
Patent EP-0813865-B1 (EP)
Inventor: FISCHER WILFRIED DR
IPC: A61K9/70
Filed: 1994-04-20
Granted: 2001-09-19
Abstract: Active substance-contg. plaster comprises a carrier and a matrix of a single polymer, and contains vitamin E (or a vitamin E deriv.) and at least one active agent.
Patent EP-0816163-B1 (EP)
Inventor: SUROT PATRICK
IPC: B60N2/28
Filed: 1997-06-20
Granted: 2003-04-23
Abstract: The child bucket seat (2) which is fixed onto a vehicle seat (4) has two side chassis parts (40) mounted either side it on upper (41) and lower (42) axes. These define two armrest frames which pivot between close together and separated positions. Pivoting of the two chassis side parts is controlled simultaneously by a single knurled nut (52) mounted on the front (5a) of the seat (5). The control acts on a rotating plate connected to two control rods which are themselves connected to the side chassis. The control is rotated by a screw which causes rotation of a toothed wheel fixed to the rotating plate.