baber/WOPTO huggingface dataset:
Patent NZ-569949-A (NZ)
Title: Sublingual fentanyl spray
Inventor: KOTTAYIL S GEORGE
IPC: A61K9/28
Filed: 2007-01-25
Abstract: A sublingual fentanyl formulation is disclosed, which comprises discrete liquid droplets of an effective amount of fentanyl, a pharmaceutically acceptable salt thereof, or functional derivative thereof; in a pharmaceutically acceptable liquid carrier; said droplets having a mean diameter of at least about 10 microns. Said formulation may further comprise an organic solvent selected from ethanol, propylene glycol, polyethylene glycol, labrosol, labrafil, and transcutol, wherein said fentanyl, pharmaceutically acceptable salt thereof, or functional derivative thereof is dissolved in said organic solvent. . Said formulation may also comprise triacetin as an absorption enhancer.
Patent NZ-574979-A (NZ)
Title: Compositions and methods using anti-cs1 antibodies to treat multiple myeloma
Inventor: AFAR DANIEL
IPC: A61K33/243
Filed: 2007-08-07
Abstract: The use of HuLuc63 that is a humanised antibody having a heavy chain variable region corresponding to SEQ ID NO: 5 and a light chain variable region corresponding to SEQ ID NO: 6 for treating multiple myeloma. The HuLuc63 is administered sequentially or co-administered with dexamethasone, or dexamethasone and thalidomide.
Patent NZ-575344-A (NZ)
Title: Fishing line bite detector device
Inventor: BAKER MARK ROBERT
IPC: A01K91/06
Filed: 2009-03-05
Abstract: A fishing line bite detector device is disclosed. The device includes a rod-data-collector for use with a fishing rod and a hand-remote operatively connected together. The hand remote in use can be held separately from the rod data collector. The rod-data-collector and hand-remote include visual means, audio means, power means and recharging system (IPT), wireless communication means (RF),buttons for adjustability of rod-data-collector, programming means via software to control responses, a microprocessor to integrate device features and control software. The rod-data-collector has a real time data collecting means which is in the form of a solid state accelerometer, is used to relay real time data to the microprocessor which communicates said responses to the hand-remote which is adapted to receive such a signal and alert a user that a bite has been detected.
Patent NZ-582529-A (NZ)
Title: Lantibiotics from bifidobacterium longum and uses thereof
Inventor: O'SULLIVAN DANIEL J
IPC: A01N63/50
Filed: 2008-07-18
Abstract: Disclosed are isolated lantibiotics that inhibit Gram negative and Gram positive microbes. The lantibiotic includes an amino acid sequence, wherein the amino acid sequence of the compound and the amino acid sequence of SEQ ID NO:21 or SEQ ID NO:22 have at least 80% identity. The lantibiotics have the characteristic of inhibiting growth of a Gram negative microbe in conditions that do not damage the outer membrane of the Gram negative microbe.
Patent NZ-584120-A (NZ)
Title: Anti-asphyxia and back flow prevention valve between mask elbow and frame
Inventor: GING ANTHONY MICHAEL
IPC: A61M16/20
Filed: 2004-12-22
Abstract: A respiratory mask assembly includes a frame and an elbow 16 provided to the frame. The inlet 74 of the elbow receives breathing gas supplied under positive pressure for breathing by the patient. A valve 34 is provided between the elbow and the frame and is configured to allow breathing of ambient air and to prevent back flow of gas to the inlet conduit of the elbow in the event that the pressurised breathing gas cannot be supplied to the inlet of the elbow.
Patent NZ-592288-A (NZ)
Title: Antiprolactinic veterinary composition for ruminants
Inventor: LAGARDE ANOUCK
IPC: A61K31/48
Filed: 2009-10-07
Abstract: 592288 Disclosed is the use of a veterinary composition comprising at least one compound agonist of dopamine receptors for inducing the reduction antiprolactinic of lactation of ruminants and promoting mammary involution, wherein said antiprolactinic compound agonist of dopamine receptors is selected from ergoline-derived dopamine receptor agonists chosen from amongst cabergoline, metergoline, lisurdine, bromocriptine, or ergometrine, and/or non ergoline-derived dopamine receptor agonists chosen from amongst ropinirol, pramipexole, rotigotine, or quinagolide.
Patent NZ-594298-A (NZ)
Title: Molecularly imprinted polymers
Inventor: SCHWARZ LACHLAN
IPC: C08F26/06
Filed: 2010-01-29
Abstract: 594298 Disclosed is a molecularly imprinted polymer (MIP) imprinted with (E)-5-[(4-hydroxy-phenylimino)-methyl]-benzene-1,3-diol or 3,5-dihydroxy-N-(4-hydroxyphenyl)benzamide, wherein said MIP comprises a polymerised monomer. Also disclosed is a method of extracting resveratrol from a sample, said method comprising exposing the sample to a MIP imprinted with (E)-5-[(4-hydroxy-phenylimino)-methyl]-benzene-1,3-diol or 3,5-dihydroxy-N-(4-hydroxyphenyl)benzamide.
Patent NZ-594724-A (NZ)
Title: Device assisted service profile management with user preference, adaptive policy, network neutrality, and user privacy
Inventor: RALEIGH GREGORY G
IPC: H04W4/24
Filed: 2010-01-15
Abstract: 594724 A method for applying a control policy performed by a wireless end-user device and the end-user device are disclosed. The end device comprises one or more modems for enabling the end-user device to communicate over at least a first wireless access network and a second wireless access network; a user interface; memory and one or more processors. The memory is configured to store a control policy configured at least to assist in applying a first control to a first set of one or more data communications. The first set of one or more data communications is attempted, sent, or received by the end-user device over the first wireless access network. The first set of one or more data communications are associated with a first application of two or more applications on the end-user device. The first control is different from a second control applied to a second set of one or more data communications. The second set of one or more data communications is attempted, sent, or received by the end-user device over the second wireless access network. The second set of one or more data communications is associated with the first application. The one or more processors are configured to obtain a first user input through the user interface, determine at least an aspect of the control policy using the first user input, identify the first set of one or more data communications in data traffic and apply the control policy to the first set of one or more data communications identified in the data traffic, thereby at least assisting in applying the first control to the first set of one or more data communications.
Patent NZ-595246-A (NZ)
Title: Onboard unit and method for charging occupant number-dependent tolls for vehicles
Inventor: KARNER GEORG
IPC: G07B15/02
Filed: 2011-09-16
Abstract: An onboard unit (12) and a method for charging an occupant number-dependent toll for vehicles in the context of a road toll system is disclosed. The onboard unit (12) comprises a Doppler radar or UWB impulse radar (13) and an evaluation device (19). The Doppler radar or UWB impulse radar (13) is directed at the vehicle interior for measuring movements and generating at least one measurement signal representing these movements. The evaluation device (19) detects signal patterns in the measurement signal that are typical for heart or respiratory activity of an occupant and counts those signal patterns which occur simultaneously at an observation time to provide a count value, thereby calculating toll data as a function of that count value.
Patent NZ-595495-A (NZ)
Title: Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them
Inventor: GRAY KEVIN A
IPC: A23L11/20
Filed: 2006-12-08
Abstract: Disclosed is an isolated, synthetic or recombinant nucleic acid comprising a nucleic acid sequence having at least 98%, 99%, or more or complete (100%) sequence identity to SEQ ID NO: 33, as defined in the specification. The disclosed nucleic acid encodes a polypeptide having a cellobiohydrolase I (CBH I) activity.
Patent NZ-596452-A (NZ)
Title: Detection of sleep condition
Inventor: RAMANAN DINESH
IPC: A61M16/00
Filed: 2010-07-14
Abstract: 596452 A method and apparatus for determining a sleep quality index is disclosed. The method comprises the following steps: (a) receiving a signal representing a measure of respiratory flow; (b) determining, with a processor, a plurality of respiratory characteristics from the signal representing the measure of respiratory flow; (c) determining a sleep state measure substantially based on the plurality of respiratory characteristics; (d) determining a sleep stability measure from the plurality of respiratory characteristics; (e) determining a sleep quality index from the sleep state measure and the stability measure; and (f) indicating sleep quality with the sleep quality index.
Patent NZ-596988-A (NZ)
Title: Preparation of nalmefene hydrochloride from naltrexone
Inventor: DE FAVERI CARLA
IPC: C07D489/08
Filed: 2010-05-21
Abstract: Disclosed is a method for preparing nalmefene from naltrexone in a Wittig reaction wherein 2-methyltetrahydrofuran (MTHF) is used both in the formation of a phosphorous ylide and in the subsequent reaction between said ylide and naltrexone.
Patent NZ-608116-A (NZ)
Title: Triazine-oxadiazoles
Inventor: BARKER OLIVER
IPC: A61K31/53
Filed: 2011-09-13
Abstract: The invention relates to new derivatives of formula (I), wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of chronic pain.
Patent NZ-610140-A (NZ)
Title: Micro-devices for disease detection
Inventor: DU XUEDONG
IPC: G01N33/52
Filed: 2011-10-05
Abstract: Disclosed is a micro-device comprising a piezo-electric material, an electrically conductive material and a material that is neither piezo-electric nor electrically conductive. Part of the piezo-electric material forms a probe with a supporting point in the micro-device, wherein the probe is formed only by the part of the piezoelectric material. The piezo-electric material is placed between the electrically conductive material and the material that is neither piezo-electric nor electronically conductive. A portion of the probe extends out of the supporting point and the portion is substantially free and surrounded, without contact, by other materials in the micro-device. The micro-device is capable of detecting, at a microscopic level, a property of a biological subject to be detected. Methods of fabricating the micro-device by deposition and patterning of the materials are also disclosed.
Patent NZ-613971-A (NZ)
Title: Apparatus and method for isolating leukocytes and tumor cells by filtration
Inventor: SINGH SHARAT
IPC: G01N33/49
Filed: 2012-02-16
Abstract: Disclosed is an apparatus for isolating and separating leukocytes from red blood cells in a whole blood sample, the apparatus comprising: a filtration device comprising an upper chamber, which is a cylindrical tube, a lower chamber, which is a cylindrical tube, and one or more stacked filter membranes between the upper and lower chambers, wherein the one or more stacked filter membranes are capable of retaining the leukocytes, wherein the inner diameters of the upper and lower chambers are similar as to create a cylindrical tube which allows liquids to pass there through, wherein the one or more stacked filter membranes is placed between screw threads of the upper chamber and lower chamber, which chambers are securely attached together; and a collection tube for collecting red blood cells from the whole blood sample, wherein the filtration device is placed on top of the collection tube, and wherein the red blood cells are separated from the leukocytes and collected in the collection tube following centrifugation. Also disclosed is a method for preparing a lysate of leukocytes from a whole blood sample by use of the apparatus.
Patent NZ-618261-A (NZ)
Title: Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives
Inventor: KRAYNOV VADIM
IPC: C07D417/12
Filed: 2012-05-24
Abstract: The disclosure relates to non-natural amino acids and dolastatin analogs (formula (I)) that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The dolastatin analogs can include a wide range of possible functionalities, but typically have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid dolastatin analogs that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such dolastatin analogs. Further disclosed are methods for using such non-natural amino aciddolastatin analogs and modified non-natural amino acid dolastatin analogs, including therapeutic, diagnostic, and other biotechnology use.
Patent NZ-619238-A (NZ)
Title: Use of aldehyde scavengers in interior building products
Inventor: LU RUNHAI
IPC: C09D7/65
Filed: 2012-07-17
Abstract: Provided is a coating for application to the surface of an interior building product comprising a resin formulation, preferably including a melamine formaldehyde resin, and an aldehyde scavenger selected from the group consisting of: tetraethylene pentamine, propionamide, caprolactam, ammonium hydroxide, sodium bisulfate, sodium metabisulfite, ammonium primary phosphate, ammonium secondary phosphate, a combination of ammonium primary phosphate and ammonium secondary phosphate, a combination of ammonium primary phosphate, ammonium secondary phosphate and a sulfite, a polyvinyl alcohol; adipic dihydrazide, and a combination of a polyvinyl alcohol and adipic dihydrazide.
Patent NZ-625215-A (NZ)
Title: Peptide analogs for treating diseases and disorders
Inventor: MEHTA NOZER M
IPC: C07K5/00
Filed: 2012-11-02
Abstract: Disclosed is a peptide having a sequence selected from SEQ ID NO:12 (AcCSNLSTCVLGRLSQELHRLQTFPRTDVGANTAcY), SEQ ID NO:15 (AcCSNLSTCVLGKLSQELHKLQTYPRTDVGANAP-NH2) and SEQ ID NO:17 (SuccCSNLSTCVLGKLSQELHKLQTYPRTDVGANAY-NH2) and use in therapy for glycemic control.
Patent NZ-701609-A (NZ)
Title: Liquid formulation comprising propylene glycol and an inodilator
Inventor: BOVA NICHOLAS
IPC: A61P9/10
Filed: 2013-05-17
Abstract: The present invention provides a liquid formulation comprising at least 7 wt% of the total formulation of propylene glycol and: an effective amount of an inodilator selected from the group consisting of pimobendan and levosimendan and pharmaceutically or veterinary acceptable salts thereof; an angiotensin converting enzyme inhibitor selected from the group consisting of enalapril, benazepril, cilazapril, delapril, imidapril, moexipril, spirapril, temocapril, trandolapril, ramipril, quinapril, perindopril, lisinopril and pharmaceutically and veterinary acceptable salts thereof; or a combination of an inodilator selected from the group consisting of pimobendan and levosimendan and pharmaceutically or veterinary acceptable salts thereof and an angiotensin converting enzyme inhibitor selected from the group consisting of enalapril, benazepril, cilazapril, delapril, imidapril, moexipril, spirapril, temocapril, trandolapril, ramipril, quinapril, perindopril, lisinopril and pharmaceutically and veterinary acceptable salts thereof.
Patent NZ-704741-A (NZ)
Title: Neprilysin inhibitors
Inventor: FLEURY MELISSA
IPC: C07D405/12
Filed: 2013-08-07
Abstract: In one aspect, the invention relates to compounds having the formula (I): where X, Ra, Rb, R2, and R7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
Patent NZ-732885-A (NZ)
Title: A polishing pad and material and manufacturing method for such
Inventor: HEDE HANS
IPC: A44B18/00
Filed: 2015-01-28
Abstract: The invention relates to a polishing pad for polishing a surface, material for a polishing pad and a method for manufacturing material for a polishing pad. The invention aims to reduce polish usage and to improve polishing quality. A polishing pad according to an embodiment comprises a backing layer and a polishing layer made of sheep wool fibres fixed onto a surface of the backing layer, wherein the polishing layer comprises loops made of sheep wool fibres.
Patent NZ-734906-A (NZ)
Title: Non-human animal exhibiting diminished upper and lower motor neuron function and sensory perception
Inventor: Ikiz Burcin
IPC: G01N33/50
Filed: 2016-03-16
Abstract: An animal model for motor neuron dysfunction in disease, e.g., amyotrophic lateral sclerosis (ALS), comprising a genetically modified non-human animal (such as a rodent) that comprises a genetically modified endogenous DR6 locus (i) comprising a deletion of the entire DR6 coding region, or a portion thereof, and (ii) comprising a nucleic acid sequence encoding a functional DR6 signal peptide operably fused to a transmembrane domain, wherein the transmembrane protein is operably fused to a reporter protein, wherein the nucleic acid sequence is operably linked to an endogenous DR6 transcriptional regulatory sequence, wherein any polypeptide encoded by the endogenous DR6 locus lacks a functional DR6 cytoplasmic domain. The animal model exhibits normal phenotypes at birth and for a few weeks or months after birth. However, as the non-human animal ages, it develops motor neuron dysfunction that presents as one or more ALS-like symptoms, which may progress rapidly after onset. Methods of identifying candidate agents that may be used to prevent, delay or treat ALS are also provided.
Patent NZ-736517-A (NZ)
Title: Antiviral compounds
Inventor: BEIGELMAN LEONID
IPC: C07D495/14
Filed: 2014-08-19
Abstract: Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV). The new antiviral compounds are compounds of the Formula (I), or a pharmaceutically acceptable salt thereof, having the structure A–L–Y (I), wherein L is
Patent NZ-747376-A (NZ)
Title: High dose levodopa capsules for pulmonary use
Inventor: LIPP MICHAEL
IPC: A61P25/16
Filed: 2013-11-08
Abstract: Problems to be solved by the inventions are (1) freezing episodes in Parkinson’s patients related to slow-acting oral administration of levodopa - [pulmonary administration of levodopa is fast acting]; (2) formulating high-dose levodopa for inhalation - [high doses of levodopa are formulated: 15-50 milligams]; (3) optimizing the density of the levodopa inhalable powder to enable effective delivery of high doses – [working density is between about 0.02 g/cm3 to about 0.05 g/cm3]; (4) efficient emptying of the inhalable powder from the capsule to achieve maximal delivery of the high doses – [capsule shell comprises HPMC and titanium dioxide]; and (5) identifying a fast acting amorphous powder which is stable with a low electrostatic charge – [dry powder comprises from about 2% to about 8% of water by weight, and that a solution to the above-mentioned problems as fully described in the specification is a capsule for use in an inhalation device wherein said capsule is filled with a dry powder comprising levodopa, a phospholipid, and a salt, wherein the dry powder has a working density of between about 0.01 g/cm3 to about 0.1 g/cm3, and wherein the capsule’s shell comprises hydroxypropyl methylcellulose (HPMC) and titanium dioxide; wherein said capsule emits more powder comprising levodopa upon actuation of the inhalation device as compared to a capsule having a capsule shell that comprises HPMC and that is free of titanium dioxide; and wherein said dry powder comprises about 75% by weight or more of levodopa.
Patent NZ-761528-A (NZ)
Title: Tuning of a kinematic relationship between members
Inventor: CHRISTOPHER JAMES ALLINGTON
IPC: H02K49/04
Filed: 2014-08-18
Abstract: A device comprising: a first member in a kinematic relationship with a second member to form a system, the system moving within a limited range of motion and wherein the system interacts when an external energising force is imposed on the system causing the first and second members to respond due to their kinematic and dynamic characteristics and thereby creating relative motion between the first and second members; a pawl coupled to the first member said pawl moving with respect to the first member in response to a pre-determined system movement and, when the pawl moves, the pawl or a part thereof interacts with the second member, and wherein the pawl and second member comprise one or more magnets or one or more conductive members so that, as relative motion occurs between the pawl and second member, a first eddy current braking force associated with a first eddy current braking action is induced between the pawl and second member that slows relative movement between the first member and second member; and, wherein the speed and/or intensity of the first eddy current braking action imposed by the pawl on the system or a member or members thereof is controlled by the pawl rate of movement with respect to the first member and, this rate of movement is in turn governed by a second eddy current braking action induced between the pawl or a part thereof and the first member or a part thereof, a second eddy current force associated with the second eddy current braking action resisting movement of the pawl with respect to the first member.
Patent NZ-761567-A (NZ)
Title: Systems and methods for merging and compressing compact tori
Inventor: BINDERBAUER MICHL
IPC: H05H1/16
Filed: 2015-10-12
Abstract: Some previously proposed systems for pulsed fusion concepts do not facilitate a significant reduction of translation and compression losses nor an increase in driver efficiency. Disclosed herein is, a system for merging and compressing compact tori plasma comprising a central chamber, a pair of diametrically opposed formation sections, one or more diametrically opposed pairs of acceleration sections, and one or more diametrically opposed pairs of compression sections interposing the formation sections and acceleration sections adjacent to the formation sections and interposing the central chamber and acceleration sections adjacent to the central chamber. The system is configured to enable a staged symmetric sequence of compact tori formation, axial acceleration by active magnetic coils about the formation and acceleration sections, passive adiabatic compression of the compact tori within a conically constricting flux conserver of the compression sections, and magnetic compression within the central chamber.
Patent NZ-788373-A (NZ)
Title: Attractants for rodents
Inventor: GRIES GERHARD
IPC: A01P19/00
Filed: 2017-05-23
Abstract: Compositions attractive to rodents, such as mice and rats, include one or more of androstenone, testosterone, progesterone, and estrogen. The compositions can further include at least one of a lethal agent or a chemosterilant. The androstenone, testosterone, progesterone, and estrogen are isolated, purified, and/or synthetic. Devices, traps, and methods of using the compositions are also disclosed.