baber/WOPTO huggingface dataset:
Patent IL-183849-A0 (IL)
Title: Process for transition metal-catalyzed asymmetric hydrogenation of acrylic acid derivatives, and a novel catalyst system for asymmetric transition metal catalysis
Filed: 2007-06-11
Abstract: A process for transition metal-catalyzed, asymmetric hydrogenation of acrylic acid derivatives of the formula (I) in which R1 is H or an optionally substituted alkyl, aryl or heteroaryl radical, R2 is an optionally substituted alkyl, aryl or heteroaryl radical, and R3 is H or a C1-C6-alkyl radical, which comprises hydrogenating compounds of the formula (I), optionally in a solvent, in the presence of one or more hydrogen donors, using a catalyst system which comprises a transition metal from the group of ruthenium, rhodium and iridium and a combination of a chiral phosphorus ligand of the formula (II) in which Cn, together with the two oxygen atoms and the phosphorus atom, forms an optionally substituted ring having from 2 to 6 carbon atoms and R4 is an optionally substituted alkyl, aryl, alkoxy or aryloxy radical or NR5R6 where R5 and R6 may each independently be H or an optionally substituted alkyl, aryl, aralkyl or alkaryl radical, or, together with the nitrogen atom, may form a ring, and an achiral phosphine ligand of the formula (III) in which R is an optionally substituted alkyl or aryl radical, to the corresponding compounds of the formula (IV) in which R1, R2 and R3 are each as defined above, and also a novel catalyst system for asymmetric transition metal catalysis.
Patent IL-208461-A0 (IL)
Title: 3-substituted-2 (arylalkyl)-1-azabicycloalkanes and pharmaceutical compositions comprising them
IPC: C07D487/08
Filed: 2010-10-04
Abstract: The present invention relates to 3-substituted-2-(arylalkyl)-1-azabicycloalkanes, methods of preparing the compounds and methods of treatment using the compounds. The azabicycloalkanes generally are azabicycloheptanes, azabicyclooctanes, or azabicyclononanes. The aryl group in the arylalkyl moiety is a 5- or 6-membered ring heteroaromatic, preferably 3-pyridinyl and 5-pyrimidinyl moieties, and the alkyl group is typically a C1-4 alkyl. The substituent at the 3-position of the 1-azabicycloalkane is a carbonyl group-containing moiety, such as an amide, carbamate, urea, thioamide, thiocarbamate, thiourea or similar functionality. The compounds exhibit activity at nicotinic acetylcholine receptors (nAChRs), particularly the alpha7 nAChR subtype, and are useful towards modulating neurotransmission and the release of ligands involved in neurotransmission. Methods for preventing or treating conditions and disorders, including central nervous system (CNS) disorders, which are characterized by an alteration in normal neurotransmission, are also disclosed. Also disclosed are methods for treating inflammation, autoimmune disorders, pain and excess neovascularization, such as that associated with tumor growth.
Patent RO-125852-A0 (RO)
Title: Cooling fluid composition with reduced environmental impact
Inventor: NIŢĂ ION
IPC: C10M105/12
Filed: 2010-06-03
Abstract: The invention relates to a cooling fluid composition for motor vehicle engines or heat carrier for central heating installations. According to the invention, the composition consists of a mixture of 70...73% monoethylene glycol, 20...25% glycerol, 1...3% potassium 2-ethyl hexanoate and 0.1...0.3% tolytriazole as corrosion inhibitors, 4% distilled or fully demineralized water and possibly 1% colouring agent, diluted with distilled or fully demineralized water in a ratio of 1 : 1, the percentage being expressed by mass.
Patent RO-133873-A0 (RO)
Title: Nano-thread compositions based on collagen of rabbit-skin glue and anti-microbial agents and process for preparing the same
Inventor: RÂPĂ MARIA
IPC: A61L27/24
Filed: 2019-08-29
Abstract: The invention relates to an anti-microbial nano-thread composition used for manufacturing non-active bandages for treating wounds and to a process for preparing the same. According to the invention, the composition consists of 8.6...24.5% rabbit-skin glue as granules, 18.8...39.5% water, 41.7...70.6% solution of acetic acid in concentration of 40% and 2...8.3% agents with anti-microbial activity against Escherichia coli, Staphylococcus aureus and Candida albicans, the percentage being expressed by mass. The claimed process consists in electro-spinning the component mixture, with a solution flow rate of 0.4...0.9 ml/h, voltage of 22.71...24.35 kV and the distance between the needle point and the collector of 9...14 cm.
Patent AP-2001002125-A0 (AP)
Title: Controlled-rease pharmaceutical formulations.
Inventor: KING ELIZABETH
IPC: A61K9/52
Filed: 1999-10-04
Abstract: The invention provides controlled-release formulations for oral administration containing a cgmp pde-5 inhibitors. The formulations useful inter alia, in the treatment or prevention of sexual dysfunction.
Patent AU-2003900048-A0 (AU)
Title: Automated vehicle inspection system
IPC: G07B15/02
Filed: 2003-01-07
Abstract: An apparatus for the automatic inspection of a motor vehicle has an identification and psychological profiling zone, an automatic inspection zone and a manual inspection zone. A biometric and heart rate detection station and an attached console are located in zone one. Undercarriage scanning equipment and an explosives detection portal are located in zone two. The apparatus also has one or more fixed cameras, an alarm or other alerting mechanisms and a physical barrier. A vehicle detection mechanism detects the entry of a vehicle into zone two and captures an image of the vehicle number plate. When the captured biometric data and number plate data indicate that the driver is authorized to drive the particular vehicle into the secured zone, and if no abnormalities or foreign objects in the undercarriage image are detected, the driver is allowed to proceed.
Patent CU-22474-A1 (CU)
Title: Polvo extintor de incendios del tipo bce
Inventor: TORRE GONZALEZ ROBERTO DE LA
IPC: A62D1/00
Filed: 1995-03-03
Abstract: La presente invención se relaciona con la rama de la Química aplicada y en particular se refiere a una nueva composición de polvos extintores del tipo BCE, utilizado en la extinción de fuegos clases B, C y E, o sea, producidos o generados por combustibles líquidos o por sustancias gaseosas y fuegos en presencia de cables o equipos eléctricos bajo tensión. El objetivo de la invención consistió en eliminar de la composición la presencia de una sustancia fundamental; pero de alta higroscopicidad que produce alteraciones físicas en el polvo, que impiden su adecuada aplicación, por el carbonato de calcio. La esencia de la invención consiste en crear un polvo extintor donde se elimina al máximo la presencia de sustancias que por su alta higroscopicidad favorecen el apelotamiento y por tanto afectan su adecuada aplicación compuesto por carbonato de calcio y estearato de zinc para impedir el apelmazamiento. Fórmula general: Carbonato de calcio .............................. 90 - 98% Agente fluidizante ................................. 1, 2 - 5% Y antiapelmazante ................................ Como posibles campos de aplicación tenemos la extinción de todas las clases de fuegos antes mencionados.
Patent MW-2775-A1 (MW)
Title: Process for the preparation of ter-alkyl ethers
IPC: C07C41/00
Filed: 1975-05-09
Abstract: Methyl tert-butyl ether is prepared, and a stream of hydrocarbons containing isobutylene is freed therefrom, by reacting the isobutylene with methanol in a two stage process wherein, in the first stage, a stream of hydrocarbons containing isobutylene and methanol is fed to a primary reaction zone where the isobutylene and methanol partially react in the temperature range of from 50 DEG  to 90 DEG C and at a pressure of from 10 to 30 atmospheres in the presence of a catalyst to form methyl tert-butyl ether which is separated by distillation from the residue of isobutylene and methanol and all other hydrocarbons in the feed stream, and, in a second stage, the residue of isobutylene and methanol and other hydrocarbons is fed to a secondary reaction zone where the residue of isobutylene and methanol react in the vapor phase, at a temperature in the range of 60 DEG  to 100 DEG C and a pressure of from 15 to 40 atmospheres in the presence of a catalyst consisting of an acid ion exchange resin, to form the balance of methyl tert-butyl ether which is recovered by distillation to leave a balance of other hydrocarbons practically free from isobutylene.
Patent IE-910567-A1 (IE)
Title: Coated perfume particles
IPC: C11D17/00
Filed: 1991-02-19
Abstract: Perfume particles comprise perfume dispersed within certain water-insoluble nonpolymeric carrier materials and encapsulated in a protective shell by coating with a friable coating material. The coated particles allow for preservation and protection of perfumes which are susceptible to degradation or loss in storage and in cleaning compositions. In use, the surface coating fractures and the underlying carrier/perfume particles efficiently deliver a large variety of perfume types to fabrics or other surfaces.
Patent LU-71930-A1 (LU)
IPC: B60B21/10
Filed: 1975-02-27
Abstract: This disclosure relates to a pneumatic tire that is designed to be run-flat for a certain distance without destroying the remaining life of the tire as a result of injuries to the tire during its run-flat operation. The disclosure further relates to a combination of this tire with a special rim and internal lubricating means within the air chamber defined by the rim and tire. This combination further enhances the non-destructive run-flat characteristics of the tire.
Patent LU-87408-A1 (LU)
Inventor: LUC LEVEQUE JEAN
IPC: A61K31/60
Filed: 1988-12-16
Abstract: The invention relates to a composition intended for the treatment of skin ageing, containing, in a physiologically acceptable medium, at least one salicylic acid derivative corresponding to the formula: <IMAGE>  in which: R represents a saturated aliphatic chain or an unsaturated chain bearing one or more conjugated or unconjugated double bonds, it being possible for the chains to be substituted with one or more halogen atoms as well as with trifluoromethyl groups, with one or more hydroxyl groups in free form or esterified with an acid, or alternatively with a carboxyl function, free or esterified with a lower alcohol;  R' represents a hydroxyl group or an ester function of formula: <IMAGE> where R1 is a saturated or unsaturated aliphatic group.
Patent MA-24897-A1 (MA)
Inventor: KENNETH WILLIAM WILLMAN
IPC: C11D1/62
Filed: 1998-10-08
Abstract: Surfactant system mixtures of mid-chain branched primary alkyl sulfate surfactants useful in cleaning compositions, especially for lower water temperature applications, formulated with higher levels (above about 20%) of linear alkyl benzene sulfonate and low levels of cationic surfactants.
Patent MA-38169-A1 (MA)
Title: Ciclésonide pour le traitement d'une maladie des voies respiratoires chez les chevaux
Inventor: ALBRECHT BALAZS
IPC: A61P11/00
Filed: 2015-06-09
Abstract: L'invention concerne le domaine de la médecine, en particulier le domaine de la médecine vétérinaire. La présente invention concerne des glucocorticoïdes, en particulier le ciclésonide ou un dérivé pharmaceutiquement acceptable de celui-ci, pour le traitement d'une maladie des voies respiratoires chez les chevaux, telles qu'une maladie pulmonaire, de préférence l'obstruction récurrente des voies respiratoires (rao), la maladie pulmonaire obstructive associée aux pâturages d'été (spaopd), et une maladie inflammatoire des voies respiratoires (iad).
Patent MA-38495-A1 (MA)
Title: Compositions et méthodes pour le diagnostic et le traitement de cancers hépatiques
Inventor: FRENCH DOROTHY
IPC: C07K16/28
Filed: 2014-03-13
Abstract: La présente invention concerne des méthodes de traitement d'un cancer du foie à l'aide d'un inhibiteur de la signalisation notch. L'invention concerne également des compositions et des méthodes de traitement de cancers du foie.
Patent UY-26683-A1 (UY)
Title: Agentes diazabicíclicos activos en el snc
Inventor: SCHRIMPF MICHAEL R
Filed: 2001-04-25
Abstract: Compuestos de fórmula I: composiciones farmacéuticas de estos compuestos, y el uso de dichas composiciones para controlar la transmisión sináptica en mamíferos.
Patent UY-27277-A1 (UY)
Title: Método para fabricar una composición farmacéutica de dosis baja que tiene una distribución y potencia del fármaco uniformes
Inventor: GIERER DANIEL ACOTT
IPC: A61K9/20
Filed: 2002-04-30
Abstract: Se describe un método para fabricar una composición farmacéutica que tiene una distribución y potencia de fármaco uniforme, el cual utiliza dioxido de silicio para reducir la pérdida de ingredientes activo durante el proceso de fabricación . El método es particularmente útil para la fabricación de composiciones para comprimidos de baja dosificación.
Patent UY-28062-A1 (UY)
Title: Pelicula extensible de resina termoplastica, utilizable para alimento confeccionado
Inventor: FRANCESCONI LORENZO
IPC: B32B27/30
Filed: 2003-11-05
Abstract: La película está constituida por un espesor interno en polivinilcloruro (PVC) con plastificantes poliméricos, coextruido con dos delgados espesores externos de resinas sintéticas -en etileno-vinilacetato (EVA) o en poliestireno extensible (PS) o en otras materias termoplásticas - no tóxicas y aptas para obstaculizar la transmisión de partículas presentes en el PVC.
Patent UY-28072-A1 (UY)
Title: Derivados de fenil o heteroaril amino alcano
Inventor: MURATA TOSHIKI
IPC: C07D277/42
Filed: 2003-11-07
Abstract: Derivados de fenil o heteroaril amino alcano útiles como ingrediente activo de preparaciones farmacéuticas que tienen actividad antagonista del receptor IP, útiles para profilaxis y tratamiento de enfermedades asociadas con actividad antagonista del receptor IP tales como: Obstrucción de salida de vejiga, vejiga hiperactiva, incontinencia urinaria, hiperreflexia del detrusor, inestabilidad del detrusor, capacidad de vejiga reducida, frecuencia de micción, incontinencias varias, hiperactividad de la vejiga, hipertrofia prostática benigna (BPH), prostatitis, frecuencia urinaria, hipersensibilidad pélvica, uretritis, síndrome de dolor pélvico, prostatodinia, cistitis o hipersensibilidad de vejiga idiopática y para tratar el dolor inflamatorio, neuropático, agudo, crónico, dental, premenstrual, dolor visceral, de cabeza y similares; hipotensión; hemofilia y hemorragia; e inflamación; (dichas enfermedades también se alivian por el tratamiento con antagonistas del receptor IP).
Patent UY-28927-A1 (UY)
Title: Panel aislado y junta del panel estructuralmente mejorados
Inventor: SCHAFFER LISA CLEAR
IPC: E04B2/08
Filed: 2005-05-27
Abstract: Un panel aislado estructualemente mejorado y junta de panel incluyendo un panel que tiene un núcleo con paramentos cementicios en donde el borde del núcleo es acanalado y a lo largo del panel los bordes laterales se rebajan para acomodar a la columna conectora. La columna conectora se presenta en forma de "H", formada a partir de dos canales en forma de "C", cuyos canales se sellan a la vez junto con otras láminas con patas que se proyectan externamente y para uso dentro de dos de los paneles. Se divulgan estructuras de pared múltiple y detalles.
Patent UY-29791-A1 (UY)
Title: Sales novedosas de lisina de derivados de acido 4-( (fenoxialquil)tio)-fenoxiacetico
Inventor: ABDEL-MAGID AHMED F
IPC: A61P3/00
Filed: 2006-09-14
Abstract: La presente invención se refiere a una sal de lisina novedosa, composiciones farmacéuticas que las contienen y su uso en el tratamiento de trastornos y condiciones modulados por PPAR delta. La presente invención se refiere además a un proceso novedoso para la preparación de dichas sales de lisina.
Patent UY-30997-A1 (UY)
Title: Mutantes de ahas
Inventor: SINGH BIJAY
IPC: C07H21/00
Filed: 2008-04-03
Abstract: La invencion proporciona ácidos nucleicos que codifican mutantes de la gran subunidad de acetohidroxiácido-sintasa (AHAS) que comprende al menos dos mutaciones, por ejemplo mutantes dobles y triples, que son utiles para producir plantas transgénicas o no transgénicas con niveles mejorados de tolerancia a los herbicidas que inhiben la AHAS. La invencion también proporciona vectores de expresion, células, plantas que comprenden los polinucleotidos que codifican los mutantes dobles y triples de la gran subunidad de AHAS, plantas que comprenden dos o más polipéptidos de mutante unico de la gran subunidad de AHAS, y métodos para hacerlos y usarlos.
Patent UY-31567-A1 (UY)
Title: Un método mejorado de preparacion de macromonomeros de triglecéridos
IPC: C01B7/14
Filed: 2008-12-19
Abstract: invencion divulga un método de preparacion de macromonomeros etilénicamente insaturados derivados de aceites insaturados no minerales conjugados, especialmente de aceites de plantas y vegetales. Divulga los polímeros, particularmente en forma de dispersiones acuosas derivadas de los mismos y , por ultimo, adhesivos y cubiertas, especialmente cubiertas arquitectonicas, que comprenden dichos polímeros.
Patent ES-194574-A1 (ES)
Title: APARATO PARA LA EXPLORACIoN AUDITIVA DE RUIDOS EN LAS TUBERiAS DE MáQUINAS U OTRAS INSTALACIONES CON CANERiAS O TUBERiAS
Filed: 1950-09-13
Abstract: Aparato para la exploración auditiva de ruidos en las tuberías de máquinas u otras instalaciones con cañerías y tuberías, caracterizado por el hecho de que se emplea como medio de transmisión un alma de metal (acero) que está rodeada por una capa aisladora, p.ej. de goma y encerrado en un tubo flexible.
Patent ES-221596-A1 (ES)
Title: Recovery of tetracycline from fermentation broths
Filed: 1955-05-05
Abstract: Aqueous solutions of tetracycline for oral and parenteral use having a pH 3.5 to 9, and containing excess of 20 mgm./ml. tetracycline are prepared by mixing tetracycline, a non-toxic heavy metal salt, e.g. aluminium sulphate and tartaric acid or similar non-toxic sequestering agents such as citric acid, ethylene diamine, tetra-acetic acid, gluconic acid and phylic acid. Alternatively, a heavy metal salt of tetracycline may be mixed with the non-toxic sequestering agent. By heavy metal is meant any metal other than the alkali metals. Specification 770,065, [Group IV (b)], is referred to.
Patent ES-228196-A1 (ES)
Title: Improvements in or relating to expanded plastic material
IPC: C08J9/00
Filed: 1956-04-26
Abstract: A heat-expandable composition comprises a major amount of a vinyl chloride polymer, a minor amount of a butadiene-methyl methacrylate copolymer and a blowing agent. The copolymer may be produced by polymerizing a mixture of the monomers containing a major proportion, e.g. from 70-90 per cent of methyl methacrylate. The composition may contain from 20-40 parts of the copolymer per 100 parts of vinyl chloride polymer and a minor proportion, e.g. up to 10 per cent, of a plasticizer for the polymer. Specified blowing agents are sodium bicarbonate, ammonium carbonate, ammonium carbamate, diamino benzene, biuret, salts of urea with organic acids, 1,3-bis-(o-xenyl) triazene, benzene sulphonyl hydrazide, p,p1-oxybis-(benzene sulphonyl hydrazide), di-N-nitrosopentamethylene tetramine, amino-guanidine bicarbonate, alpha, alpha-azodi-isobutyronitrile and azo dicarbonamide.
Patent ES-233465-A1 (ES)
Title: Process for manufacturing dense, extra pure silicon
IPC: H01L21/205
Filed: 1957-02-07
Abstract: <PICT:0855913/III/1> <PICT:0855913/III/2> Ultra-pure silicon, which may be used for transistor manufacture, is produced by dissociation of trichlorsilane vapour in part in a first zone at 800-900 DEG C. to remove impurities and in part in a second zone at least 950 DEG C. Crude silicon, which may be produced in an electric furnace, is reacted with dry hydrochloric acid gas, and the trichlorosilane formed is purified. Dry HCl gas enters, at 6 (Fig. 1), steel tube 1 containing silicon, mixed with at least 5% copper to act as catalyst, supported on grid 2. The HCl enters very slowly, or may be diluted with H2 or N2. Resistors, an oil bath, or warm air are used to heat the reactor to 200-250 DEG C., preferably the temperature is maintained at 240 DEG C. with a temperature around the reactor of 220 DEG C. SiHCl3, which may contain 10-20% SiCl4, passes through 7 to a condenser cooled to -20 DEG C. or under pressure. The condensate is purified by distillation from first stage vessel 10 (Fig. 2), in a heating bath, through column 11, cooling control unit 12, to increase separation efficiency, and condenser 13. The impure part of the resulting condensate collects in receiver 14, but most passes to second stage vessel 15 where it is redistilled into receiver 18. The two stage distillation apparatus is made of "Pyrex" (Registered Trade Mark) glass. A non-reactive gas, e.g. A, N2, or, preferably, H2, is passed at 28 into vessel 19, to which the SiHCl3 is transferred from 18, and the mixture of H2 and SiHCl3, containing less than 20% SiHCl3, flows through 26 to quartz tube 20, part 23 of which is heated to 850 DEG C. by resistors 22, while part 24 is heated to 950 DEG C. Part of the SiHCl3 is decomposed in 23 and retains last impurities, and dense silicon is deposited in 24, while SiCl4 is withdrawn and condensed. When a layer of silicon has been formed, the SiHCl3 content of the gas may be increased to 20%. On cooling, the tube 20 breaks due to the adherent silicon layer, so surrounding tube 21 is provided through which A or H2 is passed. The recovered silicon is finally washed successively with hot hydrofluoric acid, distilled water, caustic soda solution, distilled water, hydrofluoric acid, and distilled water, and then dried. The hydrogen for diluting SiHCl3 is purified by passage through tubes packed with palladium-coated asbestos to remove oxygen, and caustic soda to remove CO2 and moisture. The gas is finally dried with magnesium perchlorate and then passes through an absorbent cotton filter.
Patent ES-265305-A1 (ES)
Title: Pressure sensitive adhesive tape
IPC: C09J7/50
Filed: 1961-03-01
Abstract: A method of rendering a flexible hydrophobic backing film of cellulose acetate-propionate or cellulose acetate-butyrate, to which pressure-sensitive film adhesives ordinarily adhere poorly, capable of forming firmly adherent bonds with a subsequently applied pressure-sensitive adhesive, includes the steps of preparing an aqueous emulsion of a polymeric alkyl acrylate, which is capable of forming a substantially tackfree film, and a rubbery material which is compatible with the pressure-sensitive adhesive which it is desired to employ, uniformly applying the emulsion on a major surface of the backing film, and heating the thus coated film, e.g. to a temperature of 170 DEG F. (77 DEG C.), for a time sufficient to evaporate the water and anchor the primer coating to the film. A pressure-sensitive adhesive is applied over the primed film. The alkyl acrylate polymer (which term includes alkyl methacrylate polymers) may be non-tacky and derived from an alcohol containing not more than four carbon atoms. The aqueous emulsion may comprise polymers of alkyl acrylates or alkyl methacrylates, or copolymers thereof with vinyl acetate or chloride, acrylic or methacrylic acid, itaconic acid or maleic anhydride, and a soft, readily deformable rubber of the same type as that contained in the pressure-sensitive adhesive, the weight ratio of alkyl acrylate polymer to rubber in the primer layer being in the range of from 0,5 : 1 to 2 : 1. The primer layer may comprise from at least 0,02, e.g. 0,2-10, parts by weight of an alkyl acrylate polymer derived from an alcohol containing not more than four carbon atoms and one part by weight of a soft readily deformable rubber, e.g. a normally tacky acrylate polymer which is compatible with the pressure-sensitive adhesive. The pressure-sensitive adhesive sheet material is capable of being wound in roll form and unwound therefrom in normal use. The rubbery material may be natural rubber, butadiene-styrene copolymer, polyisobutylene or butyl rubber. The adhesive specified contains natural rubber and terpene resin.