Patent GB-450256-A (GB)
Title: Process for the manufacture of organic mercury-silicon compounds
IPC: C07F3/10
Filed: 1935-01-12
Abstract: Organo-mercury-silicon compounds are prepared by treating soluble mercury compounds in which one valency of the mercury is directly bound to a carbon atom of an organic radicle and the other is attached to a hydroxyl or acid radicle with reactive silicon compounds, viz silicic acid, its soluble and double salts, and derivatives of silicic acid such as the halides.  A solvent or diluent is preferably employed and an inert material such as talcum and kieselguhr may be present.  The products are useful pharmaceutically and as disinfectants; also for combating insects and as seed immunizers.  Examples are given of the interaction of (1) water glass with ethylmercury nitrate, methoxyethylmercury acetate, ethoxyethylmercury acetate, hydroxypropylmercury acetate, propyloxyethylmercury acetate, cyclohexanolmethylether - mercury acetate, o - hydroxyphenylmercury chloride, p - dimethylanilinemercury acetate, ethoxyethylmercury hydroxide, methoxyethylmercury chloride and acetoxyethylmercury acetate; (2) silicon tetrachloride with ethoxypropylmercury hydroxide; (3) silicic acid, obtained by dialyzing a solution of water glass in dilute hydrochloride acid, with methoxyethylmercury hydroxide; (4) water glass with methoxyethylmercury acetate in presence of talc; (5) silicon tetra-acetate with methoxyethylmercury hydroxide or acetate; (6) a double salt prepared from aluminium sulphate and water glass with methoxyethylmercury acetate; (7) water glass with methoxyethylmercury acetate in presence of aluminium sulphate; and (8) sodium aluminium silicate with methoxyethylmercury acetate or chloride.  The Specification as open to inspection under Sect. 91 states that when the products are used as seed immunizers, their production may be allowed to take place by the action of the humidity of the soil or rain upon mixtures of the mercury and silicon compounds used as starting materials.  This subject-matter does not appear in the Specification as accepted.  Organo-mercury compounds.--Hydroxypropylmercury acetate is prepared by passing propylene into an acetic acid suspension of yellow mercuric oxide; similarly, propyloxyethylmercury acetate is formed when ethylene is passed into acetic acid and propyl alcohol containing yellow mercuric oxide in suspension, and cyclohexanolmethylether-mercury acetate when cyclohexene is stirred with acetic acid, methyl alcohol and yellow mercuric oxide.  Ethoxyethylmercury hydroxide is formed by treatment of the corresponding chloride with caustic soda in dilute alcohol. Ethoxypropylmercury chloride, obtained by passing propylene into acetic acid and ethyl alcohol containing yellow mercuric oxide in suspension, is similarly converted into hydroxide with caustic soda. Acetyloxyethylmercury acetate is prepared by introducing ethylene into a mixture of glacial acetic acid and yellow mercuric oxide.ALSO:Organo-mercury-silicon compounds, which may be admixed with inert materials, are stated to be useful as disinfectants, for combating insects and as seed immunizers.  An example is given of the preparation of a mixture of a mercury-silicon compound with talcum or kieselguhr, suitable for use as a seed immunizer, by reacting methoxyethyl-mercury acetate with water glass in aqueous solution in the presence of the solid diluent.  The Specification as open to inspection under Sect. 91 states that when the products are used as seed immunizers, their production may be allowed to take place by the action of the humidity of the soil or rain upon mixtures of the mercury and silicon compounds used as starting materials.  This subject-matter does not appear in the Specification as accepted.