baber/WOPTO huggingface dataset:
Patent NZ-228747-A (NZ)
Title: Stabilised pharmaceutical formulations comprising human growth hormone, glycine and mannitol
Inventor: PEARLMAN RODNEY
IPC: A61K9/00
Filed: 1989-04-14
Abstract: Dimer and aggregate formation in hGH formulations liable to exposure to shear surface stresses is inhibited by the inclusion of 0.1 to 5% w/v of a non-ionic surfactant such as polysorbate 80 or poloxamer 188. <IMAGE>   <IMAGE>
Patent NZ-233065-A (NZ)
Title: Hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl carbonates and pharmaceutical compositions
Inventor: GLAMKOWSKI EDWARD J
IPC: A61K31/40
Filed: 1990-03-23
Abstract: This invention relates to 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b] indol-5-ol carbonate esters of the formula <CHEM>  where R is lower alkyl, cycloalkyl, aryl, aralkyl or <CHEM> X is hydrogen or halogen; the pharmaceutically acceptable acid addition salts thereof and where applicable to the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as analgesic agents.
Patent NZ-240669-A (NZ)
Title: Open ended wrap-around carrier with article retainer flaps integral with the bottom panel
Inventor: COOPER LEONARD MICHAEL
IPC: B65D71/00
Filed: 1991-11-20
Abstract: Integral retaining means in an open-ended wrap-around carrier for preventing the spaced bottom portions of articles such as tapered tubs from engaging each other and escaping the carrier through the open end. The bottom panel (22) is comprised of inner and outer mechanically connected flaps (24, 26). The outer bottom panel flap (26) contains a retainer flap (32) at each end connected along a fold line (40) overlying the inner edge (68) of an opening (56) in the inner bottom panel flap (24). The retainer flaps (32) extend up into the interior of the carrier through the openings (56) in the inner bottom panel flap (24), and include spaced converging fold lines (50) which create angled side walls (54) for engaging the bottom portions of the articles.
Patent NZ-244390-A (NZ)
Title: Use of ranitidine bismuth sulphate and one or more helicobacter pylori inhibiting antibiotics to prepare pharmaceutical compositions
Inventor: MCCOLM ANDREW ALEXANDER
IPC: A61K45/06
Filed: 1992-09-18
Abstract: The use is described of both (i) ranitidine bismuth citrate and (ii) one or more Helicobacter pylori-inhibiting antibiotics in treating or preventing gastrointestinal disorders. Pharmaceutical compositions containing both (i) and (ii) and methods for the preparation of pharmaceutical compositions containing (i) and (ii) are also described.
Patent NZ-254417-A (NZ)
Title: Absorbent structure containing absorbent hydrogel particles, hydrogel particles of 105 micrometers or larger distributed in a primary layer
Inventor: PLISCHKE MANFRED
IPC: A61F/
Filed: 1993-06-22
Abstract: The present invention relates to absorbent structures for disposable absorbent articles containing absorbent hydrogel particles (75). More particularly, the invention relates to absorbent structures having the absorbent hydrogel particles distributed such that essentially only particles of less than 105 micrometers are distributed in a dusting layer (2), which in a disposable absorbent article is adjacent the backsheet side of the absorbent article, and particles of 105 micrometers or larger are distributed in a primary layer (1). <IMAGE>
Patent NZ-279166-A (NZ)
Title: Modified papilloma virus which does not or only minimally binds dna and virus like particles formed therefrom
Inventor: FRAZER IAN
IPC: A61K35/76
Filed: 1995-01-31
Abstract: The invention, in one aspect, is directed to a modified papilloma virus L2 protein which does not bind DNA or which has a substantially impaired ability to bind DNA compared to wild-type papilloma virus L2 protein. The invention is also directed to a method of producing one or more virus-like particles comprising a modified papilloma virus L2 protein according to the invention. The invention also resides in virus-like particles produced from this method.
Patent NZ-279439-A (NZ)
Title: Synergistic antimicrobial composition, halogenated acetophenone and organic acid derivatives
Inventor: OPPONG DAVID
IPC: A01N35/04
Filed: 1995-01-24
Abstract: Compositions for controlling the growth of microorganisms in or on a product, material or medium comprising synergistically effective amounts of halogenated acetophenones, such as 2-bromo-4-hydroxyacetophenone, and at least one organic acid, its salt or ester are disclosed. Methods to control the growth of microorganisms and prevent spoilage caused by microorganisms with the use of the compositions of the present invention are also disclosed.
Patent NZ-298384-A (NZ)
Title: Inhaler - single dose of particulate substance arranged in air flow passage
Inventor: KELDMANN ERIK
IPC: A61M15/00
Filed: 1996-01-22
Abstract: An inhaler comprises a tubular body in which an air flow passage is defined. A single dose of an active, inhaleable, particulate substance is arranged within the air flow passage and is sealed or closed in relation to the ambient atmosphere by closure means, such as removable caps, a section of the flow passage extending from a free mouthpiece end of the tubular body along a major part of the total length of the flow passage is preferably 7-35 mm<2>, for example about 20 mm<2>. The inhaler may be adapted to be used only once, and the tubular body of the inhaler may be a length of a simple tube similar to a drinking straw.
Patent NZ-314793-A (NZ)
Title: Humanised immunoglobulins; production and use to manufacture a medicament, polynucleotides and cell lines
Inventor: QUEEN CARY L
IPC: C07K16/46
Filed: 1990-01-04
Abstract: The humanized immunoglobulin having complementarity determining regions (CDR's) from a donor immunoglobulin and a heavy and light chain variable region frameworks from a human acceptor immunoglobulin heavy and light chain is claimed. The humanized specifically binds to an antigen with an affinity constant of at least 107 M-1 and no greater than about four-fold that of the donor immunoglobulin. The humanized immunoglobulin comprises amino acids from the donor immunoglobulin framework outside the Kabat and Chothia CDR's wherein the donor amino acids replace corresponding amino acids in the acceptor immunoglobulin heavy or light frameworks and the each of the donor amino acids: i) is adjacent to a CDR in the donor immunoglobulin sequence or ii) contains an atom with a distance of 4 A of a CDR in the humanized immunoglobulin.
Patent NZ-323964-A (NZ)
Title: 4,10beta-diacetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1-hydroxy-9-oxo-19-nor-cy clopropa[g]tax-11-ene-13alpha-yl
Inventor: DIDIER ERIC
IPC: A61K31/335
Filed: 1996-12-09
Abstract: 4,10Ô-diacetoxy-2ß-benzoyloxy-5Ô,20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa[g]tax-11-ene-13ß-ßyl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate dihydrate is disclosed.  Also encompassed is the preparation thereof by crystallisation from a water-alcohol or water-ketone solution.
Patent NZ-331858-A (NZ)
Title: Tetralone or benzopyranone derivatives and process for producing the same
Inventor: YOSHIHAMA MAKOTO
IPC: C07C65/40
Filed: 1998-01-28
Abstract: The present invention provides new tetralone or benzopyranone derivatives and a method for producing the derivatives useful for a therapeutic agent for preventing and/or treating hormone dependent diseases. The present invention is a new tetralone or benzopyranone derivative represented by a particular general formula (I). <CHEM> wherein R1 and R2 represent hydrogen, a hydroxy group, an alkyloxy group or an aralkyloxy group, respectively, R3- R7 represent hydrogen, a hydroxy group or a straight or branched alkyl, alkyloxy or aralkyloxy group having 1-6 carbon atoms, a halogen, an amino group or an alkylene dioxy group joined at R3 and R4, R4 and R5, R5 and R6, or R6 and R7, respectively, and A represents a methylene or oxygen. In the production, a particular tetralone or benzopyranone compound and a particular benzaldehyde compound are reacted.
Patent NZ-331933-A (NZ)
Title: Combination preparation, comprising 5-methyl-4'-trifluoromethyl-4-isoxazolecarboxanilide and n-(4-tirfluoromethylphenyl)-2-cyano-3-hydroxycrotonamide
Inventor: BARTLETT ROBERT
IPC: A61K31/42
Filed: 1997-03-07
Abstract: A solid preparation, containing 5-methylisoxazole-4-carboxylic acid-(4-trifluoromethyl)-anilide and N-(4-trifluoromethylphenyl)-2-cyano-3-hydroxycrotonic acid amide of formula I, suitable for use in the treatment of immunological conditions.
Patent NZ-332622-A (NZ)
Title: Substituted heterocyclic benzocycloalkenes having analgesic effects via delta-opiate receptors
Inventor: ZIMMER OSWALD
IPC: C07D311/58
Filed: 1998-11-03
Abstract: The present invention relates to the formula described; wherein R1 denotes OH, C1-6-alkoxy or -O(C3-7)-cycloalkyl; R2 denotes C1-6-alkyl; R3 denotes C1-6-alkyl,-(CH2)1-2-aryl,-(CH2)1-2-heterocyclyl, -CH2CH=C(R6)2, pr -CH2-(C3-7)-cycloalkyl; R4 and R5, identically to or different from each other, denote H, Cl, F, CF3, C1-6-alkyl, OH, C1-6-alkoxy. O-(C3-7)-cycloalkyl, -(CH2)0-2-aryl, -O-(CH2)0-2-aryl, a,b- or b, g-benzo which are unsubstituted, mono- or disubstituted with Cl, F, CF3, OH, C1-6-alkyl or C1-6-alkoxy or -CON(R6R7); R6 denotes H or C1-6-alkyl; R7 denotes H, C1-6-alkyl, -(CH2)0-2-aryl or CH2-(C3-C7)-cycloalkyl or R6 and R7 taken together denote (-CH2-)5-7 or (CH2)2-O-(CH2)2-; X denotes O, S, SO or SO2 Y denotes -(CH2)1-2-, -CH2-C(CH3)2- or -C(CH3)2-; Or pharmaceutically acceptable salts thereof. The underlying object of the present invention is therefore to identify substances having analgesic effect, the biological efficacy of which is brought about, having predominantly or in part, via d-opiate receptors. These requirements have been fulfilled by the substituted heterocyclic benzocyclalkene compounds of the present invention.
Patent NZ-337999-A (NZ)
Title: A stab-resisting material coated with abrasive particles such as silicon carbide, titanium carbide, alumina, tungsten carbide, titanium nitride and silicon nitride which confers stab resistance properties
Inventor: BREUKERS JOSEPH JUDITH
IPC: A41D31/00
Filed: 1998-04-03
Abstract: A stab-resisting material includes a carrier coated with solid particles, which is provided on a packet of fabrics, in which the coating on the carrier includes abrasive particles having a diameter of 0.1-3 mm, and in which the packet of fabrics is thicker than 1.5 mm. The abrasive particles may be provided on the carrier by an adhesive, which forms an elastic film after curing. In particular, a fabric made of Aramid or Nylon fibres may be used as the carrier material. The preferred adhesive is a bituminous adhesive or an adhesive with a base of polyurethane. This material is used in particular in protective clothing.
Patent NZ-504069-A (NZ)
Title: Preparing 4-dimethylamino-1-(4-amino-2-hydroxymethylphenyl)-1-(4-fluorophenyl)butan-1-ol or 4-dimethylamino-1-(4-acetylamino-2-hydroxymethylphenyl)-1-(4-fluorophenyl)butan-1-ol using Grignard reagent 4-halogen-fluorophenyl
Inventor: PETERSEN HANS
IPC: C07D307/87
Filed: 1997-11-11
Abstract: Citalopram is a well-known selective, centrally active serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor, accordingly having antidepressant activities.  A more favourable and safer procedure for manufacturing Citalopram using a more convenient starting material is disclosed. A method is outlined for the preparation of citalopram that comprises steps of: a) reacting a compound of Formula IV wherein R1 is H or C1-6 alkylcarbonyl with a Grignard reagent of 4-halogen-fluorophenyl; b) reacting the resulting compound of Formula V wherein R1 is as defined above, with a Grignard reagent of 3-halogen-N,N-dimethylpropyl-amine; c) effecting ring closure of the resulting compound of Formula VI wherein R1 is as defined above, and converting the resulting compound of Formula VII wherein R1 is as defined above, into the corresponding 5-cyano derivative, i.e.,citalopram, which is isolated as a base or a pharmaceutically acceptable salt thereof.
Patent NZ-505587-A (NZ)
Title: Apparatus for handling a container with pair of folding cranes that when retracted have upper sides that align with plane of vehicle deck
Inventor: SEPPALA TEIJO SAKARI
IPC: B60P1/64
Filed: 1999-01-07
Abstract: An  apparatus is disclosed for handling  a  container, such  as  transferring a container from a  platform  into  a vehicle  or  from  one  vehicle to  another,  the  apparatus comprising  a  pair of cranes provided with sets  of  booms, which  comprise  a  base boom (6), a main  boom  (8)  and  a folding  boom (10) and handling unit cylinders (12,  13),  a main  boom  cylinder (12) and a folding boom cylinder  (13), and  support  legs  (20, 21) included in the  apparatus.  At least  one  of  the  cranes is placed on the  chassis  of  a vehicle  (not  shown)  embedded in the  cargo  platform,  so that,  with  the  set  of booms in a  retracted,  i.e.  rest position,  their upper sides are located in the  same  plane as the deck plane of the cargo platform.
Patent NZ-510683-A (NZ)
Title: Sustained release oral formulations of rivastigmine
Inventor: KHANNA SATISH CHANDRA
IPC: A61K9/22
Filed: 1999-10-01
Abstract: A  pharmaceutical composition capable of  releasing  a therapeutically  effective dose of an  active  agent,  e.g., rivastigamine,  in  a time-controlled manner  is  disclosed, wherein  a  first  component  comprising  a  first  dose  of rivastigamine wherein on contact with water  70  to  95%  of said  dose  is  released within 3 to 4 hours, and  a  second component  comprising  a  second dose  of  rivastigamine,  a water  soluble osmosis inducing agent and a water  swellable excipient,  the  second component having a  water  permeable coating which, in use on contact with water, ruptures  after a delay, and releases the active agent.
Patent NZ-514071-A (NZ)
Title: Method and device for packaging carbon dioxide snow in a plastic film
Inventor: GIBOT CLAUDE
IPC: B01D3/14
Filed: 2001-09-10
Abstract: A method and apparatus for packaging carbon dioxide snow in a plastic film container, in which method the following steps are employed: a) a fluid which has a temperature below the dew point of air is injected into and in contact with the plastic film container, b) the carbon dioxide snow is introduced into the plastic film container c) and  the plastic film container is closed.
Patent NZ-514988-A (NZ)
Title: Acoustic flow meters
Inventor: COLE TREVOR
IPC: G01P5/24
Filed: 2000-05-29
Abstract: Acoustic flow meters are used for the measurement of flow velocity of fluids. They have particular application in meters for gas and water in pipelines. The meter includes a tube fitted with three or more acoustic transducers distributed along its length and arranged to transmit wave packets up and down between at least two pairs of the acoustic transducers. The wave packets comprise a signal including zero crossings spaced apart by a packet period determined by a known packet frequency. The flow meter also includes measurement means associated with the transducers to make first measurements of received packets, from which the time of arrival of the zero crossings of a received packet can be determined relative to the time of transmission of the packet. A second measurement from which a particular zero crossing in the transmitted packet can be identified in the received packet. And calculation means to determine the velocity of fluid flow in the tube using the measurements.
Patent NZ-514989-A (NZ)
Title: 6-alkenyl-, 6-alkynyl- and 6-epoxy -epothilone derivatives
Inventor: KLAR ULRICH
IPC: A61K31/429
Filed: 2000-05-01
Abstract: An epothilone compound has the formula I wherein: Rla and Rlb are independently hydrogen, optionally substituted alkyl, aryl, or aralkyl or taken together form a -(CH2)m- or -(CH2)-O-(CH2)-group,; m is 1 to 5; R2a is hydrogen, optionally substituted alkyl, aryl, or aralkyl, or a group of formula (II); R2b is -(CH2)rb-C=C-(CH2)pb-R26b, -(CH2)rb-C=C-(CH2)pb-R26b or a group of formula (III), n is 0 to 5; ra and rb are independently 0 to 4; pa and pb are independently 0 to 3 R3a is hydrogen, optionally substituted alkyl, aryl, or aralkyl; R3b is OH or OPG14; R14 is hydrogen, OR14a or Hal; R4 is hydrogen, optionally substituted alkyl, aryl, or aralkyl, Hal, OR25 or CN; R5 is hydrogen, optionally substituted alkyl, aryl, or aralkyl or (CH2)s-T; s is 1 to 4; R6 and R7 are independently hydrogen, or taken together form an additional bond or an oxygen atom; G is X=CR8- or a bi- or tricyclic aryl; D-E is -CH2-CH2- or -O-CH2-, A-Y is O-C(=O), O-CH2, CH2C(=O), NR29-C(=O) or NR29-SO2; Z is an oxygen atom or H and OR12 and R14a, PG14, R25, R26a, R26b, T, R8, X, R29, R12 are as defined in the specification. The compounds are useful for treating a disease or condition associated with cell growth, division and/or proliferation.
Patent NZ-515090-A (NZ)
Title: Improvements in or relating to object location
Inventor: RICKARD DAVID CHARLES
IPC: G01S5/00
Filed: 2000-05-11
Abstract: A  system  for locating an object (10)  that  produces identifying signals comprises a plurality of receiver  sites (22,  24,  26,  28) arranged in an array (20) for  receiving signals  from  the  object (10) and for receiving  a  common time  reference in the form signals received from  a  global navigation  system   (50)  is  disclosed.   The  array  (20) comprises   a  reference  receiver  site  (22)   and   three auxiliary receiver sites (24, 26, 28) that are connected  to the  reference  site  by  data links  (34,  36,  38).   Each receiver  site  (22, 24, 26, 28) receives signals  (42,  44, 46,  48)  from  the object (10) and timing  control  signals (52,  54,  56,  58)  from a global navigation  system  (50). Each  site determines a time difference between the  receipt of  the object signals and the timing signals, the auxiliary sites  (24,  26, 28) providing data signals  on  data  links (34,  36,  38) to the reference site where the  location  of the object (10) is determined.
Patent NZ-515394-A (NZ)
Title: Staphyloccocus aureus antigen-containing whole cell vaccine
Inventor: FATTOM ALI L
IPC: A61K39/00
Filed: 2000-05-10
Abstract: The application describes a vaccine that comprises (A) cells, cell lysates, or cell derivatives of Staphylococcus aureus which carry an antigen that i) comprises â-linked hexosamine, ii) contains no O-acetyl groups detectable by nuclear magnetic resonance spectroscopy, and iii) specifically binds antibodies to Staphylococcus aureus Type 336 deposited under ATCC 55804, (B) cells, cell lysates or cell derivatives of Staphylococcus aureus which carry Type 5 antigen and/or cells, cell lysates, or cell derivatives of Staphylococcus aureus which carry Type 8 antigen and (C) a pharmaceutically acceptable carrier. A use of the vaccine is described for the preparation of an agent for the treatment of a subject that has or is at risk of developing an S. aureus infection.
Patent NZ-516472-A (NZ)
Title: Anchoring or weighing system for portable road signs and barricades
Inventor: EVANS PETER ERIC
IPC: E01F9/692
Filed: 2000-06-07
Abstract: An anchoring system (1) for portable barricades or barriers, comprising a base (2) having a cavity space therein to contain water, a vertical post or bollard (3) adapted for attachment to the upper end of the base by a bayonet type fit between the base and the lower end of the post (12, 13), and wherein the upper end of the post includes a horizontal extending slot (5) adapted to receive either a single or two overlapping barricade barrier boards. The upper end (7) of the post (3, 4) may incorporate a warning light (6). The base (2) may incorporate a carry handle (15).
Patent NZ-524233-A (NZ)
Title: Method for allowing multi-user orthogonal and non-orthogonal interoperability of code channels
Inventor: PROCTOR JAMES A
IPC: H04W74/02
Filed: 2001-07-06
Abstract: In a system which supports code division multiple access communication among members of a first group of terminals and among a second group of terminals, a method comprises: assigning to the first group of terminals a first code, each user of the first group being unique identifiable by a unique code phase offset; assigning to the second group of terminals the same code as used by the first group but each user of the second group using a common phase offset of that code and assigning to each user of the second group an additional code, the additional code being unique for each of the terminals of the second group. A wireless communication system comprises: a first set of access units and a second set of access units, the first set of access units and the second set of access units capable of communicating with a central base station wherein the first set of access units use a chip rate scrambling code to separate their user channels, each individual unit of the first set of access units having at least one unique, non-orthogonal scrambling sequence that is selected from a unique phase shift of a longer pseudorandom noise sequence, and wherein the second group of access units share a common chip rate scrambling code that is not used by the first group of access units.
Patent NZ-527948-A (NZ)
Title: Aquatic animal treatment method and composition containing pimenta extract
Inventor: YOSHPA MICHAEL
IPC: A61K/
Filed: 2002-02-26
Abstract: A method for treating a diseased or injured aquatic animal, this includes bacterial diseases, fungal diseases or any wounds, lacerations, abrasions or burns, comprises administering a sufficient amount of Pimenta racemosa extract. Pimenta racemosa extract can also promote resistance of disease for disease-free aquatic animals. Also described is a composition comprising an aqueous emulsion of Pimenta racemosa extract oil in water and it may also contain an emulsifier.
Patent NZ-528009-A (NZ)
Title: Enhanced bezel for currency acceptor
Inventor: HAND PETER E
IPC: G07F7/04
Filed: 2002-03-11
Abstract: An enhanced bezel intended for use with a bill acceptor. The enhanced bezel includes a processor to monitor detailed information about the status of the bill acceptor, and other information related to its operation. The processor displays this information through multiple indicators on the enhanced bezel.
Patent NZ-529544-A (NZ)
Title: Encapsulation of nanosuspensions in liposomes and microspheres
Inventor: SOLIS ROSA MARIA
IPC: A61K9/51
Filed: 2002-05-31
Abstract: Disclosed herein a delivery system comprising at least one hydrophobic agent dispersed in aqueous phase as a nanosuspension in at least one chamber bounded by at least one membrane, wherein the delivery system is selected from the group consisting of liposome, multivesicular liposome and microsphere.
Patent NZ-530158-A (NZ)
Title: Irradiation chamber
Inventor: GARA STEPHEN
IPC: A61L2/00
Filed: 2003-12-15
Abstract: An irradiation Chamber Comprising: a rigid first plate having a first surface and a second surface, said second surface having a raised boundary surrounding a plurality of raised partitions; a rigid second plate having a first surface and a second surface, said second surface having a raised boundary surrounding a plurality of raised partitions; wherein the second surface of said rigid first plate is contacted with the second surface of said rigid second plate thereby forming a chamber; said chamber, defined by the raised boundary surrounding the plurality of raised partitions which extend from said second surface of said first plate and said second surface of said second plate, said chamber having a first port and a second port, wherein a plurality of channels are formed by said partitions providing fluid communication with the first port and the second port.