baber/WOPTO huggingface dataset:
Patent YU-57601-A (YU)
Title: Epothilon derivatives, method for the production and the use thereof as pharmaceuticals
Inventor: KLAR ULRICH
IPC: A61K31/422
Filed: 2000-02-11
Abstract: The invention relates to the novel epothilon derivatives of general formula (I) wherein R4 is hydrogen, C1-C10 alkyl, aryl, C7-C20 aralkyl, R5 is hydrogen, C1-C10 alkyl, aryl, C7-C20 aralkyl, R6, R7 are each a hydrogen atom, or together an additional bond or an oxygen atom, R8 is a methyl group or hydrogen, and simultaneously R1a and R1b together represent a trimethylene group and X is a 2-pyridyl, 2-methyl-4-thiazolyl or 2-methyl-4-oxazolyl residue or simultaneously R1a and R1b together represent a trimethylene group, R2 is a methyl, ethyl or propyl group and X is a 2-pyridyl, 2-methyl-4-thiazolyl or 2-methyl-4-oxazolyl residue or simultaneously R1a and R1b each represents a methyl group, R2 is a methyl, ethyl or propyl residue and X is a 2-pyridyl, 2-methyl-4-thiazolyl or 2-methyl-4-oxazolyl residue, wherein the nitrogen and/or sulfur atom in X can be present in oxidized form and, if R2 and R8 each means a methyl residue, X can only be a 2-pyridyl residue which is optionally oxidized at the nitrogen atom, including all possible stereoisomers and their mixtures. The novel compounds are useful for producing medicaments.
Patent RS-77904-A (RS)
Title: Oral administration form for difficulty soluble basic active ingredients which are applied orally
Inventor: BRAUNS ULRICH
IPC: A61K31/4439
Filed: 2003-03-04
Abstract: The invention relates to a novel, oral administration form for active ingredients exhibiting pH-dependent solubility characteristics and the pharmacological compatible salts thereof, which improves the bioavailability of the active ingredient thereof.
Patent AP-942-A (AP)
Title: Process for preparing 2- azadihydroxybicyclo[2.2.1]heptane compounds and the L - tartaric acid salt of the compound.
Inventor: O'BRIEN MICHAEL K
IPC: C07D209/02
Filed: 1997-10-15
Granted: 2001-02-16
Abstract: A method according to the invention is directed to the preparation of a 2-azadihydroxybicyclo [2 .2 .1] heptane compound of formula (I) or (I') wherein * represents an R chirality, *' represents an S chirality, R is hydrogen or, respectively, a group of formula (II) or (II') wherein Rj. is alkyl and Ar is optionally substituted aryl, comprising bishydroxylating a bicyclo[2.2.1]heptane compound of formula (III) or (III') wherein *, *' and R are as previously defined, in the presence of about 0.1 mol % to about 5 mol % of a metal osmate compound or about 0.06 mol % to about 0.07 mol % osmium tetroxide, and an oxidizing agent capable of regenerating osmium tetroxide. The invention is also directed to the treatment of the (1R) diastereomer of the 2-azadihydroxybicyclo [2.2.1] heptane compound (I) wherein R is a group of formula (II) with L-tartaric acid, and the L-tartaric acid salt product thereof. Furthermore, the invention is directed to using the (1R) diastereomer of the 2-azadihydroxybicyclo[2.2.1]heptane compound in an acid facilitated acetalizing or ketalizing reaction that results in the protection of the dihydroxy moieties thereof in isopropanol. In addition, the invention is directed to oxidizing a bis O-protected derivative of the (1R) diastereomer of the 2-azadihydroxybicyclo[2.2.1]heptane compound to a corresponding lactam compound in the presence of about 0.01 mol % to about 1 mol % of Ruo2 with about 3 equivalents of an oxidant to form the lactam compound with an enantiomeric excess ("ee") of greater than or equal to about 95%.
Patent AU-1043088-A (AU)
Title: Solid phase immunoassay
Inventor: KEMENY DAVID MICHAEL
IPC: G01N33/52
Filed: 1987-12-04
Abstract: In a solid phase immunoassay, e.g. RAST or PRIST, the sensitivity can be substantially increased by reducing the volume of liquid in which the indicator (e.g. <125> I anti-IgE) is contained, preferably to the saturation volume of the paper carrier. If the volume of sample is also similarly reduced, the incubation time can be reduced to as little as 5 minutes without loss of sensitivity in comparison with conventional tests. A washing device for the paper carrier is also disclosed, together with immunoassay kits for use in the method of the invention.
Patent AU-1180592-A (AU)
Title: 4-desoxy-4-epipodophyllotoxin derivative or pharmaceutically acceptable salt thereof
Inventor: TERADA TADAFUMI
IPC: A61P35/00
Filed: 1992-01-22
Abstract: A 4-desoxy-4-epipodophyllotoxin derivative represented by general formula (I), a pharmaceutically acceptable salt thereof, and an antitumor drug containing the same as the active ingredient. In formula (I) R and R1 are as defined in the specification. <CHEM>
Patent AU-1303088-A (AU)
Title: Acetylenes disubstituted with a heteroaromatic group and a tetralin group having retinoid like activity
Inventor: CHANDRARATNA ROSHANTHA A S
IPC: A61K31/455
Filed: 1988-03-11
Abstract: Retinoid-like activity is exhibited by compounds of the formula <CHEM> where R is hydrogen or lower alkyl; A is pyridyl, thienyl, furyl, pyridazinyl, pyrimidinyl or pyrazinyl; n is 0-5; and B is H, -COOH or an ester or amide thereof, -CH2OH or an ester or ester derivative thereof, or -CHO or an acetal derivative thereof, or -COR1 or a ketal derivative thereof where R1 is -(CH2)mCH3 where m is 0-4; or a pharmaceutically acceptable salt thereof.
Patent AU-1373792-A (AU)
Title: Toothbrush having a flexibly linked zone in its head
IPC: A46B15/00
Filed: 1992-03-21
Abstract: A toothbrush having a handle and a bristle bearing head made of a plastics material, the head being flexibly and resiliently linked to a frame which wholly or partly surrounds the head, the relative dimensions of the head and the frame being such as to leave a gap between the head and the frame such that the head and frame are capable of relative rocking motion about the gap, the gap being wholly closed with a flexible and resilient elastomeric material.
Patent AU-1497783-A (AU)
Title: Assaying motolity of sperm in semen
Inventor: WOOLHOUSE JAMES KEITH
IPC: G01N21/47
Filed: 1983-05-25
Abstract: A micro-sample of semen is exposed to a beam of light from an inexpensive and small laser device. Light scattered by the sample is detected by a photodetector. The photodetector signal is analyzed in the frequency domain to provide a measure of the amplitude of the signal components having frequencies above about 100 Hz. This measure is representative of the numbers of motile sperm in the sample. A motile/immotile percentage is obtained by dividing the motile measurement by a value representative of the amplitude of the full-frequency photodetector signal. In a preferred embodiment frequency-amplitude analysis is carried out in the time domain using frequency splitting filters and integrating the filtered signals. The light receiving aperture for the photodetector is made annular or part-annular in shape to overcome sample orientation or polarization effects.
Patent AU-1576695-A (AU)
Title: Method of making a UD crossply PWB laminate having one or more inner layers of metal
Inventor: MIDDELMAN ERIK
IPC: B29C70/20
Filed: 1995-01-25
Abstract: The invention relates to a method of manufacturing a composite laminate having a plurality of UD layers, i.e., layers of matrix material reinforced with unidirectionally oriented fibres, and at least one inner metal layer, i.e., a metal layer that does not form an outer surface of the laminate, the layers being arranged so as to give a balanced and symmetric laminate. The method comprises passing through a laminating zone, preferably a double-belt press, unidirectionally oriented (UD) fibres provided with not yet consolidated matrix material and consolidating the matrix material. In a first step a non-flowing sandwich laminate of at least three layers is formed, the at least three layers being UD and metal layers, the sandwich laminate being formed by passing UD fibres provided with not yet consolidated matrix material through the laminating zone together with metal foil, and in a second step the non-flowing sandwich laminate is provided on its outer surfaces with UD layers, with additional UD layers optionally being added in subsequent steps.
Patent AU-1586788-A (AU)
Title: Apparatus for the on-line treatment of degassing and filtration of aluminum and its alloys
Inventor: PIRAS LEONARDO
IPC: C22B21/06
Filed: 1988-05-10
Abstract: Apparatus for on-line degassing and filtering aluminum and its alloys, constituted by a thermally insulated container body, provided with a removable lid (2) incorporating heating means (7) for heating the metal to be processed, said container body being internally subdivided, by means of a vertical partitioning wall (11) into two chambers communicating with each other only in the nearby of the bottom of the container, wherein in one of said two chambers, provided with an inlet for the liquid metal to be processed, injection means (13, 14) are provided, for injecting inert, and/or active gases, which are so located as to perform a degassing in countercurrent relatively to the entering metal stream, whilst at the bottom of the second chamber at least a substantially horizontal plate, or wall (12) is provided, made of a porous material, such as ceramic, graphite, or the like, which is positioned spaced apart from the bottom of the container, such to allow the metal, coming from the first chamber, to flow upwards, and pass through said porous plate, with a rising movement of laminar type.
Patent AU-1618101-A (AU)
Title: An oncolytic adenovirus
Inventor: JOHNSON LEISA
IPC: A61K35/76
Filed: 2000-11-14
Abstract: Viral vectors and methods of making such vectors are described that preferentially kill neoplastic but not normal cells, the preferred vector being an adenovirus that has the endogenous promoters in the E1A and/or E4 regions substituted with a tumor specific promoter which is preferably E2F responsive.
Patent AU-1806197-A (AU)
Title: A process for the preparation of diphosphonate derivatives
Inventor: GRINTER TREVOR JOHN
IPC: C07F9/40
Filed: 1997-02-21
Abstract: PCT No. PCT/GB97/00481 Sec. 371 Date Aug. 20, 1998 Sec. 102(e) Date Aug. 20, 1998 PCT Filed Feb. 21, 1997 PCT Pub. No. WO97/31004 PCT Pub. Date Aug. 28, 1997A process for the preparation of a compound of formula I, wherein R1 and R2 are independently C1-6 alkyl, R3 is hydroxy and R4 and R5 are independently C1-6 alkyl is disclosed. The process comprises reacting a compound of formula II, wherein R1, R2 and R3 are defined as in formula I and X is a leaving group, with a compound of formula III, wherein R4 and R5 are independently C1-6 alkyl, in the presence of a base.
Patent AU-1887988-A (AU)
Title: Monoclonal antibodies against e7 protein of human type 16 papillomavirus, a process for their preparation, and their use
Inventor: OLTERSDORF TILMAN
IPC: C12N15/00
Filed: 1988-07-08
Abstract: Six monoclonal antibodies against E7 protein of human papillomavirus type 16 have been raised and all react with the E7 protein in an ELISA.
Patent AU-1909895-A (AU)
Title: A conversion kit for a machine for automatic intravascular injection of solutions
Inventor: MULLER-SPATH REINHARD
IPC: A61M5/145
Filed: 1995-01-25
Abstract: The conversion kit for an automatic injection system, for the intravasal injection of parenteral solutions such as an X-ray contrast agent, is for high pressure injections and hand injection syringes (12). The max. dia. of the leading end edge (6) of the cylinder grip plate is equal to or smaller than the dia. of the guide holder (19). At least one reduction sleeve (23), to reduce the effective inner dia. of the cylindrical guide holder (19), has a cylindrical sleeve body (24) with an outer dia. matching the inner dia. of the guide holder (19), and an inner dia. matching the outer dia. of the hand syringe body (5). A peripheral edge (26) at the leading end of the reduction sleeve can be held in the opening (17) of the holder body (19) where it projects radially from the sleeve body (24). It has a recess (27) to take the peripheral edge (26) of the reduction sleeve (23) with the aligned peripheral edge (6) of the hand syringe. At least one plunger conversion holder (29) has a radial max. dia. (D) equal to or smaller than the plunger (11) dia. of the hand syringe (12). A mounting (30) gives a release fitting at the free end of the spindle rod (10) and with a coupling head (31) to link the plunger holder (29) to the plunger of a high pressure syringe, and to press on the plunger (11) of the hand syringe (12).
Patent AU-1982695-A (AU)
Title: Process for increasing the molecular weight of polyamides and other condensation polymers
Inventor: ANOLICK COLIN
IPC: C08G69/00
Filed: 1995-03-07
Abstract: This invention concerns a process for increasing the molecular weight and viscosity of polyamides and other condensation polymers, by first injecting an inert gas into the polymer melt at elevated pressure, then stripping the volatiles from the polymer through the application of reduced pressure, followed by holding the polymer at elevated temperatures long enough for the reaction to occur. Activators may be added to the polymer. Port areas used in the stripping zone, may be kept hot for continuous operation.
Patent AU-2030788-A (AU)
Title: Dye for thermal transfer printing
Inventor: GREGORY PETER
IPC: B41M5/385
Filed: 1988-08-02
Abstract: A thermal transfer printing sheet, suitable for use in a thermal transfer printing process, comprising a substrate having a coating comprising a water-insoluble dye of the formula: <CHEM>  wherein  R represents the residue of an active methylene compound; X represents hydrogen, halogen or an optionally substituted alkyl, aryl or heteroaryl radical; Y represents cyano, nitro, alkanoyl, aroyl, alklsulphonyl, arylsulphonyl or a group of the formula -COOR<1> or -CONR<2>R<3> wherein R<1> represents a hydrocarbyl radical and each of R<2> and R<3>, independently, represents hydrogen or a hydrocarbyl radical; and E represents the residue of a coupling component.
Patent AU-2107997-A (AU)
Title: Method for separating cells, especially platelets, and bag assembly therefor
Inventor: UNGER PETER
IPC: A61K35/14
Filed: 1997-02-17
Abstract: Method of separating cells in a centrifuge, preferably for producing platelets. A cell suspension is provided in a processing bag and is centrifuged. The cell enriched fraction is transferred to a storage bag via an outlet tube. The outlet tube is arranged with a portion thereof in a position adjacent the periphery of the centrifuge. When the enriched fraction is transferred through the outlet tube placed at the periphery of the centrifuge and during centrifugation, the outlet tube operates as a cell trap and the enriched fraction is further separated. Preferably, the cell suspension is buffy coat and the enriched fraction comprises platelets. The corresponding bag assembly comprises a processing bag intended to enclose the cell suspension. The processing bag is placed in a centrifuge rotor for separating the cells into a fraction enriched on platelets by centrifugation. An outlet tube transfers the enriched fraction to a storage bag and is placed in a position adjacent the periphery of the centrifuge rotor for further separation of the enriched fraction at transferring, during continued centrifugation, the enriched fraction through the outlet tube.
Patent AU-2263101-A (AU)
Title: Low boron containing microfiberglass filtration media
Inventor: PIERCE MARY E
IPC: D04H1/42
Filed: 2000-12-14
Abstract: The present invention provides nonwoven glass composites formed from an essentially boron free glass wool and an essentially boron free chopped glass fiber, used as a reinforcing material. The nonwoven glass composites are suitable for air filtration apparatus and can be used in the semiconductor industry where the elimination of boron from clean rooms is of importance.
Patent AU-2539197-A (AU)
Title: Polypeptides having phytase activity and nucleic acids encoding same
Inventor: BERKA RANDY M
IPC: A23L5/20
Filed: 1997-03-18
Abstract: The present invention relates to isolated polypeptides having phytase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing the polypeptides. The present invention further relates to composite feeds and methods of reducing phytate levels.
Patent AU-2640684-A (AU)
Title: Production of vinyl chloride - ethylene terpolymese
Inventor: BALL PETER
IPC: C08F291/00
Filed: 1984-04-04
Abstract: A process for the preparation of finely-divided aqueous copolymer dispersions with a solids content of 10 to 70% by weight, based on the dispersion, comprising emulsion polymerizing (a) 1 to 50% by weight of ethylene and (b) 99 to 50% by weight of at least two ethylenically unsaturated comonomers in the presence of a free-radial initiator and at least one member of the group consisting of emulsifier and a protective colloid and optionally present conventional adjuvants, the ethylenically unsaturataed comonomers being (b1) 79.5 to 99.5% by weight of vinyl chloride, (b2) 0 to 15% by weight of ethylenically unsaturated oil-soluble monomers, (b3) 0.5 to 10% by weight of ethylenically unsaturated, functional, water-soluble monomers and (b4) 0 to 5% by weight of oil-soluble monomers monoethylenically unsaturated and containing functional groups or polyethylenically unsaturated and mixtures thereof with the proviso that the monomers of (b2) and (b4) are copolymerizable with (a) and (b1), the comonomers being initially present in 1 to 40% by weight and the content of the water-soluble monomers being 1 to 35% by weight of the comonomers phase initially present and the rest of component (b) being added as an aqueous emulsion during polymerization and the polymerization is effected at 0 DEG  to 120 DEG  C. with an ethylene pressure of 10 to 150 bar which is built up at the latest by the point in time at which polymerization of the initial material is complete.
Patent AU-2860801-A (AU)
Title: Air separation method and plant
Inventor: FUENTES FRANCOIS
IPC: F25J3/04
Filed: 2000-12-28
Abstract: The pressurized waste nitrogen (11) from a column of an air separation unit (10) is sent, optionally after being compressed, to a combustion chamber (15) where it is heated, to a turbine (17) in which it is expanded and again to the combustion chamber (15) where it is mixed with the flue gases in order to give up waste heat thereto.
Patent AU-3055289-A (AU)
Title: Apparatus and method for tracking a rotating blade to determine parameters associated with the rotation of that blade
Inventor: HADLEY MAXWELL RICHARD
IPC: G01S17/74
Filed: 1989-01-13
Abstract: PCT No. PCT/GB89/00035 Sec. 371 Date Sep. 13, 1990 Sec. 102(e) Date Sep. 13, 1990 PCT Filed Jan. 13, 1989 PCT Pub. No. WO89/06623 PCT Pub. Date Jul. 27, 1989.An apparatus for tracking a rotating blade to determine parameters associated with the rotation of that blade. In one embodiment, the apparatus includes a detector in which at least two sensing photodiodes define substantially fan shaped detector planes and are arranged to sense an illuminated point at a known location on the blade passing through these planes. The time taken for the point on the blade to pass between the planes is measured and parameters associated with the rotation of the blade are calculated therefrom. In another embodiment, the detector defines at least two divergent detector fields, and a reactive radiation source responsive to the passage of the blade through the detector fields is provided on the blade. The reactive radiation source is arranged to radiate a signal such as a light signal which is detected by the detector.
Patent AU-3273600-A (AU)
Title: A process for production of paper materials with improved wet strength
Inventor: LUND MARTIN
IPC: D21H17/09
Filed: 2000-03-16
Abstract: The present invention relates to a process for production of paper materials with improved wet strength, comprising: (a) preparing a suspension of unbleached or semi-bleached chemical or semichemical pulp or pulp from recycled fibres; (b) treating the pulp with a phenol oxidizing enzyme and a mediator; and (c) de-watering the treated pulp in a paper making machine to remove process water and produce the paper material. Preferably the paper material is heated after the completion of step (c). Further, the invention relates to a process for producing corrugated paperboard or corrugated containers and to the use of a phenol-oxidizing enzyme in combination with a mediator to produce a paper material with improved wet strength. By the process of the invention the wet strength of paper materials can be improved without using wet strength resins which makes the product more easily re-used.
Patent AU-3346993-A (AU)
Title: Hatch, especially as a closure for flue gas vents in roofs or the like
Inventor: GLASS NORBERT
IPC: F24F13/16
Filed: 1992-12-22
Abstract: The invention relates to a hatch, especially as a cover for flue gas vents in roofs, with an adjustable-height hatch cover, and proposes, in order to obtain a particularly efficient system, that the height adjustment is obtained by the longitudinal movement in oblique slide slots (8, 35) of lifting members (12, 32) on the underside of the hatch cover (6, 7 and 26, 27). The device comprises in particular two hatch covers (6, 7 and 26, 27) which can be moved up and down synchronously and in opposite directions and are allocated to the upper and lower edge of the roof vent (2 and 23) for the purpose of closing.
Patent AU-3385895-A (AU)
Title: Expandable styrene polymers containing recyclate
Inventor: SCHERZER DIETRICH
IPC: C08J9/20
Filed: 1995-08-17
Abstract: PCT No. PCT/EP95/03283 Sec. 371 Date Feb. 27, 1997 Sec. 102(e) Date Feb. 27, 1997 PCT Filed Aug. 17, 1995 PCT Pub. No. WO96/07694 PCT Pub. Date Mar. 14, 1996The present invention relates to expandable styrene polymers containing recycled polystyrene, having a recycled material content of from 10 to 50% by weight, based on the total weight of the polystyrene, to which alkyldi(2-hydroxyethyl)amines have been added during the polymerization.
Patent AU-3396589-A (AU)
Title: Compositions comprising thermally incompatible polymers
Inventor: FEDERICI CARLO
IPC: B29C48/09
Filed: 1989-05-02
Abstract: Process for the preparation of mixtures of thermally incompatible polymers, said process comprising:   a) feeding into a first extruder (1) a thermoplastic polymer possessing relatively low processing temperatures; b) feeding into at least one second extruder (5) at least one thermoplastic polymer possessing relatively high processing temperatures; and c) feeding the molten polymer of the second extruder (5) into the first extruder (1) at a point near its outlet (4). l
Patent AU-3517384-A (AU)
Title: Method and apparatus for lubricating a moving chain
Inventor: JENDICK MANFRED
IPC: B65G45/02
Filed: 1984-11-07
Abstract: In the periodic lubrication of a circulating link chain conducted around chain guide wheels, irrespective of the chain speed a predetermined constant quantity of lubricant is supplied to each lubrication point on the chain in a time which continually changes with the chain speed. The lubricant is supplied by a series of lubricating piston pumps which are operated successively during each lubrication period in synchronism with the speed of the chain. The working stroke of each pump is the same and is effected by the displacement of a member having an inclined surface arranged to be engaged by one or more rotating governing cams carried by a driving shaft which is coupled to a shaft driven by one of the chain wheels. The driving shaft is coupled and uncoupled at the beginning and end of each lubrication period by means which counts the lubrication points of the chain passing a sensor and is thus also dependent on chain speed.