baber/WOPTO huggingface dataset:
Patent MX-2007012659-A (MX)
Title: Hydroxybenzamide derivatives and their use as inhibitors of hsp90.
Inventor: O'BRIEN MICHAEL ALISTAIR
IPC: C07D401/04
Filed: 2006-04-13
Abstract: The invention provides compounds of the formula (I): or salts, tautomers, solvates and N-oxides thereof; wherein R<sup>1</sup> is hydroxy or hydrogen; R<sup>2</sup> is hydroxy; methoxy or hydrogen; provided that at least one of R<sup>1</sup> and R<sup>2</sup> is hydroxy; R<sup>3</sup> is selected from hydrogen; halogen; cyano; optionally substituted C1-5 hydrocarbyl and optionally substituted C1-5hydrocarbyloxy; R4 is selected from hydrogen; a group -(O)n-R<sup>7</sup> where n is 0 or 1 and R<sup>7</sup> is an optionally substituted acyclic C1-5hydrocarbyl group or a monocyclic carbocyclic or heterocyclic group having 3 to 7 ring members; halogen; cyano; hydroxy; amino; and optionally substituted mono- or di-C1-5 hydrocarbyl- amino; or R<sup>3</sup> and R<sup>4</sup> together form a monocyclic carbocyclic or heterocyclic ring of 5 to 7 ring members; and NR<sup>5</sup>R<sup>6</sup> forms an optionally substituted bicyclic heterocyclic group having 8 to 12 ring members of which up to 5 ring members are heteroatoms selected from oxygen, nitrogen and sulphur. The compounds have activity as Hsp90 inhibitors.
Patent MX-2007012662-A (MX)
Title: Use of an epidermal growth factor receptor kinase inhibitor (egfr) in gefitinib resistant patients.
Inventor: ZACHARCHUK CHARLES M
IPC: A61K31/5377
Filed: 2006-04-07
Abstract: This invention discloses method of treating or inhibiting cancer in a human having at least one of an Exon 19 del E746-A750 and/or an Exon 21 point mutation comprising administering to said human gefitinib and/or iressa alone or in combination with other cytotoxic agents or chemotherapeutic agents and an effective amount of EGFR kinase inhibitor.
Patent MX-2007012685-A (MX)
Title: Repressuring system controlled by a pressure relief relay.
Inventor: GONZALEZ JUAN MANUEL BARRON
IPC: E21B43/00
Filed: 2007-10-12
Abstract: The present invention refers to a device for the controlled repressuring of intermittent oil wells including a mechanical pumping rig and mechanical pumping units with a vertical reciprocating-motion rig, useful in wells that present an extraction with a low percentage of useful product due to the presence of congenital water or gas. The purpose of the present invention is to improve the production in intermittent oil wells by controlling and reducing the percentage of congenital water, thus turning pumping in gas wells into a more effective process, and avoiding the problems related to the handle of said elements.
Patent MX-2008009515-A (MX)
Title: Fiber distribution hub with outside accessible grounding terminals.
Inventor: ZABEL JOSHUA A
IPC: G02B6/44
Filed: 2007-02-07
Abstract: The present disclosure relates to a telecommunications distribution hub having a cabinet that defines a primary compartment. The cabinet also includes one or more main doors for accessing the primary compartment. Telecommunications equipment is mounted within the primary compartment. The distribution hub further includes a secondary compartment that can be accessed from an exterior of the cabinet without accessing the primary compartment. A grounding interface is accessible from within the secondary compartment.
Patent MX-2008011338-A (MX)
Title: Fixed codebook searching device and fixed codebook searching method.
Inventor: EHARA HIROYUKI
IPC: G10L19/107
Filed: 2007-03-08
Abstract: A fixed codebook searching device is provided to suppress an increase of an arithmetic operation amount to be minor even if a filter applied to an audio source pulse has a characteristic that cannot be expressed by a lower triangle matrix, and to achieve a quasi-optimum fixed codebook search. The fixed codebook searching device is comprised of an algebraic codebook (101) for generating a pulse audio vector, a convolution arithmetic operation unit (151) for convoluting an impulse response vector that has a value at a negative time with an impulse response of an auditory-sense weighted synthetic filter to generate a second impulse response vector that has a value at a negative time, a matrix generating unit (152) for using the second impulse response vector to generate a Toeplitz type convolution matrix, and a convolution arithmetic operation unit (153) for convoluting the pulse audio source vector generated by the algebraic codebook (101) with the matrix generated by the pulse audio source vector generating unit (152).
Patent MX-2008013624-A (MX)
Title: Elastic laminate and a method for producing an elastic laminate.
Inventor: WAESTLUND-KARLSSON JAN
IPC: A61F13/72
Filed: 2006-05-12
Abstract: The invention concerns a method for producing an elastically stretchable laminate (19) comprising at least three layers (1, 6, 18), the method including the steps of: a) producing a first laminate (8) comprising a first non-elastic fibrous nonwoven web (1) and an elastic film (6); b) activating the first laminate (8) by incremental stretching in at least one direction to render the first laminate (8) elastically stretchable; c) stretching the activated first laminate (8) to 10-200% in at least one direction; and d) laminating the stretched first laminate (8) to a second non-elastic nonwoven web (18). An elastically stretchable laminate produced in accordance with the method is also disclosed.
Patent MX-2008013817-A (MX)
Title: Freezer frost abatement device.
Inventor: POWERS THOMAS H
IPC: F25D21/04
Filed: 2007-04-27
Abstract: A frost resistant freezer includes a freezer chamber, a door, a cooler, and a desiccant. The freezer chamber has a volume. The door provides access to the freezer chamber. The cooler cools air within the freezer chamber from a first temperature within the chamber immediately following closure of the door to a second, quiescent temperature during a cooling period. The desiccant is disposed within the freezer chamber and is selected to absorb moisture from the freezer chamber at a rate sufficient to reduce the relative humidity within the freezer chamber to a value low enough to prevent the formation of frost within the freezer chamber at the quiescent temperature.
Patent MX-2009001210-A (MX)
Title: High performance low noise helicopter blade aerodynamic design.
Inventor: AGNIHOTRI ASHOK K
IPC: B64C27/467
Filed: 2007-08-03
Abstract: One embodiment of the present invention is a main rotor helicopter blade for generating higher lift with less drag and delaying stall at high Mach numbers. A cross-section of this blade includes aft camber. The difference between a chord line of the cross-section and a camber line of the cross-section increases from a leading edge of the cross-section to a maximum between a trailing edge of the cross-section and a midpoint of the chord line and decreases to the trailing edge producing the aft camber of the blade. The aft camber generates higher lift with less drag and delays stall at high Mach numbers.
Patent MX-2009001688-A (MX)
Title: Process for producing biopolymer nanoparticles.
Inventor: BLOEMBERGEN STEVEN
IPC: B29C48/58
Filed: 2007-08-14
Abstract: A process for producing a biopolymer nanoparticles product is disclosed. In this process, biopolymer feedstock and a plasticizer are fed to a feed zone of an extruder having a screw configuration in which the feedstock is process using shear forces in the extruder, and a crosslinking agent is added to the extruder downstream of the feed zone. The biopolymer feedstock and plasticizer are preferably added separately to the feed zone. The screw configuration may include two or more steam seal sections. Shear forces in a first section of the extruder may be greater than shear forces in an adjacent second section of the extruder downstream of the first section. In a post reaction section located after a point in which the crosslinking reaction has been completed, water may be added to improve die performance.
Patent MX-2009003766-A (MX)
Title: Methods of inactivating viruses.
Inventor: LYNCH MICHAEL
IPC: A61K31/201
Filed: 2007-10-09
Abstract: A method of inactivating viruses is provided. The method comprises the step of topically applying an antimicrobial composition comprising: an organic acid; and an anionic surfactant mixture having a characteristic selected from the group consisting of: a linear alkyl chain having a chain length of from about C4 to about C12 and a total head group size of at least about 4 Angstroms; a branched alkyl chain having a chain length of from about C4 to about C12; an unsaturated alkyl chain having a chain length of from about C4 to about C12; and combinations thereof to an area in need of treatment.
Patent MX-2009004427-A (MX)
Title: Method and device for coding transition frames in speech signals.
Inventor: JELINEK MILAN
IPC: G01L19/08
Filed: 2007-10-24
Abstract: There is provided a transition mode device and method for use in a predictive-type sound signal codec for producing a transition mode excitation replacing an adaptive codebook excitation in a transition frame and/or a frame following the transition in the sound signal, comprising an input for receiving a codebook index and a transition mode codebook for generating a set of codevectors independent from past excitation. The transition mode codebook is responsive to the index for generating, in the transition frame and/or frame following the transition, one of the codevectors of the set corresponding to the transition mode excitation. There is also provided an encoding device and method and a decoding device and method using the above described transition mode device and method.
Patent MX-2009005945-A (MX)
Title: Use of pkc inhibitors in transplantation.
Inventor: MAIBUECHER AXEL
IPC: A61P37/06
Filed: 2007-12-05
Abstract: The present invention pertains to the use of a PKC inhibitor in the treatment of insulin-producing cell and tissue rejection, such as islet transplantation rejection or rejection of transdifferentiated insulin-producing hepatocytes.
Patent MX-2009006113-A (MX)
Title: Process.
Inventor: LEARMONTH DAVID ALEXANDER
IPC: C07D311/04
Filed: 2007-12-12
Abstract: A process for preparing the S or R enantiomer of a compound of formula A, the process comprising subjecting a compound of formula B to asymmetric hydrogenation in the presence of a chiral catalyst and a source of hydrogen, wherein: X is CH2, oxygen or sulphur; R-1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkyloxy, hydroxy, nitro, alkylcarbonylamino, alkylamino or dialkylamino group; and R4 is alkyl or aryl, wherein: the term alkyl means hydrocarbon chains, straight or branched, containing from one to six carbon atoms, optionally substituted by aryl, alkoxy, halogen, alkoxycarbonyl or hydroxycarbonyl groups; the term aryl means a phenyl or naphthyl group, optionally substituted by alkyloxy, halogen or nitro group; and the term halogen means fluorine, chlorine, bromine or iodine.
Patent MX-2009007544-A (MX)
Title: Signage apparatus having simple magnet-based structure for ease of modification.
Inventor: PEMBERTON KIRK
IPC: G09F7/04
Filed: 2008-01-11
Abstract: A readily modifiable modular sign apparatus is especially useful for fast food restaurants as backlighted menu boards in both indoor an outdoor applications The apparatus comprises a preferably translucent substrate or mounting board which is preferably planar and has a front surface and a back surface Precisely positioned holes are prepared at selected locations These holes are formed to be aligned with thin metal shims which are affixed on the back surface of the mounting board and receive cylindrical magnets on the front surface The magnets are attached directly to the rear of pÏnted sheets, each of which may have wording or pictorial information or both The magnets contact the metal shims through the mounting board holes, and are held firmly in position by virtue of both the magnetic attractive force and the shape of the walls of the mounting board holes.
Patent MX-2009008176-A (MX)
Title: Heterocyclyl substituted tetrahydronaphthalene derivatives as 5-ht7 receptor ligands.
Inventor: TORRENS-JOVER ANTONIO
IPC: A61K31/00
Filed: 2008-02-06
Abstract: The present invention relates to heterocyclyl-substituted-tetrahydro-naphthalen compounds of general formula (I) and (I prot), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans or animals, mediated by the receptor 5-HT7 affinity.
Patent MX-2009013371-A (MX)
Title: Process for producing exogenous protein in the milk of transgenic mammals.
Inventor: FERNANDEZ NAHUEL
IPC: B01D15/04
Filed: 2008-06-13
Abstract: The invention relates to a non-human transgenic mammal that is useful for the production of a protein of interest that may be toxic to the mammal. The mammal is characterized by the fact that it is transgenic for the production in its milk of an inactive form of the protein of interest, preferably recombinant human insulin. It is not possible to produce recombinant human insulin in transgenic mammals since this molecule has a certain degree of biological activity in the mammals and could be toxic to the mammal. Thus, the invention involves cloning a genetic construct comprising a sequence encoding a modified human insulin precursor under the control of a beta casein promoter in an expression vector. It also involves transfecting the expression plasmid into fetal bovine somatic cells, such as fibroblasts, and enucleating bovine oocytes by nuclear transfer to generate transgenic embryos. The invention gives rise to transgenic bovine that will be able to produce a modified human insulin precursor in their mammary glands. Afterwards, the milk of these transgenic mammals can be collected, the modified human insulin precursor can be converted in vitro into recombinant human insulin, and the recombinant human insulin can be purified to homogeneity as a pure biopharmaceutical product.
Patent MX-2010001038-A (MX)
Title: Personal care article for sequentially dispensing compositions with distinct fragrance characters.
Inventor: SMITH EDWARD DEWEY III
IPC: A61K8/03
Filed: 2008-07-25
Abstract: The present invention relates to a personal care article that comprises a single chamber package and a liquid personal care product. The package comprises a dispensing orifice, a first zone proximate to the dispensing orifice and a second zone distal to the dispensing orifice. The liquid personal care product comprises a first personal care composition substantially disposed within the first zone and the second personal care composition substantially disposed within the second zone. The first composition comprises a first fragrance character and the second composition comprises a second fragrance character; wherein the first fragrance character is distinct from the second fragrance character.
Patent MX-2010001218-A (MX)
Title: Methods and compositions for treating schizophrenia using antipsychotic combination therapy.
Inventor: BACHURIN SERGEY OLEGOVICH
IPC: A01N43/42
Filed: 2008-08-01
Abstract: The present invention relates to combination therapies and methods for treating, preventing and/or delaying the onset and/or development of schizophrenia, wherein the combination therapies comprise a hydrogenated pyrido[4,3 -b]indole or a pharmaceutically acceptable salt thereof, such as dimebon, and an antipsychotic.
Patent MX-2010002357-A (MX)
Title: Improved balloon cuff tracheostomy tube.
Inventor: CUEVAS BRIAN J
IPC: A61M16/04
Filed: 2008-09-15
Abstract: There is provided a balloon cuffed tracheostomy tube (160) with a balloon (175) designed so as to enhance the tube's anchorability without sealing the tracheal stoma (210). The tracheostomy tube device includes a conventional curved hollow tube. The distal (165) end of the tube is adapted for insertion through a tracheal stoma and into the tracheal lumen (200) of a patient's throat. The device further includes an inflatable balloon enveloping a portion of the tube. The balloon has a distal portion (180) substantially centered about and attached to the distal end portion of the tube, and a proximal portion (185) attached to the bend region of the tube and positioned substantially off-center relative to the proximal portion of the tube and about the bend region below the proximal plane of the device. Upon inflation, this configuration provides for expansion of the balloon around the distal end portion of the tube and the proximal end portion of the tube below the proximal plane of the device to seal the trachea below the tracheal stoma and to avoid sealing the trachea above the tracheal stoma. This configuration of the balloon should allow secretions to exit the stoma so that they do not accumulate and become a possible source of ventilator acquired pneumonia.
Patent MX-2010003700-A (MX)
Title: Wireless in-band signaling with in-vehicle systems.
Inventor: BIRMINGHAM KILEY
IPC: H04M3/42
Filed: 2008-10-20
Abstract: This invention pertains to methods and apparatus for data communications from vehicles, to obtain emergencies, concierge and other services, using a voice channel of a digital wireless telecommunications network. Signaling is described (FIG. 3) between a Server and an In?/?hicie System (FIG. 2) for commencing data sessions after establishing a voice channel call. Responsive to a predetermined signaling tone, a switch (PCM) mutes the speaker of the in-vehicie audio system. The call may be initiated from the vehicle automatically, and the call taker location may be unattended. Signaling methods are selected (FIGS. 4-5) for traversing both newer and legacy vocoders for ubiquitous operation.
Patent MX-2010005766-A (MX)
Title: Physical broadcast channel (pbch) transmission for reliable detection of antenna configuration.
Inventor: ZHANG JIANZHONG
IPC: H04L27/18
Filed: 2008-12-02
Abstract: Systems and methods for transmitting data related to the configuration of transmit antennas are disclosed. These methods may include obtaining a data for transmission, encoding the data and modulating the data. During the modulating of the data, the data may be configured in such a way as to convey the configuration of the data through the modulation of the data. These methods may also include obtaining an antenna configuration, obtaining a representation of the antenna configuration, and masking the data with an error correcting code, where the mask corresponds to the antenna configuration.
Patent MX-2010005908-A (MX)
Title: Thuricin cd, an antimicrobial for specifically targeting clostridium difficile.
Inventor: HILL COLIN
IPC: C07K14/32
Filed: 2008-11-28
Abstract: The present invention relates to a new bacteriocin, to microbial strains which can produce it and to uses of the bacteriocin and the strains. The bacteriocin is effective against Clostridium difficile and Listeria monocytogenes amongst other organisms. .
Patent MX-2010010829-A (MX)
Title: Forced lubricating device for the pantograph in pneumatic trains.
Inventor: TORRES JOSE LUIS BINZHA
IPC: B61K3/00
Filed: 2010-10-01
Abstract: Provided are novel and useful improvements in the lubrication of pantographs (positive brush) in pneumatic trains, by means of a forced lubricating device for the pantograph, which basically comprises a forced lubrication cylinder based on a set of holes strategically arranged lengthwise the cylinder, where the axes and the trees include machined grease cavities in each end portion thereof, allowing the arms to be moved, also including bushings designed to support the use and wear, such as sintering bronze bushings.
Patent MX-2010012812-A (MX)
Title: Methods of treatment utilizing binding proteins of the interleukin-21 receptor.
Inventor: O'TOOLE MARGOT
IPC: C07K16/28
Filed: 2009-05-26
Abstract: The present invention provides binding proteins and antigen-binding fragments thereof, including human antibodies, that specifically bind to the human interleukin-21 receptor (IL-21R), and methods of using them. The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing, treating, and/or preventing IL-21R- associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, and other immune system disorders.
Patent MX-2010013268-A (MX)
Title: Implant extraction tool.
Inventor: ANITUA ALDECOA EDUARDO
IPC: A61C8/00
Filed: 2009-06-18
Abstract: The invention relates to an extraction part (1) that can be used to extract an implant (5) screwed to a bone (6) of a patient, including a head (2) for receiving the coupling of a torque-generating system and a threaded body (4), preferably of decreasing diameter, provided with a left-hand thread and intended to be screwed into a hole (7) in the implant (5). The extraction of the implant (5) is relatively simple to perform, said implant (5) being extracted practically clean and leaving a cavity (13) of minimum dimensions in the bone (6) of the patient. As a result, said extraction part (1) enables an implant (5) extraction method that is much less traumatic for the patient.
Patent MX-2010014004-A (MX)
Title: Solid acid catalyst and method for preparing and using the same.
Inventor: CHEN XINMIN
IPC: C07C29/10
Filed: 2010-12-16
Abstract: A solid acid catalyst having a strong acid cation exchange resin having a cross-linking network structure and free aromatic sulfonic acids adsorbed in the network. The solid acid catalyst is prepared by treating a strong acid cation exchange resin with aromatic sulfonic acids in a solution. The catalyst is useful for synthesizing rubber antioxidant RD and other strong-acid catalyzed reactions.
Patent MX-2010014487-A (MX)
Title: Mixture of acetaminophen and oral electrolytes for reconstitution.
Inventor: VELAZQUEZ JACOB CUITLAHUAC ROSALES
IPC: A61K33/00
Filed: 2010-12-21
Abstract: This novel drug, where the paracetamol is dissolved in water and according to the electrolyte ratio, is dissolved in a predetermined water volume, with which three functions are accomplished; a suitable hydration, an analgesic effect for controlling discomforts, an antipyretic effect and as a plus the adherence of the medication. Also has a practical and reliable presentation, so as to be available for all population, providing a better ambulatory management of dengue and avoiding complications thereof.
Patent MX-2011002195-A (MX)
Title: Process and compositions for injections blow molding.
Inventor: KAPUR MIDRULA
IPC: C08K5/00
Filed: 2009-08-28
Abstract: The invention provides a process for injection blow molding an article, said process comprising injecting into a mold cavity a composition, comprising at least one ethylene-based polymer and less than, or equal to, 1000 ppm of a mold release agent, based on the total weight of the composition. The invention also provides a composition comprising a blend, wherein the blend comprises at least one high molecular weight (HMW) ethylene-based polymer, and at least one low molecular weight (LMW) ethylene-based polymer, and wherein the blend has an unsaturation level, as determined by IR, and expressed as vinyls per 1000 carbon atoms, less than, or equal to, 0.5 vinyls per 1000 carbon atoms, and wherein the high molecular weight (HMW) ethylene-based polymer has a density from 0.925 to 0.950 g/cc.
Patent MX-2011004401-A (MX)
Title: Mtor kinase inhibitors for oncology indications and diseases associated with the mtor/p13k/akt pathway.
Inventor: PACKARD GARRICK
IPC: A61P35/00
Filed: 2009-10-27
Abstract: Provided herein are Heteroaryl Compounds having the following structure: R2 N (I) or (II) wherein R1 -R4 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions, comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.