baber/WOPTO huggingface dataset:
Patent CA-2423300-A1 (CA)
Title: Process for the preparation of thiophenols
Inventor: SEIFERT GOTTFRIED
IPC: C07C323/62
Filed: 2001-10-09
Abstract: The invention provides a process for preparation of a thiophenol of formula I   (see formula 1) wherein n is an integer from 1 to 5 and R is hydrogen, alkyl, hydroxyalkyl, alkylamino, dialkylamino, alkenyl, alkynyl, alkoxy, alkylthio, phenyl, naphthyl, phenoxy, phenylthio, halogen, hydroxy, mercapto, carboxyl, sulfo, or heterocyclyl, by reacting a phenyldiazonium salt of formula II  (see formula 2) wherein n and R are as defined for the thiophenol of formula I and X is halogen or hydrogen sulphate, with 1.2 to 5 mol of sulfur powder per mol of the phenyldiazonium salt of formula II, at a temperature in the range of 20 to 100°C, in the presence of 2.5 to 5 mol per mol of the phenyldiazonium salt of formula II of an aqueous base that is an alkali or alkaline earth metal hydroxide or ammonia, converting the excess of sulfur into water soluble thiosulfate by adding of sodium sulfite, sodium hydrogen sulfite or sulfur dioxide, acidifying the reaction solution, and isolating the thiophenol of formula I.
Patent CA-2423949-A1 (CA)
Inventor: VAN KOGELENBERG JACOB
IPC: B65B5/10
Filed: 2003-03-28
Abstract: In a method for inserting piece goods (S) into containers (B) by means of a picking line, the relative speed between the feed of the containers (B) and the feed of the piece goods (S) is controlled in the area of the picking line. In this case, the relative speed is controlled as a function of a filling level of at least one storage element (3, 3', 3'', 4). This method permits efficient transfer of piece goods into containers with the most complete filling possible of the containers, irrespective of the manner of the relative transport direction of the piece goods and containers. It is suitable both for cocurrent and for countercurrent systems,
Patent CA-2424926-A1 (CA)
Inventor: HERR DIETER
IPC: A61K31/155
Filed: 2001-09-27
Abstract: The invention relates to novel amidines and quanidines, the production and u se thereof and the use thereof as trypsine-type serine protease competitive inhibitors, especially thrombine and compliment proteases Cls and Clr. The invention also relates to pharmaceutical compositions which contain said compounds as active ingredients, in addition to the use of the compounds as thrombine inhibitors, anticoagulants, compliment inhibitors and anti- inflammatory agents. The novel compositions are characterised by the linkage  of a serine protease inhibitor having amidine or quanidine functions with an  alkyl radical having two or more hydroxyl functions, whereby said alkyl radical is derived from sugar derivates.Several sugar structural components or components derived from sugar can therefore be linked to each other. Said principle of linking sugar derivates enables oral active compounds to be obtained.
Patent CA-2426377-A1 (CA)
Title: Scaleable multiple-path wormhole interconnect
Inventor: HESSE JOHN
IPC: H04L12/721
Filed: 2001-10-19
Abstract: A family of interconnect structures and switches exploit the interconnect structures to attain scalability, low latency, and single-chip implementations. The disclosed interconnect structures and switches support a wide variety of applications including supercomputer interconnects, LAN switches, IP and ATM switches, telephony central office switching, video on demand servers, interconnects for mainframe database servers, high-speed workstation interconnects, and many others that are known to those having ordinary skill in the art.
Patent CA-2427411-A1 (CA)
Title: Objective lens and optical pickup apparatus
Inventor: HONDA KOJI
IPC: G11B7/1374
Filed: 2001-11-09
Abstract: In an objective lens for use in an optical pickup device, when NA1 and N2 (NA2 < NA1) represent a needed numerical aperture of the objective lens on an image side, a first spot and a second spot represent a spot formed by the light flux having passed through the central region, a mth order diffracted ray and a nth diffracted ray represent a diffracted ray having the maximum diffraction efficiency among diffracted rays, the central region nearly corresponds to a region through which the light flux in the inside of the numerical aperture NA2 passes, the light amount of the nth order diffracted ray which reaches the inside of the second spot is less than that of the mth order diffracted ray which reaches the inside of the first spot, and the mth order diffracted ray and the nth order diffracted ray satisfy the relationship of m = n.
Patent CA-2428425-A1 (CA)
Title: Method of treating hematologic tumors and cancers
Inventor: PARDEE ARTHUR B
IPC: A61K31/00
Filed: 2001-11-07
Abstract: Multiple myeloma and other hematologic tumors and/or malignancies can be treated by administration of a G1 and/or S phase drug, which is preferably .beta.-lapachone, or a derivative or analog thereof, combined with a G2/M  phase drug such as taxane derivative, which is advantageously paclitaxel. This combination of the G1 and/or S phase drug with the G2/M phase drug results in an unexpectedly greater than additive (i.e., synergistic) apoptosis in multiple myeloma cells. The invention includes methods of treating multiple myeloma by administering the combination of the G1 and/or S phase drug and the G2/M phase drug, pharmaceutical compositions comprising the combination of drugs used in these methods, as well as pharmaceutical kits.
Patent CA-2428443-A1 (CA)
Title: Peptides and mixtures thereof for detecting antibodies to severe acute respiratory syndrome-associated coronavirus
Inventor: HOUDE MICHEL
IPC: C07K14/165
Filed: 2003-05-09
Abstract: This invention relates to novel peptides and mixtures thereof useful for detecting SARS-CoV infections. These peptides are also useful as active ingredients in vaccines against SARS-CoV infection.
Patent CA-2433087-A1 (CA)
Inventor: ORGAN LESLIE W
IPC: A61B5/296
Filed: 2001-12-14
Abstract: Publié sans précis
Patent CA-2435027-A1 (CA)
Inventor: LUM MATTHEW K
IPC: B29C53/00
Filed: 2003-07-11
Abstract: There are provided apparatuses and related methods for preforming sheets to form preforms for forming ducts. The preforms can be formed of a thermoplastic material, such as flat sheets of reinforced thermoplastic, which can be lightweight, strong, and perform well in flammability, smoke, and toxicity tests. The apparatus includes a heater for heating the sheet to a processing temperature and a structure for configuring the sheet to a desired shape of the duct. For example, rollers, rods, tubes, or a funnel can be used to bend the sheet.
Patent CA-2436450-A1 (CA)
Inventor: NORRIS ROBERT M
IPC: E21B34/00
Filed: 2003-07-31
Abstract: A remote operated tool string deployment apparatus (RODA) is provided for use with a remote operation coil connector (ROCC) in a well intervention system. The ROCC enables the remote connection of intervention tool strings or bottom hole assemblies (BHA) to the coiled tubing where manually changing them is not possible.
Patent CA-2436597-A1 (CA)
Title: Polycarbonate compositions
Inventor: WITTMANN DIETER
IPC: C08K3/016
Filed: 2001-11-26
Abstract: The invention relates to an impact-resistant modified polycarbonate composition containing a graft polymer and flame proofing agents. The ratio Z of the rubber-containing part Ba which is contained within the graft polymer (B), to the rubber-free part K of vinyl (co)polymer, is higher than 1 in the polycarbonate composition.
Patent CA-2438310-A1 (CA)
Inventor: SLETTEDAL PER
IPC: E21B19/14
Filed: 2002-03-15
Abstract: A gripping apparatus (1) for tubular goods is disclosed. The apparatus comprises two in respect of each other pivotable jaws (1a, 1b) and a working cylinder (8) that effects motion of the jaws (1a, 1b) in respect of a stationary housing (2). A counter block (7) is arranged between the jaws (1a , 1b) in the housing (2), and each jaw is by forced motion movably arranged in respect of the counter block (7). The moveable forced motion causes axial forth and back displacement simultaneous with the opening/closing of the jaw s (1a, 1b). The working cylinder (8) is connected to each jaw (1a, 1b) via respective articulated connection forming pivot axis for the pivotable jaws.
Patent CA-2441810-A1 (CA)
Inventor: HENLEY CHRISTOPHER M
IPC: G06Q40/00
Filed: 2001-03-21
Abstract: Published without an Abstract
Patent CA-2442847-A1 (CA)
Inventor: BEASLEY ELLEN M
IPC: A61K38/00
Filed: 2002-03-28
Abstract: La présente invention concerne des séquences d'acides aminés de peptides qui sont codés par des gènes appartenant au génome humain, en l'occurrence, les peptides d'enzymes de la présente invention. L'invention concerne plus particulièrement des molécules isolées de peptides et d'acides nucléiques, des procédés d'identification d'orthologues et de paralogues des peptides d'enzymes, et des procédés d'identification de modulateurs des peptides d'enzymes.
Patent CA-2444915-A1 (CA)
Inventor: DO SUNG
IPC: B42F7/02
Filed: 2003-10-09
Abstract: A sleeve for holding papers or other material may be provided with an outer corner tab. The sleeve may be formed of a single die-cut sheet of plastic or other material, or from two or more sheets that are attached together. A first sheet may include score fines along two adjacent edges that enable an extended portion of the first sheet to be folded over a second sheet. The second sheet may include score lines that enable an outer corner tab to be formed thereon. The corner tab enables a portion of the papers or other material stored in the sleeve to be inserted into an insert space of the tab. The tab may then be used to retain papers in a secure manner, such that they will not fall out of the sleeve should the sleeve or folder be inverted.
Patent CA-2445731-A1 (CA)
Title: Procede et acides nucleiques pour la differenciation des tumeurs de la prostate
Inventor: MODEL FABIAN
IPC: C12Q1/68
Filed: 2002-06-14
Abstract: La présente invention concerne des séquences génomiques chimiquement modifiées, des oligonucléotides ou des oligomères de la protéine PNA permettant la détection de l'état de méthylation de la cytosine de l'ADN génomique, ainsi qu'un procédé permettant la détermination de paramètres génétiques et/ou épigénétiques de gènes utiles dans la caractérisation, la classification, la différenciation, le diagnostic et le traitement des lésions prostatiques
Patent CA-2446971-A1 (CA)
Title: Use of 3-position cyclosporin derivatives for hair growth
Inventor: KIM SANG-NYUN
IPC: C07K7/64
Filed: 2002-05-11
Abstract: The present invention discloses a hair growth promoting agent comprising a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent comprising a cyclosporin A derivative substituted in the 3-position as an active ingredient.
Patent CA-2450020-A1 (CA)
Inventor: OTTE ARIE PIETER
IPC: A61K48/00
Filed: 2002-06-14
Abstract: The invention is concerned with the systematic elucidation and identification of regulatory sequences. The invention provides among others screenings and detection methods with which regulatory sequences can be identified. The invention further provides regulatory sequences and use thereof in various fields such as, but not limited to protein production, diagnostics, transgenic plants and animals, and the therapeutic field.
Patent CA-2450254-A1 (CA)
Inventor: SEGUIN RICHARD
IPC: E01F9/669
Filed: 2003-11-19
Abstract: Dispositif de signalisation routière pour fournir des informations aux conducteurs qui approchent. Le dispositif de signalisation comprend un élément mobile pouvant être fixé à un support et à un système d'entraînement à énergie solaire. L'élément mobile peut alterner entre une première position et une seconde position, dans laquelle le dispositif de signalisation routière est en marche et fournit de l'information aux conducteurs qui approchent. Le système d'entraînement à énergie solaire est conçu pour permettre à l'élément mobile d'adopter une première position et une seconde position.
Patent CA-2450704-A1 (CA)
Title: Systeme, procede et programme d'analyse d'homologies, et systeme pour etablir la transaction
Inventor: KANAYA SHIGEHIKO
IPC: G16B30/10
Filed: 2001-11-22
Abstract: L'invention concerne un moyen d'analyse BLAST grâce auquel des homologies observées parmi les données contenues dans le groupe de données à analyser et les données contenues dans le premier groupe de données sont respectivement calculées, et le nombre de données homologues (nombre de gènes orthologues) est calculée en tant que première homologie x au moyen des résultats du calcul. En définissant n¿A? seuils E's, la première homologie x¿1? est calculée pour chaque seuil E¿1?. Les homologies observées parmi les données contenues dans le groupe de données à analyser et les données contenues dans le second groupe de données sont ensuite calculées respectivement, et le nombre de données homologues (nombre de gènes orthologues) est calculée en tant que seconde homologie y au moyen des résultats du calcul. En définissant n¿B? seuils E's, la seconde homologie y¿1? est calculée pour chaque seuil E¿1?. Un moyen d'étalonnage T est utilisé pour déterminer que les groupes de données à analyser sont analogues soit au premier groupe de données soit au second groupe de données, sur la base de la relation entre la première homologie x¿1?, la seconde homologie y¿1? et le nombre de seuils n.
Patent CA-2452468-A1 (CA)
Title: Ball indenter utilizing fea solutions for property evaluation
Inventor: LEE HYUNG-YIL
IPC: G01N3/06
Filed: 2002-07-18
Abstract: An automated indentation system based on finite element solutions or performing a non-destructive compression test by loading a compressive indentation load (P) and calculating a elastic modulus (E) and a yield strength (so), and a hardening exponent (n) from measured indentation depth (ht) and indentation load (P), and unloading slope (S). The system comprises a stepmotor control system (1), a measurement instrumentation (2) having a load cell (15), laser displacement sensor (17) for measuring the indentation depth and ball indenter (18), a data acquisition system (3) having an signal amplifier for amplifying and filtering signals from the load cell (15) and laser displacement sensor (17), and a control box (4) pre-stored computer programming algorisms for adjusting and controlling the moving speed and direction of stepmotor (12). The control box (4) enables storing and retrieving the signals of measured data and material properties, and plotting the graphs of load-depth curve and stress-strain curves based on the signal data. The procedure of computer programming algorithm is as follows: First, the Young's modulus E is computed from Eq. (29) by using slope S and initially guessed values of n and eo. Then, c2, ep and s are calculated as many as the number of load and depth data. From these, the values of n, K, so and eo are calculated from stress-strain relation. And then updated E, d, c2, ep, s, n, K, so and eo are repeatedly calculated until the updated eo and n are converged within the tolerance.
Patent CA-2453973-A1 (CA)
Title: On-demand creation of posix locale source
Inventor: ROSE DANIEL A
IPC: G06Q40/00
Filed: 2003-12-23
Abstract: A method for creating a specific POSIX style locale source file, on demand, suitable for compilation in a computer is provided the method comprising, receiving a request submitted for the specific POSIX style local e, and obtaining a plurality of localization values related to the specific POSIX style locale. Next, determining a category within the plurality of localization values and selecting process routines dependent upon the category, and then selectively extracting the category information. After extracting the category informati on is stored into a memory of the computer. A determination is made regarding more categories to process, which might result in processing the remaining categories, otherwise assembling the extracted information into the POSIX style locale source file. Assembling may entail addition of no files ar files such as LC- CTYPE and LC_COLLATE to form a locale source suitable for compilation
Patent CA-2454427-A1 (CA)
Inventor: SANDRASAGRA ANTHONY
IPC: C12N1/19
Filed: 2002-07-19
Abstract: Novel GAVE8 polypeptides, proteins, and nucleic acid molecules are disclosed . In addition to isolated, full-length GAVE8 proteins, isolated GAVE8 fusion proteins, antigenic peptides and anti-GAVE8 are provided.The invention also provides GAVE8 nucleic acid molecules, recombinant expression vectors containing the nucleic acid molecule, host cells into which the expression vectors have been introduced and nonhuman transgenic animals in which GAVE8 gene has been introduced or disrupted are described. Diagnostic, screening, and therapeutic methods utilizing GAVE8 compositions or molecules binding GAVE8 also are provided. Methods for identifying GAVE8 agonists, antagonists , inverse agonists and the like are described.
Patent CA-2454699-A1 (CA)
Title: Method for treating primary insomnia
Inventor: ZISAPEL NAVA
IPC: A61P25/20
Filed: 2002-08-12
Abstract: The invention relates to a medicament, for treating and improving the restorative quality of sleep, in a patient suffering from primary insomnia, which comprises at least one compound selected from melatonin, other melatonergic agents, melatonin agonists and melatonin antagonists, in an effective amount within the range of 0.0025 to 50 mg, and optionally one or more other therapeutically active agents.
Patent CA-2455669-A1 (CA)
Inventor: MARFURT KAREN L
IPC: A61B5/00
Filed: 2004-01-22
Abstract: A reagent strip for measuring the concentration of glucose in whole blood has a polymer on at least one side thereof to increase the opacity thereof; thereby reducing the effect of hematocrit on the glucose determination.
Patent CA-2456077-A1 (CA)
Title: Individualized anti-cancer antibodies
Inventor: TAKAHASHI MIYOKO
IPC: A61K47/48
Filed: 2000-11-08
Abstract: The present invention relates to a method for producing patient specific ant i- cancer antibodies using a novel paradigm of screening. By segregating the an ti- cancer antibodies using cancer cell sytotoxicity as an end point, the proces s makes possible the production of anti-cancer antibodies customized for the individual patient that can be used for therapeutic and diagnostic purposes. The invention further relates to the process by which the antibodies are mad e and to their methods of use. The antibodies can be made specifically for one tumor derived from a particular patient and are selected on the basis of the ir cancer cell cytotoxicity and simultaneous lack of toxicity for non-cancerous cells. The antibodies can be used in aid of staging and diagnosis of a cance r, and can be used to treat tumor metastases. The anti-cancer antibodies can be conjugated to red blood cells obtained from that patient and re-infused for treatment of metastases based upon the recognition that metastatic cancers a re usually well vascularized and the delivery of anti-cancer antibodies by red blood cells can have the effect of concentrating the antibodies at the site of the tumor.
Patent CA-2456647-A1 (CA)
Inventor: CHAN DAVID Y
IPC: H02H3/33
Filed: 2004-02-02
Abstract: A resettable circuit interrupting device such as a GFCI that, when reverse wired during installation, will trip and prevent power being applied to the load side of the GFCI when powered up. A current limiting circuit is connected between the phase and a ground terminal on the line side of the differential transformer of the GFCI. When the GFCI is connected correctly, the current through the current limiting circuit will have no significant effect on the GFCI, and it will operate normally. When, however, the line conductors are connected to the load terminals of the GFCI and the load conductors are connected to the line terminals of the GFCI, the current through the current limiting circuit will appear as a ground fault and cause the GFCI to trip.
Patent CA-2457233-A1 (CA)
Inventor: CESCOLINI DAVID
IPC: B65D35/28
Filed: 2004-02-06
Abstract: A dispenser apparatus for use to dispense a material from a squeezable and collapsible tube is provided. The dispenser apparatus comprises a housing unit having a storage portion at the top end, a dispensing portion at the bottom end, and at least one channel which extends vertically from the top end to the bottom end. The dispenser also includes a feeder plate which is downwardly sloping from the storage portion to the dispensing portion, and a dispensing member above the feeder plate. When the dispensing member is in an open position, passage of one tube from the storage portion to the dispensing portion is permitted, and when the dispensing member is in a closed portion, passage of any tube into the dispensing portion is precluded. When in the dispensing portion, material can be dispensed from the tube, and thus converted the full tube to a collapsed, empty shape. Only when the tube has taken on the collapsed empty shape, is the tube removable from the dispensing portion. A device for reducing theft or other loss of the incompletely used tubes results.
Patent CA-2457330-A1 (CA)
Inventor: SUNDQVIST TOMMY EUGEN
IPC: C07K16/06
Filed: 2002-08-05
Abstract: L'invention concerne un procédé de traitement de maladie inflammatoire intestinale chez un sujet consistant à lui administrer par voie orale une quantité efficace d'une préparation d'immunoglobine polyclonale humaine de mélange. Le procédé permet le traitement d'inflammation de muqueuse à partir du côté de la membrane luminale de la muqueuse gastro-intestinale. Des préparations d'immunoglobine humaine, destinées à être utilisées dans les procédés de l'invention, peuvent être préparées au moyen d'une quelconque des méthodes connues utilisées dans la préparation d'immunoglobine à destination intraveineuse et intramusculaire (parentérale). Il est aussi possible d'obtenir des préparation commerciales d'immunoglobine. La préparation d'immunoglobine humaine peut contenir une classe quelconque des classes connues d'immunoglobines, notamment IgA, IgG, IgM, IgE, et IgD. La préparation d'immunoglobine humaine contient, de préférence, au moins l'une des deux immunoglobines G (IgG) ou A (IgA) ou un mélange d'immunoglobine G (IgG) et d'immunoglobuline A (IgA).
Patent CA-2459579-A1 (CA)
Title: Method of producing silicon metal particulates of reduced average size
Inventor: CARBERRY JOHN
IPC: C01B33/02
Filed: 2002-07-25
Abstract: A method and apparatus of reducing the average particle size of silicon meta l particulates employing a liquid oxidant extractant admixed with the silicon metal particulates while the silicon metal particulates are subjected to attrition in an attrition mill. An essentially oxidant-free silicon metal particulate product is produced, with the particulate product having an average particle size within that range of average particle sizes where the silicon metal particulates are susceptible to violent exothermic reaction wi th an oxidant.
Patent CA-2459749-A1 (CA)
Title: Corps moule a partir de particules noyau-envelopppe
Inventor: RUHL TILMANN
IPC: C08F265/04
Filed: 2002-08-21
Abstract: L'invention concerne des corps moulés à effet optique. Ces corps moulés sont principalement constitués de particules noyau-enveloppe dont l'enveloppe constitue une matrice et dont le noyau est essentiellement solide et a une répartition dimensionnelle des granules sensiblement mono-dispersée. Le matériau noyau et le matériau enveloppe ont des indices de réfraction différents. Les corps moulés sont caractérisés en ce qu'ils sont obtenus par un procédé selon lequel les particules noyau-enveloppe sont chauffées à une température à laquelle l'enveloppe est coulante puis les particules noyau-enveloppe coulantes sont soumises à l'action d'une force mécanique.
Patent CA-2460731-A1 (CA)
Title: Method for the production of oily suspensions of water-soluble enzymes
Inventor: RUNGE FRANK
IPC: A23K40/30
Filed: 2002-09-14
Abstract: The invention relates to oily suspensions of at least one water-soluble enzyme and to a method for the production of said suspensions and the use thereof as additives for animal feed.