baber/WOPTO huggingface dataset:
Patent CA-3028752-A1 (CA)
Inventor: SMITH ALEXANDER
IPC: C07D487/14
Filed: 2017-06-29
Abstract: Cette invention se rapporte au domaine de la synthèse de composés à base de pyrimidine utiles dans le traitement de troubles impliquant une prolifération cellulaire anormale, y compris, mais sans s'y limiter, les tumeurs et les cancers.
Patent CA-3032527-A1 (CA)
Inventor: CHEN CHIN-CHU
IPC: A61P27/02
Filed: 2019-02-04
Abstract: The present invention provides a use of Cordyceps cicadae mycelium active substances, which can be used to manufacture a composition for preventing, postponing or treating ocular diseases, including changes in the anterior/posterior chamber volume, vitreous humour, and/or retinal detachment. A method for preparing Cordyceps cicadae mycelium active substances comprises following steps: (a) culturing a Cordyceps cicadae mycelium on a plate medium between 15-35°C for 5-14 days; (b) inoculating the Cordyceps cicadae mycelium of step (a) into a flask and culturing the mycelium between 15-35°C and pH 2-8 for 3-7 days; and (c) inoculating the Cordyceps cicadae mycelium of step (b) into a fermenter tank and culturing the mycelium by stirring between 15-35°C and pH 2-8 for 3-5 days, so as to obtain a Cordyceps cicadae mycelium fermentation liquid containing the Cordyceps cicadae mycelium active substances.
Patent CA-3034779-A1 (CA)
Inventor: ZHANG CHENG
IPC: G06F3/041
Filed: 2017-08-29
Abstract: A portable electronic device having improved user input capabilities and methods for controlling the same are provided. The device includes sensors capable of detecting and classifying user inputs provided as gestures performed on a surface of the device, wherein the surface does not include the sensors for detection of the gesture, nor is the surface in direct communication with the sensors for detection of the gesture. The device includes a microprocessor that performs instructions in response to the provided user input gestures.
Patent CA-3035104-A1 (CA)
Inventor: CERULLO VINCENZO
IPC: A61K39/00
Filed: 2017-09-06
Abstract: The invention concerns a modified enveloped virus wherein said virus has at least one anti- tumor, tumor-specific peptide non-genetically attached to or inserted in/through the viral envelope; a pharmaceutical composition comprising same; and a method of treating cancer using same.
Patent CA-3036234-A1 (CA)
Inventor: ARMSTRONG CHARLES L
IPC: C12N15/82
Filed: 2017-09-13
Abstract: Methods and compositions for improved plant breeding using gene editing and haploid induction are provided.
Patent CA-3039068-A1 (CA)
Inventor: JASCHINSKI FRANK
IPC: C07H21/00
Filed: 2017-10-09
Abstract: The present invention refers to immunosuppression-reverting oligonucleotides comprising 12 to 18 nucleotides, wherein at least one of the nucleotides is modified, and the oligonucleotide hybridizes with a nucleic acid sequence of an ectonucleotidase (NTPdase; CD73) of SEQ ID NO.1 (human), wherein the oligonucleotide inhibits at least 50 % of the CD39 expression. The invention is further directed to a pharmaceutical composition comprising such oligonucleotide.
Patent CA-3039644-A1 (CA)
Title: Curved magnetic actuators, and systems, and methods for mounting tilt platforms
Inventor: BALABAN SCOTT
IPC: H01F7/08
Filed: 2017-08-11
Abstract: A magnetic actuator, comprising a first magnet having a first magnetic axis and a first magnetic field, a second magnet having a second magnetic axis and a second magnetic field, the magnets defining, at least in part, a magnetic assembly; and a coil actuator assembly at least partially disposed about the magnetic assembly, wherein the first and second magnetic fields collectively approximate a curve. A tilt platform assembly, comprising a support base; a tilt platform pivotally coupled to the support base; at least one coil actuator assembly, mounted to the support base or the tilt platform; and at least one magnet assembly mounted to the other of the support base or tilt platform, and being disposable within the at least one coil actuator assembly, the at least one magnetic assembly comprising at least two magnets having respective magnetic fields angularly offset from one another and that collectively approximate a curve.
Patent CA-3040145-A1 (CA)
Title: Method and systems for the indexing of bioinformatics data
Inventor: BALUCH MOHAMED KHOSO
IPC: G16B45/00
Filed: 2017-07-11
Abstract: Method and apparatus for the indexing of genome sequence data produced by genome sequencing machines. The proposed method can be applied both to raw sequence data produced by sequencing machines and to those sequence reads that cannot be mapped on any reference sequence according to specific matching criteria. This invention describes a method to partition and index unaligned sequence reads to enable browsing and efficient selective access.
Patent CA-3040479-A1 (CA)
Inventor: ORONSKY BRYAN T
IPC: C07D295/06
Filed: 2017-10-13
Abstract: The invention provides sulfoxyalkyl organonitro and related compounds, compositions containing such compounds, and methods for using such compounds and compositions to treat medical disorders, such as a neurodegenerative disorder, autoimmune disease, infection, or cancer in a patient. Exemplary sulfoxyalkyl organonitro compounds described herein include ((2-(3,3-dinitroazetidin-l-yl)-2-oxoethyl)sulfinyl)-D-alanine and variants thereof.
Patent CA-3040540-A1 (CA)
Title: Methodes de traitement et d'inhibition d'une infection par le virus ebola
Inventor: SMITH HAROLD C
IPC: A61K31/519
Filed: 2017-11-06
Abstract: L'invention concerne des méthodes de traitement d'un virus Ebola et d'inhibition de la transmission et de la propagation de celui-ci.
Patent CA-3044758-A1 (CA)
Title: Machine and method for labeling containers
Inventor: SCHINELLI NICOLA
IPC: B65C9/18
Filed: 2017-12-14
Abstract: A machine and a method for labeling containers, the machine comprising a transfer drum (2), fed by an assembly (3) for unwinding a labeling ribbon (4) and provided with cutting means (5), which is adapted to bring the individual labels (17a, 17b), separated after cutting, into contact with corresponding containers (10, 10a, 10b) which are supported by a conveyor (11); a roller (12) for spreading adhesive faces the transfer drum (2) and is designed to apply, to the labels (17a, 17b) that are present on the ribbon (4), at least one line of adhesive (13) prior to their separation from the ribbon (4).
Patent CA-3048617-A1 (CA)
Inventor: BILLER WILLIAM T
IPC: A61M1/36
Filed: 2017-01-16
Abstract: A venous drainage cannula, catheter, or other device is in certain embodiments convertible or adjustable for application in cardiac surgery procedures involving cardiopulmonary bypass. Such a convertible cannula device can be modified, for example, for use as both a multi-stage cannula and a bi-caval cannula, so that the same device can be used in multiple different procedures where one or the other cannula type is needed. Such convertible cannula or other device can simplify and reduce a number of parts needed for a bypass procedure, by providing one adjustable and versatile device to serve multiple functions where different cannulae are traditionally required. Various embodiments further provide cannula devices where a variety of different hole or opening arrangements and configurations can be achieved, to adapt to various different procedures.
Patent CA-3048996-A1 (CA)
Title: Human t cell derived from t cell-derived induced pluripotent stem cell and methods of making and using
Inventor: BLAZAR BRYCE R
IPC: C12N5/0783
Filed: 2016-12-08
Abstract: Induced pluripotent stem cells (iPSCs) derived from a T cell of a T cell subset. T cells derived from iPSCs derived from a T cell. Methods of deriving iPSCs from a T cell. Methods of deriving T cells from iPSCs including deriving a T cell of a T cell subset from an iPSC. Methods of engineering chimeric antigen receptor (CAR)-expressing or T cell receptor (TCR)-expressing iPSC. Methods of administering T cells derived using the methods disclosed. Induced pluripotent stem cell lines derived from T cells, methods of deriving induced pluripotent stem cell lines, and methods of deriving T cells from induced pluripotent stem cell lines.
Patent CA-3052652-A1 (CA)
Title: Anti-pd-l1 antibody treatment of bladder cancer
Inventor: KURLAND JOHN
IPC: C07K16/28
Filed: 2018-02-16
Abstract: Provided are methods of treating bladder cancer (e.g., urothelial carcinoma, UC) in a subject having bladder cancer, e.g., UC, with an effective dose regimen of an anti-PD-L1 antibody, e.g., durvalumab, or an antigen binding fragment thereof. Also provided are methods in which an anti-PD-L1 antibody is used in combination with another immunotherapeutic agent, e.g., tremelimumab to treat a bladder cancer, e.g., UC, in a subject having bladder cancer. In some cases, the subject undergoing treatment is identified as having a bladder cancer or tumor that is PD-L1-low/neg, or PD-L1-high. Methods are also provided in which anti-PD-L1 antibody treatment of bladder cancer is used following a standard of care or first-line therapy in subjects who have progressed following such therapies or who have relapsed after a prior treatment regimen.
Patent CA-3052760-A1 (CA)
Inventor: CLARKE ELIZABETH JANE
IPC: C12N9/04
Filed: 2018-02-17
Abstract: Provided are engineered organisms which can convert methane or methanol to 3-hydroxypropionate.
Patent CA-3056992-A1 (CA)
Inventor: BOYER SCOTT
IPC: A61K9/70
Filed: 2018-06-08
Abstract: La présente invention concerne un film comprenant un sel d'alginate d'un cation monovalent ou un mélange de sels d'alginate contenant au moins un sel d'alginate d'un cation monovalent, et un antagoniste d'un récepteur aux opioïdes, un agoniste inverse d'un récepteur aux opioïdes, ou un promédicament de ces derniers. La présente invention concerne en outre des procédés de fabrication d'un tel film, et l'utilisation d'un tel film dans le traitement d'un patient humain, en particulier l'utilisation d'un tel film dans le traitement des effets d'une surdose aux opioïdes aiguë, ou l'utilisation d'un tel film pour réduire le risque d'abus d'opioïdes.
Patent CA-3061635-A1 (CA)
Inventor: SCHWEITZER JORDAN
IPC: A45D29/00
Filed: 2019-11-13
Abstract: System, devices, and methods for correcting ingrown nails are disclosed. A  system includes a first anchor and a second anchor configured to be coupled to opposing sides of an ingrown nail of an end user. A first brace and a second brace are configured to be removably coupled to respective ones of the first and second anchors. An elastic loop is secured between the protrusions of the braces to apply continuous tension to the braces. The tension is distributed to the nail through the anchors to which the braces are coupled. The amount of tension applied to the nail can be selected by selecting different elastic loops to attach to the braces. The tension provided by the elastic loops corrects the ingrown nail over time without pain to the user.
Patent CA-3063436-A1 (CA)
Inventor: BALTEZOR MICHAEL
IPC: A61K47/02
Filed: 2018-06-13
Abstract: Disclosed herein are compositions and methods for treating lung disorders including lung tumors by pulmonary administration of compositions comprising taxane particles such as docetaxel or paclitaxel particles.
Patent CA-3064537-A1 (CA)
Title: Wireless communication for air data system
Inventor: JHA ASHUTOSH KUMAR
IPC: H04B17/15
Filed: 2019-12-10
Abstract: Systems and methods for operating sensors in an aircraft are provided. Aspects include receiving, by a processor associated with a sensor, a first request to test a transmitter function of the sensor, transmitting a test message to one or more other sensors associated with the aircraft, and listening to a transmitter associated with each of the one or more other sensors to determine a transmitter status of the sensor, wherein the transmitter status of the sensor is a pass status based on receiving a confirmation from at least one of the one or more other sensors. Aspects also include transmitting air data parameters and health status parameters associated with the air data probe to the one or more other air data probes.
Patent CA-3068342-A1 (CA)
Title: Methods and apparatuses for tone mapping and inverse tone mapping
Inventor: NASIOPOULOS PANOS
IPC: H04N19/117
Filed: 2018-06-27
Abstract: A method of producing at least one output image signal representing, at least, a plurality of output luminance values in an output range of luminance values is disclosed. The method involves: identifying a mapping function based at least in part on a perceptually scaled distribution of a plurality of input luminance values in an input range of luminance values different from the output range of luminance values; transforming the plurality of input luminance values into respective perceptually scaled output luminance values according to the mapping function; transforming the perceptually scaled output luminance values into respective ones of the plurality of output luminance values; and producing the at least one output signal representing, at least, the plurality of output luminance values. Computer-readable media and apparatuses are also disclosed.
Patent CA-3070225-A1 (CA)
Inventor: BECKER CHRISTOPHER W
IPC: B28B11/00
Filed: 2018-07-23
Abstract: La présente invention concerne des procédés et des techniques pour générer des produits de bloc de béton préférés. Les procédés et les techniques mettent en uvre l'ajout de couleur à une section sélectionnée dans les blocs (1), selon la description, pour générer des effets d'amélioration. Des applications typiques impliquent des applications de pulvérisation de pigments colorés sur des sections visuellement distinctes du bloc (1) sur une ou plusieurs surfaces décoratives.
Patent CA-3070770-A1 (CA)
Title: Procede et systeme d'affichage base sur des regles d'ensembles d'images a l'aide de parametres derives de contenu d'image
Inventor: WESTERHOFF MALTE
IPC: G16H30/20
Filed: 2018-09-24
Abstract: L'invention concerne un procédé comprenant (a) la sélection d'une étude primaire d'un patient sélectionnée parmi une pluralité d'études ; (b) la sélection, en tant que paramètre A, d'une caractéristique anatomique et/ou d'une caractéristique basée sur une maladie dans l'étude primaire ; (c) l'exécution, sur un processeur de données numériques de serveur, d'un programme de serveur de rendu qui applique une ou plusieurs règles de sélection d'étude (i) pour générer une liste d'une pluralité d'études secondaires sur la base du paramètre A ; (ii) pour générer à partir de la liste de la pluralité d'études secondaires un ou plusieurs paramètres basés sur le contenu d'image à l'aide de réseaux de neurones à convolution (CNN) ; (iii) pour sélectionner parmi la liste de la pluralité d'études secondaires une liste finale sur la base dudit paramètre basé sur le contenu d'image ; (d) l'exécution, sur le processeur de données numériques de serveur, du programme de serveur de rendu qui applique une ou plusieurs règles de sélection de protocole pour sélectionner un protocole d'affichage, où ladite règle de sélection de protocole est basée sur au moins deux paramètres sélectionnés parmi le groupe constitué d'un ou plusieurs paramètres DICOM à partir de l'étude primaire, d'une ou plusieurs étiquettes abstraites à partir de l'étude primaire, d'un ou plusieurs paramètres DICOM à partir de la pluralité d'études secondaires, d'une ou plusieurs étiquettes abstraites à partir de la pluralité d'études secondaires et d'un ou plusieurs paramètres basés sur l'image ; et (e) l'affichage de l'étude primaire et d'une ou plusieurs études secondaires parmi le pluralité d'études secondaires sélectionnées parmi la liste sur la base du protocole d'affichage sélectionné à l'étape (d).
Patent CA-3071749-A1 (CA)
Inventor: OWEN DAVID ALEXANDER
IPC: G01N33/18
Filed: 2018-08-01
Abstract: Carbon dioxide and/or hydrogen sulphide sampling and detection system and method for determination of the content of gaseous CO2 and/or H2S in aqueous liquids, and/or for the fast and reliable detection of the free CO2 gas, HCO3- and/or total carbonate and/or H2S content in aqueous liquids. Said detection system comprises a membrane block having a liquid sample inlet port and a sample outlet port between which a sample flow path extends. Said membrane block comprises a first membrane unit having a sample flow on the first side of a first permeable membrane element and a carrier gas flow on the second side of the first permeable membrane element. Said membrane block further comprises a second membrane unit having a sample flow on the first side of a second permeable membrane element and a carrier gas flow on the second side of the second permeable membrane element. Said first and second membrane units are arranged in series in the liquid sample flow path. The gas flow path is a closed loop that includes gas circulation means, the second gas containing side of the first and second membrane units. The system further comprises a carbon dioxide gas sensor and/or a hydrogen sulphide detection unit, which are arranged in the closed gas circulation loop.
Patent CA-3072976-A1 (CA)
Title: User interface for analysis of electrocardiograms
Inventor: SCABELLONE CHIARA
IPC: G16H50/20
Filed: 2018-08-24
Abstract: The present invention relates to a computer-implemented method for electrocardiogram analysis, the method comprising the steps of receiving at least one ECG signal; analyzing the ECG signal to provide features and/or identify at least one episode and/or event, wherein an episode is a segment of the ECG signal defined by a starting time, a duration and a label obtained during the analysis of the ECG signal and an event is a strip of the ECG signal of predefined duration defined by a starting time and a label obtained during the analysis of the ECG signal; and displaying a multiple field display (1) which includes at least a main plot (42), being a global view of a graphic representation of the ECG signal in a first time window; a local view of a graphic representation of the ECG signal in a second time window (51), where the first time window comprises the second time window; an intermediate view of a graphic representation of the ECG signal in a third time window (52), wherein the third time window comprises the second time window and has a duration comprised between the duration of the first time window and the duration of the second time window.
Patent CA-3073361-A1 (CA)
Title: Modular bio bed and ventilated system for waste water treatment
Inventor: GUSTAFSSON BERT
IPC: C02F3/10
Filed: 2018-09-17
Abstract: In a method for treatment of waste water, a module (5) is used which includes a number of carrier elements (7) arranged in a sandwich structure and configured to be perfused a flow of waste water. The module (5) further has a number of partitions (8) arranged between carrier elements (7) and configured to direct the flow of waste water through the module (5). The module (5) may also be used in a system together with an air supplying device (20) and a waste water vessel. The air is supplied to the module (5) by the air supplying device (20).
Patent CA-3077922-A1 (CA)
Inventor: SMOLJO DRAGOMIR
IPC: E04C5/18
Filed: 2020-04-07
Abstract: Herein is disclosed a system for joining pieces of lumber, the system including a truss plate for attaching the pieces of lumber together and a mounting press for mounting the truss plate onto the lumber. The mounting press includes first and second flat plates with the first flat plate having a rod perpendicularly extending from a central portion thereof and the second plate having a centrally located rod aperture for receiving the rod. The rod is mated to a threaded collar and both are configured to press the first and second flat plates together when the collar is threaded onto the rod. The truss plate consists of a flat piece of metal having a plurality of teeth projecting from one side. An aperture is formed on the plate which is dimensioned to receive the rod.
Patent CA-3078693-A1 (CA)
Title: Riser surge protection system
Inventor: NORDSVEEN MAGNUS
IPC: F16L3/00
Filed: 2018-10-12
Abstract: A system for surge protection of a riser adapted to transport gas from a hydrocarbon production well or for surge protection in a well, the system comprising: a flexible tubing, wherein a portion of the flexible tubing extends into the riser or into the well and wherein the tubing terminates inside the riser or inside the well; a pressure control system arranged to create a pressure differential within the flexible tubing such that liquid is drawn from the riser or the well into the flexible tubing if liquid is present in the riser or the well; wherein the length of said portion of the flexible tubing is variable depending on the amount of liquid drawn into the flexible tubing
Patent CA-3078951-A1 (CA)
Title: Methods for chromatography resin slurry determination
Inventor: MAO NATHAN
IPC: G01F23/292
Filed: 2018-10-15
Abstract: The present invention relates to methods for determining a slurry concentration for a slurry of a chromatography resin during a column packing. The present invention provides a more accurate and consistent method for determining a slurry concentration for packing a chromatography column. The method of the present invention utilizes an automated pump to provide a controlled flow rate to consolidate a resin sample. Based on the consolidated resin, a slurry concentration can be determined. The determined slurry concentration can be utilized to pack the resin in a chromatography column with highly accurate bed heights.
Patent CA-3079876-A1 (CA)
Inventor: LUFT DONALD
IPC: F04B17/06
Filed: 2020-04-30
Abstract: A system to power pressure pumps and auxiliary equipment for oil and gas operations.  The system includes a mobile system controller and energy storage unit electrically connected to pressure pumping and auxiliary loads. The system can also include a power generation source. One application of the technology is to pump fluids to an oil and gas end user which can be an oil or gas well, pipeline or plant. The system can be modularized and can be fully mobile and transportable by a variety of means.
Patent CA-3080792-A1 (CA)
Title: Dnazyme-based sensor for helicobacter pylori
Inventor: BRENNAN JOHN D
IPC: C12M1/34
Filed: 2020-05-15
Abstract: Provided herein are nucleic acid-cleaving catalytic nucleic acid probes, biosensors and lateral flow biosensor devices and methods and kits of using the probes, biosensors and lateral flow biosensor devices for detecting an analyte present on or generated from a microorganism in a test sample, including Helicobacter pylori and methods for determining whether a subject has a Helicobacter pylori infection.
Patent CA-3082370-A1 (CA)
Title: Targeted crispr delivery platforms
Inventor: SONTHEIMER ERIK JOSEPH
IPC: C12N15/79
Filed: 2018-11-09
Abstract: The present invention is related to compositions and methods for gene therapy. Several approaches described herein utilize the Neisseria meningitidis Cas9 system that provides a hvperaccurate CRISPR gene editing platform. Furthermore, the invention incorporates full length and truncated single guide RNA. sequences that permit a complete sgRNA-Nme1Cas9 vector to be inserted into an adeno-associated viral plasmid that is compatible for in vivo administration. Furthermore, Type II-C Cas9 oithologs have been identified that target protospacer adjacent motif sequences limited to between one - four required nucleotides.
Patent CA-3083355-A1 (CA)
Inventor: Musiak Ronald
IPC: H01L41/00
Filed: 2018-07-26
Abstract: An operating point for control of an acoustic transducer can drift during operation and be compensated. A model for the transducer and/or environment frequency response is provided and used to compensate feedback from the transducer to determine an adjustment for the operating point. The model can be recalibrated during operation.