baber/WOPTO huggingface dataset:
Patent EP-4161584-A2 (EP)
Inventor: LU ZHENG-RONG
IPC: A61K49/00
Filed: 2021-06-04
Abstract: A method of detecting drug-resistant cancer in a subject is described. The method includes contacting a tissue of the subject with an effective amount of a molecular probe, detecting the amount of the molecular probe present in the tissue, comparing the amount of molecular probe detected to a control value, and detecting drug-resistant cancer in the subject if the amount of the molecular probe present in the tissue is higher than the control value. The molecular probe includes the following formula: P-L-C wherein P is a EDB-FN targeting peptide, C is a contrast agent; and L is a non-peptide linker that covalently links the peptide to the contrast agent. Methods of monitoring the treatment of drug resistant cancer are also described.
Patent EP-4247394-A2 (EP)
Inventor: KRAEMER BRIAN
IPC: A61K31/712
Filed: 2021-11-22
Abstract: Described herein are small interfering RNA (siRNA) molecules and their use in methods and pharmaceutical compositions for inhibiting the expression of mammalian suppressor of taupathy 2. Also, described herein are the use of said siRNA molecules in the treatment of Alzheimer's disease or dementia, and reducing accumulation of phosphorylated and aggregated human tau.
Patent EP-4026726-A2 (EP)
Inventor: FRIEDRICH JACOB
IPC: B60L53/18
Filed: 2022-01-07
Abstract: A portable electric vehicle supply equipment (EVSE) includes a first line and a second line, a current sensor, a microcontroller, and at least one protective relay. The current sensor is connected to monitor at least one of the first line or the second line and a current module is connected to sample the monitored current. The microcontroller is configured to detect arc faults in the first line and/or the second line based on the sampled current and to selectively open the protective relay in response to a detected arc fault.
Patent EP-4235775-A2 (EP)
Inventor: SUZUKI DAIKI
IPC: H01L23/535
Filed: 2019-10-30
Abstract: The damascene wiring structure includes a base including a main surface provided with a groove, an insulating layer including a first portion provided on an inner surface of the groove and a second portion formed integrally with the first portion and provided on the main surface, a metal layer provided on the first portion of the insulating layer, a wiring portion embedded in the groove and joined to the metal layer, and a cap layer provided to cover the second portion of the insulating layer, an end portion of the metal layer, and the wiring portion. A surface of a boundary part between the first portion and the second portion in the insulating layer opposite to the base includes an inclined surface inclined with respect to a direction perpendicular to the main surface when viewed from the extending direction of the wiring portion. The end portion of the metal layer enters between the cap layer and the inclined surface, and in the end portion, a first surface along the cap layer and a second surface along the inclined surface form an acute angle.
Patent EP-4235938-A2 (EP)
Title: Improved water loss separators used with lead acid batteries, systems for improved water loss performance, and methods of manufacture and use thereof
Inventor: CHAMBERS JEFFREY K
IPC: H01M50/434
Filed: 2016-02-26
Abstract: In at least select embodiments, the instant disclosure is directed to new or improved battery separators, components, materials, additives, surfactants, lead acid batteries, systems, vehicles, and/or related methods of production and/or use. In at least certain embodiments, the instant disclosure is directed to surfactants or other additives for use with a battery separator for use in a lead acid battery, to battery separators with a surfactant or other additive, and/or to batteries including such separators. In at least certain select embodiments, the instant disclosure relates to new or improved lead acid battery separators and/or systems including improved water loss technology and/or methods of manufacture and/or use thereof. In at least select embodiments, the instant disclosure is directed toward a new or improved lead acid battery separator or system with one or more surfactants and/or additives, and/or methods for constructing lead acid battery separators and batteries with such surfactants and/or additives for improving and/or reducing water loss from the battery.
Patent EP-4249171-A2 (EP)
Title: Als knarre verwendbarer drehmomentschlüssel
Inventor: ABEL MICHAEL
IPC: B25B23/142
Filed: 2019-12-09
Abstract: Die Erfindung betrifft ein Schraubwerkzeug mit einem eine Achse definierenden, in einem Gehäuse (1) gelagerten Drehmomentabtriebskörper (4), mit einem eine Vielzahl von Vertiefungen (6) aufweisenden Drehmomentübertragungsabschnitt (5), mit einem von einer Kraft eines Kraftspeichers (19) vorgespannt in zumindest eine der Vertiefungen (6) eingreifenden Drehmomentübertragungskörper (7) zur drehmomentübertragenden Kopplung des Drehmomentübertragungsabschnittes (5) an das Gehäuse (1), welche drehmomentübertragende Kopplung aufgehoben ist, wenn der Drehmomentübertragungskörper (7) flankengesteuert bei Überschreiten eines Grenzdrehmomentes gegen die von einer Einstelleinrichtung (20) einstellbare Kraft des Kraftspeichers (19) die Vertiefung verlässt. Zur gebrauchsvorteilhaften Weiterbildung wird ein von einer Freigabestellung in eine Blockierstellung verlagerbares Umschaltglied (12), welches in der Freigabestellung das Vertiefungsverlassen des Drehmomentübertragungskörpers (7) ermöglicht, in der Blockierstellung aber blockiert, vorgeschlagen.
Patent EP-4252802-A2 (EP)
Inventor: CHERIF-CHEIKH ROLAND
IPC: A61M5/315
Filed: 2018-10-16
Abstract: La présente invention concerne un dispositif d'injection du type comportant un corps (3) cylindrique renfermant un réservoir (5) contenant un produit à injecter, qui est ouvert à une extrémité sur une aiguille d'injection (7) et qui est fermé à son autre extrémité par un piston (9) monté mobile en translation dans le réservoir sous la commande d'une tige de piston (11) pourvue d'un organe de commande (13), ce dispositif comportant des moyens de contrôle de la quantité de produit à délivrer.Ce dispositif est caractérisé en ce que lesdits moyen de contrôle sont disposés sur le corps (3) en une zone se situant hors d'une zone de préhension à pleine main du corps (16).La présente invention concerne également un dispositif de remplissage pour dispositif d'injection.
Patent EP-4306931-A2 (EP)
Title: Methods and systems for cytometry
Inventor: OTA SADAO
IPC: G01N15/14
Filed: 2019-06-12
Abstract: The present disclosure provides methods and systems for ghost cytometry (GC), which may be used to produce an image of an object without using a spatially resolving detector. This may be used to perform image-free ultrafast fluorescence "imaging" cytometry, based on, for example, a single pixel detector. Spatial information obtained from the motion of cells relative to a patterned optical structure may be compressively converted into signals that arrive sequentially at a single pixel detector. Combinatorial use of the temporal waveform with the intensity distribution of the random or pseudo-random pattern may permit computational reconstruction of cell morphology. Machine learning methods may be applied directly to the compressed waveforms without image reconstruction to enable efficient image-free morphology-based cytometry. Image-free GC may achieve accurate and high throughput cell classification as well as selective sorting based on cell morphology without a specific biomarker, which have been challenging using conventional flow cytometers.
Patent EP-4282972-A2 (EP)
Title: Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
Inventor: LEE GRACE J
IPC: C12P7/64
Filed: 2011-05-10
Abstract: Recombinant microbial cells are provided which have been engineered to produce branched chain products such as branched fatty acid derivatives by the fatty acid biosynthetic pathway, and methods of making branched fatty acid derivatives using the recombinant microbial cells.
Patent EP-0002877-A2 (EP)
Inventor: STEEMAN JOHANNES WILHELMUS MAR
IPC: E21B43/26
Filed: 1978-12-30
Abstract: Die Erfindung betrifft ein Verfahren zur Gewinnung von Methan gleichzeitig aus mehreren Flözen, indem oberhalb und unterhalb eines Flözes ein Spaltensystem gebildet und über dieses mit Hilfe von zumindest einem wenigstens teilweise verrohrten Bohrloch Methan abgeführt wird. Von über Tage aus wird bis in ein vorher hierzu bestimmtes Flöz zumindest ein Bohrloch eingebracht, wonach in dem Flöz eine Anzahl durch Kohlenstöße getrennte Hohlräume erzeugt wird, bis die zwischen den Hohlräumen verbliebenen Kohlenstöße und das Hangende unter dem Einfluß des statischen Gebirgsdrucks plötzlich zusammenstürzen. Aus den Räumen, in denen kein hoher Druck herrschen soll, wird das dann freiwerdende Methan über zumindest ein Bohrloch gewonnen. Vorzugsweise wird in den entstehenden Hohlräumen ein Druck aufrechterhalten, der einen Gegendruck zum statischen Gebirgsdruck bildet, und zwar derart, daß die Kohle bei einer bestimmten Breite der Hohlräume und einer bestimmten Breite der zwischenliegenden Stöße nicht hereinbricht. Nach Fertigstellung der Hohlräume wird dieser Druck so weit verringert, daß die Kohlenstöße zu Bruch gehen und das Hangende zusammenstürzt. Die Kohlenstöße können auch mittels Sprengstoff zerstört werden.
Patent EP-0014239-A2 (EP)
Inventor: HAENSSLE PETER DR
IPC: C08F10/02
Filed: 1979-11-24
Abstract: Verfahren zur Herstellung von tertiären 2-Carboxiethyl und Carboximethylphosphinen sowie deren Salze der allgemeinen Formeln P(CH2 - CH2 - COOMe)3 I oder RP(CH2 - COOMe)2 II, wobei Me Wasserstoff, Alkalimetall oder NR'4-Rest mit R' gleich Wasserstoff und/oder Alkyl- oder Arylrest und R ein gegebenenfalls substituierter Arylrest mit 6 bis 14 Kohlenstoffatomen sein kann, indem man die entsprechenden Cyanoalkylphosphine zunachst mit einer wäßrig-alkoholischen Alkalimetallhydroxid-Lösung verseift, dann die wäßrige Lösung der Säuresalze mit einem sauren Ionenaustauscher behandelt und die freien Sauren gegebenenfalls mit einem Alkalimetallhydroxid oder Ammoniak bzw. einem Amin neutralisiert. Die so hergestellten tertiaren 2-Carboxiethyl- und Carboximethylphosphine finden Verwendung als Katalysatorbestandteil bei der Oligomerisierung von Ethylen mit Hilfe eines Nickelkatalysators.
Patent EP-0022423-A2 (EP)
Title: Vorrichtung zur Aufbereitung von Rohwasser, beispielsweise Oberflächenwasser, Abwasser oder dergleichen im Wege der Sedimentation
Inventor: MOLL HANS-GEORG DR
IPC: C02F1/52
Filed: 1980-03-19
Abstract: Die Erfindung bezieht sich auf eine Vorrichtung zur Wasseraufbereitung im Wege der Sedimentation, bei der das mit dem Flockungshilfsmittel versetzte Wasser tangential einem zylindrischen Behälter zugeführt wird. Durch eine mit Durchbrechungen versehene Zwischenwand wird die Strömungsgeschwindigkeit des Wassers so weit abgebremst, daß in dem Behälter keine aufwärts gerichteten Sekundärströmungen entstehen, so daß die gebildeten Flocken sich nach unten in dem Behälter absetzen, und das gereinigte Wasser durch ein mittig im Behälter angeordnetes Rohr nach unten abgeführt wird. Die Wirkungsweise der Vorrichtung wird dadurch verbessert, daß koaxial zum Abflußrohr ein dieses unter Bildung eines Ringspaltes umgreifendes und übergreifendes Zusatzrohr angeordnet ist, das über siene Länge verteilte waagerechte Ringschlitze besitzt. Durch diese Ringschlitze wird erreicht, daß im Behälter das Wasser dem Zusatzrohr in waagerechter Richtung zufließt, und die Aufwärtsströmung des abfließenden Wassers erst in dem Ringspalt erfolgt. Hierdurch können sich auch kleinere Flokken nach unten absetzen, so daß diese nicht in das Reinwasser gelangen können.
Patent EP-0036472-A2 (EP)
Inventor: ZABLOCKI MARIAN
IPC: C10L1/32
Filed: 1981-01-21
Abstract: The fuel contains a liquid hydrocarbon fuel or another liquid, carbon black as a technical-grade amorphous form of elemental carbon, in the form of a suspension in the liquid phase, and chemical stabilising agents (dispersants).
Patent EP-0071882-A2 (EP)
Inventor: BORNER ROLAND
IPC: B24B3/16
Filed: 1982-07-28
Abstract: A scanning finger for a scanning device of a machine for automatically sharpening tools has a horizontal slide for receiving a tool to be ground and a vertical slide carrying at least one grinding spindle. The scanning finger has a scanning face, which is substantially horizontal and limited by and undercut to rest on the free face of a tool tooth to be ground, as well as a face which is downwardly offset from the scanning face and is intended for ascertaining the cutting face of the tooth. In order to make it possible to scan the cutting face at a distance from the original cutting edge, the face for ascertaining the cutting face of the tooth is undercut in the direction of movement of the horizontal slide and below the horizontal scanning face, and below the undercut it has a measuring edge to rest on the cutting face.
Patent EP-0072943-A2 (EP)
Inventor: HENZE WERNER ING-GRAD
IPC: H03J7/18
Filed: 1982-08-05
Abstract: In this system, a site determination is effected, according to the invention, by evaluating the identification data in the case of transmitters which radiate identification data and by comparing the received transmitters with a table of receivable transmitters stored in a memory in the case of transmitters which do not radiate any identification data, the evaluation of the identification data having priority. <IMAGE>
Patent EP-0060088-A2 (EP)
Inventor: MUHLER JOSEPH CHARLES
IPC: A61K8/24
Filed: 1982-03-04
Abstract: A chewing gum is disclosed which is for cleaning and imparting a high degree of polish to the teeth; the chewing gum comprises a chewing gum base. at least one non-toxic source of acid in a particular amount, and calcined kaolin particles, the median diameter of which is approximately 2 micrometres or less, and substantially all of the particles being less than approximately 20 micrometres in diameter. Such a chewing gum cleans and imparts a high degree of polish to the teeth without unduly abrading or scratching them. When regularly chewed, such a gum, in addition to cleaning and polishing the dental enamel. can also inhibit the reformation of dental plaque.
Patent EP-0060671-A2 (EP)
Inventor: HAYASHI MASUMI
IPC: B29C65/00
Filed: 1982-03-09
Abstract: A metal wire-containing polymeric laminate tape is continuously produced by superimposing a pair of primary cross- linked, electro-insulating thermoplastic polymer tapes face to face along the longitudinal axes thereof under tension, while a plurality of metal wires are interposed, under tension, in paral- lei to each other, between the primary tapes along the longitudinal axes thereof; by heating the resultant precursory laminate tape up to a temperature of from 10 to 120°C above the melting point of the corresponding thermoplastic polymer which is not cross-linked; by pressing the heated precursory laminate tape by using a pair of elastic pressing rolls, whereby the primary tapes are heat-bonded together to provide a body of laminate matrix within which the metal wires are embedded; and, optionally, by cooling the resultant laminate tape.
Patent EP-0074717-A2 (EP)
Inventor: WISSMAN TERRY L
IPC: B30B15/04
Filed: 1982-08-10
Abstract: A guiding arrangement for the reciprocating slide 56 of a mechanical press includes guideposts 58 which are rigidly connected to the crown 20 of the press and depend downwardly therefrom, passing through guide bushings 66 in the slide assembly. The crown 20 is connected to the bed of the press by uprights 18. In order to counteract the non-vertical forces exerted on the slide by connection arms extending from a crankshaft in the crown and pivotally connected to pistons connected to the slide and moving in cylinders fixed to the crown, which forces tend to cause the slide to tilt about a horizontal axis perpendicular to the axis of the crankshaft, hydrostatic bearings are mounted between each piston and cylinder to exert restraining forces in a direction perpendicular to the axis of reciprocation of the slide and along lines which intersect the axis of rotation of the pivotal connections to the pistons.
Patent EP-0057136-A2 (EP)
Inventor: ROLIN GUY
IPC: G05B19/427
Filed: 1982-01-21
Abstract: Dans ce tour de repoussage, l'effort exercé par la molette (6) sur la pièce à travailler est constamment surveillé par un ou plusieurs capteurs d'effort (22) qui fournissent un signal instantané d'effort à une boucle d'asservissement commandant le mouvement de la molette (6) dans une direction transversale à l'axe de rotation du tour. Ce signal de consigne de la boucle est engendré par un générateur qui peut être à action manuelle ou à fonctionnement programmé automatique. La boucle commande l'effort de la molette (6) grâce à un vérin (13) alimenté à travers une vanne asservie (43).
Patent EP-0059669-A2 (EP)
Inventor: URBANIC JOHN E
IPC: C13B20/12
Filed: 1982-02-26
Abstract: A process for the purification of sugar liquors with activated carbon is described. The use of activated carbon with an iodine number at least 1000 and an average particle size in the range of 0.4 mm to 4.0 mm allows for increased flow rates resulting in high yield of purified sugar liquors.
Patent EP-0060186-A2 (EP)
Inventor: VINDEZ PIERRE G
IPC: B23Q5/32
Filed: 1982-03-02
Abstract: In a positive feed power drill having a spindle drive gear train and a spindle feed gear train, where a single motor drives both gear trains through separate coupling gears on a common shaft that are engaged while the spindle is advanced to drill through a work piece, and having means for disengaging the feed coupling gear to automatically retract the spindle, provision is made for field adjustment of the differential in the gear ratios of the gear train to adjust the feed rate relative to the drive rate for a particular work-piece material by removing a cap directly over the common shaft for the coupling gears, and replacing at least one of the coupling gears with a gear of the same diameter, tooth height and pitch, but a different number of teeth. The profile of the teeth is modified as the number of teeth is increased, or decreased, in order that smooth meshing of the teeth will be assured with adjacent gears which are not changed.
Patent EP-0085351-A2 (EP)
Inventor: IIDA KAZUHIKO
IPC: H04N1/32
Filed: 1983-01-18
Abstract: A picture information display device having a control circuit (1) for determining a reductive ratio which is set in a size converting circuit (14) in accordance with the size of an original and the size of a display area at a display unit (16). ' The size converting circuit (14) reduces the size of the picture information read out from a page buffer memory (5) of the control circuit (1) in accordance with the reductive ratio. The readout picture information is stored in a refresh memory (60) of a display interface (15). The display unit (16) displays the size-reduced picture information of the refresh memory (60). The reductive ratio is so selected that the picture information stored in the refresh memory (60) is displayed over the entire region of a display area of the display unit (16)
Patent EP-0092735-A2 (EP)
Inventor: GLANZ RICHARD
IPC: B65H23/038
Filed: 1983-04-13
Abstract: The web guide apparatus of the present invention includes a sationary tilt roller support frame, a pivotal tilt roller support means and an inlet tilt roller. A web of material travelling in a direction generally perpendicular to the tilt roller is guided by arcuately pivoting the tilt roller with respect to the direction of travel of the web. 
     The pivotal frame of the apparatus is supported upon the stationary frame by means of a rolling engagement bearing carriage. The center about which the tilt roller is pivoted. known as the origin of radius, lies on the line defined by the inlet edge of the inlet tilt roller.
Patent EP-0095639-A2 (EP)
Inventor: BUCKLER ROBERT T
IPC: G01N33/542
Filed: 1983-05-16
Abstract: Propanol immunogens which are 3-(1-naphthoxy)-2-hydroxypropylamine and 3-N-[2-hydroxy-3-(1-naphthoxy)-1-propyl] aminobutyric acid coupled to an immunogenic carrier; antibodies prepared therefrom, a labelled conjugate of 3-N -[ 2-hydroxy-3-(1-naphthoxy)-1-propyl] aminobutyric acid intermediates; an immunoassay method; a test kit and test device.
Patent EP-0098502-A2 (EP)
Inventor: BEST WALTER DR
IPC: D21F1/00
Filed: 1983-06-28
Abstract: A belt to be used in paper-machine wet-pressing, in particular in a machine with an extended pressing gap, includes a flexible, liquid-impermeable belt stratum which is smooth on its back side. This belt is improved by providing the front side of the belt stratum (2,12,25,36) with a structured surface with open longitudinal and/or transverse channels (9,14,30,41), for the purpose of water drainage, which cannot be squeezed, or only insignificantly, under press compression.
Patent EP-0108196-A2 (EP)
Inventor: FARBER ERNST-OVE DIPL-ING FH
IPC: B65D88/54
Filed: 1983-07-28
Abstract: Silo for storing solidify loose material, especially flue ash, which has a conveyor which can be moved on the surface of the stored material and which feeds the material loosened there to a conveyor device located in the silo which brings it to an exit opening provided on the silo floor. This conveyor device is simply and effectively constructed in accordance with the invention by forming it by a falling series of aeration devices on an essentially vertical silo wall. This silo wall is advantageously the circumference of a column provided in the center of the silo. In a first embodiment the mechanically separated and pneumatically loosened material passes through slideless openings into the inner space in the column, from which it is removed at the bottom. In a second embodiment the aeration devices are arranged on the circumference of the column in such a compact series that they result in the formation of an emptying column which follows the column surface and is filled by material fluidized by aeration.
Patent EP-0109671-A2 (EP)
Inventor: NOBS ERWIN
IPC: G09F13/26
Filed: 1983-11-18
Abstract: L'élément émetteur de lumière (24) disposé en lignes et en colonnes constitue l'élément unitaire dont est équipé le tableau d'affichage matriciel. L'élément comprend un ou plusieurs tubes à décharge (10, 11, 12). Pour un tableau restituant des images (texte ou vidéo) en couleur, la paroi interne de chacun des tubes est revêtue d'une substance fluorescente qui rayonne une couleur rouge, verte et bleue respectivement. En variant indépendamment l'intensité de la lumière émise par chacun des tubes colorés, on obtient à la sortie de l'élément (24) une lumière dont la longueur d'onde résultante peut s'étendre sur tout le spectre visible. L'invention peut être utilisée sur un tableau d'affichage disposé par exemple dans un stade ou lors de manifestations impliquant un grand nombre de personnes.
Patent EP-0146654-A2 (EP)
Inventor: DAVIS PAUL JAMES
IPC: G01N33/543
Filed: 1981-06-22
Abstract: A process for carrying out a specific binding assay (for example an immunoassay) in which (a) a sample under assay, possibly containing a substance being tested for, is reacted with (b) a specific binding partner for the substance being tested for, immobilised on a solid support, and (c) a specific binding partner for the substance being tested for which is conjugated to a detectable marker, thereby to form a complex by reaction between whatever quantities are present of the substance being tested for with reagents (b) and (c), in which the marker is immobilised to the support via the substance being tested for, and is detected or assayed as an index of the quantity present in the sample (a) of any of the substance being tested for; characterised in that reaction ingredients (a), (b) and (c) are all mixed in a single step for reaction in a single reaction liquid, and competitive interference between the binding reactions of the substance being tested for and reagents (b) and (c) is avoided either by use of an antibody of narrow and different, non-interfering specificity, such as a monoclonal antibody, to avoid the interference, or by use of a slow-release form of reagent (c).