baber/WOPTO huggingface dataset:
Patent WO-9843657-A2 (WO)
Title: Graminaenpollenallergenmutanten zur spezifischen immuntherapie, deren herstellung und verwendung
Inventor: KAHLERT HELGA
IPC: A61K36/899
Filed: 1998-03-16
Abstract: Die Erfindung betrifft modifizierte rekombinante Allergenmutanten, die aus rekombinanten Allergenen, abgeleitet von Allergenen, die durch Extraktion aus natürlichen Rohstoffen, wie z.B. Pollen der Spezies Phleum pratense gewonnen werden können. Diese modifizierten rekombinanten Allergene stimulieren Lymphozyten von Pollenallergikern zur Proliferation und Zytokinsynthese, weisen jedoch mit den im Serum der T-Lymphozytenspender enthaltenen lgE-Antikörper sowie mit Graspollenallergen-spezifischen lgE eine deutlich verminderte Bindungsfähigkeit auf und sind daher für eine spezifische, maßgeschneiderte Allergie-Therapie verwendbar.
Patent WO-9914231-A2 (WO)
Inventor: FORSSMANN WOLF-GEORG
IPC: C07K7/06
Filed: 1998-09-16
Abstract: Peptide erhältlich durch Versetzen von Kuhmilch oder Humanmilch mit Proteasen und anschließender Inkubation für zwei Stunden, Zentrifugation, um Michfett zu entfernen, Ansäuern auf einen pH von 2,0 durch starke Säuren, Abtrennung der ausgefallenen Proteine, Anwendung mindestens eines Reverse-Phase-HPLC-Schrittes, Anwendung eines Kationenaustauscher-HPLC-Schrittes, Sammeln von Fraktionen, Einstellen der Fraktion auf einen Salzgehalt < 25 mM für die Durchführung von Aktivitätstests durch Dialyse oder Reverse-Phase-HPLC, Kultivierung von Bifidobakterium Bifidum und E. coli in Gegenwart der Fraktionen und Auswahl von Fraktionen, die der Bedingung: BW/B0 - EW/E0≥0,15 (bifidogen) genügen, worin BW die Keimzahl bezeichnet, die bei 16-stündiger Inkubation von Bifidobakterium Bifidum in 50 % Elliker Broth in Gegenwart der Peptide in einer Konzentration von 200 νg/ml erhalten wird, B0 die Keimzahl bezeichnet, die bei der wirkstofffreien Kontrollinkubation erhalten wird, EW die Keimzahl bezeichnet, die bei 16-stündiger Inkubation von E. coli in 3 g/l Tryptic Soy Broth in Gegenwart der Peptide in einer Konzentration von 200 νg/l erhalten wird, E0 die Keimzahl bezeichnet, die bei der wirkstofffreien Kontrollinkubation erhalten wird, Isolierung des in dieser Fraktion vorhandenen Peptids sowie die amidierten, acetylierten, sulfatierten, phosphorylierten, glycosylierten, oxydierten Derivate oder Fragmente mit bifidogenen Eigenschaften und Peptide, die durch Kombination der Peptide, Fragmente oder Derivate mittels chemischer Verknüpfung erhältlich sind.
Patent WO-0037594-A2 (WO)
Title: In fester form konfektionierte hydrophobe flüssigkeiten für den einsatz in wasch- und reinigungsmitteln mit hohem schüttgewicht
Inventor: PAATZ KATHLEEN
IPC: C11D17/00
Filed: 1999-12-11
Abstract: Bei einem Verfahren zur Herstellung von granularen Wasch- oder Reinigungsmitteln mit hohem Schüttgewicht durch strangförmiges Verpressen über Lochformen und anschließendes Zerkleinern des Extrudats mittels einer Schneidevorrichtung sollte die Einarbeitbarkeit hydrophober flüssiger Komponenten verbessert werden. Dies gelingt im wesentlichen dadurch, daß man die hydrophobe Flüssigkeit in Dextrin verkapselt.
Patent WO-9732038-A2 (WO)
Title: Diagnostic des mammites base sur des sequences specifiques d'adn dans le lait
Inventor: ALATOSSAVA JOUKO TAPANI
IPC: C12Q1/68
Filed: 1997-02-26
Abstract: L'invention concerne une méthode de diagnostic rapide des mammites, basée sur l'identification d'une séquence d'ADN. Cette méthode consiste à rechercher dans le lait la présence des séquences d'ADN suivantes: séquences d'ADN spécifique de cellules somatiques indiquant une inflammation, séquence d'ADN spécifique de l'agent pathogène responsable de la mammite indiquant une infection et séquence d'ADN spécifique du gène du pathogène, codant pour la résistance aux antibiotiques. Cette information facilite le choix du traitement à mettre en oeuvre. L'invention concerne également des trousses d'essai et des oligonucléotides spécifiques du genre ou de l'espèce, ainsi que leur utilisation dans le cadre de ladite méthode.________________________________________________________
Patent WO-02067738-A2 (WO)
Title: Device for loading slices of bread in a toaster
Inventor: ROUSSEAU ALAIN
IPC: A47J37/08
Filed: 2002-02-20
Abstract: An automatic toaster, comprising heating means (2) with slices of bread pass passing in front of said heating means, and means for transporting slices of bread to said heating means, characterized in that the means for transporting the slices of bread include a spiral-shaped rotating element (6) defining a plurality of housings (11) for slices of bread (30), the length of said housings corresponding essentially to the pitch of the spiral (6).
Patent WO-02088735-A2 (WO)
Title: Method for depositing a spot of a product of interest, and use for isolating and/or determining an analyte
Inventor: PERRIN AGNES
IPC: G01N33/543
Filed: 2002-04-25
Abstract: The invention concerns a method for depositing on a substrate (1) a product of interest (2), in a small elementary surface (3), called spot, which consists in: a) preparing or providing a liquid medium (4) comprising a carrier and the product of interest (2); (b) from the liquid medium, forming a drop (5), and setting said drop on the surface (1a) of the substrate, in contact with the liquid medium; (c) eliminating the carrier of the drop (5), for example by drying, so as to allow said spot to remain. The invention is characterised in that it consists, in combination, in: (1) preparing or providing a magnetic support (6), distributed in the carrier; (2) binding the product of interest (2) to the magnetic support (6), so that the liquid medium, wherefrom the drop (5) is formed, comprises transport particles (7); (3) at least while eliminating the carrier of the drop (5), generating a magnetic field (8) passing through the surface (1a) of the substrate (1), so that the resulting spot (3) comprises the transport particles, and hence the product of interest.
Patent WO-03045399-A2 (WO)
Title: Composition based on diosgenin ester for topical use
Inventor: EYMARD MICHELE
IPC: A61K31/58
Filed: 2002-11-18
Abstract: The invention concerns compositions useful in therapeutics and in cosmetology. The composition comprises a diosgenin ester with linear or branched alkylated ester chain containing 1 to 30 carbon atoms selected preferably among diosgenin lactate and glycolate. The invention is applicable in dermatology by acting on the superficial musculo-aponevrotic system or on estrogen and progesterone cell receptors.
Patent WO-2004004096-A2 (WO)
Title: Internal ventilating system for a rotating electrical machine such as a motor vehicle alternator
Inventor: VASILESCU CLAUDIU
IPC: H02K9/06
Filed: 2003-06-30
Abstract: The invention concerns a rotating electrical machine, comprising inside a housing, a fixedly mounted stator and a rotor rotatably mounted in the stator, the ventilating system including in particular at least one ventilator integral with the rotor and capable of generating a cooling air stream inside the housing, radial air intake orifices (20) arranged in the housing, and cooling air discharge ports (22) arranged in said housing in a ring opposite the periphery of the ventilator and mutually separated by fins (24) stiffening the housing in the port region. The system is characterized in that the angle of inclination of the fins (24) relative to the tangent perpendicular to the radial direction (R) ranges between 38° and 52°. The invention is for use for motor vehicle alternators.
Patent FR-2364405-A2 (FR)
Title: Steam boiler and condenser system - has buffer tank for condenser and fresh water supplies with level sensors
IPC: F22D5/00
Filed: 1976-09-13
Abstract: The water supply system for a steam boiler (8) has feed water supplied to the boiler from a buffer tank (14) fed by fresh water. The feed water circulates through a pump-driven (17) loop (88) which includes the buffer tank and a heater (84). The boiler has a water level sensor (37) automatically connecting (46) the loop to the boiler. The buffer tank also has a water level sensor (53) which automatically starts a pump in order to supply fresh water to the buffer tank. A second, high pressure buffer tank may be included between the first buffer tank and the boiler.
Patent FR-2460606-A2 (FR)
Title: Powered thresher machine for cereals - has thresher drum with replaceable convex strips and agitator fingers over mesh separator drum
Inventor: BRILLAUD EDMOND
IPC: A01F11/00
Filed: 1979-07-10
Abstract: The thresher comprises a thresher drum (7) made from convex strips (56) attached to end plates with flat strips (108) between the convex strips. All strips are replaceable. A segmental curved plate (8) follows part of the thresher drum profile, from the pressure roller (4) to discharge onto the paddle type feeder (11). The cereals pass over agitator fingers (98), which oscillate vertically, and fall onto a mesh separator drum (16). A fan (13) separates the grain from the chaff, its shaft (93) also driving (94,97) the agitator fingers. The grain is then discharged (35), separate from the chaff.
Patent FR-2465794-A2 (FR)
Title: Placage multicouche pour donner a un support de metal ferreux une resistance a la corrosion amelioree
Inventor: HYNER JACOB
IPC: C23C28/02
Filed: 1980-09-24
Abstract: PLACAGE MULTICOUCHE POUR CONFERER UNE RESISTANCE AMELIOREE A UN SUPPORT EN METAL FERREUX. UN TEL PLACAGE COMPREND: A.UNE SOUS-COUCHE EN UN ALLIAGE DOUE DE POUVOIR DE "MICRO-PROJECTION" DEPOSEE DIRECTEMENT SUR LEDIT SUPPORT EN METAL FERREUX, ET B.AU MOINS UNE COUCHE EXTERIEURE DE REVETEMENT METALLIQUE OU ORGANIQUE CONTRIBUANT A L'AMELIORATION DE LA RESISTANCE A LA CORROSION DUDIT METAL FERREUX.
Patent FR-2622896-A2 (FR)
Title: Process for the manufacture of an expanded structure the main part of which is made of leather and structure obtained by this process
IPC: C14B7/02
Filed: 1987-11-10
Abstract: Process for the manufacture of an expanded structure the main part of which is made of leather and the straps of which are situated in the same plane and together form perfectly uniform meshes. This process is characterised in that the skin or sheet of leather is impregnated with a resin or an adhesive in sufficient quantity for the excess part, which is not absorbed by the pores of the skin, to form under the latter a thin film or sheet of resin or of adhesive forming an underlayer, and the resin or the adhesive is chosen with a nonelastic character and without memory so that the underlayer thus formed remains open after expanding and resists the retraction of the skin or of the sheet of leather with which it is intimately bound.
Patent WO-0037607-A2 (WO)
Inventor: GROS JEROME
IPC: C12N5/02
Filed: 1999-12-17
Abstract: L'invention concerne une méthode de production d'adipocytes à partir de fibroblastes non différenciés caractérisée par la mise en culture de fibroblastes non différenciés arrivés à confluence et exprimant de manière stable le récepteur adrénergique β3 humain ou le récepteur adrénergique β3 humain muté W64R, dans un milieu comprenant des agents stimulant la différenciation des adipocytes.
Patent WO-0188679-A2 (WO)
Title: Systeme de navigation et procede d'utilisation associe
Inventor: WALLEN LINCOLN
IPC: G06T19/00
Filed: 2001-05-11
Abstract: L'invention concerne un système de navigation (1) permettant d'afficher de manière spatiale des informations sur un navigateur (1) qui peut être déplacé par un utilisateur, par exemple, un navigateur de poche tel qu'un assistant personnel numérique ou un téléphone cellulaire. Le navigateur détermine sa position et son orientation, puis il calcule la vue du monde virtuel en fonction de la position et de l'orientation du navigateur et de la position présumée de l'oeil de l'utilisateur. La vue correspondante est projetée sur l'écran du navigateur. Le déplacement ultérieur du navigateur permet d'obtenir la commande du défilement et de l'agrandissement des informations affichées de manière spatiale.
Patent WO-0249105-A2 (WO)
Title: Thermoelectric spot coolers for rf and microwave communication integrated circuits
Inventor: GHOSHAL UTTAM SHYAMALINDU
IPC: H01L23/522
Filed: 2001-12-11
Abstract: An apparatus for cooling selected elements within an integrated circuit, such as active transistors or passive circuit elements used in a radio frequency integrated circuit is provided. In one embodiment, the cooling apparatus includes a cold plate thermally coupled to the region proximate the integrated circuit element, a thermoelectric cooler thermally coupled to the cold plate; and a hot plate thermally coupled to the thermoelectric cooler. Heat is removed from the integrated circuit element through the cold plate and transmitted to the hot plate through the thermoelectric cooler. In one form, the hot plate is located or coupled to an exterior surface of an integrated circuit, such that heat transmitted to the ambient from the integrated circuit element is dissipated into the atmosphere surrounding the integrated circuit. In another form, the hot plate is embedded in the integrated circuit substrate to locally cool elements of the integrated circuit while dumping the heat into the substrate.
Patent WO-03038482-A2 (WO)
Title: Filtre accordable
Inventor: SMITH GILBERT WILLIAM
IPC: G02B26/00
Filed: 2002-10-23
Abstract: L'invention concerne un filtre accordable comprenant : au moins deux filtres Fabry-Pérot couplés, chaque filtre Fabry-Pérot présentant un spectre de transmission Fabry-Pérot comprenant une pluralité de crêtes. Ledit filtre accordable comprend de plus un module d'accord servant à modifier au moins un des spectres Fabry-Pérot, jusqu'à ce qu'une coïncidence substantielle soit obtenue entre au moins deux crêtes choisies dans chacune dans un spectre Fabry-Pérot, chacun desdits filtres comprenant une cavité d'épaisseur optique différente.
Patent WO-9808125-A2 (WO)
Inventor: BOLT SIDNEY JOSEPH
IPC: G02B6/24
Filed: 1997-08-21
Abstract: An optical fibre splice closure, comprising: (a) a casing for containing a plurality of optical fibre splices; (b) a support which, at least in use, is contained in the casing and on which, in use, a plurality of optical fibre splices are located; and (c) sealant which, at least in use, is contained in the casing and encapsulates at least part of the support.
Patent HR-P920389-A2 (HR)
Title: Equipment for cleaning centrifugal separators
Inventor: AJNEFORS FREDERIK
IPC: B04B/
Filed: 1992-09-21
Abstract: PCT No. PCT/SE88/00532 Sec. 371 Date Apr. 3, 1990 Sec. 102(e) Date Apr. 3, 1990 PCT Filed Oct. 13, 1988 PCT Pub. No. WO89/03251 PCT Pub. Date Apr. 20, 1989.The internal cleaning of a centrifuge rotor is performed by a cleaning liquid is which pumped from a tank via an inlet channel to a central inlet chamber of the rotor during rotation thereof. A separation chamber is connected to the inlet chamber and, at different radial levels, to two outlet chambers via separate outlet passages. Cleaning liquid is discharged from the outlet chambers through a stationary discharge device having separate outlet channels. Part of the cleaning liquid discharged through the outlet channels is returned to the tank via a return conduit. The rest of the cleaning liquid is conducted directly to the inlet channel by means of an overpressure generated in the stationary discharge device. Thereby, it is possible to clean the rotor internally even very close to its rotational axis.
Patent HU-0000222-A2 (HU)
Title: Circular sewing machine with wave-like sewing surfice
Inventor: DR CSIKY LASZLO
IPC: A61B17/11
Filed: 2000-01-24
Abstract: A surgical stapling instrument comprises a frame having a body portion and a handle. A staple fastening assembly is provided in the distal region of the instrument and includes a cartridge device (5), which comprises at least one closed row of staples, and an anvil (1). The anvil (1) is moveable relative to the cartridge device (5) and is adapted to cooperate with the cartridge device (5) for forming the ends of the staples exiting from the cartridge device (5). A knife (7), which has a closed cutting edge, is contained within the cartridge device (5) and is positioned such that there is at least one closed row of staples on the outside of the cutting edge. It can be moved towards the anvil (1). The line defining the closed row of staples has a wavy shape (6, 2), leaving a plane perpendicular to the longitudinal axis of the staple fastening assembly, such that the line defining the closed row of staples has a larger total length than the projection of this line onto said plane. This provides greater flexibility of the anastomotic side and less tension during instrument removal, alleviating the incidence of clinical complications.
Patent HU-0000302-A2 (HU)
Inventor: HECHT RANDY IRA
IPC: A61K38/17
Filed: 1997-12-11
Abstract: A jelen találmány Fc fúziós prőteinkészítményekkel, az ilyen,készítmények előállítására szőlgáló módszerekkel és ezekalkalmazásával kapcsőlatős. Részletesebben, a jelen találmány az OBprőtein vagy származék, vagy analóg N-terminális részéhez fűziőnált Fcimműnőglő-bűlin régiót vagy származékőt, vagy analógőt tartalmazó,genetikai vagy kémiai prőteinnel kapcsőlatős. ŕ
Patent HU-0002022-A2 (HU)
Title: Process for the fermentative production of l-amino acids and nucleotide sequences coding for the accda-gene
Inventor: EGGELING LOTHAR DR
IPC: C12N15/54
Filed: 2000-05-26
Abstract: Cloned Corynebacterium glutamicum DNA (I), replicable in coryneform microorganisms coding for an accDA gene having a fully defined 2123 bp sequence (given in the specification(), is new. Independent claims are also included for the following: (1) a polypeptide derived from (I) having a fully defined 491 aa sequence (given in the specification); (2) coryneform microorganisms transformed with one or more copies of (I); (3) the shuttle vector pZ1accDA contained in Corynebacterium glutamicum DSM 12785; and (4) a process for producing L-amino acids, comprising culturing a coryneform bacterium that overexpresses the accDA gene.
Patent HU-0002574-A2 (HU)
Title: Gas-tank and vehicular, and process for distributing liquefied natural gases from land-based basic-station
Inventor: BOWEN RONALD R
IPC: F25B19/00
Filed: 1998-06-18
Abstract: A container (10) suitable for a tanker truck for transporting pressurized liquified natural gas (PLNG) at a pressure of between 1035 and 7590 kPa and a temperature of between -123 to -62[deg]C, constructed from an ultra-high strength low alloy steel containing less than 9% wt nickel and with a tensile strength greater than 830 MPa and a ductile to brittle transition temperature (DBTT) lower than about -73[deg]C. A container for a tanker truck constructed by joining together several discrete plates of said ultra-high strength low alloy steel, where the joints have a tensile strength greater than about 900 MPa and a DBTT lower than about - 73[deg]C. A tanker truck for transporting PLNG including at least one container constructed as above. A method of transporting PLNG at these pressures and temperatures by (a) transporting the PLNG in a tanker truck with at least one storage container as above, and (b) delivering the PLNG to a destination site with storage containers made of an ultra-high strength low alloy steel containing less than 9% nickel and with a tensile strength greater than 830 kPa and a DBTT lower than about -73[deg]C. A system for transporting PLNG using at least one such tanker truck.
Patent HU-0004615-A2 (HU)
Title: Polypropylene composition useful for making solid state oriented film
Inventor: NGUYEN TINH N
IPC: B65D65/02
Filed: 1999-07-29
Abstract: Disclosed is a polypropylene composition useful for making solid state oriented film. The composition comprises two predominantly isotactic polypropylenes with the melting point temperature of one of the polypropylenes being substantially lower than the melting point temperature of the other. In one embodiment of the composition the higher melting point polypropylene is made by Ziegler-Natta catalysis, while the lower melting point polypropylene is made by metallocene catalysis. Compared to polypropylene with similar melt flow rate and made by Ziegler-Natta catalysis, and solid state oriented film thereof, the composition provides a better balance of elevated temperature draw characteristics and physical properties of oriented film made therefrom. Thus, at the same or lower elevated temperature yield stress, oriented film of the composition exhibits improved properties such as stiffness, elongation-at-break, dimensional stability, and oxygen barrier. Also disclosed is a method for the manufacture of oriented, flexible packaging film. In the method a cast sheet is melt extruded from the composition, and, after cooling until it is solid, the cast sheet is stretched to the desired extent of orientation at a temperature which the sheet does not break while being stretched, but below the Tm of the composition. The resulting film then is cooled to at least the crystallization temperature of the lower melting point polypropylene.
Patent HU-0101275-A2 (HU)
Inventor: ITO TAKAO
IPC: C07C235/42
Filed: 1999-03-23
Abstract: A találmány tárgya az (1') általános képletű vegyület, ahol aképletben R2 jelentése kis szénatomszámú alkilcsoport, amely kívántesetben hidroxilcsoporttal, aminocsoporttal és hasonlókkalhelyettesített, a B gyűrű jelentése fenilcsoport, tienilcsoport éshasonlók, E jelentése vegyértékkötés, -O- atom, -S- atom és hasonlók,a G gyűrű jelentése arilcsoport, heterociklikus csoport és hasonlók,R5 jelentése halogénatom, hidroxilcsoport, kis szénatomszámúalkilcsoport, amely kívánt esetben halogénatommal és hasonlókkalhelyettesített, t jelentése 0 vagy jelentése 1-5 közötti érték, ha tjelentése 2-5 közötti érték, akkor minden egyes R5 jelentése azonosvagy egymástól eltérő, m jelentése 0 vagy 1-8 közötti érték, és njelentése 0 vagy 1-4 közötti érték, és az (1') általános képletűvegyületet hatóanyagként tartalmazó nociceptin antagonista. Az (1') általános képletű vegyület a nociceptin antagonista hatásakövetkeztében fájdalomcsillapító hatást fejt ki erős fájdalmakkal, ígyposztoperatív fájdalmakkal és hasonlókkal szemben. A jelen találmánytárgya továbbá az (1') általános képletű vegyületek körébe tartozóbizonyos amidszármazékok, melyek nociceptin antagonisták vagyfájdalomcsillapítók. Ó
Patent HU-0104392-A2 (HU)
Inventor: AUSUBEL FREDERICK M
IPC: C07K14/415
Filed: 1997-08-08
Abstract: A találmány tárgyköre a génsebészet, növénybiológia, növényi patogénekelleni védőgének és azok által kódolt fehérjék, valamint termésvédelemterületére esik. A találmány tárgyát közelebbről, szerzettrezisztenciáért felelős polipeptideket kódoló gének, a géneket hordozótranszgenikus növények és ezek szaporítóanyagai képezik. A találmánytárgyát képezik továbbá a találmány szerinti gének által kódoltpolipeptidek, valamint eljárások szerzett rezisztenciáért felelősgének izolálására. A találmány szerinti megoldás alkalmas kártevőknekfokozottan ellenálló haszonnövények előállítására. Ó
Patent HU-0105089-A2 (HU)
Inventor: DONGA ROBERT
IPC: A61K/
Filed: 1999-11-19
Abstract: A találmány gyorsan diszpergálódó szilárd készítményekre vonatkozik,amely egy nanométer vagy mikrométer méretű szilárd részecskékformájában jelen levő, vízben nem oldódó vegyületet tartalmaz, arészecskék felülete egy vagy több felületmódosítóval vanstablilizálva, és a felületmódosítók közül legalább egy foszfolipidlehet, a szilárd részecskék egy adott esetben felszabadítószert ismagában foglaló térfogatnövelő mátrix révén vannak diszpergálva, amelymegszárítva terápiás dózisformát alkot, és amikor ez a dózisformavizes közegbe kerül, a térfogatnövelő/felszabadító mátrix 2 percnélrövidebb idő alatt lényegében teljesen szétesik, ezáltal felszabadítjaa vízben nem oldódó szilárd anyag részecskéit nem aggregált és/vagynem agglomerált állapotban. Ó
Patent HU-0200721-A2 (HU)
Title: C10 carbamoyloxy substituted taxanes as antitumor agents and pharmaceutical compositions containing them and their use
Inventor: FANG WEISHUO
IPC: C07D407/12
Filed: 2001-02-02
Abstract: Compositions comprising a taxane having a carbamoyloxy substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents.