baber/WOPTO huggingface dataset:
Patent JP-H0634721-B2 (JP)
IPC: C12N9/50
Filed: 1984-03-23
Abstract: The invention provides a new class of DNA vectors, each comprising two replication systems; a first origin of replication resulting in a low copy number and stable inheritance of the plasmid, and a second, high copy number, origin of replication at which replication is directly controllable such that, when host cells carrying the vector are propagated under a first set of conditions, replication takes place mainly from the low copy number origin, and that when said cells are propagated under a second set of conditions, replication takes place also from the high copy number origin to produce a high yield of gene product. The controllable origin of replication may be under the control of a natural promoter of RNA transcription or a substitute promoter such as the PL promoter or lac promoter.
Patent JP-H0816117-B2 (JP)
IPC: C07J3/00
Filed: 1986-06-24
Abstract: 9 alpha, 11 beta and 11 beta-substituted estranes are disclosed which exhibit elevated estrogenic and postcoital contraceptive activities. A process for their manufacture and their use in pharmaceuticals is also disclosed.
Patent JP-3172181-B2 (JP)
IPC: A61K35/74
Filed: 1992-01-28
Granted: 2001-06-04
Abstract: A method of establishing direct feed microorganisms such as Lactobacillus reuteri in the gastrointestinal tract of avian organisms in which eggs are inoculated with living cells of the microorganism.
Patent JP-3053873-B2 (JP)
IPC: A61K47/48
Filed: 1995-08-11
Granted: 2000-06-19
Abstract: A chimeric LL2 monoclonal antibody is described in which the complementarity determining regions (CDRs) of the light and heavy chains of the murine LL2 anti-B-lymphoma, anti-leukemia cell monoclonal antibody has been recombinantly joined to the human kappa and IgG<SUB>1 </SUB>constant region domains, respectively, which retains the immunospecificity and B-cell lymphoma and leukemia cell internalization capacity of the parental murine LL2 monoclonal antibody, and which has the potential of exhibiting reduced human anti-mouse antibody production activity. A humanized LL2 monoclonal antibody is described in which the CDRs of the light and heavy chains have been recombinantly joined to a framework sequence of human light and heavy chains variable regions, respectively, and subsequently linked to human kappa and IgG<SUB>1 </SUB>constant region domains, respectively, which retains the immunospecificity and B-lymphoma and leukemia cell internalization capacities of the parental murine and chimeric LL2 monoclonal antibodies, and which has the potential for exhibiting reduced human anti-mouse antibody production activity. Vectors for producing recombinant chimeric and humanized chimeric monoclonal antibodies are provided. Isolated DNAs encoding the amino acid sequences of the LL2 variable light and heavy chain and CDR framework regions are described. Conjugates of chimeric and humanized chimeric LL2 antibodies with cytotoxic agents or labels find use in therapy and diagnosis of B-cell lymphomas and leukemias.
Patent JP-2814747-B2 (JP)
IPC: H01P7/08
Filed: 1995-08-23
Granted: 1998-10-27
Abstract: In order to compensate for changes in the resonant frequency of the resonator arising from variations in the distance between the reference distance (dS) and an actual distance (dS+/- DELTA dS) in HF stripline resonators with a stripline (10) arranged at a reference distance (dS) from a metal conductor (11), the stripline (10) is curved. The curvature induces eddy currents in the conductor (11) which reduce the inductance of the HF stripline resonator. The shorter/longer the distance between the stripline and the metal conductor, the smaller/greater the inductance. As the shortening/lengthening of the distance between two conductors also increases/reduces the capacitance of the HF stripline, however, with the appropriate dimensions of the curved stripline, the two effects cancel each other out and the frequency of the HF stripline resonator is virtually stable with the aforementioned distance variations. The two effects cancel each other out and the frequency of the HF stripline resonator is virtually stable with the aforementioned distance variations.
Patent JP-H07101185-B2 (JP)
IPC: B61B13/04
Filed: 1992-05-07
Abstract: A rail section (2) longer than the wheelbase of a conveyor carriage is hingedly connected to on one side (8) to a fixed carrier device (12). The other side (22) can move freely and is supported on a spring device (27) having an indicating and/or switching device (48). It is thus possible to prevent an overloaded conveyor carriage from running and hence to prevent damage to or breakdowns in a small conveyor installation.
Patent JP-2933283-B2 (JP)
IPC: C10M163/00
Filed: 1989-09-08
Granted: 1999-08-09
Abstract: Long-chain aliphatic hydrocarbyl polyamino additives which comprise a long-chain aliphatic hydrocarbyl moiety, a polyamino moiety and an oxy-carbonyl connecting group which joins the aliphatic hydrocarbyl moiety and the polyamino moiety are useful as dispersants in fuel compositions and in lubricating oil compositions.
Patent JP-4046195-B2 (JP)
IPC: A61M25/00
Filed: 1994-10-06
Granted: 2008-02-13
Abstract: A method for providing a synthetic barrier made of biocompatible polymeric materials  in vivo  which involves application of a material to a tissue or cellular surface such as the interior surface of a blood vessel, tissue lumen or other hollow space, is disclosed herein. The material may also be applied to tissue contacting surfaces of implantable medical devices. The polymeric materials are characterized by a fluent state which allows application to and, preferably adhesion to, tissue lumen surfaces, which can be increased or altered to a second less fluent state  in situ;  controlled permeability and degradability; and, in the preferred embodiments, incorporation of bioactive materials for release  in vivo , either to the tissue lumen surface or to the interior of the lumen, which alter cell-to-cell interactions. It has also been discovered that tenascin is a mediator of smooth muscle cell migration through interaction with specific integrin components of the cells.
Patent JP-3341058-B2 (JP)
IPC: A61F2/14
Filed: 1993-01-07
Granted: 2002-11-05
Abstract: A method for refractive correction of the eye in order to improve the vision of the eye while not adversely affecting its natural asphericity is described. The method involves determining the amount of correction necessary, selecting an intrastromal corneal ring (ICR) of appropriate thickness to obtain the necessary correction from a selection of ICRs of varying thickness, and inserting the ICR into the corneal stroma. The method may be useful for the correction of myopia and excessive astigmatism.
Patent JP-4241926-B2 (JP)
IPC: A61K31/138
Filed: 1996-10-10
Granted: 2009-03-18
Abstract: Compounds of formula (Ia) as potent, beta<SUB>1</SUB>-specific beta blockers with a short duration of action in the systemic circulation, wherein R is 3',4'-dimethoxyphenyl, R<SUP>1 </SUP>is hydrogen, and R<SUP>2 </SUP>is selected from methyl, ethyl, propyl, isobutyl and isopropyl; or R is 3',4'-dimethoxyphenyl, R<SUP>1 </SUP>is selected from fluorine, chlorine and bromine, and R<SUP>2 </SUP>is selected from methyl, ethyl, propyl, isopropyl, isobutyl and cyclopropylmethyl; of R is 4'-methoxyphenoxy, R<SUP>1 </SUP>is selected from hydrogen, fluorine, chlorine and bromine, and R<SUP>2 </SUP>is selected from methyl, ethyl, propyl, isopropyl, isobutyl and cyclopropylmethyl; or R is 3',4'-dimethoxyphenyl, R<SUB>1 </SUB>is cyano, and R<SUP>2 </SUP>is cyclopropylmethyl; or R is 4'-methoxyphenoxy, R<SUP>1 </SUP>is cyano, and R<SUP>2 </SUP>is isobutyl; and physiologically acceptable hydrolysable derivatives thereof having the hydroxy group in the 2-position of the 3-aminopropoxy side chain in esterified form, in their racemic and optically active forms, and their pharmaceutically acceptable acid addition salts.
Patent JP-3478396-B2 (JP)
IPC: C12N15/00
Filed: 1993-03-04
Granted: 2003-12-15
Abstract: The invention discloses the application of genetic engineering techniques to create novel strains of A. niger which produce high levels of catalase catR gene product, catalase-R) while generating minimal sodium gluconate waste material. Use of an Aspergillus glucoamylase promoter gene.
Patent JP-3585923-B2 (JP)
IPC: F16H61/02
Filed: 1994-02-17
Granted: 2004-11-10
Abstract: The transmission device (1b) comprises an epicycloidal train (7) with a crown connected to the input (2ab) and a planetary wheel (9) prevented from turning in a reverse direction by an idler wheel (16). A satellite carrier (13) is connected to the output shaft (2bc). A crown (8) and the satellite carrier (13) may be coupled by means of a clutch (18b) actuated for engagement by means of fly-weights (29) and a spring (34) to achieve a direct drive. If the engagement is sufficient for the torque to be transmitted, the planetary wheel (9) has its speed reduced and is finally immobilized by means of the idler wheel (16). The device operates then as a reduction unit, and an axial thrust (Pac) due to helical teeth occurs and disengages the clutch. It is also possible to operate the device as a reduction unit by means of a piston (44) which pushes the race (20) in the direction of disengagement of the clutch (18b) and applies a brake (43) which prevents any rotation of the planetary wheel (9), even in the direction normally permitted by the idler wheel (16). Utilization for the selective operation of the transmission device as a reduction unit when the vehicle engine operates in a retaining mode.
Patent JP-4005631-B2 (JP)
IPC: G06F12/00
Filed: 1996-01-23
Granted: 2007-11-07
Abstract: A network computer system providing for the fault tolerant storage and retrieval of data files includes a client system connected to a data communication network that may source a first data transfer request to said data communication network for the transfer or retrieval of data. A first server system, including first medium for storing data files, is connected to the data communication network so as to be responsive to first data transfer requests. A second server system, including second medium for storing data files is also connected to said data communication network to also be responsive to first data transfer requests. A control protocol, established between the first and second server systems, coordinates an asymmetric response by the first and second server systems to a first data transfer request, such that file data transferred by the client with the first data transfer request is replicated to the first and second storing mediums and such that file data transferred to the client system in response to the first data transfer is non-replicatively provided to the client system by either the first or second server system.
Patent JP-2834584-B2 (JP)
IPC: G06K19/077
Filed: 1996-02-29
Granted: 1998-12-09
Abstract: A data substrate with a semiconductor chip (1) connected to a first conductor loop (2) having at least one turn, with a second conductor loop (3) having at least one turn, the cross sectional area of which has approximately the dimensions of the data substrate, in which the cross sectional area of the first conductor loop (2) has approximately the dimensions of the semiconductor chip (1) and the two conductor loops (2, 3) are inductively interconnected.
Patent JP-4236701-B2 (JP)
IPC: B29C/
Filed: 1998-02-25
Granted: 2009-03-11
Abstract: A method of constructing a polymer support frame (10) over which woven wire cloth (158,159) is to be stretched and secured to form a sifting screen is described. The method comprises the steps of locating a reinforcing wire frame assembly in a mould tool. The wire frame comprises two parallel spaced apart arrays of reinforcing wires (48,50,54,56,60,62,64). After closing the mould, liquid polymer is injected into the mould tool so as to wholly encapsulate the wire frame and to form an article having an open central region criss-crossed by intersecting orthogonal ribs (14,16) bounded on all sides by a rigid flange. Each of the ribs (14,16) contains two of the parallel spaced apart wires of the frame assembly. After permitting the polymer to cure, the tool is opened and the article is removed. The wire frame assembly is located and held in shape and position by applying an inward force on opposite faces of the wire frame assembly within the mould tool, by fingers protruding inwardly from inside faces of the tool. The fingers engage the wire matrices when the tool closes. The polymer is typically a glass-reinforced plastics material, and in order to assist in bonding the wire cloth to the support frame (10) the faces of peripheral edge regions of the support frame (10) over which woven cloth (158,159) is laid and to which the cloth (158,159) is to be bonded by heating, are formed during moulding with a plurality of substantially parallel ridges (30,32).
Patent JP-4191259-B2 (JP)
IPC: C07K7/23
Filed: 1998-04-13
Granted: 2008-12-03
Abstract: Peptides are provided which have improved duration of GnRH antagonistic properties and/or which can be synthesized more economically. These antagonists may be used in the same manner as the compounds of which they are analogs to regulate fertility and to treat steroid-dependent tumors and for other short-term and long-term treatment indications. One particularly effective peptide, a decapeptide analog of the GnRH antagonist Acyline, has the formula: Ac-D-2Nal-D-4Cpa-D-Dpr(methylcarbamoyl)-Ser-4Aph(acetyl)-D-4Aph(acetyl)-Leu-Lys(isopropyl)-Pro-D-Ala-NH2. It continues to exhibit very substantial suppression of LH secretion at 96 hours following injection. Other economically attractive and pharmacologically effective analogs have the formulas: Ac-D-2Nal-D-4Cpa-Xaa3-Ser-4Aph(acetyl)-D-4Aph(acetyl)-Leu-Lys(isopropyl)-Pro-D-Ala-NH2; and Ac-D-2Nal-D-4Cpa-Xaa3-Ser-4Aph(hydroorotyl)-D-4Aph(acetyl)-Leu-Lys(isopropyl)-Pro-D-Ala-NH2, wherein Xaa3 is D-Gln or Gln.
Patent PL-158434-B2 (PL)
Title: Steering gear combined with road wheel drive for a composting machine
IPC: A01G1/04
Filed: 1988-10-06
Abstract: 1. Steering system with the working and manoeuvring drive of a composting machine characterized in that it has a manoeuvre engine (7) that propels twin wheels (13) by means of a gear (8), reducer (9), left and right steering system (10), left and right reducer (11), left and right gear (12), and the engine (14) for working drive that propels twin wheels (13) by means of the gear (15), reducer (16), clutch (17), reducer (9), left and right steering system (10), left and right reducer (11), and left and right gear (12).<IMAGE>
Patent ES-2341158-B2 (ES)
Title: Utensilio destinado para sujetar un animal comestible (sin vida) paraproceder a su pelado.
Inventor: MOLINA LINARES HELIODORO
IPC: A22B5/16
Filed: 2008-03-06
Granted: 2011-01-25
Abstract: Utensilio destinado para sujetar un animal
comestible (sin vida) para proceder a su pelado. 
     El dispositivo objeto de la invención: consta de
una base (1), un mástil (4), una hélice (2), una bisagra (8), una
cadena (7), dos correas (12), dos hembrillas (10), dos aros (13),
cuatro remaches (11), un pasador (6), tres tornillos (3) y (5), una
arandela (14) y un rodamiento de fijación (9). 
     La invención facilita la sujeción de un animal
comestible (sin vida) y su pelado, sin ayuda de otra persona.
Patent ES-2376858-B2 (ES)
Title: Dispositivo de fijación temporal y no reutilizable de al menos dos piezas una con otra con ajuste preciso de la fuerza de sujeción aplicada a las piezas.
Inventor: CORCHERO JUANA
IPC: F16B5/00
Filed: 2009-12-28
Granted: 2013-03-25
Abstract: La invención corresponde a un dispositivo de fijación (1) temporal y no reutilizable de al menos dos piezas una con otra con ajuste preciso de la fuerza de sujeción aplicada a las piezas.#Este dispositivo de fijación incluye un elemento deslizante (5) en un cuerpo alargado (4), el elemento (5) y el cuerpo alargado (4) tienen respectivamente costados y lienzos enfrentadas, cada costado del elemento (5) tiene un gancho (9, 9?, 9??, 9???) con al menos un diente (9a, 9b, 9c, 9?a, 9?c) y cada lienzo del cuerpo alargado (4) tiene una hilera (7, 7a, 7b) de estrías en las cuales (10, 10a, 10b) una es penetrada por un diente del gancho (9, 9?, 9??, 9???) que tiene al frente. Entre los costados adyacentes del elemento (5) o los lienzos del cuerpo alargado (4), existe entre las hileras (7, 7a, 7b) de estrías o ganchos (9, 9?, 9??, 9???) llevados por estos costados o lienzos, un desfase en la longitud igual a una porción de la separación entre dos estrías (10, 10a, 10b) consecutivas de una hilera (7, 7a, 7b), mientras que no hay desfase en la longitud entre hileras (7, 7a, 7b) de estrías o ganchos (9, 9?, 9??, 9???) respectivamente de lienzos opuestos del cuerpo alargado o de costados opuestos del hueco (5a).#Aplicación en todo campo técnico donde se necesita una fijación de al menos dos piezas una con otra.
Patent ES-2531010-B2 (ES)
Title: Método de recuperación y enriquecimiento de uranio mediante bioacumulación en microalgas mejoradas genéticamente
Inventor: COSTAS COSTAS EDUARDO
IPC: G21F9/18
Filed: 2012-12-04
Granted: 2015-07-16
Abstract: La presente invención se refiere a un método de recuperación de U y un método de enriquecimiento de U mediante bioacumulación en microalgas mejoradas genéticamente. Para obtener estas microalgas mejoradas, la invención incluye un método de mejora genética por selección artificial mediante el cual se ha obtenido la cepa Chlaf SCEP de Chlamydomonas fonticola. Esta cepa concentra en su interior, mediante bioacumulación activa, el uranio captado del exterior, en forma de precipitados metálicos que representan el 3% de la biomasa seca del alga. Además, produce un fraccionamiento isotópico de **IMAGEN** que puede aplicarse en sucesivos pasos para aumentar el enriquecimiento en 235U. La invención también incluye el uso de estas microalgas en la recuperación de uranio disuelto produciendo un fraccionamiento isotópico que puede utilizarse para conseguir uranio enriquecido de uso industrial, así como en su utilización en bio-remediación de aguas y/o suelos contaminados con uranio (en minería, depósitos de residuos radioactivos, piscinas de apagamiento -radioactive decay-, accidentes nucleares, vertidos, etc.).
Patent ES-2622469-B2 (ES)
Title: Procedimiento para el traslado de contenedores estandarizados entre un buque portacontenedores y un muelle
Inventor: RUIZ VEGA ANTONIO MARCOS
IPC: B66C17/20
Filed: 2016-01-06
Granted: 2018-03-08
Abstract: Procedimiento para el traslado de contenedores estandarizados entre un buque portacontenedores y un muelle, mediante utilización de grúas portuarias tipo pórtico, caracterizado porque en toda la maniobra los contenedores permanecen con sus ejes longitudinales perpendiculares al cantil del muelle.#Para llevar a cabo este procedimiento son necesarias dos invenciones estrechamente relacionadas con él: un buque portacontenedores con los contenedores estandarizados dispuestos con sus ejes longitudinales ortogonales al eje longitudinal del buque y una grúa portuaria tipo pórtico capacitada para trasladar contenedores estandarizados en una posición tal que sus ejes longitudinales sean ortogonales al cantil del muelle; esto permite que la separación entre sus patas sea menor que la de las grúas actuales pues dicha separación depende de la disposición del contenedor al pasar entre ellas; se consigue un mayor número de grúas operando en un mismo buque a igualdad de eslora, mejorándose los rendimientos de carga/descarga.
Patent AU-2001233875-B2 (AU)
Title: Fluid velocity transducer
Inventor: BISHOP WILFRED IGNATIUS
IPC: G01P5/14
Filed: 2001-02-15
Granted: 2006-04-27
Abstract: A transducer for measuring the relative velocity of movement of a body in a liquid or gaseous medium employs no reciprocating parts and functions by sensing the force applied to a diaphragm (6) die to its movement through the medium or the movement of the medium towards the diaphragm. The speed transducer makes use of a Hall effect solid state device (7) that produces an output when a magnetic field is applied to either of its surfaces. The level of the output voltage is proportional to the velocity of movement in the positive direction, i.e. when the force acts on diaphragm (6) in (FIG. 1). Since the transducer takes into account differential forces, an unwanted common force acting on both diaphragms simultaneously will have no effect on the measured speed. The tubular body (1) in which the Hall effect device is located may be made from any non-magnetic material suitable for the environment in which the transducer will be used.
Patent AU-2002213920-B2 (AU)
Title: New herbicidial compositions
Inventor: SLATER ASHLEY
IPC: A01N41/10
Filed: 2001-09-17
Granted: 2006-12-21
Abstract: A method for controlling the growth of weeds at a locus which comprises applying to the locus an effective amount of: (a) a urea herbicide of general formula (1); and (b) 2-(2'-nitro-4'-methylsulfonylbenzoyl)-1,3-cyclohexanedione or an agriculturally acceptable salt or metal complex thereof.
Patent AU-2002217464-B2 (AU)
Title: Medicinal compositions containing aspirin
Inventor: ASAI FUMITOSHI
IPC: A61K31/4365
Filed: 2001-12-20
Granted: 2004-12-16
Abstract: Pharmaceutical compositions comprising 2-acetoxy-5-( alpha -cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothienoÄ3,2-cÜpyridine or a pharmaceutically acceptable salt thereof, and aspirin, as active ingredients. ÄEffectÜ <??>The pharmaceutical compositions of the present invention possess excellent inhibitory activity against platelet aggregation and thrombogenesis, and are useful for preventing or treating diseases caused by thrombus or embolus.
Patent AU-2002219963-B2 (AU)
Title: High pressure low volume pump
Inventor: TALHOUET PHILIPPE DE
IPC: F04B53/14
Filed: 2001-11-30
Granted: 2007-01-04
Abstract: A piston carrier (46) supports an elongated, slender piston rod (12) for reciprocation in a pump cylinder (30) to pump fluid into and out of the cylinder (30). The piston rod (12) is made of a material such as sapphire or zircon and has a diameter less than about ten millimeters, and the pump (10) can provide flows of from about 50 to about 250 microliters per minute at pressures of several hundred bars. A drive motor (18) rotates a threaded screw (58) and a drive nut (70) of a drive system (26) applies a linear drive force to the piston carrier(46). A ball and socket connection (74) between the drive system (26) and the piston carrier (46) avoids the need for precise alignment to prevent breakage of the fragile piston (12). A magnet (80) in the socket (78) holds the ball (76) in place and avoids the need for a spring or other mechanical holder. The socket (78) also includes a ring (88) of a low reluctance material surrounding the ball (76) to increase the magnetic retention force. <IMAGE>
Patent AU-2002350797-B2 (AU)
Title: Method for estimation of the amount of specific cell types
Inventor: VENGE PER
IPC: G01N33/569
Filed: 2002-06-24
Granted: 2008-03-20
Abstract: The present invention relates to the estimation of the amount of subtypes of specific cells, for example the number of certain subtypes of leukocytes, by measurements of unique proteins in extracts of blood and other biological material. The knowledge of the number or amount of specific subtypes of white cells is important in the clinical diagnosis and surveillance of subjects with inflammatory disease including infectious disease, cancer, allergy/asthma etc.
Patent AU-2002351238-B2 (AU)
Title: Cultured cells from pancreatic islets
Inventor: JIN JIANJIAN
IPC: A61K35/12
Filed: 2002-12-04
Granted: 2009-01-08
Abstract: A cell composition of endocrine progenitor cells derived from mammalian pancreatic islet cells that can be trans-planted planted into a diabetic patient such t the cells of the cell composition differentiates into functioning insulin-producing beta cells.