baber/WOPTO huggingface dataset:
Patent DE-69624824-T2 (DE)
Inventor: ROMAGNANI SERGIO
IPC: A01N63/00
Filed: 1996-07-19
Granted: 2003-09-11
Abstract: The lymphocyte ativation gene (LAG-3) is a member of the immunoglobulin superfamily that is selectively transcribed in human activated T and NK cells. Surface LAG-3 expression correlated with IFN-gamma but not IL-4, production in antigen-stimulated T-cells and it was up-regulated by IL-12 and is preferentially associated with CD4+ T-cells producing Th1-type cytokines. The presence of LAG-3 on the surface of Th1 lymphocytes is used as a marker to detect and identify Th1 lymphocytes and differentiate them from Th2 lymphocytes. Monoclonal antibodies to LAG-3 are used in methods of detecting and isolating Th1 cells as well as methods of diagnosing Th1-mediated disease. The present invention also relates to methods of treating infectious diseases, cancer, and disorders assocated with Th1/Th2 imbalance.
Patent DE-69629938-T2 (DE)
Inventor: STUDHOLME M
IPC: G01N33/80
Filed: 1996-11-18
Granted: 2004-07-15
Abstract: Whole blood is mixed with a reticulocyte reagent system that has a reticulocyte staining reagent and a diluent reagent, used in combination. This mixture is incubated at room temperature for between about 15 minutes to about 4 hours. The incubated mixture is then analyzed and the light scattering properties of the cells are detected, collected, differentiated and quantitized. Data gathering includes, at least, 10 and 90 degree light scatter detection.
Patent DE-69635924-T2 (DE)
Inventor: MATHER P
IPC: A61K35/30
Filed: 1996-04-26
Granted: 2006-12-14
Abstract: A method for enhancing the survival and/or proliferation of Schwann cells (especially human Schwann cells) in cell culture is disclosed which involves culturing the cells in serum free culture medium comprising gas6 and other mitogenic agents, such as heregulin and forskolin. The culturing step is generally preceded by a pre-incubation period wherein nerve tissue comprising the Schwann cells is cultured under appropriate conditions and for a period of time such that demyelination occurs. The isolated Schwann cells can be used as cellular prostheses to treat patients with nervous system injuries. The invention also provides a cell culture medium for culturing Schwann cells.
Patent DE-69636619-T2 (DE)
Inventor: PANTICH VLADIMIR
IPC: C10M175/02
Filed: 1996-05-30
Granted: 2007-08-30
Abstract: The invention relates to separating different substances, more concretely, to a method and apparatus for filtering, degassing, dehydrating and removing products of ageing in insulating and other petroleum oils. The technical result is that the aforesaid phases of processing oil or a mixture of oils are ensured with high efficiency for a single passage through an active component, and also the possibility of regenerating the adsorbents being used is ensured during the process of operation of the equipment, with simultaneous simplification of the construction and reduction of size and of power consumption. The apparatus 1 for filtering, degassing, dehydrating and removing products of ageing comprises at least one tank 2, in which are disposed cylindrical partitions 3, 4 filled with an adsorbent 5 and secured in the tank 2 by means of fixing elements 6. Partitions 3, 4 form channels for the passage of oil being processed. The tank 2 has an inlet opening 7 and an outlet opening 8, with mechanical filters 9, 10 mounted in the openings. An electric drive 12, connected to a delivery pump 13, is mounted on a base 11 of the apparatus 1. Equipment 14 for protecting and starting the electric drive 12 is also arranged on the base 11. Circulation pipe-lines 15 interconnect separate parts of the apparatus 1, and also connect separate apparatuses 1 in the composition of installations for processing oils to each other and to a user's tanks with the oil being processed. <IMAGE>
Patent DE-69705801-T2 (DE)
Inventor: HOLMSTROEM MATS
IPC: G01N33/38
Filed: 1997-10-21
Granted: 2001-12-06
Abstract: The present invention relates to a process for protecting and cleaning surfaces of material members, which are exposed to the damaging action of water-soluble salts present therein. More specifically, the process comprises the assessment of the saturation vapour content of salt or salts present in the surface layer of the material, the provision of a buffer zone between the surface layer and the environment, the climate in the buffer zone being insulated from the environment, and the regulation of the climate in the buffer zone on the basis of the assessed saturation vapour content. The invention also relates to a method for determining the saturation vapour content of salt present in a material surface, which method is particularly usable for determining saturation vapour contents in the above-mentioned process according to the invention.
Patent DE-69708443-T2 (DE)
Inventor: TAZAKI HIROSHI
IPC: C08K5/20
Filed: 1997-08-01
Granted: 2002-05-16
Abstract: A dispersion composition suitable for a magnetic display comprises 10 to 30 wt% of magnetic particles having a particle diameter of 10 to 150  mu m, 0.01 to 0.5 wt% of an antistatic agent, 1 to 10% by weight of an organic thickening agent, 0.1 to 10% by weight of a colorant and a balance of an organic dispersing medium.
Patent DE-69709475-T2 (DE)
Inventor: KIISKINEN ESKO
IPC: H02H3/08
Filed: 1997-02-20
Granted: 2002-09-19
Abstract: The present invention relates to protection circuit and method for the EMI/RFI suppression system (2) of such a five-conductor electrical system in which the neutral conductor (N) is provided with a bandstoptype filter circuit (2) for the suppression of a harmonic interference current component. According to the invention, on the neutral conductor (N) is placed a current transformer (CT) having over its secondary a resistive branch (R1), and in parallel therewith, a filter branch (5) comprising a bandpass filter (LC) tuned to the fundamental frequency of said neutral-conductor filter circuit (2) and said filter branch (5) having in series with said bandpass filter branch (LC) a switch element (4) suitable for short-circuiting said neutral-conductor filter circuit (2) when current in said filter branch (5) exceeds a preset upper limit level.   <IMAGE>
Patent DE-69716612-T2 (DE)
Inventor: GRUNDITZ LEIF
IPC: B02C23/14
Filed: 1997-08-05
Granted: 2003-07-10
Abstract: A method for treating wastes, such as domestic wastes, industrial wastes and similar, the wastes passing several treatment steps and being thereafter separated in various fractions, <u>characterized in</u> that it consists of at least the following steps: a coarse crossing of the received waste materials; a heavy rejects separation of the waste materials in an aqueous phase and a removal of the rejects for further treatments; a grinding of the accepts from the heavy rejects separation and a transport of the ground materials and the fluid to a pulper; a dissolving of these materials in the pulper with a simultaneous, at least periodic grinding; a separation of the suspension completely treated in the pulper into various fractions; and a transport and a further treatment of the created fractions. The invention also relates to a device for performing the method. By means of the invention, a more effective handling of wastes is achieved and also, a large portion of heavy components are early removed from the process and a hawser-like formation is avoided of string-like components.
Patent DE-69719095-T2 (DE)
Inventor: PALMIERI BENIAMINO
IPC: A61P43/00
Filed: 1997-10-09
Granted: 2003-07-24
Abstract: Bile acid metal salts of therapeutic interest and pharmaceutical and veterinary composition containing same for the treatment of anemias and other conditions are described.
Patent DE-69728911-T2 (DE)
Inventor: ERIKSSON JAN-OLOF
IPC: C02F1/50
Filed: 1997-02-13
Granted: 2005-04-28
Abstract: PCT No. PCT/SE97/00224 Sec. 371 Date Sep. 2, 1998 Sec. 102(e) Date Sep. 2, 1998 PCT Filed Feb. 13, 1997 PCT Pub. No. WO97/30589 PCT Pub. Date Aug. 28, 1997A method for the control of microorganisms, especially spore forming organisms, algae, yeast fungi and slime bacteria by bringing an active amount of sodium percarbonate and/or sodium peroxide into contact with the microorganisms.
Patent DE-69732370-T2 (DE)
Inventor: WOULFE R
IPC: A61K49/00
Filed: 1997-11-12
Granted: 2005-09-15
Abstract: The present invention provides compositions comprising contrast agents capable of binding non-covalently to blood proteins. The compositions of the invention provide increased residence time of contrast agents in the vasculature, thus providing effective blood pool contrast agents. The invention also provides methods for imaging a patient comprising administering a composition of the invention to a patient and obtaining an image.
Patent DE-69734661-T2 (DE)
Inventor: RAMAMURTHY S
IPC: A61P17/02
Filed: 1997-08-01
Granted: 2006-08-10
Abstract: A method for improving the healing response of epithelialized tissue (e.g., skin, mucosae) to acute traumatic injury is disclosed. The method includes employing a tetracycline compound, having substantially no antibacterial activity, to improve the capacity of the epithelialized tissue to heal acute wounds. Specifically, the method involves increasing the rate of collagen accumulation of the healing epithelialized tissue above that associated with wound healing in the individual. The method decreases proteolytic activity in the epithelialized tissue by means of the tetracycline compound, most commonly decreasing collagenolytic activity and/or decreasing gelatinolytic activity. Collagenase and gelatinase activity have been shown to be decreased by the method of the invention. Preferably, the method is employed to improve the wound healing capacity of human or animal subjects in whom such capacity is impaired. Also, the non-antibiotic tetracycline is preferably administered topically at the site of the wound.
Patent DE-69735885-T2 (DE)
Inventor: ZHANG YING
IPC: A61K38/00
Filed: 1997-05-23
Granted: 2006-11-30
Abstract: Disclosed are methods, probes, primers and kits for identifying pyrazinamide-resistant mycobacteria. These methods can be used to distinguish M. bovis from M. tuberculosis, as well as to identify additional pyrazinamide-resistant mycobacteria. Also disclosed are methods for treating mycobacterial infections by expressing a pncA gene in mycobacteria that infect a mammal, and treating the mammal with pyrazinamide. The invention derives from the discovery of that the molecular basis for pyrazinamide resistance is an alteration in the pncA gene of mycobacteria. The detection of such an alteration is an indicator of PZA-resistant mycobacteria.
Patent DE-69805537-T2 (DE)
Inventor: SOPER C
IPC: B01J13/10
Filed: 1998-10-05
Granted: 2002-12-05
Abstract: A method of encapsulating an amphiphilic flavor or fragrance compound into a microcapsule having a hydrogel shell and an oil core. The flavor or fragrance compound is transported into and solubilized in the core by partition coefficient equilibrium using water in the capsule wall to transport the compound into the core. Microcapsules made by the method of the invention may have a wall thickness and contain a high concentration of the flavor or fragrance compound that has not previously been feasible.
Patent DE-69806259-T2 (DE)
Inventor: STEWART TIMOTHY NATHANIEL
IPC: A46B11/06
Filed: 1998-09-16
Granted: 2003-02-27
Abstract: A toothbrush including a handle that has a first chamber towards a closed end in which is located a bristled head, and access passageways through the bristled head externally of the bristles. The access passageways communicate with the first chamber. A fluid supply line is provided on or in the side of the first chamber from which extend the bristles of the bristled head. The fluid supply line extends into the bristled head and has at least one outlet sited within the confines of the bristles. In addition, there is an air vent to prevent a build up of vacuum in the mouth of the user, located on the side of the first chamber from which extend the bristles of the bristled head. The air vent terminates at one end in close proximity to the bristles to that side of the bristled head, and terminates at the other end at a distance along the length of the handle to ensure that it cannot be fouled by the mouth of a user.
Patent DE-69808372-T2 (DE)
Inventor: YAMAKADO YOSHIHIKO
IPC: C08G77/442
Filed: 1998-05-26
Granted: 2003-09-04
Abstract: A process is disclosed for producing a shading spacer suitable for use in a liquid crystal, which comprises:   (a) forming a slurry of cross-linkable polymer particles by the deposition-polymerization of a monomer mixture which comprises vinyl monomers having a hydrolysable silyl group; (b) adding to the polymer particles, simultaneously or sequentially in either order, a cross-linking catalyst and a dyestuff which contains a hydrolysable silyl group; and (c) recovering the resulting dyed cross-linked polymer particles.
Patent DE-69808427-T2 (DE)
Inventor: NINANE LEON
IPC: B09B1/00
Filed: 1998-01-14
Granted: 2003-06-18
Abstract: The invention concerns a method for refuse piling for dumping of solid residue containing heavy metals, which consists in setting in the dump (1), above the solid residue (5), a layer (4) of alkaline-earth metal carbonate.
Patent DE-69814683-T2 (DE)
Inventor: BADYAL PAL
IPC: C08J5/12
Filed: 1998-12-18
Granted: 2004-02-26
Abstract: A thin fluoropolymer film is bonded to a substrate for medical, filtration or packaging purposes by using a pulsed or combination of gas and electrical pulsed cold plasma polymerization procedures.
Patent DE-69819475-T2 (DE)
Inventor: BARBER TED
IPC: A43B/
Filed: 1998-01-15
Granted: 2004-09-09
Abstract: PCT No. PCT/US98/00336 Sec. 371 Date Jul. 2, 1999 Sec. 102(e) Date Jul. 2, 1999 PCT Filed Jan. 15, 1998 PCT Pub. No. WO98/31247 PCT Pub. Date Jul. 23, 1998An ankle support assembly for use in combination with a soft-style snowboard boot. The assembly includes a rigid heel cup and a high back support for supporting the calf region of the snowboard rider. The high back support includes an extension member having a bottom end portion that is coupled within a pocket formed in the upper rear region of the heel cup. The coupling permits the high back support to float about a pivot axis that is translatable a predetermined amount along transverse, longitudinal and vertical axes of the ankle support assembly so as to enable articulation of said ankle support device in a manner that closely approximates the articulation of the foot and ankle of the snowboard rider. A tether is provided to prevent inadvertent decoupling of the high back support from the heel cup. Also included is a length adjustable tension cable to provide forward lean adjustment for the assembly.
Patent DE-69822976-T2 (DE)
Inventor: GOUX NICOLAS
IPC: A61M1/16
Filed: 1998-12-08
Granted: 2005-04-07
Abstract: The mass of urea in a fluid volume is calculated by performing mass exchange between the fluid volume and an exchange fluid flow. The concentration of the urea is repeatedly measured in the exchange fluid flow after the mass exchange to obtain a concentration curve. An approximation curve is fitted to at least a portion of the concentration curve. The logarithm of the approximation curve is a straight line whose slope is used to calculate the urea concentration.
Patent DE-69831807-T2 (DE)
Inventor: JEPSEN LUND
IPC: B03C3/78
Filed: 1998-06-29
Granted: 2006-07-20
Abstract: Filter plates in an electro-filter are cleaned using nozzles which, during spraying, are displaced longitudinally with the side edges of the filter plates while at the same time being rotated. The nozzles are mounted in a plane slightly different from the plane of the filter plates to enable the spray jets to reach the furthermost areas of the plates when the nozzles are at the greatest angle of incidence during washing.
Patent DE-69832167-T2 (DE)
Inventor: RAVKIN ILYA
IPC: G02B21/08
Filed: 1998-05-12
Granted: 2006-07-20
Abstract: Detection of fetal nucleated red blood cells (NRBCs) is achieved by employing a combination of brightfield and fluorescence images of nuclear and cytoplasmic markers. The brightfield and fluorescence images are all obtained with a single multi-bandpass dichroic mirror. The objects in the sample are stained with a fluorescent dye that selectively stains nuclei and a dye that selectively stains fetal hemoglobin in the cytoplasm of fetal RBCs. UV excitation provides fluorescent emissions from the stained cell nuclei and visible illumination provides brightfield transmission of light that is absorbed by the stained cytoplasm. The images are processed to determine regions where the fluorescent emissions by cell nuclei in response to the UV excitation and the absorption by fetal hemoglobin of the brightfield illumination overlap or are in close proximity. The brightfield and fluorescence images may be sequentially acquired or derived from a single image where the UV excitation and visible illumination occur simultaneously.
Patent DE-69905337-T2 (DE)
Inventor: GLYNN JERROLD SCOTT
IPC: H01R13/7195
Filed: 1999-11-25
Granted: 2004-01-22
Abstract: A filter electrical connector (10) having a housing (12) and a contact and filtering circuit subassembly (32). The contact and filtering circuit subassembly (32) has a ferrite block (25), electrical contacts (24) passing through the ferrite block (25), and a lead frame (30) and circuit element assembly (32). The lead frame (30) and circuit element assembly (32) is mounted on the ferrite block (25) and is electrically connected to the electrical contacts (10). <IMAGE>
Patent DE-69907006-T2 (DE)
Inventor: MANNER LEE
IPC: C09K21/14
Filed: 1999-09-29
Granted: 2004-04-29
Abstract: An absorbent and time release material formed from a dried pulp impregnated with an impregnating substance such as wax or oil, that is ground to a powder or pellet form. The material can be used to suppress fires, reclaim land, retain water, provide traction on slippery surfaces, and enhance or replace soil mixes.
Patent DE-69908385-T2 (DE)
Inventor: FORSTER HENRY
IPC: F21V8/00
Filed: 1999-09-01
Granted: 2003-12-18
Abstract: An edge-lit illumination system comprising a light transmitting sheet (10) and a light source (13, 14); the light source (13, 14) being positioned in proximity to and adjacent to an edge of said light transmitting sheet (10), characterised in that at least one of the two opposing surfaces (11, 12) of said light transmitting sheet (10) carries markings such that said markings are disposed randomly within each of at least one nominal area of said at least one surface. If this novel surface treatment is disturbed or disrupted, for example by staining or abrasion, the disruption to the illumination of the system is less than would be expected.
Patent DE-69917062-T2 (DE)
Inventor: HUSSON ALAIN
IPC: E02F3/36
Filed: 1999-10-21
Granted: 2005-04-28
Abstract: Quick fastener system for fixing a tool at the end of a loading arm. The system includes a first part coupled to the loading arm. The first part includes a cradle and a first aperture. A second part is arranged on the tool. The second part includes an element having a hook-shaped extension and a shaft which is adapted to be engaged by the cradle. A locking member is adapted to engage the hook-shaped extension. The tool is movable by the loading arm when the cradle engages the shaft and when the locking member engages the hook-shaped extension.
Patent DE-69919591-T2 (DE)
Inventor: LEANDERSSON ANDERS
IPC: D21F2/00
Filed: 1999-12-02
Granted: 2005-09-08
Abstract: A press in a wire part having a headbox (3) and a forming wire (4), which press has a first press member (13), arranged in the loop of the forming wire (4), a second press member (14), arranged outside the loop of the forming wire (4), which press members form at least one press nip, and an outer clothing (15), running in a loop outside the forming wire (4) to carry the web after the press nip to a press section. In accordance with the invention, the press has an inner belt (20), running in a loop inside the loop of the forming wire around the first press member and through the press nip and having water-receiving voids (22) that are open towards the forming wire. When the belt is the only water-receiving member, the voids of the belt constitute an open volume that is equal to or greater than the volume of water pressed out of the web in the press nip. Conditioning devices are located downstream of the press nip to remove the received water from the voids of the belt. The invention also relates to a wire part with at least one such press.
Patent DE-69926708-T2 (DE)
Inventor: BIGOTTO PIER CARLO
IPC: H01R13/629
Filed: 1999-11-25
Granted: 2006-06-22
Abstract: An electric connector (2) having an insulating casing (5) with a number of cavities for respective electric terminals (4); a slide (15) movable with respect to the casing (5) in a direction perpendicular to the connection direction (A) of the terminals (4), and in turn having cam means (20) interacting with a complementary connector (3) to generate a force for mating the connectors (2, 3) in response to translation of the slide (15); and an activating lever (24) connected in articulated manner to the slide (15) and to the casing (5) by means of pins (27, 36) which engage respective slots (29, 35) in sliding manner to impart a translatory component of motion to the lever (24), and to vary the resisting arm of the lever (24) during rotation of the lever (24). <IMAGE>
Patent DE-69928927-T2 (DE)
Inventor: MEHTA RAKESH
IPC: A61P1/10
Filed: 1999-06-03
Granted: 2006-08-17
Abstract: A spill-resistant pharmaceutical formulation for oral administration from a squeezable container comprises a pharmaceutical agent in a suitable vehicle comprising a liquid base and a thickening agent, the formulation consisting of mutually compatible components and having the following properties: a viscosity within the range of about 7,500 to about 12,500 cps using a Brookfield Viscometer with a "C" spindle with Helipath movement at a spindle speed of 10 rpm and 20-25 °C, a viscometric yield value of a semisolid, a spill-resistant consistency permitting the composition to be squeezed by light manual pressure through a channel, to spread in a spoon bowl sufficiently quickly for accurate measurement, and to remain in the spoon bowl without spilling on spoon inversion, tilting at 90 degrees, and vibration, homogeneity such that the components do not separate under conditions of use, and a storage stability such that the foregoing properties are retained for at least two years shelf life. A method for producing a formulation for a spill-resistant pharmaceutical composition comprises combining a per-unit dose effective amount of a pharmaceutical agent with suitable vehicle components comprising a liquid base and a thickening agent, and testing the formulation for acceptance criteria.