baber/WOPTO huggingface dataset:
Patent DE-69117957-T2 (DE)
Inventor: HOLMES ANDREW
IPC: H01L33/42
Filed: 1991-08-22
Granted: 1996-11-14
Abstract: A method is provided for forming in a semiconductive conjugated polymer at least first and second legions having different optical properties. The method comprises: forming a layer of a precursor polymer and permitting the first region to come into contact with a reactant, such as an acid, and heat while permitting the second region to come into contact with a lower concentration of the reactant. The reactant affects the conversion conditions of the precursor polymer in such a way as to control the optical properties of at least the first region so that the optical properties of the first region are different from those of the second region. The precursor polymer may comprise a poly(arylene-1, 2-ethanediyl) polymer, at least some of the ethane groups of which include a modifier group whose susceptibility to elimination is increased in the presence of the reactant.
Patent DE-69121452-T2 (DE)
Inventor: BREAKFIELD XANDRA O
IPC: A61P25/28
Filed: 1991-04-16
Granted: 1997-01-02
Abstract: Methods of gene delivery to cells in the central nervous system are disclosed by introducing and expressing gene sequences mediated by herpes simplex virus 1 (HSV-1) vectors with a mutation in a gene for viral replication. <IMAGE>
Patent DE-69204044-T2 (DE)
Inventor: GUZZINATI ALBERTO
IPC: E05B29/00
Filed: 1992-12-18
Granted: 1996-03-21
Abstract: A safety lock for house doors and the like, adapted to be operated by a key having a front active profile (3), comprises an outer drum member (4), a cylindrical body (9) rotatably mounted with respect to the drum member and arranged within the latter and a number of safety plates (29) having notches (29a), housed internally to a cavity (13) of the cylindrical body and pivotally mounted around a pin (30). A tab (27) prevents, when the lock is locked, the rotation of the cylindrical body (9) with respect to the drum member (4). By inserting the key in the keyhole, the safety plates reach a reciprocal position which is such that the notches (29a) define a seat which receives the tab (27) thereby unlocking the lock. A cam member (33), which is tiltalble around the pin (30) and is urged by a spring (24), brings the tab back in the locking position when the key is withdrawn. By the oscillating arrangement of the safety plates (29) and the cam member (33), a lock of reduced axial bulk is obtained. <IMAGE>
Patent DE-69220372-T2 (DE)
Inventor: MODERATHO BO
IPC: A47G1/14
Filed: 1992-08-27
Granted: 1998-01-15
Abstract: An object-supporting device, such as a device for supporting a flat signboard, a photograph frame or the like intended to be used in an upstanding position while supported by the support device, the device being intended to take a generally flat first position, transport and storage position, conforming to the configuration of the object, and a second position, a supporting position, in which part of the device extends from the object to form a support part which is intended to lie against an underlying surface. The object-supporting device is characterized by at least one flexible and resilient, generally sheet-like support part (3) which includes an attachment part (4) which is intended to be attached to the object (1) to be supported, and at least one tongue-like part (5) having a free-end (6) which preferably faces towards the attachment part (4) in a first position, wherein the free-part of the support-part is intended to be bent outwards away from the object (1) to place the device in the object-supporting position, and wherein the tongue-like part (5) is intended to be bent inwardly so that its free-end (6) abuts the object and therewith holds the support-part (3) in its outwardly bent position.
Patent DE-69221717-T2 (DE)
Inventor: ISHII MITOSHI
IPC: H01L21/677
Filed: 1992-11-30
Granted: 1998-01-15
Abstract: In ICs equipped with a lead frame, jigs for transferring, stocking and positioning in accordance with kinds are eliminated. ICs stacked and loaded into a cassette (4) are inserted into the center of a cassette space (35) and held. A moving table (9) is driven and moved by a servo motor (21). A push-up member (67) of an IC push-up mechanism (60) is pushed up by a distance corresponding to the thickness of one IC inside the cassette (4). A width registration device (70) centers the IC in both transverse and longitudinal directions, and positions them. <IMAGE>
Patent DE-69223755-T2 (DE)
Inventor: WESTERN LINDA M
IPC: C12Q1/70
Filed: 1992-10-09
Granted: 1998-04-23
Abstract: A method is disclosed for extending an extender probe to produce a single stranded polydeoxynucleotide that is free of unreacted extender probe and has two segments that are non-contiguous and complementary with each other. The method comprises the steps of (1) providing in combination (a) a polynucleotide having two non-contiguous, non-complementary nucleotide sequences S1 and S2 wherein S2 is 5' of S1 and is at least ten deoxynucleotides long, (b) an extender probe comprised of two deoxynucleotide sequences, wherein the sequence at the 3'-end of the extender probe (EP1) is hybridizable with S1 and the other of the deoxynucleotide sequences (EP2) is substantially identical to S2 and (c) means for modifying the 3'-end of extender probe that does not hybridize with the polynucleotide and (2) extending the extender probe along the polynucleotide wherein extender probe not hybridized to the polynucleotide becomes modified at its 3'-end. A method is also disclosed for forming a polynucleotide sequence complementary to a single stranded target polynucleotide sequence ("target sequence"). In the method a polynucleotide primer having a 3'-terminus comprised of a nucleotide monophosphate, which has at least one phosphate-sulfur bond, is hybridized to the 3'-end of the target sequence. The polynucleotide primer is extended along the target sequence and the extended polynucleotide primer is then dissociated from the target sequence. The method finds particular application in the area of nucleic acid amplification.
Patent DE-69300820-T2 (DE)
Inventor: WESTLAKE THEODORE
IPC: G01N30/30
Filed: 1993-02-18
Granted: 1996-06-13
Abstract: An apparatus broadly useful for analytical or for fluid separations purposes which is characterized by a grooved support member having a tubular membrane, optical fiber, capillary column or the like supported within the groove of such support member, and various analytical, process control or fluid separations apparatus incorporating the same.
Patent DE-69308147-T2 (DE)
Inventor: CATT MICHAEL BRAMPTON CLOSE
IPC: G01N33/493
Filed: 1993-08-10
Granted: 1997-06-19
Abstract: A method of monitoring the status of a current ovulation cycle of an individual human female subject, involving testing of the body fluid concentration of an analyte of significance in relation to the status of the ovulation cycle, such as urinary E3G, during at least part of the pre-ovulation phase of the current ovulation cycle of the individual subject, and identification from the results of such testing an analyte concentration change indicative of imminent ovulation, relative to an analyte concentration reference value that has been adapted to the individual human subject on the basis of analyte concentration test data obtained from the individual human subject during one or more previous ovulation cycles. Preferably testing for said analyte concentration during the current ovulation cycle is commenced a plurality of days (preferably at least 5) following the onset of menses but at least 2 numerical days in advance of the earliest numerical day on which actual ovulation has occurred in one or more previous ovulation cycles in the same individual subject.
Patent DE-69311559-T2 (DE)
Inventor: YANIGER STUART
IPC: G01L1/20
Filed: 1993-09-02
Granted: 1998-01-29
Abstract: A pressure transducer includes a base ply, a resistance ply disposed on the base ply and at least two spaced apart contacts juxtaposed in relation to the resistance ply whereby at least one of the contacts may be pressed against the surface of the resistance ply. The resistance ply is made by spraying or silk screening a mixture of resin resistive to electrical conduction and a conductive particulate and then curing the composition to form a thin resistance ply having a surface with a multiplicity of micro-protrusions formed by the conductive particulate. The ratio of conductive particulate to resin is such that the mean distance between microprotrusions is greater than about five time the size of the conductive particles. The particles are in the range of about 0.5 to 10 microns and the resin layer is about is 0.4 to 0.8 microns thick.
Patent DE-69314494-T2 (DE)
Inventor: HELLER SAMUEL
IPC: H02P9/48
Filed: 1993-07-26
Granted: 1998-04-23
Abstract: A rotary induction generator having a stator with stator windings (21) defining a three-phase stator and a rotor mounted for rotation therein and having wound thereon three rotor windings (22) defining a three-phase rotor and having resistive-reactive means (23, 24, 26) connected to said secondary windings (22) to increase the efficiency of said generator and limit the power output to the capacity of the generator over a wide range of speeds; and the method for load limiting electric power generation with rotary induction generators wherein the generator can run at variable speeds while maintaining the frequency of the line connected thereto over a wide range of prime mover speeds whereby the excess kilowatt output is limited by the circuit employing a first circuit of three sets of resistance, inductance and capacitance means (23, 24, 26) connected in series from each leg of a wye or delta configuration, and wherein each of said sets is connected in parallel with a separate set of resistors (27) to complete the circuit therein and assist in controlling the maximum point in kilowatts.
Patent DE-69319719-T2 (DE)
Inventor: STRAUS JAROSLAV
IPC: A61B18/04
Filed: 1993-03-22
Granted: 1999-06-10
Abstract: PCT No. PCT/CZ93/00004 Sec. 371 Date Sep. 22, 1994 Sec. 102(e) Date Sep. 22, 1994 PCT Filed Mar. 22, 1993 PCT Pub. No. WO93/18714 PCT Pub. Date Sep. 30, 1993A method of carrying out cryosurgical interventions includes cooling biological tissue at a rate of at least 180 K/min to a temperature of -190 DEG  C. to -160 DEG  C., subsequently rewarming the biological tissue at a rate of 100 to 240 K/min to a temperature of -70 DEG  C. to -20 DEG  C. with a subsequent rewarming at a rate of 10 to 25 K/min to a temperature of -5 DEG  C. to +5 DEG  C., and further rewarming the biological tissue up to body temperature. The total time of the controlled rewarming of the biological tissue is shorter than 5 minutes. An apparatus for carrying out the method of cryosurgical interventions includes a container of cooled medium an operating instrument, and a control unit for controlling the cooling and subsequent rewarming of biological tissue. The control unit includes a microprocessor coupled to electronic switches and a measuring unit.
Patent DE-69404437-T2 (DE)
Inventor: PEASE JACQUELINE K
IPC: C09K23/00
Filed: 1994-11-08
Granted: 1997-12-04
Abstract: Disclosed are concentrated high flash point surfactant compositions comprising an alcohol ethosulfate free of low flash solvents, a primary alcohol ethoxylate and glacial acetic acid in a weight ratio of 5 to 80% alcohol ethosulfate, 80 to 20% alcohol ethoxylate and 2 to 20% acetic acid. Preferably, a fourth component consisting of a nonionic surfactant such as caster oil ethoxylate is employed in the composition.
Patent DE-69406416-T2 (DE)
Inventor: HIRSCH MARK ANTHONY
IPC: F16D23/06
Filed: 1994-12-19
Granted: 1998-05-28
Abstract: A pin-type, double-acting synchronizer mechanism (18) with friction clutches (20,32 and 22,34), jaw clutches (24,14b and 26,16b) and a shift flange (28) which is rotatable relative to the shaft and jaw clutch members (24,26). Three circumferentially spaced pins (36) include blocker shoulders (36c,36d) for preventing asynchronous engagement of the jaw clutches, and pre-energizer surfaces (36e,36f) which each cooperate with a pre-energizer assembly (38). Friction members (20,22) of the friction clutches are slidably splined to gears to prevent relative rotation therebetween and abut surfaces (14d,16d) defined by gears (14,16) to limit axial movement away from mating friction rings (32,34), respectively. Axial movement toward the mating friction rings is limited by rigid pins (44) slidably extending through openings (32b,34b) in the rings. The mechanism (18) may have self energizing ramps acting between the shaft (12) and the jaw clutch members (24,26), flange (28) including radially inwardly extending teeth (48) defining self-energizing ramps (48a,48b,48c,48d) which act against ramps (50a,50b,50c,50d) defined by a post-like portion (50) formed from shaft splines (12b). <IMAGE>
Patent DE-69418059-T2 (DE)
Inventor: SINDZINGRE THIERRY
IPC: C23C16/42
Filed: 1994-12-07
Granted: 1999-09-02
Abstract: PCT No. PCT/FR94/01423 Sec. 371 Date Jun. 6, 1996 Sec. 102(e) Date Jun. 6, 1996 PCT Filed Dec. 7, 1994 PCT Pub. No. WO95/16802 PCT Pub. Date Jun. 22, 1995A method of forming a gaseous treatment atmosphere capable of depositing a silicon on a metal substrate comprising the steps of: converting an initial gas mixture into a primary gas mixture in an apparatus for forming excited or unstable gas species, the primary gas mixture comprising excited or unstable gaseous species substantially devoid of electrically charged species, combining the primary gas mixture with an adjacent gas mixture which comprises at least one silicon precursor gas and which has not passed through the apparatus, to form the gaseous treatment atmosphere.
Patent DE-69419824-T2 (DE)
Inventor: WAUTIER HENRI
IPC: C08G63/84
Filed: 1994-05-03
Granted: 2000-02-17
Abstract: Poly- epsilon -caprolactones are manufactured by continuous polymerisation of  epsilon -caprolactone as a melt in an extruder (reactive extrusion) with the use of a polymerisation initiator chosen from aluminium alkoxides. The appropriate adjustment of the feed rates of  epsilon -caprolactone and of aluminium alkoxide to the extruder allows the tailored manufacture of poly- epsilon -caprolactones which have high and preestablished weight-average molecular masses. Poly- epsilon -caprolactones which can be obtained by the process are characterised by weight-average molecular masses (Mw) of at least approximately 95,000 g/mole and Mw/Mn ratios of at least approximately 2.
Patent DE-69421619-T2 (DE)
Inventor: WEBB MARTIN
IPC: G01N33/84
Filed: 1994-07-15
Granted: 2000-03-09
Abstract: PCT No. PCT/GB94/01533 Sec. 371 Date Apr. 24, 1996 Sec. 102(e) Date Apr. 24, 1996 PCT Filed Jul. 15, 1994 PCT Pub. No. WO95/02825 PCT Pub. Date Jan. 26, 1995Disclosed is a method for measuring or detecting inorganic phosphate ion in a sample. In the method, a sample is reacted with a phosphate-binding protein containing (i) an inorganic phosphate ion binding site and (ii) a detectable label that produces a signal whose amplitude changes detectably upon the binding of inorganic phosphate ion to the binding site, under conditions effective to allow binding of phosphate in the sample to the binding site. From a change in signal, the level of inorganic phosphate ion is measured or detected. Also disclosed are phosphate binding proteins for use in the method.
Patent DE-69425085-T2 (DE)
Inventor: NISHIKAWA KOHEI
IPC: C07D417/10
Filed: 1994-04-21
Granted: 2000-11-09
Abstract: This invention relates to prophylactic or therapeutic drug for diabetic nephropathy or glomerulonephritis, comprising, as an active ingredient, a compound or salt thereof represented by general formula (I) <CHEM> wherein R<1> stands for H or an optionally substituted hydrocarbon residue; R<2> stands for an optionally esterified carboxyl group; R<3> stands for a group actually or potentially capable of forming an anion; X shows that the phenylene and phenyl groups bind to each other directly or through a spacer having an atomic chain length of two or less; n stands for 1 or 2; ring A stands for a benzene ring having an optional substituent in addition to R<2>; Y stands for a bond, -O-, -S(O)m- (wherein m stands for 0, 1 or 2), or -N(R<4>)- (wherein R<4> stands for H or an optionally substituted alkyl group).
Patent DE-69426841-T2 (DE)
Inventor: MCCORMICK FRANCIS
IPC: A61K35/76
Filed: 1994-02-16
Granted: 2001-09-06
Abstract: Methods and compositions for treating neoplastic conditions by viral-based therapy are provided. Mutant virus lacking viral proteins which bind and/or inactivate p53 or RB are administered to a patient having a neoplasm which comprises cells lacking p53 and/or RB function. The mutant virus is able to substantially produce a replication phenotype in neoplastic cells but is substantially unable to produce a replication phenotype in non-replicating, non-neoplastic cells having essentially normal p53 and/or RB function. The preferential generation of replication phenotype in neoplastic cells results in a preferential killing of the neoplastic cells, either directly or by expression of a cytotoxic gene in cells expressing a viral replication phenotype.
Patent DE-69427708-T2 (DE)
Inventor: HARIDAS KOCHAT
IPC: A61K31/47
Filed: 1994-12-19
Granted: 2001-10-25
Abstract: 10-hydroxy 7-ethyl camptothecin (HECPT), an active metabolite of the camptothecin analog CPT-11, is poorly soluble in water. Because of its poor water solubility, HECPT has not been directly administered by parenteral or oral routes in human patients for the purpose of inhibiting the growth of cancer cells. There is also unpredictable interpatient variability in the metabolic production of HECPT from CPT-11 which limits the utility of CPT-11. This invention overcomes these limitations by teaching novel pharmaceutically acceptable lactone stable HECPT formulations for the direct administration of HECPT. The claimed invention also describes novel dosages, schedules, and routes of administration of the lactone stable HECPT formulations to patients with various forms of cancer.
Patent DE-69429587-T2 (DE)
Inventor: IONESCU F
IPC: H05B39/04
Filed: 1994-10-25
Granted: 2002-09-05
Abstract: A switchmode AC power controller for controlling the current through a load such as a large lamp array connected to an alternating current source. The controller contains an AC solid state switch, a synchro-flywheel, an output inductor and capacitor. The load current is controlled by triggering signals generated by a synchronized modulator.
Patent DE-69430956-T2 (DE)
Inventor: SCHOESLER HENNING RAUN
IPC: A43B17/03
Filed: 1994-04-15
Granted: 2003-02-20
Abstract: A fluid filled insole comprises a fluid tight bladder having upper and lower layers and a generally foot-shaped planar configuration, with a metatarsal region, a heel region and arch region therebetween; a large-molecular, hygroscopic, sterile liquid substantially filling the bladder, the liquid comprising a mixture of polyvalent alcohol and distilled water; a plurality of spaced metatarsal flow deflectors joining the upper and lower layers in the metatarsal region of the bladder; a plurality of spaced heel flow deflectors joining the upper and lower layers in the heel region of the bladder; longitudinal flow passages between the metatarsal flow deflectors and heel flow deflectors; and a flow restrictor in the arch area of the bladder, whereby liquid flow from the heel area to the metatarsal area and vice versa and flow through the channels between flow deflectors spread the user's weight over a larger area reducing pressure on the plantar surfaces of the user's foot, provides massaging action to the plantar surfaces of the user's foot, improving venepump function and increasing blood circulation with its resulting medical benefits; ensures a liquid pillow on the medial and lateral sides of the user's foot to help against over pronation or over supination during walking; and beneficially stimulates zone therapeutic reflex zones.
Patent DE-69432341-T2 (DE)
Inventor: WASHBURN WILLIAM N
IPC: C07D303/36
Filed: 1994-12-21
Granted: 2004-03-04
Abstract: Compounds of the formula <CHEM>  or pharmaceutically acceptable salts thereof wherein: A is a bond, -(CH2)n- or -CH(B)-, where n is an integer of 1 to 3 and B is -CN, -CON(R<9>)R<9'> or -CO2R<7>;     R<1> is lower alkyl, aryl or arylalkyl; R<2> is hydrogen, hydroxy, alkoxy, -CH2OH, cyano, -C(O)OR<7> , -CO2H, -CONH2, tetrazole, -CH2NH2 or halogen;     R<3> is hydrogen, alkyl, heterocycle or <CHEM>       R<4> is hydrogen, alkyl or B; R<5>, R<5'>, R<8>, R<8'> or R<8''> are independently hydrogen, alkoxy, lower alkyl, halogen, -OH, -CN, -(CH2)nNR<6>COR<7>, -CON(R<6>)R<6'>, -CON(R<6>)OR<6'>, -CO2R<6>, -SR<7>, -SOR<7>, -SO2R<7>, -N(R<6>)SO2R<1>, -N(R<6>)R<6'>, -NR<6>COR<7>, -OCH2CON(R<6>)R<6'> , -OCH2CO2R<7> or aryl; or R<5> and R<5'> or R<8> and R<8'> may together with the carbon atoms to which they are attached form an aryl or heterocycle;     R<6> and R<6'> are independently hydrogen or lower alkyl; and     R<7> is lower alkyl; R<9> is hydrogen, lower alkyl, alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl; or R<9> and R<9'> may together with the nitrogen atom to which they are attached form a hetocycle; with the proviso that when A is a bond or -(CH2)n and R<3> is hydrogen or unsubstituted alkyl, then R<4> is B or substituted alkyl. These compounds are beta3 adrenergic receptor agonists and are useful, therefore for example, in the treatment of diabetes, obesity and gastrointestinal diseases.
Patent DE-69503690-T2 (DE)
Inventor: BALDINI PIERO
IPC: F02N3/04
Filed: 1995-03-24
Granted: 1999-03-18
Abstract: In pedal vehicles with stepless transmission, a drive pulley unit comprising an automatic device for facilitating starting, in which the drive pulley comprises a pair of half pulleys (12, 13) mounted on a shaft (11), the first (12) being axially fixed and the second (13) being axially movable relative to the first, between the two half pulleys there being positioned a drive belt (14) engaging against walls of the two half pulleys (12, 13), which depending on their distance apart determine low gear or high gear, associated with the drive pulley unit there being provided a gear position regulator consisting of a counteracting element (18) associated with the movable second half pulley (13) via radially movable rolling bodies (24) inserted in respective housings (19, 37), wherein to the counteracting element (18) there are connected radially oscillable centrifugal masses (20) which are associated with an elastic element (31) and interact with the rolling bodies (24) at low speeds to cause the half pulleys (12, 13) to assume a position of maximum approach, determining high gear. <IMAGE>
Patent DE-69512608-T2 (DE)
Inventor: GAUTHERON MICHEL
IPC: F16F1/38
Filed: 1995-05-17
Granted: 2000-05-31
Abstract: Resilient support comprising at least two coaxial cylindrical sleeves (10, 20) coupled by a resiliently compressible material (3), the resilient material (3) being compressed by changing the length of the median line of the cross section of one of said sleeves (10) in the direction wherein the median lines of the cross sections of the two adjacent sleeves (10, 20) radially converge. The sleeve (10) with the modified median line includes prelocated longitudinal folds (11), circumferentially uniformly distributed.