baber/WOPTO huggingface dataset:
Patent CY-1122649-T1 (CY)
Title: 5-φαινυλο-[1,2,4]τριαζολο[1,5-α]πυριδιν-2-υλο καρβοξαμιδια ως jak αναστολεις
Inventor: MENET CHRISTEL JEANNE MARIE
IPC: A61K45/06
Filed: 2020-01-09
Abstract: Αξιώνεται μια ένωση του τύπου (I) ικανή να αναστέλλει JAK και θεωρείται σχετική για νόσους οι οποίες συνδέονται με υπερέκκριση της IL6. Αξιώνονται επίσης φαρμακευτικές συνθέσεις και η ένωση ή η σύνθεση για χρήση σε πρόληψη και αντιμετώπιση νόσων όπως φλεγμονώδεις παθήσεις, αυτοάνοσες νόσοι, πολλαπλασιαστικές νόσοι, απόρριψη μοσχεύματος, νόσοι οι οποίες αφορούν διαταραχή της εναλλαγής του χόνδρου και συγγενείς δυσπλασίες χόνδρου.
Patent CY-1122946-T1 (CY)
Title: Μεθοδοι για θεραπεια filoviridαε ιου μολυνσεων
Inventor: CHUN BYOUNG-KWON
IPC: A61K31/675
Filed: 2020-04-14
Abstract: Παρεχόμενες είναι ενώσεις, μέθοδοι και φαρμακευτικές συνθέσεις για θεραπεία Filoviridae ιού μολύνσεων με χορήγηση ριβοσιδίων, φωσφορικών ροβοσιδίου και, προφαρμάκων αυτών, του Τύπου IV:
Patent CY-1123434-T1 (CY)
Title: Λυοφιλοποiημενα νανοεναιωρηματα φαρμακων
Inventor: INGHELBRECHT SABINE KARINE KATRIEN
IPC: A61K9/00
Filed: 2020-09-11
Abstract: Η παρούσα εφεύρεση αφορά σε λυοφιλοποιημένο (που ονομάζεται επίσης λυοφιλιώμενο) νανοεναιώρημα φαρμάκου. Η παρούσα σύνθεση λυοφιλοποιημένου νανοεναιωρήματος φαρμάκου έχει αποδεκτή σταθερότητα κατανομής μεγέθους σωματιδίων κατά την αποθήκευση, συμπεριλαμβανομένης της μακροχρόνιας αποθήκευσης.
Patent CY-1123756-T1 (CY)
Title: Παραγωγα διπυραζολιου ως αναστολεις jak
Inventor: LI YUN-LONG
IPC: A61P37/06
Filed: 2021-01-22
Abstract: Η παρούσα εφεύρεση παρέχει ενώσεις του Τύπου I ή φαρμακευτικώς αποδεκτά άλατα αυτών καθώς επίσης συνθέσεις αυτών και μεθόδους χρήσης αυτών που παρεμποδίζουν τη δραστικότητα κινάσης Janus (JAK) και είναι χρήσιμες στη θεραπεία ασθενειών που σχετίζονται προς τη δραστικότητα JAK που συμπεριλαμβάνουν, για παράδειγμα, φλεγμονώδεις διαταραχές, αυτοάνοσες διαταραχές, καρκίνο και άλλες ασθένειες.
Patent GR-910300142-T1 (GR)
Title: Mounting process for a conductive railsystem and associated connector
Inventor: LEWANDOWSKI SIEGFRIED
IPC: B60M1/34
Filed: 1992-06-30
Abstract: In a method for mounting a rail system consisting of carrier rails (1) and a contact line system (2) which is attached thereto and comprises for each carrier rail (1) at least two parallel current rails (3) which clear a set-back contact surface (4) in each case on one side, the carrier rails (1) are placed in abutment and the current rails (3) are attached with a contact surface (4) facing away from the carrier rail (1) to the respective carrier rail (1) with the aid of support point terminals (5) and the ends (6) assigned to one another of the current rails (3) are subsequently connected to one another with  one  connector  (7)  in  each  case. Here,  a particularly cost-effective mounting is obtained if the current rails (3) are attached to ends (6) which are shortened in comparison with the respective carrier rail (1) to the carrier rails (1) with central longitudinal fixing (shown at 8) before the carrier rails (1) are laid, and after the laying of the carrier rails (1) the connectors (7) are clamped onto the ends (6) of the current rails (3) exclusively by being placed perpendicularly to the contact face (4) towards the carrier rail (1).
Patent HR-P20110392-T1 (HR)
Inventor: ANDRIES KOENRAAD JOZEF LODEWIJK MARCEL
IPC: A61P31/06
Filed: 2011-05-24
Abstract: Uporaba spoja formule (Ia) ili (Ib) za proizvodnju lijeka za liječenje latentne tuberkuloze, naznačena time što je spoj (Ia) ili (Ib) njegova farmaceutski prihvatljiva kisela ili bazna adicijska sol, njegov kvarterni amin, njegov N-oksid, njegov tautomerni oblik ili njegov stereokemijski izomerni oblik pri čemuR1 je vodik, halo, haloalkil, cijano, hidroksi, Ar, Het, alkil, alkiloksi, alkiltio, alkiloksialkil, alkiltioalkil, Ar-alkil ili di(Ar)alkil; p je cijeli broj jednak 1, 2, 3 ili 4; R2 je vodik, hidroksi, merkapto, alkiloksi, alkiloksialkiloksi, alkiltio, mono ili di(alkil)amino ili radikal formulePri čemu Y je CH2, O, S, NH ili N-alkil; R3 je alkil, Ar, Ar-alkil, Het ili Het-alkil; q je cijeli broj jednak nula, 1, 2, 3 ili 4; R4 i R5 su svaki nezavisno vodik, alkil ili benzil; iliR4 i R5 zajedno i uključujući N za kojeg su vezani mogu tvoriti radikal koji je odabran iz skupine koja sadrži pirolidinil, 2-pirolinil, 3-pirolinil, pirolil, imidazolidinil, pirazolidinil, 2-imidazolinil, 2-pirazolinil, imidazolil, pirazolil, triazolil, piperidinil, piridinil, piperazinil, piridazinil, pirimidinil, pirazinil, triazinil, morfolinil i tiomorfolinil, a svaki od navedenih prstenastih sustava je proizvoljno supstituiran sa alkil, halo, haloalkil, hidroksi, alkiloksi, amino, mono- ili dialkilamino, alkiltio, alkiloksialkil, alkiltioalkil i pirimidinil; R6 je vodik, halo, haloalkil, hidroksi, Ar, alkil, alkiloksi, alkiltio, alkiloksialkil, alkiltioalkil, Ar-alkil ili di(Ar)alkil; ilidva susjedna R6 radikala zajedno mogu tvoriti bivalentni radikal prema formuli -CH=CH-CH=CH-;r je cijeli broj jednak 1, 2, 3, 4 ili 5; R7 je vodik, alkil, Ar ili Het; R8 je vodik ili alkil; R9 je okso; iliR8 i R9 zajedno tvore radikal =N-CH=CH-;alkil je ravni ili razgranati zasićeni radikal ugljikovodika koji ima od 1 do 6 atoma ugljika; ili je prstenasti zasićeni radikal ugljikovodika koji ima od 3 do 6 atoma ugljika; ili je prstenasti zasićeni radikal ugljikovodika koji ima od 3 do 6 atoma ugljika koji je vezan za ravni ili razgranati zasićeni radikal ugljikovodika koji ima od 1 do 6 atoma ugljika; pri čemu svaki atom ugljika može biti proizvoljno supstituiran s halo, hidroksi, alkiloksi ili okso; Ar je homocikal odabran iz skupine koja sadrži  fenil, naftil, acenaftil, tetrahidronaftil, a svaki homocikal je proizvoljno supstituiran sa 1, 2 ili 3 supstituenta, pri čemu je svaki supstituent nezavisno odabran iz skupine koja sadrži  hidroksi, halo, cijano, nitro, amino, mono- ili dialkilamino, alkil, haloalkil, alkiloksi, haloalkiloksi, karboksil, alkiloksikarbonil, aminokarbonil, morfolinil, te mono- ili dialkilaminokarbonil; Het je monociklički heterocikal odabran iz skupine koja sadrži  N-fenoksipiperidinil, piperidinil, pirolil, pirazolil, imidazolil, furanil, tienil, oksazolil, izoksazolil, tiazolil, izotiazolil, piridinil, pirimidinil, pirazinil i piridazinil; ili biciklički heterocikal odabran iz skupine koja sadrži  kinolinil, kinoksalinil, indolil, benzimidazolil, be
Patent HR-P20110800-T1 (HR)
Inventor: CHRISTOPHER RONALD J
IPC: A61P31/18
Filed: 2011-11-02
Abstract: 2-[6-(3-amino-piperidin-1-il)-3-metil-2,4-diokso-3,4-dihidro-2H-pirimidin-1-ilmetil]-4-fluoro-benzonitril (Spoj I), naznačen time, što se koristi kao lijek kada se primijeni u tjednoj dozi koja iznosi između 50 mg i 250 mg, pri čemu se tjedna doza primjenjuje jednom tjedno. Patent sadrži još 7 patentnih zahtjeva.
Patent HR-P20120445-T1 (HR)
Title: Process for manufacturing entacapone
Inventor: MARTTI HYTOENEN
IPC: A61P25/16
Filed: 2012-05-24
Abstract: New processes for manufacturing entacapone are provided.
Patent SI-1152116-T1 (SI)
Title: Steel plate door leaf
IPC: E06B3/82
Filed: 2001-03-31
Abstract: The door panel consists of a box-shaped half-liner (1) and a cover sheet (2). At least three edge surfaces (6) have edge strips (3). The cover sheet lies on them and has U-shaped connecting edge sectors forming a hollow door fold (5). There is an offset (7) at the edge surfaces, on which the end of the U-shaped sector forming the door fold lies. -
Patent SI-1667947-T1 (SI)
Title: Methods of 11c -radiolabelling phenothiazine and pheno thiazine-like compounds
Inventor: SCHWEIGER LUTZ F
IPC: A61K31/00
Filed: 2004-09-27
Abstract: This invention pertains to methods of [<SUP>11</SUP>C]-radiolabelling "phenothiazine" and "phenothiazine-like" compounds, which have a pendant group (which is a primary amino group; a cationic primary imino group; a secondary amino group; a cationic secondary imino group; a primary imino group; or a secondary imino group), by reaction with [<SUP>11</SUP>C]methyl trifluoromethanesulfonate (CF<SUB>3</SUB>SO<SUB>2</SUB>O<SUP>11</SUP>CH<SUB>3</SUB>), also known as [<SUP>11</SUP>C]methyl triflate. This reaction converts the pendant group into a [<SUP>11</SUP>C]methyl-labelled pendant group. The resulting [<SUP>11</SUP>C]-radiolabelling product is useful, for example, as an in vivo positron emission tomography (PET) tracer, for example, for patients suffering from melanoma, the most serious form of skin cancer, and tauopathy (e.g., Alzheimer's disease). The present invention also pertains to the resulting [<SUP>11</SUP>C]-radiolabelling products, compositions comprising them, their use in methods of (e.g., PET) imaging, their use in methods of medical treatment and diagnosis, etc.
Patent SI-1729730-T1 (SI)
Title: Tamper resistant dosage form comprising an adsorbent and an adverse agent
Inventor: ABREU OSVALDO
IPC: A61K9/00
Filed: 2005-03-23
Abstract: Pharmaceutical compositions and dosage forms comprising an adsorbent, and an adverse agent, such as an opioid antagonist. In one embodiment, at least a portion of the adverse agent is on the surface or within the micropore structure of an adsorbent material. The pharmaceutical compositions and dosage forms comprising the adsorbent and the adverse agent are useful for preventing or discouraging tampering, abuse, misuse or diversion of a dosage form containing an active pharmaceutical agent, such as an opioid. The present invention also relates to methods for treating a patient with such a dosage form, as well as kits containing such a dosage form with instructions for using the dosage form to treat a patient. The present invention further relates to process for preparing such pharmaceutical compositions and dosage forms.
Patent SI-1800723-T1 (SI)
Title: An amusement ride
Inventor: BUSSINK RONALD ALEXANDER
IPC: A63G7/00
Filed: 2005-12-21
Abstract: An amusement ride comprising:a support structure (1) generally having the shape of a vertical standing arch that spans from a first ground base (2) to a second ground base (3),at least one vehicle (4) movably supported on the structure for carrying one or more passengers at least partially along the length of the structure starting from an initial loading position at one of the first or second ground base (3,4),lifting means for lifting the vehicle from the loading position upwards along the structure (1),breaking means for breaking the vehicle when it travels from an elevated position in a downward direction along the structure (1).
Patent SI-1827386-T1 (SI)
Title: Oral compositions for absorption of phosphorus compounds
Inventor: SAVICA VINCENZO
IPC: A61K33/244
Filed: 2005-11-29
Abstract: The present invention provides medicaments useful for reducing phosphorus serum level, especially in those subjects affected from hyperphosphatemia. More specifically, the present invention relates to pharmaceutical compositions to be administered by oral route in fasting periods, in order to absorb phosphorus compounds from fluids of the enteric tract, especially from saliva.
Patent SI-2990422-T1 (SI)
Title: Humanized anti-beta7 antagonists and uses therefor
Inventor: DENNIS MARK S
IPC: C07K16/00
Filed: 2005-09-02
Abstract: The invention provides therapeutic anti-beta7 antibodies, compositions comprising, and methods of using these antibodies
Patent SI-1963484-T1 (SI)
Title: Method of producing rough strains of bacteria and uses thereof
Inventor: STANFORD JOHN LAWSON
IPC: A61K39/00
Filed: 2006-12-19
Abstract: The present invention relates to an immune modulator composition comprising a whole cell of a rough strain of  Mycobacterium obuense  for use in the treatment or prevention of stress.
Patent SI-2207770-T1 (SI)
Title: 1, 2, 3-triazole derivatives for use as stearoyl-coa desaturase inhibitors
Inventor: BOUILLOT ANNE MARIE JEANNE
IPC: A61K31/4192
Filed: 2008-11-07
Abstract: The present invention relates to substituted triazole compounds of the formula (I) and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
Patent DE-3650560-T2 (DE)
Inventor: FEARON EDWARD ROBERT
IPC: C23C14/14
Filed: 1986-10-13
Granted: 1997-01-02
Abstract: A label for use in a high frequency anti-theft surveillance system. Permanently magnetized members (24, 26) are disposed adjacent a ferromagnetic nonlinear element (30) for biasing the hysteresis loop of the nonlinear element (30) near the knee (40) of the magnetization curve. The nonlinear element (30) includes low permeability sections (32, 34) and high permeability section (36). The high permeability section (36) of the nonlinear element (30) is disposed adjacent a radiating dipole (28) for radiating the summation frequency of a pair of frequencies impinging on the nonlinear element (30). A memory magnet (38) with a changeable magnetism is disposed adjacent the high reluctance section (36) of the nonlinear element (30). The magnetism of the memory magnet (38) can be changed to provide either an active or inactive status of the label (16).
Patent DE-3686819-T2 (DE)
Inventor: PATEL M
IPC: A23L27/30
Filed: 1986-10-15
Granted: 1993-05-13
Abstract: Carbohydrate syrup-plasticizer compositions for use in chewing gums to improve flexibility and methods of preparing the compositions are disclosed. The syrup comprises carbohydrate solids and water, with less than 30% of the solids having a degree of polymerization (DP) of 1 and more than 20% solids with a DP of 4 or greater. The ratio of carbohydrate solids to plasticizing agent in the composition is between 0.5:1 and 100:1 and the total water content of composition is less than 20%. The syrup-plasticizer composition is prepared by providing a carbohydrate syrup or combined syrups with the proper carbohydrate solids distribution, combining a plasticizer such as glycerine or propylene glycol and evaporating water from the combined syrup composition.
Patent DE-3850795-T2 (DE)
Inventor: OTSUJI KAZUYA
IPC: C11D3/22
Filed: 1988-03-07
Granted: 1995-03-09
Abstract: A novel acidic heteropolysaccharide which comprises as its structural units arabinose, mannose, galactose, glucuronic acid, and xylose, at a specific ratio. The polysaccharide can be prepared by culturing a callus induced from a plant belonging to the genus Polianthes L. in a culture medium containing plant hormones. The polysaccharide can be used as a compoinent of agents for external application and detergents, and provides good moisturizing effects and a smooth, satisfying feeling upon use. When formulated in detergents, they produce remarkable improvement in a clean, rich feeling upon use.
Patent DE-3851770-T2 (DE)
Inventor: SORGE JOSEPH A M D
IPC: C12N15/64
Filed: 1988-01-12
Granted: 1995-02-16
Abstract: Vectors are described that circumvent traditional DNA cloning and subcloning procedures, and that contain a unique DNA cartridge that permits both cloning of DNA directly into DNA sequences present within the cartridge, and in vivo removal and circularization of the cartridge thereby yielding an autonomously replicating structure. Because the DNA cartridge can include a wide variety of functional DNA sequences, the cloned DNA can be subjected to a plethora of molecular biological procedures without having to remove the cloned DNA from the cartridge thereby obviating the need to perform additional subcloning technqiues. A particularly useful example of the this type of vector is bacteriophage lambda containing the DNA cartridge.
Patent DE-3873392-T2 (DE)
Inventor: GOETTING ERICH
IPC: H03K19/177
Filed: 1988-04-13
Granted: 1993-04-08
Abstract: One of the programmable elements of the array (20) is designated as a security element (22), and its output is coupled to a latching mechanism (30). The output of the latching mechanism (30) is coupled to a mechanism (36) for disabling the read output of the array (20). The latching mechanism (30) is enabled for a short time by a pulse when power is applied to the circuit. Thus, when power is first applied, the security fuse (22) has not been set and the latch output will allow data to be read. While power is applied, all of the programmable elements can be set, including the security element (22). All the elements, including the security fuse (22), can then be verified by reading them out. When power is turned off and subsequently reapplied, the latch (30) will then be enabled and the set security fuse level will appear at the latch output, thereby disabling the reading out of the program data. The present invention thus allows verification of the setting of the security fuse (22) and verification of the other programmable elements after the security fuse (22) has been set.
Patent DE-3879410-T2 (DE)
Inventor: WALKER FREDERICK JUDSON
IPC: C07D409/12
Filed: 1988-11-17
Granted: 1993-06-24
Abstract: Acyl derivatives of 2-Amino-4-substituted-5-hydroxy pyrimidines, which may be 6-substituted, and derivatives thereof are disclosed. The compounds are inhibitors of leukotriene synthesis and are, therefore, useful for the treatment of pulmonary, inflammatory, dermatological, allergic and cardiovascular diseases. The compounds are also cytoprotective and therefore, useful in the treatment of peptic ulcers.
Patent DE-60004858-T2 (DE)
Inventor: AGUTTES JEAN-PAUL
IPC: H04B7/204
Filed: 2000-06-28
Granted: 2004-06-09
Abstract: The invention concerns a system comprising a radiofrequency antenna stationed in an orbit around the earth, and illuminating means for transmitting and/or receiving likewise orbiting round the earth located on at least a satellite separate from the one bearing the antenna, the antenna being located in the illuminating field of said means. The invention is characterised in that the antenna is a radiofrequency antenna formed by a mesh generation of tiles and phase-shifting means connected thereto, the signals received by the tiles passing through the phase-shifting means before being assembled on said tiles, said phase-shifting and/or delaying means being capable of diverting the radiofrequency signals corresponding to one or several channels transmitted by the illuminating means to send them to the earth along one or several beams and/or of diverting the radiofrequency signals corresponding to one or several beams transmitted from the earth to send them to the illuminating means along one or several channels.
Patent DE-60005515-T2 (DE)
Inventor: PETITJEAN MAURICE
IPC: B05B11/00
Filed: 2000-07-07
Granted: 2004-08-05
Abstract: The invention provides a dispenser for dispensing liquids from a receptacle, the dispenser having a cylindrical and conical body containing a measuring chamber closed at its bottom end by an admission valve and at its top end by a piston provided with a delivery valve and a delivery tube capped by a pushbutton, the body being the result of assembling together two independent elements: a top element carrying the piston and provided with a cylindrical skirt; and a bottom element provided with a sleeve for co-operating with the skirt by leaktight radial clamping so as to define the wall of the measuring chamber, the bottom element being provided with a bushing extending the sleeve coaxially downwards and engaged with leaktight radial clamping inside the neck of the receptacle.
Patent DE-60017748-T2 (DE)
Inventor: COLMAN LEWIS
IPC: A61M16/08
Filed: 2000-06-07
Granted: 2005-12-29
Abstract: This invention is a neonatal airway adapter (10) with a sliding internal passage (54), which virtually eliminates void volumes (112) within the bore (76) of the airways, such that mixing of the exhales pages with void gases is reduced, and the waveform of the breath is maintained without undue distortion. Furthermore, the virtual elimination of void volumes reduces the level of re-breathing. The neonatal airway adapter connects to endotracheal tube adapters is such a way as to nullify the effect of the differing internal diameters (20) and internal lengths which are used in ET adapters currently available. The cross section of the internal bore of the airway through which the breath flows from the ET adapter to the connector of the ventilator is maintained almost constant, especially in the region of the gas sampling point (66), to ensure that reasonable conditions of laminar flow, and accurate sampling are maintained.
Patent DE-60017968-T2 (DE)
Inventor: JANG JIN
IPC: C01B31/02
Filed: 2000-04-25
Granted: 2006-04-13
Abstract: A method of forming carbon nanotubes comprises growing a carbon nanotubes layer on a substrate to have a predetermined thickness by plasma deposition, purifying the layer by plasma etching and repeating the growth and the purification of the carbon nanotube layer.
Patent DE-60018095-T2 (DE)
Inventor: LINDSAY R
IPC: B27N3/06
Filed: 2000-09-11
Granted: 2005-12-29
Abstract: A quality composite board can be manufactured by combining natural fibrous material, resin and a waxy hydrocarbonaceous material wherein the waxy hydrocarbonaceous material is a natural, synthetic or petroleum wax containing from greater than 30 wt % to up to 98 wt % oil content.
Patent DE-60024597-T2 (DE)
Inventor: HOANG SUNG
IPC: H04B3/14
Filed: 2000-01-11
Granted: 2006-07-20
Abstract: Avariable equalizer is described. The variable equalizer provides for independent control of a number of breakpoints in the frequency response of the equalizer so as to allow the equalizer to be readily tuned to compensate for the tilt of coaxial cables over a wide range of characteristic attenuation. In one embodiment, the variable equalizer includes a two port bridge "T" network with variable top and bottom branches that are independently and selectively adjusted to create a desired frequency response. For example, in one embodiment, the top branches include a number of variable RC networks and the bottom branches include a number of variable LR networks. In some embodiments, PEN diodes provide the variable resistance in these LR and RC networks.
Patent DE-60025605-T2 (DE)
Inventor: POPE VICTORIA
IPC: G01N33/543
Filed: 2000-06-08
Granted: 2006-11-09
Abstract: An antigen composition and method for the detection of antibodies to <i>Treponema pallidum</i> and the diagnosis of syphilis are described. The antigen composition contains synthetic cardiolipin and synthetic lecithin. The antigen composition may additionally contain cholesterol and an alcohol. The antigen composition is useful as an immunoreagent in immunoassays for the detection of antibodies associated with <i>T. pallidum</i> infection. The methods are sensitive and specific for <i>T. pallidum</i> infection.
Patent DE-60028687-T2 (DE)
Inventor: STROPPIANA FERNANDO
IPC: E04F15/22
Filed: 2000-08-22
Granted: 2007-02-22
Abstract: The flooring (1) comprises a treading layer (2) extending in a given plane, and supporting formations (5, 6) extending from said treading layer (2) along respective directions of extension, in which at least some (5) of said supporting formations (5, 6) extend with their respective direction of extension (X5), which is oblique with respect to said given plane of the treading layer. The supporting formations (5, 6) comprise first supporting formations (5) in the form of a first array of ribs (5), which are substantially parallel to one another and extend from said treading layer (2) with their respective directions of extension (X5), which are oblique with respect to said given plane of the treading layer, and second supporting formations (6) consisting of a second array of ribs (6), which extend from said treading layer (2) in a substantially orthogonal direction with respect to said given plane of the treading layer (2) and are set crosswise with respect to said first array of ribs (5). <IMAGE>