baber/WOPTO huggingface dataset:
Patent CO-6251283-A2 (CO)
Title: Pirimidil ciclopentanos como inhibidores de proteina cinasa akt
Inventor: BENCSIK JOSEF
IPC: A61K31/517
Filed: 2010-01-29
Abstract: 1.- Un compuesto de la Fórmula:y enantiómeros y sales del mismo, en donde: G es fenilo, naftaleno, un heteroarilo de 5 a 6 miembros o un heteroarilo bicíclico de 9 a 10 miembros, en donde el fenilo, naftaleno, heteroarilo de 5 a 6 miembros o heteroarilo bicíclico de 9 a 10 miembros se encuentran opcionalmente sustituidos con de uno a cuatro grupos Ra;R1 y R1a se seleccionan independientemente de H, Me, Et, -CH=CH2, -CH2OH, CF3, CHF2 o CH2F; R2 es H, -OH, -OMe o F; R2a es H, Me o F; o R2 y R2a son oxo; R3 es H, Me, Et o CF3; R4 es H, heterociclo de 4 a 6 miembros, ciclopropilmetilo o alquilo C1-C4 opcionalmente sustituido con F, -OH o -O(alquilo C1-C3); R5 y R5a se seleccionan independientemente de H, y alquilo C1-C4 o R5 y R5a conjuntamente con el átomo al cual se encuentran unidos, forman un grupo carbonilo, un cicloalquilo de 5 a 6 miembros o un heterociclo de 5 a 6 miembros, en donde el heterociclo tiene un heteroátomo de oxígeno; cada Ra es independientemente halógeno, alquilo C1-C6 cicloalquilo C3-C6, O-(alquilo C1-C6), CF3, OCF3, S(alquilo C1-C6), CN, fenilo, OCH2-fenilo, NH2, NO2, NH-(alquilo (C1-C6) N-(alquilo C1-C6)2, piperidina, pirrolidina, pirazol, piridina, 2-aminopiridina, CH2F, CHF2, -OCH2F, -OCHF2, -OH, -SO2(alquiloC1-C6), C(O)NH2, C(O)NH (alquilo C1-C6) y C(O)N(alquilo C1-C6)2; y j es 1 ó 2; y cuando j es 2, el carbono en anillo j opuesto a NR4 puede reemplazarse con un heteroátomo O.
Patent CO-6382121-A2 (CO)
Title: Compuestos heterociclicos nitrogenados, su preparacion y utilizacion como medicamentos antibacterianos
Inventor: LEDOUSSAL BENOIT
IPC: A61K31/437
Filed: 2011-04-08
Abstract: La invención se refiere a compuestos heterocíclicos nitrogenados de fórmula (I):en la que:R1 representa hidrógeno, (CH2)m-NH2, -(CH2)m-NH(C1-C6)alc, -(CH2)m-N(C1-C6)alc2, -(CH2)m-NH-C(NH)NH2 o -(CH2)m-NH-CH=NH, m es igual a 1 ó 2;R2 y R3 forman juntos un heterociclo nitrogenado de carácter aromático con 5 vértices que contienen 1, 2 ó 3 átomos de nitrógeno, sustituido por R4 en un átomo de nitrógeno;R4 representa hidrógeno, (C1-C6)alc o una cadena de fórmula: -(A)n-(NH)o-(CH2)p-(CHR')q R''; A representa C=O, C=NH o SO2;R' representa hidrógeno o carboxilo;R" representa hidrógeno, NH2, NH(C1-C6)alc, N(C1-C6)aIc2, CONH2, CONH(C1-C6)alc, CON(C1-C6)alc2, o un heterociclo saturado con 5 ó 6 vértices que contienen 1 ó 2 nitrógenos y, llegado el caso, un oxígeno o un azufre, fijado a la cadena mediante un nitrógeno o un carbono y eventualmente sustituido por (C1-C6)alc;n, o y q representan 0 ó 1 y p representa un entero de 0 a 4; R5 representa OSO3H, OCFCO2H o OCF2CO2H;- R1 no es hidrógeno, -(CH2)m-NH2, -(CH2)mNH(C1-C6)alc o -(CH2)m-N(C1-C6)alc2 mientras que R4 es hidrógeno, -(C1-C6)alc, -(C=O)n-(CH2)(0-5)-NH2, -(C=O)n-(CH2)(0-5)-NH(C1-C6)alc o -(C=O)n-(CH2)(0-5)-N(C1-C6)alc2 y R5 es un grupo OSO3H, o cuando R4 tiene todos los valores de R'' mencionados anteriormente, con excepción del heterociclo,-y n, o, p y q no pueden ser todos iguales a 0 salvo cuando R" es hidrógeno o CONH2, CONH(C1-C6)alc2, CON(C1-C6)alc2, o un heterociclo; en forma libre y en forma de zwitteriones y de sales con las bases y los ácidos minerales u orgánicos farmacéuticamente aceptables, su preparación y su utilización como medicamentos antibacterianos.
Patent EP-1021969-A2 (EP)
Inventor: ITO TAKASHI
IPC: A44C25/00
Filed: 2000-01-13
Abstract: A necklace of which the size of the ring portion
is adjustable so that anyone having a thick or a slender
neck can wear a necklace of one size so that it fits her
best. A hook formed by bending a material is provided at
one of the string formed by connecting pearls together
with a string. A ring is formed by engaging the hook in a
valley portion between any adjacent pearls. By engaging
the hook in a different valley, it is possible to change
the size of the ring freely, so that it is possible to
form a ring of the best size for each wearer.
Patent EP-1048679-A2 (EP)
Inventor: HASSEL TILLMANN DR
IPC: C09D175/08
Filed: 2000-04-18
Abstract: An isocyanate containing binding agent having an NCO content of 2-8 wt.% is formed from a mixture of two ethylene oxide containing copolyethers of differing mol. wt.and OH functionality, an ethylene oxide free diol (mol.wt. of 1500-3000), a diisocyanate (mol. wt. of 140-340) and a polyisocyanate (NCO functionality of 2.5-4.5). An isocyanate containing binding agent (I) having an NCO content of 2-8 wt.% is formed from: (A) 20-90 wt.% of an ethylene oxide containing copolyether having an average mol. wt. of 2500-6000, an OH functionality of and an ethylene oxide content of 5-20 wt.%, whereby at least 90 wt.% of the ethylene oxide units occur as a block; (B) 0-50 wt.% , preferably 10-50 wt.% of an ethylene oxide containing copolyether having an average mol. wt. of 1500-3000, OH functionality of 2 and an ethylene oxide content of 40-60 wt.%, whereby less than 20 wt.% of the ethylene oxide units occurs as block; (C) 0-30 wt.% of an ethylene oxide free diol having an average mol.wt. of 1500-3000; (D) 10-30 wt.% of a diisocyanate having an average mol. wt. of 140-340; and (E) 0-10 wt.% of a polyisocyanate having an NCO functionality of 2.5-4.5 whereby the total ethylene oxide content of (A)+(B 5-40 wt.%, the molar ratio of (B) to (A) is 0-3 and the equivalent ratio of the OH content of (A)+(B)+(C) to the NCO content of is less than 0.5. Independent claims are included for: (i) a process for the production of the prepolymer (I) by reaction of (A), optionally with (C) and (D), optionally in the presence of an appropriate solvent at 20-110 degrees C and optionally addition of (B) at the end of the reaction and optional removal of residual monomers of (D), optionally followed by addition of (E); (ii) a polyurethane (II) prepared by reaction of (I) with optionally blocked diamines containing isocyanate reactive hydrog (iii) a process for the coating of substrates by mixing (I) with a curing agent and application of the mixture to a substra and (iv) a substrate, preferably leather coated with the polyurethane (II).
Patent EP-1099593-A2 (EP)
Inventor: MATSUMOTO TADASHI
IPC: B60N2/90
Filed: 2000-06-08
Abstract: A seat reclining system for an automotive vehicle,
arranged to achieve its weight-lightening. The seal reclining system
comprises a locking mechanism having first and second axial sides.
An arm plate is provided such that the first axial side of the locking
mechanism is connected to the arm plate. A seat back of a vehicle
seat is connected to the arm plate. A base plate is provided having
first and second surfaces which are opposite to each other. The base
plate includes an installation portion through which the base plate
is connected to a vehicle floor. The base plate further includes a fixed
portion having the first surface to which the second axial side of the
locking mechanism is connected. Additionally, a reinforcement plate
is provided including a main body section having first and second
surfaces which are opposite to each other. The reinforcement plate
further includes a flange section integral and extended from the
main body section. The flange section extends generally
perpendicular to a plane which passes through a first position
located in front of the fixed portion of the base plate and a second
position located behind the installation portion of the base plate. The
plane is perpendicular to the surfaces of the base plate. The
reinforcement plate is fixed to the base plate in a state where the
first surface of the main body section is in contact with the second
surface of the base plate.
Patent EP-1074340-A2 (EP)
Inventor: MATSUYAMA YOSHINORI
IPC: B24B17/02
Filed: 2000-07-31
Abstract: A target lens shape measuring device for measuring a
target lens shape of an eyeglass lens has a measuring section
including: a template feeler contactable with a periphery of a
template; a first supporting base to which the template feeler
is attached; a first motor and a link mechanism that move the
template feeler and the first supporting base between a measuring
position and a retracted position, wherein the link mechanism
located between the measuring position and the retracted position
is engaged with the first supporting base, and the link mechanism
located at the measuring position is disengaged with the first
supporting base; a second motor that moves the template feeler
and the first supporting base in a radius vector direction of the
template; and a first encoder that detect an amount of movement
of the template feeler and the first supporting base in the radius
vector direction of the template. A calculating section obtains
radius vector information of the template based on the amount of
movement detected by the first encoder.
Patent EP-1081392-A2 (EP)
Inventor: NESCH RALF
IPC: F16B33/02
Filed: 2000-08-04
Abstract: The fitting has a main part with turnable screw. The screw (24) has a thread (36) with a thread axis (40), which is eccentric relative to the rotary axis (30) of the screw in the main part. The thread core (34) is also eccentric to that axis, and the screw thread is eccentric to the thread core. The thread extends over only part of the core circumference. The fitting has a turning angle limiter (44,50) for the screw.
Patent EP-1084994-A2 (EP)
Inventor: LEWIS DAVID L
IPC: C03B9/347
Filed: 2000-08-26
Abstract: A glassware forming mold that includes a body (30 or 92) of heat conductive
construction having a central portion with a forming surface (32 or 32a) for shaping molten glass
and a peripheral portion spaced radially outwardly of the central portion. A plurality of coolant
passages (34a to 34h, 54 to 70) extend in a spaced array through the peripheral portion of the
mold body, and liquid coolant is directed through such passages for extracting heat from the body
by conduction from the forming surface. A plurality of openings (36a to 36q) extend axially into
the body radially between at least some of the liquid coolant passages and the forming surface for
retarding heat transfer from the forming surface to liquid coolant in the passages.
Patent EP-1091022-A2 (EP)
Inventor: KOEPPE ANDREAS
IPC: C23G3/02
Filed: 2000-09-19
Abstract: Pickling device comprises a flow pickling chamber with an inlet opening and a run-off opening and guides and transporting devices for the strip (9) and outlet openings for applying pickling agents to the strip. The outlet openings are formed as flat nozzles in plates (10, 11) of distribution boxes (14-17) which are distributed on zones in the cross and longitudinal direction of the strip. The pickling agent can be adjusted from zone to zone via a supply of distribution boxes.   Preferred Features: The back walls lying opposite the plates of the boxes are formed of a lid (2) and the base (1a) of the chamber housing.
Patent EP-1086754-A2 (EP)
Inventor: LATTA JOHN S
IPC: G06Q10/00
Filed: 2000-09-25
Abstract: In a network-based mail processing system and method of the invention, the originating
presort bureau or node is defined as the first bureau to receive and process mail, usually near the
point of creation. Each presort bureau or node in the network is generally also a destination
bureau or node since each processes mail from other nodes for delivery to recipients in its
respective region by the postal regional sorting centers associated with its destination codes.
Interactive network processing enables higher density of sorts at destination nodes and reduces
overall sorts, postage, and sort costs over non-interactive processing centers. The term "presort
bureau" is used to connote a service bureau or any other entity which is a) part of the enterprise
network, b) processes mail created and entered by itself or by mailers it services, and/or c)
processes mail interactively with other network nodes. A similar network is described for mail-like
items.
Patent EP-1096050-A2 (EP)
Inventor: DYBALLA CHRISTIAN DR
IPC: D06F34/16
Filed: 2000-10-12
Abstract: The method involves using a balance device with ball weights (13) moving freely in a circular track (12) concentric to the drum (2). An imbalance detection unit (6b,c) produces an imbalance signal during rotation or fluctuations in rotation speed. The system is rotated at a speed below its critical rotation speed, or that of its bearing system. The balancing unit is made so that the ball weights are carried in the track at this rotation speed. An evaluation unit (6d) produces the curve of imbalance amount and accelerates the bodies to a rotation speed above the critical speed in the area of the curve minimum or on exceeding a threshold value.
Patent EP-1097814-A2 (EP)
Inventor: TAMURA NOBORU
IPC: B41J2/175
Filed: 2000-11-06
Abstract: An ink storage chamber (36) has an indicator formed from magnetic
material. A float member (50) whose upper position is limited is
housed in the ink storage chamber (36). Two magnetic-field detection
system are provided at a position on the exterior of a sub-tank (3),
at which the detection system can detect a magnetic flux of the
indicator simultaneously, such that the longitudinal direction
of the detection system is oriented vertically with a specified
ink level of the sub-tank sandwiched between the detection system.
On the basis of signals output from the magnetic-field detection
system, it is determined whether the ink level is in any one of
an excessively low ink level state, a state in which injection
of ink must be started, a state in which injection of ink must
be stopped, and an excessively supplied state. Thus, an ink level
in the sub-tank (3) can be controlled within a specific range without
involvement of an undesired increase in the number of sensors.
Patent EP-1113230-A2 (EP)
Inventor: GRUETZKE JOACHIM
IPC: F24C15/20
Filed: 2000-11-14
Abstract: The domestic apparatus (6) is for the illumination of a work place and has at least one decorative and/or at least one functional component (10). From the device leads a light beam path (12), via which from a light source (14) in the apparatus additionally to the work place simultaneously also the at least one decorative and/or functional component (10) can be illuminated. The light beam path extends from the work place illumination device (5) to the rear side of the decorative and/or functional component. The decorative and/or functional unit at least in part areas or in abutting surrounding area is permeable for the light of the light beam path. In the light beam path is a light conductor (26) which conducts the light from thee work place illuminating device to the decorative and/or functional component.
Patent EP-1172786-A2 (EP)
Inventor: TOKUNAGA TSUTOMU
IPC: H01J11/22
Filed: 2000-12-05
Abstract: An object of the present invention is to provide a
plasma display device that enables high-luminosity display
while keeping consumption of power low. After causing
reset discharge to form a wall charge in the dielectric
layer of all discharge cells of a plasma display panel,
pixel data are written by causing selective erasure
discharge to erase, in accordance to pixel data
corresponding to an input video signal, the wall charge
formed in each discharge cell, and sustaining pulses, with
a voltage value of at least 200 volts, are applied
alternately to each row electrode of each row electrode
pair of the plasma display panel to repeatedly cause
sustained discharge to occur only in discharge cells having
residual wall charge.
Patent EP-1111332-A2 (EP)
Inventor: MERETTIG GERHARD
IPC: G01B11/00
Filed: 2000-12-21
Abstract: Photodiode row comprises m photodiode cells. The size relationship between photodiode cells and the light spot is chosen so that the light spot extends over at least three neighboring cells. Each cell has an assigned factor. For each of the m cells the product of the received light energy and the assigned factor is calculated. Then from the sum of the products for the row the light spot position can be calculated. The weighting of individual photodiode cells is used to determine the position of a light spot.
Patent EP-1026436-A2 (EP)
Inventor: VAN BEERSEL JOZEF
IPC: B29C53/80
Filed: 1994-10-27
Abstract: A method is provided of applying an article such as a tape (2) to an elongate substrate
such as a metal pipe (1). The article comprises a heat activatable adhesive (4) and is
wrapped around the pipe. The tape and pipe are heated by applying a high
frequency alternating magnetic field thereto, such that the ratio of the thickness of
the pipe wall to the skin depth is at least 25:1.
Patent EP-1049066-A2 (EP)
Inventor: ALP BURAK
IPC: G06Q50/20
Filed: 2000-03-24
Abstract: A method and system for providing educational material from a teacher
workstation (12) to one or more student workstations (14,16,18, 20, 22) over a
communications network. Data representative of the educational material, mainly
in the form of images, is transmitted from the teacher workstation (12) to
participating student workstations such that images displayed on the teacher
workstation are replicated on each student workstation. The teacher workstation
can restrict access to input devices, such as keyboard and mouse, to the student
workstations during display of the images on the student workstations to ensure
each student focuses their attention on the educational material. The students and
teacher may communicate using a bi-directional data path (46, 56) and the teacher
can take control of the inputs of a student workstation.
Patent EP-1048563-A2 (EP)
Inventor: DONOVAN NEIL J
IPC: B64C9/02
Filed: 2000-04-27
Abstract: A control surface assembly includes: a control surface member; a shaft
attached to the control surface member; a control system connected with the shaft;
and a bearing. The shaft has a longitudinal axis defining an axis of rotation for the
control surface member. The control system is configured to induce rotation in the
shaft about the axis of rotation such that the control surface member rotates
between a first preselected position and a second rotated position. The bearing
includes a first member (12), a second member (16) and a resilient intermediate member (14)
positioned between and attached to the first (12) and second members (16). The first
member (12) is attached to the shaft (26), and the second member (16) is adapted for non-releasable
fixed attachment to the vehicle during operation of the vehicle. In
response to rotation induced by the control system during operation, the first
member (12), the shaft (26) and the control surface member (16) rotate about the axis of rotation
from the preselected to the rotated position, the second member (16) remains fixed
relative to the vehicle, and the intermediate member undergoes angular deflection
and biases the first member (12), shaft (26) and control surface member (16) to rotate toward the
preselected position, such that disabling of the control system causes the control
surface member to return to the preselected position.
Patent EP-1071088-A2 (EP)
Inventor: NISHIZAWA AKIRA
IPC: G11B7/126
Filed: 2000-07-14
Abstract: An optical disc management system for managing phase
change optical discs with disc management data. The disc
management data is peculiar to each disc, and is not erased
after recorded on each disc. A laser beam is controlled so
that optical strength of the laser beam for initialization
is larger than optical strength of the laser beam for
recording and reproduction according to predetermined
initialization requirements, to record disc management data
onto each disc in initialization by the laser beam.
The management data can be recorded unerasably on the disc as the
location and length of an un-initialised area (a) or an excessively
initialised area (c), the location and length being peculiar to each
disc.
Patent EP-1091454-A2 (EP)
Inventor: OKAYASU YASUSHI
IPC: H01R13/639
Filed: 2000-09-25
Abstract: Male and female connector housings 10 and 20 are latched in a fitted state by a locking
arm 40 engaging with a stopping member 16. An upper face of an operating member
44 at a posterior end of the locking arm 40 forms an inclined face 50, this face 50 being
inclined gradually downwards towards the anterior. An anterior end of the inclined face
50 rises abruptly upwards, forming a counteracting wall 51. In the case where the two
housings 10 and 20 are to be separated, a finger F presses the operating member 44,
causing the locking arm 40 to incline and release the lock. The upper face of the
operating member 44 is concave, with the contacting wall 51 at its anterior end.
Consequently, the location for placing the finger F during the pressing operation is
clearly defined, and the finger is prevented from sliding forwards during the pressing
operation. As a result, the pressing operation of the operating member 44, that is, the
lock-releasing operation, can be performed smoothly.
Patent EP-1091344-A2 (EP)
Inventor: YEUNG STEVE W L
IPC: G02F1/133
Filed: 2000-10-02
Abstract: The invention relates to a protocol for driving a liquid crystal display,
in which a row (common) matrix is made up of orthogonal block-circulant
matrices which can be generated by nonlinear programming
or alternatively by paraunitary matricing.
Patent EP-1103236-A2 (EP)
Inventor: FRASER ROBERT
IPC: A61F2/46
Filed: 2000-11-23
Abstract: A spinal fixation assembly includes a fusion cage to which a plate is mated. The plate is
configured to receive, retain and orient bone screws.
Patent EP-1087704-A2 (EP)
Title: Atherectomy power control system
Inventor: HIRST PAUL A
IPC: A61B19/00
Filed: 2000-03-09
Abstract: A power control system maintains the power dissipated by an atherectomy burr during an ablation procedure at or below a predetermined threshold. A power control circuit monitors the speed and torque provided by a prime mover that rotates the ablation burr in order to calculate the power dissipated under no-load conditions. During ablation, the power dissipated is determined and the no-load power is subtracted to calculate the ablation power. The control circuit adjusts the speed of the prime mover to maintain the ablation power at or below the predetermined threshold.
Patent EP-1165555-A2 (EP)
Inventor: YUAN JUN
IPC: A61P25/14
Filed: 2000-03-10
Abstract: Disclosed are compounds of formula (I) or pharmaceutically acceptable non-toxic salts or pharmaceutically acceptable solvates thereof wherein: (II) represents (a), (b), (c) or (d) and W, X, Y, A, B, C, D, E are variables as described herein. These compounds are highly selective agonists or antagonists at NK3 receptors or prodrugs thereof. The novel tachykinin NK-3 receptor antagonists contained in this invention have potential utility in the treatment of a broad array of disorders and diseases of the central nervous system (CNS) and periphery in mammals in which activation of NK-3 receptors is of importance.
Patent EP-1192762-A2 (EP)
Inventor: SKIRMONT DAVID A
IPC: H04L12/56
Filed: 2000-03-17
Abstract: A method optimizes performance in a data network including a plurality of ingress ports and output queues. Ingress rates of a plurality of flows are monitored, where each flow includes a sequence of packets passing from an ingress port to an output queue and each flow has a profile related to flow characteristics. Each packet is marked with a marking based on criteria including the ingress flow rate and the flow profile. A drop probability of each packet is adjusted at an output queue according to a value of a drop function taken as a function of a queue size. The drop function is selected according to the marking on the packet. The drop functions are zero for queue sizes less than a lower threshold range and positive for queue sizes greater than the lower threshold range. By selecting drop functions according to ingress flow rate measurements and flow profiles, the data network can be optimized for overall system performance.