baber/WOPTO huggingface dataset:
Patent IL-124699-A0 (IL)
Title: Method for identifying compounds for inhibition of neoplastic lesions
IPC: C12Q1/533
Filed: 1998-05-29
Abstract: There is disclosed the use of a compound in the manufacture of a medicament for treating neoplasia, wherein said compound is identified by determining the cyclooxygenase inhibitory activity of the compound; and determining the cGMP-specific PDE inhibition activity of the compound by evaluating that activity against cGMP-specific PDE enzymatic activity; wherein cyclooxygenase inhibitory activity lower than inhibitory activity of said cGMP-PDE activity is indicative that the compound has potential for treating neoplasia.
Patent IL-135108-A0 (IL)
Title: Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
IPC: C07D243/08
Filed: 1998-10-27
Abstract: Heteroaryl diazacycloalkane derivatives (I) are new. Heteroaryl diazacycloalkane derivatives of formula (I) and their enantiomers or mixtures, isotopes and salts are new. [Image] n : 1-3 m : 0-2; R : H, alkyl, cycloalkyl, cycloalkylalkyl or aralkyl; R 1>aminophenyl; nitrophenyl; hydroxyphenyl; alkoxyphenyl; monocyclic 5-6 membered heterocyclyl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino, NO 2, COOR 3, CONR 2R 3, NHCO 2R 2and/or OCONR 2R 3); aryl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2); X-alkyl-Y-alkyl (optionally alkyl substituted by alkoxy or thioalkoxy); X-(alkyl) o-aryl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylene-dioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2); X-(alkyl) o-Z (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2), monocyclic 5-6 membered heterocyclyl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2) (sic), bicyclic heterocyclyl comprising a 5-6 membered monocyclic heterocyclyl fused to a benzene ring (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, alkoxy-alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino, NO 2, aryl optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amine and/or NO 2) or monocyclic 5-6 membered heterocyclyl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2); X, Y : O, S or NH, N-alkyl or Se; o : 0 or 1 and Z : 5-6 membered monocyclic heterocyclyl. ACTIVITY : Analgesic; Neuroprotective; Nootropic; Tranquilizer; Antiinflammatory; Antiaddictive; Antismoking; Anticonvulsant; Neuroleptic; Antidepressant; Antiasthmatic; Antianginal; Antimigraine. The affinity of 1-(6-chloro-5-methoxy-3-pyridyl)-homopiperazine fumaric acid salt for nicotinic Ach receptors was investigated in a test for in vitroinhibition of 3H-cytisine binding. The compound exhibited and IC 50value of 0.0007 mu M. MECHANISM OF ACTION : Nicotinic acetyl choline receptor ligand.
Patent IL-148637-A0 (IL)
Title: Method for producing anntibiotic composites
IPC: A61K9/14
Filed: 2002-03-12
Abstract: A carboxylate, sulfate, sulfamate, sulfonate, disulfate, disulfonate or trisulfonate salt of an aminoglycoside, lincosamide or tetracycline antibiotic is used as a binder for the production of antibiotic composites. Production of antibiotic composites comprises the synthesis of a plastic deformable salt (I) from one or more protonated aminoglycoside, lincosamide or tetracycline antibiotics (A) and one or more aliphatic carboxylates, alkyl, aryl, alkylaryl, cycloalkyl or alkylcycloalkyl sulfates, sulfamates or sulfonates, fatty acid-2-sulfonates, alkyl or cycloalkyl disulfates, alkyl, cycloalkyl, aryl or alkylaryl disulfonates or aryl or alkylaryl trisulfonates (B) and the application of the salt as a binder for the fixation of organic and/or inorganic composite components, optionally with the addition of water.
Patent IL-151667-A0 (IL)
Title: A METHOD OF PRODUCING IgG
IPC: C07K16/06
Filed: 2001-03-29
Abstract: A method for producing IgG from plasma for medical applications, comprising at least: (i') removal of albumin resulting in an IgG fraction, (ii') purifying IgG from an IgG fraction, which is derived from the IgG fraction obtained in step (i'), by adsorbing IgG to a cation exchanger and collecting the adsorbed IgG fraction, and (iii') virus inactivation in an IgG fraction derived from the IgG fraction collected in step (ii'). The method is characterized in; (I) concentrating the IgG fraction obtained in step (i'), (II) adjusting pH to 4±0.1 in the IgG fraction released from the cation exchanger in step (ii'), and preferably maintaining the pH below 6.0 during the remaining steps of the method; and (III) carrying out the virus inactivation (step iii') by using chemicals at a temperature of 30° C.±2° C. for at least 4 hours. Anticomplementary activity is typically below 1 CH50/mg immunoglobulin.
Patent IL-152217-A0 (IL)
Title: Water treatment apparatus
IPC: B01D63/10
Filed: 2002-02-12
Abstract: A water treatment apparatus according to the present invention includes a plurality of composite reverse osmosis membrane modules arranged in multi-stages, each of the modules including a porous support and a polyamide skin layer formed on the porous support. In this apparatus, the module at the final stage is supplied with some of permeated water obtained from at least one module preceding the module at the final-stage, and a rest of the permeated water is discharged from or recovered in the apparatus along with permeated water obtained from the final-stage module.
Patent IL-176280-A0 (IL)
Title: L-(-)-moprolol l-(+)-tartrate
IPC: C07C59/255
Filed: 2006-06-13
Abstract: L-(-)-moprolol L-(+)-tartrate salt (2:1), method for preparing it and pharmaceutical composition comprising it.
Patent IL-185529-A0 (IL)
Title: A method of producing a glazed cereal product with isomalt and cereal products produced thereby
IPC: A23L7/10
Filed: 2007-08-27
Abstract: The present invention relates to cereal products comprising cereals and a mixture of 1,6-GPS and 1,1-GPM, methods for the production thereof and the use of a mixture comprising 1,6-GPS and 1,1-GPM for producing cereal products.
Patent IL-198277-A0 (IL)
Title: An end closure of a container primarily intended for beverages
Filed: 2009-04-21
Abstract: Disclosed is a plastic lid for a container, which has a mounting hole in the lid's center and an in-and-out hole that is tightly closed until opened for the first time, and which has a plastic opening mechanism that can additionally pivotally cover the in-and-out hole. The opening mechanism has a valve that has a hole around which there are at least two latches which interact with a knob that has an arm terminated with a cylindrical element that has at least one carrier and is able to rotate in the mounting hole. The valve and the knob are sealed and immobilized with a plastic foil. Once opened, the in-and-out hole can be covered again using the valve and the mouth contact area using a plastic hygienic cover.
Patent RO-133495-A0 (RO)
Title: Thermally insulating box for food storage
Inventor: LASZLO LUKACS
IPC: B65D81/38
Filed: 2019-03-21
Abstract: The invention relates to a thermally insulating box meant for food storage, suitable to be mounted on a motor vehicle. According to the invention, the box consists of a rectangular body (1) made of a thermally insulating material, joined with some aluminium profiles (11a, 11b and 11c), provided with a door (2) around which some sealing members (4) are fixed, attached at the bottom with some hinges (5, 6, 7, 8 and 9), and having, at the top, a stainless steel lock (10) with a key, supported, when opened, by two metal chains (12 and 13), while, inside the body (1), plywood separators (14) may be attached for orderly storing the food.
Patent RO-135968-A0 (RO)
Title: Unversal support for children's hygiene
Inventor: ŢIGĂNAŞU RADU
IPC: A47K7/08
Filed: 2022-02-28
Abstract: The invention relates to a support for children's hygiene, especially intimate hygiene, to be used on a planar or inclined surface, such as, for example, on a sink, bidet, toilet bowl, bathtub or shower cabin. According to the invention, the support has a toilet support (1) for children or two side sectors of toilet support (1) for children, having a convenient communication space (19) in its/their front part to allow the access of an operator's hand, a chassis (2) with an approximately oval outer contour, with an internal cut-out in the shape of the figure "8", which can be overlapped over the upper edges of a sink or bidet, can be fixed in multiple positions with some elements (4) of attachment to the faucet of a sink or bidet or is supported by some removable, adjustable or fixed lower supports (8), or to a lower cylinder segment, conveniently cut and deformed, perpendicular to the chassis (2), when used on a planar or inclined surface, where the peripheral area of a first inner cut-out (16) of the chassis (2), corresponding, for example, to the upper half of the figure "8", supports the child's bottom, and a second inner cut-out (3), corresponding, for example, to the lower half of the figure "8", provides space for the operator's hand and the water jet, to perform the child's intimate washing through the space (19) of communication between the two inner cut-outs (3 and 16), a fixed or adjustable backrest (5) having a central groove (17) for the spinous processes of the spine, some safety belts (9), some support arms (10), some side telescopic rods (6), and some supports (7) for the lower part of legs provided with a connection piece (15).
Patent MW-2182-A1 (MW)
Title: Seismic recording
IPC: G01V1/26
Filed: 1982-05-19
Abstract: A method and apparatus for indicating the time-break on a seismic record wherein the time-break is marked in response to the rupture of an electric circuit by the explosive charge used to generate the seismic waves. The preferred rupturable electric circuit is connected to the same energy source as the electric detonator used to initiate the explosive charge and the preferred electric detonator is one connected to a high frequency A.C. firing energy source through a transformer, the rupturable electric circuit being the primary or secondary circuit of the transformer. The method is more accurate than the present method of marking the time-break at the initial application of current to the detonator.
Patent AT-500529-A1 (AT)
Title: Elimination of bovine spongiform enzephalopathy from excrement of cattle or the excrement produced substances and excrement liquid, comprises detecting the substance similar to neopterin by high speed liquid chromatography
Filed: 2004-01-05
Abstract: The elimination of bovine spongiform enzephalopathy from excrement of cattle or the excrement produced substances and excrement liquid, comprises detecting the substances similar to neopterin by high-speed liquid chromatography (HPLC). The excrement liquid is obtained by a centrifugation of the diluted excrement of the cattle and is separated from impurities by a cellulose membrane in 3 ml water. A chromatogram is created with a fluorescence detector with a detection wavelength of 438 Nm and an excitation wavelength of 353 Nm. The elimination of bovine spongiform enzephalopathy from excrement of cattle or the excrement produced substances and excrement liquid, comprises detecting the substances similar to neopterin by high-speed liquid chromatography (HPLC). The excrement liquid is obtained by the centrifugation of the diluted excrement of the cattle and is separated from impurities by a cellulose membrane in 3 ml water. A chromatogram is generated with a fluorescence detector with a detection wavelength of 438 Nm and an excitation wavelength of 353 Nm. The obtained liquid (0.01 ml) is evaporated and dissolved with 0.1 ml of mixture from 0.1 mol/l NaOH and 0.1 mol/l iodine in Al, is separated from insoluble material by the centrifugation, is left at ambient temperature for 1 hour, and is injected into the HPLC device. The detection is carried out by radioimmunoassay (RIA) or radioactive enzyme-linked immunosorbent assay (ELISA). The excrement of the cattle is centrifuged for 10 minutes for the production of excrement liquid, which is frozen. The excrement fluid with 0.05 ml is mixed with a marked anti-neopterin anti-bodies substance (0.1 ml). Six standards of neopterin are used for the detection of the substance. The marker substance is a solution from iodine-125-neopterin. The produced mixtures are left for one hour, are mixed with 1 ml per washing solution, and centrifuged for 10 minutes. The radioactivity of each individual mixture is measured for 1 minute, by a gamma counter. A mass spectroscopy, and a light absorption in the ultraviolet, visible, infrared or Roentgen region are used as the detection procedure.
Patent IE-910245-A1 (IE)
Title: Process for producing n-phosphonomethylglycine
Inventor: JR DONALD LEE FIELDS
IPC: C07B61/00
Filed: 1991-01-24
Abstract: A process is provided to produce N-phosphonomethylglycine by the oxidation of N-phosphonomethyliminodiacetic acid to form an intermediate N-phosphonomethyliminodiacetic acid-N-oxide with a peroxide in the presence of an effective amount of a catalyst selected from the group consisting of water-soluble tungsten compounds and a mixture of water-soluble tungsten compounds and a water-soluble molybdenum compound to form the intermediate, and thereafter converting the intermediate N-phosphonomethyliminodiacetic acid-N-oxide to N-phosphonomethylglycine.
Patent MA-44817-A1 (MA)
Title: Préparation naturelle anti-poux
Inventor: REMMAL ADNANE
IPC: A61P33/14
Filed: 2019-02-07
Abstract: L'objet de la présente invention est l'utilisation d'une composition huileuse contenant des huiles essentielles comme produit de contrôle des ectoparasites
Patent MA-55400-A1 (MA)
Title: Piston destiné à être utilisé dans une seringue de rapport dimensionnel spécifique d'une structure d'étanchéité
Inventor: HETTING MIKKEL
IPC: A61M5/315
Filed: 2014-06-04
Abstract: La présente invention concerne un piston destiné à être utilisé dans un injecteur comprenant un cylindre présentant un axe longitudinal et une paroi interne, ledit piston comprenant un élément d'étanchéité déformable doté d'une surface convexe, ledit élément d'étanchéité déformable, lorsque le piston est inséré dans le cylindre, venant buter contre la paroi interne du cylindre au niveau d'une interface de butée et assurant l'étanchéité d'un espace annulaire entre le piston et la paroi interne du cylindre, l'interface de butée et l'élément d'étanchéité déformable présentant des dimensions axiales parallèles à l'axe longitudinal, caractérisées en ce que le rapport entre la dimension axiale de l'interface de butée et la dimension axiale de l'élément d'étanchéité déformable se situe dans la plage comprise entre 0,01 et 0,2. Selon d'autres aspects, l'invention concerne un injecteur comprenant le piston et l'utilisation dans une seringue jetable du piston. Le piston permet d'empêcher le remplissage d'une seringue.
Patent UY-29462-A1 (UY)
Title: Plataforma complementaria del entrenamiento para futbolistas
Inventor: ZIMET LILIAN
IPC: A63B69/00
Filed: 2006-04-07
Abstract: Este útil creado como herramienta para mejorar la práctica y fundamentos del deporte del fútbol para ambos sexos como complemento individual o colectivo del entrenamiento del deportista; para que se intente con esto mejorar la habilidad y la mentalización en la ubicación de la pelota y como golpearla con los pies o la cabeza. Es funcional, es de madera, portátil y requiere de escalón con dos elementos auxiliares y varios optativos de diferentes alturas para soportar una pelota de fútbol, los que serán apropiados para los ejercicios que determine el deportista o el entrenador, dentro de un campo de fútbol, un área cerrada o un gimnasio.
Patent UY-29821-A1 (UY)
Title: Derivados de 5,6-dihidropirazolo(3,4)(1,4)diazepin-4(1h)-ona, procesos de preparación de dichos derivados, composiciones farmacéuticas conteniéndolos y aplicaciones.
Inventor: SJO PETER
IPC: A61K31/5513
Filed: 2006-09-29
Abstract: La presente invención proporciona un compuesto de fórmula (I): en donde las variables son como se definen en la presente; un procedimiento para preparar dicho compuesto; y el uso de dicho compuesto en el tratamiento de un estado de enfermedad mediado por la PDE4.
Patent UY-30000-A1 (UY)
Title: Compuestos aromaticos sustituidos, composiciones farmaceuticas conteniendolos, procesos de preparación y aplicaciones.
Inventor: MOHAMMED RUKHSANA TASNEEM
IPC: C07C311/03
Filed: 2006-12-11
Abstract: La invención se refiere a compuestos aromáticos sustituidos como compuestos farmacéuticos útiles para el tratamiento de trastonos respiratorios, composiciones farmacéuticas que los contienen y procesos para su preparación.
Patent ES-178641-A1 (ES)
Title: Un método mejorado para obtener imagenes coloreadas
IPC: G03B33/00
Filed: 1947-06-26
Abstract: En la etapa de toma y/o proyección, o producción y/o reproducción de cualquier método de producir o reproducir imágenes en colores, el paso de dividir la banda de longitudes de onda que se usaría normalmente para tomar, proyectar, producir y reproducir, y que normalmente hubiera actuado durante el período de toma, proyección, producción o reproducción, en un número de impulsos, pulsaciones u oscilaciones de color, cada uno de los cuales actúa durante uno o más partes fraccionales, alicuotas o no según se desee, del tiempo que sería ocupado normalmente para la toma, proyección, producción o reproducción en el sistema en cuestión.
Patent ES-180297-A1 (ES)
Title: Un metodo par la television en colores
IPC: H04N11/12
Filed: 1947-10-29
Abstract: Método para la transmisión de señales caracterizado por desarrollar una pluralidad de señales individuales o de grupos de señales que representan una imagen óptica representando cada una de dichas señales o grupos de señales porciones de una imagen óptica en grados diferentes de resolución de la imagen para al menos algunas de las porciones de la imagen y transmitir concomitantemente dichas representaciones de señal.
Patent ES-181739-A1 (ES)
Title: APARATO PARA LA INSTRUCCIoN PRáCTICA DE APUNTADORES EN TODA CLASE DE ARMAS, EN ESPECIAL PARA CANONES Y AMETRALLADORAS
Filed: 1948-01-17
Abstract: Aparato para instrucción práctica de apuntadores basado en la siguiente idea fundamental. Que las referencias o blancos utilizados para efectuar la puntería son fijos, pero que se las da apariencia de móviles, verificando desplazamientos en elevación y orientación, de los ejes ópticos de los visores o anteojos de puntería, con lo cual se consigue que para los apuntadores, las referencias o blancos, tengan movimiento.
Patent ES-183582-A1 (ES)
Title: UNA MEJORA EN LOS ANALIZADORES DE IMáGENES COLOREADAS
Filed: 1948-05-05
Abstract: Mejoras en los analizadores de imágenes coloreadas, caracterizadas por la interposición, entre el sistema de análisis sucesivos de los colores componentes y los receptores de tubos acumuladores de imágenes controlados por conmutadores sincrónicos y que ofrecen una modulación no interrumpida en cada vía que conduce a un tubo receptor que reconstituye un color elemental.
Patent ES-190572-A1 (ES)
Title: UN DISPOSITIVO PARA LA CONSTRUCCIoN IN SITU DE CONDUCCIONES DE HORMIGoN
Filed: 1949-11-26
Abstract: Dispositivo para la construcción in situ de conducciones de hormigón caracterizado por un tubo-molde de materia flexible con un fondo metálico en uno de sus extremos en el que hay dispuestas tubuladuras para paso del agua y del aire y en el otro extremo cerrado por un estrechamiento progresivo va un tapón para enganche de un muelle o tubo perforado lateralmente que por su otro cabo acopla a la tubuladura de salida del líquido pudiendo llevar también en el extremo cerrado progresivamente una prolongación de tubo flexible que parte empalmada de otro tubo acoplado a dicho extremo.
Patent ES-191845-A1 (ES)
Title: UN SISTEMA DE PRENSA MECáNICA DE HUSILLO
Filed: 1950-02-27
Abstract: Sistema de prensa mecánica de husillo, caracterizado por cuatro barras verticales que sirven de soporte para el órgano motor y de resbaladeras para el plato superior y van fijamente sujetas a la base y plato inferior, uniéndose por arriba a un puente, cuya posición para diferentes alturas útiles se regula con tornillos.
Patent ES-197182-A1 (ES)
Title: UN DISPOSITIVO DE ANCLAJE DEL DISCO PORTAZAPATAS PARA FRENOS DE AUTOVEHiCULOS DE SUSPENSIoN ELáSTICA
Filed: 1951-03-29
Abstract: Dispositivo de anclaje del disco porta-zapatas para frenos de autovehículos con suspensión elástica caracterizado porque el disco porta-zapatas va montado loco sobre el pivote de la rueda a la cual. es aplicado y está unido por un vástago y las articulaciones correspondientes con una parte fija y suspendida del bastidor del vehículo siendo la orientación del vástago perpendicular o casi perpendicular a la recta o a la curva trazada por el pivote de la rueda durante el desplazamiento permitido por la suspensión.
Patent ES-259996-A1 (ES)
Title: Copolymer dispersions
IPC: C08F2/08
Filed: 1960-07-29
Abstract: Stable dispersions of copolymers in organic liquids in which they are insoluble are made by polymerizing ethylenic monomers having significantly different degrees of polarity in an organic liquid of the said type, and in the presence of a block of graft copolymer of which one constituent is solvated by the organic liquid and another is compatible with the copolymer and becomes associated with the particles thereof, the composition of the copolymer being controlled as it is formed by the addition of one or more of the monomers during the reaction. The monomer mixture may contain two or more components, and mixtures are specified in which the monomers are selected from acrylic and methacrylic acids and their esters and amides, vinyl esters, acrylonitrile, styrene and vinyl toluene. The examples describe the application of the process to the polymerization of: (1) methyl methacrylate and methacrylic acid in white spirit containing degraded rubber (2) monomers as in (1) but using toluene in place of white spirit (3) methyl methacrylate and methacrylamide in toluene containing degraded rubber (4) acrylonitrile and butyl acrylate in toluene containing degraded rubber (5) methyl and lauryl methacrylates in ethanol containing polyacrylic acid and (6) methyl methacrylate, ethyl acrylate and methacrylic acid in white spirit containing crepe rubber. Benzoyl peroxide was used as catalyst in each instance. Specification 941,035 is referred to.