baber/WOPTO huggingface dataset:
Patent EA-000469-B1 (EA)
Title: Preparation of bicyclohexane derivative
Inventor: ROBEY ROGER L
IPC: C07C227/24
Filed: 1996-06-25
Abstract: 1. A process for the preparation of (+)-2-aminobicyclo[3.1.0]-hexane-2-6-carboxylic acid, or a pharmaceutically acceptable salt thereof, which comprises hydrolysing (-)-2-spiro-5'-hydantoinbicyclo[3.1.0]hexane-6-carboxylic acid or a salt thereof, and optionally forming a pharmaceutically acceptable salt. 2. A process as claimed in Claim 1, in which the hydrolysis is performed in the presence of an acid or base as catalyst. 3. A process as claimed in Claim 2, in which the catalyst is hydrochloric acid, hydrobromic acid, an alkali metal carbonate, an alkali metal hydroxide or an alkaline earth metal hydroxide. 4. A process as claimed in any one of Claims 1 to 3, in which the hydrolysis is performed in water. 5. A process as claimed in any one of Claims 1 to 3 in which the hydrolysis is performed at a temperature in the range of from 0 to 130 degree C. 6. A process as claimed in Claim 5, in which the hydrolysis is performed under reflux conditions. 7. (-)-2-Spiro-5-hydantoinbicyclo[3.1.0]hexane-6-carboxylic acid, or a salt thereof. 8. A compound as claimed in Claim 7 which is (-)-2-spiro-5-hydantoinbicyclo[3.1.0]hexane-6-carboxylic acid or (-)-2-spiro-5-hydantoinbicyclo[3.1.0]hexane-6-carboxylic acid, (R)-1-phenylethylamine salt. 9. 2-oxobicyclo[3.1.0]hexane-6-carboxylic acid, or a salt thereof. 10. A compound as claimed in Claim 9, which is (+)-2-oxobicyclo[3.1.0]hexane-6-carboxylic acid or (+)-2-oxobicyclo[3.1.0]hexane-6-carboxylic acid, (S)-1-phenylethylamine salt.
Patent EA-005898-B1 (EA)
Title: Mobile ground two coordinate radar station of circular scan in meter band
Inventor: BOMSTEIN ALEXANDER DAVIDOVICH
IPC: G01S7/36
Filed: 2004-06-09
Abstract: This invention pertains to radar systems and can be used for the detection and position measurement of airborne targets and target designation in terms of range and azimuth. The proposed invention expands the arsenal of the metric-waveband (VHF) 2-D surveillance radars and permits of the consumer interest in these radars to be raised, which is achieved through an integrated approach to implementation of functional and structural components, namely a frequency agile transmitter-receiver subsystem comprising a solid-state transmitter (1), waveform shapers (2) and (3), and a primary-channel receiver (4); a primary radar antenna (5) with an orientation sensor; a noise jamming cancellation subsystem including a jamming cancellation antenna (6), a cancellation channel receiver (7), and a jamming canceller (8); a primary signal processing subsystem consisting of a far-zone signal detector (9) and a near-zone signal detector (10), a switching multiplexer (11), a primary antenna sidelobe blanker (12), a jammer direction-finder (14), and a coordinate measuring unit (13); a secondary processing and interface subsystem (16); and an operator position comprising display, control and test facilities (15) with the necessary interconnections. The radar equipment is accommodated in the cabin of a vehicle, which is divided by a noise-absorbing wall with a door into a crew compartment containing the operator position with display, control and test facilities (15) and the secondary processing and interface subsystem (16), and an equipment room containing an equipment cabinet with the transmitter-receiver subsystem (1-4), the primary processing subsystem (9-14), the cancellation channel receiver (7), and the jamming canceller (8); a cooler-based combined extract-and-input system mounted under the cabin provides cooling for the equipment inside the cabinet and air conditioning for the crew compartment. The solid-state transmitter (1) of the transmitter-receiver subsystem contains a large number (over ten) of sealed power-amplifier modules, whose outputs are summed up. The jamming cancellation antenna is a stationary structure and comprises four radiators mounted in pairs at right angle in the horizontal plane on two masts positioned on the opposite sides of the primary radar antenna so that the angle between any two radiators in the horizontal plane is 90 degree.
Patent EA-007093-B1 (EA)
Title: Bacterial transforming agent
Inventor: LEVEY MICHAEL ERNEST
IPC: A61K31/43
Filed: 2003-06-02
Abstract: A method of increasing the sensitivity of a bacterial strain to a cell-wall active antimicrobial agent, to which the bacterial strain or a progenitor strain from which the bacterial strain has evolved is sensitive is described. The method comprises the step of exposing said bacterial strain to a transforming agent having the following formula (I): where moieties R, and Rare each independently selected from alkyl, alkyloxy, alkyloxycarbonyl, alkylcarbonyloxy, alkenyl, alkenyloxy, alkenyloxycarbonyl, alkenylcarbonyloxy, alkynyl, alkynyloxy: alkynyloxycarbonyl, alkynylcarbonyloxy, each of which may be substituted or unsubstituted, straight chain or branched or cyclic, aryl, aryloxy, aryloxycarbonyl, arylcarbonyloxy, each of which may be substituted or unsubstituted and cabamoyl,moiety Ris selected from alkyl, alkyloxy, alkylcarbonyloxy, alkenyl, alkenyloxy, alkenylcarbonyloxy, alkynyl, alkynyloxy, alkynylcarbonyloxy, each of which may be substituted o unsubstituted, straight chain or branched or cyclic, aryl, aryloxy, arylcarbonyloxy, each of which may be substituted or unsubstituted, and carboxyl, other than R, R, and Rare not all H, and Y is selected from a natural amino acid side chain. The use of an agent having the above formula in the manufacture of a medicament for increasing the sensitivity of a bacterial strain infecting, colonising or being carried by a patient, to an cell-wall active antimicrobial agent is also disclosed.
Patent EA-010027-B1 (EA)
Title: 3-aminopyrrolidine derivatives as modulators of chemokine receptors
Inventor: XUE CHU-BIAO
IPC: C07D409/08
Filed: 2003-11-26
Abstract: The present invention relates to 3-aminopyrrolidine derivatives of the formula I:(wherein R, R, R, R, R, R, R, R, X, Y and X are as defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of chemokine receptors and more specifically as a modulator of the CCR2 and/or CCR5 receptor. The compounds and compositions of the invention may bind to chemokine receptors, e.g., the CCR2 and/or CCR5 chemokine receptors, and are useful for treating diseases associated with chemokine, e.g., CCR2 and/or CCR5, activity, such as atherosclerosis, restenosis, lupus, organ transplant rejection and rheumatoid arthritis.
Patent EA-007631-B1 (EA)
Title: Composition and method for treating a subterranean formation
Inventor: FRENIER WAYNE
IPC: E21B43/25
Filed: 2004-04-20
Abstract: An aqueous oilfield treatment fluid containing a chelating agent and an HF source is described. This fluid is effective at dissolving siliceous materials such as clays and keeping the dissolved materials in solution. In particular it is effective at preventing re-precipitation of initially-dissolved silicon as silica and therefore reduces damage to sandstones with which it is contacted. Methods are given for using this fluid for sandstone matrix stimulation, removal of clay-containing drilling fluid components and filter cakes from wellbores, sandstone acid fracturing, and gravel pack and proppant pack cleaning.
Patent EA-009564-B1 (EA)
Title: Gaming machine
Inventor: SATO YASUYOKI
IPC: A63F13/00
Filed: 2005-11-30
Abstract: One embodiment of the present invention is a gaming machine having a credit-value/bet-value processor storing the number of beis paid out by a player, a stage information generator determining CPU-side dice-numbers for the gaming machine, a player-side dice determination device determining player-side dice-numbers for the player, and a stage win and loss determination device making comparison between the CPU-side dice-numbers and the player-side dice-numbers for determining a win and loss of the relevant stage, whereby from among a plurality of stages, a stage available for the player to play is determined depending on the number of bets stored in the credit/bet value processor.
Patent EA-010300-B1 (EA)
Title: Novel azabicyclic derivatives, a method of producing thereof and pharmaceutical compositions containing them
Inventor: CASARA PATRICK
IPC: A61P25/00
Filed: 2005-02-18
Abstract: The invention relates to a compound of the formula (I):wherein m and n, which may be identical or different, each one represents an integer from 0 to 2 inclusive, with the sum of the two integers being from 2 to 3 inclusive, p and q, which may be identical or different, each one represents an integer from 0 to 2 inclusive, Alk represents an alkylene, X represents an oxygen atom or an -N(R)- group wherein R represents a hydrogen atom, Y, Y' and W are as defined in the description, to its enantiomers, diastereoisomers, and also to the salts thereof with one or more pharmaceutically acceptable acid or base. The invention also relates to the method of producing thereof, pharmaceutical compositions containing them and to use of said compositions in medicine.
Patent EA-013746-B1 (EA)
Title: Combined use of metconazole and epoxiconazole for reducing or preventing the contamination of cereals with mycotoxins
Inventor: SEMAR MARTIN
IPC: A01N43/653
Filed: 2006-07-17
Abstract: The invention relates to the combined use of metconazole and epoxiconazole for reducing or preventing the contamination of cereals with mycotoxins formed by mould fungus producing trichothecene.
Patent EA-013174-B1 (EA)
Title: A device, a method and an apparatus for lifting a railway rail
Inventor: BOINTON RICHARD
IPC: E01B29/22
Filed: 2006-07-07
Abstract: The present invention relates to a device for lifting a railway rail and comprises an arm (105) which is operable to be rotated and a roller (110) mounted to the arm (105) with the possibility of rotation and pushing the roller with a lifting force. The fastening means is made with the possibility of detachable fixing the device to a rail fastening assembly.
Patent EA-014681-B1 (EA)
Title: Hump brake shoe
Inventor: TEMNIKOV FEDOR SERAFIMOVICH
IPC: B61H7/10
Filed: 2009-06-05
Abstract: The invention relates to railway transport. A hump brake shoe comprises a stop with a lever and a skid. The stop with the lever and the skid are made of antifriction material or other material, but in that case there are antifriction linings on the wheel rolling surfaces, having in pair with wheel material a low friction factor. In the skid lower part a slot is made accommodating a friction lining, having in pair with rail material a high friction factor. In the stop top part a vessel for liquid to be fed, via wick, onto the wheel rolling surface is accommodated. The hump brake shoe can be made of the material selected from the series: steel, duraluminium, metal alloys, polymers, composites. The antifriction linings are made of the material selected from the series: metal alloys, polymers, composites, having in pair with the wheel material the low friction factor – 0.01-0.10. The friction lining is made of a “ferado” strip or other composites, having in pair with the rail material the high friction factor – 0.35-0.50. In the vessel for liquid water or non-freezing liquid are placed. The invention provides a new technical result, that is in braking a wheel pair and the whole car to a complete stop, while keeping the wheels turning when running over the shoe, that prevents the wheel and rails damage during railway rolling stock maneuvers, especially in shunting humps of the railway stations. In addition, the shoe does not produce sparking and can be used in the shunting operation with discharge and fluid cargoes.
Patent EA-015852-B1 (EA)
Title: Air control regulator for combustion chamber
Inventor: KENDALL MARK W
IPC: F23N1/02
Filed: 2008-04-11
Abstract: An air control regulator regulates the amount of air flowing into the inlet of a combustion chamber by causing flowing air to support a disc located in the air passage against the force of gravity. Air passes around the edges of the disc and is channeled into a plurality of airflows by ovoid depressions in the inner surfaces of the regulator forming a venturi chamber. By regulating the airflow into the combustion chamber, combustion efficiency is improved.
Patent EA-019806-B1 (EA)
Title: Pleuromutilin derivatives and their use as antimicrobials
Inventor: THIRRING KLAUS
IPC: A61K31/16
Filed: 2008-07-11
Abstract: A compound of formula (I) or of formula (II) wherein X is oxygen or sulfur, and Y is a residue of pipecolic acid or a residue of an amino acid, preferably a naturally occurring amino acid.
Patent EA-029777-B1 (EA)
Title: Barley and malt-derived beverages with low dms level
Inventor: KNUDSEN SOEREN
IPC: A01H5/10
Filed: 2009-12-01
Abstract: The invention provides barley-derived beverages characterized by notably reduced levels of dimethyl sulfide (DMS) and/or its precursor S-methyl-L-methionine (SMM), or lacking said compounds. In addition, the invention relates to methods for producing the above-mentioned beverages and also to barley plants useful in the preparation of such beverages, as well as other plant products prepared from said plants. Utilization of the invention clears the way for making improved production procedures of beverages with improved taste profiles, and promises also for notable reductions in the thermal energy input for production of beer.
Patent EA-023939-B1 (EA)
Title: Leaded glass window with steel sections
Inventor: ASHIMOV KAIRAT ASHIMOVICH
IPC: E06B7/28
Filed: 2012-05-29
Abstract: Disclosed is a leaded glass window with steel sections used in civil engineering. The technical result attained by the invention is a leaded glass window with steel sections that is cheaper than similar leaded glass windows, has longer lifetime than windows with reinforced plastic sections, provides the possibility of mounting thicker glazing units with better sound and heat insulation; due to strength of steel sections, the window can be mounted at a higher level from the ground. This is achieved by provision of a leaded glass window comprising steel sections, a glazing unit, window hardware, a sandwich panel, a support section, an impost, a sash fixing section, rubber seals, jambs, cant boards, moulding, lamination, an insect screen, the steel sections being made of ferrous or galvanised metal and comprise a framework and two frames, inner and outer. The outer frame is joined to the framework by electric arc welding, and the inner frame is fastened to the casing by screw nails.
Patent EA-023978-B1 (EA)
Title: Bridge structure
Inventor: SHKLYAR VLADIMIR KHAIMOVICH
IPC: E01D1/00
Filed: 2012-07-17
Abstract: The invention is related to civil engineering, in particular, to bridge construction, and more particularly, to design of continuous-frame and continuous-girder reinforced concrete bridges. The invented bridge structure that can be built without scaffolds and that has span girders joint in the zone of minimum bending moments and lower transverse forces comprises end piers, N intermediate piers where N≥1, and a continuous girder span structure, precast with cast-in-place concrete, consisting of non-detachably linked girders. The girder of the first span is supported by the end pier and by the first intermediate pier with formation of a cantilever, and each next girder is mounted on the cantilever of the girder of the previous span and on the respective intermediate pier with formation of a cantilever, each girder on its ends, except the ends to be mounted on the end piers, having metal support tables for mutual supporting at the place of non-detachable joint of adjacent girders. The girders may be rigidly connected with respective piers to form a continuous-frame bridge structure, or they may be mounted on respective piers on hinged support parts to form a continuous-girder bridge structure.
Patent EA-023696-B1 (EA)
Title: Pesticide composition comprising fosetyl-aluminium, propamocarb-hcl and an insecticide active substance
Inventor: HUNGENBERG HEIKE
IPC: A01P7/04
Filed: 2007-12-21
Abstract: The present invention relates to the field of agrochemistry. The aim of the present invention is to provide a pesticide composition with improved characteristics, intended for protecting plants, crops or seeds against damaging insects. The essence of the present invention is a pesticide composition comprising: A) compounds: A1) fosetyl-Al, A2) propamocarb-HCl, in a A1/A2 weight ratio ranging from 1/12 to 12/1, and B) an insecticide compound rynaxypyr; in an A/B weight ratio ranging from 1/1,000 to 1,000/1, and a corresponding method of treatment using said composition.
Patent EA-022663-B1 (EA)
Title: Aerosol generator including multi-component wick
Inventor: YANG ZUYIN
IPC: A61M11/04
Filed: 2010-10-11
Abstract: An aerosol generator includes a composite conduit (1, 2, 3, 4) to transport multiple liquids (5, 6) to a heating element (7) at flow rates such that the liquids arrive at the heating element in desirable concentrations. The heating element volatilizes the liquids to form volatilized fluid, which mixes with ambient air to form an aerosol with desirable concentrations of the multiple liquids.
Patent EA-026046-B1 (EA)
Title: Method for loading loose bulky goods into a gondola car using a flexible insert, and an auxiliary frame for implementing the same
Inventor: ERUKAEV VIKTOR ANATOLIEVICH
IPC: B65G67/06
Filed: 2013-12-04
Abstract: The invention proposes an auxiliary frame (Fig. 1) for loading loose bulky goods into a gondola car using a flexible insert (Fig. 4) provided with loading chutes (2) on its top part, the method including the following: loading chutes are fixed to the auxiliary frame (Fig. 1) on a platform outside the car, after which the auxiliary frame (Fig. 1) together with the flexible insert (Fig. 4) attached to it through at least the loading chutes (2) is installed on sides of a gondola car body (11), the flexible insert (Fig. 4) being placed inside the gondola car body (11); bulky goods are charged inside the flexible insert (Fig. 4) through loading chutes (2), after which the loading chutes (2) are detached from the auxiliary frame (Fig. 1), then the auxiliary frame (1) is removed from the gondola car body (11), and the loading chutes (2) are tightly closed. The auxiliary frame (Fig. 1) comprises a support frame (3) of a rectangular shape having a distance between its longitudinal bars corresponding to the distance between longitudinal sides of the gondola car body (11); loading necks the number of which corresponds to the number of loading chutes (2) of the flexible insert (Fig. 4), the loading necks being mounted on the support frame (3) in one row along its central longitudinal axis by means of supporting elements, the distances between vertical axes of the loading necks corresponding to distances between vertical axes of the loading chutes (2) of the flexible insert (Fig. 4); and fixing elements (6) arranged on the support part to prevent its shifting relative to the sides of the gondola car body (11), respectively. The invention allows an increase in labour productiveness, reduction of costs of the loading work, and reduction of loading downtime of gondola cars.
Patent EA-024894-B1 (EA)
Title: Apparatus for recovering draw solutes
Inventor: MCGINNIS ROBERT
IPC: B01D61/10
Filed: 2011-09-21
Abstract: The present invention relates to an apparatus for recovering draw solutes using an osmotically driven membrane system. Draw solute recovery may be carried out by various means including the use of distillation columns and/or membranes, where the recovery may be assisted by a heat pump.
Patent EA-026995-B1 (EA)
Title: Method for ascertaining the fertilizer requirement, in particular the nitrogen fertilizer requirement, and apparatus for carrying out the method
Inventor: MAIDL FRANZ-XAVER
IPC: A01C21/00
Filed: 2012-03-02
Abstract: A method and a device for discharging fertilizer for agricultural cultivated plants are disclosed. According to the invention, the required quantity of fertilizer is determined depending on the current nutrient uptake (nutrient status), optimum nutrient uptake (nutrient requirement) by the fertilizing deadline, and optimum nutrient uptake (nutrient requirement) by the next fertilizing deadline, wherein other influencing factors are taken into consideration via a correction factor DIMA.
Patent EA-024064-B1 (EA)
Title: Tire tread for a farm tractor
Inventor: VERVAET PATRICK
IPC: B60C11/11
Filed: 2012-05-22
Abstract: The present invention relates to a tire for a farm vehicle, specifically to the tread of such a tire. The aim of the invention is to reduce the stresses on the front surfaces of the tread bars, located on the axially outer ends thereof, due to the residual harvested stubble, thus to reduce the risk of tearing of the axially outer ends of the bars. Said aim was achieved by a tire including a tread that includes a plurality of bars, wherein one bar (3) includes, in every axial plane (P) parallel to the rotational axis of the tire, a leading profile (311) and a trailing profile (321). According to the invention, the angle (A) of the straight line (T) tangential to the leading profile (311), at one point (M) of the leading profile (311) and in relation to an equatorial plane (P), continuously increases, from a point (E) located most axially outside the leading profile (311), when the axial distance (L) between the point (M) of the leading profile and the point (E) located most axially outside the leading profile (311) increases. The angle (A) reaches a maximum value (A) at a point of inflexion (I) of the leading profile (311), and the radius of curvature (R) at every point (M) on the leading profile (311), which is axially positioned between the point (E) located most axially outside and the point of inflexion (I), is at least equal to 0.4 times the height of the bar.
Patent EA-027770-B1 (EA)
Title: USE OF INHIBITOR OR Wnt/β-CATENIN MECHANISM FOR TREATMENT OR PREVENTION OF A DISEASE AND DISORDER RELATED TO TRANSDUCIN β-LIKE PROTEIN 1 (TBL1) ACTIVITY, INCLUDING MYELOPROLIFERATIVE NEOPLASIA OR CHRONIC MYELOID LEUKEMIA
Inventor: BHALLA KAPIL N
IPC: C07C225/34
Filed: 2012-11-06
Abstract: The present invention relates to the use of a compoundhaving structure for the treatment or prevention of myeloproliferative neoplasia, in particular chronic myeloid leukemia. The compound of the present invention interrupts the Wnt/β-catenin pathway and inhibits the deregulated activity of this pathway that is necessary for the treatment of β-catenin metabolism-related disorders, as well as inhibits transducin β-like protein 1 (TBL1) interaction with the molecule β-catenin.