baber/WOPTO huggingface dataset:
Patent CA-3009428-A1 (CA)
Inventor: AMBERG WILHELM
IPC: C07D413/12
Filed: 2016-12-22
Abstract: L'invention concerne des composés (hétéro)cycliques en tant que modulateurs de S1P, des compositions pharmaceutiques les contenant, et leurs utilisations dans le traitement, le soulagement ou la prévention des maladies ou des troubles médiés par un récepteur S1P.
Patent CA-3010139-A1 (CA)
Title: Melanges fongicides synergiques pour la lutte fongicide contre la piriculariose du riz
Inventor: MATHIESON JOHN T
IPC: A01N43/56
Filed: 2016-12-22
Abstract: La présente invention concerne une composition fongicide contenant une quantité efficace sur le plan fongicide de tricyclazole ; et au moins un fongicide sélectionné dans le groupe constitué du benzovindiflupyr et du fluxapyroxade. Ladite composition permet une lutte synergique contre certains champignons.
Patent CA-3010379-A1 (CA)
Title: Ceramic-based toughness-enhanced material based on single crystal sapphire fiber and preparation method therefor
Inventor: LIU RENCHEN
IPC: C04B35/80
Filed: 2018-05-16
Abstract: A ceramic-based toughness-enhanced material comprises the following starting materials by volume percentage: 92-96%ceramic substrate powder, 2-4%single crystal sapphire fiber, 0.3-0.4%ceramic substrate disperser, 0.6-0.7%single crystal sapphire fiber disperser and 3-5%sintering aid. By controlling a suitable addition ratio, the strength of the single crystal sapphire fiber-enhanced ceramic substrate material is subject to tiny impacts, and the toughness of the ceramic substrate material is improved as much as possible that has a bright application prospect. In addition, single crystal sapphire fiber has a good compatibility with ceramic substrate that prevented the agglomeration and ensured the improvement of the toughness.
Patent CA-3012508-A1 (CA)
Title: Combined use of at least one endo-protease and at least one exo-protease in an ssf process for improving ethanol yield
Inventor: LI MING
IPC: C12P7/06
Filed: 2017-03-01
Abstract: Improved processes for producing ethanol from starch-containing materials by the combined use of at least one endo-protease and at least one exo-protease in an SSF process are disclosed. More particularly the exo-protease should make up at least 5% (w/w) of the protease mixture.
Patent CA-3012846-A1 (CA)
Title: Max binders as myc modulators and uses thereof
Inventor: EVANS HELEN L
IPC: A61P35/00
Filed: 2017-02-16
Abstract: The present disclosure provides compounds of Formula (I'), Formula (I), Formula (II), Formula (II-A), Formula (III), and Formula (IV). The compounds described herein are MAX binders and/or modulators of Myc, Mad, or Mxil (e.g., inhibitors of Myc, Mad, or Mxil), and may be useful in treating a subject with a disease associated with Myc, such as proliferative diseases ( e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions and kits including the compounds described herein, as well as methods of using and uses of the compounds, compositions, and kits.
Patent CA-3013534-A1 (CA)
Inventor: LOKKINEN MIKA
IPC: A46D1/00
Filed: 2017-02-02
Abstract: L'invention se rapporte à un dispositif de revêtement qui comprend une broche rotative (10) qui comporte des moyens de fixation (14) destinés à fixer un axe de rotation à la broche (10). Il comprend également des saillies (12b) qui font radialement saillie depuis la broche (10) pour étaler la substance de revêtement sur la surface interne d'un tuyau. Les saillies (12b) sont des bandes flexibles et en forme de plaque qui s'enroulent autour de l'axe de leur côté le plus long de telle sorte que la section transversale de la saillie (12b), dans la direction de l'axe de rotation de la broche (10), soit la plus petite au niveau de l'extrémité la plus à l'extérieur. Les saillies (12b) comportent des limiteurs (13) qui limitent l'étalement de la substance de revêtement à l'épaisseur de couche souhaitée. L'invention se rapporte également à un système et à un procédé de revêtement.
Patent CA-3017821-A1 (CA)
Inventor: PEARSON GREGORY ALAN
IPC: B01J29/40
Filed: 2017-03-21
Abstract: L'invention concerne un catalyseur qui est destiné à être utilisé dans la conversion catalytique et thermique de biomasse et qui contient de l'alumine provenant de chlorohydrate d'aluminium, du kaolin phosphaté et une zéolite phosphatée calcinée ZSM-5. Le catalyseur peut être préparé en ajoutant une suspension de particules de la zéolite phosphatée calcinée ZSM-5 à l'acide phosphorique et au kaolin, puis en ajoutant le chlorohydrate d'aluminium au produit obtenu. Les particules sont ensuite séchées par pulvérisation et calcinées.
Patent CA-3019024-A1 (CA)
Inventor: HOCHSTOGER JURGEN
IPC: H01B7/02
Filed: 2017-03-20
Abstract: An insulated electric conductor and the method for producing it are described, the electric conductor having improved adhesion between conductor and insulating coating, wherein the insulating coating includes either at least one insulating layer made of thermoplastic material, or a plastic-containing intermediate layer, the electric conductor obtained by a method in which the electric conductor is placed under a protective gas atmosphere and is bombarded with ions of the protective gas in a gas plasma in order to remove an oxide layer formed on a surface of the electric conductor and/or to increase the surface energy of the electric conductor, and subsequently either the at least one insulating layer or, in the case that the coating comprises the plastic-containing intermediate layer, at least the plastic-containing intermediate layer is applied directly to the surface of the electric conductor (1) under a protective gas atmosphere.
Patent CA-3019765-A1 (CA)
Inventor: VANSICKLER MICHAEL T
IPC: G01N35/04
Filed: 2017-02-17
Abstract: Automated analyzer (2000) comprising a housing (2010, 3010), a robotic arm comprising an end effector (2360), the end effector (2360) comprising a body (2320) rotatably connected to an articulating arm and first (2363a) and second fingers (2363b) coupled to the body (2362) and being moveable relative to each other in a first direction, each of the fingers (2363a, b) having an engagement feature (2361) projecting inwardly from each of the first and second fingers (2363a, b) and toward the other of the first and second fingers (2363a, b), the engagement feature (2361) being configured to engage a recess (2077) of an article wherein the recess is configured to receive the engagement feature (2361) such that the robotic arm can carry the article that is suspended from the first and second fingers (2363a, b) when the engagement features (2361) are so engaged with the article. The automated analyzer (2000) further comprises a shuttle platform (2030) for receiving a shuttle (2030) carrying sample containers (03), the containers carrying sample (03) to be evaluated by the analyzer (2000) and the shuttle platform (2030) comprising a jaw assembly that automatically moves from an open position to a closed position the jaw assembly comprising engagement members that do not contact the bottom portion of the sample containers (03) carried by the shuttle (2030) when the jaw assembly is in an open position and engages the bottom portion of the sample containers when the jaw assembly is in the closed position.
Patent CA-3020640-A1 (CA)
Title: Neurotoxines chimeriques comprenant un domaine lhn d'une premiere neurotoxine liee a un domaine de chaine lourde d'une deuxieme neurotoxine et utilisation en therapie
Inventor: LIU SAI MAN
IPC: C07K14/33
Filed: 2017-05-05
Abstract: La présente invention concerne des neurotoxines chimériques comprenant un domaine LHn à partir d'une première neurotoxine liée à un domaine He d'une deuxième neurotoxine, dans lequel cas (a) le terminal-C dudit domaine LHn correspond au premier résidu d'acide aminé de l'helix 3io séparant les domaines LHn et He dans la première neurotoxine, (b) le terminal-N du domaine He correspond au deuxième résidu d'acide aminé de de l'helix 3io séparant les domaines LHn et He dans la deuxième neurotoxine et (c) la première et la deuxième neurotoxine est un sérotype A, sérotype B, sérotype C, sérotype D, sérotype E, sérotype F ou sérotype G de la neurotoxine botulique (BoNT) ou une neurotoxine de tétanos (TeNT) et la deuxième neurotoxine est un serotype A, B, C, D, E, F or G de BoNT ou une TeNT. Elle est également liée à l'utilisation de ces neurotoxines chimériques lors de thérapies.
Patent CA-3021846-A1 (CA)
Title: Compositions and methods for the treatment of lysosomal storage disorders and disorders characterized by lysosomal dysfunction
Inventor: SARDIELLO MARCO
IPC: C07H3/04
Filed: 2017-04-21
Abstract: The present invention relates to compositions and methods of treating lysosomal storage diseases and methods of using trehalose.
Patent CA-3025596-A1 (CA)
Inventor: DE JONG RENE MARCEL
IPC: C12N9/20
Filed: 2017-06-08
Abstract: The present invention relates to a polypeptide having lipase activity wherein the polypeptide, which, when aligned with a polypeptide according to SEQ ID NO: 1, comprises at least one amino acid substitution resulting in Ser (S), Ala (A) or Leu (L) at position 246, Trp (W) at position 307, Leu (L) at position 345, lie (I) at position 365, and / or Phe (F) at position 534, wherein the position is defined with reference to SEQ ID NO: 1, wherein Ala(A) at position 1 in SEQ ID NO: 1 is counted as number 1 and a method for preparing the polypeptide. The present invention further relates to a process for preparing a food product wherein a polypeptide according to the present invention is used.
Patent CA-3027048-A1 (CA)
Inventor: ASTUDILLO DE LA VEGA HORACIO
IPC: A61K9/10
Filed: 2017-06-08
Abstract: The invention relates to compounds of natural origin and to the pharmaceutically acceptable, active mixture thereof for the reduction of high levels of glucose, cholesterol, uric acid and body fat, cytoprotection of damaged organs, activation of the metabolism and cell proliferation. The invention is illustrated with the example of a pharmaceutical composition comprising a pharmaceutically effective quantity of the compounds of formulation I, and the method for using same in in vitro and in vivo systems. Formulation I and the variables thereof can be used to treat hyperglycemia, gout, dyslipidemia, obesity, insulin resistance, diabetes mellitus, diabetes insipidus, type 1 diabetes, type 2 diabetes, microvascular complications, macrovascular complications, lipid disorders, prediabetes, arrhythmias, myocardial infarction, renal and pancreatic complications, cardiovascular complications.
Patent CA-3027524-A1 (CA)
Title: Article catalytique a base de pgm et osc en combinaison
Inventor: GU YUNLONG
IPC: B01J23/89
Filed: 2017-05-04
Abstract: La présente divulgation concerne des matériaux catalytiques et des articles catalytiques formés à partir de ceux-ci. En particulier, les matériaux catalytiques selon la présente divulgation peuvent comprendre un composant de stockage d'oxygène constitué d'une solution solide d'au moins un métal du groupe du platine et d'au moins un oxyde métallique du groupe des terres rares. Dans un ou plusieurs modes de réalisation, les matériaux catalytiques peuvent comprendre une solution solide d'un métal du groupe du platine (p. ex., palladium) et d'un mélange d'oxydes métalliques (p. ex., oxyde de cérium/zircone).
Patent CA-3029013-A1 (CA)
Inventor: Grimm Lafe
IPC: B65G21/14
Filed: 2017-06-21
Abstract: Conveyor apparatus, systems and methods are provided. Some embodiments include pivot assemblies for folding a conveyor frame between transport and operational configurations. In some embodiments, one or more frame sections of the conveyor frame are sized to be received in a shipping container.
Patent CA-3031609-A1 (CA)
Title: Gh9 endoglucanase variants and polynucleotides encoding same
Inventor: NIELSEN JENS ERIK
IPC: C12N9/42
Filed: 2017-08-24
Abstract: The present invention relates to endoglucanase variants and methods for obtaining endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Patent CA-3032505-A1 (CA)
Inventor: MOONEY DAVID J
IPC: A61K9/16
Filed: 2017-08-02
Abstract: La présente invention concerne des procédés et des compositions pour induire une réponse immunitaire à un antigène, tel que des antigènes cancéreux et microbiens.
Patent CA-3032601-A1 (CA)
Inventor: LI XIAOPING
IPC: F21V23/06
Filed: 2019-02-04
Abstract: Light strip is disclosed, which comprises a light strip, wherein the light strip comprises a strip, a light source, a plug and an input line; the plug comprises an end surface, a left side surface, and a right side surface; a first light transmitting layer and a vacant portion, the first light transmitting layer is disposed above the vacant portion, the input line is connected to the left side surface or the right side surface of the plug. The input line is disposed on the left side surface or the right side surface of the plug according to the present disclosure. When it requires to extend the length of the light strips, the end surfaces of the light strips can be seamlessly connected without bending the input line, thus making the light strips easy to install and more beautiful in appearance.
Patent CA-3033249-A1 (CA)
Title: Composes d'indazole destines a etre utilises dans des lesions de tendon et/ou de ligament
Inventor: BURSULAYA BADRY
IPC: A61K31/416
Filed: 2017-09-21
Abstract: La présente invention porte sur un composé de formule (I) sous forme libre ou sous forme de sel pharmaceutiquement acceptable (I), sur un procédé pour la fabrication du composé de l'invention et sur ses utilisations thérapeutiques. La présente invention concerne en outre une combinaison d'agents pharmacologiquement actifs et une composition pharmaceutique.
Patent CA-3034764-A1 (CA)
Inventor: DE BUCK JEROEN
IPC: C12Q1/34
Filed: 2017-09-01
Abstract: The present disclosure relates to a method referred to herein as the "split trehalase assay biosensor" (also referred to herein as "STIGA") is based on the use of engineered E.coli trehalase to detect analytes such as antibodies in a sample. The trehalase is engineered in a way such that the enzyme is split into two inactive fragments (N-terminal fragment H and C-terminal fragment A) with antigens fused to both fragments. When bivalent antibodies react specifically with the fused antigens, two inactive trehalase fragments are brought in close proximity to restore the activity of trehalase. The restored trehalase will hydrolyze trehalose into two glucose molecules which can be measured using existing glucose detection methods such as glucometer, Benedict's reagent, or ACCU- CHEK AVIVA® glucose test strips.
Patent CA-3036006-A1 (CA)
Title: Detection de proximite utilisant des balises de localisation
Inventor: TYERS MARK
IPC: G06Q20/32
Filed: 2017-09-05
Abstract: L'invention concerne des dispositifs utilisateurs (1-4), lesquels sont chacun dotés d'une liaison de données (20) à un serveur distant (30) et d'un émetteur-récepteur de balise. Le dispositif (2) peut fonctionner pour transmettre activement des signaux de balise comprenant son code d'identification de balise unique pendant une période limitée. Pendant les transmissions actives par le dispositif (2), des dispositifs (1 & 3) se situent dans la portée des transmissions et peuvent être utilisés pour extraire le code d'identification de balise du dispositif de transmission (2) et déduire ainsi directement qu'ils sont à proximité du dispositif de transmission (2). Les dispositifs de réception (1, 3) communiquent avec le serveur (30) leur propre code d'identification de balise unique et le code d'identification de balise reçu du dispositif de transmission (2). En réponse, le serveur (30) communique les détails du dispositif de transmission (2) aux dispositifs de réception (1, 3) et les codes d'identification de balise des dispositifs de réception (1, 3) au dispositif de transmission (2). Le dispositif de transmission (2) est capable de déduire la proximité des dispositifs de réception (1, 3) sans que les dispositifs de réception (1, 3) ne transmettent de quelconques signaux de balise.
Patent CA-3039294-A1 (CA)
Title: Golf mat
Inventor: HOOPER MICHAEL
IPC: A63B69/36
Filed: 2017-10-04
Abstract: A golf mat that has a natural feel and mitigates injury during mat striking includes: a base, the base including a main structure with an upper surface and an open topped cavity in the upper surface; and an insert sized to be accommodated in the cavity, the insert including a layer of solid polymeric material selected to have shock absorption properties greater than the main structure; and artificial turf installed on the base and overlying at least a portion of the main structure and the insert.
Patent CA-3041641-A1 (CA)
Title: Bed with foot warming system
Inventor: KARSCHNIK KODY LEE
IPC: A61G7/05
Filed: 2017-10-24
Abstract: A bed can include a mattress and a foot warming system. The mattress can include a mattress cover and a support structure that is positioned under and covered by the mattress cover. The foot warming system can include a heating unit an envelope, a power source, and an electrical connector electrically connecting the heating unit to the power source. The heating unit can be positioned inside the envelope between the envelope top and the envelope bottom. The heating unit and the envelope can be positioned at a foot of the bed under mattress cover between the support structure and the mattress cover.
Patent CA-3042691-A1 (CA)
Inventor: ZHANG KANG
IPC: A61K31/7105
Filed: 2017-11-03
Abstract: L'invention concerne des procédés et des compositions pharmaceutiques pour le traitement de la rétinite pigmentaire, la dégénérescence maculaire et autres affections rétiniennes par interférence avec l'expression de gènes, tels que ceux codant pour le récepteur nucléaire spécifique à la cellule de photorécepteur et la protéine NRL - fermeture à glissière à leucine spécifique à la rétine neuronale -, dans des cellules de l'il. Ces méthodes et compositions font appel à des thérapies basées sur les acides nucléiques.
Patent CA-3043766-A1 (CA)
Title: Therapie du cancer du poumon a petites cellules (cppc) avec un conjugue anticorps-medicament (cam) inhibiteur de la topoisomerase i ciblant trop-2
Inventor: GOLDENBERG DAVID M
IPC: C07K16/30
Filed: 2018-02-21
Abstract: La présente invention concerne le traitement du CPPC avec des CAM comprenant un médicament lié à un anticorps anti-Trop-2 ou à un fragment d'anticorps se liant à l'antigène. De préférence, le médicament est SN-38. Plus préférablement, l'anticorps est un anticorps hRS7 et le CAM est le sacituzumab govitécan. LE CAM peut être administré à une dose comprise entre 4 mg/kg et 16 mg/kg, de préférence 4, 6, 8, 9, 10, 12 ou 16 mg/kg, de manière préférée entre toutes de 8 à 10 mg/kg. Lorsqu'il est administré à des dosages et des posologies spécifiés, le CAM peut réduire la taille de tumeurs solides, réduire ou éliminer les métastases et est efficace pour traiter les cancers résistant aux thérapies standards, telles que la radiothérapie, la chimiothérapie ou l'immunothérapie. De manière surprenante, le CAM est efficace pour traiter des cancers réfractaires à ou récidivant après traitement par l'irinotécan ou le topotécan. De préférence, le CAM est administré sous la forme d'une polythérapie avec un ou plusieurs autres traitements anticancéreux, tels que le carboplatine ou le cisplatine.
Patent CA-3043784-A1 (CA)
Title: Implant for osteosynthesis, and implant kit comprising an implant
Inventor: LEIBINGER CHRISTIAN
IPC: A61B17/86
Filed: 2017-12-11
Abstract: The invention relates to an implant (1) for osteosynthesis, comprising a securing region (3) that has a plurality of holes (2) for receiving securing means, and two projections (4) which extend away, at least partially curved, from said securing region (3), wherein at least one of the two projections (4) takes the form of a snap-on lug (5) that can snap onto a bone segment (7, 8) of a mammal bone (6); the invention also relates to an implant kit comprising such an implant (1).
Patent CA-3044300-A1 (CA)
Inventor: CLARK ROBERT J
IPC: E06B3/04
Filed: 2019-05-27
Abstract: A frame for a traffic door having a leading edge, trailing edge, top edge, and bottom edge. The frame includes a trailing edge frame member having first and second ends and configured to extend along the trailing edge of the traffic door. The trailing edge frame member is a monolithic body having a first portion and a second portion, wherein the first portion extends between the first and second ends in a continuous and linear manner. The trailing edge frame member further includes a first cutout from the second portion of the trailing edge frame member adjacent the first end and a second cutout from the second portion of the trailing edge frame member adjacent the second end to define a central tab. A traffic door having such a frame is disclosed. A  method of forming a traffic door with such a frame is also disclosed.
Patent CA-3047612-A1 (CA)
Inventor: SKOVBO CHRISTIAN
IPC: F24B1/02
Filed: 2017-12-18
Abstract: Disclosed is a stove (1) arranged for combusting granular material. The stove (1) comprises a granular material combustion area (5) including a bottom combustion surface (6) and granular material feeding means (15) arranged for feeding granular material up into the granular material combustion area (5) from a granular material storage (16) arranged beneath the granular material combustion area (5), wherein the granular material feeding means (15) comprises a curving auger (21). Furthermore, a use of a stove (1) is disclosed.
Patent CA-3053223-A1 (CA)
Inventor: BENADIKOVA DANIELA
IPC: C07D279/18
Filed: 2018-03-15
Abstract: The present invention relates to: a process for preparing 3,7-bis-(dimethylamino)-phenothiazin-5- ium bromide or chloride; a method of converting 3,7-bis-(dimethylamino)-phenothiazin-5-ium bromide to 3,7-bis-(dimethylamino)-phenothiazin-5-ium chloride; and the purification of 7-bis- (dimethylamino)-phenothiazin-5-ium chloride by crystallization from aqueous solution of hydrochloric acid, leading to a pharmaceutically acceptable 3,7-bis-(dimethylamino)-phenothiazin- 5-ium chloride (methylthioninium chloride, methylene blue, MTC) of formula I below reported.
Patent CA-3054548-A1 (CA)
Title: Lin a teneur elevee en acide linolenique
Inventor: GOLAS NATHAN
IPC: A01H6/58
Filed: 2017-02-27
Abstract: La présente invention concerne un cultivar simple de la plante de lin (Linum usitatissimum) qui produit un nouveau profil d'acide linolénique. L'invention concerne également la plante, les produits huileux et les gènes uniques du cultivar. Il est en outre décrit un cultivar produisant une graine contenant une concentration élevée en acide alpha-linolénique par un profil de génome comprenant un ADNc et des régions de répétition de séquence simple (SSR ou microsatellite). Le cultivar peut également être identifié par son nouveau profil d'huile de lin.
Patent CA-3055709-A1 (CA)
Title: Providing promotions on mobile gaming devices
Inventor: LUTNICK HOWARD W
IPC: G07F17/32
Filed: 2007-12-06
Abstract: Promotions are provided on a mobile gaming device. A mobile gaming used by a player may be identified. A promotion may be provided to the mobile gaming device. The promotion may include at least one of video and audio. A wireless based signal is received from the mobile gaming device. The mobile gaming device is operable to allow a player of the mobile gaming device to gamble. A promotion is outputted to the player, based at least in part on receiving the wireless based signal. The promotion has video and/or audio.
Patent CA-3055810-A1 (CA)
Inventor: BLANDEN ADAM
IPC: C07K14/195
Filed: 2018-03-07
Abstract: Disclosed herein are compositions, methods, and systems for the purification and/or detection of recombinant and other proteins. In some embodiments, compositions may comprise recombinant protein with one or more sequences having substantial homology to RP-Tag Small or RP-Tag Large. In some cases, the disclosed compositions may be useful in binding or recognizing target proteins.