baber/WOPTO huggingface dataset:
Patent EP-1392289-A2 (EP)
Inventor: MORTIMORE MICHAEL
IPC: A61P31/04
Filed: 2002-05-23
Abstract: L'invention concerne des composés de formule I, dans laquelle Z représente oxygène ou soufre; R1 représente hydrogène, -CHN¿2?, R, CH2OR, CH2SR ou -CH2Y; --- à côté de R?3¿ représente une liaison simple ou double; Y représente un groupe partant électronégatif; R2 représente CO¿2?H, CH2CO2H ou des esters, des amides ou des isostères de celui-ci; R?3¿ représente un groupe pouvant se raccorder dans le sous-site S2 d'une enzyme caspase; R4 représente hydrogène ou alkyle C¿1-6? ou R?3 et R4¿ pris ensemble forment un cycle; le cycle A et le cycle B sont tout deux des anneaux hétérocycliques et R et R5 sont tels que définis dans la description. Les composés selon l'invention sont des inhibiteurs efficaces de l'apoptose et de la sécrétion d'IL-1β.
Patent EP-1397068-A2 (EP)
Inventor: DRUCKER STEVEN
IPC: G16H10/60
Filed: 2002-03-29
Abstract: A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present in a sample of body fluid, when the test strip is positioned in the receptacle and the body fluid is placed on a test strip, and communicate the glucose amount to the hand-held computer via the connector portion.
Patent EP-1401565-A2 (EP)
Inventor: AUSTIN KYLE P
IPC: B01J38/10
Filed: 2002-06-19
Abstract: A reactor and regeneration for effecting radial flow contact of a reactant stream with catalyst particles movable as an annular-form bed by gravity flow and for reducing stresses in the bed is disclosed.
Patent EP-1428114-A2 (EP)
Inventor: CAI HONG
IPC: G06F17/30
Filed: 2002-07-08
Abstract: Disclosed is a method and device for keeping persistency while switching between modalities, which include: (1) searching out the last operation state of the application service accessed by the user from the user history , in response to a request for accessing an application service from a user; (2) connecting to the application service and continuing to execute the application service from the last operation state; (3) updating the last operation state in the user history based on the execution result of the application service. A user could flexibly selects different favorable terminal to continue with unfinished application service by adopting the invention.
Patent EP-1414955-A2 (EP)
Inventor: ADLER KARL EDWIN JR
IPC: C12Q1/28
Filed: 2002-06-28
Abstract: A method for enhancing the conversion of a phenol substrate to a product by a peroxidase enzyme comprises the steps of reacting a conjugate comprising a detectably labeled phenol-containing molecule with a peroxidase enzyme in the presence of an enhancing reagent, the enhancing reagent comprising an organic compound having the structurewherein each R is independently selected from the group consisting of: hydrogen and a C1-12 substituent; where V, W, Y and Z are each independently selected from the group consisting of: H, halogen, the C1-12 substituent, NR2, OR and SR; and where X is selected from the group consisting of: H, Br, Cl, F, the C1-12 substituent, NR2, OR and SR; or synergistic mixtures of an inorganic salt and the organic compound. The C1-12 substituent is linear, branched or cyclic. The C1-12 substituent is alkyl, alkenyl, alkynyl, heteroatom substituted alkyl, heteroatom substituted alkenyl, heteroatom substituted alkynyl, aryl, arylalkyl, arylalkenyl or arylalkynyl. Further, the heteroatom is N, O, S or halogen. Any C, N, O or S in the C1-12 substituent optionally has a pendant moiety which is carbonyl, hydroxyl, carboxyl, amine, thiol, thioester, thioether, phosphate, alkoxy, aryl, arylalkyl, sulfonamide or alkyl halide. A kit is provided containing an enhancing reagent for enhancing the detection of an enzyme reaction as described herein, together with instructions for use.
Patent EP-1412065-A2 (EP)
Title: Appareil et procedes de melange de flux laminaires
Inventor: STROOCK ABRAHAM D
IPC: B01F5/00
Filed: 2002-07-24
Abstract: L'invention concerne un appareil de mélange utilisé afin de réaliser le mélange d'un ou de plusieurs flux de fluides. Cet appareil fonctionne généralement par création d'un composant d'écoulement transversal au fluide s'écoulant dans un canal sans utiliser d'éléments mobiles de mélange. Le composant d'écoulement hélicoïdal ou transversal du ou des fluides en mouvement est créé par de faibles modulations de la forme des parois du canal. Le composant d'écoulement hélicoïdal ou transversal peut être aussi créé par des caractéristiques de rainures définies sur la paroi du canal. La présente invention peut être spécifiquement utilisée avec des fluides à écoulement laminaire. Cet appareil et ces procédés de mélange permettent de réaliser le mélange d'un ou de plusieurs fluides possédant un nombre de Reynolds inférieur à 100 environ. La présente invention peut ainsi être utilisée afin de mélanger un fluide s'écoulant en micro-régime. L'appareil de mélange peut être utilisé pour mélanger un fluide dans un système microfluidique afin de réduire de manière importante la dispersion de Taylor le long de la direction principale. Il peut être encore utilisé afin d'augmenter la zone effective exposée afin de promouvoir la diffusion de composants dans un fluide ou entre plusieurs fluides.
Patent EP-1455672-A2 (EP)
Inventor: TORCHIA MARK G
IPC: A61B19/00
Filed: 2002-12-12
Abstract: An MRI guided surgical apparatus includes a heat source formed by a laser and an optical fiber carrying the heat energy into a part to be coagulated by hyperthermia with an end reflector to direct the energy in a beam to one side of the fiber end. A reinforcing sleeve for the fiber is mounted in a shielded, Piezo-electric motor which causes movement of the fiber longitudinally and angularly within a rigid elongate cannula. A magnetic resonance imaging system is arranged to generate a series of output signals over a period of time representative of temperature in the part as the temperature of the part changes during that time. The heat source is controlled in heat energy applied and location and orientation of the beam to stop heating when the temperature at the boundary of a tumor reaches the required hyperthermic temperature. Cooling of the tip portion of the probe is effected by expansion of a supplied cooling fluid in gaseous form through a restrictive orifice into an expansion zone at the probe end. The fiber is thus encased in a stiff tubular titanium probe with a relatively small fluid supply duct along the inside of the probe with the interior of the probe acting as a return duct for the expanded gas. Thus the fiber end is contained in gas rather than liquid and the temperature of the probe end can be monitored by a sensor in the probe end and controlled by controlling the pressure in the supplied cooling fluid. The probe is driven in the longitudinal and rotational directions to move the fiber tip.
Patent EP-1420996-A2 (EP)
Inventor: SVARTZ BJORN O
IPC: B60G11/27
Filed: 2002-08-16
Abstract: In an over the highway vehicle, a frame including a pair of elongate frame rails and a plurality of cross members is disclosed. One of the rails includes an integrally formed bracket projecting laterally. The bracket is adjacent a rail aperture formed by cutting the one rail to define the bracket and after such cutting bending the bracket out of a plane of the one rail.
Patent EP-1456727-A2 (EP)
Inventor: KAHLER ARNE
IPC: G05D23/19
Filed: 2002-12-17
Abstract: The invention relates to a method for adapting the thermal output in heating installations (2) by using a thermal output control (7) of the heating installation (2), particularly by varying the flow temperature (ÑHVL) and/or mass flow (.m), and to a corresponding device. The aim of the invention is to adapt the thermal output better to the actual heat demand. To this end, a supply state control, in particular, a supply state adaptation module (6) is provided, whereby a heating circuit state or building supply state (BST) that takes the heat demand of the rooms into account and serves as a control variable is compared with a predeterminable set value for the heating circuit state or building supply state (BSTS), and a set value (VLTS) and/or correction value (DELTAVLT) for the thermal output control (7) is determined from this comparison.
Patent EP-1463714-A2 (EP)
Inventor: BO YUNXIN Y
IPC: C07D241/42
Filed: 2002-12-10
Abstract: La présente invention concerne des composés représentés par la structure générale de la formule (1) et des compositions contenant ces composés, destinés au traitement de douleurs neurogènes et inflammatoires aiguës, de douleurs dentaires, de céphalées générales, de la migraine, de la céphalée vasculaire de Horton, des syndromes vasculaires mélangés et des syndromes non vasculaires, de la céphalée par tension psychique, de l'arthrite à inflammation générale, de maladies rhumatismales, de l'arthrose, de troubles intestinaux inflammatoires, de troubles oculaires inflammatoires, de troubles de la vessie instables ou inflammatoires, du psoriasis, de problèmes cutanés à composantes inflammatoires, de pathologies inflammatoires chroniques, de douleurs inflammatoires et de l'hyperalgie et de l'allodynie associées, de douleurs de neuropathie et de l'hyperalgie et de l'allodynie associées, de douleurs neurogènes diabétiques, de la causalgie, de douleurs continues sympathiques, des syndromes de désafférentation, de l'asthme, de la dégradation ou du dysfonctionnement de tissu épithélial, de l'herpès, de perturbations de la motilité viscérale dans les régions du système respiratoire, génito-urinaire, gastro-intestinal ou vasculaire, de blessures, de brûlures, de réactions cutanées allergiques, du prurit, du vitiligo, de troubles généraux du tube digestif, de l'ulcère gastrique, des ulcères duodénaux, de la diarrhée, des lésions gastriques induites par des agents nécrosants, de la croissance capillaire, de la rhinite vasomotrice ou allergique, de troubles bronchitiques ou de troubles de la vessie.
Patent EP-1430163-A2 (EP)
Inventor: HAHNDORF INA
IPC: B01D61/14
Filed: 2002-08-15
Abstract: Various methods have been proposed to separate precious metal from a fluid utilized for plating. The known methods and devices are complicated and expensive. To overcome this problem, a method and a device for plating work pieces with a fluid containing at least one precious metal are provided. According to the invention the work pieces are contacted with the fluid and the fluid is filtered, after use, through at least one ceramic membrane filter in order to separate the at least one precious metal from the fluid. According to the invention a ceramic membrane filter having an exclusion pore size in excess of 10,000 Dalton is utilized.
Patent EP-1444782-A2 (EP)
Inventor: SCHENK JOACHIM
IPC: H03K17/695
Filed: 2002-10-22
Abstract: A device for controlling at least one electrical load and a control device therefor. The electrical load includes a first load connection and a second load connection. The first load connection is able to be connected to an operating-voltage potential via a first controlled switch, and the second load connection is able to be connected to a reference voltage potential via a second controlled switch.
Patent EP-1412535-A2 (EP)
Inventor: BROWN PATRICK O
IPC: C12M1/34
Filed: 2002-07-02
Abstract: On établit le profil de cellules par rapport à leur expression de molécules de surface de cellule et à leur capacité de répondre à un stimulus externe dans un micro-environnement. Des stimuli externes incluent des interactions cellule-cellule, une réponse à des facteurs et d'autres phénomènes similaires. Ces cellules sont ordonnées sur un substrat plan ou en trois dimensions par des liaisons à des sondes immobilisées ou partiellement diffusée. Des sondes intéressantes comprennent des partenaires de liaison spécifiques de molécules de surface de cellule, qui signalent des indices agissant pour réguler des réponses cellulaires, des facteurs de différentiation etc., et qui peuvent être ordonnés comme une molécule ou une combinaison de molécules.
Patent EP-1465631-A2 (EP)
Inventor: CASTELHANO ARLINDO
IPC: C07D471/10
Filed: 2002-12-20
Abstract: The subject invention provides compounds having the structure: wherein R1 is substituted or unsubstituted phenyl or a 5-6 membered heterocyclic or heteroaromatic ring containing from 1 to 5 heteroatoms; R2 is hydrogen, or a substituted or unsubstituted alkyl, -C(O)-alkyl, -C(O)-O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety; R3 is hydrogen, or a substituted or unsubstituted alkyl, -C(O)-alkyl, -C(O)-O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety, or R2 and R3 are joined to form a heterocyclic ring; wherein the dashed line represents a second bond which may be present or absent, and when present R3 is oxygen; R4 and R5 are each independently substituted or unsubstituted alkyl, -C(O)-alkyl, -C(O)-O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety, or R4NR5 together form a substituted or unsubstituted monocyclic or bicyclic, heterocyclic or heteroaryl moiety containing from 1 to 6 heteroatoms; R12 is hydrogen, alkyl, halogen or cyano; and n is 0, 1, 2, 3 or 4, or an enantiomer, or a specific tautomer, or a pharmaceutically acceptable salt thereof and a method for treating a disease associated with the A2b adenosine receptor by administering a therapeutically effective amount of the compounds of the invention.
Patent EP-1376760-A2 (EP)
Inventor: ZIMMERMANN MARTIN L
IPC: H01Q1/48
Filed: 2003-02-27
Abstract: A single piece twin folded dipole antenna for
transmitting and receiving electromagnetic signals is
provided. The antenna includes a conductor extending in a
V-shape at an angle of approximately 45 degrees adjacent to
a ground plane. The conductor includes a feed section, a
radiator input portion, and a radiating portion. The
radiator input portion includes a first radiator input
section and a second radiator input section whereby the
radiator input sections are integrally formed with the
radiating portion. The radiating portion includes a first
radiating section and a second radiating section connected
in parallel whereby each radiating section includes a fed
dipole and a passive dipole.
Patent EP-1344874-A2 (EP)
Inventor: BRAENDSTROEM LARS
IPC: E03F5/04
Filed: 2003-03-07
Abstract: Methods and devices for building-in
a gully, consisting of a gully member (1) and an extension
ring member (2), into a floor or roof.
The methods are characterized by a first construction step
during which an eventual extension
ring member (2) is held temporarily fixed to the
gully member (1) in a first position in which flanges
(9 and 6), by adjusting the extension ring member (2)
to a second position in which its flange (9)
extends horizontally and flush
with the future top surface of the floor or roof structure,
and by a second construction
step during which the extension ring member (2)
is held temporarily fixed to the gully member (1) in
said horizontal position until the extension ring member
(2) is finally fixed therein with the flange (9) flush
with the top surface of the floor or roof structure. 
     The devices comprise to this end one, alternatively two
fixing means (26;26,27).
Patent EP-1538506-A2 (EP)
Inventor: LOUKIPOUDIS EVGUENI
IPC: G06Q10/00
Filed: 2003-12-05
Abstract: A system and a method are described for accessing, according to selection criteria
and security rules, secure information from a set of secret data, mainly in a medical
system for patient data. A performance problem arises when applying the security
rules first, followed by the selection criteria. A solution is to perform the selection
step first, followed by application of the security rules. The method may be used in
a computer or server system e.g. for scheduling examinations of patients in a
radiology department or for documentation purposes of these examinations.
Patent EP-1362680-A2 (EP)
Inventor: JARDINE MARK HAMILTON
IPC: B28B7/00
Filed: 2003-05-12
Abstract: This invention relates to prestressed concrete units, to a
method of manufacture of prestressed concrete units and to a
mould system for use in such a method. The invention provides
a method of manufacturing a prestressed concrete unit using a
mould system comprising an elongate mould containing at least
one prestressed element and an elongate hopper having an
aperture, comprising the steps of locating at least one
reinforcing element in a substantially perpendicular
orientation to said mould; filling the elongate mould with
concrete to form a first portion of the unit; locating the
hopper over said reinforcing element in a substantially
perpendicular orientation with the mould; and filling the
hopper with concrete such that the concrete flows through the
aperture to contact the concrete of the first portion.
Patent EP-1470144-A2 (EP)
Inventor: DAMHA MASAD J
IPC: A61P31/12
Filed: 2003-01-31
Abstract: The invention relates to oligonucleotides having alternating segments of sugar-modified nucleosides and 2′-deoxynucleosides, and uses thereof. The invention further related to oligonucleotides having alternating segments of sugar-modified nucleotides and 2′-deoxynucleotides, and uses thereof. Such uses include the preparation of antisense oligonucleotides and their use for the prevention or depletion of function of a target nucleic acid of interest, such as an RNA, in a system. Accordingly, and oligonucleotide of the invention is useful for therapeutic, analytical and diagnostic methods and uses, as well as component of compositions and commercial packages corresponding to such methods and uses.
Patent EP-1530637-A2 (EP)
Inventor: HARDING FIONA A
IPC: C12N9/54
Filed: 2003-02-26
Abstract: La présente invention concerne des méthodes d'identification d'épitopes des lymphocytes T dans les protéines de la subtilisine (Carlsberg). Elle concerne également la production de peptides modifiés qui, lorsqu'ils sont incorporés dans une protéine de la subtilisine (Carlsberg), produisent une réponse immunogène modifiée, de préférence une faible réponse immunogène chez l'homme. L'invention concerne en particulier des moyens, y compris des méthodes et des compositions, qui peuvent réduire de manière appropriée l'antigénicité de l'enzyme ALCALASE®.
Patent EP-1468061-A2 (EP)
Inventor: CRUIJSBERG EMIL EDUARD ANTONIU
IPC: C10G9/36
Filed: 2003-01-24
Abstract: A method for the preparation of lower olefins by steam cracking, wherein the feed containing heavy hydrocarbons obtained by Fischer-Tropsch synthesis is subjected to steam cracking in a naphtha designed steam cracking furnace for steam cracking the Fischer-Tropsch hydrocarbons into the lower olefins.
Patent EP-1470016-A2 (EP)
Title: Systeme ameliore de verrouillage de la position de parc du levier de la transmission automatique
Inventor: FLEMING WILLIAM R
IPC: F16H59/54
Filed: 2003-01-22
Abstract: L'invention porte sur un système amélioré de verrouillage de la position de PARC contrôlant les conditions dans lesquelles on dégage le levier (90) de la transmission automatique de la position de PARC. A cet effet un contrôleur (30) du système électronique et le contrôleur (16) de transmission sont raccordés à un bus commun (18) de données. Le système (10) électronique de commande du véhicule comprend le contrôleur (30) du système électronique (ESC) (30) dont il est le composant principal. L'ESC (30) gère, et communique avec, les différents contrôleurs spécialisés du véhicule (13) et exécute un programme de gestion des charges qui supervise la totalité des charges imposées au système électrique du véhicule (13) et au groupe propulseur par les différents accessoires de bord. Ces communications sont régies par un protocole usuel de communication, par exemple le SAE J1939, par l'intermédiaire du bus commun de données (18). L'ESC (30) est programmé pour assurer que le conducteur ne puisse pas dégager le levier de vitesse de la position de PARC sans avoir auparavant  appuyé sur la pédale du frein à pied, et il interdit ou permet les mouvements du levier de vitesse au moyen d'un système de verrouillage du levier actionné par un solénoïde.
Patent EP-1527324-A2 (EP)
Inventor: HINZ M
IPC: G01P3/487
Filed: 2003-06-19
Abstract: What is described is a magnetoresistive sensor for operation with a magnetized encoder, which is equipped with a zone with magnetic north and south poles arranged alternately along a direction of motion, comprising a Wheatstone bridge configuration with a first bridge arm between a first supply terminal and a first signal output terminal of the Wheatstone bridge configuration, a second bridge arm between the first supply terminal and a second signal output terminal of the Wheatstone bridge configuration, a third bridge arm between a second supply terminal and the first signal output terminal of the Wheatstone bridge configuration, and a fourth bridge arm between the second supply terminal and the second signal output terminal of the Wheatstone bridge configuration, wherein each of the bridge arms comprises an ohmic resistance element with a resistance-value dependence on the magnetic field strength of a magnetic field influencing the ohmic resistance element in accordance with a defined characteristic. For a further reduction in the spatial dimensions, the characteristics of the ohmic resistance elements in the first and fourth bridge arms are selected to be at least essentially matching with each other and significantly different from the characteristics, selected to be at least essentially matching with each other, of the ohmic resistance elements in the second and third bridge arms.
Patent EP-1505953-A2 (EP)
Inventor: STOLTZ CORINNE
IPC: A61P17/16
Filed: 2003-04-30
Abstract: La présente invention concerne de nouvelles compositions à usage topique à base de polyols-glycosides. Selon l'invention, ces compositions contiennent une quantité efficace d'un polyol-glycoside obtenu par acétalisation d'un polyol de Formule (I) dans laquelle n est un nombre entier égal à 2, 3 ou 4; ou de Formule (II) dans laquelle m est un nombre entier égal à 2 ou 3, avec un sucre réductueur.
Patent EP-1480702-A2 (EP)
Inventor: HICKLE RANDALL S
IPC: A61M16/01
Filed: 2003-02-25
Abstract: The invention provides a fail-safe module (FSM) integral with a sedation and analgesia system that meets the high-reliability needs of sedation and/or analgesia delivered by non-anesthetist practitioners. The FSM may operate in "real-time" in order to ensure optimal patient safety. The FSM may deactivate specific patient interfaces, user interfaces, and/or sedation and analgesia delivery in order to ensure patient safety and has redundant safety systems in order to provide the fail-safe module with an accurate assessment of controller functionality.
Patent EP-1495021-A2 (EP)
Inventor: LOHRAY BRAJ BHUSHAN
IPC: A61P31/00
Filed: 2003-03-26
Abstract: La présente invention concerne de nouveaux composés anti-infectieux, un processus de préparation de ces composés et des compositions pharmaceutiques les contenant.
Patent EP-1516088-A2 (EP)
Inventor: MILLER BALTHASAR
IPC: H01M8/10
Filed: 2003-06-06
Abstract: A fibrous, flat and ion-permeable material made of synthetic fibers, in particular of synthetically spun fibers such as acrylic fibers or aramid fibers, is processed into staple fibers of a specific length and then fibrillated. In a wet-laid inclined machine (paper machine), the fibrillated fibers are formed into a continuous web and then the web or portions of it are subjected to a temperature treatment to make the web electrically conducting by carbonizing/graphitizing the web through heating.