baber/WOPTO huggingface dataset:
Patent WO-2023211850-A1 (WO)
Title: Kcnt1 inhibitors comprising an isoxazole or oxadiazole core and methods of use
Inventor: GRIFFIN ANDREW MARK
IPC: A61K31/44
Filed: 2023-04-24
Abstract: Disclosed herein are compounds having an isoxazole core or an oxadiazole core or a pharmaceutically acceptable salt thereof and compositions useful for preventing and/or treating a neurological disorder, a disorder associated with excessive neuronal excitability, or disorder associated with a gain-of-function mutation in a gene (e.g., KCNT1). Methods of treating a neurological disorder, a disorder associated with excessive neuronal excitability, or disorder associated with a gain-of-function mutation in a gene, such as KCNT1, are also provided herein.
Patent WO-2023235088-A1 (WO)
Title: Dynamic audio optimization
Inventor: TINKLENBERG BETHANY
IPC: G06F3/16
Filed: 2023-05-02
Abstract: Systems and methods for dynamic audio optimization associated with digital content are provided. One or more audio profiles including one or more audio settings for one or more audio output devices available to a user may be stored in memory. An incoming audio stream associated with a current interactive session of the user and real-world audio within an identified real-world space where the user is located may be monitored. One or more audio deviations may be detected based on a comparison of the incoming audio stream and the real- world audio within the identified real-world space. An audio profile associated with the current interactive session may be automatically recalibrated to modify at least one of the audio settings. The audio output device may then process audio of the incoming audio stream in accordance with the at least one modified audio setting.
Patent WO-2024006027-A1 (WO)
Title: Synchronization of target wakeup times
Inventor: AJAMI ABDEL KARIM
IPC: H04W52/02
Filed: 2023-06-02
Abstract: Certain aspects of the present disclosure provide techniques for wireless communication at a station, generally including obtaining signaling indicating a resolution of a target wake time (TWT) field, determining a start time of a TWT service period (SP) based on the indicated resolution, and taking action based on the determined start time of the TWT SP.
Patent WO-2024006123-A1 (WO)
Title: Multiplexed volume hologram couplers for augmented reality waveguides
Inventor: RUSSO JUAN
IPC: G02B27/01
Filed: 2023-06-21
Abstract: Volume hologram couplers are multiplexed into a same volume to increase the field of view of components in a waveguide assembly such as an augmented reality (AR) waveguide assembly for use in electronic eyewear devices. The multiplexing can be done in any direction perpendicular to the optical axis. Multiplexing of the volume hologram couplers combines different functions of the waveguide assembly into one diffractive optical element (DOE) in the form of an input coupler or an output coupler. For example, each volume holographic grating of input couplers and output couplers has a different refraction angle, a different periodicity, or both relative to any other volume holographic grating in the same volume. The resulting DOEs reduce reinteraction losses, reduce thickness, reduce the amount of DOEs and the number of layers and airgaps, and increase robustness (volume versus surface relief that can scratch or break).
Patent WO-2023250074-A1 (WO)
Inventor: LUO SHUJUN
IPC: B65D51/28
Filed: 2023-06-22
Abstract: La présente invention concerne des dispositifs et des procédés de collecte d'un échantillon biologique. Le dispositif peut comprendre un capuchon, un contenant perçable comprenant un réactif pour traiter ou conserver un échantillon biologique, et un contenant qui comprend un dispositif de perçage. Lors de l'entrée en contact du capuchon avec une ouverture du contenant, le dispositif de perçage peut percer un contenant perçable, libérant ainsi le réactif du contenant perçable dans le contenant. Les procédés peuvent consister à utiliser le dispositif pour collecter un échantillon biologique. Les procédés peuvent consister à doser des analytes de l'échantillon biologique.
Patent WO-2024019898-A1 (WO)
Title: Apparatus and method for thermal foam detection
Inventor: SOCHA JEFFREY
IPC: C12M1/21
Filed: 2023-07-10
Abstract: A foam identification system including a thermal imaging camera and a controller connected to the thermal imaging camera. The thermal imaging camera images a surface of a liquid in a vessel that is exposed to a headspace of the vessel. The headspace being either warmer or cooler than the liquid. The camera and the controller detect a change in temperature of the exposed surface of the liquid to identify foam on the exposed surface of the liquid.
Patent WO-2023196877-A1 (WO)
Inventor: FARDIS MARIA
IPC: A61K35/17
Filed: 2023-04-05
Abstract: La présente invention concerne des procédés et des méthodes améliorés et/ou raccourcis pour préparer des TIL afin de préparer des populations thérapeutiques de TIL avec une efficacité thérapeutique accrue pour le traitement du cancer, y compris par exemple, le carcinome pulmonaire non à petites cellules (NSCLC), où le NSCLC est réfractaire au traitement avec un anticorps anti-PD-1 et/ou un anticorps anti-PD-Ll et/ou un inhibiteur du VEGF, et/ou où le cancer, y compris par exemple ou NSCLC, présente un score de proportion tumorale (TPS) prédéterminé, et y compris lorsque les TILs pour l'expansion sont obtenus avant que le patient ne reçoive un traitement anticancéreux.
Patent WO-2023205687-A1 (WO)
Title: Improved prime editing methods and compositions
Inventor: LIU DAVID
IPC: C12N15/10
Filed: 2023-04-19
Abstract: Disclosed herein are various improvements in prime editing (PE) relating to the optimization of various aspects and parameters of PE, including optimizing the conducting of PE and twin prime editing ("twinPE") experiments, as well as optimizing the design of pegRNAs and second-strand nicking guide RNAs.
Patent WO-2023212666-A1 (WO)
Title: Access policy token
Inventor: DYER ANTHONY
IPC: G06F21/33
Filed: 2023-04-27
Abstract: A method may include accessing a key from a secure storage. A payload may be encrypted using the key. A policy token may be generated. The policy token may include a publicly-readable header including a header identifier of the key and the payload encrypted using the key. The policy token may be sent. The policy token may be received. The publicly-readable header may be read. The key may be identified using the header identifier of the key from the publicly-readable header. The key may be accessed from the secure storage. The payload may be decrypted using the key.
Patent WO-2023220592-A1 (WO)
Inventor: GEBERTH JOHN
IPC: F02M61/12
Filed: 2023-05-09
Abstract: Le présent dispositif comprend une buse (100) d'un injecteur de combustible et un système de commande permettant de distribuer un combustible atomisé fin, lequel est mélangé uniformément à travers la charge d'air comprimé sur toute une large plage de positions d'étranglement. Le système comprend une tige d'aiguille (216) mobile de manière incrémentielle pour libérer un courant atomisé de combustible à haute pression à travers un ou plusieurs trous (50), afin de faire varier la taille de l'ouverture à travers laquelle le combustible est dirigé vers la charge d'air comprimé. Le combustible atomisé est distribué de manière à permettre aux particules fines de combustible d'être réparties uniformément à travers la charge d'air comprimé, afin d'obtenir une combustion plus complète et constante.
Patent WO-2023212752-A1 (WO)
Inventor: VERSFELD IAN
IPC: B63B34/67
Filed: 2023-04-26
Abstract: The invention provides a retainer (10) for retaining a ski rope (15). The retainer (10) includes an outboard engine cover attachment means (12) for attaching to a cover of an outboard engine (20) at one end and an elastic line attachment means (12) for attachment to an elastic line (14) at its other end, and an elastic line (14) attached to the attachment means. The ski rope retainer (10) further includes a means for attaching the free end of the elastic line (14) to or about the ski rope (15), in use.
Patent DK-201470744-A1 (DK)
Title: Magnetisk aktiverbart sikkerhedsafbryderarrangement
Inventor: HØJBJERRE MORTEN
IPC: H01H36/00
Filed: 2014-11-27
Abstract: The present invention relates to a magnetically activatable safety switch arrangement including an enclosure and an electric power safety switch ar- ranged inside the enclosure, wherein the electric power safety switch includes a switch housing with a set of contacts and an activation element, wherein the electric power safety switch is operable from a passive state to an activated state by displacing the activation element from a rest position to an activated position, wherein the activation element is biased towards its rest position, and wherein a first internal permanent magnet is arranged displaceably in the enclosure in order to displace the activation element of the electric power safety switch between its rest position and its activated position by interaction with an external magnet arranged outside the enclosure. A second internal permanent magnet is arranged inside the enclosure so that the switch housing of the electric power safety switch is arranged between the first internal permanent magnet and the second internal permanent magnet, in that the first and second internal permanent magnets are oriented so that they attract each other in order for the first internal permanent magnet to maintain the activation element of the electric power safety switch in its acti vated position as long as there is no interaction between the first internal permanent magnet and an external magnet, in that, in the passive state of the electric power safety switch, the set of contacts is in a closed state, and in that, in the activated state of the electric power safety switch, the set of contacts is in an open state.
Patent DK-201570348-A1 (DK)
Title: Anode clamp assembly and use of such assembly
Inventor: WIGANT LARS
IPC: E21B41/02
Filed: 2015-06-04
Abstract: An anode clamp assembly for attachment to a submerged structure is described. The anode is used for corrosion protection. The assembly comprises an elongate bar shaped or cylindrical anode arranged on a rod having rod ends extending from each end of the anode and clamps being attached to the rod ends. The assembly is easy to use and is suitable for being attached to a submerged structure by means of a Remote Operated Vehicle having a simple construction. Each clamp comprises two first legs having an intermediate bore arranged for rotation around a first rotation axis defined by the rod ends. Each of said first legs at a first end is provided with a griping jaw for attachment to a part connected to the structure and at a second end is hinged connected to a second leg via first hinges having a second rotation axis. The second legs are hinged to each other via a second hinge having a third rotation axis for forming an over-centre acting knee joint together with the two first legs. Said first rotation axis and said third rotation axis are arranged in a common plane being a symmetry plane for the clamp.
Patent DK-201700203-A1 (DK)
Title: Safety system for collaborative robot
Inventor: Mogens Rosenvang Rasmussen
IPC: B25J9/00
Filed: 2017-03-23
Abstract: The present invention relates to a safety system for a robot with one or more arms working to move loads from one position to another, in particular where the task is to stack layers of objects or goods on to pallets or vehicles, or to take objects (for example cans or boxes with different contents) from a multitude of positions to one packing position to provide the mix specified by a control program. In this situation it is convenient that persons can enter the working space to correct things or supply special goods in a safe way, which means the robot must be stopped while the persons are within the active range of the robot, but the robot can go on in its process after the persons have left the active range. According to the present invention, the safety of persons is provided by a scanner, which scans the active range of the robot below the load. In this way it is secured that persons cannot by mistake “hide” behind a load or a vehicle and go undetected into the robot’s work zone. In a particularly important case the robot is working from a gantry. The robot is mounted on a movable base plate connected to a rail track on the gantry. The gantry is placed on or above a floor with one or a multitude of conveyer bands or roller tracks situated alongside or perpendicular to the gantry on one or both sides of the gantry in such a way that it can move objects (for example cans or boxes) from one conveyer band to another, for example from a multitude of feeder conveyers with different types of objects to one (or more) collector conveyer(s) with mixed object content, for example on the opposite side of the gantry. The conveyer bands may transport boxes, pallets or similar collecting containers, and the robot may be used for stacking of such containers up to a certain height.
Patent DK-201970761-A1 (DK)
Title: Self-tailing winch
Inventor: ALBERT MAHONEY
IPC: B66D1/74
Filed: 2019-12-11
Abstract: Self-tailing winch with a release function, where said winch comprises: - a stator body adapted to be fastened on a surface; - a drum body arranged concentrically and rotatable around said stator body; - a self-tailing device arranged concentrically to said drum body, where said selftailing device comprises: - two self-tailing jaws defining an opening suitable to receive a rope, sheet or halyard; - a self-tailing cover which is rotatable relative to the drum body and the self-tailing jaws; - a releasable coupling arranged between the self-tailing cover and the self-tailing jaws, said coupling being able to couple the self-tailing jaws to the drum body and by manipulating the self-tailing cover releasing the self-tailing jaws from the drum body, allowing the self-tailing jaws to rotate relative to the drum.
Patent PH-12014500679-A1 (PH)
Title: Chimeric and humanized anti-cd44 antibodies that mediate cancer cell cytotoxicity
Inventor: YOUNG DAVID S F
IPC: G01N33/577
Filed: 2014-03-26
Abstract: CD44, a single chain hyaluronic acid (HA) binding glycoprotein, is expressed in a variety of normal tissues, all hematopoietic cells and several cancer tissues. A monoclonal antibody against CD44 from the hybridoma H460-16-2, deposited with the ATCC as PTA-4621, was previously shown to be a cancerous disease modifying antibody (CDMAB), preventing tumour growth and reducing tumour burden in cancer models including prostate and breast cancer by cytotoxicity. The variable regions of this monoclonal antibody were also isolated and sequenced to generate a chimeric antibody that had improved anti- cancer activity over the monoclonal antibody. Now, humanized antibodies are generated that have similar CD44 binding activity as the parent PTA-4621 monoclonal antibody. The monoclonal, chimeric and humanized antibodies can be conjugated to toxins, enzymes, radioactive compounds, cytokines, interferons, target or reporter moieties and hematogenous cells to treat cancer. These antibodies are also used in binding assays to determine CD44 expression on cells.
Patent PH-12015501392-A1 (PH)
Title: Pesticidal compositions and processes related thereto
Inventor: LO WILLIAM C
IPC: A01N37/46
Filed: 2015-06-17
Abstract: This document discloses molecules having the following formula ("Formula One"): and processes associated therewith.
Patent PH-12016000172-A1 (PH)
Title: A carton pallet board assembly
Inventor: CELSO E ABASTILLAS
IPC: E04C2/00
Filed: 2016-05-04
Abstract: A carton pallet board assembly comprised by plurality of webbed carton strips formed in polygon configurations with top and bottom web support strips, sides web support strips, and layers of flat carton board sheets where said plurality of webbed carton strips formed in polygon configurations are joined together by top, bottom, and sides web support strips which are then sandwiched and bonded between layers of flat carton board sheets to form the said carton pallet board assembly. Thus said webbed carton strips reinforces layers of flat carton board sheets that makes a rigid carton pallet board assembly to carry loads where primary material are from recycled carton boards other than woods, plastics, metals, and concrete, and where primary intended application is for carton pallets, walls, ceiling, flooring, table top and the likes. Also, said webbed carton strips can be formed with round or angled sides such as circle, spiral, S-shape, Z-shape, oblong, square, rectangular, triangular, and plurality of polygon sides.
Patent PH-12017050117-A1 (PH)
Title: A multi-grade separator and method of fabrication thereof
Inventor: NANTES RUBEN
IPC: B07B13/04
Filed: 2017-11-24
Abstract: Disclosed is a multi-grade separator for separating solid materials and method of fabrication thereof. Said separator comprises: a base frame with a plurality of under funnel partitioned downwardly beneath therein; a rotatable shaft having a screw leader blades mounted parallel to the base frame through a pair of pillow blocks; an intake funnel securely mounted on one end of the base frame being connected to the opposite side of the longitudinally oriented drum by a throat, characterized in that the longitudinally oriented drum comprises a plurality of chambers having a sieve of different size openings, wherein the first chamber is finest, second chamber is roughest than the first chamber, third chamber is roughest than the second chamber, fourth is roughest than third chamber, and fifth chamber is roughest than the fourth chamber.
Patent PH-12017500148-A1 (PH)
Title: Hair products containing branched amine functionalized silicone compounds
Inventor: LOPEZ BACA RAMON ARNOLDO
IPC: A61Q5/10
Filed: 2017-01-24
Abstract: The present disclosure pertains to compositions that include branched amine functionalized silicone compounds, methods involving the application of such compounds to hair, methods for making hair conditioners using such compounds, and uses of compositions containing such compounds for conditioning of hair for one or both of reducing tangling and increasing the ease of combing.
Patent PH-12017502111-A1 (PH)
Title: Three-dimensional striped structure
Inventor: TAKAOKA NOBUYUKI
IPC: B29C48/09
Filed: 2017-11-21
Abstract: Provided is a three-dimensional crosspiece structure in which a loop is formed by a continuous filament being partially welded in a random manner, which has a longitudinal direction that corresponds to the direction of extrusion and a transverse direction and a thickness direction that are perpendicular to the direction of extrusion, and which comprises a polyethylene-based thermoplastic resin, a polyester-based thermoplastic elastomer or a mixture of a polyethylene-based thermoplastic resin and a polyethylene-based thermoplastic elastomer, wherein the three-dimensional crosspiece structure has a rebound resilience of 13 cm or more, a hysteresis loss of not greater than 34 pcnt and not less than 13 pcnt , and a thermal elongation rate in the longitudinal direction of 0-8 pcnt before and after a hot air drying test. The three-dimensional crosspiece structure has a hysteresis loss and elasticity characteristics that are suitable for characteristics of the human body, and does not shrink when subjected to high temperature disinfection or the like.
Patent PH-12018000166-A1 (PH)
Title: Motor control apparatus
Inventor: IDE YUJI
IPC: H02P27/06
Filed: 2018-06-14
Abstract: A motor control apparatus is provided which does not shut down a system immediately even if current that is regenerated to a power supply exceeds a threshold during regeneration of power and, as a result, can operate a motor continuously even if imbalance occurs in a three-phase power supply. A motor control apparatus includes: a converter configured to convert three-phase AC power into direct current; an inverter connected to the converter and a motor, the inverter being configured to drive the motor; and a control circuit configured to control the converter, and the control circuit includes a maximum phase current value detection unit configured to detect a maximum value of a phase current, and a threshold comparison unit configured to compare the detected maximum value of the phase current with a threshold, and controls the converter in such a manner as to adjust a phase-to-phase voltage between two phases where current is flowing to zero upon the threshold comparison unit detecting that the maximum value of the phase current has reached a current limit threshold during regeneration of power.
Patent PH-12018501339-A1 (PH)
Title: Combination therapy
Inventor: GRIFFITH HUGH
IPC: A61P35/00
Filed: 2018-06-21
Abstract: This invention relates to a combination of gemcitabine-[phenyl-benzoxy-L-alaninyl)]- phosphate (chemical name: 2'-Deoxy-2',2'-difluoro-D-cytidine-5'-O-[phenyl (benzoxy- L- alaninyl)] phosphate) (NUC-1031) and a platinum-based anticancer agent selected from cisplatin, picoplatin, lipoplatin and triplatin. The combinations are useful in the treatment of cancer and particularly biliary tract and bladder cancer.
Patent PH-12018501572-A1 (PH)
Title: Positive-type photosensitive resin composition
Inventor: NAKAMURA TADAMITSU
IPC: G03F7/023
Filed: 2018-07-24
Abstract: A positive-type photosensitive resin composition comprising (a) a polybenzoxazole precursor, (b) a crosslinking agent, (c) a photosensitizing agent, and (d) a solvent, wherein the (a) component includes a structural unit represented by formula (1), and the (b) component is a compound represented by formula (2). In formula (1), U is a bivalent organic group, a single bond, -O-, or -SO2-, V is a group including an aliphatic structure, and the carbon number of the aliphatic structure is 1-30. In formula (2), R1 are each independently a hydrogen atom or a group represented by -CH2-O-R2. At least one of the plurality of R1 is a group represented by -CH2-O-R2. R2 are each independently a hydrogen atom or a C1-6 alkyl group.
Patent PH-12019500188-A1 (PH)
Title: Piperidine cxcr7 receptor modulators
Inventor: AISSAOUI HAMED
IPC: C07D413/14
Filed: 2019-01-25
Abstract: The present invention relates to piperidine derivatives of formula (I) wherein Ar1, Ar2, RAr1, R1, R2, and R3 are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as CXCR7 receptor modulators.
Patent PH-12020551044-A1 (PH)
Title: Steroids and antibody-conjugates thereof
Inventor: HAN AMY
IPC: C07J71/00
Filed: 2020-07-03
Abstract: Described herein protein steroid conjugates that are useful, for example, for the target-specific delivery of glucocorticoids (GCs) to cells.
Patent PH-12020551368-A1 (PH)
Title: Composition for enhancing cognitive function, composition for remedying anxiety symptoms, and composition for suppressing cerebral atrophy
Inventor: SATO HIDEAKI
IPC: A61P25/28
Filed: 2020-09-02
Abstract: The present invention provides a composition for enhancing cognitive function, a composition for remedying anxiety symptoms, and a composition for suppressing cerebral atrophy, which are highly safe and can be continuously ingested or administered. The compositions contain one or more selected from the group consisting of 25 mol pcnt to 45 mol pcnt of leucine and 20 mol pcnt to 40 mol pcnt of phenylalanine relative to the total content of leucine, lysine, valine, isoleucine, phenylalanine, histidine, and tryptophan.
Patent PH-12021550188-A1 (PH)
Title: Compositions comprising minerals, proteins and fatty acids for the treatment of mastitis
Inventor: SAMUEL TINU MARY
IPC: A61P43/00
Filed: 2021-01-21
Abstract: A mineral selected from the group consisting of iron, manganese and magnesium, or combination of two of more thereof; An n-3 fatty acid selected from the group consisting of docosahexaenoic acid (DHA) and 18:3 n-3 octadecatrienoic acid (alpha-linolenic acid); or a protein selected from the group consisting of alpha-lactalbumin, lactoferrin and albumin for use in treating or preventing mastitis in a subject.