baber/WOPTO huggingface dataset:
Patent EC-SP10010227-A (EC)
Title: Compuestos de 1,2,4,-triazin-3,5-diona adecuados para el tratamiento de trastornos que responden a la modulación del receptor de dopamina d3
Inventor: DRESCHER KARLA
IPC: A61K31/53
Filed: 2010-06-01
Abstract: Compuestos de la fórmula I:  en donde A es una cadena hidrocarbonada saturada o insaturada que tiene una longitud de cadena de 4 a 6 átomos de carbono, donde la cadena hidrocarbonada no está sustituida o está sustituida por 1, 2 ó 3 grupos metilo;R1 se selecciona del grupo formado por hidrógeno, C1-C3 alquilo y alquilo C1-C3 fluorado;R2 es hidrógeno, halógeno, ciano, C1-C3 alquilo, C1-C3 alcoxi, alquilo C1-C3 fluorado o alcoxi C1-C3 fluorado;R3 se selecciona del grupo formado por alquilo C4-C6 alquilo ramificado y cicloalquilo C3-C6, yR4  es alquilo C1-C6, cicloalquilo C3-C6, alquilo C1-C3 fluorado y cicloalquilo C3-C6 fluorado.y las sales tolerables para uso fisiológico de estos compuestos y sus N-óxidos.La invención también se relaciona con una composición farmacéutica que comprende al menos un compuesto de la fórmula I y/o al menos una sal de adición ácida tolerable para uso fisiológico del mismo, y además con un método para tratar trastornos que responden beneficiosamente a antagonistas del receptor de dopamina D3 o agonistas de dopamina D3, donde dicho método comprende administrar una cantidad eficaz de al menos un compuesto o una sal de adicíón ácida tolerable para uso fisiológico de la fórmula I a un sujeto que lo necesita.
Patent EC-SP11011470-A (EC)
Title: Nuevos derivados de pirimidina y sus usos en el tratamiento del cáncer y otras enfermedades
Inventor: THOM STEPHEN
IPC: A61K31/505
Filed: 2011-11-21
Abstract: La invención se refiere a compuestos de Fórmula (I); donde L1, R1, R2, R3, R4 y X son como se los define en la descripción. La presente invención también se refiere a procesos para la preparación de dichos compuestos, composiciones farmacéuticas que los contienen y su uso en el tratamiento de enfermedades, por ejemplo, cáncer.
Patent EC-SP12012051-A (EC)
Title: Líquidos nutricionales envasados asépticamente que comprenden beta-hidroxi-beta-metilbutirato (hmb)
Inventor: JOHNS PAUL W
IPC: A23L33/00
Filed: 2012-07-18
Abstract: Composiciones nutricionales que comprenden un envase aséptico tratado con peróxido y un líquido nutricional contenido en el mismo, en donde el líquido nutricional comprende beta-hidroxi-beta-metilbutirato (hmb) y al menos uno de grasas, hidratos de carbono, proteínas. El hmb provee un efecto amortiguador en el líquido nutricional para minimizar de este modo un desplazamiento ácido del ph que es prevalente en envases esterilizados asépticamente, y por lo tanto ayuda a mantener la estabilidad del producto en el tiempo.
Patent EC-SP13012468-A (EC)
Title: Absorbentes mejorados para eliminar el mercurio de las emisiones producidas durante la combustión de combustible
Inventor: NALEPA CHRISTOPHER J
IPC: C01B31/08
Filed: 2013-02-28
Abstract: El carbón activado se vuelve más estable térmicamente mediante la exposición a un aditivo no halogenado, y opcionalmente a un halógeno y/o compuesto que contiene halógeno. Tal carbón tratado es adecuado para su uso en la mitigación del contenido de sustancias tóxicas en los gases de escape, especialmente los gases de escape que tienen una temperatura dentro del rango de desde aproximadamente 100 ºC hasta aproximadamente 420 ºC.
Patent EC-SP14013221-A (EC)
Title: Fenil-3-aza-biciclo [3.1.0] hex-3-il-metanonas y su uso como medicamento.
Inventor: BERTANI BARBARA
IPC: C07D471/04
Filed: 2014-02-26
Abstract: Las presentes invenciones se refiere a fenil-3-aza-biciclo[3,1,0]hex-3-il-metanonas sustituidas de la fórmula general (I) (I)en dondeR1, R2, R3, R4, R5 y R6 son como se describen en la presente o sus sales, con preferencia, sus sales farmacéuticamente aceptables. La invención también se refiere a la preparación de dichos compuestos, composiciones farmacéuticas que comprenden un compuesto de acuerdo con la fórmula general (I) y el uso de dichos compuestos para el tratamiento de diversas condiciones tales como condiciones referidas a síntomas positivos y negativos de esquizofrenia, así como as alteraciones cognitivas asociadas con esquizofrenia, enfermedad de Alzheimer y otros trastornos neurológicos y psiquiátricos. Los compuestos de la invención muestran propiedades inhibidoras del transportador de glicina 1 (GlyT1).
Patent EE-200100041-A (EE)
Inventor: DARDER CARLOS PICORNELL
IPC: A61K47/38
Filed: 1999-07-20
Abstract: Pharmaceutical preparation comprising a compound having an antifungic activity as active principle, an inert core and a coat which includes said active principle, and is characterized in that said inert core has a particle size between 50 and 600  mu m, and is also characterized in that said coat has a unique layer which is produced by nebulization, on said inert core, of a solution which comprises a compound having an antifungic activity, a hydrophilic polymer and a non ionic surfactant. The method is carried out by means of a coating which comprises a unique layer of the inert cores having a size comprised between 50 and 600  mu m by nebulization of a solution comprised of the antifungic agent, the hydrophilic polymer and the non ionic surfactant at constant coating speed throughout the process; a single drying process of the coat is required with the same equipment.
Patent EG-25342-A (EG)
Title: Railway rail fastening clip.
Inventor: COX STEPHEN JOHN
IPC: E01B9/30
Filed: 2008-08-19
Granted: 2011-12-14
Abstract: A sealing plate for use with a rail clip anchoring device having a head and a stem which extends from the head into a concrete sleeper when the anchoring device is in use, is adapted for extending over the underside of the head when the stem of the device is being set in a concrete sleeper, thereby to prevent ingress of concrete into the head of the device, and for being retained on the surface of the sleeper thereafter. A major face of the plate, which is uppermost when the sleeper is in use, is provided with at least one clip seat portion for receiving part of a rail clip. In a method of manufacturing a concrete sleeper with at least one embedded rail clip anchoring device, the floor of a mold, from which the sleeper is to be formed, is provided with an aperture through which the head of an anchoring device is inserted and before concrete is introduced into the mold the aperture is sealed off around its edges and around the underside of the head of the anchoring device by placing a sealing plate over the aperture on the floor of the mold, the plate overlapping and sealing around the edges of the aperture other than where the anchoring device is located and having a mating interface with the anchoring device such that a seal is formed therewith.
Patent GB-189703571-A (GB)
Title: Improvements in the Construction of Fire-proof Buildings.
Inventor: VYGH ALBERT HENDRIK VAN DER
Filed: 1897-02-10
Granted: 1897-04-17
Abstract: 3571. V gh, A. H. van der, V gh, H. van der, and V gh, G. van der. Feb. 10. Building-blocks for walls &c. Blocks b, Fig. 5, made of the fireproof composition described in Specification No. 25,880, A.D. 1896, are superposed on each other with several laths c between and the spaces left filled in with cement. The blocks are locked together by short pins a, fitting into corresponding holes in the blocks, and may be further secured when necessary by metal clips or ties d. Slabs for ceilings are composed of the same ingredients as the wall blocks but in the proportions of coke dust 15 parts, lime 10 parts, tar 24 parts, plaster 28 parts, and water 23 parts.
Patent GB-189704091-A (GB)
Title: Improvements in or relating to Bricks or Blocks for Use in the Construction of Chimneys, Flues and other Shafts.
Inventor: BOULT ALFRED JULIUS
Filed: 1897-02-15
Granted: 1898-02-12
Abstract: 4091. Boult, A. J., [Granderath & Co., J. C.]. Feb. 15. Building-blocks for chimneys, flues, &c. The blocks are made with one, two, or more central apertures or flues z, z<1>, and of a depth equal to one, two, or more courses of ordinary brickwork. Side projections bond with the bricks of the wall, and the bedding surfaces are formed with interlocking ribs and recesses. Fig. 7 shows a form of block for inclined portions of the chimney. Holes may be made in the angles of the blocks to receive tie-rods, and metal strips e may be embedded in one side and grooves formed in the other side as seen in Fig. 8.
Patent GB-189708257-A (GB)
Title: Improvements in "Dobbies" employed in Looms for Weaving.
Inventor: HARLING RALPH
Filed: 1897-03-31
Granted: 1898-01-29
Abstract: 8257. Harling, R., and Harling, J., [trading as Harling & Todd]. March 31. Loom dobbies.-The joints between the baulk levers A and the jack levers B and catches C, D respectively are formed by studs E on the former fitting into holes in the latter, lateral motion being prevented by hooks F working in slots G. The feelers selected by the pegging-barrel are made alternately with straight and bent portions H<1>, I' for operating the upper and lower catches respectively. The Provisional Specification states also that the hook for operating the pegging-barrel is in two parts with a yielding connection, and that the pegging-barrel is prevented from moving more than the required distance by a lever with a projection to engage with notches in a wheel at the end of the shaft.
Patent GB-189709319-A (GB)
Title: Improvements in or relating to Machine-tools for Turning, Drilling, Boring, Milling, Planing, or Shaping Metals and other Materials.
Inventor: ROEDERER IGNATZ
Filed: 1897-04-12
Granted: 1898-04-02
Abstract: 9319. Roederer, I. April 12. Turning; boring and drilling; milling; planing and shaping; slotting.-The machine tool can be used for turning, boring, drilling, milling, slotdrilling, slotting, planing, or shaping metals or other materials. A main shaft d, driven by a speed cone f directly or through back gearing, operates through bevel gearing shafts l, l<1>, one of which rotates the spindle n, the other reciprocating a slide or ram i. Either shaft l, l<1> can be disconrected from its bevel-wheel so as to remain stationary. The frames o, o', p and r, r<1>, r<2> supporting the spindle n and slide i respectively can be clamped at an angle to the discs h, h<1> of the frame c supporting the driving-shaft d. The work may be clamped either on the disc v<1> or the slide v on the brackets v<2>, which can be raised and lowered on or turned round the pillar a. The disc v<1> may be secured on the spindle n and the work attached to it, the turning-tool being clamped in a standard R which can be fixed on the slide v. The slide i is provided with an additional tool-holder U' for shaping when the slide i is horizontal.
Patent GB-189713359-A (GB)
Title: A New or Improved Combination of Attachment Fastening and Collar Stud or Button for Scarfs, Bows, or the like purposes.
Inventor: MORTON THOMAS
Filed: 1897-05-31
Granted: 1898-03-26
Abstract: 13,359. Morton, T., and Taylor, G. May 31. Necktie fastenings and studs.-Studs for attaching neckties &c. in position are formed in either one or two parts, the latter preferably of the type described in Specification No. 12,113, A.D. 1895. The base of the stud is formed as a metal plate 9 to which a double pin 11 is hinged at one end. The other end of the plate is pierced and upset to form catches 13 for the pins. The pins may be bent at 14 to give a spring action.
Patent GB-189723508-A (GB)
Title: Improvements in and connected with Water Tight Doors for Ships.
Inventor: GOWDY WILLIAM HAMILTON
Filed: 1897-10-13
Granted: 1898-09-24
Abstract: 23,508. Gowdy, W. H. Oct. 13. Bulkhead doors.-Relates to an arrangement for automatically closing bulkhead doors, when water rises in the compartment. A casting d is attached to the framing of the door, and the two halves c of a divided nut are pivoted above the casting by links E, and below to a pin P working in a slot G. In the normal open position, a stop T on the pivoted lever l engages with a projection V on the casting d, but as soon as a float, which is connected to the lever by an arrangement of linkwork, is raised by the water in the compartment, the lever l is pulled over and the weight of the door pushes upon the halves of the divided nut and allows the door to fall. When the water has been pumped out of the compartment the nut falls into engagement with its screw, and the door can be raised by rotating the screw by means of a hand-wheel, a balance weight being provided to facilitate its rising.
Patent GB-189724673-A (GB)
Title: Improvements in Shower Baths.
Inventor: WEDLER AUGUST HEINRICH WILHELM
Filed: 1897-10-25
Granted: 1898-09-10
Abstract: 24,673. W e d- 1er, A. H. W. Oct. 25. Spray - producers for shower baths. The water from a pressure supply enters the chamber A by a tangential passage B. A nozzle C is screwed on to the lower end of the chamber A.
Patent GB-189728931-A (GB)
Title: Improvements in Devices for Disconnecting or Unyoking Horses from Vehicles.
Inventor: GREB-CLEEMANN JOHANN PETER
Filed: 1897-12-07
Granted: 1898-10-22
Abstract: 28,931. Greb-Cleemann, J. P. Dec. 7. Hooks.-Traces &c. F are connected to the vehicle &c. by a slipping-device which consists of a part A pivoted at D, and provided with an arm B for the trace &c. and an arm C for engagement with a spring bolt G, Fig. 2, or a projection G, Fig. 6, operated by or formed on a pivoted lever J. The lever J, Fig. 2, is concaved as shown, so that, by turning it, the bolt is withdrawn. The arm C, Fig. 2, may be dispensed with, and the bolt G made to engage a hook holding back a spring bolt in the arm B. A notched ring turning on the part E, Fig. 6, and engaging with the end M of the arm C, may be employed to prevent accidental disengagement
Patent GB-189810238-A (GB)
Title: Improvements in Apparatus for Automatically Regulating or Controlling the Working of Pumps.
Inventor: WETMORE EARL PORTER
Filed: 1898-05-04
Granted: 1898-06-18
Abstract: 10,238. Wetmore, E. P. May 4. Governing or con. trolling pumps foi steam generators, hydraulic accumulators, or other purposes. The valve b, controlling the supply of steam or other motive fluid to the pump, is connected with the piston d, the lower surface of which is exposed to the pressure of the steam and the upper to that of the delivery, so that when the latter becomes excessive the valve b closes. The piston-rod e<1> passes through the casing, so that the effective area of the upper side of the piston is less than that of the lower. A spring j may be provided for adjusting the pressure at which the valve closes. The valve may also be operated by hand.
Patent GB-189810283-A (GB)
Title: Improvements in and connected with Paint Kegs or Drums, Tins, and the like.
Inventor: DOWLING EDMUND
Filed: 1898-05-05
Granted: 1898-07-16
Abstract: 10,283. Dowling, E., Pinchin, E. S., Dowling, C. E., and Hill, A. C. May 5. Paint cans.-A paint keg or drum, tin, or the like is adapted to be used as a paint pot or, when empty, as a bucket. The lid c, which is secured by clips d or otherwise, is provided with handles m. A handle which is used when the vessel is employed as a paint pot, or as a bucket, is #-shaped, and is pivoted to studs l, over which, owing to the slits k, it can be slid when not in use. The handle is preferably lined underneath with wood.
Patent GB-189814292-A (GB)
Title: Improvements in Ball Cocks or Float Valves.
Inventor: LEONARD PETER
Filed: 1898-06-28
Granted: 1899-04-29
Abstract: 14,292. Leonard, P. June 28. Ball and float valves. -T h e valve B i s attached to a pivoted arm A having abutments E to engage projections e on the float lever F, a small motion of which suffices to fully open or close the valve. A shoulder L limits the motion of the lever. The supply pipe D, which may be provided with a protecting-nozzle G, may be screwed into a fitting H to facilitate its removal for re-facing. The Provisional Specification describes a modification, in which a plunger, working airtight in a cylinder, is connected to the rod of the main ball. This device acts as a cushion, and its cylinder has an air valve which is opened by an auxiliary ball when the water in the tank has risen nearly to its full height, and allows the main valve to close.
Patent GB-189824485-A (GB)
Title: An Improved Measuring and Controlling Cock.
Inventor: WIBERG GEORG
Filed: 1898-11-19
Granted: 1899-10-21
Abstract: 24,485. Wiberg, G. April 21, [date applied for under Sec. 103 of Patents &c. Act, A.D. 1883]. Measured quantities, delivering.- A measuring-vessel a is divided into two equal parts e, f by a partition d; the two parts are alternately filled and emptied by the cocks g, h, the plugs of which are actuated by the lever i and slotted lever l on moving the handle m to one side or the other. The upper cock k g works a counter. When the handle m is in an intermediate position no flow takes place, and, by moving it to the same side repeatedly, the contents of one part may be drawn off in small quantities. Float valves at n, n allow of air venting but prevent overflow of the liquid.
Patent GB-189826438-A (GB)
Title: Improvements in or relating to the Manufacture of Boots and Shoes.
Inventor: FAIRE GEORGE HENRY
Filed: 1898-12-14
Granted: 1899-10-14
Abstract: 26,438. Faire, G. H., and Faire, A. W., [trading as Smith, Faire, & Co.]. Dec. 14. Nailing.-Relates to devices to be applied to " Boston," " Barrett," and similar nailing- machines to enabie them to be used for tacking the upper to the sole of "Veldtshoen" goods. On the nozzle A of the machine is secured a tube B by means of a spring C. This tube is grooved to guide the edge of the sole, the walls of the groove holding the upper firmly against both sides of the sole. Machines used for this work alone have the nozzle A grooved as described with regard to the movable tube B.
Patent GB-189826543-A (GB)
Title: An Improved Smoke Consuming Apparatus for Steam Boiler Furnaces.
Inventor: GRANGER WILLIAM ARTHUR
Filed: 1898-12-15
Granted: 1899-04-22
Abstract: 26,543. Granger, W. A. Dec. 15. Smoke-consuming.- The furnace gases are passed below a mass of firebrick having passages through which heated air is discharged, or they may be passed between two such masses, or through a tube similarly constructed. Figs. 1 and 2 show one arrangement as fitted in the flue of a Lancashire boiler, Fig. 3 shows a modified arrangement, and Fig. 4 shows a method of applying the invention in the case of a water-tube boiler. As. shown in Figs. 1 and 2, an arch B, of firebrick, is located behind the bridge, and above it is an arched iron plate C. The arch B is supported on an air chamber F, on which also rests an inverted arch K. Air supplied to the chamber F by a steam jet or otherwise passes through the hollow supports to the space between the arch B and the plate C, whence it escapes through perforations in the arch B ; it also issues directly through perforations in the inverted arch K. In Fig. 3, the top arch is shown supported on one or more central hollow pillars D instead of the side supports M shown in Fig. 2. This arrangement is specially suitable for use in Galloway boilers. In Fig. 4, B and B<1> are two transverse firebrick structures with air passages and perforations, as shown in dotted lines.
Patent GB-189901077-A (GB)
Title: Improvements in Apparatus for use in Heating Railway Carriages.
Inventor: DRUMMOND DUGALD
Filed: 1899-01-17
Granted: 1899-12-02
Abstract: 1077. Drummond, D. Jan. 17. Heating.-The exhaust pipe B from the engine and the heating-pipe C to the carriages are connected by the apparatus shown, which contains a check valve A for the exhaust pipe, and a steam nozzle D from the locomotive boiler. By this arrangement the carriages are first heated by steam from the boiler, after which the heating is maintained by the exhaust steam.
Patent GB-189907759-A (GB)
Title: An Improved Process of Ornamenting or Decorating Polished Wood Surfaces.
Inventor: ASSINDER GEORGE FREDERICK
Filed: 1899-04-13
Granted: 1899-06-10
Abstract: 7759. A s s i n d e r , G. F., [Topp, W.]. April 13. Woodworlc, ornamental. - A French - polished wood surface is ornamented by removing parts of the polish to form a design, with a solvent such as amyl acetate mixed with fine slaked lime, applied with a brush or pen, or through a resist. This may be a coating of wax, gelatine, waterproofed paper, or the like, from which parts are removed ; after dissolving the varnish thus exposed, the resist is removed by heat or warm water. Or a thin metal or celluloid stencil plate may be used attached temporarily to the polished surface with mutton fat containing a little pitch.
Patent GB-189908740-A (GB)
Title: Improvements relating to Gas Cooking and other Stoves.
Inventor: WRIGHT JOHN WILLIAM BERNARD
Filed: 1899-04-26
Granted: 1900-03-03
Abstract: 8740. Wright, J. W. B., and Darwin, H. April 26. Gas burners, atmospheric.-In gas cooking and like stoves, the gas supply cocks or nozzles C are adjusted centrally with regard to the inlet ends of the injector tubes D, by being mounted upon a gas pipe A which is provided with stems A<1>, these stems being adjustably secured within sockets B<1> on the side plate B of the stove.
Patent GB-189910241-A (GB)
Title: Improvements in Electrical Incandescence Lamps with Osmium Filaments.
Inventor: IMRAY OLIVER
Filed: 1899-05-15
Granted: 1900-05-12
Abstract: 10,241. Imray, O., [Oesterreichische Gasgl³hlicht und Electricitõts-Gesellschaft]. May 15. Incandescent lamps. - Filaments are made of osmium, or osmium with a small proportion of carbon or a hydrocarbon, or with a small or large amount of a metal such as zirconium, thorium, niobium, or tantalum, or silicon. An osmium filament may be made as described in Specification No. 1535, A.D. 1893, and heated in a hydrocarbon gas at low pressure, to introduce a small proportion of carbon, or coated with a paste of zirconia or other oxide and carbon, sugar, or other carbonaceous material, and heated to incandescence in a vacuum or reducing-gas, to reduce or partially reduce the oxide. The reduction may also be effected by gas previously occluded in the osmium filament. Or the mixed materials may be formed into a filament and heated similarly ; other platinum metals may be included in them. The filaments may be subsequently coated with refractory oxides. The filaments are mounted in clean bulbs of glass containing no easily-reducible oxides, preferably an infusible potash-soda glass. The bulb is filled with dry hydrogen or illuminating- gas, and exhausted at a high temperature, rinsing out several times with dry gas. The filament is heated to intense whiteness until it ceases to give off gas, during exhaustion, and the bulb is sealed after admitting a very small quantity of hydrogen or illuminating-gas. The filament is afterwards improved by moderate incandescence for a long time.
Patent GB-190005124-A (GB)
Title: Improvements in and relating to Axle Boxes and Plummer Blocks, and in the Journals of Axles and Shafts therefor.
Inventor: KATONA ANDREAS
Filed: 1900-03-17
Granted: 1900-06-16
Abstract: 5124. Katona, A., Varga, P., and Krompecher, J. March 17. Axles; axle-boxes, lubricating.-The axle a has shrunk on to it a hard steel or brass sleeve b with bevelled sides, and the brass c is kept from shifting by the stud z. The oil in the bearing is kept at a constant level by the bird-fountain lubricator f carried by a stirrup g detachably secured to the axle-box.
Patent GB-190005865-A (GB)
Title: Improvements in or connected with Biscuit and similar Canisters or Boxes.
Inventor: CRAWFORD ARCHIBALD INGLIS
Filed: 1900-03-29
Granted: 1900-05-05
Abstract: 5865. Crawford, A. I. March 29. Cans, opening.-The paper fastening or covering of tin canisters or boxes for biscuits &c. is cut by a string d placed immediately below the flange of the lid, one end of the string being secured at d<2> to the canister, and the free end having a tab d' to be laid hold of.