baber/WOPTO huggingface dataset:
Patent AU-2020351825-A1 (AU)
Title: Method and system for performing non-invasive genetic testing using an artificial intelligence (AI) model
Inventor: HALL JONATHAN MICHAEL MACGILLIVRAY
IPC: G16B50/00
Filed: 2020-09-25
Abstract: An Artificial Intelligence (AI) based computational system is used to non-invasively estimate the presence of a range of aneuploidies and mosaicism in an image of embryo prior to implantation. Aneuploidies and mosaicism with similar risks of adverse outcomes are grouped and training images are labelled with their group. Separate AI models are trained for each group using the same training dataset and the separate models are then combined, such as by using an Ensemble or Distillation approach to develop a model that can identify a wide range of aneuploidy and mosaicism risks. The AI model for a group is generated by training multiple models including binary models, hierarchical layered models and a multi-class model. In particular the hierarchical layered models are generated by assigning quality labels to images. At each layer the training set is partitioned in the best quality images and other images. The model at that layer is trained on the best quality images, and the other images are passed down to the next layer and the process repeated (so the remaining images are separated into next best quality images and other images). The final model can then be used to non-invasively identify aneuploidy and mosaicism and associated risk of adverse outcomes from an image of an embryo prior to implantation.
Patent AU-2020355394-A1 (AU)
Title: Process for preparing (R)-4-aminoindane and corresponding amides
Inventor: ZANARDI GIAMPAOLO
IPC: C07C211/45
Filed: 2020-09-23
Abstract: The present invention relates to a process for preparing 1,1,3 -trimethylindan-4-amine of formula (I), or a salt thereof, enriched in one of its two enantiomers, in particular the enantiomer (R), (I) which comprises the chiral separation of an optionally substituted 2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline of formula (III). The present invention also relates to a process for preparing optically active amides of formula (II), (II) starting from said compounds of formula (I).
Patent AU-2020358815-A1 (AU)
Title: Frequency-shift determination
Inventor: BOOIJ WILFRED EDWIN
IPC: G01S5/18
Filed: 2020-10-02
Abstract: A receiving apparatus (7) that can estimate a motion-induced frequency shift in a received signal comprises a processing system (205) and a receiver (204) configured to receive a signal comprising one or more instances of a transmitted signal. The processing system (205) is configured to generate data representative of a plurality of impulse response functions by deconvolving the received signal with each of a plurality of templates representative of the transmitted signal shifted in frequency by a different respective frequency shift. The processing system (205) is further configured to evaluate a signal-to-noise measure for each of the plurality of impulse response functions, and to identify an impulse response function of the plurality of impulse response functions for which the signal-to-noise measure satisfies a peak criterion.
Patent AU-2020364930-A1 (AU)
Title: A mesenchymal stem cell storing or transport formulation and methods of making and using the same
Inventor: PHAN TOAN THANG
IPC: A01N1/02
Filed: 2020-10-08
Abstract: The disclosure relates to a mesenchymal stem cell storing or transport formulation, a method of preparing and using said formulation. It also includes a method of treating a subject having a disease such as a wound by topically administering mesenchymal stem cells that have been stored or transported in the storing or transport formulation. Also concerned is a unit dosage of the mesenchymal stem cells. In the preferred embodiment, the formulation comprises HypoThermosol®, human serum albumin and Plasmalyte.
Patent AU-2020369219-A1 (AU)
Title: A topical antibiotic containing pharmaceutical composition for bacterial infections and wound healing
Inventor: SULUR VISHAGAN VANANGAMUDI
IPC: A61K9/00
Filed: 2020-10-19
Abstract: A Pharmaceutical composition for treating bacterial skin infections, burns and wounds is disclosed. It comprises an active ingredient, preferably Mupirocin, a biopolymer, preferably Chitosan, with molecular weight ranging from 250,000 Da to 600, 000 Da, and a degree of deacetylation of not less than 80%, hydrolyzed Collagen, preferably of type I, with molecular weight ranging from 3 kDa to 6 kDa, and an ointment base comprising emulsifying agents, glycols and solubilizers. The invention has improved stability than the existing ointments, it heals skin and re-epithelializes faster than existing treatments thereby reducing hospitalisation period.
Patent AU-2020370165-A1 (AU)
Title: Compositions comprising superfine compounds and production thereof
Inventor: JACKSON H MATTHEW
IPC: A61K47/40
Filed: 2020-10-21
Abstract: The present invention provides stable, non-degradable edible, inhalable, soluble and drinkable compositions comprising highly bioavailable pharmaceutical grade ultrafine active pharmaceutical ingredients having 99% purity and 200% increased bioavailability, and methods for their production.
Patent AU-2020372904-A1 (AU)
Title: Anaerobic blood storage and pathogen inactivation method
Inventor: SUTTON JEFFREY
IPC: A01N1/02
Filed: 2020-10-28
Abstract: Relates to a method for pathogen reduction of a blood product comprising: i) removing oxygen from a blood product; ii) reducing blood pathogens from said blood product t: adding amustaline (S-303) to a final concentration of 0.2 millimolar (mM); and glutathione (GSH) to a concentration of 20 mM; iii) reducing S-303 to a concentration of less than 1 nmol/L comprising incubating said oxygen reduced blood product under oxygen reduced conditions for up to 6 hours; and further relates to a pathogen reduced, oxygen reduced blood product having an oxygen saturation (sO
Patent AU-2020376003-A1 (AU)
Title: Bearing assembly
Inventor: MAAS JR KARL
IPC: F16L27/08
Filed: 2020-10-28
Abstract: A rotational coupling including a bearing assembly including a first race rotatably coupled to a second race, wherein the first race is configured to receive a plurality of first fasteners to couple the first race and the bearing assembly to a fluid supply. The rotational coupling also including a connection flange coupled to the second race and configured to receive a plurality of second fasteners to couple the connection flange to the second race. The second race includes a first side facing the connection flange and a second side opposite the first side and facing the first race, wherein the second race includes at least one access aperture configured to enable access to the plurality of first fasteners from the first side to removably couple the bearing assembly to the fluid supply.
Patent AU-2020385370-A1 (AU)
Title: Shareable and nested transactions on hash chains
Inventor: SCOTT GLENN CARTER
IPC: H04L9/00
Filed: 2020-05-14
Abstract: DOCKET NO.: 37202/808WO1; 1811466WO 
ABSTRACT 
A method for using shareable and nested transaction on hash chains includes 
storing transaction data of a transaction of a hash chain. A lock block is appended to the 
hash chain. Appending the lock block includes setting a tail block identifier of the hash 
chain from a preceding tail block of a preceding transaction to the lock block. A data 
block is appended to the hash chain. Appending the data block includes setting the tail 
block identifier of the hash chain to the data block. The method further includes 
removing the transaction data from the transaction without invalidating the hash chain.  
The method further includes appending an updated data block to the hash chain to 
update the transaction with updated transaction data.  
34
Patent AU-2020421792-A1 (AU)
Title: Sealing bag with reminding function
Inventor: LIU FENGLING
IPC: B65D33/16
Filed: 2020-04-02
Abstract: Disclosed is a sealing bag with a reminding function, the sealing bag comprising a bag body (1) and at least one set of first sealing rib strips (3), wherein each set of first sealing rib strips (3) comprise a first convex rib strip (31) and a first concave rib strip (32), the first convex rib strip (31) and the first concave rib strip (32) are respectively arranged on two sides of an opening of the bag body (1), the inner side of the first convex rib strip (31) forms alternating concave portions (312) in the lengthwise direction of the first convex rib strip, convex portions (311) are formed on the outer sides of the concave portions (312), the first concave rib strip (32) comprises dumbbell-shaped grooves (321) that are arranged at intervals, and the first convex rib strip (31) and the first concave rib strip (32) make a sound in the process of the first convex rib strip (31) being embedded into or separated from the dumbbell-shaped grooves (321) of the first concave rib strip (32). The sealing bag has a good sealing effect, and when the opening is sealed and opened, the first convex rib strip (31) and the first concave rib strip (32) make a sound so as to achieve the function of giving an alert.
Patent AU-2020430412-A1 (AU)
Title: Connection device for door and window frames
Inventor: LIN RUIFENG
IPC: E06B3/964
Filed: 2020-02-18
Abstract: A connection device for door and window frames comprises a main body (1) and two bases (2). The two bases (2) are respectively disposed on two opposite side surfaces of the main body (1) so as to attach to frames (9) adjacent to the two opposite side surfaces of the main body (1). The connection device for door and window frames can optimize the installation efficiency and appearance of doors and windows, folding window screens, or retractable window screens.
Patent AU-2020481686-A1 (AU)
Title: Wellbore packer with expandable metal elements
Inventor: PELTO CHRISTOPHER MICHAEL
IPC: E21B34/10
Filed: 2020-12-18
Abstract: A wellbore packer system includes a mandrel positionable within a wellbore. The system further includes a wellbore packer positionable around the mandrel. The wellbore packer includes an expandable metal sealing element positionable around a first portion of the mandrel to form a long-term seal within the wellbore in response to exposure of the expandable metal sealing element to wellbore fluid. Additionally, the wellbore packer includes an elastomeric sealing element positionable around a second portion of the mandrel to form a short-term seal in response to receiving a seal-setting force. Moreover, the wellbore packer includes a setting piston positionable to apply the seal-setting force on the elastomeric sealing element.
Patent WO-2021212167-A1 (WO)
Title: Échangeur de chaleur à poudre/gaz et applications correspondantes
Inventor: SCEATS MARK GEOFFREY
IPC: F28C3/12
Filed: 2021-04-01
Abstract: L'invention concerne un échangeur de chaleur à poudre/gaz pour échanger de la chaleur entre un courant de poudre et un courant de gaz dans un écoulement à contre-courant comprenant un débit massique de courant de poudre sensiblement égal à un débit massique de courant de gaz dans un échangeur de chaleur à arbre vertical. Un courant de gaz chaud peut être conçu pour être utilisé pour chauffer un courant de matières solides froides, ou un courant de gaz froid peut être conçu pour être utilisé pour refroidir un courant de matières solides chaudes.
Patent WO-2022120407-A1 (WO)
Title: Ensemble connecteur pour meubles
Inventor: ASQUITH WARREN
IPC: F16B5/06
Filed: 2021-08-24
Abstract: La présente invention concerne un ensemble connecteur (8) destiné à être utilisé dans des meubles pour maintenir un premier panneau (6) adjacent à un second panneau (7). L'ensemble connecteur (8) comprend un corps (9) destiné à être fixé au premier panneau (6), une base (10) destinée à être fixée au second panneau (7), un actionneur (11) comprenant une surface d'entraînement (35) qui coopère avec une surface de contact (36) sur l'un quelconque des éléments parmi la base (10) ou le corps (9) de sorte que la rotation de l'actionneur (11) autour d'un axe d'actionneur vers une position sécurisée amène la surface d'entraînement (35) à coulisser sur la surface de contact (36) produisant une action de came pour tirer la base (10) et le corps (9) ensemble.
Patent AU-2021200569-A1 (AU)
Title: Noninvasive diagnosis of fetal aneuploidy by sequencing
Inventor: FAN HEI-MUN CHRISTINA
IPC: G01N33/48
Filed: 2021-01-29
Abstract: NONINVASIVE DIAGNOSIS OF FETAL ANEUPLOIDY BY SEQUENCING 
ABSTRACT 
Disclosed is a method to achieve digital quantification of DNA (i.e., counting differences 
between identical sequences) using direct shotgun sequencing followed by mapping to the 
chromosome of origin and enumeration of fragments per chromosome. The preferred method 
uses massively parallel sequencing, which can produce tens of millions of short sequence tags in 
a single run and enabling a sampling that can be statistically evaluated. By counting the number 
of sequence tags mapped to a predefined window in each chromosome, the over- or under
representation of any chromosome in maternal plasma DNA contributed by an aneuploid fetus 
can be detected. This method does not require the differentiation of fetal versus maternal DNA.  
The median count of autosomal values is used as a normalization constant to account for 
differences in total number of sequence tags is used for comparison between samples and 
between chromosomes.
Patent AU-2021200926-A1 (AU)
Title: Device and method for producing spacers with a variable head
Inventor: VOGT SEBASTIAN
IPC: B29C39/24
Filed: 2021-02-12
Abstract: DEVICE AND METHOD FOR PRODUCING SPACERS WITH A 
VARIABLE HEAD 
Abstract 
The invention relates to a device for producing a spacer having a casting mold (1), wherein the 
casting mold (1) has a stem mold (34) and a mold cavity (32) with a spherical surface-shaped 
inner surface, wherein the stem mold (34) and the mold cavity (32) delimit a common interior, at 
least one filling opening (2) and at least one vent element (15), wherein the stem mold (34) is 
dimensionally stable on injection of bone cement paste into the casting mold (1), while, on 
injection of bone cement paste into the casting mold (1), the mold cavity (32) is expandable at 
least in the region of the spherical surface-shaped inner surface by pressure imparted by the 
injected bone cement paste.  
The invention also relates to a method for producing spacers using such a device.  
(Figure 1)
1/28 
22 24 26 12 9 16 18 14 34 1 
21 42 5 
18 23 5 
16 
32 
19 
33 
30 
52 28 
48 
15 
17 
20 
e13 9 8 
32 10 
25 27 35 39 29 
Figure 1
Patent AU-2021201187-A1 (AU)
Title: 2-(het)aryl-substituted condensed heterocyclic derivatives as pest control agents
Inventor: Fischer Rüdiger
IPC: A01N43/653
Filed: 2021-02-24
Abstract: HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS 
PESTCONTROLAGENTS 
Abstract 
The invention relates to novel compounds of formula (I), wherein RR2, R3, A', X and n are 
defined as cited in the description, to the use thereof as acaricides and/or insecticides for 
controlling animal pests, and to methods and intermediate products for the production of said 
compounds.
Patent AU-2021204689-A1 (AU)
Title: Methods for treating lithium-containing materials
Inventor: MAGNAN JEAN-FRANCOIS
IPC: C22B3/04
Filed: 2021-07-05
Abstract: : The present disclosure relates to a method for extracting lithium from a lithium
containing material. For example, the method can comprise leaching a roasted lithium
containing material under conditions suitable to obtain an aqueous composition comprising a 
lithium compound such as lithium sulfate and/or lithium bisulfate. The aqueous composition 
comprising lithium sulfate and/or lithium bisulfate can optionally be used, for example, in a 
method for preparing lithium hydroxide comprising an electromembrane process. The 
roasted lithium-containing material can be prepared, for example by a method which uses an 
aqueous composition comprising optionally lithium sulfate and/or lithium bisulfate which can 
be obtained from a method for preparing lithium hydroxide comprising an electromembrane 
process such as a two-compartment monopolar or bipolar electrolysis process.
Patent AU-2021204757-A1 (AU)
Title: Skeletal animation in embodied agents
Inventor: HUTTON JO
IPC: G06N20/00
Filed: 2021-07-07
Abstract: The claimed invention provides system and method to improve Skeletal Animation. The claimed invention is 
related to an Actuation System, a Combiner, a Mapper, an Animation Mixer and a Motion Interpolator and 
Predictor. It aims to automate the changing of captured motion data defining the skeleton parameters in a 
realistic manner without human intervention. The claimed invention can be applied to all geometry controls 
that are based on manipulating with character skeleton parameters. It can also be used for controlling 
poses of non-human characters and creatures. Each component of the system can be used by itself or in 
combination with other algorithms.
8/9 
Motion Interpolation Training Data 
Set of Poses 
Target Point Locations 11 
p1(x,y,z) Skeletal Posei 
p2(X,y,Z) Skeletal Pose 2 
Actuation Unit Descriptor 
Target Point Locations 3 
p1(x,y,z) Actuation Unit Descriptorl 
p2(X,y,Z) Actuation Unit Descriptor2 
Motion 
Interpolator and Combiner 
F Intrpolating 
11 
17 
Wi, W2,-...I 
Skeletal Ps 
Desired Point 7 
Location 
p(x,y,z) 
FIGURE 11
Patent AU-2021208027-A1 (AU)
Title: Substituted triazinones as thyroid hormone receptor agonists
Inventor: ZHOU JINGYE
IPC: A61P35/00
Filed: 2021-01-13
Abstract: The application relates to a compound of Formula (I') or (I), or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of thyroid hormone receptors, a pharmaceutical composition comprising a compound of Formula (I') or (I), and a method of treating or preventing a disease or disorder regulated by thyroid hormone.
Patent AU-2021216566-A1 (AU)
Title: Implant for fusing at least two bone components and method of fusing bone components using the implant
Inventor: MEDOFF ROBERT
IPC: A61F2/30
Filed: 2021-02-05
Abstract: An implant for fusing at least two bone components and method of using the implant. The implant has a body with first and second anchoring portions. The first anchoring portion has a stem configured to be directed to within a first bone component and is further configured to cooperate with at least a first fastener usable to fix the stem in an operative position relative to the first bone component. The second anchoring portion is configured to overlie at least a second bone component at a placement location at which bone has been strategically removed and is further configured to cooperate with at least a second fastener usable to fix a part of the second anchoring portion to the second bone component with the second anchoring portion in an operative position.
Patent AU-2021218675-A1 (AU)
Title: Anti-ACVR1 antibodies and uses thereof
Inventor: IDONE VINCENT J
IPC: A61P19/08
Filed: 2021-02-10
Abstract: The present invention provides monoclonal antibodies that bind to the Activin A type I receptor (ACVR1) protein, and methods of use thereof. In various embodiments of the invention, the antibodies are fully human antibodies that bind to ACVR1. In some embodiments, the antibodies of the invention are useful for inhibiting ACVR1-mediated bone morphogenetic protein (BMP) signal transduction, thus providing a means of treating or preventing a disease, disorder or condition associated with ACVR1.
Patent AU-2021223138-A1 (AU)
Title: Methods and compositions for modulating arginine levels in immune cells
Inventor: CHEUNG KWOK MING
IPC: A61K35/17
Filed: 2021-02-20
Abstract: Provided are genetically modified T-cells and CAR-T cells that have an increased ability to process the essential amino acid arginine, for example, by overexpressing amino acid transporters, particularly arginine transporters. The genetically modified T-cells and CAR-T cells can survive the often hostile tumor microenvironment better because of their increased ability to process arginine. Also provided are the methods and compositions used to augment the amount of arginine available to a T-cell, thus providing a CAR-T cell that can be effective in the treatment of solid tumors by surviving the tumor microenvironment.
Patent AU-2021225838-A1 (AU)
Title: Methods for treating endometriosis
Inventor: SAFE STEPHEN
IPC: A01N43/42
Filed: 2021-02-24
Abstract: Methods of treating endometriosis through modulation of Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) activity including administration of an NR4A1 ligand to an individual in need thereof are described. In an embodiment, the compounds include methylene substituted diindolylmethanes.
Patent AU-2021230666-A1 (AU)
Title: Air-conditioning apparatus
Inventor: WATANABE KAZUKI
IPC: F24F110/10
Filed: 2021-02-10
Abstract: This air conditioner comprises a refrigerant circuit in which a compressor, an outdoor heat exchanger, a throttle device, and an indoor heat exchanger are connected by a pipe through which a refrigerant is circulated. The air conditioner further comprises an indoor blower for supplying indoor air to the indoor heat exchanger, and a control device for controlling the compressor and the indoor blower. When a cooling operation is started, the control device causes the compressor to operate. When a first set time has elapsed since the operation of the compressor started, the control device causes the indoor blower to operate at a wind speed less than a set minimum wind speed. When a second set time has elapsed since the operation of the indoor blower at the wind speed less than the set minimum wind speed started, the control device causes the indoor blower to operate at the set minimum wind speed. When a third set time has further elapsed since the operation of the indoor blower at the set minimum wind speed started, the control device causes the indoor blower to operate at a set wind speed.
Patent AU-2021233788-A1 (AU)
Title: Skimming devices and related methods
Inventor: VAN DER MEIJDEN HENDRIKUS JOHANNES
IPC: E04H4/12
Filed: 2021-03-02
Abstract: Skimming device (10) which has a floatable head (14) and with adjustable means for adjusting the head position to the waterline.
Patent AU-2021267900-A1 (AU)
Title: Uterine-derived regenerative cell compositions and uses thereof
Inventor: BLACK LINDA
IPC: A61K35/36
Filed: 2021-05-06
Abstract: The present disclosure relates to heterogeneous cell compositions derived from canine or feline uterine tissue and methods of producing and use thereof. In some aspects, the heterogeneous cell compositions comprise a mixture of mesenchymal progenitor cells and epithelial progenitor cells. In some aspects, the heterogeneous cell compositions are used as an autologous or allogeneic treatment for the treatment of diseases such as chronic kidney disease, atopic dermatitis, immune mediated arthritis, hepatitis, liver disease, inflammatory bowel disease, osteoarthritis, intravertebral disc disease, keratoconjunctivitis sicca (dry eye), pancreatitis, fibrosis, sclerosis, amyloidosis, immune mediated polyarthritis or wounds in canines and felines.
Patent AU-2021276930-A1 (AU)
Title: Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha
Inventor: GERMINARO MATTHEW
IPC: A61K45/00
Filed: 2021-05-20
Abstract: A method of treating inflammatory bowel disorders, such as ulcerative colitis, comprises administering an IL-23 inhibitor, such as an anti-IL-23p19 antibody (e.g., guselkumab) and a TNF-α inhibitor, such as an anti-TNF-α antibody (e.g., golimumab).
Patent AU-2021281566-A1 (AU)
Title: Multi-cavity customizable dosage forms
Inventor: HOWARD MATTHEW A
IPC: A61K31/192
Filed: 2021-05-21
Abstract: An improved customizable dosage form comprising a substrate, such as a tablet core, that has two or more distinct, discrete cavities on opposing sides of its exterior surface; and/or two or more distinct, discrete cavities on a first side of its exterior surface and an identification feature on a second opposing side of its exterior surface. A process for making such a customizable dosage form wherein one or more active ingredients and inactive ingredients such as colors, flavors and/or sensates are deposited into at least one of the cavities.