baber/WOPTO huggingface dataset:
Patent IL-140287-A0 (IL)
Title: Methods for rapidly identifying small organic ligands
IPC: G01N33/50
Filed: 1999-06-25
Abstract: The present invention is directed to novel methods for rapidly and unambiguously identifying small organic molecule ligands for binding to biological target molecules. Small organic molecule ligands identified according to the methods of the present invention may find use, for example, as novel therapeutic drug lead compounds, enzyme inhibitors, labeling compounds, diagnostic reagents, affinity reagents for protein purification, and the like. Also presented are novel methods for identifying high affinity binding ligands for a biological target molecule of interest, wherein those methods comprise linking two or more small organic molecule ligands previously identified as being capable of binding to the biological target molecule of interest. Biological target molecules include, for example, polypeptides, nucleic acids, carbohydrates, nucleoproteins, glycoproteins, glycolipids and lipoproteins.
Patent IL-144978-A0 (IL)
Title: A decontamination composition containing chloroisocyanuric acid, methods for the preparation thereof and kits containing the same
IPC: A62D3/36
Filed: 2000-02-15
Abstract: A decontamination formulation is provided which is effective against a broad spectrum of chemical and biological warfare agents and radioactive dusts, comprising an active decontamination agent, a co-solvent, a buffer system to optimize the initial reaction pH above 8.5 and more preferably in the range of 10 to 11 for favoring oxidation of VX and HD and hydrolysis of G agents, and a surfactant similar to fire-fighting foaming agent. Formulations comprise, in water by weight, 1% to 15% of a hydrated chloroisocyanuric acid salt, 1% to 10% of a polypropylene glycol co-solvent, 1% to 15% surfactant and a buffer system to initially maintain said formulation at a pH from about 11 to about 8.5 for sufficient duration to effect decontamination. The formulation can be provided in kit form or concentrate form, be prepared, in part, in advance or on site, and be dispensed in foam form which aids in coating and adhering of the decontamination formulation to contaminated surfaces. All ingredients can be pumped through a foam nozzle or water, co-solvent and surfactant can be pumped to the nozzle with solutions of buffer and of active ingredient being introduced at the nozzle for minimizing pump exposure.
Patent IL-148017-A0 (IL)
Title: Magnetised transducer element for torque or force sensor
IPC: G01D5/12
Filed: 2000-08-14
Abstract: A magnetic torque transducer for a structure such as a disc through which torque is transmitted between a central shaft to which the disc is mounted and an outer periphery such as a gear wheel. The intervening region through which torque is transmitted is magnetized to provide a transducer element having two magnetized, annular regions which cooperate to emanate a magnetic field that is torque-dependent. The two magnetized regions may be longitudinally-magnetized through the disc or circumferentially magnetized with opposite polarities. A sensor assembly of non-contacting sensors is used to detect the emanated field and connected in circuitry to provide a torque-dependent signal. In an alternative a single magnetized annular region is employed. The annular region or regions need not be a complete annulus. The same disc-like structure can also be used as force sensor for measuring bending moments or other forces which result in stress occurring in the disc.
Patent IL-148170-A0 (IL)
Title: Amino acid derivatives which influence the activity of dipeptidyl peptidase iv and pharmaceutical compositions containing the same
IPC: C07K5/037
Filed: 2000-08-20
Abstract: Amino acid cyclic amide derivatives (I) are new. Amino acid cyclic amide derivatives of formula (I) are new. B-A-C (I) A : an alpha -amino acid with a side-chain functional group; B : a molecule covalently bonded to the side-chain functional group of A, selected from oligopeptides with a chain length of up to 20 amino acids, polyethylene glycol (PEG) with a molecular weight of up to 20,000, optionally substituted organic amines, amides, alcohols, acids or aromatics with 8-50 C atoms; C : a thiazolidine (Thia), pyrrolidine, hydroxyproline, dehydroproline or piperidine group forming an amide bond with A. ACTIVITY : Antiinflammatory; antiallergic; dermatological; antiarthritic; antipsoriatic; immunomodulator; cytostatic. MECHANISM OF ACTION : Dipeptidyl peptidase IV (DP IV) modulator. The serum DP IV activity of rats after oral administration of 5 mu M Glu(PEG)-Thia was increased by almost 10% after 20 minutes and then decreased to 90% of the initial level over the next 100 minutes.
Patent IL-151794-A0 (IL)
Title: Polishing agent and method for producing planar layers
IPC: H01L21/304
Filed: 2001-03-19
Abstract: There is provided a process for polishing monocrystalline semiconductor materials of silicon and germanium to a high degree of surface perfection comprising polishing the material with a modified colloidal silica sol having a pH between about 11 to 12.5 and composed of colloidal silica particles which are coated with chemically combined atoms of aluminum to give a surface coverage of about 1 to about 50 aluminum atoms on the surface per 100 silicon atoms on the surface of uncoated particles. The particles of the modified silica sol used in the process of the invention have a specific surface area of about 25 to about 600 square meters per gram with the silica concentration of the sol ranging from about 2 to about 50% by weight.
Patent IL-151981-A0 (IL)
Title: Method of treating hepatitis delta viral infection
IPC: A61P43/00
Filed: 2001-03-29
Abstract: A method for the treatment for hepatitis delta infection in a host, that includes administering an effective amount of a nucleoside or a nucleoside analog that suppresses the expression of the hepatitis B surface or preS1 antigen in the host 100-fold or more relative to pretreatment values in vivo; or to not more than 1 microgram per milliliter in vivo. In a preferred embodiment, the nucleoside is L-FMAU, or a pharmaceutically acceptable salt or prodrug thereof.
Patent IL-151984-A0 (IL)
Title: Sub-calibre projectile and method of making such a projectile
IPC: F42B14/06
Filed: 2001-03-30
Abstract: The present invention relates to a composed projectile for subcalibre projectile comprising a sabot, a projectile and a driving speculum, whereby said composed projectile comprises a projectile made of a metal material, preferably having a high density, and that the length of the composed projectile is not substantially longer than the projectile, as well as a cartridge comprising such a composed projectile.
Patent IL-154087-A0 (IL)
Title: Novel use of a peptide class of compound for treating non neuropathic inflammatory pain
IPC: A61K38/00
Filed: 2002-03-19
Abstract: The present invention concerns the use of compounds of the Formula (I): <CHEM> for treating different types and symptoms of acute and chronic pain, especially non neuropathic inflammatory pain in mammals. The pain to be treated may be e.g. chronic inflammatory pain, rheumatoid arthritis pain and/or secondary inflammatory osteoarthritic pain. The compounds show an antinociceptive profile and differ from classical analgesics like opioids and non-steroidal anti-inflammatory drugs (NSAIDS) and are useful as specific analgesics.
Patent IL-158491-A0 (IL)
Title: 2-iminopyrrolidine derivatives
IPC: C07D405/06
Filed: 2002-04-19
Abstract: The present invention relates to a 2-iminopyrrolidine derivative selected from the group consisting of 1-(3-tert-butyl-4-methoxy-5-morpholino-phenyl)-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-ethanone; 1-{3-tert-butyl-5-[4-(2-hydroxy-acetyl)piperazin-1-yl]-4-methoxyphenyl}-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-diyhdro-isoindol-2-yl)-ethanone; ethyl (4-{3-tert-butyl-5-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-acetyl]-2-methoxy-phenyl}piperazin-1-yl)-acetate; 1-(3-tert-butyl-4-methoxy-5-piperazin-1-yl-phenyl)-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-ethanone, and (4-{3-tert-butyl-5-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-acetyl]-2-methoxy-phenyl}-piperazin-1-yl)-acetic acid; and salts thereof.
Patent IL-160300-A0 (IL)
Title: Method for the continuous laying of a rail on a rigid track, in addition to an alignment device and a rigid track
IPC: E01B21/00
Filed: 2003-07-06
Abstract: The invention relates to a method for the continuous laying of a rail (4,4') on a rigid track, in particular consisting of precast concrete components (1). According to said method, the rail (4,4') is positioned in a channel (3,3') of the rigid track and is fixed by said channel (3,3') being filled. The inventive method is characterised in that chamber filler blocks (30) are located at the sides of the rail (4,4') and the gap (32) between the chamber filler blocks (30) and the sides (34) of the channel is filled with a grouting mortar.
Patent IL-176834-A0 (IL)
Title: Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis
IPC: A01N43/40
Filed: 2006-07-13
Abstract: A composition comprising at least a pyridylethylbenzamide derivative of general formula (I) (a) and a compound capable of inhibiting the ergosterol biosynthesis (b) in a (a) / (b) weight ratio of from 0.01 to 20. <??>A composition further comprising an additional fungicidal compound. <??>A method for preventively or curatively combating the phytopathogenic fungi of crops by using this composition.
Patent IL-177072-A0 (IL)
Title: Esters of hyaluronic acid and rhein, processes for the preparation thereof and pharmaceutical compositions containing the same
IPC: C08B37/08
Filed: 2006-07-25
Abstract: The present invention relates to esters of hyaluronic acid with rhein, more particularly to a compound based on hyaluronic acid, wherein alcohol groups of hyaluronic acid are esterified with rhein, to a process for preparing said ester and to a pharmaceutical composition comprising said ester.
Patent RO-126220-A0 (RO)
Title: Process and installation for exploiting depleted gas fields with high water content
Inventor: NIŢĂ PETRE
IPC: E21B43/12
Filed: 2011-02-02
Abstract: The invention relates to a process and an installation for exploiting a gas field with relatively high water content. According to the invention, the process consists in separating water from gas at the level of a carrier bed and depositing the same in a bag located thereunder, the gas flowing to the surface through an annular space between a production column and an extraction tubing, the water in the bag being then either injected into a lower receiving bed or extracted to the surface by a submersible pump, the said water injection being made either by means of a surface compressed gas column, or by means of a pump with one or two pistons, another pump being used in case water is extracted to the surface.
Patent RO-126471-A0 (RO)
Title: Mechanical curing press
Inventor: POLLNER COSMINA ANDREEA
IPC: B29D30/08
Filed: 2011-03-31
Abstract: The invention relates to a simple, robust, reliable mechanical curing press with large size platens meant to cure members of different sizes and configurations. According to the invention, the press comprises two driving systems () which operate alternatively and discontinuously and drive two identical or different shafts (), as the case may be, into translation motion, accompanied or not by a rotation motion, the main driving system () acting simultaneously and synchronously on two gears consisting of a worm () and a worm gear (), as the case may be, and the secondary driving system () acting simultaneously and synchronously on two other identical gears consisting of a worm () and a worm gear (), one or more force detecting elements () or one or more force detecting systems () being capable to measure with sufficient accuracy three force values, all adjustable and pre-adjusted, one minimal, one maximal, and one intermediary, preferably the average one.
Patent RO-131332-A0 (RO)
Title: Process for preserving saccharose in sugar beet
Inventor: DE LANGE PAUL
IPC: C13B10/00
Filed: 2016-04-18
Abstract: The invention relates to a process for preserving saccharose in sugar beet. The process, as claimed by the invention, consists in treating the ground sugar beet roots by microwave heating for 30...480 s, at a power of 700 W, a frequency of 915 MHz, while maintaining the temperature of the ground sugar beet mass at a temperature of at least 70°C, for at least 10 s, after which some preservation additives of ethanol type are added, the resulting mixture being subjected to extraction of sugars.
Patent RO-131780-A0 (RO)
Title: Method and device for hybrid speed-position control with applications in intelligent control platforms
Inventor: VLADAREANU LUIGE
IPC: G05D13/00
Filed: 2016-11-14
Abstract: The invention relates to a method and a device for the hybrid control of speed and position with applications in intelligent platforms for real-time control of robots and mechatronic systems. According to the invention, the method consists in that, for the hybrid speed-position control of the motion trajectory in a tridimensional space, generated by a final effector of a robot or mechatronic system, actuated on m freedom degrees by a number of m actuators of high mechanical hysteresis, intermediate incremental position references are generated by serial approximation sequences associated to the control of the moving speed of the actuator, with generation of incremental speed references for the respective serial approximation sequences, according to a certain algorithm, so that the motion of the final effector actuated by the actuator or by the m actuators on the freedom degrees of the robot or mechatronic system, takes place only on the direction of the actuator, while eliminating the movement oscillations on the trajectory of the final effector. The device, as claimed by the invention comprises: a number of i intelligent control interfaces receiving signals from some inertial, force and visual sensors (S, S, S) mounted on a robot or mechatronic system, and signals concerning the current position (P) and current speed (V) of the robot or mechatronic system, a decision module (MD), a control module and a generator module (MG) which generates position and speed references, a data bus module (MDT) and a communication module (MC), as well as a position controller, a speed controller, a control module for the joints space, a module for conversion of digital signals into analogue signals and a number of m servo motors for the m freedom degrees of the robot or mechatronic system, and the controlled robot or mechatronic system.
Patent AP-2000001775-A0 (AP)
Title: Method for controlling machine piston movement, implementing device and balancing off said device.
Inventor: NEGRE GUY
IPC: F02B75/32
Filed: 2000-03-24
Abstract: The invention concerns a method for controlling a machine piston movement for carrying out operations such as gas transfer in engines with independent combustion chamber or such as ignition and combustion in standard engines, at a constant volume by stopping the piston and maintaining it in its upper dead centre position for a time interval. The invention also concerns an implementing device wherein the piston (1)is controlled by a pressure lever (3, 4)which itself controlled by a crankshaft (9)and a connecting rod (7)
Patent MC-2142-A1 (MC)
Inventor: HUDSON ALAN THOMAS
IPC: C07C50/32
Filed: 1989-10-26
Abstract: The present invention relates to the use of 2-[4-(4-chlorophenyl) cyclohexyl]-3-hydroxy-1,4-naphthoquinone or a physiologically acceptable salt or other physiologically functional derivative thereof for the manufacture of a medicament for the treatment and/or prophylaxis of toxoplasmosis in animals, to pharmaceutical compositions for the treatment and/or prophylaxis of toxoplasmosis, comprising said compound as active ingredient and to a method of treating or preventing toxoplasmosis in an animal which comprises administering to said animal an effective amount of said compound.
Patent ZW-4888-A1 (ZW)
Title: Novel anilide herbicides
Inventor: DAVID MUNRO
IPC: C07C233/56
Filed: 1988-04-29
Abstract: A novel herbicide of formula I <CHEM> wherein R1 represents a halogen atom or an alkyl, haloalkoxy, haloalkyl or alkoxycarbonyl group;      R2 represents a hydrogen or halogen atom; each of R3 to R6 independently represents a hydrogen or halogen atom or a cyano, alkyl, haloalkyl, alkoxy or haloalkoxy group; R7 represents a hydrogen or halogen atom, or an alkyl, haloalkoxy, haloalkyl or alkoxycarbonyl group; and A represents a nitrogen atom or a -CH- group, together with its formulation and use as a herbicide, and its preparation.
Patent IE-910292-A1 (IE)
Title: A process for preparing a medical pack
Inventor: O'GRADY THOMAS
IPC: A61B19/08
Filed: 1991-01-29
Abstract: This invention relates to a process for preparing a medical pack which includes a number of surgical linens for surgical operations and procedures. The process comprises of sorting through soiled surgical linens to remove foreign objects, separating the linens into different categories, laundering each category separately, inspecting the linens and rejecting any which are inadequately cleaned or have defects, folding of the linen in a manner which will not break the sterile barrier, and assembling a pack containing said linens for the aforesaid surgical operations and procedures. The inspection of the laundered linens preferably includes the step of back lighting each to detect defects. The process of sterilisation is preferably carried out by a steam and vacuum drying process, which includes a 'telltale' tape to indicate when sterilisation has occurred.
Patent LU-83240-A1 (LU)
Inventor: HATFIELD R
IPC: B29C65/18
Filed: 1981-03-19
Abstract: A heat sealing machine for producing a drum of spirally wound layers of thermoplastic polymeric sheet material heat sealed together having a rotatable horizontal shaft for receiving thermoplastic polymeric sheet material spirally wound thereon by rotation of the shaft; a heater adapted to be positioned between and adjoining a first polymeric sheet layer being spirally wound on the shaft and a prior layer wound on the shaft; and a support, for the heater, displaceable with respect to the shaft axis so that the heater can remain radially adjacent a drum surface on which another spiral layer is to be heat sealingly attached. A portion of the heater can be readily formable into cylindrical shell segments of varying radii when positioned between the two polymeric sheet layers.
Patent MA-20625-A1 (MA)
IPC: B02C17/04
Filed: 1986-02-07
Abstract: PCT No. PCT/BE86/00003 Sec. 371 Date Oct. 6, 1986 Sec. 102(e) Date Oct. 6, 1986 PCT Filed Jan. 27, 1986 PCT Pub. No. WO86/04526 PCT Pub. Date Aug. 14, 1986.A device which regulates the retention time of material ground in a grinding mill is disclosed. The device comprises a cylindrical casing, a wall in the casing having a plurality of apertures therethrough, a reservoir chamber defined between the wall and a side of the casing, lifting structure in the reservoir chamber, and a reservoir scoop spaced from the casing and extending into the resevoir chamber. The discharge scoop comprises a hollow longitudinal member including a first opening on its upper surface and a second opening on its lower surface, with the openings being spaced longitudinally from each other.
Patent MA-21943-A1 (MA)
Inventor: C L BRANCHE
IPC: C07D501/20
Filed: 1990-09-03
Abstract: 7 beta -[2-(aminothiazolyl and thiadiazolyl)-2-oxyiminoacetamido]cephalosporin derivatives having a 3-[N-(optionally substituted) aminopyridiniumthiomethyl] substituent have antibacterial activity and are of use in antibacterial therapy. Processes for the preparation of such cephalosporins plus intermediates for use in the preparation thereof, including N-(optionally substituted)amino-thiopyridones, are also described.
Patent MA-26920-A1 (MA)
Inventor: CARPINO PHILIP ALBERT
IPC: C07D471/04
Filed: 2002-12-24
Abstract: A compound of the formula  wherein R3, R4, R6, R7, X4, Q and HET are as defined above, useful for the treatment or prevention of disorders, diseases or conditions responsive to the activation of melanocortin receptor.
Patent MA-27217-A1 (MA)
Title: Dispositif de connexion pour l'extremite d'un cable de commande
Inventor: ANGELO TANCREDI
IPC: F16C1/12
Filed: 2004-06-30
Abstract: Perfectionnements de mécanismes de chasse de réservoirs WC Les perfectionnements sont axés sur une nouvelle disposition et l'assemblement de divers éléments de flottation avec des moyens de retenue du trop-plein (20) pour un maintien en position stable, que ce soit pendant une vidange partielle et/ou pendant une vidange totale. L'invention est aussi axée sur la structure particulière de la cloche base (1) qui est montée sur la pipe de sortie d'eau de la citerne. Il est important de souligner que les nouveaux éléments de flottation sont facilement adaptables à divers mécanismes de chasse de réservoirs. D'autres perfectionnements ont trait à un tuyau désaxé (24) solidarisé à un pont support et à la structure d'une pièce particulière associée au dispositif de vidange, ce tuyau servant en même temps aussi de guide du trop-plein (20) par son rebord supérieur.
Patent MA-20150037-A1 (MA)
Title: طريقة لمعالجة مياه الصرف الصحي عن طريق الطين وبصفة خاصة للتخلص من المواد العضوية عن طريق التجلط
Inventor: ASSOBHEI OMAR
IPC: C02F3/10
Filed: 2013-07-01
Abstract: ويتعلق هذا الاختراع بإمكانية استخدام الطين الطبيعي (البيرلايت) لإحداث التجلط لمياه الصرف الصحي المنزلي. تم تقييم القدرة على التجلط من خلال القضاء على الطلب الكيميائي على الأكسجين (coض) ومادة التعليق (mىص). وقد درس تأثير التجلط و درجة الحموضة على فاعلية عملية التجلط، وكذلك تم دراسة الشروط الأفضل إزالة coض و mىص . في حالة مياه الصرف الصحي المنزلي، فإن الجرعة المثلى من البيرلايت (25 ملج / لتر) يعطي كفاءة إزالة 66.77٪ من درجة حموضة مياه الصرف الصحي المعالجة. في مقابل، جرعة من كبريتات الألومنيوم تبلغ 100 ملج / 1 و جرعة من الجير تبلغ 200 ملجم / لتر ، تتم إزالة نسبة من coض لتصل فقط إلى 52.57٪ و 49.15٪ على التوالي. الجرعة المثلى للمادة التي تسبب التجلط أقل من جرعة كبريتات الألومنيوم والجير المستخدمة. وقد تم فحص تأثير درجة الحموضة على تجلط الدم في الجرعة المثالية من 25 ملج/ 1 من البيرلايت.
Patent MA-38567-A1 (MA)
Title: Variantes de pertuzumab et leur évaluation
Inventor: GENNARO LYNN A
IPC: G01N33/53
Filed: 2014-04-15
Abstract: La présente invention concerne des variantes de pertuzumab. Elle concerne notamment : une variante à cystéines non appariées comprenant des cystéines cys23/cys88 non appariées dans l'un ou les deux domaines légers variables du pertuzumab, une variante afucosylée du pertuzumab, une espèce à poids moléculaire faible (lmws) du pertuzumab, et une espèce à poids moléculaire élevé (hmws) du pertuzumab. L'invention concerne également les variantes isolées, des compositions, des compositions pharmaceutiques et des articles fabriqués comprenant les variantes, ainsi que des procédés de préparation et de caractérisation des variantes et leurs compositions.
Patent MA-43503-A1 (MA)
Title: Arn viral simple brin isole (ssrna) derive du genome du virus de la peste equine (ahsv) pour la vaccination d'animaux contre le ahsv
Inventor: ROY POLLY
IPC: C12N15/46
Filed: 2017-04-10
Abstract: La présente invention concerne un arnsb isolé du virus de la peste du cheval (ahsv) comprenant une pluralité de mutations ; une cellule complémentaire pour la réplication d'une souche virale vaccinale à partir dudit arnsb ; une souche virale vaccinale dérivée dudit arnsb ; l'utilisation de ladite souche virale vaccinale et/ou de l'arnsb isolé dans la vaccination d'un animal contre une infection par ahsv ; un procédé de vaccination comprenant celui-ci ; et une composition pharmaceutique comprenant ladite souche virale vaccinale et/ou ledit arnsb isolé.