baber/WOPTO huggingface dataset:
Patent MX-2021004251-A (MX)
Title: Compound derived from n-hydroxyphenyl-2-propyl-pentanamide (ho-aavpa) and its use for the treatment of breast cancer.
Inventor: ROSALES HERNÁNDEZ Martha Cecilia
IPC: A61P35/00
Filed: 2021-04-13
Abstract: The present invention relates to the 2,5-HO-AAVPA molecule as a structural analog of HO-AAVPA, designed by structural fragments of drugs involved in the epigenetic control of cancer. Said compound is a product of HO-AAVPA metabolism in preclinical assays, presenting a higher probability of anticancer activity and an accessible and efficient synthesis route for 2,5-HO-AAVPA. In vitro assays of the antiproliferative effect on MDA-MB-231 and MCF7 breast cancer cells showed a better action of 2,5-HO-AAVPA (24.6 ÁM and 69.8 ÁM, respectively) than HO-AAVPA, as well as minimal toxicity in non-cancer cells (NIH-3T3). Also, molecular recognition, determined by studies in silicon, of 2,5-HO-AAVPA by the enzymes HDAC1 and HDAC8 is thermodynamically favored assuming an inhibitory mechanism of the catalytic activity. Said results position 2,5-HO-AAVPA as a potential drug for breast cancer treatment in future clinical trials.
Patent MX-2021005313-A (MX)
Title: Mini-nucleosome core proteins and use in nucleic acid delivery.
Inventor: KOIRALA ADARSHA
IPC: C12N15/62
Filed: 2019-11-06
Abstract: The present disclosure provides compositions and methods relating to mini-nucleosome core proteins and/or delivery of nucleic acids. In particular, the present disclosure includes, among other things, non-viral proteinaceous vehicles for delivery of nucleic acids. In various embodiments, non-viral proteinaceous vehicles provided herein include (a) a nucleic acid binding domain; (b) a targeting domain; and, optionally, (c) a nucleic acid release domain, stability domain, and/or an oligomerization domain, and/or a linker domain.
Patent MX-2021006459-A (MX)
Title: Flow passage resistive body and heat exchanger.
Inventor: ODA TAKUO
IPC: F15D1/02
Filed: 2019-12-02
Abstract: In the present invention: a plurality of resistance impartment parts (34A-34E) are arranged adjacent to each other; and a first contraction flow part, which constitutes resistance impartment parts on one side among the resistance impartment parts (34A-34E) adjacent to each other, communicates with an increased diameter part constituting resistance impartment parts on the other side; and the first contraction flow parts (32AH-32DH) constituting the resistance impartment parts (34A-34E) adjacent to each other are arranged at different positions in the direction in which an outer frame member (31) extends.
Patent MX-2021008321-A (MX)
Title: Pharmaceutical compositions comprising (s)-4-(4-(4-(((2-(2,6-diox opiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and methods of using the same.
Inventor: AGRAWAL ANJALI
IPC: A61K47/26
Filed: 2020-01-08
Abstract: Provided herein are pharmaceutical compositions (e.g., oral dosage formulations) comprising (S)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-l-oxoisoindolin-4- yl)oxy)methyl)benzyl)piperazin-l-yl)-3-fluorobenzonitrile, or an enantiomer, mixture of enantiomers, tautomer, isotopolog, or pharmaceutically acceptable salt thereof, and a carrier or diluent. Also provided herein are methods of preparing and methods of using the pharmaceutical compositions.
Patent MX-2021009011-A (MX)
Title: Encoding and storage node repairing method for minimum storage regenerating codes for distributed storage systems.
Inventor: YANOVSKY DAVID
IPC: G06F16/182
Filed: 2020-01-29
Abstract: The present disclosure is based on erasure coding, information dispersal, secret sharing and ramp schemes to assure reliability and security. More precisely, the present disclosure combines ramp threshold secret sharing and systematic erasure coding.
Patent MX-2021009463-A (MX)
Title: Steel sheet.
Inventor: MURAKAMI TOSHIO
IPC: C22C38/58
Filed: 2020-02-12
Abstract: The present invention provides a steel sheet containing prescribed amounts of prescribed elements, the balance being iron and unavoidable impurities, and the steel sheet being such that: the total area ratio of bainite, bainitic ferrite, martensite, residual austenite, and a martensite/austenite mixed structure is 95-100% inclusive; the total area ratio of ferrite and pearlite is less than 5%; the area ratio of the martensite/austenite mixed structure is 5-30% inclusive; the average length of a cut piece of the martensite/austenite mixed structure is 0.32 µm or less; and the proportion of the area of a region in which cementite is not present among ferrite, bainitic ferrite, and martensite relative to the total area of the ferrite, the bainitic ferrite, and the martensite is 3.0-5.0% inclusive.
Patent MX-2021015010-A (MX)
Title: Fire protection system for sloped combustible concealed spaces having hips.
Inventor: MEYER STEPHEN J
IPC: A62C35/68
Filed: 2020-06-04
Abstract: A fire protection system is provided for a space having a roof including a pitched portion and at least one end portion having a hip, sloping downward from an apex substantially coinciding with an end of the pitched portion toward an cave and extending outward toward the ends of the sides of the pitched portion. The hip may have a lower hip, including jack trusses, and an upper hip, including stepdown trusses. Within the upper hip, at least two rows of sprinklers may be placed, with a first row of sprinklers located substantially at the apex. The maximum allowable spacing between sprinklers in a direction perpendicular to the slope of the hip may be greater than a maximum allowable spacing between rows of sprinklers, i.e., in a direction parallel to the slope of the hip.
Patent MX-2022001879-A (MX)
Title: Methods of genomic evaluation in livestock.
Inventor: KENDALL DAVID
IPC: C12Q1/68
Filed: 2017-04-12
Abstract: The invention encompasses methods for increasing genetic progress in livestock, and for genetic dissemination, including the use of amniocentesis to obtain fetal amniocytes for use in genomic evaluation and cloning.
Patent MX-2022003381-A (MX)
Title: Mining equipment inspection system, mining equipment inspection method, and mining equipment inspection device.
Inventor: FURTENBACH LARS
IPC: G06T7/00
Filed: 2020-06-30
Abstract: Disclosed is a computer-implemented point-cloud data acquisitioning method for acquiring point-cloud data of the inside of a mining equipment, the method comprising: acquiring from a sensor, a first dataset and a second dataset, wherein each dataset comprises datapoints at coordinates; extracting features from the first and second dataset; aligning the first and second dataset using the extracted features; combining the aligned first and second dataset into a point-cloud data; estimating a geometry of the mining equipment based on the point-cloud data; and identifying by use of the point-cloud data a region of the estimated geometry indicating insufficient data.
Patent MX-2022006325-A (MX)
Title: Metal surface-treating agent, and metal material with coating film and method for manufacturing same.
Inventor: IKO TOMOHIRO
IPC: C23C26/00
Filed: 2020-11-11
Abstract: The present invention addresses the problem of providing: a metal surface-treating agent which can form a coating film having excellent corrosion resistance and hydrophilicity in or on a surface of a metal material; a method for manufacturing a metal material with a coating film; and a metal material with a coating film, which is manufactured by the manufacturing method. A chemical substance comprising a water-soluble or water-dispersible resin (A) and a compound (B) having a nitrile group and an amino group in specified amounts can form a coating film having excellent corrosion resistance and hydrophilicity in or on a surface of a metal material, and therefore can solve the problem.
Patent MX-2022006421-A (MX)
Title: Devices and methods for assessing vascular access.
Inventor: MAJERUS STEVEN
IPC: A61B7/04
Filed: 2020-11-25
Abstract: An apparatus can be used for detecting acoustic signals of a vascular system. The apparatus can comprise at least one acoustic sensor. Each acoustic sensor can comprise a structure defining a hole therethrough. A piezoelectric layer can define a first side and an opposing second side. The piezoelectric layer can extend across the hole of the structure. A first electrode can be disposed on the first side of the piezoelectric layer. A second electrode can be disposed on the second side of the piezoelectric layer. A polymer engagement layer can be positioned against the first side of the piezoelectric layer and can be disposed at least partially within the hole of the structure.
Patent MX-2022007390-A (MX)
Title: Breath gas analysis.
Inventor: DRLIK MARK SASHA
IPC: A61B5/087
Filed: 2020-12-16
Abstract: Systems and methods have been developed for implementation of a breath testing system for convenient sampling of intestinal gases exhaled from a patient's breath. This may include a system with a manifold that includes thermal regulation components, for instance thermistors and resistive heating elements, which maintain the temperature of the gases above the body temperature of the patient. In some examples, the system will determine an indication of whether a patient has SIBO by adjusting a change in exhaled hydrogen concentration by a methane level exhaled by a patient.
Patent MX-2022007540-A (MX)
Title: An absorbent hygienic article for absorbing body fluids.
Inventor: FINGAL LARS
IPC: A61F13/15
Filed: 2019-12-20
Abstract: An absorbent hygienic article (1) for absorbing body fluids, the article comprising a liquid permeable topsheet (2), a backing layer (3) and an absorbent core (4) arranged between the topsheet (2) and the backing layer (3), the topsheet (2) and the backing layer (3) being made from roll materials. The topsheet (2) and/or an absorbent layer (4') in the absorbent core (4) is constituted by a cellulosic fibrous web, the fibres in the cellulosic fibrous web being constituted by a mixture of cellulose fibres comprising regenerated cellulose fibres and/or natural cellulose staple fibres and cellulose pulp fibres, the cellulosic fibrous web being a foam-formed, hydroentangled fibrous web.
Patent MX-2022009197-A (MX)
Title: Methods of treatment for alpha-1 antitrypsin deficiency.
Inventor: KUMAR SANJEEV
IPC: A61K31/4162
Filed: 2021-01-29
Abstract: This application describes methods of treating alpha-1 antitrypsin deficiency (AATD) comprising administering Compound I, a deuterated derivative thereof, and/or a pharmaceutically acceptable salt thereof. The application also describes pharmaceutical compositions comprising Compound I, a deuterated derivative thereof, and/or a pharmaceutically acceptable salt thereof.
Patent MX-2022010761-A (MX)
Title: Apparatus for an aerosol generating device.
Inventor: MOLONEY PATRICK
IPC: A24F40/465
Filed: 2021-03-04
Abstract: An apparatus for an aerosol generating device includes an inductive heating circuit (150) configured to inductively heat a susceptor arrangement arranged to heat an aerosol generating material, to thereby generate an aerosol. The inductive heating circuit includes an inductive element (158) configured to inductively heat the susceptor arrangement when a varying current flows through the inductive element, and a switching arrangement (180) for causing the varying current to flow through the inductive element when a first DC voltage is supplied to the inductive heating circuit (150). A voltage regulator (154) is configured to receive an input voltage from a voltage supply (104) and output the first DC voltage across the inductive heating circuit. A control arrangement (106) is configured to adjust the first DC voltage output by the voltage regulator, thereby to adjust a power supplied to the heating circuit (150) for heating the susceptor arrangement. An aerosol generating system and a method of operating an aerosol generating system are also provided.
Patent MX-2022012591-A (MX)
Title: Material shaping method and shaped products.
Inventor: WELLS FELIX HUGO
IPC: C08J9/228
Filed: 2021-04-08
Abstract: The present invention relates to a method of shaping material having a plurality of interstices (such as a network of voids) and shaped products formed by the method. In preferred embodiments the material is a foam such as a polyurethane foam. The shaping method allows such materials to be shaped using contour-shaping machining methods including computer numerical control (CNC) milling, which is provided by way of example only. To be contrasted with methods of manufacturing a shaped material (such as by the polymerisation of a solution or emulsion of monomers), in several aspects the present invention contemplates the shaping of existing (preformed) materials having a plurality of interstices, such as a network of voids.
Patent MX-2022013423-A (MX)
Title: A filter plate assembly for a horizontal plate and frame -type filter, such as a tower press, a filter plate and a vat liner.
Inventor: VÄNTTINEN KARI
IPC: B01D25/127
Filed: 2020-06-03
Abstract: The present disclosure concerns a filter plate assembly (1) which is resistant to both wear and deformation caused by creeping, while facilitating maintenance thereof. The disclosure is based on the idea of providing a filtrate vat (4) formed on, and integral with the filter plate (2), in addition to a separate, replaceable vat liner (5). In this way, a rigid 5 structure of the filtrate vat (4) capable of resisting deformation may be achieved, while the vat liner (5) separates the filtrate from the filtrate vat (4) and the associated filter plate (2), providing wear resistance and facilitating maintenance. The present disclosure further concerns the filter plate (2) and the filtrate vat (5).
Patent MX-2022015718-A (MX)
Title: Synthesis of (2s,5r)-5-(2-chlorophenyl)-1-(2'-methoxy-[1,1'-biphe nyl]-4-carbonyl)pyrrolidine-2-carboxylic acid.
Inventor: DUTHEUIL GUILLAUME
IPC: A61P29/00
Filed: 2021-06-10
Abstract: The present invention relates to a process of manufacturing of (2S,5R)-5-(2- chlorophenyl)-1-(2'-methoxy-[1,1'-biphenyl]-4-carbonyl)pyrrolid ine-2-carboxylic acid (1), including the preparation of (2S,5R)-methyl 5-(2-chlorophenyl)pyrrolidine-2- carboxylate hydrochloride (6.HCl) as intermediate of synthesis:.
Patent MX-NL05000058-A (MX)
Title: Reimbursable life insurance.
Inventor: MONTELLANO RICARDO ANTONIO GAR
IPC: G06M1/00
Filed: 2005-07-14
Abstract: So far, life insurance companies do not include a product having the alternative to refund the insuree part or the total amount of the premiums paid during the policy term as a distinctive characteristic thereof. The present invention is a novel product in the life insurance field, which includes the novel characteristic with regard to the state-of-the-art insurance products of allowing the insuree and/or insurance company to be paid part or the total amount of the premiums whether the insuree is alive until the policy matures or in the event of premature death. The present life insurance includes a term insurance and an endowment insurance, which are particularly combined according to the calculated term and age so as to determine the assured amount of the endowment insurance along with the fraction to be paid of the premiums sum of both insurances, including additional benefits if established during the insurance term.
Patent MX-PA00008000-A (MX)
Title: Thin sanitary napkin capable of controlled deformation when in use.
Inventor: ZULFIKAR MURJI
IPC: A61F13/15
Filed: 2000-08-16
Abstract: The present invention provides a sanitary napkin that is thin (less than 5 mm in thickness), highly absorbent and has a lateral flexibility allowing for controlled deformation when in use, namely the assumption of a "W" pattern (good for absorption performance) or a "M" pattern (which enhances comfort). This controlled deformation provides a good comfort potential and simultaneously reduces the likelihood of bunching due to compression forces exerted laterally against the napkin by the thighs of the wearer. In a specific example, the sanitary napkin is characterized by a lateral stiffness of not less than about 400 g and comprises a cover layer, a barrier layer and an second absorbent layer having at least one preferential bending zone which allows the napkin to adopt a certain three-dimensional deformation profile in response to lateral compression.
Patent MX-PA01000224-A (MX)
Title: Expression of functional eukaryotic proteins.
Inventor: ARNOLD FRANCES H
IPC: C12N15/10
Filed: 1999-07-28
Abstract: This invention relates to the improved expression of evolved polynucleotide and polypeptide sequences encoding for eukaryotic enzymes, particularly peroxidase enzymes, in conventional or facile expression systems. Various methods for directed evolution of polynucleotide sequences can be used to obtain the improved sequences. The improved characteristics of the polypeptides or proteins generated in this manner include improved folding, without formation of inclusion bodies, and retained functional activity. In a particular embodiment, the invention relates to improved expression of the horseradish peroxidase gene and horseradish peroxidase enzymes.
Patent MX-PA01000660-A (MX)
Title: Preparations of tanning/ retanning agents.
Inventor: MARTIN KLEBAN
IPC: C14C3/02
Filed: 2001-01-18
Abstract: Solid composition comprises a compound(s) increasing the shrinkage temperature of an uncured surface by at least 10 degrees C on treatment in water at 20-50 degrees C and a polymer compound(s) with 10-80 wt.% 2-40C alkyl units and with 1-10 mol./kg acid groups, preferably carboxylic and/or carboxylate groups. Solid composition comprises: (A) a compound(s) increasing the shrinkage temperature of an uncured surface by at least 10 degrees C on treatment in water at 20-50 degrees C; (B) a polymer compound(s) with 10-80 wt.% 2-40C alkyl units and with 1-10 mol./kg acid groups, preferably carboxylic and/or carboxylate groups; and optionally (C) additives. An Independent claim is also included for the preparation of the above compositions by adding an aqueous suspension and/or solution of (B) to (A) and optionally (C).
Patent MX-PA01012752-A (MX)
Title: Ocular tension lowering composition for topical adminstration.
Inventor: YOKOYAMA TOMIHISA
IPC: A61K31/41
Filed: 2000-06-09
Abstract: A composition for topical administration exhibiting an excellent ocular tension lowering effect, which contains an angiotensin II antagonist, a borate, and an ethylenediaminetetraacetate.
Patent MX-PA02003777-A (MX)
Title: Catheter introducer assembly comprising needle protection.
Inventor: MENZI THOMAS
IPC: A61M25/06
Filed: 2002-04-15
Abstract: A catheter introducer assembly (10) is disclosed whereby the safety spring clip (20) moves into position to block the needle tip (26) occurs as a direct consequence of the withdrawal of the needle from the catheter bore. The catheter introducer assembly according to the present invention comprises a needle (12) and a needle hub (14), a catheter (16) and a catheter hub (18), and a safety spring clip assembly (20). The safety spring clip assembly (20) being designed to permit the needle (12) to slide inside the spring clip assembly (20) until the needle stop (50) located on the needle meets the proximal wall (58) to thereby prevent further movement of the safety spring clip (20). <IMAGE>
Patent MX-PA02004902-A (MX)
Title: Hydraulic tool having mechanical actuator with internal bypass valve.
Inventor: JOHN D LEFAVOUR
IPC: F15B7/04
Filed: 2002-05-16
Abstract: A hydraulic compression tool having a frame, a hydraulic fluid reservoir on the frame, a ram movably connected to the frame, a conduit system in the frame between the reservoir and the ram, a pump provided in the conduit system, a mechanical actuator provided in the conduit system for contacting the ram, and a bypass valve in the conduit system between a rear end of the ram and a channel of the conduit system to the rear end of the mechanical actuator. The conduit system is adapted to conduit fluid from the pump against both the rear end of the ram and a rear end of the mechanical actuator. The bypass valve is located, at least partially, in a housing member of the mechanical actuator.
Patent MX-PA02008945-A (MX)
Title: Method and apparatus for simultaneous recording and displaying two different video programs.
Inventor: CARLSGAARD ERIC STEPHEN
IPC: H04N5/45
Filed: 2001-03-08
Abstract: A method and apparatus for simultaneously recording and displaying video signals from two different video sources. The apparatus comprises a main channel processing circuit (148), a second channel processing circuit (150), and common circuitry (152). The common circuit comprises a digital video decoder pipe (112) that decodes both first and second encoded video signals. A PIP picture is produced using a common reference clock that is derived from the first video signal. In a record mode, a second channel clock reference is coupled to the second channel processing circuit to produce a recordable signal using a digital encoder. The recordable signal also forms a PIP picture that is coupled to the main channel processing circuit to produce a PIP picture that is used to monitor the recording process.
Patent MX-PA02008962-A (MX)
Title: Method and device for reducing harmonics in power converters.
Inventor: BOUSAADA JOHNNY
IPC: H02M1/12
Filed: 2001-03-13
Abstract: The invention concerns multistage power switching electronic device for reducing undesirable harmonics amplitudes generated in said device, in particular in the form of beats, comprising at least an input filter (1), a rheostatic braking chopper (2) including at least two switches (Fr1, Fr2) and mutlilevel static converter (4) including at least four switches in series (T1, T2, T3, T4). The invention is characterised in that the oscillator (4) is directly attached to the chopper (2) providing a connection by their midpoint (X = X ) and it comprises a variable random frequency pulse generator controlling the switches of said chopper (2).
Patent MX-PA02009302-A (MX)
Title: Absorbent composite having surface dryness.
Inventor: GRAEF PETER A
IPC: D21F11/04
Filed: 2001-03-23
Abstract: The present invention provides an absorbent composite having improved surface dryness. The composite has three strata with adjacent strata separated by a transition zone. The composite s first stratum includes synthetic fibers and provides the composite with improved surface dryness. Methods for forming the composite and absorbent articles that incorporated the composite are also provided.
Patent MX-PA02011673-A (MX)
Title: Maize glutamine synthetase gene promoter.
Inventor: MUHITCH MICHAEL J
IPC: A01H5/00
Filed: 2001-05-23
Abstract: The present invention provides the transcription regulatory region for the GS1-2 gene. The GS1-2 transcription regulatory region effectively drives the pedicel-specific expression of an operably linked gene. Thus, the disclosed transcription regulatory region provides an invaluable tool for affecting seed assimilation and development and for increasing fungal and disease resistance. Recombinant DNA constructs and methods for affecting seed development and disease resistance are provided.
Patent MX-PA02012560-A (MX)
Title: Compounds to treat alzheimer s disease.
Inventor: JOHN VARGHESE
IPC: A61K9/06
Filed: 2001-06-29
Abstract: The present invention is substituted amines of formula (XV) useful in treating Alzheimer s disease and other similar diseases.
Patent MX-PA03006754-A (MX)
Title: Desk and desking system.
Inventor: STEVEN BROOKS
IPC: G06F/
Filed: 2002-01-28
Abstract: A desk and desking system, each desk being adapted for connection to another desk as part of a network of desks, each desk comprising: a desktop comprising sides, a bottom-face, and a work surface on the top side of the desktopK desktop support means; a chassis comprising one or more cassettes containing one or more electronics systems; a power distribution system and an electronics conncetions system, both mounted beneath the desktop and within the chassis and extending from one side of the desktop to another, connectable to at least one cassette and connectable to similar adjacent desks at one or more sides.