baber/WOPTO huggingface dataset:
Patent GB-1325797-A (GB)
Title: Medicines comprising cytidine derivatives
IPC: C07H19/06
Filed: 1971-08-17
Abstract: 1325797 Antineoplastic &c medicines UPJOHN CO 17 Aug 1971 [24 Sept 1970] 38573/71 Heading A5B Compositions for the treatment of neoplasms, autoimmune diseases, tissue rejection, viral diseases trichomonal and fungal infections comprise a carrier and the compound (or a salt thereof) 2,2'-anhydro-ara-cytidine having the formula: They may be in conventional dosage unit forms comprising 1 mg to 1 gm of the active compound per unit. Optionally, there may also be present additional active compounds such as antibiotics, e.g. tetracycline, chlortetracycline, penecillin, novobiocin, neomycin, actinomycin C & D, nystatin, amphotericin B and trichomycin; hormones, e.g. diethylstilbestrol, progesterone, medroxy progesterone, estradiol, fluoxymesterone and methyltestosterone; alkylating agents, e.g. busulphan, chlorambucil cyclophosphamide, mechlorethamine hydrochloride, thio-Tepa, triethylene melamine and 5-[bis-(2-chloroethyl) amino] uracil. The invention includes methods of treating neoplasms in non-human animals with the compounds of compositions of the invention.
Patent GB-1332201-A (GB)
Title: Alkylated diphenylamines
IPC: C09K15/18
Filed: 1971-01-26
Abstract: 1332201 Alkylated diphenylamines CIBAGEIGY (UK) Ltd 25 Jan 1972 [26 Jan 1971] 3159/71 Heading C2C [Also in Division C5] The invention comprises compounds of formula in which R 1  is a C 1 -C 4  alkyl group, R 2  is methyl and R 3  is a cycloalkyl or cycloalkenyl radical having 5-12 carbon atoms being either unsubstituted or substituted with an alkyl group, or in which R 2  and R 3 , together with the carbon atom to which they are attached form a carbocyclic ring system having from 5 to 12 carbon atoms in the ring, the ring being either unsubstituted or substituted with an alkyl group. The compounds are prepared by alkylating diphenylamine with an appropriate olefin, cyclopropane or cyclobutane in the presence of a Friedel Crafts catalyst which may be a Lewis acid (e.g. AlCl 3  or ZnCl 2 ) or a Bronsted acid (acid washed Montmorillonite), the reaction being carried out preferably by heating in the presence of an inert organic solvent. The compounds of the invention are useful as antioxidants for a wide variety of listed organic materials especially synthetic lubricants. Examples of the compounds of the invention are p,p<SP>1</SP> - di - (1 - methylcyclohexyl)diphenylamine, p,p<SP>1</SP> - di - (1 - methyl - 4 - isopropylcyclohex - 1- enyl - 4)diphenylamine, p,p<SP>1</SP> - di - (2 - methyl- 4 - isopropylcyclohex - 1 - enyl - 4)diphenylamine, p,p<SP>1</SP> - di - (2 - methyl - 3 - isopropylcyclohex - 1 - enyl - 3)diphenylamine, p,p<SP>1</SP> - di- (1 - isopropyl - 4 - methylcyclohexyl)diphenylamine, p,p<SP>1</SP> - di - (1 - isopropyl - 3 - methylcyclohexyl)diphenylamine, p,p<SP>1</SP> - di[α - methyl - (1- methylcyclohexen - 1 - yl - 4)ethyl]diphenylamine and p,p<SP>1</SP> - di - (1 - methyl - 4 - isopropenylcyclohexyl)diphenylamine.
Patent GB-1338575-A (GB)
Title: Building elements formed from timber beams
IPC: E04B2/70
Filed: 1971-05-21
Abstract: 1338575 Timber beams DAVID GRAY (CONTRACTORS) Ltd 21 May 1971 39966/72 Divided out of 1338573 Heading E1B [Also in Divisions B4 and B5] A building element comprises a timber beam provided at one edge portion 2 with one or more longitudinally extending grooves 3, and at the other edge portion 1 with a complementary configuration of one or more longitudinally extending tongues 4. At least one of the edge portions 1, 2 is further provided with one or more longitudinally extending cuts 5 or 6 substantially deeper and narrower than the or each groove. The edge portions 1, 2 are joined by longitudinally extending faces which in the transverse section of the beam are convex. As described a plurality of the elements may be engaged side-to-side to form a building structure, e.g. a wall or roof. The element may include a slot 8 and transverse recesses 9 with bevelled edges 10 to enable two such elements to be interengaged at right angles to each other.
Patent GB-1340328-A (GB)
Title: Pallets
IPC: B65D19/00
Filed: 1971-04-19
Abstract: 1340328 Load handling pallets IMPERIAL CHEMICAL INDUSTRIES Ltd 19 April 1971 [19 Feb 1970] 8051/70 Heading B8H An expandible pallet comprises a foam laminate of the kind comprising a layer of rigid synthetic plastics foam, e.g. a polyurethane confined between two skins, the laminate having near two opposing edges thereof, a plurality of substantially parallel slits, U-shaped crimps or notches (hereinafter termed "slits"), each extending from one face of the laminate towards its other face, the laminate being folded about the inner ends of the slits, so that the folded edge portions underlie and support the edges of the unfolded inner portion of the laminate. In a preferred embodiment, the slits in each plurality of slits are equidistant from each other, to provide each edge of the laminate with a plurality of foldable portions 4a, 4b, 4c and 4d of equal width, the first 7a and subsequent alternate slits 7c extend downwardly from the upper face to just short of the lower face of the laminate and the second 7b and subsequent alternate strips 7d extend similarly but in the opposite direction, the first foldable portion 4a being folded downwardly and inwardly through 180 degrees to underlie the edge of the unfolded portion of the laminate, and each subsequent foldable portion being folded through 180 degrees in the opposite direction from the immediately preceeding foldable portion, the folded portions being optionally secured to each and to the overlying lower face of the unfolded portion of the laminate, e.g. by an adhesive or by stapling. In an alternative embodiment, there are three slits in each plurality of parallel slits, the first two of which 7x and 7y extend upwardly from the lower face towards the upper face of the laminate and the third of which 7z extends in the opposite direction, the first foldable portion 4x being folded either substantially vertically downwards or inwardly and downwardly through an obtuse angle, the second foldable portion 4y being folded inwardly and upwardly towards the lower face of the laminate and the third foldable portion 4z being folded outwardly, the angle of slits and/or the lengths of the first and second foldable portions being selected that the third foldable portion, after folding, is substantially horizontal and underlies and supports the overlying lower face of the unfolded portion of the laminate to which it may be secured, e.g. by an adhesive or by stapling.
Patent GB-1341192-A (GB)
Title: Radio telephony systems
IPC: H04B7/08
Filed: 1971-04-19
Abstract: 1341192 Diversity reception systems PYE Ltd 19 April 1971 [5 Feb 1970] 5517/70 Heading H4L An arrangement is provided for selecting which of a number of radio-receivers receiving the same information is receiving the signal with the highest signal to noise ratio. Each receiver 1 produces a current dependent on the signal to noise ratio and a coder 3 produces a signal whose frequency (in the range 2À7-3À0 kHz), is dependent on the signal to noise ratio dependent current. This quality signal is combined with the audio frequency received signal passed through a 2À5 kHz low-pass filter 2 and is transmitted to a central station, each receiver being connected to one of the fixed contacts of each of switches 5 and 13. The moving contact of switch 5 is continuously stepped cyclically by pulses from a scan control 7, the output being passed through a band pass filter 8 which passes the quality signal. The frequency of the quality signal is converted to a voltage in 10 and passed to a compare and hold circuit 11. Circuit 11 includes a capacitor which is charged to and maintains the highest voltage from 10, i.e. corresponding to the highest signal to noise ratio. When the capacitor in circuit 11 is charged an output pulse is passed to select control 12 which sets switch 13 to receive signals from the same receiver as switch 5, the signals then being passed through a low pass filter 14. The output pulse from circuit 11 is also passed to scan control 7 which causes a pulse to discharge the capacitor of circuit 11 immediately before the step of switch 5 to the contact through which the capacitor was charged in the previous cycle of switch 5. A call store 16 comprising a plurality of monostable circuits operates a plurality of lamps to show which receivers are receiving signals. To reduce the effect of transients due to the switch 5, bandpass filter 8 may include transistors which, at the time switch 5 is moved, gate resistors into the filter circuit to reduce the Q of the filter. The switches 5 and 13 may be electronic and may be formed as electronic circuits. For a larger number of receivers a number of central stations may be used, filters 14 then not being included and the resulting signals being fed to one central station as shown.
Patent GB-1347447-A (GB)
Title: Sail rig
IPC: B63H9/06
Filed: 1972-08-25
Abstract: 1347447 Sail rigs E F HISCOCK 25 Aug 1972 39748/72 Heading B7V In a sail rig for a sail propelled vehicle the sail head is pivotally supported in an elevated position above the vehicle, the tack 38 of the sail may be positioned along an arc centred at a point on the vehicle substantially vertically below the sail head pivot point, and the clew 39 may be positioned along an arc centred on the tack. In a preferred embodiment, the luff 33 of a boat sail 31 is stiffened by a luff spar 36 the upper end of which is attached to a pivot 46 supported by a mast 44 and the lower end is fixed to a thrust boom 55 which is pivoted to a pulpit 59 on the boat vertically below the pivot 46. The foot of the sail is fastened to a boom 37 which is pivotally mounted on luff spar 35 as by U-shaped strap 40. The sail 31 is raised by halyard 71 which together with downhaul 77 controls the sail tension. A boom vang 83 may provide further downpull on the boom. Main sheet 87 is rigged in a conventional manner for positioning the free end of the boom, while the non-conventional rigging comprises a pair of fore sheets 95<SP>1</SP>, and an elastic retraction line 101 for the purpose of positioning thrust boom 55. The mast 44 is bifurcated at its lower end to allow for movement of tiller 18.
Patent GB-1349418-A (GB)
Title: Adjustable mortar board
IPC: A47B9/20
Filed: 1972-02-23
Abstract: 1349418 Adjustable tables F S WAGLAND 19 Feb 1973 [23 Feb 1972] 8274/72 Heading A4H A mortar board for bricklayers comprises a tubular upright (a) mounted on feet (b) welded thereto, a tube (c) telescoping within the upright (a), a pin or bolt (f) engaging a hole (d) in the upright and a selected hole (e) in the tube to secure the tube at the desired height, and flats (g) welded at their intersection to tube (c) and to a table top (h).
Patent GB-1353588-A (GB)
Title: Spark igition systems
IPC: F02P3/08
Filed: 1970-05-21
Abstract: 1353588 Pulse generators JOSEPH LUCAS (INDUSTRIES) Ltd 10 May 1971 [21 May 1970] 24601/70 Heading H2A [Also in Division F1] A pulse generator for controlling an ignition system includes a rotor 81 which is driven by an engine shaft and a mounting bracket 82 carrying a permanent magnet 83 from which extends a magnetic core 84 surrounded by a winding 85. The rotor is shaped to produce a desired wave form having two slopes indicated in Fig. 3 (not shown) by dotted lines A and B (see also Division F1).
Patent ID-29604-A (ID)
Inventor: DAVIS GERALD C
IPC: H04M1/724
Filed: 1999-07-07
Abstract: A control apparatus for a hand-held wireless telephone having a housing and operating in a first operational state of a plurality of sequential operational states. The control apparatus changes the operational state of the wireless telephone from the first operational state to a second operational state. The control apparatus itself comprises a detector that produces a signal responsive to a user grasping the housing of the wireless telephone and a controller responsive to receiving the signal produced by the detector and configured to select another operational state following the first operational state in a predetermined sequence of operational states.
Patent ID-29553-A (ID)
Inventor: BELLUSSI GIUSEPPE
IPC: C07C1/04
Filed: 2001-03-01
Abstract: A supported cobalt-based catalyst is described, characterized in that the carrier has an average particle diameter, measured by means of Coulter LS230, ranging from 70 to 250  mu m, a surface area higher than 175 m<2>/g and a pore volume higher than 0.35 m<3>/g, measured with the B.E.T. method. The above catalyst is particularly useful in the Fischer-Tropsch reaction. <IMAGE>
Patent IL-104460-A (IL)
Title: 3'-derivatized oligonucleotide analogs with nonnucleotidic groupings, their preparation and use
IPC: A61K31/70
Filed: 1993-01-20
Abstract: Oligonucleotide analogs (I) and their physiologically tolerable salts. Oligonucleotide analogs and their physiologically tolerable salts of formula (I) are new. R<1> = H, a substituent or -P(=W)ZZ'; R<2> = H, OH, 1-18C alkoxy, halo, azido or amino; B = nucleotide base residue; A = oxy or methylene; d, e, f = 0-50; i = 1-10; r = 0 or 1; W = oxo, selenoxo or thioxo; V = oxy, sulfandiyl or imino; Y = oxy, sulfandiyl, imino or methylene; Y' = oxy, sulfandiyl, imino, (CH2)m or V(CH2)m; m = 1-18; X = OH or SH; U, R<3>, R<4> = substituents; p = 1-100; q = 0-18; R<11> = H or functional group; Sp = a (3',5'-) spacer group of formula (i); g, g' = 0 or 1; h = 0-10; G = 1-12C alkylene (optionally substituted), (6-14C)aryldi-(1-8C)alkylene, 6-18C arylene, (CH2CH2V) alpha CH2CH2, (CH2V) alpha CH2, -(G-Y-P(=W)(U)-Y'-) beta  or a group of formula (ii);  alpha  = 1-11;  beta  = 1-6; Z, Z' = OH, (seleno)thio or a substituent; provided that r is 0 when V is Y' and is 1 if i is greater than 1. Positions of R<2> and the adjacent phosphoryl residue can be reversed; each nucleoside had D- or L-configuration and each B has alpha  or  beta  configuration. Independent claims are also included for: (1) a method for producing (I); (2) the phosphitylation reagent of formula DMTr-X'-G'-Y''-P(U')(NR<5>R<6>); and (3) a pharmaceutical composition containing at least one compound (I) and optionally auxiliary, carrier and/or other active agents. R<5>, R<6> = 1-12C alkyl or together form a 5-6 membered ring; DMTr = dimethoxytrityl; X', Y'' = oxy or sulfandiyl; U' = 1-4C alkyl or protected OH; G' = (CH2CH2O) alpha CH2CH2 or CH2CH(OR')CH2; and R' = 1-18C alkyl, 6-14C aryl or 6-14C aryl(1-8C) alkyl.
Patent IL-104880-A (IL)
Title: Pharmaceutical composition comprising antigen for autoimmune diseases suppression
IPC: A61K38/095
Filed: 1993-02-26
Abstract: A pharmaceutical oral composition for treating an autoimmune disease in a human, the composition comprising: an effective amount for treating said disease of a bystander antigen, said antigen upon administration eliciting T cells that are targeted to the area of autoimmune attack in said disease and that suppress immune cells in said area contributing to said autoimmune attack; and a pharmaceutically acceptable carrier or diluent; wherein said bystander antigen is specific to an organ or tissue afflicted by Immune attack during said disease, further wherein said bystander antigen is not an autoantigen or fragment thereof, further wherein said composition is substantially free of autoantigens, further wherein said bystander antigen, when administered in said composition, is not effective to treat said disease hormonally.
Patent IL-108297-A (IL)
Title: Connection and tap sleeve for coaxial cables or the like
IPC: H02G15/08
Filed: 1994-01-07
Abstract: In a connection and tap sleeve for coaxial cables or the like in wideband networks, with a sleeve body closing tightly in the operational position with cable inlets and cable outlets, and with a printed circuit board mounted inside the sleeve body with branch circuit connections for splicing and/or distribution, and where the damping values of the branch circuit connections can be altered, it should be possible to wire up all outlets simply at any damping value required. This is achieved in that the sleeve body (1) is formed so that it can be opened and tightly closed again and the printed circuit board (5) has an individual line disconnection for each tap, discharging into plug connections (19), a modular structured transfer element (20) with a pre-set, selectable damping value, provided with corresponding plug connections (21), being plugged interchangeably into the plug connections (19).
Patent IL-113246-A (IL)
Title: Bisphosphonates and pharmaceutical compositions containing them
Inventor: BREUER ELI
IPC: A61K38/00
Filed: 1995-04-04
Abstract: A compound of the formula or a salt thereof wherein X=H, OH n is an integer of 2 or 3, m is an integer of 2 or 3, R is trhe side chain of a naturally-occurring amino acid, and R1 is H, or R and R1 together with the NH-CH to which they are bonded represent the pyrrolidine group of proline. 2200 י" ד באלול התשס" ד - August 31, 2004
Patent IL-115493-A (IL)
Title: Derivatives of esters and amides of carbolinyl- carbazolyl- cycloalkano-indolyl-and azaindolymethyl-benzeneacetic acid their preparation and pharmaceutical compositions containing them
IPC: C07D471/04
Filed: 1995-10-02
Abstract: Cycloalkano-indole derivs. and aza analogues of formula (I) and isomers and salts are new. R1-C=C-R2 = phenyl, pyridyl or a gp. of formula (a), all opt. substd. by 1-3 gps. R'; R8 = H or 1-4C alkyl; R3-C=C-R4 = phenyl, 4-8C cycloalkene or 4-8 membered oxocycloalkane (all opt. substd. by 1-3 gps. R'); R' = independently halo, CF3, COOH, OH, up to 6C alkoxy carbonyl, 1-6C alkoxy, or 1-6C alkyl (opt. substd. by OH or 1-4C alkoxy); R = H, 4-12C cycloalkyl or 1-12C alkyl; A = CO or CS; X = O, S or NR9; R9 = H or 1-6C alkyl (opt. substd. by OH or phenyl); R5 = phenyl or 5-8 membered, opt. unsatd. heterocyclic with 1-3 heteroatoms (S, N and/or O), (both opt. mono- to tri-substd. by NO2, COOH, halo, CN, 2-6C alkenyl, 1-6C alkoxy or alkyl (opt. substd. by OH, COOH, 1-6C alkoxy or up to 6C alkoxycarbonyl; and/or opt. mono- substd. by OR10 or NR11R12); R10 = H, 1-6C alkyl or 2-6C alkenyl; R11, R12 = H, phenyl, 1-6C alkyl, or up to 8C acyl (opt. subst. by NR13R14); R13, R14 = H or up to 8C acyl; R7 = H; R6 = H, COOH, 1-5 alkoxy, or 1-6C alkyl (opt. substd. by OH or OCOR15); or R6+R7 = O; R<15> = phenyl (opt. mono- to tri-substd., by halo, OH or 1-5C alkyl), or 1-22C alkyl or 2-22C alkenyl (both opt. substd. by OR16); R16 = H, benzyl, triphenylmethyl or up to 6C acyl. Also claimed are intermediates of formula (II).
Patent IL-126459-A (IL)
Title: Mixtures of pyrimethanil or pyrimethanil salts with an organic acid and their use as fungicides
IPC: C07D239/42
Filed: 1997-04-25
Abstract: Fungicidal product (I) obtained by combining pyrimethanil with an organic, acid having a volatility of  2Pa at 20  deg C, is new.
Patent IL-126924-A (IL)
Title: Plant containing composition for treating herpes virus and other infectious diseases
IPC: A61K38/28
Filed: 1997-03-12
Abstract: A composition for treating microbial infections comprises antimicrobial isolates from at least a part of the following plants; Echinacea purpurea, E. angustifolia, E. pallidae, E. vegetalis, E. atribactilus, Pimpinella anisum, myroxylon, arctostaphylox, carum, capsicum, Eugenia mytacea, coriandrum, inula, allium, gentiana, juniperus, calendula, origanum, mentha labiate, commiphora, plantago, rosmarinus, ruta, laptisa, artemisa, sage, mentha, parthenium, integrifolium, eucalyptus, asteriacea and their cultivars. Also claimed is a method for treating herpes simplex or other infectious disease, by topical application of a composition containing 2-90 % of a phytochemical concentrate of E. purpurea and E. angustifolia, containing echinacen; echinacen B; echinaceine; echinacoside; caffeic acid ester; echinolone; enzymes; glucuronic acid; inulin; inuloid; pentadecadiene; polyacetylene compounds; polysaccharides; arabinogalactan; rhamnose; tannins; PSI (a 4-O-methylglucoronoarabinoxylan, Mr 35kD) and PS II (an acid rhaminoarabinogalactan, Mr 450 kD), cynarin; 1,5-di-O-caffeoylquinic acid, chicoric acid; 2,3-O-di caffeoyltartaric acid; borneol; bornyl acetate; pentadeca-8(Z) en-zone; germacrene D; caryophyllene; caryophyllene epoxide; anthocyanin, pyrolizidine alkaloid, lipophilic amide; isobutylamide; polyacetylene; anthocyanin; 3-O-B-D glucopyranoside; 3-O-(6-O-malonyl-B-D-glucopyranoside); tussilagine; isotussilagine; isomeric dodeca-isobutylamide; tetraenoic acid; and/or carophylenes; and 0.005 - 0.8 % quat. ammonium salt surfactants comprising alkyl dimethylbenzylammonium chloride, dimethylbenzylammonium chloride, benzalkonium halide, alkylbenzyldimethyl ammonium chloride, dialkyldimethyl ammonium chloride, diisobutylphenoxyethoxyethyl dimethylammonium chloride and o-benzyl-p-chlorophenol; and sterile water in ratio water to phytochemical concentrate and surfactant of 2-100:1. The composition is maintained on the infected area for 1-30 hours, during which period the physical symptoms are substantially resolved.
Patent IL-127162-A (IL)
Title: Kidney injury related molecules
IPC: C07K14/47
Filed: 1997-05-23
Abstract: Purified and isolated DNA molecule (I) having the 2566, 2084, 2303 or 1795 bp nucleic acid sequence given in the specification, is new.
Patent IL-137137-A (IL)
Title: Rotary flow-path exchanging valve
IPC: F16K/
Filed: 1998-06-23
Abstract: A rotary flow-path exchanging valve (100) comprising: a cylindrical valve housing (1); a valve seat plate (5) having a low pressure side port (15) secured to said valve housing and connected to a low pressure side conduit (13), a high pressure side port (19) connected to a high pressure side conduit (17) and an exchanging port (27); a valve element (3) rotatably provided within said cylindrical valve housing and movably provided in a rotary axial direction thereof, said valve element being brought into contact with said valve seat plate in its one end surface (33) so that said exchanging port is selectively communicated with either one of said low pressure side port and said high pressure side port by rotation; a pilot valve (9), defined on the side of the other end surface opposite to the one end surface of said valve element, for selectively communicating a pressure chamber (41) into which pressure at the high pressure side port is introduced with said low pressure side port; an electromagnetic solenoid (11) for rotating said valve element and opening/closing said pilot valve, said valve housing comprises a first guiding cylinder (39) for movably supporting said pilot valve in the rotary axial direction and a second guiding cylinder (6) for supporting said valve element, displaced from said first guiding cylinder in the rotary axial direction; said valve element includes a guiding member (4) protruding, in the rotary axial direction, from the other end surface located on the side of said pilot valve and partially abutting on the inner periphery of said valve element guiding cylinder in the peripheral direction, whereby when said valve element moves in the rotary axial direction, said guiding member abutting on the inner periphery of said valve element guiding cylinder slides in the rotary axial direction on the inner periphery of said valve element guiding cylinder. 345 ו' בניסן התשס" ד - March 28, 2004
Patent IL-148068-A (IL)
Title: Use of alpha- lipoic acid or derivatives thereof as an active ingredent in the manufacture of medicaments for treating or preventing migraine
Inventor: SCHOENEN JEAN
IPC: A61K31/385
Filed: 2002-02-06
Abstract: The invention relates to the use of racemic alpha-lipoic acid or its enantiomers or pharmaceutically acceptable salts, amides, esters or thioesters thereof, in reduced or oxidized form, as active ingredient in the prevention or the acute or chronic treatment of migraine.
Patent IL-148932-A (IL)
Title: Inhibitors of ??l??2 mediated cell adhesion
Inventor: SIRCAR ILA
IPC: A61K31/5377
Filed: 2002-03-27
Abstract: The present invention relates to a compound of formula: (I), or a pharmaceutically acceptable salt thereof.