baber/WOPTO huggingface dataset:
Patent NZ-581304-A (NZ)
Title: Modified release solid or semi-solid dosage forms
Inventor: LEE DER-YANG
IPC: A61K9/26
Filed: 2008-06-09
Abstract: Disclosed is a solid or semi-solid pharmaceutical dosage form comprising: a) a first portion containing a first active ingredient comprised of an NSAID and/or a pharmaceutically acceptable salt thereof, wherein the first active ingredient is released from the dosage form in a substantially immediate manner upon contact of the dosage form with a dissolution medium; and b) a second portion containing i. particle cores comprised of a second active ingredient, which is different from the first active ingredient; ii. a semi-permeable coating layer substantially covering said particle cores to form coated particles; and iii. a protective coating layer substantially covering said coated particles, wherein the second active ingredient is released from the second portion in a modified release manner upon contact of the dosage form with the dissolution medium, and wherein the duration of the therapeutic effect of the second active ingredient as released from the second portion of the dosage form is substantially the same as the duration of the therapeutic effect of the first active ingredient. Example of a NSAID is Ibuprofen and an example of a second active ingredient is phenylephrine.
Patent NZ-582786-A (NZ)
Title: Assays for nucleic acids
Inventor: ERMANTRAUT EUGEN
IPC: B01L3/00
Filed: 2008-07-23
Abstract: Disclosed is a device comprising a rigid substrate, a flexible cover element at least partially covering the substrate, a first structure formed in the substrate, adapted for accommodating liquids and adapted for releasing contents of one or more cells, spores, or viruses, the contents including the target molecules, a second structure formed in the substrate, adapted for accommodating liquids and comprising at least one binding member adapted for capturing the target molecules and for determining a value indicative for the presence and/or amount of the target molecules, a microfluidic network interconnecting at least the first structure and the second structure, and an actuator member adapted for effecting a fluid flow between the first structure and the second structure by pressing the flexible cover element against the substrate to selectively close a portion of the microfluidic network.
Patent NZ-584933-A (NZ)
Title: System for controlling multiple computers from one user terminal including detecting data being added to a memory buffer of one of the computers and copying this data to a memory of another of the computers
Inventor: LEIBOW MICHAEL
IPC: G06F3/14
Filed: 2008-10-24
Abstract: Disclosed is a computer management system (100) for interacting with a plurality of host computers (112, 114, 116, 118) from a user console (102). Each host computer (112, 114, 116, 118) includes a memory buffer and a host software program executed thereon. The user console (102) has associated user interface devices including a keyboard (104), a cursor control device (108) and a video display unit (106). The user console (102) also includes a management device (200) operatively connecting the user console (102) to the plurality of host computers (112, 114, 116, 118) via a communications channel. The management device (200) is configured to manage keyboard control signals and cursor control signals transmitted from the user console (102) to the plurality of host computers (112, 114, 116, 118) and buffer incoming video frames received from the plurality of host computers (112, 114, 116, 118). The management device (200) also permits selective manipulation of the incoming video frames and simultaneous display of the incoming video frames from the plurality of host computers (112, 114, 116, 118) on the video display unit (106). The management device (200) includes a management software executable thereon. The selective manipulation of the incoming video frames comprises at least one of adding frames in a time sequence; removing frames from a time sequence; rendering of curves, polygons, and text; filling; rotating; translating; and scaling. The host software program and management software operate together to provide automatic generation of commands to transfer data from a first one of the plurality of host computers to a second one of the plurality of host computers via the communication channel. This is performed by monitoring a first memory buffer of the first one of the plurality of host computers and, upon detecting the data being added to the first memory buffer, copying the data to a second memory buffer of the second one of the plurality of host computers.
Patent NZ-585440-A (NZ)
Title: New therapeutic approaches for treating cmt and related disorders
Inventor: COHEN DANIEL
IPC: A61K31/197
Filed: 2008-11-28
Abstract: Disclosed is the use of a composition comprising at least two compounds selected from D-Sorbitol; Baclofen; Pilocarpine; Naltrexone; Methimazole; Mifepristone, and Ketoprofen, or salts thereof, in the manufacture of a medicament for the treatment of Charcot-Marie Tooth disease.
Patent NZ-587679-A (NZ)
Title: Retaining wall for a sand hill
Inventor: SPRY WILLIAM J
IPC: E02D17/18
Filed: 2006-05-19
Abstract: A hill 80 of sand or similar flowable granular material is contained and partially supported behind the rear face 74 of a wall 70 positioned along the lower portion of the hill. The height of the wall is greater than the height of the hill adjacent the rear face. The wall includes a plurality of horizontal passageways 88 .104 so that the angle of repose of the flowable granular material permits the material to flow toward the front of the passageways adjacent the front face 72 of the wall without substantially discharging from the passageways. However, should the hill collapse somewhat the force exerted by the material against the rear face of the wall is reduced by permitting the flowable granular material to discharge through the passageways and out of the front face onto the ground 76.
Patent NZ-594668-A (NZ)
Title: Humanised antibodies with anti-tumour activity
Inventor: KIENZLE NORBERT ALEXANDER
IPC: A61K39/395
Filed: 2010-03-16
Abstract: Disclosed is a VH binding domain, the binding domain comprising a first framework region, a first CDR1 (SGYSWH), a second framework region, a second CDR2 (HIHX8SGRPTYX9PSLX10S), a third framework region, a third CDR3 (KGKGSDDGLNY) and a fourth framework region. Alternatively disclosed is a VL binding domain, the binding domain comprising a first framework region, a first CDR1 (SASSSLSYIH), a second framework region, a second CDR2 (DTSNLAS), a third framework region, a third CDR3 (FQGSEYPLT) and a fourth framework region. Further disclosed is an antibody comprising two light chains and two heavy chains in which the sequence of the light chains is as shown in SEQ ID NO: 7 and the sequence of the heavy chains is as shown in SEQ ID NO: 94.
Patent NZ-597627-A (NZ)
Title: Feeding apparatus with container in form of dummy with apertures and protrusions that infant can chew on to have solid food forced through apertures
Inventor: LO FU MAN HERMAN
IPC: A61J9/00
Filed: 2010-05-21
Abstract: A feeding apparatus includes a food container (7). The food container (7) includes an open end (71) and a closed end (72). The food container (7) is provided on a surface thereof with a plurality of apertures (8) and a plurality of protrusions which may have the apertures formed therein, or may be separate to the apertures. The food container (7) is made of a resilient material for use with foodstuff, such that an infant can suck food through the apertures but not be in danger of choking.
Patent NZ-598010-A (NZ)
Title: Heat Exchanger
Inventor: WEBB FREDERICK MARK
IPC: F22B37/18
Filed: 2012-02-03
Abstract: 598010 Disclosed is a heat exchanger for transferring or removing heat or energy from a air flow through an air conditioning plant. The heat exchanger comprises a first flow path arranged to contain a first heat exchanging medium and at least one second flow path which surrounds the first flow path. Each of the at least one second flow paths being arranged to contain a second heat exchanging medium for exchanging heat with the first heat exchanging medium. The at least one second flow path is formed through helically winding a single length of conduit around the first flow path, the conduit having at least one channel extending the length thereof which defines the second flow path(s). One or more fins extend from an outer surface of the helically wound length of conduit for facilitating exchange of heat between the second heat exchanging medium and a surrounding air flow. The conduit has a body of elongate cross section and wherein one or more projections extend from an outer elongate wall of the body, such that when the conduit is helically wound around the first flow path the projection(s) form the heat exchanging fin(s). The projections run the length of the conduit body and are integrally formed therewith through an extrusion process.
Patent NZ-619953-A (NZ)
Title: Human cytomegalovirus neutralizing antibodies and use thereof
Inventor: LANZAVECCHIA ANTONIO
IPC: C07K16/08
Filed: 2009-07-15
Abstract: Disclosed is an isolated antibody, or an antigen binding fragment thereof, wherein the antibody or fragment comprises (a) heavy and light chain variable regions having amino acid sequences set forth in SEQ ID NOs: 61 and 62, respectively, or heavy and light chain variable regions having amino acid sequences at least 85% identical to SEQ ID NOs: 61 and 62, respectively, or (b) heavy and light chain variable regions having amino acid sequences set forth in SEQ ID NOs: 29 and 30, respectively, or heavy and light chain variable regions having amino acid sequences at least 85% identical to SEQ ID NOs: 29 and 30, respectively, or (c) heavy and light chain variable regions having amino acid sequences set forth in SEQ ID NOs: 125 and 126, respectively, or heavy and light chain variable regions having amino acid sequences at least 85% identical to SEQ ID NOs: 125 and 126, respectively, wherein the sequences are as defined in the complete specification. Also disclosed is the use of said antibodies for the treatment of hCMV infection.
Patent NZ-631067-A (NZ)
Title: Mineral composition made from a mixed solid phase of calcium and magnesium carbonates, method of preparing same and use thereof
Inventor: LORGOUILLOUX MARION
IPC: C01B32/60
Filed: 2013-03-22
Abstract: Disclosed is a mineral composition made from a mixed solid phase of calcium and magnesium carbonates, method of preparing same and use thereof for use in thermal insulation, wherein the mineral composition contains a mixed solid phase of calcium and magnesium carbonates, formed from a crystallised calcium portion and a crystallised magnesium portion in the form of platelets, the crystals of the calcium portion and those of the magnesium portion being aggregated in the form of composite aggregates, said aggregates themselves being at least partially agglomerated, said calcium portion comprising at least one carbonate chosen from the group consisting of calcite, aragonite and the mixtures thereof, said magnesium portion comprising hydromagnesite in platelet form, said mixed solid phase having a bulk density less than or equal to 250 kg/m3, and greater than or equal to 80 kg/m3, measured according to standard EN 459.2. Also disclosed is a method for manufacturing a mineral composition based on a mixed solid phase of calcium and magnesium carbonates, comprising: -i) preparing at least partly hydrated dolomite by calcining raw dolomite followed by at least partial hydration of the calcined dolomite; -ii) placing the said at least partly hydrated dolomite in suspension in an aqueous phase, this suspension having a proportion of between 5 and 15 % by weight of solid matter relative to the total weight of the suspension, -iii) carbonation of the said dolomite in suspension by injecting a CO2-containing gas into the said suspension heated to a temperature of 55 to 90 °C, at a CO2 flow rate of 2.5 to 15 dm3/min/kg of said solid matter in suspension, with a stepwise reduction in pH of the suspension down to a value below 9 and in parallel and successively a reduction in the electrical conductivity of the suspension, then stabilisation thereof and finally an increase in the stabilised electrical conductivity, carbonation being halted as soon as this increase in electrical conductivity is observed; -iv) obtaining a mixed solid phase of synthetic calcium and magnesium carbonates formed of a crystallised calcic portion and a crystallised magnesium portion in plate-like form, the crystals of the calcic portion and those of the magnesium portion being aggregated in the form of composite aggregates, these aggregates themselves being at least partly agglomerated in the form of agglomerates, the said calcic portion comprising at least one carbonate selected from the group consisting of calcite, aragonite and the mixtures thereof, the said magnesium portion comprising hydromagnesite in plate-like form, the said mixed solid phase of carbonates of said mineral composition having a bulk density equal to or lower than 250 kg/m3 and equal to or higher than 80 kg/m3 measured according to standard EN 459.2.
Patent NZ-714082-A (NZ)
Title: 11-hydroxyl-derivatives of bile acids and amino acid conjugates thereof as farnesoid x receptor modulators
Inventor: PELLICCIARI ROBERTO
IPC: A61P1/16
Filed: 2014-05-14
Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R1 is a hydroxy group and R2, R3, R4, R5, and R6 are as described herein. The present invention relates generally to selective FXR agonists and to methods of making and using them.
Patent NZ-715540-A (NZ)
Title: Genetically sterile animals
Inventor: FAHRENKRUG SCOTT
IPC: C12N15/02
Filed: 2014-04-29
Abstract: A genetically modified male swine, and methods of making and using the same, the animal comprising a genetic modification to disrupt a DAZL gene selectively involved in gametogenesis, wherein the disruption of the target gene prevents formation of functional spermatozoa of the animal. Animals that create progeny with donor genetics, and methods of making and using the same. Cells, and methods of making and using the cells, with a genetic modification to disrupt a target gene selectively involved in gametogenesis.
Patent NZ-716017-A (NZ)
Title: Composition for the management of nausea and vomiting
Inventor: VRANDERICK MANON
IPC: A61P1/08
Filed: 2014-03-13
Abstract: A pharmaceutical dosage system comprising (a) an effective amount of one or more of (i) Doxylamine and (ii) a pharmaceutically acceptable salt thereof; (b) an effective amount of one or more of (i) a Pyridoxine compound of formula II, in which formula II is represented in the Abstract Drawing, wherein R1 is a hydroxyl or phosphate group; and R2 is CH2OH, CHO, or CH2NH2; (ii) a pharmaceutically acceptable ester of (i); and (iii) a pharmaceutically acceptable salt of any of (i)-(ii); and (c) an effective amount of one or more of riboflavin, riboflavin-5-phosphate, flavin adenine dinucleotide, or a pharmaceutically acceptable salt thereof. The system exhibits an improved pharmacokinetic profile relative to the current Diclectin®/Diclegis® formulation and is useful for example for the alleviation of the symptoms of nausea and vomiting, for example in the case of nausea and vomiting of pregnancy (NVP).
Patent NZ-716472-A (NZ)
Title: Infectious bronchitis vaccines derived from ib-qx-like strains
Inventor: MEINDERS CINDY ALEIDA MARIA
IPC: C12N7/08
Filed: 2009-08-07
Abstract: Disclosed is an isolated attenuated infectious bronchitis (IB) virus deposited with the European Collection of Cell Cultures (ECACC) under provisional accession No. 09061004.
Patent NZ-721374-A (NZ)
Title: Substituted piperidinyl-tetrahydroquinolines and their use as alpha-2c adrenoreceptor antagonists
Inventor: REDLICH GORDEN
IPC: C07D417/14
Filed: 2014-12-16
Abstract: The invention relates to novel substituted piperidinyl-tetrahydroquinolines of formula (I), methods for producing same, their use for treating and/or preventing diseases, and their use in the production of medications for treating and/or preventing diseases, particularly for treating and/or preventing diabetic microangiopathies, diabetic abscesses of the extremities, particularly promoting tissue repair in diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart diseases, peripheral vascular and cardiovascular diseases, thromboembolic diseases and ischaemia, peripheral circulatory disorders, Raynaud’s phenomenon, CREST syndrome, microcirculatory disorders, intermittent claudication, and peripheral and autonomic neuropathies.
Patent NZ-722653-A (NZ)
Title: Fastener driving tool with portable pressurized power source
Inventor: LARGO MARC DAVID
IPC: B25C1/04
Filed: 2012-10-02
Abstract: Disclosed is a fastener driver tool powered by a pressurized power source having a supply of compressed fluid. The tool comprises a tool nose (18), a magazine (22), a cylinder (34), a control system (76), a workpiece contact element (96) and a magnet. The magazine (22) is configured to store a plurality of fasteners and to supply the fasteners to the tool nose (18). The cylinder (34) includes a reciprocating piston associated with a driver blade movable to sequentially engage the fasteners from the magazine (22) as the fasteners are supplied to the tool nose (18). The control system (76) is operable to directly electrically control a flow of the compressed fluid from the pressurized power source to the cylinder (34) to directly drive the piston. The workpiece contact element (96) is reciprocatable relative to the tool nose (18) between a rest position and an actuation position. The magnet is associated with the tool nose (18) in a fixed position and is configured to hold the workpiece contact element (96) at the rest position through magnetic attraction with the workpiece contact element (96) and return the workpiece contact element (96) to the rest position after fastener driving, during which the workpiece contact element (96) reciprocates relative to the tool nose (18) between the rest position and the actuation position.
Patent NZ-729293-A (NZ)
Title: Mono-, di- or polysaccharide used as metal inhibitor in the preparation of 68ga-chelate-functionalized targeting agent
Inventor: WOUTERS LUDOVIC
IPC: A61K51/04
Filed: 2015-07-28
Abstract: The present invention relates the use of metal inhibitor in radiolabelling reactions using radioactive metals.
Patent NZ-742895-A (NZ)
Title: Folded uwb monopole antenna for body mounted transmitter and manufacturing method
Inventor: FARKAS ALEXANDER T
IPC: H01Q9/42
Filed: 2016-11-23
Abstract: Systems and methods improve tracking performance of an ultra-wide-band (UWB) tracking tag positioned on a player on a sporting field. A UWB antenna is formed with power radiated disproportionately in forward and backward directions as compared to sideways. The UWB tracking tag is aligned with the UWB antenna when positioned on the player such that less power is absorbed by the player than radiated away from the player. The UWB antenna is monopole and may be folded from a single metal sheet forming: a flat top; a first side folded at an acute angle from one edge of the top; a second side folded at an acute angle from another edge of the top; a first solder tab folded at an obtuse angle from the first side; and a second solder tab folded at an obtuse angle from the second side, to join in parallel with the first solder tab.
Patent NZ-774859-A (NZ)
Title: Sting agonistic compound
Inventor: KOKUBO MASAYA
IPC: C07D498/04
Filed: 2019-10-10
Abstract: The problem to be solved by the present invention is to provide a drug containing a compound having an agonistic activity to STING as an active ingredient. As a result of intensive studies by the inventors of the present invention, the compound represented by the following general formula (I-1) [in the formula, all symbols represent the same meanings as described in the present specification.] or the like, having an agonistic activity to STING, as a substance capable of solving such problems, was found and this invention was completed. Since the compound represented by the general formula (I-1) or the like of the present invention has an agonistic activity to STING, it can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.
Patent NZ-783543-A (NZ)
Title: Inter-penetrating elastomer network derived from ground tire rubber particles
Inventor: COE WILLIAM
IPC: C08L95/00
Filed: 2018-08-02
Abstract: An asphalt pavement comprising a crystalline aggregate, where the aggregate has a film of interfused asphalt molecules and nano-carbon clusters at energy transfer regions associated with impingement points of the aggregate. The film comprises a polymeric matrix comprising a crosslinked network of end-of-life tire derived rubber and at least one complementary polymer. The matrix is derived from an aqueous slurry of vulcanized rubber particles and copper acetate that has been introduced into an electromechanical reactor which induces delamination of a rubber matrix within the vulcanized rubber particles and disrupting sulfidic linkages between the particles. The matrix encapsulates carbon black and/or graphene particles derived from the tire rubber. The clusters are adapted to shield and/or stabilize the asphalt molecules from energy of polariton discharges generated at the energy transfer regions by rolling load on the paving material.
Patent PT-102866-A (PT)
Title: Motor vehicle ecological and ambient driving simulator enables driver to be aware of energetic and ambient performance such as fuel consumption and emission of pollutants
Inventor: FARIAS TIAGO ALEXANDRE ABRANCH
IPC: G09B9/052
Filed: 2002-11-06
Abstract: The motor vehicle ecological and ambient driving simulator enables a driver to be aware of energetic and ambient performance at the end of a journey, such as fuel consumption and emission of pollutants into the atmosphere. The emission refers to non-burnt hydrocarbons, carbon monoxide, nitrous oxide, particles and carbon dioxide. The simulator is constituted by a steering wheel, brake pedal, accelerator pedal and, optionally, a clutch pedal. All these components are linked to a display screen in the vehicle. Also shown are the road, the surrounding area, and the performance of the vehicle, such as speed gauge, rotation counter, indicator of automatic or manual gearbox selector, indicators of instantaneous fuel consumption and pollutant emission. At the end of each journey, there is a final indication on the screen of average speed, distance covered, average fuel consumption and a quantitative classification of driving.
Patent PT-104212-A (PT)
Title: Central eléctrica oceânica
Inventor: PERES RODRIGO DE SOUSA
IPC: F03B13/14
Filed: 2008-10-13
Abstract: REFERE-SE ESTA INVENÇÃO A UMA CENTRAL ELÉCTRICA OCEÂNICA DESTINADA A PRODUZIR ENERGIA ELÉCTRICA A PARTIR DAS MARÉS, CORRENTES E ONDAS. É CONSTITUÍDA, ESSENCIALMENTE, POR UMA PLATAFORMA BASILAR (PB) DE ONDE SE ERGUE UMA COLUNA CILÍNDRICA (CC) ONDE RODA UM EIXO (E) ENCIMADO POR UM DISPOSITIVO (D) CONSTITUÍDO ESSENCIALMENTE PELAS CÁPSULAS FLUTUANTES (CF) PORTADORAS DE GERADORES (G) LIGADOS UM AO OUTRO POR UM VEIO (V) PROVIDO DE PALHETAS HIDRÁULICAS IMPULSIONADORAS (P). AS REFERIDAS CÁPSULAS SOBEM E DESCEM COM A SUBIDA E DESCIDA DAS ÁGUAS, PASSANDO A CORRENTE PRODUZIDA PARA O CONDUTOR ELÉCTRICO GERAL (CEG), ATRAVÉS DE UMA ESFERA GIRATÓRIA E CONDUTORA (EG) VOLVIDA PELOS CONDUTORES FIXOS (CF3) E (CF4) DO CASQUILHO (C2), AO QUAL SE LIGA O REFERIDO CONDUTOR GERAL. O SISTEMA CONSTANTE DO SEGUNDO PARÁGRAFO DESTE ''RESUMO'' ONDE RODA O DISPOSITIVO (D), PODE, QUANDO NECESSÁRIO OU VANTAJOSO, SER SUBSTITUÍDO POR OUTRO SISTEMA CONSTITUÍDO, ESSENCIALMENTE, POR UMA CAIXA CIRCULAR BOIANTE, PRESA POR CABOS (CAB) AO LEITO OCEÂNICO, CONFORME DESENHO Nº2.