baber/WOPTO huggingface dataset:
Patent DE-69224209-D1 (DE)
Inventor: ROCKENFELLER UWE
IPC: C09K5/04
Filed: 1992-11-24
Granted: 1998-02-26
Abstract: An apparatus comprises a plurality of two or more reaction chambers, each having a different compound therein comprising a solid reactant adsorbent and a gaseous reactant adsorbed thereon, each of said compounds having a different gaseous refrigerant vapor pressure, substantially independent of the concentration of the gaseous reactant, and having an ascending order of gaseous reactant vapor pressure wherein the adsorption temperature of a lower vapor pressure compound at adsorption temperature of a lower vapor pressure compound at adsorption pressure is at least 8 DEG  DEG C. higher than the desorption temperature of the next successive higher vapor pressure compound at desorption pressure, means for directing heat transfer fluid to an from said reaction chambers whereby heat from an exothermic adsorption reaction is directed to a reaction chamber for driving an endothermic desorption reaction, and heat exchange means for selectively recovering and/or adsorbing heat from said reaction chambers, refrigerant condenser means comprising a single condenser or two or more condensers, each operating at a different temperature, and refrigerant evaporator means comprising a single evaporator or two or more evaporators, each operating at a different temperature. Other improvements comprise a vapor recuperator and a liquid subcooler.
Patent DE-69228700-D1 (DE)
Inventor: RUOSLAHTI ERKKI
IPC: A61K38/17
Filed: 1992-12-04
Granted: 1999-04-22
Abstract: The present invention provides a method for treating or arresting the progress of pathologies characterized by an accumulation of extracellular matrix components by providing an agent to suppress the activity of transforming growth factor  beta  (TGF- beta ) a peptide growth factor which is anabolic and leads to fibrosis and angiogenesis. Pathologies which can be so treated include the various fibrotic diseases such as fibrotic cancer, fibrosis of the lungs, arteriosclerosis, post myocardial infarction, cardiac fibrosis, post-angioplasty restenosis, renal interstitial fibrosis, scarring and diabetic nephropathy. The present invention further provides methods for treating diabetes and pharmaceutical compositions useful in such methods.
Patent DE-69229126-D1 (DE)
Inventor: HOLLY RICHARD
IPC: C12N5/10
Filed: 1992-12-30
Granted: 1999-06-10
Abstract: Methods are disclosed for producing thrombin. The protein is produced from host cells transformed or transfected with DNA construct(s) containing information necessary to direct the expression of thrombin precursors. The DNA constructs generally include the following operably linked elements: a transcriptional promoter, DNA sequence encoding a gla-domainless prothrombin, and a transcriptional terminator. Thrombin precursors produced from transformed or transfected host cells are activated either in vivo or in vitro.
Patent DE-69301241-D1 (DE)
Inventor: FRADENBURGH EVAN
IPC: B64C27/28
Filed: 1993-05-26
Granted: 1996-02-15
Abstract: A variable diameter rotor for a tilt rotor aircraft has an inboard section having a linear twist from a root end to an outboard end thereof, and an outboard section telescoped over the inboard section which additionally has a linear twist from a root end to an outboard end thereof. The outboard section is disposed at an offset of about 4 DEG  to 15 DEG  relative to the inboard section to provide a step wise change in twist angle when in the extended condition, such that the rotor when operated in the helicopter mode, can be operated at high blade pitch angles without premature stalling along the inboard airfoil surfaces This allows efficient operation at high thrust coefficient/solidarity ratios. Optionally, the trailing edge of the outboard section is rotated along the aft 30% of chord of the airfoil section to provide an equivalent twist increase in the offset at the transition between the blade sections. When in the forward flight cruise mode, the inboard equivalent twist increment allows operation of the inboard airfoil sections at higher pitch angles to reduce negative lift regions and increase cruise propulsion efficiency.
Patent DE-69310931-D1 (DE)
Inventor: BALANTINE DOUGLAS ASHLEY
IPC: A23F3/18
Filed: 1993-12-16
Granted: 1997-06-26
Abstract: Clear consumer acceptable acidified ready-to-drink tea products prepared from instant teas as well as fresh brewed teas and methods for their preparation are disclosed. A tea solution containing 0.3 % tea solids or less is stabilised, before of after acidifying to a pH of 4,5 or less, by the addition of gum arabic in an amount of 50 to 500 ppm.
Patent DE-69315065-D1 (DE)
Inventor: MOSSUZ GABRIEL
IPC: G04B19/24
Filed: 1993-06-16
Granted: 1997-12-11
Abstract: Timepiece with a date indicator (1) with internal toothing moving angularly one notch each day, at least one rotary indicating means (12) driven by the said date indicator and intended to indicate cyclic parameters such as the date, the lunar phase, the "cash balance", etc. Several types of indication, all controlled by the date indicator, make it possible to produce a panoply of watches, of simple construction, with various display combinations. <IMAGE>
Patent DE-69316236-D1 (DE)
Inventor: MORRISSEY MICHAEL
IPC: A61P11/00
Filed: 1993-11-12
Granted: 1998-02-12
Abstract: PCT No. PCT/US93/10876 Sec. 371 Date Jul. 25, 1995 Sec. 102(e) Date Jul. 25, 1995 PCT Filed Nov. 12, 1993 PCT Pub. No. WO94/11341 PCT Pub. Date May 26, 1994   <IMAGE>  (I)  The invention relates to the compounds of formula (I) wherein the C(=NH)-NHR3 group may be in tautomeric or isomeric form, and pharmaceutically acceptable salts thereof, in which: R1 is amino which is mono- or disubstituted by a substituent selected from an aliphatic hydrocarbon radical, an araliphatic hydrocarbon radical, an aromatic radical, and a cycloaliphatic hydrocarbon radical or is amino which is disubstituted by a divalent aliphatic hydrocarbon radical or a said radical interrupted by oxygen; R2 is hydroxy which is etherified by an aliphatic alcohol which is substituted by carboxy, by esterified carboxy or by amidated carboxy; R3 is hydrogen or an acyl radical which is derived from an organic carbonic acid, an organic carboxylic acid, a sulfonic acid, or a carbamic acid; X1 and X3, independently of one another, are oxygen (-O-) or sulphur (-S-); and X2 is a divalent aliphatic hydrocarbon radical which may be interrupted by an aromatic radical. The compounds are useful as selective LTB4 receptor antagonists in the treatment of conditions or syndromes in mammals which are responsive to LTB4 receptor antagonism.
Patent DE-69318512-D1 (DE)
Inventor: CORNILS GERD
IPC: B29C48/155
Filed: 1993-09-29
Granted: 1998-06-18
Abstract: Process for producing an automobile pane, equipped with a frame of elastomer of a predetermined shape by extruding the elastomer onto the periphery of the pane and beyond the pane and defining at least a part of the shape of the elastomer as it is extruded by positioning mold surfaces beyond the periphery of the pane.
Patent DE-69323754-D1 (DE)
Inventor: DOLLING ULF H
IPC: C07J73/00
Filed: 1993-11-12
Granted: 1999-04-08
Abstract: Disclosed is a new process for producing finasteride which involves reacting the magnesium halide salt of 17β-carboalkoxy-4-aza-5α-androst-1-en-3-one with t-butylamino magnesium halide, present in at least a 2:1 molar ratio to the ester, formed from t-butyl amine and an aliphatic/aryl magnesium halide at ambient temperature in an inert organic solvent under an inert atmosphere followed by heating and recovering the product finasteride.Also disclosed are two polymorphic crystalline Forms I and II of finasteride, and methods of their production.
Patent DE-69327293-D1 (DE)
Inventor: BARNETT CHARLES JACKSON
IPC: C07D471/04
Filed: 1993-10-13
Granted: 2000-01-20
Abstract: This invention relates to intermediates, and processes thereto, for the preparation of tetrahydropyrido[2,3-d]pyrimidines which are useful for the treatment of susceptable neoplasms.
Patent DE-69328996-D1 (DE)
Inventor: CHABRAND CHRISTINE JACQULINE
IPC: C08F4/60
Filed: 1993-08-23
Granted: 2000-08-17
Abstract: Novel metallocene complexes are disclosed comprising polmerisable olefinic groups for example vinyl. The complexes may be combined with activators such as methyl aluminoxane for the polymerisation of olefins.
Patent DE-69333036-D1 (DE)
Inventor: JACOBS ERIC
IPC: C07K16/12
Filed: 1993-06-15
Granted: 2003-07-17
Abstract: The subject of the present invention is a DNA fragment encoding a protein capable of being recognised by an antiserum to the transferrin receptor the N. meningitidis strain IM2394 or IM2169 as well as a process for producing the said protein by the recombinant route. As examples, such a DNA fragment encodes the subunit tbp1 of the strain IM2394 or IM2169 or the subunit tbp2 of the strain IM2394 or IM2169.
Patent DE-69333812-D1 (DE)
Inventor: KAZUHIKO NISHITANI
IPC: C12N15/09
Filed: 1993-03-24
Granted: 2005-06-23
Abstract: The enzyme endo-xyloglucan transferase is provided, together with a gene coding for the enzyme, antisense DNA of the gene and antisense RNA of the gene. The gene may be cloned and the enzyme may be produced using the gene. The expression of the enzyme in a living organism may be controlled and the morphology of a plant may be regulated. The enzyme may be used to transfer xyloglucan molecules.
Patent DE-69400154-D1 (DE)
Inventor: JUBB GARY ANTHONY
IPC: C04B35/22
Filed: 1994-01-12
Granted: 1996-05-23
Abstract: Saline soluble inorganic refractory fibre comprising at least 21.8 mol.% SiO2, CaO, MgO, opt. ZrO2, opt. less than 0.75 mol.% Al2O3, and less than 2 mol.% of incidental impurities, where if the amt. of CaO exceeds the sum of the amt. of MgO and twice the amt of ZrO2, the ratio of diopside to wollastonite does not lie in the range of 1.8-5.25. A vacuum cast preform of the refractory fibre has a shrinkage of 3.5 % or less when exposed to 1260 deg. C for 24 hrs. The refractory fibre pref. contains less than 0.5 mol.% Al2O3, and where the amt. of CaO is less than the sum of the amt. of MgO and twice the amt. of ZrO2. The amt. of MgO is pref. greater than the amt. of CaO, and the amt. of MgO minus the sum of the amt. of ZrO2 + Al2O3 exceeds 10 mol.%, pref. exceeds 11.3 mol.% and esp. exceeds 15.25 mol.%. The incidental impurities include less than 1.25 mol.%, pref. less than 0.8 mol.% of TiO2, less than 1.0 wt.%, pref. less than 0.3 wt.% of Na2O and less than 1.0 wt.%, pref. less than 0.6 wt.% of Fe2O3.
Patent DE-69403642-D1 (DE)
Inventor: COOK PHILLIP
IPC: A61P35/00
Filed: 1994-03-21
Granted: 1997-07-10
Abstract: Oligonucleotides, which incorporate 7-deazanucleosides, are useful as antisense sequences to inhibit the function of RNA and DNA.
Patent DE-69418249-D1 (DE)
Inventor: WIEDEMANN WOLFGANG ULRICH
IPC: A61C17/22
Filed: 1994-05-25
Granted: 1999-06-10
Abstract: A tooth-brush is provided which has a brush shank (4) adapted to be driven electrically by a drive (2) and provided with a brush-head (5) having bristles (6), which brush-head performs movement (8), for example, a loosening movement whose frequency is higher than 30 Hz and whose amplitude is between 0.1 mm and 5 mm, which brush-head performs an additional movement (9), for example, a wiping movement having a frequency of between 1 Hz and 5 Hz. The combination of a rapid loosening movement and a slow wiping movement ensures that the teeth are cleaned in a thorough but gentle manner.
Patent DE-69419000-D1 (DE)
Inventor: MOSES CHARLES J
IPC: E21B17/01
Filed: 1994-09-07
Granted: 1999-07-15
Abstract: A continuous bend flexible/rigid riser system is provided for coupling a subsea location to an offshore platform or vessel. The riser system comprises a first rigid pipe section coupled at its upper end to the platform. A plurality of intermediate pipe sections are mutually coupled end to end, and are coupled in series with the first rigid pipe section by means of a plurality of flexible couplings. The lower end of the last in the series of intermediate pipe sections is coupled to the subsea location. The flexible/rigid riser system reduces bending stresses transmitted along the riser by allowing angular displacement of the pipe sections with respect to one another.
Patent DE-69432255-D1 (DE)
Inventor: BECKNER E
IPC: C07K16/00
Filed: 1994-06-23
Granted: 2003-04-17
Abstract: The present invention relates, in general, to AAMP-1, and to a peptide derived from the amino-terminal region of AAMP, P189. In particular, the present invention relates to a DNA segment encoding AAMP-1, P189 or fragments thereof; polypeptides encoded by said DNA segment; recombinant DNA molecules containing the DNA segment; cells containing the recombinant DNA molecule; a method of producing a AAMP-1, and P189 polypeptide or fragments thereof; antibodies specific to AAMP-1; and a method of measuring the amount of AAMP-1 in a sample. The present invention further relates to methods of using AAMP, P189 or fragments thereof in promoting cell-cell or cell-substrate adhesion, wound healing in patients, prosthetic acceptance, concentrating heparin in tissues, and inhibiting metastases and invasion of malignant cells.
Patent DE-69501329-D1 (DE)
Inventor: GUILLIN FRANCOIS
IPC: B65D43/02
Filed: 1995-07-03
Granted: 1998-02-05
Abstract: The food packaging box comprises a bottom (F) having a lateral peripheral wall (10) which is widened along an edge (2) external to the wall surface. The edge has a groove (3) forming a protuberance in the edge plane. A cover (C) comprising a bowl clips onto the groove in the bottom to enclose the contents. A transverse incision (4) in the groove passes through all the width of the groove which is extended under the cover in peripherally folded bulges. These ensure hermetic sealing and evidence of non tampering. There is an interruption (5) in the edge upper bulge and parallel vertical ribs (5) acting as rigidifying beams. Vertical sealing is effected by the external lateral surface of the cover and the internal lateral surface of the bottom upper portion. These two surfaces are in friction contact along the largest part of their height. Placing the cover on the box simultaneously engages the vertical sealing and the horizontal security.
Patent DE-69502923-D1 (DE)
Inventor: ARMSTRONG JEFFREY L
IPC: B62J17/04
Filed: 1995-11-29
Granted: 1998-07-16
Abstract: A detachable motorcycle windshield assembly (11) includes a windshield (12), a pair of mounting brackets (27, 28) attached respectively to each side of the windshield (12) and each including an upper portion (3) and a lower portion (34) extending downwardly from the upper portion. A first socket (42) is formed on the lower portion (34) of each bracket (27, 28) for pivotally engaging a first bushing (60) fixed to the motorcycle and a second socket (44) is formed on the upper portion (30) of each bracket (27, 28) for engaging a second bushing (62) fixed to the motorcycle generally above the first bushing (60). Each bracket (27, 28) is also fitted with a latch (48) for releasably securing the second socket (44) to the second bushing (62). <IMAGE>
Patent DE-69507210-D1 (DE)
Inventor: ALBRECHT THOMAS ROBERT
IPC: G11B5/584
Filed: 1995-06-16
Granted: 1999-02-25
Abstract: A track following servo system is disclosed for use with magnetic recording media 20 in which magnetic servo track 27 patterns contain transitions recorded at more than one azimuthal orientation across the width of the servo track. The timing of a signal derived from reading at any point across the width of such a pattern varies continuously as the read head is moved across the servo track. The pattern is read by a servo read head 26 whose width is small compared to the servo track pattern. The combination of a wide servo pattern and a narrow servo read head offers excellent position sensing linearity and dynamic range. In the preferred embodiment, the servo read head is also narrow with respect to the data tracks, which provides the additional advantages of superior immunity to position sensing errors caused by defects or temporal variations in the servo read head, defects in the servo pattern, wear of the head, or debris collection. Position sensing with this system is achieved by deriving a ratio of two servo pattern intervals and therefore is insensitive to medium speed during reading. The servo patterns may include spacing intervals 70 recognizable for error detection and correction purposes. The servo tracks may be recorded using a patterned multiple gap servo write head 400 whose magnetic gaps have geometries appropriate to generate the desired servo patterns. <MATH>
Patent DE-69513979-D1 (DE)
Inventor: SHELLEY NICHOLAS
IPC: A61L24/06
Filed: 1995-06-19
Granted: 2000-01-20
Abstract: PCT No. PCT/GB95/01423 Sec. 371 Date Dec. 31, 1996 Sec. 102(e) Date Dec. 31, 1996 PCT Filed Jun. 19, 1995 PCT Pub. No. WO96/01089 PCT Pub. Date Jan. 18, 1996The invention provides a drainage bag, such as an ostomy bag or like drainage bag, for receiving bodily waste, the drainage bag having a wall portion (1) formed of a water-softenable or hot-water-soluble first film material, the wall portion (1) having an opening (4) therein for receiving the bodily waste or bodily fluid; a water-impermeable, water-insoluble polymeric film material (7) being adhered to the outer surface of the said wall portion (1) so as to surround said opening, the water-impermeable, water-insoluble layer (7) being adhered to the said wall portion by means of a cyanoacrylate layer (6) interposed therebetween; and the outer surface of the water-impermeable, water-insoluble layer (7) having secured thereto an adhesive flange (5) for securing the drainage bag to the body wall of a patient.
Patent DE-69517028-D1 (DE)
Inventor: TUCCELLI RONALD
IPC: B01D71/10
Filed: 1995-07-19
Granted: 2000-06-21
Abstract: A cellulosic ultrafiltration membrane is provided having a microporous base resistant substrate and an ultrafiltration layer form of a cellulose ester or cellulose.
Patent DE-69532244-D1 (DE)
Inventor: VOSS I
IPC: A61M5/00
Filed: 1995-09-11
Granted: 2004-01-15
Abstract: Impedance to fluid flow in a fluid delivery line is measured. Two techniques are used depending on the flow rate selected. For high flow rates, the pump is controlled to vary the flow rate and the change in pressure is divided by the change in flow to directly determine the resistance. For low flow rates, a processor controls the pump to pump flow quantities in accordance with a pseudo-random binary code. The resulting pressure signal sensed at the conduit is decoded in accordance with that code. Pressures received during code periods of no flow are subtracted from pressures received during code periods of flow. Pressure offset is also removed and a least squares estimation approach is used with a linear prediction model to determine impedance. The coefficients determined in the model are used to calculate the resistance to fluid flow of the system. A quality supervisor monitors the resistance determination process and controls the display of resistance depending on the quality determined. A resistance display continuously displays the resistance of the system.
Patent DE-69535592-D1 (DE)
Inventor: FOSTER ROBERT R
IPC: C07D211/90
Filed: 1995-03-27
Granted: 2007-10-25
Abstract: A method of enhancing the efficiency and increasing the duration of action of drugs (e.g. dihydropyridines and anti-bacterials) and particularly of nifedipine and penicillins wherein one or more hydrogen atoms are deuterated and wherein the deuterated drug has unexpectedly improved properties when used in much lower concentrations than unmodified drug. A method for determining the identity and bioequivalency of a new drug is also disclosed wherein the molecular and isotope structure of a new drug is determined by isotope ratio mass spectrometry and compared with the molecular and isotope structure of a known human drug.
Patent DE-69602951-D1 (DE)
Inventor: GODARD BRUNO
IPC: B23K26/06
Filed: 1996-08-06
Granted: 1999-07-22
Abstract: PCT No. PCT/FR96/01251 Sec. 371 Date Jan. 21, 1998 Sec. 102(e) Date Jan. 21, 1998 PCT Filed Aug. 6, 1996 PCT Pub. No. WO97/07423 PCT Pub. Date Feb. 27, 1997An optical device for homogenizing a laser beam is described. Such a device is commonly used in the surface treatment of an object. The device consists of front lenses that are bonded together to form an assembly of lenses that breaks the laser light into multiple beams. This results in the homogenization of the gaussian profile of the beam intensity as viewed perpendicular to the beam's propagation. Advantageously the matrix of lenses is formed using groves or bevels in a manner that minimizes losses resulting from light impinging on glue disposed upon the entire lateral surface of the front lenses. In the invention gaps between front lenses that cause interference with the light path are eliminated. This gap free bonding is accomplished by filling the groves or bevels with glue, inserting a rod or wire into the grove to assemble the front lenses in a support frame, bonding a grill to assembled front lenses, or by using a combination of gluing with a support frame.
Patent DE-69605367-D1 (DE)
Inventor: MANTOVAN GIANFRANCO
IPC: C21D9/00
Filed: 1996-07-23
Granted: 2000-01-05
Abstract: A facility for in-line heat treatment of hot-rolled products, for example, long rods (16) comprises, in combination: a tank (11) suitable for containing a refrigerating liquid medium (12), a plate (13) with stationary rakes (14) and mobile rakes (15) suitable for receiving the products (16) and transporting them through the tank (11) and outside of it on heat treatment performed, and closure lids (27) arranged above said plate (13). <IMAGE>
Patent DE-69607470-D1 (DE)
Inventor: TIPLER KEITH CHARLES
IPC: B65D81/24
Filed: 1996-08-02
Granted: 2000-05-04
Abstract: PCT No. PCT/GB96/01887 Sec. 371 Date Nov. 6, 1998 Sec. 102(e) Date Nov. 6, 1998 PCT Filed Aug. 2, 1996 PCT Pub. No. WO97/06074 PCT Pub. Date Feb. 20, 1997A foodstuff preserving packaging comprising a packaging substrate having a layer of a bonding agent including at least one foodstuff preservative.
Patent DE-69611346-D1 (DE)
Inventor: FARE ROSALDO
IPC: D01D5/34
Filed: 1996-05-29
Granted: 2001-02-01
Abstract: In a method and apparatus for making two-component fibers, a polymer (B) which is supplied laterally with respect to a further polymer (A) and a die (12), is at first distributed inside cross-channels (23) provided in a pre-die (14), and then being redirected, through holes (16), in the extruding direction. The channels (23) operate to rearrange the polymeric mass with the new distribution above the die, so as to eliminate possible discontinuities of the values of the chemical-physical parameters of this mass and which are due to the direction variation the mass is subjected to as it is switched from the side channels (20, 22) to the cross channels (23). Thus, a constant value of the mentioned parameters through the polymer mass being supplied to the extruder is assured. <IMAGE>
Patent DE-69618628-D1 (DE)
Inventor: HOLLOMAN C
IPC: A01N61/00
Filed: 1996-05-31
Granted: 2002-02-21
Abstract: A process for preparing defined molecular weight polymers, particularly polyquaternary ammonium compounds, is disclosed. As the molecular weights of these compounds can be absolutely defined, rather than defined merely in terms of "number average molecular weight," these compounds are particularly useful as identification standards for other polymers which are made using conventional polymerization processes. The polyquaternary ammonium compounds described are further suitable for use as antimicrobial agents, particularly in ophthalmic compositions.