baber/WOPTO huggingface dataset:
Patent EP-0928200-B1 (EP)
Inventor: CHAMBON PIERRE
IPC: A61P17/02
Filed: 1997-08-28
Granted: 2003-04-09
Abstract: The present invention provides compositions and methods for treating an animal, preferably a human, suffering from or predisposed to a physical disorder by administering an effective amount of a composition comprising at least one RAR antagonist, preferably an RARalpha antagonist, and at least one RXR agonist. The combination of an RXR agonist, which has no therapeutic effects alone, with an RAR antagonist allows the use of lower doses of the RAR antagonist than were previously thought to be efficacious; this approach obviates many of the undesirable physiological side-effects of treatment with RAR antagonists.
Patent EP-0952976-B1 (EP)
Inventor: WHITNEY MICHAEL A
IPC: C12Q1/68
Filed: 1997-09-26
Granted: 2002-12-11
Abstract: The invention provides methods for determining a cellular response profile for a target or chemical, for screening compounds for activity as an activator or inhibitor of a target and for developing a cell sensor panel. Furthermore, cell sensor panels are provided. Generally, the methods comprise inserting a BL (beta-lactamase) expression construct via a viral vector into an non-yeast eukaryotic genome, contained in at least one living cell, contacting the cell with a predetermined concentration of a modulator, and detecting BL activity in the cell.
Patent EP-0872438-B1 (EP)
Inventor: KLEINEISEL GEORG
IPC: B65H3/08
Filed: 1998-03-26
Granted: 2002-07-10
Abstract: The device has a fixed support structure (7) with an outer and inner pair of cross slides (8a,8b;9a,9b) with the two vertical slides (17) of each pair spaced from each other transversely. The transverse spacing (a) between the vertical slides of the outer pair is greater than the transverse distance (b) between the vertical slides of the inner pair. The two vertical slides of each pair are connected together by a cross bar (21,22) which together with at least one holder element (25) mounted on same forms a holding device for a metal plate (2). The two vertical slides of the outer pair and the associated cross bar form a U-shaped outer support frame (23) when seen in the longitudinal direction. The two vertical alides of the inner pair and the associated cross bar form a U-shaped inner support frame (24).
Patent EP-0913652-B1 (EP)
Inventor: HIEBINGER ALFONS
IPC: F25C1/16
Filed: 1998-10-28
Granted: 2004-11-03
Abstract: The product is placed in a vacuum chamber in which the pressure is reduced by a vacuum pump until water vapor leaves the product. It is then cooled by direct evaporation cooling and absorbed in a zeolite bed before the vacuum pump. Evacuation of the vacuum chamber is matched to the absorption characteristics of the zeolite bed so that the product achieves the desired state e.g. temperature, water content etc. No water vapor flows through the zeolite to the vacuum pump.
Patent EP-0870625-B1 (EP)
Inventor: COVE MICHAEL GERALD
IPC: B41M5/333
Filed: 1998-03-24
Granted: 2001-10-10
Abstract: Thermally responsive record material comprises a support having provided thereon in substantially contiguous relationship in one or more layers an electron donating dye precursor, an acidic developer material, a sensitizer, and a binder therefor. The sensitizer comprises at least two components, the first component comprising 2,2-bis(4-hydroxyphenyl)-4-methylpentane and the second component comprising a mixture of dimethyl terephthalate and 1,2-diphenoxyethane. The first component is preferably in a weight ratio of from 1:2 to 2:1, more preferably 1:1, relative to the second component. The second component comprises from 50 to 70%. dimethyl terephthalate. The sensitizer is prepared by admixing the first component and the second component and grinding the sensitizer to a particle size of less than 1 micron.
Patent EP-0936141-B1 (EP)
Inventor: SUOLAHTI YRJOE
IPC: B65B11/02
Filed: 1998-11-20
Granted: 2001-09-19
Abstract: Wrapping apparatus for winding a wrapping foil web (F) around an object (1) to be packaged, said wrapping apparatus comprising a foil dispenser (2) arranged to circulate along a ring-like endless track (3) around the object to be packaged, which foil dispenser (2) comprises a frame (4), a detachable and replaceable foil roll (5) mounted on the frame, supporting elements (6) for supporting the foil roll on the frame, and tensioning means (7) for braking foil delivery from the roll and maintaining a predetermined foil tension. The tensioning means (7) comprise a sensor (8) for detecting foil web tension, and an electric motor (9) for driving the foil roll (5), the torque, speed of rotation and/or direction of rotation of said electric motor being controlled on the basis of foil tension as detected by the sensor. <IMAGE>
Patent EP-0857498-B1 (EP)
Inventor: THOMKE ROLAND
IPC: A63C5/03
Filed: 1998-02-02
Granted: 2001-08-22
Abstract: The binding system for sports equipment, and especially snowboards, has a central screw (24) at an angle to the base plane of a mounting socket (4). It is at right angles to its upper side and with its axis (9) on the rotary axis for the rotation of the carrier (7) for the binding section. The central screw is keyed to the binding carrier, at the rotating setting unit (6) on the mounting socket, to pass through at right angles to its under side.
Patent EP-0965122-B1 (EP)
Inventor: AVIAN OSCAR
IPC: G10K11/172
Filed: 1998-02-26
Granted: 2002-11-27
Abstract: Method to produce sound-proofing panels or surfaces for interiors, used to line walls or ceilings or as partition elements for interiors such as study rooms, meeting rooms, work rooms, etc., the panels or surfaces including inside lengthwise through holes (11) extending for the entire length of the panel and separated transversely and defining cavities of the desired volume, at least some of the lengthwise through holes (11) communicating with the face of the panel facing towards the room (15) wherein the noise is generated by means of lengthwise slits (12) extending for at least a substantial part of the length of the panel, the sound-proofing panel or surface being obtained by coupling together several finished base elements (110, 310), which include semi-concavities (111, 211) on the respective coupling faces, the semi-concavities (111, 211) of one finished base element (110, 310) being coupled with the semi-concavities (111, 221) of the other finished base element so as to define the lengthwise through holes (11).
Patent EP-0960268-B1 (EP)
Inventor: FISCHER CHRISTIAN
IPC: F02B31/06
Filed: 1998-01-29
Granted: 2002-09-11
Abstract: Ce dispositif pour influencer le courant d'air d'aspiration dans un moteur à combustion interne comprend une pièce mécanique (5) qui peut être insérée dans le courant d'air d'aspiration et qui est montée rotative autour d'un point de rotation (6). Dans une position extrême, cette partie mécanique (5) peut plonger dans le canal d'aspiration (2, 4) et faire tourbillonner l'air aspiré. Le point de rotation (6) de la pièce mécanique en forme de languette rotative (5) se situe à l'extérieur du bloc-cylindres (1) du moteur à combustion interne, dans une tubulure d'aspiration (4).
Patent EP-0973806-B1 (EP)
Inventor: PETTIT DEAN K
IPC: A61K47/48
Filed: 1998-03-05
Granted: 2004-09-22
Abstract: Processes for conjugating proteins with polyethylene glycol are disclosed. The disclosed processes provide modified proteins having little or no decrease in their activity and include the steps of protecting one or more sites on the protein, contacting the protected protein with polyethylene glycol under conditions suitable for conjugating the polyethylene glycol to the protein, and deprotecting the protein. This advantageous retention of a desired protein activity is attributed to the availability of one or more protein binding sites which is unaltered in the conjugation process and thus remains sterically free to interact with a binding partner ligand or cognate subsequent to the conjugation process.
Patent EP-0932899-B1 (EP)
Inventor: BRAAT JOSEPHUS JOHANNES MARIA
IPC: G11B7/135
Filed: 1998-05-07
Granted: 2003-08-20
Abstract: Cette invention se rapporte à un dispositif permettant la lecture optique d'un support d'enregistrement au moyen d'un faisceau rayonnant ayant une ouverture numérique élevée. A cet effet, le faisceau rayonnant est focalisé sur le support d'enregistrement au moyen d'une lentille objectif et d'une lentille plan-convexe. La lentille plan-convexe est distante du support d'enregistrement de plusieurs dizaines de micromètres. Elle focalise le faisceau rayonnant en un point distant d'au moins 30 profondeur focale d'un point aplanétique de la lentille plan-convexe. Ainsi, ladite lentille présente une tolérance relativement grande pour les mouvements latéraux.
Patent EP-0998381-B1 (EP)
Inventor: ASRAR JAWED
IPC: B29C48/05
Filed: 1998-07-24
Granted: 2003-11-19
Abstract: Methods of making PHA coating compositions having molecular weights greater than about 125,000 are provided. The PHA coating compositions derived therefrom have improved properties suitable for applications in which excellent heat sealability and moisture resistance is desired.
Patent EP-1012286-B1 (EP)
Inventor: SERLUPI-CRESCENZI OTTAVIANO
IPC: C07K14/435
Filed: 1998-09-15
Granted: 2006-10-25
Abstract: A predominant allelic variant of the human STAT3 protein, the cDNA sequence encoding it, its use in therapy and/or in diagnosis of autoimmune and/or inflammatory diseases, as well as pharmaceutical compositions comprising it.
Patent EP-1063328-B1 (EP)
Inventor: TAKEUCHI HISAHARU
IPC: A41D27/02
Filed: 1998-12-17
Granted: 2007-03-21
Abstract: A lining cloth of a woven fabric in which the warp yarn comprises either of polyester filamentary yarn or cellulosic filamentary yarn and the filling yarn comprises either a false-twisted polyester filamentary yarn, a raw filamentary yarn or a cellulosic filamentary yarn, characterized in that an elongation in the filling-wise direction of the woven fabric is in a range from 5% to 12%, a coefficient of dynamic friction on the surface of the woven fabric is in a range from 0.20 to 0.45, and a filling-wise crimp index value of the woven fabric as defined by the following formula (1) is in a range from 0.003 to 0.013:  <MATH>   The lining cloth according to the present invention is soft in touch, excellent in slipperiness, resistant to seam slippage and free from wearing pressure. The lining cloth is suitably used as a lining for a skirt which is otherwise liable to ride up.  The lining cloth according to the present invention is produced by heat-treating a grey fabric woven from warp yarns of polyester filament or cellulosic filament and filling yarns of raw polyester filament at a temperature in a range from 160  DEG C to 210  DEG C prior to or after the scouring while being narrowed in width by 5 to 30% relative to the grey fabric.
Patent EP-1045951-B1 (EP)
Inventor: STONE JEFFREY W
IPC: E05D7/10
Filed: 1998-12-29
Granted: 2003-11-19
Abstract: An overhead door includes a plurality of panels pivotally connected to one another with the mating upper and lower edges of the adjacent panels providing a pinch-resistant configuration during articulation of the overhead door. Additionally, the installation and assembly of the door is more easily and efficiently accomplished because of first and second contact locations between the mating upper and lower edges of the panels and the configuration of those contact locations provides registration or alignment of the panels relative to one another during installation. Additionally, the hinge assembly includes a pivot axis which is positioned between the front and back faces of the panel to enhance the pinch-resistant operation of the door and the installation of the hinge is easily accomplished with a reduced number of parts because of cooperating keyhole slots and key on the pivot pin of the hinge.
Patent EP-1044325-B1 (EP)
Inventor: ALBERT WERNER
IPC: F02M35/10
Filed: 1998-12-22
Granted: 2002-03-27
Abstract: L'invention concerne une installation d'aspiration pour une alimentation en air comburant d'un moteur à combustion interne, en particulier pour un véhicule automobile. L'installation d'aspiration selon l'invention comporte un entonnoir d'aspiration (16) présentant un manchon d'aspiration (12) à une extrémité ouverte, ainsi qu'un collecteur d'air (18) sur lequel sont disposés des bras de tuyau d'aspiration (14) pour chaque cylindre pouvant être reliés à une tête de cylindre du moteur à combustion interne. L'entonnoir d'aspiration (16) et le collecteur d'air (18) sont réalisés dans un carter commun (10), une paroi de séparation (22) du carter (10) séparant l'entonnoir d'aspiration (16) du collecteur d'air (18).
Patent EP-0976318-B1 (EP)
Inventor: DENI FRANZ
IPC: A01D78/10
Filed: 1999-07-07
Granted: 2004-10-06
Abstract: The axle (21) of the gyroscopic rake (6) is supported on the ground by at least one runner-wheel. The mechanism (7) driving the gyroscopic rake has horizontal and vertical walls (14-16) which divide the mechanism into a lower part (19) containing elements (24,25) for energy transmission and incorporating bearings (26-28) and sealing elements (29-31). An upper part (18) of the mechanism forming the housing for the energy-transmitting elements in the form of shafts (22) run outside the mechanism in profiled side frames. The horizontal and vertical walls and at least one sealing element define the upper and lower parts so that they are oil-tight.
Patent EP-0989683-B1 (EP)
Title: Mobile phone with SIM card reader
Inventor: BLAECKER BERNHARD
IPC: H04B1/3816
Filed: 1999-09-15
Granted: 2006-06-28
Abstract: The mobile telephone has a control unit, a SIM plug position (14,14') for a SIM card (15), and SIM contacts (17) associated with the SIM plug position. There are also system connectors, including the SIM plug position contacts, for connecting the control unit to an external data processing system, especially for programming, test and maintenance purposes.
Patent EP-0985425-B1 (EP)
Inventor: GUALA GIANNI
IPC: A61M39/28
Filed: 1999-08-26
Granted: 2003-10-22
Abstract: Roller clamp (1) for regulating a fluid flow through an elastically deformable tubing (T), comprising a generally channel-shaped body (2) and a roller (3) longitudinally movable in a guided fashion parallelly to a clamping surface (6) of the bottom wall (4) of the body (2) so as to clamp the elastically deformable tubing (T). Longitudinal lateral recesses (17) are formed between the clamping surface (6) and the lateral walls (5) of the body (2), at least along part of a longitudinal central groove (7) having a decreasing section of the bottom wall (4), which are designed to accommodate elastic expansion of the tubing (T) being clamped. <IMAGE>
Patent EP-1064252-B1 (EP)
Inventor: GENET ALAIN
IPC: C07C271/28
Filed: 1999-03-15
Granted: 2005-06-15
Abstract: The invention concerns an oxidation dyeing composition for keratinous fibers containing at least a monobenzene coupling agent including at least a cationic group Z bearing at least a cyclized or non-cyclized quaternary ammonium unit, the use of said coupling agents for dyeing keratinous fibers, dyeing methods using same, and novel monobenzene coupling agents comprising at least a cationic group Z bearing at least a cyclized or non-cylized quaternary ammonium.
Patent EP-0987995-B1 (EP)
Inventor: BILLET GILLES
IPC: A61C13/01
Filed: 1999-03-23
Granted: 2006-11-29
Abstract: A frame for a removable dental prosthesis has a base part having a layer of woven fabrics of a composite material, which is arranged as a support shell in the form of an arch designed to cover at least a part of the patient's jaw. An intermediate part extends along the top of the base part to form a beam having a good crushing strength, and forming the limits of the section of the frame. A surface part forms a cap totally covering the base part and intermediate part, the material of the cap being formed by a laminated fiber reinforcement material having an organic matrix of the same nature as that of the base part. The assembly, made up of the base part, the intermediate part and the surface part form, after shaping and polymerization, a self-supporting profiled part having a good breaking resistance.
Patent EP-1075717-B1 (EP)
Inventor: BOTEZ DAN
IPC: H01S5/12
Filed: 1999-03-31
Granted: 2003-06-18
Abstract: High power edge emitting semiconductor lasers are formed to emit with very narrow spectral width at precisely selected wavelengths. An epitaxial structure is grown on a semiconductor substrate, e.g., GaAs, and includes an active region at which light emission occurs, upper and lower confinement layers and upper and lower cladding layers. A distributed feedback grating is formed in an aluminum free section of the upper confinement layer to act upon the light generated in the active region to produce lasing action and emission of light from an edge face of the semiconductor laser. Such devices are well suited to being formed to provide a wide stripe, e.g., in the range of 50 to 100 mum or more, and high power, in the 1 watt range, at wavelengths including visible wavelengths.
Patent EP-1094970-B1 (EP)
Inventor: LINDENBERGER WERNER
IPC: B65B61/18
Filed: 1999-07-02
Granted: 2002-09-25
Abstract: To cut the hole in each pouch, the sheet material is shaped near the fold line, between two molding sections (15, 16). It is clamped in this position. A knife is advanced into one section (15), to meet a counter blade on the other (16). Preferred features: The shaping sections are curved about an axis perpendicular to the connection plane of the strips bordering the pouch. The blade (20) section carries a centering peg (21); the opposite section includes a matching guide bore (27). In the fold line of the band sections, an incision is stamped, forming a hole for passage of the (smaller) centering peg. At least one shaping section is heated. The hole center cut-out, is sucked away through a bore (28).
Patent EP-1086207-B1 (EP)
Inventor: PALESE PETER
IPC: A61K39/12
Filed: 1999-06-11
Granted: 2007-01-17
Abstract: The present invention relates, in general, to attenuated negative-strand RNA viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. The invention also relates to the development and use of IFN-deficient systems for selection of such attenuated viruses. In particular, the invention relates to attenuated influenza viruses having modifications to the NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. The mutant viruses replicate in vivo but demonstrate reduced pathogenicity, and therefore are well suited for live virus vaccines, and pharmaceutical formulations.
Patent EP-1086549-B1 (EP)
Inventor: VAN DER WAL JACOBUS CORNELIS
IPC: H04L29/06
Filed: 1999-06-07
Granted: 2006-01-25
Abstract: System for charging the use of a packet based telecommunication network. A measuring device (2) measures the number (n) of data units during a period of time (T) or the period of time (t) between a certain number (N) of data units. At any rate, the period of time is short in relation to the total connection time. A calculation device (4) calculates per period of time the number of data units per unit of time and transmits that calculation result (r) to a billing system (5). If the telecommunication system comprises system data units which comprise an indication (r1) of the capacity or priority requested by the user, that indication can also be passed on to the billings system, as well as an indication of the capacity or priority assigned by the telecommunication system.
Patent EP-1107964-B1 (EP)
Inventor: ALTMANN KARL-HEINZ
IPC: C07D405/14
Filed: 1999-08-09
Granted: 2010-03-03
Abstract: The invention relates to compounds of formula Iwhereinr is from 0 to 2; n is from 0 to 2; m is from 0 to 4;A, B, D and E are each independently of the others N or CH, with the proviso that not more than two of those radicals are N;G is lower alkylene, -CH2-O-, -CH2-S-, -CH2-NH-, oxa (-O-), thia (-S-) or imino (-NH-), or is lower alkylene substituted by acyloxy or by hydroxy;Q is lower alkyl, especially methyl;R is H or lower alkyl;X is imino, oxa or thia;Y is lower alkyl or, especially, aryl, heteroaryl or unsubstituted or substituted cycloalkyl; andZ is amino, mono- or di-substituted amino, halogen, alkyl, substituted alkyl, hydroxy, etherified or esterified hydroxy, nitro, cyano, carboxy, esterified carboxy, alkanoyl, carbamoyl, N-mono- or N,N-di-substituted carbamoyl, amidino, guanidino, mercapto, sulfo, phenylthio, phenyl-lower alkylthio, alkylphenylthio, phenylsulfinyl, phenyl-lower alkylsulfinyl, alkylphenyl-sulfinyl, phenylsulfonyl, phenyl-lower alkanesulfonyl or alkylphenylsulfonyl, and where, if more than one radical Z is present (m>=2), the substituents Z are identical or different;and wherein the bonds indicated by a wavy line are either single bonds or double bonds;or an N-oxide of the mentioned compound, wherein one or more N atoms carry an oxygen atom;or a salt thereof. The compounds inhibit especially angiogenesis.
Patent EP-1115726-B1 (EP)
Inventor: PLATZEK JOHANNES
IPC: C07D487/22
Filed: 1999-08-20
Granted: 2002-11-27
Abstract: The invention relates to a method for preparing metalloporphyrin-metal complex conjugates, containing at least one ion of an element with an atomic number 20-32, 37-39, 42-51 or 57-83 in the complex fraction of the conjugate.
Patent EP-1141608-B1 (EP)
Inventor: MAUTE KURT PER
IPC: F16L21/00
Filed: 1999-12-15
Granted: 2004-10-13
Abstract: Arrangement for joining double-walled plastics pipes (9), manufactured with a smooth inner pipe (12) and a corrugated outer pipe (13) integrated with the inner pipe. To one end of the outer pipe is fastened a solid wall socket sleeve (1) with an inner surface arranged for holding a pipe end. This spigot sleeve (6) comprises a first solid wall spigot forming part (7A) which is inside and outside smooth, and an adjacent integrated solid wall sleeve forming part (7B) with an inside (10) which is mated to the outside of the plastics pipe (9), to be fastened tightly to this, by rotation welding.
Patent EP-1144459-B1 (EP)
Inventor: BARBUCCI ROLANDO
IPC: A61P19/00
Filed: 1999-11-08
Granted: 2002-10-02
Abstract: Cross-linked hyaluronic acids produced by the reaction of the carboxylic acid groups of hyaluronic acid and a polyamine and the sulfated and hemisuccinylated derivates thereof. The cross-linked hyaluronic acids are useful for various pharmaceutical and medical purposes.
Patent EP-1115385-B1 (EP)
Inventor: SCHAEKEN MATHIAS JOZEF MARIA
IPC: A61K9/70
Filed: 1999-09-23
Granted: 2005-04-13
Abstract: The present invention relates to a novel method for preventing or treating parodontitis. The method comprises treating a mammal having the disease with an antimicrobial composition comprising a physiologically acceptable varnish base and dissolved therein an antimicrobial agent.
Patent EP-1121472-B1 (EP)
Inventor: PREPARATA FRANCO P
IPC: B01J19/00
Filed: 1999-10-13
Granted: 2006-01-04
Abstract: The systems and methods described herein relate to nucleic acid probes comprising a pattern of universal and designate nucleotides, or "gapped" probes, and the use of sets of gapped probes in sequencing by hybridization to determine the sequence of nucleic acid sequences. The inclusion of universal nucleotides in the probes allows for efficient and rapid sequencing of longer nucleotide sequences than can be sequenced using traditional probes. The systems and methods described herein also relate to apparatus for sequencing nucleic acids which include gapped probes, as well as computer systems capable of analyzing data generated using gapped probes in such apparatus.
Patent EP-1155081-B1 (EP)
Inventor: YUAN CHIENKUO RONNIE
IPC: A23L29/10
Filed: 1999-10-08
Granted: 2004-02-25
Abstract: A method of producing high-amylose based starch-emulsifier compositions by heating a high-amylose starch in the presence of an emulsifier to form a complex with unique properties is described. High-amylose starch-emulsifier compositions (e.g., powders, gels, pastes) produced by this method and food products containing the high-amylose starch-emulsifier composition are also described.