baber/WOPTO huggingface dataset:
Patent EP-1181278-B1 (EP)
Inventor: TARBY CHRISTINE
IPC: A61P11/06
Filed: 2000-05-12
Granted: 2004-09-29
Abstract: This invention relates to novel arylalkyl cyclic amine derivatives. This invention also relates to chemokine receptor antagonists that are be effective as therapeutic agents and/or preventive agents for diseases such as atherosclerosis, rheumatoid arthritis, transplant rejection, psoriasis, asthma, ulcerative colitis, glomerulonephritis, multiple sclerosis, pulmonary fibrosis, and myocarditis, in which tissue infiltration of blood monocytes and lymphocytes plays a major role in the initiation, progression or maintenance of the disease. Furthermore, chemokine receptor antagonists also inhibit the interaction of viruses, which attack blood monocytes and lymphocytes, through the use of a chemokine receptor. One such example is the HIV virus.
Patent EP-1187549-B1 (EP)
Inventor: SOBLE JON
IPC: A61M25/00
Filed: 2000-05-26
Granted: 2008-09-10
Abstract: On décrit une gaine (10) destinée à être placée sur un endoscope souple (50). La gaine (10) comporte un orifice (20) situé entre ses ouvertures distale (15) et proximale (25), l'orifice (20) étant relié à une source de vide. Lorsque l'endoscope (50) est rentré en position proximale par rapport à l'orifice (20) d'aspiration, l'ouverture proximale (25) de la gaine est obturée et toute la gaine se transforme en lumière d'aspiration. Des dispositifs et des procédés selon la présente invention permettent d'améliorer l'évacuation de matières présentes dans des cavités corporelles, plus particulièrement des calculs dans les voies urinaires supérieures.
Patent EP-1216076-B1 (EP)
Inventor: DISSING STEEN
IPC: A61N2/04
Filed: 2000-08-28
Granted: 2006-08-16
Abstract: A method for stimulating growth in biological tissue or sprouts, an apparatus and a use thereof. The apparatus comprises of a pulse generator and a plurality of coils in which pulsed currents will cause fluctuating magnetic fields in a predetermined region holding the material to be stimulated. The fluctuating magnetic fields will induce an electric field in the material. An enhanced effect has been detected in the regions where the electric fields are largest. The coils comprise a number of pairs of coils having, during a given pulse, magnetic fields in opposite directions in order to provide field gradients in the cells, micro organisms or tissue. Selecting a suitable number, size and positioning of coils will provide a homogeneous electric field in the predetermined region, which does not have any undesirable peaked maxima. When four or more coils are used, they can be combined in pairs arranged on opposite sides of the predetermined region, and with the adjacent coils conducting current in opposite directions and the opposing coils conducting currents in the same direction. Thereby the induced electridal fields add constructively inside the regions between the pairs of coils. In an apparatus for stimulating cell proliferation and differentiation, it is a desired feature that the generated fluctuations in the magnetic fields does not elicit action potentials of living cells since this will cause great inconvenience for the patient.
Patent EP-1210327-B1 (EP)
Inventor: STEINMEYER ANDREAS
IPC: C07D333/22
Filed: 2000-07-24
Granted: 2006-01-18
Abstract: Vitamin D derivatives (I), having a cyclic substituent in the side-chain, are new. Also new are perhydroindane derivative intermediates (A) ands (B).  Vitamin D derivatives of formula (I), including all possible epimers, diastereomers and their mixtures, are new. Y1, Y2  =  H or -C(O)R5;  Y3 (in alpha- or beta-configuration)  =  H, OH, halo, OC(O)R5 or OR5;  R5  =  5-12C aromatic residue; or 1-12C optionally unsaturated alkyl (optionally interrupted by 1 or 2 O, 1 or 2 S and/or 1 or 2 NH; and optionally substituted by 1 or 2 OH, 1 or 2 NH2, 1 or 2 SH, 1 or 2 COOH and/or 1 or 2 COOH);  R1, R2  =  H or together form exocyclic =CH2;  R3, R4  =  H, F, Cl, Br or 1-4C alkyl;  or CR3R4  =  -C(=CH2)- or a 3-7 membered saturated or unsaturated carbocyclic ring;  Q  =  1-5C n-alkylene;  X1, X2  =  H, OH, OC(O)R5, F, Cl or Br (but not both OH or both -OC(O)R5);  or CX1X2  =  C=O;  Z'  =  carbocyclic or heterocyclic (including aromatic or heteroaromatic) ring system comprising a 5- or 6-membered ring optionally fused with a 6-membered ring (optionally substituted by one or more of each of halo, OH, COOR6 or 1-5C alkyl (itself optionally substituted by one or more of halo, 1-6C alkoxy and/or COOR6));  R6  =  1-6C alkyl, benzyl or phenyl. Independent claims are included for: (1) new perhydroindane derivative intermediates of formulae (A) and (B); (2) preparation of perhydroindane derivative intermediates of formula (XIIIa) by: (a) reacting a perhydroindane derivative of formula (A; T replaced by L) with protected, deprotonated propargyl alcohol to give (A; T = -CC-CH2OY5), (b) hydrogenating and deprotecting to give (A; T = -(CH2)3OH), (c) oxidizing to give (A; T = -CH2CH2CHO) and (d) reacting with a nucleophile Nu, cleaving Y4 and oxidizing the free OH group; and (3) preparation of vitamin D compounds of formula (IIa) by: (a) reacting a ketone of formula (XIIIb) with a trimethylsilyl acetoacetate ester in presence of a base or with a Wittig reagent in an aprotic solvent to give (B; U = COOR6), (b) reducing to give (B; U = CH2OH), (c) converting into (B; U replaced by L), (d) converting into the Wittig reagent (B; U = CH2P(O)(G)2) and (e) reacting with a ketone of formula (XXXIII) and optionally deprotecting the product.  T  =  -CC-CH2OY5, -(CH2)3OH or -CH2CH2CHO;  Y4  =  trialkylsilyl, mixed aryl-alkyl substituted silyl, tetrahydropyranyl or tetrahydrofuranyl protective group;  Y5  =  tetrahydropyranyl or benzyl;  E  =  side-chain, in which any keto and/or hydroxy groups are protected;  U  =  COOR6, CH2OH or CH2P(O)(G)2;  Y6  =  1-6C alkyl, benzyl or phenyl;  G  =  1-10C alkyl, 1-10C alkoxy, Ph or OPh;  L  =  leaving group;  Nu  =  nucleophile;  R7, R8  =  H or Me; or together form exocyclic =CH2 or a cyclopropane ring;  Y6  =  F, (CH2)nOH or (CH2)nOCOR5;  n  =  0-4;  Y'1  =  hydroxy-protecting group;  Y'3  =  H, halo or as Y'1.
Patent EP-1222659-B1 (EP)
Inventor: GERSHO ALLEN
IPC: G10L19/14
Filed: 2000-09-20
Granted: 2005-11-16
Abstract: An enhanced low-bit rate parametric voice coder that groups a number of frames from an underlying frame-based vocoder, such as MELP, into a superframe structure. Parameters are extracted from the group of underlying frames and quantized into the superframe which allows the bit rate of the underlying coding to be reduced without increasing the distortion. The speech data coded in the superframe structure can then be directly synthesized to speech or may be transcoded to a format so that an underlying frame-based vocoder performs the synthesis. The superframe structure includes additional error detection and correction data to reduce the distortion caused by the communication of bit errors.
Patent EP-1218481-B1 (EP)
Inventor: KVITA PETR
IPC: C11D1/645
Filed: 2000-09-26
Granted: 2005-10-19
Abstract: The present invention relates to a method of use of a softener composition for the antipilling treatment of textile fibre materials in domestic applications, which softener composition comprises : A) a fabric softener; B) at least one additive selected from the group consisting of a) a polyethylene, or a mixture thereof, b) a fatty acid alkanolamide, or a mixture thereof, c) a polysilicic acid, or a mixture thereof, and d) a polyurethane, or a mixture thereof; and C) a selected polyorganosiloxane compound.
Patent EP-1148976-B1 (EP)
Inventor: ZHANG LIMING
IPC: B24B37/04
Filed: 2000-10-02
Granted: 2005-03-09
Abstract: La présente invention concerne un système et un procédé facilitant le dépôt et la planarisation de plaquette au cours de la fabrication de plaquette de circuit imprimé. La présente invention facilite notamment le dépôt efficace de cuivre et la fabrication d'interconnexions entre les composants d'un circuit intégré. Le système de polissage de dépôt (200) et le procédé de la présente invention effectuent, en même temps, le dépôt de cuivre et le polissage. Dans l'un des modes de réalisation, ce système comprend un support (220) de plaquette, un tampon de polissage (230), ainsi qu'un bain galvanoplastique (235) appliqué par procédé mécanico-chimique. Le bain galvanoplastique (235) appliqué par procédé mécanico-chimique est un conteneur servant à contenir des bains (238) utilisés dans des procédés de galvanoplastie (par exemple, l'électrodéposition, le dépôt autocatalytique, etc.) pour déposer un matériau métallique (par exemple, du cuivre) sur une plaquette (224). Une plaquette (224) est placée dans le bain galvanoplastique (235) contenant un bain (238) de dépôt galvanoplastique, et en même temps que le matériau métallique est déposé sur la plaquette (224), le tampon de polissage (230) empêche le matériau de se déposer sur des portions de la surface de la plaquette (par exemple, une tranchée d'interconnexion (225)). Le tampon de polissage facilite également le transport du bain (238) de dépôt galvanoplastique vers la plaquette, le déplacement du tampon de polissage (230) agitant le bain (238) de dépôt galvanoplastique.
Patent EP-1244438-B1 (EP)
Inventor: COLLIER ROBERT J JR
IPC: A61K31/165
Filed: 2000-11-29
Granted: 2003-11-12
Abstract: Compositions and methods for treating disorders of the outer retina with β-adrenoceptor antagonists are disclosed.
Patent EP-1238489-B1 (EP)
Inventor: RABENKO THEODORE F
IPC: H04N7/24
Filed: 2000-12-13
Granted: 2008-03-05
Abstract: In one aspect of the present invention, a network gateway is configured to facilitate on line and off line bi-directional communication between a number of near end data and telephony devices with far end data termination devices via a hybrid fiber coaxial network and a cable modem termination system. The described network gateway combines a QAM receiver, a transmitter, a DOCSIS MAC, a CPU, a voice and audio processor, an Ethernet MAC, and a USB controller to provide high performance and robust operation.
Patent EP-1350096-B1 (EP)
Title: Dispositif de commande pour un systeme electro-optique
Inventor: SANCHEZ JORGE
IPC: H04B10/158
Filed: 2000-12-22
Granted: 2011-06-22
Abstract: La présente invention concerne un appareil et des procédés d'étalonnage utilisés pour commander un système électro-optique. L'appareil comprend un dispositif de commande qui inclut toute l'électronique nécessaire requise pour exciter le laser, surveiller son fonctionnement à l'aide de circuits de mesure, maintenir les paramètres du laser fonctionnant dans des limites acceptables au niveau des variations de la température et du dispositif et pour également commander le fonctionnement de circuits associés tels que des amplificateurs de signal et une interface d'ordinateur hôte. L'appareil comprend un amplificateur de signal qui permet au laser d'être entraîné par des signaux CC aussi bien que CA. L'invention concerne des procédés d'étalonnage du système laser. Les procédés consistent premièrement à caractériser et à étalonner le système avec un processus d'étalonnage effectué dans l'usine de fabrication. Ensuite, sur place, le système utilise les résultats obtenus lors de l'étalonnage en usine en même temps qu'un processus d'étalonnage sous tension afin d'atteindre une efficacité qui peut correspondre aux besoins stricts dans les domaines de la précision et de la fiabilité. Le processus comprend également un procédé de surveillance et d'ajustement en continu du laser pour compenser les éventuelles variations dues à la température ou au vieillissement par le biais de la mesure des variables de surveillance de l'efficacité du laser, au moyen des modèles appropriés et de techniques d'ajustement et enfin, en effectuant les ajustements alors que le laser est en utilisation, c'est-à-dire sans qu'il soit nécessaire de déconnecter le laser du système. Cette invention concerne des procédés qui suivent un processus détaillé de manière à permettre à une personne de construire un système dont on peut démontrer qu'il est étalonné dans des limites prédéfinies de précision comme l'exige une conception réalisée au moyen des idées de l'invention dans le cadre d'une application spécifique.
Patent EP-1263387-B1 (EP)
Inventor: POLZIN ULF
IPC: A61J1/05
Filed: 2000-11-29
Granted: 2004-09-15
Abstract: The unit for reconstitution of injection liquids and their subsequent injection comprises a slidable stop (92) which is bringable against the rear surface of the piston (90), and an element (91) which is slidable relative to the stop (92). The element (91) is joined to the piston in such a way that forces in either direction can be applied to the latter. An independent claim is included for a method of using the proposed unit. It involves introduction of the liquid (49) from the cartridge (50) into a container with a lyophilized reconstitution component, and extraction of the reconstituted liquid back into the cartridge.
Patent EP-1132132-B1 (EP)
Inventor: BAUER FRANK DR
IPC: C07C67/36
Filed: 2001-01-10
Granted: 2004-04-21
Abstract: Transition metals may be recovered from a salt-containing mixture containing at least one transition metal compound, salts, and organic compounds by separating from the salt-containing mixture a mixture of the transition metal compound and the salts. This mixture, together with any organic impurities, is introduced into a combustion zone, and the flue gas/salt mixture leaving the combustion zone is quenched with water. The combustion residue, containing the transition metal, is separated from the resulting quench solution, dried, and converted to fresh catalyst.
Patent EP-1205393-B1 (EP)
Inventor: SAUER RAINER DR
IPC: B21D51/38
Filed: 2001-09-07
Granted: 2005-05-04
Abstract: The lid includes a ring (1) attached to a can and formed with a lid opening (5) surrounded with a flange (4). The flange has upper web portion folded outward over a lower web portion, in which both web portions are flatted together. A detachable lid membrane (2), having peripheral edge (6) in contact with the abutting edge (3) of the flange upper web portion, seals the lid opening. An Independent claim is also included for the can sealing method.
Patent EP-1346982-B1 (EP)
Inventor: NAKAYAMA ATSUSHI
IPC: A61P29/00
Filed: 2001-12-28
Granted: 2011-09-14
Abstract: L'invention concerne des composés représentés par la formule générale (I) ou des sels de ceux-ci, ainsi que des médicaments contenant ces composés ou ces sels : (I) [dans laquelle W représente W?A-A1-WB- (WA¿ représente un aryle éventuellement substitué ou un composant analogue ; A1 représente  NR1-, une liaison simple, -C(O)-, ou un composant analogue ; et WB représente l'arylène éventuellement substitué ou un composant analogue) ; R représente une liaison simple, -NH-, -OCH¿2?-, alcénylène ou un composant analogue ; X représente -C(O)-, -CH2- ou un composant analogue ; et M représente p. ex. un groupe représenté par la formule générale (iii):  (iii) (dans laquelle R?11, R12 et R13¿ représentent chacun indépendamment les uns des autres hydrogène, hydroxyle, amino, halogéno ou analogues ; R14 représente hydrogène ou un alkyle inférieur ; Y représente  CH¿2?-O- ou analogues ; Z représente l'arylène éventuellement substitué ou analogues ; A?2¿ représente une liaison simple ou analogue ; et R10 représente hydroxyle ou alcoxy inférieur)]. Ces composés ou ces sels inhibent sélectivement la liaison des molécules d'adhésion cellulaire avec VLA-4 et présentent un degré d'absorption élevé par voie orale, et sont par conséquent utiles en tant que médicaments préventifs et/ou curatifs pour les maladies inflammatoires, les maladies auto-immunes, les métastases cancéreuses, l'asthme, l'occlusion nasale, le diabète etc.
Patent EP-1138264-B1 (EP)
Inventor: HOUSER KEVIN L
IPC: A61B18/00
Filed: 2001-03-30
Granted: 2007-05-23
Abstract: The present invention is directed to an ultrasonic surgical blade including a top surface, a bottom surface and a cutting-edge.The cutting-edge is defined by a cutting-surface intermediate the top surface and the bottom surface, and the top surface has a width greater than the width of the bottom surface. ., The blade may be straight or curved In one embodiment of the invention, at least a portion of the cutting-surface is substantially parallel to at least a portion of the top surface. In still another embodiment of the invention first and second side-walls intersect the top surface to form first and second cutting-edges that may be sharp or blunt. Alternately, a second cutting-edge may be defined by a second cutting surface intermediate the top and bottom surfaces. Depending on the angle between the intermediate cutting-surface and the top surface, the cutting-edge may be sharp or blunt. In yet another embodiment of the present invention, a central ridge is provided on the bottom surface of the blade to eliminate blade burrowing and improve precision during coagulation. The cutting-edge is optimized to increase cutting speed of the blade while providing desirable hemostasis. The invention is of particular benefit for breast surgery, due to its cutting and coagulation characteristics. <IMAGE>
Patent EP-1193137-B1 (EP)
Inventor: ARNAUD MATHIEU
IPC: B60R21/13
Filed: 2001-08-29
Granted: 2007-10-17
Abstract: A pair of roll over bars (13) are fixed rigidly at their lower ends to a structural feature (3) in the vehicle floor. The bars are flexed through a guide (25) to take up a normally retracted position in the risers (9) which support the windscreen and are held there by a restraining cable (15) fitted with a release which is activated when a sensor detects vehicle roll over
Patent EP-1225179-B1 (EP)
Inventor: ROYO GRACIA PASCUAL
IPC: C08F10/00
Filed: 2001-01-18
Granted: 2004-04-14
Abstract: 1. The invention concerns olefin polymerization catalyst component comprising an organometallic compound of general formula I <CHEM>  wherein:   M is a transition metal of groups 3, 4-10, lanthanide or actinide of the periodic table of the elements; each R is independently a structural bridge rigidly connecting two ligands L1, L2 and L3 and is constituted by 1 to 4 chain atoms selected from carbon, silicon, germanium, oxygen, boron; m, n and o are 0 or 1, with the proviso that m+n+o is 2 or 3; L1 is a ligand of the cyclopentadienyl type or is isolobal to cyclopentadienyl, L2 is a ligand of the cyclopentadienyl type or is isolobal to cyclopentadienyl, or a monovalent anionic ligand selected from the group consisting of N, P, B when m+n =2, it is selected from the group consisting of NR<1>, PR<1>, BR<1>, O and S when m+n =1; L3 is a monovalent anionic ligand selected from the group consisting of N, P, B when n+o =2, it is selected from the group consisting of NR<1>, PR<1>, BR<1>, O and S when n+o =1; R<1> is hydrogen, C1-C20 alkyl, C3-C20 cycloalkyl, C6-C20 aryl, C3-C20 alkenyl, optionally comprising 1 to 5 heteroatoms such as Si, N, P, O, F, Cl, Br; each X is independently selected from the group consisting of hydrogen, halogen, NR<2>2, R<2> with R<2> equal to C1-C20 alkyl, C1-C20 alkyl, C3-C20 cycloalkyl, C6-C20 aryl, C3-C20 alkenyl, optionally comprising 1 to 5 heteroatoms such as Si, N, P, O, F, Cl, Br; q is a number whose value is: 0, 1, 2 or 3, depending on the valence of the metal M; D is a neutral Lewis base, p is a number whose value is: 0, 1, 2 or 3.   The invention also concerns catalysts comprising compounds of formula (I) and the polymerization process making use of a catalyst comprising the claimed compounds.
Patent EP-1192915-B1 (EP)
Inventor: VON WEISSENFLUH BEAT A
IPC: A61C5/88
Filed: 2001-09-18
Granted: 2005-07-27
Abstract: Interdental wedge comprises a combination of a wedge body and a compressible base (3) having an edge (4) protruding on both sides of the wedge body. Preferred Features: The base is made of a material which changes from a non-compressible state to a compressible state on the application of force. Further compression increases super proportionally to compression. The base is made of a thermoplastic elastomer provided with a light-scattering substance and the wedge body is made of a light-impermeable plastic.
Patent EP-1159029-B1 (EP)
Inventor: SAGE BURTON H JR
IPC: A61M31/00
Filed: 2001-01-10
Granted: 2006-11-08
Abstract: The present invention relates to a non-invasive method and apparatus for pre selecting the drug delivery profile of a drug by controlling the concentration of ions added to or present in the reservoir containing the drug to be delivered, which ions would compete with the drug ions for the current. The administration of drug is carried out by means of iontophoresis.
Patent EP-1287282-B1 (EP)
Inventor: UDHOEFER ANDREAS
IPC: F16L19/10
Filed: 2001-03-03
Granted: 2004-11-10
Abstract: A screw connection including a sealing ring, a connecting piece, and a union nut for assembling a tube connector. The sealing ring has a nut side portion with an annular reinforcement on its outer face, a narrow ring portion, a ring surface with transfer elements arranged on its annular face located at the transition between the narrow ring portion and the nut side portion, and at least one cutting edge on its interior surface. The annular face having an inclination between 45° and 90° relative to the longitudinal axis of the tube connection. The connecting piece has an end face located at a first axial end and a conical bore disposed within. When fully assembled, the narrow ring portion is positioned with said conical bore, contacts the connecting piece, and transfers a negative image of the transfer elements on the ring surface onto the connecting piece end face.
Patent EP-1274870-B1 (EP)
Inventor: DEMIR ORHAN
IPC: C22B34/32
Filed: 2001-04-11
Granted: 2005-01-19
Abstract: A ferrochrome alloy is produced from an ore or concentrate by smelting the ore or concentrate in the presence of a reductant which is a carbide alone or a carbide in combination with another reductant. The carbide is preferably silicon carbide.
Patent EP-1268196-B1 (EP)
Inventor: CHOI CHUL WON
IPC: B29C48/07
Filed: 2001-03-29
Granted: 2004-09-22
Abstract: Il est possible d'améliorer le désaérage de stratifiés de polyvinylbutyral/verre, tout en réduisant le trouble dans la prépresse et en réduisant le temps mort, du fait qu'on utilise une feuille de polyvinalbutyral possédant une surface rugueuse à directionalité. On peut obtenir une surface rugueuse à motif de planche à laver par variation de certaines conditions du processus d'extrusion de marques de coulée.
Patent EP-1267960-B1 (EP)
Inventor: MOBERG SHELDON B
IPC: A61M5/168
Filed: 2001-03-28
Granted: 2006-05-10
Abstract: An occlusion detection system detects an occlusion in a fluid path of an infusion pump. The infusion pump is for delivering fluid to a user. The infusion pump includes a housing, a motor, a reservoir, one or more drive train components, a sensor, and an electronics system. The motor is contained within the housing. The reservoir contains the fluid to be delivered. The one or more drive train components react to stimulus from the motor to force the fluid from the reservoir into the user. The sensor is positioned to measure a parameter associated with the motor or a drive train component, and the sensor produces three or more output levels across a range of measurements. The electronics system processes the sensor output levels to declare when an occlusion exists.
Patent EP-1282379-B1 (EP)
Inventor: NAGAI KAZUTOSHI
IPC: A61B5/0205
Filed: 2001-05-08
Granted: 2005-03-23
Abstract: A biodata interfacing device includes a service console (1), an attachment storage compartment (3) defined in the service console (1) for accommodating a variety of sensors (31, 32, 33) used for collecting biodata, a lid (11) mounted on the service console (1) for opening and closing a top opening of the attachment storage compartment (3), and a display unit (12) formed on an upper surface of the lid. <IMAGE>