baber/WOPTO huggingface dataset:
Patent MA-38814-B2 (MA)
Title: Agoniste gitr et antagoniste pd-1 pour leurs utilisations dans le traitement de troubles proliferatifs
Inventor: GU DANLING
IPC: A61P35/00
Filed: 2014-08-18
Abstract: L'invention concerne des méthodes de traitement de troubles prolifératifs. En particulier, l'invention concerne une polythérapie à l'aide d'un agoniste gitr et d'un antagoniste pd-1.
Patent CS-227305-B2 (CS)
Title: Method of preparing heterocyclic oxypropanolamine derivatives
Inventor: FRIEBE WALTER GUNAR DR
IPC: C07D209/42
Filed: 1980-02-15
Abstract: The present invention provides heterocyclic oxypropanol derivatives of the general formula:   <IMAGE>   wherein R1 is a hydrogen atom or a lower alkyl, aralkyl or lower alkanoyl radical, R2 and R3, which can be the same or different, are hydrogen atoms or lower alkyl, hydroxyalkyl, alkoxycarbonyl or alkanoyloxyalkyl radicals or together represent an alkylene radical, R4 is a hydrogen atom or a lower alkanoyl radical or an aroyl radical, R5 is a hydrogen atom or a lower alkyl radical or an aralkyl radical, R6 is a hydrogen atom or a lower alkyl radical, R7 is a hydrogen atom, a hydroxyl group or a lower alkyl radical, Z is a valency bond, a methylene radical or an oxygen or sulphur atom, Ar is a carbocyclic aryl radical or a pyridyl radical, R8, R9 and R10, which can be the same or different, are hydrogen or halogen atoms, hydroxyl groups, lower alkanoyl radicals, lower alkyl radicals, lower alkenyl radicals, lower alkoxy radicals, aralkoxy radicals, allyloxy radicals, lower alkylthio radicals, aminocarbonyl radicals, aminosulphonyl radicals or lower alkanoylamino radicals or R8 and R9 together represent a lower alkylenedioxy radical or R7 and R8 together represent a -CH2-O- radical and A is -X1-Y1, in which X1 is a methylene or -NR11- radical, R11 being a hydrogen atom or a lower alkyl radical, and Y1 is a methylene radical or =C=Q, Q being an oxygen or sulphur atom; or A is -X2=Y2-, in which X2 and Y2, which can be the same or different and signify nitrogen atoms or =C(R12)- groups, R12 being a hydrogen atom or a lower alkyl or an alkoxycarbonyl radical, and when -X2=Y2- represents a -CH=N- group and R1 is an alkyl or aralkyl radical, because of the ability of indazole to tautomerise, this can also be localized on the nitrogen atom represented by Y2, with the proviso that Y1  or Y2 is joined to =N-R1 in general formula (I), and, when Q is an oxygen atom or -X2=Y2- represents -CR12=CR12- and Z is a valency bond or when -X1-Y1- represents   <IMAGE>  and Z is an oxygen atom or a valency bond, either the two symbols R2 and R3 do not simultaneously represent hydrogen atoms or R7 and R8 together must form a -CH2-O- radical; and the pharmacologically acceptable salts thereof. The present invention also provides processes for the preparation of these compounds and pharmaceutical compositions containing them. Furthermore, the present invention is concerned with the use of these compounds for the treatment of cardiac and circulatory diseases.
Patent AU-771838-B2 (AU)
Title: Network communication system
Inventor: KAWAI SHOSAKU
IPC: H04M11/00
Filed: 2000-01-18
Granted: 2004-04-01
Abstract: The object of the invention is to provide a network system capable of solving the problems above without applying excessive load to the host computer and enabling users to exchange views freely. The network communication system 1 comprises the host device 3, the first communication device 5, and the second communication device 7. The first communication device 5 in turn includes a primary connection information generating means 11, an identity information generating means 12, a major identity information generating means 13, and a transmitting means 14. The second communication device 7 includes a receiving means 15, a storage means 16, a display means 17, a selecting means 18, and a connecting means 19. Therefore, a network system capable of solving the problems above without applying excessive load to the host computer and enabling users to exchange views freely, is provided. <IMAGE>
Patent AU-729916-B2 (AU)
Title: Flow-resistant material additions to double-seam on-machine-seamable fabrics
Inventor: ELKINS PHILLIP R
IPC: D21F7/10
Filed: 1999-02-11
Granted: 2001-02-15
Abstract: An on-machine-seamable papermakers' fabric includes a first and a second base fabric, each of which is joined into endless form with a seam. The first and second base fabrics are attached to one another by at least one layer of staple fiber batt entangled therethrough such that they are offset with respect to one another in a lengthwise direction when so joined. As a consequence, seaming loops at one widthwise edge of the first base fabric coincide with a non-seam region of the second base fabric, and seaming loops at one widthwise edge of the second base fabric coincide with a non-seam region of the first base fabric. These coincident non-seam regions have additional flow-resistant material included so that when the on-machine-seamable papermakers' fabric is joined into endless form by closing both seams, it may, in the vicinities of the seams, have permeabilities to air and water substantially identical to the remainder of the fabric body thereof. Alternatively, the on-machine-seamable papermakers' fabric includes a multi-layered integrally woven base fabric having two systems of machine-direction yarns forming seaming loops in two distinct rows separated from one another in a thicknesswise direction of the fabric along each of its two widthwise edges. The two distinct rows are offset with respect to one another in a lengthwise direction of the base fabric. As a consequence, the seaming loops in one row coincide with a non-seam region of the base fabric at each widthwise edge thereof. The coincident non-seam regions, as above, have additional flow-resistant material. <IMAGE>
Patent AU-691904-B2 (AU)
Title: Use of a recombinant inhibitor from erythrina caffra for purifying serine proteases
Inventor: KOHNERT ULRICH
IPC: C12N15/09
Filed: 1995-03-13
Granted: 1998-05-28
Abstract: PCT No. PCT/EP95/00926 Sec. 371 Date Sep. 13, 1996 Sec. 102(e) Date Sep. 13, 1996 PCT Filed Mar. 13, 1995 PCT Pub. No. WO95/25168 PCT Pub. Date Sep. 21, 1995Process for purifying serine proteases from a protein mixture by binding the serine protease to an immobilized polypeptide with the activity of an inhibitor DE-3 from Erythrina caffra, removing unbound components from the protein mixture, detaching the serine protease from the inhibitor and separating the immobilized inhibitor from the soluble serine protease and isolating serine protease which is characterized in that a polypeptide is used as the polypeptide which is the product of a prokaryotic or eukaryotic expression of an exogenous nucleic acid. This inhibitor is distinguished by an improved specific activity and is particularly suitable for the purification of plasminogen activators such as tissue plasminogen activators (t-PA and derivatives).
Patent AU-693205-B2 (AU)
Title: Method for synchronizing subscriber equipments, a base station and a subscriber equipment
Inventor: OJANPERA TERO
IPC: H04B1/707
Filed: 1995-05-29
Granted: 1998-06-25
Abstract: A base station, a subscriber equipment, and a method for synchronizing the subscriber equipment with the transmission of the base station in a digital cellular radio network utilizing the CDMA multiple access method. In each cell of the network, at least one base station communicates with the subscriber equipment within its area, in which network the base station transmits a separate pilot channel provided with a predetermined spreading code. In order to facilitate the synchronization of the subscriber equipment, the base station transmits a data-modulated signal on the pilot channel.
Patent AU-656230-B2 (AU)
Title: Cyclic vasoactive peptides
Inventor: BOLIN DAVID ROBERT
IPC: A61K38/08
Filed: 1992-10-06
Granted: 1995-01-27
Abstract: The present invention relates to vasoactive peptide (VIP) analogs wherein the side chain carboxy terminus of one amino acid in the peptide chain is attached covalently to the side chain amino terminus of another amino acid in the peptide chain via the formation of an amide bond. The covalent bonding between the two amino acid residues in the peptide chain yields a ring structure. The present invention provides cyclic vasoactive peptides and pharmaceutical compositions comprising such a cyclic vasoactive peptide for the treatment of bronchotracheal constrictive disorders.
Patent AU-657171-B2 (AU)
Title: An (in vitro) method of evaluating the effects of a substance
Inventor: NILSSON STEFAN
IPC: G01N33/50
Filed: 1992-10-06
Granted: 1995-03-02
Abstract: PCT No. PCT/SE92/00698 Sec. 371 Date Apr. 6, 1994 Sec. 102(e) Date Apr. 6, 1994 PCT Filed Oct. 6, 1992 PCT Pub. No. WO93/07290 PCT Pub. Date Apr. 15, 1993An in vitro method of evaluating the antagonistic versus agonistic effects of a receptor-binding test substance on a selected type of cells containing endogenous intra-cellular hormone receptors, is disclosed. Said test substance, and separately a reference substance, known to be either an antagonist or an agonist, are incubated with said selected type of cells, and the magnitude of the selected cellular response resulting from hormone/receptor interaction, is analyzed. In case the method is performed on at least two selected types of cells which derive from different kinds of tissues, it is possible to evaluate the pattern of antagonistic versus agonistic effects of the selected test substance on said kinds of tissues.
Patent AU-571883-B2 (AU)
Title: Distribution transformer
Inventor: ALEXANDROV NICOLAI
IPC: H01F41/06
Filed: 1984-08-08
Granted: 1988-04-28
Abstract: A distribution transformer and a method of making same. The transformer has at least one closed magnetic circuit in the form of a hollow toroidal coil made from ferro-magnetic steel ribbon. An electric circuit is formed by a primary winding and a secondary winding each constituted by one or more sub-assemblies in the form of a double pancake. These double pancakes are juxtaposed and molded together in a solid insulating material to form a rigid insulating frame on which the magnetic circuit is wound to form one or more magnetic coils. The rigid insulating frame, which is constituted by the primary and secondary windings and the insulating material, also includes therein conduits capable of circulating a cooling fluid through the windings whereby to provide heat exchange to cool the assembly of the electrical and magnetic circuits.
Patent AU-692126-B2 (AU)
Title: Multi-layer containers
Inventor: SLAT WILLIAM A
IPC: B29B11/06
Filed: 1997-07-31
Granted: 1998-05-28
Abstract: A multi-layer preform for forming multi-layer containers includes an extruded upper portion having a first thickness which is adapted to form an upper portion of a container. The preform also includes an extruded intermediate portion having a second thickness thicker than the first thickness. The intermediate portion is connected with the upper portion and is adapted to form an intermediate body portion of the container. The preform also includes an extruded base portion having a third thickness thicker than the second thickness. The base portion is connected with the intermediate portion and is adapted form a base portion of the container. The portions of the preform are preferably formed from an inner layer and a barrier layer wherein the layers are co-extruded for forming the preform and an outer injection molded layer. In one embodiment, the inner layer includes a lip which overlaps the top edge of the barrier and outer layers. A multi-layer container is then formable from blow molding the preform.
Patent AU-692300-B2 (AU)
Title: 2,3-dihydro-1-(2,2,2-trifluoroethyl)-2-oxo-5-phenyl-1h-1, 4-benzodiazepines
Inventor: CLAREMON DAVID A
IPC: A61K31/551
Filed: 1995-08-17
Granted: 1998-06-04
Abstract: This invention is concerned with novel compounds represented by structural formula I    <IMAGE>  I  where X and Y are independently hydrogen, chloro, fluoro, bromo, iodo, or trifluoromethyl and n is 0, 1 or 2; R is hydrogen, fluoro, chloro, bromo, iodo, or trifluoromethyl, methyl, or methoxy; and the racemates, mixtures of enantiomers, individual diastereomers or individual enantiomers with all isomeric forms and pharmaceutically acceptable salts, hydrates or crystal forms thereof, which are antiarrhythmic agents.
Patent AU-778166-B2 (AU)
Title: Bacterial ghosts as carrier and targeting vehicles
Inventor: LUBITZ WERNER
IPC: A61K9/50
Filed: 2000-03-03
Granted: 2004-11-18
Abstract: The invention concerns the use of bacterial ghosts as carrier and targeting vehicles for active substances.
Patent AU-667217-B2 (AU)
Title: Novel phospholipase A1, processes for its preparation and the use thereof
Inventor: HATTORI ATSUSHI
IPC: C12N9/20
Filed: 1993-06-16
Granted: 1996-03-14
Abstract: A Phospholipase A1 which is capable of hydrolysing a phospholipid to produce a 2-acyl lysophospholipid and is obtainable from species of the fungus Aspergillus.
Patent AU-780349-B2 (AU)
Title: Cardiac motion tracking using cine harmonic phase (HARP) magnetic resonance imaging
Inventor: PRINCE JERRY L
IPC: A61B5/055
Filed: 2000-04-14
Granted: 2005-03-17
Abstract: The present invention relates to a method of measuring motion of an object such as a heart by magnetic resonance imaging. A pulse sequence is applied to spatially modulate a region of interest of the object and at least one first spectral peak is acquired from the Fourier domain of the spatially modulated object. The inverse Fourier transform information of the acquired first spectral-peaks is computed and a computed first harmonic phase image is determined from each spectral peak. The process is repeated to create a second harmonic phase image from each second spectral peak and the strain is determined from the first and second harmonic phase images. In a preferred embodiment, the method is employed to determine strain within the myocardium and to determine change in position of a point at two different times which may result in an increased distance or reduced distance. The method may be employed to determine the path of motion of a point through a sequence of tag images depicting movement of the heart. The method may be employed to determine circumferential strain and radial strain.
Patent AU-581228-B2 (AU)
Title: Method and apparatus of manufacturing a body of a container, same body and same container
Inventor: GLERUM JOHANNES ADRIAAN IR
IPC: B21D22/28
Filed: 1985-05-30
Granted: 1989-02-16
Abstract: The invention relates to a method of manufacturing a body (2) for a container, in which a body (2) having a weldseam (11) along its longitudinal direction is formed by bending material in sheet form and welding the overlapping edges of the bended material together, and the wall of the body having the longitudinal weldseam (11) is thinned.Preferably thinning is obtained by wall-ironing. It is advantageous that the wall thickness of a wall part close to wall end of the body is larger than that of a remaining part of the body and eventually prior to thinning has been reduced and that prior to being reduced the body is provided with a gripping rim (18) and/or cover (20).
Patent AU-616822-B2 (AU)
Title: Memory gauge
Inventor: ANDERSON TERRY OWEN
IPC: E21B47/00
Filed: 1989-11-30
Granted: 1991-11-07
Abstract: A downhole self-contained memory gauge includes either a semiconductor or magnetic core memory for retaining downhole information related to sampled parameters, such as borehole temperature and pressure. A microprocessor-based computer manages the power utilization by independently and selectably energizing and de-energizing different sections of the gauge. The magnetic core memory is tested for operability, and the addressing of the magnetic core memory is adjusted in accordance with any inoperable memory locations. Samples of the monitored environmental conditions can be taken at variable rates dependent upon software monitoring of the condition, the remaining battery life and the remaining memory capacity and in response to hardware monitored pressure changes. Each sample can be taken to a selectable resolution. A watchdog circuit monitors the microprocessor to ensure that it is operating within a preselected time limit.
Patent AU-765804-B2 (AU)
Title: Drive sprocket with relief areas
Inventor: WOYACH DENNIS
IPC: B65G23/06
Filed: 2000-04-27
Granted: 2003-10-02
Abstract: A drive sprocket for use with a belt module having a lower surface, and a pocket formed in the lower surface having a drive surface and a recessed surface includes a base having an outer periphery rotatable about an axis, and a plurality of teeth extending radially from the outer periphery. Relief areas formed between the teeth collect particles falling from the belt. At least one tooth includes a drive surface for engaging the module drive surface, and a top. Tooth sides extend from the top and toward said base.
Patent AU-672996-B2 (AU)
Title: Antiseptic polymer
Inventor: CHATELIN ROGER
IPC: D06M13/322
Filed: 1993-09-23
Granted: 1996-10-24
Abstract: Polymer with antiseptic property, obtained using, during a polymerisation reaction, a monomer of general formula: <IMAGE>  in which:   a) R1 and R2 are alkyl groups, CaH2a+1 for R1 and CbH2b+1 for R2, respectively, and R3 is either an alkyl group CcH2c+1 with c >/= 4 and 15 >/= a+b+c >/= 6 or an aryl group of formula -(CH2)d-C6H5 with d >/= 1 and a+b+d </= 8   b) 3 >/= n >/= 1 c) A is an ethylene functional group capable of participating in a polymerisation reaction d) X<(-)> is an anion. ng
Patent AU-522824-B2 (AU)
Title: Loom projectile
Inventor: CYVAS PETRAS
IPC: D03J5/06
Filed: 1979-10-17
Granted: 1982-06-24
Abstract: A projectile (10) for use in a loom in which filling picks are inserted from an outside supply sourse comprises an elongate body (12) having an inlet opening (28) at one end, an outlet opening (30) at the opposite end thereof and an outer wall defining the outer shape of the body. A perforated inner wall (16) defines a generally flat filling storage chamber (18) within the body, the storage chamber being connected to the inlet opening, and a passageway (44) is located between the inner and outer walls. The passageway is connected to the outlet opening and to the storage chamber by the perforations (42) in the inner wall.
Patent AU-771307-B2 (AU)
Title: Identification and functional characterization of a novel ribosomal S6 protein kinase
Inventor: GOUT IVAN
IPC: G01N33/53
Filed: 1999-08-04
Granted: 2004-03-18
Abstract: A novel S6 kinase, p70 beta <S6k>, is described, along with methods of making and using p70 beta <S6k> and related nucleic acids. The invention also discloses methods of identifying agents which modulate the activity of p70 beta <S6k> and/or its ligands.
Patent AU-716980-B2 (AU)
Title: Cryogenic polishing method for soft acrylic articles
Inventor: LEWELLEN KEVIN
IPC: B24B13/00
Filed: 1997-10-31
Granted: 2000-03-16
Abstract: A method for polishing articles comprising soft acrylic materials is disclosed. The method includes a cryogenic polishing step and a cleaning step. In the polishing step, a receptacle is charged with polishing beads of various sizes, sodium bicarbonate, a swelling agent and the articles to be polished, for a period of time and at a rotation speed sufficient to remove surface irregularities. Following the polishing step, a receptacle is charged with (a) a cleaning slurry comprising cleaning beads of various sizes and (i) sodium hydroxide and water or (ii) alumina, a surfactant and a solvent and (b) the articles to be cleaned, for a period of time and at a rotation speed sufficient to clean the surface of the polished articles. Agitation is preferably accomplished by a tumbling machine.
Patent AU-585007-B2 (AU)
Title: A contact sensor for measuring dental occlusion
Inventor: MANESS WILLIAM
IPC: A61C19/05
Filed: 1986-03-28
Granted: 1989-06-08
Abstract: A contact sensor for detecting points on a grid where the sensor is being contacted on opposing sides by teeth surfaces or other contacting points. The contact sensor includes two sets of parallel electrodes which are each formed of a thin, flexible supporting sheet. The electrodes are coated with a thin, resistive coating. Two such electrode structures are oriented at approximately right angles to create a grid where the intersecting electrodes cross separated by the resistive coatings. The resistive coatings may be made from conventional resisitive inks and are optionally separated by a separation material, such as talcum or mesh. In the absence of an external force, the material between the electrodes sets provides a high resistance between intersecting electrodes. The novel composition of the intermediate layer results in a structure which provides a "switching" effect such that the resistance between electrodes is very high where there is no external pressure and changes to a comparatively low value at locations where external pressure is applied by two contacting points or surfaces. The sensor output is dynamic in the sense that the resistance will change back and forth between high and low resistance states as external pressure is repeatedly applied and removed. The sensor may be made extremely thin and can provide high resolution capable of distinguishing between contact points separated by 0.050 inches or less. Additionally, the sensor output may be provided by means of a small computer or similar digital processor which monitors the signals from the sensor grid and which provides an output which indicates the variation in contacting points with time.
Patent AU-648988-B2 (AU)
Title: Wire connector for cable wires, in particular of telecommunication cables
Inventor: GERKE DIETER
IPC: H01R4/24
Filed: 1990-08-31
Granted: 1994-05-12
Abstract: Conventional wire connectors for cable wires, especially of telecommunications cables. Wire connectors have a housing lower part with the guide channels and insulating-piercing contact elements for holding the two wire pairs, as well as at least one housing upper part, constructed as a cover, with webs for pressing the cable wires into the insulating-piercing contact elements of the housing lower part. The disadvantage in this case is the high production cost for the different housing parts. 
<??>The invention provides that two housing parts 2, 2' are of identical construction and latch to one another, rotated through 180 DEG with respect to one another, that the webs 6, 7 form the pressing-in webs between the guide channels 8, 9, that the latching elements are formed from the side walls 4, 5 of the housing parts 2, 2' running parallel to the guide channels 8, 9, and that a retaining groove 11 for the other, shorter side wall 5 of the housing parts 2, 2' is constructed on the inside of the longer side wall 4. 
<IMAGE>
Patent AU-642695-B2 (AU)
Title: Process for the preparation of binary sulphur compounds
Inventor: COLOMBET PIERRE
IPC: C01F17/00
Filed: 1991-01-30
Granted: 1993-10-28
Abstract: Process for the synthesis of binary sulphur compounds, such as rare-earth and transition metal sulphur compounds. 
<??>This process consists in reacting a rare-earth compound, for example oxide or carbonate, or a transition metal oxide with a sulphur carbon compound such as CS2, in a closed vessel at a pressure of between 1 x 10<5> Pa and 150 x 10<5> Pa. 
<??>The products obtained are either rare-earth higher sulphides or rare-earth sesquisulphides.