baber/WOPTO huggingface dataset:
Patent CA-2559095-A1 (CA)
Inventor: HELLERSTEIN MARC K
IPC: G06F19/00
Filed: 2005-03-11
Abstract: Cette invention concerne des procédés utilisés pour établir le moment et l'emplacement spatial d'un événement de biosynthèse dans un organisme vivant, sans perturber ledit événement ni ledit organisme vivant. Un gradient temporel ou spatial d'un précurseur biochimique présentant un marquage isotope est crée. Ce gradient permet d'établir des empreintes isotopiques (c'est-à-dire, de marquer définitivement) au moment ou à l'endroit où intervient la biosynthèse. Les procédés décrits dans cette invention peuvent être largement appliqués à une vaste gammes d'applications médicales, de santé publique, et diagnostiques, ainsi que pour établir des séquences d'événements biochimiques se produisant dans un organisme vivant.
Patent CA-2565135-A1 (CA)
Inventor: BENNETT DEAN ALLEN
IPC: E21B33/06
Filed: 2005-02-18
Abstract: A blowout preventer comprising a body (12) with a bore therethrough, a ram and a ram block (30) characterised in that said blowout preventer further comprises an apparatus (40) secured to the blowout preventer for selectively engaging and supporting the ram block (30) and moving the ram block (30) with respect to the ram.
Patent CA-2565148-A1 (CA)
Title: Starved air inclined hearth combustor
Inventor: MCCARTHY JOSEPH W
IPC: F23G5/16
Filed: 2005-05-13
Abstract: An inclined hearth combustor which generally includes a primary combustion chamber having a plurality of stepped hearths, a secondary combustion chamber in communication with the primary combustion chamber and a boiler having an inlet in communication with the secondary combustion chamber.
Patent CA-2565159-A1 (CA)
Title: Taste-masked formulations containing sertraline and sulfoalkyl ether cyclodextrin
Inventor: MOSHER GEROLD L
IPC: A61K31/724
Filed: 2005-04-19
Abstract: The present invention provides aqueous oral formulations containing sertraline, or a pharmaceutically acceptable salt thereof, and a sulfoalkyl ether cyclodextrin. The liquid formulations are pleasant tasting, convenient to use, and chemically and physically stable. The liquid formulations can be administered directly or diluted before administration. Unlike the commercially available ZOLOFTTM formulation, the liquid formulations herein do not precipitate upon dilution with water, fruit juices, sodas or other pharmaceutically acceptable oral liquid carriers. The sulfoalkyl ether cyclodextrin-containing formulation provides significant advantages over the marketed non-aqueous formulation and other cyclodextrin-containing formulations of sertraline. The formulation can be self-preserved against microbial growth. The SAE-CD-containing formulation of sertraline can be provided in liquid form or as a reconstitutable powder. Both ready-to-use and concentrated liquid formulations can be prepared. The formulation is available as a clear solution or a suspension.
Patent CA-2566031-A1 (CA)
Title: Systems and methods for contact center analysis
Inventor: MURRAY EDWARD
IPC: G06Q10/06
Filed: 2006-10-30
Abstract: Systems and methods for providing integrated solutions for performing workforce management and quality monitoring utilizing an integrated data warehouse system are provided. In this regard, a representative method comprises:  generating data from a plurality of workforce optimization (WFO) applications, the WFO applications including, with respect to a workforce, forecasting, scheduling, training, and monitoring functionalities; storing the data in a database optimized for extracting the data therefrom; and performing management analytics by querying the database according to at least one usage application, wherein the usage application defines at least one analysis purpose.
Patent CA-2568504-A1 (CA)
Inventor: ZHAO JONATHON Z
IPC: A61L27/40
Filed: 2006-11-22
Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reacti on to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic agent s or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healin g, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including vulnerable plaqu e. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to contro l the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
Patent CA-2568951-A1 (CA)
Inventor: EYSYMONTT JAN
IPC: F04B43/113
Filed: 2005-06-02
Abstract: A hydraulically driven multicylinder diaphragm pumping machine for pumping difficult-to-pump materials comprises pump cylinders each having at one end (20) an inlet/outlet (21) for fluid material to be pumped supplied under adjustable pneumatic pressure, and at the other end (30) an inlet and outlet (31,32) for hydraulic oil. A separator (40) movable to-and-fro inside the pump cylinder (10) is connected to the fluid-material end of the cylinder by a bellows-like flexible diaphragm (45) and to the fluid material end (30) by another bellows-like diaphragm (46) leaving an outer annular space (49) that contains hydraulic fluid. The total volume of pumping hydraulic oil in the cylinders (10.1-10.12) is maintained constant and equal to 1/2 the total displacement volume of the cylinders by a device (65) that compensates for thermal expansion and controls the necessary return flow of hydraulic oil for driving the pump. The separators (40) move with an intake stroke at constant speed for all cylinders, and with pumping strokes function of the hydraulic oil delivery, so a lesser number of separators (40) effect an intake stroke while a greater number of separators (40) effect a discharge stroke.
Patent CA-2571348-A1 (CA)
Inventor: VITALIS TIMOTHY Z
IPC: A61K39/12
Filed: 2006-12-18
Abstract: Despite continued progress in understanding the pathophysiology of tumour progression and metastasis, curative therapeutic options are still missing for metastatic melanoma. Downregulation of MHC class I antigen expression is frequently associated with impaired transporter-associated-with-antigen-processing (TAP) expression in many tumours, including melanoma, making them invisible to effector cytotoxic T cells. One approach to making therapeutic vaccines is to use genetically engineered non-replicating viruses as vaccine vehicles to revive immunosurveillance mechanisms in order for tumours to be eradicated. A  perceived problem with this approach is that the number of nonreplicating viruses used as vaccine inoculum does not remotely approximate the total number of cells in the body, nor even the number of tumour cells in the case of large tumour burden or metastasis, leaving some to argue that this is a poor method of anti-cancer vaccination.  Here we addressed the hypothesis that a limited amount of inoculae (1 × 10 8) of recombinant non-replicating adenovirus encoding human TAP1(AdhTAP1) can induce protective immunity against (1.5 × 10 5) TAP-deficient, metastatic melanoma cells transplanted into a normal mouse (total of 1 × 10 11 body cells). We show that efficacious anti-tumour responses are indeed induced by injecting melanoma-bearing animals with small numbers of these recombinant viruses, resulting in increased animal survival and, importantly, in enhanced memory T cell subpopulations. These observations suggest that the inclusion of TAP in virus vaccines may promote and maintain long term anti-tumour responses even when the vector used to deliver TAP     only infects a small fraction of the metastatic tumour cells. This novel approach uses a limited input inoculae relative to the tumour cell mass, and thus achieves an efficacious outcome that has so far eluded other vaccine, immunotherapeutic or gene therapeutic strategies where there is a requisite for the majority of tumour cells to be transduced for beneficial outcome to be achieved.
Patent CA-2573466-A1 (CA)
Inventor: GABOURY SCOTT R
IPC: H01M8/10
Filed: 2005-06-22
Abstract: Multi-layer polyelectrolyte membranes are described wherein at least one of the layers contains at least one acrylic resin or vinyl resin having at least one ionic or ionizable group, and at least one additional polymer. The polymer has small or large domain sizes with respect to he acrylic resin or vinyl resin that is present in one or more layers. The polymer preferably has improved conductivity when formed formed into a film. The membranes are useful in batteries, fuel cells, and the like.
Patent CA-2573732-A1 (CA)
Title: Automated system of processing biological specimens and method
Inventor: LEFEBVRE GILLES
IPC: G01N1/30
Filed: 2007-01-11
Abstract: An automated laboratory slide management and interpretation system and method in which slides are stained and then digitally imaged and the images are interpreted prior to referral to a diagnostician or placement in storage. The interpretation of the images involves the application of pattern recognition principles to compare the digitized images to known sample patterns from a variety of sources. Additionally, based on the results of the interpretation, the slide may undergo additional testing or staining, and additional samples may be prepared and tested. The specimens may be delivered to the diagnostician along with a tentative diagnosis.
Patent CA-2574161-A1 (CA)
Inventor: BINLEY GARY NORMAN
IPC: A23G9/32
Filed: 2005-06-20
Abstract: La présente invention concerne un produit étanche contenant de la glace comprenant un premier type de particules congelées à 18°C présentant une granulométrie supérieure à 0,5 mm et un second type de particules congelées présentant une granulométrie moyenne telle que le rapport granulométrie moyenne du premier type de particules sur la granulométrie moyenne du second type de particules est supérieur à 10 et inférieur à 100. Le rapport pondéral entre les deux types de particules étant compris entre 2:3 et 9:1, le premier type et le second type de particules représentent ensemble au moins 90% des particules congelées se trouvant dans le produit. La présente invention concerne également un procédé permettant d'élaborer de tels produits
Patent CA-2574178-A1 (CA)
Title: Inductive position sensing device and method
Inventor: GLASSON RICHARD O
IPC: G01D5/16
Filed: 2005-07-21
Abstract: A field-altering device for an inductive sensor has an elongated body with a substantially saw-tooth profile. The body is made of steel or other type ferrous material. With use in a Hall-effect sensor, the body moves relative to the sensor causing the field to vary periodically with time. The sensor generates an electrical signal in dependence on the field variations, the electrical signal having a saw-tooth pattern.
Patent CA-2583852-A1 (CA)
Inventor: CARDOLLE FRANCIS
IPC: B62D35/02
Filed: 2007-04-04
Abstract: The present invention relates to a fairing for a trailer having a wheel assembly. The fairing is positioned on the underside of the trailer to cover a frontal area of the wheel assembly. More specifically, the fairing includes a shell and an anchoring mechanism. First, the shell is designed to cover the frontal part of the wheel assembly. Secondly, the anchoring mechanism allows attaching the shell to the trailer.
Patent CA-2587346-A1 (CA)
Title: Open vessel sealing forceps disposable handswitch
Inventor: TWOMEY JOHN R
IPC: A61B18/12
Filed: 2007-05-04
Abstract: A removable handswitch and electrode assembly for use with a forceps having opposing end effectors and a handle for effecting relative movement of the end effectors with respect to one another includes a housing having at least one portion which removably engages at least a portion of a mechanical forceps and a handswitch assembly disposed on the housing. A pair of electrodes is included which removably engage a distal end of the mechanical forceps such that the electrodes reside in opposing relation to one another.  At least one electrode is adapted to connect to an electrosurgical generator through the handswitch assembly. At least one stop member is operatively associated with the electrodes and controls the distance between the opposing electrodes to affect a tissue seal.
Patent CA-2587786-A1 (CA)
Inventor: LEAKE DEVIN
IPC: C12N15/87
Filed: 2005-11-21
Abstract: A reverse transfection apparatus can be used for introducing siRNA into a cell to effect gene silencing. Such an apparatus can include a well plate having a well configured for transfecting cells. The well can include a substantially dry gene silencing composition that has at least a first siRNA which silences a first target gene.  The gene silencing composition can be configured such that the at least first siRNA is capable of being solubilized or suspended in an aqueous medium in an amount sufficient for transfecting cells in the well. Additionally, the at least first siRNA can include a modification or a conjugate. The reverse transfection apparatus can be provided as a kit or system that additionally includes cells, polynucleotide carriers, reverse transfection reagents, and the like.
Patent CA-2593635-A1 (CA)
Title: Basic cell structure for fuel cell equipped with sealing means
Inventor: NIETSCH THOMAS
IPC: H01M8/02
Filed: 2007-07-03
Abstract: The invention makes it possible to provide a seal at the level of the contact between each membrane--electrode element (1) with the supply plates (10).     Sealing means produced either by means of a densification layer (20) or by means of a microporous material for forming the diffusion layers (3B, 4B), are arranged in the diffusion layers (3B, 4B) of the anode (3) and the cathode (4), respectively, opposite the open surface of the cooling channel (15) of each supply plate (10).     Application in PEM fuel cells.
Patent CA-2598957-A1 (CA)
Title: Process for high temperature solution polymerization
Inventor: CHELUGET ERIC
IPC: C08F2/01
Filed: 2007-08-27
Abstract: The current invention provides a method of improving the efficiency of one or more heat exchangers used in cooperation with a high temperature solution polymerization process. Addition of surface active agents, such as C6 to C22 carboxylic acids, to a two phase liquid-liquid polymer solution downstream of a reactor system and upstream of a heat exchanger system can increase the efficiency of heat exchange by more than 10%.
Patent CA-2600741-A1 (CA)
Inventor: VAN LOYEN DIETMAR
IPC: B65D51/22
Filed: 2006-03-23
Abstract: A container for regenerating salt for a dishwasher comprises a body (1) having a spout adapted to engage an inner periphery of a mouth of a dishwasher salt tank. The spout has a gate (2) operable by a user to allow the flow of salt.
Patent CA-2600875-A1 (CA)
Title: Production of activated char using hot gas
Inventor: CHAO CHIEN-CHUNG
IPC: C01B32/336
Filed: 2006-03-13
Abstract: A gas mixture preheated to high temperatures using an oxy-fuel, an oxygen-enriched air-fuel or an air-fuel burner is used to devolatilize and partially oxidize carbonaceous feedstock, thereby producing an active residual char that can be used in applications utilizing activated carbon. Use of hot gas and ground carbonaceous feedstock allows the equipment to be minimized, thereby allowing the activated carbon to be produced at or near points of use, for example the production of activated char at or near utility boilers for use in the reduction of mercury emissions from flue gas streams.
Patent CA-2601785-A1 (CA)
Title: Network commercial transactions
Inventor: WEBSTER-LAM CHUNG
IPC: H04W12/10
Filed: 2006-04-19
Abstract: Current embodiments provide for authorization and payment of an online commercial transaction between a purchaser and a merchant including verification of an identity of the purchaser and verification of an ability of the purchaser to pay for the transaction, where the identity provider and the payment provider are often different network entities. Other embodiments also provide for protocols, computing systems, and other mechanisms that allow for identity and payment authentication using a mobile module, which establishes single or multilevel security over an untrusted network (e.g., the Internet).  Still other embodiments also provide for a three-way secure communication between a merchant, consumer, and payment provider such that sensitive account information is opaque to the merchant, yet the merchant is sufficiently confident of the consumer's ability to pay for requested purchases. In yet another embodiment, electronic billing information is used for authorization, auditing, payment federation, and other purposes.
Patent CA-2602832-A1 (CA)
Title: Low-concentration capsaicin patch and methods for treating neuropathic pain
Inventor: BLEY KEITH R
IPC: A61K31/165
Filed: 2006-03-30
Abstract: Described here are patches and methods for treating neuropathic pain. In some variations, the neuropathic pain-relieving patch comprises capsaicin or a capsaicin analog, wherein the concentration of the capsaicin or capsaicin analog is less than 1% by weight, and a penetration enhancer, wherein the patch is capable of relieving neuropathic pain over a sustained period of time. The penetration enhancer may be any suitable penetration enhancer. The patches may also include oils, viscosity increasing agents, and the like. In some variations, the pain-relieving patches comprise capsaicin, or an, wherein the concentration of the capsaicin or analog is less than 1%, and a penetration enhancer, whereby delivery of capsaicin from the patch continues for at least an hour, and whereby a single use of the patch provides a therapeutic benefit for at least one month, two months, or three months.  Methods for treating neuropathic pain are also described.
Patent CA-2604680-A1 (CA)
Title: Uplink signaling for global decoder control
Inventor: GAMMIE KEITH B
IPC: H04N7/167
Filed: 2006-04-14
Abstract: Uplink signaling for controlling a plurality of decoders at a remote site. An uplink has a control server for controlling a storage system of the decoders at the remote site. The control server of the uplink controls the storage system by injecting at least one global control stream multiplexed with a transport stream. The transport multiplexed with the global control stream is formed at the uplink for controlling the decoders simultaneously.
Patent CA-2605008-A1 (CA)
Title: Urea derivatives, methods for their manufacture, and uses therefor
Inventor: JARY HELENE
IPC: C07D417/12
Filed: 2006-04-24
Abstract: The present invention provides compounds of formula (I): in which R1, R'1, R2, R'2, R3, Y and G have the meanings given in the description, to a process for their preparation, their application by way of medicaments, and to pharmaceutical compositions containing them.
Patent CA-2605078-A1 (CA)
Title: Plant-derived elastin binding protein ligands and methods of using the same
Inventor: JIMENEZ FELIPE
IPC: A61K38/39
Filed: 2006-04-17
Abstract: The present invention describes novel plant derived elastin-like peptides and peptidomimetics that may serve as functional ligands for elastin receptors and stimulate elastogenesis. The novel plant derived peptides provide an alternative (non-animal derived) source of GXXPG (SEQ ID NO. 2) containing peptides. The present invention also describes therapeutic compositions containing novel plant derived peptides or peptidomimetics useful in stimulating elastogenensis and capillary dilatation. The therapeutic compositions of the present invention that comprise novel plant derived peptides or peptidomimetics may be combined with other therapeutic agents.
Patent CA-2606290-A1 (CA)
Title: Orthese compressive de contention du membre inferieur en forme d'article tricote de type bas, chaussette ou collant
Inventor: CROS FRANCOIS
IPC: A61F13/08
Filed: 2006-04-28
Abstract: L'orthèse comporte une partie de jambe et une partie de pied. La partie de jambe (10), qui s'étend vers le haut à partir de la cheville, applique sur la jambe une pression de contention thérapeutique une fois l'orthèse enfilée. La partie de pied (12), qui s'étend à partir des malléoles (14) jusqu'aux orteils (16) en couvrant le cou de pied (18), est une partie conformée qui enveloppe élastiquement le pied. Le dimensionnement et la structure de maille de la partie de pied sont tels que l'on ait, une fois l'orthèse enfilée : (i) 0 < Px < Pm < Pb et (ii) Pm < 36 mmHg, Px étant la pression appliquée au niveau du cou de pied, Pm étant la pression appliquée au niveau des malléoles, et Pb étant la pression de contention thérapeutique appliquée au niveau de la cheville. De préférence Px = 5 mmHg ~ 25 %, et Pm = 0,5.(Pb + Px) ~ 25 % .
Patent CA-2610432-A1 (CA)
Inventor: COPELAND RICHARD L
IPC: G08B13/24
Filed: 2006-06-02
Abstract: Disclosed are a system and method to detect RFID tags in electronic article surveillance systems using frequency mixing. The system includes an RFID module that includes an energy coupler to receive transmitted energy that includes a first signal at a first frequency and a second signal at a second frequency, and a mixing element to mix the first and second signals, to generate a third signal at a third frequency, and the energ coupler to transmit the third signal to an EAS detection system. Other embodiments are described and claimed.
Patent CA-2610801-A1 (CA)
Inventor: WARSZAUER YEHIEL
IPC: H04N5/235
Filed: 2006-05-31
Abstract: There is provided a light-sensitive system responsive to light supplied by the system and less responsive to other light. The system includes a light source operable to supply time-modulated illumination, and a light sensor having greater response to the time-modulated illumination than to light from sources not so modulated. The invention may be embodied as a camera sensitive to supplied light and relatively insensitive to ambient light, and is useful in providing images for automated image interpretation. A method for photographing an object is also provided.
Patent CA-2612417-A1 (CA)
Inventor: SAH DINAH WEN-YEE
IPC: C07K14/00
Filed: 2006-06-16
Abstract: Antibodies and antibody fragments that bind to the receptor GFRalpha3 and inhibit formation of a Neublastin-GFRalpha3-Ret ternary complex are disclosed.  Also disclosed are methods of using the antibodies and antibody fragments to inhibit phosphorylation of Ret in a cell and treat disorders and in a subject.
Patent CA-2615619-A1 (CA)
Inventor: CORRIGAN THOMAS R J
IPC: B29C33/30
Filed: 2006-07-18
Abstract: Methods of aligning flexible molds, segmented mold and frame apparatus, as well as methods of making microstructured articles (e.g. PDP back panels) are described.
Patent CA-2616028-A1 (CA)
Title: Synthesis of scabronines and analogues thereof
Inventor: DANISHEFSKY SAMUEL J
IPC: A61K31/137
Filed: 2006-07-21
Abstract: A novel synthesis of scabronines, which are related to a broader class of angularly fused tricyclic diterpenoids known as cyathanes, is provided.  Scabronine G, its methyl ester derivative, and other analogs have been shown to have neurotrophic activity. Therefore, these compounds are particularly useful in treating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's diseases, etc. The invention provides for the synthesis of scabronines as well as analogs thereof. Pharmaceutical compositions and method of using the inventive compounds are also provided.