baber/WOPTO huggingface dataset:
Patent AU-579665-B2 (AU)
Title: 2-pyridine-thiol derivatives
Inventor: EZER ELEMER
IPC: C07D213/70
Filed: 1985-10-04
Granted: 1988-12-01
Abstract: The invention relates to new 2-pyridine-thiol derivatives of the formula (I),    <IMAGE>  (I)  wherein R is hydrogen or alkyl having from 1 to 4 carbon atoms, Z is phenyl optionally substituted by one or more halogen atoms and/or alkyl groups having from 1 to 4 carbon atoms, R1 and R2 each independently represents hydrogen, alkyl having from 1 to 4 carbon atoms, alkylphenyl having from 1 to 4 carbon atoms in the alkyl moiety or an   <IMAGE>   group, in which R has the same meaning as defined above, and the substituent   <IMAGE>   is attached to the pyridine ring in the position 3 or 4, with the proviso that if R1 and R2 are both methyl and Z is 4-chlorophenyl, R is other than hydrogen, and acid addition salts thereof. The invention further relates to processes for the preparation of the above compounds and to pharmaceutical compositions containing them as active ingredient. The compounds are pharmaceutically active, in particular show cytoprotective activity.
Patent AU-575225-B2 (AU)
Title: Lavatory cleansing blocks
Inventor: BARFORD ERIC DENNIS
IPC: C11D3/02
Filed: 1985-11-29
Granted: 1988-07-21
Abstract: A lavatory cleaning block is formed of a mixture comprising:(a) from 5 to 85% by weight of one or more anionic surface active agents;(b) from 2 to 50% by weight of one or more solubility control agents having a solubility in water less than that of the anionic surface active agent(s); and(c) from 0.5 to 50% by weight of one or more water-soluble salts of polyvalent metals;
Patent AU-715821-B2 (AU)
Title: Contact lens transfer device
Inventor: EDWARDS RUSSELL JAMES
IPC: B65B25/00
Filed: 1996-04-23
Granted: 2000-02-10
Abstract: The present invention, which relates to the transfer of contact lenses in post hydration processing of the lenses. A lens transfer and insertion assembly (210) removes contact lenses from lens hydration pallets (200), alters their spatial distribution, and deposits them into packaging elements (10). The lenses are transferred with fluid and retained on the transfer assembly by surface tension. <IMAGE>
Patent AU-524777-B2 (AU)
Title: Isolation of tissue protein ppg.
Inventor: BOHN HANS
IPC: G01N33/48
Filed: 1979-09-26
Granted: 1982-09-30
Abstract: A new soluble tissue protein (PP8) and a process for isolating it from human organs is described. The protein has antigenic properties. In the case of diseases which involve tissue disintegration its presence in the blood in increased concentration can be established.
Patent AU-663635-B2 (AU)
Title: Telecommunications system with active database
Inventor: PENZIAS ARNO ALLAN
IPC: H04Q3/00
Filed: 1993-12-24
Granted: 1995-10-12
Abstract: Interexchange carriers make their rate information for long-distance service available in a database 16. PBXs (40) and telephone central offices (31) access that rate information using ISDN and/or SS7 signaling and use it as a basis for determining which carrier to use at any given time in the routing of a call. Such accessing may be carried out on a call-by-call basis. Or a carrier's schedule of rates can be stored locally in the PBX or local switching office, thereby obviating the need for a database query for every call. <IMAGE>
Patent AU-716486-B2 (AU)
Title: Methods for treating respiratory disease
Inventor: MCMICHAEL JOHN
IPC: A61K31/00
Filed: 1996-03-20
Granted: 2000-02-24
Abstract: Methods for treating respiratory disease, including cystic fibrosis, emphysema, bronchitis, and sinusitis are presented. Methods comprise administering to a patient an effective amount of DNA in a manner so as not to be effect gene transfer and expression.
Patent AU-526539-B2 (AU)
Title: 2-(3,4-disubstituted-phenylimino)-imidazolidines
Inventor: STAHLE HELMUT
IPC: C07D233/50
Filed: 1979-12-17
Granted: 1983-01-20
Abstract: 1. Claims for the contracting states : BE, CH, DE, FR, GB, IT, LU, NL, SE 3,4-Disubstituted 2-phenylimino-imidazolidines of general formula (I)  see diagramm : EP0012822,P5,F1  wherein Z represents a radical selected from the group comprising 3-fluoro-4-methylphenyl, 4-fluoro-3-methylphenyl, 4-fluoro-3-nitrophenyl, 4-fluoro-3-chlorophenyl and 4-fluoro-3-aminophenyl, and the acid addition salts thereof. 1. Claims for the contracting state : AT Process for the preparation of 3,4-disubstituted 2-phenylimino-imidazolidines of general formula (I)  see diagramm : EP0012822,P6,F1  wherein Z represents a radical selected from the group comprising 3-fluoro-4-methylphenyl, 4-fluoro-3-methylphenyl, 4-fluoro-3-nitrophenyl, 4-fluoro-3-chlorophenyl and 4-fluoro-3-aminophenyl, and the acid additions salts thereof, characterised in that a) a compound of the formula (II)  see diagramm : EP0012822,P6,F3  wherein Z is as hereinbefore defined and X and Y, which may be the same or different, represent a chlorine atom, an alkylthio group with 1 to 4 carbon atoms or an amino or ammonium group, is reacted with ethylenediamine or an acid addition salt thereof ; or b) the aliphatic acyl group is hydrolytically split off from a 1-acyl-2-phenylamino-imidazoline of general formula (III)  see diagramm : EP0012822,P6,F5  wherein Z is as hereinbefore defined and R represents an aliphatic acyl group ; or c) in order to prepare 2-(4-fluoro-3-aminophenylimino)-imidazolidine, 2-(4-fluoro-3-nitrophenylimino)-imidazoline is hydrogenated and, if desired, the compound thus obtained is converted into a physiologically acceptable acid addition salt.
Patent AU-680843-B2 (AU)
Title: TNF-alpha ribozymes and degradation resistant mRNA derivatives linked to TNF-alpha ribozymes
Inventor: SIOUD MOULDY
IPC: A61K31/70
Filed: 1993-11-03
Granted: 1997-08-14
Abstract: This invention describes compounds active against TNF- alpha  mRNA. It further describes mRNA molecules capable of conferring stability to RNA in vivo. Possible mRNA molecules to be stabilized include ribozymes, antisense molecules and mRNA encoding polypeptides useful for protein production. The ribozymes and antisense molecules described herein are useful in mammals and plants, particularly suited for viral diseases. Methods of production and methods of use are also described.
Patent AU-630190-B2 (AU)
Title: Package for transporting and storing bulk goods
Inventor: BOOTS GERARDUS ANTHONIUS MARIA
IPC: B65D25/18
Filed: 1990-05-28
Granted: 1992-10-22
Abstract: The invention concerns a package for transporting and storing bulk goods, said package comprising an outer package (11) and an inner package (12). The inner package (12) comprises an outer frame (13) and an inner frame (14) which are at least partly attached to each other. The perimeter of the outer frame (13) of the inner package (12) is greater than or equal to the perimeter of the inner frame of the outer package (11), and the perimeter of the inner frame (14) of the inner package (12) is smaller than or equal to the perimeter of the outer frame of the outer package (11). The internal pressure (P1) prevailing in the package (10) is received as tension force (F2) acting on the circumference of the outer package (11), said tension force producing a resultant force (F3) acting from the corners of the outer package (11) on the package (11), said resultant force (F3) reducing the tensions prevailing in the inner package (12) so that the juncture points (19) of the inner frame (14) and the outer frame (13) of the inner package (12) are substantially free of stresses.
Patent AU-775482-B2 (AU)
Title: A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
Inventor: CASTALDI GRAZIANO
IPC: C07C69/90
Filed: 2000-06-21
Granted: 2004-08-05
Abstract: A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives of formula (I) wherein R1 is the OCOR3 group characterized in that it comprises the following steps: a) reaction of a halide of a salicylic acid derivative with hydroxybenzylacohol in the presence of a base: b) nutration of the obtained product in anhydrous conditions by a mixture of nitric acid with a different inorganic acid, or an organic acid, or an anhydride of one or two organic acids: c) recovery of the final product.
Patent AU-599032-B2 (AU)
Title: Cultivation of morchella
Inventor: OWER RONALD DEAN
IPC: A01G1/04
Filed: 1986-04-28
Granted: 1990-07-12
Abstract: The invention pertains to culturing ascocarps or fruitbodies of species of the genus Morchella. Mycelia are provided nutrients and subsequently produce sclerotia. Sclerotia store sufficient nutrient to supply the ascocarps that are developed later. The mycelia and attendant sclerotia are established in a nutrient poor substratum. The fungus is induced to give rise to ascocarp development by initially maintaining the fungus in an environment that is poor in exogenous nutrients, and by exposing the fungus to a high level of water. After induction, primordia appear. The period from primordia appearance until midway to maturation of the fruitbodies represents a critical period during which the fruitbodies are prone to abort. During this critical period, particular attention is directed to maintaining favorable conditions. The fruitbodies, which may be grown to maturation, are harvested.
Patent AU-624261-B2 (AU)
Title: Novel 4,4-disubstituted piperidine derivatives, pharmaceutical compositions containing them and process for preparing the same
Inventor: TOTH EDIT
IPC: C07D211/74
Filed: 1990-08-09
Granted: 1992-06-04
Abstract: The invention relates to compounds of formula (I), <CHEM>  wherein  R<1> represents hydrogen or -CONHR , wherein R represents hydrogen or alkyl, cycloalkyl, or carbocyclic aryl or carbocyclic aryl-alkyl optionally substituted on the aromatic ring by one or more halogen atoms, alkyl or alkoxy ;  R<2> represents ethynyl or acetyl ; Ph<1> and Ph<2>, which may be the same or different, each represents phenyl unsubstituted or substituted by one or more halogen atoms, alkyl, alkoxy, or trihalomethyl or hydroxy optionally esterified by an alkanoic acid; and  n is 1 or 2, and optical isomers and mixtures thereof and all acid addition and quaternary ammonium salts thereof, to pharmaceutical compositions containing these compounds and processes for their preparation. the compounds of formula (I) appear useful for the treatment of psychotic disorders, insomnia, mania, agitation, depression, anxiety, emesis, pain and dementia.
Patent AU-722214-B2 (AU)
Title: Nucleosides with anti-hepatitis B virus activity
Inventor: SCHINAZI RAYMOND F
IPC: A61P1/16
Filed: 1996-06-07
Granted: 2000-07-27
Abstract: A method for the treatment of a host, and in particular, a human, infected with HB V is provided that includes administering an HBV-treatment amount of the stabilized nucleotide of a nucleoside which exhibits anti-hepatitis B activity.
Patent AU-729437-B2 (AU)
Title: Cefadroxil monohydrate tablet formulation
Inventor: REMON JEAN PAUL LOUIS AUGUSTE
IPC: A61P31/04
Filed: 1998-03-19
Granted: 2001-02-01
Abstract: This invention relates to uncoated direct compression tablets containing cefadroxil monohydrate as the active ingredient, which are capable of oral administration to human beings by swallowing, chewing or disintegrating in water resulting in a drinkable dispersion.
Patent AU-676313-B2 (AU)
Title: Method for neutralizing waste
Inventor: SORVIK ARVID INGE
IPC: B09B3/00
Filed: 1994-03-25
Granted: 1997-03-06
Abstract: PCT No. PCT/NO94/00068 Sec. 371 Date Dec. 28, 1995 Sec. 102(e) Date Dec. 28, 1995 PCT Filed Mar. 25, 1994 PCT Pub. No. WO94/23856 PCT Pub. Date Oct. 27, 1994Method for neutralizing waste, such as powder from luminescent tubes and similarly, residue from incineration of household waste, optionally comprising environmentally hazardous components, such as Hg, Cd, Zn, Co or Ba. The waste is fed into a melting furnace in conjunction with an SiO2-rich material, and a reducing agent, and in a first optional step, the furnace is operated at reducing conditions and at a temperature effecting reduction of heavy metals and any other compounds in the raw material, whereby the reduced heavy metal and other components are withdrawn from the furnace with the exhaust gas and are separated from the same, and in a second step the furnace is operated at oxidizing conditions and at a temperature ensuring oxidation of remaining elements in the slag present in the furnace from said first step, whereby the slag becomes, at least gradually, of low viscosity, and the molten slag is drained from the furnace and solidified, optionally die casted and/or water granulated, thus forming inert glassified slag.
Patent AU-681328-B2 (AU)
Title: Improved wax-free chewing gum base
Inventor: SYNOSKY STEVEN
IPC: A23G4/08
Filed: 1996-10-10
Granted: 1997-08-21
Abstract: A chewing gum base is provided which is free of wax as well as a method for producing same. In an embodiment, a wax-free gum base is provided having flavor release characteristics at least as good as similar bases including wax comprising an elastomer, polyvinyl acetate, an elastomer plasticizer, and a sufficient amount of oil to achieve flavor release characteristics that are at least as good as a similar gum base including wax.
Patent AU-730892-B2 (AU)
Title: Aqueous crosslinkable coating compositions
Inventor: OVERBEEK GERARDUS CORNELIS
IPC: C08G18/62
Filed: 1998-03-30
Granted: 2001-03-15
Abstract: An aqueous crosslinkable coating composition suitable for the provision of thick coatings without incurring carbon dioxide bubble formation comprising:(A) an aqueous dispersion of at least one hydroxyl- and acid-functional vinyl polymer having a hydroxyl value of 8 to 250 mg KOH/g of polymer and an acid value of 2 to 55 mg KOH/g of polymer, where the contribution of at least 30% of the acid value results from a monocarboxylic acid(s) of formula:where R1 is H or lower alkyl of 1 to 5 carbon atoms and Q is a spacer group of formula:where X is -O- or -NH-, m is at least 1, preferably 2 or 3, and k is at least 1, preferably 2, 3, 4 or 5; and(B) at least one organic polyisocyanate. The acid of formula (1) preferably comprises beta-carboxyethyl acrylate.
Patent AU-729957-B2 (AU)
Title: Composition comprising at least sodium bicarbonate, its process of preparation and its uses
Inventor: FOURCOT FABRICE
IPC: C01D7/00
Filed: 1996-10-31
Granted: 2001-02-15
Abstract: A new composition comprises sodium bicarbonate, sodium carbonate and ammonia in the form of ammonium salts. Also claimed is the process for its preparation and its uses. The composition contains at least 70% (more preferably 80% and especially 80 - 95%) of sodium bicarbonate, less than 30% (more preferably less than 20% and especially 5 - 15%) of sodium carbonate, and less than 1% ammonia, as NH4+, (more preferably 0.2 - 0.7%). The preferred composition also contains less than 0.1% of ammonium carbamate (more preferably 0.01 - 0.06%) and less than 10% water(more preferably 1 - 6%). The product is used in the form of a fine powder.
Patent AU-780751-B2 (AU)
Title: Process to prepare androst-4-en-17-carboxylic acid cross-reference to related applications
Inventor: GREGA KEVIN C
IPC: C07J75/00
Filed: 2000-10-02
Granted: 2005-04-14
Abstract: The process of the present invention transforms a steroidal ketone of formula (III)to androst-4-en-17beta-carboxylic acid (IV)by reaction with K2SO5.KHSO4.K2SO4.
Patent AU-606619-B2 (AU)
Title: Core-shell polymers and compositions containing core-shell polymers
Inventor: BERZINIS ALBIN PETER
IPC: C08F279/00
Filed: 1987-10-20
Granted: 1991-02-14
Abstract: A core/shell polymer comprises a rubbery core of crosslinked, conjugated diolefin polymer or copolymer with 0 or upto 50%, based on the total core weight, of a first vinyl monomer copolymerized with the diolefin, and one or more polymer shells, at least one of which shells is a vinylaromatic polymer or copolymer, the particles further having an average particle diameter no more than 250 nanometers and toluene swell index of from 13 to 45, preferably from 15 to 25. The core/shell polymers are useful for modifying the properties of olefinic, aromatic addition and/or condensation resins, particularly poly(styrene).
Patent AU-646681-B2 (AU)
Title: Process for preparing an aroma product containing alpha-acetolactic acid
Inventor: VERHUE WALTER MAURITS M
IPC: A23L27/24
Filed: 1991-08-12
Granted: 1994-03-03
Abstract: A process is provided for preparing an aroma product containing a high concentration of  alpha -acetolactic acid, a precursor of the flavour component diacetyl, by subjecting at least one food product constituent to lactic acid bacteria which are in their stationary growth phase, particularly to a cell-free extract or cell lysate of lactic acid bacteria. The food product constituent can be citric acid, lactic acid and especially pyruvic acid or mixtures thereof. The pyruvic acid can be obtained by culturing a bacterium of the genus Propionibacterium, e.g. Propionibacterium freudenreichii. Suitable lactic acid bacteria include Lactococcus lactis, particularly subspecies lactis and its biovar diacetilactis, and Leuconostoc cremoris. The aroma product can be used for flavouring foodstuffs, for example by mixing it with pre-dried food materials.
Patent AU-737065-B2 (AU)
Title: Use of growth hormone in compositions for treating insulin resistance in the heart and for enhancing protein kinase B (PKB) activity
Inventor: OLIN THOMAS
IPC: A61P9/04
Filed: 1998-06-26
Granted: 2001-08-09
Abstract: The present invention relates to a therapy involving administration of human growth hormone for improving cellular function in the heart challenged by insulin resistance and thereby treating or protecting the heart from complications derivable from this condition.
Patent AU-739510-B2 (AU)
Title: Levobupivacaine and its use
Inventor: MATHER LAWRENCE E
IPC: A61K31/435
Filed: 1998-07-21
Granted: 2001-10-11
Abstract: A method of anesthetizing a human patient prior to major surgery, which comprises the administration to the patient of at least 200 mg levobupivacaine.
Patent AU-652959-B2 (AU)
Title: Producing monoclonal antibodies against human T-cell receptor elements using recombinant DNA vectors
Inventor: CHOI YONGWON
IPC: C07K14/72
Filed: 1991-08-08
Granted: 1994-09-15
Abstract: Recombinant DNA vectors which express chimeric T cell receptors are disclosed. These chimeric T cell receptors contain one human element, and the rest of the elements are all of the same, non-human animal species, such as a mouse. Of particular interest are chimeras where the human element is V alpha  or V beta . The vectors are used to transfect cells which derive from the same non-human animal species as the non-human animal species of the chimera, and the resulting transfectants are used to produce monoclonal antibodies against the human element of the chimera.
Patent AU-634423-B2 (AU)
Title: Hydroxymethyl (methylenecyclopentyl) purines and pyrimidines
IPC: A61P31/12
Filed: 1991-10-04
Granted: 1993-02-18
Abstract: Antiviral activity is exhibited by compounds having the formula <CHEM> and its pharmaceutically acceptable salts. v
Patent AU-649295-B2 (AU)
Title: A plug-in module as a component of a toy building block system
Inventor: LARWS PETER
IPC: A63H33/08
Filed: 1991-12-24
Granted: 1994-05-19
Abstract: A construction module is described, one side of which has four slightly resilient spring leaves (6, 6') which are arranged in a tulip shape and can easily snap onto the other five side faces (2 to 5) of an identical construction module. The side faces have strips (8, 8') which can be continuous or interrupted. On the inside, the spring leaves are provided with corresponding connecting elements (7, 7', 7'') which engage behind the said strips. A connection is produced between two construction modules firstly by slight deflection of the spring leaves from their position of rest and by subsequent engagement behind the said strips. The construction modules have the advantage that they can be connected to one another or detached from one another easily and reliably even after a long time and frequent use. <IMAGE>
Patent AU-748706-B2 (AU)
Title: Repressed trans-activator system for characterization of protein-protein interactions
Inventor: SADOWSKI IVAN
IPC: C12Q1/68
Filed: 1998-09-08
Granted: 2002-06-13
Abstract: The invention provides a system for assaying protein-protein interactions. Amino acid sequences of interest are inserted into 'bait' and 'prey' fusion proteins. The bait fusion proteins include a DNA-binding domain. The prey fusion proteins include a transcriptional repression domain. The interaction of the bait and prey fusion proteins is detected by the repression of reporter genes. The reporter genes have operator sequences to which the DNA-binding domain of the bait fusion protein can bind. The reporter genes are expressed unless the prey fusion protein interacts with a bait fusion protein at the operator region of the reporter gene. When a prey fusion protein binds to a bait fusion protein, the expression of the reporter gene is repressed. Compounds that interfere with the interaction of bait and prey fusion proteins may be detected by their ability to reverse the repression of the reporter genes.
Patent AU-747831-B2 (AU)
Title: DNA virus vectors and methods for their preparation
Inventor: DELECLUSE HENRI-JACQUES
IPC: C12R1/92
Filed: 1998-11-05
Granted: 2002-05-23
Abstract: Preparation of DNA virus vectors (I) which can replicate in both eukaryotic and prokaryotic cells from a DNA virus genome (II) of at least 100 kb. (II) is introduced into a eukaryotic target cell to produce a cell with (II) present at least in extrachromosomal form. A DNA segment (III) is introduced into the cell and includes at least the information required for replication of (II) in prokaryotes and at least one marker gene selectable in prokaryotes, flanked by homologous sequences of (II) sufficiently long to permit recombination. (III) is integrated into (II) by recombination, then optionally, cells are selected for presence of an extrachromosomal viral DNA genome. The recombinant genome is purified and isolated. Independent claims are also included for the following: (1) (I) produced this way; and (2) eukaryotic and prokaryotic cells containing (I).
Patent AU-737725-B2 (AU)
Title: Rail vehicle with a fiber composite material head module
Inventor: WAGNER URSULA
IPC: B61D17/06
Filed: 1998-06-12
Granted: 2001-08-30
Abstract: The subject matter of the invention is a rail vehicle with a head module made of a composite fiber material. For this, a joining region with height-tolerance compensating means (5) is arranged on the underframe (3) and a joining edge with longitudinal and lateral tolerance compensating means (7 and 8) is arranged on the wagon body module (2). The head module has joining edges that point toward the wagon body module (2) and the underframe (3) and is provided with reinforced sections (18, 19) that are integrated into the fiber composite material. The head module is attached to the underframe (3) and at least at the head module side walls (14) of the wagon body module (2) by means of fastening means (20, 21), which build up a pre-tensioning force, in such a way that shear-resistant connections are created. As a result, it is possible to control size deviations resulting from the production methods in order to avoid undefined internal stresses during the joining, to absorb without damage the differing heat expansions of a head module of fiber composite material and a wagon body module, as well as to produce the head modules of a fiber composite material and the connections of said modules to the wagon body module (2) and the underframe (3) so as to be not only self-supporting but also load-sharing and easy to repair.
Patent BG-60412-B2 (BG)
Title: New benzazepine derivatives, methods for their preparation and their application as medicaments
Inventor: REIFFEN MANFRED
IPC: C07D223/16
Filed: 1994-01-25
Abstract: The invention relates to benzazepine derivatives having the formula (formula) to methods for their preparation and to medicaments containing them. The compounds have such pharmacological properties which make them suitable for the treatment of sinus tachicardias of different genesis and for the prophylaxy and therapy of the cardiac ischaemic disease.