baber/WOPTO huggingface dataset:
Patent TW-226365-B (TW)
IPC: C07C309/73
Filed: 1992-09-23
Granted: 1994-07-11
Abstract: A novel multi-step process for preparing the (4S &cir& _-enantiomer of 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone in a highly-optically pure form is disclosed. The process involves (1) first esterifying 4-(3,4-dichlorophenyl)-4-ketobutanoic acid with isopropylene or isobutylene to form the corresponding isopropyl or t &cir& _e &cir& _r &cir& _t &cir& _.-butyl 4-(3,4-dichlorophenyl)-4-ketobutanoate; (2) then reducing the ketobutanoic acid ester obtained in the first step with an asymmetric carbonyl reducing agent to form the corresponding chiral isopropyl or t &cir& _e &cir& _r &cir& _t &cir& _.-butyl 4-(3,4-dichlorophenyl)-(4R &cir& _)-hydroxybutanoate; (3) then sulfonylating the (4R &cir& _)-hydroxybutanoic acid ester with methanesulfonyl, benzenesulfonyl or p &cir& _-toluenesulfonyl chloride or bromide in the presence of a standard base to yield the corresponding isopropyl or t &cir& _e &cir& _r &cir& _t &cir& _.-butyl 4-(3,4-dichlorophenyl)-(4R &cir& _)-sulfonyloxybutanoate; (4) next subjecting the 4-sulfonyloxybutanoic acid ester obtained in the third step to a copper-coupling reaction with dilithium diphenyl(cyano)cuprate of the formula  PHI 2Cu(CN)Li2 to effect a stereochemical displacement of the organic (4R &cir& _)-sulfonyloxy group of the (4R &cir& _)-sulfonyloxybutanoic acid ester by the phenyl group of the dilithium diphenylcuprate reagent and so selectively form the corresponding isopropyl or t &cir& _e &cir& _r &cir& _t &cir& _.-butyl 4-(3,4-dichlorophenyl)-(4R &cir& _)-phenylbutanoate, and (5) thereafter cyclizing the stereospecific (4R &cir& _)-phenylated n-butanoic acid ester in the presence of a protic or Lewis acid catalyst to finally yield the desired (4S &cir& _)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone compound in a highly-optically pure form. The latter compound, which is a novel (4S &cir& _)-enantiomer per se, has utility as an intermediate that ultimately leads to pure c &cir& _i &cir& _s &cir& _-(1S &cir& _)(4S &cir& _)N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine (sertraline), which is a known antidepressant agent. The aforementioned isopropyl and t &cir& _e &cir& _r &cir& _t &cir& _.-butyl esters of 4-(3,4-dichlorophenyl)-(4R &cir& _)-hydroxybutanoic acid, as well as their corresponding (4R &cir& _)-methanesulfonyl, (4R &cir& _)-benzenesulfonyl and (4R &cir& _)-p &cir& _-toluenesulfonyl derivatives, are also novel compounds, as are the aforementioned isopropyl and t &cir& _e &cir& _r &cir& _t &cir& _.-butyl esters of 4-(3,4-dichlorophenyl)-(4R &cir& _)-phenylbutanoic acid as well as the aforesaid acid per se. These novel chiral compounds are all useful as key intermediates in the overall process of the present invention.
Patent TW-238307-B (TW)
Title: Novel fruo pyrazole compounds
Inventor: GUO SHENG-JUH
IPC: C07D491/052
Filed: 1993-03-20
Granted: 1995-01-11
Abstract: A compound with formula (I) and its salts, (see claim 1) in which R1 is (see claim 1) R2, R3, R4 is H, X, NO2, CH3, C1~C4 alkyl, OCH3, and n is an integer of 1~4, X is a halogen.
Patent TW-240222-B (TW)
IPC: C07D401/14
Filed: 1993-03-22
Granted: 1995-02-11
Abstract: Compounds of formula (I) : <CHEM> [wherein: R<1> is a cyclic amino group, or a dialkylamino group; R<2> is a group of formula -NHCHR<3>R<4>, wherein R<3> and R<4> are each alkyl, aryl or aralkyl, or together form a cycloalkyl group, or R<2> is an aromatic heterocyclic group, or a group of formula -B-S(O)m-R<5>, wherein R<5> is a substituted alkyl group, or an aromatic heterocyclic group; B is an alkylene or alkylidene group; m is 0, 1 or 2; A is a group of formula -CH=CH- or -(CH2)n-, where n is 1, 2 or 3]; and salts thereof have valuable anti-ulcer activity.
Patent TW-254876-B (TW)
Title: Production process for fixation of sieve wire and sieve screen
Inventor: CHERN JAW-HER
IPC: B23P11/02
Filed: 1993-11-06
Granted: 1995-08-21
Abstract: A production process for fixation of sieve wires and sieve screen, which comprises the following steps: (1) processing of sieve screen sheet: stitching several scoop channels with pre-specified width on the sieve screen sheet; (2) processing of sieve wires: selecting sieve wires with pre-specified length in which the bottom width of sieve wires is slightly wider than width of scoop channel on the sieve screen sheet; (3) heat-treating the sieve screen sheet: heating the sieve screen sheet to a pre-specified temperature; (4) inserting the sieve wires: inserting the sieve wires into the sieve screen sheet; (5) natural cooling: putting the working object at normal temperature for natural cooling; (6) rolling processing: rolling the cooled working object into a cylindrical shape to complete the fixation of sieve wires and sieve screen.
Patent TW-419484-B (TW)
Title: Amphoteric porous particulate comprising a basic polysaccharide and a polymer of an organic acid or a salt thereof, process for producing the same, deodorant composition of a chitosan particulate and a deodorant composition of a polysiloxane
Inventor: HASEBE YOSHIHIRO
IPC: C08B37/08
Filed: 1995-03-20
Granted: 2001-01-21
Abstract: An amphoteric porous particulate comprising a basic polysaccharide and a polymer of an organic acid containing a reactive vinyl group or a salt thereof and having an average particle size of 50 mu m or less, which is capable of adsorbing a large amount of an acid or a base that is stronger than the acid or basic groups thereof and which is useful as a deodorant, a cosmetic or the like. The amphoteric porous particulate is obtained by emulsifying or suspending an aqueous solution containing a basic polysaccharide and an organic acid having a reactive vinyl group in a hydrophobic solvent and thereafter effecting polymerization thereof. A deodorant comprising a chitosan particulate having an average particle size of 0.01 to 50 mu m as a deodorant. A chitosan particulate having an available amino group content of 1.0 x 10<-7> to 1.0 x 10<-2> mol/g and a specific surface area of 10 to 300 m<2>/g is particularly useful. A polysiloxane having long-chain alky1 groups and a melting point of 20 DEG C or above is useful as an oil component of a deodorant.
Patent TW-458954-B (TW)
Title: Anthracycline derivatives for use in the treatment of amyloidosis, process for producing them and pharmaceutical composition comprising them
Inventor: SUARATO ANTONINO
IPC: A61P25/00
Filed: 1995-08-16
Granted: 2001-10-11
Abstract: The present invention provides the use in the manufacture of a medicament for use in the treatment of amyloidosis of an anthracycline of formula A: wherein R1, R2, R3 and X are appropriate substituents. Novel compounds of the formula A, processes for their production and pharmaceutical compositions containing them are also described.
Patent TW-273502-B (TW)
IPC: A23F3/20
Filed: 1995-07-28
Granted: 1996-04-01
Abstract: In prepn. of instant black tea, soln. in cold water: (a) the black tea leaves are extracted with water at 60-130 degrees C; (b) the tea leaves are sepd.; (c) this first extract is conc. to 5-12% solids, and cooled to 5-15 degrees C, to form an insol. cream, which is sepd. from the first conc. extract; (d) the cream is mixed with the spent black tea leaves or with green tea leaves; (e) the mixt. is extracted with water at above 70 degrees C, to give a second extract, which is sepd. from the spent tea leaves; (f) the first and second extracts are mixed; and (g) the mixt. is conc. to the required solids content and dried.
Patent TW-296522-B (TW)
IPC: H04N7/10
Filed: 1995-11-03
Granted: 1997-01-21
Abstract: The present invention provides a system for serving information, comprising:   one or more storage medium units having a plurality of storage media;   a plurality of end devices connected to the storage medium unit, each of which has input means and display means, wherein the end devices output demand data requesting the selecting information data; and control means for controlling the storage medium unit according to requests from the plurality of end devices, said control means having first control means (SMM) and second control means (SMG), wherein the first control means have a table for memorizing status and/or characteristics of each of the storage media, wherein the second control means output the request for assignment of the storage medium to the first control means on basis of the condition of the end devices and wherein said first control means propose a suitable storage medium to the second control means for the information serving to the end devices according to data memorized in the table and the request from the control means.   <IMAGE>
Patent TW-283784-B (TW)
Title: Process for eliminating dislocations in the neck of a silicon single crystal
Inventor: SAPASIVAM CHANDRASEKHAR
IPC: C30B15/00
Filed: 1995-11-23
Granted: 1996-08-21
Abstract: A silicon single crystal prepared by the Czochralski method including a neck having an upper portion, an intermediate portion, and a lower portion. The upper portion contains dislocations. The intermediate portion is between the upper and lower portions. A majority of the intermediate and lower portions has a diameter greater than 10 millimeters, and the lower portion is free of dislocations. The crystal also includes an outwardly flaring segment adjacent the lower portion of the neck, and a body adjacent the outwardly flaring segment.
Patent TW-346402-B (TW)
Title: Racket frame and process for producing the same
Inventor: TAKECHI KENJIRO
IPC: A63B102/04
Filed: 1996-04-10
Granted: 1998-12-01
Abstract: A racket frame comprising a frame main body, a fiber reinforced plastic, an ionomer film covering the frame main body, and a coating film formed over the ionomer film; the frame main body comprising a fiber reinforced plastic; the racket frame comprising a gas permeable porous material film interposed between the ionomer film and the coating film.
Patent TW-403751-B (TW)
Title: Novel crystal form of anhydrous 7-([1<alpha>, 5<alpha>,6<alpha>,]-6-amino-3-azabicyclo[3.1.0.]hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt
Inventor: HANDANYAN LYNNE A
IPC: A61K31/495
Filed: 1996-05-13
Granted: 2000-09-01
Abstract: The anhydrate of 7-([1<alpha>, 5<alpha>, 6<alpha>]-6-amino-3-azabicyclo[3.1.0.]hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt has advantageous stability for formulation as an antibacterial agent.
Patent TW-377371-B (TW)
Title: Method of reducing yellowing of water-borne road marking paints and composition used therein
Inventor: JILEK JOSEF HANS
IPC: C09D7/45
Filed: 1996-07-24
Granted: 1999-12-21
Abstract: A water-borne road marking paint composition which includes a chelating agent capable of chelating iron ions to form a substantially colorless complex is provided. A road marking produced from the traffic paint of the present invention substantially reduces of prevents yellowing of white road marking from iron and iron compound debris strewn on the road surfaces. A method of reducing or preventing yellowing of a newly-applied road marking on a road surface of a water-borne road marking paint is also disclosed. The method comprises incorporating in the water-borne road marking paint a chelating agent capable of chelating iron ions to form a substantially colorless complex. Further reduction of yellowing of the road marking is observed when a pigment dispersant is incorporated in the water-borne road marking paint.
Patent TW-426515-B (TW)
Title: Pharmaceutical composition tor use in inhibiting plasminogen activator inhibitor 1
Inventor: BERG DAVID THOMPSON
IPC: A61K31/38
Filed: 1996-10-09
Granted: 2001-03-21
Abstract: A pharmaceutical composition for use in inhibiting plasminogen activator inhibitor 1, comprising a compound having the formula, wherein R1 and R3 are independently hydrogen, -CH3, formula, wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Patent TW-343196-B (TW)
Title: Process for the preparation of 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilides
Inventor: BERND GALLENKAMP
IPC: C07D231/16
Filed: 1996-11-26
Granted: 1998-10-21
Abstract: A process for the preparation of 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilides of the formula (formula 1) in which Ar represents optionally substituted phenyl, which is characterized in that: (a) in a first stage, 1,3-dimethyl-5-chloro-pyrazole-4-carbonyl chloride of the following formula (II) is reacted with alkali metal fluorides, if appropriate in the presence of a polar aprotic organic solvent, (formula II) and (b) in a second stage, the 1,3-dimethyl-5-fluoro-pyrazole-4-carbonyl fluoride of the formula (III) obtained in this reaction is reacted with anilines of the formula (IV) (formula III) H2N-Ar (IV) in which Ar has the abovementioned meaning, if appropriate in the presence of an acid acceptor and if appropriate in the presence of an inert organic solvent.
Patent TW-357060-B (TW)
Title: Sea urchin feed
Inventor: LAWRENCE ADDISON L
IPC: A23K1/18
Filed: 1996-12-09
Granted: 1999-05-01
Abstract: A sort of semi-moist, stable sea urchin feed, including extruded solid pellets or bodies sunk in sea water, having 12-24 wt.% of rough protein, 30-60 wt.% of rough carbohydrate and 12-40 wt.% of water, having the feed bodies an as manufactured water activity of up to about 0.8 and, self-sustaining in sea water for a period of at least about 24 hours.
Patent TW-363148-B (TW)
Title: Process unit
Inventor: HAZAMA HIROYUKI
IPC: G03G15/08
Filed: 1997-02-26
Granted: 1999-07-01
Abstract: A process unit including a drum unit having a photoconductor drum, a developing device having a development housing accommodating a developer, and a developing roller disposed in the development housing, and a support shaft supporting the developing device so as to be pivotable relative to the drum unit is provided. The process unit detachably mounted in a printer includes a spring interposed between the developing device and the drum unit to impart to the developing device a turning moment about the support shaft so that the developing roller is urged toward the photoconductor drum. The developing device has an input gear for transmitting a drive force to the developing roller, while the printer has an output gear for driving the input gear. The direction of the drive pressure angle of the output gear to the input gear, or a direction opposite to this direction is headed for the support shaft.
Patent TW-377298-B (TW)
Title: Dilator capable of introducing separating stresses in outer wall tissues of a section of human anatomy
Inventor: JOHNSON BRUCE C
IPC: A61F13/02
Filed: 1997-04-23
Granted: 1999-12-21
Abstract: A nasal dilator that prevents the outer wall tissue of the nasal passages of the nose from drawing in during breathing comprises a truss member. The truss member includes a flexible strip of material having a first end region, a second end region and an intermediate segment. The first and second end regions are adapted to engage the outer wall tissue of first and second nasal passages of the nose. The intermediate segment is configured to traverse a portion of a nose located between the first and second nasal passages, and a pad can be provided to prevent adhesion of the intermediate segment to the nose. The truss member further includes first and second resilient banks secured to the strip of material adjacent opposite edges of the intermediate segment. The resiliency of the first and second resilient banks acts to stabilize the outer wall tissue and thereby prevents the outer wall tissue of the first and second nasal passages from drawing in during breathing. Rather than a pad preventing adhesion, an adhesion reduction can be provided by a partial adhesion arrangement.
Patent TW-402650-B (TW)
Title: Washing and drying machine
Inventor: YOSHIDA YOSHIO
IPC: D06F25/00
Filed: 1997-08-08
Granted: 2000-08-21
Abstract: A kind of washing-drying machine which can send the warm air to the washing/drying tank and alternatively rotate the rotating wing and washing/drying tank for drying the washing to achieve the high quality of washing without having crinkles. During the untying and drying process (step S200), turn the rotating wing 19 to right and left; then, during the rotating and drying process (step 201), rotate the washing/drying tank 15 according to the output of the rotating speed detector 26; and, in the drying degree determination process (step S202), judge the drying degree of the drying object 18 from the output of the temperature detector 25.
Patent TW-413992-B (TW)
Title: Mainframe device and information processing device
Inventor: NAMIKAWA HIROFUMI
IPC: G06F9/445
Filed: 1997-08-20
Granted: 2000-12-01
Abstract: This invention is about mainframe device for information processing use for fax machine device or personal computer, and connected the external device to mainframe to form information processing device. It is easily and precisely rewriting the memory content used for program within mainframe device or external device connected with mainframe. The fax machine device F is connected with plural external device Gn (n = 1, 2, 3iK) by daisy link way. Installing 1st flash memory 2 and 2nd flash memory 22 for memory controlling program use in fax machine device F and external device Gn. Installing socket 12 on fax machine device F, mounted ROM 13 of memory controlling program on socket 12. The controlling program inside the ROM 13 is transferred to the 1st flash memory 2 of fax machine device F and the 2nd flash memory 22 of each external device Gn.
Patent TW-345667-B (TW)
Title: High thermal conductivity composite magnetic substance
Inventor: YOSHIDA EKICHI
IPC: H04B15/02
Filed: 1997-09-09
Granted: 1998-11-21
Abstract: A high thermal conductivity composite magnetic substance formed by dispersing a soft magnetic power into the organic binder, which is characterized in that the organic binder is further dispersed with a thermal conductive powder.
Patent TW-339290-B (TW)
Title: System and method for slitting a continuous metal band into a plurality of stripe bands
Inventor: SHIMAKATA AKIO
IPC: B21D1/05
Filed: 1997-09-25
Granted: 1998-09-01
Abstract: A system for slitting a continuous metal band into a plurality of stripe bands, including: - an uncoiler element placed at one end of the transportation path for uncoiling of the continuous metal bands toward te other end of the transportation path; - a cutting element located on the transportation path for slitting the continuous metal band into a plurality of stripes; a recoliner located on the other end of the transportation path for individual recoling of each stripe, including a plurality of non-fixed independent pieces being each of which adjusted of the pulling force.
Patent TW-346438-B (TW)
Title: Method for producing resin article having undercut shape
Inventor: OMINE SYOZO
IPC: B29C51/08
Filed: 1997-11-17
Granted: 1998-12-01
Abstract: A method for producing resin article having an undercut shape, which comprises the following steps: forming a parison as an intermediate molded article by injection molding a thermoplastic resin; expanding the parison in open molds prior to blow molding of the parison in the final shape; closing the molds; and blow molding the parison in the closed molds to form the final shape of the article.
Patent TW-403963-B (TW)
Title: The manufacture method of cobalt silicide
Inventor: HUANG SHIN-YUAN
IPC: H01L21/285
Filed: 1997-12-24
Granted: 2000-09-01
Abstract: A manufacture method of cobalt silicide comprises the following steps: provide a silicon substrate, form the titanium layer to cover the silicon substrate. Then the silicon layer is formed to cover the titanium layer. Next, form the cobalt layer to cover the silicon layer; and use the thermal process to make the cobalt layer react with the silicon atom to form the cobalt silicide layer.
Patent TW-347442-B (TW)
Title: Scroll hydraulic machine
Inventor: KAWADA MINORU
IPC: F04C18/02
Filed: 1998-01-22
Granted: 1998-12-11
Abstract: A scroll hydraulic machine comprising: a fixed scroll; a swirling scroll performing a revolutionary swirling motion while engaging with the fixed scroll; and a balance weight in which a distance between a center of revolution of the swirling scroll and the center of gravity of the balance weight being changed in response to rotational speed of the swirling scroll.
Patent TW-555558-B (TW)
Title: Freeze-dried composition containing glycosphingolipid and process for producing the same
Inventor: MARUYAMA KAZUTOSHI
IPC: A61K47/28
Filed: 1998-02-05
Granted: 2003-10-01
Abstract: An object of the invention is to improve the solubility of a glycosphingolipid by preparing a freeze-dried composition and a manufacture method thereof; the freeze-dried composition comprises an alpha-glycosylceramide represented by general formula (A) or a salt thereof, a polyoxysorbitan/aliphatic anhydride ester, and a disaccharide or monosaccharide and preferably further contains deoxycholic acid or histidine. On said formula, R1 is H or OH; X is an integer of 7 to 25; R2 is -CH2(CH2)YCH3, -CH(OH)(CH2)YCH3, -CH(OH)(CH2)YCH(CH3)2, -CH=CH(CH2)YCH3, or -CH(OH)(CH2)YCH(CH3)CH2CH3 (where Y is an integer of 5 to 17); one of R3 and R4 is H and the other is H, OH, NH2, or NHCOCH3; one of R5 and R6 is H and the other is OH; one of R7 and R8 is H and the other is OH; and R9 is H, CH3, or CH2OH.
Patent TW-380326-B (TW)
Title: Gas insulation bus
Inventor: OZAWA ATSUSHI
IPC: H01G4/08
Filed: 1998-04-08
Granted: 2000-01-21
Abstract: The invention relates to a kind of gas insulation bus which provides a flange capacitor with large capacitance for to suppress surge. The invention is composed of the flange capacitor which employs insulation film as the dielectric with plasticity and forms conductive layers on both sides of the dielectric. The large capacitor employing insulation film with ten-thousands pF could provide the surge suppression effect as the flange capacitor.
Patent TW-374269-B (TW)
Title: Battery life extending technique for mobile wireless applications
Inventor: SHARP STEVEN J
IPC: H04B1/40
Filed: 1998-06-25
Granted: 1999-11-11
Abstract: An operating Voltage applied to transmitter's power amplifier in a mobile wireless transceiver is dynamically controlled so as to improve the efficiency of the transmitter at all output power levels. In one embodiment, the bias current levels within the transmitter are also varied to optimize the efficiency of the transmitter at all output power levels. In a preferred embodiment, a highly efficient switching regulator is controlled by a control circuit to adjust the operating voltage an/or bias current for the power amplifier in the transmitter. The control circuit has as its input any of a variety of signals which reflect the actual output power of the transmitter, the desired output power, or the output voltage swing of the transmitter.
Patent TW-464653-B (TW)
Title: B-ring estratriene diols
Inventor: KAGAN MICHAEL Z
IPC: A61P19/10
Filed: 1998-04-28
Granted: 2001-11-21
Abstract: This invention provides estrogenic agents having the formula wherein A is formula; B is formula; R is SO3<SP>-</SP>X<SP>+</SP>; X<SP>+</SP> is alkali metal, alkaline earth metal, or ammonium.