baber/WOPTO huggingface dataset:
Patent CA-2878291-A1 (CA)
Inventor: PAMER ERIC
IPC: C12Q1/68
Filed: 2013-07-03
Abstract: A method and an apparatus are provided for determining T-cell repertoire recovery after allo-HSCT or identifying patients at high risk of infection. Combination of 5'-RACE PCR with deep sequencing was used to quantify TCR diversity in 33 individuals using a single oligonucleotide pair. Analysis of duplicate blood samples revealed highly reproducible detection of expanded TCR clonotypes. After 6 months, recipients of cord blood grafts without anti-thymocyte globulin therapy approximated the TCR diversity of healthy subjects, whereas recipients of T-cell-depleted peripheral blood stem cell grafts had a 28-fold and 14-fold lower CD4+ and CD8+ T-cell diversity, respectively. After 12 months, these differences had leveled out for the CD4+, but not the CD8+ T-cell compartment.
Patent CA-2878507-A1 (CA)
Title: Procede et systeme permettant de mesurer une propriete d'un fluide non newtonien
Inventor: NEWMAN JOHN W
IPC: G01N33/42
Filed: 2013-07-08
Abstract: La présente invention concerne un système et un procédé permettant de mesurer la déformation au cours du temps de la surface d'un fluide non newtonien dans un récipient d'échantillonnage, en réponse à un jet d'air qui est appliqué pendant une durée spécifiée. La modification du déplacement de la surface est mesurée de manière quantitative par triangulation optique ou au moyen d'un autre dispositif optique ou électronique similaire permettant de mesurer une distance. Après l'arrêt du jet d'air, l'attraction gravitationnelle amène l'échantillon à retrouver son profil de surface d'origine. L'amplitude du déplacement de la déformation dû à la force du jet d'air et la récupération du déplacement, pendant des périodes spécifiques de temps, sont caractéristiques d'un matériau liant bitumineux contenant diverses quantités de polymères ou d'autres additifs utilisés pour contrôler les propriétés finales et la performance du matériau. Par conséquent, la comparaison des mesures quantitatives d'échantillons témoins peut permettre d'effectuer une discrimination par rapport à des échantillons ayant des propriétés différentes et donc différentes formulations.
Patent CA-2883171-A1 (CA)
Inventor: SCARAMUCCI JOHN P
IPC: F16K1/42
Filed: 2015-02-26
Abstract: A seat assembly for a valve includes an annular seat carrier with an annular sealant groove formed along an inner side. The seat carrier has at least one sealant injection port extending there through from an outer side and intersecting the sealant groove for injecting a sealant into the sealant groove. A sealant distribution member extends along the sealant groove to cooperate with the seat carrier to define an annular sealant flow path along the inner side of the seat carrier. The sealant distribution member has a plurality of openings formed there through to provide a plurality of fluid flow passageways from the sealant groove for injecting the sealant between the seat carrier and the valve member.
Patent CA-2884195-A1 (CA)
Inventor: NEUMANN DIETMAR
IPC: E04H15/60
Filed: 2013-09-04
Abstract: A retractable enclosure is comprised of at least two displaceable structural bow frames which each define a roof section and opposed upwardly extending side sections. These sections are interconnected by joint connectors. The sections are also formed of extruded profiled straight metal tubes which have extruded interconnection channels. The tarp sections of flexible material are engaged by channels of some of the bow frames and collapse and expand as the bow frames are displaced closer or away from one another. Access to the enclosure can be provided from all sides thereof for access to its interior.
Patent CA-2889015-A1 (CA)
Inventor: TRONSMO ARNE
IPC: A01N63/10
Filed: 2013-10-22
Abstract: The present invention provides a composition comprising (i) chitosan or chitopoly- or chitooligo-saccharides thereof, wherein said chitosan or chitopoly- or chitooligo- saccharides thereof comprise ß-(1-4)-linked D-glucosamine and N-acetyl-D- glucosamine monomers and have a degree of acetyiation between 0.05 and 0.20 and an average degree of polymerization = 250 (molecular weight = 42,000 Da), and (ii) a fungicide not containing chitopoly- or chitooligo-saccharides.
Patent CA-2890108-A1 (CA)
Inventor: RONINSON IGOR
IPC: A61K31/5377
Filed: 2013-11-01
Abstract: The invention provides a method for treating prostate cancer in a subject comprising administering to the subject an effective amount of a selective inhibitor of one or more of CDK8 and CDK19. In some embodiments the inhibitor inhibits CDK19. In some embodiments, the inhibitor inhibits CDK8 at a Kd of lower than 200 nM and/or inhibits CDK19 at a Kd of lower than 100 nM. In some embodiments, the prostate cancer is androgen independent. In some embodiments, the prostate cancer is androgen independent due to one or more of androgen receptor gene amplification, androgen receptor gene mutation, ligand-independent transactivation of androgen receptor and activation of intracellular androgen synthesis. In some embodiments, the inhibitor inhibits increased activity of NF-??. In some embodiments, the inhibitor does not inhibit increased basal levels of NF-??. In some embodiments, inhibition of one or more genes by AR is not inhibited.
Patent CA-2892654-A1 (CA)
Title: Dispositif de commande pour un moteur
Inventor: TANTOT NICOLAS JEROME JEAN
IPC: B64C11/30
Filed: 2013-11-15
Abstract: L'invention consiste en un dispositif de commande pour un moteur, comprenant des moyens de calcul (150) d'une consigne d'angle de calage (160) d'au moins une hélice du moteur, les moyens de calcul (150) utilisant un modèle de performance de l'hélice prenant en compte au moins une vitesse de vol (115) pour adapter une consigne d'angle de calage en prenant en compte une consigne de puissance sur arbre.
Patent CA-2894165-A1 (CA)
Inventor: ANG WOON TIONG
IPC: B60B30/10
Filed: 2015-06-12
Abstract: A wheel lift comprises a frame having ground engaging elements, a four bar linkage structure supported by the frame, lifting arms extending from the four bar linkage and for receiving and supporting a wheel and a handle for operating the four bar linkage to raise and lower the wheel. The frame defines an open space for receiving a wheel, for example a vehicle wheel. The lifting arms may be raised and lowered and locked in position to aid in removing and/or mounting vehicle wheels.
Patent CA-2895224-A1 (CA)
Inventor: SCHMIDT KLAUS MICHAEL
IPC: A61M16/00
Filed: 2013-12-23
Abstract: An anesthetic circuit is provided for treating a patient. The anesthetic circuit includes a membrane having a plurality of hollow fibers. Also provided is a fluid separation apparatus connectable to an anesthetic circuit. In a further embodiment, a method is provided for anesthetic treatment of a patient.
Patent CA-2895330-A1 (CA)
Inventor: RAJENDRAN SARAVANAMOORTHY
IPC: C07K16/00
Filed: 2013-12-18
Abstract: Provided are methods of using ion exchange based chromatography to control the levels of high mannose glycoforms in a glycoprotein sample, such as an antibody sample. The high mannose glycoforms can be removed from the sample or isolated and enriched. Also provided is a composition comprising a glycoprotein, such as an antibody, from which the high mannose glycoforms have been reduced or removed or isolated or enriched using an ion exchange based chromatography step.
Patent CA-2897295-A1 (CA)
Inventor: KEILHAUER STEVE
IPC: A47C3/18
Filed: 2015-07-15
Abstract: On an article of furniture, a bearing assembly is disposed between an elongate central structure and a seat, which permits rotation between the seat and the base. A  tablet is provided, which is connected to a tablet arm with a first cylindrical member, and the tablet arm is connected to the elongate central structure of the base with a second cylindrical member. The second cylindrical member is disposed around the elongate central structure with a flange at the upper end thereof. The bottom of the seat has a lobed friction bushing disposed such that the flange of the second cylindrical member contacts the lobed friction bushing and frictionally resists rotation of the tablet arm as the seat rotates 360 degrees relative to the base, leading the tablet to follow the seat as it rotates. A lobed friction bushing is also provided.
Patent CA-2898228-A1 (CA)
Inventor: FRICKMANN JESPER
IPC: C12P19/00
Filed: 2014-02-21
Abstract: La présente invention concerne des procédés de saccharification d'un matériau cellulosique comprenant l'étape consistant à soumettre le matériau cellulosique à une composition d'enzyme cellulolytique et de polypeptide GH61, et éventuellement une catalase, en présence d'oxygène dissous à une concentration dans la plage de 0,5 à 10 % du niveau de saturation. L'invention concerne également des procédés de production des produits de fermentation souhaités, tels que l'éthanol, à l'aide d'un procédé comprenant une étape de saccharification selon l'invention.
Patent CA-2901360-A1 (CA)
Inventor: REYNOLDS DAVID A
IPC: B09C1/06
Filed: 2014-03-06
Abstract: There is provided a method for achieving oxidation of organic contaminants held in low permeability soil and its contained pore water. The method comprises the supply and electromigration of an oxidant throughout the soil and pore water by means of an applied direct current via electrodes arrayed within the soil, followed by the heating of the soil by an applied alternating current using the identical electrodes.
Patent CA-2902238-A1 (CA)
Inventor: STAUNTON DOUGLAS ALAN
IPC: A61B17/16
Filed: 2014-03-15
Abstract: An end effector of a surgical robotic manipulator includes a removeable cutting accessory. The cutting accessory includes a cutting tip and a shaft extending along an axis. A drive member is configured to rotatably drive the shaft of the cutting accessory. An actuator is coupled to the drive member for rotatably driving the drive member. A clutch assembly is supported by and is selectively rotatable relative to the drive member and receives the shaft of the cutting accessory along the axis of the shaft for selectively locking the shaft to the drive member.
Patent CA-2905024-A1 (CA)
Title: Systems and methods for establishing cloud-based instances with independent permissions
Inventor: VON EICKEN THORSTEN
IPC: G06F15/16
Filed: 2014-03-12
Abstract: A method and system for facilitating management of cloud-based service instances, the system comprising one or more computing systems configured to communicate with at least one multi-tenant computing cloud, and configured to establish a cloud-based service instance hosted in the multi-tenant computing cloud and an access entity with permissions to access the established cloud service instance. The system can receive a request for the cloud-based service instance, the request authenticated as originating from a requestor; consult a set of access controls associated with the cloud-based service instance; determine, responsive to the consulting, if the request is allowable by the requestor; and enable, responsive to determining that the request is allowable by the requestor, the requestor to complete the request using a restricted access credential associated with the access entity.
Patent CA-2905782-A1 (CA)
Inventor: LYONS MARTIN S
IPC: A63F13/30
Filed: 2014-03-11
Abstract: Various embodiments directed to systems and methods that enable cross platform persistent gaming sessions using a mobile device in a mobile device-enhanced system are disclosed herein. In one embodiment, a method may include enabling a cross platform gaming session in a system that includes a gaming machine that presents a game, and a computing device distinct from the gaming machine, both in communication with one another. The method may include associating the computing device with the gaming machine. The computing device may have one or more displays. The method may include receiving, by the computing device, reformatted graphical data from the gaming machine. The method may include presenting the game on the one or more displays of the computing device using the reformatted graphical data.
Patent CA-2906277-A1 (CA)
Inventor: GUINEY PATRICK
IPC: A61N1/39
Filed: 2014-03-14
Abstract: A device (200) which includes a monitoring unit(210), a therapy unit(220), and a display (100)that includes a touch screen(110). The monitoring unit (210) can be configured to monitor a person's vital signs, such as a person's electrocardiogram (ECG). The therapy unit (220) can be configured to administer an electric shock. The display(100)can be configured to display the ECG and enable a user to scroll the displayed ECG back and forth and/or to zoom in and zoom out the displayed ECG by touching the touch screen(110). The display (100)can also be configured to enable the user to select two or more separate segments of the ECG to view together at the same time on the display(100), which segments can be separated by intervening segments of the ECG that can be hidden from being viewed on the display (100). The display(100)can have multiple user-interface windows(120, 130).One window (120)can be configured to only display functions related to the monitor unit(210) and/or the therapy unit(220), while another window (130) can be configured to display software applications, including an electronic patient care record (ePCR) application.
Patent CA-2907799-A1 (CA)
Inventor: SCHAFFER DAVID V
IPC: A61K35/761
Filed: 2014-05-29
Abstract: La présente invention concerne des virions infectieux de virus adéno-associés recombinés (VAAr) comprenant un variant de protéine capsidique et un acide nucléique hétérologue. La présente invention concerne, en outre, les variants de protéines capsidiques d'un virus adéno-associé (VAA) (et/ou un acide nucléique codant pour lesdits variants de protéines capsidiques du VAA), qui confèrent à un virion infectieux du VAAr une résistance accrue contre les anticorps neutralisants humains dirigés contre le VAA. La présente invention concerne, en outre, des cellules hôtes contenant un virion infectieux du VAAr et/ou un acide nucléique codant pour un variant de protéine capsidique du VAA faisant l'objet de l'invention. La présente invention concerne, également, des méthodes d'administration d'un acide nucléique hétérologue en direction d'une cellule cible, ladite cellule cible étant mise en contact avec un virion infectieux du VAAr faisant l'objet de l'invention. La présente invention concerne, par ailleurs, des méthodes d'administration d'un produit génique chez un individu, lesdites méthodes impliquant généralement l'administration d'une quantité efficace d'un virion du VAAr faisant l'objet de l'invention à un individu en ayant besoin.
Patent CA-2908093-A1 (CA)
Title: Retrofit reinforcing structure addition and method for wind turbine concrete gravity spread foundations and the like
Inventor: HENDERSON ALLAN P
IPC: E02D27/42
Filed: 2015-10-02
Abstract: A retrofit reinforcing structure addition and method for an existing gravity spread foundation for a wind turbine or the like having a central pedestal and a spread section is provided. The retrofit structure addition includes a collar formed around the pedestal of the spread foundation. The collar is formed by a shape sustaining member, such as a CMP, placed around the pedestal to define an annular ring between the CMP and the pedestal that is filled with cementitious material. Radial bolts extend horizontally through the collar and into the side of the pedestal. Soil and/or rock anchor bolts extend vertically through the collar, the spread portion of the foundation and into the underlying soil and/or rock substrate. The radial and anchor bolts are post-tensioned to ensure that the cementitious material of the collar remains in compression and the bolts are always in static tension, strengthening the original gravity spread foundation and extending the fatigue life thereof.
Patent CA-2909570-A1 (CA)
Inventor: THISSEN ROGIER LOUIS JACQUES WILLEM
IPC: H04N21/442
Filed: 2014-04-15
Abstract: First apparatuses (1)to be remotely controlled by devices (3) comprise interfaces (11) for receiving first signals from second apparatuses (2) that define that the second apparatuses (2) have received codes from the devices (3), interfaces (12) for sending second signals to the devices (3), and first controllers (21) for detecting the first signals and in response to detection results generating the second signals for providing assistance to the configurations of the devices (3) forremotely controlling the second apparatuses (2). The devices (3) for remotely controlling the first apparatuses (1) comprise interfaces (14) for sending codes to the second apparatuses (2) for remotely controlling the second apparatuses (2), interfaces (15) for receiving the second signals from the first apparatuses (1), and second controllers (22) for detecting the second signals for configuring the devices (3) for remotely controlling the second apparatuses (2).
Patent CA-2911006-A1 (CA)
Inventor: ADAMS ROGER R
IPC: A63B17/02
Filed: 2011-07-15
Abstract: A wearable device configured to selectively provide roller transportation, including a shoe, a plurality of wheel assemblies, each wheel assembly being configured to selectively roll relative to a ground surface about an associated axis of rotation, and a frame connected between the wheel assemblies, the frame comprising a trunk and a plurality of branches extending from the trunk, each of the branches being configured for connection to at least one of the plurality of wheel assemblies, wherein at least a portion of the shoe is located vertically higher than at least a portion of the frame when at least one of the wheel assemblies is in contact with the ground surface and the at least one of the wheel assemblies is positioned to selectively roll relative to the ground surface.
Patent CA-2911087-A1 (CA)
Title: Novel cloning, expression & purification method for the preparation of ranibizumab
Inventor: SHANDILYA HARISH
IPC: C12N15/63
Filed: 2014-04-28
Abstract: The present invention relates to Ranibizumab cloning, expression and production using a novel approach for better yield and biologically active protein.
Patent CA-2913588-A1 (CA)
Title: Procede et systeme permettant d'authentifier un utilisateur afin qu'il puisse faire fonctionner un dispositif electrique
Inventor: ADELSON ALEX M
IPC: G06K7/10
Filed: 2014-07-29
Abstract: La présente invention concerne l'authentification d'un utilisateur, afin qu'il puisse faire fonctionner un dispositif électrique dans un réseau, en codant un symbole d'identification avec des données d'identification qui identifient l'utilisateur, et en codant un symbole composite avec les données d'identification et des données d'exploitation qui permettent de faire fonctionner le dispositif électrique. Le symbole composite est associé au dispositif électrique à faire fonctionner. Une image du symbole d'identification et une image du symbole composite sont capturées et comparées. Il est permis à l'utilisateur de faire fonctionner le dispositif électrique lorsque les données d'identification du symbole composite correspondent aux données d'identification du symbole d'identification.
Patent CA-2913839-A1 (CA)
Inventor: ROUSE MARTY
IPC: C08L63/00
Filed: 2015-12-03
Abstract: A method and composition is provided for structural reinforcement using fiber-reinforced polymers. Saturated fiber mesh is prepared in advance and stored in a frozen state, to control the rate at which the epoxy cures. In some embodiments, at least one layer of removable film is used to contain the epoxy within the saturated mesh during storage or transport. Film layers are then removed as required during the application of the saturated mesh to the object or structure to be reinforced. One or more layers can be built up on the structure to form a reinforcing shell of composite material. The invention extends to method of preparing and using the frozen saturated mesh, as well as the frozen saturated mesh itself.
Patent CA-2914182-A1 (CA)
Inventor: GARDNER MARTIN
IPC: B23B25/04
Filed: 2015-12-07
Abstract: A lathe or other rotating machine includes a tool rest on a carriage that is movable along the work piece. The carriage includes a post that is movable with the tool rest. The post supports a guard that is disposed between the user and the work piece.  The guard may include a frame surrounding a transparent portion. The frame may support a plurality of light emitting elements directed onto the work piece. An extendable/retractable transparent portion may be extended from the guard between the user and the work piece.  The extendable/retractable portion and/or the transparent portion may be a magnifier.
Patent CA-2917117-A1 (CA)
Title: Pulley
Inventor: BARNET JULIEN
IPC: B63B21/04
Filed: 2014-07-03
Abstract: The present invention relates to the field of pulleys, and more particularly pulleys for deflecting a rope. According to the invention, the pulley comprises: · a one-piece sheave (11) comprising two opposite longitudinal faces (12, 13), a central transverse cutout (14), and a concave external surface forming an annular groove (15) intended to deflect a rope (16), the central recess (14) and the concave external surface (15) being fixed with respect to one another, · a sling (17) for attaching the sheave (11), passing though the central cutout (14) in the sheave (11), the attachment sling (17) being in direct contact with the central cutout (14), · a spacing element (20) designed to space apart the attachment sling (17) from the longitudinal faces of the sheave (11).
Patent CA-2917280-A1 (CA)
Title: Pilot grouping and route protocols in multi-carrier communication systems
Inventor: BLACK PETER JOHN
IPC: H04W74/04
Filed: 2006-09-22
Abstract: Embodiments disclosed herein relate to methods and systems for pilot grouping, route protocols, and scheduling in multi-carrier communication systems. In an embodiment, an access terminal may group a plurality of pilot signals characterized by different frequencies into one or more pilot groups, each pilot grouping being identified by a plurality of parameters (e.g., a PN offset and a group ID). Each pilot group may include pilot signals having substantially the same coverage area. The access terminal may further select a representative pilot signal from each pilot group for pilot strength reporting. The access terminal may also use the pilot grouping for effective set management.
Patent CA-2917339-A1 (CA)
Title: Diffractor for diffracting sound
Inventor: WIJNANT YSBRAND HANS
IPC: E01B19/00
Filed: 2014-07-07
Abstract: The invention relates to a diffractor for diffracting sound of traffic on a travel surface, the diffractor comprising at least one diffraction plate to be disposed laterally beside the travel surface, wherein the diffraction plate is provided with a pattern of recesses in the upper surface thereof for the purpose of diffracting the traffic noise in a direction which differs from the lateral direction, wherein each of the recesses is divided into individual resonators by intermediate walls provided in the recesses, wherein the recesses have acoustically substantially non-absorbing walls and are free of acoustically absorbing material, and wherein the intermediate walls between adjacent resonators comprise at least one throughflow opening along which the rainwater can flow from the one resonator to the other.
Patent CA-2917682-A1 (CA)
Inventor: VAKALOPOULOS ALEXANDROS
IPC: A61P9/10
Filed: 2014-07-08
Abstract: The invention relates to novel benzyl-1H-pyrazolo[3,4-b]pyridines, to methods for the production thereof, to the use thereof alone or in combination for the treatment and/or prophylaxis of diseases, and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.
Patent CA-2919837-A1 (CA)
Inventor: JORDAN MICHAEL
IPC: A61K31/496
Filed: 2014-08-01
Abstract: Disclosed are combination therapies and related compositions that may contain one or more of a p53 potentiating agent, a DNA-damaging agent, an agent that inhibits cell cycle check point, and a pharmaceutically acceptable carrier. Also disclosed are methods of using such compositions for the treatment of conditions related to T cell and/or B cell activation in subjects in need of such treatment.