baber/WOPTO huggingface dataset:
Patent CZ-289287-B6 (CZ)
Title: Di-clavulanate salt derived from clavulanic acid and diamino ether, process of its preparation and use
Inventor: CALLEWAERT GEORGE LEO
IPC: C07D503/00
Filed: 1995-12-22
Abstract: In the present invention there is disclosed a di-clavulanate salt derived from clavulanic acid of the general formula I and a diamino ether of the general formula II wherein Re1 is an alkylene group containing 1 to 4 carbon atoms and each of Re2 and Re3 is a hydrogen atom or an alkyl group having 1 to 8 carbon atoms, or Ri2 and Ri3 together complete a heterocyclic ring having four to seven carbon atoms. A process for preparing the clavulanic acid salt includes the steps of reacting the clavulanic acid, or salt thereof, with diamino ether in an organic solvent and isolation of the resulting salt. The clavulanic acid salt is used in pharmaceutical formulations along with a pharmaceutically acceptable carrier, solvent or vehicle and optionally a beta lactam antibiotic. At the same time, it can be also used as intermediate for preparing a potassium salt.
Patent CZ-285492-B6 (CZ)
Title: Apparatus for carrying out peritoneal dialysis
Inventor: JEPPSSON JAN BERTIL
IPC: A61M1/00
Filed: 1995-01-30
Abstract: PCT No. PCT/SE95/00086 Sec. 371 Date Sep. 17, 1996 Sec. 102(e) Date Sep. 17, 1996 PCT Filed Jan. 30, 1995 PCT Pub. No. WO95/20985 PCT Pub. Date Aug. 10, 1995Apparatus for carrying out peritoneal dialysis. The apparatus comprises a weighing device (37) provided with a case (50) for forming an airtight space. A heat bag (38) and, optionally, a discharge bag (42) are positioned in the space, said bags being connected with a catheter for the patient, who is to perform peritoneal dialysis. The apparatus comprises a pump arrangement (57) connected with the case (50) for producing overpressure and underpressure, respectively, in the space inside the case. Valve arrangements (39, 44) are adapted to connect either the discharge bag (42) or the heat bag (38) with the patient's catheter. By providing an underpressure in the case (50). fresh dialysis solution is provided to the heat bag (38) from supply bags, whereupon used dialysis fluid is extracted from a patient to the discharge bag (42). By causing an overpressure in the case (50), a fresh and heated dialysis solution is supplied from the heat bag (38) to the patient, whereupon the discharge bag (42) is drained to a waste or to collection bags. The flow of dialysis solution is monitored by the apparatus by means of weighing the case (50) and its contents. Suitable data for the treatment is stored in a memory unit of the apparatus.
Patent SK-280909-B6 (SK)
Title: Process for the production of a seasoning sauce from bread
Inventor: MULLER RUDI
IPC: A23L7/25
Filed: 1993-10-21
Abstract: A process for the production of a seasoning sauce in which an enzyme-containing, fungus-covered substrate comprises divided bread of wheat gluten. The substrate is mashed with salt water, the mash is subjected to a three stage fermentation and then clarified by squeezing pasteuring and filtration.
Patent SK-283968-B6 (SK)
Title: Method and device to draw-in coils into slots of stator laminated cores of electric machines
Inventor: SADIKU SADIK
IPC: H02K15/06
Filed: 1998-01-15
Abstract: The inventive method and device are used to draw-in coils into slots of stator laminated cores of electric machines. In order to improve upon the existing draw-in method, the invention provides that in a first phase of the draw-in process, the draw-in star, the short draw-in lamellae and the long draw-in lamellae move synchronously with their upward free ends from a first starting position through the drilled hole of the stator beyond the upper rim thereof to a second position. In a second phase, the draw-in star and the short draw-in lamellae continue to move together. At the same time, the long draw-in lamellae are drawn back to a third position slightly above the upper rim of the stator. In a third phase, the draw-in star, the short draw-in lamellae and the long draw-in lamellae move back from the third position to the starting position.
Patent SK-278307-B6 (SK)
Title: Track tamping machine
Inventor: THEURER JOSEF
IPC: E01B27/16
Filed: 1992-12-21
Abstract: The tamper with a machine frame (3) placed on the gears together with the casing aggregate being able to change a height of it, is equipped with the lifting off and equalising aggregate (12) having a drive enabling lifting off and equalising together with the further lifting off equipment (20), the optional lifting off equipment (15) is assigned to it, it is equipped with one grabbing device (31) at least, used for grabbing of the rail (23), branching rail (24) with the own lifting off drive (28). The grabbing equipment (31) is located on the target carrying frame (26) and it is possible to pre-set it with the use of the movable drive (30) according to the frame (3) of the machine. The contact part (33) is assigned to the lifting off device (15), in this end range which is joined with the grabbing device (31), it used for placing of the grabbed rail (23) with the use of the grabbing device.
Patent SK-286537-B6 (SK)
Title: Substituted polyethylene polyamines, process of their preparation and using of them
Inventor: KUCERA MILAN
IPC: C10L1/00
Filed: 2004-01-30
Abstract: Disclosed are substituted polyethylene amines having general formula (I), method of their production and using as additives inhibited or limited production of the sediments in the process of splitting hydrocarbon residues, which simultaneously inhibit creation of coke precursors, which are primarily asphaltenes and absorbing free radicals affected primarily product stabilisation during their separation and their storing.
Patent SK-287522-B6 (SK)
Title: Use of inhibitors of IL-18 production and/or action
Inventor: DINARELLO CHARLES
IPC: C07K16/24
Filed: 2000-07-17
Abstract: Use of inhibitors of IL-18 production and/or action for the preparation of medicaments for inhibiting tumour metastasis.
Patent CZ-302224-B6 (CZ)
Title: Voltage regulation system
Inventor: FOGLAR JAROSLAV
IPC: G05B11/01
Filed: 2005-09-13
Abstract: The present invention relates to a voltage regulation system comprising an input transformer, a regulating transformer with a power and control windings, a control unit with information input from an input and/or output voltage of the system, a regulated voltage source, and a switching gear adapted for controlling a voltage applied to the control winding of the regulating transformer. The system includes a switching feedback relay (4) with normally closed contacts (41) and with circuit-closing contacts (42). The input transformer (1) is connected as an autotransformer with a power winding (11) and with a source regulation winding (12) with plurality of taps (121). The regulating transformer (2) has a separated power winding (21) and a feeding regulation winding (22) with an input (220), two taps (222, 223) and an output (223). Both the transformers (1, 2) have their windings on toroidal cores, and the beginning (111) of power winding (11) of the input transformer (1) is connected to a terminal connector (10) of a power input of the whole voltage regulation system, while the end (112) of this power winding (11) is connected to a beginning (211) of the power winding (21) of the regulating transformer (2), and at the same time the end (212) of the power winding (21) of the regulating transformer (2) is connected to a terminal connector (100) of power output of the whole voltage regulation system, and further one of regulation winding (12) taps (121 ) of the input transformer (1) is connected to the second regulation winding (22) tap (222) of the regulating transformer (2), while a regulation winding (22) input (220) of the regulating transformer (2) is connected, over feedback relay (4) normally closed contacts (41 ), to the voltage terminal connector (10) of the whole voltage regulation system power input and the regulation winding (22) output (223) of the regulating transformer (2) is connected to a neutral wire terminal connector (1000), while the regulation winding (22) first tap (221) of the regulating transformer (2) is connected to a regulated output (310) of a regulated voltage source (3), which is connected through the first control coupling (30) to the system control unit (5) and the second control coupling (40) provides a control linkage from the system control unit (5) to the feedback relay (4).
Patent CZ-301861-B6 (CZ)
Title: Bar severing machine with deburring device
Inventor: ZELENKA MIROSLAV
IPC: B23D27/00
Filed: 2007-10-10
Abstract: In the present invention, there is disclosed a bar severing machine with a deburring device consisting of a frame, chucking tongs and cutting disk reaching between the chucking tongs. It further consists of at least one deburring disk (1) the shaft (3) of which, being rotatably mounted in the frame (2), is kinematically coupled via toothed gears (4) with a driving unit (5), wherein the frame (2), being slidably mounted in first linear guides (6) attached to a lower frame (11), is coupled with a feeding mechanism (7). It further consists of at least two chucking tongs (8), from which at least one chucking tongs (8) are slidably mounted in a second linear guide (9), and a feeding mechanism (10) that is attached to both the chucking tongs (8) and the lower frame (11). The bar severing machine with a deburring device of the present invention has two contra-rotating deburring disks (1).
Patent CZ-303116-B6 (CZ)
Title: Process for preparing O-substituted (2R,3R)-3-(3-hydroxyphenyl)-2-methyl-4-pentenoic acids
Inventor: VLASAKOVA RUZENA
IPC: C07C51/353
Filed: 2010-12-30
Abstract: In the present invention, there are disclosed O-substituted (2R, 3R)-3-(3-hydroxyphenyl)-2-methyl-4-pentenoic acids of the general formula I, in which R denotes and alkyl group containing 1 to 4 carbon atoms, or a benzyl group, a 4-methoxybenzyl group, a benzhydryl or trityl group wherein the acids are optically pure, optically enriched, optionally racemic. The compounds of the general formula I are novel and represent important intermediate in tapentadol synthesis. Another aspect of the present invention is a process for preparing O-substituted acids, wherein the preparation process is characterized in that cinnamyl propanoates of the general formula III, in which R is as defined above, are subjected in the stage A to rearrangement using strong bases to form racemic acids of the general formula (+/-)-I and the so prepared racemic acids of the general formula (+/-)-I, in which R is as defined above are subjected in the stage B to optical cleavage using crystallization of the salt of the compound (+/-)-I with a chiral base in suitable solvents being selected from the group consisting of lower alcohols containing 1 to 4 carbon atoms, acetone, methylethyl ketone, diethylether, tert-butylmethylether, ethyl-acetate, dichloromethane and water, or mixtures thereof.
Patent CZ-306789-B6 (CZ)
Title: Connection of a stimulation circuit quality indicator
Inventor: KLINKOVSKÝ TOMÁŠ
IPC: A61N2/02
Filed: 2016-05-05
Abstract: The stimulation circuit quality indicator consists of inverting terminal stage of a stimulator connected to bioburden, where the current sensing resistor (3) is connected to the end stage (1), while, between the current sensing resistor (3) and the bioburden, there is connected the the serial combination of the first resistor (4) and the second resistor (5), whose common point is an output of the indication voltage (U) on the control unit (6) generating an optoacoustic signal on the indicating device (7).
Patent CZ-309844-B6 (CZ)
Inventor: KOSTELANSKÝ FILIP
IPC: C07D219/10
Filed: 2021-09-03
Abstract: Deriváty akridinu, výhodně substituované karboxamidovou skupinou nesoucí skupinu obsahující uhlíkatý řetězec zakončený bazickou funkcí, substituované uhlíkatým řetězcem ve formě alkynylu zakončeným azidoskupinou sloužící ke kovalentní vazbě příkladně na oligonukleotidovou sondu. Modifikace jádra slouží k upevnění vazby na dvoušroubovici DNA pomocí vodíkových vazeb s dusíkem a kyslíkem guaninu, dále pak pomocí vodíkové vazby amidického vodíku přes molekulu vody na fosfátovou skupinu mezi příslušným guanosinem a sousedním nukleosidem. Azidoskupina sloužící k azido-alkynové cykloadici na vhodně modifikovaný řetězec příkladně oligonukleotidu. Použití derivátů akridinu nesoucích azidoskupinou jako meziproduktů pro přípravu interkalátorů DNA.
Patent SK-286357-B6 (SK)
Title: Sustained release pharmaceutical composition and use thereof
Inventor: BENINCOSA LISA
IPC: A61K31/00
Filed: 1999-11-12
Abstract: A sustained release pharmaceutical composition in a unit dosage form and adapted for oral administration comprising 2 to 12 mg of 5-[4-[2-(N-methyl-N-(2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, i. e. rosiglitazone, or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable carrier, which dosage forma provides a plasma concentration of rosiglitazone of at least 50 ng/ml over a period of up to 24 hours. Also disclosed is the use of said pharmaceutical composition in the manufacture of a medicament for the treatment of diabetes mellitus of type 2 and conditions associated with diabetes mellitus.
Patent SK-285641-B6 (SK)
Title: A process for the preparation of {2-[4-(alpha-phenyl-p- chlorobenzyl)piperazin-1-yl]ethoxy}acetic acid and novel intermediates therefor
Inventor: REITER JOZSEF
IPC: C07D241/04
Filed: 2000-11-29
Abstract: It is disclosed a novel process for the preparation of cetirizine of formula (I) as well as {2-[4-( alpha -phenyl-p-chloro-benzyl)piperazin-1-yl]ethoxy}acetamides of formula (II), wherein R1 and R2 represent, independently, a C1-4 alkyl group optionally substituted by a phenyl group, a C2-4 alkenyl group or a cyclohexyl group, or R1 and R2 form together with the adjacent nitrogen atom a morpholino group. According to the described process, an acetamide of formula (II) is hydrolysed, if desired in the presence of a phase transfer catalyst, to obtain cetirizine.
Patent CU-23746-B6 (CU)
Title: Composición farmacéutica y su método de administración subconjuntival y tópica del cisplatino en pacientes con tumores malignos epiteliales y glandulares de la conjuntiva
Inventor: MELGARES RAMOS MARIA DE LOS ANGELES
IPC: A61K9/08
Filed: 2008-12-29
Abstract: La presente invención se relaciona con la oncología y en particular con composiciones farmacéuticas y el método terapéutico para el tratamiento del carcinoma epidermoide de la conjuntiva o (squamous carcinoma). Se logran nuevas composiciones en forma de colirio e inyecciones por vía subconjuntival que comprenden cisplatino, Lidocaína, agua purificada csp, prednisona, benzalconio. El método de tratamiento consiste en Cirugía Exeretica, asociado a varios ciclos de infiltración local de cisplatino y colirio estos neo y adyuvantes a la cirugía, las dosis oscilan entre 1 a 10 mg. El carcinoma epidermoide de la conjuntiva también llamado carcinoma escamoso es el 2do tumor más frecuente del ojo y sus anejos diagnosticándose aproximadamente 34 nuevos casos por ano en Cuba, según Registro Nacional del cáncer; aunque se ha reportado un incremento en los últimos anos de este tumor en el país, su incidencia aunmenta en países tropicales pero se reportan en el mundo cifras de incidencia enmarcadas entre 0.13 a 2.8 casos por 100.0000 habitantes por ano siendo frecuente en hombres como mujeres, sin embargo existen diferencias notables entre ambos sexos. Los adenocarcinomas resultan ser tumores menos frecuentes pero más invasivos y metastisantes por lo que un tratamiento adecuado y rápido mejoraría su sobrevida.
Patent CZ-301900-B6 (CZ)
Title: Concrete mixture reinforced with metal fibers, cement matrix and premixes for preparing such concrete mixture
Inventor: CHEYREZY MARCEL
IPC: C04B111/20
Filed: 1998-11-27
Abstract: In the present invention, there is disclosed a concrete mixture in which metallic fibers are dispersed. The concrete mixture being obtained by mixing with water a composition comprising: a hardened cementitious matrix including (a) cement; (b) aggregate particles having a maximum particle size Dmax of at most 2 mm; (c) pozzolanic-reaction particles having an elementary particle size of at the most 1 micron; (d) constituents capable of improving the toughness of the matrix selected from the group consisting of acicular and flaky particles, wherein the particles have an average size of at most 1 mm and which are present in a proportion by volume of between 2.5 and 35 percent of the combined volume of the aggregate particles (b) and of the pozzolanic-reaction particles (c); and (e) at least one dispersing agent; (f) metal fibers dispersed in the hardened cementitious matrix, wherein (i) the fibers have an individual length 1 of at least 2 mm and an 1/d ratio of at least 20, d being the diameter of the fibers, (ii) the ratio R of the average length L of the fibers to the maximum particle size Dmax of the aggregate particles is at least 10 and (iii) the amount of fibers is such that their volume is less than 4 percent, preferably 3.5 percent of the volume of the concrete after it has set; and (g) water, wherein the percentage by weight of water W with respect to the combined weight of the cement (a) and of the particles (c) is in the range 8 to 24 percent.
Patent CZ-301254-B6 (CZ)
Title: Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation
Inventor: ACHARD DANIEL
IPC: A61P23/00
Filed: 2001-03-01
Abstract: The present invention relates to pharmaceutical compositions containing as an active substance at least one compound of the general formula I, in which Re1 represents the group -N(Re4)Re5, -N(Re4)-CO-Re5, -N(Re4)-SOi2Re6, or same pharmaceutically acceptable salt thereof, novel derivatives of the general formula I, pharmaceutically acceptable salts thereof as well as their preparation.
Patent CZ-300102-B6 (CZ)
Title: Self-inking stamp
Inventor: ZINDL PETER
IPC: B41K1/40
Filed: 2001-04-12
Abstract: A self-inking stamp with overhead inking, with a lower component (1) for positioning on a surface to be stamped, with a swivel mechanism (W) for a print platen support (11) arranged in the lower component (1) for reciprocal swiveling movement between a stamp pad (4) and a support frame (A) and with an actuator upper component (2) movable against the bias of a spring (6) relative to the lower component (1), the actuator upper portion being connected by its lateral parts (2'') to the lower component (1) by a swivel axle of the print platen support (11) extending through elongated openings in narrow sidewalls of the lower component (1), whereby the actuator upper component (2) is connected to the lower component (1) by lateral elastic snap connections and is provided at its lower end with lateral snap recesses (9), which may be engaged by swivel axle stubs (10) of the print platen support (11) inserted into the guide slots (12) of the lower component (1).
Patent CZ-304488-B6 (CZ)
Title: Bleaching composition, ligand and catalyst as well as method of bleaching a substrate
Inventor: BOERZEL HEIDI
IPC: C07D471/08
Filed: 2001-11-15
Abstract: The present invention relates to a bleaching composition comprising: a) a monomer ligand or transition metal catalyst thereof of a ligand having the general formula I; wherein each R is independently hydrogen, F, Cl, Br, hydroxyl, C1-C4-alkylO-, -NH-CO-H, -NH-CO-C1-C4-alkyl, -NH2, -NH-C1-C4-alkyl, and C1-C4-alkyl; R1 and R2 are independently selected from: C1-C4-alkyl, C6-C10-aryl, and, a group containing a heteroatom capable of coordinating to a transition metal, wherein at least one of R1 and R2 is the group containing the heteroatom; R3 and R4 are independently selected from hydrogen, C1-C8 alkyl, C1-C8-alkyl-O-C1-C8-alkyl, C1-C8-alkyl-O-C6-C10-aryl, C6-C10-aryl, C1-C8-hydroxyalkyl, and -(CHi2)inC(O)OR5 wherein R5 is independently selected from: hydrogen, C1-C4-alkyl, n is from 0 to 4, and mixtures thereof; and, X is selected from C=O, -[C(R6)i2]iy- wherein y is from 0 to 3, each R6 is independently selected from hydrogen, hydroxyl, C1-C4-alkoxy, C1-C4-alkyl; and b) the balance carriers and adjunct ingredient. The invention also relates to a ligand and a bleaching catalyst as well as a method of bleaching a substrate being characterized in that the above-described bleaching composition is applied to the substrate in an aqueous medium.
Patent CZ-295990-B6 (CZ)
Title: Self-service payment and information terminal
Inventor: CECH RADOMIL MGR
IPC: G06F13/10
Filed: 2003-07-03
Abstract: The present invention relates to a self-service payment and information terminal, consisting of a processor unit (1) interconnected with an input and positioning device (2), display and positioning unit (3), a communication unit (4) being connected to a telecommunication network (25), a payment unit (5) being connected to a printing unit (8). The terminal further comprises a hybrid card reader (6) and a pin pad (7). Said processor unit (1) is further connected with a telephone unit (15), a scanner (16) and a printer (17). The invention is characterized in that said processor unit (1) is connected to interact with a peripheral device processor unit (10) being connected to interact with a coin feeder (11), a bar code reader (12), a multimedial unit (13) and an auxiliary peripheral device (14). The invented self-service payment and information terminal is intended for use in the field of providing free or paid information, communication and payment services for both institutions and public.
Patent SK-287719-B6 (SK)
Title: Drospirenone for hormone replacement therapy
Inventor: HEIL WOLFGANG
IPC: A61P9/00
Filed: 2001-01-18
Abstract: A pharmaceutical composition comprising as a first active ingredient an estrogen, such as estradiol or estradiol valerate, in sufficient amounts to treat disorders and symptoms associated with deficient endogenous levels of estrogen in women, and as a second active ingredient 6 beta , 7 beta ; 15 beta ; 16 beta -dimethylene-3-oxo-17 alpha -preg-4-ene-21, 17-carbolactone (drospirenone, DRSP) in sufficient amounts to protect the endometrium from the adverse effects of estrogen. The pharmaceutical composition is useful for treating peri-menopausal, menopausal and post-menopausal women, it may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. This combination therapy may comprise continuous, sequential or interrupted administration, or combinations thereof, of DRSP and estrogen, where each of the active ingredients may be optionally administered in micronized form.
Patent SK-286962-B6 (SK)
Title: Device for production plastic hollow articles
Inventor: MESSNER WOLFGANG
IPC: B29C48/25
Filed: 2002-03-21
Abstract: A device (1) for production hollow articles of plastic using the extrusion blow moulding process, having an extrusion unit (2), which is mounted in a housing frame and having at least one blow moulding station (12,13). The extrusion unit (2) comprises an extruder (3) and an extruder head (4) with at least one an extrusion die (41) connected to the extruder (3). The extruder defines the longitudinal direction of the device. The blow moulding station (12, 13) comprises a blow moulding table (14, 15) with at least one mould (16), which is provided with an opening on the side of the mould facing the extrusion die (41). The blow moulding table (14, 15) is movable on a lateral path extending substantially perpendicularly to the longitudinal direction from an end position at the side of the extruder head (4) into a position below the extruder head (4) and back again, in order to bring the extrusion die (41) and the opening of the mould (16) into vertical overlap with one another. The extrusion unit (2) may be mounted in the housing so as to be capable of vertical (W) tilting and lateral swivelling and is displaceable in the longitudinal direction (G).