baber/WOPTO huggingface dataset:
Patent CO-6241098-A2 (CO)
Title: Una composicion de microesferas biodegradables adecuadas para la liberacion controlada de peptido de control de la glucosa y formacion de la misma
Inventor: KWAK HYUN HEE
IPC: A61K9/52
Filed: 2009-11-19
Abstract: Se describen las microesferas biodegradablescapaces de liberar un péptido regulador de la glucosa deuna manera controlada, que comprende un portadorpolimérico biodegradable con el péptido regulador de laglucosa encapsulado en éste, y los métodos para lapreparación de las mismas. Además, para asegurar la altaeficiencia de encapsulamiento y la alta estabilidad delfármaco encapsulado, las microesferas no muestran unefecto inicial rápida ni tampoco liberación incompleta, ypermiten la liberación de orden cero de los fármacos en unperiodo prolongado, mejorando de este modo el efectoterapéutico del fármaco.1.- Una microesfera biodegradable capaz de liberar unpéptido regulador de la glucosa de una manera controlada,caracterizada porque comprende un portador poliméricobiodegradable con el péptido regulador de la glucosaencapsulado en éste.2.- La microesfera biodegradable de conformidad conla reivindicación 1, caracterizada porque el péptidoregulador de la glucosa se selecciona del grupo queconsiste de exendina-3 sintética, exendina-4 sintética, yhomólogos y agonistas de los mismos, sintéticos.3.- La microesfera biodegradable de conformidad conla reivindicación 2, caracterizada porque el péptidoregulador de la glucosa es exendina-4.4.- La microesfera biodegradable de conformidadcon la reivindicación 1, caracterizada porque el polímerobiodegradable se selecciona de un grupo que consiste deácido poli-L-láctico, ácido poli-D-láctico-ácido-co-glicólico,ácido poli-L-láctico-ácido-co-glicólico y ácido poli-D,L-láctico-ácido-co-glicólicc ácido.
Patent CO-6331413-A2 (CO)
Title: Implante intervertebral expansible
Inventor: CAIN CHRISTOPHER
IPC: A61F2/30
Filed: 2010-11-05
Abstract: Se suministra un implante intervertebral expansible para ser insertado dentro de un espacio intervertebral definido por vértebras adyacentes. El implante intervertebral expansible incluye un par de porciones de manguito exteriores y un núcleo interior dispuesto entre las porciones de manguito exteriores. El movimiento del núcleo interior con relación a las porciones de manguito exteriores hace que las porciones de manguito exteriores se desvíen alejándose una de la otra, acoplando así el implante intervertebral expansible con las vértebras y ajustando la altura del espacio intervertebral.
Patent CO-6670580-A2 (CO)
Title: Valsartan altamente cristalino
Inventor: BURGBACHER JENS
IPC: A61K31/41
Filed: 2013-02-01
Abstract: La presente invención se refiere a una forma altamente cristalina de valsartan que tiene una cristalinidad cercana a, o de aproximadamente el 100 por ciento, así como composiciones farmacéuticas de la misma. y un proceso para la preparación de las mismas que comprende las etapas de:(a) combinar valsartan sólido con un solvente que sea un éster,(b) calentar la combinación mencionada hasta una temperatura debajo de la disolución completa del valsartan sólido;(c) agitar la mezcla durante un tiempo efectivo para formar una suspensión, formando los solventes de la misma un licor madre;(d) separar los sólidos en la suspensión, del licor madre; y(e) secar los sólidos mencionados para dar una forma altamente cristalina de valsartan.En donde dicha forma cristalina de Valsartan es efectiva en el tratamiento y/o prevención de la hipertensión arterial y trastornos afines.
Patent DD-142551-A2 (DD)
Title: Verfahren zur herstellung von spinnloesungen aus vinylmonomeren durch substanzpolymeri2ation
Inventor: PIPPEL WINFRIED
IPC: C08F2/02
Filed: 1979-03-28
Abstract: Die Erfindung betrifft ein diskontinuierliches Einstufenverfahren
zur Herstellung von Spinnlösungen aus Vinylraonomeren durch
Substanspolymerisation, Entmonomerisierung der Reaktionsmasse und
deren Auflösung in stark polaren organischen Lösungsmitteln in einer·
Vorrichtung zur heterogenen Substanzpolymerisation nach DD-PS 129 557,
wobei zwischen den einzelnen Teilschritten der Reaktion keine
Reaktionsmassetransportoperationen notwendig sind. Durch die
Kombination mehrerer derartiger Vorrichtungen ist eine
quasikontinuierliche Spinnlösungsherstellung möglich« Der
Gesamtprozeß wird nach einem Programm gesteuert.
Patent EP-1016671-A2 (EP)
Inventor: COTROPIA JOSEPH P
IPC: C12N5/24
Filed: 1991-12-21
Abstract: A method for neutralizing HIV-1 is disclosed. A
preferred embodiment utilizes a novel human monoclonal
antibody that binds to a conserved region of the gp41
transmembrane subunit of the virus. The antibody is
produced by continuous cell lines developed using human B
lymphocyte cells collected from a patient possessing high
titers of anti-HIV antibodies. The conserved region bound
by the neutralizing antibody is a peptide of approximately
12 amino acids in length and preferably 8-10 amino acids.
Similar regions on HIV-2 and SIV are also disclosed. The
present invention is further directed to a kit and a
method for detecting the presence and determining
concentration of an antibody that inhibits HIV-1
 fusion-associated epitope , a peptide on gp41 with the
amino acid sequence represented by  GCSGKLIC . The
detection and quantitation method includes an
enzyme-linked immunosorbent assay (ELISA). The
determination of the concentration of the antibody that
inhibits HIV-1 fusion-associated epitope on gp41, present
in body fluids of a patient seropositive for HIV-1
antibodies, provides the physician with an objective means
to form a prognosis for each individual case and assists
the clinician therefore in determining the appropriateness
to initiate medical intervention or change therapy.
Patent EP-1026305-A2 (EP)
Inventor: JORDING WOLFHARD
IPC: D06F58/26
Filed: 1996-08-20
Abstract: The laundry dryer has a drum, a fan and a gas-heated heater to heat the process air current by means of a burner (5). The gas is blended with prim. air as combustion air before the burner(5), which is a pre-mixing burner without additional supply of sec. air to the burner surface. The burner (5) is preceded a mixing chamber (11) with a gas nozzle (12) that extends into the mixing chamber (11) and with at least one prim. air supply opening (13) with a constant cross-section, and at least one additional prim. air supply opening (13') with an adjustable cross-section.
Patent EP-1045033-A2 (EP)
Inventor: FORT THOMAS L
IPC: C12Q1/689
Filed: 2000-03-09
Abstract: Amplification primers and methods for specific amplification and detection of a Shiga-like
toxin I (SLT-I) target are disclosed. The primer-target binding sequences are useful for
amplification and detection of SLT-I target in a variety of amplification and detection reactions.
Patent EP-1055593-A2 (EP)
Inventor: YAMAOKA HIROSHI
IPC: E05B83/00
Filed: 2000-05-25
Abstract: A U-shaped antitheft device comprises: a U-shaped arm
member 3 having lock recesses 4a formed in two end portions
thereof; a bar member 2 having a pair of insertion holes 8 for
receiving insertion of the two end portions of the arm member
3, a rod hole 9 for slidably receiving push rods (rod members)
20 so that the push rods 30 are engaged/disengaged with/from
the lock recesses 4a of the arm member 3, and a lock hole 10
for receiving and supporting a cylinder lock 13, the respective
holes having axes located in one and the same plane; springs
(urge members) 21 provided in the rod hole 9 for urging the push
rods 20 to retreat; and support members 11 connected to the bar
member 2 (a body 6) in the rod hole 9 for supporting the springs
21. In the U-shaped antitheft device, the support members 11
are connected to the bar member 2 (the body 6) by tapered pins
(pin members) 12 provided in boundary portions between the
support members 11 and the bar member 2 (the body 6) in the plane
where the respective axes of the insertion holes 8, the rod hole
9 and the lock hole 10 formed in the bar member 2 exist, the
tapered pins 12 being knocked into the boundary portions
perpendicularly to the plane.
Patent EP-1059579-A2 (EP)
Inventor: SUGIMOTO HIDEKI
IPC: G06F9/30
Filed: 2000-06-05
Abstract: An information processor has a first register file
(12) used when a first instruction is executed and a second
register file (13) used when a second instruction is used.
When the second instruction is called from the first
instruction, the second register file (13) is activated and
the first register file (12) is deactivated, when the
second instruction is called from said first instruction.
So, when the second instruction is executed, if a data used
in the second instruction is not written into the second
register file (13), the data is obtained from the first
register file (12), and if it is written, the data is
obtained from the second register file (13). Then, the
execution result of the second instruction based on the
obtained data is written into the second register file (13).
Accordingly, it is possible to provide an information
processor that can quickly switch the register files
without the influence of the number of parameters to be
transferred, and a method for switching the register files.
Patent EP-1071033-A2 (EP)
Inventor: ACOSTA JORGE L
IPC: G06K7/10
Filed: 2000-07-18
Abstract: A method of and a system for generating a dense pattern of scan lines. In a
preferred configuration, multiple laser beams are formed and directed along offset
outgoing paths onto a scanning mechanism such as a polygon mirror which scans the
beams across pattern mirrors to generate simultaneous scan patterns out into the scan
volume. Return light from both scan patterns are retrodirectively collected and redirected
by a common collection element such as a collection lens. The collection lens focuses
return light from the first beam onto a first detector and light from the second beam onto a
second detector, the first and second detectors being offset in corresponding fashion to the
offset of the outgoing beams.
Patent EP-1054178-A2 (EP)
Inventor: SATO EICHI
IPC: F16D41/07
Filed: 1995-10-06
Abstract: The invention relates to an end bearing for a one-way
clutch which is preferred for use in an automatic transmission.
The end bearing of the invention comprises a body formed of a
steel sheet, a hard coating applied to the surface of the body,
and a soft coating formed on the surface of the hard coating. In
the end bearing of the invention, a sufficient rigidity can be
secured as a result of forming the body from a steel sheet. A
region which provides a sliding surface is coated by a soft
coating and a hard coating. Accordingly, there is provided an
end bearing which exhibits an excellent anti-seizure resistance
and durability.
Patent EP-1100005-A2 (EP)
Inventor: HEISTERMANN HORST
IPC: G06F9/44
Filed: 2000-08-03
Abstract: Known techniques for generating serial information to represent program objects
(serialization) and to recreate program objects from the serial information
(deserialization) often impose limitations on the changes that may be made to the class
structure or definition of the program object. Many changes to the class structure
introduce incompatibilities that prevent a one version of a program object from being
recovered from serial information that represent a different version of the program object.
Techniques are disclosed that overcome this difficulty by allowing the serialization and
deserialization processes to be adaptive according to the version of the program object.
Patent EP-1079109-A2 (EP)
Inventor: FUKUSHIMA SHIGEO
IPC: F04B39/00
Filed: 2000-08-24
Abstract: A die-cast piston (14) for a swash plate type compressor including
a cylinder block (10) having a cylinder bore (12), including a
generally cylindrical head portion (82) slidably movably received
in a cylinder bore (12) formed in a cylinder block (10) of the
compressor, and a generally U-shaped neck portion (80) having a
base section (140) and a pair of substantially parallel arm
sections (144, 146) which extend from the base section, wherein
the base section (140) has an inner surface (142) including at least
one as-cast surface area (156) formed in a die-casting process.
Patent EP-1058489-A2 (EP)
Inventor: RAAIJMAKERS IVO
IPC: H05H1/46
Filed: 1996-11-14
Abstract: A method and apparatus for generating a plasma by
inductively coupling electromagnetic energy into the
plasma in a vacuum chamber (100). In one embodiment,
first and second antenna coils (104, 106) are disposed
about the circumference of the plasma containment
area. The first and second antenna coils are
relatively spaced along the longitudinal axis of the
plasma containment area by a distance (2). A current
is generated in the first and second antenna coils
through amplifiers and matching networks (102, 108;
106, 112) and a single RF generator (114). A phase
shift regulating network (116) establishes a
difference between the phase of the current in the
first antenna and the phase of the current in the
second antenna. The phase difference corresponds to
the phase difference required to launch a helicon wave
in the plasma. In a second embodiment, a chamber
shield (118) is made of a conductive material and is
coupled to the RF source such that the shield
functions as an RF antenna. The shield may be coupled
in series to a coil surrounding the shield to increase
the resultant flux density.
Patent EP-1099587-A2 (EP)
Inventor: HAMBUSCH THORSTEN
IPC: B60J7/20
Filed: 2000-10-28
Abstract: The handle is mounted on an adjustment device to pivot between a non-operating position and an operating position in which a force or torque can be applied to the adjustment part. The handle is biased towards the non-operating position by a spring. A damper damps handle motion into the non-operating position caused by the spring. The handle can be pivotably mounted on a bracket fixed to the adjustment part either permanently or removably. The handle (1) is pivotably mounted on an adjustment device to pivot between a non-operating position and an operating position in which a force or torque can be applied to the adjustment part via the handle. The handle is biased towards the non-operating position by a spring (4) and a damper (5) damps the movement of the handle into the non-operating position caused by the spring. The handle can be pivotably mounted on a bracket (8) that is fixed to the adjustment part either permanently or removably.
Patent EP-1106456-A2 (EP)
Inventor: VOGT GERHARD
IPC: B60S1/52
Filed: 2000-11-27
Abstract: The windscreen cleaning device has a cap(3) enclosing the nozzle unit(2) and inside of which the nozzle unit is adjustable. On at least one side the cap has at least one through-opening(13) for the cleaning fluid sprayed from the nozzle unit. The cap has a cover section(11) which is surface treated, coated or lacquered. The nozzle cap has a retaining section(12) which fits in a cut-out in a body part of the vehicle and which has bearing elements(20) for movable mounting of the nozzle unit.
Patent EP-1118415-A2 (EP)
Inventor: HSU CHRISTOPHER
IPC: B23K9/10
Filed: 2000-12-21
Abstract: In an electric arc welder for creating an arc welding process between a consumable electrode
advancing through a contact tip and a workpiece, the welder including a power supply to create an
arc current and arc voltage and having a first lead connected to the contact tip and a second lead
connected to the workpiece, the improvement comprising dividing the contact tip into an upper tip
section and a lower tip section with an insulator electrically isolating the sections, a first switch
selectively shiftable to a conductive state connecting one of the power supply leads to said upper tip
section, a second switch selectively shiftable to a conductive state connecting the one lead to the
lower tip section and a switch operating network creating a first switch signal to shift the first switch
to its conductive state and/or a second switch signal to shift the second switch to its conductive state
to control the effective CTWD of the arc welding process.
Patent EP-1004742-A2 (EP)
Inventor: VAN DER WIELEN FRANSISCUS JOHA
IPC: E06B9/382
Filed: 1997-06-11
Abstract: The invention relates to a venetian blind, comprising: a plurality of parallel and
horizontally extending slats which are mutually connected by means of suspension
means, and gathering means for gathering the slats together into a package, wherein the
gathering means are adapted to form the package on the upper part of the venetian
blind, wherein a cleaning device is arranged for cleaning the slats, wherein the cleaning
device is arranged on the upper part of the venetian blind below the position where the
package of slats is formed.
Patent EP-1038642-A2 (EP)
Inventor: LYNCH RICHARD J
IPC: B26D7/18
Filed: 2000-02-28
Abstract: A chaff collection apparatus (60) includes a chaff tray (62)
coupled to the internal drum (20) below the side punches (50). The
chaff tray (62) includes a cover (64) comprising a plurality of
evenly spaced frangible fingers (66). A specific set of the
fingers (66) is removed from the cover (64) according to the
locations of the side punches (50) on the internal drum (20). In
this manner, only the portions of the cover (64) below the side
punches (50) are open to the interior of the chaff tray (62). The
chaff produced by each punch (50) passes into the chaff tray (62)
through a respective opening (68) in the cover (64), and is captured
within the chaff tray (62). The areas of the cover (64) of the chaff
tray (62) that are not located below the side punches (50) remain
covered by the remaining frangible fingers (66), thereby preventing
chaff from escaping the chaff tray (62).
Patent EP-1095751-A2 (EP)
Inventor: XIA ZHOUXUAN
IPC: B29C43/02
Filed: 2000-11-01
Abstract: A forming assembly includes an articulatable support insertable into a
curved bore of an air flow assembly such as a throttle body system (10) having a
valve disc (16) within a curved bore. The articualtable support is inserted into the
bore from one side of the valve disc (16), and another support is inserted into the
bore on the other side of the disc. The articulatable support (26) includes a first
portion (32) movable relative to a second portion (34) such that the support fits through
a bore portion that is relatively more narrow than an outer periphery of the
valve disc (16). The articulatable support (26) is then expanded to be correctly position
to engage the disc adjacent the disc outer periphery.
Patent EP-1047280-A2 (EP)
Inventor: PROCTOR RICHARD JOHN
IPC: H04Q11/04
Filed: 2000-03-27
Abstract: A communications system comprising a common device (e.g. an ATM physical layer (PHY)) and higher layer devices (e.g. an ATM layer and an AAL2 layer) are connected via a bus for communication of traffic therebetween, the bus comprising lines for carrying data and control signals. The bus supports data in ATM form and AAL2 form and the devices comprise discrimination means for discriminating between the two forms of data traffic. The data in AAL2 form typically comprises AAL2 mini-cells associated with a means of identification of the source or destination of the mini-cells. <IMAGE>
Patent EP-1049073-A2 (EP)
Inventor: ERZIN ENGIN
IPC: G10L19/107
Filed: 2000-04-20
Abstract: A fixed codebook response is able to better characterize an input signal of a
vocoder because the entries of the fixed codebook are tailored to the input signal
being processed. A uniformly distributed random noise signal is stored in a
transmitting vocoder. During encoding by the transmitting vocoder, the noise signal
is shaped by a weighing filter and a pitch sharpening filter, which are condition
controlled by the linear predictive coding, pitch and pitch gain characteristics of the
input signal being encoded. The shaped noise signal is passed though a thresholding
filter to arrive at a pulse sequence having a given sparcity. The fixed codebook
response is chosen as that portion of the pulse sequence which best matches a
residual signal of the input signal. The indexed location of that portion along the
pulse sequence is designated as the fixed codebook bits which are included within the
bit frame. The identical random noise signal is stored in a receiving vocoder. The
linear predictive coding, pitch, and pitch gain characteristics are part of the bit frame,
and are again used to produce an identical pulse sequence. The fixed codebook bits
of the bit frame are used to index the pulse sequence to the best matching portion,
and hence the fixed codebook response for the bit frame.
Patent EP-1081144-A2 (EP)
Inventor: NORRIS TIMOTHY
IPC: C07D/
Filed: 2000-08-17
Abstract: A process is described for preparing a compound of Formula (1.3.0):
 
comprising: establishing a reaction mixture consisting of
 
in an aprotic solvent; in the presence of NaOH or KOH; optionally in the presence of a phase
transfer catalyst, especially a quaternary ammonium salt or a phosphonium salt; followed by
heating said reaction mixture under a nitrogen atmosphere;
   in a preferred embodiment the aprotic solvent is DMSO, the strong base in solid form
is NaOH in powder or pellet form, and the phase transfer catalyst is tetra- n -butylammonium
chloride (TBAC); 
wherein the starting material of Formula (2.0.0) is prepared as follows:
 
are reacted together in a solvent consisting of a straight or   branched chain aliphatic alcohol; in the presence of a strong
base consisting of NaOH or KOH; further in the presence of
a transition metal catalyst comprising a palladium metal
complex; and still further in the presence of an auxiliary
ligand comprising a bidentate, chiral, axially dissymmetric
aromatic compound of Formula (5.5.0) or (5.5.1):
Patent EP-1111376-A2 (EP)
Inventor: SONE YUUYA
IPC: H04W84/02
Filed: 2000-12-13
Abstract: The problem the present invention sets out to resolve is to detect events regardless of the
condition of the system operation, and notify one or a plurality of users at remote locations
of the detected events using a message. To solve the above problem, apparatus relating to
the present invention comprise a measurement module with a heating furnace installed, a
measurement station with a measurement user interface for controlling the measurement
module, a personal computer or a workstation connected to the measurement station via
communication media, a pager connected to the measurement station via a public
telephone line, and a software operating on a central processing units installed in the
measurement module, the measurement station, and the personal computer or the
workstation.
Patent EP-1077175-A2 (EP)
Inventor: LARSSON MATS
IPC: F16F9/16
Filed: 2000-07-06
Abstract: A telescopic fork arrangement comprises at
least two telescopic legs, each having telescopically
arranged tubes (7, 8, 13) and, arranged in these,
piston and piston-rod arrangements (10, 12) operating
in a working medium. The first telescopic leg (e.g. 5)
performs a damping function essentially only during its
compression movement, and a second telescopic leg (6)
performs a damping function essentially only during its
return movement. The telescopic legs are connected to a
respective pressure chamber unit (25) which, in a
closed system for the working medium, formed with the
respective leg in question, keeps this working medium
pressurized. A piston (12) in the piston/piston-rod
arrangement is provided with or cooperates with one or
more members (29, 30, 36, 37) which perform or
determine respective damping functions, and of which
one or more are adjustable from the outside.