baber/WOPTO huggingface dataset:
Patent CA-2409219-A1 (CA)
Title: Regulateurs cellulaires d'agents infectieux et methodes d'utilisations
Inventor: BARBER JACK R
IPC: A61K38/00
Filed: 2001-05-02
Abstract: L'invention concerne des ribozymes contenant des séquences de reconnaissance de cible permettant au ribozyme de cibler puis de couper des régulateurs cellulaires impliqués dans une réplication du virus de l'hépatite C (HCV) ou d'autre virus. Elle concerne aussi des acides nucléiques codant pour différents régulateurs cellulaires, des séquences dans de tels acides nucléiques pour lesquelles des ribozymes peuvent être dirigés, ainsi que des fragments des ces séquences d'acides nucléiques et de protéine. Elle concerne aussi une méthode d'identification d'un ribozyme réactif avec un régulateur d'expression ou de réplication virale, une méthode d'identification du régulateur cellulaire ciblé par de tels ribozymes, ainsi qu'une méthode d'identification d'un composé qui module l'activité d'un régulateur cellulaire. Elle concerne enfin une méthode de traitement d'une infection par HCV.
Patent CA-2409713-A1 (CA)
Inventor: SNYDER EVAN Y
IPC: C12N5/08
Filed: 2001-04-25
Abstract: The present invention provides human neural crest stem cells which are pluripotent, self-renewing, and can be maintained as a stable cell line via retrovirus-mediated vmyc gene transfer. These human neural crest stem cells and their daughter progeny cells are uncommitted and undifferentiated cells which can subsequently be induced to a range of alternative recognized types of differentiated and functional cells including neurons, Schwann cells, adrenal chromaffin cells, and skeletal muscle cells.   These human neural crest stem cells and their progeny cells are suitable for implantation in-vivo for cell therapy treatment of human neurological disorders and diseases.
Patent CA-2409806-A1 (CA)
Title: Modified asphalt cement and process for preparing same
Inventor: HAGENS GRAHAM
IPC: C10C3/02
Filed: 2002-10-25
Abstract: A method is described for the preparation of improved "multigrade" asphalt cement by a combination of gelled and polymer modified asphalt technologies. An optimum mixture of fatty acids, elastomeric polymers and neutralization aids described provide superior performance at greatly reduced cost. This is accomplished by saponifying a dispersion of at least one fatty acid with excess alkali metal base such that the total quantity of alkali does not exceed three times the stoichiometric quantity required for neutralization, and such that the excess alkali is composed of an alkali silicate. Further improvement in properties may also be obtained if one or more synthetic elastomeric polymers are included in the composition. The resulting chemically modified asphalt may be utilized in conventional processes in road, roofing and specialty applications.      The asphalt cement may be prepared and applied using conventional hot-mix asphalt processes and manufacturing equipment.
Patent CA-2409883-A1 (CA)
Inventor: LEWIS GARY
IPC: C05G5/23
Filed: 2002-10-29
Abstract: A system is provided for extracting nitrogen compounds from combustion exhaust gases, which is particularly suited for use with an agricultural irrigation system. The system includes an exhaust chamber in communication with the motor driving the irrigation pump of the irrigation system for receiving the exhaust gases therethrough. Water is injected into the exhaust chamber for mixing with the exhaust so that the steam being formed absorbs various nitrogen compounds from the surrounding hot exhaust gases. The steam is subsequently condensed in a condensing chamber from which condensate is collected and dispensed into the inlet of the irrigation pump with the irrigation water. The irrigation water is thus enriched with various nitrogen compounds absorbed from the exhaust gases. A catalytic converter may be coupled in series with the exhaust chamber for extracting certain desirable nitrogen compounds in the condensate.
Patent CA-2410259-A1 (CA)
Title: Hydrophilic coating including dlc on substrate
Inventor: VEERASAMY VIJAYEN S
IPC: B32B17/10
Filed: 2001-05-22
Abstract: A substrate is coated with a hydrophilic layer(s) or coatings(s) that includes, for example, amorphous carbon in a form of diamond-like carbon (DLC). In certain embodiments, the DLC inclusive layer may be doped with at least one polar inducing dopant (e.g., Boron, Nitrogen, and/or any other suitable polar inducing dopant) in order to make the layer more polar and thus more hydrophilic so as to have a lower contact angle .theta. (e.g., no greater than about 10 degrees in certain embodiments, and more preferably no greater than about 8 degrees).
Patent CA-2410485-A1 (CA)
Title: Thrombospondin-1 type 1 repeat polypeptides
Inventor: LAWLER JOHN W
IPC: A61P35/00
Filed: 2001-05-25
Abstract: Thrombospondin-1 (TSP-1) is a potent inhibitor of tumor growth and angiogenesis. To elucidate the molecular mechanisms that are involved in the inhibition of tumor growth by the type 1 repeats (TSRs), recombinant versions of these motifs have been produced and have been assayed for their ability to inhibit the growth of experimental B16F10 and Lewis lung carcinomas.  Recombinant proteins that contain all three TSRs (3TSR) or the second TSR with (TSR2+RFK) or without (TSR2) the transforming growth factor beta (TGF.beta.) activating sequence (RFK) have been expressed in <i>Drosophila</i> S2 cells. A  recombinant protein containing all three type 1 repeats of TSP-2 and a recombinant protein containing the second TSR with the RFK sequence altered to QFK have also been produced. The data indicate that the TSRs inhibit tumor growth by inhibition of angiogenesis and regulation of tumor cell growth and apoptosis. The regulation of tumor cell growth and apoptosis is RFK-dependent while the inhibition of angiogenesis is not. The invention relates to polypeptides based on the amino acid sequence of human TSP-1 type 1 repeats.  The polypeptides, variants, fragments and mutants thereof can be made by recombinant methods or can be made by chemical synthesis. The polypeptides can be formulated into pharmaceutical compositions and used in methods of therapy to reduce tumor growth.
Patent CA-2410795-A1 (CA)
Title: A method for the amplification of multiple genetic targets
Inventor: LEM PAUL
IPC: C12Q1/68
Filed: 2002-12-10
Abstract: A method for simultaneous amplification and detection of multiple genetic targets is provided.      Furthermore, a primer design protocol specific to the PCR reaction conditions of the present invention is also provided. The method of the present invention includes a PCR reaction mixture and primers specifically selected according to the reactions conditions provided. Multiple genetic targets are amplified simultaneously by this method, without requiring optimization of the reaction conditions.
Patent CA-2411989-A1 (CA)
Title: Optimized fiber reinforced liner material for positive displacement drilling motors
Inventor: HACHE JEAN-MICHEL
IPC: B29C70/34
Filed: 2002-11-18
Abstract: A method of forming a stator for a positive displacement motor. The method includes forming a liner that includes at least two resilient layers and at least one fiber layer, and the at least two resilient layers are positioned so as to enclose the at least one fiber layer. The liner is positioned in a stator tube, and the stator tube includes a shaped inner surface including at least two radially inwardly projecting lobes extending helically along a selected length of the stator tube. The liner is cured in the stator tube so that the liner conforms to the radially inwardly projecting lobes formed on the inner surface and to the helical shape of the inner surface. The curing forms a bond between the liner and the inner surface and between the at least two resilient layers and the at least one fiber layer.
Patent CA-2413249-A1 (CA)
Inventor: KESAVAN SUNIL KUMAR
IPC: C09K3/14
Filed: 2001-06-18
Abstract: Friction materials which contain at least one fluoropolymer material for use in friction linings for applications such as, but not limited to brake disk pads, are described. The fluoropolymer material, such as, but not limited to PTFE, FEP, and PVDF, is preferably present in an amount of from about 0.1 to about 5 weight percent, based on the total weight of the friction material matrix.
Patent CA-2415430-A1 (CA)
Inventor: NGUYEN NGHI VAN
IPC: H04W4/24
Filed: 2001-07-10
Abstract: L'invention concerne des procédés de protection de fibres kératiniques d'un dommage extrinsèque et/ou de réparation de ces fibres kératiniques endommagées par des conditions extrinsèques en appliquant sur ces fibres kératiniques une composition composée d'au moins un sucre sélectionné parmi des monosaccharides C3 à C5 et des dérivés de ces monosaccharides. Un dommage extrinsèque est un dommage provoqué par des conditions comme le soleil, les dommages chimiques, par exemple, dus à des détergents, des décolorations, des défrisages, des teintures et des permanentes et la chaleur par exemple, celle provenant de séche-cheveux ou de fers à friser. Les exemples de fibre kératinique incluent les cheveux, les cils et les sourcils.
Patent CA-2415729-A1 (CA)
Title: High temperature resistant magnesium alloys
Inventor: BRONFIN BORIS
IPC: C22C23/06
Filed: 2002-12-31
Abstract: A magnesium-based alloy containing at least 92 wt% magnesium, 2.7 to 3.3 wt% neodymium, 0.0 to 2.6 wt% yttrium 0.2 to 0.3 wt% zirconium, 0.2 to 0.8 wt% zinc, 0.03 to 0.25 wt% calcium, and 0.00 to 0.001 wt% beryllium. The alloy may additionally contain up to 0.007 wt% iron, up to 0.002 wt% nickel, up to 0.003 wt% copper, and up to 0.01 wt% silicon, and incidental impurities. The alloy may contain from 0.2 to 0.5 wt% Zn, and from 0.0:3 to 0.15 wt% Ca. and 2.9-3.2 wt% Nd, 1.9-2.1 wt% Y, 0.3-0.5 wt% Zr, 0.2-0.4 wt% Zn, and 0.03-0.12 wt% Ca.
Patent CA-2416873-A1 (CA)
Inventor: RENAUD MICHEL
IPC: C12Q1/68
Filed: 2001-07-20
Abstract: The invention concerns a method for detecting micro-organisms constituting a flora of micro-organisms, whereof at least part of the elements has a common operon. The invention is characterised in that it consists in identifying the elements of said flora by studying the intergenetic sequence of said operon, and the support exhibiting nucleic acids capable of hybridizing said intergenetic sequence.
Patent CA-2419131-A1 (CA)
Inventor: SHEEHAN PATRICK K
IPC: G06F3/12
Filed: 2003-02-18
Abstract: A system for installing a printer driver for a printer connected on a network, includes a link for accessing an installer, wherein the link is displayed in a host device connected on the network in a web page generated by a web server resident on the printer; a printer driver for the printer; an identifier for uniquely identifying the printer on the network, wherein, responsive to activating the link, the identifier stores the printer's unique identification on the host device; and an installer, responsive to activating the link and to receipt of the printer's unique identification, for installing the printer driver on the host device.
Patent CA-2421280-A1 (CA)
Title: Biodegradable molded article, manufacturing method thereof, and composition for expansion molding
Inventor: SHINOHARA RUMI
IPC: B65D65/46
Filed: 2001-09-12
Abstract: Biodegradable molded articles; a process for producing the same: and compositions for foam molding packed in a packaging film bag to be used in the production. A bowl-type container (10a), which is one of the biodegradable molded articles as described above, consists of a bowl body (11a) comprising starch as the main component and a coating film (12) having at least hydrophobic properties and comprising a biodegradable plastic as the main component which is bonded to the surface of the bowl body (11a). This bowl body (11a) is formed by steam-foaming molding a material to be molded which is in the form of a slurry or a dough containing starch and water. The coating film (12) is closely bonded to the surface of the bowl body (11a) either directly or via an adhesive layer. Compositions for foam molding packed in such packaging film bags can be easily stored and molded.
Patent CA-2421914-A1 (CA)
Title: Separable laminated container and associated technology
Inventor: NOMOTO TSUGIO
IPC: B65D77/06
Filed: 1996-03-06
Abstract: A separable laminated container (A) of the present invention comprises an outer layer (1) made of synthetic resin and having an air suction hole (10) and an inner layer (2) made of synthetic resin and separably laminated on the inside of the outer layer, the inner layer having a portion previously separated from the outer layer just around the air suction hole. The air suction hole can be formed by driving a punch into the outer layer at a neck (4) of the separable laminated container from the outside, and punching just the outer layer leaving the inner layer behind. The portion of the inner layer previously separated from the outer layer may be left in the inwardly extended state. The inner layer is preferably made of synthetic resin having flexural modules of less than 10,000 kg/cm2.
Patent CA-2422274-A1 (CA)
Title: Butt splicing tapes and butt splicing methods
Inventor: SHAW ROBERT G
IPC: B65H19/18
Filed: 2001-08-29
Abstract: Butt splicing tape comprising:a splicing portion, an attachment portion and a gripping portion, wherein said splicing portion comprises an elongated first backing member (10) having two faces and two longitudinal edges, a first adhesive layer (11') on the first face of said first backing member (10), said first adhesive layer (11') extending substantially along the first longitudinal edge of said first backing member (10) and optionally being covered by a first release liner (12), and a second adhesive layer (11") on the first face of said first backing member (10), said second adhesive layer (11") extending substantially along the second longitudinal edge of said first backing member (10) and being covered by a second release liner (13) having two faces and two longitudinal edges, the first face of said second releaser liner (13) being adjacent to second adhesive layer (11"); wherein said attachment portion (20, 21) is connected to said splicing portion, and includes a third adhesive layer (31) and is connected to said second release liner (13) of splicing portion.
Patent CA-2424776-A1 (CA)
Title: Washing and dewatering of suspensions
Inventor: VAN DER WEERD HENDRIK
IPC: C08B31/18
Filed: 2001-10-08
Abstract: The invention relates to a process for washing and dewatering starch suspensions in a single step using a vacuum filter. It also relates to a rotary vacuum drum filter having means for feeding a suspension, sprayers fo r applying washing liquids and a scraper.
Patent CA-2425646-A1 (CA)
Inventor: SUNKARA HARI BABU
IPC: D03D15/56
Filed: 2002-10-24
Abstract: A polyether ester elastomer comprising about 90 - about 60 weight %  polytrimethylene ether ester soft segment and about 10 - about 40 weight %  tetramethylene ester hard segment, and use thereof in fibers and other shaped articles. The fibers have excellent physical properties, including superior strength and stretch recovery.
Patent CA-2426742-A1 (CA)
Inventor: THONNARD JOELLE
IPC: C12N15/31
Filed: 2001-10-24
Abstract: The invention provides BASB210 polypeptides and polynucleotides encoding BASB210 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
Patent CA-2427770-A1 (CA)
Title: Apparatus for testing jack legs and air drills
Inventor: BOTNAN TED R
IPC: G01M99/00
Filed: 2003-05-02
Abstract: An apparatus for testing for air and water leakage in jack legs and air drills used to bore holes in rock and ore has an upright beam supporting a weight vertically movable with expansion of the jack leg. A test stand has a plurality of valves operable to divert air to the jack leg and air drill. Gauges on the test stand monitor the air pressure in the jack leg and air and water pressures in the air drill to provide information as to air and water leakage and defective parts in the jack leg and air drill.
Patent CA-2429059-A1 (CA)
Inventor: FALOTICO ROBERT
IPC: A61L31/08
Filed: 2003-05-20
Abstract: A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia following percutaneous transluminal coronary angiography. The local delivery of the drugs or agents provides for increased effectiveness and lower systemic toxicity.
Patent CA-2430739-A1 (CA)
Inventor: CASONI ANDREA
IPC: F02C7/18
Filed: 2001-12-05
Abstract: A system to feed cooling air to a gas turbine, wherein the cooling air is taken from a high-pressure source, inside the gas turbine, and is conveyed to radial accelerators (12), which give rise to the tangential acceleration of the air in the direction of the peripheral motion of the rotor surface. After it has been accelerated to the peripheral sepped of the rotor, the cooling air enters radial holes (13), and, whilst passing radially through the radial holes (13), undergoes a reduction in the quantity of tangential motion, Subsequently, the cooling air is released into the hollow rotor, with a correspondingly reduced outlet radius (14). A series of labyrinth seals combined with brush seals separate the chamber for combined with brush seals separate the chamber for feeding of air to the radial holes (13), from the low-pressure environment around the pad #2 (15) of the said gas turbine.
Patent CA-2432302-A1 (CA)
Title: Element servant a assembler des modules avec ancrage magnetique pour la construction de structures de grille stables
Inventor: VICENTELLI CLAUDIO
IPC: F16B1/00
Filed: 2002-03-18
Abstract: Dans un assemblage de modules avec ancrage magnétique pour la construction d'une structure de grille, un élément d'assemblage (11, 11''', 11'''') servant à relier de manière rigide au moins un premier et un second module allongé (3, 3''', 3'''') de la structure de grille se caractérise en ce qu'il comprend: un corps de l'élément d'assemblage (11, 11''', 11''''); au moins une première et une seconde partie en saillie tubulaire (15, 15''', 15'''') dudit corps permettant la fixation axiale respectivement du premier et du second module allongé (3, 3''', 3''''); et un boîtier (14, 33, 36) dudit corps servant à maintenir ledit corps sur une autre module (1, 1', 39) de ladite structure de grille. Selon l'invention, lesdites première et seconde parties en saillie tubulaires (15, 15''', 15'''') se trouvent en communication directe avec ledit boîtier (14, 33, 36) afin de permettre le contact entre ledit autre module (1, 1', 39) et lesdits premier et second modules allongés (3, 3''', 3'''').
Patent CA-2432454-A1 (CA)
Inventor: MAGGI LUIGI MAX
IPC: F16F7/10
Filed: 2003-06-16
Abstract: The invention proposes to address the vibration transfer function transmitted by a turbo-fan engine or equivalent to the aircraft structure, with two types of isolators mounted on a unique assembly but with a different physical response to the transfer function, an absorbing one and a resonating one. The difference in nature of such responses induces a non- interaction effect between the two isolators. The invention concerns more specifically a two-tone isolator assembly adapted to be mounted on an aircraft or equivalent comprising in particular a head, a cabin yoke and a power engine structure having a longitudinal axis crossed by a radial plan. The two-tone isolator assembly comprises, located at the head side of the aircraft, at least one support for at means to couple said support to the power engine structure and to the cabin yoke. Said assembly is designed to link the fluid mount isolator at once to the power engine structure and to the cabin yoke, whereas the dynamic absorber is only linked to the cabin structure. Furthermore, the dynamic absorbers are supported to move in the radial plan of the power engine structure.
Patent CA-2432492-A1 (CA)
Title: Linked manufacturable, non-plugging microcircuits
Inventor: DRAPER SAMUEL DAVID
IPC: F01D9/02
Filed: 2003-06-16
Abstract: A linked microcircuit for providing coolant gas flow through an aircraft part, comprising at least one inlet through which a coolant gas may enter, a circuit channel extending from the at least one inlet through which the coolant gas may flow wherein the circuit channel is formed from the superimposition of a plurality of alternating serpentine circuits, and at least one outlet appended to the circuit channel through which the coolant gas may exit the circuit channel.
Patent CA-2434968-A1 (CA)
Inventor: PALSSON BERNHARD O
IPC: G16B5/00
Filed: 2002-01-31
Abstract: The present invention relates to methods for achieving an optimal function of a biochemical reaction network. The methods can be performed in silico using a reconstruction of a biochemical reaction network of a cell an iterative optimization procedures. The methods can further include laboratory culturing steps to confirm and possibly expand the determinations made using the in silico methods, and to produce a cultured cell, or population of cells, with optimal functions. The current invention includes computer systems and computer products including computer-readable program code for performing the in silico steps of the invention.
Patent CA-2437558-A1 (CA)
Title: Method and apparatus for the confinement of materials in a micromachined chemical sensor array
Inventor: SHEAR JASON B
IPC: G01N33/53
Filed: 2002-01-31
Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle. Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
Patent CA-2438057-A1 (CA)
Inventor: PSAROS GEORGIOS
IPC: A01K89/016
Filed: 2002-01-24
Abstract: A fishing reel (104) and spool (106) can be made as a more versatile kit (102) in that the fishing reel (104) includes a locking system adapted to interact with a circumferential area of the spool (106). changing spool (106) becomes easier with no loose parts and alternating between left and right hand becomes possible.
Patent CA-2438118-A1 (CA)
Inventor: YASHIRO KOJI
IPC: C12P21/02
Filed: 2002-02-07
Abstract: Vecteur plasmide navette caractérisé en ce qu'il possède un ADN codant une séquence qui est réplicable dans une bactérie qui appartient au genre Brevibacillus et Escherichia coli et qui est capable de servir de promoteur dans Brevibacillus ainsi que de marqueur de sélection pour E. coli et Brevibacillus ; et procédé pour transformer Brevibacillus en utilisant le vecteur plasmide navette. Ce vecteur plasmide navette permet la transformation efficace de Brevibacillus. Le vecteur plasmide navette, pNCMO2, comprend un domaine régulateur d'expression génique sécrété et exprimé dans Brevibacillus ; son expression est cependant remarquablement inhibée dans E. coli. De cette manière, le vecteur plasmide navette permet de construire efficacement un plasmide d'expression génique recombinant en utilisant E. coli et s'avère efficace pour la production d'une protéine dans Brevibacillus.
Patent CA-2438423-A1 (CA)
Inventor: SAGER RONALD E
IPC: G01N33/487
Filed: 2002-02-12
Abstract: Apparatus for detection and measurement of agglutinations of magnetic particles employing Hall sensors (15, 16). A low frequency AC signal (24) is employed to excite or bias the Hall sensors which reside in a DC magnetic field (23). The particles are moved into operative relationship with the Hall sensors in order to generate a signal representing the number of particles on the substrate (22). The method for such detection and measurement is also part of the invention.