baber/WOPTO huggingface dataset:
Patent WO-2020077136-A1 (WO)
Inventor: TSAO CAROLINE
IPC: C07K2/00
Filed: 2019-10-10
Abstract: Charged polypeptides, their conjugates, and fusion proteins comprising such polypeptides are disclosed. Inclusion of such a polypeptide in a fusion protein increases the protein's properties such as stability and circulation half-life, which results in a better therapeutic efficacy compared to an active protein alone. Thus, a fusion protein or a conjugate of the disclosure can be useful in developing a protein or peptide drug, treating or preventing diseases, disorders, or conditions, or improving a subject's health or wellbeing.
Patent WO-2021080587-A1 (WO)
Title: Additive manufacturing machines comprising focused and unfocused energy sources
Inventor: BARNES ARTHUR H
IPC: B33Y30/00
Filed: 2019-10-24
Abstract: In some examples, an additive manufacturing machine includes an unfocused energy source to heat portions of a layer of build material as the unfocused energy source moves across the layer of build material during a build operation of a three-dimensional (3D) object. A focused energy source is controllable to selectively direct focused energy on the layer of build material during the build operation.
Patent WO-2020097396-A1 (WO)
Inventor: GRAY NATHANAEL
IPC: C07D213/06
Filed: 2019-11-07
Abstract: The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase  (e.g. , Janus kinase (JAK),  e.g ., Janus kinase 2 (JAK2)) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits ( e.g. , for treating a disease ( e.g. , proliferative disease) in a subject in need thereof).
Patent WO-2020102085-A1 (WO)
Inventor: WEIDMAN TIMOTHY WILLIAM
IPC: G03F7/11
Filed: 2019-11-11
Abstract: Imaging layers on the surface of a substrate may be patterned using next generation lithographic techniques, and the resulting patterned film may be used as a lithographic mask, for example, for production of a semiconductor device.
Patent WO-2020112706-A1 (WO)
Title: 7-, 8-, and 10-SUBSTITUTED AMINO TRIAZOLO QUINAZOLINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE
Inventor: ZHANG YONGLIAN
IPC: C07D487/18
Filed: 2019-11-26
Abstract: In its many embodiments, the present invention provides certain 7-, 8-, and 10-substituted amino triazolo quinazoline derivatives of Formula (I): or a pharmaceutically acceptable salt thereof, wherein ring A, R1, R2, and R4 are as defined herein, pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other therapeutic agents), and methods for their preparation and use, alone and in combination with other therapeutic agents, as antagonists of A2a and/or A2b receptors, and their use in the treatment of a variety of diseases, conditions, or disorders that are mediated, at least in part, by the adenosine A2a receptor and/or the adenosine A2b receptor.
Patent WO-2020113230-A1 (WO)
Title: Respiratory inhaler cartridge placement training device
Inventor: BAKER JEFF
IPC: G09B9/00
Filed: 2019-12-02
Abstract: In one embodiment, a resettable respiratory inhaler training device is provided herein. The resettable respiratory inhaler training device includes a device housing having an unlocked position and a locked position, the housing comprising a chamber; a cartridge for placement into the chamber, the cartridge comprising a body for insertion into the chamber and a base, said cartridge including a status indicator window to indicate a new or used cartridge, an aperture in the base and a shutter to selectively open or close the aperture; and a reset cap comprising a protrusion for interfacing with the aperture during reset of the device; wherein operation of the device changes the status indicator window from used to new to reset the cartridge for a subsequent use.
Patent WO-2020123477-A1 (WO)
Inventor: MEHTA VIMAL D
IPC: C12Q1/68
Filed: 2019-12-10
Abstract: La présente invention concerne des méthodes de traitement du cancer qui comprennent l'administration, à un patient atteint d'un cancer, d'un inhibiteur sélectif de la dipeptidyle peptidase et d'un agoniste de l'OX40, avec ou sans inhibiteur(s) de point de contrôle immunitaire. La présente invention concerne des compositions pharmaceutiques qui permettent de traiter le cancer et qui comprennent un inhibiteur sélectif de la dipeptidyle peptidase et un agoniste de l'OX40, avec ou sans inhibiteur(s) de point de contrôle immunitaire.
Patent WO-2020146486-A1 (WO)
Title: Predictive maintenance tool based on digital model
Inventor: BONNAIN JEAN-CHRISTOPHE
IPC: G05B23/02
Filed: 2020-01-08
Abstract: An exemplary predictive maintenance method comprises a step of generating a default signature for a machine based on simulations of the machine, a step of comparing the default signature to readings of the machine in operation, a step of determining whether a default will occur to the machine as it continues to operate, and a step of controlling the machine so that it operates in a normal mode or avoids the default.
Patent WO-2020154277-A1 (WO)
Inventor: KIKINIS DAN
IPC: G06Q20/04
Filed: 2020-01-21
Abstract: L'invention concerne un système destiné à mettre en place des systèmes à chaînes de blocs de sécurité dans des situations où au moins une partie des utilisateurs se trouvent sur des réseaux non sécurisés. Le système comprend une passerelle de sécurité qui inspecte des demandes du point de vue de la conformité en utilisant un moteur de règles selon une pluralité de règles et transmet les demandes conformes à leurs destinations prévues respectives. L'inspection de la conformité comprend au moins la vérification de justificatifs d'un émetteur de chaque demande. Une transaction résultant d'une demande est bloquée dans le cas où elle se traduirait par un transfert d'actifs à une adresse n'appartenant pas à une liste blanche sur un réseau non sécurisé.
Patent WO-2021154205-A1 (WO)
Inventor: GUPTA RAMESH
IPC: A61K35/20
Filed: 2020-01-27
Abstract: Le présent développement concerne un réactif de transfection préparé par une interaction ionique d'exosomes dérivés de poudre de colostrum et d'un polycation. La matrice d'exosomes-polycation obtenue, ou EPM, est piégée avec des matériels biologiques, tels qu'un ARNsi, un ARNm, un oligonucléotide antisens ou un ADN plasmidique ou une construction d'expression d'ADN plasmidique.
Patent WO-2021154307-A1 (WO)
Title: Elliptical members
Inventor: MARTIN ROBERT PAUL
IPC: H02J50/00
Filed: 2020-01-31
Abstract: An example charge system may include a human interface device (HID) and a base station. An example HID may include a body member, an elliptical member, a rechargeable power supply, device circuitry, and a charge device embedded within the elliptical member. An example base station may include a housing having a raised, elliptical charge area and a charge device located within the housing at the charge area.
Patent WO-2020167885-A1 (WO)
Inventor: CHANG ERIC HAN KAI
IPC: G06Q20/40
Filed: 2020-02-12
Abstract: La présente invention concerne des systèmes et des procédés permettant de réaliser des paiements à partir d'un véhicule. Selon un mode de réalisation, dans un système de paiement à partir d'un véhicule comprenant une unité d'intégration de paiement qui est connectée à un dispositif électronique mobile, un procédé pour des paiements à partir d'un véhicule peut comprendre : (1) l'unité d'intégration de paiement reçoit une demande de confirmation pour une transaction à partir d'un véhicule en provenance d'une tierce partie ; (2) l'unité d'intégration de paiement reçoit une confirmation de la transaction à partir d'un véhicule en provenance d'un utilisateur de véhicule ; (3) l'unité d'intégration de paiement communique une demande de jeton de paiement d'une dorsale d'institution financière au dispositif électronique mobile, le dispositif électronique mobile communiquant la demande de jeton de paiement à l'institution financière et recevant un jeton de paiement en provenance de l'institution financière ; (3) l'unité d'intégration de paiement reçoit le jeton de paiement en provenance du dispositif électronique mobile; et (4) l'unité d'intégration de paiement communique le jeton de paiement à la tierce partie, la tierce partie effectuant la transaction à l'aide du jeton de paiement.
Patent WO-2020167959-A1 (WO)
Title: Appareils, systèmes et procédés pour supports d'échantillons de microscope
Inventor: GLASER ADAM K
IPC: G02B21/00
Filed: 2020-02-12
Abstract: L'invention concerne des appareils, des systèmes et des procédés pour des supports d'échantillons modulaires. Le microscope peut diriger une lumière d'éclairage le long d'un trajet d'éclairage vers un échantillon et collecter la lumière provenant de l'échantillon le long d'un trajet de collecte. La lumière le long du trajet d'éclairage peut passer à travers un fluide d'immersion et le matériau du support d'échantillon pour atteindre l'échantillon. La lumière le long du trajet de collecte peut passer à travers le matériau du suport d'échantillon et du fluide d'immersion. Le support d'échantillon peut avoir une première surface optique le long du trajet d'éclairage qui est généralement perpendiculaire à un axe optique du trajet d'éclairage. Le support d'échantillon peut avoir une seconde surface optique le long du trajet de collecte qui est généralement perpendiculaire à un axe optique du trajet de collecte. Le support d'échantillon peut être modulaire. Le support d'échantillon peut contenir l'échantillon dans un canal fermé.
Patent WO-2021162709-A1 (WO)
Title: Synchronization priority for sidelink wireless communications
Inventor: LINDHOLM JARI
IPC: H04W56/00
Filed: 2020-02-14
Abstract: According to an example embodiment, a method may include transmitting, by a wireless node in a wireless network, a sidelink synchronization signal (S-SSB) block, including a sidelink primary synchronization signal (S-PSS), a sidelink secondary synchronization signal (S-SSS), a physical sidelink broadcast channel (PSBCH), and a demodulation reference signal (DM-RS), wherein the demodulation reference signal is based on at least a sidelink demodulation reference signal initialization value for the sidelink synchronization signal block to provide sidelink priority-related information for the sidelink synchronization signal block.
Patent WO-2020172337-A1 (WO)
Inventor: MCKIM JAMES
IPC: C12M1/34
Filed: 2020-02-19
Abstract: A method of testing the toxicity of a compound to a specific tissue, the method comprising: growing the tissue three dimensionally in an integrated plate system, contacting the tissue with the compound; and measuring the toxicity of the compound on the tissue.
Patent WO-2020185378-A1 (WO)
Title: Dynamic single channel per carrier with implicit dynamic bandwidth allocation
Inventor: SETHI YOGESH
IPC: H04B7/204
Filed: 2020-02-24
Abstract: A method to provide dedicated bandwidth, the method including: provisioning transmitters to transmit over a satellite link; generating, for each of the transmitters, a respective transmit signal using a common codeblock asynchronous Scrambled Code multiple access (A-SCMA) encoding for a respective information stream; transmitting, via the satellite link, the respective transmit signal from each of the transmitters; and varying a bandwidth rate of each of the respective transmit signals with a grant-free protocol, where the bandwidth rate of the respective transmit signals is less than or equal to a maximum system rate, the transmitting of at least two or more of the transmitters is at least partially concurrent, and each of the respective transmit signals is modulated at a common frequency over a common frequency band with a common polarization. The method reduces latency, jitter, and provides dynamic bandwidth allocation without allocation feedback.
Patent WO-2020231502-A1 (WO)
Inventor: CROWDER WILLIAM
IPC: H04L29/08
Filed: 2020-03-12
Abstract: Examples described herein relate to apparatuses and methods for managing caching for a content delivery system, which may include receiving a content request indicating that the caching agent is requesting content data for a client, filling the content data in a first cache storage of the business logic agent, providing the cached content data to the caching agent, and while a second cache storage of the caching agent is being filled with the content data, maintaining the cached content data in response to receiving additional content requests from the caching agent. The additional content requests may indicate that the caching agent is requesting the same content data for additional clients.
Patent WO-2020190793-A1 (WO)
Title: Compositions and methods for correction of aberrant splicing
Inventor: LUZZIO Michael
IPC: A61K31/53
Filed: 2020-03-13
Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.
Patent WO-2020198426-A1 (WO)
Title: Patterned carrier assemblies having an integrated adhesive film
Inventor: LIE JONATHAN KEVIN
IPC: C09J9/02
Filed: 2020-03-26
Abstract: Introduced here are carrier assemblies that include a rigid tray having a deck area with a patterned surface of cavities for receiving semiconductor components. The cavities can be designed to accommodate semiconductor components of different form factors ( e.g ., having different shapes, sizes, etc.). Moreover, an adhesive film can be affixed to the deck area to ensure that the semiconductor components are securely held against the top surface of the rigid tray. In some instances the adhesive film substantially conforms to the deck area, while in other instances the adhesive film extends across the opening of each cavity located in the deck area. Semiconductor component(s) can be secured to the carrier assembly based on the adhesiveness provided by the adhesive film, mechanical force provided the cavities, electrostatic force provided by the cavities, or any combination thereof.
Patent WO-2020214647-A1 (WO)
Title: Formes solides d'un inhibiteur de protéase du vih
Inventor: SHI BING
IPC: C07D403/14
Filed: 2020-04-15
Abstract: La présente invention concerne des sels pharmaceutiquement acceptables et des formes cristallines de ceux-ci, du composé 1 qui est (S) -2-(4-chloro-3-(l-(difluorométhyl)-lH-l,2,4-triazol-5-yl)phényl)-2- ((R)-4-(4-(2-cyclopropyl-2H-l,2,3-triazol-4-yl)phényl)-2-imino-5- oxo-4-(3, 3, 3-trifluoro-2, 2-diméthyl propyl) imidazolidin-l-yl)éthyl (l-(difluorométhyl)cyclopropyl)carbamate, qui est utile dans le traitement d'une infection Retroviridaeviral notamment une infection provoquée par le virus VIH.
Patent WO-2020236933-A1 (WO)
Title: Multilayer flexible tube and methods for making same
Inventor: LUDLOW JAMES
IPC: F16L11/04
Filed: 2020-05-20
Abstract: A multilayer flexible tube includes an inner layer including a melt processable fluoropolymer, wherein the melt processable fluoropolymer includes a terpolymer including a tetrafluoroethylene, a hexafluoropropylene, and a vinylidene fluoride (THV); a tie layer including a polymeric blend of a terpolymer including a tetrafluoroethylene, a hexafluoropropylene, and a vinylidene fluoride (THV) with a poly vinylidene fluoride (PVDF), a polyamide, a polyetheramide block copolymer, or combination thereof; and an outer layer including a melt processable polymer having a shore hardness less than a shore hardness of the inner layer.
Patent WO-2020243141-A1 (WO)
Inventor: BAR-OR TILLINGER AMIT
IPC: H04W72/12
Filed: 2020-05-27
Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) may receive, within a subframe, a plurality of sidelink control channel signals providing scheduling information for a plurality of sidelink shared channel signals that are also received within the subframe. The UE may determine to use one or more of the plurality of sidelink control channel signals as pilot signals for decoding the plurality of sidelink shared channel signals. The UE may decode the plurality of sidelink shared channel signals based at least in part on the plurality of sidelink control channel signals as pilot signals.
Patent WO-2020247427-A1 (WO)
Inventor: JOHNSON SCOTT EVERT
IPC: E06B3/70
Filed: 2020-06-03
Abstract: A door includes a first skin, a second skin, two stiles, a core, and a gas permeable membrane. The first skin provides a first outer door surface. The second skin provides a second outer door surface. The two stiles are disposed at least partially between the first skin and the second skin. At least one stile defines a vent therein. The core comprises a foam material and is disposed between the first skin and the second skin. The gas permeable membrane, which is permeable to gas but not to the precursors of a foam material, is disposed on the at least one stile covering the vent. The gas permeable membrane contacts the foam material in the core, and separate the foam material in the core from the vent.
Patent WO-2020256989-A1 (WO)
Inventor: JACKSON MARK
IPC: A61B50/39
Filed: 2020-06-08
Abstract: L'invention concerne un revêtement pour un plateau de stockage d'endoscope. Le revêtement a un intérieur comprenant un matériau déformable de manière flexible sensiblement imperméable aux fluides et un matériau absorbant disposé à l'intérieur ou fixé à au moins une partie du matériau déformable de manière flexible. Le revêtement est configuré pour recouvrir temporairement au moins un intérieur du plateau de stockage d'endoscope. L'invention concerne également des systèmes et des procédés.
Patent WO-2020264380-A1 (WO)
Title: Dynamic and automatic agreement generation and modification
Inventor: WICHERN ANDREW A
IPC: G06Q50/18
Filed: 2020-06-26
Abstract: The present disclosure relates generally to systems and methods that can automatically generate agreements and provisions between two or more parties. In one example, the method includes receiving by a processing element a plurality of entity characteristics corresponding to at least one of the two or more parties, analyzing by the processing element two or more of the entity characteristics, utilizing by the processing element the analyzed two or more characteristics to identify a first agreement from two or more agreements, and outputting by the processing element the first agreement to a first user device corresponding to at least one of the two or more parties.
Patent WO-2020264382-A1 (WO)
Title: Tissue ablation using a medical device
Inventor: OSTROOT TIMOTHY A
IPC: A61B18/14
Filed: 2020-06-26
Abstract: An example medical device is disclosed. The medical device includes a catheter shaft including a distal end portion, wherein the distal end portion includes an ablation assembly. The ablation assembly includes an expandable frame including a base, an end region and a plurality of struts extending between the base and the end region, the struts defining a plurality of apertures along the frame. The ablation assembly also includes an electrical circuit coupled to an inner surface of the second end region of the frame, the electrical circuit including a plurality of ablation electrodes coupled thereto. Further, the expandable frame is designed to shift from a delivery configuration in which the ablation electrodes face inward from the inner surface of the expandable frame to an expanded configuration in which the ablation electrodes face away from the base of the expandable frame.
Patent WO-2021011805-A1 (WO)
Inventor: BIRCHFIELD ROBERT CHARLES MASON
IPC: B04B5/10
Filed: 2020-07-16
Abstract: A material separation system is disclosed that may include a vibratory shaker, a centrifuge, a sensor, and/or a processor circuit. The vibratory shaker may be configured to separate a solid-liquid mixture into a first solids-containing component and a shaker effluent. The sensor may be configured to measure a property of one or more of the solid-liquid mixture, the first solids-containing component, the shaker effluent, and the second solids-containing. A well-performance analysis system may be configured to analyze mud reports of drilling rigs within a geographic basin to determine which rigs are performing inefficiently. The system may allow recommendations and send control signals to improve the efficiency of the solid-liquid separation system. The system may allow an operator to view agglomerated well performance data to identify which rigs are performing below a geographic basin baseline and make informed decisions to improve the functioning of a solid-liquid separation system associated with one or more drilling rigs.
Patent WO-2021034850-A1 (WO)
Title: In-situ gel forming ophthalmic formulations containing difluprednate
Inventor: LIANG BO
IPC: A61P27/02
Filed: 2020-08-18
Abstract: The present invention provides aqueous in-situ gel ophthalmic formulations, each including water, difluprednate and a biocompatible polysaccharide, wherein a gel is formed in situ at physiological temperature with instant viscosity increase upon instillation of the formulation into an eye. In the formulations, nanocarriers may be formed by a surfactant or solubilizer contained in the formulation, with or encapsulating difluprednate, and the nanocarriers have an average particle size of 10 to 500 nm or 10 to 150 nm or 10-to 50 nm..
Patent WO-2021035001-A1 (WO)
Title: Particle blast apparatus
Inventor: BROECKER RICHARD
IPC: B05B1/00
Filed: 2020-08-20
Abstract: A particle blast apparatus or system entrains blast media particles from a particle source into a transport fluid which already has blast media particles entrained therein. The system may have, prior thereto, entrained blast media particles into the transport fluid which at that time did not already have blast media particles entrained therein. The particle types may be dissimilar, such as dry ice particles and abrasive media particles.
Patent WO-2022046057-A1 (WO)
Title: Pre-treatment fluid application in printing systems
Inventor: COSTAL FORNELLS PAU
IPC: B41J2/175
Filed: 2020-08-27
Abstract: A printing system may be provided and the printing system may comprise, in an example, a controller, wherein the controller may cause a printing mechanism to selectively apply pre-treatment fluid and marking fluid on a recorded medium. The printing mechanism may comprise a first printhead to dispense pre-treatment fluid and a second printhead to dispense marking fluid, wherein the first printhead is arranged in line with the second printhead. The controller may cause the printing system to enter a first print mode, wherein in the first print mode, there are a plurality of passes of a printing mechanism where pre-treatment fluid and/or marking fluid is applied to the recorded medium, and wherein a first of the plurality of passes is to be of the pre-treatment fluid from the first printhead without the second printhead dispensing marking fluid.
Patent WO-2021041946-A1 (WO)
Title: Random access procedure modification in internet of things communication
Inventor: SURUVU NAGA SEKHAR
IPC: H04W72/04
Filed: 2020-08-28
Abstract: Methods, systems, and devices for wireless communication are described. A user equipment (UE) may receive configuration information from a base station. The UE may determine, based at least in part on the configuration information, a number of subframes available within a random access response (RAR) time window for downlink control channel communications. The UE may modify a random access procedure based on the determined number of subframes available within the RAR time window for the downlink control channel communications. In one example, modifying the random access procedure may include skipping a decoding attempt using a decoding hypothesis. In another example, modifying the random access procedure may include aborting the random access procedure.