baber/WOPTO huggingface dataset:
Patent EA-019099-B1 (EA)
Title: Method for targeted transgene delivery in myocardium of a patient with myocardial ischemia
Inventor: HAMMOND KIRK H
IPC: A61K35/76
Filed: 1999-02-09
Abstract: The invention relates to a method for targeted transgene delivery in a myocardium of a patient with myocardial ischemia used for gene therapy of a disease in vivo and comprising direct injection of the vector into arteries supplying myocardium, preferably in combination with a vasoactive agent that is infused into the artery prior to or coincident with the delivery of the vector.
Patent EA-008824-B1 (EA)
Title: Clostridium botulinum c3 exotransferase compositions and methods for treating tumor spreading
Inventor: MCKERRACHER LISA
IPC: A61K38/17
Filed: 2004-09-29
Abstract: Pharmaceutical compositions, each consisting of a cell-permeable fusion protein conjugate of a polypeptidic cell-membrane transport moiety and a Clostridium botulinum C3 exotransferase unit, or a functional analog thereof, are provided. The compositions are useful to prevent or inhibit uncontrolled proliferation, spreading, and migration of a metastatic neoplastic cell of a cancer in a mammal. The compositions can each effect or arrest combination of two or more of tumor cell proliferation, migration, angiogenesis, and metalloproteinase secretion.
Patent EA-011047-B1 (EA)
Title: Transfer pyramid for manufacturing medical-preventive preparations
Inventor: GLUSHKOV ANDREY VASILIEVICH
IPC: A61J3/00
Filed: 2007-05-04
Abstract: Invention relates to devices for preparing medical-prophylactic agents enhancing vital capacity of different flora and fauna species and can be used in medicine, veterinary and agriculture.A transfer-pyramid for preparing medical-prophylactic agents (7) comprises at least one capacity (6) with a carrier or preparation (7) being treated housed therein, has a base (1) and a hollow pyramidal part (2) adapted for raising. Sources of alpha-rhythms and/or other energo-informative effect (4) on the carriers or preparation (7) being treated embodied as acoustic loudspeakers (12) for transfer medical properties.The capacities (6) with carriers or preparations (7) are arranged on a support (8) mounted on the pyramid base (1), wherein a table top (9) of the support (8) is parallel to the pyramid base (1).Water, alcohol, salt, sugar, minerals, creams etc. or allopathic, homeopathic, naturopathic preparations in solid or liquid state are used as the carrier (7) being treated.CD or DVD discs are used as the alpha-rhythms carriers or other energo-informative effect, and a player or PC (13) are used as a replaying device.The pyramid can be embodied with an obtuse or acute angle4 at its vertex, and the base is shaped as a square or a rectangular, the pyramid faces (3) and the base (1) are fabricated from plastic, wood, ferrous or non-ferrous metals, glass, glass-fiber materials, impregnated fabrics etc.The support (8) and the capacities (6) for carriers or preparations (7) are fabricated of the same material used for the pyramid faces.The achieved inventive result is characterized in that the preparations produced in the transfer pyramid exhibit sufficiently effective medical and prophylactic properties, enhancing organism resistance to stress, toxic and vibration effects, and also to metabolic disorders which has been proved by studies carried out in March 2004 through March 2006 at the Department of Histology, Kirov State Medical Academy.
Patent EA-016022-B1 (EA)
Title: Isolated mammalian anti-il-12 antibody and method for altering the activity thereof
Inventor: GILES-KOMAR JILL
IPC: A61K39/395
Filed: 2005-12-20
Abstract: A mammalian anti-IL-12 antibody is proposed that binds to a portion of the IL-12 protein corresponding to at least one amino acid residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the SEQ ID NO:9 amino acid sequence. The antibody have applications in diagnostic and/or therapeutic compositions, methods and devices.
Patent EA-018840-B1 (EA)
Title: A recombinant host cell for the production of a compound of interest
Inventor: SAGT CORNELIS MARIA JACOBUS
IPC: C12N1/14
Filed: 2008-02-12
Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The present invention also relates to isolated fungal promoter DNA sequences, to DNA constructs, vectors, and fungal host cells comprising these promoters in operative association with coding sequences encoding a compound of interest. The present invention also relates to methods for expressing a gene of interest and/or producing compounds of interest using a promoter according to the invention.
Patent EA-019564-B1 (EA)
Title: Method and apparatus for determining gas pressure in a gas/liquid flow
Inventor: ATKINSON IAN
IPC: G01F1/34
Filed: 2010-05-26
Abstract: An apparatus and method are provided for determining the static gas pressure in a gas/liquid flow. The apparatus and method may be non-invasive relative to the flow to be analyzed. The apparatus and method may include swirling a multiphase flow so that the flow is separated into a gas core and a liquid outer layer, measuring flow parameters, including the liquid layer tangential velocity, the liquid holdup, and the static pressure of the flow at the wall of conduit, and determining the static gas pressure in the gas core from the measured flow parameters.
Patent EA-018486-B1 (EA)
Title: Mixture of furfural and 5-(alkoxymethyl)furfural derivatives from sugars and alcohols
Inventor: GRUTER GERARDUS JOHANNES MARIA
IPC: C07D307/46
Filed: 2008-09-05
Abstract: Accordingly, the current invention provides a method for the manufacture of a mixture of a furfural and a 5-(alkoxymethyl)furfural derivative by reacting a C5 and C6 sugar-containing starting material with an alcohol in the presence of an acid catalyst, followed by the hydrogenation and/or etherification of the mixture of furfural and 5-(alkoxymethyl)furfural to convert the aldehyde function of both 5-(alkoxymethyl)furfural and furfural into an alkoxymethyl function or methyl function.
Patent EA-019358-B1 (EA)
Title: Allele and isotype-specific intervention on mhc class ii molecules associated with autoimmune diseases by means of peptides
Inventor: WEISSERT ROBERT
IPC: C07K7/06
Filed: 2008-12-03
Abstract: The present invention relates to a peptide for the treatment or prophylaxis of an autoimmune disease, a nucleic acid molecule coding for said peptide, a pharmaceutical composition comprising the peptide and/or the nucleic acid molecule, and to a method for the treatment and/or prophylaxis of an autoimmune disease.
Patent EA-019374-B1 (EA)
Title: Telmisartan composition and process for manufacturing same
Inventor: PROKOPOVA ALENA
IPC: A61K9/20
Filed: 2009-07-28
Abstract: A composition containing the active substance telmisartan, which consists of granules of a telmisartan mixture, in which there is the active substance in the form of alkali salts, further contained is an organic or inorganic base selected from meglumine, sodium or potassium hydroxide, or a mixture of said bases, a binder, most preferably polyvinylpyrrolidone, sorbitol, and optionally other auxiliary substances; the composition further containing, outside the granules, particles of sorbitol, and optionally of other auxiliary substance, the size of 99% by weight of all particles of the telmisartan mixture being smaller than 1.0 mm and the size of 95% by weight of all particles of sorbitol contained in the composition inside as well as outside the granules of the telmisartan mixture being within the range of 0 to 0.250 mm.
Patent EA-024755-B1 (EA)
Title: Biosynthetic proline/alanine random coil polypeptides and their uses
Inventor: SKERRA ARNE
IPC: C07K7/00
Filed: 2011-05-20
Abstract: The present invention relates to a biosynthetic random coil polypeptide or a biosynthetic random coil polypeptide segment or biosynthetic conjugate, wherein said biosynthetic random coil polypeptide, said biosynthetic random coil polypeptide segment or said biosynthetic conjugate comprises an amino acid sequence consisting solely of proline and alanine amino acid residues, wherein said amino acid sequence consists of at least about 50 proline (Pro) and alanine (Ala) amino acid residues. Said at least about 50 proline (Pro) and alanine (Ala) amino acid residues may be (a) constituent(s) of a heterologous polypeptide or an heterologous polypeptide construct. Also uses and methods of use of these biosynthetic random coil polypeptides or polypeptide segments or said conjugates are described. The uses may, inter alia, comprise medical uses, diagnostic uses or uses in the food industry as well as other industrial applications, like in the paper industry, in oil recovery, etc. In particular, a drug conjugate is provided that comprises (i) a biosynthetic random coil polypeptide or polypeptide segment comprising an amino acid sequence consisting solely of proline and alanine amino acid residues, wherein said amino acid sequence consists of at least 50 proline (Pro) and alanine (Ala) amino acid residues, and (ii) a drug selected from the group consisting of (a) a biologically active protein or a polypeptide that comprises or that is an amino acid sequence that has or mediates a biological activity and (b) a small molecule drug. Furthermore, nucleic acid molecules encoding the biosynthetic random coil polypeptide or polypeptide segment and/or the biologically active, heterologous proteins as well as vectors and cells comprising said nucleic acid molecules are disclosed. In addition, the present invention provides compositions comprising the compounds of the invention as well as specific uses of the random coil polypeptide or polypeptide segment, the biologically active proteins, the drug conjugates or the nucleic acid molecules, vectors and cells of the invention. Also methods of producing and/or obtaining the inventive biosynthetic random coil polypeptides or polypeptide segments as well as of producing and/or obtaining the inventive biologically active, heterologous proteins, and/or polypeptide constructs or conjugates, like drug conjugates are provided.
Patent EA-026420-B1 (EA)
Title: Connector system for medical fluid administration
Inventor: PAZIK KAROL
IPC: A61M39/20
Filed: 2011-04-07
Abstract: A connector system for medical fluid administration has a female connection member, which can act as an access port for a container of medical fluid, and a male connection member, for accessing the container of medical fluid. The female connection member defines a sheath for receiving a portion of the male connection member and this sheath is spanned at one end by a septum, which acts to close the container of medical fluid. A lumen is defined through the male connection member to allow passage of fluid therethrough. The septum has a central region and a peripheral region, the central region being of substantially greater thickness than the peripheral region. The male connection member comprises means for rupturing the peripheral region of the septum when it is received in the female connection member to form a connection.
Patent EA-022367-B1 (EA)
Title: Spacer for a vacuum glazing panel, and corresponding vacuum glazing panel and production method
Inventor: CALIARO SEBASTIEN
IPC: E06B3/663
Filed: 2011-05-17
Abstract: The invention relates to a spacer (8) to be sandwiched between first and second glass sheets (5) of a vacuum glazing panel, such as to maintain a first space between the glass sheets, which space forms a first cavity (4) under a vacuum of less than 1 mbar, a sealing joint (1) being positioned on the periphery of the glass sheets enclosing the first cavity. According to the invention, one such spacer (8) comprises cold-worked austenitic stainless steel.
Patent EA-024379-B1 (EA)
Title: Process for producing aromatic polycondensation reaction polycarbonate, and polymerizer
Inventor: HACHIYA HIROSHI
IPC: C08G64/20
Filed: 2011-10-14
Abstract: A method for producing a condensation polymerization reaction polymer, comprising a guide polymerization step in which a molten prepolymer is supplied to the top edge of wire guides in a polymerization reactor for production of a condensation polymerization reaction polymer, and is allowed to drop while contacting the wire guides in conducting polymerization of the molten prepolymer and to obtain the condensation polymerization reaction polymer, the wire guides comprise a vertical wire group consisting of a plurality of vertical wires extending in the vertical direction, which are mutually spaced in alignment at an arrangement pitch L1 (mm). In the guide polymerization step, the molten prepolymer supplied from the top edge of the wire guides aggregates so that a molten prepolymer mass is formed on the vertical wire, and a molten prepolymer mass is formed wherein, the width of the molten prepolymer mass measured in an alignment direction of the vertical wires at a position 200 mm below the top edge being represented as L2 (mm), the width L2 (mm) of at least a portion of the molten prepolymer mass satisfies the relationship with L1 (mm) as defined by inequality (1) L1<L2.
Patent EA-028459-B1 (EA)
Title: Synergistic herbal composition for prevention and treatment of diabetic retinopathy and cataract
Inventor: BAHRI DEEPAK
IPC: A61P27/12
Filed: 2012-11-02
Abstract: The invention relates to a synergistic herbal composition for preventing and curing secondary complications arising from diabetes mellitus such as diabetic retinopathy and cataract and a process for the preparation of the same in pharmaceutically acceptable dosage forms and the use thereof in treating diabetic retinopathy and cataract.
Patent EA-028555-B1 (EA)
Title: Food composition comprising vitamin k and saturated fat and its use
Inventor: ZWIJSEN RENATE MARIE LOUISE
IPC: A23L33/15
Filed: 2013-02-15
Abstract: Food composition comprising fat and vitamin K, wherein the fat comprises at least 36% saturated fatty acids, and wherein the vitamin K is in the form MK-7 in an amount of at least 0.1 mcg MK-7 per daily intake. The composition preferably further comprises milk or milk derived ingredients, calcium, magnesium, potassium, polyunsaturated fatty acids and/or vitamin D. Preferably, the composition is a dairy composition such as a yogurt, milk drink, cheese, cream, etc.
Patent EA-031776-B1 (EA)
Title: Method of processing cellulosic and/or lignocellulosic biomass material
Inventor: MEDOFF MARSHALL
IPC: B01J19/08
Filed: 2014-03-07
Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, equipment, systems and methods are described that can be used to treat feedstock materials, such as cellulosic and/or lignocellulosic materials, in a vault in which hazardous gases are removed, destroyed and/or converted. The treatments are efficient and can reduce the recalcitrance of the lignocellulosic material so that it is easier to produce an intermediate or product, e.g., sugars, alcohols, sugar alcohols and energy, from the lignocellulosic material.
Patent EA-030426-B1 (EA)
Title: 6,7-DIHYDROPYRAZOLO[1,5-α]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF mGluR2 RECEPTORS
Inventor: VAN GOOL MICHIEL LUC MARIA
IPC: C07D487/04
Filed: 2014-06-03
Abstract: The present invention relates to novel 6,7-dihydropyrazolo[1,5-α]pyrazin-4(5H)-one derivatives of Formula (I)as negative allosteric modulators (NAMs) of metabotropic glutamate receptors subtype 2 ("mGluR2"). The present invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved, especially CNS disorders.
Patent EA-036313-B1 (EA)
Title: Surgical tool with an aseptic power module that enters a specific operating state based on the type of handpiece to which the module is attached
Inventor: MISTRY VIREN P
IPC: A61B90/90
Filed: 2015-10-29
Abstract: Described herein is a surgical tool that includes a sterilizable handpiece that receives an aseptic power module. The handpiece includes a data tag that contains data identifying the type of handpiece. The power module includes a reader that reads the data from the data tag. Based on the type of handpiece the power module selectively actuates the power generating unit internal to the power module. Specifically, the power generating unit is actuated to output energy having the appropriate characteristics for the type of handpiece to which the power module is attached. In many versions of the invention, the data tag is mounted to the latch integral with the handpiece. The power module also interprets the receipt of the data from the handpiece as an indication that the power module is properly latched into the handpiece.
Patent EA-038668-B1 (EA)
Title: Distributing head for a pneumatically operating distributing machine
Inventor: SCHWAMM VICTOR
Filed: 2018-08-03
Abstract: The invention relates to a distributing head (7) for a pneumatically operating distributing machine (1) for seed, fertilizer and the like. The distributing head (7) is connected to a reservoir (3). Circularly symmetrically distributed outlets are arranged on the distributing head (7), which outlets are adjoined by distribution lines (10), which lead to discharge devices (6) for the material to be distributed. Air-permeable blocking elements (11) that interact with the outlets (9) are to be arranged in the distributing head (7) in order to block off one or more of the distribution lines (10). In order to easily make it possible that, in the case of separate outlets of distribution lines (10) that can be blocked off by means of individual blocking elements (11), conveying air flow can escape from the distributing head (7) via the blocked-off distribution lines (10), according to the invention, the blocking elements (11) are designed as blocking wedges (12) having a base part (13) to be inserted into the associated outlet (9) to be blocked, and the blocking wedges (12) each have, above the base part (13) to be inserted into the associated outlet (9), at least one through-opening (14) ending in the region of the lower end of the base part (13).
Patent ES-2181542-B1 (ES)
Title: Procedimiento para la adaptacion de una instalacion formada por un horno rotativo tubular y un refrigerador planetario.
Inventor: BOURDON ERIC
IPC: F27B7/38
Filed: 2000-07-17
Granted: 2003-12-16
Abstract: Procedimiento para la adaptación de una instalación formada por un horno rotativo tubular y un refrigerador planetario. La invención se refiere a un procedimiento para la adaptación de un horno rotativo tubular con refrigerador planetario por corte del refrigerador planetario, desplazando la penúltima estación de rodillos de rodadura hasta que la carga de apoyo en la antepenúltima estación de rodillos de rodadura se mantenga dentro de la gama de carga normal.
Patent ES-2169678-B1 (ES)
Title: Procedimiento de preparacion de yogur con valeriana officinalis.
Inventor: ANEIROS DIAZ SILVIA TERESA
IPC: A23C9/13
Filed: 2000-08-02
Granted: 2003-11-01
Abstract: Procedimiento de preparación de yogur con Valeriana officinalis. Por adición de 10/12 gotas por yogur de extracto de Valeriana después de la pasteurización. El yogur así preparado tiene propiedades sedantes suaves características de esta planta.
Patent ES-2200621-B1 (ES)
Title: Columna de longitud graduable, asi como cojinete axial, y procedimiento de montaje para columna de longitud graduable de esta clase.
Inventor: SAUER RAINER
IPC: F16C17/04
Filed: 2001-02-09
Granted: 2005-05-01
Abstract: Columna de longitud graduable así como cojinete axial, y procedimiento de montaje para una columna de longitud graduable de esta clase. La columna está destinada para sillas o similares y comprende un tubo vertical con un eje longitudinal (A) y con una unidad de cilindro y émbolo. Un extremo longitudinal de esta unidad está enclavado en la dirección del eje por medio de un cojinete axial (22) en una placa de base (12a) del tubo vertical. Para ello, el cojinete axial (22) está unido fijamente al extremo longitudinal de la unidad de cilindro y émbolo en la dirección del eje (A). Además, el cojinete axial (22) tiene por lo menos dos brazos de enclavamiento (42), mediante los cuales puede ser enclavado en la placa de base (12a) del tubo vertical, así como un perno de sujeción (44) que, al realizarse la unión fija en el eje entre el cojinete axial (22) y el fondo (12a) del tubo vertical, puede ser introducido por la unidad de cilindro y émbolo entre los brazos de enclavamiento (42) y de este modo asegura el enclavamiento.
Patent ES-2180447-B1 (ES)
Title: Sistema y procedimiento para la separacion de particulas por medios opticos.
Inventor: GARCIA-TEJEDOR PEREZ JAVIER
IPC: B07C5/342
Filed: 2001-07-05
Granted: 2004-04-16
Abstract: Sistema y procedimiento para la separación de partículas por métodos ópticos. El sistema comprende un equipo de iluminación indirecta, una estación de captación de imágenes lineal, un equipo de control que recibe las imágenes captadas por dicha estación de captación de imágenes lineal y las somete a un tratamiento informático para identificar las partículas a separar, y un equipo de extracción por succión de las partículas a separar. El procedimiento comprende la identificación de las partículas a separar, mediante métodos ópticos, y su extracción individualizada por succión. De aplicación en la separación de partículas contenidas en un material que contiene un material base y partículas a separar, por ejemplo, residuos que contienen un producto a reciclar e impurezas.
Patent ES-2214122-B1 (ES)
Title: Sensor de microflujo bidireccional.
Inventor: ABARCA ALVAREZ ANTONIO
IPC: G01F1/68
Filed: 2002-12-20
Granted: 2005-11-01
Abstract: Sensor de microflujo bidireccional. Está estructurado a partir de un cuerpo base o sustrato cerámico (1), al que se asocian 16 patillas (6) distribuidas en dos alineaciones de manera que dicho cuerpo base adopta la configuración estándar de un circuito integrado con tal número de patillas, estableciéndose sobre el sustrato cerámico (1), además, una pareja de estructuras de silicio NPN (2) y (3), y entre ellas una estructura calefactora (4-5), elementos que utilizan ocho de las patillas o terminales de conexión (6) anteriormente citados, resultando las restantes inoperantes. Una pareja de tubos (15) y (16) se sitúan en alineación longitudinal a ambos lados del conjunto constituido por las estructuras NPN y la estructura calefactora, cerrada mediante una carcasa (19) para intercalación del dispositivo en el conducto en el que se va a realizar la medición, y es posible detectar la dirección de circulación del gas en función del gradiente térmico entre una y otra estructura NPN.
Patent ES-2259263-B1 (ES)
Title: Dispositivo para hacer nudos de corbata.
Inventor: DEL BARRIO GORBE IGNACIO
IPC: A41D25/08
Filed: 2004-09-30
Granted: 2007-10-01
Abstract: Dispositivo para hacer nudos de corbata. La presente invención se caracteriza por tratarse de un dispositivo para hacer nudos de corbata, del cual pueden beneficiarse tanto aquellas personas que no saben hacerse por si solas el nudo de la corbata cómo aquellas otras que aún sabiendo hacerlo, buscan las características de dicho dispositivo. La solución técnica que aporta el dispositivo es que se basa en la reproducción de los movimientos originales necesarios para generar un nudo de corbata, movimientos que son indicados de forma clara e intuitiva mediante una serie de orificios practicados en el dispositivos, facilitando este proceso y definiendo la secuencia de los pasos a seguir utilizando numeraciones, colores y geometrías cómo apreciamos en la descripción de los dibujos.