baber/WOPTO huggingface dataset:
Patent CR-20110080-A (CR)
Title: 4-fenil-1h-pirazoles insecticidas
Inventor: WERNER STEFAN
IPC: A01N43/54
Filed: 2011-02-11
Abstract: La presente invención se refiere a nuevos 4-fenil-1H-pirazoles y a su uso como insecticidas y/o parasiticidas así como a procedimientos para su preparación y agentes que contienen tales fenilpirazoles.
Patent CR-20110083-A (CR)
Title: Aparato y método para unión de capas así como producto de múltiples capas
Inventor: SAUTER JÜRGEN
IPC: B31F1/07
Filed: 2011-02-14
Abstract: Aparato para unir por lo menos dos capas (13, 14) de una malla fibrosa, que comprende un primer rodillo (10) que tiene una periferia externa, por lo menos una protuberancia de relieve que se provee en la periferia externa; y un segundo rodillo (20) que tiene una periferia externa y que es elástica por lo menos en una dirección radial.
Patent CR-20110512-A (CR)
Title: Iluminador de guía de luz anular y escáner óptico
Inventor: MILAN VASIC
IPC: G02B6/00
Filed: 2011-09-29
Abstract: El iluminador de guía de luz anular divulgado es operable para guiar luz desde su superficie de entrada hasta su superficie de salida para iluminar una zona en su extremo distal, y comprende una cavidad interior en forma de cono truncado cuya base se abra en dicho extremo distal.
Patent CR-20140224-A (CR)
Title: Inmunoligantes biespecificos dirigidos contra tnf e il-17 referencia cruzada a solicitudes relacionadas
Inventor: HSIEH CHUNG-MING
IPC: C07K16/46
Filed: 2014-05-14
Abstract: Se proporcionan proteínas de unión multiespecíficas y multivalentes diseñadas, métodos de fabricación, y específicamente sus usos en la prevención, diagnóstico y/o tratamiento de la enfermedad.
Patent CR-20150637-A (CR)
Title: Tratamiento de enfermedades miopaticas y neurodegenerativas por agregación de proteina mediante administración parenteral
Inventor: MEGIDDO DALIA
IPC: A61P25/28
Filed: 2015-12-04
Abstract: Se divulga un método para tratar una enfermedad asociada con agregación anormal de proteína que comprende formulaciones farmacéuticas de administración parenteral que comprende trehalosa. También se divulga una formulación farmacéutica acuosa inyectable que comprende una cantidad terapéuticamente efectiva de trehalosa.
Patent CR-20170354-A (CR)
Title: Derivados de tetrahidropiranil benzamida
Inventor: ZHOU JINGYE
IPC: C07D405/14
Filed: 2016-02-19
Abstract: La presente invención se refiere a compuestos de la Fórmula siguiente: en donde R, R1-R3 son como se describen en la presente; métodos para tratar pacientes por diabetes usando los compuestos, y procesos para preparar los compuestos.
Patent CR-20180105-A (CR)
Title: Diacuerpos monovalentes biespecificos que son capaces de unirse a b7-h3 y cd3, y usos de los mismos
Inventor: BONVINI EZIO
IPC: C07K16/30
Filed: 2016-08-12
Abstract: La presente invención se dirige a diacuerpos monovalentes biespecíficos DE B7-H3 x CD3, y particularmente, a diacuerpos Fc monovalentes biespecíficos de B7-H3 x CD3, que son capaces de unirse de forma simultánea a B7-H3 y CD3. La invención también se dirige a composiciones farmacéuticas que contienen tales diacuerpos Fc monovalentes biespecíficos. La invención se dirige adicionalmente a métodos para el uso de tales diacuerpos en el tratamiento de cáncer y otras enfermedades y padecimientos
Patent CR-20180409-A (CR)
Title: Repelente de insectos
Inventor: RICHMAN DINA L ;
IPC: A01P17/00
Filed: 2017-02-28
Abstract: En un aspecto, la presente invención se relaciona con composiciones repelentes de plagas que comprenden un ácido graso y un éster de antranilato. En otro aspecto, la presente invención se relaciona con un método para repeler plagas empleando dicha composición. En otro aspecto, la presente invención se relaciona con productos formulados a partir de dicha composición.
Patent CR-20210319-A (CR)
Title: Anti-pd-1 antibodies and methods of treatment
Inventor: ALI KHALED M K Z
IPC: C07K16/28
Filed: 2019-01-11
Abstract: Provided herein are PD-1 antigen-binding proteins and related nucleic acids, vectors, host cells, kits and pharmaceutical compositions. Methods of making PD-1 antigen-binding proteins and methods of treating a subject are further provided.
Patent CR-20210331-A (CR)
Title: Cytotoxicity-inducing therapeutic agent
Inventor: NARITA ATSUSHI
IPC: C12P21/08
Filed: 2015-09-25
Abstract: A novel multispecific antigen-binding molecule, which comprises a domain containing an antibody variable region having an activity of binding to glypican 3 and a domain containing an antibody variable region having an activity to bind to a T cell receptor complex and retains excellent cytotoxic activity and high safety, was found. The molecule according to the present invention exhibits potent cytotoxic activity on cells and tissues expressing glypican 3 and, therefore, enables the production of new pharmaceutical compositions for treating or preventing various kinds of cancers.
Patent EC-SP088444-A (EC)
Title: Bloque de cilindro para compresor de gas integral y motor de combustión interna
Inventor: ATKINSON MICHAEL KENNETH
IPC: F04B17/00
Filed: 2008-05-09
Abstract: Un bloque de cilindro para un compresor de gas integral y motor de combustión interna. El bloque de cilindro tiene un banco de cilindros de compresor y un banco de cilindros de motor, tal como en una configuración en V. las aberturas del tren de válvula se fabrican en el bloque del cilindro adyacente a los cilindros de motor de tal manera que los componentes del tren de válvula del motor, tal como los vástagos de empuje, pueden estar dispuestos allí. No se construyen aberturas del tren de válvulas dentro del bloque del cilindro adyacente a los cilindros del compresor; el bloque se deja sólido. También se describe un compresor que utiliza el bloque del cilindro
Patent EC-SP088676-A (EC)
Title: Pirazolquinolonas como potentes inhibidores de parp
Inventor: PENNING THOMAS D
IPC: A61K31/438
Filed: 2008-08-12
Abstract: Compuestos de la fórmula (I) que inhiben la enzima PARP y son de utilidad para el tratamiento de una enfermedad o un trastorno asociado con PARP. También se divulgan composiciones farmacéuticas que comprenden a los compuestos de la fórmula (I), métodos de tratamiento que comprenden a los compuestos de la fórmula (I) y métodos para inhibir la enzima PARP que comprende a los compuestos de la fórmula (I). Fórmula (I)
Patent FI-20002169-A (FI)
Inventor: NIEMI ASKO
IPC: G01F/
Filed: 2000-10-02
Abstract: The invention concerns an arrangement and a method for measuring the quantity of a fluid in an uneven flow. The arrangement comprises a housing 1, in which is arranged an inlet connection 7 and an outlet connection 8 for the liquid being measured. The inside of the housing 1 is divided by a midplane 6 into an upper inlet chamber 20, where said inlet connection 7 emerges, and a lower outlet chamber 21, where the outlet connection 8 emerges. In the inlet chamber 20, by means of partition walls 11 arranged on the upper side of the midplane 6, which are essentially lower than the height of the inlet chamber, there are formed two compartments A, B, C, both of which A, B, C have an opening element 9, through which the flowing liquid flows through the compartments A, B, C of the inlet chamber 20 a certain quantity per unit of time, l/min. Each compartment A, B, C has a sensor 10 for this, by means of which the dwell time of the liquid in each chamber A, B, C can be detected. For this, the arrangement has elements for determining the total quantity of liquid flowing through the arrangement on the basis of the data put out by the sensors as to the dwell time of the liquid and a known flow volume per unit of time through the opening elements 9. <IMAGE>
Patent GB-1050290-A (GB)
IPC: F16K35/02
Abstract: 1,050,290. Pipe couplings. SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ N.V. Aug. 21, 1964 [Aug. 23, 1963], No. 34300/64. Heading F2G. A coupling part 1 has a flange 8 and includes a sealing ring 11 which forms a gas-tight connection with a valve-operating member 20 in a coupling part 2, and a valve 13 capable of closure by a spring 12 and/or gas pressure. Upon interconnection of the parts by sliding the flange 8 transversely into the recess 32 of the part 2, rotation of the cam 27 by handle 28 to a first position causes the member 20 to move axially into the part 1 thereby preventing disconnection of the parts, and further rotation of the cam causes the member 20 to then open the valve 13; gas from a container flows to radial pipe-connecting portion 24 which extends through a slot 23 in the wall of part 2. The sealing ring may, alternatively. be secured to the member 20.
Patent GB-1051746-A (GB)
IPC: C07D501/34
Abstract: 1,051,746. Cephalosporin C derivatives. CIBA Ltd. Aug. 17, 1964 [Aug. 20, 1963], No. 33570/64. Heading C2A. The invention relates to derivatives of cephalosporin C of formula in which R is alkenyl, and physiologically tolerable salts thereof. Specified salts are the sodium, potassium, calcium, triethylamine, N - ethyl - piperidine, dibenzylethylenediamine and procaine salts. The compounds are obtained by reacting cephalosporin C with an isothiocyanic acid ester of formula to produce the thiocarbamic acid derivative, followed by ring-closure in an acidic medium to form the thiohydantoin. In the example, cephalosporin C is reacted with allyl isothiocyanate in aqueous acetone to produce N- (allyl-thiocarbamyl)-cephalosporin C, which is isolated. This compound is converted to 7- [4 - (1 - allyl - 2 - thiono - 5 - oxo - imidazolidin- 4-yl) - butyryl] - amino - cephalosporanic acid by treatment with glacial acetic acid. Pharmaceutical compositions for human and animal use comprise the above thiohydantoin and thiocarbamyl derivatives of cephalosporin C and a carrier. The carrier may be an animal feedstuff. Formulations may be for oral, parenteral or topical use. The active material may be incorporated in disinfectants.
Patent GB-1052024-A (GB)
IPC: B65B21/24
Abstract: 1,052,024. Packaging. VEREENIGDE GLASFABRIEKEN (UNITED GLASSWORKS) N.V. Aug. 13, 1963 [Aug.13, 1962]. No. 31992/63. Heading B8C. A method of packing parallel-sided articles of rounded cross-section in a rectangular parallelapipedic package comprises placing the articles 3 in rows to form a block, inserting the block into a tight fitting flexible plastics envelope 4 which has one or both of its ends open, folding the ends inwardly and heatsealing in position. In one embodiment bottles are fed from a trough 1 by a piston 30 into the tube 4 which has previously been positioned over the end of the trough by a reciprocating carrier 25 which retains the tube in stretched position by suction and grips it with members 29. The block is placed in the central part of a trough section table 6, which rises to surround the tube on three sides after the carrier has withdrawn. The length of tube is severed by a knife 23. The bottles may be finally positioned by the end 31 of the table folding upwardly to form an abutment, the same movement folding up an end wall of the tube. The equivalent other end 11 is folded upwardly, the end of the package then being as in Fig. 4, the length of the tube being such as to provide a strip 35 which lies against a flap 13. End flaps 9, 10 are swung inwardly resulting in the form of Fig. 5 (not shown), which allows the strip 35 to be heat-sealed. In alternative sealing methods, wings 14, 15, Fig. 6 (not shown), are folded inwardly under tension and sealed against a temporarily inserted bearing pad 19 forming a carrying handle or they may be cut off and apertured to form carrying lugs. The bottles may be arranged in the package horizontally. The package can be formed by placing plastics foil in a trough (Fig. 8, not shown) and arranging the bottles inside before sealing the foil under tension on the top to tube it about the bottles.
Patent GB-1052648-A (GB)
IPC: G11C11/06
Abstract: 1,052,648. Magnetic storage apparatus. INTERNATIONAL BUSINESS MACHINES CORPORATION. May 19, 1965 [June 23, 1964], No. 21141/65. Heading H3B. In a chain store matrix, each of a plurality of word conductor strips coated with magnetic material and having apertures defining bit storage locations is sandwiched between a pair of return conductor plates 126, 128 whereby to confine word drive switching flux to the region between the return conductor plates, Fig. 5 (not shown). As shown in Fig. 3, each pair of return conductor plates sandwiches two word conductors and is separated from adjacent plates by insulator sheets 124. Larger return conductor plates may be used but would increase the capacitance seen by the gates with a consequent increase in switching time. Read-out from bit storage location 110 is accomplished by energizing word driver 152 and applying an input to gate 166 to remove the back bias from diode 155 whereupon an output pulse 52 or 54, Fig. 2 (not shown), of polarity dependent on the information read, is induced in bit-sense conductor 142. For writing in, bit driver 192 is energized to deliver a bit drive pulse subsequent to, but overlapping with, the word drive pulse and of polarity dependent on the information to be written in. Bit-sense conductors 140, 142 are connected to opposite ends of a centre tapped primary winding of transformer 186 whereby noise common to the two conductors is cancelled.
Patent GB-1053262-A (GB)
IPC: F21V11/16
Abstract: 1,053,262. Vehicle headlamps. E. THOMPSON. Nov. 25, 1965 [Dec. 17, 1964], No. 51463/64. Heading F4R. A funnel-shaped cowl 1 having a flat top 2 arranged to be substantially horizontal is attached to the front of the lamp holder, e.g. to the reflector, the cross-section of the cowl increasing towards the front end and the bottom being inclined downwards, e.g. at 5 or 10 degrees. The sides are also inclined outwards at the same angle. The inner surfaces of the bottom and sides of the cowl are non-reflective except over a small area at the inner end. The front of the cowl may be closed by a diffusing screen 5. The cowl may be used with a single or double lamp. The sides and bottom may be curved.
Patent GB-1053733-A (GB)
IPC: B65G49/04
Abstract: 1,053,733. Endless conveyers. TECHNICAL & SCIENTIFIC SERVICES Ltd. Aug. 1, 1963 [Aug. 3, 1962], No. 29937/62. Heading B8A. [Also in Division C7] In a plating apparatus comprising baths arranged to define a closed circuit treatment path and a guide rail following that path and adapted to support carriers for articles to be treated as they are moved along the path, the guide rail being formed to include section capable of individual vertical displacement s that when the movable sections are raised they define a continuous element extending along the treatment path and when they are lowered they interrupt the continuous element, the carriers are arms 12 pivotally carried by a travelling element, such as endless roller chain 18, for movement along the treatment path, e.g. by means of chain guide 27, and extending transversely of the guide rail 22 and the baths 10. The vertical movement of the movable sections of rail 22 is effected by pneumatic cylinders 25 which are exhausted directly or indirectly into the baths to effect agitation and are so operated when it is desired to lower articles to be treated into a desired bath, the chain being moved intermittently and arrested during vertical movement of the carrier arms and whenever a carrier arrives at a single treatment bath or at the end of a long one. As described the plating is effected electrolytically, the carrier arms supporting racks 20 bearing the articles to be plated and being connected into an electrical plating circuit at least in their lowered position. The baths comprise copper, nickel, chromium, and brass plating solutions separated by acid treatment and rinsing tanks. Sections of the guide rail located at loading and unloading stations are fixed.
Patent GB-1226900-A (GB)
IPC: G01S13/95
Filed: 1969-07-21
Abstract: 1,226,900. Pulse radar; gain control arrangements. BENDIX CORP. 21 July, 1969 [6 Aug., 1968], No. 36577/69. Headings H3Q and H4D. In a radar the echo signals in excess of a predetermined level are integrated with respect to time and the receiver gain is increased as a function of the integrated signals. The invention is applied to a known airborne weather radar which incorporates a sector P.P.I. display having bearing scale markers and cathode-ray range rings, a "contour" circuit which blanks a receiver video amplifier whenever the video level exceeds a threshold so that storm areas are shown as dark cells surrounded by a bright contour, and a swept gain circuit. In the embodiment the latter includes transistor 41 momentarily rendered conductive by a radar trigger pulse applied to its base, the conduction causes capacitor 42 to charge to a voltage determined by potentiometer 40; when the trigger pulse disappears capacitor 42 discharges through resistor 43, diode 44 and resistor 45. Diode 44 prevents retrace blanking pulses applied to amplifier 26 from affecting the charge on capacitor 42. The modification introduced by the embodiment of the invention includes transistor 48 biased to be normally non-conductive by a voltage from potentiometer 49. Echo, video signals of an amplitude sufficient to overcome the threshold set by potentiometer 49 cause transistor 48 to conduct by an amount dependent on the excess video amplitude, thereby causing capacitor 42 to discharge more rapidly, Fig. 6 (not shown).
Patent GB-1226984-A (GB)
IPC: E04B1/343
Filed: 1968-06-25
Abstract: 1,226,984. Geometric design of collapsible buildings. GENERAL ELECTRIC CO. 25 June, 1968 [5 Sept., 1967], No. 30124/68. Heading E1A. A collapsible or hinged building structure consists of planar elements 3 of trapezoidal or isosceles triangular configuration arranged in two sets about the frustrum of a cone 2, the two sets being designated "positive" and "negative" as shown and arranged so that all of the "positive" elements adjoin only the "negative" elements and vice versa. The "positive" and "negative" elements differ from one another having regard to their angle of inclination with respect to the base of the cone 2 for details of which angles to-gether with other mathematical desiderata and preferred geometrical designs of buildings resulting therefrom the Specification and remaining drawings, (not shown), should be referred to.
Patent GB-1231150-A (GB)
IPC: C11D3/386
Filed: 1969-02-10
Abstract: 1,231,150. Detergents containing enzymes. TAKEDA YAKUHIN KOGYO K.K. 10 Feb., 1969 [8 Feb., 1968; 15 March, 1968], No. 7035/69. Heading C5D. [Also in Division C3] A detergent composition comprises an alkaline protease (see Division C3), a surfactant such as natural fatty acid soaps, alkyl sulphates, alkyl sulphonates, alkylaryl sulphonates, olefine sulphates, n-α-olefine sulphonates, tetrapropylbenzene sulphonates, n - alkylbenzene sulphonates, polyoxyethylene alkyl ethers, polyoxyethylene alkyl phenol ethers, polyhydric alcohol alkyl esters, polyoxyethylene alkyl esters or sugar esters. The compositions may also contain builders such as tri-polyphosphates, sulphates, carbonates or borates; fluorescent dyes; carboxymethyl cellulose, scents, perborates, sodium nitrilo triacetate, dimethyl lauryl aminoxide and tertiary amines. They may be kitchen detergents, laundry detergents or shampoos.
Patent GB-1233320-A (GB)
IPC: B65D90/62
Filed: 1969-09-24
Abstract: 1,233,320. Fastenings. A. S. MUSTADS FABRIKKER. 24 Sept., 1969 [24 Sept., 1968], No. 46971/69. Heading E2A. [Also in Division F4] A closing device for a closure member 3 pivotally mounted on a shaft 4 comprises a lever 6 keyed to the shaft and with a flexible portion 6 engaging the closure member and a second lever 8 also keyed to the shaft and extending radially therefrom, the second lever being connected to a rod 9 which is pivoted to a cam connected to a handle. The handle lies along the length of the rod and the handle and cam are moved through an opening 13 in a wall of the container to be closed to release the closure member. To secure the closure member in closed position, after pulling the handle and cam, they are pivoted so that the handle abuts the surface of the container wall the cam causing more effective closure. The closing device may be applied to a closure member for a furnace, silo or other container.
Patent GB-1234002-A (GB)
IPC: E06B9/74
Filed: 1969-03-28
Abstract: 1,234,002. Flexible door drive mechanism. R. L. KUSS & CO. Inc. 28 March, 1969 [16 Jan., 1969], No. 16334/69. Heading E2M. A flexible door 10 whose lower edge is wound on a roller 11 and whose upper edge is secured to the door lintel 12 is driven by means of an endless chain 14 engaging a drive sprocket 37 mounted on a tubular sleeve 20, journalled for rotation within bearings 18 and 19 suspended from a support 17, and having a pulley 23 connected to the drive shaft 27 of a motor 24 through a V-belt (25) and a pulley 26. Manual operation of the door may be effected by means of an axle 28 supported within the sleeve 20 by bearings 29 and 30 and having at one end a pulley 34 connected to the drive shaft 27 of the motor 24 through a V-belt (35) and a pulley (36) and at the other end a sprocket 32 for connection to a manually operated chain 33 outside the building. A second manual operating means may be provided inside the building in the form of a sprocket 32a and a chain.
Patent GB-1250455-A (GB)
IPC: E05B27/08
Filed: 1967-12-07
Abstract: 1,250,455. Locks. R. F. STURGEON. 6 Dec., 1968 [7 Dec., 1967], No. 55660/67. Heading E2A. A multiple axial pin tumbler lock comprises a cylindrical casing 10 housing a rotatable body part 11 having a screw threaded shaft 12 connected to a locking element and having axial bores 14 for driver pins 15 and a stationary collar 16 keyed to the casing has a surface adjacent a surface of the body part 11 and has bores 18 for spring loaded pins 19 which project into the bores, the rotatable body part being turned relatively to the collar by inserting a key which has fingers of predetermined lengths to depress the driver pins 15 and displace the pins from the bores 14 to allow the body part to rotate with respect to the collar. The spring loaded pins 19 may be of different lengths or alternatively pegs 21A or springs 20 limit the movement of the pins. The body part 11 is removable from the casing by releasing a circlip 22 in order to change the combination. In a modification to deter lock picking the spring loaded pins 119 have different lengths and are waisted. The rotatable body part 111 is detachably connected to the screw threaded shaft 112 by a blade 150 and is removable from the casing by aligning a slot in a disc 140 on the stationary part with a slot in a stationary sleeve member 143. The key is retainable in the rotatable part 111 by a roller 153 on a split ring in a recess in the part and the key which has a projection engageable with the roller can only be inserted or withdrawn when a cavity 156 in the casing 110 aligns with the roller. The key has a finger piece 24 with a hollow shaft 26 with fingers of different lengths fitted in axial peripheral grooves 25. A clamping collar, 35 screws on the finger piece and holds a shoulder on each finger against an end of the finger piece. The key has a rib 28 to enter a notch 29 in the casing and an internal rib 30 or ribs to enter a groove 31 or grooves in the body part.
Patent GB-1251094-A (GB)
IPC: E04H4/00
Filed: 1969-10-20
Abstract: 1,251,094. Swimming pools. R. F. DEVELOPMENT CO. Ltd. Oct. 20, 1969, No. 51341/69. Heading A4N. A collapsible paddling pool comprises a polygonal base 1 and an upstanding wall 2 secured about the periphery of the base and having a plurality of substantially plane wall elements 3 each connected at its opposed vertical edges to respective neighbouring wall elements, each element 3 including a substantially rigid rectangular reinforcement 11 of sheet material such as hardboard whereby each element is flexibly secured to its neighbours by a narrow web 10. The web 10 is so narrow that connected elements are only allowed relative movement about an axis lying within the web. The base is formed from a single heavy-gauge plastics sheet and the wall 2 is formed by two plastics sheets 4, 5 surrounding the sheets 11 and heatsealed at 6 and (7), (8) and (9), Figs. 2 and 3 (not shown). The seal at (7) is inboard of the side wall to facilitate scaling to the base. A drain hole 12 is closed by a captive plug 13.