baber/WOPTO huggingface dataset:
Patent NZ-200280-A (NZ)
Title: Method and apparatus for dispensing predetermined dose of sample liquid into receptor cell
Inventor: GUIGAN J
IPC: G01N21/75
Filed: 1982-04-08
Abstract: A rotor (1) for performing a chemical reaction such as biological analysis with a sample liquid comprises: a rotatable container (2) having a vertical axis of rotation; a radially inner basin having radial partitions (4) dividing the basin into a plurality of compartments (3) for receiving an approximately-determined volume of the sample liquid, the approximately-determined volume being greater than the predetermined dose; a plurality of receptor cells (5) regularly distributed around the periphery of the rotor for receiving the liquid in the predetermined doses; and radially intermediate apparatus for conveying the liquid from the compartments to corresponding receptor cells under the effect of centrifugal force when the rotor is caused to rotate. The radially intermediate apparatus includes dispensing predetermined doses, which apparatus comprises, between each compartment (3) in the basin and a corresponding receptor cell (5), a measurement chamber (7) having an inlet orifice (6) in communication with the compartment (3), and an outlet orifice (8). The inlet and outlet orifices delimit a volume corresponding to the predetermined dose. The outlet orifice (8) leads passages (9, 10) responsive to the direction of rotation of the rotor to direct liquid issuing therefrom either to an overflow chamber (11) when the rotor is rotating in a first direction (A), or else to the receptor cell (5) when the rotor is rotating in a second, opposite direction (B).
Patent NZ-206305-A (NZ)
Title: Benzazepine and benzodiazepine derivatives and pharmaceutical compositions
Inventor: REIFFEN M
IPC: C07D223/16
Filed: 1983-11-17
Abstract: Compound of general formula I   <IMAGE> (wherein R1 to R6, A, B, E and G are as defined in claim 1) and acid addition salts thereof. The new compounds have valuable pharmacological properties, in particular a heart-rate lowering effect. Processes for preparing the new compounds and pharmaceutical compositions containing them are also described.
Patent NZ-214364-A (NZ)
Title: Purine and pyrimidine derivatives of desoxyribose and pharmaceutial compositions
Inventor: GRINDEY G B
IPC: C07H19/06
Filed: 1985-11-28
Abstract: Difluoronucleosides are useful for treating neoplasms in mammals.
Patent NZ-218864-A (NZ)
Title: Preparation of 7-substituted-1-alkyl or cycloalkyl- 6,8-difluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acids
Inventor: WEMPLE J N
IPC: C07D215/56
Filed: 1987-01-08
Abstract: An improved process for the preparation of 7-substituted amino-l-alkyl- or cyclopropyl-6,8-difluoro-l,4-dihydro-4-oxo-3-quinolinecarboxylic acids is described where tetrafluorobenzoyl chloride is converted in three operations via l-alkyl or l-cycloalkyl-l,4-dihydro-6,7,8-trifluoro-4-oxo-­quinoline-3-carbonitrile which in a separate step or in situ is displaced and hydrolyzed to the desired product.
Patent NZ-230654-A (NZ)
Title: Anti-cell proliferative penta and hexa peptides
Inventor: LAERUM OLE DIDRIK
IPC: A61K38/08
Filed: 1989-09-14
Abstract: Pentapeptides and derivatives thereof, including derivatives having one or more additional amino acids inserted in the sequence and/or added at the C- and N-termini, have been found to possess good activity in the inhibition of stem cell proliferation. In addition groups of novel peptides are disclosed, having improved and/or specifically directed inhibitory actions.
Patent NZ-233273-A (NZ)
Title: Oxazole substituted normonyl compounds: pharmaceutical compositions, preparation and use thereof
Inventor: O'HANLON PETER JOHN
IPC: C07D413/14
Filed: 1990-04-10
Abstract: A compound of formula (I): <CHEM> in which Ro denotes an optionally substituted isoxazol-5-yl, fury-2-yl or fur-3-yl group, has anti-bacterial and anti-mycoplasmal activity and may be prepared by a variety of processes from suitable derivatives of monic acid A.
Patent NZ-238827-A (NZ)
Title: Angiotensin ii immunoassay and kit, the antibodies used and angiotensin-related peptides
Inventor: SIMON DOMINIQUE
IPC: G01N33/53
Filed: 1991-07-03
Abstract: A kit for the specific determination of angiotensin II, comprising:
 anti-Ang II antibody,
 a solution of labelled Ang II,
 solutions containing Ang II standards in known and increasing concentrations,
 the requisite washing solution(s),
 a solution of anti-Ang III antibody, this antibody exhibiting a cross- reaction with Ang II of less than 10%, and preferably less than 5%,
 and, where appropriate, a solution of anti-Ang I antibody and/or a solution of anti-pentapeptide antibody and/or a solution of anti- hexapeptide antibody, these antibodies exhibiting a cross-reaction with Ang II of less than 10%, and preferably less than 5%. 
<??>The peptide derivatives and the specific antibodies to these derivatives for use in the kit, and a method of determination of angiotensin II using this kit are also described.
Patent NZ-242642-A (NZ)
Title: 3'- and/or 5'-substituted 4-[2-(2-hydroxy-2-phenylamino)ethoxy]phenylacetic acid derivatives, medicaments and precursors
Inventor: HOLLOWAY BRIAN ROY
IPC: A61K31/19
Filed: 1992-05-07
Abstract: Compounds of the formula (I): <CHEM> and bioprecursors and pharmaceutically acceptable salts thereof are described as  beta 3-adrenoceptor agonists having anti-obesity, hypoglycaemic and related therapeutic utilities. Processes for their preparation are described as are compositions containing them.
Patent NZ-244457-A (NZ)
Title: Substituted taxanes and antineoplastic compositions
Inventor: HOLTON ROBERT A
IPC: C07F7/00
Filed: 1992-09-23
Abstract: A taxane derivative of the formula <CHEM>  wherein R<5> and R<7> are independently selected from the group comprising phenyl, naphthalene, C1/4 H psi CHCH-, and <CHEM>  provided, however, R<5> and R<7> are not both phenyl;     Q is CH<7>-, (CH<7>)<7>C-, CH<7>O-, Cl, Br, F, NO<6>, <CHEM>     Z is -OT<5>,     T<5> is hydrogen, hydroxyl protecting group, or -COT<6>, T<6> is H, C<5>-C1/4  alkyl, C<5>-C1/4  alkenyl, C<5>-C1/4  alkynyl or monocylic aryl,     Ac is acetyl, and E<5> and E<6> are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor agents.
Patent NZ-248315-A (NZ)
Title: Linking apparatus with auger flightings to compress sausage strand at linking points
Inventor: TOWNSEND RAY T
IPC: A22C11/10
Filed: 1993-08-03
Abstract: Three parallel auger shafts (44) having identical flighting (46) thereon disposed on axes equally spaced from each other to provide a central axis (52) equidistant from the axes of the augers. An elongated strand (54) of extruded meat product is moved through the central axis thereof so that when the flighting on the augers meet at a common point, the diameter of the strand is compressed to create a link (56) in the strand. A second embodiment of the invention places the three augers (44) in a rotatable assembly with the augers (44) rotating about their own axes as well as the central axis. A third embodiment utilizes a casing control element (78) on the inlet end of each auger (44) to cooperate with the nozzle or horn (16) through which the extruded material is being delivered whereupon the control elements (78) rotate the casing material and control the expansion of the casing material to its full diameter as the meat emulsion flows into the casing. <IMAGE>
Patent NZ-250041-A (NZ)
Title: Forming base on container; heated thermoplastics strip bonded to exposed end of container using die and punch
Inventor: LAJOVIC DUSAN SAVA
IPC: B29C65/20
Filed: 1993-10-22
Abstract: An apparatus (1) for forming a base (2) on a tubular container (3). The apparatus comprises a die (5), and a punch plate (7) having an aperture (8) defining an open end of the die (5). A punch (10) is co-operable with the punch plate (7) and the die (5). Transport means are provided to feed a strip (22) of hot thermoplastic material between the punch (10) and the punch plate (7). Locating means (12) locate the container (3) such that one end extends marginally into the die (5). The punch (10) is selectively operable in a single stroke to shear off a slug of the material by forcing the strip (22) against the plate (7) and to punch (10) the slug through the aperture (8) into forming engagement with the die (5). A peripheral edge of the slug is thereby thermoplastically bonded to the exposed end of the container (3) within the die (5) to form the base (2). <IMAGE>
Patent NZ-269633-A (NZ)
Title: In-situ cleaning of contaminated heterogeneous soil, using electrolysis
Inventor: BRODSKY PHILIP HYMAN
IPC: A62D3/00
Filed: 1994-06-16
Abstract: A process for the in-situ remediation of a contaminated heterogeneous soil region comprising: (a) introducing material for treating contaminants in a contaminated heterogeneous soil region into at least one liquid permeable region within the contaminated heterogeneous soil region to form at least one treating zone within the contaminated heterogeneous soil region, (b) transmitting direct electric current through at least one low permeability soil region within the contaminated heterogeneous soil region between a first electrode and a second electrode having opposite charge, wherein (i) the first electrode is located at a first end of the contaminated heterogeneous soil region and the second electrode is located at the opposite end of the contaminated heterogeneous soil region or (ii) the first electrode is located at a first end of each of the low permeability soil regions and the second electrode is located at the opposite end of each of the low permeability soil regions, (1) to cause an electroosmotic flow from the second electrode to the first electrode, (2) to cause an electromigratory movement of ionic contaminants in a direction toward the electrode of opposite charge, or (3) to cause an electroosmotic flow from the second electrode to the first electrode and an electromigratory movement of ionic contaminants in a direction toward the electrode of opposite charge, and (c) applying a hydraulic gradient across the contaminated heterogeneous soil region to cause a hydraulic flow from the high pressure end of the contaminated heterogeneous soil region to the low pressure end of the contaminated heterogeneous soil region.
Patent NZ-277144-A (NZ)
Title: Shaft for sheet winder; expandable shaft for winding nonwoven material has openings or grooves which house blades radially movable along the shaft so as to vary its diameter
Inventor: ANDERSSON ANDERS
IPC: B65H75/24
Filed: 1994-11-23
Abstract: PCT No. PCT/SE94/01114 Sec. 371 Date Aug. 1, 1996 Sec. 102(e) Date Aug. 1, 1996 PCT Filed Nov. 23, 1994 PCT Pub. No. WO95/14630 PCT Pub. Date Jun. 1, 1995Expandable shaft for winding elongated material, especially soft paper and other nonwoven material. The shaft (10) has a number of radial openings (13) or grooves (22, 24) which house longitudinal blades (23), bars (11) or the like in such a way that these are movable by means of activating means (14, 15, 25) in a radial direction between a retracted and a projected position, whereby a variable effective diameter of the shaft is created. The radial openings (13) or grooves (22, 24) are arranged with a spiral formed inclination in the longitudinal direction of the shaft (10) and the retractable and projectable blades (23) or the bars (11) housed therein are arranged with a corresponding spiral form along the shaft.
Patent NZ-313816-A (NZ)
Title: Use of 19-nor-vitamin D compounds for the prevention of hyperphosphatemia
Inventor: DELUCA HECTOR F
IPC: A61K31/593
Filed: 1996-07-09
Abstract: A calcitriol analog of 19-nor-vitamin D shown as Formula (I), particularly 19-nor-1,25-(OH)2D2 possess low calcemic and phosphatemic activity while also having the ability to suppress parathyroid hormone (PTH) production. The suppressive effect on PTH secretion of these 19-nor analogs without significant changes in serum calcium or serum phosphorus is useful for the treatment of secondary hyperparathyroidism in patients having kidney disorders. Wherein; X1 and X2 each represent, independently, hydrogen or a hydroxy-protecting group; R is represented by Formula (II), wherein the stereochemical center may have the R or S configuration, and where Z is selected from Y, -OY, -CH2OY, -C=CY and -CH=CHY, where the double bond may have the cis or trans geometry, and where Y is selected from hydrogen, methyl, -CR5O and a radical of the structure represented by Formula (III); wherein m and n represent 0 to 5, R1 is selected from hydrogen, hydroxy, protected hydroxy, fluoro, trifluoromethyl, and C1-5alkyl, which may be straight chain or branched and, optionally, bear a hydroxy or protected-hydroxy substituent; and where each of R2, R3, and R4, independently, is selected from hydrogen, fluoro, trifluoromethyl and C1-5alkyl, which may be straight-chain or branched, and optionally, bear a hydroxy or protected-hydroxy substituent; and where R1 and R2, taken together represent an oxo group, or an alkylidene group, =CR2R3, or the group -(CH2)p-, where p is an integer from 2 to 5; and where R3 and R4, taken together, represents an oxo group, or a group -(CH2)q-, where q is an integer from 2 to 5; and where R5 represents hydrogen, hydroxy, protected hydroxy, or C1-5alkyl.
Patent NZ-331381-A (NZ)
Title: Substituted 4-hydroxy-phenylalcanoic acid derivatives
Inventor: WILLSON TIMOTHY MARK
IPC: C07D213/70
Filed: 1997-02-26
Abstract: The compound has the formula I wherein: A is optionally substituted phenyl, 5 or 6 membered heterocyclic group containing at least one heteroatom selected from O, N or S or a fused bicyclic ring containing a heterocyclic ring as defined above wherein the bicyclic ring is attached to group B via a ring atom of heterocyclic ring; B is alkylene, M-alkylene, alkylene-M, 5 or 6 membered heterocyclic group containing at least one N heteroatom and optionally at least one heteroatom selected from O, N or S or Het-alkylene; M is O, S or NR2; R2 is H or alkyl; Het is 5 or 6 membered heterocyclic group containing at least one N heteroatom and optionally at least one heteroatom selected from O, N or S; Alk is alkylene; R1 is H or alkyl; Z is (alkylene)-optionally substituted phenyl or NR3R4; R3 is H or alkyl; R4 is -Y-CO-T-R5 or -Y(CH(OH))-T-R5 and Y, T and R5 are as defined in the specification. A pharmaceutical composition thereof is useful in the treatment of a PPAR-gamma mediated disease.
Patent NZ-332713-A (NZ)
Title: Substituted 1,3-benzodioxoles and use as antidiabetic, antihyperglycemic, and antiobesity agents
Inventor: GILBERT ADAM MATTHEW
IPC: A61P3/00
Filed: 1997-05-09
Abstract: These compounds, which have anti-diabetic and/or antihyperglycemia and/or anti-obesity activity, have the formula (II), where: R1 and R6 are independently hydrogen, alkyl, trifluoromethyl, cyano, alkoxy, or halogen; R2 is hydrogen or trialkylsilyl; R3 is hydrogen or alkoxycarbonyl; or R2 and R3 are joined to form a ring (a): where R' is hydrogen, alkyl or aryl; R4 and R5 are independently hydrogen or alkyl; R7 and R8 are independently OR9 or NR10R11; R9 is hydrogen, alkyl, cycloalkyl, silylalkyl, aryl, arylakyl, alkoxyalkyl, heteroaryl, -CHR12COOR13, -CHR12C(O)R13, -CHR12CONR10R11, -CHR12OCOOR13, or -CHR12OC(O)R13, with the provision that R9 is not hydrogen in both R7 and R8; R10 and R11 are independently hydrogen, alkyl, aralkyl, aryl, furanylalkyl, or alkoxycarbonylalkyl; R12 and R13 are independently hydrogen, alkyl, aryl, or aralkyl; and their pharmaceutically acceptable salts thereof, the enantiomers thereof, the racemic mixtures thereof, and the diastereomeric mixtures thereof.
Patent NZ-333142-A (NZ)
Title: Method of procuring commodities comprising a quotation request step from identified suppliers
Inventor: RUFFE LEONARD JAMES
IPC: G06F19/00
Filed: 1998-12-01
Abstract: A computer system is utilized to produce an optimal commodity procurement cost.  The specifications and amount of the commodities to be procured in a particular time period are determined, the cost of the commodities to be procured is tracked, and an executive commodity report is developed.  From a potential commodity supplier list and a set of sourcing parameters for selecting suppliers from potential suppliers, a request for quotations for each commodity to be procured is developed and communicated to the respective suppliers who return quotations for the supply of the commodity.  The quotations received are analyzed with respect to the set of sourcing parameters, and for each commodity, on the basis of the analysis, the commodity is ordered from the optimal cost supplier.
Patent NZ-337888-A (NZ)
Title: Use of eprosartan to treat isolated systolic hypertension
Inventor: BROOKS DAVID P
IPC: A61K31/4178
Filed: 1998-05-27
Abstract: Disclosed is the use of eprosartan, (E)-á-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene-2-thiophenepropionic acid monomethanesulfonate, for the treatment of isolated systolic hypertension.
Patent NZ-501674-A (NZ)
Title: Data processing system for integrated tracking and managing commerce related activities on a public access network
Inventor: MESSER STEPHEN DALE
IPC: G06Q20/00
Filed: 1998-04-14
Abstract: A data processing system for establishing, managing and tracking commercial transactions undertaken on a wide access network, comprises: a Content Provider site interconnected to the network and programmed to display to a USER visiting the Content Provider through a site content viewing program, information about one or more products or services available for commercial transactions, at a site separate from the Content Provider, wherein the display includes associated with the information, linking instructions for directing the USER's viewing program to a site separate from the Content Provider site, and the linking instructions further comprise code for associating with the visiting USER, a unique USER identification code inserted onto the USER http command line and/or passed along in the USER URL; a Clearinghouse site interconnected to the network and programmed to receive information regarding display of or selection of the display information on the Content Provider site, and the ability to read the USER unique identification code, and store the code in memory, and further, to provide connection of the USER to an identified Target Merchant Site, wherein the Target Merchant Site is associated to the display information and a Target Merchant site interconnected to the network and programmed to provide the ability to transact the product and/or services; wherein the Target Merchant site is further programmed to record information about a purchase made by the USER and to communicate the purchase information back to the Clearinghouse site, wherein the purchase information is used by the Clearinghouse server to allocate credit to the Content Provider.
Patent NZ-506021-A (NZ)
Title: Process for making floating objects in synthetic resins reinforced with continuous fibres utilising two winding mandrels
Inventor: HAMLYN ALEXANDRE
IPC: B29C70/54
Filed: 1999-02-04
Abstract: A technique for manufacturing floating bodies, such as a boat's hull or part of such a hull, made of synthetic resins reinforced by continuous fbres, said technique including at least one filament winding step.
Patent NZ-506715-A (NZ)
Title: Packaging machine with rollers through which complementary closure strips are fed transverse to the film
Inventor: PULLEN CRAIG
IPC: B65B41/16
Filed: 2000-09-04
Abstract: A form, film and seal machine having a characteristic reclose tape (300) feeding apparatus (200).  Roller drive means comprising an upper roller (406) and a lower roller (408) frictionally engage the webs (310, 320) incorporating the reclose elements (312, 314).  The rollers (406, 408) are disposed at an entry end of the guides (170, 180) that are disposed transversely of the film (F).  The rotation of rollers (406, 408) is controlled to intermittently draw in a required length of reclose tape (300) and slide it along the guides (170, 180).  Following severing and sealing of the reclose tape (300) to the film (F) the operation is repeated at bag forming intervals.  The feeder apparatus (200) is in the nature of a carriage positioned over the film (F) path.  The carriage incorporates adjustment means (420, 414) to set the position of the reclose tape (300) relative to the film (F).
Patent NZ-507713-A (NZ)
Title: Crystalline efavirenz
Inventor: RADESCA LILIAN A
IPC: C07D265/18
Filed: 1999-06-10
Abstract: A process of producing a crystalline form of Efavirenz; wherein a saturated alkane solution of Efavirenz is rapidly crystallised. The crystalline form is characterised by an x-ray powder diffraction pattern comprising five or more 2è values selected from: 6.8±0.2, 9.2±0.2, 12.3±0.2, 16.2±0.2, 21.4±0.2, 22.7±0.2, 24.1±0.2, and 28.0±0.2.
Patent NZ-507751-A (NZ)
Title: An actuator, typically for back wash valve, with sleeve shuttle moved between two positions, to allow inlet and exhaust flow, to and from housing ports and inner conduit
Inventor: TIMNEY BRYSON RICHARD
IPC: F16K31/06
Filed: 2000-10-25
Abstract: The actuator has a body member 1 defining a cylindrical bore and extending from the cylindrical bore there is an inlet conduit 3 and an exhaust conduit 4, and an operating conduit 5. A sleeve shuttle 2 is located in the bore and can travel between two conditions within the bore n an axial direction. The sleeve shuttle 2 in the first condition provides a fluid connection between the inlet conduit 3 and the operating conduit 5. The exhaust conduit 4 is sealed from the other of the conduits 3,5. In the second condition the sleeve shuttle2 provides a fluid connection between the operating conduit 5 and the exhaust conduit 4 wherein the inlet conduit 3 is sealed. An actuation means 11 selectively displaces the shuttle 2 to the first condition, and a means is provided to move the sleeve shuttle to the second condition.
Patent NZ-507912-A (NZ)
Title: Nonapeptide antiangiogenic drugs
Inventor: HENKIN JACK
IPC: A61P31/04
Filed: 1999-05-21
Abstract: Peptides having the formula: A0-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10 wherein A0 is hydrogen or an acyl group; A10 is a hydroxyl group or an amino acid amide; and A1, A2, A3, A4, A5, A6, A7, A8 and A9 are amino acyl residues as defined in the specification.  The peptides are useful in the treatment of angiogenesis related conditions such as cancer, arthritis, psoriasis, angiogenesis of the eye associated with infection or surgery, macular degeneration and diabetic retinopathy.  A method for isolating a receptor from an endothelial cell using the peptides is also described.
Patent NZ-508983-A (NZ)
Title: High frequency crystal oscillator in a closed circuit configuration with logic gate feedback elements
IPC: H03B5/36
Filed: 2000-12-19
Abstract: The natural frequency of a crystal oscillator has been found to be linked to its thickness. That is, a change in the mass of the crystal can lead to a change in its natural frequency. To avoid this, it is desirable to use an oscillator having a high natural frequency. But the down side to this is that the crystal oscillator will have to be thin and hence fragile. To overcome this, the circuit disclosed uses the crystal oscillator (X3) in a closed circuit with a serially connected capacitor (C3) to create a high frequency oscillation. The circuit also employs a resistor in parallel with this arrangement (R1/R2). The closed circuit starts at the output of a logic element (IC2) and ends at a logic element (IC1). This arrangement can allow for the natural frequency to be in the preferable range of 30 - 1800 MHz. The application of this stable high frequency oscillator includes super-high sensitive measuring devices, since the circuit is able to discriminate delicate changes in the natural frequency of the oscillator.