baber/WOPTO huggingface dataset:
Patent EP-1517992-A2 (EP)
Inventor: ROZWADOWSKI KEVIN L
IPC: C12N5/06
Filed: 2003-06-05
Abstract: L'invention concerne des procédés et des acides nucléiques recombinés utilisés pour modifier un acide nucléique recherché dans un locus cible du génome d'un organisme hôte. Dans certains aspects, l'invention concerne la production in vivo d'un substrat de ciblage de gène (GTS), qui peut contenir à la fois des composants ADN et ARN. Le substrat de ciblage de gène peut contenir une séquence de ciblage de gène (GTNS), laquelle est homologue au locus cible tout en présentant toutefois une modification de séquence par rapport au locus cible. Le substrat de ciblage de gène peut être obtenu par transcription inverse d'un ARN messager de ciblage (ARNgtm). L'ARN messager de ciblage de gène peut être enroulé en vue de l'auto-amorçage de la transcription inverse par une transcriptase inverse. L'ARN messager de ciblage de gène peut être en outre le produit de transcription d'un produit recombiné de ciblage de gène (GTC) qui code l'ARN messager de ciblage de gène. Le produit recombiné de ciblage de gène peut être, par exemple, une séquence d'ADN intégrée dans le génome d'un organisme hôte ou dans un élément extrachromosomique. Après l'expression des systèmes de ciblage de gène, des organismes hôtes présentant des modifications génomiques sur le locus cible qui correspondent à la modification de séquence présente dans la séquence nucléotidique de ciblage de gène, peuvent être sélectionnés, par exemple. Dans certains modes de réalisation, la structure de retrons peut être adaptée en vue de son utilisation dans les systèmes de ciblage de gène de l'invention.
Patent EP-1534963-A2 (EP)
Inventor: MCCONKEY JAMES
IPC: F16B39/28
Filed: 2003-06-03
Abstract: The present invention relates to safety nut and bolt and more specifically to a safety nut and bolt which can be easily joined together but cannot then be unscrewed in a typical fashion. The invention tilises a clutch brake mechanism to prevent normal unscrewing of the elements.
Patent EP-1513571-A2 (EP)
Inventor: RUBIN KEITH H
IPC: A61M5/32
Filed: 2003-05-09
Abstract: An auto-injector comprising: a housing having a forward end; a container in the housing containing an injectable medication; an injection needle having a sharp forward end, the needle being connectible with the interior of the container to enable medication to flow to and through the needle, the needle being movably mounted with respect to the housing between a retracted position and an injection position forward of the retracted position; a needle shield movably mounted to the housing and having a needle-receptive passageway formed therethrough, the needle shield being movable between a retracted position in which it covers the sharp forward end of the needle when the needle is in its retracted position, a triggering position located rearwardly of the retracted position and an extended position disposed forwardly of the retracted position in which the needle shield covers the sharp forward end of the needle in its injection position; means responsive to movement of the needle shield from its retracted position to its triggering position for moving the needle from its retracted position to an injection position; and means responsive to movement of the injection needle to its injection position for causing medication to flow to and through the needle.
Patent EP-1539744-A2 (EP)
Inventor: RAJU BORE G
IPC: C07D205/04
Filed: 2003-07-11
Abstract: La présente invention concerne de nouveaux dérivés de N-hydroxyamide. Ces dérivés de N-hydroxyamide inhibent la UPD-3O-(R-3-hydroxymyristoyle)-N-acétylglucosamine désacétylase, une enzyme présente dans les  bactéries Gram négatif, et sont ainsi utiles comme agents anti-microbiens ou antibiotiques. L'invention a également pour objet des procédés de synthèse et d'utilisation de ces composés.
Patent EP-1538903-A2 (EP)
Inventor: DUFFY JOSEPH
IPC: A61K31/381
Filed: 2003-09-08
Abstract: L'invention concerne l'utilisation de dérivés de thiophène substitués, ainsi que des compositions contenant ces composés qui permettent de traiter le diabète de type 2. Les composés de l'invention sont des antagonistes du glucagon. Lesdits composés bloquent l'action du glucagon au niveau de son récepteur et font ainsi baisser les niveaux de glycémie veineuse, ce qui constitue un traitement contre le diabète.
Patent EP-1507626-A2 (EP)
Inventor: LEFEBVRE PHILIPPE
IPC: B23K26/14
Filed: 2003-04-11
Abstract: Procédé de soudage hybride arc-laser de plusieurs pièces (1 à 4) métalliques à souder mettant en œuvre au moins un faisceau laser et au moins un arc électrique caractérisé en ce que lesdites pièces métalliques (1 à 4) sont superposées en une configuration multi-épaisseurs et en ce que ledit faisceau laser et ledit arc électrique viennent souder sur chants (1a à 4a) ladite configuration multi-épaisseurs (1a, 2a, 3a, 4a).
Patent EP-1525324-A2 (EP)
Inventor: PREAUDAT MARC
IPC: C12Q1/34
Filed: 2003-07-31
Abstract: The invention relates to a method for determining endoglycosidase enzyme activity, and in particular of the heparanase type, in a sample, and also to a method for detecting a compound capable of modulating the activity of an endoglycosidase, and in particular of an endoglycosidase having activity of the heparanase type, by measuring a signal resulting from a close proximity transfer between two compounds attached to a substrate for the enzyme.
Patent EP-1543278-A2 (EP)
Title: Systeme automatique maintenant des echantillons a une temperature regulee
Inventor: ANGELANTONI GIANLUIGI
IPC: F25D25/00
Filed: 2003-09-25
Abstract: L'invention porte sur un système automatique (100) de maintien d'échantillons à une température régulée comportant: (i) au moins une chambre de conservation (1) isolée thermiquement, à température régulée par un dispositif (3) ad hoc, et contenant un ensemble de disques (9) de stockage des échantillons (19), (ii) et un robot (4) cartésien, muni d'un préhenseur (18) placé dans une chambre supérieure (2) séparée de la chambre (1) par une plaque isolante (6), et qui déplace les échantillons (19), en passant par un portillon (7) à accès contrôlé, entre un tiroir d'E/S (20) et le susdit ensemble de disques (9). Les mouvements combinés et synchronisés du robot (4) et de chacun des disques de l'ensemble permettent d'accéder à tous les emplacements de stockage. La gestion des dispositifs du système automatique (100) est assurée par un système à CN piloté par un SW de gestion.
Patent EP-1546860-A2 (EP)
Title: Systeme et procede de traitement de codes d'identification
Inventor: KIRKPATRICK FICUS
IPC: H04L29/08
Filed: 2003-09-29
Abstract: L'invention concerne un procédé consistant à associer plusieurs types d'objets de données à plusieurs codes d'identification (ID) d'objets de données dans une première base de données sur un service de données et dans une seconde base de données sur un dispositif hertzien, à réaliser une requête sur la seconde base de données, sur le dispositif hertzien, afin de déterminer si un code ID d'objet associé existe concernant un premier type d'objet de données, à émettre le code ID d'objet à partir du dispositif hertzien en direction du service si le code ID d'objet associé existe, sensible au premier type d'objet de données utilisé par une application sur le dispositif, et à émettre une chaîne représentant le premier type d'objet de données à partir du dispositif hertzien si aucun code IF d'objet associé n'existe concernant le premier type d'objet de données.
Patent EP-1513501-A2 (EP)
Title: Emulsions simples et multiples destinees a la detoxication de l'organisme ou de surfaces
Inventor: DOBIN-ASSOULY ELISE MONA-LYDIA
IPC: A61P43/00
Filed: 2003-06-04
Abstract: La présente invention concerne l'utilisation d'émulsions simples ou multiples comprenant dans leur phase organique un ou plusieurs composés extractants capables, lorsque lesdites émulsions sont mises en contact avec un milieu externe, soit biologique tel que le liquide gastrique, la peau ou le sang, soit artificiel tel que des surfaces métalliques ou plastiques, d'extraire dudit milieu externe des molécules toxiques déterminées susceptibles de se lier audit ou auxdits extractants, pour la détoxication soit par voie orale, topique ou parentérale, soit par simple application sur la surface susmentionnée.
Patent EP-1513424-A2 (EP)
Title: Helmet
Inventor: KNAUER HANS-GEORG
IPC: A42B3/04
Filed: 2003-06-11
Abstract: The invention relates to a helmet (12), particularly a bicycle helmet, comprising an adjusting device (30, 40) in order to adapt the size of the helmet (12) to the size of the head of an individual wearing the helmet (12). A rear light (60) is provided on the adjusting device (30, 40).
Patent EP-1551941-A2 (EP)
Title: Fabrication d'huiles de base de graissage
Inventor: MURPHY WILLIAM J
IPC: C10G45/58
Filed: 2003-10-07
Abstract: Procédé de fabrication d'huile de graissages de haute qualité consistant à traiter par l'hydrogène une charge paraffinique pour produire une charge traitée par hydrogène, puis à hydrodéparaffiner la charge paraffinique et la soumettre à un hydrofinissage.
Patent EP-1570179-A2 (EP)
Inventor: OTTO DIETER
IPC: F04C2/10
Filed: 2003-11-12
Abstract: Innenzahnradpumpe, insbesondere Kraftstoffförderpumpe, wobei ein Ritzel der Innenzahnradpumpe durch einen Exzenterantrieb angetrieben wird.
Patent EP-1566068-A2 (EP)
Inventor: CRICCO REMY
IPC: H04W8/24
Filed: 2003-11-13
Abstract: The application loading method has a server loader (1) for an application including a first application part to a terminal (2). The data is provided for charging forming a second application part in the server. The server constructs an application message containing the first part of the application, and transmits the message from the server. The first application part is installed in the terminal. The second application part is then loaded, extracting the application message.
Patent EP-1586054-A2 (EP)
Title: Procede, systeme, et programme d'ordinateur de securisation au sein d'un reseau informatique global
Inventor: ALAGNA MICHAEL ANTHONY
IPC: G06F21/00
Filed: 2003-12-11
Abstract: Dans un premier aspect, un système de traitement de données détermine si une ressource risque d'être mal représentée comme une ressource de confiance au sein de l'ensemble du réseau informatique. Dans un deuxième aspect, le système de traitement de données émet en sortie une indication si une ressource au sein de l'ensemble d'un réseau informatique est reconnue comme une ressource de confiance.
Patent EP-1583472-A2 (EP)
Inventor: RULE PETER
IPC: A61B5/15
Filed: 2003-12-30
Abstract: An analyte detection system (1709) for analysis of a body fluid is provided, comprising an analysis portion and a sample collection portion which is configured to be removably coupled to the analysis portion. The analysis portion comprises a detector (250) configured to detect electromagnetic radiation and a source of electromagnetic radiation (220). The source is positioned with respect to the detector such that electromagnetic radiation emitted by the source is received by the detector. The sample collection portion comprises a housing, a lance (1704) and a sample chamber (1734). The lance is mounted within and moveable with respect to the housing. The sample chamber is configured to be positionable, upon coupling of the sample collection portion to the analysis portion, with respect to the source and detector such that at least a portion of any electromagnetic radiation emitted by the source passes through the sample chamber prior to being received by the detector.
Patent EP-1438992-A2 (EP)
Inventor: YOSHIHIKO SHIODA
IPC: A63B69/36
Filed: 2004-01-15
Abstract: A golf practice and exercise mat having two striking contours (20,30) with different
heights and contours of artificial grass which gives golfers practice and exercise by
swinging a golf club through the contoured pile that applies resistance to the golf club as
the club head travels though the pile, thus enhancing strength and improving muscle
memory. One contour, for irons (20), has the grass pile of the carpet increasing in height at a
moderate, curved upward slope to an apex and then decreasing in height at a gradual,
linear downward slope. The second contour, for woods (30), has the grass pile increasing in
height at a gradual approximately linear slope until a transition point is reached at which
the grass strand height increases in a single step change to a height at least two times
greater than the height of the previous pile, and then decreasing in height in a linear
downward slope.
Patent EP-1462354-A2 (EP)
Inventor: MATSUMOTO SHINYA
IPC: B62M11/06
Filed: 2004-03-16
Abstract: A transmission apparatus (T) is capable of retaining an endless transmission
chain (48) on a rotatable member (30, 40), even where a small inter-axis
distance remains between two rotatable shafts (11, 24) to which each of two
rotatable members (30, 40) is drivingly connected. The transmission (T)
includes a drive sprocket member (30) for connecting to a main drive shaft (11).
The transmission (T) also includes a driven sprocket member (40), connected
to the output shaft (24) in parallel with the main drive shaft (11) and including a
plurality of transmission sprockets (41-47). The transmission (T) further
includes a chain (48) interconnecting both sprocket members (30, 40), and a
transmission shift mechanism (M2) for positioning the chain (48) among the
transmission sprockets (31, 41-47). The drive sprocket member (30) is
supported at the main drive shaft (11) in the rotary center line direction, in such
a way that the chain (48) is applied to both sprocket members (30, 40) in
parallel with a plane crossing at a right angle with the rotary center line of the
main drive shaft (11).
Patent EP-1481834-A2 (EP)
Inventor: ISHIGAMI AKIHIRO
IPC: F02M35/12
Filed: 2004-05-27
Abstract: In an air intake system, a rear tower (41) having a space
(41b) interiorly is provided on the top surface of a body
frame, a rear pillar (29) having a passageway (29a)
interiorly is mounted on the rear tower, an air intake
port (29b) communicating with the passageway is provided
in the rear pillar, the passageway and the space within
the rear tower are connected together, an expansion
silencer (42) is connected to the space of the rear tower,
and an air cleaner (43) is connected to the expansion
silencer. The top surface (45a) of a working oil tank
(45) is rendered lower than the upper end (46a) of a side
plate (46) to form a space above the top surface, where
the expansion silencer is provided. Abase bracket (50a)
is mounted to the air cleaner, a support bracket (50b)
is mounted on the side plate, and the base bracket is
mounted on the support bracket to support the air cleaner
above the expansion silencer.
Patent EP-1491413-A2 (EP)
Inventor: FISCHER JOACHIM
IPC: B60R21/26
Filed: 2004-06-02
Abstract: The gas generator (10) has an outer casing with holes to allow the escape of gas to inflate the airbag. A pressure container (12) is closed by a bursting disk (16). When the disk bursts the gas presses against the closed end (28) of a cylindrical valve element (24). The valve element fits inside an outlet chamber (14) and the closed end is pushed in by the gas pressure so that it progressively uncovers ports in the thick sidewalls (18) of the outlet chamber.
Patent EP-1492200-A2 (EP)
Inventor: MASUDA TAKATO
IPC: H01F6/06
Filed: 2004-06-08
Abstract: A phase split structure of a superconducting cable includes three cable cores (102) each having a shield layer (203) provided around a superconductor, a splitter box (1) housing the three cable cores (102) extending from an assembly portion where the three cable cores (102) are assembled into the cable, in a state in which the cable cores (102) are spaced apart from each other, and a shield connecting portion (2) connecting respective shield layers of the cable cores (102) to each other within the splitter box (1). The shield connecting portion allows the cable cores to have their respective shield layers connected together with low resistance and each shield layer can pass a current substantially equal in magnitude to that which each superconductor passes. Thus in each shield layer a magnetic field can be formed having a level that can cancel a magnetic field generated from each superconductor. The structure can thus effectively prevent a large magnetic field external to the cable core.
Patent EP-1491563-A2 (EP)
Inventor: MUENZMAY THOMAS DR
IPC: C08G18/28
Filed: 2004-06-14
Abstract: An aqueous preparation of polyurethanes comprises 2-20 wt.% in relation to solids of lateral or terminal groups containing alkyl or cycloalkyl. The aqueous preparation of polyurethanes comprises 2-20 wt.% in relation to solids of lateral or terminal groups of formula -N(H)-C(=O)-O-B-C(=O)-O-R. B : benzene;and R : alkyl or cycloalkyl. Independent claims are also included for: (1) a process for production of the inventive preparations comprising reacting in a first stage, the synthesis components i) organic compounds comprising >=2 free hydroxyl groups, capable of reacting with isocyanate groups, ii) diols and polyols having molecular weight of 62-299, iii) synthesis components for the incorporation of terminal and/or lateral ethylene oxide units of formula H-Y'-X-Y-R, iv) organic compounds having >=2 free isocyanate groups per molecule, and optionally v) synthesis components that are monofunctional according to the isocyanate polyaddition reaction and additionally contain anionic or potentially anionic group consisting of vA) mono and dihydroxy-carboxylic acids or their salts and vC) sulfonate group-containing aliphatic diols, and vii) p-hydroxybenzoic acid esters of formula H-O-B-C=(O)-O-R to form a prepolymer, the required quantities of the individual synthesis components being measured in such as way as to result in an isocyanate index of 1.05 to 4.5, then in a second stage, dissolving the prepolymer in an organic solvent and optionally in a third stage reacting the isocyanate-containing prepolymer solution with vB) mono- and/or diamino carboxylic acids or their salts and/or mono- and/or diamino sulfonic acids or their salts, and/or vi) aliphatic and/or alicyclic primary and/or secondary polyamines optionally neutralizing potentially anionic components before or after the third stage and either the components vA) or vC) being used in the first stage and/or component vB) being used in the third stage, precipitating the dispersion in a fourth stage by the addition of water and removing the organic solvent in a final stage; (2) a method of coating or producing substrates comprising applying the inventive preparations to surface of substrates; and (3) polymers coated with the inventive preparations. R : 1-12C monovalent hydrocarbon; X : polyalkylene oxide chain with 5-90 ethylene oxide units and optionally propylene oxide, butylene oxide, or styrene oxide units; Y, Y' : O or -NR'-;and R' : H or 1-18C alkyl or cylcoalkyl.
Patent EP-1493750-A2 (EP)
Inventor: BERNDT PETER
IPC: C12Q1/02
Filed: 2004-06-28
Abstract: The present invention relates to novel host cell targets for antiviral, preferably anti-hepatitis
C virus (HCV), compounds identified by analysis of HCV replicon-regulated
polypeptide expression, to prognostic markers for the prediction of the outcome of a
viral infection, to in vitro methods for the prediction of the outcome of a HCV infection
in a subject, to screening methods for identifying compounds which interact with and/or
modulate the activity of the novel host cell targets or which modulate the expression of
said novel host cell targets.
Patent EP-1493969-A2 (EP)
Inventor: PFISTER WOLFGANG
IPC: F23N5/20
Filed: 2004-06-30
Abstract: The method for the operating of an incandescent igniter element of a vehicle's heater in the starting phase entails the recording a value in dependence upon a heating capacity of the igniter element (12), comparing this value with a reference, and if the value is less than the reference increasing the heating capacity of the incandescent igniter element. In the first stage the value which is in dependence upon the heating capacity is based on a voltage applied to the igniter element and current flowing through it.
Patent EP-1495901-A2 (EP)
Inventor: WAKAO HISAAKI
IPC: B60K17/35
Filed: 2004-07-08
Abstract: A drive power transmission control device in a first embodiment is provided with
an electromagnetic type drive power transmission device and an electronic control
device (ECU) for controlling the application of electric current to an electromagnetic coil
of the electromagnetic type drive power transmission device. The ECU is bodily
provided on a casing of the electromagnetic type drive power transmission device
through at least one support member 50. Thus, nonuniformity or deflection in
mechanical quality of the electromagnetic type drive power transmission device and
nonuniformity or deflection in electrical quality of the electronic control device can be
adjusted as a whole, and the drive power transmission control device is lightened in
weight. A drive power transmission control device in a second embodiment is provided
with an electronic control device for controlling drive power transmitted by a drive
power transmission device from a drive power source to plural wheel. The electronic
control device includes a housing made of a resin and provided independently of the
drive power transmission device, a temperature sensor provided inside the housing for
detecting the temperature of the drive power transmission device, a bracket made of a
resin and formed bodily with the housing for fixing the housing on the drive power
transmission device, and a heat conduction portion provided in the bracket for
conducting the heat generated in the drive power transmission device to the
temperature sensor. Thus, the drive power transmission control device makes it
possible to reduce a work load in attaching the temperature sensor and also makes it
possible to precisely detect the temperature of lubricant oil filled in the drive power
transmission device.
Patent EP-1569286-A2 (EP)
Inventor: ZHOU ZHANG-LIN
IPC: G02F1/15
Filed: 2004-08-16
Abstract: A bistable molecular switch can have a highly conjugated first state and a less conjugated second state. The bistable molecular switch can be configured such that application of an electric field reversibly switches the molecular switch from the first state to the second state. Additionally, the bistable molecular switch can include a hydrophobic moiety and a hydrophilic moiety. Such molecular switches can be incorporated into a thin film as part of a molecular switch system which can include a layer of molecular switches between a first electrode layer and a second electrode layer. The layer of molecular switches can have substantially all of the molecular switches having their hydrophilic moiety oriented in the same direction. An electric potential can then be induced between the first and second electrode layers sufficient to switch the molecular switches from the first or second state to the second or first state, respectively. The first and second states have differences in resistivity which are suitable for use in electronic applications. Thin films containing these oriented molecular switches can be used to produce a wide variety of electronic components such as ROM memory and the like.
Patent EP-1580002-A2 (EP)
Inventor: STUDER ANTHONY D
IPC: B41J2/175
Filed: 2004-08-20
Abstract: A fluid supply (100, 800), including a body (120, 720) and a reversibly fluid absorbing material (130, 230, 330, 330', 330", 430, 730) having a first surface energy and disposed in the body. In addition, the fluid supply has at least one fiber (240, 240', 340, 340', 342, 444) having a fiber surface energy where the fiber is disposed within the fluid absorbing material, and the fiber surface energy is less than the first surface energy of the fluid absorbing material.