baber/WOPTO huggingface dataset:
Patent DE-08768112-T1 (DE)
Title: Verfahren und system zur überwachung von marktdaten zur identifizierung benutzerdefinierter marktbedingungen
Inventor: KITTELSEN DOUGLAS G
IPC: G06Q40/00
Filed: 2008-06-02
Abstract: Verfahren zum Überwachen von Marktdaten, umfassend:  Sammeln von Echtzeitdaten, welche Zustände eines Handelsmarktes betreffen, an einem Edge-Server, welcher einem Liquiditätsziel beim Handeln von mindestens einem Finanzhandelsprodukt zugeordnet ist;  Normieren der Echtzeitdaten, welche gesammelt wurden, auf eine Standardform in dem Edge-Server;  Speichern der Echtzeitdaten, welche normiert wurden, in dem Edge-Server;  Empfangen von benutzerdefinierten Kriterien, welche einen bestimmten Vorgang bei den Zuständen definieren, von einem zentralisierten Netzknoten an dem Edge-Server;  Bestimmen, ob ein Zustand in dem Handelsmarkt zu dem Vorgang passt;  Erzeugen einer Antwort, welche eine Meldung des Auftretens des Vorgangs bereitstellt; und  Senden der Antwort zu dem zentralisierten Netzknoten für eine Verteilung zu einem Benutzer, welcher den benutzerdefinierten Kriterien zugeordnet ist.
Patent CY-1108075-T1 (CY)
Inventor: ABEDI VAHAK
IPC: C07D317/72
Filed: 2007-09-19
Abstract: The present invention provides a process for the preparation of a compound of formula (I): wherein R<SUP>1 </SUP>is C<SUB>1-6 </SUB>alkyl; R<SUP>2 </SUP>and R<SUP>3 </SUP>are, independently, C<SUB>1-6 </SUB>alkyl; and R<SUP>4 </SUP>is C<SUB>1-6 </SUB>alkyl or benzyl (wherein the phenyl ring of benzyl is optionally substituted by nitro, S(O)<SUB>2</SUB>(C<SUB>1-4 </SUB>alkyl), cyano, C<SUB>1-4 </SUB>alkyl, C<SUB>1-4 </SUB>alkoxy, C(O)(C<SUB>1-4 </SUB>alkyl), N(C<SUB>1-6 </SUB>alkyl)<SUB>2</SUB>, CF<SUB>3 </SUB>or OCF<SUB>3</SUB>); the process comprising reacting a compound of formula (II): wherein R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as defined above, with a suitable base; and reacting the product so formed with R<SUP>1</SUP>OC(O)CH<SUB>2</SUB>X, wherein R<SUP>1 </SUP>is as defined above and X is chloro, bromo or iodo; wherein the process is carried out in a suitable solvent at a temperature in the range -40° C. to -5° C.; and wherein at least 0.2 moles of the compound of formula (II) are used in the process.
Patent CY-1106912-T1 (CY)
Title: Υδροξυ-υποκατεστημενες 2-αζετιδινονες χρησιμες σαν υποχοληστερολαιμικοι παραγοντες
Inventor: GHOSAL ANIMA
IPC: A61K31/397
Filed: 2007-10-08
Abstract: Υποχοληστερολαιμικές ενώσεις σάκχαρο-υποκατεστημένης 2-αζετιδινόνης του τύπου: αποκαλύπτονται, καθώς επίσης μέθοδος μείωσης της χοληστερόλης με χορήγηση των αναφερθεισών ενώσεων, φαρμακευτικές συνθέσεις που τις περιέχουν και ο συνδυασμός ενός παράγοντα μείωσης της χοληστερόλης σάκχαρο-υποκατεστημένης 2-αζετιδινόνης και ενός αναστολέα βιοσύνθεσης χοληστερόλης για τη θεραπεία και πρόληψη αθηροσκλήρωσης.
Patent CY-1108112-T1 (CY)
Title: Χρηση βακτηριδιων προικισμενων με αποïμιναση αργινινης για να διεγειρεται αποπτωση ή/και να μειωνεται μια φλεγμοnωδης αντιδραση και φαρμακευτικες ή διαιτητικες συνθεσεις που περιεχουν τετοια βακτηριδια
Inventor: DE SIMONE CLAUDIO
IPC: A61K38/50
Filed: 2008-06-03
Abstract: Αποκαλύπτεται η χρήση βακτηριδίων προικισμένων με αποϊμινάση αργινίνης, για να διεγείρεται απόπτωση ή/και να μειώνεται φλεγμονώδης αντίδραση και φαρμακευτικές ή διαιτητικές συνθέσεις που περιέχουν τέτοια βακτηρίδια. Επίσης συμπεριλαμβάνεται ένα στέλεχος Lactobacillus brevis εντόνως προικισμένο με αποϊμινάση αργινίνης.
Patent CY-1108294-T1 (CY)
Inventor: ROBERTSON JOHN FORSYTH RUSSELL
IPC: G01N33/564
Filed: 2008-08-25
Abstract: The invention relates to tumour marker proteins and their preparation from fluids from one or more cancer patients, wherein said fluids are those which collect in a body cavity or space which is naturally occurring or which is the result of cancer or medical intervention for cancer. Exemplary fluids are ascites, pleural effusion, seroma, hydrocoele and wound drainage fluid. The invention also relates to preparation of tumour marker proteins from excretions taken from patients with cancer.  The said tumour marker proteins are useful in cancer detection methods which involve detecting or quantitatively measuring autoantibodies to circulating tumour markers or markers expressed on or in tumour cells and in various research applications. The invention is also directed to such uses.
Patent CY-1109808-T1 (CY)
Inventor: HEINTZELMAN GEOFFREY R
IPC: C07D405/14
Filed: 2009-07-14
Abstract: This invention provides novel arylindenopyridines and arylindenopyrimidines of formula (I), (II) wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
Patent CY-1109750-T1 (CY)
Title: ΔΙΑΛΥΤΗ ΓΛΥΚΟΠΡΩΤΕΪΝΗ ΥΑΛΟΥΡΟΝΙΔΑΣΗΣ (sHASEGP), ΔΙΑΔΙΚΑΣΙΑ ΓΙΑ ΤΗΝ ΠΑΡΑΣΚΕΥΗ ΤΗΣ, ΧΡΗΣΕΙΣ ΚΑΙ ΦΑΡΜΑΚΕΥΤΙΚΕΣ ΣΥΝΘΕΣΕΙΣ ΠΟΥ ΤΗΝ ΠΕΡΙΛΑΜΒΑΝΟΥΝ
Inventor: BOOKBINDER LOUIS H
IPC: A61K47/48
Filed: 2010-01-22
Abstract: Η εφεύρεση αναφέρεται στην ανακάλυψη καινοτόμων διαλυτών ουδέτερων δραστικών Γλυκοπρωτεϊνών Υαλουρονιδάσης (sHASEGP's), μεθόδους για την κατασκευή τους, και στην χρήση τους στην διευκόλυνση της χορήγησης άλλων μορίων ή στην ανακούφιση παθολογικών καταστάσεων που σχετίζονται με τις γλυκοσαμινογλυκάνες. Ελάχιστα δραστικά τμήματα πολυπεπτιδίων των διαλυτών, ουδέτερων δραστικών πεδίων των sHASEGP περιγράφονται, τα οποία περιλαμβάνουν τμήματα σακχάρων που είναι συνδεδεμένα σε ασπαραγινικό που απαιτούνται για ένα λειτουργικό ουδέτερο δραστικό πεδίο υαλουρονιδάσης. Περιλαμβάνονται τροποποιημένες αμινοτελικά καθοδηγητικά πεπτίδια τα οποία ενισχύουν την έκκριση των sHASEGP. Η εφεύρεση περιλαμβάνει επιπλέον σιαλιλυλοποιημένες και πεγκυλιωμένες μορφές μιας ανασυνδυασμένης sHASEGP προκειμένου να ενισχυθεί η σταθερότητα και η φαρμακοκινητική στον ορό στα φυσικώς υπάρχοντα ένζυμα σφαγείου. Περιγράφονται επιπλέον κατάλληλες συνθέσεις μιας ουσιαστικά καθαρής ανασυνδυασμένης sHASEGP γλυκοπρωτεΐνης που προέρχεται από ένα ευκαρυωτικό κύτταρο που παράγει την κατάλληλη γλυκοσυλίωση που απαιτείται για την βέλτιστη απόδοση της.
Patent CY-1113297-T1 (CY)
Title: Μεθοδος παρασκευης αναστολεων νουκλεοζιτικων φωσφορυλασων και νουκλεοζιδασων
Inventor: EVANS GARY BRIAN
IPC: C07H19/23
Filed: 2012-10-05
Abstract: Η παρούσα εφεύρεση αναφέρεται σε μια νέα μέθοδο για την παρασκευή ενώσεων του γενικού τύπου (I) οι οποίες είναι αναστολείς των πουρινο-νουκλεοζιτικών φωσφορυλασών (ΡΝΡ), πουρινο-φωσφοριβοζυλ-τρανσφερασών (PPRT), 5'-μεθυλθειοαδενοσινο-φωσφορυλασών (ΜΤΑΡ), 5'-μεθυλθειοαδενοσινο-νουκλεοζιδασών (ΜΤΑΝ) και/ή νουκλεοζιτικών υδρολασών (ΝΗ). Η παρούσα εφεύρεση αναφέρεται σε μια νέα μέθοδο για την παρασκευή ενώσεων του γενικού τύπου (I) οι οποίες είναι αναστολείς των πουρινο-νουκλεοζιτικών φωσφορυλασών (ΡΝΡ), πουρινο-φωσφοριβοζυλ-τρανσφερασών (PPRT), 5'-μεθυλθειοαδενοσινο-φωσφορυλασών (ΜΤΑΡ), 5'-μεθυλθειοαδενοσινο-νουκλεοζιδασών (ΜΤΑΝ) και/ή νουκλεοζιτικών υδρολασών (ΝΗ).
Patent CY-1115622-T1 (CY)
Title: Εστερες μετρονιδαζολης για αντιμετωπιση ροδοχρου ακμης
Inventor: BOITEAU JEAN-GUY
IPC: C07D233/94
Filed: 2014-10-13
Abstract: Η παρούσα εφεύρεση σχετίζεται με μία ένωση επιλεγμένη από την ένωση του τύπου (Ι) παρακάτω· εναντιομερή αυτής και φαρμακευτικώς αποδεκτά άλατα αυτής, και επίσης με τις χρήσεις αυτής.
Patent CY-1120938-T1 (CY)
Title: Μεθοδος για την κατεργασια ενος υπογειου σχηματισμου
Inventor: KRINS BASTIAAN
IPC: C08L67/04
Filed: 2018-09-26
Abstract: Αποκαλύπτεται μία μέθοδος κατεργασίας ενός υπογείου σχηματισμού σε θερμοκρασίες τουλάχιστον 150°C δια ενός πεπιεσμένου υγρού ρωγμάτωσης που περιλαμβάνει πρόσθετα συγκράτησης ανοιχτών ρωγμών και στερεά πρόσθετα σχηματισμού διαύλων ώστε να δημιουργηθούν ρωγμές στον υπόγειο σχηματισμό, όπου το υγρό ρωγμάτωσης παρασκευάζεται με τη χρήση πρόσθετων σχηματισμού ρωγμών που περιλαμβάνουν στερεά πολυγαλακτικού οξέος (PLA) που παράγονται από ένα μείγμα πολυ L-γαλακτικού οξέος (PLLA) και πολυ D-γαλακτικού οξέος (PDLA).
Patent CY-1122725-T1 (CY)
Title: Αποσμητικη συνθεση που περιλαμβανει ενα μειγμα αλφα, βητα και γαμμα κυκλοδεξτρινων
Inventor: TONGIANI SERENA
IPC: A61K8/73
Filed: 2020-02-27
Abstract: Η εφεύρεση σχετίζεται με μια σύνθεση απορρόφησης οσμών που περιλαμβάνει ένα μείγμα α-, β-, και γ-κυκλοδεξτρινών, όπου η ποσότητα των εν λόγω α-, β-, και γ-κυκλοδεξτρινών ισούται ή είναι μεγαλύτερη από τη συνολική ποσότητα των άλλων δυο κυκλοδεξτρινών.
Patent CY-1124933-T1 (CY)
Title: Κυτταροτοξικες και αντι-μιτωτικες ενωσεις και μεθοδοι χρησης αυτων
Inventor: WINTERS GEOFFREY C
IPC: C07K7/02
Filed: 2022-02-01
Abstract: Αποκαλύπτονται ενώσεις οι οποίες έχουν κυτταροτοξική και/ή αντιμιτωτική δράση. Αποκαλύπτονται επίσης μέθοδοι που σχετίζονται με την παρασκευή και χρήση τέτοιων ενώσεων, καθώς και φαρμακευτικές συνθέσεις που περιλαμβάνουν τέτοιες ενώσεις. Αποκαλύπτονται επίσης συνθέσεις που έχουν τη δομή: (T)-(L)-(D), όπου το (Τ) είναι ένα τμήμα στόχευσης, το (L) είναι ένας προαιρετικός συνδέτης και το (D) είναι μία ένωση η οποία έχει κυτταροτοξική και/ή αντι-μιτωτική δραστικότητα.
Patent HR-P20100524-T1 (HR)
Title: Rifle
Inventor: ROHRAUER HERMANN
IPC: F41C23/16
Filed: 2010-09-24
Abstract: A rifle comprising a housing, a barrel anchored thereon and a forearm extending below the barrel. The barrel is anchored by a fastening element which extends through a cross hole of the housing. The forearm has at least one axial projection that detachably engages into a seat of the housing. The cross hole for anchoring the barrel and the seat for fastening the forearm intersect and the forearm comprises a snap-in recess for the fastening element to snap in when the barrel is anchored.
Patent HR-P20100672-T1 (HR)
Title: Hcv ns5b inhibitors
Inventor: BERGSTROM CARL P
IPC: C07D487/04
Filed: 2010-12-06
Abstract: The invention encompasses compounds of Formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
Patent SI-1504672-T1 (SI)
Title: A process for producing a chocolate snack
Inventor: BUTTINI ROBERTO
IPC: A23G3/54
Filed: 2003-08-08
Abstract: A process for the production of a snack comprising at least a first and a second layer of soft dough with an interposed layer of chocolate, that foresees the steps of depositing on a first continuous layer of oven baked soft dough a continuous layer of a cream with barrier function with regard to the migration of moisture, followed by a continuous layer of melted chocolate incorporating 0.5 to 10% water and by a second continuous layer of oven baked soft dough. Optionally, the above described steps can be repeated for further utilized layers of soft dough, and finally the cutting of the superimposed layers results in single filled snacks.
Patent SI-1546185-T1 (SI)
Title: Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof
Inventor: RATHORE ANURAG S
IPC: C07K14/00
Filed: 2003-08-26
Abstract: The present invention is directed generally to recombinant methods for making a desired polypeptide. These method(s) yield a polypeptide product containing reduced levels of isoform impurities thereof. In particular, the present invention is directed to (1) a recombinant method for preparing growth hormone with reduced isoform impurities thereof and (2) a recombinant method for preparing a growth hormone antagonist, such as pegvisomant, and its protein intermediate, also having reduced isoform impurities thereof. More specifically, the isoform impurities that are decreased by methods of the present invention are the trisulfide and des-phe isoform impurities of growth hormone and growth hormone antagonist (or its intermediate), respectively.
Patent SI-1667746-T1 (SI)
Title: Bioartificial implant and its use and method of reducing the risk for formation of connective tissue after implantation
Inventor: BRUCE ADAM
IPC: A61F2/00
Filed: 2004-10-04
Abstract: A bioartificial implant comprises a semipermeable barrier designed from one side to allow diffusion or prevent diffusion of predetermined substances/materials/molecules/cells/cell lines produced in the human body to the other opposite side of the barrier, and from said other opposite side to allow diffusion or prevent diffusion of predetermined substances which are the same as or different from the first mentioned substances/materials/molecules/cells/cell lines. The semipermeable barrier has a surface coating at least on said one side a bioactive metal, such as titanium, which surface coating is permeable to allow said diffusions. In a method for reducing the risk of formation/growth of connective tissue in connection with an implant which comprises a semipermeable barrier, the barrier is provided at least on one side with a permeable coating of bioactive metal. An example of the use of the implant is bioartificial pancreas.
Patent SI-1606282-T1 (SI)
Title: Phenyl- and pyridylpipereidinye-derivatives as modulators of glucose metabolism
Inventor: JONES ROBERT M
IPC: A61K31/00
Filed: 2004-02-23
Abstract: The present invention relates to certain substituted aryl and heteroaryl derivatives as shown in Formula (Ia) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.
Patent SI-2070530-T1 (SI)
Title: Treatment of diseases associated with the use of antibiotics
Inventor: SHUE YOUE-KONG
IPC: A61P1/00
Filed: 2005-05-13
Abstract: The invention relates to a compound having formula (II), a pharmaceutical composition comprising the compound and the compound for use in treating or preventing a disease in a patient caused by the presence of  Clostridium difficile,  methicillin-resistant  Staphylococcus aureus  (MRSA) or vancomycin-resistant enterococci (VRE).
Patent SI-1935213-T1 (SI)
Title: Method for operating an induction heating device
Inventor: SCHILLING WILFRIED
IPC: H05B6/00
Filed: 2006-10-13
Abstract: The invention relates to a method for operating an induction heating device. The induction heating device comprises an induction coil and a frequency converter for producing a control voltage for the induction coil. The frequency converter comprises a rectifier rectifying an alternating supply voltage (UN), an intermediate circuit capacitor, looped in between output terminals of the rectifier and equalizing the rectified voltage (UG), and at least one controllable switching element, looped in between the output terminals of the rectifier. According to the invention, in a predetermined discharge interval (INT) before a zero crossing (ND) of the alternating supply voltage (UN), the intermediate circuit capacitor is discharged to a threshold value by controlling the at least one switching element before the induction coil is controlled in order to produce an adjustable heating capacity.
Patent SI-1854386-T1 (SI)
Title: Beverage preparing machine and method for using a beverage preparing machine
Inventor: REYHANLOO SHAHRYAR
IPC: A47J31/00
Filed: 2006-05-12
Abstract: The machine (1) has a power supply (10) with an electric circuit (11) for supplying a functional unit (6) and a control unit (5) with current (I), where the circuit has a switch (15) with switch contacts (20, 25) and an operating element (16). A sensing unit (30) e.g. touch sensitive sensor, interacts with the unit (5) for registering operations of the element. The unit (5) assumes an operating state in which a control signal is provided so that the contact (25) assumes a closed state after the operation of the element, and assumes an open state after another operation of the element. An independent claim is also included for a method of operating a beverage preparation machine for preparing and dispensing a beverage.
Patent SI-1881845-T1 (SI)
Title: Nipah virus vaccines
Inventor: AUDONNET JEAN CHRISTOPHE FRANCIS
IPC: A61K39/00
Filed: 2006-04-14
Abstract: The present invention relates to recombinant anti-Nipah virus vaccines and the administration of such vaccines to animals, advantageously pigs. Advantageously, the anti- Nipah virus vaccine may comprise a recombinant avipox virus containing a Nipah virus glycoprotein gene. The invention encompasses methods of vaccinating animals, advantageously pigs, by administration of anti-Nipah virus vaccines that may comprise a recombinant avipox virus that may contain a Nipah virus glycoprotein gene.
Patent SI-2121146-T1 (SI)
Title: Coloured playing bowl
Inventor: DATA GIANCARLO
IPC: A63B37/00
Filed: 2007-03-21
Abstract: A game bowl is disclosed, comprising an internal core covered with an external shell made of plastic material.
Patent SI-2091799-T1 (SI)
Title: Device for the contactless determination of the energy requirements of a point actuating drive
Inventor: TAFEIT DIETMAR
IPC: B61L5/00
Filed: 2008-01-17
Abstract: The invention relates to a device for the contactless determination of the energy requirements of a point actuating drive (7), comprising asynchronous motors which are connected to a three-phase current source (1) via conductors. According to the invention, at least one inductance coil is mounted in parallel to a phase conductor and the conductor that is connected to the inductance coil is guided in the opposite direction at or through a sensor (5), wherein the blind current component produced in the throttle (4) compensates at least partially the blind current component that is, in addition to the effective power component, contained in the line which is guided via the motor winding.
Patent SI-2135738-T1 (SI)
Title: Method of conditioning an absorptive material in a laminate
Inventor: HOMBACH FRANZ PETER
IPC: B32B15/08
Filed: 2008-06-20
Abstract: Laminate (10) comprises: a barrier layer (24) as barrier against water vapor and gas; an outer layer (20) made from polyamide, arranged on one side of the barrier layer; a moisture absorbing absorber material (32) arranged on the second side of the barrier layer; and sealable inner layer (28) uncovering the absorber material, arranged on the second side of the barrier layer, where the laminate exhibits a given moisture ratio for preconditioning the absorber material. An independent claim is included for a procedure for adjusting the moisture ratio of a moisture absorbing material in the laminate available in the form of a band, comprising providing the laminate with water for the absorption of water in the outer layer made of polyamide.
Patent SI-2170739-T1 (SI)
Title: Bag for transporting and handling liquid or quasi liquid substances
Inventor: SCHINASI PIERO
IPC: B65D88/00
Filed: 2008-07-16
Abstract: The invention relates to a bag for transporting and handling liquid or quasi liquid substances, that comprises at least a bottom and four sides and optionally a lid. The bag is provided with a sealed inner envelope including filling and optionally draining members. The bag also includes reinforcement plates integrated in the sides and the lid of the bag and optionally in the bottom of the bag. The bag is further provided with members for lifting same. The bag is particularly characterised in that the four sides of the bag include at the upper portions thereof an overhanging collar (2) oriented towards the inside, the four tails of the collar being connected at their adjacent edges along common ridges (3) oriented as in a pyramid, and in that the lifting members include, on the one hand, lifting straps (7) including a section (7d) sawn on the above-mentioned ridges (3) of the collar so that each strap, also sawn on the vertical ridges of the four corners of the bag (7a), includes a section (7d) oriented back into the bag along said ridge (3) and, on the other hand, a tube or duct (8) connected at least to the straps grouped by pairs.
Patent SI-2610278-T1 (SI)
Title: Curable composition comprising a polymer bearing at least one hydrolysable organo-oxy-silyl group
Inventor: STENERT MICHAEL DR
IPC: C09J201/00
Filed: 2011-12-30
Abstract: Curable composition comprises (a) at least one polymer comprising at least one hydrolyzable organo-oxy-silyl group, (b) at least one first silane compound (I), (II), or (III), (c) at least one second silane compound (IV), (V), or (VI) different from the first silane compound. The component (b) is a primary amine, and the component (c) is a secondary or tertiary amine. Curable composition comprises (a) at least one polymer comprising at least one hydrolyzable organo-oxy-silyl group, (b) at least one silane compound of formula (R1R2N-(CH) 2) a-(CR3R4) b-(CH 2) c-SiR5 3-d(OR6) d) (I), (R1R2N-(CH 2) a-(CR3R4) b-(CH 2) c-SiR5(OR6)(O R7) (II), or (R1R2N-(CH 2) a-(CR3R4) b-(CH 2) c-Si(OR6)(OR7)(OR8) (III), (c) at least one silane compound of formula (R9N8-(CH 2) f-(CR11R10) g-(CH 2) h-SiR11 3-i(OR14) i) (IV), (R7R10N-(CH 2) f-(CR11R10) g-(CH 2) h-SiR13(OR14)(OR15) (V), or (R7R8N-(CH 2) f-(CR11R10) g-(CH 2) h-Si(OR12)(OR15)(OR16) (VI) different from the component (b). The component (b) is a primary amine, and the component (d) is a secondary or tertiary amine. R6-R8 : alkyl of formula (-C nH 2n+1), alkoxyalkyl of formula (-C nH 2n-O-C nH 2n+1), or alkoxyalkyl of formula (-C nH 2n-O-C n+1H 2n+3); R12, R15, R16 : alkyl of formula (-C n+1H 2n+3), or alkoxyalkyl of formula (-C n+1H 2n+2-O-C nH 2n+1), (-C n+1H 2n+2-O-C n+1H 2n+3), or (-C nH 2n-OC n+2H 2n+5); R1, R7 : H or 1-15C alkyl(optionally branched or cyclic), -primary amino-alkyl, secondary-amino-alkyl, aryl, or alkenyl; R2, R10 : H or 1-10C alkyl(optionally branched or cyclic) primary amino-alkyl, secondary-amino-alkyl, aryl, or alkenyl; R3, R4, R11, R10 : H, 1-15C alkyl, 1-15C cycloalkyl, 1-15C alkenyl or 1-15C aryl; R5, R13 : 1-10C alkyl; a, b, c, f, g, h, d, i : 0-3; and n : 1-6. Provided that: d is >= i.
Patent SI-2678351-T1 (SI)
Title: Hiv gp-120 variant
Inventor: YUSTE HERRANZ MARIA ELOISA
IPC: C12N15/00
Filed: 2012-02-24
Abstract: The invention relates to a method for rapid immunogen selection (RIS) based on the binding a library of recombinant viruses containing randomized HIV gp120 variants of a surface polypeptide displayed to said neutralizing antibodies. The invention relates as well to the use of the HIV gp120 immunogens isolated according to the RIS method of the invention in medicine for the treatment of diseases caused by a virus and in diagnosis for the identification of neutralizing antibodies in a patient.
Patent SI-2859389-T1 (SI)
Title: Short- to long-term temperature forecasting system for the production, management and sale of energy resources
Inventor: GIUNTA GIUSEPPE
IPC: G06Q10/00
Filed: 2013-06-11
Abstract: A method is described for the weather-climatic temperature forecasting, from short to long term, comprising the phases of acquiring meteorological parameters of a large-scale (SG) geographical area having a pre-determined amplitude; decomposing the large-scale geographical area (SG) into a base area and a regional area (SR); determining the temperature close to the surface of the base area, starting from the parameters available on the large-scale geographical area (SG), using an empirical-statistical model (statistical down-scaling); determining the tendencies of the meteorological parameters in the regional area (SR), starting from the meteorological parameters available on the large-scale geographical area (SG), using a dynamic numerical model (dynamic down-scaling); performing the combination (ensemble down-scaling), through an applicative model, of the empirical- statistical model (statistical down-scaling) and the dynamic numerical model (dynamic down-scaling) to obtain in continuous, from short term to seasonal term, the temperature forecast close to the surface. The applicative model adds a statistical scaling of the data for temperatures close to the surface which are therefore re-assimilated in the regional area (SR) as new temperature values close to the physical boundary of the regional area (SR), introducing, during the dynamic down-scaling phase, a range of pseudo- observations, which properly act on the regional area (SR). In this way, during the dynamic down-scaling phase, a reconstructed range of observations is introduced, de facto, which are on a spatial scale compatible with that of the regional model.