baber/WOPTO huggingface dataset:
Patent DE-60324331-D1 (DE)
Inventor: BUENEMANN MORITZ
IPC: G01N33/542
Filed: 2003-12-19
Granted: 2008-12-04
Abstract: The present invention relates to recombinant seven-transmembrane receptor, whereby the amino terminus of said recombinant receptor is located on an extracellular side and the carboxy-terminus is located on an intracellular side of a membrane, comprising at least two detectable labels, whereby a first of said at least two detectable labels is or is located on the carboxy-terminus and whereby a second of said at least two labels is or is located on the first or third intracellular loop or whereby a first of said at least two labels is or is located on the third intracellular loop. Furthermore, nucleic acid molecules encoding said recombinant seven-transmembrane receptors are described as well as vector and host cells comprising the same. Furthermore, the present invention provides for identification and screening methods for molecules or compounds which are capable of modifying the biological end of pharmacological function of seven-transmembrane receptor proteins. Finally, diagnostic compositions comprising the compounds of the present invention as well as kits comprising said compounds are disclosed.
Patent DE-60325807-D1 (DE)
Inventor: JONCKHEERE MARC R M
IPC: F16H55/56
Filed: 2003-06-19
Granted: 2009-03-05
Abstract: A crop processing machine such as a threshing machine (10) comprises a variable speed drive transmission for driving the crop processing means (308) through a range of speeds. The drive transmission comprises a plurality of parallel shafts (17, 31, 304) and an input wheel (16) connected to a first shaft (17) on a first side of said machine (10). A variable pitch drive transmission arrangement (34) on the first side of said machine is drivingly connected between said input wheel (16) and said crop processing means (308). It comprises a first variable transmission device (40) connected to the first shaft (17) for driving a first drive belt (32) and a second variable transmission device (200) connected to a second said shaft (31) and being driven said first drive belt (32). A first fixed pitch drive wheel (320) is connected to said second shaft (31) on a second, opposite side of said machine and powers a second drive belt (322). A second fixed pitch drive wheel (324) is connected to a third shaft (304) on said second side of the machine and is driven by said second drive belt (322) for powering said crop processing means (308). The transmission on the second side of the machine is readily accessible for replacing or interchanging the drive wheels (320, 324) in order to realise different transmission ratios. <IMAGE>
Patent DE-60325830-D1 (DE)
Inventor: SHODA MOTOSHI
IPC: A61P37/08
Filed: 2003-02-20
Granted: 2009-03-05
Abstract: A compound represented by the formula (I) or a salt thereof <CHEM> wherein n represents an integer of 1 to 3, R represents an alkyl group having 3 to 8 carbon atoms, a group represented by the following formula: R<1>(CH2)k- (wherein k represents 0 or an integer of 1 to 3; R<1> represents a saturated cyclic alkyl group having 3 to 7 carbon atoms or a saturated condensed cyclic alkyl group having 6 to 8 carbon atoms, and the group R<1> may be substituted with a lower alkyl group having 1 to 4 carbon atoms) and the like, and Ar represents a condensed bicyclic group such as naphthalen-1-yl group, which has suppressing action on prostaglandin and leukotriene production and is useful for prophylactic and/or therapeutic treatment of various inflammatory diseases and the like caused by these lipid mediators.
Patent DE-60329342-D1 (DE)
Inventor: GROBBEL THOMAS MICHAEL
IPC: B23B31/36
Filed: 2003-01-02
Granted: 2009-11-05
Abstract: An equalizing chuck assembly (10) for heavy duty application includes a chucking assembly having a plurality of rocker arms (18) operably connected to an actuator (14) by a plurality of toggle links (60). Jaw members (20) are disposed on one end of the rocker arms (18) and a counterweight (22) is disposed on an opposite end of the rocker arms (18). The equalizing chuck assembly (10) utilizes a plurality of equalizing plates (52) interconnected between the actuator (14) and the rocker arm (18) to provide a degree of adjustment to accommodate eccentricities within the workpiece to be held by the chucking assembly (10). <IMAGE>
Patent DE-68900972-D1 (DE)
Inventor: VAN ROOIJ JACOBUS HUBERTUS MAR
IPC: F16G5/18
Filed: 1989-10-04
Granted: 1992-04-16
Abstract: Transmission chain for a cone pulley drive with intercoupled links (2a...2c) and pivot pins (4a, 4b) inserted through link openings, the end surfaces of which cooperate with the cone surfaces, and where between each pivot pin (4a, 4b), on the one hand, and the opposite-lying upright opening sides of a number of adjacent links, on the other, an intermediate piece (6a...6d) with rolling contact action is inserted whose first longitudinal side (12) is coupled to the link opening side and of which the oppposite-lying second longitudinal surface (10) forms the rolling contact surface cooperates with the longitudinal side of the pin, a number of grooves (24) running between the first and the second longitudinal side being formed in each intermediate piece (10) in at least the narrow longitudinal side facing the inside of the chain.
Patent DE-68904578-D1 (DE)
Inventor: MATSUO HISAYUKI
IPC: C12N9/02
Filed: 1989-03-13
Granted: 1993-03-11
Abstract: A C-terminal  alpha -amidating enzyme of porcine origin having the following properties: (1) Action and substrate specificity: acting on a peptide or protein represented by the formula, X-R-Gly wherein Gly represents a C-terminal glycine residue, R represents an amino acid residue to be  alpha -amidated and X represents a remaining portion of the peptide or protein to convert it to a peptide or protein represent by the formula X-R-NH2 wherein R-NH2 represents a C-terminal  alpha -amidated amino acid residue and X represents a residual portion of the peptide or protein; (2) optimum pH: 6.5 to 8.5; (3) molecular weight: about 92,000 as determined by SDS-polyacrylamide gel electrophoresis; and (4) containing the following peptide fragment: ...Glu-Ala-Pro-Leu-Leu-Ile-Leu-Gly....; and a process for the production of the C-terminal  alpha -amidating enzyme comprising the step of extracting and purifying the enzyme from porcine atrium cordis exhibiting the enzyme activity.
Patent DE-68913464-D1 (DE)
Inventor: GIARDINI GIORGIO
IPC: H02H3/33
Filed: 1989-11-23
Granted: 1994-04-07
Abstract: The present invention relates to an emergency remote opening device, particularly for differential switches, comprising a core (10) of ferromagnetic material on which a first and a second winding (11, 12) are wound; in normal operating conditions, the windings generate magnetic fluxes which compensate each other. At least one normally-closed opening button (20) is arranged in series with at least one of the windings. A secondary winding (30) furthermore concatenates the flux generated by the first and second windings and drives a circuit-breaking actuator (31).
Patent DE-68916027-D1 (DE)
Inventor: OLSON LYNNE
IPC: D06P5/00
Filed: 1989-07-28
Granted: 1994-07-14
Abstract: Aqueous processes and compositions of the invention for obtaining a "stone-washed", distressed or "used and abused" look in clothing, particularly in the panels and seams of denim jeans and jackets involve compositions that are stone-free that avoid mechanical abrasion of the fabric. In particular, the process and composition of the invention used to obtain the distressed, "stone-washed" or "acid washed look" are free of common pumice or pumice-bleach compositions, used in large institutional-size laundry machines, and rely solely on the chemical action of aqueous treatment compositions. The aqueous treatments can be made from liquid or solid concentrates.
Patent DE-68923430-D1 (DE)
Inventor: FREYNE EDDY JEAN EDGARD
IPC: C07D403/14
Filed: 1989-11-28
Granted: 1995-08-17
Abstract: Novel (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives of formula <CHEM> the pharmaceutical acceptable acid addition salts thereof and the stereochemically isomeric forms thereof, wherein -X<1>=X<2>- is -CH=CH-, -CH=N-, or -N=CH-; R is hydrogen or C1-6alkyl; Y is hydrogen, C1-10alkyl, C3-7cycloalkyl, Ar<1>, Ar<2>-C1-6alkyl, C2-6alkenyl or C2-6alkynyl;  Z is a radical of formula <CHEM>   <CHEM> which compounds are useful for treating disorders which are characterized by an excessive proliferation and/or abnormal differentiation of epithelial tissues: pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent DE-69007239-D1 (DE)
Inventor: CLAUSS GILLES
IPC: G01D5/26
Filed: 1990-11-19
Granted: 1994-04-14
Abstract: The present invention relates to a sensor for direction and amplitude of a displacement, comprising a mirror solidly connected to a movable element and a photo emitter/photo receiver assembly solidly connected to a fixed reference point. This assembly comprises a central optical fibre (1) emitting a cone of light towards the mirror (10) and receiving optical fibres (2 to 7). The mirror is circular and its diameter and its axial distance from the end of the fibres are such that in the aligned position, its diameter corresponds substantially to that of the cone of light (11) emitted by the central fibre and that the reflected cone of light (12) is substantially tangential to the external radial edges of the receiving fibres. The mirror (10) is mounted on the outermost transverse wall (22) of a tube (21), perpendicularly to the axis of this tube and in an aligned manner, the other end of this tube being fitted into a base (20), the optical fibres (1 to 7) having their ends inside the said tube and facing the mirror. <IMAGE>
Patent DE-69009052-D1 (DE)
Inventor: SMITH MARK
IPC: A61F13/00
Filed: 1990-03-16
Granted: 1994-06-23
Abstract: An absorbent device which comprises an absorbent layer having an apertured contoured polymer film attached to a surface, wherein this surface is provided with a plurality of depressions which communicate directly with the apertures in the film. The device may be produced by separating the polymer film and a carrier material which have been formed into a laminate having impressed therein raised areas defining, for example, the strands of net and depressed areas such that upon separation the depressed areas of the film remain attached together with associated portions of the attached absorbent, to the carrier, leaving the raised areas attached to the remainder of the absorbent.
Patent DE-69019726-D1 (DE)
Inventor: DAIKUZONO NORIO
IPC: A61B18/20
Filed: 1990-08-31
Granted: 1995-06-29
Abstract: USE : For applying laser beams to tissue of human or animal to perform incision, transpiration or thermotherapy, and for use when expanding constricted part caused by cholesterol in narrow passage in organic tissue e.g. blood vessel. @(33pp Dwg.No.1,2/13)@.
Patent DE-69034114-D1 (DE)
Inventor: SHIRAKI SHIGEMI
IPC: C08G63/85
Filed: 1990-03-21
Granted: 2003-12-11
Abstract: The present invention is directed to a polyethylene terephthalate chip, obtainable by a process comprising liquid phase polycondensation of an esterification product, solid phase polycondensation of the product obtained and subsequently contacting the product of the solid phase polycondensation with hot water or water vapour. The polycondensation rate is small, and the content of cyclic trimers is low.
Patent DE-69104083-D1 (DE)
Inventor: MURAKAMI KIYOKAZU
IPC: A61P15/00
Filed: 1991-02-21
Granted: 1994-10-27
Abstract: There are provided 4,5-dihydroxy-2,6,6-trimethyl-2-cyclohepten-1-one and/or the individual stereoisomers thereof, a process for its preparation, an antiulcer agent in the form of a pharmaceutical composition containing it as an effective ingredient, and its use in the preparation of such a composition.
Patent DE-69108455-D1 (DE)
Inventor: NAKATSUGAWA TOMOMI
IPC: B41M5/52
Filed: 1991-06-07
Granted: 1995-05-04
Abstract: A recording medium comprises basic magnesium carbonate and a magnesium salt of silicic acid or of phosphorus oxy-acid. Ink-jet recording is conducted using the recording medium to obtain high image density without any problem such as indoor discoloration, white haze, fattening of letters, etc.
Patent DE-69109297-D1 (DE)
Inventor: YESAIR DAVID W
IPC: A61K47/24
Filed: 1991-08-12
Granted: 1995-06-01
Abstract: A composition is disclosed containing non-esterified fatty acids having 14-18 carbon atoms, monoglycerides which are monoesters of glycerol and fatty acids having 14-18 carbon atoms, lysophosphatidylcholine in which the fatty acid moiety has 14-18 carbon atoms and bicarbonate. The compositions can optionally also contain bile salts. These compositions form submicron size colloidal particles and can act as vehicles for transporting orally administered drugs, sources of calories in the form of readily absorbable fats and as particles for topical application to the skin. A method of making these particles is also described.
Patent DE-69111732-D1 (DE)
Inventor: GEORGE ERIC RICHARD
IPC: C08L73/00
Filed: 1991-09-25
Granted: 1995-09-07
Abstract: Polymer composition comprising a linear alternating polymer of carbon monoxide and at least one ethylenically unsaturated compound, and as a melt stabilising additive, a hydroxyapatite.
Patent DE-69112150-D1 (DE)
Inventor: KAWAGUCHI TAKAHISA
IPC: B29C48/09
Filed: 1991-04-09
Granted: 1995-09-21
Abstract: A bent pipe forming apparatus for extruding and forming a fluid material into an annular member having a central mandrel (22) and a die (21) defining an annular gap between the mandrel (22) and the die (21), wherein one of the mandrel (22) and the die (21) is supported to move in a direction perpendicular to an axis of the mandrel (22). The movable mandrel (22) or die (21) is provided on its outer periphery with a guide circular surface (XX) integral therewith. An inner movable ring (4) having inner and outer circular peripheries eccentric to each other is rotatably fitted on the guide surface. An outer movable ring (5) having inner and outer circular peripheries eccentric to each other is rotatably fitted on the periphery of the inner movable ring (4). The outer movable ring (5) is provided with an outer circular peripheries which is rotatably fitted in a stationary circular guide surface (YY). Driving motors (12a, 12b) are provided to independently move the inner and outer movable rings (4, 5). <IMAGE>
Patent DE-69113415-D1 (DE)
Inventor: DURANA MIROSLAV
IPC: G01D5/36
Filed: 1991-11-30
Granted: 1995-11-02
Abstract: The sensor comprises an optoelectronic probe unit (3) and a transparent gauge (2) with two parallel graduated tracks (4, 5). One track (5) has a constant pitch incremental graduation and the other track (4) has a pseudo-random graduation forming binary coding bits constituting a continuous series of words which are different from one another, the width of a bit being a function of the pitch of the incremental graduation. The incremental track (5) is read through a probe reticule (9) by photodetectors (8) which are phase-shifted by 90 DEG  electrically in order to permit interpolation into the pitch of this track. The track (4) with pseudo-random graduation is read by a CCD detector (11) through an image-magnifying lens (13). The signals generated are processed by circuits (15a, 15b) combining the information extracted from the two tracks of the gauge. 
<IMAGE>
Patent DE-69124088-D1 (DE)
Inventor: DEPERNET DOMINIQUE
IPC: C07B57/00
Filed: 1991-11-15
Granted: 1997-02-20
Abstract: PCT No. PCT/FR91/00906 Sec. 371 Date Jul. 21, 1992 Sec. 102(e) Date Jul. 21, 1992 PCT Filed Nov. 15, 1991 PCT Pub. No. WO92/08702 PCT Pub. Date May 29, 1992.Method of resolution of chiral hydantoins of the general formula I    <IMAGE>  (I)  in which: R1 designates a lower alkyl radical comprising 1 to 5 carbon atoms in linear or branched chain, R2 designates a phenyl radical, possibly mono-, di-, or tri-substituted by lower alkyl or alkoxy radicals or halogen atoms, whether identical of different, or a heteroaryl radical containing a ring of 5 to 7 members in which the sole hetero atom is nitrogen, oxygen or sulfur, or else an aralkyl radical the alkyl part of which comprises one or two carbon atoms and the aryl ring is a phenyl group possibly mono-, di- or tri-substituted by radicals which are lower alkyl or alkoxy radicals or halogen atoms, whether identical or different. The hydantoin (I) to be resolved is dissolved in an alcohol or an alkaline solution, and an enantiomer of  alpha -methylbenzyl-amine is added in a defined proportion to the solution obtained, whereupon the diastereoisomeric salt obtained is isolated and treated with an acid solution in order to crystallize the enantiomer of hydantoin (I).
Patent DE-69124489-D1 (DE)
Inventor: MONTAGNE MARC HENRI
IPC: D04H3/04
Filed: 1991-11-25
Granted: 1997-03-13
Abstract: In order to manufacture an impervious composite including an internal reinforcement intended, especially, for the manufacture of aerostatic balloons, a non-woven reinforcement (10), formed from weft yarns and warp yarns which are disposed in two superposed layers, is produced. A covering film (16a, 16b) is applied to each of the faces of this reinforcement with a predetermined force after having brought this film to its temperature for pasty melting on a heating drum (30a, 30b). The non-woven nature of the reinforcement enables the imperviousness of the covering films to be maintained during the formation of the composite. In addition, the formation of small loops on the edges of the composite thus obtained enables connection cables to be inserted which makes it easier for the stresses to be taken up.   <IMAGE>
Patent DE-69126011-D1 (DE)
Inventor: PETTIT GEORGE R
IPC: A61P43/00
Filed: 1991-12-12
Granted: 1997-06-12
Abstract: Bryostatin 2 is converted to bryostatin 1 by a selective protection and deprotection strategy involving the C-26 hydroxyl group.
Patent DE-69130521-D1 (DE)
Inventor: DUDITS DENES DR
IPC: A01H5/10
Filed: 1991-06-18
Granted: 1999-01-07
Abstract: Protoplasts which regenerate reproducibly in a short time to normal, fertile plants can be regenerated from an auxin-autotrophic genotype of Zea mays (L.).
Patent DE-69131362-D1 (DE)
Inventor: IKEDA KAZUE
IPC: B41J2/165
Filed: 1991-02-25
Granted: 1999-07-29
Abstract: An ink jet recording apparatus records information by ejecting ink droplets onto a recording medium (63). The ink jet recording apparatus has a recording head (101H); driving circuits (51), measuring circuit (53), and a judging unit (50). The recording head (101H) has ejection outlets (5) and ink liquid passages (4) connecting to the ejection outlets (5) respectively, an electro-thermal converting element (7) being disposed in each of the ink liquid passages (4), for generating thermal energy for ejecting the ink droplets. The driving circuits (51) drive the electro-thermal converting element (7) to generate the thermal energy enough to eject the ink droplet. The measuring circuit (53) individually measures a resistance value of the electro-thermal converting element (7) when the driving circuits (51) drive the electro-thermal converting element (7). The judging unit (50) judges presence of an abnormal state in the ink liquid passage (4) according to the resistance value. <IMAGE>
Patent DE-69201789-D1 (DE)
Inventor: HENRIKSEN KARSTEN
IPC: C02F11/12
Filed: 1992-01-22
Granted: 1995-04-27
Abstract: Liquid manure is separated into a thick slurry phase and an aqueous phase by a method wherein the manure in a first treatment stepis sedimented into a thick slurry phase containing the coarse solid matter components of the liquid manure and a primary aqueous phase, which is filtrated and discharged as aqueous phase with high N-content, when desired, or, passed to a second treatment step where it is mixed with a flocculant, and flocculated and sedimented into a secondary thick slurry phase, which is united with the thick slurry phase formed in the first treatment step, and a secondary aqueous phase, which is discharged as aqueous phase with moderate N-content, when desired, or passed to a third treatment step where it is subjected to ion exchange with a cation exchanger and discharged as aqueous phase with low N-content. The thick slurry phase is discharged from the first sedimentation step.
Patent DE-69202732-D1 (DE)
Inventor: VAN DAM JAN
IPC: A01D31/00
Filed: 1992-06-23
Granted: 1995-07-06
Abstract: Device for lifting plants such as conifers. It comprises a frame (Z) and a carrier (8) which is displaceable thereon. A support (20) is connected to the carrier by means of a rotary bearing (21). Fixed to said support is an approximately vertically extending arm (15), on the other end of which a curved spade (27) is fitted. A continuous cut is made in the ground with the spade in various stages by rotating the support relative to the carrier, so that the conifer can be removed. <IMAGE>
Patent DE-69203797-D1 (DE)
Inventor: MORRISSEY MICHAEL M
IPC: A61K31/166
Filed: 1992-06-02
Granted: 1995-09-07
Abstract: The invention relates to the compounds of the formula <CHEM>  and pharmaceutically acceptable salts thereof, in which: R1 is amino which is mono- or disubstituted by a substituent selected from an aliphatic hydrocarbon radical, an araliphatic hydrocarbon radical, an aromatic radical, and a cycloaliphatic hydrocarbon radical or is amino which is disubstituted by a divalent aliphatic hydrocarbon radical; R2 is hydrogen, halogen, trifluoromethyl, an aliphatic hydrocarbon radical, or is hydroxy which is etherified by an aliphatic alcohol, araliphatic alcohol, or aromatic alcohol or which is esterified by an aliphatic or araliphatic carboxylic acid; R3 is hydrogen or an acyl radical which is derived from an organic carbonic acid, un organic carboxylic acid, a sulfonic acid, or a carbamic acid; X1 and X3, independently of one another, are oxygen (-O-) or sulphur (-S-); and X2 is a divalent aliphatic hydrocarbon radical which may be interrupted by an aromatic radical; wherein the phenyl rings of formula I may be, independently of one another, further substituted by one or more substituents selected from halogen, trifluoromethyl, un aliphatic hydrocarbon radical, hydroxy, and hydroxy which is etherified by an aliphatic alcohol or which is esterified by an aliphatic or araliphatic carboxylic acid; wherein aryl in the above definitions may be, independently of one another, further substituted by one or more substituents selected from halogen, trifluoromethyl, un aliphatic hydrocarbon radical, hydroxy, and hydroxy which is etherified by an aliphatic alcohol or which is esterified by an aliphatic or araliphatic carboxylic acid; wherein a cycloaliphatic hydrocarbon radical may be substituted by an aliphatic radical. The compounds are useful as selective LTB-4 receptor antagonists in the treatment of conditions or syndromes in mammals which are responsive to LTB-4 receptor antagonism.
Patent DE-69206234-D1 (DE)
Inventor: NORTON HARRY WILLIAM
IPC: B25H1/00
Filed: 1992-08-28
Granted: 1996-01-04
Abstract: A foldable/stowable support apparatus for mounting a hand holdable machine such as a drill or the like in such manner that when the drill or the like is in use the operational axis of the drill or the like is located at a required position and orientation with respect to a surface to be drilled or otherwise machined. The apparatus incorporates a support column (2) and support elements (9,10) pivotable between a closed/stowed position and a support column supporting positon which enables the support column (2) to mount a machine for use in corners of a room or the like. Arrangements (29) are provided for enabling the fine positional adjustment of the machine lengthwise of the support column, and for enabling automatic machine operation cut-off on completion of a predetermined extent of machine operation such as the drilling of a hole of a particular predetermined depth. <IMAGE>