baber/WOPTO huggingface dataset:
Patent EP-1198586-A4 (EP)
Title: An in vivo library-versus-library selection of optimized protein-protein interactions
Inventor: MICHNICK STEPHEN W
IPC: C12Q1/32
Filed: 2000-06-26
Abstract: The present invention describes a rapid and efficient <i>in vivo</i> library-<i>versus</i>-library screening strategy for identifying optimally interacting pairs of heterodimerizing polypeptides. It allows for the screening of a protein library against a second protein library, rather than against a single bait protein, and thus has numerous applications in the study of protein-protein interactions. Additionally, it allows for the application of different selection stringencies. Two leucine zipper libraries, semi-randomized at the positions adjacent to the hydrophobic core, were genetically fused to either one of two designed fragments of the enzyme murine dihydrofolate reductase (mDHFR), and cotransformed into <i>E. coli.</i> Interaction between the library polypeptides was required for reconstitution of the enzymatic activity of mDHFR, allowing bacterial growth. Analysis of the resulting colonies revealed important biases in the zipper sequences relative to the original libraries, which are consistent with selection for stable, heterodimerizing pairs. Using more weakly associating mDHFR fragments, we increased the stringency of selection. We enriched the best performing leucine zipper pairs by multiple passaging of the pooled, selected colonies in liquid culture, as the best pairs allowed for better bacterial propagation. This competitive growth allowed small differences among the pairs to be amplified, and different sequence positions were enriched at different rates. We applied these selection processes to a library-<i>versus</i>-library sample of 2.0 x 10<6> combinations, and selected a novel leucine zipper pair which may be appropriate for use in further <i>in vivo</i> heterodimerization strategies.
Patent EP-1200244-A4 (EP)
Title: Improved conductivity fuel cell collector plate and method of fabrication
Inventor: BRAUN JAMES C
IPC: H01M8/02
Filed: 2000-07-10
Abstract: An improved method of manufacturing a PEM fuel cell collector plate is disclosed. During molding a highly conductive polymer composite is formed having a relatively high polymer concentration along its external surfaces. After molding the polymer rich layer is removed from the land areas by machining, grinding or similar process. This layer removal results in increased overall conductivity of the molded collector plate. The polymer rich surface remains in the collector plate channels, providing increased mechanical strength and other benefits to the channels. The improved method also permits greater mold cavity thickness providing a number of advantages during the molding process.
Patent EP-1242508-A4 (EP)
Title: Method to decrease corrosiveness of reactants in poly(arylene sulfide) polymer production
Inventor: VIDAURRI FERNANDO C JR
IPC: C08G75/02
Filed: 2000-12-27
Abstract: A process is provided for producing a poly(arylene sulfide) polymer in which polymerization reactants comprising an aqueous alkali metal hydroxide and a polar organic compound are pre-reacted at a first temperature to form a mixture, then the mixture is reacted with a sulfur source at a second temperature under conditions sufficient to remove at least a portion of the water that is contained in the mixture, thereafter the thus dehydrated mixture is contacted with at least one dihaloaromatic compound under polymerization conditions.
Patent EP-1239901-A4 (EP)
Title: Torquable guiding member system
Inventor: JACOBSEN STEPHEN C
IPC: A61M25/00
Filed: 2000-12-22
Abstract: A catheter guidewire includes an elongate solid body about which a catheter may be threaded for guidance to a target location in a vasculature passageway of a body. The elongate body includes a proximal end and a distal end, with the distal end being curved. Cuts are formed either by saw-cutting, laser cutting or etching at spaced-apart locations along the length of the body to increase its lateral flexibility. Integral beams are also formed within the body to maintain its torsional strength. The relative location and size of cuts and beams may be selectively adjusted so as to control the direction and degree of flexure, and the change in torsional stiffness relative to flexibility.
Patent EP-1261287-A4 (EP)
Title: Adjustable tip for a lancet device and method
Inventor: SCHRAGA STEVEN
IPC: A61B17/32
Filed: 2001-01-25
Abstract: A lancet device and a lancet device tip for a lancet device. The tip includes a first sleeve and a second sleeve at least partially contained within the first sleeve. The second sleeve includes a stop surface. Rotation of the first sleeve relative to the second sleeve causes the second sleeve to move at least axially without changing an overall length of the lancet device tip.
Patent EP-1303722-A4 (EP)
Title: High performance composite tubular structures
Inventor: LINDSAY HOWARD A
IPC: A63B53/10
Filed: 2001-06-14
Abstract: This invention relates generally to the design and manufacture of high performance, composite, tubular structures. More specifically, the invention relates to a high performance, composite, tubular structure that utilizes an integral pattern of ribs on the internal diameter ("ID") or outer diameter ("OD") surface of the tube. The present invention provides high performance, composite, tubular structures that are both lighter and stiffer than conventional tubes. In general, the present invention incorporates unconventional features into the design of tubular structures, to greatly enhance performance. For example, in accordance with one preferred embodiment of the present invention, tubular structures are enhanced by incorporating small, stabilizing, raised ribs on the ID of the tubes.
Patent EP-1297216-A4 (EP)
Inventor: LOGIN ROBERT B
IPC: D06M11/82
Filed: 2001-06-08
Abstract: La présente invention concerne, de manière générale, un procédé pour rendre des tissus contenant des fibres de coton plus plaisants d'un point de vue esthétique et plus résistants à la maculation par des colorants anioniques, cela par la dérivatisation du coton afin qu'il présente une charge anionique permanente. L'augmentation de la charge anionique des fibres permet d'accroître la résistance des fibres aux colorants anioniques, susceptibles de malencontreusement entrer en contact avec les fibres, ainsi que l'absorption d'adoucissants et de biocides cationiques par celles-ci. De plus, les charges négatives se repoussent mutuellement, avec pour résultat un tissu présentant une voluminosité et une hydrophilie plus grandes, et par conséquent plus de moelleux, un meilleur toucher, et un plus grand confort. La présente invention, outre son utilité pour empêcher la maculation mutuelle des tissus, peut également servir à rendre les tapis résistants à des agents maculants anioniques.
Patent EP-1313436-A4 (EP)
Title: Abrasive compositions and methods for making same
Inventor: MCGILL PATRICK D
IPC: A61K8/73
Filed: 2001-07-25
Abstract: Abrasive compositions comprised of water-insoluble abrasive polishing agents suspended in a liquid medium in combination with humectant, and methods for making same. The inventive abrasive compositions are rheologically stable, settling-resistant, and re-agglomeration resistant, even during and after transport and/or storage before end-use, such as incorporation into dentifrice formulations or other oral cleaning compositions. The high settling-resistance of the inventive abrasive composition makes it possible to avoid the need before end use for temporary stabilizers such as inorganic suspending agents (e.g., clays, fumed silicas) or organic binders (e.g., polysaccharides). Also, the abrasive compositions contain abrasive particles having improved brightness as compared to abrasive particles made via drying and dry comminution processing.
Patent EP-1308440-A4 (EP)
Title: Piperidine derivatives and drugs containing these derivatives as the active ingredient
Inventor: NAKAI HISAO
IPC: A61P25/24
Filed: 2001-08-09
Abstract: Piperidine derivatives represented by formula (I) or nontoxic salts thereof (wherein symbols are defined in the description): <CHEM>   Since the compound represented by formula (I) has a PDE4 inhibitory activity, it is useful for preventing and/or treating inflammatory diseases, diabetic diseases, allergic diseases, autoimmune diseases, osteoporosis, bone fracture, obesity, depression, Parkinson's disease, dementia, ischemia-reperfusion injury, leukemia and the like.
Patent EP-1307340-A4 (EP)
Inventor: HUNT ANDREW TYE
IPC: C23C16/40
Filed: 2001-07-13
Abstract: L'invention concerne des couches minces à joints de grain réduits (RGB) à utiliser en tant qu'électrolytes dans des piles à combustible à oxyde solide (SOFC), membranes de séparation de gaz, ou matériaux diélectriques de dispositifs électroniques, photoniques, radiofréquences et pyroélectriques. Au moyen de CCVD, CACVD ou de tout autre procédé de dépôt approprié, des couches RGB présentant une structure sans porosité, à joints de grain idéaux, et dense peuvent être formées. De plus, l'utilisation de couches minces RGB pour former des électrolytes et des électrodes dans des SOFC permet de densifier une microstructure interface/ à joints de grain idéaux et sans porosité. L'invention concerne également des membranes de séparation de gaz pour produire de l'oxygène et de l'hydrogène. Ces membranes semi-perméables sont formées de fines couches de haute qualité, denses, imperméables au gaz, d'oxydes à conducteurs mixtes sur des substrats en céramique poreux. L'invention concerne également des couches minces RGB en tant que matériaux diélectriques dans des condensateurs. Des condensateurs sont utilisés selon leurs valeurs de capacité qui dépendent de leur structure physique et de leur permittivité diélectrique. Selon l'invention, les couches minces RGB forment des couches diélectriques à faible perte et à permittivité extrêmement élevée. Cette permittivité élevée permet de former des dispositifs électronique, photonique etc  dont les propriétés peuvent être ajustées par application d'une polarisation CC entre leurs électrodes.
Patent EP-1336302-A4 (EP)
Title: Engine bearing inspection system
Inventor: CHANG TZYY-SHUH
IPC: G01N21/954
Filed: 2001-08-22
Abstract: An inspection system is used to view an image of the inside diameter (ID) of an engine bearing. The inspection system includes a stationary line scan camera, a pivoting mirror, a scanning mirror and a stationary mount. The engine bearing is placed in the stationary mount such that the bearing remains motionless throughout the entire scanning process. The light line generator produces a light line that initially contacts a beam splitter. The beam splitter then guides the light line onto the pivoting mirror, which then directs the light line onto one of a pair of stationary mirrors and then finally onto the scanning mirror. The scanning mirror will sweep the light line across a portion of the engine bearing ID surface. The light line will generate reflected images of the ID surface. These reflected images will return along the light line's path; however, instead of being directed back into the light line generator by the beam splitter, the reflected images will pass through the beam splitter. Once the reflected images pass through the beam splitter, they will journey through the lens and into the stationary line scan camera. From the stationary line camera, the reflected images can be viewed on a monitor and recorded for future use.
Patent EP-1348045-A4 (EP)
Title: Stable conjugated polymer electrochromic devices incorporating ionic liquids
Inventor: LU WEN
IPC: G02F1/15
Filed: 2002-01-03
Abstract: Electrochemical synthesis of conjugated polymers in ionic liquids, achievement of electroactivity and electrochroism of conjugated polymers in ionic liquids, and the use of the resulting conjugated polymers for the fabrication of electrochromic devices incorporating ionic liquids as electrolytes are described.
Patent EP-1352509-A4 (EP)
Title: Signal routing for reduced power consumption in a conferencing system
Inventor: HOWARD GUY
IPC: H04R1/26
Filed: 2002-01-16
Abstract: A technique is provided for reducing power consumption of an internally powered console in an audio system through frequency based signal routing. A system employing the technique includes a base unit having an interface for receiving a signal representative of acoustic information. The base unit includes a filter system for splitting the signal into low-frequency and high-frequency component signals. The low-frequency signal is routed to a first audio driver for reproduction. The high-frequency signal is routed to a device that includes a second audio driver. By removing the need to reproduce the low-frequency portion of the acoustic information, the power consumption of the device is reduced.
Patent EP-1411375-A4 (EP)
Title: Optical element having lanthanum fluoride film
Inventor: TAKI YUSUKE
IPC: C23C14/06
Filed: 2002-07-17
Abstract: An optical element comprising a fluorite substrate (1) and a lanthanum fluoride film (2) formed directly on the substrate (1). Since the plane of the substrate (1) with the lanthanum fluoride film (2) deposited thereon is a (1 1 1) plane, or inclined from the (1 1 1) plane by an angle of ± 30 ° or under, preferably, ± 15 ° or under, the lanthanum fluoride film is crystal-grown on the optical substrate with C-axis orientation. This lanthanum fluoride film is dense and has small surface area, few oxide and hydroxide areas and structural defects, and can reduce an optical loss of the optical element in a vacuum ultraviolet ray zone.
Patent EP-1422676-A4 (EP)
Title: Mobile communication apparatus, monitoring apparatus, monitoring system, monitoring method, monitoring program, and computer-readable recording medium containing the monitoring program
Inventor: OTSUKI YOSHIYUKI
IPC: B60R25/102
Filed: 2002-08-02
Abstract: A mobile communication device (3) can be disconnected form a vehicle monitoring apparatus (1) arranged on vehicle for sensing the state of the vehicle as a monitoring object and transmitting sensing data representing the sensing result. The mobile communication device (3) can also be connected via a communication network (4) to a report destination. The mobile communication device (3) includes a judgment unit (41a) for judging the state of the vehicle according to the sensing data, a decision unit (41b) for deciding a report destination to be connected according to the judgment result of the judgment unit (41a), and a communication unit (42) for receiving the sensing data and establishing a connection with the report destination decided by the decision unit (41b). Thus, it is possible to report the abnormal state of the vehicle sensed to an appropriate report destination in a short time. <IMAGE>
Patent EP-1380813-A4 (EP)
Title: Information providing method and information providing device
Inventor: KUDO TAKAHIRO
IPC: G01C21/34
Filed: 2002-08-05
Abstract: In a car navigation system (1), a position information detection means (11) detects position information on a vehicle using, for example, a GPS. A travel information history of the vehicle obtained based on the detected position information is accumulated in a travel information history means (15). When detecting an event such as start of an engine, an action prediction means (17) predicts a destination of the vehicle by referring to a route to the current time and to the accumulated travel information history. Commercial or traffic information regarding the predicted destination is acquired by an information acquisition means (18) from a server (2), and then is displayed on a screen, for example, by an information provision means (19). <IMAGE>
Patent EP-1389896-A4 (EP)
Title: Method for periodically elongating an electrode for an electric arc furnace
Inventor: KHLOPONIN VIKTOR NIKOLAEVICH
IPC: H05B7/14
Filed: 2002-03-28
Abstract: A method for periodic elongation of the electrode for the electric arc furnace and the electrode for the electric arc furnace. <??>The method includes screwing on the electrode column of an earlier prepared new electrode and a nipple with a longitudinal through hole with a metal rod in it, for example made of aluminium or copper, which is melted under the working temperatures of the electrode column with filling up cavities in the joint "electrodes-nipple", as well as with partial filling of the additional cavity in the body of the electrode, the gas mixture from the space of the additional cavity free of liquid metal being drawn to the working area of the furnace through provided holes in the body of the said electrode. <??>The electrode for the realization of the said method is made with additional cavities, placed along the central axis in the bottom of the threaded sockets, the said cavities having different diameters and depths and one of them being connected to the external surface of the electrode by means of holes. <IMAGE>
Patent EP-1374364-A4 (EP)
Inventor: BATSON DAVID C
IPC: H01M50/569
Filed: 2002-01-23
Abstract: La présente invention concerne un ensemble à bornes (14) permettant de mesurer le courant électrique passant par une borne de batterie. Il est constitué d'un rondelle électro-conductrice (28) servant à connecter une borne de batterie à une borne électro-conductrice (32) pouvant se connecter à une charge. Chaque ensemble (14) comporte une résistance de shunt (34) dont la valeur R est connue. le carter de batterie (18) comporte une carte circuit (52) équipé d'un voltmètre, d'une mémoire pour conserver la valeur R de résistance connue, et un processeur programmé pour effectuer des calculs sur la base des données et paramètres de batterie.
Patent EP-1429671-A4 (EP)
Title: Connection rod for screw or hook polyaxial system and method of use
Inventor: RITLAND STEPHEN
IPC: A61B17/88
Filed: 2002-09-30
Abstract: A low-profile surgical implant assembly is provided that includes a connector device that is an integral part of a rod, the connector device allowing the rod to be attached directly to a bone screw, such as a pedicle screw. Another aspect of the invention is a clamp device that allows the length of a rod spanning to attachment devices to be adjusted at the time of implantation, and further allows the clamp device to be secured by tightening a securing end of the clamp at the attachment device. The assemblies are useful for insertion into bone and connecting a foreign object to bone via a polyaxial coupling mechanism. A method for implanting the assembly is also provided.
Patent EP-1442358-A4 (EP)
Inventor: MENENDEZ ROBERT J
IPC: G08G1/13
Filed: 2002-10-24
Abstract: L'invention concerne un véhicule de service (12) destiné à effectuer des appels de service au niveau de plusieurs emplacements. Ce véhicule comprend un dispositif de détermination de position (14), un indicateur de sous-système (16, 18) indiquant une condition de sous-système de véhicule de service, et un dispositif de communication mobile associé (20). Un concentrateur (24) est en communication permanente avec un ordinateur central (31), et communique également avec le dispositif de détermination de position, l'indicateur de système, et le dispositif de communication mobile. L'invention concerne également un système (10) de surveillance d'un véhicule de service.
Patent EP-1516502-A4 (EP)
Title: A method for embedding a radio frequency antenna in a tire
Inventor: ADAMSON JOHN DAVID
IPC: B60C23/04
Filed: 2002-12-03
Abstract: A radio frequency antenna (12) for use with a radio device (10) embedded in a tire 14) for operation in a frequency range of at least 130 MHz, comprises an antenna body, and an insulating coating surrounding the antenna body, the insulating coating having a dielectric constant less than a dielectric constant of the rubber material, and preferably less than 3, and having a thickness of at least 0.02 mm. The coating material preferably has a surface resistivity of at least 10<12¿ ohms/sq and a volume resistivity of at least 10?9¿ ohms*cm. In addition, the coating material preferably has a dissipation factor less than 0.03. The antenna body is preferably a wire formed of spring steel, brass coated spring steel, or spring brass.
Patent EP-1483840-A4 (EP)
Title: Receiver for wireless telecommunication stations and method
Inventor: GRIECO DONALD M
IPC: H04B1/707
Filed: 2003-02-05
Abstract: The present invention is directed to an improved telecommunication receiver for receiving wireless multi-path communication signals. A novel RAKE receiver and a time diverse integration system (fig.1) for the calculation of the relative power of received signal samples are provided (Fat Finger Allocation and Rake Finger Allocation). Preferably, the receiver is embodied in a UE or base station of a CDMA wireless telecommunication system, such as a 3GPP system.
Patent EP-1555024-A4 (EP)
Title: Antibacterial medicinal composition of enhanced oral absorptivity
Inventor: YOKOI YUKIKO
IPC: A61K31/546
Filed: 2003-04-28
Abstract: An objective of the present invention is to provide a cefditoren pivoxil pharmaceutical preparation which can safely be administered to a patient and not only improves wettability of cefditoren pivoxil, but also further improves absorbability through the intestinal tracts by maintaining amorphous particles having a high oral absorbability in a liquid for a long period of time. The present invention is a pharmaceutical composition comprising amorphous cefditoren pivoxil and a sugar ester fatty acid, which is obtainable by mixing or wet-granulating particles containing amorphous cefditoren pivoxil with the sugar ester fatty acid while amorphous cefditoren pivoxil maintains its particle state. <IMAGE>
Patent EP-1551257-A4 (EP)
Inventor: SPROUSE II ANTHONY ERIC
IPC: A47C7/18
Filed: 2003-04-29
Abstract: L'invention concerne un coussin multicouches (10) présentant une base profilée (26) sur laquelle est disposée une couche de rembourrage (28) élastique. La base profilée (26) est constituée en mousse de support et présente une partie avant (44) et des traversins latéraux (51, 52). La couche de rembourrage est un coussin gonflable à alvéoles d'air comprenant une base flexible (57) et un réseau d'alvéoles d'air (58) individuelles disposées en rangées sur ladite base flexible. Les rangées d'alvéoles disposées autour du périmètre du coussin à alvéoles d'air sont configurées pour former des zones de transition confortables entre les traversins et le coussin à alvéoles d'air. Le coussin comprend une couverture (30) pourvue d'un compartiment inférieur (100) destiné à la base en mousse et un compartiment supérieur (98) destiné à la couche d'alvéoles d'air. Ladite couverture est utilisée pour maintenir la couche d'alvéoles d'air en place sur la couche de mousse.
Patent EP-1517945-A4 (EP)
Inventor: DE MAN AREN JOOST
IPC: C08K5/10
Filed: 2003-06-18
Abstract: L'invention concerne une pellicule calandrée d'halogénure de vinyle comprenant : (A) au moins un polymère d'halogénure de vinyle, (B) au moins un plastifiant polymère non halogéné et (C) au moins un second plastifiant différent du plastifiant polymère non halogéné. Une grande quantité des polymères de la pellicule contiennent le polymère d'halogénure de vinyle (A) et le film est allongé d'au moins environ 50 %. L'invention concerne également un article adhésif comprenant une couche autoadhésive pourvue d'une première surface et d'une seconde surface et une pellicule calandrée d'halogénure de vinyle collée à la première surface de la couche adhésive. Cette pellicule d'halogénure de vinyle comprend : (A) au moins un polymère d'halogénure de vinyle, (B) au moins un plastifiant polymère non halogéné et (C) au moins un second plastifiant, l'article adhésif étant allongé d'au moins environ 50 %.
Patent EP-1480037-A4 (EP)
Title: Measurement instrument
Inventor: MATSUMOTO DAISUKE
IPC: G01D11/24
Filed: 2003-02-28
Abstract: A measuring instrument (A) includes a pressurizing mechanism (C) which moves at least one of a measuring article (S) and a connector (4) toward and into pressing contact with the other when the measuring article (S) is placed at a measuring position (P). This prevents improper connection between the connector (4) and the measuring article (S) caused by wear of the connector (4). <IMAGE>