baber/WOPTO huggingface dataset:
Patent PT-1539753-E (PT)
Title: Pyrazolo(3,4-b)pyridine compounds, and their use as phosphodiesterase inhibitors
Inventor: HAMBLIN JULIE NICOLE
IPC: A61P11/00
Filed: 2003-09-12
Abstract: The invention relates to a compound of formula (I) or a salt thereof: wherein: R<SUP>1 </SUP>is C<SUB>1-4</SUB>alkyl, C<SUB>1-3</SUB>fluoroalkyl, -CH<SUB>2</SUB>CH<SUB>2</SUB>OH or -CH<SUB>2</SUB>CH<SUB>2</SUB>CO<SUB>2</SUB>C<SUB>1-2</SUB>alkyl; R<SUP>2 </SUP>is a hydrogen atom (H), methyl or C<SUB>1</SUB>fluoroalkyl; R<SUP>3 </SUP>is optionally substituted C<SUB>3-8</SUB>cycloalkyl or optionally substituted mono-unsaturated-C<SUB>5-7</SUB>cycloalkenyl or an optionally substituted heterocyclic group of sub-formula (aa), (bb) or (cc); in which n<SUP>1 </SUP>and n<SUP>2 </SUP>independently are 1 or 2; and in which Y is O, S, SO<SUB>2</SUB>, or NR<SUP>10</SUP>; or R<SUP>3 </SUP>is a bicyclic group (dd) or (ee): and wherein X is NR<SUP>4</SUP>R<SUP>5 </SUP>or OR<SUP>5a</SUP>. The compounds are phosphodiesterase (PDE) inhibitors, in particular PDE 4 inhibitors. Also provided is the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment and/or prophylaxis of an inflammatory and/or allergic disease in a mammal such as a human, for example chronic obstructive pulmonary disease (COPD), asthma, or allergic rhinitis.
Patent PT-1562953-E (PT)
Title: Process for the preparation of quaternary n-alkyl morphinan alkaloid salts
Inventor: CANTRELL GARY L
IPC: C07D489/02
Filed: 2003-11-05
Abstract: A process for the preparation of a quaternary derivative of the morphinan alkaloid, the process comprising contacting a tertiary N-substituted morphinan alkaloid with an alkyl halide in an anhydrous solvent system, wherein the solvent system comprises an aprotic dipolar solvent with the aprotic dipolar solvent constituting at least 25 wt % of the solvent system.
Patent PT-1581376-E (PT)
Title: Method and apparatus for plastic deformation of polymers
Inventor: SCHROETER JOHANNES
IPC: B29B13/00
Filed: 2003-12-11
Abstract: According to the invention, a method for the plastic deformation of a polymer is provided, which is characterized in that the polymer is treated with electromagnetic radiation having a wavelength in the range from 0.8 to 100 μm with simultaneous action of pressure and shearing and thermal energy. By means of the method according to the invention, it is also possible to plastically deform polymers which have to date not been accessible to plastic deformation, such as chitin and in particular cellulose.
Patent PT-1489427-E (PT)
Title: Selective measurement of a directional component of the flow velocity using a cup anemometer
Inventor: WESTERMANN DIETER
IPC: G01P5/02
Filed: 2004-06-12
Abstract: Method for measuring a flow velocity, especially of the wind, using a vane anemometer in which the smaller aerodynamic resistance coefficient for the convex side of the anemometer vanes is increased for flows incident on the vane at a tilt angle of less than minus 15[deg] or greater than plus 15[deg].
Patent PT-1773708-E (PT)
Title: Apparatus for pharmaceutical production
Inventor: CLARKE ALLAN J
IPC: B67B7/00
Filed: 2005-06-09
Abstract: A method for producing a pharmaceutical product (3000) is provided in which a dose (2000) of active material in liquid form is dispensed onto a solid carrier substrate (1000) during continuous movement of the substrate (1000) on a conveyor (310), followed by drying. The method facilitates real-time monitoring of the amount of active material deposited onto the carrier substrate (1000) during the method.
Patent PT-1816117-E (PT)
Title: Method for manufacturing nitrobenzole
Inventor: THOMAS KNAUF DR
IPC: C07C201/16
Filed: 2007-01-19
Abstract: Preparation of nitrobenzene comprises reacting benzene with nitric acid to give nitrobenzene, washing the raw nitrobenzene in an acid, alkaline or neutral wash with water, and removing the raw nitrobenzene from water and benzene. Preparation of nitrobenzene comprises reacting benzene with nitric acid to give nitrobenzene, washing the raw nitrobenzene in an acid, alkaline or neutral wash with water, and removing the raw nitrobenzene from water and benzene, where the step of washing the nitrobenzene in neutral wash with water comprises mixing the raw nitrobenzene with water in a mixing medium and dispersing such that the organic phase essentially containing nitrobenzene is at least partially dispersed, supplying the dispersion to an electrophoresis-unit, in which the dispersion is applied by breaking an electric DC voltage and subsequently separating the aqueous and the organic phase.
Patent PT-2068692-E (PT)
Title: Wringer
Inventor: DINGERT UWE
IPC: A47L13/58
Filed: 2007-09-14
Abstract: The mop wringing system comprises a basket-shaped wringer (3) mounted on top of a bucket. The head of the mop (2) is pushed into this to wring it out. The basket is made up of inner (5) and outer (6) strips connected at the top and with spacers at the base which are connected to them by film hinges.
Patent PT-2190594-E (PT)
Title: Method of processing postal packages with client codes associated with digital imprints
Inventor: MIETTE EMMANUEL
IPC: G06V10/50
Filed: 2008-08-12
Abstract: In a method of processing mailpieces, Customer Applied Identifier (CAI) codes are assigned to the mailpieces by a sender of the mailpieces, and are used by the postal operator while the mailpieces are passing through a postal sorting system. Said CAI codes are recorded in memory in the sorting system in correspondence with first digital fingerprints or image signatures prior to the first pass of the mailpieces through the postal sorting system. While a current mailpiece is passing through the sorting system in a first sorting pass, an image is formed of the surface of the mailpiece that bears a postal address block, and a current fingerprint and location information for locating said mailpiece in the sorting process is derived from the image of said mailpiece. A search is made for a match between said current fingerprint and a first fingerprint recorded in memory in order to retrieve a current CAI code with which said location information is.
Patent PT-2226085-E (PT)
Title: Anti-angiogenic compositions and methods of use
Inventor: HUNTER WILLIAM L
IPC: A61K47/42
Filed: 1994-07-19
Abstract: The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and taxol. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
Patent PT-783285-E (PT)
Inventor: LI SHU-TUNG
IPC: A61F2/82
Filed: 1994-09-14
Abstract: The present invention is related to prostheses, their methods of manufacture and methods for repairing vascular lesions using such prostheses. Natural polymers such as collagen are processed and fabricated to form tubular resorbable vascular wound dressings with unique physico-chemical and mechanical properties for repairing selected vascular segments, and for delivering therapeutic agents at selected sites within vessels and at the anastomoses.
Patent PT-758560-E (PT)
Inventor: WANG QUN
IPC: C12H1/044
Filed: 1995-09-21
Abstract: Highly purified non-calcined, calcined, and flux-calcined diatomite products are disclosed, as are methods for their preparation, which bear the distinguishing porous and intricate structure of silica unique to diatomite and which have an extraordinarily high silica (i.e., silicon dioxide, SiO2) content and low density, resulting in high silica specific volume. These products often also exhibit exceptionally low soluble metals content and/or extreme brightness and can be used in filtration processes, eg. in filtering beer. <IMAGE>
Patent PT-742796-E (PT)
Inventor: ABRAMS MARK ALLEN
IPC: C12N15/24
Filed: 1995-01-25
Abstract: The present invention relates to fusion molecules composed of human interleukin-3 (hIL-3) variant or mutant proteins (muteins) functionally joined to a second colony stimulating factor (CSF), cytokine, lymphokine, interleukin or IL-3 variant. These hIL-3 variants contain amino acid substitutions and may also have amino acid deletions at both the N-and C- termini. The invention also relates to pharmaceutical compositions containing the fusion molecules and methods for using them.
Patent PT-723475-E (PT)
Inventor: EKHOLM ROLF
IPC: D21C9/10
Filed: 1994-10-04
Abstract: Process and device for mixing fluid into a pulp suspension of cellulose-containing fiber material, in which the pulp suspension is pumped in through a pump inlet (17), brought into rotation and, at the desired reaction pressure, mixed with the said fluid while passing through a reaction sector comprising a stator shell (1), a rotor (7) which is coaxial therewith, and at least one fluid inlet (23), after which the pulp mixture leaves the reaction sector through a pulp outlet (20), in which the fluid, via the said fluid inlet (23), is supplied in the vicinity of the center of rotation of the rotating pulp suspension, where the local pressure in the pulp suspension is lower, due to the centrifugal force increasing radially outwards, than the reaction pressure prevailing at the periphery of the pulp suspension.
Patent PT-760366-E (PT)
Inventor: NISHIURA AKIO
IPC: A61K31/557
Filed: 1996-08-23
Abstract: Prostaglandin E1 ester derivatives of the formula (I): <CHEM> wherein the groups R<1> are the same as each other and are C4-12 alkyl; or cyclodextrin clathrates thereof, liposome formulations containing them, processes for their preparation and pharmaceutical compositions containing them, as active ingredient. The compounds of formula (I) have the effect of increasing blood flow and are useful for the prevention and/or treatment of peripheral circulatory disorder, decubitus, or skin ulcers, or for the maintenance of blood flow.
Patent PT-923381-E (PT)
Inventor: BAN IVAN
IPC: A61K35/22
Filed: 1996-08-30
Abstract: Disclosed is a method to obtain an extract containing a natural mixture of conjugated oestrogens from mare's urine by solid-phase extraction of the mixture of conjugated oestrogens from pregnant mare's urine on non-ionic semipolar polymer adsorbing resins.
Patent PT-1003920-E (PT)
Inventor: RATZ GERHARD
IPC: C22C38/22
Filed: 1998-08-06
Abstract: The invention relates to a high-strength steel track element, and process of making the steel track element by rolling and heat treating. The steel comprises: 0.3-0.6% C, 0.8-1.5% Si, 0.7-1.0% Mn, 0.9-1.4% Cr, 0.6-1.0% Mo, balance iron and smelting-related impurities. The steel has a bainitic basic structure, a tensile strength of at least 1600 N/mm2 and a technical yield strength of at least 1250 N/mm2.
Patent PT-1083816-E (PT)
Inventor: GRANGER MAURICE
IPC: A47K10/36
Filed: 1999-04-12
Abstract: A device for inserting a strip of material in a dispensing machine for material wipes of the type in which the machine includes a housing, a cover, the housing having end shields that support a reel holder, and a drum with a cutting device. The drum includes a cam associated with a start and return spring, a protection flap being located in front of the drum along with a pressure roller resting against the drum. The protection flap has an upper extension forming a support frame devised to accommodate a hinged secondary flap and a swivelling shaped plate is located behind the drum and capable of supporting a service roll that is being used up. The swivelling shaped plate cooperates with a mechanism capable of locking the secondary flap in position when a spare roll (RR) is being loaded and the service roll (RS) is positioned so that it can be used up.
Patent SG-24495-G (SG)
Title: Washing device for parts of human body
Inventor: TSUTSUI OSAMU
IPC: G05D23/13
Filed: 1995-02-16
Abstract: A washing device for parts of human body comprises a thermostat mixing valve (T) which is disposed at a junction of a cold-water supply passage (2) and a heated-water supply passage (1), a latching solenoid valve (V1) which is mounted on a heated-water drainage passage (6) branched out from said heated-water supply passage (1) and a latching solenoid valve (V2) which is mounted on a mixed-hot-water supply passage (m). Due to such construction, electric power for heating water is no more necessary in the toilet bowl (B) and electric power for mixing heated water and cold water to produce mixed hot water to be ejected from an ejecting nozzle (7) also becomes unnecessary. Furthermore, electric power for operating the solenoid valve (V1, V2) is minimized by means of a latching solenoid. Accordingly, the overall consumption of electric power necessary for operating and controlling the washing device can be minimized thus enabling the use of a small dry (D) cell or battery as an electric power source of the washing device.
Patent SG-112187-G (SG)
Title: Guanidine derivatives and pharmaceutical compositions containing them
IPC: C07D211/56
Filed: 1987-12-30
Abstract: This invention relates to novel guanidine derivatives of the general formula 
<CHEM>
 their isomers at the guanidine group and salts of such compounds. The compounds and their salts are useful as anthelmintics.
Patent IE-820050-L (IE)
Title: Grouping unitary dose containers
IPC: B65B17/02
Filed: 1982-01-12
Abstract: An apparatus for grouping unitary dose containers which have polygonal collars receives such containers from a supply magazine and directs them by a first transfer device onto mandrels on plates carried by a rotating drum. The containers are carried by the drum to a second station where heads of a joining device join adjacent edges of collars of selected containers. Subsequently, the drum is further rotated for carrying the joined containers to another station where a second transfer device transfers the joined containers onto a receiving device.
Patent IE-37172-L (IE)
Title: Selective signalling apparatus for telephone instrument.
IPC: H04M1/515
Filed: 1973-01-31
Abstract: 1370221 Impulse transmitters STANDARD TELEPHONES & CABLES Ltd 16 March 1972 12354/72 Heading H4K [Also in Division G4] In a selective signalling apparatus, e.g. a push button operated telephone, a set of contacts forming at least some of the contacts operated by pushbuttons to provide a coded condition are connected such that when operated a strobe signal is activated to connect the coded condition to a signal generator. In the instrument shown sixteen buttons are provided with common column contacts X1-X4 and common row contacts Y1-Y4 so that operation of each pushbutton is uniquely signalled to a coding circuit by closure of a respective pair of contacts. A strobe signal is provided for transmitting on the output of the coding circuit and this strobe signal is generated when any one of contacts X1-X4 are operated. Since one of these contacts will always need to be operated a separate common strobe signal contact can be dispensed with. Preferably the contacts X1- X4 close after the contacts Y1-Y4. In a modification each pushbutton controls its own pair of contacts one of which is connected additionally to the strobe signal supply, Fig. 3 (not shown). Diodes are used to ensure that spurious operation does not occur.
[GB1370221A]
Patent IE-860429-L (IE)
Title: Dry food product
IPC: A23L19/00
Filed: 1986-02-17
Abstract: A dry food product reconstitutable with cold or hot aqueous liquid to a pulpily structured fruit sauce, soup, juice, compote, concassée, savoury vegetable-containing soup or snack meal containing added starch and, optionally, further consistency - and/or structure-imparting components as well as at least one taste-and/or flavor imparting dry vegetable and/or fruit component (fruit substance), is characterized in that the added starch consists at least partially of cold-swelling leguminous pre-gelatinized starch.
Patent IE-44711-L (IE)
Title: 17ó-hydroxypropyl-delta 4-3-keto-steroids and esters and¹ethers thereof
IPC: C07J53/00
Filed: 1977-03-02
Abstract: 4-Androsten-3-ones of the formula <IMAGE> wherein R1 is hydrogen or the acyl radical of an organic or inorganic acid, R2 is hydrogen, alkyl, or the acyl radical of an organic or inorganic acid, R3 is methyl or ethyl, R4 is hydrogen or methyl, <IMAGE> <IMAGE> +tr <IMAGE> and R5 is lower alkyl, have diuretic activity.
[US4118488A]
Patent IE-900701-L (IE)
Title: Microcapsules containing hydrophobic liquid core
IPC: B01J13/02
Filed: 1990-02-27
Abstract: Microcapsules which are prepared using coacervation processes and/or which have a complex structures in which there is a large central core of encapsulated material, preferably perfume, and the walls contain small wall inclusion particles of either the core material or some other material that can be activated to disrupt the wall are disclosed. The microcapsules that are prepared by coacervation and contain perfume are especially desirable for inclusion in fabric softener compositions that have a pH of about 7 or less and which contain cationic fabric softener. The encapsulated perfume preferably does not contain large amounts of relatively water-soluble ingredients. Such ingredients are added separately to the fabric softener compositions. Ingredients that have high and low volatilities as compared to, e.g., the desired perfume, can either be added to, or removed from, the perfume to achieve the desired volatility.
Patent IE-36390-L (IE)
Title: Aqueous solutions of oxytetracycline
IPC: A61K9/00
Filed: 1972-05-25
Abstract: 1361491 Oxytetracycline solutions PFIZER Ltd 4 Sept 1972 [5 June 1971] 19132/71 Heading A5B A process for the preparation of aqueous solutions of oxytetracycline comprises mixing together in an aqueous medium oxytetracycline, either as a free base or as a salt, a magnesium compound ionizable in the medium to provide magnesium ions, and polyvinyl pyrrolidone, the pH of the mixture being adjusted to a value in the range from 8.0 to 9.5 by adjusting the pH of one or more of these three components of the mixture in an aqueous medium prior to mixing with the remaining component or components, and no pH adjust ment being made subsequent to mixing of these three components. Stabilisers such as a metabisulphite or formaldehyde sulphoxylate salt may also be present.
[GB1361491A]
Patent IE-830777-L (IE)
Title: Compositions of imazolil and hexamidine isethionate for acne
IPC: A61Q19/00
Filed: 1983-04-06
Abstract: A pharmaceutical preparation for the topical treatment of acne is disclosed comprising a combination of Imazilil and Hexamidine as essential active substances. This combination shows antimicrobial activity higher than that of the individual substances.
Patent IE-830822-L (IE)
Title: IMIDAZO £1,2-c| PYRAZOLO £3,4-e| PYRIMIDINES
IPC: C07D487/14
Filed: 1983-04-11
Abstract: Alkylimidazo[1,2-c]pyrazolo[3,4-e]pyrimidines and pharmaceutically acceptable salts are described. These compounds are antipsychotic agents. Methods for their preparation, pharmaceutical compositions which contain them and methods for using said compositions are also described.
[US4469868A]
Patent FI-810993-L (FI)
Inventor: CHILD ROBERT PAUL
IPC: B01F3/04
Filed: 1981-03-31
Abstract: An appliance for making an aerated beverage including a casing (10) a connection (13,14) carried by the casing for mounting a container (12) of pressurized liquid carbon dioxide, a transparent shatterproof housing (52) for a bottle of water carried by said casing, a nozzle (18) communicating with the connection and extending from the support member downwardly within the housing, a stopper for engaging in the neck of a bottle and a table base (64) for supporting the bottle (80) in the housing so that the stopper is engaged in its neck. A manually operable valve (32) allows carbon dioxide to flow from the container (12) to the nozzle and a safety pressure valve (42) is connected to the interior of the bottle when the stopper is engaged in its neck. A bulb (82) illuminates the bottle at least while the water therein is being aerated, the illumination being picked up by the bubbles of carbon dioxide and giving a pleasing visual effect.
Patent FI-813994-L (FI)
Inventor: SCHAD ALFRED
IPC: F24D3/00
Filed: 1981-12-11
Abstract: A plastic pipe comprising an oxygen-impermeable casing, wherein the casing comprises a barrier layer for oxygen, and an adhesive layer adjacent to the circumferential surface of the pipe and attached to the circumferential surface by an sealed bond, wherein the casing surrounds the circumferential surface on all sides, and wherein the barrier layer is elastic, is substantially impermeable to oxygen and comprises a polyvinyl alcohol, a vinyl alcohol/ethylene copolymer, or polyacrylonitrile. Also disclosed is a process for the production of the pipe and a use of the pipe as a heating pipe.
Patent FI-843830-L (FI)
Inventor: SCHEPERS HERMAN AUGUSTINUS JOH
IPC: C08L7/00
Filed: 1984-09-28
Abstract: The invention concerns a thermoplastic moulding compound based on a rubber-modified copolymer consisting of styrene and/or  alpha -methylstyrene and maleic anhydride, characterized in that the moulding compound consists of a mixture of
 A. 50-95 % (wt) of a copolymer consisting of:
 1. 50-95 % (wt) styrene and/or  alpha -methylstyrene
 2. 50-5 % (wt) maleic anhydride
 3. 0-20 % (wt) acrylate
 4. 0-20 % (wt) acrylonitrile
 B. 5-50 % (wt) of an ethylene-propylene rubber or ethylene-propylene-diene rubber modified by grafting with a compound containing hydroxyl, amide or amine.
 C. 0-30 % (wt) ethylene-propylene rubber or ethylene-propylene-diene rubber.
 The compounds have in addition to a good UV resistance an excellent impact resistance and dimensional stability under heat and rigidity.
Patent FI-851952-L (FI)
Inventor: GENNARI FEDERICO
IPC: C07H19/16
Filed: 1985-05-16
Abstract: The present invention relates to new stable sulpho-adenosyl-L-methionine (SAMe) salts particularly suitable for parenteral use, their production process, and pharmaceutical compositions containing them as active principles. Said salts correspond to the general formula: SAMe.n(CH2)m(SO3H)2(I) where n can vary from 1 to 2 and m can vary from 3 to 12. The process for producing said salts consists of the following stages: (a) enriching the starting yeast with SAMe; (b) lysing the cells and recovering a solution rich is SAMe (cell lysate); (c) prepurifying the cell lysate by ultrafiltration; (d) passing the prepurified lysate through a column of weak acid ion exchange resin and eluting with the required disulphonic acid; (e) passing the eluate of said column through a column of absorption resin and washing with the required disulphonic acid; (f) concentrating the eluate of the latter column by reverse osmosis; (g) drying the concentrated solution.
Patent IE-781155-L (IE)
Title: Thienotetrahydropyridines
IPC: C07D495/04
Filed: 1978-06-07
Abstract: This invention relates to a process for the preparation of compounds having the general formula:  (I) in which: R1 represents a hydrogen atom, an optionaly substituted alkyl, aryl or aralkyl radical; R2 and R3 are the same or different and represent independently a hydrogen atom, a lower alkyl, aryl or heterocyclic radical; and R4 represents a hydrogen atom or an alkyl, cycloalkyl, alkoxy carbonyl, carboxy, aryl or heterocyclic radical, comprising reacting a compound having the formula:  (II) in which R1, R2 and R3 are as defined above, with a compound having the formula:  (III) in which R4 is as defined above; X is a halogen atom, or an optionally substituted alkoxy, thioalkyl or amino group; and Y represents an optionally substituted alkoxy, thioalkyl or amino group, or a group of the formula:  in which R is a lower alkyl or aryl radical; or both the groups X and Y, together with the carbon atom to which they are attached, form a 6-membered hexahydro-S-triazinic, trioxannic or trithianic heterocyclic nucleus, in an inert solvent, at a temperature between 0 DEG and 150 DEG C. and in an anhydrous medium, and, if desired, liberating the free base. (From US4174448 A) [FR2397417A1]