baber/WOPTO huggingface dataset:
Patent NZ-582826-A (NZ)
Title: Transdermal composition comprising (2S)-(4E)-N-methyl-5-(5-isopropoxy-pyridin-3-yl)-4-penten-2-amine
Inventor: WILLIAMS MICHAEL G
IPC: A61K31/465
Filed: 2008-07-30
Abstract: Disclosed is a transdermal composition which comprises: (1) an impermeable backing; (2) a reservoir layer comprising (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridinyl)-4-penten-2-amine (or (2S)-(4E)-N-methyl-5-(5-isopropoxy-pyridin-3-yl)-4-penten-2-amine) or a pharmaceutically acceptable salt thereof (such as the hydroxybenzoate salt) in a phosphate buffered saline solution, at a concentration of from 30 to 200 mg per gram of saline solution; (3) a membrane layer, which is a dense polymer membrane or a microporous membrane; (4) a contact adhesive layer which either covers the entire device surface in a continuous or discontinuous coating or surrounds the membrane layer; and (5) a penetration enhancer. Further disclosed is the use of the composition as defined above for the manufacture of a medicament for the treatment or prevention of a central nervous system disorder associated with an alteration in normal neurotransmitter release.
Patent NZ-586425-A (NZ)
Title: Electrostatic painting robot with paint cartridge and feeding mechanisim
Inventor: MITSUI MICHIO
IPC: B05B5/04
Filed: 2008-11-04
Abstract: Disclosed is a coating robot including an electrostatic paint applicator (2) attached to a robotic arm (1) and configured to supply the electrostatic paint applicator (2) with paint from a paint bag (6) accommodated in a paint cartridge (4) detachably attached to a rear end of the electrostatic paint applicator (2) by squeezing the paint bag (6) in the paint cartridge (4) with a controlled amount of actuating liquid supplied into the paint cartridge (4). The robot includes a tank (25) fixed on the robotic arm (1) and containing the actuating liquid and an actuating liquid supply path for supplying the actuating liquid from the tank (25) to the paint cartridge (4). The coating robot further includes a pump (24) interposed in the actuating liquid supply path to supply the actuating liquid from the tank to the paint cartridge (4) under pressure, and a connection means (26) provided in an actuating liquid refill station and configured for relative movement to and away from the actuating liquid supply path. When the connection means (26) approaches and gets into connection with the actuating liquid supply path, the tank (25) is refilled with the actuating liquid supplied from an actuating liquid source (34) through the liquid supply path.
Patent NZ-587361-A (NZ)
Title: Diazepanyl derivatives for the treatment of the skin conditions acne, seborrhea and seborrheic dermatitis
Inventor: BLASKOVICH MARK ARNOLD THOMAS
IPC: A61K31/551
Filed: 2009-02-27
Abstract: Disclosed is the use of compounds of formula (I) and salts thereof for the treatment of acne, seborrhoea (seborrhea) and seborrheic dermatitis. Compounds of formula (I) down-regulate the activity of the melanocortin-5 receptor (MC5R). Specific examples of compounds of formula (I) include: N-(((3S,5S)-1-(3,5-dichlorobenzyl)-3-(3-guanidinopropyl)-2-oxo-1,4-diazepan-5-yl)methyl)-2-naphthamide, N-(((3S,5S)-1-(2,2-diphenylethyl)-3-(3-(isopropylamino)propyl)-2-oxo-1,4-diazepan-5-yl)methyl)-2-naphthamide, N-(((3S,5S)-1-(2,2-diphenylethyl)-3-(3-guanidinopropyl)-2-oxo-1,4-diazepan-5-yl)methyl)isoquinoline-3-carboxamide, N-(((3S,5S)-1-(2,2-diphenylethyl)-3-(3-guanidinopropyl)-2-oxo-1,4-diazepan-5-yl)methyl)benzofuran-2-carboxamide, and 3,4-dichloro-N-(((3S,5S)-3-(2-(4,4-difluoropiperidin-1-yl)ethyl)-2-oxo-1-((S)-2-phenylbutyl)-1,4-diazepan-5-yl)methyl)benzamide;
Patent NZ-588585-A (NZ)
Title: A conjugate comprising a targeting peptide selected from NGR, isoDGR or RGD combined with a cytokine selected from TNFalpha and TNFbeta for the treatment of mesothelioma
Inventor: BORDIGNON CLAUDIO
IPC: A61K47/48
Filed: 2009-05-12
Abstract: Disclosed are conjugates of cytokines and targeting peptides that is able to bind to a receptor expressed on tumor-associated vessels or to a component of the extracellular matrix associated to the tumor vessels, for treatment of malignant pleural mesothelioma. In particular, the invention provides conjugates comprising the cytokine TNF linked to a peptide containing the NGR motif. The invention further provides pharmaceutical compositions comprising such conjugate and pharmaceutical formulations comprising conjugates dissolved in appropriate buffers.
Patent NZ-588658-A (NZ)
Title: Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor
Inventor: PARR RYAN
IPC: C07H21/00
Filed: 2009-03-27
Abstract: Disclosed is an isolated mitochondrial fusion transcript associated with cancer, wherein the transcript comprises a nucleic acid sequence as set forth in SEQ ID NO: 18 or SEQ ID NO: 33.
Patent NZ-589429-A (NZ)
Title: Apparatus for measuring methane and carbon dioxide levels in a ruminant's breath and providing supplements accordingly
Inventor: LEMBKE KENT A
IPC: A61B5/097
Filed: 2009-05-22
Abstract: Disclosed is an apparatus (110) for monitoring methane emissions from a ruminant (204). The apparatus (120) is comprised of means for receiving the ruminant's head, a methane monitoring device (116) and a container. The methane monitoring device (116) is positioned proximate to the means for receiving the ruminant's head and is arranged to monitor methane (214) in exhaled breath of the ruminant (204). The container dispenses a supplement for consumption by the ruminant (204) in response to a determined level of methane (214) in the exhaled breath.
Patent NZ-592301-A (NZ)
Title: Method and apparatus for using compressed air to increase the efficiency of a fuel driven turbine generator
Inventor: ENIS BEN M
IPC: F02C7/05
Filed: 2009-10-06
Abstract: A method and apparatus is shown for increasing the efficiency of a fuel driven turbine generator, and in particular, a system comprising a turbo compressor and turbo expander device that produces super chilled air that can be mixed with ambient air to produce relatively cool dry inlet air that can be introduced under pressure into the fuel driven generator to increase the efficiency thereof. A separation compartment with a passageway extending normal to the travel direction of the chilled air is preferably used to remove ice particles and particulates from the cool inlet air to avoid damage to the turbine blades. Additional efficiency increasing apparatuses such as heat exchangers and steam driven turbine generators and chillers that use heat from the compressors, as well as thermal energy storage systems that store chilled water produced by releasing compressed air are contemplated.
Patent NZ-593831-A (NZ)
Title: Compositions and methods for the treatment or prevention of staphylococcus aureus infections and for the eradication or reduction of staphylococcus aureus on surfaces
Inventor: HEIL MATTHEW
IPC: C12N11/18
Filed: 2010-01-06
Abstract: Patent No. 593831 Disclosed is the use of a composition comprising digestive enzymes comprising protease, amylase, and lipase, in the manufacture of a medicament for the treatment or prevention of S.aureus infection in a bird or mammal, wherein treatment comprises oral administration, topical administration, transmucosal administration, or application to a wound, of the medicament to a bird or mammal in need thereof.
Patent NZ-594100-A (NZ)
Title: A coal based water resiatant solid carbonaceous fuel of density 500-750 Kg/m^3
Inventor: AUELL PATRICK B
IPC: C10L5/08
Filed: 2008-08-01
Abstract: A method of forming a ribbon or flaked lignite of high density and low water content comprising: comminuting a lignite feedstock to form a crushed lignite; compacting the crushed lignite in roll press comprising first and second counterrotating rolls, each roll comprising a circumferential profile of assemblages of ridge and valley arcs connected by straight tangent segments repeating at equal spacing around the circumference of the roll; the first and second counter-rotating rolls rotated in timed counter-rotation to match together peaks and valleys of the first and second counter-rotating rolls, respectively, and compact the crushed lignite between respective peaks and valleys of the first and second counter-rotating rolls; and, drying the compacted material with air warmed to a temperature above ambient temperature to produce a ribbon or flaked lignite material. 2. The method of Claim 1, wherein the ribbon or flaked lignite produced in the drying step has a moisture level of less than about 20%, and a bulk density greater than about 600 Kg/m3   3. The method of either Claim 1 or Claim 2, wherein the ribbon or flaked lignite produced in the drying step is shaped by further compaction processes into briquettes. 4. The method of either Claim 1 or Claim 2, wherein the ribbon or flaked lignite produced in the drying step is mixed into a liquid to form a slurry. 5. The method of Claim 4, wherein the liquid is water.
Patent NZ-595588-A (NZ)
Title: Computer implemented auction
Inventor: WAKIM BUDDY
IPC: G06Q30/08
Filed: 2010-03-12
Abstract: 595588 Disclosed is a server processing system (200) for conducting a real time auction. The server processing system (200) receives, from a seller terminal system (220, 221, 222), request data indicative of a seller’s request to auction an asset. A real-time auction is opened via an auction portal (210) hosted by the server processing system (200) for auctioning the asset. The server processing system (200) is able to receive and distribute auction activity data in real-time to and from one or more bidder terminal systems (230, 231, 232). Using the auction activity data, a determination is made if the auction of the asset has satisfied a close condition of the real-time auction. The real time auction of the asset is then closed in response to the close condition being satisfied. The server processing system (200) is further configured to receive, prior to opening the real time auction for the asset, a proxy bid request from a bidder (235, 236, 237) and determine, based upon historical sales data, a highest bid value. One or more bids are submitted on behalf of the respective bidder associated with the proxy bid request during the real time auction of the asset if the one or more bids fail to exceed the highest bid value.
Patent NZ-598208-A (NZ)
Title: Inhibitors of flaviviridae viruses
Inventor: CHO AESOP
IPC: C07F9/32
Filed: 2010-09-07
Abstract: ABSTRACT - 598208 The disclosure relates to a compound of Formula (I) e.g. 5-(3,3-Dimethyl-but-1-ynyl)-3-[[trans-4-(dimethyl-dimethylphosphinoyloxy)-cyclohexyl]-(trans-4-methyl-cyclohexanecarbonyl)-amino]-thiophene-2-carboxylic acid or a pharmaceutically acceptable salt or ester thereof wherein the variables are as defined in the specification. These compounds are suitable for treating a Flaviviridae viral infection, particularly the viral infection that is caused by a Hepatitis C virus.
Patent NZ-599178-A (NZ)
Title: Drainage body
Inventor: MEINCKE ARNE
IPC: E02B11/00
Filed: 2010-10-05
Abstract: 599178 A drainage body which has two substantially identically formed surface-area units, namely a base unit (11) and a substantially identically formed cover unit (12), which can be connected to one another in an installed state via spacer elements. The surface-area units can be stacked in a substantially inter-engaging manner such that the spacing between the surface-area units in the installed state is substantially greater than the spacing therebetween in the stacked state. Side walls (15) are provided such that they are attachable to the base units and to the top units to combine with each other. The spacer elements may be substantially in the form of a truncated cone or truncated pyramid with a circumscribed cross-sectional surface area which decreases as the spacing from the surface-area units increases. As an alternative to this, provision may be made for the spacer elements to be arranged on the surface-area units such that the base units and the cover units can be laid to overlap one another in the manner of a masonrywork assembly. This gives rise to a high level of stability with, at the same time, space-saving storage capability and transportation capability.
Patent NZ-601339-A (NZ)
Title: Production of soluble soy protein products
Inventor: SCHWEIZER MARTIN
IPC: A23L11/00
Filed: 2010-01-25
Abstract: Patent No. 601339 Disclosed is a process of preparing a soy protein product having a protein content of at least 60 wt% (N x 6.25) dry weight, which comprises: extracting a soy protein source to solubilize soy protein in the source material and to form an aqueous soy protein solution having a pH of 5 to 7, concentrating the aqueous soy protein solution to a concentration of 50 to 400 g/L to form a concentrated soy protein solution, optionally diafiltering the concentrated soy protein solution to form a concentrated and diafiltered soy protein solution, acidifying the concentrated and optionally diafiltrated soy protein solution to a pH of 2.0 to 4.0, and drying the acidified soy protein solution to provide the soy protein product, or diluting the concentrated soy protein solution into chilled water having a temperature of less than 15°C to cause formation of soy protein micelles, permitting the soy protein micelles to coalesce into a soy protein micellar mass, separating the soy protein micellar mass from the supernatant, acidifying the protein solution isolate to a pH of 2.0 to 4.0, and drying the separated soy protein micellar mass to provide a soy protein product.
Patent NZ-603300-A (NZ)
Title: Hose pull apparatus and method
Inventor: KORUS THOMAS J
IPC: A01G25/09
Filed: 2011-09-30
Abstract: A hose-fed lateral move irrigation system and method that utilizes a pipe with a plurality of sprinklers attached to a wheeled cart (22) that pulls a flexible-hose assembly therebehind using at least one onboard winch (150) and travels laterally with the pipe and sprinklers relative to a field so that a sufficient amount of hose may be used to enable total automation of the system. The flexible-hose assembly includes at least a flexible hose (126, 132, 136) and a rigid hose (130, 134) having a first portion and a second portion connected to the movable cart in that order.
Patent NZ-603799-A (NZ)
Title: The use of sgc stimulators, sgc activators, alone and combinations with pde5 inhibitors for the treatment of systemic sclerosis (ssc).
Inventor: FOLLMANN MARKUS
IPC: C07D471/04
Filed: 2011-05-24
Abstract: Disclosed herein is the use of sGC stimulators and sGC activators of formulae 1-27 for the manufacture of medicaments for the prevention and treatment systemic sclerosis, diffuse Systemic Sclerosis (dSSc), limited Systemic Sclerosis (lSSc), overlap type of Systemic Sclerosis, undifferentiated type of Systemic Sclerosis, Systemic Sclerosis sine scleroderma, skin fibrosis, scleroderma, nephrogenic fibrosing dermopathy (NFD), nephrogenic systemic fibrosis (NSF) and keloid formation. Also disclosed is the use in combination with PDE5 inhibitors. Examples of particularly preferred sGC stimulator compounds include: 2-[1-(2-Fluorbenzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine (1); Methyl-4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]-5-pyrimidinyl(methyl)carbamate (3); 4-({ (4-carboxybutyl)[2-(2-([4-(2-phenylethyl)benzyl]oxy} phenyl)ethyl]amino} methyl)carboxylic acid (5); 5-ChIoro-2-(5-chlorothiophene-2-sulfonylamino-N-(4-(morpholine-4-sulfonyl)-phenyl)benzamid sodium salt (9); 1-[6-(2-(2-Methyl-4-(4-trifluoromethoxyphenyl)benzyloxy)-phenyl)pyridine-2-yl]-5-trifluoromethyl-pyrazol-4-carboxylic acid (12); 1-({ 2-[3-Chlor-5-(trifluoromethyl)phenyl]-5-methyl-1,3-thiazole-4-yl} methyl)-1H-pyrazole-4-carboxylic acid (14); 4-Amino-2-[5-chloro-3(3,3,3-trifluororpropyl)-1H-indazol-1yl]-5,5-dimethyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidine-6-one (17); 4-Amino-5,5-dimethyl-2-[3-(2,4,6-trifluorobenzyle )imidazo[1,5-a]pyridine-1-yl]]-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidine-6-one (25); 3-(4-Amino-5-cyclopropylpyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine (27) (also known as BAY 41-2272).
Patent NZ-605149-A (NZ)
Title: Inhaler
Inventor: ARVIDSSON LARS RUNE GUSTAV
IPC: A61M15/00
Filed: 2011-07-19
Abstract: 605149 A dry powder inhaler with a disc-shaped assembly (14) having cavities filled with medicament powder for inhalation. The inhaler has a housing (6, 8) and a mouthpiece (10) mounted on the housing (6, 8), the mouthpiece (10) having an inhalation channel. The inhaler has a disc shaped assembly (14) comprising a plurality of compartments containing medicament, the disc assembly (14) being rotatably mounted to the housing (6, 8) to allow medicament-containing compartments to be brought sequentially into registry with the mouthpiece (10). The mouthpiece (10) is located at or beyond the outer periphery of the disc assembly (14) and is in communication with the disc assembly (14) via an aperture in the housing (6, 8). The mouthpiece (10) is movably mounted with respect to the housing (6, 8) and the mouthpiece (10) forms part of an indexing mechanism associated with the disc assembly (14).
Patent NZ-622869-A (NZ)
Title: Stable veterinary anthelmintic formulations
Inventor: YERITSYAN KAREN
IPC: A61K31/365
Filed: 2014-03-24
Abstract: Provided are veterinary anthelmintic formulations comprising at least one macrocyclic lactone, levamisole, dimethyl sulfoxide (DMSO) and at least one humectant. The formulations may further comprise an anthelmintic benzimidazole. Examples of the humectant include propylene glycol, hexylene glycol, butylene glycol or a sugar alcohol. One of the preferred embodiments is a veterinary formulation comprising at least one macrocyclic lactone at 0.5-1% by weight, levamisole at 10-20% calculated by weight of levamisole base, DMSO at 50-80% and at least one humectant added to volume. Further provided is a method of treating internal and/or external parasites in a non-human animal using the formulations and the use of the formulations in the manufacture of a medicament for the treatment of internal and/or external parasites in an animal.
Patent NZ-702840-A (NZ)
Title: Improvements in or relating to refrigerated display appliances
Inventor: WOOD IAN
IPC: A47F3/04
Filed: 2011-03-29
Abstract: A refrigerated display unit (1), having an open-fronted cabinet providing a product display space (3) accessible through an access opening (39) provided by the open front. Cooling means produces cold air to refrigerate items in the product display space (3). A cold air curtain is provided across the access opening (39) using a forwardly-positioned discharge outlet (5) communicating with a supply duct (45) and a forwardly-positioned return inlet (7) in communication with a return duct (41) receiving air from the air curtain (9). The air curtain (9) is substantially unsupported by any supplementary cooling airflow supplied into the product display space (3) separately from the air curtain (9).
Patent NZ-708266-A (NZ)
Title: Processing biomass and hydrocarbon-containing materials
Inventor: MEDOFF MARSHALL
IPC: C12P19/04
Filed: 2009-12-16
Abstract: Claimed is a method of extracting hydrocarbon products from hydrocarbon-containing materials, the method comprising: providing a mixture comprising a first hydrocarbon-containing material having been exposed to ionizing radiation, one or more oxidants, and one or more compounds comprising one or more naturally-occurring, non-radioactive group 5, 6, 7, 8, 9, 10 or 11 elements, the first hydrocarbon-containing material having a first peak molecular weight value; maintaining conditions effective to allow the one or more naturally-occurring, nonradioactive group 5, 6, 7, 8, 9, 10 or 11 elements to participate in a Fenton-type reaction, while initiating or sustaining a cracking reaction with one or more hydrocarbons; wherein hydroxyl radicals generated by the ionizing radiation and/or in the Fenton-type reaction then react with the first hydrocarbon-containing material to produce a second hydrocarbon-containing material having a second peak molecular weight value lower than the first peak molecular weight value; and extracting the second hydrocarbon-containing material.
Patent NZ-710319-A (NZ)
Title: Production of encapsulated nanoparticles at commercial scale
Inventor: MEISER FELIX
IPC: B02C17/00
Filed: 2010-04-23
Abstract: The present disclosure relates to methods for producing a dosage form of a solid biologically active material, comprising the steps of: dry milling a solid biologically active material, a milling aid and a millable grinding matrix in a mill, for a time period sufficient to produce particles of the biologically active material dispersed in an at least partially milled grinding matrix, wherein the average/median particle size of the milled biologically active material, determined on a particle number basis, is equal to or less than 5000nm, wherein the total combined amount of biologically active material, milling aid and grinding matrix in the mill at a given time is selected from the group consisting of equal to or greater than: 200g, 500g, 1kg, 2kg, 5kg, 10kg, 20kg, 30kg, 50kg, 75kg, 100kg, 150 kg, and 200 kg, and wherein, when tested under standard US Pharmacopeia conditions, the milled biologically active material has a dissolution profile of no less than 90% dissolution, by 15 weight, at 60 minutes and wherein the dosage form is for single or multi-dose form. Further disclosed is the dosage form produced by the method for pharmaceutical, veterinary or agricultural use.
Patent NZ-714032-A (NZ)
Title: Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow
Inventor: LEUTHNER BRIAN A
IPC: A61M5/00
Filed: 2012-04-05
Abstract: Use of a pharmaceutical composition in the manufacture of a medicament formulated for local or direct administration into a cerebral ventricle for treatment of delayed cerebral ischemia due to a brain injury in a human, the pharmaceutical composition comprising a flowable, sustained release microparticulate composition comprising a pharmaceutical carrier and a therapeutic amount of a therapeutic agent selected from: a dihydropyridine L-type voltage dependent calcium channel inhibitor, an endothelin (ET) receptor antagonist, a transient receptor potential (TRP) channel antagonist; wherein the pharmaceutical carrier comprises one or more of sodium carboxymethylcellulose, sorbitol, hyaluronic acid, or dextran; and each microparticle comprises a polymer matrix having a therapeutic agent dispersed throughout the microparticle, such that the therapeutic agent is not centrally located in a core surrounded by a coating.
Patent NZ-739742-A (NZ)
Title: Heteroaryl compounds as irak inhibitors and uses thereof
Inventor: LAN RUOXI
IPC: C07D471/08
Filed: 2016-09-16
Abstract: The present invention relates to benzimidazole derivatives of Formula (I) and pharmaceutically acceptable compositions thereof, useful as interleukin-1 receptor-associated kinase (IRAK) inhibitors.
Patent NZ-742988-A (NZ)
Title: Heating and cooling system of a modular residential building
Inventor: VASLAG ARNE
IPC: E04B1/74
Filed: 2016-11-01
Abstract: The present invention discloses a heating and cooling system of a modular residential building at least comprising: a) a building framework,b) a number of flat modules (1.0), c) a number of front elements (6.04),d) at least two gable elements (6.03),e) at least one roof element (6.02), and f) a plurality of horizontal and vertical heating and cooling canals, where the building frameworks includes fastening means (5.02) for securing the flat modules (1.0) to the building framework with a horizontal and vertical distance between neighbouring flat modules (1.0) thereby creating cavities there between where cavities are utilized as the plurality of horizontal and vertical heating and cooling canals. Sound reduction material is provided between the modules and the contact surfaces of the vertical modules. This reduces sound transmission between the modules.