baber/WOPTO huggingface dataset:
Patent EA-014552-B1 (EA)
Title: 3,7-diamino-10h-phenothiazine salts and their use
Inventor: WISCHIK CLAUDE MICHEL
IPC: A61P25/28
Filed: 2007-03-28
Abstract: This invention pertains generally to the field of phenothiazine compounds, and more particularly to certain stably reduced phenothiazine compounds, specifically, certain 3,7 diamino-10H-phenothiazine (DAPTZ) compounds of the following formulawherein: each of Rand Ris independently selected from: -H; Calkyl; Calkenyl; and halogenated Calkyl; each of Rand Ris independently selected from: -H; Calkyl; Calkenyl; and halogenated Calkyl; each of Rand Ris independently selected from: -H; Calkyl; Calkenyl; and halogenated Calkyl; each of HXand HXis independently a protic acid; and pharmaceutically acceptable salts, solvates, and hydrates thereof. These compounds are useful as drugs, for example, in the treatment of tauopathies, such as Alzheimer's disease, and also as prodrugs for the corresponding oxidized thioninium drugs (for example, methythioninium chloride, MTC).
Patent EA-019240-B1 (EA)
Title: Arylvinylazacycloalkane compounds and methods of preparation and use thereof
Inventor: SCHMITT JEFFREY DANIEL
IPC: C07D405/14
Filed: 2004-03-04
Abstract: Novel vinylazacycloalkane compounds of Formula (I) are disclosed. The compounds are ligands of various nAChRs. The compounds and their pharmaceutically acceptable salts can be used to prepare pharmaceutical compositions and/or medicaments intended to prevent or treat disorders associated with dysfunction on nAChRs, especially within the central nervous system or the gastrointestinal system. Examples of types of disorders that can be treated include neurodegenerative disorders, including central nervous system disorders such as Alzheimer's disease, cognitive disorders, motor disorders such as Parkinson's disease, drug addiction, behavioral disorders and inflammatory disorders within the gastrointestinal system. The compounds can also serve as analgesics in the treatment of acute, chronic or recurrent pain.
Patent EA-017475-B1 (EA)
Title: Method of manufacturing containers
Inventor: MYERS GARY L
IPC: B21D51/26
Filed: 2007-06-26
Abstract: The invention provides a method and a system for manufacturing a container, the method includes supplying a container having a closed bottom, a sidewall with an interior diameter and a height, and a lower body between the closed bottom and the sidewall, the lower body having a profile, into a die system comprising a container base holder having an opening with a diameter to receive the closed bottom of the container; and an interior having a lower body profile, and one or more rigid metal expansion dies, wherein at least one rigid metal expansion die of the one or more rigid metal expansion dies comprises a tip having lower body profile that cooperates with the lower body profile of the container base holder, wherein the lower body profile of the container base holder and the tip are different than the profile of the lower body of the metal container; positioning the closed bottom of the container into the opening diameter of the container base holder; moving one or more rigid metal expansion dies to travel axially within the container to radially expand the interior diameter of the sidewall to a larger interior diameter by the axial travel of the one or more rigid expansion dies, shorten the height of the sidewall and reform the profile of the lower body of the container, wherein the larger interior diameter is uniform along the height of the sidewall.
Patent EA-019954-B1 (EA)
Title: A control valve
Inventor: JORGENSEN AGNES
IPC: G05D16/06
Filed: 2009-05-04
Abstract: The control valve according to the invention is for use in liquid-carrying systems. It comprises a valve housing (1) having an inlet side (17) and an outlet side (18), said valve housing being provided with a pressure maintaining arrangement for maintaining a constant differential pressure between the inlet and outlet sides, as well as an amount control arrangement for setting the maximum flow amount through the valve and adjustment of it. The control arrangement comprises two cylinder shell elements (2 and 3) cooperating in the flow path, both having material removed from otherwise overlapping areas, thereby generating an uncovered area (25) in the flow path of the control valve. The outer cylinder shell element (3) is stationarily rotatable relative to the valve housing, while the inner cylinder shell element (2) may be rotated by means of a rotatable handle (13), whereby a larger or smaller opening (25) between the cooperating cylinder shell elements (2 and 3) may be provided. Both cylinder shell elements (2 and 3), which cooperate with the seat hole (8) of the valve housing, may also be displaced (26) in the axial direction, resulting in an increase or a decrease of the generated opening (25). Thereby, the flow amount may be adjusted prior to the presetting, e.g. by means of an actuator.
Patent EA-020133-B1 (EA)
Title: Safety bottle cap
Inventor: KLOPOCKI MAREK
IPC: B65D41/32
Filed: 2010-11-26
Abstract: The invention is related to a safety bottle cap, in particular for bottle containing alcoholic beverages. The cap is provided with elements that during first opening are destroyed in a visible manner, thereby preventing a bottle containing certain liquid from being refilled with a substitute amount of other liquid of characteristics and quality possibly differing from the original content. Further, the cap also ensures sufficient sealing and protection against accidental opening. According to the invention the cap comprises a metal cover 1 connected to a plastic body 2 consisting of two parts connected by a plurality of tearable bridges 3, whereby the upper part of the body 2 comprises a sealing element 4 to be introduced into the bottle head opening, a sealing lip 5, a plurality of peripherally located outer ribs 7, and the lower part of the body 2 is in the form of a cut tearable control ring comprising a protecting collar 10 directed at an angle to the inside of the ring, the collar 10 engaging into and snapping at an annular groove respectively formed in the bottle head outer surface. In the safety bottle cap of the invention the upper part of the body 2 is provided with a plurality of inner ribs 6 located peripherally at the inner side of the body 2 contacting the outer peripheral bottle head surface.
Patent EA-016921-B1 (EA)
Title: Method and device for filling a container
Inventor: GUSTAFSSON PER
IPC: B65B43/46
Filed: 2008-09-26
Abstract: A device for handling containers (2) of a collapsible type, comprising one or more stations (S) and a transport unit (4). The device is arranged to receive said containers (2) oriented in a first direction (P1) and the transport unit (4) is arranged to transport said containers (2) to at least one of said stations (S) by moving the containers (2) in a second direction (P2) along a curved path (6), said second direction (P2) being perpendicular to said first direction (P1). The device has a holding means provided for said at least one station (S) and located in a stationary position adjacent to the station (S) and a transfer means (18), which is provided for said at least one station (S) and carried by the transport unit (4) and which is cyclically movable along an endless path between a pick-up position (A) and a delivery position (B) located adjacent to the station (S). The transfer means (18) is arranged to pick up at least one container (2) in the pick-up position (A) and transfer said at least one container (2), in the delivery position (B), to the holding means. The invention also concerns a method for handling containers of a collapsible type in a filling machine.
Patent EA-023752-B1 (EA)
Title: Pharmaceutical composition for injections having neuroprotective, antiamnaesic, antioxidant, antihypoxic, antiischaemic activity (embodiments)
Inventor: CHELYAEVA ANASTASIYA GENNADIEVNA
IPC: A61P9/10
Filed: 2011-10-03
Abstract: The invention relates to the field of the pharmaceutical industry and medicine. The aim of the invention is to produce a pharmaceutical composition for injections based on the preparation 2-ethyl-6-methyl-3-hydroxypyridine succinate by adding in the composition the following mineral substances: potassium, magnesium, iron, zinc, and by substitutingC carbon isotopes byC carbon isotopes.
Patent EA-019700-B1 (EA)
Title: Inhibitors of pi3 kinase or mtor
Inventor: ANDREWS KRISTIN
IPC: A61K31/52
Filed: 2010-04-27
Abstract: The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt thereofmethods of treating diseases or conditions, such as cancer, using the compounds; and pharmaceutical compositions containing the compounds, wherein the variables are as defined herein.
Patent EA-019474-B1 (EA)
Title: Flaskless mold forming machine
Inventor: HADANO YUTAKA
IPC: B22C15/02
Filed: 2010-03-31
Abstract: The present invention relates to a flaskless mold forming machine capable to use match plate of different thickness. The flaskless mold forming machine comprises two molding flasks that have a matching plate sandwiched between them, the two molding flasks being positioned in a way such that one of opening ends of the molding flasks is opposed to each other and each of the other opening ends of the molding flasks is engaged with a squeezing board, whereby a pair of spaces is formed, each space being a space to produce a mold (molding space), into which spaces molding sand is filled by air through each of the openings for introducing the molding sand, disposed on a wall of each of the two molding flasks that are opposed to each other, as described above, the flaskless molding machine thus constituted molding two molds by squeezing the molding sand with the squeezing boards.
Patent EA-027259-B1 (EA)
Title: Tolerogenic nanocarriers for antigen-specific deletion of t effector cells
Inventor: FRASER CHRISTOPHER
IPC: A61K39/00
Filed: 2012-04-27
Abstract: Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering immunosuppressants and MHC Class I-restricted and/or MHC Class II-restricted epitopes that can generate tolerogenic immune responses (e.g., antigen-specific T effector cell deletion).
Patent EA-025235-B1 (EA)
Title: Steam generator primarily for a steam sauna
Inventor: MASLOV VIKTOR VALENTINOVICH
IPC: F24H7/02
Filed: 2011-11-25
Abstract: The invention provides a steam generator comprising a housing 1 with a heat exchanger 2 designed to permit the passage of a liquid and vapour phase heat-transfer agents, a means for heating the liquid heat-transfer agent for its transforming into the vapour phase heat-transfer agent comprising a means of fuel combustion with a flue 6, wherein the heat exchanger 2 has an inlet 3 for supplying the liquid heat-transfer agent and an outlet 4 for diverting the vapour phase heat-transfer agent to the object to be heated. The means for heating the liquid heat-transfer agent comprises at least two sealed tanks 10, 11, 12 connected in series downstream the flue gas passage, in each of which a propriate metal-containing heat-storage material 13, 14, 15 in a solid state is arranged. The heat exchanger 2 extends through said tanks 10, 11, 12, wherein the means of fuel combustion with the flue 6 are designed adopted to heat each heat-storage material 13, 14, 15 to the temperature of phase transition from solid to liquid state and its maintaining in the phase transition state. Each tank 10, 11, 12 is equipped with a means for controlling the phase state of appropriate heat-storage material 13, 14, 15, and in the inlet 3 of the heat exchanger 3 a sealed means in provided for supplying the liquid-transfer agent in a quantity to ensure the complete phase transition of the input liquid heat-transfer agent to the vapour phase upon heating with the heat storage material 13, 14, 15, being in said state of the phase transition.
Patent EA-025692-B1 (EA)
Title: Use of modafinil in the treatment of cocaine addicts
Inventor: SUPLIE PASCAL
IPC: A61P25/36
Filed: 2013-02-25
Abstract: The present invention relates to the use of modafinil in the substitution treatment of cocaine addicts, consisting of using a pharmaceutical composition in which said modafinil is in the form of its dextro-rotary enantiomer (S modafinil), wherein the pharmaceutical composition is absorbed via an oral route, S modafinil is obtained by the technology of the supercritical fluid, said S modafinil is absorbed at the surface of granules made in an inert support, and the dose of S modafinil absorbed by a patient is from 50 to 100 mg per unit dose.
Patent EA-029441-B1 (EA)
Title: Polysaccharide microgels for cleaning water of petroleum, petroleum products and metal ions and method for using same (variants)
Inventor: ELAGIN ANDREY ALEKSANDROVICH
IPC: E02B15/00
Filed: 2013-06-18
Abstract: The group of inventions relates to the field of organic chemistry and can be used for cleaning water, industrial and domestic waste water or waste water sediment, and for the containment and recovery of petroleum and petroleum product spills in large bodies of water, rivers, lakes and seas. The task of the present group of inventions is making it possible to recover a commercial product, recovered during the process of cleaning water of petroleum or petroleum products, and to recover the starting substance for the reuse thereof, while simultaneously simplifying the slurry utilization process. The set task is solved by that in the claimed group of inventions, aqueous solutions of polysaccharide microgels, having a molecular mass of 20000-200000 daltons and a particle size of 50-600 nm, are used as a substance for cleaning water of petroleum and petroleum products. Moreover, low concentrations of polysaccharide microgels in water, ranging from 0.1 to 20 g/l, are used, which makes is possible to economize the initial polysaccharides.
Patent EA-034753-B1 (EA)
Title: Radiopharmaceutical agent based on cyclic octapeptide and use thereof for the treatment of neoplasms which express somatostatin receptors
Inventor: NAZARENKO ANNA BORISOVNA
IPC: C07K14/655
Filed: 2014-01-23
Abstract: The invention relates to a radiopharmaceutical agent comprising a complex of radionuclidesIn,Y andLu with cyclic octapeptide, wherein a chelating group DOTA is covalently attached to an - or -amino group of N-terminal lysine (Lys). The claimed radiopharmaceutical agent is useful in the prevention and treatment of neoplasms expressing somatostatin receptors.
Patent EA-030150-B1 (EA)
Title: Emulsifiable concentrate comprising pesticide, alkyl lactate and fatty amide
Inventor: MAYER WINFRIED
IPC: A01N43/653
Filed: 2014-03-03
Abstract: Subject matter of the present invention is an emulsifiable concentrate comprising a water-insoluble pesticide in a dissolved form, a) an alkyl lactate, and b) an amide of the formula (I) R-C(O)N(R), where Ris C-C-alkyl and Ris C-C-alkyl, c) from 0.5 to 30% by weight of benzyl alcohol. The invention further relates to a process for the preparation of said concentrate; an emulsion obtainable by mixing with water a water-insoluble pesticide in a dissolved form, the components a) and b) and benzyl alcohol; and to a method for controlling phytopathogenic fungi and/or undesired vegetation and/or undesired attack by insects or mites and/or for regulating the growth of plants, where the concentrate or the emulsion is allowed to act on the respective pests, their environment or on the crop plants to be protected from the respective pests, on the soil and/or on undesired plants and/or on the crop plants and/or their environment.
Patent EA-028302-B1 (EA)
Title: Apparatus and method for producing dispersions and solids
Inventor: PENTH BERND
IPC: F26B3/12
Filed: 2014-03-28
Abstract: An apparatus and a method for producing dispersions and solids by controlled precipitation, coprecipitation and self-organising processes in a microjet reactor, wherein, correspondingly, a jet of a solvent (2) containing at least one target molecule collides with a jet of a non-solvent (3) at defined pressures and flow rates at a collision point (K) in the reactor chamber of the microjet reactor, and wherein the microjet reactor has a gas inlet (5) for admitting gas to the reactor chamber (1) and a reactant outlet (6) for discharging the reactants in a gas stream. This results in very rapid precipitation, coprecipitation or a chemical reaction in which microparticles or nanonparticles are produced. In order to provide an apparatus that can perform solvent/non-solvent precipitation in such a way as to produce particles that are as small as possible and are largely unaffected by Ostwald ripening in the resulting dispersion, the invention proposes connecting a spray-drying unit (7) to the reactant outlet and providing a control circuit (11) to optimise and maintain the operating parameters of the spray-drying unit (7).
Patent EA-030897-B1 (EA)
Title: Backlight driving circuit and liquid crystal display device
Inventor: ZHANG HUA
IPC: G09G3/36
Filed: 2013-12-06
Abstract: A backlight driving circuit and a liquid crystal display device are described. The backlight driving circuit drives at least one LED bar and includes a power supply module, a switch module, and a detection module. When the detection module detects that a positive polarity end of a power supply voltage of the power supply module is electrically coupled to a negative polarity end of the LED bar, the switch module switches the positive polarity end of the power supply voltage to be electrically coupled to the positive polarity end of the LED bar and switches a negative polarity end of the power supply voltage to be electrically coupled to a negative polarity end of the LED bar. The present invention can detect the polarities of the LED bar so that the LED bar can keep on working normally.
Patent EA-033321-B1 (EA)
Title: Device and method for high shear liquid metal treatment
Inventor: CASSINATH ZEN
IPC: B22D17/30
Filed: 2015-08-19
Abstract: The present invention provides a high shear liquid metal treatment device (1). The device (1) comprises a barrel (2), a rotor shaft (5), a plurality of rotor fans (6, 7, 8), and a plurality of stator plates (9, 10, 11). The a barrel (2) having a longitudinal axis extending between an upper end and a lower end, and having an opening (4, 3) at its upper and lower ends. The rotor shaft (5) mounted centrally through, and parallel to the longitudinal axis of, the barrel (2). The plurality of rotor fans (6, 7, 8) mounted along an axial length of the shaft (5) and within the barrel (2), each rotor fan (6, 7, 8) formed such that its outer end is within a minimum distance of an internal wall of the barrel (2). The plurality of stator plates (9, 10, 11) formed on an inner surface of the barrel (2), the stator plates (9, 10, 11) being located between adjacent rotor fans (6, 7, 8), each stator plate extending from an inner surface to substantially to the rotor shaft (5), each stator plate having at least one passage (17) formed therethrough to allow fluid to pass through the plate; and upper and lower surfaces of each stator plate are formed to be within the minimum distance of an adjacent rotor fan (6, 7, 8). The minimum distance being between 10 μm and 10 mm. The present invention also provides a method of high shear liquid metal treatment using the device (1). The present invention allows improved treatment of liquid and semi-liquid metals during processing.
Patent EA-036590-B1 (EA)
Title: Device for regenerating filters of water supply wells
Inventor: IVASHECHKIN VLADIMIR VASILIEVICH
IPC: E03B3/18
Filed: 2018-12-28
Abstract: The invention relates to water supply and can be used for regenerating filters and near-filter areas of water supply wells to remove clogging sediments. The problem solved by this invention is increasing the efficiency of destruction and extraction of solid cemented clogging sediments accumulated in wells operated for a long time, and increasing the device productivity in order to ensure its competitive capacity. The set problem is solved by a device for regenerating filters of water supply wells, comprising a working chamber (8) made as a cylinder with a cylindrical hole in its lower part; a reflector (11); a spark plug (9) mounted in the working chamber; an electrolyzer (1) with a package of electrodes (2) which are electrically connected to a DC supply (3); a gas cap with a conical bottom (13) mounted under the reflector and having gas feed and gas discharge pipes (6) and (7); sealing collars (10) installed on the side surface of working chamber and gas cap (12), wherein the device further includes a reagent tank (14) with a dosing unit (15) installed at the well head; an annular perforated tube for reagent distribution (18) installed in the lower part of the working chamber and connected to the dosing unit by a reagent hose (17); an additional spark plug (21) installed in the cavity of the gas cap, the electrolyzer being located at the well head and equipped with a safety shutter (4) which is connected to the gas feed pipe (6) by a gas supply hose (5).
Patent EA-035229-B1 (EA)
Title: Corrosion-protected reformer tube with internal heat exchange
Inventor: HASSLER NATHANAEL
IPC: C01B3/38
Filed: 2017-06-27
Abstract: A reformer tube for producing synthesis gas by steam reforming of hydrocarbon-containing input gases is proposed where an outer shell tube is divided by means of a separating tray into a reaction chamber and an exit chamber, a dumped bed of a steam-reforming-active solid catalyst is arranged in the reaction chamber, at least one heat exchanger tube is arranged inside the reaction chamber and inside the dumped catalyst bed, whose entry end is in fluid connection with the dumped catalyst bed and whose exit end is in fluid connection with the exit chamber, the exit end of the heat exchanger tube is fed through the separating tray and opens out into a corrosion-protected inner tube which is disposed in the interior of the shell tube and is in fluid connection with a collection conduit for the synthesis gas product, a gas-permeable thermal insulation layer is arranged between the inner wall of the shell tube and the outer wall of the inner tube.
Patent EA-037376-B1 (EA)
Title: CONDENSED THIOPHENE DERIVATIVES USEFUL AS NAPi-IIB INHIBITORS
Inventor: COATES DAVID ANDREW
IPC: A61K31/4995
Filed: 2017-08-08
Abstract: The invention provides a compound of formulapharmaceutically acceptable salts thereof, a pharmaceutical composition and a solid dispersion formulation thereof for treating a condition associated with NaPi-IIb activity, methods of treating hyperphosphatemia and/or chronic kidney disease providing the use of said compound, as well as the use thereof as prescribed above.
Patent EA-036978-B1 (EA)
Title: Wireless guest engagement system
Inventor: PADGETT JOHN
IPC: H04W12/08
Filed: 2017-05-17
Abstract: A guest engagement system and associated methods provide seamless engagement with guests of facilities through the use of wireless sensing technologies. The system makes use of individual guest devices which are carried by guests and used to automatically identify and authenticate the guests throughout the facility. Services can thereby be seamlessly provided to the guests throughout the facility. The services include automatic unlocking of doors, including hotel or state room doors, based on the guests' immediate proximity to their assigned room's door. The services also include automated payment services provided at checkout or vending terminals, and automated log-on to interactive displays and portals, among others, based on secure wireless authentication of the guest devices.