baber/WOPTO huggingface dataset:
Patent AU-2014367550-B2 (AU)
Title: Nucleic acid inducing RNA interference modified for preventing off-target, and use thereof
Inventor: CHI SUNG WOOK
IPC: A61K48/00
Filed: 2014-12-08
Granted: 2018-04-19
Abstract: The present invention relates to a nucleic acid inducing RNA interference and a use thereof, and more specifically, to a nucleic acid inducing RNA interference, modified by replacing, by a spacer capable of no base pairing, 5' terminal and 3' terminal regions in at least one single strand of the double strand of the nucleic acid inducing RNA interference. The nucleic acid inducing RNA interference of the present invention can provide: a nucleic acid having a novel modified form for preventing an off-target effect generated when inhibiting the expression of a target gene by an RNA interference phenomenon; and a method for selectively inhibiting the expression of a target gene by using the same. In addition, the nucleic acid inducing RNA interference according to the present invention solves the inaccuracy and side effects due to off-target, which are the problems of a known nucleic acid inducing RNA interference, by providing a nucleic acid inducing RNA interference as a novel modified form having target selectivity and specificity by preventing an off-target effect while inhibiting the expression of a target gene, and thus can be used, without worries, in the research of a technique for inhibiting the expression of a gene and in gene therapy.
Patent AU-2015201454-B2 (AU)
Title: Patient positioning support structure with trunk translator
Inventor: JACKSON ROGER P
IPC: A61G13/02
Filed: 2015-03-19
Granted: 2018-03-29
Abstract: A patient support structure includes a pair of independently height-adjustable supports, each connected to a patient support. The supports may be independently raised, lowered, rolled or tilted about a longitudinal axis, laterally shifted and angled upwardly or downwardly. Position sensors are provided to sense all of the foregoing movements. The sensors communicate data to a computer for coordinated adjustment and maintenance of the inboard ends of the patient supports in an approximated position during such movements. A longitudinal translator provides for compensation in the length of the structure when the supports are angled upwardly or downwardly. A patient trunk translator provides coordinated translational movement of the patient's upper body along the respective patient support in a caudad or cephalad direction as the patient supports are angled upwardly or downwardly for maintaining proper spinal biomechanics and avoiding undue spinal traction or compression.
Patent AU-2015207691-B2 (AU)
Title: Induction supply air terminal unit with increased air induction ratio, method of providing increased air induction ratio
Inventor: PAHWA DEEPAK
IPC: F24F1/01
Filed: 2015-01-15
Granted: 2018-08-02
Abstract: The present invention relates to an induction supply air terminal device where primary air flow is used to induce a secondary air flow wherein the nozzles are provided in the form of a cluster arrangement, comprising one or more clusters of three or more nozzles each. The clusters can be arranged according to predetermined patterns depending on the pattern of air induction that is desired.
Patent AU-2015208397-B2 (AU)
Title: Injector training device
Inventor: BENDEK ANTONIO
IPC: G09B23/28
Filed: 2015-01-14
Granted: 2017-08-10
Abstract: An auto-injection training device is presented that allows a user to simulate an injection procedure that occurs with a real-life commercial auto-injector containing a prefilled container of medicament. The training device is resettable, thus allowing the user to perform multiple simulations. Each simulation provides both audible and visual signals to the user that the injection procedure is in progress.
Patent AU-2015237857-B2 (AU)
Title: Spray-dried solid-in-oil-in-water dispersions for inhalation of active pharmaceutical ingredients
Inventor: HUANG DANIEL
IPC: A61K9/00
Filed: 2015-03-24
Granted: 2017-08-10
Abstract: Embodiments of the invention relate to particulate agents and compositions comprising particulate agents for inhalation, and methods for preparing such particulate agents and compositions for inhalation, as well as therapeutic methods. Embodiments of the method comprise preparing an emulsion by combining an oil phase dispersion of hydrophobic seed particles and an aqueous dispersion comprising an emulsifier and an emulsion stabilizer and preparing a feedstock comprising encapsulated particles by homogenizing the emulsion, and forming a plurality of coated particles by spray drying the feedstock, wherein resulting particles comprises a porous shell disposed on or over a core and the core comprises at least one hydrophobic seed particle.
Patent AU-2015247468-B2 (AU)
Title: Low toxicity solvent system for polyamideimide and polyamide amic acid resin coating
Inventor: KELLY CARISSA M
IPC: C08G73/14
Filed: 2015-04-16
Granted: 2019-02-14
Abstract: A polyamideimide and polyamide amic acid resin polymer that allows for reduced levels of toxicity in manufacturing. In an embodiment, a coating composition comprises at least one polyamideimide resin, at least one aprotic dialkylamide solvent and at least one co-solvent. In another embodiment, the at least one co-solvent is selected from a group consisting of methyl actetate, n-propyl acetate, t-butyl acetate, iso-butyl acetate, ethyl acetate, isopropyl acetate, methyl lactate, ethyl lactate, n-propyl lactate, isopropyl lactate, n-butyl lactate, isobutyl lactate, t-butyl lactate, cyclohexanone, cyclopentanone, n-butyl acetate, methyl alcohol, ethyl alcohol, isopropyl alcohol, n-acetyl morpholine, ?-caprolactone and methylcyclohexane.
Patent AU-2015261590-B2 (AU)
Title: Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone
Inventor: CHAPMAN ROBERT
IPC: C07D489/00
Filed: 2015-11-25
Granted: 2017-04-20
Abstract: PROCESS FOR PREPARING OXYCODONE HYDROCHLORIDE HAVING LESS THAN 25 PPM 14-HYDROXYCODEINONE Abstract Oxycodone is a semi-synthetic opioid analgesic that exerts an agonist effect at specific, saturatable opioid receptors in the CNS and other tissues. 14-hydroxycodeinone is an impurity formed in the production of oxycodone from thebaine. The invention provides a purified oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and processes for its production.
Patent AU-2015305543-B2 (AU)
Title: Adjustable free-float forend/handguard mounting assembly
Inventor: DZWILL ALEXANDER EDWARD
IPC: F41A21/48
Filed: 2015-08-19
Granted: 2018-05-31
Abstract: An adjustable free-float forend/handguard mounting assembly for a small arms weapon, for attaching a forend/handguard to the small arms weapon. The assembly includes a barrel nut having internal female threads at a forward end and internal female threads at an opposite rearward end and having a plurality of radial utility holes. The assembly further includes a jam ring having internal cylindrical surfaces and having a plurality of threaded radial mounting holes, a washer, and a jam bolt having a hollow cylindrical body with a rearwardly extending externally male threaded portion and a forward external collar portion. The jam ring is rotatingly supported on its internal cylindrical surfaces for free rotation about the male threaded portion and the forward external collar portion of the jam bolt. The washer and the jam ring have similar internal diameters and are each similarly mounted on the jam bolt. The rearwardly extending externally male threaded portion of the jam bolt is adapted to engage with the internal female threads at the forward end of the barrel nut.
Patent AU-2015326210-B2 (AU)
Title: Absorbent article
Inventor: SUGIYAMA KATSUHIKO
IPC: A61F13/49
Filed: 2015-09-25
Granted: 2018-01-25
Abstract: This absorbent article (10) comprises a liquid-permeable top sheet (14), a liquid-impermeable back sheet (12), and an absorber (13) disposed between the top sheet and the back sheet. The absorbent article (10) further comprises a first recessed portion (20a) which is formed on a surface of the absorber opposing the top sheet and extends along a first direction, and a second recessed portion (20b) which is formed on the surface of the absorber opposing the top sheet so as to intersect the first recessed portion and extends along a second direction that is different from the first direction. The first recessed portion and the second recessed portion each have a first region (201) where the depth from the surface of the absorber to the bottom of the recessed portion is shallow, and a second region (202) where the depth from the surface of the absorber to the bottom of the recessed portion is deeper than the first region.
Patent AU-2015349782-B2 (AU)
Title: Therapeutic variant alpha-2-macroglobulin compositions
Inventor: HANNA LEWIS
IPC: A61K38/41
Filed: 2015-11-20
Granted: 2020-08-13
Abstract: A2M polypeptide compositions containing a non-natural bait region are disclosed. Methods of producing wild-type and variant A2M polypeptides and polynucleotides containing a non-natural bait region are also disclosed. The bait regions of the variant A2M polypeptides demonstrate enhanced protease inhibitory characteristics compared to wild-type A2M.Variant A2M polypeptides that demonstrate longer half-lives upon administration to an organism compared to wild-type A2M are disclosed. The A2M compositions are useful in treating a number of diseases and conditions including inflammation, chronic wounds, and diseases with a pathology associated with proteases.
Patent AU-2015360472-B2 (AU)
Title: Weighted subsymbolic data encoding
Inventor: MAJUMDAR ARUN
IPC: G06F16/35
Filed: 2015-12-10
Granted: 2021-07-01
Abstract: Described herein is a method and system of geometrically encoding data including partitioning data into a plurality of semantic classes based on a dissimilarity metric, generating a subspace formed by first and second data elements, the first and second data elements being included in first and second numbers of partitioned semantic classes, encoding the first data element with respect to the second data element such that the generated subspace formed by the first data element and the second data element is orthogonal, computing a weight distribution of the first data element with respect to the second data element, the weight distribution being performed for each of the first number of semantic classes and the second number of semantic classes, and determining a dominant semantic class corresponding to an ordered sequence of the first data element and the second data element, the dominant semantic class having a maximum weight distribution.
Patent AU-2015373475-B2 (AU)
Title: Process for separation of gases with reduced maintenance costs
Inventor: PRISKE MARKUS
IPC: B01D53/22
Filed: 2015-12-22
Granted: 2020-05-07
Abstract: The invention relates to a specific process and apparatus for separation of gas mixtures with reduced maintenance costs.
Patent AU-2016222302-B2 (AU)
Title: Adhesion control system and method
Inventor: WORDEN BRET DWAYNE
IPC: B61C15/14
Filed: 2016-08-29
Granted: 2018-08-30
Abstract: ADHESION CONTROL SYSTEM AND METHOD A system includes an air source for supplying compressed air on board a vehicle having a wheel that travels on a route. A nozzle is fluidly coupled to the air source and is configured to direct a flow of compressed air from the air source to a contact surface of the route. A valve is positioned intermediate the air source and the nozzle and is controllable between a first state in which the compressed air flows from the air source to the nozzle, and a second, disabled state in which the compressed air is prevented from flowing to the nozzle. A controller controls the valve between the first state and the second, disabled state. An operator interface is electrically coupled to the controller and includes a momentary disable switch biased to a position that controls the valve to the first state and movable against the bias to control the valve to the second, disabled state.
Patent AU-2016265457-B2 (AU)
Title: Antisense oligonucleotides to treat dystrophic epidermolysis bullosa
Inventor: HAISMA ELISABETH MARLENE
IPC: C12N15/113
Filed: 2016-05-20
Granted: 2022-06-09
Abstract: An antisense oligonucleotide capable of preventing or reducing exon 80 inclusion into a human COL7A1 mRNA, and methods for preventing or reducing exon 80 inclusion into a human COL7A1 mRNA.
Patent AU-2016277645-B2 (AU)
Title: Method for altering plasma retention and immunogenecity of antigen-binding molecule
Inventor: IGAWA TOMOYUKI
IPC: C12N1/19
Filed: 2016-12-21
Granted: 2019-04-04
Abstract: The present invention demonstrated that the modification of the Fc region of an antigen-binding molecule into an Fc region that does not form in a neutral pH range a 5 heterotetramer complex containing two molecules of FcRn and an active Fcy receptor improved the pharmacokinetics of the antigen-binding molecule and reduced the immune response to the antigen-binding molecule. The present invention also revealed methods for producing antigen-binding molecules having the properties described above, and successfully demonstrated that pharmaceutical compositions containing as an active ingredient such an antigen-binding 0 molecule or an antigen-binding molecule produced by a production method of the present invention have excellent features over conventional antigen-binding molecules in that when administered, they exhibit improved pharmacokinetics and reduced in vivo immune response.
Patent AU-2016315661-B2 (AU)
Title: Providing safety related contextual information in a personal protective equipment system
Inventor: BAHNERS MICHAEL
IPC: G06F9/52
Filed: 2016-08-29
Granted: 2019-08-15
Abstract: A personal protection equipment (PPE) system with a remote user interface comprises an article of PPE including an active wireless communication device for transmitting a signal and a controller for managing settings on the article of PPE; and a communication hub including a user interface, an electronic connection to a PPE management software, and a wireless communication device. When the wireless communication device of the communication hub detects that the article of PPE is in proximity to the communication hub, the hub displays information on the user interface. The user interface displays settings for the article of PPE, and the settings can be adjusted by a user through interaction with the user interface. The wireless communication device of the communication hub transmits information related to the adjusted settings to the wireless communication device of the article of PPE; and the controller adjusts the settings on the article of PPE.
Patent AU-2016387204-B2 (AU)
Title: Method for the production of a dental structure, produced dental structure and dental assembly formed by a structure screwed onto a dental implant
Inventor: XAM-MAR MANGRANE ESTEBAN
IPC: A61C8/00
Filed: 2016-01-21
Granted: 2021-03-04
Abstract: The invention relates to a method for producing a dental structure intended for being positioned and screwed onto a previously osteointegrated dental implant, as well as to the structure produced according to the method and to the dental assembly formed by said structure and the implant.
Patent AU-2016418249-B2 (AU)
Title: Tray system for transfer, counting, storage and disposal of surgical instruments
Inventor: HART CHRISTOPHER ALEXANDER
IPC: A61B50/33
Filed: 2016-12-13
Granted: 2023-07-27
Abstract: DNCP-100WO 
ABSTRACT 
The present invention provides a transfer tray for transferring one or 
more surgical instruments securely. The present invention further provides a counting 
tray for the collection and securing of used surgical instruments. Additionally, the 
present invention provides a surgical instrument disposal container comprising a 
transfer tray coupled to a counting tray such that used surgical instruments are 
enclosed within the counting tray by the transfer tray.
Patent AU-2017202512-B2 (AU)
Title: Pyrazolyl quinoxaline kinase inhibitors
Inventor: SAXTY GORDON
IPC: C07D487/08
Filed: 2017-04-18
Granted: 2018-07-26
Abstract: Abstract The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said 5 compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Patent AU-2017204014-B2 (AU)
Title: Low-Flow Emitter
Inventor: WANG DANIEL CHUN
IPC: A01G25/02
Filed: 2017-06-14
Granted: 2018-11-01
Abstract: A low-flow emitter (10) includes a rotatable cap (20) and a body (30). The rotatable cap (20) has a threaded hole (25) and a receiving chamber (26) communicating with the 5 threaded hole (25). The wall of the receiving chamber (26) has plural grooves (28), which are annularly arranged in a spaced manner around the threaded hole (25). The body (30) has a shaft (31). The shaft (31) has an external thread (35) and a flexible rib (38) adjacent to the external thread (35) and is connected to the rotatable cap (20) by threaded connection between the external thread (35) and the threaded hole (25) such that the 10 flexible rib (38) is engaged in one of the grooves (28). When the rotatable cap (20) is rotated to adjust the amount of water delivered by the low-flow emitter (10), the area of contact between the grooves (28) of the rotatable cap (20) and the flexible rib (38) of the body (30) stays unchanged, allowing the rotatable cap (20) to produce a consistent feel to the operator. >0
Patent AU-2017204337-B2 (AU)
Title: Stable and soluble antibodies inhibiting vegf
Inventor: BORRAS LEONARDO
IPC: A61K39/395
Filed: 2017-06-27
Granted: 2019-05-16
Abstract: The present invention relates to soluble and stable anti-VEGF immunobinders comprising CDRs from rabbit monoclonal antibodies. Said antibodies are designed for the diagnosis and/or treatment of VEGF-mediated disorders. The hybridomas, nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed.
Patent AU-2017216956-B2 (AU)
Title: Seamless relocation of a mobile terminal in a wireless network
Inventor: WANG LEI
IPC: H04W36/00
Filed: 2017-02-02
Granted: 2019-07-25
Abstract: A method for performing seamless relocation of a mobile terminal in a wireless network includes selecting a first serving gateway (SGW) among a plurality of SGWs and a first packet data network gateway (PGW) among a plurality of PGWs, wherein the first SGW connects to the first PGW to setup the first S5 session, establishing a first communication channel between the terminal and the first PGW and assigning an internet protocol (IP) address to the terminal, selecting a second SGW among the plurality of SGWs when the terminal is about to move out of an area being served by the first SGW, connecting the second SGW to the second PGW to setup a new S5 session when a second PGW among the plurality of PGWs is closer to the second SGW than the first PGW or connecting the second SGW to the first PGW to modify the first S5 session when no PGW is closer to the second SGW than the first PGW, establishing a second communication channel between the terminal and the second SGW using the IP address allocated to the terminal, reconfiguring routing for terminal IP destination, and terminating the first communication channel between the terminal and the first PGW.
Patent AU-2017220970-B2 (AU)
Title: Pharmaceutical composition containing imidazoline derivative
Inventor: LU YUN
IPC: A61K31/4166
Filed: 2017-02-17
Granted: 2021-12-16
Abstract: Provided in the present invention is a pharmaceutical composition containing an imidazoline derivative. In particular, the pharmaceutical composition provided in the present invention contains (S)-4-(3-(4-(2,3-dihydroxypropoxy) phenyl)-4,4-dimethyl-5-carbonyl-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl) benzonitrile and cellulose ether; the composition has good stability, dissolution rate and bioavailability.
Patent AU-2017268501-B2 (AU)
Title: Aerosol generating material and devices including the same
Inventor: JOHN EDWARD
IPC: A24F40/46
Filed: 2017-11-28
Granted: 2019-02-28
Abstract: Abstract There is provided a device for generating an inhalable aerosol and/or gas, the device comprising an aerosol generating material having an integrated electrical resistance 5 heating element, so that the aerosol generating material may be heated in direct contact with the electrical resistance heating element, wherein the aerosol generating material is provided as a unitary structure and/ or coating which may be heated to generate multiple deliveries of an inhalable aerosol and/or gas. There is also provided a method for fabricating the device. There is also provided the use of the device and the use of the 10 aerosol generating material, to generate an inhalable aerosol and/or gas.
Patent AU-2017316965-B2 (AU)
Title: Bicyclic nitrogenated heterocyclic compound
Inventor: NAKAJIMA TATSUO
IPC: A61P35/00
Filed: 2017-08-25
Granted: 2020-09-10
Abstract: The present invention provides: a novel use of a specific bicyclic nitrogenated heterocyclic compound as a PDE7 inhibitor; a novel bicyclic nitrogenated heterocyclic compound having a PDE7 inhibition activity, a method for producing the compound, a use of the compound, and a pharmaceutical composition containing the PDE7 inhibitor or the compound; and others. More specifically, the present invention provides a PDE7 inhibitor containing, as an active ingredient, a compound represented by formula (I) [wherein the symbols have the same meanings as those described in the description] or a pharmacologically acceptable salt thereof.
Patent AU-2018201889-B2 (AU)
Title: Topical formulation for a jak inhibitor
Inventor: PARIKH BHAVNISH
IPC: A61K47/10
Filed: 2018-03-16
Granted: 2020-03-05
Abstract: This invention relates to pharmaceutical formulations for topical skin application comprising (R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1 yl]propanenitrile, or a pharmaceutically acceptable salt thereof, and use in the treatment of skin disorders. PARABEN PHASE PropyleneGyo AQUEOUS PHASE Methyl Paraben ix NF Purified Water Propyl Paraben NF 4Mix Edetate Disodium Polyethylene Glycol USP Mix ACTIVE PHASE API hoshateMixXANTHAN Propylene Glycol Light Mieral Oil F eUSP Glyceryl StearateX Polysorbate 20 NF Mx/Heat White Petrolatum i ___.:::Mix Cetyl Alcohol NF Emulsify Stearyl Alcohol NF Peoytao Dimethicone 360 t t Mix /Cool Medium Chainj Triglycerides In Process Test Content Uniformity Topical formulation SFill in Tubes
Patent AU-2018204512-B2 (AU)
Title: Containers and methods for isolating liquids prior to dispensing
Inventor: DE CLEIR PIARAS VALDIS
IPC: B65D47/20
Filed: 2018-06-21
Granted: 2019-09-12
Abstract: A container for isolating a first liquid and a second liquid prior to dispensing, the container comprising: a first enclosed body for containing the first liquid and having a first body access opening; a second enclosed body for containing the second liquid and having a second body access opening, the second body access opening being adjacent to the first body access opening; a common cap secured to at least one of the first and second bodies, the common cap having a first dispensing opening and a second dispensing opening; and an insert positioned between the access openings of the first and second bodies and the common cap, the insert defining a first dispensing path having an upstream entrance in fluid communication with the first body access opening and a downstream exit in fluid communication with the first dispensing opening and a second dispensing path having an upstream entrance in fluid communication with the second body access opening and a downstream exit in fluid communication with the second dispensing opening, each of the dispensing paths having a valve movable between a closed configuration restricting flow through the valve and an open configuration permitting flow through the valve in response to pressure within each of the respective enclosed bodies.