baber/WOPTO huggingface dataset:
Patent AU-2018254426-A1 (AU)
Title: A system and a method for using a novel electrocardiographic screening algorithm for reduced left ventricular ejection fraction
Inventor: CHUGH SUMEET S
IPC: A61B5/0452
Filed: 2018-04-17
Abstract: A system and a method for identifying a patient with a threshold number of distinct ECG abnormalities. The system and the method include an ECG monitoring device; a server; a database; a network; a memory containing machine readable medium comprising a machine executable code having stored thereon instructions for identifying patients with a threshold number of distinct ECG abnormalities; and a processor coupled to the memory, the processor configured to execute the machine executable code to cause the processor to: receive an ECG data output from the ECG monitoring device; process the ECG data output to identify abnormalities in the ECG data; and analyze the abnormalities in the ECG data in order to output an indication of whether the patient has depressed LVEF, wherein the ECG monitoring device, the server, the database, the memory, and the processor are coupled to the network via communication links.
Patent AU-2018269711-A1 (AU)
Title: Self-righting systems and related components and methods
Inventor: TRAVERSO CARLO GIOVANNI
IPC: A61M5/00
Filed: 2018-05-17
Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self- righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject).
Patent AU-2018294254-A1 (AU)
Title: Synthesis of omecamtiv mecarbil
Inventor: CAILLE SEBASTIEN
IPC: C07D213/75
Filed: 2018-06-29
Abstract: Provided herein is a synthesis for omecamtiv mecarbil dihydrochloride hydrate and various intermediates. (I)
Patent AU-2018296568-A1 (AU)
Title: Enrichment of targeted genomic regions for multiplexed parallel analysis
Inventor: KOUMBARIS GEORGE
IPC: C12Q1/6886
Filed: 2018-07-06
Abstract: The invention provides improved methods for enriching targeted genomic regions of interest to be analyzed by multiplexed parallel sequencing. The methods of the invention utilize a pool of TArget Capture Sequences (TACS), wherein the pool comprises a plurality of TACS families, each member of a family binding to the same target sequence but with different start and/or stop positions on the sequence (i.e., staggered binding of the family members to the target sequence) to thereby enrich for target sequences of interest, followed by massive parallel sequencing and statistical analysis of the enriched population. The methods of the invention can be used for a variety of clinical purposes, including non-invasive prenatal testing for chromosomal abnormalities, for example using a maternal blood sample or a sample of fetal cells, assessment of maternal and paternal carrier status for genetic disorders and detection of tumor biomarkers (e.g., liquid biopsy). Kits for carrying out the methods of the invention are also provided.
Patent AU-2018312836-A1 (AU)
Title: Novel heterocyclic compounds as CDK8/19 inhibitors
Inventor: MINDICH ALEKSEI LEONIDOVICH
IPC: A61K31/4375
Filed: 2018-07-30
Abstract: The present invention relates to novel compounds of formula (I), or a pharmaceutically acceptable salt or stereoisomer thereof, which exhibit the properties of a CDK 8/19 inhibitor. The invention also relates to a pharmaceutical composition containing said compounds and to the use thereof as pharmaceutical drugs for treating diseases or disorders.
Patent AU-2018329155-A1 (AU)
Title: Closure
Inventor: DRUITT RODNEY
IPC: B65D41/04
Filed: 2018-08-31
Abstract: The invention is directed to a closure (1) having a base (3) with a top deck (4) and a therewith adjacent skirt (5) extending in an axial direction (z) comprising an internal thread (6). The closure (1) is comprising a sealing arrangement (16) with an inner seal (18) extending in the axial direction (z) from the top deck (4). The inner seal (18) is having an inner annular sealing surface (29) arranged radially inward with respect to an outer seal (17) and pointing in an outward direction. The sealing arrangement further comprises an outer seal (17), which in its cross-section comprises a base section (20) extending in the axial direction (z) from the top deck (4) and an end section (21), which is bend inwardly with respect to the course of the base section (20) in the direction of the inner seal (18) and which terminates in a sealing surface (22) pointing in an inward direction.
Patent AU-2018329866-A1 (AU)
Title: Sensor arrangement
Inventor: FOSTER SCOTT
IPC: H04J14/02
Filed: 2018-09-06
Abstract: A fiber optic sensor arrangement is disclosed that includes a plurality of optical fiber based sensor elements, the sensor elements configured to modify an associated optical carrier signal in accordance with changes in a sensed quantity at a location of the sensor element and a phase modulation arrangement for phase modulating each optical carrier signal in accordance with respective uncorrelated pseudorandom binary sequence signals. The sensor arrangement also includes an interferometer module for receiving each of the phase modulated optical carrier signals, the interferometer module operable to convert a change in the phase modulated optical carrier signals to a change in optical intensity of the corresponding optical carrier signal to generate a combined modulated optical intensity signal, an optical intensity detector for measuring the combined modulated optical intensity signal and generating a time varying electrical detector signal and an analog to digital convertor to convert the time varying electrical detector signal to a time varying digitized detector signal. Also included in the sensor arrangement is a decorrelator arrangement for decorrelating the time varying digitized detector signal against the respective uncorrelated pseudorandom binary sequence corresponding to each of the optical carrier signals to recover each of the modulated optical carrier signals and a demodulator for demodulating each of the modulated optical carrier signals to recover the respective optical carrier signal to determine the changes in the sensed quantity at the location of the sensor element.
Patent AU-2018334694-A1 (AU)
Title: Pallet module and associated modular pallet system
Inventor: VITTORIA FRANK
IPC: B65D19/26
Filed: 2018-08-29
Abstract: A modular pallet system (100) for supporting or holding goods for transportation and/or storage. The system (100) includes a plurality of pallet modules (1) that are provided with a joining mechanism (8). The joining mechanism (8) includes an elongated latching member (9) that is slidable between a retracted position and an extended position. In the extended position the latching member (9) engages in an adjacent pallet module (1).
Patent AU-2018344896-A1 (AU)
Title: Posture adaptive work chair
Inventor: EGA VENKATESHWARLU
IPC: A47C1/026
Filed: 2018-10-04
Abstract: The present subject matter relates to a work chair which adapts to dynamic body postures of a user. The posture adaptive work chair comprising a seat sub-assembly (102) having a front edge (138) and a seat base sub-assembly (124); a pair of a spine members (106) cantilevered from the font edge (138) of the seat sub-assembly (102); a back sub-assembly (104) supported by the pair of spine members (106), the back sub-assembly (104) is configured to flex in multiple axes based on direction of load applied by a user; and a tilt limit lever (120) movably coupled to the seat base sub-assembly (124); said tilt limit lever (120) being configured to enable tilting of the back-sub assembly (104) to a plurality of tilt positions ( 132, 132', 132").
Patent AU-2018364702-A1 (AU)
Title: Systems and methods for production and separation of hydrogen and carbon dioxide
Inventor: ALLAM RODNEY JOHN
IPC: F25J3/06
Filed: 2018-11-09
Abstract: The present disclosure relates to systems and methods useful for providing one or more chemical compounds in a substantially pure form. In particular, the systems and methods can be 5 configured for separation of carbon dioxide from a process stream, such as a process stream in a hydrogen production system. As such, the present disclosure can provide systems and method for production of hydrogen and/or carbon dioxide.
Patent AU-2018368617-A1 (AU)
Title: Hull device
Inventor: REYNARD FRANÇOIS
IPC: B63G13/02
Filed: 2018-11-19
Abstract: The invention relates to a hull device designed to be reversibly attached to an outer surface of a ferromagnetic structure of a marine or submarine system or vessel. The device comprises at least one attachment surface (20) suitable for attaching the device to the structure, and a plurality of permanent magnets (24) arranged in the vicinity of the attachment surface (20) in order to attach the device to the structure.
Patent AU-2018395525-A1 (AU)
Title: Systems and methods for treating biological fluids
Inventor: CHURCH DANIEL
IPC: B01J19/12
Filed: 2018-12-28
Abstract: Provided are systems and methods for treating a biological fluid, e.g., to inactivate pathogens.
Patent AU-2018438636-A1 (AU)
Title: Apparatus, system, and method for steering an implantable medical device
Inventor: CATO MILTON C
IPC: A61F2/95
Filed: 2018-08-31
Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems and methods that include an implantable medical device an actuation line configured to steer the implantable medical device. The apparatuses, systems and methods may also include a releasable knot including portions of a tether to couple the actuation line to the implantable medical device.
Patent WO-2019218030-A1 (WO)
Title: Connector device
Inventor: EDWARDS SIMON
IPC: B65D77/06
Filed: 2019-05-17
Abstract: Various aspects of the invention described herein relate to a removable connector assembly, and methods of use and manufacture thereof. More particularly, certain embodiments relate to apparatus and methods to provide a connection to a spout disposed upon a container, such as upon a bag holding fluid. Embodiments of connector assemblies comprise an elongated outer housing, an inner housing, and a slider assembly for moving the outer surface of the sleeve member over the inner surface of the outer housing wall in a lengthwise motion to position the spout connector upon the spout and secure the spout connector in said position.
Patent WO-2019222795-A1 (WO)
Title: Drilling fluids and uses thereof
Inventor: MOSTOFI MASOOD
IPC: C09K8/24
Filed: 2019-05-20
Abstract: The present invention relates to drilling fluids which reduce fluid and cutting loss during the drilling of subterranean wells. More specifically, the drilling fluids disclosed herein comprise natural and synthetic polymer blends that are effective to provide the fluid with a high viscosity under low shear rates and a low viscosity under high shear rates. The present invention also relates to methods for using the drilling fluids for reducing fluid and cutting loss during drilling.
Patent AU-2019200876-A1 (AU)
Title: Panobinostat dosages for multiple myeloma
Inventor: LIN RONG
IPC: A61K31/69
Filed: 2019-02-08
Abstract: Treatment of multiple myeloma with a combination of panobinostat and bortezomib at specified doses adjusted for safety. * A Censanng Times .. 0 2 4 6 8 10 12 14 i 18 20 22 24 26 28 30 Time (months) Figure 1 WO 2016/132303 PCT/IB2016/050850 -------------~~~~~~- ------------ ----- ------------------------------ c ia 1 u2 ut a e Fc .zur :I onmcths) Figure 1
Patent AU-2019201999-A1 (AU)
Title: A coffee cup capable of making coffee
Inventor: LIN SHICHANG
IPC: A47G19/14
Filed: 2019-03-22
Abstract: This invention discloses a coffee cup capable of automatically making coffee, including a cup 
body 10, a cup lid 11, a rotation cavity 12, a rotating block 13, a groove 14; a spline shaft 15 
which is in spline connection with the rotating block 13 is slidably connected with and 
arranged in the groove 14. Coffee beans are naturally cracked by the extruding and grinding 
between the grinding plate and the coffee beans, so that the coffee is more delicious; in 
addition, the grinding and brewing processes of the coffee beans are continuous, thereby 
reducing the oxidation and deterioration of the ground coffee when being exposed to the air, 
and keeping the flavor of the coffee; furthermore, the coffee cup is convenient to carry and 
use.
1/3 
DRWAINGS 
1 1 141 14 1 17 
+IA A + + I-- + ±+ + 
- 21-A- + 
Figre
Patent AU-2019202459-A1 (AU)
Title: Treatment of alzheimer's disease subpopulations with pooled immunoglobulin g
Inventor: GELMONT DAVID M
IPC: A61K39/00
Filed: 2019-04-09
Abstract: The present invention provides, among other aspects, methods for the treatment of Alzheimer's disease in a subject in need thereof, the method including administration of a therapeutically effective amount of a pooled human immunoglobulin G (IgG) composition to a subject with moderately severe Alzheimer's disease, a subject carrying an ApoE4 allele, or both, where the amount of pooled human IgG is from 300 mg/kg to 800 mg/kg body weight of the subject per two week period, and where the amount is administered in one or more doses during the two week period after initiation of a therapeutic regimen. Also provided, are methods for selecting a treatment regimen for a subject with Alzheimer's disease, including diagnosing the severity of the Alzheimer's disease, determining if the subject carries an APOE4 allele, or both, and assigning a treatment regimen including administration of pooled human immunoglobulin G and/or an anti-beta amyloid monoclonal antibody.
Patent AU-2019214358-A1 (AU)
Title: Modified lipidated Relaxin B chain peptides and their therapeutic use
Inventor: DUCLOS OLIVIER
IPC: C07K14/64
Filed: 2019-01-30
Abstract: The present invention relates to a biologically active single chain Relaxin peptide having the following formula (I): N
Patent AU-2019219236-A1 (AU)
Title: Zirconium and titanium phosphate coatings for implants and other substrates
Inventor: KJELLIN PER
IPC: A61L27/56
Filed: 2019-02-08
Abstract: This invention is directed to coated substrates, wherein the coating comprises titanium phosphate and/or zirconium phosphate. In certain embodiments the substrate is an implant for use in vivo. The invention is also directed to methods for forming coatings comprising or consisting of titanium phosphate and/or zirconium phosphate on the surface of a substrate.
Patent AU-2019235551-A1 (AU)
Title: On-demand artificial intelligence and roadway stewardship system
Inventor: RATTI JAYANT
IPC: G06K9/00
Filed: 2019-02-18
Abstract: The present disclosure relates to artificial intelligence based systems and method for determination of traffic violations. The present disclosure use deep convolutional neural networks and machine vision based algorithms to perform a task of detection and recognition to provide complete solution to safe, legal and comfortable parking, driving and riding for commuters on the roadways. Roadway stewardship systems, Parking management systems when made on-demand and crowdsourced, can play a very strong role in regulating driving conditions in cities and highways. By allowing the on-demand, crowdsourced, roadway stewardship system to be automated, through the use of Artificial Intelligence (AI) sub-systems, users can be trained to recognize and be educated as well in the laws & regulations around the use of roadways; can help the process through an interactive console / game-play, which can also be used for monetization for individuals to earn money for their contribution.
Patent AU-2019250911-A1 (AU)
Title: Method and system for making personalized nutritional and pharmaceutical formulations using additive manufacturing
Inventor: HUDSON JR EDISON THURMAN
IPC: A61K9/00
Filed: 2019-04-01
Abstract: The presently disclosed subject matter is directed to a system and method of preparing personalized nutritional and/or pharmaceutical formulations using additive manufacturing technology. Active pharmaceutical or dietary supplement ingredients are suspended in thixotropic stable carrier medias. The thixotropic suspensions are deposited onto a surface of a solid substrate, which can be a snack bar or small wafer used as a mechanical carrier. The disclosed system enables each additive active ingredient to be variably dosed based on a formula that is determined for each specific individual and manufactured on demand. Once the active ingredients are deposited on substrate, the entire assembly can be enrobed with one or more edible solid coatings to seal the active ingredients and provide taste-masking agent characteristics to the assembly.
Patent AU-2019251474-A1 (AU)
Title: Releasable palatal expanders
Inventor: KOPELMAN AVI
IPC: A61C7/10
Filed: 2019-04-10
Abstract: Releasable and removable palatal expander apparatuses (100) for expanding a patient's palate ("palatal expanders") and methods of using and making them. These releasable palatal expanders (100) are adapted for ease in removal by the patient or caregiver, and may include a breach region (167) configured to predictably bend or break when a pulling force is applied. The palatal expander apparatuses (100) described herein may include one or more locks for locking the palatal expander onto the patient's teeth. The lock(s) may be unlocked to release the palatal expander from the teeth. A lock may include a control for manually unlocking the lock. Unlocking the locks may allow the palatal expander to automatically disengage from the patient's teeth.
Patent AU-2019259998-A1 (AU)
Title: Pharmaceutical compositions for prevention and/or treatment of infections and antibacterial-induced dysfunctions
Inventor: TYPAS ATHANASIOS
IPC: A61K38/12
Filed: 2019-04-17
Abstract: The present invention relates to the field of therapeutics and, more in particular, to pharmaceutical compositions for the prevention and/or treatment of bacterial infections and antibacterial-induced dysfunctions. The compositions of the present invention demonstrate high species-specificity in inhibiting the growth of a small number of bacterial species, and most importantly are effective also against multi drug resistant (MDR) clinical isolate species. Interestingly, one of those combinations pairs a non- antibiotic drug, vanillin, with an antibiotic drug, spectinomycin, to demonstrate a surprisingly strong inhibitory effect on the growth of clinically relevant Gram-negative pathogenic and multi-drug resistant E. coli isolates. A second set of compounds combines the polymyxin colistin with loperamide, a rifamycin, or a macrolide. Importantly, this invention relates to combinations that enable narrow-spectrum antibacterial therapies, constituting a major effort of current and future drug development efforts in order to prevent major side effects of antibacterial strategies. This invention also relates to pharmaceutical combinations useful to prevent an adverse effect on the gut microbiome, induced by the use of antibacterial compounds.
Patent AU-2019261749-A1 (AU)
Title: Assembled energy dissipator with variable stiffness for lateral connection of shear walls
Inventor: ZHU LIMENG
IPC: E04B2/58
Filed: 2019-07-02
Abstract: The present invention relates to seismic resistances of buildings, and more particularly to an assembled energy dissipator with variable stiffness for lateral connection of shear walls, including an energy-dissipating zone, a stiffness enhancing zone and end plates for connecting shear walls. The shear walls are connected by the end plates via high-strength binding stay bolts. The stiffness enhancing zone includes a plurality of steel plates and buckling-restrained plates which are respectively arranged on two sides of adjacent steel plates and are connected to the steel plates via bolts. A gap is provided between the adjacent steel plates. The stiffness enhancing zone is provided with a threshold control device. The assembled energy dissipator realizes a reliable lateral bolt connection of shear wall components, and is easy to be assembled and disassembled. The present invention adopts a configuration that the steel plates of the energy-dissipating zone are arranged outside and the steel plates of the stiffness enhancing zone are arranged inside. Under a small or moderate earthquakes, the mild steel of the damper yields to dissipate energy while the steel plates in the enhancing zone are not required to work. When a strong or super strong earthquake occurs, the steel plates in the enhancing zone begins to work to enhance the structural performance. 11854774_1 (GHMatters) P112366.AU
Patent AU-2019262189-A1 (AU)
Title: Carotenoid compositions and uses thereof
Inventor: NIYIKIZA CLET
IPC: A61K31/01
Filed: 2019-05-03
Abstract: Provided herein are pharmaceutical compositions comprising carotenoids, including liposomes that encapsulate carotenoids including ionizable carotenoids such as trans-crocetin. The provided compositions have uses in treating diseases, disorders and conditions associated with, but not limited to, infection, endotoxemia, inflammation, sepsis, ischemia, hypoxia, shock, stroke, lung injury, wound healing, traumatic injury, reperfusion injury, cardiovascular disease, kidney disease, liver disease, inflammatory disease, metabolic disease, pulmonary disorders, blood related disorders and hyperproliferative diseases such as cancer. Methods of making, delivering, and using the pharmaceutical compositions are also provided.
Patent AU-2019263822-A1 (AU)
Title: Electric power generating system
Inventor: NAGASHIMA KAZUHIKO
IPC: F01K25/10
Filed: 2019-04-02
Abstract: Provided is an electric power generating system that has higher energy recovery efficiency than prior-art systems and can generate not only cold but also heat. The present invention provides an electric power generating system in which working fluid is circulated, while changing the state thereof, in a pressure-resistant sealed circuit system to convert external heat energy applied to the working fluid into kinetic energy and thus to generate motive power, and a power generator is driven by this motive power to generate electric power, wherein the pressure-resistant sealed circuit is formed of a main circuit and a sub circuit, the main circuit includes an evaporation chamber, a heat-insulating expansion chamber, a power generation chamber, a heating heat-exchange mechanism, and a liquefied-working-fluid reflux means, and the sub circuit includes a heat-medium diverting path, a liquefied-auxiliary-fluid supply path, a cooling facility, a second heated-fluid supply path, a heating facility, and a return compression means.