baber/WOPTO huggingface dataset:
Patent CS-195286-B2 (CS)
Title: Method of preparing cephalosporin compounds
Inventor: SPRY DOUGLAS O
IPC: C07D501/14
Filed: 1975-04-18
Abstract: 1505848 3,4 - Dicarboxycephalosporins ELI LILLY & CO 17 April 1975 [19 April 1974] 15803/75 Heading C2C The invention comprises 3,4 - dicarboxycephalosporins of the Formula I wherein X is azido, chlorine, bromine, C 2-5  alkoxycarbonyloxy, OR 3 , wherein R 3  is H, C 1-6  alkyl, C 3-6  cycloalkyl, C 2-6  haloalkyl, 2,2,2-trihaloethyl methoxybenzyl, nitrobenzyl, benzyl, diphenylmethyl, C 2-5  alkanoyloxymethyl, phenyl or pharmaceutically acceptable non- toxic cation, SR 4 , wherein R 4  is C 1-6  alkyl, C 3-6  cycloalkyl, phenyl, benzyl, 1-methyl-1H-tetrazol-5-yl or 1,3,4-thiadiazol-2-yl, or -N(R 5 )Q, wherein R 5  is H, C 1-4  alkyl, C 3-6  cycloalkyl, benzyl, phenyl, or tolyl and Q is H, C 1-6  alkyl, C 3-6  cycloalkyl, benzyl, C 1-7  alkoxy, hydroxy, amino, anilino, amidino or C 1-3  acylamino provided that when Q is amidino or C 1-3  acylamino, R 5  is H, or wherein R 5  and Q, together with the nitrogen atom to which they are attached form a 5- or 6-membered saturated heterocyclic ring; R is a free or esterified carboxy group, and when R is a free carboxy group pharmaceutically acceptable non-toxic salts of the acid represented thereby; R 1  is H or R<SP>1</SP>CO- wherein R<SP>1</SP> is C 1-7  alkyl, C 3-6  cycloalkyl, C 3-7  alkenyl, cyanomethyl, halomethyl or 4-protected amino-4-protected carboxybutyl; a group R<SP>11</SP> wherein R<SP>11</SP> is 1,4-cyclohexadienyl, phenyl optionally substituted by up to three halogen atoms or radicals selected from OH, NO 2 , CN, CF 3 , C 1-4  alkyl, C 1-4  alkoxy, CH 2 OH or protected aminomethyl; a group of the formula R<SP>11</SP>-(Y) m CH 2 , wherein Y is O or S and m is 0 or 1, a group of the formula R<SP>111</SP>-CH(W)-, where R<SP>111</SP> is R<SP>11</SP> or 2- or 3-thienyl and W is OH, protected hydroxy, COOH, protected carboxy, NH 2  or protected amino or a group of the formula R<SP>1111</SP>CH 2 , where R<SP>1111</SP> is 2- or 3- thionyl, 2- or 3-furyl, 2-thiazolyl, 5-tetrazolyl or 1-tetrazolyl; R 2  is H or OCH 3 ; q is 0 or 1; Z is -CH 2 -C(COX)= or -CH=C(COX)-, with the proviso that when q is 1 Z is and R 2  is H; and their preparation by known methods.  The following intermediates are also prepared: benzhydryl 7 - [(2 - thienyl)acetamido]-3-hydroxymethyl (or formyl)-2-cephem-4-carboxylate; methyl and benzhydryl 7-[(2-thienyl)- acetamido] - 3 - (1,3 - dioxolan - 2 - yl) - 2 - cephem - 4 - carboxylate; and 7 - [(2 - thienyl)- acetamido] - 3 - formyl - 2 - cephem - 4 - carboxylic acid and its methyl ester. Pharmaceutical compositions contain the above antibiotics in association with pharmaceutically acceptable carriers therefor.
Patent CS-221921-B2 (CS)
Title: Hydraulic drilling appliance
Inventor: KARRU ESA
IPC: E21B44/02
Filed: 1980-06-19
Abstract: A hydraulic drilling apparatus, especially a rock drill comprising a body, a cylinder in the body and a percussion piston reciprocating in the cylinder. A tool is connected to the body and a motor is provided for rotating the tool. A control valve is also provided for the percussion power. A control valve is also provided for regulating the motor speed. Both of these control valves are operated independently by one lever. A hydraulically operated flushing valve is also provided. A hydraulic pump and hydraulic channels coact to form a percussion circuit and a rotation circuit is parallelly coupled with the percussion circuit in relation to the hydraulic pump. A flushing valve circuit is controlled by the percussion circuit and a circuit for the free circulation of the hydraulic pump which is parallelly coupled with the percussion circuit in relation to the hydraulic pump. The circuits are connected to the hydraulic pump. The control valves are disposed in the body of the percussion apparatus with one of these valves being in the rotation circuit for controlling the flow rate which valve is a pressure-compensated flow control valve with a throttling control.
Patent CS-214724-B2 (CS)
Inventor: KANO SABURO
IPC: F27D13/00
Filed: 1973-11-09
Abstract: Zařízení ik předehřívání práškové suroviny
ve vznosu před výpalem, zejména pro výrobu
cementářského slínku, které sestává ze
dvou paralelních několikastupňových soustav
k předehřívání suroviny jednak kouřovými
plyny z rotační pece a jednak spalinami
z přídavného hořáku v kalcinační peci.
Obě soustavy jsou za předposledními předehřívacími
stupni spolu spojeny a posledními
stupni obou soustav, které jsou zapojeny do
série, prochází celý proud suroviny do rotační
pece.
Patent JP-H0350460-B2 (JP)
IPC: H04B3/14
Filed: 1985-01-21
Abstract: 1. An adjustable delay equaliser with a negligible (all-pass filter comprises of lattice network or structures derived therefrom) or finite but constant operating attenuation (Darlington equaliser) for the generation of delay curves in the form of an axially symmetrical parabola with a variable opening in accordance with the equation t(eta)=tf +-d.ëta-eta F**n (d variable), where the delay curves are governed by a parabola classification n which is independent of the adjustment and possibily is also non-integral, by a position of the parabola summit point (eta F , t F ) which is independent of the adjustement, and by a tangent dt/d eta at the summit point which is independent of the adjustement, and possibly where dt/d eta=0, with a delay-determining (lattice network) reactance (XK ), characterized in that the lattice network reactance (XK ) comprises the parallel arrangement of a control reactance (XS ) and a fixed reactante (XF ) where the control reactance (XS ) is formed by the parallel arrangement of a fixed component (XSF ), composed of an inductance or a capacitance or a parallel oscillating circuit, and a variable component (XSV ) composed of parallel-connected series oscillating circuits, and a variable component (XSV ) composed of parallel-connected series oscillating circuits, and where the resonance frequencies of one section of these series oscillating circuits occur at frequencies below the summit point frequency eta F and those of the other section occur at frequencies above the summit point frequency eta F , whereas the fixed reactance (XF ) comprises a series oscillating circuit with the resonance frequency eta F  or a section of a transmission line which is reactively connected at its input end and/or output end, in such manner that at the summit frequency eta F  a reactance zero point occurs at the input end.
Patent AU-646716-B2 (AU)
Title: A method of preparing purified alkanesulfonic acid
Inventor: HENDERSON PHYLLIS ANN
IPC: C07C303/02
Filed: 1992-01-23
Granted: 1994-03-03
Abstract: A process of preparing purified alkanesulfonic acid from crude aqueous alkanesulfonic acid containing oxidizable impurities wherein the crude material is treated with a sufficient amount of chlorine to convert the oxidizable impurities to alkanesulfonyl chloride and then hydrolyzing said alkanesulfonyl chloride to alkanesulfonic acid by heating.
Patent AU-714561-B2 (AU)
Title: Production of ammonium acrylate
Inventor: SYMES KENNETH CHARLES
IPC: C12P7/40
Filed: 1996-12-12
Granted: 2000-01-06
Abstract: A solution having a high concentration of ammonium (meth)acrylate and which is substantially free of (meth)acrylonitrile is made by enzymatic hydrolysis of (meth)acrylonitrile in the presence of water using an enzyme that has Km for (meth)acrylonitrile below 500 mum and Ki for ammonium (meth)acrylate about 100,000.
Patent AU-778149-B2 (AU)
Title: Agonists specific for the peripheral cannabinoid receptor
Inventor: FRIDE ESTER
IPC: C07C62/32
Filed: 2000-10-30
Granted: 2004-11-18
Abstract: The invention provides novel pharmaceutical compositions comprising as the active ingredient 4-phenyl pinene derivatives which are specific for the peripheral cannabinoid receptors. In particular, the compounds of the invention binds efficiently to CB2 but do not bind to CB1. The compounds show no activity in behavioral tests in mice which together have been shown to be specific for tetrahydrocannabinol (THC)- type activity in the central nervous system mediated by CB1 but reduce blood pressure, block intestinal motility, and elicit anti-inflammatory and peripheral analgetic activity. The invention also relates to methods of treating, preventing, or managing hypertension, inflammation, pain, gastrointestinal diseases, autoimmune diseases, and tumors with the compounds of the invention.
Patent AU-711030-B2 (AU)
Title: Device for manipulating compressed video sequences
Inventor: GANDINI MARCO
IPC: H04N7/50
Filed: 1997-02-13
Granted: 1999-10-07
Abstract: An integrated circuit for manipulating digitised video sequences is provided, for use in a system for transmission and reception of compressed video sequences to perform, possibly with the aid of an external memory, re-ordering, format conversion, prediction and motion compensation on the pictures in a sequence. The device (MSM) comprises means (MT1, MT2) for temporarily storing sequences to be manipulated and data read from the external memory; means (DIB) for decoding information about the manipulations to be performed; addressing means (ISS, CM, CME) for transferring the data between the device and the external memory; means (IU, RC) for configuring the device by means of a remote processing unit; means (IHV) for processing the data read from the external memory; means (SU) for arranging the output sequences in the format required by the function to be performed. A controller may control, supervise and set up the functions to be performed. <IMAGE>
Patent AU-665752-B2 (AU)
Title: Recombinant thrombin receptor and related pharmaceuticals
Inventor: COUGHLIN SHAUN R
IPC: A61P7/02
Filed: 1992-02-19
Granted: 1996-01-18
Abstract: The DNA encoding the cell surface receptor for thrombin has been cloned and sequenced. The availability of this DNA permits the recombinant production of thrombin receptor which can be produced at cell surfaces and is useful in assay systems both for the detection of thrombin and for the evaluation of candidate thrombin agonists. Further, the elucidation of the structure of the thrombin receptor permits the design of agonist and antagonist compounds which are useful diagnostically and therapeutically. The availability of the thrombin receptor also permits production of antibodies specifically immunoreactive with the receptor per se or with specific regions thereof which are also useful diagnostically or therapeutically.
Patent AU-594877-B2 (AU)
Title: Method of manufacturing fiber-reinforced articles of plastics material
Inventor: OVERATH FRIEDHELM
IPC: B29C53/76
Filed: 1988-04-28
Granted: 1990-03-15
Abstract: A method of manufacturing a fiber-reinforced shaped article of plastics material for pipeline systems. The article includes an inner casing of a thermoplastic material and an outer casing of a fiber winding impregnated with resin. The tape is wound onto the inner casing so that at least the entire surface thereof is covered. The article is then immersed in a resin bath while a negative pressure is maintained outside of and in the interior of the article. The resin bath is subsequently subjected to atmospheric pressure. The impregnated article is removed from the resin bath and the resin is hardened by ultraviolet light while the article is simultaneously rotated.
Patent AU-735517-B2 (AU)
Title: Method and apparatus for chemical synthesis
Inventor: PALMER DEREK ADEYEMI
IPC: C40B50/14
Filed: 1998-12-15
Granted: 2001-07-12
Abstract: An apparatus and its use for chemical synthesis is disclosed. In one embodiment, the apparatus comprises a solid support input and a plurality of reagent inputs, wherein each input is connectable to a main fluid pathway via a respective switchable valve. The apparatus further comprises a reaction chamber that is fluidly connectable to the main fluid pathway by a respective switchable valve downstream of the inputs, and that includes an outlet downstream of a barrier that prevents passage of solid support but allows passage of unbound molecules.
Patent AU-733942-B2 (AU)
Title: Process for the purification of an alkanolamine
Inventor: GRINSVEN PETRUS FRANCISCUS ANT
IPC: C07C215/08
Filed: 1998-10-26
Granted: 2001-05-31
Abstract: A process for the purification of an aqueous alkanolamine which process comprises subjecting the alkanolamine to distillation process carried out in one or more film-type evaporators and comprising at least two steps, wherein in the first step water is removed from the aqueous alkanolamine and in the second step the de-watered alkanolamine is further purified.
Patent AU-778962-B2 (AU)
Title: Process for the production of amorphous atorvastatin calcium
Inventor: KUMAR YATENDRA
IPC: C07D207/34
Filed: 2000-01-06
Granted: 2004-12-23
Abstract: A process for the preparation of amorphous atorvastatin calcium and hydrates thereof which comprises: (a) dissolving crystalline atorvastatin calcium in a non-hydroxylic solvent; (b) adding a non-polar hydrocarbon anti-solvent or adding the dissolved atorvastatin to the non-polar anti-solvent to precipitate out atorvastatin calcium; and (c) removing the solvent by filtration to afford amorphous atorvastatin calcium.
Patent AU-657782-B2 (AU)
Title: Shoe construction
Inventor: MANN ERNEST S
IPC: A43B17/02
Filed: 1992-04-15
Granted: 1995-03-23
Abstract: A shoe having an insole with a forepart of leather having the characteristics of upper leather and a back part of fiberboard. A sheet layer of foam material, such as microcellular polyurethane, is cemented to the lower surface of the forepart and a foam cushion, preferably molded of microcellular polyurethane, overlies the back part. The back part of the insole has an opening through it and the foam cushion has a central portion that projects downwardly through the opening thereby providing a thickened foam at the central portion to maximize cushioning at the area of the heel strike. The invention is incorporated in shoes of both the welt-type construction and the cement-type construction.
Patent AU-780397-B2 (AU)
Title: Hydrogel particle formulations
Inventor: BURKOTH TERRY LEE
IPC: A61K48/00
Filed: 2000-02-03
Granted: 2005-03-17
Abstract: New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also provided. In addition, methods for administering pharmacologically active agent to a subject are provided. These methods are useful for delivering drugs, biopharmaceuticals, vaccines and diagnostics agents.
Patent AU-561864-B2 (AU)
Title: Tunnelling machine with shield
Inventor: AKESAKA TOSHIO
IPC: E21D9/06
Filed: 1984-03-29
Granted: 1987-05-21
Abstract: for thrusting a shield for use in tunneling includes the steps of causing a rotary head (14), provided at the front portion of a shield body (12), an eccentric motion sothat earth, soil or sand covering the front of the shield is pressed away radially of the shield, and exerting a thrust on the shield body during the eccentric motion of said rotary head. Apparatus for carrying outthe method includes a driven crank shaft (22) or a driven eccentric straight shaft, a conical or frustoconical rotary head (14) supported rotatably by the crank or eccentric straight shaft, conveyor for discharging mined material backwardly, and hydraulic jacks for imparting a thrust to the shield bodv.
Patent AU-688100-B2 (AU)
Title: Novel rhodamine derivatives for photodynamic therapy of cancer and in vitro purging of the leukemias
Inventor: GABOURY LOUIS
IPC: A61K41/00
Filed: 1995-08-16
Granted: 1998-03-05
Abstract: The present invention relates to novel photoactivable rhodamine derivatives for enhancing high quantum-yield production and singlet oxygen generation upon irradiation with light while maintaining desirable differential retention of rhodamine between normal and cancer cells. Representative derivatives are 2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester hydrochloride; 2-(4, 5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid ethyl ester hydrochloride; 2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid octyl ester hydrochloride; 2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid n-butyl ester hydrochloride; 2-(6-ethyl amino-3-ethyl imino-3H-xanthen-9-yl)-benzoic acid n-butyl ester hydrochloride; and photoactivable derivatives thereof. These derivatives are utilized in an amount to achieve appropriate intracellular levels of the derivative when irradiation of a suitable wavelength and intensity is applied to photoactivate the derivative and thereby induce cell killing.
Patent AU-715157-B2 (AU)
Title: Flexible piston rod
Inventor: KLITGAARD PETER CHRISTIAN
IPC: A61M5/315
Filed: 1997-06-10
Granted: 2000-01-20
Abstract: A flexible piston rod for use in cylinder ampoules comprises a tape shaped body (1) which is along its length provided with supporters (2; 6; 16) projecting from at least one side of the tape. The tape (1) has a width and the supporters a length so that sides of the tape and the free ends of the supporters abuts the inner wall of the ampoule (3) in at least three positions along the inner perimeter of the ampoule (3) and not all the abutment points lies on the same half of the circular cross section but are typically displaced about 120° from each other. The piston rod is moved by a gear engaging a rack (12) on the tape either on the side not carrying supporters or at the edge of the tape on the side carrying supporters.
Patent AU-716428-B2 (AU)
Title: A fluid treatment system
Inventor: CHURCH GARRY
IPC: G01N27/60
Filed: 1995-10-13
Granted: 2000-02-24
Abstract: PCT No. PCT/GB95/02437 Sec. 371 Date Apr. 7, 1997 Sec. 102(e) Date Apr. 7, 1997 PCT Filed Oct. 13, 1995 PCT Pub. No. WO96/11883 PCT Pub. Date Apr. 25, 1996A system and method for treating a fluid flowing along a main fluid supply path in which a streaming current detector receives a sample flow of a main fluid supply following main dosing with a chemical under control of a streaming current detector output. A secondary chemical dosing is applied to the sample under the control of the streaming current detector output in a feedback loop.
Patent AU-711798-B2 (AU)
Title: Use of starch for transdermal applications
Inventor: WIJDEVEN GIJSBERTUS GERARDUS P
IPC: A61K9/20
Filed: 1995-09-20
Granted: 1999-10-21
Abstract: The invention relates to the use of substantially fully destructurized starch for transdermal applications in humans and animals, in particular the use of solid particles such as implants. The invention further relates to the implants manufactured of substantially fully destructurized starch, in addition to methods for manufacturing the implants.
Patent AU-774742-B2 (AU)
Title: Control system and method for wheelchair
Inventor: KAMEN DEAN L
IPC: G05B13/04
Filed: 2000-03-14
Granted: 2004-07-08
Abstract: Systems and methods for controlling a device are disclosed. In one embodiment, the systems and methods allow for the control of a human transport device such that the human transport device remains in an upright position regardless of the surface being traversed. The systems and methods may include a plurality of operational modes where each mode has different characteristics. Additionally, systems and method for locating a center of gravity of a device are disclosed.
Patent AU-728090-B2 (AU)
Title: Intermediates for the preparation of 2-imidazoline-5-ones
Inventor: BUFORN ALBERT
IPC: C07D277/36
Filed: 1997-07-17
Granted: 2001-01-04
Abstract: Novel 2-thio-thiazolidine-5-one compounds useful as intermediates for fungicidal 2-imidazoline-5-ones are disclosed.
Patent AU-756151-B2 (AU)
Title: Immortalised cell lines derived from normal human skin tissues
Inventor: BAUR MARKUS
IPC: C12N15/09
Filed: 1999-04-07
Granted: 2003-01-02
Abstract: An human keratinocyte cell line immortalized by means of at least one functional tumor gene of retroviral origin characterised in that it is (1) non-tumorigenic, (2) conserves the capacity for differentiation and for the expression of proteins and of enzymes expressed by normal differentiated keratinocytes even after an elevated number of passages in culture, and (3) forms a stratified and polarised epithelium having a stratum corneum ortho-keratinocyte, if cultivated in an organo-typical culture in a medium without serum and without a layer of nourishing cells. An improved process to immortalize human skin cells to obtain immortalized keratinocytes is characterised in that it comprises the following steps: (i) isolating a sample of human skin; (ii) preparing the sample of skin for in vitro culture; (iii) obtaining keratinocytes from this prepared sample of human skin and seeding in a growth medium without serum with said keratinocytes, on culture plates provided with a coating comprising fibronectin, collagen type I and SAB, which facilitate the fixation and the growth of cells; (iv) replacing the medium in a way sufficient to obtain an optimal confluent growth of cells in culture, continuously maintaining the coating of the plate; (v) transferring keratinocytes into a selection medium without serum on culture plates coated previously in a similar manner; (vi) infecting keratinocytes using functional tumor genes of at least two different retrovirus; (vii) transferring the resulting immortalized keratinocytes to a proliferation medium suitable for the proliferation of immortalised keratinocytes on culture plates coated in a similar way; (viii) transferring the resulting proliferated keratinocytes into a differentiation medium having a high content of calcium on culture boxes coated in a similar way. Use of keratinocytes for immunological, pharmacological, photo- and chemical-toxigological analyses of skin reaction and for expression of heterologous genes and for the construction of artificial skin.
Patent AU-668569-B2 (AU)
Title: Plastic closure with warranty element
Inventor: DUBACH WERNER FRITZ
IPC: B65D55/02
Filed: 1993-07-08
Granted: 1996-05-09
Abstract: A one-piece plastic closure for fastening on a container having a lower part with a top surface which forms a pouring opening, and a cap pivotably connected to the lower part by a hinge shaft. A security element is connected to the closure such that, during initial opening of the closure, the security element is transformed from a secured state to a visually recognizable state of use.
Patent AU-562124-B2 (AU)
Title: Dehydrogenation of butanes
Inventor: OLBRICH MICHAEL EUGENE
IPC: C07C11/09
Filed: 1985-06-06
Granted: 1987-05-28
Abstract: A process for dehydrogenation of a feedstock containing isobutane, n-butane, and butadiene using a steam active dehydrogenation catalyst which is (a) a calcined support of at least one aluminate spinel composition, (b) at least one Group VIII metal, (c) with or without at least one Group IA metal and (d) at least one tin group metal selected from among tin, germanium, and lead under dehydrogenation conditions to produce a product stream of isobutane, n-butane, butenes, isobutene, and butadiene with a separation of the product stream to provide a recycle feedstock composition containing isobutane, n-butane and butadiene which is recycled to the reaction zone along with fresh feedstock providing a combinped feedstock that has up to 20 mol percent n-butane and up to 5 mol percent butadiene. Optionally, repeating product separation and recycling of feedstock along with fresh feedstock without producing a buildup of by-product butadiene in the cycle.