baber/WOPTO huggingface dataset:
Patent CR-20190393-A (CR)
Inventor: ALBERS MICHAEL
IPC: C07D471/04
Filed: 2018-02-01
Abstract: La presente invención se refiere a compuestos que pueden actuar como moduladores del receptor de hidrocarburos de arilo (AhR) y, en particular, como antagonistas de AhR. La invención además se refiere al uso de los compuestos para el tratamiento y/o profilaxis de enfermedades y/o condiciones a través de la unión de dicho receptor de hidrocarburos de arilo por dichos compuestos.The present invention relates to compounds which can act as aryl hydrocarbon receptor (AhR) modulators and, in particular, as AhR antagonists. The invention further relates to the use of the compounds for the treatment and/or prophylaxis of diseases and/or conditions through binding of said aryl hydrocarbon receptor by said compounds.
Patent CR-20210545-A (CR)
Title: Solid forms of a glyt1 inhibitor
Inventor: GAO JOE JU
IPC: C07D413/04
Filed: 2020-04-30
Abstract: Disclosed are solid forms of an inhibitor of glycine transporter-1 (GlyT1). The invention also relates to methods of making these solid forms, pharmaceutical compositions comprising these solid forms, and their use for medical conditions responsive to treatment with an inhibitor of glycine transporter-1.
Patent EC-SP003432-A (EC)
Title: Nuevo metodo de tratamiento
Inventor: CONLEY CREIGHTON P
IPC: C07D205/00
Filed: 2000-04-27
Abstract: Infecciones bacterianas se pueden tratar empleando un alto régimen de dosis de amoxicilina y clavulanato potásico. Preferentemente, la dosis se proporciona mediante un comprimido con dos capas.
Patent EC-SP066757-A (EC)
Title: Composicion farmaceutica directamente comprimible para la administracion oral de 42-ester de rapamicina con acido 3-hidroxi-2-(hidroximetil)-2 metilpropionico
Inventor: ASHRAF MUHAMMAD
IPC: A61K31/4745
Filed: 2006-08-08
Abstract: Se describe CCI-779 micronizado; el 42-éster de rapamicina con ácido 3-hidroxi-2-(hidroxi-ilmetil)-2-metilpropiónico provee un método conveniente y efectivo para suministrar niveles terapéuticos de CCI-779 a un paciente.
Patent EC-SP088095-A (EC)
Title: Producto de tisú para baño enrollado para niños
Inventor: SHANNON THOMAS G
IPC: A47K10/38
Filed: 2008-01-10
Abstract: Esta generalmente descrito un producto de tisú enrollado que puede ayudar al progreso de un niño en el proceso de aprendizaje de uso del retrete. El producto de tisú enrollado puede tener un patrón, localizado sobre el tejido de tisú, de manera que el patrón ayuda al niño a determinar la cantidad apropiada de tisú para baño que puede ser usada. También algunas perforaciones en el tejido de tisú pueden ser más débiles que otras perforaciones para ayudar al niño a romper limpiamente la cantidad apropiada de tisú para baño del rollo. Algunas perforaciones en el tejido de tisú pueden tener claves visuales para indicar en donde esta localizada la perforación.
Patent FI-20002864-A (FI)
Inventor: PAASIO ARI
IPC: G06T1/40
Filed: 2000-12-28
Abstract: A processor, a circuit and a method for processing images in an analog parallel processor network. A processor comprises a plurality of circuits, a bias transistor and an output transistor. A circuit comprises a first transistor and a second transistor, which receive respective supply voltages and operate as current sources, providing an output voltage. A circuit further comprises a coefficient coupling, which receives the output voltage provided by the first transistor and the second transistor, providing a switching function for a circuit output current. A transistor in a coefficient coupling determines a mode of operation based on the output voltage, provided by the first transistor and the second transistor, and an input current. The circuit provides an output current of the circuit for further processing.
Patent FR-1208216-A (FR)
IPC: B29C65/20
Filed: 1957-11-14
Granted: 1960-02-22
Abstract: 846,955. Joining plastic piping &c. SVENSKA METALLVERKEN A.B. Nov. 13, 1957 [Nov. 14, 1956], No. 35415/57. Class 87(2). [Also in Group XXVIII] Plastic parts are joined by bringing their contacting surfaces to abut against heated metal moulding members and retaining them there until the plastic material is brought into a molten or melting condition when the parts are removed from the moulding members and assembled. The invention is described with respect to the joining of plastic piping, e.g. of polyethylene or polypropylene, one of the pipes 1 being formed with a preformed sleeve 3 the inner surface 4 of which is shaped to be either conical or cylindrical, the outer surface of the other pipe 2 being similarly shaped. To this end the apparatus of Fig. 1 is used, this comprising pairs of cup-like members 19, 20 located opposite each other on plates 14, 15 between which extend heat transferring plates 21. The plates 21 are heated by the flame from burner 7 and transmit the heat by conduction and radiation to the members 19, 20. The pipes are introduced to the apparatus in the direction of arrows A, B, the sleeve 3 surrounding member 20 and the pipe 2 entering member 19, and when their surfaces are sufficiently molten, the pipes are assembled as shown at the top of Fig. 1. The melting should be to a depth of between zero and 35%, preferably 10 to 15%, of the total thickness of the plastic. In a modified form of apparatus, a pressure vessel containing heat transfer fluid such as water, oil, salt solution or the like may be used in place of plates 14, 15.
Patent FR-1603213-A (FR)
Title: Fuel cell supplied by gases at atmospheric pressure
IPC: H01M8/08
Filed: 1968-10-10
Granted: 1971-03-22
Abstract: The need to pressurise the gas supply lines of fuel cells is avoided by operating the cell below atmospheric pressure thus preventing the flow of electrolyte through the porous electrodes. The reduction in pressure is obtained by maintaining the cell above the electrolyte reservoir, the difference in pressure being determined by the height difference and the electrolyte density. A further pressure reduction (up to 500g/cm2) is obtained by placing the circulating pump in the exhaust line with a regulating valve in the inlet line. Entrained gas bubbles are removed by a degassing pump in the exhaust line.
Patent GB-1000009-A (GB)
Abstract: 1,000,009. Centrifugal, centripetal screw pumps, &c. SIGMUND PUMPS Ltd. Nov. 8, 1963 [Nov. 30, 1962], No. 45518/62. Heading F1C. [Also in Division G3] A water circulating pump unitary with a mixer valve for a heating system comprises an electric motor 11 having a shaft mounted centrifugal impeller 18 in a chamber 14 separated by a plate 17 from mixing chambers 15, 16, chamber 15 communicating with a port 19 and chamber 16 with ports 20-22 and with pump chamber 14 by an annular aperture 40. An aperture 25 communicates directly with the eye of the impeller and an aperture 26 is selectively covered by a shutter 27 positioned by a manually operated arm 30 to vary the pump output. The chamber 16 has two projections 34, 35 which engage a rotatable obturator 38 positionable also intermediately by a linkage motivated by a bellows expanded by a fluid heated electrically. In operation water is drawn from a heating system through port 19 to the eye of the impeller and discharged at the periphery through port 20 to a boiler, the heated water passing directly from port 22 to port 21. When the required temperature is reached a thermostat closes energizing the bellows heater thus moving the obturator, restricting the flow of water from the boiler and allowing water from aperture 40 to flow to port 21.
Patent GB-1034010-A (GB)
IPC: H05B6/02
Abstract: 1,034,010. Charging induction furnaces. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. Dec. 10, 1964 [Dec. 13, 1963], No. 50301/64. Heading F4B. An induction heating oven 1 has charging and discharging means comprising a driving member or piston 16 whose head 4 supports the stacked objects 3 to be heat treated in the passageway of the induction oven. The piston 16 and the stacked objects thereon are moved upwardly through the oven until contact carrier 17, whose head 7 abuts the leading face of the first object 6, abuts contact switch 7<SP>1</SP> whereupon the piston 16 is stopped, clamping plates 9 are operated to hold the second object 8 and a plate 10 pushes away the leading object 6 whose heating has been completed. The plates 9 are then retracted and the piston 16 and stacked objects 3 lowered until trip member 11, mounted by collar 20 about piston 16 to permit the latter to slide therethrough during its upward movement when the trip member 11 has abutted stop 12, abuts contact switch 13. This operates clamping plates 14 to grip the lowermost object 5 whilst another object to be heat-treated is inserted between object 5 and piston head 4. The cycle is then repeated. Contact 13 is positionally adjustable so that objects of various lengths may be treated in the induction oven, which may be modified to operate horizontally.
Patent GB-1050098-A (GB)
IPC: H01T1/14
Abstract: 1,050,098. Surge diverters. LICENTIA PATENT - VERWALTUNGS - G.m.b.H. Oct. 9, 1963 [Oct. 9, 1962; March 20, 1963]. No. 39801/63. Heading H2H. To protect a surge diverter from excessive mechanical and electrical stress during prolonged arcing, a metal conductor 3 is connected to the high voltage terminal 2 and arranged so that its other end terminates in the region of the stream 7 of ionized gas which emerges from the diverter housing 4 when the excess-pressure diaphragm in funnel 9 ruptures. This condition causes an arc to form between the end of conductor 7 and the earth terminal pin 6, thus by-passing the diverter. In another embodiment, Fig. 2 (not shown), in which the diverter is spaced from a wall by a horizontal support bracket and has its exhaust funnel located at the upper end and directed towards the wall, the conductor 3 comprises an earth strip running vertically up the wall and connected to the lower terminal of the diverter. The Specification envisages the application of the invention to other electrical equipment such as transformers, circuit breakers and bushings.
Patent GB-1050714-A (GB)
IPC: B42F13/00
Abstract: 1,050,714. Filing papers. W. LENNARTZ. Aug. 6, 1964 [Aug. 8, 1963 (2)], No. 31968/64. Heading B6E. A loose-leaf binder comprises front and back covers 1, 1<SP>1</SP>, connected to a spine 6, filing rings 3 for the papers &c. rigidly secured to the cover 1<SP>1</SP> or the spine 6, transverse slots 2 in the cover 1 so that the rings 3 can enter the slots when the binder is closed, and rivet-like members arranged in the cover 1 so that their head parts 4 project into the slots 2 to serve as catch devices to retain temporarily the posts 3 in the slots. In a modification, the opposite head portion of each rivet may also project into the slot to form a rest for the ring. In another construction the rivet heads are leaf springs which project into the slots to retain the filing posts 3.
Patent GB-1082318-A (GB)
Abstract: 1,082,318. Removing metal by cathodic etching. WESTERN ELECTRIC CO. Inc. Oct. 14, 1964 [Dec. 17, 1963; Feb. 25, 1964; Aug. 7, 1964], No. 8613/67. Divided out of 1,082,317. Heading B3V. [Also in Division H1] To remove material from a differentially coated body 219, it is mounted on but insulated from a cathode 213 and the material removed by " reverse sputtering," a suitable potential being set up between the cathode and an anode 212. The atmosphere in the sputtering chamber is a low-pressure gas, specifically argon at about 10 microns, and the effect of the potential between anode and cathode is to set up an annular glow discharge region 231 surrounding the workpiece. Ions in the atmosphere, following paths such as 232 enter the discharge region where they are both accelerated and deflected, and emerge to strike the workpiece substantially perpendicular to its surface. The surface of the workpiece is differentially coated, some areas being coated either more thickly or with material of lower sputtering efficiency than the remaining areas. Such areas serve as masks for the remaining areas, the latter being removed by ionic bombardment along parallel-sided paths perpendicular to the workpiece surface and bounded by the edges of the masking areas. The process is preferred to conventional reverse sputtering for such workpieces as oxidecoated semi-conductor bodies, as the insulation from the cathode 213 prevents the development of deleterious potentials across the semiconductor and oxide. Fig. 2 (not shown), depicts such a semi-conductor workpiece, which consists of an oxide-coated semi-conductor body containing a plurality of devices such as transistors. Each such transistor (Fig. 4, not shown) has its base and emitter regions contacted by sequentially deposited layers of platinum, titanium and platinum, initial deposition being through apertures in an oxide layer on the device surface and subsequent deposition extending over the oxide. Masking strips of thin aluminium or thick gold are then laid on the platinum to define contact areas. The sputtering removes excess platinum and titanium not covered by the aluminium or gold.
Patent GB-1225457-A (GB)
IPC: G04C3/06
Filed: 1969-11-21
Abstract: 1,225,457. Electric clocks. KIENZLE UHRENFABRIKEN G.m.b.H. Nov. 21, 1969 [Nov. 23, 1968], No. 57044/69. Heading G3T. An electro-mechanical oscillatory system particularly for a timepiece comprises an oscillatory member e.g. a balance, restrained by a spring 8, a permanent magnet or permanent magnets, e.g. magnets 1 and 9, co-operating with control and drive coils 2, 10 in an electronic circuit, (not shown) and means for adjusting the position of the control coil 2 relatively to the magnet 1 with which it co-operates along lines of magnetic flux from the latter. The control coil 2 is carried by a frame 3 adjustable about a pivot 11 by rotation of a screw 4 to which is secured an accentric pin 5 mounted in fixed bearings.
Patent GB-1228517-A (GB)
IPC: C08K5/521
Filed: 1969-06-24
Abstract: 1,228,517. Flame-retarded polymer compositions. AMERICAN CYANAMID CO. 24 June, 1969 [1 July, 1968 (3)], No. 31933/69. Headings C3P and C3R. A flame-retardant composition for thermoplastic polymers comprises the combination of the following chlorine containing compounds wherein R and R<SP>1</SP> represent, when taken together, an oxygen atom, or, individually, a hydroxyl radical, an alkoxy radical or 1-8 carbon atoms or a haloalkoxy radical of 1-4 carbon atoms, with: (A) a phosphinic acid having the formula wherein R<SP>2</SP> represents an alkyl radical of 1-6 carbon atoms, a cyano-, hydroxy- or carboxysubstituted alkyl radical of 1-5 carbon atoms, an aryl radical of 6-10 carbon atoms or an α-hydroxybenzyl radical, and R<SP>3</SP> is hydrogen or R<SP>2</SP>; (B) a trisubstituted phosphine having the formula wherein R<SP>4</SP>, R<SP>5</SP> and R<SP>6</SP> represent alkyl radicals of 1-6 carbon atoms, cyano- or hydroxysubstituted alkyl radicals of 1-6 carbon atoms (no more than one alkyl substituent or cyano- or hydroxy-substituted alkyl substituent being present in the phosphine if the number of carbon atoms in the alkyl group is less than six), or aryl radicals of 6-10 carbon atoms; or (C) a phosphine oxide having the formula wherein R<SP>7</SP>, R<SP>8</SP> and R<SP>9</SP> represent cyano-alkyl radicals of 1-4 carbon atoms, carbamoylethyl radicals, N or N,N<SP>1</SP> - alkyl - substituted carbamoylethyl radicals or aryl radicals of 6-10 carbon atoms. The term "aryl radical" includes lower alkyl and halogen ring-substituted phenyl compounds. Each of the two components of the combination is incorporated into the polymeric material in concentrations ranging from 1.0% to 20% by weight, with preferred ratios for the two components of from 3: 1 to 1: 3. They may be added to the polymer as such or in combination, by blending, milling, or extrusion, or by moulding the components and polymer simultaneously. Alternatively, they may be added during the monomer polymerization. Plasticizers, dyes, pigments, heat and light stabilizers, antioxidants, antistatic agents and photochromic materials may be included in the flame-retarded polymer compositions. Many polymeric materials are mentioned, of which the following feature in the examples: polypropylene, polystyrene, butadiene-styrene copolymer, ABS type resin, poly (methylmethacrylate), and nylon (adipic acid-hexamethylenediamine reaction product).
Patent GB-1229749-A (GB)
IPC: B01J21/06
Filed: 1969-03-18
Abstract: 1,229,749. Refining catalysts. MOBIL OIL CORP. 18 March, 1969 [4 April, 1968], No. 14183/69. Heading B1E. [Also in Division C5] Refining catalysts comprise (A) a base containing, on a dry basis, (1) from 20-95% of an amorphous synthetic inorganic oxide gel consisting of SiO 2  gel or SiO 2 -metal oxide gel wherein the metal is Mg or a Group IIIA or IVb metal and (2) from 5-80% of a solid inorganic particulate material characterised in that when heated at 1200‹F for one hour it has a smaller degree of shrinkage than similarly heated component (1) and (B) a hydrogenation component intimately admixed with the base and being a metal, metal oxide or metal sulphide the metal being of Groups VIB, VIIB or VIII and being present from 0.1-50%. Specified solid inorganic particulate materials are clay, Al 2 O 3 , ZrO 2 , TiO 2 , SiO 2 , SiO 2 -ZrO 2 , SiO 2 -Al 2 O 3 , SiO 2 -TiO 2  and SiO 2 - MgO. The hydrogenation component may be oxides or sulphides of Co-Mo, Ni-W or Pt metal. Examples provide preparative details and physical properties of. products.
Patent GB-1230213-A (GB)
IPC: B23B31/02
Filed: 1968-09-13
Abstract: 1,230,213. Chucks; cutter arbors. E. JAHRL. 13 Sept., 1968 [15 Sept., 1967], No. 43711/68. Headings B3B and B3K. A chuck for gripping a tool holder 9 comprises at least two sets of balls 11 and 12 held in engagement with recesses or grooves in the holder 9 by a spring-biased outer sleeve 3, the set of balls 12 engaging rigidly in recesses to lock the holder against relative rotation whilst the set of balls 11 act on the slope of a groove 14, or equivalent recesses, to resiliently urge the holder 9 into the chuck. For additional locking the holder may be provided with screw-threads to screw into the end of the outer sleeve 3 (Figs. 2 and 3, not shown). A locking device may be provided to lock the sleeve 3 in its locked position and comprises a nut and ball-race co-operating with a groove in the chuck body (Figs. 7-9, not shown).
Patent GB-1231878-A (GB)
IPC: C08G63/82
Filed: 1968-11-21
Abstract: 1,231,878. Catalysed production of aromatic halogenated polyesters. DYNAMIT NOBEL A.G. 21 Nov., 1968 [22 Nov., 1967], No. 55296/68. Headings C3R and C3T. In the production of polyesters from a halogenated dihydric phenol and an acid dihalide of a dicarboxylic acid, there is used as a catalyst, either a a compound of the general formula where X is phosphorus, arsenic or antimony, and R<SP>1</SP>, R<SP>2</SP> and R<SP>3</SP>, which may be the same or different, are hydrogen or a fluorine free alkyl, cycloalkyl or aryl group, or a quaternary derivative of such a compound of formula where R<SP>1</SP> ,  R<SP>2</SP> and R<SP>3</SP> are as above and R<SP>4</SP> is selected from the same groups as R<SP>1</SP>, X is as above, and Y is a hydroxide, halide or acylate ion. The diacid halides specified are those of terephthalic acid, isophthalic acid and sebacic acid and mixtures thereof. Dihydric, halogenated phenols specified are 2,2-bis(3,5-dichloro - 4 - hydroxyphenyl) - propane, the corresponding bromine compound and mixtures thereof. The process may be carried out in the melt, in solution or with the components dispersed in a non-solvent. Some of the dicarboxylic acid dichloride may be replaced by a small amount of a dihalide of a tri- or pentavalent phosphorus acid, e.g. phenyl phosphonic acid dichloride or of a dihalide of a silane, e.g. diphenyldichlorosilane. In Examples 10 to 13 ployesters are made from chlorinated bis-phenol A, terephthalic acid chloride and isophthalic acid chloride, and also small amounts, 1%, 2%, 5% and 10% by weight respectively, of diphenyl dichlorosilane, using one of the catalysts above.
Patent GB-1232055-A (GB)
IPC: B32B15/00
Filed: 1968-10-03
Abstract: 1,232,055. Moulding metal-reinforced resin composites. NATIONAL RESEARCH DEVELOPMENT CORP. 1 Oct., 1969 [3 Oct., 1968], No. 46904/68. Heading B5A. [Also in Division B3] A composite article having a hollow sheath of metal housing a fibre reinforced resin core is made by impregnating a fibrous material e.g. a tow with resin and partially curing the resin. The resin fibre mix is then threaded into a bore 15 within a block of extrudable metal 16 and the metal and mix hydrostatically extruded through a die 12 using liquid resin 17 as the hydrostatic fluid. The resin is then fully cured. The fibres may be carbon, the metal aluminium and the resin epoxy, polyester, polyimide or furane. A compressor blade may be formed from the composite extrudate. One end of the rod is closed with a cap and is placed between dies 21a and 21b and heated. The extrudate is moved until the heated portion is between dies 22a, 22b and these are pivoted about points 26, 27 to compress the extrudate so that it takes up the shape of the die cavity. Excess material forces dies 23a, 23b apart against pressure supplied from source 28. The pressed article is then moved between dies 24a, 24b and subsequent dies if necessary and the resin is cured. The process is generally performed on a long strip of the composite, the end also being sealed with a cap.
Patent GB-1233384-A (GB)
IPC: G01S1/54
Filed: 1968-06-11
Abstract: 1,233,384. Electromagnetic wave position finding. J. M. LAPEYRE. 11 June, 1968, No. 27749/68. Heading H4D. The distance R of a transmitter 20, Fig. 1, from a receiver 44 is determined by measuring the time interval t, Fig. 2, A, between reception of the parallel edges (separation d) of electromagnetic beams 26, 28, the beams being rotated together at constant angular velocity a; distance R equals d/ta. Transmitter.-A maser 24 affording continuous or pulse waves is utilized, the wavelength being in the range from microwaves to ultraviolet. In the embodiment a beam splitter 32 (which may be a knife-edge prism and two adjustable plane mirrors) provides the beams 26, 28; a turn-table 35 affords continuous beam rotation. A transmitter 37 produces an omnidirectional pulsed radiation on preferably a different wavelength when edge 34 coincides with a reference direction 38 (e.g. controlled by a photo-cell) for azimuth determination. Receiver.-The output of photo-multiplier 46, Fig. 2, A, is shaped, Fig. 2, B; the outputs of units 50, 52, 54 and 56 are shown on Fig. 2, C, D, E, F and G. AND gate 58 output, Fig. 2, H, is substantially of duration t and pulses from clock 62 are counted during that period. The counter is re-set by a pulse, Fig. 2, J, from unit 65. Azimuth determination utilizes the measurement, by counter 74, of the interval between the receipt of a pulse from transmitter 37 and the edge 34 of beam 28; waveform, Fig. 2, G, from bi-stable 56 is fed via differentiator and separator 76 as one input to bi-stable 68. Devices 64, 74 may be five-decade decimal counters with gas-filled tubes for display.
Patent GB-1233980-A (GB)
IPC: H03G7/06
Filed: 1969-06-26
Abstract: 1,233,980. Variable impedance circuit. SIEMENS A.G. 26 June, 1969 [27 June, 1968], No. 32254/69. Heading H4R. In a variable impedance circuit, Fig. 1, suitable for use in a compander, the impedance presented by a tertiary winding L3 to an external circuit is controlled by varying the base bias of a transistor T1 connected, in series with a reversed biased Zener diode Z, between the primary L1 and secondary L2 windings of the transformer. The linearity of such a circuit can be improved by the arrangement according to the invention, Fig. 2, in which a second transistor T2, complementary to T1, is connected in series with further primary and secondary windings L1<SP>1 </SP>and L2<SP>1</SP> and fed with the voltage developed across the resistor R2 in the first transistor circuit so as to carry a current similar, but of opposite phase, to that carried by transistor T1. The diode D provides compensation for the threshold voltage of the transistor T2.