baber/WOPTO huggingface dataset:
Patent CA-2205085-C (CA)
Inventor: TANZI RUDOLPH E
IPC: C12N5/071
Filed: 1994-10-19
Granted: 2008-12-02
Abstract: The invention relates to rapid methods for determining formation of A.beta.  amyloid and screening compounds which inhibit formation of A.beta. amyloid in vitro, as well as kits for carrying out the presesnt methods. Such an agent used in vivo may prevent, ameliorate or reverse the symptoms of Alzheimer's disease and A.beta. amyloidotic disorders related to Alzheimer's disease, Down's syndrome, and Guamanian amyotrophic lateral sclerosis/Parkinson's dementia complex. The process described in this invention involves the rapid induction of A.beta.  amyloid by a heavy metal cation capable of binding to a polypeptide comprising at least amino acids 6 to 28 of A.beta., such as zinc to form amyloid and determination of formation of tinctorial A amyloid. Moreover, a method of determining effectiveness of a candidate anti-amyloidotic agent for prevention or treatment A amyloidosis is described which uses cells cultures which express at least a human A.beta. peptide.
Patent CA-2209531-C (CA)
Inventor: HATTORI KOJI
IPC: H01M10/052
Filed: 1997-07-02
Granted: 2002-05-21
Abstract: The invention provides a lithium secondary battery, comprising a cathode (3) having a spinel-structured lithium-manganese complex oxide as the active material, which is characterized in that the particles of said spinel- structured lithium-manganese complex oxide are hollow, spherical secondary particles by sintering of primary particles, and said secondary particles have a mean particle size of from 1 to 5 micrometer and a specific surface area of from 2 to 10 m2/g. The lithium secondary battery has a high capacity and excellent charge- discharge cycle characteristics.
Patent CA-2210437-C (CA)
Inventor: LE TUAN VINH
IPC: B65B51/06
Filed: 1997-07-15
Granted: 2006-02-14
Abstract: A box or carton sealer is disclosed having a frame with a conveyor for moving boxes therethrough. First and second longitudinal, laterally spaced-apart, independent gravity operated centering bars move inwardly and outwardly to center the boxes in the sealer. The centering force produced by the centering bars is proportional to the distance the box is off center in the sealer. A shiftable weight assists the respective centering bars to move laterally as required. A floating head has an inclined entry ramp for riding up over the box and lifting the floating head to a desired height as the box passes thereunder. The floating head has a sealing device for attaching the box flaps at whatever height the flaps happen to be at under the floating head.
Patent CA-2210990-C (CA)
Inventor: PFLAUM ZLATKO
IPC: C07K1/14
Filed: 1996-02-06
Granted: 2001-07-03
Abstract: The present invention discloses a new process for the purification of vancomycin hydrochloride by combining preparative chromatography on a silica gel column  and the precipitation with ethanol from a salt-water-ethanolic solution without intermediary filtering, whereby the chromatographic purity of the product is  improved. The chromatography is carried out on a column containing a silica gel stationary phase and an alkaline-water-ethanolic mobile phase at defined pH, mobile pha se flow and temperature as well as the amount and concentration of vancomycin hydrochloride. The process is distinguished by the yield and chromatographic  purity of the obtained product of about 93% area. Vancomycin hydrochloride purified according to the present invention is usef ul for peroral as well as parenteral administration since the portion of impurities  it contains is for one third smaller than in hitherto available products.
Patent CA-2211477-C (CA)
Title: Voltage controlled attenuator
Inventor: CUGALJ DARKO
IPC: G02B6/26
Filed: 1997-07-24
Granted: 2003-03-25
Abstract: A voltage controlled attenuator for an optical telecommunication system comprises an optical attenuator placed between an input and an output lens f or obstructing the path of an incoming light beam. The attenuator has variable attenuation (reflection, absorption, etc.) which is controlled for maintaining a preset power of the outgoing light beam. To this end, a fraction of the outgoing signal is diver ted to an output detector by reflecting off an end face of a lens, and processed for o btaining a control signal representative of the output power. The control signal actuat es a dc motor which displaces the attenuator to a position corresponding to a preset outpu t power.
Patent CA-2217737-C (CA)
Title: Thf-containing sulfonamide inhibitors of aspartyl protease
Inventor: TUNG ROGER D
IPC: C07K5/078
Filed: 1996-04-18
Granted: 2009-04-07
Abstract: The present invention relates to a class of THF-containing sulfonamides which are aspartyl protease inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention.
Patent CA-2218201-C (CA)
Inventor: MESCHENMOSER ANDREAS
IPC: D21F3/04
Filed: 1997-10-14
Granted: 2006-12-19
Abstract: Press arrangement for a machine for treating a fibrous pulp sheet. The press arrangement includes a shoe press roll having a flexible press sleeve, a mating roll having a mating roll axis, and a press nip extended in a run direction of the fibrous pulp sheet and formed between the shoe press roll and the mating roll. The press arrangement includes a non-rotating carrier substantially extending across a machine width inside the flexible press sleeve, a press unit including at least one press shoe supported on the non-rotating carrier via at least one associated force element. The press unit exerts a force against the flexible press roll sleeve. The flexible press sleeve is arranged to circulate around the non-rotating carrier and to be guided around the at least one press shoe in a press nip area. A portion of the flexible press sleeve, located outside of the press nip area, circulates in a substantially circular-cylindrical path around a sleeve axis. A center plane of a resulting force exerted by the press unit is positionally offset a distance in the run direction from a plane including the mating roll axis and the sleeve axis, and the press shoe is positioned substantially symmetrical to the plane including the mating roll axis and the sleeve axis.
Patent CA-2218838-C (CA)
Title: Aqueous alkaline earth nitrate fertilizer composition and combustion process for making the same
Inventor: BABU MANYAM
IPC: B01D53/60
Filed: 1997-10-22
Granted: 2001-07-17
Abstract: A fertilizer composition containing an alkaline earth nitrate, such as calcium nitrate or magnesium nitrate is produced by the scrubbing of hot combustion gases to remove sulfur dioxide and nitrogen oxides from the gas.  After removal of sulfur dioxide from a gas stream,  a humidified gas stream containing NOx is treated to convert the NOx to nitric acid, and the nitric acid-containing humidified gas stream is contacted with an alkaline earth compound which reacts with nitric acid to form an alkaline earth nitrate in an aqueous effluent, which effluent comprises a fertilizer composition.
Patent CA-2225488-C (CA)
Inventor: ANDERSSON HANS
IPC: E06B9/40
Filed: 1996-06-18
Granted: 2006-01-31
Abstract: Store roulant doté d'un dispositif de fermeture (1) conçu pour être logé dans un étui ou un organe similaire lorsque le store est en position ouverte et se dérouler lorsque le store est en position fermé. Le dispositif possède un bord supérieur conçu pour être fixé à l'étui. Les bords latéraux (4, 5) du dispositif se déploient à partir de l'étui pour se terminer par un bord inférieur (7). Le store est pourvu de points de verrouillage, tels que des orifices (6, 8) pratiqués le long des bords latéraux et également, de préférence, le long du bord inférieur. Le long des bords munis de points de verrouillage sont montés des organes de verrouillage de forme allongée (10-12) comportant plusieurs éléments d'arrêt (19) pouvant être actionnés entre une position d'ouverture où les éléments d'arrêt se trouvent hors des points de verrouillage et une position de fermeture où les éléments d'arrêt (19) sont engagés dans les points de verrouillage (6, 8).
Patent CA-2228683-C (CA)
Inventor: XU JINGMING
IPC: H01S5/0625
Filed: 1998-02-20
Granted: 2002-05-14
Abstract: A superimposed grating tunable WDM semiconductor laser is provided comprising a grating structure is a binary superimposed grating comprising a plurality of segments of equal dimension, s, each segment having one of two values of refractive index, whereby the grating structure is provided by a binary modulation of the refractive index modulation of segments s along the length of the grating.      Thus, for a superimposed grating structure for an optoelectronic device for providing a spectrum comprising j reflection peaks at wavelengths .lambda. j, the grating comprising a binary superimposed grating (BSG) having a sequence of a plurality of segments of equal size s, each segment of the sequence having a refractive index of one of two values wherein the effective waveguide index of the ith segment n~(.lambda.) is allowed to be changed by .DELTA.n~(m-1/2) with m=1 or m=0:       where i=1,2,3... is the segment number, for digital position i~s, n o(.lambda.) is a waveguide effective index, including both waveguide and material dispersion, and the function f(x) is a weighted sum of sinusoidal functions of desirable period A j f(x)=~(a j sin(2.pi.x/~ j)) and, periods ~ j relate to the spectral positions of reflection peaks .lambda.  j through the waveguide index n o(.lambda.) ~ j = .lambda. j/2n o(.lambda. j) Thus each grating is defined in a truly binary fashion as a digitized binary representation of elements providing a sum of component functions. The structure is readily fabricated by electron beam lithography at normal resolution. The ease of fabrication makes this structure desirable for front and back reflectors for tunable WDM lasers for applications such as tunable lasers for telecommunications applications and provides for an extended tuning range with excellent performance characteristics.
Patent CA-2229496-C (CA)
Title: Method and equipment for mixing hard granules for tyre treads etc.
Inventor: JONSSON OLAFUR
IPC: B29C48/07
Filed: 1996-08-15
Granted: 2007-01-23
Abstract: The invention concerns a method and equipment for mixing hard granules into tyre tread bodies and furthermore into sundry rubber strips and tread stock, whereby rubber stock (5) is extruded (2) into tread bands (6) of a suitable shape which are rolled under control, in a suitable thickness and number of layers, in a circular process over a pre- treated tyre (9, 17) or other material (object) which is subsequently patterned and vulcanised. A distinctive feature of the invention is that the hard granules are distributed according to a predetermined configuration onto at least part of the surface of the extruded rubber tread band (6) before the next layer is rolled in a circular process onto the pre-treated tyre (9, 17), using dedicated equipment (1) so that the granules will be mixed into the patterned wearing surface of the tyre after profiling and vulcanisation.
Patent CA-2232835-C (CA)
Inventor: CHUANG LOCUS YAW-JEN
IPC: A23L27/30
Filed: 1998-03-23
Granted: 2004-09-28
Abstract: As aspartame-sweetened, acidic beverage mix is formulated wherein at least 20% of the aspartame is in bulk (i.e., needle-shaped crystalline particles) form and least 35% of the aspartame is coated onto acid particles.      This invention is well suited for powdered, sugar-free, ice tea mixes, particularly fruit-flavored mixes.
Patent CA-2236714-C (CA)
Inventor: KUPERSMIT CARL
IPC: G08G1/054
Filed: 1996-10-31
Granted: 2005-09-27
Abstract: L'invention concerne un procédé permettant de déterminer la vitesse d'un véhicule au moyen d'une caméra (10). Le procédé selon l'invention permet de corriger automatiquement les imprécisions de la détermination de la vitesse apparente dues à la position de la caméra (10) par rapport au véhicule. L'invention concerne également un procédé permettant d'étalonner une caméra (10) pour corriger les imprécisions dues à la position de ladite caméra (10).
Patent CA-2250789-C (CA)
Title: Packet telephone system
Inventor: FRASER ALEXANDER GIBSON
IPC: H04L12/56
Filed: 1997-03-20
Granted: 2004-08-10
Abstract: A packet telephone system which employs a packet network that provides virtual circuits. The packet telephone system employs short packets containing compressed speech. The use of the short packets makes possible compression and decompression times and bounded delays in the virtual circuits which are together short enough to permit toll-quality telephone service. The packet telephone system employs an intelligent network interface unit to interface between the packet network and standard telephone devices. The network interface unit does the speech compression and decompression and also responds to control packets from the packet network. Consequently, many telephone system features can be implemented in the network interface unit instead of in the switches. The network interface unit may also be used to provide data connections to devices attached to it. The combination of virtual circuits, with bounded delays, short packets, rapid compression and decompression, and intelligent network interface units makes it possible to build a telephone system with fewer and cheaper switches and fewer links for a given volume of traffic than heretofore possible and also permits substantial savings in provisioning and maintaining the system.
Patent CA-2255732-C (CA)
Inventor: HERNANDEZ-LOPEZ ARTURO
IPC: H05B41/288
Filed: 1997-03-17
Granted: 2004-10-19
Abstract: A high-efficiency self-regulated electronic ballast with a single characteristic curve for operating high-pressure sodium vapor lamps by means of an AC-to-DC converter circuit, a power factor correcting regulator circuit for reducing harmonic distortion, a high-frequency DC-to-AC converter circuit, a reducing autotransformer circuit with a current limiting inductor and an igniter, and a light-controlled switching circuit. The ballast is characterized in that it supplies a controlled high-frequency alternating voltage to the assembly for the limiting inductor and the lamp, whereby the ballast has a single characteristic curve, and in that the average power consumption of the lamp is determined on the basis of the single characteristic curve of the ballast within the standard regulation trapezoid defining the average consumption of the ballast/lamp assembly. Said ballast has uniform regulation characteristics, high electrical efficiency, a unitary power factor, low harmonic distortion, a high ballast efficiency factor, and a low stroboscopic effect.
Patent CA-2268497-C (CA)
Title: Internet subscriber profile
Inventor: LAPIERRE MARTINE
IPC: H04L29/06
Filed: 1999-04-19
Granted: 2008-03-11
Abstract: The internet access unit allows the internet services required by the user to be accessed whilst other services are not available to that user.
Patent CA-2270978-C (CA)
Title: Procede et appareil permettant de determiner des pressions associees a l'oreillette gauche
Inventor: HICKEY DONALD D
IPC: A61M25/00
Filed: 1996-11-04
Granted: 2008-06-03
Abstract: Cette invention concerne un appareil et un procédé non invasifs ne nécessitant pas la présence d'un médecin pour l'utiliser, et qui sont capables de fournir des évaluations quantitatives des valeurs de pression de l'oreillette gauche. Selon le procédé on introduit, à l'aide d'un cathéter (22), un ballonnet (24) dans l'oesophage et on positionne le ballonnet (24) à proximité de l'oreillette gauch. On gonfle graduellement le ballonnet (24). On mesure par oscillométrie la pression moyenne du ballonnet lorsque l'intensité d'une onde sonore, après émission à travers le ballonnet (24), se situe à une crête. Cette pression moyenne du ballonnet après ajustement pour tenir compte le cas échéant du poids du coeur indique la pression moyenne approximative de l'oreillette gauche. On peut déterminer la pression moyenne de l'oreillette gauche en compensant les effets du poids du coeur et de la pression intrapleurale sur la pression moyenne (PM) à une intensité de crête de l'onde sonore, de laquelle (PM) on soustrait la pression du ballonnet à laquelle le volume du ballonnet commence à augmenter fortement par rapport à l'augmentation de la pression du ballonnet.
Patent CA-2275433-C (CA)
Inventor: HOLLER JAN
IPC: H04L12/54
Filed: 1997-12-19
Granted: 2007-05-01
Abstract: Narrowband based telephony services and associated value added services are provided transparently in a network providing ATM switching and no STM switching is required in an ATM network (625) to which units (601, 603) requiring such services are connected. This is obtained by means of, when a call enters the ATM network (625), first finding the output port (619) from the ATM network (625), then returning the address of that port to the entry port (617) and thereafter ATM switch the connection directly through the ATM network (625). Hereby bandwidth resources are more efficiently used since all switching is done by ATM regardless of application. Heavy investments in providing intelligent services support by existing systems can be reused in an efficient way and thus reduce time to market for the introduction of the value added services.
Patent CA-2279031-C (CA)
Inventor: MYER ROBERT EVAN
IPC: H04B3/10
Filed: 1999-07-29
Granted: 2002-01-22
Abstract: A control system comprising an electrical circuit that produces distortion where the electrical circuit has a frequency band of operation. A pilot modulated carrier signal is generated and is cause to traverse across the frequency band of operation of the electrical circuit. Information obtained from the traversing pilot modulated carrier signal when it is determined that there is no interference between any signal applied to or generated by the electrical circuit. The information is used by the control system to substantially cancel the distortion.
Patent CA-2289209-C (CA)
Title: Cyclic ether vitamin d3 compounds, 1.alpha. (oh) 3-epi-vitamin d3 compounds and uses thereof
Inventor: REDDY SATYANARAYANA G
IPC: C07D307/33
Filed: 1998-05-15
Granted: 2006-07-25
Abstract: Novel cyclic ether vitamin D3 compounds having a cyclic ether side chain are disclosed. These compounds were first identified as metabolites of 3-epi vitamin D3 produced via a tissue-specific metabolic pathway which catalyzes the formation of a cyclic ether structure. Also disclosed are 1.alpha.(OH) 3-epi vitamin D3 compounds, which are produced via the epimerization of a 3-.beta.-hydroxyl group of 1 .alpha.(OH) vitamin D3 precursor in vivo. The vitamin D3 compounds of the present invention can be used as substitutes for natural and synthetic vitamin D3 compounds.
Patent CA-2297617-C (CA)
Title: Gps navigational system for aerospatial applications
Inventor: MITTNACHT MICHAEL
IPC: G01S1/04
Filed: 2000-02-02
Granted: 2006-04-11
Abstract: The invention concerns a GPS navigational system for aerospatial applications with an antenna which is connected to a front-end (3) via a signal line (11), which is controlled by a clock (5), and with a signal processor (7) for the generation of raw data required for the navigational solution and directly exchanging data with the board computer (9) via a data bus line (25).
Patent CA-2298920-C (CA)
Title: Tank cleaning apparatus
Inventor: HEATH ROBERT A
IPC: B01F15/00
Filed: 2000-02-17
Granted: 2007-01-09
Abstract: Crude oil tank cleaning apparatus includes a gimbal having a substantially straight passageway extending therethough. A mounting bracket sealingly and rotatably mounts the gimbal in a wall of the tank so that the gimbal has an interior side exposed to the interior of the tank and an exterior side exposed to the exterior of the tank. A straight pipe is sealingly mounted in the gimbal passageway. The pipe has an inlet end on the exterior side of the gimbal for connecting the pipe to a high pressure fluid source and an outlet end on the interior side of the gimbal such that the inlet and outlet ends define a linear flow passageway through the pipe for discharging the fluid in fluid jet into the tank. An actuator, mounted on the exterior of the tank, has a first end connected to a rotatable portion of the gimbal and a second end connected to a stationary portion of the tank or the mounting bracket for reciprocating the gimbal and pipe between selected positions.
Patent CA-2300602-C (CA)
Title: High purity carbon black composition in the form of a powder obtained by pyrolysis of a solid carbonizable material, process thereof
Inventor: LAMOTHE JEAN-PIERRE
IPC: C09C1/48
Filed: 2000-03-10
Granted: 2008-11-18
Abstract: A high purity carbon black composition in the form of a powder, resulting from the pyrolysis of a solid carbonizable material comprising: - more than 75 per cent of carbon black, - less than 0.0002 per cent of arsenic, - less than 2 per cent of chloride(s), - less than 0.03 per cent of copper, - less than 5 per cent of zinc, and - impurities. The percentages are expressed in weight with respect to the total weight of the composition and the composition has a total hydrocarbon content lower than 0.5 per cent. Such a composition is obtainable by a pyrolysis process of a solid carbonizable material wherein a rotary reactor comprising wings attached to the internal surface of the cylindrical body in a line by line shifted pattern is used. The recovered composition is directly useful in the plastic and rubber product industry, and more particularly in the tire industry.
Patent CA-2300823-C (CA)
Inventor: FOSBENNER MARY ELLEN G
IPC: A63H33/30
Filed: 1998-08-18
Granted: 2006-10-10
Abstract: A toy kit includes a plurality of ring bases (12), ring gems (14) and/or ring domes (16). A first workstation (18) for the ring base (12), and ring gem (14) or ring dome (16), includes a base (46) and an upright support structure (48) having a ram (50) movably mounted (48) to move toward and away from base (46). The kit also has a hollow, flexible tube (20) having at least one open end (22A), and a plurality of particulate substances (24) and liquid substances (26). A second toy workstation (28) for the tube includes a base (70) and an upright support structure (72) having a passage (30) to accommodate particulates, and a carriage (76) movably mounted to the support structure (72) having a holder (78) for the tube (20). A linkage (80), connected with the carriage (76), moves the holder (78) toward and away from the passage (30). After particulates and/or liquids are inserted into the tube (20), a loop is formed by inserting a connector (23A, 23B) into both ends of the tube (20).
Patent CA-2301590-C (CA)
Title: 2-aminopyridines as inhibitors of cyclooxygenase-2
Inventor: FRIESEN RICHARD
IPC: C07D401/04
Filed: 1998-09-11
Granted: 2007-05-01
Abstract: The invention encompasses the novel compound of Formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasse s certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediat ed diseases comprising compounds of Formula (I).