baber/WOPTO huggingface dataset:
Patent PT-958371-E (PT)
Inventor: BISCHOFF JAMES R
IPC: C12N15/861
Filed: 1997-12-10
Abstract: Methods and compositions for treating neoplastic conditions by viral-based therapy are provided. Mutant virus lacking viral proteins which bind and/or inactivate p53 or RB are administered to a patient having a neoplasm which comprises cells lacking p53 and/or RB function. The mutant virus is able to substantially produce a replication phenotype in neoplastic cells but is substantially unable to produce a replication phenotype in non-replicating, non-neoplastic cells having essentially normal p53 and/or RB function. The preferential generation of replication phenotype in neoplastic cells results in a preferential killing of the neoplastic cells, either directly or by expression of a cytotoxic gene in cells expressing a viral replication phenotype.
Patent PT-973626-E (PT)
Inventor: ECKGOLD ROLAND
IPC: B23F21/26
Filed: 1998-04-01
Abstract: In order to manufacture parts with an outer profile, a workpiece 32 is pressed by a pressure piece 24 through a ring-shaped cutting tool 34. The cutting tool 34 has a plurality of disks with inner cutting edges 62 for removing material from the workpiece 32. The cutting edges are progressively longer in the advance direction, so that each cutting edge removes material chips and the last cutting edge in the advance direction corresponds to the desired outer profile of the part. In order to improve chip removal, the chip chambers 74 located between the cutting edges communicate with the outside through radial connection openings 128 which are distributed all around their circumference. To hold the workpiece 32 securely on the pressure piece 24, a pressure pad 76 extends through the cutting tool 34 and is supported on the side of the workpiece 32 opposite to the pressure piece 32, and a hydraulic piston 80 generates a compression force on the pressure pad 76. To ensure a high dimensional accuracy, a calibrating tool with a passage whose dimensions at the rear outlet side correspond to the set dimensions of the part to be manufactured is arranged behind the cutting tool.
Patent PT-1005390-E (PT)
Inventor: SEGERS JACOBUS CORNELIS
IPC: B01D71/34
Filed: 1998-07-23
Abstract: Oils, extracted from vegetables and animal tissues contain impurities such as waxes that can be removed in a refining process, including dewaxing of the oils that include removal of oils by filtration through membranes. During filtration, the impurities stick to the membranes, which causes a reduction in flux through the membranes. The initial top flux can be approached again by regularly cleaning the membranes including steps of: backblowing with gas, backflushing with edible oil, and treating the membranes with alkaline material. The cleaning method is particularly suitable for cleaning membranes in the form of microfilters having an average pore diameter of 0.5-5 mum, which are used in the refining process.
Patent PT-1231875-E (PT)
Inventor: RAINER KRUPPA
IPC: A61F7/00
Filed: 1999-12-22
Abstract: The invention relates to a device used for treatment of the sequelae of insect stings and bites. The objective of the invention is to provide a device for thermal treatment of insect stings and bites, whereby the amount of heat required to neutralize thermolabile insect toxin is provided irrespective of external conditions without resulting in irritations of the skin due to the effects of heat. This is achieved by means of a device comprised of a heating element (1) embodied as an electric heating plate (2) which is supplied with power from a voltage source (3). In the heat-up phase, said heating plate (2) is heated up to a maximum temperature of 50  DEG C - 65  DEG C, preferably 55  DEG C - 60  DEG C. Said maximum temperature is maintained in a heating phase for a duration of 2-12 secs, preferably 3-6 secs.
Patent PT-1143958-E (PT)
Title: Pharmaceutical composition and use of rnsaid for treating inflammation
Inventor: WECHTER WILLIAM J
IPC: A61K31/192
Filed: 1999-09-03
Abstract: This invention relates to the use of enantiomerically pure R-NSAIDs for the treatment of inflammation. Preferably, the R-NSAID used is R-flurbiprofen and is administered in a dose of at least 5 milligrams per kilogram of body weight per day. The anti-inflammatory action of R-NSAIDs is due to their ability to interfere with the biosynthesis of COX-2 by inhibiting COX-2 mRNA synthesis, rather than by just blocking the action of the enzyme itself. In order to effect the inhibition of COX-2 mRNA synthesis, the R-NSAID must be present at relatively high doses. Because the R-NSAID is selective in its action, that is, it does not inhibit either COX-1 mRNA synthesis or the COX-1 enzyme itself, it can be administered in the required high doses because the tissue protective effects of prostaglandins made through the COX-1 pathway are not interfered with.
Patent SG-30579-G (SG)
Title: CD player
Inventor: BAAS DIETER
IPC: G11B27/00
Filed: 1988-01-22
Abstract: In CD players, part of the redundant content description of a CD is entered in a memory. Because, at the start of entry, the positioning of the scanning light beam has a random character, it can sometimes be a relatively long time before the light beam strikes the first block (AO) of the content description at which storage begins. 
<??>To reduce the entry time in the memory, the light beam is guided from the block which it strikes at random at the beginning until the first block (AO). According to a second solution, the data to be stored is stored, starting with the block which the light beam strikes at random at the beginning, up to the next block of the same content. In a third solution, storage begins at the block which the light beam strikes at random at the beginning. When the last block to be stored is reached, the light beam jumps to the first block (AO) in order to store the remaining data.
Patent IE-35378-L (IE)
Title: Erythromycylamine compounds
IPC: C07H17/08
Filed: 1971-02-09
Abstract: 1341022 Erythromycylamine compounds LILLY INDUSTRIES Ltd 31 Dec 1970 [13 April 1970] 17529/70 Heading C2A A process for preparing erythromycylamine compounds of the Formula I wherein R 1 and R 2 are different and are a hydrogen atom or an amino group, R 3 is a hydrogen atom or a hydroxy group, R 4 is a cladinosyl group and R 5 is a desosaminyl group, which process comprises reducing an erythromycin oxime of general Formula II wherein R 6 is an = NOH group and R 3 , R 4 and R 5 are as defined for Formula I, with transition metal ions, e.g. Ti<SP>3+</SP>, V<SP>2+</SP> or Cr<SP>2+</SP>, said ions, these ions being in a low valence state and of suitable redox potential so as to reduce the oxime to an intermediate reaction product (identified as an imine, i.e. R 6 is =NH) and thereafter reducing the imine to form the erythromycylamine compound. The imine may be reduced to the corresponding erythromycylamine compound by use of a complex metal hydride, hydrogen in the presence of a catalyst or an electropositive metal such as sodium or aluminium. A process for preparing erythromycyl A imine and B imine by stopping the reduction at an intermediate stage. The invention also comprises erythromycylamine A and B compounds and their epimers and the corresponding A and B imines when prepared by the above processes. Further, the invention comprises pharmaceutical compositions containing at least one of the above compounds in conjunction with a pharmaceutically acceptable carrier. There are also provided compositions for treating walls, floors, furnishings, &c. in the form of aqueous solutions containing at least one of the above erythromycylamine compounds, optionally in conjunction with a surface-active agent.
[GB1341022A]
Patent IE-36075-L (IE)
Title: Separation of diamonds using radiation
IPC: B07C5/346
Filed: 1972-02-10
Abstract: 1384813 Uses of luminescence DE BEERS CONSOLIDATED MINES Ltd 10 Feb 1972 [12 Feb 1971] 6296/72 Heading C4S [Also in Division G1] Diamonds are sorted from a mixture by irradiating the mixture, detecting luminescence therefrom and dividing the diamonds into fractions in accordance with different spectral characteristics. The radiation may be γ-rays from a Co 60 source, X-rays from an X-ray tube or ultra violet radiation from a lamp which may require a u.v. filter. A grating spectrometer provided with a choice of photomultipliers to cover the full spectral range, or a plurality of filters, may be used for the spectral analysis. Characteristics which may be used in combination may be the unique spectra of the different types of diamonds and common impurities (spectral signatures), ratios of different parts of the spectra or decay characteristics. A compressed air blast sorter may be used on a single particle stream on a conveyer belt or freely falling. Various examples of luminescence characteristic spectra are provided (not shown) for four types of diamond, zircon and fluorite, at room and liquid nitrogen temperatures.
[GB1384813A]
Patent IE-850169-L (IE)
Title: Nonradiometric polynucleotide probes
IPC: C12N15/09
Filed: 1985-01-25
Abstract: Nonradiometric polynucleotide probe compositions comprising zymogen-activating polypeptide reporter moieties are disclosed, in addition to detection methods and systems employing said probes.
[US4699876A]
Patent IE-37309-L (IE)
Title: Silicate-coated microcapsules
IPC: B01J13/02
Filed: 1973-02-21
Abstract: A capsule comprising a core which includes polar group affording organic material (and non-reactive material) and a membrane reaction product of inorganic silicate and polar groups of the core polar group affording organic material.
[US3852076A]
Patent IE-45597-L (IE)
Title: Cephalosporins.
IPC: C07D501/36
Filed: 1977-03-01
Abstract: Novel syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds are provided of the formula: <IMG> in which R1 is a group of the formula: <IMG> wherein R5 is hydrogen, halogen, nitro, hydroxy, lower alkoxy or acyloxy and R6 is hydroxy, lower alkoxy, acyloxy, acylamino or di(lower)alkylamino; a group of the formula: <IMG> wherein R7 is amino, protected amino, hydroxy or lower alkyl; or a group of the formula: <IMG> wherein R8 is lower alkyl and R9 is imino, protected imino or oxo; R2 is an aliphatic hydrocarbon group which may have suitable substituent (s); R3 is carboxy or protected carboxy; and R4 is acyloxymethyl, hydroxymethyl, formyl or a heterocyclicthiomethyl group which may have suitable substituent (s); or R3 and R4 are linked together to form -COOCH2-, and pharmaceutically acceptable salts and tautomers thereof; the novel compounds are highly active against a number of pathogenic bacteria. 
(From CA1337522 C) 
[FR2348219A1]
Patent IE-39206-L (IE)
Title: Curing agents for epoxy resins
IPC: C08G59/18
Filed: 1974-04-08
Abstract: Adduct of a phthalic anhydride and an amino-amide of monomeric, epoxidized fatty compounds, which is a new curing agent for epoxy resins, particularly suitable for curing such epoxy resins in aqueous systems. The agents find utility in cement extended systems such as floorings, i.e. terrazo flooring, but are also useful in any area where thermoset epoxy systems find utility, such as coating systems, i.e. paints.
[US3873481A]
Patent IE-44678-L (IE)
Title: Accumulator casing
IPC: H01M50/262
Filed: 1977-04-13
Abstract: The construction of the lead-acid accumulator is intended to make the known attachment types possible for vehicles by means of attachment strips. The lead-acid accumulator is intended to be capable of attachment to different vehicles without further modifications. The plastic housing (2) of the lead-acid accumulator (1) is provided in the region of its base, on the side walls (4, 5, 6, 7), with in each case one attachment strip (9, 11) of integral construction. These attachment strips (9, 11) supplement one another to form a continuous attachment strip, only the edge regions being cut out. On the two narrow sides (4, 6), the attachment strips are provided centrally with a notch which is used to improve retention. The upper surface of the projecting attachment strips (9, 11) is bevelled in a roof shape. The upper surface of the attachment strip, which is bevelled in a roof shape, merges on the narrow sides (4, 6) of the housing (2) at right angles into a bevelled lower surface or supporting profile (14) of an upper attachment strip (15, 16), in each case on a narrow side (4, 6) of the housing (2). The upper surface of the upper attachment strips (15, 16) is likewise of bevelled construction and is in each case provided with a notch (12, 13) which is aligned with the notch mentioned above. <IMAGE>
[GB1571712A]
Patent IE-37642-L (IE)
Title: Window frames
IPC: E06B7/084
Filed: 1973-05-17
Abstract: 1427324 Window drain valve BETA ALUMINIUM PRODUCTS Ltd 16 May 1973 [26 May 1972] 24863/72 Heading EIJ A window frame includes a hollow sill for collecting condensation from the window's interior and an outlet opening to the winrow's exterior and closed by a resilient flap valve 28 mounted in a plastics block 20 fitted in the sill, the valve being operable by the head of water built up in the sill. The valves are of neoprene and are formed in hollow, plastics blocks 20 located at each end of the sill. The blocks also communicate with the uprights of the frame. For Figure see next column
[GB1427324A]
Patent IE-860901-L (IE)
Title: Method for the prevention of restenosis
IPC: A61F2/958
Filed: 1986-04-08
Abstract: A process for local administration of heparin or other agents to inhibit smooth muscle cell proliferation utilizing a catheter. The catheter has two balloons (8, 9) and an optional balloon (10), inflation passages (5, 6) and a heparin infusion channel (7) therein. The end balloons (8, 9) form a chamber when inflated and inserted into a blood vessel to retain heparin injected there into. The middle balloon (10) may be inflated to perform angio-plasty.
[WO8605990A1]
Patent IE-39443-L (IE)
Title: Pharmaceutical compositions; 5-(substituted benzal)¹hydantoin derivatives
IPC: C07D405/06
Filed: 1973-06-15
Abstract: 1434074 Medicines comprising hydantoin derivatives CANADA PACKERS Ltd and UNIVERSITY OF MONTREAL, INSTITUTE OF MICROBIOLOGY and HYGIENE 11 June 1973 [16 June 1972] 27614/73 Heading A5B Pharmaceutical compositions having antiviral activity comprise a carrier or a compound of the formula: wherein R1, R2 and R3 may each be H, halogen, hydroxy, C1-4 alkoxy, C1-4 acyloxy or nitro or R1 and R2 together represent the methylene dioxy group or an acetylated derivative thereof in which the hydantoin moiety is substituted by one or two acyl groups each containing from 1 to 20 carbon atoms. They may be in forms suitable for oral or parenteral administration which comprise conventional carriers and excipients.
[GB1434074A]
Patent IE-37834-L (IE)
Title: 3 - amino - pyrazolenes - (5).
IPC: C07D231/44
Filed: 1973-06-22
Abstract: 1391051 Aminopyrazolones BAYER AG 22 June 1973 [23 June 1972] 29785/73 Heading C2C The invention comprises compounds of the tautomeric formulae and their salts, wherein R is (a) a phenyl radical carrying one or two identical or different substituents selected from alkyl, phenyl, trifluoromethyl, trifluoromethoxy, nitro, nitrile, carbamoyl, sulphamoyl, alkylamino, fluorine, bromine and iodine radicals but cannot be a phenyl radical carrying trifluoromethyl only as one substituent, or (b) a phenyl radical carrying an annellated, branched or unbranched, saturated or unsaturated, five to seven-membered isocyclic or heterocyclic ring (the heterocyclic ring containing one or more oxygen and/or sulphur atoms); or (c) a phenyl radical carrying as substituent an SO n -alkyl group (n = 0, 1 or 2), an alkoxy group, or an -O-(CH 2 ) n -N(alkyl) 2 group (n = 2 or 3); or (d) a phenyl radical carrying two identical substituents selected from alkoxy and trifluoromethyl groups; or (e) a phenyl radical carrying two different substituents selected from alkyl, phenyl, halogen, alkoxy, trifluoromethyl, trifluoromethoxy, alkylamino, nitrile, carbamoyl, sulphamoyl, -SO n alkyl (n = 0, 1 or 2) and nitro radicals; or (f) a trichlorophenyl radical; or (g) a naphthyl radical carrying one or two identical or different substituents selected from halogen atoms and alkyl groups; or (h) an unsubstituted #-naphthyl, anthryl or phenanthryl radical. These compounds are prepared by reacting RCH 2 NHNH 2 with CNCH 2 COX or where X is OH, alkoxy, aralkoxy, NH 2 or alkylamino, and Y is alkoxy, aryloxy, aralkoxy, alkylmercapto, aralkylmercapto or NH 2 . Therapeutic compositions having diuretic, saluretic and antihypertensive activity comprise compounds of the above formulae, and may be administered orally, parenterally, rectally, topically or by means of a spray.
[GB1391051A]
Patent IE-851182-L (IE)
Title: Sealing canisters
IPC: B21D51/30
Filed: 1985-05-13
Abstract: A packaging container is closed by using a double seam 152 to secure over the container body 70 a cover 74 of smaller diameter than is usual, creating a radial space 104 around the cover chuck wall 122 into which the body sidewall 72 is deformed to form a neck 76. The cover is initially placed on the body to form a sealable interface 142 therebetween, this interface being preserved throughout the seaming process. The body and/or the cover may be of plastics or metal or a laminated material. In an aseptic packaging process, a primary seal is created at the interface 142 under sterile conditions, seaming subsequently being carried out under non-sterile conditions.
Patent IE-35744-L (IE)
Title: Removing hides from carcasses.
IPC: A22B5/16
Filed: 1971-10-18
Abstract: A beef carcass suspended at the hind legs from a moving conveyor, is prepared for hide removal by means of a deep rumping operation performed by hand which frees the tail and provides at each side of the carcass a hide flap. The underside of the hide is slitted down to the forequarters and head, and a pocket is formed at the top of the loin to free the tail and prevent the fat in this region from being pulled off as the hide is stripped from the pack, sides, forelegs, and head in one continuous rapid operation, the head remaining on the carcass.
[US3737949A]
Patent IE-821343-L (IE)
Title: Security barrier
IPC: E05G1/024
Filed: 1982-06-03
Abstract: A barrier structure for the walls and/or doors of a safe or other security enclosure comprises a corrugated planar element (2) of copper or other tough and heat-resistant metal disposed in intimate relation within a matrix (3) eg of cast aluminium or concrete containing elements (4) of very hard and refractory material. The corrugations in the element (2) are formed so as to ensure that a cutting tool of selected diameter which is applied to that element (2) will inevitably encounter some of the hard material (4) behind that element (2) so that the tool is blunted before the element (2) can be completely penetrated.
Patent IE-891462-L (IE)
Title: Immunostimulating guanine derivatives, compositions and¹methods
IPC: C07H19/167
Filed: 1989-05-04
Abstract: 7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are =O, =S, =Se and =NCN. Compositions and methods of use are also disclosed.
Patent IE-901742-L (IE)
Title: Composition for reducing gastrointestinal disorders
IPC: A23L29/00
Filed: 1990-05-15
Abstract: A composition is provided for ingestion by mammals for in vivo conversion of alpha-D-galactoside comprising an amount of alpha-galactosidase effective to hydrolyze alpha-D-galactoside to D-galactose, and non-toxic, ingestible excipients(s) for said alpha-galactrosidase. Gastric distress in mammals due to ingestion of foods containing alpha-D-galactoside may be reduced by ingesting the foregoing composition of alpha-galactosidase and non-toxic, ingestible excipient contemporaneously with the ingestion of said food in an amount effective to hydrolyze the alpha-D-galactoside to D-galactose.
Patent IE-44023-L (IE)
Title: Insecticidal preparations
IPC: C08K5/00
Filed: 1976-08-25
Abstract: In an insecticidal article comprising an insecticidally effective amount of at least one volatile phosphoric or thiophosphoric acid ester and a solid polyurethane carrier material, the improvement wherein said polyurethane is an elastomeric polyurethane, whereby the article retains its activity over a long period of time. The polyurethane is formed of a polyisocyanate and a mixture of a long chain polyol and a short chain polyol and/or polyamine.[US4094970A]
Patent IE-38441-L (IE)
Title: Illuminated sign
IPC: G09F11/00
Filed: 1973-10-31
Abstract: 1394319 Illuminated signs; hoardings R V TCHAKGARIAN 1 Nov 1973 [2 Nov 1972] 50817/73 Heading G5C A sign comprises two ventical arrays of horizontal symbol-carrying translucent plastics panels 4 which are so inclined that a louvred arrangement is formed whereby wind passes unhindered through the sign, but light from internal sources 5 or 6 cannot reach an observer between the panels. The panels are secured to the ends of rod 7 vertically spaced on uprights 3 which are welded to channel sections 1 of a frame 2. Provision for thermal expansion of the panels is included.
[GB1394319A]
Patent IE-42612-L (IE)
Title: Penicillanic acid derivatives.
IPC: A61P31/04
Filed: 1975-10-20
Abstract: Penicillanic acid derivatives of the formula <IMAGE> I wherein E is selected from the group consisting of hydrogen, a salt forming cation, and an ester forming residue which is known to improve the absorption characteristics of penicillanic compounds after oral administration to humans or animals, and Y is a group of the formula <IMAGE> II wherein Z1 and Z2 are individually selected from the group consisting of lower alkoxy, optionally substituted phenoxy, optionally substituted benzyl and benzyloxy group, optionally substituted lower alkyl, optionally substituted phenyl, hydroxy and -OM wherein M represents a salt forming cation, and hydrates of the said salts having antibacterial properties and their preparation and novel intermediates.
[US4067986A]
Patent IE-832784-L (IE)
Title: Manhole cover
IPC: E02D29/14
Filed: 1983-11-28
Abstract: In a manhole or access cover having at least one recess into which a key or other implement can be inserted to enable the cover to be lifted or levered from its frame, the recess comprises two undercut apertures 16, 17 of different depth with a step 14 between them, and a crossbar 15 extending across the mouth of the recess at a location spaced above the step. The crossbar 15 has a rebate on its underside. The specification illustrates a variety of known lifting tools for which the recess is suitable-namely (a) a rod having opposed rectangular ears for quarter-turn interlock; (b) the hooked bar 24 shown; (c) a pair of inter-pivoted caliper arms; (d) two forms of lifting lever or handle which are clamped to the cover by screw- threaded means; (e) a pick-axe head. <IMAGE>
[GB2133444A]
Patent NO-823997-L (NO)
Inventor: SNIDER SCOTT C
IPC: C08G18/42
Filed: 1982-11-29
Abstract: Cellular foams, particularly polyisocyanurate foams, are prepared by reacting together an organic polyisocyanate, a blowing agent, a trimerization catalyst, and a minor amount of a polyol mixture prepared by the transesterification with a glycol of a by-product fraction from the manufacture of dimethyl terephthalate, the major portion of said fraction comprising about 15 to 70 weight percent of dimethyl terephthalate, and about 85 to 30 weight percent of a mixture of monomethyl terephthalate, bi-ring esters and polymeric materials. Laminates of such foams exhibit a high degree of fire resistance, low smoke evolution on combustion, low foam friability and high compressive strength.