baber/WOPTO huggingface dataset:
Patent CA-2486480-A1 (CA)
Title: Improved kavalactone profile
Inventor: BIRDSALL WILLIAM
IPC: A61K36/48
Filed: 2002-10-18
Abstract: A method of producing a processed kava product involves using an extraction solvent, such as liquid CO2 to preferentially extract different kavalactones from the source material at different rates. By controlling the extraction parameters and stopping the extraction before all of the kavalactones have been extracted or allowing the extracted kavalactones to be preferentially precipitated in one or more collection environments, a processed kava product can be produced that has a kavalactone distribution profile that can differ substantially from that of the source material. As a result, roots from a less desirable kava cultivar can be used to produce a processed kava product which has a kavalactone distribution profile that is similar to that of a highly desired cultivar. A material having a preferred kavalactone distribution profile is also disclosed. The kava paste can be further processed to produce a dry flowable powder suitable for use in, e.g., a tableting formula. A rapid dissolve tablet formulation for use in the delivery of kavalactones is also disclosed.
Patent CA-2487142-A1 (CA)
Inventor: LIVINGSTONE DAVID E
IPC: B05C11/02
Filed: 2004-11-05
Abstract: A spreading apparatus is provided for spreading flowable materials such as adhesives and/or sealants on a surface such as a floor and/or a wall. The apparatus has a pad retainer for retaining a removable spreader pad and a reservoir chamber for flowable material pivotally attached to the pad retainer to permit pivoting of the reservoir chamber frontwards and backwards. The spreader pad comprises an elongated resilient foam member sufficiently thick to fit within and frictionally engage the pad retainer, and sufficiently high to extend below the pad retainer so that the spreader pad rather than the pad retainer contacts the surface when the spreader pad is retained by the pad retainer.
Patent CA-2488817-A1 (CA)
Inventor: MORI HIROSHI
IPC: B29K67/00
Filed: 2003-07-11
Abstract: A process for laser welding together a laser beam transparent polyester article and a laser beam opaque polyester article. The method limits the use of a laser beam at an energy level not greater than 100 W at a scanning spee d not greater than 1000 cm/min., thus causing the articles to be welded togeth er and maintaining a high weld strength.
Patent CA-2491129-A1 (CA)
Inventor: LENCER WAYNE I
IPC: A61M/
Filed: 2003-05-09
Abstract: The present invention relates to methods and products for the transepithelial systemic delivery of therapeutics. In particular, the invention relates to methods and compositions for the systemic delivery of therapeutics by administering an aerosol containing antibodies or conjugates of a therapeutic agent with an FcRn binding partner to epithelium of central airways of the lung. The methods and products are adaptable to a wide range of therapeutic agents, including proteins and polypeptides, nucleic acids, drugs, and others.  The methods and products have the advantage of not requiring administration to the deep lung in order to effect systemic delivery.
Patent CA-2491513-A1 (CA)
Inventor: YEH LEE-CHUAN C
IPC: A61K35/32
Filed: 2003-07-09
Abstract: The present invention provides methods and compositions for treating and repairing ligament defects using a bone morphogenic protein. The present invention provides methods of treating ligament defects, repairing ligament defects, forming ligament tissue, regenerating ligament tissue, and promoting growth of ligament tissue by transplanting into a patient in need thereof ligament cells cultured ex-vivo.
Patent CA-2492900-A1 (CA)
Inventor: TORTORELLA DENNIS J
IPC: B65D41/34
Filed: 2003-07-22
Abstract: Une fermeture pour un récipient à boisson comprend: (a) une base prévue pour être fixée à une ouverture d'un récipient à liquide, ladite base comprenant un conduit qui la traverse et qui est prévu pour communiquer par le fluide avec le contenu liquide du récipient à liquide. Ladite base comprend également un guide de goulot sensiblement tubulaire définissant au moins une partie du conduit et un pont annulaire s'étendant radialement à l'intérieur depuis une surface circonférentielle interne de la base définissant un orifice central qui communique par le fluide avec le conduit. La fermeture selon l'invention comprend également (b) un goulot sensiblement annulaire installé sur le guide-goulot tubulaire pour effectuer un mouvement alternatif au moins entre une position ouverte et une position fermée, le goulot comprenant (1) une paroi annulaire et (2) un bouchon positionné radialement à l'intérieur de la paroi annulaire; ledit bouchon comportant une surface d'étanchéité circonférentielle externe annulaire qui se loge à l'intérieur, et bouche l'orifice central du pont lorsque le goulot se trouve en position fermée et qui est enlevée du pont de l'orifice central lorsque le goulot se trouve en position ouverte. Au moins une partie substantielle de la surface d'étanchéité externe circonférentielle du bouchon est évidée axialement ou affleurante par rapport à la paroi annulaire du goulot; ladite surface d'étanchéité externe circonférentielle présente soit une forme cylindrique lisse à diamètre sensiblement constant soit une forme de cône tronqué lisse dont le diamètre s'élargit en fonction de la distance qui le sépare de l'extrémité avant.
Patent CA-2493143-A1 (CA)
Inventor: RODRIGUEZ-SARMIENTO ROSA MARIA
IPC: A61P25/00
Filed: 2003-07-31
Abstract: La présente invention concerne des dérivés de 2,3-dihydro-isoindol-1-one, des procédés pour les produire, leur utilisation en tant que produits pharmaceutiques, ainsi que des compositions pharmaceutiques les comprenant, qui permettent de prévenir et de traiter des maladies dont la médiation est assurée par des inhibiteurs de monoamine oxydase B.
Patent CA-2493199-A1 (CA)
Inventor: PLATZEK JOHANNES
IPC: A61P25/16
Filed: 2003-07-12
Abstract: L'invention concerne l'utilisation de dérivés de porphyrine paramagnétiques substitués en 3 et en 8, avec différents substituants en positions 13 et 17 du squelette de porphyrine, comme catalyseurs de transformation du péroxynitrite pour traiter et prévenir des maladies caractérisées par une détérioration des cellules induite par des radicaux.
Patent CA-2493567-A1 (CA)
Title: Efficient encryption and authentication for data processing systems
Inventor: HAWKES PHILIP MICHAEL
IPC: H04L9/32
Filed: 2003-07-24
Abstract: Methods and apparatus are presented for encrypting and authenticating data, wherein some data is encrypted and some data is not encrypted, but all of th e data is authenticated. Different formulations for authentication blocks are used according to whether a block of data occupies a cleartext position (442 A, 442B, 442C) or ciphertext position. (444A 444B, 444C, 444D) The authenticati on blocks are then combined to form a checksum, which is encrypted to form an authentication tag.
Patent CA-2495724-A1 (CA)
Inventor: DYBRO NIELS
IPC: E02F9/20
Filed: 2003-07-12
Abstract: The invention relates to an operating device for triggering an apparatus, particularly for triggering a vehicle. Preferably, said operating device is pivotable and/or rotatable about several axes and comprises an actuator (16) , an actuation lever, and at least one sensor. The actuator (16) is connected to the actuation lever so as to cooperate therewith. The actuation lever is provided with a handle section (14) on which the sensor is arranged so as to actuate the actuator in a connecting and cooperating manner when the handle section (14) of the actuation lever is duly gripped in a manual manner. The inventive operating device is actuated only if the operator duly grips the operating device, unintentional actuation thereof being prevented while the positive ergonomic characteristics thereof are largely maintained.
Patent CA-2495755-A1 (CA)
Title: Compounds comprising phosphorus-containing metal complexes
Inventor: LECLOUX DANIEL DAVID
IPC: C07F15/00
Filed: 2003-08-15
Abstract: Compounds comprising phosphorus-containing metal complexes can be used in electroluminescent devices and have an emission maximum closer to the blue region of the visible light spectrum. The complexes can be used within an organic active layer in electronic devices, such as displays, detectors, voltaic cells, solid-state lighting, illumination devices or the like. The complexes may also be used as catalysts or as indicators in other applications. The new compounds can be used without the need of a host material. In non-limiting embodiments, Pt or Ir may be used for the metal atom within the complex, one ligand may include a phosphorus-containing bidentate ligand, and another ligand may include a monoanionic bidentate ligand. The phosphorus-containing bidentate ligand may include a benzyl group, a phenoxy group, a phenylamino group, or the like.
Patent CA-2497892-A1 (CA)
Inventor: FARRAR GWYNETH JANE
IPC: C12N15/11
Filed: 2003-09-04
Abstract: Methods and reagents are provided for the tissue specific, cell specific and/or inducible expression of RNAi. The invention may be used to downregulate the expression of endogenous or exogenous RNAs targeted by the RNAi in cells, animals and/or plants.
Patent CA-2500204-A1 (CA)
Title: Method for rotational moulding of a workpiece comprising a thermoplastic foam layer
Inventor: DOULIN GWENAEL
IPC: B29C41/22
Filed: 2003-09-24
Abstract: The invention concerns a method whereby a foam layer is formed by rotational moulding in a step which consists in heating the foaming polymer which is interrupted before foaming temperature is reached, the process being based on the thermal inertia of the system also including the mould (1) and the layers already placed to complete the heating, without, however its reaching an intensity which would provoke haphazard foaming. The foam layer is uniform and adhesive. The dense layers enclosing the foam layer may be different.
Patent CA-2502720-A1 (CA)
Title: Procede et dispositif pour identifier des micro-organismes
Inventor: KORKEAMAKI MIKA
IPC: C12Q1/689
Filed: 2003-08-07
Abstract: La présente invention concerne un procédé et un dispositif pour identifier au moins un micro-organisme et/ou une espèce de micro-organisme et pour mesurer la fraction d'au moins un micro-organisme et/ou d'une espèce de micro-organisme dans un échantillon. Ce procédé consiste à utiliser deux agents fluorescents différents et à induire une excitation avec de la lumière dans deux longueurs d'onde différentes. L'échantillon est soumis à un écoulement. La présente invention concerne également l'utilisation du procédé et du dispositif susmentionnés pour identifier des micro-organismes et pour mesurer leurs fractions.
Patent CA-2502807-A1 (CA)
Title: Improved archery broadhead with replaceable blades
Inventor: PERKINS DERRICK SR
IPC: A63B65/02
Filed: 2003-10-24
Abstract: A broadhead includes a ferrule for mounting an arrowshaft, the ferrule having a locking portion. At least two blades are mounted on the ferrule (three are used in the preferred embodiment), the blades being coupled to the ferrule in their center portions by notches that mate with the locking portion of the ferrule. A locking nut is mounted on a rear portion of the ferrule for holding the three blades in place on the ferrule when the locking nut is tightened.
Patent CA-2504190-A1 (CA)
Inventor: IFKO STEFAN
IPC: E05D15/22
Filed: 2005-04-14
Abstract: A sliding shoe for a sliding/pivoting window having a shoe body which is of two piece construction. A cam trapped between the two portions of the shoe has a cam-shaped body, which rotates in complementary cam-shaped openings through the shoe portions to expand the shoe laterally, and a chamfered cam-shaped annulus which rotates in a complementary bevelled seat in the shoe body to expand the shoe in a direction perpendicular to the lateral expansion. The shoe is thus locked in position in the frame channel very early in the rotational cycle of the cam, and provide secure locking engagement against the sides, top and bottom of the channel when the sash is pivoted only slightly out of the plane of the frame.
Patent CA-2505576-A1 (CA)
Inventor: SHANLEY JOHN F
IPC: A61F2/06
Filed: 2003-11-10
Abstract: La présente invention se rapporte à un procédé de traitement des occlusions des vaisseaux sanguins dans le coeur, qui consiste à délivrer un agent angiogénique à partir d'un dispositif implantable, localement sur les parois des vaisseaux sanguins pendant une période d'administration prolongée suffisante pour produire des vaisseaux sanguins autosuffisants. Un dispositif médical extensible pour l'administration d'agents angiogéniques comporte des ouvertures formées dans les contrefiches du dispositif médical extensible et conçues pour délivrer un ou plusieurs agents angiogéniques favorisant l'angiogenèse. Le dispositif peut délivrer séquentiellement une pluralité d'agents favorisant l'angiogenèse de manière à traiter, par exemple, les troubles et les états pathologiques associés à des occlusions totales chroniques.
Patent CA-2505934-A1 (CA)
Inventor: ELLIS MICHAEL D
IPC: H04N5/782
Filed: 2003-11-05
Abstract: An interactive television system is provided in which a user can use an interactive television application to establish time-based settings. The user may set television program reminders, advance-order payper-view programs, schedule programs for recording, and establish parental controls to prevent television viewing during certain times on certain channels. The interactive television application may be used to support video recorder functions such as personal video recorder functions implemented locally on the user's set-top box or other equipment and network-based video recorder functions implemented using servers at cable television headends and other network locations. The interactive television application may also be used to deliver video-on-demand content. When the user requests that video be delivered, conflicts may arise between the requested video delivery and the previously-established time-based settings. The interactive television application may provide the user with on-screen options that allow the user to select how to resolve these conflicts.
Patent CA-2507233-A1 (CA)
Title: Augmenting flight control surface actuation system and method
Inventor: KRANTZ RICHARD M
IPC: B64C13/42
Filed: 2003-11-05
Abstract: Apparatus (10) for providing actuation power to an aircraft flight control surface. The apparatus includes a first actuator (16) and a second actuator(13), where the second actuator has a bypass mode and an assist mode.  The mode of the second actuator is determined by an internal differential pressure across the first actuator. The apparatus further includes a mode select valve (40) for selecting between the bypass mode and the assist mode for the second actuator, and a solenoid valve (48) that when energized causes the mode select valve (40) to select the other mode for the second actuator.  When the second actuator is in the bypass mode, the first actuator provides the actuation power for the aircraft flight control surface. But, when the second actuator is in the assist mode, both the first and second actuators provide the actuation power for the aircraft flight control surface.  Accordingly, the apparatus allows the flight control surface to be operated in a more efficient manner with less hydraulic flow being required.
Patent CA-2509176-A1 (CA)
Inventor: DAHLQUIST AKE L
IPC: G09F1/12
Filed: 2005-06-03
Abstract: A display easel is provided having a base or first panel which includes a horizontal supporting tab and a vertical restraining tab spaced in vertical relation to the supporting tab. The horizontal supporting tab has a first hinge that enables movement of the supporting tab relative to the panel body, preferably to about 90 degrees, into a position for supporting the first panel. The vertical restraining tab has a second hinge which enables movement of the vertical restraining tab relative to the panel body, preferably between about 120 degrees and 160 degrees, to permit abutment of the vertical restraining tab to the horizontal supporting tab and to restrain movement of the horizontal supporting tab. By restraining movement of the horizontal supporting tab, the display easel is maintained in an upright position. A method of forming a display easel is also provided which enables the display easel to be rapidly and economically manufactured in large quantities, such as through the use of web press equipment.
Patent CA-2509239-A1 (CA)
Title: Carboxylic acid, phosphate or phosphonate substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators
Inventor: BRIELMANN HARRY
IPC: C07F9/6512
Filed: 2003-12-12
Abstract: Acid-substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
Patent CA-2510151-A1 (CA)
Inventor: MCNALLY WILLIAM FRANCIS
IPC: A61F13/00
Filed: 2002-12-20
Abstract: A hydrophilic textile matrix having antibiotic activity is provided. The textile matrix is a non-woven material including a blend (i.e., mixture) of metallic silver-coated fibers and a non-metallic, water absorbent material. Wound dressings incorporating the textile matrices are provided.
Patent CA-2510824-A1 (CA)
Title: Methods for modulation of flow in a flow pathway
Inventor: MCNEILAGE ALAN WATSON
IPC: B01L3/00
Filed: 2005-06-22
Abstract: Methods for modulating the flow of a liquid are provided.
Patent CA-2511576-A1 (CA)
Title: Dispositif de realisation d'ensemble de stockage d'energie electrique par enroulement sur mandrin plat
Inventor: LE GAL GUY
IPC: H01G13/02
Filed: 2003-12-19
Abstract: La présente invention concerne un dispositif de réalisation d'ensembles de stockage d'énergie électrique comprenant des moyens (A, 104, 204, 304) d'alimentation de films multiples et un mandrin (610) adapté pour enrouler ces films multiples sous forme d'un ensemble multi-couches, caractérisé par le fait que le mandrin (610) présente une section non circulaire de révolution et que le dispositif comprend des moyens d'entraînement à rotation du mandrin (610) selon une vitesse angulaire non constante contrôlée de manière à obtenir une vitesse linéaire constante d'alimentation desdits films.
Patent CA-2513532-A1 (CA)
Title: Pearlescent film coating systems and substrates coated therewith
Inventor: FIELDS CHARLES D
IPC: A23L35/00
Filed: 2004-02-13
Abstract: The present invention is directed to film coating systems for use on oral dosage forms such as compressed tablets and orally-ingestible substrates which have improved pearlescent qualities. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the pearlescent film coating is prepared as a dry powder mixture containing a cellulosic polymer, a detackifier, a gloss enhancer, and a pearlescent pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.
Patent CA-2519741-A1 (CA)
Inventor: SAMPSELL JEFFREY B
IPC: H04N5/44
Filed: 2005-09-14
Abstract: One embodiment comprises a system and method of transmitting video data to an array driver bypassing a processor, e.g., a central processing unit. In one embodiment, the transmitted data that bypasses the processor is targeted for display in a particular region of the display. In one embodiment, the size, location, and refresh rate of region is definable by a server or the processor, e.g., application software executing on the processor. In another embodiment, the processor has two communication paths for transmitting video to a display array. The first communication path connects the processor to an array driver. The second communication path connects the processor to a driver controller. In one embodiment, the data that is transmitted to each of the paths targeted for presentation on a selected region of the display. In one embodiment, the size, location, and refresh rate of each of the regions is definable by a server or the processor, e.g., application software executing on the processor.
Patent CA-2520716-A1 (CA)
Inventor: IVERSEN ALAN MICHAEL
IPC: H02K3/04
Filed: 2005-09-23
Abstract: A brazed joint between an armature bar strand package and an end fitting (1 6) includes a plurality of strands (18, 20) arranged in a tiered array and forming the strand package; a cavity (28) in the end fitting, free ends of the plurality of strands extending through the opening (21) and received in the cavity; and an essentially phosphorous-free copper-silver braze alloy (26) joining the free ends of the plurality of strands to each other and to interior surfaces of the end fitting.</SDOAB >
Patent CA-2521525-A1 (CA)
Inventor: BALDWIN LAURA J
IPC: G06F3/048
Filed: 2005-09-28
Abstract: A system and method are provided for implementing a geographic search mode in connection with a search engine.      The method may include indexing geographic locations for resources available to the search engine in a search engine index. The method may additionally include determining a target location for a particular user upon receiving a user query from the particular user and searching the search engine index for geographic location matches matching the target location.
Patent CA-2521841-A1 (CA)
Title: Imidazole derivatives for treatment of allergic and hyperproliferative disorders
Inventor: KHATUYA HARIPADA
IPC: A61K31/4164
Filed: 2004-04-09
Abstract: The preferred embodiments are directed to small molecule inhibitors of the IgE  response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. The preferred embodiments also relate to imidazole molecules that are cellular proliferation inhibitors and thus are useful as anticancer agents. The preferred embodiments further relate to small molecules which suppress cytokines and leukocytes.
Patent CA-2522060-A1 (CA)
Title: Fragments of fluorescent proteins for protein fragment complementation assays
Inventor: MICHNICK STEPHEN WILLIAM WATSO
IPC: G01N33/68
Filed: 2004-04-09
Abstract: The present invention is directed to Protein-fragment Complementation Assays (PCAs) and assay compositions based on fluorescent proteins. The invention provides methods for fragmenting fluorescent proteins and generating mutant fragments with desir4 spectral characteristics for PCA. The invention encompasses assays and compositions based on fluorescent proteins from the species Aequorea, Anemonia and Anthozoa. In particular, the invention is directed to fragments of mutant fluorescent proteins having improved spectral properties over the wild-type proteins. The invention encompasses fragments of mutant versions of A. Victoria green fluorescent protein (GFP), in particular yellow fluorescent proteins (EYFP and super-EYFP), 'Venus', cyan, 'citrine', blue, cyan-green, and photoactivatable variants of GFP. The invention also encompasses red fluorescent PCAs based on Discosoma red fluorescent protein (RFP PCA)and a kindling fluorescent protein PCA (KFP 1 PCA) derived from Anemonia sulcata. Any useful mutation of a fluorescent protein can be engineered into a fragment, generating a wide range of assays useful for drug discovery, target validation, high-throughput screening, high-content screening, pathway mapping, drug mechanism-of-action studies, blosensors, and diagnostics.