baber/WOPTO huggingface dataset:
Patent CA-2260512-C (CA)
Inventor: LYNDE GERALD DAVID
IPC: B23B27/16
Filed: 1999-01-28
Granted: 2005-11-22
Abstract: A method for applying cutting elements to a tool for cutting or milling a metal item in a well is disclosed, along with the cutting element used in the method. The tool can include one or more blades extending outwardly or downwardly from the tool for cutting a metal item such as the wall of a casing string, or for removing a predetermined length of a casing string in a cutting action. The blade or blades have cutting elements positioned on the leading faces of the blades to engage the casing string or other metal item in the bore hole. Each cutting element is composed of a plurality of effective cutting faces. Each cutting face can have a substantially triangular shape, or a substantially square shape, or some other geometric shape. The cutting elements can be arranged in a random pattern. Each cutting element can be oriented in a random orientation relative to the blade. The cutting elements are shaped so that, regardless of the positioning or orientation of a given cutting element, it will continually present a sharp cutting edge to the metal object being cut. Each cutting face of each cutting element can also have one or more surface irregularities to cause the metal chips cut from the casings to break off at short lengths.
Patent CA-2263105-C (CA)
Inventor: VAN VALEY EDWIN T
IPC: A61C11/08
Filed: 1997-08-21
Granted: 2007-10-30
Abstract: Un articulateur pour moulages dentaires comprend deux bras reliés par charnière qui comprennent chacun des segments reliés à une articulation par charnière comportant des éléments d'accouplement, chaque élément d'accouplement étant solidaire par construction à un segment respectif de bras. Un élément comprend deux cymbales qui sont coaxiales sur un axe charnière principal et une face concave qui piègent par résilience entre eux un noeud de l'élément d'accouplement situé sur l'autre segment qui se présente sous forme de convexités opposées donnant sur l'extérieur. Le mouvement multiaxial entre les segments de chaque bras est autorisé par la rotation des convexités du noeud à l'intérieur de détentes situées aux pointes des cymbales. Les extrémités de chaque bras se terminent dans des éléments cylindriques du type barrettes qui sont parallèles à l'axe charnière principal. Les barrettes se logent dans des gorges cylindriques transversales taillées moulées dans les moulages ou fixées sur ces derniers. Lorsque les moulages sont placés en position fermée centrale avec les bras placés adjacents et en contact, les quatre barrettes sont fixées avec de la colle dans les gorges. Une fois fixées, les deux articulations de la charnière définisent ensemble un axe charnière principal qui se situe à l'arrière et se trouve interadjacent aux moulages. En outre, chaque articulation de charnière peut permettre aux éléments de noeud de sortir des détentes de l'axe et glisser entre les cymbales pour autoriser les mouvements de protrusion et de mastication latérale entre les moulages dentaires.
Patent CA-2267310-C (CA)
Title: Stomach submucosa derived tissue graft
Inventor: BADYLAK STEPHEN F
IPC: A61L27/00
Filed: 1997-12-10
Granted: 2012-09-18
Abstract: A tissue graft composition comprising stomach submucosal tissue delaminated from both the luminal portion of the tunica mucosa and the smooth muscle layers of the muscularis externa of a stomach of a warm blooded vertebrate is described. The graft composition can be or implanted into a host to replace or support damaged or diseased tissues.
Patent CA-2270829-C (CA)
Title: Medico-surgical tubes and methods of manufacture
Inventor: FIELD STEPHEN JAMES
IPC: A61M39/08
Filed: 1999-04-30
Granted: 2008-10-14
Abstract: Epidural catheter with a soft tip are known. In the present invention, a two- layer tube is extruded where the inner layer is stiffer than the outer layer. The inner layer is then removed, such as by machining, from a short length at the tip, which is subsequently end--formed closed and a side opening cut into it so as to form a soft tip.
Patent CA-2275554-C (CA)
Title: Intranasal formulations for treating sexual disorders
Inventor: DUNN PETER JAMES
IPC: C07D487/04
Filed: 1999-06-18
Granted: 2003-06-03
Abstract: Intranasal formulations of sildenafil mesylate for the treatment of male erectile dysfunction or female sexual disorders.
Patent CA-2285041-C (CA)
Title: Cassette for the transformation of yeast
Inventor: BAUER JURGEN
IPC: C12N1/15
Filed: 1999-10-08
Granted: 2010-12-14
Abstract: A DNA cassette (I) for the transformation of yeast not including any exogenous DNA other than the gene of interest is new and comprises at least: (a) a dominant negative marker; (b) two non-exogenous and non-recombinant, directly repeated sequences (DRS) with the genome of the host strain; (c) eventually at least a gene of interest, with the necessary elements for expression in the host cell. A DNA cassette (I) for the transformation of yeast not including any exogenous DNA other than the gene of interest is new and comprises at least: (a) a dominant negative marker; (b) two non-exogenous and non-recombinant, directly repeated sequences (DRS) with the genome of the host strain, the two sequences are positioned in either part of the fragment and contain the dominant positive marker; (c) eventually at least a gene of interest, with the necessary elements for expression in the host cell. Independent claims are also included for the following: (1) a process (II) for the integration of a target gene or the inactivation of a gene in the yeast comprising: (a) transforming the yeast with the help of a DNA construct comprising (I); (b) selecting the yeast comprising the integrated cassette using the positive marker; (c) then, after culture, the yeast is selected comprising the cassettes that has been excised using DRS in selecting yeast deprived of the negative marker; (2) a process for the transformation of an auxotrophic yeast with a plasmid shuttle to obtain expression of an elevated number of copies of at least a gene of interest comprising: (i) transforming the yeast with a plasmid shuttle; (ii) selecting on minimal medium allowing for the induction of the negative marker, the cells not comprising the plasmids in which the part corresponding to Escherichia coli fragments and to the negative marker has been excised; and (3) yeast transformed using (I) obtained by (II) and only contain the DNA of the yeast with the eventual exception of some of the gene(s) coding for a protein of interest and non-coding DRS sequences.
Patent CA-2286281-C (CA)
Inventor: MANGANIELLO FRANCIS X
IPC: B65D47/22
Filed: 1998-04-13
Granted: 2007-08-21
Abstract: A straw assembly (10) has a flexible first segment (16) with at least one longitudinal glide ridge (24) extending outwardly from a drinking end (38). The first segment (16) has a retaining shoulder (18) at a fixed distance from the drinking end (38) and an orienting finger (22) extending from the retaining shoulder (18) to fit in a recess (3 4) on a lid (28) to hold the straw assembly (10) in position so that the longitudinal glide ridges (24) face the sealing cap (36).
Patent CA-2287723-C (CA)
Inventor: MARKHAM JOSEPH P
IPC: A01K15/02
Filed: 1998-06-03
Granted: 2001-02-06
Abstract: A floatable pet toy including a hollow deformable body with a buoyant material, such as a closed cell foam, inside of the body. The buoyant material increases the pet toy's buoyancy and resistance to deformation for durability.  A rope may be attached to the body. In a second embodiment, the body may be elongated, made from elastomeric material, and substantially filled with a closed cell foam insert. This insert has a rope running longitudinally through its center and through an opening in a second end of the body. In a further embodiment, the body may be made from a flexible material, such as canvas or plastic. In a still further embodiment, the buoyant material may be injected into a sealed hollow deformable body for increased buoyancy and durability.
Patent CA-2288241-C (CA)
Title: Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation
Inventor: MAFFRAND JEAN-PIERRE
IPC: A61K31/4545
Filed: 1998-04-17
Granted: 2006-10-03
Abstract: L'invention concerne l'utilisation de dérivés de tétrahydropyridine de formule (I) dans laquelle: R1 représente un halogène ou un groupe CF3, (C1-C4)alkyle ou (C1-C4)alcoxy; Y représente un atome d'azote ou un groupe CH; Z' et Z" représentent chacun l'hydrogène ou un groupe (C1-C3)alkyle, ou bien l'un représente l'hydrogène et l'autre un groupe hydroxy, ou encore les deux, ensemble, représentent un groupe oxo; Z représente: un radical phényle; un radical phényle monosubstitué par un substituant X, X étant: (a) un groupe (C1-C6)alkyle, (C1-C6)alcoxy, (C3-C7)carboxyalkyle, (C1-C4)alcoxycarbonyl(C1-C6)alkyle, (C3-C7)carboxyalcoxy ou (C1-C4)-alcoxycarbonyl(C1-C6)alcoxy; (b) un groupe choisi parmi un (C3-C7)cycloalkyle, (C3-C7)cycloalkyloxy, (C3-C7)cycloalkylméthyle, (C3-C7)cycloalkylamino et cyclohexényle, ledit groupe pouvant être substitué par un halogène, hydroxy, (C1-C4)alcoxy, carboxy, (C1-C4)alcoxycarbonyle, amino, mono- ou di-(C1-C4)alkylamino; ou (c) un groupe choisi parmi un phényle, phénoxy, phénylamino, N-(C1-C3)alkylphénylamino, phénylméthyle, phényléthyle, phényléthyle, phénylcarbonyle, phénylthio, phénylsulfonyle, phénylsulfinyle ou styryle, ledit groupe pouvant être mono- ou polysubstitué sur le group phényle par un halogène, CF3, (C1-C4)alkyle, (C1-C4)alcoxy, cyano, amino, mono- ou di-(C1-C4)alkylamino, (C1-C4)acylamino, carboxy, (C1-C4)alcoxycarbonyle, aminocarbonyle, mono- ou di-(C1-C4)alkylaminocarbonyle, amino(C1-C4)alkyle, hydroxy(C1-C4)alkyle ou halogéno(C1-C4)alkyle; un radical phényle disubstitué par un substituant R2, R2 étant un halogène ou un groupe hydroxy, méthyle, éthyle, (C3-C6)alkyle, (C1-C4)alcoxy ou trifluorométhyle et par un substituant X, X étant tel que défini ci-dessus; un radical 1-naphtyle ou 2-naphtyle; un radical 1-naphtyle ou 2-naphtyle, substitué dans les positions 5, 6, 7 et/ou 8 par un ou deux groupes hydroxyle, un ou deux groupes (C1-C4) alcoxy, ou un groupe 6,7-méthylènedioxy; ou bien Z" est l'hydrogène et Z et Z' représentent, chacun indépendamment, un groupe phényle non substitué ou mono-, di- ou trisubstitué; ou d'un de ses sels et solvates pharmaceutiquement acceptables, pour la préparation de compositions pharmaceutiques destinées à combattre les maladies entraînant une démyélinisation.
Patent CA-2291830-C (CA)
Title: Drinking flask
Inventor: THOMPSON CHRISTOPHER MARK FRAN
IPC: A47G19/22
Filed: 1998-05-20
Granted: 2006-05-09
Abstract: A drinking vessel comprises a body part (10) to receive a drinks liquid, a lid (30) to seal the top of the body part, a liquid outlet passage (50, 52) extending down to a lower region of the interior space of the body part, and an air intake passage (54) also extending down to the lower region of the interior space of the body part. As the user draws liquid out of the vessel through the liquid outlet passage (50, 52), replacement air enters through the air intake passage (54) and then bubbles upwardly through the liquid within the vessel.
Patent CA-2292535-C (CA)
Title: Method and apparatus for improving classroom amplification systems and other rf-type amplification systems
Inventor: FRANKLIN DAVID
IPC: H04H20/76
Filed: 1998-06-02
Granted: 2006-06-06
Abstract: An RF-type amplification system, such as a classroom amplification system, employs technology adapted from a cordless telephone system to overcome interference. The amplification system includes a portable remote unit (87) and a base unit (82). Remote unit (87) includes: a microphone (151) for detecting a voice and generating corresponding voice signals; a transmitter (160, 161) which generates RF signals containing the voice signals as well as control signals provided by the central processing unit (179) of remote unit (87), and an antenna (168) for transmitting the RF signals and for receiving RF signals from base unit (82). Base unit (82) includes an antenna (107) which receives the RF signals transmitted by the remote unit and a receiver (108, 114, 115, 117) which detects the RF signals and separates the RF signals into the voice signals and control signals. The control signals are identified by a code detector (118) of base unit (82) and evaluated by a CPU (130). If the values of the control signals are as expected, the voice signals are processed through a speech network (121) and provided at a communications interface to an audio power amplifier (147) which amplifies the voice signals and supplies the voice signals to speakers which audibly project the voice signals as sound. Base unit (82) further includes a transmitter (133, 135) for generating RF signals containing control signals but no voice signals, that are transmitted to remote unit (87), thereby effecting one-way transmission of voice signals and two-way transmission of control signals between remote unit (87) and base unit (82).
Patent CA-2295420-C (CA)
Inventor: GARRETT CHARLES RON
IPC: F16G11/14
Filed: 2000-01-14
Granted: 2009-04-07
Abstract: A fitting for a synthetic web sling. In one preferred embodiment, the fitting includes a spool for receiving the synthetic web sling. A hook is opposed to the spool, the hook having a width and having a saddle for receiving the synthetic web sling therein. The saddle includes an arcuate surface with an expanded diameter larger than said width of said hook. The saddle also includes a central raised portion. A pair of opposed frusto- conical bumpers are axially aligned with the saddle to laterally align the web sling on the saddle.
Patent CA-2303432-C (CA)
Inventor: SANKARAM MANTRIPRAGADA
IPC: A61K47/14
Filed: 1998-09-08
Granted: 2008-02-12
Abstract: Disclosed is a method for making liposomes, for example multivesicular liposomes (MVLs), containing one or more biologically active agents, wherein the loading of the active agents into the liposomes is modulated by adjusting the osmolarity of the aqueous component into which the agents are dissolved prior to encapsulation. To increase the loadi ng of the active agent, the osmolarity of the aqueous component is reduced, and to decrease the loading of the active agent, the osmolarity of the aqueous component is increased. In the making of MVLs, the process involves dissolving the active agent and an optimal osmotic excipient in a first aqueous component encapsulated within the liposomes. For any given concentration of drug, the osmolarity of the first aqueous component can be adjusted by increasing or decreasing the concentration or molecular weight of the osmotic excipients used therein . The rate of release of the active agent into the surrounding environment in which the liposomes are introduced can be simultaneously controlled by incorporating into the lipid component used in the formulation at least one long chain amphipathic lipid. For example the amphipathic lipid can have from about 13 to about 28 carbons for example, from about 18 to about 22 carbons, in its carbon chain. Use of the long chain amphipathic lipid in the lipid component is particularly helpful in controlling the release rate and encapsulation efficiency for high drug load formulations.
Patent CA-2305822-C (CA)
Title: Expanded structures and method for forming
Inventor: MAKAR JOSEPH
IPC: B44C3/02
Filed: 2000-04-14
Granted: 2003-07-01
Abstract: Expanded structures are formed by cutting a series of concentric rings or sections from a single block or sheet of solid material. The "rings" need not be circular, but may be any regular or irregular geometric or other shape as desired, so long as they are substantially concentric with one another. The cuts are made so that they angle outwardly from the upper to the lower surface of the block or sheet, and pass completely through the sheet or block.      This provides a series of concentric sections, with each section having a lower, outer periphery which is at least slightly larger than the upper, inner periphery of the next larger adjacent section. This allows each section to be stacked atop a larger adjacent section, with the lower outer edge surface of each smaller section resting upon the upper inner edge surface of the larger section immediately therebelow. Alternatively, the tapered outer and inner walls or faces of adjacent sections may be wedged together, with an adjacent inner section protruding somewhat from the plane of its adjacent outer section. Such structures may be formed in virtually any practicable size, from utility sheds including door and window openings formed therein, to smaller household containers, works of art, etc. as desired. The structures may be made permanent by coating with a suitable material (e. g., glass fiber and resin, etc.) if so desired.      Different colors of materials may also be assembled together, to produce structures having alternating bands of colors therein.
Patent CA-2306211-C (CA)
Title: Methods for the rapid detection of viable bacteria
Inventor: THACKER JAMES D
IPC: G01N33/543
Filed: 1998-09-04
Granted: 2008-06-17
Abstract: The invention relates to methods for the rapid detection, including quantitative detection, of actively respiring microorganisms. One embodiment comprises the steps of amplifying the presence of microorganisms utilizing microbial enzymatic conversion of tetrazolium salts to formazan products, detecting the presence of formazan product utilizing specific antibodies raised to formazans and amplifying the presence of the primary antibody with a secondary antibody conjugated to a detectable marker. Another embodiment of the invention comprises the steps of amplifying the microorganisms utilizing microbial enzymatic conversion of tetrazolium salts to formazan products, capturing digested microbial cell fragments with immobilized primary antibodies specific to the formazans and amplifying the presence of captured cell fragments with reporter antibodies prepared from the primary antibodies conjugated to a detectable marker. Another embodiment of the invention comprises the steps of amplifying microorganisms utilizing microbial enzymatic conversion of tetrazolium salt to formazan products, capturing digested microbial cell fragments on primary antibodies immobilized onto a solid sensor support and detecting the presence of captured cell fragments by the measurement of a change in either the physical, chemical electrical or optical properties of the sensor material.
Patent CA-2309225-C (CA)
Inventor: SUNDKVIST JAN-ERIC
IPC: C22B3/18
Filed: 2000-05-24
Granted: 2004-09-14
Abstract: A method for winning the valuable metal content of a leaching solution acidified with sulphuric acid, by solvent extraction and electrowinning and a following final product winning stage, for instance an electrowinning stage, wherein the pH of the leaching solution is raised successively to precipitate out the iron and arsenic present in a first precipitation stage, removing said first precipitate, and precipitating the valuable metal content of the leaching solution substantially totally in a following precipitation stage. The resultant precipitate containing valuable metal and gypsum is removed and leached in an acid environment to re-dissolve the valuable metal content, and the thus formed acid solution and its metal content are delivered to a solvent extraction circuit in which the metal content is converted to a substantial degree to an acid electrolyte from which metal or some other end product is won. The acid solution deplete of valuable metal and deriving from the solvent extraction stage can be returned to the stage in which the valuable metal content is re-dissolved and, when electrowinning is used for winning the end product, electrolyte deplete of valuable metal can be cycled from the electrowinning stage to the solvent extraction circuit.
Patent CA-2312335-C (CA)
Title: Method of making cellulosic composite articles
Inventor: RUFFIN THOMAS M
IPC: B27N3/08
Filed: 1998-12-04
Granted: 2005-02-22
Abstract: A method of forming a consolidated wood product is disclosed wherein zinc borate and resin are mixed with cellulosic material to form treated cellulosic material, followed by applying heat and pressure to form a consolidated cellulosic product. A consolidated product comprises zinc borate, resin, and cellulosic material, wherein the zinc borate is distributed throughout the lignocellulosic material. A steam injection process is also disclosed.
Patent CA-2322616-C (CA)
Title: A process for isolating and purifying viruses, soluble proteins and peptides from plant sources
Inventor: GARGER STEPHEN J
IPC: C07K16/00
Filed: 1999-03-09
Granted: 2008-05-27
Abstract: The present invention features a method for isolating and purifying viruses, proteins and peptides of interest from a plant host which is applicable on a large scale. Moreover, the present invention provides a more efficient method for isolating viruses, proteins and peptides of interest than those methods described in the prior art. In general, the present method of isolating viruses, proteins and peptides of interest comprises the steps of homogenizing a plant to produce a green juice, adjusting the pH of and heating the green juice, separating the target species, either virus or protein/peptide, from other components of the green juice by one or more cycles of centrifugation, resuspension, and ultrafiltration, and finally purifying virus particles by such procedure as PEG-precipitation or purifying proteins and peptides by such procedures as chromatography and/or salt precipitation.
Patent CA-2325147-C (CA)
Inventor: GROUSE CHARLES J
IPC: H05K7/14
Filed: 2000-11-06
Granted: 2003-08-19
Abstract: A back up power supply for avionics equipment that can be installed in existing avionics equipment trays without having to rewire the aircraft. According to a preferred embodiment of the invention (described for illustrative purposes in the context of providing a power supply back up for a cockpit voice recorder (CVR)), the power supply/CVR combination is retrofit in an existing CVR rack. The power supply is, according to the aforementioned preferred embodiment, modular; removable/replaceable; and is "independent" relative to the main aircraft power source and wiring. The power supply/CVR combination is designed to fit into a conventional CVR tray; and the CVR is designed to fit into the modular power supply. Furthermore, according to a preferred embodiment, the power supply is "plug compatible" with the existing electrical connector in the CVR tray and includes circuitry which allows both the power supply and CVR to be tested using the existing CVR test button in the cockpit; and to report faults from either unit using existing aircraft wiring. Moreover, the power supply includes circuitry which automatically electrically disconnects it from the CVR and exposed pins when the power supply is removed from the CVR tray. The CVR and power supply of the preferred embodiment of the invention being modular are easy to install, require no cables, occupy approximately the same space previously occupied by the existing CVR, and have substantially the same center of gravity as the existing CVR. Integrated avionics/back up power supply units are also contemplated by the invention where the units are designed to fit into existing equipment trays to eliminate and/or minimize the need for re-wiring the aircraft.