baber/WOPTO huggingface dataset:
Patent CA-2335941-C (CA)
Inventor: MAURER BARRY JAMES
IPC: A61K45/00
Filed: 1999-06-28
Granted: 2011-03-22
Abstract: La présente invention concerne un traitement de trouble hyperproliférant, chez un sujet le requérant, qui comprend l'administration audit sujet, d'une quantité efficace d'un traitement combiné composé: (a) d'un rétinoïde générateur de céramide tel que le fenretinide ou un de ses sels acceptables sur le plan pharmaceutique; et (b) au moins d'un (et dans certaines réalisations au moins de deux) inhibiteur de dégradation de céramide tel que des composés choisi parmi (i) des inhibiteurs de synthèse de glucosylcéramide, (ii) d'inhibiteurs de synthèse de sphingosine-1-phosphate, et (iii) d'inhibiteurs de protéine kinase C. Un inhibiteur préféré de synthèse de céramide glucosyle est le 1-phényl-2-palmitoylamino-3-morpholino-1-propanol. Un inhibiteur préféré de synthèse de sphingosine-1-phosphate est le D-érythro-N,N-diméthylsphingosine. Un inhibiteur préféré de protéine kinase C est le L-thréo-dihydrosphingosine.
Patent CA-2341537-C (CA)
Title: Device and method for stripping a cable
Inventor: SORKIN FELIX L
IPC: H02G1/12
Filed: 1999-08-20
Granted: 2008-11-18
Abstract: A device (10) for stripping a cable having a body (12) with a channel (14) extending therethrough so as to open at a narrow end (16) of the body so as to have a blade with a cutting edge (18) extending upwardl y into the channel. The blade extends at an angle of between 70 degrees and 89 degrees with respect to the longitudinal axis. The body includes a handle (13) and a cutting head (15) affixed to the end of the handle. The channel (14) extends through the handle and the cutting head. The handle is compressable so as to reduce the diameter of the channel upon the application of a squeezing force onto the handle. Th e handle has projections (37) extending into the channel. The cutting head has a notch (49) extending along an outer surface of the cuttin g head. The knife is received within the notch. The knife is formed of a stamped metal material.
Patent CA-2342312-C (CA)
Title: Ajustable mechanism with locking brake
Inventor: RODRIGUES ORLANDO
IPC: F21V21/30
Filed: 2001-03-27
Granted: 2009-12-08
Abstract: The present invention provides a support assembly for a lighting fixture that allows for the adjustment and positioning of a lamp about both a horizontal and a vertical axis using only one locking mechanism. The support assembly includes a first support member that is pivotably attached to a second support member. The support assembly also includes a cylindrical sleeve to which the second support member is adjustably engaged. Both support members include at least one leg extending therefrom. The locking mechanism includes a pivoting brake shoe that can engage the cylindrical sleeve so as to secure the lamp into position about a vertical axis. The locking mechanism also includes a thumbscrew that is housed within a slot defined within a leg of the first support member, and that engages both the brake shoe and a leg on the second support member.
Patent CA-2348956-C (CA)
Inventor: STAUSS HANS JOSEF
IPC: C12N5/09
Filed: 1999-11-02
Granted: 2012-05-22
Abstract: A peptide comprising the amino acid sequence RMFPNAPYL or a portion or variant thereof provided that the peptide is not intact human WT-I polypeptide or a peptide comprising the amino acid sequence CMTWNQMNL or a portion or variant thereof provided that the peptide is not intact human WT-I polypeptide or a peptide comprising the amino acid sequence HLMPFPGPLL or a portion or variant thereof provided that the peptide is not intact human gata-1 polypeptide, and polynucleotides encoding these peptides. The peptides and polynucleotides are useful as cancer vaccines.
Patent CA-2349007-C (CA)
Inventor: TIEBEN JAMES B
IPC: F01C21/02
Filed: 2000-07-26
Granted: 2005-03-22
Abstract: A hydraulic pump includes a pump mechanism (12) having a driven shaft (16). The driven shaft (16) is connected to an input shaft (50) by a flexible coupling such as a splined connection. A housing (30) extends completely around the driven shaft (16), and a high-pressure seal (74) is disposed between the housing (30) and the input shaft (50). A thrust bearing (72) carries hydraulic axial forces on the input shaft (50) to the housing (30). This arrangement provides balanced hydraulic forces on both ends (18, 20) of the driven shaft (16), thereby reducing friction and wear.
Patent CA-2350834-C (CA)
Title: N-terminally truncated her-2/neu protein as a cancer prognostic indicator
Inventor: CLINTON GAIL
IPC: G01N33/574
Filed: 1999-11-13
Granted: 2008-10-07
Abstract: There is disclosed an initial identification of an N-terminally truncated HER-2/neu product. This product is a 95kDa polypeptide having in vitro kinase activity (as determined by western blotting). Moreover, immunoprecipitations using domain specific antibodies was able to utilize this specific polypeptide from intracellular fragments as a diagnostic and prognostic indicator of adenomacarcinomas without the severe dilution effects encountered by measuring ECD.
Patent CA-2354679-C (CA)
Inventor: MASON HENRY H JR
IPC: H02H1/00
Filed: 2001-08-02
Granted: 2014-03-25
Abstract: An arc fault current interrupting (AFCI) circuit breaker (10) includes a pair of electrical contacts (20, 34) for stopping the flow of electrical current in a protected portion of the distribution circuit. A low pass filter (102) is configured to receive a signal indicative of a voltage across a resistance (106) in the distribution circuit. The low pass filter (102) amplifies the signal and provides the signal to an arc fault detection circuit. The low pass filter (102) includes an input resistance (106) and a feedback resistance (108). In one embodiment of the invention, the input resistance (106) has a positive temperature coefficient. In another embodiment, the feedback resistance (108) has a negative temperature coefficient. In yet another embodiment, the input resistance (106) has a positive temperature coefficient and the feedback resistance (108) has a negative temperature coefficient. In any of the embodiments, when temperature decreases, the gain provided by the temperature compensation circuit (100) increases due to the temperature coefficients of the input and/or feedback resistors ((106, 108). As a result, the arc fault detection circuitry will maintain a constant sensitivity to arc faults throughout the entire operating temperature range of the AFCI circuit breaker (10).
Patent CA-2354839-C (CA)
Title: Frame and seat support for a riding lawnmower
Inventor: DEWEESE ROBERT M
IPC: A01D67/00
Filed: 2001-08-09
Granted: 2004-06-15
Abstract: A frame channel is provided for the mounting of an engine of a rear engine riding lawn mower. A platform is secured to the frame channel, the platform includes a portion which overlays the engine and which includes an opening therein. A  seat-supporting hood normally overlays the opening. The hood is pivotally mounted to the platform whereby when the hood is pivoted to an open position to expose the platform opening, access to the engine is obtained.
Patent CA-2355716-C (CA)
Title: Benzisoxazoles and phenones as .alpha.2-antagonists
Inventor: KENNIS LUDO EDMOND JOSEPHINE
IPC: A61P25/24
Filed: 1999-12-14
Granted: 2010-05-18
Abstract: The present invention concerns compounds of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Alk is C5-12alkanediyl; n is 1 or 2; p is 1 and q is 2; or p is 2 and q is 1; X is -O-, -S-, -S(=O)-, -S(=O)2- or NR2; each R1 is independently hydrogen, halogen, C1-6alkyl, nitro, hydroxy or C1-4alkyloxy; R2 is hydrogen, C1-6alkyl, aryl or C1-6alkyl substituted with aryl; aryl is phenyl or phenyl substituted with a halogen or C1-6alkyl; D is an optionally substituted benzophenone or 3-benzisoxazolyl; having central .alpha.2-adrenoceptor antagonist activity. It further relates to their preparation, pharmaceutical use and compositions.
Patent CA-2363086-C (CA)
Inventor: KAULE WITTICH
IPC: B42D25/328
Filed: 2000-02-22
Granted: 2009-12-08
Abstract: The invention relates to a document of value such as a paper of value or ID card with a security element having an optically variable material. Said opticall y variable material conveys different color effects at different viewing angles. Additionally, the security element has at least one machine-readable feature substance that do es not impair the visually visible optically variable effect of the optically variable material.
Patent CA-2365775-C (CA)
Inventor: KOIVUKUNNAS PEKKA
IPC: D21G1/02
Filed: 1994-11-23
Granted: 2004-09-28
Abstract: The invention concerns a calender for the calendering of a paper or of an equivalent web material. The calender comprises a frame (11,11a), a variable-crown upper roll (13,13a), a variable-crown lower roll (14,14a) and two or more intermediate rolls (15...22,15a...22a) fitted between the upper (13,13a) and lower (14,14a) rolls. The upper, lower and intermediate rolls are arranged on the frame (11,11a) of the calender as a stack of rolls (12,12a) and being in nip contact with one another to form calendering nips (N1...N9) between the rolls. Hard- and soft-faced rolls are used as the intermediate rolls in which the form of the natural deflection line produced by their own gravity is substantially equal. The nip loads produced by the masses of the intermediate rolls and of the auxiliary equipment related to them are relieved and at least one of the intermediate rolls (15...22,15a...22a) is a cooled roll which is provided with a resilient polymer coating.
Patent CA-2376573-C (CA)
Inventor: BAULIER DOMINIQUE
IPC: B21D43/10
Filed: 2002-03-13
Granted: 2007-08-28
Abstract: A workpiece loader/unloader system for an industrial machine, such as a hemmer, is disclosed. The system includes a single pocket shuttle movable between an extended position in which the shuttle overlies a work station on the industrial machine, and a retracted position in which the shuttle is laterally spaced from the work station. A gripper on the shuttle selectively engages and supports the workpiece after the workpiece has been machined at the work station. A loader manipulator is movable between a preload position in which the loader supports an unmachined workpiece at a position laterally spaced from the work station, and a load position in which the loader manipulator overlies the work station. An actuator moves the loader manipulator between the preload and load position. Furthermore, the loader manipulator mechanically engages the shuttle and simultaneously moves the shuttle from its extended position and to its retracted position as the loader manipulator moves from its preload and to its load position. A passive system, such as a spring, returns the shuttle from its retracted and to its extended position.
Patent CA-2383586-C (CA)
Inventor: WORMAN DONALD D
IPC: C07C21/06
Filed: 2000-08-31
Granted: 2006-03-14
Abstract: A heater includes a radiant section having a wall and a roof, the roof having a longitudinal opening. A radiant heat exchange tube is disposed in the radiant section, and the tube has an inlet and outlet through which a process fluid can be carried respectively into and out of the radiant section. The tube between the inlet and outlet is arranged in generally horizontal tube lengths. A plurality of burners is provided, at least two of the burners being disposed on opposing sides of the tube. A plurality of tube supports is releasably positioned at longitudinal intervals along the tube lengths and define tube seats on which the tube lengths rest. The tube and tube supports are liftable as a unit through the longitudinal opening of the roof of the radiant section.
Patent CA-2387289-C (CA)
Title: Packet communication method and proposal node
Inventor: MURAKAMI HOMARE
IPC: H04W80/06
Filed: 2002-05-23
Granted: 2010-12-21
Abstract: Upon recovery of communication, this recovery is detected by communication recover detector and then optimal times duplicated pseudo acknowledgements calculated by arithmetic unit are transmitted from ACK transmitter. During normal state, advertisement is made in small value of advertised receive window size and immediately after recovery state, advertisement is made in expanded window size.
Patent CA-2393009-C (CA)
Inventor: TARSA ERIC J
IPC: H01L33/14
Filed: 2000-11-22
Granted: 2011-10-18
Abstract: An LED with improved current spreading structures that provide enhanced current injection into the LED's active layer (14), improving its power and luminous flux. The current spreading structures can be used in LEDs larger than conventional LEDs while maintaining the enhanced current injection. The invention is particularly applicable to LEDs having insulating substrates (12) but can also reduce the series resistance of LEDs having conductive substrates. The improved structures comprise conductive fingers (20a, 20b, 22) that form cooperating conductive paths that ensure that current spreads from the contacts (19, 21), into the fingers (20a, 20b, 22) and uniformly spreads through the oppositely doped layers (15, 16). The current then spreads to the active layer (14) to uniformly inject electrons and holes throughout the active layer (14), which recombine to emit light.
Patent CA-2393603-C (CA)
Inventor: RICHARDS AMY C
IPC: A61K47/30
Filed: 2000-12-01
Granted: 2010-09-21
Abstract: Methods of manufacturing microchip devices are provided for controlled release of molecules, such as drugs. Methods include compression molding and casting, alone or in combination with microfabrication techniques. In preferred embodiments, devices are made by (1) filling a die with a polymer powder; (2) compressing the powder to form a polymer preform; (3) thermal compression molding the preform to form a substrate in a mold having a plurality of protrusions that form reservoirs in the substrate; and (4) filling the reservoirs with a release system comprising the molecules to be released. Alternatively, ceramic devices are formed by casting the substrate from a ceramic powder or a slurry using a mold having protrusions that form reservoirs in the substrate. Control over the release rate and time of the molecules from the reservoirs of the microchip device is provided by incorporating release systems and/or reservoir caps.
Patent CA-2395209-C (CA)
Title: Pack agent in a sheet form
Inventor: HAMAMOTO HIDETOSHI
IPC: A61K8/81
Filed: 2001-11-07
Granted: 2011-10-18
Abstract: The present invention is directed to a sheet like pack effective for prevention and improvement of small wrinkles on skin, comprising a water soluble high molecular compound, water and abiquinone 10 as an active ingredient. These components are contained in a base.
Patent CA-2396291-C (CA)
Inventor: ROCK DOUGLAS LAWRENCE
IPC: E21B43/30
Filed: 2002-07-31
Granted: 2008-06-03
Abstract: A method is disclosed for drilling a borehole through a production zone underlying an overburden of various earth formations. The method includes drilling the borehole through the overburden with at least one drill bit adapted to optimize at least one drilling performance parameter, and then drilling the borehole through at least part of the production zone with at least one drill bit adapted to optimize at least one production performance parameter.
Patent CA-2396356-C (CA)
Title: Carbon block water filter
Inventor: KUENNEN ROY W
IPC: C02F1/28
Filed: 2001-10-25
Granted: 2005-03-29
Abstract: An activated carbon block filter (10) including a unique bonded carbon mixture. The carbon mixture preferably includes a mean particle diameter in the range of about 60 microns to about 80 microns and a particle size distribution having less than 10 % by weight of particles larger than 140 mesh and less than 10 % by weight of particles smaller than 500 mesh. More preferably, the carbon mixture includes a mean particle diameter in the range of about 65 microns to about 75 microns. Even more preferably, the carbon mixture includes a mean particle diameter of about 70 microns and a particle size distribution having less than 7 % by weight of particles larger than 140 mesh and less than 7.5 % by weight of particles smaller than 500 mesh.
Patent CA-2397810-C (CA)
Inventor: TRUST DONALD BRUCE
IPC: C10G2/00
Filed: 2001-01-18
Granted: 2010-04-27
Abstract: Pendant le déparaffinage catalytique d'hydrocarbures paraffiniques, la réaction de déparaffinage catalytique exothermique est atténuée par la séparation et le refroidissement d'un déparaffinat lourd dont le point d'ébullition initial est d'au moins 800 ·F+, et par son recyclage par un retour dans la zone de déparaffinage sous forme de liquide de refroidissement. Ce déparaffinat lourd réagit très peu, sinon pas du tout, avec l'hydrogène dans la zone de déparaffinage. Ce procédé s'est révélé particulièrement utile pour déparaffiner des hydrocarbures hydro-isomérisés, synthétisés par procédé paraffinique Fischer-Tropsch.
Patent CA-2399314-C (CA)
Inventor: SCHLOSSER KEVIN F
IPC: F16D13/70
Filed: 1995-06-19
Granted: 2004-03-02
Abstract: A friction device includes an adjustment mechanism for adjusting the device in response to wear on a friction surface within the device. The adjustment mechanism includes a first cam ring and a second cam ring adjacent the first cam ring. In one embodiment, the first cam ring is adapted for axial, but non-rotational movement with respect to a cover of the friction device, the cover being secured to a driving member for transmitting torque. The second cam ring is adapted for rotational movement with respect to the cover and the first cam ring. The first cam ring has a plurality of annular ramped surfaces on an axial face of the first cam ring. The second cam ring has a plurality of annular ramped surfaces on an axial face opposing the axial face of the first cam ring. The second cam ring is rotated with respect to the first cam ring such that the ramped surfaces cam against each other to increase the axial displacement of the first cam ring and the second cam ring, whereby the axial displacement is adapted to compensate for wear on a friction surface of a member of the friction device.
Patent CA-2401302-C (CA)
Inventor: MAHE YANNICK
IPC: A23L23/00
Filed: 2001-03-12
Granted: 2009-12-22
Abstract: L'invention concerne un adjuvant pour la cuisine, composé d'une enveloppe à base de graisse solide à température ambiante et d'une garniture aromatique liquide ou pâteuse. L'enveloppe du produit de l'invention fond rapidement au contact d'un aliment chaud ou dans une poêle à frire et possède une bonne résistance mécanique aux manipulations à température ambiante. L'enveloppe comprend entre 40 et 100 % de graisse et entre 0 et 60 % d'additifs de garniture de type polysaccharidique, protéique ou fibreux, ou un mélange de ces derniers. La garniture aqueuse et/ou grasse du produit de l'invention présente une viscosité située entre du miel liquide et un produit à tartiner pâteux. L'invention concerne un procédé de fabrication de cet adjuvant pour la cuisine.
Patent CA-2402768-C (CA)
Inventor: TOIYAMA YOSHIRO
IPC: F16F9/08
Filed: 2002-09-11
Granted: 2006-12-19
Abstract: A hydraulic shock absorber comprises a cylinder (11) with an expandable and contractible piston rod (12), an outer casing (13) disposed on the outside of the cylinder (11), and a reservoir (16) defined between the outer casing and the cylinder. Due to an elastically deformable bladder (14) disposed inside the reservoir, a gas chamber (17) in which gas is sealed is formed between the bladder and the outer casing, and a reservoir chamber (18) communicated with the inside of the cylinder and designed for guiding hydraulic fluid is formed between the bladder and the cylinder. Furthermore, a gas sealing valve (23) for opening and closing a flow conduit (24) communicated with the gas chamber provided to part of the outer casing is provided to a bottom portion (19) of the outer casing, and allowing gas to enter and exit the gas chamber via the gas sealing valve makes it possible to freely adjust the gas pressure in the hydraulic shock absorber from the outside.
Patent CA-2403102-C (CA)
Title: Manganese dry battery
Inventor: OGINO KEIJI
IPC: H01M50/193
Filed: 2001-03-08
Granted: 2008-06-17
Abstract: A manganese dry battery which is stable and has an excellent gas tightness with any type of heat-shrinkable tube. The manganese dry battery comprises an anode zinc can (1), a cathode mixture (2) contained in the can, a separator (14) interposed between the can and the mixture, a carbon rod (3) inserted in the center of the mixture, a gasket (5) sealing the opening of the can and having a hole in the center thereof through which the carbon rod is inserted and a heat-shrinkable tube (6) covering the circumference of the can with the outer periphery of the gasket. The heat-shrinkable tube comprises at least one selected from the group consisting of polystyrene, polypropylene, polyethylene and a copolymer of ethylene and propylene, and a sealant (9) is applied at least between the opening end of the can and the gasket.
Patent CA-2405669-C (CA)
Inventor: PASCOE DAVID MARK
IPC: F04D15/00
Filed: 2001-04-12
Granted: 2009-10-13
Abstract: L'invention concerne une pompe à eau à capacité variable comprenant un boîtier présentant une turbine montée sur un arbre rotatif. Cette turbine comprend plusieurs ailettes couplées de façon pivotante entre la chemise supérieure et la chemise inférieure et couplées de façon fonctionnelle à un plateau de tangage. A mesure que la vitesse de la pompe augmente en réponse à l'augmentation de la vitesse du moteur, le plateau de tangage commande la rotation des ailettes de la turbine autour d'un rivet fixe à partir d'une position de plateau de tangage maximale, vers une position de plateau de tangage minimale, abaissant ainsi la sortie de la pompe en fonction des normes de refroidissement du moteur.
Patent CA-2408538-C (CA)
Title: Fuel cell assembly with heater wire provided on a grid frame of an electrolyte layer
Inventor: KUBOTA TADAHIRO
IPC: H01M8/24
Filed: 2001-05-02
Granted: 2008-05-20
Abstract: In a fuel cell assembly comprising at least one cell including an electrolyt e layer, a pair of gas diffusion electrode layers interposing the electrolyte layer between them, and a pair of flow distribution plates for defining passages for fuel and oxidizer gases that contact the gas diffusion electrode layers, the electrolyte layer comprises a grid frame provided with a multitude of through holes, and electrolyte retained in each through hole, heater wire being disposed in a grid bar of the frame so that the entire catalyst and electrolyte may be heated up to a desired temperature suitable for the reaction, instead of being heated only locally, in a short period of time, a nd the desired output can be obtained in a short period of time following the start-up.</SD OAB>
Patent CA-2409476-C (CA)
Inventor: SMITH FRANK C
IPC: B27L7/00
Filed: 2002-10-23
Granted: 2006-08-29
Abstract: A method and apparatus is taught for engaging, positioning, and splitting logs. A wedge section of a skid steer loader coupling device is received in a lip section of a log splitting system coupling device. A body section of the skid steer loader coupling device is urged into a flush position with a body section of a log splitting system coupling device. Levers on the skid steer loader coupling device are actuated from a first position to a second position so that pin devices coupled to the levers move from a disengaged to an engaged position with respect to apertures in the log splitting system coupling device. Hoses are coupled at a first end of the log splitting system and at a second end of the skid steer loader. The skid steer loader is maneuvered proximate a first one of the logs to be engaged from above the first one of the logs. A pushing mechanism is actuated to push a first end of the first one of the logs with a pushing device a predetermined amount so that a second end of the first one of the logs interacts with a cutting device sufficiently to engage the first one of the logs. The skid steer loader is maneuvered to a predetermined location. Finally, said pushing mechanism is actuated until said engaged log is split at said predetermined location.