baber/WOPTO huggingface dataset:
Patent IL-107819-A0 (IL)
Title: 6,7-Modified paclitaxels
IPC: A61K31/341
Filed: 1993-12-01
Abstract: The present invention provides paclitaxel derivatives of formula I   <CHEM>  in which   R<1> is   -COR<z> in which R<z> is RO- or R; R<2> is   C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, or a radical of the formula -W-R<x> in which W is a bond, C2-6 alkenediyl, or -(CH2)t-, in which t is one to six; and R<x> is naphthyl, phenyl, or heteroaryl, and furthermore R<x> can be optionally substituted with one to three same or different C1-6 alkyl, C1-6 alkoxy, halogen or -CF3 groups; R<a> is   -OCOR, H, OH, -OR, -OSO2R, -OCONR<o>R, -OCONHR, -OCOO(CH2)tR, or -OCOOR; R<b> and R<c>   are both hydroxy or together form a bond with the carbon atoms to which they are attached; and R and R<o>   are independently C1-6 alkyl, C2-6 alkenyl, C3-6 cycloalkyl, C2-6 alkynyl, or phenyl, optionally substituted with one to three same or different C1-6 alkyl, C1-6 alkoxy, halogen or -CF3 groups.   Also provided by this invention are pharmaceutical formulations (compositions) and a method of treating mammalian tumors with a compound of formula I.
Patent IL-109605-A0 (IL)
Title: Nucleosides and oligonucleotides having 2'-ether groups, their preparation and their use
IPC: C07H19/14
Filed: 1994-05-10
Abstract: Compounds of the formula <IMAGE> in which R1 and R2 are, independently of one another, hydrogen or a protective group, or R1 has these meanings and R2 is a radical forming a phosphorus-containing nucleotide bridging group; B is a purine or pyrimidine residue or an analogue thereof; and R3 is a radical of the formula Ia, Ib or Ic <IMAGE> in which R4 is hydrogen, C1-C21-alkyl, C2-C21-alkenyl, C2-C21- alkynyl or -C(=O)-alkyl; R5 is hydrogen, C1-C10-alkyl, -CH2-O-R6 or a radical of the formula Ib; R6 is hydrogen, C1-C22-alkyl, C3-C21-alkenyl, partially or completely fluorine-substituted C1-C10-alkyl or -[(CH2)2-O]m-R7; R 7 is hydrogen or C1-C21-alkyl; Z is -(CH2)p- or -(CH2-CH-O)q-CH2 CH2-, where Z can in the case of -CH2- be unsubstituted or substituted by one or more C1-C10-alkyl, C5-C6-cycloalkyl or unsubstituted or C1-C4-alkyl-substituted phenyl, independently of one another; n is a number from 1 to 12; m is a number from 1 to 4; p is a number from 1 to 10; and q is a number from 1 to 4, are described.
Patent IL-113611-A0 (IL)
Title: A device for the release of subtances from pressure-sensitive hot-melt adhesives
IPC: A61L15/44
Filed: 1995-05-03
Abstract: A device for the release of substances from pressure sensitive hot-melt adhesives with a uniform or non-uniform distribution of said substances is characterized by the fact that the pressure sensitive hot-melt adhesive is hydrophilic and comprises at least one water-soluble, or at least water-swellable, polymer, at least one water-soluble, meltable adhesive resin, as well as substance to be released.
Patent IL-115081-A0 (IL)
Title: Compositions containing phosphosulfonate herbicides and dichloroamides and their use
IPC: A01N57/20
Filed: 1995-08-28
Abstract: This invention pertains to compositions comprising:   (i) one or more herbicidal phosphosulfonates, having the general formula <CHEM>  wherein Y is an optionally substituted phenyl, naphthyl, benzyl, (C5-C8)cycloalkyl, 5-membered heteroaromatic ring, 6-membered heteraromatic ring, fused 5,6-membered heteroaromatic ring, or fused 6,6-membered heteroaromatic ring;     X is an oxygen or a sulfur atom; and R<1> and R<2> are each independently selected from alkyl, alkoxy, alkylthio, alkenyloxy, alkynyloxy, haloalkoxy, cyanoalkoxy, alkoxyalkoxy, cycloalkyloxy, cycloalkylalkoxy, alkylideneiminooxy, chloro, and amino with one or two substituents selected from alkyl, alkenyl and phenyl, provided that R<1> may additionally be selected from phenyl or phenoxy, and provided that when or R<1> and R<2> are both alkoxy, R<1> and R<2> can together with the phosphorus atom form a 6-membered oxygen-containing ring;   (ii) dichloroacetamide safeners having the general formula <CHEM>  wherein R<a> and R<b> are each independently selected from alkyl, alkenyl, or alkyl or alkenyl substituted with halo, or R<a> and R<b> together with the nitrogen atom to which they are attached form a 5- or 6-membered substituted heterocyclic ring; and   (iii) an agronomically acceptable carrier.   The present invention also pertains to the use of these compositions as selective herbicides.
Patent IL-127847-A0 (IL)
Title: Multivalent DTP-polio vaccines
IPC: A61K31/00
Filed: 1997-07-02
Abstract: A multi-component vaccine composition is described comprising acellular pertussis vaccine components, diphtheria toxoid, tetanus toxoid and inactivated poliovirus. The composition also may contain a conjugate of a capsular polysaccharide of  Haemophilus influenzae  type b and tetanus toxoid or diphteria toxoid, which may be reconstituted from a lyophilized state by the other components of the vaccine. The administration of the multiple component vaccine results in no diminution in the immunogenicity of any component as a result of interference by other components of the vaccine.
Patent IL-139914-A0 (IL)
Title: Use of indigoid bisindole derivatives for the manufacture of a medicament to inhibit cyclin dependent kinases
IPC: A61P25/28
Filed: 1999-05-26
Abstract: The present invention relates to the use of indigoid bisindole derivatives for the manufacture of a medicament for inhibiting cyclin dependent kinases, particularly CDK 1, CDK 2, CDK 4 and CDK 5, more particularly ATP:Proteinphosphotransferase p34<cdc2> (CDK1).
Patent IL-143805-A0 (IL)
Title: Combination therapy of radiation and a cox-2 inhibitor for the treatment of neoplasia
IPC: A61K31/4439
Filed: 1999-12-22
Abstract: The present invention provides methods to treat or prevent neoplasia disorders in a mammal using a combination of radiation therapy and a cyclooxygenase-2 inhibitor.
Patent IL-149454-A0 (IL)
Title: Method for monitoring transmission quality
IPC: H04B7/26
Filed: 2000-11-13
Abstract: In wireless communications, it is necessary to monitor the transmission quality of communications channels to maintain system performance and operation. The invention provides a way of measuring bit error rates in channels at the receiver, without diminishing channel throughput by inserting quality monitoring data into the signal at the transmitter.
Patent IL-162438-A0 (IL)
Title: Provisioning aggregared services in a distributed computing environment
IPC: H04L29/08
Filed: 2002-12-11
Abstract: Methods, systems, and computer program products are disclosed for provisioning software resources used with aggregated web services. The disclosed techniques enable heterogeneous identity systems to be joined in the dynamic, run-time web services integration environment. Authentication and authorization may now be performed for the aggregated service, as well as for its sub-services. SOAP ("Simple Object Access Protocol") messages, as an example, may be used to relay identity information among distributed services, whereby credentials may be specified in the SOAP message header to accompany a service request specified in the SOAP message body.
Patent IL-169903-A0 (IL)
Title: Preformed compositions in shaped form
IPC: C08L81/02
Filed: 2005-07-26
Abstract: Preformed compositions comprising sulfur-containing polymers in shaped form and the use of preformed compositions in shaped form to seal apertures. In certain embodiments, the preformed compositions comprise a sulfur-containing polymer and a blend of fillers wherein the blend comprises substantially equal amounts of mica and polyamide.
Patent IL-172362-A0 (IL)
Title: Method of marking a product, marked product resulting thereof, and method of identifying same
IPC: G01N27/333
Filed: 2005-12-05
Abstract: Methods for marking a material and for identifying the authenticity and the genuine nature of a solid or liquid bulk material, by incorporating a marking composition containing at least one trace ion into the said bulk material, whereby the total concentration of the incorporated trace ions in the marked bulk material is chosen to be lower than the corresponding concentration of the same ions in standard sea water. The authenticity and the genuine nature or the adulteration level of the marked bulk material can be tested in-the-field using electro-chemical sensors, and confirmed in the laboratory using a method such as atomic absorption spectroscopy, ion chromatography or mass spectrometry.
Patent IL-179553-A0 (IL)
Title: Colored razor blades
IPC: C23C30/00
Filed: 2006-11-23
Abstract: Colored razor blades are provided. Methods for manufacturing such blades are also provided, including methods involving depositing an oxide coating prior to heat treatment of the blade material and heat treating under conditions selected to enhance the color of the coating.
Patent RO-125166-A0 (RO)
Title: Obtaining essential oil from rose petals by extraction in microwave field
Inventor: PĂTRAŞCU MARIANA
IPC: A23L27/10
Filed: 2009-03-31
Abstract: The invention relates to a process for obtaining an essential oil from rose petals. According to the invention, the process consists in extracting, in microwave field, the biological material consisting of fresh rose petals in a polar organic solvent chosen from among methanol, ethanol, acetic acid or non-polar organic solvent chosen from among hexane, dichloromethane, benzene and acetone, at a temperature of 50...70°C for 30...40 sec, at a microwave maximum power of 500 W and a frequency of 2450 MHz, afterwards the reaction product is cooled, in a controlled way, down to the temperature of 15...20°C, the heating and cooling being repeated 3 times for finalizing the reaction, afterwards the oil is separated by distillation and purified, there resulting an oil content of maximum 0.03...0.04%.
Patent RO-126354-A0 (RO)
Title: Conservative motor with central balance
Inventor: MANCIU MIOREL ALIN
IPC: H02K21/24
Filed: 2010-11-19
Abstract: The invention relates to a motor driven by a conservative force meant to equip an electric generator, a transportation means and various installations and equipments which use the mechanical force during operation. According to the invention, the motor comprises two U-shaped arms (1 and 2) mounted by means of a bearing (3) on a shaft (4) of a stator (18), between the last one and the arms (1 and 2) and a rotary module (15), respectively, there being mounted some bearings (17, 19 and 20), on the rotary module (15) there being fixed at the outer side a gin (21) and a braking system (22), on the shaft (4) there being mounted another bearing (7) in connection with which there is mounted a connection bridge (8) whereto there are linked some tensioned springs (5 and 6) also fixed to the arms (1 and 2), two pistons (9 and 10) being linked in some mobile rotation points, said pistons (9 and 10) being located in some chambers (11 and 12) cut in the arms (1 and 2), other two pistons (13 and 14) being also located in the chambers (11 and 12), some fluid volumes being located between the lasts ones and the other pistons (9 and 10).
Patent RO-135939-A0 (RO)
Title: Gravitational propulsion system
Inventor: BOGDAN ADRIAN
IPC: F03G3/00
Filed: 2022-04-21
Abstract: The invention relates to a propulsion system meant for land vehicles. According to the invention, the system consists of a hub (1) connected by means of a bearing (1a) to the chassis of a vehicle, some bi-telescopic arms (2) consisting of a long telescope (2a) joined to a short telescope (2b) which has a sole (2c) at the end, two assemblies (3 and 4) for blocking-releasing the long and short telescopes (2a and 2b) and a starter spring (5).
Patent IE-910668-A1 (IE)
Title: Prostaglandins for inhibiting cartilage damage
IPC: C07C405/00
Filed: 1991-02-27
Abstract: Misoprostol is used in the preparation of a medicament to inhibit cartilage damage, to reverse inhibition of cartilage synthesis, to inhibit the damaging effect of IL1 on cartilage integrity by direct damage or to inhibit cartilage synthesis.
Patent LU-87840-A1 (LU)
Inventor: REIMANN UDO
IPC: H04L12/56
Filed: 1990-11-14
Abstract: In a passive optical telecommunication system, in which signals are transmitted down from an exchange towards distant units in a burst stream and in which signals are transmitted up from the distant units towards the exchange using a TDMA method, wherein a distant unit transmits each burst in synchronised fashion with the aid of a delay device set individually from the exchange for each DU, the distant unit transmits the burst after only a rough delay time of one or more entire system clock periods before the transmission time required for a desired reception phase angle of the burst in the exchange, and only in the exchange is a precise delay centrally performed, in each case individually adjusted for each DU, on the bursts arriving in the exchange, to achieve the desired reception phase angle.
Patent MA-37290-A1 (MA)
Title: Inhibiteurs sélectifs de cdk8/cdk19 et leur utilisation dans des méthodes anti-métastatiques et chimiopréventives du cancer
Inventor: ROBINSON IGOR B
IPC: C07D239/94
Filed: 2013-02-01
Abstract: Cette invention concerne des composés et des méthodes destinés à inhiber la voie des inhibiteurs de kinases cyclines-dépendantes (cdki). Plus particulièrement, cette invention concerne des composés et des méthodes destinés à inhiber la voie des cdki pour étudier et intervenir dans les maladies liées à la sénescence et autres maladies liées aux cdki. Cette invention concerne de nouveaux composés ayant une solubilité et/ou une puissance améliorées, et des procédés pour les utiliser. Selon divers aspects, cette invention concerne le traitement du cancer; ainsi que des méthodes de chimioprévention et de prévention de la récurrence ou de la métastase des tumeurs. Des techniques diagnostiques pour le traitement de certains types de cancers faisant appel à des inhibiteurs spécifiques de cdk8/19 et/ou à la mesure des niveaux de cdk8 chez un patient sont également décrites.
Patent UY-25088-A1 (UY)
Title: Corte de hojas para armar cajetillas (atados) de cigarrillos
Inventor: REINHARD A SCHOCH
IPC: B65D85/10
Filed: 1998-07-09
Abstract: El objetivo del invento es la creación de un corte de hojas para una cajetilla de cigarrillos, novedosa, cuya forma sea diferente de la de prisma recto, y que tenga aristas laterales redondeadas. Corte de hojas para armar cajetillas (atados) de cigarrillos, que comprende una parte interna y envoltura, que tienen un lado anterior, un lado posterior, un fondo, una tapa y secciones laterales que unen el lado anterior y el lado posterior, y que tienen un borde de apertura. La cajetilla se distingue porque las secciones laterales están provistas de líneas de plegado, estriadas previamente, que permiten un plegado semirredondo de la parte interna y de la envoltura. El invento también refiere a un procedimiento para obtener las cajetillas de cigarrillos a partir de este corte, caracterizado porque: se pliega un corte de la parte interna alrededor de un cuerpo formador interno y se pegan sus aletas para pegar, para obtener una parte interna; la parte interna se quita del cuerpo formador interno, y se pliega un corte de la envoltura alrededor de la parte interna y se pega de ésta.
Patent CS-518286-A1 (CS)
Title: Device for ignition and combustion checking
Inventor: TOMILIN ALEXEJ I
IPC: F23Q5/00
Filed: 1986-07-09
Abstract: The combustion control appts. uses an ignition transformer (6) with its primary (5) coupled to a capacitor (4) via a relay switch contact (7). The primary and secondary are coupled to a common line at one side, with a combustion block (12) fed to one input of a clock generator (16) for an ignition heating pulse generator (15). (First major country equivalent to CS8605142) (-pp Dwg.No.1)
Patent ES-185883-A1 (ES)
Title: Un receptor de senales de ondas moduladas en velocidad angular
Filed: 1948-11-11
Abstract: Receptor para señales de onda portadora moduladas en frecuencia o en fase que tiene un amplificador modulado en impulsos para producir una señal de salida modulada en impulsos cuyas componentes de modulación de impulsos están modeladas en frecuencia o en fase con arreglo a la modulación de 1a portadora recibida y tienen una separación de frecuencia igual a 1a frecuencia de impulsos del amplificador; estando dicho receptor destinado a seleccionar y desmodular por lo menos una de dichas componentes de modulación de impulsos; caracterizado porque 1a frecuencia de impulsos es más baja que la fluctuación de frecuencia máxima de la portadora recibida y porque una porción del voltaje de salida del desmodelador se usa como voltaje de control para controlar 1as variaciones de frecuencia de 1as componentes de modulación de impulsos seleccionada y desmodulada con arreglo a la caracteristica de frecuencia del desmodulador.
Patent ES-262868-A1 (ES)
Title: 6alpha-halogen-9alpha-halogen-delta-pregnadiene-3-one compounds
IPC: C07J5/00
Filed: 1960-11-16
Abstract: The invention comprises steroids of the general formulae: <FORM:0958515/C2/1> <FORM:0958515/C2/2> wherein R represents an acyl group, R1 represents a hydrogen atom or an acyl group, R11 represents an acyl, alkyl or aryl group, R111 represents a keto or hydroxy group, and X represents a chlorine or bromine atom a process for the preparation of 9a -fluoro-D 1,3,5(6)-3-acyloxy-steroid by acylating 9a -fluoro-D 1,4-3-keto-steroids with an acylating agent at a temperature above 40 DEG C. in the presence of an acid catalyst and a process for the preparation of 9a -fluoro-6a - halo - D 1,4 - 3 - keto - steroids by reacting D 1,3,5(6)-3-acyloxy-steroids (which may be prepared by the method of the previous process) with a halogenating agent, for example an N-halogenated dicarboxylic acid imide or an N-halogenated carboxylic amide.
Patent ES-285197-A1 (ES)
Title: Improvements in or relating to underground gas storage tanks
IPC: B65G5/00
Filed: 1963-02-16
Abstract: Liquefied gas is stored in an underground chamber 10 which is excavated from a vertical pit 14, the access hole between the pit and the chamber being closed by a dam 16 of reinforced concrete preferably provided with a sealed manhole. Coaxial tubes 31, 32, 33 connect the chamber 10 with the ground surface 15, the tube 33 being for the supply or withdrawal of liquefied gas to or from the chamber, the space between the tubes 32 and 33 being used for the supply or withdrawal of gas to or from the spaces above the liquid surface in the chamber or for recycling the liquefied gas, and the space between the tubes 31 and 32 being used to insulate the pipes 32 and 33 from the ground. Insulation 34, Fig. 2 (not shown), e.g. polyurethane foam, may be fitted on the outside of the tube 32. The tube 31 is sealed to the ground by cement disposed around the tube, and the walls of the pit 14 are sealed by a covering layer of concrete. If the chamber 10 is in other than rock the chamber is lined with concrete, and it may also be lined with insulation, e.g. plastic foam. Prior to charging the chamber 10 it is thoroughly dried by the circulation of air of low relative humidity followed by dry nitrogen, and the pit 14 is purged by carbon dioxide gas which is placed in the pit bottom in the form of dry ice. When the chamber 10 is charged with the liquefied gas the pit 14 is simultaneously filled with water which forms an ice plug further sealing the access hole between the pit and the chamber. An auxiliary source of heat such as steam, hot water or electricity to melt the ice, and pumps for removing the resulting water, are provided in the pit 14 for use when it is necessary to gain access to the tank. More than one pit and/or chamber may be provided. Vertical metal plates may be provided to facilitate heat exchange and prevent stratification of liquid layers in the chamber or chambers. The latter may have temperature and stress gauges disposed at various points on the walls thereof and other temperature gauges may be disposed in the ground at a predetermined distance from the walls.
Patent ES-293109-A1 (ES)
Title: Stabilized bis- and tris-(beta-sulfatoalkyl) sulfonium inner salts
IPC: C07D215/36
Filed: 1963-11-02
Abstract: The invention comprises aqueous solutions of the salts of bis- or tris-(b -sulphato-alkyl)-sulphonium inner salts of the formula:- <FORM:1032882/C2/1> wherein R1, R2, R3 and R4 are H or C1-C3 alkyl R5 is the group (CHR3-CHR4-OSO3H) or a straight or branched substituted or unsubstituted alkyl, or a substituted or unsubstituted alkenyl, aryl, aralkyl, alicyclic or heterocyclic group containing a buffer system adapted to maintain the pH of the solution within the range 2.0 to 3.5, preferably in the range 2.7 to 3.3. The said solutions are stated to result in an improvement in the chemical stability of the salts of the sulphonium inner salts and may be obtained by adding to aqueous solutions of the salts a weak acid or an ammonium, alkali or alkaline earth metal salt of a weak acid and adjusting the pH to a desired value. Weak acids which are used are monobasic acids with a pK value not less than 2.0 nor greater than 5.0, for instance formic acid (pK 3.7) and acetic acid (pK 4.7) and polybasic acids with a pK value for the first hydrogen not less than 2.0 nor greater than 5.0, for example phosphoric acid (pK 2.15), citric acid (pK 3.1), tartaric acid (pK 3.0), succinic acid (pK 4.0) and maleic acid (pK 2.9). The amount of the weak acid or salt of a weak acid added to the aqueous solution is a small percentage of the weight of the solution preferably from 0.25% to 5%.
Patent ES-311776-A1 (ES)
Title: Analog information storing device
IPC: H04J3/18
Filed: 1965-04-13
Abstract: A multiplex analogue to digital converter comprises feedback loops for correcting losses in the circuitry. In the embodiment described 25 analogue signals are time-division multiplexed, channel 25 comprising a reference voltage equal to half the maximum analogue voltage range. The multiplexed signal passes via a storage capacitor and summing circuit to the converter which provides a serial-bit output. Due to variations in circuit parameters the voltage appearing at the converter input during channel 25 may not equal the reference voltage. To correct for this the most significant digit of the converter output during channel 25 is stored and controls a circuit which generates a positive or negative bias, as appropriate, over the next frame period, the bias being added to the analogue signals by the summing circuit. The second feedback loop counteracts the discharge of the storage capacitor during each channel time slot by comparing the state of charge of the capacitor at the beginning and end of channel 25 time slot. The store fed by the converter output controls a bias-generating circuit which responds to the -relative magnitudes of the most and least significant digit during channel 25 and passes an appropriate bias to the storage capacitor for the duration of one or more frames.
Patent ES-337740-A1 (ES)
Title: Valve
IPC: F16K5/06
Filed: 1967-03-08
Abstract: A spherical plug valve comprises a body 10 having inlet and outlet passages 15 and 23, a plug 34 disposed within the chamber and having a flow passage 36 for alignment with the inlet and outlet passages, a stem 30 with a handle 58 for rotating the plug, at least one seat recess 72 formed in the body, a seat ring 78 disposed in the recess, a retainer ring 80 interfitting with the ring 78 and defining therewith an annular groove, Fig. 2, of generally triangular crosssection having a restricted opening between the edges 85 and 87, a complementary shaped sealing ring 90 disposed within the groove having an inner diameter smaller than the outer diameter of the ring 80 (shown chain-dotted) to develop a high compression seal between the ring 90 and a base wall 95 of the groove adjacent the retainer ring. In a further embodiment, Fig. 4, not shown, the ring (100) has a frustoconical surface (102) with a smaller cone angle than that of the wall (84) of the groove. In Figs. 6 and 7, not shown, an annular protrusion (114) is formed on the ring.