baber/WOPTO huggingface dataset:
Patent AU-765512-B2 (AU)
Title: Antagonists specific for the corticotropin-releasing factor receptor type 2 (CRFR2)
Inventor: SPIESS JOACHIM
IPC: A61K38/00
Filed: 1999-07-23
Granted: 2003-09-18
Abstract: The present invention relates to an antagonist of the ligand of the Corticotropin-Releasing Factor Receptor, type 2 (CRFR2) lacking the 8 to 10 N-terminal amino acids of native sauvagine. The present invention also relates to an antagonist of the ligand of the Corticotropin-Releasing Factor Receptor, type 2 (CRFR2) lacking the 11 N-terminal amino acids of native sauvagine, wherein the N-terminal amino acid of said antagonist is a charged amino acid. Furthermore, the present invention relates to a polynucleotide encoding the antagonist of the present invention, a vector comprising the polynucleotide of the present invention, and a host comprising the polynucleotide or the vector of the present invention. Also described are a method for producing the antagonist of the present invention, antibodies directed the antagonist of the present invention, as well as anti-idiotypic antibodies directed against the antibody of the present invention. The present invention also relates to pharmaceutical and diagnostic compositions comprising the antagonist, the polynucleotide, the vector, the antibody, and/or the anti-idiotypic antibody of the present invention. Furthermore, the present invention relates to a kit comprising one or more of the above mentioned compounds of the present invention and to the use of one or more of these compounds for the preparation of a pharmaceutical composition for preventing and/or treating a Corticotropin-Releasing Factor Receptor, type 2 (CRFR2)-associated disease.
Patent AU-673564-B2 (AU)
Title: Glass substrates covered with a stack of thin coatings, application to glazings having properties of reflecting, in the infrared and/or properties in the field of solar radiation
Inventor: KOCH MELLE STEPHANIE
IPC: B32B17/06
Filed: 1994-02-01
Granted: 1996-11-14
Abstract: A transparent substrate (1), especially of glass, provided with a stack of thin layers comprising at least one metallic layer (5) with properties in the infrared, especially of low emission, arranged between two coatings based on dielectric material. The coating underlying the layer (5) with properties in the infrared comprises at least one wetting coating which is adjacent to the said layer (5) and which includes a layer (3) either based on tantalum oxide or based on niobium oxide. <IMAGE>
Patent AU-767878-B2 (AU)
Title: LY6H gene
Inventor: HORIE MASATO
IPC: A61K48/00
Filed: 1999-09-16
Granted: 2003-11-27
Abstract: The invention provides a brain-specific gene useful. in treating Alzheimer's disease, for instance, which comprises a nucleotide sequence cording for the amino acid sequence shown in SQ ID NO:1 and fragments thereof; an expression vector comprising the gene; a host cell comprising the expression vector; an expression product of the gene; an antibody against the product; a therapeutic and prophylactic composition for neurodegenerative disease; and the like.
Patent AU-603056-B2 (AU)
Title: Novel ketone photoinitiatiors for photopolymerization of ethylenically unsaturated compounds
Inventor: KOHLER MANFRED
IPC: C07C309/07
Filed: 1986-04-02
Granted: 1990-11-08
Abstract: PCT No. PCT/EP86/00183 Sec. 371 Date Dec. 3, 1986 Sec. 102(e) Date Dec. 3, 1986 PCT Filed Mar. 27, 1986 PCT Pub. No. WO86/05777 PCT Pub. Date Oct. 9, 1986.Compounds of the general formula I   <IMAGE> (I) wherein Z is CR1R2(OR3) or phenyl, R1 being H, C1-6-alkyl or phenyl, R2 being H, C1-6-alkyl or C1-6-alkoxy and R3 being H, C1-6-alkyl or C1-6-alkanoyl and Z' is Y-[(CH2)m-X]n-, X being CH2 or 0, Y being OH; COOH or SO3H including the alkali metal, alkaline earth metal or ammonium salts thereof and also the salts thereof with organic nitrogen bases; or NRR' in which R and R' are in each case H, C1-20-alkyl or C1-4-hydroxyalkyl, if appropriate quaternized or in the form of the acid addition salts, and n and m each being the numbers 1-4, are excellently suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds, in particular in aqueous systems.
Patent AU-633582-B2 (AU)
Title: Explosive detection screening system
IPC: G01N33/00
Filed: 1990-06-07
Granted: 1993-02-04
Abstract: An explosive detection screening system used for the detection of explosives and other controlled substances such as drugs or narcotics. The screening system detects the vapor and/or particulate emissions from the aforementioned substances and reports that they are present on an individual or object and the concentration of each substance detected. The screening system comprises a sampling chamber for the collection of the vapor and/or particulate emissions, a concentration and analyzing means for the purification of the collected vapor and/or particulate emissions and subsequent detailed chemical analysis of said emissions, and a control and data processing system for the control of the overall system.
Patent AU-767320-B2 (AU)
Title: Magnetic particle composition
Inventor: BAKER MATTHEW JOHN
IPC: H01F1/11
Filed: 2000-06-30
Granted: 2003-11-06
Abstract: A magnetic particle composition which can be used for separating biomolecules comprises magnetic materials of preferably less than five micron diameter bound to a negatively charged ion exchanger. The composition can be used to separate DNA from mixtures and to separate out cell debris.
Patent AU-649400-B2 (AU)
Title: Therapeutic application of an anti-invasion compound
Inventor: KOHN ELSIE C
IPC: A61P35/00
Filed: 1990-05-18
Granted: 1994-05-26
Abstract: Tumor invasion and metastasis is the most life threatening aspect of cancer. Invasion and metastasis is a multistep process. Cellular functions required for invasion are attachment, locomotion and directed migration. Regulation of these processes may be independent of cell growth. A carboxylamino-imidazole compound was found to be potent inhibitor of tumor cell attachment, motility, invasion, proliferation, and metastasis. This compound and equivalents thereof constitute a cancer treatment agent of particular use in the treatment of peritoneal carcinomatosis of ovarian cancer.
Patent AU-541868-B2 (AU)
Title: Xylene isomerisation
Inventor: TABAK SAMUEL ALLEN
IPC: C07C15/08
Filed: 1980-05-26
Granted: 1985-01-24
Abstract: Isomerization of xylenes in admixture with ethylbenzene by contact with a zeolite catalyst such as ZSM-5 is improved by use of zeolite which has been steamed at high temperature to reduce activity, the reaction being at a temperature above about 700 DEG  F. At these conditions, conversion of ethylbenzene follows a different reaction path which permits high conversion of ethylbenzene to benzene without loss of xylenes of disproportionation.
Patent AU-781700-B2 (AU)
Title: Bandage for relief of the musculature in muscle fibre tears
Inventor: KANDT OLIVER
IPC: G06F15/80
Filed: 2000-09-14
Granted: 2005-06-09
Abstract: The bandage (100) consists of a rectangular central section (1) to whose transverse edges (11,12) are fixed four pull-straps (21-24). The central section clings to the extremity in relation to the injured part of the muscular tissue. The two proximal pull-straps are guided in a diagonal movement in a distal direction, and the two distal pull-straps are guided in a proximal direction. The two proximal pull-straps cross over the injured spot proximally, and the two distal pull-straps cross over the injured spot distally One proximal and one distal pull-strap cross over to the side of the injury so that this is excluded. The ends of the pull-straps are fixed to the bandage.
Patent AU-771069-B2 (AU)
Title: Radio-contrast agents
Inventor: FRANK ARTUR
IPC: A61K49/04
Filed: 1999-09-15
Granted: 2004-03-11
Abstract: An imaging or contrast agent comprising a stereoisomer of a compound with at least one chiral centre, wherein said stereoisomer is in stereoisomeric excess and causes fewer adverse side effects on administration, or is less chemotoxic, than at least one other stereoisomer of said chiral compound.
Patent AU-625794-B2 (AU)
Title: Package with multi-ply side panels and strap handle
Inventor: GUNN CHARLES LLOYD
IPC: B65D5/475
Filed: 1990-08-10
Granted: 1992-07-16
Abstract: A package (18) having a handle (70) for housing granular or similar products. The handle is a substantially flat strap handle which has a barb member (76) on each end. The handle is inserted into two opposing openings (64) in the side wall (34) of the package. A section of the side wall adjacent each of the apertures includes a liner (80) which separates the granular contents of the package from the area immediately surrounding the aperture. The liner is adapted to prevent the flow of granular contents out through the aperture. The package can be formed from a sleeve which, even with the handle inserted, is substantially flat. Also, with the package assembled the handle rests against the side wall of the package allowing shipping virtually as if the package did not have a handle.
Patent AU-707703-B2 (AU)
Title: Vibrating cone crusher
Inventor: CORDONNIER ALAIN
IPC: B02C2/04
Filed: 1996-06-11
Granted: 1999-07-15
Abstract: PCT No. PCT/FR96/00879 Sec. 371 Date Apr. 6, 1998 Sec. 102(e) Date Apr. 6, 1998 PCT Filed Jun. 11, 1996 PCT Pub. No. WO96/41680 PCT Pub. Date Dec. 27, 1996A vibrating cone crusher which crushes material between a cone and a frustoconical ring located therearound. An annular frame supports the ring and a device for generating circular vibrations in a horizontal plane. Tie rods connect the frame to a cone holder. Vertical vibration that disrupts crusher operation is reduced or neutralized by positioning the center of gravity of the cone, the cone holder, the frame, and items supported thereon adjacent the plane of vibratory forces.
Patent AU-695778-B2 (AU)
Title: High temperature fuel cell, high temperature fuel cell stack and method for producing a high temperature fuel cell
Inventor: HOFER GERHARD
IPC: H01M8/124
Filed: 1996-07-15
Granted: 1998-08-20
Abstract: A high temperature fuel cell and a method for producing the same include at least one interconnecting conducting plate which is associated with at least one electrode. A contact layer is disposed between the interconnecting conducting plate and the electrode. The contact layer is produced from an oxide mixed crystal powder which has a spinel structure and also contains, in addition to chromium, a divalent element selected from the group Ti, V, Mn, Fe, Co and Cu. The contact layer has high thermodynamic stability in addition to sufficient electrical conductivity. A high temperature fuel cell stack includes a number of the high temperature fuel cells.
Patent AU-690037-B2 (AU)
Title: Coiled membrane filtration system
Inventor: BELFORT GEORGES
IPC: B01D63/10
Filed: 1996-08-02
Granted: 1998-04-09
Abstract: A method and apparatus for achieving reverse osmosis, microfiltration, nanofiltration and ultrafiltration, produces Dean vortices against a membrane surface which is advantageously in a form of a wound helical membrane tube.
Patent AU-542346-B2 (AU)
Title: Antitumor composition containing acridine derivatives
Inventor: KAPLAN MURRAY ARTHUR
IPC: A61K31/455
Filed: 1981-05-19
Granted: 1985-02-21
Abstract: Organic acid addition salts of the antitumor agent 4 min -(9-acridinylamino)methanesulfon-m-anisidide(m-AMSA) are made substantially more water-soluble by addition of nicotinamide. Solid dosage form compositions provided by the present invention permit intravenous administration of m-AMSA without the necessity of employing an undesirable non-aqueous vehicle such as dimethylacetamide.
Patent AU-748422-B2 (AU)
Title: Improved capo
Inventor: SHUBB RICHARD
IPC: G10D3/04
Filed: 1998-04-29
Granted: 2002-06-06
Abstract: An improved capo for use with various stringed instruments is provided. The capo comprises a frame having a top arm to contact the strings and a side arm, with a jaw member and a lever member both pivotally attached to the side arm. The jaw member contacts the back of the instrument neck when the capo is closed. Mounted on the lever member is a flexible member, having a follower surface that contacts the lower surface of the jaw member during the closing action of the capo and while the capo is closed. An adjustable stop passes through the lever member such that one end of the adjustable stop contacts the lower surface of the flexible member to urge the follower surface into contact with the lower surface of the jaw member. The improved capo of the invention is easier to attach and remove than capos of the prior art, maintains better alignment between the jaw member and the lever member, is less subject to frictional wear, and optimizes the degree of dropoff along the entire useable range of the capo.
Patent AU-601422-B2 (AU)
Title: Method of making steel
Inventor: KNAUSS WILLIAM FREDERICK JR
IPC: C21C5/28
Filed: 1987-04-30
Granted: 1990-09-13
Abstract: There is practiced a method of making low carbon silicon steel (32) in which the lining of the ladle (20) is made of dolomite instead of fireclay or alumina, and there is added to the ladle (20), before the metal is teemed into it, a pre-melted or prefused mixture containing appropriate portions of calcium silicate (12) lime magnesia (14), and spar (16), and argon (24) bubbling is practiced as before but preferably for a slightly longer period of time, and the ladle (20) is provided during argon (24) bubbling with a hood or lid (30). There is then obtained a product steel (32) with desirably low contents of oxygen (8) and nitrogen, and without penalty in the form of higher contents of aluminium and titanium in the finished steel (32).
Patent AU-644851-B2 (AU)
Title: Method and plant for improving keeping qualities of food products
Inventor: NOREN TOMMY
IPC: A23L13/60
Filed: 1991-01-31
Granted: 1993-12-23
Abstract: The method involves placing applicators having waveguides (15) and magnetrons (18) above and below an endless belt on which food products (12) are transported. Both the belt and the food packaging need to be transparent to microwaves. The applicators are arranged such that the standing waves in one are 90 degrees out of phase with the other. During heat treatment of the products, whose thickness should not exceed 10mm, are maintained at a temp. between 50-80 deg.C, for a period of 5 to 60 seconds.
Patent AU-719366-B2 (AU)
Title: Novel peptide
Inventor: NAKAHARA YO
IPC: C07K7/06
Filed: 1996-10-23
Granted: 2000-05-04
Abstract: A peptide comprising a peptide (A) of an amino acid sequence being abundant in basic amino acid residues and a peptide (B) of an amino acid sequence comprising at least two consecutive, hydrophobic amino acid residues wherein the peptide (B) is linked to the C-terminal of the peptide (A) directly or via several amino acid residues. The novel peptide of the present invention has the activity to inhibit growth of smooth muscle cells and a pharmaceutical composition comprising said peptide is useful for preventing or treating pathological conditions associated with growth of smooth muscle cells such as arteriosclerosis, restenosis after angioplasty, luminal stenosis after grafting blood vessel and smooth muscle sarcoma.
Patent AU-712352-B2 (AU)
Title: Multifocal lens, and method for production thereof
Inventor: WANDERS BERNARDUS FRANCISCUS M
IPC: G02C7/06
Filed: 1996-10-31
Granted: 1999-11-04
Abstract: PCT No. PCT/NL96/00428 Sec. 371 Date Apr. 29, 1998 Sec. 102(e) Date Apr. 29, 1998 PCT Filed Oct. 31, 1996 PCT Pub. No. WO97/16760 PCT Pub. Date May 9, 1997Multifocal lens provided with a reading part disposed near the bottom part and another lens, such as a distance lens, near the top part. According to the invention, the outer limit of the reading part lies on or within the (outer) radius RV of the remaining part of the lens. This means that no thickening is needed for the reading part, and a particularly gradual transition between reading and distance part can be provided.
Patent AU-762057-B2 (AU)
Title: Method and device for extracting iron by direct reduction
Inventor: OTTOW MANFRED
IPC: C21B13/00
Filed: 1998-04-21
Granted: 2003-06-19
Abstract: The invention relates to a method and a device for extracting iron by direct reduction, characterized in that the device has a separate reduction chamber in which the carbon is gasified and the iron oxide is reduced in close proximity, and a separate combustion chamber in which surplus reduction gases are burned and heat energy is yielded. According to the invention, the hot combustion gasses pass on their heat energy to the reduction gasses in a heat exchanger, so that this energy is transferred to the reduction gases effectively. The reduction gasses are force-circulated through the heat exchanger and through the carbon/bed of ore for this purpose.
Patent AU-652966-B2 (AU)
Title: Mid-sole or sole of shoes
Inventor: SHIBATA OSAMU
IPC: A43B17/03
Filed: 1991-10-29
Granted: 1994-09-15
Abstract: A mid-sole or sole of shoes for massaging the sole of a foot by stimulating it during walking, in which there are provided recess portions on the upper surface of a bottom plate by a wall portion, a plurality of blades in the recess portions and in the direction perpendicular to the longitudinal direction of the bottom plate, the blades being slanted in the same direction and having the same depth as that of the recess portion, a flexible cover sealed at the peripheral end portion of the upper surface of the bottom plate, and liquid injected and filled in the space provided between the bottom plate and the cover. <IMAGE>
Patent AU-726666-B2 (AU)
Title: Shoe cleats
Inventor: KELLY PAUL ANDREW
IPC: A43B5/00
Filed: 1998-08-19
Granted: 2000-11-16
Abstract: A shoe cleat is adapted to be removably secured in a holder provided on the shoe sole. In a combination of shoe cleat and holder, a screw-threaded spigot (12) on the cleat is inserted with rotation into a complementary socket (18) of the holder, and a locking means (26, 28) becomes interengaged to resist subsequent unscrewing of the assembly. The locking means comprises a ring of free-standing posts (34, 42) extending axially from the cleat and a ring of radially-projective teeth (26) on the holder, the rings being co-axial with the screw axis. During at least later stages of insertion of the spigot (12) into the socket (18), on relative rotation of the rings, engagement of the teeth (26) with the posts (34, 42) causes the posts (34, 42) to deflect resiliently and engagement of the teeth (26) between the posts (34, 42) causes interangagement of the locking means.
Patent AU-665939-B2 (AU)
Title: Liver enriched transcription factor
Inventor: SLADEK FRANCES M
IPC: A61P3/04
Filed: 1991-12-23
Granted: 1996-01-25
Abstract: HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). We have purified HNF-4 protein (54 kD) and isolated a cDNA clone encoding the protein. HNF-4 is a member of the steroid hormone receptor superfamily with an unusual amino acid in the conserved "knuckle" of the first zinc finger (DGCKG). This and the fact that HNF-4 does not bind significantly to estrogen, thyroid hormone or glucocorticoid response elements indicate that HNF-4 may represent a new subfamily. HNF-4 binds to its recognition site as a dimer and activates transcription in a sequence-specific fashion in nonhepatic (HeLa) cells. HNF-4 mRNA is present in kidney and intestine as well as liver but is absent in other tissues. DNA binding data suggest that HNF-4 could be identical to liver factor A1 (LF-A1), a factor previously shown to regulate the transcription of the  alpha -1 antitrypsin, apolipoprotein A1 and pyruvate kinase genes.
Patent BG-60475-B2 (BG)
Inventor: TRUMMLITZ GUENTER
IPC: C07D277/46
Filed: 1994-01-25
Abstract: Изобретението се отнася до 4-хидрокси-2н-1,2-бензотиазин-3-карбоксамид-1,1-диоксиди с обща формула     в която заместителите имат значенията, посочени в описанието, до метод за получаването им и долекарствени средства, които ги съдържат. Производните имат ценни фармакологични свойства, тъй като задържат възпалителните процеси, намаляват болките от тях и са особено подходящи при лечението на ревматични заболявания.
Patent CS-252479-B2 (CS)
Title: Self-locking nut
Inventor: TRAMEZZANI GIANCARLO
IPC: F16B39/12
Filed: 1984-12-29
Abstract: A self-locking nut (5) comprises a threaded upper collar (7) provided with longitudinal slots (10) dividing the collar into a plurality of circular arc segments (8) which are urged inwardly by a helical external spring (13); the slots (10) widen at least towards the free end of the collar (7) in V-shape (Fig. 1) V-, or rectangular or double rectangular shape (Figs. 3, 5, not shown), to prevent the segments from contacting one another, and hence avoid the accumulation of dirt in the slots (10). …<IMAGE>…
Patent DE-1947407-B2 (DE)
Title: Classifying and pairing device for mfd. parts - with processor control for one prodn. machine dependent on statistical analysis of dimensions of parts already obtained
IPC: G06F19/00
Filed: 1969-09-19
Abstract: The parts sorting device uses a computer to sort two sets of parts of different types into different classifications, according to one or more critical dimensions. The parts of the two sets are then combined in matching pairs, according to their classifications. The processor is coupled to a parts controller for mfr. of one set of parts, adjusting the mfg., machine to obtain parts with required critical dimensions, in accordance with stored information related to the dimensions of the parts already obtained. The statistical analysis is built up from the result of a pulse signal response fed through to a logue circuit.
Patent DE-2014125-B2 (DE)
Title: Stereo decoder changes automatically from mono to stereo - by responding to stereo signal presence and not to pilot by use of filters
IPC: H03D1/22
Filed: 1970-03-24
Abstract: Thestereo decoder changes over automatically from mono to stereo independently of the pilot tone and only when stereo signal are actually transmitted. The control signal for the changeover process switches is obtained using a filter (7) whose passband centre frequency lies within the frequency range occupied by the incoming multiplexed signals difference signal (Sm) and whose input receives at least this difference signal. The filter output is rectified and if necessary amplified and passed to the switching stage (6). The filter centre frequency lies near the subcarrier and includes both the difference signal sidebands.
Patent DE-2029590-B2 (DE)
Title: IC engine component temp. adjustment - is achieved by probe containing medium acting on bellows operating coolant control
IPC: F01P7/16
Filed: 1970-06-16
Abstract: A device is used for adjustment of the temp. of component parts of an internal combustion engine in which the constituent which alters the cooling is influenced by a temp. probe, the probe being exposed both to the temperature of the coolant and to that of the exhaust gases of the engine. Where a fluid cooled i/c engine is involved, the temp. probe (20) contains in one or several hollow chambers (19) an expanding or vaporising medium which acts on a working bellows (13) via a pipe connection (21). The bellows (13) thus operates the component (6) which influences the coolant temp.
Patent DE-2032902-B2 (DE)
Title: Engine fuel vaporising system - has jet opening uncovered by hydraulic servo and leading to fuel deflector plates
IPC: F02M29/02
Filed: 1970-07-02
Abstract: The hydraulic servo overcomes spring pressure to progressively open a series of fuel jets. The fuel jets (15) are arranged as bores in a cylindrical housing and are uncovered by the piston skirt (15). The piston is subject to fuel pressure which increases corresponding to load and engine revolution speed. Fuel deflector plates (16) are fitted to the combustion air guide tube (17) inner walls downstream of the fuel jet openings (15). Combustion air enters the air guide tube via the air slides (5) at up to three quarters of full throttle opening and on both tube sides at above three quarters load.