baber/WOPTO huggingface dataset:
Patent ES-2147542-T1 (ES)
Title: Aparato y metodo para agitar metal fundido usando campos electromagneticos.
Inventor: ISSIDOROV EDUARD A
IPC: F27D27/00
Filed: 1998-06-03
Abstract: Un método para agitar metal fundido durante su tratamiento dentro de un recipiente metalúrgico, que comprende: A. proporcionar un recipiente metalúrgico orientado verticalmente para alojar una masa principal de metal fundido dentro de una periferia definida por un revestimiento refractario; B. establecer un conducto de paso del metal fundido contiguo a dicha periferia del recipiente, estando dicho conducto de paso: (I) parcialmente definido entre una columna refractaria orientada sustancialmente de modo vertical en combinación con una estructura de pared refractaria que presenta una porción central orientada verticalmente y sustancialmente plana; y (II) comunicando con dicha masa principal del metal fundido de dicho recipiente, de modo que: el movimiento no turbulento sustancialmente orientado de modo horizontal del metal fundido, entre dicha columna refractaria y dicha estructura de pared refractaria: permite que (a) entre en dicho conducto de paso, (b) atraviese dicho conducto de paso, y (c) retorne el metal fundido desde dicho conducto de paso a dicha masa principal de metal fundido de dicho recipiente; C. colocar un núcleo alargado magnéticamente permeable que está dispuesto sustancialmente simétrico en relación a un eje longitudinal centralmente localizado de dicho núcleo, D. colocar una pluralidad de arrollamientos conductores eléctricamente individuales en una relación espaciada linealmente a lo largo de dicho núcleo alargado, E. establecer cíclicamente líneas de ujo magnético para in uir en dicho metal fundido haciendo que adquiera dicho movimiento no turbulento orientado horizontalmente en dicho conducto de paso, con dichas líneas de flujo magnético que están: (I) concentradas en el metal fundido en dicho conducto de paso, y (II) establecidas por excitación eléctricamente alterna tales como los arrollamientos linealmente espaciados; F. limitar verticalmente dicho movimiento horizontalmente orientado de metal fundido a través del conducto de paso por medios de tabiques selectivamente localizados: (I) contiguos a una porción de superficie superior de dicho cuerpo principal de metal fundido de dicho recipiente, y (II) contiguos a una porción de fondo de dicha masa principal de metal fundido de dicho recipiente.
Patent CY-1107940-T1 (CY)
Inventor: SHEFLER YURI
IPC: C12G3/06
Filed: 2008-05-09
Abstract: An improved process is provided to prepare vodka with exellent properties includes mixing water and absolute alcohol, treating the mixture with activated coal followed by filtration, adding sugar, aroma compounds and optionally other ingredients characterized in that the mixture of water and alcohol after the treatment with activated coal is cooled down to a temperature of about -10° C. to -15° C., at which temperature the mixture is maintained for about 4-8 hours, after which the resulting mixture is filtered, gradually adapted to room temperature, aroma and optionally other ingredients are added to the filtrate and optionally the resulting mixture at room temperature is filtered again before bottling. A new vodka is provided having a percentage of absolute alcohol in water of about 35-50 vol %, 4-6 mMol/l sugar, 0.05-0.2 mMol/l of sodium bicarbonate, and 0.02-0.04 vol % of extract of flax seeds of first discharge.
Patent CY-1108871-T1 (CY)
Title: Υποκατεστημενα παραγωγα αμινο-φουραν-2-υλ-οξεικου οξεος και αμινο-θειεν-2-οξεικου οξεος και η χρησιμοποιηση τους για τη θεραπεια ημικρανιας ή πονου
Inventor: SANDERMANN CORINNA
IPC: C07D307/42
Filed: 2009-03-12
Abstract: Η παρούσα εφεύρεση αφορά υποκατεστημένα παράγωγα αμινο-φουραν-2-υλ-οξεικού οξέος και αμινο-θειεν-2-οξεικού οξέος των γενικών τύπων (Ι-Α) και (Ι-Β), μεθόδους για την παρασκευή τους, φάρμακα που τα περιέχουν, τη χρησιμοποίηση των ενώσεων αυτών για την παρασκευή φαρμάκων για τη θεραπεία μεταξύ άλλων πόνου ή ημικρανίας και φαρμακευτικές συνθέσεις που τα περιέχουν.
Patent CY-1109774-T1 (CY)
Inventor: RIMMER TIMOTHY
IPC: B29C41/00
Filed: 2010-02-10
Abstract: A polymeric load carrying apparatus (10) and method of manufacture is disclosed. The apparatus comprises an outer shell composition and a filled inner core composition within the outer shell composition. The outer shell composition comprises less than 10% filler, and preferably substantially no filler, by weight, and the inner core composition comprises more than 15% filler, and preferably at least 40% filler, by weight. The filler is preferably a mineral sand.
Patent CY-1110610-T1 (CY)
Title: Διασπειρομενο δισκιο μποσερτανης
Inventor: HOLMAN LOVELACE
IPC: A61K31/513
Filed: 2010-03-09
Abstract: Η εφεύρεση σχετίζεται με διασπειρόμενα δισκία τα οποία περιέχουν την ένωση 4-τριτ-βουτυλο-Ν-[6-(2-υδροξυ-αιθοξυ)-5-(2-μεθοξυ-φαινοξυ)-2-(πυριμιδιν-2-υλο)-πυριμιδιν-4-υλο]-βενζολοσουλφοναμίδιο.
Patent CY-1112360-T1 (CY)
Inventor: HOLDWAY JOHN
IPC: G07F11/00
Filed: 2012-01-24
Abstract: A controlled delivery of product system for delivery of product in a vending machine obtained by a product acquisition system, said controlled delivery of product system comprising: 
an elevator cup for receipt of product from a product selection system of the vending machine, 
a delivery window covered by a delivery door for dispensing selected product, and a transport system for moving the elevator cup from the product selection system to the delivery door, 
said elevator cup being pivotally mounted for release of product through the delivery window upon opening of the delivery door, 
wherein the elevator cup engages the delivery door for opening the delivery door by vertical movement of the elevator cup.
Patent CY-1114140-T1 (CY)
Title: Ενωσεις 4-πυριδινονης και η χρηση αυτων για τον καρκινο
Inventor: BORZILLERI ROBERT M
IPC: A61P35/00
Filed: 2013-02-08
Abstract: Αποκαλύπτονται ενώσεις του Χημικού Τύπου (I) και άλατα εξ' αυτών. Επίσης, αποκαλύπτονται μέθοδοι χρήσης των ενώσεων στην αγωγή των υπερπλαστικών παθήσεων, όπως είναι ο καρκίνος, και των φαρμακευτικών συνθέσεων περιλαμβάνοντας μια τουλάχιστον ένωση του Χημικού Τύπου (I) ή ένα φαρμακευτικώς αποδεκτό άλας.
Patent CY-1114187-T1 (CY)
Title: Γλυκοπυρανοζυλο-υποκατεστημενα παραγωγα βενζονιτριλιου, φαρμακευτικες συνθεσεις που περιεχουν τετοιες ενωσεις, η χρηση τους και μεθοδοι παρασκευης τους
Inventor: ECKHARDT MATTHIAS
IPC: C07D309/10
Filed: 2013-07-17
Abstract: Γλυκοπυρανοζυλο-υποκατεστημένα, παράγωγα βενζονιτριλίου που ορίζονται σύμφωνα με τον γενικό τύπο Ι, συμπεριλαμβανομένων των ταυτομερών, των στερεοϊσομερών, των μιγμάτων αυτών και των αλάτων αυτών. Οι ενώσεις σύμφωνα με την εφεύρεση είναι κατάλληλες για τη θεραπεία μεταβολικών διαταραχών. Τύπος (Ι), όπου το R3 υποδηλώνει υδρογόνο, φθόριο, χλώριο, βρώμιο, ιώδιο, μεθυλο, αιθυλο, προπυλο, ισοπροπυλο, βουτυλο, sec-βουτυλο, ισοβουτυλο, tert-βουτυλο, 3-μεθυλο-βουτ-1-υλ, κυκλοπροπυλο, κυκλοβουτυλο, κυκλοπεντυλο, κυκλοεξυλο, 1-υδροξυ-κυκλοπροπυλο, 1-υδροξυ-κυκλοβουτυλο, 1-υδροξυ-κυκλοπεντυλο, 1-υδροξυ-κυκλοεξυλο, διφθορομεθυλο, τριφθορομεθυλο, πενταφθοροαιθυλο, 2-υδροξυ-αιθυλο, υδροξυμεθυλο, 3-υδροξυ-προπυλο, 2-υδροξυ-2-μεθυλο-προπ-1-υλ, 3-υδροξυ-3-μεθυλο-βουτ-1-υλ, 1-υδροξυ-1-μεθυλο-αιθυλο, 2,2,2-τριφθορο-1-υδροξυ-1-μεθυλο-αιθυλο, 2,2,2-τριφθορο-i-υδροξυ-i-τριφθορομεθυλο-αιθυλο, 2-μεθοξυ-αιθυλο, 2-αιθοξυ-αιθυλο, υδροξυ, διφθορομεθυλοξυ, τριφθορομεθυλοξυ, 2-μεθυλοξυ-αιθυλοξυ,μεθυλοσουλφανυλο, μεθυλοσουλφινυλο, μεθυλοσουλφονυλο, αιθυλοσουλφινυλο, αιθυλοσουλφονυλο, τριμεθυλοσιλυλο ή κυανό.
Patent CY-1115651-T1 (CY)
Title: Μεθοδος για την παρασκευη (1r, 2r)-3-(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης
Inventor: HELL WOLFGANG
IPC: C07C217/62
Filed: 2014-10-16
Abstract: Η παρούσα εφεύρεση αφορά σε μία μέθοδο για την παρασκευή (1R, 2R)-3-(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινόλης.
Patent CY-1120313-T1 (CY)
Title: Φαρμακευτικη συνθεση για δερματικη χρηση για να θεραπευεται ψωριαση που περιλαμβανει βιταμινη d και κορτικοστεοειδες
Inventor: DIDRIKSEN ERIK JOHANNES
IPC: A61P17/06
Filed: 2018-06-08
Abstract: Η παρούσα εφεύρεση αφορά σε μία φαρμακευτική σύνθεση για δερματική χρήση, η εν λόγω δε σύνθεση περιλαμβάνει ένα πρώτο φαρμακολογικώς δραστικό συστατικό Α που συνίσταται από τουλάχιστον μία βιταμίνη D ή ανάλογο βιταμίνης D και ένα δεύτερο φαρμακολογικώς δραστικό συστατικό Β που συνίσταται από τουλάχιστον ένα κορτικοστεροειδές.
Patent CY-1122701-T1 (CY)
Title: Απελευθερωση πρωτεϊνης με βαση βακτηρια
Inventor: ARRIEUMERLOU CÉCILE
IPC: C12N15/74
Filed: 2019-11-01
Abstract: Η παρούσα εφεύρεση αφορά σε ανασυνδυασμένα Gram-αρνητικά βακτηριακά στελέχη και τη χρήση αυτών για απελευθέρωση ετερόλογων πρωτεϊνών σε ευκαρυωτικά κύτταρα.
Patent GR-900300040-T1 (GR)
Title: Stabilization of hydrogenperoxide
Inventor: LANNIEL GENEVIEVE
IPC: C01B15/037
Filed: 1991-07-31
Abstract: Liquid composition for stabilising H2O2 in akaline medium which contains, per litre and in addition to water, 100 g to 300 g of potassium carbonate K2CO3 and 0 to 200 g of sodium carbonate Na2CO3 so as to make the sum of the quantities of K2CO3 and of Na2CO3 be 280 g to 300 g, 50 to 150 g of alkali metal hexametaphosphate and a quantity of an alkali metal salt of diethylenetriaminepentamethylenephosphonic acid such as to make the quantity of active diethylenetriaminepentamethylenephosphonic acid be between 15 g and 50 g.
Patent HR-P20100009-T1 (HR)
Title: Room arrangement, ship, building and method for constructing a room arrangement
Inventor: KORDELIN TAPIO
IPC: E04B1/348
Filed: 2010-01-07
Abstract: The invention relates to a room arrangement (20) comprising at least two superposed prefabricated load-bearing room units (1) which have been attached together. The room unit (1) has a ceiling (24), a floor (2), and at least two walls (3, 4, 5, 6), the ceiling (24), floor (2) and walls (3, 4, 5, 6) of a room unit (1) being connected together. Further, the said ceiling, floor and at least two walls are at least mainly of cellular board formed of two substantially parallel surface plates and of a core arranged between them, the core being firmly attached to the surface plates, wherein the surface plates and the core of the cellular board are made of metal. The invention relates also to method of constructing such room arrangement, and its uses.
Patent HR-P20100107-T1 (HR)
Inventor: SCHMEISSER DIRK
IPC: B01F23/00
Filed: 2010-03-01
Abstract: Rotacijski uređaj za tretman istopljenog metala, naznačen time, što se navedeni uređaj sastoji od šupljeg vratila (30) na čijem se jednom kraju nalazi rotor (40), pri čemu navedeni rotor (40) ima: krovni dio (42) i bazu (44), pri čemu su krovni dio (42) i baza (44) međusobno odvojeni i povezani sa više razdjelnika (50); prolaz (52) koji je definiran parom susjednih razdjelnika (50), krovnim dijelom (42) i bazom (44), s tim da svaki prolaz (52) ima ulaz (54) na unutrašnjoj površini rotora (40) i izlaz (56) na perifernoj površini rotora (40), a svaki izlaz (56) ima veću površinu poprečnog presjeka nego respektivni ulaz (54), a od njega je usmjeren ka periferiji, radijalno; tok strujanja koji je definiran kretanjem kroz vratilo (30) u ulaze (54) prolaza (52) i van kroz izlaze (56) ikomoru (48) u kojoj se može vršiti miješanje istopljenog metala i plina, pri čemu se komora (48) nalazi radijalno sa unutrašnje strane ulaza (54), i ima otvor u bazi (44) rotora (40) i nalazi se u toku strujanja između vratila (30) i ulaza (54), tako da pri radu kada uređaj rotira, dolazi do usisavanja istopljenog metala u komoru (48) kroz otvor u bazi (44) rotora (40) gdje se miješa sa plinom koji ulazi u komoru (48) iz vratila (30), a odakle se disperzija metal/plin ispumpava u prolaze (52) preko ulaza (54), prije no što se oslobodi iz rotora (40) preko izlaza (56); pri čemu, postoji veći broj prvih odsječaka (58a) u krovnom dijelu (42) i veći broj drugih odsječaka (58b) u bazi (44), svaki od prvih i drugih odsječaka (58a, 58b) odgovara jednom od prolaza (52). Patent sadrži još 20 patentnih zahtjeva.
Patent SI-1249511-T1 (SI)
Title: High speed steel with good high temperature strength manufactured by powder metallurgy
Inventor: MAILI INGRID
IPC: C22C38/60
Filed: 2001-12-05
Abstract: Steel object produced by decomposing a liquid metal stream of an alloy with nitrogen to form a metal powder and compacting the powder with optional deformation comprises a chemical composition containing (in weight %) 1.51-2.5 carbon, up to 0.8 silicon, up to 1.5 manganese, 3.5-4.5 chromium, 13.3-15.3 tungsten, 2.0-3.0 molybdenum, 4.5-6.9 vanadium, 10.05-12.0 cobalt, up to 0.52 sulfur, up to 0.2 nitrogen, maximum 100 ppm oxygen, and a balance of iron. The amount of manganese minus sulfur is at least 0.19. The ratio of concentrations of tungsten to molybdenum is 52.-6.5. Preferred Features: The steel has the following composition (in weight %) 1.75-2.38 C, 0.35-0.75 Si, 0.28-0.54 Mn, 3.56-4.25 Cr, 13.90-14.95 W, 2.10-2.89 Mo, 4.65-5.95 V, 10.55-11.64 Co and 0.018-0.195 N.
Patent SI-1683934-T1 (SI)
Title: Lock, in particular lock for room door
Inventor: SAUERLAND ECKHARD WILLI
IPC: E05B15/00
Filed: 2006-01-20
Abstract: The lock has a latch (2) provided in a housing, where a pusher nut (3) strikes the latch such that the latch shifts against a resetting force of a latch spring (10), from a front closed position to a rear closed position, through the rotation of the nut against a resetting force of a pusher nut spring. The springs (10,17) are formed as integral components of the latch and the pusher nut by plastic injection molding.
Patent SI-1919874-T1 (SI)
Title: Process for preparing benzazepine compounds or salts thereof
Inventor: TORISAWA YASUHIRO
IPC: C07D223/00
Filed: 2006-09-01
Abstract: This invention provides a process for preparing benzazepine compounds of the formula (1):   
wherein X 1  is a halogen atom, R 1  and R 2  are a lower alkyl group, or salts thereof as well as intermediate benzoic acid compounds in high yield and high purity on industrial scale, which are useful as an intermediate for preparing a pharmaceutically active 2,3,4,5-tetrahydro-1H-1-benzazepine compound having vasopressin antagonistic activity.
Patent SI-2212065-T1 (SI)
Title: Manual razor with pivoting shaving head
Inventor: BODET HERVE
IPC: B26B21/00
Filed: 2008-10-21
Abstract: The invention relates to a manual razor including a shaving head (10) having a attached on a handle (20), pivoting means (11, 21) between the head (10) and the handle (20) so that the head (10) can move from a use position perpendicular to the handle (20) into a stowage position parallel to the handle. In order for the razor to be easily stored while occupying as little space as possible, the blade can be pivoted without touching the blade, using a rack (21) provided on a sliding button located on the handle (20), and a toothed wheel (11) connected to the head (10), wherein the toothed wheel (11) and the rack (21) are sized and arranged to be in mutual engagement.
Patent DE-3486222-T2 (DE)
Inventor: HAKIM SALOMON DR MED
IPC: A61M27/00
Filed: 1984-07-23
Granted: 1994-05-05
Abstract: The described surgically-implantable device has a stepping motor that can be isolated physically from electrical power sources and powered by the influence of a magnetic field applied from outside the body. The stepping motor includes a rotor and one or more stator elements, the stator elements being composed of magnetically soft and permeable material shaped and positioned with respect to the rotor so that when magnetized under the influence of the external field the stator elements strengthen and orient the magnetic field in their vicinities so as to cause movement of the rotor. The stepping motor may be used in a surgically-implantable shunt valve in which the popping pressure is adjusted in finite increments by application of the external magnetic field.
Patent DE-3486339-T2 (DE)
Inventor: HORROBIN DAVID FREDERICK
IPC: A23L35/00
Filed: 1984-01-24
Granted: 1995-01-19
Abstract: A pharmaceutical or dietary composition for use in the treatment of atopic disorders, including eczema, asthma, allergies (especially allergic rhinitis), migraine and disorders associated with atopy including Crohn's disease, ulcerative colitis, otitis media, nephrotic syndrome, or benign breast disease, or breast or other cancer, or diabetes, or alcoholism, comprising effective amounts of one or more of the metabolites of linoleic acid (GLA, DGLA, AA, 22:4n-6 or 22:5n-6) and one or more of the metabolites of  alpha -linolenic acid (18:4n-3, 20:4n-3, 20:5n-3, 22:5n-3 or 22:6n-3) as such or in the form of an ester, salt, amide or other derivative convertible in the body thereto alone or in an acceptable pharmaceutical carrier or diluent.
Patent DE-3781895-T2 (DE)
Inventor: BURJES LOUIS
IPC: C07F9/165
Filed: 1987-08-07
Granted: 1993-02-11
Abstract: This invention is directed to borated amine salts of dihydrocarbyl monothiophosphoric acids, and to lubricating and functional fluid compositions containing said borated amine salts. The lubricating and functional fluid compositions have improved extreme pressure properties and high temperature stability. The borated amine salts of the invention may be characterized by the formula   <IMAGE> (I) <IMAGE> (II)  <IMAGE> (III)  or mixtures thereof wherein R1 and R2 are each independently hydrocarbyl groups containing from 1 to about 30 carbon atoms. In one preferred embodiment, the amine salts are derived from hydroxyhydrocarbyl amines. The lubricating and functional fluid compositions may contain, in addition to the borated amine salts, at least one nitrogen-containing composition prepared by the reaction of a hydrocarbon-substituted succinic acid-producing compound with at least about one-half equivalent, per equivalent of acid-producing compound, of an amine containing at least one hydrogen attached to a nitrogen atom. The lubricating compositions of the present invention are particularly useful as lubricating oils, functional fluids and greases.
Patent DE-3783683-T2 (DE)
Inventor: PECK V
IPC: D06P1/642
Filed: 1987-01-29
Granted: 1993-05-19
Abstract: This invention provides compositions comprising a physiologically-active agent and a compound having the structural formula   <IMAGE>   wherein each X, Y and Z may represent oxygen, sulfur or two hydrogen atoms, provided however that, when Z represents two hydrogen atoms, both X and Y represent oxygen or sulfur and when Z represents oxygen or sulfur at least one of X and Y must represent oxygen or sulfur; m is 2-6; R' is H or a lower alkyl group having 1-4 carbon atoms; n is 0-17 and R is -CH3,   <IMAGE> wherein R'' is H or halogen in an amount effective to enhance the penetration of the physiologically-active agent through the skin or other membrane of the body of an animal.
Patent DE-3789535-T2 (DE)
Inventor: NARITA HIROSHI
IPC: H01R13/629
Filed: 1987-11-03
Granted: 1994-10-13
Abstract: A header device (10) for receiving an IC card or pack (30), comprises a housing (11), which includes an IC-pack holder (12) having an opening (121) through which the IC pack (30) is inserted into and removed from the housing, and a pair of first levers (21) projecting into the IC-pack holder (12) so as to abut an end portion (31) of the IC pack (30), and a pair of second levers (22) located outside the holder. The first and second levers (22, 23) are coupled to each other at their respective proximal ends (211, 221), so that they are immovable relative to each other. The coupled levers (21, 22) are rotatably mounted on the housing (11). If the IC pack (30) is inserted into the housing (11) through the opening (12), the end portion (31) of the IC pack pushes the respective first levers (21), thereby rotating both the first and second levers (21, 22) in a first rotation direction. Then, if the second levers (22) are rotated in a second rotation direction reverse to the first rotation direction, the first levers (21) push the IC pack out of the housing.
Patent DE-3853145-T2 (DE)
Inventor: VAN COTT ELIZABETH
IPC: C12N15/00
Filed: 1988-12-16
Granted: 1995-08-31
Abstract: The present invention is directed to a method for cloning and producing the XbaI restriction endonuclease by 1) introducing the restriction endonuclease gene from Xanthomonas badrii into a host whereby the restriction gene is expressed; 2) fermenting the host which contains the vector encoding and expressing the XbaI restriction endonuclease, and 3) purifying the XbaI restriction endonuclease from the fermented host which contains the vector encoding and expressing the XbaI restriction endonuclease activity.
Patent DE-3876563-T2 (DE)
Inventor: BENTVELSEN GERARDUS JOSEPHUS
IPC: A01G27/00
Filed: 1988-09-21
Granted: 1993-04-08
Abstract: Apparatus for automatically watering plants, comprising a fluid tight reservoir (1) containing a substrate (2) onto which the plants (3,4,5) are positioned, means to apply fluid to said plants and means to receive the not directly absorbed fluid and conduct said fluid to a measuring reservoir. Analog level detectors (13) are used to generate level proportional signals to a processor (22) in which these signals are compared with reference signals to generate control signals to said means for applying fluid.
Patent DE-3877354-T2 (DE)
Inventor: JACQUET XAVIER
IPC: C12G1/032
Filed: 1988-06-24
Granted: 1993-08-05
Abstract: Device for submerging marc pomace (5) inside a series of vinification vats (6), characterised in that it comprises a submerging tool (1) attached to the end of a rod (3) with controlled means (4,10,12) for providing the movement of this rod in the three dimensions, these means being carried by a support (7) capable of being immobilised in relation to a vat (6) to perform the submerging operating theron, and then to be released and moved from this vat to another vat.
Patent DE-3879172-T2 (DE)
Inventor: EL HAGE SAMI G
IPC: A61B3/107
Filed: 1988-08-26
Granted: 1993-08-26
Abstract: There is disclosed apparatus which comprises a corneal topographer including a video camera or charge-coupled-device camera system for sensing images of rings of light reflected from the cornea, and means for processing the image rings to produce data useful in determining the contour of the cornea of a human eye.
Patent TR-199800870-T2 (TR)
Inventor: KLAUS MICHAEL
IPC: C07D213/80
Filed: 1996-11-05
Abstract: A compound of the formula wherein R1 is hydrogen or C1-6-alkyl; R2 is C1-6-alkyl or adamantyl; R3 is C1-6-alkyl or hydroxy; or R2 and R3 taken together are -(CR6R7)n-; R4 is C2-8-alkyl, C2-8-alkenyl, C2-8-alkynyl, -OCH2R5 or C2-8-alkanoyl; and hydrogen when R3 is hydroxy; R5 is C1-6-alkyl, C2-6-alkenyl or C2-6-alkynyl; R6 and R7 are hydrogen or C1-6-alkyl; Y is oxygen or sulphur; and n is 3, 4 or 5, and pharmaceutically usable salts of carboxylic acids of formula I act as selective ligands of retinoic acid  gamma -receptors and are useful for the treatment of epithelial lesions.
Patent TR-199902693-T2 (TR)
Inventor: DANG WENBIN
IPC: A61K47/30
Filed: 1998-04-30
Abstract: (I) formülünde gösterilen tekrarlanan monomerik birimlere sahip olan bir polimeri içeren biyo-bozunabilir, akabilir ya da esnek polimer bilesimleri anlatilmistir, bu formülde, R ve R'nin her biri, bagimsiz olarak, düz ya da dalli alifatiktir, bu alifatik, bir ya da daha çok araya girmeyen ikame edici ile ya ikame edilmekte ya da edilmemektedir; L, bir iki degerli sikloalifatik grubudur; R", H, alkil, alkoksi, aril, ariloksi, heteroksiklik ya da heterosikloksiyi kapsayan gruptan seçilmektedir; ve n, 5'den 1,000'e kadardir, burada, bahsedilen biyo-bozunabilir polimer, biyo-bozunmadan önce ve biyo-bozunma üzerine biyo-uyumlu olmaktadir. Bir düzenlemede, R, R ya da R"nin bir ya da daha çogu biyolojik olarak aktif maddedir. Polimere ilave olarak bir biyolojik olarak aktif maddeyi ihtiva eden amorf bilesimler ve bilesimler kullanilarak biyolojik olarak aktif maddelerin kontrol edilebilir biçimde salinmasi için yöntemler de anlatilmistir.