baber/WOPTO huggingface dataset:
Patent CA-2388377-C (CA)
Title: Medication for the treatment of chronic fatigue syndrome and related symptoms
Inventor: HORROBIN DAVID F
IPC: A61P25/00
Filed: 2000-10-12
Granted: 2011-02-01
Abstract: A method of treatment of disorders of neurological origin and drug formulations for use in the method are disclosed. These conditions comprise fatigue and associated syndromes of pain, weakness and depressed mood which are associated with chronic fatigue syndrome, brain injury and stroke, stress, fibromyalgia, and irritable bowel syndrome. The treatment comprises administering to a patient in need thereof a selective inhibitor of noradrenaline reuptake combined with either phenylalanine or tyrosine in the same dosage form or the same pack. The noradrenergic drug may be selected from lofepramine, desipramine or reboxetine. The selective inhibitor may be a combined inhibitor of both noradrenaline and serotonin reuptake such as venlafaxine, duloxetine or milnacipran, or an inhibitor of both noradrenaline and dopamine reuptake such as bupropion.
Patent CA-2394602-C (CA)
Inventor: WATERS NICHOLAS
IPC: A61P15/00
Filed: 2000-12-22
Granted: 2009-03-10
Abstract: New 3-substituted 4-(phenyl-N-alkyl)-piperazine and 4-(phenyl-N-alkyl)--piperidine compounds of Formula (1), wherein X N, CH, or C, however X may only be C  when the compound comprises a double bond at the dotted line; R1 is OSO2CF3, OSO2CH3, SOR3, SO2R3, COR3, NO2, or CONHR3 and when X is CH or C R1 may also be CF3, CN, F, Cl, Br, or I; R2 is a C1-C4 alkyl, an allyl, CH2SCH3, CH2CH2OCH3, CH2CH2CH2F, CH2CF3, 3,3,3-trifluoropropyl, 4,4,4- trifluorobutyl, or -(CH2) - R4; R3 is a C1-C3 alkyl, CF3, or N(R2)2; R4 is a C3-C6 cycloalkyl, 2-tetrahydrofurane or 3-tetra-hydrofurane, as well as pharmaceutically acceptable salts thereof are disclosed. Also pharmaceutical compositions comprising the above compounds and methods wherein the above compounds are used for treatment of disorders in the central nervous system are disclosed.
Patent CA-2396727-C (CA)
Title: Systems and methods for clot dissolution
Inventor: EVANS MICHAEL A
IPC: A61M25/01
Filed: 2001-01-24
Granted: 2011-12-13
Abstract: Clot disruption and dissolution are achieved using a catheter (12) having both an agitator (30) and the ability to deliver a thrombolytic agent. The catheter (12) is introduced to a target region with a blood vessel and the agitator (30) manipulated to engage and disrupt a region of clot therein. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator (30) is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.
Patent CA-2397132-C (CA)
Title: Optical disk and methods for recording and reproducing essencial information of optical disc
Inventor: LEE KYUNG-GEUN
IPC: G11B7/0045
Filed: 2002-08-08
Granted: 2008-11-18
Abstract: An optical disc and methods for recording essential information in and reproducing essential information from an optical disc are provided. The optical disc includes as a pattern of crystalline and amorphous marks storing essential information. The essential information recording method involves: heating an amorphous recording layer above the temperature of crystallization by radiating a beam according to a photoelectrically converted signal; and slowly cooling the heated recording layer to the temperature of crystallization or below to form a pattern of crystalline and amorphous marks. The essential information reproducing method involves: radiating a beam onto a pattern of crystalline and amorphous marks in which essential information of the optical disc is recorded; receiving the beam reflected from the pattern of crystalline and amorphous marks and photoelectrically converting the received beam to detect a signal; filtering the detected signal through a high-pass filter; and reproducing the essential information of the optical disc from the filtered signal. Essential information can be recorded in a recordable optical disc by phase change using an existing disc initializing apparatus after deposition of a recording layer and before initialization of the optical disc. Therefore, an additional recording apparatus and process is not necessary, and no damage caused by a high energy of laser occurs in the optical disc.
Patent CA-2398753-C (CA)
Inventor: CHACLAS ANGELO N
IPC: G07B17/00
Filed: 2000-12-21
Granted: 2005-05-03
Abstract: A postage printing system (10) includes a transport device (200) for feeding an envelope (20) in a path of travel through the postage printing system (10), a printer (1) for printing a postal indicia (30) and an ad slogan (50) on the enveloppe (20), and a control system (300) in operative communication with the transport device (200) and the printer (100). The control system (300) obtains an indication from the operator of a selected print location (40a, 40b, 40c, 40d, 40e, 40f, 42a, 42b, 42c, 42d, 42e, 42f) for the ad slogan (50) and determines if the postal indicia (30) and the ad slogan (50) may be printed in a single pass through the postage printing system (10).
Patent CA-2400618-C (CA)
Title: Wildlife guard for electrical insulator bushings
Inventor: BOWLING DAVID EDWIN
IPC: A01M29/24
Filed: 2001-02-14
Granted: 2010-04-20
Abstract: Wildlife guards for surrounding electrical insulator bushings and electrical conductors extending therefrom include pivotally connected first and second cover portions. Each cover portion includes a respective lever arm configured such that when a force is applied to the first and second lever arms by a portion of an electrical insulator bushing, the first and second cover portions pivot together into engagement in a closed position surrounding the electrical insulator bushing and a portion of the electrical conductor extending from the electrical insulator bushing.  A plurality of flexible fingers extending from adjacent edge portions of the cover portions allow an electrical conductor to extend therethrough while preventing the ingress of animals.
Patent CA-2403620-C (CA)
Inventor: MATTOUSSI HEDI
IPC: G01N33/53
Filed: 2001-03-20
Granted: 2012-01-10
Abstract: L'invention concerne des conjugués ioniques contenant une particule inorganique associée électrostatiquement à une macromolécule capable d'interagir de manière spécifique avec des espèces chimiques ou cibles biologiques prédéfinies.
Patent CA-2404954-C (CA)
Inventor: MOLLER RALF
IPC: B29C70/88
Filed: 2001-12-01
Granted: 2007-03-13
Abstract: The invention relates to an electrically-conducing floor covering, made from first particles of a polmeric material, covered with electrically-conducting second particles and compressed in the space between the upper and lower surface of the floor covering. The floor covering comprises at least one cut edge and the electrically-conducting second particles form conducting paths, which electrically connect the upper and lower sides of the floor covering. The first particles are made from at least one granulated elastomeric material and form a matrix in which the second particles form electrically conducting paths along the particle boundaries of the first particles.
Patent CA-2407593-C (CA)
Inventor: HAYAKAWA MASAHIKO
IPC: C07D405/04
Filed: 2001-04-26
Granted: 2011-01-11
Abstract: L'invention concerne des compositions médicinales s'utilisant comme inhibiteurs de phosphatidylinositol 3-kinase (PI3K) et comme agents anticancéreux. L'invention concerne également de nouveaux dérivés d'hétéroaryle condensés bicycliques ou tricycliques ou leurs sels produisant des effets bénéfiques sur l'inhibition de la PI3K et sur la prolifération de cellules cancéreuses.
Patent CA-2408481-C (CA)
Title: Autonomic reallocation of memory among buffer pools
Inventor: STORM ADAM J
IPC: G06F12/0866
Filed: 2002-10-17
Granted: 2009-10-06
Abstract: Buffer pools permit quick access to data. A simulated buffer pool extension (SBPX) is created for each buffer pool in a set of buffer pools. Data victimized from a buffer pool is represented in the associated SBPX. Requests for data that is not resident in a buffer pool but is represented in the associated SBPX are tallied. Periodically, an expected efficiency benefit of increasing the capacity of each buffer pool is determined from the tallies. Memory is reallocated from the buffer pool with the lowest expected efficiency benefit having remaining reallocatable memory to the buffer pool with the highest expected efficiency benefit having remaining reallocatable memory, until either one or both of the buffer pools exhausts its reallocatable memory. This is repeated until all reallocatable memory has been reallocated, until only one buffer pool with reallocatable memory remains, or until all buffer pools with remaining reallocatable memory have substantially the same expected efficiency benefit.
Patent CA-2408918-C (CA)
Title: Compound bow suited for youth, intermediates and training
Inventor: MCPHERSON MATHEW A
IPC: F41B5/10
Filed: 2001-06-01
Granted: 2006-08-01
Abstract: An archery bow (10) having a substantially constant draw weight having a handle portion (12), a flexible upper limb (14) supported by the handle portion, and a flexible lower limb (16) supported by the handle portion. The bow also having an upper rotational assembly (20) rotatably mounted upon the upper limb for rotation about a first axle (22). The upper rotational assembly having at least one upper cable track (24). A lower rotational assembly (30) rotatably mounted upon the lower limb for rotation about a second axle (32).  The lower rotational assembly having at least a first lower cable track (34) and a second lower cable track (36). The first lower cable track being a cable payout track, the second lower cable track constructed and arranged to payout a predetermined length of cable and simultaneously take up a second predetermined length of cable when the second cam assembly is rotated.
Patent CA-2409230-C (CA)
Title: Penetrating tip for trocar assembly
Inventor: MCFARLANE RICHARD H
IPC: A61B17/34
Filed: 2001-05-16
Granted: 2009-06-02
Abstract: A tissue penetrating instrument (10) of the type used in the medical field, wherein the instrument includes an elongated shaft (26) having a penetrating tip (22) mounted on one end thereof. The penetrating tip (22) includes a base longitudinally outward from the base and formed into an apex (32), which may be defined by a point, or other configuration specifically structured to facilitate penetration or puncturing of bodily tissue. The apex (32) may be substantially aligned with a linear extension of the central longitudinal axis or alternatively, may be spaced laterally outward or off-set from the central longitudinal axis of the shaft. The penetrating tip (22) further includes an exterior surface extending continuously between the apex and the base and configured to facilitate puncturing and enlargement of the tissue, in a manner which facilitates separation of the tissue and minimizes cutting, severing or otherwise damaging the contiguous bodily tissue surrounding the access opening.
Patent CA-2409783-C (CA)
Title: Procede et dispositif servant a limiter les maladies respiratoires parmi les occupants de batiments
Inventor: ROFF ROGER R
IPC: F24F11/00
Filed: 2001-05-31
Granted: 2005-07-26
Abstract: Procédé et dispositif servant à éviter la culture de micro-organismes, y compris des moisissures, du mildiou, des champignons, des virus, des bactéries et des insectes à l'intérieur des parois (10), des plafonds (15) et des planchers (45) d'un bâtiment (12) afin de les éliminer en tant que sources de maladies respiratoires et de maladies provoquées par les moisissures parmi les occupants du bâtiment (12). Ce procédé consiste à faire circuler de l'air plus sec et plus propre dans l'espace (24) situé entre la surface intérieure (18) et la surface extérieure (20) de la paroi (10) du plafond (15) et du plancher (45) du bâtiment (12). Ce dispositif comprend une pompe (28) et un réseau de conduits (26) montés dans les parois (10), plafonds (15) et planchers (45) et conçus pour créer un écoulement d'air sec absorbant l'humidité qui, sinon, favoriserait la culture des micro-organismes. De préférence, des capteurs (32) à l'intérieur de la paroi (10), du plafond (15) et du plancher (45) sont reliés à une unité de commande (30) servant à mettre la pompe (28) en service quand le niveau d'humidité s'élève à un niveau prédéterminé.
Patent CA-2415823-C (CA)
Inventor: HALLAM COLIN J
IPC: D04H1/00
Filed: 2001-07-09
Granted: 2011-01-11
Abstract: La présente invention concerne un mat (10) utilisé pour des matériaux composites d'armature, constitué d'au moins un premier (16) et un second (18) ensemble de fibres. Le premier ensemble de fibres (16) est posé sous forme de couche espacée et parallèle dans le sens du tissage et un second ensemble de fibres (18) est posé sous forme de couche espacée et parallèle perpendiculairement au sens de tissage. Ces fibres forment des interstices (22) dans lesquels un filament continu (20) est tissé pour fournir une stabilité à l'ensemble. Ce filament (20) comporte une partie noyau (34) et une partie gaine (36). La partie gaine, qui présente un point de fusion inférieur à celui de la partie noyau (34), est fondue à la chaleur pour former une pluralité de boucles fermées dans lesquelles sont piégés les ensembles de fibres respectifs. Ces fibres (16, 18) sont des fibres de verre ou des stratifils de fibres de verres et le filament (20) est un polyester. La partie noyau est constituée de poly(éthylène téréphthalate) à viscosité élevée et la partie gaine est constituée d'un poly(éthylène téréphthalate) à faible viscosité.
Patent CA-2418683-C (CA)
Inventor: AUDET GERALD P
IPC: H01L23/498
Filed: 2003-02-11
Granted: 2007-01-02
Abstract: An area-array integrated circuit package assembly are provided with a plurality of electrically conductive connectors attached to the package I.O. pads, that are used to connect the package to a printed circuit card or other component. The connectors comprise at least two parallel conductors flexing together in the same direction, electrically insulated from each other for a portion of their length between the package and printed circuit card to provide for reduced interconnection inductance. The connection with the component contact pads can be achieved by mechanically pressing the package and circuit card together or with the use of bonding material.
Patent CA-2419115-C (CA)
Title: Microparticles, and method and apparatus for forming same
Inventor: KIM KYEKYOON
IPC: A61K9/14
Filed: 2001-08-15
Granted: 2011-03-08
Abstract: A method of forming particles comprises accelerating a stream comprising a liquid; and vibrating the stream, to form particles. The particles may have a diameter that is smaller than the diameter of the nozzle used to form the stream, allowing for the formation of micro- and nano-sized particle.
Patent CA-2421595-C (CA)
Inventor: OVERHOLT TRENTON M
IPC: B65D6/38
Filed: 2001-09-10
Granted: 2010-02-09
Abstract: A wall structure (28, 30) for a container (10) includes at least one band member (54) which extends at least partially across the length of the wall structure (28, 30) proximate an upper surface of the wall structure (28, 30) and oriented substantially parallel thereto. The band member (54) has a wave-like cross-section (56) with a plurality of first peaks (60), adjacent and opposing second peaks (62), and inclined members (61) extending between the plurality of first and second peaks. The plurality of first peaks of the wave defines a first surface of the wall structure, and the opposing second peaks of the wave defines a second surface of the wall structure.
Patent CA-2422267-C (CA)
Title: Drying method for selectively removing volatile components from wet coatings
Inventor: SITZ RICHARD G
IPC: A61P1/08
Filed: 2001-09-21
Granted: 2010-02-16
Abstract: Method of selectively removing volatile components from a composition, comprising coating the composition onto a first substrate surface of a substrate (38), wherein the composition comprises a nonresident volatile component and a resident volatile component. The method further includes positioning at least a portion of the coated substrate (36) between a condensing surface (32) having a condensing surface temperature (Tc) and a heating surface (34) having a heating surface temperature (TH) that is greater than the condensing surface temperature, wherein the condensing surface (32) is in a spaced apart, confronting relationship to the coated surface (44) of the substrate (38) and wherein the heated surface (34) is in thermal contact with a second substrate surface (42) opposite the first substrate surface. In the method, the heated surface temperature (TH) and the condensing surface temperature (Tc) are such that the positioning step causes the nonresident volatile component to be selectively removed from the portion of the coated substrate. The method is suitable for forming transdermal drug delivery compositions (36).
Patent CA-2422699-C (CA)
Title: Compositions for treating diabetes
Inventor: YIN WEIDONG
IPC: A61K31/66
Filed: 2001-09-28
Granted: 2009-08-11
Abstract: Medicinal compositions for treating diabetes, in particular, medicinal compositions showing remarkable effects of treating and preventing type II  diabetes and diabetic complications which contain 4-diethoxyphosphinoylmethyl-N-(4-bromo-2-cyanophenyl)benzamide.
Patent CA-2426347-C (CA)
Inventor: MULVANEY ROBERT C III
IPC: B01J19/24
Filed: 2000-10-27
Granted: 2009-01-06
Abstract: A process and apparatus for producing reaction products by indirectly preheating and heating reactants by indirect heat exchange. The use of the preheating step simplifies the reaction zone design by eliminating the need of external exchangers and is particularly suited for an arrangement of plates that defines narrow channels for indirect heat exchange. The narrow channels are preferably defined by corrugated plates. The primary reaction channels (in section 42) will contain a catalyst for the promotion of the desired reaction product from the principal reactants. The heating fluid (30) passes through adjacent heating channels (in section 28) to provide indirect heating. At least a portion of the heating channels exchange heat with a non-catalytic portion of the reaction channels (in section 40) to preheat the reactants ahead of a catalytic section (in section 42) of the reaction channels.  Catalytic combustion within the heating channels (in section 28) may provide in-situ heat input for the heating medium (30). Suitable catalysts for the heating channels may comprise oxidation promoting catalysts.
Patent CA-2428152-C (CA)
Inventor: KESSLER BARBARA
IPC: A61M25/18
Filed: 2001-11-03
Granted: 2010-01-12
Abstract: An adapter is disclosed, which can be connected to the probe tube (2) of a ready installed PEG probe, cut off above the abdominal wall of the patient. Said adapter comprises a retaining member (5), supported by the abdominal wall, means (7) for fixing the proximal end of the PEG probe and means (8) for connecting a delivery tube. Said retaining member (5) is embodied as a separate piece, comprising an opening for the passage of the PEG probe, whilst the means (7, 8) for fixing the PEG probe and for connection of the delivery tub e form an insert piece (6), which may be inserted in the retaining member with a tight fit. Said adapter is characterised in being simple to manipulate and of a construction with a limited height.
Patent CA-2433409-C (CA)
Title: Use of mglur5 antagonists for the treatment of pruritic conditions
Inventor: GASPARINI FABRIZIO
IPC: A61K31/495
Filed: 2002-02-06
Granted: 2010-04-20
Abstract: The invention provides the use of mGluR5 receptor antagonists for the treatment of pruritic conditions.
Patent CA-2435861-C (CA)
Inventor: VIERICH RALF
IPC: G06F17/30
Filed: 2003-07-23
Granted: 2009-09-15
Abstract: The invention, when incorporated in a drill-through modeling tool (DMT) , allows all the elements affecting drill-through behavior to be aggregated in a single structure or set of structures, thereby allowing administration to be simplified, and also permitting easier integration with third-party tools. T he invention also provides for graphical displays of drill-through paths for a DMT user. These displays show the parameters and dependencies of each drill- through path and allow tool users to obtain a quick overview of the drill- through network and further, they allow the tool user to confirm drill-through dependencies at a glance. Drill-through objects may thus be manipulated and maintained in a graphical manner.
Patent CA-2435917-C (CA)
Title: Highly sensitive method for the detection of cytosine methylation patterns
Inventor: OLEK ALEXANDER
IPC: G01N27/447
Filed: 2002-03-08
Granted: 2011-05-17
Abstract: The invention relates to a method for detecting cytosine methylation in DNA samples. The inventive method comprises the following steps: a genomic DNA sample containing DNA to be examined and background DNA is chemically treated in such a way that all non-methylated cytosine bases are converted into uracil, the 5-methylcytosine bases remaining unchanged; the chemically treated DNA samples are amplified using at least two primer oligonucleotides and one polymerase, the DNA to be examined being preferred as a template as opposed to the background DNA; the amplificates are analysed; and the methylation status in the DNA to be examined is inferred from the presence of an amplificate and/or from the analysis of further positions.
Patent CA-2437863-C (CA)
Inventor: AHARONI ASAPH
IPC: C12N9/88
Filed: 2002-02-12
Granted: 2013-05-28
Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and biocontrol agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.
Patent CA-2440397-C (CA)
Inventor: SCHUTZBACH JAMES SCOTT
IPC: G01F1/00
Filed: 2002-03-08
Granted: 2008-11-18
Abstract: Procédé et système de surveillance et d'analyse de flots dans un système d'égouts. Le procédé consiste à utiliser un ensemble de surveillance pour collecter les données représentatives d'un volume de flux réel d'une substance liquide dans un premier endroit tel qu'un tuyau d'égout, stocker les données sur le volume des flux dans une mémoire, maintenir les données préalablement stockées dans la mémoire, déterminer un volume des flux prévus et comparer le volume des flux réels avec le volume des flux prévus pour obtenir une valeur de différence. Le volume des flux prévus dépend des données sélectionnées à partir des données préalablement stockées ainsi que du jour et de l'heure qui correspondent aux données sur le volume des flux réels comme aux données sur le volume des flux prévus. Le volume des flux prévus peut aussi dépendre des données supplémentaires correspondant à un événement de pluie. Si la valeur de différence dépasse une valeur de variance prédéterminée, le procédé peut aussi comprendre l'indication d'une perte de flux. Si la valeur de différence ne dépasse pas une valeur de variance prédéterminée, le procédé peut aussi consister à stocker le volume des flux réels dans la mémoire sous forme de données d'échantillonnage stockées. Le procédé peut aussi consister à transmettre les données sur la vitesse des flux, la profondeur et/ou les valeurs réelles à travers un réseau de données tel que l'Internet à destination d'un dispositif de calcul. Le volume des flux réels peut aussi se présenter comme une moyenne mobile du volume des flux.