baber/WOPTO huggingface dataset:
Patent CA-3117545-A1 (CA)
Title: Intraoral ferrule with arch for preventing snoring and apnea
Inventor: NAVARRO SEGURA MIGUEL
IPC: A61F5/56
Filed: 2019-10-22
Abstract: An intraoral ferrule (1) with an arch (2), the arch of which protrudes from the anterior inner part of the ferrule and with extensions (4) to the posterior part that run parallel to the bite plane to a point (6) at which they turn and are joined to a curved region (3), forming the end of the arch, which retains the tongue (7), thereby preventing the possible displacement thereof towards the posterior part of the user's buccal cavity.
Patent CA-3119349-A1 (CA)
Inventor: KURANDA KLAUDIA
IPC: A61K48/00
Filed: 2019-11-15
Abstract: Sont divulgués ici des méthodes d'analyse ou de détection de la présence d'inhibiteurs et/ou d'activateurs non-anticorps de transduction de cellules vecteurs de virus adéno-associé (AAV) dans un échantillon biologique provenant d'un sujet. Sont également divulguées des méthodes d'analyse ou de détection de la présence d'anticorps de liaison à AAV qui inhibent, réduisent ou diminuent la transduction de cellules vecteurs d'AAV dans un échantillon biologique provenant d'un sujet. Les méthodes reposent, en partie, sur l'utilisation de particules d'AAV à capside vides pour absorber des anticorps de liaison à AAV, pour détecter des activateurs ou des inhibiteurs de la transduction de cellules vecteurs d'AAV, lorsqu'ils sont présents, dans un échantillon biologique analysé pour rechercher des anticorps neutralisant AAV (NAbs).
Patent CA-3120176-A1 (CA)
Title: Optimization of in vitro isolation of nucleic acids using site-specific nucleases
Inventor: OUELLET JIMMY
IPC: C12N9/22
Filed: 2019-11-18
Abstract: The present invention relates to a method of preparing a nucleic acid molecule comprising a target region for isolation from a sample, said method comprising the steps of contacting a population of nucleic acid molecules with a first Class 2 Type V Cas protein-gRNA complex, wherein the gRNA comprises a guide segment that is complementary to a first sequence within a nucleic acid molecule, said first sequence being located adjacent to said target region, thereby forming a Class 2 Type V Cas protein-gRNA-nucleic acid complex, and a protector molecule,contacting the population of nucleic acid molecules with at least one enzyme having exonuclease activity, recovering said nucleic acid molecule comprising the target region from the Class 2 Type V Cas protein-gRNA-nucleic acid complex formed in step a), and contacting the nucleic acid molecule of step c) with a processive polymerase, preferably a mesophilic or thermophilic polymerase, even more preferably a T4 DNA polymerase.
Patent CA-3120603-A1 (CA)
Inventor: TREWERN DAVID
IPC: H02G15/013
Filed: 2018-11-28
Abstract: A hydrofoil system is disclosed, having a fuselage with a propeller mounted to one end of the fuselage and a wing extending laterally from the fuselage. The fuselage is configured for removable attachment to a mast, so that the mast when attached extends from the fuselage in a direction substantially orthogonal to the longitudinal axis and also substantially orthogonal to the wing. A tail wing is connected to the fuselage by a tail strut, so that the tail wing is positioned beyond the end of the fuselage to which the propeller is attached. A motor is housed in the fuselage and has a cable connected thereto, the cable extending outside the fuselage, wherein a removable sealing system inhibits water ingress to the motor at the location where the cable is connected when the sealing system is installed in the fuselage. The sealing system comprises an end cap that seals against an inside surface of the fuselage, a deformable gland seal that is fitted about the cable, and a seal cap that clamps the gland seal within the hole, thereby compressing the gland seal and causing the gland seal to press against the cable and the inside of the hole.
Patent CA-3123883-A1 (CA)
Title: System and method of digital product onboarding and distribution using the cloud service brokerage infrastructure
Inventor: BOTE MARC SERRAT
IPC: G06F15/173
Filed: 2019-12-28
Abstract: The present disclosure relates to a system and method of digital product onboarding and distribution using a cloud service brokerage (CSB) infrastructure, whereby the method includes creating a product model at a vendor portal computing device, the product model based at least in part on a first product, storing the product model at a marketplace product catalog, exporting the product model to a third-party CSB platform, exporting the product model to an ordering system, configuring an application programming interface (API) to receive a request for integration of the first product, receiving, at the order system, the request for the first product, wherein the request includes a request product model payload, and fulfilling, at the order system, the request for the first product, based at least in part on a product attribute.
Patent CA-3126090-A1 (CA)
Inventor: BENTLEY MARCUS ALLEN
IPC: C11D1/12
Filed: 2020-02-26
Abstract: The present invention herein provides a disinfectant composition containing a) an effective amount of a hydrogen peroxide source, b) a blend of at least one aromatic alcohol and at least one glycol or glycol ether, c) at least one nonionic and/or anionic surfactant and d) at least one acid. Furthermore a method of using the disinfectant composition is also provided, whereby the composition can be applied to any surface and effectively kill a majority of tuberculosis and/or M. terrae microbes; resulting in a >5 log reduction at a contact time of 5 minutes or less.
Patent CA-3128050-A1 (CA)
Title: Methods and compositions for developing target specific exosome and growth factor products
Inventor: PETTINE KENNETH ALLEN
IPC: C12N5/00
Filed: 2020-01-30
Abstract: Disclosed are methods for making individualized mesenchymal stem cell growth factor and exosome compositions and methods of their use to treat skin disorders, hair loss, pain, rheumatoid arthritis, osteoporosis, autism, depression, biopolar disorder, anxiety, celiac disease, and cancer.
Patent CA-3128941-A1 (CA)
Inventor: CARON DELPHINE
IPC: G06F16/23
Filed: 2020-01-31
Abstract: A method in an aggregator server of synchronizing data records responsive to variable update notifications includes: receiving, from a provider system, an update notification corresponding to a master data object at the provider system; retrieving a record containing a local data object corresponding to the master data object; determining whether the update notification contains update definitions identifying changes to the master data object; selecting between a delta synchronization mode, when the determination is affirmative, and an object comparison synchronization mode, when the determination is negative; for the delta synchronization mode, updating the local data object according to the update definitions; for the object comparison synchronization mode, obtaining a copy of the master data object, and updating the local data object based on a comparison between the local data object and the copy of the master data object; and storing the updated local data object in the record at the aggregator.
Patent CA-3129082-A1 (CA)
Inventor: BELT DARWIN WAYNE
IPC: H04W4/024
Filed: 2020-02-06
Abstract: A system for wireless acquisition and presentation of local spatial information includes a portable computing device in communication with a wireless receiver, the portable computing device designed and configured to receive a first signal from a first transmitter at a first location, parse the first signal for at least a textual element, extract, from the at least a textual element, an identifier of the first transmitter, establish a spatial bounding constraint as a function of the identifier, retrieve regional descriptive data from a spatial information data structure as a function of the identifier, wherein the regional descriptive data describes information within the spatial bounding constraint, generate a local area description as a function of the regional descriptive data and the spatial bounding constraint, and present the local area description to a user of the portable computing device.
Patent CA-3131630-A1 (CA)
Inventor: GATELY STEPHEN
IPC: C07C259/10
Filed: 2020-03-25
Abstract: The disclosure provides a method of treating a malignant rhabdoid tumor in a subject in need thereof including administering to the subject a therapeutically-effective amount of (S)-N-hydroxy-2-(2-(4-methoxyphenyl)butanamido)thiazole-5-carboxamide and pharmaceutically acceptable salts thereof. In certain embodiments of this method the malignant rhabdoid tumor is small cell cancer of the ovary of the hypercalcemic type (SCCOHT).
Patent CA-3131668-A1 (CA)
Inventor: KAMIKAWABATA MASAHITO
IPC: H02K1/18
Filed: 2019-12-17
Abstract: This laminated core is provided with: a plurality of magnetic steel sheets laminated to each other; and adhesion portions arranged between the magnetic steel sheets adjacent to each other in the lamination direction to bond these magnetic steel sheets. The adhesion portions partially bond the magnetic steel sheets adjacent to each other in the lamination direction to each other, and the adhesion portions adjacent to each other in the lamination direction have mutually different arrangement regions in plan view from the lamination direction.
Patent CA-3132623-A1 (CA)
Title: Quinones bicycliques et tetracycliques substituees et procedes d'utilisation associes
Inventor: NEAMATI NOURI
IPC: A61K31/164
Filed: 2020-03-06
Abstract: La présente invention s'inscrit dans le domaine de la chimie médicale. En particulier, l'invention concerne des composés à petites molécules ayant des échafaudages de quinone bicycliques et tétracycliques qui ont des activités antiprolifératives à travers, par exemple, l'induction d'espèces réactives de l'oxygène. L'invention concerne en outre des procédés de préparation et des procédés d'utilisation de ces composés pour traiter le cancer (par exemple, le cancer du pancréas, la leucémie, le cancer du poumon non à petites cellules, le cancer du côlon, le cancer du SNC, le mélanome, le cancer de l'ovaire, le cancer du sein, le cancer du rein et le cancer de la prostate).
Patent CA-3137547-A1 (CA)
Title: Enclosure for rearing animals, for example for dairy cattle, and system for reducing heat stress for a feeding area in such an enclosure
Inventor: BIORET JEAN-VINCENT
IPC: A01K1/00
Filed: 2020-05-06
Abstract: The present invention concerns an enclosure (1) for rearing animals, for example for dairy cattle, that comprises a feeding area (A) that is connected to a fodder table (T) via a barrier (C). In order to reduce heat stress, the feeding area (A) comprises a system for spraying water (5) onto the animals (B) present in the feeding area (A), comprising: - several nozzles (7) that are each arranged to diffuse a jet of water (J) in a location (E), and - control means (8), for controlling at least the flow rate of the jet of water (J) diffused by the nozzles (7). The water spraying system (5) is configured to diffuse the jet of water (J) within each location (E) so as to wet the back line (B1), and optionally the flanks (B2), of the animal (B) that is present.
Patent CA-3139173-A1 (CA)
Inventor: UEMIZO YOSHIAKI
IPC: B25J15/08
Filed: 2020-06-16
Abstract: L'invention vise notamment à fournir une main robotisée capable de retirer, avec une haute probabilité, une feuille de papier d'un récipient de stockage de billets de banque, dans lequel une surface exposée du côté recto de la feuille de papier est considérablement petite. Selon l'invention, la main robotisée 300 comprend un premier doigt 310, un second doigt 320, et un mécanisme de déplacement de doigts 330. Le premier doigt et le second doigt s'étendent dans une première direction Dy. Le second doigt est disposé de façon à faire face au premier doigt. Le mécanisme de déplacement de doigts déplace le premier doigt et/ou le second doigt dans une direction où le premier doigt et le second doigt se font face. Dans la première direction, la position de pointe Tm du premier doigt diffère de la position de pointe Ts du second doigt.Figure sélectionnée : Fig. 3
Patent CA-3144067-A1 (CA)
Inventor: MOLINE MARGARET
IPC: A61K45/06
Filed: 2020-06-25
Abstract: L'invention concerne des méthodes d'amélioration de l'efficacité subjective du sommeil, de réduction du délai d'endormissement subjectif, et/ou de réduction du réveil subjectif après l'endormissement chez des sujets comprenant l'administration au sujet de 5 mg ou 10 mg de lemborexant ou d'une dose équivalente d'un sel pharmaceutiquement acceptable de celui-ci. L'invention concerne également le lemborexant ou un sel pharmaceutiquement acceptable de celui-ci, destiné à être utilisé pour améliorer l'efficacité subjective du sommeil, réduire le délai d'endormissement subjectif, et/ou réduire le réveil subjectif après l'endormissement chez un sujet, comprenant l'administration au sujet de 5 mg ou 10 mg de lemborexant ou d'une dose équivalente d'un sel pharmaceutiquement acceptable de celui-ci.
Patent CA-3146542-A1 (CA)
Title: Method of preparing a solid dosage form and a lubricant
Inventor: GUHA ASHISH
IPC: A61K9/20
Filed: 2020-08-07
Abstract: The present invention is related to a method of preparing a solid dosage form, comprising the steps of: a. preparing a lubricant consisting of at least one polyunsaturated fatty acid salt; b. adding the lubricant and ingredients for the solid dosage form to a mixer; c. optionally carrying out one or more of the following steps: granulation, drying and sizing, d. blending the contents of the mixer; and e. compressing or slugging the blended contents to produce a solid dosage form. Solid dosage forms prepared according to this method and the use of PUFA salts as lubricant in tableting applications for compression of solid components are further comprised by the present invention.
Patent CA-3147870-A1 (CA)
Title: Infusion pump cassette having integrated pinch clip occluder
Inventor: AZAPAGIC AZUR
IPC: A61M5/142
Filed: 2020-07-10
Abstract: A cassette usable with an infusion pump includes a monolithic cassette body and a segment of resiliently deformable tubing for conveying a flow of liquid. The monolithic cassette body has an integrally formed free-flow protection device including a fixed pinch element and a deflectable pinch arm having a movable pinch element. The pinch arm normally resides in a closed position wherein the pinch elements cooperate to deform the tubing segment to stop flow. The pinch arm is resiliently deflectable away from the closed position to an open position permitting flow. Deflection of the pinch arm away from the closed position spring biases the pinch arm for automatic return to the closed position. The pinch arm may be moved to the open position by operating a door of the pump when the cassette is loaded in the pump, and manually for priming when the cassette is not loaded in the pump.
Patent CA-3149588-A1 (CA)
Inventor: PLANZ OLIVER
IPC: A61K31/4458
Filed: 2020-08-27
Abstract: The present invention relates to MEK inhibitors that are capable of displaying one or more beneficial therapeutic effects. The MEK inhibitors can be used in the prevention and/or treatment of viral infection. MEK inhibitors in combination with a cap-dependent endonuclease inhibitor are capable of displaying one or more beneficial therapeutic effects in the treatment of viral diseases.
Patent CA-3151012-A1 (CA)
Inventor: FRATTOLILLO FRANK
IPC: G01S17/86
Filed: 2022-03-03
Abstract: Aspects of the present disclosure involve systems, methods, and devices for determining the presents of a human body in a given area based on lidar intensity values and heat transferred to the environment. A system includes one or more processors of a machine, a machine-storage medium storing instructions that, when executed by one or more processors, cause the machine to perform operations comprising accessing an incoming data point output by a lidar unit and a heat/temperature unit in any given area. The operation may further include using inference models of both reflective measurement (lidar) and heat dissipation (IR radiation) measurement (temperature), a reflectance value of an object based on incoming data. The inference model comprises a mapping of previously collected data points to a coordinate system using associated range values and raw intensity values for both incoming data intensity values. The operation may further include the inferred values being determined by one or more characteristics based on incoming data.
Patent CA-3151656-A1 (CA)
Inventor: BONAMY R DAVID
IPC: E04C2/12
Filed: 2020-09-09
Abstract: A lumber use designation system includes a building construction plan that shows the layout, wall thickness, wall height, ceiling angles, etc., of a structure, which are color coded from a series of color codes each corresponding to a preselected, standard board size and length of lumber that should be selected for constructing a particular portion of the structure. The system includes a supply of lumber boards marked with a color code correlating to the color code found on the construction plans. The lumber boards may be imprinted by an ink spray head. A method of installing lumber during the construction of a structure is disclosed.
Patent CA-3153086-A1 (CA)
Title: Methods, systems, and devices for the diagnosis of behavioral disorders, developmental delays, and neurologic impairments
Inventor: ABBAS ABDELHALIM
IPC: A61B5/00
Filed: 2020-09-04
Abstract: Described herein are methods, devices, systems, software, and platforms used to evaluate individuals such as children for behavioral disorders, developmental delays, and neurologic impairments. Specifically, described herein are methods, devices, systems, software, and platforms that are used to analyze video and/or audio recordings of individuals having one or more behavioral disorders, developmental delays, and neurologic impairments.
Patent CA-3154085-A1 (CA)
Inventor: YAJKO MICHAEL P
IPC: B65D1/20
Filed: 2022-03-29
Abstract: Provided is a storage container for storing a material, the storage container including a lid and a container body having a first portion for holding the material and a second portion to which the lid is configured to be attached. The second portion is spaced from the first portion in a longitudinal direction by a collar defining a gap between the first and second portions.  The first portion has a wall with a closed bottom portion defining a cavity for the material and the second portion has a wall defining an opening for accessing the cavity.
Patent CA-3155053-A1 (CA)
Inventor: LENG LUHAO
IPC: A47C31/12
Filed: 2020-10-16
Abstract: L'invention concerne un module élastique d'un coussin élastique destiné à être utilisé dans des meubles, et un coussin élastique ayant le module élastique. Le module élastique comprend un ressort conique (110, 110a, 110b) et un support de ressort (120, 220, 320, 720, 5220, 6220) pour recevoir le ressort conique (110, 110a, 110b). Le support de ressort (120, 220, 320, 720, 5220, 6220) comprend une base (121, 221, 321, 721, 5221, 6221), un couvercle d'extrémité (122, 222, 322, 722, 5222, 6222), et une partie de raccordement flexible (123, 223, 323, 723, 5223, 6223) reliée entre eux. Le ressort (110, 110a, 110b) peut être fixé dans le support de ressort (120, 220, 320, 720, 5220, 6220) au moyen d'une pression initiale prédéterminée.
Patent CA-3155961-A1 (CA)
Title: Devices, methods, and systems for priming, separating, and collecting blood components
Inventor: BRIGGS DENNIS
IPC: B04B13/00
Filed: 2016-06-16
Abstract: A photopheresis system (200) is disclosed, and that may be configured to execute one or more protocols. These protocols include: 1) protocols (400; 430, 460) for purging air out of a centrifuge bowl (210) used by the photopheresis system (200); 2) protocols (500; 510 550) for assessing the installation/operation of one or more pressure domes (330) used by the photopheresis system (200); and 3) protocols (580; 600; 660; 700; 740) for collecting buffy coat from blood processed by the photopheresis system (200)
Patent CA-3156772-A1 (CA)
Inventor: BRICOUT DENIS
IPC: A61K47/34
Filed: 2020-11-24
Abstract: A freeze-dried powder for preparing a thermogel comprising: - from 1% to 35% of 2-[(3-aminopropyl)amino]ethanethiol or one of its pharmaceutically acceptable salt; - from 40% to 85% of one or more poloxamer; and - from 0,1% to 20% of one or more carbohydrate compound.
Patent CA-3156783-A1 (CA)
Title: Derive de dihydroimidazopyrimidone tricyclique, son procede de preparation, composition pharmaceutique et son utilisation
Inventor: JIN YUN
IPC: C07D491/20
Filed: 2020-11-09
Abstract: L'invention concerne un composé représenté par la formule générale (I), un isomère cis-trans de celui-ci, un énantiomère de celui-ci, un diastéréoisomère de celui-ci, un racémate de celui-ci, un solvate de celui-ci, un hydrate de celui-ci, ou un sel pharmaceutiquement acceptable de celui-ci ou un promédicament de celui-ci, un procédé de préparation associé, une composition pharmaceutique comprenant le composé et l'utilisation du composé en tant qu'inhibiteur de Lp-PLA2.
Patent CA-3158772-A1 (CA)
Title: Systemes et approches d'administration de medicament
Inventor: POMPE CORNELIUS
IPC: A61M5/142
Filed: 2020-10-23
Abstract: L'invention concerne une approche pour déterminer la compatibilité d'un matériau pour des composants d'un système d'administration de médicament qui consiste à utiliser un procédé analytique à potentiel zêta de surface pour évaluer des interactions de surface entre une molécule souhaitée et au moins un matériau présent dans un système de sac pour perfusion intraveineuse donné.
Patent CA-3159245-A1 (CA)
Title: Compositions et methodes de biorestauration de substrats contenant du glyphosate
Inventor: CANO RAUL DE JESUS
IPC: A62D3/00
Filed: 2020-11-25
Abstract: L'invention concerne de nouvelles formulations de biorestauration et des inocula pour la formulation de formulations de biorestauration. Les formulations de la présente invention comprennent des micro-organismes viables des espèces Paenibacillus xylanexedens, Pseudomonas fluorescens, Bacillus safensis, Streptomyces griseus, Micrococcus luteus, et Bacillus megaterium et peuvent être utilisées pour dégrader des résidus de glyphosate associés à un substrat contaminé par du glyphosate, et corriger ainsi le substrat. Des méthodes associées sont également divulguées.
Patent CA-3161340-A1 (CA)
Title: Appareil et procedes pour rapidement detecter, separer, purifier et quantifier divers virus contenus dans des cellules, un milieu de culture et d'autres liquides
Inventor: ANTOSZCZYK SLAWOMIR
IPC: A61K39/12
Filed: 2020-11-12
Abstract: L'invention concerne des systèmes et des procédés pour la détection, la séparation, la purification et la quantification rapides de particules virales dans un échantillon. Selon certains modes de réalisation, un dispositif microfluidique est prévu pour recevoir l'échantillon qui peut contenir des particules virales. Une électrode du dispositif microfluidique peut être utilisée pour générer des forces diélectrophorétiques (DEP) et/ou électro-osmotiques (EO) agissant sur l'échantillon. Les forces DEP et/ou EO appliquées peuvent immobiliser des constituants de l'échantillon sur la surface de l'électrode, peuvent agréger des particules virales de l'échantillon dans une région du dispositif microfluidique et peuvent séparer d'autres constituants de l'échantillon des particules virales. Les techniques peuvent être réalisées rapidement, par exemple, en huit heures ou moins, et peuvent ne pas affecter l'infectivité des particules virales. Dans certains modes de réalisation, l'échantillon peut être marqué pour améliorer une réponse d'un ou plusieurs des constituants de l'échantillon aux forces DEP et/ou EO.