baber/WOPTO huggingface dataset:
Patent DE-69125024-D1 (DE)
Inventor: XIAO SHAOBO
IPC: C07K7/06
Filed: 1991-11-08
Granted: 1997-04-10
Abstract: This invention consists of two aspects: 1) the method of design and synthesis of LHRH antagonists; 2) the products thereafter obtained by using the above method. Taking (NAc-D2Na1<1>, DpClPhe<2>, D3Pal<3>, Ser<4>, Tyr<5>, DArg<6>, Leu<7>, Arg<3>, Pro<9>, DAla<10>)NH2 as the parent compound, a series of new analogs expressed as (NAc-D2Nal<1>, AA<2>, AA<3>, Ser<4>, AA<5>, AA<6>, Leu<7>, AA<3>, Pro<9>, DAla<10>)NH2 are obtained by fine modification of both lipophilic area and alkaline area of the molecule of the parent compound. In this way, the high antiovulatory activity of the parent compound can be maintained and the histamine releasing activity can be reduced to the level so as to meet the clinical requirement.
Patent DE-69131110-D1 (DE)
Inventor: MOLLER PAUL J
IPC: H04B1/40
Filed: 1991-01-22
Granted: 1999-05-20
Abstract: A unique cellular telephone (100) digitally frequency locks to the received base station transmitter signal. The cellular telephone (100) includes a radio transceiver (106), a reference oscillator (104), and microcomputer (102) with memory therein for controlling the operation thereof. The radio transceiver (106) includes a phase-locked loop (PLL) synthesizer 120, a receiver mixer (122) followed by one or more gain stages (124), a phase detector (126), and a divider (128). The PLL synthesizer (120) generates a signal locked to the reference oscillator (104) that is mixed with the incoming base station transmitter signal in the receive mixer (122) to generate an intermediate frequency signal. The output of the reference oscillator (104) also feeds the divider (128), which divides the reference oscillator signal by an amount so as to generate the divided signal having a frequency substantially the same as the frequency of the intermediate frequency signal from the mixer (122). The output of the divider (128) and the amplified intermediate frequency signal from the amplifier (124) are both fed into the phase detector (126), which generates a binary error signal (110). The microcomputer (102) is responsive to the binary error signal (110) for frequency locking reference oscillator 104 to the received base station transmitter signal. <IMAGE>
Patent DE-69132489-D1 (DE)
Inventor: O'NEILL ROBERT ANDREW
IPC: H01R13/713
Filed: 1991-01-31
Granted: 2001-01-11
Abstract: A cordless electrical appliance, for example an electric hot water jug, has a standard multi-pin type electrical connector on its appliance part (3) and a cooperating connector on the base part. The pins (4,5,6) of the appliance connector (7) are oriented conventionally, namely generally horizontally as for a corded appliance, and are adapted to cooperate with shuttered spring terminals (10,11,12) in the base connector (2), the arrangement being such that as the appliance part (3) is lowered generally vertically onto the base part the horizontal pins (4,5,6) on the appliance connector (7) enter respective apertures in the base connector (2) and displace the shutter (8) thereby enabling the terminal ends of the spring terminals (10,11,12) to move forwards into electrical contact with the ends of the pins (4,5,6) on the appliance part (3). The use of a standard connector arrangement on the appliance part (3) means that the appliance can be used in a corded or cordless manner and has cost advantages. A control on the appliance, eg. an element overtemperature protector on a hot water jug, can be arranged to prevent the base connector (2) from coupling electrically to the base connector (2), and the base connector (2) can advantageously comprise a unitary structure provided with its own cable clamp.
Patent DE-69132516-D1 (DE)
Inventor: SATO YASUE
IPC: H01L21/3205
Filed: 1991-06-03
Granted: 2001-03-01
Abstract: A process for preparing a semiconductor device comprises the step of surface modifying a desired portion of the surface of a substrate and the step of depositing selectively a metal on an electron-donative surface provided corresponding to the portion. <IMAGE>
Patent DE-69133601-D1 (DE)
Inventor: MATKOVICH VLADO I
IPC: A61K35/14
Filed: 1991-05-24
Granted: 2008-09-25
Abstract: A biological fluid processing system (10) for the processing of biological fluid (such as blood) is disclosed. The biological fluid processing system (10) separates gases from the system to improve storage life, safety, and the quality of the processed biological fluid. The biological fluid processing system (10) increases the yield of the processed biological fluid by allowing recovery of biological fluid trapped in various elements of the system. A typical biological fluid processing system (10) includes a collection bag (11) with conduits (12, 15) connecting it to a second container (17) for receiving biological fluid. A functional biomedical device (14) may be included. A gas inlet (13) allows gas to be introduced into the system to recover the biological fluid trapped in the system. A gas outlet (16) allows gas to be purged from the system. <IMAGE>
Patent DE-69209592-D1 (DE)
Inventor: JOERNEUS LARS
IPC: F16B25/00
Filed: 1992-07-07
Granted: 1996-05-09
Abstract: The present invention relates to a screw-shaped titanium anchoring member for permanent anchorage in bone tissue, specifically permanent anchorage of artificial teeth or tooth bridges in the jaw-bone. The tip of the anchoring member comprises at least one cavity (4). The edges of the cavities on the outer cylindrical surface are forming cutting edges (5) to provide self-tapping when the anchoring member is screwed into the bone tissue. The total volume of the cavities is adapted to contain the scraped-off bone tissue material, i.e. all the scraped-off bone tissue material can be housed in the screw in the volume formed by the cavities. Behind the cutting edges (5) the anchoring member has a clearance surface (9), i.e. behind each cutting edge the surface of the anchoring member is slightly bevelled towards the center of the anchoring member. By means of such clearance surface any squeezing effect which might occur in the cutting portion of the fixture when it is screwed into hard bone tissue can be avoided.
Patent DE-69210988-D1 (DE)
Inventor: FASANO FULVIO
IPC: B22D/
Filed: 1992-02-24
Granted: 1996-06-27
Abstract: Multipurpose mould (10) which cooperates with a discharge roller conveyor (13) comprising a first removable segment (14) and can cooperate with an electromagnetic stirrer (21) and also can form part of a plurality of casting lines and includes means (24-25) to control the level of liquid metal, a crystallizer (16), a jacket (18) defining an interspace (50) for the accelerated flow of a cooling fluid, an outer sidewall (19) to form at least one chamber (17) and a closure bottom (22), in which mould (10):   the outer sidewall (19) comprises at least in its second lower part a substantially circular enclosure (20) for the external lodgement of the electromagnetic stirrer (21) supported and positioned on the closure bottom (22); the closure bottom (22) comprises at its lower end positioning and alignment means (34) mating with positioning guide-block supporting means (36) included substantially above the first removable segment (14), and the closure bottom (22) includes in its lower portion attachment means (41) cooperating with connection means (55) comprised substantially above the first removable segment (14).   <IMAGE>
Patent DE-69224898-D1 (DE)
Inventor: NADIM MOHAMMED
IPC: G10K11/178
Filed: 1992-04-09
Granted: 1998-04-30
Abstract: PCT No. PCT/GB92/00642 Sec. 371 Date Dec. 6, 1993 Sec. 102(e) Date Dec. 6, 1993 PCT Filed Apr. 9, 1992 PCT Pub. No. WO92/18975 PCT Pub. Date Oct. 29, 1992.Primary vibrations (N), e.g. acoustic noise or vibration from a source thereof such as a motor, are cancelled by secondary vibrations (C) produced by an actuator (2) driven by a controller (3) that is responsive to an error signal (E) detected by a detector (4) and representative of the residual or difference between the primary and secondary vibrations. The controller samples the error signal (E) during successive sampling periods determined by a synchronising signal (syn) taken from the motor. The secondary vibrations Cn+1 for a sampling period n+1 are determined as follows: Cn+1=Cn- mu EnSGN[1/ &upbar& H], where Cn represents the secondary vibrations produced during a preceding sampling period (n); En represents the detected error signal for said preceding period n, H represents the transfer coefficient between the actuator (2) and the detector (4) and  mu  is a scaling factor where 0</= mu </=1. The apparatus is in one embodiment configured as an add-on unit for a personal computer (PC) including circuit board which fits into an expansion slot of the PC.
Patent DE-69227967-D1 (DE)
Inventor: OHATAKE NORIO
IPC: B22D11/00
Filed: 1992-09-16
Granted: 1999-02-04
Abstract: A cooling method and a cooling mold in a continuous casting wherein even if a continuous casting rate is increased, a proper cooling is carriedout to prevent a danger of a breakout, so as to improve the stability of casting and the high quality of an ingot (4). A cooling mold comprises water cooling jackets (21, 22) which are provided in the inner part of the mold (2), a first cooling water jetting mouth (23) which is arranged at a distance of 20 to 45 mm between a contact position of a primary cooling water and an other contact position of a secondary cooling water on the ingot (2). By use of the cooling mold (2) wherein a primary and a secondary cooling water impinging angles are respectively set at 15 to 30 degrees and at 30 to 60 degrees, the primary cooling water is impinged from the first cooling water jetting mouth (23) to a molten metal (3) which is cooled with the inner surface of the cooling mold (2) to carry-out a primary cooling, and nextly, the secondary cooling water is impinged from the second cooling water jetting mouth (24) to initial zones of a transition boiling zone and a film boiling zone which are produced with the impingement of the primary cooling water, so that a vapor film generated in the transition boiling zoneand the film boiling zone is broken out to provoke a nucleate boiling so as to carry out a direct se condary cooling with the secondary cooling water. <IMAGE>
Patent DE-69231680-D1 (DE)
Inventor: BJOERK ANDERS
IPC: A61P25/32
Filed: 1992-03-23
Granted: 2001-03-15
Abstract: The present invention relates to the relief or prevention of withdrawal syndrome resulting from addiction to non-opiate type drugs of abuse and/or the suppression of dependence on non-opiate type drugs of abuse by administering to a person in need thereof, an effective amount of certain diphenylbutyl-piperazine-carboxamides including 4-[4,4-bis(4-fluorophenyl)butyl]-N-ethyl-1-piperazine-carboxamide which is known as amperozide.
Patent DE-69306761-D1 (DE)
Inventor: TARREGA I LLORET MIGUEL ANGEL
IPC: E05C17/60
Filed: 1993-08-24
Granted: 1997-01-30
Abstract: A mechanism for assembling sliding glass doors, comprising an upper track (3), a lower parallel guide (5) between which are arranged fixed sheets (1) and moveable sheets (2). The track (3) has an inverted L-shaped cross section and its vertical member (6) is provided with means (16) for fastening stops, the lower part of said member ending in an inverted groove (14) with an upper rib (15) on which slides the wheel (30) of the suspension heads which comprise two plates (20 and 21) that can be opposed and fixed together, with the interposition of a pivot (27) to regulate the separation between said plates. The horizontal member (8) of the L-shape is provided at the end with a channel (18) for fixing a shape (19) to restrict the lifting of the sheet (2). <IMAGE>
Patent DE-69307420-D1 (DE)
Inventor: TIEMAN FRANS JAN
IPC: G09B21/00
Filed: 1993-07-07
Granted: 1997-02-27
Abstract: The invention relates to a method of adjusting, in the course of applying predetermined voltages, an oblong piezo-electric bending element (11) which at a first end has been supported by a part (21) protruding in the longitudinal direction of said element, whereby this part is mechanically bent and consists of a material in which at least part of the bending deformation is permanent. In addition, the invention comprises a piezo-electric bending element (11) as has been constructed by applying the method and tools for the application of the method. <IMAGE>
Patent DE-69323922-D1 (DE)
Inventor: LOVE DAVID BRIAN
IPC: B22D11/20
Filed: 1993-04-08
Granted: 1999-04-22
Abstract: A method and apparatus are provided for direct casting molten metal to continuous strip of crystalline material by controlling the supply of molten metal to a casting vessel (18) substantially horizontal to an adjacent moving casting roll surface (24), the molten metal level in the exit end being near the crest of the casting roll, separating a semi-solid cast strip substantially horizontally from near the crest of the casting roll and providing secondary cooling while transporting the separated strip to solidify the strip. <IMAGE>
Patent DE-69329344-D1 (DE)
Inventor: EDELSON L
IPC: A61K35/14
Filed: 1993-11-18
Granted: 2000-10-05
Abstract: Methods and pharmaceutical compositions for modifying the immune response of a mammal to a specific antigen are provided. The methods include treating an antigen presenting cell to enhance expression of a major histocompatibility complex molecule and reacting the treated antigen presenting cell with the antigen extracorporeally to form an antigen-associated antigen presenting cell.
Patent DE-69329538-D1 (DE)
Inventor: SCHERZ AVIGDOR
IPC: A61K47/48
Filed: 1993-07-26
Granted: 2000-11-16
Abstract: Conjugates of chlorophyll (Chl) and bacteriochlorophyll (Bchl) derivatives with amino acids, peptides and proteins are provided by the invention.The amino acid, peptide or protein residue is linked to the 17-propionic acid group of a Chl or Bchl residue directly or through a chain.The conjugates are for use as photosensitizers in photodynamic therapy and in diagnostics of tumors. Conjugation with cell-specific ligands, such as hormones, growth factors or tumor-specific antibodies, will target the Chl or Bchl moiety to the tumor site. Thus, conjugates with melanocyte stimulating hormones are suitable for photodynamic therapy of melanoma tumors.
Patent DE-69331054-D1 (DE)
Inventor: GALAND CLAUDE
IPC: H04L12/56
Filed: 1993-07-30
Granted: 2001-12-06
Abstract: The object of the invention is to perform an automatic decomposition of a packet switching network in backbone nodes and subareas nodes to speed up the routing path search without degrading the optimization criterion of the routing algorithm and without generating additional control messages on the network. Currently, routing algorithms compute all the available paths in the network, from the source node to the destination node before to select an optimal route. However, networks are rarely fully meshed. They are usually built around a hierarchical structure : a set of nodes, interconnected by high throughput lines, are used to build a backbone with a high degree of meshing and then, local nodes are grouped in geographical subareas themselves attached to the backbone. Routing algorithms can take advantage of this particular network topology to drastically reduce the complexity of paths computation. For a given connection, only a limited number of nodes are defined as usable and are taken in account by the algorithm in its path calculation. <IMAGE>
Patent DE-69333672-D1 (DE)
Inventor: NIELSEN EGON
IPC: C11D3/386
Filed: 1993-12-22
Granted: 2004-11-25
Abstract: PCT No. PCT/DK93/00441 Sec. 371 Date Jun. 15, 1995 Sec. 102(e) Date Jun. 15, 1995 PCT Filed Dec. 22, 1993 PCT Pub. No. WO94/14951 PCT Pub. Date Jul. 7, 1994The present invention relates to lipase and  alpha -amylase variants, stabilized towards the inactiviation caused by peroxidase systems, in which variants a naturally occurring tryosine residue has been deleted, substituted with a different amino acid residue at one or more positions. The invention also relates to a method of stabilizing a lipase or an  alpha -amylase towards the inactivation caused by the preoxidase systems, and detergent compositions comprising a lipase and/or  alpha -amylase variant of the invention.
Patent DE-69402092-D1 (DE)
Inventor: OLIVER WARD HOPKINS
IPC: C07C261/04
Filed: 1994-02-10
Granted: 1997-04-24
Abstract: 1-Amino-1-cyanamido-2,2-dicyanoethylene, sodium salt is prepared by a process which comprises reacting malononitrile with sodium dicyanamide at an elevated temperature and in the presence of an aprotic, dipolar solvent. The subject compound is useful as an intermediate to prepare substituted pyrimidines.
Patent DE-69410161-D1 (DE)
Inventor: EMIN MICHEL
IPC: G01F23/296
Filed: 1994-03-15
Granted: 1998-06-18
Abstract: The invention relates to an apparatus for measuring the level of an interface (1) in a liquid (L) laden with particles in suspension. This apparatus includes a measuring bell (10) defining an internal volume (12), open to the bottom, in the liquid, an interface level sensor (C) known per se, suitable for taking interface level measurements in the said liquid across a measurement surface (14) emerging into the said internal volume (12) and means for moving the level of the liquid in the bell for the purpose of keeping the measurement surface outside the said liquid during periods when the sensor is not in use and in contact with the said liquid when the sensor is in use. <IMAGE>
Patent DE-69413892-D1 (DE)
Inventor: SAKAKI MAMORU
IPC: B41M5/50
Filed: 1994-07-14
Granted: 1998-11-19
Abstract: In a method of manufacturing and storing a recording sheet (25), a coating solution is coated on at least one surface of a base member (25-1) and dried and a resulting recording sheet is cut and enclosed in a packaging material. The process from drying to enclosing is carried out in an atmosphere having a humidity not exceeding 50 %RH. <IMAGE>
Patent DE-69413979-D1 (DE)
Inventor: LEE SHUEH-MO
IPC: B29C65/66
Filed: 1994-07-15
Granted: 1998-11-19
Abstract: A process for manufacture of an automotive trim piece having a polymeric skin fastened to substrate. The polymer, for example, polyvinyl chloride has the property that upon cooling to a relatively rigid state the polymer shrinks. The process includes a step of molding the polymeric skin separately from the substrate such that the skin has a rear face for abutment with an obverse face of the substrate and a pair of lips extending from ends of the rear face. The lips are configured for engaging corresponding edges of the substrate. The skin is cooled to a relatively elastic state, and the skin and substrate are assembled while the skin is in the relatively elastic state. On further cooling, shrinkage forces of the skin and the skin lips in abutment with the corresponding edges of the substrate produce a snug fit from edge to edge of the skin to the substrate and the skin becomes relatively rigid.
Patent DE-69429013-D1 (DE)
Inventor: UPMEYER HANS-JUERGEN
IPC: A61K47/24
Filed: 1994-12-02
Granted: 2001-12-13
Abstract: The invention disclosed relates to the use of dimeticone as an agent for treating constipation.
Patent DE-69432472-D1 (DE)
Inventor: SCHREIBER ALAN D
IPC: C12N15/113
Filed: 1994-09-30
Granted: 2003-05-15
Abstract: The present invention relates, in general, to methods of treating diseases resulting from interactions between immune complexes and Fc receptors. In particular, the present invention relates to methods of modulating the clearance of antibody-coated cells from the circulation by inhibiting phagocytosis and to methods of modulating the interaction of immune complexes with tissue Fc receptors. Further, the invention relates to methods of modulating the activation of immunological processes mediated by Fc receptor activation resulting from antibody-antigen/receptor interaction.
Patent DE-69509192-D1 (DE)
Inventor: SUTHERLAND ROBERT
IPC: B65D71/44
Filed: 1995-02-27
Granted: 1999-05-27
Abstract: A carrier especially suited for carrying beverage cans. The carrier is comprised of a top panel connected to support panels which contain slots for receiving the can chimes. In addition, short side panel flaps connected to the support panels and end panel flaps connected to the top panel assist in holding the cans in place. Webs foldably connected to the side panel flaps and to extensions of the end panel flaps cause the end panel flaps to be automatically drawn into place. The side panel flaps, the webs and the end panel extensions are glued together to hold the carrier in locked condition.
Patent DE-69512816-D1 (DE)
Inventor: TAKADA SUSUMU
IPC: C07D401/04
Filed: 1995-04-07
Granted: 1999-11-25
Abstract: An oxopyridinylquinoxaline derivative represented by the following Formula I or pharmaceutically acceptable salts thereof: <CHEM> wherein R<1> is hydrogen, halogen, nitro, or trihalomethyl; R<2> is hydrogen, halogen, nitro, cyano, trihalomethyl, carbamoyl, carbamoyl substituted with lower alkyl, sulfamoyl, or sulfamoyl substituted with lower alkyl; R<3> is hydrogen, nitro, or halogen; R<4> is hydrogen, lower alkyl, substituted lower alkyl, lower cycloalkyl, or substituted lower cycloalkyl; R5's are substituents independently selected from the group consisting of halogen, nitro, cyano, lower alkyl, carbamoyl, and carbamoyl substituted with lower alkyl; and n is an integer of 0 to 4. The derivative works as an antagonistic agent against both the NMDA receptors and the AMPA receptors, so that it is effective as a therapeutic agent for neurological disorders caused by excitatory amino acids binding to the receptors.
Patent DE-69522972-D1 (DE)
Inventor: SIVIK MARK ROBERT
IPC: C07C217/08
Filed: 1995-07-13
Granted: 2001-10-31
Abstract: The present invention relates to novel antioxidant compounds to reduce the physical or chemical degradation or discoloration of surfaces, especially the fading of a variety of surfaces from sunlight, wherein the antioxidant compound is a derivative of butylated hydroxytoluene or sorbic acid and is selected from the group consisting of: <CHEM>   <CHEM>  wherein   each    R<7> is selected from the group consisting of a saturated or unsaturated C1-C22, alkyl, aryl, cyclic alkyl group (which may be interrupted by an ester, amide, or ether group), hydrogen, and mixtures thereof; each    R<8>, and R<9> is selected from the group consisting of a saturated or unsaturated C1-C22, alkyl, aryl, cyclic alkyl group (which may be interrupted by an ester, amide, or ether group), and mixtures thereof;   n is from 1 to 50;   Z is a hydrogen or a methyl group; wherein the amino group of the compounds of Formulas I to II can be protonated or quaternized with R<10>X where R<10> is a hydrogen, a C1-C6 alkyl group, C1 -C6 hydroxyl alkyl group, benzyl group and mixtures thereof; and X<-> is any compatible anion.
Patent DE-69600584-D1 (DE)
Inventor: BONI ROMANO
IPC: B65H59/38
Filed: 1996-05-03
Granted: 1998-10-08
Abstract: A textile machine for forming yarn windings (36) of any shape comprising a frame, a feed of yarn to be treated, a support element (20), provided with a motor (21) for its rotation, for collecting and winding treated yarn, a thread guide (35) for distributing the yarn (14) along the support element (20), at least one roller (12,13), provided with a motor (16,17) for its rotation, which receives yarn from the yarn feed and feeds it to the collecting support element (20) via the thread guide (35) , and a sensor (24) positioned between the at least one roller (12,13) and the support element (20) for collecting the treated yarn (14), in which machine the sensor (24) senses the braking force generated by the at least one roller (12,13) on the yarn being wound on the support element (20), and is connected to a processor (25) which compares the measured braking force with a preset force, and varies the rotational speed of the motor (16,17) of the at least one roller (12,13) to adjust the previously measured braking force to the preset value by increasing the rotational speed of the roller (12,13) if the measured braking force is greater than the preset value, and decreasing the rotational speed of the roller (12,13) if the measured braking force is less than the preset value. <IMAGE>