baber/WOPTO huggingface dataset:
Patent EP-3512527-A2 (EP)
Inventor: AIKAWA ELENA
IPC: C12N15/113
Filed: 2017-09-12
Abstract: Provided herein are methods for reducing levels of blood cholesterol, low-density lipoprotein (LDL), and/ or the treatment of diseases associated with high cholesterol, hyperlipidemia, dyslipidemia, or high levels of low-density lipoprotein (LDL), wherein the methods comprise administering a DRP1 inhibitor to a subject in need thereof. In certain embodiments, the subject is selected for treatment as described herein when the subject exhibits intolerance to conventional statin therapy. Also contemplated herein are the use of DRP1 inhibitors in the treatment of cancer and inflammatory disease.
Patent EP-3354794-A2 (EP)
Inventor: DE BRUIJN PETER ANTONIUS MARIA
IPC: E01C3/00
Filed: 2018-03-23
Abstract: Support layer (1) for supporting an artificial turf assembly (30), said support layer being formed of a polymeric foam, preferably having a density of between 20 and 70 gram per liter, such as a polyolefin foam; and having an upper side (2) and a lower side (3), wherein in use the support layer (1) has been placed with the lower side (3) thereof on a base surface and supports, on the upper side (2) thereof, the artificial turf assembly, the support layer (1) comprising a plurality of through drainage holes (6) extending from the upper side (2) to the lower side (3) for allowing liquid such as rain water to flow via the plurality of drainage holes (6) from the upper side (2) to the lower side (3), and also comprising a plurality of channels (4) at the lower side (3) for allowing liquid such as rain water to flow through the channels (4) along the lower side (3), wherein each of said plurality of drainage holes (6) debouches into one of the plurality of channels (4). The application also relates to an artificial turf system (50), comprising an artificial turf assembly (30) and the present support layer (1) supported on a base surface (32) such as a layer of sand, wherein the support layer (1) forms, at the upper sides (2) thereof, a closed support surface supporting the artificial turf assembly (30).
Patent EP-3401638-A2 (EP)
Inventor: OHTOMO FUMIO
IPC: G01C15/00
Filed: 2018-05-04
Abstract: A target instrument has an illuminating lamp, wherein a total station has an optical axis deflector capable of deflecting a distance measuring optical axis, a projecting direction detecting module for performing an angle measurement of the distance measuring optical axis, an image pickup unit, and an arithmetic control module for controlling a deflecting action of the optical axis deflector and a distance measuring action of a distance measuring unit, wherein the arithmetic control module is configured to detect an illumination light from an image acquired by the image pickup unit, to acquire a direction of the illuminating lamp based on a detection result, to make the optical axis deflector to scan with a distance measuring light around the acquired direction and to perform a distance measurement and an angle measurement along a scanning path.
Patent EP-3604334-A2 (EP)
Inventor: MOON KYUNG DUK
IPC: G01N33/574
Filed: 2018-03-21
Abstract: The present invention relates to an anti-MUC1 antibody binding specifically to Mucin 1 (MUC1) and a use thereof and, more particularly, to an anti-MUC1 antibody or an antigen-binding fragment thereof, an antibody-drug conjugate or bispecific antibody comprising the antibody or an antigen-binding fragment thereof, a pharmaceutical composition for prevention or treatment of cancer, comprising the same conjugate or bispecific antibody, and a nucleic acid encoding the same antibody or an antigen-binding fragment thereof, a vector and a host cell, both carrying the same nucleic acid, and a method for preparing an anti-MUC1 antibody or an antigen-binding fragment thereof, using the same vector and host cell. According to the present invention, an antibody binding specifically to MUC1 or an antigen-binding fragment thereof shows outstanding affinity and binding force to MUC1 and an antibody-drug conjugate in which the antibody or an antigen-binding fragment thereof is conjugated with a drug can bind specifically to a MUC1-expressing cell to specifically or selectively transfer the drug with efficacy. Therefore, the anti-MUC1 antibody and the antibody-drug conjugate according to the present invention can be usefully applied to the treatment of a MUC1-related disease, for example, cancer.
Patent EP-3537149-A2 (EP)
Title: Antrieb, schienenfahrzeug und verfahren zum verbessern des schmiermitteleinsatzes in einem antrieb eines fahrzeugs
Inventor: CEPAK WERNER
IPC: G01N33/28
Filed: 2019-03-05
Abstract: Antrieb, Schienenfahrzeug und Verfahren zum Verbessern des Schmiermitteleinsatzes in einem Antrieb eines FahrzeugsDie Erfindung betrifft Verfahren zum Verbessern des Schmiermitteleinsatzes in einem Antrieb (30) eines Fahrzeugs,wobei der Antrieb (30) einen elektrischen Traktionsmotor (1) umfasst und wenigstens Bereich mit Schmiermittel, wobei das Verfahren umfasst:- Ermitteln einer Schmiermitteltemperatur (T);- Abschätzen einer noch verfügbaren Gebrauchsdauer und/oder eines bereits verbrauchten Anteils der zulässigen Gebrauchsdauer des Schmiermittels basierend auf der Schmiermitteltemperatur (T).Ferner betrifft die Erfindung einen Antrieb (30) zum Antreiben eines Fahrzeugs, der einen verbessertem Schmiermitteleinsatz ermöglicht, und ein Schienenfahrzeug umfassend einen solchen Antrieb (30).
Patent EP-3557143-A2 (EP)
Inventor: Rosén Per
IPC: F24F5/00
Filed: 2016-11-02
Abstract: The present invention relates to a thermal energy consumer controller (28) arranged to selectively control the use of either a thermal energy consumer valve (23) or a thermal energy consumer pump (24) based on differential pressure. The present invention relates to a thermal energy generator controller (38) arranged to selectively control the use of either a thermal energy generator valve (33) or a thermal energy generator pump (34) based on differential pressure.
Patent EP-3611362-A2 (EP)
Inventor: N KOTI ARCHIT
IPC: B60W30/14
Filed: 2019-07-26
Abstract: A vehicle (10) comprises an aftertreatment system (150) configured to reduce constituents of an exhaust gas. The vehicle also includes a controller (170) configured to determine a predicted load on the vehicle during a route, and adjust at least one of a temperature of the aftertreatment system or an amount of a reductant inserted into the aftertreatment system based on the predicted load.
Patent EP-3640341-A2 (EP)
Inventor: GUO WEI
IPC: C12Q1/6886
Filed: 2016-02-24
Abstract: Methods are provided for determining a genomic methylation profile in a DNA sample. In certain aspects, the methods can be used to determine if a subject has, or is at risk for developing, a bladder cancer or other cancers of the urinary tract. Methods for treatment of such subjects are likewise provided.
Patent EP-3613359-A2 (EP)
Inventor: HARRIS JASON L
IPC: A61B17/072
Filed: 2019-08-19
Abstract: An anvil for a surgical stapler. The anvil includes a staple-forming undersurface that has lines of staple-forming pockets that are configured to establish a flexible staple line. A plurality of anvil protrusions protrude from planar non-forming surface portions such that each anvil protrusion is adjacent to at least two staple-forming pockets to direct staples therein during a staple firing process and to engage the tissue that is being stapled.
Patent EP-3650904-A2 (EP)
Inventor: KI HO KYUNG
IPC: G02B19/00
Filed: 2019-11-06
Abstract: Disclosed herein is a light diffusion lens. The light diffusion lens according to one embodiment of the present disclosure includes a bottom surface, an incidence surface concavely formed inward the bottom surface from one area (an incidence hole) thereof, and an exit surface from which light incident through the incidence surface is emitted, wherein at least two dimples are formed on the incidence surface symmetrically in relation to an optical axis.
Patent EP-3660792-A2 (EP)
Inventor: SHTIRBERG ILLYA
IPC: G06T19/20
Filed: 2019-11-12
Abstract: A system including a medical device to form a 3D image of an anatomical structure in a body of a living subject, a user interface including a display and an input device, and a processor to prepare a user interface screen presentation including a graphical representation of the anatomical structure based on the 3D image, generate a feature list of a plurality of features associated with the anatomical structure, each feature having a respective location, render the user interface screen presentation to the display showing a first view of the graphical representation, receive an input from the user interface selecting a feature from the list, and render the user interface screen presentation to the display showing the graphical representation of the anatomical structure being automatically rotated from the first view to a second view showing the selected feature at the respective location on the graphical representation.
Patent EP-3857004-A2 (EP)
Inventor: BISSELING JACOBUS PETRUS JOHANNES
IPC: E02D5/60
Filed: 2019-09-25
Abstract: When repairing or reinforcing a wooden pole (1) that is at least partly present under water (3), first, a casing (5) is arranged around an affected part (7) of the pole. Subsequently, on the underside of the casing, the space (9) between the casing (5) and the pole (1) is sealed and then this space (9) between the casing (5) and the said part (7) of the pole (1) is filled with an epoxy (11). When applying the casing (5) around the pole (1), first a casing part open on one side with a U-shaped cross section is slid in a direction perpendicular to the longitudinal direction of the post (1), and then closed with a plate (14) the open side of the casing part (5a) wherein the plate is attached to the side edges of the casing part.
Patent EP-3815154-A2 (EP)
Title: A neuron circuit
Inventor: BOZBEY ALI
IPC: G06N3/02
Filed: 2019-06-27
Abstract: The present invention relates to a neuron circuit (1), which electronically applies the working principle of the neurons in human brain, controls an input signal according to a set threshold value, and enables to provide an output signal above the threshold value.
Patent EP-3889296-A2 (EP)
Inventor: KIM SANG HO
IPC: C22C38/04
Filed: 2019-11-29
Abstract: The present invention relates to a structural steel sheet suitable for ships or steel structures and, more particularly, to a high-strength steel sheet having excellent ductility and low-temperature toughness and a method for manufacturing same.
Patent EP-3708087-A2 (EP)
Inventor: RAY MARK
IPC: A61B6/03
Filed: 2020-03-12
Abstract: Provided is an imaging device (16) including a body (40), an x-ray detector assembly (42) attached to the body (40), and an x-ray source assembly (44) attached to the body (40). The x-ray detector assembly (42) includes a telescopic actuator (92) movable between a retracted position and an extended position, and an x-ray detector (90) attached to the telescopic actuator (92).
Patent EP-3792536-A2 (EP)
Title: Negative pressure pipeline opening and closing device
Inventor: CHEN LIGUO
IPC: F16K31/22
Filed: 2020-09-09
Abstract: A negative pressure pipeline opening-and-closing device includes a blocking member and a buoyant member. The buoyant member comprises two floats and a connection rod connected to the two floats. The liquid reservoir is provided with a guide therein, and the guide confines the two floats, the blocking member and the liquid outlet port in the same vertical line. A limiting member is arranged between the two floats and is fixed to an inner wall of the liquid reservoir. A maximum distance between the limiting member and a top wall of a lower float of the two floats is smaller than a maximum distance between a top wall of an upper float of the two floats and a top wall of the liquid reservoir. The negative pressure pipeline opening-and-closing device can replace an existing electrically controlled valve. Therefore, the cost is reduced, the maintenance is convenient and service life is prolonged.
Patent EP-3921651-A2 (EP)
Inventor: BONI GERARDO ARREVILLAGA
IPC: G01N33/68
Filed: 2020-02-05
Abstract: The technology relates in part to methods for detecting of Meteorin-β and modified versions thereof.
Patent EP-3874464-A2 (EP)
Inventor: SCHIED CHRISTOPH HERMAN
IPC: G06T15/00
Filed: 2020-02-13
Abstract: Embodiments disclosed herein relate to a graphics processing chip for rendering computer graphics. The graphics processing chip may include a controller configured to manage operations of the graphics processing chip in accordance with a graphics-rendering pipeline. The operations may include geometry-processing operations, rasterization operations, and shading operations. The chip may further include programmable memory components configured to store a machine-learning model configured to perform at least a portion of the shading operations. The chip may also include a plurality of processing units configured to be selectively used to perform the shading operations in accordance with the machine-learning model. The chip may also include at least one output memory configured to store image data generated using the shading operations.
Patent EP-3939020-A2 (EP)
Inventor: RANGAN SURESH
IPC: G08B21/06
Filed: 2020-03-13
Abstract: An in-flight risk management system includes an eye sensor, a seat sensor, and one or more in-flight risk management computers that perform operations including: obtaining history information for a flight crew member, obtaining flight information associated with a flight on which the flight crew member will be present, determining, based on the history information and the flight information, a predicted fatigue profile for the flight crew member, determining, based on the predicted fatigue profile for the crew member, one or more fatigue indicator profiles for the flight crew member, obtaining, from at least one of the eye sensor or seat sensor, one or more measured fatigue indicator values associated with the flight crew member, generating, based on the one or more measured fatigue indicator values, one or more updated fatigue indicator profiles, and generating, based on the one or more updated fatigue indicator profiles, an updated predicted fatigue profile.
Patent EP-3931592-A2 (EP)
Inventor: STEVENSON MATTHEW A
IPC: G01S13/02
Filed: 2020-02-24
Abstract: This disclosure enables various technologies for determining space object attitude stabilities from radar cross-section statistics. In particular, such determinations can be made via employing various phased-array radars with various fields of views, which can monitor various space objects (e.g., satellites, space debris, rocket bodies, space stations) over various periods of time (e.g., minutes, hours, days, weeks, months) as the space objects come into the fields of views. For example, a technique for estimating attitude stability of low-Earth RSOs using RCS statistics from various radars (e.g., group of radars, phased-array radar network). Assuming a non-isotropic shape, an Earth-oriented RSO can have an elevation-angle dependent RCS when viewed from a ground-based radar. Therefore, an RSO attitude stability can be tested by looking for a difference in a median or mean RCS when the RSO is viewed at different elevation angles.
Patent EP-4065007-A2 (EP)
Inventor: SHARON ASSAF
IPC: A61B17/04
Filed: 2020-12-21
Abstract: An implant (20) comprises a wall (28) that surrounds a lumen (44). A delivery tool (8) comprises a catheter (22), a control assembly (64), and an ultrasound tool (36). The catheter is transluminally advanceable into a subject, and has a distal opening. The implant can be delivered via the catheter. The control assembly can advance at least a portion (70) of the wall out of the distal opening, and can steer the catheter to place the portion against a site of a tissue of the subject, the site disposed distally from the portion and opposite the distal opening. The ultrasound tool can (i) position an ultrasound transceiver within the lumen and facing the portion, and (ii) facilitate imaging of the site by transmitting ultrasound energy through the portion. An anchor driver can anchor the implant to the tissue by driving an anchor through the portion and into the site.
Patent EP-4038102-A2 (EP)
Inventor: WILLIAMS SYBIL M G
IPC: C07K14/705
Filed: 2020-09-29
Abstract: Novel methods for selecting a patient with a cancer for treatment with a TIGIT antagonist are disclosed. The methods employ various biomarkers, including CD45, CD3ε, CD11b, Foxp3, IFN-γ, Cxcl11, Cxcl10, TNF-α, IL-23, MHC class II, CD80, CD86, and CD40.
Patent EP-3916766-A2 (EP)
Title: Verfahren zur kontrolle von handlingssystemen
Inventor: BIRKNER ANDREAS
IPC: G06K9/46
Filed: 2021-05-05
Abstract: Die Erfindung betrifft ein Verfahren zur Kontrolle von Handlingsystemen, wobei ein rechnerunterstütztes Verfahren zum Bestimmen der Präsenz und/oder der Position und/oder der Orientierung eines Objektes, umfassend ein Substrat, ein Wafer, eine Maske, ein Flat Panel Display, eine Auflage, eine Kassette, eine Bearbeitungsstation oder eine Maschine, zur Anwendung kommt. Die Erfindung betrifft ferner ein zur Ausführung des Verfahrens ausgebildetes System. Das rechnerunterstützte Verfahren kann dabei ein künstliches neuronales Netz umfassen.
Patent EP-3968055-A2 (EP)
Inventor: KANA ZDENEK
IPC: G01S19/54
Filed: 2021-07-05
Abstract: Systems and methods for estimating attitude and heading are provided. The systems and methods utilize carrier phase single difference (CSD) measurements or carrier phase double difference (CDD) measurements and a validation test for CSD or CDD measurement residuals. The systems and methods include applying a wrapping function with limit of ±half of the GNSS carrier signal wavelength to CSD or CDD measurement residuals to generate refined CSD or CDD measurement residuals and validating the refined CSD or CDD measurement residuals variance to determine valid CSD or CDD measurements. By using the validated CSD and CDD measurements, the systems and methods enable low grade hybrid inertial navigation systems to estimate attitude and heading with integrity and without a magnetometer or the need for integer ambiguity resolution even during the static or steady phases of flight/operation.
Patent EP-4114431-A2 (EP)
Title: Peptides antiviraux dirigés contre le sars-cov-2 structuralement stabilisés et leurs utilisations
Inventor: WALENSKY LOREN D
IPC: A61K38/10
Filed: 2021-03-04
Abstract: L'invention concerne des peptides réticulés utiles pour interférer avec une infection à coronavirus (par exemple, une infection par le SARS-CoV -2) et inhiber cette dernière. L'invention concerne ainsi des méthodes de traitement et/ou de prévention d'une infection par le coronavirus (par exemple, la COVID-19).
Patent EP-4142766-A2 (EP)
Inventor: WALENSKY LOREN D
IPC: A61K38/03
Filed: 2021-04-27
Abstract: Disclosed herein are peptides and structurally-stabilized peptides that selectively bind to HDMX, or both HDMX and HDM2 as well as compositions comprising the same. Also provided are methods for using such peptides in the treatment and diagnosis of cancer (e.g., HDMX-expressing and/or -dependent cancers).
Patent EP-4307547-A2 (EP)
Inventor: WANG LEI
IPC: H02M3/158
Filed: 2021-08-05
Abstract: A control method for a synchronous BUCK circuit is disclosed, including: obtaining an input voltage, an output voltage and an output current of the synchronous BUCK circuit; obtaining a current state of the synchronous switch transistor; obtaining a turn-off current threshold when the synchronous switch transistor is in an on state; switching the synchronous switch transistor to an off state when the output current is less than the turn-off current threshold; calculating a duty ratio of a main switch transistor according to the input voltage, the output voltage and the turn-off current threshold; and generating a corresponding driving signal according to the duty ratio, to control the synchronous BUCK circuit.
Patent EP-4200821-A2 (EP)
Title: Photo-capacitance sensor
Inventor: NATHAN AROKIA
IPC: G06V40/13
Filed: 2021-08-18
Abstract: A photo-capacitance sensor (29) includes an input surface (30) and one or more light sources (31) arranged to illuminate a portion (35) of the input surface (30). The photo- capacitance sensor (29) also includes an array (36) of photo-capacitors arranged (32) to receive light (38) from the one or more light sources (31) which is reflected from an object (39) in contact with, or proximate to, the illuminated portion (35) of the input surface (30). The array (36) of photo-capacitors (32) is configured for detecting a reflective pattern of the object (39).
Patent EP-4192956-A2 (EP)
Title: Human xist antisense oligonucleotides for x reactivation therapy
Inventor: LEE JEANNIE T
IPC: C12N15/113
Filed: 2021-08-05
Abstract: Antisense Oligonucleotides targeting XIST RNA, and the use thereof for reactivating genes on the inactive X chromosome.
Patent EP-4135020-A2 (EP)
Title: Bond pads for semiconductor die assemblies and associated methods and systems
Inventor: BHUSHAN BHARAT
IPC: H01L23/00
Filed: 2022-08-11
Abstract: Bond pads for semiconductor die assemblies, and associated methods and systems are disclosed. In one embodiment, a semiconductor die assembly includes a first semiconductor die including a first bond pad on a first side of the first semiconductor die. The semiconductor die assembly further includes a second semiconductor die including a second bond pad on a second side of the second semiconductor die. The first bond pad is aligned and bonded to the second bond pad at a bonding interface between the first and second bond pads, and at least one of the first and second bond pads include a first metal and a second metal different than the first metal. Further, the first metal is located at the bonding interface and the second metal has a first thickness corresponding to at least onefourth of a second thickness of the first or second bond pad.
Patent EP-4203549-A2 (EP)
Title: Technologies for network path and topology management
Inventor: SRIVASTAVA AMAR
IPC: H04L5/00
Filed: 2022-10-26
Abstract: The present disclosure relates to techniques for determining optimal routing paths for computing devices in a network, including selecting an optimal gateway among a number of available gateways. The techniques include gathering data regarding characteristics of a network, including gateways and network access nodes (NANs) in at least one access network. The characteristics can include, e.g., supported frequency bands, communication protocols, signal-to-noise ratio, power, signal noise and quality, slicing information, and whether a network vender is a standalone network vendor or a non-standalone network vendor. In one aspect, the characteristics are obtained using the Mobile Broadband Interface Model (MBIM). The characteristics can be used by devices in determining routing paths based on requirements of individual flows and/or workflows of individual application instances.
Patent EP-4300696-A2 (EP)
Title: Separator, method of manufacturing separator, and electrochemical device including separator
Inventor: LEE CHANG HEE
IPC: H01M50/403
Filed: 2023-06-09
Abstract: The present invention relates to a separator, a method of manufacturing the separator, and an electrochemical device including the separator. According to an exemplary embodiment of the present invention, a separator includes: a porous substrate; and an inorganic particle layer provided on at least one surface of the porous substrate, wherein the inorganic particle layer includes inorganic particles and a hydrolytic condensate of a silane compound, and the separator satisfies the following Relation (1):        T   1     −     T   0     ≥   30   %        wherein T 0  is a light transmittance measured by allowing the separator to stand at 25°C for 1 hour and then vertically spacing the separator apart from a halogen lamp with a rated voltage of 12 V and a power consumption of 50 W by 100 mm, and T 1  is a light transmittance measured by allowing the separator to stand at 150°C for 1 hour and then vertically spacing the separator apart from a halogen lamp with a rated voltage of 12 V and a power consumption of 50 W by 100 mm.