baber/WOPTO huggingface dataset:
Patent CA-2994162-A1 (CA)
Inventor: SLUSHER BARBARA
IPC: A61K31/7076
Filed: 2016-07-29
Abstract: The presently disclosed subject matter relates to methods, uses, and pharmaceutical compositions comprising at least one glutamine antagonist, or a prodrug or analog thereof, for the treatment of cognitive deficits, such as those associated with neurological or neurodegenerative disorders, psychiatric or mood disorders, and HIV-associated neurocognitive disorders (HAND)). The presently disclosed subject matter provides supporting PK and biomarker data. These data predict the use of glutamine antagonists (or their prodrugs or analogs) for the treatment of cognitive deficits in general, and specifically for cognitive deficits associated with neurological or neurodegenerative disorders, psychiatric or mood disorders, and HAND.
Patent CA-2994266-A1 (CA)
Inventor: RABER JEFFREY CHARLES
IPC: G01N30/88
Filed: 2016-07-30
Abstract: The disclosure provides a method for extracting, separating, and identifying compounds from natural products, such as cannabis or hops, where separation uses gas chromatography (GC). The method includes spiking the composition to be identified with at least two markers that bracket the migration position of at least one of the compounds to be identified, where GC method uses more than one ramping step.
Patent CA-2996021-A1 (CA)
Title: Tower for a wind turbine
Inventor: DREWES STEPHAN
IPC: F03D13/20
Filed: 2016-09-08
Abstract: The invention relates inter alia to a tower for a wind turbine, with an upper tower portion (2) and a lower tower portion (4, 4'), wherein the upper tower portion (2) comprises a tubular tower (6), wherein the lower tower portion (4, 4') comprises a lattice tower (8, 8'). The object of allowing improved ergonomics and work safety and making it possible to obtain a structural design with optimized forces is achieved by the lower tower portion (4, 4') comprising a central tube (10, 10') arranged centrally within the lattice tower (8, 8'), and by the central tube (10,') having a smaller diameter, at least in certain portions, than at least part of the tubular tower of the upper tower portion.
Patent CA-2996847-A1 (CA)
Title: Dunnage conversion system and method for expanding pre-slit sheet stock material
Inventor: CHEICH ROBERT C
IPC: B31D5/00
Filed: 2016-06-24
Abstract: A dunnage conversion machine (12) includes a frame (20), a supply support (22) coupled to the frame for supporting a supply of expandable sheet stock material (16), and a pair of opposed expansion members (69, 70) rotatably coupled to the frame for rotation about respective axes. The expandable sheet stock material is gripped between the expansion members while it is drawn between the expansion members. Tension provided between a downstream pulling force downstream of the expansion members and the gripping force of the expansion members causes expansion of the expandable sheet stock material. Portions of the expansion members are periodically recessed.
Patent CA-2997348-A1 (CA)
Inventor: PETRASHOV VICTOR TIKHONOVICH
IPC: G01R33/035
Filed: 2016-08-26
Abstract: A quantum interference device comprising a superconducting loop interrupted by a normal conductor segment, and an interferometer connected to the normal conductor segment wherein the superconducting loop comprises a plurality of turns. The turns can be a plurality of adjacent lobes. A coil can be located within a lobe of the superconducting loop. Optionally a bridge layer (e.g. of gold) is formed above the substrate to make an electrical contact between a superconducting layer (e.g. of niobium) formed above the bridge layer and a normal conducting layer (e.g. of titanium) formed above the bridge layer. The bridge layer allows the device to be formed of superconducting and normal conducting materials that are otherwise incompatible. A titanium normal conducting layer can be allowed to oxidise over a period of years.
Patent CA-2998986-A1 (CA)
Inventor: ELSON ANDREW CHARLES
IPC: B64C3/24
Filed: 2016-09-19
Abstract: An aerofoil has at least one space frame and at least one pre-stressed cover supported by the space frame. The space frame has one or more structural members, the structural members including a structural foam material; and the pre-stressed cover forms at least a part of an external aerodynamic surface of the aerofoil.
Patent CA-2999347-A1 (CA)
Title: Diminution de la teneur en acide gras sature de graines de plante
Inventor: MERLO ANN OWENS
IPC: A01H5/00
Filed: 2011-06-24
Abstract: Des compositions et des procédés comprennent le codage génétique et lexpression de nouveau désaturase delta-9 dans des cellules végétales. Dans certains modes de réalisation, il y a des procédés dexpression dacides nucléiques dans une cellule végétale pour bénéficier de lactivité de lenzyme de désaturase delta-9, de telle sorte que la composition en pourcentage dacides gras saturés dans des semences de plante diminue, et quil y a une augmentation concomitante dacides gras oméga-7. Dans dautres modes de réalisation, des séquences dacides aminés ont une activité de désaturase delta-9. Des procédés peuvent impliquer lexpression de désaturase delta-9 dans des cellules végétales, des matières végétales et des plantes entières de façon à augmenter la quantité dacides gras mono-insaturés dans des plantes entières, des semences de plante et des matières végétales, par exemple des semences.
Patent CA-2999756-A1 (CA)
Inventor: HUANG LEAF
IPC: A61K48/00
Filed: 2016-09-15
Abstract: The subject matter described herein is directed to methods of modifying the micro-environment of a target cell or The methods comprise systemically administering to a subject a composition comprising a vector, wherein the vector comprises a construct for the expression of a trap in the target cell, wherein the trap is expressed in the target cell thereby modifiying the micro-environment. Also described herein are methods of reducing metastasis of a cancer comprising, systemically administering to a subject suffering from the cancer, a composition comprising a vector, wherein the vector comprises a construct for the expression of a trap, wherein the trap is delivered to and then expressed in tissue susceptible to metastasis, wherein metastasis of the cancer to the tissue is reduced. Compositions for carrying out the methods are also described.
Patent CA-3001617-A1 (CA)
Inventor: FISCHER DANIEL
IPC: A47J31/46
Filed: 2016-08-31
Abstract: The invention relates to a beverage preparation device (1) with a disk valve (6), comprising a valve housing (12) and a stack of disks (7) arranged therein, the disk valve having a preferably ceramic cover disk (8) comprising at least one fluid opening for fluid (5), especially water and/or steam, preferably embodied as a fluid inlet, and at least one control disk (10) arranged on a side of the cover disk (8) facing away from an outer front side of the cover disk (8), the control disk (10) being rotatable, manually and/or by means of a drive, about a rotational axis (R) in relation to the cover disk (8), between different operating positions. A pressure chamber (15) is formed outside the fluid opening (11), inside which a bearing pressure (P) can be exerted, by means of the fluid (5) flowing therethrough, along the rotational axis (R) on the outer front side (14) of the cover disk (9) in the direction of the control disk (10), and the pressure chamber (15) is delimited, in the radial direction in relation to the rotational axis (R), by an elastomer seal (13) preferably embodied as a peripherally closed ring seal, said seal being supported on the cover disk (8) in the axial direction. A cross-sectional surface of the pressure chamber, surrounded by the elastomer seal (13), and/or the pressure surface section (17) of the outer cover disk (8) adjacent to the fluid opening (11), which can be subjected to hydraulic pressure, corresponds to at least 20% of the axial projection surface of the cover disk (8) and/or the cross-sectional surface of the pressure chamber and/or the pressure surface section (17) of the outer cover disk (8) adjacent to the fluid opening (11), which can be subjected to hydraulic pressure, is larger than a cross-sectional surface of the fluid opening (11).
Patent CA-3003910-A1 (CA)
Title: Systeme et procede destines a evaluer un processus de nettoyage concernant une structure de conduit de transport de lait
Inventor: ENICKL JORGEN
IPC: A01J7/02
Filed: 2016-11-07
Abstract: La présente invention concerne le nettoyage d'une structure de conduit de transport de lait (110) consistant à introduire un fluide et une quantité de gaz (G) dans la structure de conduit de transport de lait (110). Ainsi, une augmentation de pression temporaire est produite, ce qui provoque la formation et l'acheminement d'une masse liquide (S) de fluide dans la structure de conduit de transport de lait (110). Un montage de capteur mesure au moins un paramètre lié à la masse liquide (S), et transfère de manière répétée des mises à jour dudit paramètre mesuré au processeur de données. Sur cette base, le processeur de données produit un indicateur (Ls) d'au moins une qualité du processus de nettoyage. L'indicateur représente un profil transversal de la masse liquide (S) dans au moins une position dans la structure de conduit de transport de lait (110).
Patent CA-3005052-A1 (CA)
Inventor: MARTIN ROY CHRISTIAN
IPC: A61B5/1455
Filed: 2016-11-11
Abstract: A method for monitoring glucose concentration in aqueous humor can include inserting an implantable device into an eye and determining glucose concentration as a function of glucose sensed at the implantable device. The method can optionally include optically detecting glucose concentration as a function of polarimetry and/or fluorescence. A system for monitoring glucose concentration can include devices described herein.
Patent CA-3005869-A1 (CA)
Inventor: MAHAR STEPHEN NELSON
IPC: H04W8/22
Filed: 2016-11-17
Abstract: A method, device and system for limiting mobile device functionality in a vehicle. When a vehicle is in motion, a motion detector initiates a signal generator, which transmits a disabling signal that is received and processed by software residing on a mobile device. Upon receipt and validation of the disabling signal, the software will alter the mobile device's system configuration to, for example, remove the ability of the mobile device to respond to typing and other touch screen functions and to send and/or receive text and/or e-mail messages for as long as the disabling signal is transmitted. Once the motion detector detects that the vehicle is no longer in motion, the signal generator ceases transmission of the disabling signal. After a predetermined time of not receiving a disabling signal, the software restores the mobile device's system configuration to its original configuration.
Patent CA-3006027-A1 (CA)
Title: Thin-film flowcells
Inventor: Perroud Thomas Daniel
IPC: C12Q1/68
Filed: 2016-12-27
Abstract: A sequencing instrument including a sequencing stage and a microscope. The sequencing stage has a reference plate with a flat reference surface. The microscope optical axis is perpendicular to the reference surface. The sequencing stage is configured to receive a flexible film having a plurality of DNA templates immobilized on a first side of the film, and to hold the flexible film against the flat reference surface with at least some of the plurality of DNA templates in an object plane that is perpendicular to the microscope's optical axis.
Patent CA-3007497-A1 (CA)
Title: Gypsum product composition, gypsum products, and a method for using a compound in gypsum board
Inventor: IRONSIDE KANE
IPC: C04B11/00
Filed: 2015-12-18
Abstract: A gypsum board composition was disclosed which comprises stucco, adhesive, water and additive for improving bonding, wherein the additive for improving bonding is shown in chemical formula as M ?M ?(OH) 2(A n-)·mH 2O,wherein M ? is a divalent metal ion, M ? is a trivalent metal ion, and A n- is an interlayer anion, and wherein M ?and M ? are different metals. Also, a gypsum board made with the composition of the above and a method for using a compound shown in the aforesaid chemical formula were disclosed.
Patent CA-3009019-A1 (CA)
Inventor: GANSLER MICHAEL THOMAS
IPC: F02C6/14
Filed: 2018-06-21
Abstract: A hybrid-electric propulsion system includes a propulsor, a turbomachine, and an electrical system, the electrical system including an electric machine coupled to the turbomachine. A method for operating the propulsion system includes operating, by one or more computing devices, the turbomachine such that the turbomachine rotates the propulsor; receiving, by the one or more computing devices, a command to accelerate the turbomachine while operating the turbomachine; and providing, by the one or more computing devices, electrical power to the electric machine to add power to the turbomachine, the propulsor, or both in response to the received command to accelerate the turbomachine.
Patent CA-3009956-A1 (CA)
Inventor: KOBAL GERD
IPC: A24F40/42
Filed: 2017-03-03
Abstract: A flavor assembly (14) for an e-vaping device cartridge (70) encloses a porous structure (202) that enables elution of flavorants from the structure (202) to form a flavored vapor. The structure (202) may include a three-dimensional network of material. The flavorant may be infused in the material. The material may include a botanical material. The material may draw the flavorant from a reservoir (23). The flavor assembly (14) may direct a raw vapor formed by a vaporizer assembly (22) to pass through the porous structure (202), so that the flavorant is eluted from the structure (202) into the vapor to form the flavored vapor. The flavor assembly (14) may be removably coupled with a vaporizer assembly (22). The flavor assembly (14) may be removably received into a flavor assembly compartment (413). The flavor assembly compartment (413) may be removably coupled to a vaporizer assembly (22). Flavor assemblies (14) may be swapped from the e-vaping device (10) to enable swapping of flavors provided to adult vapers during vaping.
Patent CA-3010010-A1 (CA)
Inventor: AUERBACH SHMUEL
IPC: A61B34/20
Filed: 2018-06-28
Abstract: Embodiments include methods, systems, and apparatuses for generating an enhanced electrocardiograph (ECG) that includes indicators of values of different types of supplemental information embedded into a trace of measured electrical potentials. More specifically, embodiments may include collecting first data samples of electrical potentials produced by a heart at a sequence of sampling times, and processing the data to calculate supplemental information over a number of sampling times. Based on the first data samples and the supplemental information, a trace of the electrical potentials collected at the sampling times is presented. The trace may have one or more embedded indicators of the supplemental information that vary responsively to the first data samples collected at each of the sampling times.
Patent CA-3010643-A1 (CA)
Title: Mecanisme de rochet a double cliquet et methode d'inversion
Inventor: ROSS DAVID T
IPC: B25B13/46
Filed: 2018-07-06
Abstract: Une clé à double cliquet est décrite, laquelle comprend un porte-cliquet pour sélectivement embrayer un encliquetage en une première et une deuxième direction dentraînement. Le porte-cliquet est raccordé fonctionnellement à au moins un cliquet. Le porte-cliquet comprend au moins une cavité qui loge au moins partiellement le cliquet. Le cliquet peut tourner autour de sa partie centrale dans la cavité lorsque le porte-cliquet est utilisé entre la première et la deuxième direction dentraînement.
Patent CA-3011544-A1 (CA)
Title: Product slicer
Inventor: MCGUFFIN-NOLL DOUGLAS
IPC: B26D1/01
Filed: 2017-01-31
Abstract: A product slicer having an adjustable gauge plate precisely positioned by the unique cooperation of a cam plate and a cam follower.
Patent CA-3013080-A1 (CA)
Title: Nrf2 activating compounds and uses thereof
Inventor: DUNCTON MATTHEW
IPC: C07D257/04
Filed: 2017-02-02
Abstract: Aspects of the present disclosure include compounds that activate Nrf2. Such compounds find use in the treatment of autoimmune and inflammatory diseases and disorders, such as for example psoriasis and multiple sclerosis. Embodiments of the present disclosure also relate to pharmaceutical compositions that include these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
Patent CA-3014053-A1 (CA)
Title: Thrust reverser actuating
Inventor: KOPECEK JOSEPH THOMAS
IPC: F02K1/76
Filed: 2017-02-08
Abstract: A thrust reverser includes: a thrust-reversing element movable between a stowed position and a deployed position; at least one hydraulic actuator operably coupled to move the thrust-reversing element between the stowed and deployed positions; at least one hydraulic primary lock configured to transition, in response to a first activation pressure, between an engaged state, where movement of the thrust-reversing element is inhibited, and a released state, where movement of the thrust-reversing element is uninhibited; and a directional control unit fluidly coupled to the hydraulic actuator and the hydraulic primary lock, the directional control unit configured to transition from a first stage to a second stage in response to a second activation pressure that is greater than the first activation pressure, and where a transition from the first stage to the second stage by the directional control unit causes the hydraulic actuator to move the thrust-reversing element to the deployed position.
Patent CA-3019214-A1 (CA)
Title: Method and compositions for hydraulic fracturing and for tracing formation water
Inventor: RULE JEFFREY DAVID
IPC: E21B47/10
Filed: 2017-04-18
Abstract: A method of hydraulic fracturing, and tracer composites for use in the fracturing procedure, for tracing the production of formation water from, one or more fractured zones. The tracer composites preferably include a formation water tracer material adsorbed onto a solid carrier material.
Patent CA-3022130-A1 (CA)
Title: Method of manufacturing wall elements for buildings
Inventor: BINDER MATTHEO JOHANNES
IPC: E04B1/348
Filed: 2018-10-25
Abstract: A method of manufacturing wall elements for buildings, wherein cross laminated timber panels of a specific width and length are stocked in a store, and wherein the panels are sawed up transversely to the longitudinal direction to obtain cross laminated timber panels of the same width and smaller length, wherein a plurality of panels are placed onto a conveying track transversely to the direction of running, and indeed such that the panels are flush at the top and bottom and the side edges of consecutive panels contact one another; in that the panels on the conveying track are connected along the contacting longitudinal sides to form a cross laminated timber apron; and in that the apron is sawed up transversely to the direction of running of the conveying track to obtain cross laminated timber boards of a defined width.
Patent CA-3022557-A1 (CA)
Title: Optical fiber and device for releasing molecules
Inventor: ALIBERTI ANNA
IPC: A61M37/00
Filed: 2017-05-02
Abstract: The present invention relates to an optical fiber and a device including the optical fiber. The optical fiber is an optical fiber (1) functionalized with at least one particle (1) of a polymeric gel comprising at least one photosensitive molecule (7) and at least one biomolecule (6), wherein the at least one particle (2) of the polymeric gel is covalently bound to said optical fiber (1).
Patent CA-3025588-A1 (CA)
Inventor: GOFMAN IGOR Y
IPC: G06F1/26
Filed: 2017-06-01
Abstract: Embodiments of the present invention provide systems, apparatus, and methods for powering electronic devices with low voltage batteries. Embodiments include a circuit including a transistor having a base, an emitter, and a collector; a microcontroller having an output port, a system power terminal, and an input port; a first signal generated from the output port of the microcontroller and coupled to an enable pin of a DC-DC booster; and a second signal generated from the output port of the microcontroller and coupled to the base of the transistor, wherein the second signal is an inverted version of the first signal. The emitter of the transistor is coupled to ground and the collector of the transistor is coupled to the enable pin of the DC-DC booster. Numerous additional aspects are disclosed.
Patent CA-3030416-A1 (CA)
Title: Polyamine phosphorus dendrimer materials for carbon dioxide capture
Inventor: THOMPSON SAMUEL JOHN
IPC: C08J7/043
Filed: 2019-01-17
Abstract: The present disclosure provides novel solid sorbents synthesized by the reaction of polyamines with polyaldehyde phosphorous dendrimer (P-dendrimer) compounds.  The sorbents are highly stable and exhibit rapid reaction kinetics with carbon dioxide, making the sorbents applicable for carbon capture, and can be easily regenerated for further use. The material is stable to aqueous and organic media, as well as strong acid and bases. The sorbent maintains full capacity over extended use. The material can be used for CO2 capture from pure CO2 streams, mixed gas streams, simulated flue gas, and ambient air. Additionally, the material can be adhered to surfaces for reversible CO2 capture applications outside of bulk particle-based processes.
Patent CA-3030483-A1 (CA)
Inventor: LUTTRULL JEFFREY K
IPC: A61N7/02
Filed: 2017-07-28
Abstract: A process that provides protective therapy for biological tissues or fluids includes applying a pulsed energy source to a target tissue or a target fluid having a chronic progressive disease or a risk of having a chronic progressive disease to therapeutically or prophylactically treat the target tissue or target fluid. The pulsed energy source has energy parameters selected so as to raise the target tissue or bodily target fluid temperature up to a predetermined temperature for a short period of time to achieve a therapeutic or prophylactic effect, while the average temperature rise of the target tissue or target fluid over a longer period of time is maintained at or below a predetermined level so as not to permanently damage the target tissue or target fluid.
Patent CA-3031231-A1 (CA)
Inventor: BLAUWKAMP TIMOTHY A
IPC: C12N15/10
Filed: 2017-08-07
Abstract: This disclosure provides methods that are useful for reducing or inactivating contaminant nucleic acids.
Patent CA-3031589-A1 (CA)
Inventor: LIN CHINYU
IPC: A61K39/02
Filed: 2017-09-22
Abstract: Uses of IL-13 antagonists for treating atopic dermatitis are provided. Also provided are methods of treating atopic dermatitis and methods of reducing the severity of atopic dermatitis by administering IL-13 antagonists.
Patent CA-3033883-A1 (CA)
Inventor: ZHAO YONG
IPC: C12M3/00
Filed: 2017-08-29
Abstract: The described invention provides a pharmaceutical composition comprising a therapeutic amount of an educated mononuclear cell product, a process for preparing the educated mononuclear cell product, and a method for treating a disease characterized by lymphocyte autoreactivity. Mononuclear cells from a diseased subject are co-cultured with a viable population of adherent umbilical cord blood stem cells at at least 80% confluence to form an educated mononuclear cell product. A therapeutic amount of the educated mononuclear cell product is returned by infusion intravascularly to the subject. The therapeutic amount is effective to modulate autoreactivity in a T cell compartment of the subject and to reduce symptoms of the disease characterized by lymphocyte autoreactivity.