baber/WOPTO huggingface dataset:
Patent PT-897904-E (PT)
Inventor: CURTZE JURGEN
IPC: C07C45/67
Filed: 1998-08-18
Abstract: Substituted benzophenone compounds are disclosed, having the formula:   <CHEM> The compounds are useful as fungicides having high systemicities.
Patent PT-975334-E (PT)
Inventor: SHAH SUBODH
IPC: A61K47/48
Filed: 1998-04-17
Abstract: The present invention relates to improved methods of making polymeric microparticles containing a variety of active ingredients, e.g. protein drugs. In addition, the present invention relates to using the above active protein containing polymeric microparticles to prepare compositions for the sustained delivery of the therapeutics.
Patent IE-860056-L (IE)
Title: Damped spring
IPC: F16F3/093
Filed: 1986-01-09
Abstract: A combined spring and damper comprises a plurality of spring elements (1), each of zig-zag form, disposed in radial planes with respect to a common axis. Also situated on the axis is a mass (7) of resilient material. When the spring is compressed along the axis the inward contraction of inner reflex portions (3) of the spring elements is resisted by the mass of resilient material, and the resulting axial movement of the radially inner reflex portions is resisted by contact with the mass of resilient material and axial compression thereof.
Patent IE-890107-L (IE)
Title: Synergic antioxidant mixture
IPC: A23D7/06
Filed: 1989-01-16
Abstract: To protect a fat which is sensitive to oxidation, or a foodstuff or cosmetic product containing a fat which is sensitive to oxidation, a mixture of tocopherol, ascorbic acid and lecithin is used. Such a mixture is especially effective for protecting oils which are rich in polyunsaturated fatty acids.
[EP0326829A2]
Patent IE-860233-L (IE)
Title: Detergent composition¹¹compositions
IPC: C11D3/32
Filed: 1986-01-28
Abstract: A particulate fabric softening and antistatic built detergent composition includes synthetic organic detergent, builder for the detergent, bentonite and higher aliphatic isostearamide antistat. The bentonite and antistat are often preferably agglomerated together and may be admixed with spray dried detergent "base beads" which are preferably of similar particle sizes and which include anionic synthetic organic detergent and builder, to make the fabric softening and antistatic detergent composition. Also within the invention is a process for washing and drying laundry which produces laundry that is soft and static-free or of low electrostatic charge despite having been subjected to a tumble drying process which normally makes laundry of similar fabrics electrostatically charged and subject to objectionable "static cling".
[US4626364A]
Patent IE-820239-L (IE)
Title: Carbapenem derivatives
IPC: A61P31/04
Filed: 1982-02-03
Abstract: A process for the preparation of an antibacterially active compound of the formula (I): <CHEM> and salts and esters thereof wherein R<1> and R<2> independently represent hydrogen or an organic group, and R<3> is an optionally substituted aromatic or heteroaromatic moiety, which comprises reacting a compound of the formula (II): <CHEM> wherein R<a> is hydrogen or a carboxy-blocking group, with X-R<3> wherein X is a displaceable group, In addition certain compounds within the formula (II) are novel.
[EP0061231A1]
Patent IE-20236-L (IE)
Title: Resilient torsion joints
IPC: H04B15/02
Filed: 1952-09-23
Abstract: 710,244. Resilient joints. NEIDHART, H. J. Sept. 22, 1952 [Oct. 23, 1951], No. 23697/52. Class 108(3) The inner member D of the elastic joint forming the subject of Specification 652,266 is formed with flanges F. These prevent over-rotation of the inner member D and permit the latter to be smaller, and the elastic masses M to be larger, than in the prior construction. A radius at S may be replaced by a sharp corner. The flange F may extend as far as a circle inscribed within the outer member A. The flanges F may extend further than this, and they then provide a positive stop.
[GB710244A]
Patent IE-40864-L (IE)
Title: Antibiotic
IPC: A61K35/74
Filed: 1975-03-19
Abstract: A process for the preparation of an antibacterially active carboxylic acid compound designated as MM 13902 and salts thereof, which substance MM 13902 is sold carbxylic acid characterised in that its pure di-sodium salt; (i) is highly soluble in water, soluble in methanol and substantially insolubel in chloroform, diethylether and hydro-carbons; (ii) in aqueous solution has an ultra-violet spectrum substnatially as shown in Fig. 1 of the accompanying drawings with absorption maxima at about 305 and 225 mm; (iii) when present at 0.4% w/w in a freshly prepared KBr disc has an infra-red absorption spectrum substantially as shown in Fig. 2, of the accompanying drawings with absorption maxima at inter alia about 3450, 2950, 1750, 1620, 1510, 1400 and 1260cm1; (iv) has an n.m.r. specturm substantially as shown in Fig. 3 of the accompanying drawings when taken in a freshly prepared solution in D2O with inter alia (a) a pair of low fiedl doubelts centred at approximately 2.85GAMMA and 4.00GAMMA with coupling constants of approxiamtely 14 Hz; (b) a doublet centered at approxiamtely 8.55 and (c0 a sharp signlet at approxiamtely 8.00; (v) has the following approxdiamte Rf values ethn run on a cellulose thiin layer chromatogrpahy system; (a) n_butanol/ isopropanol/ water-7:7:6 v/v; Rf=0.72 (b) isopropanol/water-7:3 v/v; Rf=0.85 (c) n-butanol/ethanol/water-7:7:6 v/v; Rf0.81 (d) n-propanol/water-4:1; Rf=0.75; (vi) has an I50 of between 0.001/ug/ml and 0.0001/ug/ml against the beta-lactamase of Escherichia coli B11; (vii) synergises the activity of ampicillin against organisms includign strains of Escherichia coli, Klebnsiella aerogenes, Proteus mirabills, Proteus morganii and Staphylococcus aureus Russell; which process comprises the aerobic grouth of a MM 13902 producing strain of Streptomyces in the presence of assimilable soruces of cabron, nitrogen, sulphur and mineral salts in a solid or semi-solid nutritive medium or in a liquid medium in which the nutrients are dissovled or supsended, at a temperature of 28+/-2degree C for 2 to 3 days and thereafter extracting the antibiotics opresent from the culture medium, either by initial absorption on to and then elution from active characoal or an ion-exchange resin cotnaining tertiary amino grous or quternary ammonium groups or by extracting into a solution of a lipophilic ammonium salt in a water immiscible soluvent at a temperature not exceeding 20degrees C and separatign the MM 13902 therefrom by column chromatograpohy either by using a cellulose or silica-gel column and eluting eith mixtures of water with water-miscible organic solvents or by using columns of ion-exchange resins containing tertiary amino grouups or quarternary ammonium groups and eluting with aqueous solutions of electrolytes buffered to appropriate neutrality. [IN141262A1]
Patent IE-38750-L (IE)
Title: 7 -(d - alpha - amino -1,4 - cyclohexadien - 1 -¹ylacetamido) desacetoxycephalosporanic acid dihydrate
IPC: A61K31/545
Filed: 1973-05-01
Abstract: 1426266 Cephradine dihydrate E R SQUIBB & SONS Inc 4 May 1973 [1 June 1972] 21368/73 Heading C2C The novel compound cephradine dihydrate (being the dihydrate of the known cephalosporin compound cephradine, which is 7-(D-α- amino - 1,4 - cyclohexadien - 1 - ylacetamido) desacetoxycephalosporanic acid) is prepared by neutralizing an acid addition salt of base salt of cephradine in aqueous solution or suspension at a temperature of 0 to 25 C. By the word "neutralizing" is meant bringing to the point at which the acid or base moiety of the acid addition or base salt is exactly neutralized by the added base or acid respectively, this point being about pH 5À5 rather than the conventional pH 7 of a strong acid/strong base interaction. The dihydrate, which is isolated by crystallization (preferably after seeding), has a characteristic X-ray diffraction pattern (using a copper K-α radiation source), and differs from known cephradine in its crystalline form, water-solubility and behaviour on vacuum drying at elevated temperature which converts the dihydrate irreversibly into the conventional form of cephradine. The novel cephradine dihydrate may be made up into antibiotically active pharmaceutical compositions with a pharmaceutically acceptable diluent or carrier.
[GB1426266A]
Patent FI-822692-L (FI)
Inventor: DOHERTY JAMES B
IPC: C07D405/06
Filed: 1982-08-02
Abstract: Pyrrole compounds of the structural formula: <CHEM> or a pharmaceutically acceptable salt, ester or amide thereof have been prepared via hydrolysis of a precursor-ester after high temperature decarboxylation of from direct acidic decarboxylation of a precursor diacid. In the above formula, Ar is phenyl, substituted phenyl, pyridyl, pyrryl, substituted pyrryl, furyl or thienyl; R is, e.g., hydrogen, loweralkyl, lowercycloalkyl, lower(cycloalkyl-alkyl), loweralkenyl or halo-loweralkyl; R<1> is hydrogen or loweralkyl; R<2> is hydrogen, loweralkyl or halo; R<3> is, e.g., hydroxy, loweralkoxy, substituted loweralkoxy, amino, substituted amino, morpholinyl, glucosamino or heterocyclyl-oxy; X is (CH2)0-10-, -COCH2- or -CH2CO-; and Y is oxygen, sulfur, sulfinyl, sulfonyl, CH2 or H with the proviso that when Y is CH2-, Ar can only be pyrryl, and when Y is H, Ar is pyrryl and R is not present. The compounds are analgesic and anti-inflammatory agents of high activities out low ulcerogenic side effects.
Patent FI-853690-L (FI)
Inventor: BUCHARDT OLE
IPC: A61K31/34
Filed: 1985-09-25
Abstract: A process for obtaining purified podophyllotoxin from an impure podophyllotoxin containing starting material comprising forming a solution of the starting material, forming a solid complex of podophyllotoxin and an aromatic or heteroaromatic compound other than benzene, and separating the solid complex from the solution.
Patent IE-41071-L (IE)
Title: Herbicidal composition
IPC: C07D231/12
Filed: 1975-05-26
Abstract: 1466634 Plant growth regulator AMERICAN CYANAMID CO 28 April 1975 [28 May 1974] 17633/75 Heading C1B [Also in Division A5] A synergistic herbicidal and plant growth regulating composition comprises a mixture of (a) a 1,2-dialkyl-3,5-diphenyl-IH pyrazolium salt of the formula wherein R 1 is methyl; R 2 is alkyl C 1 -C 4 ; X is an anion; Y, Y<SP>1</SP>, Z and Z<SP>1</SP> are each hydrogen, halogen, methyl or methoxy; and m is an integer from 1-3; provided that only one phenyl ring can be substituted on the carbon parato the pyrazolium ring with a substituent other than hydrogen; and (b) a compound of the formula: R-N(CH 3 ) 3 Y where R is a lower aliphatic radical (C 1 -C 4 ) selected from haloalkyl, alkylene, haloalkylene, cyanoalkyl, mercaptoalkyl, alkoxyalkyl and epithioalkyl; and Y is non-phytotoxic anion, the cation of I and II compounds being present in a weight ratio of from 1 : 1 to 1 : 16 respectively. Suitable anions for compounds I and II include chloride, bromide, iodide, acetate, citrate, succinate, formate, sulphate, hydroxide, bisulphate, methyl sulphate, benzene sulphonate, C 1 -C 3 alkoxy benzene sulphonate and C 1 -C 3 alkyl benzene sulphonate. A particularly preferred composition comprises (a) 1,2-dimethyl-3,5-diphenyl-IH- pyrazolium chloride, bromide, methyl sulphate or bisulphate and (b) (2-chloroethyl)-trimethylammonium chloride, bromide, fluoride or iodide. Surfactants, spreaders and stickers may also be added. The composition can also be used for the concurrent control of relative stem growth of crops, e.g. wheat, barley and rye.
[GB1466634A]
Patent IE-851325-L (IE)
Title: Panel rigidising system
IPC: E04B2/74
Filed: 1985-05-29
Abstract: Panel connection rigidizer 32 for space dividing wall panel systems of the type employing cylindrical support posts 12 to interconnect and support the wall panels (10, Fig. 1). The panel rigidizer includes a hub portion 34 and laterally extending leg portions 36. The hub portion 34 is adapted to overlie the support post and be secured thereto while the leg portions include spaced parallel ribs 42 on the under side which are received in spaced parallel grooves 22 in the upper edge of the wall panels. A cover member 46 may be releasably secured to the leg portions of the panel rigidizer. <IMAGE>
[GB2159852A]
Patent IE-871480-L (IE)
Title: Controlled release pharmaceutical compositions.
IPC: A61K9/26
Filed: 1987-06-04
Abstract: A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a controlled release matrix comprising a water soluble polydextrose. The controlled release matrix may also contain at least one of a digestible C8-C50 substituted or unsubstituted hydrocarbon, especially a C12-C36 fatty alcohol, and a polyalkylene glycol, especially polyethylene glycol. Optionally, the matrix may contain a cellulose ether, especially a hydroxyalkylcellulose or a carboxyalkylcellulose.
Patent IE-801592-L (IE)
Title: Dry etching of metal film.
IPC: C23F4/00
Filed: 1980-07-30
Abstract: A process for dry etching an aluminum film or an aluminum based film in the production of a semiconductor device, wherein a mixed gas of carbon chloride and boron chloride is used as the etchant gas.
[US4350563A]
Patent IE-41426-L (IE)
Title: Stabilized polyalkylene glycols
IPC: C07D457/02
Filed: 1975-07-17
Abstract: 8?-ERGOLINE I COMPOUNDS This invention provides new compounds of formula I, I wherein X is hydrogen, chlorine or bromine, R1 is methyl or ethyl, and R2 is CH2-CN, or a group NR3R4, wherein R3 is hydrogen or alkyl of 1 to 4 carbon atoms, and R4 is formyl, alkanoyl of 2 to 5 carbon atoms in the aggregate thereof, alkoxycarbonyl of 2 to 5 carbon atoms in the aggregate thereof, mono- to trihalogenalkoxycarbonyl of 3 to 5 carbon atoms in the aggregate thereof, the alkoxy radical of which is substituted by halogen in a position other than .alpha. to the oxygen, or the radical SO2R5, wherein R5 is alkyl of 1 to 4 carbon atoms, monoto tri-halogenalkyl of 1 to 4 carbon atoms, phenyl, pyridyl, phenyl monosubstituted by halogen or alkoxy of 1 to 4 carbon atoms, or a group NR6R7, wherein each of R6 and R7 is independently hydrogen or alkyl of 1 to 4 carbon atoms, or R6 and R7 together are one of the groups (CH2)n or (CH2)2-A-(CH2)2, wherein n is a number from 3 to 7, and A is oxygen, sulphur or nitrogen substituted by alkyl of 1 to 4 carbon atoms or phenyl, useful as prolactin secretion agents and antiparkinson agents.
[CA1073452A]
Patent IE-43417-L (IE)
Title: Process for preparing iminodiacetonitrile
IPC: C07C255/24
Filed: 1976-08-19
Abstract: PROCESS FOR PREPARING IMINODIACETONITRILE Iminodiacetonitrile is prepared by a process comprising: (a) forming an aqueous reaction mixture by admixing water, hexamethylenetetramine, formaldehyde, and HCN; and (b) forming iminodiacetonitrile by passing the aqueous reaction mixture through a continuous reaction zone while maintaining the temperature within the continuous reaction zone at 50-250.degree.C. The resulting iminodiacetonitrile can be recovered or it can be hydrolyzed to form an alkali metal salt of iminodiacetic acid which can be recovered or converted to iminodiacetic acid which can be recovered. In other embodiments: (a) the hexamethylenetetramine solution and the formaldehyde solution can be combined before being admixed with the HCN; or (b) the formaldehyde solution and the HCN can be admixed with a stabilizing acid to form an acid stabilized aqueous solution of formaldehyde and HCN before being admixed with the hexamethylenetetramine solution in the reaction zone in which iminodiacetonitrile is formed.
[CA1061800A]
Patent IE-881907-L (IE)
Title: Liquid compositions polymerizable to yield organic gases
IPC: C08F218/00
Filed: 1988-06-23
Abstract: A liquid composition polymizable by the free-radical polymerization route, with a low shrinkage, to yield organic glasses endowed with high thermal stability, is constituted by the product of transesterification of diallyl-carbonate (A) with a mixture of diol (B) and of a polyol (C) containing from 3 to 6 hydroxy groups in the molecule, or a mixture of a diol (B) with a cycloaliphatic diol (C min ), by operating with a molar ratio of A/(B+C) or A/(B+C min ) equal to, or larger than, 3/1, and with an amount of (C) in the (B+C) mixture equal to, or smaller than, 70% by weight, or with an amount of (C min ) in the (B +C min ) mixture equal to, or smaller than, 90% by weight.
[EP0302537A1]
Patent IE-862315-L (IE)
Title: Seismic receiver for use in a well borehole
IPC: G01V1/40
Filed: 1986-08-29
Abstract: A seismic receiver (R) is provided for measuring seismic signals transmitted through the earth and received in a well borehole (10). A reversible electrical motor (M) drives a harmonic driver reducer (80) which amplifies the torque provided to drive a ball screw (92). The ball screw moves linearly along the axis of the well borehole to control the extension of a damp arm (C) into and out of an extended position in contact with subsurface earth adjacent the well borehole. A releasable electric dutch (66) is provided so the receiver is retrievable in the event of a power failure while the clamp arm is extended.
Patent IE-872471-L (IE)
Title: Method for producing self-supporting ceramic bodies with¹refined microstructures
IPC: C04B35/65
Filed: 1987-09-14
Abstract: A ceramic body is formed of alumina obtd. by oxidn. of molten aluminium with an oxygen-contg. gas under such conditions that the product remains in contact with the metal to form a body through which metal is continuously drawn to the oxidant interface to cause growth of the body. The body may also include non-oxidised metal components. - The body is caused to have a refined microstructure by including a process modifier either in the molten metal or in contact with it. - In a modification a body of filler is located adjacent to the metal bath so that it becomes embedded in the oxidn. product. Pref. the modifier is Cu, Ni, Fe, Zr, Cr, Ti, W, Nb or Co. - The modifier is pref. used in an amt. of 0.1-10 wt.% based on the aluminium metal. It may be alloyed with the latter, applied as a powder to the growth surface of the initial aluminium body, or mixed with the filler, which may be silicon carbide. (Dwg.0/3)
Patent IE-822847-L (IE)
Title: Pesticidal suspension concentrate
IPC: A01N25/04
Filed: 1982-11-30
Abstract: 1. Suspension concentrates of plant protection agents based on a pesticide insoluble or sparingly soluble in water or a physiologically acceptable solvent, a phospholipid and an organic solvent or solvent mixture, characterised in that the concentrate consists of a) 15-35% of a pesticide insoluble or sparingly soluble in water or a physiologically acceptable solvent at 2% or less and having a melting point of > 40 degrees C, b) 15-35% of a phospholipid from the group phosphatidylcholine, the hydrogenated phosphatidylcholines, phosphatidylethanolamine, the N-acylphosphatidylethanolamines, phosphatidylinositol, phosphatidylserine, and the mixtures of several of said phospholipides and c) 40-60% of a solvent or solvent mixture from the group of the alcohols and the ethers, the mean particle size being =< 1 mu m.
Patent IE-883297-L (IE)
Title: Disinfecting solid refuse with active chlorine
IPC: A61L11/00
Filed: 1988-11-01
Abstract: A method for disinfecting solid refuse contained in bags by the action of chlorine released from solid mixtures containing halazone, implemented by the following stages:   a) bringing the solid mixture containing halazone into contact with an alkaline solution in a suitable reaction container;   b) immediately introducing said container into the bag; c) closing the bag to allow the chlorine released in the gaseous state by the reaction to exercise its disinfectant action.   The invention also relates to said reaction container, which has the characteristic of confining the aqueous suspension in such a manner as to prevent it escaping whatever its position.
Patent IE-873340-L (IE)
Title: Pharmaceutically active compounds.
IPC: C07D307/20
Filed: 1987-12-09
Abstract: The disclosed invention is compounds represented by the formula <CHEM> and pharmaceutically acceptable acid addition, basic addition and quarternary amine salts thereof and pharmaceutically acceptable solvates thereof, wherein each Z is independently tetiary butyl, phenyl, naphthyl or adamantyl; substituted phenyl, wherein the substituents are one or more of halogen, lower alkoxy, phenoxy, nitrile, nitro, phenyslsulfonyl, loweralkylsulfonyl, oxazol-2-yl, lower alkanoyl, benzoyl, lower alkoxycarbonyl, lower alkyl, lower alkylthio, phenyl, phenylaminothiocarbonyl, or lower alkylaminothiocarbonyl; 4 or 6 membered unsubstituted or substituted heterocyclic ring containing at least one nitrogen with the remaining members of the ring being at least one carbon, and optionally sulfur or oxygen, wherein the substituents are one or more of carboxyl, hydroxymethyl, lower alkyl, loweralkylcarbonyl or aryl lower alkyl; X and Y are each independently a bond, -O-, <CHEM> each Q is independently a divalent substituted or unsubstituted, straigh or branched chain lower alkanediyl, lower alkanediyl-cycloalkaneidyl-lower alkanediyl, lower alkenediyl, lower alkynediyl, phenylene, dihydrofurandiyl, tetrahydrofurandiyl, tetrahydropyrandiyl, or, loweralkanediyl-tetrahydrofurandiyl-loweralkanediyl, wherein the substituents are one or more of hydroxy, epoxy, fluorine, chlorine, azide, or amino; W is a monovalent substituted or unsubstituted aryl group or a heterocyclic single or fused ring containing from 4 to 10 ring atoms, at least one hetero atom of which is a nitrogen atom and the remaining ring atoms being at least one carbon and optionally sulfur or oxygen, wherein the substituents are one or more of hydroxy, oxo amino, carbamoyl, carboxyl, nitrile, nitro, lower alkoxy carbonyl, halogen, sulfamyl, lower alkyl, lower alkylthio, lower alkoxy, hydroxyloweralkyl, lower alkoxycarbonylloweralkyl, amino loweralkyl, carboxyloweralkyl, guanidino, thioureido, lower alkylsulfonylamino, aminocarbonylloweralkyl, allyloxycarbonylmethyl or carbamoyloxyloweralkyl; with the proviso that W cannot be substituted or unsubstituted isoxazolyl, and W' is divalent W. The compounds have antiviral activity, antiinflammatory activity and are PAF inhibitors.
[EP0274867A2]
Patent IE-930589-L (IE)
Title: Anti-lymphotoxin antibody, its production and use
IPC: C07K16/18
Filed: 1985-05-28
Abstract: Lymphotoxin (I) absolutely free from homologous proteins that are unidentified or present in unknown amounts is new. Unglycosylated (I) is new. Variant (I) in which an amino acid residue in the (I) sequence has been deleted or substd. by another residue, or in which another residue has been inserted, is new. Provided that (I) having a sequence with an amino terminal at Leu(+)1 or His(+)23 is excluded. Nucleic acid encoding (I) and selected from (a)-(c) is new. (a) DNA encoding (I) free from DNA encoding other proteins of the organism from which the DNA originated; (b) DNA encoding (I) free from untranslated intervening sequences; and (c) nucleic acid capable of hybridising to nucleic acid encoding (I), provided that the acid does not have the nucleotide sequence of natural DNA or RNA encoding (I).
Biologically active lymphotoxin polypeptides are synthesized in recombinant cell culture. Novel nucleic acid and vectors incorporating same are provided. The compositions and processes herein enable the economical preparation of compositions containing uniform lymphotoxin polypeptides and variant lymphotoxins having amino acid sequences that differ from those found in nature. The lymphotoxins are purified to a specific activity of 2-10 x 10<7> unitllmg of protein by purification using a novel immobilized, lymphotoxin-neutralizing monoclonal antibody. 
[EP0164965A2]
Patent NO-773361-L (NO)
Title: Fremgangsmaate ved fremstilling av corticoider
Inventor: ANNEN KLAUS
IPC: C07J5/00
Filed: 1977-10-03
Abstract: Fremgangsmåte ved fremstilling av corticoider