baber/WOPTO huggingface dataset:
Patent DE-69334006-D1 (DE)
Inventor: JOERGENSEN STEEN TROELS
IPC: C12N1/20
Filed: 1993-12-22
Granted: 2006-05-24
Abstract: A method of amplifying in vivo a DNA sequence B present in a genome of a parent cell, comprising (a) integrating in a genome of said cell a DNA construct comprising the structure C-M-A-D, in which both A and C denote a DNA sequence which is homologous with a genomic DNA fragment either flanking or overlapping the DNA sequence B to be amplified or being a subsequence of the DNA sequence B constituting one of the ends of said sequence B, the sequence C being located in the opposite end of the sequence B as compared to A, D denotes a DNA sequence which is homologous with a genomic DNA fragment located distal for C as compared to B, and M denotes a DNA sequence encoding a selection marker, (b) selecting for cells in wich the DNA sequence M has been integrated in the genome, which cells comprise, in any orientation, the structure A-B-C-M-A-D, and (c) propagating the cells selected in step (b) under increasing selection pressure to obtain a cell which has obtained an increased number of genomically integrated copies of the DNA sequences B and M.
Patent DE-69425237-D1 (DE)
Inventor: MORIYAMA JIRO
IPC: B41J2/14
Filed: 1994-12-27
Granted: 2000-08-17
Abstract: There is disclosed an ink-jet head for performing recording by discharging an ink, including a discharge port for discharging the ink, and an ink channel which communicates with the discharge port and is provided with a discharge energy generating element for discharging the ink. An optical element is arranged at a position, corresponding to the ink channel, of the ink-jet head. There are also disclosed an ink-jet apparatus using the ink-jet head and a substrate for the ink-jet head. <IMAGE>
Patent DE-69429082-D1 (DE)
Inventor: TAM CHERK SHING
IPC: C12N15/09
Filed: 1994-03-14
Granted: 2001-12-20
Abstract: A polypeptide substance isolated from rat serum which, upon administration to rats incapable of producing PTH (parathyroidectomized rats), produces an increase in the observed bone mineral apposition rate. The substance has been isolated in two forms, a first larger polypeptide having a molecular weight about twice that of a second smaller polypeptide. The first eleven amino acids of the sequence of the smaller polypeptide have been determined to be Gly Pro Gly Gly Ala Gly Glu Thr Lys Pro Ile. The first seven amino acids of the larger polypeptide have been determined to be Gly Pro Gly Gly Ala Gly Glu. The larger polypeptide might be the dimer of the smaller peptide. A nucleic acid probe, based on the amino acid sequence of the rat peptide was used to screen a human liver cDNA fetal library. A polypeptide was thus chemically synthesized according to the sequence Gly Ile Gly Lys Arg Thr Asn Glu His Thr Ala Asp Cys Lys Ile Lys Pro Asn Thr Leu His Lys Lys Ala Ala Glu Thr Leu Met Val Leu Asp Gln Asn Gln Pro. The bone apposition rate in rats increases in a dose dependent fashion upon administration of this chemically synthesized compound.
Patent DE-69431294-D1 (DE)
Inventor: DELEAN BRUNO
IPC: G06F3/048
Filed: 1994-03-25
Granted: 2002-10-10
Abstract: A method for image processing in a computerized system reduces the amount of memory required for image processing and produces a layered effect which permits complex manipulation such as scaling and rotation without long delay, while allowing earlier versions of the visual image to be recalled. The method involves pre-processing, image editing and raster image processing.
Patent DE-69501379-D1 (DE)
Inventor: CARUSO NANCY
IPC: H01J61/82
Filed: 1995-04-04
Granted: 1998-02-12
Abstract: A metal halide lamp includes a discharge vessel with a ceramic wall and a filling which comprises besides mercury and a halogen also Na, Tl and one or several of the elements from the group formed by Sc, Y and lanthanides. The filling also contains Mg to improve lumen maintenance.
Patent DE-69502496-D1 (DE)
Inventor: COUPART ERIC
IPC: H02K1/16
Filed: 1995-06-19
Granted: 1998-06-18
Abstract: PCT No. PCT/FR95/00810 Sec. 371 Date Mar. 7, 1996 Sec. 102(e) Date Mar. 7, 1996 PCT Filed Jun. 19, 1995 PCT Pub. No. WO95/35592 PCT Pub. Date Dec. 28, 1995Each stator lamination (2) is angularly offset with respect to the following adjacent lamination, about an axis (4) of the stator (1, 3), by a constant angle ( alpha ) equal to a multiple of the angle corresponding to the slot pitch, and has a square shape, each corner (5) being truncated to a circular outline (6). At least one of the two truncated corners (5) of each lamination (2) is linked to the corner (5) corresponding to each of the two adjacent laminations (2) by at least one welding point (11) located in a region where the two outlines (6) extend or are superimposed. The welding points (11) are located in predetermined respective angular positions cyclically reproducible in relation to the stator axis (4) and are uniformly distributed about the axis (4) so that the welding points (11) are aligned according to lines (15a, 15b) of welding points (11) substantially parallel to the stator axis (4).
Patent DE-69510427-D1 (DE)
Inventor: QIAN XUE-YU
IPC: H01L21/205
Filed: 1995-10-13
Granted: 1999-07-29
Abstract: The disclosure relates to a coil antenna (30) for radiating RF power supplied by an RF source (64) into a vacuum chamber (54) of an inductively coupled plasma reactor which processes a semiconductor wafer in the vacuum chamber. The reactor has a gas supply inlet (56) for supplying processing gases into the vacuum chamber. The coil antenna includes plural concentric spiral conductive windings (32, 34, 36), each of the windings having an interior end (32a, 34a, 36a) near an apex of a spiral of the winding and an outer end (32b, 34b, 36b) at a periphery of the spiral of the winding, and a common terminal (38) connected to the interior ends of the plural concentric spiral windings. The RF power source is connected across the terminal and the outer end of each one of the windings. <IMAGE>   <IMAGE>
Patent DE-69523356-D1 (DE)
Inventor: DUBOIS JEAN-LUC
IPC: A61K8/00
Filed: 1995-02-15
Granted: 2001-11-29
Abstract: Cosmetic or pharmaceutical compsn. contains liposomes including at least one compound of formula (I). R1 = CN, NO2, or halogen; R2 = CF3 or halogen; -A-B- = -C(=X)-N(R3)- or -C(SR3)=N-; X = O or S; R3 = alkyl, alkenyl, alkynyl, aryl, or aralkyl (all with ≤ 12C, opt. substd. by one or more gps. R) tri(1-6C)alkylsilyl, ≤ 7C acyl, ≤ 7C acyloxy or H; R = OH, halogen, SH, CN, ≤ 7C acyl, acyloxy ≤ 7C, aryl, O-aryl, O-aralkyl, S-aryl, the S atom may be oxidised, carboxy (or its ester, amide or salt), monoalkylamino, dialkylamino, 3-6 membered heterocycle contg. one or more O, S or N; Y = O, S, or NH. In R and R3, alkyl (except for trialkylsilyl), alkenyl and alkynyl are opt. interrupted by O, N or (oxidised) S; and aryl and aralkyl have ≤ 12C and are opt. substd. by halogen, alkyl, alkenyl, alkynyl, alkoxy, alkenyloxy, alkynyloxy, or CF3.
Patent DE-69523643-D1 (DE)
Inventor: MOLLER HENRIK
IPC: H04S1/00
Filed: 1995-02-27
Granted: 2001-12-06
Abstract: The invention relates to improved methods and apparatus for simulating the transmission of sound from sound sources to the ear canals of a listener, said sound sources being positioned arbitrarily in three dimensions in relation to the listener. In particular, the invention relates to new and improved methods for measurement of Head-related Transfer Functions, new and improved Head-related Transfer Functions, new and improved methods for processing Head-related Transfer Functions, and new methods of changing, or of maintaining, the directions of the sound sources as perceived by a listener. The measurement method have been improved so that it is now possible to measure and/or construct Head-related Transfer Functions for which the time domain descriptions are surprisingly short and for which the differences from one individual to the other are surprisingly low.The new Head-related Transfer Functions can be exploited in any application concerning simulation of sound transmission, e.g. auralization of concert halls, measurement, simulation, or reproduction of sound, such as in binaural synthesis, e.g. for generation, by means of two sound sources, such as by headphones or by two loudspeakers, the perception of a listener that he is listening to sound generated by a multichannel sound system, such as a surround system, a quadraphonic system, a stereophonic system, etc, in the design of electronic filters used in, e.g. virtual reality systems, to simulate sound transmission from a virtual sound source to the ear canals of the listener, or, in the design of an artificial head that is designed so that its Head-related Transfer Functions approximate the Head-related Transfer Functions of the invention as closely as possible in order to make the best possible representation of humans by the artificial head, e.g. to make artificial head recordings of optimum quality.
Patent DE-69524937-D1 (DE)
Inventor: MONCRIEF N
IPC: B65B43/32
Filed: 1995-09-12
Granted: 2002-02-14
Abstract: A method and means for opening a collapsed rectilinear carrier sleeve. As the collapsed sleeve is moved through a packaging machine it is partially opened so that the leading panel extends at an angle to the horizontal. A continuous upward force is then delivered to the leading panel to cause the leading panel to pivot up about its upstream fold line until it reaches the vertical. The collapsed sleeve is partially opened by elevating side flaps connected to an upper panel to cause the upper panel to be elevated. One way of accomplishing this is to cause the upper flaps to ride up over a fixed cam surface while lower flaps connected to a lower panel move under the cam to prevent the lower panel from moving in an upward direction.
Patent DE-69535817-D1 (DE)
Inventor: APTE SATEESH N
IPC: C12N15/74
Filed: 1995-12-26
Granted: 2008-10-02
Abstract: Human immunodeficiency virus (HIV) is the primary etiologic agent for the acquired immune deficiency syndrome (AIDS). HIV exhibits considerable genotypic and phenotypic variability as manifested by different replicative kinetics, susceptibility to serum neutralization, antiviral drug resistance, cytopathic effects, and host-cell range specificity. Infection by HIV leads to progressive deterioration of cell-mediated immune responses making infected patients susceptible to a variety of opportunistic infections, such as pneumocystis carinii pneumonia (PCP), as well as, to the development of tumors such as Kaposi's sarcoma (KS). While the use of live-attenuated viruses to treat HIV infection has been proposed, to date researchers have been unable to demonstrate their efficacy in a clinical setting. The claimed invention addresses this defect by providing therapeutic compositions and methods of treatment employing viral suspensions prepared from cells transfected with a recombinant HIV-1 nef-deficient molecular clone. The HIV-1 nef gene product is required for efficient viral replication and pathogenicity in vivo. Nef may exert its effects through the downregulation of CD4 by endocytosis and lysosomal degradation, although other activities have also been ascribed to this gene product. Accordingly, this gene product was targeted for inactivation and a recombinant HIV-1ELI molecular clone was generated containing an NcoI/XhoI nef deletion. Suspensions comprising viral particles generated from cells transfected with the recombinant clone were prepared and administered to HIV-infected patients. Patients receiving these suspensions displayed a statistically significant reduction in viral burden and increase in CD4<+> lymphocyte counts during the study. The claimed compositions should facilitate the reduction of viral burden and the restoration of CD4<+> lymphocyte levels in HIV-1-infected subjects.
Patent DE-69607670-D1 (DE)
Inventor: MAURICE ALAIN
IPC: F16B45/02
Filed: 1996-02-27
Granted: 2000-05-18
Abstract: The snap buckle consists of a C-shaped metal body (12) having a first end with a male retainer (20), and a second with an articulated pin (14) which turns about a pivot (16) between open and closed positions. The pin has a female retainer (22) at the opposite end of the pivot (16) to cooperate with the male retainer when in the closed position, a return spring (24) which moves the pin towards the closed position, and a coaxial locking sleeve (18) with a second return spring (26). The pin (4) also has a spring-loaded telescopic lock (40) to retain the sleeve in its locked position and which is disengaged by rotating the sleeve.
Patent DE-69619096-D1 (DE)
Inventor: GRAFF PIERRE
IPC: B31F1/07
Filed: 1996-08-13
Granted: 2002-03-21
Abstract: PCT No. PCT/FR96/01281 Sec. 371 Date Apr. 23, 1997 Sec. 102(e) Date Apr. 23, 1997 PCT Filed Aug. 13, 1986 PCT Pub. No. WO97/08386 PCT Pub. Date Mar. 6, 1997The invention concerns an absorbing multi-layer web (10) of at least two layers (12, 14) each including at least one embossed ply (16, 18, 20) made of a creped absorbent paper, having an outer side forming the outer side of the multi-layer web and an inner side, the inner side of the first layer (12) including first and second protrusions (22) and (24) respectively, and the inner side of the second layer (14) including third protrusions (26) nesting between the protrusions (22, 24) of the first layer, the two layers (12, 14) being bonded to each other, characterized in that the first layer (12) is a double ply including of an inner ply (16) of which the inner side includes first and second protrusions (22A) and (24A) respectively, and an outer ply (18) of which the inner side includes first protrusions (22B) and second protrusion (24B). The tops of the protrusions (22A) and (22B) are bonded to each other but not the tops of the protrusions (24A) and (24B).
Patent DE-69619117-D1 (DE)
Inventor: NIESOR ERIC
IPC: C07F9/40
Filed: 1996-07-26
Granted: 2002-03-21
Abstract: PCT No. PCT/EP96/03301 Sec. 371 Date Jan. 28, 1998 Sec. 102(e) Date Jan. 28, 1998 PCT Filed Jul. 26, 1996 PCT Pub. No. WO97/04785 PCT Pub. Date Feb. 13, 1997A method of treating or preventing neoplastic disease and a method of preventing transformation of a normal cell into a tumor cell by mutated ras activities, utilizing a compound of formula I are disclose.
Patent DE-69623057-D1 (DE)
Inventor: HARTLEY L
IPC: C12N9/00
Filed: 1996-06-07
Granted: 2002-09-19
Abstract: Compositions and kits are provided for recombinational cloning. One composition comprises at least one isolated recombination protein and at least one isolated nucleic acid molecule comprising at least a first recombination site containing at least one mutation, wherein said mutation removes one or more stop codons from said recombination site. Another composition comprises at least one isolated recombination protein and at least one nucleic acid molecule comprising at least a first nucleic acid sequence selected from the group consisting of SEQ ID NOs:1-16, a complementary DNA sequence thereto, and an RNA sequence corresponding thereto. A further composition comprises at least one isolated recombination protein and at least one isolated nucleic acid molecule comprising at least a first recombination site containing at least one mutation, wherein said mutation avoids hairpin formation. Other compositions are as further defined in the claims.
Patent DE-69624355-D1 (DE)
Inventor: TRYGGVASON KARL
IPC: C12N15/861
Filed: 1996-05-16
Granted: 2002-11-21
Abstract: The instant invention provides for apparatus and methods for the efficient administration of pharmaceuticals to target cells, tissues and/or organs, for a variety of functional uses.
Patent DE-69624574-D1 (DE)
Inventor: FLAMINIO MARIAROMANO
IPC: B05D5/06
Filed: 1996-07-24
Granted: 2002-12-05
Abstract: A method for coating surfaces in general, and decorating them with powders of various colours characterised by: applying to the surface to be decorated, previously treated for this application, a layer of powdered coating material of colour corresponding to the desired background for the decoration to be obtained, heating the surface treated in this manner to a temperature lower than the baking temperature of the powdered coating material, but sufficient to fix it to the surface to be decorated, applying to the surface prepared in this manner at least one powder of colour corresponding to the coloured motif to be reproduced, distributing it in accordance with the desired pattern of this motif, subjecting the surface treated in this manner to final baking for a time and at a temperature sufficient to securely fix said powder to said surface.
Patent DE-69629409-D1 (DE)
Inventor: NAKANO REIKICHI
IPC: B44C1/24
Filed: 1996-03-15
Granted: 2003-09-18
Abstract: A polyvinyl chloride resin sheet which is excellent in resistance to scratch, wear and slip and hence suitable for use as flooring materials, which has a thickness of 50-500  mu m; an embossed and matted surface of which roughness is 15-25  mu m; and a transmittance of not less than 75%, and which comprises:     (a) polyvinyl chloride; (b) a plasticizer in an amount of 5-35 parts by weight per 100 parts by weight of polyvinyl chloride; and (c) short glass fibers having a diameter of 6-12  mu m and an average length of 0.2-1.0 mm in an amount of 0.5-30 parts by weight per 100 parts by weight of polyvinyl chloride.
Patent DE-69634807-D1 (DE)
Inventor: RINNE TOMMI
IPC: A47C7/02
Filed: 1996-09-20
Granted: 2005-07-07
Abstract: A chair seat cushion which is intended to be placed on the front part of a chair seat, is essentially non-compressible when subjected to load, has a length (L1) which is substantially smaller than the effective length (L0) of the seat (21), so as to enable the rear edge (4) of the cushion to be moved to a position essentially immediately beneath the hip joints of a seated person, at the same time as the front edge (3) of the cushion will be located essentially inwardly of the front edge of the seat (21). The seat cushion has an effective thickness (t2) of from 25-45 mm between the generally flat bottom surface of the cushion and those parts (2) of the upper side of the cushion that support the thighs of the seated person. <IMAGE>
Patent DE-69703935-D1 (DE)
Inventor: KIM JUNG HO
IPC: C07C275/54
Filed: 1997-06-25
Granted: 2001-02-22
Abstract: PCT No. PCT/KR97/00123 Sec. 371 Date Dec. 21, 1998 Sec. 102(e) Date Dec. 21, 1998 PCT Filed Jun. 25, 1997 PCT Pub. No. WO98/00394 PCT Pub. Date Jan. 8, 1998The present invention relates to a novel benzoyl urea derivative which exhibits potent growth-retarding activity against pests and which is represented by formula (I), in which A represents N or CH, and X1 and X2 independently of one another represent hydrogen, fluoro, chloro or bromo.
Patent DE-69718512-D1 (DE)
Inventor: RIGO MASSIMO
IPC: F04B39/00
Filed: 1997-10-17
Granted: 2003-02-20
Abstract: Electric compressor comprising a compression cylinder and the respective head, a valve plate arranged between the head and the body of said cylinder and provided with a gas inlet opening, a silencer arranged at the inlet side of said opening and comprising an elongated portion with an aperture adapted to fit in with said opening. The head is provided externally with a concave recess which is laterally open towards the inner cavity of the compressor, said elongated portion of the silencer being firmly housed in said recess so that the aperture engages the opening in the valve plate in an air-tight, sealed manner. In said recess there is provided a hollow space between said elongated portion and the outer wall, said hollow space being adapted to accommodate an elastic element for locking the silencer in place.
Patent DE-69736115-D1 (DE)
Inventor: ROLF M
IPC: C07K14/79
Filed: 1997-06-18
Granted: 2006-07-27
Abstract: Method for obtaining highly purified transferrin from a partially purified plasma fraction containing transferrin in which the starting fraction is concentrated. Its ionic strength is reduced and then transferrin is adsorbed onto a chromatographic column. Following elution, the transferrin can be further processed through to packaging in final containers. The final purified transferrin product is sterile, at least 95% pure and is substantially free of enveloped and non-enveloped viruses.
Patent DE-69738935-D1 (DE)
Inventor: D AMATO ROBERT J
IPC: A61K45/06
Filed: 1997-11-04
Granted: 2008-10-02
Abstract: The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, thalidomide and various related compounds such as thalidomide precursors, analogs, metabolites and hydrolysis products have been shown to inhibit angiogenesis and to treat disease states resulting from angiogenesis. Additionally, anti-inflammatory drugs, such as steroids and NSAIDs can inhibit angiogenesis dependent diseases either alone or in combination with thalidomide and related compounds. Importantly, these compounds can be administered orally.
Patent DE-69800825-D1 (DE)
Inventor: VEZZANI GIORGIO
IPC: B25B27/02
Filed: 1998-10-06
Granted: 2001-06-28
Abstract: A conventional swaging gripper (90) with two jaws (92) can be applied to the device (82) for swaging metal pipes (100). The closure movement of the jaws (92) which squeeze the pipe (100) is achieved by a hydraulic transmission comprising: a cylinder (44) within which a rod (52) is movable in both directions, one end of the rod emerging from the cylinder (44) through a suitable sealed aperture and to its other end there being coaxially fixed a sealed piston (54) which divides the interior of the cylinder (44) into a first chamber (42) and a second chamber (58) both containing an incompressible liquid, the outer end of the rod carrying means (80) for opening the jaws (92) of the pipe swaging gripper (90), applicable to the pipe swaging device (82), as a result of volume increase of the first chamber (42); a reservoir (34) also containing said incompressible liquid, the reservoir shell having a part (74) deformable elastically within a predetermined range as a result of variation in the liquid quantity within the reservoir (34); a plunger pump (30) to withdraw the liquid contained in the reservoir (34) and to feed it under pressure into the first chamber (42) of the cylinder (44) via a first conduit (36, 46, 48); a second conduit (72) which connects the second chamber (58) of the cylinder (44) to the reservoir (34); a third conduit (53) which connects the first chamber (42) to the reservoir (34) by by-passing the pump (30); manually operable shut-off means (51, 49) provided in the third conduit (53); and elastic return means (55) for returning the rod (52) into the position corresponding to minimum volume of the first chamber (42) of the cylinder (44) when the shut-off means (51, 49) in the third conduit (53) are open. <IMAGE>
Patent DE-69802675-D1 (DE)
Inventor: PIACENTINI SERGIO
IPC: B21C1/12
Filed: 1998-07-27
Granted: 2002-01-10
Abstract: In a system comprising an upstream die plate (12) and a downstream die plate (14) for carrying out plastic processing with reduction of cross section on a moving strip or wire (F) of material, one drawing capstan (16) downstream of an upstream die plate (12), and a further drawing capstan (18) downstream of a downstream die plate (14), possible errors of rotational speed of the upstream capstan (16) with respect to the downstream capstan (18) are detected by measuring the volume of material that passes per unit time at a location upstream of the upstream capstan (16), which is the capstan being controlled, and at a location upstream of the downstream capstan (18), which is the reference capstan. The measurement must be made in the vicinity of the corresponding die plates (12,14)(it is not important whether before or behind). <IMAGE>
Patent DE-69806622-D1 (DE)
Inventor: VERONA GIANCARLO
IPC: A61K8/00
Filed: 1998-04-17
Granted: 2002-08-22
Abstract: Formulations for the prevention and therapy of hair loss and seborrhoea are based on essential oils obtainable through alcoholic distillation of plants which contain the essential oils, combined with salicylic acid and with fatty acids having 10 to 40 carbon atoms.