baber/WOPTO huggingface dataset:
Patent PT-1147179-E (PT)
Title: Human liver progenitors
Inventor: REID LOLA M
IPC: C12N5/10
Filed: 2000-01-19
Abstract: Methods of isolating and cryopreserving progenitors from human liver are disclosed which include processing human liver tissue to provide a substantially single cell suspension comprising progenitors and non-progenitors of one or more cell lineages found in human liver, subjecting the suspension to a debulking step, which reduces substantially the number of non-progenitors in the suspension, and which provides a debulked suspension enriched in progenitors exhibiting one or more markers associated with at least one of the one or more cell lineages; and selecting from said debulked suspension those cells, which themselves, their progeny, or more mature forms thereof express one or more markers associated with at least one of the one or more cell lineages. Among these markers are CD14, CD34, CD38, CD45, and ICAM. Hepatic progenitors are characterized as being 6-15 µ in diameter, diploid, glycophorin A - , CD45 - , AFP +++ , ALB + , ICAM +  and with subpopulations varying in expression of CD14 + , CD34 ++ , CD38 ++ , CD117 + . These progenitor subpopulations have characteristics expected for cells that are particularly useful in liver cell and gene therapies and for extablishing bioartificial organs.
Patent PT-1169297-E (PT)
Inventor: BYONG-SUNG KWAK
IPC: C07C213/02
Filed: 2000-03-09
Abstract: Disclosed is a method for preparing serinol (2-amino-1,3-proanediol). From nitromethane, para-formaldehyde and sodium hydroxide, 1-nitro-1,3-propanediol sodium salt is prepared as a medical intermediate. In a fixed bed, this intermediate is allowed to undergo the continuous hydrogenation of 2-nitro-1,3-propanediol sodium salt and methanol as shown in reaction (1). In addition to being simple, the method is economically favorable and affords the high yield and high purity of serinol.
Patent PT-1190255-E (PT)
Title: Epitopes formed by non-covalent association of conjugates
Inventor: NEW ROGER
IPC: A61K31/195
Filed: 2000-06-27
Abstract: A composition for interacting with a ligand, which composition comprises anon-covalent association of a plurality of distinct conjugates, each conjugate comprising a head group and a tail group, wherein the tail groups of the conjugates form a hydrophobic aggregation and the conjugates are movable within the association so that, in the presence of a ligand, at least two of the head groups are appropriately positioned to form an epitope capable of interacting with the ligand more strongly than each of head groups individually.
Patent PT-1129264-E (PT)
Inventor: JEROME STUBLER
IPC: E01D11/00
Filed: 2000-09-12
Abstract: A reinforcement for a building works structure comprising an assembly of solid wires. The wires are mutually parallel to form a bundle and the reinforcement comprises a sheath made of plastic material enclosing the bundle and providing it with cohesion.
Patent PT-1286896-E (PT)
Title: Collapsible container for transport and storage
Inventor: ORSET OLIVIER
IPC: B65D6/18
Filed: 2001-02-22
Abstract: Collapsible container (1) for transport and storage, which container includes a carrying base part (20), collapsible side walls (30). The side walls (30) are moveably attached to the base part (20). Adjacent side walls (30) are inter-connectable. At least two long side walls (30I and 30II) each are provided with a first and a second horizontal folding line (31 and 32 respectively) by being provided with hinges (3). The first horizontal folding line (31) constitutes the lower end (33) of the side wall (30) at which the side wall (30) connects with the base part (20). The second horizontal folding line (32), which divides the side wall (30) into an upper side wall part (30U) and a lower side wall part (30L), is placed at a distance from the first horizontal folding line (31), between the lower end (33) and upper rim (34) of the side walls (30). The two horizontal folding lines (31 and 32 respectively) are mainly parallel.
Patent PT-1276885-E (PT)
Title: Trophic conversion of obligate phototrophic algae through metabolic engineering
Inventor: KYLE DAVID J
IPC: C12Q1/02
Filed: 2001-04-20
Abstract: Most microalgae are obligate photoautotrophs and their growth is strictly dependent on the generation of photosynthetically-derived energy. In this study it is shown that the microalga Phaeodaclylurn tricornutum can be engineered to import glucose and grow in the dark through the introduction of genes encoding glucose transporters. Both the human and Chlorella kessleri glucose transporters facilitated the uptake of glucose by P. tricornutum, allowing the cells to metabolize exogenous organic carbon and thrive, independent of light. This is the first successful trophic conversion of an obligate photoautotroph through metabolic engineering, and it demonstrates that methods of cell nourishment can be fundamentally altered with the introduction of a single gene. Since strains transformed with the glucose transport genes are able to grow non-photosynthetically, they can be exploited for the analysis of photosynthetic processes through mutant generation and characterization. Finally, this work also represents critical progress toward large-scale commercial exploitation of obligate phototrophic algae through the use of microbial fermentation technology, eliminating significant limitations resulting from light-dependent growth.
Patent PT-1383705-E (PT)
Inventor: KUMAR NEILAN KRISHNA
IPC: B67D1/12
Filed: 2002-04-19
Abstract: A liquid injector system includes a liquid injector ( 10 ) comprising a container ( 11 ) for containing a concentrated liquid and having an opening ( 13 ) which is closed by a valve ( 23 ). The valve ( 23 ) is biased to a closed position by leaf springs ( 28 ) and is opened by engagement by a nozzle. Pressure is applied to the concentrated liquid by means of a manually operable piston ( 19 ) so that, when the valve ( 23 ) is in an open position, at least some of the concentrated liquid is dispensed under pressure from the container ( 11 ).
Patent PT-1381271-E (PT)
Inventor: KURT MEHMET
IPC: A61B5/01
Filed: 2002-04-17
Abstract: This invention relates to an automatic animal training system serving a physical performance improvement and simulation means for the animals of particularly horse, camel or similar animals joining races throughout the world. <IMAGE>
Patent PT-1427817-E (PT)
Title: Multiplication of viruses in a cell culture
Inventor: VORLOP JUERGEN
IPC: C12N5/0784
Filed: 2002-09-11
Abstract: The present invention concerns methods for multiplication of viruses in cell culture in which cells are infected with a virus and after infection the cells are cultured in cell culture under conditions that permit multiplication of the viruses and at the same time targeted additional, at least two-fold, multiplication of the cells. The invention also concerns the use of the viruses so obtained or proteins expressed by them for production of drugs and diagnostic agents.
Patent PT-1446422-E (PT)
Title: Methylated heparin-binding hemagglutinin recombinant mycobacterial antigen, preparation method and immunogenic compositions comprising same
Inventor: MENOZZI FRANCO
IPC: C12N15/09
Filed: 2002-11-18
Abstract: Immunogenic recombinant peptide (I) is the methylated form of an expression product of a nucleic acid (II) that encodes a mycobacterial heparin-binding hemagglutinin antigen (HBHA), especially from Mycobacterium bovis BCG or M. tuberculosis, is new. Independent claims are also included for: (1) processes for preparing (I); (2) recombinant vector that encodes HBHA and at least one recombinant mycobacterial methyltransferase; (3) host cell that harbors a vector of (2); (4) (I) produced by method (1); and (5) immunogenic composition containing any methylated form of HBHA. ACTIVITY : Tuberculostatic. Mice were immunized with native HBHA (5 mu g), 3 times at 2 week intervals. The titer of HBHA-specific immunoglobulin G (IgG) was then 5000, principally IgG1. Ten weeks after the first immunization, the animals were challenged with 10 5> colony-forming units (cfu) of M. tuberculosis and after 6 weeks the number of cfu in various organs was measured. Compared with adjuvant-only controls, the vaccination caused a reduction, in log10 cfu, of 0.94 in liver; 0.85 in spleen and 0.93 in lungs. Equivalent results (not quoted) were achieved with recombinant methylated HBHA. MECHANISM OF ACTION : Vaccine.
Patent PT-1532284-E (PT)
Title: Device for injecting a treatment gas into a molten metal
Inventor: COUDRY DANIEL
IPC: F27D27/00
Filed: 2003-08-27
Abstract: The invention relates to a device ( 8 ) which is used to inject a treatment gas into a molten metal contained in a tank ( 1 ) and which is designed to be fixed in one of the walls of said tank. The inventive device comprises at least one injection nozzle ( 18 ) which is equipped with an end hole ( 19 ). Said device is characterised in that it comprises a mobile means ( 14 ) which can be manoeuvred from outside of the injection device and which is used to unblock the aforementioned end hole of the nozzle.
Patent PT-1554374-E (PT)
Title: Procedure for the large-scale t-lymphocytes culture in a homogeneous system
Inventor: TRASCIATTI SILVIA
IPC: A61K35/12
Filed: 2003-10-06
Abstract: The present invention refers to a procedure for the large-scale amplification of human lymphocytic cell lines for therapeutic use, consisting of a homogeneous culture system. The claimed invention also refers to the production of therapeutic doses of lymphocytic cells cultured homogeneously.
Patent PT-1694626-E (PT)
Title: Purification process for lactide
Inventor: MEERDINK JOHANNES
IPC: C07C55/28
Filed: 2003-12-10
Abstract: The present case relates to a process for the purification of lactide from a crude lactide vapor product stream which process comprises a rectification/condensation step leading to a lactide-enriched condensate.
Patent PT-1562681-E (PT)
Title: Sock
Inventor: LAMBERTZ BODO W
IPC: A41B11/02
Filed: 2003-11-11
Abstract: This invention relates to a sock, in particular to be used of sporting activities, comprising cushioning in the vicinity of the Achilles tendon. Said cushioning is formed by at least two spacer cushion pads (24,25), placed on either side of the Achilles tendon and running alongside the latter.
Patent PT-1563452-E (PT)
Title: A method for the production of an identity card or similar, and an arrangement for the production of such a card.
Inventor: BRODIN PETER
IPC: B42D15/10
Filed: 2003-11-13
Abstract: The present invention relates to a method and to an arrangement for producing an ID document (9) or a like document in which a photograph (2) shall be included in the ID-document and in which the photograph (2) is produced in a digital form and transferred (7) for direct copying into the document (9) while still in its digital form. According to the invention additional information concerning an owner of the ID document (9) is produced in a digital form and transferred for incorporation in the ID document (9) in an electronic form (13).
Patent PT-1454580-E (PT)
Title: Toilet lid with hydraulic closing brake
Inventor: CUTIVET GERARD
IPC: A47K13/10
Filed: 2004-03-02
Abstract: The device has two coaxial hinges, each with two hinge units, where hinge units (14b, 15a) are connected to respective axles by a fixed mechanical connection, and hinge units (14a, 15b) rotate freely on the axles. The axles are placed in a support plate inside the levels, to allow disassembling of a lid and glasses, with 90 degree. Each level in the shape of C is laid out between units (14a, 15a) and units (14b, 15b).
Patent PT-1654485-E (PT)
Title: Poppet type flow control valve
Inventor: MCCAUSLAND ANDREW
IPC: F16K1/12
Filed: 2004-07-20
Abstract: A valve of the invention includes a valve body having an inlet, an outlet, and a flow passage connecting the inlet and outlet, the inlet, the outlet and the flow passage being in general axial alignment within the valve body. A valve seat surrounds the flow passage and a valve closure member is movable towards and away from the valve seat to close and open the valve respectively. The valve closure member is a poppet-type closure member axially mounted to a stem. The stem has a plurality of pistons spaced apart along the length thereof, and the valve body has a plurality of cylinders fixed relative thereto, the pistons each being slidable in a respective cylinder. The valve closure member is movable by varying the pressure in the cylinders. Preferably each of the cylinders has an outlet port through a wall thereof which is exposed when the closure member has moved towards or into a fully open position, pressure within said cylinders dissipating through those outlet ports when the outlet ports are exposed.
Patent PT-1791933-E (PT)
Title: Enzymatic oil-degumming method
Inventor: SOE JORN BORCH
IPC: A23L29/00
Filed: 2005-07-18
Abstract: The invention also encompasses the use of a lipolytic enzyme obtainable from one of the following genera:  Streptomyces, Corynebacterium  and  Thermobifida  in various methods and uses, wherein said lipolytic enzyme is capable of hydrolysing a glycolipid or a phospholipid or transferring an acyl group from a glycolipid or phospholipids to a acyl acceptor. Preferably, the lipolytic enzyme for use in these methods and uses comprises an amino acid sequence as shown in any one of SEQ. ID. No.s 4, 5, 7, 8, 12, 14 or 16 or an amino acid sequence having at least 70% identity therewith or comprises a nucleotide sequence shown as SEQ ID No. 3, 6, 9, 13, 15 or 17 or a nulceotide seqeunce which has at least 70% identity therewith. The present invention also relates to a lipolytic enzyme capable of hydrolysing at least a galactolipid or capable of transferring an acyl group from a galactolipid to one or more acyl acceptor substrates, wherein the enzyme is obtainable from  Steptomyces  species and includes a lipolytic enzyme comprising an amino acid sequence as shown in SEQ ID No. 4 or an amino acid sequence which has at least 60% identity thereto. The enzyme may be encoded by a nucleic acid selected from the group consisting of: 
a nucleic acid comprising a nucleotide sequence shown in SEQ ID No. 3; 
a nucleic acid which is related to the nucleotide sequence of SEQ ID No. 3 by the degeneration of the genetic code; and 
a nucleic acid comprising a nucleotide sequence which has at least 70% identity with the nucleotide sequence shown in SEQ ID No. 3.
Patent PT-2224616-E (PT)
Title: Method of determining transmission rate of control response frame for acknowledging data receipt in a wlan
Inventor: KWON CHANG-YEUL
IPC: H04W28/22
Filed: 2006-02-06
Abstract: A method is provided for determining a transmission rate of a control response frame for acknowledging data receipt in a wireless local area network. The method includes obtaining transmission parameters of a transmitting station from a data transmission frame received from the transmitting station, searching a receiving station for transmission parameters which correspond to the transmission parameters of the transmitting station, determining the transmission rate of the control response frame according to transmission parameters of the receiving station if the transmission parameters corresponding to the transmission parameters of the transmitting station are found in the receiving station, and determining a maximum rate among a set of basic transmission rates to be the transmission rate of the control response frame if the transmission parameters corresponding to the transmission parameters of the transmitting station are not found in the receiving station.
Patent PT-594291-E (PT)
Inventor: SHIBANO MITSUGI
IPC: A61P33/00
Filed: 1993-09-01
Abstract: An intermediate useful in the synthesis of milbemycin derivatives having an ether bond at the 13-position and which is represented by the general formula (IIId) : <CHEM> wherein R represents a methyl group, an ethyl group, an isopropyl group or a sec-butyl group, and R<5> and R<6'> each individually represents a hydrogen atom or a protecting group, and related precursors as well as to a process for producing these intermediates.
Patent PT-654484-E (PT)
Inventor: HETTCHE HELMUT
IPC: A61K47/48
Filed: 1994-10-18
Abstract: Medicament (A) contains thioctic acid or dihydroliponic acid (II) in the form of an inclusion cpd. with a cyclodextrin or deriv.. Medicament (B) contg. (I) or salt and formulated as a granulate, chewable or effervescent tablet or suppository is also claimed. (I) and (II) can be present as the racemate or as the (R)- or (S)-enantiomer. Inclusion cpds. formed with the (R)- and (S)-enantiomers of (I) and (II) are claimed. Pref. medicament (B) as a granulate or tablet contains, in addition to (I) and opt. conventional flavourings, sweeteners and aromas, 0.001-1 pt.wt. binder and 0.001-0.1 pt.wt. flow aid and, in the case of effervescent tablets, 0.05-30 pts.wt. effervescent mixt.; pts.wt. being based on (I). In these granulates and tablets as well as in suppositories (I) can be embedded in a fat, polymer and/or swelling agent. Further, granules may be provided with a coating. beta -cyclodextrin is esp. suitable. When a cyclodextrin deriv. is used, this may conveniently be a methyl, ethyl, carboxymethyl, hydroxyalkyl, dialkylaminoethyl, sulphoalkyl, partially methylated carboxyalkyl, dimerised or branched-chain cyclodextrin.
Patent PT-716001-E (PT)
Inventor: CHAPRONT PIERRE
IPC: B60T8/00
Filed: 1995-11-30
Abstract: The procedure for protection against slipping at the time of measurement of the speed of the railway vehicle involves monitoring the changing acceleration values of the vehicle. The procedure involves a first stage consisting of detecting the start of the vehicle braking and a second stage of detecting the vehicle sliding. The third stage involves increasing the sliding to a set value and monitoring the slipping so that it stabilises. The fourth stage involves detection of the vehicle sliding, and determination of a time during which the measurement of the vehicle displacement is not to be used.
Patent PT-743497-E (PT)
Inventor: KENDALL JOHN HUGH
IPC: A23L7/196
Filed: 1994-08-29
Abstract: Water and wet food granules are fed to a perforated rotating barrel (230) in which the food granules move in a longitudinal direction, the barrel having separately controllable temperature zones (268,270,272,274), and a blower (222) for blowing air past the food granules along a path that passes through perforations in the barrel (230), crosses an inner space within the barrel, and exists through perforations in the barrel.
Patent PT-739773-E (PT)
Inventor: SCHNIERLE MARTIN
IPC: B60N2/24
Filed: 1996-04-15
Abstract: The seat has a tubular frame (3) which is extended in the head rest area and the head rest is integrated in the back rest. The lateral parts of the tubular frame are strengthened by flat reinforcement parts (6) running in the adjustment direction of the back rest. The reinforcement part of the lateral frame is extended downwards via the link axis (4) on the seat frame (2). A gas pressure spring (8) is linked to the extension (7) of the reinforcement part. A limiting bar (17) runs parallel to the gas pressure spring and between the extension of the reinforcement part and the side part (13). The limiting bar limits the adjustment angle of the back rest in a forward direction.
Patent PT-743578-E (PT)
Inventor: RENZ MANFRED
IPC: F24F8/10
Filed: 1996-05-16
Abstract: The clean room system has filter-ventilator units (2), each with at least one fan motor and connected to a power supply network. The filter-ventilator units are connected to each other and to at least one central command unit (16,18) via a bus system (10). The command unit is connected to the bus system via a node (15,19). The bus system is part of a LON network. Each filter-ventilator unit is connected to it via a node (13). The fan motors (3) are electronically commutated d.c. motors, each connected to its corresp. node (13) via a motor controller (4,5), which may benefit from having a bridge circuit and/or a microcontroller.
Patent PT-780064-E (PT)
Inventor: DEAN TODD
IPC: A43B17/02
Filed: 1996-12-20
Abstract: A hydrodynamic pad including fluid-filled inner and outer bladders interconnected by fluid channels and configured such that displacement of fluid from the center of pressure distribution generated by foot impact radiates from the inner bladder outwardly to the outer bladder through one or more of the fluid channels causing the outer bladder to expand to an expanded condition. The expanded outer bladder seats the wearer's heel in the hydrodynamic pad, thereby stabilizing the foot of the wearer, and the controlled flow of fluid through the fluid channels to the outer bladder dissipates the impact loads, thereby cushioning the wearer's heel. When the pressure is released from the inner bladder, by lifting the wearer's heel, the expanded outer bladder forces at least a portion of the displaced fluid to the inner bladder, such that the hydrodynamic pad is reinitialized. <IMAGE>
Patent PT-774378-E (PT)
Inventor: MAGYAR GEORGES
IPC: B60P3/22
Filed: 1996-11-15
Abstract: The tank for the thermally insulated transporter vehicle comprises a main cylindrical section (1) forming the base of the tank, and the greater part of the structure of the tank. The cylinder is closed at the end by end plates. The upper section of the tank includes a seating (3) arranged transversely, allowing the installation of indicator lights. The indicator lights may include a central light (4) connected to the vehicle brake lights, and two side lights (5,6) connected to the direction indicators and serving as repeaters. The tank may be covered in an insulation material such as fibreglass (RTM) foam, surrounding a tubular envelope of stainless steel.
Patent PT-854826-E (PT)
Inventor: DULLEMEN MARLIES VAN
IPC: B65D83/04
Filed: 1996-08-22
Abstract: PCT No. PCT/NL96/00332 Sec. 371 Date Jun. 3, 1998 Sec. 102(e) Date Jun. 3, 1998 PCT Filed Aug. 22, 1996 PCT Pub. No. WO97/08078 PCT Pub. Date Mar. 6, 1997An apparatus for dispensing pills from a blister pack in which cavities containing pills are distributed, comprises a lower part for supporting the pack in a ring-shape and an upper part fitting onto the lower part and surrounding the blister pack together with the lower part. The lower part and/or upper part includes at least a passage opening with which a pill to be dispensed can be aligned. A push out element can be positioned in line with the various pills in the blister pack and the passage opening and is operable for pushing out the pill to be dispensed through the passage opening. The lower and upper parts are substantially ring-shaped and the push out element is positioned on the inner side of the ring and is moveable outwardly for the push out action.
Patent PT-1011448-E (PT)
Inventor: ORTEN BIRGER
IPC: A61B7/04
Filed: 1996-11-14
Abstract: The pick-up head (1) with an acousto-electrical transducer (4) for converting sound vibrations to electrical signals, comprises as characterizing features a sound influencing bell (2) arranged around a slender peg (3) bonded directly to the transducer (4), and the sound influencing bell (2) delimits a listening area on a body surface and influences to a predetermined degree and in a predetermined manner, by means of internal reflection and/or absorption, the direct sound picked up by the slender center peg (3). The bell (2) is acoustically decoupled from the center peg (3).
Patent PT-943079-E (PT)
Inventor: ROCH MATHIAS
IPC: G01L5/00
Filed: 1996-12-04
Abstract: According to the method suggested, the mast is submitted to an increasing force, and both this force and the deflection path are correlated to establish a characteristic load line. After it has been loaded, the mast is again relieved from the load, a characteristic load relief line is determined and the return force is correlated to the decreasing return path. The finds related to the mast solidity and anchorage are based on the tracing of the characteristic load relief line and the comparison with the characteristic load line.