Patent SG-11201811680V-A (SG)
Title: Compositions useful in the prevention and/or treatment of osteoarticular inflammation and pain and cartilage damage
Inventor: BOMBARDELLI EZIO
IPC: A61K36/63
Filed: 2017-06-28
Abstract: WO 18/00 2144 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 04 January 2018 (04.01.2018) W I PO I PCT mu °million OH oI0IIIIIIII1101OHDIDHoIIII111111 OIIIIII (10) International Publication Number WO 2018/002144 Al (51) International Patent Classification: A61K 36/758 (2006.01) A61K 36/28 (2006.01) A61K 36/87 (2006.01) A61K 36/63 (2006.01) A61K 36/899 (2006.01) A61K 31/192 (2006.01) A61K 36/9068 (2006.01) A61K 31/7008 (2006.01) A61K 36/185 (2006.01) A61P 29/00 (2006.01) (21) International Application Number: Published: — with international search report (Art. 21(3)) PCT/EP2017/066002 (22) International Filing Date: 28 June 2017 (28.06.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 102016000067621 29 June 2016 (29.06.2016) IT (71) Applicant: INDENA S.P.A. [IT/IT]; Viale Ortles, 12, 20139 MILANO (IT). (72) Inventor: BOMBARDELLI, Ezio; Via Gabetta, 13, 27027 GROPELLO CAIROLI (PV) (IT). (74) Agent: BERTUCCIO, Silvia; BIANCHETTI BRACCO MINOJA S.r.1., Via Plinio, 63, 20129 MILANO (IT). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (54) Title: COMPOSITIONS USEFUL IN THE PREVENTION AND/OR TREATMENT OF OSTEOARTICULAR INFLAM- MATION AND PAIN AND CARTILAGE DAMAGE (57) : The present invention relates to compositions comprising: a) a Vitis vinifera extract in free form or in the form of a complex with phospholipids, or a Punica granatum extract; and b) a lipophilic extract of Zingiber officinale; and c) a lipophilic extract obtained from plants containing polyunsaturated fatty acid isobutylamides selected from the group consisting of Echinacea spp. extract or Zanthoxylum spp. extract or Acmella oleracea (or Spilanthes oleracea) extract; and d) an unsaponifiable fraction of olive oil and/ or corn oil; or e) N-acetyl glucosamine; or f) diacerein; and their use in the prevention and/or treatment of osteoarticular inflammation and pain, and cartilage damage.