baber/WOPTO huggingface dataset:
Patent AU-2019326353-A1 (AU)
Title: Autonomously moveable storage units and wheelchair storage systems
Inventor: MOORE DOUGLAS A
IPC: A45C13/00
Filed: 2019-08-16
Abstract: An autonomously moveable storage unit includes one or more processors, a storage container configured to contain a stored item, a moveable base coupled to the storage container and communicatively coupled to the one or more processors, and one or more memory modules communicatively coupled to the one or more processors. The one or more memory modules store logic that, when executed by the one or more processors, cause the autonomously moveable storage unit to actuate the moveable base to automatically move the autonomously moveable storage unit from a docked position coupled to the wheelchair to an undocked position uncoupled from the wheelchair, and actuate the moveable base to automatically move the autonomously moveable storage unit from the undocked position to the docked position.
Patent AU-2019333921-A1 (AU)
Title: Method and system for indexing of time-series data
Inventor: RYAN DAVID
IPC: G06F16/30
Filed: 2019-09-03
Abstract: A method is disclosed for maintaining an index (210) of time-series data records held in a data store (118). The index has a binary tree structure of nodes, including a root node (400) representing a maximal time period and zero or more non-root nodes. Each non-root node is a leaf node (402) or an inode (406) which comprises a data structure (300) including a start-time field (304) and an end-time field (306) defining a time range represented by the non-root node. Inodes also include reference fields (316, 318) identifying one or both of a first child node representing a first time sub-range and a second child node representing a second time sub-range.
Patent AU-2019335409-A1 (AU)
Title: Hybrid amphotericin B derivatives with reduced toxicity
Inventor: BURKE MARTIN D
IPC: A61P31/10
Filed: 2019-09-06
Abstract: Disclosed are derivatives of amphotericin B (AmB) characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions comprising the AmB derivatives, therapeutic methods of using the AmB derivatives and methods of making the AmB derivatives.
Patent AU-2019336424-A1 (AU)
Title: Method for refining non-petroleum-based ethylene glycol
Inventor: YUAN YI
IPC: C07C29/76
Filed: 2019-09-03
Abstract: Provided in the present invention is a method for refining non-petroleum-based ethylene glycol, wherein impurities having a boiling point close to that of ethylene glycol are separated. In the described method, C
Patent AU-2019337805-A1 (AU)
Title: Wicking element for aerosol delivery device
Inventor: HEJAZI VAHID
IPC: A24F47/00
Filed: 2019-09-10
Abstract: An aerosol delivery device includes an outer housing, a reservoir containing a liquid, a heater configured to vaporize the liquid, and a liquid transport element configured to provide the liquid to the heater. The liquid transport element includes a rigid monolith. At least a portion of the rigid monolith is substantially cylindrical. The cylindrical portion has an exterior surface and a longitudinal axis. The exterior surface has at least one discontinuity.
Patent AU-2019361983-A1 (AU)
Title: Diagnostic and therapeutic methods for sarcomatoid kidney cancer
Inventor: SCHIFF CHRISTINA
IPC: A61K39/00
Filed: 2019-10-17
Abstract: The present invention provides diagnostic methods, therapeutic methods, and compositions for the treatment of cancer (e.g., kidney cancer (e.g., renal cell carcinoma (RCC)). The invention is based, at least in part, on the discovery that expression levels of one or more biomarkers described herein in a sample from an individual having cancer can be used in methods of predicting the therapeutic efficacy of treatment with a VEGF antagonist (e.g., an anti-VEGF antibody, (e.g., bevacizumab) or a VEGFR inhibitor (e.g., a multi-targeted tyrosine kinase inhibitor (e.g., sunitinib, axitinib, pazopanib, or cabozantinib))) and a PD-L1 axis binding antagonist (e.g., a PD-L1 binding antagonist (e.g., anti-PD-L1 antibody, e.g., atezolizumab (MPDL3280A)) or a PD-1 binding antagonist (e.g., anti-PD-1 antibody)), or with an angiogenesis inhibitor (e.g., a VEGF antagonist (e.g., a VEGFR inhibitor, (e.g., a multi-targeted tyrosine kinase inhibitor (e.g., sunitinib, axitinib, pazopanib, or cabozantinib)))).
Patent AU-2019362215-A1 (AU)
Title: Transparent covering having anti-reflective coatings
Inventor: WILSON STEPHEN S
IPC: B32B7/12
Filed: 2019-10-03
Abstract: A transparent covering affixable to a substrate includes a stack of two or more lenses, an adhesive layer interposed between each pair of adjacent lenses from among the two or more lenses, a first anti-reflective coating on a first outermost lens of the stack, and a second anti-reflective coating on a second outermost lens of the stack opposite the first outermost lens. The first anti-reflective coating has a first design wavelength range, and the second anti-reflective coating has a second design wavelength range that is different from the first design wavelength range.
Patent AU-2019364157-A1 (AU)
Title: A locking device
Inventor: JENSEN LARS
IPC: E05B15/00
Filed: 2019-10-18
Abstract: A locking device (1), comprising: - a latch bolt arrangement (2), which is movable into at least a first and a second latch bolt position, said latch bolt arrangement (2) comprising a first follower arm engagement part (7); - a first follower arrangement (8) configured for transferring a motion to the latch bolt arrangement from a first unlocking device which can be connected to the first follower arrangement (8), wherein said first follower arrangement (8) comprises a first follower arm (11) which comprises a latch bolt engagement part (13) which is configured to at least in some positions of the first follower arm (11) contact the first follower arm engagement part (7) of the latch bolt arrangement (2), whereby the latch bolt arrangement (2) can be pushed by a movement of the first follower arm (11) such that the latch bolt arrangement (2) is moved from the first latch bolt position to the second latch bolt position; and - a locking arm (15), wherein said locking arm (15) further comprises a locking arm catch (19), whereby said locking arm (15) can be moved from the first locking arm position to the second locking arm position by pushing said locking arm catch (19), and wherein the first follower arm (11) further comprises a locking arm catch engagement part (21) which will push the locking arm catch (19) for moving the locking arm (15) towards the second locking arm position when the first follower arm (11) is moved for pushing the latch bolt arrangement (2) to the second latch bolt position.
Patent AU-2019367015-A1 (AU)
Title: Flat drill
Inventor: LIN JIE
IPC: B27G15/00
Filed: 2019-09-26
Abstract: A flat drill (100). The flat drill (100) comprises: a handle body (10); a cutting and chip removal part (20) which is axially provided from one end of the handle body (10) and is substantially in a flat shape; and a threaded guide part (30) which is axially provided from one end of the cutting and chip removal part (20). The cutting and chip removal part (20) has two longitudinal wing parts (23); the two longitudinal wing parts (23) are provided to be rotationally symmetric with respect to a longitudinal central axis (O) of the flat drill (100), and a cutting blade (21a) is formed, by each longitudinal wing part (23), at the end of the cutting and chip removal part (20) where the threaded guide part (30) is formed by extension; an angle is formed between a direction inclined from a rotation track surface generated by the cutting blade (21a) during rotation of the flat drill (100) towards the handle body (10) and the longitudinal central axis (O), the angle ranging from 84 degrees to 86 degrees. The torque generated by the flat drill during collision is small, so that the integrity of a cutting blade can be protected.
Patent AU-2019376628-A1 (AU)
Title: Modified double stranded oligonucleotides
Inventor: FOSTER DONALD
IPC: C12N15/113
Filed: 2019-11-05
Abstract: One aspect of the present invention relates to double-stranded RNA (dsRNA) agent capable of inhibiting the expression of a target gene. Other aspects of the invention relate to pharmaceutical compositions comprising these dsRNA molecules suitable for therapeutic use, and methods of inhibiting the expression of a target gene by administering these dsRNA molecules,
Patent AU-2019392572-A1 (AU)
Title: Dispenser latching system
Inventor: CUNEFARE KENNETH A
IPC: A47K10/32
Filed: 2019-12-04
Abstract: A dispenser comprising a body with a front side and a back side with the front side movably attached to the back side by a hinge, wherein the hinge includes pin receiving openings and the hinge is configured to move the front side between an open position and a closed position; and a locking device including pins and a pin housing for each of the pins and being configured to allow respective movement of the pins between a first pin position and a second pin position; and a dispenser key configured to magnetically move the pins from the first pin position to the second pin position to allow the front side to move from the closed position to the open position.
Patent AU-2019394974-A1 (AU)
Title: Crystalline forms of a compound for treating or preventing gout or hyperuricemia
Inventor: YAN SHUNQI
IPC: C07D307/80
Filed: 2019-12-05
Abstract: Described herein are crystalline forms of (3,5-dibromo-4-hydroxyphenyl)(2-(1-hydroxyethyl)benzofuran-3-yl-4,5,6,7-
Patent AU-2019408452-A1 (AU)
Title: Sealed electric plug
Inventor: ZHAO CHANGCHUN
IPC: H02G1/14
Filed: 2019-02-01
Abstract: A sealed electric plug (100) comprises: one or more temperature sensors (120a, 120b) used to monitor a temperature inside the electric plug (100); a data cable (166) housed within a blocking enclosure (162) used to block electric noise so as to precisely acquire and transmit temperature data; and a housing or a supporting member (130) used to receive the one or more temperature sensors (120a, 120b) and capable of being inserted into an internal casing (170) of the electric plug (100) and positioned near one or more pins (102, 104, 106). One or more sealing members (910) can be placed at the one or more pins (102, 104, 106), the internal casing (170), and regions at connections between wires of the data cable (166), thereby insulating the internal casing (170) from air, moisture and particles.
Patent AU-2019462982-A1 (AU)
Title: Method and apparatus for motion information storage
Inventor: GAO HAN
IPC: H04N19/167
Filed: 2019-08-26
Abstract: A motion information storing method comprises: determining a distance between a sample set in the current block and the common boundary; and comparing the distance with a threshold to determine whether third motion information is stored for the sample set, wherein the third motion information is derived by the first motion information and the second motion information
Patent AU-2019478722-A1 (AU)
Title: Non-pnuematic tire spoke with improved elastomeric joint body
Inventor: MILES KEVIN CORBETT
IPC: B60C7/18
Filed: 2019-12-16
Abstract: An improved spoke (100) for a tire (10) attaching an outer tread to a hub (12), the spoke(lOO) having a spoke element possessing spoke element reinforcements, the spoke element joined by a joint body (114) comprised of an elastomer connecting the spoke element to an outer compliant band (200) where the joint body (114) possesses an improved profile for increased robustness.
Patent WO-2020198813-A1 (WO)
Inventor: LANG JEFFREY DAVID
IPC: B33Y10/00
Filed: 2020-04-06
Abstract: A method of manufacturing a multi material device for heat transfer, and a multi material device is disclosed comprising: depositing, by an additive manufacturing technique, a first material on to a scaffold; depositing, by an additive manufacturing technique, a second material onto at least part of the first material, wherein, one of the first or second material is a heat transfer material having a first thermal conductivity, a first chemical resistance and a first erosion resistance and the other is a rugged material of a second thermal conductivity, a second chemical resistance and a second erosion resistance, such that the second thermal conductivity is lower than the first thermal conductivity and at least one of the second chemical resistance or second erosion resistance is higher that the respective first chemical resistance or first erosion resistance.
Patent WO-2021000020-A1 (WO)
Inventor: STRETCH STEPHEN ANDREW
IPC: B03C1/02
Filed: 2020-07-02
Abstract: A method of beneficiating iron ore streams, the method comprising the steps of sizing an iron ore stream to provide a fines fraction of less than 3.0 mm diameter particle size and contacting the fines fraction with a magnetic field and magnetically separating the fines fraction into a concentrate stream and a tailings stream.
Patent AU-2020204600-A1 (AU)
Title: Plasma kallikrein binding proteins
Inventor: SEXTON DANIEL J
IPC: C07K16/18
Filed: 2020-07-09
Abstract: PLASMA KALLIKREIN BINDING PROTEINS 
ABSTRACT 
Plasma kallikrein binding proteins and methods of using such proteins are described.
Patent AU-2020210182-A1 (AU)
Title: Liposomal Particles, Methods of Making Same and Uses Thereof
Inventor: MIRKIN CHAD A
IPC: A61K8/14
Filed: 2020-07-28
Abstract: Liposomes termed as small unilamellar vesicles (SUVs), can be synthesized in the 20-50 nm 
size range, but encounter challenges such as instability and aggregation leading to inter
particle fusion. This limits their use as a therapeutic delivery agent. Increasing the surface 
negative charge of SUVs, via the attachment of anionic entities such as DNA/RNA, increases 
the colloidal stability of these vesicles. Additionally, the dense spherical arrangement and 
radial orientation of nucleic acids exhibits unique chemical and biological properties, unlike 
their linear counterparts. These liposomal particles, are non-toxic and though anionic, can 
efficiently enter cells without the aid of ancillary cationic transfection agents in a non
immunogenic fashion. These exceptional properties allow their use as delivery agents for 
gene regulation in different therapies and offer an alternative platform to metal core spherical 
nucleic acids.
Patent AU-2020217793-A1 (AU)
Title: Methods, systems, and kits for treating inflammatory disease targeting IL18R1
Inventor: BILSBOROUGH JANINE
IPC: A61K38/00
Filed: 2020-02-07
Abstract: Described herein are methods, systems, compositions, and kits useful for the diagnosis and/or treatment of a disease or condition in a subject. The present disclosure relates to methods and systems for identifying and stratifying patients suitable for treatment with an IL18R1 modulator, as described herein.
Patent AU-2020227008-A1 (AU)
Title: A Valve and a Fluid System
Inventor: ROBERTS DAVID JOHN
IPC: E21B34/00
Filed: 2020-08-31
Abstract: The present invention a valve (19) adapted to inject fluid into, and abstract 
fluid from a reservoir (13). The valve comprises a housing (33) having a first 
end (23) adapted to be secured to a first pipe (21), and a second end (27) 
adapted to be in fluid communication with a pump (25). The valve also 
comprises a sleeve (35) slidingly retained in the housing. The sleeve is 
movable relative to the housing between a first position wherein the valve is in 
an injection mode for injecting fluid into the reservoir, and a second position 
wherein the valve is in an abstraction mode for abstracting fluid from the 
reservoir. The present invention also provides a fluid system incorporating 
the valve.
2/5 
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Figure 2
Patent AU-2020237513-A1 (AU)
Title: Result determination in an immunoassay by measuring kinetic slopes
Inventor: REN PETER YAN-GUO
IPC: G01N33/558
Filed: 2020-03-12
Abstract: A system including a sample receptacle configured to receive a test sample and a test strip coupled to the sample receptacle is provided. The test strip configured to generate a signal based on a concentration of a target analyte in the test sample. The system also includes a detector to generate a transduced signal based on the signal and a computer to receive a transduced signal. The computer further determines the concentration of the target analyte in the test sample. For this, the computer retrieves the transduced signal from the detector at multiple time points to determine a signal rate based on a signal value for the time points, and to determine the concentration of the target analyte based on the signal rate and a model. A method and a non-transitory, computer-readable medium storing instructions to use the above system are also provided.
Patent AU-2020250240-A1 (AU)
Title: Dry lubricator for plastic and stainless steel surfaces
Inventor: MORALES ARRIAGA FABIOLA
IPC: C10M169/00
Filed: 2020-10-08
Abstract: A dry lubricant for conveyor belts and other surfaces set for lubricating through 
direct application via a nozzle is disclosed. Lubricants including a homogeneous mixture 
of fatty acids, a hydrocarbon such as a mineral oil, a sorbitan ester, and a polyglycol, which 
are substantially-free of water are disclosed. Methods of using the lubricants in dry and 
semi-dry modes are further disclosed.
Patent AU-2020262117-A1 (AU)
Title: Cell culture medium for eukaryotic cells
Inventor: XUE WEI
IPC: C07K14/71
Filed: 2020-04-22
Abstract: Cell culture media are provided herein as are methods of using the media for cell culture and protein production from cells.
Patent AU-2020275111-A1 (AU)
Title: Bone punch instrument and method for creating a bone tunnel
Inventor: EGGLI STEFAN
IPC: A61B17/16
Filed: 2020-05-10
Abstract: A bone punch instrument and a method are proposed for creating a bone tunnel in target bone. The bone punch instrument is configured to remove of a bone plug out of the target bone. By removing the bone plug, the bone tunnel in the target bone can be created. The punch instrument comprises an impaction handle and punch head having a bore. The punch head comprises a cutting edge arranged circumferentially around the bore at a cutting end of the punch head. By using of the punch instrument, a bone plug can be retrieved without creating bone drilling debris. Furthermore, the bone plug can be retrieved as a solid piece of graft, to be used to as a graft at another site in the body thereby promoting healing and reducing recovery time after surgery.
Patent AU-2020289838-A1 (AU)
Title: Eutectic formulations of Cyclobenzaprine hydrochloride
Inventor: NEBULONI MARINO
IPC: A61P21/02
Filed: 2020-12-17
Abstract: The present invention relates to pharmaceutical compositions and methods of manufacturing 
the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol.
Patent AU-2020290516-A1 (AU)
Title: Compositions and methods for biological delivery vehicles
Inventor: AHMAD MUBHIJ
IPC: A61K48/00
Filed: 2020-06-12
Abstract: Delivery vehicles comprising lipid nanoparticles for the administration of therapeutics, as well as methods of making and using the same for the delivery of therapeutics to epithelial cells, such as those within mucus-containing environments, are provided. The provided nanoparticles comprise ionizable lipids and/or cationic lipids, such as MVL5, MC2, CL1H6, or DODMA, phospholipids, and bile salts. Methods for the delivery of therapeutics, particularly nucleic acid therapeutics, to epithelial cells in the gastrointestinal tract using said delivery vehicles are also provided.
Patent AU-2020297771-A1 (AU)
Title: Heterocyclic derivatives and use thereof
Inventor: ZHOU ZUWEN
IPC: A61P9/12
Filed: 2020-06-15
Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
Patent AU-2020298574-A1 (AU)
Title: Stimulation apparatus
Inventor: BUDDHA RUSHIDEV
IPC: A61N1/18
Filed: 2020-07-02
Abstract: A medical apparatus for a patient comprises an external system and an implantable system. The external system is configured to transmit one or more transmission signals, each transmission signal comprising at least power or data. The implantable system is configured to receive the one or more transmission signals from the external system, and to deliver stimulation energy to the patient. Methods of delivering stimulation energy are also provided.
Patent AU-2020313914-A1 (AU)
Title: Therapeutic constructs for co-delivery of mitotic kinase inhibitor and immune checkpoint inhibitor
Inventor: YANTASEE WASSANA
IPC: C07K16/28
Filed: 2020-07-13
Abstract: Disclosed herein are therapeutic constructs including a delivery particle, at least one mitotic kinase inhibitor, and at least one immune checkpoint inhibitor. Also disclosed are therapeutic constructs including a mitotic kinase inhibitor, an immune checkpoint inhibitor, and a chemical linker. These therapeutic constructs cause cancer death by both therapeutic and immune effects and promote targeted delivery of more therapeutics to the surviving cancer cells in a positive feed-back loop. They enhance therapeutic index of free drugs and can be used intratumorally or systemically. This strategy can treat broad cancer types and is particular useful for cancer without obvious receptors for cancer- targeted delivery of otherwise toxic therapeutics.
Patent AU-2020316427-A1 (AU)
Title: Horizontal connector system and method
Inventor: SHIRANI ALIREZA
IPC: E21B17/02
Filed: 2020-07-22
Abstract: An apparatus includes a flowline connector having an inboard pipe and an outboard assembly. The outboard assembly includes a frame and an outboard pipe moveable within the frame to allow the outboard pipe to be moved toward the inboard pipe. The outboard assembly also includes a profile pipe in which the outboard pipe is received, and the profile pipe and the outboard pipe are connected to move together. The profile pipe includes at least one guide to change pitch or yaw of the outboard pipe to direct the outboard pipe toward alignment with the inboard pipe as the outboard pipe is moved within the frame toward the inboard pipe. Additional systems, devices, and methods are also disclosed.
Patent AU-2020333968-A1 (AU)
Title: Cleavage of single stranded DNA having a modified nucleotide
Inventor: GARDNER ANDREW F
IPC: C12Q1/6806
Filed: 2020-08-21
Abstract: Methods are provided that, for example, include (a) combining ssDNA containing a modified nucleotide (e.g., a ssDNA with a modified nucleotide proximate to its 5'end) with a DNA cleavage enzyme capable of cleaving the ssDNA at the modified nucleotide (e.g., to generate a first ssDNA fragment having a 3'OΗ and a second ssDNA fragment having the modified nucleotide); wherein the ratio of enzyme to DNA substrate is less than 1:1 molar ratio (m/m); and (b) cleaving at least 95% of the ssDNA at the modified nucleotide. In some embodiments, a method may comprise (a) combining (i) a ssDNA comprising a modified nucleotide (e.g., proximate to its 5'end) with (ii) a DNA cleavage enzyme capable of cleaving the ssDNA at the modified nucleotide (e.g., to generate (after cleavage) a first ssDNA fragment having a 3'OΗ and a second ssDNA fragment comprising the modified nucleotide) wherein the ratio of enzyme to DNA substrate is less than 1:1 molar ratio and cleaving at least 95% of the ssDNA at the modified nucleotide. In some embodiments, methods provided herein may include (a) combining (i) a ssDNA (1) immobilized on a substrate and (2) comprising a modified nucleotide with (ii) a ssDNA cleaving enzyme capable of cleaving the ssDNA at the modified nucleotide (e.g., to generate (after cleavage) a first ssDNA fragment having a 3'OΗ and a second ssDNA fragment comprising the modified nucleotide); and (b) cleaving the immobilized ssDNA to release the second single stranded DNA fragment from the substrate. At least 95% (m/m) of an ssDNA comprising a modified nucleotide may be cleaved in less than 60 minutes.