baber/WOPTO huggingface dataset:
Patent ES-2292488-T3 (ES)
Title: Derivados de la urea, como agentes antiinflamatorios.
Inventor: BREITFELDER STEFFEN
IPC: A61P3/10
Filed: 2000-11-16
Granted: 2008-03-16
Abstract: Compuestos de la fórmula (I): en donde, G, es fenilo o piridinilo sustituido por una o más R1, R2, ó R3; Ar, es 1-naftilo; L, es: C(O)CH2-, >C(O), O, ó CH2; Q, es: fenilo, pridinilo, pirimidinilo, imidazolilo, tetrahidro-piranilo, morfolino, tiomorfolino, sulfóxido de tiomorfolino, piperidinilo, piperidinonilo, ó sulfóxido de pentametileno, los cuales se encuentran opcionalmente sustituidos con uno o tres amino, mono-, ó (fenil-alquil-C1-3)amino, metilo, etilo, metoxi, etoxi, metoximetilo ó etoximetilo; cada R1, es, de una forma independiente; alquilo C3-5 ramificado ó no ramificado, opcionalmente parcialmente o totalmente halogenado, y cada R2, es, de una forma independiente: un alquilo C1-6-ramificado ó no ramificado, opcionalmente parcialmente o totalmente halogenado, acetilo, aroílo, alquilo C1-4 ramificado ó no ramificado, opcionalmente parcialmente o totalmente halogenado, halógeno, metoxicarbonilo o finilsulfonilo; alcoxi C1-6, hidroxi, amino, ó mono- ó di-(alquil-C1-4)-amino, ciano, halógeno; OR6; nitro; ó mono- ó di-(alquil-C1-4)amino-S(O)2, opcionalmente parcial-mente o totalmente halogenado, ó H2NSO2; cada R3, es, de una forma independiente: hidrógeno, alquilo C1-3 ó alcoxi C1-3, cada uno, opcionalmente parcialmente o totalmente halogenado, o parcialmente sustituido con dietilamino; CH3C(O)NH-, R22O-; R23R24NC(O)-; R26C(O)N(R21)- ó R26C(O)-CH2(R21)-; R6, es un: alquilo C1-4 ramificado ó no ramificado, opcionalmente parcialmente o totalmente halogenado y opcionalmente sustituido con R26; R21, es: hidrógeno ó alquilo C1-3 ramificado ó no ramificado, opcionalmente parcialmente o totalmente halogenado; R22, es: hidrógeno, alquilo C1-6 ramificado ó no ramificado, opcionalmente sustituido por carbonilamino-mono- ó di-alquilo-C1-3, ó amino-mono- ó di-alquilo-C1-3 ó en donde, el citado alquilo C1-6 opcionalmente parcialmente o totalmente halogenado y opcionalmente interrumpido por uno o más O, N ó S, fenilo, piridina, mono- ó di-alquilo C0-4 ramificadoo no ramificado, opcionalmente parcialmente o totalmente halogenado y alquilamino; R23 y R24, son H ó, R23 y R24, tomadas conjuntamente, forman opcionalmente morfolino; R26, es alquilamino-mono- ó di-C0-4, ramificado o no ramificado, y X, es O; y las sales ó ésteres farmacéuticamente aceptables de éstos.
Patent ES-2241676-T3 (ES)
Title: Pirazolcarboxamidas y pirazoltiamidas como fungicidas.
Inventor: WALTER HARALD
IPC: A01N43/56
Filed: 2000-11-11
Granted: 2005-11-01
Abstract: Una pirazolcarboxamida de fórmula I en donde X es oxígeno; y R1 es alcoxi(C1-C3)-alquilo C1-C3 o haloalcoxi(C1-C3)- alquilo C1-C3; R2 es haloalquilo C1-C3; y R3 es fluor, cloro o bromo, o en donde X es azufre; y R1 es alquilo C1-C3, haloalquilo C1-C3, alcoxi(C1-C3)- alquilo C1-C3 o haloalcoxi(C1-C3)-alquilo C1-C3; R2 es haloalquilo C1-C3; y R3 es halógeno.
Patent ES-2251445-T3 (ES)
Inventor: FOMPERIE LIONEL
IPC: H01B3/30
Filed: 2001-05-14
Granted: 2006-05-01
Abstract: The invention provides nanocomposites comprising a clay and an organic compound, in which the clay is a clay bridged by a metal compound, preferably iron oxide and/or aluminum oxide. The organic compound is preferably a polymer. The clay-based nanocomposites of the invention have good mechanical properties and good heat resistance. The invention also provides cables comprising such a nanocomposite, preferably in their sheath or outer coating. Finally, the invention provides a process for producing said nanocomposite. <IMAGE>
Patent ES-2236179-T3 (ES)
Inventor: HEINEN ADRIANUS JOHANNES
IPC: B60L11/18
Filed: 2001-01-26
Granted: 2005-07-16
Abstract: The invention relates to a wheel provided with electric driving means in the wheel, control, measuring and operating means in the wheel for operating the electric driving means and data communication means in the wheel.  Additionally the invention relates to a method for coordinating at least two of such wheels attached to one vehicle.  Additionally the invention relates to a wheel strut provided with vehicle attachment means for attaching the wheel strut to a vehicle, and wheel attachment means for attaching a wheel to the wheel strut, in which the wheel attachment means are rotatable about the longitudinal axis with respect to the vehicle attachment means and in which the wheel strut is provided with driving means for rotating the wheel attachment means.  The invention also relates to a wheel according to the invention provided with a wheel strut according to another aspect of the invention.
Patent ES-2231503-T3 (ES)
Inventor: SHACKELFORD HOWARD L
IPC: A61B17/32
Filed: 2001-05-29
Granted: 2005-05-16
Abstract: A retractable surgical blade includes a handle defining a channel and a surgical blade member. The handle has a front portion and a back portion. The front portion defines a channel which confines the surgical blade member. The back portion includes a front wall and may be solid. The surgical blade member includes a slider to which is secured a surgical blade. The slider has a portion which engages the channel so that the surgical blade member can move from a cutting position in which the surgical blade projects from the handle and can be employed in a surgical procedure to a parked position in which the surgical blade is disposed in the channel. When in the parked position, the surgical blade is unable to cut or stab persons associated with the surgical procedure. The device may include a locking device to lock the surgical blade member in the parked position. An associated method of performing a surgical procedure is also disclosed.
Patent ES-2316451-T3 (ES)
Inventor: PIND PETER FRODE
IPC: B01D53/84
Filed: 2001-06-26
Granted: 2009-04-16
Abstract: A method and an equipment for monitoring the syntrophic relations between different parts of a bacterial consortium in the process fluid of a biological process plant, such as a biological gas plant or waste water treatment plant, through a chromatographic measurement of the content of the individual volatile fatty acids in consecutive samples of the process fluid, the samples being acidified and filtered prior to the chromatographic separation
Patent ES-2277930-T3 (ES)
Inventor: CALDIROLA PATRIZIA
IPC: A61K31/55
Filed: 2001-07-19
Granted: 2007-08-01
Abstract: The invention provides a method of treatment or prophylaxis of obesity, comprising administering to a patient in need of such treatment a therapeutically effective amount of an aryl sulfonamide compound of formula (I) or formula (II) wherein the substituents are as described in the specification in which E is -SO2NH- or -NHSO2.
Patent ES-2311537-T3 (ES)
Inventor: OTOMO EIICHI
IPC: A61K31/4015
Filed: 2001-08-22
Granted: 2009-02-16
Abstract: N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide and salts thereof are used for the preparation of medicaments, particularly of pharmaceutical compositions containing it as an active ingredient, for the treatment of neurodegeneration, in particular in post-stroke human patients. The early administration of nefiracetam or its salt in said pharmaceutical compositions after a stroke allows an improvement of the Acivities of Daily Living and the recovery, or at least in improvement in the recovery of, post-stroke patients.
Patent ES-2236325-T3 (ES)
Inventor: DENZER HORST
IPC: A61K8/39
Filed: 2001-10-26
Granted: 2005-07-16
Abstract: The invention relates to optically transparent composition containing hydrophobic silicone oil and a comparably low amount of wash -active matter, being suitable as a hair treatment composition such as a shampoo. In particular, it provides an optically transparent aqueous composition comprising (a) a hydrophobic silicone oil in an amount of 1-3 wt.-% with respect to the total weight of the composition; (b) ethoxylated glycerides derived from carboxylic acids having 6 to 22 carbon atoms; and (c) an anionic surfactant; wherein the weight ratio of component (b) to component (a) is in the range of 1:1 to 10:1; and wherein the total amount of the components (b) and (c) is in the range of 10-25 wt.-% with respect to the total weight of the composition. The invention also provides a method for preparing the above composition.
Patent ES-2280409-T3 (ES)
Inventor: THIRIOT LAURENT
IPC: D03D11/00
Filed: 2001-10-26
Granted: 2007-09-16
Abstract: The invention concerns a textile surface having at least a high-visibility face. It is obtained from yarns or fibres of at least three types, of blanketing yarns or fibres, heat-stable yarns or fibres and high-visibility yarns or fibres. The surfaces provide excellent protection against fire and flames.
Patent ES-2237609-T3 (ES)
Inventor: SAGLITZ MARIO
IPC: B61K9/12
Filed: 2001-12-11
Granted: 2005-08-01
Abstract: In a process and assembly to monitor the condition of railway wagon (10) wheel bearings, an transducer records the characteristics of individual wheel bearings in a set of wheel bearings. The transducer continues in unmonitored use recording the characteristic values at fixed intervals of between 10 and 30 seconds for continual evaluation.
Patent ES-2371335-T3 (ES)
Title: Identificación y modificación de epítopos inmunodominantes en polipéptidos.
Inventor: KOREN EUGEN
IPC: C07K16/24
Filed: 2001-06-04
Granted: 2011-12-30
Abstract: Método de modificación de un polipéptido terapéutico, que comprende: (a) identificar por lo menos un epítopo inmunodominante en el polipéptido utilizando un anticuerpo o población de anticuerpos obtenidos de un humano sin tratar o animal sin tratar o una población de los mismos, donde el polipéptido tiene una secuencia de aminoácidos idéntica a la secuencia nativa de un homólogo de polipéptido endógeno en el mismo humano o la misma especie de animal o un fragmento biológicamente activo del polipéptido endógeno, donde el anticuerpo o anticuerpos no inhiben sustancialmente una actividad terapéutica del polipéptido; y el epítopo inmunodominante no se localiza en una región del polipéptido que proporciona una actividad terapéutica del polipéptido; y (b) modificar el epítopo inmunodominante para reducir una respuesta inmune al polipéptido a la vez que mantiene una actividad terapéutica sustancial del polipéptido.
Patent ES-2558562-T3 (ES)
Title: Procedimiento y aparato para mejorar el rango dinámico de ultrasonido detectado por láser en materiales atenuantes
Inventor: DRAKE THOMAS
IPC: G01N29/24
Filed: 2001-12-19
Granted: 2016-02-05
Abstract: Sistema (200) para detectar desplazamientos ultrasónicos (102) en un material sometido a prueba (104), que comprende: una fuente de luz láser simiente que proporciona un primer haz de láser (140) que presenta una trayectoria de propagación; un conjunto de modulador (132) situado en dicha trayectoria de dicho primer haz de láser (140) que puede hacerse funcionar para proporcionar un impulso de salida (P(t)); un sistema de inducción de ultrasonido que induce desplazamientos ultrasónicos (102) en el material sometido a prueba (104); un sistema de detección que aplica dicho impulso de salida de dicho primer haz de láser (140) al material sometido a prueba (104) con el fin de detectar los desplazamientos ultrasónicos (102) y generar por lo menos una señal de salida (142); y un procesador de datos para procesar dicha por lo menos una señal de salida (142) de dicho sistema de detección para obtener datos representativos de dichos desplazamientos ultrasónicos (102); caracterizado por que: el impulso de salida (P(t)) del primer haz de láser (140) presenta un perfil de impulsos dependiente del tiempo que presenta una forma de impulso gaussiana, una forma de impulso lorentziana, una forma de impulso de pendiente lineal/con fijación de ganancia, o una forma de impulso exponencial.
Patent ES-2227338-T3 (ES)
Title: Taco expansible.
Inventor: FILIPP HORST
IPC: F16B13/08
Filed: 2002-03-06
Granted: 2005-04-01
Abstract: Taco expansible, con un manguito (2) que está dotado por sectores de una rosca interior (10), en la que puede enroscarse un tornillo (3), y que presenta en un extremo primeras ranuras longitudinales (4) mediante las cuales se forma una región expansible, en la que engrana con expansión una pieza expansible (7) unida al tornillo (3), que presenta un cono (8), al enroscar el tornillo (3), caracterizado porque por el lado del manguito (2) situado enfrente de las primeras ranuras longitudinales (4) están previstas segundas ranuras longitudinales (5), que se extienden hasta el lado frontal libre asociado, y porque en la región de las segundas ranuras longitudinales (5) está prevista hacia el lado frontal libre una región (11) con rosca interior, cuyo diámetro de rosca es menor, con la misma inclinación, que el diámetro de la rosca del tornillo (3), o sin rosca, en donde después el diámetro interior es menor que el diámetro exterior del tornillo (3).
Patent ES-2227346-T3 (ES)
Title: Union a tope de placas de trabajo.
Inventor: SCHOCKINGHOFF JOSEF
IPC: A47B77/00
Filed: 2002-04-11
Granted: 2005-04-01
Abstract: Unión a tope de placas de trabajo (1; 2), precisamente placas de trabajo de cocinas, que son apretadas juntas con sus superficies frontales opuestas (1f; 2h) adyacentes una a otra y cuyas superficies de trabajo (1a; 2a) en el estado de apretadas juntas están situadas enrasadas, estando previstas en las superficies frontales (1f; 2h) ranuras longitudinales que forman un canal longitudinal común en el que están situados elementos de alineación (4) pasantes en la junta de separación (3), los cuales encajan respectivamente en ambas ranuras longitudinales y que con sus superficies superiores (4a; 4b) y superficies inferiores (4c; 4d) ajustan con acoplamiento de forma en los flancos laterales (1c; 1d; 2c; 2d) de ambas ranuras longitudinales
Patent ES-2361732-T3 (ES)
Inventor: ROLLI KILIAN
IPC: A61F13/20
Filed: 2002-10-04
Granted: 2011-06-21
Abstract: The force for moving each swage (2) is transmitted on to the swage via a pressure transmission element (9), which is connected flexibly to the swage. The direction of the power line is aligned with the movement of the swage at a point during the pressing process. The resulting preliminary product consists of a tampon core and oblong ribs extending radially outwards. <??>An Independent claim is made for the associated installation.
Patent ES-2282369-T3 (ES)
Title: Sistema centralizado para el control remoto de plantas de irrigacion.
Inventor: BATTISTUTTO ROBERTO
IPC: G05B15/02
Filed: 2002-12-12
Granted: 2007-10-16
Abstract: Un sistema de control centralizado que comprende una computadora personal (1), al menos una interfaz de comunicación (2) que tiene una primera memoria (14) adecuada para memorizar una pluralidad de comandos (C1, ..., C6) y una segunda memoria adecuada para memorizar los eventos (15); al menos una unidad de control electrónica (4) que tiene un microprocesador (C) y una tercera memoria (NVM) adecuada para memorizar el programa de control necesario para el funcionamiento de dicho microprocesador; siendo dicha unidad de control (4) adecuada para controlar una pluralidad de válvulas solenoides (8, ..., 8'') y una válvula principal (7); estando conectada dicha computadora principal (1) a dicha, al menos una, unidad de control electrónica (4) por medio de dicha, al menos una, interfaz de control (2) a través de un medio de comunicación (90, 100, 11, 120); estando provista dicha computadora personal con un programa de gestión residente en dicha computadora personal (1); caracterizada porque dicho programa de gestión proporciona una pluralidad de comandos (C1, ..., C6) que se pueden transmitir a dicha, al menos una, interfaz de conexión (2), dichos comandos (C1, ..., C6) que se pueden transmitir comprenden un primer comando (C1) que contiene instrucciones para cargar los contenidos de dicha memoria tercera (NVM) en dicha memoria primera (14), un segundo comando (C2) que contiene instrucciones para leer los contenidos de dicha memoria primera (14) y transmitirlos a dicha computadora personal (1), un tercer comando (C3) que contiene instrucciones para escribir directamente en dicha memoria primera (14), un cuarto comando (C4) que contiene instrucciones para leer directamente los datos contenidos en dicha memoria primera (14), un quinto comando (C5) que contiene instrucciones para leer los datos contenidos en dicha memoria segunda (15); un sexto comando (C6) que contiene instrucciones para seleccionar entre un primero y un segundo modos de operación.
Patent ES-2252421-T3 (ES)
Inventor: JARVELA JORMA
IPC: E21B7/20
Filed: 2002-02-18
Granted: 2006-05-16
Abstract: The invention relates to a method for drilling, being carried out by a drilling apparatus, having a drilling device ( 1 ) that comprises a casing part ( 2 ) and a drilling unit ( 3 ), in the drilling head (I) of which there are first drilling means ( 4 ) for drilling a center hole and second drilling means ( 5 ) for reaming of the center hole for the casing part ( 2 ) as well as flushing flow arrangement ( 6 ) for flushing of waste, being generated. At least during the drilling situation, the first drilling means ( 4 ) are coupled by a power transmitting and, in order to enable removal of the same from the hole, removable arrangement, such as a bayonet coupling or like, with the second drilling means ( 5 ). A feed flow ( 6 a) of flushing medium, being carried out centrally, is being transferred by internal drillings (X 1 ) inside a first frame part ( 4 a), belonging to the first drilling means ( 4 ), to its outer periphery and a return flow ( 6 b) of flushing medium, in order to accomplish a so called reverse circulation of flushing medium, from the drilling surface (pp 2 ) of the first frame part ( 4 a) through internal drillings (X 2 ) therein into a space (z) between the first frame part ( 4 a) and the casing part ( 2 ). The invention relates also to a drilling apparatus for exploitation of the method described above.
Patent ES-2264728-T3 (ES)
Inventor: OLEK ALEXANDER
IPC: G06F19/00
Filed: 2002-03-01
Granted: 2007-01-16
Abstract: This invention is related to methods, systems and computer program products for determining the biological effect and/or activity of drugs, chemical substances and/or pharmaceutical compositions using their effect on DNA methylation as a marker for their biological effect(s). The invention is further related to the use of the inventive methods, systems and computer program products in obtaining new biologically active compounds for new and effective medicaments and treatment strategies of, in particular, human diseases.
Patent ES-2356729-T3 (ES)
Title: Uso de antogonistas específicos del receptor de glucocorticoides para el tratamiento del delirio.
Inventor: BELANOFF JOSEPH
IPC: A61K31/56
Filed: 2002-05-06
Granted: 2011-04-12
Abstract: Un antagonista del receptor de glucocorticoides específico para su uso en un método de mejora de los síntomas de delirio en un paciente que lo necesite, a condición de que el paciente no necesite de otro modo tratamiento con un antagonista de receptor de glucocorticoides y tenga un nivel de cortisol en sangre que sea menor de 25 g/dl por la mañana y 15 g/dl o menos por la tarde, uniéndose el antagonista de receptor de glucocorticoides específico al receptor de glucocorticoides Tipo II con una afinidad que es al menos 100 veces mayor que la afinidad para el receptor de glucocorticoides de Tipo I.
Patent ES-2232759-T3 (ES)
Inventor: BELLER KLAUS-DIETER
IPC: A61M15/00
Filed: 2002-04-24
Granted: 2005-06-01
Abstract: A device for spraying a liquid, wherein the liquid is contained in a container that, in an initial state, is a unitary closed container comprising a head to be broken off or sawed off for providing the removal opening, has a spraying device to be arranged on the removal opening of the container. The spraying device has a basic spraying unit and a connecting adapter for the container, wherein the connecting adapter is fixedly connected to the spraying unit. The connecting adapter has an annular seal that rests sealingly on the container. The connecting adapter is essentially cylindrical and has a lower peripheral end provided with the annular seal. A sleeve having an upper open end and a lower end is provided. The lower end of the sleeve has a bottom. The sleeve receives the container. The sleeve is connected with the upper open end to the connecting adapter.
Patent ES-2300456-T3 (ES)
Inventor: MOSBEY DERAL T
IPC: A61K47/34
Filed: 2002-08-08
Granted: 2008-06-16
Abstract: A composition comprising a water-in-oil emulsion comprising a polyetherpolyester emulsifying polymer; a water phase; an oil phase; and one or more antimicrobial agents, and methods of using such compositions are described herein.
Patent ES-2367255-T3 (ES)
Title: Uso de tat del hiv-1 biológicamente activa, fragmentos o derivados de la misma, para direccionar y/o activar células de presentación de antígeno, y/o para suminsitrar moléculas cargo para la vacunación preventiva o terapéutica y/o para tratar otras enfermedades.
Inventor: ENSOLI BARBARA
IPC: A61P31/04
Filed: 2002-07-26
Granted: 2011-10-31
Abstract: Una composición farmacéutica que comprende una Tat del HIV biológicamente activa aislada, nativa, sustancialmente monómera, o un fragmento aislado o un derivado aislado de la misma, en la que la Tat del HIV, fragmento, o derivado: (i) contiene el dominio RGD de una Tat del HIV-1; (ii) tiene actividad coadyuvante; y (iii) está mezclada con una molécula antigénica elegida entre el grupo que consiste en: (a) un antígeno de una célula tumoral; y (b) un antígeno de un patógeno, en el que dicho patógeno es virus del herpes, virus de la hepatitis, virus de la gripe, virus de la varicela, virus de Epstein-Barr, virus del herpes 8 humano, citomegalovirus, virus del papiloma, Mycobacterium tuberculosis, Listeria, Streptococcus, Staphylococcus, Pneumococcus, Clostridium tetani, Mycobacterium, Meningococcus, Helicobacter, Salmonella, Vibrio cholerae, Candida, o Plasmodium.
Patent ES-2276961-T3 (ES)
Inventor: LEIMU JUHA
IPC: D21F7/00
Filed: 2002-11-07
Granted: 2007-07-01
Abstract: A blow box (18) for supporting the web run in a paper machine or the like, which blow box comprises members for maintaining a negative pressure at least in one negative pressure region (24) between the wire (20) and the blow box. The members comprise a blocking member (30, 32), which is arranged, regarding the wire's running direction, at the beginning and/or at the end of said negative pressure region, which extends across the wire and projects towards the wire, and which is movable in relation to the blow box, and blowing members (34, 36), with which air is ejected with blows between said blocking member and the wire from said negative pressure region and/or with which air is prevented from entering this negative pressure region. The blocking member is connected to the blow box by a hinge member (40, 42), which allows the blocking member to rotate around the articulation point of the hinge member due to the pressure difference between the pressure acting on the blocking member's blocking surface (30', 32') directed towards the wire and the pressure acting on the blocking member's back surface (50, 50') directed away from the wire.
Patent ES-2325489-T3 (ES)
Inventor: RHELIMI ALAIN
IPC: G06K19/07
Filed: 2002-11-29
Granted: 2009-09-07
Abstract: The data transmission between smart card (4) and user is through a computer (1), and is performed under the universal serial bus (USB) protocol, through first and second contact pads on the smart card chip. A third contact pad is used to communicate data with a specific visual or audio communication device (6). The visual or audio link is used to communicate private data such as a user's PIN.
Patent ES-2284986-T3 (ES)
Inventor: HERKT RONALD DR
IPC: E03D13/00
Filed: 2003-01-17
Granted: 2007-11-16
Abstract: The urinal (1) has a membrane valve (5) at the outflow opening (13). In one position, the valve covers the outflow opening with a gas- and fluid-tight sealing action and, in a second setting, the valve is opened to allow urine to flow away. A flushing system is operated manually or by remote control, to deliver flushing water at time intervals through a distributor (9) at the urinal basin (12).